CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_000907	Haemophilus influenzae Rd KW20, complete sequence	2 crisprs	DEDDh,DinG,cas3	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_000907_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_000907_1

1633449-1633543

Orphan

Consensus_repeat	Method
TTGGTGGGCTGAAGCCCACCCTACAACTACTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_000907_1

>merge|NC_000907|1|1633449-1633543|CRISPRCasFinder
TTGGTGGGCTGAAGCCCACCCTACAACTACTAAAGCCCACCAAAATATCTCTCGATTGTTTTTTGGTGGGCTAAAGCCCACCCTACAACTACTAA

>NC_000907|1|1|1633449-1633543|CRISPRCasFinder
TTGGTGGGCTGAAGCCCACCCTACAACTACTAA	AGCCCACCAAAATATCTCTCGATTGTTTT
TTGGTGGGCTAAAGCCCACCCTACAACTACTAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_000907.1\|WP_005693583.1\|1626904_1627852_-\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|235890
NC_000907.1\|WP_005693601.1\|1646701_1647673_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NC_000907.1\|WP_005654778.1\|1625723_1626905_-\|lipoprotein-releasing-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|274034
NC_000907.1\|WP_005693598.1\|1643225_1644308_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143500
NC_000907.1\|WP_005693586.1\|1627911_1628766_-\|3-deoxy-8-phosphooctulonate-synthase	unknown	unknown	gnl\|CDD\|235363
NC_000907.1\|WP_005688500.1\|1632146_1632359_-\|hypothetical-protein	unknown	unknown	unknown
NC_000907.1\|WP_032828363.1\|1641809_1643216_+\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|136106
NC_000907.1\|WP_032803489.1\|1630954_1632037_-\|peptide-chain-release-factor-1	unknown	unknown	gnl\|CDD\|234801
NC_000907.1\|WP_005688499.1\|1630461_1630902_-\|RDD-family-protein	unknown	unknown	gnl\|CDD\|224628
NC_000907.1\|WP_100066292.1\|1638048_1638282_-\|DUF935-family-protein	unknown	unknown	gnl\|CDD\|226818
NC_000907.1\|WP_005693587.1\|1629583_1630462_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl\|CDD\|273125
NC_000907.1\|WP_005688501.1\|1632557_1633094_-\|elongation-factor-P-hydroxylase	unknown	unknown	gnl\|CDD\|225643
NC_000907.1\|WP_005693592.1\|1636790_1637207_-\|phage-virion-morphogenesis-protein	unknown	unknown	gnl\|CDD\|227338
NC_000907.1\|WP_010869250.1\|1647855_1648323_-\|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl\|CDD\|225675
NC_000907.1\|WP_005688502.1\|1633126_1633279_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235035
NC_000907.1\|WP_005647229.1\|1651322_1651814_-\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183365
NC_000907.1\|WP_010869247.1\|1640231_1641668_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NC_000907.1\|WP_005654786.1\|1628780_1629584_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|225464
NC_000907.1\|WP_010869249.1\|1644404_1646054_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234679
NC_000907.1\|WP_005693602.1\|1649296_1651030_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|273085

Protein	Function_ID	Function_description	E-value
NC_000907.1\|WP_005693583.1\|1626904_1627852_-\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|235890	PRK06932, PRK06932, 2-hydroxyacid dehydrogenase.	0
NC_000907.1\|WP_005693601.1\|1646701_1647673_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.64569e-36
NC_000907.1\|WP_005654778.1\|1625723_1626905_-\|lipoprotein-releasing-ABC-transporter-permease-subunit	gnl\|CDD\|274034	TIGR02212, releasing_system_transmembrane_protein_lolC., lipoprotein releasing system, transmembrane protein, LolC/E family. This model describes the LolC protein, and its paralog LolE found in some species. These proteins are homologous to permease proteins of ABC transporters. In some species, two paralogs occur, designated LolC and LolE. In others, a single form is found and tends to be designated LolC. [Protein fate, Protein and peptide secretion and trafficking].	8.7758e-168
NC_000907.1\|WP_005693598.1\|1643225_1644308_+\|alanine-racemase	gnl\|CDD\|143500	cd06827, PLPDE_III_AR_proteobact, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases. This subfamily is composed mainly of proteobacterial alanine racemases (EC 5.1.1.1), fold type III PLP-dependent enzymes that catalyze the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. hese proteins are similar to other bacterial ARs and are fold type III PLP-dependent enzymes containing contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Homodimer formation and the presence of the PLP cofactor are required for catalytic activity.	0
NC_000907.1\|WP_100066292.1\|1638048_1638282_-\|DUF935-family-protein	gnl\|CDD\|226818	COG4383, COG4383, Mu-like prophage protein gp29 [Function unknown].	1.52778e-41
NC_000907.1\|WP_032828363.1\|1641809_1643216_+\|replicative-DNA-helicase	gnl\|CDD\|136106	PRK06904, PRK06904, replicative DNA helicase; Validated.	0
NC_000907.1\|WP_032803489.1\|1630954_1632037_-\|peptide-chain-release-factor-1	gnl\|CDD\|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NC_000907.1\|WP_005688499.1\|1630461_1630902_-\|RDD-family-protein	gnl\|CDD\|224628	COG1714, COG1714, Predicted membrane protein/domain [Function unknown].	2.41297e-16
NC_000907.1\|WP_005693586.1\|1627911_1628766_-\|3-deoxy-8-phosphooctulonate-synthase	gnl\|CDD\|235363	PRK05198, PRK05198, 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional.	0
NC_000907.1\|WP_005693587.1\|1629583_1630462_-\|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl\|CDD\|273125	TIGR00536, Release_factor_glutamine_methyltransferase, HemK family putative methylases. The gene hemK from E. coli was found to contribute to heme biosynthesis and originally suggested to be protoporphyrinogen oxidase (Medline 95189105). Functional analysis of the nearest homolog in Saccharomyces cerevisiae, YNL063w, finds it is not protoporphyrinogen oxidase and sequence analysis suggests that HemK homologs have S-adenosyl-methionine-dependent methyltransferase activity (Medline 99237242). Homologs are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both E. coli and H. influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain. [Protein fate, Protein modification and repair].	4.77504e-125
NC_000907.1\|WP_005688501.1\|1632557_1633094_-\|elongation-factor-P-hydroxylase	gnl\|CDD\|225643	COG3101, COG3101, Uncharacterized protein conserved in bacteria [Function unknown].	1.00546e-114
NC_000907.1\|WP_005693592.1\|1636790_1637207_-\|phage-virion-morphogenesis-protein	gnl\|CDD\|227338	COG5005, COG5005, Mu-like prophage protein gpG [General function prediction only].	6.07005e-73
NC_000907.1\|WP_010869250.1\|1647855_1648323_-\|glycine-zipper-2TM-domain-containing-protein	gnl\|CDD\|225675	COG3133, SlyB, Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane].	4.24972e-60
NC_000907.1\|WP_005688502.1\|1633126_1633279_-\|hypothetical-protein	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	7.88649e-10
NC_000907.1\|WP_005647229.1\|1651322_1651814_-\|acetolactate-synthase-small-subunit	gnl\|CDD\|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	2.20598e-89
NC_000907.1\|WP_010869247.1\|1640231_1641668_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NC_000907.1\|WP_005654786.1\|1628780_1629584_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|225464	COG2912, COG2912, Uncharacterized conserved protein [Function unknown].	1.21762e-110
NC_000907.1\|WP_010869249.1\|1644404_1646054_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NC_000907.1\|WP_005693602.1\|1649296_1651030_+\|arginine--tRNA-ligase	gnl\|CDD\|273085	TIGR00456, Arginine--tRNA_ligase, arginyl-tRNA synthetase. This model recognizes arginyl-tRNA synthetase in every completed genome to date. An interesting feature of the alignment of all arginyl-tRNA synthetases is a fairly deep split between two families. One family includes archaeal, eukaryotic and organellar, spirochete, E. coli, and Synechocystis sp. The second, sharing a deletion of about 25 residues in the central region relative to the first, includes Bacillus subtilis, Aquifex aeolicus, the Mycoplasmas and Mycobacteria, and the Gram-negative bacterium Helicobacter pylori. [Protein synthesis, tRNA aminoacylation].	0

>NC_000907.1|WP_005688502.1|1633126_1633279_-|hypothetical-protein
MEKTGLPLSLESFQQLLPQIFMRAKGRSIRLIGLHVNLPEENKQEQMSLW
>NC_000907.1|WP_005688501.1|1632557_1633094_-|elongation-factor-P-hydroxylase
MEHKLEDIIAIFNQCFEEEYNTRLVKGGDEPIYLPANDEVPYNAIYFARGFYSSALHEIAHWLVAGKERRKLEDFGYWYEPDGRSEERQRDFEKVEVKPQALEWILATAAGFRYFASADNLNGNPGDTQPFKQAVYEQVKIYAEKGLPKRAETLRKALVAFYSTEDDINLAKFDVTCI
>NC_000907.1|WP_005688500.1|1632146_1632359_-|hypothetical-protein
MPKQPDLQEKIEAIKEELVLSKDPKVLIKLGELEKDKSKAKKYFGDACDLRSQEGCDKYRELNQKQDTNK
>NC_000907.1|WP_032803489.1|1630954_1632037_-|peptide-chain-release-factor-1
MKDSIIAKLESLKERYEELEALLGDVSVISDQDKFRAYSKEYSQLEEVVKCFNRWTQLNQNIEEAEILLDDPEMKEMAQMEIEESKAEIEEVEQQLQILLLPKDPNDEYNCYLEIRAGTGGDEAGIFAGDLFRMYSRYAESKRWRVEMLSANESEQGGYKEVIVKVTGEGVYGQLKFESGGHRVQRVPKTESQGRIHTSACTVAVMPELPESEMPEINPADLRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVECQDERSQHKNKAKAMSVLASRIVQAEQERQAAEQTDMRRNLLGSGDRSDKIRTYNYPQGRVTDHRINLTIYRLDEVMNGKIDELIQPIITEYQADQLAALSEQN
>NC_000907.1|WP_005688499.1|1630461_1630902_-|RDD-family-protein
MIIENQKDAEFSSAFKPSQLAQASRFKRWLASMINGLVLWVMAGLGFALGDFAGVVGMIVYAGFQLYFMKTYGQTMAKRWLGLRVFNYHTNQPVEFGKYIGREIIDILLAWTSFLLIISGIVALVRDDRRSLTDLVAGTIVLKDEK
>NC_000907.1|WP_005693587.1|1629583_1630462_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MNYKEWLAQAIADLAKKNPTENSKIDALVLLQHATGKSRTQILAFDDTEIDEKVRLKLTALLDRRLKGEPIAYILGEKEFWSLPLNVSKGTLIPRPDTEILVEKALQIALEKLEENPPHFRILDLGTGTGAIALALASELAPICQKRHIPLEIIGVDLMSDVVALAQSNAERNQLNVEFLQSRWFDNITGKFDLIVSNPPYIDAQDEHLHQGDVRFEPLSALVANDEGYADLRHIIELASSYLNSNGVLLLEHGWQQGEKVRSIFQENHWEMVETVRDYSDNERVTLGFWKK
>NC_000907.1|WP_005654786.1|1628780_1629584_-|tetratricopeptide-repeat-protein
MKYYRRALYDKFVHFYLVISDDGSSEAQLRGKMGGLVRKARKKISPDWPKEEQIHQLLQLFYGDWGFHCDPEDYFYARNLYLPYVFEHRQGMPVTLGAMVFYLAEALDLPIYPVNFPTQLILRAEVRDEVAFIDPWDGTYISQEKLQQLYEGAFGFGAKIQPEELDRADLSLLYSRFEQLAKNALIREEHNDMAYHYIKNLMITDAENPYHIRDRGLVLAQMGAYPSALKDLEFFVEHCPKDPTAAFIRTQLLELKGEINKDTFPLH
>NC_000907.1|WP_005693586.1|1627911_1628766_-|3-deoxy-8-phosphooctulonate-synthase
MQNKIVKIGNIDVANDKPFVLFGGMNVLESRDMAMQVCEAYVKVTEKLGVPYVFKASFDKANRSSIHSYRGPGMEEGLKIFQELKDTFGVKIITDVHEIYQCQPVADVVDIIQLPAFLARQTDLVEAMAKTGAVINVKKPQFLSPSQMGNIVEKIEECGNDKIILCDRGTNFGYDNLIVDMLGFSVMKKASKGSPVIFDVTHSLQCRDPFGAASSGRRAQVTELARSGLAVGIAGLFLEAHPNPNQAKCDGPSALPLSALEGFVSQMKAIDDLVKSFPELDTSI
>NC_000907.1|WP_005693583.1|1626904_1627852_-|2-hydroxyacid-dehydrogenase
MKIVFLDSTAIPKHISIPRPSFEHTWTEYEHTSAEQTIERVKDADIVITSKVIFDRETLQQLPKLKLIAITATGTNNVDLVAAEEMGIAVRNVTGYSSTTVPEHVIGLIFSLKHSLAGWLRDQTEAKWAESKQFCYFDYPITDVRGSTLGVFGKGCLGTEVGRLANAVGMKVLYAEHKDATVCREGYTPFDEVLKQADIVTLHCPLTETTKDLINAETLSKMKKGAFLINTGRGPLIDELALVDALKTGHLGGAALDVMVKEPPEKDNPLILAAKTMPNLIITPHIAWASDSAVTTLVGKVMQNIEEFVQQLHQK
>NC_000907.1|WP_005654778.1|1625723_1626905_-|lipoprotein-releasing-ABC-transporter-permease-subunit
MNFPISLYIALRYWRAKSADRFGRLVTNLASLGIVLGVMALIIVLSVMNGLEGYQKQQVLSSIPHAIVSEEQPISTEKTLENLPHFVQKAVPINTTNVIYQTAKGVSAGQIIGIQSFSDDPLVESFDQTKFNEILPRGEFKLVIGDQLAQKLGVNIGDKIRLMITENSQYTPFGRVPMQRLFTVSDIYYGYGEASGYEAFANITDIGRLMRIQPQQAQGYRLFLNDPFQITELPQHFPTQKITDWRVQKGEFFQAVRMEKNMMGLLISLIIVVAISNIVTSLSLMVVDKQGEIAILQTQGLTKSQVRSVFIYQGLLVGFVGTLLGAILGVLATLNLTDIVSAVNPQGVFLPTELSFVQMIFVIGFSLLLSLLSTLYPAYRAAKVEPAAALRYE
>NC_000907.1|WP_005693592.1|1636790_1637207_-|phage-virion-morphogenesis-protein
MIEIEINNAQEITSALERLAQATAHRAPLMRSIAGTMESAVAQNFEVGGRPAWKKLKIRQGTPLVDTENLMASITSEYNNNEAIVGTNEPYAAIHQFGGKAGRGRKVAIPARPFLILTPQDEADILEDIQDYFQLLIK
>NC_000907.1|WP_100066292.1|1638048_1638282_-|DUF935-family-protein
MRHLAQIITQQIILPYLQINVDPNIAPHRIPYFEFDTKEYEDLSVFADAIPKLTGIGVQISESWVWDKLGIPEPQEG
>NC_000907.1|WP_010869247.1|1640231_1641668_+|pyruvate-kinase
MSRRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVSTFKDGKIFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNKGINKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANDEAMDDIILASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFETIEESVAMSAMYAANHMKGVAAIVTLSSTGRTPLLMSRISSGLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAAPQSLKEKGYLSTGDLVLVTQGGQGATQTNVCRTLIVE
>NC_000907.1|WP_032828363.1|1641809_1643216_+|replicative-DNA-helicase
MASQPQIKSSDKKTAQVSIPPHSTEAEQAVLGGIMLSNQHWDGIAERVIADDFYTFQHRLIFTEMEHLMRNQSPIDLITLDQALRSRGVSDEVGGFAYLAELSNNTPNAINILAYADIVREKAILRELISVGNRIAENSYSPKGQDIKLILDEAEREVFAIAEKRTTSSEGPQNVINVLESTIEKIDILSKLENHSGVTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSLEMPAEQIMMRMIASLARVDQTKIRTGQNLDEIEWNKIASVVGMFKQKNNLFIDDSSGLTPTDVRSRARRVYRENGGLSMIMVDYLQLMRAPAFSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRTLEQRGDKRPVNSDLRESGSIEQDADLIMFIYRDEVYNDNSEDKGVAEIIIGKQRNGPIGRVRLKFNGQFSRFDNLAEQREYRDDY
>NC_000907.1|WP_005693598.1|1643225_1644308_+|alanine-racemase
MNVKPATAKISSHALKQNLEIIKQKAPNSKIIAVVKANAYGHGVVFVASTLEQNVDCFGVARLEEALALRSNGITKPILLLEGFFNEQDLPILAVNNIETVVHNHEQLDALKRANLPSPIKVWLKIDTGMHRLGVALDEVDYFYQELKKLPQIQPHLGFVSHFSRADELESDYTQLQINRFLSVTKDKQGERTIAASGGILFWPKSHLECIRPGIIMYGISPTDTIGKEFGLTPVMNLTSSLIAVRHHKQGDPVGYGGIWTSPRDTKIGVVAMGYGDGYPRDVPEGTPVYLNGRLVPIVGRVSMDMLTVDLGADSQDLVGDEVILWGKELPIETVAKFTGILSYELITKLTPRVITEYVD
>NC_000907.1|WP_010869249.1|1644404_1646054_+|glucose-6-phosphate-isomerase
MKNINPTHTHAWKSLEAHKAELSNITIQDLFKQEKNRFDDYSLTFNNQILIDFSKNNINQTTLSHLRQLAQECALDSAKEAMFTGEKINRTENRAVLHTALRNRTNTPVLVDGKDVMPEVNAVLAKMKDFCQRIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAETLKKVNPETTLFLVASKTFTTQETMTNAQSARDWLLKAAKDESAVAKHFAALSTNAKDVEKFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSIGFENFEALLNGAHEMDKHFLSTPIEQNIPTTLALVGLWNTNFLGAQTEAILPYDQYLHRFAAYFQQGNMESNGKYVDRDGNVIKNYQTGPIIWGEPGTNGQHAFYQLIHQGTTLIPCDFIAPAQRHNPLADHHNKLLSNFFAQTEALAFGKTKEEVEAEFVKAGKSLDDVKNIVPFKVFTGNKPTNSILVQKITPFTLGALIAMYEHKIFVQGVIFNIFSFDQWGVELGKQLANRILPELTDSEKVASHDSSTNGLINQFKAWR
>NC_000907.1|WP_005693601.1|1646701_1647673_+|glycosyltransferase-family-2-protein
MENCPLVSVIVCAYNAEQYIDESISSIINQTYENLEIIVINDGSTDLTLSHLEEISKLDKRIKIISNKYNLGFINSLNIGLGCFSGKYFARMDADDIAKPSWIEKIVTYLEKNDHITAMGSYLEIIVEKECGIIGSQYKTGDIWKNPLLHNDICEAMLFYNPIHNNTMIMRANVYREHKLIFNKDYPYAEDYKFWSEVSRLGCLANYPEALVKYRLHGNQTSSVYNHEQNETAKKIKRENITYYLNKIGIDIKVINSVSLLEIYHVDKSNKVLKSILYEMYMSLDKYTITSLLHFIKYHLELFDLKQNLKIIKKFIRKINVIF
>NC_000907.1|WP_010869250.1|1647855_1648323_-|glycine-zipper-2TM-domain-containing-protein
MKKTNMALALLVAFSVTGCANTDIFSGDVYSASQAKEARSITYGTIVSVRPVKIQADNQGVVGTLGGGALGGIAGSTIGGGRGQAIAAVVGAIGGAIAGSKIEEKMSQVNGAELVIKKDDGQEIVVVQKADSSFCSLVAEFVFVGGGSSLNVSVL
>NC_000907.1|WP_005693602.1|1649296_1651030_+|arginine--tRNA-ligase
MNIQSILSDKIKQAMILAGADQSCDALIRQSGKPQFGDYQANGIMAAAKKLGLNPREFAQKVLDNLQLSDIAEKLEIAGPGFINIFLNPTWLTTEISAALSHKNLGIQATNKQTVVIDYSSPNVAKEMHVGHLRSTIIGDAVARTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNEHASEMELQDLEAFYREAKKHYDEDEVFAEKARNYVVKLQSGDEYCRTMWKRLVDITMQQNQHNYARLNVTLTEKDVMGESLYNPMLPSIVKDLKKQGLAVENDGALVVYLDEFKNKDGDPMGVIVQKKDGGFLYTTTDIAAAKYRYETLKANRALVFSDTRQSQHMQQAWLITRKAGYVPDSFSLEHKNFGMMLGKDGKPFKTRTGGTVKLADLLDEAIERATVLINEKNTNLSNDEKEAVIEAVGIGAVKYADLSKNRTTDYVFDWDNMLSFEGNTAPYMQYAYTRIRSIFNKTDINSTALLAAPLTIKDDKERTLAIKLLQFEEAVQTVGKEGTPHVLCAYLYELAGIFSSFYEHCPILNAEDESIKLSRLKLALLTEKTLKQGLTLLGIKTVEKM
>NC_000907.1|WP_005647229.1|1651322_1651814_-|acetolactate-synthase-small-subunit
MRRILSVLLENESGALSRVVGLFSQRAFNIESLTVAPTDDPTLSRMTIEAVGDAQALEQIEKQLHKLVDVFKVVNLSEQEHIEREIVLAKVRAVGSSRDEIKRLADIFRGQIVDVTPKSYTIQLSGTNDKVDAFISALKEETTLLEIVRSGLISVSRGEKNIL

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Crispr_ID: NC_000907_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_000907_2

1759111-1759203

Orphan

Consensus_repeat	Method
AAATCTTGCCTTCCCCTGCTTGCGGGGGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_000907_2

>merge|NC_000907|2|1759111-1759203|CRISPRCasFinder
AAATCTTGCCTTCCCCTGCTTGCGGGGGAAGGTATCACAAAGTGACAAAAAGAGGCTCAAAGAAAATCTTGCCTTCCCCTGCTTGCGGGGGAA

>NC_000907|2|2|1759111-1759203|CRISPRCasFinder
AAATCTTGCCTTCCCCTGCTTGCGGGGGAA	GGTATCACAAAGTGACAAAAAGAGGCTCAAAGA
AAATCTTGCCTTCCCCTGCTTGCGGGGGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_000907.1\|WP_005654374.1\|1762419_1763148_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NC_000907.1\|WP_005654382.1\|1759287_1759923_+\|endonuclease-III	unknown	unknown	gnl\|CDD\|182661
NC_000907.1\|WP_005694179.1\|1759980_1761354_+\|sodium-dependent-transporter	unknown	unknown	gnl\|CDD\|271367
NC_000907.1\|WP_005658208.1\|1758395_1759103_+\|electron-transport-complex-subunit-E	unknown	unknown	gnl\|CDD\|237091
NC_000907.1\|WP_010869271.1\|1754230_1756690_+\|electron-transport-complex-subunit-RsxC	unknown	unknown	gnl\|CDD\|235334
NC_000907.1\|WP_005665007.1\|1747912_1748455_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|224692
NC_000907.1\|WP_005650033.1\|1753648_1754230_+\|electron-transport-complex-subunit-RsxB	unknown	unknown	gnl\|CDD\|235347
NC_000907.1\|WP_005694402.1\|1751639_1752701_+\|protease-SohB	unknown	unknown	gnl\|CDD\|236978
NC_000907.1\|WP_005654151.1\|1750776_1751442_-\|DUF2057-domain-containing-protein	unknown	unknown	gnl\|CDD\|234990
NC_000907.1\|WP_005694182.1\|1763282_1764047_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|182641
NC_000907.1\|WP_005694186.1\|1766761_1767535_-\|glycosyltransferase-family-25-protein	unknown	unknown	gnl\|CDD\|225843
NC_000907.1\|WP_164927871.1\|1765060_1765864_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133038
NC_000907.1\|WP_005694178.1\|1757770_1758394_+\|electron-transport-complex-subunit-RsxG	unknown	unknown	gnl\|CDD\|179350
NC_000907.1\|WP_005694183.1\|1764184_1764952_+\|TOBE-domain-containing-protein	unknown	unknown	gnl\|CDD\|182640
NC_000907.1\|WP_005694187.1\|1767546_1768608_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340847
NC_000907.1\|WP_005694180.1\|1761377_1762433_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NC_000907.1\|WP_005694177.1\|1756694_1757771_+\|electron-transport-complex-subunit-RsxD	unknown	unknown	gnl\|CDD\|234844
NC_000907.1\|WP_005665016.1\|1748552_1750709_-\|TIGR01666-family-membrane-protein	unknown	unknown	gnl\|CDD\|130727
NC_000907.1\|WP_005694185.1\|1765865_1766750_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NC_000907.1\|WP_005694403.1\|1752982_1753561_+\|electron-transport-complex-subunit-RsxA	unknown	unknown	gnl\|CDD\|235352

Protein	Function_ID	Function_description	E-value
NC_000907.1\|WP_005654374.1\|1762419_1763148_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.21503e-141
NC_000907.1\|WP_005654382.1\|1759287_1759923_+\|endonuclease-III	gnl\|CDD\|182661	PRK10702, PRK10702, endonuclease III; Provisional.	1.33178e-139
NC_000907.1\|WP_005694179.1\|1759980_1761354_+\|sodium-dependent-transporter	gnl\|CDD\|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	2.74469e-164
NC_000907.1\|WP_005658208.1\|1758395_1759103_+\|electron-transport-complex-subunit-E	gnl\|CDD\|237091	PRK12405, PRK12405, electron transport complex RsxE subunit; Provisional.	2.49211e-131
NC_000907.1\|WP_010869271.1\|1754230_1756690_+\|electron-transport-complex-subunit-RsxC	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0
NC_000907.1\|WP_005665007.1\|1747912_1748455_+\|HAD-family-hydrolase	gnl\|CDD\|224692	COG1778, COG1778, Low specificity phosphatase (HAD superfamily) [General function prediction only].	5.81759e-89
NC_000907.1\|WP_005650033.1\|1753648_1754230_+\|electron-transport-complex-subunit-RsxB	gnl\|CDD\|235347	PRK05113, PRK05113, electron transport complex protein RnfB; Provisional.	1.12731e-113
NC_000907.1\|WP_005694402.1\|1751639_1752701_+\|protease-SohB	gnl\|CDD\|236978	PRK11778, PRK11778, putative inner membrane peptidase; Provisional.	0
NC_000907.1\|WP_005654151.1\|1750776_1751442_-\|DUF2057-domain-containing-protein	gnl\|CDD\|234990	PRK01904, PRK01904, DUF2057 domain-containing protein.	1.44456e-117
NC_000907.1\|WP_005694182.1\|1763282_1764047_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	9.20857e-99
NC_000907.1\|WP_005694186.1\|1766761_1767535_-\|glycosyltransferase-family-25-protein	gnl\|CDD\|225843	COG3306, COG3306, Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane].	2.05975e-56
NC_000907.1\|WP_164927871.1\|1765060_1765864_-\|glycosyltransferase	gnl\|CDD\|133038	cd04195, GT2_AmsE_like, GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis. AmsE is a glycosyltransferase involved in exopolysaccharide amylovora biosynthesis in Erwinia amylovora. Amylovara is one of the three exopolysaccharide produced by E. amylovora. Amylovara-deficient mutants are non-pathogenic. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.	4.31883e-119
NC_000907.1\|WP_005694178.1\|1757770_1758394_+\|electron-transport-complex-subunit-RsxG	gnl\|CDD\|179350	PRK01908, PRK01908, electron transport complex protein RnfG; Validated.	3.86369e-127
NC_000907.1\|WP_005694183.1\|1764184_1764952_+\|TOBE-domain-containing-protein	gnl\|CDD\|182640	PRK10676, PRK10676, DNA-binding transcriptional regulator ModE; Provisional.	2.82038e-82
NC_000907.1\|WP_005694187.1\|1767546_1768608_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340847	cd03820, GT4_AmsD-like, amylovoran biosynthesis glycosyltransferase AmsD and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.	1.87572e-135
NC_000907.1\|WP_005694180.1\|1761377_1762433_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NC_000907.1\|WP_005694177.1\|1756694_1757771_+\|electron-transport-complex-subunit-RsxD	gnl\|CDD\|234844	PRK00816, rnfD, electron transport complex protein RnfD; Reviewed.	0
NC_000907.1\|WP_005665016.1\|1748552_1750709_-\|TIGR01666-family-membrane-protein	gnl\|CDD\|130727	TIGR01666, Uncharacterized_protein_HI_1680, TIGR01666 family membrane protein. This model represents a clade of sequences from gamma and beta proteobacteria. These proteins are >700 amino acids long and many have been annotated as putative membrane proteins. The gene from Salmonella has been annotated as a putative efflux transporter. The gene from E. coli has the name yccS. [Cell envelope, Other].	0
NC_000907.1\|WP_005694185.1\|1765865_1766750_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.17088e-32
NC_000907.1\|WP_005694403.1\|1752982_1753561_+\|electron-transport-complex-subunit-RsxA	gnl\|CDD\|235352	PRK05151, PRK05151, electron transport complex protein RsxA; Provisional.	3.61742e-111

>NC_000907.1|WP_005658208.1|1758395_1759103_+|electron-transport-complex-subunit-E
MTDLTEKNTALEEEKIESAVENQQKSIWKEIFAQGIWKNNPAVVQLLGLCPLLAVSSTATNALGLGLATMLVLTCTNTVISLFRQYIPKEIRIPIYVMIIATTVTAVQLLMNAYTYTLYQSLGIFIPLIVTNCIIIGRAEAFASKNSLLHSIWDGFSMGLGMALSLTILGALREIIGQGTIFEGIENLFGEQAKFLTHHIYHTDSSFLLFILPPGAFIGLGLLLAIKNRIDNIKK
>NC_000907.1|WP_005694178.1|1757770_1758394_+|electron-transport-complex-subunit-RsxG
MGTVKITSRYGILLGFIALLCTIISAGIFFLTKDKIDAVIAAQQRELLLQVIPQDYFNNNLLESAVIPQDKNFVGIQKIYFAKKDGNVSAYAYETTAPDGYSGDIRLLVGLDPKGEVLGVRVIEHHETPGLGDKIERRISNWILGFTNQSINEHNLSEWAVKKDGGKFDQFSGATITPRAVVNQTKRSALIMLNNQALLQQLSTQVK
>NC_000907.1|WP_005694177.1|1756694_1757771_+|electron-transport-complex-subunit-RsxD
MFKMVSSPHTHSGKLTAHIMLWAILAMMPAFFTQIYYFGFGVVLQSALAIGTAIIAEFIAIKLRGKKPLNYLSDFSVALTALILAMAIPPYAPYWIIIIGTLCAVLLGKQVYGGLGQNPFNPAMIGYVILLISFPLQMTTWMPPINLLQEPPTFSDAFSLIFSGLTTDGFTLSQLTHNIDGITQATPLDSAKIFYKSHTQLNDFYELIKLPIFMGNGTDFAQGWWQINVAFLAGGIFLILKRVIHWQIPVAMLVTFFCLATATAFTGFTHLSAISQLVSGAMMFGAFFIATDPVTASITPRGKIIFGALVGLFVYLIRYHGNYPDGVAFAILLSNICVPLIDHYTRPRVSGYPTKGRK
>NC_000907.1|WP_010869271.1|1754230_1756690_+|electron-transport-complex-subunit-RsxC
MADVLSRFNSGKLWDFKGGIHPPEMKSQSNSQPLRHLPLGTDFYIPLKQHLGTTGNLLIKEGDYVLKGQALTKGDGLRMLPVHAPTSGTIKSIKPYVATHPSGLDEPTIHLQADGLDQWIERNPIDDFSTLSSEQLIHKIYQAGIAGLGGAVFPTAAKIQSAEQKVKLLIINGAECEPYITCDDRLMRERADEIIKGIRILRYILHPEKVVIAIEDNKPEAISAIRNALQGANDISIRVIPTKYPSGATKQLIYLLTGIEVPSGERSSSIGVLMQNVGTMFAIKRAIINDEPLIERVVTLTGNKIAEKGNYWVRLGTPISQILSDAGYQFDKHFPIFAGGPMMGLELPNLNAPVTKLVNCLLAPDYLEYAEPEAEQACIRCSSCSDACPVNLMPQQLYWFARSEDHKKSEEYALKDCIECGICAYVCPSHIPLIQYFRQEKAKIWQIKEKQKKSDEAKIRFEAKQARMEREEQERKARSQRAAQARREELAQTKGEDPVKAALERLKAKKANETESTQIKTLTSEKGEVLPDNTDLMAQRKARRLARQQAASQVENQEQQTQPTNAKKAAVAAALARAKAKKLAQANSTSEAISNSQTAENQVEKTKSAVEKTQENSTALDPKKAAVAAAIARAKAKKLAQTNSTSEAISNSQTAENEVEKTKSAVEKTEENSTALDAKKAAIAAAIARAKAKKLAQANSASEAISNSQTAENEVEKTKSAVEKTQQNSTALDPKKAAVAAAIARAKAKKLAQANSTSEAISNSQTAENEVEKTKSAVEKTQENSTALDPKKAAVAAAIARAKAKKLAKTQATLENNQE
>NC_000907.1|WP_005650033.1|1753648_1754230_+|electron-transport-complex-subunit-RsxB
MTFLFIVITLLALIFGAILGFASIKLKVEADPVVEKIDAILPQSQCGQCGYPGCKPYAEAICNGDEITKCIPGGQTTIVKIAEILGVDVPTMEGIEEPIEKVAFIDENMCIGCTKCIQACPVDAIIGTNKAMHTIIPDLCTGCELCVAPCPTDCILMIPVKKNIDNWDWKFDAKLVIPVMNVDGSEKKLVVGE
>NC_000907.1|WP_005694403.1|1752982_1753561_+|electron-transport-complex-subunit-RsxA
MTHYILLIIGTALINNFVLVKFLGLCPFMGVSKKIETAVGMGLATMFVLTVASLCAYLVDHYILIPLNATFLRTLVFILVIAVVVQFTEMAINKTSPTLYRLLGIFLPLITTNCAVLGVALLNVNLAHNLTESVVYGFGASLGFSLVLVLFAALRERLVAADIPATFRGSSIALITAGLMSLAFMGFTGLVK
>NC_000907.1|WP_005694402.1|1751639_1752701_+|protease-SohB
MLNDILTGYGIFILEILTILLLILAVVGLIISYRQHNKSKVGELEIKDLSEEFNEQVRLLRDFNLSEEEQKQRTKAEKKAEKQNAKKRKEKLKKGETLEDEKKACVYVLDFCGDISASETTALREEISAILNVAKSEDEVLLRLESPGGIVHNYGFAASQLSRLKQKGIKLTVAVDKVAASGGYMMACVADKIVSAPFAVIGSIGVVAQIPNVHRLLKKHDVDVDVMTAGEFKRTVTVLGENTEKGKQKFQQELEETHKLFKQFVSQNRPCLDIDKIATGEHWFGQQAIALQLVDEISTSDDLILEKMKEKQVLNVKYRLKKSLIKKFGRQAEESAINIIHRYSTKQSRDFMY
>NC_000907.1|WP_005654151.1|1750776_1751442_-|DUF2057-domain-containing-protein
MKLRAVVLGLATLCTSTATFAGMVSTSSNLEFLAIDGQKASKSLGKAKTFTVDDTQNHQVVVRLNEIVGSGSNQSLFESNPVIVTFQGNAEDLVISAPVIRNLDSGDKFNQMPNITVKTKSGNAISAKVDVLKQEGLFPSGNVLNDLAEYNASGAAASVSKFAATTVASSVAVAPAGNAKANKGKVVVQGENVAEQQLQYWFQQADKETQTRFLNWAKSHK
>NC_000907.1|WP_005665016.1|1748552_1750709_-|TIGR01666-family-membrane-protein
MNIRLNAKVISTIPVFIAVNIAAVGIWFFDISSQSMPLILGIIAGGLVDLDNRLTGRLKNVFFTLIAFSISSFIVQLHIGKPIQYIVLMTVLTFIFTMIGAVGQRYSTIAFGSLVVALYTTLTYIPEVNVWFINPVMILCGTLLYSVVTLIVYLFFPNRPVQESVAKAFCALGEYLDTKSCFFDPDEVAEIEKKHLNFAMKNANVVTAFNIVRTALFYRIRGQHRHPLTQRMLRYYFAAQDIHERANSTHFDYQQITEKLKNTDLIFRIQRLLELQAQSCKEITASLRENKPYHFNKRVERALLGTLHSFDLYRAQHLNDQDELIDIQTLLDNLQSINWQLRQLAQDTTVTEQLAQIHTEQITGLKNISAVIFSHFTFESPLFRHAVRLSIVVFLCCAIVEFFQFNLGYWILLTTVFVCQPNYSATKVRLRQRIIGTILGVVVGSLLPYLNPTLELKLGLVVLTSTLFFFFRSNNYSFSTFFITLQVLLSFDVMGFDTAAALMPRLLDTLLGAAISWFAVSYLWPDWKYLQLDKVSHQALRSDAVYLLHIISQLQFGKSDDLKYRIARRNAHQYAAALSTTLSNMNNEPVKYKAYLQKGFDLLKLNYSLLSYISALGAYRDRMKNLQQTAQFLSGFYPVAKKIIYTLEHIEEIPEAIFNQQQESIETHLKELEKQEMTAEERAVFSLPYQQLNLITQLLPQFYGYFKKEINCQSAGAL
>NC_000907.1|WP_005665007.1|1747912_1748455_+|HAD-family-hydrolase
MQQKLENIKFVITDVDGVLTDGQLHYDANGEAIKSFHVRDGLGIKMLMDADIQVAVLSGRDSPILRRRIADLGIKLFFLGKLEKETACFDLMKQAGVTAEQTAYIGDDSVDLPAFAACGTSFAVADAPIYVKNAVDHVLSTHGGKGAFREMSDMILQAQGKSSVFDTAQGFLKSVKSMGQ
>NC_000907.1|WP_005654382.1|1759287_1759923_+|endonuclease-III
MNKTKRIEILTRLREQNPHPTTELQYNSPFELLIAVILSAQATDKGVNKATEKLFPVANTPQAILDLGLDGLKSYIKTIGLFNSKAENIIKTCRDLIEKHNGEVPENREALEALAGVGRKTANVVLNTAFGHPTIAVDTHIFRVCNRTNFAAGKDVVKVEEKLLKVVPNEFKVDVHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVEF
>NC_000907.1|WP_005694179.1|1759980_1761354_+|sodium-dependent-transporter
MTTNNKQRQTWSSRLTYVMTVAGATVGFGATWRFPYLVGENGGGAYVLLFCIAMIVIGIPMILVENVIGRRLRVNSIDAFGDKILDKGKGISKYWKILGYMGLLGAFGIMAYYMVLGGWVISYIISLISGTLDISTPITKDIAKNFYDLHIGNSPYEIIFYTLLFVIVNYIILAKGIIGGIERSVKYLMPLLFIFLIGMVIRNVTLPGAMEGITFYLKPDFSKITPQLFIFVLGQVFFALSLGFGVLITLSSYLNKEENLIHTAVITGFTNTIIAVLAGFMIFPSLFTFGIEPNAGPTLVFQSLPIVFSHLWAGKFFAIIFFGLLLIAALTTSITIYEVIITALQEKLRMCRGKAIVLTLSGIFLLGNIPAILGDNLWKNVTIFGKSIFDFYDYASGNILFMLTALGCAIFVGFVLKDEAKKELSSTKYSTFIKIWFNYVKFVVPLIILVIFISNLF
>NC_000907.1|WP_005694180.1|1761377_1762433_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MLQINVKKQLGQLALQANIQVPDQGVTAIFGLSGSGKTSLINLVSGLIQPDEGFICLNDRTLVDMESQESLPTHLRKIGYVFQDARLFPHYTVKGNLRYGMKNVSQDDFNYIVDLLGITHLLKRYPLTLSGGEKQRVAIGRALLTDPDILLMDEPLSALDVPRKRELMQYLERLSKEINIPILYVTHSLDELLRLADRVVLMENGIVKAYDRVEKIWNSPIFAPWKGESEQSSVLALPVHLHNPPYKMTALSLGEQVLWIHQVPANVGERVRVCIYSSDVSITLQKPEQTSIRNILRGKITQIEIQDSRVDLAVLVEGHKIWASISKWAQNELRFAIGQDVYVQIKAVSVM
>NC_000907.1|WP_005654374.1|1762419_1763148_-|molybdate-ABC-transporter-permease-subunit
MLTQFFSFFNLTPMEISAINLSLSVAVSSMLWSLPLAIFVAWLLARKNFYGKSLITGVIHLPLVLPPVVIGYLLLVAMGRNGFIGKYLYQWFGLSFGFSWKGAVLSSAVVAFPLVVRAIRLSLENIDIKLEQAAQTLGASAWRVFFTITLPLSLPGVLAGLVLGFARSLGEFGATITFVSNIAGETQTIPLAMYSFIQTPGAEEQTARLCLFAIILSLISLLLSEWLSKRMQKKLGQGNVAD
>NC_000907.1|WP_005694182.1|1763282_1764047_-|molybdate-ABC-transporter-substrate-binding-protein
MKKLTKISTALLIAGLGFSFAASAKVTVFAAASMTDALQQVAKDYAKQNPKNEVVFSFASSSTLAKQVEEGAPADIFVSASNKWMKYLSEKDLTVKETEKVLVGNDLVLIAPAKSAVNSVDIAKGEWINALKDSYLSVGDPAHVPAGQYAEEALTKLNLWDKVKDRLARGKDVRGALALVERAEAPYGIVYSTDAKVSQQVKTVAVFPADSHKPVVYPVSIVKGHDNADSRDFLKYLESDAAKKVLVGYGFSAK
>NC_000907.1|WP_005694183.1|1764184_1764952_+|TOBE-domain-containing-protein
MKNTEILLTIKLQQALFIDPKRVRLLKEIQQCGSINQAAKNAKVSYKSAWDHLEAMNKISPRPLLERNTGGKNGGGTALTTYAERLLQLYDLLERTQEHAFHILQDESVPLDSLLTATARFSLQSSARNQFFGRVAQQRIIDSRCVVDVNVQGLPTPLQVSITTKSSARLKLITEKEVMLMFKAPWVKISEQPLANQPNQFPVNIKSLNEEEAILQFAESNIEFCATVHQPNQWQIEQQVWIHIDQEQIILATLG
>NC_000907.1|WP_164927871.1|1765060_1765864_-|glycosyltransferase
MKFSVLMSLYIKENPQFLRECFESLVAQTRQADEIVLVFDGVVTPDLEFVVTEFETKLPLKLVKLPQNRGLGKALNEGLLHCDYDWVFRMDTDDICVPDRFEKQVAFIEQHPESIIFGGQIAEFGKNVNDIVAYRNVPTSAQEIIKFTQKRCPFNHMTVAYQKSAVINCGGYEDLQEDYYLWIKLVAQGLYMANLPDILVYARVGNGMVSRRRGVNQAKAEWRLFKLKYRLGIQGLLSGLFTFALRFGSRLLPTSLLKKLYQTFLRK
>NC_000907.1|WP_005694185.1|1765865_1766750_-|glycosyltransferase-family-2-protein
MLSIIVPSYNRKAEVPALLESLTQQTSSNFEVIIVDDCSKERVVVEQSYSFPVTVIRNETNQGAAESRNVGARTSKGDWLLFLDDDDCFMPEKCEKVLQVIEQNPNINFIYHPAKCEMVNEGFTYVTQPIEPQEISTERILLANKIGGMPMIAIKKEMFLKIGGLSTALRSLEDYDFLLKLLQEPSFTPYKINEPLTYCTFHTKRSSVSTDTTNTQKAIDYIREHYVKTVEQARNFDINASYILAYPHIMNLSRKAAKYYFDIFKKTKSIKQFIITLVILISPKLAINLKRLGK
>NC_000907.1|WP_005694186.1|1766761_1767535_-|glycosyltransferase-family-25-protein
MLKKYLISLDKDIQRRELFFSQKNTEDFQVFSAINTMQKDWDELAAIFNIEQFKAHYFRNVTKGEIGCTLSHLSVYQKIVEDNDIAEDSYALVCEDDALFHSDFQQNLTALLSEKLEAEIILLGQSKINDFNDFDLEINYPTTFSFLCKKTGDVNYAFPYKSYFAGTVGYLIKKSAARRFIQQISQNKPFWLADDFLLFEQNFNIRNKVVRPLIVIENPVLISNLESVRGSLSNNLLKKLMKYPLKKIFAIKKNLAN
>NC_000907.1|WP_005694187.1|1767546_1768608_-|glycosyltransferase-family-4-protein
MKKIGFFIMNIGSAGGTERVSINVANALAKQGYDVSFISIGGNKPFFQVDEKINIYAMNKLPYSLKKDYFSITKKLRELVKELQLDTLIVVDGAIMLFSALALVNLNIKHILWEHYSFNFTGNRLVRTLGKYLAVTTCDKIVTLTEAEKTLWQEKFKTNNIISIANPNTLLPKNKLAKLENKTILSVGHLFSYKGFDYLLKVWQVLAKKYPDWNLKIVGSGEEEENLKNLAKALDIEDSVNFIPRTNDVSFYYESSSIYCLPSQTEGLPLVVIEAMAFGLPIVAFNCSPGVKQLVEHKENGFLCEQNNIEEMVKGLDLLINNPELYLQMSDKSRLMSEDYGIEKIIEEWKGIL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1105411 : 1117497

Escherichia_phage(71.43%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010869113.1\|1105411_1106326_+	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	6.0e-26	30.6
WP_080003770.1\|1106471_1107911_-	meth protein	NA	NA	NA	NA
WP_032828348.1\|1107904_1108153_-	methionine synthase	NA	NA	NA	NA
WP_010869114.1\|1108430_1108931_-	ferredoxin-type protein NapF	A0A077SLP0	Escherichia_phage	3.8e-14	32.6
WP_005693380.1\|1108930_1109542_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	1.0e-21	32.5
WP_005693381.1\|1109653_1110493_-	dimethyl sulfoxide reductase anchor subunit	A0A077SK59	Escherichia_phage	5.5e-18	31.4
WP_005656008.1\|1110494_1111112_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	2.2e-72	56.8
WP_005693382.1\|1111122_1113543_-	molybdopterin-dependent oxidoreductase	A0A077SK27	Escherichia_phage	4.8e-224	50.6
WP_010869115.1\|1113796_1114906_+	transglutaminase family protein	NA	NA	NA	NA
WP_010869116.1\|1114947_1115241_+	membrane protein	NA	NA	NA	NA
WP_005662887.1\|1115249_1115528_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_005686318.1\|1115652_1117497_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	2.8e-22	29.3

DBSCAN-SWA_2

1500121 : 1513073

Haemophilus_phage(45.45%)

terminase,holin,integrase

attL 1498816:1498829|attR 1513211:1513224

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1498816:1498829	attL	NA	NA	NA	NA
WP_005693957.1\|1500121_1501222_-	DUF2213 domain-containing protein	Q7Y5U2	Haemophilus_phage	3.1e-138	85.9
WP_005693956.1\|1501282_1501639_-	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_005693954.1\|1503393_1504704_-	DUF1073 domain-containing protein	Q7Y5U6	Haemophilus_phage	1.3e-210	84.2
WP_005693952.1\|1506034_1506550_-\|terminase	terminase small subunit	A0A1X9SFE5	Acinetobacter_phage	5.6e-21	40.9
WP_010869207.1\|1506559_1507081_-	Rha family transcriptional regulator	A0A0P0HSR5	Acinetobacter_phage	2.8e-20	34.9
WP_005693951.1\|1507208_1507490_-	hypothetical protein	Q776X1	Haemophilus_phage	9.4e-31	73.3
WP_005693950.1\|1507401_1507677_-	DUF2570 family protein	Q7Y5U9	Haemophilus_phage	2.5e-12	47.2
WP_005693948.1\|1507669_1508272_-	glycoside hydrolase family 19 protein	Q7Y5V0	Haemophilus_phage	2.1e-56	53.4
WP_005650535.1\|1508240_1508597_-\|holin	phage holin, lambda family	NA	NA	NA	NA
WP_165442161.1\|1508720_1508858_-	hypothetical protein	NA	NA	NA	NA
WP_005693946.1\|1509961_1510261_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	7.9e-20	45.3
WP_005643896.1\|1510257_1510551_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	8.3e-14	46.6
WP_050396694.1\|1510581_1510944_-	hypothetical protein	NA	NA	NA	NA
WP_005693944.1\|1511012_1511588_+	hypothetical protein	A0A0M3LQ72	Mannheimia_phage	5.2e-52	55.2
WP_005693943.1\|1511873_1512158_+	hypothetical protein	NA	NA	NA	NA
WP_005693942.1\|1512158_1513073_-\|integrase	site-specific integrase	A0A0M3LQN1	Mannheimia_phage	1.5e-80	52.2
1513211:1513224	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1558773 : 1597183

Shigella_phage(29.41%)

tail,head,capsid,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005645090.1\|1558773_1559373_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	5.3e-15	30.6
WP_005693492.1\|1559961_1560681_-	helix-turn-helix transcriptional regulator	F6MII3	Haemophilus_phage	1.0e-65	53.1
WP_005693493.1\|1560908_1561178_+	transcriptional regulator	F6MII4	Haemophilus_phage	4.6e-19	60.5
WP_010869221.1\|1561211_1563275_+\|transposase	transposase	A0A2P9JZG7	Alteromonadaceae_phage	2.6e-125	42.9
WP_005693495.1\|1563331_1563604_+	hypothetical protein	NA	NA	NA	NA
WP_005693497.1\|1563536_1564007_-	hypothetical protein	NA	NA	NA	NA
WP_010869222.1\|1564040_1564904_+	AAA family ATPase	M4M9P4	Vibrio_phage	1.9e-61	44.3
WP_010869223.1\|1564964_1565282_+	hypothetical protein	A0A0M3LQH1	Mannheimia_phage	1.1e-16	50.5
WP_005693500.1\|1565296_1565806_+	nuclease inhibitor	F6MIJ0	Haemophilus_phage	1.6e-65	77.7
WP_005693501.1\|1565802_1565964_+	hypothetical protein	NA	NA	NA	NA
WP_164927869.1\|1565963_1566233_+	hypothetical protein	NA	NA	NA	NA
WP_005693504.1\|1566435_1566657_+	ANR family transcriptional regulator	NA	NA	NA	NA
WP_005693505.1\|1566656_1566830_+	hypothetical protein	NA	NA	NA	NA
WP_005693506.1\|1566832_1567393_+	DUF5420 family protein	A0A0M3LP85	Mannheimia_phage	7.2e-22	35.2
WP_010869224.1\|1567566_1568124_+	gp16 family protein	A0A2I7S9B8	Vibrio_phage	4.2e-14	30.6
WP_005693508.1\|1568120_1568675_+	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	8.3e-47	54.6
WP_005693510.1\|1569308_1569815_+	hypothetical protein	A0A1I9KF52	Aeromonas_phage	1.9e-13	33.5
WP_005693512.1\|1570447_1570708_+	DUF2644 domain-containing protein	F6MIK0	Haemophilus_phage	1.8e-12	56.7
WP_005693513.1\|1570704_1570959_+	DUF2681 domain-containing protein	NA	NA	NA	NA
WP_005693516.1\|1571076_1571304_+	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
WP_032828368.1\|1571303_1571630_+	DUF2730 domain-containing protein	NA	NA	NA	NA
WP_010869227.1\|1571634_1571943_+	hypothetical protein	A0A2I7S9D8	Vibrio_phage	1.3e-17	61.5
WP_010869228.1\|1571954_1572524_+	DUF3486 family protein	A0A2I7S9D1	Vibrio_phage	7.2e-38	44.3
WP_005693520.1\|1572523_1574050_+	hypothetical protein	A0A2I7S9C5	Vibrio_phage	1.0e-158	58.7
WP_010869229.1\|1574061_1575624_+	DUF935 domain-containing protein	A0A0C4UQR8	Shigella_phage	9.9e-146	53.1
WP_010869230.1\|1575714_1576959_+\|capsid	minor capsid protein	C9DGN7	Escherichia_phage	1.4e-81	40.9
WP_005693523.1\|1577096_1577537_+	phage virion morphogenesis protein	NA	NA	NA	NA
WP_005693524.1\|1577767_1578835_+	hypothetical protein	A0A0C4UQU6	Shigella_phage	4.3e-76	47.8
WP_005693526.1\|1578834_1579761_+\|head	phage head protein	A0SMP3	Pseudomonas_virus	1.3e-76	52.9
WP_032828369.1\|1580234_1580657_+	gp436 family protein	A0A0C4UR02	Shigella_phage	7.5e-16	37.6
WP_005693530.1\|1580656_1581208_+	DUF1834 family protein	A0A0C4UQU7	Shigella_phage	2.6e-32	42.0
WP_005693531.1\|1581220_1581412_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_005693532.1\|1581411_1582875_+\|tail	phage tail sheath protein	A0A0C4UQS0	Shigella_phage	6.3e-118	46.6
WP_005693533.1\|1582884_1583241_+\|tail	phage tail tube protein	A0A0C4UQZ1	Shigella_phage	4.3e-12	36.0
WP_005693534.1\|1583253_1583637_+	hypothetical protein	C9DGP9	Escherichia_phage	5.6e-18	49.6
WP_010869233.1\|1583717_1585613_+	tape measure domain-containing protein	A0A2I7S9D9	Vibrio_phage	2.2e-54	33.7
WP_010869234.1\|1585612_1586980_+	DNA circularization protein	A0A0C4UR32	Shigella_phage	8.4e-40	29.8
WP_164927870.1\|1586979_1587765_+\|tail	phage tail protein	A0A0C4UQS1	Shigella_phage	1.9e-44	37.9
WP_005693539.1\|1588276_1588825_+\|plate	phage baseplate assembly protein V	A0A2I7S9F6	Vibrio_phage	4.7e-26	44.0
WP_005693540.1\|1588833_1589241_+	hypothetical protein	A0A0C4UR04	Shigella_phage	2.3e-22	43.3
WP_005693541.1\|1589240_1590308_+\|plate	baseplate J/gp47 family protein	A0A0C4UQU9	Shigella_phage	4.6e-70	43.1
WP_165442165.1\|1590333_1590900_+	YmfQ family protein	A0A2I7S9L6	Vibrio_phage	1.3e-23	34.6
WP_005693543.1\|1590899_1592771_+\|tail	phage tail fiber protein	A0A0M3LRW6	Mannheimia_phage	2.8e-46	45.2
WP_005693545.1\|1593254_1593374_+	Com family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_032828356.1\|1593429_1594275_+	hypothetical protein	F6MIM2	Haemophilus_phage	2.6e-116	72.1
WP_005693547.1\|1594828_1595566_-	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005693548.1\|1595752_1597183_-	bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE	E3SJ88	Synechococcus_phage	4.1e-21	44.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_000907

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection