CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_014103	Bacillus megaterium DSM 319, complete sequence	10 crisprs	DinG,csa3,cas3,WYL,DEDDh	1	3	3	0

1. NC_014103

CRISPR-Cas detection and classification

Crispr_ID: NC_014103_1

• CRISPR_ID: NC_014103_1
• CRISPR_location: 331985-332070
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DinG

Consensus repeat of NC_014103_1

Consensus_repeat	Method
AATCAAGGCGGAGAGAGGCCAACGGA	CRISPRCasFinder

spacers of NC_014103_1

>1.1|332011|34|NC_014103|CRISPRCasFinder
CCCTGGGGAAGGTGACGGAACTCAGCCAGATCCG

CRISPR arrays and Neighbor proteins around NC_014103_1

CRISPR arrays

The CRISPR arrays of NC_014103_1

>merge|NC_014103|1|331985-332070|CRISPRCasFinder
AATCAAGGCGGAGAGAGGCCAACGGACCCTGGGGAAGGTGACGGAACTCAGCCAGATCCGAATCAAGGTGGAGAGAGGCCAACGGA

>NC_014103|1|1|331985-332070|CRISPRCasFinder
AATCAAGGCGGAGAGAGGCCAACGGA	CCCTGGGGAAGGTGACGGAACTCAGCCAGATCCG
AATCAAGGTGGAGAGAGGCCAACGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013055105.1|324384_324678_+|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|274862
NC_014103.1|WP_013055106.1|324771_325011_+|hypothetical-protein	unknown	unknown	gnl|CDD|227704
NC_014103.1|WP_013081511.1|343531_344464_+|D-2-hydroxyacid-dehydrogenase	unknown	unknown	gnl|CDD|240625
NC_014103.1|WP_013081512.1|344563_345649_+|nitric-oxide-synthase-oxygenase	unknown	unknown	gnl|CDD|376957
NC_014103.1|WP_013081509.1|340623_341520_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013081500.1|325025_326330_+|type-VII-secretion-protein-EssB	unknown	unknown	gnl|CDD|188441
NC_014103.1|WP_013081498.1|321076_322282_+|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl|CDD|223587
NC_014103.1|WP_013081507.1|338238_338754_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|237597
NC_014103.1|WP_013081496.1|318570_319323_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NC_014103.1|WP_013081504.1|334525_335002_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013081508.1|339122_340460_+|transcriptional-regulator	unknown	unknown	gnl|CDD|379358
NC_014103.1|WP_013081506.1|336551_338189_+|family-14-glycosylhydrolase	unknown	unknown	gnl|CDD|366599
NC_014103.1|WP_013081510.1|341714_343271_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NC_014103.1|WP_013055102.1|322532_322850_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013081505.1|335290_336445_+|endonuclease	unknown	unknown	gnl|CDD|225231
NC_014103.1|WP_013081501.1|326342_330821_+|type-VII-secretion-protein-EssC	unknown	unknown	gnl|CDD|274860
NC_014103.1|WP_013081503.1|333977_334475_+|type-VII-secretion-protein-EssA	unknown	unknown	gnl|CDD|375148
NC_014103.1|WP_034654747.1|319400_320711_+|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|236901
NC_014103.1|WP_013081499.1|322959_323559_+|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|377587
NC_014103.1|WP_013055104.1|323620_324013_+|SseB-family-protein	unknown	unknown	gnl|CDD|377787

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_014103.1|WP_013081498.1|321076_322282_+|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	2.8e-12	40.4	1.9

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013055105.1|324384_324678_+|WXG100-family-type-VII-secretion-target	gnl|CDD|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	1.56462e-22
NC_014103.1|WP_013055106.1|324771_325011_+|hypothetical-protein	gnl|CDD|227704	COG5417, COG5417, Uncharacterized small protein [Function unknown].	2.88289e-28
NC_014103.1|WP_013081511.1|343531_344464_+|D-2-hydroxyacid-dehydrogenase	gnl|CDD|240625	cd05300, 2-Hacid_dh_1, Putative D-isomer specific 2-hydroxyacid dehydrogenase. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomains but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric. Formate dehydrogenase (FDH) catalyzes the NAD+-dependent oxidation of formate ion to carbon dioxide with the concomitant reduction of NAD+ to NADH. FDHs of this family contain no metal ions or prosthetic groups. Catalysis occurs though direct transfer of the hydride ion to NAD+ without the stages of acid-base catalysis typically found in related dehydrogenases. FDHs are found in all methylotrophic microorganisms in energy production and in the stress responses of plants.	3.36413e-116
NC_014103.1|WP_013081512.1|344563_345649_+|nitric-oxide-synthase-oxygenase	gnl|CDD|376957	pfam02898, NO_synthase, Nitric oxide synthase, oxygenase domain.	0
NC_014103.1|WP_013081500.1|325025_326330_+|type-VII-secretion-protein-EssB	gnl|CDD|188441	TIGR03926, T7_EssB, type VII secretion protein EssB. Members of this family are associated with type VII secretion of WXG100 family targets in the Firmicutes, but not in the Actinobacteria. This protein is designated YukC in Bacillus subtilis and EssB is Staphylococcus aureus. [Protein fate, Protein and peptide secretion and trafficking].	3.66531e-115
NC_014103.1|WP_013081498.1|321076_322282_+|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	5.53152e-114
NC_014103.1|WP_013081507.1|338238_338754_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|237597	PRK14054, PRK14054, peptide-methionine (S)-S-oxide reductase.	1.54811e-90
NC_014103.1|WP_013081496.1|318570_319323_+|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	1.73909e-14
NC_014103.1|WP_013081508.1|339122_340460_+|transcriptional-regulator	gnl|CDD|379358	pfam13749, HATPase_c_4, Putative ATP-dependent DNA helicase recG C-terminal. This domain may well interact selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	2.47041e-08
NC_014103.1|WP_013081506.1|336551_338189_+|family-14-glycosylhydrolase	gnl|CDD|366599	pfam01373, Glyco_hydro_14, Glycosyl hydrolase family 14. This family are beta amylases.	0
NC_014103.1|WP_013081510.1|341714_343271_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_014103.1|WP_013081505.1|335290_336445_+|endonuclease	gnl|CDD|225231	COG2356, EndA, Endonuclease I [DNA replication, recombination, and repair].	1.10228e-59
NC_014103.1|WP_013081501.1|326342_330821_+|type-VII-secretion-protein-EssC	gnl|CDD|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_014103.1|WP_013081503.1|333977_334475_+|type-VII-secretion-protein-EssA	gnl|CDD|375148	pfam17355, DUF5383, Family of unknown function (DUF5383). This is a family of unknown function found in Bacillales. Members of this family are predicted to contain one trans-membrane region.	2.88762e-39
NC_014103.1|WP_034654747.1|319400_320711_+|PAS-domain-S-box-protein	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.87674e-58
NC_014103.1|WP_013081499.1|322959_323559_+|WXG100-family-type-VII-secretion-target	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	0.000372258
NC_014103.1|WP_013055104.1|323620_324013_+|SseB-family-protein	gnl|CDD|377787	pfam07179, SseB, SseB protein N-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This entry contains the presumed N-terminal domain of SseB.	2.64916e-09

Protein sequences

>NC_014103.1|WP_013081501.1|326342_330821_+|type-VII-secretion-protein-EssC
MNMLWVVSGQTYQQLPVDFKTFRQATVGNAQHQTFTFSYPFEKGQMTLSSEKNGRLLISYGEKRIAELSVSESFVWREQGHALTFVLTDTAVKEAVYYIDYGSEVSFSTSDETADVYQQKEKCVVEPKEGFYLSKINGKWKVFYNQEPLYLNGHRLEENTNLQPGDLILWSSMTIQLIEKDLLKIQSCYDYASKLPTTAQPISEMKKKYPVYRRTPRMIYDLPNDKVSLSFPSQDNDENNRSLWLTILPPLVMLLVMGTVSIIQPRGIFIIISVMMFTTTLIVSTVQYFKDKKQRKKRQERRRRIYTKYLENKREELQELVSVQRDVLSYHFPTFERMKYLTEQISDRIWERTVESSDFLQVRLGTGTVPGSYQISLNSGDMANREIDDLLEQSQHMEKIYREVKNAPVTAHLGLGSIGLVGKMKTVKNELHQLVGQLAFSHSYHDVRFVFIFDEEEYKEWEWMKWLPHFQLPHSFAKGFIYNEQTRDQLLSSIYEMLRERDLDEAKEEGVFLPHFVFIITNQQLIADHVILEYLEGYHPHLGFSAIFAAETKESLTEHVHTLVRYINESEGDILIQKQKAVNIPFQLDKHTLDYNERFARMLRTLDHQVGMTNSIPNSVSFLELFKAREIGELDIVQRWQSNESAKSLAVPIGLKGKEDIVELNLHEKAHGPHGLLAGTTGSGKSEFLQTYILSLAVNFHPHEVAFLLIDYKGGGMAQPFKNMPHLLGTITNIEGSKNFSTRALASIKSELKRRQRLFDRYEVNHINDYTDLYKQSMAEEPLPHLFLISDEFAELKSEEPEFIRELVSAARIGRSLGVHLILATQKPGGVIDDQIWSNARFKVALKVQDAADSKEILKNADAASITVTGRGYLQVGNNEVYELFQSAWSGAPYMEDTYGAEDEVAIVTDLGLIPLSDVSTQQTSSKQAEAEIDVVVQKIEKTQQELAIKKLNSPWLPPLKERLLRSEYTEKRDGVFPIGLIDEPEKQSQTVYNYQLMDDGNIGIFGSSGYGKSFTVMMLLLNLAERKSPEQLHYYIFDFGNGTLLPLRQLPHTADYFLMDQMRKIEKFMTIIKQEIARRKQLFQQREVSNIKMYNALSSEELPLIFITIDNFDLVKEEMQDLEMQFTQLVRDGQSLGIYMIFTATRVNSIRQSLMNNLKTKVVHYLMDHSEAYSILGRTPYALESIPGRAIIKTDQPYFAQLFLPAEGKDDFEIFDAVKLHIQRLKNQYADAIVPEPVPMLSSKLVLVEFMTDRRVIREKGVIPLGLDEEFVRPVHMNFTKNKHCIVMGQTQKGKTNVVKVILQTALEQGVKQIGLFDSVDRGLSSYAAEEQVVYMETKEQIIDWLDLTEERLQRREIKYLEAVQEGTVHSLSFAPIMLVVDGFVRFQQNLDSVLQDRITKLMKNYSHLGFNLIVAGNNNEFSKGFDALTTEVKQISQAVLLMKKTEQSLFTLPYDRKEADINPGFGYYIKSGKETRIQIPLCVSERKILT
>NC_014103.1|WP_013081500.1|325025_326330_+|type-VII-secretion-protein-EssB
MSEKKPTYLEEQLEAVMTRHNNEYTFVFQKEKIRLNRSVEIEMLKDVNTAFQKEIMMSDDELKITIKPTSEFQPFTALRGKEEQQKWLFADQLIKQVKQHSFSRLHLLICPENIIFDKSLSPAFLHYGVKESLPPYESNGEQSFQELKATIAAAVDSSHTFEQYFKLYETLQLKEDAKKIMHISNEEELSQFVQHKLTQIEKHQKTLVQLPQKRWTIFKFSSVGILVLLIPALIYTFYSYFFAQPKQEAFVESNEYFLEKNYSKVVDILEDYDIESMPEIVQYEIATSYLVNEKLGEEQKANALKAITLQSDPQYFAYWFYIGRGDNKKALEVSRLLEERSLIIYALMKYEGQLKTDNDLAADKKQEELDKVANELEEFKKENDQQEAEAAKQQEEKQAEEAQAAKQQEEEQKAAEAEKKKQEEQKKQQEDQSK
>NC_014103.1|WP_013055106.1|324771_325011_+|hypothetical-protein
MYIEVTVDLKHYTGDRFDLRLSNYHSLKKVVEIVWQAKKITQSPKDGAWIRVSNKNLIFSGNETMINCGITTGDCIEIL
>NC_014103.1|WP_013055105.1|324384_324678_+|WXG100-family-type-VII-secretion-target
MSGIIRVTPAELRDMAGRYTNESGQVQELVSRLDTMKNQLQDMWEGASSEAFAAQYEELKPSFVEMSNLLTKIAKQLDDSANVLEDTDNQIASQIRG
>NC_014103.1|WP_013055104.1|323620_324013_+|SseB-family-protein
MKYTFNLLEKSLIEAMKDNKKIAQFYKTLMNSNLWLVVSSEHGASDILIAEHYVQTMKSAAYRYLPVFSSKYPIEQMLKDEKTVCVSFKDMLPVLNEEIAILLNPDTPLSKLFIPEEIRMLKEDQNYFKQ
>NC_014103.1|WP_013081499.1|322959_323559_+|WXG100-family-type-VII-secretion-target
MEIKVNPEVLRTFAERIQHSHSQTADALQKLSWEATNLHFLSVADIDKVLDLQEELQHMIRKLDSLTENAHLLVKDTAEQMRKADGELEGSSGWTEFWSSVWSNGGTHSQDTWNDIKNLKEWNTYDNMHRTIEKPLGTLNVMWNSLSMSWEEKVVNGSTCSRTEFFTYGVIQMGLGILSQEMNPSNIMFSDSTEEVKRE
>NC_014103.1|WP_013055102.1|322532_322850_+|hypothetical-protein
MDAIDDLFDDIERRRKSKEYSRDADQLESYLHEVQRIMEFLEEGIYLFQNSHQQYASDWSGRSKSSYEDIYNDITQSTFHLYDVRDELFQTLRLEISRLRELASA
>NC_014103.1|WP_013081498.1|321076_322282_+|DEAD/DEAH-box-helicase
MSQFIETLQPFLQEAWKKAGFNEPTAIQTKAISEILANKDVIGESPTGTGKTLAYLLPVLHRIQPGPSHIQAVILASSHELVMQIHGEIQTWSQGSGISSAAFIGGANMKRQLEKLKKRPNIIVGTPGRLNELIKMKKLKMHEVKTIVIDEADQLFVPEHVQTVQQIVKMALSDRQILVFSATVSERTKSLAKDMMNHPLEIEVGRDELPASKVEHVYIKSEARDKVDVLRKLVRQEQMKALAFFKGIDTLIEFEEKLTFKRVEAGSLHSETKKEDRATTIKGFRKGDFPVLLATDVAARGLDIKGLTHVIHIDVPQDADQYVHRSGRTGRSGAEGTVISLVTEREERNLKQIARELQLSLVKKELYMGEIVDEGTKEQSRTAKKPSKKPFNKKKKQKGRM
>NC_014103.1|WP_034654747.1|319400_320711_+|PAS-domain-S-box-protein
MVKHARKVALRISIIYIIIGAVWILISDNISRTLAQGRFEVYIFFQQYKGWLFILATGIILYGLVYRRAYKLVESQQELVVKEHELQTSNQHYQSLFKHNPDGVFEISKTGEVLLANPEGEAIVGYSSEELQKMKPSALIAAEEFDMCKEYFKEVLNGKGAKFEMNVINRKRERRLLRCSLLPIIVHKQVVGVFMIARDITTYRQDEELMITSEKMSVIGQMAGAVAHEIRNPLTSLKGFVQVMQASKETNDTYLDIMMSEIDRINLISSEMLILGKKQHVSFEKTNLCEILKQVVTLMEAQANLNNVSILLKETAKRPIYVSADSNQLKQVFINVIKNGVEAIMEKGHITITVEEKDTRALIHFEDNGIGMSQERIEQVGTPFYSTKEAGTGLGLAVCYKIMERHQGTMHFKSGKGKGTTVIIDMPIIERNSRLS
>NC_014103.1|WP_013081496.1|318570_319323_+|STAS-domain-containing-protein
MSTIKYAPLPVFIMDEEMNILAQSDEAAALFGEVQHFLEIVDEDSQIKARKRLGQKKKIKTELVMHSRKAKMSLYTVNCKWEQGKAHVICVEEDSQIRILSEKIQQHTARLSETDLELLLQKERLEKAMNRVIELSGPFIHLSNNMVLIPLFGDLFEEVIMKNEHRLLRQTDEETVDRVIIDFNGIGQIDERGVAALEHLIWEFQLMGVQIYLTGVTPDHSQWLHQYHFQANVKSISNLGQAIHQFFTTA
>NC_014103.1|WP_013081503.1|333977_334475_+|type-VII-secretion-protein-EssA
MMKPIVLNKKIGSIVLIFSLLYFPIAAAAEADDGNVEEIKPNVYKDDPINLDPESLLENKKEVGNIPEDIKDLTFEKEEDVEKESLKESIFANASAGDNTISAKAKEYNLFSSKNTSYKKDRTEQTASEKSSDLQWFYLLLIGVGVVVLFAVLIPRISPQPSVKK
>NC_014103.1|WP_013081504.1|334525_335002_-|hypothetical-protein
MLSFDEKLAIISSFPELHRKDVSLGRVNFHYEESVYDKTVVVHHLHPNGNGFVYGGFLKGYETNDKGLVNIRDYTEEELRSIIEASIESLSTLPDTAREEAIVGNGNEQRWNGPDNATLLLVHEDDLWNVYSGLNLEAAFLSYEEAEDYLFEEGFRRL
>NC_014103.1|WP_013081505.1|335290_336445_+|endonuclease
MKLYALCKKTWAISLLVFVLLVSLTPVSQAAAFLSVAQALEHQNNSVQTVKGYVVGQPTGTSTVITSNYPNDYALALAASSNETNTDKMVYVQIPSNLRSTFGLQSHSELRGKSLTVTGTLTPYFSHPGIKSVTSISTETGGTDPAPDPTEPTVPVEDYYRTVAEKTGNSLKTELHNIIDHHTELSYSAVWEALKKTDEDPANANNVILLYTGRSQAKSTNGGGVDDWNREHVWAKSHGDFGTAMGPGTDLHHLRPTDVSVNSTRGNLDFDNGGTEHSEALGNYFDSDSWEPRDEVKGDVARMLFYMAVRYEGDVSDEPDLELNNTVNNGTAPYHGKLSVLLQWNAQDPVDDRERRRNDIIYSDYQHNRNPFIDHPEWVNEIWN
>NC_014103.1|WP_013081506.1|336551_338189_+|family-14-glycosylhydrolase
MKQLCKKGLAFVLMFIFVNAFILSPINGAAAVDGKSMNPGYKTYLMAPLKKVTDYTTWEAFENDLRKAKQNGFYAVTVDFWWGDMEKNGDQQFDFSYAQRFAQAARNAGIKIVPIISTHQCGGNVGDDCNVPLPSWVWNLKSDDSLYFKSETGTTNKETLSPLATDVISKQYGELYTAFAQALAPYKDVIAKIYLSGGPAGEIRYPSYTAADGTGYPSRGKFQVYTNFAKSKFQSYALTKYGSLAGINQAWGTNLTSASQILPPSDGYQFLKDGYSTAYGKDFLAWYQGALEDHTKRIGQLAHQAFDSTFNVPIGAKVAGIHWQYNNPTIPHAAEKPAGYNDYNALLDAFKTAKLDITFTCLEMTDSGNYPEYSMPKKLVRQVAGIANAKGVVLNGENALTIGSEDQYTKAAEMAFNYNFAGFTLLRFYDVINNDTLMGQFKNTLGVTPLAQTVVVKNAPTALGETVYIVGDRAELGQWDTSIYPIKLTYNSSTADWRGTVHFPASQNVQFKAIVKRADGSLKAWQPSQQYWSVPSTTTTYTDNW
>NC_014103.1|WP_013081507.1|338238_338754_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MEKATFAGGCFWCMVTPFEELEGIHGIVSGYMGGTVDNPTYGQVKSGTSGYYEVVQITFDPEVFPYKRLLDLYWPQIDPTDDGGQFQDRGSQYRTAIFYHNDSQKQAAEETKLEVAESGRFKKPIVTSILPASTFYEAEEYHQDFHKKNPKHYKEDRAKSGRDEFIETNWK
>NC_014103.1|WP_013081508.1|339122_340460_+|transcriptional-regulator
MLQDNLILEHYGLNELNFDTIKSYRDRFAEVKPAHPWNALETKEFLYKVGAWGKVRDTHKEGVTLAGLLLFSEERIITEVLPQYFLEYRESKGNEEWTERFTSQDGTWSGNIFDFYFHIHEIVRNSEPQPSIASSLTEVLINMLIHADYNGEGGVILEKQPSHYVFSNPGLLLVPTDSVFSNTVSQLRNPNIVKLFSLLGLCERSGSGLKKVKQNWSLHHYKTPAIDQDVSMHRTVVTLSLSTQERQVSSSEKDTYNMSITDSGNNFKDVEKYQNTPENNVEIDSYNKNNYSYNKGLIEEFKSYNKDVNSFNKEDNYYNKEINLYNKDVNSYNNNHNSYNNGQEEDSSNLLNVENIDTRLWDIAAMAREKKRLSPNQMEHIILELCKEKPLMLKEFAYLLERTPDGVRNNYLTKLLRKGQLQLKYPNQPNHPKQAYLFNKKDIEK
>NC_014103.1|WP_013081509.1|340623_341520_+|hypothetical-protein
MKSKCVLIFLVVVWLFNMGKGIGCGSKVNAEINIPLSTWVWDTKKWMLNQEAILEKLQEKKVTNVYLQIDTHLSPSVYQHFIQQAQAQGISVYALDGAPYWIGPSGIEEQEAFFNWITAYQAQADEPQQFSGVHLDVEPYLYKSWENNRAKSILQYQYVISQAAVQSHELHLPLAVDIPFWFDEVPFKNSNGSGSLGRWIIQYAGEVTIMAYRNYADKENGIAEITENERKWGRVLSTPIEIGIETMASDEGEYISFSAKGEEKMMQELGMLLTKCQAENPPSSIAVHYFDSWLQMKP
>NC_014103.1|WP_013081510.1|341714_343271_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSVLNVKNLSHGFGDRAIFNDVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLEPDAGKVEWSKKVRVGYLDQHIALERGLSIRDVLKSAFQYLFDLEAQMNGLYEKMADVSPEELEKLLEEVGTLQDLLTNNDFYVIDAKVEEIARGLGLEDIGLDRDVQDLSGGQRTKVLLAKLLLEKPEILLLDEPTNYLDEQHIEWLRRYLQEYENAFILISHDLPFLNSVINLIYHMENQELNRYVGDYDDFMKVYEMKKQQLEAAYKKQQQEMADLKDFVARNKARVSTRNMAMSRQKKLDKMEVIELAQERPKPEFNFKGARTSSKLIFETSDLVIGYGEPLSKPLNLKMERGQKIALVGANGIGKTTLLKSILGEIKPISGSVEKGDYQHIGYFEQEIKTANYNTCIEEVWNEFSHFTQYEIRAALAKCGLTTKHIESKVEVLSGGEKAKVRLCKLINNETNILVLDEPTNHLDVDAKDELKRALKEYKGSILIICHEPEFYQDVVTDVWNCESWTTKLF
>NC_014103.1|WP_013081511.1|343531_344464_+|D-2-hydroxyacid-dehydrogenase
MNIHTILVAGRMHKELEETIKQKQLSQTFRFMEEQDVTIEDLNWADALLSFGPTNCFEDHSFKWIHSLGAGVDQFLESGNWKKSVMLTRTICSFGQRISEYCLSYMLAELQHHAQFQHQQKQKQWKVVEPKQLSTQTVIIYGTGEIGGRLAAVLKSFGVRVMGVSKSGNEKPSFDQVVSISKEKELLKEADWIISTMPLTHETKSYFDSKWMNVVESAYFINVGRGATVDENALVEAIEQKRIRKAYIDVFEHEPLTKESSWWDHSNIIITPHISAVTTPEEAVECFVETLQKVEQGGLPSNLVNIERGY
>NC_014103.1|WP_013081512.1|344563_345649_+|nitric-oxide-synthase-oxygenase
MKQEELFEQARVFIETCYAELEKSEADKNKRLKEIHQQIMSLGHYDHTFEELEHGARMAWRNSNKCIGRLFWHSLNVFDKRDANTVEEIRDALFHHIEYATNDGKIRPTITVFKPKMKAKEPVRIWNHQLIRYAGYETEDGTIGDPDSVAFTEVCRNLGWEGEKTHFDVLPLVLQVNEGSPRCFDIPKHLVKEVAITHPELPEFEDLQLKWYAVPMISDMKLEIGGIDYVAAPFNGWYMGTEIGARNLADTYRYNQLPKIASMMELNMDYNATLWKDKALVELNVAVLSSFKREGVSIVDHHTAAQQFHLFEEREQKNGREVTGNWTWLIPPVSPATTHIFHKPYKNKVLSPNYFYQDAAY

Crispr_ID: NC_014103_2

• CRISPR_ID: NC_014103_2
• CRISPR_location: 385913-386011
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014103_2

Consensus_repeat	Method
GTGAAACAACAAAATGCTCAAGCA	CRISPRCasFinder

spacers of NC_014103_2

>2.1|385937|51|NC_014103|CRISPRCasFinder
TCTAAAAACAATTTCGGTACTGAATTTGGTAGCGAAACAAATGTACAAGAA

CRISPR arrays and Neighbor proteins around NC_014103_2

CRISPR arrays

The CRISPR arrays of NC_014103_2

>merge|NC_014103|2|385913-386011|CRISPRCasFinder
GTGAAACAACAAAATGCTCAAGCATCTAAAAACAATTTCGGTACTGAATTTGGTAGCGAAACAAATGTACAAGAAGTGAAACAACAAAATGCTCAAGCA

>NC_014103|2|2|385913-386011|CRISPRCasFinder
GTGAAACAACAAAATGCTCAAGCA	TCTAAAAACAATTTCGGTACTGAATTTGGTAGCGAAACAAATGTACAAGAA
GTGAAACAACAAAATGCTCAAGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_026106492.1|382328_383309_-|metal-dependent-hydrolase	unknown	unknown	gnl|CDD|224899
NC_014103.1|WP_013081550.1|389296_390385_-|aromatic-acid-exporter-family-protein	unknown	unknown	gnl|CDD|226614
NC_014103.1|WP_013055167.1|392435_393449_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213234
NC_014103.1|WP_013081552.1|393441_394233_+|ABC-2-family-transporter-protein	unknown	unknown	gnl|CDD|226953
NC_014103.1|WP_013081545.1|384676_384901_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013081549.1|387509_389261_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_014103.1|WP_013055156.1|381995_382265_+|YfhJ-family-protein	unknown	unknown	gnl|CDD|379438
NC_014103.1|WP_013055171.1|395583_396054_+|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl|CDD|224146
NC_014103.1|WP_013081548.1|386347_386608_+|hypothetical-protein	unknown	unknown	gnl|CDD|372951
NC_014103.1|WP_013055155.1|381704_381860_-|small,-acid-soluble-spore-protein-K	unknown	unknown	gnl|CDD|285399
NC_014103.1|WP_013055154.1|381305_381620_+|YfhH-family-protein	unknown	unknown	gnl|CDD|378063
NC_014103.1|WP_193345438.1|385014_385767_+|enoyl-[acyl-carrier-protein]-reductase-FabL	unknown	unknown	gnl|CDD|236145
NC_014103.1|WP_013081540.1|378478_379381_-|TIGR01777-family-protein	unknown	unknown	gnl|CDD|187553
NC_014103.1|WP_013081554.1|395121_395514_+|two-pore-domain-potassium-channel-family-protein	unknown	unknown	unknown
NC_014103.1|WP_034655325.1|394242_395028_+|ABC-2-family-transporter-protein	unknown	unknown	gnl|CDD|226218
NC_014103.1|WP_013081541.1|379478_380288_+|recombination-regulator-RecX	unknown	unknown	gnl|CDD|237619
NC_014103.1|WP_013055163.1|386803_387340_+|DUF402-domain-containing-protein	unknown	unknown	gnl|CDD|184219
NC_014103.1|WP_013081551.1|390934_392233_-|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl|CDD|183493
NC_014103.1|WP_013081542.1|380569_381223_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187643
NC_014103.1|WP_013081544.1|383548_384643_+|A/G-specific-adenine-glycosylase	unknown	unknown	gnl|CDD|224115

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_026106492.1|382328_383309_-|metal-dependent-hydrolase	gnl|CDD|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	3.50396e-35
NC_014103.1|WP_013081550.1|389296_390385_-|aromatic-acid-exporter-family-protein	gnl|CDD|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	3.54796e-67
NC_014103.1|WP_013055167.1|392435_393449_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213234	cd03267, ABC_NatA_like, ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.	1.65462e-121
NC_014103.1|WP_013081552.1|393441_394233_+|ABC-2-family-transporter-protein	gnl|CDD|226953	COG4587, COG4587, ABC-type uncharacterized transport system, permease component [General function prediction only].	2.41995e-29
NC_014103.1|WP_013081549.1|387509_389261_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_014103.1|WP_013055156.1|381995_382265_+|YfhJ-family-protein	gnl|CDD|379438	pfam14043, WVELL, WVELL protein. This family includes the B. subtilis YfjH protein, which is functionally uncharacterized. This is not a homolog of E. coli YfjH, a synonym for IscX, which belongs to pfam04384. This family of proteins is found in bacteria. Proteins in this family are approximately 90 amino acids in length and contain a highly conserved WVELL motif.	7.28774e-43
NC_014103.1|WP_013055171.1|395583_396054_+|thioredoxin-dependent-thiol-peroxidase	gnl|CDD|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	5.31486e-80
NC_014103.1|WP_013055163.1|386803_387340_+|DUF402-domain-containing-protein	gnl|CDD|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	2.65481e-127
NC_014103.1|WP_013055155.1|381704_381860_-|small,-acid-soluble-spore-protein-K	gnl|CDD|285399	pfam08176, SspK, Small acid-soluble spore protein K family. This family consists of the small acid-soluble spore proteins (SASP) belonging to the K type (sspK). The sspK are unique to the spores of Bacillus subtilis and are expressed only in the forespore compartment of sporulating cells of this organism. The sspK gene is monocistronic and transcription is primarily by the RNA polymerase with the forespore-specific sigma factor, sigma-G. Mutation deleting sspK results in loss of SspK from the spore but had no discernible effect on sporulation, spore properties or spore germination.	2.82664e-17
NC_014103.1|WP_013055154.1|381305_381620_+|YfhH-family-protein	gnl|CDD|378063	pfam08838, DUF1811, Protein of unknown function (DUF1811). This is a bacterial family of uncharacterized proteins. Some of the proteins are annotated as being transcriptional regulators. The structure of one of the proteins in this family has revealed a beta-barrel like structure with helix-turn-helix like motif.	5.92623e-60
NC_014103.1|WP_193345438.1|385014_385767_+|enoyl-[acyl-carrier-protein]-reductase-FabL	gnl|CDD|236145	PRK08063, PRK08063, enoyl-[acyl-carrier-protein] reductase FabL.	2.76823e-172
NC_014103.1|WP_013081540.1|378478_379381_-|TIGR01777-family-protein	gnl|CDD|187553	cd05242, SDR_a8, atypical (a) SDRs, subgroup 8. This subgroup contains atypical SDRs of unknown function. Proteins in this subgroup have a glycine-rich NAD(P)-binding motif consensus that resembles that of the extended SDRs, (GXXGXXG or GGXGXXG), but lacks the characteristic active site residues of the SDRs. A Cys often replaces the usual Lys of the YXXXK active site motif, while the upstream Ser is generally present and Arg replaces the usual Asn. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.11849e-134
NC_014103.1|WP_034655325.1|394242_395028_+|ABC-2-family-transporter-protein	gnl|CDD|226218	COG3694, COG3694, ABC-type uncharacterized transport system, permease component [General function prediction only].	2.51572e-45
NC_014103.1|WP_013081541.1|379478_380288_+|recombination-regulator-RecX	gnl|CDD|237619	PRK14135, recX, recombination regulator RecX; Provisional.	8.10118e-120
NC_014103.1|WP_013081548.1|386347_386608_+|hypothetical-protein	gnl|CDD|372951	pfam14182, YgaB, YgaB-like protein. The YgaB-like protein family includes the B. subtilis YgaB protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 90 amino acids in length.	6.50685e-20
NC_014103.1|WP_013081551.1|390934_392233_-|glutamate-1-semialdehyde-2,1-aminomutase	gnl|CDD|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
NC_014103.1|WP_013081542.1|380569_381223_-|SDR-family-oxidoreductase	gnl|CDD|187643	cd08939, KDSR-like_SDR_c, 3-ketodihydrosphingosine reductase (KDSR) and related proteins, classical (c) SDR. These proteins include members identified as KDSR, ribitol type dehydrogenase, and others. The group shows strong conservation of the active site tetrad and glycine rich NAD-binding motif of the classical SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.36589e-54
NC_014103.1|WP_013081544.1|383548_384643_+|A/G-specific-adenine-glycosylase	gnl|CDD|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	2.49253e-150

Protein sequences

>NC_014103.1|WP_193345438.1|385014_385767_+|enoyl-[acyl-carrier-protein]-reductase-FabL
MMSQKVALVTGSSRGIGKEIALRLAKEGYDIVLNYARSKSAAQEVAEEIKALGREALVVKANVGKVEKIKEMFEQIDEAFGRLDVFVSNAASGVLRPIMELEETHWNWTMDINSKGYLFCAQEAAKRMEKVGGGKIVTISSLGSIRYLENYTTVGVSKAAVEALTRYLAVELAPKNIVVNAVSGGAVDTEALKHFPNRDELLDDARKHTPAGRMVEPRDMVDAVMFLVSDQANMICGQTLIIDGGRSLLM
>NC_014103.1|WP_013081545.1|384676_384901_-|hypothetical-protein
MYVGRDMTALSMISKSEWKDSELAFFHHSLQQMTPYLNAEGQSIHQQIIKEIEARGGLQRHEADYTHGTHISYD
>NC_014103.1|WP_013081544.1|383548_384643_+|A/G-specific-adenine-glycosylase
MKQSKDIVQNFDIRAFQDDLISWFEQEQRILPWRQDQDPYKVWVSEIMLQQTRVDTVIPYFNNFISKFPTIKDLAYANEDDVLKAWEGLGYYSRARNLQTAVREVHEQYGGEVPNTPAEISKLKGVGPYTTGAILSIAYGVPQPAVDGNVMRVLSRILSVWDDIAKPKTRKLFEDIVHEIISKDNPSYFNQGMMELGAIVCTPTSPSCLLCPVREHCRAFEEGVQNELPVKSKKKAPRALQLAAAVIREEDGNYLIHKRPSKGLLANLWEFPNIEVDLSIAPDHQQLQAFIQNEYGADIKINAPFTTIQHVFSHIVWNVTVYEAELVSDISALKNLKVVSEKDLEQYAFPVSHQKILKEYLLVK
>NC_014103.1|WP_026106492.1|382328_383309_-|metal-dependent-hydrolase
MDTGTHIAMGIALGGLATLDPTVSANTATLDAVMIGVMAGSLAPDLDTVLKLRNNAQYIRNHRGITHSIPAVILWPLLIVLILSLLLPGANLLHLWMWTFAGVIIHVFVDIFNAYGTQALRPFTNKWIALGVINTFDYVIFSAHVLAILIWFIGAEPGPTFITLYVLLAFYYGLRFYMRHQIAKKLRKQFPDVIKLNISPTLRFTHWHLAVTTEKYFHVGRAIGEEIFIYDTFDKVPIPESAVIEVAKKDENLSAFLSFSPIYRWELDEYNDHIEVRFIDLRYRSKDYYPFVAVVQLDYDLNIICSYTGWIFSEKKLRKKLDYLPH
>NC_014103.1|WP_013055156.1|381995_382265_+|YfhJ-family-protein
MNDIFERLTNQLLNKNSSLSYAQARTWVELFWEDFESSYAKAGYDYKGKEATEKVVTMYINSYGDKLHEIAVKNPKYQHLLNNDDYLKH
>NC_014103.1|WP_013055155.1|381704_381860_-|small,-acid-soluble-spore-protein-K
MRNKAKDFPNQHHTKFEGEPRAKAEYASKRANGTINTHPQERMHASNEREE
>NC_014103.1|WP_013055154.1|381305_381620_+|YfhH-family-protein
MSEKRYSDMTTYELQQEIGSLQEKARKAEQLGMVNEYAVLERKVTMARSYLLDPETFKAGEVYEIQGDPGSYFKIDYMNGVFAWGFRLGSPQNEEALPISMLKK
>NC_014103.1|WP_013081542.1|380569_381223_-|SDR-family-oxidoreductase
MKTVLITGGATGLGKELAKLYAKDYNVILAGRNQHKLKEAQHELGDNVYTMSVDITKYEELGKSVEKLLMQHSVDILINNAGIGHFGPLTDYTKQAIDEVIDTNVKGTIFLTQALMPHLLTRPEPKVMNIISTAGLRGKANESIYVASKFGVRGFTESLKVEYQDTSLHVIAAYMGGMNTPFWDHNNHIKDKSRLRSASEIAEIIYKQQNDSEDILF
>NC_014103.1|WP_013081541.1|379478_380288_+|recombination-regulator-RecX
MPVVTKITTQKNSGERYNVYLDYGKGEEFGFGVDENVLIKYDLKKGRELDEFELTEIQYADDEKKAYNLAITYLSYRMRSEKEVHDYLKKKEINSTIIQQVIQKLVSHRYLNDEEFAKAFVLTQMNTTSKGPSVIQRELKEKGISDSTITLSLCEYPEEQQIQTAVKLIEKLKGKYKKLSQVMMKQKMEQALAVKGYSFSIIQEAFQRTNTEKESDEAWEALQYQGMKAHRRFSKYEGWEYQQKMKQALYRKGFSIDQIQSFLDSIEEE
>NC_014103.1|WP_013081540.1|378478_379381_-|TIGR01777-family-protein
MKIVIAGGTGFVGKALTKHFLTQKHYVYILTRNADKAARDPKLKYVEWMQESSQPEEHVEGADVFINLAGVSLNSGRWTDERKKAIVESRLSSAQEILRIMAALPEKPFLYVNASAVGYYGTSTTETFTEASPSIGTDFLAETVKKWENEALKAMELNIRTVLTRFGVILGKDGGALPSTALPYKLFAGGTVGSGEQWMSWVHLQDVVKIIDYCIHTKQTEGPVNVTAPNPVQMEDFGKMIGKVLNRPHWMPVPSFGLQLLMGEMSMIILKGQRVLPEKLIQQNYIFTYTVLEDALRDLL
>NC_014103.1|WP_013081548.1|386347_386608_+|hypothetical-protein
MKKFDQLVTQQLETMDQLLFLQSEIERCQEIEGELIKLHEEAKLHSVQDEISEMKLKLKEIQLTFEAQTEDIIRTYKSEGACSTLA
>NC_014103.1|WP_013055163.1|386803_387340_+|DUF402-domain-containing-protein
MGIPVEGETIQIHSYKHNGHIHRVWDRTTVLKATNNLVIGGNDRTVVTESDGRTWVTREPAICYFHAQQWFNVIGMIREDGIYYYCNISSPFIYDDNEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHRKEMNYPEVIDRILHNHVEELKGWIRQRKGPFAPDFIDIWYERFLTYRHS
>NC_014103.1|WP_013081549.1|387509_389261_+|ABC-transporter-ATP-binding-protein
MGSIRRYMKFVQPYKWQIVGTVLIGIIKFAIPLLIPLLLKYVLDDIVNGHGMSSSEKVHKMVTIMGISFVIFLVLRPPIEYYRQYYAQWVSSKVLYDIRDQLFSHIQKLSLRYYANTRAGEVISRVINDVEQTKNFVITGLMNVWLDMMTIVIAIVIMFTMNVPLTLVSIILLPVYAFSVKYFYSRLRHLTRVRSQALAEVQGHLHERVQGISVIRSFAIEPHEQKQFDKQNSNFLQKAINHTNWNAKTFAVVNTITDLAPLIVITFAGYQVITESLSVGTMVAFVAYIDRLYNPLRRLVNSSTTLTQSVASMDRVFEFIDEEYDITDKKDAKECTELHGKVQFEHVSFAYEEEEKPVIHDINLDVEKGKSVAFVGMSGGGKSTLISLIPRFYDVTEGKILIDDIDIKTYKVRSLRDKIGIVLQDTVLFSDTVKNNILLGKPGATDEEVIAAAKAANAHDFIMNLPEGYDTKVGERGMKLSGGQKQRISISRVFLKNPAILIFDEATSALDLESEHYIQEALAELAKDRTTFIVAHRLSTITHVDEIVLLENGRVVERGSHEELIKKKGHYYQLFNVQQLDTI
>NC_014103.1|WP_013081550.1|389296_390385_-|aromatic-acid-exporter-family-protein
MKLGARILKTGIAITLSLLLGEFLSLPSPIFAAIAAVFAIQPSIYRSYLTILEQIQANVIGAASAVCFGLIFGTHPIIIGFTAVVVIAVNLKLRINNTIGLALVTVIAIMENPGDNFVEYALIRFGTVLLGVFSAFIVNLIFIPPKYETRLYYKIVSTTEEIIKWIRMNLYHASEHTLLKEDIEKMKDNVAKMNQIFDFYKEERTYSTKKRFVKSRKLVLFRQMITVTTRALTTLKLLHRVENDLQVMPQQFQDLIKSEVECLLMYHEQVLLKFIGKLRVQPTTTVPNEACVGKRALIDKFMQYKIYDNDEENKVIYHIFPLISVIIEYSEELEHLDKLIDTFQNYHKDANSFDINHQRQED
>NC_014103.1|WP_013081551.1|390934_392233_-|glutamate-1-semialdehyde-2,1-aminomutase
MQFTKSEQLHAEALEHIVGGVNSPSRSYKAVGGGAPVAMEKASGAYFWDVDGNKYIDYLAAYGPIITGHAHAHITKAITKAAETGVLYGTPTAHEVIFAKMLKEAMPALDKVRFVNSGTEAVMTTIRVARAYTGRDKIIKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVPKSIANEVITVPFNDIEPYKEALEKWGDQIAAVLVEPIVGNFGIVEPEPGFLEQVNELTHEAGALVIYDEVITAFRFMYGGAQDLLGVKPDLTAFGKIIGGGLPIGAYGGKKEIMEKVAPLGPAYQAGTMAGNPASILSGIACLEVLKQEGVYEQLDKLGAMLEEGILKHARTYNMPITINRLKGALTVYFTTETVKNYEQAENTDGELFARFFKLMLHQGVNLAPSKYEAWFLTTAHTEQDITDTLEAVEKAFKQLSEER
>NC_014103.1|WP_013055167.1|392435_393449_+|ATP-binding-cassette-domain-containing-protein
MKNAIEVNQLRKEFKAYSSRSGLKGAFRDLFTRNYRVMKAVNDISFTVKQGEMVGYIGENGAGKSTTIKMLTGILTPTSGDITVNGMNPHKEREKFAQTIGVVFGQRSQLWWDIAVQESFRLLKKVYKVSDEDYNAHMEHVIQTLDIGPLLDKPVRKLSLGQRMRCELAAALIHNPPLLFLDEPTIGLDVLVKLKIRQFLKEINEKYNTTILLTTHDLADIEALCERVVMLDEGSIIYDGSLQKLRSNWGDLKQVTFEFGTAPNKEQLKLLTQGMPVNWIEGDQKYLWTAQLQNKGDLMSQLIAKVVAKHEISDINIEEISTEEIIRNIYEEGVVNG
>NC_014103.1|WP_013081552.1|393441_394233_+|ABC-2-family-transporter-protein
MDKYIEMIRIRFLMMLAYRTNYYSGILIYAINIGAYYFLWSAIYGGKENIQGLSITQMTTYVAVSWMARAFYFNNIDREMATEIKDGKVAVELIKPYSYLGMKTMQGLGEGIFRLLFFSVPGMIIVAFLFPVQFSANAATWLYFGLSLIFSFIINTQINLLTGITTFFLFNNDGLIRAKRVVIDLFSGLLLPISFYPFWAQHIMSYFPFQAISYIPSMIFTNGFKGQEVINALITQAVWSGLLFIPIACLWNIAKKKMVIQGG
>NC_014103.1|WP_034655325.1|394242_395028_+|ABC-2-family-transporter-protein
MFYFSIFFQYIGQYMKTRLQYRTDMVVEIISDLLFQTVNLIFILVVFGHTQSLHGWSREEIIFIYGFFLVPFAIFSSFFNIWDFNERYIVKGEMDRILTRPIHSLFQVILERMELESLFGGVTGIAVMAYAASSLHLHFQWYDVFIFLLFILGGALVYAGIFIALASIGFWSDARTSIMPTIYNIGNYGRYPVDIYNNVIRYVLTWILPFAFVGVYPAAYFLGRSEWYGYAFLTPVMGIVFFVISIFLWNTGVKKYRGAGN
>NC_014103.1|WP_013081554.1|395121_395514_+|two-pore-domain-potassium-channel-family-protein
MVIFLILVIIVFVIGSMKFLFEKELGEFHFFSIGHFFVLFYSYITVLLGFSLIYTVCEMGSIPVLSGGFEHEGHYFYTLFNSMYFSAATLFSVGYGDMYPVGIGKLFATFEAFIGYIMPAIFVMRTVTRT
>NC_014103.1|WP_013055171.1|395583_396054_+|thioredoxin-dependent-thiol-peroxidase
MTAVVGEKAPDFVLMSTNGEQVSLASMKGKNVVLYFYPKDMTPGCTTEACDFRDQHENFEELDAVILGVSPDPIDKHHKFIDKHGLPFLLLADEDHSVAEEYGVWTLKKNFGKEYMGIERSTFIINKEGMLVKEYRKVRVKGHVEEALSFIKEKMA

Crispr_ID: NC_014103_3

• CRISPR_ID: NC_014103_3
• CRISPR_location: 1178258-1178467
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_014103_3

Consensus_repeat	Method
AGTAGAACGGCGAGTAGA	CRT

spacers of NC_014103_3

>3.1|1178276|30|NC_014103|CRT
GCGGCGAGTAGAACGGCGAGTAGAGCGATA
>3.2|1178324|30|NC_014103|CRT
ACGGCGAGTAGAGCGGCGAGTAGAGCGATA
>3.3|1178372|18|NC_014103|CRT
GCGGCGAGTAGAGCGATA
>3.4|1178408|42|NC_014103|CRT
GCGGCGAGTAGAGCGATAAGTAGAACGACGGCTAGAGCGACG

CRISPR arrays and Neighbor proteins around NC_014103_3

CRISPR arrays

The CRISPR arrays of NC_014103_3

>merge|NC_014103|3|1178258-1178467|CRT
AGTAGAACGGCGAGTAGAGCGGCGAGTAGAACGGCGAGTAGAGCGATAAGTAGAACGGCGAGTAGAACGGCGAGTAGAGCGGCGAGTAGAGCGATAAGTAGAACGGCGAGTAGAGCGGCGAGTAGAGCGATAAGTAGAACGGCGAGTAGAGCGGCGAGTAGAGCGATAAGTAGAACGACGGCTAGAGCGACGAGTAGAACGGCGAGTAGA

>NC_014103|3|1|1178258-1178467|CRT
AGTAGAACGGCGAGTAGA	GCGGCGAGTAGAACGGCGAGTAGAGCGATA
AGTAGAACGGCGAGTAGA	ACGGCGAGTAGAGCGGCGAGTAGAGCGATA
AGTAGAACGGCGAGTAGA	GCGGCGAGTAGAGCGATA
AGTAGAACGGCGAGTAGA	GCGGCGAGTAGAGCGATAAGTAGAACGACGGCTAGAGCGACG
AGTAGAACGGCGAGTAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013082180.1|1177213_1178011_-|VOC-family-protein	unknown	unknown	gnl|CDD|379203
NC_014103.1|WP_013082179.1|1175581_1177195_+|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl|CDD|349905
NC_014103.1|WP_013082172.1|1170857_1171265_+|DUF1259-domain-containing-protein	unknown	unknown	gnl|CDD|377846
NC_014103.1|WP_013082190.1|1187596_1188097_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|237292
NC_014103.1|WP_013082188.1|1185129_1186296_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224582
NC_014103.1|WP_013082176.1|1173483_1174638_+|amidohydrolase	unknown	unknown	gnl|CDD|349919
NC_014103.1|WP_013082183.1|1179457_1180627_-|MFS-transporter	unknown	unknown	gnl|CDD|340883
NC_014103.1|WP_013082170.1|1169546_1169882_-|DUF1049-domain-containing-protein	unknown	unknown	gnl|CDD|227703
NC_014103.1|WP_013055916.1|1181027_1182329_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NC_014103.1|WP_013082174.1|1172483_1172726_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082182.1|1178713_1179160_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
NC_014103.1|WP_013082184.1|1180801_1180996_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082175.1|1172929_1173436_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_014103.1|WP_013082189.1|1186676_1187459_+|aminoglycoside-phosphotransferase-APH(3')	unknown	unknown	gnl|CDD|366736
NC_014103.1|WP_013082186.1|1183516_1184215_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225818
NC_014103.1|WP_013082173.1|1171477_1172230_-|DUF45-domain-containing-protein	unknown	unknown	gnl|CDD|307807
NC_014103.1|WP_013082185.1|1182548_1183499_-|GHKL-domain-containing-protein	unknown	unknown	gnl|CDD|225827
NC_014103.1|WP_016763339.1|1170272_1170611_-|hypothetical-protein	unknown	unknown	gnl|CDD|378946
NC_014103.1|WP_013082187.1|1184390_1185128_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213233
NC_014103.1|WP_013082177.1|1174870_1175113_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013082180.1|1177213_1178011_-|VOC-family-protein	gnl|CDD|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	2.82954e-26
NC_014103.1|WP_013082179.1|1175581_1177195_+|M20/M25/M40-family-metallo-hydrolase	gnl|CDD|349905	cd05654, M20_ArgE_RocB, M20 Peptidase arginine utilization protein, RocB. Peptidase M20 family, ArgE RocB (arginine utilization protein, RocB; arginine degradation protein, RocB) subfamily. This group of proteins is possibly related to acetylornithine deacetylase (ArgE) and may be involved in the arginine and/or ornithine degradation pathway. In Bacillus subtilis, RocB is one of the three genes found in the rocABC operon, which is sigma L dependent and induced by arginine. The function of members of this family is as yet unknown, although they are predicted as deacetylases.	0
NC_014103.1|WP_013082172.1|1170857_1171265_+|DUF1259-domain-containing-protein	gnl|CDD|377846	pfam07485, DUF1529, Domain of Unknown Function (DUF1259). This family is the lppY/lpqO homolog family.	3.31709e-43
NC_014103.1|WP_013082190.1|1187596_1188097_+|MerR-family-transcriptional-regulator	gnl|CDD|237292	PRK13182, racA, chromosome-anchoring protein RacA.	2.44248e-26
NC_014103.1|WP_013082176.1|1173483_1174638_+|amidohydrolase	gnl|CDD|349919	cd05669, M20_Acy1_YxeP-like, M20 Peptidase aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2. Peptidase M20 family, aminoacyclase-1 YxeP-like subfamily including YxeP, YtnL, YjiB and HipO2, most of which have not been well characterized to date. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as in the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney suggest a role of the enzyme in amino acid metabolism of these organs.	0
NC_014103.1|WP_016763339.1|1170272_1170611_-|hypothetical-protein	gnl|CDD|378946	pfam12788, YmaF, YmaF family. This family of proteins contain 6 HXH motifs and is named after the B. subtilis YmaF protein. It seems likely that these are involved in metal binding. The function of this protein is unknown.	3.79215e-10
NC_014103.1|WP_013082170.1|1169546_1169882_-|DUF1049-domain-containing-protein	gnl|CDD|227703	COG5416, COG5416, Uncharacterized integral membrane protein [Function unknown].	7.35025e-18
NC_014103.1|WP_013055916.1|1181027_1182329_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.63684e-147
NC_014103.1|WP_013082188.1|1185129_1186296_+|ABC-transporter-permease	gnl|CDD|224582	COG1668, NatB, ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism].	6.99263e-33
NC_014103.1|WP_013082182.1|1178713_1179160_+|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.87152e-09
NC_014103.1|WP_013082175.1|1172929_1173436_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.85883e-11
NC_014103.1|WP_013082189.1|1186676_1187459_+|aminoglycoside-phosphotransferase-APH(3')	gnl|CDD|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	3.54605e-20
NC_014103.1|WP_013082186.1|1183516_1184215_-|response-regulator-transcription-factor	gnl|CDD|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	2.02219e-43
NC_014103.1|WP_013082173.1|1171477_1172230_-|DUF45-domain-containing-protein	gnl|CDD|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	6.65255e-21
NC_014103.1|WP_013082185.1|1182548_1183499_-|GHKL-domain-containing-protein	gnl|CDD|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	5.11628e-27
NC_014103.1|WP_013082183.1|1179457_1180627_-|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.45274e-58
NC_014103.1|WP_013082187.1|1184390_1185128_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213233	cd03266, ABC_NatA_sodium_exporter, ATP-binding cassette domain of the Na+ transporter. NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.	7.03756e-106

Protein sequences

>NC_014103.1|WP_013082180.1|1177213_1178011_-|VOC-family-protein
MHLSFDHLVHFSPDPISAQKELNEYGINVIKGGTHEKWGTFNTLAYFHLSYIEWLGLRDITLAQTVTDNDLIEQLVNEHTPFGHFGRFALRTDDMDLLIKELQSKSYAVKGPVAGSRQTTDGEKLQWKMCFIEADHDSLPLPFFIEWGEPEEKRKPKLAALSSHQAGQLQLKNIYCAVHNLEESISKWTKLLDVQAGEIYKDSLLDARCQKLYVNGGNLIFCSGTQGVVHHTLKKVGERPFLVELDHALTPQQITVQGASFKFNK
>NC_014103.1|WP_013082179.1|1175581_1177195_+|M20/M25/M40-family-metallo-hydrolase
MSNKTSLYQTKAQLKKLVSELVSIPSVTGTMAEVEMAESIASYLLKLPYFQKNEQVELHSTGDGRSIVTAFVQGKNTNKTVVLVSHYDVVDVQDYGQWKKDAFHADTLTSTFYNHMEQVPAHVQKDMIKGDWLFGRGTMDMKAGIALHISMVERACNGEFDGNILLLSVPDEEVNSLGMRKAVPVLLELARKHQLDFSLMLNAEPVFSRYPGDQTNYVYSGSIGKIMPSFLCYGKETHVGEPLAGLNANLLASYLTKEIELNVDFCEKVRDETSPPPTVLIQKDLKEEYSVQVPHSAVVLFNLFMLNRSLKEVTDLLLKSADKAALNVKKHYNKAARQYTAGMEGSSLDVNVWTYEELYTHAVQQHGEKYVQEMEEALLAQEDDDRNKTIKLVNTLAGLCKEAAPMIVLFFTPPFYPAVCSHDDPFVQGVLSNVQAAAKEQFQVELVEQSYFGGISDLSYASLQHPLHTFNTLVANMPLWNKGYHIPLEELEELKMPVLNIGPLGRDAHQWTERLDVQYSFEILPHFIYQAIKEAQK
>NC_014103.1|WP_013082177.1|1174870_1175113_+|hypothetical-protein
MSHTAVAAHTGEKALKEAVKLLGKHYQVAYRELETFYEIVVENHVRTYAVGIDIKDIQKANELEIYSSCCSKLERVGCLL
>NC_014103.1|WP_013082176.1|1173483_1174638_+|amidohydrolase
MTDQLLLNELIDIRRELHRFPELSMKEYETTKRIKKWLKHYDISIADAFQLDVGAVAEIVGGKPGPTIAIRADIDALPIEEKTNLPFASEVNGVMHACGHDFHTASIIGAAILLKERQQELCGTVRFIFQPAEETASGAKMLVEKGVLEGVEAIFGMHNKPDLPVGTIGIKSGPLMASVDRFEIDIKGVGGHAGIPEKTVDPIAAAGQIVTSLQTIVSRNLSPFQNVVVSITQIHGGSSWNVIPDKVTLEGTVRTFQEEAREKIPGLMKRTAEGIGAAFGASVDVKWYPYLPVVNNDDTLEKLAINAAENLSYQVVEAEQSPGGEDFAVYQQHVPGFFVWMGTAGEYEWHHPSFSLNEEALLVAASYFANLSFHFLNSFYYRKN
>NC_014103.1|WP_013082175.1|1172929_1173436_+|GNAT-family-N-acetyltransferase
MKNEFRLATNEDADNLLNLTLQAYKPIRELGIPFLAATADLALVKKNISQNLCYVYEEEKRIAATVSIRMPWGEHPGPFAVPHLWWFAVDPSFARKGVGSKLLHRVEEEVIKNTFKSPGVSLGTAKEHPWLVEMYERKGYVQAKEKHLAEGYTTVFLYKKFNKVHSLS
>NC_014103.1|WP_013082174.1|1172483_1172726_+|hypothetical-protein
MKNKKSVSKFTCEMLYMMVITLTVIEVTNYYLILKQEQAASIMLVITFLFAFLTTTVFYFIIRRSIMAVENLTKVMKGVS
>NC_014103.1|WP_013082173.1|1171477_1172230_-|DUF45-domain-containing-protein
MYTYQTGNQTIDYKIEVVPNRTDITVQVCDKEGVKVIIPRGLNENNVRSIIARKATWILKQLNGSQPAEEKPAAPKKEAVKKETAKKEAPKAAASAAKTGSFEEGDKFPYLGRQYRLNIVRGDVAKAEMTFRAKFIATVPESWNEQQTNEGIGQLLTEWYQGRAGEKFQEALKSVKKAADNAPESVKWDELGEEYATTQDNTIVLNWRLLTAPLATIEYVIASQFTNADELFEDAAERKQWLSDNTLNAF
>NC_014103.1|WP_013082172.1|1170857_1171265_+|DUF1259-domain-containing-protein
MSWENKKSLCQEFARILGGQGSLDENGVCLVQKFRTIRFKILGRPTRSPLVTPQFFTFEDLDSKGRALNLGETVLLQEEVNPLLTELRKRDIKVTAVHNHWLFEEPRAMYMYFESVEPPLDFARKVREAFRVLKG
>NC_014103.1|WP_016763339.1|1170272_1170611_-|hypothetical-protein
MKKIGKDDFVSGFVPHHNHGSVDYTSVASGHVHQCLDVTSPPIQSEDGSHIHYTEGYVVFEDGHTHHYKAYSGPAIPIGNGMHVHYYDFYTSEDNQHRHHVKGVDHPAPGDR
>NC_014103.1|WP_013082170.1|1169546_1169882_-|DUF1049-domain-containing-protein
MKGQSFFILGLIFALIIAVLAVINNDPVQFNYVFGSQKWPLILIILTTAVFGGVVAASLSFVKIVQLRGQVKQKNKRIAELEEEIKQYKPVEPVVEEEPTQPATRTERAQL
>NC_014103.1|WP_013082182.1|1178713_1179160_+|GNAT-family-N-acetyltransferase
MPQILEHQRVDIALQIVAVQVEAYQEEARLIDFSDIPQLTESKEDIMKSKEVFIGEMIEGKLAGVLSFEIKNERLTICRLVVRPRYFRKGVGSRLLTHVFQRYSKCEYIVSAAERNTPAIKLYEAHRFSIIKRTAAADNLVLVTMKRD
>NC_014103.1|WP_013082183.1|1179457_1180627_-|MFS-transporter
MNKQLGTLMFVIFMVFVGFGVIIPIVPEVIRATGASTVNLGILMASYSIASFITAPFWGKLSDIKGRRPILLWGLLGFSASFFLFSVAENSLTLMYTSRIIGGLFAGAVIPCAFAYASDSTDEENRTKAMGLLGMSIGLGFIFGPALGGVLSSFGLFVPFVISGILSLIMTAFSFFTLKESLRKESADKVQTSRWHDFTSDFQGAMKYLYVLSFLATFTLAGLEATFQFFQIAKINATPTTIGWMFMASGLTQALIQGGVLQRFKKGNEKKLMAIGLLVSAIGFTSILLSSSAVNATLFLCIFTAGNALIRPCVLSLITMRTKVGYGSASGLTASMDSLGRIFGPLLGAFAFKLNMTLPFIIGAVVTLAALLLIQRHTALDYSEQTLSS
>NC_014103.1|WP_013082184.1|1180801_1180996_+|hypothetical-protein
MPIWIVFAGIIGGLLGFGALVDYIAKKRSIELDPEEGIKNASDAEQIYVENYLYQTKENNNHFQ
>NC_014103.1|WP_013055916.1|1181027_1182329_-|NCS2-family-permease
MFKLKEYNTDAKTEILAGITTFLTMIYIVIVNPVILSSAGVPFDQVFTATIISAVVATLWMALAANYPIAIAPGMGMNAYFAALVVGSNGSIDYATAFSAVFVAGIIFIILSLTSFREKLIEAIPNNLKHAISAGIGLFIAFIGLRSAGIIVANKSNLIGLGDLQSEKVVLTLIGLAITIILYTLNVNGALFFGMIITGLIAFFRGQLSFDKGLFASPHLPDGLMISNPFAAFGDVIHHDLYTVVFSFLLVTIFDTTGTMVGVAQQAGLMKGNKMPRVRQALLADSFGTTIGALFGTSPTTAYVESSSGVAAGGRTGLTGVTVAILFIVAAFFSPVVSSVSGVAAITSPALIIVGSLMMGAVAKINWNDFDEAFPAFLVVLAMPLTSSIATGIALGFISYPLMKLVKGKGKQVHPLVYVFAVLFLYQLIFLPH
>NC_014103.1|WP_013082185.1|1182548_1183499_-|GHKL-domain-containing-protein
MKLFYTLVLLTVFVLLFFKDLPVSLHLLLSSFIIGSFFIWRKKYQTAPSLTIKKAIVLTSFFLLLFSLSSPFSIALTVIAMIGYMTDMFSSYQQYIFVTNRESSASREIQKNNELFQALRAERHDFIKHVSAVSYLLETNQRQQAQEYIQDYVEALNDTHSYIQGEHSHVASVVHQSKNQAHTWGIHMNVQLNSPLSQLPLKHLDQMNLIMNLLHNALEAAHSSEKKEITVSSMIRSGIYILEVSNSTAPLSRERQDHLFTSFHVTEKKERHEGLGTWIISELVSNYHGRLEYTYNDLTLSIKIKFPIVVSSKQAT
>NC_014103.1|WP_013082186.1|1183516_1184215_-|response-regulator-transcription-factor
MKVGLVDDHSYDLEKLRISLEREDDIDILFSTSSAEEAYNEIRKNEIDLLITDIEMPKLSGYELADFINAYALDIQVIFVTGHSGFAVHAFELNVLDYIMKPYSKERLLKGIQRFHQKKQSTDTRDKLILKQKTEIQVLNKQDIIFAERTGRSTTIITTNGEFSTYQSLNEIEKELTASHFLRSHRAFIINISYIQNFSLYTKHSYSVMFQSTEKTALITKTNLDILQKEYF
>NC_014103.1|WP_013082187.1|1184390_1185128_+|ATP-binding-cassette-domain-containing-protein
MIEIKGVTKYFKEKKQTIAAVQDIHVTIAQGEIVGLLGENGAGKTTLLRMLSTVLEPSEGNMFIHGINIHKQPDKIKQKIGVLFGGETGLYDRLTARENLAYFAKFYGMSKHETKIRIEELAKRFGMKDYLDRRVGGFSKGMRQKVAIARTILHNPDVILFDEPTTGLDITSANMFRELIKSLQREGKTIVFSSHIMEEVEMLCQSIIMIHKGKMIYQGTNEQLYKEEESTDLNYIFMSRIVRGA
>NC_014103.1|WP_013082188.1|1185129_1186296_+|ABC-transporter-permease
MIWHIYKKELIDCLRDRKTIIFSVLIPIILNVGIIFFADKMMASDQIDSMSVAVTKNSDASVIDWLKNNDNIKVIESKNPLSAVEQGKALAALKIPGNFSSEMRNMKSPEVTVYIDSSSMNSGATADYIQNILNKHREAIVTERLGQLNVNSQTIAPFNVVEKGVSKEDDGSLTMIAMFAPMIIIMGVLGGILPSANDIFAGEKERKTMEALLMSPVKRTQLLVGKWLTISTFGIISGLLSTLAFVLSVRYLTTVLNNALQLKGHFTTFIFSFLVSLTLLALLGAMVLCILSLLASSVKEAQSYTSQIMMVAILPYFLLMGKSVHELQPSGFLIPIYNVFALMKQLLYGVYDMQSLAYTIGSLSVCTVVLFTIGYTMFTKSRWVLGKG
>NC_014103.1|WP_013082189.1|1186676_1187459_+|aminoglycoside-phosphotransferase-APH(3')
MHPIIVEEIPDSIKKYVKQIEKVTFPKQGCTSDVGILHTAKGRYVLKRTKGEKYRKWLYKEYYVLKNIQALAECRSPIVYKFVQTAEQSWLLLEFFEGQTVREYLEKEDNEKKREHIVYEMGHLLARIHDAKCPKRLVSKQLWIHRMLQEAEYNLIHYKVDGNQQLLKQLQKQNMIYKQEVLIHGDYTIDNVLVHDGRITAVIDWSGGTLGEARYDMALAVRFEDGIFTGKERACFFKGYGKQISQSEFCYFAEGLYEFF
>NC_014103.1|WP_013082190.1|1187596_1188097_+|MerR-family-transcriptional-regulator
MTMKTVDVAKSLGIHPSTVLKWVKMANIELERNESGHCEFTEKNIEALRNFQKNRNRQAVVKVVEKVVEKEEVVISDERAQDMQKQLDQLFLRLIENEKRTEEKAGEVVTFQILEHRSEIDRLNKVITKLENRVVELESQLKSEDSLKGKKPVPRWRSFLTGIFSY

Crispr_ID: NC_014103_4

• CRISPR_ID: NC_014103_4
• CRISPR_location: 1377392-1377820
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of NC_014103_4

Consensus_repeat	Method
GGCGAGNAGAACGGCGAG	CRT

spacers of NC_014103_4

>4.1|1377410|45|NC_014103|CRT
AGCGGCGAGTTCCACGAGAAGAACGGCGGGTACTTCGGGAAGAAC
>4.2|1377473|42|NC_014103|CRT
AAGAGCGGCGAGTAGAACGGCGAGTAGAACGGCGAGAAGAGC
>4.3|1377533|54|NC_014103|CRT
AAGAACGGCGAGAAGAGCGGCGAGTAGAACGGCGAGAAGAGCGGCGAGAAGAGC
>4.4|1377605|18|NC_014103|CRT
AAGAGCGGCGAGAAGAGC
>4.5|1377641|30|NC_014103|CRT
TAGAACGGCGAGAAGAGCGGCGAGAAGAGC
>4.6|1377689|18|NC_014103|CRT
AAGAGCGGCGAGTAGAAC
>4.7|1377725|18|NC_014103|CRT
AAGAGCGGCGAGTAGAAC
>4.8|1377761|42|NC_014103|CRT
AAGAACGACGAGAAGAACCACGAGAAGAACCACGAGAAGAAC

CRISPR arrays and Neighbor proteins around NC_014103_4

CRISPR arrays

The CRISPR arrays of NC_014103_4

>merge|NC_014103|4|1377392-1377820|CRT
GAAATTAAGAACGGCGAGAGCGGCGAGTTCCACGAGAAGAACGGCGGGTACTTCGGGAAGAACGGCGAGTAGAACGGCGAGAAGAGCGGCGAGTAGAACGGCGAGTAGAACGGCGAGAAGAGCGGCGAGTAGAACGGCGAGAAGAACGGCGAGAAGAGCGGCGAGTAGAACGGCGAGAAGAGCGGCGAGAAGAGCGGCGAGTAGAACGGCGAGAAGAGCGGCGAGAAGAGCGGCGAGTAGAACGGCGAGTAGAACGGCGAGAAGAGCGGCGAGAAGAGCGGCGAGTAGAACGGCGAGAAGAGCGGCGAGTAGAACGGCGAGTAGAACGGCGAGAAGAGCGGCGAGTAGAACGGCGAGAAGAACCACGAGAAGAACGACGAGAAGAACCACGAGAAGAACCACGAGAAGAACGACGAGAAGAACCACGAG

>NC_014103|4|2|1377392-1377820|CRT
GAAATTAAGAACGGCGAG	AGCGGCGAGTTCCACGAGAAGAACGGCGGGTACTTCGGGAAGAAC
GGCGAGTAGAACGGCGAG	AAGAGCGGCGAGTAGAACGGCGAGTAGAACGGCGAGAAGAGC
GGCGAGTAGAACGGCGAG	AAGAACGGCGAGAAGAGCGGCGAGTAGAACGGCGAGAAGAGCGGCGAGAAGAGC
GGCGAGTAGAACGGCGAG	AAGAGCGGCGAGAAGAGC
GGCGAGTAGAACGGCGAG	TAGAACGGCGAGAAGAGCGGCGAGAAGAGC
GGCGAGTAGAACGGCGAG	AAGAGCGGCGAGTAGAAC
GGCGAGTAGAACGGCGAG	AAGAGCGGCGAGTAGAAC
GGCGAGAAGAACCACGAG	AAGAACGACGAGAAGAACCACGAGAAGAACCACGAGAAGAAC
GACGAGAAGAACCACGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013082348.1|1387832_1388000_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082336.1|1375937_1376108_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082347.1|1387175_1387721_-|YhcN/YlaJ-family-sporulation-lipoprotein	unknown	unknown	gnl|CDD|131944
NC_014103.1|WP_013082340.1|1379324_1380467_+|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NC_014103.1|WP_013082331.1|1369565_1370057_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013056112.1|1375011_1375266_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013056130.1|1388287_1388491_+|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_014103.1|WP_013056116.1|1376658_1377072_+|YppG-family-protein	unknown	unknown	gnl|CDD|372950
NC_014103.1|WP_013082344.1|1384185_1384452_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082332.1|1370092_1372939_-|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|273955
NC_014103.1|WP_013082343.1|1382679_1383861_+|PLP-dependent-transferase	unknown	unknown	gnl|CDD|366438
NC_014103.1|WP_013082333.1|1373002_1373602_-|Holliday-junction-resolvase-RecU	unknown	unknown	gnl|CDD|235015
NC_014103.1|WP_013056115.1|1376234_1376429_-|YppF-family-protein	unknown	unknown	gnl|CDD|290882
NC_014103.1|WP_013082339.1|1378108_1379194_+|CotH-kinase-family-protein	unknown	unknown	gnl|CDD|227642
NC_014103.1|WP_013082337.1|1377103_1377250_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082342.1|1381550_1382696_+|PLP-dependent-transferase	unknown	unknown	gnl|CDD|366438
NC_014103.1|WP_013082341.1|1380531_1381194_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082345.1|1384514_1385174_-|SIMPL-domain-containing-protein	unknown	unknown	gnl|CDD|225516
NC_014103.1|WP_013082334.1|1373675_1374671_+|DUF2515-family-protein	unknown	unknown	gnl|CDD|371209
NC_014103.1|WP_013056113.1|1375311_1375662_+|YppE-family-protein	unknown	unknown	gnl|CDD|378052

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013082333.1|1373002_1373602_-|Holliday-junction-resolvase-RecU	gnl|CDD|235015	PRK02234, recU, Holliday junction-specific endonuclease; Reviewed.	1.83089e-115
NC_014103.1|WP_013082347.1|1387175_1387721_-|YhcN/YlaJ-family-sporulation-lipoprotein	gnl|CDD|131944	TIGR02898, Uncharacterized_lipoprotein_YlaJ, sporulation lipoprotein, YhcN/YlaJ family. YhcN and YlaJ are predicted lipoproteins that have been detected as spore proteins but not vegetative proteins in Bacillus subtilis. Both appear to be expressed under control of the RNA polymerase sigma-G factor. The YlaJ-like members of this family have a low-complexity, strongly acidic 40-residue C-terminal domain that is not included in the seed alignment for this model. A portion of the low-complexity region between the lipoprotein signal sequence and the main conserved region of the protein family was also excised from the seed alignment. [Cellular processes, Sporulation and germination].	3.2174e-36
NC_014103.1|WP_013082340.1|1379324_1380467_+|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.00934431
NC_014103.1|WP_013056116.1|1376658_1377072_+|YppG-family-protein	gnl|CDD|372950	pfam14179, YppG, YppG-like protein. The YppG-like protein family includes the B. subtilis YppG protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 115 and 181 amino acids in length. There are two completely conserved residues (F and G) that may be functionally important.	1.94961e-16
NC_014103.1|WP_013082332.1|1370092_1372939_-|PBP1A-family-penicillin-binding-protein	gnl|CDD|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_014103.1|WP_013082343.1|1382679_1383861_+|PLP-dependent-transferase	gnl|CDD|366438	pfam01053, Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme. This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.	0
NC_014103.1|WP_013056115.1|1376234_1376429_-|YppF-family-protein	gnl|CDD|290882	pfam14178, YppF, YppF-like protein. The YppF-like protein family includes the B. subtilis YppF protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There is a conserved LLDF sequence motif.	2.20049e-27
NC_014103.1|WP_013082339.1|1378108_1379194_+|CotH-kinase-family-protein	gnl|CDD|227642	COG5337, CotH, Spore coat assembly protein [Cell envelope biogenesis, outer membrane].	2.53476e-98
NC_014103.1|WP_013056130.1|1388287_1388491_+|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.31107e-32
NC_014103.1|WP_013082342.1|1381550_1382696_+|PLP-dependent-transferase	gnl|CDD|366438	pfam01053, Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme. This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.	0
NC_014103.1|WP_013082345.1|1384514_1385174_-|SIMPL-domain-containing-protein	gnl|CDD|225516	COG2968, COG2968, Uncharacterized conserved protein [Function unknown].	3.70502e-34
NC_014103.1|WP_013082334.1|1373675_1374671_+|DUF2515-family-protein	gnl|CDD|371209	pfam10720, DUF2515, Protein of unknown function (DUF2515). This family is conserved in Firmicutes. Several members are annotated as YppC. The function is not known.	2.81953e-136
NC_014103.1|WP_013056113.1|1375311_1375662_+|YppE-family-protein	gnl|CDD|378052	pfam08807, DUF1798, Bacterial domain of unknown function (DUF1798). This domain is found in many hypothetical proteins. The structure of one of the proteins in this family has been solved and it adopts an all alpha helical fold.	1.48531e-35

Protein sequences

>NC_014103.1|WP_013082337.1|1377103_1377250_-|hypothetical-protein
MKKNKHQISTSSTTDIEEVKRLNAQSGLTYNEVFTLLGENYLKNQKKK
>NC_014103.1|WP_013056116.1|1376658_1377072_+|YppG-family-protein
MYTSKHYPYYEQHQPERFDLSQVHPFPQYHQQPWTEAYMPQHPYAQQQMPFGPQQIPYMNGMYQQPMYNNAGAPFNPYPKAQQQKPQPSQFQSLMSQFKSSDGNYDMNKMMNTAGQMMGAMNQLTSLVKGFSGIFKV
>NC_014103.1|WP_013056115.1|1376234_1376429_-|YppF-family-protein
MYVNELQEAFIAVKQYEPQSSNELLDFAQQQYLKGFLTPMNYKAAVRELEQIGATKPDFSAQDD
>NC_014103.1|WP_013082336.1|1375937_1376108_-|hypothetical-protein
MSRGKHFDHKKQGQSAATKTNNAVASKHTEKVDYHIDTVASQDHPAVSIQSQKDFD
>NC_014103.1|WP_013056113.1|1375311_1375662_+|YppE-family-protein
MNEDVKKSTEIMFQYNEVAVERLASIQQEENYEVKFFEEVKPYGDIFFKELDEWASLVTEWLKKERPKYIHVNQVETLKENLQNVVLQSFYPETREKRFKKMYHSNKYVLESILNN
>NC_014103.1|WP_013056112.1|1375011_1375266_+|hypothetical-protein
MKQSMVKTSEMMTLLDSLLEQVDLVDKTMSTSINEAFTHCEETYMEQVHRIDQSLQEIEVAVYESMPSETEWNRSRREMVLHTV
>NC_014103.1|WP_013082334.1|1373675_1374671_+|DUF2515-family-protein
MKEDEEMSLNSSEQALLTAIKKTTDKLNIDNISRTQAYATFYHRYPEVKWAFLASMVSRNAGWNMCDLQGKIMKKALSKQTRDLLFLTYERANWLIFKDAFPQLLLYAVSRKKHVSYLHLLPYLNVSSFIEEKWRQFMQKPCELELIHALIVNEQHVIQKPVIEQPFYQDKVFKSMLFFFQDIFHFSSVLFPTTKGELYGCSVHDFTKVNNRIDLGKKLAALLFHEKYYPLFYEFSLKTKHTGSRYDYEQYFVNETSCRTPALRKVYPAIRHHEKKREEWFLTKKEEQKLMKKPSFPKKVHFTKWYLQKQKQLYILMKLAQVFNVNKNGHK
>NC_014103.1|WP_013082333.1|1373002_1373602_-|Holliday-junction-resolvase-RecU
MIRYPNGKAYKPLNTSSPSPKKLEASYSNRGMTLEDDLNETNEYYVSKGIAIVHKKPTPVQIVKVDYPKRSAAVIKEAYFKQASTTDYNGVYKGKYLDFEAKETRNKTSFPLRNFHEHQIEHMKQIVKQNGICFVILMFSTLQEIYLFEAQFLFPYWDAMKKDGRKSIPKADIEKKGHFIELGYHPRIDYIKTIDKLYF
>NC_014103.1|WP_013082332.1|1370092_1372939_-|PBP1A-family-penicillin-binding-protein
MSDNYRSREERRRAMNDNKPEGKSQGKPKKKKKGGLFRKIVAAVLLIGIIGLIAGVGTFFAMISDAPKVDDSVLKNSFSSKVYANDGKTVVKEIGAQKRTYVQYDEIPQVVKNAFIATEDVRFYKHHGVDFYRIGGALMANFKNGFGAEGGSTITQQVVKNSFLSPKKTVKRKVQEMWLAYQLERKYSKQQILEMYLNKIYFASGEVYGIERAAEKFYGVKSVKDLTLDEAAMLAGLPKAPTTYNPVTNPENATKRRNTVLNLMAKNGFITQAEADKAKQVDVQAHLAKQTESTSKYDVFIDQVIEEVKKKTDADPFSAGLEIYTTLDTNAQDYVDDVMNNKVVNFPNDKFQAGLVVVDNETGGIQAIGGGRNRVSGGLNFATNMRRQPGSTIKPILDYGPAIENLKWSTGQPLKDEEYHYSNGTPIRNFGRNYKGWVSAREALGRSLNIPALKAFQATGADKAKEFATGLGLKLDEEDGEAYSESYSIGGFRTGVTPLQMAGAYSAFANEGMYNAPHTVTKVKFPDGTEIDLTPKSKRAMQDYTAFMMTDMMKSVVNESYGTARAVRTPGLEIAGKTGTSNFSAAEKQRYNIPDAGEKDVWFNGFTPNYTISVWTGYETAKDGYILSPNETGMAKNIFKHVITHISEGKPKGSFKQPDSVVERSVEKPTGKDLKRPSGSTPSSLITKEYFVRGTAPTKVSQTFVKKEKEEKKEEKEEKKEDKKEKKDNKNVKPKITASYSGGAISVNWSASNAAGDTTFTVTMSSPNGSEQLASGAGAGGKTISNPAPGATYSFTVTTNTGESASSSVKVPDSSDQATEDDSTKPEDDGTTDDNQKEDNSNTDQNNGSDQGDDSSTQPDDNQNSNNGSNNGSNNGGNNSGNTDNNNNDSGNANDGNSNNNNNNGGTTTPPADNGGSDSGSQTPPTTPATPSTPSTPATPQQEPTTEN
>NC_014103.1|WP_013082331.1|1369565_1370057_+|hypothetical-protein
MLPIEVPSHFICEPFYSKEDRILEVGGRNYFAYDILYDVHKETKTPWRDVQKNIRPFFEKWETQREELHTLFSQRKAKEAAPCMKQAVAMYISLLFWINGQPVRRLNRLQEDIADLTYKPINCAERLMFLLQRVSSYQAYIQLTELFNELRKQYAKMLILHKK
>NC_014103.1|WP_013082339.1|1378108_1379194_+|CotH-kinase-family-protein
MKQKEIPQYALFVNVKDLKEMHRDIWSEEVVQATMKFNKKRYDIDLLLRGSHIRKMKKKSYFIEFYSPKIFQHSKEIHLNAEYKDPSLMRNKLSLDFFSSLDVLSPHSQFVTLTINGKNEGVYLQLESVDELFLKKRNLADGSIFYAVDGDANFSLMSDLDKKPKTSLLSGYEDKVVKQGDKEKLEQFIFNVNTWTNTEFEQNIEKYLNVDRYLSWLVGIICMQNYDGFVHNYALYRNHDSGRFELIPWDYDATWGRDVNGKVMEGDYVRAQGFNTLTARLLAVDGIKKRYIKKMNNVLNNQFTVEYMKPIVYQMHEELKPYILKDPYVKNNIEQFYEEPAFILSFIKDRTAYIKNNLLTF
>NC_014103.1|WP_013082340.1|1379324_1380467_+|hypothetical-protein
MENYYYYYGQNQGQNSNPNRKRSHSKNTNRPDKGYSSQFKPLKGRMVTVYRGGPESKTGYLLDVQSDYLILAVESDNNNNNDENNNEGNSNQNNQNNQNNQNNQNNQNNQNNQQEYTVVYYHLSHVKSITEDAVSNSAQTFTGFDNEGTLELYRGKTFASTLSLLKSKYVQINQGGPEKKAGQLLDVLGSSESAYLVLLSEDDGVVYINVEHVKSISEYQNDNNNNNNNNNQMNNQFATNQEPTYMKSKTFNNLFTHLSHKWVSINGGGPEAVEGVLVQSRNGTFTLVQDNQVLRLQPRHVKTICVGAKGSFKQNNNQDDEQKEENTNTEDGGSAEGVSEGRTGRSRTGSYSSRKSRRTDSHSSASREQVIQTKNYRWKA
>NC_014103.1|WP_013082341.1|1380531_1381194_+|hypothetical-protein
MSINHYINKIVEVDISGNTKFVGRLVDLGLDVMILYNGHDYLYIPLLHMHRLREVSEEDYTVLREIEENLIEESQRISYRNILQQAKGKFIEIYVTGGKSLHGYITSVLNDYLVFYSPVYKNVFVSLHHLKWLTPYSNELTPYSLSDKELPVRPASAPFVRNFEEQLKKYENQLVVLDLGDQSEKIGVLKEVSNNIVELITANGESIYWKLAHVKSVHLP
>NC_014103.1|WP_013082342.1|1381550_1382696_+|PLP-dependent-transferase
MKIETLLVRSGVGRDPSTGSITTPIYQASTFAHPALGQSTGFDYARTANPTRTALEEAIAALEKGEVGAAFASGMAGVMAVLALFKNGDHLIVSEDLYGGTYRVLNEIFSEQGITVSYVNTAHLEQVKDALRPNTKALFIETPTNPMMHVTDLPEAIALAKQHDLLTIVDNTFMSPYYQRPLELGADIVIHSASKYIGGHNDVVAGLVVARCSSLGEKIRFYQNAAGAILGPQDSWLLLRGVKTLALRMEKHNENALKIANWLTAHDLVEKVYYPGLETHPGYEIMKKQATGFGGMISFAVSHPDIVSTLLENVKVITFAESLGGVESLMTFPARQTHADIPEEIRNRVGVTNCLLRLSVGIEHADDLIKDLKEAFDAYHQ
>NC_014103.1|WP_013082343.1|1382679_1383861_+|PLP-dependent-transferase
MHTTNNKHRFGTNLIHANTGIDGHFGAVNVPIYQVSTFNQEDETNNGRYDYSRSGNPTREALENTIAQLENGYAGFAFSSGMAAISSVLSIFESGDEILVSHDTYGGTYRVLTRLFSKFGIKTTFVDTTKVEKVEEAITKDTKAIYIESPSNPFLQVTDIKAVASLAKERNVLTIVDNTFLTPYLQQPIDLGVNIVIHSATKYISGHSDVIGGLVVVSDEKLAEEVKFVQNAFGAILGPQDCFLLLRGIKTLKVRLDQQLKTALQFAKWLEEQSLVSRVYYPGLKSHPDHKLISEQANGYGAMISFQVQDEKVARHILQGVKLASIGVSLGAVESILTHPATMSHASIPKEVREEKGITDSLLRLSVGLEEFEDLKQDFNAVFQSLEEKALIK
>NC_014103.1|WP_013082344.1|1384185_1384452_-|hypothetical-protein
MTSEHLLAAYQTLWLNRSFASKQAMTSEDQLHEAIMKDLKDEMTHPRVRQTPYVKYHLGIKRILNSSLSSDEKVALTSLYTNLLDSCI
>NC_014103.1|WP_013082345.1|1384514_1385174_-|SIMPL-domain-containing-protein
MQHSYFPYEPTQQLRVDTQNREIKVIGEGTASAIPNEISMTIGTRTENRDVQEALKENSAVSNTLLQEIKKLGINDQQIETASFTINPKYDYSDGKSTLTGYEVQHLFRVRVQDVKQAGDVYNATFSSGANVAQDLQFHVTNDDKYEQEAISKALLNAKEKAFTIANTLQLPINQIPILIEEGPVYQSSGSSPKLLAASPPIQAQSLTVSASVKVTYTY
>NC_014103.1|WP_013082347.1|1387175_1387721_-|YhcN/YlaJ-family-sporulation-lipoprotein
MKKSFLFVVGCMTTLFLFGCSTADQGKDGVIDDDTVRNVTYENGNNKTKMNDVNDTQDVQRNEKEQYNQSGGMRVADVAADRIVALKNVKDANVIVTDHTAYVAAVLDDNKEGNLTKDMEHKIAHEVRKADGSVHRVFVSTNPDFVNRMNGYVDKLQTGKPVSGLVDEFSEVVRRVFPNSR
>NC_014103.1|WP_013082348.1|1387832_1388000_+|hypothetical-protein
MSGIQQSIFVLHTKEENHEETTTFALTSEEAKLLFETLQNKRKKIIDAHIDNMLT
>NC_014103.1|WP_013056130.1|1388287_1388491_+|cold-shock-protein
MATTGTVKWFNSEKGFGFIEVPGENDVFVHFSAIQSEGFKTLEEGQKVEFEIVEGQRGPQAENVVKL

Crispr_ID: NC_014103_5

• CRISPR_ID: NC_014103_5
• CRISPR_location: 1542126-1542208
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014103_5

Consensus_repeat	Method
TGATTTTTGGAAGTAGCTTCTCC	CRISPRCasFinder

spacers of NC_014103_5

>5.1|1542149|37|NC_014103|CRISPRCasFinder
GCCTTTTTCACCAATTTCTTGGTAAAACTCTTTGTCA

CRISPR arrays and Neighbor proteins around NC_014103_5

CRISPR arrays

The CRISPR arrays of NC_014103_5

>merge|NC_014103|5|1542126-1542208|CRISPRCasFinder
TGATTTTTGGAAGTAGCTTCTCCGCCTTTTTCACCAATTTCTTGGTAAAACTCTTTGTCATGATTTTTGGAAGTAGCTTTTCC

>NC_014103|5|3|1542126-1542208|CRISPRCasFinder
TGATTTTTGGAAGTAGCTTCTCC	GCCTTTTTCACCAATTTCTTGGTAAAACTCTTTGTCA
TGATTTTTGGAAGTAGCTTTTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013082482.1|1542807_1543539_-|ZIP-family-metal-transporter	unknown	unknown	gnl|CDD|223505
NC_014103.1|WP_013058452.1|1546209_1546419_-|alpha/beta-type-small-acid-soluble-spore-protein	unknown	unknown	gnl|CDD|365990
NC_014103.1|WP_013056278.1|1538726_1538879_-|YpzG-family-protein	unknown	unknown	gnl|CDD|372924
NC_014103.1|WP_013082487.1|1547821_1549063_+|MFS-transporter	unknown	unknown	gnl|CDD|236549
NC_014103.1|WP_013082484.1|1545540_1545762_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_155276310.1|1541206_1541353_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082489.1|1550815_1552276_+|YdiU-family-protein	unknown	unknown	gnl|CDD|234583
NC_014103.1|WP_013082476.1|1538539_1538680_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082481.1|1542485_1542710_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082478.1|1540997_1541138_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_080514719.1|1536371_1536998_+|LysE-family-transporter	unknown	unknown	gnl|CDD|280058
NC_014103.1|WP_013082485.1|1545919_1546120_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082473.1|1535968_1536205_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082475.1|1537125_1538469_+|amino-acid-permease	unknown	unknown	gnl|CDD|224038
NC_014103.1|WP_042452948.1|1549084_1550542_+|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl|CDD|224536
NC_014103.1|WP_013082483.1|1544000_1545386_+|amino-acid-permease	unknown	unknown	gnl|CDD|182694
NC_014103.1|WP_013082486.1|1546509_1547493_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380514
NC_014103.1|WP_013082477.1|1539106_1540780_-|ribonuclease-J	unknown	unknown	gnl|CDD|223668
NC_014103.1|WP_013082479.1|1541566_1541983_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082471.1|1534983_1535832_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293807

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013082482.1|1542807_1543539_-|ZIP-family-metal-transporter	gnl|CDD|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	1.43193e-13
NC_014103.1|WP_013058452.1|1546209_1546419_-|alpha/beta-type-small-acid-soluble-spore-protein	gnl|CDD|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	1.44763e-21
NC_014103.1|WP_013056278.1|1538726_1538879_-|YpzG-family-protein	gnl|CDD|372924	pfam14139, YpzG, YpzG-like protein. The YpzG-like protein family includes the B. subtilis YpzG protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 50 amino acids in length. There is a conserved QVNG sequence motif.	2.24591e-14
NC_014103.1|WP_013082487.1|1547821_1549063_+|MFS-transporter	gnl|CDD|236549	PRK09528, lacY, galactoside permease; Reviewed.	0
NC_014103.1|WP_042452948.1|1549084_1550542_+|glycoside-hydrolase-family-32-protein	gnl|CDD|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	1.314e-175
NC_014103.1|WP_013082489.1|1550815_1552276_+|YdiU-family-protein	gnl|CDD|234583	PRK00029, PRK00029, YdiU family protein.	0
NC_014103.1|WP_080514719.1|1536371_1536998_+|LysE-family-transporter	gnl|CDD|280058	pfam01810, LysE, LysE type translocator. This family consists of various hypothetical proteins and an l-lysine exporter LysE from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators. LysE exports l-lysine from the cell into the surrounding medium and is predicted to span the membrane six times. The physiological function of the exporter is to excrete excess l-Lysine as a result of natural flux imbalances or peptide hydrolysis; and also after artificial deregulation of l-Lysine biosynthesis as used by the biotechnology. industry for the production of l-lysine.	3.64148e-25
NC_014103.1|WP_013082475.1|1537125_1538469_+|amino-acid-permease	gnl|CDD|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	1.42977e-120
NC_014103.1|WP_013082483.1|1544000_1545386_+|amino-acid-permease	gnl|CDD|182694	PRK10746, PRK10746, putative transport protein YifK; Provisional.	0
NC_014103.1|WP_013082486.1|1546509_1547493_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380514	cd06291, PBP1_Qymf-like, ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs. This group includes the ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus metalliredigens (strain Qymf) and its close homologs. Qymf is a strict anaerobe that could be grown in the presence of borax and its cells are straight rods that produce endospores. This group is a member of the LacI-GalR family repressors that are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	6.37202e-108
NC_014103.1|WP_013082477.1|1539106_1540780_-|ribonuclease-J	gnl|CDD|223668	COG0595, COG0595, mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair].	0
NC_014103.1|WP_013082471.1|1534983_1535832_+|MBL-fold-metallo-hydrolase	gnl|CDD|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	7.36101e-72

Protein sequences

>NC_014103.1|WP_013082479.1|1541566_1541983_+|hypothetical-protein
MNLHDFVHGVDPTIKLVIEDEFPGTRCVGGKYVPSTHSIFLYEKDINIQCQHLFGSNECLESYQWIILAHELGHALDEDLLSLSAKFDQTDDIGLLYRIECNAWEIGEKLIPFINSELFSFIKDQSLAHYHKEMEKIS
>NC_014103.1|WP_155276310.1|1541206_1541353_+|hypothetical-protein
MSENKSSQYKEENKSTPSRPLEYKERTNQSQSTRQMLRSILEYSSRYR
>NC_014103.1|WP_013082478.1|1540997_1541138_+|hypothetical-protein
MSKQNKSKNQGVSSSAAAVDNVNKSILSNDIHTDELQKAKVSRHNK
>NC_014103.1|WP_013082477.1|1539106_1540780_-|ribonuclease-J
MSTNRNTLSIFALGGINEIGKNMYAVQYDDDIIVIDCGSKFPDESLLGIDLIIPDITYLQENREKVRALVVTHGHEDHIGGIPYLLKQLNLPIYATSLTLGLIDIKLQEHQLSAETELIEINEESEITLGNIPLSFFKTNHSIPDCLGIVFHTPEGAVVHTGDFKFDLTPVNDQYPDLHKMAKIGSEGVLALISESTNAERPGFTPSEKLVGKHVEEAFRKAKRKVIISTFASNINRVQQIVDAAIKTNRKLALLGRSMVNVVSVALEKGYLTIPEGMLIEPYEVHSLAPEQVAILCTGSQGEPMAALSRLASGNHRQVEILPEDTVILSAGPIPGNERNISRIVDSLFTLGAHVIYGSGSATGMHVSGHGYQEELKLMATLMKPKYFIPIHGEFRMLHHHSLLAESVGVEKENIFIINNGDIVDIKGGAAVQTRKIPAGNVYVDGFGIGDVGNAILRDRKQLSEDGMLVIVITLNKAEGKIVSGPDTISRGFVYTRDSEQLLKDVNRQVTKIVNQLQKAHVHQWSIMKKEIKTTLGQFLYNQTKRRPMILPVIIEV
>NC_014103.1|WP_013056278.1|1538726_1538879_-|YpzG-family-protein
MNDKNQVDQHSELFRHNWTRPKRSKSQVNGHTEMSQTNIILRSNAKAHRW
>NC_014103.1|WP_013082476.1|1538539_1538680_+|hypothetical-protein
MPKNKQTPSSQVDQKQVVDDKAKALRENNYEDGHIRKITQSGADGQ
>NC_014103.1|WP_013082475.1|1537125_1538469_+|amino-acid-permease
MKKKIGCGSQVEGKLKWWQLSLIGVGCIIGTGYFLGSSIAIKATGPSVLIAFLLAAVCTFIVFDALAKMSAQDPQKGSFRSYAKKAYGRWAGFSSGWVYWSSEMLIMGSQLTALSLFTRFWFDGIPLWVFASIYAVLGIAVVLIGTKGFERMENVFAVTKVAAILMFIVLASLALFGFLDEGAKQGMPRTISEVFPHGFLGLWGALLYAFYAFGGIEVMGIMTVRLEKKEDAPKAGRSMLILLGIIYIASLSLAILIVPFHDFHGNQSPFITALETYHLPFFPHVFNGAMIIAGFSTMSASFFSVTTMIVTLSEDGDAPALFSKQKKKKLQFPLPALLLTTAGLIVSIVLSLLLPGKIYEYITTAAGLMLIYNWFFILISFHRLIKQTVWDKVKQAVGLLLILLAVSGTLLESASRPGFFASLGFLIVISLVILKLRHKWKEEEAAS
>NC_014103.1|WP_080514719.1|1536371_1536998_+|LysE-family-transporter
MGAFFSYMLLGLSLAAPIGPINAAQLDKGIKNGFLHAWFLGIGATSVDALYMLVVYFGSVHFLSSDFMKTFLFSFGCFVLIYTGIEGLMSAGKITQHRNAKGDSVVKCFFSGFLISLTNPLTILFWLGIYGSVLAKTANTYETGQLILYSCAIFTGILCWDIAMAALASTFRRYLAATFLTAVSVISGLSLIGFGIYFGWQAVQQFII
>NC_014103.1|WP_013082473.1|1535968_1536205_-|hypothetical-protein
MNSYTHIKEALQLAEQAVYQGQMNLNGANFQNAQMHLTIVQQQINEQKKQASGDKELKRMEEHLRHLREAQQAIQQNF
>NC_014103.1|WP_013082471.1|1534983_1535832_+|MBL-fold-metallo-hydrolase
MNREMHGSSSTESFIPMSSIASGKGVEVAPDIYSYTTQIVNVCFIGNPDKENSFVLVDAGMPNSASMIIKEAEERFGKEKKPKAIILTHAHFDHIGSIIELVEKWNIPVYAHPLELPYVTGKKNYPTPDGTVEGGLVAKLSPLFPTEAIDLGSHVQALPDDGSVPHMPEWEWIHTPGHSPGHISLFRKQDLALIAGDAFVTTKQEYLLDVLEQELEISGPPRYLTTDWASAKRSVEVLQSLHPSVAVTGHGKPVSGEWLSTNLLKLTKNFDEIARPHYEKYV
>NC_014103.1|WP_013082481.1|1542485_1542710_+|hypothetical-protein
MSKYVEMDTASLRRKIQEYKELIWRVGPGSERTIEAVQEIQGMEKELKARNAEFEATDWKNFTQEIKENYDFTY
>NC_014103.1|WP_013082482.1|1542807_1543539_-|ZIP-family-metal-transporter
MWQAAMWGGISGSAVLLGALAAVFLPIGKKIIGYIMAFGTGVLIGASTYELLGDSVHNGGLKATSLGFLAGAVVFTFLDYLISRQGANKRKRSTKQMAASSSGIAIFIGTVMDAIPESIMIGASLIENATVSWLLVIAIFISNIPEGLSSTTGLVKSGFSKKKIFLLWAAVLFISAFSSWTGFVFLDHASETLMAAIAAFAGGGIIAMVGSTMMPEAYEEGGSITGLIAALGLLASLILDHFS
>NC_014103.1|WP_013082483.1|1544000_1545386_+|amino-acid-permease
MADKELKRGLESRHIQMIALGGTIGVGLFMGSASTIQWTGPSVLLAYAICGMFIFFIMRAMGEMLYMEPSTGSFATFGHKYIHPLAGYMAAWSNWFQFVIVGMSEIIAVGAYMHYWFPHLPAWVPGIIAMLILGTANLVSVKSFGEFEFWFAMIKIVTIILMIIAGLGLIFFGFGNGGDAIGLSNLWAHGGFFAGGWSGFFFALSLVIAAYQGVELIGITAGEAKDPKKTLTSAIQSIIWRILIFYIGAIFVIVTVYPWNELDSLGSPFVSTFAKVGVTAAAGIINFVVITAAMSGCNSGIFSAGRMLYTLGVNGQAPKFFTKISRNGVPIYSTLAVMIGLVIGVVLNYIAPPNVFVYVYSASVLPGMIPWFIILISQIRFRKAKGAEMDSHPFKMPFAPVTNYVTIAFLLMVLVGMWFNDETRISLIVGIIFLALVVISFYTFGINKRMIPDTENGQIKK
>NC_014103.1|WP_013082484.1|1545540_1545762_+|hypothetical-protein
MRSHRYIIKDSLKADEVARDLELQLDINRMSDVRILSVNAQNEILVQMQEENEEAGDVIDVFMKEYKTAEIIE
>NC_014103.1|WP_013082485.1|1545919_1546120_+|hypothetical-protein
MKVKKNGEGHVFFIILGGLFILIGTLFANTSVYFLISGWIAAVCCLGTSAVLKKGKTKSVSKEGEE
>NC_014103.1|WP_013058452.1|1546209_1546419_-|alpha/beta-type-small-acid-soluble-spore-protein
MANNKSSNNNELLVYGAEQAIDQMKYEIASEFGVNLGADTTARANGSVGGEITKRLVQLAEQQLGGGRF
>NC_014103.1|WP_013082486.1|1546509_1547493_-|LacI-family-DNA-binding-transcriptional-regulator
MKAKISDVAKIAGVSPTTVSRVLNNRGYISKETRENVYKAMKEINYFPNDIARSLFNKRTNLIGMIVPQTSNPFFGELAFHIESICASLNYKVLLCNSLNRIDKEKKYVEMLIRNQVDGVIAVTYNRGIFDSESQSLPVVAVDHYLSKDIPTVSSDNYSGGKQATELLILKDCKHIIHINGPLKLETPANLRRKAYENVMKKYGKQPVTYEISNTFDRNIQRETISKVFEENPEVDGIFASDDLLAALVVAEAQKRGKNIPRDLKIVGYDGTEASQTLLPGLTTVQQPIESIAQTAIDILLKEIEGEFSNIPREICLPVKLLEGQTT
>NC_014103.1|WP_013082487.1|1547821_1549063_+|MFS-transporter
MKSSKSLYWKLSAYFFFFFFTWSSSYSLFSIWLGQEIKLNGSATGLIFSVNAIFALCMQPLYGYISDRIGLKKHILFFISCLLVFVGPFYIFVYGPLLQYNVLIGAIIGGLYLGVAFLAGIGAIETYIEKVSRKYKFEYGKSRMWGSLGWAAATFFAGQLFNINPHINFWVASVSAIILVAIIFSVKVEMSSYEMEKAESVTLRDVGSLFLLKEFWFFMIYVVGVTCVYGVYDQQFPIYYASLFPTESIGNQVFGYLNSFQVFLEAGMMFAAPFIVNKIGAKNSLILAGFLMGFRIIGSGLVVGPIGISSMKLIHALELPIMLIAIFKYLAANFDTRLSSILYLVGFQFASQIGASVLSPIAGGLYDSVGFSRTYLIMGGMVLVFNVISMFTLLNSKKHRFIRKDVQENTQII
>NC_014103.1|WP_042452948.1|1549084_1550542_+|glycoside-hydrolase-family-32-protein
MNKIEQAQHSLNEAEKKVNHQYRLGYHIMAPANWINDPNGLVQYKGEYHVFYQHHPYDENWGPMHWGHVKSKDLVHWQHLPIALAPGDSFDKDGCFSGSAVGNEGELTLIYTGHNYIDKELDTFFQNQNIAVSKDGITFEKAEANPVIAEPPADSSHHFRDPKVWKHEGFWYMILGNSTKKQEGRVILYRSSNLQKWEYVGVLAKSDGDLGYMWECPDFFELDGKHVLMISPQGIEAKGDSYHNLFQTGYLVGEYNYGTNTFHHGSFTELDYGHDFYAVQTLLDDKGRRIAIGWMDMWEANMPTKEDGWCGALTLPRELTLREDKVLMNPVQELTSLRKTQYNMLTNKALSNSYVVEVNEDLLEIQAVFDLADCQASSVGIKIRGINNEETLMCYNLNEQKLLLDCTHSGKEDGVRKVALQAGETLALRIFLDRSSIEIFANEGQATMTSRIYPKESRLGIELFTEGGNVIVKELTYWNLKDIWG
>NC_014103.1|WP_013082489.1|1550815_1552276_+|YdiU-family-protein
MTNQKETGWNLRNSYAELPNIFFTPLDPNPVSSPKIVKFNDSLAASLGLQKEQLQSPEGVSILAGNSFPKGAFPLAQAYGGHQFGHFNMLGDGRAMLIGEQVMPSGKKVDLQLKGSGRTPYSRGGDGRAALGPMLREYIISEAMHALGIPTTRSLAVVTTGEAIVREKELPGAILTRVASSHLRFGTFQFAAKWGTVENLQALADYALERHFPYIEKNEKKYLSLLQEVIKRHATLVAKWQLIGFIHGVMNTDNMTISGETIDYGPCAFMDTYDPETVFSSIDVQGRYAYQNQPGITGWNLARFAEALLPLLDQDIEKAVEIAQSAVTEFPKFYRENWLAGMQAKLGLFNEEKEDEALFQDLLTIMKTYKADYTNTFRALTAEKLENSDLFESKEFAQWHELWQKRLGRQQQSKTESQELMKNNNPAVIPRNHRVEEALDAAQKKDYSVMETLLEVISSPYESPGQPEYCTPSAPSNQPYQTYCGT

Crispr_ID: NC_014103_6

• CRISPR_ID: NC_014103_6
• CRISPR_location: 2071519-2071608
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014103_6

Consensus_repeat	Method
TCAAATGCAGCCGCCAAGCGGTTC	CRISPRCasFinder

spacers of NC_014103_6

>6.1|2071543|42|NC_014103|CRISPRCasFinder
ATCGAACGGCGGTCAAATACCGGGTGGTTCGTCCAATAATGG

CRISPR arrays and Neighbor proteins around NC_014103_6

CRISPR arrays

The CRISPR arrays of NC_014103_6

>merge|NC_014103|6|2071519-2071608|CRISPRCasFinder
TCAAATGCAGCCGCCAAGCGGTTCATCGAACGGCGGTCAAATACCGGGTGGTTCGTCCAATAATGGTCAAATGCAGCCGCCAAGCGGTTC

>NC_014103|6|4|2071519-2071608|CRISPRCasFinder
TCAAATGCAGCCGCCAAGCGGTTC	ATCGAACGGCGGTCAAATACCGGGTGGTTCGTCCAATAATGG
TCAAATGCAGCCGCCAAGCGGTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013082947.1|2073027_2073432_+|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NC_014103.1|WP_013082949.1|2074460_2075135_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_014103.1|WP_013056825.1|2077400_2077553_+|Fur-regulated-basic-protein-FbpA	unknown	unknown	gnl|CDD|315692
NC_014103.1|WP_013082942.1|2067467_2068340_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NC_014103.1|WP_013082953.1|2079813_2080680_+|sulfate-ABC-transporter-permease-subunit-CysW	unknown	unknown	gnl|CDD|226665
NC_014103.1|WP_013082950.1|2075136_2076516_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_014103.1|WP_013082938.1|2064560_2065091_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|226489
NC_014103.1|WP_013082940.1|2066137_2066542_+|CidA/LrgA-family-holin-like-protein	unknown	unknown	gnl|CDD|167253
NC_014103.1|WP_042452049.1|2062525_2062891_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082939.1|2065514_2065946_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_014103.1|WP_013082944.1|2069005_2069578_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NC_014103.1|WP_013082936.1|2061923_2062523_+|DUF3298-and-DUF4163-domain-containing-protein	unknown	unknown	gnl|CDD|378702
NC_014103.1|WP_013082943.1|2068460_2068937_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013082951.1|2077805_2078870_+|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224529
NC_014103.1|WP_013082952.1|2078964_2079801_+|sulfate-ABC-transporter-permease-subunit-CysT	unknown	unknown	gnl|CDD|131194
NC_014103.1|WP_013082946.1|2072069_2073035_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133030
NC_014103.1|WP_013082948.1|2073428_2074316_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl|CDD|224131
NC_014103.1|WP_013082941.1|2066511_2067204_+|LrgB-family-protein	unknown	unknown	gnl|CDD|224265
NC_014103.1|WP_013056824.1|2076888_2077053_+|YezD-family-protein	unknown	unknown	gnl|CDD|378371
NC_014103.1|WP_042453007.1|2062964_2064389_+|phospholipase-D-family-protein	unknown	unknown	gnl|CDD|197210

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013082947.1|2073027_2073432_+|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	5.70964e-22
NC_014103.1|WP_013082949.1|2074460_2075135_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.07284e-78
NC_014103.1|WP_013056825.1|2077400_2077553_+|Fur-regulated-basic-protein-FbpA	gnl|CDD|315692	pfam13076, Fur_reg_FbpA, Fur-regulated basic protein A. This family of proteins is regulated by the ferric uptake regulator protein Fur. This family does not regulate the lutABC operon encoding iron sulfur-containing enzymes necessary for growth on lactate.	9.42134e-08
NC_014103.1|WP_013082942.1|2067467_2068340_+|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	8.53522e-41
NC_014103.1|WP_013082950.1|2075136_2076516_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.34452e-61
NC_014103.1|WP_013082938.1|2064560_2065091_+|GNAT-family-N-acetyltransferase	gnl|CDD|226489	COG3981, COG3981, Predicted acetyltransferase [General function prediction only].	4.92863e-56
NC_014103.1|WP_013082953.1|2079813_2080680_+|sulfate-ABC-transporter-permease-subunit-CysW	gnl|CDD|226665	COG4208, CysW, ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism].	3.90234e-144
NC_014103.1|WP_013082940.1|2066137_2066542_+|CidA/LrgA-family-holin-like-protein	gnl|CDD|167253	PRK01658, PRK01658, CidA/LrgA family holin-like protein.	8.07581e-35
NC_014103.1|WP_013082944.1|2069005_2069578_-|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.32675e-41
NC_014103.1|WP_013082936.1|2061923_2062523_+|DUF3298-and-DUF4163-domain-containing-protein	gnl|CDD|378702	pfam11738, DUF3298, Protein of unknown function (DUF3298). This family of bacterial protein C-terminal regions is highly conserved but the function is not known. Several members are annotated as being endo-1,4-beta-xylanase-like, but this could not be confirmed, and the structure can be defined as a heat-shock cognate 70kd protein 44kd ATPase.	1.26182e-14
NC_014103.1|WP_013082939.1|2065514_2065946_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.30608e-17
NC_014103.1|WP_013082951.1|2077805_2078870_+|sulfate-ABC-transporter-substrate-binding-protein	gnl|CDD|224529	COG1613, Sbp, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	0
NC_014103.1|WP_013082952.1|2078964_2079801_+|sulfate-ABC-transporter-permease-subunit-CysT	gnl|CDD|131194	TIGR02139, permease_CysT, sulfate ABC transporter, permease protein CysT. This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions].	3.2288e-143
NC_014103.1|WP_013082946.1|2072069_2073035_+|glycosyltransferase-family-2-protein	gnl|CDD|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	1.17287e-97
NC_014103.1|WP_013082948.1|2073428_2074316_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl|CDD|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	1.51441e-160
NC_014103.1|WP_013082941.1|2066511_2067204_+|LrgB-family-protein	gnl|CDD|224265	COG1346, LrgB, Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane].	6.80824e-77
NC_014103.1|WP_013056824.1|2076888_2077053_+|YezD-family-protein	gnl|CDD|378371	pfam10055, DUF2292, Uncharacterized small protein (DUF2292). Members of this family of hypothetical bacterial proteins have no known function.	2.45935e-11
NC_014103.1|WP_042453007.1|2062964_2064389_+|phospholipase-D-family-protein	gnl|CDD|197210	cd09111, PLDc_ymdC_like_1, Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins. Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins. In Escherichia coli, there are two genes, f413 (ybhO) and o493 (ymdC), which are homologous to gene cls that encodes the Escherichia coli cardiolipin (CL) synthase. The prototype of this subfamily is an uncharacterized protein ymdC specified by the o493 (ymdC) gene. Although the functional characterization of ymdC and similar proteins remains unknown, members of this subfamily show high sequence homology to bacterial CL synthases, which catalyze the reversible phosphatidyl group transfer between two phosphatidylglycerol molecules to form CL and glycerol. Moreover, ymdC and its similar proteins contain two HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue) that characteriszes the phospholipase D (PLD) superfamily. The two motifs may be part of the active site and may be involved in phosphatidyl group transfer.	1.65231e-60

Protein sequences

>NC_014103.1|WP_013082944.1|2069005_2069578_-|GNAT-family-N-acetyltransferase
MIQVKDIYGNLPTLETERLRLRKVTKKDVRDMFEYASNEKVSRYVNWEKHRKLQDTKEFVSFVLKQYSNQSISPWAMEIKALKKCIGTIDFVTWNPTHRIAEIGYAISEEYWNKGFVTEAAEKVIAFGFEEMDLVRIQARCFVENAASEKVMKKIGMSYEGTIRKAMFIKGAHQDLKLYSILREEYTRNA
>NC_014103.1|WP_013082943.1|2068460_2068937_-|hypothetical-protein
MLEQAIQHLDLSAHGLWFPITVSLCLFILALVLFKRQLTWRDFYITFCVVGFVGWLCDVIITRVFNMIDLGDPKVTGLGDILSYTFIPPSLSILFLTYLTAKNKWVLSLLFCAGSLLIEYGMIKSGYMHLNGWFFIYSIVVYFLVYAFVLPWHMAFIK
>NC_014103.1|WP_013082942.1|2067467_2068340_+|STAS-domain-containing-protein
MKEELVYIGKKILEHKYSLSEKLAERLDSTHTLSIEVLKEKKILKWRVSIMEYFGRALFEEQEDVLKLVKEWALDTGKYAVEKNIPLEKALGILPIYRSVIWDVFTRELEEHQFAAITMLHVSERIDPLLDTVTCVFGQIYDEHNRYMMNLAYTSLEELSVPLVPVTKGIAIMPIIGEIDTHRSQVIMETCLKKGTSLQLSYLILDISGVVIIDTMVADNLFKIHRSLKLVGVEAIITGIRPEIAQTVVKLGIDFNQIKTEANLEAALLKIGFRRPEEHSRAHVSSRRIK
>NC_014103.1|WP_013082941.1|2066511_2067204_+|LrgB-family-protein
MQEFFIALFIIIATVALYLVMAKVYVRFSYPILIPVLTTTVFVILLLLAFHISYDEYMIGGKWINSLLGPAVVALAYPLYKQREMLVKYSIPIIGGVFVGLFAGMISGLVFAEVFGIDRSLILSIVPKSITTPVAIQIATGLGGVPSMTVVFVMIAGFSGVILGPLLLKWIRIKSSLGKGIALGSASHALGTSKAFEYGELTVSMSSVSMTLSAVLGSVFGPIVVWLFQV
>NC_014103.1|WP_013082940.1|2066137_2066542_+|CidA/LrgA-family-holin-like-protein
MKVIRIILQIAILYAFSMIGEAVHHILHLPIPGSIIGLILMLICLTCKIVPIKVIEDGASFLLSFLPLLFIPAMAGVMNYPSLLSSSGAILFLIIVLSTIITMAAAGAASQLLEKKANKRKEKQQCKNSLSRSL
>NC_014103.1|WP_013082939.1|2065514_2065946_-|MarR-family-transcriptional-regulator
MQEKNSIELIEYELTTFIRRAVYLDNSENKIGNLERSAYLLLRQLDEFGPTRVKELAEAFKLDISTLSRQAAALENKKLISRSSDPSDGRVSLFEITPRGKRMLQTDKQMRLERYHSMLKKWSSEEKELFGKLLMRMNDAFID
>NC_014103.1|WP_013082938.1|2064560_2065091_+|GNAT-family-N-acetyltransferase
METAVLMKPDVAYKKAYMSFYHEWKASGEKMIPWVIAKDPAYFEKMVQELLDAEKGIGLKKGYVPDSTYWLMHHEKVIGVVNIRHELSEILRNSGGHIGYGIRPSERQKGYAKLLLRLSLQKIKKLGVQRALVVCDDWNTASRRTILANGGIQDEDYIEEDGAVVQRFWIHTDKMA
>NC_014103.1|WP_042453007.1|2062964_2064389_+|phospholipase-D-family-protein
MIKIAVKGLLIILSLYILYVVITAVVLFYVPLKTGEETTSIKPARFFGHRESTDRVRLLEDGYEAGRVRIQMIQEAEKSIDIAYYSIGKGESTDLIMAALFKAADRGVHTRVLLDGIANGLRGNRRGVLYALASHPNIEVKYYEPLQLFKPWAWQNRMHDKIMIVDGELGIIGGRNIGDKYLAKKPPSDFVYDRDVFITNSKHKQDSVITQMQNYINELWAHPYTKKAFHHLTQYQVDQGKRMKALLLQQYDKAKQVGETFATPKIDWNASTVPTKRVSFIHNPIERFNKRPFMWKTFINLAEGANRSVLIQSPYVVPTNAMRKYIAMKKNPAVQWTLLTNSVTSTPNVLAFSGYISMRDKIMKTGVKLYEYQGPYSIHAKSVIYDQRLSAVGSFNLDSRSTFLNNESMVIIDSQEFAKKLTMAMENKIDKSILIANHKRWIQSPDIQKKEEPVMKRTFLYALAKVTRFFKEFI
>NC_014103.1|WP_042452049.1|2062525_2062891_-|hypothetical-protein
MIALRFVFLTHLFFLIHYLYSMLVHIIEKRMIVMEEYSFRFHITDSYPLQNENDKIEAVVRTKIKHADRGCLYEGYLRVHITNIGVFPVAKDIAEAIGVRSLRQQLAAELKRYVRPHRNFL
>NC_014103.1|WP_013082936.1|2061923_2062523_+|DUF3298-and-DUF4163-domain-containing-protein
MVTLPATVYSQQMVKKKLNVYYPVVHLTNQAVQHSMNSKILQRTNELIRQQGYGENPDTEETGYYELKTNERNVLSLTLVNFAYSGGAHGLTVVVPLTFNVLTGKTYQLKDLFKKDSNYVSILSKIVGEQIKERDIMVLGEYKGIKPDQDFYIADKSLVLFYQLYDLAPYVYGIPYFPISIYAIQDIIEDESPLGQMFG
>NC_014103.1|WP_013082946.1|2072069_2073035_+|glycosyltransferase-family-2-protein
MSSIVKYSIVVPVYNEEEVIHETYRRLTEVMHSTKEAYELLFVNDGSRDRTAEIIKEYSEQDPAVVLLDFARNFGHQIAITAGMDYARGEAVVVIDADLQDPPELILEMIEKWKQGFDVVYAKRTKRKGETYFKKQTAAMFYRILGAMTDIDIPLDTGDFRLLDRKVCNQMNSIQEKNRFVRGLVSWVGFKQIAVEYERDERLAGESKYPLKKMLKLSMDGITSFSYKPLKLASYAGVTLSGIGFIYLLVVLYLKLFTDSTITGWSSLIVIQLFFSGIILIILGMIGEYIGRIYDETKNRPLYIVREKYQLEPRKEVSLRD
>NC_014103.1|WP_013082947.1|2073027_2073432_+|GtrA-family-protein
MTNKWISFIKFALVGVLNTLIDFVVYALLTTIGVNYILAQWISYSAGILNSYVMNRKWTFERKEKSSKREVISFVIVNLITLSLTSFLLTVLYNKWGVALLLSKLLITIVSVGINFIGTKLFVFTTKKERGIHI
>NC_014103.1|WP_013082948.1|2073428_2074316_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MTIKKAVIPVGGLGTRFLPATKAQPKEMLPIVDKPAVQYIVEEAVKSGIESIIFITGRNKKSIEDHFDKSTELEQMLEEKHKFQMLKEVQTISSMASIHYIRQKEPLGLGHAILCAEQFIGDEPFAVLLGDDIMTSEEPALKQIIQAYETTNQSVIGVQKVDVEEVSKYGIIQPKNKSGSLHEVNDLIEKPSIEQAPSTIAVMGRYILNPSIFSYLKTIERGVGNELQLTDALGVVCEKERLFALELEGQRFDIGDKVGYMKAMVEVALKRRDLRQTFLSYLEGIVEKERANNFS
>NC_014103.1|WP_013082949.1|2074460_2075135_+|response-regulator-transcription-factor
MIQILVADDDQHIRELISLYLENQGFKIIKAADGEEAWAKMEEFRIDLAVVDIMMPFKDGWELTKEIKEYFDIPVLMVTARGESHDKLKGFDIGTDDYVVKPFDPQEMVARVKALLRRYRVEANNVIYMGNIKLDRTKLEMSAGETSEQLPLKEFELLFTLVSSPGKIFTRDQLIQLIWGYDYEGEERTVDVHIKRLRERLNHMKNVGMEIKTIRGLGYRAEGC
>NC_014103.1|WP_013082950.1|2075136_2076516_+|HAMP-domain-containing-histidine-kinase
MKSIYVKLVLSFIITILLSVVITVVVTTVLSKQKLEMRLGQDMVKMGEDFIDLYGAEDSDKAARFLSNSSFIHFSFIIIDDQHEEKVLGQPGPPIPITPKEVDQVLDGKRYSNLNEEKDDRPQPNVVGLPFKENGRSYALFIQSHPQRQFSVIQDVQNIQLITILLVGIVLFAYVSMIIIKPIKRLSTAMKVVGQGEYNVQVEHAANDEIGLLTKNFNQMTKELNKIETMRQEFIASVSHEIQSPLTSIRGFSAALKDDIVSEDKKIQYLTIIEKESTRLSQLSSNLLKLASLDSEHQTLMLQQYRLDEQIRHVVMALEPQWTKKNIEIDLDLSNVQIEADKDLLEQVWLNLVTNAIKYTPENGFVKISIHQKNEEIDVKIKDNGIGIAEEDQKYIFESFYKVDKSRTLKGSGLGLAITKKIVRLHEGAVRVESKKEQGSIFSVTLPIQKNRAKKDSSV
>NC_014103.1|WP_013056824.1|2076888_2077053_+|YezD-family-protein
MASITQEKLDYIVKLLTEINYGSVLITLHDGQITQVDSTEKNRFLAKSKVASHK
>NC_014103.1|WP_013056825.1|2077400_2077553_+|Fur-regulated-basic-protein-FbpA
MENLLRAAVRQRKQYLIEELLKKGIYKKENHHLFELTLSDLEKEYQARSK
>NC_014103.1|WP_013082951.1|2077805_2078870_+|sulfate-ABC-transporter-substrate-binding-protein
MKKKAVQFLMVLTALLVVLAGCGNGKSTETAGKDSSASKNDSKKPVELLNVSYDPTRELYQEFNKSFASYWKGKTGQDVTIKQSHGGSGKQGRAVIDGLEADVVTLALAYDIDEIAQTRQLLNKDWEKELAHNSTPYTSTIVFLVRKGNPKGIKDWDDLTKKGTSVITPNPKTSGGARWNYLAAWAYAKNKYNGDNKKIEDFMGKLYGNVEVLDSGARGATTTFVERGIGDVLIAWENEAYLSLNELGKDKFEIVTPSLSILAEPPVAVVDKVAEKKGTTKVAKAYLKYLYTEKGQEIAAENYYRPRNEKVLEKHKDQFPSLNLVTIKDFGGWKKAQETHFNDGGTFDQIYQPK
>NC_014103.1|WP_013082952.1|2078964_2079801_+|sulfate-ABC-transporter-permease-subunit-CysT
MSVLQRQKKKKSILPGFGLSLGFTMFYASILVLFPLAMIFLNTASMGWSDFIKTVTDSRVVASYKLSFGAAFAAGIINVIFGTIIAWVLVRYHFPGKRFIDGLVDLPFALPTAVAGIALTTLYVPKGWIGQLFTFKIAFTPIGIIIALTFIGLPFVVRMVQPVLQNFNAEIEEASASLGASRMQTFRKVIFPELVPAILTGFSLSFARALGEYGSVVFIAGNMPMKTEITPLIIMTKLEQYDYAGATAIASVMLVVSFFLLLLINIIQWWTNRKFVHS
>NC_014103.1|WP_013082953.1|2079813_2080680_+|sulfate-ABC-transporter-permease-subunit-CysW
MAGHVPMQHAKTTVKLNHSSLKEPKVVQWLLTFIALAFLVLFLVLPLITIFMTAFQKGLETYLAAITNPDALAAIKLTLIVVLITVPLNAVFGMVAAWLITKFDFKGKNILITLIDLPFAVSPVIAGLVFILLFGAQGLFGEWLFNQDIKIVFAIPGIILATLFVTLPFVAKELIPLMQAQGSAEEEASLTLGASGFKTFFLVTLPNIKWGLLYGIILCNARAIGEFGAVSVVSGHIRGMTNTMPLHIEILYNEYQFAAAFAVASLMSILAIFTLIIKNIIEWKVKHI

Crispr_ID: NC_014103_7

• CRISPR_ID: NC_014103_7
• CRISPR_location: 2263605-2263696
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NC_014103_7

Consensus_repeat	Method
GGGTAAAATGGACGAGGGCGAGG	CRISPRCasFinder

spacers of NC_014103_7

>7.1|2263628|46|NC_014103|CRISPRCasFinder
GTAAAAGTAAGGGGGGTGGTAATAAATGGGGCGAGGATAAGGGTAA

CRISPR arrays and Neighbor proteins around NC_014103_7

CRISPR arrays

The CRISPR arrays of NC_014103_7

>merge|NC_014103|7|2263605-2263696|CRISPRCasFinder
GGGTAAAATGGACGAGGGCGAGGGTAAAAGTAAGGGGGGTGGTAATAAATGGGGCGAGGATAAGGGTAAGGATAAAATGGACGAGGGCGAGG

>NC_014103|7|5|2263605-2263696|CRISPRCasFinder
GGGTAAAATGGACGAGGGCGAGG	GTAAAAGTAAGGGGGGTGGTAATAAATGGGGCGAGGATAAGGGTAA
GGATAAAATGGACGAGGGCGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013083108.1|2258583_2258829_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083120.1|2269091_2270585_+|sodium:solute-symporter	unknown	unknown	gnl|CDD|223664
NC_014103.1|WP_016764069.1|2261643_2261796_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083106.1|2257441_2257933_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083118.1|2267753_2268608_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NC_014103.1|WP_013083122.1|2271215_2271809_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|236397
NC_014103.1|WP_013083112.1|2262674_2263568_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|276809
NC_014103.1|WP_013083110.1|2260711_2260969_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083119.1|2268894_2269092_+|DUF3311-domain-containing-protein	unknown	unknown	gnl|CDD|371707
NC_014103.1|WP_013083113.1|2263964_2264477_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350305
NC_014103.1|WP_013083117.1|2267012_2267519_-|hypothetical-protein	unknown	unknown	gnl|CDD|372729
NC_014103.1|WP_013083107.1|2257922_2258213_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_157862158.1|2259564_2259732_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_042452107.1|2261836_2262526_+|hypothetical-protein	unknown	unknown	gnl|CDD|173412
NC_014103.1|WP_013083109.1|2259066_2259456_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083115.1|2265076_2265637_+|hypothetical-protein	unknown	unknown	gnl|CDD|182235
NC_014103.1|WP_013057013.1|2270811_2270979_+|Fur-regulated-basic-protein-FbpA	unknown	unknown	gnl|CDD|315692
NC_014103.1|WP_013083116.1|2265884_2266862_+|ring-cleaving-dioxygenase	unknown	unknown	gnl|CDD|319935
NC_014103.1|WP_013083114.1|2264484_2264841_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_016764066.1|2259823_2260060_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_014103.1|WP_013083122.1|2271215_2271809_-|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	3.5e-34	113.0	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013083113.1|2263964_2264477_-|PIN-domain-containing-protein	gnl|CDD|350305	cd18738, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	8.72592e-20
NC_014103.1|WP_013083117.1|2267012_2267519_-|hypothetical-protein	gnl|CDD|372729	pfam13798, PCYCGC, Protein of unknown function with PCYCGC motif. This domain contains a PCYCGC motif and four other conserved cysteines. Its function is unknown.	2.72643e-74
NC_014103.1|WP_013083120.1|2269091_2270585_+|sodium:solute-symporter	gnl|CDD|223664	COG0591, PutP, Na+/proline symporter [Amino acid transport and metabolism / General function prediction only].	5.99219e-68
NC_014103.1|WP_013083112.1|2262674_2263568_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	6.02594e-07
NC_014103.1|WP_013083118.1|2267753_2268608_+|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	4.81317e-35
NC_014103.1|WP_042452107.1|2261836_2262526_+|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	0.000121943
NC_014103.1|WP_013083122.1|2271215_2271809_-|DNA-polymerase-III-subunit-epsilon	gnl|CDD|236397	PRK09182, PRK09182, DNA polymerase III subunit epsilon; Validated.	5.73016e-58
NC_014103.1|WP_013083115.1|2265076_2265637_+|hypothetical-protein	gnl|CDD|182235	PRK10092, PRK10092, maltose O-acetyltransferase; Provisional.	1.58056e-101
NC_014103.1|WP_013083116.1|2265884_2266862_+|ring-cleaving-dioxygenase	gnl|CDD|319935	cd08347, PcpA_C_like, C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The C-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	1.57879e-63
NC_014103.1|WP_013057013.1|2270811_2270979_+|Fur-regulated-basic-protein-FbpA	gnl|CDD|315692	pfam13076, Fur_reg_FbpA, Fur-regulated basic protein A. This family of proteins is regulated by the ferric uptake regulator protein Fur. This family does not regulate the lutABC operon encoding iron sulfur-containing enzymes necessary for growth on lactate.	0.00793209
NC_014103.1|WP_013083119.1|2268894_2269092_+|DUF3311-domain-containing-protein	gnl|CDD|371707	pfam11755, DUF3311, Protein of unknown function (DUF3311). This is a family of short bacterial proteins of unknown function.	2.53955e-11

Protein sequences

>NC_014103.1|WP_013083112.1|2262674_2263568_+|helix-turn-helix-transcriptional-regulator
MNDKKQVGQLIQDLRKIAEMTTVELSEGICTEEELHRFEQGEIHASSEVLYHLSKRLGVPMNYFFEAGELTPNDYSKEIKSTIRHYIRKRDYETVLHMVNKEKDNPMFQDPFHAQFFLWHEAICDYYIGNKFEQALRKLEKAIAFTRTSEQFYSEKEIAILNSIAIIYEEEGHLKKAFSTFMEGLQHIALLPKLKDPLVKIRILYGLSRALLQMERYEKSVKYAQAGLELCIQHETLYLLGELHYQIGEALCQLGELKEGIAYLEKAITVFEIEQNEAFVTIIQEEMSKYQETKKKS
>NC_014103.1|WP_042452107.1|2261836_2262526_+|hypothetical-protein
MKKLLVGSILLSLSLTMGACHQGEEKNAETSKKETAVKPEKKTNEIELNKKSESIQIQDEQKDLRAYATKVEEERKAKELAEQKAKEEAEAKQQVEIAEQQRQQKIAEEQRVSAQQAEQKKEAESPVSQETIDNYEANQAETWAEEAEIEEELNKEEEERLAKEQAEQEAYEAQIIAEQDANFSDEAKEQIQKEIDEEGYSQTSYYCDQVMTAVQRGDMTKEEAGGCLK
>NC_014103.1|WP_016764069.1|2261643_2261796_+|hypothetical-protein
MNEQLKPEEISIEVKLELLKICNNVMNNIVTPKELIKDLEKLVSQISLSV
>NC_014103.1|WP_013083110.1|2260711_2260969_+|hypothetical-protein
MNYEQKDYYISAKENEYYKVLNVVDHMLEEAKSNDRYPVWGEKLRNELKESAGNNLTPWHFNMIISTLLDYVPEEVKNKSNAKSL
>NC_014103.1|WP_016764066.1|2259823_2260060_+|hypothetical-protein
MKIQFDFKVLNVVEENGVKSYIVQCSSENFRRVIKAQYDGSVYIPDYHQQLWDIQSHERTVLDIGLASFIIKNENRTV
>NC_014103.1|WP_157862158.1|2259564_2259732_+|hypothetical-protein
MNQVLFEQLLEGNIEYEDVPEDTDIELTDEERHEMRLWLVGVYGFSYGAAKSYID
>NC_014103.1|WP_013083109.1|2259066_2259456_+|hypothetical-protein
MGKSKNWMDAYVSKVSGKHFELLSVQSVIDSFIDMLNVKLNENQQPEVEFIKEENKISFPDCSVFLKVQGSILSLSKVLKSNNQVAGGIKIFDTGLTYQLKTGSKLIEEVETIPEALDRALSYLLVELR
>NC_014103.1|WP_013083108.1|2258583_2258829_-|hypothetical-protein
MVAKINSLTIGNISGGTFIFGNVNQVCPVTSTESNSQTGLGSNASPNSSSVTGSQNTSSQQSPSSTPTQTPTLGSGNTNTL
>NC_014103.1|WP_013083107.1|2257922_2258213_-|hypothetical-protein
MSRFDIETLKKIRDDLQEIHSTAISNYHDYPELMDTIDHLARVANMFANDKIENLVNNNLRADPQGYIVSKLSSASSRMKNYQKGIGKREVGSYEN
>NC_014103.1|WP_013083106.1|2257441_2257933_-|hypothetical-protein
MKIEYTGWRFYDDYTEIYGRNYLIHHAGSMLVPVSRIKGLTHDNVLSVEKLNRLLKSIKNHGYVTTSSSHMDINLTLFPNGDFCVSNGGNHRPYLAKKLGITIIRAVVDVCIPLNLLTDEQIQYFESIGSYDLPNSPELKDVAYALELMPSQQLAKQTIIHIQ
>NC_014103.1|WP_013083113.1|2263964_2264477_-|PIN-domain-containing-protein
MLDEKVIIDTNIWASHALNYPEVVEYINELISNNAEFLMPTVVEMELLSHWEVETNPQVKAVKNHYIYDMTDKIVDVTSEIAQLAAQIRRKAKIESNKKIKGPDAMIAASAFIHNAKLISNNNKDFAWITFNFSYRGQPLSYVNPIKDTIAYASFIKSFEHPTLPDADNL
>NC_014103.1|WP_013083114.1|2264484_2264841_-|hypothetical-protein
MKAQRLVDDQKGTYSKEVQKHFNLKINGKIYTQPSPQSPSSPPMQKKNLKYKPQNKVLRTYDKKDKTLNDTQEKLIKSAKTRLTKYEKLLLSNQLSESAVLYSPSGLEELVRMASREE
>NC_014103.1|WP_013083115.1|2265076_2265637_+|hypothetical-protein
MKTEKQKMLDGELYLSADPQLIKERENARRLTRLYNQTTEREEERRTNLLKELFGSTGNSLCIEPTFRCDYGSNIHVGENFYANFDCVLLDVCEIRIGDNCFLAPGVHIYTATHPLHALERISGAEFGKRVEIGNNVWIGGRAVINPGVKIGNNAVIASGAVVTKNVPDNMVIGGNPAVIIKHIEN
>NC_014103.1|WP_013083116.1|2265884_2266862_+|ring-cleaving-dioxygenase
MNHLKGIHHVTAITSSAEKNYEFFTYVLGMRLVKKTVNQDDIQTYHLFFADDKGSAGTDMTFFDFPGIPKGFHGTNEISKTSFRVPNDAALEYWVKRFDRLEVNHTGIQELFGKKTLSFVDFDDQQYQLISDEGNQGVESGTPWQKGPVPLQYAITGLGPIFIRIAEFNYFKEMMEKVLLFKEIAQEGDLHLFEVGEGGNGAQVVVEHNEKLPQAQQGFGTVHHVAFRVENRQALEEWINRMPSFGFHTSGYVNRHFFESLYARVAPQILFEFATDGPGFMGDEPYETLGEKLSLPPFLEPKRAEIEKLVRPIDTVRSTKEFVKE
>NC_014103.1|WP_013083117.1|2267012_2267519_-|hypothetical-protein
MKKSIILLGILATSIGLSACSNNTTTSSATNSSAHSGHEHHKAAVADIREETPGADVLPQFLKNQPKDMKLVYLSVAKNRELLEKIPCYCGCGMEANHKNSYDCFIFKNKRNGAVVWDDHGTKCGLCIEIAAKAMLDYNRGKSIKDIRKDIDEKYKEGYAQPTPTPSL
>NC_014103.1|WP_013083118.1|2267753_2268608_+|STAS-domain-containing-protein
MSEQNQRLFEYILENSASISEEWLRQRSNIKGSIYSKDADASVEKKLREQHLYTIETIASGFLDDQKIFKQRMVKWTTEVVNSRIKFDTPIYEVVEALSKTRKIIWTYVKTYSLIHSSITKEDILSWSEVYHTTFDKLINEFSEQYYKITRQKISLQQELIDETSFPVIPIVDHIAVLPLVGLIDEIKGDSIIEVVPKKCAEKHIRHLVIDLSGVNYVDTYVAHKFFDLINILQLLGIHSIMSGVSPDMAQTAVNVGISFNKIETFGHLKQALSSLGVKKKEKV
>NC_014103.1|WP_013083119.1|2268894_2269092_+|DUF3311-domain-containing-protein
MKIIYLLCLLPFVGILGLLPFVNKVTPFILGMPFFLFWIVMWVILTSFIMGIVYKLDPAVKGGDK
>NC_014103.1|WP_013083120.1|2269091_2270585_+|sodium:solute-symporter
MNTALIIIFVFLLLAIYLGIRATRGKKMDLEQWSVGGRGFGTVFVFFLMAGEIYTTFTFLGGSAWAYGKGGPAFYILAYISLAYVLGYWIGPQIWRYAKQHKLMSQPDFFVSKYNSPFLGIVVSCAGVLAIVPYIILQFKGLGIIVSEASYGSISSTAAIWIGAISLTVYLMISGIHGSAWTAIVKDIMIFIVVLFLGIYMPIHYYGGLQPMFEAVHQANPTFLTLPKTGLSISWFISTVMLTVLGFYMWPHTFNATYSAENENVFRKNSIISPIYTLMLLFVFFVGFTALMQVPGLQGAEADLSLLRLSIQTFDPWIVGFIGAAGLLTALVPGSMLLMAASTSLSKNVYGVLVPSATGKQISILAKCFVPVIALVSVYFTLHGGNTIVTLLLMGYSIVTQLFPAFIFSLMKNNIVTKYGACAGIVAGIASVMYITITETTLGTLFPALPQIIKDTNVGVISLFINLVVLMVVSLATKKIAAQPHFESGAVDEKQIL
>NC_014103.1|WP_013057013.1|2270811_2270979_+|Fur-regulated-basic-protein-FbpA
MTSEKAFEQKKDLLMNQIIESGYFKAEDGRHLYELNLSELEQTHHDLQNQKIREV
>NC_014103.1|WP_013083122.1|2271215_2271809_-|DNA-polymerase-III-subunit-epsilon
MSTEQVKLAAVLDVETTGLSAQTCDIIELAIAVVSYDSSTGEIIDIVEEYEEFNMPSTPIFPYITNLTGITNEMVKNKTLDDKKVESLLTSVSAIIAHNASFDRSFLLKRYPSLSNQKWHCSMRAVKWKEYGFPNKKLTTLLDHHNIEREHAHRAMDDVKGTIDLLRQQNPSGEPYFSEVLKKAMSKPKKTAASTRF

Crispr_ID: NC_014103_9

• CRISPR_ID: NC_014103_9
• CRISPR_location: 2858051-2858135
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014103_9

Consensus_repeat	Method
CTTTTGCCGTTTTTGGCGTACTA	CRISPRCasFinder

spacers of NC_014103_9

>9.1|2858074|38|NC_014103|CRISPRCasFinder
CTCTTCACTTTTGCTATTTTTGGCGTACTATACTCAGC

CRISPR arrays and Neighbor proteins around NC_014103_9

CRISPR arrays

The CRISPR arrays of NC_014103_9

>merge|NC_014103|9|2858051-2858135|CRISPRCasFinder
CTTTTGCTGTTTTTAGCGTACTACTCTTCACTTTTGCTATTTTTGGCGTACTATACTCAGCCTTTTGCCGTTTTTGGCGTACTAA

>NC_014103|9|7|2858051-2858135|CRISPRCasFinder
CTTTTGCTGTTTTTAGCGTACTA	CTCTTCACTTTTGCTATTTTTGGCGTACTATACTCAGC
CTTTTGCCGTTTTTGGCGTACTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013083667.1|2855968_2857432_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083669.1|2858401_2859424_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein	unknown	unknown	gnl|CDD|349995
NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein	unknown	unknown	gnl|CDD|226728
NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase	unknown	unknown	gnl|CDD|177683
NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein	unknown	unknown	gnl|CDD|372730
NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319825
NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_014103.1|WP_013083672.1|2863442_2863934_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083659.1|2847921_2848482_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase	unknown	unknown	gnl|CDD|376723
NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase	unknown	unknown	gnl|CDD|377080
NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase	unknown	unknown	gnl|CDD|377591
NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein	unknown	unknown	gnl|CDD|214615
NC_014103.1|WP_155276297.1|2849393_2849537_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein	unknown	unknown	gnl|CDD|224203
NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein	gnl|CDD|349995	cd18551, ABC_6TM_LmrA_like, Six-transmembrane helical domain of the multidrug resistance ABC transporter LmrA and similar proteins. This group represents the six-transmembrane helical domain of the multidrug resistance ABC transporter LmrA from Lactococcus lactis and similar proteins. This transmembrane (TM) subunit possesses the ATP-binding cassette (ABC) exporter fold, which is characterized by 6 TM helices per subunit (domain), or a total of 12 TM helices for the complete transporter. The ABC exporters are found in both prokaryotes and eukaryotes, where they mediate the cellular secretion of toxic compounds, a various type of lipids and polypeptides. ABC transporters typically consist of two transmembrane domains (TMDs) and two nucleotide-binding domains (NBDs). The sequences and structures of the TMDs are quite varied between the different type of transporters, suggesting significant structural diversity of the translocated substrates, while NBDs are conserved among all ABC transporters. The two NBDs together bind and hydrolyze ATP, thereby providing the driving force for transport, while the TMDs participate in substrate recognition and translocation across the lipid membrane by alternating between inward- and outward-facing conformations. Moreover, some ABC genes are organized as half-transporters, which must form either homodimers or heterodimers to form a functional transporter. The ABC exporters play a role in multidrug resistance to antibiotics and anticancer agents, and mutations in these proteins have been shown to cause severe human diseases such as cystic fibrosis.	0.00168085
NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.0693e-94
NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.91536e-58
NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein	gnl|CDD|226728	COG4278, COG4278, Uncharacterized conserved protein [Function unknown].	3.83906e-09
NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase	gnl|CDD|177683	PLN00052, PLN00052, prolyl 4-hydroxylase; Provisional.	1.23178e-41
NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein	gnl|CDD|372730	pfam13799, DUF4183, Domain of unknown function (DUF4183). This domain of unknown function contains a highly conserved ING motif.	1.45024e-05
NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase	gnl|CDD|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.16125e-44
NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.32118e-12
NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase	gnl|CDD|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase	gnl|CDD|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	5.97841e-145
NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase	gnl|CDD|377591	pfam06039, Mqo, Malate:quinone oxidoreductase (Mqo). This family consists of several bacterial Malate:quinone oxidoreductase (Mqo) proteins (EC:1.1.99.16). Mqo takes part in the citric acid cycle. It oxidizes L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial acceptors or, via the electron transfer chain, to oxygen. NAD is not an acceptor and the natural direct acceptor for the enzyme is most likely a quinone. The enzyme is therefore called malate:quinone oxidoreductase, abbreviated to Mqo. Mqo is a peripheral membrane protein and can be released from the membrane by addition of chelators.	0
NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	1.902e-24
NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein	gnl|CDD|214615	smart00318, SNc, Staphylococcal nuclease homologues.	6.16774e-38
NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein	gnl|CDD|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	7.84883e-69
NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.55281e-74

Protein sequences

>NC_014103.1|WP_013083667.1|2855968_2857432_+|hypothetical-protein
MNEPSNFSPYLIKQISDAIDDNIKAKCIDFLYDSHSFFSNEKDFIEDYILNILQDTFVLENKLINPKEIRNPAYKRRQSNKKNWLQTLKKDIKAEKPNPIFEDIELAKKVMDKKVDTEHLKKLFGVEKPEDILKIKLKEVEAWAKSKKTNITDFPYLDSKMNYQIEKAFHTDFTFLIAEIILEKYNGNLSNWIDKRLNSWVEAPIFSNESHSLKTNMEVKTNSQEVVLYNDYKVDEEYFIRTIIPVNDNQTVLSKRNMVLDPKDSQIIQFALSQRDEMFYKEKTVTLDLADIVKEIYNSKGVKNYEAVEARIMKIARYHVEGVAKKKNSRDTKFAINFFQKAVIETDEVTGRRYATIVFSDDTHQGFLNQQFVQIYSDVIKKFKDNSLSSLLLYAFQKERLDCYLQEKSYTHFYPYQYFASKVRFRSKKIDVNLKLINESLAEFVSNQVLIQSYQQKLQGFEISFIPLQNYEIQDYFGGEHRETLEG
>NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase
MLLKPKAIFLDMDGTILNRSNKVSIQTKEIIDELRKQGIFVFIATGRAFDEIEELVPEGFQVDGFITSNGMAGYVGKESVFQHSLSLQLVETIIEKARANKVYYELFPYGTPRVTLKQDQSYVENEIREPKPDSVEINEWLSRKQAIKEEIDWKDSVEGSEFSKFYFFARTHEHIDKWKEELEELKKEIDFTTSTSSKHNVEVMVANVNKATGIQQMLKHFNLPEQDILAIGDSNNDLPMFQFASYAVAMKNAPDHIKEIVDDVTEFNCDENGVSHYLSKFLLQKSTRSNPVL
>NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase
MNKRKIVYIVSDSVGETAELMVKAVLTQFSGEDIEIQNTSYVEDEGNIDNIIAEARCNEAIIAYTIVIPPLKQYLDQKAQEEGIVAIDLMTPLMSAFSQTFNKEPNLQPRLTRKLDDNYFRRVEAVEFAVKYDDGQDFRGIKRADLVLIGVSRTSKTPLSMYLAHKSLKVANIPLVPEVTPPDELFTIPKNKCIGLVITPDKLNEIRKERLKNLGLASQANYANVDRILEELDYAEKIMKRIGCPIVNVSGKAVEETAEVILSMLKKDKMKGYV
>NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase
MSNVYKKTDVILIGAGVMSATLGSLLKELAPEWEIKVFEKLADAGEESSNEWNNAGTGHAALCELNYTSEQADGSIDITKAVRINEQFQLSRQFWSYLVSSNLIHHPQEFIMPIPHMSFVQGEKNVSFLKKRFEALSNNPLFQGMEYSDRPEKLKEWMPLVMKGRTSTEASAATKIDSGTDVNFGALTRMLFTHLKSKRVEINYNHSVENLTRTADGSWEVKVHDIHTGKQEYHTANFVFIGGGGGSLSLLQKTGIPESKHIGGFPVSGLFMVCNNPEVVAQHHGKVYGKAKVGAPPMSVPHLDTRYIDRKKTLLFGPFAGFSPKFLKTGSNLDLINSVKPNNILTMLAAGVKEMGLTKYLIQQVLLSDEKRMEELREFIPNAKSEDWDIVVAGQRVQVIKDTEAGGKGTLQFGTEVVSSADGSVAALLGASPGASTAVHVMLEVLEKCFPQHMKKWESKIKEMIPSYGLSLVENPALFNEIHASTAQTLDLSKKELVYR
>NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase
MILTNTSLLTKEQTIFNHSGNKIKLEDREINIVARFEEPLVLVLGNVLSNEECDELIRLSKDKMQRSKIGAAREVNSIRTSSGMFFDESENELVHQIERRLSKIMGPSIEYAEGLQILKYLPDQEYKAHHDYFTSASKASKNNRISTLVMYLNDVEEGGETYFPKLGLSVSPTKGMAVYFEYFYSDAELNDRTLHGGAPVIKGEKWVATQWMRKQKIRS
>NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein
MKEIKAIICTMLAMFMLLLTGCSDEQASHSSTSSTDTKQAVQVEGSSDQEEDRSPSKANREDVVGEAATVERVVDGDTLKVKMLNGKRDRVRLLLVDTPETKHPKLGVQPFGPEASAYTKKRLEGQEITLEFDVQERDQYGRLLAYVWIDNELYNEELLAKGLARVAVFPPNTKYVDEFKKIQEQARKSEKGIWSIENYAQEKGYNTDAVKNQSSSKQKDTQSAKSCEGKIKGNQNSKIYHAPTGAHYNQTMNNVIWFCTEKDAQEAGYKKAKN
>NC_014103.1|WP_155276297.1|2849393_2849537_+|hypothetical-protein
MKKHRQQKDTTVSGWEVLAEILLQVPQLLIWPLRLLIRIGRSLLDGI
>NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase
MKIRKARKEDASAVTELLYDMLGSIARSHTAATTNEEALLRLKAFILSEKNRYSYHHITVAEVEEKVVGLMLCYEGSMLQTLYEPVKRFVRAKLNNPAWEIDIETEHGDYYIDSLCVDEAYRGKGIGTALLNVAKQEAKKHKMFLSLNVEYNNVEAKKLYQRIGFQEHKTIFIDKKPFFYMKTA
>NC_014103.1|WP_013083659.1|2847921_2848482_-|hypothetical-protein
MNIRDLPFNMSYRFNEQLREVPVNPHQMKQGIIYLKKRALEEEDECAAAKTYGHIGVYERILGELTSSERHLLLAIYLYDRHADTIGEFLNTIRLGHTYHWQEHWDKANETFQLLIEQLKADEDLHIYEDFVYQHYGKCLLDQRVVSRAHHYFQRALEIRLKKGDKELIESTNSCIRLCLNKLKHS
>NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein
MSKTVKDVIFLLIGSFVFSLAVNMFVIPIGLGEGGVTGISIILYYTTHLSTGSTNFILNGILLIVGYKFLEKKTIVYTMITIIATSIFLHVTEGWGLHLHEEHIGMVFAGVLLGVGIGMILRVGGTTAGSAIIARILNKFLNWKVSHALLIVDLLVVLASYFIIGIEKLLFTIVMLYIITKVIDFVIEGFDAKKAVTVILSNKNEVADQITEQLDRGVTILNGRGNYTKESKEILYVVINKQELIKLKKLIKKIDDEAFVIVHDVRDVIGKGFLSA
>NC_014103.1|WP_013083669.1|2858401_2859424_+|hypothetical-protein
MIKKEFAKIGKQIIRQLSSTVEKYKDIEDHMDLDAHGNPTIKTVAEHHRLSKSQISQLIFYHFLHVDERGIICDVSEKEIAAALNCTVRTVRNNNVVLAETELISYSRSGKGINICIVPYPQYFEEHGFGFMELEYTRFEELILIENVNALRLELRKELVYDNDTIKRQFNPAENTSKISFNDYKIFTPKYTHYKGMMQKIAETQTSAFKTVVQGSTIFFVLKDGAKNGKMSKQEKKDQYDAAIRRTIEETFVKLSGHSTDSTGIVMSSFQNEDIADLVQLSFEYGIERVKSALYSLIEQAFFSHDAQVVENYGGKIRTLIRKELSKNLQDQVPAELTAS
>NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel
MKDIQWVQQTLFNTGKWIDISEVIIKIILIFIIAQIVIRFARSVINKIFDFRFKTKLLRYNERKEITLKKLCLSIVMYVVYFIVLITSLEAIGINMKALLAGISVAGFITGLGAQNLIKDILNGFFILFEDQFSVGDHVSINDTKGTVEEIGLRTTKIRGVDGEFYFFANSNITKVANYTLGEIPEVHKPEQIKN
>NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase
MNILWDFDGTIFDTYPTIVKAFKELLTDQTISEDDILKQMKISSDIAIKHFDIEKSLFDKHFHVLEQKINPKDKPAFPHVEDVLSFADTNVIVTHKSRQSTLDILAFFNMEHYFTEIITKDDGYKRKPDSGAYAYLHDKYQLDLVIGDRELDLKPARELGIKTCAFQNDDIEADYHLTSYDQFFICSGLCTSGISPSV
>NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein
MISAIIVGAVILLALIIKGIGKPRGFRLYKEELPDELGIHGGNGFEDIVHSLEDSLPKAYVQQVKQRMQGRNTKDDEVEWTFFEIKRYFLLNAVIKDVPMFSAKVDEVWHEMIMFTVDYERFTDRFFSRFLHHQPNLETTPSPQPDKRAFFDWVYAHLFNITGNSRLLWGKFFQHPLDKSTLQDFQRLSEDELLDRYFLRNGKWEKQQRALIQTLKEEINAAQKRKKAGGSTYFKKTAKKGNVSNELLLQGFVFYSLYKATNFSSHMNELLLYKKTMYAGDAASYSGYSCSSPGEDNRHHHQHDGGHYHHDSGSSCSSSNCSSSSCSSSSCGSGCSSS
>NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein
MSLSAKKILLLVLVVICLVLVVMQFINRSAEPTSEQAQETLSKLPEQETVKEKAKGDEEAHKYRVYYITIEKIENGTYSGTTKEGTGIKFSDKNLNEPIPSNLKKGDIVKAYFDLEYSTKGLVKVEKVDEMPDDDESSS
>NC_014103.1|WP_013083672.1|2863442_2863934_+|hypothetical-protein
MMFALIVVVGIVALGVASFYVIKRPQGAVDPEDRKPLVSVNGHVKFAEGINQISISKIDMYDQRLVINQVAIIPFNRIQRAEFSKVVKNEKGLHGAPVQRYFGELTIHFTDKNGQETYIRCETPKKNQFHLIYQYDLMKRQLNKRLGLEDLQPYLTLQEPYEL
>NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein
MFPKKVRIFEYYTVAGGSKRIFTDQDALKEYDTQHILDSESYSYSNLFINGV
>NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase
MEQFERNIEKYAELAVKVGVNIQKGQILNINADISSADFVREIAKKAYEAGAKSVDVDWHDDPLVRLKYEKADESVFNEFPGWKAQAREELVKNGGAVLSVISSGPDLLKGVDGKRIAAFQKVSGKAMKKFREAIQSDKISWSIVAVPSKDWAAKVFPDVPEEQQQEKLWEAIFKSVRVDQEDPVAAWEEHNASLHTKVDILNEKRFAKLHYKAPGTDLTIELPDKHIWVGAGSVNEDGNSFMANMPTEEVFTLPKKDGVNGQVTSTKPLSYAGNLIENFTLTFENGKIVDVKAEEGEETLKHLIETDEGAKYLGEVALVPHQSPISQSNIIFYNTLFDENASNHLAIGSSYSFCLEGGKTMSKEELSQNGANDSITHVDFMIGSAEMDIDGIKADGTSEPVFRKGNWAF
>NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator
MERENMVKSVSRALDIVTIVSMEREGVGVTEIAKQMDINKSSVYRILTTLAQYGYIEQDQETGRYKLGYKFLEVSSKLLDSIDLRTEAKPFLQELESETNEVIHLVVYDQGEVVYIEKLEGNQTLRMHSKVGKRAPMHCTSVGKAILAFLPLNTVTSILERKGLPAHTDHTITDEESFLRELSEVKQKGYALDLEENEYGITCIAAPIFDHLGQVVAAVSISGATMRMTNERLTYLQERMVDIGKNISERLGYKTESVKDKSLF
>NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein
MKFVRFAVQDSRHTGVLKENTISVIKGNIFEKWDYTGQTFSPSEVRLLAPLEPNQIIGIGANYAAAKSELPREMPSIPVFFFKPTSSVIGPNDAIVIPTAIKHVKFESELAVVIGKEAKNIAKEDVLDYIFGYTIGNDVTAPDYFHEDGHWTIGKSFDSFTPLGPVIETELDFKSIHVKAFLNGVEKQNSSTDLMIISVEQMIAYLSTVMTLKPGDVVLTGSPVGAELVSANDIIECTIREIGTLRNPFAAEKERVNV

Crispr_ID: NC_014103_8

• CRISPR_ID: NC_014103_8
• CRISPR_location: 2857863-2857948
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014103_8

Consensus_repeat	Method
CTTTTGCCGTTTTTGGCGTACTA	CRISPRCasFinder

spacers of NC_014103_8

>8.1|2857886|39|NC_014103|CRISPRCasFinder
AACGAAAACTTTTGCTGTTTTTGTCGTACTACTACGTCG

CRISPR arrays and Neighbor proteins around NC_014103_8

CRISPR arrays

The CRISPR arrays of NC_014103_8

>merge|NC_014103|8|2857863-2857948|CRISPRCasFinder
CTTTTGCCATTTTTGACGTACCAAACGAAAACTTTTGCTGTTTTTGTCGTACTACTACGTCGTTTTTGCCGTTTTTTACGTACTAA

>NC_014103|8|6|2857863-2857948|CRISPRCasFinder
CTTTTGCCATTTTTGACGTACCA	AACGAAAACTTTTGCTGTTTTTGTCGTACTACTACGTCG
TTTTTGCCGTTTTTTACGTACTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013083667.1|2855968_2857432_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083669.1|2858401_2859424_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein	unknown	unknown	gnl|CDD|349995
NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein	unknown	unknown	gnl|CDD|226728
NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase	unknown	unknown	gnl|CDD|177683
NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein	unknown	unknown	gnl|CDD|372730
NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319825
NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_014103.1|WP_013083672.1|2863442_2863934_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083659.1|2847921_2848482_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase	unknown	unknown	gnl|CDD|376723
NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase	unknown	unknown	gnl|CDD|377080
NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase	unknown	unknown	gnl|CDD|377591
NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein	unknown	unknown	gnl|CDD|214615
NC_014103.1|WP_155276297.1|2849393_2849537_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein	unknown	unknown	gnl|CDD|224203
NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein	gnl|CDD|349995	cd18551, ABC_6TM_LmrA_like, Six-transmembrane helical domain of the multidrug resistance ABC transporter LmrA and similar proteins. This group represents the six-transmembrane helical domain of the multidrug resistance ABC transporter LmrA from Lactococcus lactis and similar proteins. This transmembrane (TM) subunit possesses the ATP-binding cassette (ABC) exporter fold, which is characterized by 6 TM helices per subunit (domain), or a total of 12 TM helices for the complete transporter. The ABC exporters are found in both prokaryotes and eukaryotes, where they mediate the cellular secretion of toxic compounds, a various type of lipids and polypeptides. ABC transporters typically consist of two transmembrane domains (TMDs) and two nucleotide-binding domains (NBDs). The sequences and structures of the TMDs are quite varied between the different type of transporters, suggesting significant structural diversity of the translocated substrates, while NBDs are conserved among all ABC transporters. The two NBDs together bind and hydrolyze ATP, thereby providing the driving force for transport, while the TMDs participate in substrate recognition and translocation across the lipid membrane by alternating between inward- and outward-facing conformations. Moreover, some ABC genes are organized as half-transporters, which must form either homodimers or heterodimers to form a functional transporter. The ABC exporters play a role in multidrug resistance to antibiotics and anticancer agents, and mutations in these proteins have been shown to cause severe human diseases such as cystic fibrosis.	0.00168085
NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.0693e-94
NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.91536e-58
NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein	gnl|CDD|226728	COG4278, COG4278, Uncharacterized conserved protein [Function unknown].	3.83906e-09
NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase	gnl|CDD|177683	PLN00052, PLN00052, prolyl 4-hydroxylase; Provisional.	1.23178e-41
NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein	gnl|CDD|372730	pfam13799, DUF4183, Domain of unknown function (DUF4183). This domain of unknown function contains a highly conserved ING motif.	1.45024e-05
NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase	gnl|CDD|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.16125e-44
NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.32118e-12
NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase	gnl|CDD|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase	gnl|CDD|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	5.97841e-145
NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase	gnl|CDD|377591	pfam06039, Mqo, Malate:quinone oxidoreductase (Mqo). This family consists of several bacterial Malate:quinone oxidoreductase (Mqo) proteins (EC:1.1.99.16). Mqo takes part in the citric acid cycle. It oxidizes L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial acceptors or, via the electron transfer chain, to oxygen. NAD is not an acceptor and the natural direct acceptor for the enzyme is most likely a quinone. The enzyme is therefore called malate:quinone oxidoreductase, abbreviated to Mqo. Mqo is a peripheral membrane protein and can be released from the membrane by addition of chelators.	0
NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	1.902e-24
NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein	gnl|CDD|214615	smart00318, SNc, Staphylococcal nuclease homologues.	6.16774e-38
NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein	gnl|CDD|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	7.84883e-69
NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.55281e-74

Protein sequences

>NC_014103.1|WP_013083667.1|2855968_2857432_+|hypothetical-protein
MNEPSNFSPYLIKQISDAIDDNIKAKCIDFLYDSHSFFSNEKDFIEDYILNILQDTFVLENKLINPKEIRNPAYKRRQSNKKNWLQTLKKDIKAEKPNPIFEDIELAKKVMDKKVDTEHLKKLFGVEKPEDILKIKLKEVEAWAKSKKTNITDFPYLDSKMNYQIEKAFHTDFTFLIAEIILEKYNGNLSNWIDKRLNSWVEAPIFSNESHSLKTNMEVKTNSQEVVLYNDYKVDEEYFIRTIIPVNDNQTVLSKRNMVLDPKDSQIIQFALSQRDEMFYKEKTVTLDLADIVKEIYNSKGVKNYEAVEARIMKIARYHVEGVAKKKNSRDTKFAINFFQKAVIETDEVTGRRYATIVFSDDTHQGFLNQQFVQIYSDVIKKFKDNSLSSLLLYAFQKERLDCYLQEKSYTHFYPYQYFASKVRFRSKKIDVNLKLINESLAEFVSNQVLIQSYQQKLQGFEISFIPLQNYEIQDYFGGEHRETLEG
>NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase
MLLKPKAIFLDMDGTILNRSNKVSIQTKEIIDELRKQGIFVFIATGRAFDEIEELVPEGFQVDGFITSNGMAGYVGKESVFQHSLSLQLVETIIEKARANKVYYELFPYGTPRVTLKQDQSYVENEIREPKPDSVEINEWLSRKQAIKEEIDWKDSVEGSEFSKFYFFARTHEHIDKWKEELEELKKEIDFTTSTSSKHNVEVMVANVNKATGIQQMLKHFNLPEQDILAIGDSNNDLPMFQFASYAVAMKNAPDHIKEIVDDVTEFNCDENGVSHYLSKFLLQKSTRSNPVL
>NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase
MNKRKIVYIVSDSVGETAELMVKAVLTQFSGEDIEIQNTSYVEDEGNIDNIIAEARCNEAIIAYTIVIPPLKQYLDQKAQEEGIVAIDLMTPLMSAFSQTFNKEPNLQPRLTRKLDDNYFRRVEAVEFAVKYDDGQDFRGIKRADLVLIGVSRTSKTPLSMYLAHKSLKVANIPLVPEVTPPDELFTIPKNKCIGLVITPDKLNEIRKERLKNLGLASQANYANVDRILEELDYAEKIMKRIGCPIVNVSGKAVEETAEVILSMLKKDKMKGYV
>NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase
MSNVYKKTDVILIGAGVMSATLGSLLKELAPEWEIKVFEKLADAGEESSNEWNNAGTGHAALCELNYTSEQADGSIDITKAVRINEQFQLSRQFWSYLVSSNLIHHPQEFIMPIPHMSFVQGEKNVSFLKKRFEALSNNPLFQGMEYSDRPEKLKEWMPLVMKGRTSTEASAATKIDSGTDVNFGALTRMLFTHLKSKRVEINYNHSVENLTRTADGSWEVKVHDIHTGKQEYHTANFVFIGGGGGSLSLLQKTGIPESKHIGGFPVSGLFMVCNNPEVVAQHHGKVYGKAKVGAPPMSVPHLDTRYIDRKKTLLFGPFAGFSPKFLKTGSNLDLINSVKPNNILTMLAAGVKEMGLTKYLIQQVLLSDEKRMEELREFIPNAKSEDWDIVVAGQRVQVIKDTEAGGKGTLQFGTEVVSSADGSVAALLGASPGASTAVHVMLEVLEKCFPQHMKKWESKIKEMIPSYGLSLVENPALFNEIHASTAQTLDLSKKELVYR
>NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase
MILTNTSLLTKEQTIFNHSGNKIKLEDREINIVARFEEPLVLVLGNVLSNEECDELIRLSKDKMQRSKIGAAREVNSIRTSSGMFFDESENELVHQIERRLSKIMGPSIEYAEGLQILKYLPDQEYKAHHDYFTSASKASKNNRISTLVMYLNDVEEGGETYFPKLGLSVSPTKGMAVYFEYFYSDAELNDRTLHGGAPVIKGEKWVATQWMRKQKIRS
>NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein
MKEIKAIICTMLAMFMLLLTGCSDEQASHSSTSSTDTKQAVQVEGSSDQEEDRSPSKANREDVVGEAATVERVVDGDTLKVKMLNGKRDRVRLLLVDTPETKHPKLGVQPFGPEASAYTKKRLEGQEITLEFDVQERDQYGRLLAYVWIDNELYNEELLAKGLARVAVFPPNTKYVDEFKKIQEQARKSEKGIWSIENYAQEKGYNTDAVKNQSSSKQKDTQSAKSCEGKIKGNQNSKIYHAPTGAHYNQTMNNVIWFCTEKDAQEAGYKKAKN
>NC_014103.1|WP_155276297.1|2849393_2849537_+|hypothetical-protein
MKKHRQQKDTTVSGWEVLAEILLQVPQLLIWPLRLLIRIGRSLLDGI
>NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase
MKIRKARKEDASAVTELLYDMLGSIARSHTAATTNEEALLRLKAFILSEKNRYSYHHITVAEVEEKVVGLMLCYEGSMLQTLYEPVKRFVRAKLNNPAWEIDIETEHGDYYIDSLCVDEAYRGKGIGTALLNVAKQEAKKHKMFLSLNVEYNNVEAKKLYQRIGFQEHKTIFIDKKPFFYMKTA
>NC_014103.1|WP_013083659.1|2847921_2848482_-|hypothetical-protein
MNIRDLPFNMSYRFNEQLREVPVNPHQMKQGIIYLKKRALEEEDECAAAKTYGHIGVYERILGELTSSERHLLLAIYLYDRHADTIGEFLNTIRLGHTYHWQEHWDKANETFQLLIEQLKADEDLHIYEDFVYQHYGKCLLDQRVVSRAHHYFQRALEIRLKKGDKELIESTNSCIRLCLNKLKHS
>NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein
MSKTVKDVIFLLIGSFVFSLAVNMFVIPIGLGEGGVTGISIILYYTTHLSTGSTNFILNGILLIVGYKFLEKKTIVYTMITIIATSIFLHVTEGWGLHLHEEHIGMVFAGVLLGVGIGMILRVGGTTAGSAIIARILNKFLNWKVSHALLIVDLLVVLASYFIIGIEKLLFTIVMLYIITKVIDFVIEGFDAKKAVTVILSNKNEVADQITEQLDRGVTILNGRGNYTKESKEILYVVINKQELIKLKKLIKKIDDEAFVIVHDVRDVIGKGFLSA
>NC_014103.1|WP_013083669.1|2858401_2859424_+|hypothetical-protein
MIKKEFAKIGKQIIRQLSSTVEKYKDIEDHMDLDAHGNPTIKTVAEHHRLSKSQISQLIFYHFLHVDERGIICDVSEKEIAAALNCTVRTVRNNNVVLAETELISYSRSGKGINICIVPYPQYFEEHGFGFMELEYTRFEELILIENVNALRLELRKELVYDNDTIKRQFNPAENTSKISFNDYKIFTPKYTHYKGMMQKIAETQTSAFKTVVQGSTIFFVLKDGAKNGKMSKQEKKDQYDAAIRRTIEETFVKLSGHSTDSTGIVMSSFQNEDIADLVQLSFEYGIERVKSALYSLIEQAFFSHDAQVVENYGGKIRTLIRKELSKNLQDQVPAELTAS
>NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel
MKDIQWVQQTLFNTGKWIDISEVIIKIILIFIIAQIVIRFARSVINKIFDFRFKTKLLRYNERKEITLKKLCLSIVMYVVYFIVLITSLEAIGINMKALLAGISVAGFITGLGAQNLIKDILNGFFILFEDQFSVGDHVSINDTKGTVEEIGLRTTKIRGVDGEFYFFANSNITKVANYTLGEIPEVHKPEQIKN
>NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase
MNILWDFDGTIFDTYPTIVKAFKELLTDQTISEDDILKQMKISSDIAIKHFDIEKSLFDKHFHVLEQKINPKDKPAFPHVEDVLSFADTNVIVTHKSRQSTLDILAFFNMEHYFTEIITKDDGYKRKPDSGAYAYLHDKYQLDLVIGDRELDLKPARELGIKTCAFQNDDIEADYHLTSYDQFFICSGLCTSGISPSV
>NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein
MISAIIVGAVILLALIIKGIGKPRGFRLYKEELPDELGIHGGNGFEDIVHSLEDSLPKAYVQQVKQRMQGRNTKDDEVEWTFFEIKRYFLLNAVIKDVPMFSAKVDEVWHEMIMFTVDYERFTDRFFSRFLHHQPNLETTPSPQPDKRAFFDWVYAHLFNITGNSRLLWGKFFQHPLDKSTLQDFQRLSEDELLDRYFLRNGKWEKQQRALIQTLKEEINAAQKRKKAGGSTYFKKTAKKGNVSNELLLQGFVFYSLYKATNFSSHMNELLLYKKTMYAGDAASYSGYSCSSPGEDNRHHHQHDGGHYHHDSGSSCSSSNCSSSSCSSSSCGSGCSSS
>NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein
MSLSAKKILLLVLVVICLVLVVMQFINRSAEPTSEQAQETLSKLPEQETVKEKAKGDEEAHKYRVYYITIEKIENGTYSGTTKEGTGIKFSDKNLNEPIPSNLKKGDIVKAYFDLEYSTKGLVKVEKVDEMPDDDESSS
>NC_014103.1|WP_013083672.1|2863442_2863934_+|hypothetical-protein
MMFALIVVVGIVALGVASFYVIKRPQGAVDPEDRKPLVSVNGHVKFAEGINQISISKIDMYDQRLVINQVAIIPFNRIQRAEFSKVVKNEKGLHGAPVQRYFGELTIHFTDKNGQETYIRCETPKKNQFHLIYQYDLMKRQLNKRLGLEDLQPYLTLQEPYEL
>NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein
MFPKKVRIFEYYTVAGGSKRIFTDQDALKEYDTQHILDSESYSYSNLFINGV
>NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase
MEQFERNIEKYAELAVKVGVNIQKGQILNINADISSADFVREIAKKAYEAGAKSVDVDWHDDPLVRLKYEKADESVFNEFPGWKAQAREELVKNGGAVLSVISSGPDLLKGVDGKRIAAFQKVSGKAMKKFREAIQSDKISWSIVAVPSKDWAAKVFPDVPEEQQQEKLWEAIFKSVRVDQEDPVAAWEEHNASLHTKVDILNEKRFAKLHYKAPGTDLTIELPDKHIWVGAGSVNEDGNSFMANMPTEEVFTLPKKDGVNGQVTSTKPLSYAGNLIENFTLTFENGKIVDVKAEEGEETLKHLIETDEGAKYLGEVALVPHQSPISQSNIIFYNTLFDENASNHLAIGSSYSFCLEGGKTMSKEELSQNGANDSITHVDFMIGSAEMDIDGIKADGTSEPVFRKGNWAF
>NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator
MERENMVKSVSRALDIVTIVSMEREGVGVTEIAKQMDINKSSVYRILTTLAQYGYIEQDQETGRYKLGYKFLEVSSKLLDSIDLRTEAKPFLQELESETNEVIHLVVYDQGEVVYIEKLEGNQTLRMHSKVGKRAPMHCTSVGKAILAFLPLNTVTSILERKGLPAHTDHTITDEESFLRELSEVKQKGYALDLEENEYGITCIAAPIFDHLGQVVAAVSISGATMRMTNERLTYLQERMVDIGKNISERLGYKTESVKDKSLF
>NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein
MKFVRFAVQDSRHTGVLKENTISVIKGNIFEKWDYTGQTFSPSEVRLLAPLEPNQIIGIGANYAAAKSELPREMPSIPVFFFKPTSSVIGPNDAIVIPTAIKHVKFESELAVVIGKEAKNIAKEDVLDYIFGYTIGNDVTAPDYFHEDGHWTIGKSFDSFTPLGPVIETELDFKSIHVKAFLNGVEKQNSSTDLMIISVEQMIAYLSTVMTLKPGDVVLTGSPVGAELVSANDIIECTIREIGTLRNPFAAEKERVNV

Crispr_ID: NC_014103_10

• CRISPR_ID: NC_014103_10
• CRISPR_location: 2858201-2858292
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014103_10

Consensus_repeat	Method
CTTTTGCCGTTTTTGGCGTACTA	CRISPRCasFinder

spacers of NC_014103_10

>10.1|2858224|46|NC_014103|CRISPRCasFinder
AAAATCCTATACGCTACACCCCTTGATATGACAGCATTCTTTGAAC

CRISPR arrays and Neighbor proteins around NC_014103_10

CRISPR arrays

The CRISPR arrays of NC_014103_10

>merge|NC_014103|10|2858201-2858292|CRISPRCasFinder
CTTTTGCCGTTTTTGGCGTACTAAAAATCCTATACGCTACACCCCTTGATATGACAGCATTCTTTGAACCTTTTGCCGTTTTTAGCGTACTA

>NC_014103|10|8|2858201-2858292|CRISPRCasFinder
CTTTTGCCGTTTTTGGCGTACTA	AAAATCCTATACGCTACACCCCTTGATATGACAGCATTCTTTGAAC
CTTTTGCCGTTTTTAGCGTACTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014103.1|WP_013083667.1|2855968_2857432_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083669.1|2858401_2859424_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein	unknown	unknown	gnl|CDD|349995
NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein	unknown	unknown	gnl|CDD|226728
NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase	unknown	unknown	gnl|CDD|177683
NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein	unknown	unknown	gnl|CDD|372730
NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319825
NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_014103.1|WP_013083672.1|2863442_2863934_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083659.1|2847921_2848482_-|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase	unknown	unknown	gnl|CDD|376723
NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase	unknown	unknown	gnl|CDD|377080
NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase	unknown	unknown	gnl|CDD|377591
NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein	unknown	unknown	gnl|CDD|214615
NC_014103.1|WP_155276297.1|2849393_2849537_+|hypothetical-protein	unknown	unknown	unknown
NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein	unknown	unknown	gnl|CDD|224203
NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein	gnl|CDD|349995	cd18551, ABC_6TM_LmrA_like, Six-transmembrane helical domain of the multidrug resistance ABC transporter LmrA and similar proteins. This group represents the six-transmembrane helical domain of the multidrug resistance ABC transporter LmrA from Lactococcus lactis and similar proteins. This transmembrane (TM) subunit possesses the ATP-binding cassette (ABC) exporter fold, which is characterized by 6 TM helices per subunit (domain), or a total of 12 TM helices for the complete transporter. The ABC exporters are found in both prokaryotes and eukaryotes, where they mediate the cellular secretion of toxic compounds, a various type of lipids and polypeptides. ABC transporters typically consist of two transmembrane domains (TMDs) and two nucleotide-binding domains (NBDs). The sequences and structures of the TMDs are quite varied between the different type of transporters, suggesting significant structural diversity of the translocated substrates, while NBDs are conserved among all ABC transporters. The two NBDs together bind and hydrolyze ATP, thereby providing the driving force for transport, while the TMDs participate in substrate recognition and translocation across the lipid membrane by alternating between inward- and outward-facing conformations. Moreover, some ABC genes are organized as half-transporters, which must form either homodimers or heterodimers to form a functional transporter. The ABC exporters play a role in multidrug resistance to antibiotics and anticancer agents, and mutations in these proteins have been shown to cause severe human diseases such as cystic fibrosis.	0.00168085
NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	2.0693e-94
NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.91536e-58
NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein	gnl|CDD|226728	COG4278, COG4278, Uncharacterized conserved protein [Function unknown].	3.83906e-09
NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase	gnl|CDD|177683	PLN00052, PLN00052, prolyl 4-hydroxylase; Provisional.	1.23178e-41
NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein	gnl|CDD|372730	pfam13799, DUF4183, Domain of unknown function (DUF4183). This domain of unknown function contains a highly conserved ING motif.	1.45024e-05
NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase	gnl|CDD|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.16125e-44
NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.32118e-12
NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase	gnl|CDD|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase	gnl|CDD|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	5.97841e-145
NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase	gnl|CDD|377591	pfam06039, Mqo, Malate:quinone oxidoreductase (Mqo). This family consists of several bacterial Malate:quinone oxidoreductase (Mqo) proteins (EC:1.1.99.16). Mqo takes part in the citric acid cycle. It oxidizes L-malate to oxaloacetate and donates electrons to ubiquinone-1 and other artificial acceptors or, via the electron transfer chain, to oxygen. NAD is not an acceptor and the natural direct acceptor for the enzyme is most likely a quinone. The enzyme is therefore called malate:quinone oxidoreductase, abbreviated to Mqo. Mqo is a peripheral membrane protein and can be released from the membrane by addition of chelators.	0
NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	1.902e-24
NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein	gnl|CDD|214615	smart00318, SNc, Staphylococcal nuclease homologues.	6.16774e-38
NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein	gnl|CDD|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	7.84883e-69
NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	4.55281e-74

Protein sequences

>NC_014103.1|WP_013083667.1|2855968_2857432_+|hypothetical-protein
MNEPSNFSPYLIKQISDAIDDNIKAKCIDFLYDSHSFFSNEKDFIEDYILNILQDTFVLENKLINPKEIRNPAYKRRQSNKKNWLQTLKKDIKAEKPNPIFEDIELAKKVMDKKVDTEHLKKLFGVEKPEDILKIKLKEVEAWAKSKKTNITDFPYLDSKMNYQIEKAFHTDFTFLIAEIILEKYNGNLSNWIDKRLNSWVEAPIFSNESHSLKTNMEVKTNSQEVVLYNDYKVDEEYFIRTIIPVNDNQTVLSKRNMVLDPKDSQIIQFALSQRDEMFYKEKTVTLDLADIVKEIYNSKGVKNYEAVEARIMKIARYHVEGVAKKKNSRDTKFAINFFQKAVIETDEVTGRRYATIVFSDDTHQGFLNQQFVQIYSDVIKKFKDNSLSSLLLYAFQKERLDCYLQEKSYTHFYPYQYFASKVRFRSKKIDVNLKLINESLAEFVSNQVLIQSYQQKLQGFEISFIPLQNYEIQDYFGGEHRETLEG
>NC_014103.1|WP_013083666.1|2854773_2855655_-|Cof-type-HAD-IIB-family-hydrolase
MLLKPKAIFLDMDGTILNRSNKVSIQTKEIIDELRKQGIFVFIATGRAFDEIEELVPEGFQVDGFITSNGMAGYVGKESVFQHSLSLQLVETIIEKARANKVYYELFPYGTPRVTLKQDQSYVENEIREPKPDSVEINEWLSRKQAIKEEIDWKDSVEGSEFSKFYFFARTHEHIDKWKEELEELKKEIDFTTSTSSKHNVEVMVANVNKATGIQQMLKHFNLPEQDILAIGDSNNDLPMFQFASYAVAMKNAPDHIKEIVDDVTEFNCDENGVSHYLSKFLLQKSTRSNPVL
>NC_014103.1|WP_013083665.1|2853379_2854204_-|kinase/pyrophosphorylase
MNKRKIVYIVSDSVGETAELMVKAVLTQFSGEDIEIQNTSYVEDEGNIDNIIAEARCNEAIIAYTIVIPPLKQYLDQKAQEEGIVAIDLMTPLMSAFSQTFNKEPNLQPRLTRKLDDNYFRRVEAVEFAVKYDDGQDFRGIKRADLVLIGVSRTSKTPLSMYLAHKSLKVANIPLVPEVTPPDELFTIPKNKCIGLVITPDKLNEIRKERLKNLGLASQANYANVDRILEELDYAEKIMKRIGCPIVNVSGKAVEETAEVILSMLKKDKMKGYV
>NC_014103.1|WP_013083664.1|2851756_2853259_-|malate:quinone-oxidoreductase
MSNVYKKTDVILIGAGVMSATLGSLLKELAPEWEIKVFEKLADAGEESSNEWNNAGTGHAALCELNYTSEQADGSIDITKAVRINEQFQLSRQFWSYLVSSNLIHHPQEFIMPIPHMSFVQGEKNVSFLKKRFEALSNNPLFQGMEYSDRPEKLKEWMPLVMKGRTSTEASAATKIDSGTDVNFGALTRMLFTHLKSKRVEINYNHSVENLTRTADGSWEVKVHDIHTGKQEYHTANFVFIGGGGGSLSLLQKTGIPESKHIGGFPVSGLFMVCNNPEVVAQHHGKVYGKAKVGAPPMSVPHLDTRYIDRKKTLLFGPFAGFSPKFLKTGSNLDLINSVKPNNILTMLAAGVKEMGLTKYLIQQVLLSDEKRMEELREFIPNAKSEDWDIVVAGQRVQVIKDTEAGGKGTLQFGTEVVSSADGSVAALLGASPGASTAVHVMLEVLEKCFPQHMKKWESKIKEMIPSYGLSLVENPALFNEIHASTAQTLDLSKKELVYR
>NC_014103.1|WP_013083663.1|2850850_2851510_-|2OG-Fe(II)-oxygenase
MILTNTSLLTKEQTIFNHSGNKIKLEDREINIVARFEEPLVLVLGNVLSNEECDELIRLSKDKMQRSKIGAAREVNSIRTSSGMFFDESENELVHQIERRLSKIMGPSIEYAEGLQILKYLPDQEYKAHHDYFTSASKASKNNRISTLVMYLNDVEEGGETYFPKLGLSVSPTKGMAVYFEYFYSDAELNDRTLHGGAPVIKGEKWVATQWMRKQKIRS
>NC_014103.1|WP_013083662.1|2849605_2850430_-|thermonuclease-family-protein
MKEIKAIICTMLAMFMLLLTGCSDEQASHSSTSSTDTKQAVQVEGSSDQEEDRSPSKANREDVVGEAATVERVVDGDTLKVKMLNGKRDRVRLLLVDTPETKHPKLGVQPFGPEASAYTKKRLEGQEITLEFDVQERDQYGRLLAYVWIDNELYNEELLAKGLARVAVFPPNTKYVDEFKKIQEQARKSEKGIWSIENYAQEKGYNTDAVKNQSSSKQKDTQSAKSCEGKIKGNQNSKIYHAPTGAHYNQTMNNVIWFCTEKDAQEAGYKKAKN
>NC_014103.1|WP_155276297.1|2849393_2849537_+|hypothetical-protein
MKKHRQQKDTTVSGWEVLAEILLQVPQLLIWPLRLLIRIGRSLLDGI
>NC_014103.1|WP_013083660.1|2848679_2849234_-|GNAT-family-N-acetyltransferase
MKIRKARKEDASAVTELLYDMLGSIARSHTAATTNEEALLRLKAFILSEKNRYSYHHITVAEVEEKVVGLMLCYEGSMLQTLYEPVKRFVRAKLNNPAWEIDIETEHGDYYIDSLCVDEAYRGKGIGTALLNVAKQEAKKHKMFLSLNVEYNNVEAKKLYQRIGFQEHKTIFIDKKPFFYMKTA
>NC_014103.1|WP_013083659.1|2847921_2848482_-|hypothetical-protein
MNIRDLPFNMSYRFNEQLREVPVNPHQMKQGIIYLKKRALEEEDECAAAKTYGHIGVYERILGELTSSERHLLLAIYLYDRHADTIGEFLNTIRLGHTYHWQEHWDKANETFQLLIEQLKADEDLHIYEDFVYQHYGKCLLDQRVVSRAHHYFQRALEIRLKKGDKELIESTNSCIRLCLNKLKHS
>NC_014103.1|WP_013083658.1|2846892_2847723_-|YitT-family-protein
MSKTVKDVIFLLIGSFVFSLAVNMFVIPIGLGEGGVTGISIILYYTTHLSTGSTNFILNGILLIVGYKFLEKKTIVYTMITIIATSIFLHVTEGWGLHLHEEHIGMVFAGVLLGVGIGMILRVGGTTAGSAIIARILNKFLNWKVSHALLIVDLLVVLASYFIIGIEKLLFTIVMLYIITKVIDFVIEGFDAKKAVTVILSNKNEVADQITEQLDRGVTILNGRGNYTKESKEILYVVINKQELIKLKKLIKKIDDEAFVIVHDVRDVIGKGFLSA
>NC_014103.1|WP_013083669.1|2858401_2859424_+|hypothetical-protein
MIKKEFAKIGKQIIRQLSSTVEKYKDIEDHMDLDAHGNPTIKTVAEHHRLSKSQISQLIFYHFLHVDERGIICDVSEKEIAAALNCTVRTVRNNNVVLAETELISYSRSGKGINICIVPYPQYFEEHGFGFMELEYTRFEELILIENVNALRLELRKELVYDNDTIKRQFNPAENTSKISFNDYKIFTPKYTHYKGMMQKIAETQTSAFKTVVQGSTIFFVLKDGAKNGKMSKQEKKDQYDAAIRRTIEETFVKLSGHSTDSTGIVMSSFQNEDIADLVQLSFEYGIERVKSALYSLIEQAFFSHDAQVVENYGGKIRTLIRKELSKNLQDQVPAELTAS
>NC_014103.1|WP_042452302.1|2860266_2860854_+|mechanosensitive-ion-channel
MKDIQWVQQTLFNTGKWIDISEVIIKIILIFIIAQIVIRFARSVINKIFDFRFKTKLLRYNERKEITLKKLCLSIVMYVVYFIVLITSLEAIGINMKALLAGISVAGFITGLGAQNLIKDILNGFFILFEDQFSVGDHVSINDTKGTVEEIGLRTTKIRGVDGEFYFFANSNITKVANYTLGEIPEVHKPEQIKN
>NC_014103.1|WP_013083670.1|2860799_2861396_-|HAD-IA-family-hydrolase
MNILWDFDGTIFDTYPTIVKAFKELLTDQTISEDDILKQMKISSDIAIKHFDIEKSLFDKHFHVLEQKINPKDKPAFPHVEDVLSFADTNVIVTHKSRQSTLDILAFFNMEHYFTEIITKDDGYKRKPDSGAYAYLHDKYQLDLVIGDRELDLKPARELGIKTCAFQNDDIEADYHLTSYDQFFICSGLCTSGISPSV
>NC_014103.1|WP_052303253.1|2861523_2862540_-|hypothetical-protein
MISAIIVGAVILLALIIKGIGKPRGFRLYKEELPDELGIHGGNGFEDIVHSLEDSLPKAYVQQVKQRMQGRNTKDDEVEWTFFEIKRYFLLNAVIKDVPMFSAKVDEVWHEMIMFTVDYERFTDRFFSRFLHHQPNLETTPSPQPDKRAFFDWVYAHLFNITGNSRLLWGKFFQHPLDKSTLQDFQRLSEDELLDRYFLRNGKWEKQQRALIQTLKEEINAAQKRKKAGGSTYFKKTAKKGNVSNELLLQGFVFYSLYKATNFSSHMNELLLYKKTMYAGDAASYSGYSCSSPGEDNRHHHQHDGGHYHHDSGSSCSSSNCSSSSCSSSSCGSGCSSS
>NC_014103.1|WP_013057548.1|2862615_2863035_-|hypothetical-protein
MSLSAKKILLLVLVVICLVLVVMQFINRSAEPTSEQAQETLSKLPEQETVKEKAKGDEEAHKYRVYYITIEKIENGTYSGTTKEGTGIKFSDKNLNEPIPSNLKKGDIVKAYFDLEYSTKGLVKVEKVDEMPDDDESSS
>NC_014103.1|WP_013083672.1|2863442_2863934_+|hypothetical-protein
MMFALIVVVGIVALGVASFYVIKRPQGAVDPEDRKPLVSVNGHVKFAEGINQISISKIDMYDQRLVINQVAIIPFNRIQRAEFSKVVKNEKGLHGAPVQRYFGELTIHFTDKNGQETYIRCETPKKNQFHLIYQYDLMKRQLNKRLGLEDLQPYLTLQEPYEL
>NC_014103.1|WP_157862183.1|2864314_2864473_-|DUF4183-domain-containing-protein
MFPKKVRIFEYYTVAGGSKRIFTDQDALKEYDTQHILDSESYSYSNLFINGV
>NC_014103.1|WP_013083674.1|2864725_2865958_-|aminopeptidase
MEQFERNIEKYAELAVKVGVNIQKGQILNINADISSADFVREIAKKAYEAGAKSVDVDWHDDPLVRLKYEKADESVFNEFPGWKAQAREELVKNGGAVLSVISSGPDLLKGVDGKRIAAFQKVSGKAMKKFREAIQSDKISWSIVAVPSKDWAAKVFPDVPEEQQQEKLWEAIFKSVRVDQEDPVAAWEEHNASLHTKVDILNEKRFAKLHYKAPGTDLTIELPDKHIWVGAGSVNEDGNSFMANMPTEEVFTLPKKDGVNGQVTSTKPLSYAGNLIENFTLTFENGKIVDVKAEEGEETLKHLIETDEGAKYLGEVALVPHQSPISQSNIIFYNTLFDENASNHLAIGSSYSFCLEGGKTMSKEELSQNGANDSITHVDFMIGSAEMDIDGIKADGTSEPVFRKGNWAF
>NC_014103.1|WP_013057552.1|2866101_2866896_-|IclR-family-transcriptional-regulator
MERENMVKSVSRALDIVTIVSMEREGVGVTEIAKQMDINKSSVYRILTTLAQYGYIEQDQETGRYKLGYKFLEVSSKLLDSIDLRTEAKPFLQELESETNEVIHLVVYDQGEVVYIEKLEGNQTLRMHSKVGKRAPMHCTSVGKAILAFLPLNTVTSILERKGLPAHTDHTITDEESFLRELSEVKQKGYALDLEENEYGITCIAAPIFDHLGQVVAAVSISGATMRMTNERLTYLQERMVDIGKNISERLGYKTESVKDKSLF
>NC_014103.1|WP_013083675.1|2866947_2867724_-|fumarylacetoacetate-hydrolase-family-protein
MKFVRFAVQDSRHTGVLKENTISVIKGNIFEKWDYTGQTFSPSEVRLLAPLEPNQIIGIGANYAAAKSELPREMPSIPVFFFKPTSSVIGPNDAIVIPTAIKHVKFESELAVVIGKEAKNIAKEDVLDYIFGYTIGNDVTAPDYFHEDGHWTIGKSFDSFTPLGPVIETELDFKSIHVKAFLNGVEKQNSSTDLMIISVEQMIAYLSTVMTLKPGDVVLTGSPVGAELVSANDIIECTIREIGTLRNPFAAEKERVNV

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_014103_4	4.8|1377761|42|NC_014103|CRT	1377761-1377802	42	NC_014103.1	1377785-1377826	2	0.952

1. spacer 4.8|1377761|42|NC_014103|CRT matches to position: 1377785-1377826, mismatch: 2, identity: 0.952

aagaacgacgagaagaaccacgagaagaaccacgagaagaac	CRISPR spacer
aagaaccacgagaagaacgacgagaagaaccacgagaagaac	Protospacer
****** *********** ***********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP025188	Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence	4755-4784	6	0.8
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	MT498059	Gordonia phage Doggs, complete genome	5032-5061	6	0.8
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP016289	Rhizobium leguminosarum strain Vaf10 plasmid unnamed2, complete sequence	610558-610587	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NC_020894	Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence	74773-74802	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP030828	Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence	179582-179611	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NC_017766	Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence	74774-74803	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP013558	Rhizobium phaseoli strain N841 plasmid pRphaN841a, complete sequence	9930-9959	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP013506	Rhizobium sp. N1341 plasmid pRspN1341a, complete sequence	10960-10989	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP013569	Rhizobium phaseoli strain N771 plasmid pRphaN771a, complete sequence	12414-12443	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NC_004689	Mycobacterium phage Barnyard, complete genome	41518-41547	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	MT771339	Gordonia phage Archimedes, complete genome	4083-4112	7	0.767
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP033036	Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence	121200-121229	8	0.733
NC_014103_4	4.5|1377641|30|NC_014103|CRT	1377641-1377670	30	NZ_CP033583	Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence	40510-40539	8	0.733
NC_014103_3	3.2|1178324|30|NC_014103|CRT	1178324-1178353	30	NZ_CP016289	Rhizobium leguminosarum strain Vaf10 plasmid unnamed2, complete sequence	610554-610583	9	0.7
NC_014103_1	1.1|332011|34|NC_014103|CRISPRCasFinder	332011-332044	34	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	347341-347374	10	0.706

1. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP025188 (Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence) position: , mismatch: 6, identity: 0.8

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
atgggcggcgagacgagcggcgagacgagc	Protospacer
  *..******** *********** ****

2. spacer 4.5|1377641|30|NC_014103|CRT matches to MT498059 (Gordonia phage Doggs, complete genome) position: , mismatch: 6, identity: 0.8

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gcgaacgacgcgaagagcggcgagaaggtc	Protospacer
  *****.** ****************. *

3. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP016289 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
ggtgcgggcgagaagagcggcgagaagagg	Protospacer
 . .  *********************** 

4. spacer 4.5|1377641|30|NC_014103|CRT matches to NC_020894 (Streptomyces hygroscopicus subsp. jinggangensis TL01 plasmid pSHJGH1, complete sequence) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gacgacggcaagaagagcggcgagaagccg	Protospacer
 * .*****.*****************   

5. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP030828 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gagaatggcgagaagagcggcgagcacttg	Protospacer
 ****.****************** *    

6. spacer 4.5|1377641|30|NC_014103|CRT matches to NC_017766 (Streptomyces hygroscopicus subsp. jinggangensis 5008 plasmid pSHJG1, complete sequence) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gacgacggcaagaagagcggcgagaagccg	Protospacer
 * .*****.*****************   

7. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP013558 (Rhizobium phaseoli strain N841 plasmid pRphaN841a, complete sequence) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gagaacggcgagaagatcggcgggcgcacc	Protospacer
 *************** *****.* . * *

8. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP013506 (Rhizobium sp. N1341 plasmid pRspN1341a, complete sequence) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gagaacggcgagaagatcggcgggcgcacc	Protospacer
 *************** *****.* . * *

9. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP013569 (Rhizobium phaseoli strain N771 plasmid pRphaN771a, complete sequence) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gagaacggcgagaagatcggcgggcgcacc	Protospacer
 *************** *****.* . * *

10. spacer 4.5|1377641|30|NC_014103|CRT matches to NC_004689 (Mycobacterium phage Barnyard, complete genome) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gaggctggcgagaagatcggcgagaaggtc	Protospacer
 **. .********** **********. *

11. spacer 4.5|1377641|30|NC_014103|CRT matches to MT771339 (Gordonia phage Archimedes, complete genome) position: , mismatch: 7, identity: 0.767

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
aagtcgggcgagaagggcggcgagaaggac	Protospacer
 **   *********.***********..*

12. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP033036 (Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence) position: , mismatch: 8, identity: 0.733

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
atcgacggcgagaagatcggccagaagcgg	Protospacer
   .************ **** ***** * 

13. spacer 4.5|1377641|30|NC_014103|CRT matches to NZ_CP033583 (Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence) position: , mismatch: 8, identity: 0.733

tagaacggcgagaagagcggcgagaagagc	CRISPR spacer
gacgacgacaagaagagcggcgagaagccg	Protospacer
 * .***.*.*****************   

14. spacer 3.2|1178324|30|NC_014103|CRT matches to NZ_CP016289 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

acggcgagtagagcggcgagtagagcgata	CRISPR spacer
cgggcgagaagagcggcgagaagaggtcgc	Protospacer
  ****** *********** ****     

15. spacer 1.1|332011|34|NC_014103|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 10, identity: 0.706

ccctggggaaggtgacggaactcagccagatccg	CRISPR spacer
acctgtggaaggcgacggaactcagcttgccgga	Protospacer
 **** ******.*************. * .  .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	241041 : 249303	8	Synechococcus_phage(50.0%)	NA	NA
DBSCAN-SWA_2	2152621 : 2160834	7	Bacillus_virus(66.67%)	NA	NA
DBSCAN-SWA_3	4203494 : 4212797	8	Bacillus_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_014103|241041:249303|DBSCAN-SWA
CATGATTGAACGTTATACAAGACCAGAAATGGCAGCTATTTGGACAGAAGAAAATAAATTTAAAGCTTGGTTAGAAGTTGAAATTCTAGCTTGTGAAGCATGGTCAGAATTAGGACATATTCCGAAAGAAGATGTGAAGTTAATTCGTCAAAATGCATCTTTTGATATTAACCGCATCAATGAAATTGAACTAGAAACGCGTCATGACGTAGTAGCTTTCACTCGTGCAGTATCTGAAACGCTTGGTGAAGAGCGCAAGTGGGTACACTACGGTTTGACTTCAACTGACGTAGTTGATACAGCTCTATCTTATTTATTAAAGCAAGCTAATGAAATCTTGCTAAGTGACGTAGAGCGCTTTGTAGAAGTACTAAAGGAAAAAGCTCAAGAACATAAGTATACGGTTATGATGGGACGTACGCACGGTGTACACGCTGAGCCAACGACATTTGGTTTGAAAATGGGATTATGGTATGAAGAAATGAAGCGTAACCTAGAGCGTTTAAAACGTGCTGCAGCTGAAGTGGAATTCGGTAAAATGTCAGGAGCAGTTGGAACGTTCGCTAACATCGATCCTTTCGTTGAAAAATACGTATGTGAGAAGTTAGGAATTTCACCAGCACCAATCTCTACGCAAACATTACAGCGTGACCGTCATGCACACTATATGTCAGTACTAGCGTTAATTGCGACATCTATTGAGAAATTTGCAGTAGAAGTTCGTGGTCTTCAAAAGAGTGAAACACGTGAGGTTGAAGAGTACTTTGCAAAAGGTCAAAAAGGATCATCTGCAATGCCTCATAAACGTAATCCAATCGGTTCTGAGAACGTAACGGGACTTGCTCGCTTAATTCGCGGCTATATGGTTACAGCTTATGATAATGTACCGCTTTGGCATGAGCGTGACATCTCTCATTCATCGGCAGAGCGTGTCATCTTACCTGATGCAACGATTGCTTTAAATTACATGTTAAATCGTTTTGCAAATATTGTTAAAAACTTAACAGTATTCCCTGACAACATGAAGCGCAACATGGACCGTACACTAGGGCTAATTTATTCACAGCGTGTACTGTTAACACTAATCAATAAAGGCATGGTACGCGAAGAAGCATACGACTTAGTACAGCCAAAAGCAATGGAAGCATGGGAAACGCAAGTTCCTTTCCGTTCTTTAATTGAAGGCGAAGAGCGCATTACTCGCCACTTATCACCAGAAGAGATTGAAGATTGCTTCGATCATAAGCACCATTTAAAAAATGTAGATATGATTTTTGAACGTTTAGGTCTTTAATAAAAAAGGCAAGGCACGTCCTTGCCTTTATCTAAGAAAGTGTATCTGAATATTCTGTATGTAGAGGTGACAGCATGGAAAAGCAAGAGTTACTTTATGAAGGAAAAGCGAAAAAAATTTACGCTACTGATGAGCAAGATGTATTGTGGGTTGCTTATAAAAATGAAGCTACAGCATTCAACGGTCAGAAAAAAGCAGAGATTAGCGGAAAAGCACAGTTGAACAATCAAATTAGTAGTTTACTATTTTCAATGTTACATGAGCAAGGGATTACAACTCACTTTGTGAAGCAGCTTTCAGATTATGAACAAGCGGTTAAGAAAGTAGAAATTGTTCCGCTTGAAGTTGTTGTACGAAATGCTACAGCAGGAAGCCTTGCGAAGCGAATTGGCGTAGAAGAAGGTATTCGTTTTGAACAGCCAATCGTTGAACTTTACTACAAAGATGATGCGCTTGGTGATCCATTAATTCTTGCAGAACATGCGATTTTCCTTAAGGCTGCAACTCAAGAAGAGATTGATAGTTTAAAGGCACAAGCACTTCAAATCAACGAAGTATTATCGAAATTTTTCAAGGATAAAGATATTTTCTTAGTAGATTTTAAATTAGAATTCGGCCGTACTTCTCAAGGCGACATTATTTTAGCGGATGAAATTTCACCTGACACTTGCCGCTTCTGGGATGTTCATACGAACGAAAAATTAGATAAAGATGTATTCCGCAGAGATTTAGGCGGTTTAACAGAAGCATACGAAAAAATCTTACAGCGAATCGGAGGATAACCCAACCATGTATAAAGTAAAAGTATTTGTCACATTAAGAGAAAGTGTATTAGACCCTCAAGGAGTAGCCGTTAAAAATTCATTGCACCGTATGTCTTATGAAGAAGTAGAAGAAGTACGCATCGGTAAATTTTTAGAGCTAACAATCGACAGCACAGATTCATTAGATGAACGAGTAAAAGAAATGTGTGAAAAGCTTTTAGTTAATACAGTAATTGAAGATTACCGTTACGAGGTTGAGGAGGTTGTCGTACAGTGAAATTTGCTGTAATTGTTTTTCCAGGATCAAACTGTGACGTCGATATGTATCATGCTATCAAAGATGAGCTTGGTGAAGAAGTAGATTACGTTTGGCATGATACAGAATCATTAGATCAATATGATGGTATCTTGCTTCCAGGTGGTTTCTCATATGGAGATTACCTTCGTTCAGGTGCTATCGCTCGCTTCTCAAATGTAATGGACGCTGTAAAAAAAGCAGCAAGCCAAGGAAAGCCAGTACTAGGTGTATGTAATGGATTCCAAATTTTATTAGAAGCAGGATTACTGCCAGGTGCTATGCGCCGTAATGAAAACTTAAAATTCATCTGTAAAACAGTGAATTTGAAAGTAGCTAATAACGAAACAATGTTTACAAATGCTTATGGCAAAGATGAAGTAATTGCTATTCCAGTGGCACACGGTGAAGGCAACTACTATTGTGATGAACACACGTTACAAAAATTGATTGAAAACAACCAGATTCTTTTCCAATACGCAGGTGATAATCCAAATGGAAGTCTTCAAGATATTGCAGGGATTACGAACGAAACAGGCAACGTATTAGGAATGATGCCTCACCCAGAAAGAGCGGTAAGCGATCTTTTAGGAAGCGCAGACGGACTTAAATTATTTCAATCAATCGTAAAGCAGTGGAGGGAACAAAATGTCGTTACTTCTTGAACCAAATGTAGAGCAAATTAAAGAACAAAAGTTATATCGAGACATGGGATTAACAGACGAAGAGTTTGCGAATGTAGAGCAACTGCTTGGTCGTACTCCTAATTATACAGAAACAGGCTTATTCTCTGTTATGTGGTCAGAGCACTGCAGTTATAAAAACTCTAAGCCTGTACTGAAAAAATTCCCTATCACGGGTGAAAAAGTATTACAAGGTCCTGGTGAAGGAGCTGGTATCGTTGATATTGGTGACAACCAAGCCGTTGTATTTAAAATCGAAAGTCATAACCATCCATCAGCGATTGAACCTTATCAAGGAGCAGCAACTGGTGTAGGTGGTATCATTCGTGACGTCTTTTCAATGGGAGCAAGACCGATTGCACTTTTAAACTCTTTGCGTTTTGGTGAATTAACATCTCCAAAGGTTCGTCATTTGTTTGAGGAAGTAGTAGCGGGAATCGCGGGTTACGGTAACTGTGTAGGAATCCCAACAGTAGGCGGAGAAATTCAGTTTGAAGCTTCATATGAAGGAAATCCGCTTGTTAACGCTATGTGTGTGGGTTTAATTAATCACGAAGATATTCAAAAAGGTCAAGCTAAAGGCATTGGCAACACGGTTATGTACGTAGGAGCAAAAACCGGCCGCGACGGCATCCACGGCGCAACATTTGCTTCTGAAGAACTATCTGATCAGTCAGATGAAAAACGTCCTGCTGTACAAGTAGGAGATCCATTTATGGAAAAGCTTCTTCTTGAAGCTTGCCTAGAACTTATCAAGTGTGACGCTTTAGTCGGTATTCAAGATATGGGTGCTGCGGGCTTAACAAGTTCTTCAGCAGAGATGGCAAGTAAAGCGGGTTCTGGTATTGAAATGAACCTTGATCTTGTACCTCAGCGTGAAACAGGTATGACACCATATGAAATGATGCTTTCGGAATCTCAAGAGCGCATGCTCATCGTTGTTGAAAAAGGCCGTGAAAATGAAATCGTAGAAATCGTAGAAAAATACGGATTAGAAGCTGTTTCAGTTGGTCACGTAACCGACGATAAGCGCCTTCGTTTAACTCATAACGGAGAAGTAGTAGCAGATGTTCCTGTAGATGCATTAGCAGAAGATGCACCGGTATACCACAAGCCATCTCAAGAACCAGCATACTATCGTGAGTTCCAAGAGCAATCAGCATATGCTCCTACTGTTGAAAATCACAGTGATATGTTAGTAACACTTTTAAAACAGCCTACTATTGCAAACAAAGAGTGGGTTTACAACCAATATGACTATCAAGTACGTACAAACACAGTTGTATCTCCTGGATCTGATGCGGCGGTTGTTCGTGTACGTGATACAAATAAAGCATTAGCGATGACAACAGACTGTAACTCTCGCTATTTATACCTAGACCCAGAAGTAGGCGGCCGTATTGCAGTAGCAGAAGCTGCTCGTAACCTTGTATGTTCAGGTGCACAGCCTCTTGCAATTACAGACTGCTTAAACTTCGGTAACCCTGAAAAACCAGAAATCTTCTGGCAAATTGAAAAAGCAACAGACGGTATGAGCGACGCTTGCCGTAAGCTATCGACTCCGGTTATCGGCGGTAACGTATCTCTTTACAATGAAACAAAAGGTGAAGCAATTTACCCAACTCCTGTTATCGGAATGGTTGGTTTGATCGACGATATCAACCATATTACAACTCAATATGCGAAGCAAAAAGATGACTTAATCTATGTTATTGGTAAAGCTGAAGCAGAATTCGCAGGTACTGAGCTTCAAAAAGTACTAGAAAACGGTACGGTATTTGGGCATTCACCTAAATTAGATTTAGCAGTTGAAAAAACACGTCAAGATCAGCTTCTTCAAGCAATTCGTGAAGGCGCAGTTCAATCTGCTCACGATATTGCAGAAGGAGGATTCGCGGTAGCCCTAGCTGAAAAAGTGATGAACGGCAGCGGATTAGGTGTGGACGTAACGGTAGACGGCGAAGCAACAGCAGAGCTATTCAGTGAAACACAATCACGTTTTATCGTAACGGTTTCTCCAGAGAATAAAGAAAAATTCGAAAAGCTTGTACAAGATGTAACATTAGTAGGACGCGTAACAGAAGACGCAACATTAACTGTTAAACATCAAGAAAATGTTCTTGTTCAATTATCAGTTGAAGAATTAACTACTGCTTGGAAAGGAGCGCTTCCATGCTTGCTGAAATCAAAGGCTTAAACGAAGAATGTGGCGTATTCGGTGTATGGGGACATGAAAATGCAAGCCAGATTGCTTATTACGGTTTGCATAGCTTGCAGCACCGCGGACAAGAAGGCGCTGGTATTGCTGTAACAGACGGAGAAAAAGTGACAGTAATGAAAGGTGTCGGTCTTGTTAACGAAGTATTTGGCCACGGAGAGTTAGAGCAACTAAACGGTAAAGCAGCAATTGGACACGTTCGTTATGCAACAGCTGGAGGCGGAGGGTTTGAAAATGTTCAACCCCTTCACTTCCGCTCTCATAGCGGAAGCCTTGCGTTAGCTCATAATGGAAACTTGGTTAATGCAAATGCATTAAAGCATCAGCTGGAAAACCAAGGGAGTATTTTTCAATCAACATCAGATACAGAAGTACTTGCTCATTTAATTAAACGAAGCGGCTATGAAGATATGAAAGATAAAGTAAAAAATGCTTTATCCATGGTTAAAGGCGCATACGCATTCGTTATCTTAACAGAAGATACGATGATGGTTGCACTTGACCCTCACGGATTGCGTCCGTTATCAATTGGACGATTAGGTGATGCTTATGTAGTAGCTTCTGAAACATGTGCGTTTGATATTGTTGGAGCAGTTCATGAGCGTGATGTAGAGCCGGGTGAATTACTCATTATTAACGATGAAGGTATTCAATCAGAACGTTTCACATTAAATGTAAACCGCGCAATTTGCAGTATGGAATATATTTATTTCTCAAGACCAGACAGTAATATTGATGGAATCAATGTTCACTCTGCTCGTAAAAACCTTGGGAAACAACTTGCAGTTGAGTCACCGATTGAAGCAGACGTTGTAACAGGCGTTCCCGATTCAAGTATTTCAGCAGCGATCGGTTTTGCAGAACAGTCAGGAATTCCATACGAATTGGGTTTAATTAAGAATCGATACGTAGGCCGTACGTTCATTCAGCCTTCACAAGAATTGCGTGAACAAGGTGTGAAAATGAAGCTGTCTCCTGTACGTAAAATTGTAGAGGGTAAACGTGTTGTCATGGTAGATGACTCTATCGTTCGCGGCACAACAAGCCGTCGCATTGTTCGTATGCTTCGAGAAGCAGGAGCAACTGAAGTACATGTACGCATCAGTTCACCCCCTATCAAAAATCCATGTTTTTATGGAATTGACACGTCGTCATCCTCTGAGCTAATTGCTGCTACGCGCTCTGTTGAAGAAATTCGTGAATTGATTGAAGCTGATTCACTTGTTTTCTTAAGCAACGAAGGGTTAGTAGATGCAATCGGCAGACAGTATGAAGGCAACGGCGGACAGTGTATGGCATGTTTCACTGGAAAGTATCCAACTGAAATTTATCCAGATACTGTACACCCTCATGAAAAGGTAACTTGTTAGTTTTAACGTAAAAAAGGAGTGACAACATGTCATATTCATATAAACAAGCTGGAGTTGACTTAGAAGCAGGATATGAAGCTGTTTCACGTATTAAAAAGCACGTAGAACGCACTGCTCGTGCAGGTATTATGGGAACAGTGGGTGGCTTTGGCGGAATGTTCGATTTATCTACATTGAATTTAAAAGAGCCTGTTCTTGTTTCTGGTACAGATGGAGTAGGAACAAAATTGAAACTTGCTTTTCAAATGGATAAGCATGACACAATCGGTGTGGATGCAGTGGCCATGTGTGTAAACGACGTTTTAGCACAAGGAGCAGAGCCTCTTTACTTCTTAGATTATATTGCTTGCGGGAAAGCAGTTCCTGAAAAAATTGAATCGATTGTAAAAGGAATTGCAGACGGCTGTGAACAATCCAACTGTGCGTTAATTGGCGGAGAAACAGCTGAAATGCCAGGTTTATACGAAGAAGATGAATATGATCTTGCAGGGTTTACAGTAGGAGCAGTAGAAAAGTCAGAAATTATTACTGGAGATGAGATTAAAGCTGGACAGCTGTTGATCGGTATTTCATCTAGCGGTATCCACAGCAATGGCTACTCTCTTGTACGTAAAATCGTTGATGATCAAGGATTAAATCTTCAAGAAACTTACGCTGGTTTTAACGAAAAGCTTGGAGTTGAGTTATTAACACCAACAAAAATATACGTGAAGCCGGTCCTAAAAGCATTACATGCAGCTAAGATTGCAGGTATGGCTCATATTACTGGAGGCGGATTTGTTGAAAATATCCCTCGTATGCTTCCTGAAGGTTTAGGTGTAGAAATCGATTATGGTTCTTGGCCAATTCCATACGTGTTTGATTTCCTTGAAGAGCAAGGCAAGCTAGACCGTAAAGAAATGTTCGAAGTATTCAACATGGGAATCGGATTTGTTTTAGCTGTTGAACCTGAAGATATGAATAAAGTCATTGAAGCAATTGAAAACGAAGGCGAAAAAGCATTTGTTATCGGACGTGTCAAAGAAGGAACAGGTGTTGAATTTGCTGGAGGGACGTTTGCATGATAAATATTGCAGTGTTTGCTTCTGGAAACGGCAGTAACTTTCAATCCATCTACGAAGCAACTCAGTCAGGTCGATTAAAAGCAAATATCGCGCTTGTTGTTTGCAATAAACCCGATGCATACGTAATTGAACGAGCAAAAGCATGTGGAATACCATGCTTTGTTTGTTCGCCTAAAAACTATGAAAATAAAGAAGCGTATGAAGCAGCAATTCTTGCAGAGCTTACATCAGCTAAAGTAGAATTTCTTGTTTTAGCAGGATATATGCGATTAGTTGGTTCGACGTTGCTTAAGCCATACAAAAATCGTATTGTTAATATTCATCCGTCGCTTTTACCTGCATTTCCTGGGATTGATGCTATTGGTCAAGCTTTTGATGCAGGAGTAAAAGTGATTGGAATTACCGTGCATTTTGTAGATGAAGGAATGGATACAGGACCAATTATTGATCAGCAGGCTATTCGCATTGAAAAAGGCGATACAAGAGAAACAGTCGAGGCCCGCATTCATGAAATTGAACATCAATTTTATCCCGCGGTACTAAATGAATTATTTAAACAAGCCGCAGTTAAATAA

Protein sequences of DBSCAN-SWA_1

>NC_014103|241041:249303|244041_246273_+|WP_013081440.1|DBSCAN-SWA
MSLLLEPNVEQIKEQKLYRDMGLTDEEFANVEQLLGRTPNYTETGLFSVMWSEHCSYKNSKPVLKKFPITGEKVLQGPGEGAGIVDIGDNQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIALLNSLRFGELTSPKVRHLFEEVVAGIAGYGNCVGIPTVGGEIQFEASYEGNPLVNAMCVGLINHEDIQKGQAKGIGNTVMYVGAKTGRDGIHGATFASEELSDQSDEKRPAVQVGDPFMEKLLLEACLELIKCDALVGIQDMGAAGLTSSSAEMASKAGSGIEMNLDLVPQRETGMTPYEMMLSESQERMLIVVEKGRENEIVEIVEKYGLEAVSVGHVTDDKRLRLTHNGEVVADVPVDALAEDAPVYHKPSQEPAYYREFQEQSAYAPTVENHSDMLVTLLKQPTIANKEWVYNQYDYQVRTNTVVSPGSDAAVVRVRDTNKALAMTTDCNSRYLYLDPEVGGRIAVAEAARNLVCSGAQPLAITDCLNFGNPEKPEIFWQIEKATDGMSDACRKLSTPVIGGNVSLYNETKGEAIYPTPVIGMVGLIDDINHITTQYAKQKDDLIYVIGKAEAEFAGTELQKVLENGTVFGHSPKLDLAVEKTRQDQLLQAIREGAVQSAHDIAEGGFAVALAEKVMNGSGLGVDVTVDGEATAELFSETQSRFIVTVSPENKEKFEKLVQDVTLVGRVTEDATLTVKHQENVLVQLSVEELTTAWKGALPCLLKSKA
>NC_014103|241041:249303|241041_242334_+|WP_013055036.1|DBSCAN-SWA
MIERYTRPEMAAIWTEENKFKAWLEVEILACEAWSELGHIPKEDVKLIRQNASFDINRINEIELETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTALSYLLKQANEILLSDVERFVEVLKEKAQEHKYTVMMGRTHGVHAEPTTFGLKMGLWYEEMKRNLERLKRAAAEVEFGKMSGAVGTFANIDPFVEKYVCEKLGISPAPISTQTLQRDRHAHYMSVLALIATSIEKFAVEVRGLQKSETREVEEYFAKGQKGSSAMPHKRNPIGSENVTGLARLIRGYMVTAYDNVPLWHERDISHSSAERVILPDATIALNYMLNRFANIVKNLTVFPDNMKRNMDRTLGLIYSQRVLLTLINKGMVREEAYDLVQPKAMEAWETQVPFRSLIEGEERITRHLSPEEIEDCFDHKHHLKNVDMIFERLGL
>NC_014103|241041:249303|243123_243375_+|WP_013055038.1|DBSCAN-SWA
MYKVKVFVTLRESVLDPQGVAVKNSLHRMSYEEVEEVRIGKFLELTIDSTDSLDERVKEMCEKLLVNTVIEDYRYEVEEVVVQ
>NC_014103|241041:249303|247690_248728_+|WP_013081441.1|DBSCAN-SWA
MSYSYKQAGVDLEAGYEAVSRIKKHVERTARAGIMGTVGGFGGMFDLSTLNLKEPVLVSGTDGVGTKLKLAFQMDKHDTIGVDAVAMCVNDVLAQGAEPLYFLDYIACGKAVPEKIESIVKGIADGCEQSNCALIGGETAEMPGLYEEDEYDLAGFTVGAVEKSEIITGDEIKAGQLLIGISSSGIHSNGYSLVRKIVDDQGLNLQETYAGFNEKLGVELLTPTKIYVKPVLKALHAAKIAGMAHITGGGFVENIPRMLPEGLGVEIDYGSWPIPYVFDFLEEQGKLDRKEMFEVFNMGIGFVLAVEPEDMNKVIEAIENEGEKAFVIGRVKEGTGVEFAGGTFA
>NC_014103|241041:249303|248724_249303_+|WP_013081442.1|DBSCAN-SWA
MINIAVFASGNGSNFQSIYEATQSGRLKANIALVVCNKPDAYVIERAKACGIPCFVCSPKNYENKEAYEAAILAELTSAKVEFLVLAGYMRLVGSTLLKPYKNRIVNIHPSLLPAFPGIDAIGQAFDAGVKVIGITVHFVDEGMDTGPIIDQQAIRIEKGDTRETVEARIHEIEHQFYPAVLNELFKQAAVK
>NC_014103|241041:249303|246248_247664_+|WP_013055041.1|DBSCAN-SWA
MLAEIKGLNEECGVFGVWGHENASQIAYYGLHSLQHRGQEGAGIAVTDGEKVTVMKGVGLVNEVFGHGELEQLNGKAAIGHVRYATAGGGGFENVQPLHFRSHSGSLALAHNGNLVNANALKHQLENQGSIFQSTSDTEVLAHLIKRSGYEDMKDKVKNALSMVKGAYAFVILTEDTMMVALDPHGLRPLSIGRLGDAYVVASETCAFDIVGAVHERDVEPGELLIINDEGIQSERFTLNVNRAICSMEYIYFSRPDSNIDGINVHSARKNLGKQLAVESPIEADVVTGVPDSSISAAIGFAEQSGIPYELGLIKNRYVGRTFIQPSQELREQGVKMKLSPVRKIVEGKRVVMVDDSIVRGTTSRRIVRMLREAGATEVHVRISSPPIKNPCFYGIDTSSSSELIAATRSVEEIRELIEADSLVFLSNEGLVDAIGRQYEGNGGQCMACFTGKYPTEIYPDTVHPHEKVTC
>NC_014103|241041:249303|242408_243116_+|WP_013081439.1|DBSCAN-SWA
MEKQELLYEGKAKKIYATDEQDVLWVAYKNEATAFNGQKKAEISGKAQLNNQISSLLFSMLHEQGITTHFVKQLSDYEQAVKKVEIVPLEVVVRNATAGSLAKRIGVEEGIRFEQPIVELYYKDDALGDPLILAEHAIFLKAATQEEIDSLKAQALQINEVLSKFFKDKDIFLVDFKLEFGRTSQGDIILADEISPDTCRFWDVHTNEKLDKDVFRRDLGGLTEAYEKILQRIGG
>NC_014103|241041:249303|243371_244058_+|WP_013055039.1|DBSCAN-SWA
MKFAVIVFPGSNCDVDMYHAIKDELGEEVDYVWHDTESLDQYDGILLPGGFSYGDYLRSGAIARFSNVMDAVKKAASQGKPVLGVCNGFQILLEAGLLPGAMRRNENLKFICKTVNLKVANNETMFTNAYGKDEVIAIPVAHGEGNYYCDEHTLQKLIENNQILFQYAGDNPNGSLQDIAGITNETGNVLGMMPHPERAVSDLLGSADGLKLFQSIVKQWREQNVVTS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013055036.1|241041_242334_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	5.9e-19	25.5
WP_013081439.1|242408_243116_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FGF0	Synechococcus_phage	3.5e-42	39.7
WP_013055038.1|243123_243375_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_013055039.1|243371_244058_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_013081440.1|244041_246273_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	7.2e-158	41.3
WP_013055041.1|246248_247664_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.3e-55	34.6
WP_013081441.1|247690_248728_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F0L1	Synechococcus_phage	1.7e-69	45.6
WP_013081442.1|248724_249303_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.1e-29	39.2

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_014103|2152621:2160834|DBSCAN-SWA
AATGTCGAACAATAAAGCAATGACGAATCAAACGAAAAAAGAATACCCTAAACCCTATGGCTATACGTCAGATATTGCTGTATTTACGATTGTGACGGAAGAAAAAGAACCATACAAACCACCTAAAATGAGTTTGAAATTAATGCTTATCCAACGAGCAATGGTGAATGCAGAGGGAGAAAAGAACAGCGAAGCAGGAAAGTGGGCGCTTCCCGGCGGATTTGTCCATCCTGATGAATCAGCTTTTGAAGCGGCTAAAAGAGAGCTCGAAGAAGAAACGGGCGTAAAGGATATTCATTTAAAACACTATGGTGTCTATGATGAGCCTGGCAGGGACGATAGAGGATGGGTCATTACAAACGCACATTATGCAATCGTTCCAGAAGATAGCCTAATAAAGCGAAAAGCGAATGATGATGCTGCTCGAGTTGAATTGTTTAAAATAGATGAAATTTTTTCATTGCCTTTAGCTTTTGATCATGAAATCATCATTCGAGATGCAATCAAGGAAATTAAGAAAGATTTATTGCAAACGACCATTGCCCAGAAATTTCTGCCTCCTCAGTTTACATACTCTGAGCTGCAGGCTGTGCTGCTTACCGTAACGGATGATGCAGCGATTAAAAGTGATCAGGCCTTTGCACGAAAAATAAGAATGCTGCCATTTATTGAAGAAGTAGACGGAAAAACAACGACGAGAACGTCTAAAAAACCAACAAAGCTCTACCGGTTTGTTGAAATGAATGTGATGAAGCCAATCTATACAGCACGCTATTAAAAGAAAAACTTTCAGTTCAAATAATTAACAATATGTTAACTGTTAATTTTCACATATGAGGGGGAAACATAATGAAAAAAGCACTGATTAACATCGATTATACAAATGATTTTGTAGCTGAAAACGGAGCTTTGACATGCGGAGAACCAGGGCAACAAATTGAAACATTCATAAGCGATATTACGCGTCAATTTATTGAGCAAAACGAGTATGTGGTGTTCGCCATTGATTTTCATAAAGAAAATGATTCCTTGCATCCAGAATCAGCGCTGTTTCCGCCTCATAATGTTGAAGGCTCTGCAGGAAGAGAGCTATATGGAAAGTTAAATGATTTATATAATGTGTATCAATCACAGGCAAATGTAGAATGGATGAATAAAACGAGATACAGCGCATTTGCTGGAACGGATCTGGAGATTAAACTGAGAGAAAGGCAGATTACCGATGTCTACTTAGCAGGTGTATGTACGGATATTTGTGTACTTCATACAGCAGTAGATGCCTATAATAAAGGATTTGCTATTTATATTTATGAAAAAGCCGTAGCAAGCTTTAATCAAAAAGGCCATGAGTGGGCGCTTGAACACTTTAAATCTTGCCTCGGAGCAGAAATTATTTAAGGACATAAAAGTGGAGGAAATCAATGAATATGTTTACAGATGACAGCGTAATGCTACACACCGATTTATATCAAATTAATATGGGAGAAACGTACTGGGAAGATAATATTCATCAAAAGAAGGCTGTTTTTGAAGTTTTCTTCCGCAAACTTCCTTTTGGAAATGGCTATGCTGTTTTTGCTGGATTAGAAAGAATTATTGAATATATTAAAGCATTTAAATTTAGCGAATCAGATTTAACCTACTTGCACGAAGAATTAGGTTTTAAAGAAGATTATTTAGCTTACTTAAAAGACCTTACGTTTACTGGAACGATTCGATGTATGCGTGAAGGTGAGCTTGTATTTCATAATGAACCAATTTTACGTGTAGAAGCACCATTAATTGAAGCTCAGCTCGTAGAAACAGCGATTTTAAATATTGTGAATTACCAAACGCTGATTGCAACGAAAGCAGCTCGAATCAAACATGTAGTAGGAGATCAAGTGGCAATGGAATTTGGAACACGCCGCGCTCAAGAAATGGACGCTGCCATTTGGGGAACAAGAGCAGCCTATATTGGCGGATTTAGTGCTACTTCTAACGTGCGAGCAGGAAAGAAATTTGGAATTCCAGTGGCAGGAACGCATGCTCATGCGATGGTGCAAGCTTATAAAGACGAATACATTGCATTTCATAAATATGCTCGTCGTCATAAAAACTGCGTGTTTCTAGTTGATACGTACGATACGTTAAAATCAGGAGTTCCTAACGCCATTAAAGTAGCAAAAGAATTAGGCGATAAAATTAATTTTACAGCGATTCGCTTAGACAGCGGCGATTTAACATATTTGTCTAAAAAAGCTCGTCAAATGTTAGATGAAGCAGGGTTTACAGAGACAAAAATTGTTGCTTCTAACGATTTAGATGAAGATACGATTATGCATTTAAAGTCGCAAGGGGCACAAATAGACATGTGGGGGATTGGTACTAAGCTCATTACTGCGTATGATCAGCCCGCGCTTGGTGCAGTGTATAAACTCGTTTCTATTGAAGGAGAAAATGGCGAGATGATGGATACGATTAAAATTAGCGCAAATCCTGAAAAAGTGAGTACACCAGGATTAAAGCGCGTATATCGTATTATTAATAATTTGAATGGGAAATCTGAAGGGGATTATATCACGATGGCAGACGAAGATCCTCAAAGCGAAGAACGTTTAAAAATGTTCCATCCTGTTCATACGTTTATCAGTAAATTCGTCACAAATTTTGAAGCAAAAGAACTCCATCATGATATCTTTGTAAACGGAGAGCTTGTGTATGAAACAGAAGAACTTCAGGAAATTCAGCAGTACGTAAAAGATAATTTAGAGCTGCTTTGGGATGAATATAAGCGCACGCGCAATCCTGAAGAATATCCAGTAGATTTAAGCGAAAAATGTTGGGAAAATAAAACGCGTCAAATTGCGTACGTAAAACAAAAAGTAGCAGAAGCCCTAAATAAAAAATAGTAGGGAGCTGGAGACATGTCAAATACGCTTGCTTATTTTCAACAGCTAAACCCTGATAAAAAAATAGATAAGCTTTTAGAAAAAGGAGCGAAAATTGGTATTTATGGTTCTTCTTTTGATCCGGTTACCAATGTTCATCTTTGGACGGCATCAACGGTTGCGCATCGAAAGAAGCTAGATGCTATTATCTTTTTGCCTTCATCGCACAAACGAACAGATAAAAAGCTCCAGACGTTGGATGAGCACCGTGTAAATATGGTTAGCTTAGCGATTAAAGATAACCCCAAATTTTTGCTCGATACGTATGAGCTAGACGTATTGCCCGGCTATCATTACACATACTACACTATGGAGCACTTTAAAAAATTGCTTCCACACGCTGATTTATTTTTTATTATGGGAGCCGACTTATTGCAAGATATTGGTGAAGGCAAGTGGAAGAAAGCAGATGAACTTATTAGTAAAAACCAGTTTATCATCATGGCAAGAGAGGGAATAGACATGTTGAAAGCTATTAGTCAGTCTCCTTTGCTTCGAAATTATGACGACGGCCGGTTTCAGCTTCTTGATAAGGGGCTGGCGATGGAAATCAGCTCTACTTATATTCGTCAAGAATTTGCCCGAGGCGGAGAACCAAGATATTTAATGCCTGATCTCTGTTATTTTTATAGTAAAAAACATGGATTGTATCAGTAAGAAATCTACATATAATGAAAGGAGAGCATGTATCATGTCAGACATGCAAGAAAAAATAAGAAAAGAACTACATGTGAAATCTGAAATTGATCCAGCACAAGAAATTCGTGCCCGGGTTGATTTTCTGAAAAGCTACCTAAAGTCAGCAAATGCAAAAGGCTTTGTATTAGGTATAAGCGGAGGGCAGGACTCTAGCTTAGCTGGACGATTAGCACAGATTGCTGTAGACGAATTGCGAAAAGAAGAATATGAAGCAAAATTTGTAGCCGTTCGCTTGCCTCATGGCACGCAGCATGATGAAGCGGATGCGAAGGCGTCACTAGAATTTATTAAACCTAATGAAACATATACGTTTAATATTAAAAACACGGTGGAAGCATTTGAAAGTTCGTTTACAGGTGCGACAGATATAGCCCTGTCTGATTTTCATAAAGGAAATGTCAAAGCACGTACGCGTATGATTGTACAGTATGCAATCGGAGGAGAAAACGGCCTTTTAGTTATCGGAACCGATCATGCAGCAGAAGCAGTAACCGGCTTTTTTACGAAATACGGAGATGGCGGAGCAGACGTGCTGCCTCTAACAGGACTAACAAAACGTCAAGGAAAAGCATTGCTAAAAGAATTAGGTGCAGATAAACGATTGTATGAAAAAGTACCAACAGCTGACTTATTAGATAATAGTCCTGGTCAATCTGATGAAACGGAACTAGGAATTTCTTATGATGAACTAGACGATTATTTGGAAGGAAAAGAAGTATCACAAGAAGCCGCTGAAAAAATTGAACAGCGCTATCGTATTACTGAACATAAACGTCAGTTACCGGCTAGCATGTTTGATGAATGGTGGAAATGAGAGAAATGCCCATATTAGGTATATCTAATATGGGCATTATTTTGACTGATTTCTTTCATAAAACAAAAAAGAGGCGGAAAAAGTGCAATTTAACAAATTGTTTTCTCATACACACTTTGTTATTCTTACGCACTTTGGTATAATGAAGTGCTTTTAATATTATTGAGGAGGAACATTTTTTATGGCAGTTGAAGTAGGTAGCAAGGTACAAGGTAAAGTAACAGGTATTACTAATTTTGGAGCATTTGTAGAATTACCTGGAGGTCAAACTGGGCTTGTACATATTAGTGAGGTAGCTGACAGCTATGTAAAAGATATTAATGACCATCTTAAAGTTGGTCAAGAGATTGAAGTGAAAGTCGTTAATGAGAAAGACGGAAAAATTGGATTATCGATTAAAAAAGCAATAGATAAACCTGAAAGACCCTCATCTTCTTATTCACAACGCCCGCCACGTCAGGCAAGAAATAATGATAATCGTTCTAAGAGCAACTTCCAACCAAAGGAAAACTTCGAACAAAAAATGGCGCGTTTCTTAAAAGATAGTGAAGATAATTTATCTACACTAAAACGCAGCACTGAATCAAAACGAGGTGGCAGAGGCGGAAGACGCGGCTAAATCCCTTCCAGTTTAACTACTTTATTATATAGCTGAAGCAAGCCAATAAAAATTGGCTTGCTTCTTTTTTGTAATAGCTTAAGTGCATGCGCTAGAGGAGTAAAGAGAAGGTTAGGTACTTACTTAGTTGTAAAGTAGATGCCAATAGTGACAAGAGATGAGAGAAGATCAAGGATGAGTAGGATGAAATTTAAATCTATCATAATCATGCCTCCCTTTGTGCGAGCGTTGACGTTAGTATCTGCAAGATCTCCCTTTATTATTCTTAATTTTTTAAAATTTCATTTAATTAATTGTATATTTTATATTAAATTAAACTATGTTCTAAATAATAATTCATAAAATAAAAAGCGCTTATAAGAACAATTTTCTTAAAATAATAAAAAAACCTTATAAGTAACCGAAGAGAAAGTAGAGATGAGTCCCGGATAAAAATAGCTAAATTAACAGAAATTCGTCAGTATTCTTGTATATTCATCTAATCTCTTCATAATTTTAGGAATAAAAAAGTTACGGAAAGACGAGAAACAGACAAAATCCTTCATTTTTTGAGTATTAGTGCTTAATTTGCATGAAGATATAAAATGATTCCATAGACTCAAGGATTTTATAGTAATATATAGAACTTCCATACTATTCTAGGTTTTAGCTCACAAGCTAAGCAAAAGATTCGTATGTTCCGGGGATGAAGGCATACATAGTAGCACGAAGTATAGAGAGAAATGGAGAGGGAAAAAACAATGAAAAAAGTATCAATTCGGTCTGTATTAAGTACAGTAGCATTTTCGGTTGCTTTATCTTCTTTTGCAATGGGAGCATCCGCCAACGGAAATTCAAAACCGGCGCTTGAACCGTCTTTAGTTAAAATTCAAGGAGACTATAACTTAAAATCAGCCAAAAAAGTAAAAGTTATTGTGGAGTTAAATGAAGAGTCTGTAGCGGAAGCAAAGAAAAAAGGAGTAGCGCAAAGTAAAGGAAAGATTAAAAAAGCGCGTGACGAAGTGAAAAAAGAGCTTTCAAAAGCTTCTAAAACTTCAAAAGTAAAGCGTGAATATGACCAAGTGTTTTCGGGGTTTTCAGCGGAACTTCCGGCTAATGACCTTGAAAAAGTAGCAAGTTTACCGGGAGTAAAAGCTATTTACCCAAGCGTTGAATATCATACAACAGAAGTGAAATCGAAAGAAGTGAGCGCCGAAGAATACGGTTCTGAAATGGATAAAAGCATTTACTATGTAGGAGCAGATCAAGCGTGGAAATCAGGATATACAGGTAAAAATATGACCGTAGCCGTTATCGATACAGGCGTTGATTACGACCACCCGGATTTAAAGTCAGCGTTTGAGAAATATAAAGGATGGGATTTTGTAGATGATGACAAAGATCCTCAAGAAACGCCTGCTGAAGATCCAAAAGGCGAAGCAACAACGCACGGAACGCACGTAGCAGGAACAATTGCAGCGGACGGGAAAATTAAAGGAGTAGCTCCTGATGCTCATTTACTTGCTTATCGTGTACTAGGTCCAGGAGGAACGGGTACCACAGAAGACGTGATCGCCGGTATTGAACGTGCGGTAGAAGACGGAGCTGATGTAATGAACCTGTCGCTTGGAGATACGATTAATAATCCGGACTTGGCAACGAGTATTGCATTAGATTGGGCAATGGAAGAAGGAGTAGTTGCCGTTACGTCAAATGGAAACAGTGGACCAGCTAATTGGACAGTAGGCTCTCCGGGAACGTCTCGTGAAGCTATTTCAGTGGGTGCAACTCAGCTTCCTTACAATTTGTATAAAACGACATTAACTGTAGATAACGCAAGCTATGCTTCAGCTGAAGTAATGGGCTTTCCAAATGAAAAGGCGCTACTGGATGCAAGCGGTAAAAAGTATGAATTTGTACCTGTCGGACTCGGCAAACCAGAAGACTTTGAAGGAAAGGATGTAAAAGGAAAAGTAGCAGTTATTTCTCGCGGCGACATTGCGTTTGTAGATAAAGTTGATAATGCGAAAAAAGCTGGTGCTGTGGCAACGGTGATTTACAACAACGTAGAAGGAACAATCCCTGATATTCCAGGCACATCTTTGCCAAGTATTCGCCTATCAAAAGCCGATGGACAAGCTTTGGCAGCTTCTTTAGCAAAAGGATCCGTTACGGGCTCTTTTACAGCAACATTTGATCAGACAGTTGATGAAACAATGGCTGACTTTTCATCTCGCGGACCGGTTGTTGATACATGGATGATTAAGCCGGACATTTCGGCACCGGGAGTCGATATCATCAGCACAGTGCCAACCAATGATCCAAGCAACCCTCATGGATATGGATCAAAGCAAGGAACCAGTATGGCAGCACCCCACGTAGCAGGAGCAGCAGCGTTAATTTTACAGGCGCATCCAAATTATAAAGTAGAAGACGTAAAAGCATCTTTAATGAACACAACCGAACTGCTTCGTGACCGCAACGGGCTGGTTTATCCTCATAATACGCAAGGTGCAGGAAGCATGCGCGTAGTAGATGCAATTAAAGCAAAAACGCTTATTACACCAGGAAGTCACTCGTACGGTGTCTTTTATAAAGATAAAGGGAAACAAGTAGAAAAACAAAGCTTTAAGATTAAAAATCTATCAAATCACAGTCAAAAATACTCGGTCAAAGTAAAATTTAAGAAAAGCCATCAGGCAATTGACGTTAAATCAACAAATGATTTAGTTGTTAATGCAGGGAAAACGCAAAAAGTAAACCTGAATGTAAAAGTAGATGCAGGGAAATTATCTCCTGGCTATTACGAAGGGACAATTACCGTAAGTAACAATAAAGAAACGTACGATGTTCCAACCATCTTATTTGTAAAAGAGCCGGATTATCCTCGCGTCACTTCTGCGTATGTAGATGTACTAGGAAATGGCTCATTTGAATACGGCAGTTATTTACCAGGCGGAGCAGAGAAGCTTAGCTATTACATTTACGATGCAACGTTAGAAAAAGGGGAATTGTTAAGTTCATATACGAATGTAGAAAAAGGATTCTCTAGCGCAACGTGGGACGGAAAGATTAATGGTGAAGCTCTTCCACCGGGAACGTATTATTTATACGCAGAAGCAGTAAAAGCAGGTCAGACGACAGGTTCTTTAGGAGAATTTGAAATTAAATAA

Protein sequences of DBSCAN-SWA_2

>NC_014103|2152621:2160834|2152621_2153398_+|WP_013083025.1|DBSCAN-SWA
MSNNKAMTNQTKKEYPKPYGYTSDIAVFTIVTEEKEPYKPPKMSLKLMLIQRAMVNAEGEKNSEAGKWALPGGFVHPDESAFEAAKRELEEETGVKDIHLKHYGVYDEPGRDDRGWVITNAHYAIVPEDSLIKRKANDDAARVELFKIDEIFSLPLAFDHEIIIRDAIKEIKKDLLQTTIAQKFLPPQFTYSELQAVLLTVTDDAAIKSDQAFARKIRMLPFIEEVDGKTTTRTSKKPTKLYRFVEMNVMKPIYTARY
>NC_014103|2152621:2160834|2156241_2157063_+|WP_013083029.1|DBSCAN-SWA
MSDMQEKIRKELHVKSEIDPAQEIRARVDFLKSYLKSANAKGFVLGISGGQDSSLAGRLAQIAVDELRKEEYEAKFVAVRLPHGTQHDEADAKASLEFIKPNETYTFNIKNTVEAFESSFTGATDIALSDFHKGNVKARTRMIVQYAIGGENGLLVIGTDHAAEAVTGFFTKYGDGGADVLPLTGLTKRQGKALLKELGADKRLYEKVPTADLLDNSPGQSDETELGISYDELDDYLEGKEVSQEAAEKIEQRYRITEHKRQLPASMFDEWWK
>NC_014103|2152621:2160834|2157244_2157682_+|WP_013056909.1|DBSCAN-SWA
MAVEVGSKVQGKVTGITNFGAFVELPGGQTGLVHISEVADSYVKDINDHLKVGQEIEVKVVNEKDGKIGLSIKKAIDKPERPSSSYSQRPPRQARNNDNRSKSNFQPKENFEQKMARFLKDSEDNLSTLKRSTESKRGGRGGRRG
>NC_014103|2152621:2160834|2158422_2160834_+|WP_013083030.1|DBSCAN-SWA
MKKVSIRSVLSTVAFSVALSSFAMGASANGNSKPALEPSLVKIQGDYNLKSAKKVKVIVELNEESVAEAKKKGVAQSKGKIKKARDEVKKELSKASKTSKVKREYDQVFSGFSAELPANDLEKVASLPGVKAIYPSVEYHTTEVKSKEVSAEEYGSEMDKSIYYVGADQAWKSGYTGKNMTVAVIDTGVDYDHPDLKSAFEKYKGWDFVDDDKDPQETPAEDPKGEATTHGTHVAGTIAADGKIKGVAPDAHLLAYRVLGPGGTGTTEDVIAGIERAVEDGADVMNLSLGDTINNPDLATSIALDWAMEEGVVAVTSNGNSGPANWTVGSPGTSREAISVGATQLPYNLYKTTLTVDNASYASAEVMGFPNEKALLDASGKKYEFVPVGLGKPEDFEGKDVKGKVAVISRGDIAFVDKVDNAKKAGAVATVIYNNVEGTIPDIPGTSLPSIRLSKADGQALAASLAKGSVTGSFTATFDQTVDETMADFSSRGPVVDTWMIKPDISAPGVDIISTVPTNDPSNPHGYGSKQGTSMAAPHVAGAAALILQAHPNYKVEDVKASLMNTTELLRDRNGLVYPHNTQGAGSMRVVDAIKAKTLITPGSHSYGVFYKDKGKQVEKQSFKIKNLSNHSQKYSVKVKFKKSHQAIDVKSTNDLVVNAGKTQKVNLNVKVDAGKLSPGYYEGTITVSNNKETYDVPTILFVKEPDYPRVTSAYVDVLGNGSFEYGSYLPGGAEKLSYYIYDATLEKGELLSSYTNVEKGFSSATWDGKINGEALPPGTYYLYAEAVKAGQTTGSLGEFEIK
>NC_014103|2152621:2160834|2155526_2156207_+|WP_013083028.1|DBSCAN-SWA
MSNTLAYFQQLNPDKKIDKLLEKGAKIGIYGSSFDPVTNVHLWTASTVAHRKKLDAIIFLPSSHKRTDKKLQTLDEHRVNMVSLAIKDNPKFLLDTYELDVLPGYHYTYYTMEHFKKLLPHADLFFIMGADLLQDIGEGKWKKADELISKNQFIIMAREGIDMLKAISQSPLLRNYDDGRFQLLDKGLAMEISSTYIRQEFARGGEPRYLMPDLCYFYSKKHGLYQ
>NC_014103|2152621:2160834|2154041_2155511_+|WP_013083027.1|DBSCAN-SWA
MNMFTDDSVMLHTDLYQINMGETYWEDNIHQKKAVFEVFFRKLPFGNGYAVFAGLERIIEYIKAFKFSESDLTYLHEELGFKEDYLAYLKDLTFTGTIRCMREGELVFHNEPILRVEAPLIEAQLVETAILNIVNYQTLIATKAARIKHVVGDQVAMEFGTRRAQEMDAAIWGTRAAYIGGFSATSNVRAGKKFGIPVAGTHAHAMVQAYKDEYIAFHKYARRHKNCVFLVDTYDTLKSGVPNAIKVAKELGDKINFTAIRLDSGDLTYLSKKARQMLDEAGFTETKIVASNDLDEDTIMHLKSQGAQIDMWGIGTKLITAYDQPALGAVYKLVSIEGENGEMMDTIKISANPEKVSTPGLKRVYRIINNLNGKSEGDYITMADEDPQSEERLKMFHPVHTFISKFVTNFEAKELHHDIFVNGELVYETEELQEIQQYVKDNLELLWDEYKRTRNPEEYPVDLSEKCWENKTRQIAYVKQKVAEALNKK
>NC_014103|2152621:2160834|2153469_2154018_+|WP_013083026.1|DBSCAN-SWA
MKKALINIDYTNDFVAENGALTCGEPGQQIETFISDITRQFIEQNEYVVFAIDFHKENDSLHPESALFPPHNVEGSAGRELYGKLNDLYNVYQSQANVEWMNKTRYSAFAGTDLEIKLRERQITDVYLAGVCTDICVLHTAVDAYNKGFAIYIYEKAVASFNQKGHEWALEHFKSCLGAEII

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013083025.1|2152621_2153398_+	NUDIX hydrolase	A0A0E3JJF3	Streptomyces_phage	8.7e-10	41.9
WP_013083026.1|2153469_2154018_+	cysteine hydrolase	G3MA16	Bacillus_virus	1.4e-33	44.4
WP_013083027.1|2154041_2155511_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	1.9e-114	48.2
WP_013083028.1|2155526_2156207_+	nicotinate (nicotinamide) nucleotide adenylyltransferase	G3MA22	Bacillus_virus	1.1e-40	42.8
WP_013083029.1|2156241_2157063_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.1e-92	64.1
WP_013056909.1|2157244_2157682_+	RNA-binding protein S1	NA	NA	NA	NA
WP_013083030.1|2158422_2160834_+	S8 family serine peptidase	A0A217EQY2	Bacillus_phage	1.0e-16	35.3

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_014103|4203494:4212797|DBSCAN-SWA
ATTATATCTCTCCTTGACGAAGCAAACGAGCTAATTCTAATTCCCAGCCTTGAAATGTCCATTGCTCCTGCTCACCATTTGTTTTTTTATAGTTTTCTAAATCCAAGCCGCAGCAATCGCAACAATTCTCAAGCTCTGATTTTCCCGTTTCATCGAAATAGCCAAGCAGCACGTGACGACGGCATTCTTTTGTCTCAATAAACCCCTTCATCGCACGATACTTGTCATGTTTGTTTCGAAGACGTTTATTTACAGCCGCAACAATCGTTTCATGCAGCGATGCAGGAATTTTCCAGGGTTCAACATATTCATTTTTCACTACATTTTCTTTGTACAAATAATAACGAATAAATCGCCAATGTGTTTCTTGAACACCCACTGTATAAAGAAAGTGAGACTCTACTTGTTTTAAAGGAATGGCCTGATCATGGTTTCGTAAATACGACAAGCAGTATAAGATGGTATCTGAAGAAGGAAGCTCAATTTCAAGTAAAGAATGAGCAAAATCATCATCTCCTTCAGCATAAAGCAAGATCGCAATACTGTTTCGCTGATCGCGTCCACTTCTTCCAATTTCCTGTACATATGCTTCTAGCTGCGTAGGTGTATGAAAATGAATAACAAAGCGAACATTCGATTTGTTAACCCCCATTCCAAATGCACTTGTGCAGCAAATGATATCAAGCTGATTTTCTAAAAATTGCTGTTGAACAAGCATTCTTTCATTCGGTTCCATTCCCCCATGGTAATACTGCACTCGCTGTATCCCATTTTCCTTTAGAAGCTGTGTTAATGCTTCTGTCCAAGATCGGCTGGAACAATAGATAATTCCCGGACCTTGCAGTTCACTAACGTACATCAGTAATTTCTCTTTTTTTTCTTCAATACTTGCAACAAAATCAACTTTCATCGCAATATTACTTCGATTCATGGAATAGATGTGCTCGTTGACAGCAGGAAGTGATAAGTAGCGCTTAATATCTTCCACTACTTCCCTAGTCGCAGTTCCCGTTAGTGCCAGACATAGCGGACTGCCAAGTTCCTTCCATATATCTCCTAGCTGTAGATAATCTAAACGAAAATCATGTCCCCACTGAGAAATACAATGCGCCTCGTCCACAACGAAAAGGCCTACCTTTGCCTGCTTTAATGCTTCTACTACAACAGCATTTTGCAAAATTTCAGGAGATGCATAAATAAAACGATAAAAAGCTAAATTTTTTAGCGCTCGTTGTTTTTCTTCTTGTTGTAGGAAACTATTTAAGGCAATAACTCGCTTTTCTCCGCTTGCCTTTAGTTGTTGAACTTGATCTTCCATCAGTGAAATTAAAGGAGATACAATGAGCACCGGTCGGTTCAACAAATAAGCTGGGAGCTGATAGCACAATGATTTTCCTGTTCCTGTAGGCAGAACCGCTAACACATTATGACCGGTTAAAATATCTTGAATAATCTCTTTTTGTCCTATTCGAAATTGGCTATAGCCAAATTGTTTCTGTAGAAGTTGTTCTATCTTCACATCAAACACCACTTTTTTTAGTATCAGGTAAAATGTTTTGCTAATACGAGACGAATCTGAAAATAGGTAACGTCGTCTTTTACTTCTTCTTTTATCACCTTTAATTTATTTGTACGCAAACCTTCAAAAGCTGAGATAATTTTTTCCTGCTGCTTAGGCGATACGTATGCATCGATTGAAAAAGATGGAACAAACAGAGCTAATTCTGCAATATGATCTTCAATTGTACTTTCTTTTAAACGCCTTATATAAGCAATTTCTTCAAGCTTCTTGCCTTTTTGAAGCCAGCTATACGTTTTTAACGTCGAGCTTGTCAAAGGCAATTCTAAATATAGATCACGTAAAAAAGAAGACAGTACATGAAAGCTTTCATTATTTTTACTTACTTTTTCAATGATATGGTGAATAACCCCTAAAAGTTGAATATGAACATAATGCTCATCGAGTTCATATTGATATGCTAACTGATTTTTTGTAAAGCCTACTCTTTGGTATCCAGTCAGCTGCAAAACAAAAAGAGACGCGTCCCGTTCCGTGCAACCTTTCAAACACATTCGGAGCTCTTCGAATAGCTGGGCGGCTAACTCTTGACGCGTTTGCTTTTGAGACATAATATACGTTTTGACCCATTGAATGACCTCGGCATTTTTGGAAATGGGTAAAAACCCTTTTTGAAAATACTGTAGGTTTGATAAGGTCTGAATGAACAAAGTGATTCTTGCTAAAAATAATTGAGTACTGCTTGCGAATTTCCATCCGTCTAAAGCTGGATGAAAGGGTCGAGCCGTCAGTTCATCTTCAAGACGTGCTTGTCCCTTATCTGTCATCACATACTTTTGATTTTCAGTTTCTTCAATATACTGCTGTTCTTTTAAATATGCAACGCAGGTTTCAAAAGACCGTTTATCTAAGTAAACAAATGACTGAAAAAGAAACGAAATTCCAAAAATTTTTCCGTCTTGAATCGTTTGAGCTGACTTTTTACCTGTTAATAAATGATAAATACCATAGGCGGTTCGCTCACCTTTTAACTGTTTTATACAAAATAAAATGCTAACTTGAATATAATTCAAAGGTGTCAACTTCCTTTCTCATTCATTGTACCAAAAGTGACCAATAGCATGTGAGATAAAGGCTTTTTAGCTCTTTCCTTTATGTATCAAAACGTTTGGGCAAGTGAAGAAACCTTGATTTGATAAGCATTCTCAGTGACTTTTCTATTGAAAAGTTTTATAAATCATTTTACAATGAATAAGGAGAAATTTCACTCTTGATTCGCGAAGAGATTATATAATGAGAAATTTTCGAACACTTTACAGGAGGTCTTGTTATGCCAAAATATACAATTGTTGATAAAGATACTTGCATCGCATGCGGCGCTTGCGGAGCAGCAGCACCAGACATTTATGATTATGATGATGAAGGTATTGCATTCGTAACATTAGATGATAACCAAGGTGTAGTAGAAATTCCAGAAGATCTAGAAGATGATATGATGGATGCAATGGAAGGCTGCCCTACGGATTCAATTCGCGTAGCGGATGAAAAATTCGACGGCGATGCTAATAAATTCGAATAAGTATGGAGCAAACCTGTAGTGTACATGCTGCAGGTTTTTTTATATATAAAAATCGCTCTCCCCGGGAGAGCGATTGAATTAAACAGCAATGCGACGCGTGATCCATTGCTTCATTTTTGAAAACAATAAGACAAAGATAACCCCTGTTGCTGCTCCTTTTATTAAGTTAAACGGCAAAATACCTGCAACGATATATTGACGTGCTTGTTCACTAGACATTTCTGGCGATTGCAAGAAGATTGTATACGCTGGTAAGAAGACATAATAATTTAAGACAGCCATGAGTACCGTCATTACCACCGTACCCGTAACCAAACCTATCGTTACGCCTTTAGCCGTTTTAAATCGGTTGAACATGTATGATACAGGAAGAACGAACAGTAAACCAGCCACAAAGTTCGCCACTTGACCAACTGGAACCCCTGTAGCACTTCCTTGAATTAAATAATTCAATAAATTTTTTATTCCTTCTACTATAACAGCAGCCATCGGTCCAAATACAAGTGCTGCTACGAGTGCAGGAATTTCGCTAAAATCAATTGTTAAAAACGGAGGTAATCCAGGAATTGGAAAATTAATCATCATTAAAATATAAGCAATACTACTTAACATTCCTAGTATGACCAGCTTTTGAGTTTTCTTACTTTGTTGCATCTTGCCTCTCTCCTTCTTTGTGATCCACTCTTCAAAGAAGAAAGGTTCAACTTTATATCCCCACGCAAAAACCTCCCAACAAACGATTCGTTGAGAGGAGACATGGCAGGCATATTTAATAAACGTTCATCACATTAGGTTTTGAACGCTGAACCTCCACCTTCTCCCATCCAGACTGTACTGTCGGCTTTGGAATTTCACCAAATCTGCTCGTATGTATTACATATAAGCTCGCGGGCTCAAAACAATTTGTTTTTTACCGCCGGTCGGGAATTTCACCCTGCCCCGAAGATAGACCAATATTTAATTATGAATTTATTATATGTTATCTCGAATTAAAAGTAAATAAAGAAGTTTTTTAATTCCTATTAAATTGATGTCTTTTATAAACTTCATTACTGTTTTATATGTAAAATAAGGAAATAAGTGCATAACCAACAGCATTATGACATATTTATAGTTTCAATTTTACGTTTATAATTGTGTATTTGATAACTAATCGTAAAGTTTGAAAAATATAATTGACAGAATTTTTTTAACATGGTAAATTATCAAATATTTGATGATAGTAAAATCCAAGGGAGATGTTCACGTCATGTATAATGTATTAGTAGCTGATTCAATTAGCAATGAAGGTCTTGCTCCACTACTTGAAGCTCCTCATGTGAATCTTACGCGAAAAAAAGTTGAAGAAGTTGAGAATGATTTGCATACGTACGATGCGCTTTTAGTACGGAGTGCTACGACGGTTACAGAGGATTTGCTGGCAAAAATGCCGAATTTAAAAATTGTTGCTCGCGCTGGAGTAGGTGTCGATAATATTGATATTGAAGCCTCAACCAAACGAGGGGTTGTCGTTATTAACGCGCCGAACGGAAATACCATTTCAACGGCGGAACATACATTTGCTATGATGGCTAGCTTGTTTCGGCATATCCCCCAAGGAAATGCTTCAGTCAAAGCGCGCGAATGGAACCGCTCAGCATTTGTTGGAACAGAGCTTAATCGCAAACACCTGGGCATTATCGGATTTGGACGAATTGGCTCAGAGCTTGCCAAACGCGCAAAAGCCTTCAATATGAGCGTTCACGTTTACGATCCTTTTTTAACCTCTTCCCGAGCTGAAAAGCTAGGCGTAGAACTATTATCCCTGGATGAATTACTAGCAGCAGCGGATGTTATTACCGTGCACACTCCGCTTACCAAAGAAACAAAGGGATTGCTCAATCGGGACACGTTAGCCAAAACAAAGAAGGGTGTGTTTTTATTAAACTGCGCACGCGGCGGGATCATTGATGAAAAAGCCTTAGTTCATTATTTAGAAATTGGCCATGTTCAAGGTGCAGCTATTGACGTATTTGAAGTTGAGCCGCCGATTGATAACCCTTTGTTACATTTTGATCAAGTTATTACAACTCCCCATTTAGGAGCTTCTACAAAAGAAGCCCAGCTTAACGTTGCTGAAGACGTGGCACATGACGTTTTGCGTTTTCTAGAAGGTAATCCTGTAAGCTCATCCATTAATTTACCGACGCTTTCTAAAGAAGTTTTTGAAAAAATTCAGCCGTTTACGAGTCTTACTAAACAAATGGGAGCTGTCTTATCTCAATGCATGCGAGAACCTGTTCAGCATATCTCTATCTCTTACGGAGGTACAGTGACGGATTTGGAAACCACTTATATTACACGAAGCTTATTATCAGGCTTTTTAACTCATCGTATCGACTCACCTGTTAACGAAGTCAATGCTTCTATGATTGCCAAAGAACGAGGAATTACATTTGGCGAAAAAACATCGGAAGATACGCAAGGATATTCCAATATGATTGACGTTACCGTAACAGGCGAACAGCGTACATTTACCATTACGGGCACCTATATAGCCGGCTATGGACCTCGAATTGTTAATATTGATTCGTTTGATATTGATTTTTATCCGGAAGGACATCTTCTTTATATCCGTCATAGTGATCAGCCTGGAGTTATTGGAAATGTAGGGAAAGTACTTGGAGATTTACGTATTAACATTGCTACCATGCAAGTGGGCCGTAAGCAAAAAGGCGGAGAAGCCATTATGATGCTTACGTTTGATAAACTTTTAGATGATTCTGTCATCGCTTCGTTAAAACAAACAAGCGAAATTGTGACCATACAGCGTATTGAATTGTGACATTGAAAAAAAAGAGCCTGAGCGGCTCTTTTTTTTATGGACTTATTTTTAACACTTGTCCTGCATTTAACATCGTATTTTCTAAATGATTCCACTTTCTTAGCTGATCCATATCTACTTCATATTTGACTGCGAGCTCAGATAATGTATCTCCTTGATGGATAAGAATACAGTTATCAGAAGTCTGATGTAACTGCTGAAAAACCGTGGCAGCTAAATCGCTTTTTACGTATGCCAATAGTTTTTGCTTGTCCAATTTGGCAAGTGGGTTTACTGCATTGGTTTTATCCGGATTCCAACTTCCTTGATGAACTTCAAAATGCAAATGTGCACCTGAAGATCGCCCTGTATTGCCAACTCGTCCAATGTTTTGACCTGCGGCTACACGATTTCCTTCTGCAACAAAACGTTCCTCTAGATGAGCATAGACCGTTTCGTATCCATTTGTTTGTTTGATAAAAACAACCTGTCCATATGTATTTGAATAATAAGAGCGGCTCACCACTCCTTTTGCAACAGCATACACCTGTGTACCAACAGGTGCTGCTATATCAATTCCAAAGTGTTTGGCGTGACGTGAACCAAATATATCAGTTAAGACTCCTTCAACCGGCCACTCCCACTGCTTCTCTTCTGCTTTTACCATTTGCCCGCCCAAAAATAAAAGACCTATACACAATCCCATTACTAATACAACCAATATTCTTCTTAACACGTCAATCATGAAGAAAGAACCTCCTATGTAGATCATTGCACACAAAACATACTATATGCCAATTCTTTCTCTTTTAGACTTGTTTATAGAAAAAATAAAGAGATGTGATTCTCCACTGAATCACACCTCTTTGTTATTCTTATTATTTCAGCCGAACAAGCTGTTATTTAGCATGTGTTTACTTTGGCAGTTTGATAAAGAAAGTTGTTCCTTCATTTAATTCACTTTCAACCGCAATGATCCCTTGATGTGCCTCCACGATATTTTTGGCGATTGCAAGCCCAAGACCAGTTCCTGACTTCCCTCTCGTTCTGGCTTTATCCGCTTTATAAAATCGTTCAAATACAAATGGAAGATCTTCTTTCGGAATGCCTGCTCCTGTATCTTGAACAGAAAGATGGATTTCGGATTGACTTTTATCAAGATGCAGCTTTACTTCTCCGTAGTCATCCGTATGACGAATAGCATTATCAATTAAGTTTGTCAGCACTTGTTCCATACGGTCTGAATCAATCATCGCCTCAAATTCATCTTCTACTTTTCCATTAAGAGACAATTTAATATGTTTTTCTTTAGCTAACCCTTGAAACTTACGCAAAACACGTTCTGTAAATTCAACCATTGCTACGGATTCTAAGTGAAGCTGCACATGTCCCGCTTCCATTCGCGCCAAATCTAAAAGTTCATTTACAAGCCGGCCCATACGGAGTGATTCATCATAAATCACCTGTGCAATTTCTTTCTTTTCTTCATCCGTACTTGCAATATCGTCAATAATAGCTTCACTATAACCTTGAAGCATAGAAATAGGTGTACGCAATTCATGAGACACGTTTGCAATAAAATCTTTTCTCGATTTATCAAGTTTACGCTCTTCAGACATATCTCGTAGTACGGCTACAGCACCGCGAATTTTCGTTTGATTATAGAGCGGTGACATTAAAATGACCCACGTTTTCCCTTGAATTTTCAATTCTGCACTTCGCTCCGTTTCAGTCTCTACTACCGTTTGAAACAAATGGACAACGTTTGCTGGAAGCTCAGGCACCTGCTGATTGTTGACATCCTGCTCGTAATACCAAGTCTGAAGAAAATGCTCCGCTGGGGGGTTGGTAATTAAAATCGATCCGTCTCTACTAAACGTAATAACACCGTCTGCCATACTGCTTAAAATACTTGAAAGCTGCTCTTTTTCCTGATTAAGCGCATTGAGGTTAAACTTTAACTGCCTGCCCATTTGATTAAAAGCAATCGCTAACTCTCCAATTTCATCGTGAGTTAAAATAGGTACTTTTGTATCAAAGTTGCCTTTTGTTACTTCAAATGCCGCCTGCCTCATTTTTCTAAGGGGCGCTGTAATTCGAGTGGATAAGAAAAAAGCAAAGATAGTAGTTAAAATAATAGCAATACCTGCAGCCAATAAAATGAACTTAGTCGTATATTGAGCGGGTTCTTCAATTTCAGAAAGAGATTGATACAAATAAACGCCGCCTGTCGGTTTGTTATCTTTCATTAAAGGTACACCGACAACAAACATTAAAGGTTCATCACTCGTGTCTTTCTTTGTGGTCATGTACATTTTTTCCCGTATTACTTTACCTTTTTCAACCACTTGATTTAGCTGATCGTTTTGTTTAACAATGGCTGAAATAGCTTTCTTATTTTCTTTATCAGGATGTGTGGAATGCCAATAAAAATCTTTGTCTTGAACAATAACTACACTTGCTTGGTCTGCAAGTTCACGAGCAATGGATAGTCCTAGTTTTTCATCGTCCGTTTCCTGCACAATGGTAGAGATTTTAGCAGCCGTTTTAGTTAAACGGTTTTCTGCATCTACAACATGATAATTTTCAAAAAACTGAAGCAATAAAATAGTCAAAATAAATAAAACAAGCGTGACGAGCAATAGGATAGTAAACCATAGTTTACCAACTACACTTCTCCAAAACATCAGTTATTTTCAACCTCAAATTTATACCCTACTCCCCATACGGTTACAATCATTTTCGCCGCTTGTGACGATACACGATTTAACTTTTCACGCAAACGCTTGACGTGCGTATCTACCGTACGAAGATCTCCAAAGAAATCATAATGCCATACTTCACGCAGCAGCTGTTCTCTGTCATATACTTTATCTGGCGTTTTTGCAAGGTAGCATAATAATTCATATTCTTTTGGAGTTAAGTTAACTTCTTTTCCGTCTGCTGTAACGCGATGTGCATCATTATCAATCGTTAAGTGATCAAAGACGATAAGATTTTTCACGCTCGTTTCTGGTTGAATAAACGTTGCTTGAGAAGAACGTCGAAGCAGTGCTTTTACGCGAAGCACCACTTCTCTTGGGCTAAACGGCTTAACGATATAATCATCTGTACCTACTTCAAACCCTTGGACTCTGTTTACTTCTTCCCCTTTGGCTGTAAGCATGATAATAGGAGTTGCTTTTTTCTCCCGAATTTGTTTACAAGCCTCAATACCATCTATGCCGGGCATCATTAAATCCAATACAATCAAATCATAGTCTATGTGTAACGCTTTTTCGATTGCTTCATGCCCATCTGCTGCTTCTTCAATGATGTATCCTTCTTTTTCTAAGTACATTTTTAACAATCGTCTAATGCGATCTTCATCGTCTACTAGCAGTAATCTTTGTTCGTTTTGCAT

Protein sequences of DBSCAN-SWA_3

>NC_014103|4203494:4212797|4203494_4205012_-|WP_013084912.1|DBSCAN-SWA
MKIEQLLQKQFGYSQFRIGQKEIIQDILTGHNVLAVLPTGTGKSLCYQLPAYLLNRPVLIVSPLISLMEDQVQQLKASGEKRVIALNSFLQQEEKQRALKNLAFYRFIYASPEILQNAVVVEALKQAKVGLFVVDEAHCISQWGHDFRLDYLQLGDIWKELGSPLCLALTGTATREVVEDIKRYLSLPAVNEHIYSMNRSNIAMKVDFVASIEEKKEKLLMYVSELQGPGIIYCSSRSWTEALTQLLKENGIQRVQYYHGGMEPNERMLVQQQFLENQLDIICCTSAFGMGVNKSNVRFVIHFHTPTQLEAYVQEIGRSGRDQRNSIAILLYAEGDDDFAHSLLEIELPSSDTILYCLSYLRNHDQAIPLKQVESHFLYTVGVQETHWRFIRYYLYKENVVKNEYVEPWKIPASLHETIVAAVNKRLRNKHDKYRAMKGFIETKECRRHVLLGYFDETGKSELENCCDCCGLDLENYKKTNGEQEQWTFQGWELELARLLRQGEI
>NC_014103|4203494:4212797|4205035_4206085_-|WP_013084913.1|DBSCAN-SWA
MNYIQVSILFCIKQLKGERTAYGIYHLLTGKKSAQTIQDGKIFGISFLFQSFVYLDKRSFETCVAYLKEQQYIEETENQKYVMTDKGQARLEDELTARPFHPALDGWKFASSTQLFLARITLFIQTLSNLQYFQKGFLPISKNAEVIQWVKTYIMSQKQTRQELAAQLFEELRMCLKGCTERDASLFVLQLTGYQRVGFTKNQLAYQYELDEHYVHIQLLGVIHHIIEKVSKNNESFHVLSSFLRDLYLELPLTSSTLKTYSWLQKGKKLEEIAYIRRLKESTIEDHIAELALFVPSFSIDAYVSPKQQEKIISAFEGLRTNKLKVIKEEVKDDVTYFQIRLVLAKHFT
>NC_014103|4203494:4212797|4206342_4206591_+|WP_013084914.1|DBSCAN-SWA
MPKYTIVDKDTCIACGACGAAAPDIYDYDDEGIAFVTLDDNQGVVEIPEDLEDDMMDAMEGCPTDSIRVADEKFDGDANKFE
>NC_014103|4203494:4212797|4212080_4212797_-|WP_013084919.1|DBSCAN-SWA
MQNEQRLLLVDDEDRIRRLLKMYLEKEGYIIEEAADGHEAIEKALHIDYDLIVLDLMMPGIDGIEACKQIREKKATPIIMLTAKGEEVNRVQGFEVGTDDYIVKPFSPREVVLRVKALLRRSSQATFIQPETSVKNLIVFDHLTIDNDAHRVTADGKEVNLTPKEYELLCYLAKTPDKVYDREQLLREVWHYDFFGDLRTVDTHVKRLREKLNRVSSQAAKMIVTVWGVGYKFEVENN
>NC_014103|4203494:4212797|4206669_4207245_-|WP_013084915.1|DBSCAN-SWA
MQQSKKTQKLVILGMLSSIAYILMMINFPIPGLPPFLTIDFSEIPALVAALVFGPMAAVIVEGIKNLLNYLIQGSATGVPVGQVANFVAGLLFVLPVSYMFNRFKTAKGVTIGLVTGTVVMTVLMAVLNYYVFLPAYTIFLQSPEMSSEQARQYIVAGILPFNLIKGAATGVIFVLLFSKMKQWITRRIAV
>NC_014103|4203494:4212797|4210308_4212081_-|WP_013084918.1|DBSCAN-SWA
MFWRSVVGKLWFTILLLVTLVLFILTILLLQFFENYHVVDAENRLTKTAAKISTIVQETDDEKLGLSIARELADQASVVIVQDKDFYWHSTHPDKENKKAISAIVKQNDQLNQVVEKGKVIREKMYMTTKKDTSDEPLMFVVGVPLMKDNKPTGGVYLYQSLSEIEEPAQYTTKFILLAAGIAIILTTIFAFFLSTRITAPLRKMRQAAFEVTKGNFDTKVPILTHDEIGELAIAFNQMGRQLKFNLNALNQEKEQLSSILSSMADGVITFSRDGSILITNPPAEHFLQTWYYEQDVNNQQVPELPANVVHLFQTVVETETERSAELKIQGKTWVILMSPLYNQTKIRGAVAVLRDMSEERKLDKSRKDFIANVSHELRTPISMLQGYSEAIIDDIASTDEEKKEIAQVIYDESLRMGRLVNELLDLARMEAGHVQLHLESVAMVEFTERVLRKFQGLAKEKHIKLSLNGKVEDEFEAMIDSDRMEQVLTNLIDNAIRHTDDYGEVKLHLDKSQSEIHLSVQDTGAGIPKEDLPFVFERFYKADKARTRGKSGTGLGLAIAKNIVEAHQGIIAVESELNEGTTFFIKLPK
>NC_014103|4203494:4212797|4207840_4209415_+|WP_013084916.1|DBSCAN-SWA
MYNVLVADSISNEGLAPLLEAPHVNLTRKKVEEVENDLHTYDALLVRSATTVTEDLLAKMPNLKIVARAGVGVDNIDIEASTKRGVVVINAPNGNTISTAEHTFAMMASLFRHIPQGNASVKAREWNRSAFVGTELNRKHLGIIGFGRIGSELAKRAKAFNMSVHVYDPFLTSSRAEKLGVELLSLDELLAAADVITVHTPLTKETKGLLNRDTLAKTKKGVFLLNCARGGIIDEKALVHYLEIGHVQGAAIDVFEVEPPIDNPLLHFDQVITTPHLGASTKEAQLNVAEDVAHDVLRFLEGNPVSSSINLPTLSKEVFEKIQPFTSLTKQMGAVLSQCMREPVQHISISYGGTVTDLETTYITRSLLSGFLTHRIDSPVNEVNASMIAKERGITFGEKTSEDTQGYSNMIDVTVTGEQRTFTITGTYIAGYGPRIVNIDSFDIDFYPEGHLLYIRHSDQPGVIGNVGKVLGDLRINIATMQVGRKQKGGEAIMMLTFDKLLDDSVIASLKQTSEIVTIQRIEL
>NC_014103|4203494:4212797|4209449_4210139_-|WP_013084917.1|DBSCAN-SWA
MIDVLRRILVVLVMGLCIGLLFLGGQMVKAEEKQWEWPVEGVLTDIFGSRHAKHFGIDIAAPVGTQVYAVAKGVVSRSYYSNTYGQVVFIKQTNGYETVYAHLEERFVAEGNRVAAGQNIGRVGNTGRSSGAHLHFEVHQGSWNPDKTNAVNPLAKLDKQKLLAYVKSDLAATVFQQLHQTSDNCILIHQGDTLSELAVKYEVDMDQLRKWNHLENTMLNAGQVLKISP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013084912.1|4203494_4205012_-	ATP-dependent DNA helicase RecQ	M1PGQ0	Moumouvirus	5.1e-54	30.9
WP_013084913.1|4205035_4206085_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013084914.1|4206342_4206591_+	ferredoxin	A0A127AYY7	Bacillus_phage	3.6e-18	53.3
WP_013084915.1|4206669_4207245_-	ECF transporter S component	NA	NA	NA	NA
WP_013084916.1|4207840_4209415_+	phosphoglycerate dehydrogenase	A0A2H4PQU8	Staphylococcus_phage	1.3e-28	30.2
WP_013084917.1|4209449_4210139_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2D0ZM66	Rhodococcus_phage	4.0e-14	40.7
WP_013084918.1|4210308_4212081_-	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	7.5e-25	26.3
WP_013084919.1|4212080_4212797_-	response regulator transcription factor	W8CYM9	Bacillus_phage	4.8e-47	41.7