CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Prophage number
NC_014155	Thiomonas intermedia K12 plasmid pTINT02, complete sequence	0 crisprs	NA	0	0
NC_014153	Thiomonas intermedia K12, complete genome	9 crisprs	Cas14u_CAS-V,c2c9_V-U4,csa3,DEDDh,DinG	2	3
NC_014154	Thiomonas intermedia K12 plasmid pTINT01, complete sequence	0 crisprs	DEDDh	0	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_014153_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_1

157050-157134

Orphan

Consensus_repeat	Method
CACCTCCTCCACTTGTGGGGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_1

>merge|NC_014153|1|157050-157134|CRISPRCasFinder
CACCTCCTCCACTTGTGGGGAGGGCCGGGAGGGGCATCCGAAGCGCCGCGTAGCGCTGTTCTCACCTCCTCCACTTGTGGGGGAG

>NC_014153|1|1|157050-157134|CRISPRCasFinder
CACCTCCTCCACTTGTGGGGAGG	GCCGGGAGGGGCATCCGAAGCGCCGCGTAGCGCTGTTCT
CACCTCCTCCACTTGTGGGGGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013121943.1\|153169_154375_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NC_014153.1\|WP_013121952.1\|163797_164154_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|339877
NC_014153.1\|WP_013121940.1\|149262_151290_+\|transketolase	unknown	unknown	gnl\|CDD\|183723
NC_014153.1\|WP_013121947.1\|157213_157885_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013121954.1\|165778_166078_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013104298.1\|145751_146711_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176111
NC_014153.1\|WP_013121945.1\|155602_156160_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239267
NC_014153.1\|WP_013121946.1\|156156_156921_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319830
NC_014153.1\|WP_081440370.1\|151312_152020_+\|phosphoglycolate-phosphatase	unknown	unknown	gnl\|CDD\|237310
NC_014153.1\|WP_013121953.1\|164196_165687_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238624
NC_014153.1\|WP_013121956.1\|166662_168111_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl\|CDD\|235489
NC_014153.1\|WP_013121944.1\|154428_155493_+\|fructose-bisphosphate-aldolase-class-II	unknown	unknown	gnl\|CDD\|181691
NC_014153.1\|WP_013104299.1\|147119_148199_+\|class-1-fructose-bisphosphatase	unknown	unknown	gnl\|CDD\|236458
NC_014153.1\|WP_013121950.1\|159582_162213_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NC_014153.1\|WP_013121942.1\|152091_153099_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NC_014153.1\|WP_013121955.1\|166177_166570_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NC_014153.1\|WP_013121949.1\|159093_159582_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225527
NC_014153.1\|WP_013104300.1\|148355_149231_+\|phosphoribulokinase	unknown	unknown	gnl\|CDD\|237970
NC_014153.1\|WP_081440417.1\|162364_163696_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NC_014153.1\|WP_013121948.1\|158002_159094_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013121943.1\|153169_154375_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NC_014153.1\|WP_013121952.1\|163797_164154_+\|hypothetical-protein	gnl\|CDD\|339877	pfam16998, 17kDa_Anti_2, 17 kDa outer membrane surface antigen. 17kDa_Anti_2 is a surface protein that is found in several Proteobacteria species.	5.39078e-06
NC_014153.1\|WP_013121940.1\|149262_151290_+\|transketolase	gnl\|CDD\|183723	PRK12753, PRK12753, transketolase; Reviewed.	0
NC_014153.1\|WP_013104298.1\|145751_146711_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176111	cd08419, PBP2_CbbR_RubisCO_like, The C-terminal substrate binding of LysR-type transcriptional regulator (CbbR) of RubisCO operon, which is involved in the carbon dioxide fixation, contains the type 2 periplasmic binding fold. CbbR, a LysR-type transcriptional regulator, is required to activate expression of RubisCO, one of two unique enzymes in the Calvin-Benson-Bassham (CBB) cycle pathway. All plants, cyanobacteria, and many autotrophic bacteria use the CBB cycle to fix carbon dioxide. Thus, this cycle plays an essential role in assimilating CO2 into organic carbon on earth. The key CBB cycle enzyme is ribulose 1,5-bisphosphate carboxylase/oxygenase (RubisCO), which catalyzes the actual CO2 fixation reaction. The CO2 concentration affects the expression of RubisCO genes. It has also shown that NADPH enhances the DNA-binding ability of the CbbR. RubisCO is composed of eight large (CbbL) and eight small subunits (CbbS). The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.10503e-89
NC_014153.1\|WP_013121945.1\|155602_156160_+\|thioredoxin-family-protein	gnl\|CDD\|239267	cd02969, PRX_like1, Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic cysteine found in PRXs, which aligns to the second cysteine in the CXXC motif of TRX. In addition, these proteins do not contain the other two conserved residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF.	7.93514e-91
NC_014153.1\|WP_013121946.1\|156156_156921_+\|HAD-family-hydrolase	gnl\|CDD\|319830	cd07528, HAD_CbbY-like, subfamily of beta-phosphoglucomutase-like family, similar to Rhodobacter sphaeroides xylulose-1,5-bisphosphate phosphatase CbbY. This family includes Rhodobacter sphaeroides and Arabidopsis thaliana xylulose-1,5-bisphosphate phosphatase CbbY which convert xylulose-1,5-bisphosphate (a potent inhibitor of Ribulose-1,5-bisphosphate carboxylase/oxygenase, Rubisco), to the non-inhibitory compound xylulose-5-phosphate. It belongs to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), Saccharomyces cerevisiae phosphatases GPP1 and GPP2 that dephosphorylate DL-glycerol-3-phosphate and DOG1 and DOG2 that dephosphorylate 2-deoxyglucose-6-phosphate, and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.66266e-90
NC_014153.1\|WP_081440370.1\|151312_152020_+\|phosphoglycolate-phosphatase	gnl\|CDD\|237310	PRK13222, PRK13222, N-acetylmuramic acid 6-phosphate phosphatase MupP.	7.54917e-76
NC_014153.1\|WP_013121953.1\|164196_165687_+\|amidohydrolase-family-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	3.38498e-99
NC_014153.1\|WP_013121956.1\|166662_168111_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NC_014153.1\|WP_013121944.1\|154428_155493_+\|fructose-bisphosphate-aldolase-class-II	gnl\|CDD\|181691	PRK09196, PRK09196, fructose-bisphosphate aldolase class II.	0
NC_014153.1\|WP_013121948.1\|158002_159094_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	3.34543e-121
NC_014153.1\|WP_013121950.1\|159582_162213_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NC_014153.1\|WP_013121942.1\|152091_153099_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NC_014153.1\|WP_013121955.1\|166177_166570_+\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.70001e-48
NC_014153.1\|WP_013121949.1\|159093_159582_-\|hypothetical-protein	gnl\|CDD\|225527	COG2980, RlpB, Rare lipoprotein B [Cell envelope biogenesis, outer membrane].	3.44277e-18
NC_014153.1\|WP_013104300.1\|148355_149231_+\|phosphoribulokinase	gnl\|CDD\|237970	PRK15453, PRK15453, phosphoribulokinase; Provisional.	0
NC_014153.1\|WP_081440417.1\|162364_163696_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	2.35205e-136
NC_014153.1\|WP_013104299.1\|147119_148199_+\|class-1-fructose-bisphosphatase	gnl\|CDD\|236458	PRK09293, PRK09293, class 1 fructose-bisphosphatase.	0

>NC_014153.1|WP_013121946.1|156156_156921_+|HAD-family-hydrolase
MNSTPLRALIFDVDGTLAETERDGHRIAFNQAFADAGLDWHWDVPTYGRLLAITGGKERMLAYWQEIDPQAAAAPEAAGLIAELHRRKTAHYVRLVAEGGIALRPGVRRLLEQARDAGLRLAIATTTTPDNVEALIHATLGAGGMDWFEVVGAGDAVPRKKPDPGIYTWVLERMGLAPEQCLAFEDSTNGLRAAHGAGLRTVVTTGAYTHHENFDGALAWLDGLGEAGAPATGRIGSQPWSGVVGLSELRQWAD
>NC_014153.1|WP_013121945.1|155602_156160_+|thioredoxin-family-protein
MAATADPLQRGFPAPDFHLPGIDGSNYTLAELRGPKGLLVMFICNHCPYVQAVADRMVRDARELRALGVHAVAINSNDVSAYPEDSFDNMKLFAAQHGFGFPYLYDETQAVAKAYGAVCTPDFFGFNADLKLQYRGQLDASRKQAAPTDARRDLFEAMKQIAETGIGPAEQYPSIGCSIKWKGEA
>NC_014153.1|WP_013121944.1|154428_155493_+|fructose-bisphosphate-aldolase-class-II
MALISLRQLLDHAAEHSYGVPAFNVNNLEQVRAIMEAADETNSPVILQASAGARKYAGAPFLRHLIEAAVEEWPHIPVVMHQDHGTSPGVCQRSIQLGFSSVMMDGSLGTDGKTPTTYEYNVDVTRRVVEMSHSCGVSVEGELGCLGSLETGTAGEEDGIGAEGTLDHSQLLTDPEEAADFVKKTQVDALAIAIGTSHGAYKFTRQPTGDILAIGRIKEIHARIPNTHLVMHGSSSVPQEWLKIINSYGGDMGETYGVPVEEIVEGIKHGVRKVNIDTDLRMASTGATRKFLAEHPKEFDPRKFLIASTKAMKEICKARYEAFGTAGNASKIKPITLDAMVALYEKGALDPKIN
>NC_014153.1|WP_013121943.1|153169_154375_+|phosphoglycerate-kinase
MQILTFEEVCKRGFAQDKRVFIRADLNVPFNDKGEITEDTRVRASVPAVKMALDAGAGVMITSHLGRPTEGEFKPEDSLAPVAKRLSELLGLPVKLQANWVDGGFDVRPGEVVMLENARVNKGEKKNDDALSQKIAKLCDIYVNDAFGTAHRAEATTYGIAKYAPIACAGPLLAAEIDAISRALEKPARPLVAIVAGSKVSTKLTILQALADKVDGLIVGGGIANTFMLAEGLPIGKSLAESDLVDEAKKVIAKMKERGAEVPIPEDVVVAKQFSATAEATVKDAKDVAADDLILDIGPKTAAKLAAKLKTAGTIVWNGPVGVFEFDAFANGTKVLAEAIASSPAFSIAGGGDTLAAIAKYGITDRIGYISTGGGAFLEVLEGKQLPAFEILQQRAKQPLS
>NC_014153.1|WP_013121942.1|152091_153099_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTIRIAINGFGRIGRMVFRAVAQEAEFKDLEIVAINDLLEPDYLAYMLQYDSVHGRFNGTVGVEGNNLVVNGKKIRLTAERDPANLKWNEVNADVVVEATGFFLTLDTCQKHIDAGAKKVVQSAPSKDDTPMFVYGVNHAKYAGEKIVSAASCTTNCLAPVAKVLNDNFGIKRGLMSTVHAATATQKTVDGPSSKDWRGGRGILDNIIPSSTGAAKAVGKVIPELNKKLTGMAFRVPTPDVSVVDLTVELNKEASYADICAAMKAASEGPLKGVLGYTEDKVVSTDYRGCSMPSIFDAEAGIALDSTFVKVVSWYDNEYGYTCNMMRFVKHVASN
>NC_014153.1|WP_081440370.1|151312_152020_+|phosphoglycolate-phosphatase
MTQAMFDLVMFDLDGTLVETAPEIADAVNDLLRDQQLPEVSEHLIRAWIGHGTRELMLHAYAHATGLEEETVRRTGTLDILMPRFAEFYAVRTGQRSRLYPDVLSTLKALRAAQVRIALVTNKEQRFATTVLMVHGIRHYFDMVVAGDTLEAKKPDPLPVRYCLDALKVPADRALFVGDSEIDVATARAAGVAVWAVPYGYNHGKSIALAEPDRIIPTVAAVAEAVRASALHASD
>NC_014153.1|WP_013121940.1|149262_151290_+|transketolase
MTTVQIDTQQRRRLANAIRFLAIDGVQAANSGHPGAPMGMADIAEVLWRNHLHHNPANPHWANRDRFVLSNGHGSMLIYALLHLTGYDLPIEELKRFRQLHSKTPGHPEVGYTPGVETTTGPLGQGIANGVGMALAEKVLAAQFNQPGHAIVDHHTYVFLGDGCLMEGISHEVCSLAGTLKLNKLIAYYDDNGISIDGHVEHWFSDNTAQRFQAYGWNVIGPIDGHDAVAVEKATAEAKTSDKPTLVICRTTIGWGSPNKAGTHDVHGAALGQAEADATRKALGWDYGPFEIPADIYQAWDAKFHGAKLEADWNERFAAYEKAHPALAAEFKRRMVGDLPADWGQTVQTLYAKAREVTAATATRKSSQIALETLVPALPGLFGGSADLTGSNLTAVKASHSFEKAAPGTAFNYLSYGVREFGMVAMMNGMALHGGFLPYGGTFLMFSDYSRNGVRMSALMKQRVIHVFSHDSIGLGEDGPTHQPIEQPSSLRLIPNLDVWRPADVLETAVAWKHAIERKHGPSALLLSRQNLVSTPHPEDAERTISRGGYVLSEAQGGKPQIVLIATGSEVEIALKAQGMLAEQGVAARVVSMPCTNAFDRQDAAYRNEVLPAGLPRVAIEAGHPDFWHKYVGLNGGIVGIATFGESAPAPQLYQHFKVTAEHAVAVAKSVLQAA
>NC_014153.1|WP_013104300.1|148355_149231_+|phosphoribulokinase
MSVKHPIIAITGSSGAGTTTVMRSFQHIFRREQLTAQIVEGDSFHKFNRMEMREEMKKQEAAGNRHFSHFGPDANLLGELETVFKTYGETGGGKVRKYIHDAGEAAEFGVEPGNFTEWKDIKPGSDLMFYEGLHGGYASGEINVAKQVDLLVGVVPIINLEWIQKLHRDQIQRGYSQEAVMDTILRRMPDYVHHIAPQFSRTHVNFQRVPTVDTSNPFIAKDIPTLDESMVVIRFANPKGIDFPYLLSMLHDSWMSRPNTLVVPGGKMGIAMQLIFTPMILRLMDLKRRAG
>NC_014153.1|WP_013104299.1|147119_148199_+|class-1-fructose-bisphosphatase
MQSGRTTVSKFLIEQLHGTDDQADLAALLVDVTAAVKAISAMTSKGALGGFLGALDTQNVQGEVQKKLDVLSNDAMIQACEWGGLVAGMASEEMDDPYTLPKEFERGPYMLIFDPLDGSSNTDVNVSVGTIFSVLRHTKIGDPTVADYLRPGVEQVAAGYAIYGPATMLVLTVGKGTHGFTLDREIGNFILTHPNLQIPADTSEFAINTSNERFWEPPIQRYVAECKAGKTGPRGRDFNTRWIASMVADVHRILMRGGIFMYPKDTKDPSKPGRLRLMYEANPIGMIIEQAGGAASTGRGRILEVQPSSLHQRVPVMLGSKNEIERLERYHAEYDRGEDKAFESPLFKERSLYRDEASR
>NC_014153.1|WP_013104298.1|145751_146711_-|LysR-family-transcriptional-regulator
MKNATIRQLRVFSAAARHLHFGKAAQEMHLTPPAVSMQIRELESQVGLPLFERQGKSVSLTLTGEYLVVYARKVLATLKDAEDAMARLRGIKAGRLTIGMVSTAQYFVPRLLARFHAEYPHVEVRLSVGNREQLVSHLQNSELDLAIMGRPPRDVATRAEPFAAHPMGIIAPPQHPLSTGGPHSATLLTQFNFIIREPGSGTRATFEEYLHQHQMELPLFTEMQSNETIKQAVMANMGISFLSLHTIDLELRNNLLTVPSIEGMPLLRRWYAVNSLAKLLSPGAEAFRYFILEHGESFLAETFGTDILAPGKDLANAEP
>NC_014153.1|WP_013121947.1|157213_157885_-|hypothetical-protein
MPFFPPRSPISGRLSHTLAALGLSAAALLPTAFAQAAPAPVPDNAPSFTAGPDDVMRVLPAQLLPALQVNCHGVKIAAPAWRAQLDASAALLVNLNQVTVPEKQAVLPMALLCPAPSPLAAAWSRAAEQASNLVKLDFPGAPEQVTGASFIGPKGGRVLIVNRSAQAVRVNLGTWVSKTARLDQYTEPGAAAQPPKVEHLRRALGTQDAQGILLPPMSLSVVG
>NC_014153.1|WP_013121948.1|158002_159094_-|DNA-polymerase-III-subunit-delta
MQLAADQLDAHLASKLGALYVVYGDETLLVNEAVDAIRARARQQGFDERESHTVERGFDWSHLLAGSREISLFGGRRLIELRIPGGKPGRDGGEALAALSGHLSPDVMAVVILPRLDAATQKSAWFSALSQGGVAVRVDSVELAQLPRWIAARLQRHGFTLPAGDAGRALTDFLVARVEGNLLAAHQEIEKLALLCPPGPLDPDTVEQAVLNVARYSVFKLGEAVLGGDVARLRRMLDGLQAEGVAPVLVHWTLADDIRAWLRIRQGLDAGQALPALLRANRIWGVKEKLLERALPRLRTPDLERLLQLAAQCDLAVKGLRPDSLPRAPWEALQVLALSMLDALWPTPPGARQGRRLVLRPAL
>NC_014153.1|WP_013121949.1|159093_159582_-|hypothetical-protein
MKRRSVLIFAPLLALSACGFQLRGSTNLSFSTLYVAGSETSAFVVALKRQIAATTSTRIAPDAQSAQAVFTLLGESQTQTAQAYNADGTVAQYLLRYTVRFELTTPQGKVLIAPTDLSQTSNLSYNSSATLAKANESDLLYRGMRQELINRLMFQLAAVKVN
>NC_014153.1|WP_013121950.1|159582_162213_-|leucine--tRNA-ligase
MNEKYDASAVEAAAQAHWQSTDAYRVREDKPGEKFYACSMLPYPSGKLHMGHVRNYTINDMLTRHLRMNGHNVLMPMGWDAFGLPAENAAMKNKVPPAKWTYDNIAYMKRQMQAMGLAIDWSREVATCSPEYYKWNQWLFLKMLEKGIAERRTQVVNWDPVDQTVLANEQVIDGRGWRSGAVVEKREIPGYYLKITDYAEELLAAVADPEDKNYLAGWPERVRLMQENWIGKSAGVRFAFPHTIADDSGALIQDGRLYVFTTRADTIMGVTFCAVAPEHPLAAHAAAGNAELAAFIERCQQGGTTEAELALKEKEGMPTGLFVTHPLTGAQVPVWVGNYVLMSYGDGAVMGVPAHDERDFAFAKKYGLPIQQVVAVEGETFSTDAWADWYGDKQRAVCVNSGDLDGLPYKDAVDKVAELLATKDLGEKRTTWRLRDWGVSRQRYWGTPIPIIHCDHCGAVPVPEKDLPVVLPEDLIPDGSGNPLHQCAAFVDVACPQCGKPAKRETDTMDTFVDSSWYFMRYTCADNHDAMVDGRTDYWMPMDQYIGGIEHAILHLLYARFWTKVMRDLGLVKADEPFTRLLTQGMVLNHIYSRKTPQGGIEYFWPHEVENVLDAQGKIIGAKLKADGSAVDYGGVGTMSKSKNNGVDPQDLIDRYGADTARLFTMFAAPPEATLEWNDAAVEGAHRFLKRVWAFGLKLSALAAPAAEAGDAARKLRREVHQTLQQVNFDYGRMQYNTVVSGAMKLLNALEGADAAAGGMAVALREGFGILLRVLYPATPHIAHALWQELGYGAEFGDLLDAPWPQVDEAALVQDTIELMLQVNGKLRGAIQVAASADKATIEAAALASADFAKFSEGKAAKKVIVVPGRLVNVVV
>NC_014153.1|WP_081440417.1|162364_163696_+|NAD(P)/FAD-dependent-oxidoreductase
MSQTSTDSPLPRIVIVGGGAGGLELATRLGDTLGRRRQADITLIERGRSHLWKPLLHQAAAGTLGIDDNELNYLAQSTWHHFKYRLGAMDGLDRARREVLVAPTLDETGREIVPRRRIGYDILVIAVGSQNNDFGTPGAAEHAIALDTPEDSRRFHRRLVNACIAANTQVEPLRPEQLKVVAIGAGATGVELVAELHNSTRVLAAYGLDRIDPERDVRLSLVEAAPRILPALPERLSAAAAGELAKLGVQMHTGKRVTEVTATGVRTADGDFLPAELVVWAAGVKAPDFLRDIDGLETNRINQLVVRPSLQTSRDDAIYALGDCAACVWEGHAGNVPPRAQAAHQQASLIARQITRQLQGKPLLTFHYRDFGSLVSLGEHSTVGNLMGGLSKGTLFIEGHFARFIYWLLYRMHLHALHGFWKTAFLTLARMISRTTEPRIKLH
>NC_014153.1|WP_013121952.1|163797_164154_+|hypothetical-protein
MRHKSWFMAIATVAMVSTAWADNWMPVLKNTPLQRFSQADINQLSEEGAAFLGSDATLLEWRNPKSGAGGSFKLIASDTHEGRLCKTFRVTLYTPRDPAKSARLRACRQPAGEWRLVP
>NC_014153.1|WP_013121953.1|164196_165687_+|amidohydrolase-family-protein
MRKPSTPHPGAQTSPRSAFYCRCGGDEASQVQRRLERAFSRRDFLQSALVLAAGVGGLSPAASAQPAPSGSATAVAAPMVLRNVQLFDGRRTRLQPGLQVVIEGARIRAVEPQGQGAPQGAQIIDGGGRVLMPGLIDAHWHSLMAAMSMQHLLMADPALIHLAAGSEAQRTLLRGFTTVRDAGGPVFALKSAIDQGLVQGPRIFPSGAMISQTAGHGDFRFLHAVGPGAACSAVGHAEHLGASAIADSADSVRKATREQLLRGASQIKLMAGGGASSLYDPLDSVQFTLPELRAAVEAAEDWGTYVMAHVYLPKGMQRSIEAGIKVIEHGQLTDEATVRLMADKGIWWSLQPFLPEAAPTPMADPGSQAKSDEIATGTRRAYELAIKHKMQTGWGSDILFAPGKTHYQTVRLVALENWYSPLDALKQATSQNGELLALAGQRNPYLGAKLGVIEPDAWADLLVVDGDVSRSLKPLLEPDQHLKCIIKNGRVVKNTL
>NC_014153.1|WP_013121954.1|165778_166078_+|hypothetical-protein
MSMKKTDLEKHLAKKLDGKLKSGTIPQRFGQGAKAVAAKAEAKPKESAPKLVQLTCKLPADLAQRLRDRAVTVEGGVNAILAQAARQWLESAAGASRKE
>NC_014153.1|WP_013121955.1|166177_166570_+|VOC-family-protein
MFSHVMVGVANFDRAMAFYKPVLDALGVQFRFQEPERPWAGWESSPDPRPLFLIGRPYNQQPHQPGNGQMVAFLAHSREQVDQVHALALASGGTCEGKPSLRPEYHANYYGAYFRDPDGNKLCVACHQAE
>NC_014153.1|WP_013121956.1|166662_168111_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MQWEVVIGLETHVQLSTQSKMFSAASTAFGAAPNTQACAVDLALPGVLPVANRAAVERAIRLGLALGATIAPRSVFARKNYFYPDLPKGYQISQYEIPVVQGGVVEFLVDGKPHRLQLTRAHLEEDAGKSLHEAGLFDRAGNPASGIDLNRAGTPLLEVVTEPDMRSAREAAEYARALHALVMWLDICDGNLQEGSFRCDANVSVRRPGEPLGTRCEIKNLNSFRFLEKAIEFEVRRQIELIEDGGKVVQETRLYDPDKGETRTMRTKEDAHDYRYFPDPDLPPLVISPEWIERVRADMPELPGQMAARFVASHGLSLDAAAQMTQTRAHAAYFEACVAAGAAPKLAANWIMGELAAQLNRDDLDIGASPVSAAQLAALTRKIDDGTLSSKTAKEVFAALWTGEQGGDVAAIIDARGLAQVNDSAALQAAVDAVLAANPKNVEEYRAGKDKALNALVGQVMKATGGRANPQQVGEMLKKAVG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_2

423058-423159

Orphan

Consensus_repeat	Method
CGGTTTACCTCGCAAGCCCGCGCCGTTGCTTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_2

>merge|NC_014153|2|423058-423159|CRISPRCasFinder
CGGTTTACCTCGCAAGCCCGCGCCGTTGCTTGCGCTGCGGCGGTTGCGGTTTACAAAGCACAGCGCAGTCGGTTTACCTCGCAAACCCGCGCCGTTGCTTGC

>NC_014153|2|2|423058-423159|CRISPRCasFinder
CGGTTTACCTCGCAAGCCCGCGCCGTTGCTTGC	GCTGCGGCGGTTGCGGTTTACAAAGCACAGCGCAGT
CGGTTTACCTCGCAAACCCGCGCCGTTGCTTGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013122166.1\|423237_423645_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122170.1\|424857_425829_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374806
NC_014153.1\|WP_013122158.1\|414652_415876_+\|DUF4102-domain-containing-protein	unknown	unknown	gnl\|CDD\|170049
NC_014153.1\|WP_013122168.1\|423831_424080_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122163.1\|417855_418068_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122167.1\|423646_423835_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122165.1\|421115_422723_-\|type-IV-secretion-system-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|313610
NC_014153.1\|WP_013122157.1\|412241_413981_-\|type-IV-A-pilus-assembly-ATPase-PilB	unknown	unknown	gnl\|CDD\|274186
NC_014153.1\|WP_041608329.1\|422731_422965_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223221
NC_014153.1\|WP_081440373.1\|425948_426977_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|284027
NC_014153.1\|WP_081440374.1\|426963_428472_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|238545
NC_014153.1\|WP_013122160.1\|416083_416323_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122161.1\|416730_417225_-\|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl\|CDD\|225675
NC_014153.1\|WP_013122169.1\|424495_424861_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013104552.1\|429204_429960_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NC_014153.1\|WP_155816220.1\|428565_428781_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_014153.1\|WP_013122175.1\|429956_430808_+\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	unknown	unknown	gnl\|CDD\|225316
NC_014153.1\|WP_013122164.1\|418274_421112_-\|relaxase-domain-containing-protein	unknown	unknown	gnl\|CDD\|378042
NC_014153.1\|WP_155816218.1\|417284_417806_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122156.1\|411006_412227_-\|type-II-secretion-system-F-family-protein	unknown	unknown	gnl\|CDD\|224376

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013122170.1\|424857_425829_-\|hypothetical-protein	gnl\|CDD\|374806	pfam16793, RepB_primase, RepB DNA-primase from phage plasmid. RepB_primase is a DNA-primase produced by P4-like phages. It is a zinc-independent primase unlike Pri-type primases. It takes up a dumbbell shaped consisting of an N-terminal catalytic domain separated by a long alpha-helix plus tether and a C-terminal helical-bundle domain. Primases are necessary for phage replication. RepBprime primases such as in this family recognize both ssiA and ssiB, ie only 1 single-stranded primase initiation site on each strand, independently of each other and then synthesize primers that are elongated by DNA polymerase III. The phage is thus replicated exclusively in leading strand mode.	7.0993e-48
NC_014153.1\|WP_155816220.1\|428565_428781_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.68832e-05
NC_014153.1\|WP_013122158.1\|414652_415876_+\|DUF4102-domain-containing-protein	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	1.16119e-71
NC_014153.1\|WP_013122165.1\|421115_422723_-\|type-IV-secretion-system-DNA-binding-domain-containing-protein	gnl\|CDD\|313610	pfam10412, TrwB_AAD_bind, Type IV secretion-system coupling protein DNA-binding domain. The plasmid conjugative coupling protein TrwB forms hexamers from six structurally very similar protomers. This hexamer contains a central channel running from the cytosolic pole (made up by the AADs) to the membrane pole ending at the transmembrane pore shaped by 12 transmembrane helices, rendering an overall mushroom-like structure. The TrwB_AAD (all-alpha domain) domain appears to be the DNA-binding domain of the structure. TrwB, a basic integral inner-membrane nucleoside-triphosphate-binding protein, is the structural prototype for the type IV secretion system coupling proteins, a family of proteins essential for macromolecular transport between cells and export.	7.33999e-113
NC_014153.1\|WP_013122157.1\|412241_413981_-\|type-IV-A-pilus-assembly-ATPase-PilB	gnl\|CDD\|274186	TIGR02538, Type_IV_pilus_assembly_protein_PilF, type IV-A pilus assembly ATPase PilB. This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	0
NC_014153.1\|WP_041608329.1\|422731_422965_-\|hypothetical-protein	gnl\|CDD\|223221	COG0143, MetG, Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	0.000639587
NC_014153.1\|WP_081440374.1\|426963_428472_-\|AAA-family-ATPase	gnl\|CDD\|238545	cd01125, repA, Hexameric Replicative Helicase RepA. RepA is encoded by a plasmid, which is found in most Gram negative bacteria. RepA is a 5'-3' DNA helicase which can utilize ATP, GTP and CTP to a lesser extent.	8.31843e-35
NC_014153.1\|WP_013122161.1\|416730_417225_-\|glycine-zipper-2TM-domain-containing-protein	gnl\|CDD\|225675	COG3133, SlyB, Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane].	1.4226e-22
NC_014153.1\|WP_013104552.1\|429204_429960_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.72803e-130
NC_014153.1\|WP_013122175.1\|429956_430808_+\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	gnl\|CDD\|225316	COG2518, Pcm, Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones].	2.53077e-71
NC_014153.1\|WP_013122164.1\|418274_421112_-\|relaxase-domain-containing-protein	gnl\|CDD\|378042	pfam08751, TrwC, TrwC relaxase. Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.	2.53764e-88
NC_014153.1\|WP_081440373.1\|425948_426977_-\|hypothetical-protein	gnl\|CDD\|284027	pfam06504, RepC, Replication protein C (RepC). This family consists of several bacterial replication protein C (RepC) sequences.	1.19505e-17
NC_014153.1\|WP_013122156.1\|411006_412227_-\|type-II-secretion-system-F-family-protein	gnl\|CDD\|224376	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion].	3.98604e-152

>NC_014153.1|WP_041608329.1|422731_422965_-|hypothetical-protein
MQHTIAFKVGDDMHAVIKYAADQAGLSPGQYARFSALQSANLRILENRIDAVEQNIISTHREDLKKITAHIINTLKK
>NC_014153.1|WP_013122165.1|421115_422723_-|type-IV-secretion-system-DNA-binding-domain-containing-protein
MFNFRFENIWSSYLRPSFVSLGILVAGLMAVGVSGFFLKPILSAAVFVPFAYFAYKYLSKNFGAGTGSGKNINHLRGAAMVGGAELDNLVIARYGKRQTGDLHIAGIRIPREFETRGFMFAGAPGTGKSVAITSMLDIIYQRGDAAFIADRSGIYAARYYNPQRDIILNPIDARAHEWSPLAEMRSEYDSETIAKSIIPDAPGDAAEWNHYAQTILAGILLHAWRAGLNNSAITRLAQRADMAELKEILADHAGIGLLQNEKMFGSIRGILATYTIGLARLLPQAGRDGFSLSAWVHEQPAAFAFFPYLSDQMKPMRGIIAALADVYADAVLTLPPDANRRLWLVLDEFASLGRVDSMENFLTNARKHGGCSILGMQALSQVHSLYGRDNATSMLSSISTRLTLRAPDAETAEYLSRGLGDKQVVRTMRSGSRSSSKQGGSNTESWNQQIATERLVLPAEIMRTPDLVGYLQIAGDLPVGHIRLSLPPQRPDAAHAFTPRAAAPTPTPEPAPAPELTPTPDATPENENPLDGLEL
>NC_014153.1|WP_013122164.1|418274_421112_-|relaxase-domain-containing-protein
MISKSEITNPGGAAGYYTDQQSAAEYYSGEQVPSAWHGKAAEQLGLTGPVDAAALTGILQGRVIESDPETGEARERQLGRTRIDPDTGERSTEHRAGWDFTISAPKSVSVQALVHGDDRALQAHRAATTAALDYLERHGAQTRISSGNFAKTDGLAVATFEHVSSRAGDPQLHTHALIANVTTRDGRACSLSNEKLFQHRAAADAVYHNTLSRELQRAGFAVQHDSKGHVEIASYSKDALRDFSTRSAEIEAALAERGQTRADSTALSRQAAALDTRHDKELPETRAAHADRWQAQAEALSVKPAERSTATAAAARMTRSDPEAAVDKAIAHLSEREAVFGKHDLHREAARFSAGSATIEQIEKEIDRRERSGDLVQQPGHKADLYTSRDALEAERDTAKRLDAGRGEHEQIMTPREFDTALRQFEKQKGFSLSDEQRAASRQILTGDDRFQGVQGLAGTGKTTMLQFVREAAEAKGWTVAGHSNGSEQAATMERESGIKSTTTASHLIDQQKTLRDAPDRPAAPARELRIMDEASMSGQRNFRDVIKTTEQSGARTVFLGDKLQHQSVEAGRAFERAQKHMPTATLGEASIRRQTTEHMKAAVSDVLARRHGDALRKIQTVEVRPERDKLAPGATREQHRDAARADNAHLVQRIAKDYTALPADQRAKTLVITATNADRKALNNAIRAELKASGALADGKTVNALRSADMTKVEAKRAENYAPGQVVQLQQDAKRAPYAKGAQLEVVATDSRTNTLTCRDVQGREVRLDPAREKLTAYTRETREFAQGDRIRFTENHKLPTRDGEGLAVRNGQSAIVEKTRGDQITLRIGEGKTAQRIEIDAKANLKAEHNYVTTSHSAQGLTYDKVFIHHNTEGGRHGDRETYVNITRAREEATLYTQDVGKAEKQAGAELQKTAALDLQPERSPAPDRQPEPERERTLEREL
>NC_014153.1|WP_013122163.1|417855_418068_-|hypothetical-protein
MRNKIVALLAVSFAISACPRPPSSTPDQAADMSIIGEQPPPQTAPPLAELSGLGMGGLIGYFAAAHFAAC
>NC_014153.1|WP_155816218.1|417284_417806_-|hypothetical-protein
MKKTILAAALALSGIGAAQALTTQQAYDITQAAGAAGANAAPPATGIGVGSEINAPQCGTVVIGGTPEGIGGTGPTTTPTAAAPGVAGPDVRALGFAGRGIAELSALQAPTTFGPNGLGVAVGVGSYAGYGAIGASVAQQFHIDGRPAAFSIGGAMSGSGAQPVLHAGFSMGF
>NC_014153.1|WP_013122161.1|416730_417225_-|glycine-zipper-2TM-domain-containing-protein
MQNLKLTSLSVACAALLTLGGCATNSMTGTGTPQASAQGYTVSGAQSVQSVQLGTVLAVHPVVIAAQGSGLGAIGGALTGGAVGHQIGNGTGQTLASIAGALAGLVGGQALEGSASKESGLLVTVKLDDGRVLAITQASDVQLAVGERVQVLSGRDGKARVLPL
>NC_014153.1|WP_013122160.1|416083_416323_-|hypothetical-protein
MSATTLKTPRADQPAALQTIPSPLPLSDVRKNEPNLVLMSWAEWAATPRDYRLTKGTQRRVLRAHPSGGVGLYPVHITG
>NC_014153.1|WP_013122158.1|414652_415876_+|DUF4102-domain-containing-protein
MASNLLTDAALRRAKPTDKLQRLRDGDGLYLLLRPDGKRWWRFDYRYGGKDKTLSVGVYPDVTLARARQRADEIRQQLLDGIDPSIARKAKVTGVVAGEVSDSFEIIAREWHAGRAPTLSGNTSKNILLRLQNNAFPYIGQKSVRELRAPDVLDVLRRIEERGLGETARRVHQLIAQVMRYAVATGRADADPTPALRGALKPVMVRHHAAVIEPAELGAMLRAFDGYTGGVVVRTALQLQVMLFVRPGELRHMEWAELDLGGAQWRIPGEKMKMREPHIVPLPRQAVALLKDLQPFSCRSRYVFPSPRSKDRPMSENAVNVALRTLGYDRDTVTGHGFRATARTILDEKLRYRVEVIEMQLAHAVRDPLGRAYNRTKYLEERKDMMQAWADYLGKIRAGADAVNIWA
>NC_014153.1|WP_013122157.1|412241_413981_-|type-IV-A-pilus-assembly-ATPase-PilB
MSATSIAASASPPSKTLPGLAHALVQAELLPRTLVEQIHQRAQETRTSFIATLIGSGSMNAPDLAHWVSRTFSLPLLDLDAYDPTRLAAGAIDSKIIQSYKVLPLLKRGNRLVVATADPADHEAEDKIKFQSQAQIELVVVEYDKLTRIIDQAGQSASSQISALVGEDFDLGDLSDGSEAPDTKEQTAEVDDAPVVRFLQKMLIDAINMRASDLHFEPFEHFYRIRFRVDGELREIAQPPASIKEKLASRIKVISKLDIAERRVPQDGRMKLRISPEKSIDFRVSTLPTLYGEKIVMRILDSSSAKLGIDALGYEPEEREKLLRAIHRPYGMILVTGPTGSGKTVSLYSCLNILNQPGVNISTAEDPAEINLPGINQVNVNEKAGLNFANALRAFLRQDPDIIMVGEIRDLETADISIKAAQTGHLVLSTVHTNDAPTTLTRLMNMGVPAFNIASSVILITAQRLARKLCTQCKTPVDLPAQTLLEAGFREEDLDGSWKPYKAGKCNACGGTGYKGRVGIYQVMPITEEIQRIILNHGTAMDIAQQARKEGVRSLRESGLIKVKQGVTSLEEIIAVSNE
>NC_014153.1|WP_013122156.1|411006_412227_-|type-II-secretion-system-F-family-protein
MATAAARTAKEALFEWEGKDRQGKLQRGELRAGSEAIVSASLRRQGILVTKVKKRRLTSGKAIKAKDISTFTRQMSTMIKAGVPLLQSFDIVGRGHPNPNMARLIMDIRGDVETGTSLSNAFRKHPKYFDALYCNLVEAGETAGMLELVLDRLATYQEKSLAIRSKIKSALTYPIAVMVVAFVVVSIIMLFVVPVFTDVFSQFGASLPAPTLMVVAMSNFFVHYWYILFGTIFLGGYFFLQSWKKSIKMQETMDRLLLRVPVFGKLVRLGALARWTRTLATMFGAGVPLVEALDAVGGAAGNIVYLRATEKIQQDVSTGTSLTTSMQTQGVFPPLVIQLTSIGEESGSLDSMLSKAADIYEAEVDELVKNLSALLEPIIIVFLGVIIGGLVVAMYLPIFNLGKVVG
>NC_014153.1|WP_013122166.1|423237_423645_-|hypothetical-protein
MAHIVDENQAQAHSLLWRLRIILIACIAAAALIPCAYIWRMHAFEYIALYYIGAVFNAMPGIALKLGGYPQVALEFYQHYAALGGLEFMSTVFRLCIISGLLGAVLSGAYLFRRQLFRTDQPPRIAEGDDEHDPY
>NC_014153.1|WP_013122167.1|423646_423835_-|hypothetical-protein
MNPLYTVIFDAPAQYRISLDSSGEAVIPLNQREIIFLQLINQSINERLGINLPNNSHQQWSI
>NC_014153.1|WP_013122168.1|423831_424080_-|hypothetical-protein
MTIEILEPRKPLFLQIGWAEIRRYGGIKQALKFCSPDVLPDLILAVVYMQSPANAGLVADLASSLSARRRCGAENIESRDKP
>NC_014153.1|WP_013122169.1|424495_424861_-|hypothetical-protein
MNTAHPDAARQARIAALRAAVAREQRHGSQDLPAALQADLQGLRAAGLDFTILPGEPTPKPAPRPARTITAAEVAGLDARDPMRTLHQYQRAYAALGKSVPVGIVENLRAAARDQALRRQP
>NC_014153.1|WP_013122170.1|424857_425829_-|hypothetical-protein
MNINNLPPWVQAQPPAKRNALSHMLGLGDALPWATPGCALEIAARITPGTRKGAFIQIAELRESAAAADWLDALKKAGALNRRQPPEGANIYIRPLHTASHPWILVDDIPAQRAQALAAQHAGIAVQTSDDGNGQFWLLLDKSLPHTARTDIAKALAERLDGDPGAANGSQFGRLAGFQQRKGNKTGWTNVLADTTRTLMPWPADRLLALTGEAGVSRVARACPDVLSPCAAPAALPSLSPAPARPPAATGSRQRPAAGSGDQSAREFAYACHRLRAGWTPDRVQDAIAEHATSRGKRRDLQSAQRYAAATVRKAMSAVGDQP
>NC_014153.1|WP_081440373.1|425948_426977_-|hypothetical-protein
MAQSKPTPPTLTPAARAAMDARNGVARQDMAMGLASFVRPVVRGKRGWIEGVKQPWNGGTLELNGPELDAGDLGVLLSLLALALRHSVERGAEIATGGDVPGLLPAPGGRPGENRAADCDVMLLQTTLAAICREIGRDPNDGRAHAAIRKSIKRLQGFVIEARSGDRLATTHLIADTAGRSKGAGAVSVALSYRLARAVIGEGSYGRVRMGEWRELSPTAQCLYHFLACWRPGYGQCPTIGLDTIARHVWGAAPATGAVLRDRRRMLRAALSELPREEWEISEAEADRSMVRIERKNIDPQPEPVFSPTPTRVSAHAPHSEKPARISLPHERGRESPGQTPP
>NC_014153.1|WP_081440374.1|426963_428472_-|AAA-family-ATPase
MVSLCDRPAAARGTTPAAWARRGPTDCPQPRLRTPPIWRTCPPPTRWKCSRPWTPRWRRSPPPAQPQRCTAPISPSATPPRMPLRAASRSAGRSKSGASIWIWPSARCRCLTTSATTRRARNEPDLRYIQKICLRRLRRVRVQHLSPRGRRPHRRSLRGLRALAEMAQRGGKARPAPAARLRDTDPARPQSGFAGRSVRGGRAMRRCTFEQASQPLPPLDFVLPGLLAGTAGAIIGPGAVGKTILAQQIGVGAALGAEICAGAGGALFPAAPGGNVTVILGEDPPEIVLHRLQALIRGLGLTALQRELLDETLHIHSAVDEDLALLRKSPATGEYVRLEFLGRLEEICDGQRLVILDPLLFFAAGLDENSNGDMGALMRALNQLAHKTGCAILILHHVGKSGEGGGEAWEKARGASALTTSVRLQINLTPPSAAECQQYGLSEMERGFYVRVAQVKANYAPPRDAVFLHKGPGGVLSLAKLAEIDQAEPAPRGRKGGRNGAI
>NC_014153.1|WP_155816220.1|428565_428781_-|helix-turn-helix-domain-containing-protein
MSHLTPAREGLATCAEAQAYLRISRTTLWRFERQSVLVPVRIGRALRYRWSDLRALGGESAGESAQEGGAQ
>NC_014153.1|WP_013104552.1|429204_429960_+|5'/3'-nucleotidase-SurE
MRILLANDDGYLAPGLAALFDGLRAHWDVTVIAPEQNASAASNALTLNRPLSVYTASNGFRYVNGTPSDCVHIALTGLLDFRPDLVVSGVNNGANLGDDTIYSGTVAAATEGYLFGIPALAISLVEKGWGHLDTAVAVAVEVVAKLVEDLPQQAQLLNLNVPNRPLNELGGVRVTRLGKRHPSQPVVVQKNPYGDTIYWIGGAGAALDQQAGTDFDAIAQGFASLTPLQLDLTHHAQLQTCAARFETRGGA
>NC_014153.1|WP_013122175.1|429956_430808_+|protein-L-isoaspartate(D-aspartate)-O-methyltransferase
MSAGSKSPQRFVHWPARQAIDAALSKTPTTPPPARGQVVGARTVALPVPREPQTRGASQGPSRCLPRQAGLDSDAVRRGMVDKLRQSGHFDERVLQALQEVPRHHFVDPGLAAQAYLDNALPIGFEQTISKPSVVARGLDAALKALAPRANLGKVLDIGTGCGYAAAVTARVAADVYSVERIRALHDLARNNLRALRVPNLRLILGDGMLGCPQGAPFDAILSGAAALTLPQVWLDQLVVGGVLIAPIGDPQQLLLYRKRSATTFDVQPLEGAKFVPLKSGLT

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_3

533351-533447

Orphan

Consensus_repeat	Method
AGCGCTTCGCGTTCCCTTCGGATGCCCCTCCCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_3

>merge|NC_014153|3|533351-533447|CRISPRCasFinder
AGCGCTTCGCGTTCCCTTCGGATGCCCCTCCCGGCCTCCCCCACAAGTGGGGGAGGTGAGAACAGCGCTTCGCGTTCCCTCCGGATGCCCCTCCCGG

>NC_014153|3|3|533351-533447|CRISPRCasFinder
AGCGCTTCGCGTTCCCTTCGGATGCCCCTCCCGG	CCTCCCCCACAAGTGGGGGAGGTGAGAAC
AGCGCTTCGCGTTCCCTCCGGATGCCCCTCCCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013122252.1\|526180_527047_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NC_014153.1\|WP_013122264.1\|542964_543450_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122251.1\|525272_525956_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_014153.1\|WP_013122263.1\|539288_540110_-\|ATPase-AAA	unknown	unknown	gnl\|CDD\|366760
NC_014153.1\|WP_013122259.1\|535846_536080_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NC_014153.1\|WP_013122261.1\|536840_537221_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	unknown
NC_014153.1\|WP_013122249.1\|523531_524344_-\|septum-site-determining-protein-MinD	unknown	unknown	gnl\|CDD\|225447
NC_014153.1\|WP_013122250.1\|524362_525178_-\|septum-site-determining-protein-MinC	unknown	unknown	gnl\|CDD\|234994
NC_014153.1\|WP_013122262.1\|537222_538539_+\|type-II-toxin-antitoxin-system-HipA-family-toxin	unknown	unknown	gnl\|CDD\|377920
NC_014153.1\|WP_013122254.1\|528757_530593_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NC_014153.1\|WP_013122248.1\|520772_523208_+\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	unknown	unknown	gnl\|CDD\|274168
NC_014153.1\|WP_041608340.1\|542227_542503_+\|RES-family-NAD+-phosphorylase	unknown	unknown	gnl\|CDD\|378053
NC_014153.1\|WP_155816230.1\|543456_545298_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NC_014153.1\|WP_013122255.1\|530589_532098_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|275034
NC_014153.1\|WP_013122253.1\|527057_528536_-\|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl\|CDD\|223732
NC_014153.1\|WP_013104679.1\|523259_523517_-\|cell-division-topological-specificity-factor-MinE	unknown	unknown	gnl\|CDD\|184442
NC_014153.1\|WP_081440378.1\|535244_535739_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_014153.1\|WP_013122258.1\|534427_534628_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_155816312.1\|532094_532718_-\|sugar-O-acyltransferase	unknown	unknown	gnl\|CDD\|100050
NC_014153.1\|WP_041608338.1\|536076_536367_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	unknown	unknown	gnl\|CDD\|379750

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013122252.1\|526180_527047_-\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	8.36437e-16
NC_014153.1\|WP_013122251.1\|525272_525956_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.37562e-96
NC_014153.1\|WP_013122263.1\|539288_540110_-\|ATPase-AAA	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	1.23292e-74
NC_014153.1\|WP_013122259.1\|535846_536080_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	9.41285e-15
NC_014153.1\|WP_155816230.1\|543456_545298_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.98419e-31
NC_014153.1\|WP_013122249.1\|523531_524344_-\|septum-site-determining-protein-MinD	gnl\|CDD\|225447	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning].	6.03271e-165
NC_014153.1\|WP_013122250.1\|524362_525178_-\|septum-site-determining-protein-MinC	gnl\|CDD\|234994	PRK01973, PRK01973, septum site-determining protein MinC.	5.63237e-133
NC_014153.1\|WP_013122262.1\|537222_538539_+\|type-II-toxin-antitoxin-system-HipA-family-toxin	gnl\|CDD\|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	5.41971e-51
NC_014153.1\|WP_013122254.1\|528757_530593_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NC_014153.1\|WP_013122248.1\|520772_523208_+\|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase	gnl\|CDD\|274168	TIGR02504, ribonucleotide_reductase, ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. This model represents a group of adenosylcobalamin(B12)-dependent ribonucleotide reductases (Class II RNRs) related to the characterized species from Pyrococcus, Thermoplasma, Corynebacterium, and Deinococcus. RNR's are responsible for the conversion of the ribose sugar of RNA into the deoxyribose sugar of DNA. This is the rate-limiting step of DNA biosynthesis. This model identifies genes in a wide range of deeply branching bacteria. All are structurally related to the class I (non-heme iron dependent) RNRs. In most species this gene is known as NrdJ, while in mycobacteria it is called NrdZ. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	0
NC_014153.1\|WP_041608340.1\|542227_542503_+\|RES-family-NAD+-phosphorylase	gnl\|CDD\|378053	pfam08808, RES, RES domain. This presumed domain contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. The domain is found widely distributed in bacteria. The domain is about 150 residues in length.	0.000123661
NC_014153.1\|WP_013122255.1\|530589_532098_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|275034	TIGR04181, DegT/DnrJ/EryC1/StrS_aminotransferase, aminotransferase, LLPSF_NHT_00031 family. This clade of aminotransferases is a member of the pfam01041 (DegT/DnrJ/EryC1/StrS) superfamily. The family is named after the instance in Leptospira interrogans serovar Lai, str. 56601, where it is the 31st gene in the 91-gene lipopolysaccharide biosynthesis locus. Members of this family are generally found within a subcluster of seven or more genes including an epimerase/dehydratase, four genes homologous to the elements of the neuraminic (sialic) acid biosynthesis cluster (NeuABCD) and a nucleotidyl transferase. Together it is very likely that these enzymes direct the biosynthesis of a nine-carbon sugar analogous to CMP-neuraminic acid. These seven genes form the core of the cassette, although they are often accompanied by additional genes that may further modify the product sugar.	1.40964e-147
NC_014153.1\|WP_013122253.1\|527057_528536_-\|SulP-family-inorganic-anion-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	5.95221e-135
NC_014153.1\|WP_013104679.1\|523259_523517_-\|cell-division-topological-specificity-factor-MinE	gnl\|CDD\|184442	PRK13989, PRK13989, cell division topological specificity factor MinE; Provisional.	5.24613e-47
NC_014153.1\|WP_081440378.1\|535244_535739_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.23037e-08
NC_014153.1\|WP_155816312.1\|532094_532718_-\|sugar-O-acyltransferase	gnl\|CDD\|100050	cd03360, LbH_AT_putative, Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes showing acyltransferase activity. A few members are identified as NeuD, a sialic acid (Sia) O-acetyltransferase that is required for Sia synthesis and surface polysaccharide sialylation.	8.17551e-56
NC_014153.1\|WP_041608338.1\|536076_536367_+\|type-II-toxin-antitoxin-system-YafQ-family-toxin	gnl\|CDD\|379750	pfam15738, YafQ_toxin, Bacterial toxin of type II toxin-antitoxin system, YafQ. YafQ is a family of bacterial toxin ribonucleases of type II toxin-antitoxin systems. The E.coli gene is expressed from the dinB operon. The cognate antitoxin for the E. coli protein is DinJ, in family RelB_antitoxin, pfam02604.	2.24756e-33

>NC_014153.1|WP_155816312.1|532094_532718_-|sugar-O-acyltransferase
MIVFGAGGHGRVAADAALLSGAFARVVASDRNPATWGSELLPGVPVLSIDEASALPGPRAVHVAIGHNAIRRDEAARLASIGPLATIVHPSASVAASARVQPGCLITAQCVVAPMAELGMGVIVNHGAVVDHDCRIAAWAHVAPGVRLGGAVQVGEAALVGAGSTVLRNLRVGAGATLGAGAVLLQDLPDGEAWAGVPARPLQGVSA
>NC_014153.1|WP_013122255.1|530589_532098_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MNLNTFNALCLPPGATLHEALARLDATAQGILLVTDAQERLLRTVTDGDLRRAALAGVSNEAPLSALPAHPPHTVGLQASQRDVLALMDAQRIDHVPVVDAAGHVVDLVTRRELSQRVYLSSPHLGEDEVALVQEAFTSNWIAPLGPHVDAFERELAARVGVQHAAATSSGTAALHLGLRLLGVGPGDVVLCSSLTFVASANPIKQLGATPVFIDSEPQSWNLSPQALAVALAALQAEGITPKAAVVVNLYGQSAEMDEIVPLLERYGVPMLEDAAESLGATYRDRPSGSFGKLAVFSFNGNKIITTSGGGMLVSNDATLIEHARKLSTQAREPARHYEHIEDGYNYRLSNVLAGIGRGQLRVLEQRVQSRREVFAQYRDALSGVPGLRWMAEPEGHQSTRWLSAFVLAGGDGESPQARRDALLDFLERHNVEARPVWKPMHLQPLYAACRYFLHAPGQDVSRALFEGGVCLPSGSNMSAAQRARVCELVAHGLELSWRSAA
>NC_014153.1|WP_013122254.1|528757_530593_-|polysaccharide-biosynthesis-protein
MRFSTRAIWRPAAADALLVALTWQLAFLFRFSLLRNDAPVNLAQILWISTPLAAVVWVAALAGLGVYRTPWRHTSVPEFKRLASAMIVAALALAAVLLLLRLPNFPRSIVLLHPLFAGAALLGLRLGARILAEGRLTRSTAQGKPLLVLGTLDEAARALQSLRSSKGWQVAALISPNRGEVGRSVQGVRVAGSVDDLARVAQAQGASHALIASEPGSPARRELLLQASDAHLALLTLPRADDWLQSGSSAGGGQAPRQVELADLLGRAAVQLDVRGLSSLLAGQVALVTGAGGSIGSELCRQIARFGVRQLVCIDSSEIAIYALEQEFKARFPELAVRYYTANVREPERLFDLFKRHRPAVVLHAAAYKHVPLMEDDNAIEALRTNVLGTLGAARAATASGAQRFVLISTDKAVNPTNVMGASKRLAELALQAHAAQHPDTHCCAVRFGNVLGSSGSVVPRFAAQIAAGGPVTVTHPEIVRYFMTIPEAAQLVLQAGLMGESGNIFVLDMGEPVKIVDLARLMIRLSNKTEEEIPIHFTGLRPGEKLFEELLADDETTLPTPHPKLRVARQAEQDPIDLQALELWIAASGAQSPAQIKAALHALVPEYTPQ
>NC_014153.1|WP_013122253.1|527057_528536_-|SulP-family-inorganic-anion-transporter
MMQTFRQDWLSNIRNDLLSGVVVALALIPEAIAFSIIAGVDPKVGLYAAFSMATVIAFAGGRPGMVSAATGAMALVMVSLVKEHGLQYMLAATLLTGVLQMIIGWAGFDRLMRFVSRSVITGFANALAILIFLAQLPELIRVPWAVYPLVAAGLAIIYLLPRITRVVPSPLVAIVVLTIVTAAFGIHVPTVGDKGQLPDSLPVFLLPDVPLNFETLRIIFPVSLAMAVVGLLESMMTATLIDDFTDTSSNKRRECVGQGVANIATGFLGGMAGCAMIGQSVINVKSGGRGRLSTLTAGVVLLVMVVFLGDWVARIPMAALVAVMIMVSIGTFNWGSIRNLREHPKSSSVVMLATVAVVVATDNLALGVLTGVLLSGFFFAHKVGSILRVSSRADAEGRSRTYTVTGQVFFASADAFISRFDFKEVIDKVHIDVSRAHFWDITAISALDKVILKFRREATEVEVTGLNEASATLVDKFAVHDKDGAEDLLMSH
>NC_014153.1|WP_013122252.1|526180_527047_-|universal-stress-protein
MPDHNKVTACVDHSRFADYVTDYGAWAAQRMGTLLDLLHVLDRHPETAASSSDHSGAIGLGAQDDLLQELAESERQTLLSARERGRTLLARLRQRALDAGAAEVDIRQRLGELTQTLVEQAPAIGLLVLGRRGASAEQSGRDIGRHVEAIVRALHIPILTVTDAFTPPQRVLIAYDGGSMTRRAVEWVGAQPLLAGLDTTVCMASTPSAQTEKALDWARQTLQSRGMTAQALARAGDPESVISAVLKERNIDLLIMGAYSHSPVRKLLLGSKTADLLRASTIPTLLLR
>NC_014153.1|WP_013122251.1|525272_525956_-|ABC-transporter-ATP-binding-protein
MSTPPILLAEHLRKRYTEGPQAVDVLKDVNLRLDGGQTLAIIGASGSGKSTLMHLLGGLDRADGGRVQVCGSDWAQMSPKAQGAWRNQHVGFVYQFHHLLMEFSALDNVAMPLRIRRTTAEAAHAVAAQMLQSMGLGARLQHRPGELSGGERQRVAIARALVTQPQLVLADEPTGNLDSEASAVALNLLLDVALAQGDAVIIVTHDATVAARCQRQLRLVNGALQDA
>NC_014153.1|WP_013122250.1|524362_525178_-|septum-site-determining-protein-MinC
MSRSKTTLFELRSGAIDAVHLVVKTPDFAALAEALQQRFDAAPEFFSGEAVAIDLRRLADDATLPLDELAALLRRFKMRPFGVVAQAAQQTWAGASDLPLLDSRDVGRDPRKPAESAEAAEAATAPATTAADVAPGAEPQAAAQPSVPGATPAQEPAPATLPTVLIDRPLRSGQRIYSPGDLIVQGVVSHGAEVMAEGHVHIYGALRGRALAGARGNTAARIFCTSFEPELVAIAGIYRTAEQDFPAGVRGKPTTVRLQGEQLLIEPLALK
>NC_014153.1|WP_013122249.1|523531_524344_-|septum-site-determining-protein-MinD
MAKIIVVTSGKGGVGKTTTSASFASGLALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIQGEAKLTQALIKDKQCDNLFILPASQTRDKDALTMEGVENVLKELDDMGFTYIVCDSPAGIESGALMAMHFADEALIVTNPEVSSVRDSDRILGMLSSKTKRAIEGGEPIREHLLITRYNPKRVSDGEMLSLTDIQDILRIQLIGVIPESESVLQASNQGTPAIHLTGSDVAEAYQDVVARFLGEDKPMRFTDYQKPGLFKRLFGG
>NC_014153.1|WP_013104679.1|523259_523517_-|cell-division-topological-specificity-factor-MinE
MSFLSFFLGEKKKTATVAKERLQIILAHERGGNGAPADWLPALQRELVDVISKYVKIDSNDIQVKLERQDTLDVLEVKIEIPPRG
>NC_014153.1|WP_013122248.1|520772_523208_+|adenosylcobalamin-dependent-ribonucleoside-diphosphate-reductase
MQAQDISLDVLAEKYAKGDEHTIADIHTRVARALAVEEADPARSEALFRQALADGFVPAGRIMSAAGTDIQATLINCFVQPVGDSVSDDKDGKPSIYKALAQAAETMRRGGGVGYDFSRIRPAGAHVGGTHSRASGPLSFMRVFDASCETVESAGSRRGAQMGVLRADHPDIEAFIHAKDQGAFKNFNLSVGVSAAFMQAVENDAQIDLVHKARPGDDQLAAGARQRADGLWVYRSVRARDLWDQIMQSTYDHAEPGILFLDTANADNNLYYCETFEATNPCAEEFLPDYGCCCLGSINLTRFVRDPFTPQARFDAEGFQAVTRVAVRMLDNVLDVTYWPLVEQHNEAQNKRRIGLGFLGLGDACVMLGLRYDSDDARRFAADMARTLRDAAYAASVDLAKEKGAFPLFDAKKYLDSGFAKRLPEALRADIAAHGIRNSHLLAVAPTGTISLAFADNASNGIEPAFSWVYTRKKRMADNTTREYEVADHAWRLYRSMGRDMSALPPAFVTALEMSAADHMKMLQVVQPFIDTSISKTVNVPADYPYDDFKDLYLQAWKAGLKGLATYRPNAVLGAVLQATPTAAAPAAASAQTADDIDPLTRRIEGRPSGDLQAVTSKISYMTSEGQKTVYLSVSFAEVEGRVNGEAVRIERPIEFFMPAGQRDEGQQWIASNMRLLSLVARSGGSIAKSLQNMREVVWDKGPVRCGEVIKSDGSRAPRFHQSEVAAIAYALQELLRRRGYLDASGREQSLLSLAQRAHVPEALRIDLESADASPELLPGGRICPECGGPFLRRVDGCDRCENCGYIGSCG
>NC_014153.1|WP_013122258.1|534427_534628_+|hypothetical-protein
MDMIGKIQRMHFRQNKSARVIARSTGLSRNTVRTWLRQPGDVVSRYAVVLGAACGGDTVGGTIGDI
>NC_014153.1|WP_081440378.1|535244_535739_-|helix-turn-helix-domain-containing-protein
MCRRRQHVGSTPCHTTIRRALLRTSVSTQIPQNQRSNFMTDMTPQPETIAHTFQPLSKSDVARALGVCVRTVESWVNAGEIPPPAKIGARVYWHPRTFYAWLDKRLQVSAPIEVTDATHPDTAKAPHRTATPVRQARARSAPKSSAAARAQERSTRLLAELNAD
>NC_014153.1|WP_013122259.1|535846_536080_+|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MLTADVRSRVESELKREAAAVLKAAGLDVSTAIRLFLRSVVEKGGLPMELPRANPVTLAAIRNAKAGKTTRTSLEDL
>NC_014153.1|WP_041608338.1|536076_536367_+|type-II-toxin-antitoxin-system-YafQ-family-toxin
MSAPRTLGETSQFKRDKKRIKGSGRYDWEAMRDVVKELMNDRPLDPRHRDHELSGEYAGVRECHVALDWLLIYDKEGPLKGGSLRLIRTGSHSELF
>NC_014153.1|WP_013122261.1|536840_537221_+|helix-turn-helix-domain-containing-protein
MPKTARALLQLPPATAGAIEKLGADLAVARLRRKESLRSWAQRLGVSVPTLQRLEAGDPSVGIGIVATALWLIQRDGELRNLAAPEHDQGALEMDVREAIELGRARAQASAEARLHAVVPSVKTKN
>NC_014153.1|WP_013122262.1|537222_538539_+|type-II-toxin-antitoxin-system-HipA-family-toxin
MRLDDLSLWYLGDPAAPRYVGALRLVSAGKGVSLRYGRDWLASGFALSEDLPLIDNEFMPPGRLSTDAQRAVGAVDDARPDRWGEKVIRFVDKPKRLSLMEYLYYAGDDRFGALGVSTSPDTYSPRAGSPLPRLEQAQQLSDVVAKIEASEPLSVLETKMIAGGGSPLGGAKPKALIDIGGEQWVIKFFNNEPVDTPLIEHASMTLAKRAGITVAETQVIRLADANAIAIRRFDRVQRRRIHSISAGTAIRAATASGDEPEMGYPELARILRRVGITQDDTYQRDARELFRRMVFNILMDNTDDHEKNHALLVVNPFANGRLKLAPAYDVLPSNSGQGYQEFVCGAHGRESTLDNAMSQCEAFGLLPAQAAAEVVGVIDVVNTWQEHFVQTGVTRHDIESLAERIDGTELLKQRIRFDQTQFQSAPTKRKKPGPFQRN
>NC_014153.1|WP_013122263.1|539288_540110_-|ATPase-AAA
MKTDVLVELKALRLHGMAGAWADLVEQGGGEGGGVGVESSRWLIEHLLQAEGTDRAMRSVSHQMHAAKFPVHRDMAGFDFEVSPVDRKLVETLATTAFTDAAHNVVLVGGPGTGKTHLATAMGVSGITRHGKRVRFYSTVDLVNALEQEKAQGKAGRIATSLLRMDLVILDELGYLPFSQAGGALLFHLLSKLYEHTSVMITTNLDFAEWSSVFGDAKMTTALLDRLTHHCHIVETGNESIRFSRSTAAAKKRIKAREQARKGVSTQAEPDPF
>NC_014153.1|WP_041608340.1|542227_542503_+|RES-family-NAD+-phosphorylase
MESCPPWRGIRTLGLNNDISAGSDYTASMAWAKAIHEADPKWDGIRYVSRQHNDRYAVALFERSGITRARTYKLAGKALGALCDEYHVTAI
>NC_014153.1|WP_013122264.1|542964_543450_-|hypothetical-protein
MTSMQKNALGTLSSQYNLRVLRLNRQRRLPSVETQTVAFVEFARQGGEIMSTWVEWAGFAVYLRYAPSRRLTDSLEVGECIAISTIHIPDRLQHRGWFWRYCQLCLGLVEDALVLEGVVNPSLRASLRQRPEFFEFHDESFVLRRLPDHRWPLRVFPDLNV
>NC_014153.1|WP_155816230.1|543456_545298_-|tyrosine-type-recombinase/integrase
MEIKNLDSSWAGSRGIAPSMCKMCKCRSFEKTRQFSPFLRQFTLRRVSRACVEFTKTALERRRIGDLKSSGGDYAAACFTAIDAYTGFHPLLRNPIMSDISNRSAYRVTVARRPEHDRTFPFSQAGRTKLAAYIAELRAKGLKPQVAQGTDAWQVRVRRKGHPAQVTTFGSLEEADAFVKTIDAEQSRGLFRDYTAAANISFAALVQRYIDEECPRLKGGDTYAIILNAMLEDSVGALDQRIRVREAEAKACGRPMTKLRANRVPMGNLEWMQKPMTEIQAMDIEDFIQERLQYVAPPTVDRQLDLVRAVIKVATETWGYYVDRNPLQGVRLPKYFNERERRLSEDEEVRLLEAARQEDQLRSFDQQVKAAASNTVMQSKTLPTHYARNAASREAYESARAQVLQSGFQHVPVLEAFIRFQLATAARRGETLGLRWTDIDAKSQTALLPTTKNGRARRLALRIDVLELLQQLPRTSDRVFDLSIKALANAWRKMCDSSSIEDFRIHDLRHEAISRAAESGVFATVLDLQAFSGHRDLRSLTRYTHLQASAIAKKLESAEAARLAAHKGRLRLKSSEMNLLLTSAPSPTFRDTDVDLCTAPNVVQFPKHHSVAR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_4

1967896-1968021

Orphan

Consensus_repeat	Method
CCCCAAGTTTCCTTGACCCCCTCGGGGGGCGGGCTGGGCGAAGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_4

>merge|NC_014153|4|1967896-1968021|CRISPRCasFinder
CCCCAAGTTTCCTTGACCCCCTCGGGGGGCGGGCTGGGCGAAGCCCGGCCCTGGGGCGCTCTCAAGAAAACGCCGGGCCGCCCCAAGTTTTCTTGACCCCCTCGGGGGGCGGGCTGGGCGAAGCCC

>NC_014153|4|4|1967896-1968021|CRISPRCasFinder
CCCCAAGTTTCCTTGACCCCCTCGGGGGGCGGGCTGGGCGAAGCCC	GGCCCTGGGGCGCTCTCAAGAAAACGCCGGGCCG
CCCCAAGTTTTCTTGACCCCCTCGGGGGGCGGGCTGGGCGAAGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013123444.1\|1977004_1980289_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_014153.1\|WP_041608417.1\|1969573_1972384_+\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|234570
NC_014153.1\|WP_013123446.1\|1980966_1982307_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|182388
NC_014153.1\|WP_041608654.1\|1960465_1961068_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NC_014153.1\|WP_013123440.1\|1973474_1973810_+\|peptidase-M4	unknown	unknown	gnl\|CDD\|377032
NC_014153.1\|WP_049774666.1\|1961086_1962505_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NC_014153.1\|WP_013123431.1\|1959490_1959955_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319917
NC_014153.1\|WP_013123441.1\|1973899_1974517_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|183335
NC_014153.1\|WP_013123443.1\|1975937_1977008_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_014153.1\|WP_013123435.1\|1963845_1964019_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_041608415.1\|1966214_1967366_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235899
NC_014153.1\|WP_013106215.1\|1968422_1969376_-\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NC_014153.1\|WP_013123436.1\|1964035_1964938_-\|cysteine-synthase-CysM	unknown	unknown	gnl\|CDD\|236972
NC_014153.1\|WP_013123429.1\|1957479_1958028_+\|arsenate-reductase-ArsC	unknown	unknown	gnl\|CDD\|319973
NC_014153.1\|WP_013123439.1\|1972390_1973371_-\|patatin	unknown	unknown	gnl\|CDD\|132866
NC_014153.1\|WP_013123442.1\|1974513_1975941_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NC_014153.1\|WP_013123430.1\|1958114_1959416_+\|arsenic-transporter	unknown	unknown	gnl\|CDD\|185342
NC_014153.1\|WP_013123434.1\|1962560_1963673_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_014153.1\|WP_013123445.1\|1980292_1980970_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_014153.1\|WP_013123437.1\|1964991_1966215_-\|heme-biosynthesis-protein-HemY	unknown	unknown	gnl\|CDD\|273126

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013123444.1\|1977004_1980289_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_014153.1\|WP_041608417.1\|1969573_1972384_+\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NC_014153.1\|WP_013123446.1\|1980966_1982307_+\|HAMP-domain-containing-protein	gnl\|CDD\|182388	PRK10337, PRK10337, sensor protein QseC; Provisional.	4.57786e-65
NC_014153.1\|WP_041608654.1\|1960465_1961068_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	5.35296e-64
NC_014153.1\|WP_013123440.1\|1973474_1973810_+\|peptidase-M4	gnl\|CDD\|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	1.07019e-07
NC_014153.1\|WP_049774666.1\|1961086_1962505_-\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.05378e-58
NC_014153.1\|WP_013123431.1\|1959490_1959955_+\|glyoxalase	gnl\|CDD\|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.05169e-46
NC_014153.1\|WP_013123441.1\|1973899_1974517_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|183335	PRK11837, PRK11837, undecaprenyl pyrophosphate phosphatase; Provisional.	7.58918e-45
NC_014153.1\|WP_013123443.1\|1975937_1977008_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.45078e-37
NC_014153.1\|WP_041608415.1\|1966214_1967366_-\|hypothetical-protein	gnl\|CDD\|235899	PRK06975, PRK06975, bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed.	1.77142e-66
NC_014153.1\|WP_013106215.1\|1968422_1969376_-\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	1.57776e-167
NC_014153.1\|WP_013123436.1\|1964035_1964938_-\|cysteine-synthase-CysM	gnl\|CDD\|236972	PRK11761, cysM, cysteine synthase CysM.	0
NC_014153.1\|WP_013123429.1\|1957479_1958028_+\|arsenate-reductase-ArsC	gnl\|CDD\|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	3.31705e-74
NC_014153.1\|WP_013123439.1\|1972390_1973371_-\|patatin	gnl\|CDD\|132866	cd07228, Pat_NTE_like_bacteria, Bacterial patatin-like phospholipase domain containing protein 6. Bacterial patatin-like phospholipase domain containing protein 6. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. This group includes YCHK and rssA from Escherichia coli as well as Ylbk from Bacillus amyloliquefaciens.	5.74309e-79
NC_014153.1\|WP_013123442.1\|1974513_1975941_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.00793e-16
NC_014153.1\|WP_013123430.1\|1958114_1959416_+\|arsenic-transporter	gnl\|CDD\|185342	PRK15445, PRK15445, arsenical efflux pump membrane protein ArsB.	0
NC_014153.1\|WP_013123434.1\|1962560_1963673_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	1.63566e-19
NC_014153.1\|WP_013123445.1\|1980292_1980970_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.38734e-74
NC_014153.1\|WP_013123437.1\|1964991_1966215_-\|heme-biosynthesis-protein-HemY	gnl\|CDD\|273126	TIGR00540, TPR_hemY_coli, heme biosynthesis-associated TPR protein. Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General].	3.69266e-71

>NC_014153.1|WP_041608415.1|1966214_1967366_-|hypothetical-protein
MTEPSTLPEAEPSPAQAPAAAQVAASVANSPEPAALPPSAELSQPAPVGLPGARWVWPVLVALVVALVAMAWWLNNRLYATQAEIAQRLQTATTDAIEAKTLTKQASDSVRDLTTRLAVLESRQQDFAAQRQALETLYADFAKTRDQARLSETGQLIALAQQQAQLIGNVQPLIATLQSADARLARSPNPKAQILRRAVQSDLTRLRSAVTPDIAAAAHKLNDLAALVDSLRLVSAAGAAHGASAPGTPPVAPASAAGPRWAPWLGDWFERFRASLVQLFGITRVGSRDALLASPQQGEFLRENLKLRILNARLDLLSRNAVAYRSDMRGIDEALKTYFDKRQPRMVQALSLARQAAQLDLSANPAANLESLAVLSTLDSGAP
>NC_014153.1|WP_013123437.1|1964991_1966215_-|heme-biosynthesis-protein-HemY
MRWLIWVLILAAAAVLLALGTTLNTGNVALLLPPWRVDVSLNFAVLLLLLAFVVFYLVLRGLSLLLGMPQAAAEFRARRRMRLAAQALHNGMFDYFGGRFRRAERAAQRAAEFADFAPAALMTAAQSAQQLQAYDRRDAYLEQLPQPARDAGALLKAQWQLDAKQPREALAQLRALPAGVQRRTHALRIELQAARKVGDHAAVLRLARTLLKHGALHPAAAQAMLHTAATGLLRQAGDDPQALRTTWHRLTAQERTDPTLVIAAARGFAAAGEVGEARQLLIDALNRPQAEPGLFMPSLRAMLTGIDAGFVAQTEQWLGRWPQEAQAYFTAGAACAEMQLWGKAQQHLQKAIQSCSDDERRLRGQIHAALAQLLEGIEREDQAQRHWREAAMDLCALDLPGKANERI
>NC_014153.1|WP_013123436.1|1964035_1964938_-|cysteine-synthase-CysM
MSYLTIDQVIGNTPLVQLQRIPGADNARRGNLILGKLEGNNPAGSVKDRAAISMIRHAQERGAIKPGDTLIEATSGNTGIALAMAAAILGYRMVLIMPEDLSIERAQTMKAFGAELLLTPKSGGMEYARDLAEQMQRDGKGLLLDQFANADNPRAHFETTGPEIWRDTKGRITHFVSAMGTTGTITGVSHFLKEQNPAVQIIGAQPEEGSRIPGIRKWPQEYLPKIYEPQRVDRLEYVSQAAAENMARKLAREEGLFCGISAAGACEVALRIAREVENATIVFIVCDRGDRYLSTGVFPA
>NC_014153.1|WP_013123435.1|1963845_1964019_+|hypothetical-protein
MGTKIYLTGLGILLIVCLSVGFYMGYSHVFAPGAYSVPDQGIAQTPAPSASATAAQN
>NC_014153.1|WP_013123434.1|1962560_1963673_-|DMT-family-transporter
MPSSLTPPSQNASLHQGITLSLVAALLFGASTPLAKLLLADTSPWLLAALLYLGSGIGLAVWRALRAVRSGEAATSHLQAGEWPWLAAAIFSGGVAAPVLLMFGLSRMPAAGASLLLNLESVLTALLAWFVFRENFDRRIALGMGAIVLGSVVLNWPGQGMRLDWSSLWPGLAVIGACLGWALDNNFTRKVALADASFVAMSKGLIAGAVNLLLAMLVGAQWPTWPIVLAAGALGFASYGVSLVLFVLALRHLGTARTSAYFAVAPFFGAALAVLLLGEALTLGLVLAGGLMALGVWLHVSERHAHAHDHEAMHHSHRHVHGGPKDDGHHDHVHEPPVPIGTQHSHPHDHAPLRHTHAHFPDAHHRHRHG
>NC_014153.1|WP_049774666.1|1961086_1962505_-|diguanylate-cyclase
MLRSEVARQSERQVIPGLRNATLRDVLAGRYIMAFAEQGGLPSLEILFEHMADAVYLLDPVTSNILWCNRAAYADLGLQASEVLHHSVLSLQKDVQGLPQWADIAQVIRTADCYTFVGRHRHQDGGEIPVEVNTTHFNHQGRDYFLSVARNISKRLSLDEASSTRDERLSFALEQAMDGLWDWNLLTDAVYFSPQLKRMLGYGPDEMTPHVETWKHNVHPDDRDQVMSLIDQHLRGRLMRFEAEYRLRNRNGHDIWVHDRGQVCERDAQGRPTRMVGMVQNITDRKLLELRLEKMASIDDLTQIPNRRAGMAALAQQIALSERSGGALSVGVLDIDAFKSVNDRFGHAVGDEVLHQVARLLRQTLRPGDLVYRSGGEEFVLILPAAGRETADAIAADIHAAFAAKDWEGDLSVPGVTVSIGLASYPQDQPQLHKLLDQADLALYRAKESGRNRTCRAGDLLAAPAPSASMID
>NC_014153.1|WP_041608654.1|1960465_1961068_+|amino-acid-transporter
MHAYLSGFALGLSLIVAIGAQNAFVLKQGLKGEHIFWVVMVCALSDALLIGIGVSGFHVLVARAPWLTTLSRYAGAAFLLWYGARSFRAALRSAAVLAPAGGGASPLGKTLATVLAFTFLNPHVYLDTVVLLGSVSTQFPGRTAAFGAGAASASFVFFFALGYGARLLRPVFARPFTWKVLDVLIGLTMAALALKLLLGG
>NC_014153.1|WP_013123431.1|1959490_1959955_+|glyoxalase
MTSSPAFPAAHEFHMSLRVADLARSTAFYTAFFGLPPKDRTARYSTFIVPHLHLNLVLLVNDRGEALDTYSLYHLGLGVAGKAEVIAAYHAAVAAGAEIVKPPRTTWRGTPLHELWLRDPSGYLLEVYARLTDAELAQMPADMEPLFLLDSPQA
>NC_014153.1|WP_013123430.1|1958114_1959416_+|arsenic-transporter
MIAALLIFILTLVFVIWQPRGLGIGYSALGGAAIALMFGVINWGDIPVVWHIVWDATFTFVGLIIISLILDDAGVFHWAALHVARWGGGRGRRLFPLIVVLGAVISAFFANDGAALILTPIVLAMLLALGFGPAAALAFVMACGFVADTTSMPLVISNLVNIVTAGYFNIPFDRYAAVMVPVDLAALAATLVVLMLFFRRDIPAGYDLARLDAPSSAIKDALVFRWTWPVMAVLLVAYFVTAAWQVPVSLVTGIAALLLLALAGRWWRGGRGAVIDLRHVIKGAPWQIVLFSLGMYLVVYGLRNAGLTDYLALALEALARHGTVVAVVGTGFISAVLSSVMNNMPMTLVGALGIHHAQGIDPAVREAMIYAHVIGCDLGPKFTPIGSLATLLWLHVLDRKGVHIGWGYYMRIGLALTTPVLLITLLALAWRLG
>NC_014153.1|WP_013123429.1|1957479_1958028_+|arsenate-reductase-ArsC
MDKVYNVLVLCTGNSARSIMGEGLINTLGKGRFKAYSAGSHPGGVVNPYAIEQLKSIGYPTDTLRSKSWDEFATPDAPQMDFVFTVCDKAAGETCPIWPGHPMTAHWGFEDPAAVEGSDEEKRRAFQTIFRQIMCRVRAFVSLPLDRLDAAAIKREIVDIGKTQVMPLPESCAKDDLDPVVQ
>NC_014153.1|WP_013106215.1|1968422_1969376_-|hydroxymethylbilane-synthase
MTSTFTPPPSLVIATRESRLALWQAEHVRDLLKGLYPQCDVRIFGMTTQGDQILDKSLAKIGGKGLFVKELEVAMEQGHADLAVHSLKDVPMVLPTGFALTAVMEREDPRDAWVSPHYANLADLPAGAVVGTSSLRRESQLRARYPHLKVQALRGNLDTRLRKLDEGQYAGILLAAAGLKRLGLGERVRAVIEPEDMLPAVGQAALGIEIRADRPDLAQALAALNHPPTALCTHAERAVSRGLGGSCTTPMGAYATLEGEAMHLRAVLGLPDGSQALHAQQRGRVTDLAQAEALGQQVARQLREQGADALLAQLGSH
>NC_014153.1|WP_041608417.1|1969573_1972384_+|phosphoenolpyruvate-carboxylase
MSTRPSAARNASDPDAPLFDDIRLLGRLLGDLIREQEGQEMFDIVETVRQLSVKFHRDGDAKDRRALDKLLSSLSRDQAVSVIRAFSYFSILANIAEDHHVLRRAEQDAERGAPPQRDSVRAALETLKDSGVDRQQLLQFFDQALISPVLTAHPTEVQRKSVLDAERALARLLVERDATRLPQKRADIEDAMRARVVQLWQTRLLRYVKLKVSDEIKNALSFYGATFFSQFPRLYRNLERDIEALFPAGGQDLAKTDLPAFFRMGHWIGGDRDGNPFVTADTLSYALRMQSRTAIEFYMAEVHAIGGELSISALLASASPELMALAEQSPDLSEHRSDEPYRRALIGMYARLAANLRKLAGVQALLPEVGSAEPYANADEFIADLRIIHDSLHRHHAGPLAQTRLDPLIRAAGVFGFRLATIDLRQSSDQHEAVLRELLAAAGLCPDYSHQDEAAKQALLIRCLNDPRPLRLPHHVYSDWARSELAVFDRAYSARRDFGPRAIRQYIISHSETVSDLLELLLLQKEAGLFHGTLGSHDSYAELLVAPLFETIEDLRNAPAIMRDFYALPGIAGLVQRSGGEQEIMLGYSDSNKDGGFFTSNWELYCAEVALAEQFEQLKAEHGITLRLFHGRGGTVGRGGGPSFDAILAQPPGTVNGQIRLTEQGEVITSKYGNPEIGLRNLETLVAATLQATLLPQTKTASKPPARFLDAAAALSEASMAAYRKLVYETPEFTDYFYSATPISEIAELNIGSRPSSRKATRAIADLRAIPWGFSWGQCRVALPGWYGFGSGVQAFLDANPDGLKLLQRMAKQWPFFATLLSNIDMVLAKTDLRVAQRYAELVADSKTRQKVLKALQREWQLTTDMLTAITGNTERLADNPTLKRSIRARFPYIDPLNHLQIELLHRFREGQTDERTKRGIHLSINGIAAGLRNTG
>NC_014153.1|WP_013123439.1|1972390_1973371_-|patatin
MQTAPVSTPSTSAPRPRLGLALGGGAARGMAHLGVLRALADAGVRIDFIAGCSIGALVGAIAAAGRTDGLEATFKTFDWRKTLSFFDVVFPRSGLIDGAKVTELVREHLPATQIEALSIPFAAIATDLHSGAEVVLRSGDVIEAVRASIAVPGVFTPVRVDGRVLVDGGLSNPVPVSVVRAMGADQVIAVDLNHGVVDGRLKRRLRPKPRRSETSVEEPAGRWVADYRRVMADLKQRLQAPSAPAKDQFERWADREEPLPNVFEVLLASVNVMEMHITESRLRIEPPDLLIRPPLGDIRFLEFGRAEESIEIGYDAAMQALRGWNP
>NC_014153.1|WP_013123440.1|1973474_1973810_+|peptidase-M4
MKIRQSILIATLALASAAAGVSAFASNDGGNDARIIPNAKISLSQAVTAAEQHVGGTASKAEVEQHAGKAVYDVEVVKGAQVFDVKISPDQGTVIASTEDRNDHDDHDQQD
>NC_014153.1|WP_013123441.1|1973899_1974517_+|phosphatase-PAP2-family-protein
MLHFPVFWNALNLGLYTHWAAHGTASQASIDVALFFAEYAIYAAPLLLIWGWLRHPDALRPPLLQAAVAALVALGINQLIGLAVFEPRPFAIGLGPALLAHAPDSGFPSDHLTVIASVAASLLLTTTWRRAGLLLALLGLPVAWARVYLGVHWPLDMAGAALVGLMAALAVHLARHRLLEPAMPLLTGLYRKLFAPAIRQGWVLR
>NC_014153.1|WP_013123442.1|1974513_1975941_+|TolC-family-protein
MKQIVTPQPTAMTVPHLSRSVLLAALLLGGCASYHPEPLPTSADLAASANRLDVARSKIALPALTRYNFDTAKPLDATGLAILAVLNNPQLKAERARLGVARAQAFDAGLLPDPQLGLSQDFPGNSAGATTSAYNLGLSYDIAALITHHAAQSAAQHAATQVNLQVLWAEWQTVAQARLLYTQITGNAARLKLLEQERALFAQRLQRSQAALAQGNVTRLDVDAQLVPLQALTQTIQQIERQQLGLQSQLHALLGLQADVPLPLAAPSEQAAPTAAQVAAALEQLPRIRPDLMALQAGYAAQEQKVWQAVLGQFPAFNLGFTRARDTAGVNTVGFGVSISLPLFNRNQGVIATQRATRAQLLADYQARLDQADADVRQAQADIALLQQQRQTLQDALPALESADAAAQQALQQGGMSLLEFINQRTALLDQRLALQANAQQRAEQILALQLLTGLGPYRQTAALVTPSKSNAAPL
>NC_014153.1|WP_013123443.1|1975937_1977008_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MTLPTRARIALLAALSLPSLFLTLGSLPRAFAADSPISAQVQTAPLQRGELLHTLRAYAVVQVPASQTQAITFQHAMQVQTVDVHVGQAVRKGAVLATLRSDASTALAYSQAQTAVSFAQGELGRMTALKAQQLATQAQVDAARKALTDAQAQLHSLQQQGAGQAATRVLAPQDGIVLAVSAAPGDLLAAGSPLLQLGRSGSLQALAGVPPEDAPRLQPGQAVRLSSVFDPAQHWQGTIRSVGAAINPKTQRLDVQIALSAQAGLPPAGASVQADMVLGRWRGWVVPRDAVLQDERGAFVFQDDHGKALRIPVQIAIESGLQTGITGALNPAMPLVVAGNYELRPGMALRVMGAQR
>NC_014153.1|WP_013123444.1|1977004_1980289_+|efflux-RND-transporter-permease-subunit
MSGASVWLQRHRRSVLFLLALLAVGGVFAAFKLPVGLFPNVDFPRVVVSADAGDRPASQMMLQVTQPLEQAVRRVPGVVDVRSTTSRGTADISVSFDWGTPMALAAVQVNEAVTQMLPQLPPGTQVSSKRMDPTVDPVIAYSLTSNALTAAGPPQGGERPLGGQRASASVGAYTYTPTQLYDLAEFQLRPLLSSIGGVARVQIQGGAQEEYHVTLDPLKLQALGLALQDVSNAVSAANGVQAVGHLQDRYKLLLALADSRLHDAAQIGDIVLRAGPDGVIRLKDVAHISRSTVPQWVRITANGQDAVLLNIYQQPGGNTVQIARHVRELLAKTPLPPGVHLASWYDQSTLVVDSAASVRDAILIGVALAGLVLLLFLRSLKITLIAMITVPAVLAATVVLLYALGMSFNIMTLGGMAAAVGLVIDDAIVMSEHIVRRLSAPRAGLRPARPPWGSRKLGAARRFLESEARHRGEAQARHSGILHAAMEYLRPLAGSSASTVVIFLPLAFLSGVTGAFFKALSLTMAAALVISFFVAWLAVPLLADKLLSPKDIAREAQRENGRWLSAVQRGYARVLGASLRRPWLAALGLAPLLLAGWLGYGQVGSGFMPHMDEGGFILDYRTPPGTSLTETDRILAQVEQILRTTPEVQTWSRRTGAQLGGGVTEANEGDFFVRLKPPPRKSIDVVMEEVRQRIEAQVPGVKIELAQLMEDLIGDLTAVPQPVEIKIFDDNPQQLAQLAHRTAAAIGKIAGIVDVRSGIKPAGDALDIQIDPTRAALEGVDPQQVQQQLQTLIGGSVVTQIQQGPKMVGVRLWTPLALRQTTDDIARLPLRAPDGHVFTLGRIASLKVLTGQPEIHRENLKAMAAVTARISGRDLGSTIADVKKIIDAPGYFPPGVYAQLGGLYKQQQIAFQGLISVLGAAVLLVFLLLLFLYERFKVAISILAMPLLALPAVFIGLWAAGIELNISAMMGMTMIVGIVTEVAIFYFSEVQSLLHEHPEQGLDAALVAAGQNRMRPIAMTTLAAMLTLAPLALALGQGSAMQQPLAVAIIAGLAVQMPLVLLVMPVLFKLMRGRLDDAEADDNLPLSAVSPPTE
>NC_014153.1|WP_013123445.1|1980292_1980970_+|response-regulator-transcription-factor
MRILLVEDDHMLGAATREALRDATHAVDWVLDGASALSAAQGGEYELMLLDLGLPKRDGLSVLQALRQSGSNLPILILTARDALEDRVRGLDLGADDYLVKPFESAELLARIRAVARRQGGQAQPVLSNGVLELDPVSREVRFQGQTQRLTAREYALLHALLLRPGAILSRSELEDRIYGWNEEVESNAVEFLIHSLRKKLAPDVIKNVRGVGWLAPRGDTDKAP
>NC_014153.1|WP_013123446.1|1980966_1982307_+|HAMP-domain-containing-protein
MNPLAALRHWGAQSLLRRLWLWMTVSVVVVGLGTAALSYFFGYQEANELQDAQLRQIASLVHRWGHLPDSALNPAGADVDKDARIVVQRLGAPVGAHGLQLSKDLSDGMHVVQSGDHAWRVFVQQGDKGRIAVAQRTDVRTDAAIDSAQRTLFPLLALIPLLALLSAWVVQRALRPLRQMAQGVDARSEADLQPLPQTDVPQEILPFVHSINRLLQRLNASMEQQRRFVADAAHELRTPIAVLSMQVDNLKPLQLEPQARQRIGALQDGLRRARTVVEQLLSLARSQGEQTTLRQTLDPSGVMREVITDLLPLAESRGIDLGIDRAEKVEIDTDPAQLYTLLRNAVDNALRYTPEGGRVDLRVRAESERAVIEVQDSGPGIAPEQLQRVFDPFVRLPGAQSEGSGLGLSIIRQIAQRLGGEVALRNATEGGLILRYSQPLTSARSG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_5

2166179-2166348

Orphan

Consensus_repeat	Method
GGGCGTCACAGGTGACGCGTCAC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_014153_5

>merge|NC_014153|5|2166179-2166348|CRISPRCasFinder
GGGCGTCACAGGTGACGCGTCACGCGCGTCACTCCCTTTCTCTTTCTCTTCTTCTTTGGAGGGTGGGGTGTGGGGAGGGGGCGTCACGGGTGACGCGTCACAGCCGTCACATGTGACGTCACTGGTGACGTCACCGAGCGTCACTCCCGGCGTCACATGTGACGCTTGTG

>NC_014153|5|5|2166179-2166348|CRISPRCasFinder
GGGCGTCACAGGTGACGCGTCAC	GCGCGTCACTCCCTTTCTCTTTCTCTTCTTCTTTGGAGGGTGGGGTGTGGGGAGG
GGGCGTCACGGGTGACGCGTCAC	AGCCGTCACATGTGACGTCACTGGTGACGTCACCGAGCGTCACTCC
CGGCGTCACATGTGACGCTTGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013123611.1\|2170846_2171755_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176163
NC_014153.1\|WP_013123594.1\|2159715_2160543_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NC_014153.1\|WP_013123605.1\|2168171_2168600_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|273179
NC_014153.1\|WP_013123593.1\|2156083_2159500_-\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|225100
NC_014153.1\|WP_013123608.1\|2169199_2169472_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_141202375.1\|2166810_2166972_-\|AlpA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225848
NC_014153.1\|WP_155816273.1\|2163772_2164015_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013123597.1\|2163422_2163758_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|376623
NC_014153.1\|WP_013123596.1\|2162854_2163421_+\|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|381613
NC_014153.1\|WP_049774675.1\|2171799_2172171_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226140
NC_014153.1\|WP_013123607.1\|2168971_2169184_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013123592.1\|2152956_2156082_-\|type-III-restriction-protein-res-subunit	unknown	unknown	gnl\|CDD\|368155
NC_014153.1\|WP_013123600.1\|2164579_2165542_-\|chromosome-partitioning-protein-ParB	unknown	unknown	gnl\|CDD\|214678
NC_014153.1\|WP_013123599.1\|2164023_2164587_-\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013123595.1\|2160559_2162731_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NC_014153.1\|WP_013123603.1\|2167012_2167306_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374243
NC_014153.1\|WP_013123606.1\|2168596_2168803_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_155816272.1\|2152794_2152935_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013123610.1\|2169743_2170745_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NC_014153.1\|WP_013123604.1\|2167381_2168056_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013123611.1\|2170846_2171755_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176163	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 5. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.84572e-92
NC_014153.1\|WP_013123594.1\|2159715_2160543_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	2.04657e-46
NC_014153.1\|WP_013123605.1\|2168171_2168600_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|273179	TIGR00621, Single-stranded_DNA-binding_protein, single stranded DNA-binding protein (ssb). All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair].	1.03386e-48
NC_014153.1\|WP_013123593.1\|2156083_2159500_-\|site-specific-DNA-methyltransferase	gnl\|CDD\|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	7.44072e-18
NC_014153.1\|WP_141202375.1\|2166810_2166972_-\|AlpA-family-transcriptional-regulator	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	9.42456e-05
NC_014153.1\|WP_013123604.1\|2167381_2168056_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	4.56423e-22
NC_014153.1\|WP_013123597.1\|2163422_2163758_-\|chorismate-mutase	gnl\|CDD\|376623	pfam01817, CM_2, Chorismate mutase type II. Chorismate mutase EC:5.4.99.5 catalyzes the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine.	1.42625e-19
NC_014153.1\|WP_013123596.1\|2162854_2163421_+\|lytic-transglycosylase-domain-containing-protein	gnl\|CDD\|381613	cd16892, LT_VirB1-like, VirB1-like subfamily. This subfamily includes VirB1 protein, one of twelve proteins making up type IV secretion systems (T4SS). T4SS are macromolecular assemblies generally composed of VirB1-11 and VirD4 proteins, and are used by bacteria to transport material across their membranes. VirB1 acts as a lytic transglycosylase (LT), and is important with respect to piercing the peptidoglycan layer in the periplasm. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).	2.01223e-59
NC_014153.1\|WP_013123592.1\|2152956_2156082_-\|type-III-restriction-protein-res-subunit	gnl\|CDD\|368155	pfam04851, ResIII, Type III restriction enzyme, res subunit.	6.20476e-10
NC_014153.1\|WP_013123600.1\|2164579_2165542_-\|chromosome-partitioning-protein-ParB	gnl\|CDD\|214678	smart00470, ParB, ParB-like nuclease domain. Plasmid RK2 ParB preferentially cleaves single-stranded DNA. ParB also nicks supercoiled plasmid DNA preferably at sites with potential single-stranded character, like AT-rich regions and sequences that can form cruciform structures. ParB also exhibits 5-->3 exonuclease activity.	7.43546e-14
NC_014153.1\|WP_013123595.1\|2160559_2162731_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NC_014153.1\|WP_013123603.1\|2167012_2167306_-\|hypothetical-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	7.65113e-13
NC_014153.1\|WP_049774675.1\|2171799_2172171_+\|hypothetical-protein	gnl\|CDD\|226140	COG3613, COG3613, Nucleoside 2-deoxyribosyltransferase [Nucleotide transport and metabolism].	7.4839e-16
NC_014153.1\|WP_013123610.1\|2169743_2170745_-\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	9.45562e-178

>NC_014153.1|WP_013123600.1|2164579_2165542_-|chromosome-partitioning-protein-ParB
MMQATAMTSTTALPLDFGTPGADPQQLRAVPLDAVQTESDFPVRRLDADTLDDLARSLQIVGQLQPIGVRAAGKNWSLIYGERRVRAARLLGWRTLLARVFSPIGAAPVVLRATENMHRQEFSLEDASDTVLRLVSAGMTPPSIAKALARREAWVTSMLSFARNPLARELASLGRLQSISAWESFAALDQAEQGAVLDSSDTITVARCDEARQASRQKEARRQRHLAPATSEVSPSAAHAECEAAQACVAPSAQACASTEQDIDWQEENPPSDNAITIALRPGQKQALQRIMADENRDLDDILQEAVDVYLAHRQGAGHE
>NC_014153.1|WP_013123599.1|2164023_2164587_-|hypothetical-protein
MNETQMTATQSAQALFTSLLDEQVHLFAGVSTLSMDDVRQSLYLFCLEHAAGLDAFNPLLGTPKNYIMGRMWGLIERWRPMSSLDDMLSDDHDPPIRQRLPDAMQAPGVEAALIARAQRQTEDQIRDDLELSSRKSLHGLPTAVALVTHCDRPLSEVARRCGKNRWRLRQAVRQQRSGLAQGGGLAG
>NC_014153.1|WP_155816273.1|2163772_2164015_-|hypothetical-protein
MKTVGHRNPHSITLHARAGALEEFGRFNDAFHSLARTRILLPKGVFRLSHEEADQQMTEGIARGMALLAADRDQGASGAT
>NC_014153.1|WP_013123597.1|2163422_2163758_-|chorismate-mutase
MQRMLQTLRSEIDAIDEQLIELLAGRFAVTRQVGQLKAHHALPAVDTERESAQQFRYEQLARANGLDPALVMGLFRDIIAAVVRQHGEAITPERPGSSQPPRSRKDHGNER
>NC_014153.1|WP_013123596.1|2162854_2163421_+|lytic-transglycosylase-domain-containing-protein
MNAIALMQQCAPQIAPVTLAAVVQQESGGNALALHDNTSGKSYAPTTVAEAARLARELIAQGHSVDIGLAQINSGNLPRLGLGVDQVLNLCTNLRAAQSVLMEGWARSGNLRATLSAYNTGRLRSPVGMAYGEKVFGKAGVVVPAIPGGQIASWATVGAALPPVRPVVTWTPQASPLVPKGDGLAAKW
>NC_014153.1|WP_013123595.1|2160559_2162731_-|DNA-topoisomerase-III
MRLIIAEKPSVAQAIADVIGGVRRGDGYIDCPQAKTRVTWCFGHLLEQARPEDYVNGGKVLASHLPVIPTAWKLAPRDGGAGKQIKAIRDLLKDATEVVNAGDADREGQLLVDEVLLFLNWKGKTTRLWLSSLDDESVRRALVTVKSNDALRPLYESALARQRADWLMGMNASIALSRNLQACGVQGAWSVGRVQTPTLALLVDRQRDIQNFKPRDHYQVQATLDGDIRALWQIPEDLQTDDGLLLDKSAAETCAQAVQGQRATVAAFTRKAGERQAPMPYALSTLQKTASSRLGLSAKDTLAAAQELYEAKLATYPRSDCPWLPVEMHAAAAQIIRALGAAEMAGIDPERRHPAWNTAKVEAHHGIIPTGRGLAEVSGLSENAKKIYGLLRESYLRLFMPPETFETREALFTFPGAERFKASARIVQESGWTQLGQADNSAEDDETGQVARLPILTEGQQLACESAQVLAKRTSPPKPYTDGTLIAAMTGVHKLVTDPKLKARLKETSGLGTEATRASMIEVLIAREYAERKKKEIHPTERGVQLIDMLRKVAPDLADPGTTALQEDALAAIASARSTFDEFMTAQIDAVRESTQKLLGGQLGATPAILHACPACGGGRCAQRTSKAGATYHRCLDCDAAFGDDGGKPGKRFEDKHQSEGAAAKAPASGPKCLSCKKPTFKNETKTGKPYYRCGGCKGAWWPDRKDEGKLGTKWEERAGARA
>NC_014153.1|WP_013123594.1|2159715_2160543_-|Fic-family-protein
MSQSLAALLKLIDTRKAQLDALRPLPPATVASLHDKLALEWTYNSNAIEGNTLTLRETQVVLEGITVGGKSLREHLEAINHQEAIGAVESLIQSGKQMTEWDVRGIHQIVLKGIAPERAGRYRTENVAIVGASHTPPAAVQVPERMTELIRWLDSPPSHGLHPVARAAEFHTRFVEIHPFVDGNGRTGRLLMNAVLMQEGYPPAVIRAENRPAYYDALDRACVTKDYGDITRLVAQETIRSLDSYLEVIEGRLPGREPEQTQRRVKRPGRTGVER
>NC_014153.1|WP_013123593.1|2156083_2159500_-|site-specific-DNA-methyltransferase
MTQEPSTFELFQNFLREMFQFDNNELDFGLFKVLRLKRAFIEQFIDGDGEQDLRRIVSRELAAIRSADDADEKQWLANRCELLGIKTKKAWENALANLRDKALNEALRQAVQNAEEDDKLTVTLERLDRWLQAQQHSTSHLEAQLYNYLLNFFELYYQNGDFGYNSRAASAFKVPYEADYDGADTLFHYKHKDCYYIKTANSFPEVRLEVQGKKLVFRIQAGGDDEATAQNNNKDADIKLYRLVGIAEQDGECIVSFQLAKSGTPKTELYPQLLHALGITADARAYLWQKDKDGEKAIFKELGKDHDKTEGGQVKGINQLRLVADSYRETLAKQDAFKNLGRNAEDRQEALKNDPTTQTLLQIDKALNRFYVGQDADYFIHKDLHGFLSREKDRFIKNVIFSDLDALLDPRADAATRMLARAFNAVATRIIEFLDATETFQKNLFTLKKKVIDTHWLISLGKIPEAYWPRLLENPRLVAYWQSEVKQTVKSLDDLIARPTLVVDTSLFTTDAGQALIDDILSDPAFDHLDEQTDGMLIHSENWQALNLLQEKFRERIQCIYIDPPYNTGGDGFLYKDSFRHSSWAAMMADRLALAKPLLGTHGVLFASIDDKERLSLERLLADTFGAENRVEELIWAQNTTKNQSPTYSTNHEYVEVFARSLTNVTQAEAMFREPKPGYAEMMELVERMNPDYPPLAEVEQAIKTLFDQHKEELKAEQEELGIEYEKNLDPWKGLYNYTHAEYRTGEGRLVGELEARQLEATLWIWREDNPSAPAGKQSPTTKDPNDPNYRFYKPMHANGKRCEPPKRGWGWPEKPIAEEPNRPSFSSLESDSRIVWGKDEKKKPQIKKFLHEVDTQVSKSVVLDYTDGEKELTNLTGSPNSFPNPKPTTLIGRFIEQTTEPKDWVMDFFAGSGTCGHAVLALEQPRRFVLTEMGGYWDTVTKPRIARLMFSPHWKNGEPGAAHRRRHIVKVQRFEQYEDVVNALDTVWDEAALPEGVPLRYLFRPDQNRVRLSLNLARPFGNTLRAGKQGEPRTVDLLETWALLRGYWIRSRKVVEHAGKRYAALESECGCLVLLRDIAEGEDDSAAINAIAVGYVNEDGSRRIQRLELNHWADLRKIALPCTLLTASDFDRGATWG
>NC_014153.1|WP_013123592.1|2152956_2156082_-|type-III-restriction-protein-res-subunit
MELRLYHHLKRELLGGLAPASERHDPAYQKAVEAYAAEAETGIRKWSREAIADWLNHYNRLMSRPVRLRYYQILALYFTEQVLREERAAGVGLNGVQRNKLAYWMATGSGKTLLMHLNILQYIAHIGGMQAFDELQIILTTPGVNLIDQHRRELTPLIDALNRQCANRIKLTVESTGSLLNHERGYFNLPPSSRVFRLVLVDEGHIGLAGGGKEAGAFKQLRHDLADFPNAFLFEYSATYHGINDKYVDEYGDQIVYDYNYYRFFKDGYGKDYSLQKVAADDIDKGQEAWANFQTAFLTLADKLAVYDELRLKDDGLGFVSSFADKPLIAFMGNTVEDKKKEGKGQDDEVSDIRKLLAYLAKLTPEQRRQLAPVFNGDAAGNLVGPLTLTRCAAVTDEIYLSWGDGAYWGIVNVGNGDKFFNDSENHPELLDAHKKPLVQLRKAAIVERRFQFSDIDLPGSTINVLVGSRKFAEGWNCYRVSVIGLINLGSSKGNKIIQIFGRGVRLRGLKGDGKRRAIEHLADYDALVEEDTAKNRMRRLETLNVFSLKASYLEIFLKGLEQELPRWIVERRVAVEAQTLKLGKAAESFEQYSKKLPIFKVGRDDSEPRLLATQNFKDGKPAWHWAYFHTDGEESGELARLNLRMDYRPDAADEAVNLAEDLRQAVKQGKAGFLPLADFQLRLESLQKSRKMQLLVQKDRVAHPLTLDDLLGLVGEVLYSRAWAGLGFALREQLLAQTLSDAIAKLHHKLIYDLNKRRYRLDEPLRQSADGDPGDFISHYDLRIEFEKEADKAKFEAAYPSPDLPAQLPLTLQEPRHIYAPLLKNGEDKEVKRGFTFKTLSISPDALNPGERKFVQDLHVYLANPVNLGRLRKFDFYLMRNVESLRSVGVYLDSETRAYYPDFVLWAVSDQKTHVMLVDPKGQSGIQNWQSLHDPYNAKVALATSPDLVELAKRLASISGKAAKVDSFILLRKTSPLGRANGTHYDLAQVKDMQRRHVLHLDWAPADEHGQRVDEEGNPAPAPPDQRCYVERMLACAGLL
>NC_014153.1|WP_155816272.1|2152794_2152935_+|hypothetical-protein
MPALTAALLPMPTTVWASLPPPRVCVAESDTPLRAAFSPGAVNYGF
>NC_014153.1|WP_141202375.1|2166810_2166972_-|AlpA-family-transcriptional-regulator
MLSMGRSTFWRNVSAGVLPQPVRIGGLTRWRIADLVRVVDLGAQTMAEQGRAA
>NC_014153.1|WP_013123603.1|2167012_2167306_-|hypothetical-protein
MRANTRLSEATSAHGGLSACARMIGVRPPTLHQWIKGLRPVPPRRCHAIEYALAVRRWDLRPNDWHLIWPELVRAPGAPAVTESAPGAGPPQEDSRE
>NC_014153.1|WP_013123604.1|2167381_2168056_+|helix-turn-helix-transcriptional-regulator
MLTGKELGAAIEAARLKKGVSKVTLARAMEIKPPSVQDWIHHGRVAKSRLGALFQYFSDVVGPEHWGVREEWGYNPSLRIVDGMVTLPQYDLKAAAGPGRYLEAQLRVGAVQVCQDIVARILRNSGVALTSLALVTVAGDSMEPTINDGDIVVIDRSVETIDRDGVYLFTFGDETFIKRIQRMPKSLSVNSDNGLYKGWEISSEETSSLHVHGRVIWAWLGKPI
>NC_014153.1|WP_013123605.1|2168171_2168600_+|single-stranded-DNA-binding-protein
MPSLNKVQLIGHLGRDPEVRYTADGVAVATLALATSRAWKDKGGERREDTEWSRVVLFGRLAEIAADFLSKGTQAYIEGQLRTRKWADKDGTERYTTEVVADELLLLTRREKDKPADAAAAAATATGGLEWPVLGDPSGSAS
>NC_014153.1|WP_013123606.1|2168596_2168803_+|hypothetical-protein
MMFKRAPVNDALVGDRDGFAGRDPNPALWPREAYRRGYAQGLLTRAERIAQGALPLPVARRSVAEVRQ
>NC_014153.1|WP_013123607.1|2168971_2169184_+|hypothetical-protein
MQYVGMAFIVALLALVWFADLFMRAPLGIKLLFLSPLLWATAKLLWAVYKRLAWEIKRRRMAARNQRAAD
>NC_014153.1|WP_013123608.1|2169199_2169472_+|hypothetical-protein
MLKEWLEPPQRLIALARIGLHPSPADIETAIRCLDKAQDAMRNNGQSAVALHPARAALVSLRWGHLPHRDACISAVANLGAVMALGEEVE
>NC_014153.1|WP_013123610.1|2169743_2170745_-|aldo/keto-reductase
MNQRQLGNSGLTVSALGLGCMGMSFAYGGALDDDSIRAVHRAFELGVTFFDTAEVYGPFTNEELLGKAIKGLPRDRIQIATKFGFKILPHGNGLERMVGVDSRPSHVREVVEQSLKRLDIDAIDLLYQHRVDPAIPIEDIVGAMADLVAAGKVRHLGLCEVSTATLRAAHAVHPISAVQSEYSLWSREPERGVLGVCRQLGIGFVPYSPLGRGFLTGKLTSADQLAASDFRKSLPRFQAEALARNLRVFELFGEVVRAKGCTPAQLALAWLLAQGDFIVPIPGARTLEHIEDNAGAAALQLSASEIRAVESALDPQAISGARYNEGDLALVEG
>NC_014153.1|WP_013123611.1|2170846_2171755_+|LysR-family-transcriptional-regulator
MHADFNELACFAAIARLRSFRKAADERNVTASSLSHTMRSLEERLGVRLLNRTTRSVVLTDAGSQLLSRIEPMLAGISEALDQTHSLGSSLKGTLRLNVPRPAGRVLLAPIMDGFLRDHPETVIELITDDGIIDIVQTGFDAGVRFGESVALDMVAVPIGPAQRLVLVASPAYVSKTGPIRHPEDLKQRACIGRRFPSGLHYAWEFEKDGEKIAVRVVGPLVLDDDDMMVKAAAGGIGYAYVHESTAKSLLDSGQLARSLDDWCPFIPSFHLYYPSRRHVSTVLRAFIDWCNAYYAGSGATR
>NC_014153.1|WP_049774675.1|2171799_2172171_+|hypothetical-protein
MRLLRDCDGVLANLSPFCGVEPYSGSVFEAAFALAIGKPVAAWIGDHWNTRERSAVLRRVWRDADGRVRDKNDGGLVEDFGLSVNLMLACSFAVMPTPWHAIERLAELLGVELMAHGVPEPHD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_6

2220675-2220769

Orphan

Consensus_repeat	Method
AGCAATCCTTGCGCTCCGTCCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_6

>merge|NC_014153|6|2220675-2220769|CRISPRCasFinder
AGCAATCCCTGCGCACCAAGCAATCCTTGCGCTCCGTCCAAGAAAATGGACAAAAAAATGGAAAAGAAGAGCAGCAATCCTTGCGCTCCTTCCAA

>NC_014153|6|6|2220675-2220769|CRISPRCasFinder
AGCAATCCCTGCGCACCAAGCAA	TCCTTGCGCTCCGTCCAAGAAAATGGACAAAAAAATGGAAAAGAAGAGC
AGCAATCCTTGCGCTCCTTCCAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013123657.1\|2219842_2220448_+\|YeeE/YedE-family-protein	unknown	unknown	gnl\|CDD\|377230
NC_014153.1\|WP_013123649.1\|2212652_2213042_+\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|225418
NC_014153.1\|WP_013123661.1\|2223573_2225232_+\|TIGR03016-family-PEP-CTERM-system-associated-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274391
NC_014153.1\|WP_013123666.1\|2237598_2242551_+\|non-ribosomal-peptide-synthetase	unknown	unknown	gnl\|CDD\|237108
NC_014153.1\|WP_013123652.1\|2215187_2216192_-\|PA2778-family-cysteine-peptidase	unknown	unknown	gnl\|CDD\|239109
NC_014153.1\|WP_013123650.1\|2213052_2214390_+\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|223523
NC_014153.1\|WP_013123667.1\|2242601_2243645_+\|cupin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372651
NC_014153.1\|WP_013123662.1\|2225241_2227389_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|132060
NC_014153.1\|WP_013123664.1\|2229058_2230009_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274392
NC_014153.1\|WP_041608444.1\|2230136_2237591_+\|type-I-polyketide-synthase	unknown	unknown	gnl\|CDD\|225858
NC_014153.1\|WP_013123648.1\|2211407_2212643_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013123658.1\|2220848_2221568_+\|hypothetical-protein	unknown	unknown	unknown
NC_014153.1\|WP_013123659.1\|2221633_2222620_+\|sulfurtransferase	unknown	unknown	gnl\|CDD\|225450
NC_014153.1\|WP_013123660.1\|2222914_2223532_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|132072
NC_014153.1\|WP_013123655.1\|2217621_2218911_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223523
NC_014153.1\|WP_013123663.1\|2227441_2229049_+\|polysaccharide-chain-length-determinant-protein,-PEP-CTERM-locus-subfamily	unknown	unknown	gnl\|CDD\|274386
NC_014153.1\|WP_013123656.1\|2219336_2219846_+\|YeeE/YedE-family-protein	unknown	unknown	gnl\|CDD\|377230
NC_014153.1\|WP_013123654.1\|2216675_2217482_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_014153.1\|WP_013123651.1\|2214386_2215145_+\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|225418
NC_014153.1\|WP_013123653.1\|2216202_2216580_-\|PA2779-family-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013123657.1\|2219842_2220448_+\|YeeE/YedE-family-protein	gnl\|CDD\|377230	pfam04143, Sulf_transp, Sulphur transport. This is an integral membrane protein. It is predicted to have a function in the transport of sulphur-containing molecules. It contains several conserved glycines and an invariant cysteine that is probably an important functional residue.	5.9192e-10
NC_014153.1\|WP_013123649.1\|2212652_2213042_+\|c-type-cytochrome	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	2.74805e-13
NC_014153.1\|WP_013123661.1\|2223573_2225232_+\|TIGR03016-family-PEP-CTERM-system-associated-outer-membrane-protein	gnl\|CDD\|274391	TIGR03016, hypothetical_protein, uncharacterized protein, PEP-CTERM system associated. Members of this protein family are found predominantly in exopolysaccharide biosynthesis operons marked by the presence of the EpsH-family putative exosortase and presence in the genome of the PEP-CTERM protein sorting signal. Members of this family may be distantly related to the EpsL family modeled in TIGR03014.	3.16835e-32
NC_014153.1\|WP_013123666.1\|2237598_2242551_+\|non-ribosomal-peptide-synthetase	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_014153.1\|WP_013123650.1\|2213052_2214390_+\|pyridine-nucleotide-disulfide-oxidoreductase	gnl\|CDD\|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	2.92464e-19
NC_014153.1\|WP_013123667.1\|2242601_2243645_+\|cupin-like-domain-containing-protein	gnl\|CDD\|372651	pfam13621, Cupin_8, Cupin-like domain. This cupin like domain shares similarity to the JmjC domain.	3.39492e-39
NC_014153.1\|WP_013123662.1\|2225241_2227389_+\|AAA-family-ATPase	gnl\|CDD\|132060	TIGR03015, pepcterm_ATPase, putative secretion ATPase, PEP-CTERM locus subfamily. Members of this protein are marked as probable ATPases by the nucleotide binding P-loop motif GXXGXGKTT, a motif DEAQ similar to the DEAD/H box of helicases, and extensive homology to ATPases of MSHA-type pilus systems and to GspA proteins associated with type II protein secretion systems. [Protein fate, Protein and peptide secretion and trafficking].	2.61131e-129
NC_014153.1\|WP_013123664.1\|2229058_2230009_+\|AAA-family-ATPase	gnl\|CDD\|274392	TIGR03018, pepcterm_TyrKin, exopolysaccharide/PEP-CTERM locus tyrosine autokinase. Members of this protein family are related to a known protein-tyrosine autokinase and to numerous homologs from exopolysaccharide biosynthesis region proteins, many of which are designated as chain length determinants. Most members of this family contain a short region, immediately C-terminal to the region modeled here, with an abundance of Tyr residues. These C-terminal tyrosine residues are likely to be autophosphorylation sites. Some members of this family are fusion proteins.	1.72389e-83
NC_014153.1\|WP_041608444.1\|2230136_2237591_+\|type-I-polyketide-synthase	gnl\|CDD\|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_014153.1\|WP_013123659.1\|2221633_2222620_+\|sulfurtransferase	gnl\|CDD\|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	2.58554e-46
NC_014153.1\|WP_013123660.1\|2222914_2223532_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|132072	TIGR03027, pepcterm_export, putative polysaccharide export protein, PEP-CTERM sytem-associated. This protein family belongs to the larger set of polysaccharide biosynthesis/export proteins described by pfam02563. Members of this family are variable in either containing of lacking a 78-residue insert, but appear to fall within a single clade, nevertheless, where the regions in which the gene is found encode components of the PEP-CTERM/EpsH proposed exosortase protein sorting system. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	5.24683e-84
NC_014153.1\|WP_013123655.1\|2217621_2218911_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	2.86746e-29
NC_014153.1\|WP_013123663.1\|2227441_2229049_+\|polysaccharide-chain-length-determinant-protein,-PEP-CTERM-locus-subfamily	gnl\|CDD\|274386	TIGR03007, pepcterm_ChnLen, polysaccharide chain length determinant protein, PEP-CTERM locus subfamily. Members of this protein family belong to the family of polysaccharide chain length determinant proteins (pfam02706). All are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria, and are found near the epsH homolog that is the putative exosortase gene. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	2.38945e-135
NC_014153.1\|WP_013123656.1\|2219336_2219846_+\|YeeE/YedE-family-protein	gnl\|CDD\|377230	pfam04143, Sulf_transp, Sulphur transport. This is an integral membrane protein. It is predicted to have a function in the transport of sulphur-containing molecules. It contains several conserved glycines and an invariant cysteine that is probably an important functional residue.	2.17928e-12
NC_014153.1\|WP_013123654.1\|2216675_2217482_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.26642e-25
NC_014153.1\|WP_013123651.1\|2214386_2215145_+\|c-type-cytochrome	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	3.23656e-13
NC_014153.1\|WP_013123652.1\|2215187_2216192_-\|PA2778-family-cysteine-peptidase	gnl\|CDD\|239109	cd02549, Peptidase_C39A, A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic). The cleavage is mediated by the transporter as part of the secretion process. Bacteriocins are antibiotic proteins secreted by some species of bacteria that inhibit the growth of other bacterial species. The bacteriocin is synthesized as a precursor with an N-terminal leader peptide, and processing involves removal of the leader peptide by cleavage at a Gly-Gly bond, followed by translocation of the mature bacteriocin across the cytoplasmic membrane. Most endopeptidases of family C39 are N-terminal domains in larger proteins (ABC transporters) that serve both functions. The proposed protease active site is conserved in this sub-family of proteins with a single peptidase domain, which are lacking the nucleotide-binding transporter signature or have different domain architectures.	1.53502e-20

>NC_014153.1|WP_013123657.1|2219842_2220448_+|YeeE/YedE-family-protein
MSFPLGYTGPVSGIILGLIFGYILENAGFGSGCKLTAQLRFKDWAVFKVMFTAILVSAGGLYLLQGLGVIAVDNMFVPSVFLWGSSLGGVLIGVGMAVGGYCPGTSIVALFSGKLDGLIFLLGIGIGTLGFNSVFSSIEGWAWKQVGPDGLTLPQLLHLPAWAVWGLLFAVLVVVGYLTRTNASARKTSNKSSGSFAPQNS
>NC_014153.1|WP_013123656.1|2219336_2219846_+|YeeE/YedE-family-protein
MRNTPRPLWNPYVAGVLLGLGLLATFLVTGNGYGVTGATTLATAAVAGKIDPNTVAAHTYLHNLFEVGLDRWVVWEVVGLAIGGLIGSVLAGRFKLQIDGPTQAGRSLRLVLAVIGGIAAGFGARLALGCTSGMGLSGSATLAAAGFLFLIGFFIAGAVFGQLTKGLWK
>NC_014153.1|WP_013123655.1|2217621_2218911_-|NAD(P)/FAD-dependent-oxidoreductase
MAHIVVLGAGIGGMPAAYEAREALGKAHKITVINAVDYFQFVPSNPWVAVGWRSRDEVIFAIKPYLERKGIDFIAKSVTKIEPESNTLTLQDGAKVNYDYLIITTGPKLSFEEVPGSGPHGGYTNSICSIDHAEKCYTDYEKLVANPGPVIVGAMPGASCFGPAYEYTMVLDTALRKKKIRNKVPITYVTSEPYIGHLGLDGVGDSKGIMESAFRSHDIRWITNAKTTKVEDGKMFVDELDMQGNLVKQHELPFKHSMMLPAFKGVDAVAAVEGLCNPRGFVIVDQHQRSPKYKNIYSAGVCIAIPPTGPTPVACGVPKTGYMIESMVTAIVHNLEEELAGKQPSHRGTWQAICLADFGNTGAAFVAIPQIPPRNVNWFGEGKWVHLAKIAFEKYFIRKMKKGNSEPIYEKYMMKLIGMERLLHPERKD
>NC_014153.1|WP_013123654.1|2216675_2217482_-|sulfite-exporter-TauE/SafE-family-protein
MWLSIAIFLLAGASAGFLGGLLGIGGGLLLVAALSFALPALGIPADEVIHVAVATSMASIVLTFISSATAHIRRGGVLWPSWRWLAPGMVIGGFIGAHLAQMLSGPVLRYVIAGFCAVMAVQMAAGKRKKTVPGQEHIPRSPWLLPAGVGIGAVSSVVGIGGGSMTVPLLVALGVQPVKAVATSTVCGLAIALSSALSYMISVHAPAHPLPPGAFGYVFLPAAAATAVASMVLAPYGVRVAHRISGDALKRVFSIFLIFIGALIAFGG
>NC_014153.1|WP_013123653.1|2216202_2216580_-|PA2779-family-protein
MFPSRISRQFLVAALGVSLMAAAPAARAELIGTQQLTQPQPGQDAATLAADRSTLDHFMARADVQAKLEQMGLSQEVTQQRLAALSNAEVAQLAGRINSMPAAGALGFQEMVIILLVAILVVLAL
>NC_014153.1|WP_013123652.1|2215187_2216192_-|PA2778-family-cysteine-peptidase
MTGRRLRVASQLTLALSLLLGGCAALPPGVFSTAPLQFQQGRLVDEPAGLPASANVAGVPFFSDDSHYCGPASLASVLVFSGVRTTPKQLIPQVFTPGLEGSLQFDLLGASRRAGRIPVVLPPKLGAVFEQVAAGFPVVVLQKVGLGVRDWHYAVLVAYDLPGDRVTLRSSTARDLQLSIEQFDRSWAAGGRWAFIAVKPGQFPPGIDELTYLRAVAPLEGVAPEAARTAYEAALKRWPKAWIAMMGLGNLAYARKDYPQAAIHFAEAARANPSDGDPMNNLAQALLAAGDWKAAQGAIEVALRLGQPHPEAYRSTAAEIAKARAAALDPTQAP
>NC_014153.1|WP_013123651.1|2214386_2215145_+|c-type-cytochrome
MITAAFPTAWRTLALAAALFVSSLAQASEHNKPAPKPWSPVTLQTALGDLPKGNAAAGKAVHDSMMCASCHGAAGNAATMNWPSVAGQRYDYTAKMLLDYRSGLRFEDERAGLMTSIARLMTPQQIADVSAYYASLPKPVAPQAQAALAAPLTAAEHKRVEQLVRKGDANRLITACASCHGLHGEGKGTTPAIAGQTTDYFIRTMRLYHNGERQNDVYKGMSQFSQRLSDADTLLIARYYASQGQSQTAKAD
>NC_014153.1|WP_013123650.1|2213052_2214390_+|pyridine-nucleotide-disulfide-oxidoreductase
MNSRRQFLLASATALGAVAFPAIARAGQASARIVIVGGGVGGATAAKYLKLADPSLQITVIEKNPVYIRPYGSSEVLNAHVTMQDLRVSYDVLRHKHGVAFVFDAAKSLDPVNKTVTTASGKVLGYDKLIVSPGIKLRYDSLPGYSEQLADSLVPSGWIAGAQTALLAKQLQSMRDGGTFVLAAPPNPYRCPPGPYERAALMTEWFSKHNPRAKVIIADPKDSFVTDETALLGWNRLYGFQPPAEYRTKLAAELQPSTQPCALEWIQAKSGGTPQRLDAKTMTLHTAGGAIKADVINVIPAMVAGQIAFDFGLTNTSGFCPVHRVTFESTLHNDVYVIGDSSVADAMPKSGFSANTQAKWVARVITDGLAGRDPGTPVWENTCYALAGKDYGLFVADVFKIKEDGKIGRVNKARYLPLDATPAQIRLSAVYQQAWIQAFTQDIFA
>NC_014153.1|WP_013123649.1|2212652_2213042_+|c-type-cytochrome
MRLHHLTLVLIGLVFAIGLLGANAPAFAAPAAPAAVGTPVAATLPPGPKAPPTGAAMAQTCAGCHGTDGRLHAAAFMPLAGMPKAQLAQAMRDFRDGKRPSTLMGHVAQGFSNGEIDAMASYFAAVKPE
>NC_014153.1|WP_013123648.1|2211407_2212643_+|hypothetical-protein
MNSEMLYALRDVAGVPSHPIVFLVLGVLTFALHIAAVQVMLGGTALVLANAFSRNPMRRRLAAAMTTTAKIAVSVAVVLGVAPLLFVQVTYDPFWYTSNVLSAWWVVGFIVLLIAGYMALYFFYSRNHHLDDPQHDTRSGWSLVAALALFLVVGFIMHVLTQQMLSPEKWMSWYAPGGVIEPRGRTLHDYNLWRFGFFIALAAPVTGAWLFAYRRYLSAGQLAEANYLQWVGALASKMLNIGGVIALVFLGGWMATLPANIAGFATSPIVLLSVALLLLTVALPTVLGQRTLHTSLGYAPFALGAVALIAVAALREVLRWTVLKGIHGYDVFTYPVHLDWYSNVLFFSTFALIGGSTLAYFLTIAWKVGQTPKGQIYTPSAAIDRIGTVSMWLVGLWIVQFFVVGFVVWAQ
>NC_014153.1|WP_013123658.1|2220848_2221568_+|hypothetical-protein
MLQSSSLLSGRAPKGRRFTADLLRALPPQERSDLYAYGLKALEATQSLLQQGKTVISEIIGNAAYVEWEHYPQRDAKSRTGALFYYHAHAANQRMPAEHGHFHVFAPNDRAECPSDQRYTHIAGLSVDARGMPLRVFTTNQWVTAECWEDADRVCTLARQTTLKDAKPHRVGQWLDAVFAFFRPQIDLIAHMRDARVKALLARGRTQLLEDRRTHILSQCRIDFSTQIFALEELGADAP
>NC_014153.1|WP_013123659.1|2221633_2222620_+|sulfurtransferase
MKLKHLIGMSIIAVAAAQTAGAATLPGPLVTPQWLNANKDAVTIIDIRDEPKTFTEAPKFEVDPKTKVKTLVKTGGHIEGAIPVDFGKIRQERTVDGVKIKAQLPTAEYFTKVMDDSGLNKTDKPIVIVPTGESVDSMDMATRLYFQLRYFGEPRDKLAILNGGVNAWIQAGYPVSTDKVTPTKGDWAAGAEDKAILASMQQVKEGLQGGKDQFIDARPTAQFLGIVKKPINKTAGHLPGARSFPTDAIVKPVGAAHEFMSADDYKKIYAEFNIQPDAQTITYCNTGHLASGAWFVSHEILGNKNSKLYTGSMIEWTNLGNPTVGLPQ
>NC_014153.1|WP_013123660.1|2222914_2223532_+|sugar-ABC-transporter-substrate-binding-protein
MLIRNSRFSLWRMAAATMAALLLGACAANNYPPAPEKITQGAYHYKVGAGDTLNINVWRNPDLSMSIQVRPDGKISTPLAPDVQAAGKTPGEIGQEIEARLSKYVRDPVVSVVVTGFHGPYSQQIRIVGQAVRPIAIPYRENMTLLDVMIAAGGLTEFADGNAAVLERHGKTYSIKLGNLLKRGEMSANVPVEPGDVIIIPQSMF
>NC_014153.1|WP_013123661.1|2223573_2225232_+|TIGR03016-family-PEP-CTERM-system-associated-outer-membrane-protein
MQTSSRKVLFALTPLAFCLLQAGSACAQAIPGLNLAVPGGGALPQQLEGGETQGGLLTPLGTASAPLPARGNFVQPSVGMSVVQTSNVYFGSNNPARSDTIVSVTPGIAFQTLGPDLRTFGNFALNAQYYARSSYSNTVLPSGTLGLNARLVDQWLYFDAGINSQQNALLTIPAQSTGTATYTTTQYSLSPYIDHRFNDDLRLRARSENVWTRISGNQTGAALSNGRYGKQSIRLDRRPTPLGWGLDAKQEETVYTDSGSLAVRDEIARARVLYAFTPHFEGGLIGGYEHYSTGYASLGHSIYGVQLNWRPNVFTRFDGVVERRFFGTGWDISASQQIQRLSLRLNWNRAPSSYLASLQTIPSGVSLSTLLGGMLASQYPDPAARAQAVQNLLAVTGLPATLPNAVNYYTQSATLQDTLTLTGVLLAQRNSYTVSVFHTKTQDLILPGSPPLNNLLLASADYVQNGIGLSYGRRLTPVMSLNVGLLRALSTGFGPNEGVSTRQTTFIVQLSRRLTPQTILVLGARRQLLDTANSGILSANESAVYAGVTHQF
>NC_014153.1|WP_013123662.1|2225241_2227389_+|AAA-family-ATPase
MYAAHFGLSAPPFQLNPDPSFLFESKGHNYAHQYLRFGAMQGEGFIIVTGEIGAGKTTLVRALLNELDPTKVAAAQIVSTQLEAEDLLRAVANAFGVPSKNASKAELLAALEAHFTTLMLQNRRALLVIDEAQNLNAAAIEELRMLSNFQYGNRALLQSYLVGQPELREVLRAPNLEQLRQRIIASCHIGPMDSDETRAYIIHRLKRVGWTGRPQFDDAAFASVHDWTGGLPRRINMLCNRLLLSAFLDNTDQIDAARVDTVAREIREEIGGLLRPADPTEPQAPTITAPVQRTAPAAPEPPIQTDTASSLPVLRDVAEALTRAPAPPKPGEPGPLLCIAQTLEDRIALHPLMQKMRAYSGLPQPVLVGLEQLSSSAIANDPALAEIDLALLPDAQDERPSLAVWVNWLDQIFTTYRPAAVLTFADSDAALAAGLMAQRQKISHAHIESGLRHGQRADTQEIDRIVIDQLTDLHLTLGTGCADTLTHDGIPPASIRVVGNLRIDAVVQGLANAPDPKLFATEIGVPKTYLSNPQGYALLLLEDTEWATSRDKMIDLLANAKRLSRILPVIWPMPTALHSRLLQYGLSNSLRGSRVACVPELPFGQTLALLSKATCLLTDRANLQDASSYLAIPCLTLKDYCARTQTLKQGSNQLVGRDFRRIFQAMGDILEGDKKARPNPFEDDGKASERIAQALETWLMTQWENQVLETLETQA
>NC_014153.1|WP_013123663.1|2227441_2229049_+|polysaccharide-chain-length-determinant-protein,-PEP-CTERM-locus-subfamily
MNDLLRPLFNLLPGMWDRRWVGLLTAWVIMALGGIGVAMFHERYMASARVYVDTQTLLKPLMQGLTVQPNIDDQVAMVARTLLARPNLERLVREKHLAVDDGQPESVNRTVDQLLKSIKLGINARENLYSVSYVNSDPQVALGVVKDLVNMFLTSGIGGKQQDTQQALNFLDAQVADYGRQLSAAEQKLKDFKTQHPGYSGAANVDYYTRVNQASDQLSQLQGQLSAAIAARNAISGQMRGESPTISVTSPYMAAAAGPAAPGVPASVLDVDRRIQEQRARLDDLLQRYTNDYPDVISARQTLARLEAERKSRLKAAAEHPAQAAEPASIGANTISTANPAYQQLRVQVAQADANVASLQAQVGEAQARLAELRSQANKMPALDQQYAELMRGYDVIRKSYDDLVARRQSAGLTQSVDASSQLAVFRVVDPPRVEQRPLFPSKPMLIALLVFFALACGVAASFIVSQIMPTYHSPRHLRETIDRPVLGSISLLNSPEILSHDKRNNINLALGIAGLVLIGLLWAIWAHFTRQPGV
>NC_014153.1|WP_013123664.1|2229058_2230009_+|AAA-family-ATPase
MSTIEQAVKRLEELRTAGVDVLWKPESAAEVAPTAPSPSPFATAPAGAASTQPHTDPTQPTEAAKHTAKPQDMGTRSKQVEIDLNKLAAQGYIVPHATRSLLVDEFRVVKRPLLANVTGAASAKIDRPNLIMVTSSLPGEGKTFVAANLAMSIAAELNHTVLLVDADPSRSSLLERLGIAPAQGLIDKLLNPELDLSDLILATNVPKLAVLPVGTPNAQATELFASATMDLLLEEMAHRYRDRVIILDAPPLLPSAEARALSLHAGQILFVVQAGRTHQGTVHQSLSLLQDHPMVFTLLNQSRGPKAGSPYGYYAY
>NC_014153.1|WP_041608444.1|2230136_2237591_+|type-I-polyketide-synthase
MGTRQAGSGAVQYHSMEKPVERGVRAAFPFLVEIMHSPSNNGSPHSRLGDLTAIVPESLRKPFRLDLPTRGGLPSEIAMAAAAITLQRLCGPGAGLLVLSRQAAPFLLAALPDEAGLRVIERAGDELSERSAPPVPEAVDLIWLADPASEGDAASRYPSALILTLEPQQHALQILSSGLYPEEFVRSLLHIIDIVTRALQADPTQRVEQIALLDADQHAELLALNPDFRAAPASPSVQARFSEMQARHPEATAVRWHDGQWSYAQLNAQARAVAAALQTQGVAPGDVVALCLDRSPVAIASVLGMLMIGAAYLPIDSKFPPERVAFMVQDAGARLALVQPDTAALFPAKLQTLDPQDLLGNASAPQLSGDVPSAPDALAYVMYTSGSTGEPKGITIAHRAILRLVVDATFMPLDASTVMLHAAPLGFDASTLEIWGPLLNGGCCVLHDESIPTGPGIARSIAHHGVRSAWLTAALFNAIVDDDPHWFTGLSHLLTGGEALSVTHVRRALEALPQTALINGYGPTECTTFTATYRIPHALPPDTLTIPIGHPIQDTHVLIRSGTGALLPRGMVGELCVGGRGVARGYLNRAELSAERFVTDPLDVQGKLYRTGDLVRWRSDGALEFIGRVDGQIKIRGYRIEIGEIEAALAAQPGVQACAVALHTDPALGPQLVGYVVAQGGAPLDLGAVRRALAARLPDYMTPAHLIALARLPVTLNGKLDRKALPAPTRPAKAGTAAPAESPGVTQEVATVFAEVLGLDHVGPSDNFFTLGGNSLLVLRALAALRQRGHGELSVAAFFGDPTPRGIAAHIGGQVGIAANRLTAAHRSEPQGETLRDEPIAIIGMAGRFPGAATVEAFWDMLDEGREGIRFFRPDELDPAIPAALRADPAYVAARGVLQGVADFDAAFFGISPLEAELMDPQQRVFLELCWECMERAGHVPGQTATPVGVFAGMYNATYFQRHVSAHPDKVQRLGEFQVMLANEKDYIATRTANRLDLTGPAVSVHTGCSTSLVAIGQAVDSLHSGQCGMALAGGSSITCPPNSGYLYQEGSMLSPDGHTRTFDAQAQGTVFSDGAAVVLLKPLSAALADGDTIHALIRSVAINNDGGGKASFTAPSVDGQAAVAASALAAANVRPEDISYIETHGTATPLGDPVEVQALTRAFRQSTKRTQFCRVGSGKSNVGHTVIAAGATGVIKTALSLQHERIPATLHFHTPNPKLGLEDSPFIVNDRLTPWPRGAQPRLAGVNSSGVGGTNAHAILEEAPLRAPSSPAQGPFILRLSARSEGALAASAEQLAAHLATQRDTPLGDCAYTLRVGRKTFAHRLIVVADDAADAARALRDAQAPLRAQRRAPATPPPLALLFPGQGAQYAAMGSGLYGSLPEFHDAFDAALAAFAPHTKFDLKALLFGGDAAALQPTAVTQPATFCIEYALAQWWLQRGVEPSVLIGHSVGEFVAAVLAGVFSLEDAAALVALRGQLMQAQPPGAMLSVRLSASALQPYLTDDLDLAGENGPQASVVAGSFEAISRLQARLDADGLVSRPLQTSHAFHSAMMDAAVAPFEAAVRRVARHAPQRVIISTRTGQALSAEQATDPVYWARHLRETVRFSSAVQTALGTQPDLVCIECGPRGSLSTLVRQHARAGQAAPIALPSLHDAAASELHQLASAVGQLWTLGHDIPWFDAAEKRQRILLPTYPFERKRYWLDAAVAPQTSSQPAPQPAALQPAALPASASISAAPSLPISTTAAMTQAASRLPTLISRLNALFEDSSGVELADTDPTAAFVELGLDSLTLTQAALQIKKDFRLPITFRDLMERYRSVDALARHIDSQLPPEVAQPAAQPATQPAIAPQAAPQAPLAQPAGGFAMTQPAPSFAPQPIPAPLALAANAPFMQQLIAQQMQLMTQQLALLGGAPAAFAVPAVAEVPVAPQNIQAAAPAAVATPAPAPSPAHVEVAAPTADEEGPNANAKYDVKKAFGAIARIHTTPTGELSARQQARLDAFMRRYIERTKASKAYTVRHRPHLADPRVVNGFRPQLKEIIYQIVIARSAGCHMWDLDGNEYVDALSGFGMSLFGWQPPFINDAVRKQLDDGYDIGPQHPLAGEVAELICDLTGADRAALCNTGSEAVMGAVRVARTITGRSKIAIFAGAYHGIFDEVIVRGTKKGRSIPAAPGIMPNTSENVVVFDYGTPETLAALKERMDEFAAIVVEPVQSRRPDFQPREFLHALRELTAQAGTLLIFDEVVTGFRSHPGGIQALFDIRADLVSYGKVVGGGFPIGVIAGKRQFMDALDGGQWQYGDDSVPTVGVTYFAGTFVRHPLALAAAKAVLLHLKAAGPELQHTLTTSTAAMVDELNAYCREVGAPIVLKSFSSVWKIFFTEDHPMQDLLFAMMRSRGVHILDNFPCFFTTAHTPQDIAVIKTAFKEAVAELQEADFIPRHIDAAPAAFDASHPPVPGARIGKDPGGNPAWFVPNPEQPGKYLRLDA
>NC_014153.1|WP_013123666.1|2237598_2242551_+|non-ribosomal-peptide-synthetase
MDTSTATAVDYDPFADTAPVARVAPTTEAQREIWLACQLGGDATLAYNESITLHLRGAVDLPALTAAVRALPDRHDALRATLSADGEQLLIAERLNLDIPTDDLRGLTSEQGDDALKQAAAQAVAMPFDLQQGPLFRARLLRLADDHIALLLSAHHIVCDGWSFGVLVDEIGALYSARKGEAPEPEAPASFASFAQALSARQGSAEHQADEAYWLNRYASNPAVLELPCDHPRPATRAFDSKRIDHVLPANLVSAVRQLGAKSGASLFSTLLCSFGALLQRLSGNDEVVVGVPAAGQTLPGFETVVGHGVNLLPLRLIPDAAAPLAQSLPAVQSTVLDAFEHQHYTFGTLLQKLLIERDPSRVPLAPVMFNLDQAIDLRSFGHLQVSTVYNPRQAENFELSINAVPVVNGGLRLECQYATALFDEATVRRWLASYQALLTHLCAAPDAALGAIDIVTDADRQQLAQLNATSSPLPPGLLLHQLLHAQATRTPDATAQICGASPMSYAQLWAQAHRIAHALRARGVQRGSRVGLCLPRDADMLPALLGVLVAGAGYVPLDPSFPTSRLADMAEDADLALLIAKSTTADALPWPRAQSLWLDGDAVEIAAQPDTPPAADAARDATPESLAYMIYTSGSTGKPKGVMLPHRAVVNFLLAVAQRPGLTSGDMLLAVTTLSFDIAVLELLLPLAVGATVLLASREQAADGFALRDLLQAHPVTALQATPSTWRLLFSADWAGQSKLKALVGGEPLPADLAAQLQRSCGAVWNMYGPTETTVWSTCWRVQDSAAGIAIGTPLANTQVWVLDPRGNLCPVGVPGEIHIGGASVALGYWQREALTADRFVSDPFSNEPGARLYRTGDRGRWRNDGQLEHLGRLDFQVKLRGFRIELGDIETHLTQHPEVAQAVAMVREDTPGDARLVAYVVPRFAQVELDPAQLRKHLQQDLPAYMIPQHIVALQTLPLLPNGKIDRKRLPSPISGGRPVEAERRLPQTPTQKRVAAVMEQVLRLPGLALDDDFFSLGGHSLLAAQLAARLREQTGLDVQMRTVFDAPSIDGLSRWIDTHAQDDSAKVEAIAHRSEQTVAPASLQQGRIWFLEQLDPGLPTYNTPSAHRLRGALDVVALERALNAMVARQASLRTVIVEQDGAPLQVVAPELTVQLGEIHDLSALPPADREVELMKRLQARSAEAFDLGELPLFKLGLYRLAEDDHVLFFMPHHIIWDGWSFDLIYDEMAALYPAFAEGRAPDLAPLPVTYGDYAAWQRRWLETPDLQRQLGYWRDQLTPLPAPLNLPADRPRPKRMTGGGDTFWFSNPADWFASLHQFALQQNATPYMVLLSAFAALLWRQSGQTDLVIGTPVRGRPTVDLERVMGFFVNALPLRIRPDPRQSFASLVRQVREVMLSSYAAPDVPFEQLLRLVSPPRDDSRTPIYQAFFSYQDVRQRNTHWGTLEQENLKVYQPAAAEDVRLWFLNTPNGVMGGLTYNTDVFEAPRVAAWMAQYSQLLVDAMAHPETALADLPALRGTASVSSPASTASPVASPRAPAAAAPAADRLQTETERQLAALWAELLATPHIEPDDNFFDLGGHSLLVMQAVSRMEKLTGKRLGPRHYVFDSLRQIALEYDKTIQAAPSGKKSLFQRLFGKETSSSTHSAN
>NC_014153.1|WP_013123667.1|2242601_2243645_+|cupin-like-domain-containing-protein
MQQATPIGGGPDRARAQPLQTRPPLAIDVVRAQDLPYNEFLHEYVRKNRPVVIADSVREWPALSRWTPGYFRDKFGDQTVQVSYTKRMAMRDFVDAVEASTVDAPGPYLYRLFIHDHLPQLLADLRPQNAYAFAGRHASPLMPERWRRPDGFLKLLMGGVGSKFPVMHYDLEHAHAQITEIYGDKEFYLFPPDDGDKLYPRPTQKNWSQVDNPAAPDLSRFPRMAEATAYRAVLKPGQTIFIPMLWWHAARPLSISISVCTALMDRSNWPGFVEDVCDRSKNSAAKTALKRFYLKGAGSVMQAMENLQTATPLLAKRLKFPSALSPASPDFAKDPSETPMKFRLSVE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_7

2311189-2311316

Orphan

Consensus_repeat	Method
CCCCTCAAGGGGCGACACGCCCTTGGGGCGGCCCGGCGGGCGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_7

>merge|NC_014153|7|2311189-2311316|CRISPRCasFinder
CCCCTCAAGGGGCGACACGCCCTTGGGGCGGCCCGGCGGGCGTGGCCTGTGCCCACCCCGAAAGCCTGCGCTGCGCTTGGCTTGCCCCTCAAGGGGCGACACGCCCTTGGGGCGGCCCGGCGGGCGTG

>NC_014153|7|7|2311189-2311316|CRISPRCasFinder
CCCCTCAAGGGGCGACACGCCCTTGGGGCGGCCCGGCGGGCGTG	GCCTGTGCCCACCCCGAAAGCCTGCGCTGCGCTTGGCTTG
CCCCTCAAGGGGCGACACGCCCTTGGGGCGGCCCGGCGGGCGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013123720.1\|2304952_2306038_-\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270400
NC_014153.1\|WP_013123730.1\|2316508_2317972_+\|sensor-domain-containing-diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NC_014153.1\|WP_155816335.1\|2301817_2302366_+\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NC_014153.1\|WP_013123734.1\|2322642_2324355_+\|PTS-fructose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|236740
NC_014153.1\|WP_013123717.1\|2302372_2302963_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239489
NC_014153.1\|WP_013123732.1\|2319174_2321682_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NC_014153.1\|WP_013123731.1\|2318011_2319010_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_014153.1\|WP_013123725.1\|2310194_2311154_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270258
NC_014153.1\|WP_013123729.1\|2315324_2316311_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NC_014153.1\|WP_013123721.1\|2306172_2307255_-\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270400
NC_014153.1\|WP_013123726.1\|2311349_2312174_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223629
NC_014153.1\|WP_013123723.1\|2308932_2309505_+\|DUF615-domain-containing-protein	unknown	unknown	gnl\|CDD\|319991
NC_014153.1\|WP_013123728.1\|2313330_2315223_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|226229
NC_014153.1\|WP_013123727.1\|2312161_2313313_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NC_014153.1\|WP_013123735.1\|2324381_2325680_+\|carbohydrate-porin	unknown	unknown	gnl\|CDD\|335962
NC_014153.1\|WP_013123724.1\|2309482_2310106_+\|molybdopterin-adenylyltransferase	unknown	unknown	gnl\|CDD\|181837
NC_014153.1\|WP_155816275.1\|2301224_2301833_+\|DUF3106-domain-containing-protein	unknown	unknown	gnl\|CDD\|378633
NC_014153.1\|WP_013123719.1\|2303993_2304902_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_014153.1\|WP_013123733.1\|2321678_2322617_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NC_014153.1\|WP_013123722.1\|2307486_2308842_-\|metalloprotease-PmbA	unknown	unknown	gnl\|CDD\|182922

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013123720.1\|2304952_2306038_-\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270400	cd13682, PBP2_TRAP_alpha-ketoacid, Substrate-binding component of an alpha-keto acid binding Tripartite ATP-independent Periplasmic transporter and related proteins; contains the type 2 periplasmic-binding protein fold. This subgroup includes TRAP transporters that bind to ketoacids such as pyruvate and alpha-ketobutyrate, xylulose, and other unknown ligands. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
NC_014153.1\|WP_013123730.1\|2316508_2317972_+\|sensor-domain-containing-diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.56256e-39
NC_014153.1\|WP_155816335.1\|2301817_2302366_+\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	2.60023e-11
NC_014153.1\|WP_013123734.1\|2322642_2324355_+\|PTS-fructose-transporter-subunit-IIBC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	0
NC_014153.1\|WP_013123717.1\|2302372_2302963_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239489	cd03395, PAP2_like_4, PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	6.96015e-17
NC_014153.1\|WP_013123732.1\|2319174_2321682_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NC_014153.1\|WP_013123731.1\|2318011_2319010_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.18129e-103
NC_014153.1\|WP_013123725.1\|2310194_2311154_+\|extracellular-solute-binding-protein	gnl\|CDD\|270258	cd13540, PBP2_ModA_WtpA, Substrate binding domain of ModA/WtpA from Pyrococcus furiosus and its closest homologs;the type 2 periplasmic binding protein fold. This subfamily contains domains found in ModA proteins that serve as initial receptors in the ABC transport of molybdate in eubacteria and archaea. Bacteria and archaea import molybdenum and tungsten from the environment in the form of the oxyanions molybdate (MoO(4) (2-)) and tungstate (WO(4) (2-)). After binding molybdate with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. In contrast to the structure of the two ModA homologs from Escherichia coli and Azotobacter vinelandii, where the oxygen atoms are tetrahedrally arranged around the metal center, the structure of Pyrococcus furiosus ModA/WtpA (PfModA) has shown that a binding site for molybdate and tungstate where the central metal atom is in a hexacoordinate configuration. The ModA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.05794e-117
NC_014153.1\|WP_013123729.1\|2315324_2316311_-\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	0
NC_014153.1\|WP_013123721.1\|2306172_2307255_-\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270400	cd13682, PBP2_TRAP_alpha-ketoacid, Substrate-binding component of an alpha-keto acid binding Tripartite ATP-independent Periplasmic transporter and related proteins; contains the type 2 periplasmic-binding protein fold. This subgroup includes TRAP transporters that bind to ketoacids such as pyruvate and alpha-ketobutyrate, xylulose, and other unknown ligands. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
NC_014153.1\|WP_013123726.1\|2311349_2312174_+\|ABC-transporter-permease	gnl\|CDD\|223629	COG0555, CysU, ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones].	6.85936e-62
NC_014153.1\|WP_013123723.1\|2308932_2309505_+\|DUF615-domain-containing-protein	gnl\|CDD\|319991	cd16331, YjgA-like, uncharacterized proteins similar to Escherichia coli YjgA. Family of conserved uncharacterized proteins similar to Escherichia coli YjgA, which has been identified as comigrating with the 50S ribosome.	7.60735e-64
NC_014153.1\|WP_013123728.1\|2313330_2315223_-\|diguanylate-cyclase	gnl\|CDD\|226229	COG3706, PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms].	1.2293e-61
NC_014153.1\|WP_013123727.1\|2312161_2313313_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.9002e-79
NC_014153.1\|WP_013123735.1\|2324381_2325680_+\|carbohydrate-porin	gnl\|CDD\|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	1.26373e-98
NC_014153.1\|WP_013123724.1\|2309482_2310106_+\|molybdopterin-adenylyltransferase	gnl\|CDD\|181837	PRK09417, mogA, molybdenum cofactor biosynthesis protein MogA; Provisional.	1.1059e-130
NC_014153.1\|WP_155816275.1\|2301224_2301833_+\|DUF3106-domain-containing-protein	gnl\|CDD\|378633	pfam11304, DUF3106, Protein of unknown function (DUF3106). Some members in this family of proteins are annotated as transmembrane proteins however this cannot be confirmed. Currently no function is known.	2.29128e-30
NC_014153.1\|WP_013123719.1\|2303993_2304902_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.0187e-66
NC_014153.1\|WP_013123733.1\|2321678_2322617_+\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	1.10938e-111
NC_014153.1\|WP_013123722.1\|2307486_2308842_-\|metalloprotease-PmbA	gnl\|CDD\|182922	PRK11040, PRK11040, peptidase PmbA; Provisional.	1.83803e-170

>NC_014153.1|WP_013123725.1|2310194_2311154_+|extracellular-solute-binding-protein
MHPMKTLPLTLSALALAAACTTAQAETLTVFAAGTLGKTFTTLARGFEKLHPGVTVQPQFGGSVKMVKQVTVLHQPADIVAVADYSVIPKYMFKGDEGNKPTADWSIGFLGNAITFIYTPKSKGAKEINADNWWKILSEPGVQIGRSNPNTDPSGYQTLQMLDLAGRYYKQPDLEAKVLANSPESNMRDTETDLISALQLGQIDYLAIYRSDAVQHHMESIDLPPQINLSDPKFDADYAKASAKTKNGELSGRPIIYAVTIPTTAPHPKLAQEFIAYLLGPAGQNVIAANGFIPLKQPYAMNRDKVPADLRKLTVAWPR
>NC_014153.1|WP_013123724.1|2309482_2310106_+|molybdopterin-adenylyltransferase
MNPSPVSETSAADPVRIGLVSISDRASTGIYQDKGLPALRDWLGHALLNPVSFVERLIPDDRLQIANTLCELVDSEHCDLVLTTGGTGPAPRDVTPEATLDVADKEMPGFGEQMRRISLHFVPTAILSRQTAVIRAKTLIINLPGQPKSIAETLEGVRDAAGQSVVPGLFAAVPYCVDLIGGPYLETDPAVCVAFRPKSAQRPPRVS
>NC_014153.1|WP_013123723.1|2308932_2309505_+|DUF615-domain-containing-protein
MKFPHRPTGPAFDPPDDRPPSKSQVKRDMLALQELGEQLIGLPAHTIRQADLPEPLRDAVLEAQRITAHGGRKRQTLYVGKLMRSTDADAVRAVIAAATQDDRASVARMHALERWRDVLLADDQAQTEFLDKYPSTDAQQLRQLVRGARAEVGADKPPRLTRQLFQFVKAAIAAHDTPHHPADDEPLPSF
>NC_014153.1|WP_013123722.1|2307486_2308842_-|metalloprotease-PmbA
MGRFAYSKSQFQDLAQQALEQARKVGASDAQVEVSEGQGMSVGVRNGQIENVEHNRDKSLSISVFDGQRRGHASTSDFSAEAIARTAQAAFDIARYTAEDDCAGLPEVELLAIGRQQPQLDLYHPWDLTPQSAAKIALRAEKAAFAVDPRIRNSEGASVSAQESHFVLANSRGFCDGYATSSHSLSCAPIAGRGDDMQRDYWWTSECDPADLASPEAVGRYAAERALSRLKARKLSTRKCPVLFESPLASGLIGSFTHAISGGALYRKSSFLQDSLGQQVWADHIDLIEDPSLPKRRGSAPFDSEGVTTHKRSLVDGGVVQGYLLGTYSARKLGMQTTGNAGGAHNLLLQSRLTQAKDDLRAMLRKLDTGLFAIELMGHGVNYVTGDYSRGVMGFWVEGGKIRYPVQEITIAGNLRDMLRNVVAVGADTHTYGSKTTGSILIDGMTVGGAG
>NC_014153.1|WP_013123721.1|2306172_2307255_-|TRAP-transporter-substrate-binding-protein
MERRSFVKHAGLAGILAAGTAPAVMAQQSVRWRLASSFPNSLDTIYGAANVFAQKVKDLTNGKFEISVHAAGELVPAFGVVDAVQQGTVECCHTAPYYFFGKDPTFALGGTVPFGFNSRQMTAWMFQGNGLKLMREFYSQYNFLNFPCGNTGAQMGGWFRKPIKSLADMKGLKMRIGGFAGKVIERIGVVPQNIPGGDIYPSLEKGTIDAAEWIGPYDDLKLGFYKVAKNYLYPGWWEGGLELDLYVNQKAYNALPADYKAAVDAATAYAHVNMQAAYDAKNPPALKELVGKGAKLQGFPKDVMEAAYKAANDLYSELSANNPNWRKVYADWVKFRNDDILWFRFAENEFDRFMSTRKLT
>NC_014153.1|WP_013123720.1|2304952_2306038_-|TRAP-transporter-substrate-binding-protein
MERRSFVKHAGLAGILAAGSAPAVVMAQQSVRWRLASSFPNSLDTIFGAANIFAQKVKEASGGKFEISVHAAGELVPPFGVVDAVQQGTVECAHTAPYYFFGKDPTFALGCAVPFGMNSRQMSAWMYQGNGLKLMREFYANYNIISFPLGNTGAQMGGWFRKPIKSLADMKGLKMRIGGFGGKVMERIGVVPQNIPGGDIYPSLEKGTIDAAEWIGPYDDLKLGFYKVAKNYLYPGWWEGGPQLDLYVNQKAYNALSPEYKAIVELAASHAHINMQAMYDAKNPPALKELVGKGAKLQGFPKDVMEAAFKASNDLYNELSASNPRWKKVYTDWAKFRNDDILWFRFADNEFDRFMATRKFT
>NC_014153.1|WP_013123719.1|2303993_2304902_+|LysR-family-transcriptional-regulator
MSTNAFLSVLPEMVTFLRVAEFGSFSAAARQLGTTPSAVSRQVFRLEKHLGIQLILRTTRQLRLTAAGDAARVRCGELVAAAQAVMQVPQQIAGTPKGSICISAPKAFARHVLHSLLLQFLAQWPQVQLQLIATDHEVDPFREGVDLMIRVTRHPPEGFAARELMQVEQVLCAAPAYLAAHPAITHPSDLAAHSCLPLGEDAHDRCWRFRQGDTETEVVVQGRYAVNHSALRLEAMLAGLGLCTLPDYVARHALENRSAVQVLPDWNFLGNYGGSAYALYPPSRFVSPTLRALIDHLAAALE
>NC_014153.1|WP_013123717.1|2302372_2302963_+|phosphatase-PAP2-family-protein
MKLDPHALWYAWDGWNARLFLAINHAGDNPVWNNAARLGTALGDHHLLPVYLGLLLTLAMRWPRLIPLRSVLVYAWANLLLFVSIYGVLKPWAHFPRPLEVFGPQMVHVLGEPKFAHSFPSGHAAFAMVLAASLAFSLPRPWNVVLWLFALWVAWSRIAVGAHFPADVIGGAFLGALCVLVAHGLARLWIRGAKPA
>NC_014153.1|WP_155816335.1|2301817_2302366_+|RDD-family-protein
MPGPLSSRNGRTSSPKSMLSLNAPPLRRRLACLTYEGLILLGLSLVTAAVTLGLLHLLGLPQASATHRVILQVAEFVALTGYGAGFWSAGRQTLPMKVWKIALVTPSGAPLGLGRALWRAVLAWLWVIPALTLAAALHLSPGETGWLLAAGILLWAGASLLRKDRQYLHDVLAGTRLVPANG
>NC_014153.1|WP_155816275.1|2301224_2301833_+|DUF3106-domain-containing-protein
MERPLLLQSALLLCLFVALLFCVTPAHAAEAPPSWQHLSATQQHILAPLKADWSEFDHDRKKKWLDIAARYPAMSPQQQKTLQQRMNEWAHLSPEKRRLARENFLSTGKTPQQSRREAWEAYQKLPQAERERLKEEARHPKPHPGQVGKYLQEKQAAASHVQPVKPPVKPAPQPPLPASAPIPAKVASAAVPCADVLRCPAR
>NC_014153.1|WP_013123726.1|2311349_2312174_+|ABC-transporter-permease
MLRREARSPMFWVFWLIGATLLAFIALPLLALLLHPTLGDLRQVAAMADVRSAIGLSLGAALFSTVLAAMFAVPLAYVLARQQFRGKSAVEALVDLPLTIPHTIAGIALLLVFSRGGWLGAPLAHIGLEFWGTFAGIVLAMSYVGLPYAVNAARGGFEAVDLQIERAARIQGAAPWEVFRRVTLPLARQGIGTGLTLCFARAIGEFAAVVLLAYYPMTAPIRIYDLFLQSGLRQSVAASVLFLLVVMALFWGLRLLASARAPQSAQDRQKAWLH
>NC_014153.1|WP_013123727.1|2312161_2313313_+|ABC-transporter-ATP-binding-protein
MAALTQRTVLATPAVTGSAHGAPGALRLRGLQWGIGAWQSAVVDLQVPPGQTLVLLGHNGAGKSVLLDTLAGFLPARAGQVQLGAQDLTAQPPEKRRIGYMFQRDALFPHWTIARNLQFGRGAQADLDPLLDALDLRPWLNQYPHQLSGGQRQRVALARALVGAPELLLLDEPFSAIDPEARPSLRRTLAALLRERAITTVLVTHDPVDARLLGDLVGVLDGGRLLQAGTPQQVFERPADLPTARLAGVDNLWPLQVLAQSRLGAQDVLSLGIEAQPVLYWRGTLPAGAELQPGARVTLAVRAEAVHPCPASALVTQDDDSLTLTARLIEARCEGPLWRLRCALPCGLEAETYALPTLWRELALEIGGTLGLRIRQADLHLLV
>NC_014153.1|WP_013123728.1|2313330_2315223_-|diguanylate-cyclase
MPASPLTDPEILQALTAENRLLPSPSAVALELMRALERRDLGMRDIANIARKDPALVARMIQLANSAIFAGMRPAVAIEEAVLRIGTGGLARLAIALSLMQASKATNIEGFDLRRFWMTSIQRGLVFQYLSQRVGKMPSAEAFSLGLLADVGQLAMAVSLGAQAVYIGAEGSVQALLAQQLQQYGYDQGDASAVLLAHWGFPQTLAQAVRIRPQTPGAAGSREAQLGECVALSRSLQLRPGSVAADAGQMRSLAEHLHLSESDLQGVLASAAQDMAGMAAVFEMKLEQAEVDTEFDRLRRALATPPLLDEPIADEVLIVSKDAALRLGLRQALESAGHALAEAATPAEAFEIVQIQGPRVVVLDWADGDSVAALCRSLRTERGPRIYLLALSRDMEQHAVLNALDAGANDVLFAPVLPQMLIAKVQTGARATRVLAAAEAERSHGLRTLRTLEQRNAELLQAAGTDELTGVGNRRALDAFLPPLFAQAAAEGQPLACLMFDLDEFKRINDRLGHDVGDQALRAVGRVLRQQSRGMDFVARVGGEEFLMLCPQTTEEAAMRVAERIRAAIAVPQADLPPLSVSVGVALGAAGFADAASLIRAADQALLQAKRLGRNRVCLAPTASSAAARN
>NC_014153.1|WP_013123729.1|2315324_2316311_-|aldo/keto-reductase
MQYRQLGADGPNVSALGLGCMGMSEFYGQGDDAESIATLRRALDLGVNFLDTADMYGVGRNEVLVGRAIKGRRDEVFLATKFGNMRGPNGEFLGVNGRPDYVRQSCEASLKRLGVDVIDLYYQHRVDPEVPIEETVGAMADLVRAGKVRWLGLSEAAPATIRRAHAVHPISALQSEYSLWSRDPEGVLLDTVRELGIAFVAYSPLGRGFLTSQIKSLDDLPEDDWRRRSPRFQPETFARNLRLAETVRQMAEAKNCTPAQFALAWLLAQGDDVIAIPGTKRRRYLEENMGALRVRLSTADLIRIHQAVPPGAASGERYPEAGMQAVNR
>NC_014153.1|WP_013123730.1|2316508_2317972_+|sensor-domain-containing-diguanylate-cyclase
MTALTLHPGELANMFELAPVSLWVEDFSALHQLFKQWRAEGVSDLRAWLHEQPARVAECSARIKVLQVNRRTLDLFEARDLAHLVANLDLVFRDDMHSQHLEELVQLWQGATRYSSQTVNYTLSGRRLDILLNAHVLPGHEQSWSRVLFSVEDLTDRLRAERQLHASEQYARGLFEHSPVSLWVEDFSAVRSLLSMLREQGISDFPTFLRVHPEFIDRCMQEIRVLDVNHQTLSMVGASDKPHLLRNLQHVFRDDMRVHFADQLIDLWNGKLTQQREVINYSLKGQPINAHMQFAVMPGHEDDWAQVLVSLTDITARKKAEAYLEFLGNHDVLTSLRNRTFYVDEINRLERKEAWPVSVIMLDLNGLKSVNDELGHAAGDGLLRRAGEVLAKLVDKPQVAARVGGDEFVLLLPDADASAAKTLSQRLLELVDLNNQFHQSPRLSFSMGIATCMPGERLEAAIHRADQQMYAEKRAYYLKSDIDRRHD
>NC_014153.1|WP_013123731.1|2318011_2319010_-|LacI-family-DNA-binding-transcriptional-regulator
MSSSIKDVARVAGVSVATVSRALSGAAAVSPALTERIQQAIRETGYRPNLSARRLRSQDSGTIGLIVADIRNPFFTAVSRAVEDAAYSAGLRVILCNTDENPDKEAMYLNLMEEERVTGVIFAPTRQTADQLNAQDWSFPIVLIDRVGARGGQDAVALDNAAASALLVEHLHAQGCRRIAGVFGNASSSGVERHDGYVAAMFRLGLPPRSTFVPPQALAAEEAVAHWLRETARPDALIASNGLLLMGLVRAVRHAGLQIARDIAVAGFDNESWTEIVEPGLTVIEQPVDDIGRNAMQLLSERLKNPDLPARKLLLSGRCIERGSTRCGGAAA
>NC_014153.1|WP_013123732.1|2319174_2321682_+|phosphoenolpyruvate--protein-phosphotransferase
MSVTTPQDLLTDARIRLGARPETKEDAIREACQLLIASGCVAPEFTASVLEREKVANTFLGHGVSIPHSLGKDRDLILRDGIAVLQVPQGVEWNPGQTARLVVAIAAKSDSHIAILRRLTRLMQDDMRLSALFSTLNPSELASALRDDTASAATSPAVDLAQTLDWVLPYPAGLHARPASVWVEAARKSGVRLQVRHGNDTADPRNLVALLSLGLRQGDLLHLSADGEHARDALDRFRQLLDSLTLQERADAQRAAVQTVPTAGAWVPPGQPVAVPGMPASPGLAIGVLHVLAKSHAEIPDLPVPLDQGADQLNNALIATDQQLAALADDTARRLGEAEARIFKAQRELLKDSDLITLACQIMVEGHGVGWSWNSAIDRMACKLAALGNPVLAGRATDLRDVGRRVLMLLEPTLQLGSLQDLPDAPCILVSDDLSPSDTAAIDMTRVVGLAIAQGGPTSHTAILARTLGLPAMVGAGPALQALRSGTQGVIDGVGGKLYLDPSEADLASARSWMTSEAARRDAQKAERSQAARLLDGHVVAIGANVNLPSQVPMAIDEGAEGVGLMRTEFLFLERGETPDEAAQFAIYRDMIEALGNRPLIVRALDIGGDKQVAHLHLPQEANPFLGVRGARLLLRRADLLEPQLRALYRAAKLGADLSIMFPMITSVDEVLTLRAVCERIRAELDAPQVPLGIMIEVPAAALQADVLAAHVDFFSIGTNDLTQYTLAMDRQNPELAPQTDSLHPAVLRLIRATVEGAARHGRWVGVCGGMAGDPFGAALLTGLGVNELSMTPRDIPAVKARLRASALTELQQLATRALAAESAQAVRALNGEAA
>NC_014153.1|WP_013123733.1|2321678_2322617_+|1-phosphofructokinase
MNSPVVTVTFNPAIDETITLDALRPGEVHRARSVRFDAGGKGVMVAGCLADWGQPVIATGLLGSDNTALFNALFAAKGIEDRFIRHPGQTRTNIKLLDPHATTDINLPGADIPVALTCQVHETVLRYADAKTLVVLSGSLPAGFPAQTYAELIGALAEHGIRTVLDTSGAPLGAALQARVPSVIKPNREELEAWAGHALPTRGDLIRTAQDLLARGVELVAISMGAEGALFISPTAALHASLPPLQPMSTVGAGDAMVAGIVAALAERATLEHIARLGTAFAHSKLGQIGPNLGPRDQVQHLAAQVQLQLER
>NC_014153.1|WP_013123734.1|2322642_2324355_+|PTS-fructose-transporter-subunit-IIBC
MSPLFACVAAQDRTVAGVLAAEALRLAAAKRQQAIDIEVVTAEGVLNPLTRTQTAAGGTLLAVGPVNAADPRFAGLRVVSASIEEVLANVNTVLDHALAPTPPDKSRSTTARIVAVTSCPTGIAHTFMAAEAIEQAAKALGHLVKVETQGSVGSQNTLTDDDIAQADVVLISADRQVDLSRFAGKRVLQASTKPAIQDGQALIRRALAEAQVLSPAGDASFEASGKREKAAVLRAGPYKHLMTGVSFMLPFITAGGLLIALSFALGGIYVFKPEHAGTLGYELFQIGAKAAFALIVPALSGYIAYSIADRPGIAPGMIGGMIASSIGAGFLGGIVSGFIAGYGTDWFNKHLKLNRHVEGLKPVLILPLLGTLLTGLLMIYVVGTPVAHALAWLTDWLKSMQGASAILLGLMLGAMMAFDMGGPVNKAAYTFATGLLASQIFTPMAAVMAAGMTPPLALALATRVFPSRFTLDEREAWGATGLLGLSFITEGAIPYAARDPLRVIPANMIGSAVAGAISMVAAVQLRVPHGGVFVLPIPNAVSHLGMYVIAIVAGTVVSAVLLGLLKKPVA
>NC_014153.1|WP_013123735.1|2324381_2325680_+|carbohydrate-porin
MMLSTLFKPTCLCAALLLMSSAAAQAAQSTHTPGQYDLGNGLTFSANYTGEAAANTTGGLRQGSAYAGQLFLGADLDLQKMLGWNATSVHIAVTQRHGQSLSNEAIGNNTSVQEIYGTQNLHLAYFTVEKKFFGGRLEIQGGRTVANIDFLNSPLYCNFQSNSACGNPTFVFKNSNFTYFPASSWGGYAKGWVTDKFYAKVGAYEVNPNDKRPNDHGIDWSTKDATGVVVPWAMGYATTFANDTHPRDYEIGGWFDRSKYTDPLLDANGDYAVLTGQPYRTDRNRSGAYVRFSQMVWRPDMNSQRGLTLFGVAMTNLTGRVNESSFLELGAVMQGPFPGREQDTLGFVINQQRFSSLALQNIRVARASVGASTDIPGSETMMELAYGYQLSPGIRLSPNLQYILHPDQQAEPFRTSNIPNAFVIGLKFTVAL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_8

2887174-2887280

Orphan

Consensus_repeat	Method
AGAAAACGTAGGGCCGCCCCAAGTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_8

>merge|NC_014153|8|2887174-2887280|CRISPRCasFinder
AGAAAACGTAGGGCCGCCCCAAGTTTTCTCATCCCCCTTGGGGGGCCTGACGCGAACGCGGCAGGTCTGGGGGCGCTCTCAAGAAAACGTAGGGCCGCCCCAAGTTT

>NC_014153|8|8|2887174-2887280|CRISPRCasFinder
AGAAAACGTAGGGCCGCCCCAAGTTT	TCTCATCCCCCTTGGGGGGCCTGACGCGAACGCGGCAGGTCTGGGGGCGCTCTCA
AGAAAACGTAGGGCCGCCCCAAGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013124186.1\|2887467_2887686_-\|DUF1289-domain-containing-protein	unknown	unknown	gnl\|CDD\|377738
NC_014153.1\|WP_013124182.1\|2882287_2883436_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380565
NC_014153.1\|WP_013107100.1\|2880586_2881102_+\|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase	unknown	unknown	gnl\|CDD\|179953
NC_014153.1\|WP_013124180.1\|2879953_2880526_-\|Holliday-junction-branch-migration-protein-RuvA	unknown	unknown	gnl\|CDD\|234645
NC_014153.1\|WP_013124188.1\|2888206_2889154_-\|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl\|CDD\|180206
NC_014153.1\|WP_013124187.1\|2887682_2888195_-\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239825
NC_014153.1\|WP_013124178.1\|2876302_2877856_-\|cytochrome-c-peroxidase	unknown	unknown	gnl\|CDD\|224771
NC_014153.1\|WP_013124192.1\|2892896_2893925_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|273075
NC_014153.1\|WP_013124181.1\|2881214_2882246_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293840
NC_014153.1\|WP_013124194.1\|2894748_2895276_-\|DNA-damage-inducible-protein-DinB	unknown	unknown	gnl\|CDD\|225200
NC_014153.1\|WP_013124184.1\|2884142_2885693_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NC_014153.1\|WP_013124183.1\|2883538_2884126_-\|crossover-junction-endodeoxyribonuclease-RuvC	unknown	unknown	gnl\|CDD\|234587
NC_014153.1\|WP_013124189.1\|2889167_2890118_-\|D-isomer-specific-2-hydroxyacid-dehydrogenase-NAD-binding-protein	unknown	unknown	gnl\|CDD\|240641
NC_014153.1\|WP_013124191.1\|2892222_2892900_-\|DUF4126-domain-containing-protein	unknown	unknown	gnl\|CDD\|379253
NC_014153.1\|WP_041608740.1\|2886009_2887005_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NC_014153.1\|WP_013124190.1\|2890114_2892196_-\|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|227111
NC_014153.1\|WP_013107110.1\|2885736_2885982_-\|Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|179348
NC_014153.1\|WP_013124195.1\|2895304_2895703_-\|PIN-domain-nuclease	unknown	unknown	gnl\|CDD\|350327
NC_014153.1\|WP_013124193.1\|2893951_2894752_-\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|235664
NC_014153.1\|WP_013124179.1\|2877971_2879720_-\|alkaline-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|293737

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013124186.1\|2887467_2887686_-\|DUF1289-domain-containing-protein	gnl\|CDD\|377738	pfam06945, DUF1289, Protein of unknown function (DUF1289). This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	3.58446e-19
NC_014153.1\|WP_013124182.1\|2882287_2883436_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380565	cd06342, PBP1_ABC_LIVBP-like, type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.	5.52173e-131
NC_014153.1\|WP_013107100.1\|2880586_2881102_+\|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase	gnl\|CDD\|179953	PRK05174, PRK05174, bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase.	3.02583e-125
NC_014153.1\|WP_013124180.1\|2879953_2880526_-\|Holliday-junction-branch-migration-protein-RuvA	gnl\|CDD\|234645	PRK00116, ruvA, Holliday junction branch migration protein RuvA.	6.24123e-92
NC_014153.1\|WP_013124188.1\|2888206_2889154_-\|hydroxymethylglutaryl-CoA-lyase	gnl\|CDD\|180206	PRK05692, PRK05692, hydroxymethylglutaryl-CoA lyase; Provisional.	3.61452e-180
NC_014153.1\|WP_013124187.1\|2887682_2888195_-\|YbaK/EbsC-family-protein	gnl\|CDD\|239825	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS). While ProX and ProRS-INS hydrolyze misacylated Ala-tRNA(Pro), the E. coli YbaK hydrolyzes misacylated Cys-tRNA(Pro). A few CD members are N-terminal, YbaK-ProX-like domains of an uncharacterized protein with a C-terminal, predicted Fe-S protein domain.	4.41485e-53
NC_014153.1\|WP_013124178.1\|2876302_2877856_-\|cytochrome-c-peroxidase	gnl\|CDD\|224771	COG1858, MauG, Cytochrome c peroxidase [Inorganic ion transport and metabolism].	3.10254e-63
NC_014153.1\|WP_013124192.1\|2892896_2893925_-\|biotin-synthase-BioB	gnl\|CDD\|273075	TIGR00433, biotin_synthase, biotin synthase. Catalyzes the last step of the biotin biosynthesis pathway. All members of the seed alignment are in the immediate gene neighborhood of a bioA gene. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	1.73442e-168
NC_014153.1\|WP_013124181.1\|2881214_2882246_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	5.16658e-62
NC_014153.1\|WP_013124194.1\|2894748_2895276_-\|DNA-damage-inducible-protein-DinB	gnl\|CDD\|225200	COG2318, DinB, Uncharacterized protein conserved in bacteria [Function unknown].	3.92881e-32
NC_014153.1\|WP_013124184.1\|2884142_2885693_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_014153.1\|WP_013124183.1\|2883538_2884126_-\|crossover-junction-endodeoxyribonuclease-RuvC	gnl\|CDD\|234587	PRK00039, ruvC, Holliday junction resolvase; Reviewed.	3.94613e-78
NC_014153.1\|WP_013124189.1\|2889167_2890118_-\|D-isomer-specific-2-hydroxyacid-dehydrogenase-NAD-binding-protein	gnl\|CDD\|240641	cd12164, GDH_like_2, Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family. This group contains a variety of proteins variously identified as glycerate dehydrogenase (GDH, also known as hydroxypyruvate reductase) and other enzymes of the 2-hydroxyacid dehydrogenase family. GDH catalyzes the reversible reaction of (R)-glycerate + NAD+ to hydroxypyruvate + NADH + H+. 2-hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.2245e-121
NC_014153.1\|WP_013124191.1\|2892222_2892900_-\|DUF4126-domain-containing-protein	gnl\|CDD\|379253	pfam13548, DUF4126, Domain of unknown function (DUF4126).	5.48106e-48
NC_014153.1\|WP_041608740.1\|2886009_2887005_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	7.94093e-124
NC_014153.1\|WP_013124190.1\|2890114_2892196_-\|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	gnl\|CDD\|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NC_014153.1\|WP_013107110.1\|2885736_2885982_-\|Fis-family-transcriptional-regulator	gnl\|CDD\|179348	PRK01905, PRK01905, Fis family transcriptional regulator.	6.15698e-34
NC_014153.1\|WP_013124195.1\|2895304_2895703_-\|PIN-domain-nuclease	gnl\|CDD\|350327	cd18760, PIN_MtVapC3-like, uncharacterized subgroup of the VapC3-like nuclease subfamily of the PIN domain superfamily. The VapC3-like nuclease subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of various Mycobacterium tuberculosis VapC toxins including VapC3, VapC11, VapC15, VapC21, VapC25, VapC28, VapC29, VapC30, VapC32, VapC33, VapC37, and VapC39. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.47018e-63
NC_014153.1\|WP_013124193.1\|2893951_2894752_-\|enoyl-CoA-hydratase	gnl\|CDD\|235664	PRK05995, PRK05995, enoyl-CoA hydratase; Provisional.	2.09409e-112
NC_014153.1\|WP_013124179.1\|2877971_2879720_-\|alkaline-phosphatase-family-protein	gnl\|CDD\|293737	cd16013, AcpA, acid phosphatase A. Acid phosphatase A catalyzes the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at low pH. AcpA hydrolyzes a variety of substrates, including p-nitrophenylphosphate (pNPP), p-nitrophenylphosphorylcholine (pNPPC), peptides containing phosphotyrosine, inositol phosphates, AMP, ATP, fructose 1,6-bisphosphate, glucose and fructose 6-phosphates, NADP, and ribose 5-phosphate. AcpA is distinct from histidine ACPs and purple ACPs, as well as class A, B, and C bacterial nonspecific ACPs.	4.16002e-122

>NC_014153.1|WP_041608740.1|2886009_2887005_-|tRNA-dihydrouridine-synthase-DusB
MRLGRHLLPNRVFAAPMAGVTDRPYRRLARQLGAGYCVSEMVTSRADLRDTLKTSRRANHDGEAAPIAVQIVGTDPEQIAEATRYNLERGADIIDINMGCPAKKVCNRWAGSALMQDEDLAARLVEAAVAAARPFDAPVTLKMRAGWCEAARNAPRIARRAEAAGAAMLVVHGRTREQGYGGEAEYATLAEVKRSVGIPVVANGDIDSPQKAAAVLRQSGADAVMIGRAAMGRPWLFGQVAAYLEHGVLLPDPAPEQWRDWLFAHLDDHYALYGEAIGVRTARKHVGWYVAALPEGETFRRQFNTLGSAAEQLAALRGFLDSGSRAAPLAA
>NC_014153.1|WP_013107110.1|2885736_2885982_-|Fis-family-transcriptional-regulator
MPAVPRKTTLEQCVVDSLEAYFNDLGGSEPHGIHAMVLAAVEKPLLATVMKHAEGNQSLAARWLDINRNTLRKKLAEHKLL
>NC_014153.1|WP_013124184.1|2884142_2885693_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MQALISVSDKTGVLDFARDLHALGVRLLSTGGTAKMLQGAGLPVTEVADYTGFPEMLDGRVKTLHPKVHAGLLARRDLPEHVAQTDAHDLPAIDILCVNLYPFEATVAKPHTLDEAIENIDIGGPAMVRSGAKNYHHVAVLTDPADYAVVVAELRAAGQVSDATRFRLSVAAFNRIAQYDAAISNYLSALQDDGTRASFPGQFNLSFVKQQDLRYGENPHQSAAFYVEPGAREASIATARQLQGKELSYNNIGDADAALECVKQFDTAPACVIVKHANPCGVAYGTSLLDAYERAYKTDPESSFGGIIAFNGELDGATAQAIVERQFVEVIIAPKVTQAAIDICAAKKNVRLLECGQWPAQPGARLDYKRVNGGLLVQDADLLLSGDIQVVSQRQPSADEMRDLLFAWRVAKFVKSNAIVYAMDNATIGVGAGQMSRVNSARIAAIKAEHAGLPVPGSVMASDAFFPFRDGIDNAAQAGIKAVIQPGGSMRDAEVIQAADEHGMAMVLTGMRHFRH
>NC_014153.1|WP_013124183.1|2883538_2884126_-|crossover-junction-endodeoxyribonuclease-RuvC
MRILGIDPGLNTTGYGVIDAHGQRLGYQASGAIRIPKGTLPERLKTLFDGVSEVARLADAEVAVVEIVFVNVNPQSTLLLGQARGAAIAALVAQGLPVVEYTALQLKKSIVGYGRASKSQIQEMVMRLLALPGQPGPDAADALGLAICHAHAQRGLAALHRASSPANVGTADVASGKLSAAQLRGMRVRGGRLIG
>NC_014153.1|WP_013124182.1|2882287_2883436_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MTSSLLLTGVSLALFAGLGLSAQAAEPRVVLGVAVPLSGPLAASGQDAVNGVQMALNQLNAEHARIGGKSVRWAMDAEDDQGLPTQATLVAQKLVDEGVSGVVGHQTSGCTFPAARIYARAGIPQITPSSTSPKIAEQGYKTFFRLIANDNALGAGLAEYAHDALHVQRVAVVDDRTAYGQGLADVFSAKAKKLGMDVVDREYTDDKATDFSAILTRIKADHPQVIFYGGMYSQAGPLVRQMRQIGITARLMGGDGICAPIMAKVAGDAVNGTICAQGGAPLSELPKGQAWKARYDAEFGAAAFQLYSPNAFDAAMVLAHAMMKAGSSDPKVCLPYIRHIDYDGVTDSDIHFTATGELADPSITLSEFEHGVKVPLAVEQVK
>NC_014153.1|WP_013124181.1|2881214_2882246_+|MBL-fold-metallo-hydrolase
MRPSTLPDLQRRRLMGWGLSAAGLAAAGAAAPHLAAFAADAVDFIRGPKVPDVPFTQISDHVYVIYAADGFPTESNQGMMSNITAVKTAKGVVILDSGASVQIGEMVIRQLPKVSDKPVVAVFNSHYHGDHWLGNDAFVSAYGQDLPIYAMPQTREQILGATGTEWQQAMLKWTNQSSAGTRIVAPNRDVKHGDVFDFGDVTLRAHHYGTAHTPSDVCLEVVQDKLTYVGDVMMNRRIANMDDGSYPGSLNYMDKLAQNIPGSNWLPGHGHAGQAVMVWQRELFAAIWEHAQQAARDMAGPEAAIAVAKADPRVASKAKETAGWDNNIGKYISLAYLEAEQKV
>NC_014153.1|WP_013107100.1|2880586_2881102_+|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase
MTRPSSYSKEDLITCGEGRLFGPGNAQLPLREMLMMDRITRIASEGGTYGKGVIEAELDIHPDLWFFGVHFQGDPVMPGCLGLDAMWQLVGFYLGWMGGLGRGRALGVGEVKFTGQVLPTAKLVQYRIDLKRVINSRLVMGIGDGAMLVDGREIYTAKDLRVGLFTSTEGF
>NC_014153.1|WP_013124180.1|2879953_2880526_-|Holliday-junction-branch-migration-protein-RuvA
MIGRLHGTLLDKSPPQILLDVGGVGYEVDVPMSTLYDLPAVGHAVTLLIHTVIREDAHLLYGFATAGERSTFRELLKISGIGPRIALAVLSGLSVSEIAQAVTQQDAVRFTRVPGIGKKTAERLLLELKGKLGADLGGAATAAAGSASDVLQALIALGYSEREAAAAAKALPEGCSVDDGIRQALKSLAR
>NC_014153.1|WP_013124179.1|2877971_2879720_-|alkaline-phosphatase-family-protein
MLRKTLLASAVAVATVTLAACGGGSNSVAASPTVPGTSYTAARALATATPIKHVVVLYQENVSFDHYYATYPTATNPAGEPAFTAKAGTPAVNNLVSANLLSNNPNFNNTANGTDAAEPYRLDRTQAATADQNHAYTAEQQAYDGGKADLFPKYTGAATTGGVGAFGTKGQVMGYYDGNTVTALWNYAQNFALSDDAYTDTYGPSTPGALEAVSGQTNGVQLVATTDQPFTLSKYSYYISDGQGGYGLINDVDPAYDICSSPTNQVSMSGKNIGDLLNGKNISWGGFMGGFNLGATNPNGTTGCKRSTFSPVVNSTVGDYIQHHNWFQYYKSTANPTHARPSSTLAIGHTLETDNKTADPANHEYGLQDFFAAVKAGNMPAVAYLKAPAFEDGHAGYSDPLDEQAFVSQVVNFLEQQPQWSSTAVIVTWDDSDGWYDHAFANTTNPSFDSQADQLNGAGVCGKGTPLSGVNGKPVNGRCGPGTRIPFLVISPWAKTNYVSNTPISQASIVRFIEDNWLGGQRLGGGSFDATAGSINNLFDFTKSVGSAPKVFIDPAQGTVLSAPPAGSLTPQFNVSLFTKQS
>NC_014153.1|WP_013124178.1|2876302_2877856_-|cytochrome-c-peroxidase
MSVTSSTPAVASSAAVQAPASKPRRSHWARRLAIALVVGLAGGGGALAWGMHEQPSIPPVVWLQHPVQSFTFALGGNPHPVQLALPPQQPLSAVAQLGRQLFFDTALSASGKQSCASCHDPANGYNPPPGRPKAGFAPLGGSEPTASVGAQQSPPPGSGAVMLGGPNMTSPGFRPPPSLAYLYRQQPFSIGPDNEENETITLQQLAALGQTSQRAKKTAQSTAQSVQNLVPTGGLFWDGRVNTLQQQAGGPLFNPVEMDAGTPQRVAAIIERQPYAKTFLQLFGPNVFADPKQTVSEALFAIARYQIEDPQFHAFNSKYDAWLQGRATLTSQEMRGYLAFNDVNKGDCAACHLDQPTKDHLPPLFTDTQYEALGVPRNPQIPANQNPHYFDIGLCGPFRTDLKNQTAYCGMFLTPTLRNVAQRPVYFHNGVYHSLKQVLDFYNFRDVQPGRIYPTVGGQVRKYDDLPPQYRANVDVTDPPLNRKLGEQPAMTAQDMRDIIAFLHTLNDGYTPLKPVS
>NC_014153.1|WP_013124186.1|2887467_2887686_-|DUF1289-domain-containing-protein
MTVPSPCINICTLDAASGLCLGCARTLQEISDWSNLDDAGKRAVWARIAERRAQGFAPEQPIALKPGPVRAR
>NC_014153.1|WP_013124187.1|2887682_2888195_-|YbaK/EbsC-family-protein
MQTTAISSPSSSPSDSVQRVIDALAALGHAEPPVMLDAAARTAEQAADALGVALGQIAKSIVFCHADSGRAVLVVCAGDRRVDEKAVAAQVGHLARADADFVRAATGFAIGGVSPVGHTQPPIALVDNSLWRFDRIWAAAGHPHAVFPLRPEDLPRWLGVAPSAVSRAPQ
>NC_014153.1|WP_013124188.1|2888206_2889154_-|hydroxymethylglutaryl-CoA-lyase
MSTLNHLPKFVEVVEVGPRDGLQNEANPVPVAVKVDLIDRLSAAGLPNVEAAAFVSPKWVPQMAGSSEVMAGIRRRPGTVYSALVPNMKGMEAALAAGVGEVVVFSAASEAFAQKNINCSIAESIERFRPVAEAAKSAGVNLRGSISVALGCPYQGAVEPSAVAEVVRRMADLGCDCIDIADTIGVGTPGAVQAVFEASAAAFPMQKLAGHFHDTYGQALANILAALQMGVASFHSSVAGLGGCPYAKGATGNVATEDVLYLLHGLGIDTGVNLRAVVEAGDFITRAINRPNNSRAGKALLAKWAAEQGEPACTA
>NC_014153.1|WP_013124189.1|2889167_2890118_-|D-isomer-specific-2-hydroxyacid-dehydrogenase-NAD-binding-protein
MRLAVWDPDEPFRRWRDALMQHAKEIGLAIDVIDAPSDPDAQAEFALVWRPDADWLAGQMGLRAVFNLGAGVDAIAPALHRLHPGVPLIRLEDAGMGRQMADYVAEGVLHAYRRMTDYAAQQAKARWEPLPLPPRASFSVGFLGLGQMGAAAARRVAAMDFPILACSRSGQSRFAAELGCAIYALDRLDEFLAQTRVLVVLLPLTADTRGLLDYAALSRLPQGAHLINASRGAVIDQADLLDLLHGGHLASALLDVFATEPLPAADALWSHPRVRITPHVAAQTLVGPSAAQVMRKIAAIERGEKPGGVVDMRLGY
>NC_014153.1|WP_013124190.1|2890114_2892196_-|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha
MFSKILIANRGEIACRVAATCRCLGIRTVAVYSEADAQAAHVAACDEAVCIGPAEAAQSYLRDERILQAARDTGAQAIHPGYGFLSENAGFARQCAEAGVVFIGPPPEAMQAMGLKAESKRLMQTASVPLVPGYHGAEQDAALLRAEAARIGFPVLIKASAGGGGKGMREVQRVEDFDAALASCRREAQSSFGNDAVLIERLVRNPRHIEIQIFADQHDHVLWLFERDCSMQRRHQKVIEEAPAPGLPDALRREMGEAAVAAARAVGYVGAGTVEFIVECSEGGVPQRFYFMEMNTRLQVEHPVTELITGLDLVEWQLRVAAGEPLPITQAEVRCSGHAIEARLYAEHPEAGFLPSTGQLRRLALPPHVAFGAVGAEGIRVDSGVFEGDTITPFYDPMIAKLIAWGETREQARRRLRQALAATRIAGLQTNAQFLHRLLGVAEFAGGVLDTGLIAREHEALLAPPSIPQSLACAAAIGAMLEDERAQQSADPWSPWSPWSICDGFTNGVLPPRVFRFDSPWGVLACTLLTATGQPLRIQTPGSPQPQPFACTARAVRATRDVREFALVLTLGEERAQMSVVRLGETSFQVFSGGELVTLQALGADLGSSDGGLAGGRLTAPMPGRIIALHVQAGDTVQAGAPLLVLEAMKMEHTLSAPSAGQVSEVLYAVGDQVSEGVELLRIEALKTEGSPA
>NC_014153.1|WP_013124191.1|2892222_2892900_-|DUF4126-domain-containing-protein
MTPSSLDTLQLLALAAALGWASGLRAFLVMFAVGAAGLAGWVQLPSGLQGLASPVAVGITGFLAFLEFVGDKIPGVDSLLDFISTLLRIPAGAVLAASVFGLDHTFVAALAAAAGGSLAAVSHGTKLSTRAAINTSPEPFSNVGASLGEDALVLGGLWLAWLHPVLFFIALVLVLIVMVWLARKSFHFVRGLLARMVRMFSGRPEPAATQPPHGATDVSYRDKPD
>NC_014153.1|WP_013124192.1|2892896_2893925_-|biotin-synthase-BioB
MTPKPSDVWTPERIEALLDLPLPELLWQAQQIHRAHFDPTDIQLSSLLSIKTGGCAEDCGYCPQSAHHDVGLKAGKLMDLDLVLANARAAKEAGAARFCMGAAWREPKDRDLDAVAEMVEGVKALGLETCMTLGMLRPAQAQRLADAGLDYYNHNLDTSPEFYGQIITTRTYQERLDTLQAVREAGMAVCCGGIVGMGETRRDRAGLLAELAGLDPHPESVPINALVRVAGTPLEHAPDLDPFEFVRTVAAARITMPTARVRLSAGRRELGDGIQALCFLAGANSIFYGDTLLVTGNSEVDADRALFARLGLHAGAQASPMPSATPKQKVIALQADSPVSRP
>NC_014153.1|WP_013124193.1|2893951_2894752_-|enoyl-CoA-hydratase
MSESPVLIDREGAVATVTLYRPEVRNAFDAATIAALHAVFVELGQEAEVRCVVLAAQGPAFCAGADLRYMQQLAAYTDAQNRDDALQLARMLRAVAECPKPVIARVQGDAFAGGFGLVAACDLAVAVQTARFCLSEVRLGLVPATIMPHVLRAIGPRAAQRYTLTAEVLSAATAQSIGLVHEVAVDAAALDAQVQRWCAALQNASPQALAAAKRLLAEVAHRPLGDALLADTAERIAVARASTDGREGIAAFLAKRKPNWIDPEAR
>NC_014153.1|WP_013124194.1|2894748_2895276_-|DNA-damage-inducible-protein-DinB
MTLQDHFRTLARYHVWATHRLLDEHVALLPEADYRRDCGLFFNSVHGTLNHLLVGEGLLWQRRFLEGVSPAGLKLDDEAEPDRARLAQRLKESARAWQPYVERLSEADFDRPFHYATSKGEPMSAPFAATLAHVFNHATHHRGQITVALTAMGHPSPVLDLIYMLRDEATASSKP
>NC_014153.1|WP_013124195.1|2895304_2895703_-|PIN-domain-nuclease
MILVDSSVWIDFFNGRATPRVANLALLLDDMAPVAVADLVLFEVLRGFRHERDYLAARKTLTALTVVEIGGEDNALQAAQHDRLLRAMGYTIRSAVDVLQAAYCIEHDYALLHNDADFDVMEDLRGLKVWRH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_014153_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014153_9

3057618-3057744

Orphan

Consensus_repeat	Method
TTTGCAGCGAAGACATCAATTATTGCACTACTTTTAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014153_9

>merge|NC_014153|9|3057618-3057744|CRISPRCasFinder
TTTGCAGCGAAGACATCAATTATTGCACTACTTTTAATCCCGAGTCAAGTAAAAGGTTTTATTCTTTTCTTTGCTTCGGTCGCTGTTTTTTTGCAGCGAAGACATCAATTATTGCACTATTTTTAAT

>NC_014153|9|9|3057618-3057744|CRISPRCasFinder
TTTGCAGCGAAGACATCAATTATTGCACTACTTTTAAT	CCCGAGTCAAGTAAAAGGTTTTATTCTTTTCTTTGCTTCGGTCGCTGTTTT
TTTGCAGCGAAGACATCAATTATTGCACTATTTTTAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_014153.1\|WP_013124323.1\|3048073_3049264_-\|elongation-factor-Tu	unknown	unknown	gnl\|CDD\|234596
NC_014153.1\|WP_013124327.1\|3060660_3061188_+\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|237573
NC_014153.1\|WP_013124320.1\|3045925_3046240_-\|50S-ribosomal-protein-L23	unknown	unknown	gnl\|CDD\|235586
NC_014153.1\|WP_013124333.1\|3066454_3067108_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|225418
NC_014153.1\|WP_155816343.1\|3065497_3066421_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|225797
NC_014153.1\|WP_081440427.1\|3059632_3060664_+\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NC_014153.1\|WP_013124324.1\|3049316_3051422_-\|elongation-factor-G	unknown	unknown	gnl\|CDD\|234569
NC_014153.1\|WP_013107280.1\|3047693_3048005_-\|30S-ribosomal-protein-S10	unknown	unknown	gnl\|CDD\|179076
NC_014153.1\|WP_013107284.1\|3052009_3052384_-\|30S-ribosomal-protein-S12	unknown	unknown	gnl\|CDD\|235355
NC_014153.1\|WP_013124325.1\|3057904_3058780_-\|D-amino-acid-aminotransferase	unknown	unknown	gnl\|CDD\|238799
NC_014153.1\|WP_013124331.1\|3064080_3065400_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_014153.1\|WP_013124319.1\|3045100_3045925_-\|50S-ribosomal-protein-L2	unknown	unknown	gnl\|CDD\|236488
NC_014153.1\|WP_013107283.1\|3051442_3051913_-\|30S-ribosomal-protein-S7	unknown	unknown	gnl\|CDD\|235398
NC_014153.1\|WP_013107287.1\|3058823_3059495_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_014153.1\|WP_013124328.1\|3061232_3062885_+\|apolipoprotein-N-acyltransferase	unknown	unknown	gnl\|CDD\|234721
NC_014153.1\|WP_013124322.1\|3046856_3047519_-\|50S-ribosomal-protein-L3	unknown	unknown	gnl\|CDD\|234564
NC_014153.1\|WP_013124330.1\|3063422_3064067_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NC_014153.1\|WP_013124329.1\|3062776_3063235_-\|DUF2784-domain-containing-protein	unknown	unknown	gnl\|CDD\|378502
NC_014153.1\|WP_013107275.1\|3044814_3045090_-\|30S-ribosomal-protein-S19	unknown	unknown	gnl\|CDD\|178985
NC_014153.1\|WP_013124321.1\|3046236_3046857_-\|50S-ribosomal-protein-L4	unknown	unknown	gnl\|CDD\|235404

Protein	Function_ID	Function_description	E-value
NC_014153.1\|WP_013124323.1\|3048073_3049264_-\|elongation-factor-Tu	gnl\|CDD\|234596	PRK00049, PRK00049, elongation factor Tu; Reviewed.	0
NC_014153.1\|WP_013124327.1\|3060660_3061188_+\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|237573	PRK13963, PRK13963, rRNA maturation RNase YbeY.	1.53879e-52
NC_014153.1\|WP_013124320.1\|3045925_3046240_-\|50S-ribosomal-protein-L23	gnl\|CDD\|235586	PRK05738, rplW, 50S ribosomal protein L23; Reviewed.	1.02226e-39
NC_014153.1\|WP_013124333.1\|3066454_3067108_-\|c-type-cytochrome	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	2.44833e-20
NC_014153.1\|WP_155816343.1\|3065497_3066421_-\|c-type-cytochrome	gnl\|CDD\|225797	COG3258, COG3258, Cytochrome c [Energy production and conversion].	4.91112e-82
NC_014153.1\|WP_081440427.1\|3059632_3060664_+\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	7.0904e-144
NC_014153.1\|WP_013124324.1\|3049316_3051422_-\|elongation-factor-G	gnl\|CDD\|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NC_014153.1\|WP_013107280.1\|3047693_3048005_-\|30S-ribosomal-protein-S10	gnl\|CDD\|179076	PRK00596, rpsJ, 30S ribosomal protein S10; Reviewed.	1.37102e-66
NC_014153.1\|WP_013107284.1\|3052009_3052384_-\|30S-ribosomal-protein-S12	gnl\|CDD\|235355	PRK05163, rpsL, 30S ribosomal protein S12; Validated.	7.96456e-87
NC_014153.1\|WP_013124325.1\|3057904_3058780_-\|D-amino-acid-aminotransferase	gnl\|CDD\|238799	cd01558, D-AAT_like, D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.	2.4614e-111
NC_014153.1\|WP_013124331.1\|3064080_3065400_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.39454e-28
NC_014153.1\|WP_013124319.1\|3045100_3045925_-\|50S-ribosomal-protein-L2	gnl\|CDD\|236488	PRK09374, rplB, 50S ribosomal protein L2; Validated.	0
NC_014153.1\|WP_013107283.1\|3051442_3051913_-\|30S-ribosomal-protein-S7	gnl\|CDD\|235398	PRK05302, PRK05302, 30S ribosomal protein S7; Validated.	3.42406e-103
NC_014153.1\|WP_013107287.1\|3058823_3059495_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.10722e-54
NC_014153.1\|WP_013124328.1\|3061232_3062885_+\|apolipoprotein-N-acyltransferase	gnl\|CDD\|234721	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed.	7.57215e-157
NC_014153.1\|WP_013124322.1\|3046856_3047519_-\|50S-ribosomal-protein-L3	gnl\|CDD\|234564	PRK00001, rplC, 50S ribosomal protein L3; Validated.	1.66769e-115
NC_014153.1\|WP_013124330.1\|3063422_3064067_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	3.38033e-37
NC_014153.1\|WP_013124329.1\|3062776_3063235_-\|DUF2784-domain-containing-protein	gnl\|CDD\|378502	pfam10861, DUF2784, Protein of Unknown function (DUF2784). This is a family of uncharacterized protein. The function is not known however it is conserved in Bacteria.	1.92096e-24
NC_014153.1\|WP_013107275.1\|3044814_3045090_-\|30S-ribosomal-protein-S19	gnl\|CDD\|178985	PRK00357, rpsS, 30S ribosomal protein S19; Reviewed.	2.4532e-62
NC_014153.1\|WP_013124321.1\|3046236_3046857_-\|50S-ribosomal-protein-L4	gnl\|CDD\|235404	PRK05319, rplD, 50S ribosomal protein L4; Provisional.	5.24948e-103

>NC_014153.1|WP_013107284.1|3052009_3052384_-|30S-ribosomal-protein-S12
MPTINQLVRSPRVSERIKSKSPAMENSPQRRGVCTRVYTTTPKKPNSALRKVAKIRLTNGFEVISYIGGEGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDLQAVKDRKQSRSKYGAKRPKK
>NC_014153.1|WP_013107283.1|3051442_3051913_-|30S-ribosomal-protein-S7
MPRRREVEKREILPDPKFGSVDVAKFMNVVMLSGKKAVAERIVYGAFDTIQEKSGKDPLEVFSAAMGNVRPMVEVKSRRVGGANYQVPVEVRPSRRMALAMRWIREAAKKRNEKSMQQRLANELLEAAEGRGSAMKKRDEVHRMAEANKAFSHFRF
>NC_014153.1|WP_013124324.1|3049316_3051422_-|elongation-factor-G
MARTTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMDRSLPDHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQMRTRLKANPVPIVVPIGAEENFKGVVDLLKMKAIIWDEASQGMKFNYEEIPAELVETCKEWREKMVEAAAESSEELMNQYLETGELSEAEIKQGLRARTIASEIQPMLCGTAFKNKGVQRMLDAVIDFMPSPIDIPPVAGHDDDEKEAVRRAADDEKFSALAFKLMTDPYVGQLTFIRVYSGVLSSGDTVYNPIKGKKERIGRLLQMHANNREEIKEVRAGDIAAAVGLKEVTTGETLCSPDAIITLEKMVFPEPVIAQAVEPKTKADQEKMGLALQRLAQEDPSFRVKTDEESGQTIISGMGELHLEIIVDRMKREFGVEANVGKPQVAYRETIRKTVENAEGKFVRQSGGKGQYGHVVLKVEPNEVGKGFEFVDAIKGGVVPREYIPAVQKGVEESLNSGVLAGYPVVDVKVTLHFGSYHDVDSSEQAFKIAASMGFKEGCRKANPVILEPMMAVEVETPEDYAGNVMGDLSSRRGMVQGMEDMVGGGKAIKAEVPLSEMFGYSTTLRSMSQGRATYTMEFKHYSEAPKNVADAIVSARASK
>NC_014153.1|WP_013124323.1|3048073_3049264_-|elongation-factor-Tu
MAKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLSAKFGGSAKKYDEIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVFLNKCDMVDDAELLELVEMEVRELLSKYDFPGDDTPIIKGSAKLALEGDKGELGEKAIFNLADALDSYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRIERGIIKVGEEIEIVGIRATQKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREDVERGQVLCKPGSVKPHTHFTAEIYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGAVELPKDKEMVMPGDNVSITVKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
>NC_014153.1|WP_013107280.1|3047693_3048005_-|30S-ribosomal-protein-S10
MQNQKIRIRLKAFDYKLIDQSAMEIVDTAKRTGAIVKGPVPLPTRLQRFDILRSPHVNKTSRDQLEIRTHLRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
>NC_014153.1|WP_013124322.1|3046856_3047519_-|50S-ribosomal-protein-L3
MSSHSMGLVTRKVGMTRVFTDDGASIAVTVLDASGNRVSQVRTQDVDGYSAVQVAYGSRKPSRLTKGQAGHLAKAGVEPAEILKEFDLPAEKAADYALGATVPASLFQVGQMVDAQGVSIGKGFAGSIKRHNFSSNRASHGNSVTTRAPGSIGMAQDPGRVFPGKRMAGQMGNETVTVQNLEVVRIDEARQLILVKGAVPGSRSGFVFLRPAVKSATGGQ
>NC_014153.1|WP_013124321.1|3046236_3046857_-|50S-ribosomal-protein-L4
MQLDFINAQGQPAEKFEVSPEVFGRDFNEDLVHQIVIAYQANARLGNRAQKDRAVVKHSTRKPWKQKGTGRARAGMTSSPLWRGGGKIFPNSPDENFTHKVNKKAYRAGMRSLFSQLAREGRLVVVDTFTVEAPKTKLVAEKCKAMGFDSVMIIADGADENLFLAARNLPNVLVVEPRYADPLSLLFYKKVVMTKGAVSQLQEMLS
>NC_014153.1|WP_013124320.1|3045925_3046240_-|50S-ribosomal-protein-L23
MTQAVLNPQRLMQVLSTPVISEKATMVAEKRNQVVFRVLRDATKPEIKAAVELLFKVDVESVQVANIKGKVKRTARGTGRRNHVKKAYVCLKAGQELNFAQEGI
>NC_014153.1|WP_013124319.1|3045100_3045925_-|50S-ribosomal-protein-L2
MPVVKVKPTSAGRRAVVKVSHPHLYKGEPERSLLEPQFQKAGRNNNGHITTRHRGGGHKHHYRVVDFRRDKDGIPAKVERIEYDPNRTAHIALVCYADGERRYIIAPRNLEVGATLMSGAEAPIRAGNTLPIRNIPVGSTIHCIEMQPGKGAQIARSAGASAVLLAREGIHAQVRMRSGEVRRIHIECRATLGEVSNEEHNLRQYGKAGAKRWQGIRPTVRGVAMNPVDHPHGGGEGKTGEGRVAVSPWGTPTKGYRTRNNKRTQSMIVSRRKK
>NC_014153.1|WP_013107275.1|3044814_3045090_-|30S-ribosomal-protein-S19
MARSLKKGPFCDQHLLKKVEAAVSTKDKRPVKTWSRRSTILPEFIGVTIAVHNGKQHVPVYVSDQMVGHKLGEFALTRTFKGHPADKKAKK
>NC_014153.1|WP_013124325.1|3057904_3058780_-|D-amino-acid-aminotransferase
MSFNPMSTDQSECYLNGVFQPLAQCQVSVLDRGFIFGDGVYEVIPVYGRRVFRADDHLARLARSLDAVGIKNPSQANDWLALVRELIARNAPDDQCIYIQVTRGVAKRDHAFPQGVEPTVFMMSFPFPHVPEQKRAQGVACITAPDLRWRNAHIKSISLLGNVLARQLSVESDATETVLIREGLLTEASASNVWLVRNGRLAAPLRDHDKLEGIRVGLLQELCGEIGIKLEFRPISEWELRCADEILLTSATKEVLSVATLDGKAVGQGKPGPVATALYSAYQEAKKSQSH
>NC_014153.1|WP_013107287.1|3058823_3059495_-|response-regulator-transcription-factor
MSTMQCALVVDDLPAVRAGFVELLRENYPGVRIFEAGRMADAMQILQREPVDLLLVDLGLPDASGLELIRTLTETRPQARSVVVTIFDDDDHLFPALQAGAFGYLLKDRPKIELRAQLRRIQDGEPPLSPSIARRMVQHFTHLHRTMSAPSSNLPQEEHIALTERESEVLQLVGKGYTLPEIAVQLGLSRHTVADYVKQIYRKLNISSRAEAALEAVRRGLVR
>NC_014153.1|WP_081440427.1|3059632_3060664_+|PhoH-family-protein
MQLRHTFSPPDNTRLAQLCGPLDENLRQIEVAFDVRLSRRADTVSIEGESAAARRALDLLQTLWGRADARFSLEDIQLELVQAAQGQRPKLTAADDEPVLYTRRESLHGRTPNQVQYIRNILQHDITFGIGPAGTGKTFLAVACAVDALERHAITRLVLTRPAVEAGERLGFLPGDLTQKIDPYLRPLYDALYDLLGMEKTQKLFERGAIEIAPLAFMRGRTLNQSFIILDEAQNTTPEQMKMFLTRIGFGSRAVITGDVSQVDLPRGTQSGLAQAQKVLADVRGIAFNSFTSQDVVRHPLVARIVDAYDAHDVALKGEPPSGASAGDLASATSSRRRPPRSA
>NC_014153.1|WP_013124327.1|3060660_3061188_+|rRNA-maturation-RNase-YbeY
MTRAARPTKPALRLSVQFADTTHRDQLPRALLLRWVRAALRVGLESLDALPQAGASPEAHQITLRFVAADEGRALNRAYRGKDYATNVLTFDYSHWPVQADIVLCCPVVAGEALAQHKPLGSHYAHLVIHGLLHAQGWDHQTELEAQEMERHEVTVLQRFGISDPYADGSEMPAG
>NC_014153.1|WP_013124328.1|3061232_3062885_+|apolipoprotein-N-acyltransferase
MSERPAKRDTQSATASAPPRGLQRQFTQPRFAPFVSIVLGVLLAQTFGRPQLGGWSIVILAAWISLLWADTQPRPKDRAKRGALLGFSLGLGWFTGGLWWLYISMAVYGGMAPPIAGGALLLFCAYLALYPTLAAALAAALAPAAGREPWKLARAIGAALVLAGGWTLAEWLRGTLFTGFPWLALGYAQVGNPLSGYAPVVGQYGVNFAAALAAALLALLSQVSLRGALVSLGLLVALFLGGLQLQQLRWTHAVGPALKVALLQGDVAQSEKFKPETLGPTLQLYGDWLSSLKANLIVTPETAVPVLPEDLDPGYLRQIERALREHHTAALLGIPLTRGADQYTNSVLGLGGAAPYRYDKSHLVPFGEFVPYGFHWFVKLMDMPLGSFARGGLDQPPFVVQGVKVAPNICYEDLFGAQMAQRFRNPAHAPNVFANLTNLGWFGNTIIIPQHLEIARMRSLEFQIPGIRATNTGATAIINAHGQVAAELPPYTVGVLTGSVQGHAGLTPFAWLASRYGDWPEVLLAAFALLLGWALTRLQRGGTHHHNARV
>NC_014153.1|WP_013124329.1|3062776_3063235_-|DUF2784-domain-containing-protein
MPALLDLQLAHLVLAVHLGVIVFNVAGLIVVPLGAWRRWRWVRGCVWRAAHLLSMAVVAAQAALGRACFLTLWQSALMQDAGQRGYTAGLIQTWIDHLIFWNLPLAVFTVIYLAVGAYTLALWWWVPPRCRRVRAQPSSKANAASSTSGQSP
>NC_014153.1|WP_013124330.1|3063422_3064067_+|TlpA-family-protein-disulfide-reductase
MQSLTVFLRRVGAAIVFCAACAPASWAAGFTFTPYPTAHKLPLSQVTFENAQGKHMTLADFKGKVVLLNIWATWCPPCVHEMPTLDKLQKLLGSKNFAVVPLSVDKGGIYTVKSFYDDNFISHLPIYVDPTTQVLDTLSILGTPTTILINKQGEEIARTMGPEDWDKPAVIAQIKHYMAAPAGSEAKPPQQARTVEIRDTRVATAATPTVAAPQ
>NC_014153.1|WP_013124331.1|3064080_3065400_+|MFS-transporter
MQTAAPEAFTQRPGDAFNHKRGAWAQISPAARRIILARTARSIGQGALVAAFTLYLHALNWNAPQIGAVLSGGLFIGAALTLWIGPLSDRLGRRQFLLGYELVLVVCAAVALLAATPWLLVPAALLGGFGRGANGAAGPFGPLEQSWLAHGTPPALRSQIFSLNSTLGMLGMALGAVLGAAPHWLSALMPTDWAYRSLFILPLLGSAIGFFLLLKAEDAPTATNPEARPLALATVPEDQDQADRQARHLRENALLWRLGLVNALNGLGIGMVAPLMAYWYLVRYGHGPASIGPAMAVSFVFAAFGAQIASRLAQRFGAVRAVVGMRTMGLIMLVLTPLSPVFSIAAGFYALRATANQGTMGVRQALTVSLTGADRRGLAATVNNVSIQIPRAIGPLIAGVLLHLGWLIAPFFVAATFQAAYLVLYQRFFKNIEPRDAAP
>NC_014153.1|WP_155816343.1|3065497_3066421_-|c-type-cytochrome
MTLALCALGLFAASAASALAADAPMAPPKSEINAAVGTGAKFTPPPESAIPDDDFGKMVKLGRDIMLDTPKYAKDYVGNTLSCVNCHTDAGRMAGSAPLWAAYVSYPAYRGKNKKVNTFEERLQGCFKFSQNGKAPPLGSKTLVALESYSYWLSKGLPVDEKVAGRGYPNLPEPQQAPDYVRGQKVYEAKCILCHAANGEGQYVNGETVFPPLWGPKSFNWGAGMGSYKNAAKFIYANMPYGMSYSLSPQEAWDVAYFMDAQERPQDPRWQGSVAATRAKFHDSKFSLYGTKVNGKLLGDIGAPKPR
>NC_014153.1|WP_013124333.1|3066454_3067108_-|c-type-cytochrome
MRQFIPMRRVLAVATLGALFWAAPASWAAAPPEAASCIACHGAGGMGNPAAGYPRLAGLPEQYLADQLRYFADGARNNAVMSGMAKPLSAAQVTALATYYSKLKPSGKPAPMPTGAAAAEGERLALRGDWEKGIPACIRCHGPGAVGVGENFPALVGQSAAYIEAQIKAWKDGSRSGDPLGLMHTVALRMTDAQTQAVAQWLAAQPLSPTKSASAKH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_014153_3	3.1\|533385\|29\|NC_014153\|CRISPRCasFinder	533385-533413	29	NC_014153.1	157107-157135	1	0.966
NC_014153_3	3.1\|533385\|29\|NC_014153\|CRISPRCasFinder	533385-533413	29	NC_014153.1	616853-616881	1	0.966
NC_014153_8	8.1\|2887200\|55\|NC_014153\|CRISPRCasFinder	2887200-2887254	55	NC_014153.1	270557-270611	1	0.982
NC_014153_3	3.1\|533385\|29\|NC_014153\|CRISPRCasFinder	533385-533413	29	NC_014153.1	1498661-1498689	2	0.931
NC_014153_8	8.1\|2887200\|55\|NC_014153\|CRISPRCasFinder	2887200-2887254	55	NC_014153.1	366530-366584	2	0.964
NC_014153_8	8.1\|2887200\|55\|NC_014153\|CRISPRCasFinder	2887200-2887254	55	NC_014153.1	2105801-2105855	2	0.964

1. spacer 3.1|533385|29|NC_014153|CRISPRCasFinder matches to position: 157107-157135, mismatch: 1, identity: 0.966

cctcccccacaagtgggggaggtgagaac	CRISPR spacer
cctcccccacaagtggaggaggtgagaac	Protospacer
****************.************

2. spacer 3.1|533385|29|NC_014153|CRISPRCasFinder matches to position: 616853-616881, mismatch: 1, identity: 0.966

cctcccccacaagtgggggaggtgagaac	CRISPR spacer
cctcccccacaagtggaggaggtgagaac	Protospacer
****************.************

3. spacer 8.1|2887200|55|NC_014153|CRISPRCasFinder matches to position: 270557-270611, mismatch: 1, identity: 0.982

tctcatcccccttggggggcctgacgcgaacgcggcaggtctgggggcgctctca	CRISPR spacer
tctcatccccctcggggggcctgacgcgaacgcggcaggtctgggggcgctctca	Protospacer
************.******************************************

4. spacer 3.1|533385|29|NC_014153|CRISPRCasFinder matches to position: 1498661-1498689, mismatch: 2, identity: 0.931

cctcccccacaagtgggggaggtgagaac	CRISPR spacer
cctcccccacaagtggaggaggttagaac	Protospacer
****************.****** *****

5. spacer 8.1|2887200|55|NC_014153|CRISPRCasFinder matches to position: 366530-366584, mismatch: 2, identity: 0.964

tctcatcccccttggggggcctgacgcgaacgcggcaggtctgggggcgctctca	CRISPR spacer
tctcatccccctcggggggcctgacgcgaacgcggcaggtctgggggcactctca	Protospacer
************.***********************************.******

6. spacer 8.1|2887200|55|NC_014153|CRISPRCasFinder matches to position: 2105801-2105855, mismatch: 2, identity: 0.964

tctcatcccccttggggggcctgacgcgaacgcggcaggtctgggggcgctctca	CRISPR spacer
tctcatcccccttggggggcctgacgcgaacgcggcaggtctggggggcctctca	Protospacer
***********************************************  ******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1626836 : 1690925

Acidithiobacillus_phage(21.43%)

transposase,holin,integrase

attL 1627323:1627341|attR 1692364:1692382

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013123163.1\|1626836_1628378_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	8.1e-92	39.9
1627323:1627341	attL	NA	NA	NA	NA
WP_155816257.1\|1628447_1628837_-	IS66 family insertion sequence element accessory protein TnpB	S5WJH4	Leptospira_phage	1.1e-05	33.3
WP_013123165.1\|1628793_1629162_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_013123167.1\|1629569_1629911_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_013122322.1\|1630938_1631964_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_041608618.1\|1632660_1633542_-	restriction endonuclease	NA	NA	NA	NA
WP_013123171.1\|1633580_1636253_-	type III restriction endonuclease subunit R	NA	NA	NA	NA
WP_013123172.1\|1636258_1637785_-	site-specific DNA-methyltransferase	A0A220NUF4	Escherichia_phage	6.6e-70	41.0
WP_013123173.1\|1637827_1638334_-	hypothetical protein	NA	NA	NA	NA
WP_013123174.1\|1638333_1639527_-	ATP-binding protein	NA	NA	NA	NA
WP_013123175.1\|1639928_1641275_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_013123176.1\|1641276_1641540_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013123178.1\|1644258_1645455_-\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	3.7e-84	44.3
WP_155816258.1\|1645676_1645898_-	hypothetical protein	NA	NA	NA	NA
WP_013123179.1\|1645903_1646179_-	hypothetical protein	NA	NA	NA	NA
WP_013123180.1\|1646196_1648599_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_013123181.1\|1648595_1648997_-	mobilization protein	NA	NA	NA	NA
WP_013123182.1\|1649526_1649748_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013123183.1\|1650272_1650824_+	hypothetical protein	NA	NA	NA	NA
WP_013123184.1\|1651405_1652938_+	hypothetical protein	NA	NA	NA	NA
WP_013123185.1\|1653517_1656328_+	class I SAM-dependent DNA methyltransferase	Q6NE04	Leptospira_phage	2.5e-123	33.9
WP_013123186.1\|1656399_1656612_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_013123187.1\|1656611_1657010_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_013123188.1\|1657010_1659089_+	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_013123189.1\|1659081_1660287_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_013123190.1\|1660333_1660654_+	transcriptional regulator	NA	NA	NA	NA
WP_013123191.1\|1660640_1660925_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013123192.1\|1662162_1662432_+	CopG family transcriptional regulator	NA	NA	NA	NA
WP_013123193.1\|1662418_1662787_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_013123194.1\|1663040_1663568_+	DUF4102 domain-containing protein	B7SYF8	Stenotrophomonas_phage	3.9e-30	43.8
WP_013123196.1\|1664758_1665496_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.7e-77	59.3
WP_013122263.1\|1668327_1669149_+	ATPase AAA	A0A2L1IVB6	Escherichia_phage	4.3e-31	35.1
WP_013121992.1\|1670434_1672132_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_041608402.1\|1672565_1673741_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_041608403.1\|1673791_1674499_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	9.1e-14	26.1
WP_013123199.1\|1674485_1675250_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	7.2e-17	28.1
WP_013123200.1\|1675236_1676271_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_013123201.1\|1676267_1677137_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_013123202.1\|1677385_1678060_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_013123203.1\|1678082_1679996_+	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	2.5e-119	38.3
WP_013123204.1\|1680006_1681617_+\|holin	choline dehydrogenase	A0A1V0S9J5	Catovirus	1.5e-51	29.7
WP_013123205.1\|1681631_1683947_+	arylsulfatase	NA	NA	NA	NA
WP_013123206.1\|1684011_1685370_+	MFS transporter	NA	NA	NA	NA
WP_013123207.1\|1685575_1686562_+	transporter	NA	NA	NA	NA
WP_013123208.1\|1686678_1688184_+	MFS transporter	NA	NA	NA	NA
WP_155816259.1\|1688216_1688456_+	hypothetical protein	NA	NA	NA	NA
WP_013123210.1\|1688593_1689331_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.4e-70	56.6
WP_013123211.1\|1689380_1690925_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	2.0e-159	56.3
1692364:1692382	attR	NA	NA	NA	NA

DBSCAN-SWA_2

2002991 : 2068291

Bacillus_phage(13.33%)

transposase,integrase,tRNA

attL 2049720:2049735|attR 2071668:2071683

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013123464.1\|2002991_2005832_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.5e-139	37.2
WP_013106244.1\|2006067_2006400_-	integration host factor subunit beta	A7KV42	Bacillus_phage	1.1e-09	33.3
WP_013123465.1\|2006547_2008251_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_041608418.1\|2008325_2010305_-	bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase	NA	NA	NA	NA
WP_013123467.1\|2010291_2011206_-	prephenate dehydrogenase/arogenate dehydrogenase family protein	NA	NA	NA	NA
WP_013123468.1\|2011210_2012341_-	histidinol-phosphate transaminase	A0A1X7BZP2	Faustovirus	1.1e-16	25.7
WP_013123469.1\|2012376_2013474_-	prephenate dehydratase	NA	NA	NA	NA
WP_013123470.1\|2013480_2014584_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.1e-85	46.5
WP_013123471.1\|2014590_2017197_-	DNA gyrase subunit A	A0A172JHV7	Bacillus_phage	3.7e-105	30.4
WP_013106252.1\|2017637_2018330_+	OmpA family protein	NA	NA	NA	NA
WP_013123472.1\|2018504_2019863_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_013123473.1\|2019999_2020872_+	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_013123474.1\|2020916_2023244_-	ribonuclease R	Q0GXV6	Lactococcus_phage	3.7e-64	33.4
WP_013123475.1\|2023795_2024818_+\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	1.4e-63	42.9
WP_155816255.1\|2025744_2026876_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.6e-52	40.7
WP_081440402.1\|2027101_2027353_-	hypothetical protein	NA	NA	NA	NA
WP_013123476.1\|2027488_2027962_+	AAA family ATPase	A0A2R3UAQ8	Siphoviridae_environmental_samples	2.1e-27	53.6
WP_013123477.1\|2028314_2028932_-	hypothetical protein	NA	NA	NA	NA
WP_013123478.1\|2028979_2029393_-	DUF2924 domain-containing protein	NA	NA	NA	NA
WP_013123480.1\|2029824_2030499_-	SOS response-associated peptidase	B7SYF4	Stenotrophomonas_phage	1.3e-33	39.3
WP_013123481.1\|2030701_2031469_+	translesion DNA synthesis-associated protein ImuA	NA	NA	NA	NA
WP_013123482.1\|2031425_2032802_+	DNA polymerase Y family protein	NA	NA	NA	NA
WP_013123483.1\|2032809_2035923_+	error-prone DNA polymerase	A0A1C9LWS4	Streptomyces_phage	6.4e-96	27.5
WP_013123484.1\|2036035_2036641_-	hypothetical protein	NA	NA	NA	NA
WP_013123485.1\|2036940_2038044_-	replication C family protein	NA	NA	NA	NA
WP_013123486.1\|2038040_2039030_-	AAA family ATPase	A0A0E3GMB2	Rhodoferax_phage	2.0e-11	27.5
WP_013104997.1\|2039022_2039229_-	hypothetical protein	NA	NA	NA	NA
WP_013123487.1\|2039534_2040197_+	DUF433 domain-containing protein	NA	NA	NA	NA
WP_013123488.1\|2040193_2040616_+	hypothetical protein	NA	NA	NA	NA
WP_041608660.1\|2041494_2041812_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013123490.1\|2041811_2043137_+	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_013123491.1\|2043429_2043726_-	hypothetical protein	NA	NA	NA	NA
WP_013123492.1\|2044033_2044363_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_013123493.1\|2044563_2044776_+	hypothetical protein	NA	NA	NA	NA
WP_013123494.1\|2045085_2046339_-	hypothetical protein	NA	NA	NA	NA
WP_041608661.1\|2047924_2048335_+	hypothetical protein	NA	NA	NA	NA
WP_013123497.1\|2048541_2049093_-	TMEM165/GDT1 family protein	NA	NA	NA	NA
WP_155816265.1\|2049134_2050363_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	3.9e-129	82.4
2049720:2049735	attL	NA	NA	NA	NA
WP_013123501.1\|2052917_2053493_+	hypothetical protein	NA	NA	NA	NA
WP_155816266.1\|2053721_2054225_+	hypothetical protein	NA	NA	NA	NA
WP_013123503.1\|2054785_2055445_+	hypothetical protein	NA	NA	NA	NA
WP_013123504.1\|2055458_2055911_+	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_155816267.1\|2055930_2057247_+	DUF3443 family protein	NA	NA	NA	NA
WP_155816255.1\|2058471_2059604_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.6e-52	40.7
WP_013123507.1\|2059726_2060356_+	hypothetical protein	NA	NA	NA	NA
WP_013123508.1\|2060454_2061096_+	hypothetical protein	NA	NA	NA	NA
WP_155816331.1\|2061515_2061767_-	hypothetical protein	NA	NA	NA	NA
WP_013123511.1\|2061760_2061967_-	DUF3563 domain-containing protein	NA	NA	NA	NA
WP_013123512.1\|2062265_2062895_+	hypothetical protein	NA	NA	NA	NA
WP_013123513.1\|2063395_2063671_-	hypothetical protein	NA	NA	NA	NA
WP_155816268.1\|2063759_2066513_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013123516.1\|2067085_2068291_+\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	9.2e-83	45.2
2071668:2071683	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3299965 : 3306948

Acinetobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_141130661.1\|3299965_3300511_-	transcription termination/antitermination protein NusG	G3MAW2	Bacillus_virus	1.1e-11	31.4
WP_013107511.1\|3300539_3300923_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_013124520.1\|3301191_3302382_-	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	2.6e-13	27.5
WP_041608782.1\|3302912_3303692_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	4.4e-54	50.2
WP_013124522.1\|3303781_3304828_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	2.7e-78	45.1
WP_013107514.1\|3304814_3305405_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	6.5e-66	59.5
WP_013124523.1\|3305448_3306948_-	anthranilate synthase component I	S4VT78	Pandoravirus	4.1e-40	32.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014153

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection