CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017298	Clostridium botulinum F str. 230613 plasmid pCBF, complete sequence	0 crisprs	NA	0	0	0	0
NC_017297	Clostridium botulinum F str. 230613, complete genome	15 crisprs	csa3,DinG,c2c9_V-U4,WYL,DEDDh,cas3,cmr6gr7,cmr5gr11,cmr4gr7,csx1,cmr3gr5,cas10,cmr1gr7,cas6,casR,cas3HD	3	17	6	0

1. NC_017297

CRISPR-Cas detection and classification

Crispr_ID: NC_017297_1

• CRISPR_ID: NC_017297_1
• CRISPR_location: 1046093-1046380
• CRISPR_type: Orphan
• Repeat_type: III-B
• Spacer_info: 4 spacers

Consensus repeat of NC_017297_1

Consensus_repeat	Method
TGAACATTAACATGAGATGTATTTAAAT	CRISPRCasFinder

spacers of NC_017297_1

>1.1|1046121|38|NC_017297|CRISPRCasFinder
TCTTGAGTAAAAAATAAAACCTCATGTCCTTCTAGGGC
>1.2|1046187|37|NC_017297|CRISPRCasFinder
GATACCTGTTGTGTAAGTTTAGCTATCTCTGGATTGT
>1.3|1046252|37|NC_017297|CRISPRCasFinder
ATATATGCACTACGGTGTTTTACATTATTCGGACTAT
>1.4|1046317|36|NC_017297|CRISPRCasFinder
AAGGTAGATATGGCCATATCTACTTGCGGAGCCTAT

CRISPR arrays and Neighbor proteins around NC_017297_1

CRISPR arrays

The CRISPR arrays of NC_017297_1

>merge|NC_017297|1|1046093-1046380|CRISPRCasFinder
TGAACATTAACATGAGATGTATTTAAATTCTTGAGTAAAAAATAAAACCTCATGTCCTTCTAGGGCTGAACATTAACATGAGATGTATTTAAATGATACCTGTTGTGTAAGTTTAGCTATCTCTGGATTGTTGAACAATAACATGATATGTATTTAAATATATATGCACTACGGTGTTTTACATTATTCGGACTATTGAACATTAACATAGGATGTATTTAAACAAGGTAGATATGGCCATATCTACTTGCGGAGCCTATTGAACAATAACATAAGATGTATTTAAAT

>NC_017297|1|1|1046093-1046380|CRISPRCasFinder
TGAACATTAACATGAGATGTATTTAAAT	TCTTGAGTAAAAAATAAAACCTCATGTCCTTCTAGGGC
TGAACATTAACATGAGATGTATTTAAAT	GATACCTGTTGTGTAAGTTTAGCTATCTCTGGATTGT
TGAACAATAACATGATATGTATTTAAAT	ATATATGCACTACGGTGTTTTACATTATTCGGACTAT
TGAACATTAACATAGGATGTATTTAAAC	AAGGTAGATATGGCCATATCTACTTGCGGAGCCTAT
TGAACAATAACATAAGATGTATTTAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_003404069.1|1057705_1058680_+|porphobilinogen-synthase	unknown	unknown	gnl|CDD|236450
NC_017297.1|WP_011987841.1|1051898_1052618_+|energy-coupling-factor-ABC-transporter-permease	unknown	unknown	gnl|CDD|181384
NC_017297.1|WP_011987835.1|1042813_1043359_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017297.1|WP_011987839.1|1049445_1050408_+|cobalamin-biosynthesis-protein	unknown	unknown	gnl|CDD|234919
NC_017297.1|WP_011987842.1|1052621_1052921_+|energy-coupling-factor-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|179494
NC_017297.1|WP_011987829.1|1033269_1034877_+|hypothetical-protein	unknown	unknown	gnl|CDD|372624
NC_017297.1|WP_079992165.1|1038428_1039460_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_017297.1|WP_014519207.1|1035240_1037601_-|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl|CDD|213222
NC_017297.1|WP_079992166.1|1054014_1054677_+|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235504
NC_017297.1|WP_011987840.1|1050626_1051715_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|180542
NC_017297.1|WP_011987845.1|1054645_1055518_+|hydroxymethylbilane-synthase	unknown	unknown	gnl|CDD|234612
NC_017297.1|WP_134865364.1|1045878_1046031_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_011987836.1|1043438_1045034_+|LexA-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224885
NC_017297.1|WP_011987843.1|1052883_1053582_+|cobalt-ECF-transporter-T-component-CbiQ	unknown	unknown	gnl|CDD|274139
NC_017297.1|WP_011987847.1|1057261_1057444_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_011987834.1|1040764_1042471_+|hypothetical-protein	unknown	unknown	gnl|CDD|276807
NC_017297.1|WP_011987837.1|1046491_1047256_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133381
NC_017297.1|WP_011987831.1|1037760_1038432_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_017297.1|WP_041173203.1|1039811_1040360_+|biotin-transporter-BioY	unknown	unknown	gnl|CDD|376871
NC_017297.1|WP_003401789.1|1045312_1045870_+|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	unknown	unknown	gnl|CDD|235612

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_011987835.1|1042813_1043359_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.40542e-18
NC_017297.1|WP_011987839.1|1049445_1050408_+|cobalamin-biosynthesis-protein	gnl|CDD|234919	PRK01209, cobD, cobalamin biosynthesis protein.	5.58477e-152
NC_017297.1|WP_011987842.1|1052621_1052921_+|energy-coupling-factor-ABC-transporter-substrate-binding-protein	gnl|CDD|179494	PRK02898, PRK02898, energy-coupling factor ABC transporter substrate-binding protein.	1.87777e-41
NC_017297.1|WP_011987829.1|1033269_1034877_+|hypothetical-protein	gnl|CDD|372624	pfam13520, AA_permease_2, Amino acid permease.	0.00267979
NC_017297.1|WP_079992165.1|1038428_1039460_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.35888e-60
NC_017297.1|WP_014519207.1|1035240_1037601_-|ABC-transporter-ATP-binding-protein/permease	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	8.63364e-112
NC_017297.1|WP_079992166.1|1054014_1054677_+|NAD(P)-dependent-oxidoreductase	gnl|CDD|235504	PRK05562, PRK05562, NAD(P)-dependent oxidoreductase.	1.76332e-105
NC_017297.1|WP_011987840.1|1050626_1051715_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|180542	PRK06358, PRK06358, threonine-phosphate decarboxylase; Provisional.	2.99757e-88
NC_017297.1|WP_011987845.1|1054645_1055518_+|hydroxymethylbilane-synthase	gnl|CDD|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	3.06751e-147
NC_017297.1|WP_011987841.1|1051898_1052618_+|energy-coupling-factor-ABC-transporter-permease	gnl|CDD|181384	PRK08319, PRK08319, energy-coupling factor ABC transporter permease.	1.90965e-119
NC_017297.1|WP_011987836.1|1043438_1045034_+|LexA-family-transcriptional-regulator	gnl|CDD|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	1.7046e-33
NC_017297.1|WP_011987843.1|1052883_1053582_+|cobalt-ECF-transporter-T-component-CbiQ	gnl|CDD|274139	TIGR02454, Uncharacterized_protein_MJ1089, cobalt ECF transporter T component CbiQ. This model represents the CbiQ component of the cobalt-specific ECF-type. CbiQ is now recognized as the T component of energy-coupling factor (ECF)-type transporters. The S component confers specificity (CbiM-N for cobalt systems), which CbiO is the ABC-family ATPase. In general, proteins found by this model reside next to the other putative subunits of the complex, identified as CbiN, CbiO, or CbiM. Note that the designation of cobalt transporter has been spread excessively among ECF system transporters with many other specificities. [Transport and binding proteins, Cations and iron carrying compounds].	5.20956e-28
NC_017297.1|WP_003404069.1|1057705_1058680_+|porphobilinogen-synthase	gnl|CDD|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NC_017297.1|WP_011987834.1|1040764_1042471_+|hypothetical-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	7.34293e-42
NC_017297.1|WP_011987837.1|1046491_1047256_-|MerR-family-transcriptional-regulator	gnl|CDD|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	1.88537e-49
NC_017297.1|WP_011987831.1|1037760_1038432_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.12644e-65
NC_017297.1|WP_041173203.1|1039811_1040360_+|biotin-transporter-BioY	gnl|CDD|376871	pfam02632, BioY, BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes.	5.52339e-40
NC_017297.1|WP_003401789.1|1045312_1045870_+|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase	gnl|CDD|235612	PRK05800, cobU, adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Validated.	2.20709e-84

Protein sequences

>NC_017297.1|WP_134865364.1|1045878_1046031_-|hypothetical-protein
MLKNFFQPFAIFYKDRDKAYLKAYISMPRIYFKIKCGLKILLLIIRLISY
>NC_017297.1|WP_003401789.1|1045312_1045870_+|bifunctional-adenosylcobinamide-kinase/adenosylcobinamide-phosphate-guanylyltransferase
MSDKNKVALITGGVRSGKSEFAESLLQNEKSVLYIATAKITDKEMEHRVEKHKERRNSTWKTYEGYKDLGKIIKYYDEKNILLDCVTVMTTNLMFHKKIDYENIKEEQLDEILEGIKKEFYDLIISVKEENKNIILVTNEVGYSIVPAYKLGRIFRDFQGIINKFIASLSDEVYLVTCGIPLKIK
>NC_017297.1|WP_011987836.1|1043438_1045034_+|LexA-family-transcriptional-regulator
MKLESGQNRIVKSKHLGYGLLRGSLGTGKTTAAIYRGIYLKNQYCMYDKDKVLILSKHEENLNYIKNIYDEAEKTGVQYITLFSYIEDKLYFSVIYKIINKYFWEYIENNNLQCKIASEEEKRAIIEECINDIKNEYKKLKYIDIKYSKFFLEEIQWMKDCMYYELEEYKKADRIGRKTKKGEGPQRIIKNSKIREAVFKIMLLYNEKLKDKNLLDYSDVVSMALKEASKNKENKFNHIIVDEAQNFTKLELKFIEALGRKNIYSSILFIADKEKNSNPKGWITKGRKLNNLQLGFEFKRFNLNKKVSINLKKNIDDCNLKRKVSNIDTKNEAVSNIDNANLEDKVLDKNIKNEWHKDRVNYDMDKFEYVDMKHRRSYEFSRGLGSNEEFIVEDQGSKEEYKEDELTKLPVFNDIAAGEPILMNPCVEGEFNIPKYWVRGMKNCFILKVKGDSMIGANIEDGDHVVIKRQQMAENKDIVAVNLEGSATLKRLLIKKSGAVLMPENKKYKPIEIREEGASIIGIAVGIIKGK
>NC_017297.1|WP_011987835.1|1042813_1043359_+|GNAT-family-N-acetyltransferase
MGKIKQAKYNINGKTIIIRHAEVQDAEQLINVTKKVNQETDFLLKDPEEVCLTIKEEKEFIQSQIDSQVDLLIVPEIDGRIVGICSLNGNTNKRIRHCAQFGLAVEKEYCGMGIGKNLMKSGIEWAKENGIFRITLEVDINNYRAISLYLKLGFEIEGTLRNDKMLLDGSYTSGYAMALLL
>NC_017297.1|WP_011987834.1|1040764_1042471_+|hypothetical-protein
MDRFSFLKIEWPEIYQIICNVEEKSKEDSNTTLIKLAQIAELITKYILKENHIEKNTELLDEINLLRDCYNLNDNIADFFYKIIIVSNKAIYENYSDSIIAKSFLDKMFEILVWFAIEYGKTDYRKVDLSNMIPEDKDIFNKYIKSKSYNDTEKNIENETMIQPFTIDNEEFFKEENNDDINRYEQDIFETKEEFHKRIKDHEIFTLGRIFIKKSNINGTDEIVAFPFSVYKSIQIKIPIIDMLYIERAEFENLSIEEEEYTVFSKLDIINDKICIDINNIYIGVNNNKCKVHAVVLDVSYYESYEKYRNIIYSKKSIPIGMIKLNKNKYDINKNEMPVTINYYDWIQKYILNTKAYIEIDRYEAKTLCKENLYYILNGKLDIFDKKLLIREYYIQSKSLDKNFRINLHSSDTMNKLRCLVDKEEILAMNIIGEMYYKEQNYKEAMYWYKKASEKGNSTSMNKIGVMYYEGKGVEQDYKKAMYWYKKSSQEGNFTAMSNIGFMYYSGQGVTQDYKKAMYWYKKSYKEGNSGVMRDIGSMYYEGKGVIKDYKKAMQCYKKASQIDNFIK
>NC_017297.1|WP_041173203.1|1039811_1040360_+|biotin-transporter-BioY
MDKKLKVRDMIYSALFATIIGVSSYIIIPLPISPVPITAQSLAVMLAGCVLTPIQVVLSMITFLLMGIIGIPVFSGGTAGFGIIVGKTGGYLIGFLVGAIIISLLVRKNKSLVNMMIACFIGGIVVVHILGSAWLGQVTSIGIKKAFLLGSAPFIPGDLIKAVVAVLIGRKLSKEMKRIGTQ
>NC_017297.1|WP_079992165.1|1038428_1039460_+|HAMP-domain-containing-histidine-kinase
MMNNKISVKMVVAFSLIVFFIVTSAVVISALVVVFLSRFNVFTQPNPLILLGWLGIISIMVSTAIAQIIGKKVLSPISDLNKATKEVAKGNFNTRLSENSWTDEIREMAHSFNIMTHELGNIETLRDDFISNVSHEFKTPISAIEGYATLLQDDELSDEERKEYIHKILISTKRLSSLSGNILQITELENQKILPLKQKYYLDEQIRQTILLFEYQWTKKNITLDINLDNITYIGSKELLAQVWQNILGNAIKFSHQNGTIQVTLTQTNEEVLITIKDNGIGMSEEVKDRVFEKFYQGDSSHYSDGNGLGLALVKRIIDICEGTIKISSHEEVGTEFTVKLPK
>NC_017297.1|WP_011987831.1|1037760_1038432_+|response-regulator-transcription-factor
MFRVLVVEDDPALRKLFCTVLNKNGYKSIEAKDGDSALDILYREYIDLIISDIMMPNMDGYTLTKLIRESNNNVPILMITAKETFSDKQEGFRVGTDDYMVKPIDVNEMILRVGALLRRSQIINERKIVIGETTFLYDFLSVKYNNKELVLPQKEFYLIYKLVSTPNKIFTRQQLMDEIWGIESETDPRTVDVHINRLRDRFKDNKDFNIITIRGLGYKVVKQ
>NC_017297.1|WP_014519207.1|1035240_1037601_-|ABC-transporter-ATP-binding-protein/permease
MLQIKDLKKVYTTGEFKQTALDGVSIDFRQSEFVAILGPSGSGKTTLLNMLGGLDQYDSGDMIINGLSTKKFGESDWDTYRNNSVGFIFQSYNLIPHLSIVDNVEMGMTLSGVPKSEKRQKATYVLEKVGLGNHIHKKPNQLSGGQMQRVAIARALANDPEIILADEPTGALDTQTSQQIMDLIKEIAKDKLVIMVTHNPELAEEYADRIVSFSDGKIVSDTNPFVSENNSNDYKPKKTSMNFLTALKLSGNNIVTKKWRTALTAFASSIGIIGVALVLSLSNGFNKQINEFEKDSLSNYPISIEQNSMSLGMSPSSKSKDKEKTEFPNKSMIYPYDSSKNATVHANAISTEYVDYIKKIDSSLINGISYTRNVNMNILKKQDGKVVSMNTSAAAFSTYPSKGDSFETDYLKSYYDVLAGSYPKNEKELVLVVDKYNQVDTNILEALGFSANSKNINFDSMIGTEYKLIYNDDYYTQSGKYFTVNGDTTNLENLYNNKNAVTLKISGIIRIKEDANVSNLSTGIVYSDQLAQDFIENAKNSKIVLAQKEAKYNVMNGNLLTEKTSTTTAAVHGAPNMTTNITSNVETKDDVLASLGATSSPTSISIYPVNFEAKDNITNYLDDWNKKLKEEDQIVYTDMASMITSLTGNIMDGITIVLVAFAGISLVVSMIMIGIIIYISVLERTKEIGVLRALGARKKDITRVFNAETFIIGFCSGGLGIAITYLLTIPVNSILYKFTDLNNVAQLNPLHAIALVITSIVLTMIGGAIPSKMAAKKDPVIALRSE
>NC_017297.1|WP_011987829.1|1033269_1034877_+|hypothetical-protein
MKKKIYSSFIVLSLIISMALIYFLMPVFSVKFYSFYIVFIIIALLLSINVSLNKGKESSKIYGIPVILIGLFIVMFIISLPIFRASSYKKLLPTPKYEEFSKNITPIDIKEIPTVNQKYAELLADKKLGEETSLGSKVELGTLTLQNVNGKLYYVAPLVHSGFMKWLLNDSTPGYITVSATDDKDVKLVTKLNGKDIKIRYQPKGFLNDDLKRHIYLKGTMNKGITDLTFELDDKGNPYYTATIYENKVGMSGQKAVGTAIVNPETGEVKKYTVENTPKWVDRIQPQSFVENNLKKWGKYIKGFFNFSGQDKLKATEGTGVIYNNDRCYYYTGLTSVGKDESSIGFALVDTRTQQTRIFKIAGATETASMKSAEGKVQNLGYTSTFPILINVDNIPTYFTTLNDKNDLTKMFAMISVTDYNIIGTGENITECKSNYIKNLASKGNLINVGSTGKEENITDTIERINSYVVGNSTIYTFILKDHKDKIFNAGISISNELPITKEGDKVNIRYVDTKQDTINITSFDNIEFKQQSIK
>NC_017297.1|WP_011987837.1|1046491_1047256_-|MerR-family-transcriptional-regulator
MHYKIKEVADMAGISVRMLHHYDKIGLLHPESVSAAGYRLYSDENLDRLQQILFFKELNFPLQEIKIILDSPNFDKKEALKVHRQLLLEKKIRLEKIIQSVDKTISNMEGEFKMDKKETLNVFSMTEIEEHQRKYSEEIKEKYGNTSAYKESNKKTSKYTKEDWSNIMKGWDEIFKKLANLMDKNPDDKEVQESVHQFREHISKNFYDCTPEIFRGLGELYVNDERFTTNIDKYKTGLSKFLKEAINVYCDNIK
>NC_017297.1|WP_011987839.1|1049445_1050408_+|cobalamin-biosynthesis-protein
MYLNVTGNFIDIIIAIFIDWIIGDPYWFPHPVIYIGKLINFLEKKFRARVKNEENLKIYGEVIVMIVCFASFLIPFMILQAFKFNFYIYHGLNILIIWTTLAAKCLHEEAIKIYYALYKENIEEARLKLSYIVGRETKDLIGNEIMRADIETVAENASDGVIAPLFYAIIGGAPLAMMYKGINTMDSMLGYLNDKYRYIGFFPAKVDDIFNFIPARLTGILMCISAPIVGGNPFKSFKIMIRDRKNHKSPNCAYPEGATAAALKIQLGGTNVYFGQVVEKPTIGDKIKELAPIHIKESIKLMYASEALMIVMCAIIFKLF
>NC_017297.1|WP_011987840.1|1050626_1051715_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MHGGDIYTEGILKGKELIDFSSNINPLGLSDSFKDNLEEALSWVQVYPDIQYRNLKRNLIDYLSFSLGYFYKEKVEKPNIKEENLVLGNGAVEIIDLAISNLKSISILVPSFVEYELCAKKWNVQIDYCNLNEDMTYNYENIKKSLEKTEGIILGNPNNPNGSVIDKESFIYILDYCEKNNKIVILDEAFIEFTGKNSFSFLNLYKRYKCIFIIRALTKFFSMPGIRFGYGISFNNEFLNKIREKQNPWNINCFAEIAVKYVLKDEEFIEKSINYIEKERTFMYENLKKSHLFHDVYSTYSNFILCKLKRITGEELKEKLLDKGFVLRICKDFKTLNDDYVRFAIKTRELNKNLIHVLKEIN
>NC_017297.1|WP_011987841.1|1051898_1052618_+|energy-coupling-factor-ABC-transporter-permease
MKKKYLFLLTTALVLALSQSAYAMHIAEGFLPPKWAALYFVLSAPFIVIGIKHIRQKTKKNKDLKMLLAVVAAYAFILSAMKIPSVTGSCSHPTGTGLAAIIFGPFVASVVGVIVLLFQAILLAHGGITTLGANTFSMGIVGPIVSYLIYKGLKNKNQKLAVFLAASLGDLATYTVTSLQLALSFPAKTGGAMAAFAKFATIFSLTQIPLAIIEGLITIMIFDFMMKYSKEELKTLSEV
>NC_017297.1|WP_011987842.1|1052621_1052921_+|energy-coupling-factor-ABC-transporter-substrate-binding-protein
MKKQNIIITIVSVVVILASLFIGGARGGEFAGADDQAEGIIEEMNKNYEPWFESIWEPPSGEIESLLFASQAALGAGVIGYYIGKKKNAKNNNASIKNQ
>NC_017297.1|WP_011987843.1|1052883_1053582_+|cobalt-ECF-transporter-T-component-CbiQ
MLRTIMLLSKTSKLSNIHPLEKAILSIIPIVILGFTQNYIIVFCNILFFLFMNFISKNNKKIFTKITLEVTAFAAISSITFVFDYGIVYTLTLIFKSVSAGLCLSFFSLTTPIDDMLYCLGKKEYLKDMCDIAKGMERFLVVINDEYNILYSSIKSRGGFDSFKLKIRNTGKMAALLFINTLSRWKIIKEGLDSRGYVGYVPYLDRDFDFSYIRFFSILSYIILMLLLVIFF
>NC_017297.1|WP_079992166.1|1054014_1054677_+|NAD(P)-dependent-oxidoreductase
MEWINLQEKYNFIALKSKRIRILIVGGGRAAFIKGKSFLDRGCSLYMLAPKFSKGVLDLKNYDNVEFIKNNYDEKYILDKHLVVIATEDEEVNNEIRNNCDALSKLYIDCSDKDKSLCFNSFQRESKTMVLALNNKIGCPKATSFIGEKIKRDLEKYDNYIEYVTYIRSITKNNTMKDEIIDFICSNDFHFFFEKGYGNLILSMFYGGMDFEFYNSHKKK
>NC_017297.1|WP_011987845.1|1054645_1055518_+|hydroxymethylbilane-synthase
MNFIIATRRSKLAQVQTEIIIDLLNKKHDIECEKLLIETVGDKILEVSLDKIGGKGLFVKDIEVAMLEQRADAAVHSMKDVPYEMPKGFEIIAIPKREDVRDAFISLDNIKFKDLRKGAKIGTSSRRRAAQLKLLRPDLDIVPIRGNVQTRIEKIKKENLDGIILAVAGLKRVNLEHLITDYFDTKEMVPAIGQGALGIEVMEEHPKKELFKDLDHYNSKICVLAERAFMRELDGDCHSTIGAYASIKDNIMHIIGIFERKNKIIKKEITGTKDQYEKLGIALAEHILKD
>NC_017297.1|WP_011987847.1|1057261_1057444_+|hypothetical-protein
MENNKKCPICGCEEIGEGKLESYMAPTDGSWLSSKVIADICTKCGHILAMRVKNPEKFKD
>NC_017297.1|WP_003404069.1|1057705_1058680_+|porphobilinogen-synthase
MFRRHRRLRENEAIRAMVRETVIREEDFIYPMFVVEGENIKEEISSLPGNYHYSIDRLEELVEEVKKSGIKGIMIFGVPDHKDECGSAAFDDNGIVQKGIRRLRELMPELYIVADVCMCQYTSHGHCGIIHGHNVDNDESLKYLAKISLSYAKAGADMIAPSDMMDGRVYAIRKILDENNFKHVGIMAYSAKYCSAFYGPFREAANSAPQFGDRKTYQMDPANGREAMLEIEDDINEGADIVMVKPALPYLDVIRMAKDRFEFPLAAYNVSGEYAMVKAAAKQGLIDERRVALEMLTSIKRAGADIIITYYAFEASAWLKEDRK

Crispr_ID: NC_017297_2

• CRISPR_ID: NC_017297_2
• CRISPR_location: 1109484-1109576
• CRISPR_type: Orphan
• Repeat_type: III-B
• Spacer_info: 1 spacers

Consensus repeat of NC_017297_2

Consensus_repeat	Method
GTTGAACATTAACATGAGATGTATTT	CRISPRCasFinder

spacers of NC_017297_2

>2.1|1109510|41|NC_017297|CRISPRCasFinder
AAATTCTATTTTACGAATTATTTTATTTGTCATCTTAAAAG

CRISPR arrays and Neighbor proteins around NC_017297_2

CRISPR arrays

The CRISPR arrays of NC_017297_2

>merge|NC_017297|2|1109484-1109576|CRISPRCasFinder
GTTGAACATTAACATGAGATGTATTTAAATTCTATTTTACGAATTATTTTATTTGTCATCTTAAAAGGTTGAACATTAACATGAGATGTATTT

>NC_017297|2|2|1109484-1109576|CRISPRCasFinder
GTTGAACATTAACATGAGATGTATTT	AAATTCTATTTTACGAATTATTTTATTTGTCATCTTAAAAG
GTTGAACATTAACATGAGATGTATTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_011987909.1|1116671_1116974_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_011987910.1|1117179_1117935_+|DUF4184-family-protein	unknown	unknown	gnl|CDD|379379
NC_017297.1|WP_011987908.1|1114038_1116198_+|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl|CDD|224428
NC_017297.1|WP_011987900.1|1105393_1105987_+|DUF1349-domain-containing-protein	unknown	unknown	gnl|CDD|377771
NC_017297.1|WP_011948678.1|1120503_1120935_+|ferritin	unknown	unknown	gnl|CDD|153105
NC_017297.1|WP_011987911.1|1118202_1120332_+|DNA-helicase-RecQ	unknown	unknown	gnl|CDD|273594
NC_017297.1|WP_011987901.1|1106050_1106251_+|DUF3788-family-protein	unknown	unknown	gnl|CDD|378906
NC_017297.1|WP_011987904.1|1107687_1108542_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017297.1|WP_011987898.1|1102852_1103890_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378400
NC_017297.1|WP_011987907.1|1111843_1114012_+|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl|CDD|224428
NC_017297.1|WP_003355968.1|1122398_1122782_+|response-regulator	unknown	unknown	gnl|CDD|381110
NC_017297.1|WP_011987903.1|1107318_1107642_+|TfoX/Sxy-family-protein	unknown	unknown	gnl|CDD|225612
NC_017297.1|WP_011987913.1|1122896_1125371_+|DUF3298-domain-containing-protein	unknown	unknown	gnl|CDD|378702
NC_017297.1|WP_011987896.1|1099634_1101395_-|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl|CDD|237723
NC_017297.1|WP_011987914.1|1125818_1126034_+|DUF2997-domain-containing-protein	unknown	unknown	gnl|CDD|314207
NC_017297.1|WP_011987897.1|1101405_1102536_-|glycerol-dehydrogenase	unknown	unknown	gnl|CDD|181843
NC_017297.1|WP_011987902.1|1106372_1107218_+|aldo/keto-reductase	unknown	unknown	gnl|CDD|381383
NC_017297.1|WP_011948662.1|1104797_1105241_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NC_017297.1|WP_011987912.1|1121216_1121762_-|phosphodiesterase	unknown	unknown	gnl|CDD|181869
NC_017297.1|WP_011987899.1|1104231_1104696_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_011987910.1|1117179_1117935_+|DUF4184-family-protein	gnl|CDD|379379	pfam13803, DUF4184, Domain of unknown function (DUF4184). This domain of unknown function contains several highly conserved histidines.	1.36483e-82
NC_017297.1|WP_011987908.1|1114038_1116198_+|YhgE/Pip-domain-containing-protein	gnl|CDD|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	1.83859e-115
NC_017297.1|WP_011987900.1|1105393_1105987_+|DUF1349-domain-containing-protein	gnl|CDD|377771	pfam07081, DUF1349, Protein of unknown function (DUF1349). This family consists of several hypothetical bacterial proteins but contains one sequence from Saccharomyces cerevisiae. Members of this family are typically around 200 residues in length. The function of this family is unknown.	2.85477e-80
NC_017297.1|WP_011948678.1|1120503_1120935_+|ferritin	gnl|CDD|153105	cd01046, Rubrerythrin_like, rubrerythrin-like, diiron-binding domain. Rubrerythrin-like domain, similar to rubrerythrin, a nonheme iron binding domain found in many air-sensitive bacteria and archaea, and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system. The rubrerythrin protein has two domains, a binuclear metal center located within a four-helix bundle of the rubrerythrin domain, and a rubredoxin domain. The Rubrerythrin-like domains in this CD are singular domains (no C-terminus rubredoxin domain) and are phylogenetically distinct from rubrerythrin domains of rubrerythrin-rubredoxin proteins.	2.70117e-55
NC_017297.1|WP_011987911.1|1118202_1120332_+|DNA-helicase-RecQ	gnl|CDD|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_017297.1|WP_011987901.1|1106050_1106251_+|DUF3788-family-protein	gnl|CDD|378906	pfam12663, DUF3788, Protein of unknown function (DUF3788). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 137 and 149 amino acids in length. This family may be distantly related to RelE proteins.	2.2975e-10
NC_017297.1|WP_011987904.1|1107687_1108542_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.79053e-09
NC_017297.1|WP_011987898.1|1102852_1103890_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378400	pfam10114, PocR, Sensory domain found in PocR. PocR, a ligand binding domain, has a novel variant of the PAS-like Fold. Evidence suggests that it binds small hydrocarbon derivatives such as 1,3-propanediol. In (Natural history of sensor domains in bacterial signaling systems by Aravind L, LM Iyer, Anantharaman V, from 'Sensory Mechanisms in Bacteria: Molecular Aspects of Signal Recognition.' Caister Academic Press. 2010) - see (http://de.scribd.com/doc/28576661/Bacterial-Signaling-Chapter).	1.57385e-56
NC_017297.1|WP_011987907.1|1111843_1114012_+|YhgE/Pip-domain-containing-protein	gnl|CDD|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	3.25813e-118
NC_017297.1|WP_003355968.1|1122398_1122782_+|response-regulator	gnl|CDD|381110	cd17562, REC_CheY4-like, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY4 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY4 and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.52388e-22
NC_017297.1|WP_011987903.1|1107318_1107642_+|TfoX/Sxy-family-protein	gnl|CDD|225612	COG3070, TfoX, Regulator of competence-specific genes [Transcription].	2.23699e-17
NC_017297.1|WP_011987913.1|1122896_1125371_+|DUF3298-domain-containing-protein	gnl|CDD|378702	pfam11738, DUF3298, Protein of unknown function (DUF3298). This family of bacterial protein C-terminal regions is highly conserved but the function is not known. Several members are annotated as being endo-1,4-beta-xylanase-like, but this could not be confirmed, and the structure can be defined as a heat-shock cognate 70kd protein 44kd ATPase.	5.10226e-16
NC_017297.1|WP_011987896.1|1099634_1101395_-|dihydroxyacetone-kinase-subunit-DhaK	gnl|CDD|237723	PRK14479, PRK14479, dihydroxyacetone kinase; Provisional.	0
NC_017297.1|WP_011987914.1|1125818_1126034_+|DUF2997-domain-containing-protein	gnl|CDD|314207	pfam11211, DUF2997, Protein of unknown function (DUF2997). This family of proteins has no known function.	5.06901e-14
NC_017297.1|WP_011987897.1|1101405_1102536_-|glycerol-dehydrogenase	gnl|CDD|181843	PRK09423, gldA, glycerol dehydrogenase; Provisional.	0
NC_017297.1|WP_011987902.1|1106372_1107218_+|aldo/keto-reductase	gnl|CDD|381383	cd19157, AKR_AKR5G1-3, AKR5G family of aldo-keto reductase (AKR). Bacillus subtilis glyoxal reductase (GR), uncharacterized oxidoreductase YtbE, and Bacillus aryabhattai aldo-keto reductase are founding members of aldo-keto reductase family 5 member G1-3 (AKR5G1-3), respectively. GR (YvgN, EC 1.1.1.283), also called methylglyoxal reductase, reduces glyoxal and methylglyoxal (2-oxopropanal). It is not involved in vitamin B6 biosynthesis.	1.0501e-169
NC_017297.1|WP_011948662.1|1104797_1105241_+|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	5.04422e-09
NC_017297.1|WP_011987912.1|1121216_1121762_-|phosphodiesterase	gnl|CDD|181869	PRK09453, PRK09453, phosphodiesterase; Provisional.	1.07904e-108
NC_017297.1|WP_011987899.1|1104231_1104696_+|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.71988e-22

Protein sequences

>NC_017297.1|WP_011987904.1|1107687_1108542_+|GNAT-family-N-acetyltransferase
MFIYDTLENIGIETLHETFLNAFSDYQVKMDLPLFKFQHMLQRRGYVSKVSIGAFNNETLVGFVLNGVRNWDGKLTAYDTGTGIIEAYRKQGITSNMLLNVRRLFQQMGVEQYLLEVIQSNTSALQLYKKQGFKILRDFECFHLDKNKYNPITTYKVEHVDMINPNDWRELTEFWDFVPSWQNSIDSINAVSDSFIYSIVRFDDNIVGYGVIDKKTGDIPQIAVNKNYRRKGIARSILTDLIKNTESYNINVINVDGRSKSMKDFLLKLGFECGVSQYEMILKL
>NC_017297.1|WP_011987903.1|1107318_1107642_+|TfoX/Sxy-family-protein
MASNIEFVEYVCDQISGAGDITYKKMFGDYGVYCNEKIIGLICDNQFFLKITKAGKDLLHEAIEAPAYKGAKPSFLIESLDNREYLAKIVSATYKELPMPKSKKTKK
>NC_017297.1|WP_011987902.1|1106372_1107218_+|aldo/keto-reductase
MQDIKSYTILNNGVKMPWLGFGTYKVENGDTVIQSVKEALKIGYGHIDTASYYGNEEGVGTAIKESRIPREDIFLVSKVWNSEQGYDKTLKSFEDSIKRLGTDYLDLYLIHWPQPLSKETWKALEKLYKEGRVKAIGVSNFLVNHLKWLLEDAEIMPMVNQVEFHPQLIQKDLIEFCSKNNIQLEAWSPLMRGKVFQIELLQELAQKYGKTISQIVLRWDLQMGVVTIPKSINPSRIKENADIFDFEISKEDMDKIQQLDKGLRVGSDPNKVYPCQSISNK
>NC_017297.1|WP_011987901.1|1106050_1106251_+|DUF3788-family-protein
MYGKKEIEQFESRIDEFSDYMKQIFNETKHYHDGKWLLIRIQDDKYINELIEMIKIKKKPKKKHIA
>NC_017297.1|WP_011987900.1|1105393_1105987_+|DUF1349-domain-containing-protein
MFRFNTKECEWFFEPKNYLIEEDKVEIITEPNTDFWQRTYYGFRNDNAHVLYVTTDEKYFSFTVKTDFNSTALFDQCGLAIYQNSENWAKACIEFHDNNTSWLGSVVTNHGYSDWATMDIGSSVKSMWYRLSRRGSDYCFENSFDGVNFKQMRIFHLFEGAKEINFGLLACSPSKNSFKATFTEMKITDCLWEEHKA
>NC_017297.1|WP_011948662.1|1104797_1105241_+|GNAT-family-N-acetyltransferase
MEIKIIEENKRSFLDLLLLADEQESMIDKYLNRGEMFALYDGDLKSICVVTNEEEGIYEIKNLATYEKYQGQGYGSRLIKFIFEYYKDNCKTMLVGTGDSPLTIPFYKHCGFKISHRIKNFFIDNYDHPIYESGVQLIDMVYLKKDF
>NC_017297.1|WP_011987899.1|1104231_1104696_+|GNAT-family-N-acetyltransferase
MNIRMYQLEDCREIVELFYNTVHSINSRDYNSAQLDVWAPKEIDIDSWYKSFSQHYSIVAEESDVIIGFGDLDETGYLDKLYVHKDYQGIGVATTIASELENYAQENHISIVTTNASITAKPFFKKRGYEVVKEQFVERNGQFLKNFIMKKVLG
>NC_017297.1|WP_011987898.1|1102852_1103890_-|helix-turn-helix-domain-containing-protein
MIKENLNLDKVIDFKKWIKLQESLALVTKAAIIVVDYKGNPVTEHSRCNRFCKAVRSNPDLVKYCHKCDSRGGLEAVRLNKPYIYLCHYNIVDIAIPIIIDGKYIGAIMAGQIKLSDNKDSDFLEQIVITPKNSTARHALKEFKEYYDEIPVLSLKEVQEIANMLFSLCNYLVEEALDKNLISEIYKKTVTPKSEIDSNTLTGYTMKNIENAKKEMSNVLLNSYVKENLSSDSLDISVSNTLKPAIEYIYNHKSENITAKKLAEVCHISPSYFSRLFAKETGKSFSSFISNLKVDWAKSLLEETDMPINEISDELGFNETGYFIKIFKKYESVTPFVYRKYCKKN
>NC_017297.1|WP_011987897.1|1101405_1102536_-|glycerol-dehydrogenase
MRKAFICPTKYVQGEDELLNLGYFVKSFGESALLIAHKDDIKRVKDKLDSTAKKFGITFVESSFCGECSREEVARLQEIAKNNKCACTIGLGGGKAIDTAKCVAKGNSLIIVPTIAATDAPTSHSAVLYTPDGSFDDYAYFWQSPTVILIDTTVIANAPTRFLVSGMGDALSTYFEARATSNSFSNVNAGLPCGVREGLCAPAKGTNTALTLAKACYKTLLEDGVKAKIASDCNLVTQALENIIETNILLSGLGFESAGLAAAHAIHDGLTILEGTHKYFHGEKVAFGTIAQLVLENAPKEEIDEVINFCLEIGLPVCLEDIGVDSITDEELMEVAKKSCIEEESIHSMPFKVTPEAVAAAIITADTLGKKYKSNK
>NC_017297.1|WP_011987896.1|1099634_1101395_-|dihydroxyacetone-kinase-subunit-DhaK
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASPSQIQIYKAIKATASEKGTLLIIKNYSGDMMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAGAAAELGFSLEKVKSIAQKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKVATADELAKKIVDSILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELLSKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDVETCDCHSKIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSHAGDGDFGMSVAKGFKQLKRDWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAEMMQAAVKGIQSTGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHETFQKGAAAAVKGAKMTEKIVARMGRAGTVGERSIGYPDAGAYGLGVIFTEISNSLK
>NC_017297.1|WP_011987907.1|1111843_1114012_+|YhgE/Pip-domain-containing-protein
MNRFKNIIKVYKRDIKSLNKNFIAIIIILGVCVLPSLYAWVNIKACWDPYENTSTVPIAVINNDKGTDFGGKELNVGNEMVKKLKSNDKIGWKFTNKKEADMGVVDGTYYASIEIPADFSADIVSVLSDNPKHPEIIYKVDTKENPVAAKITGMAKNTLINEITTTFITTVNKTVFSSINEIGRNLEKNKNEIIKLKESIISMNRNMDLILAGLESVNTNSKNLNGYLSVVRTTFPEITKGLENINSKSSNTNETINQTNNIFNNSLNNINVILKQAISTNNRVQSVLDNLIVLNNESSSNEANSSIANLIMDIDSANKNIDSMIEFLEKINNTKPNTEVSKFIVSLNNVKGALNEEKQKLIKIQEIASNSSKVNENSINELKRNISNTNKQIESVMNVFNSNTRQELSTIINNFKNSIQDASKLIKAGNGLNTQIENLLATSTKGADLSAKLSKELIDKLTEYKGIIGQLSKKLELVSNDDLIQIISILQNNPMLMSQTAAYPFNIKEEAVYDIPNYGSAMTPVYSVLALWVGTLILVSLLKTEVVDFEGSENITIRQKYFGKMLTFTTLAAMQGLVVAVGNKAILGVYTVSFPLMIAFSVVSSITFAIITYTLVAIFGKFGNALAIVFMIIQLAGSGGTYPIQVDPLIFRILQPFFPFTYSIGGFREAIGGPLVSSVILDFIMLILMGSIFVLIGFFLKSPLHHKVSKFDEDFKASGISE
>NC_017297.1|WP_011987908.1|1114038_1116198_+|YhgE/Pip-domain-containing-protein
MKKAFRIFSRDLKNIVKHPAAIIVVLGLSFIPSLYAWINIKACWDPYANTGNLPIAIVNRDEGMMLRGKYTNVGNGIVENLKGNKNMGWVFVDEWQANYGLNEGKYYALIEIPSNFTRGLASLKTTDPQKPNIIYRANEKSNAIATKITNAAKGSLAKQIQTNFVYTVNKEAFKLLNNTGGQLEKNKSKILGIKSTLELGNKSIGEVKNIIDDASKDSESLKQYFNDTKDKLPLITDQINNLQKATEASKNLVNETERDLNGIAKNINNDMIYRESTNSKINSILTNLKEYNNVSNNSEMIKLVDEASKLCDSINSNIDGTIKSLEVVNILKPNKIIEELISSLKNLQEKVNGEKNKLAELKNKISTSNNNKQNINQVVESILLLNDEINKNMRNTSNIFYNQTTMIIENTAKGLNNRLDTANDILDTTKLVIPQLKALGDFGVGTSDAALKDGKKINNKLAEFKKTINKLEEKTSSLTEDNLDKIINLTQKNPEQMASFISSPINIKEEEIYNTGIFGVGLTPFYTVLAIWVGVLLMSSLISVEAEEFEGEKKLTHLQVYFGKLLLFLSIAIIQGIIVTLGDVFILGIEPASMGLLMVFTIVTAITFTFIIYTLVSIFGNLGKAIAVVIMVFQIAGAGGIYPIQTNPKIFGVLQPLWPFTYAIAGFREAIAGPVRAAVIKNLGALFIFSIGSLLLVVLKKPLHKVTEYMNDKFIETGL
>NC_017297.1|WP_011987909.1|1116671_1116974_-|hypothetical-protein
MEKKPSVKSSANLLAIVSLIMSIIVILPILNWLFKITPWQKLEGLPLFFGLLISPFGFLLGILSIKIQSNKLGKIGVIINTLLFLLPFIYMTLGVLIFGP
>NC_017297.1|WP_011987910.1|1117179_1117935_+|DUF4184-family-protein
MPFTFSHPAIVLPLEKKWNKYFSFTALILGSMSPDFEYFIRFKPMATIGHGLIGFFLYNLPLCFILAYLFHKIIKKPLIAHMPKPIDSWYYNTALKPWRINSLTQVLVFSYSAIIGMITHVLWDSFTHKGGKFVILFEGLRKNIEILNYDIPVYKTLQHGSTLLGVIFIILYIYSKRNKHINWKRINRIPAINNKEKVSYFTTIFCTGLIVLFVYIFLLNVSFSIKNVGSFVVTFINGLFIGTIITSIKCR
>NC_017297.1|WP_011987911.1|1118202_1120332_+|DNA-helicase-RecQ
MLESAKNLLKKHFGYNEFRKAQEKVIESILKKEDTVAIMPTGAGKSICYQIPALIFEGVTVVISPLISLMKDQVDSLKEVGIEATYINSSLNNLEIEERIFNAREGLYKLIYIAPERLESDNFVRSLNNLNIALVAVDEAHCVSQWGHDFRPSYTKISNFIRKLSKRPIVTAFTATATETVRRDILKSLELQNPKVFVTGFDRENLSFSVIKGEDKEKFIFDYLENNIGKVGIIYTSTRKEAESLYNKINKKGYTVGVYHAGLSDEERKKTQEDFSFDNIEIIVATNAFGMGIDKSNVRFVIHHNIPKNMEAYYQEAGRAGRDGEESECILLFSPNDIRLQKYFIDESFLSPERKNNEYNKLRAMVDYCYTSKCLRSYILEYFGEDALEEKCNNCSTCNDNREEKDITLEAQKIFSCVYRMKERFGVNMVADVLRGSKNKKLLSLDLDGLSTYGIMEEFTQKDIVALMNKLIADDYMVTTDDKFPVVRLRSKSHDVLKGKEIVSIKVSKIEKKVKADNELFEILKQLRKAISQEESVPPFMIFPDATLKELSEYMPTKEEDLLKIKGIGERKAEVYGERFIEAITEYMNEKGIDINNMDNYESTKSNKESKIKTHVLSYNLYKEGKTIKEISEERNLKAITIQEHLFKCLSEGMEVDLDNFIKKDYEKLILDTIKKVGGTKLKPVKDELPLEVDYMCIKSVWYKYKDII
>NC_017297.1|WP_011948678.1|1120503_1120935_+|ferritin
MDELDIINENQLGIAANNEKIKTDLEGQFRAETGEVGLYIAMARVAQRQGFPEIAEVLKVIATEEAEHAARYAELNGKVSDCTKENLQKMLQGEIGSNKMKKSLAVKAKEENIDEVHDFIDEASRDEARHAKMLKGLLDRYFG
>NC_017297.1|WP_011987912.1|1121216_1121762_-|phosphodiesterase
MKLFFMSDIHGSAYYLEKALHIFEKEKADYLIILGDELYHGARNPLPKGYDPKKVTEILNSYKDKIIAVRGNCESEVDQMVLNYPIMSDYSIVLYNGKRLFLTHGHIFNKDNMPNISDGDALIYGHTHIPLAEKINNIFVINPGSITFPKENTPHCYGILSDNLFKIKTLEGNTFKEISLI
>NC_017297.1|WP_003355968.1|1122398_1122782_+|response-regulator
MSSSQKNILVIDDSASIRSFVRNILEKANYKVYEACDGEEGIEVYKKCGNIDLVMTDIYMPKKSGLEVVVELQNKYKGTQIIVFSDGGKENFTNDSGVCEALGAAYFIRKDLIKDKLLDLVNIIFSK
>NC_017297.1|WP_011987913.1|1122896_1125371_+|DUF3298-domain-containing-protein
MIERNLFNIINKYLPMGSQIIVEEDNNNEPLIIKADLNGYGLGEIIIAYRWQEENYIMVLERYCNQWSVIDNIRGKGYDISYLKVAPITDNAMDNLIIGWRRGAIWSELDILQWTPYGFKRVIDEGIYYSKIEVENMKSVKAMNDKNEIALWLHDTAEAYKVEIYRWSLGKLVKAEDVYPYYFKKVIDFYKTKLQEEPDLPVYWYYLADAQIKGEMYEDALKSIDKALELPKAYPSKKELIKLRDYILSHKKCKNINLYLAPMNTIKGVRWGYINEKGEFLIKPLYNLALEFQCNGLAVVEIDNLYGIIDENQDYIVKHKYGFISDFSEGRAIVIDNERFNIINEEGEELIAKTENYSYIGNFKEGRAQYGVIDSNKGYLYGYLDREGKVIIPAQYEYGNDFYKGKAVVRIKENEYALININGEILNKYEYASVGNLREGLLSFKKDMGEKYGFIDEDGNVVIKLQFTYAQDFSEGRSVVNVSGNIMNNYGVIDKEGNYIITPKYNDIILLGENRVAVGVAIDKTSPFIGSKYAIADTEGNILTDFIYYEVSNYKSGIASAYDDKNTFFIDKEGNKIENLPIVEGSGTLTVENELIKAYVDYKISYFDKEGNLIWEENSVISLNNQYKVIEGKYKPNKDYLVYYPKVQGMVDKALEDGVNNRLKILSEVKPIEENVQLEYNYLGDFKIEFFNKNLLELELDGYNFHFGAAHGMPSKIYTKIDLTTGEFYELKDLFKEDSDYVKALSDIIGEQIKNNPEYSYIFPDTYNGIKEDQPFYVSQDTLYIYFYPYEIAPYAAGFPTFKIPYKDIIDIINEAGAFWISFN
>NC_017297.1|WP_011987914.1|1125818_1126034_+|DUF2997-domain-containing-protein
MTKQIKLRIYPDGIVQAEVEGVKGKKCTNYISIIENLLEAKVADSEYTPEYYEEEIVESYEEENITLKEGR

Crispr_ID: NC_017297_3

• CRISPR_ID: NC_017297_3
• CRISPR_location: 1903423-1903640
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas3

Consensus repeat of NC_017297_3

Consensus_repeat	Method
ATAATAATATAAAAGATATATCT	CRISPRCasFinder

spacers of NC_017297_3

>3.1|1903446|43|NC_017297|CRISPRCasFinder
CCTATTAATAATATGGAAAAACTAAAGGATATAAATTTATCTA
>3.2|1903512|40|NC_017297|CRISPRCasFinder
TATTTAAAGGATTTAAACTTACATCATTTAGATTTAAGAG
>3.3|1903575|43|NC_017297|CRISPRCasFinder
GTCTTAAAAGATAAAACATCCTTGCAACATTTGTATTTAGCTA

CRISPR arrays and Neighbor proteins around NC_017297_3

CRISPR arrays

The CRISPR arrays of NC_017297_3

>merge|NC_017297|3|1903423-1903640|CRISPRCasFinder
ATAATAATATAGAAGATATATCTCCTATTAATAATATGGAAAAACTAAAGGATATAAATTTATCTAAAAATAAAGTAAAAGACATATCTTATTTAAAGGATTTAAACTTACATCATTTAGATTTAAGAGATAATAAAATAGAAAATATAGAAGTCTTAAAAGATAAAACATCCTTGCAACATTTGTATTTAGCTAATAATAGTATTAAGGATTTTTTA

>NC_017297|3|3|1903423-1903640|CRISPRCasFinder
ATAATAATATAGAAGATATATCT	CCTATTAATAATATGGAAAAACTAAAGGATATAAATTTATCTA
AAAATAAAGTAAAAGACATATCT	TATTTAAAGGATTTAAACTTACATCATTTAGATTTAAGAG
ATAATAAAATAGAAAATATAGAA	GTCTTAAAAGATAAAACATCCTTGCAACATTTGTATTTAGCTA
ATAATAGTATTAAGGATTTTTTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012099775.1|1892466_1893360_-|chemotaxis-protein-CheV	unknown	unknown	gnl|CDD|223905
NC_017297.1|WP_041173147.1|1890382_1890841_+|YbaK/EbsC-family-protein	unknown	unknown	gnl|CDD|239825
NC_017297.1|WP_012099771.1|1886196_1888200_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|223910
NC_017297.1|WP_012099772.1|1888480_1890061_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|237894
NC_017297.1|WP_012099774.1|1891411_1892266_+|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|225131
NC_017297.1|WP_012099785.1|1910095_1910557_+|chemotaxis-protein-CheX	unknown	unknown	gnl|CDD|224324
NC_017297.1|WP_011986372.1|1908998_1909181_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012099784.1|1909241_1910096_+|response-regulator	unknown	unknown	gnl|CDD|381097
NC_017297.1|WP_012099777.1|1895316_1896153_+|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|225543
NC_017297.1|WP_012099779.1|1896331_1897777_+|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl|CDD|223587
NC_017297.1|WP_012099787.1|1913500_1913830_-|HesB-like-protein	unknown	unknown	gnl|CDD|188182
NC_017297.1|WP_003403080.1|1912836_1913040_+|alpha/beta-type-small-acid-soluble-spore-protein	unknown	unknown	gnl|CDD|365990
NC_017297.1|WP_012099780.1|1897933_1902391_+|DUF5050-domain-containing-protein	unknown	unknown	gnl|CDD|379846
NC_017297.1|WP_012099776.1|1893728_1894994_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NC_017297.1|WP_012099770.1|1885618_1885828_+|cold-shock-domain-containing-protein	unknown	unknown	gnl|CDD|278729
NC_017297.1|WP_077272268.1|1914347_1914560_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012099789.1|1916047_1916521_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_003358834.1|1916818_1917424_+|transcriptional-repressor-LexA	unknown	unknown	gnl|CDD|234688
NC_017297.1|WP_012099786.1|1910739_1912098_-|YjiH-family-protein	unknown	unknown	gnl|CDD|225851
NC_017297.1|WP_003363259.1|1913100_1913301_+|alpha/beta-type-small-acid-soluble-spore-protein	unknown	unknown	gnl|CDD|365990

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012099779.1|1896331_1897777_+|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	1.9e-15	51.5	4.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012099775.1|1892466_1893360_-|chemotaxis-protein-CheV	gnl|CDD|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	2.68688e-31
NC_017297.1|WP_041173147.1|1890382_1890841_+|YbaK/EbsC-family-protein	gnl|CDD|239825	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS). While ProX and ProRS-INS hydrolyze misacylated Ala-tRNA(Pro), the E. coli YbaK hydrolyzes misacylated Cys-tRNA(Pro). A few CD members are N-terminal, YbaK-ProX-like domains of an uncharacterized protein with a C-terminal, predicted Fe-S protein domain.	1.01984e-75
NC_017297.1|WP_012099771.1|1886196_1888200_+|methyl-accepting-chemotaxis-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.11743e-53
NC_017297.1|WP_012099772.1|1888480_1890061_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NC_017297.1|WP_012099774.1|1891411_1892266_+|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	7.51632e-74
NC_017297.1|WP_012099785.1|1910095_1910557_+|chemotaxis-protein-CheX	gnl|CDD|224324	COG1406, COG1406, Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion].	2.63863e-41
NC_017297.1|WP_012099787.1|1913500_1913830_-|HesB-like-protein	gnl|CDD|188182	TIGR01911, conserved_protein, HesB-like selenoprotein. This model represents a family of small proteins related to HesB and its close homologs, which are likely to be invovlved in iron-sulfur cluster assembly (See TIGR00049 and pfam01521). Several members are selenoproteins, with a TGA codon and Sec residue that aligns to the conserved Cys of the HesB domain. A variable Cys/Ser/Gly-rich C-terminal region is not included in the seed alignment and model. [Unknown function, General].	1.13718e-22
NC_017297.1|WP_012099784.1|1909241_1910096_+|response-regulator	gnl|CDD|381097	cd17542, REC_CheY, phosphoacceptor receiver (REC) domain of chemotaxis protein CheY. The chemotaxis response regulator CheY contains a stand-alone REC domain. Chemotaxis is a behavior known for motile bacteria that directs their movement in response to chemical gradients. CheY is involved in transmitting sensory signals from chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY, which causes counterclockwise rotation of the flagella, resulting in smooth swimming. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.48041e-52
NC_017297.1|WP_012099777.1|1895316_1896153_+|S1-RNA-binding-domain-containing-protein	gnl|CDD|225543	COG2996, COG2996, Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only].	2.33735e-81
NC_017297.1|WP_012099779.1|1896331_1897777_+|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	8.08404e-151
NC_017297.1|WP_003403080.1|1912836_1913040_+|alpha/beta-type-small-acid-soluble-spore-protein	gnl|CDD|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	1.88902e-25
NC_017297.1|WP_012099780.1|1897933_1902391_+|DUF5050-domain-containing-protein	gnl|CDD|379846	pfam16472, DUF5050, Domain of unknown function (DUF5050).	3.45967e-50
NC_017297.1|WP_012099776.1|1893728_1894994_+|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.91219e-113
NC_017297.1|WP_012099770.1|1885618_1885828_+|cold-shock-domain-containing-protein	gnl|CDD|278729	pfam00313, CSD, 'Cold-shock' DNA-binding domain.	6.08098e-21
NC_017297.1|WP_003358834.1|1916818_1917424_+|transcriptional-repressor-LexA	gnl|CDD|234688	PRK00215, PRK00215, transcriptional repressor LexA.	1.0926e-108
NC_017297.1|WP_012099786.1|1910739_1912098_-|YjiH-family-protein	gnl|CDD|225851	COG3314, COG3314, Uncharacterized protein conserved in bacteria [Function unknown].	1.9313e-118
NC_017297.1|WP_003363259.1|1913100_1913301_+|alpha/beta-type-small-acid-soluble-spore-protein	gnl|CDD|365990	pfam00269, SASP, Small, acid-soluble spore proteins, alpha/beta type.	6.55884e-25

Protein sequences

>NC_017297.1|WP_012099780.1|1897933_1902391_+|DUF5050-domain-containing-protein
MIRGVFAIFSKKFVAKLLLYSSIAIIPMFNHNYVQAASSKQYETKYNVSLDKVWKIRFSREVDKATLNPENIKILDNQGKEMPINLSLDVDKHYVKIALKSGTYNGVHYSGKYEKDKKYSLIVKEGLMSEPSKNKKSKNLAYETMMDFNTIGDNEYPGLPIEDGLIVIGDKAYSVGYLSKHSSIANEITSNGNYYIAYISKEYGEKIKQVLGNNTTKGNQERANKILYYAPNGNQYEYEWNEAFGEYKIVLPKAYVDVTPGVINGVVNLAVKQVKAVPGAKYFKLAHSNTIKPIGESISYSMTYPTEKLTILSADETPLATALVDVYLPKTGYVSLSSVNETLGNTAGNISNNGSAAMDLDFYVYYVNSADKNSLYRKTLTGRMDTQISLDKAQYINVIGDWIYYSNYNDNGKIYKMKKDGTKKQILCDDTATYITVSGGVVYYANQSDKGRLYKINTDGTIDGGTSNRDPAGKVHGMPVMDDYGNYNKATDQANFINVVGDWIYYSNFSDGHKIYTVNKDGNIRRKVNDEWADGIQIVGAWAYYCSGSGAISKVRVDGTGSVIPLRGTTRKVDKGYHLNIVDGWLYYSNAEDGGKLYRIKEDGSGEKKKLADLATDYINIVGDTMYLISAGKTYTLPLNTDGTIKPTLVTKDNNGNTVVDVKDLNITVAYEDANKTIGELEAKYLPQKVAVFMKDDTVQQLPVDWDIKNRKYNGQGIYTYTGTVLGHGKQIKCTLTIPSEMLNATSIIEVYNNGPKNGSIMIKERSFGPSKQDQELKEKLKLAKRVEIGDVIKVYDNPNSEKPLGNIKVDANNANGPLVKSLDLDMYGRSFWITITRKNKAESKPTEVRQLGAAVLSGDVLDEDGEALGVDGRDFTVKGWNNPSIRDDGFISDTTEIAAQGTKSIYVIPGTGKLNMENQGVIPAGITSANYWNGGNARALLTNYDLLTNDSLKNKLKEGNYSIYVVVGYDGKAEEDVNGFGSPLVIGKTASIPKAMKATEEKIPKAPSVTKQYVKAGDTVKISGVTKEDEIYLAPEGASYIAKDITNKPYKSHDNLFFEDQSKSKEEREKEYEKSGKPSIEDGYQCKLVDGKIPQGVRSGKYKVYMVNAIGSSSPASGEIVIDNEDPVVRLDSAKQEDVIKTVTQNGTTTQETTGQKFKVNFAAFDNSFDNSIKEGITVSMARLDSPKSAIKAQEIKDKGNKTFEVIINDPHANLNDYAIYAEDKAGNIGQVNLKVQDPPVNINNISLAIRTSNEGVDLVKSRLVGRTKYMTKDLTRVSDNYEVTVDGVKYVLQEEALRNLGASPSIDAFMNALMQAKQWDIANNKPMEDKPKLSSKVSIYKVNDIIYIEGNDNTPIQIEDRTKIDADTAIVSNMIGLNSNENSTGENSKNQQYIINVTGTAQKNGKLKVCLAGKCFDIDILSTDDATKIARKIKDVINDNTILDSYQYPGTNVESSGSEVKLTRKSPGAVVPTFTVEYFNYDN
>NC_017297.1|WP_012099779.1|1896331_1897777_+|DEAD/DEAH-box-helicase
MNKLTFENYKLSDEILKSLGKLGYKNPSEVQKQVIPLILKDKDIIVKSETGSGKTAAFSIPVCEKLELEEKDPQVLVLTPTRELALQIKEEISSIALYKRLRCTAIFGKQPMSLQKRELKQRVHLVVGTPGRTLDHIERENLDLKKIKYFVLDEADEMLNMGFIDQVEAVIKRLPKNRVTMLFSATIPEKIENLCKKYMNNPQNININPENITTDTINQCYYEVEDKDKFSLLQKIIYKEVVDNSIIFCNTREKVDEVLKNMKKKGLNAVGLHGGMEQKDRLETMKKFKEGEFQFLVCTDVAARGIHIENISHVINYEMPYEKESYVHRIGRTGRAGKEGVAITFIEPNKVRFLRDIEDYIEKEIPKRKEPSLEEVDKGKKIFEENIKNRIKTKVPKNNKKQKDITKIYISAGRKKKIRPGDIVGAITSIEGINVDNIGIIDIQDNHSYVDILEGKGDIVLKASEDMKIKGKKVRIQRAVK
>NC_017297.1|WP_012099777.1|1895316_1896153_+|S1-RNA-binding-domain-containing-protein
MIKLGEIQKLEIIREAPMGVYLNSKEDKSENDILLPGKQVPKDAKIGDEVEVFVYRDSEDRMIATINRPKITIGEIAPLKVIEKTKMGAFLDWGLERDLFLPFKEQTYGIQEGMECLVYLYIDKSDRLCASMNVYRVLSTESPYKEDDEVKGFIYDIKREIGAFVAVDNEYHGLIPKNELYGKFRYGDIVEARVTKVKEDGKLDLSIRKKAYKQMDEDVDTILEKLNSNGGKLYLNDNSDPRAIKELLSMSKNAFKRAVGRLLKEGKIEFIEKGIKLK
>NC_017297.1|WP_012099776.1|1893728_1894994_+|DEAD/DEAH-box-helicase
MNNSFDTLNLNPKLVQGLKKLNINIPTEIQAEAIPLAMENKDIIGQSETGTGKTLAYLLPIFEKITTEKREMQAIILAPTHELAMQINNEIKNISSNSNMDVKSMAIIGEANIKRQIEKLKEKPHIIVGSPGRILELIKKKKITAHTVKTIVIDEGDKLLDKNNLKVVKEVIKTTLRERQLMLFSATITESTLNIAKDLMKDSEVVKVKEKNTVNENIKHLYITGEHRERIEILRKLIAATNPKRAIVFINRNEEIELTTLKLQYHKIKAYGIYGAAEKEQRKKALEDFRSGKVQILVSSDLSARGLDVKDVTHIFNLDLPENPKEYLHRVGRTGRASKEGIAISIITEKEKALIRKYEKEFNINIEEKKIYKGTLISSKGERSSQPKSKNKSTSAHKDNNKKKRSSSINKSKNNHKKKKY
>NC_017297.1|WP_012099775.1|1892466_1893360_-|chemotaxis-protein-CheV
METNILLESGTGEVEIIEFLVNNKHYAINVIKVKEVIEVDNVTKVPQSDPAIEGLILCREKIFPLIDLSYILGQKNTSKKRFKTIICEFNRVSVAFKIDEIVAVHRIGWDKILKPDDIAANPLVIGNILLKDKIILLLDFEKIVTDINPSTGISEERIVNVDYKDRSHIKVFLADDSSLIRKLLKDTLTKAGFKKLTIFDDGKQVLDKLLELVEKKGEDFTEDVQILITDIEMPQMDGHTLTRKVKEHPILKRLPVIIFSSLITKDLKHKGTSVGADEQLSKPDIGELVNIIDNYIE
>NC_017297.1|WP_012099774.1|1891411_1892266_+|4Fe-4S-dicluster-domain-containing-protein
MKMISKNEIAKLKGEGFLAQKQEGYFSVRILSRAGNFTSKQIIKLAEIADNYGKGYLGVTTRLATEIPWIRYEDIEAVKKEIVSSGMAHGGTGKRVRPLVSCKGTVCVHGLYDTQKLCGELHDKYFGYELPSKFKITLVGCPNNCAKASINDIGIMGQAYVEFDEEKCKTCGICTKSCRQKAVTVENKKIVYKKDLCVNCGKCATVCPFEAMTIKEQGLQVYLGGRFGREYRIGNRLKGLYKEEEIPALVQKIFDVYSEMGNPGERLAKMIERVGFDKVEEAIL
>NC_017297.1|WP_041173147.1|1890382_1890841_+|YbaK/EbsC-family-protein
MSLEGVKKQFTDENLNLKILEFDKSTATVELAAKALGVEPGQIAKTLAFHVKGENMLIVAKGDARIDNKKFKAYFNGKGKMMAPEVVLEVTGHAIGGVCPFGLENPINIYLDQSLKEFEKVYPAAGNANTAVEVTLDELEGITKGLWIDVCK
>NC_017297.1|WP_012099772.1|1888480_1890061_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MITVTNLSLRYGDKKLFEDVNLKFTPGNCYGVIGANGAGKSTFLKILSGEIEANTGDVSIQPGVRMSILKQDHFKYDEFPVLETVIMGNERLYQIMKEKDAIYAKTPFTDEDGIKASELEGEFADLNGWEAEAEASSLLQGLGIGTELHEKNMKDLSGSEKVKVLLAQALFGNPGVLILDEPTNHLDIKSVNWLEEFLINFEGTVIVVSHDRHFLNKVCTHMADVDFGKIKLYVGNYDFWYESSQLALQMAKDQNKKKEEKIKELQEFIARFSANASKSKQATSRKKLLDKIDLDNIQPSSRKYPYIAFKPEREVGNDILRVEGLTKTIDGTKVLDNISFIIGKDDKIAFVGDELSITTLFKIISGELKPDSGEYKWGITITNAYFPKDNSEYFNDVDLNLVDWLRQYSEEKSESYLRGFLGRMLFSGEEALKEVKVLSGGEKVRCMLSKMMLNNANVIILDQPTNHLDLESITALNNGLMDYKSNILFTSHDHQFIQTIANRIIEVSEAKFVDKKVTYDEYLESK
>NC_017297.1|WP_012099771.1|1886196_1888200_+|methyl-accepting-chemotaxis-protein
MKFKTMKGKMLTYFLSLFLIICIAISFMAYFMSKRMIERKASSLMSEVSRQAVQNIEARLNGTLDSIETVANMPTIKDPKLGWDKKKTILDEEIKLHGHVKMGIVGKDGQSIQTDGTTVNIKDRNYFKETMEGKRTISEPIVSKVDGKVVIIYTVPIKNGNTIMGALTAVREGNDISNISNSIKVGESGGAYLIDSTGTVIAHKNKESVIKRENSIKDAQSNEELKPIAAIEKSMIEGKEGIGQYKYKGAEKYISYSPMKSTGWSLAIYAPKNEILKEVSEITRNIIIVSILGIGIALVCIWFISTQISNNLISMRDSLNIVATGDLTTNVDSKIEKEKDEIGHMARALSKTVLSIGNMINSLKGSSFNIDDKANNLAAISEEFTATTENVSTAIQEVATGATNQAQALTEIVSMLNDFSDKINSTVNNIEEIDGMSKEIDEKANVSNKDMKELLNSIENLTKVFENFETKIWTMESNVQKINEITNLINDIAEKTNLLALNAAIEAARAGESGKGFAVVAEEIRKLAEMSRKSSEDIYTIVNGVLEDTKDMVKSSNEVNEKLNGQRSTADEAMNSFMEISKSVTNMIPKIRNINNSANIIEKNKNEILNKSETIASISQEISASAEEISASSEEMSASSEEVANTAQSLNDMTQDMLNEMNKFKTE
>NC_017297.1|WP_012099770.1|1885618_1885828_+|cold-shock-domain-containing-protein
MSMHTGTVKWFDNERGYGFIAGNNGKDVYVHYMQIKEKTHNKDLHEGEEVLFDIVEKEKGPIAINVQKL
>NC_017297.1|WP_011986372.1|1908998_1909181_+|hypothetical-protein
MYSIKYYLRYIKSKVLWETIYDKFFIQETIKKFFINLKKLIILMKKIHINCLNFKKNILK
>NC_017297.1|WP_012099784.1|1909241_1910096_+|response-regulator
MKDTKVVIVDDSPFSISIIKDILEENGLTVVGEAGNLEEVINVVKDKKPDIVTMDMTLPGTDGIECIKAINKINKNVKVIVISSMMDEEIVKKANKNKVCGYIQKPIDPEELIETIEKVVMKEELFLQLENDYFQIFKESFKDALNKFTKTTAEFSEDTKCTISETSRGMVVVIGIIGNFSGRMILDLSQETANSMVNFMLKREPKDMNEVLNVIGEFSNIVAGNACSMLNRKSKVFGLRIAPPSIFYGKSLNISQSLIESLSVESNTEFGQIYMNVGFKRGES
>NC_017297.1|WP_012099785.1|1910095_1910557_+|chemotaxis-protein-CheX
MDAKYINPFIDSFYNVLPQIGFSNVTREDVAIKNNVESLGILINLGIVGDIKGNIVYNIQGENGKKIASKMMMGLPVEELNEMAQSALSELSNMLTANASINFSNIGVNVNISTPTLMYGQDIKIKLNTDKILNIKIVADDIPIDVNIAFEKI
>NC_017297.1|WP_012099786.1|1910739_1912098_-|YjiH-family-protein
METQKNNKYSFSELFKFICPSLIGFILFIIPISYDGEITIPIAVLSKIVLAGLGSILPQLMGIIICITFICTAITKIFKPKAILENKFFNNLFNVSPVWVLARVLGFIFIISTFFKIGPEWIWSENTGGLLLYDLLPILFSVFIFAGMLLPLLLDFGLLEFVGALLTKVMRPIFNLPGRSSIDCMASWLGDGTIGVLLTSKQYEEGYYSEREAAIIGTTFSAVSITFSLVVISQVKLAHMFVPFYLTVCLSGIIAAILIPRIPPLSRKPDTYLNGGESKNSEALPEGYTPFTWGLEKAVAKAGSNDDPLNFIRQGLQNVLDMLLGVTPVVMAMGTSALILAEYTPLFKWLGLPFIPLLNLLKIPEAALASQTIVVGFADMFLPSVIAATIQSEMTRFIIACLSVTQLIYMSEVGGLLLGSKIPVSLKDLVIIFLERTLVTLPIITLVAHILF
>NC_017297.1|WP_003403080.1|1912836_1913040_+|alpha/beta-type-small-acid-soluble-spore-protein
MPSNKNSNNLVVPEAQQGLNQLKMEVANEVGIANYDSMDKGNLTSRQNGYVGGNMVKKMVEAYERNL
>NC_017297.1|WP_003363259.1|1913100_1913301_+|alpha/beta-type-small-acid-soluble-spore-protein
MANRNSNNLVVPEAKHGLNQLKMEVANEVGIANYDAVDKGNLTSRQNGYVGGNMVRKMVEAYERNL
>NC_017297.1|WP_012099787.1|1913500_1913830_-|HesB-like-protein
MTPVNMSDLAYKEFKNFIKENNVNSNIFRIFLAGNGUGGPVFNIVLDEQTSEDLLSPIGELSFLVHKDLFSEFGGFIIKCAEENGKGSFTIDPIIQSENISCSTCSSCS
>NC_017297.1|WP_077272268.1|1914347_1914560_-|hypothetical-protein
MKHAKLLIIVYLRRYSLASDLYYGRNRILKLPSLSSLIAYQLIMNINYLAMHNSIFIHSNLSTACVKKWY
>NC_017297.1|WP_012099789.1|1916047_1916521_-|hypothetical-protein
MNRETCIFNYTKKCTDCGECEICDLDQNKKCDNCGECLQREGIDTQAIKIDEIKEDKNFVDKEDLKKVLKEDEKELESLKEFEEDLENEILQETELLKDYDENFKEQGLYAIENVEGVEIEYIEDVDGLSELMEDESRLKKVAYEEFPGLIKIRENK
>NC_017297.1|WP_003358834.1|1916818_1917424_+|transcriptional-repressor-LexA
MNKSRIDKQNEVYNFIKLQIKEKGYPPSVREICKAVGLSSTSSVHFHLKRLEKEGLIKRDSSKTRAIEIVDPTSKKEVINVPIVGTITAGNPILAIENIEDVFPLPIDYVKNTKDLFMLKVSGESMIEAGILDGDLAIIEKTDSANNGDIVVALIDNEATLKRFFKESSYIRLQPENKSMKPIILENCKVLGRLVGIYRKY

Crispr_ID: NC_017297_4

• CRISPR_ID: NC_017297_4
• CRISPR_location: 2351786-2351882
• CRISPR_type: TypeIII-C
• Repeat_type: III-B
• Spacer_info: 1 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11

Consensus repeat of NC_017297_4

Consensus_repeat	Method
ATTTAAATACATCTTATGTTACTGTTCAAC	CRISPRCasFinder

spacers of NC_017297_4

>4.1|2351816|36|NC_017297|CRISPRCasFinder
ATTGATTTACGAAGGAGTAAAAGGAACTAATCACGC

CRISPR arrays and Neighbor proteins around NC_017297_4

CRISPR arrays

The CRISPR arrays of NC_017297_4

>merge|NC_017297|4|2351786-2351882|CRISPRCasFinder
GCTTAAATACATCCTATGTTAATGTTGAATATTGATTTACGAAGGAGTAAAAGGAACTAATCACGCATTTAAATACATCCTATGTTAATGTTCAATC

>NC_017297|4|4|2351786-2351882|CRISPRCasFinder
GCTTAAATACATCCTATGTTAATGTTGAAT	ATTGATTTACGAAGGAGTAAAAGGAACTAATCACGC
ATTTAAATACATCCTATGTTAATGTTCAATC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl|CDD|379915
NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein	unknown	unknown	unknown
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	unknown	unknown	gnl|CDD|236545
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	unknown	unknown	gnl|CDD|183481
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	unknown	unknown	gnl|CDD|340904
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl|CDD|236502
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|376899
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	unknown	unknown	gnl|CDD|379767
NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl|CDD|238129
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99905

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein	gnl|CDD|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000168002
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	gnl|CDD|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.72129e-11
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	gnl|CDD|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.79844e-156
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00629e-119
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.6734e-12
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.09381e-97
NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.49135e-104
NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC	gnl|CDD|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease	gnl|CDD|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.00217594
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	gnl|CDD|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.38777e-26
NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	1.55586e-29
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	gnl|CDD|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	7.73943e-38
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	gnl|CDD|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	8.26522e-29

Protein sequences

>NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein
MDKFRNMKKSHIALLAVMYIVLMGSLPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGNSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEDLTPCSVCNP
>NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNSYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNNLASVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPELLILVIVFITVEYILKRNFNKKISEQY
>NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYDKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPINFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKNRS
>NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYANK
>NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDEKVKSVAKYLEIEKVLDKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKATILMVTHDAFAASYAHRILFIKDGKIFNELVRGKDTRKEFFNKIIEVTSLLGGDDNNVF
>NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease
MIIMYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIKSSGGSYVSRLMEFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVTETSIVGVISLIAGLIIGMGVSQGLSVFALKLFEVSINEYRFAVSTRAISKTILYFGIMFLLVMIFNIFVISKYKIIDLLISGRKNENIKFKNTFIYLLSFVLCVVLLGFAYKSILKTGLKLREPMFKPSIAFVIVGTVLFFFSLAGVILYVVNKNKKIYFKGLNMFVVKQINSKVNTNFLSMSLICLMLFITILVLSTGISFKNGLEEGVRIRAPFDASIIISNNSKKDNLEDVLDKINFKKSKNEKYATCNEYISGVKLESLLSITDKDYKDAEVFFVKISDYNKILKLKGKKEINLNKDEILVMSTNNAVVKQANEKLKNSKKFNIKGKEYLVKNDTIIEENLATYLLADNVFTIVISDEFLYDYNKIVYSILNVTYSDKNREENNKKYSEINKNFVGGKYKSLNISYMGAFSKDDIYSGSKGGTTSILFVGIYLGLVFLITSMAVLALQQLSEASDSIERYKALKRIGASSKMIEKTIFLQTLIYFALPMILALVHSMIGIKVISDYIEVFTKIDISFSALITSLIFIVVYAGYFYTTYIGYKNIVESNI
>NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase
MLKFAYNTNGLRNMPLEEAIKQISNHNYDGIEISLHKQHFHPLNINIEEVKKIKSTVKSSGLVLSDIATGCDDILSDDKFEPSIICKDSIGRKKRIELLIKTAGFAEYLGVDVINFATGFKSDKVSNSEAYDYLKQGINYLLVKCPNTTFALEPEPDMFIEKTEQAIKLINEINTPRLMLNLDIGHVYCCEENPILSIRKSIPYARHIHIEDIKNRVHYHQIPGTGDIDFNTIFKDLIKYNYQHYISVELYHHADDWNNALDKSIKYLKQIEHHIRIVDSMELVQ
>NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPIKHIMSYPTDIRKRVENLPQYKDVIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSRGMVHFISII
>NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILRKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKIIREITEKDRKYYYKNYEFDIDDYKE
>NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSIEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGEFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIHDREKYLKNCAVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDKLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein
MKNKLKILIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANKYSAGFSLQTSKEPYEITVNYKANENLGEENYNKFWSDKKADKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKNLEQKYGNLKDLSKDNDSLKKFLNN
>NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein
MIYINLNTSYVKVQRTPVTIDGKEYTNLNTSYVNVQPYRYHKLYHHHNI
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND

Crispr_ID: NC_017297_6

• CRISPR_ID: NC_017297_6
• CRISPR_location: 2352681-2352908
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 3 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11

Consensus repeat of NC_017297_6

Consensus_repeat	Method
ATTTAAATACATCTTATGTTACTGTTCAAC	CRISPRCasFinder
ATTTAAATACATCTTATGTTACTGTTCAAC	CRT
ATTTAAATACATCTTATGTTACTGTTCAAC	PILER-CR

spacers of NC_017297_6

>6.1|2352711|36|NC_017297|CRISPRCasFinder,CRT
ACATAATCAGATGTTAGAAGTACTTCACGAATTAAG
>6.2|2352777|37|NC_017297|CRISPRCasFinder,CRT
TAGATAAAGATAGGACAATAGAATATTTTACATTAGA
>6.3|2352844|35|NC_017297|CRISPRCasFinder,CRT
GCGGCTATGGGAAACATAGAAGCTGAATCCGAATT
>6.4|2352713|36|NC_017297|PILER-CR
ACATAATCAGATGTTAGAAGTACTTCACGAATTAAG
>6.5|2352779|37|NC_017297|PILER-CR
TAGATAAAGATAGGACAATAGAATATTTTACATTAGA
>6.6|2352846|35|NC_017297|PILER-CR
GCGGCTATGGGAAACATAGAAGCTGAATCCGAATT

CRISPR arrays and Neighbor proteins around NC_017297_6

CRISPR arrays

The CRISPR arrays of NC_017297_6

>merge|NC_017297|6|2352681-2352908|CRISPRCasFinder,CRT,PILER-CR
GCTTAAATACATCTTATGTTAATGTTCAACACATAATCAGATGTTAGAAGTACTTCACGAATTAAGATTTAAATACATCTTATGTTACTGTTCAACTAGATAAAGATAGGACAATAGAATATTTTACATTAGAATTTAAATACATCTTATGTTACTGTTCAACGCGGCTATGGGAAACATAGAAGCTGAATCCGAATTATTTAAATACATCTTATGTTACTGTTCAAC

>NC_017297|6|6|2352681-2352908|CRISPRCasFinder
GCTTAAATACATCTTATGTTAATGTTCAAC	ACATAATCAGATGTTAGAAGTACTTCACGAATTAAG
ATTTAAATACATCTTATGTTACTGTTCAAC	TAGATAAAGATAGGACAATAGAATATTTTACATTAGA
ATTTAAATACATCTTATGTTACTGTTCAAC	GCGGCTATGGGAAACATAGAAGCTGAATCCGAATT
ATTTAAATACATCTTATGTTACTGTTCAAC

>NC_017297|6|1|2352681-2352908|CRT
GCTTAAATACATCTTATGTTAATGTTCAAC	ACATAATCAGATGTTAGAAGTACTTCACGAATTAAG
ATTTAAATACATCTTATGTTACTGTTCAAC	TAGATAAAGATAGGACAATAGAATATTTTACATTAGA
ATTTAAATACATCTTATGTTACTGTTCAAC	GCGGCTATGGGAAACATAGAAGCTGAATCCGAATT
ATTTAAATACATCTTATGTTACTGTTCAAC

>NC_017297|6|1|2352683-2352908|PILER-CR
TTAAATACATCTTATGTTAATGTTCAACAC	ATAATCAGATGTTAGAAGTACTTCACGAATTAAGAT
TTAAATACATCTTATGTTACTGTTCAACTA	GATAAAGATAGGACAATAGAATATTTTACATTAGAAT
TTAAATACATCTTATGTTACTGTTCAACGC	GGCTATGGGAAACATAGAAGCTGAATCCGAATTAT
TTAAATACATCTTATGTTACTGTTCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl|CDD|379915
NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein	unknown	unknown	unknown
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	unknown	unknown	gnl|CDD|236545
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	unknown	unknown	gnl|CDD|183481
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	unknown	unknown	gnl|CDD|340904
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl|CDD|236502
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|376899
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	unknown	unknown	gnl|CDD|379767
NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl|CDD|238129
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99905

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein	gnl|CDD|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000168002
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	gnl|CDD|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.72129e-11
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	gnl|CDD|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.79844e-156
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00629e-119
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.6734e-12
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.09381e-97
NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.49135e-104
NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC	gnl|CDD|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease	gnl|CDD|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.00217594
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	gnl|CDD|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.38777e-26
NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	1.55586e-29
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	gnl|CDD|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	7.73943e-38
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	gnl|CDD|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	8.26522e-29

Protein sequences

>NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein
MDKFRNMKKSHIALLAVMYIVLMGSLPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGNSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEDLTPCSVCNP
>NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNSYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNNLASVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPELLILVIVFITVEYILKRNFNKKISEQY
>NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYDKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPINFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKNRS
>NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYANK
>NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDEKVKSVAKYLEIEKVLDKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKATILMVTHDAFAASYAHRILFIKDGKIFNELVRGKDTRKEFFNKIIEVTSLLGGDDNNVF
>NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease
MIIMYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIKSSGGSYVSRLMEFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVTETSIVGVISLIAGLIIGMGVSQGLSVFALKLFEVSINEYRFAVSTRAISKTILYFGIMFLLVMIFNIFVISKYKIIDLLISGRKNENIKFKNTFIYLLSFVLCVVLLGFAYKSILKTGLKLREPMFKPSIAFVIVGTVLFFFSLAGVILYVVNKNKKIYFKGLNMFVVKQINSKVNTNFLSMSLICLMLFITILVLSTGISFKNGLEEGVRIRAPFDASIIISNNSKKDNLEDVLDKINFKKSKNEKYATCNEYISGVKLESLLSITDKDYKDAEVFFVKISDYNKILKLKGKKEINLNKDEILVMSTNNAVVKQANEKLKNSKKFNIKGKEYLVKNDTIIEENLATYLLADNVFTIVISDEFLYDYNKIVYSILNVTYSDKNREENNKKYSEINKNFVGGKYKSLNISYMGAFSKDDIYSGSKGGTTSILFVGIYLGLVFLITSMAVLALQQLSEASDSIERYKALKRIGASSKMIEKTIFLQTLIYFALPMILALVHSMIGIKVISDYIEVFTKIDISFSALITSLIFIVVYAGYFYTTYIGYKNIVESNI
>NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase
MLKFAYNTNGLRNMPLEEAIKQISNHNYDGIEISLHKQHFHPLNINIEEVKKIKSTVKSSGLVLSDIATGCDDILSDDKFEPSIICKDSIGRKKRIELLIKTAGFAEYLGVDVINFATGFKSDKVSNSEAYDYLKQGINYLLVKCPNTTFALEPEPDMFIEKTEQAIKLINEINTPRLMLNLDIGHVYCCEENPILSIRKSIPYARHIHIEDIKNRVHYHQIPGTGDIDFNTIFKDLIKYNYQHYISVELYHHADDWNNALDKSIKYLKQIEHHIRIVDSMELVQ
>NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPIKHIMSYPTDIRKRVENLPQYKDVIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSRGMVHFISII
>NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILRKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKIIREITEKDRKYYYKNYEFDIDDYKE
>NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSIEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGEFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIHDREKYLKNCAVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDKLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein
MKNKLKILIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANKYSAGFSLQTSKEPYEITVNYKANENLGEENYNKFWSDKKADKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKNLEQKYGNLKDLSKDNDSLKKFLNN
>NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein
MIYINLNTSYVKVQRTPVTIDGKEYTNLNTSYVNVQPYRYHKLYHHHNI
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND

Crispr_ID: NC_017297_5

• CRISPR_ID: NC_017297_5
• CRISPR_location: 2352134-2352426
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 4 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11

Consensus repeat of NC_017297_5

Consensus_repeat	Method
ATTTAAATACATCTTATGTTACTGTTCAAC	CRISPRCasFinder

spacers of NC_017297_5

>5.1|2352164|35|NC_017297|CRISPRCasFinder
GTATCTTCTAAGTTTTCTGTATTAGATATTTATGG
>5.2|2352229|35|NC_017297|CRISPRCasFinder
GAGAATGTATTTAAGAATACAATAAATGAATACAA
>5.3|2352294|36|NC_017297|CRISPRCasFinder
TAAAAAAGATCTACGGACAATTAGTAAAGCAATAAA
>5.4|2352360|36|NC_017297|CRISPRCasFinder
TCTTACTTTATTTATAGATAAAACAAAAGAAAGGAC

CRISPR arrays and Neighbor proteins around NC_017297_5

CRISPR arrays

The CRISPR arrays of NC_017297_5

>merge|NC_017297|5|2352134-2352426|CRISPRCasFinder
GCTTAAATACATCTCATGTTATTGCTCAATGTATCTTCTAAGTTTTCTGTATTAGATATTTATGGATTTAAATACATCCTATGTTAATGTTCAACGAGAATGTATTTAAGAATACAATAAATGAATACAAATTTAAATACATCTCATGTTAAGGTTCAACTAAAAAAGATCTACGGACAATTAGTAAAGCAATAAAATTTAAATACATCTCATGTTAAAGTTCAACTCTTACTTTATTTATAGATAAAACAAAAGAAAGGACATTTAAATACATCCTATGTTAATGTTCAATA

>NC_017297|5|5|2352134-2352426|CRISPRCasFinder
GCTTAAATACATCTCATGTTATTGCTCAAT	GTATCTTCTAAGTTTTCTGTATTAGATATTTATGG
ATTTAAATACATCCTATGTTAATGTTCAAC	GAGAATGTATTTAAGAATACAATAAATGAATACAA
ATTTAAATACATCTCATGTTAAGGTTCAAC	TAAAAAAGATCTACGGACAATTAGTAAAGCAATAAA
ATTTAAATACATCTCATGTTAAAGTTCAAC	TCTTACTTTATTTATAGATAAAACAAAAGAAAGGAC
ATTTAAATACATCCTATGTTAATGTTCAATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl|CDD|379915
NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein	unknown	unknown	unknown
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	unknown	unknown	gnl|CDD|236545
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	unknown	unknown	gnl|CDD|183481
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	unknown	unknown	gnl|CDD|340904
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC	unknown	unknown	gnl|CDD|236502
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|376899
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	unknown	unknown	gnl|CDD|379767
NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl|CDD|224007
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl|CDD|238129
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99905

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein	gnl|CDD|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	0.000168002
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	gnl|CDD|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.72129e-11
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	gnl|CDD|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.79844e-156
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00629e-119
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.6734e-12
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.09381e-97
NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.49135e-104
NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC	gnl|CDD|236502	PRK09410, ulaA, PTS system ascorbate-specific transporter subunit IIC; Reviewed.	0
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease	gnl|CDD|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.00217594
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	gnl|CDD|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.38777e-26
NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	1.55586e-29
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	gnl|CDD|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	7.73943e-38
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	gnl|CDD|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	8.26522e-29

Protein sequences

>NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein
MDKFRNMKKSHIALLAVMYIVLMGSLPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGNSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEDLTPCSVCNP
>NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNSYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNNLASVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPELLILVIVFITVEYILKRNFNKKISEQY
>NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYDKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPINFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKNRS
>NC_017297.1|WP_003358211.1|2346724_2348089_-|PTS-ascorbate-transporter-subunit-IIC
MLGLLQFLRDVLKQPALLMGIMALVGLVALKKPGHKVLTGTLKPILGYLMLGAGADFIVANLEPLGGMIQTGFNITGVVPNNEAIVAVAQKVLGVETMSILVVGLLINLVIARFTKYKYVFLTGHHSFFMACLLSAVLGTSGMKGTELILFGGFLLGAWSAISPAIGQKYTLKVTDGDEIAMGHFGSLAYYVSAWVGSKVGKPEESTENIEIPEKWGFLRDTTISTAITMMVFYIVAAVAAGPEYVSKLSDGMSPILFAIMSSLKFAVGVTIVYNGVRMILGDLIPAFQGIATKIIPDAIPAVDCAVFFPYAPTAVIIGFVSSFIGGIIGMVLLGVAGGVLIIPGLVPHFFCGSTAGIFGNATGGKKGAVIGSFVNGLLITFAPALLLPVLSTLGFKNTTFGDFDFGVLGIIIGKTSNLAGKTGIIIIAMLMLVALIVPNFIKTKSKALNNIEE
>NC_017297.1|WP_003358205.1|2343740_2344094_-|zinc-ribbon-domain-containing-protein
MIIWGWGKVTKKIIGAVFERTCNYCNTDEVWNLCVVRTWFTLFFIPIIPYKKQYCIACPKCWSYIELTQEEFEKIKIDITSSSNNINEKVVTDNIKYAGKTETQINYLKQMEEYANK
>NC_017297.1|WP_012100132.1|2342185_2342953_-|ABC-transporter-ATP-binding-protein
MQNILSVEKIEKYYGNKDNVTKAIDNISFKVDEGEFVGIMGPSGSGKTTLLNCISTIDNVTTGKIMINNNDITRLKSKSLDKFRQNELGFIFQDFNLLDTLTAYENIALALTIQGEKTSKIDEKVKSVAKYLEIEKVLDKYPYQMSGGQKQRVASARAIVTNPSLILADEPTGALDSKSARLLLERFEKLNKELKATILMVTHDAFAASYAHRILFIKDGKIFNELVRGKDTRKEFFNKIIEVTSLLGGDDNNVF
>NC_017297.1|WP_079992183.1|2340204_2342205_-|ABC-transporter-permease
MIIMYSKIALKNIKKSYKDYTIYFLTLILAVCIFYSFNSIDSQKALTDIKSSGGSYVSRLMEFMSAVSVFVSIILGSLILYANNFLIKKRKKELGIYMILGMGKRKISKILVTETSIVGVISLIAGLIIGMGVSQGLSVFALKLFEVSINEYRFAVSTRAISKTILYFGIMFLLVMIFNIFVISKYKIIDLLISGRKNENIKFKNTFIYLLSFVLCVVLLGFAYKSILKTGLKLREPMFKPSIAFVIVGTVLFFFSLAGVILYVVNKNKKIYFKGLNMFVVKQINSKVNTNFLSMSLICLMLFITILVLSTGISFKNGLEEGVRIRAPFDASIIISNNSKKDNLEDVLDKINFKKSKNEKYATCNEYISGVKLESLLSITDKDYKDAEVFFVKISDYNKILKLKGKKEINLNKDEILVMSTNNAVVKQANEKLKNSKKFNIKGKEYLVKNDTIIEENLATYLLADNVFTIVISDEFLYDYNKIVYSILNVTYSDKNREENNKKYSEINKNFVGGKYKSLNISYMGAFSKDDIYSGSKGGTTSILFVGIYLGLVFLITSMAVLALQQLSEASDSIERYKALKRIGASSKMIEKTIFLQTLIYFALPMILALVHSMIGIKVISDYIEVFTKIDISFSALITSLIFIVVYAGYFYTTYIGYKNIVESNI
>NC_017297.1|WP_012100129.1|2337558_2338416_-|sugar-phosphate-isomerase/epimerase
MLKFAYNTNGLRNMPLEEAIKQISNHNYDGIEISLHKQHFHPLNINIEEVKKIKSTVKSSGLVLSDIATGCDDILSDDKFEPSIICKDSIGRKKRIELLIKTAGFAEYLGVDVINFATGFKSDKVSNSEAYDYLKQGINYLLVKCPNTTFALEPEPDMFIEKTEQAIKLINEINTPRLMLNLDIGHVYCCEENPILSIRKSIPYARHIHIEDIKNRVHYHQIPGTGDIDFNTIFKDLIKYNYQHYISVELYHHADDWNNALDKSIKYLKQIEHHIRIVDSMELVQ
>NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPIKHIMSYPTDIRKRVENLPQYKDVIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSRGMVHFISII
>NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILRKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKIIREITEKDRKYYYKNYEFDIDDYKE
>NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSIEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGEFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIHDREKYLKNCAVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDKLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein
MKNKLKILIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANKYSAGFSLQTSKEPYEITVNYKANENLGEENYNKFWSDKKADKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKNLEQKYGNLKDLSKDNDSLKKFLNN
>NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein
MIYINLNTSYVKVQRTPVTIDGKEYTNLNTSYVNVQPYRYHKLYHHHNI
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND

Crispr_ID: NC_017297_7

• CRISPR_ID: NC_017297_7
• CRISPR_location: 2359490-2359780
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 4 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11,cmr4gr7,csx1,cmr3gr5,cas10,cmr1gr7

Consensus repeat of NC_017297_7

Consensus_repeat	Method
ATTTAAATACATCTTATGTTATTGTTCAAC	CRT
TTAAATACATCTTATGTTAATGTTCAAC	CRISPRCasFinder
TAATTTAAATACATCTTATGTTATTGTTCAAC	PILER-CR

spacers of NC_017297_7

>7.1|2359520|35|NC_017297|CRT
ATAGATGAAATAGAAATAGTTATAGATTTAATTGA
>7.2|2359585|36|NC_017297|CRT
GTTAAAGAAGATGAAAAAAGTAAATAGGTGATATTA
>7.3|2359651|35|NC_017297|CRT
GGACATGAAGATATACTAGCCACACCGTTAGACTA
>7.4|2359716|34|NC_017297|CRT
ATAATAAATATGCATGTGAATATGTACTTAGCTT
>7.5|2359520|37|NC_017297|CRISPRCasFinder
ATAGATGAAATAGAAATAGTTATAGATTTAATTGAAT
>7.6|2359585|38|NC_017297|CRISPRCasFinder
GTTAAAGAAGATGAAAAAAGTAAATAGGTGATATTAAT
>7.7|2359651|37|NC_017297|CRISPRCasFinder
GGACATGAAGATATACTAGCCACACCGTTAGACTAAT
>7.8|2359716|36|NC_017297|CRISPRCasFinder
ATAATAAATATGCATGTGAATATGTACTTAGCTTAT
>7.9|2359586|34|NC_017297|PILER-CR
GTTAAAGAAGATGAAAAAAGTAAATAGGTGATAT
>7.10|2359652|33|NC_017297|PILER-CR
GGACATGAAGATATACTAGCCACACCGTTAGAC
>7.11|2359717|32|NC_017297|PILER-CR
ATAATAAATATGCATGTGAATATGTACTTAGC

CRISPR arrays and Neighbor proteins around NC_017297_7

CRISPR arrays

The CRISPR arrays of NC_017297_7

>merge|NC_017297|7|2359490-2359780|CRT,CRISPRCasFinder,PILER-CR
GCTCAAATACATCTTATGTTATTGTTCAACATAGATGAAATAGAAATAGTTATAGATTTAATTGAATTTAAATACATCTTATGTTATTGTTCAACGTTAAAGAAGATGAAAAAAGTAAATAGGTGATATTAATTTAAATACATCTTATGTTATTGTTCAACGGACATGAAGATATACTAGCCACACCGTTAGACTAATTTAAATACATCTTATGTTATTGTTCAACATAATAAATATGCATGTGAATATGTACTTAGCTTATTTAAATACATCTCATGTTATTGTTCAACC

>NC_017297|7|2|2359490-2359779|CRT
GCTCAAATACATCTTATGTTATTGTTCAAC	ATAGATGAAATAGAAATAGTTATAGATTTAATTGA
ATTTAAATACATCTTATGTTATTGTTCAAC	GTTAAAGAAGATGAAAAAAGTAAATAGGTGATATTA
ATTTAAATACATCTTATGTTATTGTTCAAC	GGACATGAAGATATACTAGCCACACCGTTAGACTA
ATTTAAATACATCTTATGTTATTGTTCAAC	ATAATAAATATGCATGTGAATATGTACTTAGCTT
ATTTAAATACATCTCATGTTATTGTTCAAC

>NC_017297|7|7|2359492-2359780|CRISPRCasFinder
TCAAATACATCTTATGTTATTGTTCAAC	ATAGATGAAATAGAAATAGTTATAGATTTAATTGAAT
TTAAATACATCTTATGTTATTGTTCAAC	GTTAAAGAAGATGAAAAAAGTAAATAGGTGATATTAAT
TTAAATACATCTTATGTTATTGTTCAAC	GGACATGAAGATATACTAGCCACACCGTTAGACTAAT
TTAAATACATCTTATGTTATTGTTCAAC	ATAATAAATATGCATGTGAATATGTACTTAGCTTAT
TTAAATACATCTCATGTTATTGTTCAACC

>NC_017297|7|2|2359554-2359779|PILER-CR
AATTTAAATACATCTTATGTTATTGTTCAACG	TTAAAGAAGATGAAAAAAGTAAATAGGTGATATT
AATTTAAATACATCTTATGTTATTGTTCAACG	GACATGAAGATATACTAGCCACACCGTTAGACT
AATTTAAATACATCTTATGTTATTGTTCAACA	TAATAAATATGCATGTGAATATGTACTTAGCT
TATTTAAATACATCTCATGTTATTGTTCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein	unknown	unknown	unknown
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	unknown	unknown	gnl|CDD|379767
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	unknown	unknown	gnl|CDD|183481
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	unknown
NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	unknown	unknown	gnl|CDD|340904
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	unknown	unknown	gnl|CDD|236545
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl|CDD|238129
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99905

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	2.8e-81	268.4	0.0
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	9.3e-18	59.1	22.6
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	9.5e-154	507.1	32.1
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	2.1e-37	123.7	34.8
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.3e-66	219.0	0.1
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.18416e-65
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	gnl|CDD|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.72129e-11
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	gnl|CDD|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.79844e-156
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.35159e-25
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00629e-119
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	gnl|CDD|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.38777e-26
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.09381e-97
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.6734e-12
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.54325e-13
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.56161e-106
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	gnl|CDD|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	7.73943e-38
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	gnl|CDD|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	8.26522e-29

Protein sequences

>NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein
MKNKLKILIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANKYSAGFSLQTSKEPYEITVNYKANENLGEENYNKFWSDKKADKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKNLEQKYGNLKDLSKDNDSLKKFLNN
>NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIHDREKYLKNCAVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDKLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSIEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGEFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILRKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKIIREITEKDRKYYYKNYEFDIDDYKE
>NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPIKHIMSYPTDIRKRVENLPQYKDVIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSRGMVHFISII
>NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein
MDKFRNMKKSHIALLAVMYIVLMGSLPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGNSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEDLTPCSVCNP
>NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNSYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNNLASVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPELLILVIVFITVEYILKRNFNKKISEQY
>NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYDKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPINFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKNRS
>NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein
MIYINLNTSYVKVQRTPVTIDGKEYTNLNTSYVNVQPYRYHKLYHHHNI
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND
>NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYKDKETIYIKAISPIHAGSGQSLTSVDMPIQRESHSNIPKIEGSSLKGSVKHNVYHKLRVNKDNKKEEHKLFEKMFGSEDGNDCASAISITDAKLLLFPMRSAIDIYKLITCPYVLKRWKEETNQSFEDSILENIEDGHCVINQNSPLLSNDKVMLEEYIFEARKEDLSILFNGSFENLQINKVVILSDSDFIDMVTMYTEVITRNKINVETGTAQGTGLFSEEYLPAETVMYFSVLESAFYKGEEEVLKYFNENIGGIFQVGGNETIGKGIVKVINHDLLKGVTE
>NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein
MEHKNVEHLVIFSTLNQITNYIAIKNLKPKNIYNITFDQGFADTLKQGIDPKKWDDNLKNVLNDENIKPKRKNIEIKQCMYIDLEKFKEELEKNIEYVDEDTPIYWHITGGQRIFAIAIHDIVKKRPNDIIFYLEGNSEKIIYIGKEKTKFEYELKDLDFSTAFKLMGYNTEDLDSTRILKGKIKKNDKNEKLKYDKNEMKFYHRLYDWIINNDGEKTKSHIAFSIGDKKFEGTFKKLLLESNSINRTIRQEFLKKLFEELEKKSPSLKKIEYNFINSDEMKMEFPAGYIFEKLTGYQIYKVVEDNTRILGMAMSLKVYNEEGGHSTDELDIALLTNTGRIINFECKSGSLKGDNAKSHKFTTYSLSGVFGAPIFLTPLTYKGEKLEKELDKKLHSACKAADRANLEKIYLKDIKEKVKKLIG
>NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3
MKFLKIKPYDNTFFRLGNNFEFKISNVIQTKNVAYPSTFFGAIFTAILANNDEFRESFLNIPGNTDHLEILNIKQIYLYAEKQGMIYIKAPKDIFVNNNEVKFGNFKEIKDGESSIKYDYYLEEPDGNELERADNYFVSIKEFYDKYRYKVLDNIDLKQEDEIFAKNIKTGIALDKSTGIVKESLLYTIEQTEFKNITEDYYSNDWSFVVEYAIDNDFLKKQGYPKVKNLDKGELKLGGETKVCTYEIIENSDINEFKSKTSQGFLKPGEKLKVILTSDSYFTKSFAELFNDEMKILALVNDKPIYIGGFDVAKNEEKAMYKGYSAGTVLLLQNESGKDINLQKYLDMKLRNKLKNGFNEYICVKGE
>NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSYLLGVTVGPIQTNIQKSRKLRELYNSSKIVSDMMKKVIEYLKIRDETLKIIYPSIKDVNDTKTDITNYLICEINNIDDLKDMRERVFDELKISVLEEIYFMFWAVEPLEEYSKTYKKLTKKLRSIKNTYEFKNYEKDVRIKKKCSLCGERIREDASELCEVCNRKRNYDQTSNWKNNNKGEKYKSVYDISIDAWKEKYNEDLLSLNKNLEDLFNNTSRYYSLDTVSNIIKCLKIDPKKVRKEKEIDEDLENPKMEALELIAELKNIRFELESIYLRGEKPVSKPHYKYCFIQIDVDDLGKWISGVYNYEEENLKENQIQISKALCSFAYKLKEEFKNSKTKVIYAGGDDFLAVLPVECLLNTLKIIEEIFKSTVQNNIDNSLNYSQKISYSASVTIANCKDEMSLALRKNREALEKVKNRYYSKNGICINYIINTSKIINMFLLKDYFNEYVDNLRYFKKVEKYMSFTYIDAIENEFSKMKFEDLETDDFLNIKDMLLLEFERHLNLNKNKVPKDSEEGNENFLEYFKIHTRLFENIINDNEIDKKIDFINIINCFRIYKKLTDFQFKEEAKWDEVSKN
>NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MERVKVTLGVVTDMFSEGVNSNKEAEFRITELKALLRSTFREFFYYTSLDDLKEKEELLFGSTNRKSPVIIKFGRNNKIRFKDKKKLVLHKNMFKEAIPSGTTINIIFQSRYEKYLKTYVYTLKLASIMGALGKRSRKGMGAFKIIKIDDNEIIDINKSVEDLLCGYEEQFKINEKIYLIKTRKLLKEKQYKDNCTKYKIECDANMPKNVNYVKNIYKIYLGNLTEEKSRNKIDCTLRNFSWLNHYRLSDLNKIFSNETIKKIEKETGKRIDNEISLENLFNKEILGNYNYKYKEKEVTKKNILTRFACPVYVTIYQKSRGELIENYLIIKELNYDYVYKKILDKKVSNKKVTEQKKEEIRTDIKSELKEMKPIDKYYVEEFVKKIIECCEVK

Crispr_ID: NC_017297_8

• CRISPR_ID: NC_017297_8
• CRISPR_location: 2360034-2360193
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 2 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11,cmr4gr7,csx1,cmr3gr5,cas10,cmr1gr7

Consensus repeat of NC_017297_8

Consensus_repeat	Method
TTAAATACATCTTATGTTAATGTTCAAC	CRISPRCasFinder

spacers of NC_017297_8

>8.1|2360062|38|NC_017297|CRISPRCasFinder
AAATAGTATAGAGCTACAAATAGAAAAGGCAAGAATAT
>8.2|2360128|37|NC_017297|CRISPRCasFinder
AGAGGAGCCAATAGACATTGCAAGATATTAGATACAT

CRISPR arrays and Neighbor proteins around NC_017297_8

CRISPR arrays

The CRISPR arrays of NC_017297_8

>merge|NC_017297|8|2360034-2360193|CRISPRCasFinder
TTAAATACATCTCATGTTAATGTTCAACAAATAGTATAGAGCTACAAATAGAAAAGGCAAGAATATTTAAATACATCCCATGTTAATGTTCAAGAGAGGAGCCAATAGACATTGCAAGATATTAGATACATTTAAATACATCTCATGTTACTGCTCAACC

>NC_017297|8|8|2360034-2360193|CRISPRCasFinder
TTAAATACATCTCATGTTAATGTTCAAC	AAATAGTATAGAGCTACAAATAGAAAAGGCAAGAATAT
TTAAATACATCCCATGTTAATGTTCAAG	AGAGGAGCCAATAGACATTGCAAGATATTAGATACAT
TTAAATACATCTCATGTTACTGCTCAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein	unknown	unknown	unknown
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	unknown	unknown	gnl|CDD|379767
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	unknown	unknown	gnl|CDD|183481
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	unknown
NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	unknown	unknown	gnl|CDD|340904
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	unknown	unknown	gnl|CDD|236545
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl|CDD|238129
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99905

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	2.8e-81	268.4	0.0
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	9.3e-18	59.1	22.6
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	9.5e-154	507.1	32.1
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	2.1e-37	123.7	34.8
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.3e-66	219.0	0.1
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.18416e-65
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	gnl|CDD|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.72129e-11
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	gnl|CDD|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.79844e-156
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.35159e-25
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00629e-119
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	gnl|CDD|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.38777e-26
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.09381e-97
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.6734e-12
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.54325e-13
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.56161e-106
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	gnl|CDD|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	7.73943e-38
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	gnl|CDD|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	8.26522e-29

Protein sequences

>NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein
MKNKLKILIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANKYSAGFSLQTSKEPYEITVNYKANENLGEENYNKFWSDKKADKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKNLEQKYGNLKDLSKDNDSLKKFLNN
>NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIHDREKYLKNCAVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDKLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSIEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGEFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILRKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKIIREITEKDRKYYYKNYEFDIDDYKE
>NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPIKHIMSYPTDIRKRVENLPQYKDVIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSRGMVHFISII
>NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein
MDKFRNMKKSHIALLAVMYIVLMGSLPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGNSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEDLTPCSVCNP
>NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNSYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNNLASVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPELLILVIVFITVEYILKRNFNKKISEQY
>NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYDKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPINFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKNRS
>NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein
MIYINLNTSYVKVQRTPVTIDGKEYTNLNTSYVNVQPYRYHKLYHHHNI
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND
>NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYKDKETIYIKAISPIHAGSGQSLTSVDMPIQRESHSNIPKIEGSSLKGSVKHNVYHKLRVNKDNKKEEHKLFEKMFGSEDGNDCASAISITDAKLLLFPMRSAIDIYKLITCPYVLKRWKEETNQSFEDSILENIEDGHCVINQNSPLLSNDKVMLEEYIFEARKEDLSILFNGSFENLQINKVVILSDSDFIDMVTMYTEVITRNKINVETGTAQGTGLFSEEYLPAETVMYFSVLESAFYKGEEEVLKYFNENIGGIFQVGGNETIGKGIVKVINHDLLKGVTE
>NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein
MEHKNVEHLVIFSTLNQITNYIAIKNLKPKNIYNITFDQGFADTLKQGIDPKKWDDNLKNVLNDENIKPKRKNIEIKQCMYIDLEKFKEELEKNIEYVDEDTPIYWHITGGQRIFAIAIHDIVKKRPNDIIFYLEGNSEKIIYIGKEKTKFEYELKDLDFSTAFKLMGYNTEDLDSTRILKGKIKKNDKNEKLKYDKNEMKFYHRLYDWIINNDGEKTKSHIAFSIGDKKFEGTFKKLLLESNSINRTIRQEFLKKLFEELEKKSPSLKKIEYNFINSDEMKMEFPAGYIFEKLTGYQIYKVVEDNTRILGMAMSLKVYNEEGGHSTDELDIALLTNTGRIINFECKSGSLKGDNAKSHKFTTYSLSGVFGAPIFLTPLTYKGEKLEKELDKKLHSACKAADRANLEKIYLKDIKEKVKKLIG
>NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3
MKFLKIKPYDNTFFRLGNNFEFKISNVIQTKNVAYPSTFFGAIFTAILANNDEFRESFLNIPGNTDHLEILNIKQIYLYAEKQGMIYIKAPKDIFVNNNEVKFGNFKEIKDGESSIKYDYYLEEPDGNELERADNYFVSIKEFYDKYRYKVLDNIDLKQEDEIFAKNIKTGIALDKSTGIVKESLLYTIEQTEFKNITEDYYSNDWSFVVEYAIDNDFLKKQGYPKVKNLDKGELKLGGETKVCTYEIIENSDINEFKSKTSQGFLKPGEKLKVILTSDSYFTKSFAELFNDEMKILALVNDKPIYIGGFDVAKNEEKAMYKGYSAGTVLLLQNESGKDINLQKYLDMKLRNKLKNGFNEYICVKGE
>NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSYLLGVTVGPIQTNIQKSRKLRELYNSSKIVSDMMKKVIEYLKIRDETLKIIYPSIKDVNDTKTDITNYLICEINNIDDLKDMRERVFDELKISVLEEIYFMFWAVEPLEEYSKTYKKLTKKLRSIKNTYEFKNYEKDVRIKKKCSLCGERIREDASELCEVCNRKRNYDQTSNWKNNNKGEKYKSVYDISIDAWKEKYNEDLLSLNKNLEDLFNNTSRYYSLDTVSNIIKCLKIDPKKVRKEKEIDEDLENPKMEALELIAELKNIRFELESIYLRGEKPVSKPHYKYCFIQIDVDDLGKWISGVYNYEEENLKENQIQISKALCSFAYKLKEEFKNSKTKVIYAGGDDFLAVLPVECLLNTLKIIEEIFKSTVQNNIDNSLNYSQKISYSASVTIANCKDEMSLALRKNREALEKVKNRYYSKNGICINYIINTSKIINMFLLKDYFNEYVDNLRYFKKVEKYMSFTYIDAIENEFSKMKFEDLETDDFLNIKDMLLLEFERHLNLNKNKVPKDSEEGNENFLEYFKIHTRLFENIINDNEIDKKIDFINIINCFRIYKKLTDFQFKEEAKWDEVSKN
>NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MERVKVTLGVVTDMFSEGVNSNKEAEFRITELKALLRSTFREFFYYTSLDDLKEKEELLFGSTNRKSPVIIKFGRNNKIRFKDKKKLVLHKNMFKEAIPSGTTINIIFQSRYEKYLKTYVYTLKLASIMGALGKRSRKGMGAFKIIKIDDNEIIDINKSVEDLLCGYEEQFKINEKIYLIKTRKLLKEKQYKDNCTKYKIECDANMPKNVNYVKNIYKIYLGNLTEEKSRNKIDCTLRNFSWLNHYRLSDLNKIFSNETIKKIEKETGKRIDNEISLENLFNKEILGNYNYKYKEKEVTKKNILTRFACPVYVTIYQKSRGELIENYLIIKELNYDYVYKKILDKKVSNKKVTEQKKEEIRTDIKSELKEMKPIDKYYVEEFVKKIIECCEVK

Crispr_ID: NC_017297_10

• CRISPR_ID: NC_017297_10
• CRISPR_location: 2361041-2361200
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 2 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11,cmr4gr7,csx1,cmr3gr5,cas10,cmr1gr7,cas6

Consensus repeat of NC_017297_10

Consensus_repeat	Method
TTAAATACATCTTATGTTAATGTTCAAC	CRISPRCasFinder

spacers of NC_017297_10

>10.1|2361069|38|NC_017297|CRISPRCasFinder
ATCCTTCCTTATTTCTACATATGGTCGTCAAATGAATT
>10.2|2361135|38|NC_017297|CRISPRCasFinder
AAAAATATCCTTCTTGATTTACCCTCCTTATCTTTTAT

CRISPR arrays and Neighbor proteins around NC_017297_10

CRISPR arrays

The CRISPR arrays of NC_017297_10

>merge|NC_017297|10|2361041-2361200|CRISPRCasFinder
TTAAATACCTCATATGTTATTGTTCAACATCCTTCCTTATTTCTACATATGGTCGTCAAATGAATTTTAAATACATCTTATGTTATTGTTCAATAAAAATATCCTTCTTGATTTACCCTCCTTATCTTTTATTTAAATACATCTTATGTTATTGTTCAAT

>NC_017297|10|10|2361041-2361200|CRISPRCasFinder
TTAAATACCTCATATGTTATTGTTCAAC	ATCCTTCCTTATTTCTACATATGGTCGTCAAATGAATT
TTAAATACATCTTATGTTATTGTTCAAT	AAAAATATCCTTCTTGATTTACCCTCCTTATCTTTTAT
TTAAATACATCTTATGTTATTGTTCAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein	unknown	unknown	unknown
NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	unknown	unknown	gnl|CDD|183481
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	unknown
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	unknown	unknown	gnl|CDD|340904
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	unknown	unknown	gnl|CDD|236545
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	unknown	unknown	gnl|CDD|379767
NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl|CDD|238129
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	2.8e-81	268.4	0.0
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	9.3e-18	59.1	22.6
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	9.5e-154	507.1	32.1
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	2.1e-37	123.7	34.8
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	2e-27	91.5	8.3
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.3e-66	219.0	0.1
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	gnl|CDD|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.72129e-11
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	gnl|CDD|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.79844e-156
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.6734e-12
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.35159e-25
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00629e-119
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	gnl|CDD|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.38777e-26
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.09381e-97
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	gnl|CDD|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	7.73943e-38
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.54325e-13
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.56161e-106
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.18416e-65
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.97178e-20

Protein sequences

>NC_017297.1|WP_154018626.1|2360525_2360675_+|hypothetical-protein
MIYINLNTSYVKVQRTPVTIDGKEYTNLNTSYVNVQPYRYHKLYHHHNI
>NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein
MKNKLKILIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANKYSAGFSLQTSKEPYEITVNYKANENLGEENYNKFWSDKKADKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKNLEQKYGNLKDLSKDNDSLKKFLNN
>NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIHDREKYLKNCAVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDKLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSIEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGEFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILRKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKIIREITEKDRKYYYKNYEFDIDDYKE
>NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPIKHIMSYPTDIRKRVENLPQYKDVIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSRGMVHFISII
>NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein
MDKFRNMKKSHIALLAVMYIVLMGSLPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGNSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEDLTPCSVCNP
>NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNSYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNNLASVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPELLILVIVFITVEYILKRNFNKKISEQY
>NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYDKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPINFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND
>NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYKDKETIYIKAISPIHAGSGQSLTSVDMPIQRESHSNIPKIEGSSLKGSVKHNVYHKLRVNKDNKKEEHKLFEKMFGSEDGNDCASAISITDAKLLLFPMRSAIDIYKLITCPYVLKRWKEETNQSFEDSILENIEDGHCVINQNSPLLSNDKVMLEEYIFEARKEDLSILFNGSFENLQINKVVILSDSDFIDMVTMYTEVITRNKINVETGTAQGTGLFSEEYLPAETVMYFSVLESAFYKGEEEVLKYFNENIGGIFQVGGNETIGKGIVKVINHDLLKGVTE
>NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein
MEHKNVEHLVIFSTLNQITNYIAIKNLKPKNIYNITFDQGFADTLKQGIDPKKWDDNLKNVLNDENIKPKRKNIEIKQCMYIDLEKFKEELEKNIEYVDEDTPIYWHITGGQRIFAIAIHDIVKKRPNDIIFYLEGNSEKIIYIGKEKTKFEYELKDLDFSTAFKLMGYNTEDLDSTRILKGKIKKNDKNEKLKYDKNEMKFYHRLYDWIINNDGEKTKSHIAFSIGDKKFEGTFKKLLLESNSINRTIRQEFLKKLFEELEKKSPSLKKIEYNFINSDEMKMEFPAGYIFEKLTGYQIYKVVEDNTRILGMAMSLKVYNEEGGHSTDELDIALLTNTGRIINFECKSGSLKGDNAKSHKFTTYSLSGVFGAPIFLTPLTYKGEKLEKELDKKLHSACKAADRANLEKIYLKDIKEKVKKLIG
>NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3
MKFLKIKPYDNTFFRLGNNFEFKISNVIQTKNVAYPSTFFGAIFTAILANNDEFRESFLNIPGNTDHLEILNIKQIYLYAEKQGMIYIKAPKDIFVNNNEVKFGNFKEIKDGESSIKYDYYLEEPDGNELERADNYFVSIKEFYDKYRYKVLDNIDLKQEDEIFAKNIKTGIALDKSTGIVKESLLYTIEQTEFKNITEDYYSNDWSFVVEYAIDNDFLKKQGYPKVKNLDKGELKLGGETKVCTYEIIENSDINEFKSKTSQGFLKPGEKLKVILTSDSYFTKSFAELFNDEMKILALVNDKPIYIGGFDVAKNEEKAMYKGYSAGTVLLLQNESGKDINLQKYLDMKLRNKLKNGFNEYICVKGE
>NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSYLLGVTVGPIQTNIQKSRKLRELYNSSKIVSDMMKKVIEYLKIRDETLKIIYPSIKDVNDTKTDITNYLICEINNIDDLKDMRERVFDELKISVLEEIYFMFWAVEPLEEYSKTYKKLTKKLRSIKNTYEFKNYEKDVRIKKKCSLCGERIREDASELCEVCNRKRNYDQTSNWKNNNKGEKYKSVYDISIDAWKEKYNEDLLSLNKNLEDLFNNTSRYYSLDTVSNIIKCLKIDPKKVRKEKEIDEDLENPKMEALELIAELKNIRFELESIYLRGEKPVSKPHYKYCFIQIDVDDLGKWISGVYNYEEENLKENQIQISKALCSFAYKLKEEFKNSKTKVIYAGGDDFLAVLPVECLLNTLKIIEEIFKSTVQNNIDNSLNYSQKISYSASVTIANCKDEMSLALRKNREALEKVKNRYYSKNGICINYIINTSKIINMFLLKDYFNEYVDNLRYFKKVEKYMSFTYIDAIENEFSKMKFEDLETDDFLNIKDMLLLEFERHLNLNKNKVPKDSEEGNENFLEYFKIHTRLFENIINDNEIDKKIDFINIINCFRIYKKLTDFQFKEEAKWDEVSKN
>NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MERVKVTLGVVTDMFSEGVNSNKEAEFRITELKALLRSTFREFFYYTSLDDLKEKEELLFGSTNRKSPVIIKFGRNNKIRFKDKKKLVLHKNMFKEAIPSGTTINIIFQSRYEKYLKTYVYTLKLASIMGALGKRSRKGMGAFKIIKIDDNEIIDINKSVEDLLCGYEEQFKINEKIYLIKTRKLLKEKQYKDNCTKYKIECDANMPKNVNYVKNIYKIYLGNLTEEKSRNKIDCTLRNFSWLNHYRLSDLNKIFSNETIKKIEKETGKRIDNEISLENLFNKEILGNYNYKYKEKEVTKKNILTRFACPVYVTIYQKSRGELIENYLIIKELNYDYVYKKILDKKVSNKKVTEQKKEEIRTDIKSELKEMKPIDKYYVEEFVKKIIECCEVK
>NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6
MEFWELIVTAMLKKDIYFEDCGYIIGKNINKSMLWDKDLKEVHPKKQYKNYVFNSFYPIERDKFYKKDRLYIFNIRGLSKEFIDKIETCLCNLESNDFNVISTSKKEIKQRYIKELYTQTPLIITVDDKPWLQNDGDLDLFKQRLEDNLEKKYKSFFNEDIDVKGKFIKSIEFKNRKPMHYNYKNGKKLLANKVSIQIEDNEEAQKVAFLARAIGLGEKNPSIGAGFCK

Crispr_ID: NC_017297_9

• CRISPR_ID: NC_017297_9
• CRISPR_location: 2360473-2360766
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 4 spacers
• Cas_protein_info: cmr6gr7,cmr5gr11,cmr4gr7,csx1,cmr3gr5,cas10,cmr1gr7,cas6

Consensus repeat of NC_017297_9

Consensus_repeat	Method
ATTTAAATACATCTTATGTTAATGTTCAAC	CRT
ATTTAAATACATCTTATGTTAATGTTCAAC	PILER-CR
TTAAATACATCTTATGTTAATGTTCAAC	CRISPRCasFinder

spacers of NC_017297_9

>9.1|2360503|36|NC_017297|CRT
TTTAGAAAAAAATAACGCTTTTGATGATTTATATAA
>9.2|2360569|36|NC_017297|CRT
GAACACCAGTTACAATAGATGGAAAAGAATATACAA
>9.3|2360635|35|NC_017297|CRT
CTTATCGCTATCATAAACTATATCACCATCATAAT
>9.4|2360700|36|NC_017297|CRT
AGGTGAAGAAATTGGAGATACTTTAGAAGCAGTTTG
>9.5|2360505|36|NC_017297|PILER-CR
TTTAGAAAAAAATAACGCTTTTGATGATTTATATAA
>9.6|2360571|36|NC_017297|PILER-CR
GAACACCAGTTACAATAGATGGAAAAGAATATACAA
>9.7|2360637|35|NC_017297|PILER-CR
CTTATCGCTATCATAAACTATATCACCATCATAAT
>9.8|2360503|38|NC_017297|CRISPRCasFinder
TTTAGAAAAAAATAACGCTTTTGATGATTTATATAAAT
>9.9|2360569|38|NC_017297|CRISPRCasFinder
GAACACCAGTTACAATAGATGGAAAAGAATATACAAAT
>9.10|2360635|37|NC_017297|CRISPRCasFinder
CTTATCGCTATCATAAACTATATCACCATCATAATAT
>9.11|2360700|38|NC_017297|CRISPRCasFinder
AGGTGAAGAAATTGGAGATACTTTAGAAGCAGTTTGAT

CRISPR arrays and Neighbor proteins around NC_017297_9

CRISPR arrays

The CRISPR arrays of NC_017297_9

>merge|NC_017297|9|2360473-2360766|CRT,PILER-CR,CRISPRCasFinder
GCTTAAATACATCTTATGTTAATGTTCAACTTTAGAAAAAAATAACGCTTTTGATGATTTATATAAATTTAAATACATCTTATGTTAAGGTTCAACGAACACCAGTTACAATAGATGGAAAAGAATATACAAATTTAAATACATCTTATGTTAATGTTCAACCTTATCGCTATCATAAACTATATCACCATCATAATATTTAAATACATCTTATGTTAATATTCAACAGGTGAAGAAATTGGAGATACTTTAGAAGCAGTTTGATTTAAATACATCTTATGTTAATGTTCAACC

>NC_017297|9|3|2360473-2360765|CRT
GCTTAAATACATCTTATGTTAATGTTCAAC	TTTAGAAAAAAATAACGCTTTTGATGATTTATATAA
ATTTAAATACATCTTATGTTAAGGTTCAAC	GAACACCAGTTACAATAGATGGAAAAGAATATACAA
ATTTAAATACATCTTATGTTAATGTTCAAC	CTTATCGCTATCATAAACTATATCACCATCATAAT
ATTTAAATACATCTTATGTTAATATTCAAC	AGGTGAAGAAATTGGAGATACTTTAGAAGCAGTTTG
ATTTAAATACATCTTATGTTAATGTTCAAC

>NC_017297|9|3|2360475-2360699|PILER-CR
TTAAATACATCTTATGTTAATGTTCAACTT	TAGAAAAAAATAACGCTTTTGATGATTTATATAAAT
TTAAATACATCTTATGTTAAGGTTCAACGA	ACACCAGTTACAATAGATGGAAAAGAATATACAAAT
TTAAATACATCTTATGTTAATGTTCAACCT	TATCGCTATCATAAACTATATCACCATCATAATAT
TTAAATACATCTTATGTTAATATTCAAC

>NC_017297|9|9|2360475-2360766|CRISPRCasFinder
TTAAATACATCTTATGTTAATGTTCAAC	TTTAGAAAAAAATAACGCTTTTGATGATTTATATAAAT
TTAAATACATCTTATGTTAAGGTTCAAC	GAACACCAGTTACAATAGATGGAAAAGAATATACAAAT
TTAAATACATCTTATGTTAATGTTCAAC	CTTATCGCTATCATAAACTATATCACCATCATAATAT
TTAAATACATCTTATGTTAATATTCAAC	AGGTGAAGAAATTGGAGATACTTTAGAAGCAGTTTGAT
TTAAATACATCTTATGTTAATGTTCAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein	unknown	unknown	unknown
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	unknown	unknown	gnl|CDD|379767
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	unknown	unknown	gnl|CDD|183481
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	unknown
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	unknown	unknown	gnl|CDD|340904
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	unknown	unknown	gnl|CDD|236545
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	unknown	unknown	gnl|CDD|100047
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl|CDD|238129
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl|CDD|99905

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	2.8e-81	268.4	0.0
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	9.3e-18	59.1	22.6
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	9.5e-154	507.1	32.1
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	2.1e-37	123.7	34.8
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	2e-27	91.5	8.3
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.3e-66	219.0	0.1
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.18416e-65
NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein	gnl|CDD|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.72129e-11
NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase	gnl|CDD|183481	PRK12376, PRK12376, putative translaldolase; Provisional.	3.79844e-156
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.35159e-25
NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.00629e-119
NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein	gnl|CDD|379767	pfam16107, DUF4825, Domain of unknown function (DUF4825). This domain forms the N-terminal, extracellular domain of some homologs of Staph BlaR1 proteases, where it replaces the penicillin-binding domain of BlaR1. It is also found in many uncharacterized proteins in a broad range of bacteria. Its association with BlaR1 homologs suggests it may be involved in substrate-, possibly antibiotic-binding, but this prediction has not been verified experimentally.	6.38777e-26
NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase	gnl|CDD|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.09381e-97
NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.6734e-12
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.97178e-20
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.54325e-13
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.56161e-106
NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC	gnl|CDD|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	7.73943e-38
NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB	gnl|CDD|99905	cd05563, PTS_IIB_ascorbate, PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a transmembrane channel IIC subunit. Subunits IIA, IIB, and IIC are encoded by the sgaA, sgaB, and sgaT genes of the E. coli sgaTBA operon. In some bacteria, the IIB (SgaB) domain is fused C-terminal to the IIA (SgaT) domain. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include ascorbate, chitobiose/lichenan, lactose, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	8.26522e-29

Protein sequences

>NC_017297.1|WP_012100144.1|2358746_2359268_+|DUF4825-domain-containing-protein
MKNKLKILIPLIIILSLNLVGCGMNSEKKSKENIKNSSKVETYDLIKYKGTYVGDNSSVGSIIKNLPANKYSAGFSLQTSKEPYEITVNYKANENLGEENYNKFWSDKKADKLLEKNAVVLLSLIPNAEIIKFNVDNIGEESYKYDRKNLEQKYGNLKDLSKDNDSLKKFLNN
>NC_017297.1|WP_012100142.1|2356807_2357548_-|class-I-SAM-dependent-methyltransferase
MINYYGSLCTVMYELLHPHAPEDELQFYLQYAKKEMKILEPLCGSGRFLVPFLERGFNITGFDMSEEMLKELYKKAPKAKVFQSSIEKFSPKEKYDYIFITSGSFSLFLDEDIAFNVLVKMKEALAPKGKFVFAAETTANIIHDREKYLKNCAVKTKEGYDIIFKSKSFYDKHKKILSTPSLYELYDGDKLLGKEEMDFRIKLYDFGELDKLILKAGFKGSHVFSDFNRRESIDKNTETFLYECYI
>NC_017297.1|WP_012100141.1|2355312_2356704_+|peptide-MFS-transporter
MSEKKQKHPIGLWLVNISIALQSYAAYAVVSILILFLTADVSKNGLGLSVPKAAAIIGLYQGINYMGSLVGGYITDKWLGIQKSLILGCFLTACGYLALFFAKPNIGSVWLGLIILIVAGAFFKAQISSLVGELYGKNELSKKDAAYSIFYMFINIGAFFGPIIAGLISDKWFAKVAADGEIAAYGYKYIFLMCTLIMIFIGIFIWIVSPKWLGEIGKYPVSKDKKTSTKSIEKAKAQPLTQLEKNRIKAMIVMFVFVIIFWSAWDQTATSFSLLANKLVNRTIGEFTMPVPWLTSINAIFCVVLSPIIANIWLKLGNSKKGDLSVPTKMGLGMILTGIAFLTLILGISTLGGVLDGSKQMNILFIIVAYFLLTVGELCLSPIGMAMFNKLAPAKYGSLAMGAWYLSFFFSSIISGKLAGFTDTLGYTQIFGLISGIVIVFGVILILLRNGLLKLMSLDELDK
>NC_017297.1|WP_012100140.1|2353707_2354322_-|sugar-O-acetyltransferase
MNQKDRMLAGLPYKACLDGLPEERMENKKKIYEYNHCFPDEHEKIHKLIRDILRKAGADVHIEAPFYCDYGKNIQVGDNFFANYNCTILDVGKVIIGNNVQFAPNVSLYTAGHPIHPDSRNSGYEYGIGITIGDNVWLGGNVVVNPGVHIGNNVVIGSGSVVTKDIPDNVIAIGNPCKIIREITEKDRKYYYKNYEFDIDDYKE
>NC_017297.1|WP_012100139.1|2353170_2353665_-|hypothetical-protein
MILAIECFIACVLFTLMILPSLYKEPIKHIMSYPTDIRKRVENLPQYKDVIQKKEKKHLTVKIIAVFMFAIIFAVVAYFSGAKSFSKAYIHVFTLFFVVNIYDMIVLDIGLFCHSKKTRIPGTEDMDKEYRNPWHHIKGAGIGTIIGAVVALLSRGMVHFISII
>NC_017297.1|WP_012100137.1|2350567_2351302_-|hypothetical-protein
MDKFRNMKKSHIALLAVMYIVLMGSLPRFTGWATIFSAIVVGGYFLKNKKDLKELTRKKKNFIFTGIIILAIIGSLNVAVGNNIQNEKLMAEKAKQEQEIKQEEQKKIEEKKLAEEQKRIQEEEAKKKAAEEKRKQEEEAKKKAAEEQKKQEELKRKQEEENKVKAENEQAQAAFAQSTGKGNSNSQSNESQNADDNQNYTVYKTRTGSKYHSSGCRYLKKSCYETTVSQARNEDLTPCSVCNP
>NC_017297.1|WP_012100136.1|2349825_2350230_-|membrane-protein
MNILISTCNIGIPVLMIFIGILYKCNSYKKIDKTLDLIVPIAMFFTGFSERDREHLYKNTNNLASVNRKCSLIWSISGVCTLLLTIISLILNKSDIYNTSVILLEPELLILVIVFITVEYILKRNFNKKISEQY
>NC_017297.1|WP_012100135.1|2348874_2349591_-|transaldolase
MKYNDLKIKIFADGADLNGMLDAYDKGIVKGFTTNPSLMKKAGITDYKEFAKEVLAKIKDMPVSFEVFSDDLETMEKEAEVLGNLGENVYIKIPVTNTKGESTAPLIKKLSEKGYHLNVTAIFTIDQVKEVVGALKSGVDSIVSVFAGRIADTGEDPVTIMKEASKICKTKEGVELLWASCREFYSIVEADKCGCEIITVTNDILKKMPNMGKDLKEYSIETVRGFYKDASSLGFSIL
>NC_017297.1|WP_012100134.1|2348413_2348851_-|PTS-maltose-transporter-subunit-IIBC
MLKNYINDQVVEVNVEVKNWEEAVRLGGKLLEEDGAVEHSYIDAMVDTVKNMGPYIVIAPGIAMPHARPEAGAKNIRIGLLKLKNPINFGNEEHDPVDIVIFLCAVDNKAHIEVLGELVQLIEDDDFLKIVRNASTKKEILDYIK
>NC_017297.1|WP_014519318.1|2348094_2348385_-|PTS-sugar-transporter-subunit-IIB
MNILTVCGNGIGSSLMLAMKIEEICKENGIAANVESTDFNSAQGKKADLIVTVKELAEQFEGRDVAVVRSYINKKKITEDVLEIIKQKDEELKNRS
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND
>NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYKDKETIYIKAISPIHAGSGQSLTSVDMPIQRESHSNIPKIEGSSLKGSVKHNVYHKLRVNKDNKKEEHKLFEKMFGSEDGNDCASAISITDAKLLLFPMRSAIDIYKLITCPYVLKRWKEETNQSFEDSILENIEDGHCVINQNSPLLSNDKVMLEEYIFEARKEDLSILFNGSFENLQINKVVILSDSDFIDMVTMYTEVITRNKINVETGTAQGTGLFSEEYLPAETVMYFSVLESAFYKGEEEVLKYFNENIGGIFQVGGNETIGKGIVKVINHDLLKGVTE
>NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein
MEHKNVEHLVIFSTLNQITNYIAIKNLKPKNIYNITFDQGFADTLKQGIDPKKWDDNLKNVLNDENIKPKRKNIEIKQCMYIDLEKFKEELEKNIEYVDEDTPIYWHITGGQRIFAIAIHDIVKKRPNDIIFYLEGNSEKIIYIGKEKTKFEYELKDLDFSTAFKLMGYNTEDLDSTRILKGKIKKNDKNEKLKYDKNEMKFYHRLYDWIINNDGEKTKSHIAFSIGDKKFEGTFKKLLLESNSINRTIRQEFLKKLFEELEKKSPSLKKIEYNFINSDEMKMEFPAGYIFEKLTGYQIYKVVEDNTRILGMAMSLKVYNEEGGHSTDELDIALLTNTGRIINFECKSGSLKGDNAKSHKFTTYSLSGVFGAPIFLTPLTYKGEKLEKELDKKLHSACKAADRANLEKIYLKDIKEKVKKLIG
>NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3
MKFLKIKPYDNTFFRLGNNFEFKISNVIQTKNVAYPSTFFGAIFTAILANNDEFRESFLNIPGNTDHLEILNIKQIYLYAEKQGMIYIKAPKDIFVNNNEVKFGNFKEIKDGESSIKYDYYLEEPDGNELERADNYFVSIKEFYDKYRYKVLDNIDLKQEDEIFAKNIKTGIALDKSTGIVKESLLYTIEQTEFKNITEDYYSNDWSFVVEYAIDNDFLKKQGYPKVKNLDKGELKLGGETKVCTYEIIENSDINEFKSKTSQGFLKPGEKLKVILTSDSYFTKSFAELFNDEMKILALVNDKPIYIGGFDVAKNEEKAMYKGYSAGTVLLLQNESGKDINLQKYLDMKLRNKLKNGFNEYICVKGE
>NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSYLLGVTVGPIQTNIQKSRKLRELYNSSKIVSDMMKKVIEYLKIRDETLKIIYPSIKDVNDTKTDITNYLICEINNIDDLKDMRERVFDELKISVLEEIYFMFWAVEPLEEYSKTYKKLTKKLRSIKNTYEFKNYEKDVRIKKKCSLCGERIREDASELCEVCNRKRNYDQTSNWKNNNKGEKYKSVYDISIDAWKEKYNEDLLSLNKNLEDLFNNTSRYYSLDTVSNIIKCLKIDPKKVRKEKEIDEDLENPKMEALELIAELKNIRFELESIYLRGEKPVSKPHYKYCFIQIDVDDLGKWISGVYNYEEENLKENQIQISKALCSFAYKLKEEFKNSKTKVIYAGGDDFLAVLPVECLLNTLKIIEEIFKSTVQNNIDNSLNYSQKISYSASVTIANCKDEMSLALRKNREALEKVKNRYYSKNGICINYIINTSKIINMFLLKDYFNEYVDNLRYFKKVEKYMSFTYIDAIENEFSKMKFEDLETDDFLNIKDMLLLEFERHLNLNKNKVPKDSEEGNENFLEYFKIHTRLFENIINDNEIDKKIDFINIINCFRIYKKLTDFQFKEEAKWDEVSKN
>NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MERVKVTLGVVTDMFSEGVNSNKEAEFRITELKALLRSTFREFFYYTSLDDLKEKEELLFGSTNRKSPVIIKFGRNNKIRFKDKKKLVLHKNMFKEAIPSGTTINIIFQSRYEKYLKTYVYTLKLASIMGALGKRSRKGMGAFKIIKIDDNEIIDINKSVEDLLCGYEEQFKINEKIYLIKTRKLLKEKQYKDNCTKYKIECDANMPKNVNYVKNIYKIYLGNLTEEKSRNKIDCTLRNFSWLNHYRLSDLNKIFSNETIKKIEKETGKRIDNEISLENLFNKEILGNYNYKYKEKEVTKKNILTRFACPVYVTIYQKSRGELIENYLIIKELNYDYVYKKILDKKVSNKKVTEQKKEEIRTDIKSELKEMKPIDKYYVEEFVKKIIECCEVK
>NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6
MEFWELIVTAMLKKDIYFEDCGYIIGKNINKSMLWDKDLKEVHPKKQYKNYVFNSFYPIERDKFYKKDRLYIFNIRGLSKEFIDKIETCLCNLESNDFNVISTSKKEIKQRYIKELYTQTPLIITVDDKPWLQNDGDLDLFKQRLEDNLEKKYKSFFNEDIDVKGKFIKSIEFKNRKPMHYNYKNGKKLLANKVSIQIEDNEEAQKVAFLARAIGLGEKNPSIGAGFCK

Crispr_ID: NC_017297_11

• CRISPR_ID: NC_017297_11
• CRISPR_location: 2374002-2374313
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 4 spacers
• Cas_protein_info: cas6,cmr1gr7,cas10,cmr3gr5,csx1,cmr4gr7,cmr5gr11,cmr6gr7

Consensus repeat of NC_017297_11

Consensus_repeat	Method
ATTTAAATACATCTCATGTTAATGTT	CRISPRCasFinder

spacers of NC_017297_11

>11.1|2374028|62|NC_017297|CRISPRCasFinder
TAATATATTATGTTATTGCATTCAACAACAGTTTGATATCAGTCCCCTTATGGGACGTGCAA
>11.2|2374116|41|NC_017297|CRISPRCasFinder
CAACGACTTAGTGAATTTGAAGGATCTGGCAGAGAATTTGG
>11.3|2374183|40|NC_017297|CRISPRCasFinder
CAACCCCGGGGGTGTATAAGATATTCTTTTTCCTTATTTG
>11.4|2374249|39|NC_017297|CRISPRCasFinder
CAACGGTATTTCTTGATTAGTTGCAAGTATATTTTCCCA

CRISPR arrays and Neighbor proteins around NC_017297_11

CRISPR arrays

The CRISPR arrays of NC_017297_11

>merge|NC_017297|11|2374002-2374313|CRISPRCasFinder
TTCTTATTATATATCATATTAATTTTTAATATATTATGTTATTGCATTCAACAACAGTTTGATATCAGTCCCCTTATGGGACGTGCAAATTTAAATATATCTTATATTAATGTTCAACGACTTAGTGAATTTGAAGGATCTGGCAGAGAATTTGGATTTAAATACATCTCATGTTAATGTTCAACCCCGGGGGTGTATAAGATATTCTTTTTCCTTATTTGATTTAAATACATCTCATGTTAATGTTCAACGGTATTTCTTGATTAGTTGCAAGTATATTTTCCCAATTTAAATACATATCATGTTAATGTT

>NC_017297|11|11|2374002-2374313|CRISPRCasFinder
TTCTTATTATATATCATATTAATTTT	TAATATATTATGTTATTGCATTCAACAACAGTTTGATATCAGTCCCCTTATGGGACGTGCAA
ATTTAAATATATCTTATATTAATGTT	CAACGACTTAGTGAATTTGAAGGATCTGGCAGAGAATTTGG
ATTTAAATACATCTCATGTTAATGTT	CAACCCCGGGGGTGTATAAGATATTCTTTTTCCTTATTTG
ATTTAAATACATCTCATGTTAATGTT	CAACGGTATTTCTTGATTAGTTGCAAGTATATTTTCCCA
ATTTAAATACATATCATGTTAATGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase	unknown	unknown	gnl|CDD|224835
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	unknown
NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	unknown	unknown	gnl|CDD|319898
NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461
NC_017297.1|WP_012100163.1|2382320_2382542_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_017297.1|WP_012100166.1|2385349_2386249_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein	unknown	unknown	gnl|CDD|270622
NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease	unknown	unknown	gnl|CDD|223605
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein	unknown	unknown	gnl|CDD|226458
NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.3e-66	219.0	0.1
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	2.1e-37	123.7	34.8
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	9.3e-18	59.1	22.6
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	9.5e-154	507.1	32.1
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	2.8e-81	268.4	0.0
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	2e-27	91.5	8.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.35159e-25
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase	gnl|CDD|224835	COG1924, COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism].	3.25004e-98
NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.39603e-61
NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	gnl|CDD|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	3.53317e-15
NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	8.56122e-90
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.56161e-106
NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	9.62275e-27
NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein	gnl|CDD|270622	cd00180, PKc, Catalytic domain of Protein Kinases. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. PKs make up a large family of serine/threonine kinases (STKs), protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and more than 500 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase.	4.85601e-23
NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.70987e-116
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.54325e-13
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.18416e-65
NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein	gnl|CDD|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	4.00855e-33
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.97178e-20

Protein sequences

>NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6
MEFWELIVTAMLKKDIYFEDCGYIIGKNINKSMLWDKDLKEVHPKKQYKNYVFNSFYPIERDKFYKKDRLYIFNIRGLSKEFIDKIETCLCNLESNDFNVISTSKKEIKQRYIKELYTQTPLIITVDDKPWLQNDGDLDLFKQRLEDNLEKKYKSFFNEDIDVKGKFIKSIEFKNRKPMHYNYKNGKKLLANKVSIQIEDNEEAQKVAFLARAIGLGEKNPSIGAGFCK
>NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MERVKVTLGVVTDMFSEGVNSNKEAEFRITELKALLRSTFREFFYYTSLDDLKEKEELLFGSTNRKSPVIIKFGRNNKIRFKDKKKLVLHKNMFKEAIPSGTTINIIFQSRYEKYLKTYVYTLKLASIMGALGKRSRKGMGAFKIIKIDDNEIIDINKSVEDLLCGYEEQFKINEKIYLIKTRKLLKEKQYKDNCTKYKIECDANMPKNVNYVKNIYKIYLGNLTEEKSRNKIDCTLRNFSWLNHYRLSDLNKIFSNETIKKIEKETGKRIDNEISLENLFNKEILGNYNYKYKEKEVTKKNILTRFACPVYVTIYQKSRGELIENYLIIKELNYDYVYKKILDKKVSNKKVTEQKKEEIRTDIKSELKEMKPIDKYYVEEFVKKIIECCEVK
>NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSYLLGVTVGPIQTNIQKSRKLRELYNSSKIVSDMMKKVIEYLKIRDETLKIIYPSIKDVNDTKTDITNYLICEINNIDDLKDMRERVFDELKISVLEEIYFMFWAVEPLEEYSKTYKKLTKKLRSIKNTYEFKNYEKDVRIKKKCSLCGERIREDASELCEVCNRKRNYDQTSNWKNNNKGEKYKSVYDISIDAWKEKYNEDLLSLNKNLEDLFNNTSRYYSLDTVSNIIKCLKIDPKKVRKEKEIDEDLENPKMEALELIAELKNIRFELESIYLRGEKPVSKPHYKYCFIQIDVDDLGKWISGVYNYEEENLKENQIQISKALCSFAYKLKEEFKNSKTKVIYAGGDDFLAVLPVECLLNTLKIIEEIFKSTVQNNIDNSLNYSQKISYSASVTIANCKDEMSLALRKNREALEKVKNRYYSKNGICINYIINTSKIINMFLLKDYFNEYVDNLRYFKKVEKYMSFTYIDAIENEFSKMKFEDLETDDFLNIKDMLLLEFERHLNLNKNKVPKDSEEGNENFLEYFKIHTRLFENIINDNEIDKKIDFINIINCFRIYKKLTDFQFKEEAKWDEVSKN
>NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3
MKFLKIKPYDNTFFRLGNNFEFKISNVIQTKNVAYPSTFFGAIFTAILANNDEFRESFLNIPGNTDHLEILNIKQIYLYAEKQGMIYIKAPKDIFVNNNEVKFGNFKEIKDGESSIKYDYYLEEPDGNELERADNYFVSIKEFYDKYRYKVLDNIDLKQEDEIFAKNIKTGIALDKSTGIVKESLLYTIEQTEFKNITEDYYSNDWSFVVEYAIDNDFLKKQGYPKVKNLDKGELKLGGETKVCTYEIIENSDINEFKSKTSQGFLKPGEKLKVILTSDSYFTKSFAELFNDEMKILALVNDKPIYIGGFDVAKNEEKAMYKGYSAGTVLLLQNESGKDINLQKYLDMKLRNKLKNGFNEYICVKGE
>NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein
MEHKNVEHLVIFSTLNQITNYIAIKNLKPKNIYNITFDQGFADTLKQGIDPKKWDDNLKNVLNDENIKPKRKNIEIKQCMYIDLEKFKEELEKNIEYVDEDTPIYWHITGGQRIFAIAIHDIVKKRPNDIIFYLEGNSEKIIYIGKEKTKFEYELKDLDFSTAFKLMGYNTEDLDSTRILKGKIKKNDKNEKLKYDKNEMKFYHRLYDWIINNDGEKTKSHIAFSIGDKKFEGTFKKLLLESNSINRTIRQEFLKKLFEELEKKSPSLKKIEYNFINSDEMKMEFPAGYIFEKLTGYQIYKVVEDNTRILGMAMSLKVYNEEGGHSTDELDIALLTNTGRIINFECKSGSLKGDNAKSHKFTTYSLSGVFGAPIFLTPLTYKGEKLEKELDKKLHSACKAADRANLEKIYLKDIKEKVKKLIG
>NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYKDKETIYIKAISPIHAGSGQSLTSVDMPIQRESHSNIPKIEGSSLKGSVKHNVYHKLRVNKDNKKEEHKLFEKMFGSEDGNDCASAISITDAKLLLFPMRSAIDIYKLITCPYVLKRWKEETNQSFEDSILENIEDGHCVINQNSPLLSNDKVMLEEYIFEARKEDLSILFNGSFENLQINKVVILSDSDFIDMVTMYTEVITRNKINVETGTAQGTGLFSEEYLPAETVMYFSVLESAFYKGEEEVLKYFNENIGGIFQVGGNETIGKGIVKVINHDLLKGVTE
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein
MEYFHVDVFSNEILYGNGLTVVFCNEELEDNLMLKLTQEFKQFETIFVRRIDNSIFNARIFTVDEELDFAGHPILGAAATIHSNIFRNEEDIAITFQLNQKTIIVNSKKIEEYYEVQMNQGKAEFLCEVSKEKRNKYVHALNLSEENLSEEFPMEVVSTGLPYLLVPLTSGIENAKIISSKFEEMLKEVGAKFAYIFDVNYIEGRTWDNQGNVEDVATGSAAGPLGAYLYKHNIFNVGHEIIINQGRFVGRPSKIKVSMSISEKEILVSGEVAILAKGTILL
>NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGINKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIDDIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein
MNIKIDKNSIITITQQLVHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLKQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLGLIQNDIKLLSEYPPAQGDYEFRNIMSQYLRSKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIAIYNDILIVEDDPWNEISYKREKIKTIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHSPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein
MNFCWITLNVSNMEESLNFYHKIIGLKISERFNVGEDIEIAMLGETDGTKVELIYNKKQSVLSRSEGLSIGFEVKLLDEAMELLKNKNIPIKRGPISPLPSSRFFFIDDPNGIEIQIVQHN
>NC_017297.1|WP_012100163.1|2382320_2382542_-|hypothetical-protein
MNQGQEKFLGFILERVEEDKVEEAKALLADNFKKQAEGNFTTQFIPKMAMLLKPDKIEEVQTVMKQFAENFSH
>NC_017297.1|WP_012100166.1|2385349_2386249_+|hypothetical-protein
MSNKRNLQSLRSFYICILIFNMVSNSIFHLNNNGFNIKLFKNFTIRSVILLDLNILLFLIIVIAFEKKINIDEEANTQLNTRIRPLYLVNIFFIAYILVCIFLLKDIDVILSSFIMEIIYIGIIILSKKIITLELTNRQLQWQKACGYIDEDCEESSFLWRFKLWWSPHVNVPFKNRWKGSSRLLYDLALVYGIIISKGNLFSLILLILLLPDVISWLEGLLGLQTSLTGICTGITEHHSKNSHVLYHKVYVTDYKNKREITFYVDGPLFIHENSHMTVVHGTFSKRVLYVEGLNLDIR
>NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGMLSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVPLMIIAIFGIFQGVNNGILIENFSKVSIISDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVIIYILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTIFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPDAFSKLNSKTNIPTNSTIANFILICIYLVVWYMNFKGLFPNKMFVDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSLALMGALIVVYGGLSKPSVIIDLGISVFVFLSGLLFYNKKK
>NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein
MVIKFLKRDTKYLPEQKIHEYTVLKVLGEGRFGICYLVQSNNKQYILKQLKTKMLKKVGSKVIYEQEILKNINHNCIPKFVKTLQFEKIFGYVLKYKEGKTFEEIICEDEYVFKREEIYDICIQIIEILKYLHKNGIVHRDIRIPNTIYYKKKVNLVDFGLARWINNKRYTENVDFSYLGDFLLHLYYTSFQCKTFKGKPWYEELDLFSEEMNFLKRLLGIEKKYKNIEEVERDFLLLKSNYNK
>NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase
MYTMGLDIGSTTSKGVIMKDGKEIVASVLVPVGTGTSGPLKLIKELKEKSNLTEKDIEKTVVTGYGRIQYKDADKQISELSCHAKGVAFLIPGARTIIDIGGQDAKAMKLNDKGKLINFIMNDKCAAGTGRFLDVMAGVLETDVSKLGEISEKSTKEVSISSTCTVFAESEVISHLSANAKKEDIIAGIHTSVVRRVSTLAMRVGIEDQVVMVGGVARNKGIVKAMEKELGHDIKVPELAQLTGALGAAIYAFEETK
>NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein
MSENSKSKVGFLTAFQVAAVWFGAHVGGGFATGNQTMNFFVKHGWHSIWLPAVIIIIIGLTYKESLILAKNYGTYDYKSWSKKMYEPYDKVFSFIFEIGYLMIVLLGTGGSIAGSASLMETYGVNYLVGVLITGGIFYILTIYGSELIRKASTIITVLILIFLTIIVIVGIVNNSGNLSHLVSTKYSPSSFGTVLYSGLRYAGYQAFVVAIVLSASDTLKSDKAINKSILLGVILNGAMITLSCIMLLAWMPGAQKETIPILYICKRLNDGFLLFSYSVVLFLAFVSTGIGCVFGAVARFEHVFKKPENIKKRRGLISLVCMILSMAISLFGLTKIVVIGYGYVGIIGIFVVVIPCIVVGRIKNNKFKKEQQSILIENKDDTSSKEDNDNVLIGDQDDMLEENKDSILQDQDDISKEDEENMPVEEQDDASKENKESVSVEDQVDVLKGEQDSVPEGEDDTLKEDGENAPVEGQDDASKGNKKSVLVEGQDDMPKEDKESASIEEQKSTSTQEDGNASKEE

Crispr_ID: NC_017297_12

• CRISPR_ID: NC_017297_12
• CRISPR_location: 2376525-2376617
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 1 spacers
• Cas_protein_info: cas6,cmr1gr7,cas10,cmr3gr5,csx1,cmr4gr7,cmr5gr11,cmr6gr7

Consensus repeat of NC_017297_12

Consensus_repeat	Method
TTAAATACATCTTATGTTAATGTTCAA	CRISPRCasFinder

spacers of NC_017297_12

>12.1|2376552|39|NC_017297|CRISPRCasFinder
TTATTGCCTATATGATAGACGAAGATTATAGATTCTTAT

CRISPR arrays and Neighbor proteins around NC_017297_12

CRISPR arrays

The CRISPR arrays of NC_017297_12

>merge|NC_017297|12|2376525-2376617|CRISPRCasFinder
TTAAATACATCTTATGTTAATGTTCAATTATTGCCTATATGATAGACGAAGATTATAGATTCTTATTTAAATACATCCTATGTTAATGTTCAA

>NC_017297|12|12|2376525-2376617|CRISPRCasFinder
TTAAATACATCTTATGTTAATGTTCAA	TTATTGCCTATATGATAGACGAAGATTATAGATTCTTAT
TTAAATACATCCTATGTTAATGTTCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase	unknown	unknown	gnl|CDD|224835
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	unknown
NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	unknown	unknown	gnl|CDD|319898
NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461
NC_017297.1|WP_012100163.1|2382320_2382542_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_017297.1|WP_012100166.1|2385349_2386249_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein	unknown	unknown	gnl|CDD|270622
NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	gnl|CDD|187880
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease	unknown	unknown	gnl|CDD|223605
NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl|CDD|224255
NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein	unknown	unknown	gnl|CDD|226458
NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	2.3e-66	219.0	0.1
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	2.1e-37	123.7	34.8
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	3.9e-42	139.3	4.5
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	9.3e-18	59.1	22.6
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	9.5e-154	507.1	32.1
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	pfam09701_cmr5gr11_CAS-III-B	9.1e-44	143.5	3.1
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	2.8e-81	268.4	0.0
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	2e-27	91.5	8.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.35159e-25
NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	4.57115e-34
NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase	gnl|CDD|224835	COG1924, COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism].	3.25004e-98
NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.39603e-61
NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	gnl|CDD|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	3.53317e-15
NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	8.56122e-90
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.56161e-106
NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	9.62275e-27
NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein	gnl|CDD|270622	cd00180, PKc, Catalytic domain of Protein Kinases. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. PKs make up a large family of serine/threonine kinases (STKs), protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and more than 500 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase.	4.85601e-23
NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.70987e-116
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.54325e-13
NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|187880	cd09749, Cmr5_III-B, CRISPR/Cas system-associated protein Cmr5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-B.	5.93673e-38
NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	4.80213e-15
NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.18416e-65
NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein	gnl|CDD|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	4.00855e-33
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.97178e-20

Protein sequences

>NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6
MEFWELIVTAMLKKDIYFEDCGYIIGKNINKSMLWDKDLKEVHPKKQYKNYVFNSFYPIERDKFYKKDRLYIFNIRGLSKEFIDKIETCLCNLESNDFNVISTSKKEIKQRYIKELYTQTPLIITVDDKPWLQNDGDLDLFKQRLEDNLEKKYKSFFNEDIDVKGKFIKSIEFKNRKPMHYNYKNGKKLLANKVSIQIEDNEEAQKVAFLARAIGLGEKNPSIGAGFCK
>NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MERVKVTLGVVTDMFSEGVNSNKEAEFRITELKALLRSTFREFFYYTSLDDLKEKEELLFGSTNRKSPVIIKFGRNNKIRFKDKKKLVLHKNMFKEAIPSGTTINIIFQSRYEKYLKTYVYTLKLASIMGALGKRSRKGMGAFKIIKIDDNEIIDINKSVEDLLCGYEEQFKINEKIYLIKTRKLLKEKQYKDNCTKYKIECDANMPKNVNYVKNIYKIYLGNLTEEKSRNKIDCTLRNFSWLNHYRLSDLNKIFSNETIKKIEKETGKRIDNEISLENLFNKEILGNYNYKYKEKEVTKKNILTRFACPVYVTIYQKSRGELIENYLIIKELNYDYVYKKILDKKVSNKKVTEQKKEEIRTDIKSELKEMKPIDKYYVEEFVKKIIECCEVK
>NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSYLLGVTVGPIQTNIQKSRKLRELYNSSKIVSDMMKKVIEYLKIRDETLKIIYPSIKDVNDTKTDITNYLICEINNIDDLKDMRERVFDELKISVLEEIYFMFWAVEPLEEYSKTYKKLTKKLRSIKNTYEFKNYEKDVRIKKKCSLCGERIREDASELCEVCNRKRNYDQTSNWKNNNKGEKYKSVYDISIDAWKEKYNEDLLSLNKNLEDLFNNTSRYYSLDTVSNIIKCLKIDPKKVRKEKEIDEDLENPKMEALELIAELKNIRFELESIYLRGEKPVSKPHYKYCFIQIDVDDLGKWISGVYNYEEENLKENQIQISKALCSFAYKLKEEFKNSKTKVIYAGGDDFLAVLPVECLLNTLKIIEEIFKSTVQNNIDNSLNYSQKISYSASVTIANCKDEMSLALRKNREALEKVKNRYYSKNGICINYIINTSKIINMFLLKDYFNEYVDNLRYFKKVEKYMSFTYIDAIENEFSKMKFEDLETDDFLNIKDMLLLEFERHLNLNKNKVPKDSEEGNENFLEYFKIHTRLFENIINDNEIDKKIDFINIINCFRIYKKLTDFQFKEEAKWDEVSKN
>NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3
MKFLKIKPYDNTFFRLGNNFEFKISNVIQTKNVAYPSTFFGAIFTAILANNDEFRESFLNIPGNTDHLEILNIKQIYLYAEKQGMIYIKAPKDIFVNNNEVKFGNFKEIKDGESSIKYDYYLEEPDGNELERADNYFVSIKEFYDKYRYKVLDNIDLKQEDEIFAKNIKTGIALDKSTGIVKESLLYTIEQTEFKNITEDYYSNDWSFVVEYAIDNDFLKKQGYPKVKNLDKGELKLGGETKVCTYEIIENSDINEFKSKTSQGFLKPGEKLKVILTSDSYFTKSFAELFNDEMKILALVNDKPIYIGGFDVAKNEEKAMYKGYSAGTVLLLQNESGKDINLQKYLDMKLRNKLKNGFNEYICVKGE
>NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein
MEHKNVEHLVIFSTLNQITNYIAIKNLKPKNIYNITFDQGFADTLKQGIDPKKWDDNLKNVLNDENIKPKRKNIEIKQCMYIDLEKFKEELEKNIEYVDEDTPIYWHITGGQRIFAIAIHDIVKKRPNDIIFYLEGNSEKIIYIGKEKTKFEYELKDLDFSTAFKLMGYNTEDLDSTRILKGKIKKNDKNEKLKYDKNEMKFYHRLYDWIINNDGEKTKSHIAFSIGDKKFEGTFKKLLLESNSINRTIRQEFLKKLFEELEKKSPSLKKIEYNFINSDEMKMEFPAGYIFEKLTGYQIYKVVEDNTRILGMAMSLKVYNEEGGHSTDELDIALLTNTGRIINFECKSGSLKGDNAKSHKFTTYSLSGVFGAPIFLTPLTYKGEKLEKELDKKLHSACKAADRANLEKIYLKDIKEKVKKLIG
>NC_017297.1|WP_012100152.1|2366914_2367778_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYKDKETIYIKAISPIHAGSGQSLTSVDMPIQRESHSNIPKIEGSSLKGSVKHNVYHKLRVNKDNKKEEHKLFEKMFGSEDGNDCASAISITDAKLLLFPMRSAIDIYKLITCPYVLKRWKEETNQSFEDSILENIEDGHCVINQNSPLLSNDKVMLEEYIFEARKEDLSILFNGSFENLQINKVVILSDSDFIDMVTMYTEVITRNKINVETGTAQGTGLFSEEYLPAETVMYFSVLESAFYKGEEEVLKYFNENIGGIFQVGGNETIGKGIVKVINHDLLKGVTE
>NC_017297.1|WP_012100151.1|2366435_2366915_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGDLKNVNLQVAQFALEKVKEVLNYYEKEILKCKEEEREQIEKKQKMLSSKYKTLSKKMTVLIQKNGLIGTLVFILSKVKKEKANELVLQHIINWCEEDCKLDFLRVDKENTNPNEAFIENITKLSNQEYRLVTKEIMNLFGWIKRFTDGMIEGEVQND
>NC_017297.1|WP_012100150.1|2365144_2366443_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MIKLLKVKSFSTKRGAEFENKETFNKLKQEFYKNPKIGDYVFCSIEEDKLRGLEWRLYQDIDNTNVYEQWQKWKKDSCHYGLKLDKFTNVFNGREESVNKKIDQSIHLNIDDYLKEDKNLYENIDFNVKVFDKLVVGLGEHSVFETDIKLHHTYGVPYIPASAVKGCFRSHIIQKYFQSKEKKAEEDKNFIEIFGGEYKDKTYSGNVIFIDLFPKNSFEIKKDVMTPHYQNGYTDDGNITPIEFLTVENTLFRFILRISNKCLLQDNNSKIKLKENQDVRDLIVEELVEMIATHGIGAKTSVGYGYFEEVTKEECLEQTENNEKRREEEILEAKEKKKLMKMNDSEKKLYLVEKISDCEKRKEGLRKLFTNRKQEELEQTEIEKLAKLIKRDLEDSGKWRYKIGKKGKKNKELERIEKICEILNIDLPKNSN
>NC_017297.1|WP_012100149.1|2364417_2364711_-|hypothetical-protein
MNFFTLNILIGAMAFIINKINNMSQDIDPFEAFNDIEENLDEIDNEKVTNFVNGLINASMSNPSIGYFFMFLVYMTPVLNLLLLIKGIINYFNRAVG
>NC_017297.1|WP_012100148.1|2363571_2364369_-|MerR-family-transcriptional-regulator
MRYSITDLAEILGCTTSAIHYFEKEHLIEVEKGKNGHRYYNVVDVFRLLSYTKYRSMEIPMKTIIAQFGGEENNYKLIEEREAMYQLEALKRAQYYMNLADAIGEHLVSVRRIEELLDKYEFAKSPEVTIMCDDECGWLSKKRSSQRIIHEWVKAMPTVQLGVFDSRMGISNFGYLVKTKKREELELPLGLHTKQLKSTSCIHTIVMADEDFTQHPQKVFKKASEFAIKKGLEIGEIAWGKILLVEVEKGAKLHPYIELWISIKI
>NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein
MEYFHVDVFSNEILYGNGLTVVFCNEELEDNLMLKLTQEFKQFETIFVRRIDNSIFNARIFTVDEELDFAGHPILGAAATIHSNIFRNEEDIAITFQLNQKTIIVNSKKIEEYYEVQMNQGKAEFLCEVSKEKRNKYVHALNLSEENLSEEFPMEVVSTGLPYLLVPLTSGIENAKIISSKFEEMLKEVGAKFAYIFDVNYIEGRTWDNQGNVEDVATGSAAGPLGAYLYKHNIFNVGHEIIINQGRFVGRPSKIKVSMSISEKEILVSGEVAILAKGTILL
>NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGINKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIDDIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein
MNIKIDKNSIITITQQLVHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLKQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLGLIQNDIKLLSEYPPAQGDYEFRNIMSQYLRSKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIAIYNDILIVEDDPWNEISYKREKIKTIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHSPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein
MNFCWITLNVSNMEESLNFYHKIIGLKISERFNVGEDIEIAMLGETDGTKVELIYNKKQSVLSRSEGLSIGFEVKLLDEAMELLKNKNIPIKRGPISPLPSSRFFFIDDPNGIEIQIVQHN
>NC_017297.1|WP_012100163.1|2382320_2382542_-|hypothetical-protein
MNQGQEKFLGFILERVEEDKVEEAKALLADNFKKQAEGNFTTQFIPKMAMLLKPDKIEEVQTVMKQFAENFSH
>NC_017297.1|WP_012100166.1|2385349_2386249_+|hypothetical-protein
MSNKRNLQSLRSFYICILIFNMVSNSIFHLNNNGFNIKLFKNFTIRSVILLDLNILLFLIIVIAFEKKINIDEEANTQLNTRIRPLYLVNIFFIAYILVCIFLLKDIDVILSSFIMEIIYIGIIILSKKIITLELTNRQLQWQKACGYIDEDCEESSFLWRFKLWWSPHVNVPFKNRWKGSSRLLYDLALVYGIIISKGNLFSLILLILLLPDVISWLEGLLGLQTSLTGICTGITEHHSKNSHVLYHKVYVTDYKNKREITFYVDGPLFIHENSHMTVVHGTFSKRVLYVEGLNLDIR
>NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGMLSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVPLMIIAIFGIFQGVNNGILIENFSKVSIISDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVIIYILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTIFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPDAFSKLNSKTNIPTNSTIANFILICIYLVVWYMNFKGLFPNKMFVDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSLALMGALIVVYGGLSKPSVIIDLGISVFVFLSGLLFYNKKK
>NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein
MVIKFLKRDTKYLPEQKIHEYTVLKVLGEGRFGICYLVQSNNKQYILKQLKTKMLKKVGSKVIYEQEILKNINHNCIPKFVKTLQFEKIFGYVLKYKEGKTFEEIICEDEYVFKREEIYDICIQIIEILKYLHKNGIVHRDIRIPNTIYYKKKVNLVDFGLARWINNKRYTENVDFSYLGDFLLHLYYTSFQCKTFKGKPWYEELDLFSEEMNFLKRLLGIEKKYKNIEEVERDFLLLKSNYNK
>NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase
MYTMGLDIGSTTSKGVIMKDGKEIVASVLVPVGTGTSGPLKLIKELKEKSNLTEKDIEKTVVTGYGRIQYKDADKQISELSCHAKGVAFLIPGARTIIDIGGQDAKAMKLNDKGKLINFIMNDKCAAGTGRFLDVMAGVLETDVSKLGEISEKSTKEVSISSTCTVFAESEVISHLSANAKKEDIIAGIHTSVVRRVSTLAMRVGIEDQVVMVGGVARNKGIVKAMEKELGHDIKVPELAQLTGALGAAIYAFEETK
>NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein
MSENSKSKVGFLTAFQVAAVWFGAHVGGGFATGNQTMNFFVKHGWHSIWLPAVIIIIIGLTYKESLILAKNYGTYDYKSWSKKMYEPYDKVFSFIFEIGYLMIVLLGTGGSIAGSASLMETYGVNYLVGVLITGGIFYILTIYGSELIRKASTIITVLILIFLTIIVIVGIVNNSGNLSHLVSTKYSPSSFGTVLYSGLRYAGYQAFVVAIVLSASDTLKSDKAINKSILLGVILNGAMITLSCIMLLAWMPGAQKETIPILYICKRLNDGFLLFSYSVVLFLAFVSTGIGCVFGAVARFEHVFKKPENIKKRRGLISLVCMILSMAISLFGLTKIVVIGYGYVGIIGIFVVVIPCIVVGRIKNNKFKKEQQSILIENKDDTSSKEDNDNVLIGDQDDMLEENKDSILQDQDDISKEDEENMPVEEQDDASKENKESVSVEDQVDVLKGEQDSVPEGEDDTLKEDGENAPVEGQDDASKGNKKSVLVEGQDDMPKEDKESASIEEQKSTSTQEDGNASKEE

Crispr_ID: NC_017297_13

• CRISPR_ID: NC_017297_13
• CRISPR_location: 2382754-2382851
• CRISPR_type: TypeIII
• Repeat_type: III-B
• Spacer_info: 1 spacers
• Cas_protein_info: cas6,cmr1gr7,cas10,cmr3gr5,csx1

Consensus repeat of NC_017297_13

Consensus_repeat	Method
CAAATTTAAATACATCTTATGTTAATGTTCAAC	CRISPRCasFinder

spacers of NC_017297_13

>13.1|2382787|32|NC_017297|CRISPRCasFinder
TAATTATCATTATAAAAACCCTCATCCATATG

CRISPR arrays and Neighbor proteins around NC_017297_13

CRISPR arrays

The CRISPR arrays of NC_017297_13

>merge|NC_017297|13|2382754-2382851|CRISPRCasFinder
CAAATTTAAATACATCTTATGTTAATGTTCAACTAATTATCATTATAAAAACCCTCATCCATATGCAAATTTAAATACATCTTATGTTAATGTTCAAC

>NC_017297|13|13|2382754-2382851|CRISPRCasFinder
CAAATTTAAATACATCTTATGTTAATGTTCAAC	TAATTATCATTATAAAAACCCTCATCCATATG
CAAATTTAAATACATCTTATGTTAATGTTCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_004451550.1|2395470_2396598_-|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl|CDD|377594
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase	unknown	unknown	gnl|CDD|224835
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	unknown
NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	unknown	unknown	gnl|CDD|319898
NC_017297.1|WP_003358160.1|2396597_2397830_-|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl|CDD|377594
NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461
NC_017297.1|WP_012100163.1|2382320_2382542_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100172.1|2393015_2393801_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	unknown	unknown	gnl|CDD|224997
NC_017297.1|WP_012100166.1|2385349_2386249_+|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein	unknown	unknown	gnl|CDD|270622
NC_017297.1|WP_012100173.1|2393839_2394973_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_017297.1|WP_004451547.1|2391947_2392997_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl|CDD|224936
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease	unknown	unknown	gnl|CDD|223605
NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein	unknown	unknown	gnl|CDD|226458
NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl|CDD|223461

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein	csx1	mkCas0085_csx1_CAS-III	9.5e-154	507.1	32.1
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	2.1e-37	123.7	34.8
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	9.3e-18	59.1	22.6
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	2.8e-81	268.4	0.0
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	2e-27	91.5	8.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_004451550.1|2395470_2396598_-|2-hydroxyacyl-CoA-dehydratase	gnl|CDD|377594	pfam06050, HGD-D, 2-hydroxyglutaryl-CoA dehydratase, D-component. Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic process is catalyzed by 2-hydroxyglutaryl-CoA dehydratase, an enzyme with two components (A and D) that reversibly associate during reaction cycles. This component contains one non-reducible [4Fe-4S]2+ cluster and a reduced riboflavin 5'-monophosphate.	1.07678e-101
NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.35159e-25
NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.70987e-116
NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase	gnl|CDD|224835	COG1924, COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism].	3.25004e-98
NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	3.39603e-61
NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	gnl|CDD|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	3.53317e-15
NC_017297.1|WP_003358160.1|2396597_2397830_-|2-hydroxyacyl-CoA-dehydratase	gnl|CDD|377594	pfam06050, HGD-D, 2-hydroxyglutaryl-CoA dehydratase, D-component. Degradation of glutamate via the hydroxyglutarate pathway involves the syn-elimination of water from 2-hydroxyglutaryl-CoA. This anaerobic process is catalyzed by 2-hydroxyglutaryl-CoA dehydratase, an enzyme with two components (A and D) that reversibly associate during reaction cycles. This component contains one non-reducible [4Fe-4S]2+ cluster and a reduced riboflavin 5'-monophosphate.	1.98293e-71
NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	9.62275e-27
NC_017297.1|WP_012100172.1|2393015_2393801_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein	gnl|CDD|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	7.85324e-97
NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.56161e-106
NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein	gnl|CDD|270622	cd00180, PKc, Catalytic domain of Protein Kinases. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. PKs make up a large family of serine/threonine kinases (STKs), protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and more than 500 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase.	4.85601e-23
NC_017297.1|WP_012100173.1|2393839_2394973_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	4.54325e-13
NC_017297.1|WP_004451547.1|2391947_2392997_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl|CDD|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.34231e-134
NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein	gnl|CDD|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	8.56122e-90
NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein	gnl|CDD|226458	COG3949, COG3949, Uncharacterized membrane protein [Function unknown].	4.00855e-33
NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.97178e-20

Protein sequences

>NC_017297.1|WP_012100163.1|2382320_2382542_-|hypothetical-protein
MNQGQEKFLGFILERVEEDKVEEAKALLADNFKKQAEGNFTTQFIPKMAMLLKPDKIEEVQTVMKQFAENFSH
>NC_017297.1|WP_012100162.1|2381831_2382197_-|glyoxalase/bleomycin-resistance/dioxygenase-family-protein
MNFCWITLNVSNMEESLNFYHKIIGLKISERFNVGEDIEIAMLGETDGTKVELIYNKKQSVLSRSEGLSIGFEVKLLDEAMELLKNKNIPIKRGPISPLPSSRFFFIDDPNGIEIQIVQHN
>NC_017297.1|WP_012100161.1|2379266_2380760_+|PLP-dependent-aminotransferase-family-protein
MNIKIDKNSIITITQQLVHYFSDRIMSGFIKAGQKLPSIRSLAKELGISPMTIIKAYNNLKQNGLVTTIQGKGTYVNERNSTVKSNNITEKDSFQWQMSVPDYLSRSQFRYNPNLSYSNDYYNLSVASLNHKLLPTKTILKDSLGLIQNDIKLLSEYPPAQGDYEFRNIMSQYLRSKEIATSPENILVTSGSQQGISLIASTFIGPGDIVVMETPTYPGAIDLFKCRGAVILTVPVDSEGMRTDILMNLCDKHSPKLIYTIPNFHNPTGYSMSSKRKAELLDIAIYNDILIVEDDPWNEISYKREKIKTIKSMDTDGHVVYIKSLSKILGPSYRLAVIISESSILSRLIAAKANHDLGTSVLIQKTIINFIQSNKITYYIESLNKQLVKRRDKVISLLKSHSPSGMKWAIPEGGINIWVTLPKNFNVEKLLSYSITTKNISFLPGTICYPNEVEFNNLRICFTYLDEEFIEDTIIELCNLIKLLYTTKNITDYRPII
>NC_017297.1|WP_012100160.1|2378021_2378942_-|PhzF-family-phenazine-biosynthesis-protein
MRKFEYTLVDVFTNQVFGGNQLAVFKDAEKLSSEEMQSIARELNFSETTFVTDIGPNHKKLRIFTPKTELPMAGHPTIGTAFVLADEGAVETREGINKLIFEEGVGEIAVSIHVEGGRIRSIEMEQPMPVFGQVFGDIRTAAELLSLDIDDIDTTSPIQTVSTGVPFLYIPLKSLDVISKIKLRLDTWEKFFSASEDTKHIFAFTRETLHAGSTIHSRMFAPAMGIAEDPATGGASGPLGAYLVEHGLVAHGYDGKYMIINEQGIEMGRPSFINITVSKTYNNFSEIKIGGTCVKFGAGLIELPTL
>NC_017297.1|WP_004451526.1|2376882_2377731_-|PhzF-family-phenazine-biosynthesis-protein
MEYFHVDVFSNEILYGNGLTVVFCNEELEDNLMLKLTQEFKQFETIFVRRIDNSIFNARIFTVDEELDFAGHPILGAAATIHSNIFRNEEDIAITFQLNQKTIIVNSKKIEEYYEVQMNQGKAEFLCEVSKEKRNKYVHALNLSEENLSEEFPMEVVSTGLPYLLVPLTSGIENAKIISSKFEEMLKEVGAKFAYIFDVNYIEGRTWDNQGNVEDVATGSAAGPLGAYLYKHNIFNVGHEIIINQGRFVGRPSKIKVSMSISEKEILVSGEVAILAKGTILL
>NC_017297.1|WP_012100157.1|2373124_2373814_-|CRISPR-associated-endoribonuclease-Cas6
MEFWELIVTAMLKKDIYFEDCGYIIGKNINKSMLWDKDLKEVHPKKQYKNYVFNSFYPIERDKFYKKDRLYIFNIRGLSKEFIDKIETCLCNLESNDFNVISTSKKEIKQRYIKELYTQTPLIITVDDKPWLQNDGDLDLFKQRLEDNLEKKYKSFFNEDIDVKGKFIKSIEFKNRKPMHYNYKNGKKLLANKVSIQIEDNEEAQKVAFLARAIGLGEKNPSIGAGFCK
>NC_017297.1|WP_012100156.1|2371897_2373079_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MERVKVTLGVVTDMFSEGVNSNKEAEFRITELKALLRSTFREFFYYTSLDDLKEKEELLFGSTNRKSPVIIKFGRNNKIRFKDKKKLVLHKNMFKEAIPSGTTINIIFQSRYEKYLKTYVYTLKLASIMGALGKRSRKGMGAFKIIKIDDNEIIDINKSVEDLLCGYEEQFKINEKIYLIKTRKLLKEKQYKDNCTKYKIECDANMPKNVNYVKNIYKIYLGNLTEEKSRNKIDCTLRNFSWLNHYRLSDLNKIFSNETIKKIEKETGKRIDNEISLENLFNKEILGNYNYKYKEKEVTKKNILTRFACPVYVTIYQKSRGELIENYLIIKELNYDYVYKKILDKKVSNKKVTEQKKEEIRTDIKSELKEMKPIDKYYVEEFVKKIIECCEVK
>NC_017297.1|WP_012100155.1|2370149_2371895_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MSYLLGVTVGPIQTNIQKSRKLRELYNSSKIVSDMMKKVIEYLKIRDETLKIIYPSIKDVNDTKTDITNYLICEINNIDDLKDMRERVFDELKISVLEEIYFMFWAVEPLEEYSKTYKKLTKKLRSIKNTYEFKNYEKDVRIKKKCSLCGERIREDASELCEVCNRKRNYDQTSNWKNNNKGEKYKSVYDISIDAWKEKYNEDLLSLNKNLEDLFNNTSRYYSLDTVSNIIKCLKIDPKKVRKEKEIDEDLENPKMEALELIAELKNIRFELESIYLRGEKPVSKPHYKYCFIQIDVDDLGKWISGVYNYEEENLKENQIQISKALCSFAYKLKEEFKNSKTKVIYAGGDDFLAVLPVECLLNTLKIIEEIFKSTVQNNIDNSLNYSQKISYSASVTIANCKDEMSLALRKNREALEKVKNRYYSKNGICINYIINTSKIINMFLLKDYFNEYVDNLRYFKKVEKYMSFTYIDAIENEFSKMKFEDLETDDFLNIKDMLLLEFERHLNLNKNKVPKDSEEGNENFLEYFKIHTRLFENIINDNEIDKKIDFINIINCFRIYKKLTDFQFKEEAKWDEVSKN
>NC_017297.1|WP_012100154.1|2369065_2370169_-|CRISPR-associated-protein-Cmr3
MKFLKIKPYDNTFFRLGNNFEFKISNVIQTKNVAYPSTFFGAIFTAILANNDEFRESFLNIPGNTDHLEILNIKQIYLYAEKQGMIYIKAPKDIFVNNNEVKFGNFKEIKDGESSIKYDYYLEEPDGNELERADNYFVSIKEFYDKYRYKVLDNIDLKQEDEIFAKNIKTGIALDKSTGIVKESLLYTIEQTEFKNITEDYYSNDWSFVVEYAIDNDFLKKQGYPKVKNLDKGELKLGGETKVCTYEIIENSDINEFKSKTSQGFLKPGEKLKVILTSDSYFTKSFAELFNDEMKILALVNDKPIYIGGFDVAKNEEKAMYKGYSAGTVLLLQNESGKDINLQKYLDMKLRNKLKNGFNEYICVKGE
>NC_017297.1|WP_012100153.1|2367791_2369063_-|hypothetical-protein
MEHKNVEHLVIFSTLNQITNYIAIKNLKPKNIYNITFDQGFADTLKQGIDPKKWDDNLKNVLNDENIKPKRKNIEIKQCMYIDLEKFKEELEKNIEYVDEDTPIYWHITGGQRIFAIAIHDIVKKRPNDIIFYLEGNSEKIIYIGKEKTKFEYELKDLDFSTAFKLMGYNTEDLDSTRILKGKIKKNDKNEKLKYDKNEMKFYHRLYDWIINNDGEKTKSHIAFSIGDKKFEGTFKKLLLESNSINRTIRQEFLKKLFEELEKKSPSLKKIEYNFINSDEMKMEFPAGYIFEKLTGYQIYKVVEDNTRILGMAMSLKVYNEEGGHSTDELDIALLTNTGRIINFECKSGSLKGDNAKSHKFTTYSLSGVFGAPIFLTPLTYKGEKLEKELDKKLHSACKAADRANLEKIYLKDIKEKVKKLIG
>NC_017297.1|WP_012100166.1|2385349_2386249_+|hypothetical-protein
MSNKRNLQSLRSFYICILIFNMVSNSIFHLNNNGFNIKLFKNFTIRSVILLDLNILLFLIIVIAFEKKINIDEEANTQLNTRIRPLYLVNIFFIAYILVCIFLLKDIDVILSSFIMEIIYIGIIILSKKIITLELTNRQLQWQKACGYIDEDCEESSFLWRFKLWWSPHVNVPFKNRWKGSSRLLYDLALVYGIIISKGNLFSLILLILLLPDVISWLEGLLGLQTSLTGICTGITEHHSKNSHVLYHKVYVTDYKNKREITFYVDGPLFIHENSHMTVVHGTFSKRVLYVEGLNLDIR
>NC_017297.1|WP_012100167.1|2386588_2387911_+|APC-family-permease
MLEKKYGLWTTVSMVIGIVIGSGVFFKADNILMASGGNVKTALLAWLVGAISMIFGALVFAECANRFERSNGIVDYAEGMLSEKFAYLIGWFNGIIYYPAIAAVLAWAAGNYTAILFNKDGNFVWIMAAIYMIGIYILNYISPILSGKFQIASTAIKLVPLMIIAIFGIFQGVNNGILIENFSKVSIISDSGSGFAAAVLGAAFAYEGWIIATTINGEIKDAKNTLPKALVFGSLVIVIIYILYFLGIVGMIPTETILKQGDNTVNVAARTVFGNFGASILTIFIIVSCLGTLNGLILGGSRSFYSLAIRGQGIKPDAFSKLNSKTNIPTNSTIANFILICIYLVVWYMNFKGLFPNKMFVDISELPIALIYGIYIIIYIAYMMKMKDLSFIKRFVIPSLALMGALIVVYGGLSKPSVIIDLGISVFVFLSGLLFYNKKK
>NC_017297.1|WP_012100169.1|2387978_2388713_-|protein-kinase-family-protein
MVIKFLKRDTKYLPEQKIHEYTVLKVLGEGRFGICYLVQSNNKQYILKQLKTKMLKKVGSKVIYEQEILKNINHNCIPKFVKTLQFEKIFGYVLKYKEGKTFEEIICEDEYVFKREEIYDICIQIIEILKYLHKNGIVHRDIRIPNTIYYKKKVNLVDFGLARWINNKRYTENVDFSYLGDFLLHLYYTSFQCKTFKGKPWYEELDLFSEEMNFLKRLLGIEKKYKNIEEVERDFLLLKSNYNK
>NC_017297.1|WP_012100170.1|2389215_2389989_-|2-hydroxyglutaryl-CoA-dehydratase
MYTMGLDIGSTTSKGVIMKDGKEIVASVLVPVGTGTSGPLKLIKELKEKSNLTEKDIEKTVVTGYGRIQYKDADKQISELSCHAKGVAFLIPGARTIIDIGGQDAKAMKLNDKGKLINFIMNDKCAAGTGRFLDVMAGVLETDVSKLGEISEKSTKEVSISSTCTVFAESEVISHLSANAKKEDIIAGIHTSVVRRVSTLAMRVGIEDQVVMVGGVARNKGIVKAMEKELGHDIKVPELAQLTGALGAAIYAFEETK
>NC_017297.1|WP_012100171.1|2390082_2391648_-|membrane-protein
MSENSKSKVGFLTAFQVAAVWFGAHVGGGFATGNQTMNFFVKHGWHSIWLPAVIIIIIGLTYKESLILAKNYGTYDYKSWSKKMYEPYDKVFSFIFEIGYLMIVLLGTGGSIAGSASLMETYGVNYLVGVLITGGIFYILTIYGSELIRKASTIITVLILIFLTIIVIVGIVNNSGNLSHLVSTKYSPSSFGTVLYSGLRYAGYQAFVVAIVLSASDTLKSDKAINKSILLGVILNGAMITLSCIMLLAWMPGAQKETIPILYICKRLNDGFLLFSYSVVLFLAFVSTGIGCVFGAVARFEHVFKKPENIKKRRGLISLVCMILSMAISLFGLTKIVVIGYGYVGIIGIFVVVIPCIVVGRIKNNKFKKEQQSILIENKDDTSSKEDNDNVLIGDQDDMLEENKDSILQDQDDISKEDEENMPVEEQDDASKENKESVSVEDQVDVLKGEQDSVPEGEDDTLKEDGENAPVEGQDDASKGNKKSVLVEGQDDMPKEDKESASIEEQKSTSTQEDGNASKEE
>NC_017297.1|WP_004451547.1|2391947_2392997_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MDIKKDLSSYKNVWVIAEQRQGKITPVVIELLGEGRKIANDIGVELCAVLLGYNVDNLADELIKFGADKVYYANDPLLEKYTTDGYAKVIVDAVNDIKPEIVLIGATHIGRDLAPRIASNLDTGLTADCTKLEVDPEDKKLKQTRPAFGGNIMATIICPDNRPQMSTVRPGVMDKAVKDESRKGQILKLSADLIKDDIRTEVIEIVKSKKELVSLTDANFIVSGGLGLGNPDGFKLLKQLADRLGGVVGSSRAAVDAGWIENSHQVGQTGTTVKPTVYIACGISGAIQHLAGMQESDIIIAINKNESAPIFEVADYGIVGDLYDVVPKLLELLDDDDRINRLFEESKIV
>NC_017297.1|WP_012100172.1|2393015_2393801_-|electron-transfer-flavoprotein-subunit-beta/FixA-family-protein
MRIIVCVKQVPDTTEVKIDPKTGTLIREGVPSILNPDDANALEEALKMKDKDENVTVSVVSMGPPQADVMLRECLAMGADEAYLVSDRAFAGSDTWATSKVIASAIRKIGNYDIIFAGRQAIDGDTAQVGPQISEKLGIPQVTYVQDFRMEDDKITVQRQLEDGYEIIRVKKPALLTAVSSLNEPRYMAVDKIFDAYKKEIKVLTIDDLDIEKEGVGLKASPTKVFRSFTPAPKGKGVMLEGSTEEMVEKLVVSLKQKHII
>NC_017297.1|WP_012100173.1|2393839_2394973_-|acyl-CoA-dehydrogenase
MLFKKEHELLRKSVRDFVDRELKDIPEEVDTEGKLPKELLQKLAKYKFISPVIPKEYGGAGADYVSYCIIMEEISKRCASTGTFITAGASLVALPLLNFGTDKQKEKYLKPLAKGEYIGSFGLTEPGAGSDAGAGETTAVLEGDYYILNGRKTFITNAPICDFAIVTAMTEKGKGSRGISAFIVESKWDGFSTGAHENKMGIRGTETADLIFENVKVPKENLIGKEGKGFKIALNTLDVGRIGVAAQALGIAQGALDEAIKYVKERVQFGRPLAKFQNTQFTIADMETKVQAARWLVYDAAEKKDNGINPGVESAMAKYYAAEIANEVAYKALQLHGGYGFMKDYPIERMYRDARITSIYEGTSQVQQMVIAAKALK
>NC_017297.1|WP_004451550.1|2395470_2396598_-|2-hydroxyacyl-CoA-dehydratase
MDNIKNILSKLEVIVKNPKKVVSDYKERTGNKVIGCFPVYTPEEIVYAADMLPIGIWGGDVEANLAKQYYPAFCCSIMQSCMEFGLKGVYEGLSAVIIPGMCDTLNCMGQNWKFAIKDIPYIALVHPQNRKLEAGVEYLVEEYKHVKAKIEEIRGKEITEEELQNSIEIYNEHRKVMRSFVDEAAKHPNTINNYQRNLVIKSGFFMRKDEHTKIVKELNELLSVLPEEKYDGKKVLVTGILLDSKEMLDVFEENKLRIVADDLAQESRQFRTDVPEGKDALDRLARQWSNIEGCSLAYDPKKIRGSMIAKEAKAKGIDGVVFAMMKFCDPEEYDYPIVKKDIEKGDIPTTMIEVDQQNKSVEQIRTRIQTFSEIL
>NC_017297.1|WP_003358160.1|2396597_2397830_-|2-hydroxyacyl-CoA-dehydratase
MADKKEVKKNAAKVINGILAKSYADAWKAKEEGRPVGWSTSVFPQELVEVFGLDVLYPENQAAGVAAKKESLSLCEAAESAGYSIDLCAYARTNFGLLEKGGSENLNMPKPDFICCCNNICNQVIKWYENIAKELDIPLIMIDTTFNNENEVTENRIKYLRAQFEEAIKQLEKISGKKFDPKKFEEVMKISAENGKLWKYSMSLPSGSFPSPMNGFDLFTYMAVIVCYRGKIETTEAFKLLISELEDNIKNKATSFRGEEKYRIMMEGIPCWPYIGYKMRTLAGYGVNMTGSVYPHAWALQYEVNDLDGMAKAYSTMFNNVNLERMCKYRVDSLIDGNCDGAFYHMNRSCKLMSFIQYEMERQVFEKTGIPYAGFDGDQADPRNFSKAQFETRLQGLVEVMEERKKGGNK

Crispr_ID: NC_017297_14

• CRISPR_ID: NC_017297_14
• CRISPR_location: 2476163-2476408
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: casR

Consensus repeat of NC_017297_14

Consensus_repeat	Method
TCTTCTTTCGCANTCTCT	CRT

spacers of NC_017297_14

>14.1|2476181|30|NC_017297|CRT
TCTGCATCTTCTTTCACATTCTCTTCTGCA
>14.2|2476229|30|NC_017297|CRT
TCTACATCTTCTTTCACATTCTCTTCTGCA
>14.3|2476277|18|NC_017297|CRT
ATCGCGATCTCTTTCGCA
>14.4|2476313|18|NC_017297|CRT
TCTACATCTTCTTCTGCA
>14.5|2476349|42|NC_017297|CRT
TTCGCACTCTCTTTCACACTCTCTTCTGCATCTTCTTCTGCA

CRISPR arrays and Neighbor proteins around NC_017297_14

CRISPR arrays

The CRISPR arrays of NC_017297_14

>merge|NC_017297|14|2476163-2476408|CRT
TCTTCTTTCACATTCTCTTCTGCATCTTCTTTCACATTCTCTTCTGCATCTTCTTTCGCATTCTCTTCTACATCTTCTTTCACATTCTCTTCTGCATCTTCTTTCGCACTCTCTATCGCGATCTCTTTCGCACTCTCTTTCGCACTCTCTTCTACATCTTCTTCTGCATCTTCTTTCGCACTCTCTTTCGCACTCTCTTTCACACTCTCTTCTGCATCTTCTTCTGCATCTTCTTTCGCACTCTCT

>NC_017297|14|4|2476163-2476408|CRT
TCTTCTTTCACATTCTCT	TCTGCATCTTCTTTCACATTCTCTTCTGCA
TCTTCTTTCGCATTCTCT	TCTACATCTTCTTTCACATTCTCTTCTGCA
TCTTCTTTCGCACTCTCT	ATCGCGATCTCTTTCGCA
CTCTCTTTCGCACTCTCT	TCTACATCTTCTTCTGCA
TCTTCTTTCGCACTCTCT	TTCGCACTCTCTTTCACACTCTCTTCTGCATCTTCTTCTGCA
TCTTCTTTCGCACTCTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_012100244.1|2480050_2480458_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100238.1|2473391_2473730_+|hypothetical-protein	unknown	unknown	gnl|CDD|378946
NC_017297.1|WP_079996738.1|2478729_2479488_+|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein	unknown	unknown	gnl|CDD|235613
NC_017297.1|WP_012100233.1|2468644_2470438_+|M24-family-metallopeptidase	unknown	unknown	gnl|CDD|238518
NC_017297.1|WP_003400697.1|2476819_2477023_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100239.1|2473894_2474896_-|linear-amide-C-N-hydrolase	unknown	unknown	gnl|CDD|227264
NC_017297.1|WP_101502759.1|2474972_2475080_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_003392410.1|2479582_2479750_-|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl|CDD|378175
NC_017297.1|WP_004451635.1|2466983_2467313_-|DUF3147-family-protein	unknown	unknown	gnl|CDD|181745
NC_017297.1|WP_012100236.1|2472357_2472606_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100232.1|2467300_2467729_-|MarR-family-transcriptional-regulator	casR	cls001593_casR_CAS-I	gnl|CDD|197670
NC_017297.1|WP_012100237.1|2472926_2473196_-|DUF1599-domain-containing-protein	unknown	unknown	gnl|CDD|377892
NC_017297.1|WP_004451638.1|2467870_2468467_-|DUF3862-domain-containing-protein	unknown	unknown	gnl|CDD|289729
NC_017297.1|WP_014519337.1|2478505_2478733_+|hypothetical-protein	unknown	unknown	gnl|CDD|235613
NC_017297.1|WP_012100247.1|2481985_2482582_-|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
NC_017297.1|WP_012100242.1|2477834_2478167_+|hypothetical-protein	unknown	unknown	gnl|CDD|378946
NC_017297.1|WP_012100246.1|2481304_2481754_-|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl|CDD|234692
NC_017297.1|WP_134865116.1|2476663_2476762_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_012100240.1|2475093_2475675_-|flavodoxin-family-protein	unknown	unknown	gnl|CDD|223728
NC_017297.1|WP_012100245.1|2480538_2481132_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017297.1|WP_012100232.1|2467300_2467729_-|MarR-family-transcriptional-regulator	casR	cls001593_casR_CAS-I	8.9e-11	36.1	3.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_012100238.1|2473391_2473730_+|hypothetical-protein	gnl|CDD|378946	pfam12788, YmaF, YmaF family. This family of proteins contain 6 HXH motifs and is named after the B. subtilis YmaF protein. It seems likely that these are involved in metal binding. The function of this protein is unknown.	1.44653e-44
NC_017297.1|WP_079996738.1|2478729_2479488_+|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein	gnl|CDD|235613	PRK05802, PRK05802, sulfide/dihydroorotate dehydrogenase-like FAD/NAD-binding protein.	6.11268e-140
NC_017297.1|WP_012100233.1|2468644_2470438_+|M24-family-metallopeptidase	gnl|CDD|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	3.8233e-89
NC_017297.1|WP_012100239.1|2473894_2474896_-|linear-amide-C-N-hydrolase	gnl|CDD|227264	COG4927, COG4927, Predicted choloylglycine hydrolase [General function prediction only].	1.3893e-81
NC_017297.1|WP_012100247.1|2481985_2482582_-|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	2.71006e-85
NC_017297.1|WP_003392410.1|2479582_2479750_-|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl|CDD|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	0.00142629
NC_017297.1|WP_012100232.1|2467300_2467729_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.79196e-16
NC_017297.1|WP_012100237.1|2472926_2473196_-|DUF1599-domain-containing-protein	gnl|CDD|377892	pfam07659, DUF1599, Domain of Unknown Function (DUF1599).	1.23666e-15
NC_017297.1|WP_004451638.1|2467870_2468467_-|DUF3862-domain-containing-protein	gnl|CDD|289729	pfam12978, DUF3862, Domain of Unknown Function with PDB structure (DUF3862). Structure 3D4E shared structural similarity to beta-lactamase inhibitory proteins (BLIP) which already include 1XXM, 1S0W, 1JTG, 2G2U, 2G2W, 2B5R, and 3due. All of structures are involved in beta-lactamase inhibitor complex. (REF http://www.topsan.org/Proteins/JCSG/3d4e).	3.95982e-08
NC_017297.1|WP_014519337.1|2478505_2478733_+|hypothetical-protein	gnl|CDD|235613	PRK05802, PRK05802, sulfide/dihydroorotate dehydrogenase-like FAD/NAD-binding protein.	1.68378e-43
NC_017297.1|WP_012100242.1|2477834_2478167_+|hypothetical-protein	gnl|CDD|378946	pfam12788, YmaF, YmaF family. This family of proteins contain 6 HXH motifs and is named after the B. subtilis YmaF protein. It seems likely that these are involved in metal binding. The function of this protein is unknown.	4.56319e-44
NC_017297.1|WP_004451635.1|2466983_2467313_-|DUF3147-family-protein	gnl|CDD|181745	PRK09272, PRK09272, hypothetical protein; Provisional.	1.6575e-33
NC_017297.1|WP_012100240.1|2475093_2475675_-|flavodoxin-family-protein	gnl|CDD|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.5911e-26
NC_017297.1|WP_012100246.1|2481304_2481754_-|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl|CDD|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	1.65596e-88

Protein sequences

>NC_017297.1|WP_012100240.1|2475093_2475675_-|flavodoxin-family-protein
MKYCILMGSPRKNGNTFKLLKPFIEELELQQVQYDLIWLYDKHIEPCTACRNCQKDWTIFGCRYSDDVQEIFDKVYDSDVIILATPIYSWYCTPPMKSLLDRLVYGMNKYYGDEKGPSLWSGKKLAIITTCGYRPENGADLFEEGIKRYCKHSKLKYIGMLAERDFGYKSVFITDDKIEHSRSFARKLISDKV
>NC_017297.1|WP_101502759.1|2474972_2475080_-|hypothetical-protein
MIYNFLVTCNNYIITLDRIIQYEYAVFLFTNLNSC
>NC_017297.1|WP_012100239.1|2473894_2474896_-|linear-amide-C-N-hydrolase
MYHSRWKGSHYEAGLHYGNILHKNGVNPMSSIPISDERKEFSVKCLPIYEKFYPEIVEEIKGMANGLKIGYMDIASFIFTMYCFVFDNKCSCLAISNKGKTLFARNSDFVVSIEKLCDSAYYKLNNVYSFVGNTTAWTEMEDGINEHKLAVGLTFIYPIKIKPGFNAGMLVRYILEKCKTTDEAILALKKLPIASPQTITLADKSGNIAVVECNCDKVVVLNPQQGKNYVFTTNHFISEEMQEYQFNGVDDVHSHERYETLVNAFGNSKDYSLDFIKNLLSGKMGFMCQYDRKQGLDTVWSSIYDLTEGTIFRVEGNPSRKVFKKDKRLIFAK
>NC_017297.1|WP_012100238.1|2473391_2473730_+|hypothetical-protein
MCNCEKRERQTHVHEFLGSTRLAEIQTEPHNHRFAGVSGQAIRSGNSHVHRITTNTDFFDHFHMINVLSGPAIPVGNGRHVHFVSGVTSVNDGHRHEFIFATLIEAPIFEED
>NC_017297.1|WP_012100237.1|2472926_2473196_-|DUF1599-domain-containing-protein
MMDKANKHKIICEELNKIYKVKNHDYGDSFGETYKKLGIISAVTRITDKVNRLQSLCIKDALVDESIKDTLIDLANYSIMTLIELEEEE
>NC_017297.1|WP_012100236.1|2472357_2472606_-|hypothetical-protein
MAEQIKTNSTPIRIQRNANDVAMELLDIYLKDQYETDKPMQADYLRNLYLKFYATAEMAERIHFKYLKEYLPEGLKEMAEKF
>NC_017297.1|WP_012100233.1|2468644_2470438_+|M24-family-metallopeptidase
MKVSERLIKLRNLMTEKNIDMYIVPTADFHQSEYVGEHFKARKYITGFSGSAGTAVITKGNAGLWTDGRYFLQAGNQLKGTTVELFKMGEPGVPTIEEYIMNTLSDKGTLGFDGRVVSMVDGQTYEKILSSKNANINYDCDLINDIWEDRPSLSEEPAFELDIKYTGESTASKLKRVRKAMTDAGTNVHVITSLDDIAWILNIRGNDIEFFPLVLSYLIITMDEAHLFINEDKLSDEIKSNLKKNGVSFIHPYNEIYKAVKKFNTSDIVLVDPARMNYALYNNIPKDVKKVENRNPSVLFKAMKNPIEIENIKKAQIKDGVAHTKFMYWLKHNIGKETITEISASNKLDEFRAEQGGFIRPSFEPISSFAEHAAIVHYAPTPETDVELKEGSLFLTDTGAGFYEGSTDITRTYALGEVPQIMKDHFTLTVNSNMHLAHARFLYGCNGMNLDILARAPFWNRGLNFNHGTGHGVGYLMNIHEAPTGFRWQYRANETHPFEEGMVITDEPGIYIAGSYGVRIENELLVCKGEQNEYGQFMYFEPISYVPIDLDAINPDLMTAEEKAWLDEYHESVYNKISPYLTEEEKNWLKEYTRKIS
>NC_017297.1|WP_004451638.1|2467870_2468467_-|DUF3862-domain-containing-protein
MLEKKEEPFYKKIWFWIIAIVIVCGVASYGDSKKINITDTKNSAKTETKKDDTRKVTYEKFCKIKIGSTYEEVKSILGEYKESKESEINGMKVVIYSWYNDDNSNMEVIVKNNKVIGKAQAGLSMGKADVNLIKYAKITTGMDYSKVEEILGDGKLMSISKTNGSTKSIYLWANPNGTNMNVTFQNGKVTAKNRLGLN
>NC_017297.1|WP_012100232.1|2467300_2467729_-|MarR-family-transcriptional-regulator
MMKLENRIRIINEEWTDIYYLLHYIDKENLTHQAIRLLQYIDKNKETTIGDLAKHISTSSNTASEHIKRLIKKGLVTKQRSEVDERKVIVKITEEGKHTLHRHINLDEAKLKKVLGSLTDSELEVIQKGFLILSEGAKKCLP
>NC_017297.1|WP_004451635.1|2466983_2467313_-|DUF3147-family-protein
MFTVVKVFISAIIIGVVTEIARKSPTYGGIIAALPIVSLLSLTWIYIQGEQTQNLSKFVFGVLKGFPATIILLLVIGLSLRANRSLVLSIFLGACGWGVILAVQNFIFN
>NC_017297.1|WP_134865116.1|2476663_2476762_-|hypothetical-protein
MKLTQKQKVFDDYYIETGNVKKQLLKLDIVKK
>NC_017297.1|WP_003400697.1|2476819_2477023_-|hypothetical-protein
MGVENPTCHVKILNNETKESVYHWRKEINIVEIEAIKISKKVYCNNQYYDIKTLVFNYDNLTLEIII
>NC_017297.1|WP_012100242.1|2477834_2478167_+|hypothetical-protein
MSYCEEMQTHVHEFLGSTRLAEIQTEPHNHRFAGVSGQAIRRGNSHVHRITTNTDFFDHFHMINVITGPAIPVGDGRHVHFVSGVTSVNDGHRHEFIFATLIDSPIFQEA
>NC_017297.1|WP_014519337.1|2478505_2478733_+|hypothetical-protein
MEYEIKDCIDAGSEYCPCHLAETGDCILCSQLSGKKFCDCINWKGVCIYQEFIWNRKKAKEERETYLGKIIKKIT
>NC_017297.1|WP_079996738.1|2478729_2479488_+|sulfide/dihydroorotate-dehydrogenase-like-FAD/NAD-binding-protein
MEDKTIVLTISLSHKLCQQLVYPGSFVFLRNKNDSGFYDAPISIMDVDTEENFIKVAIEIRGVKTKTIASLNKNDDIWVRGPFWNGVLGLKNVYMTKDGTSLLISRGIGQAPLVPVMKKLYSNGNKIIAIIDNSGYENILIKNYLELYNAEVIELNTLKAGELTEELKNKLKEILDKEDINIIHCSTQDIIIYKLVEFLDGKVPISSSNNAKMCCGEGVCGTCTVRYKGHIVKRLCKVQTEPKYVFRERRLI
>NC_017297.1|WP_003392410.1|2479582_2479750_-|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MSKEQLLLEKIEEARTLMNQLISEKSQLIDEELVLLSQKLDDLLNEYNKFLRQNH
>NC_017297.1|WP_012100244.1|2480050_2480458_-|hypothetical-protein
MQIITGAVVNILGVVIIYLSTVVVQYFKQKRQASINQMGNEQYNMHYNIAKSIFYAIEQEYRLVSKSGEQKAEKFNKMLMEKIPSLKQEDLDHFREAIVGEINTQIKQSKLLEPADSITNEKKQLLDSKENKIEN
>NC_017297.1|WP_012100245.1|2480538_2481132_-|hypothetical-protein
MKSIFKKLMPIIFIAILSISLTGCSSKPDETVKGFFGALKQQDIKKASTFINANSFYKELKVDEFDSKEQEKIVKAVLSKFDYSLGDVEKNGNTATAKVSVTSIDLGKITIKTIDKVLPNLIDEAFSKGKIDEKKQQAVIIQHMLNSINDPNAPKIKTNINVKLVKGDKGWLIEPDEELANALSGNLYSVAKKFQSK
>NC_017297.1|WP_012100246.1|2481304_2481754_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MNKNYSKKSKEELKKILTPEEYYVTQENGTEAPYKNEYWDLNEEGIYVDITNGEPLFTSKDKFNSSCGWAAFSKPIDRKIIKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEKLGGLRYCINSASLKFIPKNELEEEGYGEYLKLFK
>NC_017297.1|WP_012100247.1|2481985_2482582_-|superoxide-dismutase
MAHTLPNLNYDYNALEPHYDEQTLKIHHDIHHKVYVDGLNKAEQKLQEARESGDFALIKHWEKEIAFHGSGHILHTLFWENMVPNGNLNPEGSAIERIKQDFGDYEKFKKQFTEAAIAVEGSGWTILAWNPMFQKLVILQAEKHQNLTQWGVVPLLILDLWEHAYYLKYQNRRAEFINAWWNIVNWDIVNTRYDNAIK

Crispr_ID: NC_017297_15

• CRISPR_ID: NC_017297_15
• CRISPR_location: 3875654-3875767
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017297_15

Consensus_repeat	Method
AGGACTTGAACCTACGACACTTCGGGT	CRISPRCasFinder

spacers of NC_017297_15

>15.1|3875681|60|NC_017297|CRISPRCasFinder
ATGAACCGAATGCTCTAGCCAGCTGAGCTATTCCGCCAAAAAATAATTGGTTGCGGAGGC

CRISPR arrays and Neighbor proteins around NC_017297_15

CRISPR arrays

The CRISPR arrays of NC_017297_15

>merge|NC_017297|15|3875654-3875767|CRISPRCasFinder
AGGACTTGAACCTACGACACTTCGGGTATGAACCGAATGCTCTAGCCAGCTGAGCTATTCCGCCAAAAAATAATTGGTTGCGGAGGCAGGACTTGAACCTACGACCTTCGGGTT

>NC_017297|15|14|3875654-3875767|CRISPRCasFinder
AGGACTTGAACCTACGACACTTCGGGT	ATGAACCGAATGCTCTAGCCAGCTGAGCTATTCCGCCAAAAAATAATTGGTTGCGGAGGC
AGGACTTGAACCTACGACCTTCGGGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017297.1|WP_003399650.1|3864287_3865115_-|hypothetical-protein	unknown	unknown	unknown
NC_017297.1|WP_003495805.1|3881667_3882219_-|stage-V-sporulation-protein-T	unknown	unknown	gnl|CDD|131898
NC_017297.1|WP_012101157.1|3878539_3879985_-|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl|CDD|226465
NC_017297.1|WP_012101156.1|3877410_3877701_-|sporulation-protein-YabP	unknown	unknown	gnl|CDD|274341
NC_017297.1|WP_012048379.1|3877820_3878060_-|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl|CDD|224109
NC_017297.1|WP_012101155.1|3872923_3875311_-|stage-II-sporulation-protein-E	unknown	unknown	gnl|CDD|274328
NC_017297.1|WP_003359441.1|3866145_3866922_-|type-III-pantothenate-kinase	unknown	unknown	gnl|CDD|237347
NC_017297.1|WP_003361709.1|3863674_3864157_-|transcription-elongation-factor-GreA	unknown	unknown	gnl|CDD|234693
NC_017297.1|WP_003359333.1|3878133_3878412_-|HU-family-DNA-binding-protein	unknown	unknown	gnl|CDD|259853
NC_017297.1|WP_003359471.1|3876166_3876571_-|RNA-binding-protein-S1	unknown	unknown	gnl|CDD|235614
NC_017297.1|WP_003359350.1|3876632_3876902_-|septum-formation-initiator-family-protein	unknown	unknown	gnl|CDD|368217
NC_017297.1|WP_012101154.1|3871368_3872775_-|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl|CDD|274129
NC_017297.1|WP_003399652.1|3867076_3868750_-|formate--tetrahydrofolate-ligase	unknown	unknown	gnl|CDD|376511
NC_017297.1|WP_003359440.1|3876996_3877395_-|spore-cortex-biosynthesis-protein-YabQ	unknown	unknown	gnl|CDD|131939
NC_017297.1|WP_012101158.1|3879999_3881535_-|polysaccharide-biosynthesis-protein	unknown	unknown	gnl|CDD|240529
NC_017297.1|WP_012101153.1|3868952_3870758_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl|CDD|273520
NC_017297.1|WP_003359412.1|3870839_3871385_-|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|223707
NC_017297.1|WP_003359337.1|3862141_3863656_-|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778
NC_017297.1|WP_012101159.1|3882417_3883428_-|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|234605
NC_017297.1|WP_003399651.1|3865164_3866136_-|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl|CDD|129820

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017297.1|WP_003495805.1|3881667_3882219_-|stage-V-sporulation-protein-T	gnl|CDD|131898	TIGR02851, stage_V_sporulation_protein_T, stage V sporulation protein T. Members of this protein family are the stage V sporulation protein T (SpoVT), a protein of the sporulation/germination program in Bacillus subtilis and related species. The amino-terminal 50 amino acids are nearly perfectly conserved across all endospore-forming bacteria. SpoVT is a DNA-binding transcriptional regulator related to AbrB (See pfam04014). [Regulatory functions, DNA interactions, Cellular processes, Sporulation and germination].	2.98462e-94
NC_017297.1|WP_012101157.1|3878539_3879985_-|nucleoside-triphosphate-pyrophosphohydrolase	gnl|CDD|226465	COG3956, COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only].	0
NC_017297.1|WP_012101156.1|3877410_3877701_-|sporulation-protein-YabP	gnl|CDD|274341	TIGR02892, conserved_hypothetical_protein, sporulation protein YabP. Members of this protein family are the YabP protein of the bacterial sporulation program, as found in Bacillus subtilis, Clostridium tetani, and other spore-forming members of the Firmicutes. In Bacillus subtilis, a yabP single mutant appears to sporulate and germinate normally (), but is in an operon with yabQ (essential for formation of the spore cortex), it near-universal among endospore-forming bacteria, and is found nowhere else. It is likely, therefore, that YabP does have a function in sporulation or germination, one that is either unappreciated or partially redundant with that of another protein. [Cellular processes, Sporulation and germination].	6.9263e-31
NC_017297.1|WP_012048379.1|3877820_3878060_-|RNA-binding-S4-domain-containing-protein	gnl|CDD|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	1.13439e-24
NC_017297.1|WP_012101155.1|3872923_3875311_-|stage-II-sporulation-protein-E	gnl|CDD|274328	TIGR02865, Stage_II_sporulation_protein_E, stage II sporulation protein E. Stage II sporulation protein E (SpoIIE) is a multiple membrane spanning protein with two separable functions. It plays a role in the switch to polar cell division during sporulation. By means of it protein phosphatase activity, located in the C-terminal region, it activates sigma-F. All proteins that score above the trusted cutoff to this model are found in endospore-forming Gram-positive bacteria. Surprisingly, a sequence from the Cyanobacterium-like (and presumably non-spore-forming) photosynthesizer Heliobacillus mobilis is homologous, and scores between the trusted and noise cutoffs. [Cellular processes, Sporulation and germination].	0
NC_017297.1|WP_003359441.1|3866145_3866922_-|type-III-pantothenate-kinase	gnl|CDD|237347	PRK13318, PRK13318, type III pantothenate kinase.	7.15192e-153
NC_017297.1|WP_003361709.1|3863674_3864157_-|transcription-elongation-factor-GreA	gnl|CDD|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	1.82122e-76
NC_017297.1|WP_003359333.1|3878133_3878412_-|HU-family-DNA-binding-protein	gnl|CDD|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	4.45296e-40
NC_017297.1|WP_003359471.1|3876166_3876571_-|RNA-binding-protein-S1	gnl|CDD|235614	PRK05807, PRK05807, RNA-binding protein S1.	4.75791e-79
NC_017297.1|WP_003359412.1|3870839_3871385_-|hypoxanthine-phosphoribosyltransferase	gnl|CDD|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	3.43574e-93
NC_017297.1|WP_012101154.1|3871368_3872775_-|tRNA-lysidine(34)-synthetase-TilS	gnl|CDD|274129	TIGR02432, tRNAIle-lysidine_synthase, tRNA(Ile)-lysidine synthetase, N-terminal domain. The only examples in which the wobble position of a tRNA must discriminate between G and A of mRNA are AUA (Ile) vs. AUG (Met) and UGA (stop) vs. UGG (Trp). In all bacteria, the wobble position of the tRNA(Ile) recognizing AUA is lysidine, a lysine derivative of cytidine. This family describes a protein domain found, apparently, in all bacteria in a single copy. Eukaryotic sequences appear to be organellar. The domain archictecture of this protein family is variable; some, including characterized proteins of E. coli and B. subtilis known to be tRNA(Ile)-lysidine synthetase, include a conserved 50-residue domain that many other members lack. This protein belongs to the ATP-binding PP-loop family ( pfam01171). It appears in the literature and protein databases as TilS, YacA, and putative cell cycle protein MesJ (a misnomer). [Protein synthesis, tRNA and rRNA base modification].	3.33594e-72
NC_017297.1|WP_003399652.1|3867076_3868750_-|formate--tetrahydrofolate-ligase	gnl|CDD|376511	pfam01268, FTHFS, Formate--tetrahydrofolate ligase.	0
NC_017297.1|WP_003359440.1|3876996_3877395_-|spore-cortex-biosynthesis-protein-YabQ	gnl|CDD|131939	TIGR02893, Spore_protein_YabQ, spore cortex biosynthesis protein YabQ. YabQ, a protein predicted to span the membrane several times, is found in exactly those genomes whose species perform sporulation in the style of Bacillus subtilis, Clostridium tetani, and others of the Firmicutes. Mutation of this sigma(E)-dependent gene blocks development of the spore cortex. The length of the C-terminal region, including some hydrophobic regions, is rather variable between members. [Cellular processes, Sporulation and germination].	1.7502e-26
NC_017297.1|WP_012101158.1|3879999_3881535_-|polysaccharide-biosynthesis-protein	gnl|CDD|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.21074e-137
NC_017297.1|WP_012101153.1|3868952_3870758_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl|CDD|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_017297.1|WP_003359350.1|3876632_3876902_-|septum-formation-initiator-family-protein	gnl|CDD|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	3.85886e-08
NC_017297.1|WP_003359337.1|3862141_3863656_-|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NC_017297.1|WP_012101159.1|3882417_3883428_-|peptidylprolyl-isomerase	gnl|CDD|234605	PRK00059, prsA, peptidylprolyl isomerase; Provisional.	3.42122e-144
NC_017297.1|WP_003399651.1|3865164_3866136_-|tRNA-dihydrouridine-synthase-DusB	gnl|CDD|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	5.48793e-128

Protein sequences

>NC_017297.1|WP_012101155.1|3872923_3875311_-|stage-II-sporulation-protein-E
MQYGAELLPYQRLKKIDKQKYKKSINFSSIVNMIIFFISSFLVSRVIFINNMAPFGIAFLLSISRQKEYNKYLFISAIGSIIGYISLINNIGYTSLNMLEVVTITLLSYVFKNVEDKKNTIIICMIIYLEIFTYKIFVTKISTTMAMLGATFEIGCIFPIYYIINYSILCFKNMNTSHLYSNEEIVSMAITLSLVVSGTWGANIAGINLMNLISITMILIIGYVKGSTSASAIGVAMGAISGLSSNNMMIYISIYGLCGLISGVFKETGKLMTGISYLISFLILKFYSNINYDFKIIEVLISLTLFYIIPNKIYMKMEYELDYQKKQKNLQENYMDKIKGIITDKLGNFSDVLYNMGNILEKLVDNEKLAMKNKSGALIENLADRVCSSCNMNHICWKREGYYTYNALGELIQNYQENKKELPYEIERKCVKRTQLINNTEDIANNYIINEMWKKRLSECREVLANQINTMAYSVEEITKEFGQSIRFSNLTEKDIRRMLNKNNIKYKDIFCYNNENGRLIINLKIDACTGKQKCIKEILPLINKVTGKLMCVANESCNLDLKNNDCNIIFEETPKYHVASYVNKMAKDGEQCNGDSYSFGKLQSGSYMTIISDGMGSGPQAVQESSAVVELIERFAQSGFSKITAINTINSIMSIKFSQDEKFSTVDLSNIDLYEGKIDFMKVGAVASFIKRGTEVYTIKSKTLPIGVLDKVDIDIETRDLKNGDIIVMVSDGVLDYESSSAGKVEWVVEFLKNTTLNNPKEISEELIENAKKLSKGKVKDDMTAIVQKVYSLY
>NC_017297.1|WP_012101154.1|3871368_3872775_-|tRNA-lysidine(34)-synthetase-TilS
MKDVVINTIKKYNMIEANDKIIVGVSGGPDSMCLLHMLCLLKNQLRIKDIYVAHINHGVRGAESDADEKYVENFCYMNNLGFFSKTINMDKIAKEKGISSESAGREARYDFFNYLRKELGAQKIATAHNANDQAETVLMRIMRGTGLQGLIGINPIRDDLYIRPLINVLREDIENYCDKYELNPRIDKTNLQSIYTRNRIRLELIPYIKDNFNEDIVNTLCRFSNIVSKDNNYLEEVSKDKFERYCTKKLQRVIIDKRAFLEHESISTRILREAILYINQNLYNLEMRNIYDVLELSLNATGKFVNLPSNIKAENIYGDIHLYKEDNCIKKVNNIQCELKIGFNQVEDLNINLKIYSIKDHNYNINDNKYIQYFDYDKVSNEKIYLRNRKNGDKFTPLGMKGSKKLKDFFIDLKIPREQRDKLKLVCFGEEIAWIIGCRTGNNFKIDKNTKNVLEITVERGEANGFDK
>NC_017297.1|WP_003359412.1|3870839_3871385_-|hypoxanthine-phosphoribosyltransferase
MDLISRDIEKILISEEQIQSKINELGDQISKDYDGKNLMLVGILKGSVPFMADLLKRITIPCTMDFMAVSSYGNSTTSSGVVRILKDLDFEIEGKDILIVEDIIDSGITLKYLLENLRARKPASINIACLLNKEERRKAEIDVHYLGFNVPDYFLVGYGLDFAEKYRNLPYIGILKEEVYK
>NC_017297.1|WP_012101153.1|3868952_3870758_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MKKFSSATAWIVVLILVIFSSLMLVRTGTNSTAINFSEFQKSWIQNEIKSFQVKDDKMTVVGTLKDGKQYETIVPSERLFQFINEHPKNGEVKEVYVKPASVPIWVQYLPMILIVLMLLGFWFMFMQQAQGGGGNRNVMNFGKSKAKMATPDKKKVTFDDVAGADEEKEELAEIVDFLKSPKRYIDMGARIPKGVLLVGPPGTGKTLLAKAIAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKNSPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGANEGIIMIAATNRPDILDPALLRPGRFDRQIVVGAPDVKGREAILKVHSKNKHLAEEIKLEVLAKRTPGFTGADLENLMNESALLAVRKKKELIDMEDLEEAVTRVIAGPEKKSRVIDEEDRKLTAYHEAGHAVVMKLLPHADPVHQISIVPRGMAGGYTMHLPEKDSSYMSKSKLEDEIVGLLGGRVAEKLIIGDISTGAKNDIDRATTIARKMVMDYGMSNTLGPIAFGSGHDEVFLGRDLGKGRNFSEDVAYKIDQEIKKLIDTGYNEAERLLNENISKLHAVAQELLKKEKLEANEFEEIFKNS
>NC_017297.1|WP_003399652.1|3867076_3868750_-|formate--tetrahydrofolate-ligase
MFKSDIEIAQESKMKNIKNIAEKIGLTEEDIDLYGKYKCKISLDVLESNKDKKDGKLILVTAINPTPAGEGKSTVTVGLGQALWKKNKKAVIALREPSLGPVFGIKGGAAGGGYSQVVPMEDINLHFTGDMHAITSANNLLAAAIDNHIHQGNILKIDQRRILFKRVMDMNDRALRNVIVALGGKINGFPREDGFMITVASEIMAILCLAEDLMDLKNKMGEILVAYSTEGKPIYCKDLEVQGAMALLMKDAIKPNLVQTLENTPAIIHGGPFANIAHGCNSILGTKMALKLGDYVITEAGFGADLGAEKFFDIKCRKANLKPNCVVIVATVRALKYNGGIPKENLKEQNMEALSKGIKNLGKHIENVNKFGVPAVVAINKFISDTEEEIEFIKKYCKELGAEVSIAEVWEKGGNGGLELADKVLDTIENKESKFNPIYEETLNIKQKIETIAQEIYGAEGVDYSKEAEKQISEIEKLDLDKKPVCMAKTQYSLSDDAKLLGRPCGFRINVKEVRISNGAGFIVVLTGNVMTMPGLPKKPAANNMDVLSDGNIVGLF
>NC_017297.1|WP_003359441.1|3866145_3866922_-|type-III-pantothenate-kinase
MILVLDVGNTNIVLGIYKNKELIANWRLATDNKRTADEYGIQVIELFSHNNLSFSDIEGVIISSVVPNIMYSLEHMISKYFNIKPIIVGPGVKTGINIKYDNPKEVGADRIVNAVAAHEIYKKPLIIIDFGTATTFCAVTKEANYLGGTICPGIKISSDALFDKAAKLPRVELVKTPGVICKNTVASIQSGIIYGYAGQVDYIVSKMKKEMMDLGEEEPFVVATGGFAKLISEESKSIDEINAILTLEGLRVIYEKNK
>NC_017297.1|WP_003399651.1|3865164_3866136_-|tRNA-dihydrouridine-synthase-DusB
MNIGNLIFHNNVFLAPMAGFTDIAFREICKELGCGLVYTEMVSAKALYYESNNTKELCVISNKEKPVALQLFGHEPEIMANAVEFFNNNDDVCILDVNMGCPAPKIVKNGDGSALMKDPKLASEIIKAMKKVAKKPITVKFRKGFDKNNINAVEFAKIMEQSGVDAITIHGRTREQMYEGKADWAIISKVKSSVSIPVIGNGDVFSSEDALEMINKTDCDGIMIGRGAQGNPWIFKQINEKIKGEHVYYPTPQERIDICINHYKKSLEYFEEHKAVREMRKHVAVYVKGLKNCTDIKDKVNMEKDPDKVLEELIKYRETLREF
>NC_017297.1|WP_003399650.1|3864287_3865115_-|hypothetical-protein
MKPIIDIRSNIIKDYNKNNFIFKIKDEFLTHFRGNCFIEELNLVISKVRISPNFNEKAYHKNIKRSIKYSRHKDFVLAPKTFRFLDYYLLNSFQKELFALSVCESIKTVLRLKGKTIRNSCIVIFDAKEEYVFNIINCVSKEAKYIILVSEDLNKLANLNDYIIANYGITPIITKDIKTSFSKADFIITTKDVEIIKSIPVWYINNSKIYENKGNCNINNIIYKVPWKTNLNFNPELLGAILCQMDKKNVEEAIRYNGIVLDKIMFNKDIVKIIR
>NC_017297.1|WP_003361709.1|3863674_3864157_-|transcription-elongation-factor-GreA
MSEAKKYVMTYEGVKKLEEELEYLKTVKRKEITEKIKVALSFGDLSENSEYDEAKNEQAFVEGRIIQLENMLKNASIVDENEVPKDIVSVGSIVKVKDYEFDEEVEYIIVGSAEADPMNNKISNESPVGHGLIGKKVGDIIEVTVPDGVSKYEILEVNRA
>NC_017297.1|WP_003359337.1|3862141_3863656_-|lysine--tRNA-ligase
MSKEDNVINSFEEQANELMKERFQKLKELQSNGKDPFDVYKVERTHTSKEVKDNYEDLEGKTVTVAGRLMSKRVHGKAGFSDIHDRYGKIQLYIKINDVGEEKLKEYKTFDIGDIISVTGTVFKTKTGETSIHITDFQLVCKSLRPLPEKWHGLKDPDLRYRQRYVDLIINQDVRDTFIKRTAIIKSMREFLDNRGFLEVETPILSPIAGGAAAKPFITHHNALDIDMYLRIATELYLKRLIVGGFEKVYEIGKNFRNEGIDIRHNPEFTAIELYEAYADYNDMMEITENMIAYICEKVLGTTKVEYEGAEIDFTPPWRRLTMVDAVKEYAGVDFNIIKNDIEARTIAKEKHIEFKKELKDCTKGDVLIGLFEEFCEDKLMQPTFICDYPVENSPLTKKKRGNEAFTERFEGFVFGREVCNAYSELNDSIVQKERFMQQLKERELGDDEAYMMDDDFITSLEVGMPPTGGLGIGIDRLIMFLTDTHSIRDVILFPTMKPQPNNQ
>NC_017297.1|WP_003359471.1|3876166_3876571_-|RNA-binding-protein-S1
MTLNAGSILEGTVVNITNFGAFVEIEGKTGLVHISEVSDSYVKDIREYLKEQDKVKVKVISIDDKGKISLSIKQAMQQKKSCKPAEIDWSREKPKKNEANFEDRLSKFLKDSEERFQDLKKHQDSRGRGSKKSY
>NC_017297.1|WP_003359350.1|3876632_3876902_-|septum-formation-initiator-family-protein
MKKINVKKLIFFLAIVYSTVIFINQQITMHKIRDQISEKKIELKEVKEKNQKLQDEVKLSKSKDYIEKLARERLRLIKKGETPVINNTQ
>NC_017297.1|WP_003359440.1|3876996_3877395_-|spore-cortex-biosynthesis-protein-YabQ
MVISISKQLGLLIFSFLSGLITGVFFDIYRSIRMDKNLSPIIKIIEDILFWCLAAIVIFIFLLYNDCAFIGVYVYLWIAIGLYIYIFFISKYLNPIFIYVVQNINKFFRISINIIVYPFKILIYKIKSNKMH
>NC_017297.1|WP_012101156.1|3877410_3877701_-|sporulation-protein-YabP
MEKKEFKNDDKISNLNLESRKRLILSGINEVISFNEQEIMLKTTLGDLDIKGSNLKMNKLDVQNGDVVIVGTINSCAYLNNESKANRSNIFSKLFK
>NC_017297.1|WP_012048379.1|3877820_3878060_-|RNA-binding-S4-domain-containing-protein
MRLDKFLKVSRIIKRRTVAKEACENERVFVNSKIAKPGTEVKEGDILEIQYANKTMKYEIISVLEHVKKEDAENMYKII
>NC_017297.1|WP_003359333.1|3878133_3878412_-|HU-family-DNA-binding-protein
MNKSELITSMAEKSKLTKKDAETALKAFIESVEEALEGGEKVQLVGFGTFETRERAERVGRNPRTKEEITIPASIAPVFKAGKELKEKVNKK
>NC_017297.1|WP_012101157.1|3878539_3879985_-|nucleoside-triphosphate-pyrophosphohydrolase
MINIIGLGPGSKESITLGTIDSLKTVDKVFLRTEKHPTVEYINKLGITYETFDGEYEVGESFDDVYNSIAKSLIEASKNYSDIIYAVPGHPLVAEKSVDILIKLCRQNDIKFKILPAVSFVDALMESLLLDPVEGLKIIDAFDIKKQAMDKRIGTIITQVYDKFIASEVKLNLMNYYKDDTEIFFVRAAGIEGLEEIRKIPLYELDRQHNIDHLTSVYIPKVPNNNYDFMDLLDIMDKLRGEDGCPWDREQTHVSLKKYLIEESYEVIEAIDNKDVDMLIEELGDVLLQVVFHSQIGKEDGFFEIKDVIQSICDKMINRHPHVFSDLEINNSSEVLENWDKIKSKEQGTETYTDSIRHIAKTLPALMRADKVQKKASKVGFDWDNIEDAMKKIIEEYKEIEDVYKSKNKVKILEEIGDLLFSVVNVARFLDIDPENALNYSIDKFINRFQYIEDEAISMGRQLDNMSLEEMDKLWKEAKNK
>NC_017297.1|WP_012101158.1|3879999_3881535_-|polysaccharide-biosynthesis-protein
MKKQSLIKGTFILGVAGIIAKFLGLFFRWPLQMLIGDEGIGYYQMSYPLYMFFIAAASGIPVAVSKLVSERNAVRDEGGIISVLKEAMIFMFIMGMGFTIILLLFSKDIIRFLKWDTRSYYSLIGISLAPLFISIMSVFRGFFQGMQNMNYTAISQLIEQLGRVIFGVGLAYILLPRGIEYSAGGAAIGAAAGGLLGGIYLFLKYLGVKKEFRVKKVKRNFKIMNTILYTAIPISIGSAVGTIMSLIDSALVPQKLLEAGFTYKQSTILYGQLTGKAFTLVNVPLTLSVSLCAALVPIIAEDYILNRRMAVLKKVELAIKISMVIAIPSCLGLNFMAKPILNLIFPGQEAGYEILKHLALSIPFIVLCQTSTAILQGIGRYIRPIINLCIGCILKIVITLILVPMNNINIYGAVIGTIAGYVISAILNMMALKKSLNISINYYEIMIKPLIASTIMIIAVVFIYFYAYNYTISSKIACLIAVFLGMIIYFIIIGLIGILDYNYIKRKIIKR
>NC_017297.1|WP_003495805.1|3881667_3882219_-|stage-V-sporulation-protein-T
MKATGIVRRIDDLGRVVIPKEIRRTLRIREGDPLEIFTDREGGVILKKYSPIGDLSEFSKGYTDSLQQTIGNIVMICDKDTIISISGAPKKEYLEKKISYDLEKIIEERKTVYFGDDNKAVSIYDDEDVDEKYSAQVISPIIAEGDTVGAVIIVSKEGGKKFNELEMKLAETASSFLGKQMEE
>NC_017297.1|WP_012101159.1|3882417_3883428_-|peptidylprolyl-isomerase
MKSAKKLLSVLCLGIFILTFTACDMVEKTPEAKAKSTIAKVNGEKIQRKDLDESPNMQQVLSQIKTQYGEEFEKTEQGKEVIKEQKKQILENLITEKVLLQKGKELKVIPKDEELNKEADKKVNEIKAVYNNDEKKFEETLKSTGFTKETLKEYLKDQIVIEKVINEVTKDVKVEDKDAQKYYNENQSMFTEKPNTMNVSHILVKTEDEAKKVKKRLDAKEDFAKVAKEVSQDTGSKEKGGLLGDISYSDSNYDPTFMKAAIALKSGEISNPVHTQWGYHIIKINSKKEYPVKKFDSVKEDIKKQLKQEKQQEAYTKKIEEWKKASKIKTYEKNLL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017297_14	14.1|2476181|30|NC_017297|CRT	2476181-2476210	30	NC_017297.1	2476157-2476186	0	1.0
NC_017297_14	14.2|2476229|30|NC_017297|CRT	2476229-2476258	30	NC_017297.1	2476157-2476186	1	0.967
NC_017297_14	14.4|2476313|18|NC_017297|CRT	2476313-2476330	18	NC_017297.1	2198240-2198257	1	0.944

1. spacer 14.1|2476181|30|NC_017297|CRT matches to position: 2476157-2476186, mismatch: 0, identity: 1.0

tctgcatcttctttcacattctcttctgca	CRISPR spacer
tctgcatcttctttcacattctcttctgca	Protospacer
******************************

2. spacer 14.2|2476229|30|NC_017297|CRT matches to position: 2476157-2476186, mismatch: 1, identity: 0.967

tctacatcttctttcacattctcttctgca	CRISPR spacer
tctgcatcttctttcacattctcttctgca	Protospacer
***.**************************

3. spacer 14.4|2476313|18|NC_017297|CRT matches to position: 2198240-2198257, mismatch: 1, identity: 0.944

tctacatcttcttctgca	CRISPR spacer
tctacttcttcttctgca	Protospacer
***** ************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017297_6	6.1|2352711|36|NC_017297|CRISPRCasFinder,CRT	2352711-2352746	36	NZ_CP013848	Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence	37322-37357	1	0.972
NC_017297_6	6.4|2352713|36|NC_017297|PILER-CR	2352713-2352748	36	NZ_CP013848	Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence	37322-37357	1	0.972
NC_017297_13	13.1|2382787|32|NC_017297|CRISPRCasFinder	2382787-2382818	32	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	64680-64711	1	0.969
NC_017297_13	13.1|2382787|32|NC_017297|CRISPRCasFinder	2382787-2382818	32	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	66917-66948	1	0.969
NC_017297_13	13.1|2382787|32|NC_017297|CRISPRCasFinder	2382787-2382818	32	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	77633-77664	1	0.969
NC_017297_13	13.1|2382787|32|NC_017297|CRISPRCasFinder	2382787-2382818	32	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	110118-110149	1	0.969
NC_017297_7	7.1|2359520|35|NC_017297|CRT	2359520-2359554	35	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	163657-163691	2	0.943
NC_017297_7	7.1|2359520|35|NC_017297|CRT	2359520-2359554	35	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	165473-165507	2	0.943
NC_017297_7	7.1|2359520|35|NC_017297|CRT	2359520-2359554	35	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	176189-176223	2	0.943
NC_017297_7	7.1|2359520|35|NC_017297|CRT	2359520-2359554	35	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	209081-209115	2	0.943
NC_017297_7	7.5|2359520|37|NC_017297|CRISPRCasFinder	2359520-2359556	37	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	163655-163691	3	0.919
NC_017297_7	7.5|2359520|37|NC_017297|CRISPRCasFinder	2359520-2359556	37	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	165471-165507	3	0.919
NC_017297_7	7.5|2359520|37|NC_017297|CRISPRCasFinder	2359520-2359556	37	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	176187-176223	3	0.919
NC_017297_7	7.5|2359520|37|NC_017297|CRISPRCasFinder	2359520-2359556	37	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	209079-209115	3	0.919
NC_017297_12	12.1|2376552|39|NC_017297|CRISPRCasFinder	2376552-2376590	39	NC_010379	Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence	39752-39790	3	0.923
NC_017297_12	12.1|2376552|39|NC_017297|CRISPRCasFinder	2376552-2376590	39	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	172657-172695	3	0.923
NC_017297_12	12.1|2376552|39|NC_017297|CRISPRCasFinder	2376552-2376590	39	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	117209-117247	3	0.923
NC_017297_12	12.1|2376552|39|NC_017297|CRISPRCasFinder	2376552-2376590	39	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	124443-124481	3	0.923
NC_017297_12	12.1|2376552|39|NC_017297|CRISPRCasFinder	2376552-2376590	39	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	264936-264974	3	0.923
NC_017297_9	9.4|2360700|36|NC_017297|CRT	2360700-2360735	36	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	64404-64439	4	0.889
NC_017297_9	9.4|2360700|36|NC_017297|CRT	2360700-2360735	36	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	66641-66676	4	0.889
NC_017297_9	9.4|2360700|36|NC_017297|CRT	2360700-2360735	36	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	77357-77392	4	0.889
NC_017297_9	9.4|2360700|36|NC_017297|CRT	2360700-2360735	36	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	109842-109877	4	0.889
NC_017297_12	12.1|2376552|39|NC_017297|CRISPRCasFinder	2376552-2376590	39	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	246041-246079	4	0.897
NC_017297_14	14.1|2476181|30|NC_017297|CRT	2476181-2476210	30	NZ_CP010418	Azotobacter chroococcum NCIMB 8003 plasmid pAcX50c, complete sequence	54261-54290	4	0.867
NC_017297_14	14.2|2476229|30|NC_017297|CRT	2476229-2476258	30	NZ_CP010418	Azotobacter chroococcum NCIMB 8003 plasmid pAcX50c, complete sequence	54261-54290	5	0.833
NC_017297_9	9.11|2360700|38|NC_017297|CRISPRCasFinder	2360700-2360737	38	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	64404-64441	6	0.842
NC_017297_9	9.11|2360700|38|NC_017297|CRISPRCasFinder	2360700-2360737	38	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	66641-66678	6	0.842
NC_017297_9	9.11|2360700|38|NC_017297|CRISPRCasFinder	2360700-2360737	38	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	77357-77394	6	0.842
NC_017297_9	9.11|2360700|38|NC_017297|CRISPRCasFinder	2360700-2360737	38	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	109842-109879	6	0.842
NC_017297_5	5.2|2352229|35|NC_017297|CRISPRCasFinder	2352229-2352263	35	NZ_MK275623	Clostridium perfringens strain JXJA17 plasmid p5, complete sequence	27329-27363	8	0.771
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_CP050860	Klebsiella pneumoniae strain SCH6109 plasmid pSCH6109-Vir, complete sequence	223011-223042	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_KY565557	Escherichia coli strain Mcp0221 plasmid pMcp0221, complete sequence	10287-10318	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	CP043017	Escherichia coli strain 388808_gen plasmid unnamed2, complete sequence	11824-11855	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_CP035776	Klebsiella pneumoniae strain R46 plasmid pR46-270, complete sequence	48808-48839	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_CP038334	Escherichia coli O157:H7 strain N8B7-2 plasmid pN8B7-2	39354-39385	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	CP019690	Shigella sonnei strain 75/02 plasmid p75-02_2, complete sequence	33639-33670	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_CP041094	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed2, complete sequence	21223-21254	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_CP024459	Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617aac, complete sequence	204870-204901	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	MN824002	Klebsiella pneumoniae strain N201205880 plasmid p205880-2FIIK, complete sequence	137673-137704	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	MK649826	Klebsiella pneumoniae strain 130411-38618 plasmid p130411-38618_1, complete sequence	22417-22448	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	MK649827	Klebsiella pneumoniae strain 1675474 plasmid p1675474_1, complete sequence	116259-116290	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	MK649828	Klebsiella pneumoniae strain 1675479 plasmid p1675479_1, complete sequence	21815-21846	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	MK649829	Klebsiella pneumoniae strain 16114547 plasmid p16114547_1, complete sequence	21815-21846	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_CP047635	Klebsiella pneumoniae strain K2606 plasmid unnamed2, complete sequence	22417-22448	8	0.75
NC_017297_7	7.11|2359717|32|NC_017297|PILER-CR	2359717-2359748	32	NZ_KY853650	Escherichia coli strain 347-43491A plasmid p977565, complete sequence	10035-10066	8	0.75
NC_017297_14	14.1|2476181|30|NC_017297|CRT	2476181-2476210	30	NC_021536	Synechococcus phage S-IOM18 genomic sequence	119897-119926	8	0.733
NC_017297_14	14.2|2476229|30|NC_017297|CRT	2476229-2476258	30	NZ_KT601170	Staphylococcus sciuri strain wo28-3 plasmid pwo28-3, complete sequence	25244-25273	8	0.733
NC_017297_14	14.2|2476229|30|NC_017297|CRT	2476229-2476258	30	NZ_KX982169	Staphylococcus sciuri strain wo27-9 plasmid pWo27-9, complete sequence	34158-34187	8	0.733
NC_017297_14	14.2|2476229|30|NC_017297|CRT	2476229-2476258	30	NZ_KX982171	Staphylococcus sciuri strain wo28-1 plasmid pWo28-1, complete sequence	38466-38495	8	0.733
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_CP050860	Klebsiella pneumoniae strain SCH6109 plasmid pSCH6109-Vir, complete sequence	223011-223044	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_CP035776	Klebsiella pneumoniae strain R46 plasmid pR46-270, complete sequence	48806-48839	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_CP041094	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed2, complete sequence	21221-21254	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_CP024459	Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617aac, complete sequence	204868-204901	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	MN824002	Klebsiella pneumoniae strain N201205880 plasmid p205880-2FIIK, complete sequence	137673-137706	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	MK649826	Klebsiella pneumoniae strain 130411-38618 plasmid p130411-38618_1, complete sequence	22415-22448	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	MK649827	Klebsiella pneumoniae strain 1675474 plasmid p1675474_1, complete sequence	116257-116290	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	MK649828	Klebsiella pneumoniae strain 1675479 plasmid p1675479_1, complete sequence	21813-21846	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	MK649829	Klebsiella pneumoniae strain 16114547 plasmid p16114547_1, complete sequence	21813-21846	9	0.735
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_CP047635	Klebsiella pneumoniae strain K2606 plasmid unnamed2, complete sequence	22415-22448	9	0.735
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	AP013386	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C23-MedDCM-OCT-S37-C51	34426-34459	9	0.735
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	GU943014	Uncultured phage MedDCM-OCT-S04-C1161 genomic sequence	18218-18251	9	0.735
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	GU943013	Uncultured phage MedDCM-OCT-S04-C1035 genomic sequence	11891-11924	9	0.735
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	GU943017	Uncultured phage MedDCM-OCT-S04-C1227 genomic sequence	7844-7877	9	0.735
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	GU943022	Uncultured phage MedDCM-OCT-S04-C890 genomic sequence	7790-7823	9	0.735
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	CP013001	Bacillus thuringiensis strain XL6 plasmid, complete sequence	131053-131086	9	0.735
NC_017297_14	14.1|2476181|30|NC_017297|CRT	2476181-2476210	30	NZ_KT601170	Staphylococcus sciuri strain wo28-3 plasmid pwo28-3, complete sequence	25244-25273	9	0.7
NC_017297_14	14.1|2476181|30|NC_017297|CRT	2476181-2476210	30	NZ_KX982169	Staphylococcus sciuri strain wo27-9 plasmid pWo27-9, complete sequence	34158-34187	9	0.7
NC_017297_14	14.1|2476181|30|NC_017297|CRT	2476181-2476210	30	NZ_KX982171	Staphylococcus sciuri strain wo28-1 plasmid pWo28-1, complete sequence	38466-38495	9	0.7
NC_017297_3	3.2|1903512|40|NC_017297|CRISPRCasFinder	1903512-1903551	40	NC_018689	Bacillus thuringiensis MC28 plasmid pMC429, complete sequence	417214-417253	10	0.75
NC_017297_5	5.1|2352164|35|NC_017297|CRISPRCasFinder	2352164-2352198	35	NC_008259	Enterococcus faecium plasmid pCIZ2, complete sequence	1636-1670	10	0.714
NC_017297_7	7.2|2359585|36|NC_017297|CRT	2359585-2359620	36	AP013386	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C23-MedDCM-OCT-S37-C51	34426-34461	10	0.722
NC_017297_7	7.2|2359585|36|NC_017297|CRT	2359585-2359620	36	GU943014	Uncultured phage MedDCM-OCT-S04-C1161 genomic sequence	18218-18253	10	0.722
NC_017297_7	7.2|2359585|36|NC_017297|CRT	2359585-2359620	36	GU943013	Uncultured phage MedDCM-OCT-S04-C1035 genomic sequence	11891-11926	10	0.722
NC_017297_7	7.2|2359585|36|NC_017297|CRT	2359585-2359620	36	GU943017	Uncultured phage MedDCM-OCT-S04-C1227 genomic sequence	7842-7877	10	0.722
NC_017297_7	7.2|2359585|36|NC_017297|CRT	2359585-2359620	36	GU943022	Uncultured phage MedDCM-OCT-S04-C890 genomic sequence	7788-7823	10	0.722
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_KY565557	Escherichia coli strain Mcp0221 plasmid pMcp0221, complete sequence	10287-10320	10	0.706
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	CP043017	Escherichia coli strain 388808_gen plasmid unnamed2, complete sequence	11824-11857	10	0.706
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_CP038334	Escherichia coli O157:H7 strain N8B7-2 plasmid pN8B7-2	39352-39385	10	0.706
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	CP019690	Shigella sonnei strain 75/02 plasmid p75-02_2, complete sequence	33637-33670	10	0.706
NC_017297_7	7.4|2359716|34|NC_017297|CRT	2359716-2359749	34	NZ_KY853650	Escherichia coli strain 347-43491A plasmid p977565, complete sequence	10033-10066	10	0.706
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	KC821626	Cellulophaga phage phi39:1, complete genome	23600-23633	10	0.706
NC_017297_7	7.9|2359586|34|NC_017297|PILER-CR	2359586-2359619	34	MG543995	Staphylococcus phage UPMK_1, partial genome	138793-138826	10	0.706
NC_017297_13	13.1|2382787|32|NC_017297|CRISPRCasFinder	2382787-2382818	32	MF979562	Pectobacterium phage DU_PP_III, complete genome	7298-7329	10	0.688

1. spacer 6.1|2352711|36|NC_017297|CRISPRCasFinder,CRT matches to NZ_CP013848 (Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence) position: , mismatch: 1, identity: 0.972

acataatcagatgttagaagtacttcacgaattaag	CRISPR spacer
acataatcagatgttagaagtacttcaggaattaag	Protospacer
*************************** ********

2. spacer 6.4|2352713|36|NC_017297|PILER-CR matches to NZ_CP013848 (Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence) position: , mismatch: 1, identity: 0.972

acataatcagatgttagaagtacttcacgaattaag	CRISPR spacer
acataatcagatgttagaagtacttcaggaattaag	Protospacer
*************************** ********

3. spacer 13.1|2382787|32|NC_017297|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 1, identity: 0.969

taattatcattataaaaaccctcatccatatg	CRISPR spacer
taattatcattataaaaatcctcatccatatg	Protospacer
******************.*************

4. spacer 13.1|2382787|32|NC_017297|CRISPRCasFinder matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 1, identity: 0.969

taattatcattataaaaaccctcatccatatg	CRISPR spacer
taattatcattataaaaatcctcatccatatg	Protospacer
******************.*************

5. spacer 13.1|2382787|32|NC_017297|CRISPRCasFinder matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 1, identity: 0.969

taattatcattataaaaaccctcatccatatg	CRISPR spacer
taattatcattataaaaatcctcatccatatg	Protospacer
******************.*************

6. spacer 13.1|2382787|32|NC_017297|CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 1, identity: 0.969

taattatcattataaaaaccctcatccatatg	CRISPR spacer
taattatcattataaaaatcctcatccatatg	Protospacer
******************.*************

7. spacer 7.1|2359520|35|NC_017297|CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 2, identity: 0.943

atagatgaaatagaaatagttatagatttaattga	CRISPR spacer
atagatgaaattcaaatagttatagatttaattga	Protospacer
***********  **********************

8. spacer 7.1|2359520|35|NC_017297|CRT matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 2, identity: 0.943

atagatgaaatagaaatagttatagatttaattga	CRISPR spacer
atagatgaaattcaaatagttatagatttaattga	Protospacer
***********  **********************

9. spacer 7.1|2359520|35|NC_017297|CRT matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 2, identity: 0.943

atagatgaaatagaaatagttatagatttaattga	CRISPR spacer
atagatgaaattcaaatagttatagatttaattga	Protospacer
***********  **********************

10. spacer 7.1|2359520|35|NC_017297|CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 2, identity: 0.943

atagatgaaatagaaatagttatagatttaattga	CRISPR spacer
atagatgaaattcaaatagttatagatttaattga	Protospacer
***********  **********************

11. spacer 7.5|2359520|37|NC_017297|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 3, identity: 0.919

atagatgaaatagaaatagttatagatttaattgaat	CRISPR spacer
atagatgaaattcaaatagttatagatttaattgaag	Protospacer
***********  *********************** 

12. spacer 7.5|2359520|37|NC_017297|CRISPRCasFinder matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 3, identity: 0.919

atagatgaaatagaaatagttatagatttaattgaat	CRISPR spacer
atagatgaaattcaaatagttatagatttaattgaag	Protospacer
***********  *********************** 

13. spacer 7.5|2359520|37|NC_017297|CRISPRCasFinder matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 3, identity: 0.919

atagatgaaatagaaatagttatagatttaattgaat	CRISPR spacer
atagatgaaattcaaatagttatagatttaattgaag	Protospacer
***********  *********************** 

14. spacer 7.5|2359520|37|NC_017297|CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 3, identity: 0.919

atagatgaaatagaaatagttatagatttaattgaat	CRISPR spacer
atagatgaaattcaaatagttatagatttaattgaag	Protospacer
***********  *********************** 

15. spacer 12.1|2376552|39|NC_017297|CRISPRCasFinder matches to NC_010379 (Clostridium botulinum B1 str. Okra plasmid pCLD, complete sequence) position: , mismatch: 3, identity: 0.923

ttattgcctatatgatagacgaagattatagattcttat	CRISPR spacer
atattgcctatatgatagacgaagattatagattctttg	Protospacer
 ************************************  

16. spacer 12.1|2376552|39|NC_017297|CRISPRCasFinder matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 3, identity: 0.923

ttattgcctatatgatagacgaagattatagattcttat	CRISPR spacer
atattgcctatatgatagacgaagattatagattctttg	Protospacer
 ************************************  

17. spacer 12.1|2376552|39|NC_017297|CRISPRCasFinder matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 3, identity: 0.923

ttattgcctatatgatagacgaagattatagattcttat	CRISPR spacer
atattgcctatatgatagacgaagattatagattctttg	Protospacer
 ************************************  

18. spacer 12.1|2376552|39|NC_017297|CRISPRCasFinder matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 3, identity: 0.923

ttattgcctatatgatagacgaagattatagattcttat	CRISPR spacer
atattgcctatatgatagacgaagattatagattctttg	Protospacer
 ************************************  

19. spacer 12.1|2376552|39|NC_017297|CRISPRCasFinder matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 3, identity: 0.923

ttattgcctatatgatagacgaagattatagattcttat	CRISPR spacer
atattgcctatatgatagacgaagattatagattctttg	Protospacer
 ************************************  

20. spacer 9.4|2360700|36|NC_017297|CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 4, identity: 0.889

aggtgaagaaattggagatactttagaagcagtttg	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttg	Protospacer
 .*.****************************.***

21. spacer 9.4|2360700|36|NC_017297|CRT matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 4, identity: 0.889

aggtgaagaaattggagatactttagaagcagtttg	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttg	Protospacer
 .*.****************************.***

22. spacer 9.4|2360700|36|NC_017297|CRT matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 4, identity: 0.889

aggtgaagaaattggagatactttagaagcagtttg	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttg	Protospacer
 .*.****************************.***

23. spacer 9.4|2360700|36|NC_017297|CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 4, identity: 0.889

aggtgaagaaattggagatactttagaagcagtttg	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttg	Protospacer
 .*.****************************.***

24. spacer 12.1|2376552|39|NC_017297|CRISPRCasFinder matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 4, identity: 0.897

ttattgcctatatgatagacgaagattatagattcttat	CRISPR spacer
atattgcttatatgatagacgaagattatagattctttg	Protospacer
 ******.*****************************  

25. spacer 14.1|2476181|30|NC_017297|CRT matches to NZ_CP010418 (Azotobacter chroococcum NCIMB 8003 plasmid pAcX50c, complete sequence) position: , mismatch: 4, identity: 0.867

tctgcatcttctttcacattctctt-ctgca	CRISPR spacer
acggcatcttctttcatattctcttgctgc-	Protospacer
 * *************.******** **** 

26. spacer 14.2|2476229|30|NC_017297|CRT matches to NZ_CP010418 (Azotobacter chroococcum NCIMB 8003 plasmid pAcX50c, complete sequence) position: , mismatch: 5, identity: 0.833

tctacatcttctttcacattctctt-ctgca	CRISPR spacer
acggcatcttctttcatattctcttgctgc-	Protospacer
 * .************.******** **** 

27. spacer 9.11|2360700|38|NC_017297|CRISPRCasFinder matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 6, identity: 0.842

aggtgaagaaattggagatactttagaagcagtttgat	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttgtg	Protospacer
 .*.****************************.***  

28. spacer 9.11|2360700|38|NC_017297|CRISPRCasFinder matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 6, identity: 0.842

aggtgaagaaattggagatactttagaagcagtttgat	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttgtg	Protospacer
 .*.****************************.***  

29. spacer 9.11|2360700|38|NC_017297|CRISPRCasFinder matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 6, identity: 0.842

aggtgaagaaattggagatactttagaagcagtttgat	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttgtg	Protospacer
 .*.****************************.***  

30. spacer 9.11|2360700|38|NC_017297|CRISPRCasFinder matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 6, identity: 0.842

aggtgaagaaattggagatactttagaagcagtttgat	CRISPR spacer
tagcgaagaaattggagatactttagaagcagcttgtg	Protospacer
 .*.****************************.***  

31. spacer 5.2|2352229|35|NC_017297|CRISPRCasFinder matches to NZ_MK275623 (Clostridium perfringens strain JXJA17 plasmid p5, complete sequence) position: , mismatch: 8, identity: 0.771

gagaatgtatttaagaatacaataaatgaatacaa	CRISPR spacer
atggaagaagttaataatacaataaataaatacaa	Protospacer
. *.* * * **** ************.*******

32. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_CP050860 (Klebsiella pneumoniae strain SCH6109 plasmid pSCH6109-Vir, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

33. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_KY565557 (Escherichia coli strain Mcp0221 plasmid pMcp0221, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgat	Protospacer
**.********* *********** *. *...

34. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to CP043017 (Escherichia coli strain 388808_gen plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgat	Protospacer
**.********* *********** *. *...

35. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_CP035776 (Klebsiella pneumoniae strain R46 plasmid pR46-270, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

36. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_CP038334 (Escherichia coli O157:H7 strain N8B7-2 plasmid pN8B7-2) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgat	Protospacer
**.********* *********** *. *...

37. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to CP019690 (Shigella sonnei strain 75/02 plasmid p75-02_2, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgat	Protospacer
**.********* *********** *. *...

38. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_CP041094 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

39. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_CP024459 (Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617aac, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

40. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to MN824002 (Klebsiella pneumoniae strain N201205880 plasmid p205880-2FIIK, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

41. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to MK649826 (Klebsiella pneumoniae strain 130411-38618 plasmid p130411-38618_1, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

42. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to MK649827 (Klebsiella pneumoniae strain 1675474 plasmid p1675474_1, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

43. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to MK649828 (Klebsiella pneumoniae strain 1675479 plasmid p1675479_1, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

44. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to MK649829 (Klebsiella pneumoniae strain 16114547 plasmid p16114547_1, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

45. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_CP047635 (Klebsiella pneumoniae strain K2606 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaaca	Protospacer
*** **************** *** *   *  

46. spacer 7.11|2359717|32|NC_017297|PILER-CR matches to NZ_KY853650 (Escherichia coli strain 347-43491A plasmid p977565, complete sequence) position: , mismatch: 8, identity: 0.75

ataataaatatgcatgtgaatatgtacttagc	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgat	Protospacer
**.********* *********** *. *...

47. spacer 14.1|2476181|30|NC_017297|CRT matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 8, identity: 0.733

tctgcatcttctttcacattctcttctgca	CRISPR spacer
actgcatcttctttcacaatttctaccagt	Protospacer
 ***************** *.*** *..  

48. spacer 14.2|2476229|30|NC_017297|CRT matches to NZ_KT601170 (Staphylococcus sciuri strain wo28-3 plasmid pwo28-3, complete sequence) position: , mismatch: 8, identity: 0.733

tctacatcttctttcacattctcttctgca	CRISPR spacer
gtaacatcttctttcacattttctttatta	Protospacer
 . *****************.****.  .*

49. spacer 14.2|2476229|30|NC_017297|CRT matches to NZ_KX982169 (Staphylococcus sciuri strain wo27-9 plasmid pWo27-9, complete sequence) position: , mismatch: 8, identity: 0.733

tctacatcttctttcacattctcttctgca	CRISPR spacer
gtaacatcttctttcacattttctttatta	Protospacer
 . *****************.****.  .*

50. spacer 14.2|2476229|30|NC_017297|CRT matches to NZ_KX982171 (Staphylococcus sciuri strain wo28-1 plasmid pWo28-1, complete sequence) position: , mismatch: 8, identity: 0.733

tctacatcttctttcacattctcttctgca	CRISPR spacer
gtaacatcttctttcacattttctttatta	Protospacer
 . *****************.****.  .*

51. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_CP050860 (Klebsiella pneumoniae strain SCH6109 plasmid pSCH6109-Vir, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

52. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_CP035776 (Klebsiella pneumoniae strain R46 plasmid pR46-270, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

53. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_CP041094 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

54. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_CP024459 (Klebsiella pneumoniae strain QS17-0161 plasmid pMR0617aac, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

55. spacer 7.4|2359716|34|NC_017297|CRT matches to MN824002 (Klebsiella pneumoniae strain N201205880 plasmid p205880-2FIIK, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

56. spacer 7.4|2359716|34|NC_017297|CRT matches to MK649826 (Klebsiella pneumoniae strain 130411-38618 plasmid p130411-38618_1, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

57. spacer 7.4|2359716|34|NC_017297|CRT matches to MK649827 (Klebsiella pneumoniae strain 1675474 plasmid p1675474_1, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

58. spacer 7.4|2359716|34|NC_017297|CRT matches to MK649828 (Klebsiella pneumoniae strain 1675479 plasmid p1675479_1, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

59. spacer 7.4|2359716|34|NC_017297|CRT matches to MK649829 (Klebsiella pneumoniae strain 16114547 plasmid p16114547_1, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

60. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_CP047635 (Klebsiella pneumoniae strain K2606 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atactaaatatgcatgtgaagatggaaaaacact	Protospacer
*** **************** *** *   *  .*

61. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to AP013386 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C23-MedDCM-OCT-S37-C51) position: , mismatch: 9, identity: 0.735

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgac	Protospacer
.  ******* ***************.**.  *.

62. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to GU943014 (Uncultured phage MedDCM-OCT-S04-C1161 genomic sequence) position: , mismatch: 9, identity: 0.735

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgac	Protospacer
.  ******* ***************.**.  *.

63. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to GU943013 (Uncultured phage MedDCM-OCT-S04-C1035 genomic sequence) position: , mismatch: 9, identity: 0.735

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgac	Protospacer
.  ******* ***************.**.  *.

64. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to GU943017 (Uncultured phage MedDCM-OCT-S04-C1227 genomic sequence) position: , mismatch: 9, identity: 0.735

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgac	Protospacer
.  ******* ***************.**.  *.

65. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to GU943022 (Uncultured phage MedDCM-OCT-S04-C890 genomic sequence) position: , mismatch: 9, identity: 0.735

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgac	Protospacer
.  ******* ***************.**.  *.

66. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to CP013001 (Bacillus thuringiensis strain XL6 plasmid, complete sequence) position: , mismatch: 9, identity: 0.735

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
tttaaagtagatgaaaaaggtaaattaattaaaa	Protospacer
 ****** **********.****** ..* * * 

67. spacer 14.1|2476181|30|NC_017297|CRT matches to NZ_KT601170 (Staphylococcus sciuri strain wo28-3 plasmid pwo28-3, complete sequence) position: , mismatch: 9, identity: 0.7

tctgcatcttctttcacattctcttctgca	CRISPR spacer
gtaacatcttctttcacattttctttatta	Protospacer
 . .****************.****.  .*

68. spacer 14.1|2476181|30|NC_017297|CRT matches to NZ_KX982169 (Staphylococcus sciuri strain wo27-9 plasmid pWo27-9, complete sequence) position: , mismatch: 9, identity: 0.7

tctgcatcttctttcacattctcttctgca	CRISPR spacer
gtaacatcttctttcacattttctttatta	Protospacer
 . .****************.****.  .*

69. spacer 14.1|2476181|30|NC_017297|CRT matches to NZ_KX982171 (Staphylococcus sciuri strain wo28-1 plasmid pWo28-1, complete sequence) position: , mismatch: 9, identity: 0.7

tctgcatcttctttcacattctcttctgca	CRISPR spacer
gtaacatcttctttcacattttctttatta	Protospacer
 . .****************.****.  .*

70. spacer 3.2|1903512|40|NC_017297|CRISPRCasFinder matches to NC_018689 (Bacillus thuringiensis MC28 plasmid pMC429, complete sequence) position: , mismatch: 10, identity: 0.75

tatttaaaggatttaaactta---catcatttagatttaagag	CRISPR spacer
tatttaaaggatttaaacttagttcattacataggttatc---	Protospacer
*********************   ***.*. ***.**      

71. spacer 5.1|2352164|35|NC_017297|CRISPRCasFinder matches to NC_008259 (Enterococcus faecium plasmid pCIZ2, complete sequence) position: , mismatch: 10, identity: 0.714

gtatcttctaagttttctgtattagatatttatgg	CRISPR spacer
attgcttccaagatttctgtattagatatgctttc	Protospacer
.*  ****.*** **************** . *  

72. spacer 7.2|2359585|36|NC_017297|CRT matches to AP013386 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C23-MedDCM-OCT-S37-C51) position: , mismatch: 10, identity: 0.722

gttaaagaagatgaaaaaagtaaataggtgatatta	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgacaa	Protospacer
.  ******* ***************.**.  *. *

73. spacer 7.2|2359585|36|NC_017297|CRT matches to GU943014 (Uncultured phage MedDCM-OCT-S04-C1161 genomic sequence) position: , mismatch: 10, identity: 0.722

gttaaagaagatgaaaaaagtaaataggtgatatta	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgacaa	Protospacer
.  ******* ***************.**.  *. *

74. spacer 7.2|2359585|36|NC_017297|CRT matches to GU943013 (Uncultured phage MedDCM-OCT-S04-C1035 genomic sequence) position: , mismatch: 10, identity: 0.722

gttaaagaagatgaaaaaagtaaataggtgatatta	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgacaa	Protospacer
.  ******* ***************.**.  *. *

75. spacer 7.2|2359585|36|NC_017297|CRT matches to GU943017 (Uncultured phage MedDCM-OCT-S04-C1227 genomic sequence) position: , mismatch: 10, identity: 0.722

gttaaagaagatgaaaaaagtaaataggtgatatta	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgacaa	Protospacer
.  ******* ***************.**.  *. *

76. spacer 7.2|2359585|36|NC_017297|CRT matches to GU943022 (Uncultured phage MedDCM-OCT-S04-C890 genomic sequence) position: , mismatch: 10, identity: 0.722

gttaaagaagatgaaaaaagtaaataggtgatatta	CRISPR spacer
aaaaaagaagttgaaaaaagtaaataagtatgacaa	Protospacer
.  ******* ***************.**.  *. *

77. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_KY565557 (Escherichia coli strain Mcp0221 plasmid pMcp0221, complete sequence) position: , mismatch: 10, identity: 0.706

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgatga	Protospacer
**.********* *********** *. *...  

78. spacer 7.4|2359716|34|NC_017297|CRT matches to CP043017 (Escherichia coli strain 388808_gen plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgatga	Protospacer
**.********* *********** *. *...  

79. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_CP038334 (Escherichia coli O157:H7 strain N8B7-2 plasmid pN8B7-2) position: , mismatch: 10, identity: 0.706

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgatga	Protospacer
**.********* *********** *. *...  

80. spacer 7.4|2359716|34|NC_017297|CRT matches to CP019690 (Shigella sonnei strain 75/02 plasmid p75-02_2, complete sequence) position: , mismatch: 10, identity: 0.706

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgatga	Protospacer
**.********* *********** *. *...  

81. spacer 7.4|2359716|34|NC_017297|CRT matches to NZ_KY853650 (Escherichia coli strain 347-43491A plasmid p977565, complete sequence) position: , mismatch: 10, identity: 0.706

ataataaatatgcatgtgaatatgtacttagctt	CRISPR spacer
atgataaatatgaatgtgaatatgaatatgatga	Protospacer
**.********* *********** *. *...  

82. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to KC821626 (Cellulophaga phage phi39:1, complete genome) position: , mismatch: 10, identity: 0.706

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
attaaacaagatggaaaaagtaaatttaagttta	Protospacer
.***** ******.***********  . * *  

83. spacer 7.9|2359586|34|NC_017297|PILER-CR matches to MG543995 (Staphylococcus phage UPMK_1, partial genome) position: , mismatch: 10, identity: 0.706

gttaaagaagatgaaaaaagtaaataggtgatat	CRISPR spacer
gacaaagaagatgaaaaaaataaagagaaaaatg	Protospacer
* .****************.**** **. .*   

84. spacer 13.1|2382787|32|NC_017297|CRISPRCasFinder matches to MF979562 (Pectobacterium phage DU_PP_III, complete genome) position: , mismatch: 10, identity: 0.688

taattatcattataaaaaccctcatccatatg	CRISPR spacer
gcgaggtcattataataacccgcatccatttt	Protospacer
  .  .********* ***** ******* * 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1733058 : 1741270	7	uncultured_phage(33.33%)	NA	NA
DBSCAN-SWA_2	1966595 : 2055534	80	Clostridium_phage(51.43%)	portal,tail,terminase,capsid,integrase,head,protease	attL 2010013:2010030|attR 2067214:2067231
DBSCAN-SWA_3	2528453 : 2588159	68	Clostridium_phage(63.04%)	tail,terminase,protease,portal	NA
DBSCAN-SWA_4	3093288 : 3102891	8	Synechococcus_phage(28.57%)	NA	NA
DBSCAN-SWA_5	3253962 : 3275563	27	Clostridium_phage(85.71%)	NA	NA
DBSCAN-SWA_6	3378914 : 3462532	85	Clostridium_phage(54.05%)	bacteriocin,holin,tail,terminase,capsid,tRNA,integrase,head,protease	attL 3416520:3416539|attR 3451774:3451793

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017297|1733058:1741270|DBSCAN-SWA
ACTATGTCATATTTGAATATATATCATTAATTTTTTTACATTTATTTTTTATAATTTCTCTAATATGATTGGGTTCAAGTACTTCCACATATTCTCCGTAACTTAATATCATGGAATATACCCAGTCATCTTCTAATAAATATGTATCTACAATTACACTACCATCTTCTTGAAACTTCATTTCATCTTTATCAAAAGAATCGTCTATTCTATATCTAACTCTTTCAGAAAACTTTAGTACAACTCTTGTAGGTACTTGTTCACTCTCACTAATATTTATATATTCTTTATAGGAAATTCTATTTTCATTAATTTTTTCATGTAAAACAGTTAAACTTTCCATTCTTGATAATTTGAAAAATCGGTAATCATTTTTTAATTTGCAAAAGGAAAATAAATACCATGAAAAACCTTTAAAAACAAGAGTTAATGGTTCTACCTGTCTCCAATTATATTCACCTTTTGAGTTTCTATAATCAAAGGCTATACAGTTTTTGTTATCTACAGCATCATATATAATTTTGTATTTTAAGTTTTCTTCTTCACATTTTTTAAAGCCCCAAGGTAATGTATCTATACACATTTGCTCAAAATGCAAATCAAATACTTCTTTTTTTTCTTTAGGAACAATATTTTTTACCTTTTCAATGGCCATTTCAACATTTTTATTATCTAAAAATTTATTCATATTTTTTAGAGCTTCTATAATTGAAATCATATCTTCTAATGTTAAAAGTTGATGATTGATTTTATAGTTATCTATAATATAAAATCCTCCATTATTTCCAATTTGAGAAACTATAGGAATTCCAGCAAGATTAATTGCTTCAATATCTCTATAAATTGTTCTTACAGAAACCTCAAATTTTTCAGCTAATTCTGATGCAGATATTTTTTCTTTATTTAAAAGCATTACAATAATTGCCAATAATCTATTAATTTTCATGAATCTATAAACCTCCCATAATTTGAAATGACTATTTTATTATATCAAATTAATAACTTGTAAAATTGGTTAGAGAGAAATTGCTGGGAGAACTGTATAAGAAAGTTTTAAAAAAATAAATTCCGGCATGGTAATTTTTGGGCTGTTTATGGGTATGAACTTGACTTAACAAATGTACTATAGTAAACTTATATCGTAAAAAAGAATAAAGACAGTTCGTAACCATCCTGTCTATAAATAAAACTAGGACGTAGCTACCGCCTTAGGTAGTTTTTTTGTTGATGGGCATTTAATGCCCTTTTTTATTTGCAAAAAATTTACAAATAGGATTTTTGTTTTAGGTGAAATTTTTAATTTATATAAAGTTTAGAAATTGTTATTCAAGGACGCAGAGGTCTTATCCAATGAATTTTTTAACTTAAATATAACAGTAACAATATAAGGCTGTTTTTTATAAAGATTGTCCAAATATAACTTAAAAACCTTACAAGGTAGGAAACTTTAAATAGTTGTAAAATATCCTAATAAATAATAATTTATCATAACCATTATAACTATTTGATGTTTTCAAGTCTAAGTGAGTGTAATAGATTGAAAAATCTATAGCACAAGGAGGAATGAAAATGAAAAAAATAGGACTAACAACTACAGTGCCAGTGGAAGTTATTGTTGCAGCAGGATATACACCAGTAGATTTAAATAATATGTTTATAACTTCAGAGAATTATTTAAAATATATAGACATAGCTGAAAGAGATGGTTTCCCCAAAAGCTTATGTGCTTGGATAAAGGGGATTTATGGAGCATGTCTAGAAAATAATATTAAAGAAATAGTTGGAGTTATGGAGGGGGATTGTTCTAATACTAAAGCTCTTATTGAGGTTTTTAAACTAAGAGGAATAAAAATTTATCCATTTTCATTTCCCCATAGCCATAGTTTAAAGGATGTAGAAATTGAAATAAGAAAGTTCATGGATATCTTCAATGTTAACGAGGATAAGGTAGAACAGGTTAGAAAAATATTAAATAGAGTTAGAAAGCTAGCAAAAAAAATAGATGAAATGACTTATATAGATAATAAGGTTAATGGTTTTGAAAACCATCTATATCAGGTGAGCTTAAGTGACTTTAATGGAAACATAGATGAATTTGAAGAACACCTTAAAAAAGTCATTGATGGTATGGAGAAAAGAGAGCCAATAAATAAAAAGTTAAGATTAGGCTATATAGGAGTTCCTCCAATGACTGGAGATATATATGAGTTTAGTGAAAAATTAAATGCTCATTTTGTATATAACGAAGTTCAAAGAGAATTTGCTTTTCCTAGGGGGATAGAAGCTGCAAATATATTTGAACAGTATTATAATTACACTTATCCTTATGATAATGAGTTTAGAATTAAGGAATTGAAAAAGCAAATAGAAAAGAGAAAGATAGATGCTATAATTCACTACACTCAGGCTTTTTGCCATAGAGCTGTTGAAGATATAGTATTAAAAGAAGAATTAAATATTCCTATGTTAAATATTGAAGGTGATAAGTTAAATACATTAGATGCAAGAACTAAACTAAGATTAGAAGCCTTTCTGGATATGTTGCTGGACTTAAAGCAGAAGTAATAGGTGATCTAGTAAGAATTTTTATCTTAATATATTGTTGGATTTAAAGCAAAAGTAATAGACGGTATATAAAAGAAGTTCATGTTTTCTTTATATTTAATGAAGGAGGGGAATTAATGAGATTGTTAGGAATAGACCTTGGAAGTAGAGAAGTTAAGATTGTTTTAATGGAAAACAATCTTATAGTTAAAAAGAAAAAAGTAAGTACCATGAAATTTTATAGAGATTACTGTAGCTTTCATGGCAAGATTGTAGTAGGTTTAGAAAAACTTAATATAGAAGGAATAGATAAAGCGATATCAACGGGTTATGGGAAAAATAATACGGATTTAGAATTTTTTACACCTATAAATGAGATAAAAGCCCATGTTTATGGTGGGATCTATCAAAGTAATTTAAAGGATTTTATTACTTTTAGATGTAGGTGGTCAGGACGTTAAGGTGGTAAAGGTAGAAAAGGGCGTTGCAACAGATTTGGAGCTTAATGAAAAATGTGCTGCTTCCTGTGGAAGATACTTGGAGAATATGGCAAATGTACTTGAAATATCCCTAGATGAAATGAGTCAGTACTCGGAAAATCCTGTGGATTTAAATTCCACCTGTGCAGTATTTTCTGAATCAGAATTAATTGGAAAAATAGCCGAAGGGGTACACATAGAAAGGTTATGTGCTGGGGTTAATTACTCTTTGTATAAAAGGCTACAACCTCTTTTAAGTAAGTTTAGGGGGAAGAAATTAGTTATAACCGGTGGTGTTGCAAATAACCATTCAATAAAAAAATATTTAAATAATGATTATGAAGAAATAGTATCCGTAAAAGATCCTCAGTTTAATGGGGCTATTGGATGTTGTTATTACGGAAGCAAATTTTTAAAATAAACTTAGGAGGAAAAAACATGTATACTTTAAAAGTAGAACATAATTTTGATAGCGCTCATTTTCTTGCAGGTTATGAAGGTAAATGTGGAAATATTCATGGACACAGATGGAAGGTTGAAATTCAGGTTCAGGCAGAATCATTAGTACAAGGCGGTCAACTTGACGGGATGATAATAGACTTTGGAGACTTAAAAAAAGATGTTAAATCTATGGTAGATTATTATGATCATGCACTTATAATAGAGAAAGGAACTATGAGGGGGCAATCATTAAGCTCATTAAAGGAGGATGGATTTCGTATAATAGAAGTTAATTTTAGACCAACAGCGGAAAATTTTGCAGCTTTTTTCTATAAAATTATGAAGGATAGAGGATATAATGTAAAAAGTACTACAGTTTATGAAACACCTAATAATAGTGCTACCTATGAAGAAAGTGGGGTAATTTAAAATGGATTTTAAGGTGGTTGAAAGTTTTATAAGCATAAATGGAGAAGGAAGGCGTTGTGGACAACTGGCTATATTCATAAGATTCGCGGGTTGTAATTTAAACTGTAGCTATTGTGATACACTTTGGGCAAATGAAAAGGATGTACCCTATGAAGTATTAAGTTCCAAAGATATATATGAATATATTAAGTCCAAAGAGGTTAAAAATGTAACTTTAACAGGAGGAGAACCTCTTTTGCAAAAGGGAATAATGGAGTTATTAAAACTTTTGTCTAAGGATAAAGAGCTTTATGTGGAAATTGAGACAAATGGCAGCATATTATTAGATGAATTTTTGAATATAGAAAATTCACCAAGCTTTACTATGGATTATAAACTTCCTTTAAGTAATATGGAAAATAAAATGGCATTAGATAACTTTAAATATTTAACTAAGAAGGATACAGTAAAATTTGTATCAGGTAGTATAGAGGATTTAGAAAAAGCTAGAGAAATAATAAATAAGTATAACTTAGTAGATAAAACTAATGTGTATATAAGTCCTGTTTTTGGAAAAATTAATTTAGATACTATTGTAGAATTTATGAAAAATAATAGAATGAATGGAGTTAATTTACAACTGCAGCTTCACAAGATTATATGGGAGCCTAGTAAGAGAGGAGTATAGTATATGGCAATTGATGTTAAAGCAATTGAAGAACACATAAGGGGGATTTTGATAGCTTTAGGAGACAACCCAGAAAGAGAAGGTCTAAAGAACACACCAAAACGTGTAGCTAAAATGTATGAAGAAGTATTCAAAGGTATGTGTTATAGCAATGATGAAATTGCAGAAATGTTTAATGTAACCTTTGAAGATGATTTATGTATAAATGATAATGAAAATGACATGGTTTTTATGAAGGAAATAGAGATATTTAGTCATTGTGAACATCATTTAGCACTTATGTACAATATGAAAGTAGCCATAGCATATATACCTAAGAAAAAAATTATTGGTTTAAGCAAAATAGCACGAATAGCAGATATGGTAGGACGTAGACTACAGCTTCAAGAGAGGATTGGAAGTGATATAGCAGAAATACTTCAGAAGGTAACTGACTCAGAAGATGTAGCTGTTATTATAGAAGGAGAACATGGCTGTATGACCACTAGAGGAATAAAGAAGCCAGGTACTAAAACTATAACAACTACATTAAGGGGAAAGTTTAACACAGATCCTATTGTAAGCAATAAATTAATGATGCTTTATACGAAATAAAGAAATTTTTAGTTCTAGTTAGAGTTTTATTAAAATAAATATATTAAATTCGTACAAGATTAAAAAATCTTACACATGAGTAGAACAGTTTATATAAAGAGAGTGTATTAAAGAAGCATAACTATAACAAAGATTTTTGTAGATTGTAGGATGATAATAAAATAATAAAGGGATGTGTAGTAGATGAATAAGGAAAAAGCAATAGTAGTATTTAGTGGTGGACAAGATAGTACAACCTGTTTGTTTTGGGCAAAGAAAAAATATAAAGAAGTTATAGCAGTATCCTTTGATTATAATCAAAAACATAAATTAGAGTTAGACTGTGCAAAGGATATATGTAAAAAATATAATATTGAACATCATATTTTAGATTTAAATTTGTTAAATCAATTAGCACCAAATTCACTAACTAGGCAGGATATAACTGTTGATAAAAGCGCACCTAAAGAAGGAGTGCCTAATTCCTTTGTAGATGGAAGAAATTTATTGTTTTTAAGCTTTGTCGCAGTATTTGCAAAACAAAAAGGAATAAACACTATTATAACTGGTGTGTCACAGAGTGATTTTAGTGGATATCCAGATTGTAGAGATGTATTTATAAAATCTTTAAATGTTACATTAAATTTAGCTATGGATTATGAATTTGAAATAATTACACCACTAATGTGGATTAATAAAGCAGAAACGTGGAAAATGGCTTATGATTTAGGAGTTCTTGATATAGTTAAAGAAGAAACCTTAACATGCTACAATGGAATAAAAGCGGATGGATGTGGGGAATGTCCAGCTTGTAAATTAAGAAAAAAGGGATATTTGGAGTTTGAGAAATATTTAATGAATTAGAGTTAATTTAGGAGGACTAGTATGCTAAGTACTAGTTTTTTTATTGTGAAATTATGGGGAATTATGGTATAATTAGTTCAGGATTAAGCAAGTTATTGTAAAGTTATGAAATTTTTACAGGGATTATAGCGATAATAATTATAGAGGGTTCTTTATTGTAAAGTTATAGTTATTTAAGAATAATAAAAAAAATCTACGCAAAGAGGAAATATCTTATAAAGAATCAAGTATATTAATTCTGCTTATATGGCAAAAAGTAACATGTTTTTATAAAGGACAGGAAGGTGAAGACTATGGAAAAATTTAATGAAAATAGGGGTATATCTATAAAAGAGAGTATTAAATTATTTTTTGAAATTAATATATGGTTAATTATATATGGAATTCCATTTACTATTTTGGCCATATATTTTAAAGAACATGGATTAGAAGTGACTTATGAATCTATTGAACAATTAGGAGAAATAGTAGCCTATATATTTATTATAAAAAAATATATAAAAGGTTTAAATTACAAGAAAATTTTAGATTTAAAATTAAATATAAACCTACATTAAAAGAAGGTATTTTTATAATCATAGCAACAATAGCATATATTTTTGTATATGATAATACTTTGGGGATATTGCTACAAAAAATCCCTGAAGCTGATTGGGTTAAGAATGCTTTTATTGAGATTGAAAGTGAACCTCTATTATTACAGTTTAGCTCATTGTGTTTAATTGCACCAATTTTTGAGGAAATAATATGTAGAGGAATAATATTAGAACAGTTAAATAAAAGATGTGGAGCTACAAAAGCTATATTAATTTCTTCATTATTTTTTGGCATAATGCACTTTAATTTGCATCAAGGAGTAAACGCGTTCTTCATAGGGGTAGTTATGGGAGTTATTTATGTTAAGACAGATTCATTGTTACTTACTATACTTTTGCATTTTGTAAATAATTTATATTGTTTAATAGCACAGTATATACCATATTTAGACCAGATTGAATCTAATTTTAGTGTAGTTAGATTAATATGTGGATCTATATTGCTTTTTATATCCTATAGATTTTTTAATGGTATAAAAATACATTTAAATAGAGAGCTTAATTTGAGATCTTAAAGTATATTTAAAAGATAAAAATAATTTAAAATAATAATTTTATATGTATTGCTTGAGCAATACTTCCTTTTTATATTTCGTATTTAGTTTTTGTAAATTTTGTCGATAATTTAATATTATAAGTATGAAATATTAGGAGGATTATATTATGATAAATATTTTTAGTAAAAAAGATAGTAAAAAGGATAATAAAAATGATACTATTGAGCAGGAAGTTATTGTTGAAGAAAAACATGAAGTTGAAACTATAGATACTATGAAATTTCTAAAAGAAATGACTATACAGATAGAGGGTATAATACAGCAGCATAATAAAGTTAATGGTGAACATGAAGTGCTTGAAAAATTAGCAAAACAGATTGAAAATCATATGGTAACAGTATCAAATTTAACTGAAAGGACTAATGAATCAACAGATAAGCTTTTTAGTCAAGGAGAAAGTCTGTTAGAGATTACAAAAGATACTGTAAATAAATCCTTAGAAGGTAAAAAGTCAATTGAGGGTATGGTTAAAGTGATTGAAAATCTTGACATAGAAACAAAGGATACATACGAGAATATTAATGCTTTGGGCGAAAAACTAAAGGAGATTGGAGAAATAGCTCAATTGATAAGTGGAATAGCCTCAAAAACAAATCTTCTTGCTCTTAATGCTGCCATAGAAGCAGCCCGTGCAGGAGAACAAGGCAAAGGCTTTGCAGTAGTTGCTGATGAAGTTAGAAAATTGGCAGAAATGACCGGTGAAAGCAGTAGTAATATAACTAATTTAATTAGTGGCATAGACTCACAAACTAAAAATGTTTTAAATAGTGTTGAAAAGAGTACATTAGTAGTTACAGAAGGAGTAAAATCCTCTAAAGGAGCCCTTGAAAAAATAGAAGAAGTTCTAGATTCATTTAACAGAGTTGAAGATGACACTGATAGCCTAATAAAAACAATTAATACTCAAAAAGAGGATATAAGTAAAATTTTTAACGGAATAAATGGAGTAGATAAAATTCTTACTGAAACCAATGAGCAAATTATAAAGCATATAGATGAGGCACACAAAGTAGATGAGAAATTAGAAAAAAGTGTATATCATATAGCTCAATATGTAAAATAA

Protein sequences of DBSCAN-SWA_1

>NC_017297|1733058:1741270|1736951_1737617_+|WP_012099659.1|DBSCAN-SWA
MDFKVVESFISINGEGRRCGQLAIFIRFAGCNLNCSYCDTLWANEKDVPYEVLSSKDIYEYIKSKEVKNVTLTGGEPLLQKGIMELLKLLSKDKELYVEIETNGSILLDEFLNIENSPSFTMDYKLPLSNMENKMALDNFKYLTKKDTVKFVSGSIEDLEKAREIINKYNLVDKTNVYISPVFGKINLDTIVEFMKNNRMNGVNLQLQLHKIIWEPSKRGV
>NC_017297|1733058:1741270|1734626_1735622_+|WP_012099657.1|DBSCAN-SWA
MKKIGLTTTVPVEVIVAAGYTPVDLNNMFITSENYLKYIDIAERDGFPKSLCAWIKGIYGACLENNIKEIVGVMEGDCSNTKALIEVFKLRGIKIYPFSFPHSHSLKDVEIEIRKFMDIFNVNEDKVEQVRKILNRVRKLAKKIDEMTYIDNKVNGFENHLYQVSLSDFNGNIDEFEEHLKKVIDGMEKREPINKKLRLGYIGVPPMTGDIYEFSEKLNAHFVYNEVQREFAFPRGIEAANIFEQYYNYTYPYDNEFRIKELKKQIEKRKIDAIIHYTQAFCHRAVEDIVLKEELNIPMLNIEGDKLNTLDARTKLRLEAFLDMLLDLKQK
>NC_017297|1733058:1741270|1736518_1736950_+|WP_011949100.1|DBSCAN-SWA
MYTLKVEHNFDSAHFLAGYEGKCGNIHGHRWKVEIQVQAESLVQGGQLDGMIIDFGDLKKDVKSMVDYYDHALIIEKGTMRGQSLSSLKEDGFRIIEVNFRPTAENFAAFFYKIMKDRGYNVKSTTVYETPNNSATYEESGVI
>NC_017297|1733058:1741270|1738394_1739054_+|WP_012099661.1|DBSCAN-SWA
MNKEKAIVVFSGGQDSTTCLFWAKKKYKEVIAVSFDYNQKHKLELDCAKDICKKYNIEHHILDLNLLNQLAPNSLTRQDITVDKSAPKEGVPNSFVDGRNLLFLSFVAVFAKQKGINTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYEFEIITPLMWINKAETWKMAYDLGVLDIVKEETLTCYNGIKADGCGECPACKLRKKGYLEFEKYLMN
>NC_017297|1733058:1741270|1740313_1741270_+|WP_012099663.1|DBSCAN-SWA
MINIFSKKDSKKDNKNDTIEQEVIVEEKHEVETIDTMKFLKEMTIQIEGIIQQHNKVNGEHEVLEKLAKQIENHMVTVSNLTERTNESTDKLFSQGESLLEITKDTVNKSLEGKKSIEGMVKVIENLDIETKDTYENINALGEKLKEIGEIAQLISGIASKTNLLALNAAIEAARAGEQGKGFAVVADEVRKLAEMTGESSSNITNLISGIDSQTKNVLNSVEKSTLVVTEGVKSSKGALEKIEEVLDSFNRVEDDTDSLIKTINTQKEDISKIFNGINGVDKILTETNEQIIKHIDEAHKVDEKLEKSVYHIAQYVK
>NC_017297|1733058:1741270|1733058_1734003_-|WP_012099656.1|DBSCAN-SWA
MKINRLLAIIVMLLNKEKISASELAEKFEVSVRTIYRDIEAINLAGIPIVSQIGNNGGFYIIDNYKINHQLLTLEDMISIIEALKNMNKFLDNKNVEMAIEKVKNIVPKEKKEVFDLHFEQMCIDTLPWGFKKCEEENLKYKIIYDAVDNKNCIAFDYRNSKGEYNWRQVEPLTLVFKGFSWYLFSFCKLKNDYRFFKLSRMESLTVLHEKINENRISYKEYINISESEQVPTRVVLKFSERVRYRIDDSFDKDEMKFQEDGSVIVDTYLLEDDWVYSMILSYGEYVEVLEPNHIREIIKNKCKKINDIYSNMT
>NC_017297|1733058:1741270|1737620_1738211_+|WP_012099660.1|DBSCAN-SWA
MAIDVKAIEEHIRGILIALGDNPEREGLKNTPKRVAKMYEEVFKGMCYSNDEIAEMFNVTFEDDLCINDNENDMVFMKEIEIFSHCEHHLALMYNMKVAIAYIPKKKIIGLSKIARIADMVGRRLQLQERIGSDIAEILQKVTDSEDVAVIIEGEHGCMTTRGIKKPGTKTITTTLRGKFNTDPIVSNKLMMLYTK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012099656.1|1733058_1734003_-	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	1.4e-14	31.6
WP_012099657.1|1734626_1735622_+	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
WP_011949100.1|1736518_1736950_+	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	4.0e-12	32.4
WP_012099659.1|1736951_1737617_+	putative 7-carboxy-7-deazaguanine synthase QueE	S4TZT1	uncultured_phage	1.0e-38	44.1
WP_012099660.1|1737620_1738211_+	GTP cyclohydrolase I FolE	S4U0J3	uncultured_phage	5.4e-44	52.8
WP_012099661.1|1738394_1739054_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.3e-59	51.2
WP_012099663.1|1740313_1741270_+	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.7e-16	33.5

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017297|1966595:2055534|DBSCAN-SWA
ATTATTTAAAATATTTTCCTTTCTTTCTAATTATAGATATTAGTTCATCAGAAATTTTATTCATATTAACTTTAAGCTCTTTACTGATTTCCAAAGTGTAATCTATATTAGAAACTTCAATAGCTAGAATGTATCCTTTTATTTCATTATAATAAAGTTTAACTAAGTCTATAAAACTATAGCTATGTTGGGTATATCCATTTTTATGTGATGTATAAGTATCTAGAGGTAATATTGTTATATCTCCTATTTTTTTACCATAGTATCCCGCATCTAATATAAATAAGAAATCCTCCTTTTTTATTCTTGAAAGGCAATATTCAAAATCAGTTTCTCCTATTATAAGATCTATATAATTTTCTTTTAAAAATCCCTCAATATTTTTAGCTATTTTTATGGCTATACCATCATCACCCATTAAAATATTTCCTATAGCAATAACTTTAATAGCTATACTAATACTTCAACTTTAACTGGTTCATTATTATTACTTATTAAATGGGTGGCACAGGAAATGCAAGGATCAAAAGAACGAATTATTCTTCCTATTTCTACGGGTTTTTCTATATTATCTATTTTTGAGCCTATTAAGGATTTTTCTCCTACACCTCTTATACCATTTGAATCCTTAGGAGATATATTCCAAGCTGTAGGAGTTATAATATTATAGTACTTTATAGTTTTATTCTCTATTTTTATAAAGTGTGATAAGGCTCCCCTAGTAGTATCTATAAGGCCTTCTCCAAAGGCGCTTTCTGGAATATTATATGCAGATTGATTATTAGATAGTAATTGAATTTTTTCTGATATATTATATAATATATTTATTATTTTTTTAGTTTCTAGAACACGGGCTATATTTCTATCCATAGAGGAATTGCCTCCGGTATATTCTCCTGCAATTTTTAATCGAGCTAAAGGACCTACTTCCATAGGTAAATCAGCATATCTAGGTGCTTTTACGAAACTATAAGCTCCTTCTTTTTTTAAATCTACAGTATATTCATTGTTCACAATGGGATTTTCTATTATAGTATCGCTTACATACCAAGCATAGCGAATGTTTTCTGTTATTTTATCTCTATCAAAATTTTCTACTTTATTATTTATTATTACTCCCGGTTTTACATAGCTTATATTTTTATCCTTATATTTATCAAATACACCAAAACTCATAAAATTCCCATAAGTGTTTCCAAGATTAAAATATTCAGGGTAATACTGAGCAATTATATTCATATCCTCTAACATATAGATATTTACAAATTTTTTTTATTGCCTTTAATATGGATTGTATTTTTGTCAATTTGTAAGAATCTATATTTACGGTAACCCCTCCTACGAAAATACCATGACTATGAGGTGCTTTACCTCCCAATACAGCTAAGGCTTCATGGGCTAACCTACTATATTTTATGCCCTCTTCATAATGGGAACTTATTCTTTCATTTAACTTTTTAGGCAATCTAAAGTCACTATATTCTTGAGGGTATATAGGTCTTATATTAGGTAGATTTACATAGCTTGGCACAGTAAAACAATAAAACTGCCTTAGGTGGTTTTGTATAAATTCAAATCCATGCATCATATCTCTTATATATATATCATTTATACTTGGAGTTATATTTAATGCATTTTCTAAAGCTAAAGTAGATGCTGTAGCATGGGCAGTAGAACATATGCCACATATTCTTTCAGTAAAATATATAGAATCTAAAGGAGGTCTTCCTTCTAACATTTTTTCAAAGCCTCTAAATAATAATCCGCTGGTTTCACCATCTATAATAATGTTATCTTCTACTTTTACCTTTATTTCTAAAAATCCACTAATCCTAGTTATAGGATCAATAGTAATAATCTTTCCCATAATGACCTCCCATTTTTATAATTCAAAATTTACTTAGTTATCTTAAGCATAAATAATTTAAACTAAAAAATTAATATACTTTATTCTTTTAACTATAGAAATTAATACCTAACAAAGGGTTCCATACCATCTGGAAATCTTTCTTGGGCACAGCCTATACAATTTGTGTTGTCTCCAATAGGCCAATTTACATAGCCATTCCATTTTCTTCTGGGGCAATCTGTTTTTGTAACAGGTCCTCTACAGCCTAACTTAAACATACATCCTTCTTCTCCAAATTTTTTTGCAAATATTCTTTTATCAAAAAAGCCTCTTCTTGTACAACTATCATGAATAGTTATTCCATAAAATAATATAGGTCTCCCTTTATTATCTAATTCTGGTTTACCATAAGTAACTAGATGAGCTAAAGTACCTACCACCCAGTCAGGATGACAAGGACACCCTGGTAATTTTATTACTTCTTTATTTATAACAGCTTCTACGCTTTTGCTACCAGAAGGATTAGGTCTAGCCGCAGAAATACCACCATAAGAAGAACAGGTTCCTACAGTTACCACATATCTTGCTTTTTCACCTGCCATTTTTATTGCTTCTAATGCGGTAACAGGTTTTCCTTTATAATTAGCAATAATGTTATAATAGCCATTTTCTCTAGTGGACACAGCTCCATCCACTAATAATATAAATTCTGTGTCTAAAGTATTTAAAAACTGTTCATAGGCAAATTCTCCTTCAGCTCCCATTAAAGAATTATTAAAAGTTAAATTAACTATATTTCTAAGTATATAAATAAGCCCTGGATTTTCTGCGTTCAAAAGAGAAATTATATTTCCAGAACAGCCTGTTACTTCTAACCATATAGCATTTATTTTTTTTGTTTTTTTATGATTAATTGATTCCATAGCTTCTCTGCAAAGGATTTTTGAAGTTGTATCTTTCCTTTCAATTAATGGGCAAAAGCTATTATTCATTACTCCTCCTAAAAATTTATTAATTACCATATAAAAAATATGCTCCAATAAATTATATAAATAAAAATTATTTATTATGCTATTGAAAAATGAATAAAGTTTGTACGGCTATATTAATAGTACTTAAAATTATTAATGATTATTAGAATTAATTAAGTTTTTTATTACATTATTGTAATGTTTCTGTAATATAAATAAATTTCTCTATGTCTTGTGAACATATATAATTCTATTCATAAAAGAAACGCTTAAAGGAGGTTTTATATTATGAATTTAGATGGTTTTAAATTAAAAATTATAGCAATGATACTTATGGTGTTAGATCATTTGCCTAAAGCTTTTAATAACACTCCAATATGGTTTGGATGGCTTGGTAGGTTGGTAGCTCCTATATTTTTCTTTTTTGTGGCAGAAGGATTTTTTCACACAAGGAGTAAGAGTAAATATTTAATAAGGTTATTTGGATGGGGCGCAATCATGTTTGCAGGATCATCAATATTAAATTATGCTCTACCAGGAAAGGAGCCTTTACAAAATAATATATTTTTATCCTTAGGATTATCAGTACTTTTGATGTGTATTATTGATTATACTAGAAAAAGTAAAAATTATAAATTTGGTATTCCGTTAGCTATTATAGTGAGTATAGTATCTTTGTTTACAGAAGCATCTTTTGATGGAGTATTAATGACTTTAGTTCTCTACTTTTTTAGAGAGGATAAAATTAAATTATCTATTGGATATATTTTAATTTCTTTATTTGAATTTATTATGGTTAGTGGTGAAGGGCTAACTTATTTGAATTTATTCGTATTAAATTACCAATGGTTAATGATTTTTGCTCTTCCTCTTATTCTTATGTATAACGGTGAAAGAGGACTAAACAATAAATTTATAAAATATATGTTTTATGCTTTTTATCCTATACATTTATGGATAATTACTATAATATCTCACTTTCTAAAATAATATAAAAAGGTTAGTACTTATACTGTATAATTGTAGATTTTACCCGTGGTGGTTATTTAATATCTACAATTATATTTTTATTTCTGATATAAAAATTAGGTAGGGTTAATATTTTTTTACTTAAAATATTAACCCTACTACATATAATAAATAAATAAAAATAAGTATTTAATATATATTAATATTATATTAGAAAAAACTTTAAAAAGCATTGTAGTTATATGAGTTTTTTTTGCATATAATGATAGTATAGGGATATAACAAAACCTAATTAGTGTTTACTTATGACTATACTAGGTGGTAAAATTATGGTATACTATAAAAAAATTCAAATTTCGTAGAAGTGGATGGCTACGGTGGTTGTACGTTTTCCACCTTGGGCTATAGATGATTTTTCATTATAGCTTAAGGGGGTGGTATTGGATATGCTAGAACTTTTAATAAAAGGAGTTTTTGTGATTTGTATTATTAGTTTAATATTGAAACACAATCCTTTTTATTTCCAATATAAAAATCAAGGTTAGATTTCTTGGTTTAGATATAGAAGTTGATAGCAAAGAGAAAAAGCACCCATCCTCCAAAGATTAGTGCTTTTTTCCTTGTTTAACATATTTATAAGTTAAAAATCCAATAGCCCTAAAACAACACCACTAAAGTGGGAAGCAGTTATACCAAATGATAATTCGGATTTCTGCTTAAAAACGTTCTAGGATCGGCTTAGTGTTCTCAGCACTGAGCCTTTTCTAATTAGAATTTTTAAAAACTTGGTTTTAAAGTTCTGTACTTCTCAGTTTGCCTGTGAATTTTACCTAATATATATTATAACAAAAATTATATAAAAATAAACATAATAACTTAATTAATATAAATATTTTATAACCATAAATATTATATTCATATACAGTACTTTCAGTACTATAAAAATTAAAAAATATATTTAGTACTTTTTATTAATGACCCTAAACTTTATTTATTATAAATCCAAAGAAATTATTACATAAATTCAAAAAATATAATAAAATTTTTGAACTGTATTCCATTGCTCTAGACATATATACTTGTAAATTTTTTTATTCAGTATATATTTATATTAATTATTTTCTATGAAACATAGATTTTATATTATCATTATATGTTATTAAGGGTACTTTTTCAATGATTTTATTGTAAATATAGTTAAATCATACATTAATATGTATCTTATTACAATTTATATAATTGTTTTGTAATAATTTTTTTGAAATAATTGTAATATATATAGATTAGTTTGAAAGATCAAATATATACAAAGTTTCATCTTTTATCTCTTTAAATTTAATATCTACTATAGCTTTTAACGTATCTAGTGATGTTATTACTCCCAGATTTCTTTCAATGGCTGCTCTTCTTATGTGGAAACCATCTCTCTTTGAATCATTACCTTTTGTAGGAGTGTTAACCACTAAATCAACTTCATCATTTTTAATTGTATCTATTATATTTGGACTCTCTTCTTTAAGCTTTCTAACTTGCTTAACTTCTATGCCTTCTTCCTTTAAAAGTTCAGCTGTTTTAGAAGTTGCTATAAACTTATATCCTAAACTGTGAAGTTTCTTTGCTATTGGTAAAAATTCTTCCTTATCATGATCATTTATAGTAGCAAGGACTGTTCCTTTTTCCTTTTTAATAGATATATTAGCTCCTATAAATCCCTTATACAACGCTTCATCTAAAGTTTTTCCTACACCTAAAACTTCTCCCGTAGACTTCATTTCAGGTCCTAAACATACTTCAACTCTTGGAAGCTTCTGAGTAGAGAATACTGGAACTTTTACAGAGATTAGCTCTGGCTCTTTATATACACCTACCCCATATCCTAAATCATTTAACTTTTCACCAAGCATTACTCTAGTTGCTATGTCTACTATAGGAACTTTACTTACTTTACTTATATATGGTACTGTTCTTGATGCTCTTGGATTAACTTCTATTACATAAAGATTTCCTTGAAACTCAATAAACTGTATATTTATCATACCTTTTATTCCTATTCCTAAAGCAAGCTTTTTAGTATATTCAAGTATTTTTTCTTTTATATCCTTGCTTACATTTTGAGTTGGATACATAGTTATACTATCACCTGAGTGTACTCCAGCTCTTTCTAAATGTTCCATTATACCTGGTATTAAAACATCTTCTCCATCAGATATAGCATCTACTTCTATTTCTCTTCCCATTAAGTATTTATCTATAAGTATTGGATTCTTCTTATCCTTTTGGAAAGCATTTGATAGATAGTATACAAGTTCTTTTTCATCATGAGTTATTTCCATTCCCTGCCCTCCAAGTACATAAGAAGGTCTTACAAGCACTGGGAATCCTAACTTTTTAGCTTCTTCTAATCCATCTTCTACAGACCAAATACCTTTACCTTTAGGTCTTGCTATTTTAAGTTTTTCTAATAGTTCATCAAACTTTTCTCTATCTTCTGCCATATCAATTTGATCTGCAGTAGTTCCAAGAGTTGGTATATTCTTTTCTTTTAGGAAGTTAGCAAGCTTTATAGCTGTTTGACCTCCAAACTGTAGAATTACACCATCAGGTTTTTCCTTTTCTACTATATTTAATACATCTTCTTCTGTAAGAGGTTCAAAATATAGTTTATCAGATACATCGAAATCCGTACTAACTGTTTCAGGGTTGTTATTTACTATTATTGTTTCTATGCCCAATTTTTTAAGAGCTTTTACACAATGTACTGAAGCATAGTCAAACTCTATTCCCTGGCCTATTCTTATTGGCCCTGAACCTATAACTATTACCTTTTTATTTTTACTAACTTCAACTTCATCATAAACATCATAAGTTGAGTAATAGTAAGGTGATAAGGCCTCAAATTCTCCACCGCAAGTATCAACCATTTTATAAATTGGATTTATTCTCCATATATTTCTAAGTCTATATATATCTTCCGGGCTTACCTTAAGCATGTCAGCTATACCTTTATCTGAAAAACCTTTTTTCTTTAATTTATATAACCATTCTTTATCTAAATCATCTATTTTACTAAGTCTTAATCTTTGTTCTTCTTCAACTATCCATCTGAATTTTTTTATAAAGAATTTATCTATACCTGTTATTTCAGCTACCTTATCCATTCTGTAATCACGTCTAAGCATTTCAGCTAGTGCAAATATTCGCTCATCATCTGGAGATATAACTCTAGTTTTTAATTCTTCTATGCTAAGTTCTCTAAACTTTTTATGCTCTAATGAATACTTTCCTATTTCTAATGAACGTGTTCCTTTTAAAAATGCAGCTTCAAAATTGCTCCCTATAGCCATTATTTCTCCTGTAGCCATCATCTTTGTACCTAAAACTCTATCTGCTCCTTGGAATTTATCAAAAGGCCACTTTGGAATTTTAACTACTACATAATCTAAAGAAGGTTCAAAGCAAGCATACGTTTTTTCAGTAACTGCATTTTTTATCTCATCTAGAGTATATCCTAAAGCTATTTTAGAAGCCACCTTTGCTATTGGATATCCTGTTGCCTTTGATGCTAATGCTGAGGAACGACTAACCCTTGGGTTTATTTCTATAACTGCATATTCAAAGGAATTTGGATTCAATGCAAATTGTACATTACATCCTCCCTTTATTCCTATTGAGTTTAGTATATTTATAGATGCACTTCTAAGCATTTGATATTCTTTATCAGATAAGGTTTGACTTGGTGCTACAACTATACTATCTCCAGTATGAATACCTACAGGATCTATATTTTCCATATTACATACAGTTATACAGTTTCCTCTGCTATCTCTCATTACTTCATATTCTATTTCTTTCCAACCCTTAACACTTTTCTCTAAAAGTACTTGGCCTATAGAACTTAGTTGAAGACCTAATGCAAGTATTTCATCTAACTCTTCTTCACTTTCAGCTATTCCGCCGCCAGTTCCCCCTAAAGTATAAGCTGGTCTAACTATAATTGGATATCCTATTTTATTTGCAAAATCTTTTCCATCTTCCATATCAGTTACAATTTCACTTTGTATAACAGGCTCATTTATTCTACTCATAACATTTCTGAATAACTCTCTATCTTCTCCTTCTTTTATGGATTCTATAGATGTACCTATTACATTAACTCCGTATTTTTTTAATATTCCTTTATCATAAAGCTCTACTGCTAAATTTAGTCCAGTTTGACCTCCCATTCCTGCAAGAAGACTATCTGGTCTTTCCTTAGCTATAACTTTTTCTACAAATTCCACTGTTAAAGGTTCTAAATAAACTTTATCTGCAACTTTTTTATCTGTCATTATTGTAGCAGGATTACTGTTTATAAGTACAACCTCTACTCCTTCTTCTTTTAATCCTTCACAAGCTTGTGTTCCTGAATAGTCAAACTCTGCTGCTTGACCTATAACTATTGGACCTGAACCTATAACTAAAACCTTTTTTATATCTTTATTTAATGGCATAACTGCTACCTCCTAAATTTCCTGTTCTTATAGTGCATATTTCATGAATTCATCAAATATATAGTCGCTGTCCTTTGAGCCTGGACATGCTTCTGGATGAAACTGAACTGAAAATATAGATAAATTTTTATGTTTCATTCCTTCTATAGTTCCATCATTTACGCTAATATGAGTTACTTCCATATCCTTTGGAAGTACATCCACAAAATATCCATGATTTTGTGAAGTTATATGCACCTTATTTTCTTTTAAGTCCTTAACAGGATGGTTACATCCTCTGTGACCAAATTTAAGTTCCGCTGTCTTTCCTCCTAAGCTTAGAGCTAGAAGTTGATGCCCTAAACATATTCCTACAATAGGCTTTTTACCTATAAGAACTTTTATATTTTCTATAACTTCTGTTAAATCTTCTGGGTCTCCAGGACCATTAGATAAAAATATCAAATCAGGATTTACCTTTAAAATTTCTTCTGCTTTTGTATTTGCTGGGAAAACTGTTACATTGCATCCTCTATTTAGGAAGGATCTTACAATATTTTGCTTTATACCAAAATCCATTATTGCAACATGCTTTCCTTTTCCTGACACTTCATATTTCTCTTTAACCGTAACTTTTTCTACTGCATCTTTATTTGAGAAATCTTTAAGTTTTTCTTTAACTTCTTCATATTCTATATCTTCTAAAGTTATTATACCTTTCATAGTTCCATTGCTTCTTAAAATCTTAGTTAAAGTTCTTGTATCTATTCCTTCTAATCCTATAACATTGTTTTGCTTTAGATAGTCTTCCAATTCTACTTCTGATCTGAAATTACTTGAAAAACTGCATTTTTCTCTAACTATAAATCCTCTAACCTTTGGTGATTTTGATTCCATATCTTCTAAATTTATACCATAGTTTCCTATTAGAGGATATGTCATTGTAACAATCTGACCATAATAGGATGGGTCTGTAAGAATTTCTTGATACCCTGTCATTCCAGTGTTGAATACAACCTCTCCGACACTTTCCTTTAGACATCCAAATGCGTTTCCTTTAAATTTTACTCCATTTTCTAATATAAGCTTTGCTTTCATAAGTGGCCCCCTTTTATTTTTTCAGTAAAAATACACTTTGCAAGGGCTAAACCTAATTTTTAAAACAAAAGGGAAATAAAAAGATTTATGTCAAAAAATAATCTTTTTATTTCCCTTTATATAAATTTTATTTAAATTTAAACCTTTTTTTGCATCACAAAAAAATTCTTTCATAATTATCATACCTCTTTCTGGTCTCACAGGACCAATTTAAAGTGTATTCTTTACTTTAATTTTTTTTATTAATCATTATAATTTATAATTTTTAATCTGTCAATGTATAATACAGGTTTTATTTATCATCTATAAATTCTCCTGATTTATCAGTATTTAATATACCCTTATATTGTTAAAAATTTGTTTATTTTTTAACTTATGACTATACTAGCTGGTAAAATTATGTTATACTATAAAAGTAAAAATTTTCAAATTCCGTAGAAGTGGATGGCTACGGTGGTTGTACGTTTTCCGCCTTGGGCTATGGATGATTTTTCATTATAGCTTAAGGGGGTGGTATTGGATATGCTAGAACTTTTAATAAAAGGAGTTTTTGTTGTTTATATTATTAATTTAATATTAAAACATAACCTTTTTATTTCCAATATAAAAATCAAGGTTAGATTTCTTGGTTTAGATATAGAAGTTGATAGCAAAGAGAAAAAGCACCCATCCTCCAAAGATTAGTGCTTTTTTCCTTGTTTAACATATTTATAAGTTAAAAATCCAATAGCCCTAAAACAACACCACTAAAGTGGGAAGCAGTTATACCAAATGATAATTCGGATTTCTGCTTAAAAACGTTCTAGGATCGGCTTAGTGTTCTCAGCACTAAGCCTTTTCTAATTAGGATTTTTAAAAGCTTGTATTTCTAAGCTTAGGCATAAAATTTATCCAATTTATATTATATCAAAAAGTTTATAAAAATAAACATAATAACTCTATTAATATAAATATTTTATCGCCATAAATAGTATATTCAAATACATTACTTTCAGTACTATAAAAATTTAAAAATATATCACTCCTCTTTATTAGTACCCTAAATTTCATTTATTATAAATCTAAGGTAATTATTACATAAATTCAAAAAATATAAGAGAATTTTTATCAAATAATAAGTTTACAAAACTGGACACCAAAAGAGAAGAGATATATTTTATATTGTGTTAAATTTTGAACTAAGGAGGTGATGATATTGAGTGGCTGAAGCAACTAAGCCAAGCAATTGATTACATAGAAAATAATCTAGAAGGTGATATATCTTATGATGAAGCTGCAAAAATTGCTTGCTGTTCAACATATTATATACTGCTTTCGTTTTGCCCGGTATCATATTTCTCGTGATCTTTTCTGTTAGTTGTAGCGGTGGTATCATCAATTTCATTATGAAATCTAGCGGTAGTTTTTATAGAAATCTGATTGCACCTGTGAGACGAAGCTCAATTGTGCTTGGCCAAATGTTAGAAGTGATACTGGTTTCCTTTATGGAAGTAGGTATTTTATTTGTTGTAAGTCTTTTTTCTCAGTAAAGATATCATCCAGCATCACCGGGATTGCTTTTATGATACTACTGATTTTTATGGCATCCTTCTTTCTGTCAGGACTTGCCTATTTCATCAGCCTGTCTTTGCCAAATGAAGTAATATATGAGACAATTATGACTGCTATTATCCTGCCTATATTCTTTTTGAGTACAGCTCTTTTTTCTTCGGGAAATTTGTCTGGAGGTTTGGCTATAGCTGTGAAACTCAATCCATTCACATACATTATTAACGCTCTGCGCAGTTTAATATTAGGAGAAATGATTATGTTTTTGGACATTCTACCCGTCATCCTGTTATTTGCAGTGCTGTGCTGTGGTAGCTTTGCACTGGCAATATGGAGACTCAAAAAAGAAACTTCCCACTAATTAAGATTATAATATTTTTGTAAATACAGAATATAAATCTATAAAAAAGAGAAGATATAAATTTCAAAGATATAAAATTAGCTGCCCTTGTAACTAATAAAAAGTTTTAACTTGATAGATTTCTTTCCTAGGATAAAATTTCATAATAAAAGCCAGAGGATAGTTTGAAATAAAACTCAAATCCGCCCTCTTCTTTTGCTATTAGAGTTACCCTTTATACTAGCCCTTTTTATTTTAAATTTTTATATAATTTTAGTTGTTAAACCTAAATTATATTTTTCATAGCTAGACTGATCCTGTATATACTTAAAACATAATGTTTTTAAATTAATTTTAATATCAGTCTTTTTTATGTGTTTTTTTACTATGCTTAGTCCCAGAATTATTTGCTTTTTTCTTTTTGCTGTTGACTTGCGCAAGATTTATCATTTTTTTCACTCATAGCATTTATCCCTCCTAAAACAAGAATTAAGTTTTAAAACCACAGTACTATTTTCTTCAATATAAAAATTATAATTCTATGAAATAAATAGCAAATAATAATCCACTAGTTAAACTAGTGGTCAGGCTGTTGATAAACATATTTTATCAACAGCCTTTAAATTTATACAAAAAGGATTTCTATTATTTATGTAGAATATATAATATAGGTTAAAAAAATGCCCCGGAGGGCTTTTAGGGAGGATGAAAATGCTTTTTATAGGATACCTATTCGGTATACGTTCTGAGCGTCAGCTAGTAAAAGAAATAGAAGTTAATGTAGCTTATAGATGTTTTTTAGGATTTGGACTTACAGATAAAATTCCTAGTCACTCTACCATAAGCCAAAATAGAACTAAACGATTTAATGATACTAATATATATCAAGAAATCTTTGATAATATTGTATTTCAAGCTATTAATAAAAAGCTAGTAGACGGCAAAATTTTATATACTGATTCTACTCATTTAAAAGCTAACGCTAATAAACATAAATTTATAAAAGAGTCAATTACTAAATCTACAAAAGAATACTTTGATGAATTAGAGAAAGATATTAATGAAGATAGACTAAATTACGGAAAGAAACCTCTAAAAAAAAGAAAAAATAGAAGAAACTAAAGAAATTAAGATTAGTACAACTGACTCTGATAGCAGATATATGATTAGAGATGGAAAACCCAAAGGATTTTTTTACTTAGATCATAGAACTGTTGATGGAAAATATAATATTATTACTAATGTCCATGTAACTCCAGGGAATATAAATGATGTAGATCCATATGTTGAAAGAATAGAAACTCAAATAAAAAAATTTAATTTTAATACAAAGTACATAGTTGCAGATGCTGGTTATTCTACTAATCCTATTTGTAAAAAATATCAGATACACAATACCAAGGGGTTTTTGCTTTTCGTTTAGGTCCTCATGTTAAAGGTAAGTATACTAAATATAGATTTCAATATGTTAAAGAATTAGACGGATATGTTTGTATCAATAACTATTTTTTAAAATATAGAACTACTATAAGAGAACGATATAAAAAATATGTTAGTGATGCGGAGCATTGTGCTCTATGCAAATACAAAAGTAAATGCTTAACATCTGATAAAGCAACTAATAGAACTATACGTAGTCATGTTTGGGAAGACCACAAAGATCAGGTTTTCAAATTTACTAAAACAGATAAAGGCAAAAATTTTTATAAAAGAAGAAAAGAAGCTATTGAGCATAGCTTTGCAGATTCAAAAAATCTACATGGGCTATGCTATGCTCGGTTGCGAGGAATAAAAAAAGTAACTGAACAATGCTTATTAACAGCAGCAGTTCAGAACATGAAGAAGATAGCGAGAGTGCTATCGCACGTTTTTTTCATTCGATTAAAATATTTTTACCTATTATTGCAAGTAATGGGTATGTAGGTAAATTTGTTTTTACATAAATTTACCTGCATACCCATAATTTCGCAAAATGAATGTTTTAACTGATAGGTATTAAATAACTGCTGTATAGTAAACCAAAATAGAATATCTTCTAGATTATACCTTTGTAACCTCTTTTCTATTAATTTCATTTGTCTCTTAATAAGATTGCTACTTTCCATATATACCTCCAGTAAGAAAACAACCTAAACTATTCTAATAGCTTCTCTCTTCTAGAATACACGAATTGTTGATATATAAATCAGGTCTCCTTTTTAAGACCTTGAAACGAATATTAAATGTTGAAATACTTGCAAACTTCGTTATTCATACCTTCCATGTTCAAAATACTTATTAAAAATATAGTAAATTTCCGATTTGGGCTCGTTTTCCCTAATCAGAGCAATCCTAATCTCATCTGTTAGGCCCTCTGCACATGTATACCCTCTTGGAAATCCAACACTCTCTTCAAAATCTTCAATTTCTAATCCTATCTTTCCAATATTTTCAATAGTATAATACTTTTCCGGATCAATTATATGTCCAAAGGTAGTATAATAATCTTTGATAACCTCTAATAGTAACTTAAAGTTTCGCTCACATTGAGTAGCTACATCTTCCTCTAGATCATCTTGCCTATCATTGGAAAATAAGTTCTTCAACAATTTTTCTTGGGGCAGCTTTCCTCTATCATAATAGTTATGGTCACCCATAAAAAAAAATTTACTTTTCATGGCTCCTTCATCATTTTTGTACATACGTCTCGAGCCGATATAAACCACACCTACCTTTTGTGATTCGTTTCTCATTTCAACAAATTTTTTAGCTATTTTTTGCTTGCGCGAATATTCCTGCTTATTAGCATACCAATCAAAAAATCCCTCTATACCATTCATATAAGATTGAAGAGAAAATGTTATACTCCTACATGCTGATACAAATGCACTGAAAAGATACTGACATCCAATCAGATTTATACATTCATTTATTTTTTCAAGAAAGTAATCTGACTCATATATTTTATACTCAACTAAACCAAAAGATCTCATTAAAAAATCACTCCCCGTAAAAATAGTGGCTATCTGTATTTCCGTTTTAAAATTCATACAACGATACGTATTCTACCACTTATTTACTTATTTCACATCATTAATAATACAAGCTGCTCGATAATGATGTTTCATACACCTTTTGAACAGTACTAAAGAAAAACTAACAAAAGTTTGTGTTAGTAACCTGATTAAAACATTGTGCAATAACCATGCCCAAGCTGTTCAATATAATCACAAACTCGATCATAATTAATGATATTTAGGTTATTAACTTCATATATCAACCTATTCTTACGCTCCCTAGCAGAGCTATCCATATACGAGCGTTTACTTACAACTAAGCAATATTGAATTTGAGAAATAGGGATTGACATTCCCTTTTCAGTAAATTCATGTTCATTTAAAAAATAACTGTCGGTTATCATCCATCCAATTTTTCCAATTCTTAATTTGTCCATAGCCTGAGTTAACACTTTTGCTTTCACAATTTCCATCTTGATTGATAAATGGAGTATTTGCATTCTCAAATTCAATGAGTAAAAGATGATATCCATCAGAATTACGACCACATATTACATAATCAACTTTGTACTTGCTGCCCAACATCATTTCAGGGAATAAATAGTTCTCCTTATGTCCAAAGTTATACTCCTTTATTATTGATGCTGGAATGAACCACTTTTTATTAGATTTTATATATGTCTGTATATCATTTTCACTTTTCGAGTTATCAAGTACTTTTTTAAAAGCTTCTGATTCTTTTTTTGATTCTTCGTGGTTTAATTCTCTAGACCAAATAACGTTATTTGGAAACTTAGTTCTATAATGATATACAAAATTTCTAATTTCTTTACTGTACTTATTTATGGGATCAACATGTTCTGGAGAAACTATGCCTATTTTATTAAACTCGTCTTGTTCTCTAATTACCTCCAACTCTTTCGTTGAAGGTTTTTCATAATCTCTTTCATATAAGTTCATAACTTTTCCTCCTAAATCCTTTAATAACTTTTGCGTTAATGATCAGCTTAAATATTAATACAACCATGCTTTATGAACAGGTACACTCTGCCAGCTACACAAAGAATTTCCTTTACTTAAAATGATATTTACACCTAGTATTTGTCTGTTTTCTGTGTTCTTGTAATAATTCTCAACAGAAGCAATGAGGTTATATTGCATTACCAACTTACTCATCTATAAATTTTGGGAACTGTATTCCTTTGAAAACCATAAGCATTAATTCAGCAAGACTTATAGTTAATTGTAAGTTTTATGTATATTGATAATTAAATCCCGAAAACATTAAATATAGTTCCGGGATTTTCTTTATTGCAATTATTAAGAGTCTGCAATCATTATTATAATACCATTCTAGTACTTCTTTAAAATCATCTATGTTAAACCCAAGTTATATGATTTGTTCTGAGAAGCTTACCAGTATAGCTCTCTGTTAATATTAGCCGCAACAAATTGTAAATTAATGCTCCTAAAAAACGGATGCCATTTTACAGGTGCGATAAATCTCATATGTCCGCCACCGTTGTCCCAAACTAGTACAACAGTTCCCGCTAAACCTGCACTAGTGGCTCTAGACTGTAATTCAGAAATAATCTCATTCTGATCCACTTCATTTTTAAACCTAAACGAATCGTTAAGTGGAATAATGATAAGATCAATACCTTGTTCTCTAATATGCGCAACTTCAAACCTTGGCCTAATAATCCACCCATAATATATAATTTGTTTTTCGGCATAAACCTAATTGATAATTTAAAATAGTGTTATAATATACCAATATTATTATATAGTAAATAACTTCCATATTCAACACTTCAACATTTTTTTATTCATAGTATATATCTACTTACACAATTTCACATATCACTACAAATTTTACCTAAATACATGCTTTGGATTCCTTAACATAAACGATATATATTGCAAAATAGTTTGGCTAACTCTATTGAGACGACCTTCTAACCTCTTAATAAAATATTGATTCTATTTAAGGATTCCTATAATAAATAATATTTCTTGACTTCTGCTAATTGCACATAAAAATTAAATCATTTAAAATTACTAAAATTCATCAACATAATATTCCAAAATAGCATAAACATAGTATAATGTATTTATATAACATTATGTGAGGTGGTAAAAATTATAAATGATGAACTAAAATATTCAACTCTATATGATCACTATAAAGAAACAATTTCTTATCTAAAAACAGATTTAACCAAAAGAGATAAGATAACATGGATATTATTAGGCTTATTGGTACTCTATTTTTTAGTTGAATTTAAGCCTATAGATTCTATTAATGTTGCTAATAAACTGATTAAAAGTAAGACTGGCTCCTCAATAATAGTAAATTATGACATCCTAGTTACTGGAATGCTATTACTTATATTATTTTCTACAATGAAATATTTTCAAATGTGTTTATATATAGAGAGACAATATAATTATATATATGATTTGGAGAATAAACTTAATGCTATTTCTGATGAAAAGCTTATAACTAGAGAAGGTTATTCATATTTACAGGAGTATCCTCTTTTATCTGCATTAATACATAGAATATACAATTTGTTTTTACCATTAAGCATAATAATATCTATGTTTATAAAAGTTCACAGACTTTTTAAGAGTCAAATTTCTATTACAATAATTTTTAATATAGCAATTGGAATAGGATGTATATCTATTGTATGTCTATACTTATTATTTGCATATAGACATGTTAAATTTATAAAGTTTATTAACGAATGCGTGAAAAAATTATTTGTCCTATTACATTTATATGAAAAAAATAAGGGGGAACATAATATGGCAAAGAAAAAAGTATGTATTAGTTTTGATTATGAGAATGATAAAAATTATAAAAATTTATTAGCAGCTTGGGATGTAAATACCAATTTTGAATTTTCTTTTAATGACCTAACACCTACAGAAATAAATAGTAACGATTATAGCAGAGTTAAAGCTGTAATCACTCAAAAAATAAGCTCTGCTACTTATTTATTAGTTATTGTAGGAGAACATGCAAATGATGAACATCCTAGAAAAAGTGAAATCGGAGATAGAAACTGGATTAATTGGGAAATTAACAAAGCTAAAGAATTAGGGAAGAAATTAGTTGCTGTAAAAATTAATAAATCTTACGAATCTCCAACTGCACTACTAAATTCAGGAGCTTCTTGGGCAATGAGTTTCACAAAGGATTCAATAATAAAGGCTTTAGATGAAGCCTAAATAATATAATATGGAACAAATAATTAACAAAGGGCTTATTTGAATAAAATAAGCTCTTTTGCTTAAAGAGATAGCCTAAACACTATTGTTTAGGCTACTTATATTAACTATCAATTGGGTTGTCGTTATATTATTTTTAATGTCCAACTTTCACAATTCCAAGTTTCTGTTACTATATCTTCATAAAATTCTTTCTCGTGGCAAACTAAAAGTATAGAACCTTTATATTCTTTTAATGCTCTTTTTAATTCTTCTTTGGCTTCCACATCTAAGTGGTTAGTAGGTTCGTCTAATATTAGTATATTTGTTTCTCTATTTAGTATTTTACAAAGCCTTACCTTTGCTGCTTCTCCACCGGACAGCACTACTATTTTAGATTCTAATTGCTTCGTAGTTAATCCACATTTTGCTAGGGCAGATCTTATTTCGTATTGAGTAAATACAGGGAACTCTTTCCACACTTCTTCTATACAGGTATTATAATTAGATTCTCTTTCTTCTTGCTCAAAATATCCTATGTATTGATAATCACCTAGCGTAACATCCCCTTCCAATGGTTTTATAGCTCCTAATAAACTTTTTAGTAATGTAGTTTTTCCAAGACCATTGGCTCCTACTAAGGCTACCTTTTGTCCTCTTTCCATTTTTATATTTAAAGGTTTTGTTAAGGGTGAATCATATCCTATAACTAAATCTTTAGTTTCAAATATAACTTTTCCAGAAGCTCTAGCCTGTTTAAAATTAAATTCCGGCTTTGGTTTTTCTTTTGTAAGTTCTATTTTATCTATTTTATCTAATTTTTTTTGTCTAGATCTTGCCATACCTACGGTGGAAACTCTTGCTTTATTTTTTGCTATAAAATCTTCTAGTTTTGATATTTCTGCCTGTTGTCTTTCATAGGCTGCCTCTAGTCGTTTCTTGTTTTCCTCATAAATTCTTATAAATTCATTATAATCCCCTACGTAACGAGTAAGCCTTTTATTTTCTACATGATAAATTAAATTTATTACCTCATTTAAAAATGGTATATCATGGGATATTAAAATAAAGGCATTCTCATAGTTTTTAAGATAATTTTTAAGCCAATCTATGTGATCTTCGTCTAAATAGTTTGTGGGCTCATCTAAAAGTAATATATCTGGATTCTCTAAAAGGAGTTTTGCTAGAAGTATTTTTGTCCTTTGTCCTCCAGATAAATCTGATACATCCTTATCCAAACCTATGTCAGCAATACCAAGTCCCCTTGCTATTTCCTCTATTTTAGCATCTATTATGTAAAAATCATTATGATCTAACATATCCTGTATAGTAGCTGTTCTATTTAGCATTTTTTCCATTTCTTCCTGGGATACCTCTCCCATTTTCATGTATAAATCATTCATTTCTTTTTCAAGATTAAATAAATAGTCAAAGGCTTCCCTCAAGACTTCTCTAATGGTTTTTCCTTTTGTAAGATTTAAATGCTGATCCATGTAGCCTATTCTTACATCCTTTGCCCATTGAATTTTACCCTCATCTGGCATTAATTTTCCTGTTATTATATTCATAAATGTAGACTTACCCTCTCCATTAGCTCCAATAAGCCCTACATGCTCTCCCTTTAAAAGTCTAAAGGATACTTCCTCGAAAATAGCTCTGTCTCCAAATCCATGGCTAATATCCTTAACGGTTAATATACTCATATGTAAAAATCCTCCTGAAAATATAATCTAAAATAAACTTTAATTTATAAATAAAGCCTTGTCAATAATTTATTTAAAATATAAATTTAGTTTCTTTTTAAATATATTTTTAAAATTTTATTTGAAGAAGTATTAAAACACAAAAATAAGAGAGCCTAAATATTTAAGATGAGGGGTAAAAAGGGGTAAATAAAGGCTCTCTTATTTTTATATTACAAAACCTACAATAAACTATATAATCTAATATAGGCTTTATATTTTAGGAAATTACTTTAAACTTATAACTGATTATAGTTTCAAACCATACTGATACTGGTTTTATTTGGTGTATATTAATAGGAAAATTTGTGTTTATTTCATGTTATCTAACTCTATATTTAGTATGAAGAAGTTCATGAGCTTTTTCACCATAAGGTTTACCTAAATATTCTTCATAAAGTTTCTTTATATATGGATTTTCGTGAGACTTCCTTATTTCTTTATTACTATCTTCTTTATATAGGGCTTCTGTTCTTTTTTTCAATATATTTGTATCTCCATAGATATAAGGTTGACCACCACCATCTACACAGCCTGATGGACACGCCATGATTTCGATCATATGATATTTAGACTTTCCATTTCTTATATCATTTAAAAGTTTTCTAGCATTACCTAATCCACTAGCTATAGCTACTTTAACCTCTGTATCCTTTATGTTTACTGTAGCTTCTCTTATGCCATCTTCCCCACGAACTTCTATAAATTCTACATCTTTTAAAGTACCTTTAGTAACCCATTCATAGGCAGTTCTTAAAGCCGCTTCCATAACACCGCCGGTAGTTCCAAAAATTACTGAAGCCCCTGTAGATTGACCTAGTGGATTATCAAATTCTTCCTCCTGTAGAGAATTAAAATCTATACCCGCTTCTACTATCATTTTAGCTAATTCTCTTGTACTTATAACAATGTCTACATCAGGAATTCCATTTCTCTTCATTTCTTCTCTTTTTGCCTCATACTTTTTAGCAAGACAAGGCATTACAGATACTACTATAATATCTTTAGGATCTACCTTCATTTTTTCTGCTAAATAACTTTTAGCTATAGCTCCAAACATTTGCTGAGGAGACTTACAACTAGATGGTATATCCATTAAATCATTAAAGTTGTGTTCAAAGAATTTTATCCATCCCGGACAACAACTTGTAAGCATTGGAAGTGTTCCACCATGCTCTAATCTATGAATAAATTCTGAAGCTTCCTCCATAATAGTCAAGTCTGCTGCAAAATCTGTATCAAAAACTTTACTGAATCCTAATTGGCGAAGAGCTGCTACCATTTTTCCTGTAACAGCTGTTCCAGGTTCTAATCCAAATTCTTCACCTAAAGCAGCTCTAATAGCTGGAGCAGTTTGTACAATAACAACTTTATCCTTTTGTGATAGTGCATCCCAAACTTTACTTGTATTATTTACTTCTGTTAAAGCCCCAGTTGGACAGACAGAAACACATTGTCCACAGAAAGTACAATTAGTATTTTTTATAGCTTCAGAAAAGGCTGGTGCTACTACAGTTTCAAAACCTCTTCCAATAGCAGATAGGGTTCCTACAGTTTGAACTTCATTACACATAGTTATGCATCTTCTACAAAGTATACATTTATCCATATCTCTAACTATGGAATAGCTAGAAATATCTATAGGATACATTGAAACATCACCTTGATATTTCATTTCTCTTATACCCATATCTGCAGCTAATTTCTGCAGTTCACATTTTGTATTTTTCTCACAAAGCAAACAGTCTTTTGGATGATCGGATAAAAGTAATTCTACTATAGCTCTTCTAGCTTTTATAGCCCTTATGGAATTAGTTTTTACTATCATTCCTTCCCCTACAGGGGTACAACAGGCTGGCGCTAAGTTTTTTCTCCCCTCTACTTCTACTACACAGACCCTACAGGAACCAGGTTTGTTTTCTGTTCTATTATCATTAAGATGAAAATTACATAGAGTTGGTATATTTATATTTAAAAGTTTTGCTGCATCTAATATAGTAGTTCCCTTCTCTACCTTAAGCTCTTTGCCATTTATATTTAAAGTTACTAAACTCATCTTATTCACCTCTTTCTTCCTATTTCTTTATAATAGCTCCAACTGGACAAGCGCTATAACAATTTCCACATTTAATACATTTTTCTTGATTTATAAAATGTTTTTCTTTAACTTTTCCTATTATACAGGATACTGGGCAACCTCGTGCACATTTAGTACATCCGATACATTTATCAGTAATCTCATAATGAAGTAAATTTTTACAAGTACCTGATGGACATCTTTTTTCATTAACGTGAGCTTCGTATTCATCCATAAAATATCTCATAGTACTTAGTACTGGATTTGGTGCAGTTTGTCCTAATCCACATAAGGAAGTATCCTTTATTATATGTGATAATTCATCTAATTTATTTAGATCTTCTTCTGAACCTTTCCCATTGGTTATCTTTATTAAAGTTTCTAAAAGTCTCTTATTACCAATTCTACATGGGGTACATTTACCACAGGATTCATCCACTGTAAATTCAAGATAAAATTTTGCTATATCTACCATACAATTATCTTCATCCATAACAATCATTCCACCGGAACCCATCATAGATCCTATAGATGTTAATGATTCATAGTCTATAGGAATATCTAAAAGTGAAGCTGGAATACATCCACCTGAAGGTCCTCCTGTTTGAACAGCTTTAAATTTCTTGCCGTTTTTTATACCTCCACCTATATCATATATTATCTCTCTTAGAGTAGTTCCCATAGGAACTTCAACTAATCCAACATTATTTATTTTCCCTGCTAGGGCGAAAACTTTTGTACCATTTGATTTTTCTGTTCCTATGGATTTATACCAATCTGCCCCCTTATTTATTATGGCAGGTATATTTGCTAAAGTTTCTACATTATTTACTACTGTTGGCTTGTTCCAAAGACCAGCTTCTGCTGGGAATGGTGGTTTATAAGTAGGTTCTCCCCTTTCTCCTTCTATGGAGTGTATTAATGCTGTCTCTTCCCCACATACGAAGGCTCCTGCACCATATTTTATTTCTATATTAAAGTTAAAACCGGTGCCTAAAATATTTTCTCCTAAAAGACCATACTCTTTAGCTTGATCCATAGCTATTTTTAATCTATTTACAGCTAAAGGATATTCTGCTCTTATATATATGCGACCTTCGGAAGCTCCTATGGCATAGCCAGCTATAGCCATAGCTTCAATTATGCTATGAGGATCTCCTTCTAATATGGAACGATCCATAAAGGCTCCTGGATCACCTTCATCTGCATTACATATTATATATTTAACATCACTATCATACATTTTTCCAAAACTCCATTTTTTACCTGTAGAGAAGCCACCGCCGCCTCTTCCTCTAAGGCCTGAGTCAGTTATTAATTTTATTAATTCATCCGGTGTCATTTCACTTAAAACTTTTCCTAGGGCTAAGTATCCCTCTGAGCCGATACATTCTTTTATATCTTCTGGATTTATAAGCCCACAATTTCTAAGAGCAATTCTTTTTTGTTTTTTGTAAAAAGACATTTCATCTTGTCTTTTTACTTTTTCTTTAAGTGTTGGTTCTTCATAAAGTAATCTTTCTACTACTTCACCTTTTAATAAATGCTTTTCTGCTATTTCTTTAGCATCTTCTGGTGTTACTTTAACATAAAAAACATTATCTGGATTTATTTTAACTATAGGACCTTTTTCACAGAAACCAAAGCATCCTGTAATAGAAACTTTTACTTCTTCTTGGAGTCCTAATTTATTTATTTCTTCTTTTAAACTTTCTACAATTTTATCACTGTCAGCTGATTTACATCCTGTACCGCCACAAACTAATATAAGTCTTTCACATTTTTTATTTTCTACTGCTGTTTCTTCTTCATGGGTGGTATGTCTACTTTTTAATAAATCCTTATAGTTTTCATAATAGCTTTTCAATTCTTTATAAGAATTAATTTTCTCCATAAATATCCCTCCTATGCCCCATATTCTTCCAATACTTTATTTACTTCATTTTTAGTAAAATGTCCATATACCTTATCATTAATTGTAACCACTGGAGCTAATCCACAGGCCCCTACACATCTCAAAACTTGTAATGTGAATTTACCATCTTTAGTGGTTTCTCCAACTTTTATATTTAATTTCTTTTCAAATTCTGAAAGTACATCCCCAGCTCCCTTTACAAAACAAGCTGTGCCCATACAGACATTTATAACATTTTCACCCTTTGGTTCTGTAGTAAAATAAGAGTAAAAAGTAATAACTCCGTAAACCTTTGAAACAGGAATGTCTAGCTTTTTAGCTACAAATTCCTGCACTTCATTTGGAAGATATCCAAAAATATGTTGAGCCTTATGAAGTACTTCTATAAGGGATCCTTTCTTATTGGAGATATTGTTTATATATTCTTCTAGTTCTTTGAATTTGATATTTACTAACTCATTGGAACACATAGGAATCCTCCCCCTTTTTGCTATTTGAAAAATCCATTTATTTTTTTATTTTATATTATACTATAGATTCTTTAGAAAATTAACATATTTCTGAAAATTAATTGTGGTAAATTTTACTTTTATCAATTTCATTAAGTTTTCGTTAATTTCAGGGAGATTTTTTTACTATTATTTAACAATCTTTTGCTCAAATCCTTCATTCTTATGTATGATGAATGATAATAAATTAACATAAATTTTGTATAAAAAGGTGTTTCAAAATAAAATAGATTTAATTTTAACACTGCAAAGATAAAAAATACACTTATAAATCAATTAATTTCGCTAGATTAAGAACTATTAGAACTTATTCATATATTTAGTATTTGTATTTTTTAATTTGTTATATTAAAATTAAATCTATTTTTATACAACTTAGTGATTTTCTTGCATTTTTCAAAATTTTTTATAGCAAAAGAAATATATTTTATAAAAAATTTGATCTAGTCTAAGAAAGGTTTGATTCTAATAATCTTGGACCAGATAAATTTATTGCTATAGCTCCCAATGGAGCTGTAGTTAAAATCGACAAAACTGCTATTGCTAAAATAATATCTCCTGCCGCTACACCATTGGCTAATGGTACTGCGCCCATAGCTGCTTGAACTGTAGCTTTAGGGATATAGGCTATAATACAAAAGAGTTTTTCTTCTTTATTTAAATTTGAACCTTTCAGAGAAATTAATACTCCTATACTTCTTCCTATAAGACCTAAAGCAATAATGATTATACCTAAAAATCCTGATTTAAAAGCTATTACCATATTTACTTCAGCTCCTACGAGAACAAATAAAAGTATTTGAGCAAAAACCCATATTTCATTTAATCCTTTAGATACCTTATCTCCTATACTAGGAATTTTATCAGATATTACAAATCCTAAAGCCATAACACCCAATAAGCTAGCTATTTCTAATTTACCTTTTAGTAAAGCTTCTATTAAAGTAAGTATAATAGATATACTAAGTATAATTAATATCTTTTTAGTGTTATCTATAGGATACTTTTTAAATATCTTTATAATAATGATTGCTGATAATACACCAATTAATGTACCTAATATTATAGAAACAGGTATTTTTAATATCTGTATAGCTATATTTATATTCTTCCCCGCATATAATCCTAAAAATGTGCTAAATATTGTTATTGCAAAAACATCATCTATAGAAGCACCGGCTAGTATAAGAGTTGGTATACCCTTAGCTTTCCCAAGACCTTTGTCTATTAAGTTTAACATTTGAGGTACAACTACTGCTGGTGAAACTGCAGCAATAATAAATCCTAATAAGCCTCCTTGTACAAAAGAAAAACCTAAAAGTTTTACGGAGGCTATTGCTATGAATAATCCTTCTATAATTCCAGGTATACAGCTTAATTTTAGAGCTGTTTTACCAACCAATTTTAATTCTTCTTTATTAAGACCTAATCCTGCCCTTAATAAAATTACAATTAAAGCAATTTTTCTAAGATCCGATGAAGCATTTAAAATATCTTTGCTTAACCAGTCTAAGCCATGAGGTCCTATTAAAATACCTAATATTAACATTCCTAAAAGACCTGGCAGTTTTAATTTTTCAAAGAGCTTATTTGCGATTAATCCCAATAGAATAATAATAGCTAAACTTGATGCCATAAAATTTCCTCCTTTAAATTTTACTCAAAACGCAAAAAATCCTACAAATAATTATATTATTTGTAGGAGTCATTAGCATTACGCAATTATGGCGAACTCCATCGCCTATATTTAAAATACTTATTTAATTTACCATAATTTATTATTATAGTCAACAATAAATTTTATTCAATTAGTAATTGTTATATTTTCCACAGATCACTGTTTATTTATTTAACAATTATGTTAACAAATTATTTACTTTTATTAATAAAAATTCTAACCATTTTCACTTAGTTTTAAGGCTATATCTAATAATTCTTGTTTTTTATCTATTATGTCTGTCCATCTTTTTGGTAAGGCATTATATCCATAATATACACCAGCTAGTCCTCCAGTTATTGCTCCTATACTCCCAGCATCTCCACCTAAATTAACGGCTTCACATATAGCTTCTTCTGCTGTAGTTGTATTCATAATACTCCAAATAGCACACATTAATGAATCTACTGCAAAAAGTGATGAATTTAGTGAGTATTTATTTATATTTGTTATTTCATAAAATTCATCAAATTCTTTAAGTGCTAACTTTAATGCTTCATTTTTGTCATAACCTTTTATATAATAATAGATTAATGTATTATACAAAAGGCAAGCTCTCTCCCCAATTTTACTTCTATGAGTTAATTGAGACTGTTCTTTTGTTATTTTAATTATTTCATCATAATCTTTATAATATAAAGCTACAGGCAGACTTCTTTTTAAGGCTCCATTGCCAGCAGCTTGCCAGCTAAGTACTTCACTGCTGTGTAAACTAGCTTCATACCAGTCTCTACATTCTAAAAATTTTTCTATAGTACACTTTACAGTTGTGCCTCCATATTTCATTAAATCCTGATATACTTTCATAAATTCATTTCCTATACTATCTTGTGGATCTTCTGGGTTATTTAATATTCCTTTGGCTACACATAATACCATTAAAGTATCATCTGTTGTACATCCTGGCTTTAGATCAAAAACCCCACCACCAACTATTTCTTTTAAATATCCATAGTTATGAATTTCTTCTTTATCCATATTTTCTAATGTTATACCTAAAGCATCTCCACAGGCTACTCCAAATAAACCTCCTAATATTCTAGTTTTTGTATCCATATTAATGCCCTCCATACTAAAAAATAAATTTATTTGTTTTTTATTATATCACATAACTATATCATAAATAGTACTAGCTAGACAAAATTCAGAATATTTAAAAATTTGTTAATATGTGCTCATGCTTTAATTGTCTTTACAATGTATTTATATAATATTATATAGGTTGTAAAATCTATTACAATATAGTAAAATTTATAAAGCACAAGGCTATTATTATCTATAATTGGAGGTTAAAAAGGTGACAAAAAATAAAAAAATACCATTCTTAGAGTTTATACCTATAATAGTGATATCCTTTCTACTTTTAAAATTTATAAACAACATAGAAAATATTTATTCTTTTATAAAATCTTTTTTATCAATATTAGTACCATTTATTTGGGCTTTTGGAATTGCTTATATGTTAAATCCATTAATGAAATATTTTCAAAATAAATTCAAATTGAATAGGATATTGAGTATTATTTTAACTTATATAATTGTAATTGGGCTTTTAACACTATTTATAAATACTTTTGTTCCTAAGATTATAAAAAATGTTGGAGATTTATTTGCTCACAGCCCTGATTATATTAATAAAACAATTCAGTGGTTTAATGAGAATATAAAATATTCTAAAGCATATGATATGTTAATGGAAAATTCTCAAATAAGTAATAATATACCTAATTTAATAAATAAAATATCTAATTTAACTAATACATTCATAAATACATTTTTAAATACTACAATCAAATTTACTTCATCTTTAGTTAAATTTGTATTTGGATTAATCATTTCTATATATCTTTTATTAGATAAAGAAAGTCTTATAGAAAACTTTAAGAAATTTATATTAGCACTAACTGGTGAAAAAATTTATTCAAAAACTTTAAGTTTTTTTAAAGAAGTTGATCTAGTTTTTTCAAAGTTCATAATAGGTAAAGCTATAGATTCTTTAATAATTGGTTTGATGTGCTTTGCAGGATTAAATATAATGAAAGTTCCTTATGCTGCTTTAATAGCTTTTATTGTAGGAATAACAAACATGATTCCTTATTTTGGACCTTTTATAGGAATGATACCTGCTTTTGTAATAACCTTATTTTTTAATTATATAAAAGCTATTTGGGTTTTAATTTTTATAATAATACTTCAACAATTTGATGGTTGGTATTTAGGTCCTAAGATTCTTGGCAATCAGGTTGGATTAAGTCCTATATGGATAATATTTGCAATAACTATTGGTGGAGGAACTTTTGGTGTAATGGGTATGTTTTTATCTGTACCTATTGCAGCCATCATAAAAATTTATTTAGATAAATACATAGAAATGAAATTAAATAAAAAATAAAATAGATTAAAACAACAATAAAGGGATATCTCAAAATTAAATAAGTATTAATTTTAAAACTCGAAATATAAAATTAAATCTATTTTTAATTAGATATCCCTCTTATTAATGCTTATTTATCAGAGATACATTTTTTCTTATTTAAAAACCAATTTTTTATGCCACCCTTAGATAAGTTATTTCCTGCTTTAAGTTTTTTAGTATAAATTAGTTCATTCCCATTTAATATAGAAAGAGATCCAAAATCTTCACCTTTTTTTACTTTCCAATTTAACTCTTTAGGCTTATTTATTTTTATAGAATAATCCGCTCCATTTTTAAAAGGAATAATTATATCCTTATCTGCTATTATATTTACGGAACCTTCCTCAAAAACAGCCTGATCTAAAATATCTCCTTTAGTACATATTTTTTTGAAGTCATAATTATTTTTAACATAATTATGTATCTTTGTTGTTTCGTTCCATCTAGGAGTGCAATTTAAAACAACTATTATAATATCATTACCATTAATTTTAGAGGAGGTTACTAAACATTTACCTGCTTTCCCAGTATATCCTGTTTTAACTCCATCCGCTTCTGGTATTTTCCAAAGTATTTTATTTATATTGTGGTAATCTCTTGTAAAATTATATTCTTCTTTTTTTACATCTTTGGAGGATACTATTTTATTAAACAATTCATATTTCTTAGCAGTTGCTGTAGCTAGAGCTAAATCATAGGCTGTAGAGTAATGTTCATCTTTATCTAAACCATGGGGAGTTATAAAGTGAGAATTTAAAAGTCCTATTTCACTAGCATACTCATTCATAAGTTTAGAAAAATCTTCTACACTTCCTGCTATACCCTCAGCTATAGCTATAGCTGCATCATTGCCGGATCTTAACATAAGGCCATAAAGTAATTCTCTTAAGGTTATTTTTTCCCCTTTTCTATACCCTACCACAGATCCTCTTATTTTATCTGCATTTTCAGAGATTTCTATTTTTCTATCCAAGTCTCCATACTTTAGTGCTACTAGAGTGGTCATTATTTTTGTGGTACTTGCAATAGGAACTATTTCGTTGGCTGATTTTTCAAATAATACTATTCCTGTATCCTTATCTATAGCAATAGCACATCTAGCATTAATATAAGGTGGTTTGTTTTTTTGAGATTCTTCTTTTCCGTAGACTTTTGTTGGTATTAATGTAACTATAAATATTAAAGAAATTATTAATATAAATTTGTTTTTTAGAGTTTTTTTCATCTTGTTCACTCTCCATTTATGTTGTATTTATTATTTCTAGAGTTTTTTAAGAGTAAATAATTTTTTAGTTTACTTTTTAGTTTAATTTACATAATTTTTTATATGTTTACTTATATGATTGGTTATATTTTTTTTATTATTGGCAATAATTTATAATATTTAAATTTCTAGGAGGCTTTTAACATGCTTTTTTTTATTATTTCAATATTTATAATTTTTATACTTATTTTAATTATGCCTTTTAAAATAACAGTTATATATTCCGATAAAGACTTTAATATATATATATATAATTTCCAGTGGAAAAAAGGGGAAGATATAAAAAAGCAAAATTATATTAATAAAAAAATAAATGTGAAAAAAGATAAGAAGAAGCAGAAAGCTTTAAAAGTAACTTTAGAAAAATGTAGCTTTAAACCTAAAGCCAATATATCTACTTTTTTAAATTACGACTTAGAAGATGCAGCCTATTCAGCTATTATTTATGGGGTACTGCAAAGTTTAGTACCTTACATTTATAGATATTTATTTAAAATATTTAAACTTAAAAATTTCAATTATAATATAACTCCATTATTTAAAAATAAAAATTTTATAGAGTTTAAATTTAAAGGTATATTTTATATAAGCTTGGTAAAAATTATATATATATACATTTCATTTAAAATAAATTATAAAAATTTAAAAAGAGCATAAAATAAATTTATTAATGAAATTTTTAATATAAAAAATCTATTAATAAATTATATAAGGAGGTTTTTTAATGGATGGTCATCCTATTGAAAATTTAATGAAAAATACCATGGAAAACATAAAAGATATGATAGATGTAAATACAATTGTAGGTGATGCTTTAAATAGTCCTGATGGTACTACAATTGTACCTATATCTAAGGTTTCCTTTGGTTTTGCTTCTGGTGGTTCCGAGTATTTATCTAGAAAAAACAAAATGAAAATGATTTAAATTATCCTTTTGGTGGTGGTTCTGGAGCGGGTGTTACTGTAAAACCAGTAGCTTTTTTAGTAATAAAAGGTGATCAGATAAGACTTTTATCTGTAGATCATAAAAATACTTATGAAAAATTAATAGATAATGTACCTCAAATAATGGATATGTTAAAAGATAAGTTTGGTTATAATAAAAAAGAAGATGATTATGAGAAAGATTCTAGCTGCGATTGTAATTTTAACAATCATGAAATCTAAATAAAAGCCCCTATTACATACTTAGGGGCTTTTACACTATTTTTTAGTTCATCCTAAGAATTAATTTTCTTCTTTACTAAATTCTTTTGTAAATCTTCTAAATTAGGAATTGCTTCTATGCTATCTAACCAAAAAATTTTAAAAATTCTTCTGTAGTACCATATAAAATAGGTTTACCTGGTACATCTAGTCTACCACATTCTTTTATAATATTTTTTTCTAGCAGTGTATATATAGCTCTATCGCTTTTCACTCCCCTTATCTCGTCTATTGCCACTCTAGTTATAGGTTGCTTATATGCTATGATTGATAATGTTTCTAAAGCTGCCTGGGATAAAGATTGTCTTACATTAGTTTTTAATAGTTTTTCTACATATATGCTATTTTCCGGTTTAGTTACTAGTTGAACAGCTCTATTATGTATTAATATTTTTATACCTCGATCCTTACCAACATAACTATTGTTCATTTCATTAAGTAATGAGCTTACTTTATCCTGTTTACAATTTAGTATAGTTGCTAAATCTTTTATATTAATAGGTTCTCCACTCATAAATAGAAGGGATTCTATTATAGATTTATATTTATTCTTTTGTGATACTTCGTTTATTTCTAATTGCTCTTCGTGATCTTTATTCACATACAACGCCTCTTTCTATATATATATCATTAAAATTATTAGATTGATATACTTGTATTGTCTTTAACTTTATAAGCTCTAGTATAGCTAAAAAAGTTACCACTATTTCCATTTTGCAACTACATTCTTTTATAAAATCAGAAAAAAGCCATTTTTCTTTTGAGGTTATTTTTTTACCAATATATTTTATCTTATCTTCTATTTTATATTTATCTAATTGTATTTCTCCTTTAAATTCCACATTTTCATTCATTTTATTTGAATATTTACTTATTAAATCATTATATGTATTATATAAACTTAACATTGTTACATCTTTAAGTAATTCGTCTGTGGTTGTTTCTTTATTTTTAACTTCTATAATTTCTGGTTTTTTACTAAATGATGTTCCACTTATCTGCTGACGGTTTTTAAAAAACTCTGCAGCAGCTTTAAATTTTTTGTATTCTAAAAGTTTGCTTAAAAGTTCTTTTTGAGGATCATTCTCCTCTTCCTCTTTTTCTTCTTCTACTTTAGGTAATAAATATTTAGATTTTATTTCAATCAAGGTAGCTGCCATAACTATAAATTCTGAAGTTATTTCTAAGTCTAACTCTTCCATTTGATTTAGGTATTGTAAATACTGATTAGTTATTTCATATATACTTACATCATATATTTCCATTTTATTCTTTTTAATTAAGTGTAGTAATAAGTCAAAAGGTCCATCGAAATTATGTATTTTTATATTTAATGGCATTTTTTATCTCTCCCGTATTATCTATTAAAAAATTTTCTTCATCTAATAATCCTAAATTAATTTTATATTTTTTCATATATTCTAATATTAATCCTATTTCTTTTCCTTCTTTTATACCTAATTTCTTTATATCCTGTCCATTCATAGCTAAATTCATTACTCTTATATTTTTTTCATAATTGTATACTTTATATCTAAACTTTAGATTCCAAGCTAATAAAACTCTTTCAACGCTATAAGTTTTACTTAATATTTTATAAATTTCATAGTTATCCTTGGCATTAGATAAACTTAAACTATAAATTTCTTTATTCTGTAAATATTTATCTATAGGCTTTCTCAAATCTTTATCTAGGAAGGAATTATCTATAAAAATACTTTGTCCATGTTCACCTTTTATTGAATAAAGTACATTTAATATTCTAACATAAATATTAGAATAATCTAATAAAATATTTTCTAATCCTAATAAGTTTAGATTTATATCTAATAAATTATATTTATAACATTGCTTTATAGCTTCTCTCCAATTCTCTTCGGTACATAGGCTATATAGTTCACTCACTATTCTATCATTGCTAATATTCTTTAAGGTGCCTTTTGTTATACTTTCTCTTATTTCCTTTTCATCTTCTATTTTAAAACTATACCTTTGAAGCTTTTTTTATTTCATTTATTACTTCTAATTCTTTTTCTGTAAATTTATTTAATATATTCATACTTAAATAAAGCTAACATGAAATAATCATGTTAGCTTTTATCCTCCTTATGAATCATATATATTCTTATTATATACCCTTATCTATTAACCTTTCAAATCCACCTTTAAAGTGATTAAAAATTCCTGATTTTCTTATATTTCTATCAGAAGTTATTTTAACTTTACCTATTAAATTACCATCTGAATAAAACTCACATATACCAACTTCTTCGTTTATTTTATACTCTTTCTTATTTTCATCTATAATACATTTATTAGTTATTTTTGTTTTCTTACCTTTTTCTATTATAGCATCTAATTCTTCACAGGATTTTGCCATAAAGTATTTATCTCCTTTAGAATTTAAAGGTACCTTTGATATTACATCTCCTTTTTTAACTAAAGTTTTGCATTCAAATTTTGAAAATCCGTAATTCATAAGTTTACTAGCATCTTTATTTCTTATTTTATAAGTTGGAGCTCCCATTATTACCGCTAACATTCTTACTCCATCTTTTTTCGCTGTGGCTGATATACAATATTTAGCTTCATCTGTAAATCCTGTTTTTAGCCCATCACAGCCTTTAAAGAATCTAACAAGTTTATTATGATTTACTAATCCTATAGGGCTTTTCCTTCCTTCTGATATGGTTTCCATATATGTTCCTGTATATTTTAATATTTGTTTATGTTTTAATAGTTCTCTTGACATTATAGATATATCATAGGCTGTAAGTTTTGTGACCTTCTACACTAAGCCCAGTACAATTCTTAAAAGACGTATCTTTCATATTTAATTTTTGTGCTCTATCATTCATCATTTTTACGAAAGCTTCTTCGCTTCCTGCTAAGTATTCTCCCATAGCTACTGCAGCATCATTCCCAGAAGCTATTGCTATACCTTTTAAAAGGTCTTCAACAGTTCTTTCTTCTCCTACATCTAAAAGCATGGTGCTTCCGCCCATTTTTTTAGCGTTTTCACTTATAGTAACTTTATCAGTTAACTTTATTTTCCCACTATCTACTGCTTCCATTGATAGAAGCATTGTCATAATTTTTGTAACTGATGCTGGAGCAAATTTTTCATGAGGATTTTTTTCATAAATAACCTTTCCTGTTGTAGGTTCAATAAGAAGTGCTGATTTAGCATCTACATCTAAGCCACCTTCTTTATTAGAATCTTTATCTTCCGCTTTTTCTTCTCTTTTTAACTGATTTTGTTGGTCATATGCGCTTACTGGTGTTACAAATACACCGAAAATAAAAGTTATGGTAATTATTACACTGAAAAAGTAATAAATTTTTCTTTTCATATATAGTTCCCTCCTTTACAAATATTTTCTCCTGAATTTCATAATATTATCACGGAAAAATTTTCTATGGAAAAAATTAAATTTTATTAGAAGGAATAGCAAGACTAATCTTATTATATAGATTAATTTAAAGAAAAATATCTCATTCTAAAACAATTAATAGCTACATAAGCTAATTTATTCATCAATTTATAATTTGCATAAGCACCTATTGGAGCACCTATACCGGGAATAATTTGGAGCATCTTTGAAAAATCTATGTAATCTCTATATTCTTGCTGAAACTCTCTCCAATTAAAATCATTAATATTATCCGGTAATTTTTCGCTATAACTACTCCAATTTATAATTTTATTATAGGTTTTCTCTCTCATATCCCTCTAGAAAAGCTAATTGGAAATATATAGAATATATAATCTTTCTTTATATTCCTTAGCATCAATACCATATATACTAGCTAAATTAAATAAAAAATTAATTTTAATTGTTAATAATATGGGAAAATCTGCAAGACCTAACATTAGACCACCTAATCCTGTACCTGCTCCACTGATTGTTGCTGTTTTCCTATATAAATTTAACTTTTCATAAGCTAAATTTTCCCTTTCTTCTAAGTTGGCTAATTTAGGAGGTTTCACAGTAACATATTTAGAGGTGAAAAGTACAACCTTTATCATATTTTTAACTCCTTCAGTAACTACCATATGTACTTTTTCAGGAATAAAGCTATTGGTTTTATTCTGAACTTTTTTTGTAATTTTATAAACTATAGAATCTCTTTTAGTCATTTCTTTTTTAAATATATTTAACTCATTTATAGCATCTATTTCATATTTAGTCATTGAAAATTCTCCTTACTTTTATTTTCACAATTTATTTTTACATAATCATTACTAGATTTAATATTTCACTTTAAGCTAAAATTTCTTTTTATATATTACCTAACGTGTTAGGACCATTAACCTATTTTATATTTAAATATGTTAATGGTCCTTAAGAATTATTTTAATTTAAATTCCATCTTAACAGGATTATGATCTGTATTTTTAAATTCCATTGGATAAGCTTTTACACTTGTAGCTTCTATATTATCTGATACTAAAAATCCATCTATAACAGCTGTAAAATTTTCTCCTTTTTTATAAGGTGTAGCATCTGTTCGAGTGGTTGGAACATTTTTATCTGCTACCCACTTAAATCCCTCTGGTTTAAAATCGTTAGGTATTTTTTGAAGCCAATCTGGCCACTTTTCTGTAGTTTTAAACATTAAAGGATCCGTTCCCGGTATTAAGTGATTCCAATCTCCACCTACTATAATATAATTCCCTTTTTTATATTCTTTTATTATATAATTTTTTAAAAAAGAAAGTTGTTGCTTTCTTATTTTGCCACCTTTATCATAAGCAGATAGATGAGAATTTATAAGAACTAATTCCCTATCATTTTCTAGAGATACTCTAGATTCTAAAAAACATCTATCTAATTCTGCTAATTGTCTTGGCCAACTTTCTTTACCTGGATATTGATATCTAGTGGCTGAATTAATTTTATACTTAGATAAATTTACTAATCCTGCATTAACAGTCCCATGTGGTTTCAATATAGGTACTGGTACCCAAGGCGTTTTATAATTTAATGCCATACTTGAAGAATATGCTTTCAAGCTATTTTTTAAGTAATCATATTGATCTATTCTAAAACTTCTAGTTGAATTAGTGTCTACCTCTTGTAAAAATATAAAAGAGCTGTTATCTTTCTTCAAAAAACTTGTAATTCCCCTCATATTTTCCATGGTTTTTTCTTTGCTAGATGATCTGGAACCTTTACCTCCATCCATAAAAAAATCTTGTTTATCATCCATACCACCATAGCCTATATTAAAAGTAACTATGGAAAAACTGTCCTTTAAGTTTAATCTATCCTCTGTTTGTCCCTCAATAGATAACTGAATCTTATCCTCTGGTTTATAATCCGTTACTGTCATAAATAAGATATATCCTGCTATAATTAATATAACTAAAATAATTATGCCCAATAAAACTTGCCCGATTTTTTTCAACTTTAAGCACCATCCTCTTTCCCTTTATATATTCTAAGTATATTTTAATTGGATAAAATTATCAATAAAAAACACAATAAACCTAAAGCTTATTGTGTAAATTTATATTTATAACTATTAATTTATAAAATATGTTCTGTACTAGATTTCTAATAATTTTACAGATACCCCATCTAAAGAAGTTAAATCTTTACTTAGATTCTCTATATCTTCTTTCTTATTATTTAAAAGTTCTAATAAAATTAAACCACACTTTGAACAACTATCATTAGTAGCTTCATGAAGTCCTAATCTTGTTTTTATTATGCAACCATTTCTAGTTAAAATCTCTTGAACATTCGGGGCAATCTCATTTCTAGGAGAAATTTTTATTGCCATAATTGAAAACATATTTGTTCCTCCTCTATGTTTATATGATTATAACTTTTTATAATTATAGCTTTAATTTAAACCTACTTTAAAAATTAAATATGCTTTTATGAATGCTTTAACTATGCTATTTTACTGTATCATATATTAAAGGTAATTCTTCTTTTAACTCTTCTTCTATAACATAATTATTTAATATATCTTTTTCAGCCTTTTCTCCTTTTATTTTATCATTAGCATGAATATAAGCTATTATATCTCCTTTTTTAACTTTATCTGATCTCTTCTTGTTTAAAACTATACCTACTGCTAAATCTATAATGCTATCCTTTGTAACCCTTCCTGCTCCTAACTCTGATGCTATTATCCCTATATTTTGAGCATGAATTTTATTTATATATCCATTTCTATCACAAATTACAGGAATTATATATTCTGCCTTAGGTAATTTTTCTGTATTGTCTACTAAAGTACCATCTCCGCCTTGAGATCTAATAAATTCTTTTAATTTTTCTATAGCTAATCCTTTTTCTATAGTACTTAAAAGCATCTTTCTTGCTTCCTCTATAGTATTTGCTTTTTGTGATAAAATAACCATATTACTTCCTAAGGTTAAACATAATTCTAATAAATCCTTAGGACCTTTACCTTTTAGTGTATCTATAGCTTCTTTTACTTCTAAAGCATTTCCTATAGCATAACCTAAAGGTTGATCCATATCTGATAATATAGCCACAGTATCTCTACCTACACTTTTACCTATATTAACCATTTCTTCCGCTAACTCTTTTGCAGTTTCCGGAGTTTTCATGAAGGCTCCTTCTCCAACCTTTACATCTAAAATTATGGCATTAGCTCCTGCAGCTATTTTTTTGCTCATTATACTAGAAGCTATTAAAGAAATATTGTCTACTGTAGCAGTAACATCTCTTAATGCATATAATTTTTTATCCGCTGGAGCTAAATCTGCTGTTTGAGCTCCTACAGCTATTTTAATATTGTTAACGTTATTTATAAATTTATCCTCTGTCATATTTACTGAAAAACCTTTAAAAGATTCTAATTTATCTATAGTTCCACCAGTATGACCTAAACCTCTACCAGACATTTTAGCTACAGGTATACCTAAGGCTGCTACCATAGGCGCCAAAACTAAGGTAGTAGTATCCCCAACTCCACCAGTACTATGTTTATCAACTTTTATACCCTGTATTTTTGATAAATCCAATATATCTCCAGAGTTAACCATAGCCATAGTCAAATCTACAGTTTCTCTTCTTTTCATTTTTTGAAAGTATATAGCCATTAAAAGAGCTGAAGCTTGATAATCTGGGACATTACCATTAGTATATTCTAAAATAAAATAATCTATTTCTTCTTTGCTTAACTCTCCGCCATTTCTTTTCTTTAGGATCAAATCATACATTCTCATAATTTATTCCTCCCTACAAAGCAATTATTATATAATATAAGGATTGCCTCCAAATAGATTTAGTTTTAATGTATACACATTTATGACTTGTTAGCGAAATAAATTAGTTTATAAAATGCATAGTATTAAAATTAAACCTATTTTATTTTGAAACACTCATTCAATCTTTTTACACTTTAAATATATTAAGTGATTCTTAGGAGCAAGTAGAGCTTGTTTATACAAAACATTTCTATGTTTGACCCTAAGAATCACTTATCAACCCATTTTTTATTATTAAAAATTTTACATAACTTCTAATATTGATTTTAGTAAGGATATGAATTTAGATCTTACTTTATTAGATGTTTCTATAACTTCTTGATGGTTTAGTGGCTGCTCTAATATACCTGCTGCCATATTGGTTATACAAGATATTCCCAATACTTTAATTCCACAATGATTTGCTGCTATAACCTCTGGTACTGTAGACATTCCTACTGCATCTGCCCCTAACATTCTTAGCATTTTTATTTCTGCTGGTGTTTCATATGAAGGTCCTGTCATCATAGCATATACTCCCTTTTGAAGAGAAAAGCCTAATTTTTCAGCTTCTTTTTCTGCAAGGACTATCAAACTTTTATTATATGCTTCTGACATATCTGGAAATCTTGGTCCAATTTCCTCATCATTACTACCTATTAAAGGATTACTAAAAGCAAAATTAATATGATCTTTTATAATCATAAGATCTCCAGGATTATAAATTTCATTTACTCCCCCAGCTGCATTTGTAACAATTATATTTTTTACTCCTAGCTCTTTCATTATGTATACAGGAAGTACTACATCGCTCATTTTATTTCCTTCATAATAATGCACTCTCCCTTGCATCATTATAACCTTTTTGCCCTTTAAAGTTCCCACTACAAACTGACCCTTATGTCCTTTTATAGTTGAAGCTGGCATATTAGGTATATTGGAATATTTTATAATTTCTTTATTTTCTATTTCCTCAGCTAAATCACCTAAGCCTGAGCCTAAAATAACTCCAATTTCAGGCATTATAGATATGTTATTTTTCACAAAATCTGCACTTTCTTTTATTTTCTTTAAATTCAAAATTAACTCCTCCTTTATCTTGAAAGCTTTATTAAAATTATGCCCTTGGATGAGCATTTTTATATACTTCTGCTATTTTACTCTTCTTTGATATACTAGAATAAATTTGAGTTGCAGCTAGATCCTTATGACCTAAAAGTTCCTGTACAGATTTTATATCTGCTCCATTTTGAAGTAAATGTACTGCAAAGGAATGTCTTAGTGTATAAGAATCTATTTCTTTATCTATAGATGCTTCTTTTGCATAAAATTTTATTATTTTCCAAAAACCTTGCCTAGTCATTTGAGTTCCCTTTAAATTTAAAAACAAATAATCTAAATTATATACATTTATAGCTGGTCTTACTTCTAAATAATTCTTTAAACACTTTATCGCATAGGAGCCTATAGGTATAATTCTCTCTCTTTTTTTACTGCCTCTACATTTTATATAATTAAACTTCAAATTTATATCATATATATTTAGATTTAAAAGTTCTGTAATCTTAACTCCCGTAGCATACATAAGTTCTAGCATTGCTTTATCTCTTAATCCCTTTTTTGAAGAATTTGGGGAATTTAAAAGTTTATCCACTTCTTCTACAGAAAGTATTTTAGGGATAGTTCTCTCTATTTTAGGTATTTCATATCCTAGTGTAGGGTCCTCAGATACCATGTTTTTTTTAATTAAATATTTATAAAAATTTCTTATAGATACTATATTTCTTACTATTGAAGAGGTAGCTCGTCCTTCTCTTTGCAAATATTGAACGAAAGCCATTATAGTAACTGTATCAACAGAAAGTATTTTTTCCTCTCTGTTTCTAACAAACTCACTAAACTTCTCCACATCTCTTCTATAAGCCTCTAAAGTATTTTTACTTAAGTTTTTCTTTTGTAAATCTTTTATATAATTCTCTATAATATTTTTCATTTACCATTCCCCTATTTTTTAAGCTTACTTTATTATATTCAACAAATTAATTTAAAAACCTCTTAAAAAATTATTAAAAACCAGTATATAATTATATATAATTTTTATTTTTAAATCTATATTTTTAAATACTAAAGTGCTATTTTCATATACCTTATTTTTCATAAAAAAATTATAAAGAACTGAATCCAAGGCTCTAGGCAATAGGGATCCAAAAAACAATAATATTAAAAAACACTTTATTAAAGTAACTATGGCTTTTTTATATTCTATAAACATAGCATACAAACCCCTGCTCTTGCTACTACTAGTTTTATCATATTGGGTGTTATATAAGATTCCATTAAAAATCCTATAAACATAATTACTACTACAAATGCAAAAGAAAAAGAATAGGAGGTAGCTCTTACCCATATTCCATTTTGAAATCCCCTATTATTTTTATCCCTTAGTATTTGTATTGAAAATTCCATTGATAGCACTGATGCAAATATTATACAAGGAATATATATTAAATTTTGAGGTAATACGCCTAAAAGGGACATCCATATCCCCTTCATTCCCAATCCATTTACAATAAAGCTTGTGGTAAAACCTATTGTGAATCCTTTTATTACATCTATTATGAGAATAACTGGAATTCCTATCATAGTTAATCCTAAAAACCAAATAGCTACAATAATAGTTATATTATTTTTTATAGCTTCAAATAAAATTGATTTAGAATCTATTCCATTAGATGAAATGCTTTTACTAAAACTCTCTACATAGCTTAAAAGATCACCTTTCTCAAAAGAACCCATATATTTTACTGAGTATATACCTAATACTATACCAGTACAAATACATAAAAGACTTATAATATATAGCCAAAAATTTTCTTGAACGTGTCTGTTTATATTACCCAAAAATTTGTTTTCCATAATAAATTTATCCCCCTTTGTTTCTATCTTTCTTATATTTATGACTAACAAAAGAGGGATATTACTACTATTATTAACTTTTAAAAATATTATTTCTTTAATAACATTTAATAAATTTTCTAAAATTACTACAGATGAGGTTGCCCCTTATTAATTAAAATCTAATTTTTAAAAAATATCTTCTATAAAAAAATATAAAAATTTTACTACTTCTTAGATAAAGTATCCATCATAACTGCGCTTATAGTTTTTCCATCTATTACTTCTCCATTTTTAATATACTCCTTTAATTTGTCTATACTAATTTCCATTAAATCTATAAATTCATCTTCATCCTCCATGCCTTCTTTACCTTTATAAAGATTAAGAGCTTTATAAATATATATGTATTCATCTGAGAAACCTGGGGATGTAACTATCTTTCCTAAGTATTCCATATTTTTCGCCTTATAGCCTGTTTCCTCTTCTAATTCCCTTAGAGCTGAACTTTCTATCTCTTCTCCCTTTTCTATTTTCCCTGCTGGTATCTCAAATATATCTTTATCTATAGCTTTCCTAAATTGCTTTATTAAAAGTACTGTGTCTTTATCTTTATAAGCTAAAATTGCTACTGCACCTGGATGTTTTACAATTTCTCTAAAAGATTCTTTACCATTTGGTAATTTTACCTTTTGTTTTACAACATTTATTATTTTCCCTTTATATATTTCCTGCTCTTCTAATGTTTTTTCATAAAAATTCATATCAAACACCTCTTTATACTAATTCTTAATTTAGTCTTATTAAAATTAATTATAATTTATTTTCTATTAAAAAACACCTTCTATGTACTATATCTTCTAATATTTCTACCACATGTGGTTATGTATGTTATTATTTATGAATTGCATCATCTACTGATATATCTATCATACCTCCCAAACAAGAACAATATAACCTTTATATCATATATCTCTTATATTTATTCCTAAGGATTTAGATAGTGTTGGACTTTGTTTTGCTTAGCAAACTTCTCCATCATTAGTAAGACTCTATATAATTCCTATCTCTCAAACTAGACTCTGCATAGATTTCATCTAAGCATAAATTTTCTTAGCCTCATCTAGTATTTCCTATTACCAAGCCTAGAGGTAACTTTCACTGTCAAATTGTTGCCAAAGCTTAGAGCACTAAAAAATAGAAGGGATTAAATTTAGTATCCCCTCTATTTTTATATAAATTATAACTTATAAATTTTTAGTTTTACCCTTTTCACTTTTAATAACATACTTTTTCTCATAGGAATTATACATTAATATAGCAACTATGCTAAAAAATATAGGTCCAATAATTGAGAATATTGTATCTGATATATTGCCCTTTGTAGCCGGTTCTATTATTGTGAAAAAATTAGCAAAAGCTATAGTAAATGTAACTACAACCGCAGCAATAACTGTACTTTTCCTAGTTTTATAAACTTCAAATGGTTTTTTTATTTCGGTTTTCTTTTTAAAAGAAATGAATGCGCTTGATAAAAACATATAAGGTATAGTCATTGCAACGTTGGTCATAAGAATTAATTTTCCAAAAAACTTAGCTGCTGCGTCTCCTCCAAAAGATACTAATGCAATAAATACCACTACAATTATACATTGAACACGCATAGCATTTAAAGGCATGCCGTTTTCAATTTTGGCCATTTTTTCCAGGCCATAATTTATTTGGAGTACCTTCTATAAGTTGTTTTAGTGGAGCATAAGATAATGTAAAGAAAGCTCCAGTTAAAGCTAAAAACATAGAAAATCCTACAAATCTTGCGACCCAATCCCCCATTAATATTGATGATGCTTCGCTAATTCCAAAAGAATGCCCTAATTGATATCCTAAATTATGCATTAGTGCATATGCTATATTTCCTATATTTACGTCTTTGGAAGCTAAAACACTATCCCAATTTGTAACTATGCCACATAAGAATATCCCAATTGAATATCCTACTGCAATGATAATAGCTGCAATAGTAATTCCTTTAGGAAAAGTTACCTCAGCGTTTTCAGTTTGATCTACAAGTCCTCCAACAACTTCTATACCACCATAACCAAATATAGCAAAAACTATAAAAGCTAATACAGAAATTGGATTCTGATATGCAGGATTTGGAGATTGTACAATAGATTTAACAGAAGTTATAGGTTCTGCTAGTTGTCCACCATTTGCTATAAGGATAATTATCGCACTAACTAACAAGACAATATTTAAAAGTGCAACTGCAGTTCCTCCTATAGAAGTTACTTTAGTTATTTTTTCTAGTCCTTTAGAAGCAGTAAAAGTTACAAGTATTATCCAAATTATACCTAATACACCTAAAACTTGAGTTGAATTTAATCCCAAGAATGCCCAAGTTGAAGTAGTATCTTTACCAAAAATTGCATTTGAAATTGGAATCCATAGTGTGGAACAAATGTTAACCATCCAAATTATATAGGATGCATACCACATAAAGGTTCCTACAAAAGCATATTTTGCTCCTACAGATTTTTCCATCCAGGAATAAATTCCACCTTTTTCATCCTTAAAAGCCGCACCATACTCTGCCATCATAAATGCATAAGGAATAAAGAATGTTACACCAGATAAAATATACCAAGGAATAGCACCATAACCCATTAAGTAAAAAGATCTAGGCATGTTAGCAAAGCCAAACACCGAAGTAAAAATCATTAATATCAATGGTATCAAAGTTAACTTTTTAGTTGTTTGTGAATTTTGTGACATATTTTTCCACCTCATACTATAATTTTATTTCTTACAATTTAATTATAACCTATATCTTTACAATTTCAATATTTTGTATTTTTTTCTATTATATTGGTGATTCCCATTATTTTATGCTAATTGTTCAAATTTATTTTCCATTTTGTTCTATATTGATAAATATTTTTCAATATTCTAATTATTTTTCTAAAATAAGCCTTCAAATTTTATTTAGTTATAGTATGTATAAAAAATTTCTATAACATGTTAATTACTTATAATTAAATTTAATAACTTTGCAATTCAATCTTTATGGTTATATTTATTTGGGAAATAATTGCATTCATGTTTACATAAAATATTCATCATAATCCTCTCTAATTATTATTTTTTAATCATTAATAAATAATAATTAGTTTATAAACAAATAAAAGCTCTAGATTTCTAAAGCTTTCTTTGTTTGTAAAAATGGCTTTACTTTTAAAATATTGATTAAATTGTTTAACAATAAGCTTAACTCAATGTAATAGTTTGTTCCTAGGGGTTATAATAGTTGGCGTGGACTTCGTTCGTATTATATAAAGGTTTATTCAAACTGGGTAAATCGTTAACCAGATGGTAGTGCAATAGGCCCTGATGAACCTTATAGCATAGCTTGTGATGATCGCAAAAACAATTAGTTCATATATAATAATAAATATATATATTTTTCCATGCAAAAGAACCCCTTTATTGGGGTTCTTTTGTTTTTTTTGGGAAGTATCTGCTTAACTTATAGAAAACCATTATATTTAACATTCTACAAATGTTAAAAAATTCCTTTATGAAATTAAGATTTTATTGAGGTATTTTAAGAGTTATTTGATTTTCTGCTACAACTTGTCCAGAACTATTGTACCCTTTAACTTTTACCTTATACGTAGCCCCTTTAGAGAAAGTATATCCTCCATTTCTCTTTGTTATTACTTTACTAGTATTTTTATATAATTTTGTATAATTTAAGTTTGGTGGATCTAATGCAAAAGACCAAGAAGCACCAGTGTCTGAATCCACCCATGCAAATACTCTTGCAATATCTGAACTAAAATCTCTAATTATTAAATTTAAATCCTGGAGCACCATTATAATTAGCATATCCGCCACCATCTACCTTAACATAAGATTGTGGTGTATTTATAATTCTTCTTCCAGCATAAAAGCTTCCTATATATGAAATTTTTACAACATCACCTGTTTCTGGTGAATGTATCATTTGTCCATTTCCAACATATATGCCCACATGACCTGTATGTGGAAACACTAAATCTCCTGGTTGTAAATTACTTTGCGATACTGAAGTACCTACATTAATTTGTCCATACGTATCTCTTGGTAAATTTATTCCTGCTGCATTTTTATATACATATTGAACAAATCCTGAACAATCAAATCCTGATGGATCATCTCCTCCCCAGACATATGGAGTCCCTCTAAACTTCATAGCGTAGTTTACTATATCTTGTCCAGTTGCTGCAGCTTTAACATTACCTACATTTAGTAATAAAGCCATAAAAGCAGCTAGAAAGATACTTAATATAGTTGTCTTCTTTTTCATGTTTATTCCCCCTTCTCATGTGTTTATTTTGGTGTGACAACCTATAATTATTACATTTTTTACAATTATTTTAATCCCTTCTTTTTTTATCCTTCATATTTTTACTTATTTATACATTATTGTATACTTTAAATATAGCTTATTATATAGCATCAATTTTTAATTAAATAAAATAATTATTCAATTGAAATTTTAAATGTAACATTAATATATAATAAAAAAGAGCCCCCACTATATGCATGGGCTCCTTTTTATTCAAGAAGGACTTGATAATGAGTTATAGAAAACTATTATATTTATATTCTATACATGTCAAAAAATTCCTTCTACTTCTTTAAAATTAATATCTTATATACTTACCATAAACATAACTTCCATATGAAGGTTAATAAATATGTATCCATTCCTCCTCTGTTCTATATAATCTAACCTTTGATCCATTTGGTAAAGCTCCTAATATTCTACTAGATCTAGATTTCTTTTTTCATAAATTTACACTACCTTGTCTACAAATTGCAAACAAACATAATATATTTGTTTAAAATATATTATGTTTGTTACAACTTAGTAATTTATTATTACTGTTTTTAAGAAATGTACTGTTTTTTACAATGTTTTTTATTAAAAATATGCAAAAATAAAAAGACTGCATATTAATAGTCCCTATTTTACCTTTATAAAATATTTACTTGTGTCACATTATTTATCGAATATGCAACATCAAAAGCAGGAATACTCTTTTAATTTTTGAATAAGAATCATAAACGTTAGGAAGAAGACTAAAAAAGAATATTAATAAATATATAATCAGAGAATTTATGTTAGAGCTACATAAAATGAAAAAGAGAGAATTGAAAAATTAGCAATATAGCAGTGCCTAGATACCTTTAACTTTATTTGTTAATTGCCTTTTAGAGTTATATAATTGATGTTCTTACCACCATATAGTCCAGAATTTAATCTAATTGAAGGGTTATGGTGATGGTCAAAATTATCTGTAATTAATAATATATTTTTTTCTTCTCTACCAAAAGTTAAAATTACAATTCAAAAGTTTATAGAAAATATAAATACAGTTCCTACTCAAACAATAGACAGGCTATGTGTTAAGATGTAGAAACCGTATTGTAATATATATAATTTATTTTTCAATTTCATTTTTAATTCTCTCCACTTCAGATATTAGCTGATTTATCCGTAACTCTAGCTCCTCTATTTTATCAATTTTATTTTTACTAGATGATTTTTTATTATAATCAGAATTCGAGTTTTTTTCTTTACTTTTGCTTGAATTTTTACTATTCTTGCTTGAGCTATTATTCTGAGTAGTATTTTGAGAAGTAGTTTGGCAAAATGGATTATCTACATTATAATTCTGAGGATTAAAATATCTCCCCGGTCCTTGTTGAAAATATATTTGTTGAGCATTAAATGTTACAATTGCCTGGCCAACTAACAGTAACCAATTTCCAAGTGCAGCTTGAACATTAGCAGGGATACTGCCTGCTAATATATCTCCAAGTATTCCTCCTATTGCAACGAATAACTGTGGATTTAAGGATTGAAATCCATTAGGTATATCATAACATCCCATATTGCAAGATTCATTTGTTGCATTATTGTTACTTGTTTCACTTGTATTATCACTATCCTTATGAGAGTTAGTATATCCACAAGCTCTCGCTAAGTCCTCAAAACTATTCCATCCATTGAATTTCATATTTCCTCTTAATATAAGTGTTTATATTTATTGTATTACTTTCCCATCAGAATTGTTACTTTTTCCATAATCCATATTTATTTGCTATTTAAACATATTATACTTATATTATTTATATAATAATCATACTATCTATTATGTATTATTATTTTTAAGTAGGTATAACAATGACATATATAGATAATTTAAATTCTGAGGATTTGCTAAAATTAACAAACGAAACCGCTGTTTCACTTTCGCAAGATAAAACTGTTAATGAAATAAATCTTCTGTAAATGTTATAGAAACAGTACTATCACAACTTCTTAATATTGTGTTGGTTCTATGTGTAGAAAACAACAATTCTGTTTCTTGATATGTGTCTTTAAATCTAATCCAACGATGTAATAATCCAGACATTGTGTTACTATAAAAAACAACTCTATCTTTACATCCTTTATTGATTTCTGCTGGAATGAAAATAGTTCTTATACTAAAATCCACATTGTTTATTTTTAAATGTAATGTTTCACTTAGCCTCATACCTATATCCATTATTAAGTTAATAACAATATAGTCTCTATATTCATGAAATTTTCTAATATTTATTGCTTTTATTAATTTTTTAAATTTTTCATCAGTTAATTGTTCTTTGCTTTTTTTTCAATTTTTAAAAATTTATATTCATATACTGTATTTTGTTTGATTATATAATTTTATAGTTCTATTAGATAAATTTTTATAACTGTAATATCCTAAAAAATCTTCAATTAAATCAACTATTTTCTTTTATCTTTTTATAACTTTTGGCAAAATAAAAACACCTCCTGTAATATTAGCACTTAATCTAATGTATAAAAGGCATTTTTATATAATTTAATTTTAAATTTATTGATATAAAACAATAAAATCCATAGCGATTTTTACAAAGTTTACCGTATAAGATATCTAACAAACCCATCAACTAAGCGATTTATCAAACCCTATTTTTTAACCTTAATTTATCAGCTACCATTGCAATAAACTCAGAATTTGTTGGTTTTCCCTTTCCATTATTTATAGTATATCCAAATATTCCAAGCCATTGATATTGCTAGGTTTAGGTAGGGTTTTAGCAATTTATATGTTTTTCTTTAAAAATAATATACAAATAAATTTTTCATTCATTTATAGGTATTTTTTTAATTAATTTATACGTATTTTGTAATTGCCTTTATTATACTATTATTGCATGGTAATAATCAAGTTATCTTATATAAAATACACTTCATAAAAATAACAATTTCTATGTGGTATACAATACAAATTTGTAAATTAGAGATGTTTTAATATTCTATACTATTATGTTCTGATACACAAGAAATAAAATAAGGTAAAGTAAATTAATACTCTACCTTATATAATGTAGTAAAAGCTCTAATATTTTTTATAAATAATTATTTAAGATTAAATTGTATTCCTTTATTATGCTCTGTTATTAATTTTAGATTATCAATCTTAACATCTTTAGGTATATCGAATACTAAGAAAGTATTCTTGTTTATTCCTGCATTAATTTTATCATAAGACCCTATAAAATTTTTATTTTCTCTAAAAATAGATTCTTGACTATTTAGATGCCCTAATGCTTCAAAAGAATTATCATCAACTTCATATGTTTTTTTCCCATCATTTAATTTAAATTCATGTGGTTCATATCCTGTAGCTTCTTCGCCATTATTTTTTATATCTAGTTTTATTACTATAAATTTTCCACTTGGTGTTGATTTCCCAGATTCATTGCTAATAGCACCATTTTCTTTAGCTTCTAAAATTTTAATACTTAAATTTCCTACAGGAGACTGTTCTCCAAATTTTACATCTTTCTTTTCTTCTTCTGCTTTTTCTATTGTGCTAGAAACTTGTTTATCTACACTTTGACCAATTTGTTTATTAACTCTACCAATTGCTGTAGCATCACCTATAAAATACCCTGCAATAAATATAATAAGTCCGCCTATTATTAATTTAAAATTCTTTTTCATGTCCTTAATCCCCCTCTTGTTAATATAGTTTAATTATAACAAAAATGTAATATTTGTAAATAAAATATCAAACTTTGGATATATTAAGAACAAAACAATTTACAAAATATCATTCAAAAAAATATAACTTAATATTTTACATACTTCCCATAAATATATCCACCATGTGAAGGATAATAAATATGTATCCAATCTCCCTCTTTTCTATACAATCTAACCTTTGCTCCATTAGGTAAAGTCCCTAATATTCTACTAGAAGTCGATTTCTTTTCCCTAACATTTACACCACTTGGGGTACATATAGTACCTGTTTTACCATCTAGATTAACCCATCCATTATTTGTAGATGGTTGACTTGGTATACTATTGTTTGTAGTTTTTTCTACTAGTCCTTTAACTATAGCATTAGCCATATTTTCGGCATTATATCTGCTCATATCGTTTCTATTATCACAGAAACAACATTCTATAAGCATAGCTTTAGCCTTTGTATGCTTTAATACATATAAATTACTACCATCTTTTATACCTCTATTTGTATAACCTAAAGTACAAATATTATTTAATACTCTTGACGCTTCTGTAAAAGATTTTCCTCCATAAGTTAAAACCTCTGTTCCATAAGCACTACCATTAAAAGCATTAAAATGAATAGATACATATAAATCTACATTGTTGTTATTAGCCATATTAGTTCTATAGCTTAAACTATCTTGTAAACTGCTACAAGTATCCTTATAACACTTAATAACTGTATGCCCTAATGCTTGTAATTTACTTATTACTTTTGTTCCTACTTCTCTAGTTAAATTTGATTCTGCTTTTATTCCTACTGCTCCATAATCAGCACCACTTAATGTATGACCACAATCAATCCCTATTTTCATATAAATACCTCCTAAAAATTTAATTAGAAAAGAACAGGTATTAATCCTGCTCTTTACTTTCCTTAACCGCTTGCCTAGCTGAACTTTGCCCAAAATAAAATCCTATTATTAAAGTAAATACAGAAAGAAATTCTGTACTTGATATGTTAGTTTTTAATGCTAATATACAGAATACTATAGTAGTTAATAATGCTATTATCTTTTTTATCTGTAAAAACTGTTTCAGAAACTCCATGTAAACACCCTTTCTATTTAAAAATATTGTGTTGAATTGCATACAAAAAAAAAGCTTACTAAACCTCCTACTGTTAATCCTACATACCATTTTAAAACTGATACTAATTGTTTTAATTGGTCACAAAGATTCTCCATTTTAGCATCTGTCCTGGATTGGTTTTGTTCTATTTTATCAATTCTCTTTGAATGGTCATTAAGCCTAATATCATGAACATTAATTTTTTCCTCTATTCTTTTATGCTTTTCTTCGCAGACTTTTAATTCCACATTACACCTCCAGTAATTAAAAATAGACAAAAATAAAAAGACCTTATATGGTCCCTACTTTGTCTTTATAAATTATTTTATTGTGTCGTCTTATTTATCTATTGTGAACTAAAAAAGACACCTTATTAAGTGCCTTCCAGTTCTTATTATATTATTCCTAATTGTTTATTTACTTCTTTATTTGCCCTATTTGAAGCTTCTAATATTTTTCTATAAAGTAAATTACCAGTATATCCTTGTTTTAAATATTTATTTTCATAATACTCAAATGGTAAATTAGAATTATTAATATCCAAATATGCTGCTAACTCTCTATCTTTCATTAATTTTCTAGCTTGCATTCTATATTTGTTTCTTAATAAATGAGCCTTTATAGCTTGCTCTTTTATTGCTAATGATTTATCTATTTTATTAACAATGTTTTCATCATGGTAAATGTACCATTCTCTTACTTTTAGATTACTTAGTTTTCCAATTAAATTTTCATATTCTTCAAAATTAATATCTGTTCTAACCTCTTAAACCCTTCTTTTTAATATTTGCATCATTTGTATAGTATATATGATATACGAAAATTTGTCAATCTGAAAACAAAAATGTAAATTTTATACATTGATTATCTTTCCATATAGCTTTATTGTTCTTCTTCTATAAACTCTTTTAGTTATTGTAAATTATACAATACATACTTGTTCCGTTACAGCCATAAATCAGTATTATTCCATTATCCAAAGTTCAATCGTCCATTTTGACACCACGTATACATTGAGTTAGTCCTATTATCAAAACAATTACTTCTCCATATCCACCCATACTACTATCGGTACTTATAATAAAAGAAGCTCCAATTAAAATTATTGCAATTCCTAATAAAATGTGCTTAATTCCTTTCAGAAGTCTCACCCCCAGTAATTACAAAATAATCTTTCAACATGTGAATTATCTATTGAGTAACAACTTTTTCTTTAATATCTTCTACATTTAATTCTTGTTTTCCTGCATCTTCTTTTGCAGCTGGATTAACTTTAGCCATTAACTCGCTATACTGTTCCATATCAATTTGGTTAAAAGTATAGAATACATTTAGTTTATTATTCATATCTTCCTTTTCATAGTAATTATTATCAATTAAATTTTTTAATAAATCATACAATATCATATTATTTACCTTCCTTTTCATTTAAATTTTTATTATTTAATACTTCTTTATATTTTAAATCAACCACTTCAGCCTGTGTTTTTAGCAATTCATTTTTTAATTTCTCTTCTTCTGTTTCTGTGTGCTCTCTATATTTAGCTATTACTATTAAATCCTTTAAATTTGTAGCATCTTTATCTTTAGAAATATCTATATGATATTCTATTGCTTCTTTAAAATTATTTTCATTATAACCATATGGTAAGTCTAAAAAATCTATTTCTTTTGGTCTATGAGATATAGGAATGTAACCTTCTGTATTTATATAATTATTTATTACAGTTCCATTTTGTTTATCAAAAATTATTCTATAACCAAACATAATTTCACCCCTTTTTTATTTTTCTATGGCTATCCAATTAAGAGAACTTCTTAGTCTATCCGATATATCATATAATGGTATTGTGAGATTATTCCATTCCAGATTTATGGTATACCCATCAATCTTTGTACCGCTGCTATAGAAATGGAAATAATCCCTCCAACTGTGATACCCACTTATGTCATATTGAGGAAACCCAGAGATTAAAAAATCCTTTGCTATATTTAAATGTACTTTATTACTACTACTAGTGGCAGTAAATTCGTCCAAGTCCACAGCGAAAACTCCTACTTCAAAGGGACAACTTATTTGTTTATTAAAAGTCCTATTGGTTATATAGTTCATACTGCTAGGATTGTCACTAGGTTTTCCACAGTATGACCTCACTTCAGACACATAAATTTTACCTGTTATAAATTTTTTACCATTCAACACCAAATTAGCACTATTTAATTTAGCAATTAAATTGGCTACTCCATCTGTATCTAAAGCGTTTATTCCTTTTGCAATTAAAGCACTTTTTAAATCTGCCTTTTGATTTAAGCCTTGCATATTTTCAAGTGCTGTTATTATTTCACCTATTTTTGCTGTATTATCTAACATTATTTAACCACCTACCTTTATATTCCCCATGCTTCCCATGAGTAGCCATCAAGCTGTAATGCATCTTGATTACTATATCTACGTTGTAATGAAACATAAGTATCATATCTCCAAATAGCTATATTATTATAATGATCAAATTCGGCTTTTGGATAACACCATATAAGAACATCATCACCTTTAGTTAAAGATATAACTCTAGCTTTAAAACCTGTATTAAGGGAATAATTATATTCATTACCTTTGAGTATACCCTTTGTATAATTAGCACAATTTGATGATATAATAGCATTTTGTATATCTATCCAAGAACTATCAGTTTTTAGAGCAGTTTTTAGTTTATTATTTAAAGAATTAATTATATTAGTTTTAATAATAGATTGATTAGCTTCTGCTTTATTTACAATATCCACAAGTTTCTTTTTATCTTCTTTTGTTAAACCTTGTAATGGAATTAAATCTCCTATTTGTAAACTCATACTCCTACCACCTCTAAAAATGGCTCTCCATTAATTACAACCAATTTATATTTTACATTTGTATTTCTATCTTTTAATGTCGCCATATCAGCCAATTGTAACTTATTTTCCGATATTTGCATTTGTAGTCTTGCTGCAATATCTTCGCTTGGATCTAGAGAATTTTTCAAATCATCTACCCAATCAGTAAATTTTTTACCAGTAGCAATTTTAAATTCATTTACCCATTTTTCAAAGTCCCCTTCATGTATATTTTTTTGCTCATTAAACCATGCTTGAAACTGACGGAAAATTTCTGTAGTATCAGCTTGCTGAATAACACCATGTACTATCCCACAAAACTCTTTGTTAAGTCTTAAATCTGTAATATTGCTTTGTATTATACTTATAACACCATTCTTTACATATACATCTGCTAAAGCTATTTCGTAAGCGTCCGAATTCCTTTGTAGGGCTGGAGCAATTGGAGAACTTCCGTAATTACCTTTTTTTAATATAGGTTTTATTTTTCTATCAAGATAGTCTAATCTTAATACCACTCTATCTATTCTGCTAAGTACACCATCAGCTGGATCTAACTTGAAAATATAATCATCAGTATTTTCAAAATCACGACCAAGAATATACCCATAACCTTTTTTTATTCTTATGCGCATATCACCATCTACAGCAACTACTTGTAAGCCTGTCGCTGGATTAGGATATACTCCAGTTCCTATAAATTTAGCAAAATATCCTGCAAAATCTTCTGCCAAATAAGCTCTATCTGGAACGCCATTAGCATCATAAACAGCATTAAAAGGAAAACTTTTTATCATATATCATTACCTCACTTTCTGTTTAATTTTATCTATTATTGTAGGAATATTGTTACCAAAAGTAACATTAACTTCTAACCCTTTTTCCTCATATACTTCTTCTATTTCTGTTATTCTTGTATCTATTCTTACTCCCCACTTCTTATCTACTACAGTTACTATGTCTCCTAGATCATAATCTTTTTTATAAACATTATTTCCATTAGTATTTATCTTACTATCAAAGGTTTGGATTTCTTCACATTCTGATAGTTTTTCTTTACCTCTTTGAAGTAACAAAGGCTTATACCGTTCCCAAGGGATTTCAACTTCCTCTGTTTCTTCATGTTCTCCAGTAACATTACCTTCCTCGTCTTTATCTACTACTATTTTTTTCTTCTCTTCCTTATCTGTTATATCTCTTGCATCTACATACACCTCAAATCTATCTAACCCTTTACCATTTTCTATAGATGTTATTTTTCTATCTTTGCCTTCTCCTGCTCCAGCTATTAAAGTTGTATTTTTATAATTATTTAAGCTATCCATGTATTGCTGTTCTAAAATATTTTCAAAATCTCTAGAAAAAATACAAGGTGCTATAGTTCCGTTATTTATGGTTCTATCAACACCTTTATATACATCAAATTTAATTAATCTATTTTTTATATCTAGTAAATTTCTATATCCTAAGTTAGAAGTATTAGATATGTTTTCTAATTGTTGTAAGACATTTCCAAAGGAATTTTGATATTTAATATCTTTATTAAATCCTTTTAAACTTCCAAGAGTTAAATTTTGGATTTTTCTATTTATATTAGTTGGATTAATAGCATTTTCTAGGACTAAATTTCTCATTAACACTTCTGCTTTTCCATCAAAATTAACTCTATCCCAACTGATGCGCCTATCTAAATAATTAGTTAAAAACTTACCTTTAATCTCTAAATACTCTTGTCCATCTTCGCTTATTTTTAATTGTCTGGTTTCTATATAACCAGCTTCAACATCATTCTTTTTAAAAATAACATTTTCTCTTTTTAATAATTCTAAAGTTTTAAAACCTAAAGGGCAGTGCAATTCAAATTCTCCACTTATATTAAATTTTCTAATCCACCTTAGAGAGGTAAAAGTATCTAATATACCCTTTAATTCTAAATCTCTATTAAATATATATAGCTCCATAAACTACACCCCCAAATATTGTGGACTAAAATATATATTAACCTCTAAATTATCTAAATTATTATCCGCATTATATCGGAAAAGATTATCTCCTACATCTAATTGTAAGAATGTATCTCCTCCACCTACAATATCTAAATAATTTAATATGTCTGTTGTAACCCCATTAAGCTCTTGTAATATTTTTTTCTTACTATAATTAGTGTTTATTATAAATTTTTCTCCTGCAACCATTCCTTTATTTATTTTTATAAATTCTCTAGTATTAACATTAAATAATGAAGGATTTTTCAAAGTACCTCTTGCAAAAAATTCTATTATCATACCTGTTTTAACCTGTCCATTATTTAGAACATTGACTATTAAAGAAGGCTCTCTATGCCCCATTGTAATGCCTTTCCCTTGTGGAATTACTAAAGGAAAATGAAAGTCTCCCTTCCATAAGGCTACATTAACTTTACTATCAATATAATCTTTCCAATATGGATTATGACATAAAAGGCTTATTTGAAATTTAGGATTATTTTCTTTGGGTATAATAGGTGCAGTTTCCACTATACATTCTACATATTTTTTTATATTTCCATCTATATAAATTAATCTAGATTTTAATTTAGGATTTATTATACTTAATAATTTTTCTCTGTTTAATTCTTTATTTTCTGTTATAGCGCCTTGAATAACTATATTTCTATCATCTAAGGTATTTCCTACGCAAGTACTTCCATCTTGTCCCATTCCTTTATTACTATAAATAATATTCTTTAAACCACTTATACCATCTATATTTTCTAGGAAAAAAGGACTCCAAATAGAAAATTCTATCTGTTGTCCTTTCTCATTTTCAAATATAAATTTTTCTTTTTTATTCACATCACCACCTCAATTCTACCATTGTAAACTAAGTTCCCTTAAATTATTTTTAGATTGTCTTGCCATCTCACTTGGAGTTGGTACTGGAGCATATATATGTTGTGTTACATTAACTCCATTAGTCCCTTTAAATCCACTTAATAGGCTATTTGCTACTTTAGTAGCTACATTTTCAGCTGTTTGTATAACTAACTCTTCACTTGCTTCATGATTATATATTCTAGTACTACGTGGTAAATCATATAATTCATATCCTCTTTCATGTAAAGTAGTTAGCCCACCTCCATAAAATCTATCTCCTGTCCATCTTTCATTGAAACCACTAGCATTTCCCTTATTCATAGACCATTCAAAAGTGTGTTTTTTAGGTTTCCATCCGTCCCACCAACTTTTTAATTTATCCCAAGTGGTTAACATATTTCCACTAGTAGTGTCTACACTTTCTCCAATATCTTTATTCATAGATGTTATTTTTTTTACTACTTCCTTCTTTTGATTTTCTGCCTTATCAATACTTTCTTTTCTCTGCCTTTCAGCTTCCTTCAACATCTTGTCAGCTTGATCTTTTGTTATAACTTTAGTTTCGTCTCTCATTTTTATGATGTTTCTAACAGTTTGGTCATATTGTTGATTAGCCTTATCTACAGACCCTTGCCTTTGTTTCTCTGCATTTTTAATAACTTCACTCGCTTGCTCTGCTGTTATTCTTCCATTGTAGTTTTTTAGCCTTTCCATTATTACCTTTTGTTCTACTTCACTGGCAGATAAGGTTTTAACTGCATTTTCTTTCATCTTTTTTTGTAATCCATCTATTGTTTGAGCTTCTTCTGTTGTAATCTGCCTATGATTATTTGCTGCGTGTTGGATAATTGAATTAATTTGATTTTGTAACCCATCTATTGTTTTTTTCTTATTCTCCCAACTAGTTGTAGTTGTTTGTAATATTTTAGCTTCTTCGGTTGTAGTTAAAACATTACTCTTAGAAAAGAAATCTTGTTGGCTTTGTAACTCTTCTGCTTTCTTTTTATCTAAACCAATCTTAATTTTATCTCCCATATCCTTATATATTTTTTGCAAATTATCAGATTGTTGTTTTGTAATTGCAGTACTTTTATTTAAAGTATCTGTAAATTCTTTTATAGTTTGATCCTTCTGTTTTTTTGTAAGCCCTTTAGTTCCATTTACCATTGCAGTATATTGTTTTATTATTTCATCTTTATTTTTCTTAGTTAATACTCCTGTATCAGTAACTAATTTTTTAAAATTGGTTATCATAGCGTTTTTTTGCTCATTGGAAATTTTACTAGATTTTTTACTCATATCAGTAAAATTTTTTAATACTTTATCTTTAGCTTGTTTACTAAACTTATTTGAATTAGCAACTAAATTTAACATAGACTTGCTTGCTTTTTTATCTAAATCCATGTAAGCACCTACTGCTTGTTTAGTAGATTTAGATATTTTAACATTTGAAGTTTCAACACCTTTTGATGCAGCACTATAATTCATCATAGCCGTATTGCTTTTTGAGACTTTATCTGCAAATAGGTCTACACTTGGTGTTGCATCTTTTTTTAGATGTTTATACAATGCTACTCCAGCAATTGTTGCAGCACCAATTCCTAAGACCCAAGGATTAAGAAGCAATGTCACTGCTTTTGTTGCCAGTCCCATAGCACTTATACCTTTAGTTACTCCTGCCGTTGCTACACTAGCACCTCCTGCTACACTTTCTGCTACTTTTGTTGCACCACTTAATTTACCTATCCATTCTGTAGCTTGTCCAATACCACCTACTAAACTTCCTATACCACTTACTGCTTTACCACCAACCTTAAGAAAACTTCCAGTTGCAATAGCCATAGCACCCCATTTAGCTATATTTTTCAATTGTTCGTCTGAAAGTCCACTGAGTTTGTCGCTTAATTTAGACATTAATTCACTTAATTTATCCATCATTGGAGCAATTGCATCACCTAATCTTATAGCTTCATTTTTAATTTTGTTAAGTGATTTTTTAAATCTTTCACCAGTAGTATTAGTAACCTTAGCAAATGCTTTATCTGTTGCTCCTGCACTTTGTTCCATTTTTCCTAGCATTTCATTAAAATCTGCACCAGCATTTGTACTTAAAACTAATGCTGCTTTACCTGCTTCAGCATTTCCAAATAAATCTTTTAAACTAAGATTATTTTTCTTAGCATGATCATTCATCATGTTTAATACATCACTAACACTTTTCCCACTCTTCATTAATTCAGGAAAGCTTTTTCCACTAACAGCTTTTATTGATTTGTCTGCTGTACTACCTGTTTTAGACATTTCATTTAACATACCATTCATATAAGTTGTACTTTCAGCCGCTTTAATACCGTTCTTAGTCATAAGTGCATATCCAGCTGTAACTTGTTTTAAACTCGTATTCGTAGCAACTGCGGTTGGAATGACTTTACCCATTACGGAAGATAGTTCTCCTACTGTTACTTTACCTTCATTTTGTGTAGTAATTAAATAGTCACTTACTTTTGTAACATCTTCAGCTTTCATCTTATAAGCATTCATTATTGTAGTTAGAACATCTAAAGATTGTCCAGCTTCAGCAAATCCAGCCTTAGCTAATTTAGTAGAATTACTTACGAAATTAACCGCATCACCTGTTTTTTGACCTGCAGAAATAGCATCATATACGTTATTAGCAATTTCGGTTGAAGCTATCCCAGTATCATTACTTAATTTAAGTATTCCTTTCCTTAAATCACTTATAGACACTTCGCTTTCATCACTTATAGTACTAACCTTTGCTATACTATCTTCAAAATCTGTAGCAAATTTTAAGCTAGCTATTCCTCCCGCCGCTAAAGGTGCAGTAAATTTTAATATTCCTTCCCCTGCTTTTTCCATTCCACCGCCAACACTCTTTAGTCTTTCACTAGACTTTTTTAGGTTTTCCCCAGCTTTTAACCATTTATTATTACTTTTTTCAAGTTCTCCATTTACCTTTTTAAGTTCTCCTTGGGTCTTTACCATTTGTGCATTAGCCTTGTTCATATTAGTTTCGTATCCTTGAACTTGTTTAGCGTTGGTTTCAACTGCTTTACTAGCTTTTTCATGTTCTTGTTTTAATCTATCTACTTCTTCTTTAGCTTTCTTAGCCTGTTCACTTTCTTTTCCATATACTTTAACGGCTTGCTCATATTTCTTATTAGCATCATCTAAAGATTTTTTTAATTTATCTCTAACTTTTATATTATCGTCTAATCTGGTTTTAGTTTTTTCTATAGCTTTACTATATATATCCACTTTTTTAGAGTGTAATTCTACTTGCTTGCTTAATGCTTCCTGTACAGATTTTAATTTTTCAGAATCTTTACCAAAACTTTTAATACCTTGACTTGCAAACTTCAATTCTGCTTGGTGCTTTTTCATTTCAGCGTTAAGTCCTTTTAATTTATCATTATATCCTGTACTATCAAGCACCATCTTTGCCGTAATTCTTTTTTCTGTATTACTAGCCAATTAGTTAACCTCCCTTCTATAAAAATGCTATATCTTCTATATTCACTTTTTTATAATTTATATCACTTTTAGTGTTATTTTCTTCATTATTATTTTTAACTTCCCAACCATTAAATTTAATATGGTTTTGCCACATCTTATATATTTCAGCATGAGTACTATTCCAAAATTCCTCTTTGCTATAATGTAAATGCACCTTTGCTATATAAAAAAGCCAGTCAAAATCTATTAAATATTTAGATTTTGACTGGTTATTTAGTTTTTTTCTTTTTTAACTTCTTTCTTTTCTGCTCTTTCTTCCTCAGTTTCTTCATTTAATCCCATGTAGTCTAAATAAATATTTACTGCTAACACAGTTATTTCTTGATATTGCTCTGCTGTCATCGTATTTTCTAATTCTTCTATATCCCATTCTTTTTCAATACAACTTAAACTTATTAATTTCAGAGTATTTGTATAGAATTGTTTTCCTTCCATTAATCCCAAAATTACATCACCATAATTACCATACTTTTCATCTATCTTTCGAATTGTTTTATTAACCATCCTAAAACTATATTCTTTATCACCTATTTTTTGCTTTCTTATTTTATGTAACATATAATCACCTCAATCTAATTTTTTAATAAAAATAAGGGTAGAAATCAATCTACCCTATAAATTATTTATCTAATATTGCTTTTTCTGTAGTTTCAACCTTTTCTGTTGGTATTATTACCTCTTTAAAGAATTTTTCATCTGTCATACCTTCTTCTTCATCTACTTTATACTTCCATCTGCCATTAAAATGTAATGGAGCAAATGTTGCTTTTAATTTTTTTGCTCGAAAATTAGACTTTCCCTCTTTACCTTTATACTGCTCATCAGAAATACTAAAAGTACCCTTGTACAATATTCCGTAACGTGCTTTTCCATTACCTTTGTTAGCTTTATAAAGTAAAGCAACATCGGGTGCTTTATCGTCATCACTATATATAATTCCACCTTCTATTGCTAATTTATGCCCAAGTAAAAAAACTTCATTTGCCGTATTTAAATCTGTTATATCTGCTTCTACATCAACATTTGCTAAAGTGCTTTCACTTAGCCATAACTTGTTTTCGGCATAAAAATCATCTGTTGTAATTTTAGGTTTTATACTTAGTTCTTTTATTCCTTCTAAATATATTGGTGTATCAAATGTTACTCCCGTATTATCATCCTTTATTATCTTCGCTGCATATAATTTTTCTAAACCAACTACTGGCACTACTTGTTCTGCCATATTAAAATCCCATCCTTTCAATCTTTAAATTAATTTTTTCACATAATAAAAAAAGACTAGTTTTAAACTAGTCCATTGGTAAACTTACATTAAATCTCATTGCACAATGGTGTAAGCCAGTTTCCTTCTCATAAAGGTCAGCTGCCATATCTCTATTAAATCCATTATGTATCATTATTTTTTTAACTACATTTTCTAACTCTGTATAATCTCCAGTAGAAAATATATCTAATTGTACTATGTATGTTGTATAATCCTCATTACCTTCGCTATATTCTACTCCATACTCATTCACAATCTCATACTCAAGATATAACTTTTTATCAGGATTCACCGCATGTAAAAAATATACACGCTTATCTGGTAACAAATCTATAATTTCTTTATTATTCAATACATTTAAAATATATTGTTTTATATTCAATCATCACCACCTACTTTGCTTTATCTAATAATTCTTTTGCAACTACTTCAATTGCTTCATTTTCACTACCTTTTACCGCTCTATCGAAAAAACCGACATGATACTTTTGCTGTGAAGTACCGAACTCTTGAAATAAATCCCACCAAGCTCCTAATTTTACAGTGCCAACAGTTGCAAAACCTTCTTTTTTAACACTTTTCTTTATTTTCTTAAGCTTTCCTGTTAAAACCGGGGTATTGCTTTCAACCTGTTTTGCTACAACTTCAATTCCTTTTCTTACTACTTTCGTTTCATCAGCTTCATCAATAGTCATATTCTCTAGCATTTCAGTAAACTCTTCCATACCCTCAATTTCAATACCATCAGCCATTAAATCACCTCAATAGCCTTTATCTTAAGCCATTTATTTTTATATTGTATATTATCTATAAAAGTTATATCAAAATATCTATATTTATTTTTTTCTTTTGTAGCATTCTTATCTTTTATAGTTTTGATTCTATATTCTTTAGTATTTATATTTTTTAAATCTTTAGAATATCTAACTATAAATTCTATTGTATTTTCAGAATTTGTAGCCTTTGCTGCATAAAATTCTTTACCCCATAGATTATTCATGCTTGCCCATACAGTTTTATAATCATCCCATTCTTCTATATCAAATCCATTTTCATTTTGTGTTGTAGTATATTTTTGAATAGTTATTCTATGTCTCATTTCTCCTGTCTTAACTTTCATTTTTATCACCTACATAACAATAACTTAATTGTGCAAGTATATAACTTAACGCATTTTGTGTCTTTATAGTTAAATCAGCACTTCCTCTATTTTCATACCTATCACAGATAAAAATTAAACACGCTAACTTTGCTAAATCATTTCTATCATCAAATAGTTTTCCTGTAGTATTTTTAATATATTGCTCTGCACTTTTTTCCAATAGCTCTAAAAAGCTATCTTCTTCTATGCAATCTGATTCTATCCTTAAATACTGTTTTATTTCTTCTAATGTTACTATCAATCTAATCACCTACTTTATTAAAAAAGGACATAAAAAAAGAACCTATATAGGAACTTAATTTATATCCTTATACTTATTTTTTAGCTATTTGGTAGCTTTTTCAACAACTGTTGTAGGAATATAGGCAATTATTACAGCATCCTTATCTACAATTCCCCCATCCATCTTATAGATTAATCTAGTTTTAGTTGTATTAGATTCAAAAGAACCACCACCAATATTAGTAGATAAAAGTTGATATTCTCCATCAGAATAATATGTATATAAAGATTTTAAATCACCTAAAATTACTGGAATTTTACCATCCTTAGTTTCTAATACTTCGTTTGGTAATTCAACTACATTTTTTCTTAATAATTTATCAACTTCATCATTCTTAGGATCTGGTCTTAAATAAGAATTACCTTGTTTATCCTCAAGGCAATCTAAGAAATTATATCCATCTTGATTAGTAACCCAAGTTGCAGAAGTCTTATAATAAGAAGGTAATTCAACATTTATTAACTTTTTAAAATCTTTTATAGTTGCTGTTGCTGATAAATCAATAACTTTTATATCCTTATAAGTCATTATTCCTTGTACTTCATTTTCTCCACCAGTACCATAAAGTACTTTGATATTTTTAGTAAATCTAACTTTATCTACTAACCATTCTATTATAAAATTCTTTAACCCTTCTCCTGCAAATTCTAGTAAATCATTTGGGATGGTTTTAAGTCCTGCACAATCGTGTAGTTTAAAAGAAATTCTCTCTAATTGTCTATAATCTACTTCTTGTATTTTTCCATACTCATCAAGATTAGTTAGTTCAGTTTGCTTTTTTCTCTTTTCATATGTTCTTTGTCCACTTCTAGTATAAACTTTTTCAAAATTAACTAGATTAGATATATCTGTGGTATCTCTTAATCTCTTATTTATTTCAGTTTTTATATCTTCAGGTACTGTAAAGCCACCATCTTCTCCTACATGTTCAGATATAGCCCTTTGTTCCCCTTCATTGAATACAAATCCTTTCTTGTTTCTAGCTTTCAATGTTGCATCTGCAATTGCTTTTGCAAATAAATTCCCATTATATATCACTTTATTTCCCATATTATTAACATCCTTTTCTTCACTTAAATTTTTCATTTTTCCTTCTTTTATTTTATTTTCTACTGATTTCTTTTCGTCAGCTTCCTCCATTTCAGCTATTTTTAACTGAGCTTGTAAATCTTCAATTTCTTTTATTTTTGCATTTATATCATCAGCAGTTTTAAGATTCTTAGCTTCACCTTTCATTTCCTGAATTTTGGCTTGTATTTCTTGTACTTTTGTCATATTACTAATCAATCCTTTCATTTTAAAATTTAATTTTTGAATAAAAAAAGACTATAAATACAATAGTCTAAGTCTAGCTTTTGCTAATTCTAATTCTTCTTTATCTTTTACATTCTCTGTCTTTACTGTAGTTTTCTTATCTTCTAATAGTTTATTTTTAAGCTGTTTAGGTACATTTGTATATTTATTTAATATAGATTTATCTTTTACACAAGCTACTAAATCTTTATCATCTTCAAGTATTTCTATATTAAATATTTCACTCATTTCTTTAGCATTTAGCCATGTTTCTTTATCAACTAAATTTTTTATTTTATCTTTTGTTATACCTTCTTTAGCTTTATTTAAATATAGTGGCATCATTACACTATTTTCTATTTTATTCAATAAATCTATTTGTTTCTGCAATTCATCAACATTTCCTATACATAAAGTATAAGGATGATGAACCATTAATAAACTAGATTTGTAAGCATACACATTGTCAGCCACCAATGGTAAAAAACTTGCACAACTAGCACCAATTCCATCTATAGTAGCATTTATTGTTACACCTTTTTCTTTTGCTCTCTGTAACATAGCAATAATACCTTGTGTAGTTGTTACACTACCACCAACAGAGTTTATATACATATTTATAGTTTCATTTCCTGTTAAACCTTCTAAATTATCCTTAAAATCATTAAATGTTACATTTGATTCATCCCATTTTTCAGAACCGCCTATGATTTCACCATAAACATATATATCTATATTGTTGTCCGTCCTGTTTTTAAATTCATAAAACTTACTCATTATCTATTTCACCACCCTTCTTTTTAGAATTTGCTTTCGCTAATTGATAATCATTAGCTACTTTTATATCAACATGATTTAAGTCAACTCTATGAGTATCACCTTGAATACCTATAGAATTCATATTTTCAAGCTTTCTTACTTCATTGATACTATATACTCCTAAATTTATCATTTTTTCGTAATAAGTACTTCTGGTAGCACTATCTCCCCTTAAAGCACCTTCCATATTAAATTTAATAAAATATTTTTCTCTTTGTGTACTACTAAATAATTTATAATTAAATTCTTCTTCAATTTGCAACAGTAAAGGTAATATAGTATTCATATAAAAGTCCAAACTCTGTTGCTCTATATTATTAAAGGTACTTCTATCAAGAGAATTAATCATATGCAGTGGCACTTTAAATACTCTAGCAATTTCTTCAAGTGTAAATTTTGTAGATTCTAAAAACTGTTGGTCAGTAAATTTCAAGCTATTTATTTCCTTATATTCTAGTCCTAAATCTAATACAGCAACTTTACCAGCATTATCATATCCACTATTATTTTCTTCCCATTGCTTTCTTATTTCAGTTTTTGCATCAGTATTAAGATTACTAGGATAAGTTATTACACCACTTGTAGTAGTACCGTTTTTAAAATAATTACCCAATAATTTTCTACTACTTTGCATATTTCCTATAGTTTCTCTAAGTATATCTATTTTACTTTTTCCTAATATTCCATCTGTAGATAAACTTTTTATATGTATTATTTCATCATTAAAAAAGGTATGAGATTTATTATTTAGAGTTGCTTTATATATAATTTCACCCGTTGTAGGATCTTGTAGAACTTGTACATTATTTAAAATCCAAAGATTAATTGCTTTACCTCTTCGCCTTTCTACCCACACATAAGTATTACCATCTAACAATAATTTAACTGTTAATGTATGTTTAAATGTACTAGGCGTCATATATAAATTAGGTCTCTTTTCAAGTAAATAACTAACATCATTATCAACTCTATTACTGCCATCTTTATTTTTCTGATATATGTGAATAGGTAACTTAGAAATAGAGCTTGCAATTATATCAGTACAAGCATATACACCACTAATTGTTAAAGCACTTTCTTTTGTTACTTTCTCTCCACTTGTTGTAGTTCTACTTTTTATTAAACTTGTAAACCAATCACTCTGATTTACTGTTTCAGTTGTTGTATTTTTTATAGCCCACATTTTATTAAATATGCCCATTTATTTCACCTACCTTTCTATAGTAAATTTATTAATATAATTATTAATTACTATCCTTTTTAGGTAGTTTACTTAGAATTAAACCTATCAAAATCAAAATCGTTGACAGTGCTATCATTCCACTAAATTTACTTACATAAATAAAAAAAGCTGTAGTTAATATACTACATCCTCCCAAAATCAATATATCATCTATATTTTTCATTATAAAAGTAACTAGCATCATTAAATATTGTTTAATTATTTTTCCTATAGTATCCACTCTCCCTTCTTAATAAGTTCATTTAAATTAGGTTTTTCTTCATGTAGCCAAGCCATTTTAAAACCACAAATTAAAGCATCTACTGGGTCTATTTTCTTTTTAGTTGCATCTTTATCTATTTTAATTAATCCATTATTACTCTTTATTACTGCATTACTCATAGCAAAATTTAGAACTGGATTAGGTAAATATATTACATTGCCCATATATACTTCTTCTCTTAAAGCTACTGTACTTTCATTTAATTTATTATGTGATTGGAATAATTCAGTAACATCATAGCCCATATCACTTATATCTAGCATTATTTTCGTAGCATTAGCAGGGTCAAAACACCATGTATCAATTTCCCAATTATATCTTTTACAAAAATCTATAGCATATTTAATTACTACATTTTGATCTACTATTGGAGTATTAGTTATAGTTATATACTTTGATTTGCCATATTCATCTTTTATTCTTTCCCAAGCATCATAAGGGACTTTATCCTTTAGCGTTCTTTCCATTAATTTTTCTCTACTTGGTATAAAAGAATGACTAAATATAACATACTTTTTAACTCCATTATCCATTATCGGTATAATAAAAGCTAAAGAAGTCAAGTCTATTTTAGAAGACATATCTCCTCCGATAAAACATACTCTATTGTTTAAATCATATGGAATTTTTTTTATCTCACAAGCCTTCCATTTAGCCATATCCATATAACTGTTTTCTTTTGCTTGTACCCATATATCCAAACATTTAGTCATAAATGAGGGCATTTTTTCTGGTATTTGCTTTGCTATTTCATATTCTTCTTGTATTTTTTCTTGTCCTGCTTTATATGTCATTCGTAAAGGGTTTGCCTTCCACCAATTTCTCTTATTATGTATATCATCTTTTTTATCTAATTCTAATATATCAATAAAATATGTATCATTTTCAACATCTATATTTGGATTTAAAATTTCACTACAATACTTATATTCTTGTGTATAACAGGGACTATTAAGGTCAACACCTGCTGTCGTTATAATCATTAATAACGGTTCTTTTGTAGCTTGTCCATAACTAGCCATGGTATAAAAATCATCTGTAGGGTGTTGATGGTACTCATCTAATATGAATAGTGCCATATTTCCCCCATCATTTTTAGTACCATCCTCTTTACTTAGTGCAATCATTGTACTACCTGTTTTTATGTGCATTATATAATCTCTTGTACATTTAAACTTAGTTGATAACGGACTCCCTTTTAACATTAATTTAGCTTCTTCAAATACAACTTTACTTTGTTTTCTTTTGATACCCGCACAACATATCTCATATATTTCATCATTTCTTGTGCTACCACAAGCTAATTCATATAAAGCTATACCACTTTCCATCTGTGATTTAGCTTGTTTTCTAGCACATTCTATAAAACTTTTTTTAAATCTACGTCTCTCATTATCATTTCTTCTCCAACCATAAATTTGGCATATAAAAAACTTTTGCCATATAGTCAATATTATTGGTTGTCCCGCTAATTCACCTTTACTATGTCTTAAATATGTAAACCATTTGACAATCTTTTGAGCCTCTTCTTCGTCCCAATAGTAAATATAATCTTTATCATTTTCTAATTTTTCTATATCATTTAAAAACCTTTGACAAGCCCATTTATGTTTTTCGCAACTTATATATGTTTCAAATTTACTTACAAAAACATCCTTTAAACAATTATTACAGTATCTAATTAATTCTTCTTTAATGGTCACTTAAATATCACCAAACTCATCTACAATATCTTTTTTAGTTTCTGTAAGTTTAAGAGTTGCTATTTTTAACCTACTATCAATAGTCAATCCTAATAGACTACTGTATTTTTTCATTTCATCAGAATATTTTAATTGTATTTTTATTAGAGGATTTTCTATAACATTAGTTGCTCCACCTTTATTCGTGTATTCTATAGTTAATGGTTGTCCTTTTAATTCTTTTGTAGCTTCTATGTAACTAGAATAAGCGTTACAATAAGCACCCAAATTATTTAAATCTAAATTGCTTATTACACTTAAAGTTTTGAATTGTTCAACTAATCTTTTCCATTCTTTTTTAGCTAAAGAATCCCTTAACCATTTTGGAGGTTTTTCTAATTGTTCCATTCCAGTTTGTATTATTTGTTCTTGTAATTTTTTTTCTTCTTGTTGTTTTTTCTCTAGATGTCCTTCTTGTATTGCTAACATTTTTTTTGGTCGTGCCATTGTAATCACCCCTTTCCAATTAATAATATTTACCCCCTAAACGTTAGTTTTTAGAATTTTGTAAAATGAAGACTGCACCACGGACTTTTTAATAAATATCTATAGAAATCTAACCGTGGGGGATTAATTCAAAAAAATAAAAAAGCACTAACTTTTTAAATTAGTACCAAATTCCTTTTCATATTTTCTTTTTAGTTCTCTTAATAGTTCTTGCATTTCTTTCTTATCCTTAGCACTCCTATCATATGCTCTATGCACTATCTTATGGACTTTATCAGATAAAGGAATAAGATTATCTATATCTAATCTCTTATCCCAATTTTCTTTAAGCTCTATAATGTGATGCATTACATTACAATACTTTATTTCCTTATTAACATAATAACTATATAAACATATATTATTATACTTTCTTCTTACCATATCTCTTACTGGTATCCATTCCTTACTAGAATAAAACTTCTGTTCTCTATTATCTTTTCTATTCTTCTTATATTCTTTATAGCTTTCTTTCTTACTCTTATCATATTTATTCTTACATTCATCACACATTCTTTTATTATAGTCTATTACTTTTCCACACCTGCATAATTTCTTTAGAGCAATATCAATCACCTTCTTTTACTTTTCTATAGTAAAAAACACTCAATTAAGAGTGTTTAAAATAATTTTAATATATTTTATATTGTGTAATTTTATTTCATTATTTAAAACGGATTCATATTAAACAATCTTCCATTATTGCCATCATCATGCAATACTTTAATTATTGTTTTATTATCTTTCAATTTGCTAATTTCATCATTTTTTTTAATACTAGTAGGTAATTCATCTTGTATGACCGTAAAAATATGCTGTATAGAATATTTTTTTGTATATTCCTCTATAATTTTATAAAAGTTATTTTTTTGTCTATCATCTAAACCATCAAAAATTCCATCATGATATACAAAATGGAAGTATTTACTCTTATAATAAGTTGCAAGAATTGCTAAGTCAAATGCTGCACACATTAATTTCTTATAAGTAGTTCCATCGCCCTTATTTCCTTTATAATTAGTTTCACTATCAATAATTTCAGCTTTAAAATTAATATTGCTTTGTTTGTTGGGAAATAAAGTTATTATTCCTAAGTCTCCAAGTGTCGTATTTATAATATATGAAAAATGTTTCTTAATATTATTCATACAACTATTTTCTTTCCCAAATATTTCTTTATTCATATTAAAAACTATATTGGTTCTATCAACTTCTAATTGTTGATTACTCAAATCAATTTTACTTGCATCATCAAAATTCTCTAATTTATCTTTTAAATTTAATATCTTAGCTTTTAAATCCACTATTTCATTTTGCAAGTTTTTATACTTGTCCATTGTATTTGAATAATTTAAATATTCCAAATATTTACTTCTTTCTAAATTTAACTCTTCAATTCGTTTATTATTAATGTCATATTTTTCTTGGCCTTCCTTAATTATTTCTCTTAATATATCATTTCTTTCTTTGGTTAACTCATTATTAAATATAATTAATTCTGTATATTCCTTTTTTAATTGATTTTCAAAATATAATCCTATTTCATTATAAAAAGTCTCTAACTCATCTAAATTCACATTATAATCTATGATAGATTCTTTTGCATTTTTTATCTGTTTTAGTAAGTAATAATTTTCATTAATTAAATTTTTAAGTTCTATATCTATTTCTTCAACTAATTTTTTAGGCTTTTTAATATCACTAGTAACAAAATTAAAATTATTATATAGATTACTCTTATTTTCTAAATCATTTTCTTTTATACATATTAATGTTTTTAACTTTTCTTTTTCTACTATTTTATCTTCATTAGCTTTAGTTAGTTTCTTAATATCTTCATTATTCTTAGAAATTTGAGTATCTATATCATATTTCTCAATTATATATTTAGATTTAAATCCTAATAATTCTAATAATGCAGGTTTCCAATTTTTATCTGGTCCACCAAAACTAGATAACTTAAATAAATCCGAATAACTTTCATCATTTCTTAGAAAATATCCCAAACAACTTCTATAATTACGATTAGCTAAAACATCAAAACTTAATAACTTATTTACATACTCTTTGCCTTTTCCAATATTACCAATAAAATCCCAATCTCTATCCTCTAATTCATTATAATTTTGATGTGGTTCAATATGTTGTTTTATCATTATTTTTTGACCTTTTTTAACTGGTCTTTTTATTGTAAAATATGAATTATCATCTAGACTTATTTCCAAAAAAAATATCATTTCCTCAAAAATATCATAATTATTTTTAATAAAATGTCCTTTTTTTATTTCCTTTAATAAACAATAATCTATTAATTTAGCTAATAATGATTTGCCCAAGTCATGAGAAGATTTTCTTAAATTACTAGGATTTCTTACTTCTGCTAAGATAATATTTATTCCTAAATTAAAATATATAGGCTCAAAAATAGTATCATTATCTGCATATAATTTACTTAACTTCATAATTACACAACCTTATTAAATCATTTTTCTTATTGTATTTTATTCTATCTAAACAAAATAATAATTCAATTGCTAAAATAAAATTTTTAAAACTTGCATTTCCATTTCTCATTTTATATTTTAGGTATAGCTCATTAAATTGAATAAAATCTTGTTCAAGTAAAATATCTATCAAATAAATTGTATTTTTTAATAAAGACTTTGATATATCCGTATGCTTATTTGGTCTTATCTTCATAATTTTCCCCCAGATCACAATAGTAATACATATACGCAATAATTATCTTAATCATATTTTTTCTGATATTGATAAGTCTCCAAATTTTACTTCAATTAACTCAATTGATTTTTTTATAAGATAATCTAGAGCTTTATCAAACTCAGGAAATTCTTTTTTGTAAGCAATTAAAGATTCATTTATCGTTTCTGATATATAAATATACCTTTCATTTTCATTCTCATTTTCAGAATCGCCCAAATAATCTTTAATTTCATTAAAATAAGGTATTCTACATCTAATAACATTTTTATAATAATCTTGTGATATATTATTTATTTTATTTTTTAACTCTATATTAGTCCTTTTTATTTCTTTGTTTTCCTCTTCCTTTATTTGGGAATCAGTAAGTCTTCTTTTTATTACATTCTTGAATTCCTCTCTTGCTTGAAAAAATATATCTATCAACTTTTTTATTTCGTTAGCATCTATATTTATTGGTATGTCCCCTGCTCCAAAAAAAGAACAATTACTATATGTATCTCTTTCTGACTTTATGTTAGGTGAATAGCTACCCATACTTCTTTGAAACATAAAAATTCCCCCATATTATAATTATTTATGTGTATCTCGCCCTGAAATAATATTAGGAGAATTACTTCCTTCTGAATTTTGTTCAATATCTTTAATATCACCAATTTTATTGCTATTATAAATTTTTGTAACCTTGTTTGCTACAAATATTCCTATAAATAATGAAATTATAGAACATACACCTGAAATTATATTAAATGTGTTTGTAAAATTATCCATAATACCCCCAAAATTTTATATTATATTTATTATCTATTCTGTACTTTAGCTAATTCTTTCATTAATTGTTCATCTATAGAATCTTTATTATATTCTATTTTATTTATTAAGTCATCGACTTTTTTTCTTATATCGGATACATTAGTTGCTAAATATCCATCCATTTTAGCTTTTGTATTTTCATAATATCTACCATTTTCTAAATTTCTTAAAATATAATCAATGTCTTCTAATTCTCTTGAATATCTTTTTTTTACATCCACAACCTTTTCCATACTCCCATCCCCTTTACAAATTTCTTATCTAATTATACCATATTTTATATAAATAAATAATAATTTGTAAAAATAAAAAGAGCCACATTGGTATGACTCTTTAAACTATTAATAATCTCTATTTTTATTCTTTGTTGAACTTTTCAATATCAGCATATTCCTCTACAAATCCACAACTTAAACAAACGTATTTATAAATATCTACTACTTTTCCTGATCCCATAGGCTCAAAAACTGTTTTACAATCTTCATGTATTCCCTTTAGCATAGTTCCTGTACATTTGGGACATATCCTTTTTTCTTCCATGCCAATCATCCTCCAAAGTATATAGTTTAATATCTATTTTTTAGATGCTCCTAATGCTCAATCACACTATAATAACCTTCTTCAAATTTTATCTTTCCCATGCCAAGTAATTGTTTCAAATCATCCTCTACTAAATTATTTAAATTTACAACTTCTTCATTGACAGGGAATTCTTCTTTTATTTGTTCTATAGTAACTTTTTTATTTTCTTTTATAAAATATAATAAACTAGCATTATGCCATTCTTCAAATATACCTGCCATTAATCTTATCTCTCCAAATATAAAATACTCTATAACATCCAATATTCTACATTTAGACAAGTTTTCCTTCAATATTTATAATTTTTACCTATATTTTCTACATTCAGATATAACTTCATCACACTTTTCACATATGTTTTTTCTATTATCTTCTATATTATCTATATACATCTTAAGTAAATACTGAAATTCTATATTATTTACATTATAAATCTTCTGTGCTTCATCTAATAATTCTTTTAAATCTATATCTTCTCTTTTTTGTTTCTCTATCGCTTTTTCCTTCGATTCTTTATTACCTTTTTCTCCTCGTATTCTTTTTACAGTTTGTTGTAATTCCTTACACGCCATTTTTATTTCTTTTAATTCATTATCAGTGAAATTTTTAAATAACATACTTATATCCTCCAATACTATTATTTATTTTAATTATTCAACTCTGTAACTACCTGTTCTAAACCCATACCTTTACAGGTCTTTTCAATTAGTTCTCTAGTTACAAATGCACTTCCATATTTTTTAATCAAATTATCTATATCTTTTTCAAATATATTATATTCAAGTTCTCCGATTCTTCCGTTTATTAATATATTATCTTTCACAACATCTTCCATTTATACTTCCTCCATTTTCTTTTTCTTTATAGCTAACGCAACATGTTTGAAACAGTTGTTATATTTCTTCAGATCTGTATGCTCATCAAATTCTAATAATAATTCATGTAGTGTCTCATTATTTTCAAATATAAATGCAAATAAATCTTGACCATGTCTATTTATCAGATCAATTCTTTTTTCAAAAACATCATGATAATAAAGCCAACTAATCTTTCCCCTATTAATCAAAGCTATCTCATTTCTTTCTTCCATACGTATTTCCCCTTTCATTAATTTAATAAAAAAGCTGTAGAAATTTTTTTAAATCTACAGCTCAATCATATATTTTATATTGGTAATATATTTATACAACTCCACTTTTGTCCTGTTCGTATTTGACTAATATAATTTCGATTAATACCAGTTTTTTTACTTATTTCTATATTGCTTAACCCCATCTCTATCATCTGTTTAATTTCTAAAATAGTATCTAAATCATACTTACAATTTGGATTTCTAGTTCCTATATTAGATTTTCTTCTACGTTCTGTTTCCTCTATAGTAGGTTTACTTCTTCTGCTTTTACCATGTTGTTCTTTATTCACTATAGTATCTTTATATAAATTTATATATTTAGTTTCTATTTCTAATCTATCTTCTTCATTGCATTCTTCTAATATAGTAAAATATAAATCTTCCTTATTAAATATTTCTTGCATTTGCCTTTTGTTAGTATTTTTATACTTATCTTTCTCTAAAAAATGCTTATGTCGGCTATAAGAATCGTTACATTCCTTAGAACTTCCTACATATATATAAATCTTATTATTATTCTCTATATAATAAATTCCGTATACTCCGCAAACGTTTATTGTTTTAATTCTTATTAATCTTCTTCCCATAGTTCCATTCCCCTTTTCTTATCATAAATTTAATTTTCTAAGTACTTATTAATCCGTTTTAAAAAAATCGTCCCCAAAAATCAAAAAAAGATATAGAATTTTTCCTATATCTCTTTCACTTATATGTATAAAATTTTTAATTTTCTATTGTATTTACTTTCAATATATGTTATAGTATAATTAGGATTTATTGTATTCATATTTTTAAAAATAAAAAAAGACACTATTATAATATCCTTTTTAGTATTTACATCGTCCTATCTTCTTCTATAATTTCTTTTGCTAATTTTTCATTATATATAAGTCCTGTTCTACATACATATCCAATCTTACTTGTACTACCTAAAATATTTCCGTAATAATCATCTTCTTCGTCATATTCTTCAATTTCAAATAATTTGCAAAACATATCTACATCTACATATTTTTCTATTACATCTAAAGTATCTATTATTCTTTTGTTCAAATAGCACATTTCATTTTTAGTATGATCTAGTCTAATTTTATATTTCTTTCGCATTAAATATAAATCTGTTAATAATTCATCATCATCAATTTCTTGCATTTCTTTATTATATGTATCTATTAATTTTTTATATAATTTTTCCTCATCATATAATTTTTTTGCCTGTTCTTGTAAACTTCCTTTTGTGTTTACCTCTACAATAGCTTCATACATTTTATTATTATCCATATTATCTCCTCCAATATATTTATTACTTCTTTGTTAGAACTTTAAATTACTTACATCTGCACACCCATCTCATCAATCCAAACATGATCTATTCCTTCATATTTTTCATGTAATTTTAAATATATCCCATCTTCTTCTTTTATAAATTGAAAATCCTCTATTTCTTCTACTTTACAAACTATGCAACTAGAATAATCCACTAAATCTAATTGTATTAATACTTCTTCATTATTTTGTTCATGTAGAAAATAAATAAAGCCACCTCCACACTCATCATTATTAAATTTCTTTAGTGTACTTTCTAACTCTTTGCTTTCTCCCATTGTTATATTACATTCCTCATTTATTTTTTTAAATGAATCTTTTAATAATTTCGTAGCATTAATCATATCTTCTGTTAATGTTGTGTTTGTTTGTAAACCTTTCTTTCTTTTTATTTCTTTGTAAACTTTTTCTAACATTATCATAACATCATCCTCCATCTTTTTTGATTTATATTCTTTATATGTTTTTTCATATATTTCCTTCATAAATTCGTTTAACTCATAATAATTTTCCATTTTACTTTCTAAATTATTATCAATCCTAATCAATTCTTTGTTATTGTTGTAAAAATAAACATACTTTTCATTTTGATAAGAATAAGCTCCCTCTTCATTTAAAACCTTTTTAGCATATTGAATTTCTTCAATTTCACTTAATTCCTTGTTTGTAAATTTTCTTAACATATTATCATCCTCCATTTTATTTAAATTATCTTCGTAAAAGTATTGCTCACCCTATAAATATATGTTATAATAAAGGGGGTTTTATAAATATTTTTAAATAAAAAAATTATAAATGTGGTTACTTCTCACCTCACCACATATTTCTCTGTCTTATAACTTTTAGATTTATAGTCATAACTTAGTTTTAAATCTATTCAGATTAGAAGAGTTATTCCCTCCCATATAGAGTGAAAATAAAACCTCTGTACTTATTGACATTACTTGTCCACAGAAAATAGGTCGTGCATTTTTTTCAATATTTTTATCCTAGTCTTTGATACTTAATTCCATATATATCTATATCACCATTTTCACTTCTATATATTGTATTTGTATTAGATTTTACAATAAAACAACTTAAAAATAATACAGAATCCAATTCATACAAATGTCTTAACATCCCTCTTCCAATCCTAACATATTGTATATGTTTTTTATTATCTATATTGAATTGTTCTTTTAATTCTTTAATTTCATCATATCTATGAACTTTTTTTAAATCTTTGGTTTGTTTATTTAATATTTTTCTATTGTTATCTAAAACTTTTATAGCTTTTCCTAATCTTTTAATGATTACATATATAGTTACTTTATTTAATGTAGTTTTATTAAATTTTTCTTTGAAATCAGCTTTGACTTCTTGTACTTGTTTATATTTTTCTTTATTTTCCAATTCATCGTTTTGATATATTTTGGCTATTTCATATTGTTCTTGAGTTACCAATTCCGTAAATTTAGATATTTTCTTTCTATCAGCTTCATTCATTTTTTGTTTGACTAGTATGCTTTTTAAATCTATAGTTTTGTCATTTTCTAGTTTTCTATCAATTTTGTTCATAATTGTAACTAAATAGTCCATTCCAGTATGATATTTTTTCCACTTATAATCTTTCCCGCCATCAAGATATTTAAAGAAAAATGGTCTAGTTTTTTCTAGTAAATGACCTTTAGCTCTTATTTTATCTAATTCGCATTTAACATTTACTGGACTAGATTTTTTGGCTGAATCTATAACAATACAACTTAATACATTTAGATTACTTATATCCTTATACAGTTCCAATAATTCTTTTTCTGTTGCTCCCTTATATTTCTTATTCCAATAAACACTATTTAACATTTGTACTAGATTAATAACTTCTCCTATTTTACCTTCACTACATTTAATATCTGTATCAGCTAAATCTTTTGGACTGTAACTTCTATCTATTTTTGTTTTTGGTGTAAAATCTGTACTTACCAAAAATCTTTTAATGGTTTTACCATTTACAGTTATATCTTCATTTAATCCCTTACATTTTTCACACAATATTTTATTGTTTGTGATAAGGCAAGCGTCTCCATCAAAATCCATAGATGATTCAAGTTCCATAATATTCCAATCTATACTGCTAATAAAAATTACATTGTCTGTAGGATTAAAGTATTTATCAATTAATTTATTTGACTTATTTTTCATAACTGTAACATTTGACATAGTTGGTTGAGGACTTCTTACAGCTAATATATCTTCATCTACATCATATTTCTTACAATAACATTCGTTAGGTTGCAACGTTTCAGAAACATCATCAAACTGATTTATTGAAGCTAATAAATATTCATACGGATTATTAACAACTACTGAATATGTACCGTCTACTAATACATGTCCTTTTTTAACATTCTTGATATAATTGTTAATTATTTCTTCTCTAAATTTCTTACATATTGTTGTATTGATAAAATCTTCATTGATTTTTAACATATTCAAAACAAATTCTGAATTACTTGCAAAATCTTCTAACTCTTCTGTATCTATATCATCATCAATTTCACTTTCAAATATTTCCTTTAATGTTCCATCTTTCAATAACCCCAGATGTAACTTGAATACAGATACATCATTCTTTAATAAAACAATATAATCCTTAGTTGGTTGTAAGAATTGTTTCACTTCTAAATATGTAAGTCCTAGTGTATTAAGTAACTGATAATGTGTACTAGCCATGTTATTAAAATTATGATGCTGTCCTTTATCTGTCTTACATATTCCCCATGTATCTAAAGCTATTTCACACCAATCTTCAAATGTTTTAGTTTTATCTTTCAAATATTTTATAGATGATTTAGTAGTAATAAGTTTTATATCCCTTATATCTGTAGCTAATGTTTGTCCGTTTAATTGTTTAATATCTGTAATATTATTATCTTCAAAGAATTGTTGTATATTCGTATTAATACCGATTCCTTTATAAAATCTATTTCTTAATTGCATGATAGCTTTATCTCCATTACAACTATTAACAAAAATTTCATTATCTAATAAAGCTTCACCGTCACTCAATTTATTAGTTATTTCTTTTGCTGCCACATCTGTATGTAAATCTCCACTAATAATATTTCCTTTATCATCATACTTTTCATTTATTAATTCTGTAGCCATAACTGTATCTTTAAATGTACTTTCTATATCATCAATCAGCAACACATTTTTAGGACTTAATTCAAATGTATCTGTAATACTTGTAGCTATTAAGGATATATAAGCTTCTATACTTGGTAAATCTAAATTATTCTTTTCTTTATATTCAATTCCTGCCATACAGTATTCTATAATATCATTGTAATATTTTTCATTTACAAAATTCACTTTTCCATTTCTAGCACTCCCACTACTTCTATAAAGTCTTATGTATTTAGTCTCTACACCATTTACATTTAGTGTGAATCCATTTGTATATAGCTTTTCTCTTAGTTGTTGTGTGTTTGTATTATAATTAATTTTAATAATTTCTATCATTTCTTCTATATGTTTAATTTTTTCTTTAAATTCATCTATTTTATTATTTACTTTAGTCAATTTTATTTTTAACTCATTTATCTTTTCAACGTCTATTTTTTCTTTTTTCTTTAATCTTCTAATTTTGCTTTTAATACTATTTTTTTGTTTCTTATAAGGTAATTTTTCTATTTTAATATATCTAAATTTTTAATATTAGTTTTATATCTTTCATCATTTTTTAATCCTTCACTTTCGTAGCTATAATCAAAATTTACTGTAATCATATCATTGCTGTAATATCTATATTTTTTCTTATCAAATTTAATAAATTTCTTATGATTTTCTTGTAAATATATAGTTAATAAGCTATAATCCATACTACCTTTATATTTACTAAATATTCTCTTTTCTTCCTCATATAATTTATCTATGTCTTTTTTAATTGTTTTATCTACTATATATCCTCCATCTATAACATCTTTAGCTTGTACATTTAAAATCATTACATTTCTATTTCTCATATAACATAAACACCCCTTTTGATTTTTTATGATTTGTTAGAATTACTAGCTACCCTTTTAAAAGGATAAACTCTAGTGAGTCAATTTAGTTAAATCATTAAGCAATTTATTATCTTCTTCAAAACAGAAAACAACAAAATCTTTAATATTCCTATTTGGCTCTGTATAAATTAATTGATGCCCCATACTTATTAGTTCTAAAGCAATTTCGCGTTTAAATATTTTTTTAATTGTCATATTAACACCTCCATTTATAATTGAATTTTAGAAATAAGAAATTAATGAATAAGAAAAAGCAATATCACATAAACGAATTTAAAAAGAGAAAAATTATTTTTCGGTTTTTAAATCGTAAAGTCGTAGATTTATATGTTTTTATTTGTAGATTTATATGTATATATTATTAGAATTATATGTATATACGTCCGATTTCAGGGCATTTTTTCCTTAAAATCGGAAAACATTTTTAACTTTTTAAGGAATTTTTGGCTCAAAATCATACAAACAGGTATTATTTTAAGGGATTTTTGGCTCAAAATCATACAAAACACAAGCTAGTCATACCAACGGTTACATGGTTTTTCAGTTGATTTTTACCCAAAATTTACTTTTACTACATTCTCATTTTCTATTGTTTCTTTTACTGTTAGAGGTATATTAGTAATTCCATTTTCATGTTCACATTTCGTTTCAATCTGTTTATATAATTCAAAATCTTTCTTATCTAAAGCTTTCTTATATTCGTTTAAATAATTTTGAAAATAATGGGTAAAGTAATCTGCATCTGTTAAGTAAATGTGTTTATGACTTGCTGCTATATCATCGAAATGTGCTGAGTTGTAGTTTTTTTGTTTTTTATCACTTTTATCAATTTTAATTATATGCTGATATATGTATTCCACTCTCTCAAAAAGTGATATGTAATATATGTAGTTCTTTCTTTTATTTCCAATAAATTTTCCATCCTTATCATACAATGATGTCATTTCTGTTTTATCTGAAGTATATACTTTGATAATCCCTAAATTGTTTTTTGCCAATTTATCTATGTACTTTCCAACTTGTGATTTTTTTCTTCCTATGCTTTCCCCTATCTGTTCTAATGTTGGAAATGAATAATGTTCCAAAAATAATTTATAGTATATGTTTCCCATCGCATCTTGACTAGGTTTTGTCTGCCAATACCTATATCTAACACATAATACTGTAAATACTGCCCATTCTTCTGATGAAACATTATTGAGTACAGTTTCTATAAAACCAATGGGTAGAGCTCTATAACCTGTCCATTTACCATTTTTAAATGGATAATGCTCATTGTTGTTATAAACAATAAATATTTGAATTGGTGTGTTTACGTTCATTCCTTTAACTTTATTTAATTTTAGAATTCCTTCTTGATTAAATTTAACTAAATATTTTTTTATGTTATCTGTTGTTATCTTCTTATTTATTTTTAGATAAATTGTGTTTATTGTTGTTTCCAAAAACATTGTTTGATTACTTTTAGCCTGACACATTAAGTTCCACAATAAATACCACCCATCTATTCCGTAGATATCCGCTATATGCTTTCCATTGATTGATTGAAATCTTAGCTGTATAAATTGTGTATAATCAATTCCTTTCCCATTTTTAGTTAATTCTTTGTTTTTATACATATTCGTTTTAGTTGATTTACCTGTCCATTCTTCTGTTAAATCTTTAAAATCCTTATCTTTTACATTCACATAAACACCTTCCTTTTGATATTTTTGATTTTTTTACTATTGTTTTTAAATATTCTTTTCATCTTTTAAAATAATAGTTTTTATGTCCTCTGCTGTAATCTTTTTCAAATCATTTATGTTATTGTTTATCGTTATTAATTGCTTTTTATTATTATAATATTGTGGATTACAATTTTGCTTACGATTATATAAATGTGGTATTTTATCTGATGTTACATTGCAACCAATCTCCCAAGTTCTATTTATATTATGTATTTTTCTATAATTATTACAATGATCTAGCATAACATCTTCCCAACTATATTCTAGAAGTTTATTAAACCCAACTTTTCTAGCACTAAATTTAAATTTATTTGTTATAGTTATCAATTTTTTAACTTCACCTTTATTAAAACTATCTTTATTGCTAAATTCTTTTAACTTTTCAATTTTTATATTATAGTCATTAAGTTTTTCTATTATATAATTATCTAATTCTTCAAATGTCATGAAATTATCTATGTTTTTAAATTCTTCTGTTGTTTCAAATTTATAAGCACATTCATGACCACTTCTCCCAAAAACCCAGTTTAATAAAATTAGAAATATTGGACTAGCATCTTGAGTTTTATCTTTTAAATTCGGAAAAATATTTTCATACCTTTCTTCTATAAAGGCATGTACTAATTCGTGTCTTATAACTTCTCTTAATTCTTCATAACATTGTTTTCTATAATATTTCATAGGCATCTTATGACATCCCCATAATATAGGTTTTTTAATTTCTATTAAATGTGTATAATTATATTTATCTTTTTCTACTTTTGTGTACATTCCTTCTATGCGATAATCATCAAATATTTTTTCTCTTATTTCTATTGGAACTAATAAAAATTTTCTTCTCTTATAAAGAAAACACCTCTTCCTTAAAAATTCTAATTCTTCCCTTAAAGCTTTATTTAATAATTCCTGTCTTAATTTCTTAGATGTTCTTTTGATATATTTCATACTCAATCCCCCATTTTAATTATTTTATACTCACCATATCTATATTTAACTAATTTGTTTTTGGATTTTAAAACTTAAACCTTTTTCTAGCTCATGTTGTGGTACTGGAATGCTTTTTTCTCCATTACTATAAATTTTATGATCTCCACTTTGTCTTACTTCCTCAAATCCATAGTCCTTTATTAATCTATCCATTTTCTTATAGTCAAATATTTTTTTAACATTACTTTTATTATCTTTGTTTTTTGTTTCTATTTTCTCAATTTCATAAGCTTTATCATGTAGAATGTTTTCTACCCTATTTATTTCATCATTTATAAGTTTTTTATATGGATTCATAATTTCATCCGTAACAGTATTTAAAATAAAAGTTATTCTTCCTATTGTCTGATAAGTCCTACAATCCATCTTGTTAGCTAATTTTTGTAAATTAGCATAATAAGTTGTTGCTATCAATATTTTTATTTCGTCAATTATACTTTTACTTTCTCCCATAGTGCTTTCAATTAAGTCTTTTGTAAATCCTTTAGAATTATCCCTACTCAAGTATTTCCCAAATTCATTTACTATATATGAAAATTCATATATTAATTCATTACATTTTTTAATTGTAAAATTTTGACTTTTACATACTTTTTCAATCTCTTGCCTTATATTTTGTATTTTAAATAAATTTTCTCTAGCAATCTTATCAACAAAATTACTTATTTTATCATTACCTTCATCAAACCAATAATCTTCTAATTCTTCTTGTAATTTCGTAAATTCCCTGTTCAATTTAATTTCTAATGGTTTCATATTTATATCCCCCTTAAAATTTTATATACTCCTAATTATACAAAAGGGGAATAACTCCCCTAATGTTCTTTATTTATGTTTTATTCTTCTTCCCATCCACATTTTTCACAATGCCAACTACATTCTTCCATAACTCCTGCATTGTTTGGAAATTCATTTATAGCTATACTTCCACAATCAGGACAAATTTTCCCATACTTTTTTGCATACTCATAATTCTCTTTTTCTATTAATTTATCTCGTTCTTGGTCTGTTATAAAATCCTCTTTTGTAATATTACCTGCTTGTTCAATTTGCTGCTTAATATTTTCCATAGTTGTTGTATTATCTACCGTATAAACCACAATAGCATCTCCATAATATATTTCCTTAGTAGAATCATTGGAAGTATCATATATACTTCCATCTTGTCTTATACAAACCGCTATATCTTCCCTATGTTCATCTATTAATTTTTTCCCTAAACTTATTAATTCCTCATATTTTTCTTTATTTATCATTTTTACATTCCTCCATTATTTTAATATTTTTATTTATAGTTAATTTTAAAAAGGTATTTCTTCTTTACTTGCTTGTCCATACTCTTTTATTTCTGAATCTCCTAATTCTTTTCTTAGCTGCTCAAATTTTTCTGTAATTTCTCCACCATTTTTAACCTTATCCATTTCTTTTCTAAATTCTTCTCTTAGTTTTTCAATATTCATAAAATCATCATCCTCTAATCTTAATAAAATCTTTGTTTTATTAATTAAATTTAGTCAAATCTATTGAACTTAATAAATGTATCTGATATAATACCAGTAGACATAAAAACTTAGCTTAATATGCATTAAGCTAAACTTTTCAGACATTATTTGGTAAAACAAATGGTAACACAACAAAAATAAAGTAATAACACATAATAAAATACAAAGAATGTGCTAGGGAACAAATTAGGCGGACTTGTCCCCTTTGCAAATATTTAATTTTAAAGCTGTATATTTAATATTAACACTTTTTGCATATAACCTCAATCTGGAAATTCGGTTATATTTTAGTGTATTTTGTTAAAACAATTCAATAAATGTATTTATATAACTACTTCCTAATATTGGAGTGGTTTATTTGTGTTTATTTCATTTTCTGCATGATTGGAATAATATTTATATCAAGAGTGTTCTTTTAAAACACTCTATTCATTATGTTTTTTTACGCAATAATTTAAATGTTTGTCAAATTCATAGCATTGAAAAATCATTTCTAAATGTCTTACAAATGGTCTTATATCAAATCCTTCCTCAATTTCAAATGATAATACTACTGCATTAAGAATTTCCAACAAGAAGTCTGATTCTACTTTTTTACTTTCTAAGATAGCTGTTATATAATCAAATACACTTATTATTTTTCTATTTTCTTCAACATATTCTTCAATATCATCTATTTCATTATTATAATTAAAGTTAATCATTTTATAAATTATTTCCAAAAGTTCTTGTCTTTTGATTTCTATATTTAATAAAATAATCTCTTTTTCAATAGATTTTTCATAAACTTCTTCTTCAATTTCAAGTTTCCCCTCTTCAGCAGTATCAAAAACTCTAGTAACTTTTTTAGGAGGGTTTTCATTCTTCAATTTTATTATTTTAATCTTTAATTCATCACTTTTTTTAATTTCCATATTAAAATAATCAATAGGAATTTTAAACTTTTCATTTAAATGACTTAAATATTTTTTAGGTATTTTTCTACTACCTTTAAACCACTGGTTTATGTTTTGTTTCTTTATACCTAATTCCTCAGCCAGTTCCTGTTGCGTAAGATTATATAAACTTAAAATATATTCCAATCCTATCAAATAAAACACATCCTTTGTTTAATTGTTAAGCTTATATTTTATATAATACGCTATTTTTGTTTTACTGTCAAGCAAATCGAGGAAATTTTATACAGAGGTTTCCAAAATATCTAAAATATTTATTAATATGTTTTAAGAATTGATTCTCTGCAAATATTGTTTTAAGTAGTAATTTCTTTCTTCTTCTAATTCTTTATCATCAAATGGATAACTTTTTACTATTCTTATTAATTCTTGTATATCCTTATCCCTTTTATTTTTATGATCTGCTAAATTAATAACCCTACACATATCTTCACCTTCTAATATCAATTGTTCATTTGAATTTATATAATGTAAGTTAATAGCTCCAGAGAACCAATCTTCTTTCCAGTCTAATAATCCAAACTTGCTAATCTTCAAGCTATAACCCTCTATAAATTCTTCTAATTCTCCTACAACTGCATCTCCTACAACTATTATACTGTCTTCTGTTTCCAGCACTTCATGCTTGTTCATTGTAACAATATCATTATTAATTAAAGATATTCCATCAGATTTTAAAAATTTAGTTAGGTGTCCTAATTTATCCTCTCTTTTGTTTTCTATTTCTTCTAATGTAGTTTTTATCATTCTTTATCCCTCCTATTTGTAAAATCAATTATTTTTTTAATCTACTACCCTATATTTTTCGTCTTCTTTAGTTGCTGGTAATATTAACGTAGCATAATCTTCTGGATTTTTCCTTTCTATTAATTCCTTAATTTCTTGAAAGCTAAGAATACCAGTCTTCCATTCCATAAACATCCCACCCTTTTATTAACTTTTAATGTTTTTAATTTACTAAAAGTAAATAAGATTGTAATATATAAGGACTATAAAATTAGTCCTTGTAAAACTTTTTTACTTCTATAACATCTTTATTGATCTTCCATAGTGGACTTCTAAAATCCTCATGTATAAGAATGTTTTCTTTTTCTAATTTCTTTAACCACTTGGATACTGTTGCTTTAGATGTATTAAAATATTCCATTATATTATCTAGTTTTAATACCATCCATCCTCCAAGTACAGAATTAGGATATTGTTGAGGTATTATGTAATTTAAAAATCCTGCCTCACTTTTATTTATATCATGTTCATTTAACCATCCTGCATCTAATAAAACTGATTTTTTATCTTTGCTGAATTCAATTACATATATACCTTTCATTTTAAAACAACCCCTTCTGTTTTTCCTTACAAATATATTGTATCATAAAATTAAATCAAATTCAATATTTTTATATTATATTTCTTAAAAGTATTTTCAATTTATAAAATTTTGCTTATATATTATATTTAAAAGACTAGGAAATTAATTCTAGTCTTCTTTAATTAATCTATCAATAAAAAAGTTTTCTTTCAAATATTGCAAATTTATTATTTCAAACGTCATTTCATTTGTTGTTCTATGCTGAATCATAGTTATAATCCATCGTGTAGGTTTATCTTCTATTAAAATTGATGTATTAAATATTTTATCAAATGTTTCTAATATTTGTTTCTTTATAAAGCTATTTAGCAAATAATTATAATTATATGCAATCTTACAATTATTCACATTATCATTAAGTTCTTTTTTTATAATTTTGAAAATATCATTTAAAATTATTAACTCAAGTTCATTTTTAAAATTAATTTTTATTCCCATAATACACCTCATATGTTCTATATAATTATTATATAATTTTATTTCACCTTAACTAATACAAATCATAAAGCATTTTCTATTAACATAAATTGCTCTGGTACTATTTTTTTATACCAAAATCTTAAAATATTTATTTTTTATTATATTAAGGACTTGACTAATTCAAAACAATTTAATAAGGAATCGCGAGTATTTTAAAGTTATTTTACTTTTTTGATCGTATATGATAATATACTATATTATTAAATGTAATTCAATAAAATTATAAAAAAATGGAGGAATTTATAATGCTAACAAAAGAAAATGTCGATTTATTAATAACTTGTTTTATAAATGCTGCAAATTTAAAAGCTTCAAACTTCAAAATTAATAATGATTTTGAAATAGGTACACAAGGAGTATTAGATTGGGATGCTATAGATTTACTAAGTTGTGCCTTTGAAGATAAAAGTTTTATTGGTAAAGATGATATATTTGTTAAAATAGGATTAGAAGAAAATAGTTCTGAGTTCTTTAATACTCTAAAAACGCTAGAAACATTATATTTAAAAGATGAAGATAATAAAATAAAAATAATTGAAAAAGTGTCTTTAGAATCTTATAAAAATTTTGATGCTATCTTATATATAAATATAGAAACATATAACTATTTTAAAAAGAATAATATATTTGAAATAGTGTTAAAAGAATTAAATAGATTAATTAGCAAAGAAATAGAACAGCAAATGAAATTTTTAGATATGTTTGAGAAATATGATTTTAAATTTGACTAATTTAATAAATTATCTAAAAGAGGTACTGTTAAGAGGGAATAACTCCCTCAACCTCTTTTTAAATAAAATCTGTAAACAAAGTTTTTATTTTTATTTTTCATGATATTTATTTTTAACTATCGGATAATCAAAAATTTTAATATTACTATCTATAAACCCTCTTCTCCTTGCCCCTATTAAAGTTTCATACATGTTATCCCTACCTACTGGATTATCTGTATGTAAATAAATTTGATTGGCTTTTAATCCATTTTCACAAATATACTTTACCAAATCATAACCTGTAGATAATAAATTTCCTTCAGCATCTTCCCCTAAATCATGGTCTAAGGATAAAATATCAACATGAAAATTTTCTAAATAATATATTGCCTTTTCTACTGTTCTTGCAATTATGAATTCCTTAGGGCAATCTCTTAAATCATCTACGTAAAGATTTATTTTCTTATTCATATATAATCCCCCTAAATTTTTATAATTATAATTTTATTATTTTTTCAAATAACAATGTATGTTTAGCATTTATTTCAATATCCTCATTCAAATGACCAAAATACCAATGTTTAAAATCAACATTTTCTTCCATTATTTCAAAATATTTATTTAAATCTTCCTCAGGTTTAGGCTGAAATCCAAATATTTCAGTTATCTTTTTTAACACTAAACTCGAACAAGTATGAGTTACTATATAATCTACTTTATTATTGTGTTTTTTAAGATTATCTAATCCTTCCCTCATTTCGTTATAATCAGGAATTTCTTCTTTCCACCATGTAATATGTTCTCGTCTATTCTCTTTATCAGTAGATGTTGCTCCACCCATAGTCCAAAATTTTAGTCCATTAATATTAAATACCTGTCCCCTCATAAGATGATATATACTATTATTGATTTTATGGACTTTACCACCATGCCATTCTTCTACAGGGAATTGATATAATAAATCAAAATTTTCATGATTTCCATCTAAGAATAGAGTAGTCCAAGGCTTATTAGATAACAACTCTCTCCAATATAATTCTTGTTTAGAGTTATTCCAAATAGCACCGAAATCTCCGCAAATAATAACATAATCATCCTTGGTTAAATTTTTATAATTCACAAAATTTAGTTTTTCTATATCTCTAGGGATATGGGTATCTCCAGTAACAAATATCATAATGTCCTCCTAGGATTTATAAATACTCTTTCTTTATATATTTTAATATAACTTTTCTTAGCTTTAAATACTATTATATTAAATATAGTTAGTTCCTTAGTTTTAGTTATTCCTATAGCAACTATGTCAGAGCTTACATAGCTATACTGTCTTATATAATACGACAGTATTAATACATACAAATAAAAACAGTAATCTCTTGCAAATATTTTATAATTAACATACATTTTTAGCAAAATTAATACATAAATACTTGTAACAAATTACTGTTATTGATTAATAAATTGATTATTAATAATTTAAGACATGACAAATACACTTAATATATTCATATTTTTAAAAATTTCTGATATAATAGAATTAAGTGATATATGTACAAAATATTTAATTGTCTGCACTTGCGAGAGCCACCAACTCTTTCAGGTGCTTTTACTTTATCTAATTTTTATTCCTGTTTAATTAAACACTCAGATAAATTACCCTTTTCGCCCAGCAACAAATCCTCTAGTTTATTAAAATCATAGTTTCTCTGGTCAAAATCATTAAATTTATCTTTTTTAATATAATTATTATTTTTGTGATTAGTATTCTTAGTATTATTGCTCTGTGTAGTTTTATTCTCTTTAGAGCGATTATCTCGGCTTTTCACCTTATCTTTGATGTTTTGTATTGTTTGTTGTACTTTCTTCTGTAATAATGTATATACGTTCGAAGTTGAACCACGCCTTCTCTTAGCAATATATCCTAATTGAACTAATTCTTTAATATACCTATTTACGCTTCTACATGACCTCCCTAAGCTTACCGCAATGTAACGAATGCTTGGATATACTTCTGTTTTGTTACCATAAGCAAGATGCTGAAGCAGCATATAGCAACGATAAGCACCGTCAGAAAGTTTTAAATTCGTAATATCGAAATTGGAGGTAATTGTATAGTTAGTCATTAATATTTACCTCCTCTTTTCATATTTGCTAGAGGGGAAAATTGTTGATAATTTTTTCTTATATCTGCATCTGTTAAGTCTAAATACGCTTGCTCTGTAACTTTAACAGATGAATGCCCTAAAACTTGAGATAGAATATAAATCGACCCGCCTGACATTAAAAATCTTTTGGCAAAATTATTTCTCAATTGATGAGGATGAATATCTTTTAAACCTGCTCTATTCGCATAATCCTTTAATTTTCTTTCAAATGTTCTAATTAACACAGGAGTCCCTTTTGTAGTACAAAATAAATAATCTGATTCTACATATCTATCTTTATATTGAAGCCATCTGCGAAGTTCCTTTTGCATAACTTGACTAAAATAAACATATCTATCCCTTTTTCCTTTTGTATCCACTGCAGGTAATAGTATGCTCCTATAATTCATATCTATATTTTCTACTTTTATTTCTAGACATTCTCCTATTCTCATGCCTGTATCCAATAGCATCATTATGCATAGATGGTCACGTCTTTCGTGGAATTTTGTTGTATCTATATGTCTTAATAACTCTGCGAACTGACTATCTGTAATAAATTCTTTTGCTTTTCTTTGATTTTTAAATTGTTTAATGTTTTTTACTACATCTTTTTTTATATAGCTTTGTTCTAATAAAAAATTAAAAAACACTTTAATATTTCTAATATAATTATTTATTGTTGTTATAGAAACTTTTTTCCCATAATCTTTACGCATTTCTGGTGTATTAGTTTTTAAAGTTTCTTTATCTCCAACTATTGTGTATTTACCTCTATTTTTTGTATAATTTATATATTCTCTTATCATTTTTTCTGTAACTTTTTTAACATCTCCAATACCTTTTTCTTCCTCTAAATATTTAGTAAACAATCTTAGAGTTTGCTCATAACTCATCATTGTTTTTTTAGATAAATTTTTTGATTCACAATAAATCATAAATTCATCAATTTTTAAATTGATTTTTCGCAT

Protein sequences of DBSCAN-SWA_2

>NC_017297|1966595:2055534|1981209_1981794_-|WP_014519279.1|DBSCAN-SWA
MNLYERDYEKPSTKELEVIREQDEFNKIGIVSPEHVDPINKYSKEIRNFVYHYRTKFPNNVIWSRELNHEESKKESEAFKKVLDNSKSENDIQTYIKSNKKWFIPASIIKEYNFGHKENYLFPEMMLGSKYKVDYVICGRNSDGYHLLLIEFENANTPFINQDGNCESKSVNSGYGQIKNWKNWMDDNRQLFFK
>NC_017297|1966595:2055534|2004397_2005213_-|WP_012099844.1|DBSCAN-SWA
MNLKKIKESADFVKNNISIMPEIGVILGSGLGDLAEEIENKEIIKYSNIPNMPASTIKGHKGQFVVGTLKGKKVIMMQGRVHYYEGNKMSDVVLPVYIMKELGVKNIIVTNAAGGVNEIYNPGDLMIIKDHINFAFSNPLIGSNDEEIGPRFPDMSEAYNKSLIVLAEKEAEKLGFSLQKGVYAMMTGPSYETPAEIKMLRMLGADAVGMSTVPEVIAANHCGIKVLGISCITNMAAGILEQPLNHQEVIETSNKVRSKFISLLKSILEVM
>NC_017297|1966595:2055534|2037353_2037551_-|WP_012099883.1|DBSCAN-SWA
MDNFTNTFNIISGVCSIISLFIGIFVANKVTKIYNSNKIGDIKDIEQNSEGSNSPNIISGRDTHK
>NC_017297|1966595:2055534|1987870_1989766_-|WP_012099833.1|DBSCAN-SWA
MEKINSYKELKSYYENYKDLLKSRHTTHEEETAVENKKCERLILVCGGTGCKSADSDKIVESLKEEINKLGLQEEVKVSITGCFGFCEKGPIVKINPDNVFYVKVTPEDAKEIAEKHLLKGEVVERLLYEEPTLKEKVKRQDEMSFYKKQKRIALRNCGLINPEDIKECIGSEGYLALGKVLSEMTPDELIKLITDSGLRGRGGGGFSTGKKWSFGKMYDSDVKYIICNADEGDPGAFMDRSILEGDPHSIIEAMAIAGYAIGASEGRIYIRAEYPLAVNRLKIAMDQAKEYGLLGENILGTGFNFNIEIKYGAGAFVCGEETALIHSIEGERGEPTYKPPFPAEAGLWNKPTVVNNVETLANIPAIINKGADWYKSIGTEKSNGTKVFALAGKINNVGLVEVPMGTTLREIIYDIGGGIKNGKKFKAVQTGGPSGGCIPASLLDIPIDYESLTSIGSMMGSGGMIVMDEDNCMVDIAKFYLEFTVDESCGKCTPCRIGNKRLLETLIKITNGKGSEEDLNKLDELSHIIKDTSLCGLGQTAPNPVLSTMRYFMDEYEAHVNEKRCPSGTCKNLLHYEITDKCIGCTKCARGCPVSCIIGKVKEKHFINQEKCIKCGNCYSACPVGAIIKK
>NC_017297|1966595:2055534|1992190_1993069_-|WP_012099836.1|DBSCAN-SWA
MDTKTRILGGLFGVACGDALGITLENMDKEEIHNYGYLKEIVGGGVFDLKPGCTTDDTLMVLCVAKGILNNPEDPQDSIGNEFMKVYQDLMKYGGTTVKCTIEKFLECRDWYEASLHSSEVLSWQAAGNGALKRSLPVALYYKDYDEIIKITKEQSQLTHRSKIGERACLLYNTLIYYYIKGYDKNEALKLALKEFDEFYEITNINKYSLNSSLFAVDSLMCAIWSIMNTTTAEEAICEAVNLGGDAGSIGAITGGLAGVYYGYNALPKRWTDIIDKKQELLDIALKLSENG
>NC_017297|1966595:2055534|2014511_2015099_-|WP_012099851.1|DBSCAN-SWA
MKKNFKLIIGGLIIFIAGYFIGDATAIGRVNKQIGQSVDKQVSSTIEKAEEEKKDVKFGEQSPVGNLSIKILEAKENGAISNESGKSTPSGKFIVIKLDIKNNGEEATGYEPHEFKLNDGKKTYEVDDNSFEALGHLNSQESIFRENKNFIGSYDKINAGINKNTFLVFDIPKDVKIDNLKLITEHNKGIQFNLK
>NC_017297|1966595:2055534|2026124_2026727_-|WP_014519284.1|tail|DBSCAN-SWA
MAEQVVPVVGLEKLYAAKIIKDDNTGVTFDTPIYLEGIKELSIKPKITTDDFYAENKLWLSESTLANVDVEADITDLNTANEVFLLGHKLAIEGGIIYSDDDKAPDVALLYKANKGNGKARYGILYKGTFSISDEQYKGKEGKSNFRAKKLKATFAPLHFNGRWKYKVDEEEGMTDEKFFKEVIIPTEKVETTEKAILDK
>NC_017297|1966595:2055534|2037580_2037826_-|WP_012099884.1|DBSCAN-SWA
MEKVVDVKKRYSRELEDIDYILRNLENGRYYENTKAKMDGYLATNVSDIRKKVDDLINKIEYNKDSIDEQLMKELAKVQNR
>NC_017297|1966595:2055534|2045233_2046370_-|WP_012099895.1|DBSCAN-SWA
MNVKDKDFKDLTEEWTGKSTKTNMYKNKELTKNGKGIDYTQFIQLRFQSINGKHIADIYGIDGWYLLWNLMCQAKSNQTMFLETTINTIYLKINKKITTDNIKKYLVKFNQEGILKLNKVKGMNVNTPIQIFIVYNNNEHYPFKNGKWTGYRALPIGFIETVLNNVSSEEWAVFTVLCVRYRYWQTKPSQDAMGNIYYKLFLEHYSFPTLEQIGESIGRKKSQVGKYIDKLAKNNLGIIKVYTSDKTEMTSLYDKDGKFIGNKRKNYIYYISLFERVEYIYQHIIKIDKSDKKQKNYNSAHFDDIAASHKHIYLTDADYFTHYFQNYLNEYKKALDKKDFELYKQIETKCEHENGITNIPLTVKETIENENVVKVNFG
>NC_017297|1966595:2055534|2031776_2033534_-|WP_012099877.1|terminase|DBSCAN-SWA
MTIKEELIRYCNNCLKDVFVSKFETYISCEKHKWACQRFLNDIEKLENDKDYIYYWDEEEAQKIVKWFTYLRHSKGELAGQPIILTIWQKFFICQIYGWRRNDNERRRFKKSFIECARKQAKSQMESGIALYELACGSTRNDEIYEICCAGIKRKQSKVVFEEAKLMLKGSPLSTKFKCTRDYIMHIKTGSTMIALSKEDGTKNDGGNMALFILDEYHQHPTDDFYTMASYGQATKEPLLMIITTAGVDLNSPCYTQEYKYCSEILNPNIDVENDTYFIDILELDKKDDIHNKRNWWKANPLRMTYKAGQEKIQEEYEIAKQIPEKMPSFMTKCLDIWVQAKENSYMDMAKWKACEIKKIPYDLNNRVCFIGGDMSSKIDLTSLAFIIPIMDNGVKKYVIFSHSFIPSREKLMERTLKDKVPYDAWERIKDEYGKSKYITITNTPIVDQNVVIKYAIDFCKRYNWEIDTWCFDPANATKIMLDISDMGYDVTELFQSHNKLNESTVALREEVYMGNVIYLPNPVLNFAMSNAVIKSNNGLIKIDKDATKKKIDPVDALICGFKMAWLHEEKPNLNELIKKGEWIL
>NC_017297|1966595:2055534|2034727_2036521_-|WP_012099880.1|DBSCAN-SWA
MKLSKLYADNDTIFEPIYFNLGINIILAEVRNPSNLRKSSHDLGKSLLAKLIDYCLLKEIKKGHFIKNNYDIFEEMIFFLEISLDDNSYFTIKRPVKKGQKIMIKQHIEPHQNYNELEDRDWDFIGNIGKGKEYVNKLLSFDVLANRNYRSCLGYFLRNDESYSDLFKLSSFGGPDKNWKPALLELLGFKSKYIIEKYDIDTQISKNNEDIKKLTKANEDKIVEKEKLKTLICIKENDLENKSNLYNNFNFVTSDIKKPKKLVEEIDIELKNLINENYYLLKQIKNAKESIIDYNVNLDELETFYNEIGLYFENQLKKEYTELIIFNNELTKERNDILREIIKEGQEKYDINNKRIEELNLERSKYLEYLNYSNTMDKYKNLQNEIVDLKAKILNLKDKLENFDDASKIDLSNQQLEVDRTNIVFNMNKEIFGKENSCMNNIKKHFSYIINTTLGDLGIITLFPNKQSNINFKAEIIDSETNYKGNKGDGTTYKKLMCAAFDLAILATYYKSKYFHFVYHDGIFDGLDDRQKNNFYKIIEEYTKKYSIQHIFTVIQDELPTSIKKNDEISKLKDNKTIIKVLHDDGNNGRLFNMNPF
>NC_017297|1966595:2055534|2019088_2019910_-|WP_012099861.1|DBSCAN-SWA
MIKSFPFNAVYDANGVPDRAYLAEDFAGYFAKFIGTGVYPNPATGLQVVAVDGDMRIRIKKGYGYILGRDFENTDDYIFKLDPADGVLSRIDRVVLRLDYLDRKIKPILKKGNYGSSPIAPALQRNSDAYEIALADVYVKNGVISIIQSNITDLRLNKEFCGIVHGVIQQADTTEIFRQFQAWFNEQKNIHEGDFEKWVNEFKIATGKKFTDWVDDLKNSLDPSEDIAARLQMQISENKLQLADMATLKDRNTNVKYKLVVINGEPFLEVVGV
>NC_017297|1966595:2055534|2054541_2055534_-|WP_012099911.1|integrase|DBSCAN-SWA
MRKINLKIDEFMIYCESKNLSKKTMMSYEQTLRLFTKYLEEEKGIGDVKKVTEKMIREYINYTKNRGKYTIVGDKETLKTNTPEMRKDYGKKVSITTINNYIRNIKVFFNFLLEQSYIKKDVVKNIKQFKNQRKAKEFITDSQFAELLRHIDTTKFHERRDHLCIMMLLDTGMRIGECLEIKVENIDMNYRSILLPAVDTKGKRDRYVYFSQVMQKELRRWLQYKDRYVESDYLFCTTKGTPVLIRTFERKLKDYANRAGLKDIHPHQLRNNFAKRFLMSGGSIYILSQVLGHSSVKVTEQAYLDLTDADIRKNYQQFSPLANMKRGGKY
>NC_017297|1966595:2055534|2017433_2017649_-|WP_012099857.1|DBSCAN-SWA
MILYDLLKNLIDNNYYEKEDMNNKLNVFYTFNQIDMEQYSELMAKVNPAAKEDAGKQELNVEDIKEKVVTQ
>NC_017297|1966595:2055534|2040141_2040588_-|WP_012099891.1|DBSCAN-SWA
MDNNKMYEAIVEVNTKGSLQEQAKKLYDEEKLYKKLIDTYNKEMQEIDDDELLTDLYLMRKKYKIRLDHTKNEMCYLNKRIIDTLDVIEKYVDVDMFCKLFEIEEYDEEDDYYGNILGSTSKIGYVCRTGLIYNEKLAKEIIEEDRTM
>NC_017297|1966595:2055534|2025479_2025659_-|WP_012099866.1|DBSCAN-SWA
MHLHYSKEEFWNSTHAEIYKMWQNHIKFNGWEVKNNNEENNTKSDINYKKVNIEDIAFL
>NC_017297|1966595:2055534|2027878_2028172_-|WP_012099872.1|head,tail|DBSCAN-SWA
MIVTLEEIKQYLRIESDCIEEDSFLELLEKSAEQYIKNTTGKLFDDRNDLAKLACLIFICDRYENRGSADLTIKTQNALSYILAQLSYCYVGDKNES
>NC_017297|1966595:2055534|2048235_2048655_-|WP_012099898.1|DBSCAN-SWA
MINKEKYEELISLGKKLIDEHREDIAVCIRQDGSIYDTSNDSTKEIYYGDAIVVYTVDNTTTMENIKQQIEQAGNITKEDFITDQERDKLIEKENYEYAKKYGKICPDCGSIAINEFPNNAGVMEECSWHCEKCGWEEE
>NC_017297|1966595:2055534|1989777_1990257_-|WP_012099834.1|DBSCAN-SWA
MCSNELVNIKFKELEEYINNISNKKGSLIEVLHKAQHIFGYLPNEVQEFVAKKLDIPVSKVYGVITFYSYFTTEPKGENVINVCMGTACFVKGAGDVLSEFEKKLNIKVGETTKDGKFTLQVLRCVGACGLAPVVTINDKVYGHFTKNEVNKVLEEYGA
>NC_017297|1966595:2055534|2038821_2039010_-|WP_012099888.1|DBSCAN-SWA
MEDVVKDNILINGRIGELEYNIFEKDIDNLIKKYGSAFVTRELIEKTCKGMGLEQVVTELNN
>NC_017297|1966595:2055534|1984199_1985756_-|WP_012099831.1|DBSCAN-SWA
MSILTVKDISHGFGDRAIFEEVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLMPDEGKIQWAKDVRIGYMDQHLNLTKGKTIREVLREAFDYLFNLEKEMNDLYMKMGEVSQEEMEKMLNRTATIQDMLDHNDFYIIDAKIEEIARGLGIADIGLDKDVSDLSGGQRTKILLAKLLLENPDILLLDEPTNYLDEDHIDWLKNYLKNYENAFILISHDIPFLNEVINLIYHVENKRLTRYVGDYNEFIRIYEENKKRLEAAYERQQAEISKLEDFIAKNKARVSTVGMARSRQKKLDKIDKIELTKEKPKPEFNFKQARASGKVIFETKDLVIGYDSPLTKPLNIKMERGQKVALVGANGLGKTTLLKSLLGAIKPLEGDVTLGDYQYIGYFEQEERESNYNTCIEEVWKEFPVFTQYEIRSALAKCGLTTKQLESKIVVLSGGEAAKVRLCKILNRETNILILDEPTNHLDVEAKEELKRALKEYKGSILLVCHEKEFYEDIVTETWNCESWTLKII
>NC_017297|1966595:2055534|1974900_1975950_-|WP_012099824.1|DBSCAN-SWA
MKAKLILENGVKFKGNAFGCLKESVGEVVFNTGMTGYQEILTDPSYYGQIVTMTYPLIGNYGINLEDMESKSPKVRGFIVREKCSFSSNFRSEVELEDYLKQNNVIGLEGIDTRTLTKILRSNGTMKGIITLEDIEYEEVKEKLKDFSNKDAVEKVTVKEKYEVSGKGKHVAIMDFGIKQNIVRSFLNRGCNVTVFPANTKAEEILKVNPDLIFLSNGPGDPEDLTEVIENIKVLIGKKPIVGICLGHQLLALSLGGKTAELKFGHRGCNHPVKDLKENKVHITSQNHGYFVDVLPKDMEVTHISVNDGTIEGMKHKNLSIFSVQFHPEACPGSKDSDYIFDEFMKYAL
>NC_017297|1966595:2055534|2038183_2038396_-|WP_012099886.1|DBSCAN-SWA
MAGIFEEWHNASLLYFIKENKKVTIEQIKEEFPVNEEVVNLNNLVEDDLKQLLGMGKIKFEEGYYSVIEH
>NC_017297|1966595:2055534|2039010_2039265_-|WP_012099889.1|DBSCAN-SWA
MEERNEIALINRGKISWLYYHDVFEKRIDLINRHGQDLFAFIFENNETLHELLLEFDEHTDLKKYNNCFKHVALAIKKKKMEEV
>NC_017297|1966595:2055534|1995837_1996350_+|WP_012099838.1|DBSCAN-SWA
MLFFIISIFIIFILILIMPFKITVIYSDKDFNIYIYNFQWKKGEDIKKQNYINKKINVKKDKKKQKALKVTLEKCSFKPKANISTFLNYDLEDAAYSAIIYGVLQSLVPYIYRYLFKIFKLKNFNYNITPLFKNKNFIEFKFKGIFYISLVKIIYIYISFKINYKNLKRA
>NC_017297|1966595:2055534|2005250_2006126_-|WP_012099845.1|DBSCAN-SWA
MKNIIENYIKDLQKKNLSKNTLEAYRRDVEKFSEFVRNREEKILSVDTVTIMAFVQYLQREGRATSSIVRNIVSIRNFYKYLIKKNMVSEDPTLGYEIPKIERTIPKILSVEEVDKLLNSPNSSKKGLRDKAMLELMYATGVKITELLNLNIYDINLKFNYIKCRGSKKRERIIPIGSYAIKCLKNYLEVRPAINVYNLDYLFLNLKGTQMTRQGFWKIIKFYAKEASIDKEIDSYTLRHSFAVHLLQNGADIKSVQELLGHKDLAATQIYSSISKKSKIAEVYKNAHPRA
>NC_017297|1966595:2055534|2026794_2027151_-|WP_012099869.1|DBSCAN-SWA
MNIKQYILNVLNNKEIIDLLPDKRVYFLHAVNPDKKLYLEYEIVNEYGVEYSEGNEDYTTYIVQLDIFSTGDYTELENVVKKIMIHNGFNRDMAADLYEKETGLHHCAMRFNVSLPMD
>NC_017297|1966595:2055534|2047402_2048155_-|WP_012099897.1|DBSCAN-SWA
MKPLEIKLNREFTKLQEELEDYWFDEGNDKISNFVDKIARENLFKIQNIRQEIEKVCKSQNFTIKKCNELIYEFSYIVNEFGKYLSRDNSKGFTKDLIESTMGESKSIIDEIKILIATTYYANLQKLANKMDCRTYQTIGRITFILNTVTDEIMNPYKKLINDEINRVENILHDKAYEIEKIETKNKDNKSNVKKIFDYKKMDRLIKDYGFEEVRQSGDHKIYSNGEKSIPVPQHELEKGLSFKIQKQIS
>NC_017297|1966595:2055534|2006177_2006405_-|WP_003359007.1|DBSCAN-SWA
MFIEYKKAIVTLIKCFLILLFFGSLLPRALDSVLYNFFMKNKVYENSTLVFKNIDLKIKIIYNYILVFNNFLRGF
>NC_017297|1966595:2055534|2033534_2034020_-|WP_012099878.1|terminase|DBSCAN-SWA
MARPKKMLAIQEGHLEKKQQEEKKLQEQIIQTGMEQLEKPPKWLRDSLAKKEWKRLVEQFKTLSVISNLDLNNLGAYCNAYSSYIEATKELKGQPLTIEYTNKGGATNVIENPLIKIQLKYSDEMKKYSSLLGLTIDSRLKIATLKLTETKKDIVDEFGDI
>NC_017297|1966595:2055534|2017225_2017393_-|WP_012099856.1|DBSCAN-SWA
MRLLKGIKHILLGIAIILIGASFIISTDSSMGGYGEVIVLIIGLTQCIRGVKMDD
>NC_017297|1966595:2055534|1976466_1976634_+|WP_003493683.1|DBSCAN-SWA
MDMLELLIKGVFVVYIINLILKHNLFISNIKIKVRFLGLDIEVDSKEKKHPSSKD
>NC_017297|1966595:2055534|2036507_2036759_-|WP_012099881.1|DBSCAN-SWA
MKIRPNKHTDISKSLLKNTIYLIDILLEQDFIQFNELYLKYKMRNGNASFKNFILAIELLFCLDRIKYNKKNDLIRLCNYEVK
>NC_017297|1966595:2055534|2051951_2052437_+|WP_012099906.1|DBSCAN-SWA
MLTKENVDLLITCFINAANLKASNFKINNDFEIGTQGVLDWDAIDLLSCAFEDKSFIGKDDIFVKIGLEENSSEFFNTLKTLETLYLKDEDNKIKIIEKVSLESYKNFDAILYINIETYNYFKKNNIFEIVLKELNRLISKEIEQQMKFLDMFEKYDFKFD
>NC_017297|1966595:2055534|2021077_2021947_-|WP_012099863.1|tail|DBSCAN-SWA
MNKKEKFIFENEKGQQIEFSIWSPFFLENIDGISGLKNIIYSNKGMGQDGSTCVGNTLDDRNIVIQGAITENKELNREKLLSIINPKLKSRLIYIDGNIKKYVECIVETAPIIPKENNPKFQISLLCHNPYWKDYIDSKVNVALWKGDFHFPLVIPQGKGITMGHREPSLIVNVLNNGQVKTGMIIEFFARGTLKNPSLFNVNTREFIKINKGMVAGEKFIINTNYSKKKILQELNGVTTDILNYLDIVGGGDTFLQLDVGDNLFRYNADNNLDNLEVNIYFSPQYLGV
>NC_017297|1966595:2055534|2002452_2002701_-|WP_003402834.1|DBSCAN-SWA
MFSIMAIKISPRNEIAPNVQEILTRNGCIIKTRLGLHEATNDSCSKCGLILLELLNNKKEDIENLSKDLTSLDGVSVKLLEI
>NC_017297|1966595:2055534|1994517_1995654_-|WP_012099837.1|DBSCAN-SWA
MKKTLKNKFILIISLIFIVTLIPTKVYGKEESQKNKPPYINARCAIAIDKDTGIVLFEKSANEIVPIASTTKIMTTLVALKYGDLDRKIEISENADKIRGSVVGYRKGEKITLRELLYGLMLRSGNDAAIAIAEGIAGSVEDFSKLMNEYASEIGLLNSHFITPHGLDKDEHYSTAYDLALATATAKKYELFNKIVSSKDVKKEEYNFTRDYHNINKILWKIPEADGVKTGYTGKAGKCLVTSSKINGNDIIIVVLNCTPRWNETTKIHNYVKNNYDFKKICTKGDILDQAVFEEGSVNIIADKDIIIPFKNGADYSIKINKPKELNWKVKKGEDFGSLSILNGNELIYTKKLKAGNNLSKGGIKNWFLNKKKCISDK
>NC_017297|1966595:2055534|2006395_2007049_-|WP_012099846.1|DBSCAN-SWA
MENKFLGNINRHVQENFWLYIISLLCICTGIVLGIYSVKYMGSFEKGDLLSYVESFSKSISSNGIDSKSILFEAIKNNITIIVAIWFLGLTMIGIPVILIIDVIKGFTIGFTTSFIVNGLGMKGIWMSLLGVLPQNLIYIPCIIFASVLSMEFSIQILRDKNNRGFQNGIWVRATSYSFSFAFVVVIMFIGFLMESYITPNMIKLVVARAGVCMLCL
>NC_017297|1966595:2055534|2038480_2038792_-|WP_012099887.1|DBSCAN-SWA
MLFKNFTDNELKEIKMACKELQQTVKRIRGEKGNKESKEKAIEKQKREDIDLKELLDEAQKIYNVNNIEFQYLLKMYIDNIEDNRKNICEKCDEVISECRKYR
>NC_017297|1966595:2055534|2007255_2007792_-|WP_003362492.1|DBSCAN-SWA
MNFYEKTLEEQEIYKGKIINVVKQKVKLPNGKESFREIVKHPGAVAILAYKDKDTVLLIKQFRKAIDKDIFEIPAGKIEKGEEIESSALRELEEETGYKAKNMEYLGKIVTSPGFSDEYIYIYKALNLYKGKEGMEDEDEFIDLMEISIDKLKEYIKNGEVIDGKTISAVMMDTLSKK
>NC_017297|1966595:2055534|1968562_1969435_-|WP_012099821.1|DBSCAN-SWA
MNNSFCPLIERKDTTSKILCREAMESINHKKTKKINAIWLEVTGCSGNIISLLNAENPGLIYILRNIVNLTFNNSLMGAEGEFAYEQFLNTLDTEFILLVDGAVSTRENGYYNIIANYKGKPVTALEAIKMAGEKARYVVTVGTCSSYGGISAARPNPSGSKSVEAVINKEVIKLPGCPCHPDWVVGTLAHLVTYGKPELDNKGRPILFYGITIHDSCTRRGFFDKRIFAKKFGEEGCMFKLGCRGPVTKTDCPRRKWNGYVNWPIGDNTNCIGCAQERFPDGMEPFVRY
>NC_017297|1966595:2055534|2017650_2018010_-|WP_012099858.1|DBSCAN-SWA
MFGYRIIFDKQNGTVINNYINTEGYIPISHRPKEIDFLDLPYGYNENNFKEAIEYHIDISKDKDATNLKDLIVIAKYREHTETEEEKLKNELLKTQAEVVDLKYKEVLNNKNLNEKEGK
>NC_017297|1966595:2055534|2030276_2031527_-|WP_014519285.1|portal|DBSCAN-SWA
MGIFNKMWAIKNTTTETVNQSDWFTSLIKSRTTTSGEKVTKESALTISGVYACTDIIASSISKLPIHIYQKNKDGSNRVDNDVSYLLEKRPNLYMTPSTFKHTLTVKLLLDGNTYVWVERRRGKAINLWILNNVQVLQDPTTGEIIYKATLNNKSHTFFNDEIIHIKSLSTDGILGKSKIDILRETIGNMQSSRKLLGNYFKNGTTTSGVITYPSNLNTDAKTEIRKQWEENNSGYDNAGKVAVLDLGLEYKEINSLKFTDQQFLESTKFTLEEIARVFKVPLHMINSLDRSTFNNIEQQSLDFYMNTILPLLLQIEEEFNYKLFSSTQREKYFIKFNMEGALRGDSATRSTYYEKMINLGVYSINEVRKLENMNSIGIQGDTHRVDLNHVDIKVANDYQLAKANSKKKGGEIDNE
>NC_017297|1966595:2055534|2015227_2015986_-|WP_012099852.1|DBSCAN-SWA
MKIGIDCGHTLSGADYGAVGIKAESNLTREVGTKVISKLQALGHTVIKCYKDTCSSLQDSLSYRTNMANNNNVDLYVSIHFNAFNGSAYGTEVLTYGGKSFTEASRVLNNICTLGYTNRGIKDGSNLYVLKHTKAKAMLIECCFCDNRNDMSRYNAENMANAIVKGLVEKTTNNSIPSQPSTNNGWVNLDGKTGTICTPSGVNVREKKSTSSRILGTLPNGAKVRLYRKEGDWIHIYYPSHGGYIYGKYVKY
>NC_017297|1966595:2055534|2050854_2051184_-|WP_012099904.1|DBSCAN-SWA
MKGIYVIEFSKDKKSVLLDAGWLNEHDINKSEAGFLNYIIPQQYPNSVLGGWMVLKLDNIMEYFNTSKATVSKWLKKLEKENILIHEDFRSPLWKINKDVIEVKKFYKD
>NC_017297|1966595:2055534|2001252_2002311_-|WP_012099842.1|DBSCAN-SWA
MKKIGQVLLGIIILVILIIAGYILFMTVTDYKPEDKIQLSIEGQTEDRLNLKDSFSIVTFNIGYGGMDDKQDFFMDGGKGSRSSSKEKTMENMRGITSFLKKDNSSFIFLQEVDTNSTRSFRIDQYDYLKNSLKAYSSSMALNYKTPWVPVPILKPHGTVNAGLVNLSKYKINSATRYQYPGKESWPRQLAELDRCFLESRVSLENDRELVLINSHLSAYDKGGKIRKQQLSFLKNYIIKEYKKGNYIIVGGDWNHLIPGTDPLMFKTTEKWPDWLQKIPNDFKPEGFKWVADKNVPTTRTDATPYKKGENFTAVIDGFLVSDNIEATSVKAYPMEFKNTDHNPVKMEFKLK
>NC_017297|1966595:2055534|2039339_2039894_-|WP_012099890.1|DBSCAN-SWA
MGRRLIRIKTINVCGVYGIYYIENNNKIYIYVGSSKECNDSYSRHKHFLEKDKYKNTNKRQMQEIFNKEDLYFTILEECNEEDRLEIETKYINLYKDTIVNKEQHGKSRRSKPTIEETERRRKSNIGTRNPNCKYDLDTILEIKQMIEMGLSNIEISKKTGINRNYISQIRTGQKWSCINILPI
>NC_017297|1966595:2055534|2027520_2027889_-|WP_012099871.1|head|DBSCAN-SWA
MKVKTGEMRHRITIQKYTTTQNENGFDIEEWDDYKTVWASMNNLWGKEFYAAKATNSENTIEFIVRYSKDLKNINTKEYRIKTIKDKNATKEKNKYRYFDITFIDNIQYKNKWLKIKAIEVI
>NC_017297|1966595:2055534|1982967_1984074_+|WP_012099830.1|DBSCAN-SWA
MVKIINDELKYSTLYDHYKETISYLKTDLTKRDKITWILLGLLVLYFLVEFKPIDSINVANKLIKSKTGSSIIVNYDILVTGMLLLILFSTMKYFQMCLYIERQYNYIYDLENKLNAISDEKLITREGYSYLQEYPLLSALIHRIYNLFLPLSIIISMFIKVHRLFKSQISITIIFNIAIGIGCISIVCLYLLFAYRHVKFIKFINECVKKLFVLLHLYEKNKGEHNMAKKKVCISFDYENDKNYKNLLAAWDVNTNFEFSFNDLTPTEINSNDYSRVKAVITQKISSATYLLVIVGEHANDEHPRKSEIGDRNWINWEINKAKELGKKLVAVKINKSYESPTALLNSGASWAMSFTKDSIIKALDEA
>NC_017297|1966595:2055534|2029540_2030284_-|WP_012099874.1|protease|DBSCAN-SWA
MSKFYEFKNRTDNNIDIYVYGEIIGGSEKWDESNVTFNDFKDNLEGLTGNETINMYINSVGGSVTTTQGIIAMLQRAKEKGVTINATIDGIGASCASFLPLVADNVYAYKSSLLMVHHPYTLCIGNVDELQKQIDLLNKIENSVMMPLYLNKAKEGITKDKIKNLVDKETWLNAKEMSEIFNIEILEDDKDLVACVKDKSILNKYTNVPKQLKNKLLEDKKTTVKTENVKDKEELELAKARLRLLYL
>NC_017297|1966595:2055534|2046415_2047357_-|WP_012099896.1|DBSCAN-SWA
MKYIKRTSKKLRQELLNKALREELEFLRKRCFLYKRRKFLLVPIEIREKIFDDYRIEGMYTKVEKDKYNYTHLIEIKKPILWGCHKMPMKYYRKQCYEELREVIRHELVHAFIEERYENIFPNLKDKTQDASPIFLILLNWVFGRSGHECAYKFETTEEFKNIDNFMTFEELDNYIIEKLNDYNIKIEKLKEFSNKDSFNKGEVKKLITITNKFKFSARKVGFNKLLEYSWEDVMLDHCNNYRKIHNINRTWEIGCNVTSDKIPHLYNRKQNCNPQYYNNKKQLITINNNINDLKKITAEDIKTIILKDEKNI
>NC_017297|1966595:2055534|2027161_2027521_-|WP_012099870.1|DBSCAN-SWA
MADGIEIEGMEEFTEMLENMTIDEADETKVVRKGIEVVAKQVESNTPVLTGKLKKIKKSVKKEGFATVGTVKLGAWWDLFQEFGTSQQKYHVGFFDRAVKGSENEAIEVVAKELLDKAK
>NC_017297|1966595:2055534|2054041_2054542_-|WP_012099910.1|DBSCAN-SWA
MTNYTITSNFDITNLKLSDGAYRCYMLLQHLAYGNKTEVYPSIRYIAVSLGRSCRSVNRYIKELVQLGYIAKRRRGSTSNVYTLLQKKVQQTIQNIKDKVKSRDNRSKENKTTQSNNTKNTNHKNNNYIKKDKFNDFDQRNYDFNKLEDLLLGEKGNLSECLIKQE
>NC_017297|1966595:2055534|2018630_2019092_-|WP_012099860.1|DBSCAN-SWA
MSLQIGDLIPLQGLTKEDKKKLVDIVNKAEANQSIIKTNIINSLNNKLKTALKTDSSWIDIQNAIISSNCANYTKGILKGNEYNYSLNTGFKARVISLTKGDDVLIWCYPKAEFDHYNNIAIWRYDTYVSLQRRYSNQDALQLDGYSWEAWGI
>NC_017297|1966595:2055534|1998213_1998804_-|WP_012099839.1|DBSCAN-SWA
MSELYSLCTEENWREAIKQCYKYNLLDINLNLLGLENILLDYSNIYVRILNVLYSIKGEHGQSIFIDNSFLDKDLRKPIDKYLQNKEIYSLSLSNAKDNYEIYKILSKTYSVERVLLAWNLKFRYKVYNYEKNIRVMNLAMNGQDIKKLGIKEGKEIGLILEYMKKYKINLGLLDEENFLIDNTGEIKNAIKYKNT
>NC_017297|1966595:2055534|2002807_2004112_-|WP_012099843.1|DBSCAN-SWA
MRMYDLILKKRNGGELSKEEIDYFILEYTNGNVPDYQASALLMAIYFQKMKRRETVDLTMAMVNSGDILDLSKIQGIKVDKHSTGGVGDTTTLVLAPMVAALGIPVAKMSGRGLGHTGGTIDKLESFKGFSVNMTEDKFINNVNNIKIAVGAQTADLAPADKKLYALRDVTATVDNISLIASSIMSKKIAAGANAIILDVKVGEGAFMKTPETAKELAEEMVNIGKSVGRDTVAILSDMDQPLGYAIGNALEVKEAIDTLKGKGPKDLLELCLTLGSNMVILSQKANTIEEARKMLLSTIEKGLAIEKLKEFIRSQGGDGTLVDNTEKLPKAEYIIPVICDRNGYINKIHAQNIGIIASELGAGRVTKDSIIDLAVGIVLNKKRSDKVKKGDIIAYIHANDKIKGEKAEKDILNNYVIEEELKEELPLIYDTVK
>NC_017297|1966595:2055534|2019916_2021074_-|WP_012099862.1|DBSCAN-SWA
MELYIFNRDLELKGILDTFTSLRWIRKFNISGEFELHCPLGFKTLELLKRENVIFKKNDVEAGYIETRQLKISEDGQEYLEIKGKFLTNYLDRRISWDRVNFDGKAEVLMRNLVLENAINPTNINRKIQNLTLGSLKGFNKDIKYQNSFGNVLQQLENISNTSNLGYRNLLDIKNRLIKFDVYKGVDRTINNGTIAPCIFSRDFENILEQQYMDSLNNYKNTTLIAGAGEGKDRKITSIENGKGLDRFEVYVDARDITDKEEKKKIVVDKDEEGNVTGEHEETEEVEIPWERYKPLLLQRGKEKLSECEEIQTFDSKINTNGNNVYKKDYDLGDIVTVVDKKWGVRIDTRITEIEEVYEEKGLEVNVTFGNNIPTIIDKIKQKVR
>NC_017297|1966595:2055534|2034167_2034635_-|WP_012099879.1|DBSCAN-SWA
MIDIALKKLCRCGKVIDYNKRMCDECKNKYDKSKKESYKEYKKNRKDNREQKFYSSKEWIPVRDMVRRKYNNICLYSYYVNKEIKYCNVMHHIIELKENWDKRLDIDNLIPLSDKVHKIVHRAYDRSAKDKKEMQELLRELKRKYEKEFGTNLKS
>NC_017297|1966595:2055534|1966595_1967054_-|WP_079991858.1|protease|DBSCAN-SWA
MSIAIKVIAIGNILMGDDGIAIKIAKNIEGFLKENYIDLIIGETDFEYCLSRIKKEDFLFILDAGYYGKKIGDITILPLDTYTSHKNGYTQHSYSFIDLVKLYYNEIKGYILAIEVSNIDYTLEISKELKVNMNKISDELISIIRKKGKYFK
>NC_017297|1966595:2055534|1980084_1980810_-|WP_012099827.1|DBSCAN-SWA
MRSFGLVEYKIYESDYFLEKINECINLIGCQYLFSAFVSACRSITFSLQSYMNGIEGFFDWYANKQEYSRKQKIAKKFVEMRNESQKVGVVYIGSRRMYKNDEGAMKSKFFFMGDHNYYDRGKLPQEKLLKNLFSNDRQDDLEEDVATQCERNFKLLLEVIKDYYTTFGHIIDPEKYYTIENIGKIGLEIEDFEESVGFPRGYTCAEGLTDEIRIALIRENEPKSEIYYIFNKYFEHGRYE
>NC_017297|1966595:2055534|1997492_1998239_-|WP_003402816.1|DBSCAN-SWA
MPLNIKIHNFDGPFDLLLHLIKKNKMEIYDVSIYEITNQYLQYLNQMEELDLEITSEFIVMAATLIEIKSKYLLPKVEEEKEEEENDPQKELLSKLLEYKKFKAAAEFFKNRQQISGTSFSKKPEIIEVKNKETTTDELLKDVTMLSLYNTYNDLISKYSNKMNENVEFKGEIQLDKYKIEDKIKYIGKKITSKEKWLFSDFIKECSCKMEIVVTFLAILELIKLKTIQVYQSNNFNDIYIERGVVCE
>NC_017297|1966595:2055534|2031570_2031753_-|WP_012099876.1|DBSCAN-SWA
MMLVTFIMKNIDDILILGGCSILTTAFFIYVSKFSGMIALSTILILIGLILSKLPKKDSN
>NC_017297|1966595:2055534|2025718_2026063_-|WP_012099867.1|DBSCAN-SWA
MLHKIRKQKIGDKEYSFRMVNKTIRKIDEKYGNYGDVILGLMEGKQFYTNTLKLISLSCIEKEWDIEELENTMTAEQYQEITVLAVNIYLDYMGLNEETEEERAEKKEVKKEKN
>NC_017297|1966595:2055534|1969702_1970404_+|WP_012099822.1|DBSCAN-SWA
MNLDGFKLKIIAMILMVLDHLPKAFNNTPIWFGWLGRLVAPIFFFFVAEGFFHTRSKSKYLIRLFGWGAIMFAGSSILNYALPGKEPLQNNIFLSLGLSVLLMCIIDYTRKSKNYKFGIPLAIIVSIVSLFTEASFDGVLMTLVLYFFREDKIKLSIGYILISLFEFIMVSGEGLTYLNLFVLNYQWLMIFALPLILMYNGERGLNNKFIKYMFYAFYPIHLWIITIISHFLK
>NC_017297|1966595:2055534|1986117_1987851_-|WP_012099832.1|DBSCAN-SWA
MSLVTLNINGKELKVEKGTTILDAAKLLNINIPTLCNFHLNDNRTENKPGSCRVCVVEVEGRKNLAPACCTPVGEGMIVKTNSIRAIKARRAIVELLLSDHPKDCLLCEKNTKCELQKLAADMGIREMKYQGDVSMYPIDISSYSIVRDMDKCILCRRCITMCNEVQTVGTLSAIGRGFETVVAPAFSEAIKNTNCTFCGQCVSVCPTGALTEVNNTSKVWDALSQKDKVVIVQTAPAIRAALGEEFGLEPGTAVTGKMVAALRQLGFSKVFDTDFAADLTIMEEASEFIHRLEHGGTLPMLTSCCPGWIKFFEHNFNDLMDIPSSCKSPQQMFGAIAKSYLAEKMKVDPKDIIVVSVMPCLAKKYEAKREEMKRNGIPDVDIVISTRELAKMIVEAGIDFNSLQEEEFDNPLGQSTGASVIFGTTGGVMEAALRTAYEWVTKGTLKDVEFIEVRGEDGIREATVNIKDTEVKVAIASGLGNARKLLNDIRNGKSKYHMIEIMACPSGCVDGGGQPYIYGDTNILKKRTEALYKEDSNKEIRKSHENPYIKKLYEEYLGKPYGEKAHELLHTKYRVR
>NC_017297|1966595:2055534|2018025_2018613_-|WP_012099859.1|DBSCAN-SWA
MLDNTAKIGEIITALENMQGLNQKADLKSALIAKGINALDTDGVANLIAKLNSANLVLNGKKFITGKIYVSEVRSYCGKPSDNPSSMNYITNRTFNKQISCPFEVGVFAVDLDEFTATSSSNKVHLNIAKDFLISGFPQYDISGYHSWRDYFHFYSSGTKIDGYTINLEWNNLTIPLYDISDRLRSSLNWIAIEK
>NC_017297|1966595:2055534|2052527_2052890_-|WP_012099907.1|DBSCAN-SWA
MNKKINLYVDDLRDCPKEFIIARTVEKAIYYLENFHVDILSLDHDLGEDAEGNLLSTGYDLVKYICENGLKANQIYLHTDNPVGRDNMYETLIGARRRGFIDSNIKIFDYPIVKNKYHEK
>NC_017297|1966595:2055534|2012517_2013096_-|WP_012099849.1|DBSCAN-SWA
MKFNGWNSFEDLARACGYTNSHKDSDNTSETSNNNATNESCNMGCYDIPNGFQSLNPQLFVAIGGILGDILAGSIPANVQAALGNWLLLVGQAIVTFNAQQIYFQQGPGRYFNPQNYNVDNPFCQTTSQNTTQNNSSSKNSKNSSKSKEKNSNSDYNKKSSSKNKIDKIEELELRINQLISEVERIKNEIEK
>NC_017297|1966595:2055534|2028256_2029489_-|WP_012099873.1|capsid|DBSCAN-SWA
MTKVQEIQAKIQEMKGEAKNLKTADDINAKIKEIEDLQAQLKIAEMEEADEKKSVENKIKEGKMKNLSEEKDVNNMGNKVIYNGNLFAKAIADATLKARNKKGFVFNEGEQRAISEHVGEDGGFTVPEDIKTEINKRLRDTTDISNLVNFEKVYTRSGQRTYEKRKKQTELTNLDEYGKIQEVDYRQLERISFKLHDCAGLKTIPNDLLEFAGEGLKNFIIEWLVDKVRFTKNIKVLYGTGGENEVQGIMTYKDIKVIDLSATATIKDFKKLINVELPSYYKTSATWVTNQDGYNFLDCLEDKQGNSYLRPDPKNDEVDKLLRKNVVELPNEVLETKDGKIPVILGDLKSLYTYYSDGEYQLLSTNIGGGSFESNTTKTRLIYKMDGGIVDKDAVIIAYIPTTVVEKATK
>NC_017297|1966595:2055534|2052915_2053596_-|WP_012099908.1|DBSCAN-SWA
MIFVTGDTHIPRDIEKLNFVNYKNLTKDDYVIICGDFGAIWNNSKQELYWRELLSNKPWTTLFLDGNHENFDLLYQFPVEEWHGGKVHKINNSIYHLMRGQVFNINGLKFWTMGGATSTDKENRREHITWWKEEIPDYNEMREGLDNLKKHNNKVDYIVTHTCSSLVLKKITEIFGFQPKPEEDLNKYFEIMEENVDFKHWYFGHLNEDIEINAKHTLLFEKIIKL
>NC_017297|1966595:2055534|2049326_2049992_-|WP_012099900.1|DBSCAN-SWA
MIGLEYILSLYNLTQQELAEELGIKKQNINQWFKGSRKIPKKYLSHLNEKFKIPIDYFNMEIKKSDELKIKIIKLKNENPPKKVTRVFDTAEEGKLEIEEEVYEKSIEKEIILLNIEIKRQELLEIIYKMINFNYNNEIDDIEEYVEENRKIISVFDYITAILESKKVESDFLLEILNAVVLSFEIEEGFDIRPFVRHLEMIFQCYEFDKHLNYCVKKHNE
>NC_017297|1966595:2055534|2037950_2038133_-|WP_012099885.1|DBSCAN-SWA
MEEKRICPKCTGTMLKGIHEDCKTVFEPMGSGKVVDIYKYVCLSCGFVEEYADIEKFNKE
>NC_017297|1966595:2055534|1990744_1991932_-|WP_012099835.1|DBSCAN-SWA
MASSLAIIILLGLIANKLFEKLKLPGLLGMLILGILIGPHGLDWLSKDILNASSDLRKIALIVILLRAGLGLNKEELKLVGKTALKLSCIPGIIEGLFIAIASVKLLGFSFVQGGLLGFIIAAVSPAVVVPQMLNLIDKGLGKAKGIPTLILAGASIDDVFAITIFSTFLGLYAGKNINIAIQILKIPVSIILGTLIGVLSAIIIIKIFKKYPIDNTKKILIILSISIILTLIEALLKGKLEIASLLGVMALGFVISDKIPSIGDKVSKGLNEIWVFAQILLFVLVGAEVNMVIAFKSGFLGIIIIALGLIGRSIGVLISLKGSNLNKEEKLFCIIAYIPKATVQAAMGAVPLANGVAAGDIILAIAVLSILTTAPLGAIAINLSGPRLLESNLS
>NC_017297|1966595:2055534|1971666_1974873_-|WP_012099823.1|DBSCAN-SWA
MPLNKDIKKVLVIGSGPIVIGQAAEFDYSGTQACEGLKEEGVEVVLINSNPATIMTDKKVADKVYLEPLTVEFVEKVIAKERPDSLLAGMGGQTGLNLAVELYDKGILKKYGVNVIGTSIESIKEGEDRELFRNVMSRINEPVIQSEIVTDMEDGKDFANKIGYPIIVRPAYTLGGTGGGIAESEEELDEILALGLQLSSIGQVLLEKSVKGWKEIEYEVMRDSRGNCITVCNMENIDPVGIHTGDSIVVAPSQTLSDKEYQMLRSASINILNSIGIKGGCNVQFALNPNSFEYAVIEINPRVSRSSALASKATGYPIAKVASKIALGYTLDEIKNAVTEKTYACFEPSLDYVVVKIPKWPFDKFQGADRVLGTKMMATGEIMAIGSNFEAAFLKGTRSLEIGKYSLEHKKFRELSIEELKTRVISPDDERIFALAEMLRRDYRMDKVAEITGIDKFFIKKFRWIVEEEQRLRLSKIDDLDKEWLYKLKKKGFSDKGIADMLKVSPEDIYRLRNIWRINPIYKMVDTCGGEFEALSPYYYSTYDVYDEVEVSKNKKVIVIGSGPIRIGQGIEFDYASVHCVKALKKLGIETIIVNNNPETVSTDFDVSDKLYFEPLTEEDVLNIVEKEKPDGVILQFGGQTAIKLANFLKEKNIPTLGTTADQIDMAEDREKFDELLEKLKIARPKGKGIWSVEDGLEEAKKLGFPVLVRPSYVLGGQGMEITHDEKELVYYLSNAFQKDKKNPILIDKYLMGREIEVDAISDGEDVLIPGIMEHLERAGVHSGDSITMYPTQNVSKDIKEKILEYTKKLALGIGIKGMINIQFIEFQGNLYVIEVNPRASRTVPYISKVSKVPIVDIATRVMLGEKLNDLGYGVGVYKEPELISVKVPVFSTQKLPRVEVCLGPEMKSTGEVLGVGKTLDEALYKGFIGANISIKKEKGTVLATINDHDKEEFLPIAKKLHSLGYKFIATSKTAELLKEEGIEVKQVRKLKEESPNIIDTIKNDEVDLVVNTPTKGNDSKRDGFHIRRAAIERNLGVITSLDTLKAIVDIKFKEIKDETLYIFDLSN
>NC_017297|1966595:2055534|1993310_1994405_+|WP_003405456.1|DBSCAN-SWA
MTKNKKIPFLEFIPIIVISFLLLKFINNIENIYSFIKSFLSILVPFIWAFGIAYMLNPLMKYFQNKFKLNRILSIILTYIIVIGLLTLFINTFVPKIIKNVGDLFAHSPDYINKTIQWFNENIKYSKAYDMLMENSQISNNIPNLINKISNLTNTFINTFLNTTIKFTSSLVKFVFGLIISIYLLLDKESLIENFKKFILALTGEKIYSKTLSFFKEVDLVFSKFIIGKAIDSLIIGLMCFAGLNIMKVPYAALIAFIVGITNMIPYFGPFIGMIPAFVITLFFNYIKAIWVLIFIIILQQFDGWYLGPKILGNQVGLSPIWIIFAITIGGGTFGVMGMFLSVPIAAIIKIYLDKYIEMKLNKK
>NC_017297|1966595:2055534|2053592_2053778_-|WP_012099909.1|DBSCAN-SWA
MYVLILSYYIRQYSYVSSDIVAIGITKTKELTIFNIIVFKAKKSYIKIYKERVFINPRRTL
>NC_017297|1966595:2055534|2016636_2016831_-|WP_012099855.1|DBSCAN-SWA
MQARKLMKDRELAAYLDINNSNLPFEYYENKYLKQGYTGNLLYRKILEASNRANKEVNKQLGII
>NC_017297|1966595:2055534|2021962_2025463_-|WP_012099864.1|tail|DBSCAN-SWA
MASNTEKRITAKMVLDSTGYNDKLKGLNAEMKKHQAELKFASQGIKSFGKDSEKLKSVQEALSKQVELHSKKVDIYSKAIEKTKTRLDDNIKVRDKLKKSLDDANKKYEQAVKVYGKESEQAKKAKEEVDRLKQEHEKASKAVETNAKQVQGYETNMNKANAQMVKTQGELKKVNGELEKSNNKWLKAGENLKKSSERLKSVGGGMEKAGEGILKFTAPLAAGGIASLKFATDFEDSIAKVSTISDESEVSISDLRKGILKLSNDTGIASTEIANNVYDAISAGQKTGDAVNFVSNSTKLAKAGFAEAGQSLDVLTTIMNAYKMKAEDVTKVSDYLITTQNEGKVTVGELSSVMGKVIPTAVATNTSLKQVTAGYALMTKNGIKAAESTTYMNGMLNEMSKTGSTADKSIKAVSGKSFPELMKSGKSVSDVLNMMNDHAKKNNLSLKDLFGNAEAGKAALVLSTNAGADFNEMLGKMEQSAGATDKAFAKVTNTTGERFKKSLNKIKNEAIRLGDAIAPMMDKLSELMSKLSDKLSGLSDEQLKNIAKWGAMAIATGSFLKVGGKAVSGIGSLVGGIGQATEWIGKLSGATKVAESVAGGASVATAGVTKGISAMGLATKAVTLLLNPWVLGIGAATIAGVALYKHLKKDATPSVDLFADKVSKSNTAMMNYSAASKGVETSNVKISKSTKQAVGAYMDLDKKASKSMLNLVANSNKFSKQAKDKVLKNFTDMSKKSSKISNEQKNAMITNFKKLVTDTGVLTKKNKDEIIKQYTAMVNGTKGLTKKQKDQTIKEFTDTLNKSTAITKQQSDNLQKIYKDMGDKIKIGLDKKKAEELQSQQDFFSKSNVLTTTEEAKILQTTTTSWENKKKTIDGLQNQINSIIQHAANNHRQITTEEAQTIDGLQKKMKENAVKTLSASEVEQKVIMERLKNYNGRITAEQASEVIKNAEKQRQGSVDKANQQYDQTVRNIIKMRDETKVITKDQADKMLKEAERQRKESIDKAENQKKEVVKKITSMNKDIGESVDTTSGNMLTTWDKLKSWWDGWKPKKHTFEWSMNKGNASGFNERWTGDRFYGGGLTTLHERGYELYDLPRSTRIYNHEASEELVIQTAENVATKVANSLLSGFKGTNGVNVTQHIYAPVPTPSEMARQSKNNLRELSLQW
>NC_017297|1966595:2055534|2051334_2051664_-|WP_012099905.1|DBSCAN-SWA
MGIKINFKNELELIILNDIFKIIKKELNDNVNNCKIAYNYNYLLNSFIKKQILETFDKIFNTSILIEDKPTRWIITMIQHRTTNEMTFEIINLQYLKENFFIDRLIKED
>NC_017297|1966595:2055534|2040638_2041316_-|WP_012099892.1|DBSCAN-SWA
MLRKFTNKELSEIEEIQYAKKVLNEEGAYSYQNEKYVYFYNNNKELIRIDNNLESKMENYYELNEFMKEIYEKTYKEYKSKKMEDDVMIMLEKVYKEIKRKKGLQTNTTLTEDMINATKLLKDSFKKINEECNITMGESKELESTLKKFNNDECGGGFIYFLHEQNNEEVLIQLDLVDYSSCIVCKVEEIEDFQFIKEEDGIYLKLHEKYEGIDHVWIDEMGVQM

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_079991858.1|1966595_1967054_-|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_012099821.1|1968562_1969435_-	hydrogenase small subunit	NA	NA	NA	NA
WP_012099822.1|1969702_1970404_+	conjugal transfer protein TraX	NA	NA	NA	NA
WP_012099823.1|1971666_1974873_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_012099824.1|1974900_1975950_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	5.2e-58	36.6
WP_003493683.1|1976466_1976634_+	hypothetical protein	NA	NA	NA	NA
WP_012099827.1|1980084_1980810_-	hypothetical protein	NA	NA	NA	NA
WP_014519279.1|1981209_1981794_-	DUF4263 domain-containing protein	NA	NA	NA	NA
WP_012099830.1|1982967_1984074_+	hypothetical protein	A0A2H4J496	uncultured_Caudovirales_phage	6.8e-16	38.3
WP_012099831.1|1984199_1985756_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	1.7e-52	29.7
WP_012099832.1|1986117_1987851_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_012099833.1|1987870_1989766_-	NADH-quinone oxidoreductase subunit NuoF	NA	NA	NA	NA
WP_012099834.1|1989777_1990257_-	NADH-quinone oxidoreductase subunit NuoE	NA	NA	NA	NA
WP_012099835.1|1990744_1991932_-	potassium transporter	NA	NA	NA	NA
WP_012099836.1|1992190_1993069_-	ADP-ribosylglycohydrolase family protein	G3M9X5	Bacillus_virus	5.2e-51	39.5
WP_003405456.1|1993310_1994405_+	AI-2E family transporter	NA	NA	NA	NA
WP_012099837.1|1994517_1995654_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	8.5e-22	30.8
WP_012099838.1|1995837_1996350_+	DUF2953 domain-containing protein	NA	NA	NA	NA
WP_003402816.1|1997492_1998239_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.0e-07	25.8
WP_012099839.1|1998213_1998804_-	hypothetical protein	NA	NA	NA	NA
WP_012099842.1|2001252_2002311_-	endonuclease	NA	NA	NA	NA
WP_003402834.1|2002452_2002701_-	hypothetical protein	NA	NA	NA	NA
WP_012099843.1|2002807_2004112_-	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	3.5e-128	56.1
WP_012099844.1|2004397_2005213_-	purine-nucleoside phosphorylase	Q5YFI9	Singapore_grouper_iridovirus	6.7e-61	41.9
WP_012099845.1|2005250_2006126_-	site-specific tyrosine recombinase XerD	A0A1B1IQT7	uncultured_Mediterranean_phage	3.0e-14	26.5
WP_003359007.1|2006177_2006405_-	hypothetical protein	NA	NA	NA	NA
WP_012099846.1|2006395_2007049_-	stage II sporulation protein M	NA	NA	NA	NA
WP_003362492.1|2007255_2007792_-	NUDIX hydrolase	NA	NA	NA	NA
2010013:2010030	attL	NA	NA	NA	NA
WP_012099849.1|2012517_2013096_-	hypothetical protein	NA	NA	NA	NA
WP_012099851.1|2014511_2015099_-	DUF4352 domain-containing protein	A0A0A7RUM7	Clostridium_phage	2.5e-09	32.8
WP_012099852.1|2015227_2015986_-	SH3 domain-containing protein	I1TJX3	Clostridium_phage	3.4e-51	58.7
WP_012099855.1|2016636_2016831_-	hypothetical protein	A0A0A7RU02	Clostridium_phage	2.3e-28	98.4
WP_012099856.1|2017225_2017393_-	hypothetical protein	NA	NA	NA	NA
WP_012099857.1|2017433_2017649_-	hypothetical protein	A0A2H4JGH3	uncultured_Caudovirales_phage	7.0e-10	69.6
WP_012099858.1|2017650_2018010_-	hypothetical protein	A0A2H4J342	uncultured_Caudovirales_phage	4.3e-20	54.3
WP_012099859.1|2018025_2018613_-	hypothetical protein	NA	NA	NA	NA
WP_012099860.1|2018630_2019092_-	hypothetical protein	NA	NA	NA	NA
WP_012099861.1|2019088_2019910_-	hypothetical protein	E2ELJ8	Clostridium_phage	5.7e-52	56.1
WP_012099862.1|2019916_2021074_-	hypothetical protein	A0A0C5AMZ5	Paenibacillus_phage	6.3e-65	36.4
WP_012099863.1|2021077_2021947_-|tail	phage tail family protein	E2ELJ6	Clostridium_phage	3.7e-49	42.7
WP_012099864.1|2021962_2025463_-|tail	phage tail tape measure protein	A0A0A7RVT5	Clostridium_phage	7.1e-67	51.5
WP_012099866.1|2025479_2025659_-	hypothetical protein	A0A0A7RUE3	Clostridium_phage	2.1e-20	76.3
WP_012099867.1|2025718_2026063_-	hypothetical protein	A0A0A7RUF5	Clostridium_phage	2.8e-37	69.7
WP_014519284.1|2026124_2026727_-|tail	tail protein	A0A0A7RUI3	Clostridium_phage	7.8e-75	71.1
WP_012099869.1|2026794_2027151_-	hypothetical protein	A0A0A7S158	Clostridium_phage	7.9e-51	83.6
WP_012099870.1|2027161_2027521_-	hypothetical protein	A0A0A7RUF1	Clostridium_phage	8.9e-34	60.5
WP_012099871.1|2027520_2027889_-|head	phage head closure protein	A0A0A7RUH8	Clostridium_phage	3.0e-37	66.7
WP_012099872.1|2027878_2028172_-|head,tail	phage gp6-like head-tail connector protein	A0A0A7RWM0	Clostridium_phage	1.9e-13	42.4
WP_012099873.1|2028256_2029489_-|capsid	phage major capsid protein	Q0SPK4	Clostridium_phage	3.1e-94	49.5
WP_012099874.1|2029540_2030284_-|protease	Clp protease ClpP	A0A0A7RUD3	Clostridium_phage	8.1e-98	75.9
WP_014519285.1|2030276_2031527_-|portal	phage portal protein	A0A0A7RUE7	Clostridium_phage	2.4e-187	79.9
WP_012099876.1|2031570_2031753_-	hypothetical protein	A0A0A7RUH2	Clostridium_phage	2.2e-12	70.4
WP_012099877.1|2031776_2033534_-|terminase	terminase large subunit	A6M948	Geobacillus_virus	3.1e-119	43.2
WP_012099878.1|2033534_2034020_-|terminase	phage terminase small subunit P27 family	A6M947	Geobacillus_virus	1.5e-20	41.4
WP_012099879.1|2034167_2034635_-	HNH endonuclease	Q0SPJ9	Clostridium_phage	1.7e-24	44.7
WP_012099880.1|2034727_2036521_-	DUF2326 domain-containing protein	NA	NA	NA	NA
WP_012099881.1|2036507_2036759_-	hypothetical protein	NA	NA	NA	NA
WP_012099883.1|2037353_2037551_-	hypothetical protein	NA	NA	NA	NA
WP_012099884.1|2037580_2037826_-	hypothetical protein	A0A2H4J8H2	uncultured_Caudovirales_phage	2.3e-09	45.7
WP_012099885.1|2037950_2038133_-	hypothetical protein	NA	NA	NA	NA
WP_012099886.1|2038183_2038396_-	hypothetical protein	NA	NA	NA	NA
WP_012099887.1|2038480_2038792_-	hypothetical protein	NA	NA	NA	NA
WP_012099888.1|2038821_2039010_-	hypothetical protein	NA	NA	NA	NA
WP_012099889.1|2039010_2039265_-	hypothetical protein	NA	NA	NA	NA
WP_012099890.1|2039339_2039894_-	nuclease	NA	NA	NA	NA
WP_012099891.1|2040141_2040588_-	hypothetical protein	NA	NA	NA	NA
WP_012099892.1|2040638_2041316_-	hypothetical protein	NA	NA	NA	NA
WP_012099895.1|2045233_2046370_-	hypothetical protein	NA	NA	NA	NA
WP_012099896.1|2046415_2047357_-	hypothetical protein	NA	NA	NA	NA
WP_012099897.1|2047402_2048155_-	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_012099898.1|2048235_2048655_-	hypothetical protein	NA	NA	NA	NA
WP_012099900.1|2049326_2049992_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012099904.1|2050854_2051184_-	hypothetical protein	NA	NA	NA	NA
WP_012099905.1|2051334_2051664_-	hypothetical protein	NA	NA	NA	NA
WP_012099906.1|2051951_2052437_+	hypothetical protein	NA	NA	NA	NA
WP_012099907.1|2052527_2052890_-	hypothetical protein	A0A109QIR8	Bacillus_phage	4.9e-32	61.9
WP_012099908.1|2052915_2053596_-	metallophosphoesterase	NA	NA	NA	NA
WP_012099909.1|2053592_2053778_-	hypothetical protein	NA	NA	NA	NA
WP_012099910.1|2054041_2054542_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012099911.1|2054541_2055534_-|integrase	tyrosine-type recombinase/integrase	Q4ZE80	Staphylococcus_phage	2.7e-08	22.0
2067214:2067231	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_017297|2528453:2588159|DBSCAN-SWA
ATTGGTATTTAAAGATAGACTAAAAGGACTAAGAGAAGATAGAGACCTAACTCAAGACCAAATAGCAGACGTTTTGAGCATAACACGTTCGGCTGTCGCCAACTATGAAAACGGCATCCGCGAGCCAGATATGGCTTTATTAGTAAAAATATCTGACTATTTTAATGTATCCCTAGACTATCTTTTGTGTAGAACAAATAAAATGGAACCATTTTATAAAAATAATAAAAAGAATAAGCTATGATTTAATATTACAATAAATAGTTAAGAAAATCACATATTTTTATTTTACAGTAATTATAGATTTTCGACATCTGTAATTACTATAAAATCACTTATTATAAATGATTTTACACATATAAAAGTATAAGGTAAATAGCATAAGCATTTACAGTGGTTTTTTTATAGTTATGTAAACTTTATTAAATATGCTTTTAAAATTAAGTAATTTAAATACAAGATGTGTAATTTCAGCCATACAGGAATTTTATAGTAAAACAAAAACTCTAAAGGTTAACCCTCTAGAGTTTTTTATATTATAAATAATATTATTTTACTGGCACTTCAAATTCTATAGTATTATAAGATTCACTACTAAATACTATTCTTACTTTACTTTCATCAGCTTTAGCCATGTTTTTATAGCTATAATCTACTTCTATTATTTGTTTTCTATGCTTTCTTCATATTCTTTTAATGTACTAATCATAGCAGATATAGCCTCTACACCTATATCTACTCCTTCAATGCCATCTATAATTTTCAGGCCATCTATAATAGAATTCGCTAACACAAACTTAACACGCTTAGTTTTAGCAAATTCTATTATCTTTTCTAATCCCTTATGGCTACGTGTTAATCTATTTATGTCTTTACAAAATATCGTGTCTCCCTCTTGTACAATATCAAATAATTTGTTTAATTCTACTCTGTTGGTATCATTGGCACTTCCAGTATCTTTATAAATATTTTCTTCTTCAACTCCATTGCTTTTTACCCATTCTATTTGGTTTTCCAAGCTCTTACTATTTAAATTTCCACTTCTACAATATCCATATAACATGATATTACCTCCATTTATTTTTTTATAATACAATTTTATCAAATTTAATTTATTTTTACCAATTTTATTACTATATTGTTTTTAGGATTAGATAAATAAAGAAATTTTTCTCCTTCTTTTACTTTATTTAAAGATACCCAAACAGGTTTTGCCTTATCTAAACAATACATATAATATCCGTTTTCTCTTCCATTGTCTTCTGCTGGTGCAACCGCATTGGCTACACCAACAAATCTAGTTGAAGCTCCTATTAGTAAGCCTGTTAATAAACTTATAACCACCTTTTTCATTTTTTTTAATCCCCCAATTCTTGTTTTAACAATTCTTCTCTTTCTTTTAATAGATCCATAAATTCTTCTATGTCCTCAAGCGTTGCTTTATTTCTTATAAAGCTTCTAGCACTACTACGACTCTTTAAATAGCTTGCGTATTCTCTGTTTTTTTTCTCCCAATTCTGGTTAGCTATTGTCTGTTTAGATTTTCCCATTTGAAAACCTCCTACATAACTATTTTAAATATCAAGCATACTAATAGAGCTATAGCAATAAACTTAATGGTTATCTTTAATATTAATTTAAATAATATTTTTAAATCTTTACTCATATTTACTAAGGTGGTATTATAAGAGTAAGGGAGGAGTTTTCCTCCCCTGTGTTCATAACAAATCATATAGCTGTTTCAGTAGCATTATTATGATTGTTATTTTTACTAGTAGCTTGATAACTATTCCCAGTAGCTTATCAAGCTTTTTTAATTTTTTTATCCATTTGACCACCTTTTTCCCTCACCTCCTTACAAATATAATTATACTACACGTAGTATGAGAAATCAATACCTTTTGTGTAATTTTTATATAATTTATGATAATTTCCCCAATAAAAAGAAGGTACTTCCATTACAGAAGTACCTTTAAAATTAATATCTTATATATTTCCCATAGACATAACCCCCATGTGGTGGATAATAAATATGTATCCAATCTCCTTCTTTTCTATATAATTGTACTTTTGCACCATTAGGTAAAGCTCCTAATATTTTAGAAGATGTATTTTTAGCTTCTCTTATATTTACACCGCTTGGTGTATTTATAGTACCTGTTTTACAATCTAAGTTAACCCATCCATTATCGCTAGTAGATGGCTTGCTTGGTGTTACATTTGAAGATGTGCCTAAAACACCATTTACTATTGATTTGGCGATTCCATTCATTCCATATTTATTAAGTATAGCTACATCATGAGAACTATCTATGAAGCATACTTCTATATAAATTGTTTTGGCTTTAGTTCTTTTAGTTAATGCCAAGGGTTGGTCTTTAATTCCTCTATTCCTAAATCCTAAATTATTTAATTGCTTTAATGCTCTATCTGCCTCTACTAAATACTTACCATTATAAGTATACACTTCTGATCCATAACCACCTACTGTAGTGTTAAAATGTATACAGATATTTAAATCTGCATTTACTGAATTACATAAAGCTACTTGTTTATTTAAACTTTCTTGCAATGTTGATGCATAATCTACTCTACATATGTTAGTGCTATGTCCTCTGCCTCTCAATTCTTTATCTATTTCTCCTACTAATTGCCTTGTTAATACTTCTTCTTTTAATCCATTTATTCCTCTAGTTCCTACATCTCCACCACTTAATGTGTGTCCTGGATTTAAATTAAATAACATAAAACATTCCTCCTAATTATTTTAATAATAAAAAAGAACAGGCATTAATCCTGCTCTTTACTTTCTTTTACCGCTTGTCTAGCTGAACTTTGTCCAAAATAAAACCCTATTATTAATGTAAATACACTCAAAAATTCTGTACTAGATAAGTTTCCTTTTGTACTTAAAATACAAAATACTATTGTAGTAAGTAATGCTATAATCTTTTTAATCTGTAGAAATTGCTCTAAAAATTTTATAATATTATTACTTTCTTTCATTTAAACACCCACCTTTCTATTTAAATAAATTGTGCTGAATTGCATAAAAAAAGAAAGCCACTAAAGAGCTTCCCATTAATGTACATAACCATTTTAATATGCTTGTTAGATTTCTAATATCTTTACATAAGTTTTTAATATCTGCCTTACTTTCTGCTAATGTTACTTCTATTTTATCAATTCTTTCTGAATGATTATTAATCCTAATATCATGTACATTTATTTTTTCTTCTATCCTTTTATGCTTTTCTTCGCAGACTTTTAATTCCACATTACACCTCCAAAATATAGTTAGAAAGGAGCTATATTAAATACTCCTTTTTCTTTATTAAAAATCATTTTAAAGTCATCTTTTATTTCTATAATATTAAACCCATCTTCAAGTTCATTTGAATTAGCTTTTTTATATTTTATAATTAATTTAGATCTATACTCTGAAACCAAGATTGCTCTTCTATTATTTATATTAATCTCAATTTCTCTTGGATTAAGTTCTACAATTAACCCTCCTATATTTTTAACTAGATCACCTATAAACATAATTATAATCATACATATTAATATATTATAAATTTTAGGATGATTTTTTATTATACCATCAAAAAACATTGGTGTATTTTTATTTGCTATTTCTTTTTCAATGCTTCTTTGTTTATATTTTACCCTAATTTGACATATTTTTAATATAAAAAGAATTATCAATAAAATTAGCATACTAGGAATTTTATGATATTTCACACTAACAGAACTTAACCAAAGTATACCTGATAAGCAAACTGATAATATTTTAATATCATTAGAAATCCATTTTGGAAATATATCTACTAAAACACTAAAAATTCCTTGTGTAGATAGTAAAACTAAAGTGGTAATAGTAAATAAAAATATAATTCTTCTTATAACAATGGATGAATTAATTTCTACAAATGCACTTGGAATATTATAATAAGATAAATACCCTACTTGAAACATATATGTAAAATAGTATAATAAAGCTGTAATTATTCCCACAAATATTAATTCAATATATTTATCCAATTTACTCATATAACAATCCCTCCCATGTAACTATAATTTATACTCACCACTTTATAATACCAAATTATAATTAATAATTCACTTCTTAAATTAAAAATAAGCAAAATAAAAAGACCTATATGGTCCCTACTTTGCCTTTATTAAGTTTTTGTTTACTTCATAATATTTATCTATTGCGTAGCTTCTTCTACACCTGTAACATCTGCTGTATTTTTAATTATATAATCTTCTACTGCTTTTCTATACTCCTCATTAGTTACATCATCTAATAAGAAAGGTCGTTGCCTTAAAGGATTTTCACCTTTATATATAATCCTTTCAGCTATTATTCTTACTACTATTTCATTAACCATATTATAATATACCTCCTGTTTCTTTATTTTCTTTTAATAATAATTGATTTTCTAATTCTTGCTTTTCTCTTTTAAGTTTCTCTTCATTGGTTTCTACACGCTCCATATATTGTGTTATAACAATTAAATCTTTTAAGTTGCTAGTGTTTTTATTTTTAAAAATATCTATATGATATTCTATTGCATTTTTAAAATTATTTTCATTATAACTATACGGTAAATCTATGAAATCTATTTCTTTTGGTCTTAAATCTATATTTGAAGTTGTAATTATTTCACCGAATGAATTATTTAAAATAACACCTGTATTTTTATCAAATATTAATCTTTTACCAAATTGCATTTTATCACCCCTTATTCTATTGCTATCCATTTAAAATTACTATGGATACAGGTTAAAAAAAAGTTTTTCTGAATAGCAAATCCATTATTAGTTGCAGTTATATCATCCGTAAAATCAGTTGTGAATTTGAAATTATTGCCTGAGCCAGCACCAGCACGTACTGAAAGCGTAGATCCTTTTAATTGGTCGGATGTGTATTGCCCTCCACATATGAAACCATCACTAGTGTATATCATGTTTATTGTAAAATCTACATAATTGGGGCTTCGATTTTCCCAACCAGATATTAATATAATACTTGGTTTAAAATCTAAATAAGATATTATAAAATTTTCTGTAAATTCAACTTCTTTAAGTTCTCCTTTAGCATACTTTTTGCCTGTATTTATATTAGCAACTTTATTTATTAAATTTAATAAAGATTCACTTCCATTTGACACTTGTTGTTTAGCAGTTAAATTAGTAGCAAAAGTATTTTTCAATGTTTGTATTTTATCCCTTTGTTGCTGGAAGGTATCAGTAGCCAATAATGGAGTTCCAACAACGCTGGATATTAAACTTTTACCATTATTGGCATTTGTAAAAAGCTCATTTATGGCTCCTGTGATTGTTTTATCTTTAGTTAATCTTTTATTATCTGTCGTAATATCAGCCAAATCCGACTTAATACTAGTTATATTTTCCTCGTTTTTACTTACCCTTTCACCTAAATCCACCATATTACTATTTATTATCTGTATATCTTTCTGTGTAGCCAGTATAACCGTTGGATCTACCTTTAAAGTTACGCTAGATGTATTGCTAATTTCTAAATTTGTTCTTATAACTAGATCTTTTGTACTTCCATCTTGAGCCTGTGGTTTATATGTTTCTGGATATTTGCCTATGGCTAGCATATTATTTTCATCATCAAAAACTCCAGCTTCACGTATCATAAACCCACCAACGGAACTTGGTATTATAACTTCTATAACTACCCAGTTAGGATTGTTTTCATCTACTCTAATAGAATTTATATTGACTTGCCATACTTCATTAACTAAACCCTCCTGTTCTTCTGTTGGATTATAATATTTTCCTTTACCATCTCCAACCTTAAGAGTTGTAAAATTAACTTTATTTCCTAATGCAGTTGCATTAGCTATTTTCGCTTTACCTATTTTGGTTAGTATTGTATAAAATTGTTCTGCCATTAATTAAGCCTCCTTTCTAGGGTATACTGTTATGTTTTCTACTCCTGTATTGCTACCCATAGCTATATTAACTTTACCTTTAGATGTTATATCTTTAGGCATCCATGGATAAACAGTTATTTCCTCGCCGCTTGTTATAGCACTAGCAAAATAAATATTAGTATTTATTTTTTGTCACCAAAGTAGAACTTAACATCATATTACATGGAATTATATATCTAAAGTTATCTATTATTTCATTAAACATACTCCAATCAAAAGTATTTATTTCTACTTTTAATACATATTCATCATTAAGTACTTCAACTTTATAGTTACCCTTGCCAAATAAGGCATTTAGTTTATATTCAAGTGCCCTATGAGTTATAGGCATCTTATCCATCTTTCTATTTTTAATTCTTAATTTTCTAAACTCCAATGTATCATTTAATAGGTCAGCTTTAATTTTAAATAACTTTTCTTGATGTTTTATACCATATTCTGTTGCAGTGTCTATAAAATTTTCTTTTAGGATTCTTTGCTGTCCTTTTTCTAATAGCTCAAGCTCTACATCTTCTGTAGAAGTAATTTGTTTAAAATCTTCTATATCAGCTATTGGTGGCGGTAAAAAATCAATTAATTTCTTTTTCACTTAATACCACCTCTTTCAATATTGGAACTTCTTCAGTTCCTAAAGTTAAATTTTCCTCTTTACCATTTATCTTAGTATTAAATAAATCTGCTACACCTTCTACATTCAAAACTCTAGCTTCAATCTGACTTATTCTAACTATTGTATTATCATCTTCATGCCATTGTTTTCTAAGTTGTTTCAGATATTCATTTATAATTTTTTTAATATCTTCTTGAACTTGGCCAATAGTAAGTCCTCTCTTTAAAAGTATGTTTGTTTCTATAGTTATCTCTATATCTTTAGCACCTAATACAGTAACAACATGACCTACTGGAGCAACACCAAAACCTTTGCCTTTATTTTGTACTGGATCTAAAATAGTTTGTACCTTATCTATTAATTCTGTTGTAGGAACACTATAATCACTATCCAAAAATACTATTTTTACAGTTCCACCACCATTCCATATAGGAAATACCTTTACGGTTCCAACACCTTCAATAGCCCTAGTATTAATTTTATAATCTGCTATATTACCTCCATAAGGTTTCTCATTTAAATGCTCTATATATCTATCATATAGACTCTCGTTACTTTCAACATCTTCTCCTGGCATAATAAGTTCTCCTAATGTAGCAATAGAAAGTTCTTCAATATATTCAATTGGTATTAATGGTCCTATTATAGAGTTTCCCTCTATACCTGTTGTTTCACATTGCATTTTATATAAACCAGTAGAAATTTTTTCTACTGCAATAAAATTAAAATCTTCTATAGAAAATCTACTATTCAAAGGAATGTCTATTAATTCATTTTCTTCGTTATAAAAGTATCCTTTTTTAATTGCATAAGTTGCTTTTTCTCTTTTAAGACCTTCTTCTGCTACCCTTAAATCTAAAAGTTCTTCTGGCATATCGGGGCTTGCAAAAGTACATTTTAAAAAAATAATCCATATCTGAATACATTTTAGCAACTTCTTGAGCTGCTGGCGCTAAAGCATTATAAATTATAGAACCTTCTCTTTTGTCTAAATCATTGGATATTTTATTCATCATTCTATCTAAAATCACTTCTTCGGTTTGATCTTCAAACAACTATTTCACCACACTTTCAGCAAATTCTCCATAAATAGAAAAGACGGTAAAACTTACTTCTACACCGTCTTTATCATAATTAAATATAAAATTATCAACATTATTAATCCTATCATCTTGGCTTAAAGCTTCTCTTATTCTTCTTTTAAACTCACTTTCTGCTATATCCTTTTGCCTACCTATAAGTCCATTAAGTTCACTCCCATAGTTCCAACTATAGATAAGATACTCATATCTTTCTGTGTTTAGAATTAAAGCTATAGCTTGTTTTAAGGCTTCTACATTATCTATAAATCCTACTATTCTATTATCTTTAATTTTATACGTTTTTGTTGGTTCGATTATTTGTTCCACTTCTATATCTTCATCAAGTATTGCACCTCGTGGTAATATACTAACCTCACTCACACCTACACCACCTTATCTAAAATGACATACTGTTGTCCACCTTGTACTCTCAAAAGTAGTACCTTATCCCCTTGTTTTAAACCTTCTCTAATTAATAACTTATCTAAAGATGTATTTAGGTTACTTTCACTAGAATTATTTATATAAGTATGAGTATGTTTTAAATCTATTTCATATTTAGTTAAGCTTTCAGGGACAATAAAAAAGTCCCTATCTAGCATAAGTTTCTGGTCCACTTTTATTTTTAATTCATCTGCATTTATAACTTCACCAAAAGTTATTTCTACAGGTTTGCAAGCTCCCACTGCTCCCATACTTGCTTTTTTTAATTGTATCTATCATTCCCATATCTACACCACCTTTAAATCAAAATCCATTACAAGTTGTCCTTTAGAAAATTTATGTGTAGCTTCTTCTATAAGGTAATACTGTTTTATTCCCTTTTCTTTTATATCTACATACACACCACTACCAGCTCTTAATTTTAAATCCGCTGCTATATCTGTGCTAATAACATCTTTTAATTTTAAAGTTTTAGTTTCTCTATTTTTAAGCTTTAATGCTGCATTAACCATCTCTTGAATCTGCGCCTTGTTCATTTTTTCATCTACTTTTTTGAAATACTGTAATCTTCCCCACCTAGCAATGTTTCGGCTATCTTGTGCTATATAAACATCTCTACCCTTAGTATCTTTATTATCTCTTACTATTTTAACTCTATTATAAGTATCACTATCTATACTATTTTTCCAATCATAATCTCCTAAGTTACTATCATCACTAATAACTACAGGTTGCTTCATGTTATTTATATTTTTTAAGTTTAAATATCCAAAATCATCATATAATGTATAAGTTCTTTTATTGTTCATTAGGGTTTTTTCTAAAGAACTATATATTATATCTAGTAATTTTTTATCATCTTCTAATAACTGTGGTATAACATACCCTGTATCTTCTATAGTCCCTACTCTCAACCCTATATCTTTTGCAATTTGTATTAATATTTGACTTGCTTTTTTATTTTTAAATACGTAAGTGTCATTGAATAATAAGTACCTCAGTTGATCGTAAGCAGTTACTTTTGTAATTGGATTTTTACTTCCTCCATTTTCAAATGCATATCCATAAAACACTGGATTATTATCTACTTTAAAGCTTATTACATCACCATTAGTTATAGTAATTTGCTTATCTTTTAATATCTCAAAATCCAAACTAGAGGGTTTATCTTTTCTTTTAGTTTTCCAGGTAACTTCACTTGTTAATTCAGATATATCAAATATCTCTCCTTTTTTATTATCTAGTAACAATTGTATATTCACATTAATCCACCACCTCTATGGTAACCTTAAAACTTGTCCTGTATATATTAAGTTAGGATTCTTAATCTTATCTTTATTCAAATTATAAATTTGTGGCCACTTATTACCATCTCCTAGGTATCGTTTAGCTATGTGCCACAGTGTATCATTACCACTAACTGTATGTGTTTTAGGTTTATTAGTATTGCTTGGCCTTGCAGCCTTGGAATTCGCTATTACTTTTTTCACAGATTGATTAGCGGCTGCAGTTTTTGGTGTTACTATAACTACTTTTTTAGCAGCATAGTTTTTATATCTTTTAAGTTCTATAGAATAATGTATATCTCCAACTTCTCCCCCTTCTTCGCTGGGTTTAAAACTTTCTATAGTAAATAAATCATTTACTTCTAGAGGACTTCCTACAAATATAAATCTTATCTTTTGTTTTTTATTTCTCCATTCTCTAATCTTTGCAATATAAAAGCTCGGTTCAAATAATTGCTCCGAGCTTACATAAGGACCTTTATGCTTGGGAAAGAAACTTTCAAAACTTATTTCAGTTAACTTGGGTAAATTTATTGTATTAATTTCTCCTAAATTAATTACATCGTATGTTTTATTATTTCCATCTTCGTCAAACTCAATTTTTTCTGGGAGTACAGGGAGGACGAAACCTTCTTCACCCTCATTAATTCCTAAATACATTTTATACATTAAGCATATACCCCCTCGGCACTGTTAGCCAATTCATTTTCCATGTAGTTCTCTATCTTAGATATTATTTTGTTTATGTCTGCTTCTTCTTTAATATCCCCAGTAGTAACTTGTACTGTTGGAGTTAGAGTTACAAAGTTTTGTATGCTTTCCATTTCTGCTAAATCTCTCATCATTTCTAAGTGTTCATTGCTAATATCTATTTTATCGTCTATATTTTTAAGATGATTGTTAGCATCTTTCAATCCTTTGTTTCCGCTTGGGGATTTACTACCTTTATTTTTGCCATCATCTCCTGCAGTTCCTAATGTTCCTGGTCCTTGTGCTTTATTCCATGCCGCCATATCTGGCATTTTACCCATATCTGGAATATTACCTTTATTAAATATATTTCCTAAATCAAATTTATCACCTATGTTTTTACCCACGCCATACCCTGAATCATATGCTTTACCATATTCAAATCTATCCAAATGCATTGCAGAAGAATCCATCTTTTGAAATTGAATTTTAGGTTTACCAACTAATTTATCAACAGCACCTTGAAGTCCATTTTGCCAATTACCTACTGCATTGGCAAGGTTCGAGCCGAATATCGTATCTATAGCGGAGGCTATACTTTTAAGTATCCCTAAAACTTCATCTGCCATTGCTGCAAATAGCCTAATTATAGAACCTATAGGATCATTAAATACATTAGCGAAGAACTCGGCAAATGCAGCAAAATGATTATAAAACAAAGCTATAATATCAACAACTAAATTATAAAATGCTACAAATAAATTTCCTATAAAAGCAAGTGCTACCATAAATGATCCCGCAATAACTCCAGTGGCTGAAATACTTGTACCCGCTAAATGATTAACCCCCGCCACCGCTGCATAAAATAAAGCTATTAATATAATTATTGCAATAATAATCCAAGTAATAGGACATAACGCTAATGCTGCATTTAATCCCTCTTGTGCAATTGTTAAAGCAATTACAGCCGCCGTTTCTGCCCAAGATGCAATAGTATGTCCAATTTTAGCTCCGATATCCATTATAGTTGTTAACCATGCAATTCCCATTGTTGCATTATAAGCTATCATTGCAGCTACAATTCCCCAAACAATAGGACTAATTATGCTCCAATTATCACTAACCGCTTGACCTAGCCATGTAACAATGTCTATAGCATCCATTATTAAATTCACGATTATATCCAAGCCTACACTTATGCCATTAAAAAACCCTTCAAAACTTCCATTTTTAAATCCTTCATTTATTCTGCTAAGCAAAGGTTTTAAAACTTCTAACGCAGTTTCACTTGCCTGTGCAAACGCAGTTTCTATGTTTGATTTAAGGTTATTAAGTTGAGCTATTGCAGATTGATTAAATTCTTCCAAAGCTTTATCAGTAGCACCTTTTTTAGCTAATAATTCATCAAACTTGCTTATAAACTCATCCATAGACTTTGACGCTTTTAATATTTCAGCGTCAGCTTTACCAAATCCAAATCTAGATTTTAAGGACATAAAGTCTCCTCCTAAAGCCTCTTTTAATGCAAATCCTGCACCTTCTAATCCCTGTGTTGGATCTAAGAACGCTAGTTTTTCAGCTGTCTTATTTAAGTCCATAAGTTTATCTGTATTTTTTGTAAACTGTATAAATGATCGTGTTATGGTATTAAACTCTTTTAATCCATATACACTCTCATTTGCATATTTGTTGAGATTTTCAAAAAAAGCTTTCCCTATATCTTTGTTACCCAACATACCACTTATAGTAATTAATTGTTGCTCTAGTCTTGCTCCTCCTCCTACAGTTAAATCCATACCCTTTTTTACAGCTTGGAACCCCAAATAAGCACCCAGCAAATTTTTTACTTTACTTGTTAACCCATTTGCTTCACTAGATCCTCTATTAAAAGATTCATTTAATCTATTTTGATTGTTTTGAGCTCTGTCTTGCTGATTAACTAATTCTTGTAATCCAGCAGAAGCTCTTTGAATCGCTCCTCTTGCAGTGTTTAAAGTATTTGTTATTCTTATATCCCTATTAGCTGAATTATTTAGATTATCCATAGCACTTATAGTTAAATTTAAAGCTTGTGTAACTTGCTGTAATGGTCTCGTCATTTGGTCAAACATTTTAAGAGCCGTTGATACTGTTGCCATCTTTACCTCCTTTCTAGCATAATAAAAGCACCCACATTAAAGTAAGTGCTTTTTCCTTTATTTATTTAATAGTTTATTTTTTTCAGAGGTAAATTCCTCTTGTGTTAATATTCCTTCATCTAATAATCCCTTTAATTTTATTAATTCGTCTGCCACAGATGTTTTGGTATTTATATTTTTATCACTAGTCTTCTGAGTAATTATAGACAACATTGAAAGTATTTCTTGAGCTGAAGAATATGCTGTTTTGTATATAAATGAGTTGTCCTTTGTTGGTGTCTTTATTAAATCTATGTAAACACTTGGATTACTAGTATCATTAACAGTTATTTTAATTCTTAAATTATTAATCACAGATTTAGTTTTCTTTTTACCAGTTACTCCACCAACAACTGCCCCAACTCCTCCTAATAATACACCACCAGCAACTGCTCTTCCAAGCCCACCTTTTGTTATACTATCACCATCCTGTAAAAGTTCATATTCTACAATATCACCAAAAGCATGTATTCTAGGATTAACTTTCTTGCCTCCAAATCCGTCTGGTATAAGCCATAATCCTTTTTGTTCATCAAATTCTATATAAGGTCCTATTTTTTTAGTAGTTGTAAAATCAGCTACTAATTTTTTATTATTTTTATTCTTTTCCATTTCAATTAATATTGCTTCTTTTGTTGTATTTTTATTTATTTTTACTTGAAAATTAATACTACACAAATGTAAACACTGTTTACAGATAAATCCGCTAGATATTTTCTTTTTTCCTTCTTCATTACCACAAATACAACACTTTTCTTTACTTTTAAAAAATAATCCCATGTTAGCATCCCCCTTATTAAATCATTTTAATAATAGCAAATAATGGGGTTTGTTTCAATATTATCTTTTTCTTTTAGTTTTATCCGCTTGTTTCTTTTCATTCTCTATATGCAAATCTATGGAAGCATATATAAAAGCCCTTTCTTTTCTATTCATATTTATTAATGTACTAGGAAGAATCTTTAACCTGTGGAGAGCATAGTGAGCATAATTAGCTTCACCATCCCCTCCCTTGATTAGTTTTTTGCTTCTTCTACTAACTCCTGCATACCTTTATCGTATCCATTTATTTCTATAACAGTGCTTGACCAATCTGCATACTCACCATCAGTCATTCTTGACTTCATTGCACTTAAAAGCTCCTCTGCACCTATTACTCCCCAAGCCTTTTGTAGTTCTGAATTTTTTAAATCTGGATATATCGTAGTTTCTATTATTTGATTACTTACAAATTTATCCTGGTCAGTTTCAATCATTTTTTGACCCTTAACTAATTTTACCTTTTTGCATTTCTTTCTAAGTTCGTCACCTTTATCAGCACTTATCGGTTTAAATTTCATTTTCTTCTTTTTGCCACCTATAGTTATTTCTCTTTCTATTTCTTCTACTTCCTCAAAACTATCCATTAAGAAATCTTCAAAATTATTCATATAATATTCTCCTCTCATTATCCTAATACTGGTTTGCTAAATTTATCTAATAAATCTACATCATCAAATGTGAATCCTATTTCTTCTTCTAATGAATCTGAATCTACGTCAAGTAATGCCATTGGACATTCATCTAAATTACAATTTTTAAGTACTGTTGTTTGTTTTCCTACAGTACTTGTTGGATCTTCATTTACTACAGTCATATCAAAATAAGTATCTATACCTTCTTTCATATATTTAATCATCATTTCTCTAAATAAAGATGTTATATAGTAAATTGTTAATGTACCAGTTCCCTTATATCCTTTTGCTTTACTTTGTGTTCCTCTTTTACCTAAGGTTTTACCCTCACTTTTTTCTTTTTCAACCTTTGATTCAATTTTCTTTGCATAAAATAATTCTTCATTTCGACCATCTATTGTTGCGTATGCCCTTCCTTCTTGTCCACTTATTGTATCCTTAAACTCTAAAAAAGACATTTACTATTCCACCTCCACATCCATATATAACTTTTCCATAGCATCTATTGGTTGTACCCCCATTCTAGCTACTACAGAATCTTTATCCTGTCCTCTTTTAATTTCAACATCTTCTGGAACAACATTCTCAAGTCCTCCAATTCCCTGTAATTTTTCTAAGAACTTAATTACATCCTTTTTATATAAATTTCTTCCATCTTCGCTATTATCACCTTTACCAATATAATTGGTTTCCCATAATAGCCTACTGCCATTATTCACTTCAAATAAAGTTCTTACAACTCTATTCTTTCTATAGTCTTTTCCTTTATCTTCTGTAAAACTTTTAAATGTATTAATATCCTGCTCTATTACTACTTTTCTATTACTAATAGTAAAGACTATTTCTCCGTTTAATAAAGCTTCTTCTATTTCTCTGTTGGTGTATTTAGTATCTACATCAATGGCACCTGGATATTCTAGATAGGTGTTTGATTGATTTACATTTGCCCCAGCAGTAGCTCCTGTTAAAAATGCAACTGCTTTATCAGATTTTATTATTGTTTCATCACTTAAAATTACACCATTCTTAACACTAATAACATTTTCACTATCAGCTTCGGGATAATTTTCTAGTATCAACTGCACCTGTCTACCATCTTCTTTAAGTCTCTTTATAAATGTAGTGGCTACTGCTTTTATAGTAGGATCTTTAGTTGGAATACCCATGGCATGAAATTCATAAGGTTCAATAGTTGCCAAATAATCAGTATATCCTTGATTGGTAACATTACCATCAGCTCCACCTTTAAGTGGTAATCCAGCGGAGGTTTTTAAGTCTCCAGTTCCTTTAAAATCAACATAATCATTATCTTTCAAGTCTTCTATAGTTTTTACTAATTGCTTATCCACCTTATTTCCTTCAAATATAGTAATAACTTCAAAACTTTCTGTAAAATCTATACTGTTTTGGATTATTACAGTAATATTATTCCCTTTGGTTCCAGTGCATTTAGCATTTATTGTTAGTCCCTCCAATGTAGCAGTAGCCTTAGTACCTTCATTAAGTCTATACAATAAAAGTATCTTAGCTTTCTTTAATACTTCTCTAATAAGTAATGCACTTTCATCAGCTATATTTATACCTAATACTTTAGATAAATCATCATCAGCATATATCGGCAATACTTGCTTTTCAGGTCCCCAAGGTAATTCCAATGGTAGAGTTGCAATTCCTCTTTCTCCTATTGGCGTTTGACCATTTTTCTTTGACTTAAAATTTATATAAGCCCCGGGTCTGATTTTATTTTGTCTTTCCCAAGTTCCACCAGCCATATTATTTCACCTCTTTTTTATTAAACTTTTCTAATATTTTTTTAACTTCATCTATGCTATATTGTTCATTTTCTAGTAGTGCTTTAAGTATATCTTTTTCTATAACTGTAAATTGCCTTGAATTTACTATTTGTTCTTTAGTAAATTTAATTTCTTGTTCTTTATCTGCCATTTAAATATACCTCCTGTTTTAATTTATTCATTTTAGGAGCTTTTTCAATTTCCTTAAGCACATGATAATTAAATTGCAACATGAAGTGTAAAACTCCATCTATAACCTCATGTGTCATTTTACTAGATCTATATAAACTATTATTTACTTTTACATATTCAAGCACTTCATAAAGCTTCTCAACCATATCATTATAATCATTATTTAAATCCTCTTTATCACTAAAATAATGAATATCAAAAGATATATTTTTCTTATATCTAATATTAAGTTCCTTACCTTGGCCTGAACTTAAAACCTTAATAAAAAAACAAGGCTCCTCAAAGTCTTGTTTTATTTCTTCTCCATATATATTTATGTTAGGAAATTCTTTATCCAATGTTTGATTAATCCCTATTCTTAAATCATTTATATTTGATATGTTATCACCTACTTTAACAACACTCGAGTTGTTATTATAAATAATGCAGTTACAATAAATATTAATAAATCAAATATTGCCTCTAGTTTCTTTCCTTGCCTAAATTCACTTAATGAATGATAAATTACAACAATCATATAAAATAATAACCCAATAGCTAAAACTATCTTCATATTATCACTTCCTTTAAGCTCTACCATTAAGTATTTGATTCAATAATTCTACTTGTTTTCGTTCTAAAAACTTAGGTAATTGTCTTTCAATCTCTTGCATTGATATTGTGGCCATGAATCTACCTTCAACCCAACCTTTATGGTTTTTAGTTCTATGCCCATACTCAACATAAGAAGCATATTCAGTATTATTAAATATCTCCACTACATAAGAGTCACCTTGCTTTATTACATTTCCTACTTGCCAGTTACGTCTTAAATGTCCTCCTGTTTTAGAGCTACTAGTTGTAAAGTTTACTTCTTTACCATCCTTAGTTGTAAAGGACACTTGATTGCTATAAACACCTACTGGAGTTCTTTTTTTAATCTTTCTTTCAGCTCTAAATGCCATCTCCAACAAAAATTCTCTTATCCATCTTTCAATTACTCTTTCATCAAGTGCCTTTTGAAAACTCTTGGTCATATTTTTAAAATCAGAGTAATCAAAACTCGCTAATCTAGCCATTAAGCTTTATCCTCTTTATTTAAAATAACTTCCTGGTGTGTATAATAAGGAAATCCTTCTCCAGCTTTATATTTAGTTATAATCCCAAATTGGTTAGTAATTTCTATTTCATCACCTTGTTTAATTTCAACTTCAGGAGCTATAAAAAGTTTAATCTCATATAGAACTTTGTTTACTGTATCGGTTTGGTTATTTTTCGATAAACTTTGCTTAGATATTTTACAAGATTGTTTTTCATATTTTATTTTTGGTATTAATTTAGTTTCTTTAGTAACAGGATCTTTAACCTTTTCTTTTCCTCCGGTTATATTACAAGTGCAATCGTATAAACTTTCAATAGCTTTTCTTGCTTGCTTTCTAGCCTTTTCTATACCTTTAAGCATATTACCAAACCAACTTTCTATATTTATGAAGTTTAGCTTTATAGTCTTTTACTAGGCTATCCTTAAATTCAGCATTAGCACTCCTATAGCTTATAGAAGTATCCCCTTCACTTATAGAGGAAATGGAACCTAAAGGATTCTCTTCTTCCCCTAGGTTCTCATTTCTGTATATGTCTATAGCCATTCTTAAAATAGTATTATTTAATTGTTCTGGGATTTCTTTTATGTGACAATAATCCCTTATTGTTTGTTCAGCATCCTCTATGGCGAATTGCAATGAAAAATCCTTGGAGTCATTATCCAAGGATATACCTAAAAGTTTTTTTAATTTTTCTAGTGGAGTCATTAAACTCACCTTCTTATATTTTATGTTTAAATGCAACTATTCTTATTTGTTTTGGTTCATATACTCTTTCCCAGTTAGTTTTTTCTTGTAATTCAGCTCTACTTGGCCCTTCTGTTTTTGCTACTTTAGCATTAGTAAATTTAATTCCTCTAGGATGAAGAATCATAGTCTTTCTATTAATTAAATAATCAACACCTGAACCTTTCTTTTTATCTCTATCAGTTTCAGTTGGTACAAATCCTACTGGATTACCATTACCTAACGCTAAAGCTCCTTGTCCAAATAAATAAGTAGTATAAACACCGCCTGCATCAATTGGACAGCCATCATCAACTATTACTCTCTTATCTTGATATACATCAAACTCTGGACTATCACTTGGTCTTATTGTTTCAATTAAGTTTTGTTTCTTTAACTCTGATTTAACAGCGCTGTGCATCATAACACCTGTTAAAAGTTCTTGTGCATCTCCTAGCATCTGTTGAGCATCTATAAAAGCACTTGCTGACCACTTAGCTGCTCCTTCTGTCATAGCTGATATATCAAGTAAGTTATTTTTCATTGATGTACTTAAGAATACACCCTTAAGAATTGCAATTAATTCTTTCTGCATATCTCTAGTCCAAAATCCACTTACTAATTCTCCTATAGCTGCCATTGGATCTTTACCAGCAAGTGCAGCTGACAAATCTGTAGCACTCCACATTTTAGCCCTTCTTAAAATAGCTGCTACATCTTTATTACTCGTAATCTTAGCTGCTTCTAAGTCTGTATCTTCAATTATTTGTTCTGACTCTCCTGTTAAATCCTCGAAGAATGGCATATTAATTAAAGGACTTGCCTGTGAAGCTAAGCCATCAAATTCACTGTTATTTGTTATAATCCCACTTTGTACTAAAGCACTCTTCTCCATTGTTCTATTAACCACATAAGGGTTAAATAATTCTGGTACAATTACATCACTTAATTTTGTTCCCATATTTCACACATCTCCTTTATTATTGATTTATTCCAACTTGAGCCATTAATTGTTTGGCCTGTTCTGGATTTTCTTTAAATATTTTACCTTGATCTGTTAGATTAAAACTTTCTTTTTTCCAAGGATTATAACCTTGTGATGTTTTACTTCCATCTGTAGGTTCTACTCCTGAAAACTTAGGTTTTTGTTCTTCTGCAAATAAATAACTATCGCTTTTTTGTAATGCTTCTATTTGCTCTTTAAGTCCTAAAATATTCTCGCCATCTAATTTAACTCCTTCTAAATTTAAAAGAGCTTTAACAGCCTTTGTGTTTCTTACATTGGCACCTTTTAAAGCTCCTTCTAATGCATAATTAAATTGCATATCCTGTATTTTCTTTTCATAGTCTTTAACCTTGGTTTCATAATCTGTAACCTTGATTTGAAGTTCTTCATTATCTTTATTACTTTTCTTTAAATCAGTAATAGTTGTATCAGCATTTTTAAGCTGCTCATCTAAAGCATCAAATTTATCTTTAGTAATATATTGCTTACTATCTACTAAATCAACATCCTTGTATTTAGCTTGTAACTCCTCTGGTATTTGAGAATAAAATTCTTCTAAAATCTCACTTAATTTTGGCATATTATTTACTCCTTTCAAAATTATTCTACTAATTCATATGTCTTTTTAAAAATATCTGGTTTGCATGGATAAAACTCTCCATTCACCCCTTTAATAATGTAATCACCTTTATTTGCAATCATAGTTCCTTCCAGTGTTTTAATTAACAAATTGCCTTTTTCTTCTCTAATAACTCCATCCCTGTATGCTTCATAAAATGACATATCTTCAATTTCAGTAGTATTTACATCTCCTGTATACTGAACAGCTTCTACTATAACCGGTTTCTTTTTATACTTAGCCATTACTATCACCTCCTAATTATTTATTATTTGTACCTAAAACATTTCTATCTATTCTATCTTCAACACGTCTATTAAGCCACATTAAAGCCTCTTCTATATGTTTAAGAGCCTTTTCATTGTATTCACAAGCATAAGGACCTTCTTGAAAACCTTGTAATCTATTTCTTACTATTTCTAATAAATCTGTATCTAGTATACCATTGGTTGAACTTCCTTCTTTACGAGGTCCTTTTTGAAAATTTATATCTACTAGTACACTGTCTAAAATATCTTTATCTTTTTTACATATCATATAAACATGATTGGCTCCACCTGGACCCTTATCATCCAATACATAAACCTCGTTTAATTTTTCTCTTTTTTGAATGGTATTTAATTTGTACATTTATATCATTCCTTTCTTAGCCCTTTAATCCTATCTTTTTACTGTATAAACATTAATTTTTTCACCTTGTGGTCTATGAAATTCATCATTAATTGGTTCTATGTCAATATCATATCCATTACCAATTAGTGCTTCTGTTACTATATCGGCAATACGAAAATCTCCGCTAAATTTAAATATAGCTGCTTTTATTCTTTGTACTCCATGAGTTGACACATCATTCATTATTTTCACCTCCATTTTAAGCAATATATTTCTCATACCATTGCTTGTAATTTGTTTTCCCATCTACATAATAAATCTCACCTTCATAATCTCTAGTTATTCTTTCTATATCTATTGTATCTGGAAAATAAGGAATTATTGTAGTTCTGCAATTAGGGTGAAATGGTGGAGCATTAACTCCTATTTCTTTTTCAGATACTTTAAATACTTTTCCATCCAATGATCTACATATTTTACTCGTATGTAAGTCTAAAGTAGCAAGTATTTCATATTCTTTAACAACTCCACTTCCAATATAGCTGTTAAAGGTTGATTTAGAAACAATATTAGCACTTTCAGTATTAACTAATGTTCTAGCTCTGCTTTTACCTACTTCCATTCTTTCAGCTATCACCTTAGAAGTTTTATCTATAGAATCTCCGCGAATAAAAGATTGAGTGAGATTGGTTTGTAGCTCCATTATTAACTTTTCTTTATTGTTCCATATCCTACTACTATAATTATCACCATGCCACGGCTCTGTAATTACTTTGTTAATTATATTAGTATCTAACTTTGCAAAATTAATACCGATTCCCAATCCTTTGTGTACTTCAAAGATATTCCTATAATAAGTATCTTCATATATTCCACTTAAAATATTACTAGTGTCATTTCGTTGCTTAGTATACAAATTCTCTATTTGATTTCTTATTTGGGTTTGTAGAGCTTGTAACCTAGTAACTCTTACCTTATAAGATACATTGTTTAATTCTTTTTCCCATTGTAGATTTTTATTATCTTTAGCCTTTCGAGTAAACTCTTTTAAGTCCATCTTAAACTCATGTAGTTCATTTGAATTTAATAAACGTCTAGCTTCTTGTAAAGATATTTCATTGTTTTGAGAAAATCTAGCGTAAAAGACTTCTATATCTTTTTGTATACTACTTAAAGCTTCTATATACTCTAAATGTAAACTTAGAATATAATTATCTGTTTTCTTAAACTGTTTACTAGCTACAACTTCAGAACGTTTCTTCCAATAGTCTTTACTCCTCATTCTCTTCATCCTCTTCATCCTCTGGTGTTTCTTCTAAAGGAAAATTGGGATACATTGATTCACGTTCTTCTTTCTGTTTTTTTATCTTTTCTAGTTCATCTTTAGTGGCCCATGGATGATTAGCTACTATGGTTTCATCTGATATAATGCCAACACTACTTTGACAATTATTAATACTATCAGTTTCATTTATAAGGGTATCCCTATTAAACACAAATTCTACATTTTCATTAGTAAAGTCACCTTGTCCAGTATTAATTAAATGTTGATTCACAAACCACAATAAATATTCAAGTGATGCCTGGAATTCTGTTTCTATTATGTTGCAATCCATATCTAAATCATTATATAAAAACTTAAGAGCAATGCCACTTGGAGAGTTTCCAAATTTATCTGATTGAGTATCAACTCCCCTACCAAATTCATAAATATCTTTTCTAGTTTGTTCTATATGAGTTTTATAAGCTTCAACATTAATTTCTAAGTTTCTTGTTTCAACTCCACCATCTCCTGTAACTTTAACAGCTCTATATAAGGACATATTTTTTCTAAACTCTCCTAAGTTAGTTCCATCATAATCCTTAAGCACATAAATAGAGTTTGGAAGGTCCTCCAAGTTATTACTATTGTCACTTTTATTTCTGTCATAATCATCTACTAAAGATTTTACAAACTTAATTAATGGCTGCTCTTCATCATTGTACTTAAAATAAATAAATGGTACCTTTGACCATGTGAATGATTGCTTGGTACCATCTTTATTAATTATACTAAAATGCCCTTCATCTTCTGGAGCTTCAACATCAGTTATCAACTTACCATTATCGTTAATATATCGTAACACTTGTTTCGTGTCCCAGTATTCAACTTTTTGTACTGTCTTTTTAGTCTTACCTTCATAAACTATAACTTCATATACCCTAATAAGTGCATCTAATTTTGTATGCTCTGAATCTTTCCATAGTGGAATAATCTCTTCACTAGGTAATCTTTTAAATCGTAGTTCACCATCTGAATTATAATAAATTTGAGCCCATGCTATACCTTTATTAATGGCATCTTTACCTAAATTCTTAAGTAATCTCATAAAGGACTTATTAAATATATCATCTAATACATTTTTATATGTTTCGTTATCAGTTTGTACACTTAAAGGCTTACTTAATAAATAACCCACTTTCTGGTCTGCGAGCTTTCTAACAAATTGATGTACTAGTTTATTATTTGCTAAGTTCTTAACTTCTTCTAATTCTCCATCTTCACCTATAGCCATTCTTTTGCGTTTTAGTATATCAGTATCACCTTTATAATATCTTTCTCCATCTAACATTAATTGTCTTGTTTGTGAACTATTCCATTCTTTTATTTCCTCTTGAATAATTTCTTCTAAGCTCATTACTGAATTAGATCCATTACTTAATATCTTATCTATAAAAAACATCTAAACACCTCCTTAATCAAATGAAATTGAATTACCTTTTCCTACATTTTCTGCCACACCTGTTGTTGCATCTGGAGCGTCATCATGTTTATTCTTACCTTCACGTTGGTATTTGTTCATTGCCTTATAATATTCTGGCCATTTATCTCTCCAGTTAATTGGATAATATATATGGTCCATAACCCACGTAGCATTAGAAAGTATTCTAGCCTTTTTATTCTTACTTTGATGAAACCACTTAACCTTTGTTTTATTGCTATTGAATTTCTCTTTTAATATCCTCTCTGCACTTCTTGCAAATCCACGTCCACCGTTATTACTCTCTATATCTGCTATATTAACTTCATTTTCATAAAGCATTTTAGCTGTTGCGGTTTCTGTAACTTCCATAGGCTCCTTAGTATATAAAACATCTAATACATAAGCTTCCTTATTATATTCACCATAAACAATACAACATAAGTAATCTGAACCTTCATCAGCAGTATCTATATAAGCTTTAATTCTAGTAAACAGTGGATTACCATTATTATCTTTAGGTATATATTTATATTTCTTAAAATCACTATATAATCTTCCTTTTAAGTCTATAGGTTCCTGTTGATAGTTAGCACTGGCTATATCTTCACCCATAGCTTTTACTTTATTTATATAGCTCCTATAACTTAAAACTTCAGGGCAAAGCATTTCCTTCTTTTCTTTATTAACTAATGCTTTCATAGAAATATGTTTAACTTTTATACCCTGTTCTCTATAATAATCCAACGCCCTGCCAGCTAAATCACCGCTGGCCCATCTAGTCATTATGATTATTATCTTTCCACCTTCTTCAAGTCTAGATAACATGGTATTAGTAAACCAGTCCCAATGTTTTTCTAATACTGCTTCATTATAAGCTTCTTCAGCATTTTTAATTAAATCGTCTATAATTAACAGTGAAGCTCCAAATCCTGTGGCTGTACCTGTTGGAGAAGTGGCCAAGTAGTTATTATATCCACCTTCTAAGCTCCATAGGTTCATAGCTCCATCACCGTGTTTTATTCTTACTCCTGGAAATACATCACTAAATACTGGTTTATATTTATCTGCTTTTTCTTCCTGGATGGAATTTCTTACATTCTTAGAAAACATAGTAGATAAAGTTTCATTATATGATCCTGTCATTATCTTTTCATTCTGATTATTACCAAGAACCCATTCAACAAATAACCCTGCTGTTCTTGATTTGCCGTGTCTAGGAGGTTCATTTACTATCATTACTTCCTCATCTGAAGAAAGAAACTCTTGAAATTCATTACATAGTTCTATTAGATATGTTCTATTTTGTTTATAAAAATCTGGTGCTTTTAAATTGCAATAAAAAAAGAACTTACGTCTTGCAAGTTCTATCTTTGCTCCTAATTGTATTAATTCTTTATCCATCTTCTTCACCAGCTAATTTTAATAGCTGCTCTGTAGTTAAATCTTGAAAAGGATTATTTACATTCATATCTCCACTTAGTTCAACTTTATCCTTAAACATACCTAGGTGCTTACCTAATAATTCTAAGGCCTTTACTTTATCACAACTTTCAACTGCTATTCCAAATTTAGTTTGTTTAATAGCTGCTATAGCTTTCTTTTTATCTTCTGGTAAATCATCTGTCAATGTTAGTTCAACATCTTTGTAAAATACTTCTTCTTCATCTATCTTATTGCCTTCTTTGTCATATACAGGCTTTATATAAGACTTTTGAACCACTTTAGCATAATTAGAACCATTAGATTTAGCTATAGCATAAAGTTCCTTTAAAACAAAGTCTTGAGTTATTTCTGTTCTTTTTTCTCTATCTTTGATTTTCTTATCTATATATTCTTTTATCTTTGGTTTATCTAATAATTCATAAGCATGAGCCATAGCATATTTTTTACTATAACCTGACCTTACTGCTGCTTGTGTGACATTAAGGTCTATTAAATATTCATCACAAAATTTCTTTTGCTTATGTGTTAACTTGGCCATTAATGCCACCTCCTTTATAAATATAAAAAAGGCACCTAGAAATTAATCTAAGTGCTTTTAGTACATAAACACATTTTTGTAGTTATATATTTTTTCTCAATACCATATTATAATATTAGCTTAAGTACGTCAATCCATATAAAAAGGACATGATTTTCTACTCGTATTTTACTTTAAATGGCTAATTCAAGGGCTTTATCTATATAACATAAAGGACATTTTTTATAATCTTATCCCATCAATTCCGAAAAATAATACACTCAAATCTTCAATAGACGACTTTATATCTCTACTAACTGTTTTAACATTTATATTAAAATGCTCTGCTACCTCCTCATAAGTTGGTGTGTTACTATTTCCTGGCGAATCCATGTAAATATATTTTATTATATTATATCTTCTTTCTTTGTTTTTACCTTCATTTTTACATATAGATTGATAGTAGCTTATTGCTTTATTCATATGCTCTATTATTATCAAAGTTCTTATTTTAGTTCTACATATAGCTTGTACATATTGTTCTTCATCATTAATACTATCTATTTCGTCCAGTATATCAATTGCATTTTCTTCATTAACTTGTCTTACTGCATTATTTGCTATTTTATTATGGATATTCAATGTTCTATAGTGTTTAAGTAATAATCTAGTATTTCTTAAACGTCTATCATATCTTTTTGTTGTCTTATGATATTCCTGTTCTTTTATATATTTTATGCCTTCCCTAATTCCAATTTTAACAGCTTCTTCATATGTTATATTATTTTGTTCCACAATATAGCCCCTCCTGTTCTTTTAATTCTATGTCAATATTAGCTTTTGATGTCCATTTTCTTTCATCTATCAACTTAACCCTATGCTCTTCATTGAGTTCTTTTATTAAATTAGGTTCATCTAATGTTAAGGCTTTTCTGTGGCATTTCCATAAAACTAGTATACACATTTGTATTAAATCATAAGTTTCTCTAATTATATCTTTTAAGTTAATAAGTCTTTTATTATTTTCATATTTTTGTATAGCCTCGATTACCTCCTTATATTCTTCTGTAATCTTAGTTATTAATTCTTTTGATGTTATTGTTGTATTATCTATTTTAAGCTTGTCATTCTTCCTAAGTACTTGCATTAATAGTTTCATACCGATATTTACCTACTTTCCTTTAATCTTGCTTTTACTGCTTCTAGTAATACGTTCTGATTAACTTCTTTACTATCTAAAGCTTTTATAACATCTTCATCTACAGTATCTTTACTTACTAGATGATGTATTATAACGCTTTCCTTTTGTCCTTGTCTATGAAGTCTTGCATTAGCCTGTTGATATAACTCCAAACTCCATGTAAGCCCAAACCAAACAATAATATTGCCACCATATTGAAGATTTAATCCATGCCCTGCTGAAGCTGGGTGTACTAAAAGTATAGGTATTTCTCCATTATTCCATTTTTTAATATCCTTTGAATCCTCTAATCCTATTGCATTTAACTTTTTAGTTTTTAAGAAATTAACTATTCTATCAAAATCATGCTTAAAGCTATAAAATATTAAAACTGGTTTACCATTGGCTGCCTCTATAATATCTAATAAAGCTTTTAATTTTTCTTCATGAATTTCTAACACAGACTTGTCCTCTGAATATATTGCCCCATTAGACATTTGTAATAACTTATTAGTAAGTACTGCTGCATTTGTAGCTGTTATATCATCTTCTCCTAATTCTATTACAAGATCCTTTTCTAGTTGCTTATATTTATCCATAGATTGTTTTGGCAAATTAATATTTATGACATTGTCAATTCTTGCAGGAATATCTAAATAATCTTTGGCCATCATGGAAATACAAATATCACCTATCTTTTTATGGATCTGTTCTTCTGCCCCTTCTTTTAGCTCCCAGTTATAAACTACATATTGATTTCTTCTTCCTGGATTAAAATATTGCTGTCTATAACTTGTAATAGTTTTTCCTAGCCTTTTACCACCATCTAACAAATAAATTTGTGGCCATAAATCTATTAAACTATTAGGTGCTGGTGTACCAGTAAGTCCTACTATCCTTTTAAAGTATGGCCTAACTTTCTTTAAAGCTCTAAACCTTTTAGCTTTAGAAGATTTAAAAGAACTTAACTCATCTATAACTACCATATCCCATAACCAACTACTAAAACATTCATTAACTAACCAATCTATATTTTCTCTATTAGTTACATAAATATCCGCATCTTTCATTAAAGCCTCTCTTCTCTGTTTCTTAGTTCCTAAGATTTTTGATACTCTTAAATGACTAATATGATCCCATTTATCTACTTCTGTACTCCAAGTATCTTCTGCTACTCTTAAGGGCGCTATTACTAAAATTTTATTTATATCTCCAAGAAATAATAAATTATCTATTGCAGTTAATGTACTGATAGTTTTCCCCATTCCCATATCAAGGAATAGACCTGCTGCTGGATTATTTATTATGTGCTTTATTGCATATTCTTGGTAACTCCAAGGTTTAAAATCCATAATTACTCATCCCTAATCATTACATATTCTTTACCATTAGTATTATCAAAAATTCCAACATATTTAGTACCTTTTTTAGTTTCGCATGGTATTAATGCTATATTAAATTCAACACATAACTTATGGATCACTTCCATTATAAAACTTATCTCTTCTTTTCTTTCACTCATTTTTAATCCCCTCTACAAAATTATTTATCCTCTCAATACTATCTATAATTTCAACTCTGAATCCTAAAGATCTTAATTCCTTAATCCTATATTTTTGTATAGGTCTTGGTTTTTTACCTGGTGCTTTAAGCTCTACAAAAATAATCCTTCCTTCTGGTAATAAAACAATCCTATCAGGCACTCCTGACACTCCTGGACTTACAAACTTTAAAGCCTTACCACCTAACTTCTCAATTTCTTTTTTAAGCCTTTTTTCAATCCTTGATTCTTCTATTTAAATCACCTTCCAATTTTTAGGTGTTACCATGTTACCAAAGTTTCTATATAATATATATCCGTGTTATTAGGCATATGGGTATATATACGTATACGCCTAATTATATAAATACTACTTATATATAATATTTTGGTAACATTGGTAACACTAGCTATATAAGCATTGATATATCTAGCTTTAAGGTGTTACCAAAAGCGTTACCAAAGTGATTTTTAATGGTAACATTGGTAACATCCTTTAATTTAACTTTGGTAACGCTAAATTTTACGTATATAAGCTCTTTGAATACCATAGACTTTACCAAATCTCAATTTACTTTTATGTCTTTCCCATCCTTTAAGCCCTTTTAAAATATCGTTAATTTCTCTACTGTGTAATGGTGTAAGCTGTTTAGGATCTCCGTTGAAAAGTTCTACCCATATTTCCATAACACAAGTTTTATCTCGCCTTAAATTACCCTCCGGGATTTCTCCAAAATCAGTACCTTGTATATAATTTCTTCTCTCAGATAATCCTAAACTATACCAATCATCAGGCAATAGCTTATTAAGATATTCTTCAATTAATCCAGTTTTTGCGCTTTCTTCACTATGCGCATCTTGCTGTTTTTCGGCTTCTTTTTTCTCTTCATTATTTAAATTTAAAGGTTCTTTATTTTTCCATAGTTCCACAGCTTCGGCCCATATTTGATTGATTTCATAATCTGTTAAATCACTCCATACATATTTATTATGTTTTTGAGTACCTACATCAACTGGCCAAAACCTTCTAGAACCTGTTTTATCTCTTAAAAATTCTTTATCATTAGTAGTACCTATAAATATACATTGTCTTGGGAAACGGCTTGTTCTTCTACCATAAGCCACCCTATAAATATCCTCTTGTTTAGATAAAAAATGTTTTGTTGCTTCAATATCTGCTTTTTTAGTTGCTGTCATTTCTCCCATTTCAATTAACCAAAAACCTTGAAGTTGTTCATAAGCTTCTTTACCACTTACGGTTGTCAAACTATCACTATACCAATCCTTACCTAGTTTTTTTATTATAGTGCTTTTACCTATTCCCTGTGGTCCACTTAAAACAAGCATAGTATCAAATTTAATTCCTGGAATAAAAATTCTTGCCACTGCTCCTACTAGTGTTTTCCTTGTAACTGTTTTTACATAATTACTATCTTCTGCACCGAGATAATCTATTAATAAAGTGTTTATTCTCTCTTTACCATCCCATTTAAGACTATTTAAATATTCTTTAATGGGATGAAATGAATATTTTTCAAAAACTAGTGCTAAAGCATCAGCGCATTTTGCAGTACTTGAAATACTGTAATATTTCTCAATAAATTCTCTTAATCCACTGTCATCTGTATCATTCCAATCTGATCCATTATCTTTTTTTCTCCAAGGAAGTTGGCCAATAACTACAGCTCTGTTGGAAAATTCATTATAGGCTATCTTCCCTTTAAGCATTGGGTCATTTTCTATTATTAATAAAAAGTTACTAATAGTACTTCTTACCTTGCCTTGTTCTGTATAAGTAATTTTTTTTAGCCATTCTGTATCTACTTCCTCGGTTTCAACAATACCAAAATCCTCTTGAGCTTTTTCCATTCTTTCTTTTCCTAAAGTCTGCATTACTTTTTCATCAGAACTAGCAAACTCACTCATTCTAGTAAAAGATGGCATTCTATTGGCTGGAGTATCTGGTTTAGCCTCATCATCTAAATGGCCAAACTTATGAATTCTAACTAGGTCAAAGGAATTACATAGAGTATTACTAGCTGGATCCGTACCATGATGGCTATAGCTAAATTTATTCTCATATACTACAACCCCGCCTGTAGTGCTACCCTCTGCATATGTGTACCTGGTTTCATCTGCACCAGGTACATAAATATCATTTAAAAATTCTGCTATAGCTTCAGTTATTGTATAGGTTCTGCAGAATGCCCCTATAATACCTTTCTTTTCTAATGGGTCTTCTTGCTTTTTTATTGCATTATTTAATTTTGCCCTAGCTCTTGAGCTTTCTGGCCAATAACTTACATCTTGCCACCCAAAAGTATATCTAGCTAATATTTCATCAGGATTTAACCACGGTTCATCCTGGATTTTAAAGATATAATCTCCATCACTTGAAGTACTTGGCCAATACATTAATCTACTAGGTTCATAGGTTGTATCATCAAATTGATCTATTCCTAGATCACTAGCTATCATCCTAGATATAGCCTGATATTCATCTGGAAGTACTGGTCTACTTATAGGAATTACTAATCTTAATCTTTGATTATCTGCTGCATGAGTATGAGTTGAATACATAGCTACTGAAAAATCCCATAATAACTCTATGCTTGACCATATATCACCCTTAACGTAGTCTAAGTCCAAAGTTAATAATGTTCTATTCTGAACGTTCTCTGCTTTTCTACGACCATTCTTAAGGCCACCACCTACAAACCCACCTACATCTTTAATCATATCTTTTTCAGTTTTAGCCATTTTCTTATATTCCGCATAAGTTTCAGGTGTTCTTGTAGTATTACTCAGCTTTCCAACTAACTCTGACCATAAAATATTTTTATTTTTCCAATGAGTTTCTTTTCTACTCTTCCCAGTAGCTATAGCTATGGATCCGTCATATTTAATCTTAGGTTTATCTTCTGTTTTATAGGCCTCCAAGGTATCACCTCTTTTCTATATAAAAGAATGTTCTTTTTATTTAACCTTATTTCTCTACATATCTATCTACATTTTTTATCATAAAGGTTATGGATCCATCCCCATTATTTTGAATGCCAAATCTATTAATATCTTTATAAGCTTCTTCAGTTATACTAATTTCAATGTTACTATCTATTTTAAGTTTTAATCTACTAAGTCTTTTTTCTAAGTATTCTTTATCAACTTTTACCTTTTCAATATCATTAGCTTGCATATAAGCAATAAAATCTTTCTTACTTTCTTCAAAAGGTAAAATCTTTGAAGCAAAATTATATATGTCTATTTCTTCATTTTCTCTAAGTTCACTTTTAGCAAAACTTCTTATTTCCTCTGCCTTTACTGCATCTTCTTTTAAATTACTTCTTGTCCAATTCTCTACTGCATTCATAAAAACCCTTGTATTATCTCTATCATTATCAATTAATAGGCATTCAAGGAATTTTTCTGTAAAATAGTCAGTTCCGTATTCATCACTTTTCTTACTTTTAACTTTATCAAGTACCAAAAGATTATACTCTTGGTCATTACATATAGGTCTAATAAAAGCAGCCTTTTGAACTTTTTTAGTTGCTGGTAACCCCGTTGTTGTAGGTGTTATCCTAATTACTACATTATCATCAATAAAATCAATCTCATGCGCATATTGTTTAATATAATCAAGCTTAAGTATTCCTAACATAGGACCATATTCAGTACTAATAGATACAACAAATAAATTACAAGATGGTATATTAATATCAGATTTCATAAAACTAAATAAGTTATTAGCTATACAATTTGAAGCTCCAAGCAAATCACTCTGTCCATTTAAATACTCCTGGCTAGTTTCTCTTATCGCAGTACTACTTTCTTTAAATGTTGCATATTTTAAATCATTATCTTTGAGTATCCTTTCAGTATGACTTAAAATAAATTTATACACCTCATCAGTAAGGGCTATTTTATAATTATTTAATATAGGTTCATCTGAATTATTGTCTAGTACATGAAGTACTGCCTCATTTATTAAAATATCTCTAATTTTATCCATAATTTTTACACTCTCCTTATAAATTTTTATTTAAAATGTGTACTAATCTTCTGGTTCATAAATAGTAAACCAGTATGCCTCACTTTCATATGAAGTAGGTTTATTTATATTTATAAATTCATTTTTCTTATTAAATTCAGCTACATAATACCAATTCTTTTCATTACAAAATGCTGTTATTGTACTTACCGGACTAAGATTGTATTGCCCACTTCTTGTACATTTCCAACCATCTTTCAACATTTTATCTTTATGTTTATTCAGTTCCTTTTCTGATTCATATTTAAATACTTTAACTTCTAAATTTGCATTTAATATTTCTTTCACTTAAATTCTCCCTTATAATAATTTATTTGTATTACGAATTAATTACTTCTTATATTTATTACTAATGAACATACCAAGTTTAGTTTACACAACTTAGTAATAATAGCTGTATAATCTCCCTCATCTATCTTTTTCCTTTTATATTTAACTTTCTTTTCATCAAAATAATTTAGTATATGTTGATTTTTTTGCTCTCTTGTATCATATAAAATCATAAACTTTTCTTTAAGAAGTTTTTTAATTTCTGTATCTGTAAATTTATAATACATTCTTATCCTCCTGCCTTGATTATTTTGTTAATATATTTGAATTGTGACTTAACTAACTTTTTCTGATTTTCTATCTTTACATAATTCAGGCAAATTAGCCTCCACTAATGCTTTTGCAAATGGTGGCGGAACTGCATTTCCACACCTAGCAACTTGTTTAGTCTTTGGATATACACTTCCTTCATAATCATGGTCTATAATATAATCTTCCGGAAACCCTTGAGCTTTAAATAATTCATGTGGTTGCAACATTCTCATACCAATATCAATTATTCGATAATCTTCTCCCTTGATTGTTACAAGTCCGAATCTATCTTTAGTCGTAATTGTATGAAGCGGCTCATTTATTTTTTGTCCTATGTCAGTTCCGTAATACTTTAGCAAAAATGCAGTTACTAAATTAGATTTGTCTACTGTTGTAACTGTTGCTAATGGTTCATCTATTTTATGGCCTATTGAACTTTTAAACTGTCTTGTAATAAAGGCTGCAACTAATCCAAACCTATTAGAAGTATCTAGTGTGTGAATTGGATTATCTAAGCTTAATCCTCTAACTTCTCCTTGTTGAGTTTCAGAATGATAACTTGTTAAAAATGGAGCTATTAGTAAATGTTCTGCTTTAGTTGTTATAGTTGTAAGTGGTGAATCTAATTCATACTGTAACCCATCTTTTGCAAATCCAGTTTGGCCAATTCTTACTATAAATGGATTAGCGTTATCTATTACAAACTTTTGAAATCCTTTTGCTATTCTCCTAAGTGTATTTTCTGCTAGTGGTTTCTTTCTAGTAAAAATACTTGGACATGGAATACTCCAATCAATTATTTCTCCTGCTGTTCTCCAAGGTTTTAATAATCCGCATCTAACTTCTATTTGTTCTGGATCACCATGAGTTGACTCCGGCCACACTATAGGTTTACCATCACATCTTGCTATCATAAAAAATCTTTTTCTAGTAGTTGGTGCTCCATAATCACAGGCTCTTAGCTCTCTAAATTCCACCTTATATCCCTGTTTCTCTAGTGCCTTCTTGAATAACTCAAAAGTTTGTCCTTTCTTATTAGGGTCCGGATATAAGTTACCCTTACCATCTTCTTTTAATGGTCCCCAAGTTTTAAATTCCTCAACGTTTTCTAGCATTATCACCCTTGGTTTAACTAACTTCGCCCACTTTACAGCTACCCACGCCAATCCTCGTATATTTTTATCTACAGGTTTGCTTCCTTTAGCCTTACTAAAGTGTTTGCAATCTGGTGAAAACCAAGCTAATGCCACTTTATTATTCCCTACTGCTTCTACAGGATCTACTTCCCAAACTGATTCACAATAATGTTTTGTTGCAGGATGATTAGTCTTGTGCATTAATATAGCAGCTGGGTCATGATTTATCGCTATATCTACGCTTCTCCCAGTAGCTAGTTCTATACCCGTACTTGCTCCGCCTCCACCTGCGAAGTTATCTATAATTAACTCTTTCACTACTTCACCTCATTTACGTCGTATTTATTTCATATTCCGTCCTAATCCTTTTGGTAATAATTGCATTCATATCCATCAGCTTTCAAAGGTAATCCCGGAGCCCATTCTATAGGCTGGCCCATTAATTCATTTATTTCTTTAACTGTAGCCCTATCTTTTGGTATATCCAATACAACTTCATCATGCACATGCATTACTATGTCATATCCTGCTTTATCTACTCTAAACATAGCTTCTCTTAAACAATCTCTAGATGTAGCTTGTACTATATTCTCCACTAGTTTAGGGCCATAAGTATCTATTCTTTTCCATTGTTTAGACGTTTGTTCCATACCTTCATAGGTGATTTTATCCCCACTAAAGGTTTCATGCGGTTCTATCTTTGGCCTTATATAACTTAGCTTTCTTCCACTAGGCAATTGTATAAATAAAACTCCTGGATCATATATAAATTTAAGTCCGTATTGTAAGTTCACCGTAGTTCTTTCTCTTATAACTTTCTTAGCAGCCTTATCTACATCCCACCAAAATTTAGTTATATTAGGATTAGCATTTCTCCAACTTTTAACTAGTCCAGGAAGTTCTTCTTCTGGAATACTTTTTTTTCTATCCATTGAACTAAGAGCTCCAACACTTCCACCATACCCAAGTGCCAATTCTGCTATTTTTCCTTTTTGCCTTAACTCTGAACCCTTTTTTATACTTTCTATAGCTACCTTAAACATTTGACTAGCTGAAGCTTCATATATTTTCCCATGTGTACTAAAAACATCTAATCTCCATTGCTCTCCAGCAAACCAAGCGATAACCCTAGCTTCTATAGCACTAAAATCTGATACTATAAATCTATTACCTTCTCTAGGTATAAAAGCTGTTCTTATTAATTGGCTTAATGTATCTGGAACACTATCAAATAAAAATTCTACTTCCTGAAATTTCCCTCTCTAACAAAATTCCTAGCGTTGTCTAGATCCGGTAAATGATTTTGAGGTAGATTTTGAACTTGTACTAATCTTCCTGCCCATCTCCCCGTTCTATTAGCTCCATAGAATTGTAATAAACCTCTTACTCTACCATCTTTACATCTTGCATTTTGCATTGTGTCATATTTCTTAATAGAAGTTTTGGCCATTAGTTGCCTTAGTTCTAACATTTTTATAACTTCACTTTTATTTAAAGACGTAGCTTCTTCAATAAGTCCTGGAATACTTGTTTTAGTTAATGACTTTACCTCTCTTCCAAGCCTTTCGCCAATCCATTTTTTTATTTGTGTAGGACTGTTTGGATTTTCAAGCCCTGTAAGTTCAATAGCAGCCTTTGTTAATCTTTCAGTATAGTTTGTATCACATTCAATAGCCTGCTTTATAAGTATTAAATCAGTACCAATACCTCTATCATTTATGTGTTGGTCCAGCTGCCATAATTTTTGTTCTTCTACTTTAGTTTCATATCTATTTAATAAATTTCTTATTTCTCTTTCTACTTCAACATCTCGCTTACAGTATTCTTTAAAAGTTTCCCATTTCTCCATATCATGTTCTGGAAGATTCCTAGTTCTCTTACCATTGGTTTTAGTAGGTTTACAAGGCTTACAAAAATATTGTATTAAAGCCTTACCTTCTTTCATCTTTTGCTTATCCTCTTCAAACTTTAAAGCCTTACCAACCATATCCAAGGAACTTGGTAGCCCTAGTGTCAAAGCTTTTACCATGGTACATTCCCATTGTTCTGGTGGGCATAAAGCTGGGTATTGATTCTTTATTGAATTTCTTTCAAAGTTAGCATTAAATGCAGTTTTTATAATGTTTGGATCTGTTAAGGCATAAAATACATTTGAAGGTAATTTTTCTCCATTTGCTAAATCTACTATTTGTACTGGTTCATCATTAAAAGCATAAGCAAATAGTAATATTTCAAAATCAGGAGATTCACAATATTTATAAGCACCTGAAGTCTTTATATCCATACTGCTATATGTTTCAACATCTATAGATAAAGTATCAATAAATATCACCATCTTTCTTAGTAGTATTGGATTTATAAATTAACTTTCTTGCTATTTTCATCTACAGTTATTTTGAAACCACATTTACAAGTTCTTGTATAAGTATCATCTTCAACTATTATTCCACCTTCACCATTACCAATTTTATTATTTCCACATTTAGGACACTTCTCATATTTTTTCATTATAGGCATTAACTCTCTACTATTCATTTCTAAACCTCCAATCTTTGAATTGTGATATTATTTATATATTATTGGCTTATTATCTTTCTTTGGATATTGTTGTAAAATGATAGATTCCACATAACTTTTATTAATATATTTATTTACATATTCCATATGGTCTACAAAATCTTTCATAGTATAAGTTGCTTTGCTTTTATCATTACATTTTATAAATAATTTTTTCATTTCTATTACTCCATTCACAATAATTTTAAATTATGAATTATTGTATAATTAAGGGTGAGTTTAGTACTCACCCTATATGTTTTAGCCTAAAAAATCATCTTCTGCAGTTTCTACAGAATCAAAGTCGTCCTCTGCTCTTGTGAACCCTCCAAGAGGTTCACCCTCCTCTAACTTTTGAACATTACCTAGTCCACAAGCGATACCTTTATTACCACTTGCACTGTAAGCATAGAAATTAAGAGTAAGTCTTGCATAGCAGCCGCTATATACTTCTGTAGCATCTAATACAGGTTGTACATTTTTATCAACAATTCCAGGTTTATTTTTGCTGTTAGCATTTAAGTAATAACAATTTGCATAGGCTTCATCATCTGGCCTGTCTATATCACCATCATGAAGTGGAGTTTTTAAATTTAGCAGGTACTTTACCACCAAACTTACCCTTGCCCTGTTCTTTAGCTTCTGCTACTGCTTCTTTTATAGCTTTTAATGTCTCTATATCGGTCTTAGGAATTATTACACTTACGCCGTATTTTGGCTCTTGTCCCTCCATTGCTCTTGGTTCGAATAAATTTGCATAGCTTAATCTAACCTTTCCTGTAGTTACCTTTGTTCCTGTTCTTTTTGCTTTTATCATAATTAATCTCTCCTCTTTATAATAATTTTCTTTTTGTATCTCTTCTTCTACATAATCCATATACATAAGATACCTCTTTATTTAAAATCTGCTTCAGCAGAATTATAAACTGGTCTTTTATCTGTTATAGTTGCTAAAGTTGGTTTGCCTTGTGGCTTTATAATATAATCACCTAATAACTTAGTAACTTCTTTCTTACCTATAGCTTTTTCCATATTTGTAATTCCTGTAAGTTTTTTAGTATATATAATATCTTCTAAGAATCCTTGTCCTAAAAGTATTTTTCCTATTTTCTCTTCATCAGTCCACTTTCTATTACTTCTACCTTCAACAACCTTAAATCCGTCAAACTCCTCACCCTGTAAAGCTTGTTCTAATGCATATTCTTGTACATCTTTAGCCCAGTTAATGAGTTCGTCAGCTTTACCTAAAATAAAGGCTACATCATTATTGTCTAAGGTAATTGGCTCTTGAAAATCATACTTAGCTAGTTCCATATTCTTATCAGCTCTAGCCTTACATACTGCTTTAGCTCTACAGAATTTACAGTGATCTCCTGCGCAAAATTCTCCTTTACCTTCATAGGCTAATTTAGCTATAGGCTTTAATTCTTCTTCTGCCCACTTAAGTAATTCTTCTACTTTCATTTCATCTGTAGATATAGAATCTAACCTAGGTTGTATAATTGTCATTTTTATATTTTCTATATCATATAAAAAACTAAACTCTGCTATAGCTCCTAATGCATATAATCTCATTTGCTTATTATTAACTGCACTTACGGGAACACCCTTACCATACTTCAAATCACATATTTCCATTGTTCCATCTGCAATTATTACAAAGTCCCCAGTACCAAAACCATCAGGTACCCATTCACTAAAGTCTAATCTTTGTTCTATTTTAAATAATGCATCTGGTGTTTTAGCCTTAGCTTCTGCAACTTTCTCCATGCAGGTATCTACATAAACTTCTACATAATCTGGCATATCTTTTGTGAATAGTTTGTCCACCTCTATTTTCTTGAACTCAGAATTATATTTTCTTGTGGATATAAGTTCTAAGTTTTTCTTTAAACCTAACTCTCCTAATTCATGTGCTAAAGTTCCTTCCTTAGCAAATTCACTGCTTTTATTAGGGAAATCTTGTTCTAATCTTGCACTAGGTGGGCATGCAAGCCAACGACTTGCCCCACTAGCACTAAGTATTGCATGCTTTGTCATTATTCTTTTACCTCCCACACTTTTCCATTTAGAAATTCTAATACTCTTTGCCTTCCACTAGCTCCTACTGCTCTTAAAGCTAATTCCCATGGAATAAATTTATTCCACTCCTTAAATTTTATATAAGGTTTACCACTCTTAATAGCTTCCTCCAAAGTAAGCATTATAGTAAGGCCTCCACTTCTTTTATTACTGCAGCATAGTGTTCTTCTTTTAATTCAGGCAGTTTGCTAGCACCATATTTTGCGGTTATCTCCTTAGCTTCTTTCTGCTTACCTGCTTGTATTAACTTTGTAAATACTGCCCTTACCATTTCTTTTGTAATCTCAGTTTTAGGTTCTTCTACTGGTTTATCTTCTTTCTTAGTTTGTTCTGCTGGTGGATTTTTTTCTTTCTTAGTATCTTGCTTAGATGGTTCTACTGATTTAGATTCCTCCTTGTTAATATCTTTCTTAACTTCTTTTTTAGAAGTTTCCTTGATTACCTCTTTCTTTTCTGTAGATGCTTGTCCTACTTGTTTAGGCTCTATTTTCTGTATAGTATTAGCACCAAAAGTACTAATAAAATTTAATAACTCCTCATTTGAATTAAATTCTGCTGTAATTTTCATAATTATTTTTCCTCCTTAAATTTATTAACATTTTTATTAAATGGTTTAATCACCAAGAAAGTCATCTTCTAAATTGTTAGTTTGAATGCCCATTAATTCTTTTTGAATAATTTTTAAGCATTCTGTATCTTCAACTTTTACACCATATGTTTTTATTAAGCTTCCATTATTGAACGGGATAGATATTCTTAAGGTTCTAGTTAGGGGATAAAATTCCCAAGACACATCATGCTTTTGAGTAACTGTAATTTGAATAGCTCTAAATAAAATGTCCTGGATAATTTCATAGTTCTTGTCCATTAATCAGATCCTCCTAGAAACATTTTTGCTTCATGACTTTCTATATCAACTTTCTGAACTACCCATTTAGTAGCTTGCTCTACTCTGCTTTTAGTTTCTGAATACCTCTGAAATATTGCTATTGAATATGAATTATTAGCTTCTACAACTAATACATCACCATTTTTTAAGTCCTCTATGTCTGTTTTATAAGAATACTCTTGGTCAAAACTTCCTCTTGGAAACTTAACCATAGCTACTTTTTTATTCAATTGCTTATCTAGCCCCTTTCTGCTATACTGTATTTAGGTTTTTTAATTAAATTTATTGGTGGCTTAAGCCATCTCTTTTTTTATGCTGTTTACTTGAAATCTTAAATAATCTAGTGCCTCTATTTTTAATCTGGTAACATTACTTCTAGAACAACCAATTTTCCTGGCTATTTCTGCTTGAGTAAAACTTTGCATATAATACATTTCCATAATTTCTTTTAATTTTTCTGGTAAGCTGTCTATTAAAGTTTTTATTTCTATTTTTTCAAAGTTTAAATCATAATTTCCAATTGAATCTATATAGGCTATTTCATTATCAAGCCCATCTATAGCTGCATCTAAACTATACGGAACGATACCCTCTAACCTCTCTTTTCTATTTTTGCCGTACCATTTATCACTTTCTATCATTCTTAAGATTTGTCCATCTACGTAAGGATAAGCATATGTGCTAAACTTTATCCTCCTGCTACTATCAAATCTATTTGCGGCTTTCATAAGACCTAAACATCCTTCTTGAAATAAATCTTCATAGGAGTATTTATGCTTAAATTGTTTATATCTTTTATTTGTAATAAGATATACAATCCCCAAATGTTCCTCAGCATTAATCATTTATACCTCACCTCCTTATTACTTTATATCTGTTGCATTTCTTATAATTGCTGCAACAATATCGTTGAAAATATTTTGTTCTGGATTCTGTGCTTGTAAATTCTAGTCTGCCCCTTTTATGAAAGCATTTAATATAATATTTGCGACCATTGGATCTACTTTGAAAATCTGGGCATTTAGCTTTATTCAATTTTTTATCACCACCTAAATTATATTTACAAGTAATATAAATACTGGGGATAAAGCAACTATTATCCAACCTCCCTTATTTTCTTTTAGTAATCTTTTTAAATCTAGTATCATAAGAGCTGTAATTGCAATCAGACTATATAGTGTTGTTATAGCTTGTCCTATTGTGGTCAATATCTACACCCCCTCTGAGCTTTTACTCCATATTTAATAGCCATTTCCTTAACTATTGACACATAGCCCTCTATAAGCTTCTTATCATCACCTATTACACTTACTTTATTTAACCTATCTCTTTTGGACTTACACACTCCTTCATCTGCCATCCTTCTACGTTTATTAGTAAGTCTTTGCTCTAAATTCACGCCCATTCTTTTATCTAATAATGTATAAATCTCTTTCCTTACTTCTCTAATATATTCAAAACCACCAAAGTTTTGAGCTATCTTATTTATTAACTTAGTAGAATCTTCTTTCCATGATGTAGTATCTAATTTAACTACATCTCTAATAGCTTGTACCTCTTCTTTGGTCTCTTGTACTGCCACATTTAATTTCTTTTGTTCTAGTTCTGTAGTTGCTAATGCCTTAAATAAATTATTAAACATTTGTAATTCTGGACTAAGTTGATTTACTTCTACTTTATTTTCTTTTACCCTAAAGTAAGTTTCTTCTAAGTTGTCGAACTGCTCCCATGCCTTGTCCGTATCAAGTATTTTGCAATGGCGGTTCGCTCCTCGTTCTGTCCACAACATTAATTCACTTGCATATTTAAGGCTACTATCTTTAAGATAGTTGGCTTTAAATTCTTTTAGTTCTTCACCTATTAATCTAAAATAATGTTTACCCTTCTGGAATTTTTCTTTATTCCTAATAAACCCTTGCTGTATTCTTATAGGCTCAACACCGTAAACTTCTGCTAACTGCTCTGTTGTTAAAACTCTTTGTCCGTTAATTTCTACTGCTTTTATTTCTGTTGCCACAGGTTGTCCATTTTCTATAGTTAGATTTATCTTTTTCATTTTGTTACCCCCTTATAAAATTTGAAGTTAATTACTTTACATCTGTACGTATTTAAAATTATCATTTGTTCTTTTTAAATTCGTTTAAATCAGAACCTAAAACCTTTGCGGCATTGTTATCATATAGTTTTAGAAGTGCTTCGGTAAATATTTTTGAAGTATTTTCTCCCATTATTACTTCTACTTCTATATCATCTATATCCATATATACCTCCTGATACATTTTTACTCATATAATATGCATTAATCCTTAATTATGATAATTCTTTTTTTACCGTTTACAGTAATAGTTTTAATTTTCATTTTCCCCCTCCTCGAAAAAATATTTCCTCAATAGAACAATTTAATACACTTGCTATTTTTCTAGCTGTAGAAACCCTTGGCTCTCTAGTACCGTGCACTAATTCATGTGCGGTAGCTTGTCCTACATCAGCCTTCTTTGCTAGTTTATAAACTGACATCTTTTTAGTATCTAATATTTTTTTTAATTTGTTCATTTCGTATATCCCCCTTTCTGTAATTTCCGTATTCGGGATTACAATTGAATTATATTCCCTAATACGGCAACATTCAAATCCAACTATATCCTTTATTTTAAAAATATATTGTTTTTTCTTTAATTTACTTTAATTTACTTCAAAAATCTCTTTATTTTAATTCTGTAAAAGGAAATAGTTCTTGCATTTTTATTTCCTCTTGCGGAAATATGTCGTAAATATTTTGTTTACTATATTAAATAAAAATTGTATAATAGTTTTGTAAACGGAAATATATTAGGAGGTAGCAAAATGATTTCAATACTAGGACAAAATATAAAAAAAATAAGAACTGAAAAAGGACTAAGTGCATATAAATTAAGCAAACTTGCAAGAGTAGGAACAACAACTATAAGTGAAATTGAAAATGGTAAAAGGCAAAGCTTAAATTCTACTACTATAGAAAAAATAGCAAACGCATTAAATATATCTACTGATAGACTTATGGATGTAGAGGAGAATAAAGAATACATAGTAACTGATATAGAGCAAACTATTAAACTTATCTTAACAAGTGATGAATTAGTGCTTGATGATATTAAATTGAGTGATACTGAAAAGTTGCAAATAGAAAGTGTATTAAATGCTACATTTGCTATGATAAGAAGTCAAAGATCTAGAAATAGCTAGGAGGTAAATTAATGAAACGTATAGCTATATATTCTCGTAAATCCAGAGAAACAGATACTGGAGAGAGCATAAAAAATCAGATAGATATGTGCAAAACTTACTTTAATAGAGCAGACGATGACTGTTTATTTGAAATATTCCAGGATGAGGGTTTTAGCGGTGGTAACATTAATAGACCCTCCTTCCAAAGAATGTTAGAACTCGCGAAGCATAAACAATTTGATATTATTGCAGTTTATAAAGTTGATAGGGTTGCAAGAAACATAGTAGACTTTGTAAATATTTATGATGAATTAGAAAATCATGATGTTAAACTTGTATCTATAACAGAAGGATTTGACCCTAGTACACCAATTGGCAAAATGATGATGATGTTACTAGCTTCATTTGCTGAAATGGAACGAATGAATATAGCAGAAAGAGTTAGGGATAACATGAAGGGTCTTGCTAAAATAGGTCGTTGGAGTGGTGGAACTCCCCCCACTGGGTATAAAAATAAAACTATAATTAATGATAATGGTAAGAAAGAATCTTATTTAGAATTAATTCCCGAAAAGAAACAATTGATAATCTCTATATTTAGAAAAGCTGCAGACGGATATACTACATATCAAATTGGGAAAATGTTTAATATGTCGCCCAAGACAGTTTCAAACATTTTATGTAACCCAACTTATGTTAAATCTGATGAATTAAGTGCAAATTATTTGAAATCTATTGGCTATAGTGTTTTTGGTGAGTTAAATGGTAATGGTTATTTATCATATAACCGTCGTCCTAAGAAAAAAGGTAAAAAATTATCTAACGCCAAGGGAATGTTTACCGCCGTATCTAACCATGAGGCCCCAATTGATTCTAAAACATGGATAAAAGCTAATAATAACCTTAAAGATCGTGCTACGGAAGCCAAACCTAGAATTTCAAGTAATAGTTTTTTAGCCCACCTTGTAAAATGTTCCTGCGGTAGTGGTATGTATATACACACTGGTCACGCAAAAAAGGATGGTACTAAAAATCTGTATTTTGTATGCTCTAAAAAGAAAGGGGGAAGCAAATGCACCTCCAGGTGGTTGAGAGTAGATGGAGTAGAAAAAAAGGTTCTTAATGTTTTTAAAAAAATTTCCTTAAATCCCAAACTCTTAGAAAGCTATTTAAAACAAAAAAATAAACATGTAGACTATACAGAATCTATTAAAAATATAAAAAACAAATTAATAAAAATGACGAAAAAATAAATAGTCTAACTGATAAAATAATCTTTTTAAAAGGAGCCGCTATTGATATAGTATCTAAAAAAATAAACAACCTAGCTGATGAAAATTCAAGATTAAATGAACAATTATTAGCATTAGAAAGGAAAAAGATGTTTTCAGAAGTTGATGGGGAAAACATAAAGTTGCTTACGGTTAATATAAATCAGTTTCTACAAAACTTTGATAAAATAGATACTACTGAAAGGCAAATTTTTATTAAATCAATAATAAAAAAAATAGTTTGGAATAGCAATGCTAATAACAACAAAGGTAAGAAAGGTAAAATTAGCATTGAATTTTTAGAATAATTTTAGCATCAATTTTAGATGTACCGGATGTGCAGCAGCTATAAGCGCTAAAAAAGCTGGTGCTGATGTTAGTATATTTGAAAAGACCGATTTGCTTTTAGGATTAGGTAATGTTGGTGGAATAATGAGAAACAACGGAAGATTCACCGCAGCAGAGGAACTTATAGCTTTAGGTGCTGGCGATTTAATAAATATAACAGATGAAAACAGTAGACATAAAAACATAGATTTTCCTGGTCATAAACACGCATGGCTTTATGATGTAAATAAAATAGAACCTGCTGTAAAAAATCATATGAAAAATATGGGCATAGATATTCATCTTATCTCTAGAATAGTAGATGTAAAAAAAGAAGGAGATAAAATAAAAGGCATATATATTTCAGACGGAACTTACGTAGATGGTGATGTATTTATAGAAACTACTGGTTCTACAGGACCTATGGGCAATTGTTTAAGATATGGTAATGGATGTTCTATGTGTGTTCTAAGATGTCCTGCCTTTGGCCCTAGGGTAAGCTTAACTTCAAGAGCTGGAGTAGATGATTTCCAAGGAGAAAGAGAAGATGATTTACTAGGAGCCTTTAGTGGTTCCTGTAAACTAGCTAAAGAAACTATGTCTGATGAATTGGTAAAAGAACTTGATGAAACTGGAGTATTGGTTCTAAAGGTTCCAAAGGAAGATATAAACTTAGATAAATTAAAAATGAAGGTCTGTCAACAATACGCTCTAAAAGAATTTGCAGAAAATATCATAATACTAGATACTGGTCATGCAAAATTAATGACTTCTTATTATCCTTTAGATAAACTAAGAAAACTAAAGGGATTGGAAAAAGTAAAATATATAGATCCTTATGCAGGTGGAAAAGGGAATTCTATAAGATATTTATCTGTAGCTCCAAGAACAGATGATATGAAAGTAAAAGGCCTAGAAAATCTTTTTGTTGGTGGAGAAAAATCAGGGCTGTTTGTGGGTCACACTGAAGCCATAACCACAGGAAGTTTAGCTGGACACAATGCTGTAAGATATTGTTTAGGTATGCCAATGTTAATTCTCCCAAGAAGTATGGCTTTAGGAGATTTAATAGCCTACGCAAATCATAAGCTTTATTCAAAGGAAGGTAGAAAAAATAGATATACCTTTGCCGGTGCAGAATATTTTAAGAGAATGGTTGAAGAAAACTTGTATACTACAGATAAAGAAGGGATAAATAAAAGAATTTCAAAATTAAACTTGGAAAATGCTTTAGCTCAAAGATTGGTATAAAAATTTAGGAGCCAAGATTATGGCTCCTTTTAAAATTTTTATACTAAATATTATACATTTATTTCTGCTTTTTCTCCTAGCATTGCTTTGTTCTGTTCTAATATTGGATTTACTACTTCTTCTATAAAATCTACTACTTGACCTTCTGCTCTTCCTGTAAATTTTTTAGGATCTATTAAAGCTAATATTTCTTCTTTGGTTAATTCAAAGGATTCATCTTCTATTATTCTTTCTATTAGATCATTAGATAATCCTTCCTGCTTAACTCTTCTTGCAGCTTCCATAGAATGAGTTCTTATAACTTCGTGAAGCTCTTGTCTGTCTCCACCCTTTTTAACTGCTTCCATCATTATATTTTCTGTGGCCATAAATGGAAGTTCTGTTTTCACATGACTTTCTATAACTTTTTCGTATACTACCATATTCTCTGATATATTCATATATAGTTTAAGCACTCCATCTAAAGCTAGGAAAGCTTCTGCTATAGATATTCTCTTATTAGCAGAATCATCTAGTGTTCTTTCAAACCATTGTGTAGAAGAGGTTATAGCTGGATTTAAAGCATCTACTATAACGTATCTTGCTAAGGCTCCCATTCTTTCTGATCTCATTGGATTTCTCTTATAGGCCATAGCTGATGAACCTATTTGATTTTTTTCGAAGGGTTCTTCCATCTCCTTCATACTTTGAAGTAATCTTAAGTCATTGCTAAATTTGTATGCACTTTGAGCTATTTCTGATAATGTATTTAATATAGTTGAATCAACTTTTCTCGGATAGGTTTGACCTGTTACCATAAATTCCTTTGGGAAGCCCATCTTTTCTGCTACCTTTTTATCTAAAGCTTTTACTTTACTTTCATCTCCATCAAACAATTCCATAAAGCTGGCTTGGGTACCTGTAGTTCCTTTAACCCCTCTAAATCTTAAAGTATCTATAACAAATTCTAATTGTTCTAAATCTAATACTAAATCTTGCATCCAAAGGGTTGCTCTTTTACCTACTGTAGTAAGTTGAGCCGGTTGAAAATGAGTAAAGCCTAAAGCTGGTACATGCTTATATTCTAAGGCAAACTTTTTCAAATTATTTATAACATTTATAATTTTCTTCTTTATTAAAATCATAGCTTCTTTCATTATAATTAAATCTGTGTTATCACCTACATAACAACTAGTAGCTCCTAAATGTATTATACCCTTTGCTTTAGGGCATTGAACGCCATAAGCATATACATGACTCATAACATCATGTCGAACTTCCTTTTCTCTCTCTTCTGCTACTTCATAATTTATATCATCTATATACTTTTTTAATTCATTTATTTGCTCTTCTGTAATGTTAAGACCTAATTCCTTTTCGCTTTCTGCTAGGGCCACCCATAATTTTCTCCAAGTTTTAAATTTCATTTCTTCTGAAAATAAATAGCTCATTTCTTTAGATGAATATCTTTTGTTTAAGGGATTATTATAAATATCTCTCATTACTCCATCTCCTCTATGCGTACAATATGTATATATTTATTTTATTTATTCATATTATAACATATATTGCAGTATTTTTTCAATTTTATATTCGTATATTTTCTTAATATGCTATTTTAAATTCTTTATTATAATCGGGTTTTAACTTGGTAATTATTCTTTAAATAAAAATATTTTGTTCTATTTTTTTATACTGCTAATATAATTTATTAAGATGTATTTAAAGGAGTGGATTTCATGTATAAAGTAAGTCTTATAGATAAAATTTCTTTTATATTGGTGACCGTTGGAGCTATTAATTGGGGACTTATAGGTTTATGTAATTTTAATCTTATTGGTGTATTATTTGGGGAACCTGCAAATTTTGTAGGAAGATTAATTTATATATTAATCGGAGCGGCTGGAATTAACATGGTACTATTTCTTATTAAAACAAAAGGATCTTTAAAACATAAATAAAAGGCTCCCCAAAAGAGCCCTTAATTTTTATTCTAATGTATTTATTAATTTTGAGATTTCTTCTATAGCTAGGGTTTCATCATCACCAGAAGCTATTAATTTTATTTTTGCTCCACTTGTAACTCCTAATGAAAGAACTCCTATAAGACTCTTTATGTTGGCTTTTTTACCATTAAATTCAATAGATAAATCTGATTTAAAGGATGAAGCCTTTTTTACTAATAAAGTTGCTGGTCTTGCATGTAAACCAGTTGAACTGTTTACAGTTAATTCTCTTTCTAACATTTTATCCACCTCTTTTATAATCTATCTGTTTCTTAAAAAACATATACGTAATATTATACCATTTTTTTCTACAGATTTCAACAGTTTTTATAAACCATTACATGATATTATTAATCCAATTTTTTCATGAATTTTTCTATTCTATCTAATCCTCTTTCTATATTCTCCATAGATGTAGCATAGGATAATCTTATAAAATTATCATCACCAAAGGCTATACCTGGCACTACCGCTACCTTTTCTTCTTCTAATAAAATTTTTGAAAAACTTATAGAATCCTTTATGGTATTGCCTTTTATAGTTTTTCCCATAGCTTTTGATATATTAACCATTACATAAAAAGCTCCTTTAGGATTTATAGATGACAAATTTCCTATAGAATTTACTTTATTCACCATATAATCTCTTCTCTTTTTAAACTCCACTATCATATTTTTAACCTGAGTTTTATCTCCTTTAAGAGCTTCTAAGGATGCATATTGAGCTATAGAGTTTGGATTAGATGTGGTATGGCTTTGTATATTGCTCATCACTTTTATTATATCCAAAGGACCCGCTGCATATCCTATTCTCCAACCGGTCATGGAATAGGATTTAGACATACCATTTATTACTACAGTCCTTTTAAAAGCATCCTCTGATAAGCTTGCTATACTTATATGATTTTCTTCTCCATACATTAACATTTCGTATATTTCATCTGCTATTATTAATAAATCATGTTTTTTGGCAAAAATAGCTAAGGCTTCTAAATCTTCTTTGCTATATACTGTTCCTGTAGGATTGTTAGGGCTGTTTATTATGATGGCCTTTGTTTTATCTGTTACTTTATTTTCTAATTCTTCTATTTCATATTTAAAATGATTTTCTTCTTTTGTATCTACAAAAATAGGTACTCCACCATATAGTTTTATAAGTTCTGGATAGCTTACCCAATAAGGTTTAGCTATTAAAATCTCATCTCCTTCATTTAATATGGCTTCAAATAAATTTGAAAGACATTGCTTTGCTCCATTACTTACTATTATTTCACTAGTTTCATAGTTTAAACCATTGTCTTTTTTAAATTTATCTACTATAGACTGTTTTAATTCTAATATACCTGAAGCTGCTGTATATTTAGTATATCCTTCTTCTATGGCTAACATAGCTGCTTTTTGTATATTCTCCGGTGTGTTAAAATCCGGCTCTCCCGCTCCAAAACCTATAACATCTATACCTTCTGCTTTCATTTTTTTAGCTTTTGCAGTTATTTCTAATGTTAAGGATGGTTGTATTTCTATTGCTTTTTTAGATAATTTCATATTTTTGCCTCCACTTTTTATTCTAAATTTAAAATAAATTATTACTAAATTTATTGCTCATAAGTTTAATTTTAATAATTACTTAAAATAGCTTCTAGTATAAGAATTTCTTTATAATTATGATTAACTTTATAACATATTAATCTAGCTTCTAGCTACTAGTATTACTCCTATCATTATAAATGCAACTCCTAATATTCTTATAGGGGTTATATTTTCTTTAAAGAAAAAGTAAGAGAATATCATTACTAATACATAGCCTAAACTTACCATTGGATATGCATAGCTTAATTCTACTTTACTCAATACTTTTATCCAAAGTAAAAAGCTAACTCCATAGGATATTATACCTGCCATTACTGGCATATTTTTTAATATAGATACTATACTAGGTAAGAAGTGTGCTGGTGAAAAATTTAATGTTAAATTAACTGCTCCATATTTCACCAATATTTGTCCTAATGCTCCTAGAAAAACTGATGTCAATATTAAATATATCATCTTTTTAACTCCTTAAATAAAAGTATTCCATGTTTAATAAAATAAACCCAAAAGTATATAATTATAAATATTAATGGGAAAGCATATCTGCCTTGCCCTTCAGTAATAAAGTATACTGAAGTAAACATATGAAATAGAATTGTAGAATACAAATTAAATTTATTTAGATTTTCTGTTCTTCTTTTTATTATTTGTATAAGTATAAAAATGCTGTAAATTAATACATATATAATAGCTGGAATGAAAACCATATTTCTTATACAGTTTGTTGCTGCAAATAATTTAAACTTAACAGTATCATTCATAGTTACCCCATGAATGCTATATGCTACGTCATCTCCCACCATATATGTATTAAAGAGTCTCTTAAAACCTAATATTACAAATTCCTTTGGATGAGATTTTATCCATTCTTTAGCTGCTTTATTAAGCATTTTATTTTTTTGTGTATAAGAAGCTTTTTTATATTCCTCTGTTTCTGCTAATGAGTTTTCTACATCATATATACTCATCCATCTTCCCATATTGTTTTGAGAATTATTATTTATATAAAGTACTATTCCTCCGTTATTTGATACAAAGGTACGTTCTCCATTATATTTTGTATTTCTATAAATCCAAGGACTTATAGTAATTAAAGCTACTACAGCTATTATTATGGCTGATTTTAAAGATTTTAGAAAAGATTTTTCTTTTAATAATTCAACTAAAAATATAGCAAAGGCATATAATAAGAAAAATGGCTTTACCATGGTGGTCGCTCCTACTAATACTCCTAAAATTACATATTTATATTTTATATCACTAAAGTATAAATATGTTAATAATAAAAGTAATGTAGTAAATAATATTTCTGTACCTAAAACACTGTTAAAGAATATATTATTGGGAAATAACACGAATAGAGTAAATACTATTTTTCTATTTCGTTCTGTAATTTTTATTTTTCTTAATATTCCTAAGAATAATACTTGTCCAAAAAAAGTTAGTACTAAATTAAATATTTTACCTAAGGCTAGACTAGCTCCAAAAAGCTTAAATAGTCCTCCTAAAACTATACTGTAACCTACGGAGGTATAAGTATCTCCCCACTCACCTCCATTAGCTATACTAACTGCTAAATTATAATAATATTCAAAATCTGAAAAAGGCTTTGTATCTACAAATATCACCCAAAGAATACAAAGAAGCATAGATAAACCTATTATTATTTTATAATAATTTGTTTTACTATAATTACTGTCTTTATTTTCATAACCACTTAAATAATTAAATTCCATTACATTTATACACCATCCTTAAAGTTTAAAATATATTATAACCACTACTGATATTACCCACAATACCATATTCACCAAAAAAGGTTTATCCTTTCCAAAAACATCCTCTGGCTTTCCCCCTAGATTATGGTTGTTCATTAAATATTGATATCTAAATATTCCGTATAGTACAAAAGGTATGGTATACATCATCCTTTTACTTTGTACTGAACTAAAAGTATATATACAATAGGATATTAATATAGATGGAGTTACTATAGTTAGCATATTATCTATAAGTTCTACAGAATATTCTTCTAATATCTTTCTATGGCTCCCCCTATTATCTTTTAAAGTTATTATTTCACTCTTTCTTTTGTTTAAAGCTAAGAATAGGGATAAAAGTATGGTACATAAAAACAACCAAGGTGATACAGAAACCTTGGTAGCTAAACTGCCGCTTTCCATTCTTAGTACAAATCCAAAGGTTATCACCATTACATCTAATATAACTACATTTTTTAACTTAAAACAATAAAATATGTTCATTACAATATATAATAAATATATATACATAATCTTATAATCTACAAATTTATAGGAACAAAATAATACTGTGAAAAGTATTACTATATTCATAATTATAGCTGTAGATTTAGATACTCTTCCACTTGGGAGAGGTCTGTTTTTCTTTTCAGGATGTTTTTTATCCTTTTCTAGATCTACTATATCATTAAGTATATATATTGTAGACGAAGTTAAACAAAATAATATAAATGTTATTATATTATTTTTTAATATGATTTCATTTGTTAGATTACCTGAAAATATTATTGCTGCAAAGACAAAAAAATTCTTTATCCATTGTTTTGGTCTCATTAATGCTATAATTCCTTTTATATCCATCTTTCCCTCCTAATAATACTATATATATTTTTAGGTTTTATTTAATAAATAAAACATATTTATAGTTATAAAAATATAACTAACATATAATTTATCACACTTTTGAAATAAATTAAAGGACTTGAATATAAATTCAAGCCCTTTCGTTTTATGTTTTTAATTATTATCTTGGCTGAACTATTAATTTAATAGCAGTTCTTTCTTCGCCATCGATTTCTATATCAGTAAAGGCTGGTATACAAATTAAATCGATTCCACTTGGAGCCACAAAACCTCTTGCTATAGCTACTGCCTTAATTGCTTGATTAATAGCCCCTGCTCCTATTGCTTGTATTTCAGCAGCACCTCTTTCTCTTAGTACCCCTGCTAAAGCACCTGCTACTGAATTTGGACTTGATTTTGCTGAAACTTTTAATACTTCCATAAGTAAACCTCCTATTTTAACTTTAATTTAATAGTCTTACTTACATATATCTATTCTACAAAAAATTAAAAATTCCTTTTAAATTTTGTAAATTTTAGCAACTTATAAAACTTAAAAGGAATTTATTTTATAATCTAATTATTTAGCATATTCAATGGCACGGGTTTCTCTGATGACATTAACCTTTATTTGACCAGGATATTCAAGTTCACTTTCTATCTGTTTAACTATATTCCTAGCCATTTCAATACAGCCAGTATCATCAAGCACCTCTGGTTTAACCATAATTCTTATTTCTCTTCCCGCTTGAATTGCATATGACTTTTCTACACCTTCACACTCATTTGCAATTTCTTCTAACTTTTCTAATCTCTTTATATAAGCTTCTAAAGTTTCTCTTCTAGCTCCTGGTCTTGCTGCAGATATAGCATCTGCCGCTTGAACAAGTATTGCTTCTAGAGATTGTGGTTCCATATCACCATGATGAGCTCCTATAGCATTTACTACTAATGCGGATTCACGGTATTTTTTAGCTATCTCAGATCCTATAATTGCGTGTGGTCCCTCAACTTCATGGTCTACTGCCTTACCTATATCATGTAATAAACCTACTCTTTTTGCTAAAGTTGGGTCTATTCCAAGTTCGGAGGCCATAAGACCTGCTAAATGTGAAACTTCTATAGAATGCTTTAATACATTTTGACCATAACTTGTTCTGTACTTTAATCTACCTAATAATCTAATCAATTCAATATGAAGACCATGAATACCTGTTTCAAAGGTAGCCTGTTCTCCTTCTTCTTTAATACTAACTTCAACTTCTTTCTTAGCTTTCTCAACCATTTCTTCAATTCTAGCTGGATGGATTCTTCCATCAACTATTAATTTTTCTAACGCAATTCTTGCAACTTCTCTTCTAATTGGATCGAAACCAGATAATATAACTGCTTCTGGTGTATCATCTATTATTAGATCAACCCCTGTAAGCGTTTCTAATGTTCTTATATTTCTTCCTTCTCTTCCAATTATTCTTCCTTTCATTTCATCGTTAGGAAGATTAACTACATGTACTGTAGTTTCTGCTACATGATCTGCAGCACATCTTTGGATGGCATATGTAATGACTTCTCTTGCTCTTTTGTCTGCTTCTTCCTTAGCTTTAGTTTCTATTTCTTTTATCATTACTGCAGTTTCATGTTTTACTTCTTTTCTAACCTGTTCTAATAAAAATTCTTTAGCCTGTTCTGTTGTAAGTCCTGAAATTCTCTCTAATTCTGTTCTTTGCTTTTCGTGAAGTTCCTCCATATGTGCTTCCACATCTTCTATTTTTTGCTGCTTTTTGTTTAAAGCTTCTTCTTTGTTTTCAAGGGCCTCACTCTTTTTATCTAAAGCTTCTTCTTTTTGAATTATTCTTCTTTCAAGACGCTGAACTTCATTACGTCTTTCTCTATTTTCTCTTTCAACCTCTGCTCTTAATTTATGAGCTTCTTCTTTAGCCTCTAATATAGCTTCTTTCTTTTTTGCCTCTGCATCTCTTTCAGCCTCTTCTTTTAATCTTCTAGCTTCTTTGGATGCCTCTGATAATTTTTCTTTAGCTTTTTTATCAACTACATATAAACCTAAAATTACACAAATTATTATAATAACCACTGCGATTATTATATATTTCGTTGGACCCATAAAACACCTCCTTTGCTTTTTCTGCTTGCCATATATAAGTAAATATGAAGCTTAGAAAAGGTGTCATATTATTCAATTGGATCATGTATGCTAAACCAGATTTTGTTTTCATTTTATATTAAAAAAATGCCATTGTCAAGTTTATATAGCATTATCTGCCTCCCTTATTCATATTATTTATAATTTTTATATTTATATATTTTTTCATAAAAAAAGTAGGATAAACTCCTACTTTTATCCTTCCTTATTGTCTTGTTTTTTATTCTCTATATTTAAGTTTTTTGCATCAGCAACTGGTAAATCATGTTTTTTTCTTATAGTATTTTCTATCTCTAAGGCTATATTCATATTATCTTTTAAAAATTGTTTTGCATTTTCTCTTCCTTGTCCTAATCTTGTATCTTTATAAGAGAACCAAGAACCACTTTTGTCAACTAGCTCTTCTCTAACACCTACATCTAATATATTTCCTACCTTTGATATTCCTTCATTATACATTATATCAAATTCTGCCATTTTAAATGGAGGAGCTACTTTATTTTTATTTATTTTCACTCTTGTTCTATTACCTAAGATTTGATCACCTTGTTTTATAGAATCTATTCTTCTTACATCTAGTCTAACAGAAGAATAGAATTTTAATGCTCTTCCACCAGGAGTTGTTTCTGGATTTCCAAACATTATACCAACCTTTTCTCTTAATTGGTTTATAAATATAGCTACACACTTAGATTTATTTATAGATCCTGCTAATTTTCTTAGGGCTTGAGACATAAGTCTTGCTTGAAGACCTACATGTGAGTCTCCCATTTCTCCTTCTATTTCTGCCCTAGGAACTAAAGCTGCTACGGAGTCTACAACTATAACATCTACTGCTCCTGATCTTACTAAAGCTTCTGTTATCTCTAAAGCCTGTTCTCCTGTATCTGGTTGAGAAACTATTAGGTTATCTATATCAACACCTAAATTTCTAGCATAAGATGGATCTAAAGCATGTTCTGCATCTATAAAAGCTGCTGCCCCACCTATTTTTTGCGCTTCTGCTAATATATGAAGTGCAACAGTGGTTTTACCTGAGGACTCTGGTCCAAATATTTCTATTATCCTTCCTCTAGGAACTCCCCCTATACCTAATGCTATATCTAAATCTAAGCTTCCTGTGGATATGGATTCTACGTTTAATATACTATCCTCTCCAAGTTTCATTATAGAACCTTTTCCAAATTGTTTCTCTATTTGTCCCATAGCTGCTTCTATGGCTTTTAATTTTTCTGGATTAACTTTATTTGCCAAAACTGACACCAACCTTTCCTTACCGAACTTATGTTCTTAATATAATTATATACTATTTTTTTACTAGGGTCAACTTAATATAATATAAATAAAAGCCCCCTACAGGAACTTTTATTTAAATTATTGACAATATATTTTTTTATAAACCTACTTATCATGGCTCATTACATCTTTATTTTTAACAAAGTAATCTACACCAGATACTATAGTTATTATTATAGCTAATGCCATAGTAATATTGGTTATATTCGCTATAATATTTATATAATTTACAGCCCAATTTCCTAATATATATATTCCCTCTTTGTAATTTAGATTTACAAGAGCAAATATTATAGCTACAATTTGTATTACGGTTTTAGCCTTTCCCCATTTACTAGCAGCAATTACTACCCCCTCTGCAGAAGCCACACTTCTAAGTCCTGTTACCGCAAATTCTCTGGCTATAATTATTATACAGGCCCATCCAGGTACTATTTGAAAATCTACTAAAGATATTAATGCTGCTGTTACTAACATTTTATCTGCTAGAGGATCCATTATTTTACCAAATCTAGTAACTTGATTTCTACTTCTGGCTATGTACCCATCTAATTTATCTGTAGCTGAAGCTATTACGAAAACTGCAGTAGCTATTACTGTACCATAGGGTATGTTTTTTACTGATATAAATATAAGAAATATTGGAACTAAAAAAATTCTTAATATAGTTAGTTTATTTGCTAAGTTCATTATAAACAACTCCTATTAAATCATATTCTAAACTATGAGTTACCTTCACCTTTATTATATCACCAATTTTTACGTTTTCATCCTTTTCAAAGTAAATTTCTCCATCTATCTCCGGTGACATTTCATAATTTCTCCCATAATACATATCTTCTTTGGTACCTTCTACTATGACTTCATATATTTTACCTATTTTCTCTTTATTTATGTCTTTAGATATACTTTGCTGAAGTATCATTATTTCTTCTTCTCTTTTTTCTTTTATTTCTTCATCTATTTGTTCCTCCATAAGAGCTGCTGACGTTCCTTCTTCCTTTGAATATTTAAATACACCTAATTTATCTAATTTTACATCTGAAACAAATTCTTTAAGTTCACTAAACTCTCCTTCTGTTTCCCCTGGAAATCCGACTATTAATGAAGTCCTTAAAGTAATACCCTCTATTTCTTTTCTTAATTTTTTTATTATATCTATGATAGTTTCCTTTGTAGTTTTTCTTCCCATTCTTTTTAAAACAGAATTACTTATCTGCTGTATAGGCAAATCTAAATATTTACATACCTTATCATTATTTTTAATCTCTTCTATAAGTTCCTTAGTTATTTCCTCTGGGTAACAGTATAATAATCTTATCCACTTTACACCTTCAACTTTAGAAATATCTCTTAGAAGCTCATGTAAAACTTTTTTGCCATATATATCTATTCCATACATGGTTGTATCTTGAGCTATCAATATTATTTCTTTAACTCCTTGTTTAGCTAAATTTTCTACTTCCTTTAATATATTTTCTTTTTTTCTACTTCTATACTTCCCTCTTATGCGTGGTATGGCACAGTAAGTACAAAAATTATTACATCCTTCTGCTATTCTCACATAGGCTGTGTATGTTGGCGTAGTTAATATTCTATTTCCCTCATTTATTTTTGTATCACTATATTTATGATAAAAACTTTTTTCTCCTGATTTCAAAAAGACTTTTATACTTTCAAGTAACTTATCATAATCATTTACCCCTAACATAATATCCATTTCTGGGATAAGTTCTTTAAGTTCCCCTTTATATCTTTGAGTCAAACATCCTGTAACTACTAATACTTTGCAATTATGAGTTTTTTTATAGGAAGCCATTTGTAAAATGGTATTTATAGATTCTTCCTTAGCGGTTTCAATAAATCCACAGGTATTTACTATAATTACCTGTGCTTCTTTAGGATTTTTTACTAGTTCTGCTTCTTCATTTAATTTGTATAGCATAAGTTCTGAATCAATTCTATTTTTATCACAACCTAAGCTAACTAATGCTACTTTAATTTTTTCCACCTGTTCCCCTCCTACATTTTTTATGTCACAAGAAACATTTTAAATCTACTTAAGAAATTTTACAAGTATTAAGTAACTTGAATTTTAAAAGTATTTACATATTTCCTCGGAAATATTTTCCGTAGGTTTCATTGTTTTTATCAATTATTACTTGTCTTGGTTTATTACCATCTCTTCCGGAAATTATTCCCTTAGCTTCTAGCTGTTCTATTATTCTTGCTGCCCTATTATATCCTATTCTAAGTTTTCTTTGAATTAGTGATGTGGATACCTCTCCTAATTGTATACATATTCTTATAGCCTCTTCTAAAAGCTCATCCTCATCCCCGGCTTCTACATTTACAGCTGTATCTATTTGATCTATTATTTCTTCTCTATATTCTGCTTCTCCTTGCTCATCCTTTATACATGAAACTACCTTTTCCACTTCACTTTCAGATATAAAAGCCCCTTGTATTCTAGTAGGTTTTGGAGATCCTGTTGGATAAAATAACATATCTCCTTTTCCTAAAAGTTTTTCTGCTCCTGACATATCTAATATGGTTCTAGAATCTATAGAACTAGATACTGCAAAGGATATTCTAGAAGGTATATTTGCCTTTATTATCCCTGTTATAACATCTACAGAAGGTCTTTGTGTTGCTATAACTAAATGCATGCCTGCTGCTCTAGCCATTTGAGCTAATCTACTTATGTAGTCTTCTATATCATTTGGACAAACCATCATTAAATCTGCAAGCTCATCTATTATTATTACCACATAAGGTAATTTATTTTCTATTTTACCCTGGTCATATAAATTATTATATCCCTCTATATTTCTTACACTATTTTCTGCAAATAAAGAATATCTCTTTGTCATTTCATTTACTGCCCAATGAAGAGCTCCTGCCGCTTTTTTAGGATCTGTAACTACTGGAATCAATAAATGAGGTATACCATTATATATGCTAAGTTCTACTACCTTTGGATCCACCATAAGTAATTTTACATTTTCTGGAGAATATTTATATAAAATACTTATTATTAATGTATTTATACATACACTTTTTCCTGAACCTGTAGCTCCTGCTATTAATAGGTGAGGCATTTTTGATAAATCTGATACTACACAACTACCACTTATATCCTTTCCCAAAGCAAAAGCTAGTCCATCATCAAATTTCTGAAATTCATCTCCTTCTATAACTTCTCTTAAATATACCGGTGTTAGGGATTTGTTTGGCACTTCTATACCTACTGCAGATTTTCCTGGTATAGGAGCCTCTATTCTAACTCCTGAAGCTGCTAAATTTAGCGCTATATCGTCTGCTAAATTTACTATTTTACTTACTTTAACTCCCGCATTAGGTTGAAGTTCAAACCTTGTAACTGAAGGTCCTCTACTTACTTGCATAACTTTAGCTTCTACACCAAAACTACTTAAAGTTTCCTCTAACTTATTTGCGTTATTTATAAGTTCTTTTTTATCTTGTTTATTTAGTTTTGACTGAATATTTTGTTTTAAAAGTTCTAAGGTTGGATAGTTATATTCTATTTTTACATTGTTTCCCCCTTCATTTATATTTTTACTAAGCTCTTCTTTTATAGCCTCTTCCCCAGTATCTTCTTTAGATTTTTCTATATTTTCACTAACAGAATTATCCACGATATTTAGTGGACCTTCCTTTATTTCTGAGTTTTTCATAAAATCTAATATTTTGATTTTGTCTTTAATATTTCTAGTTAAACCTTCATCTTTTTCTAAGTCCGGAGCTAATTCTTTTTCTATACCGTCTATGTCTTCTTTATCTTCTATAGATTTTTCTTTAACTTTTTTATTTTTTATACTTCTTTTTACCTGTAAAGTCTGTAGTATAGTACCTAAGGATACTTGAAATATTAATATAAAACTTATTATATAAACACATATAAACAATATGTAACATCCTATAGTTCCAAACAGTTTATATAAAGGAACATCTATTAGATAAGAAATTATACCACCATGAATCATTGTATCTTCTCTATAAAATTTTGATATGCCAAGCATTATATCTTCTGTGCCATAACTTTTTAAAAGTATCATTTGTAAAAATAAAAGTGTATTTATAGAGAAAAGAACTATTCCATAAAATTTAGAGTTCAAATTTATTTTATTCTTCTTTCCTATAAAGCAACATCCTGTGAATATTATTAGTATTGGAAATACTAAAGATCCTAAACCTAATACAGCTATAAGTACTTTTTTTATGAAACTCCCAACTATTCCAGAGGCAGAAGGGGAAAACACACTAAAAAGTACAAAAATTCCCATACTTATTAGAATTATACCTGTTATATCATTATTCTTTTTTTCTGTTTTATTAGATTTAGTTCTTTTCTTTGCCATACTTTTAATTCACCTTCCAACTAGTAATGTTTAATTTAAGCTACATTTATAGATTCTACATTGAACTTTTATATCCTTTTATATTAATTAATGCATACCTACTTTGTTAAAATAAATATTTAGCTATATATAACTAAATAAACATAGCTTGTACATTTTATAATTGTATAAAATAATTTAAATACTATATTAAATAAGACATTAAAGTAGAGGGTGTCTCAAAATAAAAACAGCCTTAATTTTAATATAGTAAATATAAATAATACATGTAATAAACATATAAATGAGCTTTAGTAGTTCTTAATTTGACGGAATTAAAAATTTTTGTAATTCCTCACAGGACGTGAGGAGCCAATAGTAAAGCCAAGGAAGGCGCCTCTACTGGGTAAAAAATTTTTAATGGAGTCAAATTTAGAACTGCTTAGCAAAATGAATTGCTTTATGGATGTATTATTTATATTTACGGTTTTAAAATTAAGGCTATTTTGAGACATCCTCTTTTTGTTTTTCATCTATTAAATTATTTAATTTATCTAAAGCCTCTTTTACTCCACCTACTTCATTTATAATTCCTGATTCTACCGCTTGTTTTCCTATAAGTATAGTTCCCATATCATTTAACAATTCATCACTTTGCAACATAAATTCTTTTAACTTTTCCTTGCTTATTTTAGAGGTTCTAACTATAAATTCTATTATTCTCTCTTGCATTTTATTAAAATATTCAAAGGTTTGAGGAACTCCTATTATTAGCCCGTTCATTCTTATAGGATGAACTATCATTGTGGCTGTAGGAGATATAAAAGAATAATCCGCTGACGTAGCTAAGGGTACTCCTATAGAATGTCCTCCTCCTATTACTAAAGATACTGTAGGTTTACTTAAGCTTCTTATCATTTCAGCAATGGCAAGCCCAGCTTCCACATCTCCTCCCACAGTATTTAATATTATAAAAACTCCTTCTACCTCTTTGGAAGTTTCTAAAGCTATTAGTTGAGGGATTAAATGTTCGTATCTTGTAGCCTTAGTTTGAGGAGATAGCACCATATGTCCTTCTATCTGCCCTATTATAGGTAGAACTTGAATTCGATCTGCCTGTCTTGGTGGTAAATTTGTAGTTCCAAATTCTTTTAAAGTATCTATCTTTTCATTTCTTTCTTTTTCATCTGCCAT

Protein sequences of DBSCAN-SWA_3

>NC_017297|2528453:2588159|2536502_2536814_-|WP_014519348.1|DBSCAN-SWA
MGAVGACKPVEITFGEVINADELKIKVDQKLMLDRDFFIVPESLTKYEIDLKHTHTYINNSSESNLNTSLDKLLIREGLKQGDKVLLLRVQGGQQYVILDKVV
>NC_017297|2528453:2588159|2549468_2550920_-|WP_012100329.1|portal|DBSCAN-SWA
MFFIDKILSNGSNSVMSLEEIIQEEIKEWNSSQTRQLMLDGERYYKGDTDILKRKRMAIGEDGELEEVKNLANNKLVHQFVRKLADQKVGYLLSKPLSVQTDNETYKNVLDDIFNKSFMRLLKNLGKDAINKGIAWAQIYYNSDGELRFKRLPSEEIIPLWKDSEHTKLDALIRVYEVIVYEGKTKKTVQKVEYWDTKQVLRYINDNGKLITDVEAPEDEGHFSIINKDGTKQSFTWSKVPFIYFKYNDEEQPLIKFVKSLVDDYDRNKSDNSNNLEDLPNSIYVLKDYDGTNLGEFRKNMSLYRAVKVTGDGGVETRNLEINVEAYKTHIEQTRKDIYEFGRGVDTQSDKFGNSPSGIALKFLYNDLDMDCNIIETEFQASLEYLLWFVNQHLINTGQGDFTNENVEFVFNRDTLINETDSINNCQSSVGIISDETIVANHPWATKDELEKIKKQKEERESMYPNFPLEETPEDEEDEENEE
>NC_017297|2528453:2588159|2573020_2574451_-|WP_012100360.1|DBSCAN-SWA
MRDIYNNPLNKRYSSKEMSYLFSEEMKFKTWRKLWVALAESEKELGLNITEEQINELKKYIDDINYEVAEEREKEVRHDVMSHVYAYGVQCPKAKGIIHLGATSCYVGDNTDLIIMKEAMILIKKKIINVINNLKKFALEYKHVPALGFTHFQPAQLTTVGKRATLWMQDLVLDLEQLEFVIDTLRFRGVKGTTGTQASFMELFDGDESKVKALDKKVAEKMGFPKEFMVTGQTYPRKVDSTILNTLSEIAQSAYKFSNDLRLLQSMKEMEEPFEKNQIGSSAMAYKRNPMRSERMGALARYVIVDALNPAITSSTQWFERTLDDSANKRISIAEAFLALDGVLKLYMNISENMVVYEKVIESHVKTELPFMATENIMMEAVKKGGDRQELHEVIRTHSMEAARRVKQEGLSNDLIERIIEDESFELTKEEILALIDPKKFTGRAEGQVVDFIEEVVNPILEQNKAMLGEKAEINV
>NC_017297|2528453:2588159|2545955_2546921_-|WP_012100323.1|DBSCAN-SWA
MGTKLSDVIVPELFNPYVVNRTMEKSALVQSGIITNNSEFDGLASQASPLINMPFFEDLTGESEQIIEDTDLEAAKITSNKDVAAILRRAKMWSATDLSAALAGKDPMAAIGELVSGFWTRDMQKELIAILKGVFLSTSMKNNLLDISAMTEGAAKWSASAFIDAQQMLGDAQELLTGVMMHSAVKSELKKQNLIETIRPSDSPEFDVYQDKRVIVDDGCPIDAGGVYTTYLFGQGALALGNGNPVGFVPTETDRDKKKGSGVDYLINRKTMILHPRGIKFTNAKVAKTEGPSRAELQEKTNWERVYEPKQIRIVAFKHKI
>NC_017297|2528453:2588159|2576996_2578280_-|WP_004440270.1|DBSCAN-SWA
MEFNYLSGYENKDSNYSKTNYYKIIIGLSMLLCILWVIFVDTKPFSDFEYYYNLAVSIANGGEWGDTYTSVGYSIVLGGLFKLFGASLALGKIFNLVLTFFGQVLFLGILRKIKITERNRKIVFTLFVLFPNNIFFNSVLGTEILFTTLLLLLTYLYFSDIKYKYVILGVLVGATTMVKPFFLLYAFAIFLVELLKEKSFLKSLKSAIIIAVVALITISPWIYRNTKYNGERTFVSNNGGIVLYINNNSQNNMGRWMSIYDVENSLAETEEYKKASYTQKNKMLNKAAKEWIKSHPKEFVILGFKRLFNTYMVGDDVAYSIHGVTMNDTVKFKLFAATNCIRNMVFIPAIIYVLIYSIFILIQIIKRRTENLNKFNLYSTILFHMFTSVYFITEGQGRYAFPLIFIIIYFWVYFIKHGILLFKELKR
>NC_017297|2528453:2588159|2544721_2545213_-|WP_012100320.1|DBSCAN-SWA
MARLASFDYSDFKNMTKSFQKALDERVIERWIREFLLEMAFRAERKIKKRTPVGVYSNQVSFTTKDGKEVNFTTSSSKTGGHLRRNWQVGNVIKQGDSYVVEIFNNTEYASYVEYGHRTKNHKGWVEGRFMATISMQEIERQLPKFLERKQVELLNQILNGRA
>NC_017297|2528453:2588159|2583277_2584615_-|WP_012100364.1|DBSCAN-SWA
MEKIKVALVSLGCDKNRIDSELMLYKLNEEAELVKNPKEAQVIIVNTCGFIETAKEESINTILQMASYKKTHNCKVLVVTGCLTQRYKGELKELIPEMDIMLGVNDYDKLLESIKVFLKSGEKSFYHKYSDTKINEGNRILTTPTYTAYVRIAEGCNNFCTYCAIPRIRGKYRSRKKENILKEVENLAKQGVKEIILIAQDTTMYGIDIYGKKVLHELLRDISKVEGVKWIRLLYCYPEEITKELIEEIKNNDKVCKYLDLPIQQISNSVLKRMGRKTTKETIIDIIKKLRKEIEGITLRTSLIVGFPGETEGEFSELKEFVSDVKLDKLGVFKYSKEEGTSAALMEEQIDEEIKEKREEEIMILQQSISKDINKEKIGKIYEVIVEGTKEDMYYGRNYEMSPEIDGEIYFEKDENVKIGDIIKVKVTHSLEYDLIGVVYNELSK
>NC_017297|2528453:2588159|2575305_2576499_-|WP_012100361.1|DBSCAN-SWA
MKLSKKAIEIQPSLTLEITAKAKKMKAEGIDVIGFGAGEPDFNTPENIQKAAMLAIEEGYTKYTAASGILELKQSIVDKFKKDNGLNYETSEIIVSNGAKQCLSNLFEAILNEGDEILIAKPYWVSYPELIKLYGGVPIFVDTKEENHFKYEIEELENKVTDKTKAIIINSPNNPTGTVYSKEDLEALAIFAKKHDLLIIADEIYEMLMYGEENHISIASLSEDAFKRTVVINGMSKSYSMTGWRIGYAAGPLDIIKVMSNIQSHTTSNPNSIAQYASLEALKGDKTQVKNMIVEFKKRRDYMVNKVNSIGNLSSINPKGAFYVMVNISKAMGKTIKGNTIKDSISFSKILLEEEKVAVVPGIAFGDDNFIRLSYATSMENIERGLDRIEKFMKKLD
>NC_017297|2528453:2588159|2545597_2545942_-|WP_012100322.1|DBSCAN-SWA
MTPLEKLKKLLGISLDNDSKDFSLQFAIEDAEQTIRDYCHIKEIPEQLNNTILRMAIDIYRNENLGEEENPLGSISSISEGDTSISYRSANAEFKDSLVKDYKAKLHKYRKLVW
>NC_017297|2528453:2588159|2532850_2533192_-|WP_012100303.1|DBSCAN-SWA
MQFGKRLIFDKNTGVILNNSFGEIITTSNIDLRPKEIDFIDLPYSYNENNFKNAIEYHIDIFKNKNTSNLKDLIVITQYMERVETNEEKLKREKQELENQLLLKENKETGGIL
>NC_017297|2528453:2588159|2550932_2552342_-|WP_012100330.1|terminase|DBSCAN-SWA
MDKELIQLGAKIELARRKFFFYCNLKAPDFYKQNRTYLIELCNEFQEFLSSDEEVMIVNEPPRHGKSRTAGLFVEWVLGNNQNEKIMTGSYNETLSTMFSKNVRNSIQEEKADKYKPVFSDVFPGVRIKHGDGAMNLWSLEGGYNNYLATSPTGTATGFGASLLIIDDLIKNAEEAYNEAVLEKHWDWFTNTMLSRLEEGGKIIIIMTRWASGDLAGRALDYYREQGIKVKHISMKALVNKEKKEMLCPEVLSYRSYINKVKAMGEDIASANYQQEPIDLKGRLYSDFKKYKYIPKDNNGNPLFTRIKAYIDTADEGSDYLCCIVYGEYNKEAYVLDVLYTKEPMEVTETATAKMLYENEVNIADIESNNGGRGFARSAERILKEKFNSNKTKVKWFHQSKNKKARILSNATWVMDHIYYPINWRDKWPEYYKAMNKYQREGKNKHDDAPDATTGVAENVGKGNSISFD
>NC_017297|2528453:2588159|2574937_2575195_-|WP_003362134.1|DBSCAN-SWA
MLERELTVNSSTGLHARPATLLVKKASSFKSDLSIEFNGKKANIKSLIGVLSLGVTSGAKIKLIASGDDETLAIEEISKLINTLE
>NC_017297|2528453:2588159|2538517_2540677_-|WP_012100312.1|DBSCAN-SWA
MATVSTALKMFDQMTRPLQQVTQALNLTISAMDNLNNSANRDIRITNTLNTARGAIQRASAGLQELVNQQDRAQNNQNRLNESFNRGSSEANGLTSKVKNLLGAYLGFQAVKKGMDLTVGGGARLEQQLITISGMLGNKDIGKAFFENLNKYANESVYGLKEFNTITRSFIQFTKNTDKLMDLNKTAEKLAFLDPTQGLEGAGFALKEALGGDFMSLKSRFGFGKADAEILKASKSMDEFISKFDELLAKKGATDKALEEFNQSAIAQLNNLKSNIETAFAQASETALEVLKPLLSRINEGFKNGSFEGFFNGISVGLDIIVNLIMDAIDIVTWLGQAVSDNWSIISPIVWGIVAAMIAYNATMGIAWLTTIMDIGAKIGHTIASWAETAAVIALTIAQEGLNAALALCPITWIIIAIIILIALFYAAVAGVNHLAGTSISATGVIAGSFMVALAFIGNLFVAFYNLVVDIIALFYNHFAAFAEFFANVFNDPIGSIIRLFAAMADEVLGILKSIASAIDTIFGSNLANAVGNWQNGLQGAVDKLVGKPKIQFQKMDSSAMHLDRFEYGKAYDSGYGVGKNIGDKFDLGNIFNKGNIPDMGKMPDMAAWNKAQGPGTLGTAGDDGKNKGSKSPSGNKGLKDANNHLKNIDDKIDISNEHLEMMRDLAEMESIQNFVTLTPTVQVTTGDIKEEADINKIISKIENYMENELANSAEGVYA
>NC_017297|2528453:2588159|2569761_2570139_+|WP_012100357.1|DBSCAN-SWA
MISILGQNIKKIRTEKGLSAYKLSKLARVGTTTISEIENGKRQSLNSTTIEKIANALNISTDRLMDVEENKEYIVTDIEQTIKLILTSDELVLDDIKLSDTEKLQIESVLNATFAMIRSQRSRNS
>NC_017297|2528453:2588159|2584709_2586986_-|WP_003388321.1|DBSCAN-SWA
MAKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSLVFPILIIFTGCCFIGKKNKINLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKFYREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIISFILIFQVSLGTILQTLQVKRSIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLNIVDNSVSENIEKSKEDTGEEAIKEELSKNINEGGNNVKIEYNYPTLELLKQNIQSKLNKQDKKELINNANKLEETLSSFGVEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALNLAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDEFQKFDDGLAFALGKDISGSCVVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIPHLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVIIIDELADLMMVCPNDIEDYISRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISFAVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQGAFISESEVEKVVSCIKDEQGEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARIIEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM
>NC_017297|2528453:2588159|2554068_2555433_-|WP_012100334.1|DBSCAN-SWA
MDFKPWSYQEYAIKHIINNPAAGLFLDMGMGKTISTLTAIDNLLFLGDINKILVIAPLRVAEDTWSTEVDKWDHISHLRVSKILGTKKQRREALMKDADIYVTNRENIDWLVNECFSSWLWDMVVIDELSSFKSSKAKRFRALKKVRPYFKRIVGLTGTPAPNSLIDLWPQIYLLDGGKRLGKTITSYRQQYFNPGRRNQYVVYNWELKEGAEEQIHKKIGDICISMMAKDYLDIPARIDNVININLPKQSMDKYKQLEKDLVIELGEDDITATNAAVLTNKLLQMSNGAIYSEDKSVLEIHEEKLKALLDIIEAANGKPVLIFYSFKHDFDRIVNFLKTKKLNAIGLEDSKDIKKWNNGEIPILLVHPASAGHGLNLQYGGNIIVWFGLTWSLELYQQANARLHRQGQKESVIIHHLVSKDTVDEDVIKALDSKEVNQNVLLEAVKARLKESR
>NC_017297|2528453:2588159|2542163_2542628_-|WP_012100315.1|tail|DBSCAN-SWA
MSFLEFKDTISGQEGRAYATIDGRNEELFYAKKIESKVEKEKSEGKTLGKRGTQSKAKGYKGTGTLTIYYITSLFREMMIKYMKEGIDTYFDMTVVNEDPTSTVGKQTTVLKNCNLDECPMALLDVDSDSLEEEIGFTFDDVDLLDKFSKPVLG
>NC_017297|2528453:2588159|2566641_2566896_-|WP_012100350.1|DBSCAN-SWA
MDKNYEIIQDILFRAIQITVTQKHDVSWEFYPLTRTLRISIPFNNGSLIKTYGVKVEDTECLKIIQKELMGIQTNNLEDDFLGD
>NC_017297|2528453:2588159|2556137_2558561_-|WP_012100338.1|DBSCAN-SWA
MEAYKTEDKPKIKYDGSIAIATGKSRKETHWKNKNILWSELVGKLSNTTRTPETYAEYKKMAKTEKDMIKDVGGFVGGGLKNGRRKAENVQNRTLLTLDLDYVKGDIWSSIELLWDFSVAMYSTHTHAADNQRLRLVIPISRPVLPDEYQAISRMIASDLGIDQFDDTTYEPSRLMYWPSTSSDGDYIFKIQDEPWLNPDEILARYTFGWQDVSYWPESSRARAKLNNAIKKQEDPLEKKGIIGAFCRTYTITEAIAEFLNDIYVPGADETRYTYAEGSTTGGVVVYENKFSYSHHGTDPASNTLCNSFDLVRIHKFGHLDDEAKPDTPANRMPSFTRMSEFASSDEKVMQTLGKERMEKAQEDFGIVETEEVDTEWLKKITYTEQGKVRSTISNFLLIIENDPMLKGKIAYNEFSNRAVVIGQLPWRKKDNGSDWNDTDDSGLREFIEKYYSISSTAKCADALALVFEKYSFHPIKEYLNSLKWDGKERINTLLIDYLGAEDSNYVKTVTRKTLVGAVARIFIPGIKFDTMLVLSGPQGIGKSTIIKKLGKDWYSDSLTTVSGKEAYEQLQGFWLIEMGEMTATKKADIEATKHFLSKQEDIYRVAYGRRTSRFPRQCIFIGTTNDKEFLRDKTGSRRFWPVDVGTQKHNKYVWSDLTDYEINQIWAEAVELWKNKEPLNLNNEEKKEAEKQQDAHSEESAKTGLIEEYLNKLLPDDWYSLGLSERRNYIQGTDFGEIPEGNLRRDKTCVMEIWVELFNGDPKQLTPLHSREINDILKGLKGWERHKSKLRFGKVYGIQRAYIRKI
>NC_017297|2528453:2588159|2529810_2530002_-|WP_012100297.1|DBSCAN-SWA
MGKSKQTIANQNWEKKNREYASYLKSRSSARSFIRNKATLEDIEEFMDLLKEREELLKQELGD
>NC_017297|2528453:2588159|2528453_2528696_+|WP_012100293.1|DBSCAN-SWA
MVFKDRLKGLREDRDLTQDQIADVLSITRSAVANYENGIREPDMALLVKISDYFNVSLDYLLCRTNKMEPFYKNNKKNKL
>NC_017297|2528453:2588159|2582709_2583294_-|WP_003362543.1|DBSCAN-SWA
MNLANKLTILRIFLVPIFLIFISVKNIPYGTVIATAVFVIASATDKLDGYIARSRNQVTRFGKIMDPLADKMLVTAALISLVDFQIVPGWACIIIIAREFAVTGLRSVASAEGVVIAASKWGKAKTVIQIVAIIFALVNLNYKEGIYILGNWAVNYINIIANITNITMALAIIITIVSGVDYFVKNKDVMSHDK
>NC_017297|2528453:2588159|2566149_2566596_-|WP_012100349.1|DBSCAN-SWA
MKITAEFNSNEELLNFISTFGANTIQKIEPKQVGQASTEKKEVIKETSKKEVKKDINKEESKSVEPSKQDTKKEKNPPAEQTKKEDKPVEEPKTEITKEMVRAVFTKLIQAGKQKEAKEITAKYGASKLPELKEEHYAAVIKEVEALL
>NC_017297|2528453:2588159|2571707_2572970_+|WP_041173165.1|DBSCAN-SWA
MNFRCTGCAAAISAKKAGADVSIFEKTDLLLGLGNVGGIMRNNGRFTAAEELIALGAGDLINITDENSRHKNIDFPGHKHAWLYDVNKIEPAVKNHMKNMGIDIHLISRIVDVKKEGDKIKGIYISDGTYVDGDVFIETTGSTGPMGNCLRYGNGCSMCVLRCPAFGPRVSLTSRAGVDDFQGEREDDLLGAFSGSCKLAKETMSDELVKELDETGVLVLKVPKEDINLDKLKMKVCQQYALKEFAENIIILDTGHAKLMTSYYPLDKLRKLKGLEKVKYIDPYAGGKGNSIRYLSVAPRTDDMKVKGLENLFVGGEKSGLFVGHTEAITTGSLAGHNAVRYCLGMPMLILPRSMALGDLIAYANHKLYSKEGRKNRYTFAGAEYFKRMVEENLYTTDKEGINKRISKLNLENALAQRLV
>NC_017297|2528453:2588159|2563745_2563925_-|WP_012100344.1|DBSCAN-SWA
MNSRELMPIMKKYEKCPKCGNNKIGNGEGGIIVEDDTYTRTCKCGFKITVDENSKKVNL
>NC_017297|2528453:2588159|2529113_2529515_-|WP_012100295.1|DBSCAN-SWA
MLYGYCRSGNLNSKSLENQIEWVKSNGVEEENIYKDTGSANDTNRVELNKLFDIVQEGDTIFCKDINRLTRSHKGLEKIIEFAKTKRVKFVLANSIIDGLKIIDGIEGVDIGVEAISAMISTLKEYEESIENK
>NC_017297|2528453:2588159|2553682_2554060_-|WP_012100333.1|DBSCAN-SWA
MKLLMQVLRKNDKLKIDNTTITSKELITKITEEYKEVIEAIQKYENNKRLINLKDIIRETYDLIQMCILVLWKCHRKALTLDEPNLIKELNEEHRVKLIDERKWTSKANIDIELKEQEGLYCGTK
>NC_017297|2528453:2588159|2537840_2538518_-|WP_012100311.1|DBSCAN-SWA
MYKMYLGINEGEEGFVLPVLPEKIEFDEDGNNKTYDVINLGEINTINLPKLTEISFESFFPKHKGPYVSSEQLFEPSFYIAKIREWRNKKQKIRFIFVGSPLEVNDLFTIESFKPSEEGGEVGDIHYSIELKRYKNYAAKKVVIVTPKTAAANQSVKKVIANSKAARPSNTNKPKTHTVSGNDTLWHIAKRYLGDGNKWPQIYNLNKDKIKNPNLIYTGQVLRLP
>NC_017297|2528453:2588159|2559998_2560229_-|WP_012100341.1|DBSCAN-SWA
MYYKFTDTEIKKLLKEKFMILYDTREQKNQHILNYFDEKKVKYKRKKIDEGDYTAIITKLCKLNLVCSLVINIRSN
>NC_017297|2528453:2588159|2553144_2553696_-|WP_012100332.1|DBSCAN-SWA
MEQNNITYEEAVKIGIREGIKYIKEQEYHKTTKRYDRRLRNTRLLLKHYRTLNIHNKIANNAVRQVNEENAIDILDEIDSINDEEQYVQAICRTKIRTLIIIEHMNKAISYYQSICKNEGKNKERRYNIIKYIYMDSPGNSNTPTYEEVAEHFNINVKTVSRDIKSSIEDLSVLFFGIDGIRL
>NC_017297|2528453:2588159|2532666_2532849_-|WP_012100302.1|DBSCAN-SWA
MVNEIVVRIIAERIIYKGENPLRQRPFLLDDVTNEEYRKAVEDYIIKNTADVTGVEEATQ
>NC_017297|2528453:2588159|2531474_2531729_-|WP_012100300.1|DBSCAN-SWA
MELKVCEEKHKRIEEKINVHDIRINNHSERIDKIEVTLAESKADIKNLCKDIRNLTSILKWLCTLMGSSLVAFFFYAIQHNLFK
>NC_017297|2528453:2588159|2548245_2548440_-|WP_012100327.1|DBSCAN-SWA
MNDVSTHGVQRIKAAIFKFSGDFRIADIVTEALIGNGYDIDIEPINDEFHRPQGEKINVYTVKR
>NC_017297|2528453:2588159|2564840_2565986_-|WP_012100347.1|DBSCAN-SWA
MTKHAILSASGASRWLACPPSARLEQDFPNKSSEFAKEGTLAHELGELGLKKNLELISTRKYNSEFKKIEVDKLFTKDMPDYVEVYVDTCMEKVAEAKAKTPDALFKIEQRLDFSEWVPDGFGTGDFVIIADGTMEICDLKYGKGVPVSAVNNKQMRLYALGAIAEFSFLYDIENIKMTIIQPRLDSISTDEMKVEELLKWAEEELKPIAKLAYEGKGEFCAGDHCKFCRAKAVCKARADKNMELAKYDFQEPITLDNNDVAFILGKADELINWAKDVQEYALEQALQGEEFDGFKVVEGRSNRKWTDEEKIGKILLGQGFLEDIIYTKKLTGITNMEKAIGKKEVTKLLGDYIIKPQGKPTLATITDKRPVYNSAEADFK
>NC_017297|2528453:2588159|2574688_2574910_+|WP_003395736.1|DBSCAN-SWA
MYKVSLIDKISFILVTVGAINWGLIGLCNFNLIGVLFGEPANFVGRLIYILIGAAGINMVLFLIKTKGSLKHK
>NC_017297|2528453:2588159|2563955_2564126_-|WP_012100345.1|DBSCAN-SWA
MKKLFIKCNDKSKATYTMKDFVDHMEYVNKYINKSYVESIILQQYPKKDNKPIIYK
>NC_017297|2528453:2588159|2555595_2555877_-|WP_012100336.1|DBSCAN-SWA
MEESRIEKRLKKEIEKLGGKALKFVSPGVSGVPDRIVLLPEGRIIFVELKAPGKKPRPIQKYRIKELRSLGFRVEIIDSIERINNFVEGIKNE
>NC_017297|2528453:2588159|2560277_2561708_-|WP_012100342.1|DBSCAN-SWA
MKELIIDNFAGGGGASTGIELATGRSVDIAINHDPAAILMHKTNHPATKHYCESVWEVDPVEAVGNNKVALAWFSPDCKHFSKAKGSKPVDKNIRGLAWVAVKWAKLVKPRVIMLENVEEFKTWGPLKEDGKGNLYPDPNKKGQTFELFKKALEKQGYKVEFRELRACDYGAPTTRKRFFMIARCDGKPIVWPESTHGDPEQIEVRCGLLKPWRTAGEIIDWSIPCPSIFTRKKPLAENTLRRIAKGFQKFVIDNANPFIVRIGQTGFAKDGLQYELDSPLTTITTKAEHLLIAPFLTSYHSETQQGEVRGLSLDNPIHTLDTSNRFGLVAAFITRQFKSSIGHKIDEPLATVTTVDKSNLVTAFLLKYYGTDIGQKINEPLHTITTKDRFGLVTIKGEDYRIIDIGMRMLQPHELFKAQGFPEDYIIDHDYEGSVYPKTKQVARCGNAVPPPFAKALVEANLPELCKDRKSEKVS
>NC_017297|2528453:2588159|2529559_2529805_-|WP_012100296.1|DBSCAN-SWA
MKKVVISLLTGLLIGASTRFVGVANAVAPAEDNGRENGYYMYCLDKAKPVWVSLNKVKEGEKFLYLSNPKNNIVIKLVKIN
>NC_017297|2528453:2588159|2547566_2547830_-|WP_012100325.1|DBSCAN-SWA
MAKYKKKPVIVEAVQYTGDVNTTEIEDMSFYEAYRDGVIREEKGNLLIKTLEGTMIANKGDYIIKGVNGEFYPCKPDIFKKTYELVE
>NC_017297|2528453:2588159|2547846_2548215_-|WP_012100326.1|DBSCAN-SWA
MYKLNTIQKREKLNEVYVLDDKGPGGANHVYMICKKDKDILDSVLVDINFQKGPRKEGSSTNGILDTDLLEIVRNRLQGFQEGPYACEYNEKALKHIEEALMWLNRRVEDRIDRNVLGTNNK
>NC_017297|2528453:2588159|2578298_2579165_-|WP_004440805.1|DBSCAN-SWA
MDIKGIIALMRPKQWIKNFFVFAAIIFSGNLTNEIILKNNIITFILFCLTSSTIYILNDIVDLEKDKKHPEKKNRPLPSGRVSKSTAIIMNIVILFTVLFCSYKFVDYKIMYIYLLYIVMNIFYCFKLKNVVILDVMVITFGFVLRMESGSLATKVSVSPWLFLCTILLSLFLALNKRKSEIITLKDNRGSHRKILEEYSVELIDNMLTIVTPSILISYCIYTFSSVQSKRMMYTIPFVLYGIFRYQYLMNNHNLGGKPEDVFGKDKPFLVNMVLWVISVVVIIYFKL
>NC_017297|2528453:2588159|2576643_2577000_-|WP_004440581.1|DBSCAN-SWA
MIYLILTSVFLGALGQILVKYGAVNLTLNFSPAHFLPSIVSILKNMPVMAGIISYGVSFLLWIKVLSKVELSYAYPMVSLGYVLVMIFSYFFFKENITPIRILGVAFIMIGVILVARS
>NC_017297|2528453:2588159|2536092_2536500_-|WP_012100307.1|DBSCAN-SWA
MSEVSILPRGAILDEDIEVEQIIEPTKTYKIKDNRIVGFIDNVEALKQAIALILNTERYEYLIYSWNYGSELNGLIGRQKDIAESEFKRRIREALSQDDRINNVDNFIFNYDKDGVEVSFTVFSIYGEFAESVVK
>NC_017297|2528453:2588159|2542631_2543942_-|WP_012100316.1|DBSCAN-SWA
MAGGTWERQNKIRPGAYINFKSKKNGQTPIGERGIATLPLELPWGPEKQVLPIYADDDLSKVLGINIADESALLIREVLKKAKILLLYRLNEGTKATATLEGLTINAKCTGTKGNNITVIIQNSIDFTESFEVITIFEGNKVDKQLVKTIEDLKDNDYVDFKGTGDLKTSAGLPLKGGADGNVTNQGYTDYLATIEPYEFHAMGIPTKDPTIKAVATTFIKRLKEDGRQVQLILENYPEADSENVISVKNGVILSDETIIKSDKAVAFLTGATAGANVNQSNTYLEYPGAIDVDTKYTNREIEEALLNGEIVFTISNRKVVIEQDINTFKSFTEDKGKDYRKNRVVRTLFEVNNGSRLLWETNYIGKGDNSEDGRNLYKKDVIKFLEKLQGIGGLENVVPEDVEIKRGQDKDSVVARMGVQPIDAMEKLYMDVEVE
>NC_017297|2528453:2588159|2579727_2581269_-|WP_012100362.1|DBSCAN-SWA
MGPTKYIIIAVVIIIICVILGLYVVDKKAKEKLSEASKEARRLKEEAERDAEAKKKEAILEAKEEAHKLRAEVERENRERRNEVQRLERRIIQKEEALDKKSEALENKEEALNKKQQKIEDVEAHMEELHEKQRTELERISGLTTEQAKEFLLEQVRKEVKHETAVMIKEIETKAKEEADKRAREVITYAIQRCAADHVAETTVHVVNLPNDEMKGRIIGREGRNIRTLETLTGVDLIIDDTPEAVILSGFDPIRREVARIALEKLIVDGRIHPARIEEMVEKAKKEVEVSIKEEGEQATFETGIHGLHIELIRLLGRLKYRTSYGQNVLKHSIEVSHLAGLMASELGIDPTLAKRVGLLHDIGKAVDHEVEGPHAIIGSEIAKKYRESALVVNAIGAHHGDMEPQSLEAILVQAADAISAARPGARRETLEAYIKRLEKLEEIANECEGVEKSYAIQAGREIRIMVKPEVLDDTGCIEMARNIVKQIESELEYPGQIKVNVIRETRAIEYAK
>NC_017297|2528453:2588159|2556031_2556184_-|WP_154018630.1|DBSCAN-SWA
MVKSMVFKELIYVKFSVTKVKLKDVTNVTIKNHFGNAFGNTLKLDISMLI
>NC_017297|2528453:2588159|2567210_2567762_-|WP_012100352.1|DBSCAN-SWA
MINAEEHLGIVYLITNKRYKQFKHKYSYEDLFQEGCLGLMKAANRFDSSRRIKFSTYAYPYVDGQILRMIESDKWYGKNRKERLEGIVPYSLDAAIDGLDNEIAYIDSIGNYDLNFEKIEIKTLIDSLPEKLKEIMEMYYMQSFTQAEIARKIGCSRSNVTRLKIEALDYLRFQVNSIKKEMA
>NC_017297|2528453:2588159|2579328_2579589_-|WP_003362540.1|DBSCAN-SWA
MEVLKVSAKSSPNSVAGALAGVLRERGAAEIQAIGAGAINQAIKAVAIARGFVAPSGIDLICIPAFTDIEIDGEERTAIKLIVQPR
>NC_017297|2528453:2588159|2587466_2588159_-|WP_003388341.1|protease|DBSCAN-SWA
MADEKERNEKIDTLKEFGTTNLPPRQADRIQVLPIIGQIEGHMVLSPQTKATRYEHLIPQLIALETSKEVEGVFIILNTVGGDVEAGLAIAEMIRSLSKPTVSLVIGGGHSIGVPLATSADYSFISPTATMIVHPIRMNGLIIGVPQTFEYFNKMQERIIEFIVRTSKISKEKLKEFMLQSDELLNDMGTILIGKQAVESGIINEVGGVKEALDKLNNLIDEKQKEDVSK
>NC_017297|2528453:2588159|2566895_2567147_-|WP_012100351.1|DBSCAN-SWA
MNKKVAMVKFPRGSFDQEYSYKTDIEDLKNGDVLVVEANNSYSIAIFQRYSETKSRVEQATKWVVQKVDIESHEAKMFLGGSD
>NC_017297|2528453:2588159|2581503_2582562_-|WP_012100363.1|DBSCAN-SWA
MANKVNPEKLKAIEAAMGQIEKQFGKGSIMKLGEDSILNVESISTGSLDLDIALGIGGVPRGRIIEIFGPESSGKTTVALHILAEAQKIGGAAAFIDAEHALDPSYARNLGVDIDNLIVSQPDTGEQALEITEALVRSGAVDVIVVDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKLAGSINKSKCVAIFINQLREKVGIMFGNPETTPGGRALKFYSSVRLDVRRIDSIKQGDQILGNRTRVKINKNKVAPPFKMAEFDIMYNEGISKVGNILDVGVREELVDKSGSWFSYKDTRLGQGRENAKQFLKDNMNIALEIENTIRKKHDLPVADAKNLNIENKKQDNKEG
>NC_017297|2528453:2588159|2541732_2542146_-|WP_012100314.1|DBSCAN-SWA
MNNFEDFLMDSFEEVEEIEREITIGGKKKKMKFKPISADKGDELRKKCKKVKLVKGQKMIETDQDKFVSNQIIETTIYPDLKNSELQKAWGVIGAEELLSAMKSRMTDGEYADWSSTVIEINGYDKGMQELVEEAKN
>NC_017297|2528453:2588159|2559675_2559960_-|WP_012100340.1|DBSCAN-SWA
MKEILNANLEVKVFKYESEKELNKHKDKMLKDGWKCTRSGQYNLSPVSTITAFCNEKNWYYVAEFNKKNEFININKPTSYESEAYWFTIYEPED
>NC_017297|2528453:2588159|2540734_2541496_-|WP_012100313.1|DBSCAN-SWA
MGLFFKSKEKCCICGNEEGKKKISSGFICKQCLHLCSINFQVKINKNTTKEAILIEMEKNKNNKKLVADFTTTKKIGPYIEFDEQKGLWLIPDGFGGKKVNPRIHAFGDIVEYELLQDGDSITKGGLGRAVAGGVLLGGVGAVVGGVTGKKKTKSVINNLRIKITVNDTSNPSVYIDLIKTPTKDNSFIYKTAYSSAQEILSMLSIITQKTSDKNINTKTSVADELIKLKGLLDEGILTQEEFTSEKNKLLNK
>NC_017297|2528453:2588159|2558607_2559633_-|WP_012100339.1|DBSCAN-SWA
MDKIRDILINEAVLHVLDNNSDEPILNNYKIALTDEVYKFILSHTERILKDNDLKYATFKESSTAIRETSQEYLNGQSDLLGASNCIANNLFSFMKSDINIPSCNLFVVSISTEYGPMLGILKLDYIKQYAHEIDFIDDNVVIRITPTTTGLPATKKVQKAAFIRPICNDQEYNLLVLDKVKSKKSDEYGTDYFTEKFLECLLIDNDRDNTRVFMNAVENWTRSNLKEDAVKAEEIRSFAKSELRENEEIDIYNFASKILPFEESKKDFIAYMQANDIEKVKVDKEYLEKRLSRLKLKIDSNIEISITEEAYKDINRFGIQNNGDGSITFMIKNVDRYVEK
>NC_017297|2528453:2588159|2545212_2545596_-|WP_012100321.1|DBSCAN-SWA
MLKGIEKARKQARKAIESLYDCTCNITGGKEKVKDPVTKETKLIPKIKYEKQSCKISKQSLSKNNQTDTVNKVLYEIKLFIAPEVEIKQGDEIEITNQFGIITKYKAGEGFPYYTHQEVILNKEDKA
>NC_017297|2528453:2588159|2531749_2532505_-|WP_012100301.1|DBSCAN-SWA
MSKLDKYIELIFVGIITALLYYFTYMFQVGYLSYYNIPSAFVEINSSIVIRRIIFLFTITTLVLLSTQGIFSVLVDIFPKWISNDIKILSVCLSGILWLSSVSVKYHKIPSMLILLIILFILKICQIRVKYKQRSIEKEIANKNTPMFFDGIIKNHPKIYNILICMIIIMFIGDLVKNIGGLIVELNPREIEININNRRAILVSEYRSKLIIKYKKANSNELEDGFNIIEIKDDFKMIFNKEKGVFNIAPF
>NC_017297|2528453:2588159|2546940_2547546_-|WP_012100324.1|DBSCAN-SWA
MPKLSEILEEFYSQIPEELQAKYKDVDLVDSKQYITKDKFDALDEQLKNADTTITDLKKSNKDNEELQIKVTDYETKVKDYEKKIQDMQFNYALEGALKGANVRNTKAVKALLNLEGVKLDGENILGLKEQIEALQKSDSYLFAEEQKPKFSGVEPTDGSKTSQGYNPWKKESFNLTDQGKIFKENPEQAKQLMAQVGINQ
>NC_017297|2528453:2588159|2530430_2531198_-|WP_012100298.1|DBSCAN-SWA
MLFNLNPGHTLSGGDVGTRGINGLKEEVLTRQLVGEIDKELRGRGHSTNICRVDYASTLQESLNKQVALCNSVNADLNICIHFNTTVGGYGSEVYTYNGKYLVEADRALKQLNNLGFRNRGIKDQPLALTKRTKAKTIYIEVCFIDSSHDVAILNKYGMNGIAKSIVNGVLGTSSNVTPSKPSTSDNGWVNLDCKTGTINTPSGVNIREAKNTSSKILGALPNGAKVQLYRKEGDWIHIYYPPHGGYVYGKYIRY
>NC_017297|2528453:2588159|2533203_2534385_-|WP_012100304.1|tail|DBSCAN-SWA
MAEQFYTILTKIGKAKIANATALGNKVNFTTLKVGDGKGKYYNPTEEQEGLVNEVWQVNINSIRVDENNPNWVVIEVIIPSSVGGFMIREAGVFDDENNMLAIGKYPETYKPQAQDGSTKDLVIRTNLEISNTSSVTLKVDPTVILATQKDIQIINSNMVDLGERVSKNEENITSIKSDLADITTDNKRLTKDKTITGAINELFTNANNGKSLISSVVGTPLLATDTFQQQRDKIQTLKNTFATNLTAKQQVSNGSESLLNLINKVANINTGKKYAKGELKEVEFTENFIISYLDFKPSIILISGWENRSPNYVDFTINMIYTSDGFICGGQYTSDQLKGSTLSVRAGAGSGNNFKFTTDFTDDITATNNGFAIQKNFFLTCIHSNFKWIAIE
>NC_017297|2528453:2588159|2531242_2531437_-|WP_041173229.1|DBSCAN-SWA
MKFLEQFLQIKKIIALLTTIVFCILSTKGNLSSTEFLSVFTLIIGFYFGQSSARQAVKESKEQD
>NC_017297|2528453:2588159|2548456_2549488_-|WP_012100328.1|DBSCAN-SWA
MKRMRSKDYWKKRSEVVASKQFKKTDNYILSLHLEYIEALSSIQKDIEVFYARFSQNNEISLQEARRLLNSNELHEFKMDLKEFTRKAKDNKNLQWEKELNNVSYKVRVTRLQALQTQIRNQIENLYTKQRNDTSNILSGIYEDTYYRNIFEVHKGLGIGINFAKLDTNIINKVITEPWHGDNYSSRIWNNKEKLIMELQTNLTQSFIRGDSIDKTSKVIAERMEVGKSRARTLVNTESANIVSKSTFNSYIGSGVVKEYEILATLDLHTSKICRSLDGKVFKVSEKEIGVNAPPFHPNCRTTIIPYFPDTIDIERITRDYEGEIYYVDGKTNYKQWYEKYIA
>NC_017297|2528453:2588159|2536850_2537825_-|WP_012100309.1|DBSCAN-SWA
MNIQLLLDNKKGEIFDISELTSEVTWKTKRKDKPSSLDFEILKDKQITITNGDVISFKVDNNPVFYGYAFENGGSKNPITKVTAYDQLRYLLFNDTYVFKNKKASQILIQIAKDIGLRVGTIEDTGYVIPQLLEDDKKLLDIIYSSLEKTLMNNKRTYTLYDDFGYLNLKNINNMKQPVVISDDSNLGDYDWKNSIDSDTYNRVKIVRDNKDTKGRDVYIAQDSRNIARWGRLQYFKKVDEKMNKAQIQEMVNAALKLKNRETKTLKLKDVISTDIAADLKLRAGSGVYVDIKEKGIKQYYLIEEATHKFSKGQLVMDFDLKVV
>NC_017297|2528453:2588159|2569272_2569470_-|WP_014519351.1|DBSCAN-SWA
MNKLKKILDTKKMSVYKLAKKADVGQATAHELVHGTREPRVSTARKIASVLNCSIEEIFFRGGGK
>NC_017297|2528453:2588159|2544103_2544577_-|WP_079992187.1|DBSCAN-SWA
MYNNNSSVVKVGDNISNINDLRIGINQTLDKEFPNINIYGEEIKQDFEEPCFFIKVLSSGQGKELNIRYKKNISFDIHYFSDKEDLNNDYNDMVEKLYEVLEYVKVNNSLYRSSKMTHEVIDGVLHFMLQFNYHVLKEIEKAPKMNKLKQEVYLNGR
>NC_017297|2528453:2588159|2552334_2552922_-|WP_012100331.1|terminase|DBSCAN-SWA
MAKLTHKQKKFCDEYLIDLNVTQAAVRSGYSKKYAMAHAYELLDKPKIKEYIDKKIKDREKRTEITQDFVLKELYAIAKSNGSNYAKVVQKSYIKPVYDKEGNKIDEEEVFYKDVELTLTDDLPEDKKKAIAAIKQTKFGIAVESCDKVKALELLGKHLGMFKDKVELSGDMNVNNPFQDLTTEQLLKLAGEEDG
>NC_017297|2528453:2588159|2568121_2568973_-|WP_012100354.1|DBSCAN-SWA
MKKINLTIENGQPVATEIKAVEINGQRVLTTEQLAEVYGVEPIRIQQGFIRNKEKFQKGKHYFRLIGEELKEFKANYLKDSSLKYASELMLWTERGANRHCKILDTDKAWEQFDNLEETYFRVKENKVEVNQLSPELQMFNNLFKALATTELEQKKLNVAVQETKEEVQAIRDVVKLDTTSWKEDSTKLINKIAQNFGGFEYIREVRKEIYTLLDKRMGVNLEQRLTNKRRRMADEGVCKSKRDRLNKVSVIGDDKKLIEGYVSIVKEMAIKYGVKAQRGCRY

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012100293.1|2528453_2528696_+	helix-turn-helix transcriptional regulator	A0A0A7RUJ5	Clostridium_phage	1.2e-13	50.0
WP_012100295.1|2529113_2529515_-	resolvase	A0A2H4J078	uncultured_Caudovirales_phage	9.3e-24	51.6
WP_012100296.1|2529559_2529805_-	hypothetical protein	NA	NA	NA	NA
WP_012100297.1|2529810_2530002_-	hypothetical protein	A0A0A7RTH9	Clostridium_phage	1.2e-16	82.5
WP_012100298.1|2530430_2531198_-	SH3 domain-containing protein	A0A2H4J8A3	uncultured_Caudovirales_phage	8.7e-87	64.3
WP_041173229.1|2531242_2531437_-	hypothetical protein	NA	NA	NA	NA
WP_012100300.1|2531474_2531729_-	membrane protein	NA	NA	NA	NA
WP_012100301.1|2531749_2532505_-	hypothetical protein	NA	NA	NA	NA
WP_012100302.1|2532666_2532849_-	hypothetical protein	A0A0K2SUB6	Clostridium_phage	2.0e-13	69.1
WP_012100303.1|2532850_2533192_-	hypothetical protein	A0A2H4J342	uncultured_Caudovirales_phage	9.3e-33	64.0
WP_012100304.1|2533203_2534385_-|tail	phage tail protein	A0A2H4J039	uncultured_Caudovirales_phage	8.2e-68	61.0
WP_012100307.1|2536092_2536500_-	DUF2634 domain-containing protein	A0A0A7RTH1	Clostridium_phage	7.0e-51	76.9
WP_014519348.1|2536502_2536814_-	DUF2577 domain-containing protein	A0A0A7RTJ2	Clostridium_phage	1.6e-31	68.9
WP_012100309.1|2536850_2537825_-	hypothetical protein	A0A0A7RTZ4	Clostridium_phage	1.1e-155	84.0
WP_012100311.1|2537840_2538518_-	LysM peptidoglycan-binding domain-containing protein	A0A0A7RVP5	Clostridium_phage	1.7e-94	76.8
WP_012100312.1|2538517_2540677_-	hypothetical protein	A0A0A7S091	Clostridium_phage	7.0e-134	46.8
WP_012100313.1|2540734_2541496_-	SHOCT domain-containing protein	X5JB37	Clostridium_phage	2.2e-42	42.4
WP_012100314.1|2541732_2542146_-	hypothetical protein	A0A0A7RTN3	Clostridium_phage	1.4e-54	76.3
WP_012100315.1|2542163_2542628_-|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	7.6e-62	74.7
WP_012100316.1|2542631_2543942_-	hypothetical protein	A0A0A7S087	Clostridium_phage	1.0e-212	84.6
WP_079992187.1|2544103_2544577_-	hypothetical protein	A0A0A7RTI2	Clostridium_phage	4.7e-51	75.4
WP_012100320.1|2544721_2545213_-	HK97 gp10 family phage protein	A0A0A7RTT0	Clostridium_phage	3.3e-63	76.5
WP_012100321.1|2545212_2545596_-	hypothetical protein	A0A0A7S083	Clostridium_phage	6.3e-54	82.7
WP_012100322.1|2545597_2545942_-	hypothetical protein	A0A0A7RTX9	Clostridium_phage	5.3e-44	77.2
WP_012100323.1|2545955_2546921_-	hypothetical protein	A0A0A7RVZ1	Clostridium_phage	2.4e-142	77.9
WP_012100324.1|2546940_2547546_-	scaffold protein	A0A0A7RW68	Clostridium_phage	4.2e-20	40.8
WP_012100325.1|2547566_2547830_-	hypothetical protein	A0A0K2FMK5	Brevibacillus_phage	8.2e-21	54.8
WP_012100326.1|2547846_2548215_-	hypothetical protein	A0A2H4J4N9	uncultured_Caudovirales_phage	8.2e-35	63.9
WP_012100327.1|2548245_2548440_-	hypothetical protein	NA	NA	NA	NA
WP_012100328.1|2548456_2549488_-	primosomal protein	A0A0A7RVY7	Clostridium_phage	8.2e-149	76.7
WP_012100329.1|2549468_2550920_-|portal	phage portal protein	A0A0A7S074	Clostridium_phage	6.2e-235	87.9
WP_012100330.1|2550932_2552342_-|terminase	phage terminase large subunit	A0A0A7RTS1	Clostridium_phage	1.4e-212	87.4
WP_012100331.1|2552334_2552922_-|terminase	terminase small subunit	A0A0A0RSW5	Bacillus_phage	7.2e-25	40.2
WP_012100332.1|2553144_2553696_-	hypothetical protein	S5MNT8	Brevibacillus_phage	2.1e-13	29.9
WP_012100333.1|2553682_2554060_-	hypothetical protein	NA	NA	NA	NA
WP_012100334.1|2554068_2555433_-	DEAD/DEAH box helicase	A0A1S7FYY5	Listeria_phage	3.3e-161	62.0
WP_012100336.1|2555595_2555877_-	VRR-NUC domain-containing protein	A0A0A7RTE1	Clostridium_phage	1.2e-20	78.3
WP_154018630.1|2556031_2556184_-	hypothetical protein	NA	NA	NA	NA
WP_012100338.1|2556137_2558561_-	virulence-associated protein E	A0A0A7RTG3	Clostridium_phage	0.0e+00	88.2
WP_012100339.1|2558607_2559633_-	nucleoid-associated protein	J9QE81	Clostridium_phage	1.1e-44	32.6
WP_012100340.1|2559675_2559960_-	hypothetical protein	NA	NA	NA	NA
WP_012100341.1|2559998_2560229_-	hypothetical protein	A0A2D1GQA7	Lysinibacillus_phage	1.2e-10	51.5
WP_012100342.1|2560277_2561708_-	DNA methyltransferase	A0A1I9KFD6	Aeromonas_phage	5.9e-113	46.1
WP_012100344.1|2563745_2563925_-	DUF3797 domain-containing protein	A0A0H3UYX0	Geobacillus_virus	1.1e-11	53.8
WP_012100345.1|2563955_2564126_-	hypothetical protein	NA	NA	NA	NA
WP_012100347.1|2564840_2565986_-	DUF2800 domain-containing protein	A0A0A7S066	Clostridium_phage	9.0e-197	88.7
WP_012100349.1|2566149_2566596_-	hypothetical protein	A0A0A7RTD8	Clostridium_phage	2.6e-06	47.5
WP_012100350.1|2566641_2566896_-	hypothetical protein	A0A0A7RTF9	Clostridium_phage	2.4e-25	68.6
WP_012100351.1|2566895_2567147_-	hypothetical protein	A0A0A7RTK9	Clostridium_phage	1.5e-27	70.0
WP_012100352.1|2567210_2567762_-	sigma-70 family RNA polymerase sigma factor	A0A0A0RUJ6	Bacillus_phage	3.0e-12	28.7
WP_012100354.1|2568121_2568973_-	ORF6N domain-containing protein	X5JAW6	Clostridium_phage	1.0e-67	51.5
WP_014519351.1|2569272_2569470_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012100357.1|2569761_2570139_+	helix-turn-helix transcriptional regulator	A0A2H4J076	uncultured_Caudovirales_phage	3.4e-20	50.8
WP_041173165.1|2571707_2572970_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_012100360.1|2573020_2574451_-	adenylosuccinate lyase	NA	NA	NA	NA
WP_003395736.1|2574688_2574910_+	DUF378 domain-containing protein	NA	NA	NA	NA
WP_003362134.1|2574937_2575195_-	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_012100361.1|2575305_2576499_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_004440581.1|2576643_2577000_-	EamA family transporter	NA	NA	NA	NA
WP_004440270.1|2576996_2578280_-	membrane protein	NA	NA	NA	NA
WP_004440805.1|2578298_2579165_-	decaprenyl-phosphate phosphoribosyltransferase	NA	NA	NA	NA
WP_003362540.1|2579328_2579589_-	stage V sporulation protein S	J9PTX7	Bacillus_phage	1.6e-08	39.8
WP_012100362.1|2579727_2581269_-	ribonuclease Y	NA	NA	NA	NA
WP_012100363.1|2581503_2582562_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.4e-119	63.5
WP_003362543.1|2582709_2583294_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_012100364.1|2583277_2584615_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_003388321.1|2584709_2586986_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	1.8e-87	49.7
WP_003388341.1|2587466_2588159_-|protease	Clp protease	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_017297|3093288:3102891|DBSCAN-SWA
TCTAGTGTTTAAAATGTCTTATTCCTGTAAATACCATAGAAATCCCTTTTTCATTACATACCTTTATAGATTCTTCATCTCTTATAGAACCGCCTGGTTGAATTATGGCTTTTATTCCCCATTTTGCAGCTTCTTCTGCTACATCTCCAAATGGGAAAAAAGCATCTGAAGCTAAAACTACGCCATCTCCAGCTCTATCTAATGCTTCCTTTGCTGCCCATATTCTATTTACTTGGCCTCCCCCAATACCTTTTGCCATACCATCTTTAACTACTACAATAGCGTTGGATTTCACATATTTAACTACTTTCATACCAAATATAAGATCTTTCATTTCTTGCTCTGTTGGGGATTTTTCTGTAACTACTTTTGTATCTTCTAATAATTTATTATCACTCTTTTGTACTAATATTCCTCCATCTACCTTTGCCATATCTTTTCCTTCTGTAGATTTCTCTTCACATTTTATAACCCTTAAATTTTTCTTGTTTTTTAAGACTTCTAAAGCATCTTCATCAAAATCTGGTGCTACAACTATTTCTAAAAATATTTTTGCAAGATTTTCTGCTGTTTCCTTATCTACTTTTCTATTAAAAGCAACTATGCCACCAAATATAGATATAAGATCACATTCATAGGCCTTAGTATAAACTTCCTGTACAGTATCCCCTATAGCCACACCACAAGGTGTATTATGTTTTAATGCACAACAAGCCACCTCTTCAAATTCACAAACGGTTTTCCACGCTATATCCATATCCTTTATGTTATTGTAGGATAATTCTTTTCCATTTAACTTTTCAAAATTTTTCATAGGATATTTTCCAACAGTAGATGTGTAATAAGCTGCTGTTTGATGAGGGTTTTCTCCATATCTTAAATCTATGTTCTTTTTATAGGATAAAGTTAAGTATTCTGGATATTCCTCTTCCAATAAGAAATTACTTATAGCTGCATCATAGGCTGACATTAGATTGAAAACTTTTCCTGCTAATTTTTTTCTAGTTTTTATATTAACCTGATCATTTTCTTTTATTTCATCTATGACATTTTCATAATCCTTAGTATCTGTTAGTACTACTACATCTTTAAAATTTTTAGCTGCTGCTCTTATCATAGTAGGTCCACCGATGTCTATAAATTCTACTTTTTCATCAAAACTTAAATTTTCTTCTACTTTGTTAAAGAAAGGATATAAATTCACTACTACCATATCTATAGGGTTTATGCCCTTTTCTTCTATTACCTTCATATGCTCTTCATTATCTCTTATAGCTAATATGCCTCCATGAATTAAAGGATTTAATGTTTTTACTCTTCCATCTAACATTTCTGGAAAACCTGTTACCTCTTCTATATCTATTACTTTTACTCCATTTTCTTTTAAATGTTTATAAGTTCCACCTGTAGATATTATTTCTACATCTCTACTTTCTAAAAACTTTGCCAAATCTAAAATTCCTGTTTTATCAAATACACTTATTAATGCTCTTTTTATCACTTAAACTCCCCCAGTTTCAATATTTTTTATTATCTTATTTATCTGTCATAAGTAACTGCCACCAATATACCTTCTTTCAAAGAAAACATATAAGTGGCACTATTTCAATTTACAAACTACAATTTTTTATATTTCAATAAATTTAATCTACTCTAAACACATTTTTCTATTAGTTTCATTTATATTAATAGTAATTTTTTCATTATTATAAATTTAGTATGTTTTAATAAAAACTTTTCTTCCTTGTAATTTTACTTTTCCTTCACTTATAAGTTTTATAGCTTCTGGTAATGCCTCATGTTCTTTTTCTAGAACTCTTTTTTGCAATATTTCTGCTGTATCTTCTGCAAAAACTGGTACAGATTTTTGTATTATTATAGGTCCACTGTCCGTACCCTCATCTACAAAATGCACAGTACACCCAGATACTTTTACTCCGTATTCTAATGCTTTTCGGTGCACTTTTATACCATACATTCCATCTCCGCAAAAGCTTGGTATTAATGAAGGATGTATGTTTATTATCCTATTTTCAAATTTATTTACCAAATCCCCATTTAATATAGAAAGCCATCCTGCTAAAACTATTAAATCTACGTTTCCATATAAACACTCACATATTTTATTAGACAGATTGCTTTTATATATTTTTCTATCTAGAGTTAAAGTTTTAATTCCCTTTTTTTCTGCTCTTTCTATACCATAAATATTAGATCTATCCCCTATAACCATTTCTATCCTGCAATTTTTTATATATCCTTCTTCTATTTTATCTATTATAGATTGAAGATTGCTTCCTCCCCCTGAAACAAGTACTGCAATTTTAAACATCCTATTCTCCTTTAATTTAAAGAAAATTTTTCATATATACTCTATAAATAATTAATTTCCCAATCAATTATTTTAAAGATCTAACCTATGAACTAATTTTTATTATAAATTTATTTAATACTCTTTTTTAAATTAGTTCAACAGACTTATTTCCTTTTTTTAACATATCCTATTTTATAACCCTTTTCTCCCATTTCTATCAGGTCTTTTATTATATTTTCCCCATCTTTTTCATTTACACATAATACAAAACCAATCCCCATATTAAAAGTATTGTACATATGATCTTCTTCTATCCCTAAACTCATTAAATGGCTAAATATATTTGGTAATGGATAAGATTTTTTATTTATAACTGCTGTAAAATCCTCTTTAAACATTCTAGGAATATTTTCATAAAAACCTCCTCCAGTTACATGAGCCATACCTTTTATATTATATTTTTCTAAAAGTTTCATTACAGGTTTTACATATATTTTTGTAGGAGTTAAAAGAGTATTTCCTATTTTATTTCCTTCAAAATCTTTATGTAAATCTTCTACTAATTTTCTTATAAGAGAATATCCGTTGCTATGAGGTCCTGAAGATGCTATACCTATTAATATATCCCCATCTTCTATTTTACTTCCATCTATTATTTCATCTTTTTCTGCTATACCTACAGCAAAACCAGCTATATCATATTCCCCATCTCTATAAAAGCCTGGCATTTCTGCTGTTTCTCCACCTATTAGAGCACATTCACTTTGGATACAACCATTGCTAACCCCTTCTACAAGCTGAGCTGCAATCTCTGATTCCAATTTCCCGCAAGCTATATAATCTAAGAAAAATAACGGCTTAGCACCATGACATAATATATCATTTATGCACATAGCTACGCAATCTATTCCTACTGTATTATATTTTTTCATTCTAAAGGCTATATCTAATTTAGTTCCAACTCCATCTGTACCTGATACTAATACAGGATTTTTATATTTAGGAAGTTCAAACATTCCTGCAAAACTTCCTAAATTATTTAATACTCCCTTTGTAAAAGTTTTGGAAGCATATTTTTTTATAAGATCTACAGATTTGTAACCTTCCTCTATGTTAACCCCAGCTTCTTTGTAAGATACCATGAATAACATTCCCTTCTTTAAATTATTAGTTATTCTACCAATAAAAAAACTATATTAAGTTATTTTAACTTTAGGATCATGAAAAAATAATCGATTAAATATGAATCGTATATTTAGTGTCAAACAAAGAAATAAATTTTTTCTACCTAAAGCTAGAACAACTTAAATCCTCTATTCCAAACTATCTTTAGGCATTTCTATAGGTGCAGATATAGGATATATACCATTAAAACATCCCAAGCAAAAGCCTTTATCTTTATTAAGTGTTTCTACTAAGCCTTCCATACTTATATAAGCTAGACTATCTGCTCCTATTTTTTCTCTTATTTCTTCTACTTCTGAGTGAGCACCTATTAAATCTTTTCTATAAGGAGTGTCTATTCCAAAATAGCAAGGATATTTAACCACTGGAGATGATACTCTAAAATGAACTTCCTTAGCTCCAGCTTTTCTTAATATTTGTACTAATCTTTTACTAGTAGTTCCTCTTACTATGGAATCATCTATTATTACTACTCTTTTTCCTTCTACATTTATTTTAAGTGGATTTAGTTTTACAGATACAGCTTTTTCTCTTAATTCTTGAGAAGGTGCTATAAAAGTTCTTCCCACATATTTATTTTTTATAAATCCTATACCATAAGGTATTCCTGAAGCTTCAGCATATCCTACCGCAGCTGGTATACCTGAGTCTGGGACTCCTATAACTATATCTGCCTCTACTGGGTATTCTTCATAAAGTTTTCTTCCCGCTCTAACCCTTGATTCATAAACATTTATACCATCCATAGTACTATCTGGTCTTGCAAAATATATATATTCAAAAGCACAGGTATGACATTTTGTTTTTTCTGTAAACTTAATTGAATTTATTCCACTTTCGTCTATAATAACTATTTCTCCAGGCTCTATATCCCTTATAAACTCTCCACCTACACAATCAAAAGCACAACTTTCCGAGCTTAATAAATAATCATCCCCAATTTTTCCTAGGCACATAGGCCTTATACCATGAGGATCACGTGCTCCTATTAACTTATCTTCTGTAAGTATAACTATAGCATAGGAACCTTTAATTGCTTGTATTGCATCTACTACTGCTTTATCTATACCTTTTTTAGCGCTTCTTGCTATTAAGTTTAATAATACCTCTGTGTCTATAGAAGTTTGAAAAATACATCCGCCATCTTCTAAAAGTTCTCTTATAACTGCTGCATTAACTAAATTACCATTATGGGCTATAGCAATAGAACCTAACTTATAAGTACCTACTATAGGTTGTGCATTATCTGATTTACTCGCTCCTGTAGTTGAATATCTAACATGTCCTATAGCAGAATTTCCTATTAATCCTTCTATAGTTTCTTTGCTAAAAACATCTGATACAAGACCCATACCCTTATGATATTTAAACTTTTCTCCATCAGATACTACTATTCCTGCACTTTCTTGTCCCCTATGTTGAAGAGCATATAATCCGTAATAAGTTATTTCTGCTGACTTTGATTCATTATCTTTAGAAAATACTCCAAATACCCCACATTCTTCTTTAAACTTATCTCCTTCTAAATCAAAGGGCATATTTTCATTTAAATCATCTAACATATAGCACATACTCATTTTTACTCCCCACTTATTTTCTATTTTAAAAATTTAATCTTCTCTTAGATTATTTCCAGCTGCTGTAAAAATAATTTTAAACTATAACAATCTATTTATTGACTCTTTTTAATATTTCCATATAAGCTTCTTTTACATTTCCCATGTCTCTTCTAAATCTATCTTTATCTAACTTTTCTCCTGTTTTTTTATCCCATAATCTACAAGTATCTGGGGATATTTCATCTGCTAAAAGGAGCTCACCATTAAATCTTCCTATTTCTATTTTAAAATCAACTAAATTTATTCCTTGCTCATCAAAGAATTCTTTTAATGTATTATTTACTTTTTCTGCTATAGAATACATTTCTTTTAGTTCTTCAAAGTTTGTAAGTCCTATAGCCACTGCATGATAGTCATTTATAAGAGGGTCATTTAAATCATCATTTTTATAACTTATTTCAAATACAGTAGTATCTAATTTTCTTCCTTCTGAAAGACCTAATATTTTTGCCATACTTCCTGCTGCTATATTTCTAACTATAACTTCTAGTGGAACTATTTCTACTTTTTTGCAAAGCTGTTCTCTTTCATTTATCTTTTCTATAAAATGTGTTTTTACGCCCTTTTTTTCTAAAAGTTCAAATAACATTGCCGTTATAGAGTTATTCATAACTCCCTTATCTTCAATAGTTCCTTTCTTTTCCCCATTAAAAGCTGTGGCATCATCTTTATAATACACAACAACTGTATCCTTATCATCCGTTCTGAATATTTTTTTAGCCTTTCCTTCATATAACATATCCTTCTTTTCCATTATAACTCCACTCCCTCTTTGTTATCATTTATAAATTTTTCTTTCATATCTTTTCTATATTCTATAAGTTTTTCTCTTAGCTTTTCATACTTTAAAGATAATATTTGTACCGCAAGCATTCCTGCGTTATAACTATTATTTATACCCACTGTAGCTACAGGTATAGATTTAGGCATTTGAACTATAGATAAAAGTGAATCCATTCCTCCAACTGCGGCTTCTATAGGCACTCCTATAACCGGAAGAATCGTATGAGAAGCTATAACCCCAGGTAAATGTGCTGCAAGACCTGCCCCAGCAATTATACATTCATAACCTTCCTTTTCTAAATCTTCAATTGTTTCCATCAACTTTTCTGGTACTCTGTGCGCTGAAAGTATGTAAGCTTTATATTCTATACTAAACTCTTTTAAAGCTTTAGCCGCTCCCTTCATTTTATCAGTGTCAGATTTACTTCCAAAAATAATAGCTACTTTCATGTACTAGACCTCCTTATATTTAAATATATAAAAAATTCCGCTAAGATTTCTATGGAGAATCCTAAAGCGGAACTTAAGCGCACTGCAAAAGCATAGCTAAGATTCATCCATAGACAGGGAATTTATGGTTCCCTCGTAGAGACTCTCAAACCTTATTATTGAGATTATATGGATGATATATTCATTTGTTTTATGTACTCATGGTAACATATAATACTTAATAAATCAACATGCTTTTATAAAAACATTCGTATTTTATTGGTATTTTATTTATTTTTTCGTAATATCATTCGTAATGTAACGAACAATTAGTTAAGTCAGAAATTCACTCAAATATATAATATATATTATATTGTAATAGAAATAATTTATAATAGAAATTTATTTCTGAAAATAAAATAGATTTAATTTTAAGATATCAAGCAAAATAATATATGGTAATAAACATATGAATAAGCTTTAACATTTTCTAATCTTTTTAAATCGGGAGCTTTTGTTATTAATCAAAGAATGAAGGTAAAAAACCGATGGCCAAGCCACACATAGCTTTTCCATCGGGTAAAAAATTTTTAATGAAAAAATTTGACACTCCTAGTCAAGTAAGTTATCTATCTATACGTGTATTTTTTATATTTGCATGGTTAAAATTAAGTCTATTTTAAAATAGTACTATCTAAGATAATTATTTTTTTCTTCTATAAGCAGTATCCTCAAGTGGAAGTTTTTTTCTAAATTCTCCATCAAATTTATAATACGCTCCTTGAGAGGCTGGCGCTGTTGGTATGGTTGTAATTTCTCCTATTCCTTTTGCACCATAAGCTAAATCATTAGTATTCTTTTCAATTATTGTTGTTTCAATTTCTGGTATATCAGTAGCTCTAAACAAACCTAATGTGCCAAATTTAGCAGTTGGGATAGATTTATTTAATGGATAATCTTCTGTAAATGCATACCCAAGTCCCATAACTATTCCACCTTCAATTTGTCCTTCTACATTAGTTAAATTTATAGCTTTTCCCACATCATGTGCTGCAACTACTCTTTCTATTTTTCCATCATCATCAAGAATAACAACTTGTGTTGCATAGCCATAAGCCACGTGACTTACTGGATTCTTTTTATCAGAATTAATAGGATCTGTAATACTTTGATATTCCCCATAAAATTCTTCACCTTCACACTCTTCTAATGATGTAGTTAATAATTTTTCCTTAAGCTTTAATGATGCCATTCTTGTGGCTTCTCCAGTAAATACTGTTTGTCTTGATGCTGTAGTTGTCCCTGAATCTGGTGCAAATTTTGTATCTGGTAAATCTAAAATTATCTGTTCTGGTAATAAACCTATTGTTTCACATATTATTTGTGTAAGAATTGTTCCAAGACCTTGACCTATGCAAGCTGCACTAGTTCTTATATGAACCTTTCCATCTATTACTATTAAGTTACATCTTCCAATATCCGGTATTCCAACACCAACTCCTGAGTTTTTCATACAACAGGCTATTCCTGCACATTTACTCTTTTTATATACATCTTTCACAGCTAATATAGTTTCTTTAATTGCAGTTCCTTTATCAGCAATTTGTCCATTAGGTAGTGCATCTCCAGGTTCTACTGCGTTTTTAAATCTTATTTCCCAAGGAGATATACCAACTTTTTCAGCTAAAAGATTTAAGTTGCACTCTGATCCAAAAACTGATTGTGTTACTCCAAATCCCCTAAAAGCTCCTCCTGGGGGATTGTTAGTATATACAGCGGTACCTTTTATTTTCACATTAGGGCATTTATATGGGCCAGCTGCATGAGTACAAGCTCTTTGAAGTACAGGTCCTCCTAATGATGCATAGGCACCAGTATCTGATATAATATCTGCTTTAAAAGCAGTTAAATTTCCTTTTTCATCACATGCAGTAGTAATTGTCATTTCCATAGCATGTCTTTTAGGATGAATCTTTATACTTTCCTTACGACTTAAAGTTATTTTAACGGGCTTTTTAATAGTCCATGCAAGAAGAGCGGCATGATGTTGTACACTCATATCTTCTTTTCCACCAAAGCCTCCACCCACATATTTGCTAATAGTCCTTACTTTTTCTTTAGGAAGCCCTAAAAGCTCAGAAATCTCTCTCTGCTCATCATATATGCCTTGGCTTCCTGTATAAATAATAACTCCATCCCCATCTGGCATAGCTAAAGCACTTTCAGGCTCTAAAAAAGCATGTTCAGTAAAGGGAGTAGAATAATGATTAGTAACCACATACTTAGAATTGGCTATTGCCTCATCTACATCTCCTCTATTAACTTTTTCCACTGTTAAAATATTTCCCTTAGGATGAATTTTAGGAGCATCTTCAGCTATTGCAATATTAGGATTAGAAATAGGTTCTAATTCTTCATATTCTACCTTTATTAAATTAAGTATTTCTTTTAAAGCCTTCTTGCTTTTTGCTGCCACTAAAGCCACTGCATCACCAACATACCTTGTTTCTTCTCCTACGGCTATCATTGCTGGCCAATCCTTTACAATATGTCCTATAAGTCTATTTCCTGGGACATCTTCTGCTGTAAGAATAGCTTCAACTTCTGGATGTTTTAAAGCTACACTTATATCAATGCTTTTTACTAAAGCTCTAGGATATTTTGATCTTAAAGCAGAACCATAAACCATTCCTTCTATCTTCATGTCATCTACATATTTTCCTATACCTAAAATTTTATCTTTTGCATCTATTCTTGGAATATTTTCACCTATTTTTCCTTTATATTCTTTCGCAAATGGAAGTTTACCATTTCTAAATGCCTCTGCTGCCATTTCAATGGCTTTTATTATTTTCACATATCCAGTACATCTACATACATTTCCTCTAATAGCAGTTTTAATTTCTTTCTTATTTGGATTTAGATTTTTATCTAAAAGTGACTTTGCACTTATTATCATCCCTGGAATACAATATCCACACTGTACTGCTCCAGCTTTAGAAAAAGCCCAAGTAAAAACATCCTTTTCAAATTCTGTTAACCCCTCTACAGTCTTAACATCTTTTCCATTCACCTTTGCAGTTGTACATATACAGGCTCTAAGTGCCTTACCATTAACAAGTATCATACAGGCTCCACAGGCTCCTTCTGCACACCCATTTTTTACTGAAGTTAAATCCTCATTATCCCTCAAATATTCAAGTAAATTAATATCCTCTGAAACAGATACATTTCTTTCATTTAATATAAATTCATACACATTTATTACCCCCAT

Protein sequences of DBSCAN-SWA_4

>NC_017297|3093288:3102891|3095001_3095619_-|WP_012100666.1|DBSCAN-SWA
MFKIAVLVSGGGSNLQSIIDKIEEGYIKNCRIEMVIGDRSNIYGIERAEKKGIKTLTLDRKIYKSNLSNKICECLYGNVDLIVLAGWLSILNGDLVNKFENRIINIHPSLIPSFCGDGMYGIKVHRKALEYGVKVSGCTVHFVDEGTDSGPIIIQKSVPVFAEDTAEILQKRVLEKEHEALPEAIKLISEGKVKLQGRKVFIKTY
>NC_017297|3093288:3102891|3099158_3099638_-|WP_012100670.1|DBSCAN-SWA
MKVAIIFGSKSDTDKMKGAAKALKEFSIEYKAYILSAHRVPEKLMETIEDLEKEGYECIIAGAGLAAHLPGVIASHTILPVIGVPIEAAVGGMDSLLSIVQMPKSIPVATVGINNSYNAGMLAVQILSLKYEKLREKLIEYRKDMKEKFINDNKEGVEL
>NC_017297|3093288:3102891|3100165_3100300_+|WP_041173178.1|DBSCAN-SWA
MAKPHIAFPSGKKFLMKKFDTPSQVSYLSIRVFFIFAWLKLSLF
>NC_017297|3093288:3102891|3098454_3099159_-|WP_012100669.1|DBSCAN-SWA
MEKKDMLYEGKAKKIFRTDDKDTVVVYYKDDATAFNGEKKGTIEDKGVMNNSITAMLFELLEKKGVKTHFIEKINEREQLCKKVEIVPLEVIVRNIAAGSMAKILGLSEGRKLDTTVFEISYKNDDLNDPLINDYHAVAIGLTNFEELKEMYSIAEKVNNTLKEFFDEQGINLVDFKIEIGRFNGELLLADEISPDTCRLWDKKTGEKLDKDRFRRDMGNVKEAYMEILKRVNK
>NC_017297|3093288:3102891|3095765_3096743_-|WP_014519379.1|DBSCAN-SWA
MVSYKEAGVNIEEGYKSVDLIKKYASKTFTKGVLNNLGSFAGMFELPKYKNPVLVSGTDGVGTKLDIAFRMKKYNTVGIDCVAMCINDILCHGAKPLFFLDYIACGKLESEIAAQLVEGVSNGCIQSECALIGGETAEMPGFYRDGEYDIAGFAVGIAEKDEIIDGSKIEDGDILIGIASSGPHSNGYSLIRKLVEDLHKDFEGNKIGNTLLTPTKIYVKPVMKLLEKYNIKGMAHVTGGGFYENIPRMFKEDFTAVINKKSYPLPNIFSHLMSLGIEEDHMYNTFNMGIGFVLCVNEKDGENIIKDLIEMGEKGYKIGYVKKRK
>NC_017297|3093288:3102891|3093288_3094788_-|WP_012100665.1|DBSCAN-SWA
MIKRALISVFDKTGILDLAKFLESRDVEIISTGGTYKHLKENGVKVIDIEEVTGFPEMLDGRVKTLNPLIHGGILAIRDNEEHMKVIEEKGINPIDMVVVNLYPFFNKVEENLSFDEKVEFIDIGGPTMIRAAAKNFKDVVVLTDTKDYENVIDEIKENDQVNIKTRKKLAGKVFNLMSAYDAAISNFLLEEEYPEYLTLSYKKNIDLRYGENPHQTAAYYTSTVGKYPMKNFEKLNGKELSYNNIKDMDIAWKTVCEFEEVACCALKHNTPCGVAIGDTVQEVYTKAYECDLISIFGGIVAFNRKVDKETAENLAKIFLEIVVAPDFDEDALEVLKNKKNLRVIKCEEKSTEGKDMAKVDGGILVQKSDNKLLEDTKVVTEKSPTEQEMKDLIFGMKVVKYVKSNAIVVVKDGMAKGIGGGQVNRIWAAKEALDRAGDGVVLASDAFFPFGDVAEEAAKWGIKAIIQPGGSIRDEESIKVCNEKGISMVFTGIRHFKH
>NC_017297|3093288:3102891|3096914_3098363_-|WP_012100668.1|DBSCAN-SWA
MSMCYMLDDLNENMPFDLEGDKFKEECGVFGVFSKDNESKSAEITYYGLYALQHRGQESAGIVVSDGEKFKYHKGMGLVSDVFSKETIEGLIGNSAIGHVRYSTTGASKSDNAQPIVGTYKLGSIAIAHNGNLVNAAVIRELLEDGGCIFQTSIDTEVLLNLIARSAKKGIDKAVVDAIQAIKGSYAIVILTEDKLIGARDPHGIRPMCLGKIGDDYLLSSESCAFDCVGGEFIRDIEPGEIVIIDESGINSIKFTEKTKCHTCAFEYIYFARPDSTMDGINVYESRVRAGRKLYEEYPVEADIVIGVPDSGIPAAVGYAEASGIPYGIGFIKNKYVGRTFIAPSQELREKAVSVKLNPLKINVEGKRVVIIDDSIVRGTTSKRLVQILRKAGAKEVHFRVSSPVVKYPCYFGIDTPYRKDLIGAHSEVEEIREKIGADSLAYISMEGLVETLNKDKGFCLGCFNGIYPISAPIEMPKDSLE
>NC_017297|3093288:3102891|3100320_3102891_-|WP_079992192.1|DBSCAN-SWA
MGVINVYEFILNERNVSVSEDINLLEYLRDNEDLTSVKNGCAEGACGACMILVNGKALRACICTTAKVNGKDVKTVEGLTEFEKDVFTWAFSKAGAVQCGYCIPGMIISAKSLLDKNLNPNKKEIKTAIRGNVCRCTGYVKIIKAIEMAAEAFRNGKLPFAKEYKGKIGENIPRIDAKDKILGIGKYVDDMKIEGMVYGSALRSKYPRALVKSIDISVALKHPEVEAILTAEDVPGNRLIGHIVKDWPAMIAVGEETRYVGDAVALVAAKSKKALKEILNLIKVEYEELEPISNPNIAIAEDAPKIHPKGNILTVEKVNRGDVDEAIANSKYVVTNHYSTPFTEHAFLEPESALAMPDGDGVIIYTGSQGIYDEQREISELLGLPKEKVRTISKYVGGGFGGKEDMSVQHHAALLAWTIKKPVKITLSRKESIKIHPKRHAMEMTITTACDEKGNLTAFKADIISDTGAYASLGGPVLQRACTHAAGPYKCPNVKIKGTAVYTNNPPGGAFRGFGVTQSVFGSECNLNLLAEKVGISPWEIRFKNAVEPGDALPNGQIADKGTAIKETILAVKDVYKKSKCAGIACCMKNSGVGVGIPDIGRCNLIVIDGKVHIRTSAACIGQGLGTILTQIICETIGLLPEQIILDLPDTKFAPDSGTTTASRQTVFTGEATRMASLKLKEKLLTTSLEECEGEEFYGEYQSITDPINSDKKNPVSHVAYGYATQVVILDDDGKIERVVAAHDVGKAINLTNVEGQIEGGIVMGLGYAFTEDYPLNKSIPTAKFGTLGLFRATDIPEIETTIIEKNTNDLAYGAKGIGEITTIPTAPASQGAYYKFDGEFRKKLPLEDTAYRRKK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012100665.1|3093288_3094788_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH	Q58MG4	Prochlorococcus_phage	1.2e-68	47.5
WP_012100666.1|3095001_3095619_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.4e-25	40.1
WP_014519379.1|3095765_3096743_-	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	5.7e-67	42.9
WP_012100668.1|3096914_3098363_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.2e-58	35.1
WP_012100669.1|3098454_3099159_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SLB8	Cyanophage	3.0e-41	43.7
WP_012100670.1|3099158_3099638_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.7e-27	49.4
WP_041173178.1|3100165_3100300_+	hypothetical protein	NA	NA	NA	NA
WP_079992192.1|3100320_3102891_-	selenium-dependent xanthine dehydrogenase	A0A0P0IVM8	Acinetobacter_phage	5.8e-10	33.1

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NC_017297|3253962:3275563|DBSCAN-SWA
GCTAATAATTAATTTTAATATCTCCACTAAATTTACATTCTACTTGTAATAATGTGTTGCTAGCATAAATAACTTCATATAAATCTTCTTTAACTTGTTTCCATCTTCCAACACCATCATATTGCAAGTCAAGTTTATCTATCTCTTCAATATCTGTTATACTGTCCATACTAAATAAATAAGCAAATCTAATCTTTTTAGTAGTAACTAATTCATTCCAGAACACATCATTAATAGCATTAAAAGTAGCAATATTCATCCCATTTTTCCTTACGTCATCTACAGTTAAATTAACGTTCACCCATTTTTCTCCACTAAAAGTCTTCCAAGTATTACCGCTATCCACACTACAAACTATTCTTATATTGTTACCATTAGCAGTTAACCTAAAATAATCTATATGATCTACATTACTTAAATTCATATCACCTTTTGGAATAAGCAAACGATCAAATGGGATAGCCTTTGTCTTTAATTTTTGAATAACTCCATCTTCAAATGTTTCAAAACCTCCTATTTTTTTAAATAGCGTTTTATCCACATTAACACTATATTCTATAAAGCTTTCTGTATCTTGAACAACTTCAAAATCACTTATATGATTTGTTTCTAAATGTGCTTTACCATCAAATGTCATCATTTTATCATCAATAAAATCATTACTCTCATCATTAGTAAATTCGTTTTTAACTGATATTAAATCCTGTGTATTTTCTGTATCATATCTCAAAACATTCACACGAGGCACTTTAAAATCTACTGTGTTAACAGGGATGTTAACGATTCTAGGTGTTTCGGCACTTCCCACTATACCCATTTTAGATATTTGTTTCATTCCTGCGCCAACTATTTCTCCTGCATCTATACCATCAATAGTTGTAAACTTTCCTGTTTCCTCTGAATAAGCTACTAATTGTTTGTTTTTCTTATTAGTTACGTCTACATCCTCTAGCTCCTCAAATTTTGTAATTCTTTTATTTATTATTTCCTTTTGTATTTTCTCACTTGACCATCCAGTTTTATTAGAAATTACACTATCATCTAAAATTATATCCTTGTCCAAGGTTACATTAAAAAATTCACTCATTAGGCCACCTCCTATTCACTGACAACTAAATGAAAATCTCTAATTGCAAAATTATGATTTTCTGCATTTTTAGTTATTTTTACATATATCCCTTTACTTTCACACTGTTTTATACTATTTATAGTTAAAGAGTCTGTATAATTTATACCATCGAAGGATAGTTGTATTAAATCATTACTAGGTGTTTTAGTACCTATTTTAATATTGTTGTAATCCTTATTCCCTATATTTTTAATTGTTATTAGCTCTTCTAAATCCTGGAGCATAGCAGGACTAACATTGGTTACAACATTTCCATGATATATAATTTCAAAATTATATGGGCTAAATACCCACATATCACCATATTGTAATTGAAGAACATCACTAGTATATATCACTTTTCCATCCGTATCTTTAAATGTAAAATATGCCATCATGTTACCATCTATAAAAACTTTACATTCCATATCTGAATTAAATAATCTAGTTTTAATTAAATTATTATCTAAATCATATAATTCACATAAAGTATTTTCTGGGAAATTCTCAATAGTTACATAGGGATTAGCGTAAACCTTGTAATTATTTAATATAAAATCTTCATCACTATACTTCATAAAACCTTGCTTTGTAAGTGGCTCTATAAATTCCATGCCACCTATATTTATATAACTTTTACCATCATTACTTGAATAAGCTTGTATATAATTATCTTTCTTAAGTATTTTCCAATATCTATTTTGTTCATTTGATTTTAAATCCTTAATACCAAAAATATGATTGCTATTCCCTAAATAAATCATAGAATAATCCATATCTTTTATATCATTGAAATTTTCTTTTTCAACTTCAAGAACAAATTCTTTATAATCAAATTTTCTTTCCATTTTATTATTACTTATTAATTTTAATTTACCTGCTTTAATGTCTCTAGTTACATTACTTTCTCCTGCAAAATCAGCAAAAGAAGAAGCCAAGAAAAAATTCTCAGCTTCTAATAATCCATTTTTAACTTGTATAAGTTTCATTGAGATCACCTCTAAACTCTAGGCTGCATTATATAATCATATGGTACAAACTCAACTATTTGTATATCTTTAGTTCCTATACCATTTGCTAATAATGTATGTGCTTCCTCTAGTGCATCTTCATAACAATTAGTAGCGTAAGATGTTATTTCACTTCCATTTTTATCTGTTTCATGGCCGTATGGTAATTGGGCTAAGGTTTTATTTTTTAATATTCCCCACATCTTTTGTCTAGTTTTTTTAAAATCTATTGTACTTGTTAACATACTATCTACCTCCCAAATATATTTTTCTTTTCAAAGTTCTGTGTTTCTATCATGTAATTTCTCTTACCTTTTAGTTTATCTAAATCTTTCATAATATCACCATTAGTTGCTACTTTATTAAATTTCCTTTCAATATCCATAGCTTTCGGATTATGCCAAATTGGTACTAAATTAAAATGATGTTGTTTTAGATAATCTATTAAATTAGCTATAAGTAATCCTATAGCTTGTAATCCATTTTCAGTATTAAGGAAGTATACCTTTTCAGCCTCCCACCTGATCCATCTATATGCTCTAATATAATCTGCATTTGGACTTGATGTATCTAACGTATACCAATCATAAATTAATTCCATTATAAATTGAATAGATTCTTTGCCTGTACAGCTTAACCAAGCTTGTGCATTCTTATGCCATATCATCGCTAGAATGTTTATTAAATCTAACATTATTTCAGTACTAATTGTCATAGGTGGAATATTATAATCCACTCCCCAATCTTTTCCCCATTCAATAGGATGATTACTAAATCTTAAATATTCATAATCTAAATTATTTAATAGATCATTATTATATATATAATCTTTATTAGGAACAATTAGCCTATCCGTTGGATTTGTAGGCTTTAACCACCACCATCTTTTGGTTATTTCAATAAACTTATTTTTATTAGGTGTATATATTTGTCTTATAGCTTCATTATTTAAATATTTATTACTTTGTCTATAAATTTGCCATATACTTAAATTTAATAAATCTCTTTCTATCTGCTTATAGATATTAATTATAGGGCTATTATCTAAATATTTTTCTTTATGTTTAAATATATTAGTTGTATATTCCCTATCTAAATATCTATTATTATATTTAAATATAGATCTTATAGCTTGCCTATCTAAATACCTGTTGATACTTTTATCTATAAATTTAAATACATCTTTATAAAAATATTTTTTATTATGGTCTTTGCATATTTCTTTATGTTCTATTTTATTTAATGTATTTTTAATTCTATATTTTTCTATATCCTTTAGAGCTATATTATACATTAACATGGTTTTATAATTTCTATCTATATCTTTTAAATCTAATATTTTTAAATTGTTTATACTTGTATCTATATCTATTCCAATTATAATATCTTTGTTTAACATTGTTTTATTACTCATTTTAGCTGCTTCTTTTAAATTACACTTATCTATAAATCTATAATTGTTTTTATTTATATTTTTAAATCCATGTTTCTGAACAAACTTCGATTTATCTATATCTATTTCCTTGCAATAGATTCTATAAAGATAATATCCAATATTCTTTTCTATATTTATATACTTCTCTAGTTTTAAATTTTGTAAAGATTCACCTTTAAATATTTCTTTTTCTACTATTGAATCTGTATATATACTTTTGAATTTATTCAGTTGTAGATTTTCTCTATCTATAGATAAATTTATTAAATTATTAGCTTTATTTAGCTGCAACATTTCTCTTTTCAATAACTTATTGTTATAGCATATGGATATATCTGTATTTTTTCTTATATCAAGTTCCTTACTTGTTTTTCTATTTATACCTATATCTTTTATTTTATCTAAAGATATAGCATTGTTCTTATTTATTTCTTTATTTCTTAATTTTAACTCTTTTTCAAATTCTTTTTTTATATCAGTAATTTCCTTGGATATATATTTATTCTTTTCTTTCTCTATATTATCTTTAGGTTCCTTATAAAATAATTTATCTCCTTTAATTTTATCTATTTCACTCATTGTTTCTTTGTAAAATAATTTTTCTGTAGTTTTTGCTACTTTTTCTGTAGTATCATATATAAAAGTTCCACTAGAAAAAGTAGTATCCCCTACATATTTAAAACTACATAGGGGTATTTTATGTAGGGGCATTTATACCACCTCTCTTACTTAGTTGTTTTATAACATCTAATAGCAATACAATAATTTATATTAGCACTATTATTTAAGAAACAATATGGTGCAGTAATTTTAAATTTCTTATAATATTCTTCCTCTTCTGTATCTTTCTTATATGCTAATCTGTCAGTATCATTTATTGCACTAGCATCACCTACAAGTACATTAATCATTTTACCTCTTTCCATATCAACTGGATGTACAAGTGTTATATCTGAGAATTGATGTTTTTTATGGTTATATCTACTACCTTCTACATTACATTTATCCATAAAAGGATTAGTAGCATAAAAAGCTGGATAATGCGGTTGATATGGCATACCTATTTTATTAGCTATCATACAAACATCTGTTACTCCTGTTGCAGTTCTTTCTCCATAAACCTTTGAATAATTTGGTTCTATATCAGAAGATACAGTTATACCAAAATTATATTTATCATCTGTATAAGCTGAATCCTCTACTGGTTTTAAAGCTCCAATATAAGCATAAGATGTAAGATAGTTTTCATAAGGATGAACATCTGCAGATGGATCTCCACGTAATACTAAATTTATACTATCTTTAGTTACATTTATCCAATATTGAACTGGTAAAAAGTCTTTTATTTCTGGTTGTAATTTCCTATACCATGCTAATCTATAATTATATTCAGATTGTATGCTTTTAGATATACCTAAATCAGTTCCATCTCCATTCAATTTATCAGATATCTGTAACCTTATATTATTTATAGAATTGCTTTTAGTCATAGCACTAACATATGTGGTATATAGCTCATTGTTACCTGTCCCAGAGCTTGCACCCTTTGTAGGAAGCCCAGCCATATATTCTAAAGTCTCTGCATCTGTTCTATTACTATAATGACCATCTCCTATATAATAACTATGAAGTTTATTAAAATTCACTATTGCCTCCTTTTCTTCTTTTGTTAAATCCTCCTCTTTTCTATCTATTTTTAGGTAAAATTCTTTTCCATAGGTTGTTGTTGCTTTTATAATACACTTATCATTTTGAGAACCTATTCTAAATACAGTCTCTACTTTATCTGTCTTAGAATTATCTGTTATAAGATTTATTGTACTTCCTTCTCCTGTCGATCCTATTTTATCTATACTATCTGGATAAACTAAATCCCATTTATATATACCTGAATTTTGTGTTATTTCAGTTACTAAAGTTTTTACTAAATCTTTTACACTTGAATTACCTTCAATAAAATAAAAATTATCTGTAGCCATTTTATCTACCTCCTGTTATCAATTATTTATTTAAATTTGTTATTTTTAAAGTATTTAAGTCCATTATAAATATATCTTTTAAATCTCTATTTGTATCTAAATTCACATTAAATTTTTTAAGTAGTTTATTACCATAAGATCTATATTGATATATTTCCAAAGTTACAGGTTCTTTTAGTTCTACTCCATTAAAATTCTTTATACTTATAAGAAGCTTTTTATTTTTGTACCCTTTAACACTTATTATTTCAGGATTTTTATTTGTTTTATGACTTGTATAATCAAAATTAAGATAAAATCCATCATAGGATTTATTCCCATACCAAACTTTTTTACCATCTATCTCGCCATGCAAATCTATGTCTGCATCTGTATTTTCTTCCCAATTCATTACTACCGCTATATCCCATTCATTATCTATATCCTCTATGCCTGGTGTAATACTAGAATCTTCTCCATCTATATACTCTAAATCCACCATTGTTTGTCTACTATTGCCGCTTAAATTATGAAAAATAAAAGAAATAAGAGTATTAGCATTTACTTTATAGAATGTATTAAAGTATTTATGCTCCCCTATTTCCTTAGTTGTTGCATTATCTATTATTTTGATTTTATTAACTTCTAAGCTAAATCTGTCTTCCTTTTTCCATCCTGTTTGATTAAAATGCAATCCTGTAATATATACATCTTTATCAAATTTAAATTGTTCCGTATAATTATTTTGTATTGCTGGGATATCTAATAATATACCTTTCACTTTTTGAATACCTTCAATTTTTCTGTATATAAAAGTATCAATTTTTTTCTTTAGCCCTTCATATTGTACACTTGGCAATAAATCTTTTAACTGTTGTAGTAAGTCTTGTATATTATTAGTATTTATCTCTGGATAATTAGTTCTTATATTATCATCTATGAGACTTAACAAATGATTTTTCAAATCTTCTGTAAGTTCTTCAAAATTAATTATATATTTAGGTAAGCTCAAATTAAGCACCTTCTTTATATTCAAAGATTGAACTTGTATCATTTCTTGGATAAACTTGAGCTGTTTGTGTTATCTTTAAATAAGGGTTCTTAATATTAAATTCATCATAAAAATGTAATACACTTTGATATAATTCTTCCAAAGTTACAATTCTATTTTTATCTTTATCAGATTTCTTAGTTTTAATGCTTTGTGTTAATGCCCATGTAAAAGCTCCTGAAGGATTAGGATTTCCATTATATCCAGCGCTCAAGTCACCAGATGTTTCTGAACCTGCACTAGCTGTTAAAACCTTATATCCTTGTTTATTTAATGTTTTGTCTATACTTCTAAGTTTCTCCTCCACTACAGCTAATGTATATGCAAAATTTTTATCTATAGCAAGTCCACTGTGGCAAGTATCAATAAATATTACTTTAGTACCTTTTATATCATCCAGTATTGTTTGTAATTCATATACTGTTATTATGTTATCTTTTGCTACTAAAGCAAACTTATCTTCATATACAGTACCATGTCCAGACCAAAACAAATAACTAATATCATTATCTTGTGCATCTTGAAAAGTGTTTTTTATTAAATTTAATGCTTCTGACTTAGTCTTATTTTTTGCAACTATATTTTTTGTAAATTTAGCACTTTGTTTGTGTTCTTTAAATAAATTAGACATATTGTCAGCATCATATGTGCAACCCATAAGGTTATTAGCGCCTTGTAAAGTATATTCACTTTCTCCTATAGCTAAAAATCTATAGTTTTTTTCACTAGTGGTAGGTATAGTAGGTGTAGTAGGTGTAGGTAAATTACTATTTTCTAATATATTAAAATCTACCCATAAAACTTTACTAGTTCCACTAATATTATTGTAGATAAATTTAACTGTGCCATTTATAGGATAAAATACATTTAAAAATTTATGTTCACCATATTCTTTAGTGCGTACACTTTCAAATAATTTATCATTACCTACTTGTAAATCCCAGCTATCTTCAAATCTCCAACTAGATTGAGAATATGTTATACCTGTTATTTGTCCATTTCCCTTAAATTCTATTATATGCTGTCCTTTTACTGCAGGAATCTCTAGCATTTTCCCATAAATTTTCTGTGTGCCTGATATACCTAAATTTCCACTTAAATTATCTAACTTTACACCTAAAGCATTTAACGCATTTATTAAATCATTATAATCTACACCTTGTATTTTATCTTTAATTTCTGATAATAAATTTTCCATATCTTTGGTAGAAAAATTTATATTGCCTATGTCAACTTTCACACCATTTTGTAAATAATCCTTAATAAGATCTGATAGTTCATCAAAGTTGACTACATAGGAAGGTAATTCCATATTATTGCCACCTCCTATACATAATCTATTGTTTCTAATTTACCATGATTATCTTTAATTAATTGTATTGTTTTATTTGTATTATTAGGGTATGTTGTTTTAATTCTATATACTTTACCTTCTGCATTTCTAATTAGTTCTTCTTGCCATTGCATATCTGTTCCACTAGCATATATAAACTTATATGCCTTATTATTACTATCTCTAATTATTCTACATGGATATTCGGGTAATTCCCCAGTATATTTTGAATCTTCATTTGTATTTATTTGATTTTTGAAATTTCTTTTTCTTAATTCTTGATCTAAAATATAGACTACTGGTTTCCTAAAATTTTTATATCCCATATGTGCCATTTTAATCACCTACTATTGTTTCAATCTTCCACTGCCTATTTGGATACATTGATCATACACTTTTGTTTTATCTCGCATACCTTGTAATTGCAATGTATCTACATATGTGTCAGCATTTATTTCTGTACTTATTCCTACAATTAAATACCAGCCATTACCTCTTTGATTATTTATTAATTTAACTACTTGTCCTAAATCAATATTAGGTATTCCAGCTACTGGTACTACATTTAGGGCAGTACTCTCTCTCCACATATCTAAAAATTTATATCCTGCTACCTTCTGTTTTAATAATGGAGTACTAGCTAATGGATTATCAATTATATCTACCCATCTTTCACCATTTAAATAACTAGTCATAGCTTTAGATTCAAAAATAGAATATTTATCATTACAACAAATCTTTAATATATTTCTCATTAAATTGGAATCTCTGCTAGCAGTTTCACTAGATAAATTAGTATCAACAGATAAAACATAATCATGGTGATTTGCTTCATGATTTGATTCATTATAAGCAGGATATTGTTCTTCTAATATTATTGCACCGTTTTTGTTTGCCCTTATTCTAGCATACATAGTTTCTACCAAATTACTAATTATATCATTATACATAGTACCTATTTCACATTCTAATTTAGGCACAGTATAATTATTTCCTCCACTTCTTTGAAAACTACATTTAGCATCTGATACAACAGTAGAAATTATATCTGCTGCGGTTTTATTATAAAATTTTAATTCCTTATCACATAAATTTAACATTCTATAATACATATCATGACAAGTCATTTCTATTGTTTTATCAAGTGTATTATAATCATATTTTTTAATTACACCTGTAAATTGAAGTACATCCTCTATATAAATTTTTACCTGTGCAAAATTATCTATTATCCCTTGTATTCCTCCTGCAAAAATAGCAGTAGGTAGATTTTCATATTGTGCTGTAATCGTAGCTTCAGCAGTAGGCGTAGTTAAATTTCTATTTATTTTTACTGACACTAAACAATGTTCTAATGTTATTTTATTAGCATCACCATTTTCAAAAGCCTGATAGCCATTTTTTTTATAAAATTCTACTTTACACTTTGTCATTATCTTTCACCCATCCACTAGCTTCATGATTACATAAAAGCTCTAAATTTATATAATATATATCACCTTCGATAGGAGTATCTATCTCAAACTTATTTTGTAAATATCCTTTATATTGAATTCCAAATTCATCTATAAATATAAATCTACCTGAATAGTTTTTTCTAAAGTTTAAAAACTTAGTTATATTACTTTGTGTCTTCTCATCATTTTCTCCTTTTATATTAAAAGCAACTGTAAATTCAATAATGCAATCACTTTTAATATTTTTTTCAAAATATGTGTATCCTTGTACGGTTCTAATACCCTTGCGAAAATAAGCAGGACGAGGTGGCTTATAATTAGTTATTACGCCACCTGTATTTTTTCCATCTTGATAAAGCAAATCTACTTTAAAATCTTTTATTCTATTTAAGTCCATATAAGCCACCCCCTAATCTCTCAATACATCATTCATAAATAATCCTGTCATAACATTTTTCATAGAACTTTCTGTCATTTGTTTAAATTCATTAGCTATCTTATTAGCCCCTTCTTTATCTGCATTTGGTATAGTTACATACATTTTTATATCCTGTGTAAGTCCCATACTTTTATTCATGTTATTAGGTCCATATGGAGATGCATAAGTACCACCATATGCTCCACTAAGTGACATATTATTTAATCCATTAAAATTTGGTCTTACATTTCCTAATCCTTTAATTTTATTAGCTATACCTTTAAATTTATTATTTATGGCGCTTTCTTGATTATCTATACCTTGTATAAGACCTTCTCCAATAAAATTACCATAATCAGCAAATACACGTGATGGAGAATTTATACCTAACATTTTCTTAAATCTATTCTTTATTTCATTTGCTATACTCTCAATAGTCTCTCTCACTTTTTTTATACCTTCTTTGAGTCCACTTACTAATCCTCTCATAATATCCTGTCCTATTTTATGCATATATGTCCGGAATGCTTTCCATTTTATTTTCCATTTTTTTATATTTTTATCAAAATGGCCACTTATTTTTTTACATACGTTACTTATTTTTTTACCTAAATCATCCGCTGCTTTTTTTAACTGATCCCAATGTTTAATCACTTCATATACTATAAGTCCTATTGCTGCAATAGCAACTAAAATTAGAAGTGTTTTTGAAGTTATTATGGTCTTTAATAATCCAAATATCCCTCCAGCTTTCTTTAATTTACCAAATATACCTATCACATTATTTATAGTACCTACTAATTTGCTAAGTACCGTAAATGTTTTAGCAACTCCAGCTATTGACACAATTATTATTGCAATAGCGTTTTTTACAGGATTAGGTAATTTATTAAATGAATTCATTAATTCTACTGCTTTATTAGCTAGCTTTGTAAATATTGGGATTAATTTATTATTCAAAATAGGCACCAACTGATTATTAAATATCGGTATTAGCTGTTTTACTATAGATGCTTGTAACTGTGCAAAAGAATCTTGTACTTTTTTTATGGAAGCCTGTATATCCTTTTGAATTTTTTCATAGTTGCTTTTTGCAATATTAGCAGGGCCTTTTTTTGGATTCTTACTCTTTGCTTCTTCAGCAAGAGTATTTTTCATACCAGTTTTTAGAAGATTTTGTGCTACAGCACTGGGTTTCTCCATAGATTTTCCTATTTTACTGAAAGTCCCTGCTTTTTTGGCTAATGCTTCTTGTAATTTTTCAATTTTAGTTTTCTCTTCTTCAACTTTATGCACAAATATTTCTAAATCTTTTCCAGCTCCATTAAGTGCTTTTTTAAATTCACTAGTATCTAATGTTAAATGGGCAACTGCCTCTCCTACATTTACTGCCATGTTGTTTCTCACCTCCCACCTTTGGGAATAAAAAGTTTTCTAACTTCATTTAAATAATAATTTAAATTTAAAAATCTATTTTCTATTATTAGCATTTAACCATTGGATCACATCTTCATTATTAGTTTTATTTGTTCTATCTCCATCTATAAACTTAGGCTCTCTAGCATCTTCTTTACTAATCTCATTTAATATATAAACACAGGCCTCATCAAAACAAAAAGCCTCATAATCATTAGTCAACCCTATAACTTCACTGGGCCTTTGTCTATATTGTTTACTTATTGATATTACACTCAGTATTCTCTGACTCTTCACGAAAGGAGTCTAATTCACTAACACCTTCCTGTGTATAATTAAACAATGCTATTATTTGTTCATCTGTAAGCTCTAATCCTACACTTTTTAAATCTTCTATGGAAGGCTCTACAAGTGCATTTTCGGCCATAATATACATAACATCTGTCATTTGTGCTAAATCAATATTCTCTTTTGAACTCTGTTTACCATAAAATAGTTCCTCTGCTGCACTCAATAGCTTGTTAGGTACAACTCCTTTTCTTACCAAATTTAAAAGAGATACTCTTTTAACTCTAGCATTAAAAGGTATCCCTTGACCAAATTGTGGTAACTGAATTACTTCACCTTGAGCTACATTTTTTAAATCTTCTATATTAGTTACTTTTAAATCCATTTGTTATACCCCCACTATCTAATTTTTATTGTTTTAAATTCTGTGGATAATGCTGTAGTTTTACCACTTCCATCTAATTTATTTATTTCTTTAGCTTCAGCAATATAAACTGTATCTATTGATAAAGAATCAGGTACAAATGTTACTATTTTCTTAGTATCATCTATAGTTACATTTCCATTTACTCTAGAATCATCAGATTTTCTCTTTATAATAAAGTTTTCTAAGTTAACATCATCTTGATTAATTTGATTAGAAAAACTCCACACTACCCTGTTAGTTATACTTACCCCTACATCTGGATTGTTATTCTCTACTTTTCCACCTTCTACTCCTATATCTTCAATAGGAGTAGTCTCTCCTGGCTTTTCTCCATTATCATTTTCTTCTAATTTATTTATAAATTCTATTTCTACAGGTTTTTCATTTCTAAATGGTATACTTTCAGCCTCATATGAAGATACTAAAAATTTTCCATCTTGAATTTTATATTTTGCTGGCTTACCTTTACAATGCTTATACACGAACTTAACATATCCTGTGGTTCTAGAATAGTCTTTTTCTTCTGTGAATATTTCCATAGTGAATGGATGTCTTTCTACTGCTATACCTACTTCTGTTCCACAATATTTATTATCTTGTATAGTTCCTCCATCTATTAAAGCCATAGTTTCTATATTAAATAGATTGTCTTTCATTTTTAACTTGTAGCCTATAACAATATCATCTGTTTCATTTATTCCATAAATTTTGTTTTTAATCCTTAATATATCTCTTTTACCTTTACTGTTTATAGGTTCTATATCTATTTCATTACTTGTTTCTATTGTATGCTTTGTATTTGTTACCTCATCAATAAAATTAACTTTCACAACATTAACTAAAGTTTTTCCACTTGTCATTAAATTACCTCCTTAAACTTTTAAATTGCTGATATTCTATGCTTGTAGTATAGGCTTGTACATCATAATCTATAATGCTTGGTGTTTCATTTCCTGTAGGCCTAAGATCTTGTATTTTTTTTAAAGCTTCTTTTAAATTCTCTACATAAAATTCCATAGTGGAATATTGATCCATAGGGTTATAGACTATAATATCAAATAGTTTATAACCAGATATATTTCCAACTAAGGCATGAACACCATTTTCCTTTATAACTACATAGCTTTCTGTACATTTATTTCTCTTTTGTCCAGGAGCATACACATTATATCCTAATTTTTTTAAACATAAATATACCTTTTGCCATAAGGTTTCAGGTACAGCATTATCGATTATGTCTTGCTGTATGCAATCCCCTGGAACTTTGTAATTAAATTTAGACATTTATATCACTTCCCAAATAAATTACTCATCCCCTTAAGTATTTGTGGACTCAGTTTATCTATAGTTGGCTTTAATATTGCATATTTTTTATCATTACATAATTCTAAAGACGAATAGTAATCCTTATTTCCAGAAATATAAATATTACACTTATCGCCTTTCCATTGTTCTCCACCTTTAATTGTTTCAATATCCTTACCTGATTGCTCCTTCCAAGGTGCATTTTTTTTAGCATCTTCTTCTAGCTTCTTTGCGGCAATATCTGCATACCCACTTATAGCAGTTTTAGATTGCATCTCAAATTCAGATAATCCATCAATAACACTATCTATATTTACTTCAAATTCACTCATATCATCACACCCTGTTTAATATCATATCAAATACTAGGTTTTGAATATTTCCTGTGTCAACTATTTCATACTTAGTTCCATCTAATATAAAATAATCATCCTTTTGTATTTTAGAGCTTATATCATTATAGATAATTAATAATTTATCATTATATAAATTATTAAATTCCAGTCCTTCCATAGAAGTTGTAATTATATTACTATTATTTCTATAATAATATCCCTTTATAGTGCATACATACACTTCATCTAGTTTTTCTTCAAAAGCATTTTTACCTATTCTTAATATTTTTATTTCTCTTAATAAGTCTTTTTTTTCTAGATGTTCATATATATTTTTACTTATTTTTGCCCTATTTATATTATTCATTAATGTTCATCAACTCTTTCCATAGAAGTTTGATTCTTTAGAATCTTTTGCTCTTCTTTGAAATGCTCTGCTAGAGTTAACCAATAAGCTCTATTACTTTGTAACTTTATATCTGCAACTTCTATGCCATCATCTGCAATTGCTTTTAGAATACACCCTTTATAGCTTGATTTTTCTACATCATTATTATTGATTTCTAGTAGCAATTCTAGCTCTTTATCCTCAAAATAAGGATACTGTTTTTCTTGTAAATTAAATTTCAAAATCTCTAAAGGTGTTCTCACTTTTCTCACCTTCCTTAGTTAAATTTTATTTGTTTAAGGTTACTAATTTTTCTGCAAATATTTTCAATAATAGTTTAATCATTTACTTAGTCAACTTATTACATAACCTTAAATCATCCTCATTATGATAAATTATTAAATATAGCTCCCCCCTCTGCTTACTGTACAGCCTTTAAGTTTTCTTGAAATAAATAAGCATTAGATCTTATAAAAGCCTTAATTTATAACTTTATCTATAAGAAGTTATAAGAATTAAAACTTATTTTGCAAATCTAATGCATTATTTACGGATTATAAAATTTTTAGTTCAAATTATTCAGTTTTTTAGTTTACTCTTAAAAGCTGTAAATTTTAATTTGATTTCATAATATTCATTTATTTTTTAATGAATACTTTACAGTTGTTTTATACAATAAAACCTCTGCTATTTTTATAATACTATTATATTTCATTTGAATACTTTATTTATCCCAACTTTGTCTCATTTTTGTCCCAAAATATTTTTATACTATAAGGTTATTCAATTGTGCTACATGTTCTACTAATTCATTCTTTTTTCTATAAGCTGTACTCCTTGCTCTTCCAAACATTTCTACAGCTATCCAATCTACACTTTTATTTTCTCCATACTTTAACTCTATGAATTTTTTATTCTCTTCATTTAATGATGAAAGATTATCTTCCATTACGGATATTTCTTCTTCTATTTCTCTTATTTTATATTCTACTTTTCCTTTCTTCTTAATTTTTTCTCCTAGTTCTATCTCTAATCTTTCTATTTGTCTTATTAGTTCTCTCTCCGCATAGCTTGTTCCATTACTAGAAGTTTGTACTATTTCATCATATGTTCTACTTCTAGATTCTTCTTCTAATGTCACGTTATTATTTTTAATTTTATCCATTATAATTTCTATTCTATTAGAAAGATGCTTGACTCTATTCTTTAGTTTATTCAATTCTTTTTTACTTCTAAAATGCCTATATAATCTTTCTTCTGTTTTTATATATAATTTTTTATCCAACATATCTAACCTCCTATAATAATTCTTTAATATATTTTCTTATAACTATAACGCTATTTTTTGATATCTTTAAAGACCTTTAGAAATGCCTTTTGGTTTGAAATTTATATGCTTTTTTACATTTCTTTATTATTTTTATTTAACTCATATATCATTATTTCTTTTCCCACAATATCTAAAGCTTTTTGTAAATCTTTTATTGTAAAGTAATGCTTGACCACTTCATCCGTCCAGCTATTTTTCGCGACTCTTAAAAATTCTAATTCCTCTTGATATTTGTCTAATAAATTTATACTTTCCTTTAATAATTTCTCATACTCTATGCTTTTCTTTACATACTCTTTTAATAAAATCTTTAATACTGCATTTTCTTCTCTAAATGACCCTATCTCTTCAAAAACTTTATTTTCTATTTCTTTAACTAATATAGTTGACATCTTATACCTCCATCATACTTAATTTTCTATTATATTATTCAAGACAATCAATATTCTTATTTCAATAATTCTTTTAATATTTCTGTTTTCTCTTTAGCTTTTTCTTCTCTTATATTTTTACCATCATTTAAAATAGGAGTGCACATTTCTAAAATTCTATAGTATGTCCTCTTTTCATATCTATTTTTAAGTTCTATAAGAGATAAATTTGTTGTAATTATAAGTGGTAATCCATTCCTATATCTACTATCTAAAATATTATAGATTTTAGTTCTAGTCCACTCTGTATCCTGTTCTGTTCCCAAATCATCTATTATTAATAGATCTGCATTATCTAATCCTCTTAATACATCTTCTTCCACTTCTTTTCCAGATTTTTTATATGTGTCTTTAATTCTATTCAATAAGCTGTCTGCATTTACACATATAACTGGTAACATTTTCCCTATAAGAAAGTTTGCTATACATGCCACAGTATAGGTTTTACCATTTCCTGGAGAGCCATATAATAAAAGCCCTACAGATTCTTTTTTCATGTTTTCAAATTTTTTAGTATATTTATTAGCTATTTTATACATTTTGTCATTGCCTTTAGTAAAATCCCAATTTTTAAATTTACTATTTCTAAATTTTTCATCTATTAAACTATTTTTAATAATCTTTTTTAATCTTAATTGCTTTTCTTTATTTATTTTTTCTTTCTCTTTTGCCATTAGAGCTTCTCTTTTGCACTTGCACATTACAGGACCTTTTATACACCTATTTAACCCTGGAATATAAGTAATCTTTTCAATAGCTTCTCCACATACAGAACATATTTCAACTCTTTCATTTTCACCAGCAATATTATAATCCAATTCCCTGCTTTTTAAGGTCTTCTCCAAAGCTTCTCCTACTTGTTTCATATACCTCGCCTTCTCTCCATTTCTTACTTATCTCGTTTTTCTTTACATCTTGTGGTAATTTATATCCTTTATTTATCCAGCTTTCCAAGATTGACATTGTATATTTAAATCCTTTTATTTTGCCCTGTTCCTGTTCTCTTTTTTTTGTAATATCTAATGCATATATTAATAAATCAGTATAATCTTCTTTAGCCATGACTTTTAATACTTGATTTAAATAAGTAGCACTTATTTGCCTATAAAAAGTATTAAAATATGCTTCATTAATTTTATCTAAATTTTTTCTTATATCACTCTTTCTATCTTCTTTTATTTCTATATCTATATCTTCTATATCTATATCTCTGCCGTTACTTAACGTTTCATGTAACATTATATTTTTTTTATTGTCATTATTTTTGCAACTTTGTCTTTTAGTTTCTTCCAATAGTTCTTTTTTCTTAGCTCTATGTTTAGCTACCCTTTCCCTTGTTTGTTGTCTAACTTTCTCCATACCTTCTATATTTTGATGTTTGGACCAGTTAGCTATTTTTATTAATTTATCATCTTGTATCTGTATCATGCCAAAATCTCTAAGTACTTTTAATGCAAACCTTAAACTATTTAATGGCCTATTAAAAATTGTACTTAGCATTTCTTCTGTATATGGAACATTATCATTTAGAAAAATATATCCATTTGCATTTGTTTTACCTGCTTGAACTAAAAGTCTCATCCAAATATAATGAACAGTATCTCTTTCTGGCATGGCATCTATTAATTTTATTTTTTCATCATCAAACATATTAGTTGTTATCTTTATCCATTTAACTTCTGCCAACATATCACCGCTTTCTTTTTTATCCATATTACACGAAATAAAATATTGCTATAATTAAATCAATATATAATCTATATATAGCTTTTTTATACTTCTTTAATAATTATTAATTTACTATGTTTACCACCACCTCCATAGTTCTTGATCTATCAATTCATTAGGTGTAATTTTCAATGTTTTGCATAGATTACAAATAACCTTTAACCCTGGATTTTCATATTTACCTTCCTCTAATTCTGTAATATAACTTCTAGCTATTTTACTTTTGTAACTCAATTTTGAAATAGATAAGTTTCTTATTCTTCTATATTCTTTTGTTTTTATTACTGCCACTTGAGGATTCCTCCTTAGGATTTATTCCTCTCAATATTAAACTATAAATTTTTAAGTATTCCTAAAGTTTACTATTTCTTCTAAAAAAAAGTTCGTCTATAGTAGTATCAAAAAAATCTGATATAATCTTAGCCTCATTTAAGGTAAAAGATTTCTTACCATTTTCTTTAAAATTATACGTATTTAGAGACACTCCTATTAGTCTTGCTATATCCTCTTGCTTTGCACCTTTTAGGCATCTATAAGCTTTTAATTTTTTTGCTGTTGTCATAAAACCCACCCCCTTAATAGCTTTTTTAAGTAAACTATAAGAATACTATTTATATTTTTATTATAGTCAACATTAAGAATACTTTCAACTGCATTTTATGATTTTTTTCAAAAAATATTCTTATAGTTTACATCAGTTTTAAAAAGTCAACATATGGTTTATAATATAGTATAAATAGAGGGGTGAAAAAGTTGGCAGAAATAAAAGATAGGTTAAAATGTGAAAGATTAAGAAAAGATTTAAATCAAACTGAATTGGCAAAATTTTTAAATGTATCAAAGCAAACAGTTTCCAATTGGGAAAATGGTAACAGAATTCCTGATACCCTTACCTTATCTAAGTTAGCTGACTTCTTTAATTGCTCCGTAGATTATATTTTAGGAAGATCTGAAAATAGAAATGGCATAATTTCTAAAGCTAATATAGATGGAAGTAATTACGAATTTGAATTAGATAAGAGTATATTTCCAAATGGCATAACTAGAGAACAAATGATAAATTATATTAAGGAATTAGAAGAAAGAAATAAAGAATTAGAAAAAGAAGCTGAGATATCTAGAAAATTAAAAGAAGCTGGCTTCGATTTCAATCCCGATAAATAAAATATTCTAAAAATTAATTATTTAAAATTAAAATATAAGTATGGAAAACTAACAAATATATATGTATTCATGATGTTATGTTTATAATTACATGAAATTCGTATATGTTTGTTAGTTTTTTATTTTGTCTAAAAAAGTAAATACTTGTCCTAAAATTCTGTATACAGACAATTACATTTTCAAAATAAATATGTAATAATTTTCACATAAAGTAATTTAATTATATAAACTTGCAAATTTTATTGAAAGATATTAAAATATAGTTGAACACATGTTCGATTTGAGAAAGGAGTCTTAATTTATGTTTAATTTTAGTGGGGTATTAAGTATAAAAAAAGAAGGGGAAATAATATATGAAAAAAAAGATACCTTTACACTGAATAGAAAAAAAACTTCTTGTGAAAAATCTTCTAAGGATAAAATACAATTAGTGCAGAAGGTTAATACATAATATAAAGAATATATAATAACTTCAAAATATAGTTGAAAGAAAAGTGTTAAGAAAGATGAGACTAAAGAACTACTTTAGAACAGTATATACACAACTTAATCGTTACAACTTATAAATTAAATAAGATAAAAAAACAAGTGCTGCTCCTTAGAAAATAAAATTACAACAACTTGATCTTTTTCATTTTAAAAATTTTTATAATTTATAGTTAAATCATTGAATTCTAAAACTGTATTACAATATCATAGAGTAATAATACATAAAATATTAAATAAAAATCATAGACTAAAATATATCTAACCTAATAGAATTATATAAAATAAAACTGGAACATTAAATATTAAAGAAGCTATTCAAACCTTAACACTTTTTAATAACTTTAGAGTATAAATGCTAATTTAGAAAATGCTTTGCTATTAAGCACTAAGGAAATTCTAAATCCAGAATATTTAAAGAATTAATGAATGTTATTTATTTTTAATTCTTCTACTAACTTTCTAATGATATTTTAAAATAAAAAAGACTTTGGAAAATTAATCCAAAGTCTTCAATGTTATATCTATAATGGTGCCGAAGGCGGGAGTCGAACCCGCACGAAGTTACCCTCGACGGATTTTGAATCCGTTGCGTCTGCCAATTCCACCACTCCGGCAAGAATGATTTAACGTTATTATAATAACATATTAAAGGCTTTTAGTCAACCAACATTTTCATTTTTTATGCTACATTGAAAGACTGGTAATCTTAAAAACAGCTAAATCTTAAAATAATTATACTTCCCTTCTAAAAATCAAATAATTTATTCCTCGCAAATAAAATTTATAGTTTTATATTAAACATTAATAGATTATTATAAAAATTTATAAAAAGTTAACCATATCTTATCAGGCTATTCATTGAGTCTTTACATATAAGGCTTATAATAATTCTTGTAAATTTTTGTCGAAAAATATGAAAATATTAGTAAACTAAAAATTAAAAAAGGAGGAGAACGTCTATAAAAATTGTTTCTAAAAAGTTCATGCAATCTAGTATTTATCATATTGGGATTATGAATTAATTAAGAAGGAGTGTATGATAATTGTTATTTAACTCAATGCATTTTTTATTGTTTTTTCCAATCGTTACTTTTATATATTTTTTTATCCCCCATAAATTTCGTTATATCTGGTTACTTATAACTAGTTATTATTTTTATATGAGTTGGAATCCTAAATATGCATTATTAATTGGTATTTCAACAATAATTACATATTTAAGTGGTATATTAATAGAAAAATCAAATAAAATAACTGATAAACAAAAATCAAAATTTTTTAAAAAACTTTGGGTTTTCTTAAGTTTATTTATTAATTTAAGCATATTGTTCTTATTTAAATATTGTAATTTTTTCACATATACCCTTACAAAAATATTTTCCTTAATTAATATTACAATTAAAGTACCCTCCTTTGACTTTATATTACCTGTAGGAATCTCTTTCTACACATTCCAGGCTCTTAGCTATACTATAGATGTCTACAGAGGTAATATTAAATTTGAAAAAAATCTAGGCAAATATGCTTTGTTTGTGTCATTTTTTCCTCAATTAGTGGCTGGACCTATAGAAAAATCAAAAGATTTATTGAATCAATTTAATGAAAAACATATATTTGATTATAATAGAGTAAAAAATGGTTTAGTACTAATGCTATGGGGATTTTTCCAAAAGGTATTCGTTTCTGATAGATTAGCTATTCTAGTAGATACTGTATTTAATAACCCTAGTAATTATAAAGGTTTAGAAATTATTGTTGCATCTGTTTTTTTTGCCATTCAAATCTATTGCGACTTTTCTTCTTATTCAAATATAGCTAGAGGAGCTGCTGAAGTTATGGGATTTGATTTATCACTAAACTTTAAACAACCTTATTTTTCAAAATCAATACAAGAATTTTGGAGACGTTGGCATATTACTCTCGGAGCTTGGTTTAAGGATTACTTATATATACCTTTAGGTGGAAATAAGTGCAGCAAATGGAGAAGATATTTTAATAATATGATTGTATTCTTAATAAGTGGATTATGGCATGGAGCAGCTATAAATTTTATAATCTGGGGTGGCCTACATGGATTTTACATAATAATAGGAGATATGCTAAAGCCACTTAAAGAAAAAATAATAAATAATTTAAAGATAAAAACTAATGTATTTAGCTTTAAATTATTCCAAACATTGTTTACTTTCATATTAGTTGATTTTTCATGGATATTTTTTAGAGCAAATTCCTTTTCCGAATCTAAACTATTAATTAAAAATATGTTTTACTTTAATCCATGGATATTTACCTCTGGTTCCATCTATAAATTAGGATTAGATCAAAATGATTTTAAAATGTCAATACTAGGCATATTAATAGTTTTTATTATAGATAGTATTGCAAGAAATAAAGATGTACGTGTTGAACTCTCTAATCAAAATATAGTATTTAGATGCGCTATTTATTTATCTGCTATTTTCTTTGTATTAATATTGGGTATATATGGAGCAGGGTATGATGCCAATCAATTTATTTATTTTCAGTTTTAA

Protein sequences of DBSCAN-SWA_5

>NC_017297|3253962:3275563|3267868_3268153_-|WP_012100779.1|DBSCAN-SWA
MRTPLEILKFNLQEKQYPYFEDKELELLLEINNNDVEKSSYKGCILKAIADDGIEVADIKLQSNRAYWLTLAEHFKEEQKILKNQTSMERVDEH
>NC_017297|3253962:3275563|3269668_3270517_-|WP_046665300.1|DBSCAN-SWA
MKQVGEALEKTLKSRELDYNIAGENERVEICSVCGEAIEKITYIPGLNRCIKGPVMCKCKREALMAKEKEKINKEKQLRLKKIIKNSLIDEKFRNSKFKNWDFTKGNDKMYKIANKYTKKFENMKKESVGLLLYGSPGNGKTYTVACIANFLIGKMLPVICVNADSLLNRIKDTYKKSGKEVEEDVLRGLDNADLLIIDDLGTEQDTEWTRTKIYNILDSRYRNGLPLIITTNLSLIELKNRYEKRTYYRILEMCTPILNDGKNIREEKAKEKTEILKELLK
>NC_017297|3253962:3275563|3271731_3271941_-|WP_012100783.1|DBSCAN-SWA
MTTAKKLKAYRCLKGAKQEDIARLIGVSLNTYNFKENGKKSFTLNEAKIISDFFDTTIDELFFRRNSKL
>NC_017297|3253962:3275563|3265403_3265820_-|WP_012100775.1|DBSCAN-SWA
MDLKVTNIEDLKNVAQGEVIQLPQFGQGIPFNARVKRVSLLNLVRKGVVPNKLLSAAEELFYGKQSSKENIDLAQMTDVMYIMAENALVEPSIEDLKSVGLELTDEQIIALFNYTQEGVSELDSFREESENTECNINK
>NC_017297|3253962:3275563|3259515_3260484_-|WP_012100768.1|DBSCAN-SWA
MSLPKYIINFEELTEDLKNHLLSLIDDNIRTNYPEINTNNIQDLLQQLKDLLPSVQYEGLKKKIDTFIYRKIEGIQKVKGILLDIPAIQNNYTEQFKFDKDVYITGLHFNQTGWKKEDRFSLEVNKIKIIDNATTKEIGEHKYFNTFYKVNANTLISFIFHNLSGNSRQTMVDLEYIDGEDSSITPGIEDIDNEWDIAVVMNWEENTDADIDLHGEIDGKKVWYGNKSYDGFYLNFDYTSHKTNKNPEIISVKGYKNKKLLISIKNFNGVELKEPVTLEIYQYRSYGNKLLKKFNVNLDTNRDLKDIFIMDLNTLKITNLNK
>NC_017297|3253962:3275563|3256069_3256324_-|WP_003360052.1|DBSCAN-SWA
MLTSTIDFKKTRQKMWGILKNKTLAQLPYGHETDKNGSEITSYATNCYEDALEEAHTLLANGIGTKDIQIVEFVPYDYIMQPRV
>NC_017297|3253962:3275563|3256329_3258225_-|WP_012100766.1|DBSCAN-SWA
MPLHKIPLCSFKYVGDTTFSSGTFIYDTTEKVAKTTEKLFYKETMSEIDKIKGDKLFYKEPKDNIEKEKNKYISKEITDIKKEFEKELKLRNKEINKNNAISLDKIKDIGINRKTSKELDIRKNTDISICYNNKLLKREMLQLNKANNLINLSIDRENLQLNKFKSIYTDSIVEKEIFKGESLQNLKLEKYINIEKNIGYYLYRIYCKEIDIDKSKFVQKHGFKNINKNNYRFIDKCNLKEAAKMSNKTMLNKDIIIGIDIDTSINNLKILDLKDIDRNYKTMLMYNIALKDIEKYRIKNTLNKIEHKEICKDHNKKYFYKDVFKFIDKSINRYLDRQAIRSIFKYNNRYLDREYTTNIFKHKEKYLDNSPIINIYKQIERDLLNLSIWQIYRQSNKYLNNEAIRQIYTPNKNKFIEITKRWWWLKPTNPTDRLIVPNKDYIYNNDLLNNLDYEYLRFSNHPIEWGKDWGVDYNIPPMTISTEIMLDLINILAMIWHKNAQAWLSCTGKESIQFIMELIYDWYTLDTSSPNADYIRAYRWIRWEAEKVYFLNTENGLQAIGLLIANLIDYLKQHHFNLVPIWHNPKAMDIERKFNKVATNGDIMKDLDKLKGKRNYMIETQNFEKKNIFGR
>NC_017297|3253962:3275563|3270458_3271364_-|WP_012100782.1|DBSCAN-SWA
MDKKESGDMLAEVKWIKITTNMFDDEKIKLIDAMPERDTVHYIWMRLLVQAGKTNANGYIFLNDNVPYTEEMLSTIFNRPLNSLRFALKVLRDFGMIQIQDDKLIKIANWSKHQNIEGMEKVRQQTRERVAKHRAKKKELLEETKRQSCKNNDNKKNIMLHETLSNGRDIDIEDIDIEIKEDRKSDIRKNLDKINEAYFNTFYRQISATYLNQVLKVMAKEDYTDLLIYALDITKKREQEQGKIKGFKYTMSILESWINKGYKLPQDVKKNEISKKWREGEVYETSRRSFGEDLKKQGIGL
>NC_017297|3253962:3275563|3258239_3259493_-|WP_012100767.1|DBSCAN-SWA
MATDNFYFIEGNSSVKDLVKTLVTEITQNSGIYKWDLVYPDSIDKIGSTGEGSTINLITDNSKTDKVETVFRIGSQNDKCIIKATTTYGKEFYLKIDRKEEDLTKEEKEAIVNFNKLHSYYIGDGHYSNRTDAETLEYMAGLPTKGASSGTGNNELYTTYVSAMTKSNSINNIRLQISDKLNGDGTDLGISKSIQSEYNYRLAWYRKLQPEIKDFLPVQYWINVTKDSINLVLRGDPSADVHPYENYLTSYAYIGALKPVEDSAYTDDKYNFGITVSSDIEPNYSKVYGERTATGVTDVCMIANKIGMPYQPHYPAFYATNPFMDKCNVEGSRYNHKKHQFSDITLVHPVDMERGKMINVLVGDASAINDTDRLAYKKDTEEEEYYKKFKITAPYCFLNNSANINYCIAIRCYKTTK
>NC_017297|3253962:3275563|3253962_3255048_-|WP_012100764.1|DBSCAN-SWA
MSEFFNVTLDKDIILDDSVISNKTGWSSEKIQKEIINKRITKFEELEDVDVTNKKNKQLVAYSEETGKFTTIDGIDAGEIVGAGMKQISKMGIVGSAETPRIVNIPVNTVDFKVPRVNVLRYDTENTQDLISVKNEFTNDESNDFIDDKMMTFDGKAHLETNHISDFEVVQDTESFIEYSVNVDKTLFKKIGGFETFEDGVIQKLKTKAIPFDRLLIPKGDMNLSNVDHIDYFRLTANGNNIRIVCSVDSGNTWKTFSGEKWVNVNLTVDDVRKNGMNIATFNAINDVFWNELVTTKKIRFAYLFSMDSITDIEEIDKLDLQYDGVGRWKQVKEDLYEVIYASNTLLQVECKFSGDIKINY
>NC_017297|3253962:3275563|3271457_3271691_-|WP_072570747.1|DBSCAN-SWA
MLRRNPQVAVIKTKEYRRIRNLSISKLSYKSKIARSYITELEEGKYENPGLKVICNLCKTLKITPNELIDQELWRWW
>NC_017297|3253962:3275563|3272844_3272994_+|WP_003403583.1|DBSCAN-SWA
MFNFSGVLSIKKEGEIIYEKKDTFTLNRKKTSCEKSSKDKIQLVQKVNT
>NC_017297|3253962:3275563|3262203_3263289_-|WP_012100771.1|DBSCAN-SWA
MTKCKVEFYKKNGYQAFENGDANKITLEHCLVSVKINRNLTTPTAEATITAQYENLPTAIFAGGIQGIIDNFAQVKIYIEDVLQFTGVIKKYDYNTLDKTIEMTCHDMYYRMLNLCDKELKFYNKTAADIISTVVSDAKCSFQRSGGNNYTVPKLECEIGTMYNDIISNLVETMYARIRANKNGAIILEEQYPAYNESNHEANHHDYVLSVDTNLSSETASRDSNLMRNILKICCNDKYSIFESKAMTSYLNGERWVDIIDNPLASTPLLKQKVAGYKFLDMWRESTALNVVPVAGIPNIDLGQVVKLINNQRGNGWYLIVGISTEINADTYVDTLQLQGMRDKTKVYDQCIQIGSGRLKQ
>NC_017297|3253962:3275563|3274075_3275563_+|WP_012100784.1|DBSCAN-SWA
MLFNSMHFLLFFPIVTFIYFFIPHKFRYIWLLITSYYFYMSWNPKYALLIGISTIITYLSGILIEKSNKITDKQKSKFFKKLWVFLSLFINLSILFLFKYCNFFTYTLTKIFSLINITIKVPSFDFILPVGISFYTFQALSYTIDVYRGNIKFEKNLGKYALFVSFFPQLVAGPIEKSKDLLNQFNEKHIFDYNRVKNGLVLMLWGFFQKVFVSDRLAILVDTVFNNPSNYKGLEIIVASVFFAIQIYCDFSSYSNIARGAAEVMGFDLSLNFKQPYFSKSIQEFWRRWHITLGAWFKDYLYIPLGGNKCSKWRRYFNNMIVFLISGLWHGAAINFIIWGGLHGFYIIIGDMLKPLKEKIINNLKIKTNVFSFKLFQTLFTFILVDFSWIFFRANSFSESKLLIKNMFYFNPWIFTSGSIYKLGLDQNDFKMSILGILIVFIIDSIARNKDVRVELSNQNIVFRCAIYLSAIFFVLILGIYGAGYDANQFIYFQF
>NC_017297|3253962:3275563|3255059_3256058_-|WP_012100765.1|DBSCAN-SWA
MKLIQVKNGLLEAENFFLASSFADFAGESNVTRDIKAGKLKLISNNKMERKFDYKEFVLEVEKENFNDIKDMDYSMIYLGNSNHIFGIKDLKSNEQNRYWKILKKDNYIQAYSSNDGKSYINIGGMEFIEPLTKQGFMKYSDEDFILNNYKVYANPYVTIENFPENTLCELYDLDNNLIKTRLFNSDMECKVFIDGNMMAYFTFKDTDGKVIYTSDVLQLQYGDMWVFSPYNFEIIYHGNVVTNVSPAMLQDLEELITIKNIGNKDYNNIKIGTKTPSNDLIQLSFDGINYTDSLTINSIKQCESKGIYVKITKNAENHNFAIRDFHLVVSE
>NC_017297|3253962:3275563|3265834_3266722_-|WP_012100776.1|DBSCAN-SWA
MTSGKTLVNVVKVNFIDEVTNTKHTIETSNEIDIEPINSKGKRDILRIKNKIYGINETDDIVIGYKLKMKDNLFNIETMALIDGGTIQDNKYCGTEVGIAVERHPFTMEIFTEEKDYSRTTGYVKFVYKHCKGKPAKYKIQDGKFLVSSYEAESIPFRNEKPVEIEFINKLEENDNGEKPGETTPIEDIGVEGGKVENNNPDVGVSITNRVVWSFSNQINQDDVNLENFIIKRKSDDSRVNGNVTIDDTKKIVTFVPDSLSIDTVYIAEAKEINKLDGSGKTTALSTEFKTIKIR
>NC_017297|3253962:3275563|3260485_3261835_-|WP_012100769.1|DBSCAN-SWA
MELPSYVVNFDELSDLIKDYLQNGVKVDIGNINFSTKDMENLLSEIKDKIQGVDYNDLINALNALGVKLDNLSGNLGISGTQKIYGKMLEIPAVKGQHIIEFKGNGQITGITYSQSSWRFEDSWDLQVGNDKLFESVRTKEYGEHKFLNVFYPINGTVKFIYNNISGTSKVLWVDFNILENSNLPTPTTPTIPTTSEKNYRFLAIGESEYTLQGANNLMGCTYDADNMSNLFKEHKQSAKFTKNIVAKNKTKSEALNLIKNTFQDAQDNDISYLFWSGHGTVYEDKFALVAKDNIITVYELQTILDDIKGTKVIFIDTCHSGLAIDKNFAYTLAVVEEKLRSIDKTLNKQGYKVLTASAGSETSGDLSAGYNGNPNPSGAFTWALTQSIKTKKSDKDKNRIVTLEELYQSVLHFYDEFNIKNPYLKITQTAQVYPRNDTSSIFEYKEGA
>NC_017297|3253962:3275563|3269291_3269612_-|WP_003483819.1|DBSCAN-SWA
MSTILVKEIENKVFEEIGSFREENAVLKILLKEYVKKSIEYEKLLKESINLLDKYQEELEFLRVAKNSWTDEVVKHYFTIKDLQKALDIVGKEIMIYELNKNNKEM
>NC_017297|3253962:3275563|3263722_3265126_-|WP_012100773.1|DBSCAN-SWA
MAVNVGEAVAHLTLDTSEFKKALNGAGKDLEIFVHKVEEEKTKIEKLQEALAKKAGTFSKIGKSMEKPSAVAQNLLKTGMKNTLAEEAKSKNPKKGPANIAKSNYEKIQKDIQASIKKVQDSFAQLQASIVKQLIPIFNNQLVPILNNKLIPIFTKLANKAVELMNSFNKLPNPVKNAIAIIIVSIAGVAKTFTVLSKLVGTINNVIGIFGKLKKAGGIFGLLKTIITSKTLLILVAIAAIGLIVYEVIKHWDQLKKAADDLGKKISNVCKKISGHFDKNIKKWKIKWKAFRTYMHKIGQDIMRGLVSGLKEGIKKVRETIESIANEIKNRFKKMLGINSPSRVFADYGNFIGEGLIQGIDNQESAINNKFKGIANKIKGLGNVRPNFNGLNNMSLSGAYGGTYASPYGPNNMNKSMGLTQDIKMYVTIPNADKEGANKIANEFKQMTESSMKNVMTGLFMNDVLRD
>NC_017297|3253962:3275563|3266726_3267146_-|WP_003403551.1|DBSCAN-SWA
MSKFNYKVPGDCIQQDIIDNAVPETLWQKVYLCLKKLGYNVYAPGQKRNKCTESYVVIKENGVHALVGNISGYKLFDIIVYNPMDQYSTMEFYVENLKEALKKIQDLRPTGNETPSIIDYDVQAYTTSIEYQQFKSLRR
>NC_017297|3253962:3275563|3272132_3272543_+|WP_003360073.1|DBSCAN-SWA
MAEIKDRLKCERLRKDLNQTELAKFLNVSKQTVSNWENGNRIPDTLTLSKLADFFNCSVDYILGRSENRNGIISKANIDGSNYEFELDKSIFPNGITREQMINYIKELEERNKELEKEAEISRKLKEAGFDFNPDK
>NC_017297|3253962:3275563|3261849_3262191_-|WP_012100770.1|DBSCAN-SWA
MAHMGYKNFRKPVVYILDQELRKRNFKNQINTNEDSKYTGELPEYPCRIIRDSNNKAYKFIYASGTDMQWQEELIRNAEGKVYRIKTTYPNNTNKTIQLIKDNHGKLETIDYV
>NC_017297|3253962:3275563|3263275_3263710_-|WP_012100772.1|DBSCAN-SWA
MDLNRIKDFKVDLLYQDGKNTGGVITNYKPPRPAYFRKGIRTVQGYTYFEKNIKSDCIIEFTVAFNIKGENDEKTQSNITKFLNFRKNYSGRFIFIDEFGIQYKGYLQNKFEIDTPIEGDIYYINLELLCNHEASGWVKDNDKV
>NC_017297|3253962:3275563|3265201_3265369_-|WP_012100774.1|DBSCAN-SWA
MTNDYEAFCFDEACVYILNEISKEDAREPKFIDGDRTNKTNNEDVIQWLNANNRK
>NC_017297|3253962:3275563|3267503_3267869_-|WP_012100778.1|DBSCAN-SWA
MNNINRAKISKNIYEHLEKKDLLREIKILRIGKNAFEEKLDEVYVCTIKGYYYRNNSNIITTSMEGLEFNNLYNDKLLIIYNDISSKIQKDDYFILDGTKYEIVDTGNIQNLVFDMILNRV
>NC_017297|3253962:3275563|3268656_3269178_-|WP_012100780.1|DBSCAN-SWA
MLDKKLYIKTEERLYRHFRSKKELNKLKNRVKHLSNRIEIIMDKIKNNNVTLEEESRSRTYDEIVQTSSNGTSYAERELIRQIERLEIELGEKIKKKGKVEYKIREIEEEISVMEDNLSSLNEENKKFIELKYGENKSVDWIAVEMFGRARSTAYRKKNELVEHVAQLNNLIV
>NC_017297|3253962:3275563|3267151_3267499_-|WP_012100777.1|DBSCAN-SWA
MSEFEVNIDSVIDGLSEFEMQSKTAISGYADIAAKKLEEDAKKNAPWKEQSGKDIETIKGGEQWKGDKCNIYISGNKDYYSSLELCNDKKYAILKPTIDKLSPQILKGMSNLFGK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012100764.1|3253962_3255048_-	hypothetical protein	A0A0A7RU66	Clostridium_phage	1.5e-140	69.8
WP_012100765.1|3255059_3256058_-	hypothetical protein	A0A0A7RW91	Clostridium_phage	7.5e-139	71.4
WP_003360052.1|3256069_3256324_-	hypothetical protein	A0A0A7S0T0	Clostridium_phage	1.1e-33	81.0
WP_012100766.1|3256329_3258225_-	hypothetical protein	A0A0A7RU09	Clostridium_phage	4.6e-113	51.5
WP_012100767.1|3258239_3259493_-	hypothetical protein	A0A0A7RU28	Clostridium_phage	1.1e-192	78.9
WP_012100768.1|3259515_3260484_-	hypothetical protein	A0A0A7RU61	Clostridium_phage	3.0e-108	60.5
WP_012100769.1|3260485_3261835_-	caspase family protein	A0A0A7RW86	Clostridium_phage	2.3e-74	74.1
WP_012100770.1|3261849_3262191_-	hypothetical protein	A0A0A7S0S4	Clostridium_phage	7.2e-17	57.1
WP_012100771.1|3262203_3263289_-	hypothetical protein	NA	NA	NA	NA
WP_012100772.1|3263275_3263710_-	hypothetical protein	NA	NA	NA	NA
WP_012100773.1|3263722_3265126_-	membrane protein	A0A0A7RU22	Clostridium_phage	7.8e-33	42.0
WP_012100774.1|3265201_3265369_-	hypothetical protein	A0A0A7RW80	Clostridium_phage	4.3e-15	68.5
WP_012100775.1|3265403_3265820_-	hypothetical protein	A0A0A7S0S0	Clostridium_phage	1.7e-44	68.2
WP_012100776.1|3265834_3266722_-	hypothetical protein	A0A0A7RTZ9	Clostridium_phage	2.6e-119	74.7
WP_003403551.1|3266726_3267146_-	hypothetical protein	A0A0A7RU17	Clostridium_phage	6.0e-58	72.7
WP_012100777.1|3267151_3267499_-	hypothetical protein	A0A0A7RU51	Clostridium_phage	4.7e-32	58.0
WP_012100778.1|3267503_3267869_-	hypothetical protein	A0A0A7RW73	Clostridium_phage	2.2e-32	57.0
WP_012100779.1|3267868_3268153_-	hypothetical protein	A0A0A7S0R4	Clostridium_phage	2.3e-24	59.2
WP_012100780.1|3268656_3269178_-	hypothetical protein	A0A0A7RVS1	Clostridium_phage	1.4e-35	50.0
WP_003483819.1|3269291_3269612_-	hypothetical protein	NA	NA	NA	NA
WP_046665300.1|3269668_3270517_-	ATP-binding protein	A0A2K9V3L7	Faecalibacterium_phage	4.0e-32	34.8
WP_012100782.1|3270458_3271364_-	hypothetical protein	A8ASN4	Listeria_phage	9.4e-40	38.7
WP_072570747.1|3271457_3271691_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012100783.1|3271731_3271941_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003360073.1|3272132_3272543_+	helix-turn-helix domain-containing protein	A0A0A7RUJ5	Clostridium_phage	1.0e-09	56.2
WP_003403583.1|3272844_3272994_+	hypothetical protein	NA	NA	NA	NA
WP_012100784.1|3274075_3275563_+	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	6.2e-65	37.8

Sequences of DBSCAN-SWA_6

Nucleotide sequences of DBSCAN-SWA_6

>NC_017297|3378914:3462532|DBSCAN-SWA
TTTAGTTAGTTTTGTTCTTAATTTCATTCTTTATTTTTTCTATAAATTCTTCTAAGGATATAGCCCCTAAATCTCCATCTTTTCTACTTCTTACAGCAACTTTTCCTGCTTCCACTTCTTTATCTCCAAGTATTAGCATATATGGCACTTTTTGAAGCTGAGCTTCTCTTATCTTATACCCTATTTTTTCATTTCTTGTATCAATTTCTACCCTTATATTATTTTCTTTAAGAGTTTCTTCAACTTTCTTTAAATAATCATATTGAGAATCAGTTATATTCATTAATTTAACTTGTACTGGAGCAAGCCATGTTGGGAATGCACCTGCATATTGTTCTATTAATATACCTATAAATCTTTCAACACTTCCATATATAGTTCTATGAACCATAACAGGTCTATGCTTTTCACCATCTGCACCTATATATGATAAATCGAATCTTTCTGGCATTTGGAAGTCAAGTTGAATAGTTCCGCATTGCCATGTTCTGCCTATACAATCCTTTAAATGGAAATCTATCTTTGGACCATAGAAAGCTCCGTCACCTTCATTTACTCTATATTCTTTTCCTATAGAATCTAAAGCTTCTCTTAAACCATTAGTTGCTATTTCCCAATCTTCATCACTTCCCATAGAATCTTCTGGTCTTGTTGAAAGCTCTACAAAATATTCAAATCCAAATAGTTTATAGAATTCATCTATTAATTTAATTATTCCTATTACTTCTTCTTTTATCTGTTCTTTTGTCATATATAAATGGGCATCATCTTGAGTAAAACATCTTACTCTCATAAGTCCATGTAATGCTCCTGATAATTCATGTCTATGAACTATTCCTAATTCTGAAAGTCTTAATGGAAGATCTCTATAAGAATGCATAGAACTTTTATAAACTAGTATTCCTCCTGGACAATTCATAGGTTTTATTGCATAATCACCATCATCTATATTAGTAAAATACATATTCTCTTTGTAGTGATCCCAGTGACCTGATTGATGCCATAAAGCTTCATTTAATATTAATGGTGTCCTTATTTCTTGATATCCTGCTTTTGTATGCTTTTCTCTCCAAAAACTTTCAAGAATGTTTCTTACAATCATTCCCTTTGGATGAAAGAATGGAAATCCTGGTCCCTCTTCATGTATGCTAAATAAATCTAATTCTTTACCTAATTTTCTATGATCTCTTTTTTTAGCTTCTTCAATCATATTTAAATATTCGTCTAGCTCACTTTTTTTAGTAAAGGCTGTACCATATATCCTTTGAAGCATTTTATTTTTTTCATCGCCTCTCCAATAAGCTCCAGCTAGAGATAACAATTTTACTGATTTAACCTTTCCTGTAGATGGTACATGAGGTCCTGCACATAAATCTGTAAAGTCTCCTTGTTTATAAAAAGATATAACTTCTCCTTCTGGTAAATCTTCTATAAGCTCAACCTTATAATCCTCATTCTTTTCTTTCATAAGATTTATTGCTTCTTCTCTTGGTAATTCAAATCTTTCTAACTTATGATTTTCCTTTATTATTTTTTTAATTTCTGCTTCTATTTTTTCTAACATTTCTGGTGTAAAAGTAAAATCTGCTTCAAAATCATAATAAAAACCAGTGTCTATAGCAGGTCCTATAGCTAATTTTACTTCTGGGTATAATCTTTTAACTGCTTGTGCTAATATATGTGCACCAGTATGTCTTAAAGCCCATTTACCCATTTCATCTTCAAATGTTAAAATTTCTAGACTACTATCTTTGTGTAATTCAGTCATTAAGTCCACAGTTTCTCCATCTATTTTAGCTGCTAAAGCTTTTTTATAAAGAGCTGGACTAATTTTCATAGCAATATCAGATATTTTTATTCCTTCTTCAATTTCCATTACTTTGCCATCTTTTAATGTGATTTTTATCATAAAATTGTCCTCCTTCAAATAAAAATTTACAAATAAAAAAACTCATCCCAACACATGGGACGAGTGTATTTTCGTGGTTCCACCCAATTTAATAGCAGTGCACTACTATTATCTCTTTATCCTTTAACGCAGGAAACGGTCATACTTACTTAATTCAGTATACAACTCTAAGGTGGTTTTCAATAGAACTTATTCAGAAAATCTTTCAGCCTATGGATCTTCTTCTCTTTGAATAGTAATCTATTTACTCTTCCTTTTCATAGTTTATAAATCTATTTTTAATTTAGATATATTATATTAGCTATAGAGATAAATGTCAATACCATAATACTCTTTTATAGAATTTATTAAAGTTTATTATAAGTATGCTTTAATTTGATAGGTTTATCATGATTATAGATATTAACTCTCTCTTCAAAAACATTCTTTATAGTATTAATTAATTCCTTATTCGTACAATTTTCAATATTATATATATTAATTTCTTTAGGTACATTAGTTATAAGCCAACTTATAAGCATATCATCTACAGATATATTTTCTACATATTTAACATCGGAAACTTCTATATAAACTTCTTCTGTTAAGTCATTTCCCTCAGAATCTTTTAAAGTATATTTTCCAGTAGGATCTATTAATATATTTAGTTTATCTAGTTTACTTTCTTCTATTTCCACAAAATATTTTAATAGTTTTATAAATTCATTATATTCCTTATCCACCATATATTTCTCTACTATTTTATCTATTATACCTTTTATATCTTTAAATAATTCTCTACATCTAAAAGTTAGAAAACCATCTATATTTATTTCATTATTTTCATCAATACACTTCTTAATTTTTTTTATTATTTCATTTTTTTTATTTAAACAATAAATAGAATCCTCTATATATCTTTTATCTCTATCTTTCAAAACATCTGAAATCTTTTCTGATAATTCTTTTATCTCTTCCTGTTTTAAGAAGAAATAATCATCTGTTATAAATTTATTAAGTTCTACTTTTATAAATCTATCTGCAGTTATACCATATAATATATTGACTAATTCATTGTTAATTGAATCTATAACTTTTTTATTTAAAAATTTTTCTTCACAGTATATTTTTATGAAGTGAGTTTTATCTTCTATATTTTCTGACAATCCTATTACCACATTTCTTGACTGAAAACATTCCTTTAATTTTACTAATTTATCAATCAAATCTTCTCTTTCATTATTATAAACCATTGTAAATAACAACATAATCTCACTCCTTTCCTTAAAAATAGTATGTGTCTAAAATAAATTCATATACTAAGCAATTATAAAAAAATATCGACATATTACTCAATATGTTGAAATTTTTTTCAAATAAAACTAATATAATGTTTAGCATATACTTTAAGGAGAATTATTTATGAAAATAGCTTTAGTAGATAACAGAATTTCTAACGAAGAAAAAAACAATTTAGAAAAAAAGAATATAAAAGTGATATTGTGCCCTTCTAGCCCACTTCTATATCCAGCTGTATGTGGTCATCCCGACATGCTATTACACATAATGGATAATAAAAATATTATTTTACATAAAAATATGGATAAAGAATTTGTAGAATTATTAAAAAATTTTGGAATTAATGTTATATTATCTAGTAATTCTTTGAAAGATAAATACCCTAAAGATATAATGCTAAATGCATTAAATATTGGAGATATATTTATGCATAAATTAAATTATACAGACCCTACTCTACTTTCTTTCATAAAGCATAAAAAATTATTAGATACTAACCAGGGGTACTCTAAATGTTCTACTGCTATAGTTTCAGAAAATGCTGTAATAACCAGTGATATAAAAATAGGAAAAATACTTAGAGAAAATTATATAGATGTACTTTTATTACCACCAGGCGATATAATTTTACCTGGTTTAGATTATGGTTTTATTGGTGGTACCTGCGGACTTTTAGATAATAATACCCTTGCTTTTTATGGAAACTTGAATATGTATAAATATGGTGATAAAGTTATAAACTTTTTAAAAAAACATAATGTAAAGCCTATATTTTTAAGTAGAGGTAAATTAATAGATAGGGGTAGCATTTTTTGTATGGATATTAAGTAAGATTTATTCTTCCCCTTTCTCCAGCTTAATATAAGAATCCTGTTTAACTCCATGGAAGTATTTAAACTAAATTAAGATTTAATTTTAATTTAGTAAATATAAAAAATACACATCATAAACATATGATGTGTATTTTTTTGTTATACTTATTAAAATTAAATATATTTTATTTTGAAATACTCTATTTTATTTACTTCATCTCTATTTTTTCAAATATACTTTTAGATAATAATATCCCTATAAAACTAATAAGACAATTATATAAAATCATAGCAAGATACATAGAAACTGTTCCAAATAATCCTTTATACTTAAAAGAAATTAGTACAGATATTATTATTCCTGGTAATACTGCTATTATTAATAAAATAAATTTTAATGTAGCTTCTACAGCTTTACTAATATTACCACCAAAAAATCTTCTTAAAACCAAATCCACATATACAAATATTGCTCCAAAACTTACATAGGTTAATGTAGCTAACAATATAATCGCAGGATTAGTTTTAAATATGATACCACAAATTAAAAATAATACGAAACCATCCACAAAATTTTTAATATGGTTGGTAAGGGTAGCATAGAAAACTTTAATTTCTGAACTCTCTGGAATTAAATATATATAAGGCTTAGACAATTCTTCAGCCCATTTACCTTGAAATGTAAATATCAATAACATATATATTGCAAAATACATTACTGTATTTATACTGCCATTTTTATCAGTCATAAAAAATCCAAAAACTAAGGAGCTTACTCCCATTACTAAGGTCATCTTATCTACAAAGAAAAATCCACTTCTTTTATACTCTAAAACTTGTCTTTCAAATATACTTTTTGCTCCCTTTGATTTTAATATCCCCATAACATTTTTTCTTTTTATAGGTTTATTTAAATCTACATTTCCTTTACCTTTTTTAGCTCTCTCTATCTTTCTTTCATTGACCTCTGTAACTGACATAGCATCTTCATAATAATCTGTTTTTAAAATATACACTATATATATTATAAAAATTATAGATAAGAGTACCCCTAGTAGGTTTATAAAGAATAACTTATTTATACCCTCTATAGCGGCATTAAATATATTTATATTCCATCCTATAAAAGGTATTTGGGAAAACATATCTAACCCTAAAAAGGTTATAAAAGCTAATTTTATAGATTTTACTTTAAATAACGTCCATAAAAAACCTGCTCCAAATAGTCCTAATAATAAATTAAGAATATTTTTTATAAAATTTCTATATTTATCTTCCTTAGCAGCTATAGAATAAATTAGTACAGCTATAGTTGAATAAGAAAACATCAACATGAATATACCCACTACCACAGGTATGGCACCGTGTTGCTTTATAGGAAATAAATTATAAAGATTAGGTATTTGAAATAAAAGAAATACTATCATCATCATACTTTTATATAATTCTTTTAAGAACCCATAAAGCAATACTCTTTGAGGTGGTATAGGAGCTGTAAACAAAAAATTCACATCACTTAATCTAAAAAAACTTTTACCCTTTTTAGTACCTGTATTAATAGCACTAAATACTGCATATAAAGTTACTATAGTAACTATAGCATTAAAAAATTCTTTACCATCTTTTATCCTCTTATTACCACTTGATTCTGGAGATACAATTAAGATAAAAACTAAAAGGGCTATAAAAAGCACATATAATATAGCTTTAGCAGGTTTATTCTTTAGTTGTTTAAAATAATTTTTTATACTTTTTCTAACTATGTAACTAAGTGATCCCATATTATCCCTCCGTTACTTCAAAGAATATTTCTTCTAAGGACTCATTTTTATCTATTAATTCTTGCTTGGTTCTAGCAAAGACTATATTCCCTTCTTTCATTATTAATGCCTTATCCCATATTTCTGATATACTGTCTATTATATGAGTACTAATAATCACTGCTGTTCCTTCTTCTTTTAATTCTAAAAAAACTTTTTTAATTCTTTTATGGCTTTAGGATCCAATCCTATCATGGGCTCATCAAATAATATAACCTTTGGATTAGTAATTAAAGCTGCACATATACTAACCTTTTGCTGCATACCCTTTGACAATTCAGAACCAAGCTTATCTTTTTTATCCCACAAATCAAATCTTTTTAACATATGCTCTGCTTTATCTTTATAATCCTTTACCTTATAAGCATTAGCCATATACTCAACATGCTCATAAACAGTTAATAAATCATATAAAGCTGGAACTTCTGGTACATAGGCGAATTTAGATTTAGCTCCTAAACTTTTATTATCTTTGCCACAAATACTTATCTCTCCTTGAAATTTTAAAAGTCCTGCAATAGCTTTTATACTTGTACTTTTCCCTGCTCCATTTGGTCCTAAAAGCACTGCTATTTCCCCTCCATTAACATCAAAAGAAACATTGTTTACTGCTTTAAATTTATTGTAATTTTTACATAATCCTTTTACAACAAGCATTATTTACCCCCCTTAAAATAAATTTTAAATAAAAAATATTAATATATATCTTTTATGTAATATATATAATGCCAAAATAAGGTTTGAAATCTATATTTCAAAATATATTATAAAATAATCTAGACTGTCAAGTGATATAAATAAAACAGTGACTAAAGTAATTTTTATTATTAACCATACCACATTCACATTTACTCATACTATATATTAATTTATACATTTAATACTATTATCCTCAACTAAAAACTTACCTTCTTTTTTATACTCATTATAAGCATAAAAAAAAGAGATAATATTTAAATATTATCTCTTTTTGGAGGCGCCACCCAGATTTGAACTGGGGATAAAGGCTTTGCAGGCCTCTGCCTTACCACTTGGCTATAGCGCCAAAAAAACATGGAGCGGAAGACGAGATTCGAACTCGCGACGTTCACCTTGGCAAGGTGACGCTCTACCACTGAGCCACTCCCGCAATCTGGTGGCTCGACCAGGAATCGAACCAGGGACACGAGGATTTTCAGTCCTCTGCTCTACCGACTGAGCTATCGAGCCATATGGCGACCCAGAAGGGGCTCGAACCCTCGACCTCCGGCGTGACAGGCCGGCACTCTAACCAACTGAGCCACTGGGCCGTATTTGGTGGGCACAACAGGGCTCGAACCTGTGACCCCCTGCTTGTAAGGCAGATGCTCTCCCAGCTGAGCTATGCGCCCTCACCAATTACAATAATTATTATATTATAATTGGGCACTAATGTCAACTAATAATTGGTCAATATTATTTTTCACTATAATAATTTTCTAAAATATCCCCAACCTCATCATGACTAAAAACATATGCTTTATTACAAAAATGACATTTTAATTCTTCCTCTTTGCCTTCATCATATATTTCTTTTAAATCCTTTTGTCCTATACTTGCCAAAGCTCTTTCTACCTTTTCTCTTGAACAATCACATCTATATTCCGGTGCTATGCTTTCTAATATTTTTAAATCCATATCTTCAAATATGTATTCTAATATTTCCTCTATTGTCATTCCCTTTGAAATCATTTCTGTAATTGAAGGTATTTCTTCTAATCTATAACTTATTAAATCTGCTAACATTTCATCAGCCCCAGGCATCATTTGTATTATAAACCCTCCAGCTGATTTTATAGATAAATCTTTATCTACTAATACTCCTAAACCTACCGCTGAAGGAGTTTGTTCTGATACTGTATAATAATAAGCTAAATCTTCTCCTATTTCTCCAGTATATATAGGTACCTGTCCTATATAAGGCTCTTTCAATCCCATGTCTCTTATAACTAATAAGTTACCATTTTTACCTATAATTCCACTTACATCTAATTTTCCCTTACTATTTGGCTCTATATCTGCTGTAGGATTACCTATATAACCTTTAACATGCCCATCTGCATATGATGTAACTACAACTCCTTTAGCAATACCACCACCATGAATTTGTAGTGTTAAAGTGTCCTTTTCTGATTTTAATGTAGTTCCCATTAATGCTCCTGCTGTAAGCATTCTTCCTAAAGCAGCAGCTGCTGTTGGAGCACAATTATGTAGCTTTACTCCTTCATTAACTAATTCTGTTGTTATTGCCCCTATTATTCTTACCTGTCCATCCTTAGCAATAGCCTTAACTAATTTATCTTTCATGTAAATTCACCTAACCTTCATCATTTTAATTAAAAAACTATTTAGTCAATATATAAACTATTCTTTCTGTCTTTTCTTGTATTTTTTTATTCTCATAATTATCTAAGGTTCTTAATATTTTAAATCCATTATTTAATATAATTTCTTCTATTTCTTCTTCTTTATAAGCTCTTTCTTTGTGTTCTTCATCAAATCTTATATAATTATTTTCATCTTCCCTTATAAAGAATGTAATATCCATATTCGTGATATTATTTTCTGTAGAGTTTCTCCATATATATGTAATCTCATCATCATCATAGCTGAAAAGATTATTTCCTAAAATATTATTTAATTTATAGTAAGAATTTATATCAAATATAAATAGCCCATCTTCTTTTAAATGATTATACACATTTTTAAACAGATTATTTAATGATTTTTTATCCAATATATAATTTATACCATCCAAACAACAGGTTATTAAATTAAAAGTTTTATTTAATTTTAAATCACATATGTTTTGACATACTAATTTACCTTTTATATTATTTTCTCTAAATTTATTCTCAGCTTCAGTTAACATATCATAAGAAAGATCTACAGCCCACACATTTTTAAAATACGGTGATACTTGTAATGTTAAATTTCCAGTACCACAAGCTAGATCTAAATAATCTATTTTACATAAATTAAACTCATCACATATATTTGTTATAGTTTTAGCCCATTTTTCATAGTCTATATCCTCATTTATAAGTTCATCATATATATGGGCAAATTCTCTATAACATTCCATTCCTAAACTCTCCTTAATTTATAAAAATATACTTACCTAATAAATATTATATACTTTTATTAGGTAAGTCAATAGATTAGTGCTTCTATTGCATACTATTTTTAATTTCACTCATCATTAATATTTCTTCATTTTTAGGAAGTTTAAGCTCTTTTTTTCTTTTGGTCATTATGCCCCCTATTCTTCCGGTTTCTTCTGAGGTTAGTCCTCCCCATCCTAATTGGTCTACTTTATCTTGTAGGCCGAGCTCTATTGCTATTTCGTACTTCATTTTTTCTCTTAATTTTTCTTCTTTAGTAAGCTCCTTGTTAGCTTTAATTTTGGATTTTATTACTTTTTTTAAAGGAGTCTTCGTCATTTAAATCCCTCCATACAAATAATTTATTATTACTATTATTTGCCTTGTAGGGGTATTTTATACTATTATAAAAAGAGACTGAAATGCCAACCTCTTCTTTATTATATATTATTTACTTTCTATTCTTCATTAATATTATAATTAAATTTACTTTACAAAATTATACCTTTTATATTTACACCTTCTACATTCAAACAGTTCAAACATAAATTTAAAGAGAAGTATCTCAAAATACATACAATTTTGAAATCCCTCTCTTTTTAAATTTATTGTTATCATCTATACCATATACATATTTTTTAATCAAATAAATGACAGGCTACAAAATGATCCTTTTCTATTTCTTTAAGTTTTGGTTTTTCTTTTTTGCAAGTTTCCTTTGCATATTTACATCTTGCTGCAAATTTACATCCCGGTTTAGGGTTTATAGGACTTGGGACTTCTCCATGAAGCATAATTCTTTCTCTATCTCTGCCTACCTTAGGATCTGGAACAGGTATTGCGGATAATAAAGCCTTAGTATAGGGATGAAGTGGATTTTCATATAATTCTTGGCTATTAGATAACTCCACCACATTCCCCAAATACATTACCCCCACTCTATCAGATATATGCCTTACCATAGAAAGATCATGAGCTATAAACAAATAAGTAAGCCCCAATTTATTTTGAAGGTCTATAAGCAAGTTTACAACTTGCGCTTGTATCGATACATCTAAAGCTGATATAGGCTCATCACATACTATAAACTTAGGCTCTATAGCTAAAGCTCTTGCTATTCCAATTCGCTGCCTTTGTCCACCTGAGAATTCATGTGGGAATCTAGAGGCATGTTCTTTATTTAATCCAACTAAACTTAACAATTCATATATTTTATTAAGCCGTTCTCTTCCTGTATAAATCTCATGAATATCTATACCCTCTCCTATTATATCCGCAACTGTCATCCTTGGATTTAAAGAAGCATAAGGATCTTGGAAAATTATTTGTGCTTCTTTAGTAAACTCTCTTTTTTCTTTTTTACTAAAGTCGTGAATATTTACACCTTCAAATCTAACTTCTCCCTCTGTAGCTTCATATAAACCTAATATAGTTCTTCCGCAAGTAGTTTTACCACATCCTGATTCTCCAACAAGTCCTAAAGTTTCCCCTTTTCTTATATCAAAACTTACCCCATCTACGGCTTTTAAAATGGCATCCTTTCCGACCTTAAAATGTTTTTTTAAATTTCTAACTTCTATTAAGTTTTTACTCTCCATTATTTTTCACCCCCAGGTAAAAAAGAACTATGAACTTTAGGTGACATAGGATGCTGTAACCAGCAAGAAACCTCATGAGTTTCTGTTAGCTTTGTTACTTTTGGCATCTGTTCTTTACATATTTTCATGCAATATTCACATCTTGATGCAAAGGGACATCCTTTTGGTGGTTTAATCAAATCTGGAGGAGTTCCTTCTAAGGAATAAAGCTCTCCCTTATGCTTTGTATCCAATCTTGGTACCGATTGAAGCAATGCCCAAGTATAGGGATGCTTTGATTCATAAAATATTTCATTTGTAATTCCTCTTTCTATAATTTGTCCCGCATACATAACTTGTATTCTATGAGCTGTATCCGCAACCACCCCTAAATCATGAGTTATCATTATAACTGCTGTATTTAATTTTTTTTGCAAATCTCCTATAAGATTCATTATTTGAGCTTGAATAGTAACATCTAATGCTGTAGTAGGCTCATCTGCTATAAGTACTTTAGGATCACAGGCTAAAGCTATGGCTATCATAGCTCTTTGTCTCATTCCGCCTGAAAATTCATGAGGATATTGATTAGCCCTTTTTTCAGCATTAGGTATATTAACTAATTGCAATATATTAATGGCCTCTTTAAAAGCTTCTGATTTATTCATTCCCCTATGAATAATTAAACTTTCAGCTATTTGTTTTCCAACCTTCATTGTAGGATTAAGAGAAGTCATAGGATCTTGAAATATCATACTTATATCAGCACCTCTTAACTGTCTCAATTCCTGTTCCTTCATATCTAATATATTTTTATCATTAAAAATTATTTCTGATCCTTCTTTAATTTCTCCTGGTGGTTCTTGTATTAATCTCATTATAGCTTTAGCTGTCACAGTCTTTCCACATCCTGACTCTCCAACTATGGCAAGGGTCTCTCCTTTATTAAGATGAAAGCTTATATTTCTAACAGATTGTACTTCTCCCGCATAAGTATGATAAGAAACTCTTAAATTTCTTACCTCTAATATTCTCTCCATCACATTCCCCCCTTTATTGACGCATCTTAGGATCAAGAGCGTCCCTTAATCCATCGCCTAGTAAATTAAATGATAGCATAGTCAAACTTATAAACAAAGCAGGGAAAAACAATTGATAAGGATAGAACATTAGATTTGGTTGTGCCGCTGATGCCAAAGAACCCCAGCTAGTATTTGGTGATTGTATACCTAGTCCTATATAACTTAAAAAAGCTTCTCCAAATATAAATGATGGGACATCTAAAGTAATATTAACAATTAATATACCCATAGTATTGGGTAATAGATGTTTCTTTATTATTCTTGAAGGCCTAGCACCTAAAGCTTGAGCTGCTAATACATACTCTTGCTCTCTTATTTGTAGAATTTGTCCTCTTATTATTCTAGCCATACCACACCAACCAGTTATAGTCATAGCTATTACTAAAGATATAACCCCTTTTCCCAATATAAGAGAAATTATAATAACAACTATTAAATAGGGAACACTTAGCAATATTTCCACTATTCTCATCATTATATCATCAACCATTCCACCAAAATAACCGGATATTCCACCATATATAACTCCAATTGTCATTTCTATAATAGTTCCTAAAATTCCTATTATTATAGAAACTCTTCCACCCTTCCATACTCTAGCAAATATATCCCTGCCTAACATATCGGTCCCAAACCAATGATTAGAATTAGGGGTCATATTCACAATATTAGAATCTGTAGCCCAATATTTATATGGGGTTAAATAAGGTCCTATTATTGTCATTAAAGCTATTAATATAAGTAATATCAATGACCCTATGGCTACCTTATTTTGCTTTAATCTTCTCCAAGCATCCTGCCAATAAGTTATATTAGGTCTATTTATTTCATTAGATGCATTTTTATCTATTCCTATTATTTGAAATTTATCTTTACTTATTTCAGCCATTTTTCTCCCCCCTTATCATTTTGAGTTTGTAATCCTAATTCTTGGATCTATAATTCCATATAATATGTCTACAATTAATAAAGAGAATATATAAAGGGTAGCCATAAATACAGTAAGCCCCATAATCATAGAATAATCCATATTATTTACAGCTCCTACAAAAGAACTGCCTAATCCTGGTATGCCATATATACCTTCAATAACAAAGGATCCTGTTAATATAGTTGCTATTTGAGGACCTAGTATAGTTATACTAGGCAAAATAGCATTTCTTATTATATGTTTCCAAGCTAAAGAAACCTTTGATACACCCTTTGCTTTTGCTGTCAATATATAATCCTGTCCTAAAACATCTAAACATTCATTCCTCATATATCTTGCATATATAGCTAAAGGACTTAAACTTAAAGCTATCGTAGGCAGTATAGTATACTTTGCACCACCCCAACCAGTAGTTGGCAATATCATAAATTTAACTGTAAATATATATTGAAGTAGTGCTGCAAAAACGAAACTTGGTATAGAAACACCAATTAAAGCTAAAAACATCACTATATAATCTGGCCATTTATTCCTTTTAAAGGCTGCCACAACCCCTAATATTATTCCTAATGTAAACCCTAAGAATACTGCTTGAATACCTATTCGTGCTGATGCTGGCAATCCATCTTTTATAACTGTATTTACACTTCTTCCTGCAAAAGCTAAAGAATCTCCTAAATCACCTTTTAATAAATTTTTCATATAAACTGCATATTGCGTTGTTAATGGTTTATCTAATCCATATTTAGCATAATAATTAGCTCTTATTTGTGGTGGTAATCTTTTAGCGCTAGATGCTAATGGATCTCCGGGTATAGTATGCATTAATACAAAGGTTATAGTTATTACTATCCATAAAGTAAGTAGCATATATCCTAATCTTTTTAAGATATACTTAAACATCTTTATCCCTCCCCAATATATTTTTATGTAACTTATAACAGCAGAGCCATTAAAAGGCTCTGCTGCATAAAATCATACTATTACTCCCTACCTTCCGTATGGGCATATTTAACATCATATAAAGAACCGAATTGTGGAACCATTATTCCCTTTACATATTTTCTTTGATAAATATTTCTAGCTCTATAAACTGCTGGTGCTATTACAGCATCTTCATATAATAATATTTGTTCAGCTTCTTTAAACAGTTTCATTCTTTCTTCATTCTTTTCTTCTGGTAGCAATGCAGCTTTTTTAATTAATTCATCATATTTTGTATTTGAGTAATTTGTTGGAAGCGCTTTGGCCCCAGTCATCCACAAATCAAATTCTGTCATAGGATCATCATAATCTCCTGTCCAAGCCATACCTGATATTTCATATTCCGCATTATTTATTCTCTTCATGTATACTGGCCATTGAACATATTCTATGTTTACTTTAACTCCCAAAGCTTTTTGATACATCTCTTGGAAAAATTCGCAAATTTCTTTTTGTTGATCACTTGTAGAGCCTGTTAAATAATTTACTGTTACTTTACTTGGATCCGTATCCATTCCTAATTCTTTTAATCCTTCAATTAAAAGTTTCTTTGGATCTTGATTTTCTTCTTTTAATTTCTTAATTGGTTCTTCTCCTGCTTCTTTTCTAAATTCTTTATCTCCTATTTGTAATGAAGGTGGCACAAACCCATAGGCTGGTGTAAAATCATTTTTAAATAAAGTTTTTGAAACCTCTTCTCTATTAACTGCTAAAGAAAAAGCTTTTCTTACTTTAGCATTACTAAATAATTTAACATTTTGATTAAAGAATTCAATATTTGTTGCTGGTTCAATAACTTTTTTCACTTCAAATTTATCAGCTTTTTTGAACTTTTCTTTCCACTCTGGCTTTTGAACATTACTGAAATCTATTCCTCCATTTAGAAGCTCTTGCATTCTAGCAGCTTCATTATTTATAATTTTCATATGAACGTTATTTAATTTAACAGATTTAGCATCCCAATATTTTTCATTTTTAACTAATTCCATTTTGTTTGCATGTACCCATTCCTTTATGGTAAAAGGTCCACAGAATACCATATTAGAAGCTTCTGTACCAAATTTTTCTCCATACTTTTCAACTATATCCTGTCTTTGTGGCATCATTAATTTAAAATATGTTATCTTTAAAAAAATATGCACAAGGTCCAGCTAAAGTTATTTCTAAAGTTTTATCATCTAAAGCTTTTACTCCAACTTCTTCATCTTTTGCTTTCCCTGCATTATATTCGTTCGCATTTTTTATTGGAGCTAATAAGTAAGCATACTCTGATGCAGTTTTAGGATCTAAGTTTCTTTTTATTACCATATTCATAATCCTTTGCAGTAACCTTCTTTCCATCAGACCACTCATAATCTCTTAAATGAAAAGTCCATTTTAACCCATCCTCAGATACATCCCATTTTTCTGCTCCTGCTGGTTTAACTACATCTTTACCTTTTTCATCTACTTCCAATCTTGTTAATCCATCATAAACCTCAGAAATAACCTGTGAAGAATACAAGTCTGTTGATTTAGCTGGGTCTAAACTTTTAGGTTCTTCCTGCAAAATCATATTTAGATATTGTTCTTTATCTGCACCTTTACTTCCTGATTCAGTTTCCTTTCCTCCACATCCTGCTAATGCTACCGAAGTTAAAACCACACAAGATACTAAAGCCGCCAATAACCTTTTACTTTTCACTAAACTTCCCCCTTTAAGTTATTTTATAAAAAACAAGTGAAAATTCACTTATTTCCAATAAAAATTATTTTAAAATAACTATATTTTAAATATGTTTTCTTTTATTTTTATACAATATGCAAGTAAACACTTATTGATGACACTTTTTTGCAATTTTTAAAAAATTGAATTTAATTTTATGATTCAATCATATTACTATAGCTTATTTTTATATGAATTTACAATTACTTACAGCAAACCATCTATTTGCCTCACTTATATCCACCTAATGTTTCCTTAATTTTCAGTAAATTGAATAATATTTTTCTTATTTAATGTATTCTGCACTATTAAATTTAAATATTATAAATAAATGAAATAATGGATTTTTATTTATTTTTATATAACAAAAAGCCTATATATTTTTTAGCTAATCAGTTATATAATATTATTAACTATAATAAATTATATGATTATTTAATATTCATTTGGGAGGTATATGTTATGAATTACAATGTAGCAGTAGTAGGGGCTACTGGAATGGTAGGAAGAAAATTTATAGAGATTTTAGAAAGCAGAAATTTTCCTATAGAAAACATTTATTTTTTTGCTTCTAAAAGATCTGCAGGTAAAACCTTAAAATTTAAAACTTCTGAAATATTGGTAGAAGAATTAAAAGAAGACAATATAAAAAATAAAAAAATAGATTTTGCATTATTTTCTGCTGGTGGAGATATAAGTAAAGACTTTGCACCTGTTTTTGTTAAATATGGTGCTACAGTAATTGATAATAGCAGTGCTTGGAGAATGGATCCTGAAGTTCCTTTAGTTGTTCCTGAAGTAAATGCTGAAGATATAAAATGGAATAAAGGTATAATTGCTAATCCAAATTGTTCAACTATACAAGCTTTAGTGGCTTTAAAGCCTCTTCATGATAAATATAAGATCAAAAGAATTGTATATTCAACTTATCAAGCTGTATCTGGTGCTGGATTAAGTGGTTTTAATGATCTTAAAAATGGCTATACAGGAGAATCACCAAAGAAATTCTCTTACGCTATTGCAGGAAACATATTACCACATATAGATGTATTCTTAGAAAATGGATATACAAAAGAAGAAATGAAAATGATTGATGAAACTAAAAAAATGCTTCATGATGATACTCTAAAGATAACAGCAACTACCGCCAGAGTACCTGTATTTCATGGACATAGTGAAAGTATAAATGTAGAGCTTGAAAAACCTTTTGAATTAGAAGATATATTTGAAATTTATAAAAATGCTGAAGGTATAGTGCTTAAGGATGATGTAGCTAATTTAGTTTATCCTATGCCTATTGATGTAGCTGGTCATGATGAAGTGTATGTAGGAAGAATAAGAAGAGATTTTAGTCTAGATAACGGCTTAAATTTATGGGTAGTAGCAGATAATATCAGAAAAGGTGCTGCACTTAACGCAATTCAAATAGCTGAGCATATAATAAAAAGTAAGTAATTAAAATTTAGGAGGTATTTTTATGAGTATTTTTAAAGGTTCTGGAGTAGCTATAATAACTCCTTTCACTGAAACAGGAGTAGATTTTGACAAGCTTTCTGAACTAATAGAATGGCATATAAAATCCAAAACTGATGCTATAATAGTTTGCGGAACTACTGGTGAAGCAACTACTATGACTGAAACTGAAAAAAAAGAAACTATAAAGTTTGTAGTAGATAAAGTAAATAAAAGAATTCCTGTTATTGCAGGTACAGGTAGTAATAATACTGCCGCTTCCATAGCTATGAGTAAATGGGCTGAAAGTATAGGAGTAGATGGACTATTAGTAATAACTCCATATTATAATAAGACGACACAAAAAGGATTGGTTAAACATTTTAGAGCCGTTTCTGATGCTGTTAATACTCCTATAATCATATATAACGTACCTGGAAGAACAGGACTTAATATAGCTCCTAGCACTTTAAAGGAACTATGTAAAGATAAAAACATAGTAGCTGTAAAGGAAGCTAGTGGTAATATAAGTCAAATAGCTCAAATTAAAGCTTTATGTGGTGATAAATTAGATATATATTCTGGGAATGATGATCAAATAATTCCTATATTAGCTCTTGGCGGAATAGGTGTCATCTCTGTATTAGCTAATGTAATTCCAGAAGATGTTCACAATATATGTGAACTATATTTAACTGGGAAGGTTAATGAAGCTCTAAAAATTCAATTAGATTCTTTAGCTCTTACTAATGCTCTATTTATAGAAACAAATCCTATACCAGTAAAAACAGCAATGAATCTTATGAACATGAAGGTAGGAGATTTAAGACTCCCTTTATGTGAAATGAATGAAAATAATTTAGAAATATTAAAGAAAGAATTAAAAGCTTGTAACTTAATGTAATATAAAGTGTAGAGTTTATCTCTACACTTTACTATTAAGATATCTAATAAAATAAATTTAGTTTATCCGATGACTACCCGCTCTAATACTCCCATCTTCTTCAAAGTGGGACTAAAGAGCGGCTATGTCCCTGGATAACGATTTCTAAGCTTTAGTGGAAGTAAAAACTCCCTCTGAAGCCAAGAACTCTGTTTATATAATAATTTTAGAGGAGGACTTTCAATGGTAAGAGTTATATTAAATGGTTCTAATGGGAAAATGGGTAAGGTTATATGTGATTTAGCAGAAAATTATTCTAATTTAGAAATTGTAGCAGGCATAGATAAAGGTGAGGCAACTTCTTCTTTTCCTGTTTTTACTGATATAAACAAATGTAATATAGAAGCTGATGTTATACTAGACTTCTCAAGACCTGAAGCATTAAATGATTTGCTAAACTTTGCTACTTCAAAAAATATGCCTATAATAATATGCACCACAGGTTTTTCTGAGAACCAAATAAAACTTATAGAAGAAACTGCAAAAAAAATACCCGTTTTTAGATCTGCTAATATGTCTATAGGTATTAATATAGTCAACAATATATTAAAAAACATAAGTGCTTTTATGTATAAAAACTTTGATATAGAAATAATAGAAAAACATCATAACCAAAAGGTAGATGCTCCAAGTGGAACTGCTATTCTTCTAGGGGATACTATAAGGGATTCCATAAAAGAAGATACTAAATATACCTATGGAAGAGAAGGTAGTTCAAAACGAACTCATGATGAAATAGGTATGCATGCCATAAGAGGCGGTACCATAGTAGGTGAACATGATGTTATATTTGCAGGATCCGGGGAAACTATAGAAATTAAACATACAGCTTTATCTAGAGAAGTATTTGCTGTAGGAGCATTAAACGCTTGTTTATTTATGAGTGGAAAAGAAGCCGGATTATACAACATGGATAAAGTAATACAAGCAGCTCTATAACCATAATCTAAGGAAATTACGACGTAACAACCTTTAAAGGTTGAGAATTAAAATAAGAAATACTTTTAGTCAATAGATAGCTATAAAGATAAAGAATACTAATATTTGTGCCCTAATATTTAGGCTAACGCTCTAATGCCACGTCCTGTGGCAGCAGAGCTAAGTAAACGTCCTGTTTACTTCACGCTTAAATATTAGTTCACAAATAAAGTATTCTGATTATTTTTCTAGATATCTATTTTCACTAAAATTATTTATTGCTTTAATACCTTTAAAGAGTTATGCTAGCTTCCCGTGATTTAAAAAATAGGGATATGTGGTGTAAAAAGCATTTGAGCAAGATTAGAGATTCTTATTTGTTTTTGCAAAATATATGAATGTTTCAAATTATTGTTCGAGCGTTCAGCGAGTTATAATTTGAAACCATATATTTTAAGCAAAAACAAATTAGAATCTCTTATTGAAGCAAATTGCCTTTTTAACCATATATCCCTTTTTTAAATCACGGGTAATATATACTCTTTTAAATCGTAATTTCCTTACATTGTGATTTTACTTAACCATGCTTCCATTCTATTTAGTGCTTCATTTAATTCTTCCATGCTATAGGCATAAGATATTCTAATATATCCCTCTCCCATTTCTCCAAAGGCTGAGCCAGGAACTATAGCCACTTTAGCTTCCTTCAAAAGTTTTTCACAAAATTCTTCACTAGTCATATTATATTTTTTTATGGAAGGAAACATATAAAAAGCTCCATTAGGGAGATATGTATCTATACCCATGTACTTTAATCTATCATATACAAAGTCTCTTCTTTTTATAAACTCTTCTTTCATACAATCTACATCTTTCATGCAGTATTTTAACCCTGCATATGCTCCCCACTGACATATAGAAGGCGCACAAGATACATTATATTGATGAACTTTTATTATAGAATTTATGAACTCATCATTTGCACAAACATACCCTATTCTAAGGCCAGTCATTGAAAACATCTTTGAAAATCCACTAACTAATATAACCTTATCTTTTATATCTTCAAATTGAGCTATAGAATAATATTTTTCTTCAAAACATAAAGAGGCATACATTTCATCACTTATTACTATAATATTATTTTCTTTTATTATTTTATGTAACTTACAACTTTCTTCTTTAGAAAGTATAGCCCCTGTTGGATTAGATGGATAAGATAATACCATAACCTTAGGCTTTTCTTTTTTTTATTATATTTTCTAAATCTAAAAAATCTATAGAAAAATCATTTTTTAATTTATAATTTAATATTTCTCCACCTAGTAATTTTACACAACTTTCATAAGCTGGATATGCAGGTGTTGGTATTAAAACTTTGTCTCCTTCATTTAGTAATGTAGAAAATACACACATTAATCCTTCACTACCACCTACAGTTATACATATCTCTTCTGAATTATAATTAATATCCATAGTTTTAAGATATTTTTCTATTTCTAATCTTAAATCTTTTAATCCTGCATTAGCTGTATAGGTTGTTTTATCCTCTTCTATAGACTTTACTAATTCCTCTTTTATTCTATTTGGAAGTTTAAAATCTGGTTGCCCTAAAGTTAAGGAAATAACATCCTTATAATTTGAAACTTTGTTAAAAAACCTCCTTATACCAGAAATCTCTATATTTTTAACTTTTTCCGAAATAATTTCTTCAGCTTTTATATAATCCATAAAATATTATCATGTTATGGTAATGTTAATAAACCATAACCTCTCCTTCCTTTCTATATTTTTACAATATTAAAACCAATATGTTTTATTAAATTTACATAATAATTTACAATATTCGAATCCATATCTTATTAATGCTTTTATTTCTAATATTTCTACTTATTATACTATTATTTTCATGTATATTGAATACCCCCCTTTATTTAAACATTAATATTTATTATAATAGTGTTATTATAAAATAAGGAGGAAAGATAATGAGTTACAATTTAACAGATCCATATGAAATAGCTAGATACATAAAAGAAGCCAAAAAATCAACTCCTATCAAAGCTTACATAGAAGGAGATCTCTCAAACTGTGATTTTACGAACATAGAAAAATTTAATAGTGGAGATTTATATATATTATTTGGTGAATCAGAAGAAATATTAGTTATTATAGAAAATAATAAAGACAAAATAAAAAATTGTAGAATAGAACAAGATAGAAGAAAATCCGCAATTCCTTTACTTGATATGCTTAAAGTAAATGCTAGAATAGAACCAGGTGCCATAATAAGAGACAAAGTTTTAATAGGAGAAAATGCTGTTATTATGATGGGCGCCGTTATAAATATAGGTGCTGAAATCGGAGAAGGAACTATGGTAGATATGAACGCTGTAGTTGGTGCTAGAGGAAAGCTTGGTAAAAATGTACATTTAGGTGCCGGTGCTGTAGTTGCTGGTGTTTTAGAGCCACCTAGCAGTGATCCTTGTACTATAGAGGATAACGTTCTTATAGGCGCAAATGCTGTTATATTAGAAGGTATAAAAATTGGTAAAGGTTCTGTAGTGGCAGCAGGGTCTATAGTTACTACTGATGTACCAGAAAACGTAGTAGTGGCTGGTGCTCCAGCTAAAATAATAAAAGAAGTAGATGTAAAAACTAAAGATAAAACTAAGCTTTTAGATGATTTAAGAAAATAAATTTATGAAAGATAGTTTTAAAACTATCTTTCATATTTGATAAAGTTTTCTATTAATTTATTTAAATATACTTGAGAATAGTATGTACAACTTAAAAAGTTGTACATACTATTCTTTATGCATGTTTTTCTTTTATATTATCCATAAAATCCTTTTCTTCATAACTTTCTTCATAATCATTATCCCCGGCTTGTTCATCTCCTACTCTCTCCATCTTTGATATAGAAACCTCATAAGCTACTTTAGTAATAGTTTTATCCTCTGAAATTCTCTTTTGGTAATATCTACTTTGTAATCTTCCCCAAACTCTTATATTATCTCCTACTTGTAAAGTTTTACAAAATCTAGCATTTCTTCCCCAGGATATATTAGGGATATAATCTGACTTGTTATAAGGTCTATTTACTGCTAATAATAAATCAGCGATTTCCCTACCAAAGGGAGTTGTCCTATATATAGGCTCTTTACATATATATCCATCTAAAAATATTTCATTAGGGTTTTTACTTCTTTCAATACAATATTCTATGTTTCTAGCAAATACAGTTAATATAAGTCTATTGCTGCCATCTACAAATTTATTATAAGATCTTAGCTGACCCTCTACTATAATATCCATACCTACTTTTAGTTCCATATCCGCTAACAATCTTTCAGATACAGTTATATTTAATATATCTGATACATCGCTTAATCTTGAAACTTCCATTTTAAAATTATAAAATCCTTCTCCGTACATTTCGTGACTGAATTCTAAATCCTCAACCACTGTTCCCTCTAAATAAATTTTATTGTTTAACATTAAATTGTCCATCATAACCCCTCTTTCCCTTAGTTTCAATTCATTCATACAACATATATTTATTATTTATATATCTAAAATATGCCATAAAATTAAAACTTATTTGTAGAATTAATTATTTTACTCTCTATATTGGAAATATTCGCTCCTTGTATTAAAGCAATAGTTATAATAACCATATAAGCATAAAGACAACTTTCATCTTCATAATAGATGTTTAATGGCATCTCTTGTGGTTCTATTATATTTTCATTGTATATACTTATATATCTTTGAATACAATAAACGATTCCTATATTCTCTTGTTCCAAACTAGATAAAGTAATAGTGTTTTTATTTCCCAATCCATAAGTTATAACAACACCTTTTATATCTACATTTTTATTTTTAAACAAATCCATATTTATAAAACAATATTCACAGTCTATTCCGTCATATTCAAAATTAATATCTCTATTTATTACTATATATTCACTATTCGCTAAAGTATTTTCCCTTGAATAGTGCAAATCTAAATCTAATATTTTTATCATATTATGAATATGTCTTACAAAACTTTCATCTTCTGAATATATACATATTTTTTTCATTTTACACGCTCCTAAAGAAAATAACTATTTTTAGTTATTTTCTTCAGTTTACAATATTTTATTCCCCTGTAATTTTATTATTCATTTATCATAATATTATATCTTTTGTATGTTAACCCCCCTCTTTAGTAAAAATATTACACCTATACTACATTTTCTATATTTTTTTAAATATTCCTTCATTTTATAATTTAAACTTTAATTCTTTTTTTGTACTCCTGCTGAATCTATATAATAATTTTCTTTATATATTAAATCTCCTACTTTGACAAATTCAAATCCATTTCCTTTTAATTCCTTAATTATTCTTGGTAAATTGTCTGGAGTGTATTTAGCTGTATTATGGAAAAGCAATATGGAACCAGGCTTAGTCTTTTTTATAATTCTTTCATATTCTAAATCAGCTCCTTCTTCTTTCCAATCGATACTATCTACATCCCATTGCACAGAATATAATCCTATTTCATTTACTGTATCTATCGCTTCAGCATTATATTCTCCTGATGGAAATCTAAATAATTTAGTACCTTCTCCAGTTATTTTTCTTATACTAGCATCATTAATGTTAATATCTTTTATTATTCTTTCTTTAGATATTCTACTCATATTAGGATGACTATGAGAATGATTTCCTATTTCATGTCCTTTATCATGAATTTCTTTTACTTTTTCTGGCTTTTGCTCTATCCAATCTCCCACTAAAAAAAGGTAGCCTTAACATTATTTTTATCTAAAATATCTAATATTTTATCTATATATTCATCCCCTCTGCTGACATCAAAAGTTAAAGATATTTTATTTTTCTTTTTGTATCAACTCTATATATAGGAACCTTCTTCGTAATATTTAATGAAACTTTTTGACCTCTACCATTAATAAAAAAAGACATACTTATAGCTAAAACTAAGAGTAGTAAAGAAAATACCATCCTTTTTTTAAATTTATCCTTCATTTTATTCCTCCAAACTAAATATTTCTTCATTTTTATTTATATAAAATATATTTTTTTATATGCATTAAATAATTATTTTTTATTTATTAAAGTAATTTACACTTAATTTTTATGATATAATTATATATAAATTATTTTAACTAAACTTTGGGGAGGAAATTTGATGTTTGATGATGCTTTAGAATTAGCTGAAAATAAATTGCTGATTCTTTATGTATTTAATAGATTAGACCTTTCTATCTCTAATAATAAAATAACTGAAATTATATTAGAAAATAATCTAATTAATTATTTTACTTTGCAACAATATCTATCAGAACTTGCATCTTCTGGCTTTATTAAGAATACAGATCAGCATAAAATAATGATTACAGAAAAAGGTATCCGTGTTCTATCAATGTTTATAGATAGAATTAATGAAGATAAAATTGAATCTATAAATAATTATTTAGACTCTAAATTAAATTCGATAAAAAAAGAAGTTAATATCATGGCTGATTATACCTTAGAAAACAAAGATACCTTCTTAGTAAGTTTAAAAGCCACTGAAAATAACTTCTTATTAATGGATATAAAGTTATCTGTAAATTCAAATAAAGAAGCAAAGGAAATCTGCTCTAAATGGAAAGAAAATTCTAGTGCGATGTATACAAAAATATTAAACATTTTAAGATCAACAAATGAAAACTGATATTATAATACTAAAATACCTGTAGGTTCTCCACCTATAGGTATGGATTTTTTATTGTTAGTTCTAATATTTATCCTTAAAAATAAATTTTTATAATTATCTCCCACGTAAATATTATCTTTTATCTTACACACTCCTCTTGGCATACCACCAACAATTATATCTTTTATTTTTTCATAATAATTTATATCAATTAAACTAATAGTACCATCTCCAAAATTAGAAACTATACATAACTTCTCATCAATGCACATATCAACGGGTGAATTTCCTACAGGAATTCTATATAAAAGTTTATAATTTTTTCTAGATATTATACTTATACTTCCTTTATAATCAGAACCTAAATTACTTTCACATACTAATATATATTTGCCATCTACTGTGAAAACAGCTTTTGTTGGATAAGATCCAACTCTTATATTTTTTACTCTATTTTCTTCTTTACAATCTATTAATGTTATATTATCTGTCCCCATATTTGATATCATTAATATTTCATTTTGTTTATCAATAACTATGCTATGTGGTAGATCCCCGCAAGGTATTTGTTTTGAAATTTTCTTTTTAACCATGTCAAATACAGTTACATTGTTTAAATCACCACAAATAACATAGGCTTTATCTCCATATACAACTACATCATTACAATGCATTCCTATAAAATAATTTTCAATTTCTCTTCCTAATTTTCCATCTACTACGGAAAGAGAATTACTATAACTATTAGCTACAAGCAATTTATCATTATATGCACATATACCATGAGGCCCTATTCTAGTAGATAGTTCATTATTTAAGGTTATTTTGTTTTCTTCTTTAAAATTATCTATAGAAACTTTGGAAATACAATCTGTAGATGTATTGCATACATAAACATACCTCATTTTATCACCCCTCGCTCTATAATATAATATGTGAAAAATAACTAATTTGGTGATAAATCTTTTATGTTGAGCAATAAAGTTTTATGTTATATAATGATATTAGTATTGTTTAACATTCAAATTGAAAGGAGACAATAATATGTATACTTATTCACCTATTGGTGTTTGTTCAAAAAAAATAACTTTTGATATTTTAAATAACAAAGTTGTAAAAGTTAATTTCCTAGGAGGATGCGATGGTAACCTTAAGGGATTATCTAGTTTAATAGAAGGTATGGATATTGATGATGCTATAAAAAGATTGCAAGGTATAACCTGTGGTTCTAAAAATACTTCCTGTCCAGATCAATTGTCTAAAGCTCTACAAGAAGCAAAAAAACAAAATAAGGAAAGCATCTAACACTTTCCTTACCTTATTAATTTTCTCATATCACCTACCATGTATAATGACCCACAAATTAAAATCATATCTCCATCTTCACAGTAAAATTTTGCCTTATCATAACATTCTTTATAGTCCTCTAGATGTTCACAACTTTCATTATGTTTTAATACAATGTGCATTAATTCTTTTGAACTTTCCCCTCTATCATTATGAGGAGCTACTGTTAATACTCTATCTGCTAGTGGTACTAATGTTTTTATCATGTCTTCTACTTGTTTATCTTTTAATATGCCTAATATTAAAATAAGTTTATTATATTTAAAATATTTACTCACATTATTTTTTAAGCTTTCTATGCCATCTATATTATGGGCTCCATCTATTACTGTTAGAGGATTTTTATTTACTATTTCTAGTCTAGCTGGCCATTTCACTTTTTTAAGGGCTGATATTATGTGTATTTTTTCTATTTTTATACCTAATTTCATTAACTTTTCTAAGGCTAATATAACTGTAATACAGTTTTTTATTTGATGTTCTCCTAATAAGGATAAACATATATTATAAGTATCTTCTTTAGTTTTTAATTTAAAACTTTGCTGCCCCATATTTTTTTCTATGATTTCTATTTCTATATTTATTAAATTATCTTCTACTTTTATAAGATCACAATTTTTTTCCTTACACACCTTTTCTATATTTTTTTCTACTTCTTTCTTTTGTGGATACATTATAACAGGAGCTTTTTTTATTATTCCTGCTTTTTCATAAGTTATTTCTTCTAGGGTTTCACCTAAAATATTCATATGATCATAACTTATAGAAGTTATAATACTTAAAATAGGTTCTAAAACATTAGTAGAGTCTAACCGTCCCCCTAAACCTACTTCTATCACCGCAAAATCTACTTCTTTTAAACAAAAATAATAAAACATAGCAACAGTTATAATTTCAAATTCTGTAGGATTTCCATATCCCATATTTTCTACCTTTTCCACTATATTAGCTACCTTAGTTATAATATAACCTAAATCTTCCTTAGTTATATTATGGCCATTTATTTGTATTCTTTCTTCAAACTCCTCTATATAAGGGGATGTATACATTCCAACTTTATAGCCAGACTCTTTTAATACTGCAGAAATCATAGCTGTAGTAGATCCTTTTCCATTTGTACCTGCTATATGTATGCATCTTAACCTCTTATGAGGGTTTCCCAATAACTCTAAAAGCTTTTCTGTTCTCTCTAGGCCTAGATTACTACCAAACTTAGCCTTTGATTGTATATACTCTCTAGCTTCTTTATAATCCATATATAATCACTTCCTATGTATATCTTTTACGTAAATCATAACCCTTCTGTTACTTTTATATTATTTCTATTTAGCCTTAATAAATTACCTAATGACTACAGTATCTAATATTTCTTCTCATAAAATTGTAGATAAATTTTAATACATTTTTATATAATGTTTTCCTAGACTTCAATTGAAATTTTAAAACCCCAATTAACTCTAAAAATTTTGTTTATTACAATAAAATTATAATTTATTCTATTAAATATTAATAGAATAATCGTAAAAAATTCACTAAAACAAAATATATACTTTATATTTTTATATAATAAATACAGGAAAGTTACAAAAGTCTTCCCTGTATCTATTGTATTTCTGCTATTTTATCCGATAACTACCCGCTCTAATACTCCCGTCTTCTTCAAAGTGGGAGTAAAGAGCGGTTACGTCCCTGGATAACGATTTCTAAGCTTTAGAGGGAGTAAAAACTCCCTCTGAAGCCAAGAACTCTGTTTATATTATATTTATAATTTAATGCAAAACTTATTAATAAAATATAGAAATTTTAATGTAACTAATATTTAAACTAAATCTTATTTTAATGATTCTAAACTCTCACGCACAGACTTAAGCATTGCTTTATACTTTTCGCCCTTTTCTCTTTCCTCATTAACTACAGATTCTGGTGCTTTAGATACAAATTTTTCATTAGCCAATTTCTTTTCTACTCTATCTATTTCTTTTTCTAATTTTTCTTTTTCCTTATTTAGTCTTTCCAATTCTTTTTCTATATCTACTAATTCTAATAATGGTATAAATATTTCTGCACCTCTTGTAACTACAGATACATTTTTATCTGATGTTTCTTTATTTTCTAAGAAGCTAACTTCTGAAGCTGAAGCTAGTTTTTGAAAATAAACTTCTCCTTCTTTAAAGGATCTCTCTGCTTCTTTTTCTGTTAAGTAAATCATTAATTTAGCTTTTCTAGAAGGTGGAACGTTCATTTCTGTTCTAACATTTCTTATAGATTTAATAGCTTCTATAATATATTCCATATCCTTTTCTGATTTTTCATCTTTTAAAATTTCATCATATTCTGGCCATTTTGATATAACTATTGATTCATATTCTGTATATAAATGAGTATATATTTCTTCTGTTATAAATGGCATTATAGGATGTAATAATTGTAATGAAGTTTCTAATACTTTATGAAGTACATTGAAAGCTATTCCTTTTGACTGTTCATCTTCTCCATATAATACTGGCTTTACAAGTTCTATATACCAATCACAGAATTCACCCCATATAAAATCATAAATCTTTTGAGAAGCTATTCCAAGCTCAAATTTTTCTATATTTTCTGTAACCTCTTTAACTACTGTATTTAATCTTGATAATATCCATTTATCAGCTATAGTATAGTTTTTATTATCTTTATATTTATCCATTAAATCCTTATCTAAGTTCATAAGAACAAATCTAGATGCATTCCATATTTTATTAGCAAAATTTCTAGCAGCTTCTACTCTTTCAGGGTAATATCTTATATCATTTCCTGGAGCATTTCCTGTTACTAATGTAAATCTTAAAGCATCCGCACCATATTCATCTATTACTTCTATTGGATCTACACCATTTCCTAAAGACTTAGACATCTTCTTTCCTTCTGAATCTCTAACTATACCATGGATTAAAACTGTATCAAATGGAATATCATCCATACAATAAAGTCCTGAGAATACCATTCTAGCTACCCAGAAGAATATGATATCGTATCCTGTTACTAATGTATTATTAGGATAAAAATATTTTAAATCTGGTGTTTTATCTGGCCAACCTAAAGTTGAGAAAGGCCATAGCGCTGAACTAAACCAAGTATCTAAAACATCATTATCTTGCTGTAATTTCTCACTATTACATTTTGGACATTTTTTTGGTTCTTCAGTAACTACTATAACTTCACCACAATCTTTGCAATACCAAACAGGAATTCTGTGTCCCCACCATAATTGTCTTGATATGCACCAATCCTGAATATTCTCCATCCAGTTGAAATAAGTTTTATCAAATCTTTCTGGTACAAACTTAACCTTTTTATTTTTTACTACATCTATAGCTGGTTTTGCAAGTTCCTCCATTTTTACAAACCATTGTTTTGAAATTATAGGTTCTATTACCGTATTACATCTATCATGACAGCTTACATTATGATTATGCTCTTTTATTTTTACTAAGAAACCTTCATTTTTTAAATCTTCTACTATAGCCTTTCTGGCTTCATATCTATCCATTTCATGGTATCTAGTTTCTTTATAATTAATTCTTCCATCATCAAACATTACATTGATTTCTGGTAAGTTATGTCTTTTACCTACTTGATAATCATTAGGATCATGAGCTGGAGTTATTTTAACTGCTCCTGTACCAAATTCCATATCTACATAATCATCAGCAACTATTGGAATTTCTCTGTTAACTAGTGGCAACATAAGAGTTTTTCCTACTAAATGAGCATACCTTTCATCCTTTGGATTAACAGCTACTGCTGTATCTCCAAGCATTGTCTCTGGTCTTGTAGTAGCTATTTCTAAATATTCGTCACTACCTACTACTGGATATTTTACATGCCAGAAATGTCCCTCATGTTCACTATATTCTATTTCTGCATCAGATAATGCTGTTTTACATTTTGGACACCAGTTTGTTATTCTATTTCCTTGATAAATTAAACCTTCATTATATAATTTTACAAAGAAATGCTTTACTGCTTTATCTAGCTGTTCGTCCATAGTAAATCTTTCTCTTGTAAAATCTAATGAGCAACCTAATTTTTTAATTTGATTTCTTATTTTATTTCTATATTCATCTGTCCATTCCCATACTTTTTCAAGGAAAGCTTCTCTTCCTATTTCTTTTTTTACTATACCTTCTTTTAACAATTCATTTTCAACTTTAACTTCTGTAGCAATACTAGCATGGTCTTGTCCTGGTAACCATAAAGTACTATAGCCTTGCATTCTTTTTGTTCTCATTAGTATATCTTGAAGAGTATCATCTAATGCATGACCTAAATGAAGTTTTCCTGTTATATTTGGTGGCGGTAATACTATGGTATATGGTTTTTTATTTTCGTCTACCTCTGGTGTGAAATATGATTTTTCTTCCCAATTTTTATAAAGTCTTTCTTCAAACTCTTTAGGATCATAAGTTTTTGCCATTTCTCTTGTTTCTGACATTTAAATTCCTCCTCTTATAGTTATATATTTTTATACCTTGCCATTATATATTCATCAGCATATCTACCATTTTTGATAGCAGCATACTTTTTTGTCCCTTCAATTTCAAATCCAAATTTCTCATATAACTTTATAGCTTTTTCATTATCCGTAAACACTCCTAATTCTATTCTAACTAACATAAGCCAGTTATCTGCTAAATCAAGAATTTCACTCATAAGTTTTTTTCCTATACCATTTCCTTGGTAAGCCTTATGAACCATCATTCCTAGTGATGCTGTATGCTTTGTTCTAGGATTACTATTTATATTTAAACCAATTACTCCAACAACCTTATTTTTATCCTCTTCCTTTATTTCTGCAACAAGTAGATGGTCATTACTTCCTAAACTTTGTATAAATTCTTTAGATTGTTCAAGTCTTTCACTAATTCTGCCTAAAATATTTTCTCGTACTCCAATCATGCATCTTATTTCATTTATCTCTTTATAATCCTCAGGACTTACAGCTCTAATAATCATAGTCATACACTTACCTCCTTTTTATATTCTTATCTTAATCTATATTTTTACAGCATTAACTAAAAATAAAAAGAGGCCTTTCATCCTTAAAAGGACGAAAAACCTCGCGTTACCACCTTTTTTCCTGCAAAACTACAGGCTCTTGTATATTTAACGAATAAGAAATCCGTCTTTACTTACTAAACTCAGTAAAGAAGCTCCAAAGCTACCTTCAAGATAAATTATATATAGAAAACCTTTCAGCCTTTGAGTTTTCCTCTCTTAATACTTTTTATCTCTACTCCTCTTTTTCAAAGCTTTATTTTATAATTTAATTTTATTATTAATCATTTTACTTATTATATAACTGTTGCCAATATAATGTCAATAACATAATTTATAGTTTTTTTAATTTATCTACCTTTGATTTTTTATTAGTACAACAATGGTTAAAATAAAAATTAATACAAAACCACTAACAAAAAATTTTAAAACTTTAGATATCTGTAAATCTTCCATGAAAAACCTTAATATTTCTGCAAATAAATATCCAATATCTAAAGAAAGATGAACATCTTTTCTTAATTCTTGCTGATTCTTTATTTTATTACTATTACGTTAAAATCCTTAACACATGCATAAATAATTCATAAACATCATAAAACACTCTATAATTTTTCTCTTTTACTGCTTGAACATTCTCTGTATAACAAAAAATTAATATCTCACTTTCTGAATTTTTTTCAATTATATTTTTTATATCAATAGTAAAATTTTTAATAATTAATATCTTTATATCTACTTCCATATCCGTAAAACTATTTAAATTTTCAACCAATTCTTTCTGCAAATTAGTTTTATCTATACAAGATATTAAAATATCACAATTAAAGACACTATATACGTCTTTCAATACTGTACTATTTATACCTTCTATATTATTATAGTTCTCTCTGAACGAAATAATGCCCTCATGTTTACTGCTTTTTAATATAGAATCAACTATCGCAATAGCATAATACCCATTTGCCCTAAATAATTCACAGAAAAGCTTTGAGATAGTAGCACCATAGTATCCAGTAAAATCATAAAAAATCATTACTGGAACATCTACATTTTTTTGTATCTTATGGTTCCTCTTAATTAAATCAATTGAATTATTGTTATTAACTGATCTATTCCTTAGATATGTTTTTATTTCATTTATAGTTATATCTGGATATTTCTCAATAAGTTCATAAACTAAAGCAGTGACAACTGGAGTAGCATAGCTATTGCAGATTGAAGTAGTATAAACCATTCCGCTATTATCAATTATATTATGTTTTGCATTAGCTATTACTTCAATACCATCAAGAGAATAGGTATTATAAATATATTCAGACCTTTTTAGTGTTCCTGTTGTATCACATTTTACTCCTATAACATTATCAAAAGAAGCTGGACACGTGTATATTCTCTTATTATTATAAGCTGCTATTATAATCAACCCTTTTTTATAAGCATATTCCATACAGCTATATAATAATTTAAAATCTTGAAAATTTACCGTTCCTAAACTTAAGTTTATTAGTTTGATATTATTTTCAACACACCATTTAATGGCTTTAACAAGTTGATATCTTGTACCTTTGAAATTACTTAAAATCTTTATACTTCCTAATTCTGCATTAGGTAAATACTTTTTTATTATAGCTGCACAAGTAGACCCGTGATAGGTAAATTCATTATAACAATCTAAATTTTCCTTAATTTCCAAATCAGATGTAACTTCAATATCACTTTTTAGTTCCCCTAAATTACATAAATCACTATTTACTCCATCATCTATTATAATTATAGGGCTTTTAAAAGCCATTAAGAAATAATTGCCTCTTCCTGTCCTAACTGAATAATTATAATTTCTTTTATGTCATTAATTGTATTAAATCTATTTTCAACTACATACTCTTGTGGTATTGATATATTAAATATTTTTTCTACTTCCATGTATAAACATACTAAATCTATAGGTTCAAAGCAAAAAAAATCCCCTAACAAACTCCTTTCAAATAATTCCTCATTTATACTATTTAAATTTATATCAAAAATCCTATTAAATATATCATTTAATTTTCTCTGTACACTATTATTGTTAATCATACTATATCTTCCTTTCTATACTTTTAAATTCTCTTCATATCTCATTTGTTCTTAAAATATCATCATTGCAAAACGAAACTATCTCGATATATATTTAATTAATATATTTACATAGGTATAAATGGACCTAATAAAGTTAGAATCTATGTTCCAAATCCCTTAGTTCAATTTATCCAAAAGGTAAATGTAAGTTCATGGTGAAATGCCTTATTCATACCTTTATTTAAAAAAACAAACCAGGCTAATCCCAATTTCTTTTTTTAAATATCAATCTAAAAATCTGATGGTTTTATTAATTTCTAATTTAGTTTTATTAAGTTTAACTAGCAAATATTTTTTTATAATATCTTCTGAGTAGAATATAATAGATGTAACTCCTTTAATATTAAACATAATAAATATGGTTTTACCCAATAGATCAAATAAAAAAAATAAAAGTATAGTTTAACATAAAAATCTCTAGTGTATACCACCTTACTTTTTCTAGCTTTTTTAGTAATAAAGTTGACACATTTTTCTTTAATTATTTGCTATATATTGTAATAAATAACAAATGTACTTCAAAAGAAAAAATAATAAAAAGGATGTGTTAACCATCGCTAAAATAATTAAATTACAAGATGTTAAATATTATTCTTCCTTTAGAAATTTATATATTTATCGTTCCTATTCCCAAATGAGTATGAGTTACGTGTTTCTAAAATGGATACTAGAATATATCTTAACAATAAGCCTTGCATAGCAAACTAATTACTTAATTTTTTATTATTAATAAGTGATCTATAAAACTTCGTATTCTTCACATGCAAGTTTATTAACTAAATGTTCTGTGATTTTTGACCCTTCATTTTCATTCATAATATTAAATATTGGTATACTATTGTTTAGTTCCTTTATTTTATTGTTTACTAAATCTAAAGTAACATCTATATATTTTGCTTCAGTATTAATCTCAAAATAATTCCAATCAATCATTGAATTAACATAATTAAAACAACTTATATCACAAGCAAATTTGTATTTTACTTCTTGAGCTATTTTTTCAAAGAATGATGGCAAGTAATTTTCGTATAGTACACTAAGAATTGATGCGTCTGGTTTAACAGCTTGTGATACCTCAAAAGCTAAAACTCCAAAATCATAAGTAGCTTTATTATTGATTCTCATTATAGTACCAGGTATACCTATTATTATTACATCTGGATTTTCTTGAGTCTCAATATTCTTAATAAAATTATTAAATAGCTTGATCTTTTCAGTCTCTGAATACATATTACTATACATGAACTCAGGAAAGGAATGAAAATTAAACATTTCACAATAGTTCCTTGAACCTACTTGACTTACCTTATAGCCCATATTAAATAAATTTTCTCTCACAGAAAGTTGAATTTCAAATTTGTGAGCATTTTCTCCTACTCCCATCACAAATATTACTGGTGTTTTGATTTCTTGAATTTCTAGTTTATCAACATAACTACATATTTCATAATTTTTATTTAAAGGATACTGAATAAAAATATTACCTTTATATTTACACACTTCCTCTATCATTTCAATTTCTTTAATATCAAATTTTGCTGTAGAAATAATTTTTTTATTTTTTTCTGCAGCCTGTACAACTTTAGGGTATATACTTTCCTTAAAATCTAACTTTAAAGCTGAATTACTTAATATTAAAGTATCACAATTATTAAGCGTACTTTCGAAATTATTATTTACAATAATATTTAAATCTTGTCCTCCATCAGCATAGCTAGCATCCTTCTCACTAAGTCCCCATCCATTAGGAGCTACAACTTCAACAATTTCATAATCACATATACTTTGATGTCTTATTATTGTAGAAAATTCTCTATCATAAGGATATATCAATGCCTTTTCTTTATTATTCATTTAATAAGCCTCCATATTACACATATTATATATTACTCTATTATTCTTCAAATTTATATCCAAATTCCATCATTGTACAATATACTTTAAACATTTCTTCTGTATTTCTTTTAACATCATTGCAGAACTTAGCTCTTTTGACTCCACTTAATTCATTCATATCATCAGCAAACGCAGCACATAAATAACAATATCTAAATGCCCAACAATTTTTGCACTTTTGCTTGGTCATTTCTCCTACATTGATTAATTTCTTGATTTTTTCTATCTCAAAGCCAGTATTAACATTACCTATATTCATGGCTTCTGATTCTTCATTTACTCTCTCACAAGGGCAAAACTTTCCATCCACAGTCATAAATAGCCTATTTAATCCAGGAATACAAGGACCTCCTGGATGCATTTTTTTAGGGACTTTTTCGTTAGCTTCTCTCTTTACATTTAAAGTATGGTTTATATGTTCAAATTGACTCAATAGAAGCTTTGAAATATATTTTTCATCTAGTTTTCCAAGTTTATGTAATAAAATCTTAAATCTTTCGTATTTCTCATCTTGGATAAAGTCTTCTGAAATTGCTTTCTCCTCTAATGCTCCTAACGTACTTACATCAGTTGCATTTACACGAGAATCTTTTACTGTATCATAATTTGCAAAAAAGTTATTTATGCAACTAAAATCGTTCTGTCCGTCCATAACAATATTAAACCCTACATTTTTCTCAACATATTCAGGAAATTTTACTTTTATTTTATTTACATTATTCATTATTTTATCAAATGAACCCATTCCGTTTGAAAACACTCTATTCTTATCATGTATCTCCTTTGGTCCATCCATGCTAATGAGTAACGAAACTTCATTATCTTTCATAAATTTTATAATTTCATCAGTAAGTAAAGTACCATTTATAGTCATATTGAATGTTATTTTTTTACCTTCTCCTTTCTCCTTTGCATAAGCTACACATTCTTTTATAAAATTAAATCTTAAAAGTGGTTCTCCTCCATAAAATGCAAAATTAACTGTAGGTGAATTTTTAGAATGATTTATTATAAAATCTATACCTTTTTTTGCTGTATCTATACTCATTATCTTGTGTGAGTGAGATCTATTCAAATAGCTACCAGAATATACACAATAACTGCATCTTAAATTGCATTCTTGTGTAATTTGGAGTGTAAGAGTATTTAGCGAATTGTCTAAAATACTTTCTAATGCATCAGTTAATGAATGTTCTATTTCTTCAGCTCTATTAGATGATAAATATCCTTTTTCTTTTAAGTTTAGGATAACGCTATCGTCTTTTAAAGCTTCTAGATCACCATTATAGTTCTCTAAAGCACTATATGTTTCTTTAGGTACCTTTAAAAATAAATTAGTATTTACATCATATATATAGCAACAATTTCTTGTTTTGAACAAATGAAAAAAAGCATTTTGTTTCATAAATTTTCTCCTTAAATCAATTTAATTAATATAAACGACATAAAGGATAATCTTTATGTCGTTTAATTTTAATAATAAAGCTTTAAACTTTAATCATGACTATCATAACTGTTTCCACGAGATACATATCTTGCATTATCCGCATTACTACCTCTGCTCCTGTTAACTGAGCTTTGAGGATCATAACCACAGGAACATGTACAATTAGCATAGCAATAACCACAATTACATGAGTATGCTTCCAATGAAACTAATTCACTTTTTTTATTTTTTACTAATTTTTTCATAGATTCCACCCCTTTTTTGTTTTTTCTTATCAAAAATCCGCGAAATTTTTTCAAAGAAACGTTATATATGAATCTCTTTTCCTTAAGGTTAAAATAGAGATTAAACAAATTGTTAAAATTTTACTTTACATATTGTAATAAAACACCTTTTTTGTATAATTCATCGTAATTACCTATATCTTGTATTACACCATTCTCTAATACTAAGATTTTATCTACATATTTTAATATTTTAGGTTTATGGCTTATAATTAGCACAATTTCTTCTTTAAGTTCATTTATCAATACCTCATTTATTTTATTTTCAGATTCAATATCCACATTTGAAGTACCTTCGTCAAATAATATTATTTTTGAATTTGAAACTAAAGCTCTAGCTAGAGCTAGTTTTTGTCTTTCTCCTCCTGAAAGACGTACTCCATTACTTCCTACTTTAGTATTAATTTTTTCATCAAGTTTTTCTATAAATTCACCTGCTCCACTTCTAGCAATAGCATTATGAATATTACTTTCTTTTATATTAGGCTTAAAGCCTATGTTTTCTTTTATAGTTTTATTGAATAAATAAAAATCTTGGCTTACTATAGAAAACAAGCTTCTATAATTAGATAGCTTTATATCATTTATATTTATACCATTTATAGATATTTCACCTTTATTAGGTTCATAAAGCCTTAACAATAAATTAAACAAAGTAGATTTTCCTGCTCCATTCATCCCAACTATTGCTACTTTTTCACCAGATTTTATATTAAAATTTATATTACTCAAGTTCCATCTATCCTCATTGTATGAAAAGTATATACTCTTAAAACATATATTCCTTATTTGTAAATCTCTTTCTAATTTTAAATTTCCTAGTGTTTCGTCAGATTCCATATCCATAAATTCAAAAAATCTTTTGGCAGACGGAATTATATTTATATAGTTGTATTTTATTCCTGCTATTGTGGATATAGGTGATGTTACTTTAACACTATATGTTATAAAGGCAAGTAGTCCTCCTATAGACAAGTTTCCCGAAAAGGTCAAGCAAGCTCCTAAAATATAGAGAATATTTGTAATGAAAGCCAATGTTATGCTTTCTAAGCAATAATTAATTTTATCTTGATAAAAAAATTTTGTATTGTTTATAATTAGAGCTCTTTGTTTCTTTATGAATTCACCAATTTTTACCCTTCCAATTCCGAGTAATTTAATTTCTTTTACTCCATTTAATGTATCTCCATACCAAGACCAGTATTCTTCAGCATTAATCATGTATTTCTCATAATTTTTTTTCCTTTTTTTAGAAAGAATTTCAATAGTAAAATATCTTAACGGAACTATTGAAATGACAACAATAGTTAGTTTCCAACTTATCATTAAAAGTCCTAGAATACCCCCTATTATGTTAAAAATTTGCATAATTACATATAATGATTCCCTATTTAACAAACTACATATATTTTTTACATCCATGGATATATTACCCATTAGTTGAGTATTATTAATTTTATTTAAATCTGATAATTTAAGAACCATAGTCTTTTTAAATGTTTTCAAAGTTAATTCATATGGAACCATTGTACTTAAATAAGCTTCATATTTTACTTCTAAAAGCTCAATAGCTTGTCCTGCTATAGTTATAAAAAAAATTTCTAATGAATATTTTATAACATTAGATAAATTATTATTTAATAATCCATAATCCATTAAAGCCATACTAATTAGTGGTATTGTAAAACTAATTCCAACAGAAATAAGCATACAAGCTAGTACACAAATTATTTTCTTAGAATAAGGTTTAAATAATTTTATAACTCTTTTTAATATTTTTTTATCTTCTTTAGAAATAAAATATACTTTTTCATCTTTAGTATTCCTAAATAAATCGTGCTTTCTCTTCCAAGAGTCTTTTAAGTAACAATATAACATTTCATGCTCCTATATTTTTGGTATTATTTATATAAAAATATCCACTTATACCAAAAACTGTTATTAACTATTTATGTATAATATATAATATTATACAATAAATGTCAACGAAATTTTGTAATATTCTTAATTTTACGAAAGCATATTGCATTTTATAATTGATAATCCATTAAGTTAATATTTCAACATACCATTTCTATACTCGCTTTAGAATTTCAAAGTAGCTAATTGTATTAATAAAATTACAAATATTCATCTAATCTAAATAGAATAATATAACTATCATGAAACTTTACTATCATTATTTCAGCTAGAATTCCTATCAAATATGTAGATTTCTCTATCTGATTTTTTAAGTGTTTTGCTAATTATATCCGATAGGCTTGAATTCTTAGATAAAATTATGAAAAGGATTATTTACAAAAAACAAAAACTAGCCCTTAAGACCAGTTTTGATTTTATTTAGATAAATTTAATACTAAACAGTTCTCTAAAATAAATCTTTTATTTTAGCTATTAGTATATATTTTGATACTCTCTTTTCATTTATTAATTTCTATACATCTACTAAATTATGTTGACCTTCCTCTATAAGGGACCCTACAAGTTCGGGTAAATTGTCACTTAACTTCTCCATCAGAAATAGTAATTATCCTATCTGCTTTGGAAGCTATTTCTAAATCATGAGTTACAATCACTAATGTTTGTTTATACTTTTTACAAGATAATTTTAGTAACTCCATTACCTCTTTTGAATTTTTTTTATCAAGATTTCCTGTAGGCTCATCTGCAAATATAATTGAAGGCTTGTTTATTAATGCCCTTGCTATAGCAGCGCGCTGTTGTTGCCCTCCAGAGAGCTGTGATGGAAGATGATCTCTTCTACCTCTTAAATCTAATATATCTAATAACTCATTTAGATAATCTTTATCTATTTTTTCATGATCTAATAGTATAGGAAGTTGTATATTTTCCTCTAATGTTAGCACAGGAATTAAATTAAAAAACTGAAAAACAAATCCTATTTTTTTTCTTCTAAAAGCTGCAAGACTATCTACATCTAAATCATATATATCTTGATTATCAATAATTATATTACCTCCTGTAGGCTTGTCCAAGCCAGCCATAGCATGAAGAAGAGTGCTCTTTCCCGATCCACTAGCCCCTACTATAGCCACAAATTCTCCCTGATTAATGGTTAAATTTATGTTTTTTATAGCATCTACCTTTGTTTCTCCACTTCCATATGTTCTATAAAGCTTATTTATACTTAACATTAGACTTCCTCCTAATCAATATTCTTTATATTGCAATAGATTTTCCTTTTTAATTTTCCTTAATGGAAAATATATTGCTAATATTCCAACCACCATAAAAAACACTATACTTATCAAAGTTTCCTTAAAAGGATACACATATGCTATATCATGTCCTGTTCTAAACATCATATTAATCAGTATAGAATTTATCCATCCGATAACATTTCCATATATTATTCCTATAATCGAATATAACATCCCTTCCAGATACATTATTTTCTTTTACTTTTTTCTAGAAGCACCAACAACGCTTAGAAGTGCTAGTTCCTTACTTCTTAAGATTACATTAGTATTTACTATATTAAATACATTTGCCATACTTATAATAGATATAAAAGCTATAACACTAAAATAAAAGAGCTTACTAAATTTAATATATTTTTCATTTTTTTCACTAAAAATACTAAATCCTTGAATTTTTCCATCATCGCTACACGCTCTCCATTGCTCCAATAGTTCCTCCCCAATATCTCCTCTTTCCTTATTACTTACATTATCCTTATAACTTACAACCAAGCCTTTAAGTTCTGGAAGCTTCAATCTATCTAATTCTCGTTTTTTTCTAATATTACTCTTATTATCTTTTGATACACTAACATATTTCTTTTCAATTAGCTCATTATAAACTTCCTTAGGAATATATATTATTGGAGACATATTATAAAAATTCTCCTTATCAAATAGAATTACTCTAACTACACCCAAAATCTTTACTTTCATAGCTCCTTTTATTGTATTACTATTACTTTCAAATTTACTATTATACATTAAATTTGATGTATCAATTAGTATTTCATCCCCTACTTTCAAAGTTGCAATATTTTTCTTCTTATATTTGTTCTCTCCTAAATTTTCCATATCATTTTCATAACTTATTTGAGTAATATAAACACCTTTTTCTTTTTTCATTTTTTCCTTATCATTAAATTTTTTCAAAAGATATGGGGAAAGCTGATCAATAGTGTCTAAATCAATTGGTATTATTTCAGATTTTATATTAGTATATTTGTTACCTTCAATACTTATTGATTCACCTTTTACCAATGCTTTTTTTTCAGGTATAAAAGTATAAGACTTTATTCCCTGATATATTCTATATACATCTTTTACACCATGTATTTTTTTAACGTTTTCTACAACTCTCTTTATTTGTTCACTATTATTTTTTATCATTTCTTTATTGGTTTCATCATTATATATATTAATGAAATAATGATTATGCCCAGCCATAAAATTATCTATTGGCAAAGCTTCATAAGGAAGCTGTTCTATGTTGGAAACTAAACTACTAAATGTAATAAAAAGAGTTATTGAAAGCACAACTGAAATCACTGTTGTTCTAAATCTTCCCTTATTGGTTCTTATATTTCTATTTGCAATAACTTCCTCAATGCTAAAAAACTTATTAATTAATTTTTTATTTCTTGTATTTACTTTTTTCAAATCACAACTCCTATTAGTAAAACAATCTAGTGGTGATATTTTTTTTACTTTTCCTAGTATAGAAATTACTGATAAATATAATGTGATAATCGTAATTATGATTGTCCCCAAAATGCTATATAAAGAATAATATATTTTTATAGTGATTGATTTACTTAAAATCAAACTATTAAATGCTCTAAATAACACTGAACCTGCTGCCATTCCTGCTAAAAGTCCTATAGGCAAAGATATTGCCCCAATTATAAAAACTTCTTTTAAAATAATTTTTTTTATCTGCTTATTAGTTCCACCTATAGCCTTTATTAATCCATATTCCTTCATTCTCTCTACTGTAGATATATTAAGTGAATTGTATATAAATATTAATGTTGCAATCATTACAATAATAGCTACCATAAAAAAGGTGATATAATCTATAATATCACTTTTAGTCCTACCTTCTCCCATTGCGGTTAAGAGTGCTTCATTCTTTACAATTTTGTCAGCATCTATATTAAATTCTTTAGCTAAATTATCTATTTTTATTATTTAAATTTTTTTACTTCCTTTAATTTCACATATACCTCTACATTATCAATCACTCCATTATCATTGATGGCGTATGCATCAAATGTCTTCAAAAAAGCTTTATTAGTAAATTGTGAAAAACCTACAATGGTATAATCTATATTTCTATTATTATCTAATTTAACAGTTATTTTGTCTCCAATTTTTTTATCTTCTCTTTCTTTTAAATCTAAGCTTAGTATTATTTCATTTGCTTTCCTTGGAAATCTTCCCTCTTTTAGTCTTACCCCTAATAAACTAAACCCTTCCTCATCTATTTCATTGATTACTAATGCTTTTTCTCCTAATTGCACACTTCCAAGCTTTCTACAGAAGCTTGTCTTCTCCACCGCCGAGTGTCCCTTAATCTTTGAAAATTTTTCTTTTTGGTGCAATTCAAATTTAAAATGATAATCTCCATCTTCTCTTATCATATTAATAATATTTTGCTGAGAAGAATACATCATGTGCCCTGTACCACTTATAAACATAGTAGCTAATATTATTGCAATTATATTAACAATGCTTCTTCTTTTATTCTGCCTAAAGTATTTACTAGATATTTCCACGTAACCTTTCATATTATCTTCCCCCCTACCTTCCTAGACATTGAGAAAATTTTGAAATATTTTTATGCTAATTTTTTTATTTTAAACGTTCTTATCCAAGTAACTTTCCCCTTTAAGTTTTCATATAAAGTATTAATTTACAATATAAAAATCATCAATAATTAACAATATATATTCTTTTTCATCATCGATTGTAAAAATCCTCTTTTTTTACTTTTTTATCCTTTATTTATAAATGTAATATTATTTGGTTTGGAGAAATATTCAATTCTTTGCGTGATTTCCTGTTAAATATTCTATTCATGTGATAATTAGGCTTTTGTAACAATATCAATTTTATTCATCATTTTTCAGCATTATATCTATATAAAAATAAAAGTATTTAACATAATTAATATTAACTTCATACTATGAACTAATATGAAATTTATCTTGGAGGATTCTTATGAAAACAAAAAAGTTAACTTTACTTTCATTAGTTACTATACTTATTTTTTTATTAACTTTATTTACTGGATGCAATAATAAAAAAGAAGAAACTGAAAATTTAACAAAAGTAAAATTAAACGAAGTAGTTCGCTCTGTTTTTTATGCTCCTATGTATGTAGCTATAAACGAAGGTATTTTTAAAGAAGAAGGTATAGAAATAGACCTTTCAACTGGACAAGGTGCTGATAAAACCCTTTCATAAACACAAGTAAATAAAAAGTAGCTAAAAATTTAGCTACTTTTTTAAATTTGTTCTTATTTTGTTTTCAGCATTAATTATAATTTCTGCTATATCATCTTCAGTTGTGTCCTTACAATCTAATTCTTCAAACAATCTAAGAACGTTAATTAAAAGATCCTTTTTTGGCATAATATTCCCTCCAGTTTTAACATGGCTAAAGCTAAAAAATAAGGAGGAATTTATGTTATTAAAGGAATTAAATTTATTATAACTTTTTTACATATTTTATACAATATATTTTTCCAATACATTGTATCCCTCCTTATAAAATTTTGAGTTCTATCATGGTAAATCACCTATTGTATATTTGTCTTCTTTCAATTGTATTATAACTCAAAAAATATTCATGGTATGAATATCGTTCGTCTTTTTACCACAATTTTCTTGTTTATTATTGTAATTTTTTATCGTAAAATTAAAAAAAATAGGATATTGTGCGAGGTGGTACATATGATAAAGATTTTTCGAGAGCATAAAGGAATTAGGCAAGAAGATTTAGCGAGCAGATTGGGTATAACACAACCTTATTTAAGTAAATTGGAAAATAACTCTATATATGGGATTAATGTTAATGTAGATCTTATAGAAAGTTTAGCAATGGAACTTAATATTTGTCCAATAGCTGTATTTTTGTATTTTCTCAATGTAAAGATTTCATGTCCTTTTTATTTAAAAAAGACAGAATAACTGGAATTTAAATGAATGCCTCTTTACCTGCTATAAACTTATTTTATAGAAGTTTATAGGAGGGATTATTTTTGTTTGGGGATAGATTAAAAGAGTTAAGAGAAGAAAAGGAACTTACGCAAGAGGAATTAGGAAAACTACTTAGCGTATCTAGGCAGACAGTATCCGGTTATGAAGCAGAAGTTATAGAACCTAACATAAATAATTTAGTAAGATTATCAGATATATTTAATGTAAGTTTAGATTATTTATTGGGTAGAACAAAAGAAAGATATAATTTAAATTTAGAAAATAAAAAAAATAAAGAACTATTATTAGATCTAATAAAAGTAATAGATAAATATAAAAAATAAGCCTTGGTATTATCCAAGACTTATTTTTGCTTTTCTATAACATTACCACTAATTTGTGGAGCACCTGTTTCACTTTTATTTTCATTTAGCTTACCATAAACTTTTACTTTGTCTCCTTCTTTTACTTCTGCCTTTCCAAAGTTTTCAATATCATACATACCATATCCTTCACCCTCTTTTGTTTTTACGGTAAACTTAGGTAATACTGAATTAGTATTATCAATAAATGTTACTTCTCCTTCTATATAATATGATTTCCCTTTTAACTCTTTTTCATGTCCATTAATTTTTACAAAATCAGCCTTTACAGCAGAATCTTTTATTTTTTTATTTAATTCTTCTTGGCTTTCTTCTTTCATAGATTCTTTTTTAATTTGCTCTTGTTTTGGTTTATCATTATTTTTGTTTTCTTCATTGTTTGTTTGTGTAGACCCACAAGCAACTAATCCTAAGGTTAAAATTCCTGATATTAATATAGATATTAGTTTTTTCATGTACTAATCCCCCTCTGTTAAGCAATATAGTTTAATTATAACAAAAATGTAATATTTGTAAATAAAATATCAAATTTTATAATTCTCTTTGATATTCTACTAGTTCTAGTTCTTTAAGTTCCCTTTGGGCATTTTTTAAAGATTCCATTAATTCTTCATTAGGTTTAATCTCTATCCACTGCCCTATAATTTTAAGTTTCAATTCATACTCTTCTTTCTTTGTCATCAGGTTCACCTCTTTGTAAATTTTTATCTACACTATTTATTATTTGTGCAATGCTCTGCTGGGATATTTTATATATTTCTGACATAGCTTTAATAGTTTCTTTAAAAACTTCTTTATCCTGCTTTATATCCTTAAGACTATTAGATAATTCTTGTTTTTCTAACGTTGTTAATTTAGCATAATCTTTATATTTATTTAGAGTACTTTGTACATTTTCTAATTGTTCTTTTAATGCAATTGATTGTTTACTTTTTTTAATAACTTCTAAAGCATTATAACTATCTAATCCACTATTTAATATTCTATAAAAATTAGATATTTTTACATGGTGTGCTTTAGATCCTCTTTGTCCTCTATTAAGTTCTTTAAATTGTTGTTTTATAAAACTGCTGTATTTATCCTGCCATTTACTAAGTTTTTTCTTTCCATCGAAATAACGTGAATTAGCCAGTACATATCTTTTTTTCTTTTCTTCCCAAAAGCGAGGAACTACTAAGGCACTTATATGCCAGGTAGTTTCATCCCGATGCAAAGTAGCATAAACACAATTTTCACCGAAATGTCTTTCTAAAAATTTAATGTTAGTGTTAACCCATTTTTGCTTTTCTTCTATAGATAAGTCTTTAAAAAATTTAGGTGATGCAGTTAATAATAAATCCCTAGCTATAACGCCATTTTTTCTAAGCTTAATACCTTCTATATATTCTTTTACATCTGCCATTATAAAATTGCTCCCTAGAAGCCTTACATTAGATATATTAGGATTTGCGTTCGGAGTTTGTTGTTCTCTTTCCATATGTCTTTGGTACCCAGCTATAGCTCCTACTGTTTTATATTTCTTTTCTCCGACCCTAAATATTGCATATAGTTGACCTGTTATTTCCATATCTCTTCAACCAGCCTATTAGTACTGCTATTATCTAATTTTTTAATTCCTTCTAATATTAAATTTTCTTCCTGTTCTTTTATTTTATGTTCTACTTTCAATTTAATATTTTCTTTAAATAAATTTATATATTTTTCTTCATCTGATTTATTTTTAATAATGTTATTTGTTGGCAAATTTATTTTTAGAGGTGTTTCTTTAATTTTAGAATTGTATTTTTCTTGTGTATAATAGATATTCTTTTTATCTAAGATAGGTTGTTTATTATGCATTACAATTAGCATATCATCTTCATTTAAGCATCTAATATCCTCTTTATTAAATAATTTTTTAGTAGTATAAGAATAGGATTTAGTAGTGTTATCTTTCGTAATACTGGTATTACATACTTGTATCTGTGTGTTACCACAAAGTTGACTTATATAATCTAATGTTTTTAAATCAGATAATCCACTAAAGGCTATTTTAGTTTTTAAATTATTAAGGATAGATAAAGCATTATCTTTACCATATATTTGTTCTAGCTGACTAATACTCTGTAAGCATATATTTAAAGATATTTCTCTGCTACGTACTGTAGCACAATTCACACTCATGTTATTAAGCATCCCTAGATTTGCAAATTCATCTAGGAAAAAATAAACAGGTAGAGAGTTCTTATTATATGAATCTAAAACTTTATCAAATAGCTGACTAAAGAAACTAGCCATTACAGGGCTAACGTAGCTAGATCTGCGTTCTTCTGATATAATATATATACAAGTAGATTTTTTTCTTAAATGTGCAGGGTTGAAGGTGCTGGTACCACTTAAAACCTTGCATATTTTTTTATCTCCAAATATTTTTAATGCAGTTGTCAAAGTAATTTTTATACTACCTATGGTTCTATCTGCATCTCCAACACTATTAAATATATCCCATTGTGTTCTACAGTCCTCGGTACTATTAGAAAATAAAGTATCTAATTCTTGTAAGCTTTTTTCTATTATAAGTCTAAATGCATTTTCTATCGTAGATACAGGTAATCCTTGTGCTTTACAGTATAATAATGCTGCACTAAATAATGGTGTAGCCATATTGTCCCATTCTGTTCCTCCTGTCTTTTTACCTGTTTGCAGTTCTATTGCTAGACTTCCATTTGTAATTAAAGTTGATGCTAATTGTAGAACTTCTGTTGTATCTTTACATTGCTCTAGTAAATTATATTTACAACTTATAGAAGGTTCCAAAGGTGCAAATACAACTATATCTCTTCCACAAATATTCTTTTGGAACCAACTAGTTTTCTCGTAGAGTTCTCCTTTAGGATCATAGGCTACAATACTTCCTTTTAAGTTAGGATTTAGTAGGTTAGGTATAAAAAATGATGTTGTTTTCCCTCCACCTGTTGGAGCTATAATTACTGTGCCTTCAAATGCAATTTTTTCTTCTAATTTAATGTTTTTAGAAAGTTGTAAATAGTCTCCTAAAATATTTTCCAGGTCTTTCTTAGTAAATAATTTTCCATTGGCTAAATCATCTATTTTATTTTTCTTATTCTTTAGTTTTACTCCAAATAGTTCTGCTGCTATAGTACTTCCTCCAATTAACGCGGTACTAGTTAATAAAGATAACATATATATTCCTCCTTTTTAATAATTAGCCACGAGAATGAATAATGGTGAATACCTTTATTCATTCTGTGGAATAGGGGTTCTAAGGGTCTCCCTAGCGAACGGGGTTTTTGATAAAAAACCGTAGTGAGTTACGATTTGCAAAATTTTAAAAAATTTAAAAATTAATATTTAATAACATGAAGTATTAAACTACGGCAGGTTGCAGTATAAATAAAATCTGAACTCAAAACAAAGTAGAAAAACCATAAGCAAAGTGTGCGTAGCACTACGGTTAGAACTGTTCCGTCATAAAAAATAAAGGTTTCCACCATTTATTCTTTATGGCGGCTGATTTCTCTTGTTTAATATATCCTATGCATATAATGCGAAAATGTTTACTTTAAAATTAAAATTCGCATTAAATCCGAAAGTAAAATAATAAAAAAGAGATATGATTATTCTAAATACCATATCTCTTTTACATCTTTATTTAATTTTTCTGACATTTTTAAAGCTTTATCTAAAGTTGGTTTACTTCTACCTCTTTCCCAACTAGAATAATTTTTTATATCTACATTTAAAAATTTGGCAAATTCTCCAGGAGCCATTAAATATTCCTGCATTCAATTTTTTTTAAATTATTTTTTACGACCATATAATACACCTCTTTCTTATATTATATGCTCTATTCTATTTTAATTTACTAATTTCCTTTATATGTTTAAAAATTATATTAATGTTAAAAATCTAAATAGGTGATGATATGAAGTGTAAAATAAGAATAGATTTATGTATAACAATAACTTTTATAATGCTGCTATGTATATGCATACCTATATTGTTCAAAAAATAAAAAAGAAGTAGTTCCAATTAAGAAATTACTTCTTTTTATATTTATTCTTCCATATTATCAATATAGCTATTTTCTATGCTTTCTTCATATTCTTTTAATGTACTAATCATAGCAGATATAGCCTCTACACCTATATCTACTCCGTTAATGCCATCTATAATTTTATCTCCTAGCACAAACTTAACACGTTTAGTTTTAGCAAATTCTATTATCTTTTCTAATCCTTTATGGCTACGTGTTATTCTATTAATATCTTTAGAGAATATTGTATCCCCCTCTTGTATACTATCTAGTAATTTGTTCAGCTCTGCTCCATTTTCAAGTGCACTTCCAATGTCTATATAAATATCCTTTTCGTTAACCCCTTTGCTTTTTATCCATCCAATTTGATTCTCTATACTTTTTTTATTATCATTAGCAGTTCTACAATATCCATATATCATACAATCAACTCCTGTTATCTTTTTTATAATATAATTTTATCAAATTTAATTTATTTTTACCAATTTTATTACTGTATTGTTCTTTAAATTAGATAAATAAAGAAATTTTTCTCCTTCTTTAACTTTGTCTAAAGATACCCACACAGGTTTATTCTTATCTAAACAATACATATAATATCCGTTTTCTCTTCCATTGTCTTCTGCTGGTGCAACCGCATTGGCTACACCAACAAATCTAGTTGAAGCTCCTATTAGCAAGCCTGTTAATAAACTTATAACCACCTTTTTCATTTTTTAATCCCCCTATTCTCGCTTTAACAATTCTTCTCTTTCTTTTAATAGATTCCTAAGTTCTTCTATGTCCTCTAGTGTTGCTTTATTCCTGATAAAGCTTCTAGCACTGCTACGACTTTTCAAATAACTAGCATACTCTCTATTTTTATTTTCCCAGTTTTGATTGGCTATTGTCTGTTTAGATTTTCCCATTTGAAAACCTCCTACATAACTATTTTAAATATCAAGCATACTAATAGAGCTATAATAATTAATTTAATGGCTATCTTTAGTATTAATTTAAATAATATTTTTAAATCTTTACTCATATTTACTAAGGTGGTATTATAAGAGTAAGGGAGGAGTTTTCCTCCCCTGTGTTCATAACAAATCATATAGCTGTTTCAGTAGCATTATTATGATTGTTATTTTTACTAATAGCTTGATGACTATTCCCAGTAGTTTATCAAGCTTTTTTAGTTTTCTTATCCATTTGACCACCTTTTTCTCTCACCTCCTTACAATTATAATTATACTACGTGTAGTATGAGAAGTCAATACCTTTTATTTAAATATTTATATAAATTATAATAATTTTTCCAATAAAAAAAGAGGTACTCCCATTACAGAAGTACCTTTAAAATTAATATCTTATACATTTAGCATAAATATTTTCCCATAAGAAAAAAACCACCATTAATTAATGGTGGTTTAAAATCGTAATTTGACAGTACCTGGGGAATGTGTGTATTTACAATACACTTAAGCGATAACATTAGCTACAATTTCCCTTGGCAGGGCTTTTAACTGTTAATTACATTATAATATATGTCTTACAAATGTGTCAATACTTTTTTCTCAATTTCTTTGCAATGAATTTCTTTTGCAAAATCTTTATATGGAAATTTAGATAAATAATCTATTTCTATACTATTACCGTATTTCTGAATTCCATAATTATATCTAGCCCAACACAAGCCCGCTATAAAATCGCTAATCATAACACCATAATTCACCTTAGAATCAGCTTCTTTAATATTAAAATTACAATTAAATTTGTTATGTTTTCTTTCAATTTTTAGTTTTTTAAGTAAATATACCTGTAAATTATTATTTGCTTCTATCTTCATACTTCTATTATCATATATAATTTTTAATTCTTTAAAGTCATACCCTTTAGCATACTTCCTTATATCAAATACATACTTCACCAATAAATATACAAGATAGTTATAATAATCATTATATTTATGATTAGTTAACCTCGTGCAATTGAACTTGTCTACAACTATAGATACATAAGTACCTTTGAGTTTTTGAAAATTTTCATAAACATAGTTTTTGCCATCTACATTAAGATTTGAAAATTTAACCTCATTTTTATTATTTTTCCTTGCATTAATATTAAAATATTTTTCTCTATTTTTTTGCACATTTGATACTATTTTTTTCATCTTGTATGCATGATTCTTATTTCCTTTTTCTATTAAGTACCCACCAATGCAAAAATATCTTTCCCCATTGTTTTTACTTATGTTACCTGACTCATCTATAAAAAGTGTATAGCTCACAATATGCCTCCTGTTAAATTACGATTTTTCTACTAATTATTACAATTATATCACCAACTATATCCCTTACTCAAGGAATTTATCCAGAATTATTTTTTATTCACATTTTTTTCAATTTGTTTTCTATAAAATTATATAAATTAACTTAATTTTTAATATCTTATATATTTAGCATATACATATCCACCCTGTTTAGGATAGTATATATGCATCCAATCTCCTTCTTTTCTATATAATTGGACTTTTGATCCATTAGATAAAGTACCTAGTATTTTGGAGCTTGTAGATTTATCTGCTCTTACATTTACTCCACTAGGTGTATTTATAACTCCTGTTTTACCATCTAGGTTTGTCCCACTTGAACTACCATTACTACTACCTTGAATGCTTACATAATTCTTATAAATATAACATCTATTATATCCGCTGTATAAACTATAGCAATGATACCAGTCCCCTTCTAGTCTATATAATTTAACCTTATCGCCTTTGTTAACAGAACCTAAAATTTTTCCATTAGGATCTAATCTCACATTTACGCCGCTGCCTGTTATAATACCTACTTTGTCCCTAACATTATCATTTACAACTGGACCAGGATTATTAGAGCTGCCACCATTTAAAACAGCGTTTTTTATTTCTGCTAAAGGGTATTTTGTTCCAGGACAATTAGAGCTACCAACTTCCCTATGACCGTATATTTTATTGATTCCATATTTATTACATAGATATTTGCATAACTCTATAATTGCATTCTTTTGAGCCTGAGGCATATCCTCGCTCATGTAACTACCTTCGGCACAAATCCCTAACGTATTGGTGTTATGACCAGCTACATGAGCACCTATAGCGCTATCAGGTCTACCTTTCCATATCTCCCCGTTTTTCCTTACGAAATAGTGATAACCAATTCCTGCCCAACCGTTTCCTTTATGCCATGAATGTACATCTAATACACTACATACACTCGCTTCAGCATGATGTAAATCTAGTTCTTGAGGGTTATTCCCGTAAGACATACTGCCAAAACTTAAATTTGCATTTCTTATATTCATATAAATACCTCCCGTATCTTTATCATGATTTCTATACAACTAATAATGAGAATTTAAAAAAGCCTTTGTATACCTAGATTTTAGCTTCAAAATTCTCATTAAAATTTGTAATTATATTTTTAATAATAAAAAAACAAAACTATTGATTCTTCTCTTTGTGCATATCTTTTTCTTGTAGCTGCTCTAATGCATTTTTTAGTGCTGGTGGATAGTTAACGCCGCATTTACCTACATTCTCTATAATACTTAATCCTTCATTTGCTATGTAGAAGTAGCAAATCAGAGTACGAAATACCCATGTTCCATCGTTAAGTAGCCTATCTAATAGTACTCCTAAAATTAATACTAATAAAATCATGCATTTTCTCAAAATACCTTTAAACCCTATTTTGCTATTAAGCTTGTCGGTTATATAAGATGCAACCATTCCTGTTGCATAATCTACAAGCATAAACCCTACTAATGCTGCTAAAGGAGTATCCCATGCACCAAAAACATAAGTAAACCATGTACCTATAGCTGCTACAATTCCATTAAAAATATTTTCTTTATTCATTTTGCACCTCTCTTAATAAAAATAGGCAAAATAAAAAGACCTATATGGTCCACTATTTTGCCTTTATAAAATATTTTGTTGTATCGCCTTATTTATCTATTGCGTCTTGATTATATTTTCTTTCTCTTCTATAGTTATCCATTTTGCTTGTACAAAAATATCTAAATCTTCTTCCATATATAGTCCCATTAAAAAATATTCTTTAATATAACTAAGCATTTGCATTACCTCCTAATTGTGCTATTTTTAATAATAAATCTGCATTTAATTCTTTCTGTTTATTTAATTCTATTTGTATCTCTGCATTATCTTTAAGCAATTTTGCATTTAAAGCTTGTTGCTTTTCTTGTGAAATTTCTTCTTCAGATTTTGGCTTTTCAGATAATCTTTTATTTTCTATGTTTTTAAATTCAGATATATAATCATCTTCACTTAATACTGTTAAATCTGAATTTTTAGGGATTTCTTCTTCCATTGTTTTAATAACACAAGTATTTTCCTCAAAATTAACCATTTGGCTTCCTGCAAAGAATTTATTTACATCTAATCCTTTATATTGACATATACCATTATTGTCTATTAAATTAATTATTTTTAAATATTGCATAATAAACCTCCCATTAATAAATTTCAAGCGGTAGCTCATAAGTATTCATTTTTTTTGTTTCACTTTCAATTGGACCTTCTTTTCCTCTTAAAGGTATTAGTGTTTTCGAAGGTGAATATAAATAACATTGCTTTTTTTCACTATTCATAATAGGTATACCCAAATCTGTATACCAAACTGATTCCAGTACAAAATTATTTGCATTAAAAGACATTTTATCAGTATAAAAATAATTATAATTTCCAACACCATTAGTTTTTCTAAATAAGTTATTATAAACTGAACCTGTATTATAATCCATTGTTTGCAATAATATATCTTCATAAGAATATTTATAAAGCGTGTGGTCATTCACTTTAGAATGCCAGAATCCATCAGGAAGAAATAACATATACGTATCATAAGTATCATTTTTATTATAATGAGCATATAAAACACCACTATCTCTATAATATAAAATTGGATTGTTTATGTTACCTGATGTTTTATTTGTATATGCTAATACATATTTATCTGTTACCCCTACTAAATATCTTGTAAAACCTTCAGGCGGAATTGGCAATGGGGCTGGTGCTGGTTTGGCTGTTCCTGTAACACCAAATATATTTTTACCATTTAATATATTTTTAGGTATTAAATTTGGATCACCACTACCAACCTGTGGGCCATCATCATTTGTAAAACTATATCCTTTAAGTGCTTGATTGGGTTTAAGATTTCCACCACCTCCCTTACCCTGTAATATAAAATCCACGCCATTGTAACAAAGATTATATGGTATATTTGATTTTAGATTATTTACTATTTTACCGAAAGGGTCTTTAATATTTTTAGCACCATAATTATTTATATTTATAGTACAGTTTCCTGTTGCATTATTGCCGATAAACAATGTAAATCTAGTTCCCTTTTCTAAACTAGTAATTTTATTATTAGAACTAATATAAGCATTAGTTCCAGTAGCTTCTACTATTGGATAACTGTCCTTCGTAATATCAGCCAAATCCGACTTAATATTATTTATACTTTCAGTATTTTTAGTTATTAAGTTTAATAGATTACCTGCTGTATCCTCCCCTAAAACATCCTTTAAAGTTTTAAGCCAATCTTCAAATTCTTTTTCAAATTCTTCTGATTTTATTTTAAACCTTGTACTGTATTGATTAAATAGAGTTGTAACATCTATTTGATCTACAGTTCCATGCACTATGCCGCATAAGTTTTTATCAAGTCTTAGATCTGTTATATTAGCCTGTGTAATACTAATAGCACCTTTATTAACAGCCACATCTGCTAATGCTATCTCATATGCATCTGCATCACGTTGAAGTGTTTGGGCGGTTGGAGAACTTGCAAATTGTCCTTTTTTTACATAAGAATATATTTTTCTTTCAGCTGTATCCATTCTTAATACAACTTTATCTATTCTATTTAATACACCATCCGCTACGTCTATATTTAAAATATAATCATCTGTGTTAATATAAATTGCTCCATTAATCCACCCCTTACCGGCTTTAATTGTTATAGTCATATCATTATTAGCTATAACTTGCAGATTATTGCTTGGATTAGGGAACACTCCATTGCTTATGAAACTTGCAAAATATTCTCTAAAATCTTCCGCTTTATACCTTCTATCTCCGTTTACACTGTTAAATACAAAGCTCTTTTCCATTACTTCTTATTTCACCATCCTTTTTAACACAGCAAGTAAACTTGGTATTCTTGTACCAAAAGTAGCTTTAAGTTTCATACCATCATTACTATACACTTCCTGTGCTTCTATAATTCTACTATCCATAGTTACTTTTAATTTCTTATCCTGGATAGTAACTATATCCCCTAAATCATAGTCTTTTTCGTACACAAATGTATTGTTTGGATTAATTTCTAGTTCAAATGTTTTTAGCTCCTTAATTTCTTCAAGTTTAACTAAACCTTCTTTTTTTATATCCTCTACTTCCTCTGATGTACTATCTAAAAATGTTTCCATTCTTTCAAATCCAGTTATATCACCAAGGTTTAAAACTAGCTTTTCTTTATTTCCAATATAAATAGAATTTCTACTATTAATAATGCTTTCCGTATAATGTCTAGTCTTTATATTATTAAAATCGTTTCTGAAAATAACAGGGGGATTGCTATCTTGATTAACTGTTAAATCTTTCCCTTGTAGCACATCAAATATAAATTTTTTTTGCTTATGATCTAGCATAATGTTCCAACCAAGCTTACTGTATTCTCCTATTTCTTTTAACTTCTCGTCTAAATTTTCATACGCTCCCCTCCATCTATCGTCCTCACCACGTTTTTTATCTACTGCTATAATCAAATTATCTATTTTTCTATTTGAATCTATTGGATTAACACAGTTTCTATTTATGAAATATTTCATTATAGTTTCTTGATACCCAATACAGCTATCAAATTCTTGTCCTGTATTAGGTATTATAATTCTTCTTTTAGTTAATCCTTGAAGCATTACACCTTTTATTAGAAGTGTCTCTGTTTCCTGTCCTTCTTCTCCATAAACAAACTCCCTGTGTAATATTACACCCACCTTGTTATAATCTTTTCCTAAAAGAAGTAAATTATTTTTAACCAACTTGTCTGTATGGAGTTTATTAGAATTAATTTTAAATTCAAATTCTCCACATTCAAAAAACCTTCTAGTTATAGAAAAACTTTCATAATTGTCTATAGCACCTAATAAATTTATATTCTTATCTAATATTTTAACTGTCTTAATAATCTACACCCCCAAATATAATGGCGTGTAATATATGGCCACTTCTAAATTATCTATGCCACTATCTGCATTGTATCTCAAAAGATTGTCTCCTGGCTCTAGCTGTAAGAACTCTGAATCTAAATCAATCCAATTGAAGACATTTTCTCTAGAACCATTATTTCTAATCATTTCTATTCTTTTATTACTAAACTCTGTGGTACATTCCAAAACATCTCCTGCATTAAGTGTCTTATTAATTTTTATAAATTCTCTAGTATTGATGTTGAATAGACTTGGATTTATTACTGTTGCTAATGCCTTAAATTGTATTCTCATGCCGCACTCAACAGCTCCAGTATTATTTATATTTACAATTAGATTGCTAACTCTATGTCCCATTTCTATACCTGTATCTTGTGGTATTTCTAATGGGAATTCAAAATCACCAACCCAAAGTGCAACTTCCTCTTTCTTAGTGTATATATCCTCCCAAAATGGATTAGGAACTAAAATCTGGACTAAAAATTTTTGAATAGATCCCACTTTATCTTGAAAAGTTATATCCTGAACCCTTCCTTTAATTTTTCTACTAGTTGCATTATTTGTATAAATGAGTTCTCCATGAAACTTAGGGTTAAATACACTTGTTAAATATTCTCTTTTCCTATCTATATCCTCAAAATTATTACCTACTATTCCTCCTGTTATAGGTAATAATTTTTCTTTAATAGATATATTATCTATACTAACTCCATCTTGTCCAGCGCTTATAGATGTATTTATACTAGTTGCTGTATTAGCTACATTTTCTATTTTTTCCAAAACAAAAGGACGAGAGTTACTTAAAGTTACTTCTTGTCCTTTAGAATTTCTATATATTAATTTTTGCAACTCTAATCCTCCCTACTTATGCCATAGAAAAAGCTAAACTTCTTAATTCACTTTCTATACTTCTACTACCTCCATTATTGCTAGAGGCATATACATTAAATGTATTATTTCTATTATTAGTTACACTGCTATTTGTAGTAACGCTGCTAACACTTCTACTTAAATCTAAAGCATTTTGCCTTGCTCCATTTATTTCAGCAGTTATACTTGCTATCATATCCTTAATTTCTTGAATTTTGGGACTAAATCCATCAACTAGTTTTTGTCCTAGTGTTTGCCCAGCGTACTCATATTCTTTACTATAACTGTGCAATAGCTCTACTATTTCCTTTTGGTTATTATCCATAATCATTTTTTCAGCTTGCGCTTGCAGAACTGCATCCTGTGTTCTTTTTTCACAAAAAGCTCTATAATCTTCAAGTTGTTTTTCTAAGCTTTTCTTATTACTTTCATATATAGAATTAATATTTTGTAACTTATCTTCTTTTTCTTTTTCTAGCTTTTTCTTCTGTTCTTCTAACTGTTCTCTGTGTAATCTTTTCTCTCTTTCTTTAAGAAGATTATTAAGCTCTTGCTGCATTTCTGCTTTATTAAACTCATTGTGTTCAAAATCAATAGCAGACTTAAGGCTATTAATTTTCTTCATTTCTTCTGCATCTTTATCAGCTTTGTCTTCTTCCTCTAGCTGTTCTTCTATAGCCTTGATTTTAGCGTCATATACATCATCTATTCTTTTTATACTTTCATCTTTCCACTTTTCCAAATTTTGAATTTGACTATTTATAGATTCCTCTTGTAGTTTTAGTTCATCTTCATATCTTTCTTTTAATGCATTAGCGATATCCTGCTTAAACTTATCTATATAATCTGACAAGTTCTTAGCTGCATCCTTTACTGCATTAGCCATATTTTCTAATTCTACTCTAGCATTTTCAAATTCTTCCCTAGCCTTTACTGTTTCTTCTGCTGCGATTCCCAAAGTATAAGCTAAATCCTCATAACGCTTTCTTAAGTCTTCTACTTTTTTACTCTGTACTACAACTATAGCCTCTTGATTTTTCAAATCTTTTACTAGATCTCCTGTTTTAACTTTTAGAGATTTAATTGCTGTATCATAAGTAATCATTAAATCTTTAAATGCATTTTCTTCAATTTTCAATGACTTTTTAACTTCTTTTTCTCTCTTGTCTAATAATTTAATTCCATCATCATAGTATTCTTTTAATGCTCGCTTAGAACGCTCAAGGCTATCTACCTGTGCTTTCTGATTAGCTTTAGTAGTGTTTAAGACTTGTTTTTGGTATTGTCTTAAGCTTGCTATTTGATTAGCATAATTCTTTTTAGCGTTTTTATCTTTAGTATTCCTTTGTAGATTTTGATAATGAGCTATTTCTTGATCTACTCTAGCTCGTTCCGTTTGTAGCTCTATGCTATTTTCATTTTTAAGTACTCTTAATCTATCCTCTACATTTTTTACCCTATTTTCGTAATCTTCTTTTAAAAATTCCTTTGACTTTTCTACTTCTTCTTTATTGAGTTTATCTACAAAGTTTAAATATTTCTGGTATTCATCTTTATTATAAACACCCCAATTCAGCTGCCTTGCCACTCTATCTTTTATTTCTTTATCATTTGTATTTACCTTTACTTGTATATCGTCTAGCTTATTTTCTGTAACATCCTTTATAACTTGTGCTGCCAGATTAGCTGCGCTTTCTACTTTATCTTTGTTTTCCAATATACCTAAGGCTAAACCTTCACTTGAAAATTTCCCCAGTTCTTGCATGACCCTTGAAGGAGAATTTATACCAAGTGCTTTTCGTGTTTTTAAATTTATTCCATTTGCTGTTTCTAATATAGAATCATGTACTAATTTTCTAGTACTACTTATCCCATTTGCTAAACCTTCTGAAAGATTAACTCCCCATTCTCTAGATGTTGCATAGCCAATTTTATTATCTAATTTATCAAATAGAGCCATAGTGTCTCTGTTATTTAAAACTGTTTCTCCACCACCAAACCACAAAAGCTCTGGTCCTTCTTCTCCGACCATGTGCCATCCACGTGTAGCGTTGGTAGTACCTGTTGCATAACCTGTTTTCTTTTCATAAACTCCTTGGGAATTATCTCTTAAATTAGTGGTCATTTCAACCTTAGGATGTATTATGTGTTCATTAAACCAATCACATATATTTTTCCATGGAGTTTTTATTTCTCCTGATTTCTCATCTATTTTTTTACCAACATCTGTACATTGCTTGCCAACTTCTTCAACTACTTGTCTATGCATTTCCTCTGCTTTATCAACACTTTCTTTTCTCTGTCTTTCAGCTTCCTTCAACATCTTGTCGGCCTGATCTTTTGTTATAACTTTAGTTTCATCTCTCATTTTTATGATGTTTCTAACAGTTTGGTCATATTGTTGATTAGCCTTATCTACAGATCCTTGTCTTTGTTTCTCTGAGTTTTTAATAACTTCGCTCGCTTGCTCTGCTGTTATTCTTCCATTGTAGTTTTTTAACCTTTCCATTATTACCTTTTGTTCTACTTCAGATGCACTTAATGTTTTAACTGCATTTTCTTTCATTTGTTTTTGTAGCCCATCTATCGTTTGAGCTTCTTCTGCTGTGATCTGTCTATTATGATTTGCCGCATGTTGGATAATTGAATTAATTTGATTTTGTAATGAATCTACTGTTTTTTTCTTGTTTTCCCAACTAGTTGCGGTTGTTTGTAATATTTTGGCCTCTTCAGTTGTAGTTAAAACATTACTTTTTGAGAAAAAATCTTGTTGGCTTTTTAATTCTTCCGCTTTCTTTTTATCCAATCCAATCTTAATTTTGTCTCCCATATCCTTATATATTTTTTGTAAATTAGTGGACTGTTCCTTTGTAATTGCAGTACTTTTATTTAAAGTATCAGCAAAATCTTTTATAGTTTGCTCTTTTTGTTTTTTAGTAAGGCCTTTTGTTCCATTAACCATTGCTGAGTACTGCTTTATAATTTCATCCTTATTTTTCTTAGTTAATACTCCAGTATCTGAAACTAATTTTTTGAAATTGGTTGTCATGGTGTTTTTTTGTTCATTGGAAAGCTTACTAGATTTTTTACTCATATCAGTAAAATTTTTCAGCACTTTATCTTTTGCTTGTTTAGTAAATTTATCAGAATTTGTTACTAAATTTAACATAGAACTGCTTGCTTTTTTATCTAGATCCATGTAAGCCCCAACAGCTTGCTTAGTGGATTTGGATATTTTAACATTTGCAGTTTCAACACCTTTAGATGCAACATGATAATTCATCATCTCACTAGAGCTTGTTTTTACCTTGTCCGCAAACAAGTCTACACTTGGTATCACATCTTTTTGTAGATGTTTATATAATTTAACTCCTGCATATATTGATCCTCCTATTGCCCATGTCCACGGATTCAATAGTAATGTTCCGGCTTTTACAGCTAATCCCATCCCAGTAATACCTTTGCCAGCTAATCCTGCAGCTACACTTGCTGTTGTAGTTGCTGCTTCTGCTCCTTTTGTAGCAAGTGTTATCTTACCTATTATTCCAGTTACTTTACTCCCAACACTTAAAATACTGCTAAATCCAGTTGCTAATTTTCCCACTCCTACTATAGCAGGGCCTGTAATTGCTACAAATGCACCAAATTTAATAATACCTTTTTGCATTTCTGGGCTTAGCTTAGAGAATTTTTCTGTCATTCCTGCCACGCTAACTGCTATATCTCTTATAGCTGGCAATAAATTCTTACCTATGGTTATACCCGCATCTGTTATTTGATTTTTAGCCATTTTTAGTTTACTTTCTGTAGTTTCGTAGCGTTGATTAGCTTCATTAGTTAATGCAACATTTTCCCCCCATGCTTTAGTACCCATATTTATAGAATCTTCCAATAAAGTACCTGCGTTTGCTGCTCTAAGCAAACTGTCTCTAAGTCTTACCTCTTTTATGCCCATTTCTTCCAACATTTCTATTGCAGATGAACCAGCATTTTCTGCATTACCTAGTCCACGTATAAAGGCAATAAGCGCAGTGGCTGCATCTTTTTGGAAAGCTTCTTTAAACTGTTCTCCAGTCATGCCTGCTATTTTCCCAAAGTTATCTAATTCCTTAGAACTCTTTATTATTGAGTTCATCTCTCCAGTAGTCATGTTTAAGGAATCTGCAACTTCTTTGAATGCCTTCCCTTGGTTAGAAGCCATTAACTCCAGTTGTCTTATAGTCATTCCGGTGGATTTTTCAAGTTCTTTAGCCTTGTTGCTTCCTATCGTTGCAGCAGCCTGCATTTTAACCATTACTTTACTAATAGCTGAACCACCCATTTCAGCTTCTATACCAACACTAGAAAAAGCTCCAGATAGTCCTAAAAATTTGTCCTTCTGTAAGACCTATCTGTTTTCCTGCTCCAGCAAGTCTTAAGCCCATCTCAACAATTTCACTCTCTGTTGTAGCTAAGTTATTCCCTAAGTGAACTATTACAGAGCCCAGTTTATCAAAATCTTTTTGGCTCATTTGAGTTATATTCGCGAATCTAGCAAGTGCAGTTGCTGCTGTTTCCGAGCTCATATTTGTAGAATCACCAAGCATAACCATTGATTTAGAAAATTCTAGTATATTATCTGTTTTTATTCCTAACTGCCCCGCTGCCTCCGCAACTCCTGCAATTTCTGTCGCAGATTGAGGCATTACTTTACTTGTATCTCTTATGCCTTTTTCTAAGTTTGCAAATTGTTCTTTAGTCCCATCTACTGTCTTTTTCACTCCTGCGAAAGCACTTTCAAAATCTATTGCCGCTTTTGCACTTCCAATACCAACTGCTGCGATAGGAAGCGATAACTTACTTATACCTTTCCCTACATCAGTTATCTTTTTTCCAGCATCCTTAAATTTTTCAGAATTATCCTTTAATTTGTTACTAGCCTGTACCCATTTGTTACTTTGCTTATCTATTTCTTTGCTTGTACTAGATAAAGAATCCTTAAGATTTTTTAATTTAGTTTCAGCATTATTAGCTTTATTAGTCCAGTTATCTATTGACCTAACATTATTTCTAAGTTTTTCTTCGTTCTTAGTATACTCAGAACTTAATTGTTCATATTCACTTTTAAGCTTTTTAGTTTCCTGTGCGTTTTCTCCTAAAGTTTTTTTACTATTTTCGTATGCATCCTTAGATGCTTGCACCTTACTTTTTAGTTGTTCTTGTGCCTCTGCACTTTTACTTAAAGTATCTTTGCTTTCTTTTAGCTTATCTTTATATTGTTGTAATATTTTACTTTGTACATCTATGGATTTACTAAGCATTTCTTGCTTAGATTTGAGTCCATCCAACCCTTGTCCATGGTCCTTCAATCCAGCTGTAGCATTTTTAAATTCACTTTGAATCACTTTTATGGAACGATTTAAATTCTGTATTCCTTGTTGAAAATTGCTATTATCCATCGCTACACGAACAACTAAACTTCCTACATCTTCTGCCATTTACTTACCTCCTTTCTTGCAAAATAAAAAGAGCCTAGAAATTAATCTAAGCTCTATAACCAACTAATCTGGTCTATATAAACATCTTCTTCTTTTCTTTTGCCTGTTTTACTAATAGTTTTATTCCTATAAGCTAATACATCAAAGTAATAGAATATATCCATATTATCTATATCAGTCATAGTCCATTTTTGTTCTAATAAATTGCTATATAAATCTAAAATAAATTCTTGTGGAGTAAGAGAACTACCTTCTCCTTCTCCACTAGCTAGTTTTTTATTTTATCCTCAAAGTTACCTAACACCCTTTGCATATCTTCTATTGCTTTATTGGCAAATTCATTCGCTGGAAAGCCATCATATAGCTCGTCTATAGTAAACTGGTTCCCATATATCTCAACCAAATGTTCTGCTACTTCATCTATTGTTTCAATAGTAATTCCATTGTATATCTTTTCGCTTAAAGCCAAAGTTTCTTTTAACCTTCTTGTGCTTATGAAAGGTGCATTAAAAATTTTTTCTTTCCCATCTATCAATAATGTTATAGTTATTGTCATTCTAATTCCCTCCTAAATTTAAATAAGCAAGAGCATTAAGCTCCTGCTTCTACTGGTTTCTTTCCTGTTTTTAAGAAGTCAACACTAAAAAATTCTTCCTCTGTTGGTGCTCCAGTGATGTTTGTATCAGCTTTAAATTTATGCTTACCATCTTTCACTCTAGGCATAAATACAAACTTTGCCTTTTGTGTTTGGAATTCTACCTTATCGTCTTGCGTTTTAGCCTCATCGCTCATAGGTTGCATTTTCCCTTTTAGTAACCAAACCATTCTTTTTCCACCACTAGACTTAGGTGCCATGAAGCCAAAGGCAATATATGGGGGATTAAAATCTTTATCCTCTATTAAGACACCATTTTCATATTTATATCCTAATAACTCTGCTTGTTGTTCTAATGTCAAGTCTGCTACATCAATATCTACATCTATAGAGCCGATAGCACTTGCAGTTTCTAAAAGCTGGTCATCCCCGTAAAGTTTAGCATCATTTACTTTATTATCAACCTTTATACTTCTAGCACCTGTCAATCTTTTAATTTCTTTTTCATATTCAAATCCTTTTTCGTCATCCTCATTTAGAACACAATAACGAAACCCGTGTAATCCTTTAATAGCCATTATTTTTCTTCCTCCTTATTTTCTACATAATAAAAGAACCTTAATACTTTATGGAATATTCCTGTATCGGGTTCATATGGTCCATCATGGATTGTTCTTTTAATAAATCCATTTGCTTTTAATAATTTCACTGTATCTTCTTTTAATTTTTCTATATTCCCTTTGCTCCATATATCTACTTGCATATAAAATCCTGTATCAATCTCTATGTCATCCGCAAAGCACTCCCCTTGCTCGTTATAACAGAAGAAAGTTATATATGTTTCTTCTTTCCCCTTATAAGTTTGAAAATTCACTGGAATGTTTAGAGGCTTTAAAGCATCTATTATTAATTTATTTATGCTCATAGTCCTAATCCTCTTCGTAGTTCATCTTTTATTATTCCTTTAGCTTCTTCTTTTTTGCTCTCGTACGCAGGCCCCATAAATGGCCTTGCCTTCATTTTGCTTGTACCAAACTCCAAAAACTTTCCATAAAATATTTTAGAATTATCTCCCTTTTGTATTCCAGCTAAAACAAATTTATTTCCACCTTTTTTACGAACACCACTTACCTTTAATCCTTTTTTTAATTTTTCAGTTTTAACCGGCACATTATTTTTAGCCTCTTCCACAATTAATTCGCCAGCTTTTTTAAGAGCTTTATTTTCTATCCTAGTTCCAGCCTTGCCCATATCTTCTATTTTTCTAATTAAGTTATCCATGCCTTCAAGTTCCATATTAGCCACTTGCTTTCACTTCCTTTGCATGTATCTCATATTCTACATGCCTTTCATTTAAATCATTTATAGAAGTTATATCATAAAACTTATTTTTGTATTTTATTTGTAGAGAGGTATCAAGGCCTTTAAAATACCTACAATTAAATATCTTATCTTGCTCACTTTGCACTGCAGCAGCATTATAAAATTCTCTACCCCTTAACCCTCTAACGCTAGCCCAACATTCTCTAATTGTTTTCTCTCCTTTTATAGGATATCCTTCATCATCTGTACCATTTTCTATAATTATAAATTTAATTCTTTTATTAAGTTTGCCCGGATCCATCTGTTGCACCTCTTTTAATTTTTAAATATTCAGCTTCTAGTTGGAGTAAAATCGAATCCACACCAAAGCTTAATTTGTGAAAGTTAGGGCCTGTAGTTTCAATTGCTCTATTCTCATTCCAATGGCTTACTAAAATTTTAATACATAATTTATATAACTCTAATATTTCATTGTCTTTTATCATATCCTCTGTTAAGCCTGTAGCACCCTTAATATATGCCTTTGCTGCAAGTAAAAGGGAAGGAATTGTTATTTTCTCTCCCTCATCTTCTTCTAATTTTATATATTCTTTTAATTCATTTAAGTCCATAAAAATAACACCTCCTCTAAGGTGTCAATATTGCTGTTATTAAATCAGCTTTATTCATACTGGAATATCCAACTATATTCTTATCTTTAGCTATAGATTTTAATTGTTCTACTGTCATAGTCTCTAACTCTTCTTTACCATATATTATGGGTTCTGTATTTTCTTCCCCCATCGTTTCTTTTGGGGGCTCACTAGGGAGTTTTCACCTTAGCTATTCTAAACGCAGATTTTAGCTTGATTTGATGGTCAATCCATGCTGTTAGAACGAAATCTTCCATGCCTGTTCTGACATTCTTATCTCTATCATATAGCATATCTAAGTCGTAGTTAAAATGGGAATATCTAAAGTCCCCGATAACTGGATCAACTGCTTTGTCGCAGAACTTAACTGGTGCTCCTAATACCTGTTCTGGTTGTGCCCCATACAATGTCGCATTCCCATTAGCTAAAGTTTCTATAATATCATAATAGTCTTTTCTAGTCATGCTTATTGTAGCATTTTCTGCGTAATCGTCCTCTAGGTCTGCTAAGGCTCCTTTAATAGCTTTATATAAATTCTCACCTTCTATTATTTTTATATTATTTTGAGGGCTATAGAAAGACATATGTTCTTCTCCACTCTTAGGTGTTTTAGTAAATGCTACTTTTTTCTCTTTAGCAGCTATTCCACTTTCTAATGCGGCATCAACAGTTTGTACTAAATTAGTATTAGTACCTCTTAAAATTGTTTCAGATAAACTAGAGAATACTTTAAATTTATGTCTGCCAAATTGTACTGTGGGAGTTTTAACTTCCAGTTCTTTAGCTGTTTCGGTATCTTTAATAAATTCATCATCATCTAGAGTAAAATCAATTCTAGGTACCTCTAAATTTGTAATATTCGTAAATACCGAAACATCTCTTAGCGGGTTCTTAACAAAAGGTTCATGTAATAATTCATTTGTCATAGTTCGTGGTAATATTTTTTCTCCACCAGAACTATTACCATCTCCTAAAGCCGCTTTAATTTCTACACCCACAGGTTTATTAGCCATTGTTGCTCTAATTAATTCAGCCTTAGCATTAACTACTTTTTCTTTTTCTGTATCTCCTGTAATATTTTTATTTTTAATTTTTTCCTCTGCCTGTCTATCCATTTCTTCTATCTGCGCTTTAATGCCTGCAAATCTTTCCTCTAAATCCTTAACAGTATTTTTTTGCTCATTCCTTGCTTCTAAAGTAGTCTTTGCATCAGCATACATTGTTGTTAGCTTTTCAGTATTTGCTTTTAAGTCCTGGCCTATTCCTGCTAACATTTGTTCTAATTGATATCTATTCATTTATTCTTTCCTCCTCAAATTTTAAAGTATTATTTACTCTTTCTATAAGAGATTCTATCTCTTCATCTTTAATAAAATTGTCTTTATTTTCTGGTTCTTTTGGTTTTATTGACTTTGCAAATAGATTTTTGGGCATATTCTTATATTCATTAAAATATTGGGAAGTACAAGCTACCAATTCTTGTGTTTCCTCAACTTCAATATTGAAATATTCTGCTGCCTTTTCACCTGTCATCCATGTTTCATCAGCCATTAATTGTTTAATTGTTTCAATATTTACACCTTCATTTAAATTAGCTTCATATATTTTTAAAATGCTTTCTTCTGCTATATCTAAATCATTAGCTTGCTTTCTGAATTCATTTGCATTTCCTAAAGCAATAGTCCAGGGCTTATGAATCATAAATTGTGCTGGGGCAGGAATTACAACTTTATCTCCTACTAGTGCTATTACACTTGTTATACTTGCTGCTAATCCATCTACATGGACAGTTTTAAAACCATTATGTCTCTTTAATTGATGGTATATTGCCAATCCTGCGAATACTGAACCTCCACCAGAATTTATATAAATATCTAATTCTTTATTATTATCAATTTCTTTTAAAAAATTAGATACATCCTGTGGACATTTATCTTCTTCTTCCCAACATCCCCAAGTGCTAGAACAAATATCCCCATAAAAATAAAGTTCTGCTTTTTCTTCTGTTTGATTTTTAATTTCCATAGTTCCTACTACTTCTTCTTTTCCAGTTTGTTTGTTTTTATTTTTAAATTGTAAGACTTTATTCATATTCTCACCCCCTTTCACTACAATAAAAAAGAACCTTATCTTTTCGGTTCTATGTTGTTATTTTTTTGTTGTAACAATAAATCAATTTTATCTATTGGAATCAAATCCCTTGATACAAATAATTGATCTCCACCTTTTATCGGTGGCATTTCTTCCAAAGCTCTTATTTCATTAGGTGTAAACCAAGCACTCCTAATACCTTTAAAATAAAAAATCTCCTCTAGTTTTCATATCTGCTCTTGCTAAACCATTGAGATTAAACTTCCAGGAGTATCCTTCATTTCTTTGAGTCTCTGTAAGTAATTTCTTATTTAGTTCTTCTTCATCCTGTCTTATATCAGGTAAAATGGTATCTTTTATATATTCTAGATCTGCCTGTTCAGCGCTAGAATAACTCTGCTTTTCAGCTAGTAACTTGTGCAAGGGTATATTATAAACCCTCGCTACTCTTGCTATAGTTATATTTTCAACATCAAAAACCTTAGGATCTATGAAGCTTGAATTTTTAAGTTCTTGAAATTCTTTTCCCTGATCCACAAAAAGAATTCCATTCTTCTGAAACTTTCCTAACATTTCTGTATACTCGTCCATAGATTCTTTACTTAATTTAGCGCCTAATTTTATAACCAAATTTGCTTTTAGTCCGTTTTCCATCTGATTTAAGCTAAATTCTTTAATTTCCCTATCATAATCAATGGTATTTCGTAAAACATCCAAGGGGCTAATACCTTTGTACCCATTCATAGAAATATGGCTAAAATGTATTATATGAGAATTATGTACATATCTTAAACCATCTTCATCTCTGATTTCGTAATACAAATCCTTTGTATCTTTTTCTATTACTGGTGTTACAAAATCAGGGTTTAAAACATGCATTTTTATAGGCTGATTCATGCAATCATACTCTTTTATAGCATATGCATTTCCTTTAGTATTTTTTAATGTCTCCATGCACCTTACCCATTGGAACATAGTCATGTACGAATTGGGATTATACTCTATCATTCTTGCTAATTCATTTTCAGAAGGTTTTACAACTTCATAATTTTTATATAGTTTAAGTGGTAAACTCCCCTTTGTATTACTTAATAACGATATGGCAGAGAATATAGTTTCATTGGTAGCTAAATCGGTATTAAAAAAACTAAATCCACTACTATAATCCCTAATTATCCTTGTTTTAAATGGTGCTTTAATTAAACTCTTTATCTTATTCCATATTCCCAATCTTCCACCTCCTCTCTATATATCCGGGCTGTAAAATATATCTCCTGCTCCATCATCTAGTACTACCATACCTCTTACATGTGCATTTATTACTGCAGCTGCAGGATCTATTTTTTCGCTACTTTTTGCTTTATCTAGCATTATAAATTCTTGCGCATTTTGTTTAGTTACCGCATTGCCTATTGCCCAGGTTAAAAGTCCATCTCCACTATGTTCTAACTTTTTATCATATACCTGGTCTCTAAAATCTTTAGTAGGTTCATTAAGTGTATATGGTCCTTGTCTAACTTCAACCATAACATAACCTTCCTGCTCCATTTCCTGTACAAACTGTGTAGCATTGTATGGGTCATATCCTATCTCTTTTATTTTTAAATTGTATTTCTTTTCCTGTTCCTGTATCCACTGTTTAACAAAAGCATAATCTATTACTGCTCCTGGAGTTTTAGTTAATGCTCCTTGCTCCTTCCATAAATCAAAACGATATTTTCCTTCTCTTACTCTCTTTTGATATGTTTCATCTGGCATAAATGAATGTTGGAACGGATAATATTTATCATTTCTTTTGAACTCAAAGGCTATAGAAGTTAAATCAAGTTTAGTTGATAAGTCTAATCCACCAACACATTCTTCTCCTTCAAAATCAGCAAAAGTTAACTTATTATTTTCACATTCAGCCCACTTTTGCATGTTCATGTAGCCGGATTCCTTCATGTCTACCCACTTATTCATGTTCTTAGTTAAGAAGTTTCTCATCTTCTCCGGTGCGTCAAGTGCTGCTTTAAGTTCACCTCTTAAATAATTCAATCCATTTTCATAGGTAGCTACTATAGGGTTAGCTTTTATCCAATTACTTTCATCCTTGATATCATCTTCAATATCAAGTTCACAGATCATTACAAAATATTCTTCATTTTCTGTAGGGTTATTAGGATCAAGTATTTTACTAACATATTGATATTCTTTAAAACATGGTCTGCTTAAATCAAAACCTGCTGTTGTTATAATAACCATTAAAGGTTGTTCTCTAGCAACCATACCGGAAAGAATAACATCATATATTTCAGAAGTCTTATGCGCATGATATTCATCAACAATACCTAAGCTTGGGTTTGTACCATCACCAGTATTCTTAGCTTCACGAGATAATGGCTTTATAAATGAACCGCTCTTTAAATGAGTTATTCTTCCATAACTATCAGTGTATTTACCTTTTAATAATTCAGCACTTTCTATTTGATACTTTATTTCTCTGTAAACTATACTTGATTGTTCTTTATCCCATCCAGCAAGATAGACCTCTGCCTGTTCCTTGCTTAAGAAGCATTCATAGCTGGCTATTACTGCTAATAACTGTGACTTAGCATTTTTTCTAGCTATCTGAATATAAGCCTTTCTAAAACGCCTTAATCCAGTATCTTTATGTTTCCAGCAAAATAAATTTCCAACAATAAAAAGCTGGAATGGCACAAGGTCAATTTTCTTTCCTTTTAGCACACCAGCTCTATGTTTGAATAATCCAGCCCATTTATAAAATTTGTATAGTTCTTCGTAGTCAAAAAAATAAGGATAGTCTTCATTTTGAGACTTATCCAAATCATTAAGGAACCTTTTACAAGCTTGTATATGCTTTTTACAAGCTTTAATTTTCCCGTCTACAATATCACATGCATACCTATAAATTATAGTATAATATCTAGCTATATCACTCATAGGGAACTACCGAAAAGTTTCTCCTCTTCCGTCTTTTTATTCGGTTCCTCTTTTTTAGGTATTACAAGTTTGCATCTGCTACTTATAGTTAACCCTAAATCACTGGCAGATGATCTACATTGTTTAAATAATTTATCCTGTGTTGTTACTATATCTTTATCTACTATCATCAATTCTGGTTTTTCAAGTATCTGCTTAGTAAGTTCTAAATACATTTTCTTCGCTATAATAAAACGAGCCAAGGCATCTATATCAAGATTAGTAATAATACCAATCTCTTTTAGTTCCTTGGCTATCTTATTAAATTCTTTTTTTAAATCAGCTGGCAAGTAAGAAGGTGCTTTGACCTTATCACTTGGAGCTTTAATTTCTTTGCTTTTCCTGTCTTCTATTTCAGCTTTAGTTAAATGTTTTTTACCTTTTACTAAAAGTAAATCTGTAGGTTGTCTTGGTCTTGCTATCCTTCTCACCCCCTATTTATTTAAAATAAAAAAGTTAATTACCTGCTCTACATGCTAATATAATATGGGTAAGGATTTGCACCTTACATGACAGCTGCTTCAACTCATGTCTGTGCTTAACTGTCAAGCCGACCGCGTTAAGAAATACCTATGTCTACCTATTCCACCACCATATATATAACATAATCTCGCTTTGAAAATTTCATTTAGGGAATTTTTCACGAGGGAATCTACTCCCTCGGTCTTTTAGAAGAACGCTAAATTCTCTAAGGGAGGGGGGATATACCAAATTGTTTTATAAATCTTTCTAGCAGCTCTACAAGAAGCCTTTGGGTTTCCTTCTTATCCTTACTATAGAGACTGTGTATATTATTATGTGTAACATCTGATAAAGGAAATAGGTTGTCTACATCTAACCTTTTATCCCAATTATCTTTTATCTCTTCTATATGATGCACTGTATTAGCAATTACTATTTTATTCTCTATATAATAACTATATATATCAATTCCATTATAAGTTTTTAAAATATCTTCTCTCAATCTTTCCCATTCTTTACTATGATAAAACTTAGTATACTTCTTATCCTTGTTATATCTTATACGTTTATCATAGTGTTTATTTCTTTGTGCTTTTCTTTCCTCATATATGTGTATATGTTCCAAACAGTATCCTGTTATATCTCTTGTTAGGTTCTTACACCCACGTTGCTTGCATGGTCTTAGACTACGCTGTGCCATTACTCTAAAGGCTCCATACTCATTGCTGCTTCCACGCACCTCTTCATTATATCTTTTATGTCTATATTATTATTTATTGTTATATTCTTAACCTCATTAAAGTCCTTGCTAAGCTTTAATGTATCTTCTAAAGACTTTATTCTCTCTAATTGCTCTTCTAATCTATTTAACTTATTATCAAGTTCTGTAGTATCTAAATTCAATTTAATAGTTATTATATTTCCCATTTTCTTAGGTTGTTTCCCTGGCGGTTCTGGTCTTGGCCTTGTAGTAGCTTTAACTCTTTTAAACATTATCTCATCTCCTTTACTATGTATTCTTTCTTTTTATTTATCCAGCATTTCCTTAACTTTATTTAAAGATTCCTCAAATTCCAATGCAAATTTATAAGAAACTATCGCTGCTAAGCTTGAAGCTATCTTTAATTGCTTTTCTGTTTTATTTGATTTACCCTTGCTATCTAATATATGTTCGTTGAAATACTCTACACTATAAAACATAGGTTTATCTCCTAAACCTACTGCTATAATAAAGTCATATCCTTTCCTTAACCTGTCCCAGTTCTTATCTATTTCTTTAATCATTCCCTCACATATGCTTGAAGCACTAACACTATTTAATCTTATCTTTTTATACTCTTCCTTAGTTATTATTCTATAATCTAACATTACAACAACCTCCTTATACTATTAAATAAAAAACATTCTACTGAGCACCTAACATTTTACCTTTTAATATATCCATTTTAACTTTAACTTTTCCCTGCAATTGTTCTATATCTTCCCTTGAAACTTTACTCCATTTACTTCTTAACTTAGCTTGTAATAGTCTTATCTCCTTATCTGTGTAAAAACAGATATACTTTTTACCACACTTAGGACATTTAAAATAAGTTTCTATTACTCCATCTTTAAGTTTTCTTTCTTTAAATTCTTTTATTTCAAACTTCTTCTTACATCCTTTATCACAATATGTTTCCATAACTAATCTCCTTTCTAAGTCAAACATATCTAATATTCTGTTAAACTGTTCTTAATCATATTAAACATTTATTTCCCAATGCTTTAATACAATTTAGTAAAAATCAATTTAACATAGGCTCATTATGTTAAGCCTTACTGTTTTAAAAAAGATTTAAATAGTAAAATTTCTTCGTGCTTTATTCATTTGATCCTGTATTATTCCAATATACTTCAAGGTTATGGAAGGATCGCTATGGTTGAACATCTTCATTAGTGTTGCAACGTCTTTACTTTGTTTATAATAATGATATCCAAACGTCTTTCTTAATGTATGTGTACCTAAATTATCGACCCCAAAATCTTCACCGACCTTCTTAATAATTTCATAGGCTCGTACTCTTGATAAAGCTTTATTAATACCTTCTCTACTTTTAACTAGGTATTCATCTAATTCTTTATCGGTACAATACCACTTATATTCTTTTTCTAAGAACTTATTTATTTCTATAATATTTTGCTTAGATGTTTTCTTTTCTCTAATATATATAAATCTTTTGTTTTTTACATCCTTAATTTTTAATCTGAGTATATCTGATATTCTTAATCCAGTATAAACTCCTGTAATAAAAAGAATGTAATCTCTATCATTTGTTCTTTTAAGATATTCCTGGATATCTCTTACCTTTTGGGTATCTCTTATAGGCTCGACAAAATTCATTTCATCTTGTCACCTGCCTTATCGCTCCACGTACTCTTTTATAAACTTTTTCTTTCATACATTCCTTTAAGTTATCTGTTGAATTTTGTTTTTTTACCTTTCTACTTGTACAGTAAGGACATACTAAATATCCTTTTGTTCTTTCTAATTCTTCTGATAGCAATATAAATTCATTTCTACAACTATAACATAAAAAGCCTGTATACATACTTAGCATATCCTCACATCCTTTCATAAATAAAAGCACCTAAGGCTTATACTCCTTAAGTGCTTTTAGTACATACACAATATATTATATATTTTTTTATTTTCGCAGTTGCCTTATTGTACGATAAAACCCCTACGTGGGCTTTTAACCCTTATATCATATGATATATTACCTTTCCCATTGTTGCATTAATTTTTTCTTTAATTTTTCTTGATTTTTTCTAACTTTTTATTTGTTAAATATAATTTAGAGCTGCCATAAATTTTTTTAAAGTCCTATTCCTATAGTAATAAAACTTATTCTTATCTAAATTTAAGCTCTCTTGTATTTCTTCTCTTGTCATAATATCTCTAAAATACCACTCTTCAATTATCTTTTTACTTGTAGGATCTAACTGTCCTAATACTTTAGTTATTACATCAACTTTCCAACTCTTTTCCATATCTCTTAACATATCTTCTTCTACAGTACTTGTATGATTATATTTGTTCTGATTTATTTCTCCCCATCTATTCGGTGAACCTAATCCTGGTGTTTCTATGGCTAACAACCAATATGGATAATTTCTTAAATCATTCTCTACATTCTTTTTATATTTCTCATAATTTTTTTTATTCATCATAGTTTTTAGCCCCTTTCTTTATGCCGCATACATCTTTTTCTCCACAGTTATCACAATTATAATGACACATATTACACTTATTCTTATTAACCTTTATAACTGCCATTAATACCGTTAAACTAACTATTGCCACACTACCGAATATAATTTCTACCAACCTCATACCCTCCTAACCATATATAAATAACCATTCATGTTTTCTATACTATAATCTTTTTCATAATACTTAGTAAGTCTAATTCTATGCTTAAAATCTTTATACGGTAATATAAGTGCTCTTACTTTTCCTCTCATTTTAACCATAGTAATTCTCCCTTTTAAAATATTTTTTTATTTGCACCTGTACTGCTTTCCTTTAAATATTTGTTTACAGATTTATTAGAAGTTTTAAATTGTTTTTCATTATCTTTATTTTTAATTAAATCAAACATACTAATTTGTTCTCCGAATTTAATATATCCTGATATAATCTCCATAATTAACCTCCGTTATATATCATTGTAATAATACACTAATACAGTTAAGGTGCAAGAATGTGCAATTCAATTCTTACACCTATTTAATTTTTATTTTCCACTTATCTTTTGCATACAATTATAAACATTTTTAATTACTATATTTACAGATCCATCCCCTACTCTTTTAACTTGAAACCTTGATTCATCATGATAGGATTCTTCATCTATATACAAATCTATATCTCTATCTATCTTTATTCTTATTCTTTTAAATTTTTTATCTACCCATTCCTTATCTACATCTATTTTTTCTTTTATACCCTGTTCTGCAATAAATCCTTCGTAATTTAATTTAGCATCTAAATTTTCCCCGAATATATCATTAGAAACTTCTTCTATGTCTATAGTATCTTTTTCTTTTAATAGTTTTCCTACTGTTCTTATTATTTTTTCTGATGTTGCTGCATCTTCATTCAAATTGGTTTTGGCCCACTTTTCCGTAGCTTGTACAAAATTCTTTGTAGCATCTCTTTCATTTTCTATTATGTTGCACCCTAAATATTTATTTATAAAATAATTTAATCCATATTCCTCACTAGTTTTATTTTTTTTCTGTTTATCTATAACCATTAAATTAAATTCTTGATTTTCTCTTATAGGTTTTATAAATGCACACTTTTGTATCTTTTGAGCACTGGCAGGTAATCCTGTAAACTCTGGAACTATATCTATGCCCACTTTATCCTCTACCATATCTACTACATGAATATAATTTTTAACATAATCCATTTTTAATATAGCTAGCATTGGGCCATATTCTGTTGATATAGAAACTATCATTAAATCACAGGATGATATATTATCATTACCTTTCATCAATATAAAAAGTTGTCTGGCCAGTTCCTTAGAAACATCTAGTAAATCATTTTGACCATTTAAATATTCCTGTGAAATTTCTTTTACTACATTTTTCTCTTCATTAAATTTTGCATATTTTAATTCTTCATCCTTTAGACATTTATCTATATGTTTTAATATATATTTATAACATTCATCATCCAATCTTAATTTATATTCATTTAATACTGGCTCCTCACTATTGTTGTCCAATATATGAACTACTGCCTCATTTATATTAACTTCTTTTATATATTCCATATTTAAGCTCCCTTCATATAATTTATTTGAATTGTAAATTAGTTATAAAACTTTTCAATTATATTTAACTGTGCTCTCACTTCCTTTATTAATTCTTTTACAATATCTTTTTTATTTAATTCAGCATAAGTCTGGATATTCTCTGCTAATAACTTTAAAGATTCAAAATCCTCTTTATACAACATTTATCTTCCTCTCATTAAATTGTGGTATTAAGCTTATTTAAATTTAATGAACCCTTCTCCATTTACAAATCGTAGTTCATTAGTTTGTAAAGTTGCATTAGATACAAAATAACCTTGATTTACTAAACTTAATACTATTGAACGAATTCTTTCTTCGTCACAATCATCTGGAACAACCATATTTATATTTAGTATTTTAGGCATATAAAATCTCCCTTCTATTTTTGAAACACGAACTAATCTTCTTCTAATTCCCCTGTTAATAGAACCCTCTTACCTTTGTAATCTTCTTTTATGCTTACTCTATAAAGATTTCCATAGAATCTACCAATGTTTGTACCTTCGCTTCCTGTTGAAACCTCTATAGATAAAGTTTTATCTTCTATTTTTTCTAATTTTTTTATCAATTCTTCTATTGTCATATGCTAAATCTCCTTTACAAAGTTTTTGGATTATACATTATTCTATTATTGCTTTTGCATATAAATTTTTAATGCTATATAATAATTCTTGTTTAATTTCATTTTTAGTTTTATCGTTACTTGTACCATAGTAAAGTATTTCATTATTGTATTTAAATATAATATCTACACTATCAATTACATCCGTCTCTAAAGCTTTAATAATCCAATTCATATTATCAATCATATTTGATGGTTCTTCATATTCTTTTTTTAAGTTTCTATTTTGGACTGCTTTTGTATTTTTAAAATCTATAATTTTATTTTTCAAAACATCACCTCATATAACTGCTACTTTTGAAAATTAAATTAAACCTGCACCATACAATATAAGAACGATTACCACTATTGTTAGGCTTATTCCTGCAAACTCTACACTATCAATGCCCATTTTATCTAATAATAATTTTGGTTTATACTTATTACAAGTATCATCAAATTCACAACGCTTAGAAATCTCCTTTTCACAAAAACCATTATCTATAGTTGGAATCCAAAATCGACAGTTTGAACATTGCCTTTTCATTTAATTTCTCCTTCATATAATCTTTGTAATACAACTTATTTATCTATTTTTAAAAGTCCACTCTCAATACCTTTTCTTAACAAACTCAAGTCTATGGTTCTTCTTGCTGATTCATCTACTAATTTATCAGTAATTTTAAATAATCCTATTATTTTTTCTTGGCAAATAACCTCTGCTACATCATTTTTAATACTTGAAATTTCTCCATATGTTCCATTTTTAAGGTTTGTTATTTTTGTACCTACTTCAAATTCCACACCATTCACCTTTGGCATCCAATTAGTATAAACATAAACAGTACTTTCACCATCTTCAGATAATACATACTTACCACATGTAGTACATGGGTAATCTCTTTTGTATGGTGCATATTTGCACCCATAGCATGAGTATTTCATTGACCTACCTCCTAATTTCGTTGAATTGCGTACTAACTCATACGCTTTGCTATCTCGTAAATCACATTTACTGTAACACCATTTCCAGCCTGTTTATATAACTGGCTATTACTACAAACTTTCGCTGCTTTTTCAAAATCTTCATCTGGCCAACCTTGTAATCTCCAACATTCTTTGGGAGTAAGTTTTCTTATTCGTCCTTGAATTTCTACTCCATATCTATTTGGTGCTGACACTGCCCTAACAAATATCTTATTACCTTCCCCTTTGTTAGTTGTAAGTGTTGCTGCCAATCCTTCACTATCATAAACTTGTCCATTCATACCTTTGCCACTTGGGTTTACATTTTCAACAACTTTTACGCATGGTTGCCTTCCACCACCTTGACATGTATCTAGAGATTCCACGCTACTGTTGACATCATAAGTTTGATTATATCTTCTGAAATTATTAGCATGTGCAATTCTTTTTATAGAAACACCAACCGATTGACTTGTTCCTGTGATAGGAAATATTTTTCTGGTACTTCTTTCTCTAAGATGTCCAATAATGAACACTCTTTCCCTGTTCTGTGGAACTCCGAAATCTCTTGAGTTAATAACCTGCCATTCTGCATCATACCCGATTTTGTCCATTTCAATGAGAAGTCTGGTGAAGTCAAACCCTCTGTTAATACTAAGTAAGTTTTTAACGTTCTCAATAAATAAGTACTTGGGTTTATCTTCTTTTTTTGTATCTTCATTAAGTCCTGTAACTGTGAAAAACAAACTTGAACGCTTTCCTTGGATCCCTCCCTGTTCTCCGGCAACGCTGATATCTTGGCAAGGGAACCCGAAGCACCAACAATCTGCTCTTGGAAGCTCAGTTGCTTTGACATTTCTGATATCTGTTCCAAACCATTCATCCTCCTTTGGCGAATGTATTTCTTTATAACTCATATTTGCGAATTTATCCCATTCGCAATGGCCTACACATTTATGATCTGCCATCTCCATTCCTTTTCTAAATCCTCCAACTCCTGCGAAGAAATCTATAAATGTTAAACTCATTTCATCACCTCTTTGTGTCACATAAATTTCATTTTTTCATAAATACTAACCAATGTGTTTTTGCTCTTTTATTCCCAAACAAAGGTTTATAATCTATAACTTTTAATATATCTTTTATTTTTATTTGCTCTTCATTCCATTTAAAAATTAGTACTCCATATTTATCTAATACCCTCATACACTCATTAAATCCTTGTTTTATATCTATTGGCCAATCATTATTTAACTTTCCGTATTTCTTGGCCAACCATGAATTTTCTCCCGCCTTTATTAAATGTGGTGGATCAAAAACTACTAATTTAAAAGTATTATCTTCAAAAGGTATATTTCTAAAGTCTCCTATAATATCTGGATTAACTATTAATTTACGGCCATCACATAATTCATCTTCTAACTCTCTATTATCCATGTAAATAGTATTTTCATTTTCTTTATCAAACCAAAACATTTTGCTTCCACAACAAGCATCTAATATAAGTTTTTCCAATTATATCACCCCATTTACTTGCACAATAATTTCATATTCCGACTATTAAATATATACATCAAAGTGGTTGTCTATATCATCTTCACATTCAACATCAATTATTATTGGTGTTTCATTATATAAAATATTTGCTATTAATAACTCCACCTTTGACATATTTCCAAGCTTTAATGTTTTCTTTAAATCTTTTCCTTCCATACAAACAGTACCTAACCAACCTTTTTTATAGTCTTCTTCATCTTCATTTTTAGATTTTCTGTGAATAGTAAACTCAATATAATTTTCTTCATTTCTATATGAGTATCCACTAGGTTTTTCTTTTGCCATTTTAAATGTTAACCACTTATATTCTTCATCTTCATTAACATCTATCCAAAAATCCTCTAATTGATATTTTTCTGCTTCATCTGTACTTTCACACATATACTCTCTGTATTCTTCAAATATTTCTGATAGTTTAATATTTTCTCTCTTTACTACTAAAAGTTCATTAAATGTTTTTTGGATTTTATTTGCAATGTCATCTCTGCACACATCTTCTGTAATTTGCTTAATCTTCTCAGCAATAAATCCGTTATATCCTGTAAATCCAATATCTTTAACAACCTCAGAAACTTGTTTCTCTACCTTATCCTCTATTTGTCTTTTTAAGCTGTAGCTGTCTAATGCTCCTTCAATTCCTTTAGTTATAGCTTTTTCTATATTCTCTTCTAATAATTTTTCAATTTGCTTATTTTCTTCCATTTCCTTTAGCTTGTTATTAACAATAGCATTTATATCTATATTCATAATTTTTACCTCACTTTTATTTATTTTTAACCAATCCTAGTGGTACTCATTGTACACTTGAAAAAATATTCTTTTTTTAAAAATCCAACCTCTATTAACTAATTTCTTATTATGTTTTTTAACCTCTTCTTCTAAATCTATATCCTTGTTTTTTACTTGTGTATCTAACATTCCAATGCACACCTGCATTATGTCTAATATCTCCTCTGTAGTGTTTTCTTTATCCTTGTTTAAAATTGCTTGTCTTACTTCCTTAAACTCTTCCTGCAATTTTAATAGTTCTTCTGGTAATGTTTCTTCTTTATCTAAAATCATTAAATGCATCCTAGTTCTCCTTGTTTTTCTTCTATAGTGTATTTAAACCCATTCATCCTAATTGGTAGTGTTATATAAGTTATGTCCTCTGATCTAAATATTAAAGGTGTTATAGGACTTTCAGCATAGATTTCATAATGTTCAATATTTATATTCTTTAATAACTCTTTATTTATAAATATCAAGTCATCATTCGCCTTAAATATTTGCATTTTATCGCTCTTTTCATATACAAAAGGTAACATTGTGGCTTTTATTTTATTAGACATATCAAAGTCTTTTAATATGTCTAAACTGTCCCATTTATCTATCTCACCATCTCTAATGCCAAATCCAGTTTTTAAATTTTGAAAGGTTTGCTTTCTTATTATTTTTTTATAACTACTAAATTTATTAGGTATCTTAAATCCTGTGTACCCATCTACTACTACGAAAAACTTTCTACATGGAATAAATACAAAAGTGTTCTTTAAAGCATTTTTAACCCATCTTTCAAATAGTTTTATATCTGTCATGATTATTTATCCCCCTCAATCATTTTTTGGCCTACATTACCTAACATTTTTTTAATTGATGTAGGTATTTGTTTTTCTTCTTTTTTTCTTATTACTGTTTGTTTATAACTTCTCATAAAGTTTGACCCTATAACAGTTTCTATCCCATTAATGCTCTCTTGGCTCCAATTATGGAGTATATTATGACTTCCTATAGCTTCTTGTATCCTAGAAGGCAACTTATTAAACTCTTCCTCTGCATTATAAGCAGAGTTTTTTATAGCTTTCCTAACTAGCCCCCATGCTTCAATTTCTGTCATTTCTGATTTTCCACCACTAGTTATATAATTTATAGCTTCTATCACTTCCGCCACACTTGGTGGAAACTTATTAGTTGCTATAATCTTTTTAATAGCTATTTGTACTACGTTATATGGATAGTCCTCTAACATAGTGCTCCATAAATTGACCATAGTCTTAGCATCCGTAGGCTTTAAATCTCTAGCCCATTGCGGGTATGCTGCTTTTATAATACTTAATATTTTTATAGTTTCTTCTGGTATCATTTACATACCCCCATTCAACATATTTAAAAATGGGTTGTTTGAATCTGTATTACTTGAATTTTGTTTTATAGAATTACTTTCTTTTAATGGGAATACACCTTTCCAACTATTCATTATTGATTGTTCTAATATCTTAATTTTTATATCATCGCTATTAGATAATTTATTTAAGTTTTTAAGCATTAAGTCTAATGCATTATTTGTCATTTTAGATTTTATTAAAGTTCTCATTTTTATAAATTCTAATATAGTATTTTTTAATTCTTCATTTTCTGTATATTCATCAATTATTGTATTGTAAGTTTTCTTAGTACCTTCTTTCTTACTTCCTTTCTTTTCTTTCTTTTTCTCTAACTCTGTATCTTTCTCTATATCTAACTCTATATCTATCTCTTTCTCTAACTCTATCTCTGGTGGATGTTCGTCGGACATTTGTCCTTTTGGCAATAAGTTTTGCTTTTCAGCTTCTATTTTCTTTCTATATGCTCTTTTTCTATCCCCCTCCGAACTACTCTTACCTATAAAGTTTTGTATATCTAGCATATAAATAGCTCCATTGTCCAATATTTCTATTAATCCTAACTCTATAAATACTTTTATAGCCTTTTCTACTACTGCAATGTTGTGCCCTGTTACTGTAGCAACCATCTTAGGGTTGTATGGAATATGTTCCTTAAACATTAACCTTCCTTCATTTTTAAGTGATTTTAAATATAGTTTCATTAATATATCTGAGTATAAATACCCATTATCCATGCTTTGTAGAATCTTTATATCTTCTGTATCATAAAAATTTTCTTTAATTCTTAGATAATAATATTTTTTATTGTCACTCAAGGTTTGACCCTCCTTTTGTAGAAATTCTATTATGTCTTTTAAGCTTTACAAATACTTCAATTTCTTATAAACTGTATTTAACGAATTTTTATTTAAGTTTTTTGGTGGCTTAGGCCATCTCTTTTTTTATTTCAAAATATCCTATAGTATGAAAATTTGCATTTACATGACCTTTGGTTTTTTCTTCATTACTAAACGAAAACCATATACTACTTGGTGAACTGCAAACATATGGAGCAACACATCTAACCATTTCTTTATAAGATATTTCCTTTATGTTCTTTTCAAAAGTTTCATTAGCATATCCAATATCCTTAAATTTAATTATCATTTTTACACCTTCTTTCTATGCACATTTTTTAAATATATCTGCACTTCTTATTGCAATGTCTAAAACATAATCTAAGCTTGTACACTTTCTAAAGCTAACTCTGTTAAACTTAATATCATCTGTTGTAATTTCAGCAACTATTGCAAATTCTTCTTTTGTTAAATTGATTCCCCTTTCTTCTAGTAATTTTTTTAACATTTCTATTCCTCCTTTTACTGTTTGTCCCCCTTGTGGTAAAATTTTGTTGAAGGGGGTGTTATTATGCAAAGAACTCCAGTTGATTCAAGTAATTTATCTTCCGTTGGATATGGAAATTCCACATTAGAAATTGAATTTCACTCTGGCAAAGTGTATAGGTACCTACATGTACCTGAAATTGTTTATTCTGCTTTAATGTCTGCACCATCAAAGGGTAGCTATTTTTATACTTATATTAAAGACAAATATCCATTCCAACCATTAAATTAATCTATAATTTTTTTAGTTGCTCTTGAGCTAGTACCTCAGGAGCTTATTTAACTATCTCAACGTTCTCAAATATCCAATTTAAAGCAATTCTTTTTAAATCATTATGATTTAAAATACTTTTGTTCTTTTCTAAATTTATTTCTTCTAAAAATTTGTAGTCCTCTTCATCAAGGAATTGAACTGTTATACAAAATATTTCTTGGTCATACAAGAACCTAAAAATATCTATATCTATATAAAGCAATGTTCCTGTAGAAACATTTAAATTTAAATCTGTTGTTTTTATTTTTTATTCATTTGTAATCCCCCTAAAAACTTATTTGATTATTAGCATTTATTATCTGGTCCTCAAGATATATAGGAACTGCATAATTTCCTAATATCTCTTTTGCGGTTTCTAATTGCATCCTTTTTATTGCTTCATACCTGTTAACTCCGAATTGCCTTTTTAACTGACCTTGTATGTCTGCATACACTTTACCTCTTAAAGAATTATCCTTATATGCAGGTGTTCTATAACCTCCTAGAACTCTTATACCTGTTTTTCTAACTAGTCCTTGTAGTTCTTTGCACTCTATGTTAAACAAAGGCATATTCTCTTCTAAGTTGTTTACTTTTTCTTCTATTTGTTGTGTTTTCTTATCTAGTACAAAAACCGCTTTAAGTTCTGGAGATAGTCTATTGTATAAATCTATTTCTTTAACTCTAAAGTAAGTTTCCTCTAAATTGTCAAACTGCTCCCACGCTTTATCGGTATCGAGGATTTTGCAATGGCGATTTGCTCCTCGTTCTGTCCACAACATTAAAGAGTTTAATTTTAACGAAGTATCTTTAAGATACTCTCTTTTAAATTGTTTAAGTTCTTCACCTTGTAATTTAAAATAATGTTTACCCTCTTGAAATTTATCTTGGTTTCTAGAGAATCCCTGTCTTATTCTAACTTCATCAACCTCATAAACTTCTCCAAGTTGCTCTGTTGTTAAAACTCTTTGACCTTTAATTTCTACTGGCTTTATTTCTGTTATTACAGGTTGTCCATTTTTTATGTTCAAAATCGCCTTCTCCATTCTTTTACCTCCTGTATAATTTAAGTTAATCACTTTACATCTGTGAGTAGATATCTTTATAATCTAGATATTAATTTTTCTAACTGCTTTGGGGTTAAAATTTGATTTAGAACAGTTAGTACTGCTTCAGCTTGACTTTCTTCTAACTTTCTTTTTCCTTCCTCTGTGGTAGGATAGTTTACAACAACTTTAAATCCCATTTTTACACACCTTTTTTAATACTTACTTCATTATATGAAATAAGGTTTGTACTAGTTTTAATATTGTACAATTTATTAAATGCACACCTTAATATCTCTTTCTTCTCTTTATCTTGGAATTTTTTTAAAAGATTATGGATTTGCTCTTCCAAATTTTTGCACCGCCCTTTCTAAATTTATCTTATAAGCAATCATCACATCTTCGTGAGTGCAATTATAAGCTTGTACCATCTTTAGCATTACAATTTGACTTGGATTCCTTATAGCTATTTCATACTTATTTAATGTGCCAGGCTTAATTCCTAATCTTTTAGCACTTTCTTTAACTGTTAAACCTGCTCTTTCCCTTAGCTGTCTGAATGTCATCCCCTCACCTCCTGTGATTATAATATCACGTATCGTGAGTGAATTAAAACTTTAAATTCATTTATATTTTGATTAAATTACTAATTTATAGCAATTTAGCGAAAGTATGTTCTGAAATCACACCATTAATATCATTTTCTTTTATTTTCTCACAATACTATTGATTTACTCACATATTGTGATATAATATTCAAGAAAGGAGCGTTAAAATGAGCAATTTAGGTGAAAGATTAAAAGAATTAAGAAACGAGGCTAAATTATCTCAAAAAGATTTAGCTAAAAAATTAGGATTATCATCTTCAACTGTAGGGATGATTGAGAGTGGGAAACGTGAAGGAAACAAAGAAACTATACAGAAAATCGCGAATTTTTTTGGGGTTAGTATAGATTACTTATATGGAAATGATGTTGAAGAAATTACTAAAACAGAAAGCTTAATTGATAACTTTTTAGATAGATTAATTCAAGAAGGTATAATACAAGATCCTAACAATATAGATAGTACAACAGAAGATATGATATTAAATGCTATAAAGGCAGAAATAGCTTTAAAATTAAAAAAGAAAAACAGCTAA

Protein sequences of DBSCAN-SWA_6

>NC_017297|3378914:3462532|3442706_3443036_-|WP_012100895.1|head,tail|DBSCAN-SWA
MDLNELKEYIKLEEDEGEKITIPSLLLAAKAYIKGATGLTEDMIKDNEILELYKLCIKILVSHWNENRAIETTGPNFHKLSFGVDSILLQLEAEYLKIKRGATDGSGQT
>NC_017297|3378914:3462532|3415060_3415258_-|WP_003405999.1|bacteriocin|DBSCAN-SWA
MKKLVKNKKSELVSLEAYSCNCGYCYANCTCSCGYDPQSSVNRSRGSNADNARYVSRGNSYDSHD
>NC_017297|3378914:3462532|3442399_3442726_-|WP_012100894.1|head|DBSCAN-SWA
MDPGKLNKRIKFIIIENGTDDEGYPIKGEKTIRECWASVRGLRGREFYNAAAVQSEQDKIFNCRYFKGLDTSLQIKYKNKFYDITSINDLNERHVEYEIHAKEVKASG
>NC_017297|3378914:3462532|3387094_3387835_-|WP_003405923.1|DBSCAN-SWA
MECYREFAHIYDELINEDIDYEKWAKTITNICDEFNLCKIDYLDLACGTGNLTLQVSPYFKNVWAVDLSYDMLTEAENKFRENNIKGKLVCQNICDLKLNKTFNLITCCLDGINYILDKKSLNNLFKNVYNHLKEDGLFIFDINSYYKLNNILGNNLFSYDDDEITYIWRNSTENNITNMDITFFIREDENNYIRFDEEHKERAYKEEEIEEIILNNGFKILRTLDNYENKKIQEKTERIVYILTK
>NC_017297|3378914:3462532|3381169_3382069_-|WP_012100842.1|DBSCAN-SWA
MLLFTMVYNNEREDLIDKLVKLKECFQSRNVVIGLSENIEDKTHFIKIYCEEKFLNKKVIDSINNELVNILYGITADRFIKVELNKFITDDYFFLKQEEIKELSEKISDVLKDRDKRYIEDSIYCLNKKNEIIKKIKKCIDENNEINIDGFLTFRCRELFKDIKGIIDKIVEKYMVDKEYNEFIKLLKYFVEIEESKLDKLNILIDPTGKYTLKDSEGNDLTEEVYIEVSDVKYVENISVDDMLISWLITNVPKEINIYNIENCTNKELINTIKNVFEERVNIYNHDKPIKLKHTYNKL
>NC_017297|3378914:3462532|3430873_3430996_-|WP_012100882.1|DBSCAN-SWA
MLSYIKEYFLMGLYMEEDLDIFVQAKWITIEEKENIIKTQ
>NC_017297|3378914:3462532|3422845_3423319_-|WP_012100872.1|DBSCAN-SWA
MKKLISILISGILTLGLVACGSTQTNNEENKNNDKPKQEQIKKESMKEESQEELNKKIKDSAVKADFVKINGHEKELKGKSYYIEGEVTFIDNTNSVLPKFTVKTKEGEGYGMYDIENFGKAEVKEGDKVKVYGKLNENKSETGAPQISGNVIEKQK
>NC_017297|3378914:3462532|3454625_3454988_-|WP_012100918.1|DBSCAN-SWA
MKYSCYGCKYAPYKRDYPCTTCGKYVLSEDGESTVYVYTNWMPKVNGVEFEVGTKITNLKNGTYGEISSIKNDVAEVICQEKIIGLFKITDKLVDESARRTIDLSLLRKGIESGLLKIDK
>NC_017297|3378914:3462532|3429318_3430221_-|WP_012100880.1|DBSCAN-SWA
MNIRNANLSFGSMSYGNNPQELDLHHAEASVCSVLDVHSWHKGNGWAGIGYHYFVRKNGEIWKGRPDSAIGAHVAGHNTNTLGICAEGSYMSEDMPQAQKNAIIELCKYLCNKYGINKIYGHREVGSSNCPGTKYPLAEIKNAVLNGGSSNNPGPVVNDNVRDKVGIITGSGVNVRLDPNGKILGSVNKGDKVKLYRLEGDWYHCYSLYSGYNRCYIYKNYVSIQGSSNGSSSGTNLDGKTGVINTPSGVNVRADKSTSSKILGTLSNGSKVQLYRKEGDWMHIYYPKQGGYVYAKYIRY
>NC_017297|3378914:3462532|3459871_3460054_-|WP_012100927.1|DBSCAN-SWA
MLKKLLEERGINLTKEEFAIVAEITTDDIKFNRVSFRKCTSLDYVLDIAIRSADIFKKCA
>NC_017297|3378914:3462532|3440775_3441063_-|WP_012100890.1|DBSCAN-SWA
MTITITLLIDGKEKIFNAPFISTRRLKETLALSEKIYNGITIETIDEVAEHLVEIYGNQFTIDELYDGFPANEFANKAIEDMQRVLGNFEDKIKN
>NC_017297|3378914:3462532|3449618_3449960_-|WP_012100904.1|DBSCAN-SWA
MLDYRIITKEEYKKIRLNSVSASSICEGMIKEIDKNWDRLRKGYDFIIAVGLGDKPMFYSVEYFNEHILDSKGKSNKTEKQLKIASSLAAIVSYKFALEFEESLNKVKEMLDK
>NC_017297|3378914:3462532|3455020_3456037_-|WP_012100919.1|DBSCAN-SWA
MSLTFIDFFAGVGGFRKGMEMADHKCVGHCEWDKFANMSYKEIHSPKEDEWFGTDIRNVKATELPRADCWCFGFPCQDISVAGEQGGIQGKRSSLFFTVTGLNEDTKKEDKPKYLFIENVKNLLSINRGFDFTRLLIEMDKIGYDAEWQVINSRDFGVPQNRERVFIIGHLRERSTRKIFPITGTSQSVGVSIKRIAHANNFRRYNQTYDVNSSVESLDTCQGGGRQPCVKVVENVNPSGKGMNGQVYDSEGLAATLTTNKGEGNKIFVRAVSAPNRYGVEIQGRIRKLTPKECWRLQGWPDEDFEKAAKVCSNSQLYKQAGNGVTVNVIYEIAKRMS
>NC_017297|3378914:3462532|3421500_3421746_+|WP_012100868.1|DBSCAN-SWA
MKTKKLTLLSLVTILIFLLTLFTGCNNKKEETENLTKVKLNEVVRSVFYAPMYVAINEGIFKEEGIEIDLSTGQGADKTLS
>NC_017297|3378914:3462532|3422235_3422472_+|WP_012100870.1|DBSCAN-SWA
MIKIFREHKGIRQEDLASRLGITQPYLSKLENNSIYGINVNVDLIESLAMELNICPIAVFLYFLNVKISCPFYLKKTE
>NC_017297|3378914:3462532|3400260_3400962_-|WP_003357563.1|DBSCAN-SWA
MMDNLMLNNKIYLEGTVVEDLEFSHEMYGEGFYNFKMEVSRLSDVSDILNITVSERLLADMELKVGMDIIVEGQLRSYNKFVDGSNRLILTVFARNIEYCIERSKNPNEIFLDGYICKEPIYRTTPFGREIADLLLAVNRPYNKSDYIPNISWGRNARFCKTLQVGDNIRVWGRLQSRYYQKRISEDKTITKVAYEVSISKMERVGDEQAGDNDYEESYEEKDFMDNIKEKHA
>NC_017297|3378914:3462532|3443227_3444355_-|WP_012100897.1|capsid|DBSCAN-SWA
MNRYQLEQMLAGIGQDLKANTEKLTTMYADAKTTLEARNEQKNTVKDLEERFAGIKAQIEEMDRQAEEKIKNKNITGDTEKEKVVNAKAELIRATMANKPVGVEIKAALGDGNSSGGEKILPRTMTNELLHEPFVKNPLRDVSVFTNITNLEVPRIDFTLDDDEFIKDTETAKELEVKTPTVQFGRHKFKVFSSLSETILRGTNTNLVQTVDAALESGIAAKEKKVAFTKTPKSGEEHMSFYSPQNNIKIIEGENLYKAIKGALADLEDDYAENATISMTRKDYYDIIETLANGNATLYGAQPEQVLGAPVKFCDKAVDPVIGDFRYSHFNYDLDMLYDRDKNVRTGMEDFVLTAWIDHQIKLKSAFRIAKVKTP
>NC_017297|3378914:3462532|3396711_3397467_+|WP_012100853.1|DBSCAN-SWA
MVRVILNGSNGKMGKVICDLAENYSNLEIVAGIDKGEATSSFPVFTDINKCNIEADVILDFSRPEALNDLLNFATSKNMPIIICTTGFSENQIKLIEETAKKIPVFRSANMSIGINIVNNILKNISAFMYKNFDIEIIEKHHNQKVDAPSGTAILLGDTIRDSIKEDTKYTYGREGSSKRTHDEIGMHAIRGGTIVGEHDVIFAGSGETIEIKHTALSREVFAVGALNACLFMSGKEAGLYNMDKVIQAAL
>NC_017297|3378914:3462532|3441786_3442029_+|WP_154018643.1|DBSCAN-SWA
MHLLLIISLYLLLIFLYSLCSIYLLAYKILYQSLCHPQSTPLARYNRRKLYMFLLSPYKFENSLECLEALKHLLLIYLCS
>NC_017297|3378914:3462532|3406340_3408986_-|WP_012100860.1|tRNA|DBSCAN-SWA
MSETREMAKTYDPKEFEERLYKNWEEKSYFTPEVDENKKPYTIVLPPPNITGKLHLGHALDDTLQDILMRTKRMQGYSTLWLPGQDHASIATEVKVENELLKEGIVKKEIGREAFLEKVWEWTDEYRNKIRNQIKKLGCSLDFTRERFTMDEQLDKAVKHFFVKLYNEGLIYQGNRITNWCPKCKTALSDAEIEYSEHEGHFWHVKYPVVGSDEYLEIATTRPETMLGDTAVAVNPKDERYAHLVGKTLMLPLVNREIPIVADDYVDMEFGTGAVKITPAHDPNDYQVGKRHNLPEINVMFDDGRINYKETRYHEMDRYEARKAIVEDLKNEGFLVKIKEHNHNVSCHDRCNTVIEPIISKQWFVKMEELAKPAIDVVKNKKVKFVPERFDKTYFNWMENIQDWCISRQLWWGHRIPVWYCKDCGEVIVVTEEPKKCPKCNSEKLQQDNDVLDTWFSSALWPFSTLGWPDKTPDLKYFYPNNTLVTGYDIIFFWVARMVFSGLYCMDDIPFDTVLIHGIVRDSEGKKMSKSLGNGVDPIEVIDEYGADALRFTLVTGNAPGNDIRYYPERVEAARNFANKIWNASRFVLMNLDKDLMDKYKDNKNYTIADKWILSRLNTVVKEVTENIEKFELGIASQKIYDFIWGEFCDWYIELVKPVLYGEDEQSKGIAFNVLHKVLETSLQLLHPIMPFITEEIYTHLYTEYESIVISKWPEYDEILKDEKSEKDMEYIIEAIKSIRNVRTEMNVPPSRKAKLMIYLTEKEAERSFKEGEVYFQKLASASEVSFLENKETSDKNVSVVTRGAEIFIPLLELVDIEKELERLNKEKEKLEKEIDRVEKKLANEKFVSKAPESVVNEEREKGEKYKAMLKSVRESLESLK
>NC_017297|3378914:3462532|3450426_3450972_-|WP_012100906.1|integrase|DBSCAN-SWA
MNFVEPIRDTQKVRDIQEYLKRTNDRDYILFITGVYTGLRISDILRLKIKDVKNKRFIYIREKKTSKQNIIEINKFLEKEYKWYCTDKELDEYLVKSREGINKALSRVRAYEIIKKVGEDFGVDNLGTHTLRKTFGYHYYKQSKDVATLMKMFNHSDPSITLKYIGIIQDQMNKARRNFTI
>NC_017297|3378914:3462532|3457349_3457637_-|WP_012100922.1|DBSCAN-SWA
MHLMILDKEETLPEELLKLQEEFKEVRQAILNKDKENTTEEILDIMQVCIGMLDTQVKNKDIDLEEEVKKHNKKLVNRGWIFKKRIFFQVYNEYH
>NC_017297|3378914:3462532|3410099_3411344_-|WP_012100862.1|DBSCAN-SWA
MAFKSPIIIIDDGVNSDLCNLGELKSDIEVTSDLEIKENLDCYNEFTYHGSTCAAIIKKYLPNAELGSIKILSNFKGTRYQLVKAIKWCVENNIKLINLSLGTVNFQDFKLLYSCMEYAYKKGLIIIAAYNNKRIYTCPASFDNVIGVKCDTTGTLKRSEYIYNTYSLDGIEVIANAKHNIIDNSGMVYTTSICNSYATPVVTALVYELIEKYPDITINEIKTYLRNRSVNNNNSIDLIKRNHKIQKNVDVPVMIFYDFTGYYGATISKLFCELFRANGYYAIAIVDSILKSSKHEGIISFRENYNNIEGINSTVLKDVYSVFNCDILISCIDKTNLQKELVENLNSFTDMEVDIKILIIKNFTIDIKNIIEKNSESEILIFCYTENVQAVKEKNYRVFYDVYELFMHVLRILT
>NC_017297|3378914:3462532|3404206_3404467_+|WP_003357396.1|DBSCAN-SWA
MYTYSPIGVCSKKITFDILNNKVVKVNFLGGCDGNLKGLSSLIEGMDIDDAIKRLQGITCGSKNTSCPDQLSKALQEAKKQNKESI
>NC_017297|3378914:3462532|3453839_3454025_-|WP_012100915.1|DBSCAN-SWA
MTIEELIKKLEKIEDKTLSIEVSTGSEGTNIGRFYGNLYRVSIKEDYKGKRVLLTGELEED
>NC_017297|3378914:3462532|3458688_3459525_-|WP_012100925.1|DBSCAN-SWA
MSDNKKYYYLRIKENFYDTEDIKILQSMDNGYLYSDILMKLYLKSLKNEGRLMFKEHIPYNPKMVATVTGHNIAVVEKAIKVFIELGLIEILDNGAIYMLDIQNFIGKSSSEGDRKRAYRKKIEAEKQNLLPKGQMSDEHPPEIELEKEIDIELDIEKDTELEKKKEKKGSKKEGTKKTYNTIIDEYTENEELKNTILEFIKMRTLIKSKMTNNALDLMLKNLNKLSNSDDIKIKILEQSIMNSWKGVFPLKESNSIKQNSSNTDSNNPFLNMLNGGM
>NC_017297|3378914:3462532|3452368_3453418_-|WP_012100912.1|DBSCAN-SWA
MEYIKEVNINEAVVHILDNNSEEPVLNEYKLRLDDECYKYILKHIDKCLKDEELKYAKFNEEKNVVKEISQEYLNGQNDLLDVSKELARQLFILMKGNDNISSCDLMIVSISTEYGPMLAILKMDYVKNYIHVVDMVEDKVGIDIVPEFTGLPASAQKIQKCAFIKPIRENQEFNLMVIDKQKKNKTSEEYGLNYFINKYLGCNIIENERDATKNFVQATEKWAKTNLNEDAATSEKIIRTVGKLLKEKDTIDIEEVSNDIFGENLDAKLNYEGFIAEQGIKEKIDVDKEWVDKKFKRIRIKIDRDIDLYIDEESYHDESRFQVKRVGDGSVNIVIKNVYNCMQKISGK
>NC_017297|3378914:3462532|3428428_3429166_-|WP_012100879.1|DBSCAN-SWA
MSYTLFIDESGNISKNNGERYFCIGGYLIEKGNKNHAYKMKKIVSNVQKNREKYFNINARKNNKNEVKFSNLNVDGKNYVYENFQKLKGTYVSIVVDKFNCTRLTNHKYNDYYNYLVYLLVKYVFDIRKYAKGYDFKELKIIYDNRSMKIEANNNLQVYLLKKLKIERKHNKFNCNFNIKEADSKVNYGVMISDFIAGLCWARYNYGIQKYGNSIEIDYLSKFPYKDFAKEIHCKEIEKKVLTHL
>NC_017297|3378914:3462532|3409006_3409513_-|WP_012100861.1|DBSCAN-SWA
MTMIIRAVSPEDYKEINEIRCMIGVRENILGRISERLEQSKEFIQSLGSNDHLLVAEIKEEDKNKVVGVIGLNINSNPRTKHTASLGMMVHKAYQGNGIGKKLMSEILDLADNWLMLVRIELGVFTDNEKAIKLYEKFGFEIEGTKKYAAIKNGRYADEYIMARYKNI
>NC_017297|3378914:3462532|3378914_3380822_-|WP_012100841.1|tRNA|DBSCAN-SWA
MIKITLKDGKVMEIEEGIKISDIAMKISPALYKKALAAKIDGETVDLMTELHKDSSLEILTFEDEMGKWALRHTGAHILAQAVKRLYPEVKLAIGPAIDTGFYYDFEADFTFTPEMLEKIEAEIKKIIKENHKLERFELPREEAINLMKEKNEDYKVELIEDLPEGEVISFYKQGDFTDLCAGPHVPSTGKVKSVKLLSLAGAYWRGDEKNKMLQRIYGTAFTKKSELDEYLNMIEEAKKRDHRKLGKELDLFSIHEEGPGFPFFHPKGMIVRNILESFWREKHTKAGYQEIRTPLILNEALWHQSGHWDHYKENMYFTNIDDGDYAIKPMNCPGGILVYKSSMHSYRDLPLRLSELGIVHRHELSGALHGLMRVRCFTQDDAHLYMTKEQIKEEVIGIIKLIDEFYKLFGFEYFVELSTRPEDSMGSDEDWEIATNGLREALDSIGKEYRVNEGDGAFYGPKIDFHLKDCIGRTWQCGTIQLDFQMPERFDLSYIGADGEKHRPVMVHRTIYGSVERFIGILIEQYAGAFPTWLAPVQVKLMNITDSQYDYLKKVEETLKENNIRVEIDTRNEKIGYKIREAQLQKVPYMLILGDKEVEAGKVAVRSRKDGDLGAISLEEFIEKIKNEIKNKTN
>NC_017297|3378914:3462532|3456569_3457313_-|WP_012100921.1|DBSCAN-SWA
MNIDINAIVNNKLKEMEENKQIEKLLEENIEKAITKGIEGALDSYSLKRQIEDKVEKQVSEVVKDIGFTGYNGFIAEKIKQITEDVCRDDIANKIQKTFNELLVVKRENIKLSEIFEEYREYMCESTDEAEKYQLEDFWIDVNEDEEYKWLTFKMAKEKPSGYSYRNEENYIEFTIHRKSKNEDEEDYKKGWLGTVCMEGKDLKKTLKLGNMSKVELLIANILYNETPIIIDVECEDDIDNHFDVYI
>NC_017297|3378914:3462532|3431397_3433062_-|WP_012100884.1|DBSCAN-SWA
MEKSFVFNSVNGDRRYKAEDFREYFASFISNGVFPNPSNNLQVIANNDMTITIKAGKGWINGAIYINTDDYILNIDVADGVLNRIDKVVLRMDTAERKIYSYVKKGQFASSPTAQTLQRDADAYEIALADVAVNKGAISITQANITDLRLDKNLCGIVHGTVDQIDVTTLFNQYSTRFKIKSEEFEKEFEDWLKTLKDVLGEDTAGNLLNLITKNTESINNIKSDLADITKDSYPIVEATGTNAYISSNNKITSLEKGTRFTLFIGNNATGNCTININNYGAKNIKDPFGKIVNNLKSNIPYNLCYNGVDFILQGKGGGGNLKPNQALKGYSFTNDDGPQVGSGDPNLIPKNILNGKNIFGVTGTAKPAPAPLPIPPEGFTRYLVGVTDKYVLAYTNKTSGNINNPILYYRDSGVLYAHYNKNDTYDTYMLFLPDGFWHSKVNDHTLYKYSYEDILLQTMDYNTGSVYNNLFRKTNGVGNYNYFYTDKMSFNANNFVLESVWYTDLGIPIMNSEKKQCYLYSPSKTLIPLRGKEGPIESETKKMNTYELPLEIY
>NC_017297|3378914:3462532|3444347_3445148_-|WP_012100898.1|protease|DBSCAN-SWA
MNKVLQFKNKNKQTGKEEVVGTMEIKNQTEEKAELYFYGDICSSTWGCWEEEDKCPQDVSNFLKEIDNNKELDIYINSGGGSVFAGLAIYHQLKRHNGFKTVHVDGLAASITSVIALVGDKVVIPAPAQFMIHKPWTIALGNANEFRKQANDLDIAEESILKIYEANLNEGVNIETIKQLMADETWMTGEKAAEYFNIEVEETQELVACTSQYFNEYKNMPKNLFAKSIKPKEPENKDNFIKDEEIESLIERVNNTLKFEEERINE
>NC_017297|3378914:3462532|3402652_3403180_+|WP_012100858.1|DBSCAN-SWA
MFDDALELAENKLLILYVFNRLDLSISNNKITEIILENNLINYFTLQQYLSELASSGFIKNTDQHKIMITEKGIRVLSMFIDRINEDKIESINNYLDSKLNSIKKEVNIMADYTLENKDTFLVSLKATENNFLLMDIKLSVNSNKEAKEICSKWKENSSAMYTKILNILRSTNEN
>NC_017297|3378914:3462532|3460117_3460324_+|WP_012100928.1|DBSCAN-SWA
MQRTPVDSSNLSSVGYGNSTLEIEFHSGKVYRYLHVPEIVYSALMSAPSKGSYFYTYIKDKYPFQPLN
>NC_017297|3378914:3462532|3413564_3414971_-|WP_012100865.1|DBSCAN-SWA
MKQNAFFHLFKTRNCCYIYDVNTNLFLKVPKETYSALENYNGDLEALKDDSVILNLKEKGYLSSNRAEEIEHSLTDALESILDNSLNTLTLQITQECNLRCSYCVYSGSYLNRSHSHKIMSIDTAKKGIDFIINHSKNSPTVNFAFYGGEPLLRFNFIKECVAYAKEKGEGKKITFNMTINGTLLTDEIIKFMKDNEVSLLISMDGPKEIHDKNRVFSNGMGSFDKIMNNVNKIKVKFPEYVEKNVGFNIVMDGQNDFSCINNFFANYDTVKDSRVNATDVSTLGALEEKAISEDFIQDEKYERFKILLHKLGKLDEKYISKLLLSQFEHINHTLNVKREANEKVPKKMHPGGPCIPGLNRLFMTVDGKFCPCERVNEESEAMNIGNVNTGFEIEKIKKLINVGEMTKQKCKNCWAFRYCYLCAAFADDMNELSGVKRAKFCNDVKRNTEEMFKVYCTMMEFGYKFEE
>NC_017297|3378914:3462532|3401039_3401537_-|WP_012100856.1|DBSCAN-SWA
MKKICIYSEDESFVRHIHNMIKILDLDLHYSRENTLANSEYIVINRDINFEYDGIDCEYCFINMDLFKNKNVDIKGVVITYGLGNKNTITLSSLEQENIGIVYCIQRYISIYNENIIEPQEMPLNIYYEDESCLYAYMVIITIALIQGANISNIESKIINSTNKF
>NC_017297|3378914:3462532|3426920_3427322_-|WP_012100876.1|DBSCAN-SWA
MIYGYCRTANDNKKSIENQIGWIKSKGVNEKDIYIDIGSALENGAELNKLLDSIQEGDTIFSKDINRITRSHKGLEKIIEFAKTKRVKFVLGDKIIDGINGVDIGVEAISAMISTLKEYEESIENSYIDNMEE
>NC_017297|3378914:3462532|3460632_3461391_-|WP_012100930.1|DBSCAN-SWA
MEKAILNIKNGQPVITEIKPVEIKGQRVLTTEQLGEVYEVDEVRIRQGFSRNQDKFQEGKHYFKLQGEELKQFKREYLKDTSLKLNSLMLWTERGANRHCKILDTDKAWEQFDNLEETYFRVKEIDLYNRLSPELKAVFVLDKKTQQIEEKVNNLEENMPLFNIECKELQGLVRKTGIRVLGGYRTPAYKDNSLRGKVYADIQGQLKRQFGVNRYEAIKRMQLETAKEILGNYAVPIYLEDQIINANNQISF
>NC_017297|3378914:3462532|3424421_3426047_-|WP_012100875.1|DBSCAN-SWA
MLSLLTSTALIGGSTIAAELFGVKLKNKKNKIDDLANGKLFTKKDLENILGDYLQLSKNIKLEEKIAFEGTVIIAPTGGGKTTSFFIPNLLNPNLKGSIVAYDPKGELYEKTSWFQKNICGRDIVVFAPLEPSISCKYNLLEQCKDTTEVLQLASTLITNGSLAIELQTGKKTGGTEWDNMATPLFSAALLYCKAQGLPVSTIENAFRLIIEKSLQELDTLFSNSTEDCRTQWDIFNSVGDADRTIGSIKITLTTALKIFGDKKICKVLSGTSTFNPAHLRKKSTCIYIISEERRSSYVSPVMASFFSQLFDKVLDSYNKNSLPVYFFLDEFANLGMLNNMSVNCATVRSREISLNICLQSISQLEQIYGKDNALSILNNLKTKIAFSGLSDLKTLDYISQLCGNTQIQVCNTSITKDNTTKSYSYTTKKLFNKEDIRCLNEDDMLIVMHNKQPILDKKNIYYTQEKYNSKIKETPLKINLPTNNIIKNKSDEEKYINLFKENIKLKVEHKIKEQEENLILEGIKKLDNSSTNRLVEEIWK
>NC_017297|3378914:3462532|3442023_3442407_-|WP_012100893.1|DBSCAN-SWA
MANMELEGMDNLIRKIEDMGKAGTRIENKALKKAGELIVEEAKNNVPVKTEKLKKGLKVSGVRKKGGNKFVLAGIQKGDNSKIFYGKFLEFGTSKMKARPFMGPAYESKKEEAKGIIKDELRRGLGL
>NC_017297|3378914:3462532|3462166_3462532_+|WP_012100934.1|DBSCAN-SWA
MSNLGERLKELRNEAKLSQKDLAKKLGLSSSTVGMIESGKREGNKETIQKIANFFGVSIDYLYGNDVEEITKTESLIDNFLDRLIQEGIIQDPNNIDSTTEDMILNAIKAEIALKLKKKNS
>NC_017297|3378914:3462532|3387920_3388193_-|WP_003361573.1|DBSCAN-SWA
MTKTPLKKVIKSKIKANKELTKEEKLREKMKYEIAIELGLQDKVDQLGWGGLTSEETGRIGGIMTKRKKELKLPKNEEILMMSEIKNSMQ
>NC_017297|3378914:3462532|3383121_3384693_-|WP_012100844.1|DBSCAN-SWA
MGSLSYIVRKSIKNYFKQLKNKPAKAILYVLFIALLVFILIVSPESSGNKRIKDGKEFFNAIVTIVTLYAVFSAINTGTKKGKSFFRLSDVNFLFTAPIPPQRVLLYGFLKELYKSMMMIVFLLFQIPNLYNLFPIKQHGAIPVVVGIFMLMFSYSTIAVLIYSIAAKEDKYRNFIKNILNLLLGLFGAGFLWTLFKVKSIKLAFITFLGLDMFSQIPFIGWNINIFNAAIEGINKLFFINLLGVLLSIIFIIYIVYILKTDYYEDAMSVTEVNERKIERAKKGKGNVDLNKPIKRKNVMGILKSKGAKSIFERQVLEYKRSGFFFVDKMTLVMGVSSLVFGFFMTDKNGSINTVMYFAIYMLLIFTFQGKWAEELSKPYIYLIPESSEIKVFYATLTNHIKNFVDGFVLFLICGIIFKTNPAIILLATLTYVSFGAIFVYVDLVLRRFFGGNISKAVEATLKFILLIIAVLPGIIISVLISFKYKGLFGTVSMYLAMILYNCLISFIGILLSKSIFEKIEMK
>NC_017297|3378914:3462532|3448087_3448552_-|WP_041173254.1|terminase|DBSCAN-SWA
MARPRQPTDLLLVKGKKHLTKAEIEDRKSKEIKAPSDKVKAPSYLPADLKKEFNKIAKELKEIGIITNLDIDALARFIIAKKMYLELTKQILEKPELMIVDKDIVTTQDKLFKQCRSSASDLGLTISSRCKLVIPKKEEPNKKTEEEKLFGSSL
>NC_017297|3378914:3462532|3404475_3405765_-|WP_012100859.1|DBSCAN-SWA
MDYKEAREYIQSKAKFGSNLGLERTEKLLELLGNPHKRLRCIHIAGTNGKGSTTAMISAVLKESGYKVGMYTSPYIEEFEERIQINGHNITKEDLGYIITKVANIVEKVENMGYGNPTEFEIITVAMFYYFCLKEVDFAVIEVGLGGRLDSTNVLEPILSIITSISYDHMNILGETLEEITYEKAGIIKKAPVIMYPQKKEVEKNIEKVCKEKNCDLIKVEDNLINIEIEIIEKNMGQQSFKLKTKEDTYNICLSLLGEHQIKNCITVILALEKLMKLGIKIEKIHIISALKKVKWPARLEIVNKNPLTVIDGAHNIDGIESLKNNVSKYFKYNKLILILGILKDKQVEDMIKTLVPLADRVLTVAPHNDRGESSKELMHIVLKHNESCEHLEDYKECYDKAKFYCEDGDMILICGSLYMVGDMRKLIR
>NC_017297|3378914:3462532|3451415_3451802_-|WP_012100908.1|DBSCAN-SWA
MMNKKNYEKYKKNVENDLRNYPYWLLAIETPGLGSPNRWGEINQNKYNHTSTVEEDMLRDMEKSWKVDVITKVLGQLDPTSKKIIEEWYFRDIMTREEIQESLNLDKNKFYYYRNRTLKKFMAALNYI
>NC_017297|3378914:3462532|3382223_3382931_+|WP_012100843.1|DBSCAN-SWA
MKIALVDNRISNEEKNNLEKKNIKVILCPSSPLLYPAVCGHPDMLLHIMDNKNIILHKNMDKEFVELLKNFGINVILSSNSLKDKYPKDIMLNALNIGDIFMHKLNYTDPTLLSFIKHKKLLDTNQGYSKCSTAIVSENAVITSDIKIGKILRENYIDVLLLPPGDIILPGLDYGFIGGTCGLLDNNTLAFYGNLNMYKYGDKVINFLKKHNVKPIFLSRGKLIDRGSIFCMDIK
>NC_017297|3378914:3462532|3459634_3459856_-|WP_012100926.1|DBSCAN-SWA
MIIKFKDIGYANETFEKNIKEISYKEMVRCVAPYVCSSPSSIWFSFSNEEKTKGHVNANFHTIGYFEIKKEMA
>NC_017297|3378914:3462532|3449997_3450273_-|WP_012100905.1|DBSCAN-SWA
METYCDKGCKKKFEIKEFKERKLKDGVIETYFKCPKCGKKYICFYTDKEIRLLQAKLRSKWSKVSREDIEQLQGKVKVKMDILKGKMLGAQ
>NC_017297|3378914:3462532|3415378_3417175_-|WP_012100866.1|DBSCAN-SWA
MLYCYLKDSWKRKHDLFRNTKDEKVYFISKEDKKILKRVIKLFKPYSKKIICVLACMLISVGISFTIPLISMALMDYGLLNNNLSNVIKYSLEIFFITIAGQAIELLEVKYEAYLSTMVPYELTLKTFKKTMVLKLSDLNKINNTQLMGNISMDVKNICSLLNRESLYVIMQIFNIIGGILGLLMISWKLTIVVISIVPLRYFTIEILSKKRKKNYEKYMINAEEYWSWYGDTLNGVKEIKLLGIGRVKIGEFIKKQRALIINNTKFFYQDKINYCLESITLAFITNILYILGACLTFSGNLSIGGLLAFITYSVKVTSPISTIAGIKYNYINIIPSAKRFFEFMDMESDETLGNLKLERDLQIRNICFKSIYFSYNEDRWNLSNINFNIKSGEKVAIVGMNGAGKSTLFNLLLRLYEPNKGEISINGININDIKLSNYRSLFSIVSQDFYLFNKTIKENIGFKPNIKESNIHNAIARSGAGEFIEKLDEKINTKVGSNGVRLSGGERQKLALARALVSNSKIILFDEGTSNVDIESENKINEVLINELKEEIVLIISHKPKILKYVDKILVLENGVIQDIGNYDELYKKGVLLQYVK
>NC_017297|3378914:3462532|3403182_3404067_-|WP_003357551.1|DBSCAN-SWA
MRYVYVCNTSTDCISKVSIDNFKEENKITLNNELSTRIGPHGICAYNDKLLVANSYSNSLSVVDGKLGREIENYFIGMHCNDVVVYGDKAYVICGDLNNVTVFDMVKKKISKQIPCGDLPHSIVIDKQNEILMISNMGTDNITLIDCKEENRVKNIRVGSYPTKAVFTVDGKYILVCESNLGSDYKGSISIISRKNYKLLYRIPVGNSPVDMCIDEKLCIVSNFGDGTISLIDINYYEKIKDIIVGGMPRGVCKIKDNIYVGDNYKNLFLRINIRTNNKKSIPIGGEPTGILVL
>NC_017297|3378914:3462532|3446393_3448091_-|WP_012100900.1|terminase|DBSCAN-SWA
MSDIARYYTIIYRYACDIVDGKIKACKKHIQACKRFLNDLDKSQNEDYPYFFDYEELYKFYKWAGLFKHRAGVLKGKKIDLVPFQLFIVGNLFCWKHKDTGLRRFRKAYIQIARKNAKSQLLAVIASYECFLSKEQAEVYLAGWDKEQSSIVYREIKYQIESAELLKGKYTDSYGRITHLKSGSFIKPLSREAKNTGDGTNPSLGIVDEYHAHKTSEIYDVILSGMVAREQPLMVIITTAGFDLSRPCFKEYQYVSKILDPNNPTENEEYFVMICELDIEDDIKDESNWIKANPIVATYENGLNYLRGELKAALDAPEKMRNFLTKNMNKWVDMKESGYMNMQKWAECENNKLTFADFEGEECVGGLDLSTKLDLTSIAFEFKRNDKYYPFQHSFMPDETYQKRVREGKYRFDLWKEQGALTKTPGAVIDYAFVKQWIQEQEKKYNLKIKEIGYDPYNATQFVQEMEQEGYVMVEVRQGPYTLNEPTKDFRDQVYDKKLEHSGDGLLTWAIGNAVTKQNAQEFIMLDKAKSSEKIDPAAAVINAHVRGMVVLDDGAGDIFYSPDI
>NC_017297|3378914:3462532|3449291_3449585_-|WP_012100903.1|DBSCAN-SWA
MFKRVKATTRPRPEPPGKQPKKMGNIITIKLNLDTTELDNKLNRLEEQLERIKSLEDTLKLSKDFNEVKNITINNNIDIKDIMKRCVEAAMSMEPLE
>NC_017297|3378914:3462532|3441098_3441680_-|WP_012100891.1|tail|DBSCAN-SWA
MAIKGLHGFRYCVLNEDDEKGFEYEKEIKRLTGARSIKVDNKVNDAKLYGDDQLLETASAIGSIDVDIDVADLTLEQQAELLGYKYENGVLIEDKDFNPPYIAFGFMAPKSSGGKRMVWLLKGKMQPMSDEAKTQDDKVEFQTQKAKFVFMPRVKDGKHKFKADTNITGAPTEEEFFSVDFLKTGKKPVEAGA
>NC_017297|3378914:3462532|3430988_3431384_-|WP_012100883.1|DBSCAN-SWA
MQYLKIINLIDNNGICQYKGLDVNKFFAGSQMVNFEENTCVIKTMEEEIPKNSDLTVLSEDDYISEFKNIENKRLSEKPKSEEEISQEKQQALNAKLLKDNAEIQIELNKQKELNADLLLKIAQLGGNANA
>NC_017297|3378914:3462532|3411343_3411628_-|WP_003405994.1|DBSCAN-SWA
MINNNSVQRKLNDIFNRIFDINLNSINEELFERSLLGDFFCFEPIDLVCLYMEVEKIFNISIPQEYVVENRFNTINDIKEIIIIQLGQEEAIIS
>NC_017297|3378914:3462532|3388492_3389452_-|WP_012100846.1|DBSCAN-SWA
MESKNLIEVRNLKKHFKVGKDAILKAVDGVSFDIRKGETLGLVGESGCGKTTCGRTILGLYEATEGEVRFEGVNIHDFSKKEKREFTKEAQIIFQDPYASLNPRMTVADIIGEGIDIHEIYTGRERLNKIYELLSLVGLNKEHASRFPHEFSGGQRQRIGIARALAIEPKFIVCDEPISALDVSIQAQVVNLLIDLQNKLGLTYLFIAHDLSMVRHISDRVGVMYLGNVVELSNSQELYENPLHPYTKALLSAIPVPDPKVGRDRERIMLHGEVPSPINPKPGCKFAARCKYAKETCKKEKPKLKEIEKDHFVACHLFD
>NC_017297|3378914:3462532|3399434_3400145_+|WP_012100855.1|DBSCAN-SWA
MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIENNKDKIKNCRIEQDRRKSAIPLLDMLKVNARIEPGAIIRDKVLIGENAVIMMGAVINIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAVILEGIKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
>NC_017297|3378914:3462532|3390484_3391402_-|WP_012100848.1|DBSCAN-SWA
MAEISKDKFQIIGIDKNASNEINRPNITYWQDAWRRLKQNKVAIGSLILLILIALMTIIGPYLTPYKYWATDSNIVNMTPNSNHWFGTDMLGRDIFARVWKGGRVSIIIGILGTIIEMTIGVIYGGISGYFGGMVDDIMMRIVEILLSVPYLIVVIIISLILGKGVISLVIAMTITGWCGMARIIRGQILQIREQEYVLAAQALGARPSRIIKKHLLPNTMGILIVNITLDVPSFIFGEAFLSYIGLGIQSPNTSWGSLASAAQPNLMFYPYQLFFPALFISLTMLSFNLLGDGLRDALDPKMRQ
>NC_017297|3378914:3462532|3391417_3392347_-|WP_003405928.1|DBSCAN-SWA
MFKYILKRLGYMLLTLWIVITITFVLMHTIPGDPLASSAKRLPPQIRANYYAKYGLDKPLTTQYAVYMKNLLKGDLGDSLAFAGRSVNTVIKDGLPASARIGIQAVFLGFTLGIILGVVAAFKRNKWPDYIVMFLALIGVSIPSFVFAALLQYIFTVKFMILPTTGWGGAKYTILPTIALSLSPLAIYARYMRNECLDVLGQDYILTAKAKGVSKVSLAWKHIIRNAILPSITILGPQIATILTGSFVIEGIYGIPGLGSSFVGAVNNMDYSMIMGLTVFMATLYIFSLLIVDILYGIIDPRIRITNSK
>NC_017297|3378914:3462532|3457627_3458143_-|WP_012100923.1|DBSCAN-SWA
MTDIKLFERWVKNALKNTFVFIPCRKFFVVVDGYTGFKIPNKFSSYKKIIRKQTFQNLKTGFGIRDGEIDKWDSLDILKDFDMSNKIKATMLPFVYEKSDKMQIFKANDDLIFINKELLKNINIEHYEIYAESPITPLIFRSEDITYITLPIRMNGFKYTIEEKQGELGCI
>NC_017297|3378914:3462532|3454062_3454335_-|WP_012100916.1|DBSCAN-SWA
MKNKIIDFKNTKAVQNRNLKKEYEEPSNMIDNMNWIIKALETDVIDSVDIIFKYNNEILYYGTSNDKTKNEIKQELLYSIKNLYAKAIIE
>NC_017297|3378914:3462532|3430360_3430777_-|WP_012100881.1|holin|DBSCAN-SWA
MNKENIFNGIVAAIGTWFTYVFGAWDTPLAALVGFMLVDYATGMVASYITDKLNSKIGFKGILRKCMILLVLILGVLLDRLLNDGTWVFRTLICYFYIANEGLSIIENVGKCGVNYPPALKNALEQLQEKDMHKEKNQ
>NC_017297|3378914:3462532|3458145_3458688_-|WP_012100924.1|DBSCAN-SWA
MIPEETIKILSIIKAAYPQWARDLKPTDAKTMVNLWSTMLEDYPYNVVQIAIKKIIATNKFPPSVAEVIEAINYITSGGKSEMTEIEAWGLVRKAIKNSAYNAEEEFNKLPSRIQEAIGSHNILHNWSQESINGIETVIGSNFMRSYKQTVIRKKEEKQIPTSIKKMLGNVGQKMIEGDK
>NC_017297|3378914:3462532|3395610_3396489_+|WP_012100852.1|DBSCAN-SWA
MSIFKGSGVAIITPFTETGVDFDKLSELIEWHIKSKTDAIIVCGTTGEATTMTETEKKETIKFVVDKVNKRIPVIAGTGSNNTAASIAMSKWAESIGVDGLLVITPYYNKTTQKGLVKHFRAVSDAVNTPIIIYNVPGRTGLNIAPSTLKELCKDKNIVAVKEASGNISQIAQIKALCGDKLDIYSGNDDQIIPILALGGIGVISVLANVIPEDVHNICELYLTGKVNEALKIQLDSLALTNALFIETNPIPVKTAMNLMNMKVGDLRLPLCEMNENNLEILKKELKACNLM
>NC_017297|3378914:3462532|3450973_3451207_-|WP_012100907.1|DBSCAN-SWA
MKGCEDMLSMYTGFLCYSCRNEFILLSEELERTKGYLVCPYCTSRKVKKQNSTDNLKECMKEKVYKRVRGAIRQVTR
>NC_017297|3378914:3462532|3434139_3435009_-|WP_012100886.1|tail|DBSCAN-SWA
MQKLIYRNSKGQEVTLSNSRPFVLEKIENVANTATSINTSISAGQDGVSIDNISIKEKLLPITGGIVGNNFEDIDRKREYLTSVFNPKFHGELIYTNNATSRKIKGRVQDITFQDKVGSIQKFLVQILVPNPFWEDIYTKKEEVALWVGDFEFPLEIPQDTGIEMGHRVSNLIVNINNTGAVECGMRIQFKALATVINPSLFNINTREFIKINKTLNAGDVLECTTEFSNKRIEMIRNNGSRENVFNWIDLDSEFLQLEPGDNLLRYNADSGIDNLEVAIYYTPLYLGV
>NC_017297|3378914:3462532|3386166_3387057_-|WP_003405920.1|DBSCAN-SWA
MKDKLVKAIAKDGQVRIIGAITTELVNEGVKLHNCAPTAAAALGRMLTAGALMGTTLKSEKDTLTLQIHGGGIAKGVVVTSYADGHVKGYIGNPTADIEPNSKGKLDVSGIIGKNGNLLVIRDMGLKEPYIGQVPIYTGEIGEDLAYYYTVSEQTPSAVGLGVLVDKDLSIKSAGGFIIQMMPGADEMLADLISYRLEEIPSITEMISKGMTIEEILEYIFEDMDLKILESIAPEYRCDCSREKVERALASIGQKDLKEIYDEGKEEELKCHFCNKAYVFSHDEVGDILENYYSEK
>NC_017297|3378914:3462532|3417795_3418452_-|WP_003406003.1|DBSCAN-SWA
MLSINKLYRTYGSGETKVDAIKNINLTINQGEFVAIVGASGSGKSTLLHAMAGLDKPTGGNIIIDNQDIYDLDVDSLAAFRRKKIGFVFQFFNLIPVLTLEENIQLPILLDHEKIDKDYLNELLDILDLRGRRDHLPSQLSGGQQQRAAIARALINKPSIIFADEPTGNLDKKNSKEVMELLKLSCKKYKQTLVIVTHDLEIASKADRIITISDGEVK
>NC_017297|3378914:3462532|3394595_3395588_+|WP_003357473.1|DBSCAN-SWA
MNYNVAVVGATGMVGRKFIEILESRNFPIENIYFFASKRSAGKTLKFKTSEILVEELKEDNIKNKKIDFALFSAGGDISKDFAPVFVKYGATVIDNSSAWRMDPEVPLVVPEVNAEDIKWNKGIIANPNCSTIQALVALKPLHDKYKIKRIVYSTYQAVSGAGLSGFNDLKNGYTGESPKKFSYAIAGNILPHIDVFLENGYTKEEMKMIDETKKMLHDDTLKITATTARVPVFHGHSESINVELEKPFELEDIFEIYKNAEGIVLKDDVANLVYPMPIDVAGHDEVYVGRIRRDFSLDNGLNLWVVADNIRKGAALNAIQIAEHIIKSK
>NC_017297|3378914:3462532|3422543_3422825_+|WP_012100871.1|DBSCAN-SWA
MFGDRLKELREEKELTQEELGKLLSVSRQTVSGYEAEVIEPNINNLVRLSDIFNVSLDYLLGRTKERYNLNLENKKNKELLLDLIKVIDKYKK
>NC_017297|3378914:3462532|3460367_3460610_-|WP_041173183.1|DBSCAN-SWA
MKTTDLNLNVSTGTLLYIDIDIFRFLYDQEIFCITVQFLDEEDYKFLEEINLEKNKSILNHNDLKRIALNWIFENVEIVK
>NC_017297|3378914:3462532|3454368_3454590_-|WP_012100917.1|DBSCAN-SWA
MKRQCSNCRFWIPTIDNGFCEKEISKRCEFDDTCNKYKPKLLLDKMGIDSVEFAGISLTIVVIVLILYGAGLI
>NC_017297|3378914:3462532|3423522_3424431_-|WP_012100874.1|DBSCAN-SWA
MEITGQLYAIFRVGEKKYKTVGAIAGYQRHMEREQQTPNANPNISNVRLLGSNFIMADVKEYIEGIKLRKNGVIARDLLLTASPKFFKDLSIEEKQKWVNTNIKFLERHFGENCVYATLHRDETTWHISALVVPRFWEEKKKRYVLANSRYFDGKKKLSKWQDKYSSFIKQQFKELNRGQRGSKAHHVKISNFYRILNSGLDSYNALEVIKKSKQSIALKEQLENVQSTLNKYKDYAKLTTLEKQELSNSLKDIKQDKEVFKETIKAMSEIYKISQQSIAQIINSVDKNLQRGEPDDKERRV
>NC_017297|3378914:3462532|3412408_3413524_-|WP_012100864.1|DBSCAN-SWA
MNNKEKALIYPYDREFSTIIRHQSICDYEIVEVVAPNGWGLSEKDASYADGGQDLNIIVNNNFESTLNNCDTLILSNSALKLDFKESIYPKVVQAAEKNKKIISTAKFDIKEIEMIEEVCKYKGNIFIQYPLNKNYEICSYVDKLEIQEIKTPVIFVMGVGENAHKFEIQLSVRENLFNMGYKVSQVGSRNYCEMFNFHSFPEFMYSNMYSETEKIKLFNNFIKNIETQENPDVIIIGIPGTIMRINNKATYDFGVLAFEVSQAVKPDASILSVLYENYLPSFFEKIAQEVKYKFACDISCFNYVNSMIDWNYFEINTEAKYIDVTLDLVNNKIKELNNSIPIFNIMNENEGSKITEHLVNKLACEEYEVL
>NC_017297|3378914:3462532|3427367_3427613_-|WP_012100877.1|DBSCAN-SWA
MKKVVISLLTGLLIGASTRFVGVANAVAPAEDNGRENGYYMYCLDKNKPVWVSLDKVKEGEKFLYLSNLKNNTVIKLVKIN
>NC_017297|3378914:3462532|3448818_3449292_-|WP_012100902.1|DBSCAN-SWA
MAQRSLRPCKQRGCKNLTRDITGYCLEHIHIYEERKAQRNKHYDKRIRYNKDKKYTKFYHSKEWERLREDILKTYNGIDIYSYYIENKIVIANTVHHIEEIKDNWDKRLDVDNLFPLSDVTHNNIHSLYSKDKKETQRLLVELLERFIKQFGISPLP
>NC_017297|3378914:3462532|3433068_3434088_-|WP_079992194.1|DBSCAN-SWA
MDNYESFSITRRFFECGEFEFKINSNKLHTDKLVKNNLLLLGKDYNKVGVILHREFVYGEEGQETETLLIKGVMLQGLTKRRIIIPNTGQEFDSCIGYQETIMKYFINRNCVNPIDSNRKIDNLIIAVDKKRGEDDRWRGAYENLDEKLKEIGEYSKLGWNIMLDHKQKKFIFDVLQGKDLTVNQDSNPPVIFRNDFNNIKTRHYTESIINSRNSIYIGNKEKLVLNLGDITGFERMETFLDSTSEEVEDIKKEGLVKLEEIKELKTFELEINPNNTFVYEKDYDLGDIVTIQDKKLKVTMDSRIIEAQEVYSNDGMKLKATFGTRIPSLLAVLKRMVK
>NC_017297|3378914:3462532|3423395_3423545_-|WP_012100873.1|DBSCAN-SWA
MTKKEEYELKLKIIGQWIEIKPNEELMESLKNAQRELKELELVEYQREL
>NC_017297|3378914:3462532|3461723_3461957_-|WP_012100933.1|DBSCAN-SWA
MTFRQLRERAGLTVKESAKRLGIKPGTLNKYEIAIRNPSQIVMLKMVQAYNCTHEDVMIAYKINLERAVQKFGRANP
>NC_017297|3378914:3462532|3389451_3390471_-|WP_012100847.1|DBSCAN-SWA
MERILEVRNLRVSYHTYAGEVQSVRNISFHLNKGETLAIVGESGCGKTVTAKAIMRLIQEPPGEIKEGSEIIFNDKNILDMKEQELRQLRGADISMIFQDPMTSLNPTMKVGKQIAESLIIHRGMNKSEAFKEAINILQLVNIPNAEKRANQYPHEFSGGMRQRAMIAIALACDPKVLIADEPTTALDVTIQAQIMNLIGDLQKKLNTAVIMITHDLGVVADTAHRIQVMYAGQIIERGITNEIFYESKHPYTWALLQSVPRLDTKHKGELYSLEGTPPDLIKPPKGCPFASRCEYCMKICKEQMPKVTKLTETHEVSCWLQHPMSPKVHSSFLPGGEK
>NC_017297|3378914:3462532|3427625_3427808_-|WP_012100878.1|DBSCAN-SWA
MGKSKQTIANQNWENKNREYASYLKSRSSARSFIRNKATLEDIEELRNLLKEREELLKRE
>NC_017297|3378914:3462532|3456065_3456524_-|WP_012100920.1|DBSCAN-SWA
MEKLILDACCGSKMFWFDKENENTIYMDNRELEDELCDGRKLIVNPDIIGDFRNIPFEDNTFKLVVFDPPHLIKAGENSWLAKKYGKLNNDWPIDIKQGFNECMRVLDKYGVLIFKWNEEQIKIKDILKVIDYKPLFGNKRAKTHWLVFMKK
>NC_017297|3378914:3462532|3443052_3443208_-|WP_012100896.1|DBSCAN-SWA
MGEENTEPIIYGKEELETMTVEQLKSIAKDKNIVGYSSMNKADLITAILTP

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012100841.1|3378914_3380822_-|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.1e-138	39.0
WP_012100842.1|3381169_3382069_-	putative sporulation protein YtxC	NA	NA	NA	NA
WP_012100843.1|3382223_3382931_+	hypothetical protein	NA	NA	NA	NA
WP_012100844.1|3383121_3384693_-	ABC transporter permease	NA	NA	NA	NA
WP_003405920.1|3386166_3387057_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_003405923.1|3387094_3387835_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_003361573.1|3387920_3388193_-	small, acid-soluble spore protein, alpha/beta type	NA	NA	NA	NA
WP_012100846.1|3388492_3389452_-	ATP-binding cassette domain-containing protein	Q6GZ03	Mycoplasma_phage	2.2e-10	35.2
WP_012100847.1|3389451_3390471_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.2e-16	29.7
WP_012100848.1|3390484_3391402_-	ABC transporter permease	NA	NA	NA	NA
WP_003405928.1|3391417_3392347_-	ABC transporter permease	NA	NA	NA	NA
WP_003357473.1|3394595_3395588_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_012100852.1|3395610_3396489_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_012100853.1|3396711_3397467_+	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_012100855.1|3399434_3400145_+	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
WP_003357563.1|3400260_3400962_-	single-stranded DNA-binding protein	A0A2H4J8K3	uncultured_Caudovirales_phage	6.0e-50	50.2
WP_012100856.1|3401039_3401537_-	hypothetical protein	NA	NA	NA	NA
WP_012100858.1|3402652_3403180_+	DUF4364 family protein	NA	NA	NA	NA
WP_003357551.1|3403182_3404067_-	YncE family protein	NA	NA	NA	NA
WP_003357396.1|3404206_3404467_+	TIGR03905 family TSCPD domain-containing protein	NA	NA	NA	NA
WP_012100859.1|3404475_3405765_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_012100860.1|3406340_3408986_-|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	4.8e-177	43.3
WP_012100861.1|3409006_3409513_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012100862.1|3410099_3411344_-	S8 family serine peptidase	NA	NA	NA	NA
WP_003405994.1|3411343_3411628_-	peptide maturation system acyl carrier-related protein	NA	NA	NA	NA
WP_012100864.1|3412408_3413524_-	TIGR04066 family peptide maturation system protein	NA	NA	NA	NA
WP_012100865.1|3413564_3414971_-	Cys-rich peptide radical SAM maturase CcpM	NA	NA	NA	NA
WP_003405999.1|3415060_3415258_-|bacteriocin	CLI_3235 family bacteriocin precursor	NA	NA	NA	NA
WP_012100866.1|3415378_3417175_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.4e-40	28.3
3416520:3416539	attL	NA	NA	NA	NA
WP_003406003.1|3417795_3418452_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	4.6e-12	27.1
WP_012100868.1|3421500_3421746_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012100870.1|3422235_3422472_+	helix-turn-helix transcriptional regulator	A0A0A7RUG5	Clostridium_phage	3.9e-22	67.9
WP_012100871.1|3422543_3422825_+	helix-turn-helix transcriptional regulator	A0A0A7S0F1	Clostridium_phage	6.1e-38	88.0
WP_012100872.1|3422845_3423319_-	hypothetical protein	NA	NA	NA	NA
WP_012100873.1|3423395_3423545_-	hypothetical protein	NA	NA	NA	NA
WP_012100874.1|3423522_3424431_-	recombinase	NA	NA	NA	NA
WP_012100875.1|3424421_3426047_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_012100876.1|3426920_3427322_-	recombinase family protein	A0A2H4J078	uncultured_Caudovirales_phage	7.4e-29	57.0
WP_012100877.1|3427367_3427613_-	hypothetical protein	NA	NA	NA	NA
WP_012100878.1|3427625_3427808_-	hypothetical protein	A0A0A7RTH9	Clostridium_phage	7.7e-18	86.0
WP_012100879.1|3428428_3429166_-	hypothetical protein	NA	NA	NA	NA
WP_012100880.1|3429318_3430221_-	SH3 domain-containing protein	A0A0A7RVQ3	Clostridium_phage	3.4e-42	54.7
WP_012100881.1|3430360_3430777_-|holin	phage holin family protein	M9Q253	Clostridium_phage	1.2e-34	56.6
WP_012100882.1|3430873_3430996_-	XkdX family protein	A0A0A7S0E7	Clostridium_phage	6.9e-07	62.5
WP_012100883.1|3430988_3431384_-	hypothetical protein	NA	NA	NA	NA
WP_012100884.1|3431397_3433062_-	hypothetical protein	E2ELJ8	Clostridium_phage	4.7e-77	53.0
WP_079992194.1|3433068_3434088_-	hypothetical protein	E2ELJ7	Clostridium_phage	2.4e-116	59.4
WP_012100886.1|3434139_3435009_-|tail	phage tail family protein	E2ELJ6	Clostridium_phage	2.9e-110	69.7
WP_012100890.1|3440775_3441063_-	hypothetical protein	E2ELJ2	Clostridium_phage	1.5e-15	48.4
WP_012100891.1|3441098_3441680_-|tail	tail protein	E2ELJ1	Clostridium_phage	6.9e-60	59.6
WP_154018643.1|3441786_3442029_+	hypothetical protein	NA	NA	NA	NA
WP_012100893.1|3442023_3442407_-	HK97 gp10 family phage protein	E2ELI9	Clostridium_phage	1.4e-29	51.4
WP_012100894.1|3442399_3442726_-|head	phage head closure protein	E2ELI7	Clostridium_phage	3.5e-05	33.3
WP_012100895.1|3442706_3443036_-|head,tail	phage gp6-like head-tail connector protein	Q9ZXF3	Bacillus_phage	6.1e-05	33.0
WP_012100896.1|3443052_3443208_-	termination factor Rho	NA	NA	NA	NA
WP_012100897.1|3443227_3444355_-|capsid	phage major capsid protein	A0A1B1P7R4	Bacillus_phage	3.6e-121	62.1
WP_012100898.1|3444347_3445148_-|protease	Clp protease ClpP	A0A0A7RTN2	Clostridium_phage	1.7e-88	67.6
WP_012100900.1|3446393_3448091_-|terminase	terminase large subunit	A6M948	Geobacillus_virus	6.4e-199	60.9
WP_041173254.1|3448087_3448552_-|terminase	phage terminase small subunit P27 family	Q9ZXG2	Bacillus_phage	6.7e-50	61.9
WP_012100902.1|3448818_3449292_-	hypothetical protein	A0A0A7RUV1	Clostridium_phage	4.6e-14	37.8
WP_012100903.1|3449291_3449585_-	hypothetical protein	NA	NA	NA	NA
WP_012100904.1|3449618_3449960_-	hypothetical protein	NA	NA	NA	NA
WP_012100905.1|3449997_3450273_-	hypothetical protein	NA	NA	NA	NA
WP_012100906.1|3450426_3450972_-|integrase	site-specific integrase	E2ELN7	Clostridium_phage	2.5e-56	60.7
WP_012100907.1|3450973_3451207_-	hypothetical protein	NA	NA	NA	NA
WP_012100908.1|3451415_3451802_-	nitroreductase	A0A0A7RTL7	Clostridium_phage	2.0e-47	70.9
3451774:3451793	attR	NA	NA	NA	NA
WP_012100912.1|3452368_3453418_-	nucleoid-associated protein	J9QE81	Clostridium_phage	3.9e-37	29.7
WP_012100915.1|3453839_3454025_-	hypothetical protein	NA	NA	NA	NA
WP_012100916.1|3454062_3454335_-	hypothetical protein	NA	NA	NA	NA
WP_012100917.1|3454368_3454590_-	hypothetical protein	NA	NA	NA	NA
WP_012100918.1|3454625_3454988_-	hypothetical protein	NA	NA	NA	NA
WP_012100919.1|3455020_3456037_-	DNA (cytosine-5-)-methyltransferase	A0A0A8WIK9	Clostridium_phage	1.0e-103	52.9
WP_012100920.1|3456065_3456524_-	methyltransferase	A0A0E3Y6D6	Fusobacterium_phage	5.1e-66	73.3
WP_012100921.1|3456569_3457313_-	hypothetical protein	NA	NA	NA	NA
WP_012100922.1|3457349_3457637_-	hypothetical protein	NA	NA	NA	NA
WP_012100923.1|3457627_3458143_-	hypothetical protein	NA	NA	NA	NA
WP_012100924.1|3458145_3458688_-	hypothetical protein	A0A2K9V2Y3	Faecalibacterium_phage	1.1e-08	28.6
WP_012100925.1|3458688_3459525_-	hypothetical protein	A0A1S5SFJ6	Streptococcus_phage	8.1e-46	63.5
WP_012100926.1|3459634_3459856_-	hypothetical protein	NA	NA	NA	NA
WP_012100927.1|3459871_3460054_-	hypothetical protein	NA	NA	NA	NA
WP_012100928.1|3460117_3460324_+	KTSC domain-containing protein	A0A0K1LMB5	Caulobacter_phage	1.3e-10	52.2
WP_041173183.1|3460367_3460610_-	hypothetical protein	NA	NA	NA	NA
WP_012100930.1|3460632_3461391_-	hypothetical protein	A0A288WG93	Bacillus_phage	1.1e-52	45.9
WP_012100933.1|3461723_3461957_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012100934.1|3462166_3462532_+	helix-turn-helix transcriptional regulator	A0A1L2BY72	Clostridium_phage	1.3e-08	48.6