CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008027	Pseudomonas entomophila L48, complete genome	1 crisprs	csa3,DEDDh,cas3,DinG	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008027_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008027_1

3011730-3011811

Orphan

Consensus_repeat	Method
GGGTTTGAACTCAATGCCCAATTGATCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008027_1

>merge|NC_008027|1|3011730-3011811|CRISPRCasFinder
GGGTTTGAACTCAATGCCCAATTGATCTCTCACCACTGGCCAGCCCAGCGTGATGGGTTTGAACTCAATGCCCAATTGATCT

>NC_008027|1|1|3011730-3011811|CRISPRCasFinder
GGGTTTGAACTCAATGCCCAATTGATCT	CTCACCACTGGCCAGCCCAGCGTGAT
GGGTTTGAACTCAATGCCCAATTGATCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008027.1\|WP_011534024.1\|2993507_2995487_-\|beta-propeller-fold-lactonase-family-protein	unknown	unknown	gnl\|CDD\|274824
NC_008027.1\|WP_011534040.1\|3018546_3019758_-\|cytochrome-c	unknown	unknown	gnl\|CDD\|365823
NC_008027.1\|WP_011534030.1\|3006435_3006948_+\|hypothetical-protein	unknown	unknown	unknown
NC_008027.1\|WP_011534036.1\|3015279_3015987_-\|autoinducer-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|132580
NC_008027.1\|WP_011534041.1\|3019760_3020300_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NC_008027.1\|WP_011534039.1\|3017571_3018543_-\|XdhC-family-protein	unknown	unknown	gnl\|CDD\|224886
NC_008027.1\|WP_011534037.1\|3015992_3016847_-\|protein-deglycase-HchA	unknown	unknown	gnl\|CDD\|235228
NC_008027.1\|WP_011534025.1\|2995824_2996088_-\|DUF3077-domain-containing-protein	unknown	unknown	gnl\|CDD\|371447
NC_008027.1\|WP_044488800.1\|3014281_3015274_+\|NAD(P)H-quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|176180
NC_008027.1\|WP_044488127.1\|3024305_3026627_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NC_008027.1\|WP_011534027.1\|2996946_3002790_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|259910
NC_008027.1\|WP_044488124.1\|3013069_3013933_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_008027.1\|WP_044488118.1\|2992204_2992861_-\|SCO-family-protein	unknown	unknown	gnl\|CDD\|239266
NC_008027.1\|WP_011534042.1\|3020292_3023124_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NC_008027.1\|WP_011534026.1\|2996119_2996338_-\|hypothetical-protein	unknown	unknown	unknown
NC_008027.1\|WP_011534028.1\|3002938_3005029_-\|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl\|CDD\|236645
NC_008027.1\|WP_011534031.1\|3007457_3008654_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_008027.1\|WP_011534023.1\|2992857_2993511_-\|SCO-family-protein	unknown	unknown	gnl\|CDD\|239266
NC_008027.1\|WP_011534038.1\|3017011_3017575_-\|nucleotidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133025
NC_008027.1\|WP_158020256.1\|2990570_2992199_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|379197

Protein	Function_ID	Function_description	E-value
NC_008027.1\|WP_011534024.1\|2993507_2995487_-\|beta-propeller-fold-lactonase-family-protein	gnl\|CDD\|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	1.05362e-21
NC_008027.1\|WP_011534040.1\|3018546_3019758_-\|cytochrome-c	gnl\|CDD\|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	3.78036e-09
NC_008027.1\|WP_011534041.1\|3019760_3020300_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.19042e-55
NC_008027.1\|WP_011534039.1\|3017571_3018543_-\|XdhC-family-protein	gnl\|CDD\|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	2.05981e-56
NC_008027.1\|WP_011534037.1\|3015992_3016847_-\|protein-deglycase-HchA	gnl\|CDD\|235228	PRK04155, PRK04155, protein deglycase HchA.	0
NC_008027.1\|WP_011534025.1\|2995824_2996088_-\|DUF3077-domain-containing-protein	gnl\|CDD\|371447	pfam11275, DUF3077, Protein of unknown function (DUF3077). This family of proteins with unknown function appears to be restricted to Gammaproteobacteria.	1.88175e-16
NC_008027.1\|WP_044488127.1\|3024305_3026627_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	7.80227e-96
NC_008027.1\|WP_011534027.1\|2996946_3002790_-\|hypothetical-protein	gnl\|CDD\|259910	cd11024, CuRO_1_2DMCO_NIR_like, The cupredoxin domain 1 of a two-domain laccase related to nitrite reductase. The two-domain laccase (small laccase) in this family differs significantly from all laccases. It resembles the two domain nitrite reductase in both sequence and structure. It consists of two cupredoxin domains and forms trimers and hence resembles the quaternary structure of nitrite reductases more than that of large laccases. There are three trinuclear copper clusters in the enzyme localized between domains 1 and 2 of each pair of neighbor chains. Three copper ions of type 1 lie close to one another near the surface of the central part of the trimer, and, effectively, a trimeric substrate binding site is formed in their vicinity. Laccase is a blue multi-copper enzyme that catalyzes the oxidation of a variety of organic substrates coupled to the reduction of molecular oxygen to water. It displays broad substrate specificity, catalyzing the oxidation of a wide variety of aromatic, notably phenolic, and inorganic substances. Laccase has been implicated in a wide spectrum of biological activities.	0.000123643
NC_008027.1\|WP_044488124.1\|3013069_3013933_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.05521e-35
NC_008027.1\|WP_044488118.1\|2992204_2992861_-\|SCO-family-protein	gnl\|CDD\|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	1.23995e-33
NC_008027.1\|WP_011534028.1\|3002938_3005029_-\|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	7.22491e-124
NC_008027.1\|WP_011534042.1\|3020292_3023124_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	3.61342e-71
NC_008027.1\|WP_044488800.1\|3014281_3015274_+\|NAD(P)H-quinone-oxidoreductase	gnl\|CDD\|176180	cd05276, p53_inducible_oxidoreductase, PIG3 p53-inducible quinone oxidoreductase. PIG3 p53-inducible quinone oxidoreductase, a medium chain dehydrogenase/reductase family member, acts in the apoptotic pathway. PIG3 reduces ortho-quinones, but its apoptotic activity has been attributed to oxidative stress generation, since overexpression of PIG3 accumulates reactive oxygen species. PIG3 resembles the MDR family member quinone reductases, which catalyze the reduction of quinone to hydroxyquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	3.55634e-177
NC_008027.1\|WP_011534036.1\|3015279_3015987_-\|autoinducer-binding-domain-containing-protein	gnl\|CDD\|132580	TIGR03541, reg_near_HchA, LuxR family transcriptional regulatory, chaperone HchA-associated. Members of this protein family belong to the LuxR transcriptional regulator family, and contain both autoinducer binding (pfam03472) and transcriptional regulator (pfam00196) domains. Members, however, occur only in a few members of the Gammaproteobacteria that have the chaperone/aminopeptidase HchA, and are always encoded by the adjacent gene.	4.06878e-139
NC_008027.1\|WP_011534031.1\|3007457_3008654_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.5099e-140
NC_008027.1\|WP_011534023.1\|2992857_2993511_-\|SCO-family-protein	gnl\|CDD\|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	2.40948e-39
NC_008027.1\|WP_011534038.1\|3017011_3017575_-\|nucleotidyltransferase-family-protein	gnl\|CDD\|133025	cd04182, GT_2_like_f, GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	9.97668e-60
NC_008027.1\|WP_158020256.1\|2990570_2992199_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|379197	pfam13458, Peripla_BP_6, Periplasmic binding protein. This family includes a diverse range of periplasmic binding proteins.	1.13062e-26

>NC_008027.1|WP_011534031.1|3007457_3008654_+|IS256-family-transposase
MTKPTIALTELVEKGADADLLKQMIQFVAQRMMEFDVESLCGAGFDVKSPDRTTSRNGYRDRLWQTRAGDVDLKIPKLRQGSYFPGFLEPRRTAEKAMAAVIQEAYIQGVSTRSVDELVKAMGMTGISKSQVSRLAGEIDERVHAFLDRPLEGDWPYLWIDATYVKVREAGRIVSVAVIIAVAVNTDGGREVLGMRVGPSEAEPFWTDFLRSLMRRGLRGVKLVISDAHEGLKAAVSKVFNATWQHCRVHFMRNAMAHVGKGQRTMVAALLRTVFAQDSRAECHQQWRLVADQLREKYPKIATLMDGCEDEMLAHMAFPKAHRQQLHSTNPLERLNAEIKRRTDVVGIFPNDPAITRLVGAMLLEQNDEWCLQRRYMQLEAFEAVSDNPQAKLSAVIN
>NC_008027.1|WP_011534030.1|3006435_3006948_+|hypothetical-protein
MSNESSATNIPQDAETTEPIRWGFIKDHTFIQPETIIPCTLAIKSIGRTDMLLAAYGKRYLRYENAGRFYNYNITMASIDIEIPEHLLETARLAVSLLSDGRRYSSLFQMTFKSGKLYTAKYIMTGTIPNISPPELQCPFTTRTTSDMPPDCQRCTSMYWLLRERCGCNA
>NC_008027.1|WP_011534028.1|3002938_3005029_-|bifunctional-diguanylate-cyclase/phosphodiesterase
MLIGSYSSSLVLISLCVAILASYTALDLTGRIATAKGRAVHLWMLGGAFAMGIGIWSMHFIGMLAFSLPINLGYDTTLTALSLLIAVASSGFALWLVSQPKLPWQQLGFGALIMGSGIACMHYTGMAALRMQPGIDYDPTLFGASLAIAVGASAAALWIAFRLRQHTPYVRQFRGLAAVVMGIAIVGMHYTGMAAANFPTGSYCGALVDGLAGDGLDYLVLITTLAVLSVALLTSVLDARLEARTAELARSLTLANQELTQLALHDTLTGLPNRTLLADRIDQAIGRVAEQGGCFALMFIDLDGFKPVNDAFGHHVGDLLLKAVAARLRGHLHSQDTLARIGGDEFVLLVELGEPDDAMGVAVKQVNLVSRPFRVAEHDLQLTASLGIVLYPGNGADQHELLRNADAAMYHAKSAGKNGYSFFDASMNTNARQQLQLLQDLRTALEQGQFRLHYQPKFDAAARQPIGAEALLRWEHPQHGLMLPDRFIGLAEKTGLIIPIGEWVLGEACRQMRQWMDQGHDDWRIAVNLSAIQFCHAGLVDSVARALNDNGLPANRLTLEITETTAMRDADASLTVLQRLSDMGVDLSIDDFGTGYSSLMYLKRLPANELKIDRGFVRDLEQDSDDAAIVSAIVALGQALGLRIVAEGVETDRQQDFLTRLGCDSLQGYLLGQPVPPEQFMQRLEQAGKGAGQTVG
>NC_008027.1|WP_011534027.1|2996946_3002790_-|hypothetical-protein
MSTPRKGPVLSTLLLALLGWQASGEAAVQCQRTLTANVVALDQPLMFNRLGAQNANGMMFALRQDVVDEHQVPLNKGGAAVPGKVTLRPDKRPRPIVLRVAAGDCLTVNLTNLLAYQANPNKHGIHPEEPEGEEGEEAEVPEVEDDENFVADQQVTDRHTGFQVNGLQAVNSIADIAANTGRNGNFLVAPGSTRSYTLYAEREGAFAVSSRGAPFGGEGNAGNVANGLFGQVVVVPKGGRTYRNTLTEEEMRLATTGRTATGQPVIDYEARYPQAEPWIAEGKAGKPIIAMIDGNEILNSETDAIVMGPNPDGSFPKATYPLESVGKRNPALPNRLEAFRDFAAQFADEVAGTQAFPGYWADPVMGHVLEPARDSFMINYAAGGMGAEVVANRLGVGPMHDCLSCAYEEFFLSSHTVGDIGTLVDIPANVGLERIRPGEVPPASATGVKATMALYPAEPANVHHSYIGDFTKFRNTHNGHEQHIFHLHGHQWLFNPNDDNSDYIDAQGIGPGVGYTYEIANGGSGNRNRVAGDAIYHCHFYPHFAQGMWAMWRVHDVFEPGTRLEVSGEGANGYHSTPFALRNGKPAAGARALPDGEIVAGTPIPAIVPLPGKAMAPMPGKVTVVPKLSETLVAEHDDDEEEGDDHPDEPATPRAVGSLALVDRSETNRNADGSLKNPGYPFWIGGMESSVGQRPPTPPLDMLDPALARQLKDSGKALWANLDPNQVDGWDGGLGRHALDGVSAGGEAVTTTTKLDFSKVVHKAKPIYLPEEGTEVEQAAMQFHAKAEHPSFALIPGSAPVAKAFRTNGALPTAGAPYYEPCMDDRGKRLTQSSGVGEFFSGENLTGMSFRGSSTFTADRPRIYKAANIQFDAVYNKVGYHFPQARILALWEDAWPVITKQRPPEPMVLRMNTFDCTQYVHTNLIPSFYEMDDYQVRTPTDVIGQHIHLPKWDLTAADGSANGWNYEDGILSPGSVVERVHAIRAFNNCSEGDARDGTAACPKAKQHPYFGRFGRADWLGARTAMQRWFADPLVNVHNVDRGLGTIFTHDHLGPSTHQQLGLYATVLAEPAGSTWYHAETGEQLYNPATRQDGGPTSWQAVIQTGDHDGDGKNDSYREFFLEYSDFQHAYEAGVYVGAGPNGIPDGQSYPATADSFRYAINPPVRGKASNLLEAIVETRGGLNPGCPSRPCPQAISVDDPGMFVVNYRNEPLALRVFDPNKVGPDGKRGMQADGLGGDLGYALQTRTDRAIPAMNLAPSAITQAVGPTGGTTLFPPHINKAGSEPGDPFTPMLRTYSGDNVRLRMHAGGHEEEHNVTLHGVKWLQNGSGFGNSSNSGWKSSQMIGISEQLGFMAPVSMISSSAATNGDYLYSLDAALEGYWNGIWGIMRNYTAQRSDLFPLPNNPQPVAMRNTVNFDGICPKTTANPTGVGTRPTVKRSYEVVAALANDILENRQGVSISDPAGIGQHVGGPLKANGGTLVFNSRRTSIPLVSGVDPEDGETFTIGGHSAPLHDPTAILYVRKADLDASTGKLKAGVPVEPLILRANAGDCISITLENRLPLVMPDLPSTAVMHNVVKRDRFDSEGATAFANNLMRPSSHVGLHAQLLAYDITKSDGVNVGLNPVQTVPPRSGSSGAWPTKVYQYYAGHLEREGKPTLQLGRTVDNINTTAIEFGGLNLTPADVIKQPQKGLVGGMSILPQAATWTEDTASRAQATVKVSGQPDYRDFVTVWQRALNMRWADGRPVAGINTEGNGAAGDPQDNGNMAVNYKTEPLWLRFGVAPDAPFGRADGLGFADIPNVHMAYSNALVGGDPQTPVLYAKPGQPVRNHIVMPSGGSRGMTYQLDGHVWPLHNFQAEKSDVDGYPMGLPGIGSVRFGYNPMAMFIGAQESVLPAAHFSFMLPSAGGANAVPGDYLFRDYAAYGNTSGLWGILRVTNEAPPAVAPAQ
>NC_008027.1|WP_011534026.1|2996119_2996338_-|hypothetical-protein
MLKIVPDPPTVLEDTLVQTSEHVRCALAVAQQSIPLISRSPGSMLVLAALHEMETVKALLDSALAQVQATLH
>NC_008027.1|WP_011534025.1|2995824_2996088_-|DUF3077-domain-containing-protein
MTPEDPNTTVGQTRFYQGENNTQPLFCIEPGIPCRHAREQSSELMDCVRHLTLVGVMENDQRMVWAAHYLSALAKALMDDAELGMAH
>NC_008027.1|WP_011534024.1|2993507_2995487_-|beta-propeller-fold-lactonase-family-protein
MSGKVRPAYLGLLVGLALLGLGVAYEKLWCDPRELLQETADPSAEHRLSRDGVTVEFEASPLAGSELREGDFANIRFKVSDQSSGQPLSGMAPGAWLDPAQSAPPGDRDSSCKARVALFLKSSIGARPLLDLNSYFLLVLNKDASLTVIDPTVSVGGVTSTLARIDLPGRPMDWVATGDDKQVFVSMPERGQVALIDTETFRRVAILEAGAQPLRVALQPDQRLLWVGNNSDDPAKGGVTVIDVPSRTTLKSFSTGSGHHEIAFSADSRYAFVSNRDAGTLSVIDITEMRLAKTLEVGPQPLSVTYSPLSQAVYVVDGQEGTVRVIDARSHQPRHTVKAEQGLGPMRFSGDGRFGVVLNTLENQALVIDASTDQLIHRIPVAAEPYQLTFTKAYAYVRGLASPKVSMINLASLGQGRTPIVQGFEAGPAAPRQAGDLPLAQGLSVSRDDNAVFVVNPVDNTTYFYAEGMNAPMSGYNNRGHQARAAIVIDRSLREVAPGVYGSTVRLPAAGTFDVAFLLNQPQIIHCFSTVVAALPQASGHKAARAEFIGIDRPLLQHSPFMARVRILGEDGKPRTGLGDLSLRYFLAPSSLPRNLPLNEVGEGEYQAALTLPEAGAWYLHVQSPSLGRKFAEENYTSLRVLPAAAAPTASQGEPRSVR
>NC_008027.1|WP_011534023.1|2992857_2993511_-|SCO-family-protein
MNTNSPRQLIALSLLLASQLTLAHGGHDHGGPPAPPPAAHQEKASVRFADVSLLDQDGMPVRLEKDLVGDRLVVMGFIYTSCTTVCPVVSSIMGKVQQQLGGRVGEEIRLVSISVDPQRDDAKRLASYARAFQHGPGWSWLTGSPYAISETLKGLGSFSANLSEHPPLILVGDGRTGHWTRYYGFTDPNVLITELNRLSARRVHAKTTAIAGQEVQP
>NC_008027.1|WP_044488118.1|2992204_2992861_-|SCO-family-protein
MSSLSPRPAGMRSFDWVVLVACLWILASVAYAHEGHAPTPQPAPQAMASGGGTRDAQTWFTDTVLKDQNGRELRFYSDVLKDKVVMLNVMFTHCNDACPLITRKLREVREAMGAELAAQVTFVSVSSDPLNDTPEALKAFAVKQGVDGPNWVFLTGDKASVDLVLGRLGQFLPSPEQHSTQLIAGDVAGKRWSKIRPDAPPAAIAQRMQLLAQPLAGR
>NC_008027.1|WP_158020256.1|2990570_2992199_-|ABC-transporter-substrate-binding-protein
MNRRGSGRHAGCGRKGLVLAALAHSPAKPAPTGGLAGIRALCCYWMALCLMLCNTAQALDLTAQELAGKRLYREGLSSSDAQLLARVGASDMTVPASVLPCASCHGNDGRGRSEGGVRPPSLDWQHLALGPGARETNNRRYPAYTEASLARVIHSGIDPAGNRLDPAMPRFDLSLADQRNLTAYLKRLGEERDPGVEEGVLRLGTLLPENGPLAEAGRVVRAVLEDGAAQINQQGGVHGRRLQLVALDPGYDPASTGQALDRLLRQEQVFALIAPLAAQLDSATLAREGVPLVGSTPRDGGSAQVFDPLPSLPEQLLSLAVHARDGLGMPAAALQVVYAGEDQAAAANALLIRLRSLGFALPEAQVFNGQAPSGEGIVFLGPAPVFAELAATLQAQGRTPYLFAASSQIASVVPTLSAQWSQRLLLAYPFVPGDWTDTGQATLAGIRQRQGLDARQASLQIGTLCAWQLMTEALKTIGRDASREQLIATLEQLHAVDTGLTPPLGFGPGRRQGMAGAHVVEVSLPGPGFTEVAPYRPVPEAP
>NC_008027.1|WP_044488124.1|3013069_3013933_-|LysR-family-transcriptional-regulator
MNWDDARMLLALSREQTLRRAARVLRVDQATVGRRVAALEADLGSTLFLRTPAGYQLTALGEVAVEMALKMEQAALELTRRIGGADNELAGEVRIATTDSLAQDFVIPALAQLHREHPGIRVVLSGSSEIVNLSQRETDIAIRNLRPDNPDLVLRKLASWTMGLFASADYVQRRGMPAVGNFEGHELVVYEPYWRDQARPTLVDVPIGEGRVVLAANASLMLRRAIGQGLGIGEIPVELGLLDGLQRIWPECTRAKPYEVWMVTHQDLRHTARVRVVIDHLVRAFAA
>NC_008027.1|WP_044488800.1|3014281_3015274_+|NAD(P)H-quinone-oxidoreductase
MTAIDITQPGGPEVLLPTTRDTPRPGPREVLVQVHAAGVNGPDLLQRKGLYAPPPGASDIPGLEIAGRVVALGEQVSRFVVGDAVIALVPGGGYAEYAVADERTTAPLPANLSMVEGAALPETFMTVWVNLFQRGGFKAGESVLIHGGASGIGTTATQLAKAFGASKIFTTVKDAEQQAASLALGADVAVDYTREDFVEHVMQHTNGQGVDVIVDIIAGDYVARNFKAAAMDGRIVQIGVVKGPASEVDLFPLLVKRLTHIGSTLRARSIDDKAAILDDLQARVWPHVCGGSVKPLIHATFPLTAARQAHELMESGRHIGKVVLSLAYQG
>NC_008027.1|WP_011534036.1|3015279_3015987_-|autoinducer-binding-domain-containing-protein
MPFDKVVQAVQQIEQATTLALIQSAVRSVARPLGYDRFVLFSANAARDEVVERIHWVEGDWFGDGLRVDAQTYIRHCPVNRHLLTAREPFFWSKREGEGGERYHVVRAPVGTGVHGLQVPVFGPAGLEGAMSLGGLHIDASPATRMCLALLANAAFHAARRLLEAPVGQEVGVLSERERQVLAWTAAGQRQADIAATLGLSVRTVENHLRAARRRLGVATTAQAIRIALGSGVLG
>NC_008027.1|WP_011534037.1|3015992_3016847_-|protein-deglycase-HchA
MTNTNDEKRPTPDPAEDNAFFPSPYSLSQFTSSKSDLSDANYPEPYEGGRWKILLIGADERYLLTDNGTLFSTGNHPVETLLPMYHLDKAGFAFDVATLSGNPVKFEYWAMPSEDTEVLGLFDRYRKAFKQPRKLADVLENALGDGSDYLGVFIPGGHGALIGLPESKEVGQVLQWAADNDKFVITLCHGPAALLASGRLYDGYKICAFPDELDAKTPDIGYMPGHLAWKFGERLQAQGVEIINQGISGAVHQDRKLLTGDSPLAGNALGKLAAATLLKAVNAG
>NC_008027.1|WP_011534038.1|3017011_3017575_-|nucleotidyltransferase-family-protein
MSVVALVLAAGQGSRFGGDKRRALLADGRSLLQHSVERALAVFDEVRVVLRAGERAEDLGLPTGCRIVVSPEAGLGMGHSLAAGAASLDNCAAEAVSIVLGDMPWIQARTFRRLIEAASPTAIVVPCHHQQNGHPVLFGRTYWPELTVLAGDQGARSVLQRHRQQMLVVEVDDAGVLRDVDTPAALG
>NC_008027.1|WP_011534039.1|3017571_3018543_-|XdhC-family-protein
MQHLDLQVVQQAAQWSRDGLRVWLCTVLGTYGSAPRAPGSLLAVNGQGHWVGSLSGGCVEEDFLERVAAGEFAEAVAVVRYGDASDSRSNIRLPCGGILDVLVENLPGDCATQAHLGELEAALLGRRRLLREVDLRTGQRLVCDDHSHGLRVEQGEGRVRLRVGAAQRLLLAGYSSVAHFCAEFGKGLGFEVVLCDPRDEVMDNVVLDGIEIRRELPSVFIANGGCHRDTAVVALTHDPKIDDLAMLEAVQTEAFYIGVMGSRATSEKRRERLRRIGGLNDAEMTRIHAPIGLNLGSKTPAEIALAVLADILRTRSGVAREAL
>NC_008027.1|WP_011534040.1|3018546_3019758_-|cytochrome-c
MKQVLSGLAIAIGAVLAFSAQADDQAQVKRGEYLARAADCMACHTAEGGAPYAGGLPIHSPFGTIYGTNITPDKQYGIGNYSDDEFFAALTAGKRKDGANLYPAMPYTSYHLIPREDADAIHAYLKTVAPINRPAPETSLSFPFNVRLGLMGWNMLYGKSVQLEEGKGNSEAWKRGQYMVEVLGHCGECHTPRNPIGALQQDKRLTGGLLQGYLAPSLLAQDLADRGWNHADLATFLKHGMSAQGSMFNEMYPVVHHSTQHLEDSDLSAMATYLLGDQPPAAKVVQAVAHETLGESAKRGRQQYLNVCAGCHGGEGEGKPHIAVAMAGNTILRQADSRNLVKAIVDGIREQQFTGFERMQPMPGFADKLDDQQLTDMVNYLREAWGGLPGDLTTQQLAQLKAD
>NC_008027.1|WP_011534041.1|3019760_3020300_-|(2Fe-2S)-binding-protein
MADRKLQLTLNGQPVVTEVVPDDLAMIDYLHEYQNLTGSRLGCGQGICHACVVIVDNPDGTSEEVRTCITGAHYFEGKKVRTIEGHAKLDEAGNPGELNPIQQKFVDRFAFQCSYCAPGFVNAATVLVEKAQRKPLRKSELEDAIEASLGHHVCRCTGYVRYYEATREVLGDLGLVKEG
>NC_008027.1|WP_011534042.1|3020292_3023124_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MSNRDISRRSFLQGGLIAGVGVTLAPLGSQAFAALMENKVTTSPQKWMNHDGKARLRNDALSKVCGNKVFARDIRAKDMPGWPQQQGHAMLLKATKADQIYAGYDLSLLGADLQPDRIVTADDLKKDGIAWPEAHSPDPLLPPGQVPMFIGHPVAILIWNDFERFRKAKLKLQFNDKAIRYGAQAPLYQRDPYGSFRFVRVGGKTPFDEDEYSSLKNTMLFPTILARKPVWTAEPKQHGTLTEQGMFYAQRIDEQLKQPPEDWLLFDERYKTPSIEPAALEPDNGNGWYDPATGTLHFVVATQCPFEVAQECVHMIKPSRFGLKHLNMHPGYTVGYGSKDNNIFVFYAAVAALYGAGVPIRLANDRYEQFQSGIKRHPFDIRYQLAVDKRDMSFKIFRADMTVDGGGRINYSPSVAAVGATAAQSIYYMPQNDLSVTAYHSRGVEAGSMRGYGTLQSMAATEMMVDEIADRLGVDAIELRRKNALKSGMKNTQGAVPAGALRLHEILDKAAEHDWWKNRHARKQAEDAKDHDNWYGVGFAITQKDFGTGSEAPMAAVEFTADGRITLRHIGTELGTGMSTSQALVVSDFLGRVADEVKTAQTEWPELQLSTSGNPYLISQAEQDAALRNPRWVGKLASPSSATNSAFYFSHATREAARVLFNHGLWPAAMALWSQGPYGGQANPLVVRRENAVWVNGALTGNGLAPIPFAELAKKAHEMGLVTGVSVHGFNRWSWAEADFVIDGVRERLPLDALAVKYGDGALNAKKAQMNSNGFHLLDRQNAEYPATQLNNAMVTYYSPVATIVEVKVNKGSGEVTVLNHHSWVECGRVLVPELVKGQLEGGIAMGIGHALLEEMPLYEGGPGEGDWNFNRYRLPMAKHVAVWKQTSEILPPLSPTDPSKGIAEVVMIPVVGAIGNAVAHAIGKRVRDLPITPARVKEALNG
>NC_008027.1|WP_044488127.1|3024305_3026627_+|EAL-domain-containing-protein
MIRRPLSPAGLLPLLLMTLCAVTLTFLWGLHISQKTASRQDALAAKALEHLNLASIVAENLRQLVDRAQAVGRVTQDDMRRLRQGNLSLARVLAEDPVFKRMSLYDRNGRLLSSSHADEPEQLSQAWLDQLKTHVSHYGFKAFLPRVTPSASTLPNWRLPFLLPLTDLPGREIDSILVVQLDIGYLAVLFQHIELGHSGLVRLLQDDGQERLRIDTSGVVVAGDTLVPGLPGTGDEAGQLTQYTLAGPYQSLYRRVPERGFSVVVSQRHDEILAPALLASHRQFWLNLSMTLLILASLAWGLRLLRKRHEAFRELQHAQRVNQQLIDRLEEAHRRSSHAAATDHLSGLHNRRQFVEIATQALAHQRGRRRLMAILFIDMDRFKSINDSLGHKVGDLLLQAVAGRIQRLLEPDDEASRFGGDEFVVLLAGERGEEQIDAWVRMLVEKLSATYALAGQEVNTSPSVGVSICPRDGQDIDTLIRSADAAMYSAKQAGRAQYRFFDPSLNLPDIQAFTLEQAFGGALVERQFVLHFQPQIRLDTLQVHSYEALVRWQHPEFGLLYPDRFIGVAERSGFIVELGWEVLRLACEELARWRLRDHSACLAVNVSALQLRQADFSERLLAELDSYGIAPQRLELEITETTVLDPQGCAVEHLHRLRAAGLGISLDDFGRGYAGFAHLQSLPLSKLKIDRALIAPLCNSHDDSPIVSSTIILAKRLGLEVVAEGVETREQVVCLKLAGCDIAQGYHFSRPLSPAQLHDYPPFNGTEEKACVY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1144394 : 1152147

Thermobifida_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011532413.1\|1144394_1145249_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	2.0e-07	31.0
WP_011532414.1\|1145251_1145716_-	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_011532415.1\|1145728_1146037_-	ribosome-associated translation inhibitor RaiA	A0A0K1LP60	Escherichia_phage	1.1e-05	35.2
WP_011532416.1\|1146115_1147612_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_011532417.1\|1147784_1148510_-	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.4e-23	26.5
WP_011532418.1\|1148510_1149035_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_011532419.1\|1149021_1149594_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_011532420.1\|1149602_1150127_-	HAD family hydrolase	A0A140XBD6	Dickeya_phage	1.4e-27	48.1
WP_011532421.1\|1150127_1151102_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	6.8e-36	32.8
WP_011532422.1\|1151337_1152147_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.0e-24	32.1

DBSCAN-SWA_2

2328838 : 2339737

uncultured_Caudovirales_phage(70.0%)

integrase,tRNA

attL 2331279:2331295|attR 2342681:2342697

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011533437.1\|2328838_2330119_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.2e-96	54.1
WP_011533438.1\|2330119_2331511_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
2331279:2331295	attL	NA	NA	NA	NA
WP_011533439.1\|2331616_2332576_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_011533440.1\|2332672_2333674_-	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	5.9e-152	79.6
WP_011533441.1\|2333670_2334006_-	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	5.7e-43	75.7
WP_011533442.1\|2334002_2334299_-	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	2.3e-27	64.6
WP_044487975.1\|2334298_2334658_-	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	3.3e-36	65.0
WP_011533444.1\|2334659_2335052_-	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	6.5e-54	79.1
WP_011533445.1\|2335139_2336519_-	uracil-xanthine permease	H9YQ34	environmental_Halophage	7.4e-28	53.0
WP_011533446.1\|2336727_2337399_-	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	5.6e-106	91.0
WP_011533447.1\|2337756_2338806_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JDJ8	uncultured_Caudovirales_phage	4.7e-107	60.3
WP_011533448.1\|2338807_2339053_-	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_044487978.1\|2339089_2339737_-	hypothetical protein	A0A0U4JX72	Pseudomonas_phage	4.8e-62	53.0
2342681:2342697	attR	NA	NA	NA	NA

DBSCAN-SWA_3

4381001 : 4484094

115

Pseudomonas_phage(41.67%)

tail,bacteriocin,plate,lysis,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044488353.1\|4381001_4381199_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_011535149.1\|4381459_4382134_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	2.1e-28	38.2
WP_011535150.1\|4382144_4382792_-	7-carboxy-7-deazaguanine synthase QueE	NA	NA	NA	NA
WP_011535151.1\|4382952_4383762_-	tol-pal system protein YbgF	NA	NA	NA	NA
WP_011535152.1\|4383768_4384266_-	peptidoglycan-associated lipoprotein Pal	NA	NA	NA	NA
WP_011535153.1\|4384319_4385621_-	Tol-Pal system protein TolB	NA	NA	NA	NA
WP_011535154.1\|4385617_4386694_-	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_011535155.1\|4386693_4387146_-	protein TolR	NA	NA	NA	NA
WP_011535156.1\|4387160_4387856_-	protein TolQ	NA	NA	NA	NA
WP_011535157.1\|4387858_4388311_-	tol-pal system-associated acyl-CoA thioesterase	NA	NA	NA	NA
WP_011535158.1\|4388436_4389483_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.0e-05	27.4
WP_011535159.1\|4389479_4390097_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_011535160.1\|4390205_4390730_-	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
WP_011535161.1\|4390852_4391605_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_011535162.1\|4391716_4393492_-\|tRNA	aspartate--tRNA ligase	A0A1V0SIS0	Klosneuvirus	5.6e-12	26.3
WP_003254776.1\|4393586_4393808_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_044488870.1\|4393900_4394218_-	ribbon-helix-helix domain-containing protein	NA	NA	NA	NA
WP_011535164.1\|4394423_4394897_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	3.1e-18	36.4
WP_011535165.1\|4395142_4395733_+	cold shock domain-containing protein	A0A1X9IGI9	Lactococcus_phage	1.7e-10	48.3
WP_011535166.1\|4395752_4395959_-	protein SlyX	NA	NA	NA	NA
WP_011535167.1\|4395962_4396382_-	HIT domain-containing protein	NA	NA	NA	NA
WP_011535168.1\|4397157_4398474_+	OprD family porin	NA	NA	NA	NA
WP_011535169.1\|4398631_4400347_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_011535170.1\|4400368_4401322_+	hypothetical protein	NA	NA	NA	NA
WP_162042958.1\|4401352_4402411_-	DNA polymerase IV	NA	NA	NA	NA
WP_011535172.1\|4403388_4406031_+	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
WP_011535173.1\|4406030_4407323_+	virulence factor family protein	NA	NA	NA	NA
WP_011535174.1\|4407410_4409321_-	potassium transporter Kup	M1HZV6	Acanthocystis_turfacea_Chlorella_virus	1.2e-76	34.1
WP_011535175.1\|4409557_4410889_+	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_044488358.1\|4410974_4411433_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011535177.1\|4411554_4412265_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_011535178.1\|4412315_4412777_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.7e-37	50.7
WP_011535179.1\|4412783_4413479_+\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_011535180.1\|4413614_4414394_-	ferredoxin--NADP reductase	NA	NA	NA	NA
WP_011535181.1\|4414514_4415441_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011535182.1\|4415444_4415810_-	diacylglycerol kinase	NA	NA	NA	NA
WP_011535183.1\|4415885_4416536_-	response regulator transcription factor	NA	NA	NA	NA
WP_011535184.1\|4416792_4417503_-	DTW domain-containing protein	NA	NA	NA	NA
WP_011535185.1\|4417717_4418140_+	quorum-sensing-regulated virulence factor family protein	NA	NA	NA	NA
WP_044488360.1\|4418141_4418348_-	hypothetical protein	NA	NA	NA	NA
WP_011535187.1\|4418653_4419772_+	LOG family protein	NA	NA	NA	NA
WP_011535188.1\|4419824_4420292_-	recombination regulator RecX	NA	NA	NA	NA
WP_011535189.1\|4420300_4421368_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	2.2e-112	62.3
WP_011535190.1\|4421472_4421955_-	CinA family protein	B5TK85	Pseudomonas_phage	6.3e-59	76.7
WP_044488362.1\|4421996_4422494_-\|lysis	lysis protein	B5TK84	Pseudomonas_phage	2.0e-36	59.1
WP_011535192.1\|4422490_4423042_-	glycoside hydrolase family 19 protein	B5TK83	Pseudomonas_phage	1.3e-71	69.4
WP_011535193.1\|4423028_4423238_-	Com family DNA-binding transcriptional regulator	B5TK59	Pseudomonas_phage	3.7e-08	68.4
WP_011535194.1\|4423415_4423799_-\|tail	tail protein	NA	NA	NA	NA
WP_044488363.1\|4423808_4425026_-	hypothetical protein	B5TK77	Pseudomonas_phage	1.3e-20	69.6
WP_044488366.1\|4425037_4425637_-	DUF2313 domain-containing protein	B5TK76	Pseudomonas_phage	3.2e-84	74.9
WP_011535197.1\|4425624_4426665_-\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	2.9e-133	68.2
WP_011535198.1\|4426654_4427053_-	phage GP46 family protein	B5TK74	Pseudomonas_phage	2.7e-47	67.4
WP_011535199.1\|4427049_4427550_-\|plate	phage baseplate assembly protein	B5TK73	Pseudomonas_phage	6.5e-67	74.7
WP_011535200.1\|4427575_4428631_-	hypothetical protein	B5TK72	Pseudomonas_phage	1.8e-98	52.8
WP_011535201.1\|4428634_4429936_-	DNA circularization N-terminal domain-containing protein	B5TK71	Pseudomonas_phage	3.6e-101	48.0
WP_011535202.1\|4429925_4431809_-\|tail	phage tail tape measure protein	NA	NA	NA	NA
WP_011535204.1\|4431939_4432236_-\|tail	phage tail assembly protein	B5TK69	Pseudomonas_phage	1.9e-34	79.4
WP_011535205.1\|4432232_4432580_-\|tail	phage tail tube protein	B5TK68	Pseudomonas_phage	4.0e-47	77.4
WP_011535206.1\|4432637_4434134_-\|tail	phage tail sheath subtilisin-like domain-containing protein	B5TK67	Pseudomonas_phage	1.3e-222	76.7
WP_011535207.1\|4434133_4434316_-	DUF2635 domain-containing protein	B5TK66	Pseudomonas_phage	3.6e-15	65.0
WP_011535208.1\|4434312_4434900_-	hypothetical protein	B5TK65	Pseudomonas_phage	1.3e-45	51.4
WP_011535209.1\|4434956_4435991_-	phage late control D family protein	A0A2H4JBF6	uncultured_Caudovirales_phage	8.8e-143	72.9
WP_044488368.1\|4436010_4436217_-\|tail	tail protein X	A0A2H4J9Z9	uncultured_Caudovirales_phage	6.7e-18	64.2
WP_011535211.1\|4436191_4437037_-\|tail	phage tail protein	A0A2H4J875	uncultured_Caudovirales_phage	5.8e-84	56.8
WP_011535212.1\|4437049_4439158_-	hypothetical protein	NA	NA	NA	NA
WP_011535213.1\|4439283_4439586_-\|tail	phage tail assembly protein	A0A2H4J873	uncultured_Caudovirales_phage	3.8e-22	59.6
WP_011535214.1\|4439598_4440108_-\|tail	phage major tail tube protein	A0A2H4JBU0	uncultured_Caudovirales_phage	1.2e-63	71.3
WP_011535215.1\|4440121_4441288_-\|tail	phage tail sheath family protein	A0A2H4J869	uncultured_Caudovirales_phage	9.9e-183	82.6
WP_158020303.1\|4441385_4441814_-	hypothetical protein	NA	NA	NA	NA
WP_158020267.1\|4441788_4442748_-	hypothetical protein	A0A2H4J931	uncultured_Caudovirales_phage	4.3e-35	57.1
WP_011535218.1\|4442744_4443176_-	phage protein	NA	NA	NA	NA
WP_011535219.1\|4443179_4445876_-\|tail	phage tail protein	M1TAS6	Escherichia_phage	7.6e-45	29.8
WP_011535220.1\|4445868_4446480_-\|tail	phage tail protein I	A0A2H4JDH5	uncultured_Caudovirales_phage	9.1e-63	60.0
WP_011535221.1\|4446481_4447363_-\|plate	baseplate J/gp47 family protein	A0A2H4JFK9	uncultured_Caudovirales_phage	1.1e-106	67.2
WP_011535222.1\|4447359_4447686_-	GPW/gp25 family protein	A0A2H4JA09	uncultured_Caudovirales_phage	8.1e-34	65.1
WP_011535223.1\|4447768_4448326_-\|plate	phage baseplate assembly protein V	A0A2H4JG06	uncultured_Caudovirales_phage	2.9e-55	60.1
WP_011535224.1\|4448322_4448820_-	hypothetical protein	A0A2H4J881	uncultured_Caudovirales_phage	1.7e-11	31.0
WP_011535225.1\|4448939_4449284_-	hypothetical protein	NA	NA	NA	NA
WP_011535226.1\|4449291_4450590_-	hypothetical protein	H9D1F9	Salinivibrio_phage	3.4e-06	48.6
WP_011535227.1\|4450797_4451178_-\|tail	tail fiber assembly protein	A0A2H4J9Z7	uncultured_Caudovirales_phage	9.5e-18	55.3
WP_011535228.1\|4451190_4452411_-	hypothetical protein	NA	NA	NA	NA
WP_011535229.1\|4452407_4452602_-	hypothetical protein	NA	NA	NA	NA
WP_011535230.1\|4452585_4452969_-	hypothetical protein	NA	NA	NA	NA
WP_011535231.1\|4452968_4456946_-	DUF1983 domain-containing protein	A0A1B0VMH5	Pseudomonas_phage	0.0e+00	56.1
WP_158020268.1\|4457004_4457217_-	hypothetical protein	NA	NA	NA	NA
WP_011535233.1\|4457206_4457539_-	hypothetical protein	I6PBW9	Pseudomonas_phage	2.4e-17	52.5
WP_011535234.1\|4457538_4458546_-	hypothetical protein	A0A0S2SY45	Pseudomonas_phage	4.9e-05	32.4
WP_011535235.1\|4458568_4459180_-\|tail	tail assembly protein	A0A1B0VMI5	Pseudomonas_phage	3.7e-64	64.5
WP_011535236.1\|4459246_4460011_-	C40 family peptidase	A0A2H4J1J7	uncultured_Caudovirales_phage	4.7e-109	68.8
WP_011535237.1\|4460014_4460764_-\|tail	phage minor tail protein L	A0A1B0VNE0	Pseudomonas_phage	1.6e-109	74.8
WP_011535238.1\|4460782_4461115_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	2.4e-33	60.0
WP_011535239.1\|4461130_4462396_-\|tail	phage tail tape measure protein	A0A1B0VMG8	Pseudomonas_phage	3.0e-36	33.7
WP_011535240.1\|4462462_4462717_-	hypothetical protein	A0A0U4J8S9	Pseudomonas_phage	4.2e-14	50.6
WP_011535241.1\|4462746_4463097_-\|tail	phage tail assembly chaperone family protein, TAC	NA	NA	NA	NA
WP_011535242.1\|4463111_4463603_-\|tail	phage major tail protein	H2BDC0	Pseudomonas_virus	2.1e-46	58.1
WP_011535243.1\|4463688_4463871_-	hypothetical protein	NA	NA	NA	NA
WP_011535244.1\|4463885_4464239_-	pyocin	B5TK61	Pseudomonas_phage	7.9e-43	83.5
WP_011535246.1\|4464706_4465453_-	helix-turn-helix transcriptional regulator	B5TK58	Pseudomonas_phage	9.3e-118	84.3
WP_011535247.1\|4465628_4468202_+	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	2.6e-26	23.2
WP_011535248.1\|4468341_4468665_+	ferredoxin family protein	NA	NA	NA	NA
WP_011535249.1\|4469137_4470145_-	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	3.9e-34	35.8
WP_044488887.1\|4470250_4471105_-	peptidoglycan DD-metalloendopeptidase family protein	I3PV79	Clostridium_phage	1.9e-13	36.2
WP_162042960.1\|4471285_4471924_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	3.9e-40	50.6
WP_011535252.1\|4471962_4472712_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.4e-65	51.4
WP_011535253.1\|4472699_4473758_-\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_011535254.1\|4473754_4474228_-	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_193383927.1\|4474382_4475237_-	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_011535256.1\|4475241_4476354_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	1.4e-32	29.3
WP_011535257.1\|4476462_4477365_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011535258.1\|4477465_4478173_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_011535259.1\|4478169_4478451_-	cell division protein FtsB	NA	NA	NA	NA
WP_011535260.1\|4478609_4479899_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	5.1e-140	59.9
WP_011535261.1\|4480051_4480897_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	5.9e-52	42.4
WP_011535262.1\|4480900_4482529_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.5e-157	52.9
WP_011535263.1\|4482798_4484094_-\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA

DBSCAN-SWA_4

5417436 : 5427034

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044488524.1\|5417436_5419329_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.2e-28	32.9
WP_011536095.1\|5419452_5420049_-	DUF924 domain-containing protein	A0A1V0SIY0	Klosneuvirus	1.1e-15	32.1
WP_011536096.1\|5420052_5421063_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	7.8e-51	35.5
WP_011536097.1\|5421217_5423683_-	glycogen/starch/alpha-glucan phosphorylase	A0A140XAG6	Dickeya_phage	4.4e-07	42.9
WP_011536098.1\|5423880_5424285_+	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_009681539.1\|5424298_5424457_-	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_011536099.1\|5424622_5425900_-	aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	B5LJF5	Mycobacterium_phage	2.5e-14	32.5
WP_011536100.1\|5426110_5427034_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	3.0e-09	28.9

DBSCAN-SWA_5

5477627 : 5519184

Tupanvirus(25.0%)

transposase,holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011536140.1\|5477627_5478128_-\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_011536141.1\|5478310_5479198_+	acyltransferase	NA	NA	NA	NA
WP_011536142.1\|5479296_5479866_-	DUF2780 domain-containing protein	NA	NA	NA	NA
WP_011536143.1\|5480022_5481222_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	1.3e-12	28.5
WP_011536144.1\|5481475_5482333_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_011536145.1\|5482345_5482978_-	sarcosine oxidase subunit gamma family protein	NA	NA	NA	NA
WP_011536146.1\|5483149_5486167_-	sarcosine oxidase subunit alpha	NA	NA	NA	NA
WP_011536147.1\|5486163_5486499_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_011536148.1\|5486515_5487766_-	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_011536149.1\|5487781_5489035_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	7.8e-101	53.0
WP_011536150.1\|5489352_5490393_+	low specificity L-threonine aldolase	NA	NA	NA	NA
WP_011536151.1\|5490451_5492389_-	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_011536152.1\|5492573_5492876_-	cell division protein ZapA	NA	NA	NA	NA
WP_011536153.1\|5492872_5493103_-	hypothetical protein	NA	NA	NA	NA
WP_011536154.1\|5493380_5495006_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.3e-75	45.8
WP_011536155.1\|5495065_5496166_-	glycine-betaine demethylase subunit GbcB	NA	NA	NA	NA
WP_011536156.1\|5496464_5497757_+	glycine-betaine demethylase subunit GbcA	NA	NA	NA	NA
WP_011536157.1\|5497952_5498408_+\|transposase	transposase	NA	NA	NA	NA
WP_011536158.1\|5498542_5498875_-	hypothetical protein	NA	NA	NA	NA
WP_011536159.1\|5498980_5499751_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_011536160.1\|5499762_5500995_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_011536161.1\|5500994_5502947_-	dimethylglycine demethylation protein DgcB	NA	NA	NA	NA
WP_011536162.1\|5503124_5505185_-	dimethylglycine demethylation protein DgcA	NA	NA	NA	NA
WP_011536163.1\|5505200_5505731_-	hypothetical protein	NA	NA	NA	NA
WP_011536164.1\|5505808_5506786_-	membrane dipeptidase	NA	NA	NA	NA
WP_011536165.1\|5507072_5507474_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_011536166.1\|5507588_5508533_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_011536167.1\|5508678_5509623_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011536168.1\|5509734_5510619_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_011536169.1\|5510743_5511709_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_011536170.1\|5511719_5512193_+	thioesterase family protein	NA	NA	NA	NA
WP_044488534.1\|5512478_5512736_+	hypothetical protein	NA	NA	NA	NA
WP_011536172.1\|5512815_5513922_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_044488535.1\|5514311_5515688_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_011536174.1\|5516131_5517079_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_193383931.1\|5517160_5518009_+\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_011536176.1\|5518005_5519184_+\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.5e-24	36.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage