CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_013172	Brachybacterium faecium DSM 4810, complete sequence	7 crisprs	csa3,DEDDh,DinG,cas3,WYL,Cas9_archaeal	0	3	0	0

1. NC_013172

CRISPR-Cas detection and classification

Crispr_ID: NC_013172_1

• CRISPR_ID: NC_013172_1
• CRISPR_location: 253416-253513
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_013172_1

Consensus_repeat	Method
CGGCACCGAGGACGACCTGCTCG	CRISPRCasFinder

spacers of NC_013172_1

>1.1|253439|52|NC_013172|CRISPRCasFinder
GCCTGCTCGCCCAGGCCGATCCGGCCGCGCTGCCCTCGCTGTTCCTGGACTG

CRISPR arrays and Neighbor proteins around NC_013172_1

CRISPR arrays

The CRISPR arrays of NC_013172_1

>merge|NC_013172|1|253416-253513|CRISPRCasFinder
CGGCACCGAGGACGACCTGCTCGGCCTGCTCGCCCAGGCCGATCCGGCCGCGCTGCCCTCGCTGTTCCTGGACTGCGGCACCGAGGACGAGCTGCTCG

>NC_013172|1|1|253416-253513|CRISPRCasFinder
CGGCACCGAGGACGACCTGCTCG	GCCTGCTCGCCCAGGCCGATCCGGCCGCGCTGCCCTCGCTGTTCCTGGACTG
CGGCACCGAGGACGAGCTGCTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_013172.1|WP_012803868.1|246272_246929_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_013172.1|WP_012803877.1|255822_257199_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274819
NC_013172.1|WP_012803882.1|261476_264080_+|FAD/NAD(P)-binding-protein	unknown	unknown	gnl|CDD|379196
NC_013172.1|WP_012803865.1|242652_243807_+|winged-helix-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|377630
NC_013172.1|WP_012803874.1|253765_254050_+|hypothetical-protein	unknown	unknown	gnl|CDD|225225
NC_013172.1|WP_012803871.1|250929_251283_-|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_012803872.1|251312_252746_-|DUF3459-domain-containing-protein	unknown	unknown	gnl|CDD|200491
NC_013172.1|WP_164930104.1|260219_261236_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|223836
NC_013172.1|WP_012803876.1|254550_255465_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NC_013172.1|WP_012803867.1|245497_246127_-|pyroglutamyl-peptidase-I	unknown	unknown	gnl|CDD|237299
NC_013172.1|WP_012803878.1|257195_258284_-|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274819
NC_013172.1|WP_164929826.1|254065_254485_-|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_012803883.1|264220_265978_-|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl|CDD|223732
NC_013172.1|WP_164930105.1|259323_260151_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224051
NC_013172.1|WP_164929825.1|240565_241102_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NC_013172.1|WP_174265952.1|247067_248879_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NC_013172.1|WP_012803879.1|258280_259327_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270225
NC_013172.1|WP_012803870.1|248890_250717_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_013172.1|WP_012803866.1|243865_244783_+|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl|CDD|366759
NC_013172.1|WP_012803864.1|241273_242533_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_013172.1|WP_012803868.1|246272_246929_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.02681e-13
NC_013172.1|WP_012803877.1|255822_257199_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	2.10568e-128
NC_013172.1|WP_012803882.1|261476_264080_+|FAD/NAD(P)-binding-protein	gnl|CDD|379196	pfam13454, NAD_binding_9, FAD-NAD(P)-binding.	1.74732e-31
NC_013172.1|WP_012803865.1|242652_243807_+|winged-helix-DNA-binding-domain-containing-protein	gnl|CDD|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	6.48526e-26
NC_013172.1|WP_012803874.1|253765_254050_+|hypothetical-protein	gnl|CDD|225225	COG2350, COG2350, Uncharacterized protein conserved in bacteria [Function unknown].	2.57982e-17
NC_013172.1|WP_012803872.1|251312_252746_-|DUF3459-domain-containing-protein	gnl|CDD|200491	cd11354, AmyAc_bac_CMD_like, Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins. Cyclomaltodextrinase (CDase; EC3.2.1.54), neopullulanase (NPase; EC 3.2.1.135), and maltogenic amylase (MA; EC 3.2.1.133) catalyze the hydrolysis of alpha-(1,4) glycosidic linkages on a number of substrates including cyclomaltodextrins (CDs), pullulan, and starch. These enzymes hydrolyze CDs and starch to maltose and pullulan to panose by cleavage of alpha-1,4 glycosidic bonds whereas alpha-amylases essentially lack activity on CDs and pullulan. They also catalyze transglycosylation of oligosaccharides to the C3-, C4- or C6-hydroxyl groups of various acceptor sugar molecules. Since these proteins are nearly indistinguishable from each other, they are referred to as cyclomaltodextrinases (CMDs). This group of CMDs is bacterial. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_013172.1|WP_012803876.1|254550_255465_-|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.75395e-61
NC_013172.1|WP_012803867.1|245497_246127_-|pyroglutamyl-peptidase-I	gnl|CDD|237299	PRK13197, PRK13197, pyrrolidone-carboxylate peptidase; Provisional.	6.27662e-79
NC_013172.1|WP_012803878.1|257195_258284_-|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	1.05646e-25
NC_013172.1|WP_164930104.1|260219_261236_-|ABC-transporter-permease-subunit	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.41423e-65
NC_013172.1|WP_012803870.1|248890_250717_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.32816e-127
NC_013172.1|WP_164930105.1|259323_260151_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.30083e-144
NC_013172.1|WP_164929825.1|240565_241102_+|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	4.46187e-63
NC_013172.1|WP_012803883.1|264220_265978_-|SulP-family-inorganic-anion-transporter	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	7.29919e-118
NC_013172.1|WP_012803879.1|258280_259327_-|ABC-transporter-substrate-binding-protein	gnl|CDD|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.10244e-57
NC_013172.1|WP_174265952.1|247067_248879_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.20711e-168
NC_013172.1|WP_012803866.1|243865_244783_+|rhomboid-family-intramembrane-serine-protease	gnl|CDD|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	1.2082e-30

Protein sequences

>NC_013172.1|WP_012803872.1|251312_252746_-|DUF3459-domain-containing-protein
MTTVPAPSWIRDAICWQVYPLGFCGAPRHREDLGGEGYGGADGENVVHRLQRLHGWLDHLVGLGANVLLLNPIFNSVSHGYDTLEHRRLDPRLGDEEDFDALIAACHERGIRVVLDGVFNHISHLHPVARQALSAGPGTEDGARIRWAGTSPYGFEGNADLVEIDLADAVIQDRVVEIMSRWLERGADGWRLDAMYAAGAETWAPILERVRAAHPEAWILGEVIHGDYPAFAAASTAHSITQYELWKAIWSSLADHNLFELAHALGRHQEFLEAEGGAHPLTFVGNHDTTRIASQLPDGRDLAAAIALLALLPGIPAVYAGDEFGATGVKEERAGGDDAIRPWFPGSPDEVVAAAGSAQSAPGGPDHLTLLKAEAAERILEVHRRLFSLRRREPWLAAATVEVDEGSLENTWVQITLTPRAEDAAAEGPLTLVLNLGDEERPAPGEVLETVSGADMLDGVGPAAPGAVPAHGAAVVR
>NC_013172.1|WP_012803871.1|250929_251283_-|hypothetical-protein
MSMSIKPAESVHTAPVVALGLVGGWLTARETGIRPLGGVVLAAAGLYAGRTWLARRGPATTAALGATYVLGFGLSHPLAKKIGPWPAVLGVTAAAAGAAALLSDAAYGDWAPADADA
>NC_013172.1|WP_012803870.1|248890_250717_-|ABC-transporter-ATP-binding-protein
MLGTMRRLWTTVRPIRFRLYLGLLSAMTASIVALMIPQVLEFIVNRLGTDATAATIWTGGAIVLGLGVVEASLIWLRRTFAVAPSTTVEKQIRVSFYAKVQHMPVTFHDGWGSGQLLSRMMSDINQIRRWIAFGMIMAVTNVVTITVGMTLLVRSSAILALIFFAAAVPVTIIAYLFNRSYSVLSRLSQDQNGDLATTIEQSVQGIRVLKAFGRGPSALEGFTEQAEELRRTEVRKATAIARFDMFMFMLPELALGVALLVGLHLTAAGTISTGQLASYFATATLVVGPVRMLGMLLGQAVNATTALDRHYEVMDSENTITSDDATVHPELASSTGAVSLRGVHFRYADAPAHVPDVIDGADLDIRPGETMALVGVTGSGKSTLLQLVPRLYDVTEGAITIDGVDIRDMDLMALRTLTAVAFEDATLFSDSVRENVLLGADRSLSDEEAEELLHLALRTADATFALELPEGVDTRIGEEGMSLSGGQRQRLALARAIAARPAVLLLDDPLSALDTKTEETVTERLREVLHGTTTLIVAHRTSTVALADRVALLDNGRVVDVGTHTELMASSARYRWVIANQEEERRRDQDIETLTGELELRAIQEEGR
>NC_013172.1|WP_174265952.1|247067_248879_-|ATP-binding-cassette-domain-containing-protein
MKNQRDDQNDPEHQTYSEEENRASRKRSFALLGELIAPVKKQFLLMAIMVVIAQLAVVAGPAIIAWGIDHGLPSLLAGDSGPAFQAAALAVGAAIVGGVLTYGYVRQSVVVGQRMLLALRRKVFRFTQKQDLEFHESYTSGRIVSRQTSDMEALRELLDSGVNVMVGASLSMVFTIVLIVTMDWVTGVVMLLMLIPCLALTVWFQKRSRIEYRAIRTHSARLIVHFVEAMAGIRAVKAFRKEGRNQAEFDGLAQDYRDASMRSINVFGIYQPALRVLANVTIAAVLVVGGFRVLHGDLQVGVLVALVLYSRRFFQPVDEIANFYNAFQSAVAALEKIANLLAVQPHVKESPSPTALPSSNGQVDFEDVSFRYTEDGPIVLQPLDLHIPAGQTIALVGQTGAGKSTVAKLIARFYDATQGSVKLDGVDLRDISMEDLTRNIVMVTQEAYLFSGTVADNIALGKPGASREEIERAARAIGADEFIEKLPYGYDTDVNKRGGRVSAGQRQLISFARAFLADPRVLILDEATSSLDIPSERMVQEGLTKLLGHRTSLIIAHRLTTVMIADRVLVVHGGEVVEDGSPTELVAAGGRFAALYQAWQESM
>NC_013172.1|WP_012803868.1|246272_246929_+|GNAT-family-N-acetyltransferase
MTAFPGLATIHPPSGLVLRAGDLVLRPLADADLPEYAALLRRPIFEDEHSPQVFPWYRAEPEVRVREALRFQWRLRSELSADRWTLPLGIWAGGRLIGCQDISAERFAERRTVTSGSWLTLEAHGRGYGTLMRQAMLVFAFDHLGARRAESSAVLGNAASFGVSRACGYIENGTQISSLRGSVEEEQRFLVTPETFRRPTAPVEVEGLTPALREMLGA
>NC_013172.1|WP_012803867.1|245497_246127_-|pyroglutamyl-peptidase-I
MRIDVLLSGFAPFDGAAVNESWEAARGAAPLLREVGLAVETLELPVEFGEGGRLLAAAVRQHVPRLVIATGLAAGRTAITPERVAINVRDARIPDNAGASPVDAPVVPDGPAGRFSTLPIKAMTAALAADGIPAAVSQTAGTYVCNDVFYLLQHLLATDASLTGTRGGFVHVPAADAVDSETAARALARMTDVALRTEADAAVAGGAEH
>NC_013172.1|WP_012803866.1|243865_244783_+|rhomboid-family-intramembrane-serine-protease
MERPSYGYSAEDAPDPQGTPVCPRHPDRVSYVRCKRCERPACPDCQRPTSVGVLCVDCEREISRQQASTRPRNAMGAGMGRRTPYVTYTLIGLSVLAFVGQTLAPQIVQQLGIFAPYRAVFMPWTFFTAGFLHGGILHLALNMYALWIVGQYLEQTLGHVRYAAVFLTAVLGGHTAVYLLADPLSSAWITGTLGASGGVFGLFAAMFIVNRHLGGQTAQIVVLIVLNLVLTFTIPGISWQGHLGGLVIGAAVTAGMFALRPKAGPGADRQALARRSALVHSGVVAAAAVLCVALIVAKTLMVLSL
>NC_013172.1|WP_012803865.1|242652_243807_+|winged-helix-DNA-binding-domain-containing-protein
MTARHLAGARILAQGLVGPPRFTDPAQAARAFGAHQGQDLPGVIASLALRTGGDLAGVLAAFDRGEVVRGYPMRGTVFAVAADSLAWLTQLCAGGPLRSAISRRPALDLEERHIDRAREVLVERAGPHSAPGEGRGVLRRELLEAWEAAGVPVDRGRGYHVLVELIAMGDAAYGPWREGETAVVHARRWLPAGSDLEGTFNGDRVAATAELALRYLTSHGPAGERDLAWWSKLPLGALRAALPQSADRLESGFADRDGRLHAREDEARGGSGERLWWRPGLAEEYAQQERETMRELLLPGFDELVLGYRDRLFLMDEERHRALAPGNNGVFKRAALRRGELVGVWSRTGAAGRRKLVLQEARPVSDAQRRRFEKLFAAFPYTIV
>NC_013172.1|WP_012803864.1|241273_242533_-|hypothetical-protein
MTSRRQFRSTPALLARRGVLLSGPALLLAGCGLLPGGDDAAPTDGTTAEDADDAAAEGSVEDAADDVDDAQAVEDADEQAPGAASTQAVLDITVVEVEDEIVAGGLMQRLEGSETLRHPFAEVTVTSTALLDSLTAEQYTALTGEEVPPADGTGEDGDEPVPATTLLPGTMKKFLLAAWESTDAQWVPEPRSGPSTTLHIAYGGNDDIRVTSVQSGDTERSGIVLAVVDATPDPRAVTLRASIEDGAQDISLVDGSIVSTVAPRLYTGDYAVEVSDAGVFETEIEDEYGTAPMQVRGTVESALLTSFLYPDSTATWGGMLKWADEDEVFVVVQLDWEKNYSSNITELGEVVLELPDGTELTPEQDPVRIFSHHGSHTATFTVPAHLETATVRITPRYQKALDSDFDETHDPLTATLTFT
>NC_013172.1|WP_164929825.1|240565_241102_+|peptidylprolyl-isomerase
MFATLHTNHGDIRLELFPNHAPKTVENFVGLAEGTKEFSDPETGEKVTRPFYDGVIFHRIIAGFMLQGGDPLGTGTGGPGYTFDDEISEKNFNEPYVLAMANAGQRRNALTGRPSGTNGSQFFITVGPTPHLQGKHTVFGQVADEDSKKVVDAIEQVKTDMRDRPLEDVVITSVTIEK
>NC_013172.1|WP_012803874.1|253765_254050_+|hypothetical-protein
MATFAVQYTYTDDAERVAIHRPEHREHLAELHREGTLLLSGPLGGGPGALLVVAADSAEDALAKLDGDPFKRERVIVDRVAREWTVVIGAIPGA
>NC_013172.1|WP_164929826.1|254065_254485_-|hypothetical-protein
MLLTALLVLAGQWIAAVAVAVFSLFMAYWTSPLREGDHVPLATALAQRTPGSAVVLWAPGNPLSSRLQVAIRSPREDVAWVNVHRDVQAQQLLAEHGGAEALPLVLVGESVQARATAAELLDLQDLERRRADGEEPPAP
>NC_013172.1|WP_012803876.1|254550_255465_-|LysR-family-transcriptional-regulator
MDPRRLLIFRTVVRNGSIGAGARELGWTQPAVSQHLAALEKEVGTQLLLRSSSGITPTEAGSRLAAHAEAIAAQLHAAEEELADITALRRGTVKFGTFPSAAAMLLPPVLNRLSETAPDLDVTFSELEPPDAVVALREGELDLALVFRYPCSDIGDEGTLEWTPLMEDRVMVVLPRDHPRAEDPDLVLGDLAEDPWIAGCERCRANLISSARRAGFSPRVRHSTDDTTVVLQLIMHGGGVALMPETALDAAPAADLVVRAIPDLDNRMIGLLNRRGALAIPAVGALRDALVAETTERLATAVMI
>NC_013172.1|WP_012803877.1|255822_257199_-|LLM-class-flavin-dependent-oxidoreductase
MTTAPSILRNDAPLSPEAAALATGPAEHPLHPAHTPTGQLAFGVFFQGVNSSTIWRLPSSGDQVAWESFASLARAAERGRFAAFFLGEGLRLREHRGVPFELDVAGRPDAQTLLAALAGVTENIGLVATQNTTYNDPVDLARRLQTLDLLSGGRAGWNIVTTDNAWTGENFRRGGYLDHADRYTHAGAFVRVAEQYWRGERIAHEGAHYSVRAQGDLPRSAQGRPVLFQAGASPAGQDFAARSADVVFSPHGTLETAAEFRRSIVERTVAAGRDPGSVKILPGAEIILAPTEAEAEEKVHWVRDLQIGPEQAIALLEQYWGRDLSDFDPDGPLPDVPPEVVESGVTRGAGFQFAKAEELTRAWREEAAEKGQSILEFARARAGARRGTFTGSYDAVAERLVEFARLGAIDGLNITPWLIPSGLDDIVDHLIPRLQERGVYPAEYAGPTLRENLGLPPL
>NC_013172.1|WP_012803878.1|257195_258284_-|LLM-class-flavin-dependent-oxidoreductase
MSTTVVNPVPAARPRGADPAGPLPVLAVDLVTDPSLPGGLAELARGLEEAGAGALTLSDGGLHPIHVAAHLAPLTSTIGLLPRTDAIYVEPFHLATQLMSLDHISHGRAGWLLQAETDPAVAAAVGRTVLGLEATAREAADVLVAARRVWDSWAPDAVVRDTERGVYVDAARLQYTDIETETFSVRGPAITPRSPQGLLPALVADTDRAAVGERVRGELADGRVLDLDVSGGARAKQLAARIEAARADGVGRAAADGATTDAADGADGADRADGAAAVGADGAATGTAGTVRLVRLVGLDLEADPLGTVAQLAADLRARGLIAPLPRQHASLRSQLGLPPVPFRLDPARRSDRARLAPEESA
>NC_013172.1|WP_012803879.1|258280_259327_-|ABC-transporter-substrate-binding-protein
MTALPPPSRPASAAAPATRRPTGPRLTRRALAASGLLLPAALLAACSDPAPAASGSGGSGASDGGGESDSGIDTSGTQELIRATADEEIAALLPPEIADSGVLRVGINGTSSAPLSFLADDNQTYIGSEIDIARIVADKLGLEFELKLTTWENWPLKLEAGEFDAVHANIGVNAERLEKFDFASYRAAYMSFLVKEGAEFWLEDPDSLSGRLIAVGNATNQERILLDWNAELEAEGKEPAQLKNYSTDADTLLALGSGRIDGYLSPFASLSFIAARRDDFELQGRINAGWPDETLVAGTFARGSGLAEPYAAALNALIADGTYAQVLERWQLSEEALTESRVHTEETP
>NC_013172.1|WP_164930105.1|259323_260151_-|ATP-binding-cassette-domain-containing-protein
MVEIRGVHKSFGDLEVLRGIDLRIEPGSVTVILGPSGSGKSTLLRSINHLEPVTQGLISVDGEVIGYRRDGDLLHELHEREVLRQRTAIGMVFQSFNLFAHMTALANVVEAPRRALGIPRRRAEARARELLALVGLSDKTEAYPRQLSGGQQQRVAIARALALDPKVLLFDEPTSALDPELVEEVLEVIRSLARAGTTLVIVTHEIPFARDVADTVVFMDRGRIVEQGPPAEVLDRPRHDRTRAFLQRVRTDAGPPSDLSTTTPDLPLHHPEDPS
>NC_013172.1|WP_164930104.1|260219_261236_-|ABC-transporter-permease-subunit
MSCPRPDASADGPTADASAADGSAPAAHAPEPPAEDLSHLRVVPAKHPGRLVLALLVGLAVLVVLYSFVTNPRWEWGVVAQWFFAESIIRGLLETLRLTAAAGAIGFGLGLVLALMRLSKSSLISGVSWTFSWVFRSTPLLVQLLLWYNLGYLYEQVSLGIPFTGATFFEARTSDLMTPMLAAILGLGLHQAAYAAELIRGGILSVDQGQLEAASALGIPARDRSLRIVLPQAMRAILPPAFNEIIGLVKGTSIVYVLAHAELFFTVQLIYGRTQQVLPMLLVATLWYVVITSALSVGQYYIERHFSKGALRTLPPTPLQSLRARLGRRRPTPTGAPA
>NC_013172.1|WP_012803882.1|261476_264080_+|FAD/NAD(P)-binding-protein
MTSRISPARTRLVLVGGGPRAIGVLERLGASAAQPAAAERLARTPLHVDIVDPHMPGAGRIWRAHESPLLLMNSRAADVSIHPDETVDCEGPVRTGPSLAEWAEGIRRGTIAAPTAGTERLAEIEALQPTDFASRRVQALYLEWFFGQVLAALPSTVSVAVHRTTATAVRSADGVRPAAAVGPADGTAWTVELEDRAPLHADLLLLAAGHTDSRPSAERHQLAVFARRHGGTYLAPSQASDAQLDLLAPGQDVIVRGMGLAFIDLMALLSEGRGGVFEPAPLPGDPDRLSYRPSGREPRLWVGSRRGVPYHSKVRDEGAPAGPGDLVHVTAENLRAREDAQGRLDFRADVVPLIAAEIRRWVPGAPSAAPGEDPLAWLDDPLSWLEGEAHPQVTRDAVVRHIETDLHARTRGDASSARALFQLLLRLHGVLVDQLPATRLRPGAQGDYPRWWHSLFSFVDSGPPPHRLHQLLALERAGVVRFLGPRVQVRAEESTGRFTARGAAGAHVTADALLDAFLPEASLVESTNPLLRDLVTGGSAAVGRESAATPGSLEVDARHSVIGPDGTARPRLWAVGPWTSELPIGAFARPHTNAPCHRRNDALGRELLEAALRHGEAAASQGERAPSQGAGALRHGETVLRHGETVRRTGQPARLGVMGPGKIGRALARTALRRGLEVRVSGRAPAAALAAALPGAHPVEVAELASTCEVVAITVPLHVALTLDPATLHGAVVIDATNPWGEADAAAVAAARRTLGDAEGLLSTSELLAAHLPGARVVKTLNHIGYHDVEDQGREGGDPHRRAIALAADDPQAADAVAALLHRIGFEPVRVGTLAAGRQLEPGAGLFAGWSTSEELSERRRELVRVA
>NC_013172.1|WP_012803883.1|264220_265978_-|SulP-family-inorganic-anion-transporter
MRAALVRSRDLWPAREDYRLLPKTWRKDLIAGVTVGIVALPLALGFGVSSGLTAEQGLITAIVAGLLAAVFGGSNVQVSGPTGAMVVVLVPIVANYGAGAIAAVTLLAGLLVMATGLLRLGKVVSIIPWPVIEGFTLGIACIIFMQQIPLITSSDPAVPGELSSNALVAAVQSLTTADATYLLWALGAVAIVAACMVIAPRIHPSIPGSLIGIAVVAVLAALLPGPLATIGAIPASLPAPSVPSIDPELLGVLLPAAATVAALAAIESLLSARVAGSMAETGAFDPDRELVGQGVASVGASLFGGMPATGAIARTSVSLRAGARTRAASIVHALVLLAVVYVASGPVGMIPLAALAGVLFMTAVRMVRLATVRSILTSTRSDAWIFTITALVTVSFDLIIAVLIGVALAAVVALRGAARTTGVALEPIRAEEPSPLDTSIVAVRFQGPLFFVSSERVFETVMEVGSVSVVILRLARLERVDATGAQVLAQIVRGLERRGITVLIKGVQDSHSVLFRQVGVLAALRHHKHLFVDFASALEHARSHVERERAAEELERASEQRPAAGLPPSTTPRSSGGSQPAHAPE

Crispr_ID: NC_013172_2

• CRISPR_ID: NC_013172_2
• CRISPR_location: 322272-322382
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_013172_2

Consensus_repeat	Method
CGCCTGCCCCTGCCCCGCCCCGTCTGCACC	CRISPRCasFinder

spacers of NC_013172_2

>2.1|322302|51|NC_013172|CRISPRCasFinder
TGCCCCGCCCCGTCTGCACCCGACCTGCCCTGACCTGACCCGCACCCACCT

CRISPR arrays and Neighbor proteins around NC_013172_2

CRISPR arrays

The CRISPR arrays of NC_013172_2

>merge|NC_013172|2|322272-322382|CRISPRCasFinder
CCTCGACGCCTGACCCGCCCCGCCTGCCCCTGCCCCGCCCCGTCTGCACCCGACCTGCCCTGACCTGACCCGCACCCACCTCGCCTGCCCCTGCCCCGCCCCGTCTGCACC

>NC_013172|2|2|322272-322382|CRISPRCasFinder
CCTCGACGCCTGACCCGCCCCGCCTGCCCC	TGCCCCGCCCCGTCTGCACCCGACCTGCCCTGACCTGACCCGCACCCACCT
CGCCTGCCCCTGCCCCGCCCCGTCTGCACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_013172.1|WP_164930108.1|307879_308332_-|adenylyltransferase/cytidyltransferase-family-protein	unknown	unknown	gnl|CDD|173922
NC_013172.1|WP_012803923.1|309515_311849_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl|CDD|235367
NC_013172.1|WP_012803928.1|316953_317808_+|hypothetical-protein	unknown	unknown	gnl|CDD|213994
NC_013172.1|WP_164929833.1|329784_330378_-|hypothetical-protein	unknown	unknown	gnl|CDD|224458
NC_013172.1|WP_012803937.1|332960_333689_+|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|376450
NC_013172.1|WP_012803931.1|322473_323691_+|glycine-C-acetyltransferase	unknown	unknown	gnl|CDD|235893
NC_013172.1|WP_012803926.1|314422_315427_+|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl|CDD|224013
NC_013172.1|WP_164929834.1|333678_334287_+|hypothetical-protein	unknown	unknown	gnl|CDD|319972
NC_013172.1|WP_012803934.1|328778_329750_+|glycosyltransferase	unknown	unknown	gnl|CDD|133016
NC_013172.1|WP_012803925.1|313502_314426_+|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl|CDD|130274
NC_013172.1|WP_012803927.1|315473_316913_+|sugar-nucleotide-binding-protein	unknown	unknown	gnl|CDD|224016
NC_013172.1|WP_012803920.1|306233_307676_+|sugar-transferase	unknown	unknown	gnl|CDD|274398
NC_013172.1|WP_174265943.1|334782_335151_+|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_164930109.1|330826_331951_-|glycosyltransferase	unknown	unknown	gnl|CDD|366154
NC_013172.1|WP_012803929.1|317990_321023_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_013172.1|WP_012803922.1|308577_309519_+|methylenetetrahydrofolate-reductase	unknown	unknown	gnl|CDD|273212
NC_013172.1|WP_012803932.1|323740_325045_-|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240541
NC_013172.1|WP_012803935.1|330497_330767_-|hypothetical-protein	unknown	unknown	gnl|CDD|341239
NC_013172.1|WP_012803933.1|325265_328631_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_013172.1|WP_164929831.1|312020_313436_+|hypothetical-protein	unknown	unknown	gnl|CDD|225232

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_013172.1|WP_164930108.1|307879_308332_-|adenylyltransferase/cytidyltransferase-family-protein	gnl|CDD|173922	cd02171, G3P_Cytidylyltransferase, glycerol-3-phosphate cytidylyltransferase. Glycerol-3-phosphate cytidylyltransferase,(CDP-glycerol pyrophosphorylase). Glycerol-3-phosphate cytidyltransferase acts in pathways of teichoic acid biosynthesis. Teichoic acids are substituted polymers, linked by phosphodiester bonds, of glycerol, ribitol, etc. An example is poly(glycerol phosphate), the major teichoic acid of the Bacillus subtilis cell wall. Most, but not all, species encoding proteins in this family are Gram-positive bacteria. A closely related protein assigned a different function experimentally is a human ethanolamine-phosphate cytidylyltransferase.	3.90837e-25
NC_013172.1|WP_012803923.1|309515_311849_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl|CDD|235367	PRK05222, PRK05222, 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional.	0
NC_013172.1|WP_012803928.1|316953_317808_+|hypothetical-protein	gnl|CDD|213994	cd12110, PHP_HisPPase_Hisj_like, Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like. Bacillus subtilis YtvP HisJ has strong histidinol phosphate phosphatase (HisPPase) activity. The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. HisPPase catalyzes the eighth step of histidine biosynthesis, in which L-histidinol phosphate undergoes dephosphorylation to produce histidinol. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. The PHP domain of HisPPase is structurally homologous to other members of the PHP family that have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel.	4.63188e-23
NC_013172.1|WP_164929833.1|329784_330378_-|hypothetical-protein	gnl|CDD|224458	COG1541, PaaK, Coenzyme F390 synthetase [Coenzyme metabolism].	5.9657e-21
NC_013172.1|WP_012803937.1|332960_333689_+|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|376450	pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. All of these members have the ability to catalyze the displacement of CMP from a CDP-alcohol by a second alcohol with formation of a phosphodiester bond and concomitant breaking of a phosphoride anhydride bond.	6.42726e-08
NC_013172.1|WP_012803931.1|322473_323691_+|glycine-C-acetyltransferase	gnl|CDD|235893	PRK06939, PRK06939, 2-amino-3-ketobutyrate coenzyme A ligase; Provisional.	0
NC_013172.1|WP_012803926.1|314422_315427_+|dTDP-glucose-4,6-dehydratase	gnl|CDD|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	0
NC_013172.1|WP_164929834.1|333678_334287_+|hypothetical-protein	gnl|CDD|319972	cd16344, LMWPAP, low molecular weight protein arginine phosphatase. Low molecular weight protein arginine phosphatases are part of the low molecular weight phosphatase (LMWP) family. They share a highly conserved active site motif (V/I)CXGNTCRS. It has been shown that the conserved threonine, which in many LMWPTPs is an isoleucine, confers specificity to phosphoarginine over phosphotyrosine.	1.70201e-21
NC_013172.1|WP_012803934.1|328778_329750_+|glycosyltransferase	gnl|CDD|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	9.18305e-14
NC_013172.1|WP_012803925.1|313502_314426_+|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl|CDD|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	1.78595e-165
NC_013172.1|WP_012803927.1|315473_316913_+|sugar-nucleotide-binding-protein	gnl|CDD|224016	COG1091, RfbD, dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane].	1.7539e-78
NC_013172.1|WP_012803920.1|306233_307676_+|sugar-transferase	gnl|CDD|274398	TIGR03025, EPS_sugtrans, exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase. Members of this family are generally found near other genes involved in the biosynthesis of a variety of exopolysaccharides. These proteins consist of two fused domains, an N-terminal hydrophobic domain of generally low conservation and a highly conserved C-terminal sugar transferase domain (pfam02397). Characterized and partially characterized members of this subfamily include Salmonella WbaP (originally RfbP), E. coli WcaJ, Methylobacillus EpsB, Xanthomonas GumD, Vibrio CpsA, Erwinia AmsG, Group B Streptococcus CpsE (originally CpsD), and Streptococcus suis Cps2E. Each of these is believed to act in transferring the sugar from, for instance, UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate as the first (priming) step in the synthesis of an oligosaccharide "block". This function is encoded in the C-terminal domain. The liposaccharide is believed to be subsequently transferred through a "flippase" function from the cytoplasmic to the periplasmic face of the inner membrane by the N-terminal domain. Certain closely related transferase enzymes, such as Sinorhizobium ExoY and Lactococcus EpsD, lack the N-terminal domain and are not found by this model.	1.27694e-138
NC_013172.1|WP_164930109.1|330826_331951_-|glycosyltransferase	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.02063e-16
NC_013172.1|WP_012803929.1|317990_321023_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	6.25037e-12
NC_013172.1|WP_012803922.1|308577_309519_+|methylenetetrahydrofolate-reductase	gnl|CDD|273212	TIGR00676, 510-methylenetetrahydrofolate_reductase., 5,10-methylenetetrahydrofolate reductase, prokaryotic form. The enzyme activities methylenetetrahydrofolate reductase (EC 1.5.1.20) and 5,10-methylenetetrahydrofolate reductase (FADH) (EC 1.7.99.5) differ in that 1.5.1.20 (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while 1.7.99.5 (assigned in many bacteria) is flexible with respect to the acceptor; both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as 1.5.1.20 and 1.7.99.5, this model describes the subset of proteins found in bacteria, and currently designated 1.7.99.5. This protein is an FAD-containing flavoprotein. [Amino acid biosynthesis, Aspartate family].	5.61028e-73
NC_013172.1|WP_012803932.1|323740_325045_-|MATE-family-efflux-transporter	gnl|CDD|240541	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	7.69208e-93
NC_013172.1|WP_012803935.1|330497_330767_-|hypothetical-protein	gnl|CDD|341239	cd05913, PaaK, Phenylacetate-CoA ligase (also known as PaaK). PaaK catalyzes the first step in the aromatic degradation pathway, by converting phenylacetic acid (PA) into phenylacetyl-CoA (PA-CoA). Phenylacetate-CoA ligase has been found in proteobacteria as well as gram positive prokaryotes. The enzyme is specifically induced after aerobic growth in a chemically defined medium containing PA or phenylalanine (Phe) as the sole carbon source. PaaKs are members of the adenylate-forming enzyme (AFE) family. However, sequence comparison reveals divergent features of PaaK with respect to the superfamily, including a novel N-terminal sequence.	0.00278481
NC_013172.1|WP_012803933.1|325265_328631_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_013172.1|WP_164929831.1|312020_313436_+|hypothetical-protein	gnl|CDD|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	1.49685e-20

Protein sequences

>NC_013172.1|WP_012803929.1|317990_321023_+|hypothetical-protein
MSEPDGGQNPPQDPQSQGQEPQGPPPQDAQGQQPQWQGQEGQPAPEPSAPQPGTSAPQPGGPGQAPGGPALPPQAPYSAPQSGGQAPQGSPAPYGSPAPYGSPAPQGSPAPAPYGSPAPQGSPAPQPGAPAAGAAAGTAATAGMTPQELKQKLSSVGLVNPLPSLAVGGATYVGGIVLSVLTIVLIAIAAAVASIGNPVEAALETADMDPSEALSGVGSAVRFPFQLVAMAMLGSLGFSKTIEGETISASVRLLPGVITVVMVLLSFYGGRFVQKRQAAGQIGIWISSVLTGFAFALLTVLAALIFAQPVPVYGDISLRLHAAGFDAFFGAFFLITLALALGRISVRARPAWWPLVTDLTAGFKLALSHALIVTVLGVVVLTVGTTISALIDGETPPMLIVLLLLPLLGGYLFSFVTGLDMLSALSVNTSGPDLFGMMDGVYGNETASMFSMPWYAWLVGLLIGAIGLLLAALLWQHQRQVVPNNVVALGVSWVALPAAYFVGSLGLLLLARLSMTISYSGSFSDSEKIGMGAGLAAWTPLLALMAGVIVELLSRFVLPLVAPFIPAALLGWFRRPLAPALAAGTATAATAHAAGTAPTGAEDATAVNAEGIPTELPGGAPLGGDAAQNAAPQAAEDTSAYGTVPLGATGGALAVAGAAAAGGQAAEPTPLSPRARRLLIGGAVSVGSAFVIIIGVTVAFNVISSTVYSPEKKVEAYLSALQEGDASTALEISAPNVPTAQQALLTDAIAGAAEERISGYEIVDTEKGDDGAIITAKLTQDGVTSTRTFSVERSGRTAVVFPQWTMQETEYAHLEILIPEGATSVLVNEQEVPVESLAPEDGYATAAVLPGAYTVSVPAASEMITAEPGEVYVPADPDDWYELYAAPSYVISEAGVAEAQKQVDALLDECATSTEARPEDCPFGTYAYNIVEDSGAWTIDTYPTIELEEGQDGWRLSSYDTPGEATFTYQSEGWDDEITDETEEGEFTVSGEVALAEDGSLEVELGTGYW
>NC_013172.1|WP_012803928.1|316953_317808_+|hypothetical-protein
MTTLPADSHVHSEFSWDTGGPDSPARGTMEATCARAVRIGLPALFFTEHLDLEDAWFTDPADFADHERHLLDAEGRVAVPRFDADGYFESIERCRAAFPQLRIGTGLEFGQPHLRAEAARQQLDLDRFDRIIGSLHTLPVGERRHEPDTLFRRMPAEEVIRRYLAEVPALVAGDEPFEIVTHLDYALRYWPEEQEGPVDPRRFEEEFRTALRAVAESGRALEMNTRRLWPWMPQWWSEEGGCAISFGSDAHTAAALAHGFPEAMAMVEAFGFRPGPDPRDLWRR
>NC_013172.1|WP_012803927.1|315473_316913_+|sugar-nucleotide-binding-protein
MTELAVRTTPIPGLLVIDLPVHGDPRGWFKENWQREKMLAAGLPDLGPVQNNISFNQTVGVTRGIHAEPWDKYISVATGRVFGAWVDLRRGPSFGATYWHEITPDIAIYVPRGVGNAFQTLEAPAAYTYLVNAHWSAAAQEQYTFLHLADETAAIPWPIPLEQAELSAKDRAHPLLADVAPVPPRRTLVVGGGGQLGRALAAWWSRRGDVDVVAREHLDIADARSVAAFDFAPYGTIVNAAACTAVDASEAPEGRRTAWAVNVTGVGHLVEAARAHRATLVHVSSDYVFDGTIEVHGENEPPSPLGVYGQTKAAGDQLVATLPDHYIVRTSWVIGEGRNFVATMAALAERGIDPAVVDDQIGRLTFTEDLAAAIDHLLVARPAPGIYNVTGEGEPASWAGIAAEVFALSGHDPHRVTPVSTAEYYAGKDGIAPRPAHSTLDLAKIRATGFVPLDQLTALRDHLSSSHPAAPAEARLAAS
>NC_013172.1|WP_012803926.1|314422_315427_+|dTDP-glucose-4,6-dehydratase
MSTRHLLVTGGAGFIGSAFVHHVIAHTDDTVTVLDKLTYAGHRSSLEDLPSRRVRLVVGDVADAATVEPLVAAADAVVHFAAESHNDNSLSDPSPFLQTNLVGTYTLLEAVRRHGARFHHISTDEVYGDLALDDPDRFTETTPYNPSSPYSATKAGSDLLVRAWVRSFGVQATLSNCSNNYGPRQHVEKFIPRQITNLIDGIRPRLYGAGANVRDWIHAEDHSSAVLRILEAGESGRTYLIGADGEKSNKEVVELILRLMGRPDDDYDHVTDRPGHDLRYAIDATALREELGWAPRFRDFEAGLAATIDWYRENEGWWRPQKAATEAKYQLTGQ
>NC_013172.1|WP_012803925.1|313502_314426_+|glucose-1-phosphate-thymidylyltransferase-RfbA
MRGIILAGGTGSRLHPLTIGVSKQLMPVHDKPMIYYPLSTLMLAGIRDILVITTPEDSSAFQRVLGDGDRFGVNLQYTVQPSPDGLAQAFLLGEEFLDGEKAALVLGDNLFYGHGMGAQLRRHQDVDGAAVFGYWVNDPTAYGVVEMGEDGRALSLEEKPAVPRSNLAVPGLYFYDETVVDRARALTPSTRGELEITDLNRSYLEDGSLQVEVLTRGTAWLDTGTFDDLAAAGEFIRTVQQRQGLSIGAPEEVAWRMGYLSDDELRHRALPLVKSGYGRFLLDALEREIADRPLHLHPSAAAMRVTA
>NC_013172.1|WP_164929831.1|312020_313436_+|hypothetical-protein
MKKFEAADYVDWDWLPGAAAEIEVYLARLLTEASITAHAVDARSKSIASFQEKCALKEYDNPRQQVTDTVAIRLIMYSVTDQERAVELVRSRFVVKEDMNPGADKPPARRGYDCAHLVVTGELQDRSRDWLVAGGHLARYFDRFGGLEIQIRTVASHAWAEFEHSRRYKGVGYRKVSEHDRETIDQLFGAAADARSALDETFTAIDRVLANPSRAASLEESVDEVPTGEDGPAESELSCASESEGQLDAALMKNFLARRFPNDNEGSEAGVEFACELVRACGLSSIQEAASALSSIDSTEVRNLMSTTIAVTRVRRLDDELLAVFGEDYIRNTESIGTVSRRGDQLRWRFDRLRGKVTVKRSPVAFQILGDDCPDAVRVLKLPAARAVRELAGIVANRGGAQSIVMSGAISTDDDLPMSTRARPVRLEDGTNLWVATNLNRAASEALMSSIVDSAPALDLRVLRAGEPFLP
>NC_013172.1|WP_012803923.1|309515_311849_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MTTQTTPLPAATPVGYPRIGPDRELKKAEEAYWAGRIDHAEFARRTRELRRATRGRLAALGLSAAAAAPESFSLYDQVLDAALAVGIVPDRFASVLDADGAVDDDGLFALARGTAEKSPLEMTKWFDTNYHYLVPEIGPETELHLASTRAVELFTESLEDGAGTRPVLVGPLTLLLLAKAQDGAPEGFDPLDRLDDVVEVYAQLLARFAAAGAPWVQLDEPALAADQRVSATELAELLQRSLGRLAAGTDRPQLLVTTPYGGIGDLLPALLATGADAVHLDLTRGELPTVEQLAGVDTVQLVAGLVEGRSVWRTELPTAAARLAELRRRVTAAGGAPEEVAVSTSVSLQHVPHTLEAETSLPAELTATLAFADEKITELVTLAGDEVAPGSVDGPRSVPRTFEGVSVPAVRERAAAVTAADAERADYTVRAEAQRRALGLPDLPTTTIGSFPQIPEVRRARAAHRRGTLDDAGYEKAMKDEIARVISLQEELGLDVLVHGEPERNDMVQYFAEHLEGFATTEHGWVQSYGSRCTRPSILFGDVHRPAPITVDWATYAQSLTPHPVKGMLTGPVTILAWSFVRDDQPLGDTAAQVGLALRDEVRDLEAAGIRIVQVDEPALRELLPLRQAAHEDYLDWSVRSFRLATSGVQDATQIHTHLCYSEFNVVVGAIDALDADVTSIESARSRGEILEAVDPDSFPRGIGPGVWDIHSPRVPGAEEITEQLRRARAVVGPERLWVNPDCGLKTRGYAETEASLRHLVQAAREVRAEAGAPAAV
>NC_013172.1|WP_012803922.1|308577_309519_+|methylenetetrahydrofolate-reductase
MSATTTLPELERTAPVRHRPALSYELFPARSDVSFERLQETIAHLEATGPDYVSVTSRARHGNLARVIEVTEHVLAETSLRPLVHLTSIGSTRAQLTTIIHALLDRGVRGILALRGDQPEGHRLEDDEVPFARPLIELIRDIERERTATLAGGRVSIGVAAYPLRHPESPTTSHDTEVLVAKEKAGADFAITQVFFEPSVYCGLLARAEEAGIRMPIVPGLVPATNPRRLERLAAISGVEAPRELLHQLEIASDEVERRRIGVRFTVDLARRVLDAGAPGLHLYTFNSHADALDVLDHLDLDRWSATPQGDAR
>NC_013172.1|WP_164930108.1|307879_308332_-|adenylyltransferase/cytidyltransferase-family-protein
MSMRIGYAAGAFDLFHIGHLNLLRRAKQSCDVLIAGVVSDEMLREVKRIEPVIPTAERAEIVGNLRCVDQVHIETTPSKLDTWRDVGFTHFFKGDDWRGTPKGLLLEEQFGEVGVEIVYLPYTMHTSSTALRRALTAISSSTSLQTVGNS
>NC_013172.1|WP_012803920.1|306233_307676_+|sugar-transferase
MLSLPARRARRDDRVVVAALVAADVAVLAAACVLAIMIRGSLSFLGVSQALPDSLVASSVVIAGVWLASMLVFGASNPRVIGSGAEIYRGVLLGTVATVGVVGAVLFLADIPLSRPYFIVLFLVGPLLLLLVRAIARRCVNLARARGRLRAQVLAVGSTGHVRGIVRTLGREVWLGYDVVGAVAPVSDRHDDESAGVPILGDESRLLDLVREVQPDVVLFTAGSSASAEEFRRVAWELEELEVDVIVVPGVSEISGDRIRMRPVAGLPLVHMDLPRSRKALKKGKRIFDVVASAALLLLLSPVFAVIALCIRLGDGGAVIFRQERVGRSGEPIEFLKFRSMVLDAEARLAELEQLERDRGNVVLFKMSDDPRITKVGKVLRRYSLDELPQLWNVLRGDMSLVGPRPALPREVEGYDTDAHRRLAVRPGITGLWQVSGRSDLSWDDTVRLDLFYVDNWSFMQDLLILVRTVRAVLASRGAY
>NC_013172.1|WP_012803931.1|322473_323691_+|glycine-C-acetyltransferase
MYTDLKDQLTAELTEIEEAGTFKHERVITTPQSGRVMAGPVGRDGTEVLNFCANNYLGLADHPDIVSAAKQALDERGFGMASVRFICGTQDLHLRLEQAVTDFLGTEDTILFSSCFDANGAVFGPLFGAEDAIISDELNHASLIDGIRLSKAARFRYRNADLEDLRAQLEAVAALRDGKGARRTVIVTDGVFSMDGYLAPLEGICDLAEEFGALVMVDDSHAVGFMGATGAGTPEHFGVSDRIDIYTGTFGKALGGASGGYVSGRREIVAMLRQKGRPYLFSNSLAPSIVAATLTALELVEGSAELRGTLFRNAELFRRRMSEEGFELLPGEHAIVPVMFGDAALAGRIADAMLEHGVYVTAFSYPVVPQGKARIRVQLSAAHTEQDVEAAVQAFVASRAAVQEG
>NC_013172.1|WP_012803932.1|323740_325045_-|MATE-family-efflux-transporter
MDREILVLAIPSLGALVAEPLFLLADSAFIARVSTTSLAGLGLASTVLTTIVGLAIFLAYSTTAAVARSFGAGRIREAISRGIDACWVALAVGAAAALLLLVAGGPLLAAFGPSPEVLAEALIYLRISALGLPAMLAVQAATGLVRGLQDAKLPLVVAVGGALVNIPLNWVLIFGLDLGIAGSAIGTVLSQWGMAAVLLGVIIRRALRETISLRPHLTNLVAVGRDAVPMFVRTLGLRVVVVTATVVATRLGDVQLASHQLATTVFTVLSLALDSLAIAGQALTGRYLGASDPGTVRAVTRRLMTWGVGGGAVVAVLLLAASYVVPELFTPDVAVQENLRAALWILVITQPIAGYVFVLDGVLMGAGDAPYLAKVGSLIAVAIMPGAVLVAWWAPAGPLGLALLWLACNFLFMVLRAISLGLRVRTDDWMRLGG
>NC_013172.1|WP_012803933.1|325265_328631_+|efflux-RND-transporter-permease-subunit
MNRLATLSLNNRSFIALVCIAVSIIGVFIMTTMRQELIPSVSLPQIQVMTTAPGSSSEQVQDRITGPVEQSLSGLENVEGTSSTSEAGVSIVTVELTYGTDVARSSNQVDAALSGIEDDLPEDADPQVMAGGTSDLPAVVLSVSSDLDPSELSSRLESSVTPELERVSGVSSVAVIGAPEEIVRITPDEDALAENGLTEDDISTALDANGLSLPGGSVVDGDRTLDVVLGQSLDSIESLEQIMLMPAEDGGQEEPQQGPDGQPLPGTQEQQPAEPVTLAEVATVERTTQDATSISRTNGRESLVLMVTATVDGNVVDVSEGVEGVLAESLSSVGGNAEADVVFDQAPFIEESILALAEEGLLGLLFAVGVILLFLRRVRPTVVTAISIPTSLLIAFIGMYVTGYTLNMLTLAALTISIGRVVDDSIVVIENITRHLAYGKTRRRAILDAVGEVAGAITASTLATVVVFLPIAVVAGMAGELFRPFALTVGIAMLSSLLVALTIVPVLAYWFLKVPKGHEDVDPDDAAQVTAIRDAAEAEEERSWLHRMYAPLLRTTLDSRPRRLVTIAVSVLVLVGTAFLYPLVNISFLGDTGQNIASLSQTLPAGSSLEQSSQKATESEDALLELDGVQTVQTTIGGGGMGFGGGGENEVSFSITTDPDADQEALLDEMVATLEDLPDPGTIEAADIASPTGSNSVDILITGPTTEDRQAANDAILAELDPLPEGVSEVTSDLQADQPTAVVTVDREAAAQAGLTEEAVIGMVAQQMYPGAIGSITLDDNELDIYVAGGESVDTYAQLQDLELMGTIPLQDVASVEEELSRPSIATQDGLETVTVSLTPATEDVGAASEAANDAIESADLPEGVEASLGGTAADIDETFGQLGIAMLAAILLVYVLLVWIFKSLVQPLILLVSIPFAATGALGLLIITRVPLGLPSMIGLLMLVGIVVTNAIVLIDLVNQYRRKGMGLDEALHLGAAKRLRPILMTAAATIFALVPMALGLTGNGGFIAQPLAVVVIGGLVSSTLLTLVIVPVLYRLAEGPGERKRLKEEAHQARLREERERAEAEKRSHREAEARARQRELGASAVVDERPASPVPGHRRSLKDRGGIVGMMKRRLGRG
>NC_013172.1|WP_012803934.1|328778_329750_+|glycosyltransferase
MREPQNIVVGLATFRRPELLAGLLPRLLEQIEQAAAALPEGAELGIVVVDNDPAGSAREVVEAAGGPRVRYALESVPGISSARNRVLDEAHDADVLVFLDDDETPHSDWLAHLLRTHREHDADAVSGPVHAVFEGGADPWVAAGEYYLGQRREGFPTGTVLRRAATNNLLLDMAAVRRAGLRFDERFGMSGGEDSLFTGQLTAAGGRIVLCAEAVVDDLVPRERNTRSFNLARRRAQAATHVRVDQELASSRGERARNAARWLVTGSGQLAKGGVLAVLGRATGDLRLRAQGESRVASGLGVLGGCVGVVSSPYARTRARAGS
>NC_013172.1|WP_164929833.1|329784_330378_-|hypothetical-protein
MAGECARRDGLHVLADARRIEVVREDGSPAEPGETGDLVITDLRNRVFDLIRYPTGDRGILRAAPCPCGRSLPMIEARQGRTIDVLHLPSGAALAHRLTAMFSAHPEAVRLFQIHQQADFSLTVRVVGGDGPEARRHVEAAVEGLRERIRRAVPVRVEHVESLPYTGGKTKYILSDVPKPWPLPAAPPLSTPPPRSV
>NC_013172.1|WP_012803935.1|330497_330767_-|hypothetical-protein
MGLRAASFAVKSSTVRASAGRFHRLQLAHERMSPAALSALQDALARDIATTAMRKSPYYRSTYGALRIDPGGSRTRRRGPRSRSSTAPP
>NC_013172.1|WP_164930109.1|330826_331951_-|glycosyltransferase
MRGGRRQAFTEPRGLWAAVRGLLAGAAQVLRRPERGSRRQPGIPRQPAALPHSGEGATSARALEPAEGSTVRVTVAIPTFRRPDQLAALLAALPARIAETPDAEIDVLVIDNAPEGSARATVEAAPAGVRYVHETTPGISAARNRALDESRSADLLAFLDDDEIPLAGWLSSLVEVWRGHRSAAVAGRVISVFHEDTDPWIIASGTFRRPQRATGTSLRTAAAGNLLLDIRQVQALGLRFEGSLGLSGGEDTLFTRQLVERGGTIVWCNESAAEDHVVPSRLTRDWAVQRAFSAGNGWANVNLLLAPSSTRRLALRGQFLLGGGARIAVGLARHRYGRASGHLVHDARGTRTFHRGRGMLAGARGHLYQEYARN
>NC_013172.1|WP_012803937.1|332960_333689_+|CDP-alcohol-phosphatidyltransferase-family-protein
MIVESYRQLAYAQKGHARGAPAYSVYVNRRLGRALAAGAHGLGLTPNQVSLVSAAHSFAAILLIALVPASIPAGFFIALLLVLGYAWDSADGQVARLRGGGSAQGEWLDHFIDTLKISSLHVAVLIGLFRGLPEGAEVLLLIPLAFGIAATASFTAMLLNDLLKGKHAVASTHERGGGTLKRSLLVLPTDFGLVCLVFVLWGWPSVFLLGYGALAAVSIAFLAMAAVKWFREMGSLGSGRER
>NC_013172.1|WP_164929834.1|333678_334287_+|hypothetical-protein
MSAELLLLVCAANVCRSPLAELLLRRELDGLSEVRVESAGVGASDGARICELVAERHADAPWVRAAQEHRSRSLTPELLASAALVLVADREVRSEVVRMSPGVRDRIFTLRDAALLIDSFEIEEPARRVGRVSRMGIHLNRHRAVRGPQSPARRRLWGRREEGPSSIDDGHNSSLRHHHAALEAVSSTTSVVAAGLMGGPIG
>NC_013172.1|WP_174265943.1|334782_335151_+|hypothetical-protein
MPIELPTDVVVSLADISTTTVEAETPGEYAGAAVVVTVHVLNDSTQAQDVGSAVVSLGADGGEVGVPTWSAPYSPLEGEVAAGETAEGTYVFMLDPANGRSVTVRVNYSAGEPLAVFAGQTS

Crispr_ID: NC_013172_3

• CRISPR_ID: NC_013172_3
• CRISPR_location: 853306-853388
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_013172_3

Consensus_repeat	Method
CCGGCCCACGCGACGGCCCGGCCGGACGC	CRISPRCasFinder

spacers of NC_013172_3

>3.1|853335|25|NC_013172|CRISPRCasFinder
GCGGTGGCCCGGCGCAGGCGGCGGC

CRISPR arrays and Neighbor proteins around NC_013172_3

CRISPR arrays

The CRISPR arrays of NC_013172_3

>merge|NC_013172|3|853306-853388|CRISPRCasFinder
CCGGCCCACGCGACGGCCCGGCCGGACGCGCGGTGGCCCGGCGCAGGCGGCGGCCCGGCCCACGCGGCGGCCCGGCCGGACGC

>NC_013172|3|3|853306-853388|CRISPRCasFinder
CCGGCCCACGCGACGGCCCGGCCGGACGC	GCGGTGGCCCGGCGCAGGCGGCGGC
CCGGCCCACGCGGCGGCCCGGCCGGACGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_013172.1|WP_012804374.1|845152_846316_+|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NC_013172.1|WP_012804371.1|842879_843506_-|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_012804378.1|849668_851912_-|alpha-galactosidase	unknown	unknown	gnl|CDD|307952
NC_013172.1|WP_012804385.1|861683_862478_+|thioredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|372611
NC_013172.1|WP_012804386.1|862712_863963_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_013172.1|WP_012804379.1|852079_853291_+|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|181738
NC_013172.1|WP_012804373.1|844308_844995_-|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_012804370.1|842000_842636_-|DUF47-family-protein	unknown	unknown	gnl|CDD|224310
NC_013172.1|WP_012804372.1|843629_844286_+|PH-domain-containing-protein	unknown	unknown	gnl|CDD|371225
NC_013172.1|WP_012804389.1|865371_865980_+|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379163
NC_013172.1|WP_012804383.1|858590_859268_-|AIM24-family-protein	unknown	unknown	gnl|CDD|376704
NC_013172.1|WP_012804387.1|864199_864877_-|uracil-DNA-glycosylase	unknown	unknown	gnl|CDD|235376
NC_013172.1|WP_012804377.1|848731_849646_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_013172.1|WP_164929876.1|856251_858555_-|circularly-permuted-type-2-ATP-grasp-protein	unknown	unknown	gnl|CDD|379601
NC_013172.1|WP_164929877.1|859473_861534_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_013172.1|WP_012804380.1|853567_855034_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|215457
NC_013172.1|WP_012804375.1|846373_847768_-|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270303
NC_013172.1|WP_012804388.1|864971_865310_+|DUF3263-domain-containing-protein	unknown	unknown	gnl|CDD|378688
NC_013172.1|WP_012804376.1|847778_848717_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_013172.1|WP_012804381.1|855239_856259_-|transglutaminase-family-protein	unknown	unknown	gnl|CDD|224224

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_013172.1|WP_012804374.1|845152_846316_+|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.20142e-39
NC_013172.1|WP_012804383.1|858590_859268_-|AIM24-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.23551e-40
NC_013172.1|WP_012804388.1|864971_865310_+|DUF3263-domain-containing-protein	gnl|CDD|378688	pfam11662, DUF3263, Protein of unknown function (DUF3263). This family of proteins with unknown function appears to be restricted to Actinobacteria.	9.02921e-22
NC_013172.1|WP_012804385.1|861683_862478_+|thioredoxin-domain-containing-protein	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	8.33988e-12
NC_013172.1|WP_012804386.1|862712_863963_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	6.17465e-11
NC_013172.1|WP_012804379.1|852079_853291_+|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|181738	PRK09265, PRK09265, aminotransferase AlaT; Validated.	0
NC_013172.1|WP_012804372.1|843629_844286_+|PH-domain-containing-protein	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	0.00612932
NC_013172.1|WP_012804370.1|842000_842636_-|DUF47-family-protein	gnl|CDD|224310	COG1392, COG1392, Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism].	4.17769e-06
NC_013172.1|WP_012804378.1|849668_851912_-|alpha-galactosidase	gnl|CDD|307952	pfam02065, Melibiase, Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.	2.62696e-131
NC_013172.1|WP_012804389.1|865371_865980_+|LytR-C-terminal-domain-containing-protein	gnl|CDD|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	1.28703e-09
NC_013172.1|WP_012804377.1|848731_849646_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.70785e-82
NC_013172.1|WP_012804387.1|864199_864877_-|uracil-DNA-glycosylase	gnl|CDD|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	1.17732e-117
NC_013172.1|WP_164929876.1|856251_858555_-|circularly-permuted-type-2-ATP-grasp-protein	gnl|CDD|379601	pfam14403, CP_ATPgrasp_2, Circularly permuted ATP-grasp type 2. Circularly permuted ATP-grasp prototyped by Roseiflexus RoseRS_2616 that is associated in gene neighborhoods with a GCS2-like COOH-NH2 ligase, alpha/beta hydrolase fold peptidase, GAT-II -like amidohydrolase, and M20 peptidase. Members of this family are predicted to be involved in the biosynthesis of small peptides.	4.31893e-63
NC_013172.1|WP_164929877.1|859473_861534_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.51832e-67
NC_013172.1|WP_012804380.1|853567_855034_-|FAD-dependent-oxidoreductase	gnl|CDD|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	1.22827e-128
NC_013172.1|WP_012804375.1|846373_847768_-|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.49083e-58
NC_013172.1|WP_012804376.1|847778_848717_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	6.32369e-71
NC_013172.1|WP_012804381.1|855239_856259_-|transglutaminase-family-protein	gnl|CDD|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	4.52619e-41

Protein sequences

>NC_013172.1|WP_012804379.1|852079_853291_+|pyridoxal-phosphate-dependent-aminotransferase
MIFTQSSKLRDVCYEIRGPVPAEAARMEAEGHKILKLNIGNPAPFGFEAPDEILVDMIRTLPTAQGYSDSKGIVSARRAVAQYYQTKGMPDMGLDDIYLGNGVSELIQMTCQALVDDGDEVLVPAPDYPLWTASVALAGGRAVHYRCDEEQQWWPDVSDIADRITERTKAIVVINPNNPTGAVYPEHVLREIVEVARKHGLMILADEIYDKILYDDAVHTHIAKLAPDLLTLTFNGLSKAYRVAGFRAGWMALYGPKEHATSFIEGLDVLSNMRLCPNVPAQHVVATALGGHQSVQELLLPGGRLREQRDVAYEGLSAIDGVSVVKASGALYMFPRIDREMYRIEDDEQFAYDLLRSKKLLVNHGTGFNYPSPDHLRLVTLPPVDLLADAVDRIADHLASIRR
>NC_013172.1|WP_012804378.1|849668_851912_-|alpha-galactosidase
MSPRRIPVDTTVTAPRPGETRRLHLRAAGVSVVLDVTEGRLPAIAHWGADLGALGPAGLDAACETAVDAVPQNAVDVPVRLGILPQQSDGWIGRPGLSGSRPDGSGWVTRLVTRGIELDGQALTAAHAETGPAAVRFDLADEEQGLALDLEVELLPTGLLRLRAGLTNTGRTPYALDELTLAVPVPDVAEELLDFAGRWTKERTPQRRAFTTGTHLRENRRGRTGADAAHVLHAGRPGFGFREGEVWGVHTAFSGNHRHLAEQVNTGRRVLGGGELLLPGEVRLEAGERYQGPWLYASYGEGLDAVASRFHRHLRAREHHVDRRRPVTLNVWEAVYFAHDLARLTDLADRAAALGVERFVLDDGWFGSRRDDFSGLGDWVVSEEVWPDGLGPLIDHVTGLGMEFGLWFEPEMVNEDSDVARAHPEWILGPSPTALPLESRHQQVLNLSLPEAYEHVRTQMLDLLDRYDIGYLKWDHNRDLLEAATRATGRAAVHEQTLAAYRLMDELKAAHPGLEIESCSSGGARVDLEVLEHTDRVWVSDCIDPLERQQMNRWTSQLIPLELMGSHIASGRSHTTGRLHTLDFRAHSALFGHLGIEWDLAEASEAELAELRVWIALYTQQRELLFRGDLVRADRGESMLWLHGVVSPEQDEALFSLSSVGRSATSQEPRLCFPGLDAAASYRLRPVLPGELPSNFAPPAWLQRALDEDGVTVPGGVLTRSGLSAPLLDPEQGMLFALETTTSTSPR
>NC_013172.1|WP_012804377.1|848731_849646_-|sugar-ABC-transporter-permease
MTTATTSTRSAPPRRRRKDDRKLALLFIAPASVGLLLFLVWPLLTGIYFSFTEYTTLTPPEWVGFENYRAMLADPVFWNSLKVTIWYVILNIGVQTVVALAIAVLMQRLTQSTILRSLVLAPYLVSNVVAAIVFLWILDTQLGIFNIFLQWVGFDPVAFWASETWVIPTVALVNVWRHMGYTALLLFAGLQSIPTFLYEAARTEGAGEIAMFRRITLPLLRPILALVLIMTIIGSFQVFDTVSVTTQGGPADASKVLQMYIYENAFGQYQFGYASALSVALLLILMVITFAQYRMSNAGQSDLD
>NC_013172.1|WP_012804376.1|847778_848717_-|carbohydrate-ABC-transporter-permease
MTTTTSVTAAETARPPAHRPRAPFPWGKIVAWAVMLVFLFLTVFPFYWMLRTALSSNNALATDPASLLPVGLNTGGFERVFGLQDVETAISQGGSGASINFWRYLLNSVIVATVITVVQTFSCAMAAYAFSRLRWRGRETVFMIFLGSLMIPQIFTLLPNFILIKNLGLVDTLLGIMLPTLFISSFAIFFLRQFFNNISREVEEAALIDGAGKVRVFFTLILPMASAPLATLALLTYMTAWNEYFWSLMVSYTDQSRVLTVALGVFRAQAPGTGPDWSGLMAATLVAAAPMLILFALFAKKIVNSIGFSGIK
>NC_013172.1|WP_012804375.1|846373_847768_-|sugar-ABC-transporter-substrate-binding-protein
MIDPTHRAHPHRPGLTRRRLLQGSAAVAAGAVGAGALSACGESAAPAGATQIDYWLWDANQLPAYSAAIDLFMEQNPDIYVRITQLGWDDYWTKLTASFVAEAGPDAFADHLARFPEFVNLGVIAPLDDLAPLADITADRFQEGLQELWSDREGTRYGIPKDYDTVAVMYDKNLLAEEGLAPEDLEDLDWNPEDGGSFEKMLARLTLDTNGVRGDEEGFDPTSIARYGLAADPGIDYTGQTSWSPFALSTGWTFTEAETWGTSFQYDDERFTATMDWYFGLVDKGFFPPFGTFGDSSPAQSQLQAGSAALATAGSWMISTFANMEGMELGIAPLPAGPIGTPVSMFNGLGDSISSQSQKKEEAARLIAFLASDEAQRLIGQRAPFFPATDAGTEAAIESFAEDGLDVTPFTDRVTNGETGLYPLVENSASIMSIMQTAFDQCWLRRIDGADFASFNDRVNALFD
>NC_013172.1|WP_012804374.1|845152_846316_+|ROK-family-transcriptional-regulator
MQGDEHTATDATTVTSLGGDSSRAVYRDLLRFGPRSRSELSQRLGLSAPTVTRVSRDLLERDLLHTLTAVPRTKGRPHEPLDIEENRGPRFIGVKVTADEVHAVVTTVRANVLEELVLPLSSTAPETLLETILLAAEAIIAAHPHVVGIGVGMGGLVAERRTVIASHLLGWTEPVELAAALEERVHLPVVVENDLIAMVSGLHWFGLGRSYDSFAVLTVGAGVGIATVIDGRVVRGRRHMAGLTGRVPVASAPDGSPIPVREVASTPAMLRRAHARGVLTGSEGIEELRALITAGEEGALEIAAEMARALAVTAVGLVAVVDPEAIVLDGETVDLLRAADPVFEDTLADGIAGRQQELVVRTLSGTFDEWARGVAVIAVQEFVGVAP
>NC_013172.1|WP_012804373.1|844308_844995_-|hypothetical-protein
MSETTAAATDEQATIYTAYEIDFMLGLRDTENGRITREQVGLRSAPEAAREFVTAAVTSGLRARGKVERSEDGQWLLGEEGQVVATALTAADRWLGIALAEGEAMRMAFIIKANDAIVMLTQDELDSFVVTALPGPEQVPASVADIVQAFLDGGNERTVSLRRTDLSAADDPIPLMFHVEQGGDRKIGHLPLDEEGILQVSDLPADGVAEAVRALWEEGASRAPGASA
>NC_013172.1|WP_012804372.1|843629_844286_+|PH-domain-containing-protein
MTIPRQIGPETGPRTALPDYRRSSATVERMVSDLRRRSRGNRGASRQVRALLPAAATRDTALRAVLSAALLGGALVPAVAMVLLLLALEDGRSPGLGLLIVLLALAGSGLILLLLGLRFGIVALGTARARVEIADEGLYVVGGLRSRSVPWRDIVAVDSGVVHPVHWHTAALRLRDGSRVVMPAFDRHLWTYGQPSGQDIRTLRTELRRRELEARRPF
>NC_013172.1|WP_012804371.1|842879_843506_-|hypothetical-protein
MSSHGSSAPRFRRPAPLYDSVAATIPGEPDPATSSDLAHDSARALLDGVFHSSDPEVVERVVTLAEEDGLADLAALWSNAPAATLPGALWRLYVLHTWSQRNADDLLRRYRAGSRTVPGLRYLSGLAEPPDVDEVHRTMDAILRGAFTGDLALALRRAGAVATIVAHGTAHLADEDADDDRTRQAERLLSTGEALTTAGRHAEAGQLD
>NC_013172.1|WP_012804370.1|842000_842636_-|DUF47-family-protein
MVQFLSRLFPQRTERPLYDLFAELAELLVQAADTHSRLLGHGYRERTRIAPRLHEQATVAEELCRRIAQRLAHSLITPYEAELLYDFALTIADAVDAMEHTAELLVISQVGTLPTPLMDAAKGIERAAELTVAATWELARVRQLGEYYEQVRKLKRQGDRLVRRALGELYTRGGSTQELLPLHDVAESLRETILLQERIARIADLLRVKDA
>NC_013172.1|WP_012804380.1|853567_855034_-|FAD-dependent-oxidoreductase
MSSSQQPFRLAVIGSGPAGVYAAETLLRSPQVKNGELEVSIDLFDRFPAPFGLIRYGVAPDHPRIKGIITALHRILGRGDIRFLGDVEFGTDLTAEDLRLHYDAVVFATGALKDAELSIPGIELEGSHGAADFVAWYDGNPDYPRTWELDAEQVAVIGNGNVALDVARVLSKSADELLRTEIPQNVYEGLQSARTTDVHIFGRRGPAQTKFSPLEARELAHPKGLQVVMDPRDVEQITEAEWEAIKADKRTDQVVQTFVGWLEEQQRREAAGEEPTDREGGPVRRRLHMHFWHRPVEVLGEDGTVTGMRFERTRLDAEGNLEGTGEMVDYPLGAVYRAVGYHGSELPGIPYDPRRGVIHNVAGRVTEADGTVIPGVYANGWIKRGPVGLIGATKSDAIETIASLLEDIESGTLAPAPEREEDAILRLLEDRGVQYTTWDGWMALDEHEKSLGAAAVDADGEPRARIKVVEREEMVRVSRDGVQQPSHV
>NC_013172.1|WP_012804381.1|855239_856259_-|transglutaminase-family-protein
MSENATTETTGSAPRRPLIPLRHEGAEAVEPMLYRVHHLTSYRYAKPVSRNFGRAHIEPRATPHQRVLSHEVVVDPAPARLTAHTDFYGNSSTYLLVDTPHTQLDVHSHAQVTVAERRYPLEPMSRPWEQCTPEHWGSVLPDSGLDFVHPSPRIPAGTAAQEISAAVFTPGRAIGECLSALTALIHSDFTYDSSATTVSSTLEEVLAARHGVCQDFSHVGVAAVRAAGLAARYVSGYLRTAPSAGGSLGTAPVGEMIGSAASHAWLSVLVPGTGWVDIDPTNRTFVDQRFVTTAWGRDYADVPPLKGIVVGPPGATSTLDVAVGVVPDSPAPPTTASPA
>NC_013172.1|WP_164929876.1|856251_858555_-|circularly-permuted-type-2-ATP-grasp-protein
MTSPPPQALVDELDALGPRGRRRAAASAAAMFAGDVSATAPVIDPVPVVLDAEAWSQLSAGLIQRMRLLDALYADLYGPRTVLAAEVAPVAQLLQDPGYLRAAVGIPARGNHHLFAVTSTVTRTAEGSWVVLEDAVDVPDGAGTTLELRRVLSRCAPTLYRSTPLRRLHPFFDALRTSLHQRTRAEGRAGRTVVLTKDAEDPLRAFDHSWLANLLGAPVVSAGDLRTGSGTLTLRLPGLDSAAGDAVDALLRLVPSRLVDPLDLGPTPLRGVTGLVEAARCGDVEIFNPIGAGLLENPDLRTALPDLCRQLLHEDLLLRPAGPDTAEGGWLGLDPAGGDALVERPVRLRLLVMRTEDGFDVLPGGIGLTADDGPAALKDVWVTVPETAAVPARSAAQADAAALDSATPRDVLTTYPAMTRSIGSDLFWFGRYLERVDATARLLRTVLDTVNDLDSEPSPSARTAQSVLLGAVTEVTTTYPGFPALDLRDRETVRTEIESLLTDRSRPGALAQSYAALAHTTRTLRDLISDDVWPVIARMNQRLRSLGGQDAPPLEQGLTEIVDGCLTLSGAVADSMPRNLGWDLMEVGRKIERTSSLLALLRALLGRRRTRAAEARIAGAVALITESGASYRRSYHAAVQPELLMELLLSDTTLPRSIAFQLDRLGQTLDRLPEVAPTPELRAPLTALRSRLSSWQPQTMLRPLDTGAEGDAGAGAGAHADAVLGAPTALLEEADAALETLRELATALENRFFRPSESASRWGIDDV
>NC_013172.1|WP_012804383.1|858590_859268_-|AIM24-family-protein
MRSNLFDASNQERQTTDRWALQSHKMLRCALTPEAPEIISAAGAMVAYQGQMDFSYQGSGGGMKLLKKMATGEGGNMMRTRGHGEIFYARQAEEIFLIQLEGDALTLNTRNMLAFDSSIQWDIRSLGGAGFMAGGLFNLFLQGHGMVAVTSDGPPMLLDCSQQPTFVDPQAAVCWSANLQPQLKNDFKMGSLIGRGSGESFQLGFHGPGFVVVQPSEGMPAASGS
>NC_013172.1|WP_164929877.1|859473_861534_+|protein-kinase
MVPSRTPRRAARDPRLSALAEDSGYEILGRIGAGGMGIVYRAHDADGNDVAIKLLRHEISDDARARERLAREVAAQKLVRNDNIVRILDAELDSPDAFVVTEFIPGPTLEDAVRAHGGLHPEAVREIGLVMGETLRQIHAAGVIHRDLKPSNVMLRGATEQDLTGFDLDGDRLDPVIIDFGIAIAAEESRLTSTGLVMGTAAYLDPEVIRTDHAGEAGDWWAWAALIAFAATGREPYGSGRADLVFLRAERGEIDIEGVPSELGAWLRSALRSEPAQRPDPAQLLERLAALDLSLYDDPGETELLDAASRTAVLPVASGGSADAAAAGAAGAAGSAAAGTADAPDGAERSDGPGADEDGEATTALPVEDPAERTEVLPTLSTPAEEPTHALPRVTTPEEPVTEALPVTGPPTRALPVVPPAAGASATAPHWAPQPVPHPVAQQAPYPVAPQAPHQVAPQQAIAPHPQWDPAHPPGMAGPVEGYGPWPEPPPRRPVLVWLGHLLLIALAGIAPYVSLAALLLLGGLARVWERSHRAVTTQRMRGATGSGPSWRAGLASPFRMAVGLLETALQVLFPLILGVLVGFAFDAGWTLLQGSAPPDSAAFVLAMAITLLITWVGLGSGTTRNGAHRMLDAAAPDRFWSGVMLVLLLLLLGAVSLTLLARSGMVDYFPFPGGPRLDDLALWRR
>NC_013172.1|WP_012804385.1|861683_862478_+|thioredoxin-domain-containing-protein
MAASGPSPSAQQRREAQREALRTQRQAELSRQRTVRTVVIAAITVVALVIAAGLGVLVYRAMQPAGPVAVPEGMSEDQPYLSFGAPEDSGKPVLEMHLDFMCPICGQFEEINGEDFQEIIESGEATVHLVPRRFLDPQSTTGDFSTRSANALACVYDESPENALTFQQLLFANQPAEGSAGLTDEEIWGYAQEAGASEEVQECMSSGTYEPWVKKVADPHGEETGGGTPYVEIDGTSFTGWQEPGALREAVLAAGGEASDGGEG
>NC_013172.1|WP_012804386.1|862712_863963_-|hypothetical-protein
MAEPRSAAQEAGDPSTSPERLLELTEKHPQLQRLIVLNPSCPEVARQWILATNPWAKQAYDARGEAGEAGEASEAAPEEPSDAAEPPTAEESDHEEDPAEVSVWGDLGSAASPEPEASDTGGTSTVRIAQNAPVVPLGPAPSSPAESSPAAAQPSPASPAQAPGATPPPAGPAPAPASAAAAQEPWTYDAPPAPGAYDAAAAYGAAPAAATAATAAPLPAAEPEQDEDSGSTRRAWIACGGCLLLAVVLLIVMALVGRAWLAGDDDEGYQRDSSTTAAESTPAEEPSEEPTEEETEDPVSPAPDDAQEMTEVRSPTGNISCQLEEDSVACSVLDRDFSEAGLEDCDNGPFSLEVADGDAERACGTSFLSESGPTLEYDESAAYGDMACTSRFDGMTCWNTLTGKGFMVNRATYETF
>NC_013172.1|WP_012804387.1|864199_864877_-|uracil-DNA-glycosylase
MPTPLPEIIAADWAEALAPAEDRLHELGDFLRAEAAAGRGYLPAGDQVLRAFTRPLSEVRVLIVGQDPYPTPGHPIGLSFAVDREVRPLPRSLGNIYAELESDLGIPRAPHGDLTAWQDQGVLLLNRVLTVMPGAPASHRRRGWEEITELALRALVARGGPLVAILWGRHAQSLIPLLGDVPHIASAHPSPLSASRGFFGSQPFSRANTLLEQQGAAPIDWRIPA
>NC_013172.1|WP_012804388.1|864971_865310_+|DUF3263-domain-containing-protein
MPIDPARRDADATARPGAEVPDPTPAPAQDGLSDRDRRILALEGRTFRYVGAKERAIREEIGLSKVAYYVRLNALLDEPAALRAAPSVVHRLRGRRTSEDGPSGADGTHRVA
>NC_013172.1|WP_012804389.1|865371_865980_+|LytR-C-terminal-domain-containing-protein
MADSQYPYPPDRFDDEADAVSFHGAHRAELPFWRENLLYIIIIGAAAVLLIVLLFFIGSMGGGGDDRAEDPTSAAASEEAAGEESAEEGEGEASEEPAPEADKSTPVLVVNAGAINGLAGTWSDELEGEGWEDVSVTTADNAQQEPVVFYRAEEDAGTAQALAELVGAGEARQSDEYDAAVTFVAVNEPGEDTGGEDSGDEG

Crispr_ID: NC_013172_4

• CRISPR_ID: NC_013172_4
• CRISPR_location: 1157587-1157717
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_013172_4

Consensus_repeat	Method
CCGGGCAACAACCCCTTCGCCAGCTCGCAGGGCATGCCCCG	CRISPRCasFinder

spacers of NC_013172_4

>4.1|1157628|49|NC_013172|CRISPRCasFinder
TCCCGGCCGCAAGCCGGGCCAGGGCGGTCCCCGCCCGGGCGGTCCCCGT

CRISPR arrays and Neighbor proteins around NC_013172_4

CRISPR arrays

The CRISPR arrays of NC_013172_4

>merge|NC_013172|4|1157587-1157717|CRISPRCasFinder
CCGGGCAACAACCCCTTCGCCAGCTCGCAGGGCATGCCCCGTCCCGGCCGCAAGCCGGGCCAGGGCGGTCCCCGCCCGGGCGGTCCCCGTCCCGGGAACAACCCCTTCGCCAGCTCGCAGGGCATGCCCCG

>NC_013172|4|4|1157587-1157717|CRISPRCasFinder
CCGGGCAACAACCCCTTCGCCAGCTCGCAGGGCATGCCCCG	TCCCGGCCGCAAGCCGGGCCAGGGCGGTCCCCGCCCGGGCGGTCCCCGT
CCCGGGAACAACCCCTTCGCCAGCTCGCAGGGCATGCCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_013172.1|WP_012804645.1|1147893_1148769_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|225928
NC_013172.1|WP_012804659.1|1164778_1165048_+|30S-ribosomal-protein-S15	unknown	unknown	gnl|CDD|180170
NC_013172.1|WP_012804653.1|1156648_1156954_+|YlxR-family-protein	unknown	unknown	gnl|CDD|377288
NC_013172.1|WP_164930168.1|1153646_1154822_-|DUF4439-domain-containing-protein	unknown	unknown	gnl|CDD|373114
NC_013172.1|WP_012804657.1|1161746_1163270_-|L,D-transpeptidase	unknown	unknown	gnl|CDD|341130
NC_013172.1|WP_164930169.1|1160712_1161612_+|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl|CDD|235113
NC_013172.1|WP_012804647.1|1149705_1150299_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379324
NC_013172.1|WP_164929901.1|1165260_1167516_+|polyribonucleotide-nucleotidyltransferase	unknown	unknown	gnl|CDD|131743
NC_013172.1|WP_012804661.1|1167679_1169020_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_013172.1|WP_012804646.1|1148788_1149625_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_013172.1|WP_165446567.1|1150310_1151636_-|hypothetical-protein	unknown	unknown	gnl|CDD|225922
NC_013172.1|WP_012804662.1|1169159_1169930_+|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl|CDD|234595
NC_013172.1|WP_012804652.1|1155521_1156508_+|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl|CDD|237061
NC_013172.1|WP_012804644.1|1146726_1147887_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl|CDD|234737
NC_013172.1|WP_012804663.1|1169960_1170362_+|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_012804651.1|1154857_1155520_+|ribosome-maturation-factor	unknown	unknown	gnl|CDD|234627
NC_013172.1|WP_012804655.1|1160149_1160659_+|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl|CDD|234787
NC_013172.1|WP_012804649.1|1151848_1153633_+|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236405
NC_013172.1|WP_012804664.1|1170392_1170707_-|AzlD-domain-containing-protein	unknown	unknown	gnl|CDD|377512
NC_013172.1|WP_012804658.1|1163616_1164633_+|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl|CDD|235536

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_013172.1|WP_012804645.1|1147893_1148769_+|GNAT-family-N-acetyltransferase	gnl|CDD|225928	COG3393, COG3393, Predicted acetyltransferase [General function prediction only].	2.21383e-16
NC_013172.1|WP_012804659.1|1164778_1165048_+|30S-ribosomal-protein-S15	gnl|CDD|180170	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed.	4.45524e-52
NC_013172.1|WP_012804653.1|1156648_1156954_+|YlxR-family-protein	gnl|CDD|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	6.43792e-26
NC_013172.1|WP_164930168.1|1153646_1154822_-|DUF4439-domain-containing-protein	gnl|CDD|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	0.00430373
NC_013172.1|WP_012804657.1|1161746_1163270_-|L,D-transpeptidase	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	3.29889e-34
NC_013172.1|WP_164930169.1|1160712_1161612_+|tRNA-pseudouridine(55)-synthase-TruB	gnl|CDD|235113	PRK03287, truB, tRNA pseudouridine synthase B; Provisional.	1.05955e-124
NC_013172.1|WP_012804647.1|1149705_1150299_+|AAA-family-ATPase	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	8.86465e-07
NC_013172.1|WP_164929901.1|1165260_1167516_+|polyribonucleotide-nucleotidyltransferase	gnl|CDD|131743	TIGR02696, polyribonucleotide_nucleotidyltransferase, guanosine pentaphosphate synthetase I/polynucleotide phosphorylase. Sohlberg, et al. present characterization of two proteins from Streptomyces coelicolor. The protein in this family was shown to have poly(A) polymerase activity and may be responsible for polyadenylating RNA in this species. Reference 2 showed that a nearly identical plasmid-encoded protein from Streptomyces antibioticus is a bifunctional enzyme that acts also as a guanosine pentaphosphate synthetase.	0
NC_013172.1|WP_012804661.1|1167679_1169020_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	7.61235e-98
NC_013172.1|WP_012804646.1|1148788_1149625_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.93489e-17
NC_013172.1|WP_165446567.1|1150310_1151636_-|hypothetical-protein	gnl|CDD|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	1.76571e-22
NC_013172.1|WP_012804662.1|1169159_1169930_+|4-hydroxy-tetrahydrodipicolinate-reductase	gnl|CDD|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	5.15738e-90
NC_013172.1|WP_012804652.1|1155521_1156508_+|transcription-termination/antitermination-protein-NusA	gnl|CDD|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	3.6343e-178
NC_013172.1|WP_012804644.1|1146726_1147887_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl|CDD|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
NC_013172.1|WP_012804651.1|1154857_1155520_+|ribosome-maturation-factor	gnl|CDD|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	5.32745e-30
NC_013172.1|WP_012804655.1|1160149_1160659_+|30S-ribosome-binding-factor-RbfA	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	1.49947e-49
NC_013172.1|WP_012804649.1|1151848_1153633_+|proline--tRNA-ligase	gnl|CDD|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NC_013172.1|WP_012804664.1|1170392_1170707_-|AzlD-domain-containing-protein	gnl|CDD|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	0.00295605
NC_013172.1|WP_012804658.1|1163616_1164633_+|bifunctional-riboflavin-kinase/FAD-synthetase	gnl|CDD|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	2.14912e-100

Protein sequences

>NC_013172.1|WP_012804653.1|1156648_1156954_+|YlxR-family-protein
MVTRSSAHRPERTCVGCRQVAPRDQLVRLVRESAPGGSAPRVRVDPSGSAPGRGAWLHPDTSCLELALRRGGFPRSFRGPVDTGPLAQTLEDPDFTRTWNR
>NC_013172.1|WP_012804652.1|1155521_1156508_+|transcription-termination/antitermination-protein-NusA
MDIDMGALRALERERDIRLPVLLDAIRSALHAAYLHTDHPVRDSEVLIDESTGEVAVIARERDADGVVVEEWDDTPENFGRVAASTARQVIFQRIRDLEDEAVLGEYADRADDIVSGIIQQGRDPRMVLVDLGEVEAVLPPHERVPGEDYSHGRRLRAYVTEARRGPKGPQITLSRSHPNLVRRLFDLEVPEVADGTVEITGLAREAGHRTKMSVRATVPGVNAKGSCIGPMGARVRSVMNELGGEKIDIVDFDEDPATYVANALSPSKVSSVTVIDEVGRAVRAVVPETQLSLAIGKDGQNARLAAKLTGWKIDIRPDSAPDPAPAD
>NC_013172.1|WP_012804651.1|1154857_1155520_+|ribosome-maturation-factor
MSALEDQTILRETATEVLASHGLVLEEVEIRRGGGTPQVRLIVDLPEDQLGSADLDTVAEASRALSEAVDADDAVLGSAPVLLEVTTPGVDRELTAPRHFRRARGRLLSLTTEEGTTLRARLLAVDGEELALRQEPGRDDRGRPLKLPAGTTERLRLPLAEVARARVEVEFDPPADLEELLAEITGADAAPASRAATDPGPGDSPGPTAATDHPAATKES
>NC_013172.1|WP_164930168.1|1153646_1154822_-|DUF4439-domain-containing-protein
MLRGDPRSGPPRIVGAPGPCLHQGPRCENPPVIPPARPSRTAVPVTRRALLGAAGALAVLPLASCGPIALGRPEQYTPPPPGIDDLYRVDLLAVLDRAAAGTQALVALAGPDEDPALSGALSELAGALPVQRTALLTGAEYEKELEAAEEPAAEQTSPPPPEAPEDLPALLECLVELRDLAAAAARQVSGSLARPLSGIAAHTAWSALRLHRAAGEAVSEGVPASPTAEEIVPQREVPASDPPSIGAESDYHSTLERAQLEEWYAGYLGEVLASRTEGDARERHLDLTERHRERAEELGRIAEEDGAPVVARQAVYALPGDMHDAELVETLPRLLAQGLLLDHIALVGAAPFERRSLPIAAALQEAEQLAALADRMEPLPGLEVEQAPTAG
>NC_013172.1|WP_012804649.1|1151848_1153633_+|proline--tRNA-ligase
MIRLSSSFIRTLREDPADAEVASHKLLVRAGYIRRSAAGVYTWLPLGLKVLRKVEQIVREEQDAIGGQEVLFSALQPREPYEATGRWEDYGPNLFRLQDRKQDDYLLAPTHEEMFTLTVKDLFSSYKDLPTMLYQIQAKYRDEARPRAGLLRTREFLMKDAYSFDVDDEGLDASYEKQRLAYQRTFERLGLPTVICRADAGAMGGSRSEEFLHPTPVGEDTFVVSDGGYAANVEAVTTPAPPALDEAAIAALPAMHVEDTPGASTIAKLTDFSNQAFPGKGPTTDSGEWTRYEMLKHLVYLLTHPDGSTEPLVIALPGDREVDAKRLEAAVAPAIASPFTDEDFSAHPVLKKGYIGPEGLGLEAEAGICYLVDPRVVPGSSWVAGAGEKDKHVYDLVYGRDFTADGTIEAAEVRDGDPAPDGSGPMRLTRGMEMGHIFQLGRTYAEALGLKVLDENGKSVVVTMGSYGIGVTRAIAAVAELCHDEKGLCWPRQLAPADVHIVATGKDPAIFAEAERIAGALEARGLEVLYDDRPKVSPGVKFKDSELLGVPTSVVVGRGLATGVVEVRDRAGGEIREVSPEEVVDAVTAEVRGA
>NC_013172.1|WP_165446567.1|1150310_1151636_-|hypothetical-protein
MLGGAGALGAVVGLGALGAVGAGTGTGTRPGRRATDPRSVIPLWSATVAYDSAEQRALVGGRSPQLPLDPGTRFGSELAPSSPARARAEEFLQGTAEWQGMLRESLGDLPALLDLAGSALWDLWVLTDELPAPVAGWSSSWRYMWPRDAAFCAAALARIGHRDTALSVLEHLGSLQARDGWFEARYDPATGRAPDRRPRQFDGAGLLLWAASEAVPPEGEEGRDRALERLAPLITRSLGTLHRCTSGGTGLPPVSPDYWEVHEESVTLGTMAATLTGLQAGARVAPTSAARRTAQQAARSFTALCEGTFGTTGFQRYRSGGGADSALALLDATGVHDVAAPAQLLSLREELARPGGGIAPGASWREDGVSWTPSTSLLGLALARAGERTAALEILTWLAEHRTEAGSLPEKVLFDGRPAEVAPLAWTAANVLLSLDVLARG
>NC_013172.1|WP_012804647.1|1149705_1150299_+|AAA-family-ATPase
MNRSTVSAAAEGGEQSGARLYLLQGAPAVGKLTLARELEARTGAIVVDNHLVNNAVFVPLGMGRDAEVTLEQTDALRARVLDVVLEATLAAPAALSHVFTNWLPDDPANAAHVERLRELARRRGARFVPVWMSASAEALTARVASPGRAERSKLVDPAVLRELLTRPELPPPADALTLELSETTPAQAAQQLLAALA
>NC_013172.1|WP_012804646.1|1148788_1149625_-|class-I-SAM-dependent-methyltransferase
MSTAQSWFEDNRANWDDRAALHEAAGYGIEELVEDPARITPEVAQERERLGDLAGLDVAHLQCHLGTDTVSLSRLGARRVVGVDLSPGSLRRARTIAERAGAAIEFVEANVYDAREAVEGSFDLVYTSLGVLCWLPDVTAWARVIASLLRPGGRFMIRDDHPMFMTVGEDVSEALRIEQPYFQRRDPMTWDEPGSYVEAPADAPEFAHGVNHQWNHSIGEILTAVLEAGLVLDSFEETPFSAWCPWPELMVREGERFRLREDPDRLALQFVLTAHRPG
>NC_013172.1|WP_012804645.1|1147893_1148769_+|GNAT-family-N-acetyltransferase
MFRRGGRVRAIRSGGYDAALALALTDPVVNALAGARLREVARTGALPQEFSLAGDEQHPEGLLWHGVNLAPLSATPRALEDFGRHQASRARRSSSVVGDRRAVETLWHDLAEPWGAGVREYRWSQPLLLAEEPPAPQRIAPGGATVGGEAGLRPAVPGEEEAVFPAAVAMFREEVGIDPLAGDGGRSYRARVADLIRRRRTYVVIEEGEVRFKADVGALFGPVAQIHGVWVRPAHRGRGLGRAGMAELVRQVRRDHAPQVSLYVNDYNEPARRAYAAAGFRQVGELTTILF
>NC_013172.1|WP_012804644.1|1146726_1147887_+|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MTSVSLGIPSVKQPPPVLAPRRKTRKVKLGDLYVGGDAPITVQSMTTTPTHDINATLQQIAELTTAGCDIVRVACPRQEDADALVAIAAKSPIPVIADIHFQPKYVFAAIEAGCAGVRVNPGNIRRFDDQVKDIAKAANDHGTALRIGVNAGSIDKRMMTGDRVTPEALVASAKWEASLFEEHGFHDFGISVKHNDPIIMVEAYRQLSEAGDWPLHLGVTEAGPAFQGTIKSSIAFGILLGEGIGDTIRVSLSAPPVEEVKVGNQILQSLNLKPRKLDIVSCPSCGRAQVDVYTLADKVTEGLKHLEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPEEDIVETLLAEANRIAAEMGEDASAGSAPSVSVG
>NC_013172.1|WP_012804655.1|1160149_1160659_+|30S-ribosome-binding-factor-RbfA
MNDNPRALRLADRIKVIVATMLDTRVKDPRLGFVTITDVRVTGDLQHATVFYTVFGTDEEREGTAAALESATGMLRREVGRQTGVRLTPTLEFIADAVPENARVIEDLLSEARGRDAELEKAKAGATYAGEADPYRKPREEELEDEDSTGATEPGDDTSGEDETGREQP
>NC_013172.1|WP_164930169.1|1160712_1161612_+|tRNA-pseudouridine(55)-synthase-TruB
MLLVDKAAGRTSHDVVARVRWLLGTKKVGHAGTLDPMATGLLVLGVGQGTRLLTYLVGLDKTYEATIRLGRSTTTDDREGEPLGEIVDASGLTAAEISPHLASLRGDIAQVPSTVSAIKIDGKRAYARARAGEDVQLAARPVTVSRFEAGEARTEGEFLDLDAVIDCSSGTYVRALARDLGAALGMGGHLTALRRTAVGPFSVQDALRVPARGEGDDVDLPLQGLGAVAARVLPVLEVDAAQAAALGTGQRLRSDAAGDCDEADGPVAALDAAGRLIAILEREGAGWRPVLVVPVDARC
>NC_013172.1|WP_012804657.1|1161746_1163270_-|L,D-transpeptidase
MTNVTDTAAPGGPLRPTGRHGRRRVALVLVAVFAVLAVLLTGGALAYAKQFEGRALPGTTLLGQDIAGQTPEEISSLVVERGSEVTVTVTAGDQTLEAGLEDLGVTVDAAATAQAAVDRDDSFTGVLSSTWAGEHEVAPVVSVDEEKAAEFAKGLVPEDRTDPVDAQVSFDEEEQAWTAEPGRNGQGVDPQPLVDAVTQNAPALEDFSVEQPLEEIAPQITTEEAEEVVGTISTLLEQPMSITGADGETHEVSAERRNGWISVEAEEDGQSLGISVDEDAVREWVSARADKDAVEAEDGIEQVDEDGEVVKVVTEKKDGLKITNTDAVADELIAALSGTTPLEAAFESEKVTAEVEKVDAPKDEDEDGEDDSSDTPANPTGEKWIDVDLSAKTVTAYVGDTPVWGPRTMVDGKAGNETVTGTYEIYLRYDRQDMTNAGYYEEDDPEYYYTPDVPWVQYFHRGYAFHGAPWRSSFGYSGSHGCINLPVSDAKWLYDWASIGTKTVVHN
>NC_013172.1|WP_012804658.1|1163616_1164633_+|bifunctional-riboflavin-kinase/FAD-synthetase
MTRVPIWHSVDEVPAELGPTAVSIGNYDGVHRGHRFVLDQLRRHAQARSLAPVALTFWPHPRHVMGDPARTPLLTGHEDRDRLLLLAGMHGVLDLEFTHDFAQYSPEDFVRVFLVEGLGVKCVVLGEDALFGRGNSGDIGTMRELGRAFGFDVVTVDELGPEGTGTGRISSSGIRSALLEGEVETANEALGRLHTVTDVVHHGFRRGHELGFPTANLGPSPAGLIPADGVYAGYLTVTEQAPSHLGVEPLAGAPATISIGTNPTFEADGAPRRTVEAYVHGDHDLDLYGDVVRLEFVAFQRPTLKFDSVDSLIEQMDRDVEVTRRTLAAERSRPGIAG
>NC_013172.1|WP_012804659.1|1164778_1165048_+|30S-ribosomal-protein-S15
MAFDTATKQQIIKEYGTTEGDTGSPEVQIALLSHRITYLTEHLKTHKHDHHTRRGLMLLVGQRKRLLQYLQSADIERYRSLIKRLGIRR
>NC_013172.1|WP_164929901.1|1165260_1167516_+|polyribonucleotide-nucleotidyltransferase
MEGPEITATTAVIDNGSYGRREIRFETGRLAQQAAGAVAVYLDDDTMVFSATAVSNKPKEHFDFFPLTIDVEERMYAAGRIPGSFFRREGRPGTDAILAARLTDRPLRPAFVKGLRNEVQVVLTVMANGPDDAYDVVGINGASASTQISGLPFSGPIGAVRIALMPNSQGGGQWVAFPTFSQLDEAVFSMVVAGRIVEDDVAIMMVEAEATDNSWNLIKEQGAIAPTESVVAEGIEAAKVFIRSLCVAQQELAATAAKPVREFPLFLDYQDDAYEIVEAAATERLAEVMSIAAKTEREERTEQLLAEITEELSGEGKQLEDREKEVTGAFRALTKQVVRKKVLTEGVRIDGRGLRDIRALSAEVEVLPRVHGSALFQRGETQIMGVSTLNMLKMEQQIDSLGPVERKRYIHHYNFPPYSTGETGRVGSPKRREVGHGMLAERAIVPVLPSREEFPYAIRQVSEALGSNGSTSMGSVCASTLSLLNAGVPLRAPVAGIAMGLISDTIEGEIRYAALTDILGAEDAFGDMDFKVAGTGEFITAIQLDTKLDGLPASVLTGALSQAHEARLAILGVLGEAIDAPDEMSPNAPRVLAVTVPVDKIGAVIGPKGQMINQIQDDTGADITIEDDGTVYIGATDGPSAEAARSAVNAIANPMVPEVGERYLGTVVRVVDFGAFISLTPGKDGLLHVTQLRKLNGGKRVDNVEDVATVGQKIEVEIREIDARGKISLAVIEEDEAESAESAASEATTAE
>NC_013172.1|WP_012804661.1|1167679_1169020_+|insulinase-family-protein
MPLDLSYDDPASDVLLDAATGVRRSILPGGVRLLTQTDRSVRSATIGLWLPVGSRDETPAHAGSTHVLEHLLFKGTPRRSAMDIATAFDEVGGDSNALTAKEHTLYYGRVRSSDIPMAVDVLTDMITASLLEQDALATEREVILEELAMAEDDPGDIGYETFLADVLGPDTAIGRPVGGTAASVEALTIEDVRAHFTEHYRPDNLVVTAVGDLDHDELAGLLQDGLRRGGWELEPGRLPSRRQRPAHPDASGAAAGSAADVAALAPHRLGRPTEQNHIYLGGRGLTALSEDRHALSVLMSVLGGGMSSRLFQNIREQRGLAYSVYSFSAGYRDAGLFGMYAACRPGRTTQVVELLAEELARMGERGIDELELARAKGQITGSFALGLEDTSSRMGRLGTIELVHGRYTSVDETLERIAAVGAGDVRALAARLADSFSTRVEVGPES
>NC_013172.1|WP_012804662.1|1169159_1169930_+|4-hydroxy-tetrahydrodipicolinate-reductase
MTPNAPSRPTRVAVLGASGRMGAAACRAVEEAPDLELVARIGRGDELSAITEAGAEVAIDLTIPSVTAENVRWLVEHGIHAVVGTTGWTEESLEALRTQLEGAEGVGVLIAPNFAIGAVLAMRFAEIAARYYDSAEIIEMHHENKLDAPSGTARHTAAAIARGRAEAGLGPVPDATEKDPDGARGAVVDGIHVHAVRQRGLVAHEVVQFGGVGEQFVLRHDSFDRISFMPGVLLGVREVAAHPGLTVGLDGYMDLG
>NC_013172.1|WP_012804663.1|1169960_1170362_+|hypothetical-protein
MKQKLFVAVLVLITAAYAWGLGWIAWGFVRAGSALGYGMALGIVILLALTIWVTWREMLFGLASARLAAQYEPPVEADGEDQRAEFEASRAALQEGAEHDWRAWFRLALAYDALRDRKGARMATRRAIAEHRG
>NC_013172.1|WP_012804664.1|1170392_1170707_-|AzlD-domain-containing-protein
MSLLWVAVIAASVLSFAQKWIGYQAPPDVLERPRVSRVTTLLPIALLGALVATQAATSGSEIVLDARLAALAAAAGLLWARAPFLVVVIGAAVVAAGLRALGWS

Crispr_ID: NC_013172_5

• CRISPR_ID: NC_013172_5
• CRISPR_location: 1535925-1536319
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NC_013172_5

Consensus_repeat	Method
GACCGGCCTCGCCGTGACGACCG	CRISPRCasFinder

spacers of NC_013172_5

>5.1|1535948|31|NC_013172|CRISPRCasFinder
TGGTCGCGGCGAGAGCAGAGGGCCCCGCGAG
>5.2|1536002|43|NC_013172|CRISPRCasFinder
TCCATGGGAGAAGCGCGATCGGAAGGACGTCCGGCCGCGCGAG
>5.3|1536068|49|NC_013172|CRISPRCasFinder
TCCGCGGCGCGATGACCGGCCCCGCCGCGACGATCGCCCGTACTCCTCC
>5.4|1536140|49|NC_013172|CRISPRCasFinder
CCCCCGTCGGGATGATCGCCCGCGCCGGGATGACCGGCCGTGGACCCCG
>5.5|1536212|31|NC_013172|CRISPRCasFinder
GCCGCGCCGGGAGGACCGCCCGCGCCGGGAA
>5.6|1536266|31|NC_013172|CRISPRCasFinder
CCCGTACGCGTCTGACCGGCCTCGCCGGGAT

CRISPR arrays and Neighbor proteins around NC_013172_5

CRISPR arrays

The CRISPR arrays of NC_013172_5

>merge|NC_013172|5|1535925-1536319|CRISPRCasFinder
GACCGTCGGCGTGATGACGACCGTGGTCGCGGCGAGAGCAGAGGGCCCCGCGAGGATCGCGGGCGCCGCGAGGACCGTCCATGGGAGAAGCGCGATCGGAAGGACGTCCGGCCGCGCGAGGACCGTCCGGGCCGCGAGGACCGTCCGCGGCGCGATGACCGGCCCCGCCGCGACGATCGCCCGTACTCCTCCGACCGGCCTCGCCGTGACGACCGCCCCCGTCGGGATGATCGCCCGCGCCGGGATGACCGGCCGTGGACCCCGGACCGCCCTCGCCGTGACGACCGGCCGCGCCGGGAGGACCGCCCGCGCCGGGAAGACCGGCAGCGGCGCGATGATCGCCCGTACGCGTCTGACCGGCCTCGCCGGGATGCCCGTCCCCGTCGGGATGACCG

>NC_013172|5|5|1535925-1536319|CRISPRCasFinder
GACCGTCGGCGTGATGACGACCG	TGGTCGCGGCGAGAGCAGAGGGCCCCGCGAG
GATCGCGGGCGCCGCGAGGACCG	TCCATGGGAGAAGCGCGATCGGAAGGACGTCCGGCCGCGCGAG
GACCGTCCGGGCCGCGAGGACCG	TCCGCGGCGCGATGACCGGCCCCGCCGCGACGATCGCCCGTACTCCTCC
GACCGGCCTCGCCGTGACGACCG	CCCCCGTCGGGATGATCGCCCGCGCCGGGATGACCGGCCGTGGACCCCG
GACCGCCCTCGCCGTGACGACCG	GCCGCGCCGGGAGGACCGCCCGCGCCGGGAA
GACCGGCAGCGGCGCGATGATCG	CCCGTACGCGTCTGACCGGCCTCGCCGGGAT
GCCCGTCCCCGTCGGGATGACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_013172.1|WP_012804962.1|1517733_1519242_+|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NC_013172.1|WP_012804964.1|1519852_1521016_-|phosphoserine-transaminase	unknown	unknown	gnl|CDD|235103
NC_013172.1|WP_164930195.1|1519271_1519730_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_013172.1|WP_012804979.1|1545166_1546933_+|membrane-protein	unknown	unknown	gnl|CDD|240528
NC_013172.1|WP_012804970.1|1534215_1535217_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_013172.1|WP_165446568.1|1548092_1549871_+|CTP-synthase	unknown	unknown	gnl|CDD|235437
NC_013172.1|WP_012804974.1|1539293_1540238_+|NAD-kinase	unknown	unknown	gnl|CDD|235121
NC_013172.1|WP_012804968.1|1532185_1533184_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|226666
NC_013172.1|WP_012804973.1|1538442_1539288_+|TlyA-family-RNA-methyltransferase	unknown	unknown	gnl|CDD|224110
NC_013172.1|WP_012804961.1|1516884_1517682_+|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl|CDD|238693
NC_013172.1|WP_012804967.1|1530482_1532141_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270298
NC_013172.1|WP_012804977.1|1543206_1544364_+|copper-transporter	unknown	unknown	gnl|CDD|378653
NC_013172.1|WP_012804980.1|1546929_1547985_+|glycosyltransferase	unknown	unknown	gnl|CDD|340837
NC_013172.1|WP_012804969.1|1533180_1534170_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_013172.1|WP_012804978.1|1544360_1545170_+|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_012804972.1|1537414_1538446_+|HAD-IIA-family-hydrolase	unknown	unknown	gnl|CDD|319832
NC_013172.1|WP_012804975.1|1540252_1542025_+|DNA-repair-protein-RecN	unknown	unknown	gnl|CDD|223571
NC_013172.1|WP_012804966.1|1527708_1530264_-|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl|CDD|224389
NC_013172.1|WP_012804965.1|1521145_1521844_+|demethylmenaquinone-methyltransferase	unknown	unknown	gnl|CDD|234689
NC_013172.1|WP_012804976.1|1542021_1543191_+|hypothetical-protein	unknown	unknown	gnl|CDD|227162

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_013172.1|WP_012804962.1|1517733_1519242_+|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.02146e-116
NC_013172.1|WP_012804964.1|1519852_1521016_-|phosphoserine-transaminase	gnl|CDD|235103	PRK03080, PRK03080, phosphoserine transaminase.	9.69537e-177
NC_013172.1|WP_164930195.1|1519271_1519730_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.2762e-20
NC_013172.1|WP_012804970.1|1534215_1535217_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.01135e-58
NC_013172.1|WP_165446568.1|1548092_1549871_+|CTP-synthase	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_013172.1|WP_012804974.1|1539293_1540238_+|NAD-kinase	gnl|CDD|235121	PRK03372, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	1.22818e-128
NC_013172.1|WP_012804968.1|1532185_1533184_+|sugar-ABC-transporter-permease	gnl|CDD|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	1.0484e-108
NC_013172.1|WP_012804973.1|1538442_1539288_+|TlyA-family-RNA-methyltransferase	gnl|CDD|224110	COG1189, COG1189, Predicted rRNA methylase [Translation, ribosomal structure and biogenesis].	6.28053e-87
NC_013172.1|WP_012804961.1|1516884_1517682_+|glucosamine-6-phosphate-deaminase	gnl|CDD|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	1.92133e-124
NC_013172.1|WP_012804967.1|1530482_1532141_+|extracellular-solute-binding-protein	gnl|CDD|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	8.64161e-42
NC_013172.1|WP_012804977.1|1543206_1544364_+|copper-transporter	gnl|CDD|378653	pfam11382, MctB, Copper transport outer membrane protein, MctB. Outer membrane channel protein MctB in Mycobacterium tuberculosis is part of a Cu resistance mechanism that ensures low intracellular Cu levels in the bacterium. Human resisitance to bacteria, mediated via IFN-gamma-mediated activation of macrophages, may involve the use of reactive Cu(1) in the presence of hyrodgen peroxide, since acitivated Cu is toxic to bacteria. IFN-gamma stimulates the trafficking of the Cu transporter ATP7a to the vesicles that fuse with phagosomes and these phagosomes are found to have a high Cu content and an increaseed bactericidal activity against E.coli. Using MctB, Mycobacterium tuberculosis may limit the amount of excess Cu within it whole in the host.	1.18527e-57
NC_013172.1|WP_012804980.1|1546929_1547985_+|glycosyltransferase	gnl|CDD|340837	cd03808, GT4_CapM-like, capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.	7.41631e-41
NC_013172.1|WP_012804969.1|1533180_1534170_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.48932e-70
NC_013172.1|WP_012804979.1|1545166_1546933_+|membrane-protein	gnl|CDD|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.6272e-43
NC_013172.1|WP_012804972.1|1537414_1538446_+|HAD-IIA-family-hydrolase	gnl|CDD|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.53591e-97
NC_013172.1|WP_012804975.1|1540252_1542025_+|DNA-repair-protein-RecN	gnl|CDD|223571	COG0497, RecN, ATPase involved in DNA repair [DNA replication, recombination, and repair].	2.66083e-154
NC_013172.1|WP_012804966.1|1527708_1530264_-|glycoside-hydrolase-family-3-protein	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	1.78965e-37
NC_013172.1|WP_012804965.1|1521145_1521844_+|demethylmenaquinone-methyltransferase	gnl|CDD|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	5.36339e-103
NC_013172.1|WP_012804976.1|1542021_1543191_+|hypothetical-protein	gnl|CDD|227162	COG4825, COG4825, Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown].	1.87066e-115

Protein sequences

>NC_013172.1|WP_012804970.1|1534215_1535217_-|LacI-family-DNA-binding-transcriptional-regulator
MATMSDIAREAGVSLSTVSYALSGKRTISESTRERINAAITRLSYHPHAGARALASQRAGAIGLAVPLAEDVDAHVVMMFVRSLMRAAHDASSEILLIAGEDHEATERVLAEGRVDALVVMDVVEDDPRIPVLAEATRPVVLLGYPSDARGIPRVDFDFEEASILAVTELHRRGARRLVMIGSPAATQSRHATYADRATRGFRTACSRLGLSARHVVHDHEVDPTRELIHSVLAQDRPDALIIHNESALPAIHRALTAEGVEMPGDLQVVAIAPRETTLLGAVEYTAVQIPVEEIGQTAVAVATDLIEGRDGPRDQLIAPALIARDTTHPVHG
>NC_013172.1|WP_012804969.1|1533180_1534170_+|carbohydrate-ABC-transporter-permease
MSVSTGTEPDPRGAPVRQGVATAAVSDIRRTPRRRRSSRPVWDEAPSIPAQGAKGVVLVMICLAVLVPLYTIILTSLSPQAAITRAGGLVLVPDGLTLDAYRQVLSGGIVTRAVLVSLGVTGVGTAISLVVSVLAAYGLSRPGSLLHTPILFLMLGTMFFGAGMIPMYLLVSGLGLIDSYWALILPTAVSAFNIVIMRGFFQGIDQGILESARIDGASDWRILFQMVLPMSKAVVAVVALFYAVGYWNAFFNAILYINDSAKQPLQVVLRSFVLQGVSVPGQVDVGSGQVATLAVQMAVMVIALVPVVLVYPFIQRHFKSGVMIGAVKG
>NC_013172.1|WP_012804968.1|1532185_1533184_+|sugar-ABC-transporter-permease
MSTDTAPPVRAARPARARGKRGASRPAPRRVSLASRLRRDRTLILMALPMVVLLLIFAYIPILGNVIAFQDYSPFIGIRDSPWLGMQQFERVIADPLFWNAVKNTLVITAFQLVFYFPIPIALAILLNSVLSEKVRTVIQSIVYLPHFFSWVVVVSVFHQILGGAGLLSQFTREFGLGSMNVMTNPDTFLFLITSQVVWKDAGWGIIVFLAALNAIDPALYESAAMDGAGKWRRIWHITLPGMRAVIVLLLILNLGNALTVGFEQLILQRDAVGAGRAEVLDTFVYYTGVQNGDWSYAAAAGLLKGVVSMILVLGANKVAHLFGEAGVYQKA
>NC_013172.1|WP_012804967.1|1530482_1532141_+|extracellular-solute-binding-protein
MNSPLHTNAVSRRRLLGYLGLGAGTLGLAACGGSGGAGGTAAGSGGVLTGAELAAEVEASVPNSSLEFLVEPDFPSVNGSTPGYVTMPDPLVDGVSEVPGSGGSYTVMSPAWWTSPPGLGDNAYYEAVNEELGATLEFQVADGNSYADKVQTVLASPKNVPDWMVIPSWNIPPRFVEGVGNVFQDLTDHLAGEGILDYPNLARLDPAAWEYSMFNGRIYGLPYPSELVTDAVFYRRDLFEELGVEPPTDAESFLEVLSEITDPGANRWGCENLWNTAQLMYALPPTFAERDGELVHRFEMEEFKEAIIWLTKVIESGAMHPDAVAGNDGAAKDRFESGQTLVMNDGVGGWHEALARVRPSNPDFDQMAMDLFAPDGGAPTLYRGAPVNIFSFLKKTDDEDQVREMLRIADWCASQFGTKEFDLLTYGIEGTHFERDEHGIPQLNDQGRSEVTSTYQFLAQPAIVNAKVQFPDYVEASSEWMARQSEHVVDPLFYGIQIQEPAEFGSLGQPLDDLVVDISRGRKDISELDAAVENWRTSGGDKLREFYGEFMA
>NC_013172.1|WP_012804966.1|1527708_1530264_-|glycoside-hydrolase-family-3-protein
MAHPVPPMWLEARPELGATDSAHLEHARSLVRAMTLEEKLPFLHQHSPGLERLGIGPFSTGTEALHGVAWRGPAVTYPQPVGLAATWDEDLLAAVGDQIAREVREHHAQEDPASLNVWSPVVNPLRHPLWGRTEEGLSEDPLLNARLGTAIARGLRGEGPCWTTVPTLKHFLGYSHEVDRAATSSSLPPRVLHEYELPGYEEALASGAAGAVMLSYNLVDGVPAHLSPLVNDHLRRVVADPDLLFVVSDAGAPTNLVQIQDAAADLTEAVAAMLRAGVDSFTDHGRDSGPTLRAAREALARGLVQEQHIDHAVVRQLVARARTGEFGAAADASGHTATGTSNSPTGAGFDRARAVELSQEVAARAAVLLRHQDEALPARPGSTLAVIGHLGGTVLQDWYSGELMDPVSLREALEDSHDGPVRFAAGLDIVQLSADGVPVLCGAQERLELAAASFKDDVGAVDDEHPGLGEPSHAAEGSDAGGARFEVRDHGHGVLSLRETSTGLWLAPDAHGHLRARAPRIGGWVVQETFRPLRSADGRVRLQHVGSGRWLRAERQTGRLVLGGTEAAQALELSWQVRVSGLQQAREAMDGADLAILVAGNEPHVHGRETEDRASLSLAGPDQSLVDLLAEAAPTTKTALVLFSSYPYDLGRHEEAAQAVVWSSHAGARQGPALASLLRGEREFSGRLAQAWIRERALTDILDYDVISSAATYLYGQEALYPFGHGLALEPTRWSDVALEASGQSVSVAVTLERDGAWPAHEVVQVYATVDAAAYPHDLGPLPALRLIGSRVVEVPASGGVRARLEIPWTRLRVWSEEAADFVAPTGTVTLHVARSSDDVERSAEVSVPVL
>NC_013172.1|WP_012804965.1|1521145_1521844_+|demethylmenaquinone-methyltransferase
MSRADLEKQPYDVATMFDGIAQRYDLMNDIAAMGQVGMWRDLMVQALEIAPGDEVLDLAAGTGTSTTAIARAGARVAAADFSLGMMSEGRRRGAPVPFIGADAQRLPFAEDSFDAAVISFGLRNVHEPRRALAEMVRVVRPGGRVVVCEFSTPSWRPFRTVYEKYLLRALPAVAGMVTTTADAYEYLAESILEWPDQEALRGWFLAAGMERAQYRNLSGGIVALHRGVVPVS
>NC_013172.1|WP_012804964.1|1519852_1521016_-|phosphoserine-transaminase
MTAASSARTDALRALSIPQHLLPADGRFGSGPSRIRAEQVETLQSVSRTVLGTSHRQAPVKQLVSRVRSGLAALFQLPEGYEVVLGNGGSTAFWDLAVFSLIERRSQHLVLGEFSQKFATESAGAPHLAEPEVLRSAPGSFPQAVASAEVDAYAWPHNETSTGVMVPVRRPAGATQDQLVLVDATSVAGAAAVDISQTDAYYFAPQKAFASDGGLWLSVLSPAAIERAQRLAQDGSRWIPSFLSLTSAIDNSRKEQTLNTPAVATLVLLAEQIEWILDQGGLAWADARTRTTSGMLQSWAASREEITPFVEDPAARSQVVTTLDVDESIDATAITSVLREHGVVDIEPYRKLGRNQLRIATFPAVGEEDVAALIAVLDHVLDATAGA
>NC_013172.1|WP_164930195.1|1519271_1519730_+|MarR-family-transcriptional-regulator
MPAGEESAGGGENVELAAGLQRVLLVSSRILRSHTASEEVSAPQFSVLAYLQRTGESTPGALAEFDHVSPPVMTRILGRLEHAGLVRRDAHPGDGRQVRVTLTDRGQQLVLAGRERRHAWLRSRIEEATPAQQAALRDASRVLQEILIPPRD
>NC_013172.1|WP_012804962.1|1517733_1519242_+|NCS2-family-permease
MQQADPSSLPSPAAPPAARAPRSGLDRYFRISERGSTVGREIRGGLVTFFSMCYIVVLNPLIIGTVPDSTGMYLGGGTEPNLPAVAAGTALIAGLLSVVMGAWAKFPLALAAGLGLNAYLAYSVVPLPGMTWGGAMGMVLLEGVVILALVLTGFRRAVFSAVPPFLKTAIAVGIGLFIAFLGLFNAKFVTTAADTPVQLGNDGSLIGWPTAVFVVGLLLMFVLWIRKVPGAILIAIVTATVLSLIVERVLHLGAFSAADGTDPGNPGGWAMNVPAMTEFPVRMPDFATLFTVDPLGGITAAGVIGATVIVFSLLLADFFDTMGTMVGVASGAGLVDEAGDIPHSQRILVVDSAAAIAGGIGGVSSNTSFVESTSGVAEGARTGLAAIVVGVLFLLSTFLSPLVAMVPYEAATPALVMVGFLMMTQITDIDFSDVEVAVPSFLTIILMPFAYSITVGMGAGFVMYVLIRVVRGKAREVHWLMYLIAVLFVAYFLRGAIEGLLL
>NC_013172.1|WP_012804961.1|1516884_1517682_+|glucosamine-6-phosphate-deaminase
MEIHIVADAEAGAKVVADVFTRTLQAAGDTGAVLGLATGSSPVPAYEELIRRHREDGLSFARSRAFLLDEYVGLPAGHEQSYHRFIRENFTSHVDIDDAAVVSPDGTAVDPVAEAASYDRRLQEAGGVDLQILGIGSNGHIAFNEPGSSLASRTRVVGLARSTIEDNSRYFASAEDVPVRALSQGLGTILEARRIVLTATGAGKAEAVAQLAEGPISARWPATALQMHPDVTVVVDEAAAARLELADYYRYSRRLEAENPLTSGA
>NC_013172.1|WP_012804972.1|1537414_1538446_+|HAD-IIA-family-hydrolase
MIRRPDPSLLDLYDALLFDLDGTLMHGAQPIPHAAESVEKARAAGRSVVFATNNASRTPQQAAEHLAVVGIPARPEEFVTSPQVASRLLADRLDPGAKVLVVGGPSLAAQVREAGLTPVETDEPDVVAVVQGWSPDLDWSRLAEGAYAIRHGAYWMATNVDATLPTERGLAPGNGSLVAAVRHATGAEPAVAGKPEPGMFEVAAREHRARRPLIIGDRLDTDIEGAVRAGMDSLLVLTGVDGIEAALRAEPVRRPTFILPDLAEIAAPFPLPVVTGDRARCGAVSAAWSDGDITVHGEADDPRVLRAVLALLTSHSADTAWTGRLRDADGAELQVESPPSATR
>NC_013172.1|WP_012804973.1|1538442_1539288_+|TlyA-family-RNA-methyltransferase
MSGDRLDVALLAAGLARSRSHARRIIEEGRARADGRAVTKPSTPIPPGTGLAVVDVPDGVEFASRAAHKLAGALDALGLDPAGLLCLDAGASTGGFSDVLLRRGAAAVIAVDIGHDQLAEHVRSDPRVTVRDGTSVRDLTPELLGTAVDLLVADLSFISLRTVIAALGGVVRPGGELLLMVKPQFEVGRAALPKSGVVTDPAARQEAVRAVAEAAAHAGLRLAAVGPSTLPGQDGNREYFLQLRPHGATSALDAEACDMIVSAVRGDGPRQRRDRHISEEE
>NC_013172.1|WP_012804974.1|1539293_1540238_+|NAD-kinase
MRRFLLYVHTGRRAALRAMLSVLEELRLRNVRAVVVDEQVEEILALPEDMAPPKLITFLTNGAVDVRAAVSAADVVELGIVLGGDGTILRALEAVREADIPVHGVNLGHVGFLAESEVEDLSITVARLLDGDYDIEKRSTLDITVLDSEDELVDHHWALNEASLEKADRQKMINVAIEIDGRPVSSFGADGVLLSTSTGSTAYAFSAGGPVIWPEVDAMMLIPLAAHALFARPLVLGRSSEAAVEMTLDNREDGILTLDGRRGADITAGMRIEARLSPRSVRLARLAPTPFADRLVEKFQLPVVGWRGRGPRTR
>NC_013172.1|WP_012804975.1|1540252_1542025_+|DNA-repair-protein-RecN
MLSTLRIRHIGVIDDAMLDFGPGFTALTGETGAGKTMIVTGLSMLLGGRLDRGRTRGSSTVDGTLSLTGHTELAAALDELGADEDDGEVLVVRRVTRDGRSRAQIGGVPVPIGTLSRLVGTAVTVHGQSDQQRLRDPEAQREALDRFAEAEVGTLLRRHREIWRERSALAARVTELEELLAERDRRGTMLRDALERLEQADPQEDEDVSLRAEIERLGNAEELRGAAGQAALALVGDDDGPAAAPLLAVAAEALGRAARTDPTLEPLVERLDSVRIELSDVAAEISRYAEDIDASPGRMEEANERLHELTVLVRDLGAMLPGPEGPAEEISTLLATSRTAAIDLDRYDGAESERAEAASRLAQLETELDDAAEALTAARTAAASALSAAVQEELHHLEMPDAEIRVDVTAQSHRSHGRDAVAILLAPHPGAQHLPVAQAASGGELSRVMLALEVALSSSRNDRTAAPVFVFDEIDAGIGGRAALAVGQRLARLARHAQVIVVTHLPQVAAHASTHLQIVKSSHDGTTSSTVETLDRPDRIRELARMLAGDDASDVALAHAEELLDEARAVTAEHGTGRAAAHSAGRGAER
>NC_013172.1|WP_012804976.1|1542021_1543191_+|hypothetical-protein
MSPSLAGTARLGKRTKDLTKRLQPGDIAVIDHEDIDRVAAEALVERQPAAVLNVAASTSGRYPNAGPRILVDAGIVLVDGLGPAVFEEVRDGEQLTIAGHEVLLEDRPIAAGTRQDDATVTASLEIAREGLSEQLELFAQNTMEYMLRERDLLLDGIGAPDVATRMDGRPVLIVVRGYHYKEDLATLKPFLRENRPIIIGVDGGADAVLEAGFHPDMIIGDMDSVSDRALRGGSELVVHAYRDGRAPGMERLAALGIEDGAIAFPASGTSEDIAMLLADEKGASVIVAVGTHGTLEEFLDKGRAGMSSTFLTRLRIGSKLVDAKGVSRLYRQRISTFQLVLLALAGLAALAVALWATPGGQALVQILGARLDGVLSWFTMLFSPRVTGA
>NC_013172.1|WP_012804977.1|1543206_1544364_+|copper-transporter
MIDFRYHLVSLISVFLALAVGIVLGAGPLRENLGDQLAGQVEQLRTEQEQLRSDAESLSTKHDQLATFVADLGPELVEGTLEGKQIAVLTDDRSTRPGIERMMSLLTASGVESPTRIGMETSLWSPEGASERAAALEEIRAIAPETLTADPDDELTDAAQLAGLLPTLLHGGGDLSPELRQQLWDVLVDHQLVVVDGTVPAQVDAVIYTGAAPEELAVDTEDEEVATERAQSLLALQTHLLRVLADTGLPAVVSADTPGNDASNGILRTVRGDADFDDLSTTDRLQEADGPLLSVLALIEQVRGGAGAYGTTADAEDRLPSLPETQGVEEQAAAQDQPQDEAQGEAQDAAEGESQDTGQGEAQGQPAGQDAGDGSVTPSDDGGEG
>NC_013172.1|WP_012804978.1|1544360_1545170_+|hypothetical-protein
MSASLRAELRRTNFAGRRVSLLEGALVVGGVTVLATRTGRAADAAVLAGIGALGLIDDVWEPRQRRAGRPVSKGLRGHLGALRSGRLTTGAAKALGIPLLALGGAAAAPGPRRGAMVLADAALVAGSANLANLLDLRPGRALKAVLPGAVVLAAAPGGDPRDESGRRLGLAAALPALLALPADLREHGMLGDAGANILGAAVGGAASRRLPVPARLCLLGGIVALTLTSERVSFSAVIDRSPALRALDQLGRRPAPRPEDTGPAMGEQR
>NC_013172.1|WP_012804979.1|1545166_1546933_+|membrane-protein
MSPADSRPSRAATRRGGIARSVLRGAGVILVVTVFARIAGFVRYLVFGASVGAGDVGTAYTTANMLPNVLFEVVAGGMLAAVVVPLIAGLVPEGDPGGPLEADATADPRTVEQLRSEETSRTAEEGAALADRITSTLLTWTLLGTGVLAVVVIALSGPLAQLLLAAESPGAAGVPLGATLLRIFALQLPLYGIAVVLAAYLQARKRFLWPAMMPLLSSVTVMIAYRAYAHLVPPVATATTIDRAPVWWLGWGTTAGVAIMAVPVVVTAVRSGLRLRPSLSMPPGYGRRALALGGAGLGAVGAQQAVLALVMLLAMRAGGVGTLPVFQYAQALYLLPYAVLVVPLVTSVFPHLSELRLVGDRSGFAKIAAASVRTVMVVSVIGAAMLVAAGPALEHFFHLIDRAGATGVGSTTAGLALGLVGFAVSFQCTRILSAALRARDALLVGSVGWVIAGVVILLVVLPSPERTAAEASTAFGLAMALGMAVAGLVGLARIADVLEHGGHLPLVRRTAIMVPLAVLGGGVPGLLLARRLVTSDAGELRTVLLGALCGLAAGLLAAALMAAADPETTRRMLRRLRAGRHGVARAEG
>NC_013172.1|WP_012804980.1|1546929_1547985_+|glycosyltransferase
MSILLVRPAASGGLAAHVDHELALLRAAGRDVAEAPVRIQERPHSLADLRTLRTLRAAARAATPPVTLHAHGLRAGALAALALIGRRRERLVVTLHNRTVGSRATRTVGALLLRILAGRADAVLAVSPDLAEMARRAGARDVRHAVIPAPGTAPESSAEPAPEPAPDPAPPTAHAAERLEILVIARLAPQKGLHDLLDVADALRRQAPVRIRVAGDGPLHEELAARIRAERLPVELLGRRSDVPALLSAADLLVSTAHWEGQPVSLQEALRSGIAIVATDAGGTRWVTGDAAHLVPVGDVRALAAAITALRESGTRDMAAAASRRRARELPTAQDLLAQLDEVLAADPRGW
>NC_013172.1|WP_165446568.1|1548092_1549871_+|CTP-synthase
MTKHIFVTGGVVSSLGKGLTASSLGMLLRSRGLRVTMQKLDPYLNVDPGTMNPFQHGEVFVTEDGAETDLDIGHYERFLDEDLTAHANVTTGQVYSTVIARERRGEYLGDTVQVIPHITDAIKESMRSQAGDDVDVVITEIGGTVGDIESQPFLEAARQVRQDLGRDSVFFVHVSLVPFIGPSQELKTKPTQHSVAALRSIGIQPDAIVLRSDRELPTSVKAKISSMCDVDLDAVVTCADAPSIYEIPLVLHAEGLDAYAIRRLDLLSRDVDWTQWEELLRRVHEPAYEVTVALVGKYVDLPDAYLSVTEALRAGGFHHRTRVSIRWVESDRCASGEGAAEQLRDVEAIVVPGGFGIRGVDGMVGALHHARRHGIPTLGLCLGMQAMVIEHARHELALATAHSTEFDPATEHPVVATMAEQEGILAGQGDLGGSMRLGSYPHTLVEGSLAARTYGTTEVAERHRHRYEVNNAYRERLEEAGLRLSGTSTLEDGRSLVEFVELDPAVHPFYLGTQAHPEFTSRPTRAHPLFAGLIGAAVERQKSTRLLEVLPEAAGTAPPAASSPVAPSAAASAPAAPAGIEDIMDTGGKEHA

Crispr_ID: NC_013172_6

• CRISPR_ID: NC_013172_6
• CRISPR_location: 2012876-2012977
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_013172_6

Consensus_repeat	Method
TCGGCGGCCGGGGCCTCATCGGCG	CRISPRCasFinder

spacers of NC_013172_6

>6.1|2012900|54|NC_013172|CRISPRCasFinder
ACCGGCTCCTCTGCCGGCTCCTCCGCCGGTTCCTCGGTAGGCTCCTCGGACGCC

CRISPR arrays and Neighbor proteins around NC_013172_6

CRISPR arrays

The CRISPR arrays of NC_013172_6

>merge|NC_013172|6|2012876-2012977|CRISPRCasFinder
TCGGCGGCCGGGGCCTCATCGGCGACCGGCTCCTCTGCCGGCTCCTCCGCCGGTTCCTCGGTAGGCTCCTCGGACGCCTCGGCGGCCGGGGCCTCGTCGGCG

>NC_013172|6|6|2012876-2012977|CRISPRCasFinder
TCGGCGGCCGGGGCCTCATCGGCG	ACCGGCTCCTCTGCCGGCTCCTCCGCCGGTTCCTCGGTAGGCTCCTCGGACGCC
TCGGCGGCCGGGGCCTCGTCGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_013172.1|WP_015775813.1|2002154_2003054_-|Ltp-family-lipoprotein	unknown	unknown	gnl|CDD|377866
NC_013172.1|WP_015775827.1|2019266_2020388_+|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_015775817.1|2005989_2006937_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_013172.1|WP_015775832.1|2025772_2026855_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_013172.1|WP_015775816.1|2005000_2005984_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|226666
NC_013172.1|WP_164930232.1|2015603_2017115_-|polysaccharide-pyruvyl-transferase-family-protein	unknown	unknown	gnl|CDD|377253
NC_013172.1|WP_164929958.1|2010083_2010581_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NC_013172.1|WP_164930230.1|2003995_2004997_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380511
NC_013172.1|WP_015775814.1|2003379_2003766_+|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_015775829.1|2021727_2022945_-|DUF1624-domain-containing-protein	unknown	unknown	gnl|CDD|377915
NC_013172.1|WP_015775834.1|2028691_2029654_-|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_015775818.1|2007010_2008594_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270299
NC_013172.1|WP_015775821.1|2010635_2011250_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|132427
NC_013172.1|WP_015775826.1|2017311_2019207_+|DNA-helicase-RecQ	unknown	unknown	gnl|CDD|273594
NC_013172.1|WP_164930233.1|2020391_2021513_-|metallophosphoesterase	unknown	unknown	gnl|CDD|277329
NC_013172.1|WP_015775830.1|2023036_2024743_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_013172.1|WP_015775831.1|2024739_2025771_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_013172.1|WP_015775824.1|2014027_2015593_+|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NC_013172.1|WP_164930231.1|2011288_2012272_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223669
NC_013172.1|WP_015775819.1|2008647_2010066_+|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl|CDD|350134

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_013172.1|WP_015775813.1|2002154_2003054_-|Ltp-family-lipoprotein	gnl|CDD|377866	pfam07553, Lipoprotein_Ltp, Host cell surface-exposed lipoprotein. This is a family of lipoproteins that is involved in superinfection exclusion. Proteins in this family have been shown to act at the stage of DNA release from the phage head into the cell.	1.93174e-22
NC_013172.1|WP_015775817.1|2005989_2006937_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.06333e-58
NC_013172.1|WP_015775832.1|2025772_2026855_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	8.93779e-107
NC_013172.1|WP_015775816.1|2005000_2005984_+|sugar-ABC-transporter-permease	gnl|CDD|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	4.89087e-132
NC_013172.1|WP_164930232.1|2015603_2017115_-|polysaccharide-pyruvyl-transferase-family-protein	gnl|CDD|377253	pfam04230, PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. CsaB in Bacillus anthracis is necessary for the non-covalent anchoring of proteins containing an SLH (S-layer homology) domain to peptidoglycan-associated pyruvylated polysaccharides. WcaK and AmsJ are involved in the biosynthesis of colanic acid in Escherichia coli and of amylovoran in Erwinia amylovora.	3.7743e-15
NC_013172.1|WP_164929958.1|2010083_2010581_-|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	8.84597e-10
NC_013172.1|WP_164930230.1|2003995_2004997_+|substrate-binding-domain-containing-protein	gnl|CDD|380511	cd06288, PBP1_sucrose_transcription_regulator, ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	2.46121e-112
NC_013172.1|WP_015775829.1|2021727_2022945_-|DUF1624-domain-containing-protein	gnl|CDD|377915	pfam07786, DUF1624, Protein of unknown function (DUF1624). These sequences are found in hypothetical proteins of unknown function expressed by bacterial and archaeal species. The region in question is approximately 230 residues long.	2.15921e-06
NC_013172.1|WP_015775818.1|2007010_2008594_+|extracellular-solute-binding-protein	gnl|CDD|270299	cd13581, PBP2_AlgQ_like_2, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	1.61462e-163
NC_013172.1|WP_015775821.1|2010635_2011250_-|TetR-family-transcriptional-regulator	gnl|CDD|132427	TIGR03384, betaine_BetI, transcriptional repressor BetI. BetI is a DNA-binding transcriptional repressor of the bet (betaine) regulon. In sequence, it is related to TetR (pfam00440). Choline, through BetI, induces the expression of the betaine biosynthesis genes betA and betB by derepression. The choline porter gene betT is also part of this regulon in Escherichia coli. Note that a different transcriptional regulator, ArcA, controls the expression of bet regulon genes in response to oxygen, as BetA is an oxygen-dependent enzyme. [Regulatory functions, DNA interactions].	2.2056e-09
NC_013172.1|WP_015775826.1|2017311_2019207_+|DNA-helicase-RecQ	gnl|CDD|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_013172.1|WP_164930233.1|2020391_2021513_-|metallophosphoesterase	gnl|CDD|277329	cd07383, MPP_Dcr2, Saccharomyces cerevisiae DCR2 phosphatase and related proteins, metallophosphatase domain. DCR2 phosphatase (Dosage-dependent Cell Cycle Regulator 2) functions together with DCR1 (Gid8) in a common pathway to accelerate initiation of DNA replication in Saccharomyces cerevisiae. Genetic analysis suggests that DCR1 functions upstream of DCR2. DCR2 interacts with and dephosphorylates Sic1, an inhibitor of mitotic cyclin/cyclin-dependent kinase complexes, which may serve to trigger the initiation of cell division. DCR2 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	3.28016e-28
NC_013172.1|WP_015775830.1|2023036_2024743_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_013172.1|WP_015775831.1|2024739_2025771_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	9.21159e-73
NC_013172.1|WP_015775824.1|2014027_2015593_+|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	5.48681e-86
NC_013172.1|WP_164930231.1|2011288_2012272_+|alpha/beta-fold-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.70307e-16
NC_013172.1|WP_015775819.1|2008647_2010066_+|glycoside-hydrolase-family-32-protein	gnl|CDD|350134	cd18622, GH32_Inu-like, glycoside hydrolase family 32 protein such as Aspergillus ficuum endo-inulinase (Inu2). This subfamily of glycosyl hydrolase family GH32 includes endo-inulinase (inu2, EC 3.2.1.7), exo-inulinase (Inu1, EC 3.2.1.80), invertase (EC 3.2.1.26), and levan fructotransferase (LftA, EC 4.2.2.16), among others. These enzymes cleave sucrose into fructose and glucose via beta-fructofuranosidase activity, producing invert sugar that is a mixture of dextrorotatory D-glucose and levorotatory D-fructose, thus named invertase (EC 3.2.1.26). These retaining enzymes (i.e. they retain the configuration at anomeric carbon atom of the substrate) catalyze hydrolysis in two steps involving a covalent glycosyl enzyme intermediate: an aspartate located close to the N-terminus acts as the catalytic nucleophile and a glutamate acts as the general acid/base; a conserved aspartate residue in the Arg-Asp-Pro (RDP) motif stabilizes the transition state. These enzymes are predicted to display a 5-fold beta-propeller fold as found for GH43 and CH68. The breakdown of sucrose is widely used as a carbon or energy source by bacteria, fungi, and plants. Invertase is used commercially in the confectionery industry, since fructose has a sweeter taste than sucrose and a lower tendency to crystallize. A common structural feature of all these enzymes is a 5-bladed beta-propeller domain, similar to GH43, that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	6.71601e-141

Protein sequences

>NC_013172.1|WP_164930231.1|2011288_2012272_+|alpha/beta-fold-hydrolase
MRRTDRPLRLRLLLAGLLACALIAGYLVGAGRAAPIGHWRSDEGRTAYLEAYEAAFAEMPDPSEVRDIRTGFGIVRVYRFEGAGPARHPLMVLPGTASGAPVMADNLPSLLEIGDVYAMDLLGEPGRSVQERPLTSDADKAAWLAQVLAALPEEQFHLLGLSIGGWTVTNLALHHPERAASLILLDPVQTFDDIPAGTALRSIPAAFPWMPRSWRDSFSSYTAGGAPVEDVPVARMIEAGMKNYRMVQPAPTRIAPEQIGTLQVPVLAILAGQSVMHDPPTAERTARASLAEGRIEVLPEASHALNGEHPDEIAALTGEFLAEVEER
>NC_013172.1|WP_015775821.1|2010635_2011250_-|TetR-family-transcriptional-regulator
MSTGRRAGRPPGAPQPRREQLIALTIELVGAEGYGAATLGRVAERAELSKASVLHHVGSVSSLLDAAYEQVLSAMVSEVGAAVEAARPTARPRAYITALVGHFRTHPQHTRVAIEALTRRGPSGQSRQRWAPLAQLLAEARAAQGMNAQEETTAQEDLRTAALAVGGAIDAIVAEHHEDPTYDSARAAQQLASAVERTVTARPE
>NC_013172.1|WP_164929958.1|2010083_2010581_-|GNAT-family-N-acetyltransferase
MLADEVRLRPAVPDDAEDAGAMHYASFVETYADLADAGFWRRANRERSIENWRTMLSTGVEAMLAEADGSIVGVAITAPAVPRGEVAPLRGLELTNLYVLARHQGSGIGQDLLDAVLPAGAAAQLWVARGNPRAVRFYERNGFTADGAEDDGSAFGGIAALRMVR
>NC_013172.1|WP_015775819.1|2008647_2010066_+|glycoside-hydrolase-family-32-protein
MTPTTLSPSRADLYRPRFHLTPESTWMNDPNGLIRHEGRWHAFYQNNPHGSLWGNLSWGHAVSDDLATWTHLPVALPCSEHEMIFSGSVVHDAENSSGLAAPGASGPLVAFYTSAYSPDHPTHPGLQAQSIAYSTDGGTEWTFYADNPILDRGSANFRDPKVFWHAESGRWVMVTVEAADQQVHLHTSANLLTWEEASVFTHPGLDGVLWECPDLLRVPVTGTADAPEGEAWVMVISTNPGGPAGGSGGYVLIGDFDGRTFTTQAQPQPLDLGQDCYAAVSFSGVEGAPVLLGWMNNWAYADQTPTDPWRSAMTLPRTLHLEPVAGGGLELLQHPIVPEAVRTVDLGAVATAVEPVVLDAVEPFRVQGTLGLRTPQRMVLRFGEEEAAPELVLSVDAEGRVVLDRSAAHGVDFAPEHGASAPYTPAAGSEEVAFDLVVDRSCVDLQLDGGRALVSQQIFPGAAEVSIRGESA
>NC_013172.1|WP_015775818.1|2007010_2008594_+|extracellular-solute-binding-protein
MLSRRQFTLGATALSLTAGLAACGRPSATETEDKSSDVGLTDSGLPVVTGDLTLRFGGGKSALAPDYESMELVKTWTEDSAITIDWVNEPDEVWAEKKNLLMASGELPDALFNTGLSDAEIAKYGANGTLVALEEMIPEHAPTLHGILEERPDIRSAITASDGHIYSLPSVEELGLVEFPSMLFLNTDWLEQHGLDMPTTVDEYHETLLAFKEDGPSGVLPLSFMGAENIADLIAAIGGQADNPDHRIVQDGKVLFTADKDGFADAIATLHTWYREGLIDQESFAQDYVKFIAKGKADPQTLGSFFFWEITEVVGYERADQYQIVPIFPGPDGVQRACVANNQEINRDAFAISRTNEYAAATLRWADMLFDPVMSAQANWGPLGIAQEMNDDGMLEQIPVADGESEQERRVKVAPGGPKIITAEDFETVVLPEPRAAERQEQIAEFYEPHRANEKYPPVMLSVEELNEISTIEADVKTLVDEKISTWIVKGGIEEQWDGYVAQLESIGLPEMIEVYQTAYDRYIDNA
>NC_013172.1|WP_015775817.1|2005989_2006937_+|carbohydrate-ABC-transporter-permease
MTTSTRTLPSNRTFRPRPQNVVNRVADPLFVIITYGIIALAILLIVYPLYFIVIASISDPNLVQQGKVVLFPRGVTFDGYLTIFGTSTIVRGFMNSVMYTAVGTFISVAMILFGAYALARKDMPGRNVFMILFVVTMFFDGGMIARYLVVKELGMLDTMWAVVLPGAVGVWNLVIARTFFEQNLSPELREAAQLDGASDFRFFFSIALPLSKPLIVLMAMIHIVANWNAFFDAMIYLSDESKYPLQLILRNVLIQSQASASGMDMASMDSTAAAQKMGELLKYSMIVVSTIPLLVAFPFLQRYFIKGATLGALKS
>NC_013172.1|WP_015775816.1|2005000_2005984_+|sugar-ABC-transporter-permease
MTTDTAVGPAPSQAPAPPEKAPRNAPRRSRLRRILQSWQLYVLLAPAVIYLIVFKYWPMYGAQIAFREYNPIDGFFWSPWVGLEHFETFISSFQFGRIVANTLTINTVGLLVAFPVPIILALIVNQLPSERFKRLTQTVLYSPSFISVVVVVGMIHLLFSPSSGLVNHMISAFGGEPIFFMGTPEWFRPLYIGSDVWQNAGFSMIIYLAALTAIDPSLHEAARMDGANRFQRIRHIDIPGILPVITILFILAVGNIFNLGFEKVYLMQTDLNLPTSEVINTYVYKVGLQGAQFSYSAAIGLFNSVLNLLLLVTFNWVAKKANQSSLW
>NC_013172.1|WP_164930230.1|2003995_2004997_+|substrate-binding-domain-containing-protein
MHDVAAKAGVSQAVVSLVLGGRYAGRASERTAERIREAADALGYRRNLQAKTLKTGVAEIIGLVGDEVATSPFSGQMIKGAQDLAWGEGNTLMTVDTGGDAALEAAAIETMLSHQVRGILYTAMYHRELEVPRAALETRAVTLNARDLTGSTPSVVPDEEKGGYDATRLLLEAGHTRIGMINIQPEEAIPAARDRRRGYQRALAEAGLPSSPELIIAGEGIHRSGDEGARALLALEEPVTAIFCGNDRTALGAYQALDELGLRIPEDISIVGFDDQDVLRDFFHPPLTTVQLPFLAMGEQAAALVLDPAAAAETHIIPCPVIHRGSVAPPKGR
>NC_013172.1|WP_015775814.1|2003379_2003766_+|hypothetical-protein
MNTLSSTRRSMSRAEALSWNPNWSVGDIRVIEENLDRLAARTFFRTRSNSTVTAQDDSGRSIMYLHPGYVTFPKGLAPEDRKDLEMHGFTLSTAQSRAASRAMPEETLSFCPGCFYALPATGVCDTCG
>NC_013172.1|WP_015775813.1|2002154_2003054_-|Ltp-family-lipoprotein
MESSVTSMPPSPQDPSSSDLPSGPEFSGPAHGAPPGEVPAPTAPARSGKKKGLIAAGCGCLALLVLAVGGCSALVFSGVGDDDPAASEETSAAEPAETPSDAAEASEDAPAEEAAEDETAAEDAPAEEEADEEPAEAPAEEDGADGDVPSDHASALKSAETYSDLMHMSKQGIFEQLTSEYGDQFSEEAAQYAVDTLDADWNDNALQSAESYSETMHMSKQGIFEQLTSEHGEQFTEEQAQHAIDTIEADWNENARQSALVYRDTMDMSPEAIRDQLSSPYGDQFTQEQADYAVEHLDD
>NC_013172.1|WP_015775824.1|2014027_2015593_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MPSPDHTASPAASADRDPRLDRPWPALWSIVLGFFMILVDTTIVTVAIPRMQQDLDTDLTSLLWVTSAYLLAYAVPLLITGRLGDRYGLKAVYMVGLVVFTASSLWCALAGDVGMLIVARVVQGLGAGVMTPQTMSMITRMFSPQQRGRAMALWGATAGVASLVGPLLGGVLVDGPGWEWIFLVNVPVGILTLLLVQRNVPRFSRRAHSFDWLGVVLSAIGLFLLVFGIQEGNTYDWGRITDSLRIGPLETGMPVSVPGLIIAGVVALVVFVVWQARNRREPLVPLSLFRDRNFSVASLAIAMMGATVLTLAIPATLFFQQVLGMTPTQAALMTAPMAVVSLVLAPPVGRWMTLHDPRWMALGGFASLAGGLLWLSRLMTPETPFVLLLLPFLLVGLGNAFVWGPLSLTATRNLPPSLAGAGSGVYNETRQIGSVLGSAAIATLVSDRLAARIGEATGGAGGTAPAGAEGGTGTLPEALHAPYAAAMSDAMLLPVGLAAVGVLAALLIGKPVDTGVWARDE
>NC_013172.1|WP_164930232.1|2015603_2017115_-|polysaccharide-pyruvyl-transferase-family-protein
MRLGKTPFDVVDPFLTLERNLLGTNSGNLVYGAAAHKLFSTADTIVDANHYRINAGMAAQVNDEYDGFILPLANAFRPEFEGQLLRTAQFLERLTIPFLMLSGGAQLPLDGDPAALKAMEPTVKRFARAVLNGSSALSVRGEMTADYLASLGFRDVEVVGCPSLALHGPGHRVEVPETLRHGAPIAYNLETKDPFGGDLVEDAEARYAATYIPQEHGTLELMLWASEPYVANDPRLPLERSHPQFTASRAEFFIDAHPWFDRLATMDFSFGARAHGNIAAILAGTPAVMLAHDSRTLELARYHGIPSLVRGADGQPGSVQELFSHADFTEFNRGHAERFETLSRFIHDNGFSHIYDPGQEAALAAYEQRVAETEFAPAVRPTWLEDPPATVQRHAVLQDREARRKKEQAELRRTTAARAAKSAERITALERRLDAAEADLAATRRAVESAERRAAAAEQRLTRTEKKLTKVARQAGDAFHRAERAVRIPTRLKDAVSRGRRDR
>NC_013172.1|WP_015775826.1|2017311_2019207_+|DNA-helicase-RecQ
MSIPPAADQISARREGDAGQADRALEILSSVFGYDSFRGDQRAIIEQVAAGGDAVVLMPTGGGKSLCYQIPALLREGTGIVVSPLIALMADQVAALEGVGIRAAYLNSTLELDEARAVEQQLLAGELDLLYMAPERLVLPRTQDLLRRAHLALFAIDEAHCVSQWGHDFRPDYLGLSVLAEAFPTVPRIALTATATEATHRELTERLQMQEAEHFVSSFDRPNIQYRIEPKASPREQLLRLITTEHEGESGIVYCLSRKSVEQTAEALVARGIPALPYHAGLDAAVRQDHQERFLRAEGLIIVATIAFGMGIDKPDVRFVAHLDLPKSIEGYYQETGRAGRDGQPSTAWMAYGLGDVVSQRKFIDTGEGSEQFKRNARSHLDAMLALCETVSCRRVQLLRYFGQDTEFTSCGNCDTCLSPPQTWDATVAAQKLLSALIRLDRERGQKFGSGQVIEVLLGRENTRSTQSRHHELSVWGIGEELSEKEWRTAIRQLLARGIVEAEGDYGVLIPGPQAGPVLRGESTVELAVDRAPQRSSRSGGRRAAGASRAAESLEPAQRERFEALRAWRTAVAKEKQIPPYMVFSDATLVGIVEARPASVAQLGAVSGVGAKKLAEYGEAVLEALPDAPTG
>NC_013172.1|WP_015775827.1|2019266_2020388_+|hypothetical-protein
MTAPSPMPQGSYTPPPAEPVSKSSSRRNLIIAGALAGGGCFLVLLVVLVLVIVLVMRGGGGTAAGADGEESSIASLSPEEQATALVADYFDALSTGDAENALELLGPQDDPDITTLPVEAYSQALELAPVAEVEVGTPVLDESGLISGEVPVTFTVGEQTVSDAYSVHDYDDDGVLELTGSGADETVPDNVTGLDTTLNGVEVTAGQRVLLLPGGYELAYGSEHFAPTSTDPLLVGEQYGHVDWPDPELTEDGQTAFRGAVQEAVDACLTETTLAAGCGMTPVPETSNDGWTMVEDTVQRSISEDTQRTIDTMEGTPSYDEPTYVEGSSIGTVETTIECTKDDQKGTCELWLGGGMGRPHVDMSDPELPVTWG
>NC_013172.1|WP_164930233.1|2020391_2021513_-|metallophosphoesterase
MGLAGAEATPLPARRPRPDNGIVRNQLRFHDDGTFTAVQFNDTQDSHRTDERTIALQEAVLDDVRPDFVVINGDVIDGSPTTALEAKQALNNVVRPMEDRGIPWALTFGNHDEDSSERTGLDEEAYLDFVRQYAHNVNTRQAEGITGSGNQVLTLASADGTREAFALWLLDSGRYAPEQIAGQDFEGYPDWDWLRPDQVGWYLSTSQELERRNGALVPGLVFQHIALWEHRFAWFASVDSRTDADHERAVTKHRIEGERNEEECPGPVNSGMFAAMLHRGDVKGLFVGHDHANSYVADYYGILLGYAPATGFAPYALDGEEQHRLRGARVFHLDENVEGVLAGTELRLAADYGIDLTPEPRPGEPADFPDGVR
>NC_013172.1|WP_015775829.1|2021727_2022945_-|DUF1624-domain-containing-protein
MTSSAPSRPAARPAPEPDRAPGRAGSSPPGGARTATARIEALDLARLLAILGMMAVHLLAPLAQDPASTGIQGHLARAADARAAGSASTLFAVIGGCSLVLATRRPLARGERGRAVASVLVRGACVTLLGLVLELAPTSVMVVLVPFGLSMMLTAPLLLVPSRVLVPLLGVLALGGAPLAAAVPGPVEFGTVTLLSLDDPVGVLRGLVLTGQYPLITWVPYLLLGIVLMRGLLRAQQHGDPVRSSRQMLLAGAVTAAAGHALPLLAAALGHATPGAWYTAAPHTGTLGDMLATAGLSAAVLGALTWALPAGRQLQSRTARTLRAAGAAPLSIYVGHVLLTTAALLLAVVASGGELTSMPWYVAGVGVLGVHVVLTLALGAVLAARGGRGPLEALVARTVRRLTRV
>NC_013172.1|WP_015775830.1|2023036_2024743_-|ABC-transporter-ATP-binding-protein
MTAAHTGTQGGPRLALRELDVHFATDAGDVHAVDGVSLEVAPGEILAIVGESGSGKSVTARSVLGLLPETAEASGAVLVSGTDLVGLSAARLRALRGEDVSMIFQEPSSALNPVFPIWWQLGEGLRAHRPKITRKEIRAEAVRALDSVGIPDAAERIDRYPHEFSGGQKQRIMIAMALALGAELIVADEPTTALDVTVQAEILDLLREIRRRHGTSIIVITHNMGVVADLADSVAVMHHGKIIERAGVQELFAAPREAYTKKLLAAVPHLGRDSAWTALDPAQRAALEEAAPVVVAKDLVIEYPGRLGRAPFRAVNGVDFEIRAGEVFGLVGESGSGKTTIGRAIAGLERTTGGSLSVLGHEMNGMREKAFKPLRRRIGFVFQDPATSFNPHLTIEQCIAEPLIVHEEHLSPAERGARVRALLEAVELPGTYAGRYPHELSGGQRQRISLARALVLEPELLIADEPTSALDVSVQATVLDLFRELQQRLGFAALFISHDLAVVDSLAHRIGVLFRGDLVEDGHGPDVLQRPRHQYTRKLIASLPVPDPVEQAARREAFAREWGGDAQG
>NC_013172.1|WP_015775831.1|2024739_2025771_-|ABC-transporter-permease
MTLSNPEPVGEGDPGATGLAAEASQVAERRRAPWYLRLPILSHLRSSVGLQRGMLVTGLVLVGLLLLTALLAPLLAPHGFADTGSDGVRFGTQQPPSAAHPLGTTVTGFDVLSRVIWGTRTAVAVMACAVAASLFIGVAIGLVSGYVGGWLDRVLVMVADAIYAFPSLLLAIVMSIVISGGQSDAWGGILAAALSITVVFIPQYFRVTRAEVVRLKAEPFVEAAKVVGTGHRRIMGTHLLRNATRTLPLIFTLNASESILTLAALGFLGFGIEPTSASEWGYDLNRAMADATSGIWWTGMFPGLAIALAVLGVTLVGESVNDLNDPRLRTRRSRRRARKEAAS
>NC_013172.1|WP_015775832.1|2025772_2026855_-|ABC-transporter-permease
MSTALDPEAEDTPRRTRRRASGGLGRYILVRFLLIIPTVLILMTMVFFLMRITGDPITAALGGRLTPDQLAQRRAEAGYDRPLIVQYFDYLGGVLRGDFGTTYTDNTPVTEVLTTYGAATFELVVYSLVVALLLGVPLGMIAARTRDRWPDAVLRIIAILGYATPVFFVGLLLKLVFSVGLGWLPVAGRLSTSGQITMSTILNPSPFSLLDALRLGDTELLRDVLGHAVLPAVALGILTGGVFLRLVRTNMIGTLEMQYIESARSRGVAETRLTTRHGLRPALIPIITVMGMQVAMMLGGAVLTETTFEWNGLGYMLAEYMKARDYIAVQGIVMMLAVIVALSNFVVDVIAALIDPRVRY
>NC_013172.1|WP_015775834.1|2028691_2029654_-|hypothetical-protein
MAPTDVITWLLDTDPALRWQVERDLLDAPEQQWRDTRARIPHEGFGAALLERQDPETGLWAGGAFFPAGYLEDPESELLPGQPWTATTWSLTTLREWGMDPAPLTARDTAAKLARNARWEFDPTLPYWGGEVDVCINAMTLANGLWLGADVESLATWFVEHRMAEGGWNCEWENGSTRASFHSTLNALRALHAHEQRTGGTAATAEVQRAGEEYLLRRNLTRRLTTGEIVGPWVDHFLYPPRHIYTALGALDHFRAAGRRDPRMQEAITLVQDAQQPDGTWLQQHVLPGEVWFEIDVGVGQPSPWLTAQALRVLRWWNEG

Crispr_ID: NC_013172_7

• CRISPR_ID: NC_013172_7
• CRISPR_location: 2580823-2580923
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NC_013172_7

Consensus_repeat	Method
GCGGTGACGGGTCAGCGAGCCGTGG	CRISPRCasFinder

spacers of NC_013172_7

>7.1|2580848|51|NC_013172|CRISPRCasFinder
AGAGGACCGACGCTCCGTGACGGGCCAGCGAGCCGTGAAGAGGACCGGCGG

CRISPR arrays and Neighbor proteins around NC_013172_7

CRISPR arrays

The CRISPR arrays of NC_013172_7

>merge|NC_013172|7|2580823-2580923|CRISPRCasFinder
GCGGTGACGGGTCAGCGAGCCGTGGAGAGGACCGACGCTCCGTGACGGGCCAGCGAGCCGTGAAGAGGACCGGCGGGCGGTGACGGGCCAGCGAGCCGTGG

>NC_013172|7|7|2580823-2580923|CRISPRCasFinder
GCGGTGACGGGTCAGCGAGCCGTGG	AGAGGACCGACGCTCCGTGACGGGCCAGCGAGCCGTGAAGAGGACCGGCGG
GCGGTGACGGGCCAGCGAGCCGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_013172.1|WP_015776308.1|2587217_2587709_+|transcription-elongation-factor-GreA	unknown	unknown	gnl|CDD|234693
NC_013172.1|WP_015776310.1|2589393_2590275_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_013172.1|WP_015776307.1|2586532_2586925_+|DUF4307-domain-containing-protein	unknown	unknown	gnl|CDD|379491
NC_013172.1|WP_015776292.1|2570289_2571375_-|redox-regulated-ATPase-YchF	unknown	unknown	gnl|CDD|236583
NC_013172.1|WP_015776306.1|2585389_2586301_-|mycothiol-conjugate-amidase-Mca	unknown	unknown	gnl|CDD|132487
NC_013172.1|WP_015776309.1|2587791_2589225_-|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NC_013172.1|WP_015776291.1|2569826_2570186_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NC_013172.1|WP_015776297.1|2575924_2576239_+|exodeoxyribonuclease-VII-small-subunit	unknown	unknown	gnl|CDD|179195
NC_013172.1|WP_164929994.1|2576263_2576983_-|DUF4245-family-protein	unknown	unknown	gnl|CDD|379430
NC_013172.1|WP_164930272.1|2579850_2580576_-|hypothetical-protein	unknown	unknown	gnl|CDD|380141
NC_013172.1|WP_015776295.1|2573343_2574357_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	unknown	unknown	gnl|CDD|234893
NC_013172.1|WP_015776303.1|2583178_2583937_-|di-trans,poly-cis-decaprenylcistransferase	unknown	unknown	gnl|CDD|237825
NC_013172.1|WP_015776294.1|2572042_2573242_+|DNA-recombination-protein-RmuC	unknown	unknown	gnl|CDD|376878
NC_013172.1|WP_015776299.1|2577197_2578109_+|carbohydrate-kinase	unknown	unknown	gnl|CDD|238572
NC_013172.1|WP_015776300.1|2578206_2579613_+|class-II-fumarate-hydratase	unknown	unknown	gnl|CDD|234779
NC_013172.1|WP_015776304.1|2584154_2584985_+|hemolysin-III-family-protein	unknown	unknown	gnl|CDD|224191
NC_013172.1|WP_015776311.1|2590259_2591972_+|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_015776293.1|2571436_2571883_-|hypothetical-protein	unknown	unknown	unknown
NC_013172.1|WP_015776302.1|2581338_2582649_-|PhoH-family-protein	unknown	unknown	gnl|CDD|224787
NC_013172.1|WP_015776305.1|2585009_2585393_-|hypothetical-protein	unknown	unknown	gnl|CDD|371058

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_013172.1|WP_015776291.1|2569826_2570186_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	6.2e-14	47.1	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_013172.1|WP_015776308.1|2587217_2587709_+|transcription-elongation-factor-GreA	gnl|CDD|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	3.53394e-49
NC_013172.1|WP_015776310.1|2589393_2590275_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.77125e-78
NC_013172.1|WP_015776292.1|2570289_2571375_-|redox-regulated-ATPase-YchF	gnl|CDD|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NC_013172.1|WP_015776306.1|2585389_2586301_-|mycothiol-conjugate-amidase-Mca	gnl|CDD|132487	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca. Mycobacterium tuberculosis, Corynebacterium glutamicum, and related species use the thiol mycothiol in place of glutathione. This enzyme, homologous to the (dispensible) MshB enzyme of mycothiol biosynthesis, is described as an amidase that acts on conjugates to mycothiol. It is a detoxification enzyme. [Cellular processes, Detoxification].	1.26923e-134
NC_013172.1|WP_015776309.1|2587791_2589225_-|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	4.96226e-54
NC_013172.1|WP_015776291.1|2569826_2570186_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	5.8886e-17
NC_013172.1|WP_015776297.1|2575924_2576239_+|exodeoxyribonuclease-VII-small-subunit	gnl|CDD|179195	PRK00977, PRK00977, exodeoxyribonuclease VII small subunit; Provisional.	3.08069e-20
NC_013172.1|WP_164929994.1|2576263_2576983_-|DUF4245-family-protein	gnl|CDD|379430	pfam14030, DUF4245, Protein of unknown function (DUF4245). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 188 and 235 amino acids in length.	1.54134e-25
NC_013172.1|WP_164930272.1|2579850_2580576_-|hypothetical-protein	gnl|CDD|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	7.31177e-06
NC_013172.1|WP_015776295.1|2573343_2574357_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	gnl|CDD|234893	PRK01045, ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed.	0
NC_013172.1|WP_015776303.1|2583178_2583937_-|di-trans,poly-cis-decaprenylcistransferase	gnl|CDD|237825	PRK14828, PRK14828, undecaprenyl pyrophosphate synthase; Provisional.	5.39871e-114
NC_013172.1|WP_015776294.1|2572042_2573242_+|DNA-recombination-protein-RmuC	gnl|CDD|376878	pfam02646, RmuC, RmuC family. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures.	1.89736e-108
NC_013172.1|WP_015776299.1|2577197_2578109_+|carbohydrate-kinase	gnl|CDD|238572	cd01167, bac_FRK, Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.	3.83672e-75
NC_013172.1|WP_015776300.1|2578206_2579613_+|class-II-fumarate-hydratase	gnl|CDD|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NC_013172.1|WP_015776304.1|2584154_2584985_+|hemolysin-III-family-protein	gnl|CDD|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	3.79209e-45
NC_013172.1|WP_015776307.1|2586532_2586925_+|DUF4307-domain-containing-protein	gnl|CDD|379491	pfam14155, DUF4307, Domain of unknown function (DUF4307). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 132 and 153 amino acids in length. There is a single completely conserved residue C that may be functionally important.	3.61253e-25
NC_013172.1|WP_015776302.1|2581338_2582649_-|PhoH-family-protein	gnl|CDD|224787	COG1875, COG1875, NYN ribonuclease and ATPase of PhoH family domains [General function prediction only].	0
NC_013172.1|WP_015776305.1|2585009_2585393_-|hypothetical-protein	gnl|CDD|371058	pfam10446, DUF2457, Protein of unknown function (DUF2457). This is a family of uncharacterized proteins.	1.14719e-05

Protein sequences

>NC_013172.1|WP_164930272.1|2579850_2580576_-|hypothetical-protein
MRPTCLDGASLHGLWTPPHPGAHVFRPRQLHAGEELRGARVHPVRRRSGTVITLAEEELVLHGPALRSWPDHDPVPGLALVLTHAAHCLPVEKTAVLFESGLQRGLLTRREAERILASLPQRIRRPLSRIREDAESGTETIVRWWMESRRFPVRPQVLFPEGRRRMDLLVGKSWVIECDSREFHDDPLSYDVDRARDLYLASRGYRVTRLSWEQVFLRWEETQAMLLAILRRGEHRDPPSR
>NC_013172.1|WP_015776300.1|2578206_2579613_+|class-II-fumarate-hydratase
MNQSTPAQGYRIEHDTMGEVRVPASALYRAQTQRAVENFPISGQGLEPAHIHALAQVKKAAARANKDLGVLDGAIADAIVAAADAVIAGEHDDQFPVDTYQTGSGTSSNMNMNEVLATLATNSGVETHPNDHVNCSQSSNDVFPTSVHVAVTQGVVSTLLPALAHLAESLETKAEAWKSVVKSGRTHLMDATPVTLGQEFGGYAASIRYGIERVEAALPRTAEVPQGGTAVGTGINTPIGFPQKVIANLVEQTSLPLTEARDHFEAQSNRDGLVEMSGALRTIAVSLTKICNDVRWMGSGPNTGLGEIAIPDLQPGSSIMPGKVNPVIPEAVLMVCAKVVGNDAAIAWGGAQGSFELNVQIPLMGTSLLESIRLLANASTVLADKTVDGLVANEEKARFYAEASPSIVTPLNKLIGYENAAKIAKHAVAERISVREAVIALGFLERGELTEAQLDEALDVLSMTAPKA
>NC_013172.1|WP_015776299.1|2577197_2578109_+|carbohydrate-kinase
MTARFLIAGEALTDIVIDAANTQREHPGGSPMNVAVALSRLGHEAHLLTRIGNDARGDAIRAHLDASGVQLTPGSSVEAATSTALARLDANGAATYEFDLLWDPRPAGLPEHVDAVHTSSIAAVLEPGAETVLDVLRRRRDGSTISYDPNARPTLMGEAETVRAQIEHTIALCDVVKASDEDVAWLYGTDDVEDVVASWRELGPALTVLTRGDEGAVGFAATGRVQVSPVVVDAVDTVGAGDTFSAGILDALAAKDLLGAEKRPALAAMPSDDVASVLRHAAALAAITVSRAGANPPWSHELS
>NC_013172.1|WP_164929994.1|2576263_2576983_-|DUF4245-family-protein
MREAPQDTPETTDRTSAMPPDESAPVEPAPTVPASGEPAAADEAGTRAEPAPQPKSAYELPSRKNTVLRNMVWALALTMAVVVVVGIAFFGVGSDGERERLENSEVDVAASAERAEGVAPFPVALPALGDEWIERSARFADGQNPQWVVQYSSPEGQLITLRQESELGAPMLSSSLPGSTVEDEFALGGAQCTALSGGEKGAQQQGIACEGEDWGFVVHGAAERGELDEVATAAVDSLG
>NC_013172.1|WP_015776297.1|2575924_2576239_+|exodeoxyribonuclease-VII-small-subunit
MSPSTDTSPSPAEGDPADAATVTPVEGEQPLPSDIAELSYEAARDQLVEVVRRLESGQGGLEDSIALWERGEMLARRCQQWLDGARERLDDAVAARRSADSDAQ
>NC_013172.1|WP_015776295.1|2573343_2574357_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase
MGGVSTGTVLLAEPRGYCAGVDRAVVAVERALEHYDETIYVRHEIVHNKFVVDRLKEKGAVFVEEVDEIPEGSLVIFSAHGISPKVREMAEERNLRTIDATCPLVTKVHKEAVRFARQDYDILLVGHEGHEEVEGTAGEAPEHVQIVNSPDDVHKVTVRDPERVVWLSQTTLSVDETMETVDKLRERFPTLQSPPSDDICYATQNRQVAIKKIAPDADLVLVVGSPNSSNSVRLMEVAKEAGAKASHRIDSVHELQEEWFEGVETVGVTSGASVPDVLVQQLLNVLAERGYGDVKPVRTATEDLMFSLPRELRQEMKNRGATDSRKKPTGESATAES
>NC_013172.1|WP_015776294.1|2572042_2573242_+|DNA-recombination-protein-RmuC
MLLLGLILGAALGALASWLVMRERARVAELRHHSSADSAGQLLRLADERHERDVARRDAAEEEREAELQRTLAPITATLTQLERSLARSEAARIDAEGALRSHLSQLAQRAQSLETGTSALTAALRAPTARGRWGEVQLRRIVEAAGMLEHVDFTEQLPGTRADGEKGQRPDLVVHLAGDRHVVIDAKAPMDAYLDATEETDPARAAARRKAHAKALRHHVGVVSSKAYWKALGDTPEFTVLFVPSDGVLAAALETDPELLEDAFARDVVIASPATLVALLRTVAHTWRTDALNRDAREVLDAGRELHHRLGTFTGHLGKVGRSLDSSVAAFNEAVGSLQSRVMVTARKFEELGLSGTGLDEVEQLTQRARTLDDAQIADLAGGAQASPPQRRGAPRAG
>NC_013172.1|WP_015776293.1|2571436_2571883_-|hypothetical-protein
MFLRALVLLPRTAQAEASQGYELMSEEFTRLSGADAEALDVDVGAPLGTVRTVTCAVEPSDRGGFVADRRNDCTLRELEVRAVPQDAPEGADRAGTRLRDAQAPPDGARLLVVVRHARISSSSLGCLPLPVFCEPTADEPQLPDALKG
>NC_013172.1|WP_015776292.1|2570289_2571375_-|redox-regulated-ATPase-YchF
MALTIGIVGLPNVGKSTLFNALTRAEVLAANYPFATIDPNVGVVPLPDPRLAELAKVFGSQKLLPATVSFVDIAGIVKGASEGEGLGNKFLANIREAEAICQVTRAFADPDVTRVEGSVDAAGDMETITTELILADLQTIENSMQRLEKETKRGLLDAAVLENVHKAKALLETGKTLYQGAKDAGIDTAALRDLQLMTAKPFIYVFNTDEEGLADTAMQERMRALVAPAEAIFLDAKFESELIELDEEEAAEMLESTGQEESGLDQLARVGYETLGLQSYLTAGPKESRAWTIPKGATAPQAAGVIHTDFERGFIKAEIVSFDQLMEAGSMAEAKAKGWVRMEGKEYVMQDGDVVEFRFAL
>NC_013172.1|WP_015776291.1|2569826_2570186_-|winged-helix-turn-helix-transcriptional-regulator
MLTIASRLDVMNRLGRAMADPTRSRILMTLLSGPSYPAVLSRELELTRSNVSNHLTCLRDCGIVVAEPEGRQTRYEIADPHLAAALVALVDVTLAVDERAPCVDSTCMVPGCCGAGADA
>NC_013172.1|WP_015776302.1|2581338_2582649_-|PhoH-family-protein
MLAEIETGVITYVLDTSVLLSDPQSLHRFAEHDIVLPIVVVTELEAKRHHPDLGYFARQALRILDDLRAQHGNLSRPLPIGKDGGHVHVELNHMSTASLPDGFRLGDNDTRILAVAKNLQHEGKNVVLVSKDLPMRIKASASGIHAEEYRAELARDRGYTGMVATTVGEQEMTDLYDGETLSLPEIAHLPVHTGLTITSPRGSALGRITREKQVTLVPGDQTVFGVSGRSAEQRVAIDLLQDESIGIVSLGGRAGTGKSALALCAGLEAVLERRTQRRIMVFRPLFAVGGQELGYLPGDQGEKMGPWGQAVFDTLGSMVSQNVIDEVLSRGMLEVLPLTHIRGRSLHDAFVIVDEAQSLERNVLLTMLSRIGQNSRVVLTHDVAQRDNLRIGRYDGIASVVEALKEKDLFAHVTLQRSERSKVAELVTHVLDEPLP
>NC_013172.1|WP_015776303.1|2583178_2583937_-|di-trans,poly-cis-decaprenylcistransferase
MDDDGLLYRVYERRLTRELEAFDLPQHLGVIVDGNRRWAKEAGETTEHGHRVGAAKILEFLSWCDDLDIPLVTVWMLSTDNLRRPPEELTALYEIIGATIGRIIDAGYCVRLTGNAEALPQEMRADISREQEQTAPESRLTVNVAIGYGGREEIVDAVQELVRDLAAQGLDGDGIAAGISIGSIAEHLYTRGQPDPDLIIRTSGEQRLSGFLLWQSVHSEYWFCETYWPGFRRVDLLRALRDFCRRERRFGV
>NC_013172.1|WP_015776304.1|2584154_2584985_+|hemolysin-III-family-protein
MDNGHHRDARAQGAFTSEEEVEAAEAVAESGGTRLPSDDDLPTAETFPFAPRTLTRAMARRATQLGLQLPKPRLRGMLHLIAFPTTLVIGLLLVAVGETFATRLACAVFVLTAGMLFGISAVYHRGTWTPQRAIMLRRFDHANIFLIIAGTYTPIAVTLLAPRQALTLLLIAWGGALVGVCFRLFWTAAPRWIYVPAYIALGWVAVFYMPALHAGGGWPVVWLLVIGGLAYTAGAVMYALKRPNPSPAWFGFHEIFHAGTLIGFGCHFAAVAVAVL
>NC_013172.1|WP_015776305.1|2585009_2585393_-|hypothetical-protein
MSGAELLLALGELGAAPSPSDGGEFNQVTVSPGLPGFFAMFALAVVVVLLAVDMTRRTRRVQAQARVKERMEAQQEAEERAAQEQEAAEGDEDTLDADADDADDADGDADVDPDADADAQADDDDPR
>NC_013172.1|WP_015776306.1|2585389_2586301_-|mycothiol-conjugate-amidase-Mca
MTVQLPAPDEPLRMVAVHAHPDDESSKGAGSTARYVREGAQVTVITCTGGERGDVLNPRLRDDPSVTVEALPEIRRQEMARAQEILGVDHEWLGFIDSGLPEGDPLPPLPAGSFATLPVEEAARPLVEAVRRLRPHVMTTYDENGGYPHPDHIQTNRISLAAFDLAADPQFAPELGEPWAIAKLYYINGFHRQRFAAVSRHLRSEGTPNEMLDQMLQHYDESHDRLLTTRIDVRDYLAIRDDALRAHATQVDPEGPFFRISHEAETAAWGTEDYELHISRIPVKLPEDDLFAGLRRERVEARP
>NC_013172.1|WP_015776307.1|2586532_2586925_+|DUF4307-domain-containing-protein
MNAATDRHADRYGRPLVSRRTARVLIAVAAAVFLAAIAILGISTGGTSVSSELISYDHIAENVVAVDFQVTMDPGTEASCQIQAMNSGRAQVGFVEVDIPAQESRLSAHHVEISTQGEAVSAEIIDCSPR
>NC_013172.1|WP_015776308.1|2587217_2587709_+|transcription-elongation-factor-GreA
MSSQPNGAWLTQDAYDRLAKELEELEGPGRTEIAERIAAARDEGDLKENGGYHAAREEQGKMEARIADLQRLLKNAVVGEAPKDDGVVEPGMVVVISMAGKERTFLLGNREIADGDEDLEVYSSESPLGSAIHGSRVGDTVDYTAPNGKSFPIEIRKATPYKA
>NC_013172.1|WP_015776309.1|2587791_2589225_-|AI-2E-family-transporter
MSKLRPTPRAPGLAPEVEEIPLGIRRAAAWSWRLIVVIAASALILWGLLQITTLVIPVLIAVLLAAMLNPVVKVLTRYTFLGRTAASGVALLGLLLVIAGMFTLAGRQLFAQFADIQEKAVTGFQSLTDWATSTFQIDAPMVDAAIDEGLTQLQDNSDQLVSGALGTAAVLGNVATGIVICLFALFFFLAGGSSIWRWVVGLLPPAARVPTHEAFRRGWKALSAYIRTQILVAGVDATGISIGMVALGLGSYAVPIWLLVFLFSFVPLVGAIVSGAIAVLLVLVLNSWIGAIIMLAIVLVVQQAESNILQPFLMGKAVELHPLAVLLGVAAGVMVANIAGALFAIPLIAFVNATLLYLVGRDPAPDLGEDRASAEHFAALTRTQPAPVQGGTEGAERRSAFSALVPGAKTAPAQPSASQERAPQEPTPQEPAAQESAVQSSAGTGSSAPQAAPSQETPAQPPSPQDPPAQDTPRDGD
>NC_013172.1|WP_015776310.1|2589393_2590275_+|ABC-transporter-ATP-binding-protein
MHSEHPFPSEGHPAPAPSADRAVAQGPVAGIAAPVSADAAVPESTALSLRGLRKSFDGTEVVHELSLDVPRGSFYGIVGPNGAGKTTTLSMATGLLRPDGGTAHVLGHDMWAVPEQAKARLGVLADGLRTFDRLTGRELLTYVGLVRGMEPAVVEERMESLLTALDLAGEDGKLVVDYSAGMTKKILLACALLHAPRLLVLDEPLEAVDPVSAQVIRKILTAYVDGGGTVVLSSHVMELVEGLCSHVAIIARGELLADGTLDQVRQGGSLVQTFIDLVGGGDVAEGSLAWLES
>NC_013172.1|WP_015776311.1|2590259_2591972_+|hypothetical-protein
MAGVLSSEHVRTASAQGVHHGEISAKALLRMQLRLKWTLWKRSYRKNVGKLIGTIIGALYGLGGLVSLVFLFLGTTLWAGEGETFPLVVRGLGALTVLAWFLIPVLAFGLDDTLDPRAFALFPRSAKELQPGLFAAAALSFPSLLTLAAVAIATGFELLWLIVFGQGAVWIVLGALALIPANLAAYCLCLLLPRAWFAHSASRTSSRSGRELGGIFGFVVMFAAIYAFSLGAQRIGDIDVELLGEWAPRIVGVVAWTPVGALFAVPMDLAEGHVLTALARAVIGAATIVLVWRWWRRSIDAALTSALSGDASSGDAKVSPLVPRFLRPGPFGAVMGKSLRYWRRDTRYLAALGIYPVVLVFFAAMGFMLPESRPMMLGMAVFMCGMSGISLANEIGFDGPSGWVNIVTALPARANLLGRIAAMAVLMVPGAVVITTVIPLLFGMGELVPLAVMGSLGAMICGWGISMVVGVLLPYPSSPPGTNPMKDKSASSSNAMLAMAVAMLGIFVPLLPAIGVGIWGAVVGSLPLMMLAGALALLAGAAVFLVGLRIAEVRLEARYPDVFQKVRDHL

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	362565-362589	3	0.88
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	2379-2403	3	0.88
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	CP000665	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA04, complete sequence	13846-13870	3	0.88
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	226801-226825	3	0.88
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	76313-76337	3	0.88
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP014797	Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence	139369-139393	3	0.88
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	1394850-1394874	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	737541-737565	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP049360	Deinococcus wulumuqiensis R12 plasmid unnamed3, complete sequence	22477-22501	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	53709-53733	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	AP021851	Deinococcus grandis ATCC 43672 plasmid: pDEGR-2 DNA, complete genome	315053-315077	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP048428	Rhizobium daejeonense strain KACC 13094 plasmid unnamed4, complete sequence	54438-54462	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	MN813693	Mycobacterium phage Imvubu, complete genome	37860-37884	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP021407	Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence	74934-74958	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP053905	Hymenobacter sp. BRD67 plasmid unnamed1, complete sequence	98702-98726	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	561394-561418	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	368325-368349	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	616994-617018	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	942976-943000	4	0.84
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	142254-142278	5	0.8
NC_013172_3	3.1|853335|25|NC_013172|CRISPRCasFinder	853335-853359	25	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	530323-530347	5	0.8
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	MN284895	Mycobacterium phage Marshawn, complete genome	19575-19605	5	0.839
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_CP015097	Pelagibaca abyssi strain JLT2014 plasmid pPABY7, complete sequence	17767-17797	6	0.806
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	JN698993	Mycobacterium phage Firecracker, complete genome	31458-31488	6	0.806
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	KT281796	Mycobacterium phage Zakhe101, complete genome	31360-31390	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	MN428058	Mycobacterium phage Krili, complete genome	30772-30802	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	MH590592	Mycobacterium phage Ryadel, complete genome	32072-32102	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	MT818425	Mycobacterium phage NiebruSaylor, complete genome	30644-30674	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NC_022325	Mycobacterium phage Dylan, complete genome	31356-31386	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	289770-289800	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	KJ944841	Mycobacterium phage Cheetobro, complete genome	21273-21303	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	KY087992	Mycobacterium phage Mitti, complete genome	21189-21219	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	MF140402	Mycobacterium phage Chancellor, complete genome	21276-21306	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	MN693683	Marine virus AFVG_250M978, complete genome	9674-9704	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	KT361920	Mycobacterium phage Slarp, complete genome	21276-21306	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	KX621007	Mycobacterium phage Taquito, complete genome	20885-20915	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	MH051258	Mycobacterium phage SamScheppers, complete genome	20804-20834	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_CP035512	Haematobacter massiliensis strain OT1 plasmid pOT1-2, complete sequence	267343-267373	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP025513	Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence	315010-315040	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	653362-653392	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1245710-1245740	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	68938-68968	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	1268334-1268364	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	243846-243876	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP030763	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence	352228-352258	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP048424	Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence	24485-24515	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1075828-1075858	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	AP009146	Sodalis phage phiSG1 DNA, complete genome	22393-22423	7	0.774
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	DQ785801	Sodalis phage phiSG1, complete genome	14461-14491	7	0.774
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	43440-43470	8	0.742
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	677701-677731	8	0.742
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	KY092482	Streptomyces phage Mojorita, complete genome	35459-35489	8	0.742
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	KY092480	Streptomyces phage Picard, complete genome	35657-35687	8	0.742
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	447350-447380	8	0.742
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_CP010721	Phaeobacter piscinae strain P18 plasmid pP18_f, complete sequence	40003-40033	8	0.742
NC_013172_5	5.5|1536212|31|NC_013172|CRISPRCasFinder	1536212-1536242	31	NZ_CP016354	Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence	47010-47040	9	0.71
NC_013172_5	5.6|1536266|31|NC_013172|CRISPRCasFinder	1536266-1536296	31	NZ_CP041206	Rhizobium sp. NIBRBAC000502774 plasmid pMK-3, complete sequence	258116-258146	10	0.677

1. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 3, identity: 0.88

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggtggagcggcgcaggcggcggg	Protospacer
*******  *************** 

2. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 3, identity: 0.88

gcggtggcccggcgcaggcggcggc	CRISPR spacer
acggtcgcccggcgcgggcggcggc	Protospacer
.**** *********.*********

3. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to CP000665 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA04, complete sequence) position: , mismatch: 3, identity: 0.88

gcggtggcccggcgcaggcggcggc	CRISPR spacer
tcggtcgcccggcgaaggcggcggc	Protospacer
 **** ******** **********

4. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.88

gcggtggcccggcgcaggcggcggc	CRISPR spacer
acggtggcccggcacaggtggcggc	Protospacer
.************.****.******

5. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 3, identity: 0.88

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggtggccaggcgcaggccgcgcc	Protospacer
********* ********* *** *

6. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP014797 (Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence) position: , mismatch: 3, identity: 0.88

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggtggcccggcgcaggccaaggc	Protospacer
******************* . ***

7. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
tcggcggcccggcgcaggcggcgca	Protospacer
 ***.******************  

8. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
tcggcggcccggcgcaggcggcgca	Protospacer
 ***.******************  

9. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP049360 (Deinococcus wulumuqiensis R12 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
ttggcgacccggcgcaggcggcggc	Protospacer
 .**.*.******************

10. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggtggcccgacgccggcggcgcg	Protospacer
***********.*** *******  

11. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to AP021851 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-2 DNA, complete genome) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
ccggtggcgcggcccaggcggcggg	Protospacer
 ******* **** ********** 

12. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP048428 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
ctggtggtccggcgctggcggcggc	Protospacer
 .*****.******* *********

13. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to MN813693 (Mycobacterium phage Imvubu, complete genome) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggtggcccggcgcaggcaccgag	Protospacer
*******************. **. 

14. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP021407 (Celeribacter manganoxidans strain DY25 plasmid pDY25-C, complete sequence) position: , mismatch: 4, identity: 0.84

----gcggtggcccggcgcaggcggcggc	CRISPR spacer
tatcgc----gcccggcgcaggcggcggc	Protospacer
    **    *******************

15. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP053905 (Hymenobacter sp. BRD67 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggtggcccagcgcaggcgggccc	Protospacer
**********.**********   *

16. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
ccaggcgcccggcgcaggcggcggc	Protospacer
 *.*  *******************

17. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggtggccgggcgcaggcggggcg	Protospacer
********* *********** *  

18. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
ccggtgggccggcgcaagcggcggt	Protospacer
 ****** ********.*******.

19. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 4, identity: 0.84

gcggtggcccggcgcaggcggcggc	CRISPR spacer
gcggttgcccggcgaaggcggcgaa	Protospacer
***** ******** ********. 

20. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 5, identity: 0.8

gcggtggcccggcgcaggcggcggc	CRISPR spacer
cgggtggcgcggcgcaggcggcgca	Protospacer
  ****** **************  

21. spacer 3.1|853335|25|NC_013172|CRISPRCasFinder matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.8

gcggtggcccggcgcaggcggcggc	CRISPR spacer
cgggtggcgcggcgcaggcggcgca	Protospacer
  ****** **************  

22. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to MN284895 (Mycobacterium phage Marshawn, complete genome) position: , mismatch: 5, identity: 0.839

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtcgcgccgggaggaccggccgggccgggtc	Protospacer
*.**************** *** ******  

23. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_CP015097 (Pelagibaca abyssi strain JLT2014 plasmid pPABY7, complete sequence) position: , mismatch: 6, identity: 0.806

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gccgcgccgagaggcccgcccgcgccagccg	Protospacer
*********.**** ***********.*  .

24. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to JN698993 (Mycobacterium phage Firecracker, complete genome) position: , mismatch: 6, identity: 0.806

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gccgcgccgccaggaccgcccgcgccaccag	Protospacer
*********  ***************.  *.

25. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to KT281796 (Mycobacterium phage Zakhe101, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gccgcgccgccaggaccgcccgcgccaccgg	Protospacer
*********  ***************.  ..

26. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to MN428058 (Mycobacterium phage Krili, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gccgcgccgccaggaccgcccgcgccaccgg	Protospacer
*********  ***************.  ..

27. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to MH590592 (Mycobacterium phage Ryadel, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gccgcgccgccaggaccgcccgcgccaccgg	Protospacer
*********  ***************.  ..

28. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to MT818425 (Mycobacterium phage NiebruSaylor, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gccgcgccgccaggaccgcccgcgccaccgg	Protospacer
*********  ***************.  ..

29. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NC_022325 (Mycobacterium phage Dylan, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gccgcgccgccaggaccgcccgcgccaccgg	Protospacer
*********  ***************.  ..

30. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
ggtgcgccgcgaggaccgcccgcgccccgcc	Protospacer
* .****** ****************  *  

31. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to KJ944841 (Mycobacterium phage Cheetobro, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtcttgccgggaggaccggccgggccgggct	Protospacer
*.* .************* *** ******  

32. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to KY087992 (Mycobacterium phage Mitti, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtcttgccgggaggaccggccgggccgggct	Protospacer
*.* .************* *** ******  

33. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to MF140402 (Mycobacterium phage Chancellor, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtcttgccgggaggaccggccgggccgggct	Protospacer
*.* .************* *** ******  

34. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to MN693683 (Marine virus AFVG_250M978, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccg--cgccgggaa	CRISPR spacer
gccgcgccgggaggtccgcccggtggtccag--	Protospacer
************** *******   *.* .*  

35. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to KT361920 (Mycobacterium phage Slarp, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtcttgccgggaggaccggccgggccgggct	Protospacer
*.* .************* *** ******  

36. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to KX621007 (Mycobacterium phage Taquito, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtcttgccgggaggaccggccgggccgggct	Protospacer
*.* .************* *** ******  

37. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to MH051258 (Mycobacterium phage SamScheppers, complete genome) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtcttgccgggaggaccggccgggccgggct	Protospacer
*.* .************* *** ******  

38. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_CP035512 (Haematobacter massiliensis strain OT1 plasmid pOT1-2, complete sequence) position: , mismatch: 7, identity: 0.774

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gtggtgtcggaagaaccgcccgcgccgggat	Protospacer
*. *.*.***.**.**************** 

39. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP025513 (Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggtcacgcgtctgacccgtctcgccgggat	Protospacer
    .************ *.***********

40. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgccttgccgggat	Protospacer
    *.*********** ****.********

41. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgccttgccgggat	Protospacer
    *.*********** ****.********

42. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgtctcgccgggat	Protospacer
    *.*********** *.***********

43. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgtctcgccgggat	Protospacer
    *.*********** *.***********

44. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgtctcgccgggat	Protospacer
    *.*********** *.***********

45. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP030763 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgtctcgccgggat	Protospacer
    *.*********** *.***********

46. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP048424 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgtctcgccgggat	Protospacer
    *.*********** *.***********

47. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gggttgcgcgtctgacccgtctcgccgggat	Protospacer
    *.*********** *.***********

48. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to AP009146 (Sodalis phage phiSG1 DNA, complete genome) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
ccaacatgcgtctgaccggcatcgcctggac	Protospacer
** ..*.************* ***** ***.

49. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to DQ785801 (Sodalis phage phiSG1, complete genome) position: , mismatch: 7, identity: 0.774

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
ccaacatgcgtctgaccggcatcgcctggac	Protospacer
** ..*.************* ***** ***.

50. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.742

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
gctcggccgagaggatcgcccgcgccggccc	Protospacer
**.  ****.*****.************   

51. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.742

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
tcaaccgcgtgaggaccgcccgagccgggag	Protospacer
 * .*  ** ************ *******.

52. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to KY092482 (Streptomyces phage Mojorita, complete genome) position: , mismatch: 8, identity: 0.742

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
cccgcgccgggaagcccgcccgcgacatcca	Protospacer
 ***********.* ********* *.   *

53. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to KY092480 (Streptomyces phage Picard, complete genome) position: , mismatch: 8, identity: 0.742

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
cccgcgccgggaagcccgcccgcgacatcca	Protospacer
 ***********.* ********* *.   *

54. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
tcaaccgcgtgaggaccgcccgagccgggag	Protospacer
 * .*  ** ************ *******.

55. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_CP010721 (Phaeobacter piscinae strain P18 plasmid pP18_f, complete sequence) position: , mismatch: 8, identity: 0.742

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
atcgcgccgtgacgaccgcccgcgcagatag	Protospacer
..******* ** ************ *. *.

56. spacer 5.5|1536212|31|NC_013172|CRISPRCasFinder matches to NZ_CP016354 (Prauserella marina strain DSM 45268 plasmid pPmarDSM45268, complete sequence) position: , mismatch: 9, identity: 0.71

gccgcgccgggaggaccgcccgcgccgggaa	CRISPR spacer
tacgcgccgggagtaccgcccgcggtcgccc	Protospacer
  *********** ********** . *   

57. spacer 5.6|1536266|31|NC_013172|CRISPRCasFinder matches to NZ_CP041206 (Rhizobium sp. NIBRBAC000502774 plasmid pMK-3, complete sequence) position: , mismatch: 10, identity: 0.677

cccgtacgcgtctgaccggcctcgccgggat	CRISPR spacer
gtcgtacgcatctgaccgacctcgctaccgg	Protospacer
 .*******.********.******..  .