CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_014217	Starkeya novella DSM 506, complete sequence	2 crisprs	csa3,WYL,DEDDh	0	1	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_014217_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014217_1

307566-307649

Orphan

Consensus_repeat	Method
CCGCCGCCCAAGCCCGGCTGGGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014217_1

>merge|NC_014217|1|307566-307649|CRISPRCasFinder
CCGCCGCCCAAGCCCGGCTGGGGCAAGCCCGGCTGGGGTGGTCCCGGCTGGGGTGGACCTCCGCCGCCGAAGCCCGGCTGGGGC

>NC_014217|1|1|307566-307649|CRISPRCasFinder
CCGCCGCCCAAGCCCGGCTGGGGC	AAGCCCGGCTGGGGTGGTCCCGGCTGGGGTGGACCT
CCGCCGCCGAAGCCCGGCTGGGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014217.1\|WP_013165148.1\|304912_305935_+\|complex-I-NDUFA9-subunit-family-protein	unknown	unknown	gnl\|CDD\|187579
NC_014217.1\|WP_013165154.1\|310281_312687_+\|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234804
NC_014217.1\|WP_013165146.1\|301434_303363_+\|cytochrome-c	unknown	unknown	gnl\|CDD\|365823
NC_014217.1\|WP_013165140.1\|291016_292846_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl\|CDD\|225719
NC_014217.1\|WP_013165153.1\|309158_310262_+\|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|234780
NC_014217.1\|WP_013165152.1\|308536_308905_+\|50S-ribosomal-protein-L20	unknown	unknown	gnl\|CDD\|179959
NC_014217.1\|WP_013165151.1\|308304_308505_+\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
NC_014217.1\|WP_013165141.1\|292842_293562_+\|nucleotidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133044
NC_014217.1\|WP_013165157.1\|314940_315837_+\|LysR-family-transcriptional-regulator-ArgP	unknown	unknown	gnl\|CDD\|235144
NC_014217.1\|WP_013165158.1\|316017_316680_+\|sulfate-transporter-family-protein	unknown	unknown	gnl\|CDD\|237196
NC_014217.1\|WP_013165143.1\|296636_300071_+\|double-strand-break-repair-helicase-AddA	unknown	unknown	gnl\|CDD\|274298
NC_014217.1\|WP_013165145.1\|300626_301133_+\|DUF1993-domain-containing-protein	unknown	unknown	gnl\|CDD\|370447
NC_014217.1\|WP_013165156.1\|314242_314851_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NC_014217.1\|WP_013165155.1\|312818_314171_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|366721
NC_014217.1\|WP_013165160.1\|317550_318081_+\|DUF2244-domain-containing-protein	unknown	unknown	gnl\|CDD\|378350
NC_014217.1\|WP_013165144.1\|300153_300474_+\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
NC_014217.1\|WP_013165142.1\|293598_296640_+\|double-strand-break-repair-protein-AddB	unknown	unknown	gnl\|CDD\|274300
NC_014217.1\|WP_041782677.1\|316676_317402_-\|endonuclease-III	unknown	unknown	gnl\|CDD\|223255
NC_014217.1\|WP_013165149.1\|306098_306905_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712
NC_014217.1\|WP_041782672.1\|303613_304453_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359

Protein	Function_ID	Function_description	E-value
NC_014217.1\|WP_013165148.1\|304912_305935_+\|complex-I-NDUFA9-subunit-family-protein	gnl\|CDD\|187579	cd05271, NDUFA9_like_SDR_a, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs. This subgroup of extended SDR-like proteins are atypical SDRs. They have a glycine-rich NAD(P)-binding motif similar to the typical SDRs, GXXGXXG, and have the YXXXK active site motif (though not the other residues of the SDR tetrad). Members identified include NDUFA9 (mitochondrial) and putative nucleoside-diphosphate-sugar epimerase. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.40881e-108
NC_014217.1\|WP_013165154.1\|310281_312687_+\|phenylalanine--tRNA-ligase-subunit-beta	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NC_014217.1\|WP_013165146.1\|301434_303363_+\|cytochrome-c	gnl\|CDD\|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	2.24831e-10
NC_014217.1\|WP_013165140.1\|291016_292846_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl\|CDD\|225719	COG3178, COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only].	1.37839e-115
NC_014217.1\|WP_013165153.1\|309158_310262_+\|phenylalanine--tRNA-ligase-subunit-alpha	gnl\|CDD\|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NC_014217.1\|WP_013165152.1\|308536_308905_+\|50S-ribosomal-protein-L20	gnl\|CDD\|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	7.2471e-66
NC_014217.1\|WP_013165151.1\|308304_308505_+\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	4.22283e-19
NC_014217.1\|WP_013165141.1\|292842_293562_+\|nucleotidyltransferase-family-protein	gnl\|CDD\|133044	cd06422, NTP_transferase_like_1, NTP_transferase_like_1 is a member of the nucleotidyl transferase family. This is a subfamily of nucleotidyl transferases. Nucleotidyl transferases transfer nucleotides onto phosphosugars. The activated sugars are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. Other subfamilies of nucleotidyl transferases include Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase.	5.98733e-102
NC_014217.1\|WP_013165157.1\|314940_315837_+\|LysR-family-transcriptional-regulator-ArgP	gnl\|CDD\|235144	PRK03635, PRK03635, ArgP/LysG family DNA-binding transcriptional regulator.	4.26279e-157
NC_014217.1\|WP_013165158.1\|316017_316680_+\|sulfate-transporter-family-protein	gnl\|CDD\|237196	PRK12768, PRK12768, sulfate transporter family protein.	4.27027e-74
NC_014217.1\|WP_013165143.1\|296636_300071_+\|double-strand-break-repair-helicase-AddA	gnl\|CDD\|274298	TIGR02784, ATP-dependent_nuclease_subunit_A, double-strand break repair helicase AddA, alphaproteobacterial type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_014217.1\|WP_013165145.1\|300626_301133_+\|DUF1993-domain-containing-protein	gnl\|CDD\|370447	pfam09351, DUF1993, Domain of unknown function (DUF1993). This family of proteins are functionally uncharacterized.	7.95519e-92
NC_014217.1\|WP_013165156.1\|314242_314851_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	2.50439e-63
NC_014217.1\|WP_013165155.1\|312818_314171_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|366721	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	2.14161e-32
NC_014217.1\|WP_013165160.1\|317550_318081_+\|DUF2244-domain-containing-protein	gnl\|CDD\|378350	pfam10003, DUF2244, Integral membrane protein (DUF2244). This domain, found in various bacterial hypothetical and putative membrane proteins, has no known function.	9.78028e-49
NC_014217.1\|WP_013165144.1\|300153_300474_+\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	1.53511e-53
NC_014217.1\|WP_013165142.1\|293598_296640_+\|double-strand-break-repair-protein-AddB	gnl\|CDD\|274300	TIGR02786, conserved_hypothetical_protein, double-strand break repair protein AddB, alphaproteobacterial type. AddAB is a system well described in the Firmicutes as a replacement for RecBCD in many prokaryotes for the repair of double stranded break DNA damage. More recently, a distantly related gene pair conserved in many alphaproteobacteria was shown also to function in double-stranded break repair in Rhizobium etli. This family consists of AddB proteins of the alphaproteobacteial type. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_014217.1\|WP_041782677.1\|316676_317402_-\|endonuclease-III	gnl\|CDD\|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	8.81235e-104
NC_014217.1\|WP_013165149.1\|306098_306905_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	1.00343e-93
NC_014217.1\|WP_041782672.1\|303613_304453_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	7.26775e-15

>NC_014217.1|WP_013165149.1|306098_306905_-|undecaprenyl-diphosphate-phosphatase
MSFGTLLEAFLLGLLEGFTEFLPVSSTGHILLAGHFLGFESQGKVFEVVIQLGAILAIVVAYFQRFLHVLVTLPTSERSRNFVIGILIAFLPAAVIGAFAHGFIKNVLFETPALICIMLILGGGVLLWVDTLKLRPIHDDAMAFPKALALKIGFIQCLAMIPGVSRSGSTIVGGLLLGASKPAAAEFSFFLALPTMAGAFAYDLYKNRDALNADDATLIAVGFVAAFIAALAVVRGLIAFVSRHGYTPFGWWRIAVGGVGLVALALVG
>NC_014217.1|WP_013165148.1|304912_305935_+|complex-I-NDUFA9-subunit-family-protein
MVDVAAELPLESEAELEARAAPMERLVTIYGGSGFIGRHVVRALAKRGWRVRVAVRRPDLAGHLQPLGAVGQINPVQANLRYPASVLRAAEGAEVVINLVGVLHESGRQSFEAVHAFGAKQVALAAREVGARLIHGSAIGANAESTAFYGKSKAAGEAAAFEAVPEAVIMRPSIVFGPEDDFFNRFASMSRLSPVLPLIGGGETRFQPVFVGDVAEAYARAVDNLARPGTVYELGGPEILSFKQLMELMLAEIDRKRLLVPVPSAVAAFKARFLELLPNPLLTRDQVRMLGYDNVVSEAAKAEGRTLEGLGIKPTALGAILPSYLWRYRKAGQFTRPEAA
>NC_014217.1|WP_041782672.1|303613_304453_+|DMT-family-transporter
MLLLAVMWGLSIPVTKMGLETLPPLTLTALRFAVAVPLLFALLAGRWRLPWRAVPKVAALGFLAIGIGQVTQTLGVVGTSASVGTVITATIPLFIVVIAALRLRQPVTLLQTAGLIAAFAGIALVAFGDRDPAALAQTTASGAILMLLSAAAIAFYYVWSVEVADAYGTVTVVAWSTLCGFISLAPWAAWEASNTPFVIGVTAIGAAIYLGVVVTVAGLFLWLNMLRTVPARVAASVQFLQPVVGVMASAALFGDHLGLAFFVGVALVLTGLATTLANR
>NC_014217.1|WP_013165146.1|301434_303363_+|cytochrome-c
MSGARKRGIVFGLAAAFWGLGLAPAPAQTPAAPDDSALVARGEYLARAADCMPCHTGDKAKPFAGGLGLNTPFGTLYSVNITSDVATGIGSWSFDDFRRALHDGIRKDGAYLYPAMPFDAYTGITEDDLKALWAYVRRIPAVNAPNPENGLSFPFNIRLGMLAWRELFFQPAFFKPTPGKSDEWNRGAYLVEALGHCSDCHSPRNIMGAIKGKEAFTGAEVDGFYAPDIASGALGKTWRKDMLIQFLKTGSAPQKTVVFGPMAEVVHDSLSHLTDADLAAMATYLLESPPPLDAPAPQKASPLPADVYARASKLFIDNCAVCHQQQGTGLLGAIPSLAGNPAVTAAEPYNVIAATLHGLPSDGHYGTMPSFAGRLSDQQIADVVNYVRTAWGNQGTPNATPRMVAAWRETVKVPDYGTQAASAFDCAQVGGAPGAPGPDPKAVAALTAAIAGGNREVSSLVESYEAAAPNASPAQVVDALMAAYCPVVAAGAGEDYQKYARLKGFTLQAAADVSFRGTPDSLPDVPVVTAVVAGKSLVARQPESLAGPLACPAAGKIPADLVTAAAGLIGKPQLPVPGGAGGGYARELVTKNPKARPADIANALILSYCGLVAADKGIEPATQHAYVEDFGQQVIQTLQVQP
>NC_014217.1|WP_013165145.1|300626_301133_+|DUF1993-domain-containing-protein
MPLSIYDASIPVFERALRNLDAILTKAEEHAAANGIDLSELAAARLAPDMFPLTGQIQSASDSAKFAAARLTGTTGPSFADTETTFEELHARIAKTLDYLASVDRAGFEGAETREIVQKSRRGERHFVGQAYLLTFALPNFFFHVTTAYDILRHKGVPVGKSDYLGAF
>NC_014217.1|WP_013165144.1|300153_300474_+|thioredoxin
MGVEKVSDQSFESDVIKSDGPVLVDFWAEWCGPCRMVAPVLDEVAGELGDKLKIVKLNVDENPATASKYGIMSIPTLLLFKDGQLASRQVGAAPKAKMLQWINSAI
>NC_014217.1|WP_013165143.1|296636_300071_+|double-strand-break-repair-helicase-AddA
MSELTDLAPGPLRAATALQTTASDPLLSAWVSANAGSGKTHVLARRVIRLLMRGVPPGRILCLTYTKAAAANMANRVLDELRRWATLDDETLDKEIVRTDGGRPDALRRAHARRLFAQALETPGGLKIQTIHAFCGALLHAFPFEAGVPAGFGELEEAARLELLARVRADVVLEAAGRPESALGQALGLIVGTTSDDGIDEIIGAMVADPAALEASDDDLAAAVGLDRPIASRDIEHRIIAEALIARGAWLGLGQALIEEGGNCARRGRSLLEAAAAPDEGTADTYARVFLKEDGEPYGDSQFGAAPIRAKYPLLLAERDRLAPLAQLLSAARALERSRGVLILGREAARRYERAKAARGVLDFSDLVDAARRLLASGASAWVHYKLDQGIDHVLLDEAQDTSPEQWEVIRPLVAEFFAGEGARAEARYGAASLPRTLFVVGDEKQSIFSFQGADPRRFDTVRRELMRLTGGVGFEHIELRHSFRSAPGILAAVDTVFHAETAYQGLSALAEPPVHEAIHAALPSLVELWEPEAPSEKVDIDAWQRPLDAPAADDPKGRLARKIAGHIAARIREGFPVTGRHGTRPARPGDFLILVRRRDSLFEAIIRELKEARVAVAGADRLTVAQHIAVMDLMALGDALLARDDELALACALKSPLFGLDDSDLMKLAPERAGLLEDALFARAGENPHWRAAAERLRRLRPEARRLRPFDFYARVLGRERGRAAMIARLGPEAADALDEMLALARSYENVEAPSLAGFLAFLRRGGAEAKRDMEAGRDEVRVMTVHGAKGLEAPYVILADTTSGPMTRRAAGLLRVELPDGRRAALHAPSKKGDTPAMARARAQGDAAQQDEYRRLLYVALTRAESALVLAGADGGRKRPADCWYDLVRGALEPEAVEQPAAGFAGTVRRWRSAVHEEIIAAPAVAAIAAAPDEAERALARALSRPIEEPAARAALRPSASSLLSAAPEGPEALALHRGELLHRLMAALASLPPEERAAPGRRLLAAAGDFEEAAREELLTEALGVLAVPGLADLFGPGSLAEVPLVGELEDGTPVSGRIDRLAVLGDRILIADFKTDRRVPREASSLPPAHVRQVALYARLLRRLYPGRPIEARLVYTAGPLAHALGADVLERIVESVTSQ
>NC_014217.1|WP_013165142.1|293598_296640_+|double-strand-break-repair-protein-AddB
MSRPDPNLLTIPASAPFLAVLADALLDGRLVEGFAPRHDPFALASATVFLPTRRAGRLLAEALRARMESGVTLLPRIVPLGDVDEDSLAFAESFTDPPRAVPGMTRRLALASLVRRWRRLLAGDDGRVAVAAGPGAEFALADALAHLIDEMAAQQVPWEKLDTLVPGQHDLYWDMALDFLKIAREFWPALLDELGAVDASVRRDRLIAAEAERLRAAPAGPVIAAGSTGSMPATARLLAAVAHLTDGCVVLPGLDTDLDARSWDHLTDDEAPAPSHPQYGLALLLKAHMRVGRDAVRSLAPPAPHGRERLLSEALRPVASTEAWASLAERLGAAEIDAALAEVSVIEADDAREEALAIAVALREALEEPGRSAALVTPDRDLARRVAAELLRFEVAIDDSAGEPLSESAPGRFARLVADACDAELAPVPLSALLRHPLARFGLERGALDQAADALELMVLRGPRPEAGADGLVRAVAGFSPGLHHSSDPRAAIDTDRQALAAGLAERIARAFGPLLALGAGEHPFATLLEAHRAAVAAAWSAEDGGAAEDAIALAELSKTFEAMAEGASEAPVMRLADYAAALPLLLADRPVRPPLLPGARLRILGPLEARLVSVDRMVLAGLVEGTWPSAVRTDPWLSRPMRAALGLEAPERRIGLSAHDFAQGCGAPELILSHPRKLGGAPTVPSRFLQRLEAVSGEARWKMAKLRGDRFRRLAALIEEAPAASRIARPEPAPPVELRPKRLSVTEIETWLRDPYTIYARHVLRLRPLDMLDEAPGAAERGSAIHDALGAFAQAFPEALPAEPEAGLLAFGREAFRELEAFPAEYALWWARFERLVPRYIGWERARRADTRRVFAELGGRMALAGGRFALTGRADRIEQLREGGLAIIDFKTGAVPTAKQTAAHYSPQLPLEAAMAAAGGFRDLPAEGAAALTYVRLGTSELKEVGAVDRDETAFGLAASTLERLEQLIATFEDPSRGYASLARPMFRGRFGDYDHLARVKEWSTGGEGEE
>NC_014217.1|WP_013165141.1|292842_293562_+|nucleotidyltransferase-family-protein
MTAIKTAMVLAAGLGQRMRPLTDHMPKPMVAVNGRPLIDHVLDRLAEAGVEKAVVNLHWHADVLERHLLGRTRPRIVLSDERGALLETGGGIRKALPELGPDPFFVINADTIWIEGIRPNLAALAEGFDPEAMDIALLVAPIATSIGYDGHGDFLMDGEGRLTPRPERILAPFVYAGAAVVAPRIFAGTPQGPFSLSRLFRQAAEAGRLHGERMEGVWMHVGTPEAVALAEEAIERSKD
>NC_014217.1|WP_013165140.1|291016_292846_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MIDGRTTGAVPTMPVAHWDVVLPDEVATGRLAMDLAAMLRPGDLVALDGDLGAGKTTLARALIRELAGDPELEVPSPTFTLMQTYDLPRHRVVHADLYRLSDASELDELGWQEQTDGAVTLVEWPERAEGAVLKTDRLEVHISMPQDRPETARRVRLLGYGRLAGALYRMRAIRSLIDSTGFGPARRRHLQGDASTRSYERLVGAKRNAILMNAPRRPDGPPVRAGRSYSAVAHLAEDVKPFVAMARGLRARGFSAPAIYGGDLDAGLLVIEDLGEEGVLAGTPPAPVPERYEASVDVLAALHALDLPATLAVASGIDHQIPPYDLEALTIEAELLLDWYLPHCGVALPADARQSFRQLWAAALAPSLAQKPVWTLRDFHSPNLMWLPQREGIAKVGLLDFQDAVMGPPAYDVVSLAQDARVDVPEALELHLLGRYVKARREADADFDMRGFAASYAVMGAQRATKILGIFARLNHRDRKPGYLRHMPRIWNYLQRCLAFTDLEALAGWYKDHVPPPRLHGRPEGAVGMPAPAPVPAAPLAPPRPAEAAPKAPPAAPPAEAPPPTEAAAVTETPSAPATVAEAPAAETPPDAVPSEAASTQTPNDPATT
>NC_014217.1|WP_013165151.1|308304_308505_+|50S-ribosomal-protein-L35
MPKMKTKSGAKKRFKLSGTGKVVMAQAGKRHGMIKRTNKQIRDQRGTTVMSERDAFNVRKFYLPNG
>NC_014217.1|WP_013165152.1|308536_308905_+|50S-ribosomal-protein-L20
MARVKRGVTSHAKHKKVLKAAKGYFGRRKNTIRVAKQAVEKAQQYAYRDRKVKKRNFRALWIQRINAATRELGFTYGRFIDGLGKAGIEVDRKVLSDIAIHEPAAFAALVEQAKAALEKQAA
>NC_014217.1|WP_013165153.1|309158_310262_+|phenylalanine--tRNA-ligase-subunit-alpha
MSVAAALPDLDALERELSSAITAAADEAGLEAVRVSALGKKGSVSELLKSLGGMSPEERKTAGPAINGLRDRLNEALGARRTELKAAALTKRLETERVDVTLPVRETPAELGRVHPISQVIDELTAIFADMGFSVAEGPDIEDDFHNFTALNFPEGHPAREMHDTFYLPTKEDGSRLVLRTHTSPVQVRTMLSKKPPIRVICPGRTYRSDSDQTHTPMFHQVEGLVIDKGSNLGHLKWILEEFCKAFFEVDNVKMRFRPSFFPFTEPSMEVDIQCDRSRPGEIRFGEGSDWLEILGCGMVHPNVLKNCGLDPDEYQGFAWGMGIDRIAMLKYGMPDLRAFFEADVRWLSHYGFRPLDFPTLAGGLSN
>NC_014217.1|WP_013165154.1|310281_312687_+|phenylalanine--tRNA-ligase-subunit-beta
MKFTLSWLREHLSGDYSLDDVTGTLNRIGFEVEGVEDKAAKLKGFSIAYVVSAVQHPNADKLRVCMVDTGQGEPVQVVCGAPNARTGMKSVFSPPGTYIPGKDITLGIGTIRGVESRGMLCSAAELELSEDHDGIIDLPADAPVGATYVDWAGLGDPVVEIAVTPNRADGLGIHGIARDLAAAGVGTLIEKPIEAVKGAYPCPVSVIIAEGAPCPAFALRLVRGVKNGPSPDWLQAKLRAIGLRPINTLVDITNFLTFDQNRPLHVFDAAKVHGNLVVRRAKEGESLPALDGKTYALDESMCVIADDRAVESLAGVMGGEESGCDETTVDVLVESALWEPINIAQTGRKLGLNSDARFRFERGIDPAFTLPGLEMATKLILDLCGGEASEVVLAGAIPDTTRVIEFPLSLTEKLTGLVASDSEQVETLGKLGFKVEGTSGTARVTPPSWRGDIEGKADLVEEVVRIAGLDRVPSIPFPRDETARKPVLTTLQLRTRKAKRALAARGLVEAVTWSFVAKEQAELFGGGAPELALANPIASDLSDMRPSLLPGLIGSAQANADRGHGDSALFEVGQVFKGDRPQDQFIAATGIRRATARPMGAGRHWSAKAGAVDAFDAKADALAVLAAAGAPVANLQISTDAPAWFHPGRSGTFRLGPNVIGHFGELHPSVLEALDADGPLVGFEVLIDRIPEPKAKATRVKPLLELAAFQPVERDFAFVVPRSVAAGDMVKAAAGVDRKLITAVNVFDLYEGAGIDEDKKSVALSVTLQPREKTLTDAEIEAVAGKIVAEVAKKTGAMLRG
>NC_014217.1|WP_013165155.1|312818_314171_-|FAD-dependent-oxidoreductase
MNRSPSRPGALSRRRFLAATSAALLPMPALAQAQYAGDVDVAIVGGGAAGIAAARKIAEAGRNYVLLEAGSALGGRARTVSAFGQDIDLGASGFARTDSTLAAAAQAMGSEITPLPSGRRLFLDGREAHESAYDAFSVALGKARRDMLAVADTNKDPAAATVIGPVDGWAATSAQLIGPLSAGRALASLSTLDLVQREAPPDDATSVKGIGALIETLGSRLNVQTGAAVSVITNAGRFHTLTLRGQRAPIRARAIIVAVPAPVIAAGALRFNPVLPPRLAAAFRGVPAGFLEQVVFRLPRNPLGLQPNETVLARAGTAPPALLRGRINGGDVHVLTFGDAQAREIAEKGEAAALNLVRTYLATAFELDADAVSEVVCSRWGADPLFRGALVAASPGQGAQRRLFADTVQNRIFLAGDYVPTRGWGTLAAAWSSGEAAAARALRLVGDGPA
>NC_014217.1|WP_013165156.1|314242_314851_-|amino-acid-transporter
MPLSAYIAGLASGLSLIVAIGAQNAFVLQRGLRGEHVFAVCLACALSDAVLIAAGVAGLQQMLAMAPWLDAALRYAGAAFLVWYGARSLRSALRSQEALVVGAGGAAALGPTLAATLALTWLNPHVYLDTMVLLGTLSTRHPGAEAFFAFGAITGSFAFFFGLGYGAAWLRPLFARPSSWRVLEGVIAAVMWSIALGLLMDR
>NC_014217.1|WP_013165157.1|314940_315837_+|LysR-family-transcriptional-regulator-ArgP
MLDYSALRAVAAVVQAGSFEKAARTLNVTPSAVSQRVKQLEERLGTVLIARGTPCTATEIGAKLCRHMEHVGMLEGELLAGLPALADASPRQRVTVHIAVNADSLGTWFVEAIAAFARRSDYLVGLVVDDQDHTAEWLKAGRVVAAVTSLEKPIQGCRRLSLGALRYHATASPDYRARHFPDGVTPAAIANAPALTFDQKDQLQSRWIRQALGADIAHPTHWLPSPQSFIEATLAGMGWGMNPFRSVRDHLAAGRLVELIPDTPVDTPLFWQVNRLVAERLADLTREVTAVARRELAG
>NC_014217.1|WP_013165158.1|316017_316680_+|sulfate-transporter-family-protein
MLRDAFAAFAETFSPDYRRVLLRSVGFAVGLLVALGIGAHYALTYFVALDLRWAEITLDIVAAFGIFIAAIFLVPPVTSLIAGLFLDDVAAQVERGFPGEPEGQPLPIGRSLFLTVKFFGVMLAVNLVALLLLLVPGVNLVVFYVANGYLLGREYFQLAAMRYRDEDEVALLRRHHAGAIFLAGLIIAAVVSVPILNLVTPVFATIFMVRLHKRLSRREY
>NC_014217.1|WP_041782677.1|316676_317402_-|endonuclease-III
MLEEQAATRPGRRRAVANAAAAAIGGAFKPWTKKEVETAFSRFEEANPHPEGELNYHDPFTLLVAVVLSAQATDAGVNKATKTLFEEAPTPARMVALGEEGVARHIRTLGLYRGKAKNVVELSRLLIAEHDGKVPPDRAALEALPGVGRKTANVVLNIAFHMPTIAVDTHLFRVANRTGLAPGKTPLEVELGLERVIPDRFKLHAHHWLILHGRYICKALKPECPRCLIADLCRWPEKTPA
>NC_014217.1|WP_013165160.1|317550_318081_+|DUF2244-domain-containing-protein
MNAASTNQALGPTIDDEPTLFAARYQPYRSLGQHGFLVVMIIVAGISFVCGTAFLLMGAWPVFGMFGLDALAIYWAFRLNFRQARACEEIVVTPSLIRLRHVAADGTVYEEELNPLWTRLHRELHEDYGLQRLTLEMRGRPYVIGGFLHTAQREELAEQLSRALAEARRGVVRSTF

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Crispr_ID: NC_014217_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014217_2

2398357-2398454

Orphan

Consensus_repeat	Method
CAGCAGCAGGCGGGCGAAGCCCAGCGCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014217_2

>merge|NC_014217|2|2398357-2398454|CRISPRCasFinder
CAGCAGCAGGCGGGCGAAGCCCAGCGCCGGGCGGCCGAGCAGCAGCGCGCCCAGCAGGAACGGGCTCGCCAGCAGCAGGCGGGCGAGGCCCAGCGCCG

>NC_014217|2|2|2398357-2398454|CRISPRCasFinder
CAGCAGCAGGCGGGCGAAGCCCAGCGCCG	GGCGGCCGAGCAGCAGCGCGCCCAGCAGGAACGGGCTCGC
CAGCAGCAGGCGGGCGAGGCCCAGCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014217.1\|WP_013167086.1\|2401325_2402897_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|129794
NC_014217.1\|WP_013167077.1\|2390030_2391530_-\|tripartite-tricarboxylate-transporter-permease	unknown	unknown	gnl\|CDD\|225870
NC_014217.1\|WP_013167083.1\|2396106_2396490_-\|DUF930-domain-containing-protein	unknown	unknown	gnl\|CDD\|368726
NC_014217.1\|WP_013167078.1\|2391545_2392028_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815
NC_014217.1\|WP_013167092.1\|2409661_2410405_+\|DUF3750-domain-containing-protein	unknown	unknown	gnl\|CDD\|378882
NC_014217.1\|WP_013167075.1\|2387436_2388681_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_014217.1\|WP_013167081.1\|2394748_2395333_+\|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl\|CDD\|235552
NC_014217.1\|WP_013167076.1\|2388962_2389763_+\|sulfotransferase	unknown	unknown	gnl\|CDD\|379204
NC_014217.1\|WP_013167093.1\|2410528_2411347_+\|lytic-murein-transglycosylase	unknown	unknown	gnl\|CDD\|372592
NC_014217.1\|WP_144296078.1\|2402908_2404111_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|224482
NC_014217.1\|WP_013167088.1\|2404271_2404928_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379522
NC_014217.1\|WP_013167079.1\|2392114_2393101_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270294
NC_014217.1\|WP_041783246.1\|2387138_2387351_-\|hypothetical-protein	unknown	unknown	unknown
NC_014217.1\|WP_013167090.1\|2406645_2408022_-\|malonyl-CoA-decarboxylase	unknown	unknown	gnl\|CDD\|368376
NC_014217.1\|WP_013167094.1\|2411548_2411842_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|225383
NC_014217.1\|WP_013167091.1\|2408115_2409456_-\|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl\|CDD\|234815
NC_014217.1\|WP_013167080.1\|2393317_2394742_+\|aminodeoxychorismate-synthase-component-I	unknown	unknown	gnl\|CDD\|223225
NC_014217.1\|WP_013167082.1\|2395329_2396100_+\|aminotransferase-class-IV	unknown	unknown	gnl\|CDD\|238800
NC_014217.1\|WP_013167085.1\|2399233_2400787_-\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|234864
NC_014217.1\|WP_013167089.1\|2405022_2406240_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225139

Protein	Function_ID	Function_description	E-value
NC_014217.1\|WP_013167077.1\|2390030_2391530_-\|tripartite-tricarboxylate-transporter-permease	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_014217.1\|WP_013167083.1\|2396106_2396490_-\|DUF930-domain-containing-protein	gnl\|CDD\|368726	pfam06059, DUF930, Domain of Unknown Function (DUF930). Family of bacterial proteins with undetermined function. All bacteria in this family are from the Rhizobiales order.	2.08484e-47
NC_014217.1\|WP_013167094.1\|2411548_2411842_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|225383	COG2827, COG2827, Predicted endonuclease containing a URI domain [DNA replication, recombination, and repair].	1.43203e-27
NC_014217.1\|WP_013167078.1\|2391545_2392028_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	7.49429e-06
NC_014217.1\|WP_013167092.1\|2409661_2410405_+\|DUF3750-domain-containing-protein	gnl\|CDD\|378882	pfam12570, DUF3750, Protein of unknown function (DUF3750). This family of proteins is found in bacteria. Proteins in this family are typically between 175 and 265 amino acids in length.	2.72383e-65
NC_014217.1\|WP_013167075.1\|2387436_2388681_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.39834e-59
NC_014217.1\|WP_013167081.1\|2394748_2395333_+\|aminodeoxychorismate/anthranilate-synthase-component-II	gnl\|CDD\|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	1.82999e-119
NC_014217.1\|WP_013167076.1\|2388962_2389763_+\|sulfotransferase	gnl\|CDD\|379204	pfam13469, Sulfotransfer_3, Sulfotransferase family.	8.81589e-25
NC_014217.1\|WP_013167093.1\|2410528_2411347_+\|lytic-murein-transglycosylase	gnl\|CDD\|372592	pfam13406, SLT_2, Transglycosylase SLT domain. This family is related to the SLT domain pfam01464.	7.14489e-107
NC_014217.1\|WP_144296078.1\|2402908_2404111_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	4.79027e-109
NC_014217.1\|WP_013167088.1\|2404271_2404928_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379522	pfam14246, TetR_C_7, AefR-like transcriptional repressor, C-terminal region. This family comprises the C-terminal domain of transcriptional regulators of the TetR family. It includes the AefR transcriptional regulator from P. syringae. It is found in association with pfam00440.	4.50498e-37
NC_014217.1\|WP_013167086.1\|2401325_2402897_-\|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.40525e-132
NC_014217.1\|WP_013167090.1\|2406645_2408022_-\|malonyl-CoA-decarboxylase	gnl\|CDD\|368376	pfam05292, MCD, Malonyl-CoA decarboxylase C-terminal domain. This family consists of several eukaryotic malonyl-CoA decarboxylase (MLYCD) proteins. Malonyl-CoA, in addition to being an intermediate in the de novo synthesis of fatty acids, is an inhibitor of carnitine palmitoyltransferase I, the enzyme that regulates the transfer of long-chain fatty acyl-CoA into mitochondria, where they are oxidized. After exercise, malonyl-CoA decarboxylase participates with acetyl-CoA carboxylase in regulating the concentration of malonyl-CoA in liver and adipose tissue, as well as in muscle. Malonyl-CoA decarboxylase is regulated by AMP-activated protein kinase (AMPK).	5.96423e-153
NC_014217.1\|WP_013167079.1\|2392114_2393101_-\|hypothetical-protein	gnl\|CDD\|270294	cd13576, PBP2_BugD_Asp, Aspartic acid transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	3.98264e-142
NC_014217.1\|WP_013167091.1\|2408115_2409456_-\|Nramp-family-divalent-metal-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	0
NC_014217.1\|WP_013167080.1\|2393317_2394742_+\|aminodeoxychorismate-synthase-component-I	gnl\|CDD\|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	1.66442e-152
NC_014217.1\|WP_013167082.1\|2395329_2396100_+\|aminotransferase-class-IV	gnl\|CDD\|238800	cd01559, ADCL_like, ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.	3.63974e-62
NC_014217.1\|WP_013167085.1\|2399233_2400787_-\|2-isopropylmalate-synthase	gnl\|CDD\|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NC_014217.1\|WP_013167089.1\|2405022_2406240_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	1.69534e-114

>NC_014217.1|WP_013167083.1|2396106_2396490_-|DUF930-domain-containing-protein
MIRPSRMLSERALADPRSRAARRALATLAGEERIAQLCDLEAMEQIHAWQPGYQPDRLVDYARADTRLRETTFTATGGAFRSHRTWYEVSFHCELDASLAKVVSFAFKVGEPIPREEWSALSLPARH
>NC_014217.1|WP_013167082.1|2395329_2396100_+|aminotransferase-class-IV
MSQTVSVEDRGFTLGDGVFDTALARDGAVFARARHVDRLLLAAHRIGIAVSRDAIETAIDAALTMEPAIIRTTVTRGTAARGLWPASAGAPTVVVTTAPWSPALVGQPARLITATGRRNEFSPTANLKTLGYLDHILAAREAAEAGADDALILNTRGRVACSTIANVFALIAGRLITPSLSEGCLPGIMRALVIEAAPSLGFAVEERPLAPQALAGADAVFLTNSVRFLRPVTALDGMPLAQGDLAALQAALLARA
>NC_014217.1|WP_013167081.1|2394748_2395333_+|aminodeoxychorismate/anthranilate-synthase-component-II
MILLIDNYDSFVFNVARYLAELGEKVEVARNDALDIAEIEARRPEALIISPGPCSPNEAGVSLEAVRALSGRLPILGICLGHQCIGQAFGGRVVRAKEPMHGRASQVRHVGSDVFEGLPSPFPAGRYHSLAVELDEGSPLVATAWAEDGEIMGLAHRTHPTYGVQFHPESVLTGHGYDLLANFLKLARARETAA
>NC_014217.1|WP_013167080.1|2393317_2394742_+|aminodeoxychorismate-synthase-component-I
MIQEPPPLVVEIAWQEPWQAARRLGWREGARVPGLTFLDSAMRHPLLGRWSYVMAEPFGRFRVEAGVARWNGERERDAPLEALRARLRTYAQPRLPGDAGFQAGAAGYIAYEAGRLFDRFPTMAPEPGEGPEIDLGFYDLVVALDVVAERAFVISTGWPETDPSRRARRARERLTEATARLAAPEPALGPPVTAGAWRSNFDAERYRAAVARVIEYIRAGDIFQANFTQRFQAEVGQPGEILDPFALYDQLRRANPATFAALIVNEDRVIASSSPERFVKVEGGEVETRPIKGTVPRSVEPTLDAFRGRELTASEKDRAENVMIVDLLRNDLSRVCRPGTVKVPRLCGLETYANVHHLVSVVTGTLKEGADGLDLMAASFPGGSITGAPKIRAMEIIHELEGRPRGVYCGSIGYIGFDGTIDLNIAIRTVTVEDGVASFGVGGGITTLSDPAAEHEESLTKAERLFRAFKKPED
>NC_014217.1|WP_013167079.1|2392114_2393101_-|hypothetical-protein
MIKFKAAAAAIAALALAAVPFAGAKAQDFPNRPVTMVVPFAAGGPTDTVARLIAESMSRSLGQQVVVENVGGAGGTRGAGQVAKATPDGYTVLLHHIGQATSATLYRKLPYNVLTDFEEVGLVTDVPMTMIGKSTLEPKTAAELIAYVKDKKDGVIYGNAGVGSASHLCGMLFMSAIGTQMTTVPYQGTGPAMNDLVGGQIDLMCDQTTNTTGQIKAGKVKAYGVTTKERVKSLADIPTLQESGLPGFEVAVWHGMYAPKGTSPEVIKKLNAALVQALQDPKVISRFADLGTEPVALERATPEVHTKFLEAEVAKWKPVIEQAGVFAD
>NC_014217.1|WP_013167078.1|2391545_2392028_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MTRLVKSPKDVATGLLLIALAAFFAWQALDLPMGRAIRMGPGYFPMILAGILALLGLVIVASGIALPMGDDESPIDIARWPWRALALVTLAVVIFGIGIRPLGLGPSMGIAVFLSALASQKFHFLTGLVSALVMVAFSWAVFIKGLGLPLPMLGPWLGGY
>NC_014217.1|WP_013167077.1|2390030_2391530_-|tripartite-tricarboxylate-transporter-permease
MEIFDNLALGFSVAVTFQNIFYCFIGVLLGTLIGVLPGLGPVPTIAMLLPITFGLPPVSALIMLAGIYYGAQYGGSTTAILINLPGESSSVVTAIDGYQMARKGRAGAALATAALGSFFAGTVATFLLAVFAPPLADLALKFGPPEYFALMVLGLVASVALASGSVFKALAMVVLGILLGLSGQDVYTGTPRFTFDMLELADGIEFVALAMGVFGIGEIVRNLEDEHERTVMVRKVGGLLLSKDDIKRIVGPILRGTFLGSFLGILPGGGAVLSSFAAYSIEKRISKRPQEFGKGAIEAVAAPESANNAGAQTSFIPMLTLGIPSNPVMALMIGALIIQGIVPGPNVVNEQPNLFWGIVVSMWLGNFMLVVLNLPLIGIWVRLLTVPYHILFPLIVGFCCIGVYSVNNNAIDVFAMALFGIVGYVLVKLDCEPAPLLLGFIIGPMLEEYLRRAMLISRGDPTVFFTRPISATMLLLAIVALVVVLMPSVRKKREEAFKE
>NC_014217.1|WP_013167076.1|2388962_2389763_+|sulfotransferase
MGVRTFLRLKGPMFWQYPSGAVFICGCGHSGTTLLANMFSAHPQVFIPLRETSAFHRPTDKDAKRHRDALVMDFRRSQKTYLVEKTPRHILHLDRIRALMPAPKFILMVRDGRDVAASFLKRYGSPESGIERWLEAGEIIRSQDGRRDVILTRYEDLISDPRRELDRICAFSGIPFDEAMLRYHEMEHFWFGETEVRMGSGEEGDGHRALRNWQVNQPIFDGRRTWVGKLAPEALTAFTEGRGRELMSAFGYEVDLTPCDTGQDRT
>NC_014217.1|WP_013167075.1|2387436_2388681_-|GGDEF-domain-containing-protein
MFQWIDAIETPLAVIDVPSLHIVAANPSARALLRGGRDDASQIGQALTHIGRPEDAAAFERALAPAADGRAAACVLALGGAGGEGRRLHCVVRPLTDEHRLLEFSEGPAGALQRGLVDILDQLPVAIEIYDKNFFGTFYNKASDELFLYEEKVIVHHDEWWEFGFPDPLERAAAFSEWVAKMEVARRDGTIQFSEWKVRCRDGSTRIVQFRYRWVGESYVLALWDVTTERQTEEHLRHLAVSDPLTGLWNRRRLIEEGQRELELGATAGKECSLLIVDIDRFKSINDNHGHAAGDEVLRTVAQRGLSQLRRSDVMARIGGEEFAVLLPGTSALEARTIAARLLRAIRVPVVIGDDVVIEVTASIGGTGSTPEDDMDALMARCDRALYAAKTGGRNRVVFDDDISPPTDRAASSG
>NC_014217.1|WP_041783246.1|2387138_2387351_-|hypothetical-protein
MLDRTSMLCAHCPRCGRRSAIGRADAGALAQLSPDEPAPRLRCDMCGGRRVKLFNARGPMEMLAFLSGRL
>NC_014217.1|WP_013167085.1|2399233_2400787_-|2-isopropylmalate-synthase
MSNDKNHVVIFDTTLRDGEQCPGASMTLEEKLEVADLLDEMGVDVIEAGFPIASNGDFEAVAEIARRTKNAVIAGLARAIPADIARAGEAVRHAKRPRIHTFVSTSPIHLQHQMRKSEAEVIEIITATVAQARNLVDNVEWSAMDATRTPIEYLVRCVDTAIKAGATTINLPDTVGYATPQEYEAMFRQVRERVPGSDKVVFSAHCHDDLGLAVANSLAALAGGARQIECTINGLGERAGNAALEEVVMAIRTRGDVLPYATGIEAGMLTRASKLVSAVTSFPVQYNKAIVGRNAFAHESGIHQDGMLKNNTTYEIMTPESVGVSKTSLVMGKHSGRAAFRDKLKALGYELGENALNDAFARFKDLADRKKVVYDEDIEALVDQEIAAAHDRVKLVSLSVIAGTRGPQRATMKMEVDGQVFTEEAEGNGPVDATFNCIKAILPHTAALALYQVHAVTEGTDAQAEVSVRLEDGDKAVTGRGSDPDTLVASAQAYIIALNKLQTKRNSLNAQAQPAAE
>NC_014217.1|WP_013167086.1|2401325_2402897_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MSDTTANAGTAPRASSEGRRMFAFLCMVFGMFMAILDIQIVSASLAEIQAGLAASSDEISWVQTSYLIAEVVMIPLSGFLSRALSTRWLFVASAAGFTLMSFMCATATSIHEMIVYRALQGFLGGGMIPTVFAAAYSVFPREKQPVIAPLIGLVATLAPTIGPTIGGYLTDLFSWHWLFLVNIVPGIFVIIATATLVDFDEPDLSLLDRFDWWGLLFMAGFLGSLEFVLEEGPTNDWFEDEAIFIFAIVGAVSSVAFFARVLMAKEPVVDLKAFLNRNFSVGSAFSFVLGIGLYGLTYLYPLYLARVRGYSALMIGETMFVSGLAMFLTAPLAGRLVAKVDPRMMIAFGFGAFAVGTWQMTGMTQDWDFWELLWPQILRGVGLMMAMIPINNISLGTLPPAQLKNASGLFNLMRNLGGAVGLALINTVLNDRWDLHLARLHENVQWASSVAVERLDAMTRSLSMLGSDAETAALKKMAGQVRIQAEVMAFSDVFLALTALFVLLLFASPLMSRPKNAGGGGGH
>NC_014217.1|WP_144296078.1|2402908_2404111_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MAETAEAERPQTNEPVPITSRRPAEAPASAPAEAEQAAPPKRSRRKLVFGAILIAALAGGAWYGLDWWRVGRFLVSTDDAYVGADTSILAAKVGGHIVSVEVETNHPVKAGDVIARIDDGDYVLALKAAEDKIATQQATIDRYGQQISAGQASVDQARAQLVADEAELNRSQLEFDRQSELVKSQFSSKATLDNARADRDKAQAAVDASKASVASAQANIAVLEAQRTEAARVLDEYRTSRDQAQRDLDFTVVKAPFDGVMGNRAVQVGQLVQPGTRLAALVPLDKVYVDANFKETQLGELKPGQTVDVEVDAYPDEQFHGRVVSVAPASGSVFSLLPPENATGNFTKIVQRVPVRIELDAAAREKAELRPGMSVIATVDTRTGEGRNGATRVGDSRTAE
>NC_014217.1|WP_013167088.1|2404271_2404928_+|TetR/AcrR-family-transcriptional-regulator
MTTTDLDTVAAGAGTARSEPESAKRRDIIDGARRVFFDKGFDGASMDEVAKAAGVSKATIYVYFGGKEELFEALVRNDRARSAEHLFEVDPSIDDVAEVLRRIGISFMTMMVQPDHIRLIRMVIGVAEKFPRIGQIFFLAGPCHGGKRLGELLRQQAELGRLKLDDELEAAHLFLNMCQSNHVKGLLFGNTATPTQEQIEETVNRAVRAFLAFYGTKG
>NC_014217.1|WP_013167089.1|2405022_2406240_-|class-I-SAM-dependent-methyltransferase
MRFLPHLLKRFVHKGRLVVIEPDGKRTFFGSGEDGPEVVMRIHDDKLDRELFLNPELVSAEAYMDGRLTFEDGSTVYDLLYLFSINRRGLASHPVQQALRRGWRALRRWHQSNPLKRAASNAQSHYDHPPEFYALWLDSRMIYSCAYFPTPETSLEDAQEAKLRHIAAKLKLEPGMRVAEIGSGWGALAIYLAKLGVHVTAINVATEQLAESKKRAQAAGVADRITFFERDYRELTGTFDRVVSVGMMEHVGVGHFDDYFNTIKRLLAPGGFAMIHAIGRMSPPGTTAPFIRKYIFPGGYVPAMSEVFASLERTGLWTADCEVLRLHYYWTIRHWRLNFEAKRPEVVAMMGERFARMWEFYLAAVELGFLHGSNMVFQLLLANERDAVPVVRDFIVDEERALARG
>NC_014217.1|WP_013167090.1|2406645_2408022_-|malonyl-CoA-decarboxylase
MDAGTSFFGDLLGTIAERGRALLDIGRERRPAGAIRAAGIADLCERLLSGRGEASGVALAQEILVAYRTLRTGERVAFFETLANDFGPDAARLEAALAAHVKAPSTRTVAELHGASEPRRQELVRRLNLAPGATGRLVAMRADLLDALARRPDLADVDRDFVHLFTSWFNRGFLVLRRIDWSTPASVLEKIIRYEAVHEIRDWNDLRARVDSPDRRCYAFFHPALVDEPLIFVEVALTRDIPEAIAPILEAKRTPLDPANAKTAVFYSISNCQTGLGGVSFGNFLIKQVVEEISREFPKLTNFVTLSPVPRFRAFVEAERANPASAVLTAEDRAALDAFEAGTGDDEARRTLRPVIEALAAHYFLVARSAKGKPLDPVARFHLGNGARLERIDPFGDLSPRGMKQALGLMVNYRYVLDDIEKNHEAFFDRGTIVASPQVKKLLRADSHPVPAVREAAG
>NC_014217.1|WP_013167091.1|2408115_2409456_-|Nramp-family-divalent-metal-transporter
MLDRLQAEAAGWRRERGEKALAEVHGSIAVPKKSGIWRFFAFMGPGYLVATGYMDPGNWATSLAGGSKFGYGLLTVALLSNMIAILLQALCSRLGVASGRDLAQACRDAFPRPVGFVLWLLAEAAICATDLAEVIGTAIGLNLLFGIPLEIGVVITALDVFLILWLQNLGFRFVEALVVALLAVIAACFGIQIALADPNWGEVIRGFAPTTEIVRNPDMLYLALGILGATVMPHNLYLHSAIVQTRRREDTLEGKRDAIRLATWDSTLALMFALTINASILILAASTFHAGGAGEVADLGKAHELLNPLLGSAMAPTLFAIALLCCGINSTVTATIAGQAVMEGFLNIRLAPWLRRLITRAIAIVPAAAVTIAYGERGAGSLLILSQVILSLQLPFAVVPLIMFTADKRKMGVLVAPRWQTVLAVLAAALIISLNAKLVFDFITGA
>NC_014217.1|WP_013167092.1|2409661_2410405_+|DUF3750-domain-containing-protein
MLRAARFTLLSFALLFALPLGAHALVQWHEVDWTRSWHSADWSSTGTLPPAAAHPQAMVRIYAARVGRWRGIFAVHSWIVFKEPGAPAYERYDKVGWGRPIRHNGYAPDGRWYGNDPEVVFEATGADAEHLIPKLREAVESYPYALAGDYHVWPGPNSNTFTAYVVSQVPEMAVALPPTAIGKDFPIDGDWIGLAPSRTGLRVSFDGYAGLTLAWVEGVEINLFGAIAGLDIRRPGIKLPGFGRIGI
>NC_014217.1|WP_013167093.1|2410528_2411347_+|lytic-murein-transglycosylase
MIDHVIKCLKRAGLVAALLAPLATPALGAPCGDTGAGFDAWLRDFRQAAAAQGISPGAVRALDGLSYDTRVISLDRNQKHFKQSFEQFVANRVGAGRISKGKAMLRQHAGLLARIEQRFGVPGPILVAIWGMETDFGVNQGKMPVFRSLATLAYDCRRSGFFTGQLLDALRIVQRGDLSIGEMRGAWAGELGQTQFMPTSYVRFAVDFDGNGHADLIRSVPDVLASTANYLRGYGWSGPSWENGANMGALRGWNKAEVYARSIAYFATRLTQ
>NC_014217.1|WP_013167094.1|2411548_2411842_+|GIY-YIG-nuclease-family-protein
MGAFVYMLRCADGSYYVGSTRGTLEQRLVEHQSGAFPGYTFRRRPVTLIWSEHFSGITDAIAAERQIKGWSRAKKEALARGDWELIRAAARRPSGRE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014217_2	2.1\|2398386\|40\|NC_014217\|CRISPRCasFinder	2398386-2398425	40	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	664422-664461	9	0.775
NC_014217_2	2.1\|2398386\|40\|NC_014217\|CRISPRCasFinder	2398386-2398425	40	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	232750-232789	10	0.75

1. spacer 2.1|2398386|40|NC_014217|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 9, identity: 0.775

ggcggccgagcagcagcgcgcccagcaggaacgggctcgc	CRISPR spacer
cgaggccgagcagcgccgcgcccagcaggaatatgagcgc	Protospacer
 * ***********. ***************.. *  ***

2. spacer 2.1|2398386|40|NC_014217|CRISPRCasFinder matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 10, identity: 0.75

ggcggccgagcagcagcgcgcccagcaggaacgggctcgc	CRISPR spacer
agcggccgagcagctgcgcgcccggcaggaaggcatagcc	Protospacer
.************* ********.******* * ..   *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4583 : 47677

Sinorhizobium_phage(23.53%)

head,portal,protease,capsid,tRNA,tail,terminase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041781866.1\|4583_5234_+	hypothetical protein	A0A291AUT5	Sinorhizobium_phage	8.1e-94	75.1
WP_013164850.1\|5230_6295_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013164851.1\|6306_6900_+	hypothetical protein	NA	NA	NA	NA
WP_013164852.1\|6983_7343_+	HNH endonuclease	I3ULZ4	Rhodobacter_phage	1.1e-28	56.8
WP_013164853.1\|7442_7940_+	hypothetical protein	NA	NA	NA	NA
WP_013164854.1\|7939_9658_+\|terminase	terminase large subunit	I3ULZ6	Rhodobacter_phage	1.5e-115	41.6
WP_013164855.1\|9662_10994_+\|portal	phage portal protein	A0A141GEV9	Brucella_phage	1.2e-102	51.6
WP_144296044.1\|11007_11865_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A141GEW1	Brucella_phage	1.2e-68	50.8
WP_144296045.1\|12036_13257_+\|capsid	phage major capsid protein	Q3HQT0	Burkholderia_phage	2.3e-129	58.0
WP_013164858.1\|13323_13587_+	hypothetical protein	NA	NA	NA	NA
WP_013164859.1\|13590_13908_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_013164860.1\|13910_14261_+\|head	phage head closure protein	A0A141GEW5	Brucella_phage	4.9e-13	45.6
WP_013164861.1\|14260_14455_+	hypothetical protein	NA	NA	NA	NA
WP_013164862.1\|14441_14912_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_013164863.1\|14908_15331_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013164864.1\|15388_15835_+	hypothetical protein	NA	NA	NA	NA
WP_013164866.1\|16397_18404_+	tape measure protein	J9SH65	Pseudomonas_phage	8.8e-30	38.5
WP_013164867.1\|18406_19057_+	hypothetical protein	NA	NA	NA	NA
WP_013164868.1\|19053_19680_+	DUF2163 domain-containing protein	A0A2D2W208	Sinorhizobium_phage	1.3e-32	42.9
WP_013164869.1\|19696_20101_+	hypothetical protein	NA	NA	NA	NA
WP_013164870.1\|20104_22708_+	hypothetical protein	A0A2D2W226	Sinorhizobium_phage	4.1e-88	34.2
WP_041781868.1\|22740_24039_+	hypothetical protein	NA	NA	NA	NA
WP_013164872.1\|24048_25224_+	DUF2793 domain-containing protein	A0A0S2SY45	Pseudomonas_phage	1.6e-10	35.8
WP_013164873.1\|25242_26691_+	hypothetical protein	NA	NA	NA	NA
WP_013164874.1\|26769_26967_-	hypothetical protein	NA	NA	NA	NA
WP_013164875.1\|27002_27236_+	hypothetical protein	NA	NA	NA	NA
WP_013164876.1\|27222_27813_+	lysozyme	L7TM06	Rhizobium_phage	2.6e-38	46.9
WP_013164877.1\|27812_28172_+	hypothetical protein	NA	NA	NA	NA
WP_144295920.1\|28089_28425_+	hypothetical protein	NA	NA	NA	NA
WP_013164879.1\|28414_28699_+	hypothetical protein	NA	NA	NA	NA
WP_013164880.1\|28682_28892_+	hypothetical protein	NA	NA	NA	NA
WP_013164881.1\|29185_30901_+	hypothetical protein	NA	NA	NA	NA
WP_144295921.1\|30968_32042_-	hypothetical protein	NA	NA	NA	NA
WP_144295922.1\|32030_32888_+	DUF982 domain-containing protein	NA	NA	NA	NA
WP_013164883.1\|32884_33166_-	hypothetical protein	NA	NA	NA	NA
WP_013164884.1\|33272_33494_+	hypothetical protein	NA	NA	NA	NA
WP_013164885.1\|33486_33882_+	hypothetical protein	NA	NA	NA	NA
WP_013164886.1\|33873_34557_-	SOS response-associated peptidase	A0A291AUP1	Sinorhizobium_phage	1.1e-51	45.8
WP_013164887.1\|34563_34791_-	hypothetical protein	NA	NA	NA	NA
WP_041782566.1\|35167_35503_-	hypothetical protein	NA	NA	NA	NA
WP_013164889.1\|35682_38481_-	[protein-PII] uridylyltransferase	NA	NA	NA	NA
WP_013164890.1\|38688_39270_-	PRC-barrel domain-containing protein	NA	NA	NA	NA
WP_013164891.1\|39423_39855_-	hypothetical protein	NA	NA	NA	NA
WP_013164892.1\|40076_41405_-	PAS domain-containing protein	NA	NA	NA	NA
WP_013164893.1\|41412_42216_-	response regulator	NA	NA	NA	NA
WP_013164894.1\|42421_42661_+	hypothetical protein	NA	NA	NA	NA
WP_013164895.1\|42657_43209_+	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	8.4e-07	29.4
WP_013164896.1\|43314_43494_-	DUF1328 domain-containing protein	A0A0N7CBR2	Salmonella_phage	6.6e-06	61.2
WP_013164897.1\|43694_44594_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013164898.1\|44857_46054_-	DNA recombination protein RmuC	NA	NA	NA	NA
WP_013164899.1\|46165_46714_+	peptide deformylase	E3SLL2	Synechococcus_phage	5.9e-21	41.9
WP_013164900.1\|46759_47677_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	3.4e-05	33.0

DBSCAN-SWA_2

584895 : 595233

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013165396.1\|584895_586287_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.0e-77	39.0
WP_144296051.1\|586283_588131_-	glycosyltransferase	M1HVI2	Paramecium_bursaria_Chlorella_virus	1.7e-80	41.1
WP_013165398.1\|588223_589210_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	2.2e-42	35.1
WP_013165399.1\|589206_590217_-	SDR family oxidoreductase	A0A2K9KZK0	Tupanvirus	6.8e-71	43.0
WP_013165400.1\|590641_591994_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_013165401.1\|591990_592665_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.5e-26	34.1
WP_013165402.1\|593109_595233_-	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	7.9e-13	34.8

DBSCAN-SWA_3

724987 : 749163

Paracoccus_phage(14.29%)

head,portal,protease,capsid,tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013165532.1\|724987_725959_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013165533.1\|726093_727074_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_144295936.1\|727322_727934_+	hypothetical protein	NA	NA	NA	NA
WP_013165534.1\|728351_728885_+	hypothetical protein	NA	NA	NA	NA
WP_041781954.1\|728850_730173_+	DNA-packaging protein	A0A0K1LMR9	Caulobacter_phage	2.0e-78	42.9
WP_013165536.1\|730174_731317_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_013165537.1\|731445_732615_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	3.4e-74	42.3
WP_013165538.1\|732678_732867_+	hypothetical protein	NA	NA	NA	NA
WP_013165539.1\|732863_733031_+	hypothetical protein	NA	NA	NA	NA
WP_041781955.1\|733027_733597_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	9.2e-33	50.7
WP_013165541.1\|733827_735096_+\|capsid	phage major capsid protein	A0A2D1GNH4	Pseudomonas_phage	8.0e-61	38.0
WP_013165542.1\|735173_735380_-	hypothetical protein	NA	NA	NA	NA
WP_013165543.1\|735580_736300_-\|protease	trypsin-like serine protease	Q6JPG5	Neodiprion_lecontei_nucleopolyhedrovirus	4.4e-08	28.6
WP_013165544.1\|736401_736968_+\|head,tail	phage head-tail connector protein	A0A0F7L420	uncultured_marine_virus	1.5e-06	29.0
WP_013165545.1\|736964_737285_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_013165546.1\|737358_737763_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013165547.1\|737988_738396_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_013165548.1\|738573_738927_+	gene transfer agent family protein	NA	NA	NA	NA
WP_144296052.1\|738965_739124_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_013165550.1\|739139_739748_+\|tail	phage tail tape measure protein	A0A1B2AQ26	Escherichia_phage	4.0e-10	52.0
WP_013165551.1\|739747_740389_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	5.4e-50	49.5
WP_013165552.1\|740385_741249_+	DUF2163 domain-containing protein	A0A0K1Y6Z2	Rhodobacter_phage	4.0e-48	45.2
WP_013165553.1\|741248_741680_+	C40 family peptidase	F4YXU4	Roseobacter_phage	1.5e-27	44.9
WP_013165554.1\|741796_745699_+\|tail	glycoside hydrolase/phage tail family protein	A0A0K1LLC1	Rhodobacter_phage	2.0e-235	40.4
WP_013165555.1\|745991_746681_+	DUF2793 domain-containing protein	A0A1V0DY81	Dinoroseobacter_phage	2.5e-45	44.3
WP_013165556.1\|746692_746998_+	hypothetical protein	NA	NA	NA	NA
WP_013165557.1\|746999_747875_+	hypothetical protein	A0A2H4PAN7	Aphanizomenon_phage	1.7e-17	46.2
WP_144295937.1\|747882_748350_-	hypothetical protein	NA	NA	NA	NA
WP_013165559.1\|748365_749163_+	glycoside hydrolase family 108 protein	A0A1V0DY74	Dinoroseobacter_phage	7.5e-41	44.7

DBSCAN-SWA_4

1733280 : 1746482

uncultured_Mediterranean_phage(62.5%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013166484.1\|1733280_1736184_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	64.2
WP_013166485.1\|1736283_1736439_-	hypothetical protein	NA	NA	NA	NA
WP_013166486.1\|1736738_1737296_+	single-stranded DNA-binding protein	A0A0U2C0X4	Paracoccus_phage	2.3e-44	73.9
WP_041782109.1\|1737386_1738013_-	MarC family protein	NA	NA	NA	NA
WP_013166488.1\|1738309_1741066_+	DNA gyrase subunit A	A0A1B1IVS2	uncultured_Mediterranean_phage	2.0e-77	42.9
WP_013166489.1\|1741154_1741736_+	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	5.2e-15	34.2
WP_013166490.1\|1741807_1742317_+	pantetheine-phosphate adenylyltransferase	NA	NA	NA	NA
WP_013166491.1\|1742358_1742913_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	1.4e-38	54.0
WP_013166492.1\|1742952_1743411_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	4.8e-32	50.6
WP_013166493.1\|1743495_1744590_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_041783074.1\|1744589_1745735_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.3e-98	51.7
WP_013166495.1\|1745882_1746482_-	NAD(P)H:quinone oxidoreductase	M1IAZ8	Acanthocystis_turfacea_Chlorella_virus	4.8e-16	35.8

DBSCAN-SWA_5

1960212 : 1971770

uncultured_Mediterranean_phage(81.82%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013166683.1\|1960212_1960554_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.6e-14	43.5
WP_013166684.1\|1960751_1961648_+	ATP-binding protein	NA	NA	NA	NA
WP_013166685.1\|1961697_1962873_-	peptidoglycan DD-metalloendopeptidase family protein	Q8SBN9	Clostridium_phage	4.5e-18	42.7
WP_049785719.1\|1962981_1963647_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.3e-30	48.2
WP_013166687.1\|1963689_1964454_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.7e-37	39.0
WP_013166688.1\|1964575_1966060_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.2e-93	43.4
WP_013166689.1\|1966129_1966921_-	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	5.9e-46	43.4
WP_013166690.1\|1966917_1967733_-	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_013166691.1\|1967790_1968009_-	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	3.0e-08	65.9
WP_013166692.1\|1968076_1969156_-	ABC transporter ATP-binding protein	F2Y165	Organic_Lake_phycodnavirus	1.0e-08	26.5
WP_013166693.1\|1969193_1969925_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.2e-39	49.4
WP_013166694.1\|1969921_1970734_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.9e-31	35.0
WP_187291138.1\|1970753_1971770_-	beta-N-acetylhexosaminidase	A0A1B1IVS3	uncultured_Mediterranean_phage	5.6e-25	43.3

DBSCAN-SWA_6

2115711 : 2176032

Erysipelothrix_phage(21.43%)

head,portal,protease,tRNA,capsid,integrase,tail,terminase

attL 2155210:2155228|attR 2167307:2167325

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013166815.1\|2115711_2117712_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.3e-121	36.9
WP_013166816.1\|2117886_2120574_+	hypothetical protein	NA	NA	NA	NA
WP_144296072.1\|2120627_2120915_-	membrane protein insertion efficiency factor YidD	NA	NA	NA	NA
WP_013166819.1\|2121622_2122069_-	iron-sulfur cluster assembly scaffold protein	NA	NA	NA	NA
WP_013166820.1\|2122324_2122963_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	2.6e-44	48.4
WP_013166821.1\|2122979_2123465_+	phosphoribosyl-AMP cyclohydrolase	NA	NA	NA	NA
WP_013166822.1\|2123743_2124175_-	CBS domain-containing protein	NA	NA	NA	NA
WP_013166823.1\|2124349_2125123_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_041782156.1\|2125387_2126041_+	transglutaminase-like cysteine peptidase	NA	NA	NA	NA
WP_013166825.1\|2126335_2126866_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_013166826.1\|2126872_2127085_-	DUF3126 family protein	NA	NA	NA	NA
WP_013166827.1\|2127170_2128022_-	serine O-acetyltransferase	NA	NA	NA	NA
WP_013166828.1\|2128233_2128986_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_013166829.1\|2129072_2129432_-	DUF4087 domain-containing protein	NA	NA	NA	NA
WP_013166830.1\|2129444_2130431_-	hypothetical protein	NA	NA	NA	NA
WP_013166831.1\|2130771_2131020_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_013166832.1\|2131035_2132214_+	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_041783171.1\|2132402_2133272_+	DMT family transporter	NA	NA	NA	NA
WP_013166834.1\|2133396_2134425_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_013166835.1\|2134720_2138551_+	trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_013166836.1\|2138683_2139217_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_013166837.1\|2139247_2140150_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013166838.1\|2140270_2140993_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_013166839.1\|2141003_2141357_+	Atu4866 domain-containing protein	NA	NA	NA	NA
WP_081441027.1\|2141368_2142715_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_144295977.1\|2142869_2143730_+	EamA family transporter	NA	NA	NA	NA
WP_013166842.1\|2143822_2144281_+	DUF4126 family protein	NA	NA	NA	NA
WP_013166843.1\|2144280_2145669_+	FAD-containing oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.5e-57	31.9
WP_013166844.1\|2145689_2147423_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_013166845.1\|2147415_2148492_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-27	30.9
WP_013166846.1\|2148532_2149636_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013166847.1\|2149946_2151974_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_013166848.1\|2152100_2153369_-	FAD-binding protein	NA	NA	NA	NA
WP_013166849.1\|2153388_2154498_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_013166850.1\|2154678_2155953_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
2155210:2155228	attL	NA	NA	NA	NA
WP_013166851.1\|2155956_2157540_-	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0SI18	Klosneuvirus	3.3e-56	32.5
WP_013166852.1\|2157830_2159006_+	MFS transporter	NA	NA	NA	NA
WP_041782161.1\|2159018_2160506_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_041783175.1\|2160838_2161345_+	flavin reductase	Q9KX93	Enterobacteria_phage	9.4e-05	34.1
WP_013166855.1\|2161398_2162133_-	glucose 1-dehydrogenase	NA	NA	NA	NA
WP_013166856.1\|2162220_2162619_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013166857.1\|2162634_2163027_-	RidA family protein	NA	NA	NA	NA
WP_013166858.1\|2163082_2163229_-	hypothetical protein	NA	NA	NA	NA
WP_013166859.1\|2163563_2165255_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_187291109.1\|2165518_2166649_+\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	9.3e-53	35.0
WP_013166861.1\|2166641_2167016_+	gene transfer agent family protein	NA	NA	NA	NA
WP_013166862.1\|2167112_2167619_+\|head,protease	HK97 family phage prohead protease	A0A0R6PIR7	Moraxella_phage	7.9e-20	40.3
2167307:2167325	attR	NA	NA	NA	NA
WP_013166863.1\|2167629_2168769_+\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	3.6e-36	33.9
WP_013166864.1\|2168772_2169348_+	hypothetical protein	NA	NA	NA	NA
WP_041783183.1\|2169347_2169695_+	HNH endonuclease	Q38456	Bacillus_phage	3.4e-14	44.7
WP_041782163.1\|2169697_2170495_-	HNH endonuclease	NA	NA	NA	NA
WP_187291110.1\|2170672_2170927_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_013166868.1\|2170928_2171333_+	HK97 gp10 family phage protein	B4UTQ0	Rhizobium_phage	1.4e-11	38.2
WP_013166869.1\|2171332_2171740_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013166870.1\|2171736_2172054_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_013166871.1\|2172050_2172464_+\|terminase	phage terminase small subunit P27 family	A0A1B3AYP2	Gordonia_phage	1.0e-09	37.7
WP_013166872.1\|2172463_2174083_+\|terminase	terminase	A0A0U2C138	Paracoccus_phage	2.9e-39	29.1
WP_013166873.1\|2174082_2176032_+\|tail	tail tape measure protein TP901 core region	A0A291AUM6	Sinorhizobium_phage	1.3e-41	36.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014217

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection