CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017341	Staphylococcus aureus subsp. aureus str. JKD6008, complete sequence	12 crisprs	cas3,DEDDh,DinG,csa3,WYL	7	1	12	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017341_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_1

419000-419100

Orphan

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_1

>merge|NC_017341|1|419000-419100|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NC_017341|1|1|419000-419100|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000211676.1\|410572_410782_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000052781.1\|414854_415424_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NC_017341.1\|WP_000793009.1\|422493_423762_+\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NC_017341.1\|WP_000991007.1\|416751_418140_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NC_017341.1\|WP_000868248.1\|411606_411990_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000956132.1\|419116_420073_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235334
NC_017341.1\|WP_000845143.1\|428817_429048_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378900
NC_017341.1\|WP_000930486.1\|413315_414839_-\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NC_017341.1\|WP_000746687.1\|412244_412871_-\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NC_017341.1\|WP_000264071.1\|423799_425266_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NC_017341.1\|WP_001289311.1\|415915_416671_+\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NC_017341.1\|WP_000421410.1\|421915_422494_+\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NC_017341.1\|WP_000237796.1\|426899_428093_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_017341.1\|WP_000633907.1\|428119_428320_-\|DUF3173-domain-containing-protein	unknown	unknown	gnl\|CDD\|371495
NC_017341.1\|WP_000466748.1\|410282_410534_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NC_017341.1\|WP_000424966.1\|425290_426832_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NC_017341.1\|WP_001789518.1\|418224_418326_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000394698.1\|420190_420853_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000763768.1\|420995_421403_-\|general-stress-protein	unknown	unknown	gnl\|CDD\|378584
NC_017341.1\|WP_000158374.1\|410959_411541_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000052781.1\|414854_415424_-\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NC_017341.1\|WP_000793009.1\|422493_423762_+\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.75897e-170
NC_017341.1\|WP_000991007.1\|416751_418140_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NC_017341.1\|WP_000956132.1\|419116_420073_-\|hypothetical-protein	gnl\|CDD\|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000748442
NC_017341.1\|WP_000845143.1\|428817_429048_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378900	pfam12645, HTH_16, Helix-turn-helix domain. This domain appears to be a helix-turn-helix domain suggesting that this might be a transcriptional regulatory protein. Some members of this family are annotated as conjugative transposon domains.	2.04673e-25
NC_017341.1\|WP_000930486.1\|413315_414839_-\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NC_017341.1\|WP_000746687.1\|412244_412871_-\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.67126e-71
NC_017341.1\|WP_000264071.1\|423799_425266_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NC_017341.1\|WP_001289311.1\|415915_416671_+\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
NC_017341.1\|WP_000421410.1\|421915_422494_+\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
NC_017341.1\|WP_000237796.1\|426899_428093_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.18096e-47
NC_017341.1\|WP_000633907.1\|428119_428320_-\|DUF3173-domain-containing-protein	gnl\|CDD\|371495	pfam11372, DUF3173, Domain of unknown function (DUF3173). This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualisation confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).	2.02242e-22
NC_017341.1\|WP_000466748.1\|410282_410534_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
NC_017341.1\|WP_000424966.1\|425290_426832_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_017341.1\|WP_000763768.1\|420995_421403_-\|general-stress-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.0219e-12
NC_017341.1\|WP_000158374.1\|410959_411541_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.78414e-49

>NC_017341.1|WP_001789518.1|418224_418326_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNSVVIGGKGK
>NC_017341.1|WP_000991007.1|416751_418140_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLIYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFDSNDNAALTSH
>NC_017341.1|WP_001289311.1|415915_416671_+|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NC_017341.1|WP_000052781.1|414854_415424_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NC_017341.1|WP_000930486.1|413315_414839_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NC_017341.1|WP_000746687.1|412244_412871_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASTLILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NC_017341.1|WP_000868248.1|411606_411990_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVEKNDSP
>NC_017341.1|WP_000158374.1|410959_411541_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSRAEAVDLKVENCKPYIIE
>NC_017341.1|WP_000211676.1|410572_410782_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFNPILSTFSNIIIHIDHFHANKKDDN
>NC_017341.1|WP_000466748.1|410282_410534_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK
>NC_017341.1|WP_000956132.1|419116_420073_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKALAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NC_017341.1|WP_000394698.1|420190_420853_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NC_017341.1|WP_000763768.1|420995_421403_-|general-stress-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHQEVHENNSAYEEIDITHFAEASKGPKA
>NC_017341.1|WP_000421410.1|421915_422494_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NC_017341.1|WP_000793009.1|422493_423762_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NC_017341.1|WP_000264071.1|423799_425266_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NC_017341.1|WP_000424966.1|425290_426832_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NC_017341.1|WP_000237796.1|426899_428093_-|site-specific-integrase
MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFNTKKEAREEYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFDKMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGNVKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDIDFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQTDFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDRLGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKEMKKVQ
>NC_017341.1|WP_000633907.1|428119_428320_-|DUF3173-domain-containing-protein
MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLDRVPREAVEEILGIRFSNENRSE
>NC_017341.1|WP_000845143.1|428817_429048_-|helix-turn-helix-domain-containing-protein
MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMTDEYGNSHMVIDETLRGRMETKLISKILSFEIK

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Crispr_ID: NC_017341_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_2

686715-686807

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_2

>merge|NC_017341|2|686715-686807|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTAAGGCACAACTGCATAAAAGCCTCTAATCGCTAAAGATGAAGAGGAACGCAGTTGGATGCTA

>NC_017341|2|2|686715-686807|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	AGGCACAACTGCATAAAAGCCTCTAATCG
CTAAAGATGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000477504.1\|679254_679731_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_017341.1\|WP_000362972.1\|689618_690419_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_017341.1\|WP_000655099.1\|683198_683306_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000735558.1\|690554_691061_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_001222133.1\|691222_691939_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_001021145.1\|683811_685473_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NC_017341.1\|WP_000359086.1\|683398_683815_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
NC_017341.1\|WP_000169042.1\|695592_695817_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NC_017341.1\|WP_000808902.1\|677400_678339_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NC_017341.1\|WP_000365354.1\|688915_689635_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NC_017341.1\|WP_000180230.1\|679770_681066_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NC_017341.1\|WP_001200748.1\|682113_683124_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NC_017341.1\|WP_001790232.1\|687910_688861_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NC_017341.1\|WP_014532846.1\|681093_681615_+\|YwhD-family-protein	unknown	unknown	gnl\|CDD\|378039
NC_017341.1\|WP_000901764.1\|685861_686497_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NC_017341.1\|WP_001045421.1\|692107_692896_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_017341.1\|WP_000749059.1\|686875_687763_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NC_017341.1\|WP_000633782.1\|678549_679086_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NC_017341.1\|WP_001553862.1\|694468_695398_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NC_017341.1\|WP_001018677.1\|693146_693521_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000477504.1\|679254_679731_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NC_017341.1\|WP_000362972.1\|689618_690419_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.35732e-24
NC_017341.1\|WP_000633782.1\|678549_679086_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NC_017341.1\|WP_001553862.1\|694468_695398_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	7.93315e-37
NC_017341.1\|WP_001021145.1\|683811_685473_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NC_017341.1\|WP_000359086.1\|683398_683815_+\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	2.62525e-58
NC_017341.1\|WP_000169042.1\|695592_695817_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
NC_017341.1\|WP_000808902.1\|677400_678339_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NC_017341.1\|WP_000365354.1\|688915_689635_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NC_017341.1\|WP_000180230.1\|679770_681066_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NC_017341.1\|WP_001200748.1\|682113_683124_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NC_017341.1\|WP_001790232.1\|687910_688861_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NC_017341.1\|WP_014532846.1\|681093_681615_+\|YwhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	1.21563e-97
NC_017341.1\|WP_000901764.1\|685861_686497_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NC_017341.1\|WP_001045421.1\|692107_692896_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.55978e-34
NC_017341.1\|WP_000749059.1\|686875_687763_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	8.54601e-73
NC_017341.1\|WP_001018677.1\|693146_693521_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26

>NC_017341.1|WP_000901764.1|685861_686497_+|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NC_017341.1|WP_001021145.1|683811_685473_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NC_017341.1|WP_000359086.1|683398_683815_+|DUF1934-domain-containing-protein
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NC_017341.1|WP_000655099.1|683198_683306_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NC_017341.1|WP_001200748.1|682113_683124_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NC_017341.1|WP_014532846.1|681093_681615_+|YwhD-family-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARARVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NC_017341.1|WP_000180230.1|679770_681066_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NC_017341.1|WP_000477504.1|679254_679731_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NC_017341.1|WP_000633782.1|678549_679086_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NC_017341.1|WP_000808902.1|677400_678339_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>NC_017341.1|WP_000749059.1|686875_687763_+|ABC-transporter-substrate-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NC_017341.1|WP_001790232.1|687910_688861_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NC_017341.1|WP_000365354.1|688915_689635_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NC_017341.1|WP_000362972.1|689618_690419_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMSGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NC_017341.1|WP_000735558.1|690554_691061_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NC_017341.1|WP_001222133.1|691222_691939_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NC_017341.1|WP_001045421.1|692107_692896_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLKFLKSVS
>NC_017341.1|WP_001018677.1|693146_693521_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NC_017341.1|WP_001553862.1|694468_695398_-|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NC_017341.1|WP_000169042.1|695592_695817_-|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

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Crispr_ID: NC_017341_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_3

802460-802542

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_3

>merge|NC_017341|3|802460-802542|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>NC_017341|3|3|802460-802542|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000022323.1\|790048_791053_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NC_017341.1\|WP_001790641.1\|803998_804100_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000876318.1\|812515_813487_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NC_017341.1\|WP_000525109.1\|793737_795621_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_017341.1\|WP_000098285.1\|791526_793467_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NC_017341.1\|WP_001790169.1\|789060_789267_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000663030.1\|800359_801418_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NC_017341.1\|WP_000708692.1\|789354_790065_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NC_017341.1\|WP_000429014.1\|802990_803908_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NC_017341.1\|WP_000983677.1\|795632_797414_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NC_017341.1\|WP_000589260.1\|797635_798613_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NC_017341.1\|WP_000855505.1\|808571_810677_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NC_017341.1\|WP_000930014.1\|806023_806524_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NC_017341.1\|WP_000193751.1\|804177_805683_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NC_017341.1\|WP_001068497.1\|806543_807410_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_017341.1\|WP_000180991.1\|798605_800120_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NC_017341.1\|WP_000562498.1\|810794_811766_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NC_017341.1\|WP_000197271.1\|801768_802311_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NC_017341.1\|WP_000692521.1\|808210_808609_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NC_017341.1\|WP_000499195.1\|812321_812477_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000022323.1\|790048_791053_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
NC_017341.1\|WP_000876318.1\|812515_813487_+\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
NC_017341.1\|WP_000525109.1\|793737_795621_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_017341.1\|WP_000098285.1\|791526_793467_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NC_017341.1\|WP_000562498.1\|810794_811766_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NC_017341.1\|WP_000663030.1\|800359_801418_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NC_017341.1\|WP_000708692.1\|789354_790065_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.29969e-94
NC_017341.1\|WP_000429014.1\|802990_803908_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	3.10512e-78
NC_017341.1\|WP_000193751.1\|804177_805683_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NC_017341.1\|WP_000589260.1\|797635_798613_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.80291e-155
NC_017341.1\|WP_000855505.1\|808571_810677_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NC_017341.1\|WP_000930014.1\|806023_806524_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
NC_017341.1\|WP_000983677.1\|795632_797414_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_017341.1\|WP_001068497.1\|806543_807410_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.8323e-10
NC_017341.1\|WP_000180991.1\|798605_800120_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
NC_017341.1\|WP_000197271.1\|801768_802311_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	1.15481e-107
NC_017341.1\|WP_000692521.1\|808210_808609_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56

>NC_017341.1|WP_000197271.1|801768_802311_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPYAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NC_017341.1|WP_000663030.1|800359_801418_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NC_017341.1|WP_000180991.1|798605_800120_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NC_017341.1|WP_000589260.1|797635_798613_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQLLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NC_017341.1|WP_000983677.1|795632_797414_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NC_017341.1|WP_000525109.1|793737_795621_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMMDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREENEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NC_017341.1|WP_000098285.1|791526_793467_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NC_017341.1|WP_000022323.1|790048_791053_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NC_017341.1|WP_000708692.1|789354_790065_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NC_017341.1|WP_001790169.1|789060_789267_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NC_017341.1|WP_000429014.1|802990_803908_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMTHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NC_017341.1|WP_001790641.1|803998_804100_+|hypothetical-protein
MVINEIDFYRVGRENIVIAVYNEHIKFLFILIS
>NC_017341.1|WP_000193751.1|804177_805683_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NC_017341.1|WP_000930014.1|806023_806524_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NC_017341.1|WP_001068497.1|806543_807410_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NC_017341.1|WP_000692521.1|808210_808609_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NC_017341.1|WP_000855505.1|808571_810677_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NC_017341.1|WP_000562498.1|810794_811766_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NC_017341.1|WP_000499195.1|812321_812477_+|hypothetical-protein
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NC_017341.1|WP_000876318.1|812515_813487_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

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Crispr_ID: NC_017341_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_4

850339-850424

Unclear

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_4

>merge|NC_017341|4|850339-850424|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NC_017341|4|4|850339-850424|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000816295.1\|855158_856061_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NC_017341.1\|WP_001224793.1\|847042_847528_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NC_017341.1\|WP_000958224.1\|845257_846190_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NC_017341.1\|WP_000749380.1\|837591_838431_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NC_017341.1\|WP_001074753.1\|860250_861441_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NC_017341.1\|WP_000006551.1\|852811_853756_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NC_017341.1\|WP_000134963.1\|849041_849977_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NC_017341.1\|WP_001260089.1\|861562_862324_+\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NC_017341.1\|WP_000513308.1\|846195_847035_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NC_017341.1\|WP_000638419.1\|839251_839488_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NC_017341.1\|WP_000279414.1\|859101_860112_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NC_017341.1\|WP_000369727.1\|850798_851710_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NC_017341.1\|WP_000229253.1\|839756_841742_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NC_017341.1\|WP_001049165.1\|854328_854916_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NC_017341.1\|WP_000538141.1\|838604_839255_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NC_017341.1\|WP_000070826.1\|856763_857393_+\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NC_017341.1\|WP_000057549.1\|847535_848975_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NC_017341.1\|WP_001248939.1\|851706_852702_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NC_017341.1\|WP_000662681.1\|841749_844596_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NC_017341.1\|WP_000654030.1\|858035_859049_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000816295.1\|855158_856061_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	4.94096e-153
NC_017341.1\|WP_001224793.1\|847042_847528_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NC_017341.1\|WP_000958224.1\|845257_846190_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NC_017341.1\|WP_000749380.1\|837591_838431_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	2.23913e-42
NC_017341.1\|WP_001074753.1\|860250_861441_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NC_017341.1\|WP_000006551.1\|852811_853756_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NC_017341.1\|WP_000134963.1\|849041_849977_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NC_017341.1\|WP_001260089.1\|861562_862324_+\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.84083e-146
NC_017341.1\|WP_000513308.1\|846195_847035_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.39921e-119
NC_017341.1\|WP_000638419.1\|839251_839488_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NC_017341.1\|WP_000279414.1\|859101_860112_+\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NC_017341.1\|WP_000369727.1\|850798_851710_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	7.64647e-169
NC_017341.1\|WP_000229253.1\|839756_841742_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NC_017341.1\|WP_001049165.1\|854328_854916_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NC_017341.1\|WP_000538141.1\|838604_839255_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NC_017341.1\|WP_000070826.1\|856763_857393_+\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.85535e-05
NC_017341.1\|WP_000057549.1\|847535_848975_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.31987e-06
NC_017341.1\|WP_001248939.1\|851706_852702_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NC_017341.1\|WP_000662681.1\|841749_844596_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_017341.1\|WP_000654030.1\|858035_859049_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92

>NC_017341.1|WP_000134963.1|849041_849977_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NC_017341.1|WP_000057549.1|847535_848975_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDMEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLSDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NC_017341.1|WP_001224793.1|847042_847528_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NC_017341.1|WP_000513308.1|846195_847035_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NC_017341.1|WP_000958224.1|845257_846190_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NC_017341.1|WP_000662681.1|841749_844596_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NC_017341.1|WP_000229253.1|839756_841742_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NC_017341.1|WP_000638419.1|839251_839488_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NC_017341.1|WP_000538141.1|838604_839255_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NC_017341.1|WP_000749380.1|837591_838431_+|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVTKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NC_017341.1|WP_000369727.1|850798_851710_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKGTRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NC_017341.1|WP_001248939.1|851706_852702_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NC_017341.1|WP_000006551.1|852811_853756_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NC_017341.1|WP_001049165.1|854328_854916_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NC_017341.1|WP_000816295.1|855158_856061_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKALFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NC_017341.1|WP_000070826.1|856763_857393_+|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NC_017341.1|WP_000654030.1|858035_859049_+|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NC_017341.1|WP_000279414.1|859101_860112_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NC_017341.1|WP_001074753.1|860250_861441_+|phosphoglycerate-kinase
MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMVYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NC_017341.1|WP_001260089.1|861562_862324_+|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK

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Crispr_ID: NC_017341_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_5

900179-900260

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_5

>merge|NC_017341|5|900179-900260|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NC_017341|5|5|900179-900260|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_001033317.1\|906497_907226_-\|staphylococcal-enterotoxin-type-Q	unknown	unknown	gnl\|CDD\|280949
NC_017341.1\|WP_181875734.1\|898437_898497_-\|erythromycin-resistance-leader-peptide	unknown	unknown	gnl\|CDD\|285460
NC_017341.1\|WP_000732326.1\|903472_904294_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NC_017341.1\|WP_000264182.1\|904437_905658_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_017341.1\|WP_000067268.1\|896740_897523_+\|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia	unknown	unknown	gnl\|CDD\|184296
NC_017341.1\|WP_001092058.1\|898888_899551_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225136
NC_017341.1\|WP_000361059.1\|896212_896590_+\|transposase	unknown	unknown	unknown
NC_017341.1\|WP_000868132.1\|893231_894317_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271186
NC_017341.1\|WP_001065801.1\|901195_901492_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NC_017341.1\|WP_001190695.1\|890972_891293_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NC_017341.1\|WP_000290486.1\|891950_892331_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NC_017341.1\|WP_000571218.1\|901741_902767_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NC_017341.1\|WP_001018962.1\|900816_901203_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NC_017341.1\|WP_001072197.1\|897648_898380_-\|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)	unknown	unknown	gnl\|CDD\|366074
NC_017341.1\|WP_001557544.1\|894313_896206_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271187
NC_017341.1\|WP_000142630.1\|907400_908135_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_017341.1\|WP_000520233.1\|902759_903455_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NC_017341.1\|WP_000733773.1\|905745_906474_-\|staphylococcal-enterotoxin-type-K	unknown	unknown	gnl\|CDD\|280949
NC_017341.1\|WP_001063624.1\|908284_908497_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NC_017341.1\|WP_000589549.1\|891436_891793_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_181875734.1\|898437_898497_-\|erythromycin-resistance-leader-peptide	gnl\|CDD\|285460	pfam08253, Leader_Erm, Erm Leader peptide. These short proteins are Leader peptides (15-19 amino acids) of erm genes that code for resistance determinants in Staphylococcus aureus.	0.00566709
NC_017341.1\|WP_000732326.1\|903472_904294_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NC_017341.1\|WP_000264182.1\|904437_905658_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.81902e-37
NC_017341.1\|WP_000067268.1\|896740_897523_+\|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia	gnl\|CDD\|184296	PRK13746, PRK13746, aminoglycoside resistance protein; Provisional.	2.99486e-84
NC_017341.1\|WP_001092058.1\|898888_899551_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	5.63343e-23
NC_017341.1\|WP_001033317.1\|906497_907226_-\|staphylococcal-enterotoxin-type-Q	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	7.79999e-28
NC_017341.1\|WP_000868132.1\|893231_894317_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271186	cd01186, INT_tnpA_C_Tn554, Putative Transposase A from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase A from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	4.0175e-100
NC_017341.1\|WP_001065801.1\|901195_901492_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NC_017341.1\|WP_001190695.1\|890972_891293_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NC_017341.1\|WP_000290486.1\|891950_892331_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	5.19502e-68
NC_017341.1\|WP_000571218.1\|901741_902767_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NC_017341.1\|WP_001018962.1\|900816_901203_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NC_017341.1\|WP_001072197.1\|897648_898380_-\|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)	gnl\|CDD\|366074	pfam00398, RrnaAD, Ribosomal RNA adenine dimethylase.	3.53992e-85
NC_017341.1\|WP_001557544.1\|894313_896206_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271187	cd01187, INT_tnpB_C_Tn554, Putative Transposase B from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase B from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	6.6262e-52
NC_017341.1\|WP_000142630.1\|907400_908135_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.1934e-12
NC_017341.1\|WP_000520233.1\|902759_903455_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NC_017341.1\|WP_000733773.1\|905745_906474_-\|staphylococcal-enterotoxin-type-K	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	3.87599e-25
NC_017341.1\|WP_001063624.1\|908284_908497_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	7.52525e-13
NC_017341.1\|WP_000589549.1\|891436_891793_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56

>NC_017341.1|WP_001092058.1|898888_899551_+|methyltransferase-domain-containing-protein
MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGCGSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIVSRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCFKFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVWTK
>NC_017341.1|WP_181875734.1|898437_898497_-|erythromycin-resistance-leader-peptide
MGTFSIFVINKVSYQPNQN
>NC_017341.1|WP_001072197.1|897648_898380_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)
MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHFTKELVKMSRSVIAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPPLYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYKLFH
>NC_017341.1|WP_000067268.1|896740_897523_+|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia
MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRINSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYPPKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLTDIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEHVTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN
>NC_017341.1|WP_000361059.1|896212_896590_+|transposase
MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNSIAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVMELEKENKKLQNQIQKLYGDLYNKE
>NC_017341.1|WP_001557544.1|894313_896206_+|tyrosine-type-recombinase/integrase
MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPSAIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKMLDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSYYVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYFKQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSELNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEFVLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKMKKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQNIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETLKNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGCPHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQIIGSLTG
>NC_017341.1|WP_000868132.1|893231_894317_+|tyrosine-type-recombinase/integrase
MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPNTIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREETTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRVKKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIHLTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFGKPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTTLNTYVHLSDQDMKNEFNKYLERKEHKK
>NC_017341.1|WP_000290486.1|891950_892331_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVGISDESQIEALLTAEKYSEMIGE
>NC_017341.1|WP_000589549.1|891436_891793_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NC_017341.1|WP_001190695.1|890972_891293_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NC_017341.1|WP_001018962.1|900816_901203_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NC_017341.1|WP_001065801.1|901195_901492_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NC_017341.1|WP_000571218.1|901741_902767_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NC_017341.1|WP_000520233.1|902759_903455_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NC_017341.1|WP_000732326.1|903472_904294_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NC_017341.1|WP_000264182.1|904437_905658_-|site-specific-integrase
MWFEKFKNKNKETKYRYYEKYKDPLTNKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHAASDEWFQNYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDSKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINMKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG
>NC_017341.1|WP_000733773.1|905745_906474_-|staphylococcal-enterotoxin-type-K
MKKLISILLINIIILGVSNNASAQGDIGIDNLRNFYTKKDFVDLKDVKDNDTPIANQLQFSNESYDLISESKDFNKFSNFKGKKLDVFGISYNGQCNTKYIYGGVTATNEYLDKSRNIPINIWINGNHKTISTNKVSTNKKLVTAQEIDVKLRKYLQEEYNIYGHNGTKKGEEYGHKSKFYSGFNIGKVTFHLNNNDTFSYDLFYTGDDGLPKSFLKIYEDNKTVESEKFHLDVDISYKETI
>NC_017341.1|WP_001033317.1|906497_907226_-|staphylococcal-enterotoxin-type-Q
MNKIFRILTVSLFFFTFLIKNNLAYADVGVINLRNFYANYEPEKLQGVSSGNFSTSHQLEYIDGKYTLYSQFHNEYEAKRLKDHKVDIFGISYSGLCNTKYMYGGITLANQNLDKPRNIPINLWVNGKQNTISTDKVSTQKKEVTAQEIDIKLRKYLQNEYNIYGFNKTKKGQEYGYQSKFNSGFNKGKITFHLNNEPSFTYDLFYTGTGQAESFLKIYNDNKTIDAENFHLDVEISYEKTE
>NC_017341.1|WP_000142630.1|907400_908135_-|helix-turn-helix-transcriptional-regulator
MTFGEILKKERVSWKLSVKELSTLSGVSQTYISKLENGKRNFPSLETIFNLLIGFKTHIEYKMGSESPFYEINNSYLDEILIMFINSSNSTISDRDPNELITQFNEYYDVTIKKKQNENSKIESDIFSNKIKLVKGTTKKEVIEKPYFDLNWLLTQNEYEVFFDRSFLLDNNFLNKKHFTEKDMYYYNVLNDNDLKTIKDLIVVFLLNKYNYIKNKDDFFNIFTNSEDDKTKRDALYKILYETD
>NC_017341.1|WP_001063624.1|908284_908497_+|helix-turn-helix-transcriptional-regulator
MNNNLSLLMGKHRVTASKLSTVTGISRTSIHGLYHERTENPDTKTVMKLCEYFNITPNEFFGIIEKEGVK

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Crispr_ID: NC_017341_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_6

1100626-1100713

Orphan

Consensus_repeat	Method
CCCCTAACAACTAAAAGTTGTAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_6

>merge|NC_017341|6|1100626-1100713|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGGAAGGAGAGGGATACATGCGCCGAGCACATGCATAAAATCCCCTAACAACTAAAAGTTGTAAGG

>NC_017341|6|6|1100626-1100713|CRISPRCasFinder
CCCCTAACAACTAAAAGTTGTAAGG	AAGGAGAGGGATACATGCGCCGAGCACATGCATAAAAT
CCCCTAACAACTAAAAGTTGTAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000238664.1\|1093756_1094323_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|223376
NC_017341.1\|WP_000685079.1\|1102728_1103901_+\|class-I-SAM-dependent-rRNA-methyltransferase	unknown	unknown	gnl\|CDD\|224017
NC_017341.1\|WP_000921968.1\|1098148_1099549_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213192
NC_017341.1\|WP_001289614.1\|1106874_1107108_-\|glutaredoxin-like-protein-NrdH	unknown	unknown	gnl\|CDD\|239274
NC_017341.1\|WP_000505965.1\|1103954_1104497_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368297
NC_017341.1\|WP_000483713.1\|1091248_1092733_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NC_017341.1\|WP_000638456.1\|1108663_1109683_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NC_017341.1\|WP_000381849.1\|1107305_1108667_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587
NC_017341.1\|WP_001101908.1\|1095837_1097085_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|237507
NC_017341.1\|WP_000273253.1\|1097349_1098156_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NC_017341.1\|WP_000666799.1\|1088416_1089088_+\|phosphoribosylformylglycinamidine-synthase-I	unknown	unknown	gnl\|CDD\|235140
NC_017341.1\|WP_000437472.1\|1104650_1104917_+\|phosphocarrier-protein-HPr	unknown	unknown	gnl\|CDD\|237503
NC_017341.1\|WP_000514290.1\|1109815_1110478_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NC_017341.1\|WP_000064214.1\|1100722_1100857_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000033477.1\|1099563_1100139_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|227065
NC_017341.1\|WP_000040054.1\|1104919_1106638_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NC_017341.1\|WP_000009069.1\|1101008_1102304_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000030812.1\|1092725_1093754_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NC_017341.1\|WP_000032727.1\|1089080_1091270_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl\|CDD\|234921
NC_017341.1\|WP_000709290.1\|1094337_1095816_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000238664.1\|1093756_1094323_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|223376	COG0299, PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism].	7.23817e-92
NC_017341.1\|WP_000273253.1\|1097349_1098156_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	7.39205e-29
NC_017341.1\|WP_001289614.1\|1106874_1107108_-\|glutaredoxin-like-protein-NrdH	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	5.00495e-16
NC_017341.1\|WP_000505965.1\|1103954_1104497_+\|hypothetical-protein	gnl\|CDD\|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	0.00779365
NC_017341.1\|WP_000483713.1\|1091248_1092733_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NC_017341.1\|WP_000638456.1\|1108663_1109683_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	6.42118e-76
NC_017341.1\|WP_000381849.1\|1107305_1108667_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	2.48829e-165
NC_017341.1\|WP_001101908.1\|1095837_1097085_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|237507	PRK13790, PRK13790, phosphoribosylamine--glycine ligase; Provisional.	0
NC_017341.1\|WP_000685079.1\|1102728_1103901_+\|class-I-SAM-dependent-rRNA-methyltransferase	gnl\|CDD\|224017	COG1092, COG1092, Predicted SAM-dependent methyltransferases [General function prediction only].	5.6543e-145
NC_017341.1\|WP_000666799.1\|1088416_1089088_+\|phosphoribosylformylglycinamidine-synthase-I	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	1.77638e-140
NC_017341.1\|WP_000437472.1\|1104650_1104917_+\|phosphocarrier-protein-HPr	gnl\|CDD\|237503	PRK13780, PRK13780, phosphocarrier protein HPr; Provisional.	2.44795e-51
NC_017341.1\|WP_000921968.1\|1098148_1099549_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.67975e-64
NC_017341.1\|WP_000514290.1\|1109815_1110478_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	4.35421e-66
NC_017341.1\|WP_000033477.1\|1099563_1100139_-\|ECF-transporter-S-component	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	4.34592e-70
NC_017341.1\|WP_000040054.1\|1104919_1106638_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NC_017341.1\|WP_000030812.1\|1092725_1093754_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NC_017341.1\|WP_000032727.1\|1089080_1091270_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl\|CDD\|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
NC_017341.1\|WP_000709290.1\|1094337_1095816_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0

>NC_017341.1|WP_000033477.1|1099563_1100139_-|ECF-transporter-S-component
MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQLTNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELVFAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVAGVLSYLLVKALDKTGVTKLFRPAAKEDYDNL
>NC_017341.1|WP_000921968.1|1098148_1099549_-|ABC-transporter-ATP-binding-protein
MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKSTLLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQLPREDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAMLDVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQKYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGLGEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQFITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLQNVKDQHPYELSIGQKRRLSVATALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRLKISDGALLDCDGDTNV
>NC_017341.1|WP_000273253.1|1097349_1098156_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYITILMLVFLLMFNGTQFKITAIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTESLVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLMISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRDGPRTYYYNVPFSYKDIIFIIVLIAIITMAYYCSITLPITGIDDVRLGRVG
>NC_017341.1|WP_001101908.1|1095837_1097085_+|phosphoribosylamine--glycine-ligase
MNVLVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYKKVSQIQSDHLFYRHDIANKALQLK
>NC_017341.1|WP_000709290.1|1094337_1095816_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVPVRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLYPFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYQEVLTRLRNDSLDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIAGAKQLHGKQLSYNNIKDADATLALVKKFDTPATVAVKHMNPCGVGIGDTIEQAFQHAYEADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEIDMTIDSNEEEFVSVSGGYLVQDKDNYVVPKEEMKVVTEVAPTDEQWEAMLLGWKVVPSVKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVELAAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH
>NC_017341.1|WP_000238664.1|1093756_1094323_+|phosphoribosylglycinamide-formyltransferase
MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPKQFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRPDDSKEQLEEKVKKLEYELYPSVIAKIVK
>NC_017341.1|WP_000030812.1|1092725_1093754_+|phosphoribosylformylglycinamidine-cyclo-ligase
MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDVSRALKILAEQNVEAYQIGHIVKNESTAIELLGV
>NC_017341.1|WP_000483713.1|1091248_1092733_+|amidophosphoribosyltransferase
MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
>NC_017341.1|WP_000032727.1|1089080_1091270_+|phosphoribosylformylglycinamidine-synthase-subunit-PurL
MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
>NC_017341.1|WP_000666799.1|1088416_1089088_+|phosphoribosylformylglycinamidine-synthase-I
MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGVLIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALLHNDSHLFISRNEELEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANNQIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSWREQHV
>NC_017341.1|WP_000064214.1|1100722_1100857_-|hypothetical-protein
MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
>NC_017341.1|WP_000009069.1|1101008_1102304_+|hypothetical-protein
MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVDTHVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDYDISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHFMWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRRALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAKRDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFVSGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLTEFINIMIHGLLLSVFITPTLLLMLLAIIISYSLQLRERP
>NC_017341.1|WP_000685079.1|1102728_1103901_+|class-I-SAM-dependent-rRNA-methyltransferase
MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDKSQYVATAYVGRQHKGLGWVLTYDKAQQINTAFFVKLFNTALAERDYYFNIDGTNAFRLFNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDSEYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHVLNLFSYTGAFSAIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDFYKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLINGALNILSSEGTLLLCTNASVYPLKQFKNTIKKTLEESGVDYELTEVMGLPKDFKTHPHYKPSKYLKAVFVNIRH
>NC_017341.1|WP_000505965.1|1103954_1104497_+|hypothetical-protein
MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRQRAEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVKERIMSAAAIQGSQFIGKRISNAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYFMNKIGKDHIQKCENVIKNVM
>NC_017341.1|WP_000437472.1|1104650_1104917_+|phosphocarrier-protein-HPr
MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
>NC_017341.1|WP_000040054.1|1104919_1106638_+|phosphoenolpyruvate--protein-phosphotransferase
MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMGGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK
>NC_017341.1|WP_001289614.1|1106874_1107108_-|glutaredoxin-like-protein-NrdH
MSEIIVYTQNDCPPCTFVKNYLNEHHIDFEERNINNQQYRNEMIDFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD
>NC_017341.1|WP_000381849.1|1107305_1108667_+|cytochrome-ubiquinol-oxidase-subunit-I
MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKNDLQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAFFFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKNGKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKKALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDEKTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCFVISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGYMRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGEIEK
>NC_017341.1|WP_000638456.1|1108663_1109683_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKINHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSFYAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLSPFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFLSLRIQNSEHFYSAVFDYWWMFGISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFGYGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYVEGKKS
>NC_017341.1|WP_000514290.1|1109815_1110478_+|TrkA-family-potassium-uptake-protein
MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDIATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQNDYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAGQSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIATR

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Crispr_ID: NC_017341_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_7

1184915-1185000

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_7

>merge|NC_017341|7|1184915-1185000|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>NC_017341|7|7|1184915-1185000|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000739522.1\|1186819_1187545_-\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NC_017341.1\|WP_000398672.1\|1194802_1194937_+\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NC_017341.1\|WP_001239288.1\|1192506_1193454_-\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NC_017341.1\|WP_001074345.1\|1189006_1189939_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NC_017341.1\|WP_000149423.1\|1191974_1192202_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000739563.1\|1177763_1178165_-\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NC_017341.1\|WP_000584398.1\|1178836_1179343_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000791587.1\|1179601_1180099_+\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NC_017341.1\|WP_001063559.1\|1185999_1186725_-\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NC_017341.1\|WP_001791789.1\|1177711_1177804_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000848124.1\|1182715_1183675_-\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
NC_017341.1\|WP_000669537.1\|1180252_1180603_+\|complement-inhibitor-SCIN-B	unknown	unknown	gnl\|CDD\|371594
NC_017341.1\|WP_000432079.1\|1190110_1191667_+\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NC_017341.1\|WP_000231632.1\|1182005_1182239_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000765708.1\|1184347_1184494_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_001245802.1\|1193702_1193891_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NC_017341.1\|WP_000041896.1\|1185175_1185892_-\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NC_017341.1\|WP_001032814.1\|1181198_1181384_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_001802045.1\|1184450_1184675_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000793605.1\|1187982_1188984_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000739522.1\|1186819_1187545_-\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	4.88527e-160
NC_017341.1\|WP_000398672.1\|1194802_1194937_+\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NC_017341.1\|WP_001074345.1\|1189006_1189939_+\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NC_017341.1\|WP_000791587.1\|1179601_1180099_+\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.40265e-27
NC_017341.1\|WP_000739563.1\|1177763_1178165_-\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	3.87075e-77
NC_017341.1\|WP_001239288.1\|1192506_1193454_-\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	1.39126e-83
NC_017341.1\|WP_001063559.1\|1185999_1186725_-\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NC_017341.1\|WP_000848124.1\|1182715_1183675_-\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.62736e-140
NC_017341.1\|WP_000669537.1\|1180252_1180603_+\|complement-inhibitor-SCIN-B	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
NC_017341.1\|WP_000432079.1\|1190110_1191667_+\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NC_017341.1\|WP_000041896.1\|1185175_1185892_-\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
NC_017341.1\|WP_001245802.1\|1193702_1193891_+\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NC_017341.1\|WP_000793605.1\|1187982_1188984_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0

>NC_017341.1|WP_001802045.1|1184450_1184675_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NC_017341.1|WP_000765708.1|1184347_1184494_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NC_017341.1|WP_000848124.1|1182715_1183675_-|alpha-hemolysin
MKTHIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWIDRSSERYKIDWEKEEMTN
>NC_017341.1|WP_000231632.1|1182005_1182239_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NC_017341.1|WP_001032814.1|1181198_1181384_-|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NC_017341.1|WP_000669537.1|1180252_1180603_+|complement-inhibitor-SCIN-B
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>NC_017341.1|WP_000791587.1|1179601_1180099_+|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTLAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>NC_017341.1|WP_000584398.1|1178836_1179343_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NC_017341.1|WP_000739563.1|1177763_1178165_-|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
>NC_017341.1|WP_001791789.1|1177711_1177804_-|hypothetical-protein
MLKTVKSTRLLGIKKHTELNSCTPNVRKQC
>NC_017341.1|WP_000041896.1|1185175_1185892_-|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NC_017341.1|WP_001063559.1|1185999_1186725_-|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NC_017341.1|WP_000739522.1|1186819_1187545_-|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYNQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NC_017341.1|WP_000793605.1|1187982_1188984_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NC_017341.1|WP_001074345.1|1189006_1189939_+|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIGENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NC_017341.1|WP_000432079.1|1190110_1191667_+|YfcC-family-protein
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSVAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NC_017341.1|WP_000149423.1|1191974_1192202_+|hypothetical-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NC_017341.1|WP_001239288.1|1192506_1193454_-|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLKNVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NC_017341.1|WP_001245802.1|1193702_1193891_+|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NC_017341.1|WP_000398672.1|1194802_1194937_+|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF

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Crispr_ID: NC_017341_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_8

1954012-1954139

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_8

>merge|NC_017341|8|1954012-1954139|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>NC_017341|8|8|1954012-1954139|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_001791878.1\|1967017_1967110_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_001251224.1\|1945945_1946545_-\|glucosamine-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|223440
NC_017341.1\|WP_000379098.1\|1971178_1972156_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NC_017341.1\|WP_000031108.1\|1945768_1945921_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_001011598.1\|1964251_1965541_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493
NC_017341.1\|WP_000251253.1\|1969145_1969688_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NC_017341.1\|WP_000284752.1\|1969989_1971027_-\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NC_017341.1\|WP_000869455.1\|1962759_1963710_-\|phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
NC_017341.1\|WP_000901021.1\|1944596_1944992_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000597238.1\|1967118_1968855_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	unknown	unknown	gnl\|CDD\|224055
NC_017341.1\|WP_000649907.1\|1949171_1950629_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NC_017341.1\|WP_000063582.1\|1950886_1951948_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NC_017341.1\|WP_000939521.1\|1963715_1964171_-\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|224146
NC_017341.1\|WP_001549130.1\|1952440_1953802_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NC_017341.1\|WP_001236371.1\|1965833_1966928_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NC_017341.1\|WP_000379978.1\|1947178_1948306_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	unknown	unknown	gnl\|CDD\|272993
NC_017341.1\|WP_000181398.1\|1946703_1947174_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|223297
NC_017341.1\|WP_000590809.1\|1948456_1949179_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_017341.1\|WP_000110013.1\|1962216_1962663_-\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NC_017341.1\|WP_031784974.1\|1953777_1953891_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_001251224.1\|1945945_1946545_-\|glucosamine-6-phosphate-isomerase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	1.49007e-10
NC_017341.1\|WP_000379098.1\|1971178_1972156_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	2.87563e-40
NC_017341.1\|WP_000590809.1\|1948456_1949179_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.70748e-153
NC_017341.1\|WP_001011598.1\|1964251_1965541_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
NC_017341.1\|WP_000251253.1\|1969145_1969688_-\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.12131e-126
NC_017341.1\|WP_000284752.1\|1969989_1971027_-\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	1.36048e-156
NC_017341.1\|WP_001236371.1\|1965833_1966928_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.5476e-86
NC_017341.1\|WP_000597238.1\|1967118_1968855_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_017341.1\|WP_000649907.1\|1949171_1950629_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.14709e-98
NC_017341.1\|WP_000869455.1\|1962759_1963710_-\|phosphoglycerate-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.59103e-136
NC_017341.1\|WP_001549130.1\|1952440_1953802_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.46337e-114
NC_017341.1\|WP_000110013.1\|1962216_1962663_-\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	1.02665e-55
NC_017341.1\|WP_000379978.1\|1947178_1948306_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	1.37066e-179
NC_017341.1\|WP_000181398.1\|1946703_1947174_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.34563e-87
NC_017341.1\|WP_000063582.1\|1950886_1951948_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	2.31644e-122
NC_017341.1\|WP_000939521.1\|1963715_1964171_-\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.44283e-68

>NC_017341.1|WP_031784974.1|1953777_1953891_+|hypothetical-protein
MYFKNSSLNYIPTTFGGEPKETLFYKVSNTLCYVNNS
>NC_017341.1|WP_001549130.1|1952440_1953802_+|ISL3-family-transposase
MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPDYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRHSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKAVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKRRQPSPIMDWPPNNKNSKSCILKIVL
>NC_017341.1|WP_000063582.1|1950886_1951948_-|PTS-transporter-subunit-IIC
MSNANNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>NC_017341.1|WP_000649907.1|1949171_1950629_-|ABC-transporter-permease-subunit
MKCLIRFILVLGLLISSAMVYINPTAHAEQDQTWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLIVAAALYFVLTFVLTRIMNMIEGRLNASD
>NC_017341.1|WP_000590809.1|1948456_1949179_-|amino-acid-ABC-transporter-ATP-binding-protein
MIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>NC_017341.1|WP_000379978.1|1947178_1948306_-|tRNA-epoxyqueuosine(34)-reductase-QueG
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPLIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>NC_017341.1|WP_000181398.1|1946703_1947174_-|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEVTNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>NC_017341.1|WP_001251224.1|1945945_1946545_-|glucosamine-6-phosphate-isomerase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>NC_017341.1|WP_000031108.1|1945768_1945921_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>NC_017341.1|WP_000901021.1|1944596_1944992_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITAILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>NC_017341.1|WP_000110013.1|1962216_1962663_-|peroxide-responsive-transcriptional-repressor-PerR
MSVEIESIEHELEESVASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>NC_017341.1|WP_000869455.1|1962759_1963710_-|phosphoglycerate-dehydrogenase
MKVVGLNRMREVETELQQRFSDLDFKFYKKASEIPESDLADLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIIINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEALLIEVLKSKVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
>NC_017341.1|WP_000939521.1|1963715_1964171_-|thioredoxin-dependent-thiol-peroxidase
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG
>NC_017341.1|WP_001011598.1|1964251_1965541_+|glutamate-1-semialdehyde-2,1-aminomutase
MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
>NC_017341.1|WP_001236371.1|1965833_1966928_+|aromatic-acid-exporter-family-protein
MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL
>NC_017341.1|WP_001791878.1|1967017_1967110_-|hypothetical-protein
MFDFSTILKRKFVTGWWGHNIEKAVRDFLN
>NC_017341.1|WP_000597238.1|1967118_1968855_-|SAV1866-family-putative-multidrug-efflux-ABC-transporter
MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQNL
>NC_017341.1|WP_000251253.1|1969145_1969688_-|DUF402-domain-containing-protein
MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKERYKKIRQY
>NC_017341.1|WP_000284752.1|1969989_1971027_-|A/G-specific-adenine-glycosylase
MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVHDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFESEHARRKMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGAINIETLPDDMIWFDLSDRDQYTFPVPMSKIYQFING
>NC_017341.1|WP_000379098.1|1971178_1972156_+|metal-dependent-hydrolase
MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTNPFHVWMWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVIGLHPFAVFFPIIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDYVGKAYGRNVVFSDKVERQTLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTEIRLIDLRYLKNDHYSFVAIAHVTNDNVIDHSYIGWVFTEDKLQRKLYAK

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Crispr_ID: NC_017341_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_9

2295085-2295235

Orphan

Consensus_repeat	Method
AACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

2 spacers

csa3

The CRISPR arrays of NC_017341_9

>merge|NC_017341|9|2295085-2295235|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTAAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCTTTCTA

>NC_017341|9|9|2295085-2295235|CRISPRCasFinder
AACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTACTTTTA
AACTTTAGTTGTTAGGGGCTCTTATGCA	GTTGATGCGTAGCATCCAACTGTGTTCCTCTATTTTTC
AACTTTAGTTGTTAGGGGCTTCTTTCTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000003760.1\|2292407_2292728_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_017341.1\|WP_000495671.1\|2293975_2295067_+\|lytic-regulatory-protein	unknown	unknown	unknown
NC_017341.1\|WP_001292149.1\|2306721_2307156_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NC_017341.1\|WP_001024106.1\|2291590_2292256_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NC_017341.1\|WP_000808820.1\|2289956_2290187_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000123393.1\|2287911_2289285_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NC_017341.1\|WP_000648718.1\|2307155_2308262_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NC_017341.1\|WP_000370924.1\|2298579_2299437_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NC_017341.1\|WP_000115564.1\|2296357_2297494_-\|SAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|366887
NC_017341.1\|WP_000160304.1\|2285566_2286277_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NC_017341.1\|WP_001123303.1\|2287040_2287454_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NC_017341.1\|WP_001802298.1\|2295566_2295671_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000334465.1\|2300518_2302324_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_017341.1\|WP_001127960.1\|2290217_2291156_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NC_017341.1\|WP_001790138.1\|2297782_2297875_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000908176.1\|2299504_2300287_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NC_017341.1\|WP_000070866.1\|2286397_2286841_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NC_017341.1\|WP_000083807.1\|2303004_2304543_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NC_017341.1\|WP_000019744.1\|2292729_2293710_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NC_017341.1\|WP_000927363.1\|2304577_2306710_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000003760.1\|2292407_2292728_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	6.02572e-17
NC_017341.1\|WP_000648718.1\|2307155_2308262_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_017341.1\|WP_001292149.1\|2306721_2307156_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NC_017341.1\|WP_001024106.1\|2291590_2292256_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.24255e-48
NC_017341.1\|WP_000123393.1\|2287911_2289285_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NC_017341.1\|WP_000334465.1\|2300518_2302324_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_017341.1\|WP_000083807.1\|2303004_2304543_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NC_017341.1\|WP_000160304.1\|2285566_2286277_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NC_017341.1\|WP_000927363.1\|2304577_2306710_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67
NC_017341.1\|WP_001123303.1\|2287040_2287454_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NC_017341.1\|WP_000115564.1\|2296357_2297494_-\|SAP-domain-containing-protein	gnl\|CDD\|366887	pfam02037, SAP, SAP domain. The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.	3.91533e-06
NC_017341.1\|WP_000370924.1\|2298579_2299437_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	5.39747e-59
NC_017341.1\|WP_000908176.1\|2299504_2300287_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	4.88024e-103
NC_017341.1\|WP_000070866.1\|2286397_2286841_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NC_017341.1\|WP_000019744.1\|2292729_2293710_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.049e-108
NC_017341.1\|WP_001127960.1\|2290217_2291156_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129

>NC_017341.1|WP_000495671.1|2293975_2295067_+|lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NC_017341.1|WP_000019744.1|2292729_2293710_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NC_017341.1|WP_000003760.1|2292407_2292728_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKVLGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NC_017341.1|WP_001024106.1|2291590_2292256_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGYTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>NC_017341.1|WP_001127960.1|2290217_2291156_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NC_017341.1|WP_000808820.1|2289956_2290187_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHISQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NC_017341.1|WP_000123393.1|2287911_2289285_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRISNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NC_017341.1|WP_001123303.1|2287040_2287454_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NC_017341.1|WP_000070866.1|2286397_2286841_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NC_017341.1|WP_000160304.1|2285566_2286277_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NC_017341.1|WP_001802298.1|2295566_2295671_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NC_017341.1|WP_000115564.1|2296357_2297494_-|SAP-domain-containing-protein
MSVNARDLLVLHTNVNRLVGEEIFANKCLANNDVQIMNSIKKLIEAELLTTTNDFEVSIYKKTRPELQSILKSFGIKTTGNKPDLIKRIDDNFHIINNLDLPYVYIPTKKGEEILKKTEYLTSFIQSYGEISLERAYYLVENYIDENCDDKVAEIYKFEFQRKYDNGEFDFNHGYNFELNMLIDHYKRDVKDYDNARKYSNIYLYFGLRDFLKKLMSNYSYYDSKGNIDLNEIQNDLNRFINSSASGMYERLIYNENLSNNIMFELFKKDTQDYSDLEEQLIEKFINYVVSNVKKESRSNTLIELSKILENGYTIDKEEFKKEDDYLSKYIFTDIDYLKKLESKINVAIDIRSGEIHLVLDDDSLDILIQNQKYGNEF
>NC_017341.1|WP_001790138.1|2297782_2297875_+|hypothetical-protein
MFIFKTTSKSHFHNNVKSLECIKIPINKNR
>NC_017341.1|WP_000370924.1|2298579_2299437_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAEHFLAE
>NC_017341.1|WP_000908176.1|2299504_2300287_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMFAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NC_017341.1|WP_000334465.1|2300518_2302324_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NC_017341.1|WP_000083807.1|2303004_2304543_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NC_017341.1|WP_000927363.1|2304577_2306710_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NC_017341.1|WP_001292149.1|2306721_2307156_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NC_017341.1|WP_000648718.1|2307155_2308262_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

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Crispr_ID: NC_017341_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_10

2322304-2322431

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_10

>merge|NC_017341|10|2322304-2322431|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>NC_017341|10|10|2322304-2322431|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000648718.1\|2307155_2308262_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NC_017341.1\|WP_000147094.1\|2337226_2337742_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NC_017341.1\|WP_001251935.1\|2337918_2338179_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_001140999.1\|2331437_2332880_-\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NC_017341.1\|WP_001790708.1\|2329951_2330137_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000521491.1\|2316295_2317651_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NC_017341.1\|WP_000334465.1\|2300518_2302324_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_017341.1\|WP_000083807.1\|2303004_2304543_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NC_017341.1\|WP_031784974.1\|2322069_2322183_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000636857.1\|2333201_2333675_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NC_017341.1\|WP_000167867.1\|2319609_2320518_-\|arginase	unknown	unknown	gnl\|CDD\|212515
NC_017341.1\|WP_001237506.1\|2333773_2335117_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_017341.1\|WP_000347896.1\|2318611_2319421_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NC_017341.1\|WP_001549577.1\|2338310_2339681_-\|YjiH-family-protein	unknown	unknown	gnl\|CDD\|225851
NC_017341.1\|WP_000047255.1\|2335293_2335977_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NC_017341.1\|WP_000884739.1\|2335995_2337183_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NC_017341.1\|WP_001292149.1\|2306721_2307156_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NC_017341.1\|WP_000958531.1\|2330225_2331290_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NC_017341.1\|WP_000894032.1\|2317677_2318610_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NC_017341.1\|WP_000927363.1\|2304577_2306710_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000648718.1\|2307155_2308262_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_017341.1\|WP_000147094.1\|2337226_2337742_-\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.69656e-24
NC_017341.1\|WP_001140999.1\|2331437_2332880_-\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.50487e-81
NC_017341.1\|WP_000958531.1\|2330225_2331290_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NC_017341.1\|WP_000521491.1\|2316295_2317651_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NC_017341.1\|WP_000334465.1\|2300518_2302324_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_017341.1\|WP_000083807.1\|2303004_2304543_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NC_017341.1\|WP_000894032.1\|2317677_2318610_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NC_017341.1\|WP_000167867.1\|2319609_2320518_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	9.8301e-146
NC_017341.1\|WP_001237506.1\|2333773_2335117_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.92638e-43
NC_017341.1\|WP_000347896.1\|2318611_2319421_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NC_017341.1\|WP_001549577.1\|2338310_2339681_-\|YjiH-family-protein	gnl\|CDD\|225851	COG3314, COG3314, Uncharacterized protein conserved in bacteria [Function unknown].	4.43025e-139
NC_017341.1\|WP_000047255.1\|2335293_2335977_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NC_017341.1\|WP_000884739.1\|2335995_2337183_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.6491e-149
NC_017341.1\|WP_001292149.1\|2306721_2307156_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NC_017341.1\|WP_000636857.1\|2333201_2333675_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
NC_017341.1\|WP_000927363.1\|2304577_2306710_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.09729e-67

>NC_017341.1|WP_031784974.1|2322069_2322183_+|hypothetical-protein
MYFKNSSLNYIPTTFGGEPKETLFYKVSNTLCYVNNS
>NC_017341.1|WP_000167867.1|2319609_2320518_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NC_017341.1|WP_000347896.1|2318611_2319421_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NC_017341.1|WP_000894032.1|2317677_2318610_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NC_017341.1|WP_000521491.1|2316295_2317651_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIALDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NC_017341.1|WP_000648718.1|2307155_2308262_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVLAETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NC_017341.1|WP_001292149.1|2306721_2307156_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NC_017341.1|WP_000927363.1|2304577_2306710_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFISDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NC_017341.1|WP_000083807.1|2303004_2304543_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NC_017341.1|WP_000334465.1|2300518_2302324_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NC_017341.1|WP_001790708.1|2329951_2330137_-|hypothetical-protein
MLSNKRVEKEAGCEHKKFLKKLLTLNSKVDNMIKSSKTTQLFLKKNFKSVKLTIEITIKTI
>NC_017341.1|WP_000958531.1|2330225_2331290_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NC_017341.1|WP_001140999.1|2331437_2332880_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIAILAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALILSMVIIYLFIRRQFNITNALLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NC_017341.1|WP_000636857.1|2333201_2333675_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NC_017341.1|WP_001237506.1|2333773_2335117_-|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NC_017341.1|WP_000047255.1|2335293_2335977_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NC_017341.1|WP_000884739.1|2335995_2337183_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVRVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
>NC_017341.1|WP_000147094.1|2337226_2337742_-|metal-dependent-hydrolase
MTGKTHASCGMLVGALTTQYFQTDIFSSVTVIILATLASLLPDICHTQSKIGRRFKVISFFVRLIFGHRTFTHSILFIAIIAFLLQIIQTPNYYMAAIIIGLVSHVILDMITPKGVKLFYPLPFNVKTPIQFKTGGLVDLSLATALMVGTVYVLFQPFINDIISNWNTKFL
>NC_017341.1|WP_001251935.1|2337918_2338179_+|hypothetical-protein
MAMTVKKDNNEVRIQWRVADIKIPTSEIKNITQDQDIHAVPKLDSKDVSRIGSTFGKTNRVIIDTEDHEYIIYTQNDQKVYNELTK
>NC_017341.1|WP_001549577.1|2338310_2339681_-|YjiH-family-protein
MDSFSRKEIVIGRLKFITMSLIGILLFLVPIPVEQDGQKQTTLPVAFLAGVLKDVLGGVMPFLIVTIITLSGIITLICSTILKDKLKPDGLMNNAFNVRIGWLILRILAVVFAWMTFLRIGSKVIYSDETGGLLFSSLLPTLVAVFLFAALFLPLLMEYGLLEMLGPIFRPVMRPLFTLPGRSTVDNLASFIGDGTVGVLITSRQYGEGYYSRREATVISTTFSVVSITFAIVVAETVHMQNQFFAFYLSVIVSCLVAAVIMPRIWPLNKIPDEYAKEVPESARTEALPEGKTALRHGFDTATEVGIKAPGVIDFFKSGLKTVIDMWFVILPVVMSIGTIATIIANYTPFFVILGKPFVPFLELMQIPEAAQASQTIIIGFADMFLPSILIEGVQNDITRFVIGALSISQLIYLSEVGGVILGSKIPVSIGKLFMIFLIRTIITLPIISLMAHLLL

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Crispr_ID: NC_017341_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_11

2421118-2421311

Orphan

Consensus_repeat	Method
TGTTGGGGCCCCGCCAACTTGCA	CRT

3 spacers

The CRISPR arrays of NC_017341_11

>merge|NC_017341|11|2421118-2421311|CRT
TGTTGGGGCCCCGCCAACTTGCACATTATTGTATGCTGACTTTTCGTCACCTTCTGTGTTGGGGCCCCGTTCCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGTA

>NC_017341|11|1|2421118-2421311|CRT
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTATGCTGACTTTTCGTCACCTTCTG
TGTTGGGGCCCCGTTCCCCAACT	TGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTA
TGTTGGGGCCCCGCCAACTTGCA	CATTATTGTAAGCTGACTTTCTGTCAGCTTCTG
TGTTGGGGCCCCGCCAACTTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_000051206.1\|2411645_2411810_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000866971.1\|2423100_2423334_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NC_017341.1\|WP_000602937.1\|2423799_2424285_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NC_017341.1\|WP_000259718.1\|2424281_2425541_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NC_017341.1\|WP_000951058.1\|2418665_2419106_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NC_017341.1\|WP_000600967.1\|2417739_2418504_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NC_017341.1\|WP_000184419.1\|2419098_2420310_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NC_017341.1\|WP_000066900.1\|2420411_2420762_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NC_017341.1\|WP_000643988.1\|2422494_2423094_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NC_017341.1\|WP_001161085.1\|2412054_2412372_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000134528.1\|2425603_2426098_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NC_017341.1\|WP_000230173.1\|2421452_2422475_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NC_017341.1\|WP_000503817.1\|2426099_2426606_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NC_017341.1\|WP_000413865.1\|2415842_2417108_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NC_017341.1\|WP_000076929.1\|2426636_2427641_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NC_017341.1\|WP_001790034.1\|2420887_2421058_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000913019.1\|2427810_2428416_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NC_017341.1\|WP_000592303.1\|2412558_2415726_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_017341.1\|WP_001549681.1\|2417496_2417748_+\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000808500.1\|2423339_2423786_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000134528.1\|2425603_2426098_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	3.63862e-98
NC_017341.1\|WP_000866971.1\|2423100_2423334_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NC_017341.1\|WP_000602937.1\|2423799_2424285_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NC_017341.1\|WP_000259718.1\|2424281_2425541_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.49423e-160
NC_017341.1\|WP_000951058.1\|2418665_2419106_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NC_017341.1\|WP_000600967.1\|2417739_2418504_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NC_017341.1\|WP_000184419.1\|2419098_2420310_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
NC_017341.1\|WP_000808500.1\|2423339_2423786_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NC_017341.1\|WP_000643988.1\|2422494_2423094_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NC_017341.1\|WP_000066900.1\|2420411_2420762_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NC_017341.1\|WP_000230173.1\|2421452_2422475_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NC_017341.1\|WP_000503817.1\|2426099_2426606_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	1.02752e-64
NC_017341.1\|WP_000413865.1\|2415842_2417108_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	4.8324e-143
NC_017341.1\|WP_000076929.1\|2426636_2427641_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.67241e-132
NC_017341.1\|WP_000913019.1\|2427810_2428416_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NC_017341.1\|WP_000592303.1\|2412558_2415726_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0

>NC_017341.1|WP_001790034.1|2420887_2421058_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NC_017341.1|WP_000066900.1|2420411_2420762_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NC_017341.1|WP_000184419.1|2419098_2420310_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NC_017341.1|WP_000951058.1|2418665_2419106_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NC_017341.1|WP_000600967.1|2417739_2418504_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NC_017341.1|WP_001549681.1|2417496_2417748_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NC_017341.1|WP_000413865.1|2415842_2417108_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMKTSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NC_017341.1|WP_000592303.1|2412558_2415726_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NC_017341.1|WP_001161085.1|2412054_2412372_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NC_017341.1|WP_000051206.1|2411645_2411810_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDIEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NC_017341.1|WP_000230173.1|2421452_2422475_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NC_017341.1|WP_000643988.1|2422494_2423094_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NC_017341.1|WP_000866971.1|2423100_2423334_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NC_017341.1|WP_000808500.1|2423339_2423786_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NC_017341.1|WP_000602937.1|2423799_2424285_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NC_017341.1|WP_000259718.1|2424281_2425541_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NC_017341.1|WP_000134528.1|2425603_2426098_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NC_017341.1|WP_000503817.1|2426099_2426606_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIDGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NC_017341.1|WP_000076929.1|2426636_2427641_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKYRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NC_017341.1|WP_000913019.1|2427810_2428416_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Crispr_ID: NC_017341_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017341_12

2917634-2917717

Orphan

Consensus_repeat	Method
TTTCGAAATTCTCTGTGTTGGGACCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017341_12

>merge|NC_017341|12|2917634-2917717|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCCACACCCTAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCC

>NC_017341|12|11|2917634-2917717|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCC	ACACCCTAACTCGCATTGCCTGTAGAATTTCT
TTTCGAAATTCTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017341.1\|WP_001789343.1\|2923003_2923357_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
NC_017341.1\|WP_000790915.1\|2913362_2914112_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373922
NC_017341.1\|WP_000215590.1\|2918817_2919537_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NC_017341.1\|WP_000362509.1\|2921480_2922860_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NC_017341.1\|WP_001054111.1\|2915744_2916314_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_017341.1\|WP_000672024.1\|2911585_2911777_+\|peptide-resistance-ABC-transporter-activity-modulator-VraH	unknown	unknown	unknown
NC_017341.1\|WP_000240855.1\|2923476_2923614_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NC_017341.1\|WP_000249657.1\|2919536_2921414_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NC_017341.1\|WP_000586234.1\|2912863_2913361_-\|hypothetical-protein	unknown	unknown	unknown
NC_017341.1\|WP_000779134.1\|2916566_2916962_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NC_017341.1\|WP_000143675.1\|2909613_2911494_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	unknown	unknown	gnl\|CDD\|376899
NC_017341.1\|WP_000154161.1\|2908865_2909624_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	unknown	unknown	gnl\|CDD\|224059
NC_017341.1\|WP_000742839.1\|2917935_2918775_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_017341.1\|WP_001059079.1\|2915417_2915618_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_017341.1\|WP_000491382.1\|2917029_2917383_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NC_017341.1\|WP_000089284.1\|2914130_2914934_-\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173803

Protein	Function_ID	Function_description	E-value
NC_017341.1\|WP_000790915.1\|2913362_2914112_-\|hypothetical-protein	gnl\|CDD\|373922	pfam15526, Ntox21, Novel toxin 21. Bacterial genomes and plasmids encode a variety of peptide and protein toxins that mediate inter-bacterial competition. Bacteriocins are diffusible proteins that parasitize cell-envelope proteins to enter and kill bacteria. Contact-dependent growth inhibition (CDI) is one mechanism of inter-bacterial competition. Novel Toxin 21 (alternatively 16S rRNA endonuclease CdiA) belongs to a family of prokaryotic polymorphic toxin systems implicated in intra-specific conflicts. This RNase toxin found in bacterial polymorphic toxin systems, is proposed to adopt the BECR (Barnase-EndoU-ColicinE5/D-RelE) fold, with two conserved lysine residues and [DS]xDxxxH, RxG[ST] and RxxD motifs. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 4, type 5 or type 7 secretion systems. This is also referred to as the E. cloacae CdiAC. The CdiAC proteins carry a variety of sequence-diverse C-terminal domains, which represent a collection of distinct toxins. Many CdiA-CT toxins have nuclease activities. In accord with the structural homology, CdiA-CT cleaves 16S rRNA at the same site as colicin E3 and this nuclease activity is responsible for growth inhibition.	3.28374e-23
NC_017341.1\|WP_000362509.1\|2921480_2922860_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_017341.1\|WP_001054111.1\|2915744_2916314_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.78153e-16
NC_017341.1\|WP_001059079.1\|2915417_2915618_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.4289e-30
NC_017341.1\|WP_000240855.1\|2923476_2923614_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10
NC_017341.1\|WP_001789343.1\|2923003_2923357_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	3.11548e-51
NC_017341.1\|WP_000249657.1\|2919536_2921414_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_017341.1\|WP_000779134.1\|2916566_2916962_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	5.93989e-39
NC_017341.1\|WP_000143675.1\|2909613_2911494_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.91285e-06
NC_017341.1\|WP_000154161.1\|2908865_2909624_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	6.08455e-110
NC_017341.1\|WP_000742839.1\|2917935_2918775_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	4.59236e-111
NC_017341.1\|WP_000215590.1\|2918817_2919537_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	3.53317e-96
NC_017341.1\|WP_000491382.1\|2917029_2917383_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.35852e-38
NC_017341.1\|WP_000089284.1\|2914130_2914934_-\|S8-family-serine-peptidase	gnl\|CDD\|173803	cd07477, Peptidases_S8_Subtilisin_subset, Peptidase S8 family domain in Subtilisin proteins. This group is composed of many different subtilisins: Pro-TK-subtilisin, subtilisin Carlsberg, serine protease Pb92 subtilisin, and BPN subtilisins just to name a few. Pro-TK-subtilisin is a serine protease from the hyperthermophilic archaeon Thermococcus kodakaraensis and consists of a signal peptide, a propeptide, and a mature domain. TK-subtilisin is matured from pro-TK-subtilisin upon autoprocessing and degradation of the propeptide. Unlike other subtilisins though, the folding of the unprocessed form of pro-TK-subtilisin is induced by Ca2+ binding which is almost completed prior to autoprocessing. Ca2+ is required for activity unlike the bacterial subtilisins. The propeptide is not required for folding of the mature domain unlike the bacterial subtilases because of the stability produced from Ca2+ binding. Subtilisin Carlsberg is extremely similar in structure to subtilisin BPN'/Novo thought it has a 30% difference in amino acid sequence. The substrate binding regions are also similar and 2 possible Ca2+ binding sites have been identified recently. Subtilisin Carlsberg possesses the highest commercial importance as a proteolytic additive for detergents. Serine protease Pb92, the serine protease from the alkalophilic Bacillus strain PB92, also contains two calcium ions and the overall folding of the polypeptide chain closely resembles that of the subtilisins. Members of the peptidases S8 and S35 clan include endopeptidases, exopeptidases and also a tripeptidyl-peptidase. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The S53 family contains a catalytic triad Glu/Asp/Ser. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.02571e-48

>NC_017341.1|WP_000491382.1|2917029_2917383_-|DUF3147-family-protein
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYIKHKGYRKGAIFTVVCWFVISLAIFSIRHL
>NC_017341.1|WP_000779134.1|2916566_2916962_-|DUF3147-family-protein
MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKSNSK
>NC_017341.1|WP_001054111.1|2915744_2916314_-|helix-turn-helix-transcriptional-regulator
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCDLFNVTLDDLVKGTIPFAPDIKAQRSLNLWTYVMLIFMTLAAILTGPLVVYWNWAWGITVIVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTGVLSFIAFVGAIILIALISMHLANKFL
>NC_017341.1|WP_001059079.1|2915417_2915618_+|cold-shock-protein
MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEGQKVTFEITEGQRGDQAVNVQTV
>NC_017341.1|WP_000089284.1|2914130_2914934_-|S8-family-serine-peptidase
MSRNLIHLSIGVAIFIISFSFYLLNQPNNWAWSSLNICINDSKPSNVKVAILDTGINNTRINNNFVTKRYNAINNHNQITTDSNHATQVASIITYGEHKEKLIGISKSVSIYDVKVLDDNLKGDIDNIIKGITWSIKNDVNIIHMSFGFQRYNKELHDAIKNAKNKGIILVAAAGNNMDDYSDYPARFNEVYSITAIDKNNKPFIYAPTKKIDFKAPGVDVYTKGSKDELLTVNGTSFAAAYFTAYLTNNLEFRNDLPHILKEYPIK
>NC_017341.1|WP_000790915.1|2913362_2914112_-|hypothetical-protein
MKNKIIILFLAIIITFTYGNFAEASVVIKEANINNSNSKINTNKINENIYSKNNRNYIDNNFKSKDLNIESSLEHDLNTDKITVDASLKDNYNNKLDKTYDVKFLRIVNENDFKAEFTDQDTGEKIIYDTNEVKASIAPVVAVLVGFIAKQGLKKAIQKYGKTVVTSMIRTSPQVAAQAAKKLGYSATKHVSHGKKVFKKNSKGRPQYISVDKDGHRGGAWKGASSIKNLGSKKTRSGTYDANLKRIGD
>NC_017341.1|WP_000586234.1|2912863_2913361_-|hypothetical-protein
MIINLETQQIHFDLEHEIPYFQSPEKNRIRLDIDVLNKKQISNIINVIFNNQSKTKCTFLSEYLYPVKFREKTRIGRFFNITNWYEEIHSADEKYVIATIKNIKNKDLIDYSLYIKKGLVEPFIVFYNQENIFYISNAVIDIISVSKDTLGYIKSEFNDHCASPY
>NC_017341.1|WP_000672024.1|2911585_2911777_+|peptide-resistance-ABC-transporter-activity-modulator-VraH
MKFRELVKQSYEDLKNLTVTWYNVIALAIIVIVLSTVTTPIIGIPAGLLGGAYYLKRREEKGK
>NC_017341.1|WP_000143675.1|2909613_2911494_+|peptide-resistance-ABC-transporter-permease-subunit-VraE
MTFNHIVLKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFIITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTILMLIIAYILILFQSSLFLKRRSILSMMKDSVKTDVTTAKVTVIEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNDFNVVASQDAQQFESKLSQQHITFSKNYYETITVDNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNVINIHLNNDLVVKGTKNETFRVTQEDKDKVYPLNLSFNSPVIEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKKKAQAIAKQFGDKIITYDDMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>NC_017341.1|WP_000154161.1|2908865_2909624_+|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFHKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>NC_017341.1|WP_000742839.1|2917935_2918775_-|ParB/RepB/Spo0J-family-partition-protein
MKKPFSKLFGLKNKDDIIGHIEENRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFEQDVTQARDEVGKSIQAIQQIGLHVEHKDKDHEDYYEIKIRIYKR
>NC_017341.1|WP_000215590.1|2918817_2919537_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNYLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>NC_017341.1|WP_000249657.1|2919536_2921414_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>NC_017341.1|WP_000362509.1|2921480_2922860_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>NC_017341.1|WP_001789343.1|2923003_2923357_-|ribonuclease-P-protein-component
MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>NC_017341.1|WP_000240855.1|2923476_2923614_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017341_5	5.1\|900203\|34\|NC_017341\|CRISPRCasFinder	900203-900236	34	NC_017341.1	1395539-1395572	0	1.0
NC_017341_5	5.1\|900203\|34\|NC_017341\|CRISPRCasFinder	900203-900236	34	NC_017341.1	1487388-1487421	0	1.0
NC_017341_11	11.2\|2421197\|36\|NC_017341\|CRT	2421197-2421232	36	NC_017341.1	1184846-1184881	0	1.0
NC_017341_7	7.1\|1184945\|26\|NC_017341\|CRISPRCasFinder	1184945-1184970	26	NC_017341.1	287047-287072	1	0.962
NC_017341_7	7.1\|1184945\|26\|NC_017341\|CRISPRCasFinder	1184945-1184970	26	NC_017341.1	812030-812055	1	0.962
NC_017341_11	11.2\|2421197\|36\|NC_017341\|CRT	2421197-2421232	36	NC_017341.1	1853651-1853686	1	0.972
NC_017341_12	12.1\|2917660\|32\|NC_017341\|CRISPRCasFinder	2917660-2917691	32	NC_017341.1	850505-850536	1	0.969
NC_017341_12	12.1\|2917660\|32\|NC_017341\|CRISPRCasFinder	2917660-2917691	32	NC_017341.1	1110586-1110617	1	0.969
NC_017341_12	12.1\|2917660\|32\|NC_017341\|CRISPRCasFinder	2917660-2917691	32	NC_017341.1	1487478-1487509	1	0.969
NC_017341_4	4.1\|850369\|26\|NC_017341\|CRISPRCasFinder	850369-850394	26	NC_017341.1	287047-287072	2	0.923
NC_017341_4	4.1\|850369\|26\|NC_017341\|CRISPRCasFinder	850369-850394	26	NC_017341.1	812030-812055	2	0.923
NC_017341_4	4.1\|850369\|26\|NC_017341\|CRISPRCasFinder	850369-850394	26	NC_017341.1	964311-964336	2	0.923
NC_017341_7	7.1\|1184945\|26\|NC_017341\|CRISPRCasFinder	1184945-1184970	26	NC_017341.1	812086-812111	2	0.923
NC_017341_11	11.1\|2421141\|33\|NC_017341\|CRT	2421141-2421173	33	NC_017341.1	1184902-1184934	2	0.939
NC_017341_11	11.1\|2421141\|33\|NC_017341\|CRT	2421141-2421173	33	NC_017341.1	1395494-1395526	2	0.939
NC_017341_11	11.1\|2421141\|33\|NC_017341\|CRT	2421141-2421173	33	NC_017341.1	1487434-1487466	2	0.939
NC_017341_11	11.1\|2421141\|33\|NC_017341\|CRT	2421141-2421173	33	NC_017341.1	2031594-2031626	2	0.939
NC_017341_11	11.1\|2421141\|33\|NC_017341\|CRT	2421141-2421173	33	NC_017341.1	2695148-2695180	2	0.939
NC_017341_11	11.2\|2421197\|36\|NC_017341\|CRT	2421197-2421232	36	NC_017341.1	287172-287207	2	0.944
NC_017341_11	11.2\|2421197\|36\|NC_017341\|CRT	2421197-2421232	36	NC_017341.1	1666491-1666526	2	0.944
NC_017341_11	11.2\|2421197\|36\|NC_017341\|CRT	2421197-2421232	36	NC_017341.1	2042338-2042373	2	0.944
NC_017341_11	11.3\|2421256\|33\|NC_017341\|CRT	2421256-2421288	33	NC_017341.1	1184902-1184934	2	0.939
NC_017341_11	11.3\|2421256\|33\|NC_017341\|CRT	2421256-2421288	33	NC_017341.1	1395494-1395526	2	0.939
NC_017341_11	11.3\|2421256\|33\|NC_017341\|CRT	2421256-2421288	33	NC_017341.1	2031594-2031626	2	0.939
NC_017341_11	11.3\|2421256\|33\|NC_017341\|CRT	2421256-2421288	33	NC_017341.1	2695148-2695180	2	0.939

1. spacer 5.1|900203|34|NC_017341|CRISPRCasFinder matches to position: 1395539-1395572, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

2. spacer 5.1|900203|34|NC_017341|CRISPRCasFinder matches to position: 1487388-1487421, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

3. spacer 11.2|2421197|36|NC_017341|CRT matches to position: 1184846-1184881, mismatch: 0, identity: 1.0

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttctttttgaaattctcta	Protospacer
************************************

4. spacer 7.1|1184945|26|NC_017341|CRISPRCasFinder matches to position: 287047-287072, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cgggcccccaacatagaagctggcgg	Protospacer
**** *********************

5. spacer 7.1|1184945|26|NC_017341|CRISPRCasFinder matches to position: 812030-812055, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagcaggcgg	Protospacer
******************** *****

6. spacer 11.2|2421197|36|NC_017341|CRT matches to position: 1853651-1853686, mismatch: 1, identity: 0.972

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

7. spacer 12.1|2917660|32|NC_017341|CRISPRCasFinder matches to position: 850505-850536, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

8. spacer 12.1|2917660|32|NC_017341|CRISPRCasFinder matches to position: 1110586-1110617, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

9. spacer 12.1|2917660|32|NC_017341|CRISPRCasFinder matches to position: 1487478-1487509, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

10. spacer 4.1|850369|26|NC_017341|CRISPRCasFinder matches to position: 287047-287072, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctatgttgggggcccg	Protospacer
************.******** ****

11. spacer 4.1|850369|26|NC_017341|CRISPRCasFinder matches to position: 812030-812055, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgcctgcttctatgttggggccccg	Protospacer
***** ******.*************

12. spacer 4.1|850369|26|NC_017341|CRISPRCasFinder matches to position: 964311-964336, mismatch: 2, identity: 0.923

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccaccagcctctgtgttggggccccg	Protospacer
**.*****.*****************

13. spacer 7.1|1184945|26|NC_017341|CRISPRCasFinder matches to position: 812086-812111, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacataaaagcaggcgg	Protospacer
***************.**** *****

14. spacer 11.1|2421141|33|NC_017341|CRT matches to position: 1184902-1184934, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

15. spacer 11.1|2421141|33|NC_017341|CRT matches to position: 1395494-1395526, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

16. spacer 11.1|2421141|33|NC_017341|CRT matches to position: 1487434-1487466, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcatcttctg	Protospacer
********** ***************.******

17. spacer 11.1|2421141|33|NC_017341|CRT matches to position: 2031594-2031626, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

18. spacer 11.1|2421141|33|NC_017341|CRT matches to position: 2695148-2695180, mismatch: 2, identity: 0.939

cattattgtatgctgacttttcgtcaccttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********** *************** ******

19. spacer 11.2|2421197|36|NC_017341|CRT matches to position: 287172-287207, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

20. spacer 11.2|2421197|36|NC_017341|CRT matches to position: 1666491-1666526, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaattctcta	Protospacer
*******.****************.***********

21. spacer 11.2|2421197|36|NC_017341|CRT matches to position: 2042338-2042373, mismatch: 2, identity: 0.944

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcctttcgaaattctcta	Protospacer
********************.***.***********

22. spacer 11.3|2421256|33|NC_017341|CRT matches to position: 1184902-1184934, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

23. spacer 11.3|2421256|33|NC_017341|CRT matches to position: 1395494-1395526, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

24. spacer 11.3|2421256|33|NC_017341|CRT matches to position: 2031594-2031626, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

25. spacer 11.3|2421256|33|NC_017341|CRT matches to position: 2695148-2695180, mismatch: 2, identity: 0.939

cattattgtaagctgactttctgtcagcttctg	CRISPR spacer
cattattgtaagctgacttttcgtcagcttctg	Protospacer
********************..***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017341_4	4.1\|850369\|26\|NC_017341\|CRISPRCasFinder	850369-850394	26	NZ_CP022541	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence	333735-333760	5	0.808
NC_017341_4	4.1\|850369\|26\|NC_017341\|CRISPRCasFinder	850369-850394	26	NZ_CP034332	Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence	3359-3384	5	0.808
NC_017341_4	4.1\|850369\|26\|NC_017341\|CRISPRCasFinder	850369-850394	26	NZ_CP022605	Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence	715511-715536	5	0.808

1. spacer 4.1|850369|26|NC_017341|CRISPRCasFinder matches to NZ_CP022541 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
acgccagcttctgtgttgaggcctta	Protospacer
 *****************.****...

2. spacer 4.1|850369|26|NC_017341|CRISPRCasFinder matches to NZ_CP034332 (Tabrizicola piscis strain K13M18 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtctgggcctac	Protospacer
****************. *****.

3. spacer 4.1|850369|26|NC_017341|CRISPRCasFinder matches to NZ_CP022605 (Ochrobactrum quorumnocens strain A44 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

ccgccagcttctgtgttggggccccg	CRISPR spacer
ccgccagcttctgtgtttggccctga	Protospacer
***************** ** **. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

389017 : 404610

Staphylococcus_phage(75.0%)

terminase,integrase,coat

attL 390553:390574|attR 405317:405338

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001052483.1\|389017_389209_-	hypothetical protein	U3PCX8	Staphylococcus_phage	4.9e-23	80.0
WP_001261460.1\|389452_389749_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_000934798.1\|389769_390273_+	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	3.5e-60	74.1
WP_000897044.1\|390324_390567_+	30S ribosomal protein S18	NA	NA	NA	NA
390553:390574	attL	NA	NA	NA	NA
WP_001800370.1\|390798_391593_-	type II toxin-antitoxin system PemK/MazF family toxin	Q4ZE81	Staphylococcus_phage	5.6e-28	30.0
WP_000270135.1\|391630_392845_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	3.3e-221	97.3
WP_000230361.1\|393005_393629_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001611932.1\|393777_393942_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001138305.1\|393942_394215_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	1.2e-43	94.4
WP_000784892.1\|394226_394400_+	hypothetical protein	NA	NA	NA	NA
WP_001231376.1\|394366_394570_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	2.0e-30	98.5
WP_000403839.1\|394571_394955_+	hypothetical protein	A0A1W6JQI7	Staphylococcus_phage	9.7e-63	96.1
WP_001103965.1\|394955_395282_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.8e-54	98.1
WP_001002722.1\|395346_396216_+	primase alpha helix C-terminal domain-containing protein	A0A2H4JEH3	uncultured_Caudovirales_phage	2.2e-131	75.8
WP_000151864.1\|396227_397598_+	DNA primase family protein	A0A2H4JBE3	uncultured_Caudovirales_phage	2.4e-257	95.0
WP_001059599.1\|397840_398197_+	hypothetical protein	A0A2H4JBD4	uncultured_Caudovirales_phage	3.0e-50	78.8
WP_001003076.1\|398198_398462_+	hypothetical protein	NA	NA	NA	NA
WP_001019280.1\|398463_399105_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	8.5e-112	94.8
WP_001190614.1\|399640_399982_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	2.9e-58	100.0
WP_000214170.1\|400012_400666_+	hypothetical protein	Q4ZE82	Staphylococcus_phage	7.6e-116	99.5
WP_000771359.1\|400718_401246_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	1.9e-88	97.1
WP_025174984.1\|401377_401590_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	3.2e-31	97.1
WP_001281787.1\|401586_402156_+\|terminase	terminase small subunit	A0A1W6JQF0	Staphylococcus_phage	4.6e-101	97.9
WP_000801982.1\|402432_403401_+	Abi family protein	A0A0H4U080	Erysipelothrix_phage	5.9e-24	27.3
WP_073392942.1\|403542_403980_+	DUF3102 domain-containing protein	A0A2H4JAH5	uncultured_Caudovirales_phage	9.8e-27	58.2
WP_000813311.1\|404097_404610_+	hypothetical protein	Q4ZE83	Staphylococcus_phage	1.4e-69	100.0
405317:405338	attR	NA	NA	NA	NA

DBSCAN-SWA_2

423799 : 439812

Streptococcus_phage(76.92%)

integrase

attL 419707:419721|attR 435636:435650

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
419707:419721	attL	NA	NA	NA	NA
WP_000264071.1\|423799_425266_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
WP_000424966.1\|425290_426832_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
WP_000237796.1\|426899_428093_-\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	8.3e-44	34.2
WP_000633907.1\|428119_428320_-	DUF3173 domain-containing protein	NA	NA	NA	NA
WP_000845143.1\|428817_429048_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	1.0e-27	78.9
WP_000804879.1\|429044_429467_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	7.5e-48	68.6
WP_001227350.1\|429997_430351_+	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	2.2e-53	89.7
WP_032506803.1\|430408_430597_-	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	7.4e-16	61.4
WP_000691737.1\|430694_432614_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.2
WP_001791010.1\|432629_432746_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000584387.1\|432990_433920_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-83	56.6
WP_000768373.1\|433936_434959_-	bifunctional lysozyme/C40 family peptidase	A0A1S5SEZ8	Streptococcus_phage	2.4e-132	75.5
WP_000192392.1\|434955_436983_-	membrane protein	A0A1S5SF30	Streptococcus_phage	2.3e-195	65.5
435636:435650	attR	NA	NA	NA	NA
WP_000331166.1\|436979_439433_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	78.7
WP_000723887.1\|439416_439812_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	5.9e-47	72.6

DBSCAN-SWA_3

442964 : 451131

Streptococcus_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000870467.1\|442964_443459_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	2.8e-54	63.4
WP_000675717.1\|443525_444305_-	abortive infection family protein	NA	NA	NA	NA
WP_001009054.1\|444346_444568_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	3.1e-29	93.2
WP_000055376.1\|444564_444855_-	hypothetical protein	NA	NA	NA	NA
WP_000426690.1\|444851_446036_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	8.3e-161	68.1
WP_001130246.1\|446217_447621_-	DUF87 domain-containing protein	A0A1S5SFB5	Streptococcus_phage	1.4e-175	66.5
WP_000185762.1\|447642_448416_-	hypothetical protein	NA	NA	NA	NA
WP_001234191.1\|448425_448803_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	9.6e-47	76.4
WP_000421279.1\|448823_449138_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	1.2e-42	77.7
WP_000181735.1\|449337_451131_-	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	6.9e-26	23.8

DBSCAN-SWA_4

780567 : 788387

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244412.1\|780567_781623_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	2.1e-14	30.0
WP_000149344.1\|781622_782309_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|782283_782757_-	DoxX family protein	NA	NA	NA	NA
WP_001093553.1\|783098_783539_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637687.1\|783818_784403_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|784501_785215_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|785218_785638_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|785639_786308_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604514.1\|786658_787252_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217785.1\|787235_788387_+	anthranilate synthase component I family protein	A0A0B5J984	Pandoravirus	1.6e-23	35.7

DBSCAN-SWA_5

800359 : 815188

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|800359_801418_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197271.1\|801768_802311_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429014.1\|802990_803908_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.0
WP_001790641.1\|803998_804100_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|804177_805683_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|806023_806524_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|806543_807410_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|808210_808609_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|808571_810677_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|810794_811766_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|812321_812477_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|812515_813487_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|813473_814430_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616842.1\|814426_815188_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_6

893231 : 916548

Staphylococcus_phage(80.95%)

terminase,integrase,coat,transposase

attL 904276:904294|attR 918837:918855

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000868132.1\|893231_894317_+\|integrase	tyrosine-type recombinase/integrase	A0A0A8WIF9	Clostridium_phage	4.5e-12	28.3
WP_001557544.1\|894313_896206_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_000361059.1\|896212_896590_+\|transposase	transposase	NA	NA	NA	NA
WP_000067268.1\|896740_897523_+	aminoglycoside nucleotidyltransferase ANT(9)-Ia	NA	NA	NA	NA
WP_001072197.1\|897648_898380_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	E4ZFQ0	Streptococcus_phage	4.2e-54	48.8
WP_181875734.1\|898437_898497_-	erythromycin resistance leader peptide	NA	NA	NA	NA
WP_001092058.1\|898888_899551_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_001018962.1\|900816_901203_+	topiosmerase	NA	NA	NA	NA
WP_001065801.1\|901195_901492_+	thioredoxin family protein	NA	NA	NA	NA
WP_000571218.1\|901741_902767_+	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-27	36.8
WP_000520233.1\|902759_903455_+	ABC transporter permease	NA	NA	NA	NA
WP_000732326.1\|903472_904294_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
904276:904294	attL	NA	NA	NA	NA
WP_000264182.1\|904437_905658_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	3.5e-98	47.3
WP_000733773.1\|905745_906474_-	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	2.4e-22	32.3
WP_001033317.1\|906497_907226_-	staphylococcal enterotoxin type Q	A0EX09	Staphylococcus_phage	7.9e-29	35.4
WP_000142630.1\|907400_908135_-	helix-turn-helix transcriptional regulator	Q4ZE79	Staphylococcus_phage	8.5e-132	98.4
WP_001063624.1\|908284_908497_+	helix-turn-helix transcriptional regulator	Q4ZE78	Staphylococcus_phage	3.4e-33	98.6
WP_001138298.1\|908497_908770_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	3.4e-46	100.0
WP_000784885.1\|908781_908928_+	hypothetical protein	NA	NA	NA	NA
WP_001058492.1\|908920_909130_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	7.7e-30	95.7
WP_001103946.1\|909132_909426_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	1.8e-24	61.8
WP_001002692.1\|909513_910383_+	primase alpha helix C-terminal domain-containing protein	A0A1W6JQL5	Staphylococcus_phage	3.8e-163	97.2
WP_000432707.1\|910399_911857_+	hypothetical protein	A0A1W6JQD6	Staphylococcus_phage	1.4e-279	96.7
WP_001039172.1\|912158_912521_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	2.9e-64	96.7
WP_000998180.1\|912522_912807_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.6e-49	98.9
WP_001019783.1\|912803_913445_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	2.7e-113	94.8
WP_041174166.1\|913871_914234_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	2.3e-53	98.1
WP_000846279.1\|914245_914824_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	3.3e-30	40.0
WP_000448776.1\|914841_915060_+	hypothetical protein	NA	NA	NA	NA
WP_000771365.1\|915110_915638_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	1.6e-87	96.0
WP_025174984.1\|915769_915982_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	3.2e-31	97.1
WP_001281786.1\|915978_916548_+\|terminase	terminase small subunit	A0A1W6JQF0	Staphylococcus_phage	1.2e-101	98.4
918837:918855	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1009414 : 1050492

Streptococcus_phage(40.0%)

transposase,bacteriocin,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000448927.1\|1009414_1010404_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|1010698_1011094_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001217730.1\|1011464_1012184_+	adaptor protein MecA	NA	NA	NA	NA
WP_000082731.1\|1013337_1015146_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	9.3e-47	24.4
WP_000896697.1\|1015605_1016412_-\|protease	protease adaptor protein YjbH	NA	NA	NA	NA
WP_000214065.1\|1016434_1016800_-	truncated hemoglobin	NA	NA	NA	NA
WP_000224622.1\|1016903_1017497_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242102.1\|1017682_1018030_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|1018046_1018682_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|1018698_1019508_+	NAD kinase	NA	NA	NA	NA
WP_000669939.1\|1019504_1020359_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000062417.1\|1020379_1021765_+	magnesium transporter	NA	NA	NA	NA
WP_000395155.1\|1021774_1023619_+	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_000195429.1\|1023900_1025073_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000933195.1\|1025228_1025999_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933105.1\|1026193_1027279_-	AI-2E family transporter	NA	NA	NA	NA
WP_000570698.1\|1027620_1029189_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_001288681.1\|1029330_1030089_+	esterase family protein	NA	NA	NA	NA
WP_000600392.1\|1030282_1030792_+	2'-5' RNA ligase family protein	NA	NA	NA	NA
WP_001154222.1\|1030904_1032095_-	MFS transporter	NA	NA	NA	NA
WP_000258650.1\|1032072_1033248_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_000340118.1\|1033680_1035162_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_001795833.1\|1035145_1035406_+	YueH family protein	NA	NA	NA	NA
WP_001049959.1\|1035405_1036968_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	4.9e-36	28.2
WP_000928413.1\|1037269_1038073_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_014532858.1\|1038291_1040616_+\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.4
WP_000021864.1\|1040632_1041991_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000414177.1\|1042129_1043641_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287265.1\|1044127_1044697_-	competence protein ComK	NA	NA	NA	NA
WP_000876826.1\|1044906_1045125_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000668820.1\|1045205_1046192_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|1046390_1046567_+	YkvS family protein	NA	NA	NA	NA
WP_001033867.1\|1046581_1047184_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001790623.1\|1048100_1048202_+	hypothetical protein	NA	NA	NA	NA
WP_001790097.1\|1048211_1048484_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000870806.1\|1048527_1050492_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA

DBSCAN-SWA_8

1085850 : 1094323

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1085850_1086333_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010412.1\|1086319_1087444_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1087447_1088152_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1088151_1088415_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1088416_1089088_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032727.1\|1089080_1091270_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483713.1\|1091248_1092733_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030812.1\|1092725_1093754_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238664.1\|1093756_1094323_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1

DBSCAN-SWA_9

1715560 : 1724603

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1715560_1716079_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594994.1\|1716100_1718374_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.9e-63	28.8
WP_000749795.1\|1718576_1720856_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1721130_1721391_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112046.1\|1721409_1722549_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.4e-85	45.2
WP_001019172.1\|1722571_1723597_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1723598_1724603_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_10

1834802 : 1913682

Staphylococcus_phage(89.36%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000195429.1\|1834802_1835975_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001791758.1\|1836249_1836354_-	hypothetical protein	NA	NA	NA	NA
WP_000193898.1\|1836488_1837688_-	membrane protein	NA	NA	NA	NA
WP_000383814.1\|1837761_1838253_-	DUF948 domain-containing protein	NA	NA	NA	NA
WP_000150163.1\|1838326_1839640_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_000118291.1\|1839663_1843488_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.6e-83	47.0
WP_001048363.1\|1843508_1844105_-\|tRNA	DUF4479 domain-containing tRNA-binding protein	NA	NA	NA	NA
WP_001091387.1\|1844133_1844991_-	DUF1444 domain-containing protein	A0A2H4PQY3	Staphylococcus_phage	6.8e-72	100.0
WP_000811163.1\|1845090_1845402_-	thioredoxin family protein	NA	NA	NA	NA
WP_001024576.1\|1845466_1846543_-	M42 family metallopeptidase	NA	NA	NA	NA
WP_000163826.1\|1846629_1846941_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_000689580.1\|1847065_1847908_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_000093392.1\|1848432_1848918_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
WP_001266157.1\|1849119_1849764_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_000434765.1\|1849778_1850570_-	phosphotransferase family protein	NA	NA	NA	NA
WP_000411085.1\|1851119_1851968_-	D-amino-acid transaminase	NA	NA	NA	NA
WP_000265417.1\|1851971_1853381_-	Mn(2+)-dependent dipeptidase Sapep	NA	NA	NA	NA
WP_001051859.1\|1854138_1854516_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_001217125.1\|1854532_1855228_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000004335.1\|1855224_1856886_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_000285019.1\|1857292_1858561_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	4.1e-57	100.0
WP_001050548.1\|1858677_1865238_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	2.0e-304	98.1
WP_000836465.1\|1865563_1865875_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001549041.1\|1865896_1868314_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
WP_001025061.1\|1868601_1869783_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526539.1\|1869892_1870846_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1870842_1871406_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1871525_1871927_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1873507_1874335_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1874337_1874457_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1874568_1875570_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|1875691_1876156_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159024.1\|1876168_1877350_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.6e-225	99.2
WP_000493892.1\|1877360_1877993_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_000077335.1\|1877999_1879043_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.3e-197	99.1
WP_001261677.1\|1879523_1881026_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000221179.1\|1881548_1881863_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989121.1\|1881862_1883155_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_000163235.1\|1883172_1883568_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
WP_001032833.1\|1883862_1884717_-	N-acetylglucosaminidase	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1884992_1885217_-	hypothetical protein	NA	NA	NA	NA
WP_000195429.1\|1885329_1886502_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001096491.1\|1887577_1888291_-	transaldolase	M1PR54	Cyanophage	1.2e-18	35.3
WP_000091445.1\|1888550_1888853_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1889108_1889474_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623471.1\|1889470_1889824_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000195429.1\|1891002_1892175_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000671052.1\|1892420_1892891_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1893003_1893447_+	competence protein ComK	NA	NA	NA	NA
WP_001030465.1\|1893433_1893877_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.0e-55	85.0
WP_000195429.1\|1894331_1895504_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000453320.1\|1896567_1897401_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-156	98.6
WP_000366154.1\|1897612_1898521_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.2e-136	98.7
WP_000933822.1\|1898645_1899839_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109900.1\|1900209_1901802_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_000093392.1\|1901937_1902423_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	4.9e-19	35.4
WP_078055878.1\|1902797_1903544_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.1e-141	98.0
WP_000672014.1\|1903548_1904022_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_000718107.1\|1904087_1904345_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778523.1\|1904341_1905343_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	4.8e-186	97.6
WP_000348360.1\|1905347_1906826_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.0e-281	97.0
WP_011443643.1\|1906984_1907440_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.0e-79	98.6
WP_001795535.1\|1907742_1908393_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_000070653.1\|1908473_1909469_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	7.1e-73	96.4
WP_000669046.1\|1909544_1910171_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	7.1e-79	82.7
WP_000627551.1\|1910211_1910556_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	6.3e-53	92.0
WP_000414205.1\|1910653_1911205_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.0e-20	94.1
WP_000494956.1\|1911422_1912064_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.6e-76	93.2
WP_000809857.1\|1912177_1912363_-	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|1912364_1912541_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1912551_1912935_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|1913538_1913682_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0

DBSCAN-SWA_11

1946703 : 2021560

Staphylococcus_phage(80.95%)

terminase,integrase,portal,transposase,tail,capsid,holin,tRNA,head,plate

attL 1989296:1989313|attR 2025024:2025041

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181398.1\|1946703_1947174_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_000379978.1\|1947178_1948306_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_000590809.1\|1948456_1949179_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	42.7
WP_000649907.1\|1949171_1950629_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_000063582.1\|1950886_1951948_-	PTS transporter subunit IIC	NA	NA	NA	NA
WP_001549130.1\|1952440_1953802_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_031784974.1\|1953777_1953891_+	hypothetical protein	NA	NA	NA	NA
WP_000110013.1\|1962216_1962663_-	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
WP_000869455.1\|1962759_1963710_-	phosphoglycerate dehydrogenase	NA	NA	NA	NA
WP_000939521.1\|1963715_1964171_-	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_001011598.1\|1964251_1965541_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_001236371.1\|1965833_1966928_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_001791878.1\|1967017_1967110_-	hypothetical protein	NA	NA	NA	NA
WP_000597238.1\|1967118_1968855_-	SAV1866 family putative multidrug efflux ABC transporter	W8CYL7	Bacillus_phage	1.7e-53	30.4
WP_000251253.1\|1969145_1969688_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_000284752.1\|1969989_1971027_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000379098.1\|1971178_1972156_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_000886468.1\|1972416_1973253_-	membrane protein	NA	NA	NA	NA
WP_000535834.1\|1973261_1974779_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000435806.1\|1974793_1975108_-	YfhH family protein	NA	NA	NA	NA
WP_001124419.1\|1975085_1975904_-	recombination regulator RecX	NA	NA	NA	NA
WP_000830380.1\|1976164_1976974_-	monofunctional peptidoglycan glycosyltransferase SgtB	NA	NA	NA	NA
WP_000163283.1\|1977314_1977830_-	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_001005408.1\|1977960_1978122_-	hypothetical protein	NA	NA	NA	NA
WP_100250272.1\|1978468_1978549_+	hypothetical protein	NA	NA	NA	NA
WP_001148138.1\|1979135_1980581_-	SH3 domain-containing protein	Q4ZB16	Staphylococcus_virus	1.0e-293	98.5
WP_000354132.1\|1980561_1980999_-\|holin	phage holin	A0A2H4PQP0	Staphylococcus_phage	4.1e-73	100.0
WP_000677972.1\|1981054_1981450_-	hypothetical protein	Q4ZBW9	Staphylococcus_virus	6.1e-68	99.2
WP_000276669.1\|1981455_1982628_-\|plate	BppU family phage baseplate upper protein	A0EWN2	Staphylococcus_virus	1.2e-196	99.0
WP_000524037.1\|1982640_1984515_-	glucosaminidase domain-containing protein	Q4ZBX1	Staphylococcus_virus	0.0e+00	99.7
WP_000466769.1\|1984651_1984951_-	DUF2951 domain-containing protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
WP_001790193.1\|1984991_1985165_-	XkdX family protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
WP_000705893.1\|1985168_1985546_-	DUF2977 domain-containing protein	Q8LTH7	Staphylococcus_phage	7.3e-55	100.0
WP_000634520.1\|1985545_1987369_-\|plate	phage baseplate upper protein	A0A0F6N3G2	Staphylococcus_phage	0.0e+00	99.8
WP_000323261.1\|1987368_1989267_-	hypothetical protein	Q4ZBQ2	Staphylococcus_phage	0.0e+00	99.8
WP_001144703.1\|1989279_1991166_-\|tail	phage tail protein	A0A2I6PCV9	Staphylococcus_phage	0.0e+00	99.4
1989296:1989313	attL	NA	NA	NA	NA
WP_000560193.1\|1991176_1992112_-\|tail	phage tail family protein	A7YGW1	Staphylococcus_virus	4.5e-178	98.7
WP_000414232.1\|1992126_1995096_-\|terminase	terminase	A0A2H4PQM1	Staphylococcus_phage	2.6e-264	98.9
WP_000204080.1\|1995098_1995440_-	hypothetical protein	A0A2H4PQL5	Staphylococcus_phage	7.8e-56	99.1
WP_000141081.1\|1995460_1995955_-	hypothetical protein	A0A0H4IPX9	Staphylococcus_phage	1.2e-86	99.4
WP_000046067.1\|1996016_1996577_-	hypothetical protein	A0A0H4ITY2	Staphylococcus_phage	5.9e-101	100.0
WP_000270196.1\|1996563_1997001_-	DUF3168 domain-containing protein	A0A0E3T9M9	Staphylococcus_phage	2.1e-77	100.0
WP_001151331.1\|1997013_1997427_-	HK97 gp10 family phage protein	A0A0E3XCY8	Staphylococcus_phage	4.4e-77	99.3
WP_000482985.1\|1997413_1997749_-\|head	phage head closure protein	A0A0H4ISR6	Staphylococcus_phage	1.4e-60	99.1
WP_000991902.1\|1997741_1998056_-\|head,tail	phage head-tail connector protein	A0A2H4PQL2	Staphylococcus_phage	9.8e-53	99.0
WP_000278798.1\|1998055_1998382_-	Rho termination factor N-terminal domain-containing protein	A0A2H4PQK8	Staphylococcus_phage	4.7e-50	98.1
WP_001135557.1\|1998398_1999223_-\|capsid	N4-gp56 family major capsid protein	R4IH32	Staphylococcus_phage	1.6e-147	99.6
WP_000366933.1\|1999243_1999840_-	phage scaffolding protein	A0A0H4IP83	Staphylococcus_phage	1.7e-77	79.3
WP_049772008.1\|1999937_2000918_-\|head	phage head morphogenesis protein	A0A2H4PQJ8	Staphylococcus_phage	2.9e-180	99.1
WP_001159671.1\|2000856_2002335_-\|portal	phage portal protein	A0A0E3T8M2	Staphylococcus_phage	1.1e-284	99.4
WP_001791146.1\|2002288_2003497_-\|terminase	PBSX family phage terminase large subunit	R4IG95	Staphylococcus_phage	4.0e-235	99.8
WP_000594083.1\|2003489_2003984_-\|terminase	terminase small subunit	A0A2I6PCU5	Staphylococcus_phage	4.9e-83	99.4
WP_000286968.1\|2004338_2004740_-	hypothetical protein	A0A2H4PQK5	Staphylococcus_phage	5.6e-69	100.0
WP_000595256.1\|2004740_2004914_-	transcriptional activator RinB	A0A0H3U4U1	Staphylococcus_phage	9.8e-23	100.0
WP_000195784.1\|2004910_2005117_-	DUF1381 domain-containing protein	A0A2I6PEA2	Staphylococcus_phage	1.1e-17	94.1
WP_001282077.1\|2005113_2005359_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	2.5e-35	98.8
WP_000185680.1\|2005395_2005932_-	dUTP diphosphatase	A0A1P8L6E0	Staphylococcus_phage	2.1e-95	100.0
WP_001065023.1\|2005936_2006173_-	DUF1024 family protein	C8CH04	Staphylococcus_phage	1.1e-35	100.0
WP_001105618.1\|2006165_2006450_-	hypothetical protein	S4V9L1	Staphylococcus_phage	3.2e-47	100.0
WP_000695766.1\|2006446_2006848_-	hypothetical protein	S4V6D5	Staphylococcus_phage	2.1e-68	99.2
WP_000228426.1\|2006860_2007103_-	hypothetical protein	A0A2D1G5G2	Staphylococcus_phage	1.2e-39	97.5
WP_001187254.1\|2007720_2007906_-	DUF3113 family protein	Q4ZA46	Staphylococcus_virus	4.1e-27	100.0
WP_000049777.1\|2007910_2008315_-	DUF1064 domain-containing protein	Q6R835	Staphylococcus_virus	2.3e-70	98.5
WP_001123680.1\|2008324_2008546_-	DUF3269 family protein	A0A2H4PQI9	Staphylococcus_phage	1.4e-34	97.3
WP_001024405.1\|2008549_2008765_-	hypothetical protein	Q4ZBU5	Staphylococcus_virus	4.8e-35	100.0
WP_001106166.1\|2008761_2010003_-	AAA family ATPase	M9NSS7	Staphylococcus_phage	2.6e-229	100.0
WP_001132236.1\|2009999_2010356_-	hypothetical protein	M9NS37	Staphylococcus_phage	2.4e-63	99.2
WP_001037657.1\|2010355_2011111_-	DnaD domain protein	C8CGZ1	Staphylococcus_phage	3.8e-143	100.0
WP_001121810.1\|2011103_2011778_-	hypothetical protein	C8CGZ0	Staphylococcus_phage	4.7e-129	100.0
WP_000934775.1\|2011791_2012220_-	single-stranded DNA-binding protein	B2ZYV4	Staphylococcus_phage	6.8e-57	91.5
WP_000840497.1\|2012219_2012873_-	ERF family protein	A0A1J0MFT8	Staphylococcus_phage	2.6e-68	61.4
WP_001004335.1\|2012873_2013410_-	host-nuclease inhibitor Gam family protein	A0A0F6N4M6	Staphylococcus_phage	2.5e-80	99.4
WP_000291101.1\|2013422_2013683_-	DUF1108 family protein	A0A1W6JQ03	Staphylococcus_phage	9.3e-41	95.3
WP_000048124.1\|2013779_2013941_-	DUF1270 family protein	C7F7L3	Staphylococcus_phage	1.9e-20	100.0
WP_000977378.1\|2013933_2014155_-	hypothetical protein	E0Y3P2	Staphylococcus_virus	1.5e-31	100.0
WP_001791098.1\|2014226_2014892_+	hypothetical protein	Q9G033	Staphylococcus_virus	5.0e-115	97.7
WP_001148585.1\|2015005_2015746_-	phage antirepressor KilAC domain-containing protein	A0A0N7E0R7	Staphylococcus_phage	6.3e-135	100.0
WP_000394410.1\|2015805_2016288_+	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
WP_000438352.1\|2016388_2016568_-	hypothetical protein	A0A0N9BAV3	Staphylococcus_phage	1.7e-25	100.0
WP_001002759.1\|2016583_2017348_-	phage antirepressor Ant	R4IFK0	Staphylococcus_phage	2.7e-141	99.6
WP_000108122.1\|2017347_2017542_-	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	1.1e-25	100.0
WP_001055143.1\|2017804_2018137_+	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	4.1e-57	100.0
WP_000775187.1\|2018153_2018828_+	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	4.9e-126	100.0
WP_000661437.1\|2018855_2019581_+	PH domain-containing protein	A0A0F6N4L7	Staphylococcus_phage	9.9e-125	100.0
WP_000440838.1\|2019612_2020317_+	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	4.6e-127	100.0
WP_001145732.1\|2020513_2021560_+\|integrase	site-specific integrase	A0A0H3U2V9	Staphylococcus_phage	4.2e-201	100.0
2025024:2025041	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2056970 : 2161180

127

Staphylococcus_phage(91.36%)

terminase,integrase,portal,transposase,tail,capsid,holin,head,protease

attL 2134773:2134791|attR 2159164:2159182

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000827748.1\|2056970_2058137_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434933.1\|2058167_2058494_+	staphostatin A	NA	NA	NA	NA
WP_000669862.1\|2058785_2058959_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2058939_2059542_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040873.1\|2059812_2060634_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.8e-69	52.7
WP_000284431.1\|2060626_2062096_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	4.5e-108	45.1
WP_000897635.1\|2062279_2063356_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177817.1\|2063375_2064170_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2064241_2064349_+	hypothetical protein	NA	NA	NA	NA
WP_000323161.1\|2064359_2065922_-	SLC13 family permease	NA	NA	NA	NA
WP_000275730.1\|2066126_2067224_-	pectate lyase	U5PWM6	Bacillus_phage	1.9e-47	34.6
WP_000149686.1\|2067595_2068156_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2068208_2069138_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2069332_2069506_-	hypothetical protein	NA	NA	NA	NA
WP_001021214.1\|2069557_2070937_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181325.1\|2071056_2072085_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2072354_2072756_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2073328_2073502_-	hypothetical protein	NA	NA	NA	NA
WP_001188077.1\|2073952_2074993_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713060.1\|2075049_2075892_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2075888_2076446_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2076505_2077030_-	membrane protein	NA	NA	NA	NA
WP_001106019.1\|2077207_2077882_-\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	8.1e-129	100.0
WP_000611512.1\|2077947_2078202_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861038.1\|2078213_2078969_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000920041.1\|2079159_2079651_+	staphylokinase	A7TWR8	Staphylococcus_phage	8.0e-86	100.0
WP_000702262.1\|2081148_2081499_+	complement inhibitor SCIN-A	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
WP_001791826.1\|2081551_2081812_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000669789.1\|2082122_2082302_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001549158.1\|2083259_2085014_+	extracellular adherence protein Eap/Map	NA	NA	NA	NA
WP_001068542.1\|2085638_2086925_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000990056.1\|2087124_2087223_+	hypothetical protein	NA	NA	NA	NA
WP_000681968.1\|2087465_2087642_+	hypothetical protein	NA	NA	NA	NA
WP_000691584.1\|2087905_2088286_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000991302.1\|2088282_2089179_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000645727.1\|2089179_2089860_+	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000763048.1\|2089856_2090729_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_001221651.1\|2090728_2091469_+	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000182842.1\|2091534_2092098_-	thioredoxin family protein	NA	NA	NA	NA
WP_001106022.1\|2092164_2092839_+\|transposase	IS6-like element IS257 family transposase	A0A0N9SKD3	Staphylococcus_phage	6.2e-129	100.0
WP_000175735.1\|2093302_2093788_-	trimethoprim-resistant dihydrofolate reductase DfrC	A0A0N9S8H6	Staphylococcus_phage	1.1e-90	100.0
WP_000282655.1\|2093829_2094786_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.1e-190	100.0
WP_001106019.1\|2094899_2095574_+\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	8.1e-129	100.0
WP_001791613.1\|2096437_2096530_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_000403117.1\|2096672_2097905_-	hypothetical protein	NA	NA	NA	NA
WP_000262986.1\|2099443_2099701_+	hypothetical protein	NA	NA	NA	NA
WP_000527036.1\|2099873_2100353_+	hypothetical protein	NA	NA	NA	NA
WP_002484480.1\|2100358_2100997_+	hypothetical protein	NA	NA	NA	NA
WP_000850931.1\|2101102_2101621_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_000748213.1\|2101698_2102565_+	hypothetical protein	NA	NA	NA	NA
WP_000274669.1\|2102678_2102933_+	hypothetical protein	NA	NA	NA	NA
WP_001076470.1\|2103258_2103870_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000842630.1\|2104880_2105681_+	ABC transporter permease	NA	NA	NA	NA
WP_000926712.1\|2105777_2106056_+	hypothetical protein	NA	NA	NA	NA
WP_002484873.1\|2106271_2106424_+	hypothetical protein	NA	NA	NA	NA
WP_002484872.1\|2106410_2106569_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_002484560.1\|2108286_2109024_+	DUF536 domain-containing protein	NA	NA	NA	NA
WP_001807343.1\|2109160_2109283_-	HAD hydrolase family protein	NA	NA	NA	NA
WP_001077893.1\|2109358_2109919_-	hypothetical protein	NA	NA	NA	NA
WP_000195429.1\|2110120_2111293_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000393259.1\|2111349_2111742_+	GNAT family N-acetyltransferase	A0A0N7GFH7	Staphylococcus_phage	6.9e-72	100.0
WP_001028144.1\|2111742_2113182_+	aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.8e-285	100.0
WP_000195429.1\|2113311_2114484_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000622776.1\|2114697_2116242_-	quaternary ammonium compound efflux MFS transporter QacA	NA	NA	NA	NA
WP_001807342.1\|2116419_2116986_+	multidrug-binding transcriptional regulator QacR	NA	NA	NA	NA
WP_000797248.1\|2117118_2117304_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001049146.1\|2117308_2117647_-	hypothetical protein	NA	NA	NA	NA
WP_000583528.1\|2117892_2118501_-	recombinase family protein	M9Q1K0	Clostridium_phage	3.6e-19	34.4
WP_000495112.1\|2118783_2119047_+	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_001106019.1\|2119076_2119751_+\|transposase	IS6-like element IS257 family transposase	A0A0N9RU54	Staphylococcus_phage	8.1e-129	100.0
WP_072482930.1\|2120019_2120196_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	3.8e-22	96.6
WP_000750412.1\|2120304_2121078_-	staphylococcal enterotoxin type A	A0A1X9H080	Staphylococcus_phage	1.1e-145	100.0
WP_000340977.1\|2121450_2121825_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001262621.1\|2121880_2122168_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
WP_001000058.1\|2122213_2122366_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
WP_000582173.1\|2122358_2126141_-	hypothetical protein	A0A1X9H096	Staphylococcus_phage	0.0e+00	99.7
WP_000567408.1\|2126156_2127641_-\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
WP_001096355.1\|2132411_2132762_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_072050172.1\|2132811_2133036_-	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	8.8e-32	98.6
WP_000268741.1\|2133077_2133722_-\|tail	phage tail protein	W5R9H4	Staphylococcus_phage	6.5e-120	100.0
WP_000565498.1\|2133722_2134130_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114225.1\|2134126_2134531_-	HK97 gp10 family phage protein	A0A2I6PDJ6	Staphylococcus_phage	4.3e-69	100.0
WP_000755150.1\|2134527_2134890_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2134773:2134791	attL	NA	NA	NA	NA
WP_000150936.1\|2134873_2135158_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|2135147_2135432_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154555.1\|2135451_2136597_-\|capsid	phage major capsid protein	A0A1X9H072	Staphylococcus_phage	5.6e-215	100.0
WP_000861914.1\|2136620_2137358_-\|protease	Clp protease ClpP	C8CH20	Staphylococcus_phage	2.3e-129	100.0
WP_000025274.1\|2137341_2138529_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1\|2138544_2140206_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|2140202_2140547_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988336.1\|2140677_2140977_-	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
WP_000590126.1\|2141208_2141625_-	hypothetical protein	A0A1X9H0U8	Staphylococcus_phage	2.9e-76	100.0
WP_000265039.1\|2141652_2141853_-	DUF1514 family protein	R9QT57	Staphylococcus_phage	1.4e-28	98.5
WP_000595265.1\|2141852_2142002_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000195820.1\|2141998_2142205_-	DUF1381 domain-containing protein	A0A1X9H0C2	Staphylococcus_phage	1.3e-21	100.0
WP_001066444.1\|2142241_2142778_-	dUTP diphosphatase	A0A1X9H0S5	Staphylococcus_phage	1.4e-96	100.0
WP_000197967.1\|2142770_2143181_-	hypothetical protein	C8CH13	Staphylococcus_phage	2.3e-70	100.0
WP_001105598.1\|2143177_2143687_-	hypothetical protein	A0A1X9H0D4	Staphylococcus_phage	3.2e-93	100.0
WP_000982711.1\|2143683_2144133_-	hypothetical protein	A0A2I6PDH2	Staphylococcus_phage	2.1e-80	99.3
WP_000131366.1\|2144197_2144440_-	hypothetical protein	A0EWX8	Staphylococcus_phage	3.9e-41	100.0
WP_000101274.1\|2144443_2144812_-	hypothetical protein	W5RAK8	Staphylococcus_phage	8.2e-51	100.0
WP_000401964.1\|2144824_2145229_-	RusA family crossover junction endodeoxyribonuclease	A0A0E3XBN4	Staphylococcus_phage	1.4e-72	100.0
WP_000338528.1\|2145237_2145456_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_000148301.1\|2145462_2146347_-	DnaD domain protein	S4V6D4	Staphylococcus_phage	3.1e-136	95.9
WP_000934770.1\|2146376_2146847_-	single-stranded DNA-binding protein	A0A0E3T9H6	Staphylococcus_phage	4.8e-80	99.4
WP_071621397.1\|2146847_2147465_-	MBL fold metallo-hydrolase	S4SWA4	Staphylococcus_phage	9.1e-87	100.0
WP_000138481.1\|2147545_2148466_-	recombinase RecT	A0A1V0E5D7	Staphylococcus_phage	1.0e-166	100.0
WP_000700565.1\|2148467_2150411_-	AAA family ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	99.1
WP_001205732.1\|2150419_2150683_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291489.1\|2150691_2150952_-	DUF1108 family protein	A0A1W6JQ03	Staphylococcus_phage	7.6e-43	100.0
WP_000066020.1\|2151044_2151206_-	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
WP_001120197.1\|2151202_2151523_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000275058.1\|2151581_2152214_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
WP_000939496.1\|2152228_2152369_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
WP_000388066.1\|2152399_2152594_-	hypothetical protein	A0A1X9H0A2	Staphylococcus_phage	1.5e-19	100.0
WP_001148618.1\|2152610_2153363_-	phage antirepressor KilAC domain-containing protein	A0A1X9H0A0	Staphylococcus_phage	8.7e-140	100.0
WP_000351243.1\|2153419_2153959_+	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
WP_000435341.1\|2153982_2154243_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000548578.1\|2154255_2154495_-	helix-turn-helix transcriptional regulator	G4KNM9	Staphylococcus_phage	2.3e-38	100.0
WP_000094093.1\|2154665_2155373_+	helix-turn-helix transcriptional regulator	G4KNM8	Staphylococcus_phage	7.7e-130	100.0
WP_001049399.1\|2155384_2155540_+	hypothetical protein	A0A2I6PDR9	Staphylococcus_phage	6.3e-21	100.0
WP_001089804.1\|2155526_2155712_+	hypothetical protein	A0A2I6PDS4	Staphylococcus_phage	2.3e-25	100.0
WP_000705238.1\|2155911_2156079_+	hypothetical protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
WP_000391618.1\|2156218_2156758_+	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	9.0e-14	33.1
WP_000857198.1\|2156930_2157968_+\|integrase	site-specific integrase	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
WP_000595323.1\|2159086_2160103_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	1.1e-25	29.0
2159164:2159182	attR	NA	NA	NA	NA
WP_000791407.1\|2160124_2161180_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3

Anti-CRISPR protein detection

Acr_ID: NC_017341.1|WP_000809857.1|1912177_1912363_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_017341.1|WP_000809857.1|1912177_1912363_-|hypothetical-protein

1912177_1912363_-

61 aa aa

1834802-1913682

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017341_11	Orphan	11.2\|2421197\|36\|NC_017341\|CRT	2421197-2421232	36	1853686-1853651	1

1. spacer 11.2|2421197|36|NC_017341|CRT matches to NC_017341 position: 1853686-1853651, mismatch: 1

tgcattgtctgtagaatttctttttgaaattctcta	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaattctcta	Protospacer
************************.***********

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017341

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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