CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_006140	Desulfotalea psychrophila LSv54, complete genome	1 crisprs	NA	0	0	0
NC_006138	Desulfotalea psychrophila LSv54, complete genome	3 crisprs	cas8u1,cas3,csb2gr5,cas7,csa3,DEDDh,DinG,cas2,RT,Cas9_archaeal	1	2	2
NC_006139	Desulfotalea psychrophila LSv54, complete genome	1 crisprs	RT	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_006140_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006140_1

5359-5506

Orphan

Consensus_repeat	Method
AACAAGCAAAAACTCGGAGTTAACAAGCAAAAACTCGGAGTTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006140_1

>merge|NC_006140|1|5359-5506|CRISPRCasFinder
AACAAGCAAAAACTCGGAGTTAACAAGCAAAAACTCGGAGTTAGTTTTTTATTTTTTGCTCTTTTTTATAAAAAAAAGCGTCATAATAGGCAGTTAGCCCACAAACAAGCAAAACCTCGGAGTTAACAAGCAAAAACTCGGAGTTAGT

>NC_006140|1|1|5359-5506|CRISPRCasFinder
AACAAGCAAAAACTCGGAGTTAACAAGCAAAAACTCGGAGTTAGT	TTTTTATTTTTTGCTCTTTTTTATAAAAAAAAGCGTCATAATAGGCAGTTAGCCCACA
AACAAGCAAAACCTCGGAGTTAACAAGCAAAAACTCGGAGTTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_006140.1\|WP_041279091.1\|10458_10671_+\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190473.1\|10999_12466_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	unknown	unknown	gnl\|CDD\|367119
NC_006140.1\|WP_011190470.1\|9112_9481_+\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190474.1\|12503_13127_+\|DnaJ-domain-containing-protein	unknown	unknown	gnl\|CDD\|99751
NC_006140.1\|WP_011190463.1\|2285_3044_-\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190471.1\|9477_10398_+\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190466.1\|5974_6346_-\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190472.1\|10682_10988_+\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_162096688.1\|3722_5045_-\|RepB-family-plasmid-replication-initiator-protein	unknown	unknown	gnl\|CDD\|376444
NC_006140.1\|WP_011190469.1\|7906_8449_+\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190468.1\|7470_7737_-\|related-to-DNA-primase-PrmN1	unknown	unknown	gnl\|CDD\|280055
NC_006140.1\|WP_011190464.1\|3160_3691_-\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190462.1\|1829_2285_+\|hypothetical-protein	unknown	unknown	unknown
NC_006140.1\|WP_011190461.1\|295_1435_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|377306
NC_006140.1\|WP_083819028.1\|6843_7134_-\|toprim-domain-containing-protein	unknown	unknown	gnl\|CDD\|379044

Protein	Function_ID	Function_description	E-value
NC_006140.1\|WP_011190473.1\|10999_12466_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	gnl\|CDD\|367119	pfam02534, T4SS-DNA_transf, Type IV secretory system Conjugative DNA transfer. These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerisation domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.	3.32471e-46
NC_006140.1\|WP_162096688.1\|3722_5045_-\|RepB-family-plasmid-replication-initiator-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	1.78308e-28
NC_006140.1\|WP_011190474.1\|12503_13127_+\|DnaJ-domain-containing-protein	gnl\|CDD\|99751	cd06257, DnaJ, DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.	2.86023e-07
NC_006140.1\|WP_011190468.1\|7470_7737_-\|related-to-DNA-primase-PrmN1	gnl\|CDD\|280055	pfam01807, zf-CHC2, CHC2 zinc finger. This domain is principally involved in DNA binding in DNA primases.	5.61719e-10
NC_006140.1\|WP_011190461.1\|295_1435_-\|ATP-binding-protein	gnl\|CDD\|377306	pfam04326, AlbA_2, Putative DNA-binding domain. This family belongs to the AlbA clan of DNA-binding domains.	3.73814e-11
NC_006140.1\|WP_083819028.1\|6843_7134_-\|toprim-domain-containing-protein	gnl\|CDD\|379044	pfam13155, Toprim_2, Toprim-like. This is a family or Toprim-like proteins.	2.46968e-07

>NC_006140.1|WP_162096688.1|3722_5045_-|RepB-family-plasmid-replication-initiator-protein
MVHLPEVYNPHTLVRKSTKMLSKNYCFTEREGKFIDLMIAVSDGNAEDFDSLRFSISQLAEYYKIKPDGAYKAIQEITAGLITKGFQLTTTSEEGAIIVSQSSFLCQADYNKGKGTVDVRFSPIMKKYLLSASLKSYIAYPIGMRNEVVGGNVWRFYEIIRLYSFLGKKTLVIDELKVLMGLTSKYKQPTDFIKYVIEKAMVEIPLKTEMYFSYKTRKLGRKTHFLDLIIIDKDAQAILKMKFNSVSPEHYRDLIGYGISPKKILSMDKSGILDESRVVRNIEYTLSEDEKGKVDTIAAFISSAITGDWAKKSPYKKKKETREKEKDEKDKKSIEEIKAYQKRKDKEKILDEEYSLYCNSQFEKYLDKNIEKFTKQFLDNCHDGIKSTILRKISSLKTIDEYYKTVIFEVQAKLYYRKNILDSSVNTFEKWLLKTKGIKF
>NC_006140.1|WP_011190464.1|3160_3691_-|hypothetical-protein
MSKNEIVEQKGTGEIFTAEELPFPIKLMLDIYNLSTTSENIKKEITLHLNDLATKRNHKASGFRKDENGRLIFDDKLFTESIYKGKIDTYTNVLKNRANKLLKDMEMVQHMGESHSAISMIIDKQLLEQKVCEEISRKAQDQERILKMIPQIFPELKRNAIFINDKKDVKKLNEPK
>NC_006140.1|WP_011190463.1|2285_3044_-|hypothetical-protein
MKIYQTMHKAIAVRLVKKAHCTSGIRRTSPYSRFSTILNHKKGGGSYVVDKFDANNFSCRSFDGTSWTDDFNITVENLSQYYLYTTYYFEPNFFFKPKETKSLFKIYLLYFTRYPYWFNKIYGILCTKFAYLHLNKEASASERNQLLQFLVRQQVNNGKQKIECDYILQKFYRSHRLGSTGSKLQKKKMDFYLESLKDCKDIQKYETTIKVSGKAINTIDEFNSQKTKSRISMGFQLLTVILAFVTAYLALH
>NC_006140.1|WP_011190462.1|1829_2285_+|hypothetical-protein
MINRLIKKTLITGILLVAVTAVTIYFVYDPGIFKKWPWFRYSLSLSVLTILSAFTYMAWCMLDVIRWDNLFHRGSLGSDFSAVGYGGVIAPILVLLLYPSLSSLGVHSDGSVRTVGFVMAFTHGIGFGYIQTQINNTITEIYKARSEEETL
>NC_006140.1|WP_011190461.1|295_1435_-|ATP-binding-protein
MNLQELKVNVTDIISDLKNNGNFPKENSHIDYKVDLKLTKSKSSLENFLLNFAKDIISFSNADGGMILLGIKEDKTTGKNDDVGLPSETLEILEQIDLNDVTQKFEKIAKVGVSIDLQKFKISTRLFYYLIIEKNNQILIPQADVPEYKLQKGAIYYRASSKNEHANQSTADFNRFLQIKANERSKEFMEIWSKLLPEMVDINPREVLILNPVQNRVYGFNSRDNILSNSDVEIDKNQNGVFNIILNAISAGEIGKITTNEGKPIYKIVGELSNFKEHITMTSLNKAVKDKVIYNFGNQHLKIAMRYLGWVDDPKFKVNNPPEGTVDNKFEHYIWVESLDNYSKTTKVFFSVGAADEMARVINNESIHKEIFNKLLIKK
>NC_006140.1|WP_011190466.1|5974_6346_-|hypothetical-protein
MEFEWFEEQIKRGAKRNANPTVTISKNGGINFNKKALEEYNINESIYIIYGISEDKTSIGFNFVAEKKAGAYKINIKENGASASIKRFLEHKNIVISSSTKFPLHQENDFVCITLTEGETSKK
>NC_006140.1|WP_083819028.1|6843_7134_-|toprim-domain-containing-protein
MDFLSFLTDKKESVLEYVNSVIIMCSVSMAKKTIEKIFCICLETNIKSIYTLLDNDKTGKKTTKFFKDNLKNLVVDDKSYIYAKFNDYNDFLQKRK
>NC_006140.1|WP_011190468.1|7470_7737_-|related-to-DNA-primase-PrmN1
MKCEQAKNIKLDLVLNKLGYAPQKYLNSQNSIKYFSPFREEKTPSFDYSPLKNAWFDHGTGEGGNTLDFIIGFQKCSVSQALNFLENI
>NC_006140.1|WP_011190469.1|7906_8449_+|hypothetical-protein
MRFNTLMVCFFSSVCFFLVLPFNASAEDLLNIRQYTNKNKPETLGEFTIEKEKETNLAYITSATNKASFLLFEKEIKRPFEIKFQKYSLENFAINIISEKKEIKISYNQWLYVNKKRVEDCSLRIARWNTLRIKVKEDKLVFYINGEKSYTLPSVDNNIVEEILFKFGDTTKISKLEIKK
>NC_006140.1|WP_011190470.1|9112_9481_+|hypothetical-protein
MSRKKYLQEYQKEYRKEKKQVTLTLTLTEYNYFKTIADKEDIKVTSLIKAMALSQLGKTFYFPKEILKRIDEFIFIIRNIANNLNQIARHSNIIKNVINENSVLSLIKNLETEVKRFIKSKI
>NC_006140.1|WP_011190471.1|9477_10398_+|hypothetical-protein
MIIKSLSRKKPTFGQLSDYIYNEADKEYIYTYNMYSDKNKLKDIKKEFKENYSFLKKQKNSNALYHEMLSIKKSNIEIDLQKKALYDIVNEYIKVRSPNCLVYGGLHEAENNLHYHVIISSNQIEKEKNNYLSKKEFSEIKKGLEMYVLNKYPELKQEIIINKEKKKNTISDKEYQLGKRTGRQTKSENLKERLNNIFNNAKTKKEFFDALYWEKIEIQLKGKTIKFIDEKTGLTRRLKRLGLEEEFYKLSDSLEQQEAKYQEGKQTHEQQQAHEQQQAHEQQEQTKNTESAEELKKNKEIKEKNF
>NC_006140.1|WP_041279091.1|10458_10671_+|hypothetical-protein
MGFLSFLDSFMSLISILDNKNDVSDDKEDTNKSETKPVNESKKNELIAERKSEFSKVEKKEKEKDKSRQR
>NC_006140.1|WP_011190472.1|10682_10988_+|hypothetical-protein
MIDFLGLFDGFMSFFSLTKDSSTKIDNGNNRCGNCKKNNYKKPTYEAKTIDKKQKNDLLEKQKNARIKREMDIVKRKADFYSTKQPNMTIKDNVVTYDFKN
>NC_006140.1|WP_011190473.1|10999_12466_+|type-IV-secretory-system-conjugative-DNA-transfer-family-protein
MSKLIADTLKTFFNVGKFIAKGYVLKKEEGARFAKNSEQNEIINSSNRGLLINGINKRLSEKESFKHIAIIAKSGIGKTTGYIYPNIFDKADSNCSMLITDPSSEIYETTSQHLKNRGFKIVRLNPSNINQSSRFNPFHGLGAEDIIEIEQICTSIIKSKYGNDKEQVWNDGAISLLELFAKCLAYTQPEYLNLPNLNYLIQMFGESGENLDDWVIEHSINPYDEQDRSILDFWIGLRSNNANMLTSYATIVKTALKQLNNRKIQRLLSNNDIDLEDFRKQKTAIFLSFPDNQQDYYQFLVDIFYARFFSVMMSKKPTPRDLNVYCFLDEFGNAYVDNFPTIVTTIRKYRVSLSVVLQGISQLNKKYGDMAKSGISSFIIYAGGDYETLNEQSQLIGKKRIIQRNKFEDHVTSYQDIDLLPPAELRTMKDNQALFLSSNKYPFIFEFQPFYKNRKFLTLSKKGEYIPLEKQKDMCWNQLFLKKNNKNK
>NC_006140.1|WP_011190474.1|12503_13127_+|DnaJ-domain-containing-protein
MALNVFDSVLLSFVYALITWVCFYSIKKLHWLLKIVPIIFLTSVIGHSPSFGARIMIISFLIMVARELYIKNNCYFLYEIFSNATDFLKNKKNKRKEEENFNSERKSNNENIKEELSQAKERLKKVREEADHQKANHQKAASKPPRERLNIFSEPLTHAELKKAYRLASLKCHPDHVEHLSETLKETANEEFKKLNEAYNKLKKVAQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

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CRISPR-Cas detection and classification

Crispr_ID: NC_006138_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006138_1

52251-52334

Orphan

Consensus_repeat	Method
GGAGGACACTGATCCCTTTTAGGTAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006138_1

>merge|NC_006138|1|52251-52334|CRISPRCasFinder
GGAGGACACTGATCCCTTTTAGGTAAAGGACAGGGATTAAAAGTTAACCACTGCTCTGGAGTACACTGATCCCTTTTAGGTAAA

>NC_006138|1|1|52251-52334|CRISPRCasFinder
GGAGGACACTGATCCCTTTTAGGTAAA	GGACAGGGATTAAAAGTTAACCACTGCTCT
GGAGTACACTGATCCCTTTTAGGTAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_006138.1\|WP_041277417.1\|41333_42305_-\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_011187288.1\|43004_44111_-\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl\|CDD\|99740
NC_006138.1\|WP_041277421.1\|59811_60054_+\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_041278136.1\|61758_63165_+\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|273050
NC_006138.1\|WP_041278134.1\|44988_46047_-\|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|236649
NC_006138.1\|WP_011187291.1\|46063_47101_-\|Vi-polysaccharide-biosynthesis-UDP-N-acetylglucosaminuronic-acid-C-4-epimerase-TviC	unknown	unknown	gnl\|CDD\|185103
NC_006138.1\|WP_011187285.1\|40809_41337_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NC_006138.1\|WP_011187306.1\|64309_66958_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341408
NC_006138.1\|WP_041277419.1\|55061_56366_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182422
NC_006138.1\|WP_041277420.1\|56885_58430_-\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_041277418.1\|53138_54206_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226288
NC_006138.1\|WP_011187292.1\|47109_48390_-\|Vi-polysaccharide-biosynthesis-UDP-N-acetylglucosamine-C-6-dehydrogenase-TviB	unknown	unknown	gnl\|CDD\|185104
NC_006138.1\|WP_011187287.1\|42312_43002_-\|WbqC-family-protein	unknown	unknown	gnl\|CDD\|378083
NC_006138.1\|WP_041277422.1\|63370_63565_+\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|376472
NC_006138.1\|WP_156792160.1\|48435_50436_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NC_006138.1\|WP_041278135.1\|51226_51598_-\|GxxExxY-protein	unknown	unknown	gnl\|CDD\|372581
NC_006138.1\|WP_011187303.1\|60667_61636_-\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NC_006138.1\|WP_011187289.1\|44107_44989_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NC_006138.1\|WP_011187298.1\|58966_59845_+\|deoxyribonuclease-IV	unknown	unknown	gnl\|CDD\|179214
NC_006138.1\|WP_041277423.1\|67021_67654_+\|site-2-protease-family-protein	unknown	unknown	gnl\|CDD\|100079

Protein	Function_ID	Function_description	E-value
NC_006138.1\|WP_041278136.1\|61758_63165_+\|FAD-binding-protein	gnl\|CDD\|273050	TIGR00387, Glycolate_oxidase_subunit_glcD., glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other].	7.83999e-150
NC_006138.1\|WP_011187288.1\|43004_44111_-\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl\|CDD\|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	5.52853e-141
NC_006138.1\|WP_041278134.1\|44988_46047_-\|dTDP-glucose-4,6-dehydratase	gnl\|CDD\|236649	PRK10084, PRK10084, dTDP-glucose 4,6 dehydratase; Provisional.	0
NC_006138.1\|WP_011187291.1\|46063_47101_-\|Vi-polysaccharide-biosynthesis-UDP-N-acetylglucosaminuronic-acid-C-4-epimerase-TviC	gnl\|CDD\|185103	PRK15181, PRK15181, Vi polysaccharide biosynthesis UDP-N-acetylglucosaminuronic acid C-4 epimerase TviC.	2.65336e-161
NC_006138.1\|WP_011187285.1\|40809_41337_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	3.8084e-26
NC_006138.1\|WP_011187306.1\|64309_66958_+\|CBS-domain-containing-protein	gnl\|CDD\|341408	cd17772, CBS_pair_DHH_polyA_Pol_assoc, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the DHH and nucleotidyltransferase (NT) domains. This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with an upstream DHH domain which performs a phosphoesterase function and a downstream nucleotidyltransferase (NT) domain of family X DNA polymerases. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	2.05529e-55
NC_006138.1\|WP_041277419.1\|55061_56366_-\|hypothetical-protein	gnl\|CDD\|182422	PRK10381, PRK10381, LPS O-antigen length regulator; Provisional.	1.59043e-06
NC_006138.1\|WP_041277422.1\|63370_63565_+\|30S-ribosomal-protein-S21	gnl\|CDD\|376472	pfam01165, Ribosomal_S21, Ribosomal protein S21.	3.41567e-06
NC_006138.1\|WP_041277418.1\|53138_54206_-\|hypothetical-protein	gnl\|CDD\|226288	COG3765, WzzB, Chain length determinant protein [Cell envelope biogenesis, outer membrane].	9.40897e-09
NC_006138.1\|WP_011187292.1\|47109_48390_-\|Vi-polysaccharide-biosynthesis-UDP-N-acetylglucosamine-C-6-dehydrogenase-TviB	gnl\|CDD\|185104	PRK15182, PRK15182, Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB.	0
NC_006138.1\|WP_011187287.1\|42312_43002_-\|WbqC-family-protein	gnl\|CDD\|378083	pfam08889, WbqC, WbqC-like protein family. This family of proteins are functionally uncharacterized. However it is found in an O-antigen gene cluster in E. coli and other bacteria suggesting a role in O-antigen production. Feng et al. suggest that wbnG may code for a glycine transferase.	3.48218e-89
NC_006138.1\|WP_156792160.1\|48435_50436_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NC_006138.1\|WP_041278135.1\|51226_51598_-\|GxxExxY-protein	gnl\|CDD\|372581	pfam13366, PDDEXK_3, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	4.3522e-56
NC_006138.1\|WP_011187303.1\|60667_61636_-\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	4.35569e-128
NC_006138.1\|WP_011187289.1\|44107_44989_-\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NC_006138.1\|WP_011187298.1\|58966_59845_+\|deoxyribonuclease-IV	gnl\|CDD\|179214	PRK01060, PRK01060, endonuclease IV; Provisional.	7.04077e-172
NC_006138.1\|WP_041277423.1\|67021_67654_+\|site-2-protease-family-protein	gnl\|CDD\|100079	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with a minimal core protein and no PDZ domains.	9.35135e-69

>NC_006138.1|WP_041278135.1|51226_51598_-|GxxExxY-protein
MDSKELTGAVIGCAIEVHRQLGPGLLESSYERCLLYELQCLNIFVRTQVVLPIRYKDIEIDAGYRIDLLVADELIVELKVVDTLLPLHTAQVLTYMKLAGVDTGLLINFNVLRLVDGVRRLVL
>NC_006138.1|WP_156792160.1|48435_50436_-|polysaccharide-biosynthesis-protein
MKKILGIAVFLRHQFLLLRRRFSQRNAWFLVLADCLSIVLAHFLAHLIRFDFQQQPGDVSHFLVFIPFIFLVRLPIFYAFGLYSGMWRYTSFRDLLNIIKAVLTSSLTIVGILFLLDTSMQFSRSVLVLDAILTFLLVCGVRVGIRFILRHVVDKTGRRAYFNSCKKLLIVGAGSAAEKTVREIRENSKLCYDIVGFVDDDPSKRGLRIHNIPIWGGVDFVGECAQQTKAEELLIAIASLTGEEMQRIASLCQKTGLPYKIIPSFGEIIDGHANLSDIRDISYRDLLGRAEIKLETDEIGSCLAGKNILITGGGGSIGSELVRQVTTFAPAKIIIFEACEENLYNIQMELLHEYDLDNIVPVLGKVQDHKLLINVFEQHKPQVIFHAAAYKHVPLVENNAWQAVDNNIVSSQLLMEAAIVYGVERFVVVSTDKAVRPTNVMGASKRMTELLMSAYRKRNWQGNLSPIWQRIIKDRSIEHNTIFMAVRFGNVLGSSGSVIPLFTRQIQRGGPVTVTHPKITRYFMSIEEAAQLILQAASMGEGGEIFLLKMGKPVLIADLARNLIALAGLVPDQDIKIEYSGLREGEKLYEELITEGEGIVETGHDKIMVLAGEKVLTDSEAIAIVMELRQEARAFDGDRVRDLLKVLMPEYAEMVKVNEALVKVAL
>NC_006138.1|WP_011187292.1|47109_48390_-|Vi-polysaccharide-biosynthesis-UDP-N-acetylglucosamine-C-6-dehydrogenase-TviB
MEYSLDTTKIGIVGLGYVGLPLAVEFGKKISTIGFDLNESRVRDLVAGSDFTLECSAEELSKASELQYSTNLEDLRDCNVYIVTVPTPIDEHKCPDLSPLVKASESLGQVLSKGDIVIYESTVYPGATEENCVPVLERVSGLSYNKDFFAGYSPERINPGDKEHSVTMIKKVTSGSTEQIADFVDELYSSIIIAGTHKASSIRVAEAAKVIENTQRDLNIALINELAIIFNKLGIDTEEVLEAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAQSVGYHPEVILSGRRINDNMGSYVASQLVKALIKKRIQVEGANVLLLGLTFKENCPDLRNTKVVDIISELAQYNIQVDVYDPWVSKIEAEKEYGISPVEKPGQNKYDAVVVAVAHNEFVALGESGLQDLLREKSVVYDLKYILPRAVVDIRL
>NC_006138.1|WP_011187291.1|46063_47101_-|Vi-polysaccharide-biosynthesis-UDP-N-acetylglucosaminuronic-acid-C-4-epimerase-TviC
MTRYQEVQQELKDSPKTWLITGVAGFIGSNLLETLLGLGQKVVGLDNFVTGYQHNLDEVEGAVTDAQWQNFRFIEGDICSLDACQEACQGVDYVLQQAALGSVPRSIVDPITTNNTNISGFLNMLVAARDAEVKSFTYAASSSTYGDHPALPKVEENIGNPLSPYAVTKYVNELYASVFARTYSFKTIGLRYFNILGKRQDPNGAYAAVIPLWTAAMINDETVFINGDGETSRDFCFIENAVQANILAATATEEARDNVYNVAVGDRTTLNELFNLIKHNLADHGIVYNLDPSYRDFRAGDVRHSQADTTKIKRLLGYSPQYKIGAGIEKAMGWYVQSLSVSGHK
>NC_006138.1|WP_041278134.1|44988_46047_-|dTDP-glucose-4,6-dehydratase
MKILVTGGAGFIGSAVIRHILENTDDSVVNLDKLTYAGNLESLEGVAGNEHYLFEQVDICDREELVRVFAIHQPDAVMHLAAESHVDRSIDGPATFVETNIVGTSTILQVAQKYWSALPEERRECFRFHHVSTDEVYGDLADPEEFFTEETSYAPSSPYSASKAASDHLVRAWQRTYGFPTIITNCSNNYGPYQFPEKLIPLMILNALEGKALPIYGNGQQIRDWLHVEDHARALLLVLRQGKIGETYNIGGHNEKSNLEVVHTLCDVLQEMVPGEEGSSYRDLISHVADRPGHDLRYAIDAGKIERELGWRPQETFESGIRKTVQWYLDNKGWWSRVLDGSYNRQRLGVRA
>NC_006138.1|WP_011187289.1|44107_44989_-|glucose-1-phosphate-thymidylyltransferase-RfbA
MKGIILAGGSGTRLYPITMGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDLASFQRLLGDGSQFGVDLSYVVQPSPDGLAQAFILGEEFIGDDDVCLILGDNVYYGQGFSPMLQQAVVTAQSGRGATVFAYQVKDPARFGIVEFDEERRVRSIEEKPAQPKSNYAVTGLYFYDNRVVKIAKEVKPSSRGELEITSVNNAYLALNDLNVQLLGRGFAWLDTGTHESLLEAAQFVETIEKRQGYKVACLEEIAYNNGWLSIESVREVGQRLSKGCYGKYLLTLIAEAK
>NC_006138.1|WP_011187288.1|43004_44111_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MKEKNIYVTQPFLPPLEEFTPLLKEIWESKILSNCGPMHQRFEQALCDYLGVEHICLFNNGTIALITALQALGITGEVITTPYSFVATANSIVWNGLKPVFVDIDSETLNLDPAKVEAAITPATTAIMPVHCYGNPCDVKAINEIAQRHKLKVIYDAAHAFAVQDKGGSILRHGDLSVLSFHATKVFNTFEGGAIVCKNAEIKQRIDQLKNFGFVDETTVALAGINGKMSEVNGAFGLVQLNYIDEAIKQRSLVDEYYREQLRDVKGITVPSSSALKQNYSYFPVLVEEEYPLTRDVLYQKLKDNNIYARRYFYPLMSDFPMYRGEPSSKKENLSVATEVASKVLCLPIYPTLDLNGLQRVVSFFKKV
>NC_006138.1|WP_011187287.1|42312_43002_-|WbqC-family-protein
MVIAVMQPYLFPYFGYYQLVNCADKFVVYDDVNYIKGGYINRNNILVKGQSQRFTVPVPGASSNKKIKELSFSSDVKKVLSTIQQSYSKALFFNEIFPIVEAILTYEDRSLAEVCKQSLSQVFAYLGVEKEIIKSSELDYDHSLSAADRLIDITRRFGANKYINSIGGQSLYNKDYFQSNGIELSFIKMDEVSYTQANNKFVPYLSMIDVLMWCKKERVVEMLKSYKMV
>NC_006138.1|WP_041277417.1|41333_42305_-|hypothetical-protein
MNSEAIGGYFELELPVAKQSLYPQALRYQSARSAFYALILYVNPRRIWMPLYICDAMLAPVHKAGVEVSFYSLNDDFSIKEDLKLQENDLLLYVNYFGVCGKQQLKILEKYNSDQIVFDHSQAFFQAPLDCLATIYSPRKFFGVPDGGFLVTNVSMVEPEEIDEDSIKRSIHLLKRLADSAEFGYLDYQLAEKTLMDFVPKKMSKLTERLLSVVDYDAVRTARNENFLYIHSILGGSNKININLSFVDGPMVYPFLYAQEGLKDILIKSRVFISTYWAECIDKVEDGCFEQKLVNMLVPLPCDQRYALEEIRIILSVMNRIGI
>NC_006138.1|WP_011187285.1|40809_41337_-|GNAT-family-N-acetyltransferase
MRDFYLREISRQDQKTINEWRNNNDLISLLGAPFRYIDESIDSAWLDNYFSNRSNCVRLAVCQHGSNDIIGAVYLLSIDWISRSCEFAIWIGDVEFRGNGVGTFATEGALKHAFLDLNLNRVYLTVLEENEAARALYKKVGFSEEGKHRQAVFKEGKYMNMIQMSILKNEFSLSN
>NC_006138.1|WP_041277418.1|53138_54206_-|hypothetical-protein
MSEARPVGSSIQAPNLCPLSVSNYRDDEIDLLSLLVDVWQQRWFIGGAVSVIGALALVLLLALPSTYEVTAEIEIPSAVSSPLLPALYQQIDTLENLENVPSEMIGEDGNMELPFVLRTPSVGSNPLLAQHRFNRVYQLLKSRDMWLAYQKKTGKTFSAEQGLQAELGRFKGALSVTVLAPQGKKNQSITNPTVLGISLRGGGDEKLARELEGFLQFVNERVVTEVSGGQQIILKGYRDSVENQISLIQLQNQVGPMKDSTAGKGQDAGVASMPATAGLAYGLTQLQSSLQQLQNFSPDLAGLKGFQYLSHPLGEGEKIKPKKALILAATLLFAGFLAIVLALLRTALQRRKEAM
>NC_006138.1|WP_041277419.1|55061_56366_-|hypothetical-protein
MQEDKTALLAREFRGRDKEQSPYFQNDEIDLLGLLHDIWDQRKFLMKIVLAVTLVAFLVLLVLPSTYQARMDIGQADSVALVVPVATGQDLLTRSYRFGIVSQYLKSFDSWVTFRQGNREGAFTDEELQGLQGEFVGLSVQVQAPKPIKGKAVSDPSVLRISYRGGGDNTSVEQRLTGFVLFVDKKAAAYVEQEMEVVIQKAGKEINNKIGLLRHAASVDRGNRITRLLAQQKKDLEQVDMEISALKASVLRSRAVRLTRLQENYAIAESLGIKLPTSMDNISERNVSNLKVMVTDQTAMPVYLLGTEVLAKRIQILREISDKKLYAQQLQPLLEKRELLLGSSELNGLRARKDDDAYIAELPGLLSRLQQLDAYTDDLQGVHALQVYSAATGSGHKIKPKKALILATTVLLSCFLAVALALLRTALQRRRESM
>NC_006138.1|WP_041277420.1|56885_58430_-|hypothetical-protein
MDQSKALDVVRHADDDCIDLTTIFRDLWSCRRWITIAIACLFFLMASSAAFLLSKKEMRVVDLPVHFSFAGAASGEYPNGMSFKVRDLLETPILRAVYEEKQLAEYLSFKDFQASLTVLKDSRGMLILEQRFLAATASKKMSSEQWGVLHKEYLADKRSLMASAPYFLRMAGDAIPYDIAEIVLTQLLEGWANYSKESKGIFQYSIPIISSSAILRDMSESEFMIIADRYRLVLQRVEGFAKGVEALPGADLLRGDRGTIADLQSEIKDIQLFAFKNLFAKIWGLGVFKEKNQALLYIDYRLDALNRKRVEIEKRIRVVEDAMEAYIQNRATRSSRSGAGGNSSLSASGGSMIPQIGDAFLDRLVKLTNESAEAQFRQGLMKRIIAEGTDLAGVESDISFYQNMKNTPENDLAKRLSADEKFAIVNGDILQIQENLVAVVEGVSTIYKEVCQLYLKPSQTMYTIVGPVQKRQAGVYEAKKIILLEVAFGMLALGMIFIAALLFSALRRRGQSFK
>NC_006138.1|WP_011187298.1|58966_59845_+|deoxyribonuclease-IV
MKYIGAHVSAAGGVENAPKNAVAIGANAFALFTKNQRQWKAKPLTEESIAAFKENLTEAGIEARHVLPHDSYLINLGHPEAEALEKSRGAFMDELGRCAQLGLPLLNFHPGSHLKKIDPEACLDRIAESINLAHGSVADVITVIENTAGQGTNLGYRFEHLARIIAAVEDKSRVGVCIDTCHAFAAGYDLRTVEACEKSWAEFDRIVGFKYLRGMHLNDAKSEFFSRVDRHQSLGAGNIGWEAFRYIMKDDRFDDIPLILETVDTSLWQEEIKKLQQWSVVEWRELEKTKTS
>NC_006138.1|WP_041277421.1|59811_60054_+|hypothetical-protein
MARTRKNKDKLTTEEEEYTEKNSLIKKQKTLKIKQLGKEKCSPPSVAHPKPSVFFSQWLTLFVFKQLAVHQKTSVFSVVM
>NC_006138.1|WP_011187303.1|60667_61636_-|D-alanine--D-alanine-ligase
MQEQRAERLRIALIAGGTSGEREVSLTGADGVERILDKEKYLVSRYDSATDLPRLAADAASIDFAFILLHGLHGEDGTIQGFLDLLGIPYQGSGVLGSALAMDKDLAKEFYYNAELPVADWHTIAAGDFFYSEELIEDLGLPLVVKPACAGSSIGISLAHTEEELLAGINHARDCSAGAIMVEQFIKGRELTCAVLGNDDLQALPVLEIVPGDKYAFFDYEAKYQPGASEEICPALIADALREQVQDHAIRAHQALRLRGYSRTDFIYGEDGKLYLLETNTIPGMTETSILPQEAAATGMDFPSLLDTLIELGLEKSKGKKG
>NC_006138.1|WP_041278136.1|61758_63165_+|FAD-binding-protein
MTSLNSNIIKKISAIVGKEYCTTRMADLHCYSYDGKGIIYLPEAVAFPRTTEEVSEIMKLASLHRFAVVPRGAGTGMTGGSLPIAGGLVMAMTRMNSIVEIDHRNQVAVVEPGVITIDLQKAVQAVGLFYPPDPASLKFCTVGGNAAECAGGPSAVKYGVTKDYIMGLEAVLPSGEIVTAGTRTEKGVTGYDLTRLFVGSEGTLGIITKLYCRLLPLPESKATFLVLSKSLDKATELVSTILNRGIVPSTLEYMDRTAIRIVSDLLSEPPAKGTEALLLLELDGTQKSIDEQTVRLRQLLADDDDISFRQAKNEAEVKELWLARRSISPAAFKLKPHKISEDVAVPRSRIPELVRFTEKLSQELDITILTFGHAGDGNIHVNIMIDKANANELERGEKAKELLFVHTISLEGTLSGEHGIGITKSAYLGLELNEATIKLMKSIKSVMDPHNILNPGKIFPETIESGDK
>NC_006138.1|WP_041277422.1|63370_63565_+|30S-ribosomal-protein-S21
MIEVEVRGDLEYAIRQLKKKLQIDGIKRELKRREYYEKPSVKKRRKQAEARRKLRKFNRMKKSY
>NC_006138.1|WP_011187306.1|64309_66958_+|CBS-domain-containing-protein
MHIITTHQNADFDGLASMIAAQKLYPSAILVFPGSREESLHEFIAQNISCNYDFQTADSIELADVRRLTIVDCQSSDKIGRIAECLQNQDLRLDIYDHHSQGRGDLRGDSDHNRIYGACTTVFTRLFQEQKTSISPEEATIFALGIYGNTQSMTRSQTRAEDLYAAGWLVAQGAKLHVISHFLGGALGIAQDEILHELKQEADLFTIKKFPVTIASLSRPQYINDFGLIVKRFYEMENLDAIFVLLATENRIHLTAISRITDIDVGLIAREMGGGGYASTASATLIGLSMNEVEEKLIALLHRHIQPQPLALEMMTRPVITISPEISIAEANTTLTRYNITAVPAIRDGKVAGIISRQVVEKALYHDLGHLPVKSYMSTEVQSLGPDAELAEVQELIVEQRQRLVPILEQGELIGVVTRTDLLRKLVTSPENLPNDRQSGSKMPLPTKRKNLNNLIHETLSPEIITLLQEVGELADEIGFKAFAVGGFVRDLLLKTANLDLDIVVEGNGIAFAKKVAEHFKGKFFPHEKFLTATVTLPNDFKIDIATARLEYYESPAAMPMIQLSSIKLDLSRRDFSINAMALQINREQFGTLIDYFNSQSDLRNQVIRVLHNLSFVEDPSRIFRAIRFEKRMNFHIGPHTKGLIGNAVAMNLFGKSRDSRFLSELKIIFKEKDPLGPLVRLAEFGLFQYLWPDLRPNYRTDRRFCHGIRQTKAAIKKLYEIEPKAKIDKSVAFLLTIFHRSGPEEIQAFCNRFNEEEKICKKLLQTKQRCDALLPILYTPMAKSELHQHLQDLNYEDLLYICSVAKKSHIHKSVLDYLCQLRHIKPLLKGKDLMEMGYPRGPKFSEILNSLKRAKMDGLVSSRADEEELLQKNFPLSNLHC
>NC_006138.1|WP_041277423.1|67021_67654_+|site-2-protease-family-protein
MTETINQIILLAPPLLLALTIHEFCHGYVAYKLGDPTAKLAGRLTLNPLSHLDPIGTIAFFFIKIGWAKPVPVNPNYFKNPRRDMLWVALAGPISNLLLAIISAIAAKTLWAIAPSLPATALIKAIVIPLNGMLVASVWINLVLCIFNFIPIPPLDGSKIVAGLLPRDLAIAYEKVEKYGFVILILLAFSGLLSKAIVPIIRFANGLLLS

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Crispr_ID: NC_006138_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006138_2

198142-199100

Unclear

Consensus_repeat	Method
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CRISPRCasFinder
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CRT
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	PILER-CR

13 spacers

cas8u1,cas3,csb2gr5,cas7

The CRISPR arrays of NC_006138_2

>merge|NC_006138|2|198142-199100|CRISPRCasFinder,CRT,PILER-CR
CCTTCAATGCAGTCACCCCTTTCGAGGTGATTGATACTCGCTCAGGGTTGCTCATATGCTCCTGCAGGGTCCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACATTTTTTCAGGTCGATATAGCGCATATCTTTGGCGCTTCAATGTAATCACCCCTTGCGAGGTGATTGACACGCAGACCTGCAGGCCGACCGTTATAACAGTCCTTGCTTCAATGCAGTCACCCCTTTCAAGGTGATTGATACCGTTTGCCACAGGAAAGAGCATCGGCGGTTGATCGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACTTCCCGAGATCGGTCAGGTCATAGACGCCAAACTGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACGTCGACAAGGTAGGAGCCGGGCCGAGAGTAGGGGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACTCGTCGTCCCAATCCATTCCGCTTGCAACAAACTGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACGTACAGACAGGCTTATCATCAGAGTAATAGGTGGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACATGGGCCGAATGGCAACTCTACGAGTTCTATCCTGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACTGTCTATCGCCTTGATAGCGGTAGATCCCTTGATGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACCCGATGATCGGGCAATACGTCACTTGTATCGGGTCGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACAACCTCGGTCGATGTTTGTGGGGCTGTGTTGATTTGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATACCAGCTCAAACTGATTTTGAGGACAGTGATAAACAGCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC

>NC_006138|2|2|198142-199100|CRISPRCasFinder
CCTTCAATGCAGTCACCCCTTTCGAGGTGATTGATAC	TCGCTCAGGGTTGCTCATATGCTCCTGCAGGGT
CCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	ATTTTTTCAGGTCGATATAGCGCATATCTTTGGC
GCTTCAATGTAATCACCCCTTGCGAGGTGATTGACAC	GCAGACCTGCAGGCCGACCGTTATAACAGTCCTT
GCTTCAATGCAGTCACCCCTTTCAAGGTGATTGATAC	CGTTTGCCACAGGAAAGAGCATCGGCGGTTGATC
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TTCCCGAGATCGGTCAGGTCATAGACGCCAAACT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	GTCGACAAGGTAGGAGCCGGGCCGAGAGTAGGG
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TCGTCGTCCCAATCCATTCCGCTTGCAACAAACT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	GTACAGACAGGCTTATCATCAGAGTAATAGGTG
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	ATGGGCCGAATGGCAACTCTACGAGTTCTATCCT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TGTCTATCGCCTTGATAGCGGTAGATCCCTTGAT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CCGATGATCGGGCAATACGTCACTTGTATCGGGTC
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	AACCTCGGTCGATGTTTGTGGGGCTGTGTTGATTT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CAGCTCAAACTGATTTTGAGGACAGTGATAAACA
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC

>NC_006138|2|1|198142-199100|CRT
CCTTCAATGCAGTCACCCCTTTCGAGGTGATTGATAC	TCGCTCAGGGTTGCTCATATGCTCCTGCAGGGT
CCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	ATTTTTTCAGGTCGATATAGCGCATATCTTTGGC
GCTTCAATGTAATCACCCCTTGCGAGGTGATTGACAC	GCAGACCTGCAGGCCGACCGTTATAACAGTCCTT
GCTTCAATGCAGTCACCCCTTTCAAGGTGATTGATAC	CGTTTGCCACAGGAAAGAGCATCGGCGGTTGATC
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TTCCCGAGATCGGTCAGGTCATAGACGCCAAACT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	GTCGACAAGGTAGGAGCCGGGCCGAGAGTAGGG
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TCGTCGTCCCAATCCATTCCGCTTGCAACAAACT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	GTACAGACAGGCTTATCATCAGAGTAATAGGTG
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	ATGGGCCGAATGGCAACTCTACGAGTTCTATCCT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TGTCTATCGCCTTGATAGCGGTAGATCCCTTGAT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CCGATGATCGGGCAATACGTCACTTGTATCGGGTC
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	AACCTCGGTCGATGTTTGTGGGGCTGTGTTGATTT
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CAGCTCAAACTGATTTTGAGGACAGTGATAAACA
GCTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC

>NC_006138|2|1|198143-199100|PILER-CR
CTTCAATGCAGTCACCCCTTTCGAGGTGATTGATAC	TCGCTCAGGGTTGCTCATATGCTCCTGCAGGGTC
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	ATTTTTTCAGGTCGATATAGCGCATATCTTTGGCG
CTTCAATGTAATCACCCCTTGCGAGGTGATTGACAC	GCAGACCTGCAGGCCGACCGTTATAACAGTCCTTG
CTTCAATGCAGTCACCCCTTTCAAGGTGATTGATAC	CGTTTGCCACAGGAAAGAGCATCGGCGGTTGATCG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TTCCCGAGATCGGTCAGGTCATAGACGCCAAACTG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	GTCGACAAGGTAGGAGCCGGGCCGAGAGTAGGGG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TCGTCGTCCCAATCCATTCCGCTTGCAACAAACTG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	GTACAGACAGGCTTATCATCAGAGTAATAGGTGG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	ATGGGCCGAATGGCAACTCTACGAGTTCTATCCTG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	TGTCTATCGCCTTGATAGCGGTAGATCCCTTGATG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CCGATGATCGGGCAATACGTCACTTGTATCGGGTCG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	AACCTCGGTCGATGTTTGTGGGGCTGTGTTGATTTG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC	CAGCTCAAACTGATTTTGAGGACAGTGATAAACAG
CTTCAATGTAGTCACCCCTTTCGAGGTGATTGATAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_006138.1\|WP_011187434.1\|203971_204490_-\|type-I-U-CRISPR-associated-protein-Cas7	cas7	cd09678_cas7_CAS-I-U	gnl\|CDD\|187869
NC_006138.1\|WP_011187436.1\|207027_207315_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NC_006138.1\|WP_041277457.1\|189764_190124_+\|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212144
NC_006138.1\|WP_011187439.1\|209985_210561_+\|rubrerythrin-family-protein	unknown	unknown	gnl\|CDD\|153100
NC_006138.1\|WP_049784969.1\|195349_197302_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273716
NC_006138.1\|WP_011187437.1\|207546_208629_-\|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|237363
NC_006138.1\|WP_041277461.1\|199249_199921_-\|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	unknown
NC_006138.1\|WP_011187417.1\|189034_189364_+\|PilZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|377796
NC_006138.1\|WP_041278156.1\|208860_209907_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_006138.1\|WP_011187419.1\|190440_191055_-\|DUF2971-domain-containing-protein	unknown	unknown	gnl\|CDD\|378585
NC_006138.1\|WP_156792170.1\|188011_188317_+\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_011187422.1\|193442_194132_+\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_011187431.1\|199922_202184_-\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|187827
NC_006138.1\|WP_011187440.1\|210649_211444_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133409
NC_006138.1\|WP_041277459.1\|192108_193428_+\|integrase-family-protein	unknown	unknown	gnl\|CDD\|271177
NC_006138.1\|WP_041278152.1\|187210_187570_+\|TusE/DsrC/DsvC-family-sulfur-relay-protein	unknown	unknown	gnl\|CDD\|377326
NC_006138.1\|WP_011187433.1\|203453_203879_-\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_041277462.1\|202167_203457_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	pfam09609_csb2gr5_CAS-I-U	gnl\|CDD\|312943
NC_006138.1\|WP_041277453.1\|187649_187904_+\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_011187423.1\|194435_195353_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_006138.1\|WP_011187434.1\|203971_204490_-\|type-I-U-CRISPR-associated-protein-Cas7	gnl\|CDD\|187869	cd09738, Csb1_I-U, CRISPR/Cas system-associated protein Csb1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; Contains several motifs similar to Cas7 family; also known as GSU0053 family.	1.24408e-76
NC_006138.1\|WP_011187437.1\|207546_208629_-\|branched-chain-amino-acid-aminotransferase	gnl\|CDD\|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	0
NC_006138.1\|WP_041277457.1\|189764_190124_+\|nucleotide-pyrophosphohydrolase	gnl\|CDD\|212144	cd11537, NTP-PPase_RS21-C6_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs. RS21-C6 proteins, highly expressed in all vertebrate genomes and green plants, act as house-cleaning enzymes, removing 5-methyl dCTP (m5dCTP) in order to prevent gene silencing. They show significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, RS21-C6 contains a single MazG-like domain and functions as a tetramer (a dimer of dimers) with a typical four-helical bundle. Divalent ions, such as Mg2+, are required for its pyrophosphatase activity. This family also includes a pyrophosphatase from Archaeoglobus fulgidus (Af1178). Although its biological role remains unclear, Af1178 shows significant sequence similarity to the mouse RS21-C6 protein.	1.39265e-38
NC_006138.1\|WP_011187439.1\|209985_210561_+\|rubrerythrin-family-protein	gnl\|CDD\|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	1.7201e-57
NC_006138.1\|WP_049784969.1\|195349_197302_+\|hypothetical-protein	gnl\|CDD\|273716	TIGR01613, putative_primase, phage/plasmid primase, P4 family, C-terminal domain. This model represents a clade within a larger family of proteins from viruses of bacteria and animals. Members of this family are found in phage and plasmids of bacteria and archaea only. The model describes a domain of about 300 residues, found generally toward the protein C-terminus. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	2.33312e-62
NC_006138.1\|WP_011187419.1\|190440_191055_-\|DUF2971-domain-containing-protein	gnl\|CDD\|378585	pfam11185, DUF2971, Protein of unknown function (DUF2971). This bacterial family of proteins has no known function.	2.57768e-07
NC_006138.1\|WP_041278156.1\|208860_209907_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.60856e-29
NC_006138.1\|WP_011187436.1\|207027_207315_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	2.14115e-51
NC_006138.1\|WP_011187417.1\|189034_189364_+\|PilZ-domain-containing-protein	gnl\|CDD\|377796	pfam07238, PilZ, PilZ domain. PilZ is a c-di-GMP binding domain which is found C terminal to pfam07317. Proteins which contain PilZ are known to interact with the flagellar switch-complex proteins FliG and FliM. This interaction results in a reduction of torque generation and induces CCW motor bias. This domain forms a beta barrel structure.	6.45706e-05
NC_006138.1\|WP_011187431.1\|199922_202184_-\|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187827	cd09696, Cas3_I, CRISPR/Cas system-associated protein Cas3; Distinct Cas3 family with HD domain fused to C-termus of Helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DNA helicase Cas3; This protein includes both DEAH and HD motifs; signature gene for Type I.	0
NC_006138.1\|WP_011187440.1\|210649_211444_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133409	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BltR (BmrR-like transporter) of Bacillus subtilis, and related proteins; N-terminal domain. Blt, like Bmr, is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. These regulators are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains are often unrelated and bind specific coactivator molecules. They share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	8.98985e-41
NC_006138.1\|WP_041277459.1\|192108_193428_+\|integrase-family-protein	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	6.79864e-19
NC_006138.1\|WP_041278152.1\|187210_187570_+\|TusE/DsrC/DsvC-family-sulfur-relay-protein	gnl\|CDD\|377326	pfam04358, DsrC, DsrC like protein. Family member DsvC has been observed to co-purify with Desulfovibrio vulgaris dissimilatory sulfite reductase, and many members of this family are annotated as the third (gamma) subunit of dissimilatory sulphite reductase. However, this protein appears to be only loosely associated to the sulfite reductase, which suggests that DsrC may not be an integral part of the dissimilatory sulphite reductase. Members of this family are found in organisms such as E. coli and H. influenzae which do not contain dissimilatory sulphite reductases but can synthesize assimilatory sirohaem sulphite and nitrite reductases. It is speculated that DsrC may be involved in the assembly, folding or stabilisation of sirohaem proteins. The strictly conserved cysteine in the C-terminus suggests that DsrC may have a catalytic function in the metabolism of sulphur compounds.	2.48659e-17
NC_006138.1\|WP_041277462.1\|202167_203457_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl\|CDD\|312943	pfam09609, Cas_GSU0054, CRISPR-associated protein, GSU0054 family (Cas_GSU0054). This entry represents a rare CRISPR-associated protein. So far, members are found in Geobacter sulfurreducens and in two unpublished genomes: Gemmata obscuriglobus and Actinomyces naeslundii. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	0

>NC_006138.1|WP_049784969.1|195349_197302_+|hypothetical-protein
MIEFTPLTEAQNMLYEATVSVAKEEVHAEADRIRQQYMSVEAIKLAEKTGVDVEHAEETVRLRCNGHLSPEDIIYFQNGSTATVEEMLADRSKYDGTPCADPLEREEGLNRAMFYANADTGKPLIHSFLHGGQIHHLTGRQEEPVEEHAPSFSELLERAATLKAGDTKGMKDILELATALDSIEEQELLRKIKKNTGMPLQAMRSYTRKGQVDSKDLDHLDIARKLLEEIGKENVLNCEDGVFIWREKGVWEPMRKGELKHRLQKLIEGKMRVMSQWVVGATEVFTNDVYRANHEFNIGDPNVINCLNGELHLNHKTGSWEPKSHDKLAYRTSQIPVEFDPTATAPRFKQFLNEIFETDEDSQDKTRALLEMCGYTMVAHCSYELFVILIGTGANGKSVFLSLLEAIVGPKNTVGVQPSQFDNRFQRGHMRHKLANIVTEIKQGEVIADAELKGIVSGEPSTVENKFKDPFTMRPHVTCWFATNHMPHTRDFSEALFRRALILKFNRVFSDEEKNPKLKDELFAELPGILNLALHAYANAVLNGFTKPDSSEQAKEEWRLEADQVQQFVEDCCEKSPYEEIESSTLFRAYRSWAETNGIRKMLSQKSFRDRLTRLGFGSKRNKQARLVTGIAMANNFPGSAADLLGELLS
>NC_006138.1|WP_011187423.1|194435_195353_+|hypothetical-protein
MNTKRKAVPPQKVGAMGETASNQQAKYSSFPDNQQGPTDNPAASQRQRIFPHPKADEPTTDIAFTIITNHDGPLTKTIRPDGQGGIIKKPAANLVRGVTKRVTMPFRKFGPFLRTLQNNQALCHGVSDYPQANITSRAKFNGEPDTITRTSEYFHYPTGAGIGMFDHDPKPGQKTLSADELLDIIYSVCPDFRRLSTWWTPSTSSCIFDNNKNELTGIGAGFHLYFPFEPADKLPEFADWLSRQLWLAGHGHIFISRTGSLLTRTVFDLTVFSPERLDFVAGADCIDCNQRLPEPVYRKGLEVWA
>NC_006138.1|WP_011187422.1|193442_194132_+|hypothetical-protein
MKWMPVVSEIPWPDDNGEVIGTRKYISCYFAHFSDDEEKRIFNILEKYPVSEVNLFTSMLAKICTDYGVFLKQKRDHQIRKEIDDKLPILEKAHSQLKLLQKQGLPIEHIKSVPGVCHSEEEKSRHYADKHINKKAYCDLPVCARRAEEALESLLGVLRDLQPDKPGRGRVETEGGFAQAIADAFAEVFNKKPSTWREGVLSQILAICLEGLGIPHENPERRLKNLVHK
>NC_006138.1|WP_041277459.1|192108_193428_+|integrase-family-protein
MPRLTLNRIRNAKLPPNKKQIFLWDEDAKGLGVRITGSAKVFIFQSRMLMPDKNGILKPSTFRIKIGGCDSVLLEDARNVARRYAAQVAEGIDPRQARQRTAENEATERQERKRQDVTIGKAWPTYMEERRPNWSTKYYSDHERIISPGGKQKKRGKGLTVAGPLASIANLPLSSVTADSIKKWLADEQPKRPTETRRAFEMLRTFLNWCEADKRYHGLAPPNACSAKIKKDNLTKKNSRDDALQREQLSVWFASVRRYENKVLSAYVQMLFLIGARREELLSLKWSDVDFRWKKVHILGKGAVPRDLPLTPYVAALLSKLPRRNEWVFSSTRGKEGRLQSPTKAFQKMMSRAEIDDITLHGLRRSFSTLSEWLETPVGIVYQIQGHEPSATAEKHYKKRPVDLLRKWHIKIEAWILEEAGVEVPGADQETGFRLVKIV
>NC_006138.1|WP_011187419.1|190440_191055_-|DUF2971-domain-containing-protein
MKLYKFRSLDNLEFVLDILLNQRLYCSSYDSLNDPLEGLFYTIISPRGNQKRVRQYKSIDDLPTFNSDLKICSLSKSLEDIRMWSHYANGHTGVAIEIEFSDYEADVTEVNYDSGLKKHGTTILAGATPNEVLSYKTEHWRYENEYRIIGQDEYYPIKGRVTAVYFGVRASDFHKDILKKSVSNNISLLETRLDRKNIVVRAVK
>NC_006138.1|WP_041277457.1|189764_190124_+|nucleotide-pyrophosphohydrolase
MDHNFIQEKLRVFAQERNWDQFHSPKNLAMALAGEAGELLEIFQWLTEDESKKENIKAKDKQLAAEELADIQLYLLRIADKLDINLEEATFAKLEKNAEKYPISLAKDNAIKYNRRDER
>NC_006138.1|WP_011187417.1|189034_189364_+|PilZ-domain-containing-protein
MNKRRYPRMNGKNLRFDISDGSGFFSGYVSDISRFGILLDDIPLKLDHSAKTLSLVVSGNGKNFKMMAIPKWTVEKGISKTIGMELINVPYIWAGFIREFAPKTSLTHP
>NC_006138.1|WP_156792170.1|188011_188317_+|hypothetical-protein
MGGKNLRVDISDGRGFYSGYISDVSRFGMQLNSIAIKLNQDVKTLSVVVTVNGKNFKMMAIPKWEVKEGGSKTMGMELINVPYSWAGFIREFDQKKAQGHP
>NC_006138.1|WP_041277453.1|187649_187904_+|hypothetical-protein
MFNANELCNKITSLHPELGACGIDITVTKDDKENRWLVHLNKGEHSLNHFLEMPDADHCMEGQQCLSLGLEIAQLQKNIKGEQF
>NC_006138.1|WP_041278152.1|187210_187570_+|TusE/DsrC/DsvC-family-sulfur-relay-protein
MTTLRSGDTTIILDEYGFLDKDQVWNKEVAMIIAEHEGFTELNEEKMNIINFMRKYYTENHNFPILAEVCKKTGDTCRDCVAREFTDPMRAWKIAGLPKPPSIFFTTFDGKKYSPNPFY
>NC_006138.1|WP_041277461.1|199249_199921_-|hypothetical-protein
MQYKMQGLFETNAQAWMAAVGCFSIVSRMGHKAHLLWEHQHPVLLGVDENIVLESLSRYLAEGSSLLEELPKSKTAEKIPLDLTAGRVSFSNVITTMLISVTRDDILNALNLPWMNEDNITSLGWDVGANKMAAKVGGMKAPTSSPHRGVIAGQWLAAEALPVTSLGVRKGFYQWVTWSVPLDISGVWAVVQSKSTEWGGDLYEATIQRNGQMGYLLPARRSH
>NC_006138.1|WP_011187431.1|199922_202184_-|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MSLKFDEWYQGKHGYSPFPWQLSLAERVLAGQPPESISTPTASGKTAIIAAWHYAVEIGAKVPTRLIYIVDRRLIVDSVTEYAEKIGCTVIKMRGGVTIDDSWMLNPHEPVVIVSTVDQAGSRLLWRGYGVSPKSAPIHAALIGNDAMIVLDEAHISTPFAETLKQIMNLRPPSILPWHVVTMTATPVTDDRTMTLSAKDYAHPVLKKRLASKKIVKLVKPSDEQFLSTMVKEANLLMADVKGVVAVVCNTTKHARAIFAKLPGEKILLTGRVRPADKDEILNQYLPQMLSGSRGRGRQPLFVVATQTIEVGADLDFDALVTQNAPIDALQQRFGRLDRLGELQACQGAIVYLDLGKDQDCKVYGKKILKSTWSWLKKIQHGKGKNKRVDFGVLAIKKAIEASSPPMREISLPFPLSHTDLRCLRQTMPSVDMDISPWLHGDDKDNITVQVVWREDLPCETEQWVEIVQAAPPVMAEAMPCPIYEVVRWLGRRSVVVGDRVVRGDSIRGGCMIVIPTRYGGYDEWGWMPQKCDPVKDLGNQVGAKFRLVGAGEDSDIPELLKEANAPFVKPLITFYPAGVIVTETPRRKRSGDEVALSDHLDNVFEVAKNFSADEAVRQAARLHDIGKQDPRFQTMLGACSTPLAKSNHISPWAAKVARSMSGLPKGWRHEVASVSMLSDEVSDLLKYLVGTHHGYNRSVLSISGDFALWHKAGGSDWGSMTCRLNEEYGAWQLAYLEAMVRLADWVQSKSEE
>NC_006138.1|WP_041277462.1|202167_203457_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MSDFAAQIEFLVKPQLSDPASPQRGEWPPAPDRKFQAMVATAAEIGEDLEVLKYLESPPLMQFEEALCPRAPLQYVPENFRRGKDYHTGTARHLPVVHPKNNIVSYLWRDVPEKCIAPLTKIVEQLTHIGRATSLVIGRVVPADSVKFNWVPDKDGGLRVRTPYTGRLQELIAHFEVGARSPAAPYTSYREKKTLVSNERWGELFVLRPQRQLDIHQTTYWTDKLRRAVISQAEDSSLPPLVHGHGDYRHVAWAAIPDVGHKYAKGHILGLGCWLPSDVSDLEVGVVGASLMRVRNLGEVELELDNVGLKGLQSSAWNKASKSFATVTPVALDRWPTKKVSPESIVAESLAKMGLPLPAYISCGNTSPIKGTIDARKYPSRKNRRYMCHVVIVWSSYIIGPIIIGADRYFGSGLCRPFYSEELNNVSQI
>NC_006138.1|WP_011187433.1|203453_203879_-|hypothetical-protein
MGHSDIPDTADKGVFAGRIELNGAISLTRLSRYSFPDEAGTSSPERDQAGREVLIQLALLGVSLVMDKLDLRSGCELYTASRESYVLRSNGEQVAFNLPSSTAKLKEALAVAKEHGLSFNQEPICLTAGSALVGLLPRGEE
>NC_006138.1|WP_011187434.1|203971_204490_-|type-I-U-CRISPR-associated-protein-Cas7
MSDVAISIKANLKNVNGSDHIYPPTFAGVGHNFVALDKGTGKAKAVQVDSVGSFANRIEAELAALGILPEITTSVANQTLSVNELPHRIYDAILRDSFLGEDSWRNSDIGHQLLSSTTKNATALLLMLHDTSLGGWDSHAGKSVKGVKISRSVSCEIWGYDVFVAQHTSPKN
>NC_006138.1|WP_011187436.1|207027_207315_-|co-chaperone-GroES
MKIRPLNDRLLVKRLAEEEKTAGGIIIPDSAKEKPAEGQVVAVGPGKVSDSGERVALQVKEGDLVLFSKYGGTDVKLDGEDFLIMREDDILGIME
>NC_006138.1|WP_011187437.1|207546_208629_-|branched-chain-amino-acid-aminotransferase
MWENLDVALEKVSVENLKEKPSSENLCFGSDFTDHMFAMTWSRENGWHDAKICPYHNLVLDPAAMVFHYGQAIFEGMKGYKGKDGQTYMFRPTDNLERMNQSAVRLCMPRLPVDKVLKSLKALLYLEKDWIPEAPGSSLYIRPTMIAVEPSLGVRPSEKYYFFVIMSPVGAYYKEGCNPTKIYVSDEQARAVPGGVGNIKTAGNYAASLYTAEIARKKGCSQVLWLDAKEFKYVEEVGTSNIFFRIGDELITPPLGGSILGGITRDSILKLARSWGLNVSERKITIEEVLRASEDGTLLESFGTGTAAVISPVGEIVYKDKSYIINAGKAGELSQRLYAELQGIQYGELEDPFKWVERVG
>NC_006138.1|WP_041278156.1|208860_209907_+|AI-2E-family-transporter
MRIKYFLLVFAIAFFFLGRILWPFWSILVLSFLLVNIFQPVYLFLSKQLPRSVASGLTCLMIIALVFFPLLFFTGALTGEALSFYNWVRDSQVWMRFQDFIQQSQFITRMQAPLKDFGIDFQPAQITASLAYFAKAGGLFLYDQASSWAANILQSVALFFIMILVIFFLFMDLLRLKEFLFKLSPLPEDENRLLVKKFEEIANAILKGSGICGIIQGIIGGVLFSIMHLPSPILWGCIMSVLAFLPIFGIGLVMLPAALALAIDGQTATASSLVISYLVLSLGMEYLIKPKLVGSQVEMHTLLVFLSIIGGISVYGILGIIYGPLIITAFLTLSNIYLRRYDQYVQIM
>NC_006138.1|WP_011187439.1|209985_210561_+|rubrerythrin-family-protein
MPKIQGTRTEQNLLKSFAGESQARNRYTYFASIARKEGYVQIGDIFEETSNQEKEHAKRFFKFLEGGNVEITASFPAGRLGNTSDNLLAAAEGEFEEHSSLYPGFAKIASEEGFEEIAAAWLAISVAEKQHEKRYRDLLANIKSSQVFERATEQSWRCRNCGYIHHGTQAPELCAACLHPKAHFEILGENW
>NC_006138.1|WP_011187440.1|210649_211444_-|MerR-family-transcriptional-regulator
MEIRFMAGEMARLHGISKQTLLYYDKINLLQPREKCRLSGYRYYTLDQFEELELVLYLKNLGISLKEIKDYLDTSSIEERMEKLEGQEQLIQEKMEQLRQTDRHLKAIIESMRANNALIPFEMGVKVLPKRHIVAEPVLPPFDLYSLEVAIKKLINASLPDQKLEINDLLIFVEPKDEVELFKGVAVEVPRPGRAAESMPGGNYAYLYHKGPYGELPASWLQLYAYLDKFGLRAIGPCLEKMLLGAFAVADEQEFLVELQVMVE

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Crispr_ID: NC_006138_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006138_3

748337-748447

Orphan

Consensus_repeat	Method
AAAACTTGAGGAGACGGCCAATATACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006138_3

>merge|NC_006138|3|748337-748447|CRISPRCasFinder
AAAACTTGAGTTGGCGGACAATATACAGATGTATAAAGCTAGAAAACTTGAGGAGACGGCCAATATACATCTGTACATTGATCAAAAACCTGAGGAGATGGCCAATATACA

>NC_006138|3|3|748337-748447|CRISPRCasFinder
AAAACTTGAGTTGGCGGACAATATACA	GATGTATAAAGCTAGAAAACTTGAGGAGACGGCCAATATACATCTGTACATTGATCA
AAAACCTGAGGAGATGGCCAATATACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_006138.1\|WP_011187933.1\|757844_760484_-\|MCE-family-protein	unknown	unknown	gnl\|CDD\|225553
NC_006138.1\|WP_011187929.1\|753129_753594_-\|NADH-quinone-oxidoreductase-subunit-NuoE	unknown	unknown	gnl\|CDD\|376507
NC_006138.1\|WP_011187922.1\|742878_743943_+\|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380618
NC_006138.1\|WP_011187926.1\|746511_747999_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226364
NC_006138.1\|WP_011187930.1\|754022_754295_+\|OadG-family-protein	unknown	unknown	gnl\|CDD\|377277
NC_006138.1\|WP_041277582.1\|741814_742504_+\|DUF2293-domain-containing-protein	unknown	unknown	gnl\|CDD\|370799
NC_006138.1\|WP_011187927.1\|748589_751253_-\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|225918
NC_006138.1\|WP_011187925.1\|746025_746508_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236395
NC_006138.1\|WP_041278289.1\|736142_736508_+\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_011187917.1\|737621_738248_+\|uracil-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234653
NC_006138.1\|WP_041277583.1\|744019_745078_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226962
NC_006138.1\|WP_011187924.1\|745077_745998_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224005
NC_006138.1\|WP_162096624.1\|760480_761860_-\|PqiA/YebS-family-transporter-subunit	unknown	unknown	gnl\|CDD\|225542
NC_006138.1\|WP_173362837.1\|754378_756145_+\|biotin-attachment-protein	unknown	unknown	gnl\|CDD\|227349
NC_006138.1\|WP_083818927.1\|751256_753140_-\|4Fe-4S-binding-protein	unknown	unknown	gnl\|CDD\|224806
NC_006138.1\|WP_041277581.1\|739841_741728_+\|transketolase	unknown	unknown	gnl\|CDD\|226467
NC_006138.1\|WP_156792197.1\|763726_763903_+\|hypothetical-protein	unknown	unknown	unknown
NC_006138.1\|WP_011187916.1\|736529_737426_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_006138.1\|WP_083819011.1\|756228_757728_+\|sodium-ion-translocating-decarboxylase-subunit-beta	unknown	unknown	gnl\|CDD\|377182
NC_006138.1\|WP_156792344.1\|762136_763057_+\|PEGA-domain-containing-protein	unknown	unknown	gnl\|CDD\|285503

Protein	Function_ID	Function_description	E-value
NC_006138.1\|WP_011187933.1\|757844_760484_-\|MCE-family-protein	gnl\|CDD\|225553	COG3008, PqiB, Paraquat-inducible protein B [General function prediction only].	4.87848e-94
NC_006138.1\|WP_011187929.1\|753129_753594_-\|NADH-quinone-oxidoreductase-subunit-NuoE	gnl\|CDD\|376507	pfam01257, 2Fe-2S_thioredx, Thioredoxin-like [2Fe-2S] ferredoxin.	5.81369e-67
NC_006138.1\|WP_011187922.1\|742878_743943_+\|BMP-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380618	cd19963, PBP1_BMP-like, periplasmic binding component of a basic membrane lipoprotein (BMP) from Brucella abortus and its close homologs in other bacteria. Periplasmic binding component of a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria. These outer membrane proteins include Med, a cell-surface localized protein regulating the competence transcription factor gene comK in Bacillus subtilis, and PnrA, a periplasmic purine nucleoside binding protein of an ATP-binding cassette (ABC) transport system in Treponema pallidum. All contain the type 1 periplasmic sugar-binding protein-like fold.	3.13081e-173
NC_006138.1\|WP_011187926.1\|746511_747999_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226364	COG3845, COG3845, ABC-type uncharacterized transport systems, ATPase components [General function prediction only].	0
NC_006138.1\|WP_011187930.1\|754022_754295_+\|OadG-family-protein	gnl\|CDD\|377277	pfam04277, OAD_gamma, Oxaloacetate decarboxylase, gamma chain.	7.41991e-12
NC_006138.1\|WP_041277582.1\|741814_742504_+\|DUF2293-domain-containing-protein	gnl\|CDD\|370799	pfam10056, DUF2293, Uncharacterized conserved protein (DUF2293). This domain, found in various hypothetical bacterial proteins, has no known function.	9.70418e-25
NC_006138.1\|WP_011187927.1\|748589_751253_-\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0
NC_006138.1\|WP_011187925.1\|746025_746508_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|236395	PRK09177, PRK09177, xanthine-guanine phosphoribosyltransferase; Validated.	2.69063e-103
NC_006138.1\|WP_011187917.1\|737621_738248_+\|uracil-phosphoribosyltransferase	gnl\|CDD\|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	1.02086e-123
NC_006138.1\|WP_041277583.1\|744019_745078_+\|ABC-transporter-permease	gnl\|CDD\|226962	COG4603, COG4603, ABC-type uncharacterized transport system, permease component [General function prediction only].	2.37389e-92
NC_006138.1\|WP_011187924.1\|745077_745998_+\|ABC-transporter-permease	gnl\|CDD\|224005	COG1079, COG1079, Uncharacterized ABC-type transport system, permease component [General function prediction only].	2.26305e-96
NC_006138.1\|WP_162096624.1\|760480_761860_-\|PqiA/YebS-family-transporter-subunit	gnl\|CDD\|225542	COG2995, PqiA, Uncharacterized paraquat-inducible protein A [Function unknown].	2.72971e-95
NC_006138.1\|WP_173362837.1\|754378_756145_+\|biotin-attachment-protein	gnl\|CDD\|227349	COG5016, COG5016, Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion].	2.74076e-151
NC_006138.1\|WP_083818927.1\|751256_753140_-\|4Fe-4S-binding-protein	gnl\|CDD\|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	0
NC_006138.1\|WP_041277581.1\|739841_741728_+\|transketolase	gnl\|CDD\|226467	COG3958, COG3958, Transketolase, C-terminal subunit [Carbohydrate transport and metabolism].	3.77374e-33
NC_006138.1\|WP_011187916.1\|736529_737426_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.65096e-10
NC_006138.1\|WP_083819011.1\|756228_757728_+\|sodium-ion-translocating-decarboxylase-subunit-beta	gnl\|CDD\|377182	pfam03977, OAD_beta, Na+-transporting oxaloacetate decarboxylase beta subunit. Members of this family are integral membrane proteins. The decarboxylation reactions they catalyze are coupled to the vectorial transport of Na+ across the cytoplasmic membrane, thereby creating a sodium ion motive force that is used for ATP synthesis.	0
NC_006138.1\|WP_156792344.1\|762136_763057_+\|PEGA-domain-containing-protein	gnl\|CDD\|285503	pfam08308, PEGA, PEGA domain. This domain is found in both archaea and bacteria and has similarity to S-layer (surface layer) proteins. It is named after the characteristic PEGA sequence motif found in this domain. The secondary structure of this domain is predicted to be beta-strands [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].	0.00030772

>NC_006138.1|WP_011187926.1|746511_747999_+|ABC-transporter-ATP-binding-protein
MTSSAIRLENISKSFGDVHANRDVSLDIRKGRVLALLGENGAGKSTLMSILAGQLQPDSGTLYVEGEAVVFSTTEKAIGAGVGMVYQHFKLVEAMTVAENIILGRKGSFLLNKAAMYRDVQDLANQYGMDVDPRAKVHTLAMGEKQQVEILKLLFRQSNILIFDEPTAVLTPTEAEGLFVAIKRMTELGKGIVFISHKLEEVMRIADDVAILRRGEVVDTLLVEDVSSTADLAERMVGKAVLLEVNRQPLEPRQTVLRVDNLQDEVLKGVSIDLRKGEILGIVGVAGNGQKQLIETICGLKKPRLADSVSLFGLHWKEFFSNRSWDHALSYIPEDRQGLATCRDLDLVDNFLLTTREGFTNGPFLDRAAAAEKLEHLVELFDIRPPNIHALAWHLSGGNLQKMVLAREFYRKPRLIVAEQPTQGLDISAAEEVWNLLLKTREQAGVLLVTGDLSEALALSDRIAVMCGGEVIGTFSVDDTEQVDRIPQMMAGIKQ
>NC_006138.1|WP_011187925.1|746025_746508_+|xanthine-phosphoribosyltransferase
MSDQYKRTYPISWDQLHRDSKALAWRLLDKDFFKGIIAITRGGMVPAAIIARELDIHLIDTICISSYDWKEKKGEADILKGFDGDGEGWLLIDDLVDTGRTAEVVKNLIPKAHFATVYAKPSGRPLVDTFVTEVSQDTWILFPWDTESQFAAPLIGREQR
>NC_006138.1|WP_011187924.1|745077_745998_+|ABC-transporter-permease
MGIEIIIPLLAATVQAGTPVLLATLGEIFTEKSGVLNLGVEGVMLVGALAGFVVSRYTGDPTLGFLAAGCAGLLLTSLHGIVCLWFQGNQVVSGLALTILGTGLANYLGTSFVGLSAPGFSPVNVPFLSAIPAIGPIFFQHDPLVYVSYLIPFVLCFLFNSTRFGLSLRSVGEYPAAATAAGINVNAYRWVGIWGGGFLMGLGGAYLSLAYTHMWTTNLTGGRGWIAVALVIFAFWRPGRAVFGAYLFGGIMSLQLRLQASGIAVPSSLLLMLPYFLTIFVLVLSSWRKSSSDEPAALGVNVEPID
>NC_006138.1|WP_041277583.1|744019_745078_+|ABC-transporter-permease
MLQLRVAKRQESLGWGSFFVLLAALALSLVLSGFLLYLRGTPPLDGLIAMFTGGFGSKWALEDSLLKAIPIFLCSLGVAVAFRLQVWNIGAEGQFALGAIGSTWVALTFPNLPGFLMLAAMILMAVLAGGVWGVIPAILRQKFKANEIIVTLMMNYIAILILQYLVYGAWKDPSSFGFPMTREFSEAAIVGKIGESSVNWGLAHCFVLGVVVWAFFKFTKTGFELKAAGSSVPAVKYAGIRYDFLVILVMGISGALAGWAGFLEASATTNRLQPAIMVGYGYTAIVVAWLARLHPLSIAIASFLLAGLRVGVENLQLDFQVPAAFGGIIEGLILLTVLAGGFFTYYKIVRRK
>NC_006138.1|WP_011187922.1|742878_743943_+|BMP-family-ABC-transporter-substrate-binding-protein
MRLFKVLLAIALTMLVVGTSQAAKKETKVGFVYVSPIGDAGYSYAHDLGRQAVAKMPGVSTSYVESVPEGPDSERVISNMARKGYDVIFSTSFGYMDPTLKVAKRFPKTAFLHCSGFKKSANMGNYFGRMYQARYLSGMVAGYMTKSNTIGYVAAFPIPEVIRGINAFALGLQSVNPQAVVRVVWTKTWYDPATEKEAAKSLLDVGADVIAQHQDSPGPQEAAQEKGVYSIGYNSDMSVFAPKSHLTAPVWNWAPYYTSVVKEVQAGTWKADSAWLGLETGVIALAPYGDMVPQDVRDAVEVRKQEIASGKYKVFAGPIEDQSGKVRIASGKTASDESLLGMMWFVNGVVGTTE
>NC_006138.1|WP_041277582.1|741814_742504_+|DUF2293-domain-containing-protein
MADEKNLVLRLGGNGRTLLTSDGKIVHPPAGWKLLPPGDAGLTRRVKAMGSHWLVQEKRGRRTYSKGIWAKGSHIVHAREEIEAKRATPAYIKKMATDVKRREKKQEEYVDDFHQAILLYLQFHRRHSMIAEKIAGQVARHATPVGSGTVARTQRIPLEKRAEAAVIAWMRHKTTAYDQMSIAQVKGRRREVRRELAHQSVNLLARYRQGDDIPLTCPLYRAVAITSPL
>NC_006138.1|WP_041277581.1|739841_741728_+|transketolase
MDFPIDLKEYTPLKFDLGQTEMTDEQRQTLKKNIDVVRDGLVFFTALANVKSLGGHTGGAFDIVPELLIVDGFMKGSDSIVPVYYDEAGHRVAIQYMMSVLNGYNDAEALFHYREFGKGFYGHPERDERDGIFFSSGRLGHMWSHVNGVAEFDRDKTLVMFGSDGSQMEGDDAEAARYAVARNLNVKLFIDDNNVTIAGHPSEYMKGYDLNKTLSGHGLTVSEGDGEELDGLFARIQQAFTQSGPVAVINKRPMAVGVKGIHGLPKGHDVIPVDMAVEYLTARGQNEAVSYLQNFKTEKTKRSYLGSSPETAKSRDEFGKIVCGLLDEMKEPEKRVLVVDSDLEGSCGLHHIRKNHPEVYVSAGIMERNNYSVAAGFGSEAGRQGIFGTFSAFLEMLISEITMARLNRANVLAHFSHAGVDEMADNTCHFGINNFFADNALAEDDNTRLYFPADALQMKAILQRIFHDMGLRFVFSTRSATPFLLSESGEKIYGEGYSFEPGEDEIIREGKDGYIVTYGEMTYRCLDAIEQLKAEGIEVGLINKPTLNVVDEEMIAKVGASPLVLVVESQNTKTGLGSRYGSWLLERGFAPKYSLLGTSRPGQGGISEQLDFQGIDVDGIKAKIKAML
>NC_006138.1|WP_011187917.1|737621_738248_+|uracil-phosphoribosyltransferase
MSLHIADHPLVKHKLGLMRQNDISTKDFRALASEIARLLTYEAVKDLPTEKHIVDGWAGPVEVDRLKGKKITIVPILRAGLGMMDGVIDLIPSAKVTVVGFYRDEETLEPVEYYVKTASEMSERVALIIDPMLATGGTLIATIDTLKKAGSKKIKGLFLVAAPEGIKKVQDAHPDVEIYVAAVDERLNEAGYILPGLGDAGDKIFGTR
>NC_006138.1|WP_011187916.1|736529_737426_+|DMT-family-transporter
MSRLQANLLLSLAALIWGSSFVVQQIGTGNLDAASFTGARFLLGSLVVLPFALRQFLHVQREVRAFTLRDGLGIALTGSVLCVAAALQQYGILRTTVTNSGFLTALYVPMVPILALLVFRKKPHWSAWPASICCFVGTYIMSGAQNVVLASGDLWVISSTIFWASHVLLIGIMVQKTEAPLVVACGQFFICGILGLFLGQYLESPDLNVFAGALTGILCMGFFSVALAFTFQVIGQRYTPAPDAAIILSSETVFAALCGAIFLGERVSDFQLAGGLLIFGGIIAVEILPMLKTARILS
>NC_006138.1|WP_041278289.1|736142_736508_+|hypothetical-protein
MINRGAVLLRYKQPMVDWVNSTHPADEEQEVLTMAALNADRTIFLVDDRDVEELDQWLALNFVQLFETELEDWSEDQKLWPAPLDMETFLNWFEVECHGLIIDTVGAPIVAMDEFMDDVAE
>NC_006138.1|WP_011187927.1|748589_751253_-|formate-dehydrogenase-subunit-alpha
MKKVTLTINGRSVTAPEGSYVLQAALQKGIYIPHLCYHNDLEPVGACRLCTVRVNGRWDALSCKTPVEEGMVIETETETIAKTRKIAIELLIADHDMDCLACARNTTCKLQQAADYIGVNKKHLARLKKPEVLLPIDDSNPFFDFDPNRCVLCGICIRTCDELQNINAIDFAYRGLTTKVAGFGDKARILSNCESCGECVARCPVGALTEKDYVKPSHWVKTVCAYCGCGCGLDLGVRDNKIVSARGEHGNPANRGRLCVKGRFGFNYVNSKERLTTPMVRRPEGFVPVSWDEALDLIADNFAKNKGDSFAAVSSAKCTNEENYLLQKFTRTVMKTNNIDHCARLUHAPTVAGLATAFGSGAMTNSIAEIGDAQVILAIGTNTTAAHPIIALQIKDAVRRGAKLIVINPKRIDLCKHAHIFLQNTPGSDIPLLMTMMRIIVEEDLIDKEFIEERCENYPAFLASLQQFELEDVAELTGIPAETIREAALCYATESPATILYCMGITQHVHGTDNVLATSNLALLTGNVGKESTGVNPLRGQNNVQGSCDMGALPDVYPGYQKVVNNTAAFEEKWQTSLSAVPGKTHTEIFDGLYDGSIKSVYLIGENPVLSEANASHAIEAMNRAKFLVVQDIFFSETAELADVILPASSFAEKDGTFTNTERRVQRVRQAIEPVGDSRPDWWIIKEIATRMGAKGFDHEGPEQIMEEISATIPNYAGINYDRLQHGTLQWPCPSTDHPGTKFLHAERFATANGRARFMPLKTRKTTEQVDKKYPLLLNTDRSLFHFHGTMTRRVFGLNVLDRGENLIIHPEDAEKFSLTDGEIVEVRSRRGAVKVAVEINDSCRPGSVSMSFHFSETPTNMLTSGALDPVAKTPGTKICAVQINKL
>NC_006138.1|WP_083818927.1|751256_753140_-|4Fe-4S-binding-protein
MTIKEIRQQAEANWQSLIKGTVIYIGAATCGRSAGALKTKKAFETELAKQNVKAEIVEVGCFGPCYTEPLICIARPGKTKLFFQNVDGERAEELVTGYLQTGEIPRDYLFAAVPEDGIEREKELPYLDEKPEFARQKRILFASFGFTDPTNIEHYLVHDGYLALEKSLQEGPDMVLTEIKKSALRGRGGGGFPAARKWEAGRKATGHPKYVVCNADEGDPGAFMDRSVLEGDPHAVLEGMAIAGLTIGSEKGYIYVRAEYPLAIARLQNAIDQAKEKNLLGANILGTDFSFDIELFQGAGAFVCGESTALTQSIQGYRGMPKASPRPRTTDEGLFDKPTLLNNVKTFAYVPKIINSGGESFAAIGTEKSKGTAVFALTGMVKHCGLIEVPMGTTLREIVFELGGGMVGESPFKAIQSGGPSGGCLPAHTLDTPVDYDSLVSAGAMMGSGGLVVMDESTCMVDIARYFLDFTQKESCGQCTLCKLGTKQMLNILEDIVAGRGKEGDIELLLEVGEAVNAGSLCGLGKSAANPVLTTIKYFRDEYEAHIRDKACPACACKDLISFHIDPEKCTGCTACARACPVSAISGEKRQVHQIDQALCIRCGVCLEKCPKKWAAVSCIPGNGLGE
>NC_006138.1|WP_011187929.1|753129_753594_-|NADH-quinone-oxidoreductase-subunit-NuoE
MQNIVKTILDSYTGIDMELIPILQNVQHKFGYLPEDAMREVADFLRIPESRVYGVATFYEQFRFTPVGKTKVTVCRGTACHVRGAQKIIASVEKRLGIKEGETTEDGEYTLETAACIGCCALAPCVMINEEVEANLTPKKMNAYFDQKEEANDD
>NC_006138.1|WP_011187930.1|754022_754295_+|OadG-family-protein
MIFAGLKLMLVGMTTVLLFLIAMILLIQLISYCTRGFARKELDEIEATRRRQAEARKKKAAAKRTAVENVDEDIAVISAAVAAFEAERYA
>NC_006138.1|WP_173362837.1|754378_756145_+|biotin-attachment-protein
MDTSFRDGFQSVFGARVLTDDFMPAVKASVDAGITHIEAGGGARFQSLFFYCGESAFDMMDRFRAEVGPDVELQTLARGINVVALSQCPRDIIDLHAKMFKKHGMTTIRNFDALNDVHNLEYSGARIAHHGLKHQIVVSMMDLPPGCEGAHTAEFYMDRLKQIIAADIPFDSICFKDASGTSNPRKVYNTFKMARAIVPEGTILWFHTHDTAGLAIAQNMAAIEGGADGIDLAKSPVSGGTCQADILSQMHALKGTDYTLDLDYEKVLVASEAFELAMKDYFIPPEAKMVSPTVTLSPMPGGALTANTMMMRDTGTLHLYPQVIKEMSEVVRRGGFGTSVTPVSQFYFQQAYLNVTQGRWKKINPSYGNMVLGYFGNTPVPADPEIVALASKQLGKPVFTDDPLDILEPGIPKATKILEENNLPVSDENIFIIASCEQKGLDFLQGKAITSIRKITDEKPVAPKGKGKKAAPVAAPVGPRSYSITVNSRAYDVVVSEGGAVQASPATAAPAAAPVAVSGTEVEAPTPGNILKILVDVGDSVTENQPLLVMEAMKMESEVTAPCAGKVLAIEVATGDTVQAGTELLIIG
>NC_006138.1|WP_083819011.1|756228_757728_+|sodium-ion-translocating-decarboxylase-subunit-beta
MRFFVNVLFVLLAFCGQAVAADVVSIVSPVDATVKHVDMQIDGYVYSGDALVVLKQDDGTILSLKAGVAGKVTGVEIQAFQRVTAGQTLGRIEASAIVVDTPAVSTTSHLPSVSKLAGRLFETTGIYGFIEGQTKDWTMGIGRVLMICVGLLLIYLGIFKGFEPLLLIPIGYGAILSNIPLAGIAGPGGLLHYIYEVGIMTGVFPLIIFMGVGALTDFGPMIANPKLILLGGAAQFGIFTTLLGALFLSDMVSGINFSLRDAASIGIIGGADGPTAIFLSSKLSPRLLGSIAIAAYSYMALVPLIQPPIMRWLTTEDERQIKMVQLRHVSKIEKIILPLLVLGICVLLLPSAAPLIGMFMLGNLAKECGVIDRLSDTIKNSLMYIVTIFLGLGVGSKLSAEKFLNLETLGILALGMIAFGIGTASGLLLAKLMNKFSKTPINPLIGAAGVSAVPMAARVVNKVGLEANPQNHLLMHAMGANVSGVIGSAVAAGVLLALL
>NC_006138.1|WP_011187933.1|757844_760484_-|MCE-family-protein
MIKPATVQKEKGISAIWILPILALVICSWLLYSSYKNAGIDVTVYFDDATGIIADKTLVMTRGVRIGIVTDIDPGLEDSKIKTTVKLDRRVEEKISKDSLFWIVKPELSVTKIEGLDTIVGGSYIEVEFGKSTERGESFQGLSSSPPVNLDAPGLHITLIADSLGSIQKSTGIYSRNIEIGMVSEFKLIGEEKVSIKVFIYPQYAHLVHNESRFYNASGISIKGKLPKIKIQIESIAALIKGGIILYTPEKFIGDPPAENGQEYTFYKNFSDAEYGLEFKLHLPSNYNISEGDTKVIFHGVEVGFVKHIDTSRDQDIITATILLDPRAEVALREETVFWLVEPKVSIEGIENINTLLTGPHIAFSPGKGAFRDSFNISPVPPALIPLRRGKSFFLESAKISFIDGAAVYFKNIQVGEVVKSSLKNSGRTIHTQIYIYQKYLVLLSSKSVFWQYSGIDIQASLSGIEVKMGPIRKIISGSIAFTTPDKLKKEKNIPPKENARFPLYASRQMAVKNVAALQKPGKFFWLRTARETSLNIGSPLLHTNTAIGHIVSFKRGKNDRDIIAKCFVEKQYQGLIKPKTRFYDASGVQVSGGIGGFNIQTGPLQSIVAGGIGCFTPTEGEPKKSSAPYTLYNNFHDALYAKVNIRVLFNDLGGLKTGAPVMYKGIEIGSVTKLNLGKNLHSVSATLLVEEKTLPLFRQGTKIWLRQAQINLAEIKNLQSVILGPSVTLLPGQGEQRRYFRAIDGPPDALLTTGFPVVLEAKRLNSLTPGSPVYYRQLQVGEVVSYALAKNFENVEVRINIDDKYRNLICQKTKFWNSSGVTVKAGIFSGVTVRTESLAAFMAGGISLGNPVKKEKRKLARENQHFLLHEEGKECWQQ
>NC_006138.1|WP_162096624.1|760480_761860_-|PqiA/YebS-family-transporter-subunit
MLQLRHFIERFNEEGNGIHIGKESTVAPQRTEHLMACKDCDLLVIQAKVPPGYSAKCPRCGRCLDRSIHHSIAKVLAHSITGILLYLPAIFLPLLTFEAVGFTDSSNVIGCIIEFYQAEYYFVTLAIFLSAIVFPCLLLLSALLTSLSLYFHKYPPWLRHIFRIYVRTEEWAMTEVFFLGIIVAIIKMKDSSTIGYDAGFFCFMLVVLITVRINATMDKRLFWERIEFKDRPTEALPFSPQSRGESAAANGFCHCHDCHKLIPIADGMDKCPRCGAYLHLRKQQSISRTWALLCSAIILLFPANLLPIMQVSFMGTPTPSTIMDGIRFFFDSGQLFIGIVILTASILVPIFKVVGITILLISIKFNFHHYLRKKAIMYRYISFIGKWSMLDIFVIGLLTALVNFGFFSSVSADSAATYFCGVVLTTMAAALAFDPRLLWDKYENTAGSGPVPPQPPKTP
>NC_006138.1|WP_156792344.1|762136_763057_+|PEGA-domain-containing-protein
MVPVTTNPMGADVLVDGIASGKTPTSLDLARNQDHILTLTKSGYRQEDVTVKRVYHAEQSVLGAVSRGLSDGKFFDDANMGIQSGISSLETQKTTGEAYTLSPTAVVVTLMPVGGVVSAPVAVSGEAFAAPSAQSTLNVTEIMTSFDREMLDRALETGRSGQSVQWTNPDSGWHFVVVPHSAGRQEGMVTRDISVVGTKAGRVSKGKYPTYRENRNDWRIGYPMHTTKALEVAPVNERALLFGAAKVGASGLKPIGGEKELSHSSHSSESWGADGSHTTTTKSSSTSASVSVNPAGAIDLLEKLTE
>NC_006138.1|WP_156792197.1|763726_763903_+|hypothetical-protein
MIGLEGIAVPLGIILTLLSTLLCVAYGVVNWNRGHVTEGELAQELMWKAEEIKIKENL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_006138_1	1.1\|52278\|30\|NC_006138\|CRISPRCasFinder	52278-52307	30	NC_006138.1	50869-50898	1	0.967
NC_006138_1	1.1\|52278\|30\|NC_006138\|CRISPRCasFinder	52278-52307	30	NC_006138.1	54537-54566	1	0.967

1. spacer 1.1|52278|30|NC_006138|CRISPRCasFinder matches to position: 50869-50898, mismatch: 1, identity: 0.967

ggacagggattaaaagttaaccactgctct	CRISPR spacer
ggacagggactaaaagttaaccactgctct	Protospacer
*********.********************

2. spacer 1.1|52278|30|NC_006138|CRISPRCasFinder matches to position: 54537-54566, mismatch: 1, identity: 0.967

ggacagggattaaaagttaaccactgctct	CRISPR spacer
ggacagggactaaaagttaaccactgctct	Protospacer
*********.********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_006138_2	2.5\|198462\|34\|NC_006138\|CRISPRCasFinder,CRT	198462-198495	34	NZ_CP022748	Sphingobium hydrophobicum strain C1 plasmid p2, complete sequence	76621-76654	9	0.735
NC_006138_2	2.5\|198462\|34\|NC_006138\|CRISPRCasFinder,CRT	198462-198495	34	NZ_CP046256	Sphingobium sp. CAP-1 plasmid p3, complete sequence	158977-159010	9	0.735
NC_006138_2	2.5\|198462\|34\|NC_006138\|CRISPRCasFinder,CRT	198462-198495	34	NZ_CP032676	Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence	38471-38504	9	0.735
NC_006138_2	2.5\|198462\|34\|NC_006138\|CRISPRCasFinder,CRT	198462-198495	34	NC_014818	Asticcacaulis excentricus CB 48 plasmid pASTEX01, complete sequence	83769-83802	10	0.706
NC_006138_2	2.5\|198462\|34\|NC_006138\|CRISPRCasFinder,CRT	198462-198495	34	NZ_AP018829	Asticcacaulis excentricus strain M6 plasmid pASEM-1, complete sequence	288657-288690	10	0.706
NC_006138_2	2.18\|198462\|35\|NC_006138\|PILER-CR	198462-198496	35	NZ_CP022748	Sphingobium hydrophobicum strain C1 plasmid p2, complete sequence	76621-76655	10	0.714
NC_006138_2	2.18\|198462\|35\|NC_006138\|PILER-CR	198462-198496	35	NZ_CP046256	Sphingobium sp. CAP-1 plasmid p3, complete sequence	158976-159010	10	0.714

1. spacer 2.5|198462|34|NC_006138|CRISPRCasFinder,CRT matches to NZ_CP022748 (Sphingobium hydrophobicum strain C1 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.735

ttcccgagatcggtcaggtcatagacgccaaact---	CRISPR spacer
cgcccgagatcggtaaggtcatggacg---agttcag	Protospacer
. ************ *******.****   *..*

2. spacer 2.5|198462|34|NC_006138|CRISPRCasFinder,CRT matches to NZ_CP046256 (Sphingobium sp. CAP-1 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.735

ttcccgagatcggtcaggtcatagacgccaaact---	CRISPR spacer
cgcccgagatcggtaaggtcatggacg---agttcag	Protospacer
. ************ *******.****   *..*

3. spacer 2.5|198462|34|NC_006138|CRISPRCasFinder,CRT matches to NZ_CP032676 (Rhodococcus rhodochrous strain ATCC BAA870 plasmid pNit, complete sequence) position: , mismatch: 9, identity: 0.735

ttcccgagatcggtcaggtcatagacgccaaact	CRISPR spacer
tccccgagatcggccaggttatagacactgcgat	Protospacer
*.***********.*****.******.*.. . *

4. spacer 2.5|198462|34|NC_006138|CRISPRCasFinder,CRT matches to NC_014818 (Asticcacaulis excentricus CB 48 plasmid pASTEX01, complete sequence) position: , mismatch: 10, identity: 0.706

ttcccgagatcggtcaggtcatagacgccaaact	CRISPR spacer
gcccccagatcggtcagggcatagacctgtgtct	Protospacer
 .*** ************ ******* .  . **

5. spacer 2.5|198462|34|NC_006138|CRISPRCasFinder,CRT matches to NZ_AP018829 (Asticcacaulis excentricus strain M6 plasmid pASEM-1, complete sequence) position: , mismatch: 10, identity: 0.706

ttcccgagatcggtcaggtcatagacgccaaact	CRISPR spacer
gcccccagatcggtcagggcatagacctgcgtct	Protospacer
 .*** ************ ******* .  . **

6. spacer 2.18|198462|35|NC_006138|PILER-CR matches to NZ_CP022748 (Sphingobium hydrophobicum strain C1 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.714

ttcccgagatcggtcaggtcatagac--gccaaactg	CRISPR spacer
cgcccgagatcggtaaggtcatggacgagttcagc--	Protospacer
. ************ *******.***  *.. *.*

7. spacer 2.18|198462|35|NC_006138|PILER-CR matches to NZ_CP046256 (Sphingobium sp. CAP-1 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.714

ttcccgagatcggtcaggtcatagac--gccaaactg	CRISPR spacer
cgcccgagatcggtaaggtcatggacgagttcagc--	Protospacer
. ************ *******.***  *.. *.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

43004 : 50436

Enterobacteria_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011187288.1\|43004_44111_-	DegT/DnrJ/EryC1/StrS family aminotransferase	A0A0P0YLZ6	Yellowstone_lake_phycodnavirus	1.2e-17	26.5
WP_011187289.1\|44107_44989_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.1e-109	67.4
WP_041278134.1\|44988_46047_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	5.2e-98	51.3
WP_011187291.1\|46063_47101_-	Vi polysaccharide biosynthesis UDP-N-acetylglucosaminuronic acid C-4 epimerase TviC	A0A2K9L4U8	Tupanvirus	2.0e-70	44.2
WP_011187292.1\|47109_48390_-	Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB	M1HWZ1	Paramecium_bursaria_Chlorella_virus	2.9e-26	27.8
WP_156792160.1\|48435_50436_-	polysaccharide biosynthesis protein	A0A2P1ELS8	Moumouvirus	1.1e-21	27.6

DBSCAN-SWA_2

2285959 : 2293883

Vibrio_phage(33.33%)

terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011189246.1\|2285959_2288260_-	hypothetical protein	Q5QF74	Pseudomonas_virus	7.3e-129	37.7
WP_041277883.1\|2288260_2289847_-	hypothetical protein	A0A0H5ARR1	Pseudomonas_phage	9.6e-88	39.2
WP_011189248.1\|2289830_2290409_-\|terminase	terminase small subunit	I6PDJ6	Cronobacter_phage	4.5e-35	45.3
WP_041277884.1\|2290401_2290587_-	hypothetical protein	NA	NA	NA	NA
WP_041277885.1\|2290593_2290893_-	hypothetical protein	NA	NA	NA	NA
WP_041277886.1\|2290889_2291531_-	hypothetical protein	H8YJ90	Vibrio_phage	2.2e-11	30.9
WP_041278668.1\|2291532_2291958_-	hypothetical protein	A0A2I7QIF0	Vibrio_phage	1.2e-24	47.4
WP_011189252.1\|2292145_2292526_-	hypothetical protein	NA	NA	NA	NA
WP_011189253.1\|2292659_2293883_-	DUF3596 domain-containing protein	A0A1S5RGW8	Helicobacter_phage	1.2e-16	30.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_006139

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_006139_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006139_1

70417-70507

Orphan

Consensus_repeat	Method
GGCATTAATATTAATATCATTGCTAGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006139_1

>merge|NC_006139|1|70417-70507|CRISPRCasFinder
GGCATTAATATTAATATCATTGCTAGCGTTTAGTGTCAGATTGCCGTCGAAAGAGGCTATCTCGGCATTAATAATAATATCATTGCTAGCG

>NC_006139|1|1|70417-70507|CRISPRCasFinder
GGCATTAATATTAATATCATTGCTAGCG	TTTAGTGTCAGATTGCCGTCGAAAGAGGCTATCTC
GGCATTAATAATAATATCATTGCTAGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_006139.1\|WP_041279010.1\|49215_50067_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NC_006139.1\|WP_041279020.1\|75140_76247_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226984
NC_006139.1\|WP_011190404.1\|46707_47688_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379352
NC_006139.1\|WP_011190416.1\|72793_73684_-\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|237539
NC_006139.1\|WP_156792394.1\|77829_78846_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379352
NC_006139.1\|WP_011190413.1\|53293_55021_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NC_006139.1\|WP_011190417.1\|73702_74035_-\|conjugal-transfer-protein-TraJ	unknown	unknown	gnl\|CDD\|184361
NC_006139.1\|WP_156792389.1\|80223_80574_-\|transposase	unknown	unknown	gnl\|CDD\|376980
NC_006139.1\|WP_011190405.1\|48171_48459_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_006139.1\|WP_011190403.1\|45056_45410_-\|conjugal-transfer-protein-TraJ	unknown	unknown	gnl\|CDD\|184361
NC_006139.1\|WP_156792388.1\|50209_50404_+\|hypothetical-protein	unknown	unknown	unknown
NC_006139.1\|WP_041279059.1\|48459_48780_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|377579
NC_006139.1\|WP_041279016.1\|74150_74366_-\|hypothetical-protein	unknown	unknown	unknown
NC_006139.1\|WP_011190421.1\|76239_76926_+\|DUF4276-family-protein	unknown	unknown	gnl\|CDD\|379470
NC_006139.1\|WP_011190402.1\|44055_45060_-\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|237539
NC_006139.1\|WP_011190419.1\|74836_75094_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|213767
NC_006139.1\|WP_041279015.1\|52793_53273_-\|hypothetical-protein	unknown	unknown	unknown
NC_006139.1\|WP_011190423.1\|79177_80227_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|177883
NC_006139.1\|WP_162096680.1\|80483_81059_-\|transposase	unknown	unknown	gnl\|CDD\|376980
NC_006139.1\|WP_011190414.1\|55522_57820_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376100

Protein	Function_ID	Function_description	E-value
NC_006139.1\|WP_041279010.1\|49215_50067_+\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.24948e-06
NC_006139.1\|WP_011190404.1\|46707_47688_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	1.58335e-11
NC_006139.1\|WP_011190416.1\|72793_73684_-\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|237539	PRK13878, PRK13878, conjugal transfer relaxase TraI; Provisional.	1.5341e-40
NC_006139.1\|WP_156792394.1\|77829_78846_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379352	pfam13730, HTH_36, Helix-turn-helix domain.	2.61958e-11
NC_006139.1\|WP_011190413.1\|53293_55021_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	6.2673e-49
NC_006139.1\|WP_011190417.1\|73702_74035_-\|conjugal-transfer-protein-TraJ	gnl\|CDD\|184361	PRK13877, PRK13877, conjugal transfer transcriptional regulator TraJ.	2.30704e-13
NC_006139.1\|WP_156792389.1\|80223_80574_-\|transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	2.67038e-20
NC_006139.1\|WP_011190405.1\|48171_48459_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.10983e-09
NC_006139.1\|WP_011190403.1\|45056_45410_-\|conjugal-transfer-protein-TraJ	gnl\|CDD\|184361	PRK13877, PRK13877, conjugal transfer transcriptional regulator TraJ.	5.35895e-13
NC_006139.1\|WP_041279059.1\|48459_48780_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|377579	pfam05973, Gp49, Phage derived protein Gp49-like (DUF891). This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.	5.07163e-29
NC_006139.1\|WP_011190421.1\|76239_76926_+\|DUF4276-family-protein	gnl\|CDD\|379470	pfam14103, DUF4276, Domain of unknown function (DUF4276). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 224 amino acids in length. There is a single completely conserved residue E that may be functionally important.	9.32811e-59
NC_006139.1\|WP_011190402.1\|44055_45060_-\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|237539	PRK13878, PRK13878, conjugal transfer relaxase TraI; Provisional.	5.1065e-46
NC_006139.1\|WP_011190419.1\|74836_75094_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|213767	TIGR03070, couple_hipB, transcriptional regulator, y4mF family. Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions].	3.93582e-09
NC_006139.1\|WP_041279020.1\|75140_76247_+\|AAA-family-ATPase	gnl\|CDD\|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	3.40948e-62
NC_006139.1\|WP_011190423.1\|79177_80227_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|177883	PLN02240, PLN02240, UDP-glucose 4-epimerase.	0
NC_006139.1\|WP_162096680.1\|80483_81059_-\|transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.0202e-24
NC_006139.1\|WP_011190414.1\|55522_57820_-\|hypothetical-protein	gnl\|CDD\|376100	pfam18676, MBG_2, MBG domain (YGX type). This domain is found in a variety of bacterial extracellular proteins. This domain is related to the MBG domain (pfam17883). But it replaces the characteristic YDG motif close the N-terminus with a YGX motif.	1.10017e-12

>NC_006139.1|WP_011190414.1|55522_57820_-|hypothetical-protein
MVPAAQDKIYNQTTAVTITNANLAGILLSDDVSIATSNGNFDLKNVGHNKTVTAALTIDGADAINYTLTQPNGLTADITPAPLTVSGITASNKVYDTTTAASPITTSAIYTGLLGSDAVSVSATGFFNNKNVGIGKTVNLKSNYTGADVANYAIVDQASTTANISRADLTLSGIAVANKVYDATTATTIDTTGAAYTGLLGSDVVTVSTTGLFDNKNVGTGKVVSLYSNYEGADRDNYTITGQATATATITKATLTVNATGKDRVYNATTDASVDFVDNRFAGDVLIVSGDSAFTSKTAGRDKDILVTGMTIAGTDATNYLVAATATATADITQKELVITSISADNKIYDGTLDAVISGGSITSGILLGDHVALGTLSGSFSDKNVGIAKRVSIVGGTLSGSDADNYLVTATEITTADITPRSITITANDITRVYGNATPQYGSVSADNLAVDDLLGISLLSSDATKSSNVGTYFLSSGLASFKQGSTSNYSISYADGELLIAPRQATVTANAALKIYGNIDPSLSYDIEGQQEDRGFLGGDYLSGSLTRVVGENVGSYAIGQGTIVNDNYAIDYVAAKLTINPARLTYVADAVNRAYGTANPLLTGKVVGFKNNETLASAITGRETYSTDATINSKVGSYAIYGDGLIALNSNYIFAQDINNQNALSVFSVPNPEPFSGPSSATIFNAKELGELSDIMKMPQQTFIQSRPYFSIEFEGHAYIDGNIISMEFSPDVKIEEGVTGFGVYYLNDERNKWESGSNYLD
>NC_006139.1|WP_011190413.1|53293_55021_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MALVCYQRLLQTLTTGLLLIVIGCPATYAQDLKLVAPKKLESNAKPIEVPTDVSLQEVKSSDPQRIILKRLTGLIFLRTPEKVLKNGINMEGILTDGYMPESFFKEMNVFLNEPLSLEKLNDMLKSVVVYFRSQSTPVVDVYVPEQDITGGTIQIVVREGHVGEIRVEGNEWFESEMIAKQVRAKPGDPIRGNMLAEDINKINKNPFRRVDLVLIRGEEQGKTDVVLRTEDRFPLRLYGGYENTGTGNTGYDRYFAGLNWGNAFGLGHLLDYQFTSSDNYKSMNAHSLHYELPISYRQTINFFAAYAESNPNLDPYDLEAESFELSARYILDLDPTEKYLHSVFLGVDYKFSNSNLGFSASPVFNKDVEILQVIAGYNGSLPDGLGMTAFNLQAVVSPGNLLRYNTDEYFNNYQEGASADYLYCNLDIDRLTTLPFGFALSNKAHGQLANGQLLGSEQIGLGGYSTIRGFPEREVNIDSGLLLRNEILTPSLSLADFMNYQKDLGMLQLLAFWDYGFGRNDYIDRNETLSGYGLGLRYNFGSNISLHLDYGIQDCGKDIALGANSRLHLGLVIAY
>NC_006139.1|WP_041279015.1|52793_53273_-|hypothetical-protein
MRLGGNTIKFVSLFVAVLFLCACNPVSAEKKKEEHKTKVENPQQVEQKLVKVSTLSSVEANQEFQKNVQIMQLERQRVIQLQNQLKQAQTKDLKMSLKKEIDVAVKKINEDNNMMIKTYGFSLNRNYVLVVEKAHIYMTVSEDENKKIVAEQKTDRKKK
>NC_006139.1|WP_156792388.1|50209_50404_+|hypothetical-protein
MPTIFVLHAMGRSFPSMVSEPWATPYSTNDVAFYPSSNKRRFPEALKRVQVHTTYYKDKILKVN
>NC_006139.1|WP_041279010.1|49215_50067_+|hypothetical-protein
MATPLSMRVSEEVKESFGLLKASSGMTPEDLMLSMMENFKASRDEMNSPVSKELTKVKQVFATAERVVAAFLEIAENDKISAIDHLAAEKIVYLEAIKELKETNAELVQDKAALQAASVDQRTQLGDQVEELESIKGRLEDTSSLKEAWGKAETTYQARITELDVEAQASRQLATNKAALEKNVAELKPFQELAANFKKELGETQKQVVAHQKDIDVLQKKTNELDTKNAVLAEQKKSCEAQATTQIASLEREIALLERENQSLSGQVSLLTETLSKSNEVKK
>NC_006139.1|WP_041279059.1|48459_48780_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKWKISFYSEKVEKRTLAFSAGILANFIHIVDMMEDLGPSLGEPYTKAFGNGLFEIRARGKEGIGRSFFGTLKGREIIILHSFVKKSQKTPQKEIKVATKRLKKVK
>NC_006139.1|WP_011190405.1|48171_48459_-|helix-turn-helix-transcriptional-regulator
MRPSIKNFKKKALKKEEVKAEYERLAPVYALRKQLIKLRKDAGFTQEELAELLGTKKSNISRLENVDSKISPKISTIEKYVEKLGYRLDFTISPR
>NC_006139.1|WP_011190404.1|46707_47688_+|helix-turn-helix-domain-containing-protein
MIKRGFSNIFSEKTFASNEQFNTACRQLRITQDVQLIYSSLHWLSVKTGYAWPSQGFLANEIGRSLRTVKSHIAKLKSLGLITVKQRNNGQTALYYPLPLSEVAEHLPGCSQSQADEINGQGKETISQKGNKCTTTRHDSAHLHNIEISTSTIPPKSPPGEEAEMSFLKLWKVWPIQQAKKSARRIFMRLYRRGIIPSVEHLLKIVQNLKQYDRAWMNGKVAQLHRWLRDERWTDKAFAGLQPAPVAAPKVSKVIEPEFTPEEHRARSSYLELSVAVMTRRASTALDHITEKIVEGLGGLQGLRKKGMRCLPMADFLKAYRSLQAF
>NC_006139.1|WP_011190403.1|45056_45410_-|conjugal-transfer-protein-TraJ
MVGKKVVRNRTLKAHVTLQEYELIVKKVDYTGLTQSEFIRRALLGKRIDSMEGRQSFLDLLKVNGDLGRLGGLFKFSLSGNSPTNFDPIELRRILKEIESTQKKLIPIINKMKDSLR
>NC_006139.1|WP_011190402.1|44055_45060_-|relaxase/mobilization-nuclease-domain-containing-protein
MICKIEQAKGAKGSYRKLANYIADANNDGEKCLATWTVGGAIEDDYNLAIDEVVVTQSFNRRVQGNTYHLIISFPPEDRQKIDVEFSKKVEQNFAEILGFAEHQRHCGIHDNTSNMHIHIAYNMIDPLTKKKNSPGWDKIKCTQLCRELEIENNLKIVGSIKEKAGEQASNSKAQNVDAHAGKQSLLNYVLDRKEPLRDILERATTWQELQEGFSIYGLTIRLRGNGCVISAIGSVKQNHIKASSLGREFSKASLEKKFGEFEKRAEKYETKEKYQGEAIGKAGVDSARHERYLKKREKQRSLYQHQREKYQNAKTWNQFVYRMKRYFGSEMER
>NC_006139.1|WP_011190416.1|72793_73684_-|relaxase/mobilization-nuclease-domain-containing-protein
MICKIEQAKGAKGSYRKLANYIADANNDGEKCLATWTVGGAIEDDYNLVIDEVVVTQSFNRRVQGNTYHLIISFPPEDRQKLDVEICKKIEQNFAEILGFDEHQRHCGIHDNTSNMHIAYNMIDPLTKKKNSPGWDKIKCTQLCRELEIENNLKIVGSIKEKAGEQAVNSKAQNVDAHAGKQSLLNYVLDCKEPLRDILERATTWQELQEGFSIYGLTVRLRGNGCVISAIGSVKQNHIKASSLGREFLKAFLEKKFGEFEKRAEKYETKEKYQNARTWNQFVYRMKRYFGSEMER
>NC_006139.1|WP_011190417.1|73702_74035_-|conjugal-transfer-protein-TraJ
MVGKKVVRNRTLKAHVTLQEYELIIKKVYYTGLTQSEFIRRALLGKKIESMEGRPSFLDLLKVNGDLGRLGGLFKFYLSGNSPTNFDPIELRRVLKEIESTQKKINPYYK
>NC_006139.1|WP_041279016.1|74150_74366_-|hypothetical-protein
MAKLSFHRKKVLWRTILSGGSATKVTSFSRRKSKQIRKHKNKHIKKQNNKHKSKQENKHNSKHSASKGGGW
>NC_006139.1|WP_011190419.1|74836_75094_+|helix-turn-helix-transcriptional-regulator
MGGVKMLLVSTKEIGDALRHKRKQMGLSQSELGKRVGLDQKKVSLMENGNPNTRVESLLRLLSALELGVVLQPKADSSQNDSTDF
>NC_006139.1|WP_041279020.1|75140_76247_+|AAA-family-ATPase
MSISLDKLTIRGFKSIRELVDFELADLNVVVGGNGAGKSNLISFFKMLRALIDGNLNRYVIEHGGAGDLLFNGRKTTEKMEFETHFNSRGYRFKLIPTPKDACSLEEEARYYESGLTGWWELGDSHDGTSRMVSEVTENRSDGQYSKPIYDAISSWQIYHFHDTGSRAGMRHYEIIQDNKSLRADASNIGPFLLKLKKKHPQEYKDILNAIRLVTPFFEDFLLEPRESGNKEEVNISWRQNGSDYPMQPYHLSDGSIRFICLATALLQPMPPAAIIIDEPELGLHPAAIVILAELIQIASQKTQVIIATQSPALMDQFAIEDIIVVNREDGASTFKRLKEESFSEWLKSYSVGELWTKNVIAGGPVHE
>NC_006139.1|WP_011190421.1|76239_76926_+|DUF4276-family-protein
MSDFIEVMVIVEGKTEENFVKSLLSKYLSERNIFMSATQVTKLGQKGGDVRFERVKNDIGLHLKQRADTYVTTLVDYYGIKEWPGLDEVPPRSTPTKIAQIVNRATSDKVRALFSSLNTDRRFVPYIAIHEFEALLFSDSRILASELGISEEEVTSVLVKCSEPEAINNSPETAPSKRLDGWAKNGKFAKTSAGIAIAKIIGIAAMRDRCPVFNDWLERLEMIQRDLP
>NC_006139.1|WP_156792394.1|77829_78846_+|helix-turn-helix-domain-containing-protein
MIRRGFSNIFSEKTFASNEQFNTACRQLRITQDVQLIYSSLHWLSLKTGYAWPSQSFLANEIGRSLRTVKSHIAKLKSLGLIIVKQRNNGQTALYYPLPLSEVAAHLPGCAQSQADGVNGQGERHSVAGFISQKGNKRTATRHDSAHLHNIEISTSTIPPKSPTGEEAEISFLKLWEVWPIQQAKKSARRIFMRLYRRGIIPSVEHLLRIVQNLKKYDRAWMNGKVAQLHRWLRDERWTDKAFKGLQPAPVAAPKVSKAIEPEFTPEEHRARSSYLELSVAVMTRRASTALDHITEKIVEGLGGLQRLRKKGMTCLPMATSLKNTEAYRPLKDLGWYC
>NC_006139.1|WP_011190423.1|79177_80227_+|UDP-glucose-4-epimerase-GalE
MGTLNILVTGGAGYIGSHTCLELLEAGYEVTVVDDLSNSCYEALSRVEALTGKKITFHQVNVLDQQALDAVFVSSKKPFAAVIHFAGLKAVGESVAKPLHYYHNNVTGTLVLCDLMAKHGVKNIIFSSSATVYGDPATVPITEDFPLSCTNPYGRTKLMVEEILADLHGADHEWNACLLRYFNPVGAHKSGRIGEDPNGIPNNLMPYIAQVAIDRLDFLSIFGNDYPTVDGTGMRDYIHVVDLAKGHVCAVKKVLEGQGITTYNLGTGRGYSVLEMVSAFSRTCGRDIAYKIVARRAGDIAECYADATKALDELDWLASLGLTEMCEDTWRWQKNNPTGYLGNREVSGS
>NC_006139.1|WP_156792389.1|80223_80574_-|transposase
MDRAIGYALSQWHRLEQFIDCAAATPDNNLAENAIRPFVIGRKNWLFAGTAEGARASATIYSLIESAKVCKLEPYAYLRYLFEKLPFAENEEECRQLLPSNLSQEELEYTGRWSVI
>NC_006139.1|WP_162096680.1|80483_81059_-|transposase
MKQQFKCSKNQVVPPKPNPRWIFRGGDPTRPSMLYHYESTRSASVAATFFQGYVGTVQSDGYAGYGFLDKEQEIVHLGCWAHVRRKFHDADKARGKKAGKPGSVTMALTTYGIFLAWKRSLPMMAYLDRSLLLLEMKRAKCCFRSFMIGCSKKRTKFCQKDFWIELSAMLFPNGIGSSNLSIVQRQHQIIT

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_006139_1	1.1\|70445\|35\|NC_006139\|CRISPRCasFinder	70445-70479	35	MT104473	Pseudomonas phage MR13, complete genome	16950-16984	11	0.686
NC_006139_1	1.1\|70445\|35\|NC_006139\|CRISPRCasFinder	70445-70479	35	MT104475	Pseudomonas phage MR15, complete genome	16931-16965	11	0.686

1. spacer 1.1|70445|35|NC_006139|CRISPRCasFinder matches to MT104473 (Pseudomonas phage MR13, complete genome) position: , mismatch: 11, identity: 0.686

tttagtgtcagattgccgtcgaaagaggctatctc	CRISPR spacer
ccgtgagtcagtttgccgtcgaaagtggctacact	Protospacer
..  * ***** ************* *****. ..

2. spacer 1.1|70445|35|NC_006139|CRISPRCasFinder matches to MT104475 (Pseudomonas phage MR15, complete genome) position: , mismatch: 11, identity: 0.686

tttagtgtcagattgccgtcgaaagaggctatctc	CRISPR spacer
ccgtgagtcagtttgccgtcgaaagtggctacact	Protospacer
..  * ***** ************* *****. ..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_006140

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_006138

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_006139

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection