CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_013519	Sebaldella termitidis ATCC 33386 plasmid pSTERM02, complete sequence	0 crisprs	NA	0	0
NC_013517	Sebaldella termitidis ATCC 33386, complete sequence	10 crisprs	csa3,cas6,DinG,DEDDh,WYL,cas3	7	9
NC_013518	Sebaldella termitidis ATCC 33386 plasmid pSTERM01, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_013517_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_2

31760-31990

Orphan

Consensus_repeat	Method
TTTCAATAGCCATTTTATAGTATTTTTCTGATAATTCAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_013517_2

>merge|NC_013517|2|31760-31990|CRISPRCasFinder
TTTCTATGGCAATTTTATAATATTTTTCTGCCGGTTCAAACTTATTTTGTGTTTCATAGAAATCCCCCAGATGTCTTGGTGCATAAAAATTTCCATTTTCAACAGCGAGTAAATAATATTTTTCAGCTAAATCCGGTTTATCCCATTCTTCGTAAAGAATAGCGAGGCTGCCATAAGCATAAGTGTAATTTTTTTCAATAGCAGTTTTATAATATTTTTCAGCTAAATCTA

>NC_013517|2|2|31760-31990|CRISPRCasFinder
TTTCTATGGCAATTTTATAATATTTTTCTGCCGGTTCAA	ACTTATTTTGTGTTTCATAGAAATCCCCCAGATGTCTTGGTGCATAAAAATTTCCAT
TTTCAACAGCGAGTAAATAATATTTTTCAGCTAAATCCG	GTTTATCCCATTCTTCGTAAAGAATAGCGAGGCTGCCATAAGCATAAGTGTAATTTT
TTTCAATAGCAGTTTTATAATATTTTTCAGCTAAATCTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012859508.1\|26656_27025_-\|DUF1934-family-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859517.1\|37511_38474_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|238958
NC_013517.1\|WP_012859523.1\|42176_42821_-\|class-II-aldolase/adducin-family-protein	unknown	unknown	gnl\|CDD\|235829
NC_013517.1\|WP_012859511.1\|27979_29845_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630
NC_013517.1\|WP_012859503.1\|20983_21382_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859521.1\|40486_40771_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NC_013517.1\|WP_012859510.1\|27445_27913_-\|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	unknown	unknown	gnl\|CDD\|376840
NC_013517.1\|WP_012859504.1\|21427_21961_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277336
NC_013517.1\|WP_012859505.1\|22106_23291_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349941
NC_013517.1\|WP_012859506.1\|23382_24918_-\|AbgT-family-transporter	unknown	unknown	gnl\|CDD\|225525
NC_013517.1\|WP_012859514.1\|33306_34998_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|273568
NC_013517.1\|WP_012859520.1\|39364_40123_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235506
NC_013517.1\|WP_012859509.1\|27030_27423_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859522.1\|40792_42157_-\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NC_013517.1\|WP_012859516.1\|36385_37369_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NC_013517.1\|WP_012859512.1\|29837_30521_-\|thymidylate-kinase	unknown	unknown	gnl\|CDD\|223203
NC_013517.1\|WP_012859519.1\|38982_39255_-\|PTS-lactose/cellobiose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NC_013517.1\|WP_012859518.1\|38490_38964_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859507.1\|25101_26586_-\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NC_013517.1\|WP_012859515.1\|35017_36346_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012859511.1\|27979_29845_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
NC_013517.1\|WP_012859517.1\|37511_38474_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl\|CDD\|238958	cd02000, TPP_E1_PDC_ADC_BCADC, Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).	2.63929e-142
NC_013517.1\|WP_012859523.1\|42176_42821_-\|class-II-aldolase/adducin-family-protein	gnl\|CDD\|235829	PRK06557, PRK06557, L-ribulose-5-phosphate 4-epimerase; Validated.	1.19428e-87
NC_013517.1\|WP_012859514.1\|33306_34998_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|273568	TIGR01350, Dihydrolipoyl_dehydrogenase, dihydrolipoamide dehydrogenase. This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.	2.44991e-171
NC_013517.1\|WP_012859521.1\|40486_40771_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	7.53005e-34
NC_013517.1\|WP_012859510.1\|27445_27913_-\|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	gnl\|CDD\|376840	pfam02590, SPOUT_MTase, Predicted SPOUT methyltransferase. This family of proteins are predicted to be SPOUT methyltransferases.	7.51313e-63
NC_013517.1\|WP_012859504.1\|21427_21961_-\|metallophosphoesterase	gnl\|CDD\|277336	cd07390, MPP_AQ1575, Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain. This family includes bacterial and archeal proteins homologous to AQ1575, an uncharacterized Aquifex aeolicus protein. AQ1575 may play an accessory role in DNA repair, based on the close proximity of its gene to Holliday junction resolvasome genes. The domain present in members of this family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	2.25587e-50
NC_013517.1\|WP_012859505.1\|22106_23291_-\|amidohydrolase	gnl\|CDD\|349941	cd08021, M20_Acy1_YhaA-like, M20 Peptidase aminoacylase 1 subfamily, includes Bacillus subtilis YhaA and Staphylococcus aureus amidohydrolase, SACOL0085. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases or hippurate hydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). This family includes Staphylococcus aureus amidohydrolase, SACOL0085, which contains two manganese ions in the active site, and forms a homotetramer with variations in interdomain orientation which possibly plays a role in the regulation of catalytic activity.	6.05579e-169
NC_013517.1\|WP_012859506.1\|23382_24918_-\|AbgT-family-transporter	gnl\|CDD\|225525	COG2978, AbgT, Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism].	0
NC_013517.1\|WP_012859520.1\|39364_40123_-\|SDR-family-oxidoreductase	gnl\|CDD\|235506	PRK05565, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	9.04571e-78
NC_013517.1\|WP_012859522.1\|40792_42157_-\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	4.58717e-152
NC_013517.1\|WP_012859516.1\|36385_37369_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NC_013517.1\|WP_012859512.1\|29837_30521_-\|thymidylate-kinase	gnl\|CDD\|223203	COG0125, Tmk, Thymidylate kinase [Nucleotide transport and metabolism].	9.02406e-41
NC_013517.1\|WP_012859519.1\|38982_39255_-\|PTS-lactose/cellobiose-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.95917e-13
NC_013517.1\|WP_012859507.1\|25101_26586_-\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NC_013517.1\|WP_012859515.1\|35017_36346_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	4.40239e-147

>NC_013517.1|WP_012859512.1|29837_30521_-|thymidylate-kinase
MGKLIIIEGSDGSGKETQTNLLYKKLKERNFNIKKISFPNYESPASEPLKMYLSGEFGKDVNDVNSFAASTFFAVDRYASYKQDWEKFYNNSGIVLSDRYTTSNMVHQASKIENEEDKQIFLKWLIDLEWNKLGLPTPDIVIFLDVSPELSQKLMSDRKNKITGEEKKDIHETNSEYLKNSYYNALNLAKQYGWTIVSCETDGVLKNIEEINEDIIKKLSEKGVLYE
>NC_013517.1|WP_012859511.1|27979_29845_-|DNA-mismatch-repair-endonuclease-MutL
MNKIKILDESVSNIIAAGEVVENPASMIKELLENSLDAGADSVKIEVFNGGKDVKISDNGSGMEKNDMMLSIERHATSKISTKDDIFNLMTYGFRGEALASISSVSKMTISTKTKESNVGYKLTAYAGSIRNVEEISRNNGTEIEIRDLFYNTPARKKFLRKESTEYNKIRDIVLKEALVNYDTAFTLIFDDKPSIKTSGKGIENTILELFGKNVLKNLKKFEHGYLGSVEILRSSKDYIFTYVNKRYVKSNTIERAVLDGYYTKLMKGKYPFAVIFLNTDPKEIDVNVHPSKKIVKFSNDKIIYTQIKSAMDDYFYLEERREWQPNIDLLKQNVNISAAEPEKIENLFSDETLKGENKQFFSLETLDNRDVETRIIDERPKKAIETLITEPEDSDFIRENIKTDYPSYKEESKENNVSESIQKSSEENIKKPEDYKIIGQIFNMYILVENKNQLEIYDQHIIHERILYEELKEKFYSKKLDFQNLIIPQKIELTSPDKNLVMENIEVFRDFGFDVDEFGENEIILRSVPAFDFRDSIKNVFMDLLADLKNDIEVKDLRERIIISMSCKGAIKAGQKLDPDEISSFIRRLHEIGKYTCPHGRPIIINIPKDDLDKMFGRKG
>NC_013517.1|WP_012859510.1|27445_27913_-|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH
MLKINVTAVGKIKDSYIKDGILEFKKRLQKFSNFSIIELQEESENRGIESAVNTESKRILESIEGKNYYNILLDLDGIAVSSPAMAQKIMEISNFNSKVNFIIGGSNGVNNDVRNAADFRLSFSKLTFPHQLMRLILIEQIYRWISINNNIKYHK
>NC_013517.1|WP_012859509.1|27030_27423_-|hypothetical-protein
MFSVGEDFEVMIDDVNEYFNCIANLTIKGKEYIIAENEEGTKRAFLCDSNDDEIIVLAEDEEEDILNIWEEDYYGADKDYMFWNEEFEEYDKPTKEDLEYDESEPDDIHEVDDLDESEEDLEDFIENLLD
>NC_013517.1|WP_012859508.1|26656_27025_-|DUF1934-family-protein
MYLLIKSEDQFGNKYEKSFISQKTLLDNGIIYSYSDDHGESKIFLYENHIEIYRKGQINTKQIFKPKEMTNFLYLTKEFKKNLFLNTNFLDISEKNIYLIYDVIDENEVINTIKLKIIELEP
>NC_013517.1|WP_012859507.1|25101_26586_-|lysine--tRNA-ligase
MSEQQINEKSIIGEKLKKVEELKALGIEPYGRKFDKKDDIEDILKFDETSDKTFKTAGRIVAFRRMGKNGFGHIQDLSGKIQYYVKKDTVGEENYEIYKKLGVGDFIGIEGTLFRTQTGELTLRASSFEVLSKNIRPLPEKFHGLTDVETRYRQRYVDLVMNNDVKETFITRFKILRFIRNFLENKGFLEVETPMLHPIAGGANAKPFITHHNALDMDFFLRIAPELYLKRLLVGGFEKVFEINRSFRNEGTSIKHNPEFTMLELYQAYADFEDIMNLTEELVSSLVEELFGTTKLTYQDTEIDFTRPWKRIKMKDAVKDATGFDLDSINSDEEALNLVKSMNIPLEKDKAYTKYGLLNLLFEEKVEATLMNPTFITEYPKEISPLSKNKKDSVDFVDRFEMFIYGREHANAFSELNDPVEQKERFDAQEKMKEAGDDEAHETDLDYIRALEYGMPPAGGLGIGIDRLTMLLTDSFSIRDVLLFPALKKEDFEL
>NC_013517.1|WP_012859506.1|23382_24918_-|AbgT-family-transporter
MKTKKLNFFERFLNFFENVGNKMPDPVTLSFILCILVIIISKFVATTGISAIHPKSGETLLAVDLLTKTGFQKIFTSIISNFQGFPPLGVVLVTMFGAGVAEKTGFMEELLKVTTVKIPKPLVTACILFIGILANAAGDAGFIILPPLAAIIFISLKRHPLVGMLAAYAGVAAGFAANIFISISDVLAATFTIPAAQILDKNYTGTVAMNFYFLFVSTFVLVITGVFVTEKIIAPRFEGVEYDYHDEKIKDALDEDTRKKALKYSLISLGIFSVIVILLCIGDNAFFRDPETGSLTSSSSILMKSIVLLVTLAFFIPGVVYGIIVKKIRTDKDLVHLMGQSMSDMGLYIVLAFASAQFLAFFNESNLASIFSIKGAEGLKNLGISGIPLMILFIILSSVINLFIGSASAKWAIMAPIFVPMFMLLGYNPALIQMAYRIGDSVTNPLSPLFPYFPILLAVARKYDKKAGLGTLISNMIPYSLFFGIVWTLLLILFIIFNIPLGPDAGIHYSF
>NC_013517.1|WP_012859505.1|22106_23291_-|amidohydrolase
MTDRIKKLAEKYSSVIMGAREYFHANPGIEFQEFETTKKIIEILEEHGIEYQKDIAVTGILAIVRGKKEGKTVLLRGDMDALPIEEESDVPYKSKVKGVMHACGHDSHAAGLLGAALILNELKDEITGNIKFAFQPAEENQGGAKPMIDAGILENPKVDAAFGLHVWGPYPEGKALTMKGPMMAAPDNIRIKLIGKGGHASMPNMLIDPVVMAAEVILSLQTIVSRKVDPLEPAVISCCSIHGGSAQNVIPNEVEITGTVRTLNEEVRRKMPELMEQTIKGITDIYNGAYEFDYHFGFPCLVNDAKSTETLISAAGKILGNENVDIMAKPVMGGEDFAYFTQEVPSAFIFLGVAEDMENPPVHHHPKFAFHSKNTVTSSEILTQAALDFLENSK
>NC_013517.1|WP_012859504.1|21427_21961_-|metallophosphoesterase
MIYFTADTHFFHSNIINLCDRPFKNVDEMNKVLIRNWNSYITELDEIYILGDFLFKGTGSQANAILNTLKGKKYLIRGNHDKFLNDENFDMSAFEWVKDYFVLNYKKMKFVLFHYPILEWDGFFKDSVHLYGHVHNSGKDPGQNKRLSVLENKAFNVGVDVNNFFPVSIETIIKKQQ
>NC_013517.1|WP_012859503.1|20983_21382_+|hypothetical-protein
MRKTIILLLALMSFFSFSKNYEKAEDKKEGVSSIYLILKEGKGNSYDFFFEYVIDTGSLLPKLRQAAGTAYKNGNKYVCKDLRGEQITFDIRKDQVVISGSDYLEGVYNYLSESAKEDYETVEWALEEEKGY
>NC_013517.1|WP_012859514.1|33306_34998_-|dihydrolipoyl-dehydrogenase
MSVEIIMPKAGMSMEEGTIIKWLKEEGEAIKEGEPIVEILTDKVNMEVEAESSGYLLKKVRFENEVLPVFTVIGYIGEKGESVSEVKEAEKKEEVKTETKTSDEKEYDVIVIGGGPAGYISANKASQLGAKTALVEKRELGGTCLNRGCIPTKTYIKNIEILEEAEKAESRGLDIKVTKNISDLTKAVEFKNKVTKKLSQGVGGLLRSYGVDVYSTAGKLGEGKKVTLEDGQVLKGKKIILAGGSKTRYLNIPGIDSDKILTSTTILDLNKVPERLVIVGGGVIGCEFAEIFRGYGTEVTIVEAMSNLLPFNDKEISQELEKIFKKKGIKLLTDKQVTGFKDKGKEIETVLKSGESLSSDYVLFSIGREADLSCVDGLEIKQDRGRLIVNEYMETSIAGVYAAGDINGLSMLAHSAFKMGETAAGNALGGREEVRLDNTPKCVYTLPEIASVGLTEEEALKKYGKIRTGRFNFGANGRAIASSEEEGFVKVICDDNYGEILGVHVIGSKATEMISAGVILMEMEITIEEASELIYAHPTFSEAILEACADCLGKALHLPKKKM
>NC_013517.1|WP_012859515.1|35017_36346_-|2-oxo-acid-dehydrogenase-subunit-E2
MSVEIIMPKAGMSMEEGTIVKWLKSEGDEIKEGEPIVEILTDKVNMEVEAESSGFLIKKVRFEDEVLPVFTVIGYIGEKGETVSEREEKAKTAEVIKDEKKPDKKETEENSVFFNKSLMQSDKLNRATPAARKKARDNNLNLGDIPGSGPKGRVQLADVESFAAGSTVKATPLARKIAGQEGIDLDGISGTGAKGKIFKRDLVLNAAPEIISKEAELKPYSGIRKVIGDRMTESQFSAPTFTLNIEVGVNKLLKLKDKIAAPLMDETGEKLTINDLLILAVSRGVRKYPDINVSLTDKGILCHKEINVGFAVSGNGVLMVPVVKNTEDKGIRNILTEGKDLIKKAREGKLGAAEQSGSTITLSNLGMYGVHYFNPIINQPNSCIIGVGTIEEKPVAKAGKISVKKVIYLSATFDHRVIDGALGAEFMQYVKKLIEDPYSLLI
>NC_013517.1|WP_012859516.1|36385_37369_-|alpha-ketoacid-dehydrogenase-subunit-beta
MREITYAEAIREAMSEEMRRDENVYLLGEDVGIYGGAFGVSVGMIDEFGEERVRDTPISEAVIAGAAAGSAVTGMRPIAELMFMDFSTIAMDAIVNQAAKMRYMFGGKAQVPFVLRCPAGSGTGAAAQHSQSLEAWFCHIPGLKVVAPSTPYDVKGLLKSSIRDNNPVIFVEQKLLYRTKGEVPEEEYTIPLGVADIKRTGKDVTVVTYGRMLPRVLEAAEEAAKDGIDVEVIDPRTLVPLDIETIKNSVIKTGRLIVVNEAVKRGSYAGEIVSEVVESEAFDYLDSEIIRLSGKNTPIPYNPKLEAYVVPSKEDITEAIYKAMNRK
>NC_013517.1|WP_012859517.1|37511_38474_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MSEKKDIYREMYKRMNEARAFEQKVSWFFSRGMVHGTTHLSMGEEASGVAPCMALEDGDLITSTHRGHSQVIGKGVDLNKMMAELLGKATGYCKGKGGSMHIADIDSGNLGANGVVGGGHGLSVGAALTQQMKKTGKIVLCFFGDGAANEGSFHEALNLASIWKLPVIFYCENNLYGMSMSMERHMNITNIADRASSYGIPGHIVDGNDAVGLYDKMLEIFKYVREGNGPVLVESKTYRWLGHSKSDANVYRTKEEIEDWKSKDPIERMKKYLVSEKIFKEAELTAIEEQAKADIEKAVEFANNSPDPELETALTDVYAD
>NC_013517.1|WP_012859518.1|38490_38964_-|hypothetical-protein
MTYKYNKKKYFITVTLTSIFIVFLLIYAVIKNIFNFNINIYTFIILASCYELFNIYIAGVKPLEIELDSHKLVLRGYHKEDVYEIKDLKYMMTKELANKRLYLRINKYSLLKGRYWLDTKSYENSENLYLNIMELERLICPNQLKYNHRSRRVKENR
>NC_013517.1|WP_012859519.1|38982_39255_-|PTS-lactose/cellobiose-transporter-subunit-IIB
MKKILVATGTSVNKMKFAVETIKNYCANKNVECEVKGVNIYEMKLEEENPDVLVVIGPSDIKTDIPIIMGTAFITKMGMDKTCDEILSHL
>NC_013517.1|WP_012859520.1|39364_40123_-|SDR-family-oxidoreductase
MLLKDKVCVITGGANGIGKGIALCMAKEGANVAILDLNDTEGEKTLNEIKSHNVKGLYINSDVTNPESLAEAQKKISSELGNTDVLVVNAGISFKHSFKEVSDEEWKKVIDINLSGSFYTIKAFIDSMLDKKENDRKSIIFISSGSAFTGGGGGVHYTASKSGQHGLMRALAKEYGKAGINVNAIAPRVIASHILDQLYPDEKSKQELIEQIPIRRIGYPEDIGNLACFLASEKSTYIHGQIILMDGGRTYQ
>NC_013517.1|WP_012859521.1|40486_40771_-|PTS-sugar-transporter-subunit-IIB
MGKKKIMVACGTGIATSTVVVNKMSTLLKERGVDVDIQQCKVAELPYKTDNVDLIVTTTAYTSKKDIPVIVAVSFLTGIGVDKDLDKIIEILNK
>NC_013517.1|WP_012859522.1|40792_42157_-|PTS-galactitol-transporter-subunit-IIC
MGIIQSLVDFILGLGPSTMLPIILTIFGLILGQGLAKSFRAGVTVGVGFVGVNLVIGLLTSSLGKAAEALVTSLGLNFDIIDVGWPIGAAITFATPIAALLIPIIFILNMILLYFNITKTMDVDLWNYWHLIFPGAMVYYATNSLILAIVLTLINATIIFKLADWTAPAVEHHFGLPGISLPHGETVNFAPIMYALNKVEDKIPGINKINLDGEKLKEKIGIFGEPLILGIILGVLLGILGRYTVTDILSLGIQMGAVMVLMPKMVALLMEGLTPISEGAKDFISKRFPGKDVYIGLDAAVVIGNPSNMTVALLMVPITIFLSVILPYNRMLPFADLAVLPFTVIWAVAASRGDIFRGLINSIITLCMVFFMATNLGPLTTQMGHAVGFEFPAGATMISGIDMSCHITLWIILKLIDYKNTPMFIAGIVALVAYAGMWYWTRNDIKKQYENETE
>NC_013517.1|WP_012859523.1|42176_42821_-|class-II-aldolase/adducin-family-protein
MLEKLKLEVIDAGKKLKEYKLITLTGGNVSGRDLETGYIVMTPSGMEYDTLTPDDITVTDLDGNIIEGKRKPSSDLKTHLQIYRAKKDINGIIHTHSTFASCFAVLKEDIPVISTTMANEVGGKVPLSKYAPVGSDELGEHIIEKIGDQKAVLLESHGVFTYGENVSHALTAAVMLEDSAKVYYLTRTIGKPEELPEEEIKRANELFKNVYGQK

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Crispr_ID: NC_013517_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_1

31088-31607

Orphan

Consensus_repeat	Method
TTTCAATAGCCATTTTATAGTATTTTTCTGATAATTCAT	CRISPRCasFinder

5 spacers

The CRISPR arrays of NC_013517_1

>merge|NC_013517|1|31088-31607|CRISPRCasFinder
TTTCAACAGCGAGCAGATAATATTTTTCTGCCAGTTCTAATTTTTCTTCATTTTCATAAAGAAGTCCTAAACTGTTTATAGCATCATCATCTTTACAGTCAATAGCTATTTTGAAATATTTTTCCGCAAGATCATATTTATTCTGCCGTTCATAAAAATTAGCTAAATTTCCGGGTGCATAAGCATCATTTTTTTCAACAGCAAGCAAATAATATTTTTCTGCCAGTTCTGGTTTGTTATTATTATTATATAAAATTCCCAGGTCATTATAAGCATCAAAATTTTTTCTTTCAATAGACATTTTGAGATATTTTTCTGCTGAAGCAAATTTATTTTGTCCTGCATAAAGAGTTCCCAAATTTCTGGGAGCATAAAAATCATCTTTTTCAATAGCCATTTTATAGTATTTTTCTGATAATTCATTTTTTTTCCAGTTTTCATAAAGCAGACCCAGATCATTTAGAGCATCGGTATTATCTCTTTCAATAGCCATTTTATAATATTTTTCTGATAATTCATA

>NC_013517|1|1|31088-31607|CRISPRCasFinder
TTTCAACAGCGAGCAGATAATATTTTTCTGCCAGTTCTA	ATTTTTCTTCATTTTCATAAAGAAGTCCTAAACTGTTTATAGCATCATCATCTTTAC
AGTCAATAGCTATTTTGAAATATTTTTCCGCAAGATCAT	ATTTATTCTGCCGTTCATAAAAATTAGCTAAATTTCCGGGTGCATAAGCATCATTTT
TTTCAACAGCAAGCAAATAATATTTTTCTGCCAGTTCTG	GTTTGTTATTATTATTATATAAAATTCCCAGGTCATTATAAGCATCAAAATTTTTTC
TTTCAATAGACATTTTGAGATATTTTTCTGCTGAAGCAA	ATTTATTTTGTCCTGCATAAAGAGTTCCCAAATTTCTGGGAGCATAAAAATCATCTT
TTTCAATAGCCATTTTATAGTATTTTTCTGATAATTCAT	TTTTTTTCCAGTTTTCATAAAGCAGACCCAGATCATTTAGAGCATCGGTATTATCTC
TTTCAATAGCCATTTTATAATATTTTTCTGATAATTCATA

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012859508.1\|26656_27025_-\|DUF1934-family-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859517.1\|37511_38474_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|238958
NC_013517.1\|WP_012859523.1\|42176_42821_-\|class-II-aldolase/adducin-family-protein	unknown	unknown	gnl\|CDD\|235829
NC_013517.1\|WP_012859511.1\|27979_29845_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630
NC_013517.1\|WP_012859503.1\|20983_21382_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859521.1\|40486_40771_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NC_013517.1\|WP_012859510.1\|27445_27913_-\|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	unknown	unknown	gnl\|CDD\|376840
NC_013517.1\|WP_012859504.1\|21427_21961_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277336
NC_013517.1\|WP_012859505.1\|22106_23291_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349941
NC_013517.1\|WP_012859506.1\|23382_24918_-\|AbgT-family-transporter	unknown	unknown	gnl\|CDD\|225525
NC_013517.1\|WP_012859514.1\|33306_34998_-\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|273568
NC_013517.1\|WP_012859520.1\|39364_40123_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235506
NC_013517.1\|WP_012859509.1\|27030_27423_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859522.1\|40792_42157_-\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NC_013517.1\|WP_012859516.1\|36385_37369_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NC_013517.1\|WP_012859512.1\|29837_30521_-\|thymidylate-kinase	unknown	unknown	gnl\|CDD\|223203
NC_013517.1\|WP_012859519.1\|38982_39255_-\|PTS-lactose/cellobiose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NC_013517.1\|WP_012859518.1\|38490_38964_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012859507.1\|25101_26586_-\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NC_013517.1\|WP_012859515.1\|35017_36346_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012859511.1\|27979_29845_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0
NC_013517.1\|WP_012859517.1\|37511_38474_-\|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl\|CDD\|238958	cd02000, TPP_E1_PDC_ADC_BCADC, Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain alpha-keto acid dehydrogenase/2-oxoisovalerate dehydrogenase complex (BCADC). PDC catalyzes the irreversible oxidative decarboxylation of pyruvate to produce acetyl-CoA in the bridging step between glycolysis and the citric acid cycle. ADC participates in the breakdown of acetoin while BCADC participates in the breakdown of branched chain amino acids. BCADC catalyzes the oxidative decarboxylation of 4-methyl-2-oxopentanoate, 3-methyl-2-oxopentanoate and 3-methyl-2-oxobutanoate (branched chain 2-oxo acids derived from the transamination of leucine, valine and isoleucine).	2.63929e-142
NC_013517.1\|WP_012859523.1\|42176_42821_-\|class-II-aldolase/adducin-family-protein	gnl\|CDD\|235829	PRK06557, PRK06557, L-ribulose-5-phosphate 4-epimerase; Validated.	1.19428e-87
NC_013517.1\|WP_012859514.1\|33306_34998_-\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|273568	TIGR01350, Dihydrolipoyl_dehydrogenase, dihydrolipoamide dehydrogenase. This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.	2.44991e-171
NC_013517.1\|WP_012859521.1\|40486_40771_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	7.53005e-34
NC_013517.1\|WP_012859510.1\|27445_27913_-\|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	gnl\|CDD\|376840	pfam02590, SPOUT_MTase, Predicted SPOUT methyltransferase. This family of proteins are predicted to be SPOUT methyltransferases.	7.51313e-63
NC_013517.1\|WP_012859504.1\|21427_21961_-\|metallophosphoesterase	gnl\|CDD\|277336	cd07390, MPP_AQ1575, Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain. This family includes bacterial and archeal proteins homologous to AQ1575, an uncharacterized Aquifex aeolicus protein. AQ1575 may play an accessory role in DNA repair, based on the close proximity of its gene to Holliday junction resolvasome genes. The domain present in members of this family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	2.25587e-50
NC_013517.1\|WP_012859505.1\|22106_23291_-\|amidohydrolase	gnl\|CDD\|349941	cd08021, M20_Acy1_YhaA-like, M20 Peptidase aminoacylase 1 subfamily, includes Bacillus subtilis YhaA and Staphylococcus aureus amidohydrolase, SACOL0085. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases or hippurate hydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). This family includes Staphylococcus aureus amidohydrolase, SACOL0085, which contains two manganese ions in the active site, and forms a homotetramer with variations in interdomain orientation which possibly plays a role in the regulation of catalytic activity.	6.05579e-169
NC_013517.1\|WP_012859506.1\|23382_24918_-\|AbgT-family-transporter	gnl\|CDD\|225525	COG2978, AbgT, Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism].	0
NC_013517.1\|WP_012859520.1\|39364_40123_-\|SDR-family-oxidoreductase	gnl\|CDD\|235506	PRK05565, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	9.04571e-78
NC_013517.1\|WP_012859522.1\|40792_42157_-\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	4.58717e-152
NC_013517.1\|WP_012859516.1\|36385_37369_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NC_013517.1\|WP_012859512.1\|29837_30521_-\|thymidylate-kinase	gnl\|CDD\|223203	COG0125, Tmk, Thymidylate kinase [Nucleotide transport and metabolism].	9.02406e-41
NC_013517.1\|WP_012859519.1\|38982_39255_-\|PTS-lactose/cellobiose-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	2.95917e-13
NC_013517.1\|WP_012859507.1\|25101_26586_-\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NC_013517.1\|WP_012859515.1\|35017_36346_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	4.40239e-147

>NC_013517.1|WP_012859512.1|29837_30521_-|thymidylate-kinase
MGKLIIIEGSDGSGKETQTNLLYKKLKERNFNIKKISFPNYESPASEPLKMYLSGEFGKDVNDVNSFAASTFFAVDRYASYKQDWEKFYNNSGIVLSDRYTTSNMVHQASKIENEEDKQIFLKWLIDLEWNKLGLPTPDIVIFLDVSPELSQKLMSDRKNKITGEEKKDIHETNSEYLKNSYYNALNLAKQYGWTIVSCETDGVLKNIEEINEDIIKKLSEKGVLYE
>NC_013517.1|WP_012859511.1|27979_29845_-|DNA-mismatch-repair-endonuclease-MutL
MNKIKILDESVSNIIAAGEVVENPASMIKELLENSLDAGADSVKIEVFNGGKDVKISDNGSGMEKNDMMLSIERHATSKISTKDDIFNLMTYGFRGEALASISSVSKMTISTKTKESNVGYKLTAYAGSIRNVEEISRNNGTEIEIRDLFYNTPARKKFLRKESTEYNKIRDIVLKEALVNYDTAFTLIFDDKPSIKTSGKGIENTILELFGKNVLKNLKKFEHGYLGSVEILRSSKDYIFTYVNKRYVKSNTIERAVLDGYYTKLMKGKYPFAVIFLNTDPKEIDVNVHPSKKIVKFSNDKIIYTQIKSAMDDYFYLEERREWQPNIDLLKQNVNISAAEPEKIENLFSDETLKGENKQFFSLETLDNRDVETRIIDERPKKAIETLITEPEDSDFIRENIKTDYPSYKEESKENNVSESIQKSSEENIKKPEDYKIIGQIFNMYILVENKNQLEIYDQHIIHERILYEELKEKFYSKKLDFQNLIIPQKIELTSPDKNLVMENIEVFRDFGFDVDEFGENEIILRSVPAFDFRDSIKNVFMDLLADLKNDIEVKDLRERIIISMSCKGAIKAGQKLDPDEISSFIRRLHEIGKYTCPHGRPIIINIPKDDLDKMFGRKG
>NC_013517.1|WP_012859510.1|27445_27913_-|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH
MLKINVTAVGKIKDSYIKDGILEFKKRLQKFSNFSIIELQEESENRGIESAVNTESKRILESIEGKNYYNILLDLDGIAVSSPAMAQKIMEISNFNSKVNFIIGGSNGVNNDVRNAADFRLSFSKLTFPHQLMRLILIEQIYRWISINNNIKYHK
>NC_013517.1|WP_012859509.1|27030_27423_-|hypothetical-protein
MFSVGEDFEVMIDDVNEYFNCIANLTIKGKEYIIAENEEGTKRAFLCDSNDDEIIVLAEDEEEDILNIWEEDYYGADKDYMFWNEEFEEYDKPTKEDLEYDESEPDDIHEVDDLDESEEDLEDFIENLLD
>NC_013517.1|WP_012859508.1|26656_27025_-|DUF1934-family-protein
MYLLIKSEDQFGNKYEKSFISQKTLLDNGIIYSYSDDHGESKIFLYENHIEIYRKGQINTKQIFKPKEMTNFLYLTKEFKKNLFLNTNFLDISEKNIYLIYDVIDENEVINTIKLKIIELEP
>NC_013517.1|WP_012859507.1|25101_26586_-|lysine--tRNA-ligase
MSEQQINEKSIIGEKLKKVEELKALGIEPYGRKFDKKDDIEDILKFDETSDKTFKTAGRIVAFRRMGKNGFGHIQDLSGKIQYYVKKDTVGEENYEIYKKLGVGDFIGIEGTLFRTQTGELTLRASSFEVLSKNIRPLPEKFHGLTDVETRYRQRYVDLVMNNDVKETFITRFKILRFIRNFLENKGFLEVETPMLHPIAGGANAKPFITHHNALDMDFFLRIAPELYLKRLLVGGFEKVFEINRSFRNEGTSIKHNPEFTMLELYQAYADFEDIMNLTEELVSSLVEELFGTTKLTYQDTEIDFTRPWKRIKMKDAVKDATGFDLDSINSDEEALNLVKSMNIPLEKDKAYTKYGLLNLLFEEKVEATLMNPTFITEYPKEISPLSKNKKDSVDFVDRFEMFIYGREHANAFSELNDPVEQKERFDAQEKMKEAGDDEAHETDLDYIRALEYGMPPAGGLGIGIDRLTMLLTDSFSIRDVLLFPALKKEDFEL
>NC_013517.1|WP_012859506.1|23382_24918_-|AbgT-family-transporter
MKTKKLNFFERFLNFFENVGNKMPDPVTLSFILCILVIIISKFVATTGISAIHPKSGETLLAVDLLTKTGFQKIFTSIISNFQGFPPLGVVLVTMFGAGVAEKTGFMEELLKVTTVKIPKPLVTACILFIGILANAAGDAGFIILPPLAAIIFISLKRHPLVGMLAAYAGVAAGFAANIFISISDVLAATFTIPAAQILDKNYTGTVAMNFYFLFVSTFVLVITGVFVTEKIIAPRFEGVEYDYHDEKIKDALDEDTRKKALKYSLISLGIFSVIVILLCIGDNAFFRDPETGSLTSSSSILMKSIVLLVTLAFFIPGVVYGIIVKKIRTDKDLVHLMGQSMSDMGLYIVLAFASAQFLAFFNESNLASIFSIKGAEGLKNLGISGIPLMILFIILSSVINLFIGSASAKWAIMAPIFVPMFMLLGYNPALIQMAYRIGDSVTNPLSPLFPYFPILLAVARKYDKKAGLGTLISNMIPYSLFFGIVWTLLLILFIIFNIPLGPDAGIHYSF
>NC_013517.1|WP_012859505.1|22106_23291_-|amidohydrolase
MTDRIKKLAEKYSSVIMGAREYFHANPGIEFQEFETTKKIIEILEEHGIEYQKDIAVTGILAIVRGKKEGKTVLLRGDMDALPIEEESDVPYKSKVKGVMHACGHDSHAAGLLGAALILNELKDEITGNIKFAFQPAEENQGGAKPMIDAGILENPKVDAAFGLHVWGPYPEGKALTMKGPMMAAPDNIRIKLIGKGGHASMPNMLIDPVVMAAEVILSLQTIVSRKVDPLEPAVISCCSIHGGSAQNVIPNEVEITGTVRTLNEEVRRKMPELMEQTIKGITDIYNGAYEFDYHFGFPCLVNDAKSTETLISAAGKILGNENVDIMAKPVMGGEDFAYFTQEVPSAFIFLGVAEDMENPPVHHHPKFAFHSKNTVTSSEILTQAALDFLENSK
>NC_013517.1|WP_012859504.1|21427_21961_-|metallophosphoesterase
MIYFTADTHFFHSNIINLCDRPFKNVDEMNKVLIRNWNSYITELDEIYILGDFLFKGTGSQANAILNTLKGKKYLIRGNHDKFLNDENFDMSAFEWVKDYFVLNYKKMKFVLFHYPILEWDGFFKDSVHLYGHVHNSGKDPGQNKRLSVLENKAFNVGVDVNNFFPVSIETIIKKQQ
>NC_013517.1|WP_012859503.1|20983_21382_+|hypothetical-protein
MRKTIILLLALMSFFSFSKNYEKAEDKKEGVSSIYLILKEGKGNSYDFFFEYVIDTGSLLPKLRQAAGTAYKNGNKYVCKDLRGEQITFDIRKDQVVISGSDYLEGVYNYLSESAKEDYETVEWALEEEKGY
>NC_013517.1|WP_012859514.1|33306_34998_-|dihydrolipoyl-dehydrogenase
MSVEIIMPKAGMSMEEGTIIKWLKEEGEAIKEGEPIVEILTDKVNMEVEAESSGYLLKKVRFENEVLPVFTVIGYIGEKGESVSEVKEAEKKEEVKTETKTSDEKEYDVIVIGGGPAGYISANKASQLGAKTALVEKRELGGTCLNRGCIPTKTYIKNIEILEEAEKAESRGLDIKVTKNISDLTKAVEFKNKVTKKLSQGVGGLLRSYGVDVYSTAGKLGEGKKVTLEDGQVLKGKKIILAGGSKTRYLNIPGIDSDKILTSTTILDLNKVPERLVIVGGGVIGCEFAEIFRGYGTEVTIVEAMSNLLPFNDKEISQELEKIFKKKGIKLLTDKQVTGFKDKGKEIETVLKSGESLSSDYVLFSIGREADLSCVDGLEIKQDRGRLIVNEYMETSIAGVYAAGDINGLSMLAHSAFKMGETAAGNALGGREEVRLDNTPKCVYTLPEIASVGLTEEEALKKYGKIRTGRFNFGANGRAIASSEEEGFVKVICDDNYGEILGVHVIGSKATEMISAGVILMEMEITIEEASELIYAHPTFSEAILEACADCLGKALHLPKKKM
>NC_013517.1|WP_012859515.1|35017_36346_-|2-oxo-acid-dehydrogenase-subunit-E2
MSVEIIMPKAGMSMEEGTIVKWLKSEGDEIKEGEPIVEILTDKVNMEVEAESSGFLIKKVRFEDEVLPVFTVIGYIGEKGETVSEREEKAKTAEVIKDEKKPDKKETEENSVFFNKSLMQSDKLNRATPAARKKARDNNLNLGDIPGSGPKGRVQLADVESFAAGSTVKATPLARKIAGQEGIDLDGISGTGAKGKIFKRDLVLNAAPEIISKEAELKPYSGIRKVIGDRMTESQFSAPTFTLNIEVGVNKLLKLKDKIAAPLMDETGEKLTINDLLILAVSRGVRKYPDINVSLTDKGILCHKEINVGFAVSGNGVLMVPVVKNTEDKGIRNILTEGKDLIKKAREGKLGAAEQSGSTITLSNLGMYGVHYFNPIINQPNSCIIGVGTIEEKPVAKAGKISVKKVIYLSATFDHRVIDGALGAEFMQYVKKLIEDPYSLLI
>NC_013517.1|WP_012859516.1|36385_37369_-|alpha-ketoacid-dehydrogenase-subunit-beta
MREITYAEAIREAMSEEMRRDENVYLLGEDVGIYGGAFGVSVGMIDEFGEERVRDTPISEAVIAGAAAGSAVTGMRPIAELMFMDFSTIAMDAIVNQAAKMRYMFGGKAQVPFVLRCPAGSGTGAAAQHSQSLEAWFCHIPGLKVVAPSTPYDVKGLLKSSIRDNNPVIFVEQKLLYRTKGEVPEEEYTIPLGVADIKRTGKDVTVVTYGRMLPRVLEAAEEAAKDGIDVEVIDPRTLVPLDIETIKNSVIKTGRLIVVNEAVKRGSYAGEIVSEVVESEAFDYLDSEIIRLSGKNTPIPYNPKLEAYVVPSKEDITEAIYKAMNRK
>NC_013517.1|WP_012859517.1|37511_38474_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MSEKKDIYREMYKRMNEARAFEQKVSWFFSRGMVHGTTHLSMGEEASGVAPCMALEDGDLITSTHRGHSQVIGKGVDLNKMMAELLGKATGYCKGKGGSMHIADIDSGNLGANGVVGGGHGLSVGAALTQQMKKTGKIVLCFFGDGAANEGSFHEALNLASIWKLPVIFYCENNLYGMSMSMERHMNITNIADRASSYGIPGHIVDGNDAVGLYDKMLEIFKYVREGNGPVLVESKTYRWLGHSKSDANVYRTKEEIEDWKSKDPIERMKKYLVSEKIFKEAELTAIEEQAKADIEKAVEFANNSPDPELETALTDVYAD
>NC_013517.1|WP_012859518.1|38490_38964_-|hypothetical-protein
MTYKYNKKKYFITVTLTSIFIVFLLIYAVIKNIFNFNINIYTFIILASCYELFNIYIAGVKPLEIELDSHKLVLRGYHKEDVYEIKDLKYMMTKELANKRLYLRINKYSLLKGRYWLDTKSYENSENLYLNIMELERLICPNQLKYNHRSRRVKENR
>NC_013517.1|WP_012859519.1|38982_39255_-|PTS-lactose/cellobiose-transporter-subunit-IIB
MKKILVATGTSVNKMKFAVETIKNYCANKNVECEVKGVNIYEMKLEEENPDVLVVIGPSDIKTDIPIIMGTAFITKMGMDKTCDEILSHL
>NC_013517.1|WP_012859520.1|39364_40123_-|SDR-family-oxidoreductase
MLLKDKVCVITGGANGIGKGIALCMAKEGANVAILDLNDTEGEKTLNEIKSHNVKGLYINSDVTNPESLAEAQKKISSELGNTDVLVVNAGISFKHSFKEVSDEEWKKVIDINLSGSFYTIKAFIDSMLDKKENDRKSIIFISSGSAFTGGGGGVHYTASKSGQHGLMRALAKEYGKAGINVNAIAPRVIASHILDQLYPDEKSKQELIEQIPIRRIGYPEDIGNLACFLASEKSTYIHGQIILMDGGRTYQ
>NC_013517.1|WP_012859521.1|40486_40771_-|PTS-sugar-transporter-subunit-IIB
MGKKKIMVACGTGIATSTVVVNKMSTLLKERGVDVDIQQCKVAELPYKTDNVDLIVTTTAYTSKKDIPVIVAVSFLTGIGVDKDLDKIIEILNK
>NC_013517.1|WP_012859522.1|40792_42157_-|PTS-galactitol-transporter-subunit-IIC
MGIIQSLVDFILGLGPSTMLPIILTIFGLILGQGLAKSFRAGVTVGVGFVGVNLVIGLLTSSLGKAAEALVTSLGLNFDIIDVGWPIGAAITFATPIAALLIPIIFILNMILLYFNITKTMDVDLWNYWHLIFPGAMVYYATNSLILAIVLTLINATIIFKLADWTAPAVEHHFGLPGISLPHGETVNFAPIMYALNKVEDKIPGINKINLDGEKLKEKIGIFGEPLILGIILGVLLGILGRYTVTDILSLGIQMGAVMVLMPKMVALLMEGLTPISEGAKDFISKRFPGKDVYIGLDAAVVIGNPSNMTVALLMVPITIFLSVILPYNRMLPFADLAVLPFTVIWAVAASRGDIFRGLINSIITLCMVFFMATNLGPLTTQMGHAVGFEFPAGATMISGIDMSCHITLWIILKLIDYKNTPMFIAGIVALVAYAGMWYWTRNDIKKQYENETE
>NC_013517.1|WP_012859523.1|42176_42821_-|class-II-aldolase/adducin-family-protein
MLEKLKLEVIDAGKKLKEYKLITLTGGNVSGRDLETGYIVMTPSGMEYDTLTPDDITVTDLDGNIIEGKRKPSSDLKTHLQIYRAKKDINGIIHTHSTFASCFAVLKEDIPVISTTMANEVGGKVPLSKYAPVGSDELGEHIIEKIGDQKAVLLESHGVFTYGENVSHALTAAVMLEDSAKVYYLTRTIGKPEELPEEEIKRANELFKNVYGQK

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Crispr_ID: NC_013517_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_3

787264-787437

Orphan

Consensus_repeat	Method
GCAATAGGAATGTACGGAAAAAAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_013517_3

>merge|NC_013517|3|787264-787437|CRISPRCasFinder
GCAATAGGAATGTACGGAAAAAATGTCACAGACGGAATTTCAGGTGTGGATAACTATGCAAACATAACAAGTACAGCCACAAATGCAATAGGAATGTACGGAGAAAATTCCGGAGTAAAAAATGCCGGAACTGTAGCAATGTCTCTTGCAGGTGTGGGTATATACGGAAAAAAC

>NC_013517|3|3|787264-787437|CRISPRCasFinder
GCAATAGGAATGTACGGAAAAAAT	GTCACAGACGGAATTTCAGGTGTGGATAACTATGCAAACATAACAAGTACAGCCACAAAT
GCAATAGGAATGTACGGAGAAAAT	TCCGGAGTAAAAAATGCCGGAACTGTAGCAATGTCTCTTGCA
GGTGTGGGTATATACGGAAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012860195.1\|791708_792245_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NC_013517.1\|WP_115388829.1\|797817_798417_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_013517.1\|WP_012860197.1\|797069_797744_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|223862
NC_013517.1\|WP_012860186.1\|774190_775150_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NC_013517.1\|WP_012860191.1\|790791_791037_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860182.1\|767363_768368_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380486
NC_013517.1\|WP_012860199.1\|798707_799874_+\|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl\|CDD\|234960
NC_013517.1\|WP_012860190.1\|790011_790392_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370466
NC_013517.1\|WP_049768966.1\|771514_773269_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225942
NC_013517.1\|WP_012860192.1\|791047_791191_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860194.1\|791514_791712_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860183.1\|768443_771518_-\|beta-galactosidase-subunit-alpha	unknown	unknown	gnl\|CDD\|236673
NC_013517.1\|WP_012860196.1\|793101_796872_+\|autotransporter-domain-containing-protein	unknown	unknown	gnl\|CDD\|377133
NC_013517.1\|WP_041310373.1\|773279_774110_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_013517.1\|WP_012860188.1\|776400_777270_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_013517.1\|WP_012860179.1\|764573_765182_-\|5-formyltetrahydrofolate-cyclo-ligase	unknown	unknown	gnl\|CDD\|274270
NC_013517.1\|WP_012860181.1\|766137_767280_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NC_013517.1\|WP_012860193.1\|791215_791494_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860187.1\|775162_776404_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270303
NC_013517.1\|WP_012860180.1\|765296_766079_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012860195.1\|791708_792245_+\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	6.72352e-36
NC_013517.1\|WP_115388829.1\|797817_798417_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.12911e-14
NC_013517.1\|WP_012860197.1\|797069_797744_+\|C40-family-peptidase	gnl\|CDD\|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	5.43173e-08
NC_013517.1\|WP_012860186.1\|774190_775150_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	9.50496e-87
NC_013517.1\|WP_012860182.1\|767363_768368_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380486	cd01544, PBP1_GalR, ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism. Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism. Transcription of the galactose regulon genes is regulated by Gal iso-repressor (GalS) and Gal repressor (GalR) in different ways, but both repressors recognize the same DNA binding site in the absence of D-galactose. GalR is a dimeric protein like GalS and is exclusively involved in the regulation of galactose permease, the low-affinity galactose transporter. GalS is involved in regulating expression of the high-affinity galactose transporter encoded by the mgl operon. GalS and GalR are members of the LacI-GalR family of transcription regulators and both contain the type 1 periplasmic binding protein-like fold. Hence, they are structurally homologous to the periplasmic sugar binding of ABC-type transport systems.	9.33358e-114
NC_013517.1\|WP_012860190.1\|790011_790392_+\|hypothetical-protein	gnl\|CDD\|370466	pfam09403, FadA, Adhesion protein FadA. FadA (Fusobacterium adhesin A) is an adhesin which forms two alpha helices.	2.70094e-16
NC_013517.1\|WP_049768966.1\|771514_773269_-\|hypothetical-protein	gnl\|CDD\|225942	COG3408, GDB1, Glycogen debranching enzyme [Carbohydrate transport and metabolism].	4.12839e-21
NC_013517.1\|WP_012860183.1\|768443_771518_-\|beta-galactosidase-subunit-alpha	gnl\|CDD\|236673	PRK10340, ebgA, cryptic beta-D-galactosidase subunit alpha; Reviewed.	0
NC_013517.1\|WP_012860196.1\|793101_796872_+\|autotransporter-domain-containing-protein	gnl\|CDD\|377133	pfam03797, Autotransporter, Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.	1.88596e-29
NC_013517.1\|WP_041310373.1\|773279_774110_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.28911e-90
NC_013517.1\|WP_012860188.1\|776400_777270_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	1.02722e-12
NC_013517.1\|WP_012860179.1\|764573_765182_-\|5-formyltetrahydrofolate-cyclo-ligase	gnl\|CDD\|274270	TIGR02727, Uncharacterized_protein_YqgN, 5,10-methenyltetrahydrofolate synthetase. This enzyme, 5,10-methenyltetrahydrofolate synthetase, is also called 5-formyltetrahydrofolate cycloligase. Function of bacterial proteins in this family was inferred originally from the known activity of eukaryotic homologs. Recently, activity was shown explicitly for the member from Mycoplasma pneumonia. Members of this family from alpha- and gamma-proteobacteria, designated ygfA, are often found in an operon with 6S structural RNA, and show a similar pattern of high expression during stationary phase. The function may be to deplete folate to slow 1-carbon biosynthetic metabolism. [Central intermediary metabolism, One-carbon metabolism].	5.38773e-38
NC_013517.1\|WP_012860181.1\|766137_767280_+\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	5.81963e-157
NC_013517.1\|WP_012860199.1\|798707_799874_+\|tRNA-4-thiouridine(8)-synthase-ThiI	gnl\|CDD\|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	6.03433e-178
NC_013517.1\|WP_012860187.1\|775162_776404_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.89217e-85

>NC_013517.1|WP_012860188.1|776400_777270_-|DMT-family-transporter
MLLLVAVIWGTGFTASKIAVESGVLPFWMMTLRFGIAGIALLFLIIYHKSKITKKEIKAGIITGIFLYAAFATQTIGIQYTTSAKNAFLTGTNVIFVPYLCWIIFRKKPDKFALFSTLLAFFGICLLSVDTNELGSLSMNKGDIYTLFCALFFALHIIALDYFTKIYDTLILAFLQIIFAFLFSAVSALITGQVSFGISSQGLLATLYLGIFSTFLAFTIQTAAQKYTSSAKTVVILSTETVFGAVFSILILNEQFTTKLLIGCLFIFAAIIISETKLNFIYKSRRNII
>NC_013517.1|WP_012860187.1|775162_776404_-|sugar-ABC-transporter-substrate-binding-protein
MKKIFIINLLLLLLLISCGGGSKKNEAADGTVTLRFATWDSGEALNIQKEIAKKFEEKNPNIKVQVEAYGDGFDQKLVAAFGAKDAPDVMYMWDFPTYGSSLEDLNAYIEKDSSVDMKDFYEGLMNYVQLDGKTYGIPAGFTTHVIYFNKKLFDDANVPYPTEEWTWEEFAEKAQKLSRPEEKVYGFGVLAKPDPYDFEQFLWSFGSSYISPDGKTLKGYMDSPESAAAAQLFADLVKNKAGVLVGSKDQQSGDDIFKAQKIAMWESGIWPMNGFKSADIDFGVALLPRKGNNSPKSVMSVSAVSMWKGSKHKDAAWEFIKFYNSEEAAKLRVADLPVRKSLVEKFEILNDPMMAPFYKMLETSDNTPAFLLNKNWKEVQRNLAMALENILIGNTDAKTGLADVVNKSEHLLN
>NC_013517.1|WP_012860186.1|774190_775150_-|sugar-ABC-transporter-permease
MNTVISKKTKKFNLTPYLFISPWIIGFLLFTLGPLIFSLVISFFNWPIVGDAEFVGIKNYQTMLTKDPQFWASLGITLKFSFLFVPLNIITALILAILLNQNVKGSGIFKTIFYLPSVISGVALAMIWSWVYSGEYGILNYFLSLIHIQGPNWLLDSKWAVISMVLASLWGQGTMMLIFLTGLKNIPKELYEAAEVDGANPVQKFFKITLPMLSPTILFNVITSIINAFQQLTLALLLTGGGPAGATYFYAMYVYDNAFKYFKMGYSSANAWFMFIIILLLTLLVFKSSSMWVYYEGEVSKTKKTKKKFGFLKKSFQKA
>NC_013517.1|WP_041310373.1|773279_774110_-|carbohydrate-ABC-transporter-permease
MKTNKLLKNIFIYALLIFCSLLFLAPFYWMFSTSVKPSNEVFLFPPKWIPSHFKFENFGNAWQLQPFGMFLKNSLIVVGMTTVAQVFSSSLIAYGFARFDFKGKNFLFIIVLATMMIPWDVTMIPLYMEFNLFGWINTLKPLIVPSFFGSGFFIFMLRQFLLGIPKELDEAARIDGANAFQIYWRIYLPLMKPALILVAIFNILNTWNDYLGPLIFLNDQSKYTLTLGLAQFKGVFGVDTTAIMAITTLICIPPVLIFFIAQKHIVEGVSSTGLKG
>NC_013517.1|WP_049768966.1|771514_773269_-|hypothetical-protein
MQNFQAIEINKNCIERKKMKINIENISFSRYGSFLSVSYYKEEKELGKGLYIRNIRGGDEDSGDFLLAEMLEDGVLVNYGIDMEPERLKLTGKKGEIELIISEKNEIRIRGKNCSLRLTLNNQSYDHIISHENNNWEFNSYSKHIKSMFVPLSGKTVITAPWNEERSEKVQAEICGESFECVLHFYKSVYLPKEKYKDFDLSLEEIKKEFSAWLESFPVPVKYKEENALAAYVLWNNTVYSEGVLTHDAVYMSKNWMTNIWSWDNCFVAMALIENHPELAWAQLEAFYSLQDESGLFPDYINDRYASFSCCKPPVHGWAVKYMYEKNPEFFKDKLEMIYNMLSGWTNFWLTYRTHKNDPIPKYYHGNDSGWDNSTVFHDGGPLESPDLISFLILQMNYLSELAKELSLNDKTEFWKNKSNEFLKILINEFWNGEKFISKKIENNKKIPVTKGDSLISYIPLILGKLLPENISDKMISGLKEDGRFLTDYGLATESLKSPFYNSDGYWRGPIWAPVMMLMTDALYRTGEIEFSKELSARYLNLVHTGGLAENFDAKTGKGLRDKGFAWTSAVFLILNNSFERTNE
>NC_013517.1|WP_012860183.1|768443_771518_-|beta-galactosidase-subunit-alpha
MKIWENININNINRLKQRADFRLYDNINAAIDNRRKKNSKNLNGVWKFLFLDAPEYSPEGFFEKSFDTSDWDNITVPGNWQMQGYGKMHYSDLWYNFPINPPYVPSLNPTGIYKRTFSIPDSWKNERIILKFHGVDSAFHIYLNGKEIGYSKGARYEAEFDITDHIVRNSENDLTVRVYQWSDGTYLEDQDMWWLSGIFRDVEIYAEPFDCIDDIFVTTDLDENYTDSVLNVSVSFRGNVLGCTVNYLLLDDQDNEILNIENNLNSNFDNISEKIANPKKWSAETPYLYTFIITLKKEDQILAVAGQKTGFRKIEIKGNTFTVNNVAIKLKGVNRHDYNPANGRVVSREEMEKDIILMKQNNINAVRTAHYPNSSCFYDLCDEYGLYVIDEADLECHGFELTEKYDWITDDPVWKSAYIDRLERMMARDKNHPSIIMWSLGNESAFGDNFRAMAEYAKKNDPTRLVHYEGDFEAEVTDVFSTMYTWLEKNSQTPEVKKVFMKDIALTSKKPHILCEYAHAMGNGPGNFKEYQDLFYEYEHLQGGFVWEWFDHGIQAYDKNGNSYYKYGGDFGDNPNNGNFCIDGLLMPDRTPSPSLFEYKKIIEPVKTEAVDLNNGILKLTSRYDFINLNILTMSYSVYEDNRIIKSGSLALDISARDTKNICIEALKEIKYKDTHDYYLNISYRTNKRTNWSDEGHELAAAQFLLSEKTEFCNKKTDGSLLVSETQSVLNIYGLDFKCAFDKITGRMLYAEKDGLKILENGPELNFWRAPIDNDMYLLEDYYKKYFMNLMTENTESFLYNAADNYVEICVKTINGAPNAAWYYKSTYLYKVFADGTILFDIEGIPSGITAQAPEMIPRIGVKLRLNKACENVRWHGKGPGESYPDSKESQLFGFYENNIDGLFTNYVKPQENGSRSSCSWTRLLNDRGMGLMVYSQDKFDFSARFFEDSDLEYAGHTPDLKKRDYITLNIDYKQNGLGSNSCGQSQMEKYKCRFEKFSLSLKISLYNNKEINDLDLAGEKIIF
>NC_013517.1|WP_012860182.1|767363_768368_-|LacI-family-DNA-binding-transcriptional-regulator
MATIKDIAEKAHVSITTVSRVLNYDNTLKVTDKTRKKIFEIAEKLEYLKEKKPKNKKSSYSVNIIKGYSEQEELDDIYYLSTRLAIEKSLKQNNVKYEILEKDAISDSLKKLDGIILTGLFSQNEIDTVKKMNQNIIFSDIYIEDENIDCVIFDIRKSVRKVLDYLLNLGHKKIGFIGGSDVINGENTIDFRQIHYIEYMKEKKLYNESFIKIGAFTSDCGYKYMNEILDSSEYPSAFFLANDSIAIGAYKAVEEHKLSIPEDISIVGFNDISITQYMSPPLTTVKIYTDFMGETTVSLLMERIRDGRKLSKKVILPTELVIRKSCIEKNTVSK
>NC_013517.1|WP_012860181.1|766137_767280_+|cysteine-desulfurase
MIYLDNAASTRVREEVLETVNDILLNDYANPDAAHEFGLQAAKRIKKSRQIIADALSVSTKEVYFTSGGSEGNNIIIQGIINGNPRQGKHLITTKIEHPSIFEIFKEYERNGFEVTYLNVDSDGRIKLDELTDSIRDDTVLISVIAVNSETGVIQDLEKIGNIIKQKNKNVYFHSDFVQGLGHIKINPAKCRLDALTVSSHKVYGPKGAGAIYLSGNVKIKPLIFGSNQEQGVVQRTLNSSGIIGFGKAVQIACENFSKDNAQIKEVKEYLLQKIQNEISDIRVNTIEEDSVPHILNISFRGIQGEVLVHFLGMSKIYVSTGSACSSRKGNSRILESMGLTKEEVAGGIRFSFSVFNTKEEMDETVKVLKEAVAAIRMMK
>NC_013517.1|WP_012860180.1|765296_766079_+|hypothetical-protein
MSKFKKIIYILLIMVIYLILIFIQVTPKISFKGRVMGIPVNERVYIYPGKNISISKIDDRYTGIISPGVIELSPGTHEIKAEYKRDGIAGEYYFEPYNYPPGTKVIVTATEKKGARNGLEFDLKLGEEKAEGGLNILEYIFYTISTLIASVAVFVLTKQLKIVRKYERKARINEGAFLKTAEDLYLYKINGKRINIKSMKVPGGKYFFDIVYKKKNEKGFFAGTTSIQFDNVEIEVLDKDILEIGYLIENKKIRLDFKLV
>NC_013517.1|WP_012860179.1|764573_765182_-|5-formyltetrahydrofolate-cyclo-ligase
MAKTEIRDFNLNIRNRLHPNFVNHKSQIILNNLFCILNNDYYKNILIFMEIKNEVTISNVTKQYKNKNFFIPKTFKDGTMKINTLDTSKLVKNKFGILESSDTDYADPETLDLIIVPGVVFDQNLSRIGYGKGFYDNFLSSIKKSVLKVGVCYDFQLYDNIPTSKNDIKMDLIVTEKRTVISDHPKYSKTFLECYLPSTIPE
>NC_013517.1|WP_012860190.1|790011_790392_+|hypothetical-protein
MRKLLICFMICLSAGSYAYTRTSTITKEAEKIEKAEEQRKDRLSRRKDKLESELAELLKNYNSRVEITEKLKMDSEVRWYRDEYKEILKKYESVQDNLEKEIEKKERELAIVNRGLGISAEEITEE
>NC_013517.1|WP_012860191.1|790791_791037_+|hypothetical-protein
MKKVIILSALLIFSAGQVSLSAPKVRKVKKTESQKMKEEIDRIEKRVNEINKNIEDYKTAEIKLDELDEKYSQTMKDLRLE
>NC_013517.1|WP_012860192.1|791047_791191_+|hypothetical-protein
MKKIFLSAIALLIITACTSGETKRTIDDTKERVKNTEQYLWENQVVE
>NC_013517.1|WP_012860193.1|791215_791494_+|hypothetical-protein
MKRKVFIYGLLGFLLGIAGFAAEEEIYDIEEIQILEEEKIPLTKVEKAEQELAHMQGKVDFYKRVVRSVEREEAELKELNKIKMRDIKKTIK
>NC_013517.1|WP_012860194.1|791514_791712_+|hypothetical-protein
MKKIILLSVFFLTVSCSTNKALVEYNRQRMDKNEEYLNSVEGKTVPKGEINGTTRRVPLEKEADR
>NC_013517.1|WP_012860195.1|791708_792245_+|OmpA-family-protein
MKKLALVLLLAVLTVQGMARPFTTKQMRNDTIRINAMEVELINEKTEPAEKKEVKEEKKVIRLGEDKLYFDFDDSRVKPEYYGELRAAAEVIKNSSMRVNITGYTDSKGSAEYNEKLSLRRAEAVKAKLMEFGLNENYIAGVRGLGESNPIAPNTKSDGKDNPEGRAKNRRIELELIK
>NC_013517.1|WP_012860196.1|793101_796872_+|autotransporter-domain-containing-protein
MKKSFLKAGAFILALAPAISMGTQNSFGNPDEFLLWGSYYKFKNNKKSTYTSNFKETEGSEEEGEKPVPPVPVPDPIAVVKENGIIKAWKNNTGDSLYYTVSDNIFSADKAALWLTDLNTKVVNNKILDSVFTGAGSERFSVEAEGNAVFVNNGTVTGTHGGIRGKNGTVIYNNNIIANTGDYGMYQEDGDAYNNSAGVISNTGDYGIFAATENSNAVNEGIIDNSGNYGIAVNGGKAVNAASGVVKNGQDYGIWGYGVNSEVINNGTVENGGTHGIFLSDRSEGVNNGTVKNAGDYGVALSDSYFENTGIIENTGMHGVYADIGSQVLNNTTGVIQNNGDYGVTVSNTGAVASKALNKGTVKNNGNYGMFAEWNGAVIENEGMIENTGTHGMYAENGAEALNTVGGIVKNLGNTGMAASGSGAMVINNGTIENIGENGFHISASGEGINNGIIKNAGNYGMRVMNNSYVRNTGTIANNGTNGILVTVNSEALNDTTGIIENQGNYGIAVGSASKAENKGIIKNNGANGLYVINGGLGINSGTIENTGTHGIFITEAGSKGVNDGTIKNTGTHGMYATNDSEAVNGSGGIIENTGNYGIVAGKDSLGINNGIIRNQGTNGMYTTNAGTIINNGRIENVGTYGMQATAAGSQAVNGVSGVIANKGTSGLYAINGAHAVNKGRIENTGDYGMHLNNATGINEGTIHLTGDNKVGVHINNNAVFTNNGTIIVDGNNVTGIKAMGNSVVQIAQNSQIILNGNAAVTQSSTDYSDKQSTGAANSNSAGKAYNIDSTSTLINAGTISAYGTFTVEETGKFVLDTKTGVINAESINLEGDLHINAAGTADSFSNKFILENLNTGKLTGDGTLISDSFLFTGKLEKNSGGKYDIVMERKNFSEVFNSEFGKILESNYNESGNTEEKSKIYNSLKMSITSEAKALTAENELTGRSIVSNLMYQEFRRNRVLEAGVNDLLENRDRSADKGVYVNILGGKEDADNDGEFLGYKNREAGVIFGMMKKINGRISAGGFAGYLNSDIDYKDDGNSNQKTDTFSLKGALEAEITDSLKWRNVLGYNYGNTDTKRKLTYDRSYTELNGNFDSWSAEIDTNLEYTYNLNKSISVIPSAGLNVSYLHQNSYTESGADGYNLKVDSASGTSVRPKAGVRAELGLYENKNTKLKLVPSALYSYETANPYKIRNIGIGAFDDTLSLDSRDSERGNLDLGIGLEYNYNRELVFYGQYKKEVLNDSGDDKMSLGFKVYF
>NC_013517.1|WP_012860197.1|797069_797744_+|C40-family-peptidase
MKKVCIFLFLAVSIFGFSKKTYDETKFRQELIDWASSKVGAAYSMENRWGENTYDCSSFISRGLRETGMISVSGKKSDYGTTARGLYNNSGQKIEKDDYGLLKPGDIVHFSPVVSTTTGHVGIVIRNLGKGRVEIIDARGTIFGVVRRVTNLSKNKRYLGATSASQILRNNGYTPVNQEGIINIPKKSYHLSPVQSAGIFTGGIIIFFIMVKIFKKRKRRKIKG
>NC_013517.1|WP_115388829.1|797817_798417_-|TetR/AcrR-family-transcriptional-regulator
METKEKILLGMLDLVAETGLEKASIGRLCKKIKVSPGNVYFYFSSKVELLNTLYYYCINSLIEAVDIKTYTEISKDEECTVYTTLMEDLVKKVIYFYKSNPCMLNFIITSKSSCYLSDEIKRGRFTGANFFNSFWEKCKDKGIIKNVSTEFIIAFILGVIYEFMKEDIIHKNISLDDEKIDILNDLIWSGLYVENRVMS
>NC_013517.1|WP_012860199.1|798707_799874_+|tRNA-4-thiouridine(8)-synthase-ThiI
MYNALGISYGELALKGKNRGNFERILNTRIRNILKGTDYKLIIDSSKLYILSDQENIDEIIRKVKKIFGIVLISPSVRVDNDEDEIKKAVLEAAERAYENGARNFKVEVKRSNKKFQKRSMDFARELGGHILVNSKFEHVKMKNPDVMIYLEIRNSTYICTEKIKTYGGLPLGTTGKGLVLLSGGIDSPVAAFMMAKRGMFVNAVTFHSFPFTSTQALEKVKELTEILSLYIPKTRLFSMNILKIQQEINQKTNKELATILTRRVMMRLAEKLAKSRGYGALITGESLGQVASQTIGGLTCTNASVKDIPVFRPLIGMDKTEIMDIAAEIDTYEKSIEPYEDSCVIFAPKHPVTNPKLENVLLEEEKIEGYDEIMEEIYNNMEIFTFE

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Crispr_ID: NC_013517_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_4

1068878-1068972

Orphan

Consensus_repeat	Method
GGTACTATAAATATAACAGGTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013517_4

>merge|NC_013517|4|1068878-1068972|CRISPRCasFinder
GGTACTATAAATATAACAGGTAATGATGCAATAGGAATGTATGCTAATCCCGGAACAATAATAACAAATACAGGTACTATAAATATAACAGGAAA

>NC_013517|4|4|1068878-1068972|CRISPRCasFinder
GGTACTATAAATATAACAGGTAA	TGATGCAATAGGAATGTATGCTAATCCCGGAACAATAATAACAAATACA
GGTACTATAAATATAACAGGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012860456.1\|1083275_1083416_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860451.1\|1055853_1062867_+\|autotransporter-domain-containing-protein	unknown	unknown	gnl\|CDD\|377133
NC_013517.1\|WP_012860454.1\|1082614_1082989_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370466
NC_013517.1\|WP_012860447.1\|1044682_1051612_+\|autotransporter-domain-containing-protein	unknown	unknown	gnl\|CDD\|377133
NC_013517.1\|WP_012860453.1\|1071488_1082546_+\|autotransporter-associated-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|380182
NC_013517.1\|WP_012860461.1\|1085525_1086284_+\|DKNYY-domain-containing-protein	unknown	unknown	gnl\|CDD\|372659
NC_013517.1\|WP_041309814.1\|1043139_1043529_+\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NC_013517.1\|WP_012860449.1\|1052378_1053407_+\|tRNA-2-selenouridine(34)-synthase-MnmH	unknown	unknown	gnl\|CDD\|274463
NC_013517.1\|WP_012860448.1\|1051803_1052178_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319899
NC_013517.1\|WP_012860457.1\|1083432_1083657_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860441.1\|1039917_1041117_+\|2-dehydro-3-deoxy-6-phosphogalactonate-aldolase	unknown	unknown	gnl\|CDD\|239438
NC_013517.1\|WP_012860450.1\|1053647_1054565_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860459.1\|1083868_1084408_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NC_013517.1\|WP_012860455.1\|1083020_1083263_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860460.1\|1084689_1085430_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_013517.1\|WP_169305389.1\|1071102_1071255_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860443.1\|1042205_1042451_+\|DUF333-domain-containing-protein	unknown	unknown	gnl\|CDD\|377156
NC_013517.1\|WP_012860444.1\|1042784_1043000_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860458.1\|1083674_1083872_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860442.1\|1041189_1041903_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012860451.1\|1055853_1062867_+\|autotransporter-domain-containing-protein	gnl\|CDD\|377133	pfam03797, Autotransporter, Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.	1.0044e-19
NC_013517.1\|WP_012860454.1\|1082614_1082989_+\|hypothetical-protein	gnl\|CDD\|370466	pfam09403, FadA, Adhesion protein FadA. FadA (Fusobacterium adhesin A) is an adhesin which forms two alpha helices.	6.78977e-19
NC_013517.1\|WP_012860447.1\|1044682_1051612_+\|autotransporter-domain-containing-protein	gnl\|CDD\|377133	pfam03797, Autotransporter, Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.	8.04838e-22
NC_013517.1\|WP_012860453.1\|1071488_1082546_+\|autotransporter-associated-N-terminal-domain-containing-protein	gnl\|CDD\|380182	NF033175, fuso_auto_Nterm, autotransporter-associated N-terminal domain-containing protein. This domain typically is found in the genus Fusobacterium, in N-terminal regions of large proteins that are recognized as autotransporter proteins by C-terminal regions matching Pfam model PF03797. In paralogous families of such proteins, the N-terminal and C-terminal regions are fairly well-conserved, but the repetitive central region is poorly conserved in both length and sequence.	5.25036e-32
NC_013517.1\|WP_012860461.1\|1085525_1086284_+\|DKNYY-domain-containing-protein	gnl\|CDD\|372659	pfam13644, DKNYY, DKNYY family. This family represents a group of proteins found enriched in fusobacteria. These proteins contain many repeats of a DKNXXYY motif. The repeats are spaced at about 35 amino acid residues intervals. These proteins are likely to be associated with the membrane. The specific function of these proteins is unknown.	5.764e-17
NC_013517.1\|WP_041309814.1\|1043139_1043529_+\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	2.1791e-39
NC_013517.1\|WP_012860449.1\|1052378_1053407_+\|tRNA-2-selenouridine(34)-synthase-MnmH	gnl\|CDD\|274463	TIGR03167, tRNA_sel_U_synt, tRNA 2-selenouridine synthase. The Escherichia coli YbbB protein was shown to encode a selenophosphate-dependent tRNA 2-selenouridine synthase, essential for modification of some tRNAs to replace a sulfur atom with selenium. This enzyme works with SelD, the selenium donor protein, which also acts in selenocysteine incorporation. Although the members of this protein family show a fairly deep split, sequences from both sides of the split are supported by co-occurence with, and often proximity to, the selD gene. [Protein synthesis, tRNA and rRNA base modification].	3.82374e-108
NC_013517.1\|WP_012860448.1\|1051803_1052178_-\|hypothetical-protein	gnl\|CDD\|319899	cd06588, PhnB_like, Escherichia coli PhnB and similar proteins. The Escherichia coli phnB gene is found next to an operon of fourteen genes (phnC-to-phnP) related to the cleavage of carbon-phosphorus (C-P) bonds in unactivated alkylphosphonates, supporting bacterial growth on alkylphosphonates as the sole phosphorus source. It was originally considered part of that operon. PhnB appears to play no direct catalytic role in the usage of alkylphosphonate. Although many of the proteins in this family have been annotated as 3-demethylubiquinone-9 3-methyltransferase enzymes by automatic annotation programs, the experimental evidence for this assignment is lacking. In Escherichia coli, the gene coding 3-demethylubiquinone-9 3-methyltransferase enzyme is ubiG, which belongs to the AdoMet-MTase protein family. PhnB-like proteins adopt a structural fold similar to bleomycin resistance proteins, glyoxalase I, and type I extradiol dioxygenases.	3.25226e-08
NC_013517.1\|WP_012860441.1\|1039917_1041117_+\|2-dehydro-3-deoxy-6-phosphogalactonate-aldolase	gnl\|CDD\|239438	cd03322, RspA, The starvation sensing protein RspA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subfamily share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and catalytic residues, a partially conserved Lys-X-Lys motif and a conserved histidine-aspartate dyad.	0
NC_013517.1\|WP_012860459.1\|1083868_1084408_+\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	1.92871e-36
NC_013517.1\|WP_012860460.1\|1084689_1085430_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.85207e-26
NC_013517.1\|WP_012860443.1\|1042205_1042451_+\|DUF333-domain-containing-protein	gnl\|CDD\|377156	pfam03891, DUF333, Domain of unknown function (DUF333). This small domain of about 70 residues is found in a number of bacterial proteins. It is found at the N-terminus the of AF_1947 protein. The proteins containing this domain are uncharacterized.	4.04442e-21
NC_013517.1\|WP_012860442.1\|1041189_1041903_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	6.15574e-46

>NC_013517.1|WP_012860451.1|1055853_1062867_+|autotransporter-domain-containing-protein
MRKNKKLLVSFLALNSVLSMYNTAAPVTVKYNRMYNNMVKNINQGKSNEKNYETIQKILNQKNKELKDLYLQGEYIVKPEYLEWQVFFTGFYDEYGKGVDNSAENAEYHSKVTGYYDAGGNYVVTSGSIKGLAGKGYRALQQPKDINLGVSIPLKGLSREPLNLSLTPAGEININPGSQNVTPPVFSINPTVTTNTFNIDIPNITVNSPTVPTPFSVKPPGTGNGDETYTALRPTDVGTTYRGYTAMISQYNLTTGNMTAHFSGSGYTGLGSCTSGGCLTSYDVENLNGAIDWRVGSGANYGATDPVINDLTVSSAPGVGKAVYDSLTALYKITAAEKIILGIPNNPVGGTADNLVMTLDSKATGNDMPHLIQFDPHTNTNRKYTAYIQDHYGNATGRTNTSDQESDTDKRVQYYYNVLENHGLLQLKGSNGLLIGLQSHNGVVSAVYENYGEMIGLNEGTNPTNHVAHAFIAAQNNSYNHRRFEFYNKPGGLVELRAKSSIAYYYGDPNNYISNKAPHYNIFNEGRIVLYGSENIGISTNGASRDPEGSKIVLYTPIEINGDNSIGVEISKLMDDGYETPVAENPSGGANTYDARPSAIRVIIGKEENKYAGNSTGLNSAGNPFEAGYVEDSVGLYIDKAGLTYRLKDFGFEFGDYARYGKLVYLKAGTLYLDNRETTDINITAGKDNYVFISDSSSSDLTVNPNLNIGTEAKPVNGTIGILGINNGKIHFGASNSIKTYGENSHAVIIQGGSVLNNAAAGLNHSFEVNGKGSIALYVNQGTADFSNSPEINVKAVGEKAVGVYNSSGVVKLGASGTGTGIYTADGLNSVLFYNKTTNAANSIETSGSIFTVKNGGLFSYIENKLSAPQIKFTNTGGTTLNLSDGARGFIYTGNNTSVAAADIQNYFNDNYSGHGNMTVNLSSNASLFVIQEFGSISLDDVNTVAAGTGIFNQINNTGGKNAFLTKGTLVLNPASNLVDLDSPSELYLNIDKALLGITVNSGVAVKGTQDGQAALADDNSYDAVLHVKMENNGTIDLQGKSSIGIYTNNGKITNNNIINVSGDSSLGIFSENGTVTSNTGTINIGNGSVGIYGISHQNPASVPAHGGGLIDIANTGVIRASAGTGAIGIYADNNRTGGIASDADIDLSTGTIDVKNSENAVGVYVNKGTIVDSGSRITVGKNSVALYAKDSDVSLNGIIIDLNGDNALGIFLDGTSSLATTGTNIINIDGRDIILFNMNSSGAVSNNFTVGSIAPGSTYTLGNITGGVFKYTGNSELASNGTLVTGKESAVYLDGSTVTSAAGSVNVAAIALNDQYSGLLPLPAGMTAGIDGENNGTIILGDGSAGIYGKNGSRISNKGAITVGSSSAGLMTSGSGSKVLNSGMITVGTGSQGIYLKDGISAENLGAGNISGTGAGTIGIYADSNISTMQISNDGIINLSGDKSVGIYTTGTNSYLIDNNSTGIISIGNSTNTSDPGIGIYGSTAGSIITNHGTVSSGENSIGAYSSSGTVDNNGIFNVGNSGVGIYSSNGIVNLNTGSAINMGTNGAVAVYGVNSAVTNSSDLNIGDKNYGFILKGGSLTTGAGTNSILGNDSVYMYSTEAVTVINNGNVAMTGSDNIGFYMAKDPVSKTGGGTIVNSPGSVIAGTAGDNNIGIYNYGGIVDNYGMVMVGGSELKLIDGTSDIDVKSSKYSVGIYGEDAAVTNYGSGLITAGYGGFGIVAKGGTASNFGIIITNGDHSTGMYTEDGIITNEAAGVIDVTGKNAIGMAGKGEGSQLINHGTINIDGDGAIGMYGNVGTVIFNSPTGIINVTGNGQAFVSADPANSSHNIENGSAFINGAITANVIESIGSSHTLPTLINAGIIKSSGILALDGMQVMIKPDPTTKQPSSDPDYDFELSGTSIIADQVTASKPIVILPGFSDGLIANVIKLEGLIQATSGQYDFISGSLLWEATPKATGSGSDVYMSRKAFTEFTDGLWFEDFGTALENNYMTASGDGITIYNKTGYITNETDFRHIMASLAGNVYANINQRENDIARTFEDSMHLLQNSVNNTKENVKISVIAGKGKNKEETDGVVSYDYATTGVLALREVERTYRHTFGYSVGYLHTGFEFNDGNSSEEWVDTIQLGVHNKYKSGGWEVRNDLTGRVSFHNVDRNIDWPSPLVRSEMNGTYETYSLTSDNILGKEFGLGKKASIMPYGAFRAMYVTRPAFDESGLEALEVEGNDAWSAKPRAGVELKGSVPLGAKSAWKLKGTLDLAYEYELADLNEREKARLTAIEDGYHELSKPQEEKGAFRTRAEIGVEVEDRYGVFITGEYLSGNDKEDDYRAGVTLKAVF
>NC_013517.1|WP_012860450.1|1053647_1054565_-|hypothetical-protein
MKLYSKEEITKQMRLHYSEKKTITMKSFNENKNVCCSTTVKRYFGTWNNAKKEIGLSSGIEYNKLKLLAAIKEKINSGEIKRISDIDKIADLPSYKYIKKLWTIEEMEKIFGIKIKKYSYTAESIALQYNKVKKKHNKITFELLKKETGISAGTIRKYFKSWNMFLRYMGEEPNHIITSVTHTNEELIELYRRISIKIGKEKYGATSRDLKEYDFPYSKSVLASRFTSLNYLRKIAGFEIKREITPKYSKQGIKLMLYNKYKKYGRKLTQTEIAKNESLPNPSSIFYYFQTTKISDVWKEVLNEK
>NC_013517.1|WP_012860449.1|1052378_1053407_+|tRNA-2-selenouridine(34)-synthase-MnmH
MVTAQSYEKLSESKGKIIFIDVRTPKEYEEARIPGAVNIPVFSNSEREIIGTIYKQEGKRNAIKEALKIVGPKVLELYMQFEEYHKGKNRMVVYCARGGMRSSTVTALMKELSLPLVKLEGGYKGYRQYINEKLPLLVKKFQFITLYGKTGSGKTDILKRLKNDGYDILDLEACANNRGSLLGDIGLGGRYSQKYFESLVFESLVNAKNDILITEGESRRIGNIVMPTYLYEVLINSRKLYIETSLERRTEIIRKEYLKDGVEQEEIIKSIERLKKYINEKQVQEFINGVKNEDYDNVIKDLMIKYYDKVYSSKGKTYERVFNNDNEDRCVKELTDYIFSEK
>NC_013517.1|WP_012860448.1|1051803_1052178_-|hypothetical-protein
MERTLMQVYVKGSAEAVELYQKAFNTTLGYNVVHEDGTFYHSELNVYGQIISVAERTDDADSITGNTMQFCLQFSKEETDLLKKAYDILTDNAKILFPLGPCDYTTHLADLIDKFGVRWCLFVG
>NC_013517.1|WP_012860447.1|1044682_1051612_+|autotransporter-domain-containing-protein
MKKYKKFIVGFLALNSMITSYSETLGVQSSGKYDRIYENIIKNINRGRPSDTSYKLIEQMLKKKNKELKDLYNQGDYIVKPEYLEWQIFFSGFYAERDKGDNTEENAERHSDPTYGTTGFYDEDGRYIITGTNKAAYGKEYRDPQAPRTVNLGVSIPIKGLSRGEVHLDLPSGSPVEINPRNYDVSPPSGLVIPEINVFRFEINIPSVVLPVITTPGSFTVSVPDTGNGDDTGSYLGVANSYTAKIAQFNLTSGLLEGTWSSTSSLSAYRAVNLNGKSDYGGTTMGSRADITNYTYSSNSGDGAVALYKVGGAEKITLGTQGDPNAFIMRIISNVGDSYPAASTLPHLIQYDPHGSRGTYNRYLTNYYGTGITPSGIFDYYAELNNYGRLEGIGDSFLMIGLQEHTGNFSPTVKNYGTIIGIADDQYTQGGRRHVAFSFMAPQQHGTQGRRFEFYNMTGGKIELQARESIAFNFGASPGLATRPHFLIYNDGDVVLYGNNSVGVKTANNNLDLPYSKLVFNKPIRINGDQSIGVELVKTMDDGYGNVEAGKYDPMEAVIKVIIGDEPNSNTGDSKGDKSKVEESIGLYINKSTIDYRLGTFDFQFGEYAKRSTLINISSGKLFLDDNKVSEIFINKGIDNFGIIATGSASELTLKPNIKIGTAADNVNGTIALYGTNGAKIHLHSGNNIETNGLNSHGIILTNSNTVLDDTSSGGSNHSFTATGNESTVIYTENGASVNLANSSNIDVKATGEKSIGVYTKGGTVTLGTAGTGTGTYEIGKNGVLFYSDGTGNGRINISGTDFTVGEGSLFVRINTPSLIAGNQQINFTHNTGNTNLNLLSGGIGFVYTGDGINPVGLSDIQNYFSNNFTGISNMNVTVNKGARLFVIEKYASMNLSDIIAISSPTGLFNDVRNNGGSKAFMVRGNLVLDPAGGVINLDDINEDYNNIERALTGITVPSGVTVTGSGDRQTALVDDNSYDSTLYVKMENNGTINLTGNNSTAIYVNNGQIDNKGTVSSIGNGGIGLFGENGTVIKNTNLITIADNGVGIYGISYQDPASVPVYGGGKINITNTGIIQSNTGQHAIGIYAENNRTGGGIADSHIDLSNGKINLQNSEGAIGLYVDKGTVTDSGSEITVGKNGIGIYAKDSDITLTGTTVNLFGDNALGLYADGNTNLIGNGQINISGKNVVLFNMVSSGSITNNFVVNNVAPGSSYTLGNISGTSFEYAGSSHLSSDGTLISGKDSTILLNALSSVNANSGEINIAALIADGQYTGITPSGFTPGIEGENRGTIIMGNLSAGLIGKNNARLKNDGFITVGNNSAGMTSFGGGALLLNTKSIIIGSDSHGMYLQNGTDITNDTGGIITSAGNNSVGIYADAITGTITNKGIIRLTGDKEIGIYATGASNKIINNDGLIEIGDSIDINVPNIGIYSETAGDTFTNNGTVTSGKNSIGMYNYGDTVIQNGILNVGDTGVGAYITNGNITNTTAAQFNFMSINAIGVYALNSQVSNSALMNIGNSNYGFILMDSSFINMAPNINLGTDSVFVYRSGAGNIVNNAGTAIAMSGSDNIAYYTINGGSITNDGDIIGTAGKNNVGIYNVGGGILNNGIVAIGDSDIAYKKDSLGNYIYDVNGNRILDAENSKYAVGLYGEGSAISNSASGNITVGEGSIGIATKGGSGINDGVITGTGESTRGMYTEKGTVINNNIINITGDNAIGMAGNGAGSVVINNGTVTVTGKNVIGLYGNLATTVINSGTVIANGEGAAGIVLSQGSKLDNTASGTMIINSVRTENYGTSAGEIYETPTIINSGVIKISEKFETDGINVVIKVDPESVRKPTPEEIAAGGYDPSDSGADYLISNAVSIEAPSFTITDPLQISGNFTEGTNVKKYKLEDIIKSASGHGVNEGMVPVVSRSLTWRATPIVNEAGHVDIWMEKIDYNEFTGGLWYEEFGAALEDKYYNAAGDALTIYDKIDVIEKESDFRHVMASLAGNIYSNINQREEDMARTFENALDVIINSKNNTKENIKINIIAGKGKTKDDTDGITDYDYTTTGILALREVERTHRHTFGYSLGYLHTGFEFKDGNESEELVDTIQLGVHNKYTVNGWKLRNDLTGRVSFHNIDRNIDWPNRPFGTEREEMNGNYETYSFTSDNILGKEFSIGKQVSVMPYGAFRAMYVTRPTFSESGTERLQVEGNDAWSAKPRAGLEVKGEMPLSNKTAWKLTGKLDFAYEYELADLNERERAKLIAVEDSYHKLSKPEEEKGMFRAKALFGIEVEDRYGLFLTGEYMTGNDDQDDYRAGVTLKAVF
>NC_013517.1|WP_041309814.1|1043139_1043529_+|YbaN-family-protein
MEVILKKLFKGIYIILGIIFLGVGIIGIVLPVLPTTPFVLLASFCLAKGSDRINNRFKKTKIYREYILNFKENGLTKKQKIRIVLTADLMLLASGYFVNNFHVRIFLFCLALIKTAVIFRIKTNAGEPA
>NC_013517.1|WP_012860444.1|1042784_1043000_+|hypothetical-protein
MKFLMKFFRKITCFKKLDHTKFTLESQYLEYKDSDYKYYYFKDIRTNRYVKVLKEENDEKLDIYTNWLNNK
>NC_013517.1|WP_012860443.1|1042205_1042451_+|DUF333-domain-containing-protein
MKKLSGLLILIGLTACTSVKSGTGSENTKIGMPNPASKYCVEQGGKSEIRKAENGGSYGVCIFKDGSEEDEWEYFRKNNAK
>NC_013517.1|WP_012860442.1|1041189_1041903_+|GntR-family-transcriptional-regulator
MKKKEFVAQDLLTKIYQNLYKDYKLPTERELALKYNVSRHTVREALKKLNNIGIIEIIQGSGIFINRKFHQSPLIYNSITEKKYNQIKSKIIYFVPKKPGKEEKQIFDLKEDELLWEFQRVRIVDYKITQIEISKLPVHLFRDLEKKNIESSIQKYVRDKNLEISHYITTYEAVSINREQAELLKCKKGTPAMKILNRGILENGMVYEYSEIIDIDYSCTYFIPFNKQNHSFRQLVP
>NC_013517.1|WP_012860441.1|1039917_1041117_+|2-dehydro-3-deoxy-6-phosphogalactonate-aldolase
MTPTIIKNIECIVTKPGRHNLTVVKVETDKNITGYGCATFQQRPLAVKTMVDEYIKPLLTGRDANNIEDIWQMLMVNSYWRNGPVINNAISGIDMALWDIKGKLAGMPLYQLFGGKSKNAVPVYTHAAGENLNELYEKIEFFLNKGYRYIRCQLGFYGGNSKEIHMTENPVKGAYFDQDEYIKTTLFMFKSLREKYGDRFHILHDVHERLFPNQALRFAKEAEKYNPYFIEDILPPDQNEWLSQIRSQSSVPLATGELFNNPMEWKNIIINRQIDFLRCHVSQIGGITPALKLAALCQTFGVRMAWHTPPDITPVGSAVNTHLNIYLHNSAIQEYVEEQEAVLTVFTGAEKPRDGYLYPAERAGIGVEFLEEEAKKYPVEYRPHEWTQSRLPDGAIMTP
>NC_013517.1|WP_169305389.1|1071102_1071255_+|hypothetical-protein
MKIKNKNNRKNSKIISFLQGNMMKKITGKEEPDNNRNFSFRKQHVDGIFA
>NC_013517.1|WP_012860453.1|1071488_1082546_+|autotransporter-associated-N-terminal-domain-containing-protein
MKNILGYTERQLKSCLKKNKRVKFSKSLPLIFLMTGNILNAGEEPAMGRVAENLQKKIKKLRDENKKNLRYSRLELERLEKEGDQVIKSPWESYIFSTLFGYKDMDSQSKEWKYGDRKDTMQDMDRAVLRSFLGLSSLRGGTTGWITETNTGDGEGNAWTVNTSVYDNTAQFTIIPTIKVPEVTTPLSPQVDLPSINVPVVPGAPAVTLTPVNVGTISVSVAAPSITGAIPAVTLNSPNDVSISTIAPNINVSVDEVSGPVISTVNQPVISFTPPNLSVAPQVPPKIKVPTPTVTAPVSPPAPSFEAFTRGRGDWLGGFSFIQGRNNFDRKILAWEQGSPAPSQRGINSQPMFNIGGTISGHGKNTSSKIYATTSPLGVVNNQYTDIRLSNAAAGGKPTNQYGAIPYPTVVVSPAAFPSNLAGEWVSAVDNDTLQGFSTSRYQQSWIFQGSPIVQDMDIIVGGSATYSTALFAQTGSIQMNRVGLELKGKTIIGQLSIRGAYNVKFTDVDINITGDSNSLLTTQLYPNTHVYWQSSDGRNSTTWGSSYLDNVASTTAIDFGGTKLVADRSKNTIVYVAPAEMHRWLGYSQMVPLPGTTSPTVYDVNAAKYYMYAPVMGNVNVKNTGGDVEYTGSGNVGIWVAGYVPDRTKWATGLAPSLDLGTVKLQGDKNVGFYLASHDTRPDANGIFQGNINVNVKLGTDIDGKGGTTQTGTGNISGNSNTKSEDNVALYVSSGQRAGMNNTVGTAYQEYFPATLDFKVDKSVTPNLVGINNGTQIGFQYLTADPIRDLSVTNFNLEFGKFSERGIGIISKNGSVVNVNKGTAISDNAGTGADRATGTIMFYSEGVWFNPRKVLTGGVYNKEAYGRGESQTGQKNIVDFNSTINVSNNVSMSSYEAIAFFAKNGGKITGNDVTMTGHSSIGAFAYGANDFDSSKTVLANNTGAGSQASTTITLGNVTATGLGSAANKNDGSNSNVGVAALSISNDELTKGTGNTAVTVTGNLNVNGVGAFAKGDKAVIKILGTNSTVNTGENGGLVAQKGGKVEFGGGTITHKIADKVAFYSDAKAGATVSTIDFKGGTTFEMYKGIAFYGSKSDFDGTTGRYLGMNNVTVNLRDNGINLGYFQYSSSESDADRTINWTGTNISTYLNSLKSRVGNATINDNGFWFKSSLDGAIVNVNGDVNLDYASDDSGGTPDKFNDITIERSKVIVNPGITVESIDKGNGLKMASNTSAANNTETGYTIKGTVNIKDPTVTGPGAKENVGIYTSFGHINNTNTGLIKVDKGVGAYGVNGSQIINDGVIEISAKTNNTLGGIGLVGVTRKVKADGTVDTAENYGTDNTSNPSMASLPLVDIINRGTLNIYSAGTTPASNATGIFAENNTGGARSRVKIHNESEAIILGNESVGIKVKAASGITEGGTLTLKHKTGVSGPDIKVGETSFVISAEYSDVKFDGNYTVEMGRESVALNLTGNSTVSTASAADVLTVNYDYNDPGITTAPKYGTGIYYTGKIGEIVTNNLNLALQPAGLISDDNNALVGIYAAGAETNTSNITKLYNNGNISVGNYDYGIYGKNIYTINTGNIEVKDNGIGILSDEGRVETADNKIKVTGDKGIGIYAGAVSGTYNRDVLINPGMSGKLEITGEEGIGVYLEGKARLDNKGTIEMADSNTPGALPGEILRKTGVYLKNSDTANESTGIIKVNKNNIGVYSLNSRFENKGAGLVSVEDTTAAQNIGIYAVTSNDAAADNFLISNSGTIEVKGLKNIGIYSEIKDTASAGDTGHINLSSGRINVTASDPLTDSNIPLGVYAKGQNINVSSVSSITKVSENGIGIYIDGISTLGNSVNAFNGGFTLKSAALSTPAIGAYLKNGAQALAGNINVISTGTANDSSGNPLRPIGIFYAENTGALTNGVNITLTNDGINLNQETIGLYAEKNNSLTNTGNITINANSKGIGGYFKDTNLINSGAVTVNADGAYGLYVKSDGAAVTNSSNSGLINVNNKEAVGIILDDKAKLTNTAVINSTAGGNAAQNGSMGVYVTNQGNFVNDVSGNIYATAAAAGTNPGSVGIYIKNGLADNKGTITSDYVGLYAEKDSSLASSSTIADHTGTITINNGIGIYAKDTGTQINLNAGGAINGTVNGLSGVMAYDKASVKLAGTNISLTGDQSNAIILGNSTLNTDKSVLDLNSGNITVGKEGTAIYSKNGIINIAGGYTGLITLGEKGTGVYADKDTAVSAGTLETVYSHGTNKGVGIFYDGGIQENKVTIKQHAGNNNLINIYAQDIALVNNADQEVSQNGIGIFVKGPGLATSVENKKTLSLTGTNSVGIVTEAGSAVTGIGKIAGINGKHDKIGVYVKGGDISGTAGYEFDIDGGIGIYLNNAVSYTGTMELKGGVYDDSLNKYRAIGILAAPSFGTGTLSAGIDMTGSGGIGIYQENGTDITYTGKLDIKGTSTAADQGIGVYTKAGSQFNLASGGDIKIGGTNNIGFYVESGGILNVTGGTVTNTEDGIFAYLEGGSMTFTGGGTNINYANVIVASGGSLVNQTTIATGKTGLQATGESPLLVPSTILNDTGGIINSSTLNAVAMTGLDKAYIENKGKINLNGDGSIGMYVRDADGLTTGEVNVGEKSVAYYADGINGKMIINGTSNIGKNSTLLAVADGARIDYQSGAINLGDERYGALIDGAASIIDFGGNNITTGNKSVAIMLQNGGQLNTTLHDITVGSEAVGIYLADFTNVISPLSRTINLGTGSTGIYGENGGNIQLDGSILSAAYGAKGIASKNSAVTWIENSGMINLSGAASVGMYGEGIAQIRNSSGKTIKIGDGDTINSKSGVGIFGLNSDSIVNEGIIEFGNEAAGIYGENITSGIENRAGSLLTNNGGQKGTGIFAKGSMVENRGNIAMGDASNGIYSDNGLVNNYSNITVGNDKSAGIFTSGTAAINHISGTVSAGSDSVILASESGNIINNSTLISTGEGTTYIYSKAGNGETNTALTLTDYSVGMYGQSGTMTNKSVITVGKSDVAAGKFSVGMATETGNIINSSGALITVGNEAGVGMFASGIEVKHSDGTVTFGPSGRAENYGTIDVTGLKAYGMLGTNGATVYNDSNGIINVDGTGAKGLVGTNEAHLINNGTVNVNGQDAQGVYIEKGATLTNTGQINVSGAGRIGVFVGMGSSFVNTAGITISSGGTVVLDGGGTLANIGDIVIDGPNATVNGITINNTGKIEVTGTINFTDNILLETTPGKTGTINVGGISGTGHIILSPGATLGNNYDMYHVQLLGGLHNPTTETIRLTSQSVSFLAEKYFDKDLNSYVLTLTRIPYAQMLKNTEAVEFGKGLDELYTKGPSGSEMDMFDALKSVSDKDELAETFDMQLRGNVYANIQQRMMDVSGVLDTAYKQLKSEENTTKDITKVSAIYSGGNITDKNPGVEEYDYQSLGIMYLKEKETLKYGTNFNYSLGILQSKFDFDQGSKEDITSLKAGIGYEQYLKQGSRFKYMTRGELGVNYHDMERKIYLSNGTYKNNGDYFSGTAEWKNRLNYELPIISKNFKMDIFGSLNTGYGKFQGFKEDGDGMYLDVKSEDYFSLRPGAGVEGEWSYTTVKGSKFMLTAGAAYEYETQDIYGDGNEVKIANTDAGYYRLEEPEKIDNIFKANVGVGYETSGGFKTGVRVEREEGSVKGTKYQLDFSWKF
>NC_013517.1|WP_012860454.1|1082614_1082989_+|hypothetical-protein
MKRILLCLLLGTICFGYTRMSTLTEEAGKINSAETARQERLQRRKEKLENDLEKLYKNYDSRAEITEKLRVDSEVRWYRDEYREILKKYDDVQNNLNEEISKKEKELALVNIGLGIQEEPVLED
>NC_013517.1|WP_012860455.1|1083020_1083263_+|hypothetical-protein
MKKMILPLLMCLFVSHGLLAAPKLKSGKKTESQKMQAEIDRIEKRVNEINNNIEAYKENEKKLDELEVKYEETVTDLRLK
>NC_013517.1|WP_012860456.1|1083275_1083416_+|hypothetical-protein
MKKYLVLVAVLFLLGCTSGETKRTIEDTKERVDRTEEYLWENQVKE
>NC_013517.1|WP_012860457.1|1083432_1083657_+|hypothetical-protein
MRKMILTGLFLFIIAPLAAEEIIIEEAETDVKLEKAEAELDYMKEKVDFYKRVVRSVQREEEELKALKRIRVRK
>NC_013517.1|WP_012860458.1|1083674_1083872_+|hypothetical-protein
MKKKLLLLMSFLLVSCTTNKALVEYNRVRMDKNEEYLRNVENKTVPKGEVKGTTRREPLEKEADR
>NC_013517.1|WP_012860459.1|1083868_1084408_+|OmpA-family-protein
MKKKIILLLFVLAVFSTARPFTTKQMRNDTIRINALEVEFVEEKAAVQEVKQNGSGEVKKIIRLNENKLYFDFDDSRIKPEYYGLLREMVEEIKAMDSDVIIRGYTDSKGTDEYNNRLSQRRAESVRDKLIEFGLESGRVLKTEGMGERNPIAPNTNKDGSDNPAGRALNRRIELELVK
>NC_013517.1|WP_012860460.1|1084689_1085430_+|class-I-SAM-dependent-methyltransferase
MKENKYDDEKFFNQYKKMARSTGGLEAAGEWHEFRKMMPDFQGKRVLDLGCGFGWHCRYAADNGAKAVTGIDISEKMLEKAKEMTESPVIEYILMPVEEVDYPSESFDAVLSSLTFHYIDSFRNMCKKIYNFLTDGGYFVFSVEHPVFTAYGTQDWYYGKNGERLHWPVDRYFSEGLRKANFLGEEVMKYHKTLTTYINDLIWAGFEITGFMEPKPEESMLRDIPEMQDELRRPMMLLISAKKRKR
>NC_013517.1|WP_012860461.1|1085525_1086284_+|DKNYY-domain-containing-protein
MKKVILFFGVIVIVLVLGISIVKIIEEGDYDYWSHYFDKDYLAFKGMKNSDAKYLLRAIELGEKSTWAYCTLASVYVEDKNDDLAEKYYKKAINKLDTESIKILDSRYIKDKNNVYLECSEIKERDAESFEVLSYFYTKDKIRVFYVDEELKGADTETFTILNSDYAKDKNNVYYNNKKINKADQKTFEAYENYGKDRNNVYYREILMKDADSETFTENKVWQRTEDGIEYMAEDRNNYYAGEEIVKEKDRN

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Crispr_ID: NC_013517_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_5

1415582-1416007

Orphan

Consensus_repeat	Method
CTATTAATATAACTATCCTAGAATGTAAAT	PILER-CR
CTATTAATATAACTATCCTAGAATGTAAATT	CRISPRCasFinder
CTATTAATATAACTATCCTAGAATGTAAAT	CRT

6 spacers

The CRISPR arrays of NC_013517_5

>merge|NC_013517|5|1415582-1416007|PILER-CR,CRISPRCasFinder,CRT
CTATTAATATAACTATCCTAGAATGTAAATTTCTCTAGCTTTTGCAAATATTTTTTTCATTGTTGCCTATTAATATAACTATCCTAGAATGTAAATTCTTGTCATGGGAGCGTTTCAACTTGATTTTTACAGCTATTAATATAACTATCCTAGAATGTAAATTTTTCTAATTCTTCCGCAACTATTATAGTTTTATCTATTAATATAACTATCCTAGAATGTAAATATAGTTCCTTGCAGTATTGCAAATACAAGCAAGATTCTATTAATATAACTATCCTAGAATGTAAATTATAAAACAAAAGTAAAGCAATTAGCTGATCTGTTTCTATTAATATAACTATCCTAGAATGTAAATATGTACTCTTCCCAGATTAGGCCAAAAGTTTTTTTATCTATTAATGTAACTATCTTAGAAGTAATACA

>NC_013517|5|1|1415582-1415939|PILER-CR
CTATTAATATAACTATCCTAGAATGTAAAT	TTCTCTAGCTTTTGCAAATATTTTTTTCATTGTTGC
CTATTAATATAACTATCCTAGAATGTAAAT	TCTTGTCATGGGAGCGTTTCAACTTGATTTTTACAG
CTATTAATATAACTATCCTAGAATGTAAAT	TTTTCTAATTCTTCCGCAACTATTATAGTTTTAT
CTATTAATATAACTATCCTAGAATGTAAAT	ATAGTTCCTTGCAGTATTGCAAATACAAGCAAGATT
CTATTAATATAACTATCCTAGAATGTAAAT	TATAAAACAAAAGTAAAGCAATTAGCTGATCTGTTT
CTATTAATATAACTATCCTAGAATGTAAAT

>NC_013517|5|5|1415582-1416007|CRISPRCasFinder
CTATTAATATAACTATCCTAGAATGTAAATT	TCTCTAGCTTTTGCAAATATTTTTTTCATTGTTGC
CTATTAATATAACTATCCTAGAATGTAAATT	CTTGTCATGGGAGCGTTTCAACTTGATTTTTACAG
CTATTAATATAACTATCCTAGAATGTAAATT	TTTCTAATTCTTCCGCAACTATTATAGTTTTAT
CTATTAATATAACTATCCTAGAATGTAAATA	TAGTTCCTTGCAGTATTGCAAATACAAGCAAGATT
CTATTAATATAACTATCCTAGAATGTAAATT	ATAAAACAAAAGTAAAGCAATTAGCTGATCTGTTT
CTATTAATATAACTATCCTAGAATGTAAATA	TGTACTCTTCCCAGATTAGGCCAAAAGTTTTTTTAT
CTATTAATGTAACTATCTTAGAAGTAATACA

>NC_013517|5|1|1415582-1416006|CRT
CTATTAATATAACTATCCTAGAATGTAAAT	TTCTCTAGCTTTTGCAAATATTTTTTTCATTGTTGC
CTATTAATATAACTATCCTAGAATGTAAAT	TCTTGTCATGGGAGCGTTTCAACTTGATTTTTACAG
CTATTAATATAACTATCCTAGAATGTAAAT	TTTTCTAATTCTTCCGCAACTATTATAGTTTTAT
CTATTAATATAACTATCCTAGAATGTAAAT	ATAGTTCCTTGCAGTATTGCAAATACAAGCAAGATT
CTATTAATATAACTATCCTAGAATGTAAAT	TATAAAACAAAAGTAAAGCAATTAGCTGATCTGTTT
CTATTAATATAACTATCCTAGAATGTAAAT	ATGTACTCTTCCCAGATTAGGCCAAAAGTTTTTTTAT
CTATTAATGTAACTATCTTAGAAGTAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012860778.1\|1411650_1412295_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|274805
NC_013517.1\|WP_041310499.1\|1418564_1418846_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860779.1\|1412313_1412721_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_013517.1\|WP_081439686.1\|1417973_1418165_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379188
NC_013517.1\|WP_012860780.1\|1412701_1414306_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_013517.1\|WP_115388835.1\|1409718_1410012_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860781.1\|1414400_1414565_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860788.1\|1418872_1419169_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860773.1\|1406714_1408241_+\|DUF3696-domain-containing-protein	unknown	unknown	gnl\|CDD\|227274
NC_013517.1\|WP_012860785.1\|1417481_1417769_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860774.1\|1408240_1409296_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_049768974.1\|1420585_1420948_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223829
NC_013517.1\|WP_012860789.1\|1419264_1419915_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_041309842.1\|1411253_1411610_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860790.1\|1419915_1420482_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860783.1\|1416135_1416681_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276807
NC_013517.1\|WP_012860776.1\|1410437_1410869_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860784.1\|1416778_1417489_-\|antirepressor	unknown	unknown	gnl\|CDD\|226144
NC_013517.1\|WP_012860782.1\|1414609_1414987_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012860791.1\|1421254_1422157_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381391

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012860778.1\|1411650_1412295_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|274805	TIGR03830, transcriptional_regulator_XRE_family, putative zinc finger/helix-turn-helix protein, YgiT family. This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.	7.64747e-21
NC_013517.1\|WP_012860784.1\|1416778_1417489_-\|antirepressor	gnl\|CDD\|226144	COG3617, COG3617, Prophage antirepressor [Transcription].	8.23728e-33
NC_013517.1\|WP_012860783.1\|1416135_1416681_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.40965e-14
NC_013517.1\|WP_081439686.1\|1417973_1418165_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	0.000741386
NC_013517.1\|WP_012860780.1\|1412701_1414306_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.96905e-20
NC_013517.1\|WP_012860773.1\|1406714_1408241_+\|DUF3696-domain-containing-protein	gnl\|CDD\|227274	COG4938, COG4938, Uncharacterized conserved protein [Function unknown].	3.40414e-13
NC_013517.1\|WP_012860779.1\|1412313_1412721_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.18543e-10
NC_013517.1\|WP_049768974.1\|1420585_1420948_+\|hypothetical-protein	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	2.9296e-17
NC_013517.1\|WP_012860791.1\|1421254_1422157_+\|aldo/keto-reductase	gnl\|CDD\|381391	cd19752, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	2.6374e-102

>NC_013517.1|WP_012860782.1|1414609_1414987_+|hypothetical-protein
MVKTSGADKQLEFLNKNAQLIKAKSVSEAVEVLQAEYNAMEKEVIFFDGIETIKFVVDKANLIPVVPENELKLLKIMNLSYMLGLDLSLGTNYMEKTGEILLNDDIEYQRTKYRSLKALSESSGK
>NC_013517.1|WP_012860781.1|1414400_1414565_+|hypothetical-protein
MVEKILIILILCLGTLGCDAMLSEADKQLKVIEKLEKIFQKSWKITDKLLLDIV
>NC_013517.1|WP_012860780.1|1412701_1414306_+|tetratricopeptide-repeat-protein
MKIKETKEQILLKEMKENLSDIYNQLGITYSEMQEYDKAIKNLDKAIEINPDNSLAYNNLGFIYSEQKDFENAISKYKIAIEKGNTIAYNNLGTIYLSQERYKEAEDSYKKALISFKDNSMILYNLGIFYFEQEQYDEAIKFYEKSLEIQDDEATRFHLGLVFSLTNQYEKAKNNYEKVTKNPRFSFPYLNEIYLQMIKNIKELDSEILVRIILMMYFTDEILKRCHIKIDNIAHYTSINVFSKILEGKKNEEDEKIKEKFLRMGISHLCNDPTEGHLLYNYLELPIERLIEQYLCFLTCFSLDTDSLNQFRLYGKENGREATGVAIVLNSSFFSKDFNNLDYFCEKSSSKIKFEETNKIIKTEHRSLYRCIYFGFDNKNKERIYCKLAKRSEWSEFNEIHKSQEDYDNLEKLEKEIENSIKKIMEHNNMLVETKMTKVTNLIPEILMPLRYLIKDPAYEEERECRIIKILKFGNEEIIEDNELKRIYSEYKVNIEDHIAYINIHQRQELYTTFFQNKLKDRNKVKISKNPFNG
>NC_013517.1|WP_012860779.1|1412313_1412721_+|tetratricopeptide-repeat-protein
MSDVNLKKNIVEEIDEMVKKIKEARENNEEYKSRVENLVLYSLDNGEYQKVTDAIESLGLSSEGDSSLYNNLGVLYIRQNLYEKSIENFEKSIEMGNKNIGVYINLSRVYLEEKKFNDAIETLEKAKNIYENKRN
>NC_013517.1|WP_012860778.1|1411650_1412295_+|helix-turn-helix-domain-containing-protein
MQIEKIVSKKKTYKVKNLDITFIEQTKINIETGEEIFDSKLEKENGIRVTDEYKNQVGLLTSNELKKIRNKYKISQIEFALLLDLGEKNITRYENGMIQNKSIDSLIRLMKNNMNFLTLLVENKNNFSNERYYELLRNITLKILQENLTQNIMIDSRKNIPVRSRVVAAPFSPRKAKNRNRRIKENGMIQVSKIGNRKIGENEKSEILKSRFYK
>NC_013517.1|WP_041309842.1|1411253_1411610_+|hypothetical-protein
MSETIVSLLETVRGYIVNGEYDFLVYREKNKKTLEDYGITAEFLVSNIFDELEPGDLFRGPIPDKDPNKQDGDVYIFMKDINCIIPEISKKFYIKFKIVEENNKKLIILSLHEEGMFE
>NC_013517.1|WP_012860776.1|1410437_1410869_-|hypothetical-protein
MDIKLIEKRHRSKLRLIFGFEILLLGVGFLTYLHMKDNPNFTFLSIANIKFLVPFVIALCGFGVKFKNYFLVKFPVILIIFMVLFLFSGKFSFLYSKDTIFFIRTILFFGLLIFSLGVLLEWEIHIDIKSSIEYEENKTLLYY
>NC_013517.1|WP_115388835.1|1409718_1410012_+|hypothetical-protein
MVLIDEIENFDEREERYDSLRAAAYLLQTLGVVYIWPVEYLNKLKPLLDKTIIILNNMINPPDENWAYLEMGGDKEKLMQAVKEQIDILKERRKDII
>NC_013517.1|WP_012860774.1|1408240_1409296_+|hypothetical-protein
MLIKLDSSIVELNRNYEDEEIYAIQKLINLVRKRYHLIYSKYEVLEKLSKIEDLGCRDRKIFEKLATRIRQKFNFYEKNFKKRLLIYIDTPKEKKSKNDIQIELKDFDKIDETKTNFLVEGKDITFFDFIVNFHFENFNKKIAYNYINTYDEITGGGNTTADNFRKLKKNKIVICVCDSDRDYKNCRLGDTAKKIKKVKILCHEIAHLMILEEKAIENLIPRVIYNPILENKSDFLDKLEKEKEFEYIKHLDFKKGMKKKRFLECKEYKKFWKLKIEEFFKEELDKKLDDLDEESCVIEKVSENLLNSVNKRIETGKINIEYSSLSDYHKKRWQEIAEELICWFICETNPI
>NC_013517.1|WP_012860773.1|1406714_1408241_+|DUF3696-domain-containing-protein
MFKMGYKNLRSLNMEESLEIKPITTLVGLNSSGKSTFLRALMLLKQSFDLNNAAPIIWYNYDNQVDFGSFDEAINNNASEEEIMFSFEFLFSNIISGYSFEDKREEKIPIKINSTLKKSGGKEYISKVEFEFFGNNFLISHEKKNTVKVKINNEIFEEVEKKHWIYPFKLSTLIPEIHVGREKLFAEIDEDIFDVEKLGKLMNKKNSFEIEILGRKKNSKKQEEFLKFFSLIEKILRYEEFAELITKFSKITLKKNDTMKYYNLFLAYNLYKINMNISITLCKIIENVEYITPLRAMSERYYRINSNIRKIDPSGRNLATYISNFSETDMIKLKKWLIENFQFSIDLKESTGHNSIKVIDASNNEGANIIDTGFGYSQILPILINLWEISNKTNKSRQYDKNLKILLIEQPELHLHPAFQAKLTDVIINLVEKTKEKIDFRIIMETHSETIINRICNQIGKGNLNKEDISLLIFEKEKIGTVIKEAEFDDEGYLTNWPYGFFEPEGVK
>NC_013517.1|WP_012860783.1|1416135_1416681_-|tetratricopeptide-repeat-protein
MIKKIFVTFIIFGVFYSCSPSNPEPTVGTEEYYLEKIKIEDRESMFQLGLLYQEQGKFELAEKYYLMASEHSDSNAMNNLGNLYKKQEKFELAERLFLMAIKYDNKLALYNLGLLYHDQEKFKLAEKYYLMAIENNNYDAMINLSVLYYEQGKYKLAEKYAKMAYDNGVEGAKNLLDEIRK
>NC_013517.1|WP_012860784.1|1416778_1417489_-|antirepressor
MDKLQIFQSKEFGKVRTVLIENEVWFVLIDICKILELSNPSSVIKRLDEDEVTKFDLGSLSGITNIINESGLYKVIFRSDKPQANQFTKWVTHDVLPSLRKTGSYSINQTPKELELKEKEIQLKTAEFLNNMADSILIPEYKQILNAHATKVLTGDFLLPLPVVGEITYSATEIGKMLNISANMVGRLTKKHNLRTEEYGKVFYDKSKYSSKEVETFRYYIKVIDILKNIVSTLSA
>NC_013517.1|WP_012860785.1|1417481_1417769_-|hypothetical-protein
MNQNIKEFMISHIEEMYDYGHLKDDLSKMEDNFYNLIENINSKTTCTKNDIQQLINTFETVLLTAKKTYFEHGATSGISNINKMYLTPNEVVLHG
>NC_013517.1|WP_081439686.1|1417973_1418165_-|helix-turn-helix-domain-containing-protein
MEKHNIKSVSSLERQLKMKNLYISRQTLQRLSQNIGVEKMNLSTIIKLKKFFNCSLDDLFTIT
>NC_013517.1|WP_041310499.1|1418564_1418846_-|hypothetical-protein
MPISQLSDDAKIWSGIIVKLYNVGLNVSDKSKDYYEYLISEIYGNNEYLQLTCLSQGEAGNIICVLKKDLPNYYALGKELKRMMKIEDRRYFY
>NC_013517.1|WP_012860788.1|1418872_1419169_-|hypothetical-protein
MTKEKMNELYEKSQEIVTMMEELGIKECNGYVLKSISSGTFLMLNNIYISLSLSYIYINDNLNKFMPTTTLEIMIQFNDDINNDKFIQLEELYQNFLE
>NC_013517.1|WP_012860789.1|1419264_1419915_-|hypothetical-protein
MGEFLKEQNIMLIILNLIISTVIPLIIGFLFNRQLTNLKHNFEIEKLEYQHTFNTEIQEQKIEYEKEIIKLNDVINKNKLVYTLKFKKDFEACFKLWDKYNIYYNLFYELFSFLKANDLNSNTKKISNLITQLDIKNTELNDQIDFYEPFIDNSFHFAIKKSVEYLPSFLLKAYIGEYSKYHFIRYTDSLKTDITQNRTFIKNSLKEKIDTLKEIN
>NC_013517.1|WP_012860790.1|1419915_1420482_-|hypothetical-protein
MILLEKLFSKYTKKELEGIFPRQYVYELVNYRIHPKLTSIAGRVDVVNELNYTYEDFLADHENYAEYKESKLLFDLYKKGITAKDAAIKFDYNETSFLAYLRNGIPLNKGTKIEEIKSYYIEDKIDIKGMKHKIFNNHCELYASKEELEKFRDKHDIDEDIIYSETKETLHLAFTGYWFYLIKYEKVV
>NC_013517.1|WP_049768974.1|1420585_1420948_+|hypothetical-protein
MITAELGFQNNREIFAVPGFINYPSFKGCNKLIRELKAKLVLTGKDIADEFLWEKKSKAEAEQSLSSEEKKILSLLDMEKSLDELIMETGLSAGIILAVLANLEVKDFIFEISGGRYKGR
>NC_013517.1|WP_012860791.1|1421254_1422157_+|aldo/keto-reductase
MRKIFLGKSNLKVSQLGLGCINFGSKTSESDSFELLDTYIENGGNFIDTANNYAVWAGGNGKQSEETLGKWISARKNRKDYILATKLGAYPKDINSRDFSNMQGLDSKTIKEEIEKSLNNLKTDYIDLLYLHVDDYKTPQEETMETLDEMIRKGFIREIGCSNFQTWRIESARNICEKNNYKFFSAVQQRYTYLQPVLDADFFPQVAADKSLGEYIEFYHDITMVSHTSLLKGQYLKDEITLKVYDTAENREKLQKLRAEEKNPVSWVLKYITEQFGGSVALFTTNSTKHLVENIKYFEE

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Crispr_ID: NC_013517_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_6

1817335-1817497

Orphan

Consensus_repeat	Method
GTATTAATATAACTATCTTAGAATGTAAAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_013517_6

>merge|NC_013517|6|1817335-1817497|CRISPRCasFinder
GTATTAATATAACTATCTTAGAATGTAAATATGTTATATTTTTTATCATTTTATCATCTCCTTAATGTATTAATATAACTATCTTAGAATGTAAATTAATATTACCACCTTTTTTTAGTTTTTGTGTTTCATCGTATTAATATAACTATCCTAGAACACAAAC

>NC_013517|6|6|1817335-1817497|CRISPRCasFinder
GTATTAATATAACTATCTTAGAATGTAAAT	ATGTTATATTTTTTATCATTTTATCATCTCCTTAAT
GTATTAATATAACTATCTTAGAATGTAAAT	TAATATTACCACCTTTTTTTAGTTTTTGTGTTTCATC
GTATTAATATAACTATCCTAGAACACAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012861151.1\|1808871_1809393_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012861168.1\|1824789_1825734_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NC_013517.1\|WP_012861158.1\|1815540_1816533_+\|galactose/methyl-galactoside-ABC-transporter-permease-MglC	unknown	unknown	gnl\|CDD\|181892
NC_013517.1\|WP_012861153.1\|1810383_1810596_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012861154.1\|1810621_1811194_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012861163.1\|1819596_1820466_+\|histidinol-phosphatase	unknown	unknown	gnl\|CDD\|213994
NC_013517.1\|WP_012861169.1\|1825742_1826705_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NC_013517.1\|WP_012861160.1\|1817661_1818348_+\|methyltransferase	unknown	unknown	gnl\|CDD\|226608
NC_013517.1\|WP_012861166.1\|1822896_1823826_+\|tRNA-dihydrouridine-synthase	unknown	unknown	gnl\|CDD\|223120
NC_013517.1\|WP_012861167.1\|1823925_1824777_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NC_013517.1\|WP_012861157.1\|1814008_1815523_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_013517.1\|WP_012861156.1\|1812877_1813939_+\|galactose-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380481
NC_013517.1\|WP_012861155.1\|1811678_1812548_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NC_013517.1\|WP_012861162.1\|1818962_1819508_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012861164.1\|1820743_1821346_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_013517.1\|WP_012861159.1\|1816753_1816987_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012861165.1\|1822055_1822868_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012861152.1\|1809427_1810282_+\|tRNA-2-thiocytidine(32)-synthetase-TtcA	unknown	unknown	gnl\|CDD\|236737
NC_013517.1\|WP_012861161.1\|1818376_1818943_+\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|223340
NC_013517.1\|WP_012861150.1\|1807909_1808743_+\|XdhC-family-protein	unknown	unknown	gnl\|CDD\|224886

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012861158.1\|1815540_1816533_+\|galactose/methyl-galactoside-ABC-transporter-permease-MglC	gnl\|CDD\|181892	PRK09478, mglC, galactose/methyl galactoside ABC transporter permease MglC.	4.06735e-153
NC_013517.1\|WP_012861163.1\|1819596_1820466_+\|histidinol-phosphatase	gnl\|CDD\|213994	cd12110, PHP_HisPPase_Hisj_like, Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like. Bacillus subtilis YtvP HisJ has strong histidinol phosphate phosphatase (HisPPase) activity. The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. HisPPase catalyzes the eighth step of histidine biosynthesis, in which L-histidinol phosphate undergoes dephosphorylation to produce histidinol. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. The PHP domain of HisPPase is structurally homologous to other members of the PHP family that have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel.	7.29883e-67
NC_013517.1\|WP_012861169.1\|1825742_1826705_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NC_013517.1\|WP_012861160.1\|1817661_1818348_+\|methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	1.19068e-71
NC_013517.1\|WP_012861166.1\|1822896_1823826_+\|tRNA-dihydrouridine-synthase	gnl\|CDD\|223120	COG0042, COG0042, tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis].	6.873e-80
NC_013517.1\|WP_012861167.1\|1823925_1824777_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	1.24684e-149
NC_013517.1\|WP_012861157.1\|1814008_1815523_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_013517.1\|WP_012861156.1\|1812877_1813939_+\|galactose-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380481	cd01539, PBP1_GGBP, periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species. Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species. GGBP is a member of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic GGBP is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	3.92549e-147
NC_013517.1\|WP_012861155.1\|1811678_1812548_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	9.04785e-79
NC_013517.1\|WP_012861164.1\|1820743_1821346_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.45525e-16
NC_013517.1\|WP_012861168.1\|1824789_1825734_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NC_013517.1\|WP_012861152.1\|1809427_1810282_+\|tRNA-2-thiocytidine(32)-synthetase-TtcA	gnl\|CDD\|236737	PRK10696, PRK10696, tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional.	5.72993e-60
NC_013517.1\|WP_012861161.1\|1818376_1818943_+\|dihydrofolate-reductase	gnl\|CDD\|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	3.81487e-32
NC_013517.1\|WP_012861150.1\|1807909_1808743_+\|XdhC-family-protein	gnl\|CDD\|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	1.11493e-46

>NC_013517.1|WP_012861159.1|1816753_1816987_-|hypothetical-protein
MRKILFLLILAGCTAFSDCTAKSEIAVKKLAAESKNAGVEKAYYTFAGIMPEVPYLYLYKFNMETPLKSFSIRFWEM
>NC_013517.1|WP_012861158.1|1815540_1816533_+|galactose/methyl-galactoside-ABC-transporter-permease-MglC
MDQTFQINKMKNFFAKNAIYMVLVVLVLIIGMLNKNFLQINNLTNVLMIASVRIIIALGVGGILITKGTDLSSGRTVGLTACVAASLMQRADYADKMYKNLPQLPIIAAIIAAVIVGMVIGLINGSVVSFLKVPPFIATLGTMVIVYGASSMYTKAKPIGGLRDDFTNLATGKNVLIPNIIFIAIIIMIMIWFLLNKTVFGKNIYAIGGNPIAAEVSGVKVEANLLKIYILAGALYGLAGTLLAARTGGATNNYGLMYELDAIAAATIGGVSTSGGIGKVSGIITGVLIFEVLNNGLVILGVDTNAQNIVKGIIIITAVALDIRKYLAKK
>NC_013517.1|WP_012861157.1|1814008_1815523_+|sugar-ABC-transporter-ATP-binding-protein
MENNDVLEMLEITKEFPGVKALDSVTLKVKEGTVHSLMGENGAGKSTLMKCLFGIYALDSGKILFRGEEVNFKNPKEALENGISMIHQELSPVPFRNIIDNIWLGRFKTKRLLGLKVVDEKYLYAETEKLLKKLQLDVSPKTEMKDLSVSQMQMVEIAKAISYNAKVIVMDEPTSSLTENEVDKLFEIIKQLKSEGVSIIYISHKMEEILQISDEVSIMRDGKYIGTWAAKELTTDIIISKMVGRELNERFPEKNNVPEEEDILRVENLTSISDKSFTDVSFNLKKGEILGLGGLVGAQRTELVEAIFGLRKIKSGKIFLNNKEININNPSEAIKNKMALVTEERRATGIFEVLSVKDNILITTYTDLIKYHVAVDDKLGKVITKESISNLKIKTPDEKTQIRNLSGGNQQKVVFARWLLSSPDILILDEPTRGIDVGAKFEIYNIIIDLAQKGKSIILITSEMSELLGLSDRIVVMCEGKKSGILDKKEANQEKIMELATKYM
>NC_013517.1|WP_012861156.1|1812877_1813939_+|galactose-ABC-transporter-substrate-binding-protein
MKKFRWTMILSIIMLLISCGNGGEKPAAGGEAPAGGEAKKEIKIGVALYKFDDTFISSVKDAINEISDEKSKETGEKITINAVDGQGQQATQNDQVDTFITQGYDVIAVNMVDRTAASVIIQKAQAAGIPVVFFNREPVAEDMAKWDQLYYVGAKAEESGTIQGEVAADYFKANPDADKNKDGKIQYVILEGEPGHQDALLRTEYSIKALEAAGFQVDKLASDTALWQRANGQEKMAAWISAFGDKIELVLANNDDMALGAIEALKAAGYLSDGKFIPVIGVDATAPAKDSLKAGLLYGTVLNDARGQGKGIFDIAYALAKKENPAEKVQGITDGKYLWIPYQKVTKENVDKF
>NC_013517.1|WP_012861155.1|1811678_1812548_+|cation-transporter
MHNHKHFHEREEKSDTKNIKIVFFMNLIFMIVEIIGGFLTNSMAVMSDAVHDFGDCVTLAMNWFLEEYSVKQDDEKYTYGYRRYSLVGVVINTVVLVTGSVLIITEALKRISHPQKLESGGMIALAVAGVIVNSLAVLRLRKGKKLTERAVMLHLMEDVLGWAAVLIAGIFIKLFELYIIDTILSIVIAAFVLSNVIKNFKETAGIFLQAVPSGYNIIKLRKKMIRVKGILDIHDIHLWSLDGINNIISFHCVVPYDILTDEVLKIKYRLKKYLKYIGINHITIEIEYD
>NC_013517.1|WP_012861154.1|1810621_1811194_-|hypothetical-protein
MKSKYIKIGLLILLLLSLFSCNNSKKEIRVIVDKYYSSLKKGDLDQMLNLFSFDIKLSYDNLYQQNPELKTFTSDTLKIVGSSFDYEIEKVKIKDNKAVVTIKETGLDKEMLDKKIKELTSKESFIPSNNNDFEKAKKEFVDYQMNILSQAVKEVKEKKSSATTLTLEKEKSGWVITTKNLLRVIPKDEI
>NC_013517.1|WP_012861153.1|1810383_1810596_+|hypothetical-protein
MQFDSFSEPEYKGNNICDTVIFDTDGGITDTLSLKISAGTVYLTNEQNGKKIKIYQNDICKMCGEIKIYT
>NC_013517.1|WP_012861152.1|1809427_1810282_+|tRNA-2-thiocytidine(32)-synthetase-TtcA
MNSLSNISCEAVLPVTELKSTDEIERSIQKKYRKYLWSPFIKAAKEFSLVEDGDRIAVAISGGKDSLLLAKLLQELQRASRTEFELVFISMNPGFNSENLENLKKNLDHLRIPCEIYDDNIFEIAEKMAKDYPCYMCAKMRRGSLYTKAVSLGCNKLALGHHMDDVAETVLMSMFQMSKYETMLPRLKADNFDIELIRPLYYVEEKDIIKFTANNGILAMNCGCTVAAGKTSSKRRETKELIRELAKSNPNIKKNILNSTKNVNLEKILGWKIGGKKYGYLDKY
>NC_013517.1|WP_012861151.1|1808871_1809393_+|hypothetical-protein
MKKVIYILLFLLLLIIYGIVEYYSYSNVYTGNFCVTKQKIEEQAEKYEKLRIDENGNFSRSYDELRKAFFDDIVQNGKYRMYIADINRKVYVNNEETLEGQGFPGNIMEVSTKNTENGQRLYMIVEDNESGKEVFRIKRYQIYPYKELLNMSYTGSASVVVQFRCELERGSKK
>NC_013517.1|WP_012861150.1|1807909_1808743_+|XdhC-family-protein
MEELILKKILENLENHKKVALVTLTDVGGSTPRDTGSLMLVWENGETYGSIGGGKVEYFVTGEAVEALKQNTDRNFEHSLTPDGDLEMQCGGTVKGFIKIFRPNEKIVIAGGGHVGEKVLELAKFLGFTCEVIDDREDYIDKPSLQKADKITVGFYKDIVKDAAIDENTYVVIATKSHITDLEFVKEVLKTKARYIGTIGSRKKQIFLREELLQDGFSAEDIKRIYGPVGINISNQMPEEIAVSILAEILMVKNGGTTEHRKLEDSIVDNIVQKHLK
>NC_013517.1|WP_012861160.1|1817661_1818348_+|methyltransferase
MKKTGEEVLGSINKLKIIQRNDHQNYTLDSRLLSDFCRINRHVKKILDIGTGNAILPLLLSQKSKAEITGIEILKISAELAVKNIELNNLSDRIKIIEGDIRKWADYFRPAEFDQIITNPPFFKYDGNDDQINDLEQLSVARHEYNIKLEEIIQISSVLLKNRAYFTMVHRSERLAEILELLVKYGLEPKRIRFCHTKKDAPAKILLIEAVKGAKKSLVIESPLILSD
>NC_013517.1|WP_012861161.1|1818376_1818943_+|dihydrofolate-reductase
MGSEPNVILYTAMSLDGYIAKEDGSVDWLEDTGEGVEGTYLKFYSSIDTIIMGRKTYDQILTFGEWVYKGKDTYVLTSDISRVPEKPNIEFRNDEIEDLTTELKQKSKSNIWLLGGAETVNAFLEKKLIDEYRIAIVPVILGTGIPLFTSGAEENLDFKQVTEYDGIVELKYEKKKMKIANFEINNNK
>NC_013517.1|WP_012861162.1|1818962_1819508_+|hypothetical-protein
MKKVILILTLVIGLLGFSEGNVKTFDNLNTAVSEYGKVMQEVLNYASREDFSSTGDNLAGFLKNSGNTALEKKWDGIRNKLAEPYEIKANTPKMEGSSKAVVNYDVYGYDEGKIAEMIDQNVEQFVQEDENGEITIDMEKYILSVEDFLNKAKKVKVAATQIEFEKVAGKWMLKEKGAFEN
>NC_013517.1|WP_012861163.1|1819596_1820466_+|histidinol-phosphatase
MLADYHMHFEYGSYDEEWVKGFFESAYEKGVTELGITEHSHGFKEFKDLYYDELILDNSEIGEFQKKWLGNVKSKFVHTLDEYRDFINSLKQKGYPVKFGIEVCNFRNQERVSEILSKYDFDYIIVSIHFIKGWGFDFSALKDIFEKQSVYNIWEDYVREIENVAQSGLYDILGHPFNLRLFNNFPEKNVDDLLEKTAEALKENNMAIDINTGTYYRYPINEISPYEDFMKLVKKYEIPVILSSDAHEPGHAGFMIKEAAEYALSFGIDKFLRFDKKKRISEMICLKNK
>NC_013517.1|WP_012861164.1|1820743_1821346_+|TetR/AcrR-family-transcriptional-regulator
MARRAGFQINREDIIRAAIKQISKYGFSNFTLSNLSKELNITKAALYWHFKSKNDILMEVLKYIELEYISKISEICDDKSLSASEKLKNYLTFVYEKSESDVHLCVIPSKLLGEFLHKDSEFHEEIREIYANYKESIAKILIDGIIEGDFKKNTSPIDHARFIVGSIDGILQQYISDHTQVHKVFTTGEKFSEYVMTLFV
>NC_013517.1|WP_012861165.1|1822055_1822868_+|hypothetical-protein
MEEIIERIQDEIFLIFMLLLSFSVFMYIITEKLSFVSMFLCMTVSLAAVNKEAYLLDALGFFLLGIISFVIMLDIDMWIEMGIMEMNLRQKIVRMICMAVLAVPLFRILHTYSFINNFTLNPRSVILCFITGVFAILVLGIVPRYMLVFLSRLKPNKKITSFFIIKAMRYRMFHGMIQSKLYVRDGVGEYKFEVSNRAYKMLRNKTYVKIQMQEGLFGTYYVKNNFLGRDRLRTLKEDIPRFLTAFAVIIILMGLSIAFCHVINNYAWVG
>NC_013517.1|WP_012861166.1|1822896_1823826_+|tRNA-dihydrouridine-synthase
MQIITAPMAGITDYSFRKILYEFSPDIIFTEMVDVNALKYSNQRTQDEILRKAGNEAVQIFGNKNEDFLEAVKLLIERGFDHIDINLGCPVKKIIRAGKGSALLLESDFVKELLLKLKKEFRNDIKLSMKIRTGYKNFSDPEYYVKLAEEYGLFQICIHGRTQEQLYSGQADWNIIKKMKQKHKNVKIIGNGDLTDLKTIKEKTDSAKPDGIMLARGLLGNPWLLKEAKDYFKTGVFHESEVGREEIKNTLIKHINYCIEDKGEIRANLDMRKHIFWYLKEFENIEKIKNDIIKTKTIKDVLKYIVNNV
>NC_013517.1|WP_012861167.1|1823925_1824777_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MGIFSAKKTKNQYAKVTTKSKLTLDITESSQWKKCSKCNEIIYNEDLKNNLNVCPKCGNYFPLNAFERIELLIDERTFEEQDITLNSKDFLNFPMYKEKLEESIDKSRMLDAVISGSGKINGIGVNIAVMDFNFMGGSMGSVVGEKVTRILERSLEEKIPAIVVSSSGGARMQEGIVSLMQMAKTSGAVKRLNEAGIPFISVPVNPTTGGVTASFAMLGDVIITEPDALIGFAGPRVIEQTINQKLPKGFQRAEFLLEHGMIDIISERKDLKETIFRVLEKLV
>NC_013517.1|WP_012861168.1|1824789_1825734_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MSIEAEMRDLESKIEELKKFSKEQKIDFSKQIEELEEVLKEKIKEYSKTEIDAWGRTQISRNPKRPYTMDYIERIADDFVELHGDRLSKDDHAIVGGLASIDGNGIMIIGHQKGRDMEANIYRNFGMASPEGYRKALRLMRMAERFEVPILTFIDTSGAYPGLEAEEKGQAEAIAKNLAEMFGLKVPVIAVVIGEGGSGGALGIGVADSVLMMENSIYSVISPEGCASILFKDSKKAPEAARSLRIDAFSLKSLGVIDGIIKEPIGGAHRDYDETAKNLKNAVVKEFRKLEKIEIEKLLENRYNKFRRIGEFFE
>NC_013517.1|WP_012861169.1|1825742_1826705_+|6-phosphofructokinase
MKKIGILTSGGDSPGMNTAIRAVTKMAMNYNCEMYGIKRGYKGMLNDEIFKLNPLDVSGIADRGGTILLSARLPEFKQPEVRAKAAANLKRHGIEGLVVIGGDGSYRGADLLFREHGIKVVGIPGTIDNDIAGTDYTIGYDTTLNIILDAVSRIRDTANSHERTYLLEVMGRDCGDLALYSAMAGGANGVLIPEVNRSIDELAEDIKERRSQRKLSDIIIVAEGVGHVFDIAKELKEKINTEIRVTVLGHIQRGGSPTAFDRVLATRMGARAFELLMEGESGIMVGMENNKMVTHAISYAWENKTNISLDDYNLTHLLSI

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Crispr_ID: NC_013517_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_7

2840148-2840310

Orphan

Consensus_repeat	Method
ATTTACATTCTAAGATAGTTATATTAATAG	CRISPRCasFinder
CTATTAATATAACTATCTTAGAATGTAAA	PILER-CR

2 spacers

The CRISPR arrays of NC_013517_7

>merge|NC_013517|7|2840148-2840310|CRISPRCasFinder,PILER-CR
TTTTTTGCTCTAAGATAGTTATATTAATAGAAAACTCAATCAAAATAGGGTGTCAAAAGTACACTCATTTACATTCTAAGATAGTTATATTAATAGCTGTTAAATCCATGTTATAATATATTATCTTTTTGAAATTTACATTCTAAGATAGTTATATTAATAG

>NC_013517|7|7|2840148-2840310|CRISPRCasFinder
TTTTTTGCTCTAAGATAGTTATATTAATAG	AAAACTCAATCAAAATAGGGTGTCAAAAGTACACTC
ATTTACATTCTAAGATAGTTATATTAATAG	CTGTTAAATCCATGTTATAATATATTATCTTTTTGAA
ATTTACATTCTAAGATAGTTATATTAATAG

>NC_013517|7|2|2840156-2840310|PILER-CR
TCTAAGATAGTTATATTAATAGAAAACTC	AATCAAAATAGGGTGTCAAAAGTACACTCATTTACAT
TCTAAGATAGTTATATTAATAGCTGTTAA	ATCCATGTTATAATATATTATCTTTTTGAAATTTACAT
TCTAAGATAGTTATATTAATAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012862101.1\|2828575_2829199_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NC_013517.1\|WP_012862105.1\|2832191_2833007_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	unknown	unknown	gnl\|CDD\|99814
NC_013517.1\|WP_115388794.1\|2841188_2841674_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239489
NC_013517.1\|WP_012862103.1\|2830476_2831184_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NC_013517.1\|WP_012862106.1\|2833029_2833479_-\|aspartate-carbamoyltransferase-regulatory-subunit	unknown	unknown	gnl\|CDD\|234859
NC_013517.1\|WP_012862102.1\|2829191_2830448_-\|dihydroorotase-family-protein	unknown	unknown	gnl\|CDD\|223122
NC_013517.1\|WP_012862117.1\|2844876_2845875_-\|toxin-antitoxin-system-YwqK-family-antitoxin	unknown	unknown	gnl\|CDD\|225405
NC_013517.1\|WP_012862116.1\|2843658_2844852_-\|3-deoxy-D-manno-octulosonic-acid-transferase	unknown	unknown	gnl\|CDD\|224436
NC_013517.1\|WP_041310003.1\|2831200_2832154_-\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235982
NC_013517.1\|WP_041310840.1\|2833486_2834392_-\|aspartate-carbamoyltransferase	unknown	unknown	gnl\|CDD\|223614
NC_013517.1\|WP_086015028.1\|2842944_2843568_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NC_013517.1\|WP_012862109.1\|2837774_2838830_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NC_013517.1\|WP_012862108.1\|2834486_2837696_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NC_013517.1\|WP_012862121.1\|2850073_2850754_+\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|223710
NC_013517.1\|WP_012862118.1\|2846081_2846555_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NC_013517.1\|WP_012862119.1\|2846554_2847427_-\|xanthine-dehydrogenase-FAD-binding-subunit-XdhB	unknown	unknown	gnl\|CDD\|182175
NC_013517.1\|WP_012862120.1\|2847440_2849732_-\|xanthine-dehydrogenase-molybdenum-binding-subunit-XdhA	unknown	unknown	gnl\|CDD\|236637
NC_013517.1\|WP_012862114.1\|2841957_2842914_-\|L-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|133427
NC_013517.1\|WP_012862112.1\|2840597_2840843_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012862111.1\|2839260_2839836_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012862101.1\|2828575_2829199_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	4.56257e-62
NC_013517.1\|WP_012862105.1\|2832191_2833007_-\|dihydroorotate-dehydrogenase-electron-transfer-subunit	gnl\|CDD\|99814	cd06218, DHOD_e_trans, FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+. In L. lactis, DHOD B (encoded by pyrDa) is co-expressed with pyrK and both gene products are required for full activity, as well as 3 cofactors: FMN, FAD, and an [2Fe-2S] cluster.	2.15204e-96
NC_013517.1\|WP_012862108.1\|2834486_2837696_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NC_013517.1\|WP_012862103.1\|2830476_2831184_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	1.87623e-106
NC_013517.1\|WP_012862106.1\|2833029_2833479_-\|aspartate-carbamoyltransferase-regulatory-subunit	gnl\|CDD\|234859	PRK00893, PRK00893, aspartate carbamoyltransferase regulatory subunit; Reviewed.	1.30463e-55
NC_013517.1\|WP_012862102.1\|2829191_2830448_-\|dihydroorotase-family-protein	gnl\|CDD\|223122	COG0044, PyrC, Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism].	1.89423e-132
NC_013517.1\|WP_012862117.1\|2844876_2845875_-\|toxin-antitoxin-system-YwqK-family-antitoxin	gnl\|CDD\|225405	COG2849, COG2849, Uncharacterized protein conserved in bacteria [Function unknown].	4.50758e-20
NC_013517.1\|WP_012862116.1\|2843658_2844852_-\|3-deoxy-D-manno-octulosonic-acid-transferase	gnl\|CDD\|224436	COG1519, KdtA, 3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane].	1.90783e-89
NC_013517.1\|WP_041310003.1\|2831200_2832154_-\|dihydroorotate-dehydrogenase	gnl\|CDD\|235982	PRK07259, PRK07259, dihydroorotate dehydrogenase.	1.42381e-166
NC_013517.1\|WP_041310840.1\|2833486_2834392_-\|aspartate-carbamoyltransferase	gnl\|CDD\|223614	COG0540, PyrB, Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism].	4.80742e-144
NC_013517.1\|WP_086015028.1\|2842944_2843568_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	2.39821e-52
NC_013517.1\|WP_115388794.1\|2841188_2841674_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239489	cd03395, PAP2_like_4, PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	8.48197e-27
NC_013517.1\|WP_012862121.1\|2850073_2850754_+\|HAD-family-phosphatase	gnl\|CDD\|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.56202e-36
NC_013517.1\|WP_012862118.1\|2846081_2846555_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	2.56163e-69
NC_013517.1\|WP_012862119.1\|2846554_2847427_-\|xanthine-dehydrogenase-FAD-binding-subunit-XdhB	gnl\|CDD\|182175	PRK09971, PRK09971, xanthine dehydrogenase subunit XdhB; Provisional.	6.2743e-166
NC_013517.1\|WP_012862120.1\|2847440_2849732_-\|xanthine-dehydrogenase-molybdenum-binding-subunit-XdhA	gnl\|CDD\|236637	PRK09970, PRK09970, xanthine dehydrogenase subunit XdhA; Provisional.	0
NC_013517.1\|WP_012862114.1\|2841957_2842914_-\|L-lactate-dehydrogenase	gnl\|CDD\|133427	cd05291, HicDH_like, L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases. L-2-hydroxyisocapronate dehydrogenase (HicDH) catalyzes the conversion of a variety of 2-oxo carboxylic acids with medium-sized aliphatic or aromatic side chains. This subfamily is composed of HicDHs and some bacterial L-lactate dehydrogenases (LDH). LDHs catalyze the last step of glycolysis in which pyruvate is converted to L-lactate. Bacterial LDHs can be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. Members of this subfamily with known structures such as the HicDH of Lactobacillus confusus, the non-allosteric LDH of Lactobacillus pentosus, and the allosteric LDH of Bacillus stearothermophilus, show that they exist as homotetramers. The HicDH-like subfamily is part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	2.39027e-155
NC_013517.1\|WP_012862109.1\|2837774_2838830_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NC_013517.1\|WP_012862111.1\|2839260_2839836_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	3.22592e-24

>NC_013517.1|WP_012862111.1|2839260_2839836_-|phosphatase-PAP2-family-protein
MLNIMDQTAVNAVKLIQNPLLDKIMVFFTSLGDNGIIWIILMIVLLSGKKTRNKGVVLLITVITVFILTNYLKEEFHRVRPYEYMNFIPKVKTSGTSSFPSAHSAVAFAVFGVYYFYNLRYKYVIGVIALIIAVSRFYLEVHYLSDVLAGIALGLTVSYILFHVNEIILKSVKINNVYNILKRFFTGESQQ
>NC_013517.1|WP_012862109.1|2837774_2838830_-|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit
MKAKLILENGMIFHGEAFGYLEETVGELVFTTVMTGYQEVLTDPSYHGQIVVMTYPLIGNYGINLEDMQSDRVRVKGFIIKEDAKLPNNFRCEITLEAYLKQNKVMGLKNIDTRHLTRIIRDTGTKKAVITTRDLSQEELGNIFFSFSNSDAVKQVTRKDILKIEGSKEKIAIIDFGIKKHIIESFAKRNCDIRVFPAYTDYETIMEYNPDALFLSNGPGDPEDLPEAIELVKKVIGKKPVIGICLGHQIAALAMGGKTAKMRFGHRGGNHPVKDIEKNKIYISSQNHGYKVTELPEGTVLSHVNLNDNSIEGMKNKELKVYTVQFHPEASPGPEETAYIFDDFLNMIREG
>NC_013517.1|WP_012862108.1|2834486_2837696_-|carbamoyl-phosphate-synthase-large-subunit
MKNDSIKKVLVIGSGPIVIGQAAEFDYSGTQACEALREEGIEVVLINSNPATIMTDSKTADKIYIEPMNIQTIEKIIAREKPDSLLPGMGGQTALNLAVELKDAGILEKYNVNIIGTSIESIKKGEDRELFRESMMKIGEPVIDSSIVTNLEDGQDFAAKIGYPVVVRPAYTLGGSGGGIAGSPEELKDILLKGLQLSRVGQVLVEKSILGWKEIEYEVIRDKDGNCITVCNMENIDPVGIHTGDSIVTAPSQTLSDKEYQMLRTSSIKIINEIGIVGGCNVQFALNPLSFEYAIIEINPRVSRSSALASKATGYPIARVAAKLSLGYTLDEVKNEVTGETFACHEPAIDYVVVKIPKWPFDKFQKVDRKLGTKMMATGEIMAIGNNFESAFLKGIRSLEINRDNLMHPASAKRSLEELKERIQKPDDERIFDLAEMLRRGYVKRQLARLTGIDIFFIEKIEWIVKQEEQLKDMTFNDLNMEYLKKLKRKGFSDKGIAELMGISTEDIRLKRKEYGIKPVYKMVDTCAAEFEAVSPYYYSTYDKYDEVVVSDRRKIIVIGSGPIRIGQGIEFDYCTVHNIAALKKMGIESIIINNNPETVSTDFSTADKLYFEPLTAEDVLEIVEKEKPEGVILQFGGQTAIKLAGELTKKGIKIIGTSFEKIDEAEDREKFDKLTDRLKIKKPEGKAVWTAEEGVKTAEAIEYPVLVRPSYVLGGQGMEICYDECNLRKYLESAFYRDSENPVLIDKYLNGAEIEVDAICDGEDILIPSIMEHLERAGVHSGDSITVCPTQNVSEDIKKKVEEITKVLARELEILGMINIQFIAYKEELYIIEVNPRSSRTVPYVSKITGIPVIELATRAALGEKLKDMGYGTGVYKEPKLIAVKVPVFSTEKIEGIEISLGPEMKSTGEVLGVGKTYEEAVYKGLLAADKKYPESGKKALVTLNDNDKAEFLPLAKKLAKQNYKLSATEGTYKFLKEHGIESEVINKISGDSPNILDKLKNREIDILINTPTKANDSQRDGFKIRRTAVEYGIEVLTSLDTLNAVLGILEKGLHKKETEIYEMNSQK
>NC_013517.1|WP_041310840.1|2833486_2834392_-|aspartate-carbamoyltransferase
MRDFSKEEILHILKISEEVENDENKGELLKGKIISTLFFEPSTRTRLSFQSAAQRLGAQVLGFDSPDGTSVKKGETLSDTIKMAESYSDLIVIRHPLDGSARVAAEASKVPVLNAGDGVNQHPSQTLLDLYTILKEKKTLDNMKIAFVGDLKYGRTVHSLVKAISHFNPKIYFIAPEILRIPEYILDDLEELGIEYEVLEDFRECLADIDVFYMTRVQRERFPDEEEYEKVKGIYVISKENIIGKCKDDMIILHPLPRVDEINTDLDDTKHALYFKQAKNGVPVRQAMMLTALGIKEKIEG
>NC_013517.1|WP_012862106.1|2833029_2833479_-|aspartate-carbamoyltransferase-regulatory-subunit
MELQISAIKNGTVIDHLPTDTALKVVEILDLKNFRETVTVAFNLTSNSLGKKGIVKVACRTLTKEELEKISLIAPGATINIIEDFKVKEKKEVPEPKEINGIVKCNNSRCITNSEKVEIKFLNESDSHGRKYRCIYCEKVIKYTDIILK
>NC_013517.1|WP_012862105.1|2832191_2833007_-|dihydroorotate-dehydrogenase-electron-transfer-subunit
MKNFLNDVKILENREIGKDNYLLRVKMNDECIVPEAGQFYLLKCRDGAKILKRAISLHYIDEDERILEFVYKITGKGTKEISEYKKDEYINIQGPLGKGFGTGIKDKTAVVIGGGIGLAPLKQLIKNIKESNRIVFIAGGRDMEALKILENFDSENIDLKICSDDGSIGKKAFVTELLESYLKNGAADIIYTCGPHIMMEKIAEIAEKNNVQCEVSMEERMACGVKACVGCSIKTTEGMKKVCHDGPVFNSKIIIKSLSRMTEEECSAKCI
>NC_013517.1|WP_041310003.1|2831200_2832154_-|dihydroorotate-dehydrogenase
MNFLKMNFAGLDLENPIMTASGCFGFGLEYKDYFDPNELGAVLIKGLTPEPREGNYGIRIAETPAGMLNSVGLENPGIDYFERETAPLLERELKVPVIANINGKILEEYIEIAERAEAIDVIKAIELNISCPNVKDGGMAFGANPDMAAKVTREVRRVTKKPLIVKLSPNVTDIAGIAKLVEAEGADALSLINTLLGMSIDINKKKPLLGNIFGGLSGPAVKPVALRMVYQVSNAVSIPLLGMGGISTAEDALEFFMAGASAISVGTGFFQNPLAAVEIKQGLINYCTENNLSNINEIVAYAHTDDGKAYRKRIFSK
>NC_013517.1|WP_012862103.1|2830476_2831184_-|orotidine-5'-phosphate-decarboxylase
MKARKKVITALDYKNMDDVKNLVELLGDEIEYYKAGLEIFLNTGGEIVDYLHSLNKKIFLDLKFHDINNTTKMACEFAARKGVFIFNIHASCGTETMYEISKMLKDMNSKSLCIAVTVLTSMTEEKMQEIFMTDASLDNMVMNMAELTGKSGLHGVVCSAWEAAKVKERCGENFVTVCPGVRPAWSASDDQKRIMTPAEAVKNGADYLVIGRPITKADDPKKAAMRILEEIEAVL
>NC_013517.1|WP_012862102.1|2829191_2830448_-|dihydroorotase-family-protein
MLLRNGTLVNGEKADILIINGKIHLIKKEIEIKEAGRIFTEITGKKLEEIDLKYRYIMPGVIDVHTHMRDPGFTQKEDFISGSKACAKAGITTFIDMPNTNPATITEEALEMKRKSAGEKSAVNYGFHFGGSSDNNSQEIGKAKGVLSTKVFLNVSTGKMLVEDDKVLESIVKAANFLTVHAEGEMINKALEFNKKFGKGLYICHVSSREEMEIIEKAKADNIFNNENHPIFAEVTPHHLFLDEEMKDSDEEKKMLYRMKPELKTKSDREYLWQSIENGTVDTIGTDHAPHLKSEKMEKITFGMPGVETSLALMLTAYNRGKISLVKIQELMCENPARIFGIKNKGVLKEGYDADIIAVDTEQEWLVKKEELLSKCGWSPYEGWKLKGKNILTIVNGNIVYKDGKIFENKGKEVEIDE
>NC_013517.1|WP_012862101.1|2828575_2829199_-|orotate-phosphoribosyltransferase
MNKKEQTAKILFDLKAVKINVKEPFTFSSGIKSPIYCDNRVILGYPEAREQIVQGFLDIIDTENTDVIAGVATAGISWAAFIAEKLGKPMAYVRSKPKGHGVGRQIEGAETAGKRVAVIEDLISTGGSSINAAEVLRNSGADSVEVKAIFSYNFKSAFENFEKINCKWDIISDFDILIELLKNEKYLNETEAKTALEWNKNPESWGK
>NC_013517.1|WP_012862112.1|2840597_2840843_-|hypothetical-protein
MEYTSNSKTLLGKLKEGNPLALRRMYAQYRQNIYFPEIDIYKSLYKSDVEILFIYLRKGFYESEIIEALNEYNDFIKQLRR
>NC_013517.1|WP_115388794.1|2841188_2841674_-|phosphatase-PAP2-family-protein
MIFFSGIGNLGIVWIVLALVLVMRRKTRNYGIILLLALLITAILGEGILKNIIKRNRPFIVLNDLKLLIPPPGSYSFPSGHTASSFTAFGVFYFLNLRYKWPVFFIAFFIAFSRIYLGVHYFTDIIGGIILGMGVAYMVCSYYKKNSDRINSNKIIRKLFN
>NC_013517.1|WP_012862114.1|2841957_2842914_-|L-lactate-dehydrogenase
MKIKSRKVAVIGVGNVGSHVAFSLVTRGITDELILIDIKEDKVKSEMLDLKDSLANLNSNVTIKIQNYSELKDAEIVVIAAGPLPRFEQTRLDTLDDGIKIIDDIMPKILESGFSGIFLVITNPCDVITHYVLEKSGFPKSRVIGTGTSLDSARFRRITGDILGIDPKSVSGYSLGEHGDSQMIPWSHIYVGGKPFKQYIESKEELKNTDLDKILKDTSYAGWEVLLGKGATCFGIGTAASALIKSIFNNEYSVHPVSVFLDGEYELKNVCLSVPVILGNKGVEEIIELKLTEEEQKQLNRSAEVIKTYIGKINKKII
>NC_013517.1|WP_086015028.1|2842944_2843568_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MEKMTEYPEYIIYDEEITDSKKNKWNEYFGNDNPVYLEIGCGSGNFTASNAQKFPGKNYIALELRFKRLVMAAVKSKKRELKNIVFLRKRGEKLLDFLGKDEISGLYINFPDPWTGSEHKRLINKELFDRLDIIMKPSGKLFFKTDHEGYYYDTLELVKGLAKYEIVFHTDDLYNTEKVKDNIQTEFEQMFLSKHNMNIKYIEIVKK
>NC_013517.1|WP_012862116.1|2843658_2844852_-|3-deoxy-D-manno-octulosonic-acid-transferase
MLFIYNIVRFFLYPFLFIAAIFKKKIRAFFYKRIRVEKIKRDKYYWIHLSSVGEMNLAEKLIENILDRNKKIYLTVMTDTGMELFRKRYSGNPNIKGAYFPLDDYFLIKKTVNMLDIEKLIIIETEIWPNLYGIVSEKSEVIVVNGRISDKTFDKYKKIKGMISATLNKCSKILVQSNLDLQRYKELGVREEILKVYPNLKYSIDYPVLDTEQKEELEERIKINGRKLITAGSTREGEEKILIDIFKKINEAEKYQMVLVPRHIQRTEEVAALCEGLDFSLYSENKKTEIIIVDKMGILREMYQISDLVFVGGTFVEIGGHSILEPLYYGKVPIIGKYYSNIKDVAENAKPLNLVNIAETESELEAFFLDSDNSKNRETSEFFKKYNKIDEIIKEIL
>NC_013517.1|WP_012862117.1|2844876_2845875_-|toxin-antitoxin-system-YwqK-family-antitoxin
MILKKHYLEKLTVIFAIKEDYDHREVYYYENRRFEGELHMYYDDKKQQLESIERFKNGKKSGVQEKYYENGILKASENYIDGLEEGKYEEYFEDGEVKLNCFYIEGKRNGKLQEFYKEGGLKEENNYYYGNLDGISSKFHKNGKLSHTGMYKEDLKTGIWNFYDENENLRRKEIWKDGKLNGQRIELENENVQMSSNYVDGELDGEFIIYGKNKNIIHLIHYEKGRKNGKEILYNEAGKVKKETDYKNNMKYGTEKEYSDDGEILLLEANYVEGLLHGSYVSFHEDGNRKFEGRAMDGKFHGEAYFYDKNGDLESEVIYEHGEVARKIEHKK
>NC_013517.1|WP_012862118.1|2846081_2846555_-|(2Fe-2S)-binding-protein
MVKSITFTVNGKEYNINVDIRKSLLEVLREELNYTGAKQGCAVGECGACTVIIDGVTADSCIYLAVWADGKNIKTIEGVSDRGGNLSDIQESYIDAGAVQCGFCTPGLILSTEVLLENNPEPSKDEIRRGLSGNLCRCTGYQKIIDAVEKTVEKRKG
>NC_013517.1|WP_012862119.1|2846554_2847427_-|xanthine-dehydrogenase-FAD-binding-subunit-XdhB
MYDIKTYTEVKTVQEAVELLADNENAQIIAGGTDVLIKSRERKNGYVGRDLIGITRIPELKEIKINSSGDIIIGAAATFTEVEGNEFIIKNVKSLSDAVGSVGGPQIRNVGTVGGNICNGATSADSASTLFAYNAVLMITGKNGNKEVSIKDFYLGPGKVLLERGDILTAVKITKENYEGYKGHYIKFSPRQAMDIATLGCSVLLKENNGTIEDMRIAYGVAGPTPLRAASAEEFAKGKPINDEILNEIGKICLESARARDSWRASKAFREQLVEELPKRAVKAIIGGGR
>NC_013517.1|WP_012862120.1|2847440_2849732_-|xanthine-dehydrogenase-molybdenum-binding-subunit-XdhA
MSYKIIGQSVERWDAIAKVQGKADYTADLPKKNVLYGKILRATIAHGLVKKLDVSEALKVEGVIKVLTPDDLPDLKFPTAGHPYTLDPKLADIADRNILTKRVRLYGDEIAAVIAENELAAEKALEKIKVEYEEFPFYLSPEEALAEGAVEIHDGSKNLIASTKAVVGDLKKGLEEADHIIEGEYKTQIVQHCHMENQIAYAYKGSDQRWVCVSSTQIPHICRRILGEAFGMPWGKFRVVKPFIGGGFGNKQDVTIEPLAVAMSMAVGGEPVMVELQREESIAWTRVRHAISYKVKLGVKKDGTITALEMDAVSNNGAYASHGHSIAGKGAGILQSLYKMPNMEYNSKTVYTNTASAGAMRGYGVPQVIFAMESIIEKAAKELGIDPVELRLKNLVGPNTENPVSHVMFFSNKLKECVEEGMKNFSWDERKKQADSQKTGDFRRGVGMAVFAYATGVYPKSLEIGGCRLTLNQDGTVKLMVGATEIGQGSDTVFKQMVAETTGIPYDHIYTDMNTDTDYSPFDTGAYASRQSYVSGMAVRKAAIELKEKILDAVKKFDDIDQLHTDIVNGNIVYKHSGEVIQSVGDLALKSYYDLANGECITAEVSNNFHSNSNAMGATFADVEVDIKTGKVKILNILNVHDSGHILNPLLASGQVEGGMGMAVAYALAEELRYDEKTGAPLNNNLLDYKMPTSMDLPDMETLFVEEDDPMGPYGNKALGEPPICSPAAAIRNAVLDAIGIEVDELPIKPQKLMEILKNNGIV
>NC_013517.1|WP_012862121.1|2850073_2850754_+|HAD-family-phosphatase
MKIKGIIFDFNGTLLFDSDKHEKAWHIFIKEFCNKEISDEEFEKNIHGIVNKKALEYLYKRTLSNEEVLSLEQEKEKIYRRLVLEDTANFRLVPGAEELLDYICKENIPHTIATASEIVNLEFYIKSFSLEKWFDTEKIIYNDNTLPGKPDPAIYIKAAETIGVNPEDCLVFEDSKAGLTSAHNAGAGKIIAVASTPEEREKAEKIHWISDIISNFYDFDMNILKK

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Crispr_ID: NC_013517_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_8

3407862-3408065

Orphan

Consensus_repeat	Method
TTTTTCAAAAGATAAAAATCATATTTATTACGG	PILER-CR

2 spacers

The CRISPR arrays of NC_013517_8

>merge|NC_013517|8|3407862-3408065|PILER-CR
TTTTTCAAAAGATAAAAATAATGTATATTATGCCGGGATACTGTCCGCGGCTGATACAGAAAGCTTTGAAATTCTGAATTCACCATATGCGAGAGATAAAAATCATTTTTACTTCGGAAATATTTTTTTGAATAAAATTGACACGAAAAGTTTTAAGGTATTGAATTCTACTTTTTCAAAGGATAAAAATCATATTTATTACGG

>NC_013517|8|3|3407862-3408065|PILER-CR
TTTTTCAAAAGATAAAAATAATGTATATTATGC	CGGGATACTGTCCGCGGCTGATACAGAAAGCTTTGAAATTCTGAATTCACCATATGCGAGAGA
TAAAAATCATTTTTACTTCGGAAATATTTTTTT	GAATAAAATTGACACGAAAAGTTTTAAGGTATTGAATTCTACTTTTTCAAAGGA
TAAAAATCATATTTATTACGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012862667.1\|3403529_3406166_+\|mannosylglycerate-hydrolase	unknown	unknown	gnl\|CDD\|182093
NC_013517.1\|WP_012862666.1\|3402403_3403504_+\|PTS-fructose-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224218
NC_013517.1\|WP_012862678.1\|3416161_3416605_-\|PTS-system-fructose-subfamily-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NC_013517.1\|WP_012862665.1\|3401916_3402234_+\|PTS-fructose-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|224362
NC_013517.1\|WP_012862663.1\|3392510_3400793_-\|autotransporter-domain-containing-protein	unknown	unknown	gnl\|CDD\|377133
NC_013517.1\|WP_012862658.1\|3388658_3389642_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381313
NC_013517.1\|WP_012862668.1\|3406237_3407272_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_013517.1\|WP_012862677.1\|3415640_3416144_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|377139
NC_013517.1\|WP_012862662.1\|3391504_3392140_-\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381617
NC_013517.1\|WP_012862671.1\|3410171_3410462_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012862675.1\|3414004_3414814_-\|PTS-system-mannose/fructose/sorbose-family-transporter-subunit-IID	unknown	unknown	gnl\|CDD\|377079
NC_013517.1\|WP_012862676.1\|3414813_3415641_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|377077
NC_013517.1\|WP_012862659.1\|3389658_3390141_+\|flavodoxin	unknown	unknown	gnl\|CDD\|180850
NC_013517.1\|WP_147289491.1\|3413693_3413999_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012862660.1\|3390198_3391179_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381305
NC_013517.1\|WP_012862679.1\|3416617_3417355_-\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
NC_013517.1\|WP_012862664.1\|3401461_3401920_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|334031
NC_013517.1\|WP_012862672.1\|3410492_3411935_+\|alpha-amylase	unknown	unknown	gnl\|CDD\|236518
NC_013517.1\|WP_012862670.1\|3408569_3409595_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|182305
NC_013517.1\|WP_012862673.1\|3412007_3413528_-\|phosphoglucomutase	unknown	unknown	gnl\|CDD\|215211

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012862667.1\|3403529_3406166_+\|mannosylglycerate-hydrolase	gnl\|CDD\|182093	PRK09819, PRK09819, mannosylglycerate hydrolase.	0
NC_013517.1\|WP_012862666.1\|3402403_3403504_+\|PTS-fructose-transporter-subunit-IIC	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	9.03668e-90
NC_013517.1\|WP_012862678.1\|3416161_3416605_-\|PTS-system-fructose-subfamily-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	7.3625e-17
NC_013517.1\|WP_012862665.1\|3401916_3402234_+\|PTS-fructose-transporter-subunit-IIB	gnl\|CDD\|224362	COG1445, FrwB, Phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism].	1.99002e-35
NC_013517.1\|WP_012862663.1\|3392510_3400793_-\|autotransporter-domain-containing-protein	gnl\|CDD\|377133	pfam03797, Autotransporter, Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.	2.33688e-22
NC_013517.1\|WP_012862658.1\|3388658_3389642_+\|aldo/keto-reductase	gnl\|CDD\|381313	cd19087, AKR_AKR12A1_B1_C1, AKR12A, AKR12B, AKR12C families of aldo-keto reductase (AKR). Streptomyces fradiae TylCII, Saccharopolyspora erythraea EryBII, and Streptomyces avermitilis aveBVIII are founding members of aldo-keto reductase family 12 member A1 (AKR12A1), B1 (AKR12B1), and C1(AKR12C1), respectively. TylCII acts as a NDP-hexose 2,3-enoyl reductase. EryBII is a mycarose/desosamine reductase involved in L-mycarose and D-desosamine production. aveBVIII functions as a dTDP-4-keto-6-deoxy-L-hexose-2,3-reductase.	0
NC_013517.1\|WP_012862668.1\|3406237_3407272_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.31876e-110
NC_013517.1\|WP_012862677.1\|3415640_3416144_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|377139	pfam03830, PTSIIB_sorb, PTS system sorbose subfamily IIB component.	4.16966e-49
NC_013517.1\|WP_012862662.1\|3391504_3392140_-\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381617	cd16896, LT_Slt70-like, uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	2.48443e-30
NC_013517.1\|WP_012862675.1\|3414004_3414814_-\|PTS-system-mannose/fructose/sorbose-family-transporter-subunit-IID	gnl\|CDD\|377079	pfam03613, EIID-AGA, PTS system mannose/fructose/sorbose family IID component.	2.69639e-98
NC_013517.1\|WP_012862676.1\|3414813_3415641_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|377077	pfam03609, EII-Sor, PTS system sorbose-specific iic component.	3.74168e-64
NC_013517.1\|WP_012862659.1\|3389658_3390141_+\|flavodoxin	gnl\|CDD\|180850	PRK07116, PRK07116, flavodoxin; Provisional.	1.6569e-36
NC_013517.1\|WP_012862660.1\|3390198_3391179_+\|aldo/keto-reductase	gnl\|CDD\|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	0
NC_013517.1\|WP_012862679.1\|3416617_3417355_-\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	4.65561e-76
NC_013517.1\|WP_012862664.1\|3401461_3401920_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|334031	pfam00359, PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.	5.09874e-30
NC_013517.1\|WP_012862672.1\|3410492_3411935_+\|alpha-amylase	gnl\|CDD\|236518	PRK09441, PRK09441, cytoplasmic alpha-amylase; Reviewed.	0
NC_013517.1\|WP_012862670.1\|3408569_3409595_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|182305	PRK10206, PRK10206, putative oxidoreductase; Provisional.	8.88396e-106
NC_013517.1\|WP_012862673.1\|3412007_3413528_-\|phosphoglucomutase	gnl\|CDD\|215211	PLN02371, PLN02371, phosphoglucosamine mutase family protein.	0

>NC_013517.1|WP_012862668.1|3406237_3407272_-|LacI-family-DNA-binding-transcriptional-regulator
MNPKEKISMKDIAKLAGVSASTVSRIINNSGQISEKTKKKVFSLMKKYNYTPNMVAKSLKINKSKSIGIIITNIQNEFFSEIVLGIEDFFFKVGYSVFICNTSQNPKKEMEYFKILDSKLVDGIICISALEKTPKDFYSNHRKIPMVCIDRIFDPHASDTFYVESSHFDGGFLATEELIKKGCRKIMILTKKRSFSASQKRFEGYKEALKKYDIPFDANLVMKFDGNLSSFDETKKIVDKAVSSGLEFDGIFATSDWRAYGALISLKEHGISVPEKVKIIGFDNISISKYSYPKITTVNQDREAIIQQVSNLLFDLMNDAELPDEIKNKKHIVIPVSLVNRETT
>NC_013517.1|WP_012862667.1|3403529_3406166_+|mannosylglycerate-hydrolase
MQKTKVHIIPHSHWDKEWYFTSSRSKIYLIKHIKEVLDVLENKEDFGFFLMDAQSSLIEDYLKYCPSDEERLKKLISEKRFLTGPWNTQTDQLVISQESVVRNLYYGIDYADKMGHSMPIGYAPDIFGQGGNMPQIYRHFDIDKFLFWRGVADSRLKQTEFIWEGDDGTQMLAVQIPFGYYYGANIPEADEEIIHYLDEKISALENKASTKHVYFPNGLDQAPVRKNLPELVKKFNRLNSEREYIIDSPENFMAEIEKDCQNLPIIHGELTEGKNSRIHKSIFSSRADLKQANNKIENFIVNILEPVLSISYSLGNRYPHEELAEIWKLMFANAAHDSIGACNSDSTNRDIASRYKIAQDMSENLLDLNMRLISRKIDHNSDFSFNIFNPLPYERKCVTEFTAYIPEDDFRIFDLDGKELKYVIKEKTELTDYVLSQHIYLNPSKKAYMPEKVYKAKILVETGSVPAMGYTQFYIDMAKKEKQKVEKEYQINEIENEFYHITFEANNTLTIKDKKSDKIYHNQMIFEENGDDGDSYNYSPPRKDMVIRSSDLQNTKSEGTKVYKSDVENVLKLQLNMKVPKDLESRSKGINSENFRLNIEVSLRKNDDLVRFSVKADNQVLSHRLCVCFDTEIAGKFSTADQLFGIVQRPVYLPEMKTWEKEEWQETPVSIEPMQSFVSLHDENHGTAVITEGVREYEIIGKKYDTIRLTLFRTFSHMGKTDLLYRPGRASGESIIETPDAQLLGEFDFSFALTFFEGSFDNAHIAKKAKEYLTPMPVYQFSEFLNGRLIYVYCDEEKTLPQKYSMFSYKDTEAVMSAFKKAENGDGYIIRYFNPFISKTVSIKNNIADKAVMLDERSSTESKNELNFCEFQTYLLKL
>NC_013517.1|WP_012862666.1|3402403_3403504_+|PTS-fructose-transporter-subunit-IIC
MKKKLYEARDHLMGGISYALPVIIGGSLVVAVAKIIGFAGGVSNLDDYAQAGGFFHYVWMFQNVGWSAIGLLNLVLSGYIAYSIAGKPALAAGFVGGVLASTTNAGFLGAVVTGFFAGWITNKIKNNVKIKGAAASSVPLIILPLLTIGLTGILMALILGGPLGWINTSLLNWVTKMSENNTNVVILAVILGAMIGFDLGGPVNKAAWMAGNALFMSGVYLPSILVNVAIWIPPLGYGLATLIKKKNFSETFKEAGSGAVIMGVIGITEGAIPFTLQSPGKLIPLNVIACAAGTAIAALLGIYVKMPPIGGMYGFFSVGNGWAYLVGGISGALIIGFGANFLVDFTEKDNGAVAETVSEEIELSFD
>NC_013517.1|WP_012862665.1|3401916_3402234_+|PTS-fructose-transporter-subunit-IIB
MKIVGVTSCIAGLAHTPMAAKALEKAGAKLGHDVRMEQQGAMGKVNEITESEIKSADLVLIAADKVVEDEDRFAGKQIVRVKIGQCVSNAEGVLKKIVEAMEKRK
>NC_013517.1|WP_012862664.1|3401461_3401920_+|PTS-sugar-transporter-subunit-IIA
MILENNQIFLDEKLSNKDNVMLFIAEKSKLLGITDNEKEIYNKLWEREKEYPTAVQDLIAVPHVKSDLIKTAKLLFIRLTEAVDWDSPDGFKVKSVFVILVPEKDAGQKHLEILSKVAVSLLEEDFQSMILNMKTGDELIKYIKENLDGDLL
>NC_013517.1|WP_012862663.1|3392510_3400793_-|autotransporter-domain-containing-protein
MKKNKKLLIPFLALNAILPAYAKGAAVSESVKYDSLYNKMVKNLEQGKPNQKNYQIIEQILKKRNKELKDLYVQGDYIVKPEYLEWQIFASGFYGEKDRGDNNEYNLSYDSEGNLVSSSDQNSSDKKIKDLRTKKYIQIGATIPVKTVADFTINPNVDLTIKDIAPITIVPPVTKIEKAQSISLPNITAPTMTAPGMNLSVSPTVNITPPSVNFSFAAGHNAGAPPGPLAGTTNESVAPKANGILTTADFSKTVLESTNSVWRFYSVSTGAGQSKIIASDVVLTARNEKDGNGYFTFENSPGATMISILGTVTILPNSQTNYVVGDTVDGDARATTYNGGTMNIFAAQTHKTLNAATDTPSGGGAMMYIPTNHTEPNQIIPGVNSNKYLVNGENGTIHIKGFGNYGVMNVDMDHTVRGYGSGAGHINDRFSDPANPGKFIPNANGEVDINIILNQGTVLVEKTQGAGGFDSQYGNVALSAFAQEKPLPTSAVFNNYLGMIFDNTTFMYNDGSIKSVSGNNMLMQHKGSGQMINNGVLDIESGQTIGMIRENIGHRGYTVTTSNTVTSHTIWDAANSRARAVNDGIINIAASAKDVLGMKGMGYDGNGINDNVNSRVLIYNAESKVTVENGDGVLNGIDIDEDGGVSGSHKIDIDRSNVNSYGANMGGLVPNLKETLDESKTVTFTLNSKTYTTKDGVIFVGGKNAAGLYAETKNALRTSGFSGNGINNPNSSALPDASHIDYAKAINNIDGKIFVYASGNASGNYSIGIAGQYASLDNKGDIFLGLLPQAGAITGKGSTVNTEGGVSSAQEQYIGIYGNGSSVYNTGYISDKASSGSKANYSINGIGIFAEKKAIANGSAGYIANNGEIILGTGGKGVAGVGISASDMITLISGGNIEVRSTAANMGVGVYGSYADSDKTDSVISKTGISGNLNILGERAIGVYFKNGKANVHDMNITGTDTVTPDEVDKAFGVAVESSDLKIGNKVKIELKGEDNIGIYGKILTYTDAITSASRSDYIDIALGSGGIGIYLEDITNNSLVKVNNIVTGNSTATRNSGGIALKSTTNRAEINAGNITIGSAEAAGEGFGIFVEGASAQDSKITAGNITVNQKSGIGVFGKNVKEITAGNIKAGKTGVYQESSSTTAGKLSAGSISLIGNEDSMIGVYTNGSSAAVDTEIAGLDMQNAKNDSTGIYIGSGSFKNTGSINIKALDSSFGIYIKGVTGHNTVDFGTGSRTVNLGNDSIGLYLKNSQVSNMITDITIGDTTGAPGTQAGVGMFLEDTAVTGAVNTNIISGNKTVAAYFGANTGNITYNGNVQVGENSLGIYKNGGTLTRDPSKTTIFSGSANTESIGYYLENSVLDYSSNALTAGTLTMNNGIAFLLKGAGSQVTVNGVPITNSDLDKLGLDPKVERFVYSDKQEIITEDVTLDPSVRHYGYHAVNGRIELNGNIYTNNNILGTYGILAQGRYGSGTEEIFISGGKTIDMTNSTGSIGVEVLEGARVKNNGTIKAGKSSSTSSGIGILAESTALLTAEAENTGTGVIEVLDSGIGIYLDSAELGGNILNNGIIRSTENNTLGIYSKLSSSGVVNSVPAATLTNNGDILLKNDSFGIFAENSNINNSGNITVGDTVSGSSVAVYGSKKSIINNTGGTITAGENGLGFYLDNSTLNITGGSFNTGKGILVYAANESSVNYAAGNTVLGDKIGFYLDNSTADFNSKEFTVLDNGVGMYVTNTQAGPVQQSAVKSLGKLILGSNATGIYLKNADLEPVTIGMTNYTLGGAIEINGTNSAAIMGVNSNIENTSNISSSASLNKGIVLKADDSNTYSLKNSSNISLLSDKSIGIYGTTQTGNINIDNTGTINLGNTGSIADASVGIYGTAGVNITNNGTITGGTNTVGLYSNGGTLINNTGITLSHGSVGVYASGGTADINLGSSVTVGDNGAVALYANNGAVLINYSSNISAGTDSVIGYAKDSGTKLDNRAALSIQEEGVGFYTNNGHIINSGTLSSAGNGIIYLYGNNGTIENNGQISGSAHGYGVGIYGSNSDIKNTAAIVLGDSHIPHPNDLSNKDNRFSVGIYGEGSKIDNSSNITVGENGIGIYSYAQSGDITNSGQITSTRDKAIGIFSEVGKNGKIINSGLIDLAGNSVIGVAINKGGTLDNLGTIKVSGTESIAVLAESGSVVNNYNTIDVSGTNSVAVVLKDKSAFINHPGATLILGSGSLGILTDSTSTSNIASGSLSDTSITLPSLASVPIYEPPQIINSGIIKVEGNFEVPYDGVVKVKVDPDSVRELTHAEKVSSGYDLLELENVIMISNAVKYEADSFNVKDVTVTPDFTEGTNALTYKLENVFMPRVSNAGVTSGIASVYSESYTWDAIPVTNADGNVDIWMKKIAYKDLMEGEWYEDFGAAMDEKYAGSTGDAGKIFDKIDRITNGTDFERIMESLGGNIYANINEREDDIARAFENSLSLLQNSHNNTKENVKINVIAGKGKTTEDTPGVTGYNYEMVGVLALREVERTYKHTFGYSLGYVHTDFEFKDGMSSEELVDTLQIGGHSKYKSNDWILRNDLTGRASFHNIDRNINWPSPYGRSEINGSYETYSITSNNTFGRELSIGKNSSVTPYGGLRVMYVTRPDFEEKGLERLEVEGNDAWSVKPKLGVELKTAIPLGSSNAWKIKGALDLGYEYELANLNEREKARLVAIEDGYHKLAEPDDEKGAFRGGVSIGVEVEDRYGIFLTGEYKAGNDKQNDYRAGVTLKAVF
>NC_013517.1|WP_012862662.1|3391504_3392140_-|transglycosylase-SLT-domain-containing-protein
MKKMILILFFISFFSFSGESEMVAYMKKNNSRLSEKEAKDIYKNVVRYSTEYDFDPILVFSVMKTESNFRHSTVSTAGAKGLMQLMPENFEEFKVDNSIRGNIRGGIKHLKRDYDNTQDVTKTLVCYNAGCGRLQNNEWRKIRETRNYVKKINAVYPEIKNIYYVNVENPFASSILANGLAVIGSYKILDSIKNENHTENKEYLYWRESYI
>NC_013517.1|WP_012862660.1|3390198_3391179_+|aldo/keto-reductase
MEYIKLGNTGMDVSRFCLGCMGFGDSEAWVHKWLLNEEDSRPVIKKALDLGINFFDTANVYSLGKSEEILGRALKDYANRDEVVIATKVHGKMHDGPNGSGLSRKAIMSEIDKSLKRLGTDYVDLYIIHRWDYNTPIEETMEALHDIVKAGKARYIGASAMYAWQFQKALHTAEKNGWTRFVSMQNHLNLIYREEEREMIPLCKEEKIALTPYSPLASGRLTRNLSETTKRSETDQIAVSKYGSTEEADRLVIERLAAVAERRGIPRLHVALAWLLQKEPVTIPIIGATKLSHLEDAVPALSVKLEPEEIAFLEEPYVPHKVIGAV
>NC_013517.1|WP_012862659.1|3389658_3390141_+|flavodoxin
MSKKILTAYYSHSGNTGEIASYIQKQTNGALFEIIPAVPYPTGYNDVVRQAKIEIQSGKKPELKTKINDTESYDIIFVGSPNWWGTIAPPVAAFLSEHDFSAKTIVPFCTHGGGGYGSIFKDISLLCPNSNILEGFEVFGKGNGNISEKINLWLNEIGIK
>NC_013517.1|WP_012862658.1|3388658_3389642_+|aldo/keto-reductase
MEYRTVGKTGIFVSNLCFGTMSFGGNADAETSKSMFKYCRDTGINFFDTADVYSGGRAEEILGECIAECRNEIVLTSKVFYPTGEGVNDKGLSRRHIINAAENSLRRLKTDRIEFYFVHAFDDNTPMEETLLALDLLQKQGKILYPAVSNWAAWQIAKALGISAKEQLARFELIQPMYSLVKRQAEVEILPLAASEKIGVISYSPLGAGLLTGKYGINKRPDQGRLLEEARYKDRYKDDNNFIIADKFSAYAEKHDVTPSSLAVAWVMSNPSVTAPIIGARNIAQLQDSLGALDIKMTPEWREEISSLSNTPAPATDRAETLLPNWK
>NC_013517.1|WP_012862670.1|3408569_3409595_-|Gfo/Idh/MocA-family-oxidoreductase
MLTIAYIGNGKSTNRYHLPFVLQRKDKIKVKKIFARHPEKLEWDRIPGVLYTDNINELLHDEEIDLIVICTRDDNDLHYNYAKMVLESNKHCLVEKPFMSSAAQAREIFSLAGERNLIVQAYQNRRFDSDFLTVKKVIESGKLGELLELEMHFDYYRPEIPESVREFQPEMSYLYGHGCHTLDQVISYFGKPENIHYDVRQLLGEGRMNDYFDLDLYYGNFKVSVKSSYFRVKERPSFVIYGKKGYFEKVTKDRQEEHLKVFYMPDNKDFGIDLPEHYGTLIYYDNDGQYHEEKVVSERGDYGRVYDDLYEAVIHGKEKTITDEQTLLQMEILEEGIRNLK
>NC_013517.1|WP_012862671.1|3410171_3410462_+|hypothetical-protein
MDKNIKDYLDLKKEIVAIITSGYESRERLILLSEIKNENNEKKVQSLIEISTQINQNSRNILNELSEVEDIDQIKDLKEKLLNLTECYRQLIEEIF
>NC_013517.1|WP_012862672.1|3410492_3411935_+|alpha-amylase
MENGVMFQYFEWNLPADKKHWKRLADDAEHLREIGINAVWIPPAIKGTSDLDVGYGAYDLYDLGEFDQKGTIPTKYGTKEELKAAIEELHKYEISVYLDAVMNHKAGADETEKFLAQEVDPNDRNKPVSDPYEIEGWTKFNFEGRNNKYSDFKWHWYHFNGTDFNNLNQKNAIYRIMGEGKSWDENVDDENGNYDYLMFANIDYDHPEVVDEMNKWGIWVADELNLDGFRLDAIKHINSNFIEGFLKEVRKVKGDKFYAVGEYWKDDLDSIQEYLNNVDYEVELFDVPLHYNFFTASKEGEAYDLRNIFENSIVTNNKLFSVTFVDNHDSQWGSALESQVESWFKPLAYAIILLIADGYPCIFYGDYYSLGDKESPHRWMIDKLLYTRKHYAYGEQINYFDDPNLIGIVRKGAEEHPDSGLVMILSNHTEGSKKINIGKEHAGETWFEITENIKDEIQIDENGEAEFRVNAGNVAVWVKK
>NC_013517.1|WP_012862673.1|3412007_3413528_-|phosphoglucomutase
MQKKLERLQSSSDIRGIAVQFEDREVTLNRETAALLAQGYISHISKRLGKNPEDMRVSLGVDSRVTGEKLKCAFAEVLMDAGMEVYDFGLATTPSMFMSTVFENYKCDSAVMFTASHLPFYYNGIKFFTDKGGFENEDIKEITEKAIELSEKQAKKHIQKGKINRTSILKDYSEFLVNKIREGVNSSKNYEKPLEGMRIIVDAGNGSGGFFAKEVLEVLGADTTGSAFLNPDGNFPNHIPNPEDQTAINFLKKSVTENNADLGIIFDTDVDRAACVDKAGNEINRNRLIALTSAIVLDEFPGSTIVTDSVTSDEVHEFIVRSGGKHFRYQRGYKNVINKALELNRQGIQCHLAIETSGHAAFKENKFLDDGAYLTAKILIKLAKLNEEGKNIEDLLEGYKEPEESKEIRLRITADSRNEYMDKLMKDIETHSKKTENWKQVKENYEGIRVNCTYKEGKGWFLLRSSLHEPIICINIESNFQNGTDLITKEVTDILKNYKEIEMSGL
>NC_013517.1|WP_147289491.1|3413693_3413999_-|hypothetical-protein
MDRKEILRLNNTLISEFVRKKAVDRQNSICCDEIKIGCDEKIKRFLIQELIKQGFVYNGEDNKVWFEHKKWESEFKKTYIIYYGILLLPVISGLLLIILRK
>NC_013517.1|WP_012862675.1|3414004_3414814_-|PTS-system-mannose/fructose/sorbose-family-transporter-subunit-IID
MKKLSRKTLNTCWIKWFFGHLHSMSFQWLQAFGFATSMAPVLRELYPDNKKEQISGLKRHAAFYNTEPQLGCVVMGVVCGLEEEKANGADIDDEMINSIKLGLMGPLAGIGDAMIPGMYIPLLLSIGIGMSGNGSVLGPLFYVFTYILSMLLATHFIFMKGYLLGTKSIDLIIGETTRKIRNAFNLLGAIVVGGVGASYVHVATRAVIKTSETSSIVINDMINGIFPNLLSLATILFCWWLMSKKKISSVKIMLILFIISLAGVAAGFF
>NC_013517.1|WP_012862676.1|3414813_3415641_-|PTS-sugar-transporter-subunit-IIC
MYINLIQALLISIFAYLGTLPSLLGSTVGWYVLGRPFVSGAIIGLILGDVQAGIIIGAAVQIVFIAMITPGGAMPTDLNVAAYIGVGLGLISYKSGASVESAVAIATAVGAVGVVFHNFQMIVNTLWNQRSVKYIETADYKQLLLNHSVYPQITLFLFRALPTFVILYYGQRYASEILRVFPADSYIMRTLTTLGGMLPAIGVAILINAITKKNIDILPVLLGFTLVVTLGINMLSLAIIAAFFAYSQFHNDKGQTLQTEEVGVKAELDDMEEEL
>NC_013517.1|WP_012862677.1|3415640_3416144_-|PTS-sugar-transporter-subunit-IIB
MAISFIRVDDRIIHGQVVTRWSMERPCDGIIAVNDKCATNDLLKNALKAASTKKTFIWTHEQFLQKMDEAVKSGKNYFVITKEPVTMAKLLVDNGMTVNVQTLNVGPQSARGNTIYVNKNCDVTNEEFEAYEKIHQAGYNVEFQLVPDSTKVTYESIRSKVQKKGDN
>NC_013517.1|WP_012862678.1|3416161_3416605_-|PTS-system-fructose-subfamily-transporter-subunit-IIA
MKYMLLVSHGTMAKGLYDAAGMVLNCGEKLSYLCLSEDMDVEKYNRELETKLAEIIEKDKIYDYEDFVICSDIMGGSPCNSALALLEKQNLINKTFVITGMNLPLVTSILLEDEKLDTEKINVLIDEARESIQMLNFNSCSETDEEL
>NC_013517.1|WP_012862679.1|3416617_3417355_-|deoxyribose-phosphate-aldolase
MKPIKKASEMNLEELGAYIDQSVLKPEFTQEEIRKYIQEGIDYKCKTVCINPASIDIANEMTKGTATKVCAVCDFPFGTSATESKAIQAEECCKKGIFELDIVANYGWIKSGMWKEVEEDIRAVNEVCKKYNIALKVIFETDALTIDEVKKATEAAIAAGADFVKTSTGFFTGGKNEGATVEVIKAMMDTAKGRCKVKGSGGIRTREYFLELIDMGIDRMGVGYKSTPVVLGLDKAGKTADKEIY

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Crispr_ID: NC_013517_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_9

3555289-3555387

Orphan

Consensus_repeat	Method
TCCGTCACCTGTTATATTTATAGTACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013517_9

>merge|NC_013517|9|3555289-3555387|CRISPRCasFinder
TCCGTCACCTGTTATATTTATAGTACCTGTGTTAGTGATTATTGTCCCAAGGTTTCCGTACATTCCTATAGCTCCGTTACCTGTTATATTTATAGTACC

>NC_013517|9|8|3555289-3555387|CRISPRCasFinder
TCCGTCACCTGTTATATTTATAGTACC	TGTGTTAGTGATTATTGTCCCAAGGTTTCCGTACATTCCTATAGC
TCCGTTACCTGTTATATTTATAGTACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_012862785.1\|3546595_3547549_-\|transketolase-family-protein	unknown	unknown	gnl\|CDD\|226467
NC_013517.1\|WP_012862782.1\|3542934_3543732_-\|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455
NC_013517.1\|WP_012862789.1\|3550294_3550726_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NC_013517.1\|WP_012862784.1\|3544454_3545870_+\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NC_013517.1\|WP_041310967.1\|3548402_3549773_-\|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|171824
NC_013517.1\|WP_012862798.1\|3563403_3564384_-\|phosphate-binding-protein	unknown	unknown	gnl\|CDD\|270284
NC_013517.1\|WP_012862788.1\|3549790_3550060_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99905
NC_013517.1\|WP_012862800.1\|3565910_3566333_-\|DUF2059-domain-containing-protein	unknown	unknown	gnl\|CDD\|378261
NC_013517.1\|WP_012862783.1\|3544051_3544300_+\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_115388859.1\|3562348_3563311_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270284
NC_013517.1\|WP_012862799.1\|3564631_3565879_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|224365
NC_013517.1\|WP_012862786.1\|3547548_3548382_-\|transketolase	unknown	unknown	gnl\|CDD\|226468
NC_013517.1\|WP_012862790.1\|3550737_3552801_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226234
NC_013517.1\|WP_012862791.1\|3553182_3553596_+\|DUF1311-domain-containing-protein	unknown	unknown	gnl\|CDD\|377758
NC_013517.1\|WP_012862796.1\|3561953_3562328_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012862793.1\|3560475_3560745_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012862802.1\|3567244_3568540_-\|M18-family-aminopeptidase	unknown	unknown	gnl\|CDD\|235073
NC_013517.1\|WP_012862801.1\|3566409_3567225_-\|5'-nucleotidase,-lipoprotein-e(P4)-family	unknown	unknown	gnl\|CDD\|273674
NC_013517.1\|WP_012862795.1\|3561045_3561243_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012862794.1\|3560761_3561034_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012862785.1\|3546595_3547549_-\|transketolase-family-protein	gnl\|CDD\|226467	COG3958, COG3958, Transketolase, C-terminal subunit [Carbohydrate transport and metabolism].	5.58239e-141
NC_013517.1\|WP_012862782.1\|3542934_3543732_-\|Mrp/NBP35-family-ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	4.89866e-118
NC_013517.1\|WP_012862789.1\|3550294_3550726_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	1.65716e-30
NC_013517.1\|WP_012862784.1\|3544454_3545870_+\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NC_013517.1\|WP_041310967.1\|3548402_3549773_-\|PTS-ascorbate-transporter-subunit-IIC	gnl\|CDD\|171824	PRK12996, ulaA, PTS ascorbate transporter subunit IIC.	0
NC_013517.1\|WP_012862798.1\|3563403_3564384_-\|phosphate-binding-protein	gnl\|CDD\|270284	cd13566, PBP2_phosphate, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.27699e-41
NC_013517.1\|WP_012862788.1\|3549790_3550060_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	1.34767e-33
NC_013517.1\|WP_012862802.1\|3567244_3568540_-\|M18-family-aminopeptidase	gnl\|CDD\|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NC_013517.1\|WP_115388859.1\|3562348_3563311_-\|hypothetical-protein	gnl\|CDD\|270284	cd13566, PBP2_phosphate, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.82358e-42
NC_013517.1\|WP_012862786.1\|3547548_3548382_-\|transketolase	gnl\|CDD\|226468	COG3959, COG3959, Transketolase, N-terminal subunit [Carbohydrate transport and metabolism].	5.37135e-121
NC_013517.1\|WP_012862790.1\|3550737_3552801_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.628e-26
NC_013517.1\|WP_012862791.1\|3553182_3553596_+\|DUF1311-domain-containing-protein	gnl\|CDD\|377758	pfam07007, LprI, Lysozyme inhibitor LprI. This family consists of several bacterial proteins of around 120 residues in length. Members of this family contain four highly conserved cysteine residues. Family members include lipoprotein LprI from Mycobacterium, which binds to and inhibits macrophage lysozyme, which may aid bacterial survival.	6.64244e-12
NC_013517.1\|WP_012862799.1\|3564631_3565879_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|224365	COG1448, TyrB, Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism].	2.29138e-68
NC_013517.1\|WP_012862801.1\|3566409_3567225_-\|5'-nucleotidase,-lipoprotein-e(P4)-family	gnl\|CDD\|273674	TIGR01533, Lipoprotein_E, 5'-nucleotidase, lipoprotein e(P4) family. This model represents a set of bacterial lipoproteins belonging to a larger acid phosphatase family (pfam03767), which in turn belongs to the haloacid dehalogenase (HAD) superfamily of aspartate-dependent hydrolases. Members are found on the outer membrane of Gram-negative bacteria and the cytoplasmic membrane of Gram-positive bacteria. Most members have classic lipoprotein signal sequences. A critical role of this 5'-nucleotidase in Haemophilus influenzae is the degradation of external riboside in order to allow transport into the cell. An earlier suggested role in hemin transport is no longer current. This enzyme may also have other physiologically significant roles. [Transport and binding proteins, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	3.60493e-71
NC_013517.1\|WP_012862800.1\|3565910_3566333_-\|DUF2059-domain-containing-protein	gnl\|CDD\|378261	pfam09832, DUF2059, Uncharacterized protein conserved in bacteria (DUF2059). This domain, found in various prokaryotic proteins, has no known function.	3.42067e-09

>NC_013517.1|WP_012862791.1|3553182_3553596_+|DUF1311-domain-containing-protein
MKKFILFLVFTLAVSSFANYESDLLGRMKPVEQKSGSMLDSAQTTAEMINAVSYASNEWDAELNKIYKLLMSSLSKDGQNSLRNAQRSWIKERDKKIAGENSGGTIDLVNKNSIFLEETKKRTIELARIYDKLKSKT
>NC_013517.1|WP_012862790.1|3550737_3552801_-|PTS-sugar-transporter-subunit-IIA
MLNHREQELLDFFVKNGKFTYEEICNKYSISERAARYNIDNINYFLEVLHISPVKKSGKDLYFDNTQDISNIYTILNDIEVFSQEERLEILKFILCFDKTGLNLTKSSEKLRVSRTTIKKDMKILKKEMIQEGFDVAYKNNEGYRLEGEPYKLELYKIGLLKEILILVNTKDKESSYKKTMSELCDSLFNIKGKESIKEFILNIHKNLSLNISDEIFYVIYAYLIILIDNHKNIQSLYTRSSNKSFLLGTKEFLVIEKEIKKIKELKNAEIPKERILELADFILGITTNEYSSNNLENWIHEEVFIKKMVNEFNKYIELDITSDEILIDCLIYHMKPVIYRIRNNIRVTNPVFKELIISKDPILEIVRIITRDIEKMFGIEFPEEELALLAFHFKASIDRNTHQNLKRILLVCGLGYGSSRLLEQSIKENYNVDIVDVLPYYLLKDALKNYKNIDLILTTLDITEKYKIPVVKINPLLKQEDYLEMAKYNIPKNDNKIFLSKILKIIKKNTKIVNEEILINEIKQEFKNRIIDDVDYKTTHIKEFINEKSVVVLDEVESWEEAIKISGSLLVDNMYVKTEYIDEMINLVKKYGSYIVIDDGIALPHAGISRNVLKLGVGVLVVKKPVLFSDKKSANIFISFASNENKSHLTILNDLFDLITKYDLKGELLQAKDKHEVIDYFIKTKV
>NC_013517.1|WP_012862789.1|3550294_3550726_-|PTS-sugar-transporter-subunit-IIA
MLKEFLNGNINLIKGTSDWEESVKTAANPLLEKGFISENYVNAMINDIKRLGFYIVLREGVAMPHSRPENGVSKTAMSLLKLKEPVKYGENEVKLIFILAAEDSEKHIEALTGFSELLQNDEEVEALMKAETTEEVIGIINKY
>NC_013517.1|WP_012862788.1|3549790_3550060_-|PTS-sugar-transporter-subunit-IIB
MKIMAVCGSGLGSSFLVEMNIKKVIQKIGVDAEVEHSDLSSATPDAADLFVMGKDIAASASVPENKLVVLDNIIDMNELEEKLSKYFGK
>NC_013517.1|WP_041310967.1|3548402_3549773_-|PTS-ascorbate-transporter-subunit-IIC
MNGLLMFVFDILKVPSVLVGLMALIGLVAQKKPVTDVVKGTIKTILGFLVLSGGAGVLTGSLDPLGQMFEQAFHIQGIIPNNEAIVSIALGEYGAMTAYIMAFGMIFNIFIARFTRLKYIFLTGHHTLYMACMIAIILRVADFDGVQLVLVGSIILGLIMALFPAMAQRHMRRITGNDDIAFGHFGTLGYVLSGFVGEAVGKGSKSTEDMNLPKNLSFLRDSSISISLTMMVIYLMLAVLSGREFVETNLSNGDNYLVYAIIQAITFAAGVFIILSGVRLILGEIIPAFKGFSEKMVPSAKPALDCPVVFPYAPNAVLVGFLFSFLGGIVGLLVLGQLNMVLILPGVIPHFFCGATAGVFGNATGGRRGSMLGAFANGLLITFLPVMLLPVLGSLGFANTTFSDADFGLVGIILGNMARYMDKNVITIIAVAILAILVALNYMMPKKKMPEADAAK
>NC_013517.1|WP_012862786.1|3547548_3548382_-|transketolase
MENYNEIKKLAKDIRISMLKMLLNLGFGHFGGSLSVVETLAVLYGAVMKIDPKNPNWEGRDYMVLSKGHAGPALYAALAIKGYFPKEELMTLNVNGTHLPSHPDRLLTKGVDATTGSLGQGVSLATGIAMAEKLSGKDNRVFTILGDGELNEGQCWEAFQFIAHHNLNNLTVFVDYNKLQLDGTLEEIIKPFSLTEKFKTFGFDSVEVKGDDIEGIYNLLKNPRGENERPLAVILDTKKGQGVKYIENLKNSHHLRLTDDVKAEIEKAVAELEGEVE
>NC_013517.1|WP_012862785.1|3546595_3547549_-|transketolase-family-protein
MYKICSERKKDDMEMRKIYSTTLLELMKKDERIVALEADLMGSMSTDIIQKELPGRIINGGIMEAHIAGMAGGMSIAGKVPFFHTFTAFASRRCFDQLFMSISYQKNNVKIIASDAGITAVHNGGTHMSFEDMGIVRGLAGAVVLEVTDGVMFKNIIEQVAQTEGFHWIRTMRKNAEKIYEDGSVFEIGKGNVVKDGSDITLIANGIMVSEALKAADMLKEKGYNAAVIDMFTLKPIDKDLIIKYAEKTGKIVTCENHSIHNGLGSAVAEVLAENYPAKMRRVGVKERYGQVGTLDYLMKEYELTAEDICKNALELL
>NC_013517.1|WP_012862784.1|3544454_3545870_+|leucyl-aminopeptidase
MNISVINNFKDNFDTLILPVSKNRKINSHNKELDKKINKYIELYSFSYSDDKFLSFDLEADNKLKQIVLVNIDLPDKLQIRDTLFNVFGKISEKSKNILFINSDLFFDEYIITEIFILRYYKFIKYIENSKKHKHHLFILTNKDIDLTETIELANSVNTARDLVNEPSNVLYPETLAESALSLGEKYGFEVEVLNKKDIKKLKMECFLKVGEGSDKEPKLIILRYHGNKKDKNKIGLIGKGVTFDSGGLSLKPSDSMIEMKSDMAGAAAVISAVCTASKMKIKKNIIGVIPACENMINGSSYKLGDIIKSMNGKTVEIHNTDAEGRLTIIDAVTYAIRHEKVTHILDIATLTGACMVALGTDITGVVTNDGNMLKVLKKASEISGELIWELPNHSTYKESLKSPNADLKNVGTRWGGAIIAGQFIEEFVEKLPWLHLDIAGPAFIESKSKFGSAGGTGAGTRLLYEFIKNF
>NC_013517.1|WP_012862783.1|3544051_3544300_+|hypothetical-protein
MSEYLSDKPKKLIIKDKNGNIKNYQEFEHNNNGDPIYYKKVENERTTVELTYEYEYDEIGRKKVTKIADLITDNITIMEYEY
>NC_013517.1|WP_012862782.1|3542934_3543732_-|Mrp/NBP35-family-ATP-binding-protein
MHSNINMENQKSKIKENMSNITNKVVIMSGKGGVGKSTLSVNLAYGLSMRGYKVGILDADLHGPNIPIMLGVEGEKLTDLSVPYKINENLCTTSLSFFLPSTDPIIWRGPQKMGAIMEILENVVWGKLDYLIIDLPPGTGDETLTIAQNVGVGTKAIVVTTPQDVALLDSRRSVKFSGLVNMELIGIIENMSGFICPECGEEVNILKKGGAERMANELKVNFLGSIPMDKNIAEAGDSGEPYIQNESEASIRLNKIIDQILDKVK
>NC_013517.1|WP_012862793.1|3560475_3560745_-|hypothetical-protein
MKKMILIISLGALWGMVLNAAPTYEYRRELREGARGKWINLRQHLNSGQRLEREITKVDKQIDRKVKEIQEIEDLLFRIEQYKVENNIR
>NC_013517.1|WP_012862794.1|3560761_3561034_-|hypothetical-protein
MKKIMILVAVISFFSFSDDIKIDRAVKESITKDFDQDGKYSAYEKALRKAQESIYVTLPEHRGYWYSTLDKIKAEEEELLPDETARMRRR
>NC_013517.1|WP_012862795.1|3561045_3561243_-|hypothetical-protein
MRIVFFTFLIVFGAVSAAESKNVKTDVALEMERADKIESYKAKKDLAWHKTEYNKVLKYLKKTKK
>NC_013517.1|WP_012862796.1|3561953_3562328_-|hypothetical-protein
MKILSYKPREEKYGFILFSAKFGDRWDSIKEEDHIFIYSSDFEHITESVKSIYPFADPETKEIQEFFDACGMNCIPAVEWSKILIDLYKKEYKDIYLQRFIENFCNWIMDKKSDSDEIMIWGTL
>NC_013517.1|WP_115388859.1|3562348_3563311_-|hypothetical-protein
MMILSVIGIGVYKYVYNSGKLKRDTSVDQVADGFSIQRYVPFSGENSLYIFEKEPEISIESNYPKLDGATAAYPVYGSIVQAVYKGLNEETVKDYVQCNTTPVAYERLINKEVDAIFGAEPSKSQLEMAKKAGVELELIPLGREAFVFLVNKDNPVSNLSVEQIQDIYTKKIKNWKKAGGQRAKIMAFQRPENSGSQTIMENKVMNGIQMAPPLEEEYYELMGGIVNGVASYRNYKNSIGYSFRYYVTGMNKNDNIKLLSINGAEPSRENIRTGKYPYTIDFYIITRKDVKNKNLDMLIEWILSDEGQEVVEKTGYVPIK
>NC_013517.1|WP_012862798.1|3563403_3564384_-|phosphate-binding-protein
MKRIKVFFLLLITTGAVTFSASKSIMLKPDYDVERVVGEVDLWDYTPFAPGNLLYKFEKAPSISISEDYPTLDGATAGYPIYGSIVQAVYKGLDDDTIWEYVQCNTTPYAYERLINKEVDAIFVLEPSKKQLEAAKKAGVELELIPIGKEAFIFFVNKENKVSNLSVKQIQEIYTKKITNWNKAGGKSLKIQAFQRPQNSGSQTIMENRVMKGIKMTPPLKEEFFMGMGGIIRGVADYRNYEGSIGYSFRYYTTGMNKNDNIKILSIDNVEPSIENIKSGKYPYTVNFYLVTRKDVKNKNLDMLIEWILSDEGQEVVEKTGYVPVK
>NC_013517.1|WP_012862799.1|3564631_3565879_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MLANHSKDKSIVDKVFTVVAKAKEAKEKFGQENVIDATIGVLCNEDAQFVNFKTVSEVYKNLPDNEIAAYASSFSGDPKYLECVKEVVLGKNYGEEFKDSFIDAVATPGGSGAVSNTIWNYVDKGEKILIPDWMWESYKIMSEEFGVKYELYSLFDENGAFNTADFEQKAEKIIEEQGKVLAIINDPCHNPTGYSLSMDEWKELRDFFIKTALKGDIILLNDIAYIDYDFRGEKGAREYMEYFKGLPENVLVIFAFSISKAFTEYGLRVGAQLALSSSKKVTDDFKRANEFSCRSRWSNISRGGMRLFSDIVSNPELFDKLKKERNEYVGLMKERADIFIKEAKEEGIPMCTYRGGFFITVPLGDDTEKIGLELQKENIFTVILEKGLRIAICSVPKRQLHGLPAKIKMVIDRVK
>NC_013517.1|WP_012862800.1|3565910_3566333_-|DUF2059-domain-containing-protein
MKKLFIITMLVFTINITVFSAETPKQKKIKELFQVMDIQAATNEMSEMILNDTDSMKLSKNQKAAMQKEMQSMMDYVLNKQAELYDRHFTEQEIDDILNFYKTPAGKKIIEETPKITKELFTDLMENYYPDMIKRMEKIK
>NC_013517.1|WP_012862801.1|3566409_3567225_-|5'-nucleotidase,-lipoprotein-e(P4)-family
MKSFRKLLCIYIIVIFTGIIHAGSADTDTVQMTYESLQSQQTVLGTVWMQTSAEYRASVYQVFNFAKSRFIEEKSKNYEKKLAVIVDIDETVLDNIYTQAEYIKEGKNFSPKAWDEWRKAEKAAAMPGAVDFVNFIYENGGEVFYITNRKEAERKNTLDNLLKEKFKADNKHLIMKTGESSKESRRNQIEKDYHVAAYLGDDINDFIDAGATAEERRRKVDELSKEFGKKYFIIPNPVYGSFEAAINSDYYKTDYRGRTQMRESSLKGWKE
>NC_013517.1|WP_012862802.1|3567244_3568540_-|M18-family-aminopeptidase
MKKVFAEEFIDFIDKSPSTYHAVKNCSDMLEKNGFIRLDPSKEWKLEKNGKYYIKKTSSTIMAFTVGEEISTECGFRIAGSHTDSPCFRIKPNPEMTVENIIRLNTEVYGGPILSTWFDRPLSIAGRVILKTDNIFRPETVYINIDRPLMTIPNLAIHQNRSVNQGVEIDRQNDVLPVIGLINEAFEKEDFLINLVSKESNIDKKDILDFDLYVYAYEKGTLLGAENEFVSAPKIDNLASVYTGLRAVIESRHVNKGINIFVGFDNEEVGSSTKQGADSNYLMNYMERIYIALGMNRGDFLTAVNNSFLISADGAHAAHPGFTGKMDPTNKPSLNQGVVFKISANQKYTSDGFSISVIKQIIEGKDIKTQDFVNNSKEAGGSTIGPISSTHLETDSVDLGIPMLAMHSVRELCGRDDLYSLKELIKVFFEV

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Crispr_ID: NC_013517_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013517_10

4159472-4159573

Orphan

Consensus_repeat	Method
TGTTATATGGTCGCTCCTGCGTACATCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013517_10

>merge|NC_013517|10|4159472-4159573|CRISPRCasFinder
TGTTATATGGTCGCTCCTGCGTACATCATATATTTATTCTTTTGTATTTTAATTTTTTATTTTAAAACCTTCCTGTTACATGGTCGCTCCTGCGTACATCAT

>NC_013517|10|9|4159472-4159573|CRISPRCasFinder
TGTTATATGGTCGCTCCTGCGTACATCAT	ATATTTATTCTTTTGTATTTTAATTTTTTATTTTAAAACCTTCC
TGTTACATGGTCGCTCCTGCGTACATCAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_013517.1\|WP_041310142.1\|4158006_4158462_-\|terminase	unknown	unknown	gnl\|CDD\|224697
NC_013517.1\|WP_012863306.1\|4150153_4151092_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863320.1\|4162937_4163858_-\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|369151
NC_013517.1\|WP_012863325.1\|4165527_4166265_-\|Bro-N-domain-containing-protein	unknown	unknown	gnl\|CDD\|376797
NC_013517.1\|WP_012863321.1\|4164149_4164710_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863310.1\|4152849_4153227_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863317.1\|4160003_4160810_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863324.1\|4164988_4165510_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863314.1\|4158464_4159394_-\|terminase-small-subunit	unknown	unknown	gnl\|CDD\|377071
NC_013517.1\|WP_012863326.1\|4166257_4166482_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863312.1\|4154117_4154687_-\|phage-virion-morphogenesis-protein	unknown	unknown	gnl\|CDD\|227338
NC_013517.1\|WP_169305423.1\|4161096_4162941_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|238542
NC_013517.1\|WP_012863307.1\|4151095_4151491_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863313.1\|4154676_4156863_-\|minor-capsid-protein	unknown	unknown	gnl\|CDD\|309383
NC_013517.1\|WP_012863309.1\|4151838_4152837_-\|major-capsid-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863316.1\|4159797_4159986_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863318.1\|4160822_4161092_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863308.1\|4151491_4151827_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_115388815.1\|4153228_4154104_-\|hypothetical-protein	unknown	unknown	unknown
NC_013517.1\|WP_012863327.1\|4166450_4166858_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_013517.1\|WP_012863314.1\|4158464_4159394_-\|terminase-small-subunit	gnl\|CDD\|377071	pfam03592, Terminase_2, Terminase small subunit. Packaging of double-stranded viral DNA concatemers requires interaction of the prohead with virus DNA. This process is mediated by a phage-encoded DNA recognition and terminase protein. The terminase enzymes described so far, which are hetero-oligomers composed of a small and a large subunit, do not have a significant level of sequence homology. The small terminase subunit is thought to form a nucleoprotein structure that helps to position the terminase large subunit at the packaging initiation site.	2.30912e-13
NC_013517.1\|WP_012863320.1\|4162937_4163858_-\|replication-initiator-protein-A	gnl\|CDD\|369151	pfam06970, RepA_N, Replication initiator protein A (RepA) N-terminus. This of family of predicted proteins represents the N-terminus (approximately 80 residues) of replication initiator protein A (RepA), a DNA replication initiator in plasmids. Most proteins in this family are bacterial, but archaeal and eukaryotic members are also included.	1.64121e-14
NC_013517.1\|WP_012863312.1\|4154117_4154687_-\|phage-virion-morphogenesis-protein	gnl\|CDD\|227338	COG5005, COG5005, Mu-like prophage protein gpG [General function prediction only].	1.66914e-11
NC_013517.1\|WP_041310142.1\|4158006_4158462_-\|terminase	gnl\|CDD\|224697	COG1783, XtmB, Phage terminase large subunit [General function prediction only].	2.29171e-35
NC_013517.1\|WP_012863313.1\|4154676_4156863_-\|minor-capsid-protein	gnl\|CDD\|309383	pfam04233, Phage_Mu_F, Phage Mu protein F like protein. Members of this family are found in double-stranded DNA bacteriophages, and in some bacteria. A member of this family is required for viral head morphogenesis in bacteriophage SPP1. This family is possibly a minor head protein. This family may be related to the family TT_ORF1 (pfam02956).	3.22464e-12
NC_013517.1\|WP_012863325.1\|4165527_4166265_-\|Bro-N-domain-containing-protein	gnl\|CDD\|376797	pfam02498, Bro-N, BRO family, N-terminal domain. This family includes the N-terminus of baculovirus BRO and ALI motif proteins. The function of BRO proteins is unknown. It has been suggested that BRO-A and BRO-C are DNA binding proteins that influence host DNA replication and/or transcription. This Pfam domain does not include the characteristic invariant alanine, leucine, isoleucine motif of the ALI proteins.	8.54892e-21
NC_013517.1\|WP_169305423.1\|4161096_4162941_-\|AAA-family-ATPase	gnl\|CDD\|238542	cd01122, GP4d_helicase, GP4d_helicase is a homohexameric 5'-3' helicases. Helicases couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands.	1.03153e-24

>NC_013517.1|WP_012863314.1|4158464_4159394_-|terminase-small-subunit
MAKYEKKDIIKIQKIYENTDISLNKLAKKEGIGKATIIKWSQDYRWAKKEKSDQLPTDQEENRPKNPTEKDSMVGEIEKTEKISFAEEIIEPVLEDVEATKRHTIFTGKEKMFITYYFLYKFNIKAASLAAGYSNEREGNRILRKPKIQKIIRRIKQILIEKAGLDFTKEDLIEELFINLKKATGEIPQVKTFMVDKFDKDTTPITVRTFQGKLEDGTVVEGTEIYGELKEGSFKDVVKNKINENSYQVPEEHLIRDTDLKAANMTAKLLAELFGYTDNSKLAREKFEHEKVKDKEIELEEKIEYVEDV
>NC_013517.1|WP_041310142.1|4158006_4158462_-|terminase
MEIRLSEVIGKGYNTFWNSRQRYRAVKGSRGSKKSRTTALWLIYHIMKYREANALVVRKVFDNLRQSCYSDLEWAINRLGVRHLWKSSKSPLELIFKPTGQKILFRGLDDPLKLTSITVSEGYLCWCWIKKSVQHIKINSSNCWNTLTKLI
>NC_013517.1|WP_012863313.1|4154676_4156863_-|minor-capsid-protein
MFWKNKKPREPSYVTDKRVLQNIARNVIDINSYDIEYRNVYEARELQEIYEYIDINTAVSTLVRGITSRELIFTSENGKINNPEENILIEEGQKRINNIKGKINFIRELAKTPFLKITVHEVIYNDKFEIERLDFIPRELIRYDKEKKLFYIQSKLSEKIYLNNPMKWHVSIYNEDVTKPYGETLLKPILKTYEEIKYIKGKMNGIIEKYGGTIVLFGYNTALEDDEVMKTALELKKMMDGNSVGMPSDGNLKDNLVLLRLADLNVEIHTLLMEKLEKKIFQNILGSTLTLNDGSASGKGTQALGTIHQEEKEKVEDGIALFVREELDKIIDIDGLIHGYDPNQYYIEINRQQDRKKELEIKNLEQDEVNKKADLIVKLSQAGYEIEDTELQEIFGYKTLKKKEQQITNPFTEFSKKNTEDSNKKTLEYLERLRKRIVPDISKKIVNQIKNITSIEDIQNIDTGIKEHENSLILSELWGQYLTIKDRDKVQKKEFASYTPEDFQDIFRMPFNEATNWLLSREPQMYDQIQRVMERYRTNYFWIKRSTDLEVTKILYAELLKNLELGQTFDDFKNNLDIDSLGFGEDGYYLRQVFDQTMINAQSVGHWEQLQEGMQYGFIYGLYDAIIDGRETVICRELDGKIYRLDDPFWMNYYPPNHFKCRSRVIALSEEDLQTYGYSVTTGRPEGEPQKGFTGNIGENYISGIKKQVNQKEKAVNELYEKVTGYEA
>NC_013517.1|WP_012863312.1|4154117_4154687_-|phage-virion-morphogenesis-protein
MKPKFKVVKKLKNLEKRVQAVKNMYDVTFLTAKISKDMEKEVGLRFRNEVDPEGRPWKGLAVSTLNRRQGLTRAQRKVKTRRRRGKTYKEIEAEMGLDKGGASSLFRAGKKRQSTRPKILQDQGYLRGSIKARHTKTEAIVGTSMKYAAVHNFGSPKRKIPQRRFMGLNRGQRIKYKDWIIKWKKGQLR
>NC_013517.1|WP_115388815.1|4153228_4154104_-|hypothetical-protein
MVKIKVFKSGKYPQGEYDKEKVKNIFSKAKDTEAIFLHTSLWAKDETPLNLGKFSNYEFKESGNEVEVFADLELNETGKKFYHGKVLNGVSVELPNDELTKIAILPNKVNPAVEGAEFQESPIFMEFQEIKEDNPPKKEKGEDEKMDRKEVLDTLTKPEIEAQAERLNITVAERLKPKTPEELEQEITARITKEAGDKAKVQEFMKEHDKKIVPAFKPFFEKIVEESLKSEVNWEFNKKDTSLYDGLQEFMKKMPEFSGFKNYSENIEFEEQGTLSNSPFSQGQKVIEGGN
>NC_013517.1|WP_012863310.1|4152849_4153227_-|hypothetical-protein
MSKMGIESVEKKPDYRIIETTRTGTYKAVANITVPDGKLVIVAIDNSDPAIAQIKEYDGTAGDIIAGVIKENAIAGENSVIVKRGKLNIETIDTSNISGLEDYEVFELLEHQNLYVEKLSERQEF
>NC_013517.1|WP_012863309.1|4151838_4152837_-|major-capsid-protein
MDNKIKQILYFVGILSRIEPTEKTFYLDMLKGSKITTPASTIIYDAYVSKYVRAQLIGNDDKTKGNYAGREGYNKFRVTPGKIREYYQLTADDAAYIRAGDIAYFNGKERKAEDSLYENVATYLKNAITSRMDLIVAELLSEGKYFADTGEEIKFDIPSVQTVKKNDVSDFKSFLRIMKEKITEYKRKSFDTPDRILVGEEIVNDLIDDEFFMNQIDKLGLANVMVDDKYVAIAKVFNHLLIESDPIVDMKGADISIAKGNRMTMLATKRLHPAFAGVDVLDSSGMPKKIASEYIMRNDSDVLNATAIFVGESCFTPIISNPKSVVRIDVTK
>NC_013517.1|WP_012863308.1|4151491_4151827_-|hypothetical-protein
MGADYELPQALKDTLERLGYTSEEIDKRIENYSEESRTYVKAELEGFEMTEAEICLIRNNYIQYKLFADVEMDSMVEDKRIFLKDFINSIKKNKLRLQLEKKEKPRRIMVI
>NC_013517.1|WP_012863307.1|4151095_4151491_-|hypothetical-protein
MLEILKKRIEEVSGKNCISGFAADFPYAMLTGNNIIIQPESQESRTIGLNHRKEITRRVKLIYGRFNKLKTGSLEEVEWVEEFLSNLEKDRELLTHIINMDHQYIVGIEKNGENDKTGYVVFQIYLDIKER
>NC_013517.1|WP_012863306.1|4150153_4151092_-|hypothetical-protein
MEVRVLVGVQSGRGTAETSTMYRLASTDFGMAPSVDKTTSEALGSGRWERDGFVSKIAVEGDLPVEATREQLELLFYGAGFDGVADSVDPDLWIITPSNATKNWLTVGMDDIDNDMFEYSKDCLISSINISTSIAAYVTATASMIGMDFTTNSTGYTGTEIAPKGEPLICLGTTIKQNGVDITSKVESIDINIDNKLEGKQSLNSEYYKAIRQGERGSVGISMTFNEFDKPTYIQDLSDIKSNSSYEIITEFAERGNPAKIFRMTFPNCKVTKSERTDIGGAGGLTKEVSAYYDETEKTPVKIEILDYASIL
>NC_013517.1|WP_012863316.1|4159797_4159986_-|hypothetical-protein
MVKNEGFSNYTDEELKRLREHDLSLIKTLRKERKSMMEDIKIITLRKKSVREELIKRGMFKK
>NC_013517.1|WP_012863317.1|4160003_4160810_-|hypothetical-protein
MSKILSISDKKKKKLTIDERLEHTLNMLNKLMAEGVFTKKGESQIMKMAEDVKTILGCPDKSIRKSWVVACDSERGKAKIPEYKHITLLGDFGHENEEMHKLFELEKMVLWELHGNLNGKKCTIKDLKGNILKNGAIELLFSENEDRVEYGIRILLDGEILRDIAFNEFFYVTADHESFEVEVLNGDDRFQIEAEILISNEDTVFYTECLSRRMKMMREYMTPEQNEKFDNMTINCLSDIIESDIGVKPEIEKEGDFIKVTTEEPTIN
>NC_013517.1|WP_012863318.1|4160822_4161092_-|hypothetical-protein
MELDEALKVLKRAIRKIKEYETGKVQENLIVEGKNFKGWYIQAYKNKQLDLKFFTGWIKINNVFEEFVKENKMESINGLNKILQEFGEE
>NC_013517.1|WP_169305423.1|4161096_4162941_-|AAA-family-ATPase
MILGKETMNIEDFIKEHLGEYRIKGKEAVIRICPFCGRDKNKFYMNIETGLYNCFSGSCGEKGTIETLMKHLGINQKVKKKPVEKSEIRNTEKIELNRENYSSIGVLKENKIISKKQAEFLENRGISWETAAEMDVWVRRSDGWLTFIYRNKKRVLAVKYRDINKKDFRLTKSEDINPLFNIHRVTGESVIICEGEMDVLACAEVGMKDKAVSVPNGTNNLGWIEYNWDFLESKKEIILAFDNDTAGEKAIKEVLKRLDITKCRYLDMKGEKDLNDILINLGKVELLNILNNPLEFEIEGLQDITNEKMDTGSTEAIFFEMESLDKQFGGCRFGELTIVSGQPGAGKSTILNQIICDFVNQDEKVFYYSGEFPKAKAKRWLYTVFAGADSLTEEYDKHKRRNKYVLKPGIERQIDNWAKNKIFIYDKGTEAKQNELFTIMKYGYKKHGIRLFFLDNLMTIGLDEVNDDKYENQKNFLTELHDFAIEYNVHVFLVAHPKKTENKKIQDLSFYDIAGSSNIPNLADNILFMKRLNEKEKEEMYNKMGHNYTTAAILLKDREYGEMGTTSFFGFQYTARRFFNPETKIEIRKKYRWVENLRKLNDEDLEEIEKLLGV
>NC_013517.1|WP_012863320.1|4162937_4163858_-|replication-initiator-protein-A
MRNIKSNDLSNMIYYQVPKWLMDLFIDKKISQGAFKTYILMYDRLKLSAGNKWIDKNGDVYIKYSYDEMTEDLNCSRQAVSNNLQDLEKLDLIDKKKNFSSSSTFYLKIYSKENDNSQEKFTSQEDFTSEENLDCRESTKLDCSSQENLDANKNNSNNNKYNKNNNKEKFQNLENKNSSTEDEDASHIDEVIYNISVVNRIRQINKNQVEGDQILRIFLEKKILEELVLWILDFLEMRSKGEKIYIQEVRSVVNQLINKYSSDEIRIKALEHAIASRHNSIVYEEKQGKTGDEKTGSFLDGIKIIN
>NC_013517.1|WP_012863321.1|4164149_4164710_-|hypothetical-protein
MNREFLESLFDETYEIVYANSEEAIMLRRKIVEKIEILKSKEITKISIFDLNLQGLVTDKLQSFFMGNINIFKEIYGLDEDNKAEMITALKNHSEKIVNDFIDNAPTYESNLKEFIELKEKFRPELNEKKRAVFKEYEDLQTEREAFILELKFEVMLKISEFLYNIDKIKKIDFMIEKKTPEETEV
>NC_013517.1|WP_012863324.1|4164988_4165510_-|hypothetical-protein
MDNKKIESLLNITYEILLDQNKNIEKSEKKLSELEETLSGNDENFFILRGLSGSMVSALQETKKDYFLNHINDFIGVNNLSLEIKEYALKKISGNCDDETESIRGNLKYNESSTESKKLEKEMKEKFSGEENTVFEIYLELLVDIQSEENLLFYEAMLQTGAYLNKIEEITEV
>NC_013517.1|WP_012863325.1|4165527_4166265_-|Bro-N-domain-containing-protein
MNNLIVKNEKFGQLEIYVDEKGKVWFPATEVAEMLGYKNPHKAILDHCKEHGVTFREVIANTGFGDSKQKKKYIDEGNVFRLITKSHIPGAEEFESWIFDEAIPQIMKTGKYEIKAPKNKILDQEIKLKNSRSRMANAYLKIANNTALPNEYRQVMLTYAANELSGTDILPLPSSEKRTFTATEIGEKLGISANKVGALTNTHDLKTDEFGKFVWDKSPYSPKQVETFRYYENIIPVLEEILKEI
>NC_013517.1|WP_012863326.1|4166257_4166482_-|hypothetical-protein
MWWWIKIHIIEGWADMVRWFNNRKKLLEEIKLQEKYIKALEDELRRYLEAPESRVIAFKSGKNRRVITRRNRYE
>NC_013517.1|WP_012863327.1|4166450_4166858_-|hypothetical-protein
MSEERTEAECFEILYERIKGINAKDIYNKIIPIFVTFAGEEPPVSMSKKYIERDYLEVSIVMVEFIHCMTYGIDFPTFKDNDKEFDKIKVKNKALWHLIKLKAEMYGKEILEENGLELIDKVGENYVVVDKNTYN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_013517_5	5.3\|1415744\|34\|NC_013517\|PILER-CR,CRT	1415744-1415777	34	NZ_CP010107	Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-1, complete sequence	3820-3853	7	0.794
NC_013517_6	6.1\|1817365\|36\|NC_013517\|CRISPRCasFinder	1817365-1817400	36	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	561317-561352	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP011282	Enterococcus faecium strain E39 plasmid p1, complete sequence	111991-112026	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP018832	Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence	166656-166691	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP018073	Enterococcus faecium strain VRE001 plasmid unnamed3, complete sequence	81659-81694	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP025756	Enterococcus faecium strain AALTL plasmid pEFA-99d7, complete sequence	49464-49499	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP017798	Enterococcus faecium strain E243 plasmid unnamed1, complete sequence	129344-129379	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NC_021987	Enterococcus faecium Aus0085 plasmid p1, complete sequence	62654-62689	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP017793	Enterococcus faecium strain E240 plasmid unnamed1, complete sequence	129344-129379	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP023790	Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence	158618-158653	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP023800	Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence	162090-162125	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_LR135308	Enterococcus faecium isolate E7240 plasmid 2	125164-125199	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP023809	Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence	162103-162138	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP023805	Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence	160757-160792	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NC_020208	Enterococcus faecium ATCC 8459 = NRRL B-2354 plasmid pNB2354_1, complete sequence	147367-147402	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP034948	Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence	118502-118537	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP018827	Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence	166656-166691	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP023795	Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence	162103-162138	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP023781	Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence	159426-159461	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP041256	Enterococcus faecium strain 515 plasmid p26, complete sequence	24615-24650	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_LN999988	Enterococcus faecium isolate EFE11651 plasmid II, complete sequence	154555-154590	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP034947	Enterococcus faecium strain NM213 plasmid unnamed4, complete sequence	12002-12037	8	0.778
NC_013517_7	7.1\|2840178\|36\|NC_013517\|CRISPRCasFinder	2840178-2840213	36	NZ_CP012461	Enterococcus faecium strain ISMMS_VRE_7 plasmid ISMMS_VRE7_p1, complete sequence	69435-69470	8	0.778
NC_013517_7	7.2\|2840244\|37\|NC_013517\|CRISPRCasFinder	2840244-2840280	37	LR596903	Roseburia phage Shimadzu genome assembly, chromosome: 1	34071-34107	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP041256	Enterococcus faecium strain 515 plasmid p26, complete sequence	24614-24650	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_LN999988	Enterococcus faecium isolate EFE11651 plasmid II, complete sequence	154554-154590	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP034947	Enterococcus faecium strain NM213 plasmid unnamed4, complete sequence	12001-12037	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP012461	Enterococcus faecium strain ISMMS_VRE_7 plasmid ISMMS_VRE7_p1, complete sequence	69434-69470	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP011282	Enterococcus faecium strain E39 plasmid p1, complete sequence	111991-112027	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP018832	Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence	166656-166692	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP018073	Enterococcus faecium strain VRE001 plasmid unnamed3, complete sequence	81659-81695	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP025756	Enterococcus faecium strain AALTL plasmid pEFA-99d7, complete sequence	49464-49500	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP017798	Enterococcus faecium strain E243 plasmid unnamed1, complete sequence	129344-129380	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NC_021987	Enterococcus faecium Aus0085 plasmid p1, complete sequence	62654-62690	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP017793	Enterococcus faecium strain E240 plasmid unnamed1, complete sequence	129344-129380	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP023790	Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence	158618-158654	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP023800	Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence	162090-162126	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_LR135308	Enterococcus faecium isolate E7240 plasmid 2	125164-125200	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP023809	Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence	162103-162139	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP023805	Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence	160757-160793	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NC_020208	Enterococcus faecium ATCC 8459 = NRRL B-2354 plasmid pNB2354_1, complete sequence	147367-147403	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP034948	Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence	118502-118538	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP018827	Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence	166656-166692	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP023795	Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence	162103-162139	9	0.757
NC_013517_7	7.3\|2840185\|37\|NC_013517\|PILER-CR	2840185-2840221	37	NZ_CP023781	Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence	159426-159462	9	0.757
NC_013517_7	7.4\|2840251\|38\|NC_013517\|PILER-CR	2840251-2840288	38	LR596903	Roseburia phage Shimadzu genome assembly, chromosome: 1	34071-34108	9	0.763
NC_013517_6	6.2\|1817431\|37\|NC_013517\|CRISPRCasFinder	1817431-1817467	37	KT997868	Uncultured Mediterranean phage uvDeep-CGR2-KM24-C165, complete genome	9781-9817	10	0.73

1. spacer 5.3|1415744|34|NC_013517|PILER-CR,CRT matches to NZ_CP010107 (Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-1, complete sequence) position: , mismatch: 7, identity: 0.794

ttttctaattcttccgcaactattatagttttat	CRISPR spacer
ttttctaattcttccgcaactatttttctcactt	Protospacer
************************ *  *. . *

2. spacer 6.1|1817365|36|NC_013517|CRISPRCasFinder matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 8, identity: 0.778

atgttatattttttatcattttatcatctccttaat	CRISPR spacer
aattagaacttattctcattttatcatctccttaat	Protospacer
*  * . *.** ** *********************

3. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP011282 (Enterococcus faecium strain E39 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

4. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP018832 (Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

5. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP018073 (Enterococcus faecium strain VRE001 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

6. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP025756 (Enterococcus faecium strain AALTL plasmid pEFA-99d7, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

7. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP017798 (Enterococcus faecium strain E243 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

8. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NC_021987 (Enterococcus faecium Aus0085 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

9. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP017793 (Enterococcus faecium strain E240 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

10. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP023790 (Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

11. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP023800 (Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

12. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_LR135308 (Enterococcus faecium isolate E7240 plasmid 2) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

13. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP023809 (Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

14. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP023805 (Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

15. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NC_020208 (Enterococcus faecium ATCC 8459 = NRRL B-2354 plasmid pNB2354_1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

16. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP034948 (Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

17. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP018827 (Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

18. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP023795 (Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

19. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP023781 (Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

20. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP041256 (Enterococcus faecium strain 515 plasmid p26, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

21. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_LN999988 (Enterococcus faecium isolate EFE11651 plasmid II, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

22. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP034947 (Enterococcus faecium strain NM213 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

23. spacer 7.1|2840178|36|NC_013517|CRISPRCasFinder matches to NZ_CP012461 (Enterococcus faecium strain ISMMS_VRE_7 plasmid ISMMS_VRE7_p1, complete sequence) position: , mismatch: 8, identity: 0.778

aaaactcaatcaaaatagggtgtcaaaagtacactc	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacacta	Protospacer
* ** *.  *********** ******* ******

24. spacer 7.2|2840244|37|NC_013517|CRISPRCasFinder matches to LR596903 (Roseburia phage Shimadzu genome assembly, chromosome: 1) position: , mismatch: 9, identity: 0.757

ctgttaaatccatgttataatatattatctttttgaa	CRISPR spacer
cgcgtggacctatgctataaaatattatctttttgaa	Protospacer
*   *..*.*.***.***** ****************

25. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP041256 (Enterococcus faecium strain 515 plasmid p26, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

26. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_LN999988 (Enterococcus faecium isolate EFE11651 plasmid II, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

27. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP034947 (Enterococcus faecium strain NM213 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

28. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP012461 (Enterococcus faecium strain ISMMS_VRE_7 plasmid ISMMS_VRE7_p1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

29. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP011282 (Enterococcus faecium strain E39 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

30. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP018832 (Enterococcus faecium strain ISMMS_VRE_9 plasmid p1_ISMMS_VRE9, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

31. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP018073 (Enterococcus faecium strain VRE001 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

32. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP025756 (Enterococcus faecium strain AALTL plasmid pEFA-99d7, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

33. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP017798 (Enterococcus faecium strain E243 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

34. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NC_021987 (Enterococcus faecium Aus0085 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

35. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP017793 (Enterococcus faecium strain E240 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

36. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP023790 (Enterococcus faecium strain Efaecium_ER04462.3A plasmid pER04462.3A.1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

37. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP023800 (Enterococcus faecium strain Efaecium_ER04526.5A plasmid pER04526.5A.1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

38. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_LR135308 (Enterococcus faecium isolate E7240 plasmid 2) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

39. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP023809 (Enterococcus faecium strain Efaecium_ER04526.3A plasmid pER04562.3A.1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

40. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP023805 (Enterococcus faecium strain Efaecium_ER04619.3A isolate isolate plasmid pER04619.3A.1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

41. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NC_020208 (Enterococcus faecium ATCC 8459 = NRRL B-2354 plasmid pNB2354_1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

42. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP034948 (Enterococcus faecium strain NM213 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

43. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP018827 (Enterococcus faecium strain ISMMS_VRE_12 plasmid p1_ISMMS_VRE12, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

44. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP023795 (Enterococcus faecium strain Efaecium_ER04484.3A plasmid pER04484.3A.1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

45. spacer 7.3|2840185|37|NC_013517|PILER-CR matches to NZ_CP023781 (Enterococcus faecium strain Efaecium_ER03933.3A isolate isolate plasmid pER93933.3A.1, complete sequence) position: , mismatch: 9, identity: 0.757

aaaactcaatcaaaatagggtgtcaaaagtacactca	CRISPR spacer
ataaattcttcaaaatagggagtcaaaactacactac	Protospacer
* ** *.  *********** ******* ******

46. spacer 7.4|2840251|38|NC_013517|PILER-CR matches to LR596903 (Roseburia phage Shimadzu genome assembly, chromosome: 1) position: , mismatch: 9, identity: 0.763

ctgttaaatccatgttataatatattatctttttgaaa	CRISPR spacer
cgcgtggacctatgctataaaatattatctttttgaaa	Protospacer
*   *..*.*.***.***** *****************

47. spacer 6.2|1817431|37|NC_013517|CRISPRCasFinder matches to KT997868 (Uncultured Mediterranean phage uvDeep-CGR2-KM24-C165, complete genome) position: , mismatch: 10, identity: 0.73

taatattaccacctttttttagtttttgtgtttcatc	CRISPR spacer
gactaaaaccaccttgttttagttgttgtgtttgtgt	Protospacer
 * **  ******** ******** ********   .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

879272 : 891929

Clostridium_phage(20.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012860263.1\|879272_880763_-	recombinase family protein	A0A0A7RTP8	Clostridium_phage	4.6e-68	39.0
WP_012860265.1\|880888_881146_-	hypothetical protein	NA	NA	NA	NA
WP_012860266.1\|881142_881394_-	hypothetical protein	NA	NA	NA	NA
WP_012860267.1\|881395_881740_-	hypothetical protein	NA	NA	NA	NA
WP_012860268.1\|881833_882100_-	hypothetical protein	NA	NA	NA	NA
WP_012860269.1\|882111_882396_-	hypothetical protein	NA	NA	NA	NA
WP_012860270.1\|882474_882681_-	hypothetical protein	NA	NA	NA	NA
WP_012860271.1\|882692_882971_-	hypothetical protein	NA	NA	NA	NA
WP_012860272.1\|882967_883438_-	hypothetical protein	NA	NA	NA	NA
WP_012860273.1\|883439_883643_-	hypothetical protein	NA	NA	NA	NA
WP_012860274.1\|883644_884025_-	hypothetical protein	R4JMS5	Bacillus_phage	4.0e-08	30.0
WP_012860275.1\|884025_884286_-	hypothetical protein	NA	NA	NA	NA
WP_012860276.1\|884282_884627_-	hypothetical protein	A8ASN9	Listeria_phage	1.2e-16	46.0
WP_012860277.1\|884616_884772_-	hypothetical protein	NA	NA	NA	NA
WP_012860278.1\|884780_885050_-	hypothetical protein	NA	NA	NA	NA
WP_012860279.1\|885087_885924_-	hypothetical protein	H7BVI6	unidentified_phage	1.1e-26	50.7
WP_012860280.1\|885932_886208_-	hypothetical protein	NA	NA	NA	NA
WP_012860281.1\|886255_886633_-	single-stranded DNA-binding protein	A0A218KCM4	Bacillus_phage	7.7e-20	42.6
WP_012860282.1\|886632_887247_-	ERF family protein	A0A090D840	Clostridium_phage	2.5e-36	45.5
WP_115388830.1\|887362_887989_-	phage antirepressor N-terminal domain-containing protein	A5VW58	Enterobacteria_phage	1.2e-09	28.3
WP_012860284.1\|888146_888356_+	helix-turn-helix transcriptional regulator	Q331Y7	Clostridium_botulinum_C_phage	1.5e-12	50.7
WP_049768968.1\|888645_889383_-	phage antirepressor KilAC domain-containing protein	Q331V6	Clostridium_botulinum_C_phage	1.8e-28	39.0
WP_012860287.1\|889584_890304_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_012860288.1\|890319_890520_-	hypothetical protein	NA	NA	NA	NA
WP_012860289.1\|890520_890808_-	hypothetical protein	NA	NA	NA	NA
WP_012860290.1\|891015_891480_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_041309795.1\|891494_891929_+	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	1.8e-17	37.9

DBSCAN-SWA_2

907152 : 914375

Clostridium_phage(16.67%)

terminase,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012860318.1\|907152_907452_+	hypothetical protein	A0A0A7RTF2	Clostridium_phage	1.5e-05	34.7
WP_012860319.1\|907452_908145_+	antA/AntB antirepressor family protein	A0A2D1GPQ2	Lactobacillus_phage	5.0e-17	42.4
WP_012860320.1\|908167_909043_+\|terminase	terminase small subunit	A0A0S2MVB6	Bacillus_phage	3.6e-20	29.3
WP_012860321.1\|909020_910520_+	hypothetical protein	B6SBS6	Clostridium_virus	3.3e-37	28.5
WP_012860322.1\|910532_911753_+	hypothetical protein	NA	NA	NA	NA
WP_012860323.1\|911745_912306_+	hypothetical protein	A0A0E3Y641	Fusobacterium_phage	8.2e-10	39.0
WP_012860324.1\|912319_912925_+	hypothetical protein	NA	NA	NA	NA
WP_012860325.1\|912939_913311_+	hypothetical protein	NA	NA	NA	NA
WP_012860326.1\|913322_914375_+\|capsid	major capsid protein	A0A2D1GQD3	Lysinibacillus_phage	3.0e-13	25.8

DBSCAN-SWA_3

924676 : 984927

Bacteriophage(25.0%)

tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012860342.1\|924676_925843_+\|plate	baseplate J/gp47 family protein	NA	NA	NA	NA
WP_012860343.1\|925835_926477_+	hypothetical protein	NA	NA	NA	NA
WP_012860344.1\|926476_927325_+	hypothetical protein	NA	NA	NA	NA
WP_012860345.1\|927333_927786_+	hypothetical protein	NA	NA	NA	NA
WP_012860346.1\|927782_928442_+	N-acetylmuramoyl-L-alanine amidase	B6RT63	Bacillus_virus	2.4e-08	31.8
WP_012860347.1\|928450_928783_+	hypothetical protein	NA	NA	NA	NA
WP_012860348.1\|928800_929025_+	excalibur calcium-binding domain-containing protein	NA	NA	NA	NA
WP_012860349.1\|929021_929615_+	hypothetical protein	NA	NA	NA	NA
WP_012860350.1\|929636_929834_-	hypothetical protein	NA	NA	NA	NA
WP_147289468.1\|931503_931767_+	hypothetical protein	NA	NA	NA	NA
WP_012860351.1\|932423_932972_+	hypothetical protein	NA	NA	NA	NA
WP_012860352.1\|933059_933578_+	hypothetical protein	NA	NA	NA	NA
WP_012860353.1\|935076_935478_-	hypothetical protein	NA	NA	NA	NA
WP_012860355.1\|936037_936223_+	hypothetical protein	NA	NA	NA	NA
WP_012860356.1\|936180_936414_+	hypothetical protein	NA	NA	NA	NA
WP_012860357.1\|936489_936717_+	hypothetical protein	NA	NA	NA	NA
WP_012860358.1\|936815_937808_+	SEL1-like repeat protein	NA	NA	NA	NA
WP_012860359.1\|937861_938593_+	hypothetical protein	E3W8D3	Leuconostoc_phage	8.8e-12	25.1
WP_012860360.1\|938686_939322_+	hypothetical protein	NA	NA	NA	NA
WP_012860361.1\|939425_940190_+	DKNYY domain-containing protein	NA	NA	NA	NA
WP_012860362.1\|940307_940697_+	DKNYY domain-containing protein	NA	NA	NA	NA
WP_012860363.1\|940693_941179_+	hypothetical protein	NA	NA	NA	NA
WP_115388747.1\|941505_941676_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_169305424.1\|942008_942197_-	hypothetical protein	NA	NA	NA	NA
WP_169305388.1\|942434_943268_-	hypothetical protein	NA	NA	NA	NA
WP_012860364.1\|943633_943885_+	hypothetical protein	NA	NA	NA	NA
WP_041309803.1\|943915_944719_-	YdcF family protein	NA	NA	NA	NA
WP_012860366.1\|945344_952421_+	autotransporter domain-containing protein	NA	NA	NA	NA
WP_012860367.1\|952625_953471_+	hypothetical protein	NA	NA	NA	NA
WP_012860368.1\|953586_954084_-	hypothetical protein	NA	NA	NA	NA
WP_012860369.1\|954284_955076_+	HAD family hydrolase	NA	NA	NA	NA
WP_012860370.1\|955320_955833_+	small multi-drug export protein	NA	NA	NA	NA
WP_012860371.1\|956184_958881_+	calcium-translocating P-type ATPase, PMCA-type	A0A1J0FA34	Only_Syngen_Nebraska_virus	1.5e-96	31.8
WP_012860372.1\|959550_961074_+	DUF1538 domain-containing protein	NA	NA	NA	NA
WP_012860373.1\|961073_961796_+	hypothetical protein	NA	NA	NA	NA
WP_012860374.1\|961829_962507_+	hypothetical protein	NA	NA	NA	NA
WP_012860375.1\|962994_963984_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-14	27.3
WP_012860376.1\|963976_964837_+	ABC-2 family transporter protein	NA	NA	NA	NA
WP_012860377.1\|964833_965628_+	ABC-2 family transporter protein	NA	NA	NA	NA
WP_012860378.1\|965949_966885_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_147289470.1\|967051_967234_+	hypothetical protein	NA	NA	NA	NA
WP_147289471.1\|967448_968180_+	hypothetical protein	NA	NA	NA	NA
WP_012860381.1\|968805_969579_+	hypothetical protein	NA	NA	NA	NA
WP_012860382.1\|969674_970226_+	hypothetical protein	NA	NA	NA	NA
WP_041309804.1\|970286_970526_+	hypothetical protein	NA	NA	NA	NA
WP_041309806.1\|970619_971054_+	hypothetical protein	NA	NA	NA	NA
WP_012860384.1\|971427_972099_+	porin family protein	NA	NA	NA	NA
WP_012860385.1\|973029_973503_+	hypothetical protein	NA	NA	NA	NA
WP_012860386.1\|973495_973771_+	hypothetical protein	NA	NA	NA	NA
WP_012860387.1\|973770_975201_+	hypothetical protein	A0A0E3U251	Fusobacterium_phage	8.3e-83	37.2
WP_012860388.1\|975213_975735_+\|tail	phage major tail tube protein	Q75QK9	Wolbachia_phage	4.6e-07	27.7
WP_012860389.1\|975801_976077_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_012860390.1\|976260_978144_+	hypothetical protein	NA	NA	NA	NA
WP_012860391.1\|978136_978349_+	hypothetical protein	NA	NA	NA	NA
WP_012860392.1\|978358_979447_+	Phage protein D-like protein	A0A067ZG47	Vibrio_phage	1.6e-38	29.3
WP_012860393.1\|979443_979977_+\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	7.0e-19	40.5
WP_012860394.1\|979997_980498_+\|tail	phage tail protein	NA	NA	NA	NA
WP_012860395.1\|980490_980808_+	hypothetical protein	NA	NA	NA	NA
WP_012860396.1\|980804_981914_+\|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	1.9e-66	39.3
WP_012860397.1\|981910_982552_+\|tail	phage tail protein	A0A0C5AJ63	Bacteriophage	8.5e-27	36.4
WP_012860398.1\|982597_983734_+\|tail	phage tail protein	A0A2K9V3P4	Faecalibacterium_phage	5.5e-05	27.7
WP_012860399.1\|983745_984927_+\|tail	phage tail protein	A0A0C5AEQ0	Bacteriophage	2.3e-17	30.4

DBSCAN-SWA_4

1468847 : 1519223

Clostridium_phage(46.67%)

tail,capsid,integrase,plate,tRNA,portal,terminase

attL 1478389:1478407|attR 1520259:1520277

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012860839.1\|1468847_1469183_+\|tRNA	tRNA-binding protein	NA	NA	NA	NA
WP_012860840.1\|1469219_1469747_+	DUF4303 domain-containing protein	NA	NA	NA	NA
WP_012860841.1\|1469838_1472412_-	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	1.7e-118	35.9
WP_012860842.1\|1472832_1474878_+	BglG family transcription antiterminator	NA	NA	NA	NA
WP_012860843.1\|1476827_1477973_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_012860844.1\|1478063_1478222_-	hypothetical protein	NA	NA	NA	NA
1478389:1478407	attL	NA	NA	NA	NA
WP_012860845.1\|1478583_1479618_-\|integrase	site-specific integrase	A0A0E3Y5J2	Fusobacterium_phage	7.9e-59	40.3
WP_012860846.1\|1479742_1480357_-	hypothetical protein	NA	NA	NA	NA
WP_012860847.1\|1480367_1480829_-	ImmA/IrrE family metallo-endopeptidase	S6B1N5	Thermus_phage	2.4e-15	38.2
WP_012860848.1\|1480848_1481277_-	helix-turn-helix transcriptional regulator	A0A0A7RTR3	Clostridium_phage	9.0e-17	50.0
WP_012860849.1\|1481448_1481676_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012860850.1\|1481696_1481909_+	hypothetical protein	NA	NA	NA	NA
WP_012860851.1\|1481962_1482535_-	hypothetical protein	NA	NA	NA	NA
WP_012860852.1\|1482856_1483072_-	hypothetical protein	NA	NA	NA	NA
WP_012860853.1\|1483145_1483475_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012860854.1\|1483485_1483713_+	DNA-binding protein	NA	NA	NA	NA
WP_012860856.1\|1483843_1484017_+	hypothetical protein	NA	NA	NA	NA
WP_012860857.1\|1484016_1484271_+	hypothetical protein	NA	NA	NA	NA
WP_012860858.1\|1484270_1484450_+	hypothetical protein	NA	NA	NA	NA
WP_012860859.1\|1484461_1484614_+	hypothetical protein	NA	NA	NA	NA
WP_012860860.1\|1484622_1484949_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012860861.1\|1484953_1485163_+	hypothetical protein	NA	NA	NA	NA
WP_012860862.1\|1485167_1485365_+	hypothetical protein	NA	NA	NA	NA
WP_012860863.1\|1485354_1485660_+	hypothetical protein	NA	NA	NA	NA
WP_012860864.1\|1485647_1485902_+	hypothetical protein	NA	NA	NA	NA
WP_012860865.1\|1485972_1486134_+	hypothetical protein	NA	NA	NA	NA
WP_012860866.1\|1486302_1486854_+	hypothetical protein	NA	NA	NA	NA
WP_012860867.1\|1486934_1487360_+	hypothetical protein	NA	NA	NA	NA
WP_012860868.1\|1487359_1488529_+	DUF2800 domain-containing protein	S5MUB5	Brevibacillus_phage	1.2e-79	44.9
WP_012860869.1\|1488548_1489136_+	DUF2815 family protein	A0A0A7RVM4	Clostridium_phage	5.2e-31	42.8
WP_012860870.1\|1491386_1491614_+	hypothetical protein	NA	NA	NA	NA
WP_041309856.1\|1491630_1491810_+	hypothetical protein	NA	NA	NA	NA
WP_012860871.1\|1491810_1494231_+	virulence-associated protein E	A0A0A7RTG3	Clostridium_phage	5.4e-191	43.0
WP_012860872.1\|1494718_1495051_+	VRR-NUC domain-containing protein	A0A1W6JQA8	Corynebacterium_phage	3.8e-15	46.2
WP_012860873.1\|1495031_1496408_+	DEAD/DEAH box helicase	S5MA26	Brevibacillus_phage	2.1e-139	52.1
WP_012860874.1\|1496413_1496695_+	hypothetical protein	NA	NA	NA	NA
WP_081439687.1\|1496746_1497235_+	hypothetical protein	NA	NA	NA	NA
WP_012860876.1\|1497234_1497441_+	hypothetical protein	NA	NA	NA	NA
WP_012860877.1\|1497437_1497584_+	hypothetical protein	NA	NA	NA	NA
WP_012860878.1\|1497583_1497808_+	hypothetical protein	NA	NA	NA	NA
WP_012860879.1\|1497812_1498256_+	hypothetical protein	NA	NA	NA	NA
WP_012860880.1\|1498237_1498402_+	hypothetical protein	NA	NA	NA	NA
WP_012860881.1\|1498385_1498913_+	hypothetical protein	NA	NA	NA	NA
WP_012860882.1\|1499231_1499504_+	hypothetical protein	NA	NA	NA	NA
WP_012860883.1\|1499549_1499990_+\|terminase	terminase small subunit	S5MA50	Brevibacillus_phage	7.8e-32	51.4
WP_012860884.1\|1499973_1501266_+\|terminase	PBSX family phage terminase large subunit	A0A0M4R5F3	Bacillus_phage	2.9e-143	59.7
WP_012860885.1\|1501275_1502727_+\|portal	phage portal protein	A0A0A7S074	Clostridium_phage	2.4e-109	45.6
WP_012860886.1\|1502713_1504639_+\|capsid	minor capsid protein	X5JAI9	Clostridium_phage	1.2e-97	41.6
WP_012860887.1\|1504638_1504845_+	hypothetical protein	NA	NA	NA	NA
WP_012860888.1\|1504982_1505585_+	minor structural GP20 protein	S5MUG0	Brevibacillus_phage	2.3e-18	40.9
WP_012860889.1\|1505602_1506676_+	hypothetical protein	A0A0A7RTH8	Clostridium_phage	3.1e-138	68.6
WP_012860890.1\|1506694_1507087_+	hypothetical protein	NA	NA	NA	NA
WP_012860891.1\|1507080_1507440_+	hypothetical protein	A0A0A7S083	Clostridium_phage	2.3e-13	42.1
WP_012860892.1\|1507440_1507890_+	HK97 gp10 family phage protein	X5JB35	Clostridium_phage	5.0e-18	36.9
WP_012860893.1\|1507889_1508324_+	hypothetical protein	A0A0A8WJT3	Clostridium_phage	6.6e-15	36.4
WP_012860894.1\|1508326_1508518_+	hypothetical protein	NA	NA	NA	NA
WP_012860895.1\|1508527_1509835_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A8WIF0	Clostridium_phage	8.9e-140	56.4
WP_012860896.1\|1509852_1510332_+\|tail	phage tail tube protein	A0A0A8WJ62	Clostridium_phage	9.4e-47	57.8
WP_012860897.1\|1510357_1510777_+	XkdN-like protein	S6B9X5	Thermus_phage	3.6e-10	33.6
WP_012860899.1\|1510958_1513079_+	tape measure protein	H7BVH2	unidentified_phage	5.6e-59	31.7
WP_169305393.1\|1513150_1513726_+	hypothetical protein	A0A0A8WFE5	Clostridium_phage	6.4e-26	43.9
WP_012860901.1\|1513712_1514825_+	hypothetical protein	H7BVH4	unidentified_phage	3.0e-72	45.4
WP_012860902.1\|1514821_1515262_+	DUF2577 domain-containing protein	S5MC71	Brevibacillus_phage	1.6e-05	28.1
WP_012860903.1\|1515261_1515672_+	DUF2634 domain-containing protein	A0A0A8WFW6	Clostridium_phage	3.2e-27	47.2
WP_012860904.1\|1515671_1516763_+\|plate	baseplate J/gp47 family protein	A0A0A8WJT7	Clostridium_phage	4.1e-82	44.3
WP_012860905.1\|1516759_1517392_+	DUF2313 domain-containing protein	H7BVG1	unidentified_phage	6.0e-25	38.4
WP_012860906.1\|1517393_1518212_+	hypothetical protein	H7BVG0	unidentified_phage	7.2e-23	43.8
WP_012860907.1\|1518220_1518661_+	hypothetical protein	NA	NA	NA	NA
WP_012860908.1\|1518665_1519223_+	N-acetylmuramoyl-L-alanine amidase	D6QWL7	uncultured_phage	3.8e-23	43.2
1520259:1520277	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2237537 : 2243292

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012861555.1\|2237537_2238017_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	4.8e-27	45.1
WP_012861556.1\|2238039_2238747_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	1.2e-42	43.9
WP_012861557.1\|2238749_2240177_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.2e-52	31.9
WP_012861558.1\|2240163_2241159_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FC27	Synechococcus_phage	2.9e-66	43.1
WP_012861559.1\|2241146_2241716_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.0e-21	33.7
WP_012861560.1\|2241789_2243292_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.1e-64	46.2

DBSCAN-SWA_6

2459239 : 2467331

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012861771.1\|2459239_2460733_-	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	3.5e-31	34.2
WP_012861772.1\|2460781_2461453_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.0e-43	40.6
WP_012861773.1\|2461548_2462253_-	DNA/RNA nuclease SfsA	A0A127AYZ0	Bacillus_phage	7.1e-11	29.8
WP_012861774.1\|2462367_2463066_-	ribonuclease PH	NA	NA	NA	NA
WP_012861775.1\|2463082_2464324_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	2.2e-100	51.2
WP_012861776.1\|2464572_2464887_-	hypothetical protein	NA	NA	NA	NA
WP_012861777.1\|2465198_2466425_-	competence/damage-inducible protein A	B5TK85	Pseudomonas_phage	2.9e-15	36.2
WP_012861778.1\|2466557_2467331_-	SDR family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.3e-09	22.2

DBSCAN-SWA_7

2659021 : 2685693

Vibrio_phage(25.0%)

tail,tRNA,portal,terminase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081439690.1\|2659021_2659210_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.8e-07	48.3
WP_012861925.1\|2659562_2659826_-	hypothetical protein	NA	NA	NA	NA
WP_081439626.1\|2660135_2660375_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_012861927.1\|2660852_2661461_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_012861928.1\|2661457_2661949_-	N-acetyltransferase	NA	NA	NA	NA
WP_012861929.1\|2661971_2662466_-	dCMP deaminase family protein	A0A2R8FFD0	Brazilian_cedratvirus	6.9e-45	52.2
WP_012861930.1\|2662511_2663900_-\|tRNA	asparagine--tRNA ligase	A0A167RLM0	Powai_lake_megavirus	1.4e-87	38.0
WP_012861931.1\|2664102_2664549_-	hypothetical protein	NA	NA	NA	NA
WP_012861932.1\|2664587_2664791_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_012861933.1\|2664894_2665626_-	SIS domain-containing protein	NA	NA	NA	NA
WP_012861934.1\|2665640_2666372_-	creatininase family protein	NA	NA	NA	NA
WP_012861935.1\|2666477_2667470_-	phosphotriesterase	NA	NA	NA	NA
WP_041310804.1\|2667490_2668786_-	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_012861937.1\|2668844_2669114_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_012861938.1\|2669113_2669548_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_012861939.1\|2669767_2670865_+	replication initiation protein	NA	NA	NA	NA
WP_012861940.1\|2670896_2672519_-	chaperonin GroEL	A0A240F779	uncultured_virus	1.1e-160	57.6
WP_012861941.1\|2672538_2672802_-	co-chaperone GroES	A0A221S322	uncultured_virus	7.2e-09	38.9
WP_012861942.1\|2673709_2673937_-	hypothetical protein	NA	NA	NA	NA
WP_012861943.1\|2673948_2674155_-	hypothetical protein	NA	NA	NA	NA
WP_012861944.1\|2674151_2674430_-	hypothetical protein	NA	NA	NA	NA
WP_012861945.1\|2674554_2674842_-	hypothetical protein	NA	NA	NA	NA
WP_012861946.1\|2675037_2675547_+	DUF4189 domain-containing protein	NA	NA	NA	NA
WP_012861947.1\|2675603_2675975_-	hypothetical protein	NA	NA	NA	NA
WP_012861948.1\|2676376_2676670_-	hypothetical protein	NA	NA	NA	NA
WP_012861949.1\|2676698_2677241_-	SUKH-3 domain-containing protein	NA	NA	NA	NA
WP_012861951.1\|2679009_2679546_-	hypothetical protein	NA	NA	NA	NA
WP_115388852.1\|2679561_2679885_-	hypothetical protein	NA	NA	NA	NA
WP_012861953.1\|2679902_2680331_-	M15 family metallopeptidase	A9DET4	Yersinia_phage	3.9e-20	40.3
WP_169305405.1\|2680530_2680677_-	hypothetical protein	NA	NA	NA	NA
WP_012861955.1\|2680660_2680813_-	hypothetical protein	NA	NA	NA	NA
WP_012861956.1\|2680821_2681910_-\|tail	phage tail protein	A0A0C5AEQ0	Bacteriophage	1.9e-23	40.0
WP_012861957.1\|2681923_2682565_-\|tail	phage tail protein	A0A0C5AJ63	Bacteriophage	6.5e-27	40.2
WP_169305406.1\|2682561_2682870_-	hypothetical protein	A0A067ZJB4	Vibrio_phage	4.3e-13	43.4
WP_012861959.1\|2682902_2683640_-\|portal	phage portal protein	A0A067ZJA4	Vibrio_phage	6.7e-44	39.1
WP_012861960.1\|2683654_2683879_-	hypothetical protein	A0A067ZJ01	Vibrio_phage	5.4e-13	48.6
WP_012861961.1\|2683878_2685693_-\|terminase	phage terminase large subunit family protein	A0A2K9V3X4	Faecalibacterium_phage	1.8e-146	46.4

DBSCAN-SWA_8

3036569 : 3042356

Bacillus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012862307.1\|3036569_3037250_+	Rha family transcriptional regulator	A0A2I6PG08	Plesiomonas_phage	5.3e-27	32.9
WP_012860284.1\|3037644_3037854_-	helix-turn-helix transcriptional regulator	Q331Y7	Clostridium_botulinum_C_phage	1.5e-12	50.7
WP_115388830.1\|3038011_3038638_+	phage antirepressor N-terminal domain-containing protein	A5VW58	Enterobacteria_phage	1.2e-09	28.3
WP_012860282.1\|3038753_3039368_+	ERF family protein	A0A090D840	Clostridium_phage	2.5e-36	45.5
WP_012860281.1\|3039367_3039745_+	single-stranded DNA-binding protein	A0A218KCM4	Bacillus_phage	7.7e-20	42.6
WP_012860280.1\|3039792_3040068_+	hypothetical protein	NA	NA	NA	NA
WP_012860279.1\|3040076_3040913_+	hypothetical protein	H7BVI6	unidentified_phage	1.1e-26	50.7
WP_012860278.1\|3040950_3041220_+	hypothetical protein	NA	NA	NA	NA
WP_012860277.1\|3041228_3041384_+	hypothetical protein	NA	NA	NA	NA
WP_012860276.1\|3041373_3041718_+	hypothetical protein	A8ASN9	Listeria_phage	1.2e-16	46.0
WP_012860275.1\|3041714_3041975_+	hypothetical protein	NA	NA	NA	NA
WP_012860274.1\|3041975_3042356_+	hypothetical protein	R4JMS5	Bacillus_phage	4.0e-08	30.0

DBSCAN-SWA_9

4080616 : 4158462

Staphylococcus_phage(20.0%)

capsid,plate,terminase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012863258.1\|4080616_4083397_+\|protease	autotransporter serine protease	NA	NA	NA	NA
WP_012863259.1\|4083487_4085968_-	autotransporter outer membrane beta-barrel domain-containing protein	NA	NA	NA	NA
WP_012863260.1\|4086200_4087064_+	AraC family transcriptional regulator	D0R0F8	Streptococcus_phage	1.8e-24	27.2
WP_012863261.1\|4087078_4087525_+	GyrI-like domain-containing protein	NA	NA	NA	NA
WP_012863262.1\|4087568_4088546_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.2e-21	30.0
WP_012863263.1\|4088517_4089276_+	ABC transporter permease	NA	NA	NA	NA
WP_012863264.1\|4089374_4090943_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012863265.1\|4091096_4092689_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012863266.1\|4092718_4094329_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012863267.1\|4094351_4095284_-	ATP-binding cassette domain-containing protein	M1IB70	Acanthocystis_turfacea_Chlorella_virus	1.8e-06	25.1
WP_012863268.1\|4095283_4096324_-	ABC transporter ATP-binding protein	A0A2H4UU96	Bodo_saltans_virus	1.0e-05	25.1
WP_012863269.1\|4096335_4097265_-	ABC transporter permease	NA	NA	NA	NA
WP_012863270.1\|4097264_4098242_-	ABC transporter permease	NA	NA	NA	NA
WP_012863271.1\|4099138_4105555_-	autotransporter domain-containing protein	NA	NA	NA	NA
WP_012863273.1\|4106149_4106536_-	hypothetical protein	NA	NA	NA	NA
WP_012863274.1\|4106755_4107379_+	hypothetical protein	NA	NA	NA	NA
WP_012863275.1\|4107418_4108249_-	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_012863276.1\|4108251_4109007_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_012863277.1\|4109025_4109511_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_012863278.1\|4109529_4109940_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_012863279.1\|4110013_4110766_-	oxo-acid lyase	NA	NA	NA	NA
WP_012860144.1\|4110902_4112000_-	DgaE family pyridoxal phosphate-dependent ammonia lyase	NA	NA	NA	NA
WP_012863280.1\|4112235_4113483_+	replication initiation protein	NA	NA	NA	NA
WP_012863281.1\|4113503_4113869_-	DUF1634 domain-containing protein	NA	NA	NA	NA
WP_012863282.1\|4113870_4114704_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_012863283.1\|4114985_4116248_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_012863284.1\|4116269_4117580_+	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_012863285.1\|4117665_4118388_+	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_012863286.1\|4118466_4119201_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_041310132.1\|4119365_4119926_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_012863288.1\|4120086_4121793_-	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	9.5e-17	30.9
WP_012863289.1\|4121816_4123025_-	FprA family A-type flavoprotein	NA	NA	NA	NA
WP_012863290.1\|4123165_4123846_-	ankyrin repeat domain-containing protein	A0A068EL37	Pigeonpox_virus	2.7e-07	31.1
WP_012863291.1\|4124043_4124529_-	hypothetical protein	NA	NA	NA	NA
WP_012863292.1\|4124855_4125551_-	hypothetical protein	NA	NA	NA	NA
WP_012863294.1\|4133951_4134134_-	hypothetical protein	NA	NA	NA	NA
WP_012863295.1\|4134151_4134457_-	hypothetical protein	NA	NA	NA	NA
WP_012863296.1\|4134532_4134949_-\|holin	phage holin family protein	M9Q253	Clostridium_phage	2.8e-15	37.6
WP_012863297.1\|4134962_4135466_-	hypothetical protein	NA	NA	NA	NA
WP_012863298.1\|4135543_4136290_-	N-acetylmuramoyl-L-alanine amidase	NA	NA	NA	NA
WP_012863299.1\|4136300_4137509_-	hypothetical protein	NA	NA	NA	NA
WP_012863300.1\|4137519_4137957_-	hypothetical protein	A0A075BS47	Microcystis_phage	1.2e-13	43.8
WP_012863301.1\|4137971_4138433_-\|plate	BppU family phage baseplate upper protein	NA	NA	NA	NA
WP_012860737.1\|4138445_4139735_-	hypothetical protein	NA	NA	NA	NA
WP_012860736.1\|4139735_4140332_-	hypothetical protein	NA	NA	NA	NA
WP_012860735.1\|4140334_4140946_-	hypothetical protein	NA	NA	NA	NA
WP_012860734.1\|4140956_4141250_-	hypothetical protein	NA	NA	NA	NA
WP_012863302.1\|4141233_4143522_-	hypothetical protein	NA	NA	NA	NA
WP_012863303.1\|4143524_4149302_-	hypothetical protein	A0A1B3AYR8	Gordonia_phage	3.7e-20	28.0
WP_012863304.1\|4149314_4149551_-	hypothetical protein	NA	NA	NA	NA
WP_012863305.1\|4149550_4150141_-	hypothetical protein	NA	NA	NA	NA
WP_012863306.1\|4150153_4151092_-	hypothetical protein	NA	NA	NA	NA
WP_012863307.1\|4151095_4151491_-	hypothetical protein	NA	NA	NA	NA
WP_012863308.1\|4151491_4151827_-	hypothetical protein	NA	NA	NA	NA
WP_012863309.1\|4151838_4152837_-\|capsid	major capsid protein	NA	NA	NA	NA
WP_012863310.1\|4152849_4153227_-	hypothetical protein	NA	NA	NA	NA
WP_115388815.1\|4153228_4154104_-	hypothetical protein	NA	NA	NA	NA
WP_012863312.1\|4154117_4154687_-	phage virion morphogenesis protein	NA	NA	NA	NA
WP_012863313.1\|4154676_4156863_-\|capsid	minor capsid protein	NA	NA	NA	NA
WP_041310142.1\|4158006_4158462_-\|terminase	terminase	A0A1W6JNP5	Staphylococcus_phage	1.5e-41	59.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_013517

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection