CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_014388	Butyrivibrio proteoclasticus B316 chromosome 2, complete sequence	0 crisprs	cas14k,WYL,RT	0	0	1	0
NC_014390	Butyrivibrio proteoclasticus B316 plasmid pCY186, complete sequence	0 crisprs	WYL,DEDDh	0	0	0	0
NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	1 crisprs	PD-DExK,cas14j,DEDDh,cas14k,c2c10_CAS-V-U3,cas12a	0	10	1	0
NC_014387	Butyrivibrio proteoclasticus B316 chromosome 1, complete sequence	5 crisprs	c2c10_CAS-V-U3,DEDDh,RT,csa3,WYL,DinG	0	1	1	0

1. NC_014387

CRISPR-Cas detection and classification

Crispr_ID: NC_014387_1

• CRISPR_ID: NC_014387_1
• CRISPR_location: 270736-270836
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014387_1

Consensus_repeat	Method
TGTGCCGCAAGAGCATGTCCATG	CRISPRCasFinder

spacers of NC_014387_1

>1.1|270759|55|NC_014387|CRISPRCasFinder
CGCCGGTAGCTGGTCTTGGCTTACCGCAGTTAGTGCAGAAATTGCCGCTGTTAGG

CRISPR arrays and Neighbor proteins around NC_014387_1

CRISPR arrays

The CRISPR arrays of NC_014387_1

>merge|NC_014387|1|270736-270836|CRISPRCasFinder
TGTGCCGCAAGAGCATGTCCATGCGCCGGTAGCTGGTCTTGGCTTACCGCAGTTAGTGCAGAAATTGCCGCTGTTAGGTGCGCCGCAAGAGCATGTCCATG

>NC_014387|1|1|270736-270836|CRISPRCasFinder
TGTGCCGCAAGAGCATGTCCATG	CGCCGGTAGCTGGTCTTGGCTTACCGCAGTTAGTGCAGAAATTGCCGCTGTTAGG
TGCGCCGCAAGAGCATGTCCATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014387.1|WP_013279626.1|279516_280320_+|FRG-domain-containing-protein	unknown	unknown	gnl|CDD|378073
NC_014387.1|WP_013279615.1|266816_268583_-|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NC_014387.1|WP_013279617.1|269598_270660_-|hypothetical-protein	unknown	unknown	gnl|CDD|131238
NC_014387.1|WP_013279623.1|275925_276798_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_014387.1|WP_013279612.1|263577_263982_+|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_042257284.1|276845_278471_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270451
NC_014387.1|WP_013279614.1|265132_266827_-|diguanylate-cyclase	unknown	unknown	gnl|CDD|225109
NC_014387.1|WP_013279607.1|256985_257735_-|DUF975-family-protein	unknown	unknown	gnl|CDD|283754
NC_014387.1|WP_013279613.1|263991_265119_+|citrate-transporter	unknown	unknown	gnl|CDD|238537
NC_014387.1|WP_143754240.1|281168_281948_+|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_013279616.1|268702_269569_-|TPM-domain-containing-protein	unknown	unknown	gnl|CDD|377378
NC_014387.1|WP_013279627.1|280337_280997_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239516
NC_014387.1|WP_013279611.1|261771_263556_+|glycoside-hydrolase-family-27-protein	unknown	unknown	gnl|CDD|269893
NC_014387.1|WP_013279622.1|275007_275898_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_014387.1|WP_042256311.1|273916_275011_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226359
NC_014387.1|WP_013279609.1|258289_258697_-|DUF4190-domain-containing-protein	unknown	unknown	gnl|CDD|379388
NC_014387.1|WP_034475364.1|278541_279339_+|hypothetical-protein	unknown	unknown	gnl|CDD|236766
NC_014387.1|WP_013279619.1|271991_273599_+|DUF4445-domain-containing-protein	unknown	unknown	gnl|CDD|226410
NC_014387.1|WP_013279608.1|257757_258255_-|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_013279620.1|273674_273845_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014387.1|WP_013279626.1|279516_280320_+|FRG-domain-containing-protein	gnl|CDD|378073	pfam08867, FRG, FRG domain. This presumed domain contains a conserved N-terminal (F/Y)RG motif. It is functionally uncharacterized.	9.26008e-23
NC_014387.1|WP_013279615.1|266816_268583_-|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	9.43028e-28
NC_014387.1|WP_013279617.1|269598_270660_-|hypothetical-protein	gnl|CDD|131238	TIGR02183, Glutaredoxin_1_Grx1., Glutaredoxin, GrxA family. Glutaredoxins are thioltransferases (disulfide reductases) which utilize glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. Together these components compose the glutathione system. Glutaredoxins utilize the CXXC motif common to thioredoxins and are involved in multiple cellular processes including protection from redox stress, reduction of critical enzymes such as ribonucleotide reductase and the generation of reduced sulfur for iron sulfur cluster formation. Glutaredoxins are capable of reduction of mixed disulfides of glutathione as well as the formation of glutathione mixed disulfides. This model includes the E. coli glyutaredoxin GrxA which appears to have primary responsibility for the reduction of ribonucleotide reductase.	0.00292777
NC_014387.1|WP_013279623.1|275925_276798_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.38192e-74
NC_014387.1|WP_042257284.1|276845_278471_+|extracellular-solute-binding-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.10434e-36
NC_014387.1|WP_013279614.1|265132_266827_-|diguanylate-cyclase	gnl|CDD|225109	COG2199, COG2199, c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal transduction mechanisms].	3.38004e-35
NC_014387.1|WP_013279607.1|256985_257735_-|DUF975-family-protein	gnl|CDD|283754	pfam06161, DUF975, Protein of unknown function (DUF975). Family of uncharacterized bacterial proteins.	1.07114e-11
NC_014387.1|WP_013279613.1|263991_265119_+|citrate-transporter	gnl|CDD|238537	cd01117, YbiR_permease, Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.	6.41818e-55
NC_014387.1|WP_013279616.1|268702_269569_-|TPM-domain-containing-protein	gnl|CDD|377378	pfam04536, TPM_phosphatase, TPM domain. This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II.	5.76268e-31
NC_014387.1|WP_013279611.1|261771_263556_+|glycoside-hydrolase-family-27-protein	gnl|CDD|269893	cd14792, GH27, glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	1.02613e-46
NC_014387.1|WP_042256311.1|273916_275011_+|ABC-transporter-ATP-binding-protein	gnl|CDD|226359	COG3839, MalK, ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism].	1.58015e-142
NC_014387.1|WP_013279622.1|275007_275898_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.39294e-54
NC_014387.1|WP_013279609.1|258289_258697_-|DUF4190-domain-containing-protein	gnl|CDD|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	2.66045e-05
NC_014387.1|WP_034475364.1|278541_279339_+|hypothetical-protein	gnl|CDD|236766	PRK10811, rne, ribonuclease E; Reviewed.	0.00373213
NC_014387.1|WP_013279619.1|271991_273599_+|DUF4445-domain-containing-protein	gnl|CDD|226410	COG3894, COG3894, Uncharacterized metal-binding protein [General function prediction only].	4.00191e-56
NC_014387.1|WP_013279627.1|280337_280997_+|NUDIX-hydrolase	gnl|CDD|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	3.3908e-15

Protein sequences

>NC_014387.1|WP_013279617.1|269598_270660_-|hypothetical-protein
MALHEYECPACGGAMEFNPKTQKLKCPFCDSEFDVKDYVANHNSSSTGELADEYTNENTTDDGQQLYIYKCGSCGGEILTTESLGSTKCPFCSNNVVVSEKFSGQFKPDYIIPFKCTKEDAMKTYREHVKSKKLVPKVFLDENHIDEIKGVYVPFWLFDATMSFDGSYEGTKVRTWQDSKYIYTETKYYDVKRSGTEDFAFVPVDGSKEMPDDLMESLEPFDHNEMVPFNMGYLAGFLANKYNNPADAMKPRAMDRIKASIISDFKATINGYSGLRSLRENTGVVSSSYKYAMYPVYILNTTWKGENYLFAMNGQSGKFVGNLPFSWLQAIKYYIPFAAIGTLISFLVYYFII
>NC_014387.1|WP_013279616.1|268702_269569_-|TPM-domain-containing-protein
MRIIIKIHKKIALALLAIMIAAFCVPTVTSFASDGQLWDDYVMPSTRQKERLLDNAELLTASEKQEILGLLNSISSTHQANVAILTVNSHRGSIQDYADDYFDYNGFQADYDGSGILFMLSMEDREWAISTHGTAAYVFTDYGQEELMDEMIPYLRDDDYYDAFKAFIDVSERYFTLYEEGTPYDVDYKDTSPAAVTRALLICILIGLVIGFIPIGIMSLDLKSVKASVNAAGYQIHNGLHMGLHTDTYIRSSTSRTKIPENNSNSGGGSSFHVSSSGSSHGGSSGHF
>NC_014387.1|WP_013279615.1|266816_268583_-|diguanylate-cyclase
MKTKRRIRTILLTLCAVLIMGLAIAFLGTDSFKSPMNYDLVQLEDGWTVTHADKTYTPEQLSLADIGIANIGDVITLTRTLDKYDIDPVTIHFRSILSTVDVLLDGESIYSYGWDYVEKKQMLPKKQHFVLLPKDYPGKELTIIITPQENEAFSGISPIILGYIEDIARDISQSNRLALFIAVFLVMFGYMMIIISPILMYRGNHDLSITFSGVISVLLGLYILCFNDLFWLFTENAAFYTFLEYITLFLLPASILLFLYTARQINGHLIAMILGIINFGFAITTAILHLTNTIHICHFVTTLHVIALTEGIFVISSLGGSVYKRYRYPDEFRSKSMSTNMLLLGLLLFLGCSVIDIVKFNIKKYFSSGEMNTNINFLTVGALLFMMCLVLNYFFHCIEYINESNMKQQLEGLAYTDSLTSLANRSRCELTLAELSGDYTIISIDLDYLKYTNDNFGHLEGDRLISDFADILSNSFTDASLLGRMGGDEFIVVLPYVNDERLQRDISCFDDLMKHKNSKETHLKFSASYGYADSHDEKFYHTATAQDVYLLADARMYQMKNTHHKQSLGRLYDDLLKHADKEGGSNEK
>NC_014387.1|WP_013279614.1|265132_266827_-|diguanylate-cyclase
MKNKKRLPYLLASLFIIVVVIIGCRITLYRSADYEMIDLNDSWLMSINNSDFHEVSMWDSYKYFEGELKHGDHIIYKTVLPQSNIPNPVLFFRSRYTTLGCYIDGTKIYSYGDEYYKTGKFIGKMYHMIPLPSDYAGKTFVFDMYVGEPNAFKTLTAPILAAQTDISGKFVRDNLLIIATGMFTFVFGLMFLCIGLVFVNYVPEVRSLLVGSCFCMNLAAWLMTYYNILSLFIYTEKETEIEYFCMYIVVPYSYLLLYYIKNLKNDRGYKAIMLVSTAVPILQYALHYFFGIHLRVTLPLYHVVAVLGFVILIYYVAVSNKKNTKESPATLIQLVGLFAFDFGQFFHLIMYGFEVAGHQTNQSANKIVISSACLIFAACQLSTYLMYITETYAKRRENQSLSHLAYADGLTNLANRSKADKLMEELNSATDDYCIMSIDLNGLKDVNDKFGHPTGDRYLKEFAKVLSNTFGENDFSARIGGDEFLVVLRDANTKDISALIGRMNSALNVMNALYPDYKRSVAIGFAFKHESEKGNSHQVYLLADQRMYENKRKMHQELGIHPRL
>NC_014387.1|WP_013279613.1|263991_265119_+|citrate-transporter
MGSYADLWKKIKSDPVLYIAWILALISAFFVRPDKGYLDYIDFRSLGILWGLMVIIQGLKENSVFEKIGQLLMGRASKAWQLSAALIFMCFIGSMLITNDVALITFVPFGMLVLKSCQREDLMIPVIVFQTIAANLGSMATPVGNPQNLYLYGITQMSIGEFVLCMLPFTAAAALMLVLCIFLLPGKNKDIVINSEYGIVKEFGSRRQIVIYTVLFVIAILSVLRVIPWYVMAAVVLVMVAGMDYKILLRADYMLLLTFIGFFIFTGNMARIDSVKEFFNSVTSGKEFTVAVIASQFISNVPATLLLSGFTSNYKELLIGVNAGGLGTLIASMASLISFKFYSATYKERQKAYIVYFTVANLAFLAVFVLLHLFI
>NC_014387.1|WP_013279612.1|263577_263982_+|hypothetical-protein
MTEKEFFDLLLTRYSEEISEDLPAEGLGYYLEYFLDHYPSEKLELKITKKVAARILHEFMTYVLKWEDLEWGDAANLKDIYDCRVCSNAIAQVYERGIIGEAEPLVFGLNITLGREDGIRIIERFLSKIKEIDI
>NC_014387.1|WP_013279611.1|261771_263556_+|glycoside-hydrolase-family-27-protein
MTPDRLEAEGRFDSFDNGKVLFGKKKYRLPAMGWNSWNAFGSGNTEELTKAMADKFIELGLDKLGYKYIVLDDGCYKDQRVDGRLSNEDGKFPGGFRALSDYIHSKGLKFGMYNDIGTNLCAGAEVGTCGHEKEDAENYLEWGVDFLKVDNCYYLWDNATFSNPENARYTFAPNIRGIRIGAEEFPVIYGVHDGGEVSLAGIELTGERASREEDYITGIGTFDGTGPEASPVGLRSSELVFVVNADRDMDTTLCVNYASGKREGVGAWLQVAVGDEYYWDDFLDETPSEGDFIWSREISIKLKKGENRIRLMNHRRQENTLNSYARLLKKLNRLAPDNDIIYSACEWGKTQPQNWAYKVCDSWRILNDITFRVGRDGDPGVGTWTGDYTTSVATQYSKAVIMDEFAGLDKGWNDPDMMMIGMNGLNDVQNKTHMTMWCMMNSPLMLGLDLRRVHKGDTLYNIIANEDAISLNQDSLGIQAKRVFSSLAAKEPDKEYIRDIDRVDILCKPLSGNRFALSFINVSEKDTDKTYTIKLCDLKKALGDWIYKCDKYLVKDIWTGETTENETGEFSVNGLAACDNVTFIVSPASPVEMK
>NC_014387.1|WP_013279609.1|258289_258697_-|DUF4190-domain-containing-protein
MGDEDNQYFYNNYNYNKAHNELDKHVNLATLSLVLGLISIPFCFFMYTGIILGGIAVVMAILSKGAAERFLPQAKKGIVYGTIGVVLGYGVLVSSIHNIMTDPSYRQQLNQFSEQYYGESVDDMLKELGVQLESQ
>NC_014387.1|WP_013279608.1|257757_258255_-|hypothetical-protein
MSMIGAIGSGYGAYAGLGVTNRTPAEGSKPILNPNESTNKAPGKLSSPAECETCKNRKYQDGSDEMVSFKSAQHISPQSAASRVRGHEAEHVSNAYKDAAMNNGKVLQASVSIKTAVCPECGRVYVSGGETATKIKYSNEDNPYQKSRKAMDQQGLLGANIDLAG
>NC_014387.1|WP_013279607.1|256985_257735_-|DUF975-family-protein
MSTISTAQLKAIAKERALDRYGTLIFANILIFIIQVLISGITTVASYGNILIFIINQFINLIVSILLGILASGKAYLYMNLVYSQTISASDIFFGLKQQPQKAVVIQSVFVIANYLVTLPSSLILFYADQTSSIDLYLTNIIILIAGIVINIFIYLMYSQAFFLLHDFPDRSALELLKTSRRLMQGRKGKLFLLQLSFVPLYIFGIITLFVPLLWISVYRYASVAVFYQNLISEAANVSSSKEEQNGLN
>NC_014387.1|WP_013279619.1|271991_273599_+|DUF4445-domain-containing-protein
MEKNKLLITINTNGKKIRLQAPKRRQLKGLLSDAGVQYVLPCGGLGRCGKCRVRFLSGAPDVNSLDKSFLTEKEISDGFRLMCRCIVTSDCEIVLDDVAVKEEEIEVKKSFEIRVKQPLDEKDITGWGIAVDIGTTTLEAMLVGMNDEKTRQVFDIVSGINHQRKYGADVIARISAAAGGDGEKLCQSIREDIKTLIVELVNGREVNKLDYICITGNTTMLHLLRGYDVAGLGEYPYKAVNLDVENISAWELLGDLSEKDFPYLSETRAVLMPGISAFVGADIVSGIDAISMTKMKHKALFVDLGTNGEMAYWDGHKLFVTSTAAGPVFEAGGIVCGTAAIPGAIYGVHIEEKDGKYKVELETIKNKEPSGICGSGVLEAVSELVRNRIVDETGLLTKEYFETGFPLTDGENGIRIYQSDIRNVQLGKAAIAAAWSQLLGETDPEYIEISGGYSSSFDAKKIKYLKLFPQNSKIVLGASNAALVGCMYLLTDLLTSREAGDKAVKRLQKIAETAQVVELVNKADFAEKYVEAMSF
>NC_014387.1|WP_013279620.1|273674_273845_+|hypothetical-protein
MICDTCANYAYDDDWECYVCMVNMDEDDYGRMVAGGNKECPYYQDGDEYKVVRHQM
>NC_014387.1|WP_042256311.1|273916_275011_+|ABC-transporter-ATP-binding-protein
MKVTLEHVTKRFPNRNKKIKEDVIAVNDFNFEIPDGKLIGLLGPSGCGKSTALNLICGLEKPTEGRIIFGDTDVTDLPPQHRGVGLVFQNYALYPHLTVRENIRFPLENFRGDKKLSKEEMEEKVLEAARLVQIEELLDRRPSEMSGGQQQRVAIARALVKRPQVLLLDEPLSNLDARLRLQTREELKRIQLETGITTVFVTHDQEEAMSICDTIVVMKNGVLQQMGDPQRIYDEPINLFVASFLGTPQINTFKGRIADGGVYIGDARVLDAGGVSDRNVSVSIRPEGFIVDENGPLECEFVNREVMGRDTSYVAKHPLFVGENIRAIIPSEVVSTGVDGKIRFSLKPSKVHVFDENTNERIIL
>NC_014387.1|WP_013279622.1|275007_275898_+|sugar-ABC-transporter-permease
MKKNLTAWLCLLPAIAFLGVFMVYPLIDVFVYSFEEGYNFASQTFWGTGLYNYSYVLHDPYFIQALKNTFIIVIITVPLSTGIALLISLELSSIKALRDFFQTVYFLPYVTNTLAVGLVFMILFKKTAYSDGLISLLIQLFGGPSVDFIDGPYWAKMFVMCFYTIWIVMPFKILILTSALASVNPMYYKAAEVDATPKWRIFYKITLPMISPMVFYLVITGFIGAFKAYSDEVALFGTDLNAAGMNTIVGYVYDMLYGNSGGYPSYASAAALILFAIVFTITTINLMVSRKTVYYQ
>NC_014387.1|WP_013279623.1|275925_276798_+|carbohydrate-ABC-transporter-permease
MNENANKKLERQAVRNERLRKVVIYFLLTLWAILVLFPFYWMLLTSVKGYGAYNSEYVPRFFTLSPTLENYVTAFTAVSLGRYFFNTFVFTVLTTLLMMVVVVLSAFAFARLDFKGKDIVFSLFLSLMMIPNELVIITNYVTITNLDLRNTFMGLILPSVTSVFYIYLLKENFEQIPEELYKAAKVDGTSDFRYLWKVMLPISRPTIVTITILKVIECWNSYVWPRLITDDSNYFLVSNGIQEIRENGFGRENVPAMMAAVVVISVPLVVLFLIFRHKIMAGVARGGTKG
>NC_014387.1|WP_042257284.1|276845_278471_+|extracellular-solute-binding-protein
MVINIKRKITVFLGCVLASSCILTGCHGAKDSAGFEIPQELDENKKIELTFWAKNDTNVTQTAIYNKAIEDFEKLYPNITVNMRLYTDYGKIYNDVITNISTGTTPNVCITYPDHIATYLMGNNTVVPLDDLFADEKYGLGGSALKFDSPAVSEIVPEFLSECVIGDKHYALPYMRSTEACYINKTYVEKLGYELPDTLTWDFIWEVSEAAMEKNADGTFKVNGQNVMIPFIYKSTDNMMIQSLKQLGAGYSDQEGNILLFNDDTRGILKTIAEHTGSGAFSTFKISGYPANFLNAGQCIFAIDSTAGATWMGSKAPLLDISEDKVIDFETEVMAIPQYDPEKPSMISQGPSVCIFNKKDSQEVLASWLFAQYLLTNDVQIAYSETEGYLPVTTKAQSTAEYQDYLAGAGSDDDKHYDVKIKATKILMDNTENTFVTPVFNGSASVRDAAGQLIENVTKSVRRKKTVDDAYIDQLYEDVKALYHLDQGSTGNIGGKAELGKLPAASVALIAVLVTAWVLIGLYSLKEKLKTXKKMNKYLYL
>NC_014387.1|WP_034475364.1|278541_279339_+|hypothetical-protein
MKKTLAVVLTMGLALAFVGCGKQEVTEVAETATEAVSAVEEAATVAESVAAEVTEVAETADDAKSEGVMTYAEYAAAELDSEVVVETYVQAKQSWWEDKATFYTQDQDGAYFIYEMACSQEDYDKLVPGTKIKVTGVKSEWSGEVEIVDATYEIEDGNFVATAKDATDLLGKDELIDLQNQLVSFSDMTVEAVAFKNEQPGDDIYVTLSKDGANYEFCLEYYLNGSDEKFYNLVSGLEAGQTVDVEGFLYWYEGANPHLTNVTVK
>NC_014387.1|WP_013279626.1|279516_280320_+|FRG-domain-containing-protein
MIKEVHIDTLEELLPLLTEQEYRADLDRNRSPYIYRGMSDSSFTMYTSLSRNCKSRQNHLEPAILENFAKYAINDEPSIGSSVWRQMILGQHYGLPTRLLDWTQSALVGLNFAMTEENLEEMDKHDCMVWRINMSEMVELLPNNYKYAVYDKHSTIFTVDMLKELTGNSLKQYDRDMGNSAMVIIEPPSLNQRIINQHSFFAVVPMGIEDIEGFLDKNTKDTVKYVIDKNLRWRVRDMLDQLNMSERIVYPGLEGLSKWIARHYYVK
>NC_014387.1|WP_013279627.1|280337_280997_+|NUDIX-hydrolase
MTGPIITKDKVETILDKKFIRVFDLQYEEGKHYFDATRRPLDNIVATKTEEEFKTMLPDAVSCVVIVELPGKEPQLLLSYEYRYPTGRFLLSVPAGLMDPEDRDEENPIATTAIREIHEETGIVVDTKRDSVSVINPLLFSTPGMTDESNALALVILHLDNLDEMNQKGGVGSECFDGFSLIDKEKARELLKKGVDDKGHFYSVYTWSALMYFVSDMWK
>NC_014387.1|WP_143754240.1|281168_281948_+|hypothetical-protein
MSNISEIAANSGALEAIKNSGVKENSGVKSGNYGKTIGKAQLSEAGAKYYEELKKKYSNMDFVLVSKDMKEHAKQNAASYGNANKMVVLIDEEKIERMATDENFRAKYEGLISRAQSQMPALKSLAQQQGNVKSIGMQVNDNGTASFFAVMQKSSQSMTEKLAAKREAKKKAEKAAEKKAEKKEQHEEQLQKIKDKSSDGTNKVKNWEDIENDDDVEIIMASSVEELKSKIEAYNYNMRANNIQAPEEKLVGQSIDFRG

Crispr_ID: NC_014387_2

• CRISPR_ID: NC_014387_2
• CRISPR_location: 359304-359422
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014387_2

Consensus_repeat	Method
CCCTGAGAGATTGCTGATACAGGGCACTGAGC	CRISPRCasFinder

spacers of NC_014387_2

>2.1|359336|55|NC_014387|CRISPRCasFinder
TGCACATGAACCGCAGTCGATACATGTATTTGCATCGATAACGTACTGTGTATCT

CRISPR arrays and Neighbor proteins around NC_014387_2

CRISPR arrays

The CRISPR arrays of NC_014387_2

>merge|NC_014387|2|359304-359422|CRISPRCasFinder
CCCTGAGAGATTGCTGATACAGGGCACTGAGCTGCACATGAACCGCAGTCGATACATGTATTTGCATCGATAACGTACTGTGTATCTCCCTGAGAAATTGCTGATACAGGGCACTGAGC

>NC_014387|2|2|359304-359422|CRISPRCasFinder
CCCTGAGAGATTGCTGATACAGGGCACTGAGC	TGCACATGAACCGCAGTCGATACATGTATTTGCATCGATAACGTACTGTGTATCT
CCCTGAGAAATTGCTGATACAGGGCACTGAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014387.1|WP_042256331.1|366786_367845_+|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl|CDD|223088
NC_014387.1|WP_026662902.1|369142_369625_+|dCMP-deaminase-family-protein	unknown	unknown	gnl|CDD|238613
NC_014387.1|WP_034475745.1|355305_357357_+|DHH-family-phosphoesterase	unknown	unknown	gnl|CDD|226404
NC_014387.1|WP_013279682.1|370801_371293_-|DUF402-domain-containing-protein	unknown	unknown	gnl|CDD|377233
NC_014387.1|WP_013279669.1|349768_355177_+|CehA/McbA-family-metallohydrolase	unknown	unknown	gnl|CDD|227588
NC_014387.1|WP_013279676.1|365078_366782_+|SH3-domain-containing-protein	unknown	unknown	gnl|CDD|119353
NC_014387.1|WP_013279671.1|357360_357807_+|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NC_014387.1|WP_013279672.1|357808_359152_+|replicative-DNA-helicase	unknown	unknown	gnl|CDD|273206
NC_014387.1|WP_013279663.1|343406_345863_+|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl|CDD|223730
NC_014387.1|WP_013279664.1|345866_346757_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223730
NC_014387.1|WP_013279668.1|348481_349648_+|YibE/F-family-protein	unknown	unknown	gnl|CDD|377940
NC_014387.1|WP_013279666.1|347609_347906_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_014387.1|WP_143754242.1|371484_373938_+|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_013279674.1|359885_363416_+|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase	unknown	unknown	gnl|CDD|131231
NC_014387.1|WP_013279675.1|363561_364359_-|adaptor-protein-MecA	unknown	unknown	gnl|CDD|377506
NC_014387.1|WP_013279681.1|369632_370808_+|cell-wall-hydrolase	unknown	unknown	gnl|CDD|377847
NC_014387.1|WP_013279665.1|346757_347573_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_014387.1|WP_026662903.1|368433_369063_+|uracil-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234653
NC_014387.1|WP_026662904.1|367934_368372_+|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl|CDD|376799
NC_014387.1|WP_167531130.1|347965_348343_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379279

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014387.1|WP_042256331.1|366786_367845_+|threonylcarbamoyl-AMP-synthase	gnl|CDD|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	8.54832e-83
NC_014387.1|WP_026662902.1|369142_369625_+|dCMP-deaminase-family-protein	gnl|CDD|238613	cd01286, deoxycytidylate_deaminase, Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the enzyme is allosterically regulated by the ratio of dCTP to dTTP not only in eukaryotic cells but also in T-even phage-infected Escherichia coli, with dCTP acting as an activator and dTTP as an inhibitor.	3.23703e-50
NC_014387.1|WP_034475745.1|355305_357357_+|DHH-family-phosphoesterase	gnl|CDD|226404	COG3887, COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms].	7.02835e-150
NC_014387.1|WP_013279682.1|370801_371293_-|DUF402-domain-containing-protein	gnl|CDD|377233	pfam04167, DUF402, Protein of unknown function (DUF402). Family member FomD is a predicted protein from a fosfomycin biosynthesis gene cluster in Streptomyces wedmorensis. Its function is unknown.	6.22004e-15
NC_014387.1|WP_013279669.1|349768_355177_+|CehA/McbA-family-metallohydrolase	gnl|CDD|227588	COG5263, COG5263, FOG: Glucan-binding domain (YG repeat) [General function prediction only].	1.36146e-08
NC_014387.1|WP_013279676.1|365078_366782_+|SH3-domain-containing-protein	gnl|CDD|119353	cd02874, GH18_CFLE_spore_hydrolase, Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.	3.25779e-57
NC_014387.1|WP_013279671.1|357360_357807_+|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	8.52952e-62
NC_014387.1|WP_013279672.1|357808_359152_+|replicative-DNA-helicase	gnl|CDD|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_014387.1|WP_013279663.1|343406_345863_+|alpha/beta-hydrolase-fold-domain-containing-protein	gnl|CDD|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	2.65373e-25
NC_014387.1|WP_013279664.1|345866_346757_+|alpha/beta-hydrolase	gnl|CDD|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	4.37725e-24
NC_014387.1|WP_013279668.1|348481_349648_+|YibE/F-family-protein	gnl|CDD|377940	pfam07907, YibE_F, YibE/F-like protein. The sequences featured in this family are similar to two proteins expressed by Lactococcus lactis, YibE and YibF. Most of the members of this family are annotated as being putative membrane proteins, and in fact the sequences contain a high proportion of hydrophobic residues.	4.19307e-86
NC_014387.1|WP_013279666.1|347609_347906_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	3.78641e-23
NC_014387.1|WP_013279674.1|359885_363416_+|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase	gnl|CDD|131231	TIGR02176, pyruvate_flavodoxin/ferrodoxin_oxidoreductase, pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric. This model represents a single chain form of pyruvate:ferredoxin (or flavodoxin) oxidoreductase. This enzyme may transfer electrons to nitrogenase in nitrogen-fixing species. Portions of this protein are homologous to gamma subunit of the four subunit pyruvate:ferredoxin (flavodoxin) oxidoreductase.	0
NC_014387.1|WP_013279675.1|363561_364359_-|adaptor-protein-MecA	gnl|CDD|377506	pfam05389, MecA, Negative regulator of genetic competence (MecA). This family contains several bacterial MecA proteins. The development of competence in Bacillus subtilis is regulated by growth conditions and several regulatory genes. In complex media competence development is poor, and there is little or no expression of late competence genes. Mec mutations permit competence development and late competence gene expression in complex media, bypassing the requirements for many of the competence regulatory genes. The mecA gene product acts negatively in the development of competence. Null mutations in mecA allow expression of a late competence gene comG, under conditions where it is not normally expressed, including in complex media and in cells mutant for several competence regulatory genes. Overexpression of MecA inhibits comG transcription.	2.97709e-40
NC_014387.1|WP_013279681.1|369632_370808_+|cell-wall-hydrolase	gnl|CDD|377847	pfam07486, Hydrolase_2, Cell Wall Hydrolase. These enzymes have been implicated in cell wall hydrolysis, most extensively in Bacillus subtilis. For instance Bacillus subtilis steB is expressed during sporulation as an inactive form and then deposited on the cell outer cortex. During germination the the enzyme is activated and hydrolyzes the cortex. A similar role is carried out by the partially redundant Bacillus subtilis CwlJ. It is not clear whether these enzymes are amidases or peptidases.	8.2434e-31
NC_014387.1|WP_013279665.1|346757_347573_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.1369e-26
NC_014387.1|WP_026662903.1|368433_369063_+|uracil-phosphoribosyltransferase	gnl|CDD|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	7.55798e-135
NC_014387.1|WP_026662904.1|367934_368372_+|ribose-5-phosphate-isomerase-B	gnl|CDD|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	3.60219e-75
NC_014387.1|WP_167531130.1|347965_348343_+|ATP-binding-protein	gnl|CDD|379279	pfam13581, HATPase_c_2, Histidine kinase-like ATPase domain.	1.56661e-22

Protein sequences

>NC_014387.1|WP_013279672.1|357808_359152_+|replicative-DNA-helicase
MAEETLLKRVAPNSLEAEQSVVGAMLMDKDAIEIAAEIVTADDFYNRQLGVLFETMVELNREGSAVDIVTLQNRLREKNVPPNVSSVEFIGDLINAVPTSANVKYYAKIVADKSTLRKLIHVSEETINACYNDADDMEGVLNDAEKKVFQITQKRNTGDFVSIDQVVMNALNRIEIASKMKGNVTGHSTGFTDLDYNTAGFQPSDLILIAARPAMGKTAFVLNIAEHMAFHDNKCVAMFSLEMSKEQFVNRLLSMESHVDSQHIRTGNMSDMDWEKLIESADVVGSSKLIIDDTPSISIQELRSKCRKYKMEFDLQVIMIDYLQLMSGGTGRASESRQQEISEISRSLKALARELNVPVIALSQLSRAVEQRPDHRPMLSDLRESGAIEQDADMVMFLYRDDYYNKDTEKKGIAEVIIAKQRHGPIGTVELIWLPQYTKFANLEKGH
>NC_014387.1|WP_013279671.1|357360_357807_+|50S-ribosomal-protein-L9
MQVILLEDVKTLGKKGEIVKVSDGYAKNFVIPKKLGVEATQKALNELKNQQKRDSIIAQQQLDEAKAYGEKISKETIQLTMKAGEGGRVFGSVSTKEIVTAAKQQFGFDIDKKKLQMPEPIKSFGTYEIPVKLHPQVTSTIKVCVKEQ
>NC_014387.1|WP_034475745.1|355305_357357_+|DHH-family-phosphoesterase
MSNKNRVKLKGKLRTYLRVFSYLGILLFLINIAVFTVDFTAGLILLAFTGLYFVVVLYINFYNRPLIMNELVSFATEYGQIQKKLLRELDLAHAVLDDTGKVVWTNQAFERIVHLERGYRKSITTLFPSITPDKFPEGYEELSYEIEYENSNYTMKIKRISLHEMAVNSDIIDAQEYEGSLIAIYLFDETALRLAIEEVDNQSLAAGLIYLDNYEEALDSVEEVRRSLLTALIDRKINKYIASCNGIAKKIEKDKYFVVMPKKSCEMLRDQKFDLLEDVKTVNIGNEMAVTLSIGIGLDGLSYAQNYEFARNAIDLALGRGGDQAVVKSNDNISYYGGKSQQIEKSTRVKARVKAHALREIISGKDTVIVMGHRIGDVDSFGSSVGIYRIAKTLDRKCHIVLNDVTTSMQPLVDLFKNNPDYEEDMIISNQQAIDMAGSNTVLVVVDVNKPSITECPELLRFCKTIVVLDHHRAGTEVIENATLSYVEPYASSACEMVSEILQYIGENVKIKNEEADSLYSGMIVDTNNFMNKTGVRTFEAAAFLRRNGADVTRVRKLFREDALEYKAKADVVSQAQVYKGKFAISVLKNDEIQSPTIIGAQAANELLNIKGVRASFICTEYQNQVYVSARSIDEVNVQVIMEKLGGGGHMSSAGCQIENVNAEQAIEIVKQTLDKMMEEGEL
>NC_014387.1|WP_013279669.1|349768_355177_+|CehA/McbA-family-metallohydrolase
MKNRKRILAFILAGFMSVTTAFQSTSAVVYATEGTEIAVEASSAASSQEDAVVDESLEASEAGSLASSEGTSVEKEVTENPEVTEEALEGAEETKEAEKDVDKAADAQAEVSISTVKEVKEKASGEFTVKGVIVYVNGKNAYLQDDTGAICLYGISELAVGNLVTAKGTYQDYNGLLELSGATLVENDTTNTKDYPFVTFDGDEIATLVANHDDYECQRVILKNVTVGSKADIGKSKVTLTSGSSSVLVFDKSNITKAFGDIEEGTKVNVTAVVSDYKGLQVVLYSDDSHKMVEVVPSEPSEPTDPSVIEIDDSVTLNIASFAGSDVSAFDGDLVVYADGTVANDGANKDHEITAYIGGKQASPVYTYSSSGTSYSIIGSKGMKSGDYYQLTISGKGYGLYKLAFSMKGSNTGAKNWTVSYSTDGENYSNIGDKFTVSANWAEYSFSVPAVVKHVDKLYFRVGPSDNTSIKGAEIGTGGVNRLTPISVTGSPVEAPDITAPAEVEPVAGEIPYDTALTMTCKTEGATIYYSVNGSDFEVYDDANKPVLTQEMFVAASELDVVKKAVVTTYATCDGRKDSVKKDYIYTQAQVATVKASPNGGAVRLNSAVTLATATEGAKIEYSLDNGETWTEYTDPFLLKELPATVLAKANLEGYAESPVATFEFTQRINEEYNIYFGQLHSHTNYSDGAGSCDEAFNHAANEVDNLDFLAVTDHSNSFDNDTSATITDGSASSEWKEGHELADKYTSDDFVGLYGYEMTWSGGAPGHMNTFNTGGFMSRNMTGYESKSRTALQNYYAQLVNTPESISMFNHPGTTFGDFYDFAYYSKANDQQITLIEVGNGEGAIGSAGYFPSYEYYTRALDKGWHIAPANNQDNHKGRWGDANTGRTVILADSLTRENIYDAIRNMRVYATEDNDLHIYYTLNGMEMGTILDEQPSEVNIKVKTSDATDSGRMNVEVIANGGVTVASKTVDEAAAETTFTLEPNFNYYYIRVTQADGNIAVTAPVWLSDVEAVGISSLSTDTALPVAGEALNIKAALYNNEASDFDITSITYTVSGEIVHVTELTDENNKIKSQGELVDSFELVQNDEGMKQIAVTMTGYLNGVSKTYTATLDLVFISPEMVTHVVVDGSHLNDYVNGYYSGNVGNFADIAAGDNVKVDVVTGEITAQTLADASVFVVSAPNKNTKYGEVKHFEDSFIELVKEYVARGGNLIVCGLADYQDTKDGQSSTEINKLLAAIGATTRINSDEIVDNDKNGGQEYRLYFSNFNRDCYLTEGVTSTQTYSAYSGCSVRLDPAAVAAGTAEAVVYGHETTYTKDCKQFDEHYVEVPKGSVVAAARETLSSGSDVLVTGTVFLSNFEVKSELDYGGQEFYANRNILLNYLAQNKKEIKVSTIAEMRQGNPGDIFTVEGYVTAGTAVEGNKFFDTIYVQDDTAGTTVFPVADTGIEVGTKVRLTGFVDGYQGDLEIQIYNYKILDGEKKVIEPAKVTTKEAADYNALGGSLLKVEGKVTKVVTNSSGVDYFYVVDESGVEARVFIDGYILASDGNDTVSEDVKVGNTISAVGLSYYNPDGACLRVRDRAEIELVKTSDEPEAKLVKKYGKYYYMTEDGEKLTGFHAVDGVLRFFNESTGVMAVNKWITVDGKKYRAVEDGRIAANEIIREYGSDYYLGEDGVLVTGIIEYNGNKYCARSNGKIAKSGLLEIDGEYYIPNSDGTLKHDVKTDIYFSEYILGSDCKAVKGFTTYDGQRYYCKSNGRVAKDYMFTVDGYTYYAKKDGTLAVSETITRYFKKYTFDENGHLVK
>NC_014387.1|WP_013279668.1|348481_349648_+|YibE/F-family-protein
MGNVRGTRTLNSKWDFKRIVAIFVLMAIFVVSVCFIRFGLVEKSESSATSHFVRATVSQLIQDNTQKDENTEGILRGSQEVIVQISSGPFKGKKYQTTNYLSALFNINAQEGTRVIVRLDPQSDGYSAFIYSYDRTGILLVMFGVFALSLILIGRSKGAMALVSLIFTLFAIVSILFPLLEYGFPAIPATILIVFYTTVFTFVLIDGINKKTISGALGTLAGVLIASIFAAFAGFISHISGFQTNEAEELLLIGTDHGMKISGLFTAGILIASLGAVMDVAMSIASAVHELHEVNDQMSAMELFRSGMNIGRDAMGTMANTLILAFAGSSFTLLLLIYYYNIGFTQLINTDMVAREVIQGLSGSIGIVLTVPIVAFLSATIETYKRER
>NC_014387.1|WP_167531130.1|347965_348343_+|ATP-binding-protein
MDDLISGNVVDELIHDQIIVAVEEIYVNVAHYAYGQLDENGDSIPDSGTGPVEVIVSDENRVVTITFIDSGIMYNPLEKPDPDVTKPPSERQIGGYGIFMVKKTMDNMTYKYEDDHNILSFSKKY
>NC_014387.1|WP_013279666.1|347609_347906_+|STAS-domain-containing-protein
MTINKTQNGDEVIFALEGKLDTTTAPDLDAALKESFSGAKKMILDFANLQFISSAGLRVILNAQKVMNEKGDLVIKNSGPQILEVFEITGFSDFLKIE
>NC_014387.1|WP_013279665.1|346757_347573_+|alpha/beta-hydrolase
MSWLTLKDGERLFYQDIGSGRKTVVMLHGWASSHEIYSRPVELMKEKARFIIYDLRGHGESKDACKEQVGIETLASDLNELITTLELQDINLFGWSMGGAVALKYIDMYGCDKIKQTIICDMSPKQLNDAEWKLGSKVEDSIIKETGGYEKCDFYTIYKDFSLKSMPELVEVPGKVLDRLIRMRLDECNETVLRSLIKSLDAQDNREVFKKMNVPLVYFYANPGSIFSPKLVNWYRDNSVNEFRAEEFKGNHMFIMDNPDVFAQKLVNVLL
>NC_014387.1|WP_013279664.1|345866_346757_+|alpha/beta-hydrolase
MNSFIYYFSRMIQRKADPILNSITPVIRDDIEAKLNLEYQGDDGNTLKVDIYRGKKHAESGAKLPVMIMVHGGGLYTGNQTIEYNLCQLMAIRGFLVFSISYRLMTDATLMQEIADVAAGFRYVDKHLDNFNGDRGRVNVVAESAGAYLSIYTVAMHRSQALWEKINCRTSTLNVRRMACFSGMYYTDKFDLIGMLYPQQIFKDMRKDKEFMKMMNPEHPEIINNLPPMHLTSSDADFLGKYTLSFADALKKAGIKCKVMFYRGNKELTHAFPAQKSFLPESIEVIDDVTRFFQED
>NC_014387.1|WP_013279663.1|343406_345863_+|alpha/beta-hydrolase-fold-domain-containing-protein
MAGNDKTMAGKIRRGAIRIGLEVIQGLGSSGEQPPEEKAPDNVKEARNFPYINREGIPLAMDIFQPVGPEYDERELPVIVTIHGGGLVTGDRKISLNLSRDLASRGYLVFAIEYRLAPRANVCEQLDDVCAGLDLVGSKLVEYDVDYSRIFLTADSAGAFLAIYTAAMKNSVKLQRVIGHEPSRMVFKALGISCGMFYTNKDDILGALLSEQFYGDRKDDSNFIQYMNPEHPEIVNNLPPTFFVTSRGDFLNQYTISYSKALKRAGKTSKLLYYSEEYLNHTFNFAHPDFPQSKDANTKMLAFFEEQAAIYADRQINSVQKEKEYKELKKSIETGKSGNMKMYKAIKTLNSFDETRLDAPALKCDGKTVSYRQMFRKWDEYAEVFSAINMTGGKKARVIIPGAMTKEAIYSFYALNMTGAVISLYPYRIMGNIEDMLSAIEREKITDVILTDYETSPAYARKLASSKEELGLNNIIILDTQLPESEMSKEELMLTRSNISQLKKVQGVSFMSDLLVKYEASKIVIDDNTSDETLIFHELQAEENKFASLGLAEEALNRIVYELSSLYSKDTSTALAGLSCDLFSRSVLVNQLQLTLFIGNQLVITHKTIYNKDFFKKACGDYVNYLFLREIDMKKIMASAKGLRMNASSIDVLYLFAEKMTKEKTDAIQDFFEMYGGHPQIVVLGNSGSMLVGKRTKPRTVFTLAPLRPIPAAKPMTMPLTPYAPAGLSALSASPRKLPSVGSMPNPLVWKDINGNKHDLSKIVEKIGIIATKMMNKPKKKALNPNEPNGNTDEGLKQLMGILAVMFEPSQTDYYYEE
>NC_014387.1|WP_013279674.1|359885_363416_+|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase
MARNMKTMDGNEAAAYASYAFTEVAAMYPITPSSVMPEHVDEWATAGKKNIFGRTVQITEMQSEAGAAGAVHGSLVVGALTSTYTASQGLLLMIPDIYKVAGERLPGVFNVSARCVASHALNIFGDHSDVYACRQTGAAMLCDSSVQEVMDLTPVAYCAAIEGRIPFINFFDGFRTSHEIQKIEVWDYKDLDEMVNHDAIDAFKASALNPNHPCQMGSAQNPDIFFQTREACNTGYNELPEIVQKYMDKVNAKIGTDYKLFNYYGDPNAEVVIVAMGSVNDTIEETIDYLEKQGKKVGVVKVRLYRPFSAKALVDAIPASVKRIEVLDRTKEPGSYREPLALDVIAALKGTKFESVPVFCGRYGLGSKDTTPAQIVAVFENDKKEEFTIGIEDDVTNLSLDAGAPLVTTPEGTTNCKFWGLGADGTVGANKNSIKIIGDNTDMYAQAYFDYDSKKSGGVTMSHLRFGKKPIKSTYLIKKADFVACHNPSYIRKFNMVQELVDGGSFLLNCPWTVDQLEAEIPGQVKKFMYDHKINFYIMNGSKIGVEVGMGPTRINTILQSAFFNITKIIPEEDAIKFMKDAAQKTYGRKGEDVVKKNWAAIDAGADPKNLIKVEIPESWKDAQDEGLDFKKAEGSRKDVVDFVNNIQTKVNAQEGNTLKVSDVLPYVAGDTPSGSAAFEKRGIAVNVPAWDATTCIGCGFCSLVCPHAAIRTIAMTDDEIAKAPEGLQTKPLVGMDGYKYSVVISALDCTGCGSCANVCPGNNKGETLKMGAIAANKDEQKYFDYAVTLPIKEDVVAKFGEGSIKGSQFKQPLLEFSGACAGCGETPYVKLVTQLFGDRMYVANATGCTSIWGNSSPSTPYTVNAKGQGPAWDNSLFEDNAEFGMGMVLAQNALRDAIKEQVEAVVAAGGAAKDAAQKWLDTFSNGAENSAATDALIEALKGDNSDAAKYIIKNKDFAAKKSQWIFGGDGWAFDIGFGGLDHVLASGKDVNVLVVNTEVYSNTGGQSSKATPTGAVAQFAAGGKEIKQKDLASIAMSYGYVYVAQIAMGANMQQTINAIKEAEAYPGPSLIIAYAPCINQGLKAGMNKVMDEEKKAVATGYWDMFRFNPQAENKFTLDSKPATEDFQSFLDGEVRYLSLKLKNPERAAKLNAAAAEHAKEHRAYLEKLVSLYGKN
>NC_014387.1|WP_013279675.1|363561_364359_-|adaptor-protein-MecA
MKIEKVNDHQIRCTLTKDDLAKRDLKITELAYGTEKAKELFQDMMQQANLQYGFDAEDTPLMIEAIPINSECIVLIITKVEDPEELDTRFSNFAPSVHEEDEEDEYDYDDEDEEYEEDEEEDVMGLFRRLQHSNLSDSLDSSMSSPFSDSKKLKEKTTNPRKKGQPSRKGSRIFSFDSLHEVTRFAAIVSRKFNGINTLYKNETNGKFYLILHQGELEDNVFANICSLLTEYGKTEIGSTAEEQYLAEHYTTLVRDNAVQALSKI
>NC_014387.1|WP_013279676.1|365078_366782_+|SH3-domain-containing-protein
MKKKVIPAIIIIALILVIGGIYAAQIAYQHYSYSDERADLNNYFDISSDTDVAIILGNERIEERARLLDGHYYMDFASVQKYLNDRFYYGEADNSLFYTTASKVIIAEVGSTTWTDSTGTSEDVGYVIARTEGEELYVALDYVKKYTNFFYEGFTEPNHMQLTTSWDDEKIASINKDTQLRLRGGVKSEILIDLAKGDTVTVLEELENWTKVKSSDSYIGYVENKRLSDITTKSPIPVTDYVEEEYTSLNRGHKINLGFHNIGGVAGNDTFSSVVAGAKSLNVISPTWFKLNSNDGDVTSIASASYVRAAHDKGLEVWALFDNFTGTGDFSTTEFLSRYKSRQNAIDQLMALATEMGVDGINLDFETIDYEDGQSYVEFVRELSIACRANGLVYSIDDYVPMHFNDHYNLREQGIVADYVIIMGYDEHYAGSAEAGSVASLSYVENGLINTTAKVDPSKVINAVPFYTRIWHTSGGALSSEAVSMQTAKDYISNHSIELTWDVEAGQNYGEFTSSEGTFNQIWMEDATSIGQKIDSMRAQNIAGIAEWSLGMETPDVWDVIAGYIEE
>NC_014387.1|WP_042256331.1|366786_367845_+|threonylcarbamoyl-AMP-synthase
METEVIVIKESEMNKEAFEGLKRAGQIIRDGGLVAFPTETVYGLGGDALNPMSSKKIYAAKGRPSDNPLIVHVANMDDLAGIVKEVPEAARKLADAFWPGPLTMIMNKNDKVPYETTGGLDTVAIRMPNNKIALELIRQSGGYIAAPSANTSGRPSPTVARYCVEDLSGKIEMIIDGGQVGIGLESTIVDLTSPVPMILRPGYITAQMLKDVLGEISIDKTIIDSKSTERPKAPGMKYKHYAPKGDLMIVQGAQEQVVSYINEQSALAASEGKRVGIIATDTTRELYKADVVKSVGNRQDERTIAHELFKVLREFDDENIDVMFSESFDDSGIGQAIMNRLLKAAGHNIKTV
>NC_014387.1|WP_026662904.1|367934_368372_+|ribose-5-phosphate-isomerase-B
MIALASDHGGFELKESVKRHLDERKIEYKDFGTYDLNSCDYPDFGAAAAKSVAAGECEKGIVICTTGIGISIVANKIKGVRCALCSEVSTARLTREHNDANVLAMGGGFVGPVLANEIVDTFLDTPFSNLEKHSRRIAKIAELEK
>NC_014387.1|WP_026662903.1|368433_369063_+|uracil-phosphoribosyltransferase
MAKVVIMDHPLIQHKIGYIRRTDTGTKDFRDTIAEIATLICYEATRDLQLQDVEIETPICKTTVKELKGRKLCVVPILRAGLGMVDGMLALIPAAKVGHIGLYRDPETLKPVEYYCKMPADVAEREIFVVDPMLATGGSSVAAIQMLKDRGCKHIHFLCIIAAPEGLEAMKAAHPDVDIYVGSLDEKLNEHGYIVPGLGDAGDRIFGTK
>NC_014387.1|WP_026662902.1|369142_369625_+|dCMP-deaminase-family-protein
MKREDYISWDEYFMGVAKLAAMRSKDPNTQVGSCIVSEDNNILSMGYNGFPKGCSDEEFPWERDGEDELGTKYPFVTHSELNAILNYRGGSLVGAKIYVSLFPCNECAKAIIQAGIRTVVYDSDKYSTSASTRASKKMFDAAGVRYYQYQPSGRNIKITI
>NC_014387.1|WP_013279681.1|369632_370808_+|cell-wall-hydrolase
MKKTNWVCGKRIVAILAAVVIGLGSTSSVKVTATESTRKQLEDAKEKKKQSQNDLDNTKDDIAEMNEEKSSLQNQLSSLNNQLTEVSNNLEDLEEQIDDKEIEIENTMAELEAARKTEVSQYASMKKRVQFIYEKQNFVLFDMLVGATSFANFLNQNNYVEQLSAYDRKMFLQYIETRKSIEAKEAKLKEEKEQLDEYKVKAQAEQSRVSGLVNQTSGSIKQYANDISDAEAKAQALEDQIKAQEADIKKLEAKLAEEIRLSKLAASSAWRNISEVSFADGDRYLLANLIYCEAGSEPYEGKVAVGAVVINRVLSSVYPDTVVGVIYQNKQFSPVSSGRLALALAEGKATAACYQAADEAMKGYSNVGNCVYFRTPVPGLSGINIGGHVFY
>NC_014387.1|WP_013279682.1|370801_371293_-|DUF402-domain-containing-protein
MDHPILYRKRFIPDECLELKDDIILECNGKQIVTKWNTIHSRCDLARGYSCYYLDRGYKISKFLRSDDSLLCWYCDIITYEYNPDKNSLLVIDLLADVKIYPDGRQRVVDLDELSEAFEKRLIDETLLKKSLLSLNKLLNDLYEVGIIELASPIEKLADKNDQ
>NC_014387.1|WP_143754242.1|371484_373938_+|hypothetical-protein
MTAQMSEATLPTVSFVSNYREVSPLHGYLEEMDISHIRGTIFPIGSGRDINYKIKTYGQKVTNLSFEVRNIDGSGLVENTDLQDYKESEDTITGSFQLKDLISSGSEYMLVMLMDTEIGRARFYSRIVWTNDESRYHIDEEVDFVRNFSIATFDKEAASEYSRYLESNSEGDNTSFNKVNIHSSFNQVTWGDLQIVDHSDPEVYVTDIHGQTGSYLLKYQISIKEGALNKTYNVCEAYRLRFTSDRIYLLNFERTVNYIFDTKSFSITKNVIGLSISDPDLQLVESSSGSAFAFVSENRLYMLNNSENRLAYLFGFYDDNNNDIRTRWDQNCIKILKVDEAGNVKFAVAGYMNRGTHEGQVGIAVYDYNATINAVEEQAFVQSKSDPQILMEYVDTIAYVNNSDVFYVMLDQNIYAIDLNDRTSTSVVDDIGQGEYKISESMNTIAWQSDDLKSLNMMNLGTKTVSEVTAENGDLIRVLGFMGEDMVYGLVHESDVLNDQMGNPVYAMYNILIQDGDGNILENYHPDGIYVTSVSISDNQIRMTRVVKDEEAGKYISTYDDQIMSTLKAEKGSNTVSVVSVDIYEKIVQISTKSEIKTKQIRVLTPAQTLFEGDRDVNIDTKRNADEKPFYYVYGLMGIEGIYSDPAEAVKLAFRSPGTVVGDNNKYVWIKGNLLRSNQNMSITRSAEIYPNMTSKDPVSVCLDLILNYEGVNRNVESLLAGGDSVYQILESSLPDARILDLDGCPMSAMLYYTNKDIPVMAMLNDGTAVLIIGFNDLNTVLMNPTTGAVYKYGMNDSEKLFEENGNHFITYIMEED

Crispr_ID: NC_014387_3

• CRISPR_ID: NC_014387_3
• CRISPR_location: 785462-785544
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014387_3

Consensus_repeat	Method
GCAGGAGATGCTAAGCCTGAGGAGAAGCC	CRISPRCasFinder

spacers of NC_014387_3

>3.1|785491|25|NC_014387|CRISPRCasFinder
TGCGGCTTGCGGAAGCGCTTGCGGG

CRISPR arrays and Neighbor proteins around NC_014387_3

CRISPR arrays

The CRISPR arrays of NC_014387_3

>merge|NC_014387|3|785462-785544|CRISPRCasFinder
GCAGGAGATGCTAAGCCTGAGGAGAAGCCTGCGGCTTGCGGAAGCGCTTGCGGGGCAGGAGATGCTAAGCCTGAAGAGAAGCC

>NC_014387|3|3|785462-785544|CRISPRCasFinder
GCAGGAGATGCTAAGCCTGAGGAGAAGCC	TGCGGCTTGCGGAAGCGCTTGCGGG
GCAGGAGATGCTAAGCCTGAAGAGAAGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014387.1|WP_013280042.1|784843_785170_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NC_014387.1|WP_174261974.1|776122_776902_+|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl|CDD|234577
NC_014387.1|WP_042257490.1|791340_792969_+|IS1182-family-transposase	unknown	unknown	gnl|CDD|372705
NC_014387.1|WP_042257485.1|786782_787736_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176205
NC_014387.1|WP_013280040.1|782013_783132_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NC_014387.1|WP_013279565.1|788114_788585_+|IS200/IS605-family-transposase	unknown	unknown	gnl|CDD|376616
NC_014387.1|WP_013280046.1|788840_790235_+|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|225420
NC_014387.1|WP_013280039.1|780391_781366_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|316042
NC_014387.1|WP_013280033.1|777219_777648_+|50S-ribosomal-protein-L13	unknown	unknown	gnl|CDD|181703
NC_014387.1|WP_013280038.1|780024_780261_+|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_042256446.1|795082_795415_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NC_014387.1|WP_013280050.1|794417_795050_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|238045
NC_014387.1|WP_042256441.1|777674_778073_+|30S-ribosomal-protein-S9	unknown	unknown	gnl|CDD|178888
NC_014387.1|WP_013280041.1|783562_784642_+|plasmid-recombination-protein	unknown	unknown	gnl|CDD|366451
NC_014387.1|WP_013280049.1|793266_794088_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|225117
NC_014387.1|WP_013280047.1|790262_790760_+|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_013280052.1|795831_796347_+|DUF2441-domain-containing-protein	unknown	unknown	gnl|CDD|287372
NC_014387.1|WP_013280037.1|779337_779862_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_014387.1|WP_013280044.1|785693_786746_+|radical-SAM/SPASM-domain-protein,-ACGX-system	unknown	unknown	gnl|CDD|213953
NC_014387.1|WP_167531139.1|781473_781626_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014387.1|WP_013280042.1|784843_785170_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	4.04963e-41
NC_014387.1|WP_174261974.1|776122_776902_+|tRNA-pseudouridine(38-40)-synthase-TruA	gnl|CDD|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	8.13625e-123
NC_014387.1|WP_042257485.1|786782_787736_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176205	cd08243, quinone_oxidoreductase_like_1, Quinone oxidoreductase (QOR). NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit.	1.58732e-132
NC_014387.1|WP_013280040.1|782013_783132_-|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	7.5005e-21
NC_014387.1|WP_042257490.1|791340_792969_+|IS1182-family-transposase	gnl|CDD|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	5.1356e-30
NC_014387.1|WP_013280046.1|788840_790235_+|putative-DNA-binding-domain-containing-protein	gnl|CDD|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	2.51832e-85
NC_014387.1|WP_013280039.1|780391_781366_+|AAA-family-ATPase	gnl|CDD|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	2.64557e-22
NC_014387.1|WP_013280033.1|777219_777648_+|50S-ribosomal-protein-L13	gnl|CDD|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	3.04511e-94
NC_014387.1|WP_042256446.1|795082_795415_+|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	4.95062e-09
NC_014387.1|WP_013280050.1|794417_795050_+|tetratricopeptide-repeat-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.2217e-13
NC_014387.1|WP_042256441.1|777674_778073_+|30S-ribosomal-protein-S9	gnl|CDD|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.41366e-81
NC_014387.1|WP_013280041.1|783562_784642_+|plasmid-recombination-protein	gnl|CDD|366451	pfam01076, Mob_Pre, Plasmid recombination enzyme. With some plasmids, recombination can occur in a site specific manner that is independent of RecA. In such cases, the recombination event requires another protein called Pre. Pre is a plasmid recombination enzyme. This protein is also known as Mob (conjugative mobilisation).	7.12246e-10
NC_014387.1|WP_013280049.1|793266_794088_+|helix-turn-helix-domain-containing-protein	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.12284e-20
NC_014387.1|WP_013280052.1|795831_796347_+|DUF2441-domain-containing-protein	gnl|CDD|287372	pfam10386, DUF2441, Protein of unknown function (DUF2441). This is a family of highly conserved, predicted, proteins from Bacillus species. The structure forms a homo-dimer. The function is unknown.	6.09499e-13
NC_014387.1|WP_013280037.1|779337_779862_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.38311e-16
NC_014387.1|WP_013280044.1|785693_786746_+|radical-SAM/SPASM-domain-protein,-ACGX-system	gnl|CDD|213953	TIGR04340, radical_SAM_domain_protein, radical SAM/SPASM domain protein, ACGX system. Members of this protein family are radical SAM/SPASM domain proteins likely to be involved in the modification of small, Cys-rich peptides. Members of the family of proposed target sequences, TIGR04341, average 75 amino acids in length and average six instances of the motif ACGX, where X is A, S, or T.	0
NC_014387.1|WP_013279565.1|788114_788585_+|IS200/IS605-family-transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.45631e-46

Protein sequences

>NC_014387.1|WP_013280042.1|784843_785170_-|helix-turn-helix-transcriptional-regulator
MKTKDELPECPVATTVSLIGSKWKLLIMRNLLVRPWRFNELKNSLEGISQKVLTDSLRSMEEDGIITRTVYPEVPPRVEYALSDLGESMRPIISSMESWGKDYKKSLE
>NC_014387.1|WP_013280041.1|783562_784642_+|plasmid-recombination-protein
MITVTFHISCKKHSLTKTRDVVSVSKHNLRLFQSEEYNEEMIEVEVGSEVNILDDVKEIYEREFSEVLAEYNKGKRSDRQIHDYLEYVSESKKNDVATEVILQVGDKEFWADKTREQWNAMKPLLREQLEYVKEIVPEFKIASAVTHLDEDSPHMHVVGVPVATGYKRGLSKQVAKTKVFDQKRLETIQDQMHDFVEQQMKDHPEIFGDETLKPKEKGRNSDFSKEFYLRLKQQEYEKLEDKCQEKETQIEALDDTAKEMKQDIESKVDQYVDSVVNSEMKKEFMRYATLENPKTTLGKIVSKAFKTFKEWWDKTKKPEIAEKAKTSILQKLRESQAIVDQRKEQQVPNLNRNNLMSER
>NC_014387.1|WP_013280040.1|782013_783132_-|IS110-family-transposase
MNNITVYVGMDVHKESFTLCDYLIETEKASHTRRTHADYKEVLKYLEFLRTIYGNDTNFICGYEAGCLGYTLYHQLTNHNVNCVILAPTTMLEPRSGKRIKTDKRDAELIGKCLAQHNYSPVHVPTSTDEETKEFLRMRDDHKLALKKVKQQILSFCLRHDYRYEGKSHWTEAHVNWLKSLKPEALYKEILDEYLLTYINLRDKLERLDKRIEELALKDEYREPVKKLCCFIGVQTHTALSVLVEVGDFKRFASANQFAAYLGLVPGEESSGDEKSRLGITKAGNRHVRQLLIESSQSYSKGQIGHKSKALKSRQIGNSPQVIAYADKANERLRRKFYKMVLGKSKKHNVAKTAIARELACFMWGMITDNIA
>NC_014387.1|WP_167531139.1|781473_781626_+|hypothetical-protein
MKNVQISQELFIRLVRLLVFEFDEDTDLIKKELEDKMEKLICNDLLSSKK
>NC_014387.1|WP_013280039.1|780391_781366_+|AAA-family-ATPase
METSKPELKLIQMSDVEAEEVSWLWYPFIPYGKLTIIQGDPGDGKTTFVLNASAKLSKGISLDTGLQSEEPINIIYQTAEDGLADTVKPRLEGAGADCSKIHVIDESDKSLSMVDERVEQAIIRTGAKLLIMDPLQAYLGGGMDMNRANEARDMTKKLGALAEKYKCAIILIGHMNKASGNKAAYRGMGSIDFYAVARSVLLVGRIEGEPELRAIVQIKNNLAAFGHSKAFRLSEKGFEWIGDYEITADEVLGGIAPKANKQEKAIALLRELAEDHNMILSNEAVELAKEEDISKRTLEIAKNELGIKARRINNTWYWILKENE
>NC_014387.1|WP_013280038.1|780024_780261_+|hypothetical-protein
MEDKKLYVELPRFTGRNVPITEVAEAMHKDAQFVRIGIQQGIFKFGYAMKKENSSEYNYYCPDRKVWEEIGYFSPEAV
>NC_014387.1|WP_013280037.1|779337_779862_-|helix-turn-helix-transcriptional-regulator
MNNGSDIGNRIKEARKAQHLSQTELANRLGKTMRTVQKYESGEIEPSIGVLNEIANNLNISPAELIGYQKKNITLNTLSDVLYVLNELNKKAGLHFNIDVNRPPKTEEWSCSLKFMGNDEIAENNADLCLFLERYADERESLEQGLSNKDRFNHWFETELAYYANVALPDKKGD
>NC_014387.1|WP_042256441.1|777674_778073_+|30S-ribosomal-protein-S9
MAKSASYYGTGRRKKSIARVYLVSGNGNITINKRPIDEYFGLETLKVIVRQPLVATETADKFDVVVTVRGGGTTGQAGAIRHGISRALLQADSDEYRPTLKKAGYLTRDPRMKERKKYGLKKARRAPQFSKR
>NC_014387.1|WP_013280033.1|777219_777648_+|50S-ribosomal-protein-L13
MKTYMPSATTVEKKWYVVDATDMTLGRLASNVANVLRGKNKPIYTPNIDTGDYVIVINAEKIKVSGKKLDQKMYWHHTDYVGHHKEFSLRQMLQDKPERVIEHAVKGMLPKGSLGREMYTKLHVYAGAEHPHAAQKPEVLTF
>NC_014387.1|WP_174261974.1|776122_776902_+|tRNA-pseudouridine(38-40)-synthase-TruA
MRRIMLTVSYDGTAYNGWAEQTSTPNTIEGELNRAIERLTGEPVHVIGASRTDAGVHAYGNVAVFDTASSIPGDRFVFALNHELPQDIRIVNSREVATSFHPRHCDTEKTYEYRIFNSQIMDPTKRFYTCHFSMPLDIGRMNAAAHYLVGEHDFTSFCNVESQALSHVRTIKDIRVTRNGDEVVISVTGNGFLYNMVRIIAGTLMQIGRGKGTPAEVKDILDKKYRGAAGPTAPAEGLFLVEYKFLDGIPGPDTDCKSN
>NC_014387.1|WP_013280044.1|785693_786746_+|radical-SAM/SPASM-domain-protein,-ACGX-system
MKPYFSFQWHITDECDQRCKHCYIYSSGEHTCLFSMNWKQMEDTFYNCLDFCEVYGRTPYFYITGGDPILHPDFWRLLQLMKDHDIKFTILGNPFHLNDQVCRELKWYGCEKYQLSIDGLRETHDWFRKTGSYDCTLEKIGCINRAGIRSVIMTTVSKTNRMEVPGIIDAVVAAGANVFAFARYVPSGGDLDASMTATEYRELLAACDKKFKEYKAEGCETYFNKKDHLWILYEYEIGDFKIPENVDPNMIYGGCNCANCHMTILPTGDIYACRRVADSKVGNVFEDRIADLWETSFEDYREYDKLEKCSKCKLKAWCRGCPAVACGTNGSFYSDDPQCWADVNSDLFVS
>NC_014387.1|WP_042257485.1|786782_787736_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKAVVLDGPTNVEDIFLKEKEVPVVVPGWVLVKVKAFGMNHSELILRHEEIKYDYIKKPIIPGIECVGEIADPSNSSFKAGDKVIAMMGGMGRSFDGSYAEYALLPAHHVFKIESNLKWSELAAIPETYFTAWGSLFECLQLRKEDTLLIRGASCALGLAAIQIAKTLGCKVIATTHKEKYLDLLMSADERIVDDGKLTGKVKGVTKALDLVGPKFLLDTMASVEKGAIVCQTGILGGVYALNGFDPIKHIPNGVYLTGFYSNFPTQGIVDDMFSFFNKHDLKPIHGPVYTFGKIKDAMLMQESGKAGGKIIVFIER
>NC_014387.1|WP_013279565.1|788114_788585_+|IS200/IS605-family-transposase
MDMNSLSHTKWECKYHIVFAPKFRRKVAYGQIKQDIANILSTLCKRKGVEIIEAEVCPDHIHMLVRIPPSMSVSSFVGYLKGKSTLMIFERHANLKYKYGNRHFWCRGYYVDTVGKNAKKIEEYIKNQLKEDLEYDQMTLKEYIDPFTGEPVKQNK
>NC_014387.1|WP_013280046.1|788840_790235_+|putative-DNA-binding-domain-containing-protein
MRDIDKIIEDDENQVVEWKESWQDKYLEWICGYANAQGGTLYIGVDDNGNVIGLDSKVQKKLLEDIPNKITAAFGITCDVNLKSKDKKKYIQVEVKKSRLPLNLHGRYYYRTGSVKKEITGFELTEFIIKSTGTSYDAMVSDITRDKLTFEAFKKRYLDVLSGNHDFEEDLISFRLMQEDGQMTNAGVLFADQWNIHHSRMFCTRWNGLDKAGSVQDALDDLEITGSLLSLFDNAMDFVRKNSKKGWRKDKDKRVELPDYPERAVEEGLVNALIHRSYLQTGAHSQIDIYDDRMVITNPGGMYDGSEVQLLDLRHVPSKLRNPILADVFGRLRLMERRGSGFKKILDAYESEERYTDSLKPEFYTDGYNFFLTLWNLNYAYDKAQNKAQIKAQIKAQIKAQRGTLSDRDYILLLIKENPTITQEELANIMGKSRRSVQMLMKQLIEDDAIERLGSKKQGTWILK
>NC_014387.1|WP_013280047.1|790262_790760_+|hypothetical-protein
MRTIDIINIIAIIVSPVVAVVVGQILQDRRKKRSDKMEIFKTLMISRGLGWSTESVKALNIIEVVFSDDQSVLNQWKIYYDRLCVENPNEMELSKIKTEGDKLLDVMAKSLGYKEKVTWETIQKPYIPKGLSDNIIQQQQYQSAQLDIMNAASIYFQQMKNESQK
>NC_014387.1|WP_042257490.1|791340_792969_+|IS1182-family-transposase
MRLNKILQGDYTVSSLHHQIKLPLDIEISIPSDDPVRLLSAFVEEMNLSDLYKTYDRIRKGQASPRQMLKIVIYAAMNRIYSSRDIESACKRDINFMYLLDGAPAPDHSTIARFISMHLSQCAKQIIAQVGTILLELGEISGENIFIDGTKIESVANKYTFVWKKAVSKNMIKLTEKICVFCAGCEELYGIKVVYNDQISLHTLKRLRKKLYKLKEDEGIEFVHGIGKRKTQLQRSLEALEEYIEKLKEYNHKLYVCGTRNSYSKTDTDATFMRMKEDAMLNGQLKPAYNLQHGVDSEYVTWLDVFPAPTDTITLIPFLKDMESHLTFKYKNIVADAGYESEENYIFIESNEQAAYIKPQNYELSKTRKFRNDISRRENMDYDPESDCYTCRNGQQLPAVSKRTQKSATGYQREVTIYECSSCNNCPYKKDCIKGNNCKTAFEDRNKKLSVSRKMEEKRAECLERITSDYGTQLRMNRSIQAEGSFANVKEDMNFRRYLYRGKENVLTQSILLAIGYDINKLHHKIADERTGTHLFELKKVS
>NC_014387.1|WP_013280049.1|793266_794088_+|helix-turn-helix-domain-containing-protein
MENFQLLIEAMEYIEDNLTEPIKTENIADKLHCSKSTIEKLFRYINNISIRDYIIRRRMSKVSREIVSNPEKSLLDIAVEYGYGSNEAFSRAFCSVWQVSPSEFRKNPSKFELFPGYRIDQELMEEKTMDDRKKIDISELYDCIRERKGCYLVLGDIKSLIPINEISHKAGDLAIITAMKRMEQAAGAEDIVFRIGGDEFVILTNSKEENYSNSICEEIISHNDEPIFWEKKEIPLSLYVKVICYEGRTALRYSEFFTMLQNELSEEYKRQYF
>NC_014387.1|WP_013280050.1|794417_795050_+|tetratricopeptide-repeat-protein
MNYLPANLKKYRIQKDLTQEDVAEFLGITAQSVSKWERGESYPDITLLPALANIFETSVDLLLGMDTIRAEQTRLDIHKKAISFQRSGNYDMAEKTYREALLIYPNKPGMILGLASTLALKGETEEAIELMERGLPISINEKQKATMRATLCFLYLKSGREDKANKLASQLPHMRESREVIQPLIQQGLRNSEIDENIKNIVLGDGEGIW
>NC_014387.1|WP_042256446.1|795082_795415_+|GNAT-family-N-acetyltransferase
MLIRNGHEADICEILQMIKDSYTPYDDLICDISIPTYTREEIHSLLNEPQSDVWVVEDNGNIVGMAAGTEFGPCAYHLKMLFVLGKSQYQGIGRELLKKEHEKDAFLYLQ
>NC_014387.1|WP_013280052.1|795831_796347_+|DUF2441-domain-containing-protein
MPKKAGEHIVLDKSHPNGVHKRVYDHIKTVEDIYNNPDKYKDVELDYSVMVALRELALEKVRKQKYPQYPSRMASIYVSKSFKEAEQWGDYFAKLGRPTYGIAKINVNGNTYEGDAYKCFDGCVSEEENLKMAEAYWSNGENADGHRVILEILADGDIEVVEIVKEINANI

Crispr_ID: NC_014387_4

• CRISPR_ID: NC_014387_4
• CRISPR_location: 1123903-1123993
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014387_4

Consensus_repeat	Method
TGATACATCTGCGTATGAGGATTCA	CRISPRCasFinder

spacers of NC_014387_4

>4.1|1123928|41|NC_014387|CRISPRCasFinder
GCTGCACTTATTTCATCTGATGCTGAATCTGAGGAGATGGA

CRISPR arrays and Neighbor proteins around NC_014387_4

CRISPR arrays

The CRISPR arrays of NC_014387_4

>merge|NC_014387|4|1123903-1123993|CRISPRCasFinder
TGATACATCTGCGTATGAGGATTCAGCTGCACTTATTTCATCTGATGCTGAATCTGAGGAGATGGATGATGCATCTGCGTATGAGGATTCA

>NC_014387|4|4|1123903-1123993|CRISPRCasFinder
TGATACATCTGCGTATGAGGATTCA	GCTGCACTTATTTCATCTGATGCTGAATCTGAGGAGATGGA
TGATGCATCTGCGTATGAGGATTCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014387.1|WP_013280318.1|1129050_1130829_+|DNA-primase	unknown	unknown	gnl|CDD|235551
NC_014387.1|WP_013280307.1|1113667_1114870_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_014387.1|WP_143754332.1|1139766_1140219_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|181835
NC_014387.1|WP_042256562.1|1137883_1139575_+|von-Willebrand-factor-type-A-domain-containing-protein	unknown	unknown	gnl|CDD|378796
NC_014387.1|WP_013280310.1|1117404_1119165_+|glycoside-hydrolase-family-3-protein	unknown	unknown	gnl|CDD|224389
NC_014387.1|WP_013280321.1|1133345_1134998_+|nucleoside-kinase	unknown	unknown	gnl|CDD|238986
NC_014387.1|WP_013280305.1|1111148_1112648_+|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NC_014387.1|WP_026663497.1|1131207_1132422_+|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl|CDD|236413
NC_014387.1|WP_143754331.1|1112780_1113638_+|inner-membrane-translocator	unknown	unknown	gnl|CDD|119321
NC_014387.1|WP_081441803.1|1132491_1133277_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|378972
NC_014387.1|WP_013280314.1|1123145_1123613_+|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_042256560.1|1128040_1129048_+|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl|CDD|234934
NC_014387.1|WP_013280309.1|1115862_1117404_+|family-78-glycoside-hydrolase-catalytic-domain	unknown	unknown	gnl|CDD|379971
NC_014387.1|WP_013280322.1|1135088_1137650_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|225110
NC_014387.1|WP_013280316.1|1127609_1127912_+|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_013280308.1|1114886_1115870_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|119321
NC_014387.1|WP_013280313.1|1121573_1122932_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240542
NC_014387.1|WP_013280312.1|1119902_1121411_+|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NC_014387.1|WP_174261975.1|1119189_1119822_+|beta-phosphoglucomutase	unknown	unknown	gnl|CDD|213672
NC_014387.1|WP_042256566.1|1140211_1141006_+|DUF4367-domain-containing-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014387.1|WP_013280318.1|1129050_1130829_+|DNA-primase	gnl|CDD|235551	PRK05667, dnaG, DNA primase; Validated.	0
NC_014387.1|WP_013280307.1|1113667_1114870_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.86313e-06
NC_014387.1|WP_143754332.1|1139766_1140219_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|181835	PRK09415, PRK09415, RNA polymerase factor sigma C; Reviewed.	4.24201e-31
NC_014387.1|WP_042256562.1|1137883_1139575_+|von-Willebrand-factor-type-A-domain-containing-protein	gnl|CDD|378796	pfam12034, DUF3520, Domain of unknown function (DUF3520). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 180 amino acids in length. This domain is found associated with pfam00092.	1.07513e-80
NC_014387.1|WP_013280310.1|1117404_1119165_+|glycoside-hydrolase-family-3-protein	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	4.46918e-63
NC_014387.1|WP_013280321.1|1133345_1134998_+|nucleoside-kinase	gnl|CDD|238986	cd02028, UMPK_like, Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK).	1.13851e-66
NC_014387.1|WP_013280305.1|1111148_1112648_+|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	4.54567e-173
NC_014387.1|WP_026663497.1|1131207_1132422_+|RNA-polymerase-sigma-factor-RpoD	gnl|CDD|236413	PRK09210, PRK09210, RNA polymerase sigma factor RpoD; Validated.	0
NC_014387.1|WP_143754331.1|1112780_1113638_+|inner-membrane-translocator	gnl|CDD|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	4.77844e-27
NC_014387.1|WP_081441803.1|1132491_1133277_+|SAM-dependent-methyltransferase	gnl|CDD|378972	pfam12847, Methyltransf_18, Methyltransferase domain. Protein in this family function as methyltransferases.	3.48718e-67
NC_014387.1|WP_042256560.1|1128040_1129048_+|deoxyguanosinetriphosphate-triphosphohydrolase	gnl|CDD|234934	PRK01286, PRK01286, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NC_014387.1|WP_013280309.1|1115862_1117404_+|family-78-glycoside-hydrolase-catalytic-domain	gnl|CDD|379971	pfam17389, Bac_rhamnosid6H, Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants. Some rhamnosides are important bioactive compounds. For example, terpenyl glycosides, the glycosidic precursor of aromatic terpenoids, act as important flavouring substances in grapes. Other rhamnosides act as cytotoxic rhamnosylated terpenoids, as signal substances in plants or play a role in the antigenicity of pathogenic bacteria.	1.00765e-18
NC_014387.1|WP_013280322.1|1135088_1137650_-|GGDEF-domain-containing-protein	gnl|CDD|225110	COG2200, Rtn, c-di-GMP phosphodiesterase class I (EAL domain) [Signal transduction mechanisms].	4.32456e-58
NC_014387.1|WP_013280308.1|1114886_1115870_+|sugar-ABC-transporter-permease	gnl|CDD|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	4.14709e-22
NC_014387.1|WP_013280313.1|1121573_1122932_+|MATE-family-efflux-transporter	gnl|CDD|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	3.64865e-102
NC_014387.1|WP_013280312.1|1119902_1121411_+|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	9.58543e-34
NC_014387.1|WP_174261975.1|1119189_1119822_+|beta-phosphoglucomutase	gnl|CDD|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	7.20322e-82

Protein sequences

>NC_014387.1|WP_013280314.1|1123145_1123613_+|hypothetical-protein
MEKNFSSENENAVKENEICKEGQESAAVSAGALEELIKLNRKQLFYRRIGTWCLAGILVVVAIAVIILIPKVTITLDHINSVAVKAEESLANVDTMAADVSNSAANFDKLLAENSKELTESIKEISEIDFDGLNKAIKDLQDAVGPMASFMNKFR
>NC_014387.1|WP_013280313.1|1121573_1122932_+|MATE-family-efflux-transporter
MKDYLLPIRTGQKLTVREEIILILRLSLPAILAQISSIIMQYIDASMVGHLGANASASIGLVSSSTWLVGGIITAASMGFSVCVAHRIGAQDERGARVIVRWGLICNFFFSLLIMAACVMVSPMLPMWMGGDAAIRKDATAYFLVYAFSVPVREMFLTSQGMIQSSGNIRLPSILNVIMCALDVVFNALLIPHFGVMGAALGTAFSFVVIMIVMMYELLVKSPALYIIGRSGDGNTSLFAFLSKELLTALKIAIPVAIDNVIMGFAYVAFTRIVSPFGTVSVAANSFSITAESLCYMPGFGIGVAATTIVGQCIGANRKTLARRLGWMSVILGMVIMGCSGILMWIFAPWMIGILSPDQEIRMLGTRILRIEAFAEPLYGASIVAAGVFRGAGETLLSSVLNLLSVWAVRIPLAYYLGSMFGLRGAWIAMATELCVRGTLFLIRLALWNRNK
>NC_014387.1|WP_013280312.1|1119902_1121411_+|diguanylate-cyclase
MIKKFFFPSIDKDVLEIMDKISTKGIENISLIVAIFEAITLAIFVLTRKSFGSEEWKSITSVLFCVATCTCGYFSAKYILREKKLKHILVTMLNAIYLMLMSLWGMWASYRRYGRGEQILTFYAVEVMVVCFIALKPWVSTALTISSYIILYLVLYLVDGAAGINIINYSILALVSAIGMGVRYHTLIRASQATVELQKTKDSEIQDKINMLQAIANIYDKVNLIDFVNNYEMSVRSKEQIKHDIDPVSQTHTVMSRMIRKRLMPDQLDSFIEYTNLKTVRSRLAGKRLLSDDFIDVVDGWFRAQYIPVEVDENGIPSRIVFTTRNVDDEKKREERLVRIAMTDELTRLFNRRSYEEDLASYRENGLDKDFIILSADVNGLKKVNDTIGHAAGDELIKGAADCLVLAIGNKGKVYRTGGDEFIALIHADNPQKICADIESCVNEWHGKFSESLTISIGVAAYADNQDLNVNELEKKADNEMYQAKARYYAAKGVDRRASGKR
>NC_014387.1|WP_174261975.1|1119189_1119822_+|beta-phosphoglucomutase
MNIKGIIFDLDGVICSTDEYHYQAWKSIADDEGIYFDRKINERLRGVSRAESLEIILERAAAVYSPEEKAALMEKKNNIYRELLKNMGPGDVTEEVRSTLRELKERGYGLAIGSSSKNTRFILERTALTDAFDGISDGNMISRSKPDPEVFIKAAGILGLKNEECFVIEDAISGINAANAAGFHSVGIGPAAECDEAEFKISFFSEILDI
>NC_014387.1|WP_013280310.1|1117404_1119165_+|glycoside-hydrolase-family-3-protein
MSIKIDYKANPFCLDDEAIKWVEDTFASMTEDEKCGQVFCPMGFSNDDNVLRGIVEGAAVGGMMYRSGPAKELRATHRKIQDMARIPLLIAANTEAGGDGLSFEGTSFGKPMAVAATNDPENGYRMGYVACKEGAALGLNWSFAPIVDINREFHNPITNVRTFGDDPKKIEAFASRYMDGADECGVAVSIKHFPGDGIDERDQHIVTSVNSLGVREWDESFGYIYGSLIGKGAKTVMVGHIAQPAYVKEINRDATKEEMLRPASLSKELLQGLLRGKLGFNGLIITDATPMVGFTSAMPRSRAIPTAIMSGCDMILFNKDLSEDIGFLKDGLKSGLLTNERLDEAVLRILATKASLGLHVKQREGRLVPPEDAIDIVGCSEHRAFAKEVADKAITLVRDEKALLPVNPGKYKRIYLNVIDKEMDPCSDFALMWKEKLEKEGFEVTVRDRRTRITPMDFMDVENLPDKKKALLNEMYRSVSEMKKDYDLYIYVCNMENASNNTTLRLNWNVLFGLGDDAPWHAKEIPMIMVSTAYPYHLFDAPMIGTYINAYSGNEDFCNAVIEKLMGRSKFEGVSPIDPFCGKDYI
>NC_014387.1|WP_013280309.1|1115862_1117404_+|family-78-glycoside-hydrolase-catalytic-domain
MYNEKLLREATALFPEIKKNKINECKCIDLKKDGDVIKRDPRPAYESIALKKDDSIILDFEDHYVGYLSLDLGYEGAHPDSPVLLRIRFAEREIELFEDASEYKGWVSPAWIEEEIIHVDIVPSVVKLDRRYSFRYVRIEVVDISSRFSLRVNDASLTAVSSAPDEALLPYYSSNELDREIDRVAVKTLHDCMQTVFEDGPKRDRRLWIGDLRIQALVNYVTYNMNDMVKSNLYLFGALTQEDGRVGACIFLDPKPEVDDTNMFDYSLFFIVILRDYYKRTGDKKAVLDLFDVCKRQIQLASNSLDERHVVRDSDVLGWCFVDWNLALNKQASAQGIFMYALEAAIELAQCVGDVLAEEEYAQLYLKLKEASNRFLYDVEKKLYVSGAESQISFASQIWMVLGGAMEGKAAERLFDRMEACPEAVTMVTPYMYHNYIDALIKIGKKDVAHRKMSKYWGGMVANSADTFWELYNPEKPNESPYGGTIVNSYCHAWSCGPAYFLRTYFNDTKDES
>NC_014387.1|WP_013280308.1|1114886_1115870_+|sugar-ABC-transporter-permease
MSTLKKILKTLAIPAAVAVVLEGICLANGQTIISGAKSFDNFVVYTAIVMITTMALSINLNSGRFDFSLGAMAGLSSVIGAKITYGFLKGGSGSALLMLIITVLAGALLGLISGAVYCALRLPPIIVSLGVTLVYEGIMYTITGGKYLMSEVQNRSMSGFVGTWLYAAVIIAAVLIFMIIVFERTSFGYDYNALKSGQKVAVATGINEVKNALICYTICGGLMGLVGMLNAARNTTINGGQLNFGSIAIMFTAFLPMFIAGYIGRFGNEKVGFLLSALCMSLLNSTFAVFSNRINATTQSIINAVLLVIFLIYLNNNHLIKRIFAHV
>NC_014387.1|WP_013280307.1|1113667_1114870_+|LacI-family-DNA-binding-transcriptional-regulator
MNRKVTKVLGLAMAAAMTVMTGCGNSAPAAASDTTDNSTDNAVVSEASADQGETRKIGVLVADVSGEEALGFRNYYEKYIQNNYNVTFDYTDALASAEDEKAAIEKFASKGYDAVISLSSSDRAQQIETCEEYGVYYAVASGVLDESQYETYKTYEHFAGQVGPSNETEFEAGKEMGKYFKDKGVKSVAIYGAFIPNPMHVYRAAGVIAGLGDTYGGTDDMNGMIGQIFQDQGVDLTKVSGDVEVVAYLQGYGDTTTDELNAAIQKAPEAFISVGMATTFFAQTLSQENIPFSDIDSFTAMNSESMKNGSLEYLAGKYSSSIGPVFALVMDAINGNVIRDPEGNAVSFTQSYLVATDAESFDQYYVNDNGDTPIFDKASLDGIIGQDVTYDDVKALIESK
>NC_014387.1|WP_143754331.1|1112780_1113638_+|inner-membrane-translocator
MYLKIVFNEALVLAIVATGATFIYTLGTFDISLGASTLFSATLGVMAYNRTENIALMMAVILLTGIVCSLLNSVLASIFHIPAFVTTVAMMSVLSAVSAQIITVNGGALGGISIPSSVVKPFDNMPFKIATLLLFFAVSVFVFEFTKAGRRMKFVGGNPLCAYLTGIKADKYTILAFVMAGIGIGLGAFLTLVYTPSVTTTTASSIGMNIFIAIVFGGMPISGGARSRIYAALVGGFSYMLLNDILEIVIDSSAAYGITQVISAVFFLIVVYITGMNYKTALLPR
>NC_014387.1|WP_013280305.1|1111148_1112648_+|sugar-ABC-transporter-ATP-binding-protein
MNTPILEMKNITKKFGSVTALNGVDLEVYPGEIRGLIGENGSGKSTISSIAAGMQKATSGQMSYEGNAWEPESMIDALNKGIGMVVQESGTITGITVAENIFLAEMKKFKKGLLVDRKRLFEEADRALSNIGITSISGKDMMDSLSFQDRKLVEIAKVILKKPKILVIDETSTALSHDGRQIMYGIMKKMKKEGGSVLFISHDLEEIMEVCDTLTVLRDGNLIRTFAKEEFDEELIRTSMIGREIEGDYYRPDFSCSFLDEEAIVVKNLCFKDKLKDVSLTLHCGEILGIGGLADCGMHELGEAMFGALKPESGTVISLKGRQIKSPHNAMTDKIGYVSKDRDRKSLCLEASIKDNIAIAGMNIFKSGAGLITRSAERKYVDAQIDALRIKCSGRDQAVAQLSGGNKQKVVFGKWIGCDSKILILDCPTRGVDIGVKQAMYQLMSQLKSEGKAILMISEELPELIGMSDRVLIMKNGEITGEFQRSKDLSESDIIGCMI
>NC_014387.1|WP_013280316.1|1127609_1127912_+|hypothetical-protein
MLIEQNTFFNLMHYEYGEAFFGSYKGMRYRLAREPLENVKFIPVDKRGPATLMATVWPEPYSYGMTDKKLMTSENFEVSQEGFEAAVKWINDQYENGNWQ
>NC_014387.1|WP_042256560.1|1128040_1129048_+|deoxyguanosinetriphosphate-triphosphohydrolase
MKIREQLEEREAQILSKYATLSSESKGREIDEKPCDIRPCFQRDRDRILYSKSFRRLKDKTQVFLSPEGDHYRTRMTHTLEVSQNARTIAKALRLNEDLAEAIALGHDLGHTPFGHAGERALNEVCPFGFKHNEQSLRIVEKLENYGQGLNLTWEVRDGILNHEMDLRPATLEGRVVRLSDKIAYMHHDMDDAIRGGILVESDIPRDLAKVIGNSNREWIDTFIHDIISVSMDTDDIRMSDEVYDAFHRLRKFMFERVYTNPVAKGQEGKVEDMIKILYHYYIDHIDKIPEYLKRMMEEGVPKERLVCDYVSSMTDRYAVAVFEEVYIPRSWGVL
>NC_014387.1|WP_013280318.1|1129050_1130829_+|DNA-primase
MRYSDEIIEEVRSRNDIVDVVGQYVHLQKKGANYFGLCPFHNEKSGSFSVSGHKQMYYCFGCGAGGNVITFLMKYDNLTFTEAVKQLADRAGIKLPDEDDSPAAKAMRDKRQILLDINKEAAKYYYYQLRGRNGQKGMEYFRGRKLTDETMQHFGLGYSNITSDDLVKHLKSLGYEDSQIIDAGLASYDEKYGTHDKFWNRVMFPIQDASQKVIGFGGRVLGDGKPKYLNSPETLIFDKSRNLFGLNYAKNSRAGYMIICEGYMDVIAMHQAGFTMAVASLGTAFTTGQAMILKRYTDEVILSYDSDEAGTKAALRGIGILKEAGLKGKVLDLRPHKDPDEFIKNEGKEAFEERIRNAESTFFFEVRVMESHRNLADPEDKTEFYRDIARKLCEFEEPLERENYTEAVAARYNIAIADLKGLVASYAGRAGMVTPARRPESGIQSKKKPEDGARKNQRLLLTWLTDEPDIYPKVAAWVTPDDFSDDLYRKVATEVFTGMANGNFSPAAILDHFTEEEQYGQVAEMFNTNLVDIETKDQRRKAFRDIILGVKQAGYDRQKKELKPDDPDYLNKTIQGKKALEKLAHANISPDD
>NC_014387.1|WP_026663497.1|1131207_1132422_+|RNA-polymerase-sigma-factor-RpoD
MDEATRELFSQKVKEILALAKKKKNVLEYAEISDFFAELNLNEEQFDNVLEVLENSGIDVLRVSEDDVDDIPDDDDMLLVDDDEEVDMENIDLSVPDGISIEDPVRMYLKEIGKVPLLTADQEIDLAQAMEAGADAEKELADDKDVNKLSDARKKELNAIIYEGEEAKKRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDFRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRVSRQLLQELGREPLPEEVAKEMNMPVERVREILKISQEPVSLETPIGEEEDSHLGDFIQDDNVPVPADAAAFTLLKEQLVEVLGTLTEREQKVLRLRFGLDDGRARTLEEVGKEFNVTRERIRQIEAKALRKLRHPSRSRKLKDYLD
>NC_014387.1|WP_081441803.1|1132491_1133277_+|SAM-dependent-methyltransferase
MLRQTDADAIEEGSNDLNDIDKKPVVADIGCDHGYVSIYLVESGIASRAIAMDVRKGPLSGALNNIHDFGFSDHIKTRLSDGLKALEPGEADAIIIAGMGGKLMMRILEEGDPVALGVRFGVLQPQSDLDEFRKYLRDKGYVILDEKIVFDDGKYYFPMKVSFVGERAAGRLGRKRDHYADAIALLTEKCGCDVERAEHICDRFGECNILHGDPLLQEYCRHGAEVTAAILEELKGKGQTRRYEELRTDLAETTAVLQLFE
>NC_014387.1|WP_013280321.1|1133345_1134998_+|nucleoside-kinase
MSIITINGIQKEYNKGVTYEEIAKEYQNQYNSRIAAVMFNGKIRELMKTVKKDGELSFITFSDTIGYKTMRRTAIMLLIKAVRDVGGDKQLKTRVEFTIGNGYYCTIKGDIKVDDEFAAKVSDRIKFLISEKMPITKRVYPLDDAIEIFKKQGMDDKVALLKYRRSSEINIYKLGDLYDYFYGYMLPNTSYIENFQVECYHGGLLFTLPTKQEPEKVVVSEPREKLFNTMMLSSDWGAMQGIANVGDLNNMICEGRINEMILVQEALQESRIADIARKIFKRIDVKFVMIAGPSSSGKTSFANRLSIQLRTYGLTPHPISLDNYFVDREKTPLNEDGSYNFECLEALDVERFNQDMTRLLKGERVEMPEFNFVTGKREMNGDFLQLGKNDVLVIEGIHGLNEKMSYALPSESKFKIYISALTTLSIDNHNRIPTTDGRLLRRIVRDARTRGASAKKTISMWGSVRAGEEENIFPFQEEADEMFNSAQIYELAVIKQYAEPLLFNIGKDEPEYYEAKRLLKFLDYFVSVDSSFLPRNSICREFVGGSCFKV
>NC_014387.1|WP_013280322.1|1135088_1137650_-|GGDEF-domain-containing-protein
MGINGKTTAEFEQYIIDNLDIALKEEWIKAYHQPLIRAASGKVSDEEAFAKWEDPKYGTFSASEFVPILERKKLTYKLDLYMAERILKKIKSQGEHGLYMVPESINIAKTDFDRCDMVTEIAKRIDASGLSRDKLSVELSERTISSDVDFMKTQIERFHNEGIKVWMDDYGSGYSSLLLLLQIRFDLLKVDKAFVDQIEHSEKGRIILTELVKTALSLGMDTVAEGVETRAQSEFLREIGCTKLQGYFYTPALSLADIIERNEKGIQIGFENPAEVDYFEQLGKVNLYDLSISTNDDYSQDTYFDTMPMVIFSIDDVCAKFIRGNKTFREFIENNYKHLLEIDRFMFENFKPGSGYYSFNAVRQCAADGKRVIIDDRLKDGRSIQLLIRRIAVNPVTHSAAVAICILSVSNYNSEENLTYNYVARILSQDYIRLYFVDMDTENYTAYFSDGPNRDIKIDRRGSNFFNFTNDDFDLNMLPEDKEQLIKSFTKENVAHGIKNNEIFSVVTRVIFDEKPIFVSIKAVKVHGNGNNIIVGISDADAQIKDREALEKAREERLIYSRIGALNGDFVYIYTIDPKTMHFIKYNPSDNNSDMNLPAEGDDFFNTVYKRIPVGIYHEDVAAYQAAFTKENVFRQIKNTGIFEHHHRLNFNGKPVYVVMKATIVHEDDSDLLIIGIINVDERVKKELEYAKSLDAAENKAVIDDLTGIKNKTAYSEAERKINEQIANKEMSPFAIAVFDINDLKQVNDTLGHQAGDTLIQNGCAMICQHFKHSPVFRVGGDEFVAILKGYDYNNVVRLMDNFYKHNLENKAKGEVVVAAGMSKYDNDKAVATIFKRADEQMYANKKKLKKSE
>NC_014387.1|WP_042256562.1|1137883_1139575_+|von-Willebrand-factor-type-A-domain-containing-protein
MKKNAKGLSLLIGSSLLMTTLAGCGGTSNMTDSTASEAEYYQNDTYTEGAAQAPVNSDAKSADERGKYSAGTNNNYKYSDNTTDNYYGDKKVINNNESYTKPEENGFNLVMNQPLSTFAADVDTASYSNVRRMIEDGYAVGEIDPESVRPEEFINYFNYDLYEPEKGDLFGITTEVSACPWNSDNQLMFVGMKTGEIDMEEAPVSNLVFLIDVSGSMSSRNKLPLLQKSFDELVDSLPDEGTISIVTYSGEEKVVLSGEPMSNKKGIKKAIDKLHANGCTNGQAGMQKAYEIAQKYFIEGGNNRVIMATDGDLNVGISDLDDLEKFITDKKDEGVFLSILGFGEGNYKDDKMQTLADCGNGNYSYIDSLEEGKKVLVDEMSSTLYTVAKDVKLQVEFNPANVNAYRLIGYENRMMDDQDFNDDTKDGGEIGAGHSVVALYEIVPARSPKAIDLKYQDEQKAVSGEKVKYAHEFATVSVRYKDPDDDKSQLFSVVVGDDVVTENPSDDFKFAGSVAEFAMILENSENKGTSSFEDIIKTYKELEETDDYQDEFFYLVKTLSKRS
>NC_014387.1|WP_143754332.1|1139766_1140219_+|sigma-70-family-RNA-polymerase-sigma-factor
MDKYGNIILRVAYSYLHNMEDAEDILQDTLIQFLRNNPTFANDSHEKAWLITVASNLSKNKILYLKRRQSDELSEELVADKDKEDLSYVWEAVKALPDKYREVVHLFYQEGYSTKEIAEILSRNESTVRSDLKRGRDKLKKILKEAYDFG
>NC_014387.1|WP_042256566.1|1140211_1141006_+|DUF4367-domain-containing-protein
MGKYNDVMNKIEVTEEMRSRILQNIADEFKDEEFKDEEFKAEKSKGEDAIVRDLESDNDNTIDFKSIIRYAGLAAAAVILFVGGAVVFGSRGNGLMKTTTMSEVAMEVAHEAAADLHHETADDVKQENELIKGSWVKYDSVQKLSKVAGAEFSEIEYLSSISSETDYYLDGETTATIVYDVTGNQITVRETKLADVAKTGGAFAEDQTPQQITIDGVDVRLYGTEDGFDTAIWVINEIEYTLESVEKISLDEMTELMNNIFTFD

Crispr_ID: NC_014387_5

• CRISPR_ID: NC_014387_5
• CRISPR_location: 2264584-2264686
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_014387_5

Consensus_repeat	Method
TCGCGATATACGCATGGCTTCGCTTCGCTCTCGCCATGC	CRISPRCasFinder

spacers of NC_014387_5

>5.1|2264623|25|NC_014387|CRISPRCasFinder
ATATATCTAGTCAAACTACTTTTGC

CRISPR arrays and Neighbor proteins around NC_014387_5

CRISPR arrays

The CRISPR arrays of NC_014387_5

>merge|NC_014387|5|2264584-2264686|CRISPRCasFinder
TCGCGATATACGCATGGCTTCGCTTCGCTCTCGCCATGCATATATCTAGTCAAACTACTTTTGCTCGCGATATACGCATGGCTTTGCTTCGCTCTCGCCATGC

>NC_014387|5|5|2264584-2264686|CRISPRCasFinder
TCGCGATATACGCATGGCTTCGCTTCGCTCTCGCCATGC	ATATATCTAGTCAAACTACTTTTGC
TCGCGATATACGCATGGCTTTGCTTCGCTCTCGCCATGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014387.1|WP_042256852.1|2258102_2258792_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_014387.1|WP_013281232.1|2254354_2255326_-|DUF1963-domain-containing-protein	unknown	unknown	gnl|CDD|370378
NC_014387.1|WP_013281246.1|2272426_2273242_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_014387.1|WP_013281236.1|2258859_2259645_-|DUF975-family-protein	unknown	unknown	gnl|CDD|283754
NC_014387.1|WP_013281237.1|2259948_2260584_-|L,D-transpeptidase	unknown	unknown	gnl|CDD|341130
NC_014387.1|WP_013281239.1|2263203_2264547_-|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240542
NC_014387.1|WP_052301815.1|2252696_2254331_-|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|173412
NC_014387.1|WP_143754281.1|2270706_2271465_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224048
NC_014387.1|WP_013281234.1|2256996_2258082_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_014387.1|WP_013281245.1|2271632_2272436_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
NC_014387.1|WP_026661880.1|2270128_2270557_-|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_013281241.1|2267155_2267890_-|epoxyqueuosine-reductase-QueH	unknown	unknown	gnl|CDD|376894
NC_014387.1|WP_013281242.1|2267983_2269516_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|223247
NC_014387.1|WP_013281247.1|2273248_2274193_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_014387.1|WP_013281240.1|2264815_2266585_-|arginine--tRNA-ligase	unknown	unknown	gnl|CDD|223097
NC_014387.1|WP_042256857.1|2260558_2263072_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|227334
NC_014387.1|WP_052301816.1|2255326_2256364_-|esterase-family-protein	unknown	unknown	gnl|CDD|225256
NC_014387.1|WP_042257830.1|2274299_2275901_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173881
NC_014387.1|WP_042256859.1|2266740_2267163_-|hypothetical-protein	unknown	unknown	unknown
NC_014387.1|WP_013281230.1|2251300_2252245_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014387.1|WP_042256852.1|2258102_2258792_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.03582e-80
NC_014387.1|WP_013281232.1|2254354_2255326_-|DUF1963-domain-containing-protein	gnl|CDD|370378	pfam09234, DUF1963, Domain of unknown function (DUF1963). This domain is found in a set of hypothetical bacterial proteins. Its exact function has not, as yet, been described.	6.06588e-67
NC_014387.1|WP_013281246.1|2272426_2273242_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.95052e-83
NC_014387.1|WP_013281236.1|2258859_2259645_-|DUF975-family-protein	gnl|CDD|283754	pfam06161, DUF975, Protein of unknown function (DUF975). Family of uncharacterized bacterial proteins.	1.15048e-20
NC_014387.1|WP_013281237.1|2259948_2260584_-|L,D-transpeptidase	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	2.16714e-28
NC_014387.1|WP_013281239.1|2263203_2264547_-|MATE-family-efflux-transporter	gnl|CDD|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	8.38027e-93
NC_014387.1|WP_052301815.1|2252696_2254331_-|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	3.0943e-27
NC_014387.1|WP_143754281.1|2270706_2271465_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	1.07668e-97
NC_014387.1|WP_013281234.1|2256996_2258082_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.57245e-33
NC_014387.1|WP_013281245.1|2271632_2272436_-|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	4.71692e-132
NC_014387.1|WP_013281241.1|2267155_2267890_-|epoxyqueuosine-reductase-QueH	gnl|CDD|376894	pfam02677, DUF208, Uncharacterized BCR, COG1636.	2.64817e-97
NC_014387.1|WP_013281242.1|2267983_2269516_-|AAA-family-ATPase	gnl|CDD|223247	COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and metabolism].	6.41648e-84
NC_014387.1|WP_013281247.1|2273248_2274193_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.71625e-103
NC_014387.1|WP_013281240.1|2264815_2266585_-|arginine--tRNA-ligase	gnl|CDD|223097	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	6.99324e-159
NC_014387.1|WP_042256857.1|2260558_2263072_-|EAL-domain-containing-protein	gnl|CDD|227334	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms].	1.01181e-74
NC_014387.1|WP_052301816.1|2255326_2256364_-|esterase-family-protein	gnl|CDD|225256	COG2382, Fes, Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism].	1.33511e-22
NC_014387.1|WP_042257830.1|2274299_2275901_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173881	cd08516, PBP2_NikA_DppA_OppA_like_11, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.24171e-166
NC_014387.1|WP_013281230.1|2251300_2252245_-|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.30557e-22

Protein sequences

>NC_014387.1|WP_013281239.1|2263203_2264547_-|MATE-family-efflux-transporter
MTQDKHMFSNRKLLLLLIPIIAEQFLNSLMGMADSMMVSNVGAAALSGVSLVDSINNLVVQAFNALATGGVIICSTYVGQKDMKRANEAARQVILVSAFISFVVMLSCLIFRGWLLRVIFGQIEPDVYQAASIYFILTILSYPGISLAAAGSAIFRAQSNTRLPMNVAIVSNILNVAGNALLIWGFGLGVYGAAIATLASRIFSAVVLLYLLRRDDQQIFIRQYHKIRPDMDKIKRILGMGIPNGIENSMFQFGKLAIQSSVSTLGTMAIAAQAMTNIFENVNGVAGIGVGIGLMTITGQCLGAGRKDEAIYYTKKMIGWGYIAILVSCLFTYAIARPVTILAHMEAESAALCIYMLGWITIAKPLLWAPSFITPYAMRAAGDVKFSMIIATLTMWLCRVTLATFLIRVVHMGAMGVWIGMFADWAIRGIIFTIRFMRGKWIHKVVE
>NC_014387.1|WP_042256857.1|2260558_2263072_-|EAL-domain-containing-protein
MRYALTAIGILLLIAAIITLVLSIRSDNQSNDVRRPTEVNHRVLFLCAYNSLYFTYDDQVEGLKQALYPHGIEFDVVYMDTKSYGTPNDKLVFYEFFKDRLRKAPEYEAILLGDDDALEFALTYQEELFEGIPMVFFGINDIDFAVEAAQNPMATGFYEKDYLRDCMEIAMKAMPDRKTLVALHDESAAGAADMDIFFSYDQKYPDYVFRDIDTAEFTQAELIGLLRNLPEDSILFYMTCYNDRYGNTYSMLNRTNTVVMNAKVPIIRNYSGGRNQGVLGGVYMDFIAQTRDAGQIVVDILENGTDISEYPLDLETPSKSEFNYELMQKYGVDESVLPANTSYVNKPISPFEYYKKIIPASVLIVSALLMLIISANMTANLQKNANEQLKTFADNLKNTGSKLKYQADHDELSDLLNRRAIVETLGRILQKDEKYAIMMIDIDGFKVINENYGHVMADQIIKHLAKELKNLAEEQKWQVGRYGGDEFIVMVPDVKLDVDSKEVRQILEIFREPIVAGEETLALSASVGVSNSDGASNPEQHIINAEIAMYEAKEHGKNTAFVYADEMQRKIQEENRLKALVTEAFDENLFYMVYQPKIETATGKTIGFEALVRARNIQSGPSTFIPIIEKNGWVIRLGRMVTEQVIRQMALWRDQGKELIPISINFSSKQVNDLGFMNFIKMLMDQYDISHKFIQIEITESLLIEQNIQTQKLFDEFKDMGFRILMDDFGTGYSSLGYLIYIPIDEIKLDKSLVDAYLVPGKDNFIGDVIKLVHDINKTIIIEGVEEKWQYERLREFKADAVQGYYFSKPLEADEAIKFMAQSEERKCRNEKMDFLK
>NC_014387.1|WP_013281237.1|2259948_2260584_-|L,D-transpeptidase
MRKWIFLSKRIAAILVFVGVMCTISLSAKAGDFDPDFYAAQYPDVVAAYGTNPNALYSHYLTFGVNEHRYKNREDMIAAQNGQQISQDVPSTYVDVDIDNQTMNYYVDGVSVLSSAVVTGNTQNGNGTPRGVFFIDSKIPGKYLVGPTWNVWVNRWMRFTGAVGLHDASWRSEFGGDIYTYNGSHGCVNLPSDVANTLYDMVSVGTMVVVH
>NC_014387.1|WP_013281236.1|2258859_2259645_-|DUF975-family-protein
MWTRKELKEKGKKAFLFNYWKTVLVSLVLVILVIGTSGSVAGRGRSNPANDRGEKSAVTTMTETAEDTINEHSLGNKQVELPPAAKAVLAVLAVIVGIVGVGSALAFMAFLVNPFEVGCRRFFLRNLNQKAKFSEVAFAFDNNYLNIVKICFFMTIYTFLWGLLLIIPGIIKSYEYRMIPYILADHPDMSQKEVFAKSKELMKGQKWRAFVLDLSFIGWEILSLLTARVLGVLYVTPYRDMTNAALYERLEYGNLAAEENN
>NC_014387.1|WP_042256852.1|2258102_2258792_-|response-regulator-transcription-factor
MDKILIADDETEIRSLLKLYLENEGYAVAEAGDGQEALKILAGGDISLCLLDVMMPEMDGFHVLKEMRKNNNIPVIIISARDTDPDKILGLDLGADDYMIKPFNPLEAVARVRSNLRRFHALKGDLQPQTGKIIELLDLKLDTEACILYRQGEKIELTSNELKMMELFMENPGKVFTKEKIYEYVWGDTYVVADNNIMVAISKLRSKLCDDPSAYIRTVRGLGYRMEKE
>NC_014387.1|WP_013281234.1|2256996_2258082_-|HAMP-domain-containing-histidine-kinase
MDKFKYFLIKHLVFVMVIVVAIELILTIIFNSLIFPFIGFLLGQPEISSLSLSSIPFFIWGLISGNSAFVFNALETSTVILLILFSLLLVVLPIIVGILIYARIVTRQMEIFEKERIEERKSYEARRNLMLSDFAHDLRTPIMTISGYANAITDGMVKDEAQRNEYLSAIAAKSKRMAELITILFEYVRVGSEGFTLTRKRVDLHALLTEVIAGFYPDLEKAGIDVNIDIPEDPFYISADELHLKRVIENLIINIIRHNEPGIKAGFIIKKTSGVEFLAVADTGEKIQKSEEELFEPFVKDDDSRSKNEGSGLGLSVARQVMDMHGYEIHLKQPYGDYTKAFVLKFIEADLVDEVLLDGTC
>NC_014387.1|WP_052301816.1|2255326_2256364_-|esterase-family-protein
MKTSSNEAIVEENSGTADASSNEAVADSETSNLSNKETTADSEDLSSFATGIKTEDEAEAADTTFVLNDEIENRCPVIYEATRGNVSYGEFTHGTYYSKTCGMERGYSILLPADYSEDKKYPVLYLLHGIFGDEYSFSQDKSNKIREIVGNMAADGNIDETIVVCPNMYATSDPDQKPGFDSKSVLPYDNFINDLVNDLMPHIESEYSVLTGRENTYLAGFSMGGRETIFITLQRPELFGYVCAISAAPGIVPTKDKFMSHEGQLQESEMKFADDAVVPNVFIVCCGTRDSVVGTYPKQYHEILDVNGADHIWYEITGADHDNNAIKSGLFNLFKQIAYDKKGER
>NC_014387.1|WP_013281232.1|2254354_2255326_-|DUF1963-domain-containing-protein
MGIFSILRALTATNARDAEKAKKTEFDLKNDTGNNTDATGAVFVKENMLVIPREKLDILIERIKKDTERKVINIETEEKADIGLTDSKFGGYPYWPSNMEYPVNSEGDKLILLAQINLSDVSDNRLPETGILQFFISCDDINGLDDEKGYKVVYHKDIDPSVTEASVKELGIRAASDLDHENDEYMPLSKSYSLTFSEDTDFIGSSCNTFESVVAGELKSLYNIDMNEVEIDGYYKLYGFLNADDSDYLSEAFSNAGHKMFGYPFFTQEDPRDNGENDILLFQMDSDYKDIMWGDSGVGGFFISEENLKNLDFDKVVYNWDCY
>NC_014387.1|WP_052301815.1|2252696_2254331_-|SGNH/GDSL-hydrolase-family-protein
MSKDNFRKRNNGTKRSCFKEIMQGLGGKNITIISSVVIAALFVIILLVMFIKSPVFIAWRENGSETQVASEEMAAGEETMNVASGEEDMPVVETATEGMKAESTPDTTVLAKKENAKDGYLNRCVFLGDSRTVAMVNYGFFNDDAALAQIGISHPAFASNKFINNAGKEYTLKSYLSSHQAPVIYILLGVNGINDSSESHYQNTFISLIDSVAKMAPNSNIVLVAIGPVDDNGIYKNSVQNAWIDKYNAFLLETARQKHIFYLDIAEILKGSNGQVKPEYNGGDGLHYSGKGCEAIFRYIVEHPVPGISDEGKYVVKYIKPDPNRMKVTMDDGSGIDEGKIQDLMDMMMGTPENQTASDASTESSSETEEELEKKKAEEEKKKAEEEKKKAEEEKKKAEEEKKKAEEEKKKKAEEEKKAEEEKKKAEEEKKKAEEEEKKKAEEEKKKAEEEQKKAEEEKKKAEEEEQKKAEEEKKKAEEEEQKKAEEEKKKAEEEEKKKVEEENKEESEKKEGEKEENGNSGNSAGEALEGSAGHSEEETVNNP
>NC_014387.1|WP_013281230.1|2251300_2252245_-|phosphatase-PAP2-family-protein
MGVVVGNSFWFDFEVELMEFLQRTIGDTGISIISFFSYFGEELILILLLGFLFWCYDKKAAIYIGTNVMVGLVFTPLIKNFFWRRRPYFDHETIKCLRPVDKKADIYDIAAQGFSFPSGHSTNSATVYGSLARFYKKPVFTAVAFILPLLVGLSRVIVGCHYPTDVLFGWLSGALIIFVIPALVRRFSEEKRWIIYLIIFLISCIGLLYCKTSDYYTGLGLMGGFFLSVEFDRRVVKFENTRKPLWCITRLLGGFIIYFALNTLLKMPFSKVFLDSGVFLANIVRFIRYTIVAFVTIGVYPLVFRVEKVFSKNN
>NC_014387.1|WP_013281240.1|2264815_2266585_-|arginine--tRNA-ligase
MEKVLELISKEVGDAFEAAGYDRELGRVTISNRPDLCEYQCNGAMAGAKKYGKAPFIIADDVAARLQDNSMFDKVESVKPGFLNITVSGDFARGYIVKMLHEKHFGVDRPAHEPTYIIDYGGPNVAKSLHVGHLRSAVIGESIKRILKYTGNKVIGDAHLGDWGLQMGLVITELEVRKPDLCYFDPNYEGPYPKEAPFTVEELGEIYPAASAKSKEDEAFKAKAMDATKKLQDGYKPYRALWHHIMNVSLADLKKNYKNLNVNFDLWKGESDADPVIPGMVEYMKSHGYAHESQGALVVDVAEETDTKEVPPCMILKSDGASLYNTTDLATIKQRMDDNHPEGIIYVVDKRQELYFTQVFRCARKTKLVMPETELHFVGFGTMNGKDGKPFKTRAGGVMPLGDLIAEIDDKMYNRIKEGNPEMPEDEAKDTSHKIALSALKYGDLSNQPSKDYIFDIEKFTSFEGDTGPYILYTMVRIKSILKKYEAEGGNVKEALLANPDSPAMKELMLQLTRFADAIEGAAKDFAPNRICAYIYDLSNAFNSFYHGTKILAEADPDKKSSYIALLATTLKVLETGIDLLGFDAPERM
>NC_014387.1|WP_042256859.1|2266740_2267163_-|hypothetical-protein
MYNQPPKYVMVTPNLRSNDNSNSTVRALNIAAIACMCLARFVPAMGSFLLLFDEYSSGSGFNLYGLNVVLILASLILLIIARVKFPGDSVSKGLLIGFVVRTVFAIMLTIMILVLGIWFVSLYALSDIADIIWELIELFE
>NC_014387.1|WP_013281241.1|2267155_2267890_-|epoxyqueuosine-reductase-QueH
MNKRNYSRELENRIAGFERENRFPRLLLHACCAPCSSYCLEYLREYFDVTVFFYNPNITEEREYRKRVEEEKRLISEYNRQVEENSFEGMNSDSRARRIEIMEGDYVPSDFMHAVKGLEDCPEGGDRCRKCFELRLDETARIARDNGFEFFTTTLTISPLKNADVLNEVGEEAARKINSQARAADPGKEISQIQFLPSDFKKKNGYKRSIELSHKFGLYRQDYCGCGFSKAQREKEKEEKNVNV
>NC_014387.1|WP_013281242.1|2267983_2269516_-|AAA-family-ATPase
MANFTDGNTNVCGLIGNPVRHTLSPLIHNSLAEITGINMVYVPFEVAEGDVSDAVKGALALGVRGLNVTIPYKSDVIPCLEDIDPLAKAIGAVNTLVRTPNGGFKGYNTDMTGLYHSMQDEGVELEGRTVVILGAGGVARPAAFLCASKGAKKVYILNRTYERAMDVAGEVNRALFDLSREDLVTADGINAEGDPLDIPEIVVPMKIENYRDLYEEKEKFITLQCTSVGLFPDVNSAIIEDSEFYEHISVGIDMVYRPLETKFMKLTAEAGAKAVSGLKMLLYQAIDAYELWFESELFAEMQKSGEDKKTDAEQKAVKISKEQADEIYKSLVMEVTGARNIILEGFMGSGKTTVSEILADKLDLELLDTDAAIVEAEGRSISDIFETDGEESFRDMETALLETASSEHFREMVISLGGGLVLRKENRELLQELGKVVYLRTKPETVYERVRYDDSRPLLKTADPLSTIRKMQSDRGSIYELAADFIIDTDDLTPSEIADRIIEELGIVIV
>NC_014387.1|WP_026661880.1|2270128_2270557_-|hypothetical-protein
MALDRINGFVNYNAYNIPPAVDNNIKVGTQAPQNAPLKAPEKPVEAQKEEPKKGLDLTVEELPARENASIENVAISFGMYDSSSIDLFGEKGLASEDMKQAISGMQRDKILHEYQYFVGGKDLTGKQSNIITGTEDGLVIKL
>NC_014387.1|WP_143754281.1|2270706_2271465_-|ATP-binding-cassette-domain-containing-protein
MEKEKVLRVTGLNVFYKNRKRKLFSRKNKKIQALFDVSFDMDEGEVLAIAGESGCGKSTLARAIVGINKDYQGEIWQKYGRPMMVFQDPYNSLNPAKRIGWLLEEPLKVDKERKWTSEERRKRVEEIMQEIELPLSMLDRYPSQLSGGQRQRVCIGIALMREPKLLIADEPVSALDVTIQAQIMELLNNLHRKHGISIIFISHDLRVVYQISDHVMVMKNGHVVEYGATRDVYRNPQADYTIQLLKAAGITK
>NC_014387.1|WP_013281245.1|2271632_2272436_-|ABC-transporter-ATP-binding-protein
MGIILDVTDLHIEFHDSDSPETAVEDFDLMLADGEIVGIVGESGSGKSMSALAIAGLLSRHAIKKTGRIMFEGHDLLTCDRKTLRSFQGDEISIIFQEPMTSLNPVKRIGWQVEEPLRIHHPEIKKAERKKRAIDMLKDVGLENAEEVYYMYPHELSGGMRQRVMIAAAMIGNPQILIADEPTTALDVTVQAQIVELLKKINREKRTSIIFISHDLSLVSQLCERVIVMQKGNIVESGDTRTVFTRPIHSYTKKLIAAIPKIDLDNQ
>NC_014387.1|WP_013281246.1|2272426_2273242_-|ABC-transporter-permease
MKNSKLRKLSKNPYVLIGGIIMGLVLAMIILGIFWMPYEPTKMSASEKLQGISLRHIMGTDNMGRDVFSRVMYGSRVTLMIAIGTIIIGAGVGTIIGAITGYYGGMIDEVTMRVIDALFAFPSILLALVIVSVFGVGWTQLVISLGIAFVPSFARIVRGEVLRCKNMDYIENARLQGVSDLRMIFLHILPNIKGVLASSILIGFNNAVLAEAGLSYLGVGSQPPYASLGRMLSDAQQYMFTRPSYVLCPGIVIVLMVLGFAFLGEGIKRWE
>NC_014387.1|WP_013281247.1|2273248_2274193_-|ABC-transporter-permease
MKYTLKKLSSTIVTLIVVSLCVFLAFNVLPGDPAIRMLGLEASPELVAQTREKMGLNDPVLVRYFRWFIAFLQGDFGTSYTYSVPVSSLIMSKVPITLTLGILAFLFTVVISIPVGIATAKYENGILDRIITVINQVIMAIPPFFSGILITFIFGMILKLFTPGGFVSYTEDIRGFLRYLFFPSIAIAFPKIAMTVRMLRGNLIDESGKDYARTAYSRGNNTNGVLYRHVLKNAMIPVITFLGMALADMVAGSIVVEQVFNIPGISRILLSSISNRDYPVVEAIIMGIAIIVIGVNFLVDIIYRVIDPRIEIED
>NC_014387.1|WP_042257830.1|2274299_2275901_-|ABC-transporter-substrate-binding-protein
MNKKIGRMGSSLLMVVLTTLTVALSGCSSDKAGDSAKVDASVEAGTETVTGTETTESTDVADDLSKLTVGIPQDIDGLDPHNSTGAGTREVFYNIFEGLVKADSEGNLNPAVASEYTISDDSKVYTFTLRDGIKFHDGSLVTVEDIKYSLERNMGVDGSEPLIKAYGKIDSVNIVDDSHVEVVLKEADSDFLTQLTVAIIPASNEHPETTPIGTGPYKYVSNSPQENFVVTRFDDYWGEKAYIKDVVFKIEANMDAIVLDLEGGSIDMMARVTPTQVSQLSDKFEVYEGTMNLVQALYLNNAVKPFDDVRVRQALCYAVNPQEIMDFVSEGAGTEVGSAMFPAFSKYYMPELNDTYNTDADKAKELLAEAGYPDGFEFTITVPSNYGQHVDTAQVISEELKEIGVTAKIQEIEWNSWVSDVYSGREFEATVVGIDASTLSASALLSRYVSDNGKNFVNFNSADYDAAYAKASAATDDAEKTTYYKECETILSKEAASVYIQDLPEFVVLNKKFTGYTFYPLYVQDIAKIRPAQ

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014387_3	3.1|785491|25|NC_014387|CRISPRCasFinder	785491-785515	25	NZ_CP033038	Agrobacterium fabrum strain 12D13 plasmid pAt12D13c, complete sequence	27838-27862	2	0.92
NC_014387_3	3.1|785491|25|NC_014387|CRISPRCasFinder	785491-785515	25	NC_015724	Cupriavidus necator N-1 plasmid pBB2, complete sequence	416678-416702	3	0.88

1. spacer 3.1|785491|25|NC_014387|CRISPRCasFinder matches to NZ_CP033038 (Agrobacterium fabrum strain 12D13 plasmid pAt12D13c, complete sequence) position: , mismatch: 2, identity: 0.92

tgcggcttgcggaagcgcttgcggg	CRISPR spacer
tgcggcttgcggaagcgcttgcgtc	Protospacer
***********************  

2. spacer 3.1|785491|25|NC_014387|CRISPRCasFinder matches to NC_015724 (Cupriavidus necator N-1 plasmid pBB2, complete sequence) position: , mismatch: 3, identity: 0.88

tgcggcttgcggaagcgcttgcggg	CRISPR spacer
ttcagctcgcggaagcgcttgcggg	Protospacer
* *.***.*****************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1385734 : 1458193	54	Tupanvirus(22.22%)	transposase,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_014387|1385734:1458193|DBSCAN-SWA
ATCATGCTATATTATCGGTTATCATGCCCCACATGAAGCAGGCAAGTTCTCTTGCTATTGCAGTTTTAGCCACATTGTGTTTCTTGCTTTTACCAAGAACCATTTTGTAAAACTTGCGTCTTAGCCTTTCATTAGCTTTATCAGCATATGCAATGACTTGAGGTGAGTTGCCAATCTGACGGGATTTAAGTGCTTTTGATTTATGTCCGATTTGTCCTTTGCTGTATGACTGGGATGATTCTATAAGAAGCTGTCTAACATGACGATTTCCGGCTTTTGTGATTCCAAGCCTTGACTTTTCATCACCACTGGATTCTTCACCAGGCACAAGTCCAAGATATGCAGCAAACTGATTGGCTGATGCAAAACGTTTGAAATCACCTACTTCAACCAATACAGATAGTGCTGTGTGAGTTTGAACCCCGATGAAACAGCAGAGTTTTTTAACAGGCTCTCTGTATTCATCTTTTAAAGCAAGTTCTTCTATTCGCTTGTCTAAACGTTCAAGCTTATCTCTCAAGTTTATGTAGGTCAGCAGATATTCATCGAGTATTTCTTTATACAGTGCCTCAGGCTTTAATGATTTTAACCAGTTCACATGAGCTTCTGTCCAGTGACTTTTTCCTTCATAGCGATAGTCGTGGCGAAGACAAAACGAAAGTATTTGTTGCTTCACTTTCTTGAGTGCAAGCTTATGATCATCTCTCATACGGAGAAACTCTTTTGTTTCTTCATCTGTAGAAGTAGGAACATGAACAGGACTGTAATTGTGCTGAGCCAGACATTTGCCAATCAATTCAGCATCACGTTTATCAGTTTTAATTCTTTTGCCACTACGCGGTTCAAGCATAGTGGTTGGTGCAAGTATCACACAGTTAACGTTATGATTAGTTAACTGATGATATAAAGTATAGCCGAGACATCCGGCTTCATAACCGCATATAAAGTTTGTATCATTTCCGTAGATGGTTCTAAGGAATTCCAGATATTTTAGGACTTCCTTGTAATCAGCGTGGGTGCGCCTTGTATGAGACGCCTTCTCTGTTTCGATTAAATAATCGCAGAGAGTAAAACTTTCCTTATGTACATCCATTCCTACGTAAACTGTGATATTATTCATTTAGTGACCTCCCTTTGTATGCGGTAATCCCTGTTACCATTGACTCAACATCTTTAGTATACAGGTAAATCCACGTTGCTACATAGTGGAGGTCATTACATATTGTCTAGTATATGTTTCGGTTTTTTTGATAACTGTTAGCGTTAATTATATGAGTGGTAATCTTGTAGAGGAATATTGTCTGCCATTTGTTGTATGGTCAACAATCAGAATTTACAAGTTCATGGAAAACTATGATTTCACAGGAAATGCTTTACTTGAGCCCGAGGATACTGTACTTTATGGAATCACTTGTGGAATATGTTTATTGACAAGAGCAACTAATGCTATGCCTCTTGTGGGAGGGGCTATAGTAATAATTTTGGTGAGCATCCGTAGTAAAGCATTTACAAATTTGTTAAAAAATATAATGTTTTTTGTGATTGCAATGGGGATTGTAGTGGCACCATTTTGTATTTATTTCTTGATCAAAGGCAGCACTGCAGAAATGTTTTTTGCGATGATTACATATAATAAAGAGTATGCGGCTCTTCGAAGACCATGGATTATTGAATCAAATGCGAGAGATATCGTACGTTTTTTTCATTTGTATTTTTCAGTATTTTCTATTTTGCTTGTTGCAGTAGTCAACTGGTTTAACAGGCAATATGCAAAGTTTGCATTCTCATTTATCACGTTTGGAATAGAACTGTTTTTTTATATGTCAAATGACTTATTTGTCCAATACCCTATGGTATGTGCTACTCAGGTCATTTTATTATGCTATGAGATAGAAAAACTGTATCGGAATAAAATTCTGATAGGGGCTAAAATAAATGTTCCTATATTTATAGCGATATGTACGCTCTTGTTTTCTGTAGGTTCATTTTGCAAAACAGCTATTTTGGATGACTTTATTGCACATATATTTGTATATGGAAACTATTCCTACTATTGCACCGAACCTTGGGAAGAGCTTGTTGATATGATTCCTGATAAAAAAGAGCCTTTTGTTACTTATGGTAGTAACGATCTGAAACCGGTTTATGTATTAAAAGATATAGATCCATGCTATAAATATTTTTCTATACAGCCTTGGCACAGTATGTATGATGCCAGTATTGCTGAAGAAATAAGAGCGCAAATGTTATCTAATAAGGCTAAATGGATTTTGTGTGATGAGGTAGGTAGAGATACTATTCTTAGCTTGAATACAAATTATTATATTTATGCGGAAAATGGTGGCTTTTCCTTGCTTGAGTGTAAGTGATGCGGATTTCTTAGCTAAAGGAATTAGTCCTTGCTTTAATAATTCAACATCAGTATCTGTTACCGTGGATAGAATATTAGAGCATTATGGTTTAATGCCATTATCTTCAAGAAGTTTACGGAGACGAGCATTCTCATCTTCAAGGGTAGTATTCTTTGAGGTAAGAGAAGCATTCTCATCAGCAAGAGTAGATACTTCATCAGTAAGAGCTTTTATTGTTTCTTATCGTTTGGCCTGATAACGGAGAAAATCTTCACGATCTCTGGCAACTTTACGGATGTTCTCATCTGTGTGGTAAAGCAGAAATAGAAGCAGCTATTGAATACAAGAATTATAACTAAGCATTTGTCTACACATTGGTGCTTGCCACCGCACATTGTTGTTCAAAGAAACGGACACTGCCTGTCACCACGCACATTGATTGAAAAAAGCAGGCATGGAAGAACTGTTTGGTTTTCTTTTTGATAATGTGGACAAGATGATTGAAGCTAAAGAAGTAAAGATTCTCTTATAAAAAGTTCATATCTTTTAGAAGTGAACAACACCGTATTACTGGTAGCATATGGACGATATAATAATTATTGAATATAGAACAAGCGTTCTATATAATGTTCTCTGGGTGCTACCATTTTCGGTGGGCGGTTGGCTCTTTGCCAGATTTGATCTGAGGGCTCTCAGTAATTAGGAGGGATTGCTTATGAGAAGATTTTGGAAAGGGCAACATTGATGATAGAGACAGCGATAACACTTGTGAGCATTGTTGTTACAATTATAAGTACCATTGTAACAATCATCAGTATTTGCAAGGGTTCAGGAACTGATAACTAAGCATCAAAAAAGACCGCTGTCACTCTAGCAAAGTCGACGGTCTTCTTTGATCTGAAACTATAAACTAGAGCCAACCGTCTATCGGTGGCACCCTTTTATGCTTATATAATAGCACATTCTATTTCTGAATAAAACTGTATATTTGCGCTTCGTATTGAAATGTCTTACTGTGTTCACAGATAAGATTATTAGATATGAGGACGCAGAAAGAATTAAGGAGGCACTGATGATGACGAAAGTTGAACAGCTCTTCTACGAAGAAGCAGCAATAAAGATTGCGAAGAACTTATTGAGAAGTGGAATTGATGTAAATGTGATTGCGCATGATACAAATCTTCCATTGGACAAGGTTCTTGAGCTAAGAGATGATATAACTACTGAAAAAGAATGATAGATAATTAAATAATGAAATTAATGATCCCAGTGCAAAGCATGGATGAGATATGAAATTGTGCGCACTGGGATTTTTGTGTTTACCTGCCTTGTAATCCAAAGAATGTTGTTATTCTTTATTCTTATTTGAAGTACTTGATAGCATTTTCTTTACATAGAGGTAGACTCTGTCTTTTTGCTCTTCAGAAAGATCACTATATTTTTCAACTATGAATCGTAGCCGTTTATCTCTGTCTTTGATTATATAATCCAAAGGATTCTTGTCATCTATTTTATTAGTGAGATATTCTACAGAAGTGCCTAGAACAAGGGATAATACCCTGATTACAGAAGCAGAGGGAGAACGCTCGCCACTTTCATATCTGGTATATGCGCTTTGAAGTATACCAGCTTCTTCAGCTAAACGATTTTTGCTCCAGCCTTTTGCCTCGCGCATTTCTTTTAATCTTTTTGTATCTAGAACTGGTTTCATGTTCCCTGTTAGCCTTCCAATTTATTTAATGAAATTATTATACATGGTTGACAATTAAAAATAAACATTTTAATATTTATCATATGTCATAGACATATATTATAGACGAAATATTTAGGCATATGGAGGTATGATGAAGTTTTTTAAGAGGAAGATTAATTATGGGCAGAATAATAAAAGTAACAAAACAGATTTGATAGAAGCAGCTCGAAGTCTGATGCAGGATTACTGGAATACATCTGCTAATAAAATCCATTTTTTGGTTTCAAGGGTCACTTGTAGGCATATTTATCTTATTTGTATGTACGAAGGAAATGATTTGGACATAAATAATTTGAAGACAGCTGAGATGATTTATATGGTGAAACTTCTTAATTTGGCAGGACTTGAGAATAAAGAGCCTAATGAAGAACAGGAATTTTTAGAGAGTTCTTTTTATGACTTTATGGAAAACTTAAGGCTTGCCAGGAATATATATTCAGATTTAGAGCTGGCTTATAATCCTTTAAAGATAGATTTACAGCAGGAAGTTATTCCTGAAAAGCTTTTTGATACGAACATAGAACCTGTAGAGAAGGCGTATAGCTTTATTCCAAGTGATGAACTGACTAGAATCAGATGTTCAGAGAATACAGAAAGGGATGATGTAGACAGGCCAGTTCACTATTTAGTTTATAGCAATAACAGGAAGGTGATTGATGAAATAAATGAAGATCTTATATATAGGCTGCGAAAATATAAGAGGATAACATCCAGGCGGTATCTCGAAATATCACGAAATAATATAAAGCCACGGGATAAGAATAATTATAGGATAGGAAATCTTAATAACCTTGATGGAGGACTTGTAATAGTTAATCTTGATGATACGGTCAATGATGACTTTGAAGTGCTTGTTAATTCTGTTTATTCAGAACCCGGAAAATACAAAGGGAAATACACGGTAATTTTTAACTTGTGTGAAGCAGATGACGCTAGAGTTAGCGTGATAAAGAGAATTTGCGATTTTTGGTCATTTGTTGTGATATCTGATGGCAAGTTAGAAAGAGCTAAAGCAATAAAACTTCTTGATCAAATAGCTGAGGAAAACGACGTCGTACTCATAGATAGTTATTATGATGAAATTCTGGAACCCGGTAAAAAATATTTAAGGGATGAGCTTATTGCAGCTTTTAGAAAGTGGTACTTGAATAGATATAATATCAGGAAAAATTACCCAGCATATACAACTTATATTATAAACCTAAGTAATGTTGATGAACTGAGTTGCCCTTCATACCATGAGCTTGAGTCGTTGATTGGACTTAAAAATGTAAAGACTCTATGCAAGGATATTATTAGTTTTTATCAAATGGAGAAGTTGAGGAAAGAGAAATACTCGTCACTTAAAGATATTGGAATGCATATGGTATTTCAGGGAAATCCAGGGACAGCCAAAACTACAGTTGCCAGAATAATGGCCAGGATATTTAAAGAAAAGGGAATACTATCAAAAGGTGACTTGATTGAAGTTGGACGTGCGAATCTTGTAGAAAAATATGTAGGACAAACCGCACCAAATGTAAAGAGTTACTTTGAAAAGGCAAAGGGAAGTGTGCTTTTTATTGATGAAGCATATTCTCTTGCAGATGGGGAAGGAAAAGGAAGTTATGGAACTGAAGCAATTAATACTATAGTCCAAGAGATGGAAAACAACAGAGATGACGTTGTGGTTATTTTTGCCGGCTACAAGAAAGAAATGAAAGAATTCTTAAAAGTAAATAGTGGTCTGTCCAGTAGAATCTCATTTTTTGTAGATTTCCCGGATTATTCTGACGATGAGTTATTTGAGATTTTGACGAAAATGGCAAAAGATAACCATTACACTTTAGCAGATGATGTTCGCTCAGCTTTTGAAAATTATATCAATAGTACTGTTACAAGTATCGGTAATGGAAGATTTGTAAGAAATGCTTTTGAAAGAGCTAGAATCAGGCAATCTAGCAGGATATGTAAGTTGCCTGTAAAACAGCTGACAAAGGAGCTATTTGTTCTTTCAGGGCAGGACTTTGGAGGATTGCATGACTAAAGAAAAATTTTGTGAACAATTGTCTGAAAGGCTGAATGCTAAATATGGGTCATTAGGGTATAAAACTGATATGTAATGACCTCCTGTCAAGCAAAAAATGACTGGAATCACCACAAACATATTTAATTGTTGCTGAAGGCACCTTGAAAGAGCCTCGGGGTATCAGTTCCCGGCATTGGCCACTCTGATATACGTGGATTGGTTACCGACAGGTCAATGGTCCGCCGTGAGCTCTACCGTCTAGTTGCGTGGATCACAAATTTCTCTGTGCCAACATAGTTTTATCGTAGATAGCTCTAACCTTGAAATGGCCGAAGCCCTTTCAAGATGTCTTCAGTTGGTACTTGTTGGTGGCCAGATGTAAATGGCGTAAGCCATCTTACATCTGCTTGATTACCCGCTATAACAGCGGGGTGAAGATGTCAAGGCTGCGAAGCACCGCCCACGGCGGCTTGGCCTTGATATCGGAGGCGCGATGTTATACCTGATCATGCTATATTATCGGTTATCATGCCCCACATGAAGCAGGCAAGTTCTCTTGCTATTGCAGTTTTAGCCACATTGTGTTTCTTGCTTTTACCAAGAACCATTTTGTAAAACTTGCGTCTTAGCCTTTCATTAGCTTTATCAGCATATGCAATGACTTGAGGTGAGTTGCCAATCTGACGGGATTTAAGTGCTTTTGATTTATGTCCGATTTGTCCTTTGCTGTATGACTGGGATGATTCTATAAGAAGCTGTCTAACATGACGATTTCCGGCTTTTGTGATTCCAAGCCTTGACTTTTCATCACCACTGGATTCTTCACCAGGCACAAGTCCAAGATATGCAGCAAACTGATTGGCTGATGCAAAACGTTTGAAATCACCTACTTCAACCAATACAGATAGTGCTGTGTGAGTTTGAACCCCGATGAAACAGCAGAGTTTTTTAACAGGCTCTCTGTATTCATCTTTTAAAGCAAGTTCTTCTATTCGCTTGTCTAAACGTTCAAGCTTATCTCTCAAGTTTATGTAGGTCAGCAGATATTCATCGAGTATTTCTTTATACAGTGCCTCAGGCTTTAATGATTTTAACCAGTTCACATGAGCTTCTGTCCAGTGACTTTTTCCTTCATAGCGATAGTCGTGGCGAAGACAAAACGAAAGTATTTGTTGCTTCACTTTCTTGAGTGCAAGCTTATGATCATCTCTCATACGGAGAAACTCTTTTGTTTCTTCATCTGTAGAAGTAGGAACATGAACAGGACTGTAATTGTGCTGAGCCAGACATTTGCCAATCAATTCAGCATCACGTTTATCAGTTTTAATTCTTTTGCCACTACGCGGTTCAAGCATAGTGGTTGGTGCAAGTATCACACAGTTAACGTTATGATTAGTTAACTGATGATATAAAGTATAGCCGAGACATCCGGCTTCATAACCGCATATAAAGTTTGTATCATTTCCGTAGATGGTTCTAAGGAATTCCAGATATTTTAGGACTTCCTTGTAATCAGCGTGGGTGCGCCTTGTATGAGACGCCTTCTCTGTTTCGATTAAATAATCGCAGAGAGTAAAACTTTCCTTATGTACATCCATTCCTACGTAAACTGTGATATTATTCATTTAGTGACCTCCCTTTGTATGCGGTAATCCCTGTTACCATTGACTCAACATCTTTAGTATACAGGTAAATCCACGTTGCTACATAGTGGAGGTCATTACATATTGTCTAGAATTATAAAAGAAGGATATACATCTGAGGACCGAAAAGAGTTGGAATTTATTAAAGAAACAAATTTAAAATACTTTAAAAATCAAGAGGAGTTATTAGGTGGGGACATAATACTCCTTGAAAAACAAGGTGATTCATCTGTGAGGCAGGAGATAGATTATCTGATCGAATCCTTTAATGATGGGGGATGGGAATATGTGGAATCGATCTTTGATAAAAATATAGAGCTATGCGGGTATTCAGATGTAATTAGGGACGAAATTTCTGATTTTGATATCATGAAAGATAATATAATAGTAAGAGTATTAAATTATGAGCTGCACAAAAATGAATTGGAGGACAGAGTATACAGAAAAATAGGTGATTTTGTGCTTTCTGTGAATGGCCTGATATTTTCAAACAGCAAAATAACAAGCTTCTTTAAAATCTCAGCAGATTTTTTAAAGGCTTGGGGTATTACCGAAGACGAAGTGATTGAAATTGGGTTAGAAAATACAAGAAGATTATTTCCGCCAAGGGTTTACGGCGTTGAATATGCTCTAAAGATAAAGACTATAACACAAGGTGATGGAGACTATATGAATAATAGTCAAAATATCAGGCTTGGAAACTTAGGCGAAGACACATTTGTTGCCTATGGAACTCAGAATGGTGCAACTAGTTTCTTTTACCCTGGAGTAAAAGAGAAGATTGCCGAAATGCTAGGCGGAGAGGATTATTATGTAGTATTTACTTCAACTGAAGATTTTCATGTACATAAATGCTCACAAAATGATGCTGCGAGCTTAGAAAAACGTCTTATTGATATGAATAAATACTTTCCATTGGGTGAAATGCTGACTGAGAAAATATATAAGTATAGCGTAGATACTGGAGAGCTTACTGAAGTGTAGGCCATTTTGTCTACAGTCTGGAACAACCACTGACTATTGATAGATAGCCAGTGGTTGTTATTTTTGTCTCATTCTATTTTAGAGAAATATATCCTGTAGAGAAGTCATATCTTGGGTCTTCCTCGCAGGAGAAGAAGATAGAAAGTGAACAGTCTTTTTTGCTGATATCTTCTTCAGCATCGTAAGAATGTATGTTAGATATAAAGGTGTAGCCAGCCGGAACTTGTGATTCGGAGAAACAGTATAGTCCGTGTTCGTCTCCTGCTATCTTAACTTCTGTACCCTTGATCATGTAGTCTTTATCTGTCTTGTTTACAACGTAGAGTAAATAACGAGGGTTATAGTCTTCTTCTGTATAAATAGAGTATACATCTGCCTTATCACTTGTGAAGATGAGATTAGCGTCTTGCTTTACTGGAAGAGTGTAGCTAAAGTCTGTATCGGTGCGTATGCAGATGGGAGTTTCAGCAGCCTCATTGTAAGTGAAGTCATCATTACTGATCGATACTCTGGAAAAAATAATTTCAGAAACAGACTGATATGGCATTTCATATATTTTCTCATATATCACAGAATCGCTATTTCTCTTGAAGTAATCATAGGTTGATATGTAATATGAGGACTGAGAGTTTCCGTTTATTGAGTTTGAATTGATAGTGACAAGTATATCGCTGTTTAGTCTGTTTATTACGTGAATTGCGGCCTTGACATTGCCATATTTGTATCCGTCAATTTCGTTATCCCTTACTCTGTCAGAAACATAGAATTTTTCAAGAGTGATTGTTACGCGACCATCATCGAACAACACTCCGTCACCTACGATATTATAAGAGGCTTCTGTATAGTTTTCATATTTGGTATCGTTTAATTCAGTTTTACCCATATAACGGCTGTTTCTGGCGTTATTTAAGTAGATTATAGCAACAGTTATAGCTGCAAGATTGAGGATAGCTATTATAAAAATACTTCTCTTTATTCTTGCAAGTATTTTACCGCTTTCTTCGGCAGCCTTCTGCTGGCGCTTACTTATGAGATGTAGTGTTTCTCTCTCTACAAAAGCTTCTTCAACCTCATGCCTGCTGGTCCATTCGATATCCTTATCGTAGGGGCCTCCGCAGTGGGGGCAGACTTTGTATTTTCTGGTATCAATCTTGCAACCGCAGAAATCACAGGTTATTTCGGGATCAACATATTCAAGTTTTTTTGCCTGTCTTCCTGCAGCCTTTATAACTTCATCCTTGCTAAATGCATTGGCCTTTACCTGAAAATAGCGGAAAATAAGGTAAAAAAGGTAAATGAGTAGTCCAACAATAATATAAAACAAAAACATGATAAGCTAGTTCCTTTGATGTAATAATATTAAGTCTTTATCCGGAGCTCTCGATTAAAACTCACTAAGTTCTGAGGATATCTTTTCCCATTCATCATAAAGAGAAGAGAGTTTATCCTGAATTTCTGTCTGCTCATCAGTGAGCTTACGAAGCTTGGCAAGGTCAGTTCCGACTGATGGATCTGAAAGCTGCTCTGTGATCTCACCGTCCCTGCCTTCAAGTTTGGAAATGTCTTCCTCACATTTACTAAGAGCTGTTTCAAGCTTGCGCTTCTGAGCCTGCAGAGCCTTCTGAGCCTTCCAGTCCATAGCACCGCCTGCGGTAGCATCGGAAGATTGCGCATTTGAAGAAAGAGAAGATGCGCTTTCTGATGCATTGTCAGAATCATTTAAGTCTGCAGCTCCATTTGCGTATTTATAGCTTCCATCTCCAAGAGTGGCATTTCCTATATTCCCGGAAGTACCAAAGAGCCTTTGCATCTTCTCATCGACATGCTCCATGTAGTAGTCGTAGTTACCAATGTAATTTACAAACTGTCCATGTGTAAGATCCAGTATCCTTGTGGCGGTTCTGTTGATGAAATATCTGTCATGGCTGACATAGAGAACAGTTCCGGTGTAGCCTGAAATTGCTGTTTCAAGTATCTCTTTTGAAGTGATATCCAAATGGTTTGTAGGCTCATCAAGAATGAGGAAATTGGCATCAGAGAGCATGAGCTTGGCAAGGCTTACACGTCCCTTTTCACCACCTGACAGATCACCGATGCGCTTGAATACATCATCACCGGTGAACAGGAAAGCAGCCAGAGTATTCCTGATCTCTGTGTTGTTGAGTGTAGGATATGCATCTGATATTTCTTCGAACAAGGTCTTTTCATCGTGGAGAACATGATGTTCCTGATCGTAGTAGCCAATATGAACTTTGACACCAAAATCAATCTGACCGGCATCAAGGCTCTCAACTCCGTTTATTATTTTAAGGAGAGTTGTTTTGCCTGAACCGTTATCACCAATGATTGCGACATGCTCGCCTTTTTTGATCTCAAAATCAAGATTTGAGAAGAGGTGCTCATTACCAAATGACTTGGAAAGCCCGGTTGCAGTCAGAACATCATTACCACTTTCGCAGGAAGGAGTCAGGCTTATCTTCATGCGATCATCAATTGTTATGGGCTTGTCGAGAACTTCTATCTTATCAAGCATCTTTTCACGGCTCTCAGCCCTCCTTATAGATTTTTCTCTGTTGAAGGATTTGAGTTTGGCAATTACTTCTTCCTGATGCTTGATCTCAGCCTGCTGCTTGATGTAGGCATTCCACTCTATAGCTCGCATCTGCTCTTTTTTAACAGCATAGGTACTGTAGTTTCCGGTAAAAGAGGTAACTCTTGTATTCTCAACTTCGATTATCTTGCCTGATATCTTATCAAGGAAATATCTGTCGTGAGAGACAATAAGTACAGCGCCTTTATAGTTGAGAAGATAGTTTTCAAGCCATCTGATAGAGTTCATATCAAGGTGGTTTGTGGGCTCGTCCAGGATGATGAGATCAGGCTTCTGTAGAAGAAGCTTACCAAGAGCAACTCTTGTTTTCTGACCTCCTGAAAGGGTGCTGATCCTCTTATCAAGCTCTTCATCGAGAAAGCCAAGACCCTTGGCAACACCTGTTACTTCGCTTTTCCAGGCATAACCAGATTTACGCTGGAATTCATCCTGCATTCTGGTATATCTGTCCATAAGAGCTTCAAGTTCTGCTCCCTGGACATGCTTCATGTTCTCTTCAGCAAGACGGATATTATTTTCAAGATCTATGACATCTTTTTTTACTTCTACGAGTTCTTCATAAATCGTGTTCTCTGAGTCGATATTCTGGTTCTGAGCAAGATACCCCCAGGTGATATCCTTAGAAAAAGTAACATCCCCATCATCAGCTGATAATTCACCGATTATTATCTTTATAAGTGTAGTCTTACCCGCACCATTTATACCAACGATGGCGGCCTTTTCATCTTTTTCTATATGAAAAGAGGCATTCCTGAGAATATCCTTGCCATCAAACGACTTATTAATGTTATGTACCGAAAGGATCATAATATAAGACTCCCAAATAAGTTTTTTAACACCACATTTTAGCATGTAATTCCCAATCTGTAAAAGAATCAGTTTAGGTGGAAGAAAAGTTTTAAGGTGCGGATTTGGCGGCAGAAATGTGGTATGATGTGGGATGTATGATTTCTGTGGGCAAGAGAGGAATGGCTCACGGGAAGTCGTGAAATATAGTGGGAGATGGAGATTGTATGGAATATATTGTTGTGGTGCTATTTGCTGCGGCGGTGTTTGCTGCGGTCATATTGTATCTTGCATTTAATCAGGAGCAGAGGGAGAGATGGCTTGGCTTTACCTTTGGCATAGCTTCTGTGGGCGGAATAGCTATTTATGGAACGGCACATGCACATGAGGCAACTAACCTTGTGGCTGCAATATTTGAGACAGTAGTTGATGTTGGCAGGATGTTTGCGGGAATTAATAATGTCTCTGCCTTTGAGAAGCTTGTTGGGGCTGATTCCAAGTGGATGATACTGTTCTGGGGCGTTCACTTTCTTGCTTATTATTCTCTTGCCAGTGCCATCATAATGACTGTTGCCAAGGGAATGCTCAAGAAGATCAGAACTTTCTTTTTACATATCAATGATGTCGAGCTGATATATGGAATTACAGATAATTCCCTTTCATATGGCAGAAATATTGCTGATAAAGACCATACTTCAATAGTCTATGTGGGAACCAGTACTAATGGCAAGGAGAGCCAGATCAGCCAGATGGGCGGACTTCTTTTTTCAGATAGCCAGGCTCTAAATCCTGATGCCAAGTTTCTTCAGAGATTGTCTGTAAAGCGCGGTAAGAGTAAGTTCAGGCTCTGCGCTCTGTCCGGAAATATAGATGATAATCTTGAATATGCGGCCAAGATCCTGAGAGCTCTTGAAAAGGCCAAAGTACGTCCGGAGCAGACAGAAGTAATCCTTTATGGCTACGAAGAGCATAACGGAGATATGCTCCAGGCTGTGGGCGATAAATATGGCTATGGAACTGTAAGAGTCTTTGAAAAGGCAGAGCTTCTTGCAAGGCTTCTCATGCAGAAATATCCTATCTGCAATGCGGTTACTTTCGATGAAAATGCAAGGGCAACCTGTGATACCAATGTACTTTTGATAGGCTTTGGCAGAAAGGGACAGGAGCTTCTTGAAAAGATAGTAATAAATGGCCAGTTTGAGGGCAGCAACTTCAAAGTCAAGGTATTTGACAAGAACGGACGTGGAACAGATGGGTTTTTCAGAGCGAGGTTCAGCTCTTTACTGGATAATTATGATATTTCTTTTGAAAATCATGATGGACGCAGCAGAGAACTTGCAGTGTATCTTGAAGAGAACATCGATAAACTTAAGTATATAGCTGTAGCTGTAGGAGATGACCGCACAGGACGTGAAATAGCCATGAATATCCTTGAGTTTATGAGAGGAAGAGGCGCTTCGCTCCCTGTTTATCAGTGCTGTAATGACTGCGTGGCTAAATATGAACTTAACAGCCTTGTTGAGAGATATAGTATTTTTGATGCTAATATTCTCTATAACGGAATGATGGATGATCTGGCTAAAAAGCTTAATCATTATTACATGAACAACAGCGCTTCTGCTAAAAAGAACTGGGCAGACTGTAACTATTTTGACAGGATGAGTTCGAGAGCTTCAGCGGACTATCAGGCTGCGCTTTTAAACAGGCTCGGGCTATGTAATGGCCAGGAATTACCGGCTGAAATTCTGGAAAACCTTGCTAAATCTGAGCATCTTAGATGGAATGCTTTTTATTATGCGTCAGGCTATAAGAAGATGGATATTGAGACCTTTAAAAAGAGGGCGAGGAATGCACAGACATCCGGGAATAAGCGAGTATCCAAAGATGCTGAGGGCAAGAGGCATGTATGCCTTGTGACCTGGGATGAGCTTGATGAGATTTCTGATATTGAGAATAGTATTATGGGAAAAGATATAGATTATAAGCAGAAAGACCGGGATAATGTGCTTGTTATCAAAGGACTCCTTGAAAAATAAGAGCCTGACTTATATAATATATGAGATGTGGATTCACAATAAAGGAGTTTGCTTTGAGACGTTTATATATACCACTAGTTTGGGAGCTGCTTTTTGTTATCTCGACAATTATTTTGCCGATGCAGGCTTTTCATCTGTTTTTTGTTTTTTATCTGGGCTTGCTTATTTATTTTTATTATTTTCACAAGCAGTTTTCATTCCGCAAATTTGCACGTAATCTTAGCAGAATAAAGAGATTTTGGATTCCCGTTATTTTGACTTTTGCAGGCCTGATGCTTGCTAATGATATCAAGAATAGACTGATCCAGCCGTATTTTGCGACAGTCAGGGACGGGACAGTCAGTATCATTACGCGTAATGATATTTTGCCAACATTTTTTTATGCACTTATGATGATAGTCATGAAGCCTGTGGCAGAGGAACTGTTCTTTAGGAAAGCCATTATTTCTTTTGGCAGTAAGAAAAGAGTGTTTGTACTTACTCTTGTGAGCCTTATTTTATGCGCAGTTACAAGAGCGCACGGGGTACTGGGAATAGCTGAATGGATCTTAATGGCGATTCCGGTTACGATTGCTTATGTTGCTACGAGAAATATTTATATTTCGGTAATGGCTCATGTGGCCTTTGAGTTTTATGACAATATATATTCTATTGTTTATGCTGTAGGCAGGATAATGAATAGATAGTTTATTAAGGTTTATGGTATAATACAAGCCGGTATGTTTCTGATAGAAATATGCCGGCTTTTTTGGATAGATCAACTATTCAGCACATATATTTATAAGGAGAAGAGGTATGTTAGGAAAAAGAGGTAATGCGCCCAAGGCCAAGGCTAATCCCAAGCTGATAATAGTAATTGTTATCGCCGTTTTAGCTCTTTTGTGCGTGGGGGAGAGTTTTTATTCTGTTAGGGAACAGGAACAGGCTGTTCTCACAATGTTTGGTAAGGTGCTCAGAGTTGACACTGCCGGACTCTATTTTAAAATCCCATTTATTCAGGATGTGCATACTATAGATATGACAACTCATGGTGTGGGTATCGGATACTATATCAAGGATGGACAGAATATCACTGTTGATGATGAGGGAGTGATGATCACTTCTGACTTTAATTTTGTAGATATTGATTTCTATCTGGAGTATAAGGTAAGTGATCCTGTGGCATTTTATTATAATTCTTCCAATCCGGAAGTTATTATGAAGAATATGGCACTTGCCTGCATCAGAAATACTGTGGTTAATTACACAGTTGATGATGTTATTACTACTGCCAAAGGCCAGATCCAGGCTGAGGTTAAAGAGAAACTTCAGAATGAGCTCACAAACAGCAATATCGGTATGATGGTAGTTAACCTCTCTGTTCAGGATGCAGAACCACCGACAGAGGAAATCGTTCAGGCTTTCAAGTCTGTAGAAACAGCCAAGCAGGGCAAGGATACAGCAGTTAATAATGCCAAGAAGTATCAGAGCGAGGAGCTTCCCAAGGCAGAAGCTGATGCTGATAAGATCGTTCAGGATGCTGAAGCTTACAAGCAGGCCAGAATAGCAGAGGCAGAAGGTCAGGTTGCCAGATTTAATGAGATGTATGAGCAGTACAAGCTTCAGCCATACATCACCAAGAAGAGATTATTCTATGAGACTATGGAAGAAGTTCTTCCTGATCTTAAGGTTATCATCACTGATGGAAATACTCAGCAGATGCTGCCTTTGGATAACTTTAACGGTAATGATTGATGGAGGCCTGATATGGAAAAGAAGAGATTTGGTTTTGGAAAAATATTAGTAATAATTGTACTGCTCGTTGCTGCTTTTCTTGTTGGCTCATCAATGTATGTGGTTCATCAGAATGAGTATGTAGCAGTAAGAAGATTCGGTAAGATCATTGCAATCGCTTCAGAACCCGGACTTCACTTTAAGACACCTTTTATTGAGGATACACAGTCAATCAGTGGTAAGATCATTATTTATGATATTCCTGCATCTGACGTTATCACCAAGGACAAGAAATCTATGATCACAGATACTTATGTTCTTTGGAGAGTATCAGATCCGCTTAAATATATTCAGACTCTTAATGCTGTAAGTGCAAGAGCTGATGAGAGAATAGAAGCTTCTGTCTACAATGCTACCAAGAATGCTATTTCATCTATGAGCCAGGATGAGGTTATCGAGGCAAGAGGAGAAACTCTTACCAAGCTGATCACAGAGGAGGCAAACTCTGATATGGCCGGATATGGTATTTCTATCATACAGGCTCAGATCAAGGCCCTTGATCTTCCTGATGACAACAAGCAGGCTGTTTATGAGAGAATGATCTCAGAGCGTAATAACATTGCAGCATCCTATACAGCACAGGGAGCTGCTGAAGCTCAGAAGATCCACAATGAGACTGACAAGCAGGTTGCAATCGTCAAGGCTCAGGCGCAGAAGAGCGCTGCTGTCCTTGAGGCAGAGGGAGAGGCTGCTTACATGGAGACTCTTTCCAAGGCTTATGACACAGAGGAAAAGGCAGAGTTTTACAGCTATATCAGAGGACTTGATACTCTCAAGGAATCACTTAAGGGAGAGAAGACTATCATCCTTGATAAGAACTCTGAGCTTGCTCAGATCCTATATGGTAACTTCAATTGAAACCTAAATAGAATCACCAGTGTTTGTTTGACATTTGCCCCTAAAGTGTGCTTTAATAGTTTAAACTGTTGAAGATAATCTGGGGGGAGAACAACAAATATGAAATTATGACCTGTCCCAACATGCAGTTGTTGAGACAGGTTTTCTTTTTGCCTACCTCAAACAGAATAATAGAATTATTGAAAGGTCGTGTATTATGAGTGAAGAAATGAAGATTCCTTACAAAATTTATCTTAGCGAAGATGAGATACCCAGGCAGTGGTACAATGTCAGAGCTGATATGAAGAATAAACCGGCTCCACTTCTCAACCCGGCTACTCTCAAACCTATGACTTTTGATGATTTGAGACCTGTGTTCTGTGATGAGCTGATCAAGCAGGAGCTTGATGATACAACTCCTTATATTGATATTCCTGATGAAGTCATGGACTTTTACAGAATGTACAGACCGGCGCCTTTAGTAAGAGCATATTTCCTTGAGAAGGCACTTGGAACACCGGCCAAGATTTATTATAAATTTGAGGGTAATAATACAAGTGGCAGCCATAAGCTTAATTCTGCTATCGTTCAGGCATATTATGCCAAGAAGCAGGGACTTAAAGGCGTTACTACAGAAACCGGTGCCGGCCAGTGGGGAACAGCTTTGTCTATGGCTTCAGCCTATTTTGGAATAGACTGTAAGGTTTATATGGTTAAGGTTTCATATGAGCAGAAACCATTCAGAAGAGAAGTAATGCGTACTTATGGAGCCAGCGTAACTCCTTCACCTTCAATGGATACTGAGATAGGACGCAAGATAAATGCTGAGCATCCGGGAACTACAGGAAGTCTTGGCTGTGCAATTTCCGAGGCAGTTGAGGTTGCTACCAAGACTGAAGGCTACAGATATGTACTTGGAAGCGTGCTCAATCAGGTGCTTCTTCATCAGACCGTAATAGGTCTTGAAGCTAAGGCTGCACTTGATAAGTATGGCGTTAAGCCTGATATTATCATTGGATGCGCCGGCGGCGGATCAAACCTTGGAGGACTTATTTCTCCGTTCATGGGAGAAAAGCTCCGTGGAGAAGCTGATTACAGAATAATTGCTGTAGAGCCTGCAAGCTGCCCGTCTCTTACAAGGGGTAAGTTTGCTTATGATTTCTGCGATACCGGTATGGTGTGTCCTCTTGCCAAGATGTACACACTTGGAAGTAACTTTATTCCTTCTGCTAATCATGCGGGCGGTCTTCGCTATCATGGCATGAGCCCGATTCTTTCCCAGCTTTATGATGATGGCCTTATGGAAGCAAGATCAGTTGAGCAGACTTCAGTATTTGAGGCTGCTCAGCAGTTTGCGAGAGTTGAAGGAATCCTTCCGGCTCCCGAGTCAAGTCATGCAATCAGAGCAGCTATCGATGAAGCTCTTAAGTGCAAGGAGACAGGTGAGGAAAAGACAATTCTCTTTGGACTTACAGGTACTGGCTACTTTGATATGGTTGCTTATCAGAAGTTCAACGATGGAGTCATGATGGACTACATTCCTACAGATGCTGAGCTTCAGAAGAGCTTTGATACACTTCCCAAGATCAATCTTTGATTTATATAAGGTGGTTTTGTTTGATACTATTTTGACAGGAGATTTTGACATGAATATTGTATGTTTGGACTTAGAGGGTGTACTTGTTCCTGAAATATGGATTGCATTTTCTGAGGCTAGTGGAATTCCCGAGCTTAAGAAGACTACACGAGATGAACCTGATTATGACAAGCTTATGAAATGGAGAATAGGTATTCTCAAAGAGCATGGACTTGGACTTAAGGAGATACAGGATACTATCAAAAAGATAGATCCTCTTCCGGGGGCAAAAGAGTTTCTGGATGAGCTTAGAAAGATCACTCAGGTCATTATCATAAGTGATACATTTACTCAGTTTGCAACTCCTCTTATGGAGAAGCTTGGATGGCCTACTATTTTCTGCAATTCTCTTGAAGTTGCAGATAACGGTGAGATCACAGGCTTTAAGATGAGGATAGAGCAGTCCAAACTTACAACTGTTAAGGCTCTTCAGTCTATAGGTTATGAAACCATCGCAAGCGGAGACAGTTACAACGATCTTGCAATGATACAGGCATCCAAGGCAGGCTTTTTATTCAGATCAACTGATAAGATCAAGGCTGACTATCCGGAGCTTCCAGCTTTCGAAGAGTATGATGATCTTCTTGCAGCTATTAAAAATAACCTATAAATTGTTCAAAAATGACTCCTGCAAGTACTATCTTACAGATGTATAATAAATCTATAATAGAATTATTTAGGAGAGTTTATAGAAATGAAAGATTGTAACTGCGGATATTGTGTAGGTGGTGAGCCACTTGCCAAGTTTGGAATCAAGATTTGCGACCTGGAAGTGAGTCAGCTTATTCTTTTTAAAGAGCAGTCTCATCCGGGCAGATGTATAGTAGCATACAAGGATCATGTCAGTGAGATAGTTGATATATCTGATGCTGACAGAAATGCATTTTTTGCAGACGTTAATCGTGCCGCCAAGGCTATTCACAAGGCATTTAATCCTGATAAGGTTAACTATGGTGCTTATGGCGATACTGGATGTCATCTTCATATGCACCTTGTGCCTAAGTATAAGGACGAATTCGAGTGGGGCGGAGTTTTTGAGATGAACCCACAAAAGGTATTCTTATCTGATTCAGAATATGCTGAAATGATTGAGAAGATCAAGGCTGCACTTTGATATTGGTATCATTTGCTTGCTGCTATAGGCTTTTAGCTGTTTTACAATAAGTTTTTTAGAGGAGCTGTCGCACACTAAGATTTGATCATTATTTGATCATCTGGAGCGACAGCCCTTTTTTGCGTTATAATTAAGTTAATGGAAAGAAGCTTTTCTAAAATGAGGAGTAATAATGGCTAATATAATCAATTATATTAAGTGGCGTGGCGACCTTGAATTTGAAAAAGTTCCCTTTAATAAGGTTGATAATCTTGGGCTTACCATGCTTATTTATAATGATTTTTCCGGTATAGTTCCTGGCAAAGATGAATATGGCCGAATTTCTATCAGGGAAGCTGCAGATAAGTATTTTCAGACTCATAGTCTTGAAGGACTTGATAAGTATGCCTTTGACTGGGTTTTATACTACATGGGGAAGTACAAACGTTTTGGAAATCTGTATTTATCCGATTATGTGGATGTGAACGACACTGACAGAAATATGGTGTTTACAGCTTTTACTGTTCATCTTCCGGATGGAAGTCATTTTGTCGCATATCGCGGAACGACAATGGAAATTGATGACTGGAGACTGGATTTCCAGATCAGTTTTGAAGAAATAGAGGCGCAGAGGGCGGCAGCGAGATACCTTCAATATGTTATGAGCAAGTACGCAGGAGATATATACGTAGGTGGGCACTCAAAAGGCGGCAATCTGGCTGTTTATGCATCTATGAATTCTTCTTCTGAGGTCAGAAACAGAATTAAAAAGATATATAGTTTTGATGGCCCTGGTTTTTGCCCCGAGCTTTTAGAGAAAGATAAATTTAACGAGATAAAAGAGAGAATCGTACATATAGTACCGGCATTCTGCGTAGTTGGAATGTTGTTCGAACTTCAGGTTCCCCATGAAATTGTAGCATCCAGTGCTTCTAAAATAGCCCAGCATTCAGGTATGACCTGGAAAATAGAAGGAAATCACTTTGTTCATAGAAGATTTCTCACTGATGAAAGTACAGTCTATAACAATGCCATCGATGACTGGATTGGAAATGCGACAATGGAGCAGAGAAGGGCGTTTACCAGAGATATCTTTGATGCGATGAAGGCAGGAGGAGCTGTTAACATTAACGAAATCTCAGAAGGCGGATTCCACGATTTTGGAACGATCCTTTTATCGGCAGCCAATTCAGAGAGTAAGACCAAGATAGTTGTAGGTAAGTTTTTTGGCTCCCTTTGGAGATCATTTGAGAAAATCAAGATTTTAGATGCTGTTAAATCTCTTCAGGGTATTATAGATCTCTTTCTTATATTTGTTGGTATTATCTTTTTGACTATTCCGCAGGCAGTTTATAGTGTTCTTGGCGGAGCTATAGCGCTTGTAGTTGCCATTTGGAGTGCTGTTATGCTTGTTAAGGCGGGAGTTAGAGATGAAAATCCATTTATAAAACGGGGAAGAATGATATTCCACATTATTATTATGTGGTTTATGGTCTTTATCATGTCTAACCTAGAGAGAATACCGAAATGGACTAATCTGCTGATGGCAATAGTATTCTTTTCTCTGGCTTTTGCCAGTGTGAGGTACATTATAAAATATAAGACAACAATTTCAGGAAAAGCCAAGTTTTGGATGATGCTCCTGGCGGTTGTTAATGTTTACATTGGTATTATTGCGATTGTAATGCCGGATAGATTTGGCATTACTAAATCAGTAACACTGGGAAGCTATCTTATAATTATTGGATTTATAAGGCTTATAATCCAGCTTCTGGAACAGATGCAGAATCCAAAGAGTGATGGCAGATTTTATGAAGATGAGGAAGAAAAATAAAACAGGGCTCTTCACATATGATCGTGAAGAGCCCTGAAACATTTTAGGCGTTAAGTTCCTTACCTGTAAGAAGCTTGTAAGCTTCGTGATATTTATCAATAGTCTTATCGATGACATCCTGAGGAAGATTGTAGTCACATTCAGGATGAGCCTTTAAGTAGTTACGTACAAACTGCTTGTCAAAGGATGGCTGATCGTGACCTGGCTCGTAACCTTCTACAGGCCAGAAACGTGAGCTGTCAGGTGTGAGCATTTCATCTGCAAGAACTACTTCACCGTTCTCATCTACGCCAAACTCAAACTTGGTATCTGCGATGATGATACCACGAGTGAGAGCGTAGTCAGCACATTTTTTGTAAAGAGCAATTGTGTAATCTCTGATCTTGGTAGCATAGTATTCACCGTGACCTGGGAACTCTTTTTCAAGAACCTCGATGCTACGCTCGAAATCGATGTTCTCATCGTGATCACCGATTTCTGCCTTGGTACTAGGTGTGTAAATTGGTTCAGGAAGCTTATCGCATTCCTGTAATCCCTCAGGAAGCTTGATGCCACATACTGTGCCATTTTCCTGATAACTCTTCCAACCACTACCTGTAATATAGCCGCGAACAATACATTCAACTGGTATCATTCTCAGCTTCTTGCAAAGCATGCTGTTACCGGTAAAATCTGGTGTTCTGAAAAACTCTGGCATGTCGTTTGTATCAACGCTTACCATGTGGTTTTTTACCACATCTTTGGTATAGTCGAACCAAAACTTGGACATCTGTGTTAATACTGCGCCTTTGGTAGATACTTTGTTCTTAAGGATTACATCAAAGGCTGAAATTCTGTCGGTAGCAACCATGATAAGGTTCTCGCCTACATCATAGATCTCTCGAACTTTTCCTTCTTTTACTGGCTTAAATTCCTGCATGCTCATACTCCTCCATAGATATAAAAAATATATTTATTGTCACGGATATGATCCGTAAACTACAAGGTGATCTGCATGATCAGGCTGCGGTGGAAATGGCCTGACATGCGAAAGTATCAGTCGTCTTCCTCTTCGTCAGTAGCAGTGTTATAAACTGTACGCTTTCTGGCCATTTCATCATTTTCAAGGTACTCATCGTATGTAGAACGCTTGTCGATAAGTGATCCGTCAGGGAGAATCTCCATGATTCTGTTGGCTGTTGTCTGAACAACCTGATGGTCACGACAAGCAAAAAGCTCTACACCTGGGAATTTGATCATTCCGTCGTTTAGTGCGGAGATTGATTCCATATCAAGATGGTTAGTAGGCTCATCAAAGATAAGACAGTTTGCACCGCTTATCATCATCTTGGAAAGAAGGCAACGAACCTTCTCACCACCGGAGAGAACCTTAACCTTTTTAACTCCGTCTTCTCCTGCGAACAGCATACGTCCAAGGAATCCTCTTACGTATGTTGCATCCTTAATCTCAGAGTAGCCTGTGAGCCACTCGGTAATTGTGTAATCATTATCGAACTCTTTGGTGTTGTCCTTGGGGAAGTAAGCCTGAGATGTTGTAACACCCCATTTGTAAGTTCCCTCGTCAGGCTCAATCTCTCCTGTGAGAATCTGGAAGAGAGTAGTCTTGGCAAGCTCGTTGCCGCCTACGAATGCGATCTTGTCATCGCGCTGAACAACAAAAGATACGTTATCAAGAACCTTCTCACCATTGATTGTCTTGGAGATACCATCAACGGTAAGGACTTCGTTACCAATCTCTCTGTCTGGTCTGAAGTCAATGTATGGATATTTACGGCTGGATGGTTTGATTGTATCAAGCTCGATCTTCTCAAGAGCTTTCTTTCTGGAAGTAGCCTGCTTACTCTTACTTGCGTTAGCGGAGAAACGGGCAATGAATTCCTTGAGCTCTTTGATTTGTTCCTCTTTCTTCTTGTTGGCTTCCTTCATCTGACGGATCATCAGCTGTGATGACTCGTACCAGAAATCATAGTTACCGGCATAGAGCTGAATCTTGCCATAATCTATATCTGCAATATAAGTGCAAACCTTGTTGAGGAAATAACGGTCATGAGAAACGACGATGACTGTGTTCTCAAAGTTGATAAGGAACTCCTCAAGCCAGGCAATAGCGTCAAGATCAAGGTGGTTAGTAGGCTCATCCAGAAGAAGAATATCAGGATTACCAAAGAGTGCTCTTGCAAGCAAAACCTTGACCTTCTGGGCACCATCGAGCTCTTTCATAAGTTTGTAGTGGTATTCTGTATCGATTCCAAGTCCGTTAAGAAGAGACTCTGCATCTGATTCAGCTTCCCAACCATTCATCTCGGCAAATTCAGCCTCGAGCTCACTTGCTCTGATACCGTCTTCATCGGTGAAATCTTCCTTGGCGTATATTGCATCTTTCTCATTCTTGATCTCGAAGAGACGCGCATTACCGGCGATAACAGTATCAAGTACAACATTATCGTCATATTTGAAGTGATCCTGTTCAAGGAATGATAAACGCTCACCATCTGAAATAACTACATCACCATTTGTTGTCTCAATCTGTCCTGACAAAATCTTGAGAAATGTAGATTTACCGGCACCGTTTGCTCCGATGATACCGTAGCAGTTACCGGGAGTGAACTTGATGTTAACTTCTTCAAAAAGAGCTTTCTTACCAACTCTTAAGGTTACGTTATTTGCACTAATCATTAAAAAATAACCTCACAATTTAATTAAAATCTATCCTTTGCAACAGTTCGTATTATATGAGAATCTTCTATTAATTGCAACCAAAAAAGATACGTACTTATTTGAGGGCAATATGAGCGAAAATGGGAAGAAAGGGAAGAAAACTGAGTTTAAAATCATTTTCAAAGAGTTTATATTTGACTTGTAATGATTTTAAGACTAATGACCGGGGGAAAATATGTCACTTCTTGATGATAAAGTAAACACAGTTTGCGTTCAGGACACAGACTCATATAAGGCACTTTTAAATGGCGGATGGAATAAAAGAAGACTTATTAATAAAGACTCTATTTGCAAAGATAATAGAAACAGAAATGTAGTAATAAAAGAGTATGAAGTATCAGAATTTGGTACTTATAGGGTAGAGGTATCTATTCTGGCAGGCTCAAAAGGCTTTTTTGACCTTACGCTATTTGCGGGCAGAAGGAATATGATAGCCCGTAATATAGATATTAAGGCTTCTTCAAAGTACCATAAAGTTTTTTATCAGGCTGTATTCCCATACATTCCTGCGCTTACAGCAGAGAGATTAAACGATAAAAAAATATATATAAGTGTTGCCGGTATTGATGAAGCTGATGCAGATGGGGCACTGAAAGTTAAGATAACAAAAGAAGATGTTCCTGTTATATGGGTAGCGGGAGACTCCACTCTTACTGATCAGAATGCCGGAATTCCTTATTATCCTTATGCCAGCTGCGCCGGTTGGGCACAGACAATCAGCAGATATATAAGAAATGCTGCAGTATGTAATCTTTCCCATTCGGGAATGACATCAAATTGCTTTAGAGATGATGGCCATTATGATATATGCCGCGAATATATGAAAAAAGGTGATCTTTTTATCATTCAGTTTGGACACAATGATCAGAAACGCAGGAATTTAGCCGCTTTTGGAGGGTATGCTGACAATCTGAAAAGATACGTAAACGAAGTAAGAAAAAAAGGAGCAGAGCCTGTGATCTGTTCGCCTATCAGCCGTATTCCGCTTAAACTCTCAGAAGAAGAGAAAAGACACCTCGGTATGCCTATGCATTATTCTCTTTTACAGGCACATGCTGATGCTGCTAAGGAAGTGGCAAGAAATCTTAATGTGCGATTTGTTGATCTTCATAAGTTCTCTATGGACAGATGGATTCTATTTGGCGATAAAGCCAAAGATTATTTTATGCCCGGGGATATTACCCATACCAATGAGTATGGAGCTGTAATGATCGCAGATTTCTTTATGTCTGAAGTAAGAGACATGATTGATGAAGAGATGATTGAAAATACAGCTTTTAGTCCTGACCTTGATGTAAAAGAGATTCCCAAGGAAATACCGGGACCGGGCATTTTTGATATAGAGCCTCCTTATCTTGATATAAAGGACAATCCTTATTACGAGGGAATCAGAAAAGCTTTCAGATATGCCCTTCTAGATCCGTGCGTAATGTATCTTCATCCGGATGATTGCATGCCAAGAGGACAGCTTCTTATGGTGATGTTTAATGCTTTTAGAATGGCCGGAATACGTCCCTATAAAAAGAAATTTCCGGATGTTCAGGTTGATGAATGGATTTCAGGATATGTACAGGCGCTTATTGAAAATGACCTGATAGATTACAGAACGTATTCCTCTGAAAAAAGAGATGGAACTGAGAGCGAGACAATTTATTATTTCAGACCGGATGATCCGCTTACTTATGAAGAATTATCGCAGTTTCTTGTCCTTAAGCTTGAGCATGATAAGAAAGAGTGCTATACCAAAAGAGCTTGTGAATTAGGATTTATAGACATTGACCTGAATGATAAGGATAAAGAGATCAGTAGAGCAGAGGTGTACACAGTACTCACAAGATATATGGACAAGGTGAAACTGGCTGATGAGAGCCTTCCGTCTGATGCAGAGGTACATCCTGTGCACTGAGTGATGCCGTATCTGCGAGTAGAACAGCTTTCTGAAATACTGGATTTAAGAAAATGTAGTATTGAAACATAACAAATGATATAATGATAATAAGTATGTGAGATGCTACATCTGTAGCAGTTTGTGATTCTCTACAAATTTTGGAGGCAACTCATGGCGTTTGGCTCAAATAAGATACTGGTTATCGGCGAAAAGGAAACATTCATCATCAAGGTTCTTCTTGGTAAGCTCAAGGATGCCGGGATTACAGCTCTTTTTTCAAAAGCTGATGTTAATGATATTAACGAGGAATGGGGCGATAGCGGCCTTATAATCTATTATCTTGAGGCTGGAGAGCGTATGGATGGTGATGTGGCGACATTTCTTCGCGACAAGCTCTCTGATAATAATAAACAGCTTGCTCTTATAGGTGATGCGGCTAATACCAAGGAGATAATAGATAGTTTTCCTCCACACATTATTTATAAGACTTTTTCAAGACCTATAGACTACAATGCATTTATATCTGATGTCGGCCTGTATTTTAACATGGTGGCAGAGGGTGAGATGAAAAAGAGTATTCTGATAGTAGATGATGATCCTAACTATATGGGTCTTGTGCGTGAATGGATCAAAGATACTTATAAGGTTTCGATGGCCAATTCGGGTCTTAGAGCTATTAAGTGGCTTGGCAGTAACAAGGTTGATCTTATTCTTTTGGACTACGAGATGCCGGTTACTGATGGCCCGCAGGTCCTTGAAATGCTCAGAAGTGATGATGAAACTAAGGGTATTCCTGTAATATTCCTTACAGGTAAGGATGATAAAGAAAGTGTTATGAGCGTACTTGCCCTTAAACCTGAAGGTTACATACTTAAGACAAGTGGCAAAGCTGAGATAGTAAATACTATCAGCAAATTCTTTGTAAACAGATAAATATTTATACACGGGACGGATTGTTCGATGACAGATGATGGAATAGAAGTTCCTGAGGAATTAAAAAAGCTTGAGAATATAGATGGTTTATCCATATCTGAGGGGCTGTATTATTGTGGCAGTTCCAAAGCCTATATCAAATTTCTCAATACTTTTTTTCATACGATAGATAACAGGGTACAAGAAATAAAAGAGTCTCTGGAAAGAGACGATATAAATACTTATACGATCAAAGTGCATTCTCTAAAGAGTACTTCCAGAATTATTGGGGCAGGAGAGCTTTCAAACTTTGCTCTTAGCCTTGAAGAGGCAGGAGAAAGAGGCGACAGGAAATTTATATCTGAGAATAATGATAAATTCCTGCAATTATATATATCCTACAGGAATAAGCTGGCTGCCTTTTTTGAGAATACTATTGATACCAGAAAAGAAATATCTGCCGATATGCTATCAGATGCATACAGTGCACTTAGAGAAGTAGTTCCTTCAATGGATTATGATGCGGTAGAAATGATAATTGGAGGACTCAGAGAGTACAAGATCCCTGCTGCTGACAAGGAGAAAATTGACAGGATAGCAAGTCTCCTTGAACAACTTAAATGGGATGAAATAGCACAATTATTGGATTAATAAAAGCTGAGAGACTAAATATCTCTCAGCTTTTTTATTATCATCGTTCATTGCCCCAGAAGAATAATCCAAGCATACCGGGGCCTACGTGAGAACCTGAGAATGGTTCGTGCATGCAGATCGTAACCTGAGCTCTTGGATTTATCTCTTTAACCATATCAGCAAGCTTATTGGCGTCATCGAGGCAGTCACCATGTGAAATAAATACGATTTGTTTCTCATCCTCCATTCGCTTTTCTGCGTATTTTTTGGCAAGCTCAGAGATGGCGTTCTTACGACCTCTGACCTTATTACATGAGATAATATGGCCTGTGCTGTCACCAAAGAGAATAGGCTTGATATTGAGAATAGTACCAATATTGGCTGTAACTCCGCTGACACGTCCTGTGCGTTTAAGAAAGTTAAGATCATCAACAGTAAAGTACTGACAAGCATGTGGGACAGCTTCATCGAGGATGTCGGCAGCATTTCTGGCATTTACATTTTTTCTGGCAAGATCAACAGCCTTAAGAGCTAGAATACCGTTTCCAAAGCCGCAGCCATGTGAATCAACAATATGTATGAAACAGTCAGGATATTCTTCCATAAGCTCGTCTGCAGCGATTCTGGCAGCATTGTAGGTTCCGCTGATACCTGAACTCATGGAGATATAAATAATATCCTTGCCTTCCTGAGCATACGGAGTGAAGTGTTCGATGAATAACTGAGTATTCAAAAGACTTGTCTGAATAAGATCTCCGTTTCTGAGACCTTCATAGTATGTATGGCCGTCGAAGTTATCTATATCGCCGCTGTAAACCTTCTGAGTACCATTAACAAGGTAATTACAAGGCAGAATAACAATCTCACTGGCTATTTTTTGTGGTAAATTTGCGCATCCATCTGCGAATACAGTAAAAGACATAAAAAACCCCTTAACTTTTTCAAAATAATGTACAAAGGTAATTATATCATACTTTATTTTGTAGTAGTATTACATTATAAGAATCAAGGGGGTTGGGGTATGAAATTAAACACAAAAAGAACTATTCTTATCGGCTTTGCATTTATGTCAATTTGCGCTTTCTGGCAATTCTATGACAACGAAATTCCAAAGATACTCAAATACTCGTTTAATTTGGGTGAAACACTGACCGGTGTGGTTATGGCACTTGATAATGTGCTGGCACTTTTTCTTTTGCCTGTTTTCGGAACTGTTTCTGATGGAACAGAGACAAGATTTGGTAAAAGAATGCCATATATCGTTGTAGGAACAATTCTTTCTACGATTTTGCTTACAATTCTTATTACAGTGGCAAGACCAAGTGGAAGCCTTGCACTTTTTGTTGGTGTGCTTTTGCTGCTTCTTATTTCCATGGGTATTTACAGATCTCCTGCAGTTTCACTTATGCCTGATCTAACGCCGGCTCCTTGCAGAAGCTCAGCCAATGCTGTGATCAACCTTATGGGAACTATAGGTGGAATCTATATTCTTGTGATGATAAAGGTTTTGCTAAAAGAGGCAGATGATCCAGCCAGAACAAATTATATTCCGCTGATGCTGAGCCTTGTTTTATTCATGCTGATCTCTATAGCTGTTGTCTTTTTTGCAATAAAAGAAAACAGGATCAAAGAGGAAATACATAAAGAGGGAGGCTTACATTCCCTTGGAGATACTTTTGATGATGAAAAGGATGCAGAATGCCTTAAAAACAAGGAACTATTTGAGGAGGGCTCTGTTACCAAGAAAATGCCACAAGAGGTTAAAAGAAGCCTTATATTTTTGCTGGCATCCGTATTCTTGTGGTTTACAGCTTACAATGCGGTAACGACAGCTTTTTCAAGATTTGTCGGCGAAGTGTGGGATCTTCATGACAATGCTTATGCTACATGCCTTTTGGTTGCAACTATAGCAGCTACTCTGAGCTATGTGCCTATTGCCTTAGTATCATCCAAAATAGGTAGAAAGAAGACTATCCTTATTGGTATTTCTATTATGGCTGCCAGCTACGTTATCACCGGATTGTATCCGCATTTTTCACCTTCGATCAACATCTTTTTTGCCCTGGTAGGTATAGGCTGGGCAGCTATAAATGTCAATTCCTATCCGATGGTTGTTGAGATGAGTAAGGCAGGGGATATAGGAAAATTCACAGGAACCTACTATACATTTTCTATGGCGGCACAGGTATTTACGCCTATATTCTCGGGATTTTTGCTTGAACACGTTTCTTACAGAACTCTTTTTCCATATGCCTTTATTTTCTCAGCCCTTGCTTTTTGTACAATGCTGATGGTCAAGCATGGAGATGTTAAGCCACCTAAAAAGGAGCGGATAATAGAAAACTTTGATGTGGATGACTGATGATATATTATAGTCGAATATGCACAAATATGGCGGGACAAAGGAGTGTCCCGCCATTATTTTTGTGTTACGATTATGTGGCAATAAAACTAGTGGTATACATATAAGTGGGGTAGAGCTGTGATCACATACAATACAAATATCATAAACATTCCTGTAAAAAAATCTGTGATGCTTGCTGCAGATTCATTAAAAAGGGATATCCAAAATACATGCCTTAAATCAGATGAAAAGGGGAGTACTATTTCTTTTTCCGAGGATCCTTGTATAGAAAAAGAATGCTTTGTTATCTGTTATGGATCGGATGAACTAAAGATAAGCGCATCAGACGATCTTGGTTTTATTTATGGAATCTATTATATAAGCAAGGTTTTCCTTGGTGTACATGAATTCTGGTTTTGGAACGAACAGAAATTTATCCAAAGAACAGGGTATGAGATTCCGGAAGGCTATCGCTATGCTTCAAAACCGTATGCGGTAAGATTTCGCGGATGGTTCATAAATGATGAAGTACTGTTTGATGGCTGGAAAAAAGATAAAGATGACAACAGGCCCTGGGAGATGGCTTTTGAGACCCTTCTTCGTTTAGGCGGGAATATGACTATTCCGGGCACTGACTTTAATGCTCATATTTACAAAAAGCTGGCGTCTGACTATGGGTTATGGATAACACATCACCATGCTGAGCCTTTGGGGGCAAGAATGTTTGCCAGAGCCTATCCTGAACTTGAGGCTTCATATGATAAATATCCTGAATTATTTGAGAATTTGTGGAGAGAGGCTATTGATGATCAGAAGGATTGTAAGGTCATCTGGAATCTGGGATTTCGAGGCCAGGGAGACAGACCCTTCTGGGCGGATGATCCTGCCTATGATTCAGACGAAAAGCGCGGGGCTCTTATGAGCAGATTGATACGAAGGCAGTATGATCTTGTCAAGGAAATGGACAGTAATGCGGTCTGCTGCAGCAATCTGTATGGTGAGACTATGGAACTATACCAGAAAGGCCTGCTTGATATTCCTGAGGATGTGATCTTTATCTGGGCAGATAATGGCTTTGGCAAGATGGTATCAAGGAGGCAGGGAAGGCATAATCCAAGAGTTTATGCGCTTCCGGAAAAGGGGGCTGAAGGAATGCATGGAATATACTATCATGCTTCTTTTTACGATCTTCAGGCGGCAGCCCAGATGACAATGCTTCCAAATTCGCCTGAATTTGTGGTAAAAGAGCTGATGGATGTATATGACAAAAAAGCAGATGATTTTTGGATAATTAATTGCTCAAATGTCAAACCGCATGCATATATGCTTGATCTTATTGCAAGGATGTGGAAGAAACCCTTTGGAAACATAGATGCTGAAGGTGATGCAGATATCAGCTTATATGTAAATGCACATTTAAGTGATTATTGCAGGGAATATTATGGAGAAGAAGAGGACACTTTGGCATCTATTATGGAGCTTTACCGGAAATGGTCTTCCTATTGTCCATTCTATGGCCCTAATGAGGACGACCACGCAGGAGAGCAGTTTACCAATCATGGGACCAGAGTCCTTGTTACAGGGCTTATCACGAATTATGCTAAGAAGAACCCGGGCTCAACTCCTGCTGCGACCGAATGGTTATGGTTTTCTGATAAAGAAACCTTAAGAGAGCAACTATTGGACTACAGAGAAATAATAGAACCTGCGCAGAGAGGGTATGAGGAATATCTGGTGAAATGCAGGCAGGTTCTTGGAAGCCTAAGTGAGTATACCAGACAGGTTTTGGAGGATACTCTTATATGGCAGATTGAATATCATTATTACAGCTACCTTGGCGCCCTACACGCCATAAGAGCTATTGACAGCATTATTTCTTCGCAGCAGCCTGCGGATACAGATTATCTGGATGCTTTTTACGAGGCAGGTCTTTCTGCAAAAGCTTTTAAAAATGGCTATGATAAAATGCGCAGCCATGAACACGGCGTTTTTGAAGGCTTTTTTGACAACGACTGTGAAGCTGACATCAGGCAGTCCTATTATGTTATGAAAGGACTTATGTCTTTTACCAGATTTCATGGAGATGGACCTCACTTTTATAAGTGGCAGAGAATGTTTCAGGATGGCGCTGGCGGAAATAAGGTCCACCTGATATTAAGAGTCAAGAAGCATCTTACTGATGAGGAACTGTACAACTTAATGGAGCAGGCAAGAAAATAAAAAAACGATAGCTATGCCACGAATTGATTTAATAAATGGTTATTATATTAGGTGATCATTTTCGTGGGGGAATGACGTATGAAAAGTTTTTGGAAAAAGAATGTTCTGATTTTTTTAATTGCAGTTATGAGCATTCAACTGATGGGGTGCGGACGCGGATATACATATAGAGATAAACTTTCAGTTGAGGTAAGAGCAAGAATTGCTGCGACGGCTTACCTGTTTAAAAACAAATTTGGCGCAGTATTATACAATGTTGATGCTTATGCACCTTTTGTTTTGATTGTCAAAGACTCGTTATACAACGAGGCTGAGTGTTCATATTTTTATAGAGGCAGTAAACATACTCTTTGGGTCAATAATGATGATGGCAAGATTTATACAGATGATCTTGTGGGATATGCCAATAAATCTCTGACAGACAGATTTGCCAGAAAGATAGGATTACCTGATGGAGAAAAGGTAGAACTGACTTACCTTCCGGACTATGAAATTCAGACATCTACCATAAATGATGGCAGTACTTATCCGGCTAATACTCACATTGATTTTTTTCCTTCTGAATATACTGAGCAGGATGTTGATGTGTATATATCTGAAGATAACTTAAAAGGTGAGATCAGGGATATAAAGATATATTCAAACAGAAGCTGCATGGATTATGACGAGATAGTGACAGCTGATAAGTATCATGAGCTTTTCTATGGTAAGGATGTAACGCTTTATTGCACTGATGGCTATGTTACCTATGAAACTGAGGCGGGAAGGACCATTATTGTAACTGTTTATAATGAGGACTCTTCTATTTACGCGGACAGGGTTAAGCTGGAATATTATGATGAGTATCGCTATTCCTATGGCTATTCTGTCAAGGATAAAAAATATGTGGTCAGCCAGAAGGCATTTACGGATTATAGCAGTAAAGACTTTGATGTGAACCTGAATGGCAGAGGAACTGATACGGTCTTAAAAGTAAGGACCAGAAGAGATATTAAGGCTGATTTATATGTTTATGGATTAAATCGTTTAAAAGTAAAATGTACCTATGATCATATATATGCACAAAATAGTTATCCAAGAGAGCAGAGCTACAAGGTATTTAATTGTAAGAATGGCTGGAAGAAGCTTGTTGATTCAAGAATAAGAGAAATTAAACATAGAAAAAGCGGCATTGTTCCGAGCTGTGATCAGAGAGTTTTTTCTTTTAACAAGGATTCGGATTACGTGTTAGATATTTAGATTTATTTTTGATACATATTTCAGTTTTAATTTCATTTAAAATTTAGTTGCGTTATACGTATTAAGGCTGTAAAATATTTAGCGGACAATGTCTGTTAGATTTTTAACGCTTGTTTATATTGGATTTAGGAAGTGGTTTGATGTTGATTCTTAAGGCTTTTGGCTTAATAGTTTTTTTAATGTGCGTGTTATACATGCTTATGATTATGCCAAGAGTGGTGAATAAACCATCAAGTGAACCCTTCACCCGGGTCTTATATGCTCATAGGGGACTACACGATAACAGGAGCAATGCACCGGAGAATTCAATGGCAGCCTTCAGAAAGGCTGTGGAGGCCGGATATGGCATAGAATGTGATGTCCAGCTTACCAGGGATGGGGTTCCAGTTATTTTCCACGATTTTACATTGGCAAGGATTGCCAGATATCCTGATGGATGTGTTCCTGCAGATGCAGTTCCTAATCCGGATGGGAGCCTTGGAGTAAAAGGCAAGGTAGTCGATTACACATACGAGGAGCTATTACAATTTCATTTACTTGATTCTGATGAGAAAATCCCAAAATTTGAGGAGTTTCTTCAGATGGTAAATGGTACAATTCCAATTATTGTTGAACTTAAGATCGAGCTTAAGGATTTAGCAGTATGTCGTAAGGTGGACGAACTTCTTGAAGATTATAAGGGGATTTACTGTATAGAGTCCTTTAACCCTCTTGGAGTTATGTGGTATAGGAAGAACAGACCACAGGTGTTCAGAGGACAGCTTTCTGATGCGTTCCACAAGGACAAGCCGGAAGAATTTCAGGGGCCTTTGTACTTTATACTTACTAATTTATTATTTAACTTTCTTACAAGGCCGGACTTTATTGCTTTTAATCACAAATATGCAAACTGTCTTGCCAGAAGGATTTGCAGACGCGTTTATGGCAACGTTGCCGCAGCCTGGACCATCAAGAGTGAAGAAGAATTGGCGAAGGCAAGAAAGCATTTTGACATATTCATCTTCGACAGCTTTGTCCCACAGAGTGGCCCCAAAGCGTAAACGTATTTAATTTTTATATGGTAATTGCATACATTTCTACTAATGTCAGCTTCTGTGATGATACATATGGCCAGAAGTGAGGTGATTTGTAGTGATTCATGATGGCGAGAAAATATGCAAAAAATCCGATTTGATGCGCAGCATCATCGGAGGATTTTTTACATATTTCGAGTCGAATGAAAACACAAAACACCGGATTACCGGGCATATGTATCGTTACGGAAGCGTACGGTAGAGTGTAGTGATTATAATAAATGCACAATATTGAAAGGTGCCGCTTTATTAGAGGAGCGGCAGGAAAGGTAGAAAACATGGCGAACAAGTGGGTTTATATGTTCAGTGAAGGTAACATGACAATGCGTAACCTTCTCGGTGGTAAGGGCGCTAACCTTGCAGAGATGACAAGCATTGGCCTTCCAGTACCACAGGGCTTCACAATCACAACTGAGGCCTGCACACAGTATTACGAGGATGGTCGTAAGATCAATGACGAGATCATGGCTCAGGCTATGGAAGGCGTCAAGAAAATGGAGGAGATTAACGGCAAGAAGTTTGGCGATCTTCAGAACCCTCTTCTTGTATCTGTTCGTTCAGGTGCTCGTGCATCAATGCCTGGTATGATGGACACAATCCTCAACCTCGGTCTTAATGATGACGTAGTTGCAGCAATGATCAAGGGCAATCCTGATCCTGCATTCGAGCGTTTCGTATATGATTCATATCGTCGTTTCATCCAGATGTTCTCAGATGTTGTTATGGAAGTTGGTAAGAAGTACTTCGAGCAGCTTATCGATGCAATGAAAGAGAAGAAGGGTGTTAAGTTCGACGTTGACCTTACAGCAGCTGACCTCAAGGAGCTTGCAGAGCAGTTCAAGGCTGAGTACAAGAATCAGCTTGGCAAGGACTTCCCTTCAGATCCTGTAGAGCAGCTCAAGCTTGCTATTGAGGCTGTATTCCGTTCATGGGATAACCCTCGTGCTAACGTATATCGTCGTGATAACGATATCCCATATTCATGGGGAACAGCTGTTAACGTAATGCCTATGGTATTCGGTAACCTTAATAATGAGTCTGGTACAGGTGTTGCATTCACACGTGACCCTGCAACAGGTGAGAATAAGCTTATGGGTGAGTTCCTTATCAATGCTCAGGGTGAGGACGTAGTTGCTGGTGTTCGTACACCTATGCCAATCGCTCAGATGGAGAAGGAATTCCCAGAAGCATATGCTGAGTTCATCAAGGTTTGTGAGACTCTTGAGAACCACTATCATGATATGCAGGATATGGAGTTCACTGTTGAGAACAAGAAGCTCTATATGCTTCAGTGCCGTAATGGTAAGAGAACAGCTCCTGCTGCTCTTAAGATTGCTTGCGACCTCGTTGATGAGGGACACAAGACTCCAGAAGAAGCTGTAGCAATGATCGATCCTAGAAACCTTGATACACTTCTTCACCCTCAGTTTGATGCTGCTGCTCTTAAGGCTGCAACACCTATCGGAAAGGGTCTTGGTGCATCACCTGGAGCTGCTTGCGGTAAGGTTGTATTCACAGCTGACGATGCAGTTGAATGGGCTGCAAGAGGAGAGAAGGTAGTTCTTGTAAGACTTGAGACATCTCCAGAAGATATCACAGGTATGAAGGCTGCTCAGGGTATCCTTACAGTTCGTGGTGGTATGACATCACACGCTGCCGTAGTTGCTCGTGGTATGGGTGAGTGCTGCGTATCAGGTTGTGGCGACATCAACATGGACGAAGAGAACAAGAAGTTCACACTTGCTGGAAAAGAGTTCCACGAGGGAGACTTCATTTCAATTGATGGTACAACAGGTAACATCTATGATGGTCAGATCGCAACAGTTGACGCTCAGATCGCTGGTGAGTTCGGACGTATCATGGCTTGGGCTGATGAGTTCAGAAAACTTAAGGTTCGTACAAATGCTGATACACCTGCTGATGCTAAGAAGGCTAGAGAGCTTGGCGCTGAGGGTATTGGTCTTTGCCGTACAGAGCACATGTTCTTCGAGGAAGACAGAATTGCTGCATTCCGTGAGATGATCTGCTCAGATACAGTAGAAGAGAGAGAAGCTGCTCTTGAGAAGATCCTTCCTTATCAGCAGAACGACTTCAAGGCTCTTTATGAGGCTCTTGAGGGATGCCCTGTTACTATCAGATTCCTTGATCCACCTCTTCACGAGTTCGTTCCTACAACAGAGGACGAGATCAAGAAGCTTGCTGAAGCAAAGAATAAGAGCGTAGACGAGATCAAGGCTATCATCAACTCACTTCATGAGTTTAACCCTATGATGGGTCACAGAGGATGCCGTCTTGCAGTTACATATCCTGAAATTGCCAAGATGCAGACTAAGGCTGTTATCCGTGCAGCTCTTGAAGTTCAGAAGGCACATGCTGACTGGAACGTTAAGCCTGAAATCATGATTCCTCTTGTATGTGAGGTTAAAGAGCTTAAGTATGTTAAGAAGGTAGTAGTTGAGACAGCTGATGCTGAAATCGCTGCTGCAGGCGCTAAGCTTGAGTATGAAGTTGGTACAATGATCGAGATCCCAAGAGCTGCTCTTACAGCTGATGAGATCGCTAAGGAAGCTGATTTCTTCTGCTTCGGTACAAACGACCTTACACAGATGACATTTGGATTCTCTCGTGATGATGCTGGTAAGTTCCTCAATGCTTACTATGATACAAAGATCTTCGAGAACGATCCATTTGCTAAGCTTGACCAGACAGGTGTTGGTAAGCTTATGGAAATGTCACTTAAGCTTGGTAAGCCAGTTAACCCATCACTTCACGTTGGTATCTGCGGAGAGCACGGTGGAGATCCTTCATCAGTTGAGTTCTGCCACAAGATCGGACTTGACTATGTATCATGCTCACCATTCCGTGTTCCTGTTGCAAGACTTGCTGCTGCTCAGGCTGCTATTGCTGAGAAGGCTGCTAAGAAGTGCGACAAGTGCGAGGATGCTACAAAGTCTTTCGTAGATGATGAGACCAAGCAGAAGCTTCACGATGCAGCTGAGAAGGCTCAGGAAGTAGCTAAGGTTCTTGCAGAGCAGTCAGCAGACGTTGCTAAGGCTGGTCTTGAGGGACTTAAGGCTGGTGTTGATGCAGCTGTTAAGGCTTACAAAGAGACAAGAAATAAATAATTAAGATTACAAAAACTATTTTGTAATTAGAAATAAAAGAAGGACTATTCAACCATGAGTAGTTCTTCTTTTTTGTTATTTTTTGTACATTATAATTTTATATTGTGTTTATATATTTCTGTTTTTAACGTGATATAGTTTAATGGTAGATGTCGGTATACCGATAATTTCTGTATGAAAGGAAAATATTATGGATAAGAAGCACGGCTCTTTAATGCTACCAATTGTCGGATCTATCATTCTTGCAGTAGTAATCACTGCTGTAGCGATTGCGGGCTTTAATATTTATAGCTCTATCAATACTAATAAGTCTCAGACTGAGGCTTACAAGGCAAGACTGCTTGAAGATGTTCAGGCTGAGCTCAAGAATGAGACTCAGGAAGCTATGAGTATCTGCCAGGTTATGTATGACAGATATCTTGCCGGTGAAATGACCATGGAAGAAGCTCAGAAAGAAGCTGCTGATATTATCCGAGAACTTAAATACAATGATGGCGCAGGATATTTCTGGGTTGACACATCCAAGGGAATTAACGTTGTTCTTCTTGGGCGTGATACAGAAGGCCAATCCAGATGGGACAGTGTGGATCCAAATGGAACATATTTCATACAGGAAATGATCAAGAACGGTCTGCAGGAAGGTGGCGGATATACAAACCTTATGTTTGCAAAGCCTAATGAAACAGAACCACTTCCTAAAATAAACTATACAGCATATTTTGAGCCGTTTGACTGGGTAATGGGTACCGGAGTATGGGTTGACCATTTAGATTCACTTGCTGCAGAATACATTGGCCATGCAACTATGGATATGTACAGAAATATTAACAGTTCGATCATAACAATGCTTGTATTGCTTGTTATTGGTATTTCTATTGCTGTATATATGGGAAAGAGAATCACCAAGCCCCTTATCCTTGCAACTGAGCAGATGGTTCGTATGTCTAATAATGACTTTACAGACAACGAAGAAATGGAGAAGGTCAGAAGTCTTCCAGCTAAAGAAAATAATGAGATCGGACAGATTGCAGAAGCACTTGATCTTATGCATAAGAATATCAGAGACCTCATGATGAAAATCTCTGATACTACAGCATATGTTGCCTCTGCTTCTGAAGAGCTTTCAGCCAGTGCTTCACAGTCAGCACAGGCAAGTGAGATGGTTGCTAACTCTTGTACGAATGTTGCAAATTCCTGCTCTGGACAGATTACCGCAGTTTCAGGGGCAAGTAATGAGACTAAGGCGTTTGTTAACAATATGCAGGAGTTCCAGGATGCTATAAGCAGAACAACTGAAATGATAGATACTACAAATGACGCTGCTACTAAAGGCGCTGCTGATATGACAAATGCAACTAATATGATGAAAACAATTAAGGATTCTGTTGAAAATACAGCTTCTGTTGTTGAAACACTTGGTGAGCAGCTCAAGAATATCGACAGCTTTGTTGATACTATTGCAGAGATTGCCAGCCAGACAAACCTTCTTTCACTTAATGCAAGTATTGAGGCCGCAAGAGCCGGAGAAATGGGTAAAGGCTTTGCAGTTGTTGCTAGTGAGATCAGCAAACTGGCAGATCAGTCCAATGAGGCTGCTTCCAAGATAACAGAGCTCATAGCTGAGATCATGCAGAATTCTAATGAAGCGGTAGAAGCTATGCGCTCCGGTGCTCAGAGCGTTGTGGAAGGAACTGAGACTGTTAACGAAGCCGGAAATACTTTCGGCAATATTGTTGAGATGGTTTATTCTATATCAGAGCAGTCTGCAAGAATGAGCGAGATTGTCGGACAGCTTTCAGAAGGAACAGAGACAATTGCTGAGAATATCCAGAAGATTGAAAATATGAGTGCTGATGTTGCGGATGAAACGCAGAATGTTTCAGCTGCTTCAGAACAGCAGACAGCATCGACGCATGAAGTTGCAGAAGCTTCAGACAGACTTGCTGAAAATGCTCAGGAACTTCAGAACTTTGTTGCCAAATTTGATCTGTAACCGTCTGACCGATATAAAATCTGCTATTACAAGGGCTGCGATCAATAATCGATTGCAGCCTTTCATATTTTACTAAACGATAATTGCTCCAAATAGTTGCAAGTAACTCTATATGGATAAATGATGCGTTGAGAAGTTAACTATAAAGTGATAAAATTAATATGTATTAGTGTATTCATCTAGAGGGCCATATATGGACGTCCAGGAAATTGATCTTATCAACGAACTGAACATATATACGGGACTGGATTCGTTCAGCGAAGATGCTCTGGAAAAAGAGCTGGCGCAGTGCAAGGGACTGGGAGCAAATGTCGAGAAGCTCCGCAGTCTTGGTTTTAATGCACTTCAGCTGGCAGAAATAAGAAAGGGCCTTGAAAGCGATAAGGTTGATGTAAATAAATATCTTGATTCTAGTCTGTCCTGGACGGATATGGAAGAAATGCGCCTTGAAATGGTGCAGGGAATTGATATGTCTGAATATCGGGCTAAGGGCTTTGATAATCAGCAGCTGTATCAGATAAGAACCGGAATTTCTGATGGAGTAGATGTATCTGTTTATGCCAAAAAAATCTATCTTGCAGATCAGATGAGAGAGCTGAGAAGAGGGCTATCTCCAAAAGATGGTGTCCCTATTATATTTTTTCAGGATCCGGCATTTGATTCCTTACAAATGAGAGAAATAAGAAGAGGCCTTCAGGTTGGAATAGATATCTCAACCTATGCAATGCTTGACATACCTCATATGAAGATGAGGGCAGCCAGGTTAAGCGCTCAGGACGGCCTTGTATTTACTGAGGCGGAAATTCGCAAATATACAGCAAGTATATTGGAACAGATGCATCAGGCACATCTTGATAATGTAAATATAAGCAGTTATGTTAAACGCTTATTCGATGCTGAACAACTTGAACAAATCAGACTTGCACTCAAAAAAGAACTTCCTATAGATAACTATATGACTGCGGACATGCGCGGCGAAGCTATCAAAGAGATTAGGCTCGGCCTTGAAGAAGGTGTTGATGTTGGTAAATATGCTGATGTAGCCTATAACTGGAAGCAGATGCATGAAATGCGACTGGGACTGGAACATCAGATAGATATTACACCATATTGCAAGCCTTTGTATCAGGCTGACCAGATGAGAGAATTGAGGCTGGGAATAGAAGCCGGACTTGATATCAGCAAGTTCTCTTCTATGATGTATACAGCCAAGGATATGTATCGCATCAGGAATAAGATTCTGTCAGGAGAACTTCAGAGCACTGTATCAGAGGATTCTCTTGAAGGATCTGTCTTTGATCGTACAGGCGGAGTATCTGATCAGACCATTCTTTTATCTTCCATGCTTGAAAACAGAGACCAGTATCTTTATGTTTCAGAAGATAAGATGAAATGCTGGATTATGTTGCCTGTTAGAAGAGATGGCATTAGTTACACTGAAGACGCGATAATGACCTTTCTCTTTAAAACGAAGATCAGGAGCGGAATAGACAGAAAGAGTATCAAACAGGCTCTTTTGAATCCGGAGCCTAAAGAAAAATATCTCATTGCACAGGGAAAAGAAGTGATAGATGGCGCGGATGGACATTTTGAATACTTTTTTGACTATGAAAAGAACAACGAGGTCAAGGTTTTAGAAGACGGAAGTATAGATTTTTCTGATGTTGAAAATATTCAGCAGGTTAAAGTAGGAGATAAGCTTGCTGTGTACCATAAAGCGACCAAGGGAATAGATGGATTTACTGTTTACGGTGAACTGGTCAAAGCCAAAAACGGTAAGGAAGTACCTATTCTTAAGGGTGATGGCTTTATGATAATGAGTGACAGAGTTACTTATGTTGCCAAGTATGCAGGAGCTATAAGTGTTGAAGAAGGTAATGTCTATATTAAGAAAGTAATGATATTACCTGAGGTCAAGATTACTGATAAAAAAATAGATTATGACGGAGTAGTGTTTATAAGGGGCGATGTGCATGCCGGAAGTGAGATACGCGCTACGGGCGATATTATTATTGGCGGGCATATGGAAAGCTCTGATATAGAGAGTAAGTGCAATGTCATAATCGCAGGCGGTGCTACCTGTCCAACAAAAGGAAGTATTGTGGCAGGAGGCGATGTTACAGCCAAATTTTTTGATGGAGTAACTATAAAAGGACATAACATTTCGTCCAATTACTTTATAAACTGCAAGATTGAAGCCAAGGGCATGCTCAAAACCTTTGGCAGACAAGGAGTTATTTATGGCGGAACCGCATATAGTCTCGAGGGAATAGAATCTGCAGAAATTGGTAATGTTTCAGGAGCCAGAACGACGATCACACTTGGTGCCAATACTGCGCTTTTGGCAGAATATAGTAACCTTCAGAAACAGATCAGCAGAGAGGCGGAGAACCTTAAGAATCTGATCATACAGAGGGATAAATTACAGGAACTTGGTTCGGGTAATCCGCAGATCATGCAGCTAAAGATAAAGGTAAATGCAGCAATAGCAATCAAACAGCAGGCAATCAAGAATCTGGCTGACAAGAAACAGAAACTTGACAGTGATGTAGAAAAAGGCGAAAAAGCTATGGCTGTAGTCACAGAACAAATTTTTGCCGGCACTATAATCATTATAGAAGGTCTTGCACTCAAAATAACTGAAGATAGAAAAACTATTGATAAAATTGTTTTTAGAACTGACCCCAAAAAAGAAAAAATACTAGTATTTTAAAATGCAAAAGATGTTTTTTTAAACTTTGAAAAGGTCCATAAAGCCCCATTTTATCTTGCACAAATGGACATACTTTTCTATAATAAAAGATGATTGCTTCTGGGGGTTTTAAATATGAATATTAAGGAATTACTTAAAGAAATTCTTCTTAAGGACAAAGCTTTTATCCATTTGCCGTTTGGAAATGGCAAATATGATATCTATGAGTCTGTTGTGGTCATGTGGATCATAATGGCTATACTTTTTATTGCTCTTTTAATTCTTACCCGCGATTTTAAAGTACATAATATTTCCAAAAGACAGGCTGCTATTGAATCTTTCGTGGTCTGGATAAGGAAAATAATTGGAGGATCTCTAGGTGAAAAGGGAGAGAGATACACTGACTACATAGTCAGCATACTGATTTTCCTTGGAGCGGCTAATATGATTGGCCTTCTGGGATTTATTCCTCCTACAATGGATATAAATGTTACAGCAGCTCTTGCTTTTATGAGTATTGTGCTTGTGGAGGTCGCTGCTATAAGAGAGAAGGGTGCTAAGGGATGGCTTAAGGGCTTTGCCAAGCCAATGGCCATAGTACTTCCTATGAATATTATGGAACTTGCAATCAGACCTTTGTCTCTGTGTATGCGACTTTTTGGTAATATCATTGGAGCCACAGTTATCATGGAGCTTATCAAGATGGTACTTCCGGCAGTTCTTCCGGTTCCATTCTGTCTTTATTTTGATATTTTCGACGGTCTTATTCAGGCATATGTATTTGTATTTTTAACATCACTCTATATTAACGAAGCAGTTGAGTGATGGTACCAAAATATAGCAATTCAAAAATGGAGGTAAAAAAATGGATTTAACAGCATTAGGAGCAGCAATTGCGGTATTTACAGGTATTGGAGCAGGCATTGGTATCGGCGTTGCAACTGCAAAGGCAACAGACGCAGTAGCAAGACAGCCGGAAGCTAATGGTAAGATCATGACACTTCTTATTACAGGTTGTGCGCTTGCAGAGGCTACAGCTATTTATGGCTTTATTGTAGCTATCATGATCTTGTTTACTTAATCAGGCACGAGAGGGAAGGGTACTAAGGTGTTAGAATTTAGTTTTGTAAACATTATATGTGTAATAGTAAATATACTTATTCTCTACCTGATTTTCAAAAAGTTCCTTTTTGGAAGAGTAGACAAGGTTCTTATGCAGCGCAAAGAAGAAATTGATGAGGCCACTAAGGCTGCTGATCTTGCAACTAAAAAGGCTCTTGAGACAAAAAAAGAGTACGAGGACAAGATTGCTCTTGCTGATGAGGAAAAGGAACAGATCCTGGCCGATATCAAAAAGCAGGGCTATGACGAGTATGATCGTATTGTCAATGATGCCAAGAAAAAAGGTGAGAAGATCATTACAGAAGCCAAGCATAATGCTGAGGTAGAGAATGAGAGAGCTAAGGAAGTGTATGCTGCCCAGCTCACAGATATGGTTATTGATGCTGCTTCCAAGATTGCAGCGACCAAACATAGTACACAAGACGATAGAGAACTGTATGATAAATTTATAAATGAGGCTTGAGCAGATAATGAGTGAAAAACTATTAGCGAAACTGCGATATGCCAGCACTTCTCCGACTCCGGAGCAGGTCAATGGAATAAAGGCCATGCTCTGCAAGAAGTTTAATGTCGATGACATTGAGCTTGAGCTCAGTGAAGATAAGTCTATTGGTGGTGGCTTTATTGTATCCTGCAAAAACTATGAGTATGACTGGTCTGATGCAGGAAGAGCCAAACAGCTGCGCGCAGAAATTAATAATCTCAGACGTGAACATGGTGGCAATGATGCCGGCAAGATTATTTCTATGCTCAGTGATAAGGTTGAGAATTTTGACCTTGCAGTTGAGGATAAGGAAGTCGGCAGTGTTGTCTGGGTAGGTGATGGAATTGCCAATATTGATGGCATTGAGCACGCCTTCTACGGAGAGATAATAGAATTTGAAGATGGAACCAAGGGAATGGCCCAGGATATCAGAGATGATCATATTGGGTGTATTCTGTTTGGTAATGATGCAGGAATCAGACAGGGAACCAGAGCTGTCAGAACATATAAAGAGGCTGGTATTCCTGTTGGAGAAGCTTTCATAGGAAGAGTAATTGATGCTCTTGGTGCTCCTATTGACGGGCAGGGTGATATTAAGGAATCCGGATACAGACCTGTAGAAGGACCAGCTCCAGGTATTATTGACAGACAGTCTGTTAATGAACCTATGGAAACAGGCATTTTGTCAATTGATACAATGTTCCCCATTGGACGAGGCCAGAGAGAGCTTATCATTGGCGACAGACAGACAGGTAAAACATCTATAGCTCTTGATACTATCATCAATCAAAAGGGCAAGGATGTAATCTGCATTTATGTAGCTGTAGGCCAGAAGGCATCAACCGTAGCCAAGATCATTCAGATACTTAAAAAGACAGGAGCTATGGATTATACAATTGTAGTTAGTTCTACAGCATCAGATTCAGCTCCGCTGCAGTACATAGCCCCGTATTCAGGAACTGCGATGGCCGAGTACTTCATGCATGAGGGCAAGGACGTGCTTATAGTTTACGACGATCTTTCCAAGCATGCTGTAGCTTACAGAGCGCTTTCTCTTTTGCTTGAGAGATCACCAGGTCGTGAGGCATATCCAGGAGATGTATTCTACCTTCATTCAAGACTGCTTGAGAGATCAAGTAAACTCTCTTCAGAGCTTGGAGGAGGCTCGATAACAGCGCTTCCTATCATAGAAACTCTTGCCGGAGATGTATCAGCATATATTCCTACAAATGTAATATCAATTACTGACGGACAGATATTCCTTGAAAGTGACCTTTTCTTTGAAGGAATGAGACCTGCCGTTAATGTTGGTCTGTCTGTTTCCCGTGTAGGTAGTGCTGCTCAGACTAAAGCTATGAAGAAGGCTGCAGGCAGTATAAGGGTTGATCTTGCCCAGTACAGAGAAATGGCTGTGTTTACCCAGTTCAGTTCTGATCTTGATGAGACAACCAAGAATCAGTTGGCTCACGGTAATGTATTGATGGAACTTCTCAAGCAGCCACTGGAGCATCCGCTCGCTATGCATGAGCAGGTTATTATCCTTGTTGCAGTTGGTGCTAAGCGACTTGATATGATACCTGTCAAAAAGGTCAGAGATTACAAGGAAAGACTTCTCGAGTATTTTAATACCGAGCAGGGAGAAATCTGTCAGGAACTTGAGAAAAGCGGAGATTTATCTGACCAGCTTAAGCATAAGATCATTGAAGCTGTCGATGCTTTTAACGATATCGAGAATAAAAAACTTAAAGAAGAAGTAGAAGAAATTCAGAAAAATAATCACTGAACTATTGGTGTGAATGACAAGTCATAAACAGAGGTTTGATAATTGGCAAATATCAAGGAAATTCGTGACCGCATAAATAGCGTTAACGATACTAGAAAAATTACAAATGCCATGTATCTTATTTCTTCCACTAAGCTTCGAAAAGCCAAGAAAATGCTGGATGAAACAGAACCATTTTTCTTTGCTACGCAGGCTATGATCTCGAGAGTTGTACGTCACCTTCCGGAGGGAGTTGAAAACGTATTTCTGGAATCAAGGTCTGAAATTCCGGAGCAGGACAGAAGAAGAGGCTATATCGTTTTTACAGATGATAAGGGCCTTGCCGGTGCCTATAATCATAATGTGATCAAGCTGGCAGAGGAACATATTCTTAATGATGGCGATAAATGGAAATTATTTGTTATCGGAGAAGTTGGACGATATCACTTTTTATCCAAGAACATGGATGTAGAAGAATCGTTTATGTTCACCTCCCAGAATCCTACTCTTCACAGAGCAAGGAAAATAGCAGCAGAGATTCTTGATTACTACACACGCAGAGAGATAGATGAGTTTTATTGCATCTATACAACTGTTCACAGTAATGTCTGTGAGACAAGATTTGAGAAGCTGTTACCACTTGATATCATTACGAACATTCGAAAAGAGAAGCCGGCTATAGGAACGATGCTTGAAGAATTTCTGATGGAACCGAGTCCTTCAGCTATCTTGGATAATATTGTTCCAAACTATGTAACGGGTTATATCTACGGAGCTTTGGTTGAAGCGTTTTGCTCGGTGCAGAGTTCCAGAATGATGGCGATGGATTCGGCCAACAAGAATGCTGCCAAGATGTTGGATGCTCTTCAGAGAACCTATAACAGACAGAGACAGGCTATGATCACTCAGGAAATTACTGAGGTGGCAAGTGGAGCTAAGGCACTCAAAAGAGCTAAATTGGCCAAGATGCAGAAAAGCAAAAAGAAGCAAATGCACGGCCAGGATGCAAAGATGATTGATGAAACAAGAAGATGAGGGAAAAGCCTTGAGTAATGGCAGAATTTTGCAGGTTATGGGACCTGTAGTAGATGTAAAATTTGATGATGGCGAGCTTCCATATATAACTGATGCTATGGAAGTGTATGTTGAGGACCAGAAACGAGTAATGGAGGTTTCTCAGCATATAGGAGAGGATGTTGTCAGATGCATTATGCTGTCTCCAAGTGAAGGACTTTGCAAGGATATGGTAGTTTATCCTACTGGAAGCCCTATAAGTGTTCCGGTTGGAGAACAGGTTCTCGGAAGACTGTTTAATGTTCTTGGTGATGCAATTGACAACAAAGGCGAGGTTAAATGCGAAGAAAAGTGGCAGATCCACAGAGAACCACCTAAGCTGGTTGACCAGAGCCCTGTAGTAGAAGTTTTGGAGACAGGAATTAAGGTTATAGACCTTTTGGCTCCATATGCCAAGGGTGGTAAGATAGGTCTTTTTGGAGGCGCCGGAGTTGGTAAAACAGTTCTTATCCAGGAGCTTATTCAGAATATTGCCACAGAGCATGGCGGTTATTCCATATTTACAGGTGTTGGAGAGCGTTCGAGAGAAGGTAATGATCTGTGGTCTGAAATGACTGAGTCAGGTGTTATCAACAAAACAGCCCTTGTATTTGGACAGATGAATGAGCCGCCGGGAGCACGTATGCGTGTTGCTGAGACGGGGCTTACTATGGCTGAGTATTTCAGAGATGTTAAGCATCAGGACGTTCTTTTGTTCATTGATAATATTTTTAGATTTGTACAGGCTGGTTCTGAGGTTTCATCGCTTCTTGGAAGAATGCCATCTGCTGTTGGATATCAGCCTACTCTTTCAACAGACCTTGGTGCACTTCAGGAGAGAATTGCTTCTACAAGACTTGGATCAGTAACATCCGTACAGGCTGTATATGTGCCAGCAGATGACCTTACAGATCCTGCACCTGCCACTACGTTTGCACATCTTGATGCGACGACAGTTTTGTCCAGAAAGATCGTTGAGCAGGGTATTTATCCGGCTGTAGATCCTCTTGAATCCTCAAGTAGAATTCTTGAAGAGGATGTAGTTGGCAAGGTTCACTATGAGACTGCAATGAAGGTTCAGGAAATATTGCAGAAGTACAAAGAGCTTCAGGACATCATTGCCATCCTCGGAATGGAAGAACTTAGTGATGAGGATAAGCTTACTGTTTACAGAGCTCGTAAGGTGCAGAGATTTTTGTCACAGCCTTTTCATGTAGCTGAGCAGTTTACAGGTATTCCTGGTAAGTTTGTACCGCTTGCTGAGACAATCAAGGGCTTTAAAGCTATTATTGATGGAGAGATGGATATTTATCCGGAAGCAGCTTTCTTTAATGTTGGTACAATAGATGAAGTTATTGAGAAGGCTAAGCAGATAGAGGCATAAATATGAGTGATGCAAGAGTAGCAACCTTTGGTCTTCAGGTTATTTCTGTTAATGGTATGTTCTATGATGACAGAGCTGAGGAGATCATTTTACCTCTGGATGATGGTGAACTGGCAATACTGGCCGGTCATGAGGAAATGATCCTTGCTCTTAATGACGGTGTCATCAAGATTAAAAAGCCTGGTGGAGAATGGATTTACGGTGTTGTGAGTCTGGGATCTGTTCAGGTTGCCAATAACAGATGTATTGTAATAGTTAACACTGTAGAGAGACCTGAGGATATAGATAAGAGAAGAGCCCAGGAAGCATATGAGTTTGCTATGGAGCATCTTCAGCAGAAGCAGTCGATCAAGGAGTTTAAGAAGTCTCAGGCAGGACTTGCCAGAGCTCTTACAAGGCTTAAAGCTGCTTCTAAATATTCTGACTGATATTAGGAGACATAATTTGTTTAGTAACAGAGCACATTTTTATATGATCATAATTGCGGTATGTAGTATTTTTCTTGCAGGATGTGGAAATAAGGCATCACAGGAGCTTACAGACTACAAGGCCAGCATGACGGAGTTTTACGATAAACTTTCAAGTCTGGATAATTCAATAAACAATATTGATACATCATCAGAGACTGCCAAGATTGAACTTTTGGGCTACCTCGATGAGATGAACGAAGCTTACAAGGTGATGGCTGCAACAGCTATTCCGGAAGAGTTTTCAGGAATTACAGATATTGCTGCTGAGGCTGCGGATTATATGCAGATGGCTAATGAAAGTTATCATCAGGCTTATGATGGCATTTTTGATGAAGATAGTGAGATGCTTGCATCTCAGTATTATGAAAGGGCAAATAGCAGAGTAAATGTTATGCTGCAGGTTCTCCACGGAGAAATACCGGAGGGAGACGGAGTTATAGTTACTACGCAGGAGGCAGGTCAGTTCTCTACTATAGGAGCAACCGCAGAATAAGTTCATGAAAGAAAACAGATTTTTATATGCTGCAAGGTTTATTGCCTGCCTTGCAGTCATAACTATACATACAAGGTTTCCGGGAAAATTTGGTCAGGTAATAGATGCCCTGGCCAGATTTGCGGTACCTTATTTTTTTGCAATTTCAGGTAGATTTCTTTTGGATGCTTCAGACAACTCTATAGCTTTCATCCGTATGAGAACAGGAAAAGCGCTTCTTAAACTGCTTAAGATTACTGGAATTGTATATATCATCCATCTTATTTTTTCTCTGGTAGTCAATATCTTTAATCAGATGTCGGTTTCAGAGTGGCTATCTTCCAAGTTTAATTTCGCAGAGCTTACTAATTTTGTTTTGTATAATTCCGGAAGATTTATATATGACGGCTCATATACCTTTGATCATTTATGGTATCTTTTTGCGCTTATATATGTATATGGCCTTATTTATATTTTTGCAGGAGTTTTGATAAAGTGGTACAAGGGACTTATCGGTATACTTCTTTTCTTTTTGTACCTGGGAATGCTGTTGCAGACCTATTACCCTATAAGACCATTTGGAATTAATATCTGTACCTGGTTTGTTATGAGAAACTGGTTATTTGTCGGTATTCCATTTGTGCTTATTGGAATTCTTTTTTCAGATCATATCAGAGAAATAAAAGCCACTCTTTCTCCCAAGGAGCTTGAAAAGTGGCAGGTGAGTACCGGATACAAGGCCATTGCAGGACTTGTTTTTGGCATAGTCCTCACGATAGCAGAAATTGGAATATATGGAAATAAAGAGGTTCACTTTGGATCTCTTTTTATAGTGATCAGTATTTTGTTTATGTCAGAATGCAGGATTCCATCCGGAAACTATATATGGAGAATAGGTAAAAGAGCTTCTTCAAACATTTATTATTATCATGTGCTGATCATAGCCGTGATAGATATTATGGCTCAGAAAGGTATTATCCCTTCGCTTTCAATGGGGATTAAGCCTTTGATGATAATGGCTATTTGTGTGATTTTATTCTATTTTGTTCCGGTGTATTTTGAAAAATGGTTAAAAATGTCATCTAGTAGATGATGTAATTTAAGGTTATATTTGATAGTAAAAAATAAAGGATACGACAATGACTAAGGAAGAATTTTGGGGTCTGAGTAATAATAGAATACTGTTTCTGGACGGTGCTACGGGAACGAATCTTATGAAGGCCGGAATGCCGGCAGGAGTGTGCCCTGAGAACTGGATACTTGAGCATCAGGATGTAATGATAAATCTACAGAGCAATTACGCCAAGGCAGGTGCGGACATTATATATGCCCCGACTTTTACAGGAAATAGGATAAAACTTGCGGATTATGGTCTGGGAGACCGGATAGAAGAAATCAATTCAAGTCTTGTTAAACTCACCAAAAAAGCGGCACCGGGAGTTCTTGTCGCCGGAGATATTACCATGACCGGAAGACAGCTAAGGCCCATAGGTGATCTTGACTTTGAGGAGCTTGTAGATGTTTACAAACAGCAGATCAAAATACTGGAAGCAGCAGGCTGCGATATTCTTGTTGTAGAGACTATGATGAGTCTTCAGGAGTGTAGAGCAGCACTCATAGCGGCCAAGGAAGTTACTGACCTAGCGGTTATGGTTACCCTTACCTTTGAAGCTGATGGCAGAACTCTTTATGGTTCAGATGCTGCATCAAGTGCAATCACATTAGAAGCACTTGGAGCATGTGCTATAGGCGCGAACTGTTCCACCGGACCAGATAAGATGGCGGCTATTATCAGCGATATGGCTGCTGTGACAAGTATTCCGATCATTGCCAAGCCTAATGCAGGACTTCCATCTGTTGATGAGAATGGTAATACAGAGTATGACATGGACTGTGATACCTTTGTTAAAGAGATGGAACTTTTAGTAAGTGCAGGTGCTTCTATTATAGGCGGCTGCTGCGGAACTACCCCTGATTATATAAAGGGGCTTAAAGACAGATATGGTAATGTTAAACCAAACGATATAAGAGATGGAGAGGGAAATCCTGTTCCCAGAAAGATCTGTGGCAGAAGATATCTGGCTTCTGAGAGAATGAGTCTTTCTTTTGGTCTTGATGAGAATTTTATGATAGTCGGCGAGAGAATCAATCCTACCGGCAAAAAGAAGCTTCAGGAACAGCTACGAGAAGGCAATCTTGATATGGTCTGCGATTTTGCTGCCAATCAGGAAAAAGAGGGAGCTTCTATTCTTGATATAAACGTTGGAATGAGCGGAATTGATGAAAAAGAAATGATGCTCAAAGTTATGGAAGAAGTTATGTCCATTACTGACCTTCCTCTCTGCATTGATACAAGTAGTGCAGAAGTTATGGAAGCAGCCCTTCGTCTTTATCCCGGACGAGCTCTTATGAATTCAATTTCTCTTGAAAAGGGTAAGGCTGAAAAGTTCCTTCCTCTTGCCAAAAAGTATGGGGCTATGTTTATTCTTTTGCCACTTGCTGAAGCTCTTCCCAAGGATAGTCAGGAGAAGATAGATAATATCAATACAATTTATGAAATGGCCACAAAACTTGGGATGAATAAAGAGGATATCGTTGTTGACGGACTTGTTGCAACGGTAGGTGCTGATCCAAACGCGGCGATCAATACGCTTGATACTATAGGATATTGCCATGAGAACAGCTATGCAACTATCTGTGGCCTTTCCAATATTTCTTTTGGCCTTCCTCAGAGAAGCAACGTTAACACAGCCTTCCTTACGATGGCGATTGCAAGAGGCCTTACAATGGCAATTGCTAATCCTTCGCAGGAAATGTTGGTAAATGCAGCATTTGCTTCAGACCTTCTTCGTAAAAAAGAAGGCGCTGACGTAAGATATATAACAAGAATGGAGCGCTATGCAGATCAAAACTCTGCAAATAGTGCAGCTCAGAACGTATCTTCATCCAAAGCTGTTTTGGAAAACGATAATATTCTTGATATAATTAAGAAAGATGTACTTACAGGAAACAAGAGAGGAATTGTTAAGGATACTGAGAAAGCTGTTAAAGAAGGCAATTCCCCAAGACAAATTCTTGATGAGATACTTATGCCTGCAATTAATGAAGTAGGAGATCTCTTTGATAAGGGCAAATACTTCCTTCCTCAGCTGATAGCAGGTGCTGAGGCGATGAAGCTTTCAATCGGATATCTGGAGCCTCTTTTAAAAGAGGGGGCTGACTCAGGAGAAAAGCTTCCTTCTATCGTGATAGCTACTGTTCATGGAGATATCCATGATATTGGCAAGAACCTTGTGGCTCTTATGCTCAAGAACTACGGCTTTAATGTTATCGATCTTGGCAAGGATGTGCCAAGAGAGGAAATCATTAAGGCTGCCAGGAAATATGATGCTAAGATAATTGCGCTTTCTGCGCTTATGACTACTACGATGAAGGAAATGAAAAATGTAGTAGACCTGGCCCACGCGGAAAACCTTGATGCCAAGATCATAATCGGCGGCGCAGTAGTGACTCAGGATTATGCAGATGAGATTGGAGCGGATGGCTACTCTTCTGATGCAGCCGATGCGGTAAGAGTTGTCAAGAATATACTCGGAATAGAATAAAACTGGAGGAACCTATGACAGGGGCAGAAGTAATCGTAAGATGTTTGGAAAAAGAGAACACCAAGGTTATTTTTGGTTATTCAGGTGTTGCTATAGATCCTTTTTGGAATAAGATTCTTGATTCTAAGATAAAAAGAGTGCTTGTTCGTACTGAGCAAAATGCAGCTCATCTTGCAAGCGGCTATGCCAGAATAAGTGGGGGAGTCGGAGTGTGTGCTGTTACTTCCGGCCCGGGTGCTACGAACCTTATCACGGGTATAGCAACTGCATATGCTGACAGTATTCCGCTTGTTGCTATTACAGGGCAGGTCAACAGCGATATGATAGGAAGTGACGTTTTCCAGGAAGCTGATATTACAGGTGCTGTAGAGTCTTTTGTTAAGTATAGTTATCTGGTAAGAGATGTTAATGACCTTCCGAAAATAATCAAAGAAGCTTTTTACATTGCCAGTACAGGCAGGAGAGGTCCTGTTCTTATTGATATTCCATTTGATATTCAAAATGCAGAATACAAAGACAAGTTTGCTTATCCGGAATCTATTTCTATGCGAAGCTACAAGCCTACCGTAAAGGGAAATATGGCTCAGATCAAAAAAGTCATCAAAGAGGTTGAAAAGGCCAAAAGACCTATTATCTGCGTGGGAGGTGGAGTGCACCTAAGTCAGGCAACAATGGAAATCAGGAAGTTTGCTGAACTTAACAGCGTTCCTGTTGTATCTACCATGATGGGAATAGGCGTTATGCCATCTGACCATCCGCTTTTCTTTGGTATGGTTGGAAACAATGGTCAGCCCTTTGCTAACAGGGCTATGAATGAGTCGGATCTCCTTCTAATGGTAGGAGCAAGAGTTGCAGACAGAGCGGTCAACAGACCGGACCTTATTACAGAGAATAAGGTAATGGTTCATATTGACGTTGACCCGGCTGAAATTGGTAAAAACGTCGGACCTACTATTCCTCTTGTTGGTGATATCAAGAATATTTTCCAGGATTTTCTTGAACAGGATGAGCATGCTGATGATCACAGCGACTGGCTTGCTACTCTTAATAAATATAAAAACGAGATGGCCTCTGAGAGGGTGCCACGCGATGATGATTATGTGGAACCTAAGGATTTTATGACAAAACTCTCAGCAGCAGTAAATGATGATGCAATCTATGTTGCAGATGTAGGGCAGAACCAGATGTGGTCCTGTGCTTACTACAAGGTTAGAAACGGCAGATTTCTGACATCAGGCGGAATGGGAACAATGGGATACTCTATTCCGGCAGCAATGGGAGCTAAGCTTGCTGCTCCTGACAAGCAAGTGCTTGCTGTCATCGGAGACGGAGCTTTCCAGATGTCTATGATGGAGCTTGCCACCATGAGACAGTATGGCATTAACATCAAGATAATCGTTATGAAGAACGGCTTTCTTGGTATGGTGAGAGAACATCAGCATTATGCTTATGATGATAACTACAGCATGGTAGAGCTTAAGGGAGATCCGGATCTTTCCCTCATAGCAGCTGCCTACGATATGGAATACATGAAAGTTACAGGGGATGATAGTATAGAGAACAAGCTCAAAGAATTCTTCTCAGATGACAATGCAGCTATTATGGAAGTTCGCGTAGACCCTATGGAACTTGTTAAATATTAAATGTCAGAAAACTGGAGTGGCGAAAAATGCGTAGAATTTATTCAGTACTGGTTGAGAACAGAGCCGGTGTTCTTTCTAAAGTGGCAGGTCTTTTTTCCAGGAGAAACTTTAATATAGATTCTCTGGTTGTAGGTGAAACTGCTGATAAGGGAATATCTGCCATGACCATTGTTTCCAGCGGTGATGAGCGTACAATAGAGCAGATTGAGAAACAGCTCAATAAGAAAATTGATGTCATCAAGGTTAAGACCTTTAAGGAGAGCATGTCCATAAACAGAGAACTGATGCTCATTAAGGTTAAATATAACAGAGACAACAGACGTGATATCATGGAGAACTGTGAGATCATGAATGCTCAGATTGTTGATATGTCCAAGAATCTTATGATGATACAGATATGCGATACTTCAGAGAGGATTGAGCTTTTCATTGAAATGCTCAAAAGTGTCAGCATAGTAGAAATTGCAAGAACAGGGACAGTTGCGCTTACCAAGTGCAAGGAGCAGTGACTATATAATTGACATAGTGAATTTTCAAGTGGATTTTTTTGTCATTCTGATACAAATGACAAGATAATCCACTTTTGCTATACCAGGCCCATTTGATAAAATGATGCATATGAAAAAAGGTAATGAGGATATATATCAAAAAAGAATAAACAGACAGTATCTGACTCTTGTCTTTACCCTTGTGTTTGTAGTAACTACTCTTATTGCAGGGTCTTTGTATTTCAGATTCTACAGAGCAGGGATAACAGGCAAGGCGGAGGGCAATGAATACGAGCAGTATTATGTGATGATCACAGACAACTACAAGTCGGATTTCTGGCAGTCTGTATACAGATCAGCGCTTGAATTTGCCAAAGAGAACAATATTTATGTGGATCTTTTGGGAGAGAATCTTTCGGGGGATTATTCCTGTGAGGAGCTGATGCGAATAGCAATAGCATCCAGAGTAGATGGAATAATCGTCTATGCCAGTGAGGCAGTATCCATGACTAATCTGATCGATGAGGCGGTCAGGAGCGGAATACCTGTGGTGACTCTGTATGGTGACAGTACGCATTCAGACAGGATCAGTTTTGTTGGCGTTGGCGGCTATAGTGTAGGTAAGCTATATGGCAAGCAGATAGTCAGGATCATCAAGGAGAACAGAAGGCAGGAGCTTCTGGAATCAGAAACGATAGGGGACAGGACCAAGATCCAGATAGCTGCTTTAGCAAATTCTGATACTCTTGATGCCGGACAGAACATCATCATATCGTCAATGCAGGATACGATCAGACAGGAAAATGCTACGGATTCTGAGTTTGAGGTTTCAATTGTAACTGTCGATAATACTAATACCTTCTCAGTAGAGGAATCGATCAGAGATATTTTTATGCAAAAAGATGTCCCTGATGTAATAGTGTGCCTTAATGAGCAGAGCACAGTCTGCGCTTATCAGGCAGTTGTAGACTACAATATGGTTGGAGATGTCAATGTCCTTGGTTACTATGATTCGGAAGAAATAATCAAGGCAATTGACAGAGGAGTTATTTTTGCGACCATTTCTATTGATACTGATCAGCTGGGGACATACAGTATTCAGGCGCTGATGGACTATTATGAATATGGAAATACAAGTGAATATTACACTGCAGATATAACACTTATTGATAAAGATAATGTATATGAGTTCAAAAAACAGGAGGAGCAGGATGAATAGATTTTTTAACAGCTCTCTCCAGACCAAGATCATAAGTGTTTGTGTGTTTGCTAATGTAATTATCTTTGTGGTAAACATTTTTCTTTTGCTGGGAATTAACAGTATGTCCAATGATATGGACATGGTATATCAGGATAACAGGGCACTTAATGAGCTTACCAAAGCTCTTGATGAAGTTCAGGACTCGATGACTCTTTATCTTAGTTCCAAGACAAGTGATTCCCTGGAAAACTACTATATAAGTGCCCAGAAATTAACGAATCTATCAGGTGAGCTTGATGATAAGATAACTGACCTTTCTTATAACCGAATGGAAAGAAATATCAAGTACATGACAGGCAATTATCTTGGTGAGGTTGAGAAGACTATAGATACCAAGAGAGGCAGAAACGTCGAAAAATACAGAGCCTATTATGAGAAGTCCACAGAACTGTATAAGGATATCAAGGCCTATCTTACCAGCCTTAACCTTGAGCTTTTTGTATCCAATTCAGAGAGCTTTAACACTCTTATCAAGGCCTTTAGATACTTTGAAGTAGTCGCTGTCGGAGTCATGTTCATTGTAATGATAGGCAACGTGTTTATTATTACAAGCTTTGTTAAGACTATCATTTTACCGCTTAAGAAGTTATCTGACTCAGCGGATGAAGTTGCAGACGGTAATTTTGATATCGTTCTTCCTACAGCCCATTACAACGACGAGATAGGCATTGTTATTGGTGCCTTTAACAAGATGGTCATCAGTATCAAGGACTATATCGAGAAACTTAGAGAGAGCCTTGAGAAAGAGAAAGATATGCAGGAAAAAGAGCTTACAATGGAAGCTCACCTCAAGGATGCCCAGCTTAAGTACCTTAAGGCTCAGATAAATCCGCATTTTCTTTTTAATACCCTTAATGCCGGGGCTCAGCTTGCCATGATGGAAGGCGCTGACAGAACTTATGAGTATGTTCAGACTGTGGCTGATTTCTTCAGGTATAATGTCAAAAACCGTCAGGATACAGTTAATGTCCGCGAAGAAGTTACTCTTGTCGACAACTATATCAGGATACTTAATGTAAGGTTCTCAGGGGATATTGGCTATGACAAGCAGGTAGATGAGAGGCTCCTTGACCACAAGATGCCCAGTATGATCCTGCAGCCTATTGTTGAGAATGCTGTTAATCATGGAATAAGAGAAATGGCAGGGGATGGCAGGATCCTTCTTAAGGTTTACAGGGAAGATGACAATCTTTGTATCAGCGTTATAGATAACGGCAAGGGAATGGATGAAAAGACCATAGAAGAGATTCTCTCCGGAACCAGAAATCCTGATGAGAACAGCTATGACAACAACGGCATTGGAATGGACAATGTTATATCAAGACTTCGCCTGTTCGCAGGAAGAAGAGATGTTATCAGTATAAAGAGTGAAGGTGAAAACAAGGGGTGCGAGATAAAACTGAGCATTCCCCTTGAGGAGAATTAGTAAATGTATAGGGTAATGCTTGCAGATGATGAAGGAATCGTGATTGATTCTACTAAGTTTATTATAGAAAAAGAATTCGGAAATACATGTCAGGTGGAGTTTGCCAAGTCGGGGCGAAAGATGATAGAGCTTGCTGAGACTTTCAGACCGGATATAGCAATTGTAGATATCCATATGCCCGGTATAAATGGTATTGATGCCATCAGAGAGATGCAGAGATTTAGCAGTAATACAGTATTTATAGTAATGTCTGCCTATGACAAATTTGATTACGCCAAGGAAGCCATTAAGCTTGGAGTTCTTGAATATATTACCAAGCCCATGGATAAGACCAAGGTTATAAGTGTTCTTAAAAAGGCAATGGAGCAGATAGATTCAGACAGGGAAAAGAGGAGCAATGAACTTCTCATTAAAGAAAAACTGGAGACTGTAGAACCTATTATAGAGAACGGACTTATTTATGACATTCTTTTGCAGGAGCATTTCGAGGAAGATATAGACAATTACAGAACTATTCTGGGAATAGAGGAAAGCTATGGATACATGATGGCGATAGTATGCGGAGATTCTCAGGAAGGAAATCACATGACTAATGCTATCGGAAGTTCTGTCAAGATCTCCGGTAAGTATCAGGAAATAAGAGAAGGGGTCAAGAACTTCTTTGATTGCAAGATAGGTAATGTAATGGCTAATAAAATAGCTGTCCTGATTCCTCAAAAAGAGCCGCAGATGGAACTGGGACTTCGCTCAGAGCTTATAGACAGAGCAAGGGAAATGGCCAGATATCTCAGAAAGAAGACGGATATCAGCTTTAGAGTAGGTATTGGAGGAGTTAAGCCTTTAAAGGAACTTGGAGATTCTTACAAGGAAGCTCTTAATGCACTGATAGCTACAACCGGATCAGTAGCTCATGCAGATGACCTTACAATTAATTGCGATTATGAGGATGGATATCCTAAGGCTCTTGAGAAGCCTCTTTTTGAAGCCGTAGGTAAAGGCGATCTTAATGAGACCAGAGTTATAGCTGAGAAGTATGCTGACTGGATGTGCCAGAAGGCAGCAGATGGTGATCTTATGTCGATGAGACTCAAGGTTTTGGAGTTTTCACTTTATGCAGAACATCTTGCTTATCAAAATGGTGGTCAGACCTACAGATATTCCAGCAGGAACAATTATCTTCCTGAAATAATGGCTCTAGAAACTCCTATGGAGATAAGAGAATGGTTTATTTCCAAGGTTATGGCGGCCTGTAGCGATGTCATCAGTAAGAGACAGGAACGCTCAGGTAATATCATCAAGACTGCCAAGGATTATATTGATGCACATTTTGACAAGGATATTTCTTTGGACGATGTATCAAAGGTAGTAAATATTTCACCATATTATTTCAGTAAGATTTTTAAGGAAGAGAGCGGACTTAATTTTATTGAGTATCTGACTAACATCAGAATAGAAAAAGCCAAGAACCTATTGGAGAATTCTAATTTGTCCGTTAAAGAAATATGTATATCCTGTGGCTATTCGGACCCTAATTATTTTAGCCGCAGCTTCAAGAAAAATGTGGGAGTTACACCAACAGAATATAAAGACAGATTTTAAGTGGGGCAAAGGGTATGGGAAAGAAAAGGTTTGTATTAGGGTGCTTGATAGGTTGCTTACTTACAGCTTTATTATCCGGATGCAGTAGCCCTTCAAGAGAAGCTGAGAATTCCGGAAAAGAGAAAAGTGACAAGGTGCAGATAGGAATGTGCTTTGATTCTTTTGTCATAGAGAGGTGGCAAAGGGACAGGGATGTATTTGTTTCTACAGCCAAGGAACTGGGGGCAGAAGTTAATGTTCAGAATGCTAATGGTGACCCGGCCAAACAAAAGGAACAGATAGAGTATTTCATCAAAAAGGGGATGGATATTATAGTCATTATCTGTATTGATTCAAAGGAGATAGCAGATTCGGTCAAGAAGGCCCAGGATGAGGGAATCAAAGTTATTGCTTATGACAGACCGATTTCAAATGCCGGAGCAGACCTCTACATATCTTTTGATAATGAGATGGTTGGAGAGATGATGGGAGAGGCTTTTGTTAAAAATGGCTTAAAGGGCGGCAAGGTGGTAATGATATGCGGCCCGCTTACAGATAATAATGTTCCTATGGTTCGTGATGGTTTCACAAAAGTCATGGAAGAAAATGACAATGAAGTGCTTGATATCTATTATGCAGATGGATGGAAAGCAGAGGCAGCAGGGGATTACGTTTACAATAACACTGAGCTCATAGAAGAAGCAGATGCGATCATGTGCGGCAACGATGATCTGGCGAGCAAGGTGGTATATGCTCTTTCAGAGAAGCGGCTTGCGGGGAAAAAGATGGTATCCGGACAGGACGCAGATCTTGAGGCCTGCCAGAGGATTGTTGAGGGAACTCAGCTGATGACTGTTTATAAGCCTATTGAGAAGCTTGCGGGGAAGGCAGCAGAGGCAGCAGTCGCTCTTGCAAATGGAGAGGAGCTACCCGCCGAGGAATTATCTGAGTATGATGATGGTAAAAAAACAGTTCCTTACCTCAAGATAGAGACGGTGAGTGTTTCAAAAGACAATATGGATGATGTTATTATTAAGAACGGATTCCATTTAAAAGAGGATGTTTATTTGAATGTTCCACATTAAATAATGCTGCCTGGAATATCGCAAGATATTACGAAATAGCACAAAATTGTGACGATACAGCAGTGCCTGCAAAATAATGCTAGCACTGCTGTTTTTTTATTCTGATGGATAATAAAAATTTGCTTAATAATGCAAGTTAGTGCTTGTACTTGTGTGATAAATTGTTAAGCGTAGGGAGGCATGAGTCATGCCAAACTATTAAAAGTTTATAAACTTATAGCATATTTTTGACGGAGGAAAAGAGATGAAGAAAAAGTTATTTAGCGTAATGCTCGCTGCAGCTATGGCAGCATCACTCCTTGTTGGATGCGGAAGTCAGGCTCCTGCAAGCTCAAGTGGCGGTGGAAATGGTAAAGTTGGTGTGGCAATGCCTACCAAGGATCTTCAGAGATGGAATCAGGACGGTGCAAACATGGAGCAGCAGCTCAAGGCAGCCGGCTACGATGTTGACCTTCAGTATGCTTCTAATGATATTGCAACTCAGGTTTCTCAGATTGAGAACATGATCAGTTCAGGAGCTAAGGTACTTGTAATTGCTTCTATCGATGGCGATTCACTCGGAACAGTTCTTGCACAGGCAAAAGAAGCCGGCATCAAGGTTATCGCTTATGACCGTCTTATCATGAATTCTGACGCTGTTTCTTATTATGCAACATTTGATAACTATATGGTAGGAACCAAGCAGGGCGAGTACATCAAGCAGCAGCTTGATCTCGACAATGCAGCAGGTCCTTTCAATCTTGAAATCTTCACAGGTGACCCTGGTGACAACAATGCAAGATTCTTCTATGGCGGTGCTATTGACGTACTTAAGCCATACATTGACAATGGCAAGCTTGTAGTTAAGTCTGGTCAGGTTGATTTTGATAATGTAGCAACAGCTAACTGGTCAACAGAAAATGCTCAGTCCAGAATGGATGCAATCATTTCTGCTAACTATGCTGATGGAACTAAGCTTGATGCTGTTCTTTGCTCAAACGATTCAACAGCACTCGGCGTTACAAACTCTCTTGAAGCTAACTACACAGGCGACTGGCCAATCATCACAGGTCAGGACTGCGATATTGCTAACGTTAAGAACATGATTGCTGGTAAGCAGTCAATGTCTATCTTCAAGGATACTCGTGATCTTGCCAAGAAGACAGTTGAAATGGTTGACGCTATCATGAAGGGAACAGAAGCTCCTGTTAACGATACAGAGACATACAACAACGGCACTGGTGTTATTCCTTCATACCTTTGCGAGCCTGTATTTGCTGATGTAAGCAACTACAAGGAACTTCTTATCGATTCAGGTTACTACACAGAAGATCAGCTCAAGTAAGCGATAAATAGGTAACAGAATGGGATGCATAGCATGCTAGCATGCATTATGCATCCCATTATAGTTACTGTAACGGATATGAGTAAATAGCACGATAGTGCGGTTTACGAATGTCCGTCAGATTGCGGGAGCAAAGCGGAGCAATCTGTTTATCGCTGCTAACAGTAAAAAAATAGAAAAGGAGGAGGGGCAAAGGTGGAAAAGATAATACTGGAAATGAAGAATATCACCAAGACCTTCCCTGGGGTTAAGGCACTTGACAATGTTAATCTGAAGGTGTCGGAAGGTGAAATTCATGCACTTGTTGGAGAAAATGGTGCAGGTAAATCTACGCTTATGAACGTCCTTAGTGGAGTTTATCCATATGGTTCATATGAAGGCGATATTATATATAATTCTGAAGTCTGCCAGTTCAACGCTATCAAGGATAGTGAAGAAAAGGGTATTGTAATCATTCATCAGGAGCTGGCTCTTATTCCGTATATGTCAATTGCGGAGAATATGTTCCTTGGAAATGAGAGAGGAACAAAGTTTAAAATCAATTGGAATGAAACTAATGAACTTTCAAGAAAGTTCTTGAATATAGTTGGATTACATGAAAGTACACAGACACTTATAAAAGATCTTGGTGTAGGTAAGCAGCAGCTTGTTGAGATAGCTAAAGCTCTTTCTAAAGATGCAAAACTTCTTATTCTGGATGAGCCTACGTCATCTCTTAACGAGACTGATTCCAAGGCACTTCTTGATCTTCTTTTGAAGCTGAAAAAAGAAAGAAATCTTACTTCTATCATTATTTCTCATAAGTTAAATGAAGTATCTTATGTTGCAGATAAGATCACTGTTATCAGAGACGGATCTACGATAGAAACACTTGCCAAGGGAGTGGATGATTTCTCCGAGAGCAGGATCATAAAAGGAATGGTCGGAAGAGAAATCTCAGACAGATTCCCAAAGAGAGAATCACATCTTGGCGAAGTTATGATGGAAGTTAAAAACTGGAATGTATATCATCCGCTTCATAAAGACAGGAAAGTAGTAGATAACGTAAATATCAATGTCAGAAAAGGAGAAGTTCTGGGAATATCAGGACTTATGGGAGCGGGCAGAACAGAGCTTGCTATGAGTATTTTTGGCAGGAGCTACGGAGAAAACATTTCCGGACAGATATTTATAAATGGAAAAGAAGTTGAACTTAAAAATGTAAACAGTGCTATCAAACACGGACTTGCTTATGTTACCGAGGACAGAAAGGGGAATGGACTTATTCTTTCTAATCCTATCAAGATCAATACGACCCTTGCAAACCTTGATGAAGTAAGTACCAATAAGGTAATCGATAAGCATAAAGAATACTCTGTAGCTGTAGAGTATAAAGATAAACTCCGTACAAAATGTCCTACAGTTGAGCAGAACGTTGGTAACTTAAGTGGAGGCAATCAGCAGAAAGTTCTTTTGGCAAAATGGATGTTTGCTAATCCGGATATACTGATTTTGGATGAGCCCACAAGAGGTATTGATGTAGGCGCCAAGTACGAGATTTACTGTATTATCAATCAGCTGGTAGCTGAGGGAAAAGCTGTGATCATGATTTCATCGGAGCTTCCTGAAATACTGGGAATGTGTGATCGAATTTATGTAATGAACGAAGGCAAGATGGTAGGGGAAATGGATGCCAAGGATGCAACTCAGGAAAAGATCATGGCTTGTATCTTGAAATCTGCCGATGTTAAGGAGGAGAAACATGAATAAGGATAAAGTTTTTGAATTTTTGAAAAAGAACACTATGATCATAGTGCTTCTGATAGTTTTGGGATTCTTCTCATGGCAGACGTCCGGAGCAATTCTTCTGCCAATGAATGTTAGTAACCTTATTTCACAGAATGCATATGTATTTATTCTTGCAACAGGTATGCTTTTGTGTATACTGACTGGAGGTAACATTGATCTGTCAGTTGGATCGGTAGTTTGCTTTGTAGGTGCTGTCGGAGCTATTCTAATGGTAAACTTAAATGTTCCATTCTGGGTAGCAATCATAGTAATGGTTATCATCGGAACAGCAATTGGTGCTTTCCAGGGCTTCTGGATTGCCTTTGTAAGAATTCCTCCTTTCATTGTTACACTGGCTGGAATGCTTGCATTTAGAGGACTTTCAAATGTTGTCCTTAACGGACTTACAGTTTCTATCAAGGAACAGACTACTTTTGTAAACCTTTTTGGCGGCGGTGCTGACTGCTATATCCGTGATTTCTTTGGCGGTGAAAGCCTTAATCTTACCTGCCTCTTTGGCGGAATCCTTGGTGTGATCGCTATACTGTCACTTAATATTTACAGCCGTAAAAAGAAGATTGACAGTGGATATGAAGTAGAGGCTTTATGGGCATTTTGTTCCAAGATAATCCTGATCTCGGCTGCAATTCTTGTATTTGCTTATAAGCTTGCTCAGCACAAGGGTATTCCTACAGTTCTTATATGGGTACTCATCGTAGTTATTATTTATGGATATATCACAAGCAATACCACAACTGGCCGTTATTTCTACGCTGTTGGTGGCAACGAAAAGGCTACAAAGCTTTCAGGTATTGATACAAACAAGGTTTACTTCCTTGCATACATGAACATGGGATTTTTGGCAGCACTTGCAGGTATGGTTACAATTGCAAGACTTACATCAGCTCAGCCAACCTATGGACAGAACTACGAGATGGATGCTATTGGTTCCTGCTTTATCGGTGGCGCTTCTGCTTATGGCGGAATCGGTACTGTTCCGGGGGTTATTGTAGGCGCGGTTCTTATGGGTGTTATCAACCTTGGTATGTCACTTATGGGTGTCGATGCCAATATGCAGAAGGTTGTAAAGGGCGTAGTTCTTCTTGCTGCAGTAATCTTTGATGTTGTATCAAAGCGTGGCGGTAAGATGATCGTCAAGAATTAAGCTATCAGAATATTAAATAAATATAAATTTTTACAGGGAGTGCATGAGTGATATCAGCACTCCCTATTTATCTGCATTTACAGCGGCTTGAAAAAAGGCCTGACATCAACCTGATAATAGTATTACGATAGTAAATAATTGCAAATATGTTATAATTACTTTGGCGCGATAGTCTTATTGATAGAAGATACCCAGTAGTTATCTAATGGGGGTAGAACAATGAATGATAATCTGTTTCACATAGCATTTTATTGTGCAACGATTCTGGTGGGACTTACAGCCATTATCTATACTAATTTGCAGAAACGAACGGATCGTCGTCAGAACAGGATATTTCTTTTTATGAATTATGTTGTTCTTTTTAATGCGATCACATGTCTTTGCAGCGAATTTATTGAATTATACCGGCATTTCTTTTTAAGAGGTGATGGACTTATAATGTTGTTCCAGTATGTATACTTCCTGGTACATACGCCGATTGCCGCTATTTTTCTATACTATGTCTTGACTGTTACAGGGTCGATCCGGAATAAATCTGTTTTTTCTAAAATTTTATATCTGATTCCGCTTTGTTTAACGGAGTTTCTGGTTTTAACAAATCCTGTTACTCATTTTGTTTATTATTATTCTGAGGGCATGCAGTTTAACAGAAGCTGGGGCGAGATAATCATCTACTTAGTCTCTATTGCTTATACTGTGTTTGCTTTCATATGCCTTATGATGTCATGGAATGCACTCACAAGGCGTAGAAGATGGGCTATTGTATACTTTTTTATCCTTACCATAATCGGCGTTGTTGTACAGTTTCTGGATATAAGTATAAAGAGTGAACTGTTCGCTGAATCTATAGCGCTCATCGGTCTTATGCTGGCTGTAGAAAATGAAGATGACAGGCTGGATGCAGAAACAGACTTCTATAACAGAAATGCCCTGAAAATGGATGTAGAAAGTCTTCTTACCAAAAAGAATGTATTCTACATAGTTTGCGTTAAGATCACAAATATAGATTCCGTGAGACGTATCACGGGACTGTCCAATGCGGATGAGATAGTCCAGGAGGTGGCAGTTTTCCTTAAAACTTTGCTTCCGAGATATTACATTTATCATACTGATCCCAATACCATGCTCCTATTGGTCAAAGAGGATGATTTTATTAACTCTGAACTTGAAGCGCTCACAATTGCAGAAGATATTGACTGCCGCTTTAAGTCAGAGTGGACAGTTCATGGGGTACAGATGAAGCTATCTGCAGTTACGATTGTAGCCAGTATCCCTATGCATATTCATACCCTTGCTGATCTTATGTATATGATTGATACACCTGTGCCCAAGGATATAGACCGCACTATTTTGAGAAACGGAGATCTTAAATTCCTTACAAGGAGAGCTGAAGTTGAAACTGCTATAACTGAAGGCCTTAAACAGGGGAACTTCGAAGTTTATTATCAACCTACCTATTGCTCTGATGGTGTGACTCTTCACGGGGCAGAGGCTCTTATAAGGCTTCATGATCCTAAACTTGGAGATCTTTTCCCGGATGAATTTATTCCTATCGCTGAGCAGACCGGATATATTGATGATATAGATGATTATGTTCTCAATGAGGTATGCGCCTTTTTGCAGAGCGGAGAGCCTACAAGGCTTGGAATGGAGTGCATTAATGTAAATCTTTCAGTTGTTCAGTGCATGCAGGATAAGTTTGTTGAGAGAATCAGAGGGATAGTAGACAGCTATGGAATCTCCAAATCACTTATCAACTTTGAAATAACAGAGTCTGTTTCTGCAAGCGATTATGAACTATTGAGCAAGGTTATCACGAGCCTTAAAGAAAATGGTTTTCAGTTCTCTATGGACGATTATGGAACAGGTTATTCAAATATGCATTCTCTTTTCTCACTATCATTTGATATTGTCAAAATTGATAAGAGTATTCTGTGGGATGCGGAAAACAGTGAACTGGGAGAAATTATATTAGAAAGCTGCATTCATATGATCAAGCAGATGAAGAGGAAAATCCTTGTTGAAGGTGTCGAGACAAAAAAACATGTTGAAAAGCTCAAAAAGCTTGGGGTTGACTATTATCAGGGATATTTCTTTTCCAAACCTATAACTAAGACAGAGCTGCTAAGCTACTGTATATCAAGATAAATAGCATATTGAGAAGGCAAGGAGGATTCTATGGAACTGACACATGAAGAAGAAAGTATTTTGTCGGGTATATCTTTTAACGGGGAACAGATCAAAAACGGGGAACTGGACGAAAATGACAAGGCTCTTTTGACTGAGATGAGAGCAGTTGGGGCTTATCTTAAGAAAAAATATCCCAGCTATGAATTTGTAATTACAGGATGCGAACTTAAAGCCGGTACTGCCAAGGATTACAATGAGTGGTATTACAGAGCAGAAGGAATAGAGCGGGATTCTGCTTTTATCGCAACAAGCCGGGAAATGGATGGAAAACTTGAGATAAAAGATGATTTTTACGGGGAAGTCGTAAGAAAAGATATTCAGGAAACGATAGAAGGTGACCTTAAACAGATTGGACTTCCGGTAGTCCAGGTAAACATTGGATTCTGGGAATATTTGGGAAAAGAGTACGGAGAGAAAATCTCTGCAGACGAGGTATTACAGGGAATTATTCCTGCTGGAAATGATATAAAGATCTTTCTTGACGGTTCTGTTCTTTCCGATGCTCCGTACGAGGAGGTAGTTGCAAAGATCAAAGAATTATTGGTCAGAAAGAAAGTGATTGGTGATATTTACATCGTTGTTCTAAAGGATGCCGATAGCGATTTTGCCAGGGACAGGTTGTATTCAAAGAGTGTGACGCTGGACTGAATTTGGGGGAAGTGTATGAACAGCAAACTTACGATTGAAGAAATAGTTCTTATCAATAACCTTCTTTATTGCGAAAACCTTGGAGGACCAAGGGGAACTTTTTTACATCCAAGTCAACAATCCAAGACAATAGGAGACTATGTCAGAGGAGTCCTTAGAAAAAGTGAAGATATTGAAGACGACACTGAGTATAGTACAGGAGTCACAGGTGCTGAGTACAAGGAAATACTACAGGCTGTTAAGGCAAATGAGCATCTTTGCGAGATTATCATTCAGGAAGTTCATTATGAAGGTGCAAATGTCGGCGGCGGAAGAAGCGCATTTTTGATAGATCCTGTATACAACGAGGCTATAGTTGCCTTTAAGGGAACACAGAGTGATGCGGAATGGATAGATAATGTATCGGGACTGTATACTGTTCCTACTGCCTTTCAGGAAAATGCCTTAAACTGGTACAGATCACTTGATCTTGATGGATACGATGCAATTACAGTAACCGGCCATTCCAAGGGCGGAAATAAGGCTAAGTACATTACCATCATGGACGATTCTGTAGATAACTGTTTTTCTTTTGACGGACAGGGCTTTTCTGATGAATTTATCCGCAAGTATTCTGCGGAGATCGTAAGAAACCGTGAAAAGATAATAAATATCATTGCAGAAAGTGATTTTGTAAACATTCTTCTAAATGATGTCGGCCCCAAGCAGTTTTACCTTGGAACTAATTTTGGAAGACTTGGATTTGCGGAAAATCACTGCGCCAATGCTATTTTGTTCTTTGATGATAAAGGGGATATGTATCTGTGGAAGGCCAAGGCACAGGATAAGAAAATGGCGGATCTTGATAAGATGCTTAACAGTTTTATCAGGACTTGCCGAATGTCTACCAAAGAAAACATTGCAAATATGCTCGGAAATGTAATAGTTAGTGCCAAGGCAGGAGATACGGAAGGACTTATAGCAACCTTCACCGACGAAAGGTATAAAGATAGTGCTGCCAGTCTTGCAGCTTATATCTTGAGATACAAGGAAGAAAAGCCTCAAATGGTAGCTTCTGTCAGAGAAATCCTTGGTCAGAACGGCTTTAATACAGGTATGCTCGGAATAATAGACTTTATAACAAATCATGAGTTTTTATTAGAAATGATAGGCAAGAATCCAAATGCCATGATAAGACTTTTGAAGATGAATCATGCACCTGAACCGGCAATTGTATTTTTAAGCAGTCATTTCGGACTCTTTTCTTTTATTGTCCTTGTGTCTGAAAAAATGCATATGCTAAAAGATATAAATCTTGAAGGAGAGGATATTGATCCTGAGGATGAAGTGATCACTATAGGTCAGAAGAGACGGTTTTATGTATCCAAGAGAACAGTCGGGATCATAGCTATCTGCATAATAGCAACGATAGTAATAATAGGCATGCTTGTAGCTATTATTATGTAAAATTATTATCTGTAAAAAGGATGTTAAAAAAATATCAAAAACCATTGAAAAACTAAAAGATTTGTGCAAAAATAAAAATGGTGTTCTGCGGTCGGCTTATTAACTGACACGTAAGAGCCATCTATGATTGTATGCGGCAGATTACGATTCATGCAATCATCTATAGGTAGTAAGTAATGAAAGTTACTTTACAATACGAAAGGAGATTTTTCACATGATTTACTCAACAGAGGTAAAAAATATGTGTCCCGTAACACAAGGGGTACATCATGGCGCTGCTCCCATTCCTGAAGAGGCTAAATGGGTAAAGTCCAAAGAAATTAAGGATATTTCCGGCTATACACATGGTATCGGCTGGTGCGCTCCTCAGCAGGGTTGCTGTAAGCTTTCACTTAACGTTAAGGAAGGCATCATTCAGGAGGCATTGGTTGAGACAATCGGATGTTCAGGAATGACACATTCAGCAGCTATGGCAGCTGAAATCCTTCCAGGACTTACAGTTCTTGAAGCACTCAACACAGACCTTGTTTGTGACGCTATCAACACAGCTATGAGAGAGCTGTTCCTTCAGATCGTATACGGCAGAACACAGTCTGCATTCTCTGAGGATGGTCTTCAGATCGGTGCTGGTCTTGAGGATCTTGGTAAGGGAACACGTTCTATGGTTGGTACAACATACGGAACACTTGATAAGGGACCTCGTTATCTCGAGCTTACAGATGGTTATATCACAGATGTTGCTCTTGATGAGAATGATGAGATCATCGGATATAAGTACGTTAACTTCGGCAAGATGATGGACTTCATCAAGGCCGGTGATGATGCTAATACAGCTATGGAAAAAGCTAAGGGTCAGTATGGACGTGTTGCTGATGCAGTTAGATGCATTGACCCTAGACATGAGTAATTAAGGTAAGGAGGAAAAAATAATGGCTTTATTTGAATCATATGAAAGAAGAGAGCCCCAGATCCTGGCTTGCCTTAAGGAGTATGGGATTTCTTCCATCGAAGAATGTAGAGATATTTGTATGAATGCTGGTATCGATGTTTACAAACTCATCGAAGGCATTCAGCCAATCTGTTTTGAGAACGCTAAGTGGGCTTACACAGTAGGTGCTGCTATCGCTATCAAGAAAAACTGCCGTAAGGCTTCTGAGGCTGCTGCTGCAATCGGTATCGGTCTTCAGGCTTTCTGTATTCCTGGATCAGTTGCTGATCGTCGTAAGGTAGGTCTTGGCCATGGTAATCTTGGTAAGATGCTTCTTGAAGAGGATACAGAGTGCTTCGCATTCCTTGCTGGTCACGAGTCATTCGCAGCTGCTGAGGGTGCTATCGGTATCGCAGAGAAGGCTAACAAGGTTCGTCAGAAACCTCTTAGAGTTATCCTTAACGGTCTTGGTAAGGATGCTGCTCAGATCATTTCTCGTATCAATGGTTTCACATATGTTGAGACAGAGTATGATTACTACACAGGTGAGGTTAAGGAAGTATTCAGAAAGTGCTACTCTAAGGATGCTAATTCACCTCGTGCTAAGGTTAACTGCTACGGTGCTAACGACGTACAGGAAGGTGTTGCTATCATGTGGAAGGAGAATGTTGACGTATCTATCACAGGTAACTCAACTAACCCTACAAGATTCCAGCACCCAGTTGCAGGTACATACAAGAAGGAGCGTACAGAGGCTGGTAAGAAGTACTTCTCAGTTGCTTCAGGCGGCGGTACAGGACGTACTCTTCACCCAGATAACATGGCTGCAGGCCCAGCTTCTTATGGTATGACAGATACTATGGGACGTATGCACTCAGATGCTCAGTTCGCAGGTTCTTCATCAGTTCCTGCTCACGTTGAGATGATGGGTCTTATCGGCGCTGGTAACAACCCTATGGTTGGTATGACAGTTTCAACTGCTGTATCTATCGAAGAGGCTGCTAAGGCTGGTAAGTTCTGATAGTTTATCAGATGATAATAATGGGGCTGTCGCACTAATTTAGTGTGACAGCCTTTTTAACGCCCAGCCCCTCAGGCATCCGCACAGAAATGATTGTTTTCGTCTGCGGTGTGATTTTCTAAAACTCATTAAGCATCAAATGCCTCATTTCGACGTTGCTCAGAGAAATCGGCATTTGATGCTTTCTTCGTTTTGAAAATCATCATCCTCGTCCGAGAACTGCACATTTCCATGCAGATGTCTGAGGGGCTGGGCTGCTAGTAAATATCTTCACATAAAGCAAAAACCAGACTTCGAAAAGCCTGGTTTTTACTGTAAAATATGTTTATGCGACTAAACAAAATCTTACAAGGAGATTATACAGTTTCTTCCTTGTATCATCAAATCAAACTTCCGCTCGACATAGAAATTTCTATCCCATCCGATGATCCGGTGCGCCTGTTAAGTGCATTTGTGGAGGAAATGAATCTTTCTGATCTGTATAAAACTTATGACAGAATCAGAAAAGGCCAGGCTTCACCGCGTCAGATGCTTAAGATTGTTATCTATGCAGCAATGAACAGAATCTATTCAAGTCGTGATATTGAGTCCGCCTGCAAAAGAGACATCAATTTCATGTACCTTCTGGATGGAGCACCTGCTCCAGACCATTCCACAATAGCAAGATTTATATCAATGCATCTTTCACAATGCGCTAAGCAGATCATGGCACAGGTAGGGACCATACTGCTCGAACTGGGAGAAATATCAGGCGAAAACATCTTTATCGATGGAACAAAGATAGAGTCAGTAGCCAACAAGTATACCTTTGTATGGAAAAAAGCTGTGTCCAAAAACATGATAAAGCTCACTGAAAAGATATGTGTTTTCTGCGCCGGATGTGAAGAACTTTATGGAATAAAAGTAGTCTATAACGATCAGATATCATTACATACCCTTAAGCGTCTTAGAAAGAAACTGTACAAGCTCAAGGAGGATGAAGGTATTGAATTCGTTCATGGAATTGGCAAAAGGAAAACTCAGTTGCAACGTTCGTTGGAAGCTCTTGAAGAATACATAGAAAAACTCAAAGAATACAACCATAAGCTTTATGTATGCGGCACCAGAAATAGTTATTCAAAGACTGATACCGACGCAACATTCATGAGAATGAAGGAAGATGCCATGCTCAATGGCCAGCTTAAGCCAGCATACAATCTGCAGCATGGCGTGGATTCAGAGTATGTCACATGGCTGGATGTCTTTCCGGCTCCAACAGATACCATTACATTGATACCATTTCTGAAAGACATGGAGTCACATCTTACATTCAAGTATAAAAACATCGTTGCTGATGCAGGATACGAAAGCGAAGAAAACTACATATTCATCGAGTCCAACGAGCAGGCCGCGTACATCAAGCCTCAAAACTACGAACTTTCAAAAACAAGGAAGTTCAGGAATGACATAAGCAGGCGTGAAAACATGGACTATGATCCTGAGTCAGACTGCTACACATGCAGAAATGGTCAACAGCTCCCTGCAGTATCCAAAAGAACACAAAAATCAGCAACCGGATATCAGCGTGAAGTTACGATATATGAATGCAGTAGTTGCAATAACTGCCCCTACAAGAAAGATTGCATTAAAGGGAATAACTGTAAGACCGCATTTGAAGATAGAAATAAAAAGCTTTCTGTCTCAAGAAAAATGGAAGAAAAACGAGCAGAATGTCTTGAACGGATAACCAGTGATTACGGAACACAGCTGAGGATGAACCGAAGCATCCAGGCAGAAGGATCCTTCGCAAATGTGAAAGAAGACATGAACTTCAGAAGATATCTGTACCGTGGAAAAGAAAATGTTCTTACACAGAGCATACTTTTGGCAATCGGCTATGACATAAATAAGCTGCATCATAAAATTGCTGATGAGCGAACAGGAACGCATCTGTTTGAATTAAAAAAGGTTTCATAA

Protein sequences of DBSCAN-SWA_1

>NC_014387|1385734:1458193|1389925_1391863_+|WP_013280526.1|DBSCAN-SWA
MMKFFKRKINYGQNNKSNKTDLIEAARSLMQDYWNTSANKIHFLVSRVTCRHIYLICMYEGNDLDINNLKTAEMIYMVKLLNLAGLENKEPNEEQEFLESSFYDFMENLRLARNIYSDLELAYNPLKIDLQQEVIPEKLFDTNIEPVEKAYSFIPSDELTRIRCSENTERDDVDRPVHYLVYSNNRKVIDEINEDLIYRLRKYKRITSRRYLEISRNNIKPRDKNNYRIGNLNNLDGGLVIVNLDDTVNDDFEVLVNSVYSEPGKYKGKYTVIFNLCEADDARVSVIKRICDFWSFVVISDGKLERAKAIKLLDQIAEENDVVLIDSYYDEILEPGKKYLRDELIAAFRKWYLNRYNIRKNYPAYTTYIINLSNVDELSCPSYHELESLIGLKNVKTLCKDIISFYQMEKLRKEKYSSLKDIGMHMVFQGNPGTAKTTVARIMARIFKEKGILSKGDLIEVGRANLVEKYVGQTAPNVKSYFEKAKGSVLFIDEAYSLADGEGKGSYGTEAINTIVQEMENNRDDVVVIFAGYKKEMKEFLKVNSGLSSRISFFVDFPDYSDDELFEILTKMAKDNHYTLADDVRSAFENYINSTVTSIGNGRFVRNAFERARIRQSSRICKLPVKQLTKELFVLSGQDFGGLHD
>NC_014387|1385734:1458193|1395856_1397890_-|WP_042256645.1|DBSCAN-SWA
MILSVHNINKSFDGKDILRNASFHIEKDEKAAIVGINGAGKTTLIKIIIGELSADDGDVTFSKDITWGYLAQNQNIDSENTIYEELVEVKKDVIDLENNIRLAEENMKHVQGAELEALMDRYTRMQDEFQRKSGYAWKSEVTGVAKGLGFLDEELDKRISTLSGGQKTRVALGKLLLQKPDLIILDEPTNHLDMNSIRWLENYLLNYKGAVLIVSHDRYFLDKISGKIIEVENTRVTSFTGNYSTYAVKKEQMRAIEWNAYIKQQAEIKHQEEVIAKLKSFNREKSIRRAESREKMLDKIEVLDKPITIDDRMKISLTPSCESGNDVLTATGLSKSFGNEHLFSNLDFEIKKGEHVAIIGDNGSGKTTLLKIINGVESLDAGQIDFGVKVHIGYYDQEHHVLHDEKTLFEEISDAYPTLNNTEIRNTLAAFLFTGDDVFKRIGDLSGGEKGRVSLAKLMLSDANFLILDEPTNHLDITSKEILETAISGYTGTVLYVSHDRYFINRTATRILDLTHGQFVNYIGNYDYYMEHVDEKMQRLFGTSGNIGNATLGDGSYKYANGAADLNDSDNASESASSLSSNAQSSDATAGGAMDWKAQKALQAQKRKLETALSKCEEDISKLEGRDGEITEQLSDPSVGTDLAKLRKLTDEQTEIQDKLSSLYDEWEKISSELSEF
>NC_014387|1385734:1458193|1447267_1448821_+|WP_013280568.1|DBSCAN-SWA
MEKIILEMKNITKTFPGVKALDNVNLKVSEGEIHALVGENGAGKSTLMNVLSGVYPYGSYEGDIIYNSEVCQFNAIKDSEEKGIVIIHQELALIPYMSIAENMFLGNERGTKFKINWNETNELSRKFLNIVGLHESTQTLIKDLGVGKQQLVEIAKALSKDAKLLILDEPTSSLNETDSKALLDLLLKLKKERNLTSIIISHKLNEVSYVADKITVIRDGSTIETLAKGVDDFSESRIIKGMVGREISDRFPKRESHLGEVMMEVKNWNVYHPLHKDRKVVDNVNINVRKGEVLGISGLMGAGRTELAMSIFGRSYGENISGQIFINGKEVELKNVNSAIKHGLAYVTEDRKGNGLILSNPIKINTTLANLDEVSTNKVIDKHKEYSVAVEYKDKLRTKCPTVEQNVGNLSGGNQQKVLLAKWMFANPDILILDEPTRGIDVGAKYEIYCIINQLVAEGKAVIMISSELPEILGMCDRIYVMNEGKMVGEMDAKDATQEKIMACILKSADVKEEKHE
>NC_014387|1385734:1458193|1450223_1452152_+|WP_013280570.1|DBSCAN-SWA
MNDNLFHIAFYCATILVGLTAIIYTNLQKRTDRRQNRIFLFMNYVVLFNAITCLCSEFIELYRHFFLRGDGLIMLFQYVYFLVHTPIAAIFLYYVLTVTGSIRNKSVFSKILYLIPLCLTEFLVLTNPVTHFVYYYSEGMQFNRSWGEIIIYLVSIAYTVFAFICLMMSWNALTRRRRWAIVYFFILTIIGVVVQFLDISIKSELFAESIALIGLMLAVENEDDRLDAETDFYNRNALKMDVESLLTKKNVFYIVCVKITNIDSVRRITGLSNADEIVQEVAVFLKTLLPRYYIYHTDPNTMLLLVKEDDFINSELEALTIAEDIDCRFKSEWTVHGVQMKLSAVTIVASIPMHIHTLADLMYMIDTPVPKDIDRTILRNGDLKFLTRRAEVETAITEGLKQGNFEVYYQPTYCSDGVTLHGAEALIRLHDPKLGDLFPDEFIPIAEQTGYIDDIDDYVLNEVCAFLQSGEPTRLGMECINVNLSVVQCMQDKFVERIRGIVDSYGISKSLINFEITESVSASDYELLSKVITSLKENGFQFSMDDYGTGYSNMHSLFSLSFDIVKIDKSILWDAENSELGEIILESCIHMIKQMKRKILVEGVETKKHVEKLKKLGVDYYQGYFFSKPITKTELLSYCISR
>NC_014387|1385734:1458193|1387076_1388102_+|WP_143754269.1|DBSCAN-SWA
MENYDFTGNALLEPEDTVLYGITCGICLLTRATNAMPLVGGAIVIILVSIRSKAFTNLLKNIMFFVIAMGIVVAPFCIYFLIKGSTAEMFFAMITYNKEYAALRRPWIIESNARDIVRFFHLYFSVFSILLVAVVNWFNRQYAKFAFSFITFGIELFFYMSNDLFVQYPMVCATQVILLCYEIEKLYRNKILIGAKINVPIFIAICTLLFSVGSFCKTAILDDFIAHIFVYGNYSYYCTEPWEELVDMIPDKKEPFVTYGSNDLKPVYVLKDIDPCYKYFSIQPWHSMYDASIAEEIRAQMLSNKAKWILCDEVGRDTILSLNTNYYIYAENGGFSLLECK
>NC_014387|1385734:1458193|1441609_1443085_+|WP_167531153.1|DBSCAN-SWA
MNRFFNSSLQTKIISVCVFANVIIFVVNIFLLLGINSMSNDMDMVYQDNRALNELTKALDEVQDSMTLYLSSKTSDSLENYYISAQKLTNLSGELDDKITDLSYNRMERNIKYMTGNYLGEVEKTIDTKRGRNVEKYRAYYEKSTELYKDIKAYLTSLNLELFVSNSESFNTLIKAFRYFEVVAVGVMFIVMIGNVFIITSFVKTIILPLKKLSDSADEVADGNFDIVLPTAHYNDEIGIVIGAFNKMVISIKDYIEKLRESLEKEKDMQEKELTMEAHLKDAQLKYLKAQINPHFLFNTLNAGAQLAMMEGADRTYEYVQTVADFFRYNVKNRQDTVNVREEVTLVDNYIRILNVRFSGDIGYDKQVDERLLDHKMPSMILQPIVENAVNHGIREMAGDGRILLKVYREDDNLCISVIDNGKGMDEKTIEEILSGTRNPDENSYDNNGIGMDNVISRLRLFAGRRDVISIKSEGENKGCEIKLSIPLEEN
>NC_014387|1385734:1458193|1455217_1456237_+|WP_013280574.1|DBSCAN-SWA
MALFESYERREPQILACLKEYGISSIEECRDICMNAGIDVYKLIEGIQPICFENAKWAYTVGAAIAIKKNCRKASEAAAAIGIGLQAFCIPGSVADRRKVGLGHGNLGKMLLEEDTECFAFLAGHESFAAAEGAIGIAEKANKVRQKPLRVILNGLGKDAAQIISRINGFTYVETEYDYYTGEVKEVFRKCYSKDANSPRAKVNCYGANDVQEGVAIMWKENVDVSITGNSTNPTRFQHPVAGTYKKERTEAGKKYFSVASGGGTGRTLHPDNMAAGPASYGMTDTMGRMHSDAQFAGSSSVPAHVEMMGLIGAGNNPMVGMTVSTAVSIEEAAKAGKF
>NC_014387|1385734:1458193|1385734_1386853_-|WP_013280040.1|transposase|DBSCAN-SWA
MNNITVYVGMDVHKESFTLCDYLIETEKASHTRRTHADYKEVLKYLEFLRTIYGNDTNFICGYEAGCLGYTLYHQLTNHNVNCVILAPTTMLEPRSGKRIKTDKRDAELIGKCLAQHNYSPVHVPTSTDEETKEFLRMRDDHKLALKKVKQQILSFCLRHDYRYEGKSHWTEAHVNWLKSLKPEALYKEILDEYLLTYINLRDKLERLDKRIEELALKDEYREPVKKLCCFIGVQTHTALSVLVEVGDFKRFASANQFAAYLGLVPGEESSGDEKSRLGITKAGNRHVRQLLIESSQSYSKGQIGHKSKALKSRQIGNSPQVIAYADKANERLRRKFYKMVLGKSKKHNVAKTAIARELACFMWGMITDNIA
>NC_014387|1385734:1458193|1392351_1393470_-|WP_013280040.1|transposase|DBSCAN-SWA
MNNITVYVGMDVHKESFTLCDYLIETEKASHTRRTHADYKEVLKYLEFLRTIYGNDTNFICGYEAGCLGYTLYHQLTNHNVNCVILAPTTMLEPRSGKRIKTDKRDAELIGKCLAQHNYSPVHVPTSTDEETKEFLRMRDDHKLALKKVKQQILSFCLRHDYRYEGKSHWTEAHVNWLKSLKPEALYKEILDEYLLTYINLRDKLERLDKRIEELALKDEYREPVKKLCCFIGVQTHTALSVLVEVGDFKRFASANQFAAYLGLVPGEESSGDEKSRLGITKAGNRHVRQLLIESSQSYSKGQIGHKSKALKSRQIGNSPQVIAYADKANERLRRKFYKMVLGKSKKHNVAKTAIARELACFMWGMITDNIA
>NC_014387|1385734:1458193|1413287_1414151_-|WP_013280543.1|DBSCAN-SWA
MSFTVFADGCANLPQKIASEIVILPCNYLVNGTQKVYSGDIDNFDGHTYYEGLRNGDLIQTSLLNTQLFIEHFTPYAQEGKDIIYISMSSGISGTYNAARIAADELMEEYPDCFIHIVDSHGCGFGNGILALKAVDLARKNVNARNAADILDEAVPHACQYFTVDDLNFLKRTGRVSGVTANIGTILNIKPILFGDSTGHIISCNKVRGRKNAISELAKKYAEKRMEDEKQIVFISHGDCLDDANKLADMVKEINPRAQVTICMHEPFSGSHVGPGMLGLFFWGNER
>NC_014387|1385734:1458193|1444698_1445748_+|WP_013280566.1|DBSCAN-SWA
MGKKRFVLGCLIGCLLTALLSGCSSPSREAENSGKEKSDKVQIGMCFDSFVIERWQRDRDVFVSTAKELGAEVNVQNANGDPAKQKEQIEYFIKKGMDIIVIICIDSKEIADSVKKAQDEGIKVIAYDRPISNAGADLYISFDNEMVGEMMGEAFVKNGLKGGKVVMICGPLTDNNVPMVRDGFTKVMEENDNEVLDIYYADGWKAEAAGDYVYNNTELIEEADAIMCGNDDLASKVVYALSEKRLAGKKMVSGQDADLEACQRIVEGTQLMTVYKPIEKLAGKAAEAAVALANGEELPAEELSEYDDGKKTVPYLKIETVSVSKDNMDDVIIKNGFHLKEDVYLNVPH
>NC_014387|1385734:1458193|1440528_1441617_+|WP_042256664.1|DBSCAN-SWA
MKKGNEDIYQKRINRQYLTLVFTLVFVVTTLIAGSLYFRFYRAGITGKAEGNEYEQYYVMITDNYKSDFWQSVYRSALEFAKENNIYVDLLGENLSGDYSCEELMRIAIASRVDGIIVYASEAVSMTNLIDEAVRSGIPVVTLYGDSTHSDRISFVGVGGYSVGKLYGKQIVRIIKENRRQELLESETIGDRTKIQIAALANSDTLDAGQNIIISSMQDTIRQENATDSEFEVSIVTVDNTNTFSVEESIRDIFMQKDVPDVIVCLNEQSTVCAYQAVVDYNMVGDVNVLGYYDSEEIIKAIDRGVIFATISIDTDQLGTYSIQALMDYYEYGNTSEYYTADITLIDKDNVYEFKKQEEQDE
>NC_014387|1385734:1458193|1452182_1452842_+|WP_013280571.1|DBSCAN-SWA
MELTHEEESILSGISFNGEQIKNGELDENDKALLTEMRAVGAYLKKKYPSYEFVITGCELKAGTAKDYNEWYYRAEGIERDSAFIATSREMDGKLEIKDDFYGEVVRKDIQETIEGDLKQIGLPVVQVNIGFWEYLGKEYGEKISADEVLQGIIPAGNDIKIFLDGSVLSDAPYEEVVAKIKELLVRKKVIGDIYIVVLKDADSDFARDRLYSKSVTLD
>NC_014387|1385734:1458193|1404062_1404761_+|WP_143754270.1|DBSCAN-SWA
MLSFRRALIHFPRSIFDLYKVVLFDTILTGDFDMNIVCLDLEGVLVPEIWIAFSEASGIPELKKTTRDEPDYDKLMKWRIGILKEHGLGLKEIQDTIKKIDPLPGAKEFLDELRKITQVIIISDTFTQFATPLMEKLGWPTIFCNSLEVADNGEITGFKMRIEQSKLTTVKALQSIGYETIASGDSYNDLAMIQASKAGFLFRSTDKIKADYPELPAFEEYDDLLAAIKNNL
>NC_014387|1385734:1458193|1429023_1429500_+|WP_013280553.1|DBSCAN-SWA
MLEFSFVNIICVIVNILILYLIFKKFLFGRVDKVLMQRKEEIDEATKAADLATKKALETKKEYEDKIALADEEKEQILADIKKQGYDEYDRIVNDAKKKGEKIITEAKHNAEVENERAKEVYAAQLTDMVIDAASKIAATKHSTQDDRELYDKFINEA
>NC_014387|1385734:1458193|1423420_1425223_+|WP_013280549.1|DBSCAN-SWA
MDKKHGSLMLPIVGSIILAVVITAVAIAGFNIYSSINTNKSQTEAYKARLLEDVQAELKNETQEAMSICQVMYDRYLAGEMTMEEAQKEAADIIRELKYNDGAGYFWVDTSKGINVVLLGRDTEGQSRWDSVDPNGTYFIQEMIKNGLQEGGGYTNLMFAKPNETEPLPKINYTAYFEPFDWVMGTGVWVDHLDSLAAEYIGHATMDMYRNINSSIITMLVLLVIGISIAVYMGKRITKPLILATEQMVRMSNNDFTDNEEMEKVRSLPAKENNEIGQIAEALDLMHKNIRDLMMKISDTTAYVASASEELSASASQSAQASEMVANSCTNVANSCSGQITAVSGASNETKAFVNNMQEFQDAISRTTEMIDTTNDAATKGAADMTNATNMMKTIKDSVENTASVVETLGEQLKNIDSFVDTIAEIASQTNLLSLNASIEAARAGEMGKGFAVVASEISKLADQSNEAASKITELIAEIMQNSNEAVEAMRSGAQSVVEGTETVNEAGNTFGNIVEMVYSISEQSARMSEIVGQLSEGTETIAENIQKIENMSADVADETQNVSAASEQQTASTHEVAEASDRLAENAQELQNFVAKFDL
>NC_014387|1385734:1458193|1428050_1428740_+|WP_042256660.1|DBSCAN-SWA
MNIKELLKEILLKDKAFIHLPFGNGKYDIYESVVVMWIIMAILFIALLILTRDFKVHNISKRQAAIESFVVWIRKIIGGSLGEKGERYTDYIVSILIFLGAANMIGLLGFIPPTMDINVTAALAFMSIVLVEVAAIREKGAKGWLKGFAKPMAIVLPMNIMELAIRPLSLCMRLFGNIIGATVIMELIKMVLPAVLPVPFCLYFDIFDGLIQAYVFVFLTSLYINEAVE
>NC_014387|1385734:1458193|1429489_1431304_+|WP_013280554.1|DBSCAN-SWA
MRLEQIMSEKLLAKLRYASTSPTPEQVNGIKAMLCKKFNVDDIELELSEDKSIGGGFIVSCKNYEYDWSDAGRAKQLRAEINNLRREHGGNDAGKIISMLSDKVENFDLAVEDKEVGSVVWVGDGIANIDGIEHAFYGEIIEFEDGTKGMAQDIRDDHIGCILFGNDAGIRQGTRAVRTYKEAGIPVGEAFIGRVIDALGAPIDGQGDIKESGYRPVEGPAPGIIDRQSVNEPMETGILSIDTMFPIGRGQRELIIGDRQTGKTSIALDTIINQKGKDVICIYVAVGQKASTVAKIIQILKKTGAMDYTIVVSSTASDSAPLQYIAPYSGTAMAEYFMHEGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSRLLERSSKLSSELGGGSITALPIIETLAGDVSAYIPTNVISITDGQIFLESDLFFEGMRPAVNVGLSVSRVGSAAQTKAMKKAAGSIRVDLAQYREMAVFTQFSSDLDETTKNQLAHGNVLMELLKQPLEHPLAMHEQVIILVAVGAKRLDMIPVKKVRDYKERLLEYFNTEQGEICQELEKSGDLSDQLKHKIIEAVDAFNDIENKKLKEEVEEIQKNNH
>NC_014387|1385734:1458193|1417871_1419032_+|WP_013280546.1|DBSCAN-SWA
MKSFWKKNVLIFLIAVMSIQLMGCGRGYTYRDKLSVEVRARIAATAYLFKNKFGAVLYNVDAYAPFVLIVKDSLYNEAECSYFYRGSKHTLWVNNDDGKIYTDDLVGYANKSLTDRFARKIGLPDGEKVELTYLPDYEIQTSTINDGSTYPANTHIDFFPSEYTEQDVDVYISEDNLKGEIRDIKIYSNRSCMDYDEIVTADKYHELFYGKDVTLYCTDGYVTYETEAGRTIIVTVYNEDSSIYADRVKLEYYDEYRYSYGYSVKDKKYVVSQKAFTDYSSKDFDVNLNGRGTDTVLKVRTRRDIKADLYVYGLNRLKVKCTYDHIYAQNSYPREQSYKVFNCKNGWKKLVDSRIREIKHRKSGIVPSCDQRVFSFNKDSDYVLDI
>NC_014387|1385734:1458193|1419172_1420072_+|WP_042256655.1|DBSCAN-SWA
MLILKAFGLIVFLMCVLYMLMIMPRVVNKPSSEPFTRVLYAHRGLHDNRSNAPENSMAAFRKAVEAGYGIECDVQLTRDGVPVIFHDFTLARIARYPDGCVPADAVPNPDGSLGVKGKVVDYTYEELLQFHLLDSDEKIPKFEEFLQMVNGTIPIIVELKIELKDLAVCRKVDELLEDYKGIYCIESFNPLGVMWYRKNRPQVFRGQLSDAFHKDKPEEFQGPLYFILTNLLFNFLTRPDFIAFNHKYANCLARRICRRVYGNVAAAWTIKSEEELAKARKHFDIFIFDSFVPQSGPKA
>NC_014387|1385734:1458193|1412644_1413247_+|WP_013280542.1|DBSCAN-SWA
MTDDGIEVPEELKKLENIDGLSISEGLYYCGSSKAYIKFLNTFFHTIDNRVQEIKESLERDDINTYTIKVHSLKSTSRIIGAGELSNFALSLEEAGERGDRKFISENNDKFLQLYISYRNKLAAFFENTIDTRKEISADMLSDAYSALREVVPSMDYDAVEMIIGGLREYKIPAADKEKIDRIASLLEQLKWDEIAQLLD
>NC_014387|1385734:1458193|1433722_1434148_+|WP_013280557.1|DBSCAN-SWA
MSDARVATFGLQVISVNGMFYDDRAEEIILPLDDGELAILAGHEEMILALNDGVIKIKKPGGEWIYGVVSLGSVQVANNRCIVIVNTVERPEDIDKRRAQEAYEFAMEHLQQKQSIKEFKKSQAGLARALTRLKAASKYSD
>NC_014387|1385734:1458193|1454502_1455195_+|WP_013280573.1|DBSCAN-SWA
MIYSTEVKNMCPVTQGVHHGAAPIPEEAKWVKSKEIKDISGYTHGIGWCAPQQGCCKLSLNVKEGIIQEALVETIGCSGMTHSAAMAAEILPGLTVLEALNTDLVCDAINTAMRELFLQIVYGRTQSAFSEDGLQIGAGLEDLGKGTRSMVGTTYGTLDKGPRYLELTDGYITDVALDENDEIIGYKYVNFGKMMDFIKAGDDANTAMEKAKGQYGRVADAVRCIDPRHE
>NC_014387|1385734:1458193|1425416_1427936_+|WP_042256658.1|DBSCAN-SWA
MDVQEIDLINELNIYTGLDSFSEDALEKELAQCKGLGANVEKLRSLGFNALQLAEIRKGLESDKVDVNKYLDSSLSWTDMEEMRLEMVQGIDMSEYRAKGFDNQQLYQIRTGISDGVDVSVYAKKIYLADQMRELRRGLSPKDGVPIIFFQDPAFDSLQMREIRRGLQVGIDISTYAMLDIPHMKMRAARLSAQDGLVFTEAEIRKYTASILEQMHQAHLDNVNISSYVKRLFDAEQLEQIRLALKKELPIDNYMTADMRGEAIKEIRLGLEEGVDVGKYADVAYNWKQMHEMRLGLEHQIDITPYCKPLYQADQMRELRLGIEAGLDISKFSSMMYTAKDMYRIRNKILSGELQSTVSEDSLEGSVFDRTGGVSDQTILLSSMLENRDQYLYVSEDKMKCWIMLPVRRDGISYTEDAIMTFLFKTKIRSGIDRKSIKQALLNPEPKEKYLIAQGKEVIDGADGHFEYFFDYEKNNEVKVLEDGSIDFSDVENIQQVKVGDKLAVYHKATKGIDGFTVYGELVKAKNGKEVPILKGDGFMIMSDRVTYVAKYAGAISVEEGNVYIKKVMILPEVKITDKKIDYDGVVFIRGDVHAGSEIRATGDIIIGGHMESSDIESKCNVIIAGGATCPTKGSIVAGGDVTAKFFDGVTIKGHNISSNYFINCKIEAKGMLKTFGRQGVIYGGTAYSLEGIESAEIGNVSGARTTITLGANTALLAEYSNLQKQISREAENLKNLIIQRDKLQELGSGNPQIMQLKIKVNAAIAIKQQAIKNLADKKQKLDSDVEKGEKAMAVVTEQIFAGTIIIIEGLALKITEDRKTIDKIVFRTDPKKEKILVF
>NC_014387|1385734:1458193|1435801_1438267_+|WP_013280560.1|DBSCAN-SWA
MTKEEFWGLSNNRILFLDGATGTNLMKAGMPAGVCPENWILEHQDVMINLQSNYAKAGADIIYAPTFTGNRIKLADYGLGDRIEEINSSLVKLTKKAAPGVLVAGDITMTGRQLRPIGDLDFEELVDVYKQQIKILEAAGCDILVVETMMSLQECRAALIAAKEVTDLAVMVTLTFEADGRTLYGSDAASSAITLEALGACAIGANCSTGPDKMAAIISDMAAVTSIPIIAKPNAGLPSVDENGNTEYDMDCDTFVKEMELLVSAGASIIGGCCGTTPDYIKGLKDRYGNVKPNDIRDGEGNPVPRKICGRRYLASERMSLSFGLDENFMIVGERINPTGKKKLQEQLREGNLDMVCDFAANQEKEGASILDINVGMSGIDEKEMMLKVMEEVMSITDLPLCIDTSSAEVMEAALRLYPGRALMNSISLEKGKAEKFLPLAKKYGAMFILLPLAEALPKDSQEKIDNINTIYEMATKLGMNKEDIVVDGLVATVGADPNAAINTLDTIGYCHENSYATICGLSNISFGLPQRSNVNTAFLTMAIARGLTMAIANPSQEMLVNAAFASDLLRKKEGADVRYITRMERYADQNSANSAAQNVSSSKAVLENDNILDIIKKDVLTGNKRGIVKDTEKAVKEGNSPRQILDEILMPAINEVGDLFDKGKYFLPQLIAGAEAMKLSIGYLEPLLKEGADSGEKLPSIVIATVHGDIHDIGKNLVALMLKNYGFNVIDLGKDVPREEIIKAARKYDAKIIALSALMTTTMKEMKNVVDLAHAENLDAKIIIGGAVVTQDYADEIGADGYSSDAADAVRVVKNILGIE
>NC_014387|1385734:1458193|1438281_1439910_+|WP_013280561.1|DBSCAN-SWA
MTGAEVIVRCLEKENTKVIFGYSGVAIDPFWNKILDSKIKRVLVRTEQNAAHLASGYARISGGVGVCAVTSGPGATNLITGIATAYADSIPLVAITGQVNSDMIGSDVFQEADITGAVESFVKYSYLVRDVNDLPKIIKEAFYIASTGRRGPVLIDIPFDIQNAEYKDKFAYPESISMRSYKPTVKGNMAQIKKVIKEVEKAKRPIICVGGGVHLSQATMEIRKFAELNSVPVVSTMMGIGVMPSDHPLFFGMVGNNGQPFANRAMNESDLLLMVGARVADRAVNRPDLITENKVMVHIDVDPAEIGKNVGPTIPLVGDIKNIFQDFLEQDEHADDHSDWLATLNKYKNEMASERVPRDDDYVEPKDFMTKLSAAVNDDAIYVADVGQNQMWSCAYYKVRNGRFLTSGGMGTMGYSIPAAMGAKLAAPDKQVLAVIGDGAFQMSMMELATMRQYGINIKIIVMKNGFLGMVREHQHYAYDDNYSMVELKGDPDLSLIAAAYDMEYMKVTGDDSIENKLKEFFSDDNAAIMEVRVDPMELVKY
>NC_014387|1385734:1458193|1439936_1440419_+|WP_013280562.1|DBSCAN-SWA
MRRIYSVLVENRAGVLSKVAGLFSRRNFNIDSLVVGETADKGISAMTIVSSGDERTIEQIEKQLNKKIDVIKVKTFKESMSINRELMLIKVKYNRDNRRDIMENCEIMNAQIVDMSKNLMMIQICDTSERIELFIEMLKSVSIVEIARTGTVALTKCKEQ
>NC_014387|1385734:1458193|1393572_1394472_+|WP_042256641.1|DBSCAN-SWA
MSRIIKEGYTSEDRKELEFIKETNLKYFKNQEELLGGDIILLEKQGDSSVRQEIDYLIESFNDGGWEYVESIFDKNIELCGYSDVIRDEISDFDIMKDNIIVRVLNYELHKNELEDRVYRKIGDFVLSVNGLIFSNSKITSFFKISADFLKAWGITEDEVIEIGLENTRRLFPPRVYGVEYALKIKTITQGDGDYMNNSQNIRLGNLGEDTFVAYGTQNGATSFFYPGVKEKIAEMLGGEDYYVVFTSTEDFHVHKCSQNDAASLEKRLIDMNKYFPLGEMLTEKIYKYSVDTGELTEV
>NC_014387|1385734:1458193|1402732_1404112_+|WP_013280534.1|DBSCAN-SWA
MSEEMKIPYKIYLSEDEIPRQWYNVRADMKNKPAPLLNPATLKPMTFDDLRPVFCDELIKQELDDTTPYIDIPDEVMDFYRMYRPAPLVRAYFLEKALGTPAKIYYKFEGNNTSGSHKLNSAIVQAYYAKKQGLKGVTTETGAGQWGTALSMASAYFGIDCKVYMVKVSYEQKPFRREVMRTYGASVTPSPSMDTEIGRKINAEHPGTTGSLGCAISEAVEVATKTEGYRYVLGSVLNQVLLHQTVIGLEAKAALDKYGVKPDIIIGCAGGGSNLGGLISPFMGEKLRGEADYRIIAVEPASCPSLTRGKFAYDFCDTGMVCPLAKMYTLGSNFIPSANHAGGLRYHGMSPILSQLYDDGLMEARSVEQTSVFEAAQQFARVEGILPAPESSHAIRAAIDEALKCKETGEEKTILFGLTGTGYFDMVAYQKFNDGVMMDYIPTDAELQKSFDTLPKINL
>NC_014387|1385734:1458193|1404845_1405265_+|WP_013280536.1|DBSCAN-SWA
MKDCNCGYCVGGEPLAKFGIKICDLEVSQLILFKEQSHPGRCIVAYKDHVSEIVDISDADRNAFFADVNRAAKAIHKAFNPDKVNYGAYGDTGCHLHMHLVPKYKDEFEWGGVFEMNPQKVFLSDSEYAEMIEKIKAAL
>NC_014387|1385734:1458193|1409971_1411702_+|WP_013280540.1|DBSCAN-SWA
MSLLDDKVNTVCVQDTDSYKALLNGGWNKRRLINKDSICKDNRNRNVVIKEYEVSEFGTYRVEVSILAGSKGFFDLTLFAGRRNMIARNIDIKASSKYHKVFYQAVFPYIPALTAERLNDKKIYISVAGIDEADADGALKVKITKEDVPVIWVAGDSTLTDQNAGIPYYPYASCAGWAQTISRYIRNAAVCNLSHSGMTSNCFRDDGHYDICREYMKKGDLFIIQFGHNDQKRRNLAAFGGYADNLKRYVNEVRKKGAEPVICSPISRIPLKLSEEEKRHLGMPMHYSLLQAHADAAKEVARNLNVRFVDLHKFSMDRWILFGDKAKDYFMPGDITHTNEYGAVMIADFFMSEVRDMIDEEMIENTAFSPDLDVKEIPKEIPGPGIFDIEPPYLDIKDNPYYEGIRKAFRYALLDPCVMYLHPDDCMPRGQLLMVMFNAFRMAGIRPYKKKFPDVQVDEWISGYVQALIENDLIDYRTYSSEKRDGTESETIYYFRPDDPLTYEELSQFLVLKLEHDKKECYTKRACELGFIDIDLNDKDKEISRAEVYTVLTRYMDKVKLADESLPSDAEVHPVH
>NC_014387|1385734:1458193|1405437_1407078_+|WP_013280537.1|DBSCAN-SWA
MANIINYIKWRGDLEFEKVPFNKVDNLGLTMLIYNDFSGIVPGKDEYGRISIREAADKYFQTHSLEGLDKYAFDWVLYYMGKYKRFGNLYLSDYVDVNDTDRNMVFTAFTVHLPDGSHFVAYRGTTMEIDDWRLDFQISFEEIEAQRAAARYLQYVMSKYAGDIYVGGHSKGGNLAVYASMNSSSEVRNRIKKIYSFDGPGFCPELLEKDKFNEIKERIVHIVPAFCVVGMLFELQVPHEIVASSASKIAQHSGMTWKIEGNHFVHRRFLTDESTVYNNAIDDWIGNATMEQRRAFTRDIFDAMKAGGAVNINEISEGGFHDFGTILLSAANSESKTKIVVGKFFGSLWRSFEKIKILDAVKSLQGIIDLFLIFVGIIFLTIPQAVYSVLGGAIALVVAIWSAVMLVKAGVRDENPFIKRGRMIFHIIIMWFMVFIMSNLERIPKWTNLLMAIVFFSLAFASVRYIIKYKTTISGKAKFWMMLLAVVNVYIGIIAIVMPDRFGITKSVTLGSYLIIIGFIRLIIQLLEQMQNPKSDGRFYEDEEEK
>NC_014387|1385734:1458193|1428780_1428996_+|WP_013280552.1|DBSCAN-SWA
MDLTALGAAIAVFTGIGAGIGIGVATAKATDAVARQPEANGKIMTLLITGCALAEATAIYGFIVAIMILFT
>NC_014387|1385734:1458193|1401651_1402536_+|WP_013280533.1|protease|DBSCAN-SWA
MEKKRFGFGKILVIIVLLVAAFLVGSSMYVVHQNEYVAVRRFGKIIAIASEPGLHFKTPFIEDTQSISGKIIIYDIPASDVITKDKKSMITDTYVLWRVSDPLKYIQTLNAVSARADERIEASVYNATKNAISSMSQDEVIEARGETLTKLITEEANSDMAGYGISIIQAQIKALDLPDDNKQAVYERMISERNNIAASYTAQGAAEAQKIHNETDKQVAIVKAQAQKSAAVLEAEGEAAYMETLSKAYDTEEKAEFYSYIRGLDTLKESLKGEKTIILDKNSELAQILYGNFN
>NC_014387|1385734:1458193|1389432_1389795_-|WP_052301803.1|DBSCAN-SWA
MKPVLDTKRLKEMREAKGWSKNRLAEEAGILQSAYTRYESGERSPSASVIRVLSLVLGTSVEYLTNKIDDKNPLDYIIKDRDKRLRFIVEKYSDLSEEQKDRVYLYVKKMLSSTSNKNKE
>NC_014387|1385734:1458193|1400177_1400591_+|WP_167531152.1|protease|DBSCAN-SWA
MLANDIKNRLIQPYFATVRDGTVSIITRNDILPTFFYALMMIVMKPVAEELFFRKAIISFGSKKRVFVLTLVSLILCAVTRAHGVLGIAEWILMAIPVTIAYVATRNIYISVMAHVAFEFYDNIYSIVYAVGRIMNR
>NC_014387|1385734:1458193|1456564_1458193_+|WP_013280575.1|transposase|DBSCAN-SWA
MRLNKILQGDYTVSSLYHQIKLPLDIEISIPSDDPVRLLSAFVEEMNLSDLYKTYDRIRKGQASPRQMLKIVIYAAMNRIYSSRDIESACKRDINFMYLLDGAPAPDHSTIARFISMHLSQCAKQIMAQVGTILLELGEISGENIFIDGTKIESVANKYTFVWKKAVSKNMIKLTEKICVFCAGCEELYGIKVVYNDQISLHTLKRLRKKLYKLKEDEGIEFVHGIGKRKTQLQRSLEALEEYIEKLKEYNHKLYVCGTRNSYSKTDTDATFMRMKEDAMLNGQLKPAYNLQHGVDSEYVTWLDVFPAPTDTITLIPFLKDMESHLTFKYKNIVADAGYESEENYIFIESNEQAAYIKPQNYELSKTRKFRNDISRRENMDYDPESDCYTCRNGQQLPAVSKRTQKSATGYQREVTIYECSSCNNCPYKKDCIKGNNCKTAFEDRNKKLSVSRKMEEKRAECLERITSDYGTQLRMNRSIQAEGSFANVKEDMNFRRYLYRGKENVLTQSILLAIGYDINKLHHKIADERTGTHLFELKKVS
>NC_014387|1385734:1458193|1400700_1401639_+|WP_013280532.1|protease|DBSCAN-SWA
MLGKRGNAPKAKANPKLIIVIVIAVLALLCVGESFYSVREQEQAVLTMFGKVLRVDTAGLYFKIPFIQDVHTIDMTTHGVGIGYYIKDGQNITVDDEGVMITSDFNFVDIDFYLEYKVSDPVAFYYNSSNPEVIMKNMALACIRNTVVNYTVDDVITTAKGQIQAEVKEKLQNELTNSNIGMMVVNLSVQDAEPPTEEIVQAFKSVETAKQGKDTAVNNAKKYQSEELPKAEADADKIVQDAEAYKQARIAEAEGQVARFNEMYEQYKLQPYITKKRLFYETMEEVLPDLKVIITDGNTQQMLPLDNFNGND
>NC_014387|1385734:1458193|1411855_1412617_+|WP_042256653.1|DBSCAN-SWA
MAFGSNKILVIGEKETFIIKVLLGKLKDAGITALFSKADVNDINEEWGDSGLIIYYLEAGERMDGDVATFLRDKLSDNNKQLALIGDAANTKEIIDSFPPHIIYKTFSRPIDYNAFISDVGLYFNMVAEGEMKKSILIVDDDPNYMGLVREWIKDTYKVSMANSGLRAIKWLGSNKVDLILLDYEMPVTDGPQVLEMLRSDDETKGIPVIFLTGKDDKESVMSVLALKPEGYILKTSGKAEIVNTISKFFVNR
>NC_014387|1385734:1458193|1398096_1399905_+|WP_042256648.1|DBSCAN-SWA
MEYIVVVLFAAAVFAAVILYLAFNQEQRERWLGFTFGIASVGGIAIYGTAHAHEATNLVAAIFETVVDVGRMFAGINNVSAFEKLVGADSKWMILFWGVHFLAYYSLASAIIMTVAKGMLKKIRTFFLHINDVELIYGITDNSLSYGRNIADKDHTSIVYVGTSTNGKESQISQMGGLLFSDSQALNPDAKFLQRLSVKRGKSKFRLCALSGNIDDNLEYAAKILRALEKAKVRPEQTEVILYGYEEHNGDMLQAVGDKYGYGTVRVFEKAELLARLLMQKYPICNAVTFDENARATCDTNVLLIGFGRKGQELLEKIVINGQFEGSNFKVKVFDKNGRGTDGFFRARFSSLLDNYDISFENHDGRSRELAVYLEENIDKLKYIAVAVGDDRTGREIAMNILEFMRGRGASLPVYQCCNDCVAKYELNSLVERYSIFDANILYNGMMDDLAKKLNHYYMNNSASAKKNWADCNYFDRMSSRASADYQAALLNRLGLCNGQELPAEILENLAKSEHLRWNAFYYASGYKKMDIETFKKRARNAQTSGNKRVSKDAEGKRHVCLVTWDELDEISDIENSIMGKDIDYKQKDRDNVLVIKGLLEK
>NC_014387|1385734:1458193|1448813_1450004_+|WP_013280569.1|DBSCAN-SWA
MNKDKVFEFLKKNTMIIVLLIVLGFFSWQTSGAILLPMNVSNLISQNAYVFILATGMLLCILTGGNIDLSVGSVVCFVGAVGAILMVNLNVPFWVAIIVMVIIGTAIGAFQGFWIAFVRIPPFIVTLAGMLAFRGLSNVVLNGLTVSIKEQTTFVNLFGGGADCYIRDFFGGESLNLTCLFGGILGVIAILSLNIYSRKKKIDSGYEVEALWAFCSKIILISAAILVFAYKLAQHKGIPTVLIWVLIVVIIYGYITSNTTTGRYFYAVGGNEKATKLSGIDTNKVYFLAYMNMGFLAALAGMVTIARLTSAQPTYGQNYEMDAIGSCFIGGASAYGGIGTVPGVIVGAVLMGVINLGMSLMGVDANMQKVVKGVVLLAAVIFDVVSKRGGKMIVKN
>NC_014387|1385734:1458193|1407121_1407997_-|WP_013280538.1|DBSCAN-SWA
MQEFKPVKEGKVREIYDVGENLIMVATDRISAFDVILKNKVSTKGAVLTQMSKFWFDYTKDVVKNHMVSVDTNDMPEFFRTPDFTGNSMLCKKLRMIPVECIVRGYITGSGWKSYQENGTVCGIKLPEGLQECDKLPEPIYTPSTKAEIGDHDENIDFERSIEVLEKEFPGHGEYYATKIRDYTIALYKKCADYALTRGIIIADTKFEFGVDENGEVVLADEMLTPDSSRFWPVEGYEPGHDQPSFDKQFVRNYLKAHPECDYNLPQDVIDKTIDKYHEAYKLLTGKELNA
>NC_014387|1385734:1458193|1434687_1435755_+|WP_013280559.1|DBSCAN-SWA
MKENRFLYAARFIACLAVITIHTRFPGKFGQVIDALARFAVPYFFAISGRFLLDASDNSIAFIRMRTGKALLKLLKITGIVYIIHLIFSLVVNIFNQMSVSEWLSSKFNFAELTNFVLYNSGRFIYDGSYTFDHLWYLFALIYVYGLIYIFAGVLIKWYKGLIGILLFFLYLGMLLQTYYPIRPFGINICTWFVMRNWLFVGIPFVLIGILFSDHIREIKATLSPKELEKWQVSTGYKAIAGLVFGIVLTIAEIGIYGNKEVHFGSLFIVISILFMSECRIPSGNYIWRIGKRASSNIYYYHVLIIAVIDIMAQKGIIPSLSMGIKPLMIMAICVILFYFVPVYFEKWLKMSSSR
>NC_014387|1385734:1458193|1443088_1444684_+|WP_013280565.1|DBSCAN-SWA
MYRVMLADDEGIVIDSTKFIIEKEFGNTCQVEFAKSGRKMIELAETFRPDIAIVDIHMPGINGIDAIREMQRFSSNTVFIVMSAYDKFDYAKEAIKLGVLEYITKPMDKTKVISVLKKAMEQIDSDREKRSNELLIKEKLETVEPIIENGLIYDILLQEHFEEDIDNYRTILGIEESYGYMMAIVCGDSQEGNHMTNAIGSSVKISGKYQEIREGVKNFFDCKIGNVMANKIAVLIPQKEPQMELGLRSELIDRAREMARYLRKKTDISFRVGIGGVKPLKELGDSYKEALNALIATTGSVAHADDLTINCDYEDGYPKALEKPLFEAVGKGDLNETRVIAEKYADWMCQKAADGDLMSMRLKVLEFSLYAEHLAYQNGGQTYRYSSRNNYLPEIMALETPMEIREWFISKVMAACSDVISKRQERSGNIIKTAKDYIDAHFDKDISLDDVSKVVNISPYYFSKIFKEESGLNFIEYLTNIRIEKAKNLLENSNLSVKEICISCGYSDPNYFSRSFKKNVGVTPTEYKDRF
>NC_014387|1385734:1458193|1394545_1395802_-|WP_013280528.1|DBSCAN-SWA
MFLFYIIVGLLIYLFYLIFRYFQVKANAFSKDEVIKAAGRQAKKLEYVDPEITCDFCGCKIDTRKYKVCPHCGGPYDKDIEWTSRHEVEEAFVERETLHLISKRQQKAAEESGKILARIKRSIFIIAILNLAAITVAIIYLNNARNSRYMGKTELNDTKYENYTEASYNIVGDGVLFDDGRVTITLEKFYVSDRVRDNEIDGYKYGNVKAAIHVINRLNSDILVTINSNSINGNSQSSYYISTYDYFKRNSDSVIYEKIYEMPYQSVSEIIFSRVSISNDDFTYNEAAETPICIRTDTDFSYTLPVKQDANLIFTSDKADVYSIYTEEDYNPRYLLYVVNKTDKDYMIKGTEVKIAGDEHGLYCFSESQVPAGYTFISNIHSYDAEEDISKKDCSLSIFFSCEEDPRYDFSTGYISLK
>NC_014387|1385734:1458193|1415762_1417793_+|WP_081441805.1|DBSCAN-SWA
MLAADSLKRDIQNTCLKSDEKGSTISFSEDPCIEKECFVICYGSDELKISASDDLGFIYGIYYISKVFLGVHEFWFWNEQKFIQRTGYEIPEGYRYASKPYAVRFRGWFINDEVLFDGWKKDKDDNRPWEMAFETLLRLGGNMTIPGTDFNAHIYKKLASDYGLWITHHHAEPLGARMFARAYPELEASYDKYPELFENLWREAIDDQKDCKVIWNLGFRGQGDRPFWADDPAYDSDEKRGALMSRLIRRQYDLVKEMDSNAVCCSNLYGETMELYQKGLLDIPEDVIFIWADNGFGKMVSRRQGRHNPRVYALPEKGAEGMHGIYYHASFYDLQAAAQMTMLPNSPEFVVKELMDVYDKKADDFWIINCSNVKPHAYMLDLIARMWKKPFGNIDAEGDADISLYVNAHLSDYCREYYGEEEDTLASIMELYRKWSSYCPFYGPNEDDHAGEQFTNHGTRVLVTGLITNYAKKNPGSTPAATEWLWFSDKETLREQLLDYREIIEPAQRGYEEYLVKCRQVLGSLSEYTRQVLEDTLIWQIEYHYYSYLGALHAIRAIDSIISSQQPADTDYLDAFYEAGLSAKAFKNGYDKMRSHEHGVFEGFFDNDCEADIRQSYYVMKGLMSFTRFHGDGPHFYKWQRMFQDGAGGNKVHLILRVKKHLTDEELYNLMEQARK
>NC_014387|1385734:1458193|1445992_1447072_+|WP_013280567.1|DBSCAN-SWA
MKKKLFSVMLAAAMAASLLVGCGSQAPASSSGGGNGKVGVAMPTKDLQRWNQDGANMEQQLKAAGYDVDLQYASNDIATQVSQIENMISSGAKVLVIASIDGDSLGTVLAQAKEAGIKVIAYDRLIMNSDAVSYYATFDNYMVGTKQGEYIKQQLDLDNAAGPFNLEIFTGDPGDNNARFFYGGAIDVLKPYIDNGKLVVKSGQVDFDNVATANWSTENAQSRMDAIISANYADGTKLDAVLCSNDSTALGVTNSLEANYTGDWPIITGQDCDIANVKNMIAGKQSMSIFKDTRDLAKKTVEMVDAIMKGTEAPVNDTETYNNGTGVIPSYLCEPVFADVSNYKELLIDSGYYTEDQLK
>NC_014387|1385734:1458193|1408113_1409754_-|WP_013280539.1|DBSCAN-SWA
MISANNVTLRVGKKALFEEVNIKFTPGNCYGIIGANGAGKSTFLKILSGQIETTNGDVVISDGERLSFLEQDHFKYDDNVVLDTVIAGNARLFEIKNEKDAIYAKEDFTDEDGIRASELEAEFAEMNGWEAESDAESLLNGLGIDTEYHYKLMKELDGAQKVKVLLARALFGNPDILLLDEPTNHLDLDAIAWLEEFLINFENTVIVVSHDRYFLNKVCTYIADIDYGKIQLYAGNYDFWYESSQLMIRQMKEANKKKEEQIKELKEFIARFSANASKSKQATSRKKALEKIELDTIKPSSRKYPYIDFRPDREIGNEVLTVDGISKTINGEKVLDNVSFVVQRDDKIAFVGGNELAKTTLFQILTGEIEPDEGTYKWGVTTSQAYFPKDNTKEFDNDYTITEWLTGYSEIKDATYVRGFLGRMLFAGEDGVKKVKVLSGGEKVRCLLSKMMISGANCLIFDEPTNHLDMESISALNDGMIKFPGVELFACRDHQVVQTTANRIMEILPDGSLIDKRSTYDEYLENDEMARKRTVYNTATDEEEDD
>NC_014387|1385734:1458193|1431346_1432318_+|WP_013280555.1|DBSCAN-SWA
MANIKEIRDRINSVNDTRKITNAMYLISSTKLRKAKKMLDETEPFFFATQAMISRVVRHLPEGVENVFLESRSEIPEQDRRRGYIVFTDDKGLAGAYNHNVIKLAEEHILNDGDKWKLFVIGEVGRYHFLSKNMDVEESFMFTSQNPTLHRARKIAAEILDYYTRREIDEFYCIYTTVHSNVCETRFEKLLPLDIITNIRKEKPAIGTMLEEFLMEPSPSAILDNIVPNYVTGYIYGALVEAFCSVQSSRMMAMDSANKNAAKMLDALQRTYNRQRQAMITQEITEVASGAKALKRAKLAKMQKSKKKQMHGQDAKMIDETRR
>NC_014387|1385734:1458193|1452857_1454288_+|WP_013280572.1|DBSCAN-SWA
MNSKLTIEEIVLINNLLYCENLGGPRGTFLHPSQQSKTIGDYVRGVLRKSEDIEDDTEYSTGVTGAEYKEILQAVKANEHLCEIIIQEVHYEGANVGGGRSAFLIDPVYNEAIVAFKGTQSDAEWIDNVSGLYTVPTAFQENALNWYRSLDLDGYDAITVTGHSKGGNKAKYITIMDDSVDNCFSFDGQGFSDEFIRKYSAEIVRNREKIINIIAESDFVNILLNDVGPKQFYLGTNFGRLGFAENHCANAILFFDDKGDMYLWKAKAQDKKMADLDKMLNSFIRTCRMSTKENIANMLGNVIVSAKAGDTEGLIATFTDERYKDSAASLAAYILRYKEEKPQMVASVREILGQNGFNTGMLGIIDFITNHEFLLEMIGKNPNAMIRLLKMNHAPEPAIVFLSSHFGLFSFIVLVSEKMHMLKDINLEGEDIDPEDEVITIGQKRRFYVSKRTVGIIAICIIATIVIIGMLVAIIM
>NC_014387|1385734:1458193|1432328_1433720_+|WP_013280556.1|DBSCAN-SWA
MSNGRILQVMGPVVDVKFDDGELPYITDAMEVYVEDQKRVMEVSQHIGEDVVRCIMLSPSEGLCKDMVVYPTGSPISVPVGEQVLGRLFNVLGDAIDNKGEVKCEEKWQIHREPPKLVDQSPVVEVLETGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIQELIQNIATEHGGYSIFTGVGERSREGNDLWSEMTESGVINKTALVFGQMNEPPGARMRVAETGLTMAEYFRDVKHQDVLLFIDNIFRFVQAGSEVSSLLGRMPSAVGYQPTLSTDLGALQERIASTRLGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRKIVEQGIYPAVDPLESSSRILEEDVVGKVHYETAMKVQEILQKYKELQDIIAILGMEELSDEDKLTVYRARKVQRFLSQPFHVAEQFTGIPGKFVPLAETIKGFKAIIDGEMDIYPEAAFFNVGTIDEVIEKAKQIEA
>NC_014387|1385734:1458193|1434164_1434683_+|WP_026662676.1|DBSCAN-SWA
MFSNRAHFYMIIIAVCSIFLAGCGNKASQELTDYKASMTEFYDKLSSLDNSINNIDTSSETAKIELLGYLDEMNEAYKVMAATAIPEEFSGITDIAAEAADYMQMANESYHQAYDGIFDEDSEMLASQYYERANSRVNVMLQVLHGEIPEGDGVIVTTQEAGQFSTIGATAE
>NC_014387|1385734:1458193|1389156_1389321_+|WP_167531151.1|DBSCAN-SWA
MMTKVEQLFYEEAAIKIAKNLLRSGIDVNVIAHDTNLPLDKVLELRDDITTEKE
>NC_014387|1385734:1458193|1414250_1415591_+|WP_013280544.1|DBSCAN-SWA
MKLNTKRTILIGFAFMSICAFWQFYDNEIPKILKYSFNLGETLTGVVMALDNVLALFLLPVFGTVSDGTETRFGKRMPYIVVGTILSTILLTILITVARPSGSLALFVGVLLLLLISMGIYRSPAVSLMPDLTPAPCRSSANAVINLMGTIGGIYILVMIKVLLKEADDPARTNYIPLMLSLVLFMLISIAVVFFAIKENRIKEEIHKEGGLHSLGDTFDDEKDAECLKNKELFEEGSVTKKMPQEVKRSLIFLLASVFLWFTAYNAVTTAFSRFVGEVWDLHDNAYATCLLVATIAATLSYVPIALVSSKIGRKKTILIGISIMAASYVITGLYPHFSPSINIFFALVGIGWAAINVNSYPMVVEMSKAGDIGKFTGTYYTFSMAAQVFTPIFSGFLLEHVSYRTLFPYAFIFSALAFCTMLMVKHGDVKPPKKERIIENFDVDD

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013280040.1|1385734_1386853_-|transposase	IS110 family transposase	NA	NA	NA	NA
WP_143754269.1|1387076_1388102_+	hypothetical protein	NA	NA	NA	NA
WP_167531151.1|1389156_1389321_+	hypothetical protein	NA	NA	NA	NA
WP_052301803.1|1389432_1389795_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013280526.1|1389925_1391863_+	AAA family ATPase	G3MAX6	Bacillus_virus	3.3e-42	36.9
WP_013280040.1|1392351_1393470_-|transposase	IS110 family transposase	NA	NA	NA	NA
WP_042256641.1|1393572_1394472_+	hypothetical protein	NA	NA	NA	NA
WP_013280528.1|1394545_1395802_-	hypothetical protein	NA	NA	NA	NA
WP_042256645.1|1395856_1397890_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.7e-50	28.3
WP_042256648.1|1398096_1399905_+	hypothetical protein	NA	NA	NA	NA
WP_167531152.1|1400177_1400591_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013280532.1|1400700_1401639_+|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_013280533.1|1401651_1402536_+|protease	protease modulator HflC	NA	NA	NA	NA
WP_013280534.1|1402732_1404112_+	TrpB-like pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_143754270.1|1404062_1404761_+	bifunctional phosphoserine phosphatase/homoserine phosphotransferase ThrH	NA	NA	NA	NA
WP_013280536.1|1404845_1405265_+	HIT family protein	NA	NA	NA	NA
WP_013280537.1|1405437_1407078_+	DUF2974 domain-containing protein	NA	NA	NA	NA
WP_013280538.1|1407121_1407997_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	1.4e-40	34.4
WP_013280539.1|1408113_1409754_-	ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	8.4e-55	26.7
WP_013280540.1|1409971_1411702_+	carbohydrate esterase 12 Est12A	NA	NA	NA	NA
WP_042256653.1|1411855_1412617_+	response regulator	NA	NA	NA	NA
WP_013280542.1|1412644_1413247_+	Hpt domain-containing protein	NA	NA	NA	NA
WP_013280543.1|1413287_1414151_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.3e-09	24.4
WP_013280544.1|1414250_1415591_+	MFS transporter	NA	NA	NA	NA
WP_081441805.1|1415762_1417793_+	glycosyl hydrolase 115 family protein	NA	NA	NA	NA
WP_013280546.1|1417871_1419032_+	hypothetical protein	NA	NA	NA	NA
WP_042256655.1|1419172_1420072_+	glycerophosphodiester phosphodiesterase	M1HZ90	Acanthocystis_turfacea_Chlorella_virus	9.5e-08	32.0
WP_013280549.1|1423420_1425223_+	cache domain-containing protein	NA	NA	NA	NA
WP_042256658.1|1425416_1427936_+	DUF342 domain-containing protein	NA	NA	NA	NA
WP_042256660.1|1428050_1428740_+	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_013280552.1|1428780_1428996_+	ATP synthase F0 subunit C	NA	NA	NA	NA
WP_013280553.1|1429023_1429500_+	ATP synthase F0 subunit B	NA	NA	NA	NA
WP_013280554.1|1429489_1431304_+	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_013280555.1|1431346_1432318_+	ATP synthase F1 subunit gamma	NA	NA	NA	NA
WP_013280556.1|1432328_1433720_+	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_013280557.1|1433722_1434148_+	ATP synthase F1 subunit epsilon	NA	NA	NA	NA
WP_026662676.1|1434164_1434683_+	hypothetical protein	NA	NA	NA	NA
WP_013280559.1|1434687_1435755_+	acyltransferase family protein	NA	NA	NA	NA
WP_013280560.1|1435801_1438267_+	homocysteine S-methyltransferase family protein	NA	NA	NA	NA
WP_013280561.1|1438281_1439910_+	biosynthetic-type acetolactate synthase large subunit	E5EQ70	Micromonas_sp._RCC1109_virus	2.7e-53	28.6
WP_013280562.1|1439936_1440419_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_042256664.1|1440528_1441617_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_167531153.1|1441609_1443085_+	histidine kinase	NA	NA	NA	NA
WP_013280565.1|1443088_1444684_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013280566.1|1444698_1445748_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_013280567.1|1445992_1447072_+	sugar-binding protein	NA	NA	NA	NA
WP_013280568.1|1447267_1448821_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.3e-12	26.2
WP_013280569.1|1448813_1450004_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_013280570.1|1450223_1452152_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_013280571.1|1452182_1452842_+	hypothetical protein	NA	NA	NA	NA
WP_013280572.1|1452857_1454288_+	DUF2974 domain-containing protein	NA	NA	NA	NA
WP_013280573.1|1454502_1455195_+	nitrogen-fixing protein NifU	NA	NA	NA	NA
WP_013280574.1|1455217_1456237_+	GGGtGRT protein	NA	NA	NA	NA
WP_013280575.1|1456564_1458193_+|transposase	IS1182 family transposase	A0A146ICT8	Staphylococcus_phage	3.9e-52	29.7

2. NC_014389

CRISPR-Cas detection and classification

Crispr_ID: NC_014389_1

• CRISPR_ID: NC_014389_1
• CRISPR_location: 336109-336644
• CRISPR_type: TypeV-A
• Repeat_type: NA
• Spacer_info: 8 spacers
• Cas_protein_info: c2c10_CAS-V-U3,cas12a

Consensus repeat of NC_014389_1

Consensus_repeat	Method
TTTTTAAGGTTCTAAAAC	CRT
ACCTAATTACTAGGTAATTTTTAAGGTTCTAAAAC	PILER-CR

spacers of NC_014389_1

>1.1|336127|49|NC_014389|CRT
GCCATGCATTTGGTAATCCTCACGAATCGCACCTAACAAGCAGGTATTA
>1.2|336194|48|NC_014389|CRT
ACAAAAAAGAATGCCAGATGTCAAGCACCTACCTAATTACTAGGTAAT
>1.3|336260|43|NC_014389|CRT
AACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAA
>1.4|336321|47|NC_014389|CRT
GCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTAT
>1.5|336386|49|NC_014389|CRT
AGTCCTTGAATGGCTAATCAACTTGCCACAACCTAATTACTAGGTAATT
>1.6|336453|43|NC_014389|CRT
AACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAA
>1.7|336514|47|NC_014389|CRT
GCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTAT
>1.8|336579|48|NC_014389|CRT
TCATTGCGATCTCATCTCCTTTCTGCGACGACCTAACAAGTAGGTATT
>1.9|336215|30|NC_014389|PILER-CR
ACAAAAAAGAATGCCAGATGTCAAGCACCT
>1.10|336284|25|NC_014389|PILER-CR
AACAACAATTGAAAGGAGAAACGTA

CRISPR arrays and Neighbor proteins around NC_014389_1

CRISPR arrays

The CRISPR arrays of NC_014389_1

>merge|NC_014389|1|336109-336644|CRT,PILER-CR
TTTCTATGGTTCTAAAACGCCATGCATTTGGTAATCCTCACGAATCGCACCTAACAAGCAGGTATTATTTTAAAGGTTCTAAAACACAAAAAAGAATGCCAGATGTCAAGCACCTACCTAATTACTAGGTAATTTTTTAAGGTTCTAAAACAACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAATTTTTAAGGTTCTAAAACGCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTATTTTTTAAGGTTCTAAGACAGTCCTTGAATGGCTAATCAACTTGCCACAACCTAATTACTAGGTAATTTTTTTAAGGTTATAAAACAACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAATTTTTAAGGTTCTAAAACGCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTATTTTTTAAGGTTCTAAAACTCATTGCGATCTCATCTCCTTTCTGCGACGACCTAACAAGTAGGTATTATTTTAAGGTTCTAAAAC

>NC_014389|1|1|336109-336644|CRT
TTTCTATGGTTCTAAAAC	GCCATGCATTTGGTAATCCTCACGAATCGCACCTAACAAGCAGGTATTA
TTTTAAAGGTTCTAAAAC	ACAAAAAAGAATGCCAGATGTCAAGCACCTACCTAATTACTAGGTAAT
TTTTTAAGGTTCTAAAAC	AACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAA
TTTTTAAGGTTCTAAAAC	GCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTAT
TTTTTAAGGTTCTAAGAC	AGTCCTTGAATGGCTAATCAACTTGCCACAACCTAATTACTAGGTAATT
TTTTTAAGGTTATAAAAC	AACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAA
TTTTTAAGGTTCTAAAAC	GCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTAT
TTTTTAAGGTTCTAAAAC	TCATTGCGATCTCATCTCCTTTCTGCGACGACCTAACAAGTAGGTATT
ATTTTAAGGTTCTAAAAC

>NC_014389|1|1|336176-336320|PILER-CR
TTTTAAAGGTTCTAAAACACAAAAAAGAATGCCAGATGT	CAAGCACCTACCTAATTACTAGGTAATTTT
TTAAGGTTCTAAAACAACAACAATTGAAAGGAGAAACGT	ACACCTAATTACTAGGTAATTTTTA
AGGTTCTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_014389.1|WP_013282982.1|325383_327063_-|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl|CDD|223989
NC_014389.1|WP_013282995.1|342548_343022_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282993.1|342043_342256_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282988.1|332417_333575_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282998.1|343632_344187_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282984.1|328321_329644_-|transposase	c2c10_CAS-V-U3	-	gnl|CDD|366606
NC_014389.1|WP_013282989.1|333777_335112_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282983.1|327052_328204_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282986.1|330138_331092_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282990.1|335074_335758_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282999.1|344155_345064_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NC_014389.1|WP_013282992.1|340618_341509_+|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282996.1|343055_343241_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282987.1|331352_332255_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282994.1|342275_342536_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282997.1|343401_343620_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_042258606.1|331143_331356_-|hypothetical-protein	unknown	unknown	unknown
NC_014389.1|WP_013282985.1|329647_330076_-|IS200/IS605-family-transposase	unknown	unknown	gnl|CDD|376616
NC_014389.1|WP_013283000.1|345077_345545_-|hypothetical-protein	unknown	unknown	gnl|CDD|380188
NC_014389.1|WP_013282991.1|336668_340394_-|type-V-CRISPR-associated-protein-Cas12a/Cpf1	cas12a	cas12a_cpf1_CAS-V-A	gnl|CDD|275131

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_014389.1|WP_013282991.1|336668_340394_-|type-V-CRISPR-associated-protein-Cas12a/Cpf1	cas12a	cas12a_cpf1_CAS-V-A	3.3e-262	867.9	55.7
NC_014389.1|WP_013282984.1|328321_329644_-|transposase	c2c10_CAS-V-U3	-	3.1e-15	50.6	5.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_014389.1|WP_013282982.1|325383_327063_-|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	8.44324e-21
NC_014389.1|WP_013283000.1|345077_345545_-|hypothetical-protein	gnl|CDD|380188	NF033183, colliding_TM, low-complexity tail membrane protein. Members of this family appear typically as an unusual gene pair with members of PF11998 (DUF3493). Strangely, members tend to have tail-to-tail overlapping regions, where the tail region from this protein is long, low-complexity, and typically rich in Asp, Glu, Asn, Gln, Ser, and Thr. These gene pairs occur broadly in Cyanobacteria. The function of this pair of convergently-transcribed overlapping proteins is unknown. The low-complexity region was trimmed from the seed alignment to build this HMM.	0.00955782
NC_014389.1|WP_013282984.1|328321_329644_-|transposase	gnl|CDD|366606	pfam01385, OrfB_IS605, Probable transposase. This family includes IS891, IS1136 and IS1341. DUF1225, pfam06774, has now been merged into this family.	1.37118e-06
NC_014389.1|WP_013282985.1|329647_330076_-|IS200/IS605-family-transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.82893e-46
NC_014389.1|WP_013282991.1|336668_340394_-|type-V-CRISPR-associated-protein-Cas12a/Cpf1	gnl|CDD|275131	TIGR04330, conserved_hypothetical_protein, CRISPR-associated protein Cpf1, subtype PREFRAN. This family is the long protein of a novel CRISPR subtype, PREFRAN, which is most common in Prevotella and Francisella, although widely distributed. The PREFRAN type has Cas1, Cas2, and Cas4, but lacks the helicase Cas3 and endonuclease Cas3-HD.	0
NC_014389.1|WP_013282999.1|344155_345064_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	8.73264e-14

Protein sequences

>NC_014389.1|WP_013282990.1|335074_335758_-|hypothetical-protein
MPKYHDHLGNEFASKEDMCRYYGINSTTFFNRLKAGMTLEEALTSPNLYSCTDHKGIFYKSKSEMVNTYGLKYSLFTHRLRKGWTLEETLEISPEIILLRGKWPSFSLNGEDYYTYKCPTCNNQFVFTPAECRQHYLRHKYSGEINETLYTKTPIRKLETVTDHNNNEYSSLRAMAKKYCIAVSTLKARIRRGWSLEKALTTPPDKTCIRAKRTLNAQNKIQGSSGK
>NC_014389.1|WP_013282989.1|333777_335112_-|hypothetical-protein
MLKIKFKDHLGNEYETRAEMAREYGLKPTTLEARLKRMNIEKALVTPVKEHCKGECFDHLGNIYPSENAMCKYYGIHPATFRDRIKNGWPLEKALSQQNYSVKIKCRDHLGNEFESKEAMCRYHGVNAETFRDRIKHGYSLEDALCPKKIADTNIYIDHLGNKFRSVKEMCNKYGVEVKTYQWRLRQGRSIKEALSSENNSCQKLRDHKGKEFKSLNALCRYYNVEPTIVKRQLDKNIPIKEAIKHAKCVKEHCYKDHLGNIYPTLNKMCKAYGITVGIYESRISRGVSLEDALTRPKRSHKVHDHNGCEFASLHAMCEHYGLGLESYIRRRNLGWDLEDALLTPVIHKEHKRYKDYKEKEYNSLKDMANAYGIKANVLSCRLRSNWPLKDALLLPDIRQNKIVVAFKVEDERYYFYKCSFCHEEHIYTATEINIHHHKHTQMR
>NC_014389.1|WP_013282988.1|332417_333575_-|hypothetical-protein
MKCCDHLGNPFSSQAAMCKCYGINQSTFVTRIKCGYSLEYALTHPASPSNAASILCMDHLGNEYESFKKMCEAYGHNDNTVRCRLRKGWALDVALTTPLFKDMYIYKGEKYSLKRLAQIYGVPYTRLVQRIRYGFTLEEALTIQNGHDRHSVKVAADGKVLYGSLKQFLKETGISTAYFYRQRKKGIPLEQILSDYRSKEKRCAENRKIKTICETYSISYETIKKRLEHGLSLEEALAAKNPLFKSCKDPFGNHYDTFKAMCSAYGQSDNAVRNRIKDGMTLLEALTVKPFQYIVDDKVYKTIKEASDTYGTCYATTRIRLKEGYSLEEAILIPSHWKWQNLKEKFSFNGEKYYSYKCDACGVQYMFTKPEIRAHTLMHIKNKDI
>NC_014389.1|WP_013282987.1|331352_332255_-|hypothetical-protein
MPKCLDHLGTEYGSKKERARAYGLGNTTVDERLSAGWSLEEALTTPSNHGNKRRVGCKDHRGKSYPSFRAMARAYGLEKSTLKERLDRGWSLKDALITPPDKTRITFDEEKAKENGISKSTYKSRLRRGWDEDAALSIKVGDAPYEALKEGEYCTDHLGKVYRSYKKRAEAYGQKVDVVWHRLEYGWCLEKALTVKDGRRVFCTDHKENKYKSITEMCDTYGIKRDVYIKRIESGYTQEEALLIPTGKEFLCKHHGKAFEMDGIMYYYCECPICKEEHVFTEAEMRSHTLMHVKNKEVRL
>NC_014389.1|WP_042258606.1|331143_331356_-|hypothetical-protein
MTNTKVTVHLGNNYSSVKEMCKYYGIDASKMHIYPRREYSFEKALTIPKKKSLKNKAIDKCIAFLYRLRG
>NC_014389.1|WP_013282986.1|330138_331092_-|hypothetical-protein
MAAHYNLRSDTLQNRLKNNWPLKKALLTPAGCKSQCTDHLGQVYANQSEMCKAHHIAFCTYKKNIQNGMSLKDALTSKKDTTVFDHLGNSYPSQTAMCMAYGINQWTFLDRIERGDSLEDALTRPLKTYFCTDHLGKTYKSRSAMARAYGIDPDILSDRLNEQKWSLEKALTTPVGAPREELKVKDHLGNEYLSIKEMAKAYKIPLKCLEYRLRNKMPLEEALMLPVDHGNAGSKPCKDHLGNEFKSMVAMARYYGKSPKAISACIKSGGNLKKLLAEDRIAEYTDHLGNIFASKSAMLKHYQIAQGTFDNIGGAHS
>NC_014389.1|WP_013282985.1|329647_330076_-|IS200/IS605-family-transposase
MDKYSIFTINSDVTHGRGYVYCLQYHIVWCTKYRKKVIIGNIESDVKEHLYRTAEDLGIKILAMETMPDHIHMLIECKPQCRISDAIKVFKGNTARWLFLTHPEIKTKLWGGHLWNPSYFVATVSERTKEQVTNYISSQKEK
>NC_014389.1|WP_013282984.1|328321_329644_-|transposase
MKIYSTYSVKIKQYNHIFSETVTIYRDAVNFLMDVCLAEWDLVSVIKGNQAQMMHVESLCHKTKENSSPKYDFDSRFYKMPSYIRRAAISEAIGKVSSYKSNLANWKLNPNGKKPTLNNCGYVYPSLYRIGMYNLADDYSAQIKIYHNNTWNWLSINLRKSDMDYIYHRCNGRKMCAPTLQKRGKEWFLDFPFEEKATLTDTNSLVVGVDLGLNSACTCCIMDSKGTIYGRRFLRLPRETDRLNHAVNRIKKAQQYGNRKMPRLWAKAKGINDDIAVKTANFIIDTAVMYNADTIVFEHLDLAGKKRGSKKQKLHMWKAKYVQSMVTDKAHRLSMRISHICAWGTSRLAFDGSGRVLRGKDADMPTYSLCRFQNGKTYNCDLNASYNIAARYYIREIFKSCSVTDRLDIEAKVPQCSKRSTCTLADLISLNAVLDNILVA
>NC_014389.1|WP_013282983.1|327052_328204_-|hypothetical-protein
MENGWSLQDALMIKPVHKVFKDHFGRKFETATDMCRYHGVSYSLYLNRLKSGKSLEEALNPHNKEKYIDHLGNVFNTQKEMCAFHGVSENTYYQRLRAGKTIEEALCKAAIYYKKDSDGKIFCRTKKEKQTLKREWFDHLGNKFSTLDEMCAFHGVERHAFTRDIKKCVSLKEALTPKVSVKVRCTDHLGNEFESITEMCKHHGITLSQYESRKRSDWPLERILSKGDYARRKTCTDHLGNVFESEIKMCQHWGVSDKTYRHRIIYDGWSLEKALTTKDIYTCTDHLGNVYKSKVEMAEHWGQKKGVIKDRLKLGWGIREALIIPNNTSKVYSTSGKKVLFEIDGISYYAFKCPCCNNEYAFTKEEIRSHYANHFEKGDMNEH
>NC_014389.1|WP_013282982.1|325383_327063_-|DEAD/DEAH-box-helicase-family-protein
MSTDILEAVRNRTKEDLKNKLSLFNRCAVPRCTGFGKTWLLSEIAQEYDTVLYLYPAEIIKKTAMHAIDETWEIEDEDESEAEEKKAIYDELGYELDYHNIRFMTYTKLARMDKKQIKELPLYSLIIMDEAHRLGGELTKTRALWLMYYQKNSHIIGATATPERMDAFDVIAEFFRGICVFQYTLHDAIQDGIIKMPIYIYCTYDIETSFKQAARLTGQDKNNIVVDEVLKSRLFEVSNVHNIPKIMKKTTDKYVSAKSYMKYIVFFPNIKKLLERYTKVEEWFKEAFPGYTVNTLVVTSENKTTQNNINNLNLKHHRKTIDLIACVDMLNMGYHVEDLTGIVMYRCTTSSQIYIQQFGRALSTGSKNRCVVFDIVDNLHRKSLFHLAPEGKRRIKRAHPTKKERAERLLDEIKHELTKKEQILMRKFIEDELEAEDQVAFDALWKKVNEISEEDIYAVDHLATYRELIAKTIAEVKYTRSKRAAEEYFRIQTSKCKRQIPNTVNELKKMKDLTPALKIFLDWQKIDEEDMLEYILEPGSVDKIDVKKIKQGIRDSMAY
>NC_014389.1|WP_013282991.1|336668_340394_-|type-V-CRISPR-associated-protein-Cas12a/Cpf1
MLLYENYTKRNQITKSLRLELRPQGKTLRNIKELNLLEQDKAIYALLERLKPVIDEGIKDIARDTLKNCELSFEKLYEHFLSGDKKAYAKESERLKKEIVKTLIKNLPEGIGKISEINSAKYLNGVLYDFIDKTHKDSEEKQNILSDILETKGYLALFSKFLTSRITTLEQSMPKRVIENFEIYAANIPKMQDALERGAVSFAIEYESICSVDYYNQILSQEDIDSYNRLISGIMDEDGAKEKGINQTISEKNIKIKSEHLEEKPFRILKQLHKQILEEREKAFTIDHIDSDEEVVQVTKEAFEQTKEQWENIKKINGFYAKDPGDITLFIVVGPNQTHVLSQLIYGEHDRIRLLLEEYEKNTLEVLPRRTKSEKARYDKFVNAVPKKVAKESHTFDGLQKMTGDDRLFILYRDELARNYMRIKEAYGTFERDILKSRRGIKGNRDVQESLVSFYDELTKFRSALRIINSGNDEKADPIFYNTFDGIFEKANRTYKAENLCRNYVTKSPADDARIMASCLGTPARLRTHWWNGEENFAINDVAMIRRGDEYYYFVLTPDVKPVDLKTKDETDAQIFVQRKGAKSFLGLPKALFKCILEPYFESPEHKNDKNCVIEEYVSKPLTIDRRAYDIFKNGTFKKTNIGIDGLTEEKFKDDCRYLIDVYKEFIAVYTRYSCFNMSGLKRADEYNDIGEFFSDVDTRLCTMEWIPVSFERINDMVDKKEGLLFLVRSMFLYNRPRKPYERTFIQLFSDSNMEHTSMLLNSRAMIQYRAASLPRRVTHKKGSILVALRDSNGEHIPMHIREAIYKMKNNFDISSEDFIMAKAYLAEHDVAIKKANEDIIRNRRYTEDKFFLSLSYTKNADISARTLDYINDKVEEDTQDSRMAVIVTRNLKDLTYVAVVDEKNNVLEEKSLNEIDGVNYRELLKERTKIKYHDKTRLWQYDVSSKGLKEAYVELAVTQISKLATKYNAVVVVESMSSTFKDKFSFLDEQIFKAFEARLCARMSDLSFNTIKEGEAGSISNPIQVSNNNGNSYQDGVIYFLNNAYTRTLCPDTGFVDVFDKTRLITMQSKRQFFAKMKDIRIDDGEMLFTFNLEEYPTKRLLDRKEWTVKIAGDGSYFDKDKGEYVYVNDIVREQIIPALLEDKAVFDGNMAEKFLDKTAISGKSVELIYKWFANALYGIITKKDGEKIYRSPITGTEIDVSKNTTYNFGKKFMFKQEYRGDGDFLDAFLNYMQAQDIAV
>NC_014389.1|WP_013282992.1|340618_341509_+|hypothetical-protein
MITKEDIVKALSEEGYEVRLVTKHKNHKTKEGITIRQNEEMTAPTLYMDEIPLDKYTDLKELISDIKDFLSRQSTRGDDLKKLAENIDDYNTVKDKLYIEIVSATDNEEFLSSMPHRKVLDFEVIFKLKLSDYAVASVSNALLEAWGVDIETLFNDAMASSEKNMPYGICHVSDVIPKPLTSSFINVPMYIVFRPDDENGAAAILYPEFQEFVGKQIGGFYILPSSIHECIMVPDAFYQLGGASEDVPGALKEMVSLVNKECVPKEDLLSDNAYHYDPNRKVLEFADEYFKNIKDA
>NC_014389.1|WP_013282993.1|342043_342256_-|hypothetical-protein
MKRLWKQGDRFKIDTDIDGVRACTQGTVEADQKKGDKKLLCTLDYVDGEGNVGVRVKIKDMYPVATDAAV
>NC_014389.1|WP_013282994.1|342275_342536_-|hypothetical-protein
MARRIEYPNPDIKCAWCGRDIGSDSRFYFKYKGKAFCSRYNKNSDLENICLKNYLVEEMGAEITEEEVDREPEYIMDEEVLYGLGA
>NC_014389.1|WP_013282995.1|342548_343022_-|hypothetical-protein
MEMKKAIRCIDQTYVEGNAKELVDKAYRYDDDFSDDAVQEIIDFATAQKEDCRTLIYLLEARQEEKEGKLLLGQIKNDILLYDSAEEFEYNDDTVEIWKESTTGQVLVHITGEDKQGPYHATNAYDFEEFMNRDMGSLESLIGETLFYGTVYDEEVA
>NC_014389.1|WP_013282996.1|343055_343241_-|hypothetical-protein
MDEVNFWDIVDLAPATNKMRRNFRARKSALDQIETKGTVDEKNKVPDEMWDEFWDDEEIGA
>NC_014389.1|WP_013282997.1|343401_343620_-|hypothetical-protein
MDQKKLFYNMCMDLWALGKELDKPRVDMTDEDWTRAIGKMDELTVKYKALGVREHDLISKLMMSILDYVENS
>NC_014389.1|WP_013282998.1|343632_344187_-|hypothetical-protein
MANYPVSISLEEYQTACNKTIRIQLWATIACATVGFLIFSVVIYNIAGEFPVMKIGERELSSLWFIAFFFSLFTIMAVLEILRNRKEGYSPNRLKEFYANRTRVSGIYVESGAGKHHTQKVYEDSGEIYQVYAPVPFKYYSLKPLVCRAFLVGNTALVYEIIKELDQYKSSEEYVMEMRRKGRE
>NC_014389.1|WP_013282999.1|344155_345064_-|CPBP-family-intramembrane-metalloprotease
MKRFHTDEYIWKDSIPIVLIAAFILMFIGQLIGIILTDIIFYAPLKNDTDGFYNVLLMYTSFIGIWMVINKWYEKHDPYAKKALTVKNVRLLSVQILSGLMIGTGLNTVCVMAATLRGDITLIYSSFQPLKLIAVFIAVFIQSSAEELLCRNFIYAKLRHSYKNPLVAIIANSIFFAALHLLNPGAGMMPIIYVFIAGIFFTLIVYYTGGIYCVMAAHAAWNYTQNIIFGLPNSGFTAQFSIFKLDAASARSSATYNTGFGVEGTWFAVILMLASCLAVFRIYSRKEKELSNNGKLSGQHQP
>NC_014389.1|WP_013283000.1|345077_345545_-|hypothetical-protein
MGECVDFEEYKKKRKKKLLFNGVKGRVNYANILPVAKLLVVISILDLILLALPDESLSELQRNISLGSYIPKDHAAVLLLLLIWALYGSYLKTIVSIKKKTRFYRRMDVTNLEVIAINLIGTLFEICLLFAASEGSAAAFVATVAFLMIMTRFWY

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014389_1	1.1|336127|49|NC_014389|CRT	336127-336175	49	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336127-336175	0	1.0
NC_014389_1	1.2|336194|48|NC_014389|CRT	336194-336241	48	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336194-336241	0	1.0
NC_014389_1	1.3|336260|43|NC_014389|CRT	336260-336302	43	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336260-336302	0	1.0
NC_014389_1	1.3|336260|43|NC_014389|CRT	336260-336302	43	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336453-336495	0	1.0
NC_014389_1	1.4|336321|47|NC_014389|CRT	336321-336367	47	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336321-336367	0	1.0
NC_014389_1	1.4|336321|47|NC_014389|CRT	336321-336367	47	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336514-336560	0	1.0
NC_014389_1	1.5|336386|49|NC_014389|CRT	336386-336434	49	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336386-336434	0	1.0
NC_014389_1	1.6|336453|43|NC_014389|CRT	336453-336495	43	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336260-336302	0	1.0
NC_014389_1	1.6|336453|43|NC_014389|CRT	336453-336495	43	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336453-336495	0	1.0
NC_014389_1	1.7|336514|47|NC_014389|CRT	336514-336560	47	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336321-336367	0	1.0
NC_014389_1	1.7|336514|47|NC_014389|CRT	336514-336560	47	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336514-336560	0	1.0
NC_014389_1	1.8|336579|48|NC_014389|CRT	336579-336626	48	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336579-336626	0	1.0
NC_014389_1	1.9|336215|30|NC_014389|PILER-CR	336215-336244	30	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336194-336223	0	1.0
NC_014389_1	1.10|336284|25|NC_014389|PILER-CR	336284-336308	25	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336260-336284	0	1.0
NC_014389_1	1.10|336284|25|NC_014389|PILER-CR	336284-336308	25	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	336453-336477	0	1.0
NC_014389_1	1.10|336284|25|NC_014389|PILER-CR	336284-336308	25	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	86189-86213	4	0.84
NC_014389_1	1.10|336284|25|NC_014389|PILER-CR	336284-336308	25	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	25946-25970	4	0.84

1. spacer 1.1|336127|49|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

gccatgcatttggtaatcctcacgaatcgcacctaacaagcaggtatta	CRISPR spacer
gccatgcatttggtaatcctcacgaatcgcacctaacaagcaggtatta	Protospacer
*************************************************

2. spacer 1.2|336194|48|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

acaaaaaagaatgccagatgtcaagcacctacctaattactaggtaat	CRISPR spacer
acaaaaaagaatgccagatgtcaagcacctacctaattactaggtaat	Protospacer
************************************************

3. spacer 1.3|336260|43|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

aacaacaattgaaaggagaaacgtacacctaattactaggtaa	CRISPR spacer
aacaacaattgaaaggagaaacgtacacctaattactaggtaa	Protospacer
*******************************************

4. spacer 1.3|336260|43|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

aacaacaattgaaaggagaaacgtacacctaattactaggtaa	CRISPR spacer
aacaacaattgaaaggagaaacgtacacctaattactaggtaa	Protospacer
*******************************************

5. spacer 1.4|336321|47|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	CRISPR spacer
gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	Protospacer
***********************************************

6. spacer 1.4|336321|47|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	CRISPR spacer
gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	Protospacer
***********************************************

7. spacer 1.5|336386|49|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

agtccttgaatggctaatcaacttgccacaacctaattactaggtaatt	CRISPR spacer
agtccttgaatggctaatcaacttgccacaacctaattactaggtaatt	Protospacer
*************************************************

8. spacer 1.6|336453|43|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

aacaacaattgaaaggagaaacgtacacctaattactaggtaa	CRISPR spacer
aacaacaattgaaaggagaaacgtacacctaattactaggtaa	Protospacer
*******************************************

9. spacer 1.6|336453|43|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

aacaacaattgaaaggagaaacgtacacctaattactaggtaa	CRISPR spacer
aacaacaattgaaaggagaaacgtacacctaattactaggtaa	Protospacer
*******************************************

10. spacer 1.7|336514|47|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	CRISPR spacer
gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	Protospacer
***********************************************

11. spacer 1.7|336514|47|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	CRISPR spacer
gcttccgaccaagaatgggtcgcctggaatacctaacaagtaggtat	Protospacer
***********************************************

12. spacer 1.8|336579|48|NC_014389|CRT matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

tcattgcgatctcatctcctttctgcgacgacctaacaagtaggtatt	CRISPR spacer
tcattgcgatctcatctcctttctgcgacgacctaacaagtaggtatt	Protospacer
************************************************

13. spacer 1.9|336215|30|NC_014389|PILER-CR matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

acaaaaaagaatgccagatgtcaagcacct	CRISPR spacer
acaaaaaagaatgccagatgtcaagcacct	Protospacer
******************************

14. spacer 1.10|336284|25|NC_014389|PILER-CR matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

aacaacaattgaaaggagaaacgta	CRISPR spacer
aacaacaattgaaaggagaaacgta	Protospacer
*************************

15. spacer 1.10|336284|25|NC_014389|PILER-CR matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 0, identity: 1.0

aacaacaattgaaaggagaaacgta	CRISPR spacer
aacaacaattgaaaggagaaacgta	Protospacer
*************************

16. spacer 1.10|336284|25|NC_014389|PILER-CR matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 4, identity: 0.84

aacaacaattgaaaggagaaacgta	CRISPR spacer
aacaactattgaaaggagaaatctt	Protospacer
****** **************. * 

17. spacer 1.10|336284|25|NC_014389|PILER-CR matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 4, identity: 0.84

aacaacaattgaaaggagaaacgta	CRISPR spacer
aacaactattgaaaggagaaatctt	Protospacer
****** **************. * 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	296861 : 345064	55	Bacteriophage(33.33%)	transposase,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_014389|296861:345064|DBSCAN-SWA
AATGGGTGTTGATAACACTAAGCCGGATATCAGAGAACTGTTAAACATCGTCATCTCTGATGTCTCAGGGCGCATAACTGAATATTGCGAGCATCCTGGCAGGGATTTTACAAGAACACGTAAGCTTCCTGCTGATATTCTCATGCATTTGATGCTGAATATGGCAGGCAATTCCTTAAATAAGGAAATATATGACCATTTTCCTGATAAGAAACAGCGTATGTCAGCTTCAGCATATGAACAGCAGCGAGAAAAACTTAAGCCTGATGCGTTTAAAGCCATGCTTAGTGTTTTAAACAACAGTTTCACAGATGCAAAAACTATGAACGGCCTGCGTGTTTATGGTATCGACGGTTCGGATTTCTGCACACCGCTTAATAAAGACAGTAAATGGTATATCCCCAATCATTATATTCGCAAAGACGGGCAAGAAGCCAAAGGCACATGCCTTCTGCACGGAAATTTCTTATACGACCTGCTTAACAAACAGTATATGGATGTCAATGAAACTCGCGATGAGCGTGAAGGCGCTGTTGGTCTTATTGACGGAATATCTGACACTGGTCATTCTCTTGTTATTATGGACAGAGGGTATTCTGGCTTTAACATGATTGAGCATTGCAACAGATATGGCGGTTATTACGTCATCAGACATCCTCTTACCAATACCATCAAAGAAATCAGTGAGCTTCCAGATGAATCCTGTGACAAATATATAGAAGTCAAAGTCTCTACAAACAGTCAGCAGTGGTGTGATATCTACGGATATCGTAAGCTTGGTGTCCGTAAGAATAAGAAAATTTCTAAGCTGTATTCGGATAATACTAAGGCTACGCAGTGGGACTTTGAGGTAAAATGCATTGTTAAGTTCCGTGTAGTCAAATTCAAAATAAACGATCCTGATACCGGTAAACAGGTTTGGGAAGTTCTTGTTACGAATCTGCCACGGGATAAATTTGACTTAAAAACCATGAAACGCATCTACTGGCTCAGATGGAATATCGAGACTTCGTTCAAGGAGCTGAAATATGCACTCGGAGCTATAAACTTCCACAGCAAGAAGGACAAGTTTATCCTTCAGGAGCTGTATGCGCACCTCATTATGTTTAATGCGACAGCGCGTGTGGCAGCGCACATTCCTGTCGAGTATTCCGAAAAAGGATATACCTATGCTGTAGATTTTAAGATGGTAGTCTATATATTTCGCAAGTATTTCAGGCCATTCAGCAAAGATCCACCTGAAGATATGTACGCTGACATGAAACAATATCGACACATGTTAAAGGACGGCAAACATAATATCAGGTTACTAAAACCAAAGTCAGCGGTTTATTTCACATATAGAGTTGCTTAAGCAGACAAATACGTCTGCTTATAAGTCGTGCAGAAAGTTTATCTTTTTGAGTAAAAGAAAAGTGCCGGACAGGATTTTATTCCTGTGAACCGACACTTTTAGTTTTTAATCTGTTTAACTTAATGAACCCCAGATGAATCCAATACCATTTTGAAATTAAAATTTCTTAACTTAATGGTATTGGGTTTGCTCTGGGCGTCTTATACAGCAAATTTGAACTTTGAAAGTGATCTTGTTTGGATCCTTGTTATGGTCTTTTTCTTGTATTCCTTAACAAATCCAAGGTCATATCCATATTTCTTGCAAACCTTCTGATATCTGTATGCAAGTGGGATAAGTCCCTCAATCTCCATTTCAGTAGCTTCCTGTTCCTTAACAGATGAAAATGTTTCTGTAAGATAATATGTAAGAAGGTCAATCAGCCTGTAAAACAGTTTGCCAATAACCATCTCATTAAACAAATCTTTATCTTCTCTATAAAGGTCAACGAGGTTTACTGTTTCGGGGATATACGTGGCGTATCCTTCCAGATCCCTAATCCAAGAACCATTTTCAGGTCTTACGTCTTCCAGCCCATTTATATGCTGGATTGTTACTCGAGATGAAAGTCCCAAAAGCTTAAGCTGCTTATCTGTTAATGGCAGCGGCTCTTTCTCATCCTGCTGGTACGAAATATCATCCCATGAAGGGATGTTTGCATATCTTGCGATCATATGCGTTGCTTCCTGATAGGACATCATCTTTACGTTCTGTACCAGTTTGATATTATCTCCGTGGTCACCGCATGCATAACAGGTGTATCTTCCATTTTTAATGAAACAACTACCATAATGCTGATCATTATGCGCCGGATTTGGACACAGGATGCTAAGGAGAGACCCCTGGCGTCTGTATTCAATTCCTAGCATTTCACAGCAGTCCTCGATAGGGACTTCCTTGATCTCCTCCTTCCATTCTGCGTATTCCATAAATCACATCTCCTTCATATAGTCGCGAATCTGATTCTTGCCAAAATCATTTTTGGCTTTATATCTTCTATCTTCAAAAATGCGTCCGCTTTTCACAGAGGTAAAATCAATACATGCGCGAGACATTCCTGCAGCTCCTTTAATGAGCTCCATCTTTTGTTTTTTCTCTTTAGTCATAAGTTTATCCCTCCTAATATCTGACATCAATTTTTCTTTAGATATTATGTAAAAAGATAAAATAAATATGTGCGCCGCTTTGCTACCCAGGTCTTGAAAGGCTTTCGCTTTTAAAATAAGGGATTTCCTTTCTTTTAAAATATATTTTTATAATTCTTGAATATATATATTTGCCAATCAGTAACCAAATTCCTGTGCCCAGAAGATCATGTCATCTTCTGTATAGTAGATCGCCATTCCTATGGTCTGGTATTCAGCATTCATGATATTATCCCTATGCGTTGGCGATTCCATCCATGCATTAAATACGGACTCTGCATTGAAATACTGTTTTGCAAGATTTTCTGCATACTGAACATCCGGATCTACTGTCCAAAATTCAGTACCATCAGGTCTTGTGTGCGACCAGCTCTCTGAAGCTTCCTTTGCTCTTACGCTGGCAGCAGATGTAAGGGCATCGCTCCATGATAATGCGGGCATTCCCTGCTCAGCTCTCTTATCATTTATAAGCTTTAAGACTTCCATACAGTTATTGTCAGATCCGGTTGTATCCCCGGGTGTATTATCCATGTATTCACTTTTAGCTTCGCTCTTATCTTCTCCTAGCGAGAAATATGTTGCTTCTGATGCATCCTGCGTATAATCTTCATTTGCACCATCTTCATTTGAGGCAAAACTGTCATCAACAAGTTCTTCTGTATTTACTAATATGTCATCCCCGCGTGCGTACTCTTTTTCATTCTCCTCTTTGGCCATTTCTGTTTTATATAAAGCTGCTTCATCTAGCTCTTTTATTTCGCCTGCGGCAGCAGTTATACTTCTTAATACCGCACCAACGATAACGGCGATTAACAGAAAGGCTATAATACGACCACGCCTGCCTTTCATAAAAATCATTCCTCCTTGTCTTCTTTGAGGCACGATTTTTATTATGGGAAAATTGAATATAAAAAAATACAGCTGCATCTGCAACTGTATTTTATACTATTTTACTCGTTCTTAAGTCGCTTTTCAGCGAACTTATAAACTTCTTCATTTCAAGTTTTGAACAGATGTGAACTACCACGCACCTAAAAGATACGTGGCTTCTAAGAGCCTTACGGTTCTATTTAAGAAGTGTGATTGCTTACGCAATCCTTATTCTTACAGGCGTGTCCACTTCGCCTCTACTGTATAGAGCCTCAAGGCTCACAACGCTACTTTTACGCAGAATATTAAGTGCTCCATTTACATCAGCATTCAGAGTTTTACCGGATGATGTTCTGTACTGTCCTCTGTAGATACGTTTGCCGCTGAACATATACTCCTTCGGATTGTCATTATTATAGACAGGGATCACATCCTTATCCCAGAATGATGCTTTAGAAGTATATGACTCTTCCTGTTTTATGAAAGTTATGCCATTCAGTTCGCAAAGATATTCAAGCTTGTCACGAAGCTTTCCGTACGGGATGTTTACAAAGGTCTGATTATTTCTTTTACCGATGTTGCTGTCGCGCTGAAATGTTTCGTTGTATCCAACGACAAGTGTGCCGATGTCATTAGAGATACAATAATCTATGACTTTACGTGCAGCTTTGTTCATGTAGTCATTTACTTTGTTGTTACGGTCACGGACAATGGCTTTCTGGCGGTTTGTGGCCTCTTTGCCAAAATGCTGTTTATCCTTGATGGACTGGAGACGTGCGTTTTCTTTGTTGAACCACTGGTTGATGGATTTAAGCCTTTTCCCGTCAATGATGAAAGACCTTCCCGTGTTTGATACTGCGGTCACGAGATTGTTTATCCCAAGGTCTAGTGCAAGTGAATTGTTTTTGTTTAAATTCCTTTGAGTGCATTCAACTTCATAAGTGTACTGGATCTCAAAGAACCTTGCCTTTGCTTTGGGGATGACGCGTATCTCTTTGATCTTTTTATCAATAAGCATGGGAGGTATGGTTATCTCAACAGCCTTATGTGTTTTCTTAAAGCTGTTAGAGAATGGGAGTATCAGCCTGTTGCCGTTATGTCTTACGAATCCTATGACAAGTGTGGTAAAGCCGTCCTTGGGAAGATAATGTGGCAGTTTGCAGTCTTTGAAAGAATACTTGCCCTGCTTTGCCAGCTTTAACAATCCAAAGAACGACTTGAAGCTGCCATCTACTTCCTTGAGTATCTGTTGTGCCATGTTGGAGTTCAGTGTCCTGTAGTTGGGGCTTGTTTTAAGAAGGGTGTAGTTCTTCTCATATTTAAGGAACTCGCCTTCAGTAAAGTAATACTGACGGACGTTATAGATAGCCTCATTAGTAAGGTTTTTGGCTGCGTGGCAAAGTTCCCTGACAGACTTGTAATCGTCCTTTGACAGATGCTTGACCTGCTGTTTTACAGTAAGATACATGCAGTGTTCTCCTTTCTGAAGACTCGGAAATGTTATCCTGTATGTATACTATATCACTTGTTTTACTGTTTCATTATATTATTAGTAAAATATATATTTACTTTTTCTAAACTGACGCCATTCATCCCACGGTCTGAAGACCGATGGGTTTTCTGGCTGATGTATTATAAAACAGGACTCTTTCCATCTTGCTTTCCAGAACTTCATTATAATTATTTGAAATTCTAATAACAGTTTCTATCAGCTTATCTGCAGCCTCGTGAAGCTCTCTGTCTTCCTTAGCCTTTACTACAAGATATTTGTCCAGCTCAGTTCTTTCTCGCTCCCTTTTGTTCTTATCCATGAATACCTATTTCATCCTCCTTACATGGCAAAAATCACTTTATTTGCCTTCTCTGCTACTGTCGCTGCATTGTCTTCAGCTAAAAGATTTTTATATCCATCTTCGCTGAACTGATATACGGGATATCCCAAAGAAACAAGTTCCCTGGTTCTTTTTTCGACATCTGCAGGAATCTCAACTTTCCTGATCCCGCCAATAAAGAAAACGATGTATTTCATGCGCTCAATACGCCATGAAGCCACATACTTGTCAAAGCTCTTTGTATCTGTAAAAGATACCTGATCCTGAAATGCAAATTTCATGATTGTTCTCCTTTCTTATAACCGACATTAATTTATTCAGCTATATAATGGTTTTTATAAAAAGAAATAACATTCTTGTGCGGAAAAATGAGCCTAAATATTTGTCTGATATAATACATAGTCAGGAGATTTATAAATGGATACGCAAAGACTTTTACAAAAGATAAATATTAAGGATGCGAACGGAATGGATACTAGGGATGATACCCTGCAGCTTATTTCTGATGCGATAGATAAGATGACTCCTCAGGATGTTATCGAGTATAAGGAACATTCTATTAATGCAGACCAGCTATTTGAAAAATATTATCCAAAGCTTTCGCCGATCCCAGCATCTGCGATACAGCAGATCATATCAAAAATTCCGGATATTATTGCAGATTACGAGAAGGCAGCAGATGAGCGGGGAGAATATTTATATCAGCTTTTGTTTGCGGGTATTGCTGCAGAGATATTTAACCAAAACGATAAATCCCCCGTATTTGATGGAGATGTAGATTCATTTTCAGTCATACCGGATGATTATACTGCCTGGAAGGAAAAGATAATAGCACTTCTTAAGGAATTTACGCAGAGTGCTAATGGAGCTATTTTATTAGAAATCACATTATTTCTTGGAATTATTCCAAATAAAAAGAGCTAGGGTTTATGAAACCCTGGCTCTTTTCTTTAAATAGTCCAAATAATTTTCAAATCCAACAAAAGTAGTTCCTTTGCAATACTGCTTTGCTATTCCTCGTCTTTGCGAGATCACAAGGATCTTACTAACAGCTTCTTTCTCCTTACCTCTTGGGGCAGAATACTTAAAAGTTGTAAGAAGTAAATAGCATTCTGCATTGGAAAGTTTCGCATCCGCTGTTTTAAGATCAAAGCGGTATCCGGTAACAATCTGCAAATCTCCCATTTTGCCACCTTTCTGCAGTTCAAAGTGTCTGCACCAAGCTTCCATGTACAAAGAGACGCTGTCCTGAATGAGCAATTCCCTGGCAGGTAACCAGAGTAAGAATTCTTCCATCAGTATTTACATCTGACTTCTGAGTGCTTTTATCAAGCGCCTTCTCTACATACGCATTATGCTGGCCTTTATCGAATGTAACAAACATGCTTGATTTCTCTGTAGCACTGTATGTTGAGAAGATCTGGTAAGTATAGGTATGATCCTTGGTTACTACCCATATATAATCTTCTATGTTAACATTTTTTAAAGTTCCAAACATTGTGCGATCTTTCATGTTATGTCCAAAAATAATGGTATTTTCATCTGAAAAATCACTATTGTTTGAGGCATTCATGAAGATTTCGCCATGAGATGATCTCTTCCCTTCAGCAGTATGCTTAAGAAAGTACTCGTTATCCTCTCCCTGATATACAGGATATGAGAGGTTTATGCTTGGGATATATATCCAAGCAACTGCATCAGTCTTTGTAAAATCAACATCTTTTACTGATGCAGGAACATCAATCACCTCTCTTTCACCTGCCTTTGCATCTAGTGAGATTTGGCTTACAGCAAGCTTAACTGAATTTGTGATGCCATAAGTTACCTGTCTTGCAGAAAAAATGCTGCCCTGCACTTCCTGCGCGTTTTTGACCGTTGTCTCTACCACCTGTGTGCCCATTGCCAAATACGCACGTAAAGCAAGTGCCAATACGACGCTTAAAGCGAAACATTTAATCATTCTTTTCATATTATTCTCCTTCTGTTTAACCAACATTAAATGATATTCGTAATATGGTTTGCGCAGAAAAAAATAAAATCTCTGAAAAGTCAATAGACTAGACGCTAATTTAAAATGAGGGTACGGGTACTGGCCTATTATGCTATTTAATTATGAAATCGTTGATATAGGTGGTTGTAGATATCAGGTAGGAGTTGGGGTTATTATCAATACCAAGACACAGGTTTCCTTTTTAAAGCCCGGCACTACTTATTTTGCTAATATTTGCATTGAAAATAATGAAGTTGTCGCCAATACAGGCCTTCGTGATGACGAAATTTTTTCTATCTAAGAATGGATTGATAAAACCGCATTGAGATCTGGGAAAGGCATCAAAAGTTCCCCTACCGTCACAAGAGCAGCTCCTAGAGCTTGCCAAAAATGCTGTAAAAGAATTAAACAGACTATCTAAAAAGAAAACATACAATGCATATGTACCAAGAAGAGAATTTGCCAAGATAATGGACGATGGGGGCTCAAAGAAGAAAAGCTGAGAGTGATGATCCCACAGCGGTAATTCAAAATTGGATGAGAAATAGAGACGTGATTAAATTTCTTGGACTTTTGGGAGGGAGTTCATAATCCGGATTTTAAACCCCTCGAATTCGAGGGGTTTAGAAATCAGGCAGATATGGTGGAACGTTTGCACATTCAGACATAGCTTTTGAGTTCGCATCATGGATTTCTCCAGAGTTTAAGTTATATATCATCAAGGATTGCCAGCGCTTAAAGGTTGATAAAAACAGTCGTCTTTCTCTAGGATGGAATTTACATAGGGAGATATCCGAGATATTTTTTGTAAACATCTCTATTATTCTTGCTTCTCAGGATTGTCTTCTATGAATTCCATGAAGAAATCAAACATTTTAATTTTGCGTTTTTTAGCCTCTGGGGTCAAACCATGACATGTTCGCAAAGGTTTGTCCTTGATGCTATCAAGATATGATTTTACTGGGTTTTCAAGAGCGCCTTTTTCCATAACATAGTTCTCCTTTCAACTATTTCTTTAGTTCCCTCATCTATAATCGCCTGCTCAAATGTATTTATCCAGTTTACGTTTGTTTACTGACTCAATTATATCACATGTATACCCATACCTAGTTTACAGAATCTGTATATGGCCAAGCAGAGCCTTCTCTTGCATCTCAGAAGTAATTCCTATGTATCTTTGTGTAGTCACTACGGAGCTGTGCTGTAAGAACTGCTGTGCAAGGACTATGTTGAAGTCATTGTTTTTATATATCTCCATTGTAAAGATTTTCGGGTATTTTATCCTAGTATTAGCCTCCACATTAAAATTCTTATATGGAACCATTGCAAATAAAGCGTCCTATTCCAGGTTTCTCATCAGGTTAATACGCCTTCATTTTATATGTTTCCGATATCGGTTTAACTTCAAAATTAACTCTTGGCTTTCTTTGGCCATTTCTTTTCTTCAAGAAGAATAATCGCTTCATCATATTCTTTATATGAAAGATTATCTTCTATCGCCAGTCGTTTAACCAGTTCTTTGGCTTCTTTGAGATCACACTTTTCTATGGCCGCCTTAAGAGTTATTTCACCGCACGAAATCTCGTGTCTCATGTATTCTATCTTTTCTACTGATACCATACGGTACCTCCTAGAACTTAGTTTGATGTTTGACTAGAAGCTGCTGCACCTGATACTTCTTCTGGCTGTGTTTCCTCAGTCTTTTCTTCGAAAGAAAGCTCGTTCGATGCTTCTTCCAAGGCTTCATCTAAGCTGTTTTCATCCTGTGATATTTCACCGGGTGCATCAGATGAATCATCCTTAAATATATCTCCCGCATATAAATTTACAAGATAATCCATTACTGCATCTGCCAATGCATCTCTTTCATAGGACTCAAACGAATTATCAGAAATAAAATCCTTAAGCGTATCGTATTCCGATGTTTGCGATGCCCAGTCTGTTGCCGCAAGACTATATGCATCTATATCATCAACCGAAATACTCTCTTTTTCGGCAATTGCCTTATAAATCAAATATAGCTTTGCATTCCTTTCAGCACAGTATGCAATGTAATCCTCTGTAGTTCCAACGTAGCCTTCTTTTTCCATTGTTGGAGACACGAGATCATATAATGTTACTTCTTCTTCACTTGTATCAGAATAATATTCTACAAGATCTGTAAGCTGCTTATAGAGAATATCATAATATTCGTTCTTAAGGTGTTCCTGTATATTATTTACCTTACAATTATTATAGAGAGTATTTGAGATTTCTGTCTTGAGTTCATTTTTGTATATATCTTTATTATCCCTGTTCAAGGCATCAATCAGATACTTTTTTAATGATTCAAGATCAGTAACACCGTCAATTCCTAATCCTCCAGCTATATCGTCTGTAATTTCCCCATATTCATACACGGTTACTACTTCAACCACATATGGGGTCTTTTCTCCTGAACTGTCGGTTGATTCAAATTCTTTAGTTTCCCCTTTTGAAAGTCCGATGACAGCTTCTTCGAGTTCTGCTGGTACTGAGTCATTCCCTAAAACAATTGTTGCTGTGAGTGTAGATGCCTCATCTATGCTCCCATCGGCATTTTTCTTAGTAAGACTAATATCAACAGTACTGTCGCTTGAAACCGCCTTATCGATGGGTACTACATAATTATAATCCTTAGCGATATGTTCCAGCTCTTCCTTTACATCGTCTTCTGTAGCTTCTTTTAATGTTGTTGTGATCTCCATGTTTCTGTAGTCATTTAAAAATACGTCGTTGACTGCAACTCTGTTTTCTGACGCCGTTCCGCATGCCGCAGTAGACACGATGACCCCTGCGATAAGTATACCTGTTAATGCATTTTTCGTTTTACGCCTTAAATTCATCTTCATTCTCTCCTTTAGTAAATAGCATGTAAAATTCCATGCACTACAAACCTGTCGTTATCGCCGGAACATGTTGATAATGTTACTATTGGAAGCCCACTGCTTAAATCAGAGTTCACATTCCATTTGCTTTTTGAGCCGCTAAGGCATTCATTAACAAACCGGTGATATTCATCCATTCCGTCGAAAAATCTATAGCATGGATCATCAGCGTGTATCACTCTGGCAGAAAAGATCTCGTATTGTCTCATATGGCCATCTGGCAGGTAAATATAAAAATACGGATCTTCCTTTGCAGCTTCAGGGTTATCTCTAATTTTTTTAAGCCCGCCAAACATTGAGTTATTCTTCATATTATGGCCATAAACCAAGGTATGCATGTCATTAAAACTTCTGTTGTTTGTATAATCCATAAAGATAGCTCCGGCGGAATTTGCAGTTCCCTGATATGTAGTCTTTAGGTATTTATCATTATCAGGGCCCTGAACAACCGGATAATTTATACTGCAAAAAGGCACGGTTATCCATGCCGTCACATCAGAATTTTCATTTATCAGCGAAAGAAAGTCTACCTTCTTCAAATTGCCTTCTGTTGCATCGTGCATCTTTTCGTCAAGAGAATCTTTTGCTCCTGGATTCTCCTGTGCAAGAACCTTTATATACGAGCCTATGTCACTTGTTTCTTTTGCGTAATCATCTGCCACTTGTTCATATTCGTTATCAGCTATTTCGTACTCTTTTTGGTAATGAATAAGAAACATAAGGGCGGCAATAAGCGAAATGGCGGGTATTAGGGCAATCAGCAACGCTTTGGCAATATTAGCCCGTTTTCCGTTATGCTGTGTATCCATAAAATACCTCCTGCGTATTTTACTTTTTCACAATATCATTCAATATTTCTTTAACATTTTTCTGCACATAAATAAAAAATGAGGCGCCTAAAAGACGCCTCAGAATTTTTTGCTATTAAGATATTTTCTTTCTTGTATAGAAAATGCCGATTCCAACAAGGCTGATAAATGAAATAGCCATGAGCATCATAAGAAGTCCGATTGGAGTCTGGTCTCCTGTTTTGGGAGCCTTGGCGCCCATAACCATTGCCTTTGCATCATACATGATGATTGTCTGTGCGCTACCATCTGCCGTAAACTGGATATCCTGTGCTTTTACATATCCTGCTGGGACAGTAATCTCTTTAAGGGTATATGTTGTCCCCTTTGTAAGTGTTGAGATTGTATATGCATTATTTGTGGTAGTAAACTCAGCAACTTTTGTATCACCATTGTAGATGGCAAGAACCGCCCCATTTACAGGTGTTGTTGTTCCTGTCTCATACTTTAAGATTGTAACAGTACCTGGAGTTTCAGTCTTTTTCTCAGTCTTCTCAGGCTCTTTGATTTTCTTGTCAACAAGTGTAACAGTCTTTGTTTCATCATCCTTTACTTCTATTGTTACGCTCTGCTTTGTAGCCTTCTCATATCCCTCTGGAACTACTGTTTCTTCTACAGAATATGTTCCGGGAAGAAGAGAGAGCTCCTTGTCCGCATCAGAAGATGTTTCAAAGATTATTTCTTCAATAGCATTTCCATTGAGAACTTTTCCTGTAACTTTAAGCTTAGCACCGGCAACCCTGTTATTTCCCTCGTCAACTTTCTTAATGATAAGCTTGTGTTTCTTGTAAGGATCTGTGAGGCTCATGCTCTTTGTTTTTCCGTTTTCTACGGTAAACTCTACATCTTTTATTTTCTCGTATCCCTCTGGTGCTGATACCTCAACAAGCTTATATTTCTCACCTACAACAAGGTTATCAATAGTATGGATGGCTGTTGTTGACTCCCACTTATCTACTTCTGTTCCTTTTGAGTCAACCACCTTAAGAACCGCTCCTGGAAGAGGTGTTTTTCCATCGTTACCGTATTTGATGATAGCGACACTTCCGTACTTGGCAAGAGGATCTACCATACTATAAACATGCTTGCTGGCATCAACGTCATCAGCTTTAACTGTGATAACGATATCTTCAGCTTTTGAATATCCGCTTGGAACCTTGGTCTCCTTGATCGTATATGTTCCTGGAAGAACCTCAAACTCTACCTTACCTGTAGAAGGAGTTGTCATTGTAAGAGTAACGTCTTTTCCAAGATAGTCTTTACCAGTAAGTTCAAGGACTGCTCCTGTAACAGGAGAAGCTGAAGTTGAATCGTCTACTTTGTTGACAATGATCTTGTGTTTTGAATAACCATCATTCATTTTTACAAGCTGATATGAACCTTCAGCCTTAAATGTTATTGCATCGGTAACGTCATAATTTGAAGGCGCTGCTGTTTCTGAAAGAGTGTAATTCTTCCCAAGTTCAAGACCCTTAACAACATGTGTATTTGTATCTGTCGTCCATGTATCAACTGTATTGCCAGCCTCATCCTTGAGAGCAAGTGTCGCTCCAGAAAGAAGGCCATTTGAAGCAAGATCAATCTTATTGATTCTTACACTTGCCTTTCCAGATACCATTACCTGCTGAGTAGAAGCATCCGGAATATAAGCAGTAAGGTCATTTGAAACCACAGTACCATTTACTGCAGTATAGTCCGTATATGTCTTTGATAGGATTTCTCCTGCTGCCGCAAGTGTCTTGGTTTCATCACTTGTATTAAGTCCTCCGAGAGAAAATCCCTCTGAAGGAAGCACTCCTGAAAGCACATTCCAGATAGCAAGCTGTGTTGCGTTATAGAATTCAGCATTGCTGTAACCCTTGCTATCCTGGATGCCTGCTCCGTCATTTGGGTATCCAAAGAACAGGATTGTGTTAAGCGCATTCTGCACATCTGAGTTGTAATTTGAAAGATTTCTCTCAACTACTCTTGTGCTATCAAGACCTGAAAGACGAGCTCCGACAGTATCAAGGTATGTACTCCAGCTGCTGCCATTTGAAACAGTACTAGCTGCGTAAAATCCCATCTGACCAGGGATATCAAGATTCCAGTTTACACAGTATGCTGCGAACTCCTTGTTCTTTCCCTCATCAGCAATGCGATAAGCATTAGCTGTGCCAAGGCCTGAAATATGATACATTGAATCGAGTCCTGCATTTACATAGGCTTGTGTTGTTGTCAGTCTGTGAAATACAGAATTTTCTGTTGCAGAGCTACCAATCCATGAGCTTGCAAGTCTTGCGTCATCGTCAGCTGCTCCTTTATACCATCTTCCTGTCCACTCTGAATCAGCACTAAGTGCAGCCTTTGTCTTTAAAGTAGTCAAGTTCTCCATATGGTAGAGCATCTTTGTCTGTGTCGCAATTGTATTCACACTTGTAAGATCAAGTGTTGTAAGTCCTGAGTTGTAAAAAGCCTCTGTAGCATCTGCTGTGTTTGCTGTAAATGTAAAGTTTGAAGGAAGAACTGTAAGCTTTGCATCTCCCTTGAACATCTGCTTGATCGTAGCGGGAAGCACGATTGCATCTGCTGATGTTATTGTCACAAGTTCCTTACATCCGCCAAACATTGAAGTGGCATTATCCACGATAGATACTCCGCTTCCAAGCTCGATTGATGTAACCTTCTTAAGGTTTGCAAATACGGAACCCTTAAGAGTGATTGTTTTACCAGTGCCTGGCACGATTTTAACCTTTGTGAACTGGTCAAGCTTTGAGGCAAAAGCTGTAGTAAGGTTTTCGCTAAGCTGTGCCGTTGTATTTTCGGACTTTAAACTGATAGTAAGAGTTTTTGTTCCTGCATCAATATCAAAGTCAAACTTTTCAAGTCCGGTTGAAACATCAGGAGTAAGAGATGTTCCAAGAAGCGCATTTACATTTGCGTTGTTACCATTTGTAGCAGAAAAAGATGTTGCGATATTCTGAGCTGTCTGAGAAGCGGAAGCTGAGCCGAACACAAATGGAGAGAAATGCTCAACATTCATTGTCACATTATCTTCGCTTATCTTTACATCAACTTTCTTTGTATTAGTGCCCTCGCTGTCATCCATATGATAAACAACAAGCTCATCTGCGGAAATATCAAGTGATTTTAATATTCCATTTAAAGTTATCTGTGCAGAATTATTTTCTGCTGGCTCCCATACAGATGCGCCATTATAAACAGCGATATCATATACAGCTGCAATATCAAACCCCGCATCTTTTTTCTGCATTACAGCCTCGATATTCTGATATGCAAAACGGTCAGGGGTAAGCTTTGTAACTGTAAGTTCAGAGCCTTCTGGCATCTGTGCATTTACGCTGATCTTAACAGCGCCTTCTGAAGCAGTAAGGCTGTCCGCCTTCTTAACCTCAGTTTTAGGTGTTTCTGCATTCTTAGCATCATCCTTTTTCTGCTCGGATGTTTCCTTTACAGCAGTCTCCTCCTTAACGGCATTCTTCTGGGAATCTGCCTTACCCTCGGCAGCCTCAGATGTTTCCGCCTTATCAGAAGCCTGTTCAGATGAAGATGCTACGGCTGCAGTCTCTGTTGATTCCATTACTCTATTAGCTGCATATGCTGTAGTGCTCATTCCTGATACAGAAAGCACAACTGCAGACGCAAGAGCAACAAATCTCAGGCTTTTACATTTCATAACATGTTCTCCTTTAGATCTGTATTTAATATAGTTACCTTCGAGCTTTCTGCGGCGAACAAAAAGCATCCCTCCTATTATGGATTAATCAGGCAAAATAAAAACCCGGGTGCAATTAAGCACTCGGGTCTATATTTAATTCATACTTCTTCTCCACAAAATCAAAATAATCTTACTAATCTGATCATTGTCTTGAGGACAAAAAGTCCTACAAGAATTGCTGCTGCCATCAAAAGGCAAAAACCAAGGTCTCCGGTCTCTGGCACTTCTATGTAATCACCAAGTACTTCGCCTTCTTCCTCTTCCTCAATAACCACGGGAGCTACAACCACCTCTTCTTCAACTACTTCTTCGTAGTATGTTTCAACTGTTTCGGGCTGATACTCGGGCTCTGGAGTTGGCTCAGGCTGAGGTACGGGAATAGGTTCGGGCTCGGGCTCAGGCACTGGTTCTGGCTCTGGTTCTGGAATAGGCTCCGGCTCGGGAGTCGGTTCCTCTGGTATTTCAGGCACCTCCGGCTCAGGATCTGCAGGAGTCTCGACAACAATCTCAAGATCATCATCAATCTCTGCGCCCTTTGCTTCACTTGAGAATGACATTGTCATTCCCATTGCCATTACTGTTACCATTGTCATTACCATAACTGCCATTTTCTTCATCATAGTTTCTCCTTCTGCTCTCTTTATATAAAAGAGGCCTCACATCTTTAATCTTTACAAATTATTTTCCTTACATTAGTTAACGACAGTGATGACAAAATAAAATTTGCCATCATTACCTTTTGCCACGCCGGCTCCAATACACGTAACTCCATCCTTTAACAGGACTTCATTATGACCTGGTGATTTCTTCCAGGCTGATACTGCGCGTTCTGATGAGGACTGTCCACGGGCAAGGTTTTCACCCAGCTTGGAATAAGTCTTATTCCAATTATTTCCGAAAGCGGTCTGCCATTTCTCGCCATTTGGGCGGGTATGACTGAAAACTCCGGAAGATGCCATTTCTTTTGCTCGAAGCTGAGCTTCTGCTTGAACAGCACTATCAACAGTAAGTGCCGGTAGTCCATTCTGAAGTCGGTATTCATTTACGCATCTTACAAGCGAAGCTGCAGATACATCTTTGGCGCCCGCATAGGGGAGTCTGCCTTCCTGAATACCATTGTTCCAATAGTGTTCAGCTAGTACTGATGGGGTATCGCCGACAGCTGCTACTACATCAGGGTTAGCATTTGCATAGTAGTCAGGATCAAATCTTGATCCATCCGGTAATGAAAAATCAGCATGCGCTGTGATCGCAATTGTGCTGCAGAGCAGTAAAAGCGCAATCAGATGCAGTAGTTTTTTCTTCATCTTGTTCTCCTTCCTGTAATAACTATCATTAAAATACATAAAGGATAATGGTTTTTATTAAATAAAATAAAAACGGTCTGCACAAAATATGCAAACCGTTCATGGCTTATTAAATTTTTATCTCTTTAAATCCCGAGAATAAGCGCTGCATGTCTATAAAAATATCATTAGCGCCACTATGACCTTTAACAGCTATATCCGCGAAATATGTAGAACGGGCTTCGCCAATAAATTTGACTCTTACCCCATCTTTGGTCACTTCACGGAGCTCCTTATTGATATCTTCCAGTACGTAGTCCCCAGCTTTTATATCTCTGACAGAAACCGTTTTAAGGTACTCTCCAAATCTGTTGTGAACTACTCCGACTTATAGAAGTCGGAGCTTCTAAAGACGGGCGGGAAATCCGCCATTTTTCTTATTTAAGAAGTTTGATATTTAAGTTTCCACCTAACAGGTTAGGCAATCCTTATTCTTATAGGCGTGTCCACGTCGCCTCTACCGTATAGGATGCTAAGATCCACAACGCTACTTTTACGCATTATATTTAATGCTCCGTTAACATCGGCATTAAATTTAAAACCATTGGCGGTTTTATACATTCCACGATGTATTCTACTACCACTGAACTGATACTCTTTTGGATTATCGTTATTGTAAACAGGAATACAGTCTTTATCCCAAAATGATGCCTTTGATGTATAGCTTTCTTCCTGTTCAACATAGGTAATACCATTAAGTTCACAAAGACATGACAATTTATCCCTTAATAAGCCATAAGGGATATTAACAAAGCTCTGATTATTCTGTTTGCCAATATGTGAATTCCTTTGAAACGTAACATTATAGCCGGCCACAAGTGTTCCGATATCGTTAGTAATACAATAATCTATCACCTTACGTGCAGCTTTACTCATATAGTCATTTACTTTATTGTTACGATTACGATTAATGGCTTTCTGACGATTTGTAGTCTTTTTGCCAAAATGCTGTTTGTCCTTAATAGACTGCAGACGAGCATTCTCTTTATTAAACCACTGATTTATGGATTTAAGCTTTCTTCCGTCAATGATGAACGATTTCCCAGTATTTGATACTGCGGTTACAAGATTATTTATACCAAAATCGAGAGCCAGTGCATTATTTTTATTGAGATTTCTTTGAATACACTCAGTTTCGTAAGTGTACTGGATTTCAAAGAACCTGGCATGTGCTTTTGGTATAATGCGTATCTCTTTAACCTTTTTATCAAGCAGGACCGGCGGTATTGTAATTTCAACCGGCTTGTGGGTTTTCTTAAAGCTGTTTGAAAACGGAAGTATCAGCTTGTTATCGTTAAGTCTCACAAAGCCTATAACCAGTGTGGCATATCCATCTTTTGAAAGATAATTTGGCAATTTGCAATCCTTAAAAGCGTATTTACCCTGTTTTGCAAGCTTAAGCAAGCCAAAGAATGACTTGAAACTGCCGTCTACTTCTTTGAGGATCTGCTGTGCCATATTAGAATTTAAGGCTTTATAATTAGGGCTATTCTTTAAGAGAACATAGTTTTTCTCATACTTTAGGAATTTACCCTCAGTAAAGTAATACTGTCTAACATTATAGATGGCTTCATTTGTAAGATTTTTCGCTGAATGACACAGTTCTCTTATTGAACAGTAATCATCTTTCGATAGATGTTTTACTTGCTGTTTAACAGTAAGATACATTCTATAATTTCCTTTCATAAGACTCAGATTACTCCTGTATATGCATTATATCTTATTTTTACTAAAAATACATGTTTGTAGTAAAAATATGTAAAAAAAAAGAATGGTAGAAAGCTACTATTCTCTTATAATGTTCTTGGTTTAACGCATTCATCCCCTACCTACGCTACGCTTAGAGGTAGGGGTTTTCTGCGAAATTTTTGATAAACTGCCAAAGTGTGCTTTTCATAGATCTTTTCAAGCTCTTCTTTTGTCACTTCATAAAACATATTACTCTCCAATCCTAGCCGCAAAGGCCTCTTTCTTTAATAGCATCTTCAAGCTCTTTGCAGATATACTTATAGTTTCCTGCATCAATGCTCTCTTCAAGAGCCTGCTCATACCAGAAATCCATATCTGTGGCCACCGTTCCATCCTTTCTTATAAGAGCATAGGCATCACCATTCGAGTAATAAGAATTACCCTCGCTATCGATAAGCTGAAGCGGCAGGATGCATTTTTCATCCAGATATCTCTTAGATATCGGTCTGTTTATCATCATTCCACCATTATCAAGCTGATAAGAATTATGAGCTCCACTGAATGTAAAGAACTTTTCCATCATCTTCGCGAGATTTTTATCTACTTTTATCGCTCTTACTGAGCTATTGTCATTTATATATGCCCTGATAAGCGATGCTGCGGCTTCCTCTTTATCAAAATGATGGCCCCAGAAGTTTTCACCCAGGCCAAATCCCTCTGCTCCATTTTCATAAAGTCTAAGGTTGTCAAATACAACAGTATCTTCGCCATTATCTTCAAGATTTACTCTATAGGCATCTGCTTCGATCCTGTATTCGTTGCCTTTTGCAAGGCATGTCATTATCTCCATGTTTTTCTCCTATTTTGTTTATCTACTCCGAGAATAAAATGAAAGGGGCACGCCTTTTAGCATGCCCTTTGCTCCATTTTATTTATCCTCGACCACGCGCCACCATCTTTTGAATGCTTCCTTGACTTCATCAGTGTCTTTAAAGCATGACGGAGACCAGAATGTCTGCTTATTTAAGTCAATGTTATCTCGTCCTTTGTATTTATCTCCATAATCGCCGTACGTCACATATAAAGATATATTTGACTTCTCAACTATGGATCTTACAACAGAACTTGTGACAAAACTTTCCTTATCTCCGCCACATGATGAACCTTCAAGAGCATCAATTGTTCGGCGCAGCCAGTGTGAGAATAAGCCATTATATATTGATTCAATATAAAACTCATCCCATCCTGTGATCTCCTGGTGCTCCATTAGAAATGGCCTTGCAGGAAGTTCCATAAGCCTCATCATTTCAAGATGCATGGATGTCTGATAATAATCATCACCACGCTCTTTATAAGACTTATAGAGTTCTTCGATAAGCTCGGCGCTCTTTTCGTTATTCTCAGCCTCTATGGATTTAAAAAGTCCATTCATTACTGAAATAAGTGCATCTTTGGTTTCAGAATTATTTAACATCGCACCTCCTTATGCTCTTGCAACAATCTCGTCCATCTGGAAGATACTGATAAAGTTTGTTACGTTATCTGAGTTGGTGTTGTTATCAACCCAGACAAAGTTCTCCCCAAGCTCTTTTCTGATCTCAGAAAGGGCTTCTTCTCCAAACTTTTCTTCATCATCCCTAAGACGTCTATTCCACTCAGTCTCATCGAAAGAGCCTCTTTTCATTGCTCTTTCTTTCCTTACTTCATCTGAGGCATAGATATAAAAGACTTTGCAGTTTTCTTTGCCGCAGGCATCGATATAAGCCTTGGCGCCTTCGCAGTCAACGATTGCTATATAGTCCTGGCTTTCAAAGTTCTGAACGCTGGTCCATGGGGTTCCGTAGTACCAGTCATCAGCTTTGCCCTGCACGAGAGTATGATAGCATCTCCATTCGAGCATTTCTCCGCTTGAAGCCATTCTCTTAAACAGCTCTTTTGTAATGAAATGGTAATCTTTGCCATTAACCTCTCCTACTCTCATAGGTCTTGTTGTACAGGTGATGATAGGAAGACATCTATCCTTGATATCGATTCCCTTTACAGGCTTACCATCTATGATCCTGTTTAGCGCACGGTCCTTACCGCTGGCACTCTTGCCAATAAGAATATAAATCATATGTCTCTCCTTTCTTTTCCGACATTAAACGTTATCAAGGAGTATTATGTTAAGTTCTGCAAAAAATAAAACACATTGGATTTGGATATAAAAATACCCTGACGAGCTTATCTCATCAGGGCCTTGTTTAAATATTGGAAATTTCTTTATTTTTATCCTCTATTTTACCAACAACGCCTCCCCATATCATAAAACCTCCTATGAGCATCATAAGAAAATTTCCAATGAATGCGTGTTTAGGCTGATGCTCCGACCATTCACCGTTATGCTTACTTACCTTGATAACATCTCCCTCGTTTGGGAGGTTATCCTCGAACCTTCTGTTAACAACAATCCTTGTTTGTTCCGGATGTTCTGTGGACAGCCCAAGTGTTTCTATGTCGCATACAGCGTCATAAGTAATCAACTTATCTATTCCGCCATCATTGCCGTTTCTTACAGTCTCTCTATTTTCTGAAATTTTGACAATTTTTACCACTTTTGCCTGATCTTCTTTTACAGAAGACTGCCTTGAAAATCCAATAAGACTTAATAAAAGAAGCAGTGCGCCGATAGCAAAGCATATGTATCTACTTGATTTACCGTGTAATTGTACATTCATAACCCACACCTCCCATTATAGCTGAGAAGCAGGAGCGTTTATCTGGATGCCATTAAGGCGCACATCGCCCTCAAGAGCAACAACGATGCAATTACGGCCATCGATCTTCCTTTGCTGAACAAGATTTGTGCGATCAGGCTTTATCTTGATCTCAACATCAGATGACTTTACCGCAAACTTATCAAGCTCAATAAGGTTACCCGTTTTGAACTCTGTATCGTCATTTCCGCCAGCTCTTTCGTAGATGTGTTCAAAGTCATCGAGCTTTTCTTCCTTAACGCCTGCAGATACTAAGATCTCCTTTATCTCTTCTTTATGGAGAGTCTTGATCTCACCGTTATACTGGGCGGTCTCTTCCATCTCCTTAAGGTTTTCGTGGAGAGTCTTGATTACCTCAAAATCTGCCTTATCGTCAGTTACCTCTGCAATGATGCTCTCGAAGATATGCTGCTGATCCACAGATGATGTAGGAGCGGGTATGCCAAGGAGCTTTTCGATAAGCTCGGGATGGCTGTCCTCTGGCTTCTTTGTAAAATACAGCATGCTGTGAAGATCTGTATCCCTGTCATTAAATGCAGGATAAAGGAAACCATGGACAGGAGCCTGGACAATCTGGACCTGTCTTGAAGAAACCATACGTCCGCTGTCGCTATCAAGAGTAAGGCCTGCCTTTGTTGAGTGCACAGGACAAATAGCAACAAGCATGAACTCATATGTTGTAGTCTCATCCTCAAGAATGGCTCCATCTGAAGCCTTCATTGGGACATCATATACGCCATGGCCTGCCACAATAAGGTAGTTTTCATCAAAAATATAGTTCTCGATGATAGTATCGAAAAGCTCGTCTCTCTTTTCTTCGCTCTTAAATACTTCTGTATAAGCTTCTGTCATGAAGCCTTCTGCTTTAATAGACGCTTCATTTGAGCCAAATTCAAGGTTAAGGAGCTTTTTATCAATTGTTCCTGAAAGAGCTGCCTTAAGGATATCTATGTACTTAAACTGCTCCTCATCTCCAAGTGAGGAATAGCTTTCTGTATTAGATATGAGTTTTTCCTTGTTCCCATTTACAAAACATGTACAAATACGGTCAATGCTAGGCATAAACTCTGTTGTTATCTTAAGGGTCTTTTTAAGTTCCATAACGTTTGACTTATTCATTTTTGGTCCATCTCCATTTCTCAAAATAAATGGCGGTCATACCAACCGCCATAAACCTTCGTTTACCTTCTGCTCATCGGATCCCATTTAAAATTTGGACATCCGTCTGGCACGCTGTTGCTATAATCATTTCTCAATGTACAGGAAGCTGTCCGGCATTCAGAGCATTTAAAGCCTCTGTGATAGACGTACCTTCTCTTACAGGCCAGTGAACAGAACGGATGCTTGGAATTCTTTGAATTGAAAGTGCGACCGCACCCTATGCAGATCTTGGAAATGTTATGAGCCATACTTATTCCTCCGGCAATCACCTAGAGTTCCTGTATTTGTATTCCATGGACATAAAGCATGAGTTTTCTTTTGATAGTGTAATCTTTAGTCCTAAAGCCCTTTGTATCTTCTACGACAAGATTTCCTTCTTTATCTCTGTAAACGAAATCTGCAACGTATATGCATTCTCTTTCAATAACTCTTCCCTTTTTGATACCGCCTCTTTTCCCAACGGTATCCGGCTCTCTCTGAGCCGGGATAAGTATGAACCTCTCCTGCGTTTTAAGTTCTGATATCTCTCCAGCTTTTTCCAGCAAGAGTAATTCCTGGTATCTCCTTGCCTCTCTCTTTGAATCGAACTTTACTCCGCCAACTTCAATCTTTTCGTTCCGGTACTTGTTACCTGTAATTCTTCCCCTATATGGGTAATACGGATTAGATCGTCGAGTTGCCATAATCTAATTCCTTTCCCTTTATTTTTATTTAAACAGGCCTTTCTGATGTCTTTATGGCGCCCGCCACAAAGTTGCAGCTTTCACTGGCGATCCCACACCTGCGGAATCCCTGAGGGCATGTTTGTTAACGCGTGAGTGTATAACCAAATTTTGTACCGTTTGAAAATACAATATTATATTCTCCGGTATCTTCGTTATAATTCCATTTTTCAATCTCACCTGTGATAACAAGCTCTGAAAGTCTCTTGTTGATCTTTTTGACAGCTGCGCTCTTGGAAAGCTTTCCTTCCTCGAAACCTACGCGTGCTTCTGTGCTGATAACTGGTTCTGCACCGCCATCATATGCCTTTATTCCCTGGCTATGTGAATTAAAAAGGATCGTTCCTGTAACTACTGCTAATACAAGAGCGGCAGCAGCCTGATGAACGACCTTCTTAGGTATCGTTATCATTTCGTTCTTGCCCATTAGTGTCTCCTCAACGTTTTTAAACTAAAATTCCAACACTTATATAATGGGTAAATTCAAAAAAGATAACTGCATTATAAATGACTTGCGAGAAAACCCCTTCCGATAACATCGGTCTTGGTAGTTCATTTCATTCAAAGAGTCCTCCACCTTTTCCTGGCAGAGTCGAAGCTTTTACTCCAAGTATAAGTTCAGTATCGCTTGCGACATGATCATCATATGGCTCCCAGAGTCCCTGACTTATAACGATTTCTCTTGTGCAGACATGCGCTGTTTCGGGAACGATCATTTTTTTAAAATCCTCATCTTTGAGTTTTTTTTCATACGCTCTTTTAACAGCTATACTGGTCTCAAACGGTCCTGCGCATAAAAATTCATCGCCAGATTCTTTATTCGTGACAAACATTGCATACTCTGTGTTCACGATCCTGTTCATTCTTAACTCCCTCCATCTCGTCGCATGCTTTGACAAATCTCTTATAAAGCCTTTTAAAAGGTGAAGACATGTCGCATTTACATGCGCCGTAATATTTTTTACTTATTGGATATAACCATCTTATACCCTGCTTAGTATATGAGTCCACAAACAGATGCAGAATATACCCAAATAAGAACCCTCCGACAAGTAAGGGATCAAAAGATGATAATACTGCAACGATACTGGTAAACATTAGACATCCCAAGAATGTATGCGGAAGCCTTGACCTGTGATCATAAGTTCCCTGGAATGGGCGCAGTATGAATAAAGGCTTGCCAATAGTCGATGTTTTATTGTCTATATCAGGAATAAGAGAGCCAATAACTGCCCCCTCGATCATTACCATTGCTTCATTTCCTGTGCACCCACCTGCTGCCGCAAGGAGTCCCGTCATGGCAACTCCTGCTGCAAGATGTGCCTTTCCACTCGCCATTTATAATACCTCTTTTACTTCTAATCCGTGAGTCTGGTCTGCAGAAATATGGAGACACATAAAACATGCAAATGTAAGAATCACGCTTCCGCAAATTCCAGCAACGCAAAAACCGGCCCATATTCCGACAACGGCCAGAATGGCCCTGCTGAAAAACTCAACAAACTTTAATACAACTTCTTCCATATTTTATCCCTCCGTATTTCCAATCAATTTATCAAGATGATTGTACACGATAAAACCCACGAAATATTTTTCTGCACAAAATAGGAGCGCTAAAAATCAGCGCTCTTTAGCTCTTGTTTCACGACGGACATGTACTTTACCCAATATCTTTAGTGATGTACTCAGCGATATTGAGTTCTTCGATTTTTAAACCGCACTGCTCTCCCGGCGTATACTCTATACCTATCACCTCAGCCAGACACATCTGGTCGGCACGATTAAGATAAAATAGATAATCTCCAATTGCCGGCATATCGGAAACTTCTCCGAAGTACATTTCTTCGGTAATACTATAAGGAATGGTCCCTATGATCACTTTGGAATCGCATTGAAGTTTTATCTGCTTTTCATTGATGATAAGGCTAAGAACCTGTCCTTTTCTTTCATAAACAACGTCATAAATCTGCCCCGTATCAGACACGCTTGATGTATCGATAATAAGTTCTCTCACCTCAAGAACACTATGGTCGATGTTCTTGGCATATTCGATATCCTGAAGCGGTTCCTGCTCTTGTTTTTGTAGGTCTCCGCTATATTGCACCTGGGTGTCTATATTTTCTTTTTCTTCGCCATCTCCAATTCCGTATTGTGCAAGGAATTTATTTTTTCTGGTTCCGGGCACTGCTGCCTTAATATTTTCTTTTGTTATTTTTTCAATAAATATATGGCAATTTTGCATGTAAAAGGTTCTGCTTGCCCTGTTATCCGAGTATTTTGCATATGCTCGTTCACTTTCAGAATATACAAGGAGGACCTCATCTCCTATCCTGACGTCTGGCTGCGAAGGTATTGTGTATGACGCAAAAAGATCTCCATCAGAACGATCACCCCATAACAGGAGTGTCCCATCTGCATTTATACTATTGCAAATGCAGCATTCTGATACGAGATCTTCCGGTATTTTGTTTTCCATCTGAATATCAGAAGCACTTTCTTTGTCTCCGCATCCAAACACGGATAAAAGCACTGCTGAAATCAGACAGATACACAATATTTTCTTTTTCAATTTTTCTTACCTGCTTTAGCCAGCTATCCTTCCAATGTTATCAGCTCTTTGTTCATAACGCATTTCCTGAAGCTGATCCTGATAAAGGCTGCATTGTCTTGACACCGTCTTGCTGATATTGTCAATATTTTTATAATACTGAGTTAGTATTGTTTTCTTGCTGAGCGCGAGTTGATAATCGCAGTCCGGAGCTTTTGATACCGGATATGAACGACATACTATATCCATCTTGCATATAAGTGGATTAAGATACGCCTGTACATTAGCACACCACCCAAGTATTCCCTGCATGGTTGCAAGATCACTTGAAGTAAGTGCTGATCCCTTACATGAAAAGCAGTCATCATACGTATCGTGAAGATAATCAAGCAGATCACTAGGAGTTACACTCTGAATATTGTTATAATTTACCTGTATCATTCTAATGTCTCCTTAAACTGCTTCTTTTTCCTGGTCAAGCTCTTGAAGCATGCTTTCTCCTAATTTCTTATAGCAGTCTTCACAAAGGCAAGCAGTTTTTTCAGGAGAATGTGCTGATAACCCAAAGTTTTTACCAGATGCCGCATTAGTCAATCTCTTTGCTCGAGAACCGAACGTGATAGACACTGGTTTCATTGAATAAACCCCGCAATAATCACATCTCTTTATATTCATACCTACTCTTCCCTGTTTCATTTTATTTCCTCCTGTTTTCTAACTGATGTTGTTAGTATACATGTCTGATCTTTAGTTTCATTTTTCTGCACAGTAATTTTGCCTCTGCATGAAAAAAAATCCGGCTTGCAGTTTTGCAAACCGGAAATCTATGGGGTGTGTGAAAGGATGGACTGGTATATCTTTCACTCCTCAGCCCACGGCATCCCTAAAGGATACAGGAGATGTATACTTAATGCCAGCATTAAAAGTATGATGAACTTTTGTAACTTGATATCTATTATGGAACATTTCTTTTAAAGATTTTCACGCTAGAAAACGATAAGGGTACACATGACACGTTGGGGAAACAGTCTTATATTTATAGCATAGCCACAATAAGATAAACCAAGGAGAATAAGATGAATAATAGTTATCCGAATTTTTTAGATGCGCTTTATAAATATCGTGCGAGAAAACCCCTTCCGATGAAATCGGATGTGGGATGCATCACCTTTTCACGAACAGCTGTTCGTGATAGAATAAGTCAATCGGAACCTTGAAAACTGTATATATGAGGTTGCACCACGAATCTAACAAACCAAGAGCCTGTGGTGTGTAAAATATACAAGGTGTTTAGTTCCCAAGCGCCACAAGCGCATATATAACACTTAAAGTATGCCGAAGGGATTTCCCGACGGAGTAGTGGCGCCATGGACGTGCCTTGCTATACAACTTTGGTATTGCAGAAACCATTTCCGATAACATTGGTGGTGGTAGTTCATATTGCAAAACAGAATGGGAAGATCATATTTGAGAGTTCCTGCAGATTAAATACAGATACCAGGGAAATAGTCGGAGTTAAAAAGGATGTTATCCCTGCTGACTTTGATGAAGAATTTGTGCAGTTATCCTTAAATGGAGTAACATGCCCTGCCGGCAAAAGAAGTGATATCAATCCAGAAGAAACCGACAGCTTCTGGTATGAATAAATGATATAGCAAATGCCAGATAGTAAGCTACCTGGCATTTTTATCATTTCAACTTACTTTACAAGATATTCTCTTGCTTCTTTCCCAAATGAAGTGAAGCTGTCTGGAGCGTTAATAAAATCTCCATTTACTTCACCGCCCTCGTCATCTCCATATACCGGGAATACGAGGATCTCGTCAAGCGAGCTCATATCTTTTGAAAACATGAACTGGATCTCTCCGAAGATATAACTATCATCTTCTTCAAGGCAATCATTCTTTGGAACTTTCCCTGCGTCTTCAAAAATCTTTTTAAGATCTTCCTTTGATACTTTTGCAAGGGCCATGTTGCAGCTGTTCATTTCTGTAATAGTGTCATAAAACTCAATCTTCATCTTTCTCTCCTTGTTATTTAACCCGCAAGTTCTTCAAGTCTGCCATCCCTGATAACATAAGGCCTGTCAGACAAGTATTCTGTTGAAGGAAGTACAGTCTTGTTTACATCCATGATCATAGCTTTCAGATCGTCTACTTTTCTCTCTTCGAGCATACTAATTGGCAAAACGATAACCTCATTAAGACTGCTTGGGATTATAAAGAAATCTTCGCCAAGTCTTTCCCTAATAGCATCTGCCACGCCATTATACAATATGGCCACTGCTCCCTGTTCGCAGTTTACAGTGTTGATAACCAAAAATTTTTCCAGTCCCCTTAAGTCAACCGGCATCCAGCACCCTTTCTGCCTAAGTATGTCGTTCATGCTTACGATTCTTGGTGGATTGATCACCGGGCTGTTTTTAATCGCTGTTTCAAACAATTCTTTTTCAGTGACGCCAATATGCTCTAGCTGGGCTTTTGTGATAGGGATAGAGCCTTCTGCTTCAGGAACAAGATATCTTACCATTACAGAAAGCTCATCATTGAGCTTCTTGTGAACAAAACCAGGGTTTTTATTGACGTTGTGGTTATATATAAAAGCAGCAATGCCCTCTAAAAAATCGTCCCTGTTCTCGAATTTCTCTATCGCGCGCGCCACGCTTGAAGAGTTCTTATATTGCTCTGATTCAAATGCATTCCTGAATATTTCAATGCCTTCGACAAAGTAATCTTCCTCTGTTGTCCGACCATTTTCTATTGCAAGAACATGATCCTTTGTAATAGATATAGTAGGGGCAATGCGGTCATCTTTATTCTTCTTGCAGGTGATAGCTAGTGCCTCAGGGCCCATATTGAGCTTATATCCAGGTCTTATATCTGGATAATAACCTTCTTCTGCAAGCCTTTCTGCAAACTTTTTAGCCAGTTCTTCAACTTTTTTTACCATTTTATCCATGTTATTCTCCTTATATTTAGCTCTCATTAAAATGTCCATCAAATTCATTATGTCAAATATTAAGTACAATAAAACGGACCTCGTGCTACAACATTAAAAAGGATCCTTACGTCAGTCAAAGAGGTATTTTATGGAAAGCATGACGATATATTCACAGAAAACGGATTTCCACTTATGGGAGAGCCGACTATCGAAGATATAGAAAAAATAGAAGGAGATAAGATCTGCTTAAGCCATGACCTGGCAAGGGTAAAGCCATCTATTCTGTTAAGGATGAGGATGGAAACCGACACCTCGTAGAAGAGGATATACCCAAAGTAAGTCCAAAGGACAGAAGCCAGATTCAAATGTGAACTTGCGCACGCAAAACAGGAAGCTGAGCTTGAAAGATAGGCGCAGCTTCCTGATATCGGCAAACATTTTTATTTTGTCGACAAGGCATCTCACCAGGTACGTGAAGTCGAAATTGTTGAATATATCCCCTGGATTTCTTCTGGCCCAATAGTAAAAGATACTACAACTGGGGACTTTTATTTAGGGGTAAAAAGAGACGAGCTGTTTGAACTTTCAGAATACGATAAGGCTCTTGGCAGGCTCAATTAGAGTCCCTGCCAAAGCAGTTTTTATGACTGTAATAGAGCTTAATATGCCATTGAATCGCGTATTCCTTGCTTTATTTTCTTCACATCAATCTTATCAACGCTTCCTGGCTCGAGAATATATTCTAGCATATCTTCCTCATCAATCTTCTGCCAGTCAAGGAATATCTTAAGCGCAGGGGTTAAATCCTTCATCTTTTTAAGCTCATTAACAGTATTAGGGATCTGTCTTTTGCATTTGCTTGTCTGTATACGGAAATATTCCTCTGCTGCTCTCTTTGACCTTGTGTACTTAACTTCTGCTATGGTTTTTGCGATAAGCTCTCTGTATGTTGCAAGGTGGTCTACTGCATAGATGTCTTCTTCACTTATCTCGTTTACTTTCTTCCAAAGCGCATCAAAAGCAACCTGATCCTCAGCTTCAAGTTCGTCCTCTATAAACTTTCGCATAAGTATCTGCTCTTTTTTTGTCAGCTCATGCTTTATTTCGTCAAGAAGTCTTTCTGCCCTCTCTTTCTTCGTTGGATGGGCTCTTTTTATTCTCCTCTTTCCTTCAGGGGCGAGATGGAACAGGGATTTTCTGTGAAGGTTGTCAACTATGTCAAAGACAACGCATCTGTTCTTCGAGCCTGTTGAAAGGGCCCTTCCAAACTGCTGAATATATATCTGCGATGATGTGGTACATCTGTACATAACGATGCCTGTAAGATCTTCTACATGATAGCCCATGTTGAGCATGTCAACACAGGCAATAAGGTCTATTGTTTTTCTGTGGTGCTTTAGGTTTAGATTATTTATATTATTCTGAGTCGTTTTGTTTTCCGATGTCACTACAAGTGTATTTACCGTATAGCCCGGAAATGCCTCTTTAAACCACTCTTCTACCTTTGTATATCTTTCAAGGAGTTTCTTTATATTTGGGAAAAAGACAATGTACTTCATGTAAGACTTTGCACTGACATATTTATCCGTGGTCTTTTTCATTATCTTGGGGATATTATGGACGTTACTTACTTCAAAGAGCCTGGATTTTAAGACTTCATCAACGACAATGTTATTCTTATCCTGTCCGGTAAGCCTTGCTGCCTGCTTAAAACTCGTCTCGATGTCATATGTACAGTAGATATAGATTGGCATTTTGATGATGCCGTCCTGTATAGCATCATGGAGCGTGTATTGGAAGACGCAGATACCCCTGAAGAACTCTGCAATGACGTCGAATGCATCCATCCTTTCAGGGGTTGCTGTTGCTCCTATTATGTGGGAATTTTTCTGATAATACATAAGCCAAAGGGCTCTCGTTTTGGTAAGCTCGCCTCCAAGACGGTGTGCCTCATCCATGATTATGAGGCTGTACAGAGGAAGTTCTTTTATCTGCTTTTTATCCATTCGCGCAAGCTTTGTATAAGTCATGAACCTGATGTTGTGGTAATCAAGTTCATATCCAAGTTCATCATATATAGCTTTCTTTTCCTCAGCTTCCGATTCATCTTCATCTTCAATTTCCCATGTCTCATCTATTGCATGCATGGCAGTTTTTTTGATGATCTCTGCAGGATAAAGGTAAAGAACGGTGTCATATTCCTGGGCAATTTCAGAAAGAAGCCAAGTTTTACCAAATCCTGTACAGCGAGGGACAGCACATCTGTTAAAAAGAGATAGTTTGTTTTTTAGATCTTCTTTGGTTCTGTTTCTTACGGCTTCAAGAATATCAGTGCTCATTCATGTCTCCTTTTTCAAAATGGTTTGCGTAGTGTGAACGTATTTCTTCCTTCGTGAACGCATATTCATTATTGCAGCATGGGCATTTGAATGCATAATATGAAATACCATCTATTTCAAATAAAACTTTCTTGCCTGATGTAGAGTATACTTTAGATGTATTGTTGGGAATTATGAGAGCTTCCCTTATCCCCCATCCGAGTTTTAACCGGTCTTTTATAACTCCTTTTTTCTGTCCCCAATGCTCCGCCATTTCGACTTTGCTTTTATATACATTTCCAAGGTGGTCAGTGCAAGTATAAATGTCTTTTGTGGTCAATGCTTTTTCTAAAGACCACCCGTCATATATAATTCTATGGCGATATGTTTTATCACTCACGCCCCAGTGCTGGCACATTTTGATTTCAGATTCAAATACGTTTCCTAAATGATCAGTGCATGTTTTTCTTCTTGCATAATCGCCCTTTGATAAAATTCTTTCTAGTGGCCAATCACTTCTTTTACGTGACTCGTATTGTGATAGTGTTATTCCGTGATGTTTGCACATTTCTGTTATGGATTCAAATTCATTTCCAAGATGGTCTGTACAACGCACTTTTACCGAGACTTTAGGTGTTAAGGCTTCTTTTAAGCTGACGCATTTTTTAATATCCCTTGTAAAGGCATGTCTTTCCACTCCATGAAAGGCACACATTTCATCCAAAGTCGAGAATTTATTTCCCAAGTGGTCAAACCATTCCCTTTTCAATGTCTGTTTTTCTTTTTTTGTCCTGCAGAATATTTTGCCATCTGAATCTTTTTTGTAATATATTGCTGCCTTGCAGAGAGCTTCTTCGATAGTTTTTCCCGCACGTAGTCTTTGATAATATGTGTTTTCGCTTACGCCATGAAATGCACACATTTCTTTTTGGGTGTTAAAAACATTTCCAAGATGGTCTATGTATTTTTCTTTATTGTGTGGATTTAGGGCTTCTTCTAACGATTTGCCACTTTTTAGCCGGTTTAGGTATAAAGAATAGCTAACGCCATGATACCTGCACATGTCCGTTGCTGTTTCAAATTTACGTCCAAAATGATCTTTAAATACTTTATGAACAGGCTTAATCATCAGCGCATCTTGCAAAGACCATCCATTCTCCATTCTTTTGTGAAGCCTCACACGACTAAAGCCGCGTGCTTCCTATTGCCACAATCTACGTTGTGGTTGCCTTTTAGGGCATCGGACTACGTTTCTGCCCATACGGCTAAAACTCAGTACTTAGGCAACTAATATGTTGTCTAAGACCGCATTTAAGCTAATAAGGTCAGCTAACGTGCAGGTGCTTCTCTTAGAGCACTGAGGGACTTTAGCCTCAATGTCCAACCTGTCCGTCACCGAACAGGATTTAAAAATTTCTCGTATATAATAGCGGGCTGCTATATTATACGAAGCATTAAGATCGCAGTTGTATGTTTTGCCATTTTGGAATCTACACAAACTGTATGTGGGCATATCTGCGTCCTTACCTCGAAGAACTCTGCCACTGCCATCGAAAGCTAGTCGTGATGTCCCCCATGCGCAAATATGAGATATCCTCATACTAAGTCTGTGAGCCTTGTCTGTTACCATAGATTGCACGTACTTTGCCTTCCACATATGGAGCTTTTGTTTCTTAGAGCCACGCTTTTTACCTGCAAGGTCCAAGTGTTCAAAAACTATGGTGTCAGCATTGTACATTACGGCTGTATCTATGATAAAGTTAGCTGTTTTAACAGCTATATCATCGTTAATACCTTTAGCTTTAGCCCACAGCCTCGGCATCTTACGGTTGCCATATTGCTGGGCTTTCTTTATACGGTTTACAGCATGGTTCAAACGGTCTGTTTCCCTTGGCAGTCTAAGGAAACGTCTGCCGTAGATAGTGCCTTTTGAATCCATGATGCAACACGTACATGCTGAATTTAAACCAAGGTCAACGCCAACTACAAGGCTGTTTGTATCTGTAAGAGTAGCCTTTTCTTCAAACGGGAAGTCTAAAAACCATTCTTTACCCCGTTTCTGAAGCGTAGGAGCGCACATCTTACGACCATTACACCTATGATAGATATAATCCATGTCTGATTTACGAAGATTAATGGATAGCCAATTCCATGTATTGTTATGGTATATCTTAATCTGTGCAGAATAATCGTCTGCGAGATTATACATTCCTATGCGATATAGGGATGGATACACGTACCCACAGTTATTAAGAGTAGGTTTCTTACCATTAGGATTTAACTTCCAGTTAGCAAGGTTAGATTTATAAGATGATACTTTGCCTATAGCTTCAGATATTGCTGCTCTGCGTATATATGACGGCATCTTATAGAATCTGGAATCGAAATCGTATTTAGGAGAAGAGTTCTCTTTGGTTTTATGACAAAGCGACTCTACATGCATCATTTGAGCCTGATTACCTTTTATGACAGAAACTAAGTCCCATTCAGCTAGGCATACATCCATAAGAAAATTGACAGCATCCCTGTATATAGTTACGGTCTCAGAAAATATATGATTGTATTGTTTTATTTTAACGGAATACGTGGAGTATATCTTCATGTGTTACTTTTCTTTCTGACTGCTTATATAATTAGTGACCTGCTCTTTAGTGCGCTCACTTACAGTTGCTACAAAATATGATGGATTCCATAAATGTCCACCCCAAAGCTTAGTTTTGATTTCTGGATGCGTAAGAAACAGCCATCTTGCAGTATTGCCTTTGAATACTTTAATTGCATCTGAAATCCTACATTGAGGCTTACATTCTATAAGCATATGTATATGGTCAGGCATTGTTTCCATAGCAAGGATTTTAATGCCTAAATCTTCGGCTGTACGGTAAAGATGTTCTTTAACATCTGACTCTATATTGCCAATAATAACCTTCTTACGATACTTGGTACACCATACTATATGGTACTGCAAGCAGTATACATATCCTCTACCATGCGTCACATCTGAATTTATTGTAAATATGCTATATTTATCCATGTCTGCATAATACCATACGTAATTAGCAGAGTCAAGAAAAGGCGGCTAACTCATGACTAAAGTCACGAGTGTGCGCCGCCAATGTTATCAAATGTTCCTTGTGCTATTTGATAATGTTTGAGCATGGCGCTTTTTGAGGCAAATATATTTCCTAAATGGTCTGTATATTCAGCGATTCTATCTTCTGCCAACAGTTTCTTCAGGTTTCCTCCTGATTTTATGCAGGCGCTAATTGCTTTGGGGCTTTTCCCGTAATATCTTGCCATGGCAACCATTGACTTAAACTCGTTACCCAAATGATCCTTGCACGGCTTTGAACCCGCATTTCCATGGTCTACAGGCAGCATTAGTGCTTCTTCAAGAGGCATTTTGTTTCTTAACCGATATTCAAGGCATTTAAGAGGTATCTTATATGCTTTTGCCATTTCTTTGATGGATAGATATTCGTTACCAAGATGATCTTTTACTTTTAATTCTTCTCTGGGAGCGCCGACGGGTGTTGTGAGAGCTTTTTCTAAAGACCACTTTTGTTCATTTAATCTATCAGATAAAATGTCGGGATCTATACCATAAGCTCTTGCCATGGCAGAACGAGATTTATATGTTTTTCCAAGATGGTCTGTACAGAAATATGTTTTTAATGGTCTTGTCAATGCATCTTCAAGACTGTCCCCACGTTCTATGCGGTCTAAAAAAGTCCATTGATTGATTCCATATGCCATACACATAGCTGTCTGTGATGGATATGAATTACCCAAATGATCGAAAACAGTAGTATCTTTTTTGCTTGTCAGAGCATCCTTTAGGCTCATGCCATTCTGAATATTTTTCTTATATGTACAGAACGCAATATGGTGTGCTTTGCACATTTCACTTTGGTTTGCATACACTTGCCCTAAGTGATCCGTACATTGCGATTTGCAGCCAGCCGGAGTTAGCAACGCTTTTTTTAAAGGCCAATTATTCTTTAATCTGTTTTGCAGAGTATCTGACCGCAGATTATAATGCGCAGCCATTTTGCCAAAGCTTTCATATTCATTTCCAAGGTGATCTTTGCATGCATGAACTCATCCTCTTAGTCTGTATAGAAAAGCAATACATTTATCTATCGCCTTATTTTTCAGGCTTTTCTTTTTAGGAATAGTTAAAGCTTTTTCAAAACTATACTCCCGGCGAGGGTAGATGTGCATTTTTGATGCGTCAATACCATAATATTTACACATTTCCTTTACGCTAGAATAGTTATTTCCAAGATGAACAGTAACTTTGGTATTAGTCACAGCCTTACCTCCTTGTTTTTAACATGCATAAGTGTATGTGACCTCATTTCAGCTTCAGTAAAGACATGTTCTTCTTTGCATATAGGGCATTCGCAGTAATAATACATAATTCCATCCATTTCAAATGCCTTACCATGATGCTTACAAAGAAACTCCTTCCCCGTAGGGATAAGCAGTGCTTCTTCCTGTGTATATCCTGACTCTATCCGTTTTATGTATACGTCTCTTTTTATGCCATAGGTGTCACACATTTCAGTAATCGACTTGTATTTATTTTCCTTATGGTCTGTACAGAAAACTCTCCTTCCATCCTTTACAGTGAGCGCCTTTTCAAGACACCAACCGTATTCAAGTCTGTGCCACACAACATCTACTTTTTGACCGTAAGCCTCTGCCCTTTTTTTATAGCTTCTGTATACCTTCCCGAGATGATCCGTACAGTATTCTCCTTCCTTCAATGCTTCATAAGGGGCATCGCCTACTTTTATAGATAAGGCAGCGTCTTCATCCCAGCCACGACGTAGTCTGCTTTTATATGTCGATTTGCTTATCCCATTTTCCTTAGCTTTTTCTTCATCAAAAGTTATCCTTGTTTTGTCAGGAGGCGTTATGAGTGCATCTTTAAGACTCCATCCCCTATCAAGACGCTCTTTTAAAGTGGATTTTTCGAGACCGTAAGCCCTTGCCATAGCTCTGAATGAAGGATAAGACTTTCCACGATGATCCTTGCACCCTACTCTTCTTTTGTTTCCATGATTTGAAGGTGTTGTCAGTGCTTCTTCAAGGCTCCATCCTGCAGATAGTCTTTCATCAACCGTGGTATTTCCAAGACCATAAGCCCTGGCACGTTCTTTTTTAGAGCCGTATTCTGTTCCGAGATGGTCAAGGCATTTAGGCATAAACTTACCCTCTTAGTCTGTACAGAAAAGCAATGTAGTCGGTTGCCCTGGACCGGTAGTCTACGTGTAGCCCGTGGATTTAAACCATAGTGCTCAGCCATTTCCTGCATTGATGAGTATTCTTTTCCTAAGTGGTCACGTACTTTCTCTAGTTGTTATCTTTCAAATATCCTTGTTTTTTATATGCATGAGAGTGTGTGCTCTGATTTCTGGCTTGGTAAACATGTATTGAACTCCACATGCGTCACATTTGTAGCTATAATATTTTTCGCCATTAAAACTAAACTTTTCTTTTAGGTTTTGCCATTTCCAATGGCTAGGGATAAGAATGGCTTCTTCCAAGGAATATCCTTCTTTTAATCTAATCCGTGTTGTTGCATAGCAAGTACCATATGTATCCGATGCTTCTTTGATTGTTTTATATACTTTATCGTCAACGATATATTGGAACGGTTTTACAGTCAGTGCTTCTAAAAGCGTCATACCATCCTTTATTCGGTTTCTAACTGCATTGTCACTTTGCCCATATGCAGAGCACATAGCTTTAAAGGTATCATAATGATTGCCAAAAGGATCTTTACATGATTTAAAAAGAGGATTTTTTGCAGCCAGCGCTTCTTCAAGTGATAATCCATGCTCCAATCGTTTTTTTATAGTTTCGTATGATATGGAATACGTTTCACAAATGGTTTTTATTTTTCTGTTTTCTGCGCATCTTTTTTCCTTACTTCTGTAATCTGATAATATTTGCTCTAGTGGGATTCCCTTTTTTCTTTGGCGATAGAAGTATGCTGTTGATATGCCTGTTTCCTTTAAGAACTGTTTCAGACTGCCGTATAAAACTTTGCCATCAGCCGCAACTTTCACAGAATGCCTGTCGTGCCCGTTTTGAATAGTCAAAGCTTCTTCAAGCGTGAACCCATATCTTATTCGCTGAACGAGTCTTGTATATGGAACGCCATATATTTGAGCAAGCCTCTTAAGGCTATATTTTTCCCCTTTGTATATATACATGTCTTTAAAAAGCGGAGTTGTTAATGCGACATCTAAAGCCCATCCTTTTCTTAATCTACATCTAACGGTATTGTCGTTATGCCCATATGCTTCACACATTTTCTTGAATGATTCATATTCATTCCCTAAATGATCCATACAGAGGATACTAGCAGCATTACTGGGACTTGCCGGATGAGTCAAAGCGTACTCAAGGGAGTAGCCGCACTTAATACGGGTTACAAATGTACTTTGGTTAATGCCATAGCATTTGCACATTGCAGCTTGAGAAGAGAATGGATTACCAAGGTGGTCACAACATTTCATACATGCTTTCCTTTTAGATGAATATGAATGTGTATAATTTATTTCTTTTATAAATTTCAGCGAGAAAACCCCTTCCGACATCGGTTGTGGGACGAGTAGAAACCATTTCCGATGTCATTGGTGATGGTAGTTCATATTCCAATATTCATATATTTCTTTTTTAGATAAGAATTTATTGCCCAAATGAGCCTCATACATTTGTTTACCTCATTTGCGTATGCTTGTGGTGATGAATATTTATTTCCGTAGCGGTATATATATGCTCTTCATGACAGAATGAACATTTGTAAAAATAATATCTTTCATCTTCTACCTTAAACGCCACTACTATCTTGTTCTGGCGAATATCCGGAAGCAGCAAGGCATCTTTTAAAGGCCAATTCGACCTCAATCTACACGACAGTACATTAGCTTTTATTCCATAGGCATTAGCCATGTCTTTTAGACTGTTATATTCTTTTTCTTTATAATCCTTATATCTTTTATGTTCTTTGTGTATGACAGGTGTTAATAGGGCATCTTCCAAATCCCATCCCAAGTTTCTTCTTCGTATGTAAGATTCAAGACCTAGTCCATAATGTTCGCACATAGCATGGAGGGATGCAAATTCACATCCGTTATGATCATGCACCTTATGTGAGCGTTTTGGTCTTGTAAGTGCATCTTCTAAAGAAACACCCCTACTGATCCTGGACTCATATATACCTACCGTTATACCGTATGCTTTGCACATTTTATTTAAAGTAGGGTATATGTTACCGAGATGGTCTTTATAACAATGCTCTTTCACACATTTTGCATGTTTGATAGCCTCTTTTATAGGAATGTTTTTATCTAGCTGTCTTTTAACTATCGTTGGCTCTACATTGTAATACCGACATAAAGCATTAAGGCTTTTAAACTCTTTTCCTTTGTGGTCGCGCAGCTTTTGGCAACTATTATTTTCTGAGGATAAAGCTTCTTTTATACTGCGTCCCTGTCTTAATCGCCATTGATATGTTTTGACTTCTACACCATATTTGTTGCACATCTCTTTAACTGACCTAAACTTATTACCAAGATGATCTATATATATATTTGTATCTGCTATCTTCTTAGGGCAAAGGGCATCTTCCAATGAATATCCATGCTTTATTCGGTCTCTAAATGTTTCTGCGTTGACGCCATGATACCTGCACATAGCTTCTTTGGATTCAAACTCATTTCCTAAATGATCCCTGCACTTTATTTTGACTGAATAGTTCTGTTGGCTTAATGCTTTTTCTAAAGGCCATCCGTTTTTTATACGATCTCTAAACGTTGCAGGATGTATGCCGTAATATTTGCACATGGCATTCTCCGAGGGGTAAATATTGCCAAGGTGGTCAAAACATTCTCCTTTACAATGTTCTTTTACCGGAGTAACAAGAGCTTTTTCAATATTCATCCTTTTTAGACGGGCTTCTAATGTTGTGGGCTTGAGTCCATATTCCCTTGCCATTTCTGCTCGCGTTTCATATTCATTTCCCAGATGATCCTTGAATTTTATTTTGAGCATTTAGCGTCCTCTTTGCACGAATGCAAGTTTTATCGGGCGGTGTTGTAAGAGCCTTTTCGAGCGACCATCCGCGTCTAATCCTTGCCTTCAATGTACTCACTGCAATACAATATTTCTTTGCCATAGCTCTTAATGACGAATATTCATTATTATTGTGGTCAGTGACGGTTTCAAGCTTCCGAATTGGTGTTTTAGTGTAGAGCGTCTCGTTTATTTCACCACTATATTTATGTCGCAAATAATGCTGTCTGCATTCTGCTGGGGTAAAAACAAATTGATTGTTACAGGTAGGGCATTTGTATGTATAATAGTCTTCTCCGTTTAATGAAAATGAAGGCCATTTTCCTCTTAAGAGGATTATTTCTGGTGATATTTCAAGCGTTTCCTCTAGCGTCCATCCTTTGCGTAGCCTATGAGTAAAAAGGCTGTATTTAAGTCCGTATGTATTAACCATTTCAGATTTCGATTTATAAAATATGCCTTTATGATCTGTACAGGAATACAAATTAGGGCTTGTCAATGCTTCTTCAAGTGTCATTCCGGCTTTAAGTCTATTGAAAAACGTGGTGCTGTTAATCCCGTAATACCTGCACATATCTTCTTTTGAGGCAAATTCGTTTCCAAGGTGATCGTGATATTTAGGCATTTATACTCCTGTTTCGCACGTTTAGCTTGCATTACATTCTAACTATATTATAAACGGCTTATATAAAGGCCATTACATAGTAAAAAGCTCCGAAACACAGTCCCAGAGCTTTGTTTAATCTTTTCTTTATACTTTAACAACATATCATTAATTTTCTATTAAATTTTCCAAGCAGGACTTCCCTACCCTATCAGATAGTCCTATTTACATACGCAAGAGTGTCTATGATTGAACTACCACCACCGTCTACGACGGAAGTGGATTCCTGCTTCAGTCACCACTGCGCGGGACTGTTCTAAAACGAACAGAAAGCTATACATTAAAATCTTGAAACCTAACTACTAGGTAATTTTCTATGGTTCTAAAACGCCATGCATTTGGTAATCCTCACGAATCGCACCTAACAAGCAGGTATTATTTTAAAGGTTCTAAAACACAAAAAAGAATGCCAGATGTCAAGCACCTACCTAATTACTAGGTAATTTTTTAAGGTTCTAAAACAACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAATTTTTAAGGTTCTAAAACGCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTATTTTTTAAGGTTCTAAGACAGTCCTTGAATGGCTAATCAACTTGCCACAACCTAATTACTAGGTAATTTTTTTAAGGTTATAAAACAACAACAATTGAAAGGAGAAACGTACACCTAATTACTAGGTAATTTTTAAGGTTCTAAAACGCTTCCGACCAAGAATGGGTCGCCTGGAATACCTAACAAGTAGGTATTTTTTAAGGTTCTAAAACTCATTGCGATCTCATCTCCTTTCTGCGACGACCTAACAAGTAGGTATTATTTTAAGGTTCTAAAACGTCAATTGTAGTATTATGACATTATCAAACCGCAATATCTTGCGCCTGCATATAATTTAGAAATGCATCAAGAAAATCTCCATCACCCCTATACTCCTGCTTGAACATGAATTTCTTTCCAAAGTTGTAGGTCGTATTTTTCGACACATCAATCTCAGTTCCGGTGATCGGAGAGCGATATATCTTTTCGCCATCTTTCTTTGTGATTATTCCATACAACGCATTTGCAAACCATTTATAGATAAGCTCTACGCTCTTTCCTGAGATAGCTGTCTTATCAAGGAATTTTTCGGCCATATTGCCATCAAACACAGCCTTATCTTCAAGGAGCGCCGGAATTATCTGCTCCCTTACGATATCATTTACATAAACATATTCCCCTTTATCCTTGTCAAAATAACTTCCATCTCCCGCTATTTTAACAGTCCACTCTTTCCTATCAAGGAGCCTTTTTGTCGGATATTCTTCAAGATTGAATGTAAATAGCATCTCTCCATCGTCAATTCTTATATCTTTCATTTTTGCAAAGAACTGCCGCTTAGACTGCATTGTAATTAGTCTTGTCTTATCAAACACATCAACAAAGCCGGTATCCGGACAGAGCGTCCTTGTGTACGCATTATTAAGGAAATATATGACACCATCCTGGTATGAATTTCCATTATTGTTGGAGACCTGTATTGGATTTGATATCGAGCCCGCTTCACCTTCTTTTATGGTATTAAATGACAGATCTGACATCCGGGCACAGAGTCTTGCTTCAAACGCCTTAAATATCTGTTCATCAAGGAATGAGAACTTATCCTTAAATGTAGATGACATGGATTCAACAACAACTACCGCATTGTATTTTGTGGCAAGTTTACTGATCTGAGTAACAGCAAGCTCAACATATGCTTCCTTTAGTCCCTTGGAAGATACATCATACTGCCAGAGTCTTGTTTTATCATGATACTTGATCTTTGTCCTTTCTTTTAAAAGTTCCCGGTAGTTAACCCCATCTATCTCATTCAAACTTTTTTCCTCAAGTACATTGTTCTTTTCATCAACTACGGCAACATAGGTAAGGTCTTTTAGGTTTCTTGTCACAATAACCGCCATTCTGCTATCCTGTGTATCTTCTTCAACCTTATCATTTATATAATCCAGTGTCCTTGCTGAAATGTCGGCATTCTTGGTATAAGACAGGGATAAGAAAAACTTATCTTCGGTATATCTTCTATTTCTGATGATATCCTCGTTTGCCTTCTTGATGGCAACATCATGCTCTGCCAAATATGCTTTCGCCATGATAAAATCTTCACTGCTAATATCAAAGTTATTCTTCATCTTATATATGGCTTCCCTTATATGCATAGGGATATGTTCACCATTACTGTCCCTTAGGGCAACCAGTATACTTCCTTTTTTGTGCGTTACCCTTCTTGGAAGGGATGCAGCCCTGTACTGAATCATGGCCCTTGAATTTAGGAGCATTGATGTATGCTCCATGTTAGAATCCGAAAACAGCTGGATAAATGTCCTCTCGTATGGTTTTCTAGGTCTGTTATAAAGAAACATCGAACGAACAAGGAATAATAGGCCCTCTTTTTTATCCACCATATCATTGATACGTTCAAAGGATACCGGGATCCACTCCATTGTGCAGAGCCTTGTATCTACATCCGAGAAGAATTCACCGATATCATTATATTCATCAGCTCTCTTGAGTCCTGACATATTAAAGCACGAATATCTGGTATACACTGCTATGAACTCTTTATAGACATCAATAAGATACCTGCAGTCATCCTTAAATTTCTCTTCAGTCAGACCATCTATTCCTATATTTGTCTTTTTAAATGTCCCGTTTTTAAAGATATCATATGCTCTCCTGTCGATAGTAAGCGGCTTTGACACATATTCTTCTATAACACAGTTCTTATCATTCTTATGCTCCGGCGACTCAAAATATGGTTCCAGGATACACTTGAACAAAGCCTTAGGAAGCCCAAGGAAGCTTTTCGCACCCTTTCTCTGGACAAATATCTGAGCATCTGTTTCATCTTTTGTTTTAAGATCTACGGGTTTTACATCTGGGGTAAGAACAAAATAGTAGTATTCATCCCCGCGCCTTATCATTGCAACATCGTTGATCGCAAAATTCTCTTCTCCGTTCCACCAGTGAGTACGAAGCCTGGCGGGAGTGCCAAGGCATGATGCCATGATCCTGGCGTCATCTGCAGGAGATTTTGTCACGTAGTTTCGGCACAGATTCTCTGCTTTGTATGTTCGGTTTGCTTTTTCAAAGATCCCGTCAAACGTGTTATAGAATATTGGATCCGCCTTTTCATCATTCCCGCTATTTATGATGCGCAGCGCACTTCTGAATTTAGTCAGTTCATCATAAAAAGATACCAGGGATTCCTGGACGTCGCGATTACCCTTTATCCCCCTTCTACTTTTTAGGATATCTCTTTCAAAAGTACCGTATGCCTCTTTTATGCGCATATAATTCCTTGCAAGCTCATCCCGGTAGAGAATAAACAGTCTGTCATCACCTGTCATTTTCTGCAGACCATCAAACGTATGAGACTCTTTTGCAACCTTTTTTGGCACAGCATTTACAAATTTATCGTACCTTGCCTTTTCGCTCTTGGTCCTTCTGGGAAGAACCTCAAGAGTATTCTTTTCGTATTCTTCAAGCAATAGTCTTATCCTGTCATGTTCTCCATAAATAAGCTGGGAAAGAACATGCGTCTGATTGGGGCCTACGACAATAAACAGAGTAATGTCTCCTGGATCTTTGGCATAAAATCCATTTATCTTTTTGATATTTTCCCATTGCTCCTTTGTCTGTTCAAAAGCTTCTTTTGTTACCTGAACAACCTCCTCGTCGGAATCTATATGGTCTATGGTAAAAGCTTTCTCGCGCTCTTCAAGGATCTGCTTATGGAGCTGCTTAAGAATGCGAAAAGGCTTTTCCTCTAAGTGTTCTGATTTTATTTTGATATTCTTTTCAGAGATAGTCTGATTTATGCCTTTTTCCTTGGCGCCATCTTCATCCATTATTCCGGATATCAGCCTGTTATAAGAATCGATATCTTCCTGAGAAAGGATTTGATTGTAGTAGTCGACAGAACAGATGCTTTCGTATTCAATCGCAAATGATACCGCGCCTCTTTCCAGGGCATCCTGCATCTTGGGAATATTTGCAGCATATATCTCAAAGTTTTCAATGACTCTTTTGGGCATTGACTGTTCAAGGGTCGTGATCCTGCTTGTAAGAAATTTGGAAAACAGGGCAAGATAACCCTTGGTTTCAAGTATGTCGGATAGGATATTCTGTTTTTCTTCGCTATCTTTATGAGTCTTGTCTATGAAATCATACAGTACGCCATTTAAGTATTTGGCAGAATTTATCTCCGAAATTTTCCCAATTCCCTCAGGAAGGTTCTTTATAAGGGTTTTAACAATCTCCTTTTTAAGTCTTTCGCTTTCCTTGGCGTAAGCTTTCTTGTCTCCGGAAAGAAAGTGCTCATATAGCTTTTCAAATGAAAGTTCGCAGTTTTTAAGAGTATCTCTTGCAATGTCTTTTATGCCTTCATCGATCACAGGCTTAAGTCTTTCTAAAAGCGCGTAAATTGCCTTATCCTGCTCAAGAAGATTGAGCTCTTTGATATTCCGCAGTGTTTTCCCCTGGGGTCTAAGCTCAAGGCGAAGCGATTTTGTGATCTGATTTCTTTTGGTGTAGTTTTCATATAAAAGCATAGCATTATCCCCCTTTATCTTCATTTGTCTGTTGCACAATACTCTTACATACTTAGTTAATTATATCGCACTTACGCACATAGTTACACTCTTTATCATCTATTAAGGGCAATATTTAGGGCAACAAATATGTACAAATATGTATATAATTGCATATTTCTCTTGCATTTATCGAACGTGTGTTCTATAATATTCATATAAATCCAGGGAGGAACAGGTATTACATGATAACTAAAGAAGATATTGTTAAAGCACTGTCTGAAGAGGGGTATGAAGTCCGTCTTGTAACAAAACATAAAAATCATAAGACCAAAGAAGGTATCACTATAAGGCAAAACGAAGAAATGACCGCGCCAACGTTATATATGGATGAGATTCCGCTCGATAAATATACAGATCTTAAAGAGCTGATATCAGACATCAAAGATTTTTTATCCCGTCAGTCCACAAGAGGAGACGACCTTAAAAAGCTCGCTGAAAATATTGATGACTATAACACAGTCAAAGATAAGCTATACATAGAGATCGTTTCTGCAACCGATAATGAGGAGTTTCTAAGCTCCATGCCGCATAGGAAAGTCCTCGACTTTGAAGTGATATTCAAATTAAAATTAAGCGATTATGCAGTTGCCTCAGTTTCGAATGCACTTTTAGAAGCTTGGGGAGTAGATATAGAAACGCTATTTAATGATGCAATGGCAAGCAGTGAAAAGAATATGCCTTACGGGATATGCCATGTCAGTGACGTTATCCCCAAACCACTCACATCCTCATTCATCAACGTTCCCATGTATATAGTTTTTAGACCGGATGACGAAAACGGCGCAGCAGCTATTTTATATCCCGAATTTCAGGAGTTTGTTGGAAAACAAATTGGCGGCTTCTATATACTGCCTTCTTCAATACACGAATGCATCATGGTCCCAGACGCGTTTTACCAGCTGGGCGGGGCATCTGAAGATGTTCCTGGCGCTCTAAAGGAAATGGTAAGCCTCGTCAACAAAGAGTGCGTACCAAAAGAAGATCTTTTATCTGATAACGCATATCATTATGATCCTAACCGAAAAGTTCTGGAATTTGCAGACGAATATTTTAAAAATATCAAAGATGCATGATAATTAGGCGAGAAAAATATTAAAGGGCAGCAGATATTTCTGCTGCCGGATATACATATATTTATGCTTGCAACTAAAATTTTATTAACATTTTTATTGCACAGGGCATAATTGCAGAAATAAAGAAGGTTTGCATGATTTTTATTTTTCTAACAAAAATGCTCCCAACAATGTTGAGAGCATTATAAAATTTAGCGAGAAAACCTCTTCCGATGAAATCGGTTGTGGGATGAATCGCCTTTACGTGAACAGTTGTTCGTGATAGAATAAGTCAATCGGAACCTTGAAAACTGTATATATGAGGTTGCACCACGAATCTAACAAACCAAGAACCTGTGGTGCGTAAAATATACAAGGTGTTTAGTTCCCAGGCGCCACAAGCGCATATATAACACTTAAAGTATGCCGAAGGGATTCCGCCCCAACGGAGTAGCGGCGCCGTGAACGTGCCTTACTATACCGCAAGGTATTGTAGAAACCATTTCCGATTACATCGGTCTTGGTAGTTCATGTAAATATACATCTTATTCAGTTTTAAACCGCTGCATCAGTGGCAACAGGATACATATCTTTAATTTTGACGCGAACGCCAACATTTCCTTCGCCGTCAACATAATCAAGAGTACAAAGAAGCTTCTTATCACCCTTCTTTTGATCCGCTTCAACGGTCCCCTGCGTGCAAGCGCGAACGCCATCAATATCAGTATCGATCTTAAATCTGTCACCTTGTTTCCATAGTCTTTTCATCTTTTTCTCCCTTCTGAGCTTAAGCTCCAAGCCCATATAAGACTTCTTCATCCATGATGTATTCTGGTTCGCGGTCGACTTCTTCTTCGGTGATCTCAGCACCCATTTCCTCTACAAGGTAATTCTTTAGGCAGATATTTTCAAGATCACTGTTTTTATTGTATCTTGAGCAAAATGCCTTACCTTTGTACTTAAAATAGAACCTACTGTCACTTCCGATATCTCTTCCACACCATGCACATTTGATATCTGGGTTTGGATATTCTATTCTTCTAGCCATGTTTATTCTCCTTTATGCAACCTCTTCGTCATATACAGTTCCATAAAACAAAGTCTCTCCGATCAGGCTCTCGAGCGAGCCCATATCCCTGTTCATAAATTCCTCGAAGTCATAAGCATTGGTCGCATGATAGGGCCCTTGTTTATCTTCTCCGGTGATATGGACAAGCACCTGTCCGGTAGTACTTTCCTTCCAGATCTCAACTGTATCATCGTTATACTCAAATTCCTCTGCAGAATCGTATAAGAGAATATCGTTTTTGATCTGGCCTAAGAGAAGCTTTCCTTCCTTCTCTTCCTGTCTTGCTTCAAGAAGATAGATGAGCGTACGACAGTCTTCTTTTTGTGCAGTAGCAAAATCAATGATCTCCTGCACTGCATCATCACTGAAGTCGTCGTCGTAGCGATATGCCTTATCTACAAGTTCCTTTGCGTTACCTTCAACATAAGTCTGATCTATGCATCTGATTGCTTTCTTCATCTCCATATTATTCTCCTATTCTGTTATCATCCCTGATGCTTACGCACCAATCTCTTCGTCATCCCAGAACTCGTCCCACATTTCATCAGGAACTTTGTTCTTTTCATCAACTGTACCTTTTGTTTCGATCTGGTCCAGGGCTGATTTTCTAGCTCTGAAGTTCCTGCGCATCTTGTTTGTCGCAGGAGCAAGATCAACTATATCCCAGAAATTTACTTCATCCATCTTTTCTCTCCTTTCAAATAACCGACATATAATTTAATGTCTGTATCATGGAATTTCCTAAAATAAATAAAGCGCCGCCATGCTACCCAAAGGGCCAAGGCTTGCGCTTTAAATTTCAGCTATTCGCTTTTCTTTAAATTCTTTATTTTAAATTTTTTAATTAAGAATTTTCTACATAATCAAGTATGCTCATCATAAGTTTGCTTATAAGATCATGCTCGCGTACTCCAAGAGCCTTGTATTTTACAGTAAGCTCATCCATCTTACCTATCGCTCTTGTCCAGTCTTCATCCGTCATATCAACTCTCGGCTTATCAAGTTCTTTTCCAAGCGCCCACAGATCCATACACATATTGTAAAACAGCTTTTTCTGATCCATTCATGCACCTTCCTATTCTCTTCCTTTGCGGCGCATCTCCATTACGTACTCTTCTGAGCTTTTATACTGGTCAAGCTCTTTGATTATTTCATACACAAGCGCGGTATTCCCTACCAGAAAAGCCCTGCACACTAATGGTTTGAGGCTGTAATATTTAAAGGGGACCGGAGCATACACCTGATATATTTCGCCACTGTCTTCATAGACCTTTTGTGTATGGTGTTTCCCTGCCCCGGATTCCACATATATTCCGCTAACTCTTGTACGGTTTGCGTAAAATTCCTTGAGCCTGTTAGGGCTATAACCTTCTTTCCTGTTTCTTAGGATTTCGAGTACTGCCATGATGGTAAATAGGGAAAAGAAAAATGCTATAAACCAAAGGCTCGAGAGCTCTCTTTCACCTATCTTCATTACAGGAAATTCGCCAGCAATGTTATAAATTACAACTGAAAAAATCAAAAATCCAACAGTCGCACATGCAATAGTTGCCCACAGCTGGATTCTGATTGTTTTGTTGCAAGCTGTCTGATATTCTTCAAGGCTGATGCTGACCGGATAATTTGCCATTATTACTTAACTCCTTTTCTTTTCGGGAATATATCCTGAATACCGCCAAACAGCTTGCGAGCATCAGGATTACTGCAAACCATGTTCCTTCAACACCAAAGCCTGTGTTGTAGGTAGCACTGCTTCGCGCAGATGCTGCATCGAGTTTAAAGATAGAAAACTGAGCTGTAAATCCGCTGTTTGGGAGTCCAAATATAATGTTCTGAGTATAATTCCAAGCTGCATGTGCCGCCATTACGCAGTATATACCGCCTGTATAATATACAATCAAAGTAAAAAATATTCCGGCGATAAAAACATATATAATGGGCATCATCCCTGCTCCGGGGTTTAAAAGATGAAGTGCAGCAAAGAATATCGAGTTTGCTATTATCGCAACCAGAGGGTTCTTATATGAATGTCTTAGCTTTGCGTAGATGAAATTCCTGCAGAGAAGCTCTTCTGCAGATGACTGGATGAAAACAGCTATAAATACAGCGATAAGTTTTAATGGTTGAAAAGAGCTGTAGATAAGCGTTATATCTCCTCTTAATGTTGCCGCCATAACACAGACGGTATTTAATCCTGTGCCTATCATAAGTCCCGAAAGGATCTGCACTGATAATAATCTGACATTTTTTACGGTGAGTGCCTTTTTGGCGTACGGATCATGTTTTTCATACCACTTGTTGATGACCATCCAGATTCCAATAAAACTCGTGTACATCAAAAGCACGTTATAAAAGCCATCTGTATCATTTTTTAACGGGGCGTAGAAGATTATATCTGTCAGTATGATCCCTATAAGCTGGCCTATAAACATCAATATAAAAGCCGCAATCAGCACGATGGGAATGCTGTCTTTCCAGATATATTCATCTGTGTGAAATCTTTTCAT

Protein sequences of DBSCAN-SWA_1

>NC_014389|296861:345064|336668_340394_-|WP_013282991.1|DBSCAN-SWA
MLLYENYTKRNQITKSLRLELRPQGKTLRNIKELNLLEQDKAIYALLERLKPVIDEGIKDIARDTLKNCELSFEKLYEHFLSGDKKAYAKESERLKKEIVKTLIKNLPEGIGKISEINSAKYLNGVLYDFIDKTHKDSEEKQNILSDILETKGYLALFSKFLTSRITTLEQSMPKRVIENFEIYAANIPKMQDALERGAVSFAIEYESICSVDYYNQILSQEDIDSYNRLISGIMDEDGAKEKGINQTISEKNIKIKSEHLEEKPFRILKQLHKQILEEREKAFTIDHIDSDEEVVQVTKEAFEQTKEQWENIKKINGFYAKDPGDITLFIVVGPNQTHVLSQLIYGEHDRIRLLLEEYEKNTLEVLPRRTKSEKARYDKFVNAVPKKVAKESHTFDGLQKMTGDDRLFILYRDELARNYMRIKEAYGTFERDILKSRRGIKGNRDVQESLVSFYDELTKFRSALRIINSGNDEKADPIFYNTFDGIFEKANRTYKAENLCRNYVTKSPADDARIMASCLGTPARLRTHWWNGEENFAINDVAMIRRGDEYYYFVLTPDVKPVDLKTKDETDAQIFVQRKGAKSFLGLPKALFKCILEPYFESPEHKNDKNCVIEEYVSKPLTIDRRAYDIFKNGTFKKTNIGIDGLTEEKFKDDCRYLIDVYKEFIAVYTRYSCFNMSGLKRADEYNDIGEFFSDVDTRLCTMEWIPVSFERINDMVDKKEGLLFLVRSMFLYNRPRKPYERTFIQLFSDSNMEHTSMLLNSRAMIQYRAASLPRRVTHKKGSILVALRDSNGEHIPMHIREAIYKMKNNFDISSEDFIMAKAYLAEHDVAIKKANEDIIRNRRYTEDKFFLSLSYTKNADISARTLDYINDKVEEDTQDSRMAVIVTRNLKDLTYVAVVDEKNNVLEEKSLNEIDGVNYRELLKERTKIKYHDKTRLWQYDVSSKGLKEAYVELAVTQISKLATKYNAVVVVESMSSTFKDKFSFLDEQIFKAFEARLCARMSDLSFNTIKEGEAGSISNPIQVSNNNGNSYQDGVIYFLNNAYTRTLCPDTGFVDVFDKTRLITMQSKRQFFAKMKDIRIDDGEMLFTFNLEEYPTKRLLDRKEWTVKIAGDGSYFDKDKGEYVYVNDIVREQIIPALLEDKAVFDGNMAEKFLDKTAISGKSVELIYKWFANALYGIITKKDGEKIYRSPITGTEIDVSKNTTYNFGKKFMFKQEYRGDGDFLDAFLNYMQAQDIAV
>NC_014389|296861:345064|320896_321805_-|WP_013282976.1|DBSCAN-SWA
MKKKILCICLISAVLLSVFGCGDKESASDIQMENKIPEDLVSECCICNSINADGTLLLWGDRSDGDLFASYTIPSQPDVRIGDEVLLVYSESERAYAKYSDNRASRTFYMQNCHIFIEKITKENIKAAVPGTRKNKFLAQYGIGDGEEKENIDTQVQYSGDLQKQEQEPLQDIEYAKNIDHSVLEVRELIIDTSSVSDTGQIYDVVYERKGQVLSLIINEKQIKLQCDSKVIIGTIPYSITEEMYFGEVSDMPAIGDYLFYLNRADQMCLAEVIGIEYTPGEQCGLKIEELNIAEYITKDIG
>NC_014389|296861:345064|343632_344187_-|WP_013282998.1|DBSCAN-SWA
MANYPVSISLEEYQTACNKTIRIQLWATIACATVGFLIFSVVIYNIAGEFPVMKIGERELSSLWFIAFFFSLFTIMAVLEILRNRKEGYSPNRLKEFYANRTRVSGIYVESGAGKHHTQKVYEDSGEIYQVYAPVPFKYYSLKPLVCRAFLVGNTALVYEIIKELDQYKSSEEYVMEMRRKGRE
>NC_014389|296861:345064|343055_343241_-|WP_013282996.1|DBSCAN-SWA
MDEVNFWDIVDLAPATNKMRRNFRARKSALDQIETKGTVDEKNKVPDEMWDEFWDDEEIGA
>NC_014389|296861:345064|314859_315447_-|WP_013282965.1|DBSCAN-SWA
MEIMTCLAKGNEYRIEADAYRVNLEDNGEDTVVFDNLRLYENGAEGFGLGENFWGHHFDKEEAAASLIRAYINDNSSVRAIKVDKNLAKMMEKFFTFSGAHNSYQLDNGGMMINRPISKRYLDEKCILPLQLIDSEGNSYYSNGDAYALIRKDGTVATDMDFWYEQALEESIDAGNYKYICKELEDAIKERGLCG
>NC_014389|296861:345064|321820_322225_-|WP_013282977.1|DBSCAN-SWA
MIQVNYNNIQSVTPSDLLDYLHDTYDDCFSCKGSALTSSDLATMQGILGWCANVQAYLNPLICKMDIVCRSYPVSKAPDCDYQLALSKKTILTQYYKNIDNISKTVSRQCSLYQDQLQEMRYEQRADNIGRIAG
>NC_014389|296861:345064|315525_316071_-|WP_013282966.1|DBSCAN-SWA
MLNNSETKDALISVMNGLFKSIEAENNEKSAELIEELYKSYKERGDDYYQTSMHLEMMRLMELPARPFLMEHQEITGWDEFYIESIYNGLFSHWLRRTIDALEGSSCGGDKESFVTSSVVRSIVEKSNISLYVTYGDYGDKYKGRDNIDLNKQTFWSPSCFKDTDEVKEAFKRWWRVVEDK
>NC_014389|296861:345064|318783_319197_-|WP_013282971.1|DBSCAN-SWA
MATRRSNPYYPYRGRITGNKYRNEKIEVGGVKFDSKREARRYQELLLLEKAGEISELKTQERFILIPAQREPDTVGKRGGIKKGRVIERECIYVADFVYRDKEGNLVVEDTKGFRTKDYTIKRKLMLYVHGIQIQEL
>NC_014389|296861:345064|307920_311520_-|WP_013282961.1|DBSCAN-SWA
MKCKSLRFVALASAVVLSVSGMSTTAYAANRVMESTETAAVASSSEQASDKAETSEAAEGKADSQKNAVKEETAVKETSEQKKDDAKNAETPKTEVKKADSLTASEGAVKISVNAQMPEGSELTVTKLTPDRFAYQNIEAVMQKKDAGFDIAAVYDIAVYNGASVWEPAENNSAQITLNGILKSLDISADELVVYHMDDSEGTNTKKVDVKISEDNVTMNVEHFSPFVFGSASASQTAQNIATSFSATNGNNANVNALLGTSLTPDVSTGLEKFDFDIDAGTKTLTISLKSENTTAQLSENLTTAFASKLDQFTKVKIVPGTGKTITLKGSVFANLKKVTSIELGSGVSIVDNATSMFGGCKELVTITSADAIVLPATIKQMFKGDAKLTVLPSNFTFTANTADATEAFYNSGLTTLDLTSVNTIATQTKMLYHMENLTTLKTKAALSADSEWTGRWYKGAADDDARLASSWIGSSATENSVFHRLTTTQAYVNAGLDSMYHISGLGTANAYRIADEGKNKEFAAYCVNWNLDIPGQMGFYAASTVSNGSSWSTYLDTVGARLSGLDSTRVVERNLSNYNSDVQNALNTILFFGYPNDGAGIQDSKGYSNAEFYNATQLAIWNVLSGVLPSEGFSLGGLNTSDETKTLAAAGEILSKTYTDYTAVNGTVVSNDLTAYIPDASTQQVMVSGKASVRINKIDLASNGLLSGATLALKDEAGNTVDTWTTDTNTHVVKGLELGKNYTLSETAAPSNYDVTDAITFKAEGSYQLVKMNDGYSKHKIIVNKVDDSTSASPVTGAVLELTGKDYLGKDVTLTMTTPSTGKVEFEVLPGTYTIKETKVPSGYSKAEDIVITVKADDVDASKHVYSMVDPLAKYGSVAIIKYGNDGKTPLPGAVLKVVDSKGTEVDKWESTTAIHTIDNLVVGEKYKLVEVSAPEGYEKIKDVEFTVENGKTKSMSLTDPYKKHKLIIKKVDEGNNRVAGAKLKVTGKVLNGNAIEEIIFETSSDADKELSLLPGTYSVEETVVPEGYEKATKQSVTIEVKDDETKTVTLVDKKIKEPEKTEKKTETPGTVTILKYETGTTTPVNGAVLAIYNGDTKVAEFTTTNNAYTISTLTKGTTYTLKEITVPAGYVKAQDIQFTADGSAQTIIMYDAKAMVMGAKAPKTGDQTPIGLLMMLMAISFISLVGIGIFYTRKKIS
>NC_014389|296861:345064|306968_307805_-|WP_013282960.1|DBSCAN-SWA
MDTQHNGKRANIAKALLIALIPAISLIAALMFLIHYQKEYEIADNEYEQVADDYAKETSDIGSYIKVLAQENPGAKDSLDEKMHDATEGNLKKVDFLSLINENSDVTAWITVPFCSINYPVVQGPDNDKYLKTTYQGTANSAGAIFMDYTNNRSFNDMHTLVYGHNMKNNSMFGGLKKIRDNPEAAKEDPYFYIYLPDGHMRQYEIFSARVIHADDPCYRFFDGMDEYHRFVNECLSGSKSKWNVNSDLSSGLPIVTLSTCSGDNDRFVVHGILHAIY
>NC_014389|296861:345064|305727_306960_-|WP_081441833.1|DBSCAN-SWA
MKMNLRRKTKNALTGILIAGVIVSTAACGTASENRVAVNDVFLNDYRNMEITTTLKEATEDDVKEELEHIAKDYNYVVPIDKAVSSDSTVDISLTKKNADGSIDEASTLTATIVLGNDSVPAELEEAVIGLSKGETKEFESTDSSGEKTPYVVEVVTVYEYGEITDDIAGGLGIDGVTDLESLKKYLIDALNRDNKDIYKNELKTEISNTLYNNCKVNNIQEHLKNEYYDILYKQLTDLVEYYSDTSEEEVTLYDLVSPTMEKEGYVGTTEDYIAYCAERNAKLYLIYKAIAEKESISVDDIDAYSLAATDWASQTSEYDTLKDFISDNSFESYERDALADAVMDYLVNLYAGDIFKDDSSDAPGEISQDENSLDEALEEASNELSFEEKTEETQPEEVSGAAASSQTSN
>NC_014389|296861:345064|319793_320099_-|WP_013282973.1|DBSCAN-SWA
MNRIVNTEYAMFVTNKESGDEFLCAGPFETSIAVKRAYEKKLKDEDFKKMIVPETAHVCTREIVISQGLWEPYDDHVASDTELILGVKASTLPGKGGGLFE
>NC_014389|296861:345064|304910_305078_-|WP_154649898.1|DBSCAN-SWA
MEKGALENPVKSYLDSIKDKPLRTCHGLTPEAKKRKIKMFDFFMEFIEDNPEKQE
>NC_014389|296861:345064|303304_304069_-|WP_013282955.1|DBSCAN-SWA
MKRMIKCFALSVVLALALRAYLAMGTQVVETTVKNAQEVQGSIFSARQVTYGITNSVKLAVSQISLDAKAGEREVIDVPASVKDVDFTKTDAVAWIYIPSINLSYPVYQGEDNEYFLKHTAEGKRSSHGEIFMNASNNSDFSDENTIIFGHNMKDRTMFGTLKNVNIEDYIWVVTKDHTYTYQIFSTYSATEKSSMFVTFDKGQHNAYVEKALDKSTQKSDVNTDGRILTLVTCQGIAHSGQRLFVHGSLVQTL
>NC_014389|296861:345064|323151_323430_+|WP_013282979.1|DBSCAN-SWA
MDVPCYTTLVLQKPFPITLVVVVHIAKQNGKIIFESSCRLNTDTREIVGVKKDVIPADFDEEFVQLSLNGVTCPAGKRSDINPEETDSFWYE
>NC_014389|296861:345064|316840_317314_-|WP_013282968.1|DBSCAN-SWA
MNVQLHGKSSRYICFAIGALLLLLSLIGFSRQSSVKEDQAKVVKIVKISENRETVRNGNDGGIDKLITYDAVCDIETLGLSTEHPEQTRIVVNRRFEDNLPNEGDVIKVSKHNGEWSEHQPKHAFIGNFLMMLIGGFMIWGGVVGKIEDKNKEISNI
>NC_014389|296861:345064|302099_302381_-|WP_013282953.1|DBSCAN-SWA
MKFAFQDQVSFTDTKSFDKYVASWRIERMKYIVFFIGGIRKVEIPADVEKRTRELVSLGYPVYQFSEDGYKNLLAEDNAATVAEKANKVIFAM
>NC_014389|296861:345064|312254_312869_-|WP_013282963.1|DBSCAN-SWA
MKKKLLHLIALLLLCSTIAITAHADFSLPDGSRFDPDYYANANPDVVAAVGDTPSVLAEHYWNNGIQEGRLPYAGAKDVSAASLVRCVNEYRLQNGLPALTVDSAVQAEAQLRAKEMASSGVFSHTRPNGEKWQTAFGNNWNKTYSKLGENLARGQSSSERAVSAWKKSPGHNEVLLKDGVTCIGAGVAKGNDGKFYFVITVVN
>NC_014389|296861:345064|332417_333575_-|WP_013282988.1|DBSCAN-SWA
MKCCDHLGNPFSSQAAMCKCYGINQSTFVTRIKCGYSLEYALTHPASPSNAASILCMDHLGNEYESFKKMCEAYGHNDNTVRCRLRKGWALDVALTTPLFKDMYIYKGEKYSLKRLAQIYGVPYTRLVQRIRYGFTLEEALTIQNGHDRHSVKVAADGKVLYGSLKQFLKETGISTAYFYRQRKKGIPLEQILSDYRSKEKRCAENRKIKTICETYSISYETIKKRLEHGLSLEEALAAKNPLFKSCKDPFGNHYDTFKAMCSAYGQSDNAVRNRIKDGMTLLEALTVKPFQYIVDDKVYKTIKEASDTYGTCYATTRIRLKEGYSLEEAILIPSHWKWQNLKEKFSFNGEKYYSYKCDACGVQYMFTKPEIRAHTLMHIKNKDI
>NC_014389|296861:345064|317329_318472_-|WP_013282969.1|DBSCAN-SWA
MNKSNVMELKKTLKITTEFMPSIDRICTCFVNGNKEKLISNTESYSSLGDEEQFKYIDILKAALSGTIDKKLLNLEFGSNEASIKAEGFMTEAYTEVFKSEEKRDELFDTIIENYIFDENYLIVAGHGVYDVPMKASDGAILEDETTTYEFMLVAICPVHSTKAGLTLDSDSGRMVSSRQVQIVQAPVHGFLYPAFNDRDTDLHSMLYFTKKPEDSHPELIEKLLGIPAPTSSVDQQHIFESIIAEVTDDKADFEVIKTLHENLKEMEETAQYNGEIKTLHKEEIKEILVSAGVKEEKLDDFEHIYERAGGNDDTEFKTGNLIELDKFAVKSSDVEIKIKPDRTNLVQQRKIDGRNCIVVALEGDVRLNGIQINAPASQL
>NC_014389|296861:345064|329647_330076_-|WP_013282985.1|transposase|DBSCAN-SWA
MDKYSIFTINSDVTHGRGYVYCLQYHIVWCTKYRKKVIIGNIESDVKEHLYRTAEDLGIKILAMETMPDHIHMLIECKPQCRISDAIKVFKGNTARWLFLTHPEIKTKLWGGHLWNPSYFVATVSERTKEQVTNYISSQKEK
>NC_014389|296861:345064|335074_335758_-|WP_013282990.1|DBSCAN-SWA
MPKYHDHLGNEFASKEDMCRYYGINSTTFFNRLKAGMTLEEALTSPNLYSCTDHKGIFYKSKSEMVNTYGLKYSLFTHRLRKGWTLEETLEISPEIILLRGKWPSFSLNGEDYYTYKCPTCNNQFVFTPAECRQHYLRHKYSGEINETLYTKTPIRKLETVTDHNNNEYSSLRAMAKKYCIAVSTLKARIRRGWSLEKALTTPPDKTCIRAKRTLNAQNKIQGSSGK
>NC_014389|296861:345064|325383_327063_-|WP_013282982.1|DBSCAN-SWA
MSTDILEAVRNRTKEDLKNKLSLFNRCAVPRCTGFGKTWLLSEIAQEYDTVLYLYPAEIIKKTAMHAIDETWEIEDEDESEAEEKKAIYDELGYELDYHNIRFMTYTKLARMDKKQIKELPLYSLIIMDEAHRLGGELTKTRALWLMYYQKNSHIIGATATPERMDAFDVIAEFFRGICVFQYTLHDAIQDGIIKMPIYIYCTYDIETSFKQAARLTGQDKNNIVVDEVLKSRLFEVSNVHNIPKIMKKTTDKYVSAKSYMKYIVFFPNIKKLLERYTKVEEWFKEAFPGYTVNTLVVTSENKTTQNNINNLNLKHHRKTIDLIACVDMLNMGYHVEDLTGIVMYRCTTSSQIYIQQFGRALSTGSKNRCVVFDIVDNLHRKSLFHLAPEGKRRIKRAHPTKKERAERLLDEIKHELTKKEQILMRKFIEDELEAEDQVAFDALWKKVNEISEEDIYAVDHLATYRELIAKTIAEVKYTRSKRAAEEYFRIQTSKCKRQIPNTVNELKKMKDLTPALKIFLDWQKIDEEDMLEYILEPGSVDKIDVKKIKQGIRDSMAY
>NC_014389|296861:345064|302517_303024_+|WP_013282954.1|DBSCAN-SWA
MDTQRLLQKINIKDANGMDTRDDTLQLISDAIDKMTPQDVIEYKEHSINADQLFEKYYPKLSPIPASAIQQIISKIPDIIADYEKAADERGEYLYQLLFAGIAAEIFNQNDKSPVFDGDVDSFSVIPDDYTAWKEKIIALLKEFTQSANGAILLEITLFLGIIPNKKS
>NC_014389|296861:345064|333777_335112_-|WP_013282989.1|DBSCAN-SWA
MLKIKFKDHLGNEYETRAEMAREYGLKPTTLEARLKRMNIEKALVTPVKEHCKGECFDHLGNIYPSENAMCKYYGIHPATFRDRIKNGWPLEKALSQQNYSVKIKCRDHLGNEFESKEAMCRYHGVNAETFRDRIKHGYSLEDALCPKKIADTNIYIDHLGNKFRSVKEMCNKYGVEVKTYQWRLRQGRSIKEALSSENNSCQKLRDHKGKEFKSLNALCRYYNVEPTIVKRQLDKNIPIKEAIKHAKCVKEHCYKDHLGNIYPTLNKMCKAYGITVGIYESRISRGVSLEDALTRPKRSHKVHDHNGCEFASLHAMCEHYGLGLESYIRRRNLGWDLEDALLTPVIHKEHKRYKDYKEKEYNSLKDMANAYGIKANVLSCRLRSNWPLKDALLLPDIRQNKIVVAFKVEDERYYFYKCSFCHEEHIYTATEINIHHHKHTQMR
>NC_014389|296861:345064|322237_322480_-|WP_013282978.1|DBSCAN-SWA
MKQGRVGMNIKRCDYCGVYSMKPVSITFGSRAKRLTNAASGKNFGLSAHSPEKTACLCEDCYKKLGESMLQELDQEKEAV
>NC_014389|296861:345064|323821_324742_-|WP_013282981.1|DBSCAN-SWA
MDKMVKKVEELAKKFAERLAEEGYYPDIRPGYKLNMGPEALAITCKKNKDDRIAPTISITKDHVLAIENGRTTEEDYFVEGIEIFRNAFESEQYKNSSSVARAIEKFENRDDFLEGIAAFIYNHNVNKNPGFVHKKLNDELSVMVRYLVPEAEGSIPITKAQLEHIGVTEKELFETAIKNSPVINPPRIVSMNDILRQKGCWMPVDLRGLEKFLVINTVNCEQGAVAILYNGVADAIRERLGEDFFIIPSSLNEVIVLPISMLEERKVDDLKAMIMDVNKTVLPSTEYLSDRPYVIRDGRLEELAG
>NC_014389|296861:345064|313325_314576_-|WP_013282964.1|transposase|DBSCAN-SWA
MYLTVKQQVKHLSKDDYCSIRELCHSAKNLTNEAIYNVRQYYFTEGKFLKYEKNYVLLKNSPNYKALNSNMAQQILKEVDGSFKSFFGLLKLAKQGKYAFKDCKLPNYLSKDGYATLVIGFVRLNDNKLILPFSNSFKKTHKPVEITIPPVLLDKKVKEIRIIPKAHARFFEIQYTYETECIQRNLNKNNALALDFGINNLVTAVSNTGKSFIIDGRKLKSINQWFNKENARLQSIKDKQHFGKKTTNRQKAINRNRNNKVNDYMSKAARKVIDYCITNDIGTLVAGYNVTFQRNSHIGKQNNQSFVNIPYGLLRDKLSCLCELNGITYVEQEESYTSKASFWDKDCIPVYNNDNPKEYQFSGSRIHRGMYKTANGFKFNADVNGALNIMRKSSVVDLSILYGRGDVDTPIRIRIA
>NC_014389|296861:345064|305500_305710_-|WP_013282958.1|DBSCAN-SWA
MVSVEKIEYMRHEISCGEITLKAAIEKCDLKEAKELVKRLAIEDNLSYKEYDEAIILLEEKKWPKKAKS
>NC_014389|296861:345064|304199_304391_+|WP_042258598.1|DBSCAN-SWA
MLFNYEIVDIGGCRYQVGVGVIINTKTQVSFLKPGTTYFANICIENNEVVANTGLRDDEIFSI
>NC_014389|296861:345064|296861_298214_+|WP_013282947.1|transposase|DBSCAN-SWA
MGVDNTKPDIRELLNIVISDVSGRITEYCEHPGRDFTRTRKLPADILMHLMLNMAGNSLNKEIYDHFPDKKQRMSASAYEQQREKLKPDAFKAMLSVLNNSFTDAKTMNGLRVYGIDGSDFCTPLNKDSKWYIPNHYIRKDGQEAKGTCLLHGNFLYDLLNKQYMDVNETRDEREGAVGLIDGISDTGHSLVIMDRGYSGFNMIEHCNRYGGYYVIRHPLTNTIKEISELPDESCDKYIEVKVSTNSQQWCDIYGYRKLGVRKNKKISKLYSDNTKATQWDFEVKCIVKFRVVKFKINDPDTGKQVWEVLVTNLPRDKFDLKTMKRIYWLRWNIETSFKELKYALGAINFHSKKDKFILQELYAHLIMFNATARVAAHIPVEYSEKGYTYAVDFKMVVYIFRKYFRPFSKDPPEDMYADMKQYRHMLKDGKHNIRLLKPKSAVYFTYRVA
>NC_014389|296861:345064|340618_341509_+|WP_013282992.1|DBSCAN-SWA
MITKEDIVKALSEEGYEVRLVTKHKNHKTKEGITIRQNEEMTAPTLYMDEIPLDKYTDLKELISDIKDFLSRQSTRGDDLKKLAENIDDYNTVKDKLYIEIVSATDNEEFLSSMPHRKVLDFEVIFKLKLSDYAVASVSNALLEAWGVDIETLFNDAMASSEKNMPYGICHVSDVIPKPLTSSFINVPMYIVFRPDDENGAAAILYPEFQEFVGKQIGGFYILPSSIHECIMVPDAFYQLGGASEDVPGALKEMVSLVNKECVPKEDLLSDNAYHYDPNRKVLEFADEYFKNIKDA
>NC_014389|296861:345064|342548_343022_-|WP_013282995.1|DBSCAN-SWA
MEMKKAIRCIDQTYVEGNAKELVDKAYRYDDDFSDDAVQEIIDFATAQKEDCRTLIYLLEARQEEKEGKLLLGQIKNDILLYDSAEEFEYNDDTVEIWKESTTGQVLVHITGEDKQGPYHATNAYDFEEFMNRDMGSLESLIGETLFYGTVYDEEVA
>NC_014389|296861:345064|343401_343620_-|WP_013282997.1|DBSCAN-SWA
MDQKKLFYNMCMDLWALGKELDKPRVDMTDEDWTRAIGKMDELTVKYKALGVREHDLISKLMMSILDYVENS
>NC_014389|296861:345064|298414_299182_-|WP_013282948.1|DBSCAN-SWA
MEYAEWKEEIKEVPIEDCCEMLGIEYRRQGSLLSILCPNPAHNDQHYGSCFIKNGRYTCYACGDHGDNIKLVQNVKMMSYQEATHMIARYANIPSWDDISYQQDEKEPLPLTDKQLKLLGLSSRVTIQHINGLEDVRPENGSWIRDLEGYATYIPETVNLVDLYREDKDLFNEMVIGKLFYRLIDLLTYYLTETFSSVKEQEATEMEIEGLIPLAYRYQKVCKKYGYDLGFVKEYKKKTITRIQTRSLSKFKFAV
>NC_014389|296861:345064|320574_320760_-|WP_013282975.1|DBSCAN-SWA
MEEVVLKFVEFFSRAILAVVGIWAGFCVAGICGSVILTFACFMCLHISADQTHGLEVKEVL
>NC_014389|296861:345064|299536_300247_-|WP_013282950.1|DBSCAN-SWA
MKGRRGRIIAFLLIAVIVGAVLRSITAAAGEIKELDEAALYKTEMAKEENEKEYARGDDILVNTEELVDDSFASNEDGANEDYTQDASEATYFSLGEDKSEAKSEYMDNTPGDTTGSDNNCMEVLKLINDKRAEQGMPALSWSDALTSAASVRAKEASESWSHTRPDGTEFWTVDPDVQYAENLAKQYFNAESVFNAWMESPTHRDNIMNAEYQTIGMAIYYTEDDMIFWAQEFGY
>NC_014389|296861:345064|311681_312182_-|WP_143754404.1|DBSCAN-SWA
MMKKMAVMVMTMVTVMAMGMTMSFSSEAKGAEIDDDLEIVVETPADPEPEVPEIPEEPTPEPEPIPEPEPEPVPEPEPEPIPVPQPEPTPEPEYQPETVETYYEEVVEEEVVVAPVVIEEEEEGEVLGDYIEVPETGDLGFCLLMAAAILVGLFVLKTMIRLVRLF
>NC_014389|296861:345064|328321_329644_-|WP_013282984.1|transposase|DBSCAN-SWA
MKIYSTYSVKIKQYNHIFSETVTIYRDAVNFLMDVCLAEWDLVSVIKGNQAQMMHVESLCHKTKENSSPKYDFDSRFYKMPSYIRRAAISEAIGKVSSYKSNLANWKLNPNGKKPTLNNCGYVYPSLYRIGMYNLADDYSAQIKIYHNNTWNWLSINLRKSDMDYIYHRCNGRKMCAPTLQKRGKEWFLDFPFEEKATLTDTNSLVVGVDLGLNSACTCCIMDSKGTIYGRRFLRLPRETDRLNHAVNRIKKAQQYGNRKMPRLWAKAKGINDDIAVKTANFIIDTAVMYNADTIVFEHLDLAGKKRGSKKQKLHMWKAKYVQSMVTDKAHRLSMRISHICAWGTSRLAFDGSGRVLRGKDADMPTYSLCRFQNGKTYNCDLNASYNIAARYYIREIFKSCSVTDRLDIEAKVPQCSKRSTCTLADLISLNAVLDNILVA
>NC_014389|296861:345064|299185_299359_-|WP_013282949.1|DBSCAN-SWA
MTKEKKQKMELIKGAAGMSRACIDFTSVKSGRIFEDRRYKAKNDFGKNQIRDYMKEM
>NC_014389|296861:345064|344155_345064_-|WP_013282999.1|protease|DBSCAN-SWA
MKRFHTDEYIWKDSIPIVLIAAFILMFIGQLIGIILTDIIFYAPLKNDTDGFYNVLLMYTSFIGIWMVINKWYEKHDPYAKKALTVKNVRLLSVQILSGLMIGTGLNTVCVMAATLRGDITLIYSSFQPLKLIAVFIAVFIQSSAEELLCRNFIYAKLRHSYKNPLVAIIANSIFFAALHLLNPGAGMMPIIYVFIAGIFFTLIVYYTGGIYCVMAAHAAWNYTQNIIFGLPNSGFTAQFSIFKLDAASARSSATYNTGFGVEGTWFAVILMLASCLAVFRIYSRKEKELSNNGKLSGQHQP
>NC_014389|296861:345064|303027_303285_-|WP_042258596.1|DBSCAN-SWA
MGDLQIVTGYRFDLKTADAKLSNAECYLLLTTFKYSAPRGKEKEAVSKILVISQRRGIAKQYCKGTTFVGFENYLDYLKKRARVS
>NC_014389|296861:345064|301857_302079_-|WP_013282952.1|DBSCAN-SWA
MDKNKRERERTELDKYLVVKAKEDRELHEAADKLIETVIRISNNYNEVLESKMERVLFYNTSARKPIGLQTVG
>NC_014389|296861:345064|331143_331356_-|WP_042258606.1|DBSCAN-SWA
MTNTKVTVHLGNNYSSVKEMCKYYGIDASKMHIYPRREYSFEKALTIPKKKSLKNKAIDKCIAFLYRLRG
>NC_014389|296861:345064|316080_316713_-|WP_013282967.1|DBSCAN-SWA
MIYILIGKSASGKDRALNRIIDGKPVKGIDIKDRCLPIITCTTRPMRVGEVNGKDYHFITKELFKRMASSGEMLEWRCYHTLVQGKADDWYYGTPWTSVQNFESQDYIAIVDCEGAKAYIDACGKENCKVFYIYASDEVRKERAMKRGSFDETEWNRRLRDDEEKFGEEALSEIRKELGENFVWVDNNTNSDNVTNFISIFQMDEIVARA
>NC_014389|296861:345064|327052_328204_-|WP_013282983.1|DBSCAN-SWA
MENGWSLQDALMIKPVHKVFKDHFGRKFETATDMCRYHGVSYSLYLNRLKSGKSLEEALNPHNKEKYIDHLGNVFNTQKEMCAFHGVSENTYYQRLRAGKTIEEALCKAAIYYKKDSDGKIFCRTKKEKQTLKREWFDHLGNKFSTLDEMCAFHGVERHAFTRDIKKCVSLKEALTPKVSVKVRCTDHLGNEFESITEMCKHHGITLSQYESRKRSDWPLERILSKGDYARRKTCTDHLGNVFESEIKMCQHWGVSDKTYRHRIIYDGWSLEKALTTKDIYTCTDHLGNVYKSKVEMAEHWGQKKGVIKDRLKLGWGIREALIIPNNTSKVYSTSGKKVLFEIDGISYYAFKCPCCNNEYAFTKEEIRSHYANHFEKGDMNEH
>NC_014389|296861:345064|305201_305414_-|WP_013282957.1|DBSCAN-SWA
MVPYKNFNVEANTRIKYPKIFTMEIYKNNDFNIVLAQQFLQHSSVVTTQRYIGITSEMQEKALLGHIQIL
>NC_014389|296861:345064|331352_332255_-|WP_013282987.1|DBSCAN-SWA
MPKCLDHLGTEYGSKKERARAYGLGNTTVDERLSAGWSLEEALTTPSNHGNKRRVGCKDHRGKSYPSFRAMARAYGLEKSTLKERLDRGWSLKDALITPPDKTRITFDEEKAKENGISKSTYKSRLRRGWDEDAALSIKVGDAPYEALKEGEYCTDHLGKVYRSYKKRAEAYGQKVDVVWHRLEYGWCLEKALTVKDGRRVFCTDHKENKYKSITEMCDTYGIKRDVYIKRIESGYTQEEALLIPTGKEFLCKHHGKAFEMDGIMYYYCECPICKEEHVFTEAEMRSHTLMHVKNKEVRL
>NC_014389|296861:345064|300485_301736_-|WP_013282951.1|transposase|DBSCAN-SWA
MYLTVKQQVKHLSKDDYKSVRELCHAAKNLTNEAIYNVRQYYFTEGEFLKYEKNYTLLKTSPNYRTLNSNMAQQILKEVDGSFKSFFGLLKLAKQGKYSFKDCKLPHYLPKDGFTTLVIGFVRHNGNRLILPFSNSFKKTHKAVEITIPPMLIDKKIKEIRVIPKAKARFFEIQYTYEVECTQRNLNKNNSLALDLGINNLVTAVSNTGRSFIIDGKRLKSINQWFNKENARLQSIKDKQHFGKEATNRQKAIVRDRNNKVNDYMNKAARKVIDYCISNDIGTLVVGYNETFQRDSNIGKRNNQTFVNIPYGKLRDKLEYLCELNGITFIKQEESYTSKASFWDKDVIPVYNNDNPKEYMFSGKRIYRGQYRTSSGKTLNADVNGALNILRKSSVVSLEALYSRGEVDTPVRIRIA
>NC_014389|296861:345064|330138_331092_-|WP_013282986.1|DBSCAN-SWA
MAAHYNLRSDTLQNRLKNNWPLKKALLTPAGCKSQCTDHLGQVYANQSEMCKAHHIAFCTYKKNIQNGMSLKDALTSKKDTTVFDHLGNSYPSQTAMCMAYGINQWTFLDRIERGDSLEDALTRPLKTYFCTDHLGKTYKSRSAMARAYGIDPDILSDRLNEQKWSLEKALTTPVGAPREELKVKDHLGNEYLSIKEMAKAYKIPLKCLEYRLRNKMPLEEALMLPVDHGNAGSKPCKDHLGNEFKSMVAMARYYGKSPKAISACIKSGGNLKKLLAEDRIAEYTDHLGNIFASKSAMLKHYQIAQGTFDNIGGAHS
>NC_014389|296861:345064|323483_323804_-|WP_013282980.1|DBSCAN-SWA
MKIEFYDTITEMNSCNMALAKVSKEDLKKIFEDAGKVPKNDCLEEDDSYIFGEIQFMFSKDMSSLDEILVFPVYGDDEGGEVNGDFINAPDSFTSFGKEAREYLVK
>NC_014389|296861:345064|342043_342256_-|WP_013282993.1|DBSCAN-SWA
MKRLWKQGDRFKIDTDIDGVRACTQGTVEADQKKGDKKLLCTLDYVDGEGNVGVRVKIKDMYPVATDAAV
>NC_014389|296861:345064|342275_342536_-|WP_013282994.1|DBSCAN-SWA
MARRIEYPNPDIKCAWCGRDIGSDSRFYFKYKGKAFCSRYNKNSDLENICLKNYLVEEMGAEITEEEVDREPEYIMDEEVLYGLGA
>NC_014389|296861:345064|319321_319663_-|WP_013282972.1|DBSCAN-SWA
MGKNEMITIPKKVVHQAAAALVLAVVTGTILFNSHSQGIKAYDGGAEPVISTEARVGFEEGKLSKSAAVKKINKRLSELVITGEIEKWNYNEDTGEYNIVFSNGTKFGYTLTR
>NC_014389|296861:345064|320052_320574_-|WP_042258603.1|DBSCAN-SWA
MASGKAHLAAGVAMTGLLAAAGGCTGNEAMVMIEGAVIGSLIPDIDNKTSTIGKPLFILRPFQGTYDHRSRLPHTFLGCLMFTSIVAVLSSFDPLLVGGFLFGYILHLFVDSYTKQGIRWLYPISKKYYGACKCDMSSPFKRLYKRFVKACDEMEGVKNEQDREHRVCNVCHE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013282947.1|296861_298214_+|transposase	IS4 family transposase	NA	NA	NA	NA
WP_013282948.1|298414_299182_-	hypothetical protein	NA	NA	NA	NA
WP_013282949.1|299185_299359_-	hypothetical protein	NA	NA	NA	NA
WP_013282950.1|299536_300247_-	CAP domain-containing protein	NA	NA	NA	NA
WP_013282951.1|300485_301736_-|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	4.8e-66	39.2
WP_013282952.1|301857_302079_-	hypothetical protein	NA	NA	NA	NA
WP_013282953.1|302099_302381_-	hypothetical protein	NA	NA	NA	NA
WP_013282954.1|302517_303024_+	hypothetical protein	NA	NA	NA	NA
WP_042258596.1|303027_303285_-	hypothetical protein	NA	NA	NA	NA
WP_013282955.1|303304_304069_-	class B sortase	NA	NA	NA	NA
WP_042258598.1|304199_304391_+	hypothetical protein	NA	NA	NA	NA
WP_154649898.1|304910_305078_-	hypothetical protein	NA	NA	NA	NA
WP_013282957.1|305201_305414_-	hypothetical protein	NA	NA	NA	NA
WP_013282958.1|305500_305710_-	hypothetical protein	NA	NA	NA	NA
WP_081441833.1|305727_306960_-	hypothetical protein	NA	NA	NA	NA
WP_013282960.1|306968_307805_-	class B sortase	NA	NA	NA	NA
WP_013282961.1|307920_311520_-	Cys-Gln thioester bond-forming surface protein	NA	NA	NA	NA
WP_143754404.1|311681_312182_-	hypothetical protein	NA	NA	NA	NA
WP_013282963.1|312254_312869_-	CAP domain-containing protein	NA	NA	NA	NA
WP_013282964.1|313325_314576_-|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWW3	Bacteriophage	1.7e-68	39.8
WP_013282965.1|314859_315447_-	hypothetical protein	NA	NA	NA	NA
WP_013282966.1|315525_316071_-	hypothetical protein	NA	NA	NA	NA
WP_013282967.1|316080_316713_-	guanylate kinase	A0A0K2FM14	Brevibacillus_phage	8.1e-14	34.3
WP_013282968.1|316840_317314_-	hypothetical protein	NA	NA	NA	NA
WP_013282969.1|317329_318472_-	DUF4317 domain-containing protein	NA	NA	NA	NA
WP_013282971.1|318783_319197_-	DUF1064 domain-containing protein	Q6JIF9	Burkholderia_virus	2.7e-18	49.2
WP_013282972.1|319321_319663_-	hypothetical protein	NA	NA	NA	NA
WP_013282973.1|319793_320099_-	hypothetical protein	NA	NA	NA	NA
WP_042258603.1|320052_320574_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_013282975.1|320574_320760_-	hypothetical protein	NA	NA	NA	NA
WP_013282976.1|320896_321805_-	hypothetical protein	NA	NA	NA	NA
WP_013282977.1|321820_322225_-	hypothetical protein	NA	NA	NA	NA
WP_013282978.1|322237_322480_-	hypothetical protein	NA	NA	NA	NA
WP_013282979.1|323151_323430_+	hypothetical protein	NA	NA	NA	NA
WP_013282980.1|323483_323804_-	hypothetical protein	NA	NA	NA	NA
WP_013282981.1|323821_324742_-	hypothetical protein	NA	NA	NA	NA
WP_013282982.1|325383_327063_-	DEAD/DEAH box helicase family protein	H9C0Z2	Vibrio_phage	4.4e-06	26.2
WP_013282983.1|327052_328204_-	hypothetical protein	NA	NA	NA	NA
WP_013282984.1|328321_329644_-|transposase	transposase	NA	NA	NA	NA
WP_013282985.1|329647_330076_-|transposase	IS200/IS605 family transposase	A0A0H3UZM0	Geobacillus_virus	7.4e-27	43.5
WP_013282986.1|330138_331092_-	hypothetical protein	NA	NA	NA	NA
WP_042258606.1|331143_331356_-	hypothetical protein	NA	NA	NA	NA
WP_013282987.1|331352_332255_-	hypothetical protein	NA	NA	NA	NA
WP_013282988.1|332417_333575_-	hypothetical protein	NA	NA	NA	NA
WP_013282989.1|333777_335112_-	hypothetical protein	NA	NA	NA	NA
WP_013282990.1|335074_335758_-	hypothetical protein	NA	NA	NA	NA
WP_013282991.1|336668_340394_-	type V CRISPR-associated protein Cas12a/Cpf1	NA	NA	NA	NA
WP_013282992.1|340618_341509_+	hypothetical protein	NA	NA	NA	NA
WP_013282993.1|342043_342256_-	hypothetical protein	NA	NA	NA	NA
WP_013282994.1|342275_342536_-	hypothetical protein	NA	NA	NA	NA
WP_013282995.1|342548_343022_-	hypothetical protein	NA	NA	NA	NA
WP_013282996.1|343055_343241_-	hypothetical protein	NA	NA	NA	NA
WP_013282997.1|343401_343620_-	hypothetical protein	NA	NA	NA	NA
WP_013282998.1|343632_344187_-	hypothetical protein	NA	NA	NA	NA
WP_013282999.1|344155_345064_-|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

3. NC_014388

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	71646 : 111667	33	Tupanvirus(14.29%)	protease,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_014388|71646:111667|DBSCAN-SWA
AATGAAAAGACTAAAGGTAACATTTAACTCGCCAGTGGTTCTGGGGTTTATATTTATTAGCTTTGGAGTTTTAGCACTGGGATTCCTGACAGGAAATCTCAGTAACCAGCTTCTTTTTATGACGTATCATTCTTCGCTTACAAATCCATTAACATACGTAAGATTTTTTACACATGTCTTTGGCCATAATGGGTGGGAACATTATATTGGTAACGCTGCATATATTCTTTTGTTGGGACCAATGCTGGAGGAAAAGTATGGTTCTAAGAGGATTATGCAGGTAATCGTGATCACCGCCATGGTTACAGGGCTCGTAAATTACATATTATTCTGGAATGTAGCGCTTTGCGGTGCAAGTGGTGTTGTATTTGCATTTATCCTGCTTACTTCCTTTACAAGTTTTAAAAATGGTGAGATTCCTTTGACTTTTATACTTGTGGCGATTATCTTCATTGGACAACAAATATACGATGGATTATTTCTTCAGGATGATATTTCGAATCTTTCACATATCCTCGGAGGCGTTATCGGTGCAGTTGTCGGATATAGGCTGAATAAGAAATAATACCTGTTGCTAGATAAGAAGTTTAAAGAGGTAGCGGAGAGATGAACAATAGTTTTAATCATATTTCTGATATGGAGAATATTTTCGACGAAGTTTTGGATGCACAGTACCTCATAGAGAACGCGTTAAAAGAGTATAGAAACTTACAGAATAAAGTCAGAATGATTGAGGATTATTATAGCAGCAAACAGTGGATAAAAGATTTTGAGATGGATGAAAGAGGAGAGATTCCACCGGAAGTGAAACGTGGAGTACTTTCTGAAGATGGAATTTATAGAATGCTTGAGCGGAATAAGGAAATTATGAAAATGATTGGGGATGATTAGTAGCTAATTTGCAGAACTAGCGAGAAATTCACATAGAAAACACATATATAGTAGTATATTTGTCATACAATTTGTAATACAATGTGTTATAAGAAAAAATATGGAGGACAAATATATGGGACTTATATGGGGACTTATACTTGGAGCTATCGCTGGACTTATTGCAAGTAAGCTGATGAATGAGAACTCAGGATTGATTAAAAATATTCTTCTTGGAGTTGGAGGCGGTTTTGTAGGCGGTTTGGTATTTAAGCTTATAGGATTTGCTGCTACAGGACTGATTGGAAGCCTGATTGTATCTATAGTTGGAGCTTGCATTTGTATCTGGGCTGGAAGAAAGCTTTTTAAGTAAATAAAAATTTACAGGATTCCCCTGGCTATGTGGAGCCAGGGGTTTTTTATGATACAGGAAATTTCTCCGTTACTAATGCGTAGAAGAAATAAAAATTTCATTGAATAAAAACTGGATTATTGTGGCATAGAAGAGCTTATAAAACAAAAAAATAAAAAAATTTTTTATTCTTTTAATAATTATCTCAAACGCAGTATTTATGGGCGTTTCGGATTTGCATTTATCGTCATTTCGATGGTTATGGCTTTGAGAAAACGAGAATTTAAAAAAATCTCAAAAAAAGGGTGTTGACACTTCATTTGCACTATGATAATCTAACCAAGCTGCTTGTGAGGGCAGCGACACAGAACCTTGACAAATAAACAGTAATGCAACCCTGAAAAATTCCAAGAGAATTATTCAGAACAAGAATTAGTAAATAACGGACAGAACAAAAGCCAAGCTTAGTTCTAGCCTGATCAAACTTTTAAACGTGAGAGTTCGATCCTGGCTCAGGATGAACGCTGGCGGCGTGCCTAACACATGCAAGTCGAACGGAGATATAACGCTGCAGAGACTTCGGTCAAAGCTTGTTGTATCTTAGTGGCGGACGGGTGAGTAACGCGTGGGCAACCTGCCTCATACTGGGGGATAACAGTTGGAAACGGCTGTTAATACCGCATAAGCGCACAGAGTCGCATGACTCAGTGTGAAAAACTCCGGTGGTATGAGATGGGCCCGCGTCAGATTAGCCAGTTGGCGGGGTAACGGCCCACCAAAGCAACGATCTGTAGCCGGACTGAGAGGTCGGACGGCCACATTGGGACTGAGACACGGCCCAAACTCCTACGGGAGGCAGCAGTGGGGGATATTGCACAATGGAGGAAACTCTGATGCAGCGACGCCGCGTGAGTGAAGAAGTATTTCGGTATGTAAAGCTCTATCAGCAGGGAAGAAAGGCTCGCAAGAGAGATGACGGTACCTGACTAAGAAGCCCCGGCTAACTACGTGCCAGCAGCCGCGGTAATACGTAGGGGGCAAGCGTTATCCGGATTTACTGGGTGTAAAGGGAGCGCAGACGGTCAAGCAAGTCTGAAGTGAAACCCCACGGCTCAACCGTGGGCTTGCTTTGGAAACTGTTTGACTAGAGTACTGGAGAGGTAAGCGGAATTCCTAGTGTAGCGGTGAAATGCGTAGATATTAGGAGGAACATCGGTGGCGAAGGCGGCTTACTGGACAGCAACTGACGTTGAGGCTCGAAGGCGTGGGGAGCAAACAGGATTAGATACCCTGGTAGTCCACGCGGTAAACGATGAATACTAGGTGTTGGGTGCCATAGGCATTCAGTGCCGTCGCTAACGCAGTAAGTATTCCACCTGGGGAGTACGTTCGCAAGAATGAAACTCAAAGGAATTGACGGGGACCCGCACAAGCGGTGGAGCATGTGGTTTAATTCGAAGCAACGCGAAGAACCTTACCAGATCTTGAGATCCAGATGAATAAGTGGTAATGCATTTAGTCCTTCGGGACATCTGAGACAGGTGGTGCATGGTTGTCGTCAGCTCGTGTCGTGAGATGTTGGGTTAAGTCCCGCAACGAGCGCAACCCTTGTCCATAGTAGCCAGCAGTAAGATGGGCACTCTATGGAGACTGCCAGGGATAACCTGGAGGAAGGTGGGGATGACGTCAAATCATCATGCCCCTTATGATCTGGGCCACACACGTGCTACAATGTCGTAACAAAGGGAAGCGAAGGAGCGATCCGGAGCAAATCTCAAAAATAACGACCCAGTTCGGACTGTAGGCTGCAACCCGCCTGCACGAAGCTGGAATCGCTAGTAATCGCAGATCAGCATGCTGCGGTGAATACGTTCCCGGGTCTTGTACACACCGCCCGTCACACCATGGGAGTCGGAAATGCCCGAAGCCGGTGACTTAACCGTAAGGAGAGAGCCGTCGAAGGCAGGTCGGATAACTGGGGTGAAGTCGTAACAAGGTAGCCGTAGGAGAACCTGCGGCTGGATCACCTCCTTTCTAAGGAAAAGAGAAGGAATGAAGTAGGGAGTTGTATTACTGTTTAGATGCCGAGGGCATCAAGAAATTTCCGGTGGCGATGCGCCCATGGGAAACACCCGTTCCCATCCCGAACACGACGGTTAAGACGTGGGCGGCCGAAAGTACTATACTGGCAACGGTATGGGAGGATAGGTGGCTGCCGGATCAATAAAAAAGCTTTAACAATGATCAGAGATCAGAAAGCTTTTGGTCTCTGATGACTGCTAAAGCGGTCAGAAGTTTGTACCTTGAAAACCGAATACTGAGAAATATTTTAATCCAGATATAATCTACGATTAAAAGACATCGAAAATCCAAAACAAGAAAAAATAAATCATTCTTATGAGTAACGCTATACATCATAAGAAATGAGAACTAAGATTATCGAAAGATAATGGACAGTTCCTATAAGCTGACTGAAAATGGTTAAGCTGTATAGGGCGCAGGGCGGATGCCTTGGCACCAAGAGCCGATGAAAGACGTGATAAGCTGCGAAAAGCTGCGGTTAGATGCAAATAATCCTTGATCCGCAGATATCTGAATGGGGCAACCCGGCAGAGAAGACCTCTGTCATCCTTAACTGAATCCATAGGTTAAGGAAGGGAACCCGGTGAACTGAAACATCTAAGTAGCCGGAGGAAGAGAAAACAAAAGTGATTCCGTAAGTAGCGGCGAGCGAACGCGGAAGAGCCCAAACCAGGGAGCTTGCTTCCTGGGGTTAGGACTGTATAATCGATGGAGACTGCTAGAAGAATGGCATGGAAAGGCCAGCCAGAGAGAGTGAAAGCCTCGTATCCGAAAGCGGTCGAAGCGAGACAGTATCCAGAGTAGGACGAGACACGTGAAACCTTGTCTGAACACGCGGGGACCACCCCGTAAGGCTAAATACTACTTGGTGACCGATAGTGAAACAGTACCGTGAGGGAAAGGTGAAAAGAACCCCGGGAGGGGAGTGAAAGAGAACCTGAAACCCTGTGCCTGCAAGCTGCGAAAGCCCCATACGAGGGTGATCGCGTACTTTTTGTAGAACGGTCCGGCGAGTTATGTGGAGAGGCGAGGTTAAGTACTTAAGGTAAATAGCCGAAGGGAGACCGAGTCTGAATAGGGCGACAAGTCACTTCACATAGACCCGAAACCGGGTGATCTATCCATGGACAGGATGAAGCGGCCGTAAAAGGCTGTGGAGGTCCGAACACACATCCGTTGAAAAGGGTGGTGATGAGCTGTGGATAGGGGAGAAATTCCAATCGAACTCGGAGATAGCTGGTTCTCCCCGAAATAGCTTTAGGGCTAGCCCTGTAGCATGCCTAATGGAGGTAGAGCACTGAATATCCGCGGGGGCTTCACCGCTTACCAAAGATTATCAAACTCCGAATGCCATATAGGCTGAGCGCAGGAGTCAGACTACACGAGATAAGTTGGGTAGTCAAAAGGGAAAGAGCCCAGATCTACGGCTAAGGTCCCAAAGTGCGTGTTAAGTGGAAAAGGATGTGGGATTTCATAGACAGCTAGGATGTTGGCTCAGAAGCAGCCACACATTCAAAGAGTGCGTAATAGCTCACTAGCCGAGAGGTCCTGCGCCGAAAATTACCGGGGCTGAAACACGACACCGAAGCCTAGGGATTGGATGTATCTACGGGTACATCTGATCGGTAGGGGAGCATTCTGTACTGCATAGAAACTGTACCGAAAGGAGCAGCGGAGTGTATAGAAGAGAGAATGCCGGAATGAGTAGCGAGATGGAGGTGAGAATCCTCCAGGCCGAATATCCAAGGATTCCAGGGTAAAGCTGATCTGCCCTGGGGAAGTCGGGACCTAAGCTGAGGCCGAAGAGGCGTAGGCGATGGACAGCAGGTTGATATTCCTGCACTTATGTATATCAGAACTGTGGGGACGCAGGCAAAAGGGTCGAGCCGGGGAAGGAAGAACCGGTCCCGCAAGGGGGAACGAAAATAAGTAGAGAAGCGACAGATATGACTGCCAAGAAAAGCCACTATAGCGTATACATAACCCGTACCGTAAACCGACACAGGTGGATGAGGAGAGAATCCTAAGGCCGACGGGAGAAGCATTGTTAAGGAACTCGGCAAAATGTCCCCGTAACTTCGGGATAAGGGGAGCCTGAGAAATCAGGCCGCAGAGAAGAGGCTCAAGCAACTGTTTAGCAAAAACACAGGTCTATGCGAAACCGAAAGGTGAGGTATATGGGCTGACGCCTGCCCGGTGCTGGAAGGTTAAGAGGAGAGGTTAGAGCAATCGAAGCTTTGAATTTAAGCCCCAGTAAACGGCGGCCGTAACTATAACGGTCCTAAGGTAGCGAAATTCCTTGTCGGGTAAGTTCCGACCCGCACGAAAGGCGTAATGATTTGAGCACTGTCTCGGCAATGCACCCGGTGAAATTGAAGTACCAGTGAAGATGCTGGTTACCCGCGCCAGGACGGAAAGACCCCATGGAGCTTTACTCCAGGTTGATACTGGGGTCCGGTACCATATGTACAGGATAGGTGGGAGACTAAGAAGTAGTGACGTCAGTTGCTGCGGAGTCGCTGTTGGGATACCACCCTTATGATGCTGGGCTTCTAACCAAGGATCTTGAAACAGGTCCGGGGACAATGTCTGCCGGGGAGTTTGACTGGGGCGGTCGCCTCCGAAAGGGTATCGGAGGCGCTCAAAGGTTCCTTCAGAATGGACGGAAACCATTCGAAGAGTGTAAAGGCATAAGGGAGCCTGACTGTGACACCGACGGGTGGAACAGATACGAAAGTAGGACTTAGTGATCCGGTGGTATGAAAGTGGGATTGCCATCGCTCAACGGATAAAAGCTACCCTGGGGATAACAGGCTTATCACTCCCAAGAGTTCACATCGACGGAGTGGTTTGGCACCTCGATGTCGGCTCATCGCATCCTGGGGCTGTAGCAGGTCCCAAGGGTTGGGCTGTTCGCCCATTAAAGCGGTACGCGAGCTGGGTTCAGAACGTCGTGAGACAGTTCGGTCCCTATCCGGCGCGGGCGTAGGATATCTGAGAGGAGCTGTCCTTAGTACGAGAGGACCGGGATGGACGGACCGCTGGTGTATCAGCTGCATCGCCAGATGCATAAGGCTGGGTAGCCACGTCCGGAAGGGATAAACGCTGAAGGCATCTAAGCGTGAAGCCCCCCTCAAGATGAGATATCCCTGCTTCGGCAGTAAGACCCCTTAGAGAGTATGAGGTTAGATAGGCACAAGGTGTAAGCATGGTAACGTGTTCAGCTGATGTGTACTAATAGGTCGAGGGCTTATCCAAAGAAGGTTAGGAACAAGAAAGAGGTTAGGATTTAGATTATCAGTGTTCGGTTTTGAAGATACAAGCATAAATTAAAAAGTTTAAAATAATAAGTGTCGTAGCAAAGATGTATGATTTCTCTGTTACGACACTTTTTTATTATTGTAAAATACTCTACTATTGATACTTGATTGCTGTAAATACTTATATCATTTTTGGGGATTATTGTAAAAATCTCATGCCATTATTTTTTGATTTTGGAAGAATTTTTTCAACTTTCTCTATATCTTCAGCTTCTGTTTCCTTGAATTTATCGACAATATCCTTTCTACAGTCAGGACACAATTTTCCTGACGAGACGGGTTTGCCGCATCTGTCGCAAACAGCCCCTAGATTAACAGCATTGGATGAGATAAGTCTTTCTTCGCGGACCCATTTTATCAATGTGTTAATTGGTACGCCCGTTGCCAGAAAAACTTCTTTTCCTTCAGCACCAGGATATTGATCAAGGAATTTTTTAACAAGTTGAAATTGAGCTTCATCTGTACGACGACATTCCGGGCAAAGGATATATCCGTAGCCCGGGTACTGAAATACTCTATGGCAAGTCGCGCAGTTTTTTAATTCCATATTATCTATTACTCTTTGCTATTAAGAACTATCTTTTAAGTTCCGATTAACAGAATCCAAAATATTACATTCTCTCATTTAAAAGATAATCCCATAAAAACATGGTGTCAATTAATAATCGGTATAATTATTCATAAAACAAAATTAAATAGTGTCCGATTATATAAGACGATTATATTATATTTAATATATTGTTAGACGAAAAAGAAAAATACTTAAAATTTTCTAAAATAGATAAGTAAAGAGCACTACATGAAGAGAAGAGAAAATAAGAAAGATGTATATTTATCCTGTGCGTATTATATGCGCTAAATATATTGAGAATGTAGCTGATTACAAGGAGAAAAGGTATGAAAATGGGGAAAATTACAGTAGATCCAAACTGCAGGATAAAGTTTAACAATAATGTGGACTACTGTGTTGGTACAGGTCGATTAGGGCTTGCGCTCACTGAAGAATATTTAAAAGAGCTGGAATTTGTTCAGAAGATGATAGGCTTCTCATATATAAGAGGCCATGGTCTTTTTTCTGATGATGTCTCTATTTATCATGAATACGAAGAAAATGGAGAAACAAAAGTAGAATATAACTATACTTATATTGATAGAATTATTGATAGCTATCTAAAGCTTGGTATAAGGCCGTATTTGGAACTTGGTTTTATGCCCGGGCAGCTTGCAAGCGGAACTCAGACTATTTTTTATTGGAAGGGAAATACCACACCGCCCAAGGACTACAAGAAGTGGACAGACATGGTGATTGCTCTTCTGGTGCATCTCAAAAAGCGCTATGGAGAAGAGGTTACAAGCTGGCCTATCGAAGTCTGGAATGAACCAAATCTTCCTGGATTCTGGTACAAAGCGGATATGGAAGAATATTTTAAGCTGTTCAAAGAAACATTTCTGGCAATTAAAGAATATGACTCACGGTTTAAGGTAGGTGGACCAGCAATTTGCGGAGTTAATGATGCCGTGTGGATTAAAGCTTTTCTTTCTTTTTGTAAAAGGGAAGGACTTCGTCCTGATCGGATAACAAGGCATCATTACACAGTTGAATTCCCTGAGCGAATTGGACATTATGACTATTCCAAGTTGGAAGACTCTGAGATGCGTTTTGCGAACCTAAAGTCTACAAGGGATATTGTGGATTCTTACGATGAATTTAAGGGACTTCCAATCCACCTTACAGAATTCAGCACATCATACACACCCAAAGGGGTAATCCACGATACCAATATCAATGCAGCTTATCTTGCACGACAATTATCGAGACTCGGTGATGACAACGAAGCATATTCTTACTGGACTTTCGGTGATGTGTTTGAGGAACAGGGGGTACCGGATTCTCTTTTCCATGGAGGATTTGGAATGGTAGCAGCAGGTAATATACCAAAGCCTACCTTTTGGACTTTCTATTTTTATAAACAGCTCAAGTTATTCAGCGATGAATGTGTTTATAGAGATGATAACGCAGTTATAGTCAAAAAAGACAATGGCTACTCTGGAATCCTGTGGAATATTGATGAGGAAGATGAAATCAGGGAACTTTTGATGGAAGTGACAGATAGTTCAGATTATACGCTTATTACAAAAACAGTTGATGAAAACTGTTGCAATCCATTGAAACTCTGGCATGATATCGGCGAACCGGCTTATCCAACGCATGCAGAGACTGAGCTAATTAAGAGCGCTGCGTGGCCATTGACAGAAAGTACAGTTATATCAGCAAAAGACGGAGTTGTGAGTAGTCAGATTACTGTAAACAGAAATGGAGTAGTATATTTTACTCTCACAAAGAGGCAGCTTACATCGGATCGCGGATATGATTATGACAAGGTAGTTTCCTACCACTAATATACTTAGCGACAAGGAATTTGTTTAACATGTTTTAGTATTTTAATTATTGTGTCCAGATAATTACTGCCTGAAATCATTTCAAGTTCGTCATCGGTCAGCTTAATACCGGAACTACTTAGTTTTTTTAATGCTTCATCAGCACTTTTTGAATTTTCGATATCCTTAATTAAATTGTTCATATCCATGATTATTCCTCCGTTAATATAAGGATGGTTTATTAAATACTACAATAATTATTACGATAATACGAGAATTAGAGCATTAGATTATTGTGAAAAAAATATGAAATAGTAATTAAAGAACGAGGCTTTCTTGCTTTTTCTGATAGAATAGTAGGAATGAAAGTTAGGGAATGGTTATAGATCAATGAATATTTTAAACGTAGAAAATGTATCAAAAACATATATGTCCAAGCCTGTTCTCAGTGATGTATCGGTGGGAATAAGCGATACGGACAAGATAGGTGTGGTTGGAACCAATGGTACAGGCAAATCAACTCTTTTATCGATAGTTGCAGGGGTTACAGAGCCTGATAGTGGGCAGATAGTTGCAAATAATGGGCTTAGAATTTCATATCTTCCGCAGAACCCTGTGTTTGACATGGACAAGAGCCTTTTGGAAAATATAGCAGACACAATTTATGCAGGAGGCGATCATTGGGACAAGATGGGCGAGATCAAGGCTAATCTCGCCAAGTTTGGAATAGATGATCCGGAGTGCAATCCATCTATTTTATCCGGTGGACAGAAAAAGAGAGCTGCGCTTGTAGCGGCAATCATGACACCATCAGATCTTTTGATCCTGGATGAGCCTACTAACCATCTGGATTCCGGTATGATAGAGTGGCTTGAGGATTTCTTGCAGCATTTCAGAGGAGCACTCCTGATGATCACTCATGACAGATACTTTTTGGACGAAGTAACCAATCAGATTCTGGAGATCGATAAAGGCAGTGTTTATCGCTATGAATCAAATTATTCAGGCTTCTTGGAGCTTAAGCAGCAGAGACTTGATTATGAGCAGGCTGCGGAGAGAAAAGCCCAATCGCTTTATCGCAAGGATCTGGCCTGGATGCTCAGAGGTGCAAGAGCCCGTTCTACCAAGCAGAAAGCTCATATTCAAAGATTTGAGGAGCTTCGTGACAGGCAAAAGCCAGAAGAGGAGAGATTTGTAGAGCTCAGTTCGCTTCCCAGCAGAATGGGGAATAAGACAATTATCCTTGAGAATATATCTAAATCCTATGAAGGGAAGAAACTTTTTAAAGACTTTTCCTATACCTTCAATAAGCTTGACAGAATAGGAATAATCGGGCCTAACGGCTGTGGCAAATCTACATTTTTAAAATGTATTATTGGCATGGTAGAACCTGATACAGGCACGGTAGAGATTGGCCAGACCATCAAGATAGGCTATTTTGGACAGGAAAATGAAGCCCTTGATGAGAGCAAAAGAGTTATAGACTATATCAAGGATACTGCGGAGTTTATCAGGACTGCAGAAGGACTTGTTTCTGCATCTGTAATGTGTGAGAGATTTCTTTTTACACCGGATATGCAGTATGCGCCTATAGCTAAGCTCTCCGGAGGGGAAAAGAGAAGACTGTATCTGCTAAGGGTTCTGATGGAACAACCTAATGTTATTATTCTTGATGAGCCTACTAACGATCTTGATATTCAGACACTCAGGATCCTGGAGGATTATCTTGACGGATTTGCAGGCATTATCATTACTGTCAGTCACGATAGATATTTTCTTGACCGAGTGGTTACAAGAATTTTTGCTTTTGAACCTGATGGAAGCCTGTATCAGAGCGAAGGCGGCTATTCAGATTATGTGGTTCACAAAAATGGGCTGGAAGATGCAGATGCTGCCACGGATTCCGGTAATAGGAAAAAGTCAGGAAATGCAAGTGGGAACAATAGTGCCGGCAGTAATAACGGTGACGATCAAGACGTGAAGTCCAATGGAAAATATCGAGCTCCGCGTGAAAAGACCAAGCTTTCCTATAAGGAGCAAAGAGAGTACGACACTATCGAAGAAGAGATTGAAAAACTTGAGCAAAAGAGTGAAGAACTTGAAGCTCAGATAGCTGAAGCTGCCACAGATTATCCAAGGCTGGTAGCTCTCAGTAAGGAAAAAGAAGAAGTAGATGCCGAAATTGAGCGTAAAATGGATAGATATGTTGAGCTGCAGGATATGGTTGATAGTTTTTCTAAATAAATAACTATTGCCAATTCGAACAGCTGTTCTTATAATGTTAGGTAGTGAGGTACAATATGGAATTATTAGAACAGCTCAACCATGCTCAAAAAGAGGCTGTAATTAGTACAGAAGGATATATTCGGGTAATAGCAGGTGCTGGAAGTGGCAAGACCAGAGCGCTTTCCACGCGCTTTGCATATCTTGTTAATGGCCTTGGCATTATGCCGGGGCATATTCTGTGCGTTACATTTACCAATAAATCTGCCAACGAGATGAGACAGCGAATACATGCACTTACCGGAGACAATGATACTGGGTATATCAATACCTTTCATGGATTTTGTGTATCGGTTCTTCAGGAAGATTCTCATGCAGTGCAGTATCCCAAGAATTTTCTGGTTCTTGATAATTCCGATATTGATGATATGCTCAAGATCATCTATGAAGAGAGAGGGCTGTCTCTTAGAGATATGACCTTTAGTTCAGCTCGAGATATGTTTGAGATCAGGAAGCTCTTCGAGGAACCTGAGTACTATTTAGATATGCTTACAATGCCGCTTGAAACGCTCAAGGATAAATATGATCAAGCGACAGAAGTTAAGGATATCTTGTTTTATGGCTATCTCTATCAAGAGAAGAAGTGCTTTGGACTTGATTATAACGACCTTATCAAGTTTACTCTTTATATATTCAGGGAGAATCCGGACATCAAGCTTAAATGGCAGAAAAGGCTTGAATACATTATGATCGACGAATTTCAGGATATTGACAGTCTGCAGTACGAGTTGATGGAGGTTTTGGCAGGTTATCACAAGAACCTGTTTATAGTAGGTGATCCGGATCAGACTATCTATACATGGCGCGGAGCCAATGTTAAGTATCTCTTGGACTTTGATCAGAACTTTCCTAGTGTTAAGACTATCATGATGAATGATAATTACAGGTCAACTCCACAGATACTTTATGCTGTCAATTCTCTTATAGACAAGAATCGCTATAGGATTAAAAAGGATCTGTTGCCTACTATTGCAGAAGGGGAGAGTGTCCTGTGCCATCTTGCCCCTAATACCACAGAAGAGGCTGACTGGATAACCGGTGAAATTCTTGTTCTGAAGGGTCTTGGCGTTCAGTACAAGGATATTACAATTTTATATAGAGCACATTATGTTACCAGAACTATAGAGGAAGGACTCATGAAAGAGAAAATTCCTTACACGATATATTCTGGAGTTCAGTTTTTTGGAAGGACAGAAATCAAGGATGCCCTGTGTTACCTTAGAATGCTGGTTTACAGGGATGATATTTCTTTTCGCCGTATTGCCAATGTCCCCAAGAGGAATCTTGGTAAAAGAAGGATGAGCTTTCTGGAACAATACGCTGCAGATAACAAGTGCTCTCTGTATGCTGCTTTGCATGAAAATCTGGATAATGAGCTGTTTAAAGGCACTAAGGCTGGGAAGTTCATTGACCTCATCGAGCATTTTGCAGCGAGCTATGAAGGACTTCCTGTGTCTGAAGTTCTGGCCAAAATATTAAATAACAGTGGTTATGAAGAAATGCTCAGAACAGAGGGAGCTCAGGACAGACTTGATAATCTTGCGGAGCTCAAACAGTCTGTATTTGAATATGAAACTACCTGTGGAGAAGAAGTTGGTCTTGAAGATTACCTCAAGCATATTGCGCTTTTTACCAACGCGGATTCAGATGCCGGAGATCAGGACAAAGTAAGACTTATGACTGTGCATGCGGCTAAGGGACTTGAGTTTCCTTATGTCTTCTTGTGCGGTATGAATGAGGGTATATTCCCTTCCAGAAAAGTTCGCACTTTGGAGGGAATGGAAGAAGAGAGAAGGCTGGCATTTGTTGCTATGACAAGAGCCCAGAAGAGACTCTTTATCACTGAGGCTGGTGGGAATACATTTGAGGGAATTCCCAGGTATCCCTCCAGATTTATCATGGATATAGATCCGGAATTGCTGGAATTTACCGAGAAACCTGATGACAATATGATCAAAGCTGTCAGGAAATTTATAGATAATGACAGTAGGCACCTTAAGGGCGCAGAGAAGCTGAACCTATTGGAAAAGGGGCAGCGTGTAAAACATGCTATTCTGGGAATTGGGACAGTTCTTGATATAAATTTGGATGAGGAGAGTTATCTGATCAAATTCGATGAAATGGATACTCCGAGACAGATTTCAATGAAGGTTAACCTGGCAAAAGAAGACTGAGATTATTAATATATATAAACGCAAACAAGCCACTTTCAGCAAGCTGAAAGTGGCTTTTAAAAAACAATAATAATTATTTAGATGCATTTTCTCCGGCGATTCTTCCAAAGACTACAATATCAGCAACAGCGTTTCCACCAAGTCTGTTAGCGCCGTGGATGCCGCCTGTAACTTCTCCGCAGGCATACAGGCCAGGGATTGGGGTTCCGTCAGTTGAAATGACCTGCGCATCTGTATTGATCTTAACGCCACCCATACAGTGGTGTATTCCGGGACCTACATTAACTGCGTAATATGGGCCGCTTGACAGGTCTGTAAGCGGAGTGCCTATATCCCTTGAAAAATCAGCATCTGTTCCGGAAGCTACGTATCCGGACCAGGTTTCAACAGTTTTGAGAAGGGCAGAAGTAGCATTTGAATCAAATTCCATAGCTGCAGCGAGATCTTCGAGAGTATCGCCCTTTACAAGATATCCGCTTTTATCCAGCTTCTTGATAACAGCAGAGCCCTCATACATTTCCTCATTGGCAATCAGCCAAACATTTCCACCGGTCTGAGCAACCTCTGCAGCAGAAACTGCATCTCTAGTACCGGTTTCATTTGTGAAACGAACACCTTCTCTGTTGACAAGGATGGCACCATCGCCTCGAAGGGCTTCACCTACAAGCGCGCCATCGGTCGGGATAACAGTAGGATGAAGCTGTATCTGTTCAAGATCAACGAAGTCTGCGCCTACTTCCCCAAGGAAATCTATTGCGTCACCACTTGCAGTGGCAACGTTGGTTGAGATATAGCCTGCAAGATCCGGACGGAGAGCGACTATTCTGTCCATGTTTCCGCCAAAACCACCGGTTGCAACGATGACAGCATTGGCATGGACGGTAATGTTTTCACCGTATTCGCCAATTCCACTAACACCACTGGCTTTACCGTCTTCCATTATAATCTTATTAACAGTAGCACCTGTTATTATTTCAACGCCCAATTCATCGAGCCTAACGCCCAGCGCAGATACAAGGAAGTTACCTACTGAAGTAACATTTCCTTCGGCATCTGTTGGTCTGTGAGTTCTCTTGGCACTAAGACCGCCCATGGTTCCAAGAGGACCGGATAGAGGAGCATTCTCTTTATCAAGCCAGTCTATTGCTTCTGACGTGTTCTCTGCCAGAGTTCTGACAAGTTCCGGATCGTTGATCTCTTTACCGCTCTTCATTGTATCTTCAACGAAAAGATCAACTGAATCTTCTACACCTTGTTCTTTTTCGTAGTGAGTCTCGGCAGCATTCATACCGGAGCTTGCTCTGCTGGTATTTCCGCCAAGGATATCGCTTTTTTCAAGAAGAATGACCTTTTTGCCATTTTCAGCAACAGTGATGGCCGCTGTCATTCCAGCGCCTCCGCCTCCAACAACTACTACATCAGCAGTTGCCTCATAATCCTCAGAAGCAGCGTTTCCCTTATGACTACCATCAGCAACAATCCCAGCTTCAGCGAGAGCTGTATTTACAGCAGAAAGGAATCCTCTTGAACTGTAGGTTGCGCCTGAAATTGCGTCAATCTGGGTGTTCTGAGTTTTGAGTATTTTGGTGCGAAGAGCTTTGATAGCACTGCCGCCGATAGATGGAGTTTCGCCTTCGGTCTGATATGTAATGTCTGTGATAGTACCATCTTCAACAAATACTGATACCTTGATTTCTCCTGCGAAGCCATCGGCTGCTCCATCATATTGATGACCTTCATGTTCAACAACATAGGTGCTGCCCCAGATACAGAAAGCAACCAGTCCTACACAGGCTATACAGGATATAATTCTTTTAGATAGTGTGCTCATGAATCTTTTCCTTTCACAAACAAACGAAATAACATCTACATATAATTACTATAATACAAATCAATAATTTTGTGACATCTTTTATCTAAAAATAATGTTTTGTTAACAATCTTTTTCTATGTATAGTCGCAAAATAGTCTTTTAAATTCTCGAAAAAACGACTATCATTAATATAATGAGGAGGATTATAGCGGTATATGTATTATGCAGCGGTTGCCTTTTTAGCTTTTACAGTAAATATAATATTGAACTGGAATTCTTTTAAGAACGCATGGAAAAAGACAGATGCGCGTGATACCAAGAAACTGTCGCTAATCCGTTACGGTCATTTTTTGCTTGCTGCTAATTGTTTCTTTCTAACGGAGATATGCTGGGGCATTATATATGATCATCATGACGTGCCGGAACTATTTCCTATTGTATATTCAATTACAGTTTTTTATTTCCTGTTCATGCTGCTGACTATGTTGACATGGGCACGTTATATAGTGGCCTACCTTAATAAAGGCAATTTTCGCAGTAAGATACTTACTATTGGAGCGTGGATTATGTTCCTGCTCGGTATCGGCTCTCTGATGCTCAACCGGTTTTATCATTTTATTTTTTCCTATAATGAGGCGCATGAATATATTCCGGAAAAAGGAAGTCTTGCTACGTTTATTTTTGTTCTTGCATTCTATGCCATACTCTCAATGCACATGTTAATAGCAGCGTACAAAACCAAGGGCAGTCAAAAAATAAGATATATGGCAGTGGCTTATACTAGCATGGCTCTGGGTATTTTTATGTTTCTGCAGATCCTTACCTCGTTCCTTCCACTGTATGTCATCGGCCTCCTGATTGCTATATGTATTGTCCATTCTTATGTAGAAGCCGGAGAAAAAAAGGAAAAAGAAATTCAGGACCATATTACGTCAATAATGGCGGAAGACTATGAAGCGATTTATTACTTTGATATAGAGACAGGAGAGTATATTGAGTTTTCCAGAAGCCAGAAATATTCTTTTTTGGATGTGACATATATAGGAAAAGACTTCTATAAGGAATCTCTTGATAATATTGAAAAAACTGTGCATCCTGATGACAAGGAGTATGCAAGAAGCCTATTTAATAAAGAAGCAATGATCAAGAATCTTGAAGGAAAAAGGTCTTTTTCATACAAATACAGGTTGATGGTTGATGGATATCCCAGATATTTCCTCTTTACATACAGAGGCGCCGGAGATGATAAACACATTATCCTTTATGAAAAAGATATAGATGATGAGCTCATGGCTGAGAAAAAAATCCATGAGAATCAGGAAAAGAGCATTACATTTAGCCGTATTGCTGAAAGTCTTGCTACCAACTATGATGCTATCTACTATGTTGATGCAGTTGATTCCTCGTATGTCAGTTTCGAAGCTAATGATATCTTTGGACAGCTTCAGGTTAGCCAGCTTGGCAAAGAGTTCTTTGAGGAATGTTATAGTAATATTCCAAAGATCATTCATGAACAGGATCGCAACCGAGTTGTTGAGTTTCTGGATAGAGACAAAATGATCACAGCTCTCGATAATCACAGGAGTAGTTCTATTGAGTACCGACTACTGGTAGATGGTTCCTCCCAATATCTTAGGATGATAGCCCGTAGGAGTAGTGATAGATCACACTTTATTATTTGCGTAGAGAATATTGATGATGAGGTCAGACGAGAAAAGCAGCGCCTCAAAGAGCTGAAGACTGAAAAAGAGCTTGCTAGGCGAGATGAGCTAACGGGAATTAAGAATAAATACGCATATAAAGAGCTGGAAGAGTCAATACAGGGAAATATGGACCACGGCCTCGATTACTTGCCATATGCTCTTATTGTATGTGATGCTAACGATCTCAAAAAGATCAATGATACTTTGGGCCATGTTGCCGGGGATGAATACCTCAAAGCGGCTGCCAAGCTCTTGTGCTATACCTTTGTGCATAGCCCTGTTTTCAGGATTGGCGGGGACGAATTTGCAGTTTTTCTCAGGGGCGACGATTATTATATTAGAGAAGAACTCATGGAAAAACTACGTAATCAGGTGCTTGAGAATCAAAAAGCCGGAAACGGAGTTGTGCTTGCTTCGGGAATGTCGGAATATAATCCAAAGACAGACACAGTGGTATCAGATGTGTTTGAACGAGCGGATAAGGCGATGTATGAGAATAAGAGAAAACTGAAAGGACAATAAATGATATTGGAACCACTGCTTACGGAGACAAATCGTATAGCAGTGGTTTTTACATTTTACTATATATTGTCCACAAAAGTGGCTATAATCATGTCTATAAGGTGTTTATCACATTTTGGCGGGAGTATATGGTATGGATATAAGATTTTTGGAAAAAGAAAAAGTATTTGTAATTGACACTGAGAACACTAGCTATGTCATGGGGATTTCCGGTGAAGAAGGGCTTTTAGGACATCTATATTATGGGGATAAAATAGATAGCTCAGATGTAGCATATCTGTGGAAAACTGTCGAACCTCAGGTGAATCCGACAGTGGATATGAGGGACAGGAGCTCTTTCCTTGACAGATTTCCTTTTGAGTATTCCTCTAACAACGTTGGAGATTACAGGAAGAGCAGCATAGAGATAACTGATAGTAACGGACATACAAGTCTTTTGCTATGCTATGAATCCCATGAGATATTTGGCGGTAAAAGAGCTATAGCAGGACTTCCGGCTACTTTTGGAACTGCAGATGATTCCATGAGCCTTGAAATAGTACTTGCAGATAAGGTTGTTGGGATCAGGTGTATTTTGTCATACAGCATTTTTGCCGGACTTGATGTGATCGCAAGATCGGTAAGGCTCGAGAACTTGTCAGATAACACAGTCTATATTGATAAAGTAATGTCTTTTACCATGGATATGGATCAGGAGGATTATAAATTACTGACGCTTCATGGATCATGGGCAAGAGAGCGCTGGATGGATTTTAGGGAAATCGGATTTGGAGATACTTCCATTGAATCCTTCAGAGGAGAGTCCTCGCACCAGTTCCAGCCATTCATGGCATTGGTACAAAAAGAGGATTCGCAGGATACAGGTAAGGTTTATGGTTTTTCTTTTGTCTATTCCGGTAATTTTGAGGCTGGAGTAACAAAGAGCCAGTTTAACAGTTTAAGAGTATACATGGGAATCGGAGCCAAAAACTTTAGATGGACATTAAGGCCGGGTGAAAAATTTGATGCCCCTGAAGTTGTAATGACTTATTCAGCTGGTGGCCTTGGAAAGATGACCAGGACTTTCCATGATCTTTTCAGAAATCACTTGATTAGAAGCAAGTACAAGGATATGGAGCGCCCTATCCTGATCAATAACTGGGAAGCTACTTATTTTGATTTTGACAGTGACAAACTCATCGCTATTGCCAGAGAAGCCAAGAAAAGCGGAATTGAAATGCTGGTAATGGATGATGGCTGGTTTGGAGAGCGAAATGATGATAATTCCAGCCTTGGAGACTGGTATGTCAACGAGGATAAGCTTAAGGGCGGACTTAAAAAATTAGTAGATGAAGTAAATTCTCTAGGGATGAAATTCGGCATATGGATGGAGCCTGAGATGGTTTCTCCCAGATCAAAGCTCTTTGAAGCGCACCCGGATTGGGCTATACAGATTCCTAGAAGAACACCTTGCAGGAGCAGAAATCAGTTGGTGCTTGACATCACCAGGCAGGAAGTGCGCGATTATATATATGGAAGGATCAGAGCTATCCTTACAAGTGCCAACATTGAATATGTTAAGTGGGATATGAACAGGCAGTTGTGTGACCTGGGTTCTCTGGGACTGGACAAAGAGTCACAGGGAGAGCTAAGCCATAGATATATGCTGGCAGTATATGAGCTTCAGGAGCGCATGATAACTGAGTTTCCGGACCTTCTTCTTGAGAACTGTTCCGGAGGAGGAGCAAGATTTGATGCAGGAATGTTGTACTACAGTCCTCAGATTTGGTGCTCGGATGATACAGATGCAATTGAAAGGCTTGTAATACAGGAAGGAACAAGCCTCATTTTCCCTCTTAGTACTATGGGAGCACATGTATCTGACTGCCCTAACCACACAGTTGGAAGGACTACGCCTTTTAAGACACGCGGAGATGTTGCTCTAGCGGGAACATTCGGGTATGAGCTTGATATTACCAGGATTCCTGAAGAGGATAGGGCTGATATTCCTCGACAGGTTGCTGTATATCATAAGTACAATCATCTTGTAAGGGGCGGAGATTACTATAGAATTGCCTCCTATCAGAGAAATCATGAATATGACGCATATATAGTAGTTAGTAAGGATAAAAAAGAAGCACTGATAACCTATGTTCAGGTGGTTGCAAAGCCTAATTCTTCGAGGAAGTTACTCAAAGTTCCTGGACTTTTAGCAGATGTACGTTATCAGCTTGAAGGAAGCGATGAAGAGATTCTTGGAGCTACCCTTGAAAAAGTGGGACTGTCTGTGAATCCGCTAAATGGAGATTACAGGTCAGAACTGATACATTTGATAGCCAGGAAATAAATATAAACTGCCTTTCTTTTTGCTTCCTTTTTGCATGGGGGAAATGGCCGGGATTACCCGAAAACTGGATTATCAGAATCTGCTTGGAATGAATGTGTTGATAATGCGAATCTGATATATAACATATTTATAATATATAATAAATCACATGATAAAACATGTTACTTGCGAGGGCATTTACATAATGGTAGAATGATGAAAATCATGCAGACATAGCCATGTTTGTAAATCTATAAGATCAGAATAGGAATAAGAGGCACATTAATGAATAACAGACTTAGACAGATAGGCTTTTTGATACAGGGCTGGCTCTCACGCGCTTTGTATGGCAGAAATGGTTTTGATAACCTGGCAAGAACATGTAATGCAATTGCACTTATACTTCTTGTGATAAATATATTTGCTCAGAGCGTAGTGGTATATTTTATCTGGGTTGTTCTTTTTGGATATTCTCTTTTCAGGGTATACTCCAAGAACATTACCAAAAGATATGCAGAAAATCAGAAATTCTTACAGATAACTGAGAGCCCCAGAAGATATGCGAATCTCATGAGACTGCAGTGGAGAGACAGAGAAGTCAGTAGATATTATATCTGTAAAAAATGTCATCAGCAGATCAGAGTGCCTAAGGGAAAAGGCAGGATCGAGATCAGATGTCCTAAATGTGGGGAACGTTTTATAAAGAGGACATGAGGCCTGTTAGAAGAGAGAAAAACTGAATAAAACAAGGGGTTTATAGAACAGTAAAAAATGTTTTGGATTATAGCAACACTTTGCGCCTTTTATGTAAAAGGGTTATGCGGATTTGCAAACACACTTGTGTTTACATCAATACTGAGTTTTGGAACAGCCAATATAAATATTTCTCCGGTGGAGCTTCTGCTGGGATATCCAACAAACCTGATAATAAGCTGGAAAGAGAGGAGACATATTGATCTTAAGATATGTATTCCTCTTTCTCTTATGGTAATAGTTGGAAGCCTGGGAGGAGTTTTTTTTCTGAAAAATGCTGACGTTTCTGTTATAAAGATCATCTTCGGAGTTCTGGTGGCCCTTGTTGGTGCTGAAATGCTGGTAAGAGAGTTGCCTCAGAGGCAGGCGAAGAGCTCTAAACTTCTGCTCACAATAATAGGAATTGTTTCGGGAGTACTGTGCGGACTCTACGGCGTAGGTGCCCTGCTTGGGGCGTATATAGGCAGGACTACCACCAATGCCGATGAATTTAAGGCTAATATCTGCACGGTATTCATGATCGAGAATACATTCAGGATAATTCTGTATGGATTTTATGGGATCATTACTTTATCTGCACTGAGGCAGGCACTTACACTTGCGCCTTTTATGCTGATAGGACTGATCGCAGGAATGCTTAGTGCCAAAATAATTGATGAAAAAATGGTCAAAAGAATAGTGATCATTATGCTCATAGTATCAGGAATAGCACTGATTCTGACTGTTTAAGATAAAAAGCACTCTAGGAGATGTTTGATAAGTATGTTGCTCTTGGAAAAAAGACTAAGTTTCCTAATGTTAATATCTATGATGGATTTGCAGAGAACTATGATTCCTACAGTGCTGAGAGATCTGCTGTAACTATAATATCCATGCGTTAAGCGTGTAGATGAAGGGATATGCTACTTTGTCTGATAACTATAAAAAAATAACAATTAAAGAATACTTGAGGTTGCAAAGAGGCTGAACTATGTACCAAACCTTAACGGTAGAAATCTCAAGGCACAGGTCAGTATGAATGCCGGAGTACCTGTAATGTTCGGCGTCCTCACTACAGATACAATAGAGCAGGCTGTTGAGAGGGCAGGCACAAAAGCCGGCAACAAGGGCTTTGAATGTGCTCAGGGAGCAATTGAAATGGTTAATCTCATAAGGGAGATGAATCATTAAAGATTTTGTCTCATCCTGAATATGAGTGTAAAATGTAATGAGTAGAATAGCATGGGATGAATGAAACATAAATCCTATAGCAGATAAATTTTTAGATGTTGAACCTGATAAGCAATAGCTATGAAAGAAAAGAGGGACTTATGGTAAAAGAAATAGTTGGAGATCTTTTAAGACAGCCTGTAGATATTGTAGCCCATCAGACGAATTGCGCGGGTAAAATGGGAGCGGGAGTCGCACTTGCAATAAAAAAGCAGCTGCTTACTTCTGACGCTTATGAGAAATATAAGTCAATATGCAAGGAACAGGGCTCTGATCTTTTGGGTAAGACACAGCTCCTCGAGGCACCGGACGGGCGGATTATAGCCAACTGCTTTGGGGAAAATATTCCTACCGGAAAAGGCAGAGATACTGATTATGACGCTCTTATGCATAGCATTGCCAAGGTTCGAAACTACGCAAAAAGAAGCGATCCAATGCTCTCTGTCGGGGTGCCCGGCTTAATAGGATGCGGCCTTGCCGGAGGTGATTGGCGAATTGTAAGAGATATGTTATACAAGCTATTTGGCGGAGAAGGCGAGCCTGATCTATACATTTGCTATCTGGATGAAAAAGAGTATAGGAAATGGAATTATTAGGAGCAAACTTGATTTAATTACGTTCTCATCTATACTAAAGATTCGTTTATGGAGATAACCGATAAAAGGTGGTATAATTGACGACGCTGTCGTAAATTATTCAAAGAATTCATTTAGAGGAGTCTTTAGTAACAGAAATGAAAGAAGAAAAGAAATTGGGACTTATGTCCCTGATACTGATGATTTTTACATCAGTTTATGGTTTTAATAACATTCCAAGATCATACTATTTGATGGGCTATGCAGCTATTCCTTGGTTTGTTATAGCAGGTATTTTGTTTTTTATACCTTTTGCTTTTATGATTGCAGAATTTGGATCTGCTTTTAGAAATGAGACAGGTGGAATGTACTCTTGGATGTGCAAATCCGTAGGTCCCAAATATGCATTTATTGGAACACTTATGTGGTACACCTCATACGTACTTTGGATGGTAAACGTATCATCCGGTATCTGGGTGCCTGTATCAAACATCCTTTTTGGTGAGGATAATACAGCAAGCTGGTCACTTTTTGGCTCACAGTTTTTATCCGGTTCAAGATTGCTTGGACTTATGGCTGTTATTTTTTTCATCATTATTACCTATTTTGATTCAAAGGGCCTTGACAAGATCAGCACTGTAACATCTATCGGTGGTACAGCCGTTCTTACAATCAATATCTTAGTAGTTGTTGGTTCGATTGTTATGATCATTGCACGCCATGGACAGTTTGAGCAGCCATTCGCAGGTCTTGAGTCTCTTAAGACTCCGCTCAATGTATCTTACCAGGGTAGTCCGATCATGATTTTGTCCTTTATTGTATATGCTCTTTTTGCATATGGCGGAATCGAAGCAGTAGGTGGTTTTGTAGACAAGACTGAAAACCCCAAAAAGAACTTCCCTTTGGGAATTGTGTCAGCAGCACTTGTTATAGTTGTTGGATATGCTCTTTTGATCATGTTAGTTGGTTCTTTTACAAATTATAGTGATATTCTCGGATCGGAAGACATCACACTTGGTAATGTTTCATATGTGATCATGTCCAATTTTGCTGCATCATTCGGTAAAGCGTTTGGTGCATCACAGGCTGCGCAGGTTGCTCTTGCTCACGGCTTTGCCAGAGTATATGCACTTATCATGCTCCTTGCGCTTATGGGTGCTATGTTTACACTGGTTTATTCTCCATTAAAGCAGCTTATCGAGGGTACGCCCAAGGAGCTTTGGCCAGGAAAAATAGGCGAGATCTCAGAGGATGGCATGCCCAAGAATGCGATGTGGTTACAGTGTACAATTGTCTGCATTATGGTACTTTTAGTATCTTTTGGTGGCAACACAATGCAGCAGTTTTTTGTTATTTTGACGGCTATGGTAAATGTAGGAATGACAGTCCCTTACATGTTTATTTCTTTTGCTTTCCCTAAGTTCAAAAAAATGAAGGGCCTTGACAGAAGCTTTGTTATTTTCAAATCGCAAGCTTCAGCAAATATCTGGGGATATGTAGTAACACTTACTCTTTTCCTTGCAAATGCATTTGCTATCATCCAGCCGGCATTAGATGGCGATTTCAAGACTACATTTTGGTCACTTGGCGGTCCTGTAGTATTCGGATTAGCTGCTTGGATCATATATACAAACTATGAAAAGCGGCTTGCAGCTGATACGAAAAATGACTTGGAAAATAAACGTGCCAGCTAAAAAAATTATTTTCCATTATTGCCTTTCGTTCGTATAAAAGAATATAAAACGATAACGAGGGGGTTAATACCAATGGAAAATTTAAAAAACATACTAAGAAATGAAAGTAAAAACTCTGAATTGGGTGATACTACAACAAAGACCAATAGTGTAGCGCTTGAGAAAACGCTTGAATCTATCGGCGCTTTGTCTGCTGTATCAAACATAAGGAAAAGTTCCTTGTTTTTACTTAAGCAGTGTGCGTTTTCCAGTATGACTTGAGCGAAAAGCTTAATAATTTTGAGGATTTACCTTATATAGACTCTGATGATACATATCAATATGGCATCAGAGTCTTTTATTGCATATAATAAAAAGATGTATAAAACGAATATTTAGGAGAATTACAAGCTGTAATAAGAGGAGTACGTTTATGAAAAAAAGATCTATCAGACTGGCAGCTATATCTACAGCTGCTGTGATGTTACTGAGTGCCTGCACCAGCACAGGAAATGTAGTAAATGAAGATGGTGCATCGGGAGTTTCTATTGAGGCAATTGCAGATACCTCTAATGCAGAAAACAAGTCAGGCAGTGATACAGCTACAACATTCCCGGTAACTGTTGTTAATCACCCTATTTCTTCGTCTCAGGACGGTAAGGTTCTTTGCACTGGAAGCTATCCGGAAATAGTCCTGTCAGATGAGTATAAAGAAAAATATCCAAAGCTCTCTGAAAACATAAATAATTACAATGAAACCAATAGTTTCGGAGCAACTAGTAACATTTCCGAATATGCCGCATGGGCACTGGAAGATACATACTATACCGAAGGCTATTTTGATACAAAAACAGCCGATATTGTAAGATTTGATGATCATCTTTTTACTATATTTGAAATTAGTAGTAGTTTTACCGGAGGCGCTCATCCGAATCATTATTCATATGCCACAAATTATGATCCTGCAACCGGTGATATTGTAAGGCTTGATAAGGTTTTAGATGATTCATCACTGCTTTATGATGGCATCAGAACAGAACTTGAAAAGAATTACCCCGGAATTATGGAAGAGGTAGACAGTTTCTATTTTCCTGAAGAAGGTCAGGATCCTGATCAGTTTGTTCAGAAACTAAGGGACGATACTTATACCTGGACAATAGATGATAAGGGATTAAACATTTTCTTTTCACCCTATGAGATTGCTTCATATGCAACAGGAGATCTTCAAGTAGTTTTATCCTCAAAAGAGTATCCTGATCTTGTAAAAGCTGATTATATGCTGGATCAGCCTCAGGATCTTGATTCTATCGTAAACCACACAGATGCTGACACAACTGAAGTTGCTCCGAGTGAGGATGAACCAGATCCGGAAAGCGTGTCTGTTTCAAACCCTACCTGGAAATATTATAAAGCTGCGGATGCTATAGTTCCAGCTGGCAACCACTTAACGCTGACCAAGACCAATGAAGAAAAATCAGACTATCTCGATAGTTATGCCTGGGCTGAGGCAAATGATCTGCAGACAGAAATGCTGACCCACGAGGATGACAACTATTTTTATAATGGAACAAACGAAGTAGAATATGCCAACTCCTTCCAGGGCATAGATATTTATGATACTGAGATGGATACAATGTATTATAGCTTTGATTTGTCTGAACTCTGCGATGGCCCTGACTATGAACAGGAGAAAGTCTCTGCTGTTCACCAGTTCATTCGATATGCCACAATAGTTGACAATATTCTATATTTAGAAATCGGTCATCTTGGCTATGCCTCTGAGGAACCTGAATCCAGCTATATTGTAGCTATAAATCTTGAAACAAATGAACTAATATTTAGAAGTGAACCTCTTGTAGCAAATGGAAGCAACTTCAAAATCGTAGATGACACGATCATATGCGGGTATGGATTTACTTCCGAGCCGGATTATATCTATCTTCTTGATAGATTTACCGGAGAAAAATATGACGCGATCAAGATAAATTCTGCAGCTGACCAGTTCCAGGTTAAAGGTGACACTTTATATGTAGCAACCTATAATACAGCTTATGAATTTACAATTACACACTGATCTACAGGCAGGTATTATGAAACAGAACACTAAAATCTACACACTTACGCATACTTTGATGCTACTCGTAGCATCTTTTTTCTGGGGGACTACTTTTGTAGCTCAGAGCCTTGGCGCAGAATACGTAGGTGCAGGAACTTACCTTGCTCTCAGGACCTACATTGGAATTATTTTTCTTTTGCCATTTGTATTGTACAGAGATAAAAAAGAAGTTAATAACTTAGGCCTCGGGCTGCAGGAGCTACAGGATAAACGCAGCAGAGAGAAACAGGCCTTTATAAAGGGCGGCATGCTGGCAGGACTTTTCATCTTCCTTGCCAGCTTTGCTCAGCAGTACGGAATTGCCTATACTTCTGTTGCCAAAGCAGGTTTTCTTACAACACTTTACGTTGTATTTGTTCCGATAATATCACTATTCTTTGGACGCAGATTCGATAATAAACTCTGGATCAGCATTGCGCTCTCTGTTTTAGGCATGTATCTGTTGTGCATGAAGGGGAGCTTTTATCTGGAAATAGGAGATGCCCTGATGATTTTATCTGCCCTTGGATTCTCAATTCAGATTCTGGCAGTTTCCAGGTATTCCAAGAGAATTGATCCTGTTAAACTGACACTTGCTCAGTTTATTATAGAAGCGATACTGGCTACAATAGTAATGTTTGTAATAGAGAAACCAGACCTGTCATCTATCTATAGCGCTCTGCCCGCCATCCTCTACGCAGGAATATTCAGTAGCGGAATAGCATATACACTTCAGGCTCTTGGGCAAAAGAACTTAAATCCGGCCATCGCATCTATTGCCATGTGCCTGGAGAGTGTATTCGGAACTCTATCCGGATGGATAGTATTGGGCCAGCAACTTTCTCTTCGCGAAGCCGCCGGATGTATTCTGATGTTCGCAGCAATCGTACTTACACAGTTCCTTGGAAATTCATAAGTGCAGATAAAAAATACTAAGAGGATTTAGTTTCAACGTATATTAAAAAGATAAATTTATCATGTGCAACATATCATCAAGCTTAGCTTTTGCATCCTCTGCAAACGGTAATTTTTCTCCTATTTCAAGCGCAGCCTTGAGATGGAATATTGCTTCAGGAATGTCCTTGGTCTCGTAGGCGATGACTCCAAGATAATACTGATATACAGTTTTGGTATACATGGAAACCCGACTGCTTTTAATATATTTTGCAATCAGATTTTTGGCCTCTTCATACCGCTGATCCTTGATTGCATCCTCGATGTTCAGATCATCTAAGGTAAGTTCAACTAAAAAGTTACTCCTGCCGGAGTCTCTTAGCCCCTCGAGACATGTTTTGTAGACAGCCGCTTTTTCATCATCTCCTATATCATGGAAATAGCCCGCCAATCGGCATAAAAGAGCTTTATTCCTGCACTGATATGGGTTTGCCGGAACTAAGCCTTCATAGTAATTCCAGGCATTTTCATAATCTTTCATAGCAAGATAAGCTACACCGATATTCATTCTATTGCGCTTAGACAATCTTCTGAATATGCTTTTCTTGCAGCGTATCAACTCGGCCTTCACATATTTTTCTGGATCGCACAGTGTGTTCATTATACCGATAAAGAAAGCTTCATGAATATAAATTACCACTATCAGCACTATTACACATACAGCAAATCCCAATATGAGCAGATGCCAATATAGTGCGTCTAATTTGTTGTAGACTTCTTCAGTAATATAATAATCATATAGCCAGTCAATTAGAGTAATCTGTCTTCTTAGGATCAAGATTGCGATAGTAACTAATGCCAAAATATAAAAAAGAAAACACTTTCTCATACTAGCGCGTCTGGCTTTCACGCATTCTTCAGGGGACAGGTTCCTATATTTGTCAGTCATTTTTTCTCCTTGGGATCACATAATAATTCATCAAACTACTATAGTATACACTCCTATCAGCAAAAATGATGCAACTCTTAGAGTGGCTAGCAGGGTTTACTATTTCTTTTAAGTGCCATAGCCAGTGGGAGAAATAGGGTACAGGAAATATCTGATTATATTCGTGAAGACAAAAGTAAAGTTTCAAAGTATTTAATAACCTTGCAGACAATGCGCCTTGTAGAAAAGAAGGTTCCTTGTGGGGAAGGAGCTGGAAGTCGTAAAGGAATATATAAACTGACGGATAACTTTTTCCGTTTTTGGTTCAGGTATGAATTTACTAATAATGCATATTACGAAATGCTTGGTGCTGATGCTGCTTCAAAAGAAATTATGGAGGGAATATCGGATTACATGGGGGGATGCTTTTGAAGGAATATCCACAGAATATTTTGTGAGAAAGGCTAAAAAGAAGGAACTCCCTTTCATACCATATCATAGGAAAATGGTGGGGGAATAATGCGCATATCAAAGCACAGGACGATGTGGACATACTTATGATAGATAAGACCGGTAAGAAAGGAATCTTTGTAGAGTGTAAATTCACAAATTCCAAAATGCCACATTCGGAGTATGAAGATTTAAAAACAGCAATGTTGGCATTTCCTAACATAGAAGAAAAGTATATATTTTTTGTTAGCAAATCAGGATATGAAAAGTCTGTGGTTAGGCATGCAGCGGAAGATGGAGCAGTATTGCTGGAACTTGATGATTTGTTTAAGATAAGCTAGAGGAATATGTGAAAGAACTCGACAACTTCAAATTTGTAGACCTAATTGAATATTGAACGTTACATAGCAGTTATCTCAATCGAGGTAGCTGCTTTTTGCTTGCTTTCAAAAAAGAAAAAAATTGTAAGTTTTGAAAGTGAGACCTGTATGAAGATTATAAATATCGTGCGAGAAAACCCCTTCCGATGAAGTCGGTTGTGGGATGAATCGCACTAGCTTTTCTTTTTGTATTTCCCCGTCTTAATGTATTTGCGTTTGTGTTCCTCTGTTCGTTGATCTTCAATGTATTTCTTGACAGTATCAAGAGAAACACTTCCGGTAGTGACACAGAAGTAACTTGCACTCCAGAAGGGTGAATCTCCCCATAGGTATTTCTCAAGGTGTGTTCTATATGTATTTCGCACTTCTTTGGACAGCTGTGATTACTTTTTTTCTGTATTTAGTCACGAAAATTACATGGTATGTGAGTTTGTATACGGAATGTGAGCCTCTTCTGTACTCGTTCAGAATATCTGATTCCAGCATCGATCTCTGCATAAATTTACTCCTTATGCAAAGAGAACATATGTTTGCACTTTTCTGAAAAGTGTGCTATAATACTAGCTATAGAATACTGCTAAGGAATTTACAACCGTGTACAGAACAAGGCAATACAGGATAAACCAAAACCACATACTCTATGATTATTGCAGGGATATCTGCAGATCATCAGCCATTCTGTACAACAGGGCAAATTTCATCTTAAGGCAGTATTCGTCTGCAGTAGATTCAATGGCTTTGTTCAAGCCTCTTTTCCCAAATCAGATGATGGTTTACAGGCTCGTTAGGGATAGCCTTTTGGGAACCAAATATCTTGGTGACAGCAAATGGCTCTCATATAATGCCCTTGATCATCTGCTAAAGGTTACAAGGGATAAGGCATACTATGCCCTTCCGTCACAGGCTAATCAGCAGATATTGAAACTTCTTCTCAGAGACTATAAGTCTTTCTTTGAAGCTGTAAAAGTATATGGCAGGAATCCTGGGGCATTTACTGGTCGCTCCAAGATGCCGGGATATATGTCACAGGGATCATTCAAGACAGCTGTCCTGACTAATCAGATATGCAGGATCAAGGATGGGTATCTAAAGTTACCGGGGACAAAGGATAGGCTGTCTCTTGGCCAGCTCCCTGAAGAAGTGTGCCTTAAGGAAGTACGTATAAAGCCCAGCGGAAACAGCTTTGTTCTGGATGTAGTCCTTTCAGTGCCTGATAAAGGGATAATCCCCATGGCTGATGAGGATATCCTCACTGAGCTTTCAGAGGTAGCGGATCTGAAGGACCTGAGGGTGATGGCTATCGATCCAGGAACAGACAACATAGCTGCTGTAGCGAACTCTTTTGGCGCAAGACCATTTGTGATAAAGGGAGGCGTGATCAAGTCAATCAACCAGTTTTACAACAAAGAGATGAAAAGACTCTCTTCCTGTGCCATGACATGTAACAACAGGTACAGGACAAGAAAGATGAATGCTCTTACTGAAAAGAGGAACAGAAGGATAAAGGATCAGTTTCATAAGGTGAGCAGACAGCTTGCAGTCCATGCAAGGGATAACCATGTAGATGTAGTAGTGATGGGACATAATACATACCAGAAGCAGGAGATAGGTATAGGACATGTCAATAACCAGAACTTTGTGCAGATACCAATGCTGATATTTGCAGACATGCTCAGATACAAACTTGCTGAATATGGTATAAAGTTTGTTCTCACGGAAGAAAGCTACACATCAAAGGCAGACTATCTTGCAAAAGACTATATCCCTGTGTATAAAAACAGTTCAGGAAACCACTTTTTCTCAGGAAAGAGGATACAGAGAGGACTTTACAGGCACTACGATGGTACAATAACAAATGCAGACATAAATGGAGCTGCAAACATTTTAAGGAAAGTATTCCCAAAGGTAAGCCAATGGGATAGGGGCATAGTGGACATGCCCTGTTCTGCAGGATGCATAGAGCATCCTACAGGTTCATGCCGCCATGCGGCATAACAGAAACCCTTTCCGACGTGGAGTCGGTGAGGGCAGTTCATTGAAGAATTTTGCAGAGTATATGGGAAGAAGGGGGTATGAAATGAATCTTAGAAAACTTGGTATATTTGGATTGATTAGCTTACTTTCATATACAGCAATGGTAGTATTTTCGCCTTTAGCGTACCCCGGATATGAATGGATGAGTATGGCAGTCAGTGATCTTACGGCAGAGGGAGCTCCTTCATTACAGTTGGCAACGAGACTTAACGCATTATTTGGACCTTGCGCTGTTGTTTCCATTATGGCAGTGTGTGTAGCAATTTCCGGAAGCAAGTCAAAACTGTTTAAGCTCGGTATATATTCGTTCGCTGGTATGGAATGGATTTGCAGCGTTGGGTATACAATGTTTCCTTGGGTTGCTGATGAACCTAATACTAATCCTCAGAATTTGTGCCATCTAATTGTTACTGTATTAGTTTTTGTTCTATCTCTTGCAGCACTTATAATGATTTCTATTAGTGCCAAGCATGAAGGCGTGAAATCTCTGGGGATATGGGCAATTGCATGTCTGTGTGCGATGGTTCTCGGACCTGTAGGAACAGGACTTTTCCCAAAGGCTGTCTTTGGTATTTTTGAAAGACTTAGTACATTTTCTGCAGTTATCTTTAATGCTGTGCTAGGAGTGTATTTATTGTCTGGAAAGTTTGACAGACAAGAGGAATAAGAACAAATGAGATGAATTCATAACTTTTATTGACTAAGACAATCGGTATTTAAGGAGAGATGTATATATGAGCAAAATTTTATTTTTGACAAGCAGCCCTTTCACAGGACGGGGACTTCCTTTTAACACGGAAAATGAATTTGTCAACCGAATGCAGAAGGCCATGCATAAGTATAATAAGGGGCTTTTCATAACTGCATCACCGGATGATTATGATGAAACAGATGGTTTTTCATTTGGAATAAAATATACGGCAGAGATTTCAGGAATGGAGTTTGAGTCTTATACAGTTTTAGATAGACGGAATCAAAACGATGCTGCGAAGTTGGTAAAGAGTAGCAATTTTATTATCTTGGGAGGAGGCCATGTTCCAACACAAAATCGATTCTTTGGTGAGATAAGGTTAAAGGAACTCCTTGAGGATTTTGATGGCGTGATTTTCGGAATTAGCGCCGGAAGCATGAATAGCGCGGAAGAAGTTTATGCACAGCCGGAACTAGATGGCGAATCATTAGATCCTAATTATGTGCGTTTCATTCCTGGATTGGGTCTTACAAAAACCAAGCTGCTTCCTCATTACCAAGATACAAAAGACAGTTGCTTAGATGGTAAAAGACTTTTTGAAGATATTACGTATCCGGATAGCATGGGGTATACTTTTATTGCAATCCCTGACGGAAGTTATCTATATTCTGAAGATGGTAAGGAAGAATTAATGGGAGAGCATTTTGTCATTAGCGATGGTGGTATTGTATGATATGCGCAAATTCAAGTTTATCTGCGCGTTAACAAAGATAATGTAGCGTCACAGAAGGTAATGATCAAAAACGGTGCCTATAGAGCAGGAGAAGATGAAGAGCATTTCTTTATGAGAATAAGAAAAACTTCACCTAAGCAGATGCAGCTTATACCGCACTTAAAGAGTATGAAAAGAATGAAAGAAAGAACGATAAACCGGAAGATAAAAAGGATATAGAAATGGTATGAATAACAAAAAGGCACTAACGCTCTATTTGGTCGGAGCATTAGGACAAATTATCGTCGTATGCGTAATTGCCTTTGTACTAAGACGATATGGAGTAGAGGTGGGGTATGCCACACCGTTAGGATGGATCATCATTGCAATTGGTGGTATTTCTTCAGCGTTATGGGGAGCCATTATTTCAATAAAATATCGAAATACAGGTTTTAAAACCGTAATCTGTGATTTCTTCAGGATAAAACAAAGCCCTCTAAATTACAGTTGGATGATTTTGTTCTTATGTTTGGATTTTCTTCCGGTTGTATTCGGAGGGAGGATATCAATAAGAGTGTGGTATCTGCCGATCATAATGTTTTTCAAGCATATAGTACTAGGTGGTATAGAAGAAATTGGCTGGAGATACTTGTTTCAACCGCTTTTGCAGGAAAGGCTGCACTACATTTTAGCTACGATAATCACATTTTTCTCGTGGGGATTATGGCATTTTTTGTTTTTTTATCTTGATGGAACACATGCTGATGTGATCCCATTTTTAATTGGTTTACTTGTAAATAGCTTTATTCTTTCAGCGTTATATGTGAAAACAAATAACCTTTGGATATGTGTAATGACGCATTCCCTGATTAATGTTTTTTCACAACTTGTAACTGGAGGTAATCAATATGTAGGCTATTTCAGTAAAGTTGTTATTATAGTAATCGCTATTATGCTTGCTACTAAAACAATTAGGAAGCTTAAACAATATATTGGGCTTTTCATACATTCGAGGATATACAATGGCAAATAAAGCATTAATTTACATTCATGGGAAAGGCGGCACAGCCTCTGCTTCAGAGCAGTTTAAGTCGTTTTTTCCAGATCATGATACATTCGGCTTTGACTATAAATCAGATAATCCGTGGGAAGCAGAAAGTGAGTTTAAAGAGTATTTCATAAGGTTATCTGAAAAATACACATCTATTACTGTTCTTGCTTCCAGTTTGGGAGCTTATTTTCTGATGATTTCCGGTGCAGGTGTGATGATCCAAAAGGCGTTTTTTGTTTCTCCTATTGTAGATATGGAGCGCTTGATACAGGACATGATGAAGTATGCAAATGTATCAGAAGATGATTTAAAAGCTAAAAGCACAATCCATCTTTCTGATGGTGCAGTCCTCTCATGGGATTATCTTGTATGGGTAAGAAATCATCCAATAGTATGGAATGTACCTACTTTTATTTTATATGGTGAAAAAGATCACTTGCAATCGTTAGAAACAATGCAGACATTTGCAGAAGCAGTAGGTGCTGATTTAACAGTAATGCTCAATGGAGAGCACTGGTTTCATACAGATGAACAAACAGAATTCAGAAATAGATGGCTGCTTGATAAGAGGAAAGGTAAAAATGAATATTGATGTAAATCTTAACATTCACTATACAGCTCCAGACTATGTTTGGGATAAGATTGGTAAAGTTTATGAATCTATGCCATACTGGGTAGGAAATGATAATGGCCCTTGTTGGAAAGGCGAAAGCGTGGATCTTTGGGCTTCTGTTGAACCAAGCGGGATACAGATTGCTGGCGAGATGCCACAAGACATCTGGGAAGAATGGTATCAAAATCTTAAAGATAAGCTCACCAATGTTCTTGGATATGATATCGGAGAGCCGGAAGATGGCTTTGAATTTAAGTATGATTGGGAGAATAGGATATGAGTGCTAATTTACTTGTTTTTGAAAAAGAAAAGGCTCCAAAACTATTTTGAGCTTAAGGAAGAGTTTCCTCCGATGAATGGAAAGTATGCTCCTGATGATGCATCTCTTGAAGCGGATCCGAATCTTGAGAAAAGACTTACGGATTACTGCATAGATGAGGATCTTATCTATATGGCTTTTGCCTGGTCAGTTGCAGATGAAGCTGGAAATAAAGTAAAAGAGCTTGCTTTTAAACACGGGCTTGGATTTTTCGATATGTTTAATGTATATCCGGATAAGGATACTATCATAGAGATACCACAGATAGCTCCTGAAGAGATTGATGAGTATTCTGATGAAGAAAAGCCAAAGAAAGGGATCTTTTTAAAACTTTTTGGAAGAAGATAAATGGAGAGAAGGCAATGAAATGTGTTAAATGTGAGTGTGAGATGATCCAGGCAGAACTTACTGGCAACAATATATATCCACTATTCCTGAAGAATAAGAGGAACGGTATCATTGATTCAGAAAAAAGGGCAGATGTTATTTGCTATGTATGCTCTGAATGCGGATATATAGAGCTTTATGCCAAGGATCCCAAAAGGCTAAAAGCTTAAAAGGACTGGCATTTAGTGGGCCAAAAGCCACTAAATGCCTTTATTTGTGTAGCATCTTTTAATAAACCCCCTGCTCTGCAGGGGGATAACAGCTGCTTCAGCTTACAGTAAAAAACCTCCCGTGATAGAATTACTTACGGTTCGCCAACCAAAGTAAAATCACAGGAGGTAGTCCAAAATGGACATGAATAGTTTATCACACACAAAATGGGAGTGTAAGTACCACATAGTATTTGCACCTAAGTTCAGGAGAAAGGTTGCATACGGTCAGATCAAGCAGGATATAGCAAATATTCTCAGTACATTATGCAAGAGGAAAGGTGTAGAAATTATAGAGGCAGAAGTATGCCCAGATCACATACATATGCTGGTAAGGATCCCGCCGAGTATGAGTGTATCAAGCTTCGTAGGCTACTTGAAAGGAAAAAGTACGCTTATGATATTTGAGAGGCATGCAAATCTCAAGTATAAGTACGGCAATAGACATTTCTGGTGCAGAGGCTATTATGTAGATACTGTAGGTAAGAATGCAAAGAAAATTGAGGAGTACATAAAGAATCAGTTAAAAGAGGATTTAGAGTACGACCAAATGACACTAAAAGAGTATATTGACCCGTTCACGGGTGAGCCGGTAAAGCAAAACAAATAAAAATGAGCCCAGGGGGCTCTGTAGGAAAATGATGTTGCGGCTGGCGAACCATTCGGCGAGTCTTTAGACTCAGTGCCGGCAACAGGCCCTTATAGGGCCAGAACAAACCACCGGCTAAGCCGGTGGTTCTGATTATGCGCAAAAACAAGCTATAGTTGTATTTAATACTTCTAGGGGAGGTTTTATGGGGAACGTTAATTTGAAAACAGATAGTAAATTACCATGGTGGAAGTTAGTTGTTGGGATTCTTGTGGCACTTTTAATTATGGTTGCCGCACAACTATTTTCGCAATTTGCCGCAATACCAGCAGATCTTTTAAAATTGCCTGTAGTAGTTGCGATAGTTTGTCAGGCTGTCGCTTATGTGGTATTAGCTTTTTTGGGGCAGAAGCTTTTGATTGAAAAGTTTTTTAAGATATCCATAGATAGTATAAGAATAAAGAAGCCTGGAATTAAGATGATTTGTATTATTACTGCTGTGTTACTTCCGGCTATTGTTATAGCAATATATATGATGATGCCAGGGGAATGGACAACGCTTACTTTATCTAACGGTGAAAAGATCAGAATAGTAGTAGGAGCACTCATTTTTCAGAGCATAGCGGCTGGAATAGTTGAAGAGTTGACTTTTAGAGGTGTTATATTTGGCTTACTTGAGAAAAAGACTAATACAGTAGCAGCGGCTGTGATTCCATCGGTGATCTTTGGTATGATCCATTTTTCTAAGGGCATGAGTTTGGTTAGTTTTATTCAGCTCGTGATTGCTGGAACTTTTGTAGGAGTTATGTTTTCATCTATCTGCGCTTATACAGATAATTTCTGGAACAACGCTTTGGTACATGCGTGTTGGAATGCCACAACTTTTGGAATAATGCATATAGATACTGCACCTAGTGGTGAAGCTCTATATACCTATGTACTTAAGACAAAATCTATGCTCATTACAGGTGGAGATTTTGGAATAGAATCATCGATTATAGCTATTATGGCTTATGCAGTGGTTATAGTGGTTTATGTTTTGTTCATTAGAAAAAAGAAGCGTGATGTAGCAAAAAACTAATGATTTTCGATACACATTGGGTATATGTATAATAGGGATTGAAAGAATGTAGGACAGTTTGTCTTCTTGTTGTAAAAATAGAGGATGACTATCTCATGGGATTTAATCATTGGAGAAAAGCTTGGGAAATATTTGGCGGTTGTCCAGAGCCGGGCGAGGATTTACGGACCACAATGATTCGTGAAGCAAAAGAGGAACTTGGGATAGATTGTGATCCGGAATGGTTGGGGCTTGCTCACTTTGAAATACAGCCAGATTACTTTAGTGATAAGATCCGAGAAGAGTATGGAGCTATTTATGGCTTATCTTTAGGAAAAGAGTATTTGTCGCAAATAGAAGAATTGCGAATCGATAGAGAAGAGATTGAAGAAATAAAGCTATTAAGAGAAATTACTTCTGGTGAAATCAGAGAACTGGACAGAAAGTTAACTGAGTTTTATTAAATACAATCGGTATTTGTAGGGGAAATAATGAGAATCGGAGTTATTCAAGCTAGTTCACAAGCGGCTAAAAATCAAATAATATATGATGCTGTATCAAAATATGCTCCAAAGGAATCGGAGGTTATAAATTTTGGCTGCACGATGGAAGAAAATGAGAATTATTCTTATATAGAGATTTCTATTCTTGTAGGGATATTGCTGGCAAGTAAGGCTGTGGATTTCATTGTTACGGGCTGTTCTTCCGGACAGGGGATGATGCTTGCTTGTAACAGTATACCAGGCGTCATTTGTGGATACGCACCTACACCGAAAGATGCCTATTTGTTTGCTCAGATTAATAATGGAAATGCGATATCATTGCCCTTAGGTGAAGATTATACATGGTCAGGTACTGAGAATCTTGAAAGAACAATAGAAGCTCTTTTTTCAGAACCATTTGGGCAAGGATATCCTATAAGTGAGGCTGAGAGAAAGATAAAAGATACTGAGAAGCTTAAAGAAATAAGAAGAATAGGTCAGGTTCAGTTTGAAGAATTCATAAATGTGCTGGATGTATCATTGCTTGAATCAATCAAGAGGAAAAAGGATGTAATTCAGAACGTAATGGTATATGGGAAGAAAGAAATAGCTGATTTAATAAAATAAGCCAATTCAGGCTTGTCGGGGAGATGATAGAAAGACAAATGATTTTCCCTACAAGTTAGAAACATGTTATTCTTTTATAGTAGATTGGACGTCGGGATAACGTATCATGAGCATTTTAGAACACATAATTGACAAGAGAGAGCAAAATGAAGCGGAGAGTAAAAATGTTTTTGAAAGCAACGGGTATTGCTATTGTTTCCTTTATCGCTATTGTTTTAATAGCACATTTCATTGGCAGAATGATCAATAGCAGGACTCCCAAAGGCGGCATAAATGAATCAATGTATGTAGATATAAACGGCACGAAGCAGTGGATAAATATCTACGGACAGAGTAAGGATAACCCTGTTTTGCTGTATCTTCATGGTGGACCGGGTTCTGCTACTAGTACCATAGATTATGCGTTCACTAGAAAGTGGAGTGATGTTTATACAGTCGTAACATGGGATCAGCGTGGCTGTGGAAAAAGCTATGCCAGTTCAAAGACAGATACTATAACCGCAGATTTAATGATTCAGGATGGCAAGGAAATGACTGAATTCCTGCTTGGATATATGGACAAGGAAAGGATTACTCTTCTTGGGCATTCATGGGGATCACTGTATGGCGCAAACTTAGCATTAAAGTATCCCGAATACTACGAAGCATTTATTGGAGCAGGACAATTCATAGATCCTATGGAAAATGAAAAAAGACTTTACGAAGCGGCACAGAAATGGAGTAATGGCGATGAAGAGGGCAAGGCAATACTTGCCAAATGGTCTCCTGACAACGAATACTCGATGGAAGCTTTGAATGCGAGAAATGCTACTATGGAAAGATATGGCTATGGCATGATGAAAGATGGCACGGATTACAATACCTTTACTACAGTGCTGTTCAATCCAAACTATACGATAAAGGATTATATCGGATATCTGAGAAAAGGCAGCAAAGGGTTCAAGCCGTATCTGGCTTTCTGGGAAAACGAATTGTCAAAGCTGTCATTGTTAGGCAGGTACGATTACAAAGTACCCTACTACAATATAAACGGAGACATGGATTATCAGACAAATTTTGAGCTTGCCAGCGAATACTTCGATGCTGTTAACGCGCCCCAAAAAGAAATGTTTGTTATGAAAAATGCAACTCATGGACTGCTTGAATCACGTTCAAAAGAATTCTCGGAGATGGTACACAAAATAGCGGAAACGCAGAAATAGAGAAGTATCTAATATTCCGACATAACTGACTATGGGAAGTGGAATATCAGATTAGAACTAGACAATATGTAATGACCTCCACTATGTAGCAACGTGGATTTACCTGTATACTAAAGATGTTGAGTCAATGGTAACAGGGATTACCGCATACAAAGGGAGGTCACTAAATGAATAATATCACAGTTTACGTAGGAATGGATGTACATAAGGAAAGTTTTACTCTCTGCGATTATTTAATCGAAACAGAGAAGGCGTCTCATACAAGGCGCACCCACGCTGATTACAAGGAAGTCCTAAAATATCTGGAATTCCTTAGAACCATCTACGGAAATGATACAAACTTTATATGCGGTTATGAAGCCGGATGTCTCGGCTATACTTTATATCATCAGTTAACTAATCATAACGTTAACTGTGTGATACTTGCACCAACCACTATGCTTGAACCGCGTAGTGGCAAAAGAATTAAAACTGATAAACGTGATGCTGAATTGATTGGCAAATGTCTGGCTCAGCACAATTACAGTCCTGTTCATGTTCCTACTTCTACAGATGAAGAAACAAAAGAGTTTCTCCGTATGAGAGATGATCATAAGCTTGCACTCAAGAAAGTGAAGCAACAAATACTTTCGTTTTGTCTTCGCCACGACTATCGCTATGAAGGAAAAAGTCACTGGACAGAAGCTCATGTGAACTGGTTAAAATCATTAAAGCCTGAGGCACTGTATAAAGAAATACTCGATGAATATCTGCTGACCTACATAAACTTGAGAGATAAGCTTGAACGTTTAGACAAGCGAATAGAAGAACTTGCTTTAAAAGATGAATACAGAGAGCCTGTTAAAAAACTCTGCTGTTTCATCGGGGTTCAAACTCACACAGCACTATCTGTATTGGTTGAAGTAGGTGATTTCAAACGTTTTGCATCAGCCAATCAGTTTGCTGCATATCTTGGACTTGTGCCTGGTGAAGAATCCAGTGGTGATGAAAAGTCAAGGCTTGGAATCACAAAAGCCGGAAATCGTCATGTTAGACAGCTTCTTATAGAATCATCCCAGTCATACAGCAAAGGACAAATCGGACATAAATCAAAAGCACTTAAATCCCGTCAGATTGGCAACTCACCTCAAGTCATTGCATATGCTGATAAAGCTAATGAAAGGCTAAGACGCAAGTTTTACAAAATGGTTCTTGGTAAAAGCAAGAAACACAATGTGGCTAAAACTGCAATAGCAAGAGAACTTGCCTGCTTCATGTGGGGCATGATAACCGATAATATAGCATGA

Protein sequences of DBSCAN-SWA_1

>NC_014388|71646:111667|87133_89143_+|WP_013282405.1|DBSCAN-SWA
MYYAAVAFLAFTVNIILNWNSFKNAWKKTDARDTKKLSLIRYGHFLLAANCFFLTEICWGIIYDHHDVPELFPIVYSITVFYFLFMLLTMLTWARYIVAYLNKGNFRSKILTIGAWIMFLLGIGSLMLNRFYHFIFSYNEAHEYIPEKGSLATFIFVLAFYAILSMHMLIAAYKTKGSQKIRYMAVAYTSMALGIFMFLQILTSFLPLYVIGLLIAICIVHSYVEAGEKKEKEIQDHITSIMAEDYEAIYYFDIETGEYIEFSRSQKYSFLDVTYIGKDFYKESLDNIEKTVHPDDKEYARSLFNKEAMIKNLEGKRSFSYKYRLMVDGYPRYFLFTYRGAGDDKHIILYEKDIDDELMAEKKIHENQEKSITFSRIAESLATNYDAIYYVDAVDSSYVSFEANDIFGQLQVSQLGKEFFEECYSNIPKIIHEQDRNRVVEFLDRDKMITALDNHRSSSIEYRLLVDGSSQYLRMIARRSSDRSHFIICVENIDDEVRREKQRLKELKTEKELARRDELTGIKNKYAYKELEESIQGNMDHGLDYLPYALIVCDANDLKKINDTLGHVAGDEYLKAAAKLLCYTFVHSPVFRIGGDEFAVFLRGDDYYIREELMEKLRNQVLENQKAGNGVVLASGMSEYNPKTDTVVSDVFERADKAMYENKRKLKGQ
>NC_014388|71646:111667|72651_72888_+|WP_013282400.1|DBSCAN-SWA
MGLIWGLILGAIAGLIASKLMNENSGLIKNILLGVGGGFVGGLVFKLIGFAATGLIGSLIVSIVGACICIWAGRKLFK
>NC_014388|71646:111667|108186_108534_+|WP_013282428.1|DBSCAN-SWA
MGFNHWRKAWEIFGGCPEPGEDLRTTMIREAKEELGIDCDPEWLGLAHFEIQPDYFSDKIREEYGAIYGLSLGKEYLSQIEELRIDREEIEEIKLLREITSGEIRELDRKLTEFY
>NC_014388|71646:111667|93511_94006_+|WP_013282409.1|DBSCAN-SWA
MVKEIVGDLLRQPVDIVAHQTNCAGKMGAGVALAIKKQLLTSDAYEKYKSICKEQGSDLLGKTQLLEAPDGRIIANCFGENIPTGKGRDTDYDALMHSIAKVRNYAKRSDPMLSVGVPGLIGCGLAGGDWRIVRDMLYKLFGGEGEPDLYICYLDEKEYRKWNY
>NC_014388|71646:111667|78408_78816_-|WP_026663115.1|DBSCAN-SWA
MELKNCATCHRVFQYPGYGYILCPECRRTDEAQFQLVKKFLDQYPGAEGKEVFLATGVPINTLIKWVREERLISSNAVNLGAVCDRCGKPVSSGKLCPDCRKDIVDKFKETEAEDIEKVEKILPKSKNNGMRFLQ
>NC_014388|71646:111667|104864_105485_+|WP_042258315.1|DBSCAN-SWA
MANKALIYIHGKGGTASASEQFKSFFPDHDTFGFDYKSDNPWEAESEFKEYFIRLSEKYTSITVLASSLGAYFLMISGAGVMIQKAFFVSPIVDMERLIQDMMKYANVSEDDLKAKSTIHLSDGAVLSWDYLVWVRNHPIVWNVPTFILYGEKDHLQSLETMQTFAEAVGADLTVMLNGEHWFHTDEQTEFRNRWLLDKRKGKNEY
>NC_014388|71646:111667|110548_111667_+|WP_013280040.1|transposase|DBSCAN-SWA
MNNITVYVGMDVHKESFTLCDYLIETEKASHTRRTHADYKEVLKYLEFLRTIYGNDTNFICGYEAGCLGYTLYHQLTNHNVNCVILAPTTMLEPRSGKRIKTDKRDAELIGKCLAQHNYSPVHVPTSTDEETKEFLRMRDDHKLALKKVKQQILSFCLRHDYRYEGKSHWTEAHVNWLKSLKPEALYKEILDEYLLTYINLRDKLERLDKRIEELALKDEYREPVKKLCCFIGVQTHTALSVLVEVGDFKRFASANQFAAYLGLVPGEESSGDEKSRLGITKAGNRHVRQLLIESSQSYSKGQIGHKSKALKSRQIGNSPQVIAYADKANERLRRKFYKMVLGKSKKHNVAKTAIARELACFMWGMITDNIA
>NC_014388|71646:111667|105858_106173_+|WP_013282425.1|DBSCAN-SWA
MNGKYAPDDASLEADPNLEKRLTDYCIDEDLIYMAFAWSVADEAGNKVKELAFKHGLGFFDMFNVYPDKDTIIEIPQIAPEEIDEYSDEEKPKKGIFLKLFGRR
>NC_014388|71646:111667|102461_103106_+|WP_013282419.1|DBSCAN-SWA
MGRRGYEMNLRKLGIFGLISLLSYTAMVVFSPLAYPGYEWMSMAVSDLTAEGAPSLQLATRLNALFGPCAVVSIMAVCVAISGSKSKLFKLGIYSFAGMEWICSVGYTMFPWVADEPNTNPQNLCHLIVTVLVFVLSLAALIMISISAKHEGVKSLGIWAIACLCAMVLGPVGTGLFPKAVFGIFERLSTFSAVIFNAVLGVYLLSGKFDRQEE
>NC_014388|71646:111667|96091_97732_+|WP_013282412.1|DBSCAN-SWA
MKKRSIRLAAISTAAVMLLSACTSTGNVVNEDGASGVSIEAIADTSNAENKSGSDTATTFPVTVVNHPISSSQDGKVLCTGSYPEIVLSDEYKEKYPKLSENINNYNETNSFGATSNISEYAAWALEDTYYTEGYFDTKTADIVRFDDHLFTIFEISSSFTGGAHPNHYSYATNYDPATGDIVRLDKVLDDSSLLYDGIRTELEKNYPGIMEEVDSFYFPEEGQDPDQFVQKLRDDTYTWTIDDKGLNIFFSPYEIASYATGDLQVVLSSKEYPDLVKADYMLDQPQDLDSIVNHTDADTTEVAPSEDEPDPESVSVSNPTWKYYKAADAIVPAGNHLTLTKTNEEKSDYLDSYAWAEANDLQTEMLTHEDDNYFYNGTNEVEYANSFQGIDIYDTEMDTMYYSFDLSELCDGPDYEQEKVSAVHQFIRYATIVDNILYLEIGHLGYASEEPESSYIVAINLETNELIFRSEPLVANGSNFKIVDDTIICGYGFTSEPDYIYLLDRFTGEKYDAIKINSAADQFQVKGDTLYVATYNTAYEFTITH
>NC_014388|71646:111667|108561_109179_+|WP_013282429.1|DBSCAN-SWA
MRIGVIQASSQAAKNQIIYDAVSKYAPKESEVINFGCTMEENENYSYIEISILVGILLASKAVDFIVTGCSSGQGMMLACNSIPGVICGYAPTPKDAYLFAQINNGNAISLPLGEDYTWSGTENLERTIEALFSEPFGQGYPISEAERKIKDTEKLKEIRRIGQVQFEEFINVLDVSLLESIKRKKDVIQNVMVYGKKEIADLIK
>NC_014388|71646:111667|103173_103863_+|WP_013282420.1|DBSCAN-SWA
MSKILFLTSSPFTGRGLPFNTENEFVNRMQKAMHKYNKGLFITASPDDYDETDGFSFGIKYTAEISGMEFESYTVLDRRNQNDAAKLVKSSNFIILGGGHVPTQNRFFGEIRLKELLEDFDGVIFGISAGSMNSAEEVYAQPELDGESLDPNYVRFIPGLGLTKTKLLPHYQDTKDSCLDGKRLFEDITYPDSMGYTFIAIPDGSYLYSEDGKEELMGEHFVISDGGIV
>NC_014388|71646:111667|91733_92162_+|WP_013282407.1|DBSCAN-SWA
MNNRLRQIGFLIQGWLSRALYGRNGFDNLARTCNAIALILLVINIFAQSVVVYFIWVVLFGYSLFRVYSKNITKRYAENQKFLQITESPRRYANLMRLQWRDREVSRYYICKKCHQQIRVPKGKGRIEIRCPKCGERFIKRT
>NC_014388|71646:111667|85178_86936_-|WP_013282404.1|DBSCAN-SWA
MSTLSKRIISCIACVGLVAFCIWGSTYVVEHEGHQYDGAADGFAGEIKVSVFVEDGTITDITYQTEGETPSIGGSAIKALRTKILKTQNTQIDAISGATYSSRGFLSAVNTALAEAGIVADGSHKGNAASEDYEATADVVVVGGGGAGMTAAITVAENGKKVILLEKSDILGGNTSRASSGMNAAETHYEKEQGVEDSVDLFVEDTMKSGKEINDPELVRTLAENTSEAIDWLDKENAPLSGPLGTMGGLSAKRTHRPTDAEGNVTSVGNFLVSALGVRLDELGVEIITGATVNKIIMEDGKASGVSGIGEYGENITVHANAVIVATGGFGGNMDRIVALRPDLAGYISTNVATASGDAIDFLGEVGADFVDLEQIQLHPTVIPTDGALVGEALRGDGAILVNREGVRFTNETGTRDAVSAAEVAQTGGNVWLIANEEMYEGSAVIKKLDKSGYLVKGDTLEDLAAAMEFDSNATSALLKTVETWSGYVASGTDADFSRDIGTPLTDLSSGPYYAVNVGPGIHHCMGGVKINTDAQVISTDGTPIPGLYACGEVTGGIHGANRLGGNAVADIVVFGRIAGENASK
>NC_014388|71646:111667|109325_110381_+|WP_013282430.1|DBSCAN-SWA
MKRRVKMFLKATGIAIVSFIAIVLIAHFIGRMINSRTPKGGINESMYVDINGTKQWINIYGQSKDNPVLLYLHGGPGSATSTIDYAFTRKWSDVYTVVTWDQRGCGKSYASSKTDTITADLMIQDGKEMTEFLLGYMDKERITLLGHSWGSLYGANLALKYPEYYEAFIGAGQFIDPMENEKRLYEAAQKWSNGDEEGKAILAKWSPDNEYSMEALNARNATMERYGYGMMKDGTDYNTFTTVLFNPNYTIKDYIGYLRKGSKGFKPYLAFWENELSKLSLLGRYDYKVPYYNINGDMDYQTNFELASEYFDAVNAPQKEMFVMKNATHGLLESRSKEFSEMVHKIAETQK
>NC_014388|71646:111667|100999_102400_+|WP_013282418.1|transposase|DBSCAN-SWA
MYRTRQYRINQNHILYDYCRDICRSSAILYNRANFILRQYSSAVDSMALFKPLFPNQMMVYRLVRDSLLGTKYLGDSKWLSYNALDHLLKVTRDKAYYALPSQANQQILKLLLRDYKSFFEAVKVYGRNPGAFTGRSKMPGYMSQGSFKTAVLTNQICRIKDGYLKLPGTKDRLSLGQLPEEVCLKEVRIKPSGNSFVLDVVLSVPDKGIIPMADEDILTELSEVADLKDLRVMAIDPGTDNIAAVANSFGARPFVIKGGVIKSINQFYNKEMKRLSSCAMTCNNRYRTRKMNALTEKRNRRIKDQFHKVSRQLAVHARDNHVDVVVMGHNTYQKQEIGIGHVNNQNFVQIPMLIFADMLRYKLAEYGIKFVLTEESYTSKADYLAKDYIPVYKNSSGNHFFSGKRIQRGLYRHYDGTITNADINGAANILRKVFPKVSQWDRGIVDMPCSAGCIEHPTGSCRHAA
>NC_014388|71646:111667|81038_82892_+|WP_013282402.1|DBSCAN-SWA
MNILNVENVSKTYMSKPVLSDVSVGISDTDKIGVVGTNGTGKSTLLSIVAGVTEPDSGQIVANNGLRISYLPQNPVFDMDKSLLENIADTIYAGGDHWDKMGEIKANLAKFGIDDPECNPSILSGGQKKRAALVAAIMTPSDLLILDEPTNHLDSGMIEWLEDFLQHFRGALLMITHDRYFLDEVTNQILEIDKGSVYRYESNYSGFLELKQQRLDYEQAAERKAQSLYRKDLAWMLRGARARSTKQKAHIQRFEELRDRQKPEEERFVELSSLPSRMGNKTIILENISKSYEGKKLFKDFSYTFNKLDRIGIIGPNGCGKSTFLKCIIGMVEPDTGTVEIGQTIKIGYFGQENEALDESKRVIDYIKDTAEFIRTAEGLVSASVMCERFLFTPDMQYAPIAKLSGGEKRRLYLLRVLMEQPNVIILDEPTNDLDIQTLRILEDYLDGFAGIIITVSHDRYFLDRVVTRIFAFEPDGSLYQSEGGYSDYVVHKNGLEDADAATDSGNRKKSGNASGNNSAGSNNGDDQDVKSNGKYRAPREKTKLSYKEQREYDTIEEEIEKLEQKSEELEAQIAEAATDYPRLVALSKEKEEVDAEIERKMDRYVELQDMVDSFSK
>NC_014388|71646:111667|95751_95940_+|WP_013282411.1|DBSCAN-SWA
MENLKNILRNESKNSELGDTTTKTNSVALEKTLESIGALSAVSNIRKSSLFLLKQCAFSSMT
>NC_014388|71646:111667|106560_107031_+|WP_013279565.1|transposase|DBSCAN-SWA
MDMNSLSHTKWECKYHIVFAPKFRRKVAYGQIKQDIANILSTLCKRKGVEIIEAEVCPDHIHMLVRIPPSMSVSSFVGYLKGKSTLMIFERHANLKYKYGNRHFWCRGYYVDTVGKNAKKIEEYIKNQLKEDLEYDQMTLKEYIDPFTGEPVKQNK
>NC_014388|71646:111667|80674_80857_-|WP_042258309.1|DBSCAN-SWA
MDMNNLIKDIENSKSADEALKKLSSSGIKLTDDELEMISGSNYLDTIIKILKHVKQIPCR
>NC_014388|71646:111667|92219_92930_+|WP_013282408.1|DBSCAN-SWA
MFWIIATLCAFYVKGLCGFANTLVFTSILSFGTANINISPVELLLGYPTNLIISWKERRHIDLKICIPLSLMVIVGSLGGVFFLKNADVSVIKIIFGVLVALVGAEMLVRELPQRQAKSSKLLLTIIGIVSGVLCGLYGVGALLGAYIGRTTTNADEFKANICTVFMIENTFRIILYGFYGIITLSALRQALTLAPFMLIGLIAGMLSAKIIDEKMVKRIVIIMLIVSGIALILTV
>NC_014388|71646:111667|71646_72210_+|WP_013282398.1|protease|DBSCAN-SWA
MKRLKVTFNSPVVLGFIFISFGVLALGFLTGNLSNQLLFMTYHSSLTNPLTYVRFFTHVFGHNGWEHYIGNAAYILLLGPMLEEKYGSKRIMQVIVITAMVTGLVNYILFWNVALCGASGVVFAFILLTSFTSFKNGEIPLTFILVAIIFIGQQIYDGLFLQDDISNLSHILGGVIGAVVGYRLNKK
>NC_014388|71646:111667|79172_80669_+|WP_042258375.1|DBSCAN-SWA
MGKITVDPNCRIKFNNNVDYCVGTGRLGLALTEEYLKELEFVQKMIGFSYIRGHGLFSDDVSIYHEYEENGETKVEYNYTYIDRIIDSYLKLGIRPYLELGFMPGQLASGTQTIFYWKGNTTPPKDYKKWTDMVIALLVHLKKRYGEEVTSWPIEVWNEPNLPGFWYKADMEEYFKLFKETFLAIKEYDSRFKVGGPAICGVNDAVWIKAFLSFCKREGLRPDRITRHHYTVEFPERIGHYDYSKLEDSEMRFANLKSTRDIVDSYDEFKGLPIHLTEFSTSYTPKGVIHDTNINAAYLARQLSRLGDDNEAYSYWTFGDVFEEQGVPDSLFHGGFGMVAAGNIPKPTFWTFYFYKQLKLFSDECVYRDDNAVIVKKDNGYSGILWNIDEEDEIRELLMEVTDSSDYTLITKTVDENCCNPLKLWHDIGEPAYPTHAETELIKSAAWPLTESTVISAKDGVVSSQITVNRNGVVYFTLTKRQLTSDRGYDYDKVVSYH
>NC_014388|71646:111667|94143_95679_+|WP_013282410.1|DBSCAN-SWA
MKEEKKLGLMSLILMIFTSVYGFNNIPRSYYLMGYAAIPWFVIAGILFFIPFAFMIAEFGSAFRNETGGMYSWMCKSVGPKYAFIGTLMWYTSYVLWMVNVSSGIWVPVSNILFGEDNTASWSLFGSQFLSGSRLLGLMAVIFFIIITYFDSKGLDKISTVTSIGGTAVLTINILVVVGSIVMIIARHGQFEQPFAGLESLKTPLNVSYQGSPIMILSFIVYALFAYGGIEAVGGFVDKTENPKKNFPLGIVSAALVIVVGYALLIMLVGSFTNYSDILGSEDITLGNVSYVIMSNFAASFGKAFGASQAAQVALAHGFARVYALIMLLALMGAMFTLVYSPLKQLIEGTPKELWPGKIGEISEDGMPKNAMWLQCTIVCIMVLLVSFGGNTMQQFFVILTAMVNVGMTVPYMFISFAFPKFKKMKGLDRSFVIFKSQASANIWGYVVTLTLFLANAFAIIQPALDGDFKTTFWSLGGPVVFGLAAWIIYTNYEKRLAADTKNDLENKRAS
>NC_014388|71646:111667|104089_104875_+|WP_013282422.1|protease|DBSCAN-SWA
MNNKKALTLYLVGALGQIIVVCVIAFVLRRYGVEVGYATPLGWIIIAIGGISSALWGAIISIKYRNTGFKTVICDFFRIKQSPLNYSWMILFLCLDFLPVVFGGRISIRVWYLPIIMFFKHIVLGGIEEIGWRYLFQPLLQERLHYILATIITFFSWGLWHFLFFYLDGTHADVIPFLIGLLVNSFILSALYVKTNNLWICVMTHSLINVFSQLVTGGNQYVGYFSKVVIIVIAIMLATKTIRKLKQYIGLFIHSRIYNGK
>NC_014388|71646:111667|106187_106382_+|WP_013282426.1|DBSCAN-SWA
MKCVKCECEMIQAELTGNNIYPLFLKNKRNGIIDSEKRADVICYVCSECGYIELYAKDPKRLKA
>NC_014388|71646:111667|72251_72536_+|WP_013282399.1|DBSCAN-SWA
MNNSFNHISDMENIFDEVLDAQYLIENALKEYRNLQNKVRMIEDYYSSKQWIKDFEMDERGEIPPEVKRGVLSEDGIYRMLERNKEIMKMIGDD
>NC_014388|71646:111667|107215_108091_+|WP_013282427.1|protease|DBSCAN-SWA
MGNVNLKTDSKLPWWKLVVGILVALLIMVAAQLFSQFAAIPADLLKLPVVVAIVCQAVAYVVLAFLGQKLLIEKFFKISIDSIRIKKPGIKMICIITAVLLPAIVIAIYMMMPGEWTTLTLSNGEKIRIVVGALIFQSIAAGIVEELTFRGVIFGLLEKKTNTVAAAVIPSVIFGMIHFSKGMSLVSFIQLVIAGTFVGVMFSSICAYTDNFWNNALVHACWNATTFGIMHIDTAPSGEALYTYVLKTKSMLITGGDFGIESSIIAIMAYAVVIVVYVLFIRKKKRDVAKN
>NC_014388|71646:111667|89276_91469_+|WP_013282406.1|DBSCAN-SWA
MDIRFLEKEKVFVIDTENTSYVMGISGEEGLLGHLYYGDKIDSSDVAYLWKTVEPQVNPTVDMRDRSSFLDRFPFEYSSNNVGDYRKSSIEITDSNGHTSLLLCYESHEIFGGKRAIAGLPATFGTADDSMSLEIVLADKVVGIRCILSYSIFAGLDVIARSVRLENLSDNTVYIDKVMSFTMDMDQEDYKLLTLHGSWARERWMDFREIGFGDTSIESFRGESSHQFQPFMALVQKEDSQDTGKVYGFSFVYSGNFEAGVTKSQFNSLRVYMGIGAKNFRWTLRPGEKFDAPEVVMTYSAGGLGKMTRTFHDLFRNHLIRSKYKDMERPILINNWEATYFDFDSDKLIAIAREAKKSGIEMLVMDDGWFGERNDDNSSLGDWYVNEDKLKGGLKKLVDEVNSLGMKFGIWMEPEMVSPRSKLFEAHPDWAIQIPRRTPCRSRNQLVLDITRQEVRDYIYGRIRAILTSANIEYVKWDMNRQLCDLGSLGLDKESQGELSHRYMLAVYELQERMITEFPDLLLENCSGGGARFDAGMLYYSPQIWCSDDTDAIERLVIQEGTSLIFPLSTMGAHVSDCPNHTVGRTTPFKTRGDVALAGTFGYELDITRIPEEDRADIPRQVAVYHKYNHLVRGGDYYRIASYQRNHEYDAYIVVSKDKKEALITYVQVVAKPNSSRKLLKVPGLLADVRYQLEGSDEEILGATLEKVGLSVNPLNGDYRSELIHLIARK
>NC_014388|71646:111667|97748_98669_+|WP_013282413.1|DBSCAN-SWA
MKQNTKIYTLTHTLMLLVASFFWGTTFVAQSLGAEYVGAGTYLALRTYIGIIFLLPFVLYRDKKEVNNLGLGLQELQDKRSREKQAFIKGGMLAGLFIFLASFAQQYGIAYTSVAKAGFLTTLYVVFVPIISLFFGRRFDNKLWISIALSVLGMYLLCMKGSFYLEIGDALMILSALGFSIQILAVSRYSKRIDPVKLTLAQFIIEAILATIVMFVIEKPDLSSIYSALPAILYAGIFSSGIAYTLQALGQKNLNPAIASIAMCLESVFGTLSGWIVLGQQLSLREAAGCILMFAAIVLTQFLGNS
>NC_014388|71646:111667|98711_99596_-|WP_013282414.1|DBSCAN-SWA
MTDKYRNLSPEECVKARRASMRKCFLFYILALVTIAILILRRQITLIDWLYDYYITEEVYNKLDALYWHLLILGFAVCVIVLIVVIYIHEAFFIGIMNTLCDPEKYVKAELIRCKKSIFRRLSKRNRMNIGVAYLAMKDYENAWNYYEGLVPANPYQCRNKALLCRLAGYFHDIGDDEKAAVYKTCLEGLRDSGRSNFLVELTLDDLNIEDAIKDQRYEEAKNLIAKYIKSSRVSMYTKTVYQYYLGVIAYETKDIPEAIFHLKAALEIGEKLPFAEDAKAKLDDMLHMINLSF
>NC_014388|71646:111667|82948_85105_+|WP_013282403.1|DBSCAN-SWA
MELLEQLNHAQKEAVISTEGYIRVIAGAGSGKTRALSTRFAYLVNGLGIMPGHILCVTFTNKSANEMRQRIHALTGDNDTGYINTFHGFCVSVLQEDSHAVQYPKNFLVLDNSDIDDMLKIIYEERGLSLRDMTFSSARDMFEIRKLFEEPEYYLDMLTMPLETLKDKYDQATEVKDILFYGYLYQEKKCFGLDYNDLIKFTLYIFRENPDIKLKWQKRLEYIMIDEFQDIDSLQYELMEVLAGYHKNLFIVGDPDQTIYTWRGANVKYLLDFDQNFPSVKTIMMNDNYRSTPQILYAVNSLIDKNRYRIKKDLLPTIAEGESVLCHLAPNTTEEADWITGEILVLKGLGVQYKDITILYRAHYVTRTIEEGLMKEKIPYTIYSGVQFFGRTEIKDALCYLRMLVYRDDISFRRIANVPKRNLGKRRMSFLEQYAADNKCSLYAALHENLDNELFKGTKAGKFIDLIEHFAASYEGLPVSEVLAKILNNSGYEEMLRTEGAQDRLDNLAELKQSVFEYETTCGEEVGLEDYLKHIALFTNADSDAGDQDKVRLMTVHAAKGLEFPYVFLCGMNEGIFPSRKVRTLEGMEEERRLAFVAMTRAQKRLFITEAGGNTFEGIPRYPSRFIMDIDPELLEFTEKPDDNMIKAVRKFIDNDSRHLKGAEKLNLLEKGQRVKHAILGIGTVLDINLDEESYLIKFDEMDTPRQISMKVNLAKED
>NC_014388|71646:111667|105474_105786_+|WP_013282424.1|DBSCAN-SWA
MNIDVNLNIHYTAPDYVWDKIGKVYESMPYWVGNDNGPCWKGESVDLWASVEPSGIQIAGEMPQDIWEEWYQNLKDKLTNVLGYDIGEPEDGFEFKYDWENRI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013282398.1|71646_72210_+|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_013282399.1|72251_72536_+	DUF4298 domain-containing protein	NA	NA	NA	NA
WP_013282400.1|72651_72888_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_026663115.1|78408_78816_-	hypothetical protein	NA	NA	NA	NA
WP_042258375.1|79172_80669_+	xylan 1,4-beta-xylosidase	NA	NA	NA	NA
WP_042258309.1|80674_80857_-	hypothetical protein	NA	NA	NA	NA
WP_013282402.1|81038_82892_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	6.6e-48	28.5
WP_013282403.1|82948_85105_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	1.7e-87	33.7
WP_013282404.1|85178_86936_-	flavocytochrome c	A0A2P0ZL82	Lactobacillus_phage	3.8e-53	28.9
WP_013282405.1|87133_89143_+	diguanylate cyclase	I6XM43	Pseudomonas_phage	6.8e-06	36.4
WP_013282406.1|89276_91469_+	alpha-galactosidase	NA	NA	NA	NA
WP_013282407.1|91733_92162_+	hypothetical protein	NA	NA	NA	NA
WP_013282408.1|92219_92930_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_013282409.1|93511_94006_+	macro domain-containing protein	A0A0H3V0V8	Geobacillus_virus	6.7e-24	41.3
WP_013282410.1|94143_95679_+	glutamate/gamma-aminobutyrate family transporter YjeM	NA	NA	NA	NA
WP_013282411.1|95751_95940_+	hypothetical protein	NA	NA	NA	NA
WP_013282412.1|96091_97732_+	DUF3298 domain-containing protein	NA	NA	NA	NA
WP_013282413.1|97748_98669_+	DMT family transporter	NA	NA	NA	NA
WP_013282414.1|98711_99596_-	hypothetical protein	NA	NA	NA	NA
WP_013282418.1|100999_102400_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	3.7e-59	32.3
WP_013282419.1|102461_103106_+	DUF998 domain-containing protein	NA	NA	NA	NA
WP_013282420.1|103173_103863_+	Type 1 glutamine amidotransferase-like domain-containing protein	NA	NA	NA	NA
WP_013282422.1|104089_104875_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_042258315.1|104864_105485_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_013282424.1|105474_105786_+	hypothetical protein	NA	NA	NA	NA
WP_013282425.1|105858_106173_+	hypothetical protein	NA	NA	NA	NA
WP_013282426.1|106187_106382_+	hypothetical protein	NA	NA	NA	NA
WP_013279565.1|106560_107031_+|transposase	IS200/IS605 family transposase	W0UUZ0	Sulfolobus_monocaudavirus	1.1e-18	35.5
WP_013282427.1|107215_108091_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013282428.1|108186_108534_+	NUDIX hydrolase	NA	NA	NA	NA
WP_013282429.1|108561_109179_+	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_013282430.1|109325_110381_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_013280040.1|110548_111667_+|transposase	IS110 family transposase	NA	NA	NA	NA