CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018078	Mycobacterium tuberculosis KZN 605, complete sequence	14 crisprs	csa3,c2c9_V-U4,cas6,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csm6,cas1,cas2,DEDDh,cas4,WYL,DinG,cas3	10	29	2	0

1. NC_018078

CRISPR-Cas detection and classification

Crispr_ID: NC_018078_1

• CRISPR_ID: NC_018078_1
• CRISPR_location: 334757-334868
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_018078_1

Consensus_repeat	Method
CCGCCGTTGCCGCCGTTGCCGATCA	PILER-CR

spacers of NC_018078_1

>1.1|334782|20|NC_018078|PILER-CR
GCACGCCGTTACCGCCCGCT
>1.2|334827|17|NC_018078|PILER-CR
CGCTGGCGCCGCCGTCA

CRISPR arrays and Neighbor proteins around NC_018078_1

CRISPR arrays

The CRISPR arrays of NC_018078_1

>merge|NC_018078|1|334757-334868|PILER-CR
CCGCCGTTGCCGCCGTTGCCGATCTGCACGCCGTTACCGCCCGCTCCGCCGTTGCCGCCGGTGCCGGTCACGCTGGCGCCGCCGTCACCGCCGTTGCCGCCGTTGCCGATCA

>NC_018078|1|1|334757-334868|PILER-CR
CCGCCGTTGCCGCCGTTGCCGATCT	GCACGCCGTTACCGCCCGCT
CCGCCGTTGCCGCCGGTGCCGGTCA	CGCTGGCGCCGCCGTCA
CCGCCGTTGCCGCCGTTGCCGATCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003401503.1|354390_354684_+|type-VII-secretion-system-protein-EsxG	unknown	unknown	gnl|CDD|274862
NC_018078.1|WP_009938203.1|326204_328400_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_018078.1|WP_003401397.1|329643_330264_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_018078.1|WP_003401399.1|330360_330942_+|VOC-family-protein	unknown	unknown	gnl|CDD|366361
NC_018078.1|WP_003401485.1|352489_352798_+|type-VII-secretion-system-ESX-3-target-PE5	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003898392.1|344995_346891_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3	unknown	unknown	gnl|CDD|188437
NC_018078.1|WP_003401478.1|348500_352493_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3	unknown	unknown	gnl|CDD|274858
NC_018078.1|WP_003401394.1|328513_329647_-|hypothetical-protein	unknown	unknown	gnl|CDD|378820
NC_018078.1|WP_003899884.1|324505_326188_+|acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236097
NC_018078.1|WP_003401386.1|323276_324470_-|DNA-polymerase-domain-containing-protein	unknown	unknown	gnl|CDD|225823
NC_018078.1|WP_009938204.1|332646_333075_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350245
NC_018078.1|WP_003401404.1|331686_332607_+|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|226188
NC_018078.1|WP_003899886.1|330871_331597_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_018078.1|WP_010950374.1|342229_343840_+|PPE-family-protein	unknown	unknown	gnl|CDD|227938
NC_018078.1|WP_014585492.1|339425_341939_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_011961607.1|333098_333281_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003401488.1|352800_354342_+|type-VII-secretion-system-ESX-3-target-PPE4	unknown	unknown	gnl|CDD|227938
NC_018078.1|WP_003401448.1|343863_344772_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225852
NC_018078.1|WP_003401472.1|346887_348504_+|type-VII-secretion-system-ESX-3-subunit-EccB3	unknown	unknown	gnl|CDD|368288
NC_018078.1|WP_031655831.1|336437_339176_-|PE-family-protein	unknown	unknown	gnl|CDD|376422

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003401503.1|354390_354684_+|type-VII-secretion-system-protein-EsxG	gnl|CDD|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	0.00514324
NC_018078.1|WP_009938203.1|326204_328400_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.73878e-158
NC_018078.1|WP_031655831.1|336437_339176_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.97562e-34
NC_018078.1|WP_003401397.1|329643_330264_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.87158e-12
NC_018078.1|WP_003401399.1|330360_330942_+|VOC-family-protein	gnl|CDD|366361	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	5.1808e-20
NC_018078.1|WP_003401485.1|352489_352798_+|type-VII-secretion-system-ESX-3-target-PE5	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	7.41358e-11
NC_018078.1|WP_003898392.1|344995_346891_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3	gnl|CDD|188437	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA. This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_018078.1|WP_003401478.1|348500_352493_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3	gnl|CDD|274858	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa. This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_018078.1|WP_003401394.1|328513_329647_-|hypothetical-protein	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	0.00172554
NC_018078.1|WP_003899884.1|324505_326188_+|acyl-CoA-synthetase	gnl|CDD|236097	PRK07788, PRK07788, acyl-CoA synthetase; Validated.	0
NC_018078.1|WP_003401386.1|323276_324470_-|DNA-polymerase-domain-containing-protein	gnl|CDD|225823	COG3285, COG3285, Predicted eukaryotic-type DNA primase [DNA replication, recombination, and repair].	2.78761e-127
NC_018078.1|WP_009938204.1|332646_333075_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350245	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC25, VapC29, VapC33, VapC37, and VapC39 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	3.90741e-60
NC_018078.1|WP_003401404.1|331686_332607_+|DUF2236-domain-containing-protein	gnl|CDD|226188	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown].	2.89836e-118
NC_018078.1|WP_003899886.1|330871_331597_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.66172e-07
NC_018078.1|WP_010950374.1|342229_343840_+|PPE-family-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	1.45056e-73
NC_018078.1|WP_003401472.1|346887_348504_+|type-VII-secretion-system-ESX-3-subunit-EccB3	gnl|CDD|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	0
NC_018078.1|WP_003401488.1|352800_354342_+|type-VII-secretion-system-ESX-3-target-PPE4	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	1.09345e-59
NC_018078.1|WP_003401448.1|343863_344772_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	1.10201e-94
NC_018078.1|WP_014585492.1|339425_341939_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.14713e-32

Protein sequences

>NC_018078.1|WP_011961607.1|333098_333281_-|hypothetical-protein
MGAVIEDALRRELAAARTGGARPTVPVFDAGTGPRPGIDLTSNTVLSEVLDEGLELNSRK
>NC_018078.1|WP_009938204.1|332646_333075_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MFLIDVNVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLTTNRRIFEIPSPRADAFAFVEAVTAQPHHLPTSPGPRHLVLLRKLCDEADASGDLIPDAVLGAIAVEHHCAVVSLDRDFARFASVRHIRPPI
>NC_018078.1|WP_003401404.1|331686_332607_+|DUF2236-domain-containing-protein
MAISLVAHQPIPHVERPMADPPRLQLARRRRSAAGPGGNEDSLMGVALLAGPANVIMELAMPGVGYGVLESRVESGRLDRHPIKRARTTFTYVAVAVAGSDDQKAAFRRAVNKVHAQVYSTPESPVSYHAFDPELQLWVAACLYKGGVDVYRTFVGEMDDEEADHHYRAGMAMGTTLQVPPQMWPPDRAAFDRYWRQSLDRVHIDDVVRDYLYPIVALRIRGIALPGPLRRLSEGIALLITTGFLPQRFRDEMRLPWDATKQRRFDALMAVLRTVNRLMPRFVREFPFNLMLWDLDRRMRRGRPLV
>NC_018078.1|WP_003899886.1|330871_331597_-|TetR/AcrR-family-transcriptional-regulator
MTRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
>NC_018078.1|WP_003401399.1|330360_330942_+|VOC-family-protein
MIKPHNTNTEFELGGINHVALVCSDMARTVDFYSNILGMPLIKALDLPGGQGQHFFFDAGNGDCVAFFWFADAPDRVPGLSSPVAIPGIGDITSAVSTMNHLAFHVPAERFDAYRQRLKDKGVRVGPVLNHDDSETQVSAVVHPGVYVRSFYFQDPDGITLEFACWTKEFTTSDAQAVPKTAADRRPPVAADR
>NC_018078.1|WP_003401397.1|329643_330264_-|TetR/AcrR-family-transcriptional-regulator
MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN
>NC_018078.1|WP_003401394.1|328513_329647_-|hypothetical-protein
MTGRAATPGVIREFVGLPSRTAGRAAAGGHPCQGLYHHSVGRKPKVALIAAHYQIDFSEHYLAEYMAIRGIGFLGWNTRFRGFESSFLLDHALVDIGVGVRWLREVQGVETVVLLGNSGGGSLMAAYQSQAVDPNVTPLDGMRPAAGVTELPAADAYVAAAAHPGRPDVLTAWMDAAVIDENDPVATDPELDLFDERNGPPYSPEFISRYRSAQVKRNHTITDWAESELKRVRAAGFSDRPFSVMRTWADPRMVDPSIEPTKRRPNQCYAGTPVKANRSAHGIAAACTLRGWLGMWSLRVAQTRAAPHLARITCPALVLNAEADTGIFPSDAQQIYDGLASSDKTQVSIDTDHYFTTPGARSEQADTIAKWIAKRWR
>NC_018078.1|WP_009938203.1|326204_328400_-|acyl-CoA-dehydrogenase
MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGYGAVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIESRDEWVVLRNDQLEIEAVKSLDPLRPIAHIRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIREQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFTWEHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGWVLPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSDLASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYLDDVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLLNLRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNIIAERLLGLPRDP
>NC_018078.1|WP_003899884.1|324505_326188_+|acyl-CoA-synthetase
MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNYAALAADIRKWGEVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAVANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQIKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSDETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNTPPTLAPIGGILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPALVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQLGAELATRALGDLGPVIYNMYGSTEVAFATIAGPKDLQFNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGGKQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVEDLISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLDEDTIKQYVRDHLARYKVPREVIFLDELPRNPTGKVLKRELRKL
>NC_018078.1|WP_003401386.1|323276_324470_-|DNA-polymerase-domain-containing-protein
MSRMAAPVSLDVHGRQVIVTHPGRVVFPAHNDRKGYTKFDLVRYYLAVAEGAMRGVAGRPMILKRFVKGISAEAVFQKRAPANRPDWVDVAELHYASGRSAAEAVIHDAAGLAWVINLGCVDLNPHPVLAGDLDHPDELRVDLDPMPGVAWQRVVEVALVVREVLEDYGLTAWPKTSGSRGFHVYARIAPCWSFPQVRLAAQTVAREVERRLPDAATSRWWKEEREGVFVDFNQNAKDRTVASAYSVRATPDARVSTPLHWEEVPGCDPAVFTMATVPSRLADIGDPWAGMDDAVGRLDRLLMLAEELGPPQKAQSAKPLIEIARAKTRAEAMAALDIWRDRYPGAAALLRPADVLVDGMRGPSSIWYRIRINLQHVPADQRPPQEELIADYSPWPR
>NC_018078.1|WP_031655831.1|336437_339176_-|PE-family-protein
MSFVIAAPEVIAAAATDLASLGSSISAANAAAAANTTALMAAGADEVSTAIAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAAAVSPLLDPINEFFLANTGRPLIGNGANGAPGTGANGGDGGWLIGNGGAGGSGAAGVNGGAGGNGGAGGLIGNGGAGGAGGVASSGIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGGAGGAGGAGGNAGLLFGAAGVGGAGGFTNGSALGGAGGAGGAGGLFATGGVGGSGGAGSSGGAGGAGGAGGLFGAGGTGGHGGFADSSFGGVGGAGGAGGLFGAGGEGGSGGHSLVAGGDGGAGGNAGMLALGAAGGAGGIGGDGGTLTAGGIGGAGGAGGNAGLLFGSGGSGGAGGFGFADGGQGGPGGNAGTVFGSGGAGGNGGVGQGFAGGIGGAGGTPGLIGNGGNGGNGGASAVTGGNGGIGGTGVLIGNGGNGGSGGIGAGKAGVGGVSGLLLGLDGFNAPASTSPLHTLQQNVLNVVNEPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGSGATGTNGGDGGDGGAGGIFFGTGGTGGAGGVGTTGTGGDGGAGGAAFLMGSGGNGGSGGAGLTAGGDGGDGGNAGSFFGAAGTGGAGASTKAGGTGGTGGNGGLFANGGAGGSGGLGGDAGTGGAGGNGGLFGAGGTGGAGGSLGPGAGGAGGNGGLFGAGGTGGAGGSLGPGAGGAGGNGGLFGAGGTGGSGGAGGNAGLFSLGASGGAGGSGGSSLTDGGGIGGVGGAGGLLFGYGGAGGAGGYSNIGAGGAGGAGGNAGMLSGSGGSGGTGGASGAAKGGVGGNGGTAGVFGNGGDGGAGGFGAGTGGNGGVGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLLIGENGLNGLP
>NC_018078.1|WP_014585492.1|339425_341939_-|PE-family-protein
MSFVIAAPEVIAAAATDLASLESSISAANAAAAANTTALLAAGADEVSTAVAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAAATSPLLAPINEFFLANTGRPLIGNGTNGAPGTGANGGDGGWLIGNGGAGGSGAAGVNGGAGGNGGAGGLIGNGGAGGAGGRASTGTGGAGGAGGAAGMLFGAAGVGGPGGFAAAFGATGGAGGAGGNGGLFADGGVGGAGGATDAGTGGAGGSGGNGGLFGAGGTGGPGGFGIFGGGAGGDGGSGGLFGAGGTGGSGGTSIINVGGNGGAGGDAGMLSLGAAGGAGGSGGSSPDGGGGAGGIGGDGGTLFGSGGAGGVGGLGFDAGGAGGAGGKAGLLSGAGGAGGAGGGSFAGAGGTGGAGGAPGLVGNAGNGGNGGASANGAGAAGGAGGSGVLIGNGGNGGSGGTGAPAGTAGAGGLGGQLLGRDGFNAPASTPLHTLQQQILNAINEPTQALTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGHGATGADGGDGGSGGAGGILSGIGGTGGSGGIGTTGQGGTGGTGGAALLIGSGGTGGSGGFGLDTGGAGGRGGDAGLFLGAAGTGGQAALSQNFIGAGGTAGAGGTGGLFANGGAGGAGGFGANGGTGGNGLLFGAGGTGGAGTLGADGGAGGHGGLFGAGGTGGAGGSSGGTFGGNGGSGGNAGLLALGASGGAGGSGGSALNVGGTGGVGGNGGSGGSLFGFGGAGGTGGSSGIGSSGGTGGDGGTAGVFGNGGDGGAGGFGAGTGGNGGVGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLIIGENGLNGL
>NC_018078.1|WP_010950374.1|342229_343840_+|PPE-family-protein
MTLWMASPPEVHSALLSSGPGPGSVLSAAGVWSSLSAEYAAVADELIGLLGAVQTGAWQGPSAAAYVAAHAPYLAWLMRASETSAEAAARHETVAAAYTTAVAAMPTLVELAANHTLHGVLVATNFFGINTIPIALNEADYARMWTQAASTMATYQAVAEAAVASAPQTTPAPPILAAEAADDDHDHDHDHGGEPTPLDYLVAEILRIISGGRLIWDPAEGTMNGIPFEDYTDAAQPIWWVVRAIEFSKDFETFVQELFVNPVEAFQFYFELLLFDYPTHIVQIVEALSQSPQLLAVALGSVISNLGAVTGFAGLSGLAGMQPAAIPALAPVAAAPPTLPAVAMAPTMAAPGAAVASAAAPASAPAASTVASATPAPPPAPGAAGFGYPYAIAPPGIGFGSGMSASASAQRKAPQPDSAAAAAAAAAVRDQARARRRRRVTRRGYGDEFMDMNIDVDPDWGPPPGEDPVTSTVASDRGAGHLGFAGTARREAVADAAGMTTLAGDDFGDGPTTPMVPGSWDPDRDAPGSAEPGDRG
>NC_018078.1|WP_003401448.1|343863_344772_+|class-I-SAM-dependent-methyltransferase
MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRAVGGSWADVLDGKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGPDEYAAKVEEERAAIAEGAEEHPFFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAVGRPVPGPESEAGPMFARNTLVSAARV
>NC_018078.1|WP_003898392.1|344995_346891_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3
MAGVGEGDSGGVERDDIGMVAASPVASRVNGKVDADVVGRFATCCRALGIAVYQRKRPPDLAAARSGFAALTRVAHDQCDAWTGLAAAGDQSIGVLEAASRTATTAGVLQRQVELADNALGFLYDTGLYLRFRATGPDDFHLAYAAALASTGGPEEFAKANHVVSGITERRAGWRAARWLAVVINYRAERWSDVVKLLTPMVNDPDLDEAFSHAAKITLGTALARLGMFAPALSYLEEPDGPVAVAAVDGALAKALVLRAHVDEESASEVLQDLYAAHPENEQVEQALSDTSFGIVTTTAGRIEARTDPWDPATEPGAEDFVDPAAHERKAALLHEAELQLAEFIGLDEVKRQVSRLKSSVAMELVRKQRGLTVAQRTHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGLRSRFTRNIDFPSYTSHELVEIAHKMAEQRDSVFEQSALHDLEALFAKLAAESTPDTNGISRRSLDIAGNGRFVRNIVERSEEEREFRLDHSEHAGSGEFSDEELMTITADDVGRSVEPLLRGLGLSVRA
>NC_018078.1|WP_003401472.1|346887_348504_+|type-VII-secretion-system-ESX-3-subunit-EccB3
MTNQQHDHDFDHDRRSFASRTPVNNNPDKVVYRRGFVTRHQVTGWRFVMRRIAAGIALHDTRMLVDPLRTQSRAVLMGVLIVITGLIGSFVFSLIRPNGQAGSNAVLADRSTAALYVRVGEQLHPVLNLTSARLIVGRPVSPTTVKSTELDQFPRGNLIGIPGAPERMVQNTSTDANWTVCDGLNAPSRGGADGVGVTVIAGPLEDTGARAAALGPGQAVLVDSGAGTWLLWDGKRSPIDLADHAVTSGLGLGADVPAPRIIASGLFNAIPEAPPLTAPIIPDAGNPASFGVPAPIGAVVSSYALKDSGKTISDTVQYYAVLPDGLQQISPVLAAILRNNNSYGLQQPPRLGADEVAKLPVSRVLDTRRYPSEPVSLVDVTRDPVTCAYWSKPVGAATSSLTLLAGSALPVPDAVHTVELVGAGNGGVATRVALAAGTGYFTQTVGGGPDAPGAGSLFWVSDTGVRYGIDNEPQGVAGGGKAVEALGLNPPPVPIPWSVLSLFVPGPTLSRADALLAHDTLVPDSRPARPVSAEGGYR
>NC_018078.1|WP_003401478.1|348500_352493_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3
MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGILIVGMIVALVATGMRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDAERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERDPHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRSIGDVPTGIDLTKVSRITVLGERAQVRAVLRAWIAQAVTWHDPTVLGVALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGPVLADRPAFTGQPTDALRHLLIVVDDPDYDLGASPLAVGRAGVTVVHCSASAPHREQYSDPEKPILRVAHGAIERWQTGGWQPYIDAADQFSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVPALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNMAEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIAAGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILFASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHKGVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAVEPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETIPLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGGPKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVASALEPERIRRTFGELEQLLLSRQQREVFRDRGANGSTPDDGFGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITTPSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVGALRRPADAVPHDQPGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAPHAVGELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTLLRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRWTFAGHTHYLIIDDVDQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPLVDAAAVSGETQQKGSQS
>NC_018078.1|WP_003401485.1|352489_352798_+|type-VII-secretion-system-ESX-3-target-PE5
MTLRVVPEGLAAASAAVEALTARLAAAHASAAPVITAVVPPAADPVSLQTAAGFSAQGVEHAVVTAEGVEELGRAGVGVGESGASYLAGDAAAAATYGVVGG
>NC_018078.1|WP_003401488.1|352800_354342_+|type-VII-secretion-system-ESX-3-target-PPE4
MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAASTVGAVNPWQWLLALLQQLWNAYTGFYGWMLQLIWQFLQDPIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSSPFLLPAGLGLGLAAIAFLPIVLAPAVIPPASTPLAAAAVAAGSVWPAVSMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATASFAYAVGGSGDWGPSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRSELRDYGDEFLDMDSDSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRAVGLTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHDSK
>NC_018078.1|WP_003401503.1|354390_354684_+|type-VII-secretion-system-protein-EsxG
MSLLDAHIPQLVASQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQGESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAAGTYVAADAAAASTYTGF

Crispr_ID: NC_018078_2

• CRISPR_ID: NC_018078_2
• CRISPR_location: 340970-341192
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_018078_2

Consensus_repeat	Method
ATCCGCCGCTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCC	PILER-CR

spacers of NC_018078_2

>2.1|341013|67|NC_018078|PILER-CR
GCACCGAGGCTGAGCATGCCGGCGTCGCCGCCGGCCCCACCGTTCCCGCCGACGTTGATTATGCTCG
>2.2|341123|41|NC_018078|PILER-CR
AGAGCCGCCATCCCCGCCGGCGCCGCCGCCAAAGATGCCGA

CRISPR arrays and Neighbor proteins around NC_018078_2

CRISPR arrays

The CRISPR arrays of NC_018078_2

>merge|NC_018078|2|340970-341192|PILER-CR
ATCCGCCGCTGCCGCCGGCGCCGCCGGCGGCACCGAGGCTGAGCATGCCGGCGTCGCCGCCGGCCCCACCGTTCCCGCCGACGTTGATTATGCTCGTCCCGCCACTACCGCCGGTGCCGCCGGCGCCGAACAGCCCGCCAGAGCCGCCATCCCCGCCGGCGCCGCCGCCAAAGATGCCGAATCCGCCGGGCCCACCGGTGCCGCCGGCGCCGAACAGCCCGCC

>NC_018078|2|2|340970-341192|PILER-CR
ATCCGCCGCTGCCGCCGGCGCCGCCGGCGGCACCGAGGCTGAG	CATGCCGGCGTCGCCGCCGGCCCCACCGTTCCCGCCGACGTTGATTATGCTCGTCCCGCCACTACCG
CCGGTGCCGCCGGCGCCGAACAGCCCGCCAGAGCCGCCATCCC	CGCCGGCGCCGCCGCCAAAGATGCCGAATCCGCCGGGCCCA
CCGGTGCCGCCGGCGCCGAACAGCCCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003401503.1|354390_354684_+|type-VII-secretion-system-protein-EsxG	unknown	unknown	gnl|CDD|274862
NC_018078.1|WP_009938203.1|326204_328400_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_018078.1|WP_031655831.1|336437_339176_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003401399.1|330360_330942_+|VOC-family-protein	unknown	unknown	gnl|CDD|366361
NC_018078.1|WP_003401485.1|352489_352798_+|type-VII-secretion-system-ESX-3-target-PE5	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003898392.1|344995_346891_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3	unknown	unknown	gnl|CDD|188437
NC_018078.1|WP_003401478.1|348500_352493_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3	unknown	unknown	gnl|CDD|274858
NC_018078.1|WP_003401394.1|328513_329647_-|hypothetical-protein	unknown	unknown	gnl|CDD|378820
NC_018078.1|WP_014830004.1|333375_336174_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003401521.1|355014_355902_+|type-VII-secretion-system-ESX-3-associated-protein-EspG3	unknown	unknown	gnl|CDD|379414
NC_018078.1|WP_003401488.1|352800_354342_+|type-VII-secretion-system-ESX-3-target-PPE4	unknown	unknown	gnl|CDD|227938
NC_018078.1|WP_009938204.1|332646_333075_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350245
NC_018078.1|WP_003401514.1|354713_355004_+|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl|CDD|227179
NC_018078.1|WP_003401404.1|331686_332607_+|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|226188
NC_018078.1|WP_003899886.1|330871_331597_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_018078.1|WP_010950374.1|342229_343840_+|PPE-family-protein	unknown	unknown	gnl|CDD|227938
NC_018078.1|WP_011961607.1|333098_333281_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003401448.1|343863_344772_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225852
NC_018078.1|WP_003401472.1|346887_348504_+|type-VII-secretion-system-ESX-3-subunit-EccB3	unknown	unknown	gnl|CDD|368288
NC_018078.1|WP_003401397.1|329643_330264_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003401503.1|354390_354684_+|type-VII-secretion-system-protein-EsxG	gnl|CDD|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	0.00514324
NC_018078.1|WP_009938203.1|326204_328400_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	1.73878e-158
NC_018078.1|WP_031655831.1|336437_339176_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	4.97562e-34
NC_018078.1|WP_003401399.1|330360_330942_+|VOC-family-protein	gnl|CDD|366361	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	5.1808e-20
NC_018078.1|WP_003401485.1|352489_352798_+|type-VII-secretion-system-ESX-3-target-PE5	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	7.41358e-11
NC_018078.1|WP_003898392.1|344995_346891_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3	gnl|CDD|188437	TIGR03922, T7SS_EccA, type VII secretion AAA-ATPase EccA. This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_018078.1|WP_003401478.1|348500_352493_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3	gnl|CDD|274858	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa. This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_018078.1|WP_003401394.1|328513_329647_-|hypothetical-protein	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	0.00172554
NC_018078.1|WP_014830004.1|333375_336174_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.01992e-31
NC_018078.1|WP_003401521.1|355014_355902_+|type-VII-secretion-system-ESX-3-associated-protein-EspG3	gnl|CDD|379414	pfam14011, ESX-1_EspG, EspG family. This family of proteins contains the the EspG1, EspG2 and EspG3 proteins from M. tuberculosis. These proteins are involved in the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis which is important for virulence and intercellular spread. Proteins in this family are typically between 254 and 295 amino acids in length.	1.29098e-54
NC_018078.1|WP_003401488.1|352800_354342_+|type-VII-secretion-system-ESX-3-target-PPE4	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	1.09345e-59
NC_018078.1|WP_009938204.1|332646_333075_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350245	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC25, VapC29, VapC33, VapC37, and VapC39 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	3.90741e-60
NC_018078.1|WP_003401514.1|354713_355004_+|WXG100-family-type-VII-secretion-target	gnl|CDD|227179	COG4842, COG4842, Uncharacterized protein conserved in bacteria [Function unknown].	2.85211e-21
NC_018078.1|WP_003401404.1|331686_332607_+|DUF2236-domain-containing-protein	gnl|CDD|226188	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown].	2.89836e-118
NC_018078.1|WP_003899886.1|330871_331597_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.66172e-07
NC_018078.1|WP_010950374.1|342229_343840_+|PPE-family-protein	gnl|CDD|227938	COG5651, COG5651, PPE-repeat proteins [Cell motility and secretion].	1.45056e-73
NC_018078.1|WP_003401472.1|346887_348504_+|type-VII-secretion-system-ESX-3-subunit-EccB3	gnl|CDD|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	0
NC_018078.1|WP_003401448.1|343863_344772_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	1.10201e-94
NC_018078.1|WP_003401397.1|329643_330264_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.87158e-12

Protein sequences

>NC_018078.1|WP_031655831.1|336437_339176_-|PE-family-protein
MSFVIAAPEVIAAAATDLASLGSSISAANAAAAANTTALMAAGADEVSTAIAALFGAHGQAYQALSAQAQAFHAQFVQALTSGGGAYAAAEAAAVSPLLDPINEFFLANTGRPLIGNGANGAPGTGANGGDGGWLIGNGGAGGSGAAGVNGGAGGNGGAGGLIGNGGAGGAGGVASSGIGGSGGAGGNAMLFGAGGAGGAGGGVVALTGGAGGAGGAGGNAGLLFGAAGVGGAGGFTNGSALGGAGGAGGAGGLFATGGVGGSGGAGSSGGAGGAGGAGGLFGAGGTGGHGGFADSSFGGVGGAGGAGGLFGAGGEGGSGGHSLVAGGDGGAGGNAGMLALGAAGGAGGIGGDGGTLTAGGIGGAGGAGGNAGLLFGSGGSGGAGGFGFADGGQGGPGGNAGTVFGSGGAGGNGGVGQGFAGGIGGAGGTPGLIGNGGNGGNGGASAVTGGNGGIGGTGVLIGNGGNGGSGGIGAGKAGVGGVSGLLLGLDGFNAPASTSPLHTLQQNVLNVVNEPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGSGATGTNGGDGGDGGAGGIFFGTGGTGGAGGVGTTGTGGDGGAGGAAFLMGSGGNGGSGGAGLTAGGDGGDGGNAGSFFGAAGTGGAGASTKAGGTGGTGGNGGLFANGGAGGSGGLGGDAGTGGAGGNGGLFGAGGTGGAGGSLGPGAGGAGGNGGLFGAGGTGGAGGSLGPGAGGAGGNGGLFGAGGTGGSGGAGGNAGLFSLGASGGAGGSGGSSLTDGGGIGGVGGAGGLLFGYGGAGGAGGYSNIGAGGAGGAGGNAGMLSGSGGSGGTGGASGAAKGGVGGNGGTAGVFGNGGDGGAGGFGAGTGGNGGVGGNAVLIGNGGNGGNGGKAGGTPGAGGTSGLLIGENGLNGLP
>NC_018078.1|WP_014830004.1|333375_336174_-|PE-family-protein
MSFVIAAPEVIAAAATDLASLESSIAAANAAAAANTTALLAAGADEVSTAVAALFGAHGQAYQALSAQAQAFHAQFTQALTSGGGAYAAAEAAAVSPLLDPINEFFLANTGRPLIGNGTNGAPGTGADGAPGGWLIGNGGAGGSGAANNAVGGTGGTGGAGGASGLLGSGGAGGAGGVATNTGGIGGAGGTGGNAVLFGAGGASTNTTGGAGGAGGDGGNAGLLFGAAGVGGAGGFALATTASGGAGGAGGAGGMFTDGGVGGVGGKGGFGGAGGAGGNGGLFGAGGTGGAGGTIGAGVAGMGGAGGAGGAGGLFGAGGTGGSGGGGATTGGDGGAGGNAGTLSLGAAGGAGGAGGEGLASAGGDGGAGGDGGNAGMFFGSGGAGGAGGFGRTTGGIGGTGGNAGLLNGSGGAGGAGGAAITGPGGTGGAGGIPGLIGNGGNGGDGGASVTGTGGNGGAGGNGVQIGNGGNGGSGGTGAAAGKAGLGGLGGQLIGLDGSNAPVSTSVHTLQQAALNVVNEPFQTLTGRPLIGNGANGTPGTGAAGGAGGWLFGNGGNGGHGATNTAATATGGAGGAGGILFGTGGNGGTGGIATGAGGIGGAGGAGGVSLLIGSGGTGGNGGNSIGVAGIGGAGGRGGDAGLLFGAAGTGGHGAAGGVPAGVGGAGGNGGLFANGGAGGAGGFNAAGGNGGNGGLFGTGGTGGAGTNFGAGGNGGNGGLFGAGGTGGAAGSGGSGITTGGGGHGGNAGLLSLGASGGAGGSGGASSLAGGAGGNGALLFGFGGAGGAGGHGGAALTSIQQGGAGGAGGNGGLLFGSAGAGGAGGSGANALGAGTGGTGGDGGHAGVFGNGGDGGCRRVWRRYRRQRWCRRQRRADRQRRQRRQRRQSRGHARCRRHRRAAARRERTQRLAIAGRPATTRGVEGISCSPQMMP
>NC_018078.1|WP_011961607.1|333098_333281_-|hypothetical-protein
MGAVIEDALRRELAAARTGGARPTVPVFDAGTGPRPGIDLTSNTVLSEVLDEGLELNSRK
>NC_018078.1|WP_009938204.1|332646_333075_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MFLIDVNVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLTTNRRIFEIPSPRADAFAFVEAVTAQPHHLPTSPGPRHLVLLRKLCDEADASGDLIPDAVLGAIAVEHHCAVVSLDRDFARFASVRHIRPPI
>NC_018078.1|WP_003401404.1|331686_332607_+|DUF2236-domain-containing-protein
MAISLVAHQPIPHVERPMADPPRLQLARRRRSAAGPGGNEDSLMGVALLAGPANVIMELAMPGVGYGVLESRVESGRLDRHPIKRARTTFTYVAVAVAGSDDQKAAFRRAVNKVHAQVYSTPESPVSYHAFDPELQLWVAACLYKGGVDVYRTFVGEMDDEEADHHYRAGMAMGTTLQVPPQMWPPDRAAFDRYWRQSLDRVHIDDVVRDYLYPIVALRIRGIALPGPLRRLSEGIALLITTGFLPQRFRDEMRLPWDATKQRRFDALMAVLRTVNRLMPRFVREFPFNLMLWDLDRRMRRGRPLV
>NC_018078.1|WP_003899886.1|330871_331597_-|TetR/AcrR-family-transcriptional-regulator
MTRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSGQHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
>NC_018078.1|WP_003401399.1|330360_330942_+|VOC-family-protein
MIKPHNTNTEFELGGINHVALVCSDMARTVDFYSNILGMPLIKALDLPGGQGQHFFFDAGNGDCVAFFWFADAPDRVPGLSSPVAIPGIGDITSAVSTMNHLAFHVPAERFDAYRQRLKDKGVRVGPVLNHDDSETQVSAVVHPGVYVRSFYFQDPDGITLEFACWTKEFTTSDAQAVPKTAADRRPPVAADR
>NC_018078.1|WP_003401397.1|329643_330264_-|TetR/AcrR-family-transcriptional-regulator
MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLSDRERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFITETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRRGQPDDQACIQTLANIYYRAIYSKEDSSN
>NC_018078.1|WP_003401394.1|328513_329647_-|hypothetical-protein
MTGRAATPGVIREFVGLPSRTAGRAAAGGHPCQGLYHHSVGRKPKVALIAAHYQIDFSEHYLAEYMAIRGIGFLGWNTRFRGFESSFLLDHALVDIGVGVRWLREVQGVETVVLLGNSGGGSLMAAYQSQAVDPNVTPLDGMRPAAGVTELPAADAYVAAAAHPGRPDVLTAWMDAAVIDENDPVATDPELDLFDERNGPPYSPEFISRYRSAQVKRNHTITDWAESELKRVRAAGFSDRPFSVMRTWADPRMVDPSIEPTKRRPNQCYAGTPVKANRSAHGIAAACTLRGWLGMWSLRVAQTRAAPHLARITCPALVLNAEADTGIFPSDAQQIYDGLASSDKTQVSIDTDHYFTTPGARSEQADTIAKWIAKRWR
>NC_018078.1|WP_009938203.1|326204_328400_-|acyl-CoA-dehydrogenase
MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVENPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFGYGAVPGPFVPSAIASALIAAHDPQAKVLAELATGAAIAAYALDSGLTATRHGDVLVIRGEVRAVPAAAQASVLVLPVAIESRDEWVVLRNDQLEIEAVKSLDPLRPIAHIRANAVDVSDDALLSNLTMTTAHALMSTLLSAEAVGVARWATDTASAYAKIREQFGRPIGQFQAIKHKCAEMIADTERATAAVWDAARALDDAGESSSDVEFAAAVAATLAPATAQRCTQDCIQVHGGIGFTWEHDTNVYYRRALMLAACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKAMPREPRTVAIAEGGWVLPYLPKPWGRAASPVEQIIIAQEFTAGRVKRPQIAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSDLASLATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFLLDMKSEGVQVKPLRELTGKEFFNTVYLDDVFVPDELVLGEVNRGWEVSRNTLTAERVSIGGSDSTFLPTLGEFVDFVRDYRFEGQFDQVARHRAGQLIAEGHATKLLNLRSTLLTLAGGDPMAPAAISKLLSMRTGQGYAEFAVSSFGTDAVIGDTERLPGKWGEYLLASRATTIYGGTSEVQLNIIAERLLGLPRDP
>NC_018078.1|WP_010950374.1|342229_343840_+|PPE-family-protein
MTLWMASPPEVHSALLSSGPGPGSVLSAAGVWSSLSAEYAAVADELIGLLGAVQTGAWQGPSAAAYVAAHAPYLAWLMRASETSAEAAARHETVAAAYTTAVAAMPTLVELAANHTLHGVLVATNFFGINTIPIALNEADYARMWTQAASTMATYQAVAEAAVASAPQTTPAPPILAAEAADDDHDHDHDHGGEPTPLDYLVAEILRIISGGRLIWDPAEGTMNGIPFEDYTDAAQPIWWVVRAIEFSKDFETFVQELFVNPVEAFQFYFELLLFDYPTHIVQIVEALSQSPQLLAVALGSVISNLGAVTGFAGLSGLAGMQPAAIPALAPVAAAPPTLPAVAMAPTMAAPGAAVASAAAPASAPAASTVASATPAPPPAPGAAGFGYPYAIAPPGIGFGSGMSASASAQRKAPQPDSAAAAAAAAAVRDQARARRRRRVTRRGYGDEFMDMNIDVDPDWGPPPGEDPVTSTVASDRGAGHLGFAGTARREAVADAAGMTTLAGDDFGDGPTTPMVPGSWDPDRDAPGSAEPGDRG
>NC_018078.1|WP_003401448.1|343863_344772_+|class-I-SAM-dependent-methyltransferase
MRTEGDSWDITTSVGSTALFVATARALEAQKSDPLVVDPYAEAFCRAVGGSWADVLDGKLPDHKLKSTDFGEHFVNFQGARTKYFDEYFRRAAAAGARQVVILAAGLDSRAYRLPWPDGTTVFELDRPQVLDFKREVLASHGAQPRALRREIAVDLRDDWPQALRDSGFDAAAPSAWIAEGLLIYLPATAQERLFTGIDALAGRRSHVAVEDGAPMGPDEYAAKVEEERAAIAEGAEEHPFFQLVYNERCAPAAEWFGERGWTAVATLLNDYLEAVGRPVPGPESEAGPMFARNTLVSAARV
>NC_018078.1|WP_003898392.1|344995_346891_+|type-VII-secretion-system-ESX-3-AAA-family-ATPase-EccA3
MAGVGEGDSGGVERDDIGMVAASPVASRVNGKVDADVVGRFATCCRALGIAVYQRKRPPDLAAARSGFAALTRVAHDQCDAWTGLAAAGDQSIGVLEAASRTATTAGVLQRQVELADNALGFLYDTGLYLRFRATGPDDFHLAYAAALASTGGPEEFAKANHVVSGITERRAGWRAARWLAVVINYRAERWSDVVKLLTPMVNDPDLDEAFSHAAKITLGTALARLGMFAPALSYLEEPDGPVAVAAVDGALAKALVLRAHVDEESASEVLQDLYAAHPENEQVEQALSDTSFGIVTTTAGRIEARTDPWDPATEPGAEDFVDPAAHERKAALLHEAELQLAEFIGLDEVKRQVSRLKSSVAMELVRKQRGLTVAQRTHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIREVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDKFLDTNEGLRSRFTRNIDFPSYTSHELVEIAHKMAEQRDSVFEQSALHDLEALFAKLAAESTPDTNGISRRSLDIAGNGRFVRNIVERSEEEREFRLDHSEHAGSGEFSDEELMTITADDVGRSVEPLLRGLGLSVRA
>NC_018078.1|WP_003401472.1|346887_348504_+|type-VII-secretion-system-ESX-3-subunit-EccB3
MTNQQHDHDFDHDRRSFASRTPVNNNPDKVVYRRGFVTRHQVTGWRFVMRRIAAGIALHDTRMLVDPLRTQSRAVLMGVLIVITGLIGSFVFSLIRPNGQAGSNAVLADRSTAALYVRVGEQLHPVLNLTSARLIVGRPVSPTTVKSTELDQFPRGNLIGIPGAPERMVQNTSTDANWTVCDGLNAPSRGGADGVGVTVIAGPLEDTGARAAALGPGQAVLVDSGAGTWLLWDGKRSPIDLADHAVTSGLGLGADVPAPRIIASGLFNAIPEAPPLTAPIIPDAGNPASFGVPAPIGAVVSSYALKDSGKTISDTVQYYAVLPDGLQQISPVLAAILRNNNSYGLQQPPRLGADEVAKLPVSRVLDTRRYPSEPVSLVDVTRDPVTCAYWSKPVGAATSSLTLLAGSALPVPDAVHTVELVGAGNGGVATRVALAAGTGYFTQTVGGGPDAPGAGSLFWVSDTGVRYGIDNEPQGVAGGGKAVEALGLNPPPVPIPWSVLSLFVPGPTLSRADALLAHDTLVPDSRPARPVSAEGGYR
>NC_018078.1|WP_003401478.1|348500_352493_+|type-VII-secretion-system-ESX-3-FtsK/SpoIIIE-family-ATPase-EccC3
MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGILIVGMIVALVATGMRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDAERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERDPHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRSIGDVPTGIDLTKVSRITVLGERAQVRAVLRAWIAQAVTWHDPTVLGVALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGPVLADRPAFTGQPTDALRHLLIVVDDPDYDLGASPLAVGRAGVTVVHCSASAPHREQYSDPEKPILRVAHGAIERWQTGGWQPYIDAADQFSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVPALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNMAEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIAAGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILFASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHKGVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAVEPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETIPLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGGPKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVASALEPERIRRTFGELEQLLLSRQQREVFRDRGANGSTPDDGFGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITTPSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVGALRRPADAVPHDQPGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAPHAVGELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTLLRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRWTFAGHTHYLIIDDVDQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPLVDAAAVSGETQQKGSQS
>NC_018078.1|WP_003401485.1|352489_352798_+|type-VII-secretion-system-ESX-3-target-PE5
MTLRVVPEGLAAASAAVEALTARLAAAHASAAPVITAVVPPAADPVSLQTAAGFSAQGVEHAVVTAEGVEELGRAGVGVGESGASYLAGDAAAAATYGVVGG
>NC_018078.1|WP_003401488.1|352800_354342_+|type-VII-secretion-system-ESX-3-target-PPE4
MAAPIWMASPPEVHSALLSNGPGPGSLVAAATAWSQLSAEYASTAAELSGLLGAVPGWAWQGPSAEWYVAAHLPYVAWLTQASADAAGAAAQHEAAAAAYTTALAAMPTLAELAANHVIHTVLVATNFFGINTIPITLNEADYVRMWLQAAAVMGLYQAASGAALASAPRTVPAPTVMNPGGGAASTVGAVNPWQWLLALLQQLWNAYTGFYGWMLQLIWQFLQDPIGNSIKIIIAFLTNPIQALITYGPLLFALGYQIFFNLVGWPTWGMILSSPFLLPAGLGLGLAAIAFLPIVLAPAVIPPASTPLAAAAVAAGSVWPAVSMAVTGAGTAGAATPAAGAAPSAGAAPAPAAPATASFAYAVGGSGDWGPSLGPTVGGRGGIKAPAATVPAAAAAAATRGQSRARRRRRSELRDYGDEFLDMDSDSGFGPSTGDHGAQASERGAGTLGFAGTATKERRVRAVGLTALAGDEFGNGPRMPMVPGTWEQGSNEPEAPDGSGRGGGDGLPHDSK
>NC_018078.1|WP_003401503.1|354390_354684_+|type-VII-secretion-system-protein-EsxG
MSLLDAHIPQLVASQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQGESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAAGTYVAADAAAASTYTGF
>NC_018078.1|WP_003401514.1|354713_355004_+|WXG100-family-type-VII-secretion-target
MSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG
>NC_018078.1|WP_003401521.1|355014_355902_+|type-VII-secretion-system-ESX-3-associated-protein-EspG3
MDATPNAVELTVDNAWFIAETIGAGTFPWVLAITMPYSDAAQRGAFVDRQRDELTRMGLLSPQGVINPAVADWIKVVCFPDRWLDLRYVGPASADGACELLRGIVALRTGTGKTSNKTGNGVVALRNAQLVTFTAMDIDDPRALVPILGVGLAHRPPARFDEFSLPTRVGARADERLRSGVPLGEVVDYLGIPASARPVVESVFSGPRSYVEIVAGCNRDGRHTTTEVGLSIVDTSAGRVLVSPSRAFDGEWVSTFSPGTPFAIAVAIQTLTACLPDGQWFPGQRVSRDFSTQSS

Crispr_ID: NC_018078_3

• CRISPR_ID: NC_018078_3
• CRISPR_location: 369320-370018
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 10 spacers

Consensus repeat of NC_018078_3

Consensus_repeat	Method
TTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTG	CRISPRCasFinder

spacers of NC_018078_3

>3.1|369353|27|NC_018078|CRISPRCasFinder
AACGCACCGGTGTCCACATCGCCCGTG
>3.2|369413|27|NC_018078|CRISPRCasFinder
AGGTAGCCCGTGTTGCCACTGCCCGGG
>3.3|369473|42|NC_018078|CRISPRCasFinder
AAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTG
>3.4|369548|27|NC_018078|CRISPRCasFinder
AAGCCGCCCGAGTTCGCGAGACCGAAG
>3.5|369608|42|NC_018078|CRISPRCasFinder
CCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAG
>3.6|369683|33|NC_018078|CRISPRCasFinder
AGGCTGCCGATCCCGATCTGGCCGTTGCCGGTG
>3.7|369749|27|NC_018078|CRISPRCasFinder
GCGAAGCCGATGTTGTAGCTGCCGGTG
>3.8|369809|57|NC_018078|CRISPRCasFinder
GCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGA
>3.9|369899|27|NC_018078|CRISPRCasFinder
GCCAAGCCGATATCGAAGATCCCGGTG
>3.10|369959|27|NC_018078|CRISPRCasFinder
ACCCCGCCGAAGTTGAGGTCGCCGAGG

CRISPR arrays and Neighbor proteins around NC_018078_3

CRISPR arrays

The CRISPR arrays of NC_018078_3

>merge|NC_018078|3|369320-370018|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATGAACGCACCGGTGTCCACATCGCCCGTGTTCGCCACGCCCGTGTTGTAGTCACCGGTGTTGAGGTAGCCCGTGTTGCCACTGCCCGGGTTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTGAAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTGTTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTGAAGCCGCCCGAGTTCGCGAGACCGAAGTTGCCGGTGCCGGTGTTAAAGATGCCGACGTTGCCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAGTTGAACAGCCCGATGTTGTTGCTGCCCGAGTTGAGGCTGCCGATCCCGATCTGGCCGTTGCCGGTGAGCCCGACGCCGATGTTGTTGTTACCGGTATTCGCGAAGCCGATGTTGTAGCTGCCGGTGTTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTCGCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGATTTGCCAACCCGATGTTGTAGCTGCCCAGGTTCGCCAAGCCGATATCGAAGATCCCGGTGTTGGCGATGCCGATGTTGTTACCGCCGATGTTGACCCCGCCGAAGTTGAGGTCGCCGAGGTTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

>NC_018078|3|1|369320-370018|CRISPRCasFinder
ACCAAGAAGCCGTTGCTGTAGCTGCCGGTAATG	AACGCACCGGTGTCCACATCGCCCGTG
TTCGCCACGCCCGTGTTGTAGTCACCGGTGTTG	AGGTAGCCCGTGTTGCCACTGCCCGGG
TTGAAGCCGCCGGTGTTGAAGCTGCCCGGGTTG	AAGCTGCCGGTGTTGAGGTCCCCGGGGTTGAACACGCCCGTG
TTGGTGCTGCCCGCGTTGCCGATGCCGGTGTTG	AAGCCGCCCGAGTTCGCGAGACCGAAG
TTGCCGGTGCCGGTGTTAAAGATGCCGACGTTG	CCGGTGCCCGAGTTGAAGAACCCGATGTTTCCGCTGCCGGAG
TTGAACAGCCCGATGTTGTTGCTGCCCGAGTTG	AGGCTGCCGATCCCGATCTGGCCGTTGCCGGTG
AGCCCGACGCCGATGTTGTTGTTACCGGTATTC	GCGAAGCCGATGTTGTAGCTGCCGGTG
TTGGCAAAGCCCAGGTTGTCGCTGCCGAAGTTC	GCGAAGCCGATGTTGTAGCTGCCGGCGTTGCCAAAGCCCAGGTTGTCGTCGCCCAGA
TTTGCCAACCCGATGTTGTAGCTGCCCAGGTTC	GCCAAGCCGATATCGAAGATCCCGGTG
TTGGCGATGCCGATGTTGTTACCGCCGATGTTG	ACCCCGCCGAAGTTGAGGTCGCCGAGG
TTGCCGATGCCCAGGTTGGAGTCGCCGGTATTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003401540.1|361810_362614_-|hypothetical-protein	unknown	unknown	gnl|CDD|226848
NC_018078.1|WP_003401555.1|366108_366336_+|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl|CDD|279710
NC_018078.1|WP_003401584.1|378799_379471_+|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl|CDD|162875
NC_018078.1|WP_003401613.1|385375_385762_+|hypothetical-protein	unknown	unknown	gnl|CDD|223403
NC_018078.1|WP_003401571.1|367461_368094_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_018078.1|WP_014297570.1|364199_365966_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003401538.1|361036_361822_+|trans-aconitate-2-methyltransferase	unknown	unknown	gnl|CDD|184509
NC_018078.1|WP_003898398.1|382057_383287_+|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003401560.1|366332_366635_+|toxin-antitoxin-system-toxin	unknown	unknown	unknown
NC_018078.1|WP_003401566.1|366900_367326_+|PIN-domain-nuclease	unknown	unknown	gnl|CDD|350322
NC_018078.1|WP_003401597.1|380816_381473_+|L,D-transpeptidase	unknown	unknown	gnl|CDD|226309
NC_018078.1|WP_003401594.1|379998_380715_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239486
NC_018078.1|WP_003401601.1|381542_382034_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|379275
NC_018078.1|WP_003401563.1|366682_366904_+|type-II-toxin-antitoxin-system-antitoxin-VapB2	unknown	unknown	gnl|CDD|222832
NC_018078.1|WP_003401589.1|379458_379941_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003401621.1|386487_387372_+|family-16-glycosylhydrolase	unknown	unknown	gnl|CDD|225182
NC_018078.1|WP_003401619.1|385764_386427_-|DUF3060-domain-containing-protein	unknown	unknown	gnl|CDD|371435
NC_018078.1|WP_003900117.1|368090_368999_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187670
NC_018078.1|WP_003900119.1|383441_385304_+|Hsp70-family-protein	unknown	unknown	gnl|CDD|223520
NC_018078.1|WP_003401544.1|362623_364021_-|sulfatase	unknown	unknown	gnl|CDD|293751

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003401555.1|366108_366336_+|ribbon-helix-helix-protein,-CopG-family	gnl|CDD|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000113886
NC_018078.1|WP_003401584.1|378799_379471_+|5,6-dimethylbenzimidazole-synthase	gnl|CDD|162875	TIGR02476, BluB, 5,6-dimethylbenzimidazole synthase. A previously published hypothesis that BluB, involved in cobalamin biosynthesis, is EC 1.16.8.1 (cob(II)yrinic acid a,c-diamide reductase) is now contradicted by newer work ascribing a role in 5,6-dimethylbenzimidazole (DMB) biosynthesis. The BluB protein is related to the nitroreductase family (pfam0881). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	6.73571e-73
NC_018078.1|WP_003401613.1|385375_385762_+|hypothetical-protein	gnl|CDD|223403	COG0326, HtpG, Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones].	0.00700797
NC_018078.1|WP_003401571.1|367461_368094_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.46938e-15
NC_018078.1|WP_014297570.1|364199_365966_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	3.68153e-29
NC_018078.1|WP_003401538.1|361036_361822_+|trans-aconitate-2-methyltransferase	gnl|CDD|184509	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional.	8.03642e-167
NC_018078.1|WP_003401540.1|361810_362614_-|hypothetical-protein	gnl|CDD|226848	COG4424, COG4424, Uncharacterized protein conserved in bacteria [Function unknown].	2.12891e-123
NC_018078.1|WP_003401566.1|366900_367326_+|PIN-domain-nuclease	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.62509e-57
NC_018078.1|WP_003401563.1|366682_366904_+|type-II-toxin-antitoxin-system-antitoxin-VapB2	gnl|CDD|222832	PHA01748, PHA01748, hypothetical protein.	0.00852727
NC_018078.1|WP_003401601.1|381542_382034_-|nuclear-transport-factor-2-family-protein	gnl|CDD|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.69655e-31
NC_018078.1|WP_003401594.1|379998_380715_+|phosphatase-PAP2-family-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	2.34145e-31
NC_018078.1|WP_003401597.1|380816_381473_+|L,D-transpeptidase	gnl|CDD|226309	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown].	4.28441e-100
NC_018078.1|WP_003401621.1|386487_387372_+|family-16-glycosylhydrolase	gnl|CDD|225182	COG2273, SKN1, Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism].	9.91964e-52
NC_018078.1|WP_003401619.1|385764_386427_-|DUF3060-domain-containing-protein	gnl|CDD|371435	pfam11259, DUF3060, Protein of unknown function (DUF3060). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed.	1.8339e-21
NC_018078.1|WP_003900117.1|368090_368999_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187670	cd09810, LPOR_like_SDR_c_like, light-dependent protochlorophyllide reductase (LPOR)-like, classical (c)-like SDRs. Classical SDR-like subgroup containing LPOR and related proteins. Protochlorophyllide (Pchlide) reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.69352e-146
NC_018078.1|WP_003900119.1|383441_385304_+|Hsp70-family-protein	gnl|CDD|223520	COG0443, DnaK, Molecular chaperone [Posttranslational modification, protein turnover, chaperones].	3.71262e-67
NC_018078.1|WP_003401544.1|362623_364021_-|sulfatase	gnl|CDD|293751	cd16027, SGSH, N-sulfoglucosamine sulfohydrolase (SGSH; sulfamidase). N-sulfoglucosamine sulfohydrolase (SGSH) belongs to the sulfatase family and catalyses the cleavage of N-linked sulfate groups from the GAGs heparin sulfate and heparin. The active site is characterized by the amino-acid sequence motif C(X)PSR that is highly conserved among most sulfatases. The cysteine residue is post-translationally converted to a formylglycine (FGly) residue, which is crucial for the catalytic process. Loss of function of SGSH results a disease called mucopolysaccharidosis type IIIA (Sanfilippo A syndrome), a fatal childhood-onset neurodegenerative disease with mild facial, visceral and skeletal abnormalities.	5.75322e-137

Protein sequences

>NC_018078.1|WP_003900117.1|368090_368999_+|SDR-family-NAD(P)-dependent-oxidoreductase
MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQVT
>NC_018078.1|WP_003401571.1|367461_368094_+|TetR/AcrR-family-transcriptional-regulator
MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET
>NC_018078.1|WP_003401566.1|366900_367326_+|PIN-domain-nuclease
MTDQRWLIDKSALVRLTDSPDMEIWSNRIERGLVHITGVTRLEVGFSAECGEIARREFREPPLSAMPVEYLTPRIEDRALEVQTLLADRGHHRGPSIPDLLIAATAELSGLTVLHVDKDFDAIAALTGQKTERLTHRPPSA
>NC_018078.1|WP_003401563.1|366682_366904_+|type-II-toxin-antitoxin-system-antitoxin-VapB2
MSDVLIRDIPDDVLASLDAIAARLGLSRTEYIRRRLAQDAQTARVTVTAADLRRLRGAVAGLGDPELMRQAWR
>NC_018078.1|WP_003401560.1|366332_366635_+|toxin-antitoxin-system-toxin
MIAPGDIAPRRDSEHELYVAVLSNALHRAADTGRVITCPFIPGRVPEDLLAMVVAVEQPNGTLLPELVQWLHVAALGAPLGNAGVAALREAASVVTALLC
>NC_018078.1|WP_003401555.1|366108_366336_+|ribbon-helix-helix-protein,-CopG-family
MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRVALRDYTAKTVPALDIDAYAQRVYQANRAAGS
>NC_018078.1|WP_014297570.1|364199_365966_+|PE-family-protein
MSFVIAQPEMIAAAAGELASIRSAINAANAAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAAAFHAQVVRTLTVDAGAYASAEAANAGPNMLAAVNAPAQALLGRPLIGNGANGAPGTGQAGGDGGLLFGNGGNGGSGAPGQAGGAGGAAGFFGNGGNGGDGGAGANGGAGGTAGWFFGFGGNGGAGGIGVAGINGGLGGAGGDGGNAGFFGNGGNGGMGGAGAAGVNAVNPGLATPVTPAANGGNGLNLVGVPGTAGGGADGANGSAIGQAGGAGGDGGNASTSGGIGIAQTGGAGGAGGAGGDGAPGGNGGNGGSVEHTGATGSSASGGNGATGGNGGVGAPGGAGGNGGHVSGGSVNTAGAGGKGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGGAGVSATDIAGTGGRGGNGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIGGHGGDGGSVNTPIGGSEAGDGGKGGLGGDGGGRGIFGQFGAGGAGGAGGVGGAGGAGGTGGGGGNGGAIFNAGTPGAAGTGGDGGVGGTGAAGGKGGAGGSGGVNGATGADGAKGLDGATGGKGNNGNPG
>NC_018078.1|WP_003401544.1|362623_364021_-|sulfatase
MTSERATGQRENLLIVHWHDLGRYLGVYHHPDVYSPRLDRLAAEGILFTRAHATAPLCTPSRGSLFTGRYPQSNGLVGLAHHGWEYRTGVQTLPQLLSESGWYSALFGMQHETSYPKRLGFDEFDVSNSYCEYVVAKAQDWLHNRVPALDGQRFLLTAGFFETHRPYPHERYRPADSAAVELPDYLPDTPEVRQDVAEFYGSIATADEAVGRLLDTLADTGLDASTWVVFVTDHGPAFPRAKSTLYDAGTGIALIIRPPTRRAMAPRVYDELFSGVDLVPTLLDLLRLEVPADVEGVSHAPALLAPDTENAAVRDHVYTAKTYHDSFDPIRAIRTKEYSYIENYAPRPLLDLPWDIQESPAGMAVAPLVKAPRPQRELYDLRADPTETNNLLAGDDSTQGVAAIAADLAVRLHDWRQRTADVIPSDFAGSRIAERYTETYLRIHRKTPTGRSAIAADRGIDEHCS
>NC_018078.1|WP_003401540.1|361810_362614_-|hypothetical-protein
MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT
>NC_018078.1|WP_003401538.1|361036_361822_+|trans-aconitate-2-methyltransferase
MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLTRYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWVPEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGAVVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQQFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG
>NC_018078.1|WP_003401584.1|378799_379471_+|5,6-dimethylbenzimidazole-synthase
MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPSVGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALGAREEEFLALKVEGILDCAELLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLAARSEGLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWSYPSALATDHHHGE
>NC_018078.1|WP_003401589.1|379458_379941_-|hypothetical-protein
MAVIVRKWFGLGRLPADLRCQVEAEGLIYLAEYVAVTRRFTGVIPGLRASHSIASYVGALAFTEQRVLGTLSMVPKLAGRVVDARWDGPQAGAATAEISPTGLQLDLDVADVDPKFSGQLALHFKATIGEDVLSRLPRRSLAFDVPAEYVNLAVGVTYSP
>NC_018078.1|WP_003401594.1|379998_380715_+|phosphatase-PAP2-family-protein
MTRPQALLAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHDIGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLLLACLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLTVLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYLYFLVCLCVFRPPSIFGAQRASHALSPPVEVSRQPEPEVDTAR
>NC_018078.1|WP_003401597.1|380816_381473_+|L,D-transpeptidase
MSRLLALLCAAVCTGCVAVVLAPVSLAVVNPWFANSVGNATQVVSVVGTGGSTAKMDVYQRTAAGWQPLKTGITTHIGSAGMAPEAKSGYPATPMGVYSLDSAFGTAPNPGGGLPYTQVGPNHWWSGDDNSPTFNSMQVCQKSQCPFSTADSENLQIPQYKHSVVMGVNKAKVPGKGSAFFFHTTDGGPTAGCVAIDDATLVQIIRWLRPGAVIAIAK
>NC_018078.1|WP_003401601.1|381542_382034_-|nuclear-transport-factor-2-family-protein
MCCNGVVTPGDPADIAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSVGTELHFTNRADLVDYLRQALGPGVITEHRVTHPEITVTGDTATGIWYLQDRVIVAEFNFMLIGAAFYHDQYRRTTDGWRISATGYDRTYEATMSLAGLNFNIRPGRALAD
>NC_018078.1|WP_003898398.1|382057_383287_+|hypothetical-protein
MSQSRYAGLSRSELAVLLPELLLIGQLIDRSGMAWCIQAFGRQEMLQIAIEEWAGASPIYTKRMQKALNFEGDDVPTIFKGLQLDIGAPPQFMDFRFTLHDRWHGEFHLDHCGALLDVEPMGDDYVVGMCHTIEDPTFDATAIATNPRAQVRPIHRPPRKPADRHPHCAWTVIIDESYPEAEGIPALDAVRETKAATWELDNVDASDDGLVDYSGPLVSDLDFGAFSHSALVRMADEVCLQMHLLNLSFAIAVRKRAKADAQLAISVNTRQLIGVAGLGAERIHRAMALPGGIEGALGVLELHPLLNPAGYVLAETSPDRLVVHNSPAHADGAWISLCTPASVQPLQAIATAVDPHLKVRISGTDTDWTAELIEADAPASELPEVLVAKVSRGSVFQFEPRRSLPLTVK
>NC_018078.1|WP_003900119.1|383441_385304_+|Hsp70-family-protein
MYDPLGLSIGTTNLVAAGNGGPPVTRRAVLTLYPHCAPKIGVPSQNPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAGADASSSEIAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDAIAALTAVNSELGLPHGSVVGLLDFGGSATYVTLVETKSDSRTSDFQPVSATARYQDFSGSQIDQALLLRVIDQFGYGDDVDPASTAAVGQLGQLREQCRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDLIQDPLTGFIYAFDDMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQPGCAAAMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGDVMVIDHEALTDRELAWSQTDFPSEAPARFEGDSYNEGGPCWSMRLNAVEPPKGPAWRRIRVSQLLIGVSAVVAMTAIGGVALTLTAIERRPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAPLPSAAPAPTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTEPPVTTTSTIPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGAGEPQNPFGSLGSG
>NC_018078.1|WP_003401613.1|385375_385762_+|hypothetical-protein
MGDYGPFGFDPDEFDRVIREGSEGLRDAFERIGRFLSSSGAGTGWSAIFEDLSRRSRPAPETAGEAGDGVWAIYTVDADGGARVEQVYATELDALRANKDNTDPKRKVRFLPYGIAVSVLDDPVDEAQ
>NC_018078.1|WP_003401619.1|385764_386427_-|DUF3060-domain-containing-protein
MIVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSGGYTYPPGPPPPPYSYGGPFGGPSPRSSSGNRAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVPTPTAQPATTLPPAGASLSVSGVNVNRTIACNDSIVSVSGMSNTVVITGHCTSLTVSGMRNSVTVDSVDTIEAAGFNNEVTYHSGSPKISNAGGSNSVQQG
>NC_018078.1|WP_003401621.1|386487_387372_+|family-16-glycosylhydrolase
MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPAAATGGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIEDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF

Crispr_ID: NC_018078_4

• CRISPR_ID: NC_018078_4
• CRISPR_location: 692336-692412
• CRISPR_type: TypeV-U4
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018078_4

Consensus_repeat	Method
TGAGGTGCGGCGTGAGCGCGGGT	CRISPRCasFinder

spacers of NC_018078_4

>4.1|692359|31|NC_018078|CRISPRCasFinder
AGCGCGAACGGCAAGCCGAACCGTTGGACCC

CRISPR arrays and Neighbor proteins around NC_018078_4

CRISPR arrays

The CRISPR arrays of NC_018078_4

>merge|NC_018078|4|692336-692412|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGTAGCGCGAACGGCAAGCCGAACCGTTGGACCCTGAGGTGCGGCGTGAGCGCGGGT

>NC_018078|4|2|692336-692412|CRISPRCasFinder
TGAGGTGCGGCGTGAGCGCGGGT	AGCGCGAACGGCAAGCCGAACCGTTGGACCC
TGAGGTGCGGCGTGAGCGCGGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003403119.1|693547_695098_+|MCE-family-protein	unknown	unknown	gnl|CDD|224380
NC_018078.1|WP_003403128.1|695978_697214_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224292
NC_018078.1|WP_003403125.1|695538_695796_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|226603
NC_018078.1|WP_003403039.1|678020_678236_+|CopG-family-transcriptional-regulator	unknown	unknown	gnl|CDD|279710
NC_018078.1|WP_003403137.1|697464_697878_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350248
NC_018078.1|WP_003900973.1|698214_698721_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_018078.1|WP_003403122.1|695149_695542_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350335
NC_018078.1|WP_003900178.1|682195_684583_-|flippase-like-domain-containing-protein	unknown	unknown	gnl|CDD|377103
NC_018078.1|WP_003403095.1|685439_686237_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838
NC_018078.1|WP_003403052.1|678699_679386_-|hypothetical-protein	unknown	unknown	gnl|CDD|378485
NC_018078.1|WP_003403139.1|697874_698111_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224913
NC_018078.1|WP_003403164.1|700166_700478_+|hypothetical-protein	unknown	unknown	gnl|CDD|377032
NC_018078.1|WP_003403101.1|686238_687126_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223838
NC_018078.1|WP_003403144.1|698834_699305_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|236751
NC_018078.1|WP_003403047.1|678232_678640_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|350263
NC_018078.1|WP_003403104.1|687131_688346_+|MCE-family-protein	unknown	unknown	gnl|CDD|378749
NC_018078.1|WP_003403148.1|699348_700110_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_018078.1|WP_003900181.1|689369_690815_+|virulence-factor-Mce-family-protein	unknown	unknown	gnl|CDD|273384
NC_018078.1|WP_003403065.1|684720_685443_+|FadR-family-transcriptional-regulator-Mce2R	unknown	unknown	gnl|CDD|225097
NC_018078.1|WP_003403055.1|679539_682173_+|glycosidase	unknown	unknown	gnl|CDD|226067

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003403119.1|693547_695098_+|MCE-family-protein	gnl|CDD|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	2.75938e-80
NC_018078.1|WP_003403128.1|695978_697214_-|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.27416e-77
NC_018078.1|WP_003403125.1|695538_695796_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	2.38527e-16
NC_018078.1|WP_003403039.1|678020_678236_+|CopG-family-transcriptional-regulator	gnl|CDD|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.000727733
NC_018078.1|WP_003403137.1|697464_697878_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350248	cd18681, PIN_MtVapC27-VapC40_like, VapC-like PIN domain of Mycobacterium tuberculosis VapC27, and VapC40, and related proteins. This subfamily includes Mycobacterium tuberculosis VapC27 and VapC40. It belongs to the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	9.76945e-42
NC_018078.1|WP_003900973.1|698214_698721_-|sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.10494e-27
NC_018078.1|WP_003403122.1|695149_695542_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350335	cd18768, PIN_MtVapC4-C5-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC4, VapC5, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 toxin of the VapBC toxin/antitoxin (TA) system. This family belongs to the PIN_VapC4-5_FitB-like subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. M. tuberculosis VapC4 interacts with, and cleaves tRNA44Cys-GCA. M. tuberculosis VapC5 has endonucleolytic activity with RNA, this activity is low with dsRNA, and no activity has been demonstrated on dsDNA. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.73431e-57
NC_018078.1|WP_003900178.1|682195_684583_-|flippase-like-domain-containing-protein	gnl|CDD|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	2.17737e-22
NC_018078.1|WP_003403095.1|685439_686237_+|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	9.02403e-82
NC_018078.1|WP_003403052.1|678699_679386_-|hypothetical-protein	gnl|CDD|378485	pfam10738, Lpp-LpqN, Probable lipoprotein LpqN. This family is conserved in Mycobacteriaceae and is likely to be a lipoprotein.	5.50369e-72
NC_018078.1|WP_003403139.1|697874_698111_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|224913	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription].	1.50922e-07
NC_018078.1|WP_003403164.1|700166_700478_+|hypothetical-protein	gnl|CDD|377032	pfam03413, PepSY, Peptidase propeptide and YPEB domain. This region is likely to have an protease inhibitory function (personal obs:C Yeats). This model is likely to miss some members of this family as the separation from signal to noise is not clear. The name is derived from Peptidase & Bacillus subtilis YPEB.	0.00241752
NC_018078.1|WP_003403101.1|686238_687126_+|ABC-transporter-permease	gnl|CDD|223838	COG0767, Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	2.8651e-83
NC_018078.1|WP_003403144.1|698834_699305_-|HAMP-domain-containing-protein	gnl|CDD|236751	PRK10755, PRK10755, two-component system sensor histidine kinase PmrB.	1.39186e-13
NC_018078.1|WP_003403047.1|678232_678640_+|PIN-domain-containing-protein	gnl|CDD|350263	cd18696, PIN_MtVapC26-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC26 and related proteins. Mycobacterium tuberculosis VapC26 cleaves 23S rRNA in the Sarcin-Ricin Loop, it is inhibited by the cognate VapB26 antitoxin. This subfamily belongs to the VapC (virulence-associated protein C)-like nuclease family of the PIN domain-like superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.4948e-60
NC_018078.1|WP_003403104.1|687131_688346_+|MCE-family-protein	gnl|CDD|378749	pfam11887, Mce4_CUP1, Cholesterol uptake porter CUP1 of Mce4, putative. Mce4_CUP1 is a family of putative Mce4 transporters of cholesterol. The domain is found associated with pfam02470. The full TCDB classification for this family in conjunction with PF02470 is TC:3.A.1.27.4.	1.49168e-114
NC_018078.1|WP_003403148.1|699348_700110_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.00442e-84
NC_018078.1|WP_003900181.1|689369_690815_+|virulence-factor-Mce-family-protein	gnl|CDD|273384	TIGR00996, Mtu_fam_mce, virulence factor Mce family protein. Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis].	1.51384e-92
NC_018078.1|WP_003403065.1|684720_685443_+|FadR-family-transcriptional-regulator-Mce2R	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	4.76819e-52
NC_018078.1|WP_003403055.1|679539_682173_+|glycosidase	gnl|CDD|226067	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism].	0

Protein sequences

>NC_018078.1|WP_003900181.1|689369_690815_+|virulence-factor-Mce-family-protein
MRTLTEFNRGRVGMMGAVVTVLVVGVAQSFTSVPMLFATPTYYAQFADTGGINTGDKVEIAGVNVGLVRSLAIRGNRVLIGFSLPGKTIGMQSRAAIRTDTILGRKNLEIEPRGSEPLKPNGFLPLAQTTTPYQIYDAFVDVTKAATGWDIDAVKRSLNVLSETFDQTAPHLSAALEGVKAFSDTVGRRGEQIEQLLANANRIARVLGDRSEQVNGLLVNAKTLLAAFKQRSQALRILLTNVSEASAQVSGLITDNPNLNHVLAQLRTVSEELVKRKNELADVAVLLGRYTAALTEAVGSGPFFKAMVVNLLPYQILQPWVDAAFKKRGIDPENFWRSAGLPEFRWPDPNGTRFPNGAPPAAPPVREGTPKHPGPAVPPGTPCSYTPAAGALPRPDTPLPCAGATVGPFGGPDFPAPLDVQPSPPNPDGPPPTPGILSAGRPGEPAPAVPGIPMPLPPNAPPGARTQPLEPFPDGTGGSNQ
>NC_018078.1|WP_003403104.1|687131_688346_+|MCE-family-protein
MPTLVTRKNRRAWLYVEGVVLLLVGALVLVLVYKQFRGEFTPKTELTMVASRAGLVMEAGSKVTYNGVEIGRVGSISEIERDGRPAAKLVLDVNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIPQQQRISSHDVIDVGSVTTEFNTLFETITSIAEKVDPIELNATLSAVAQALDGLGGKFGESIVNGNQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLTSQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTYSPELFCMIRNFHDAAPKVADAVGGNGYSLAAAGTILGAPNPYVYPDNLPRVNAHGGPGGRPGCWQTITRELWPAPYLVMDTGASLAPYNHVELGQPMFTEYVWGRQYGENTINP
>NC_018078.1|WP_003403101.1|686238_687126_+|ABC-transporter-permease
MVESSTASAAAVLRARYPRTAASLDRYGGGTARRLERTGTFARFTRISVVQIGWALRRYRRETLRLVAEIGMGTGAMAVVGGTVAIIGFVTLSGGSLIAIQGFASLGNIGVEAFTGFFAALANTRVAAPIVSGVALAATVGAGATAQLGAMRISEEIDALEVMGIKSISFLVSTRILGGLVVIMPLYALALDMAFTSGQVVTTVFYGQSNGTYEHYFRTFLRPEDVGWSVVEVVIIAVVVMITHCYYGYTASGGPVGVGQAVGRSMRFSLVSVVVVVLLAELALYGVDPNFNLTV
>NC_018078.1|WP_003403095.1|685439_686237_+|ABC-transporter-permease
MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGLPEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIALFATNVVLTTIGVRFGTGH
>NC_018078.1|WP_003403065.1|684720_685443_+|FadR-family-transcriptional-regulator-Mce2R
MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVTTVRDFRRHAGLDLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDSLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLAALTTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANTSLMAVLVSQASRQ
>NC_018078.1|WP_003900178.1|682195_684583_-|flippase-like-domain-containing-protein
MRVDGRDIGVSGNLLQPLTRRTNDIIRAVLAAIYLVAVITSSLITRPQWVALEKSISEIVGVLSPSQSDLVYLGYGLAILALPFVILIGLIVSRQWKLLGAYAAAGLMAVLPLSISSSRIAAPRWHFDLSDRLATLLAQFLDDPRWIAMLAAVLTVSGPWLPARWRHWWWALLLAFVPIHLVVSAIVPARSLLGLAVGWLVGALVVLVVGTPALEVPLDGAIRALAKRGFAVSGLAVVRPAGPGPLVLSAACEQPNAGACSEALIELYGPHQSGGGALRQLWLKLTLRGTETAPLQASMRRAVEHRALMAIAFGDLGMANTTVIAVSPLDRGWTLYAHRPARGIGISECTKTTPTAHVWEALRTLHDQQISHGDLCSAEITVDNGAVLFGGFGEAEYGATDAQLQSDLAQLLVTTSALYDAEAAVTAAIDTFGKQAILAASRRLTKSAVPKRIRESITDPNAVIASTRAEVMRQTGADQIKAETITRFSRGQLIQLVLIGALVYVAYPFISTVPTFFSQLRTANWWWALLGLAVSALTYVGAAAALWACADGLVGFWKLSIMQVANTFAATTTPAGVGGLALSTRFLQKGGLTAVRATAAVALQQSVQVIVHLVLLILFSALAGTSTDLSHFVPNATVLYLIAGVALGIVGTFLFVPKLRRWLATAVRPKLREVTNDLIALAREPKRLALIVLGCAGTTLGAALALWASIEAFGGGTTFVTVTVVTMVGGTLASAAPTPGGVGAVEAALIGGLAAFGVPAALGVPSVLLYRLLTCWLPVFAGWQVMHWLTRHEMI
>NC_018078.1|WP_003403055.1|679539_682173_+|glycosidase
MRARRLRRALAALLAVAGLFVPFIVGVPTAYDGEPVFVAIPVEHVNTLIGTGTGAAIVGEINNFPGASVPFGMVQYSPDTVDNYAGYDYDNPHSTGFSMTHASVGCPAFGDISMLPTTTPLGSQPWSAWEEIAHDDTEVGVPGYYTVRFPGTGVIAELTATTRTGVGRFRYPRNGWPALFHVRSGASLAGNYAATLQIEDNTTITGSATSGGFCGKKNLYTVYFAMKFSQPFSSYGTWDGYAVYPGSHSMNSSYSGGYVGFPAGSVLEVRTALSYVSVDGARANLDAEGGASFDDIRAATSSEWNAALSRIAVAGRGPGDVDTFYTCLYRSLLHPNTFNDVDGRYIGFDGVIHSVASGHTHYANFSDWDTYRSLAPLQGLLFPQRASDMIQSLVTDAEQSGAYPRWALANSATGMMSGDSVVPLIVNLYAFGARDFDLKSALHYMVNAATQGGVGLDGFLERPGIAAYLRLGYGPQTAEFRANGRIAGASVTLEWSVDDFAISRFADSLGDTATAAVFQNRSQYWQNLFNPTTGYISPRSAAGFFPDGPGFVAYPSGFGQDGYDEGNAEQYLWWVPHNVAGLVTALGGRTAVVKRLDRFTKKLNVGPNEPYLWAGNEPGFGVPWLYNYIGQPWKTQRTVDRVRGLFGPTPGGAPGNDDLGALSSWYVWAALGLYPSTPGTTILTVNTPLFDRAVIALPTGKSIQITAPGASGRNRLKYIDGLTIDRQPSNQTFLPESIVRTGGDLTFSLAGTPNKVWGTAASAAPPSFGAGSSAVTVNIARPIIGIVPGATGTVTVDAQRMIDGVDDYTVTPTSYVVGIAAEPLSGQFDDDGAVSASVAITVARSVPSGYYPIYVTTSAGDSARTLIVLVVVAEAVE
>NC_018078.1|WP_003403052.1|678699_679386_-|hypothetical-protein
MKHFTAAVATVALSLALAGCSFNIKTDSAPTTSPTTTSPTTSTTTTSATTSAQAAGPNYTIADYIRDNHIQETPVHHGDPGSPTIDLPVPDDWRLLPESSRAPYGGIVYTQPADPNDPPTIVAILSKLTGDIDPAKVLQFAPGELKNLPGFQGSGDGSAATLGGFSAWQLGGSYSKNGKLRTVAQKTVVIPSQGAVFVLQLNADALDDETMTLMDAANVIDEQTTITP
>NC_018078.1|WP_003403047.1|678232_678640_+|PIN-domain-containing-protein
MIIDTSALLAYFDAAEPDHAAVSECIDSSADALVVSPYVVAELDYLVATRVGVDAELAVLRELAGGAWELANCGAAEIEQAARIVTKYQDQRIGIADAANVVLADRYRTRTILTLDRRHFSALRPIGGGRFTVIP
>NC_018078.1|WP_003403039.1|678020_678236_+|CopG-family-transcriptional-regulator
MDKTTVYLPDELKAAVKRAARQRGVSEAQVIRESIRAAVGGAKPPPRGGLYAGSEPIARRVDELLAGFGER
>NC_018078.1|WP_003403119.1|693547_695098_+|MCE-family-protein
MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIPSLVGIGRYTLYAELPRSGGLYRTANVTYRGITIGKVTGVEPTERGARATMSIDNGYQIPTDASANVHSVSAVGEQFVDLVSTRTSGPYLRHGQTITTTTVPSQIGPALDAANRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAHDVRGSLEDIDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPAVRSILANAAPTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQALVFLPQSGAIAQSVTTEFPGQAGLGVGGLALNQPPPCLTGFLPASEWRSPADTSTAPLPKGTYCRIPMDASNVVRGARNNPCVDVPGKRAATPRECRSNEAYVPGGTNPWYGDPNQMLSCPAPAARCDQPVKPGQVIPAPSVNNGINPLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPSTFPTTIYDVQSGKVVAPDGVVYSVEASTHAGADGWKVMLAPTG
>NC_018078.1|WP_003403122.1|695149_695542_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MNVRRALADTSVFIGIEATRFDPDRFAGYEWGVSVVTLGELRLGVLQASGPEAAARRLSTYQLAQRFEPLGIDEAVSEAWALLVSKLRAAKLRVPINDSWIAATAVAHGIAILTQDNDYAAMPDVEVITI
>NC_018078.1|WP_003403125.1|695538_695796_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MSATIPARDLRNHTAEVLRRVAAGEEIEVLKDNRPVARIVPLKRRRQWLPAAEVIGELVRLGPDTTNLGEELRETLTQTTDDVRW
>NC_018078.1|WP_003403128.1|695978_697214_-|ATP-binding-protein
MGVVERAIAPSVLAALADTPVVVVNGARQVGKTTLVARLDYPGSSEVVSLDDVANRDAARDDPRAFVSRPVDTLVIDEAQLEPGLFRAIKAEVDRDRRPGRFLLTGSARLLSAPDMADALVGRVEIIELWPFSQGERAGIADGFVDALFTAPRELIHGSDMRRADLVDRIATGGFPDIVARSPSRRRAWFDNYLTTATQSVIREISPIERLAEMPRVLRLCAARTGAELNVSALANDLSIPARTTAGYLALLEAAFLIHRVPAWSTNLSRKVIRRPKLVVSDSGLACHLLGVTGATLDRPGRPLGPLLETFVANEIRKQLTWSTERPSLWHFRDRGGAEVDLVLEHPDGRVCGIEVKATSTPRAEDLRGLRYLAERLDDRFQFGVLLTAAPEATPFGPTLAALPVSTLWAG
>NC_018078.1|WP_003403137.1|697464_697878_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MKPPLAVDTSVAIPLLVRTHTAHAAVVAWWAHREAALCGHALAETYSVLTRLPRDLRLAPMDAARLLTERFAAPLLLSSRTTEHLPRVLAQFEITGGAVYDALVALAAAEHRAELATRDARAKDTYEKIGVHVVVAA
>NC_018078.1|WP_003403139.1|697874_698111_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKAVVDAAGRIVVPKPLREALGLQPGSTVEISRYGAGLHLIPTGRTARLEEENGVLVATGETTIDDEVVFGLIDSGRK
>NC_018078.1|WP_003900973.1|698214_698721_-|sensor-histidine-kinase
MPITPLLHESVARFAATGADITTRAEPDLFVSIDPDHLRRILTAVLDNAITHGDGEIAVTAHARDGAVDIGVRDHGPGFADHFLPVAFDRFTRADTARGGRGSGLGLAIVAALTTTHGGHANATNHPDGGAELRITLPTPRPPFHEELPRITSSDTKDPNREHDTSDQ
>NC_018078.1|WP_003403144.1|698834_699305_-|HAMP-domain-containing-protein
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
>NC_018078.1|WP_003403148.1|699348_700110_-|response-regulator-transcription-factor
MADETTMRAGRGPGRACGRVSGVRILVVEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR
>NC_018078.1|WP_003403164.1|700166_700478_+|hypothetical-protein
MNRIVQFGVSAVAAAAIGIGAGSGIAAAFDGEDEVTGPDADRARAAAVQAVPGGTAGEVETETGEGAAAYGVLVTRPDGTRVEVHLDRDFRVLDTEPADGDGG

Crispr_ID: NC_018078_5

• CRISPR_ID: NC_018078_5
• CRISPR_location: 841689-841811
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_018078_5

Consensus_repeat	Method
GCCGCCGGCCCCGCCGGCCCCGCCGGTGCCG--------GCG	PILER-CR

spacers of NC_018078_5

>5.1|841723|14|NC_018078|PILER-CR
GACGCGGGTTTGCT
>5.2|841771|11|NC_018078|PILER-CR
TCCGCCACCGG

CRISPR arrays and Neighbor proteins around NC_018078_5

CRISPR arrays

The CRISPR arrays of NC_018078_5

>merge|NC_018078|5|841689-841811|PILER-CR
GGCAACGGCGGGGCCGGCGGGGCCGGCGGCGACGCGGGTTTGCTCGTCGGCTCCGGCGGGGCCGGCGGGGCCGGCGCCTCCGCCACCGGCGCCGCCACCGGCGGGGACGGCGGGGCCGGCGGC

>NC_018078|5|3|841689-841811|PILER-CR
GGCAACGGCGGGGCCGGCGGGGCCGGCGGCGACG	CGGGTTTGCTCGTC
GGCTCCGGCGGGGCCGGCGGGGCCGGCGCCTCCG	CCACCGGCGCC
GCCACCGGCGGGGACGGCGGGGCCGGCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003403839.1|842940_843078_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003898568.1|831859_832666_+|DUF4226-domain-containing-protein	unknown	unknown	gnl|CDD|371237
NC_018078.1|WP_003898574.1|849306_851244_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_018078.1|WP_003403847.1|845624_847157_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143404
NC_018078.1|WP_003403844.1|843550_844435_-|3-hydroxyisobutyrate-dehydrogenase	unknown	unknown	gnl|CDD|130753
NC_018078.1|WP_003403850.1|847362_849117_+|PE-domain-containing-protein	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003403834.1|842150_842408_+|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	gnl|CDD|279710
NC_018078.1|WP_003403741.1|831066_831615_+|TIGR03086-family-protein	unknown	unknown	gnl|CDD|274424
NC_018078.1|WP_003403841.1|843236_843482_+|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003901010.1|836158_836686_+|hypothetical-protein	unknown	unknown	gnl|CDD|274800
NC_018078.1|WP_003403820.1|834890_835448_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003901008.1|832780_833308_+|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003906436.1|830705_830918_+|PE-domain-containing-protein	unknown	unknown	unknown
NC_018078.1|WP_003403845.1|844445_845618_-|acyl-CoA-dehydrogenase-FadE9	unknown	unknown	gnl|CDD|173851
NC_018078.1|WP_003403837.1|842431_842860_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350245
NC_018078.1|WP_003403827.1|835444_835951_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NC_018078.1|WP_003403828.1|836063_836210_-|hypothetical-protein	unknown	unknown	gnl|CDD|130753
NC_018078.1|WP_003901009.1|833985_834513_+|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003403862.1|851944_852670_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003403738.1|830211_830709_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003898568.1|831859_832666_+|DUF4226-domain-containing-protein	gnl|CDD|371237	pfam10774, DUF4226, Domain of unknown function (DUF4226). This family of mycobacterial proteins are uncharacterized.	4.68804e-24
NC_018078.1|WP_003898574.1|849306_851244_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.8545e-82
NC_018078.1|WP_003403847.1|845624_847157_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NC_018078.1|WP_003403834.1|842150_842408_+|ribbon-helix-helix-protein,-CopG-family	gnl|CDD|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.00885702
NC_018078.1|WP_003403741.1|831066_831615_+|TIGR03086-family-protein	gnl|CDD|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	3.64194e-51
NC_018078.1|WP_003403844.1|843550_844435_-|3-hydroxyisobutyrate-dehydrogenase	gnl|CDD|130753	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase. 3-hydroxyisobutyrate dehydrogenase is an enzyme that catalyzes the NAD+-dependent oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde of the valine catabolism pathway. In Pseudomonas aeruginosa, 3-hydroxyisobutyrate dehydrogenase (mmsB) is co-induced with methylmalonate-semialdehyde dehydrogenase (mmsA) when grown on medium containing valine as the sole carbon source. The positive transcriptional regulator of this operon (mmsR) is located upstream of these genes and has been identified as a member of the XylS/AraC family of transcriptional regulators. 3-hydroxyisobutyrate dehydrogenase shares high sequence homology to the characterized 3-hydroxyisobutyrate dehydrogenase from rat liver with conservation of proposed NAD+ binding residues at the N-terminus (G-8,10,13,24 and D-31). This enzyme belongs to the 3-hydroxyacid dehydrogenase family, sharing a common evolutionary origin and enzymatic mechanism with 6-phosphogluconate. HIBADH exhibits sequence similarity to the NAD binding domain of 6-phosphogluconate dehydrogenase above trusted (pfam03446). [Energy metabolism, Amino acids and amines].	3.51879e-107
NC_018078.1|WP_003901010.1|836158_836686_+|hypothetical-protein	gnl|CDD|274800	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase. A conserved gene neighborhood widely spread in the Actinobacteria contains this uncharacterized DEAH-box family helicase encoded convergently towards an operon of genes for protein homologous to type II secretion and pilus formation proteins. The context suggests that this helicase may play a role in conjugal transfer of DNA.	1.97932e-11
NC_018078.1|WP_003403850.1|847362_849117_+|PE-domain-containing-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.38913e-31
NC_018078.1|WP_003901009.1|833985_834513_+|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.95525e-20
NC_018078.1|WP_003403845.1|844445_845618_-|acyl-CoA-dehydrogenase-FadE9	gnl|CDD|173851	cd01162, IBD, Isobutyryl-CoA dehydrogenase. Isobutyryl-CoA dehydrogenase (IBD) catalyzes the alpha, beta- dehydrogenation of short branched chain acyl-CoA intermediates in valine catabolism. It is predicted to be a homotetramer.	0
NC_018078.1|WP_003403827.1|835444_835951_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.38196e-09
NC_018078.1|WP_003403828.1|836063_836210_-|hypothetical-protein	gnl|CDD|130753	TIGR01692, 3-hydroxyisobutyrate_dehydrogenase_mitochondrial, 3-hydroxyisobutyrate dehydrogenase. 3-hydroxyisobutyrate dehydrogenase is an enzyme that catalyzes the NAD+-dependent oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde of the valine catabolism pathway. In Pseudomonas aeruginosa, 3-hydroxyisobutyrate dehydrogenase (mmsB) is co-induced with methylmalonate-semialdehyde dehydrogenase (mmsA) when grown on medium containing valine as the sole carbon source. The positive transcriptional regulator of this operon (mmsR) is located upstream of these genes and has been identified as a member of the XylS/AraC family of transcriptional regulators. 3-hydroxyisobutyrate dehydrogenase shares high sequence homology to the characterized 3-hydroxyisobutyrate dehydrogenase from rat liver with conservation of proposed NAD+ binding residues at the N-terminus (G-8,10,13,24 and D-31). This enzyme belongs to the 3-hydroxyacid dehydrogenase family, sharing a common evolutionary origin and enzymatic mechanism with 6-phosphogluconate. HIBADH exhibits sequence similarity to the NAD binding domain of 6-phosphogluconate dehydrogenase above trusted (pfam03446). [Energy metabolism, Amino acids and amines].	6.18581e-07
NC_018078.1|WP_003403837.1|842431_842860_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350245	cd18678, PIN_MtVapC25_VapC33-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC25, VapC33, and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC25, VapC29, VapC33, VapC37, and VapC39 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.48948e-57
NC_018078.1|WP_003403738.1|830211_830709_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.59277e-21

Protein sequences

>NC_018078.1|WP_003901010.1|836158_836686_+|hypothetical-protein
MGPPHRSRPPLPSPGPTCQVLPTTAVIHTVTAEALGRIGIDAPRIPGSLDVAAHAAIGLLPLVAGCDRRHRRPVRGARAGRAAQVSLCMTAIRVEPVSSNAVCTGPAAQVGDQSRSPQRDYAHQALQPDVPRRRARRHRPRRCSAKTGSSSSTMRCTCHQNQCLWSSGVSWALAR
>NC_018078.1|WP_003403828.1|836063_836210_-|hypothetical-protein
MLGLAMEAVASTGAAAPLGSHAAQIYAKFAADHADLDFSAVIETLRGS
>NC_018078.1|WP_003403827.1|835444_835951_-|helix-turn-helix-domain-containing-protein
METLLKTSEAAQILGVSRQHVVNMCDRGEMVCVHVGSHRRVPSSEVERVTSRRLTREEERSLWLHRALLSPLLTEPDTVVSAARENLRRWSGMHRRDGMAGWYFTKWQRVLNDGLDAVMHVLTSPSEDAREMRQNSPFAGILPEATRVAVLRSFKDHWDREHERAMTE
>NC_018078.1|WP_003403820.1|834890_835448_-|hypothetical-protein
MTRQQLAHLLRRACAVVGDVDVLVLGSQSILGSFDENELPPQATASQEADIAFVNDPARDKADHVDVAIGEMSDFHRSNGVYAEGVHIDTAILPNGWRDRLVSWTVESSRPAKPRFLEPHDLAVAKLAAGREKDKAFVAALIRSGLLDVGVIQARVLLLPEETDPRIGQRIAAWLNYYGAGNHSS
>NC_018078.1|WP_003901009.1|833985_834513_+|PE-family-protein
MSFVIAAPEAIAAAATDLASIGSTIGAANAAAAANTTAVLAAGADQVSVAIAAAFGAHGQAYQALSAQAATFHIQFVQALTAGAGSYAAAEAASAASITSPLLDAINAPFLAALGRPLIGNGADGAPGTGAAGGAGGLLFGNGGAGGSGAPGGAGGLLFGNGGAGGPGASGGALG
>NC_018078.1|WP_003901008.1|832780_833308_+|hypothetical-protein
MLPKNTRPTSETAEEFWDNSLWCSWGDRETGYTRTVTVSICQVADGEREAEGVRDMMRLECPAGLDLRTPNPEAYEITGQRPGEFVFVLGYLGHVRAIVGNCYIEIMPMGTRVELSKLADVALDIGRSVGCSAYENDFTLPDIPTQWRNQPLGWYTQGLAPYLPGLSDPKDAAEG
>NC_018078.1|WP_003898568.1|831859_832666_+|DUF4226-domain-containing-protein
MVLTRRAREVALTQHIGVSAETDRAVVPKLRQAYDSLVCGRRRLGAIGAEIENAVAHQRALGLDTPAGARNFSRFLATKAHDITRVLAATAAESQAGAARLRSLASSYQAVGFGPKPQEPPPDPVPFPPYQPKVWAACRARGQDPDKVVRTFHHAPMSARFRSLPAGDSVLYCGNDKYGLLHIQAKHGRQWHDIADARWPSAGNWRYLADYAIGATLAYPERVEYNQDNDTFAVYRRMSLPDGRYVFTTRVIISARDGKIITAFPQTT
>NC_018078.1|WP_003403741.1|831066_831615_+|TIGR03086-family-protein
MDPLMAHQRAQDAFAALLANVRADQLGGPTPCSEWTINDLIEHVVGGNEQVGRWAASPIEPPARPDGLVAAHQAAAAVAHEIFAAPGGMSATFKLPLGEVPGQVFIGLRTTDVLTHAWDLAAATGQSTDLDPELAVERLAAARALVGPQFRGPGKPFADEKPCPRERPPADQLAAFLGRTVR
>NC_018078.1|WP_003906436.1|830705_830918_+|PE-domain-containing-protein
MRAGRRVSAQCRAEMGAYASARARLGAQPATFHDQFVRALTRARARMRPPRPAGLLLGNGGARRYPAAGS
>NC_018078.1|WP_003403738.1|830211_830709_+|MarR-family-transcriptional-regulator
MASDNRDPIAAARANWERSGWGDVSLGMVAVTSVMRAHQILLARVETALRPYDLSFSRFELLRLLAFSRIGALPITKASDRLQVHVTSVTHAIRRLEADGLVRRVPHPTDGRTTLVQITELGRSTVEDATVTLNEQVFANVGMGAEESQALVSAVETLRRNAGDF
>NC_018078.1|WP_003403834.1|842150_842408_+|ribbon-helix-helix-protein,-CopG-family
MRTTVSISDEILAAAKRRARERGQSLGAVIEDALRREFAAAHVGGARPTVPVFDGGTGPRRGIDLTSNRALSEVLDEGLELNSRK
>NC_018078.1|WP_003403837.1|842431_842860_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MFLLDANVLLAAHRGDHPNHRTVRPWFDRLLAADDPFTVPNLVWASFLRLATNRRIFEIPSPRAEAFAFVEAVTAQPHHLPTNPGPRHLMLLRKLCDEADASGDLIPDAVLAAIAVGHHCAVVSLDRDFARFASVRHIRPPL
>NC_018078.1|WP_003403839.1|842940_843078_-|hypothetical-protein
MVRKHAFHWRYDSTEELELLNQLWQLVSLRLNFFTPTKKALGFRP
>NC_018078.1|WP_003403841.1|843236_843482_+|hypothetical-protein
MRAIVGDCVIHIMPMGTGVELSKLADLALDIGRSVGCSAYENDFTLPDIPTQWRNQPLGWYTQGLAPYLPGLSDPKDAAEG
>NC_018078.1|WP_003403844.1|843550_844435_-|3-hydroxyisobutyrate-dehydrogenase
MTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVITMLPTGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALMNKDLGLAMDAVAATGATAPLGSHAADIYAKFAADHADLDFSAVIHTLRARADA
>NC_018078.1|WP_003403845.1|844445_845618_-|acyl-CoA-dehydrogenase-FadE9
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGVRIFEQLAIADPVTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFISGAAASDVYVVMARTGAEGPRGVSAFIVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAMSGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVELCAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRATV
>NC_018078.1|WP_003403847.1|845624_847157_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAAWNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLLKGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDPSVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAATGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLRARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDLTFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHEYGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAAIQFYTKVKTVTSRWPSGIKDGAEFVIPTMS
>NC_018078.1|WP_003403850.1|847362_849117_+|PE-domain-containing-protein
MSFVIVARDALAAAAADLAQIGSAVNAGNLAAANPTTAVAAAAADEVSAALAALFGAHAREYQAAAAQAAAYHEQFVHRLSAAATSYAVTEVTIATSLRGALGSAPASVSDGFQAFVYGPIHATGQQWINSPVGEALAPIVNAPTNVLLGRDLIGNGVTGTAAAPNGGPGGLLFGDGGAGYTGGNGGSAGLIGNGGTGGAGFAGGVGGMGGTGGWLMGNGGMGGAGGVGGNGGAGGQALLFGNGGLGGAGGAGGVDGAIGRGGWFIGTGGMATIGGGGNGQSIVIDFVRHGQTPGNAAMLIDTAVPGPGLTALGQQQAQAIANALAAKGPYAGIFDSQLIRTQQTAAPLANLLGMAPQVLPGLNEIHAGIFEDLPQISPAGLLYLVGPIAWTLGFPIVPMLAPGSTDVNGIVFNRAFTGAVQTIYDASLANPVVAADGNITSVAYSSAFTIGVGTMMNVDNPHPLLLLTHPVPNTGAVVVQGNPEGGWTLVSWDGIPVGPASLPTALFVDVRELITAPQYAAYDIWESLFTGDPAAVINAVRDGADEVGAAVVQFPHAVADDVIDATGHPYLSGLPIGLPSLIP
>NC_018078.1|WP_003898574.1|849306_851244_-|PPE-family-protein
MVGFAWLPPETNSLRMYLGAGSRPLLAAAGAWDGLAEELHAAASSFGSVTSELAGGAWQGPASAAMANAAGPYASWLTAAGAQAELAARQARAAAGAFEEALAGVVHPAVVQANRVRTWLLAVSNVFGQNAPAIAAMESTYEQMWAQDVAVMAGYHAASSAAAAQLASWQPALPNINLGVGNIGNLNVGNGNTGDYNLGNGNLGNANFGGGNGSAFHGQISSFNVGSGNIGNFNLGSGNGNVGIGPSSFNVGSGNIGNANVGGGNSGDNNFGFGNFGNANIGIGNAGPNMSSPAVPTPGNGNVGIGNGGNGNFGGGNTGNANIGLGNVGDGNVGFGNSGSYNFGFGNTGNNNIGIGLTGSNQIGFGGLNSGSGNIGFGNSGTGNIGFFNSGSGNFGVGNSGVTNTGVANSGNINTGFGNSGFINTGFGNALSVNTGFGNSGQANTGIGNAGDFNTGNFNGGIINTGSFNSGAFNSGSFNGGDANSGFLNSGLTNTGFANSGNINTGGFNAGNLNTGFGNTTDGLGENSGFGNAGSGNSGFNNSGRGNSGAQNVGNLQISGFANSGQSVTGYNNSVSVTSGFGNKGTGLFSGFMSGFGNTGFLQSGFGNLEANPDNNSATSGFGNSGKQDSGGFNSIDFVSGFFHR
>NC_018078.1|WP_003403862.1|851944_852670_-|hypothetical-protein
MNLGQTLVGIATWPARAGLAAADTGLNMAGAAVDMAKQALGDAGGASGSTSMANMLGIDDTIARANRLARLLDDDMPLGRAIAPNGPMDRMLRPGGVVDLLTQPGGLLDRLTAEGGAMQRALQPGGLADQLLAEDGLIERVLSEDGLADRLLAEGGLIDKITAKDGPLEQLADVADTLARLTPGMEALEPAIATLQDAVIALTMVVNPLSSIAERIPLPGRRPARRSSSRSVRSQRVVDSE

Crispr_ID: NC_018078_6

• CRISPR_ID: NC_018078_6
• CRISPR_location: 926467-927414
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 19 spacers
• Cas_protein_info: csa3

Consensus repeat of NC_018078_6

Consensus_repeat	Method
CGGGGCCGGCGGNNCCGGCGG	CRT

spacers of NC_018078_6

>6.1|926485|57|NC_018078|CRT
CGGGTCCGGCGTCAGCGGCGGGGCGGGCGGAGATGGCGGGGCCGGCGGGATCTTGTT
>6.2|926560|39|NC_018078|CRT
CGGCGCGGGCGGGGCCGTCACGGGAACCGGCGCCACCGG
>6.3|926617|18|NC_018078|CRT
CGGTGGAGCCTTGCTGTT
>6.4|926653|42|NC_018078|CRT
TGGAGCCGGCGGGTCCAGCGGGATTGGCGGGTTCGCCGCGGG
>6.5|926713|27|NC_018078|CRT
AGGGGCCGGTGGGCTGTTCAACGGCGG
>6.6|926758|36|NC_018078|CRT
CGGGTCCGGCGTCAGCGGCGGGGCTGGCGGGGAGGG
>6.7|926812|18|NC_018078|CRT
TGGCCTGTTCGCCGGTGG
>6.8|926848|21|NC_018078|CRT
CGGATCGGGCAACAACGTCGG
>6.9|926887|18|NC_018078|CRT
TGGGGTCGGTGGGCTGTT
>6.10|926923|27|NC_018078|CRT
CGGATCCGGCGGCGGCGGTAGCGTTGC
>6.11|926968|39|NC_018078|CRT
CGGCAACGCGGGCTTGCTCGCCCCCGGTCTCGCCGGCGG
>6.12|927025|21|NC_018078|CRT
GCAGGGTTTTGACACCGGCGG
>6.13|927064|30|NC_018078|CRT
CGACGCCGGCCTGCTGGTCGGCTCCGGCGG
>6.14|927112|30|NC_018078|CRT
ATTCGGCCTCACTACGGGTGGGCCTGGGGC
>6.15|927160|30|NC_018078|CRT
CCTGCTGTTCGGCTCCGGCGGCGCTGGCGG
>6.16|927208|24|NC_018078|CRT
AACCGACCTCGGCGGCGCTGGCGG
>6.17|927250|36|NC_018078|CRT
GCTGATCGGCAACGGCGGTAACGGCGGGGCCGGCGG
>6.18|927304|39|NC_018078|CRT
CGGGGACGGCGGGCCCGGTGGAGCCGCCTTCGGGCTCGG
>6.19|927361|36|NC_018078|CRT
CAACGGGGGGACCGGCACGTCCGCGGGCAGCCCCGG

CRISPR arrays and Neighbor proteins around NC_018078_6

CRISPR arrays

The CRISPR arrays of NC_018078_6

>merge|NC_018078|6|926467-927414|CRT
CGGCGGCGGAGGGACCGGCGGGTCCGGCGTCAGCGGCGGGGCGGGCGGAGATGGCGGGGCCGGCGGGATCTTGTTCGGCGCCGGCGGGGCCGGCGGCGCGGGCGGGGCCGTCACGGGAACCGGCGCCACCGGCGGGTCCGGTGGGGCCGGCGGTGGAGCCTTGCTGTTTGGGGCCGGTGGGGCCGGTGGAGCCGGCGGGTCCAGCGGGATTGGCGGGTTCGCCGCGGGCGGGGCCGGTGGGCCCGGAGGGGCCGGTGGGCTGTTCAACGGCGGCGGGGCCGGCGGGGCCGGCGGGTCCGGCGTCAGCGGCGGGGCTGGCGGGGAGGGCGGGGCCGGCGGGGCCGGTGGCCTGTTCGCCGGTGGCGGGGCCGGCGGGGCCGGCGGATCGGGCAACAACGTCGGGGGGGCCGGCGGGGCCGGTGGGGTCGGTGGGCTGTTCGGGGCCGGCGGGGCCGGCGGATCCGGCGGCGGCGGTAGCGTTGCTGGCGACGGTGGGGCCGGCGGCAACGCGGGCTTGCTCGCCCCCGGTCTCGCCGGCGGTGCCGGCGGTGGCGGCGGGCAGGGTTTTGACACCGGCGGGGCCGGCGGGCCCGGCGGCGACGCCGGCCTGCTGGTCGGCTCCGGCGGGGTCGGAGGTGCCGGCGGATTCGGCCTCACTACGGGTGGGCCTGGGGCGGCCGGCGGCGACGCCGGCCTGCTGTTCGGCTCCGGCGGCGCTGGCGGGGCCGGCGGCTCCGGCCGAACCGACCTCGGCGGCGCTGGCGGGGCCGGCGGCAAGGCCGGGCTGATCGGCAACGGCGGTAACGGCGGGGCCGGCGGGGCCGGCGGGAACGGCGGCGGGGACGGCGGGCCCGGTGGAGCCGCCTTCGGGCTCGGTAACGGCGGCAACGGCGGCAACGGGGGGACCGGCACGTCCGCGGGCAGCCCCGGTGCCGGCGGCGCCGGTGG

>NC_018078|6|1|926467-927414|CRT
CGGCGGCGGAGGGACCGG	CGGGTCCGGCGTCAGCGGCGGGGCGGGCGGAGATGGCGGGGCCGGCGGGATCTTGTT
CGGCGCCGGCGGGGCCGG	CGGCGCGGGCGGGGCCGTCACGGGAACCGGCGCCACCGG
CGGGTCCGGTGGGGCCGG	CGGTGGAGCCTTGCTGTT
TGGGGCCGGTGGGGCCGG	TGGAGCCGGCGGGTCCAGCGGGATTGGCGGGTTCGCCGCGGG
CGGGGCCGGTGGGCCCGG	AGGGGCCGGTGGGCTGTTCAACGGCGG
CGGGGCCGGCGGGGCCGG	CGGGTCCGGCGTCAGCGGCGGGGCTGGCGGGGAGGG
CGGGGCCGGCGGGGCCGG	TGGCCTGTTCGCCGGTGG
CGGGGCCGGCGGGGCCGG	CGGATCGGGCAACAACGTCGG
GGGGGCCGGCGGGGCCGG	TGGGGTCGGTGGGCTGTT
CGGGGCCGGCGGGGCCGG	CGGATCCGGCGGCGGCGGTAGCGTTGC
TGGCGACGGTGGGGCCGG	CGGCAACGCGGGCTTGCTCGCCCCCGGTCTCGCCGGCGG
TGCCGGCGGTGGCGGCGG	GCAGGGTTTTGACACCGGCGG
GGCCGGCGGGCCCGGCGG	CGACGCCGGCCTGCTGGTCGGCTCCGGCGG
GGTCGGAGGTGCCGGCGG	ATTCGGCCTCACTACGGGTGGGCCTGGGGC
GGCCGGCGGCGACGCCGG	CCTGCTGTTCGGCTCCGGCGGCGCTGGCGG
GGCCGGCGGCTCCGGCCG	AACCGACCTCGGCGGCGCTGGCGG
GGCCGGCGGCAAGGCCGG	GCTGATCGGCAACGGCGGTAACGGCGGGGCCGGCGG
GGCCGGCGGGAACGGCGG	CGGGGACGGCGGGCCCGGTGGAGCCGCCTTCGGGCTCGG
TAACGGCGGCAACGGCGG	CAACGGGGGGACCGGCACGTCCGCGGGCAGCCCCGG
TGCCGGCGGCGCCGGTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003900633.1|935051_936131_-|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl|CDD|225449
NC_018078.1|WP_003898602.1|919480_920536_+|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|226188
NC_018078.1|WP_003899914.1|936818_938402_+|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
NC_018078.1|WP_009938276.1|921816_922722_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225852
NC_018078.1|WP_003404335.1|920587_920980_-|Ni(II)/Co(II)-sensing-metalloregulatory-transcriptional-repressor-KmtR	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NC_018078.1|WP_003404352.1|922740_923556_-|TIGR04255-family-protein	unknown	unknown	gnl|CDD|275082
NC_018078.1|WP_003898601.1|916323_917493_-|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl|CDD|129820
NC_018078.1|WP_003898600.1|914103_916158_-|LCP-family-protein	unknown	unknown	gnl|CDD|273029
NC_018078.1|WP_087902221.1|932093_933355_-|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_018078.1|WP_003404336.1|921037_921460_-|nucleoside-deaminase	unknown	unknown	gnl|CDD|223663
NC_018078.1|WP_003898607.1|931424_931976_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003899917.1|934096_934609_-|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl|CDD|236483
NC_018078.1|WP_009938275.1|918758_919400_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_018078.1|WP_003404362.1|930799_931444_+|sensor-domain-containing-protein	unknown	unknown	gnl|CDD|372884
NC_018078.1|WP_003900218.1|921421_921712_+|transposase	unknown	unknown	gnl|CDD|223747
NC_018078.1|WP_003404321.1|917580_918597_-|acyl-ACP-desaturase-DesA1	unknown	unknown	gnl|CDD|153109
NC_018078.1|WP_003899915.1|936279_936720_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003416149.1|934605_935001_-|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl|CDD|225065
NC_018078.1|WP_010886090.1|927683_930332_-|PE-family-protein	unknown	unknown	gnl|CDD|376422
NC_018078.1|WP_003899918.1|933828_934080_-|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl|CDD|340452

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_018078.1|WP_003404335.1|920587_920980_-|Ni(II)/Co(II)-sensing-metalloregulatory-transcriptional-repressor-KmtR	csa3	COG0640_csa3_CAS-I-A	4.4e-21	70.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003900633.1|935051_936131_-|GTP-3',8-cyclase-MoaA	gnl|CDD|225449	COG2896, MoaA, Molybdenum cofactor biosynthesis enzyme [Coenzyme metabolism].	2.21908e-144
NC_018078.1|WP_003898602.1|919480_920536_+|DUF2236-domain-containing-protein	gnl|CDD|226188	COG3662, COG3662, Uncharacterized protein conserved in bacteria [Function unknown].	7.60533e-137
NC_018078.1|WP_003899914.1|936818_938402_+|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.20664e-71
NC_018078.1|WP_009938276.1|921816_922722_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|225852	COG3315, COG3315, O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	3.5337e-95
NC_018078.1|WP_003404335.1|920587_920980_-|Ni(II)/Co(II)-sensing-metalloregulatory-transcriptional-repressor-KmtR	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	9.15024e-22
NC_018078.1|WP_003404352.1|922740_923556_-|TIGR04255-family-protein	gnl|CDD|275082	TIGR04255, hypothetical_protein, TIGR04255 family protein. Members of this uncharacterized protein family are found broadly but sporadically among bacteria and archaea, including members of the genera Mycobacterium, Nostoc, Acinetobacter, Planctomyces, Geobacter, Streptomyces, Methanospirillum, etc. The function is unknown.	1.96412e-45
NC_018078.1|WP_003898601.1|916323_917493_-|tRNA-dihydrouridine-synthase-DusB	gnl|CDD|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	7.36004e-168
NC_018078.1|WP_003898600.1|914103_916158_-|LCP-family-protein	gnl|CDD|273029	TIGR00350, Transcriptional_regulator_LytR, cell envelope-related function transcriptional attenuator common domain. This model describes a domain of unknown function that is found in the predicted extracellular domain of a number of putative membrane-bound proteins. One of these is proteins psr, described as a penicillin binding protein 5 (PDP-5) synthesis repressor. Another is Bacillus subtilis LytR, described as a transcriptional attenuator of itself and the LytABC operon, where LytC is N-acetylmuramoyl-L-alanine amidase. A third is CpsA, a putative regulatory protein involved in exocellular polysaccharide biosynthesis. Besides the region of strong similarily represented by this model, these proteins share the property of having a short putative N-terminal cytoplasmic domain and transmembrane domain forming a signal-anchor. [Regulatory functions, Other].	3.89123e-67
NC_018078.1|WP_087902221.1|932093_933355_-|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_018078.1|WP_003404336.1|921037_921460_-|nucleoside-deaminase	gnl|CDD|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	8.91868e-24
NC_018078.1|WP_003899917.1|934096_934609_-|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl|CDD|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	1.42282e-85
NC_018078.1|WP_009938275.1|918758_919400_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.99497e-07
NC_018078.1|WP_003404362.1|930799_931444_+|sensor-domain-containing-protein	gnl|CDD|372884	pfam14032, PknH_C, PknH-like extracellular domain. This domain is functionally uncharacterized. It is found as the periplasmic domain of the bacterial protein kinase PknH. The domain is also found in isolation in numerous proteins, for example the lipoproteins lpqQ, lprH, lppH and lpqA from M. tuberculosis. This family of proteins is found in bacteria. Proteins in this family are typically between 214 and 268 amino acids in length. There are two completely conserved C residues that are likely to form a disulphide bond. A second pair of cysteines are less well conserved probably form a second disulphide bond. It seems likely that this domain functions to bind some as yet unknown ligand.	1.2663e-18
NC_018078.1|WP_003900218.1|921421_921712_+|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.02344e-12
NC_018078.1|WP_003404321.1|917580_918597_-|acyl-ACP-desaturase-DesA1	gnl|CDD|153109	cd01050, Acyl_ACP_Desat, Acyl ACP desaturase, ferritin-like diiron-binding domain. Acyl-Acyl Carrier Protein Desaturase (Acyl_ACP_Desat) is a mu-oxo-bridged diiron-carboxylate enzyme, which belongs to a broad superfamily of ferritin-like proteins and catalyzes the NADPH and O2-dependent formation of a cis-double bond in acyl-ACPs. Acyl-ACP desaturases are found in higher plants and a few bacterial species (Mycobacterium tuberculosis, M. leprae, M. avium and Streptomyces avermitilis, S. coelicolor). In plants, Acyl-ACP desaturase is a plastid-localized, covalently ACP linked, soluble desaturase that introduces the first double bound into saturated fatty acids, resulting in the corresponding monounsaturated fatty acid. Members of this class of soluble desaturases are specific for a particular substrate chain length and introduce the double bond between specific carbon atoms. For example, delta 9 stearoyl-ACP is specific for stearic acid and introduces a double bond between carbon 9 and 10 to yield oleic acid in the ACP-bound form. The enzymatic reaction requires molecular oxygen, NAD(P)H, NAD(P)H ferredoxin oxido-reductase and ferredoxin. The enzyme is active in the homodimeric form; the monomer consists mainly of alpha-helices with the catalytic diiron center buried within a four-helix bundle. Integral membrane fatty acid desaturases that introduce double bonds into fatty acid chains, acyl-CoA desaturases of animals, yeasts, and fungi, and acyl-lipid desaturases of cyanobacteria and higher plants, are distinct from soluble acyl-ACP desaturases, lack diiron centers, and are not included in this CD.	1.08695e-140
NC_018078.1|WP_003416149.1|934605_935001_-|4a-hydroxytetrahydrobiopterin-dehydratase	gnl|CDD|225065	COG2154, COG2154, Pterin-4a-carbinolamine dehydratase [Coenzyme metabolism].	2.06174e-36
NC_018078.1|WP_010886090.1|927683_930332_-|PE-family-protein	gnl|CDD|376422	pfam00934, PE, PE family. This family named after a PE motif near to the amino terminus of the domain. The PE family of proteins all contain an amino-terminal region of about 110 amino acids. The carboxyl terminus of this family are variable and fall into several classes. The largest class of PE proteins is the highly repetitive PGRS class which have a high glycine content. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	5.97682e-28
NC_018078.1|WP_003899918.1|933828_934080_-|molybdopterin-converting-factor-subunit-1	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.6017e-22

Protein sequences

>NC_018078.1|WP_003404352.1|922740_923556_-|TIGR04255-family-protein
MLPETNQDEVQPNAPVALVTVEIRHPTTDSLTESANRELKHLLINDLPIERQAQDVSWGMTAPGGAPTPVADRFVRYVNRDNTTAASLKNQAIVVETTAYRSFEAFTDVVMRVVDARAQVSSIVGLERIGLRFVLEIRVPAGVDGRITWSNWIDEQLLGPQRFTPGGLVLTEWQGAAVYRELQPGKSLIVRYGPGMGQALDPNYHLRRITPAQTGPFFLLDIDSFWTPSGGSIPEYNRDALVSTFQDLYGPAQVVFQEMITSRLKDELLRQ
>NC_018078.1|WP_009938276.1|921816_922722_+|class-I-SAM-dependent-methyltransferase
MVRADRDRWDLVTSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAVGMDVYTRLVDWQIPVEGDSEFDPQRMATGMACRTRFFDQFFLDATHSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLGAEPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQDALFDNITALSAPGSRLAFEFVPDTAIFADERWRNYHNRMSELGFDIDLNELVYHGQRGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDDELATAFADLTYSSATLMR
>NC_018078.1|WP_003900218.1|921421_921712_+|transposase
MGPSSKTCHACRHVQDIGWDEKWQCDGCSITHQRDDNAAINLARYEEPPSVVGPVGAAVKRGADRKTGPGPAGGREARKGTGHPAGEQPRDGVLVA
>NC_018078.1|WP_003404336.1|921037_921460_-|nucleoside-deaminase
MPAGMAGFRRWAQTNDPTAHAESLAIRAACTKLGTEHLVGTTLNVLAHPCPMCYGSLYYCSPDEVVFLTSRDAYEPHYVDDRRYFEPATFYDEFAKEWQDRRLPMRQEHRPDIRAGAVDVYRFRQEPNGGERSAIAAPTG
>NC_018078.1|WP_003404335.1|920587_920980_-|Ni(II)/Co(II)-sensing-metalloregulatory-transcriptional-repressor-KmtR
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQHLAKLRMARLVRTRRDGTTIFYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSVAKASATKDVG
>NC_018078.1|WP_003898602.1|919480_920536_+|DUF2236-domain-containing-protein
MTQDTSATCPLTSTVQDSSPVAGQLGRPIGFRGLAGGCPVSPLGYESPPLPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFFRERWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKGVDGAGRRYHALNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQLFDEHVQWYRMYGMSMRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDLTELPKPPFAQRVPDWLWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLRRDEWLHRRFGDIVRLVFALVPFRFRKHPRARAGWDRATGRIPADAPLVQTPARNLPPPDERDNPTHYCPKV
>NC_018078.1|WP_009938275.1|918758_919400_-|TetR/AcrR-family-transcriptional-regulator
MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRHAGLRERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPREAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEWMPNFIELLQRKLSRIVDPVLQKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPAGPHN
>NC_018078.1|WP_003404321.1|917580_918597_-|acyl-ACP-desaturase-DesA1
MSAKLTDLQLLHELEPVVEKYLNRHLSMHKPWNPHDYIPWSDGKNYYALGGQDWDPDQSKLSDVAQVAMVQNLVTEDNLPSYHREIAMNMGMDGAWGQWVNRWTAEENRHGIALRDYLVVTRSVDPVELEKLRLEVVNRGFSPGQNHQGHYFAESLTDSVLYVSFQELATRISHRNTGKACNDPVADQLMAKISADENLHMIFYRDVSEAAFDLVPNQAMKSLHLILSHFQMPGFQVPEFRRKAVVIAVGGVYDPRIHLDEVVMPVLKKWRIFEREDFTGEGAKLRDELALVIKDLELACDKFEVSKQRQLDREARTGKKVSAHELHKTAGKLAMSRR
>NC_018078.1|WP_003898601.1|916323_917493_-|tRNA-dihydrouridine-synthase-DusB
MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRIGIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAFTGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFPAGSALRRALAMVKTFDELDCLLDRLDGTVPFPDSATGARGRQGSPARVALPDGWLTDPDDCRVPEGADAMGSGG
>NC_018078.1|WP_003898600.1|914103_916158_-|LCP-family-protein
MSDGESAAPWARLSESAFPDGVDRWITVPPATWVAAQGPRDTQNVGCHATGAVSVADLIARLGPAFPDLPTHRHVAPEPEPSGRGPKVHDDADDQQDTEAIAIPAHSLEFLSELPDLRAANYPRADHARREPELPGKQLTGSARVRPLRIRRTSPAPAKPAPNSGRRPMVLAARSLAALFAALALALTGGAWQWSASKNSRLNMVSALDPHSGDIVNPSGQHGDENFLLVGMDSRAGANANIGAGDAEDAGGARSDTVMLVNIPASRERVVAVSFPRDLAITPIQCEAWNPETGKYGPIYDEKTGTMGPRLVYTETKLNSAFSFGGPKCLVKVIQKLSGLSINRFIAIDFVGFARMVEALGGVEVCSTTPLRDYELGTVLEHAGRQVIDGPTALNYVRARQVTTESNGDYGRIKRQQLFLSSLLRSMISTDTLFNLSRLNNVVNMFIGNSYVDNVKTKDLVELGRSLQHMAAGHVTFVTVPTGITDQNGDEPPRTSDMKALFTAIIDDDPLPLENDHNAQRLGNTPSTPPTTTKKAPQAGLTNEIQHQQVTTTSPKEVTVQVSNSTGQAGLATTATDQLKRNGFNVMAPDDYPSSLLATTVFFSPGNEQAAATVAAVFGQSKIERVTGIGQLVQVVLGQDFSAVRAPLPSGSTVSVQISRNSSSPPTKLPEDLTVTNAADTTCE
>NC_018078.1|WP_010886090.1|927683_930332_-|PE-family-protein
MSFVIAAPDLVAMATEDLAGIGASLTAANAAAAVPTSGLLAAAGDEVSAAIAALFSSHGQQYQAMSAQAAAFHARFVQALAGAMGAYAAAEAANASPLQTLEQGLLGAINAPAAALSGRPFIGNGTNGAPGTGEAGGPGGWLLGNGGNGGSGAPGQTGGAGGAAGLLGHGGTGGAGGTGASGGKGGTGGWLWGSGGAGGAGGSGGGSGGAGGNALMFGIGGNGGAGGAASGVGNGGVGGAGGAGGALVAIGGAGGAGGAATTGTGGAGGAGSNALGLFLGLGGSGGQGGDSAMGSGGAGGAGGSGGAASPFGIDIGIGGAGGHGGAGTNGGAGGAGGAGGSSGTVFALDLSWGGAGGNGGAATTGTGGAGGTGGFAVAPDFIGFGAAYGGAGGLGGAATGAGGTGGTGGVGAGGFAALGVGVGGAGGAGGAATETGGIGGAGGLGVGLLGGAGGAGGPGGAASAGSGGHGGTGGDALGLIGAGIGGVGGVGGAATDTGGNGGAGGSGTGLLGGVGGAGGHGGGASVGTGGSGGAGGDGFGFVGAGGNGGNAGTGVGVNGANGGNGGSATGALAAVGGAGAAGGDATSGTGGFGGAGGSARGLIFALGGAGAAGGDASTGVGGPGGPGGTGTASSPFGIAIAIGGAGAQGGAGTSGATGGAGGDGVFEGIAVLGLGFGGAAGAGGAATGDGATGGAGGFGGAGAGIANFLGFSVLHGGAGGAGGTATGTGGNGGAGGGGGLSSPVILGIGIGGAGGDGGGALGVLGGMGGDGGDGGEAVAVGIAVGGAGGAGGAAPTGNGGAGGNGGDALGLVGVGGNGGNAGTGFGANTGGNGGDTTIVVNGMLAPSTLGYGGNGGNGVNGGAGGTGGKAGVFGAPGQNGLP
>NC_018078.1|WP_003404362.1|930799_931444_+|sensor-domain-containing-protein
MCCSTAAKSAVIVCCAAIATTACSFQATSTQPSTAPPTSRVDSLIVSIEDVRRIANYEELAAHFQTDLREPPEADTNVPGPCRVVGSSDRTFGTDWSEFRSAGYHGVTDDLRPGGPVMVETVSQAIALYPDPSTARGVFHRLESSLAECAGLHDPYFDFILDRPDASTVRIGAAGWSHVYRLKSSVFISVGVLGIEPAEPIANVILQTISDRIQ
>NC_018078.1|WP_003898607.1|931424_931976_-|hypothetical-protein
MKAATSWMQQQVLATATVVRWRLAWLSKPETWRRRKRRQSQKIRRSVQKQRRSTVWDNQRKTFGVVISPARLTAWIAASALILLTGTELFGTALSWVKLSPIWHVFSFAVDTRPIATLLDYASHPIDPRSYSSVAVTAVGAEATLLAFFFATVGVVASTALNTLRSSPPLLLSSPRLTTGCDR
>NC_018078.1|WP_087902221.1|932093_933355_-|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_018078.1|WP_003899918.1|933828_934080_-|molybdopterin-converting-factor-subunit-1
MIKVNVLYFGAVREACDETPREEVEVQNGTDVGNLVDQLQQKYPRLRDHCQRVQMAVNQFIAPLSTVLGDGDEVAFIPQVAGG
>NC_018078.1|WP_003899917.1|934096_934609_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MIDHALALTHIDERGAARMVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMAAARIAGIAAAKRTGDLIPLCHPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALTAVSVAALTIYDMCKAVDRAMEISQIVLQEKSGGRSGVYRRSASDLACQSR
>NC_018078.1|WP_003416149.1|934605_935001_-|4a-hydroxytetrahydrobiopterin-dehydratase
MTVSTPEQHEQRASHDASEGKHNVCQGRLAALADAAVSEKLGALPGWQLLDMRLSRAFQCTNFDQSIDFMNRVASIANDINHHPDIAVLDKRSVRVTAWTRKLGYLTDIDFDLAASVEAMYATEFADRPAR
>NC_018078.1|WP_003900633.1|935051_936131_-|GTP-3',8-cyclase-MoaA
MSTPTLPDMVAPSPRVRVKDRCRRMMGDLRLSVIDQCNLRCRYCMPEEHYTWLPRQDLLSVKEISAIVDVFLSVGVSKVRITGGEPLIRPDLPEIVRTLSAKVGEDSGLRDLAITTNGVLLADRVDGLKAAGMKRITVSLDTLQPERFKAISQRNSHDKVIAGIKAVAAAGFTDTKIDTTVMRGANHDELADLIEFARTVNAEVRFIEYMDVGGATHWAWEKVFTKANMLESLEKRYGRIEPLPKHDTAPANRYALPDGTTFGIIASTTEPFCATCDRSRLTADGLWLHCLYAISGINLREPLRAGATHDDLVETVTTGWRRRTDRGAEQRLAQRERGVFLPLSTLKADPHLEMHTRGG
>NC_018078.1|WP_003899915.1|936279_936720_-|hypothetical-protein
MTPNAASTGDSAKNTITGCCLITARALVARTRSISLPGMPFRMPADYHNASSDEPTNRHPWPAPARCCRHEWRTMRRTNACDRRRFGLSLTIHEDACRIISVVPVVLEVRRAEPAHPATPYPEPLARCSRSPGLNESSHMSGRIPP
>NC_018078.1|WP_003899914.1|936818_938402_+|FAD-binding-oxidoreductase
MRSWWGWGTVEDALSDQETQALQSRVAALVSGHDLSDHPPPDLTALGLAAPRVSPPASLAALCSSDLVDRAGHARGKAYRDIARNLQGQLDHLPDLIARPRSEQDVIDVLDWCAREGIAVIPYGGGSSVVGGVEPRFDEPVVTVDVTAMSAVLEIDRVSRAARIQAGAFGPSIEHQLRPHDLTLRHFPQSFGFSTLGGWLATRSGGHFATLYTHIDDLTESLRIVTPVGISESRRLPGSGAGPSPDRLFLGSEGTLGIITEAWMRLQHRPRWQVTVSVVFDDWAAAVAATRTIAQAGLYPANCRLLDPAEALLNAGTSVGGGLLVLAFESADHPIDPWLHRAVAITAEHGGTVTAQRSRGTTSDATEHNAAANWRSAFLRMPYQRDALVRRGVIAETFETACTWDGFDTLHAAVTDAARTAIWKVCGTGVVTCRFTHVYPDGPAPYYGIYAGGRWGSLDAQWDEIKAAVSEAISASGGTITHHHAVGRDHRAWYDRQRPDPFAAALRAAKSALDPAGILNPGVLLGR

Crispr_ID: NC_018078_7

• CRISPR_ID: NC_018078_7
• CRISPR_location: 1290372-1291939
• CRISPR_type: TypeIII
• Repeat_type: II-B,III-A
• Spacer_info: 21 spacers
• Cas_protein_info: cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6

Consensus repeat of NC_018078_7

Consensus_repeat	Method
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	PILER-CR
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CRISPRCasFinder
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CRT

spacers of NC_018078_7

>7.1|1290408|38|NC_018078|PILER-CR,CRISPRCasFinder,CRT
TTAAAACCGTGTTGCACTGCAACCCGGAATTCTTGCAC
>7.2|1290482|41|NC_018078|PILER-CR,CRISPRCasFinder,CRT
CATAGAGGGTCGCCGGCTCTGGATCACGCTCCCCTAGTCGT
>7.3|1290559|36|NC_018078|PILER-CR,CRISPRCasFinder,CRT
TTTTTGCCTCATGCTTGGGCGACAGCTTTTGACCAA
>7.4|1290631|34|NC_018078|PILER-CR,CRISPRCasFinder,CRT
TCGCAAGCGCCGTGCTTCCAGTGATCGCCTTCTA
>7.5|1290701|39|NC_018078|PILER-CR,CRISPRCasFinder,CRT
AACACCTCAGTAGCACGTCATACGCCGACCAATCATCAG
>7.6|1290776|35|NC_018078|PILER-CR,CRISPRCasFinder,CRT
TTTTCTGACCACTTGTGCGGGATTAGCGGGCTTAG
>7.7|1290847|37|NC_018078|PILER-CR,CRISPRCasFinder,CRT
ACCAATGCGTCGTCATTTCCGGCTTCAATTTCAGCCT
>7.8|1290920|38|NC_018078|PILER-CR,CRISPRCasFinder,CRT
CTGAGGAGAGCGAGTACTCGGGGCTGCCGTCTGCGCTG
>7.9|1290994|37|NC_018078|PILER-CR,CRISPRCasFinder,CRT
GCGTGAAACCGCCCCCAGCCTCGCCGGGGCCGCCTAG
>7.10|1291067|35|NC_018078|PILER-CR,CRISPRCasFinder,CRT
ACTCGGAATCCCATGTGCTGACAGCGGATTCGCAT
>7.11|1291138|37|NC_018078|PILER-CR,CRISPRCasFinder,CRT
CGGGCAGCGTTCGACACCCGCTCTAGTTGACTTCCGG
>7.12|1291211|41|NC_018078|PILER-CR,CRISPRCasFinder,CRT
CAGGTGAGCAACGGCGGCGGCAACCTGGCGGCCACGGGTCG
>7.13|1291288|40|NC_018078|PILER-CR,CRISPRCasFinder,CRT
ATGGGATATCTGCTGCCCGCCCGGGGAGATGCTGTCCGAG
>7.14|1291364|36|NC_018078|PILER-CR,CRISPRCasFinder,CRT
TTCGTCGACCATCATTGCCATTCCCTCTCCCCACGT
>7.15|1291436|41|NC_018078|PILER-CR,CRISPRCasFinder,CRT
TTGCGCCAACCCTTTCGGTGTGATGCGGATGGTCGGCTCGG
>7.16|1291513|29|NC_018078|PILER-CR
CTTGAATAACGCGCAGTGAATTTCGCGGA
>7.17|1291578|36|NC_018078|PILER-CR
ATTCGCACGAGTTCCCGTCAGCGTCGTAAATCGCCA
>7.18|1291650|37|NC_018078|PILER-CR
CCGGCAACAATCGCGCCGGCCCGCGCGGATGACTCCG
>7.19|1291723|36|NC_018078|PILER-CR
CGCATGGACCCGGGCGAGCTGCAGATGGTCCGGGAG
>7.20|1291795|36|NC_018078|PILER-CR
TGGATTGCGCTAACTGGCTTGGCGCTGATCCTGGTG
>7.21|1291867|41|NC_018078|PILER-CR
TCCACATCGATTTCCTTGACCTCGCCAGGAGAGAAGATCAC
>7.22|1291513|25|NC_018078|CRISPRCasFinder,CRT
CTTGAATAACGCGCAGTGAATTTCG
>7.23|1291574|36|NC_018078|CRISPRCasFinder,CRT
ATTCGCACGAGTTCCCGTCAGCGTCGTAAATCGCCA
>7.24|1291646|37|NC_018078|CRISPRCasFinder,CRT
CCGGCAACAATCGCGCCGGCCCGCGCGGATGACTCCG
>7.25|1291719|36|NC_018078|CRISPRCasFinder,CRT
CGCATGGACCCGGGCGAGCTGCAGATGGTCCGGGAG
>7.26|1291791|36|NC_018078|CRISPRCasFinder,CRT
TGGATTGCGCTAACTGGCTTGGCGCTGATCCTGGTG
>7.27|1291863|41|NC_018078|CRISPRCasFinder,CRT
TCCACATCGATTTCCTTGACCTCGCCAGGAGAGAAGATCAC

CRISPR arrays and Neighbor proteins around NC_018078_7

CRISPR arrays

The CRISPR arrays of NC_018078_7

>merge|NC_018078|7|1290372-1291939|PILER-CR,CRISPRCasFinder,CRT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTTAAAACCGTGTTGCACTGCAACCCGGAATTCTTGCACGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCATAGAGGGTCGCCGGCTCTGGATCACGCTCCCCTAGTCGTGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTTTTTGCCTCATGCTTGGGCGACAGCTTTTGACCAAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTCGCAAGCGCCGTGCTTCCAGTGATCGCCTTCTAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACAACACCTCAGTAGCACGTCATACGCCGACCAATCATCAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTTTTCTGACCACTTGTGCGGGATTAGCGGGCTTAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACACCAATGCGTCGTCATTTCCGGCTTCAATTTCAGCCTGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCTGAGGAGAGCGAGTACTCGGGGCTGCCGTCTGCGCTGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACGCGTGAAACCGCCCCCAGCCTCGCCGGGGCCGCCTAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACACTCGGAATCCCATGTGCTGACAGCGGATTCGCATGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCGGGCAGCGTTCGACACCCGCTCTAGTTGACTTCCGGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCAGGTGAGCAACGGCGGCGGCAACCTGGCGGCCACGGGTCGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACATGGGATATCTGCTGCCCGCCCGGGGAGATGCTGTCCGAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTTCGTCGACCATCATTGCCATTCCCTCTCCCCACGTGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTTGCGCCAACCCTTTCGGTGTGATGCGGATGGTCGGCTCGGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCTTGAATAACGCGCAGTGAATTTCGCGGATCAGACCCAAAACCCCGAGAGGGGACGGAAACATTCGCACGAGTTCCCGTCAGCGTCGTAAATCGCCAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCCGGCAACAATCGCGCCGGCCCGCGCGGATGACTCCGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCGCATGGACCCGGGCGAGCTGCAGATGGTCCGGGAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTGGATTGCGCTAACTGGCTTGGCGCTGATCCTGGTGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTCCACATCGATTTCCTTGACCTCGCCAGGAGAGAAGATCACGTCGTCAGACCCAAAACCCCGAGAGAGGACGGAAAC

>NC_018078|7|4|1290372-1291939|PILER-CR
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTAAAACCGTGTTGCACTGCAACCCGGAATTCTTGCAC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CATAGAGGGTCGCCGGCTCTGGATCACGCTCCCCTAGTCGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTTTGCCTCATGCTTGGGCGACAGCTTTTGACCAA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCGCAAGCGCCGTGCTTCCAGTGATCGCCTTCTA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	AACACCTCAGTAGCACGTCATACGCCGACCAATCATCAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTTCTGACCACTTGTGCGGGATTAGCGGGCTTAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACCAATGCGTCGTCATTTCCGGCTTCAATTTCAGCCT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTGAGGAGAGCGAGTACTCGGGGCTGCCGTCTGCGCTG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCGTGAAACCGCCCCCAGCCTCGCCGGGGCCGCCTAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACTCGGAATCCCATGTGCTGACAGCGGATTCGCAT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CGGGCAGCGTTCGACACCCGCTCTAGTTGACTTCCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CAGGTGAGCAACGGCGGCGGCAACCTGGCGGCCACGGGTCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATGGGATATCTGCTGCCCGCCCGGGGAGATGCTGTCCGAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTCGTCGACCATCATTGCCATTCCCTCTCCCCACGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTGCGCCAACCCTTTCGGTGTGATGCGGATGGTCGGCTCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTTGAATAACGCGCAGTGAATTTCGCGGA
TCAGACCCAAAACCCCGAGAGGGGACGGAAACATTC	GCACGAGTTCCCGTCAGCGTCGTAAATCGCCAGTCG
TCAGACCCAAAACCCCGAGAGGGGACGGAAACCCGG	CAACAATCGCGCCGGCCCGCGCGGATGACTCCGGTCG
TCAGACCCAAAACCCCGAGAGGGGACGGAAACCGCA	TGGACCCGGGCGAGCTGCAGATGGTCCGGGAGGTCG
TCAGACCCAAAACCCCGAGAGGGGACGGAAACTGGA	TTGCGCTAACTGGCTTGGCGCTGATCCTGGTGGTCG
TCAGACCCAAAACCCCGAGAGGGGACGGAAACTCCA	CATCGATTTCCTTGACCTCGCCAGGAGAGAAGATCACGTCG
TCAGACCCAAAACCCCGAGAGAGGACGGAAAC

>NC_018078|7|3|1290372-1291939|CRISPRCasFinder
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTAAAACCGTGTTGCACTGCAACCCGGAATTCTTGCAC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CATAGAGGGTCGCCGGCTCTGGATCACGCTCCCCTAGTCGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTTTGCCTCATGCTTGGGCGACAGCTTTTGACCAA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCGCAAGCGCCGTGCTTCCAGTGATCGCCTTCTA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	AACACCTCAGTAGCACGTCATACGCCGACCAATCATCAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTTCTGACCACTTGTGCGGGATTAGCGGGCTTAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACCAATGCGTCGTCATTTCCGGCTTCAATTTCAGCCT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTGAGGAGAGCGAGTACTCGGGGCTGCCGTCTGCGCTG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCGTGAAACCGCCCCCAGCCTCGCCGGGGCCGCCTAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACTCGGAATCCCATGTGCTGACAGCGGATTCGCAT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CGGGCAGCGTTCGACACCCGCTCTAGTTGACTTCCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CAGGTGAGCAACGGCGGCGGCAACCTGGCGGCCACGGGTCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATGGGATATCTGCTGCCCGCCCGGGGAGATGCTGTCCGAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTCGTCGACCATCATTGCCATTCCCTCTCCCCACGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTGCGCCAACCCTTTCGGTGTGATGCGGATGGTCGGCTCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTTGAATAACGCGCAGTGAATTTCG
CGGATCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATTCGCACGAGTTCCCGTCAGCGTCGTAAATCGCCA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCGGCAACAATCGCGCCGGCCCGCGCGGATGACTCCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CGCATGGACCCGGGCGAGCTGCAGATGGTCCGGGAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TGGATTGCGCTAACTGGCTTGGCGCTGATCCTGGTG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCCACATCGATTTCCTTGACCTCGCCAGGAGAGAAGATCAC
GTCGTCAGACCCAAAACCCCGAGAGAGGACGGAAAC

>NC_018078|7|2|1290372-1291939|CRT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTAAAACCGTGTTGCACTGCAACCCGGAATTCTTGCAC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CATAGAGGGTCGCCGGCTCTGGATCACGCTCCCCTAGTCGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTTTGCCTCATGCTTGGGCGACAGCTTTTGACCAA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCGCAAGCGCCGTGCTTCCAGTGATCGCCTTCTA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	AACACCTCAGTAGCACGTCATACGCCGACCAATCATCAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTTCTGACCACTTGTGCGGGATTAGCGGGCTTAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACCAATGCGTCGTCATTTCCGGCTTCAATTTCAGCCT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTGAGGAGAGCGAGTACTCGGGGCTGCCGTCTGCGCTG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCGTGAAACCGCCCCCAGCCTCGCCGGGGCCGCCTAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACTCGGAATCCCATGTGCTGACAGCGGATTCGCAT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CGGGCAGCGTTCGACACCCGCTCTAGTTGACTTCCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CAGGTGAGCAACGGCGGCGGCAACCTGGCGGCCACGGGTCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATGGGATATCTGCTGCCCGCCCGGGGAGATGCTGTCCGAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTCGTCGACCATCATTGCCATTCCCTCTCCCCACGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTGCGCCAACCCTTTCGGTGTGATGCGGATGGTCGGCTCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTTGAATAACGCGCAGTGAATTTCG
CGGATCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATTCGCACGAGTTCCCGTCAGCGTCGTAAATCGCCA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCGGCAACAATCGCGCCGGCCCGCGCGGATGACTCCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CGCATGGACCCGGGCGAGCTGCAGATGGTCCGGGAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TGGATTGCGCTAACTGGCTTGGCGCTGATCCTGGTG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCCACATCGATTTCCTTGACCTCGCCAGGAGAGAAGATCAC
GTCGTCAGACCCAAAACCCCGAGAGAGGACGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl|CDD|187811
NC_018078.1|WP_003913758.1|1280501_1281047_+|DUF1802-family-protein	unknown	unknown	gnl|CDD|226743
NC_018078.1|WP_003899488.1|1298956_1300111_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|272998
NC_018078.1|WP_087902221.1|1292015_1293277_+|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_018078.1|WP_003899489.1|1298465_1298723_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl|CDD|187830
NC_018078.1|WP_003414195.1|1297021_1297630_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_018078.1|WP_003917684.1|1301049_1301304_+|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|224483
NC_018078.1|WP_003414198.1|1295541_1296951_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_018078.1|WP_003414190.1|1298049_1298361_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003899491.1|1294732_1295545_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NC_018078.1|WP_003414184.1|1300309_1300501_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl|CDD|224251
NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|224262
NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl|CDD|273844
NC_018078.1|WP_009938577.1|1300497_1300902_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	1.3e-98	324.8	0.0
NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	6.2e-81	265.9	0.0
NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	1.9e-238	788.5	0.0
NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	1e-108	357.9	0.0
NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	9.8e-88	288.8	0.1
NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	3.7e-129	426.3	0.0
NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	6.8e-161	529.8	0.0
NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	5.6e-26	85.5	0.1
NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	2.1e-23	77.8	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NC_018078.1|WP_003913758.1|1280501_1281047_+|DUF1802-family-protein	gnl|CDD|226743	COG4293, COG4293, Uncharacterized protein conserved in bacteria [Function unknown].	1.13775e-85
NC_018078.1|WP_003899488.1|1298956_1300111_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.94329e-16
NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|272998	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1. This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.	2.72742e-113
NC_018078.1|WP_087902221.1|1292015_1293277_+|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6	gnl|CDD|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	0
NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.36536e-99
NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.37381e-109
NC_018078.1|WP_003414198.1|1295541_1296951_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.41102e-28
NC_018078.1|WP_003899491.1|1294732_1295545_-|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.94464e-110
NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.14295e-72
NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.40728e-139
NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	3.66595e-25
NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	4.56134e-21

Protein sequences

>NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
>NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
>NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6
MLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG
>NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNTYLKPFELTLRCLGPVFIGSGEKRTSKEYHVEGDRVYFPDMELLYADIPAHKRKSFEAFVMNTDGAQATAPLKEWVEPNAVKLDPAKHRGYEVKIGSIEPRRASRGRGGRMTRKKLTLNEIHAFIKDPLGRPYVPGSTVKGMLRSIYLQSLVHKRTAQPVRVPGHQTREHRQYGERFERKELRKSGRPNTRPQDAVNDLFQAIRVTDSPALRTSDLLICQKMDMNVHGKPDGLPLFRECLAPGTSISHRVVVDTSPTARGGWREGERFLETLAETAASVNQARYAEYRAMYPGVNAIVGPIVYLGGGAGYRSKTFVTDQDDMAKVLDAQFGKVVKHVDKTRELRVSPLVLKRTKIDNICYEMGQCELSIRRAE
>NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA
>NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
>NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2
MSVIQDDYVKQAEVIRGLPKKKNGFELTTTQLRVLLSLTAQLFDEAQQSANPTLPRQLKEKVQYLRVRFVYQSGREDAVKTFVRNAKLLEALEGIGDSRDGLLRFCRYMEALAAYKKYLDPKDK
>NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNPQLIEAIIGCLLHDIGKPVQRAALGYPGRHSAIGRAFMKKVWLRDSRNPSQFTDEVDEADIGVSDRRILDAISYHHSSALRTAAENGRLAADAPAYIAYIADNIAAGTDRRKADSDDGHGASTWDPDTPLYSMFNRFGSGTANLAFAPEMLDDRKPINIPSPRRIEFDKDRYAAIVNKLKAILVDLERSDTYLASLLNVLEATLSFVPSSTDASEVVDVSLFDHLKLTGALGACIWHYLQATGQSDFKSALFDKQDTFYNEKAFLLTTFDVSGIQDFIYTIHSSGAAKMLRARSFYLEMLTEHLIDELLARVGLSRANLNYSGGGHAYLLLPNTESARKSVEQFEREANDWLLENFATRLFIATGSVPLAANDLMRRPNESASQASNRALRYSGLYRELSEQLSAKKLARYSADQLRELNSRDHDGQKGDRECSVCHTVNRTVSADDEPKCSLCQALTAASSQIQSESRRFLLISDGATKGLPLPFGATLTFCSRADADKALQQPQTRRRYAKNKFFAGECLGTGLWVGDYVAQMEFGDYVKRASGIARLGVLRLDVDNLGQAFTHGFMEQGNGKFNTISRTAAFSRMLSLFFRQHINYVLARPKLRPITGDDPARPREATIIYSGGDDVFVVGAWDDVIEFGIELRERFHEFTQGKLTVSAGIGMFPDKYPISVMAREVGDLEDAAKSLPGKNGVALFDREFTFGWDELLSKVIEEKYRHIADYFSGNEERGMAFIYKLLELLAERDDRITKARWVYFLTRMRNPTGDTAPFQQFANRLHQWFQDPTDAKQLKTALHLYIYRTRKEESE
>NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6
MATLGPHLHGVLMESIPADYVQTLHTVPVNPYSQYALARSTTSLEWKISTLTNEARQQIVGPINDAAFAGFRLRASGIATQVTSRSLEQNPLSQFARIFYARPETRKFRVEFLTPTAFKQSGEYVFWPDPRLVFQSLAQKYGAIVDGEEPDPGLIAEFGQSVRLSAFRVASAPFAVGAARVPGFTGSATFTVRGVDTFASYIAALLWFGEFSGCGIKASMGMGAIRVQPLAPREKCVPKP
>NC_018078.1|WP_003913758.1|1280501_1281047_+|DUF1802-family-protein
MTPALKEWSAAVHALLDGRQTVLLRKGGIGEKRFEVAAHEFLLFPTVAHSHAERVRPEHRDLLGPAAADSTDECVLLRAAAKVVAALPVNRPEGLDAIEDLHIWTAESVRADRLDFRPKHKLAVLVVSAIPLAEPVRLARRPEYGGCTSWVQLPVTPTLAAPVHDEAALAEVAARVREAVG
>NC_018078.1|WP_087902221.1|1292015_1293277_+|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_018078.1|WP_003899491.1|1294732_1295545_-|AAA-family-ATPase
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NC_018078.1|WP_003414198.1|1295541_1296951_-|DDE-type-integrase/transposase/recombinase
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NC_018078.1|WP_003414195.1|1297021_1297630_-|hypothetical-protein
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NC_018078.1|WP_003414190.1|1298049_1298361_-|hypothetical-protein
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NC_018078.1|WP_003899489.1|1298465_1298723_-|hypothetical-protein
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NC_018078.1|WP_003899488.1|1298956_1300111_-|DDE-type-integrase/transposase/recombinase
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NC_018078.1|WP_003414184.1|1300309_1300501_-|hypothetical-protein
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NC_018078.1|WP_009938577.1|1300497_1300902_-|hypothetical-protein
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NC_018078.1|WP_003917684.1|1301049_1301304_+|hypothetical-protein
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA

Crispr_ID: NC_018078_8

• CRISPR_ID: NC_018078_8
• CRISPR_location: 1293304-1294584
• CRISPR_type: TypeIII
• Repeat_type: II-B,III-A
• Spacer_info: 17 spacers
• Cas_protein_info: cas2,cas1,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas6

Consensus repeat of NC_018078_8

Consensus_repeat	Method
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CRT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	PILER-CR
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CRISPRCasFinder

spacers of NC_018078_8

>8.1|1293340|35|NC_018078|CRT
TCGGGGAGCCGATCAGCGACCACCGCACCCTGTCA
>8.2|1293411|38|NC_018078|CRT,PILER-CR,CRISPRCasFinder
CTTCAGCACCACCATCATCCGGCGCCTCAGCTCAGCAT
>8.3|1293485|38|NC_018078|CRT,PILER-CR,CRISPRCasFinder
CCTTCGACGCCGGATTCGTGATCTCTTCCCGCGGATAG
>8.4|1293559|36|NC_018078|CRT,PILER-CR,CRISPRCasFinder
TGCCCCGGCGTTTAGCGATCACAACACCAACTAATG
>8.5|1293631|36|NC_018078|CRT,PILER-CR,CRISPRCasFinder
CAGCGAAATACAGGCTCCACGACACGACCACAACGC
>8.6|1293703|37|NC_018078|CRT,PILER-CR,CRISPRCasFinder
TCTTGACGATGCGGTTGCCCCGCGCCCTTTTCCAGCC
>8.7|1293776|37|NC_018078|CRT,PILER-CR,CRISPRCasFinder
AGGTTCGCGTCAGACAGGTTCGCGTCGATCAAGTCCG
>8.8|1293849|38|NC_018078|CRT,PILER-CR,CRISPRCasFinder
TTTATCACTCCCGACCAAATAGGTATCGGCGTGTTCAA
>8.9|1293923|37|NC_018078|CRT,PILER-CR,CRISPRCasFinder
ATTTTGAGCGCGAACTCGTCCACAGTCCCCCTTTCAG
>8.10|1293996|35|NC_018078|CRT,PILER-CR,CRISPRCasFinder
GCCCCGTGGATGGCGGATGCGTTGTGCGCGCAAGT
>8.11|1294067|40|NC_018078|CRT,PILER-CR,CRISPRCasFinder
CCGACGATGGCCAGTAAATCGGCGTGGGTAACCGATCCGG
>8.12|1294143|35|NC_018078|CRT,PILER-CR,CRISPRCasFinder
CTGACGGCACGGAGCTTTCCGGCTTCTATCAGGTA
>8.13|1294214|36|NC_018078|CRT,PILER-CR,CRISPRCasFinder
CCTCATGGTGGGACATGGACGAGCGCGACTATCGGG
>8.14|1294286|37|NC_018078|CRT,PILER-CR,CRISPRCasFinder
TGGACGCAGAATCGCACCGGGTGCGGGAGGTGCAGCA
>8.15|1294359|40|NC_018078|CRT,PILER-CR,CRISPRCasFinder
GCATATCGCCCGCCACACCACAGCCACGCTACTGCTCCAT
>8.16|1294435|40|NC_018078|CRT,PILER-CR,CRISPRCasFinder
ACACCGCCGATGACAGCTATGTCCGAGTGACATCCTCCCA
>8.17|1294511|38|NC_018078|CRT,PILER-CR,CRISPRCasFinder
TTGAACCGCCCTTCGCGCGGTGTTTCGGCCGTGCCCGA

CRISPR arrays and Neighbor proteins around NC_018078_8

CRISPR arrays

The CRISPR arrays of NC_018078_8

>merge|NC_018078|8|1293304-1294584|CRT,PILER-CR,CRISPRCasFinder
TCACCGGGGCGGTTCACCCCGAGAGGGGACGGAAACTCGGGGAGCCGATCAGCGACCACCGCACCCTGTCAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCTTCAGCACCACCATCATCCGGCGCCTCAGCTCAGCATGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCCTTCGACGCCGGATTCGTGATCTCTTCCCGCGGATAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTGCCCCGGCGTTTAGCGATCACAACACCAACTAATGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCAGCGAAATACAGGCTCCACGACACGACCACAACGCGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTCTTGACGATGCGGTTGCCCCGCGCCCTTTTCCAGCCGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACAGGTTCGCGTCAGACAGGTTCGCGTCGATCAAGTCCGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTTTATCACTCCCGACCAAATAGGTATCGGCGTGTTCAAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACATTTTGAGCGCGAACTCGTCCACAGTCCCCCTTTCAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACGCCCCGTGGATGGCGGATGCGTTGTGCGCGCAAGTGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCCGACGATGGCCAGTAAATCGGCGTGGGTAACCGATCCGGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCTGACGGCACGGAGCTTTCCGGCTTCTATCAGGTAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCCTCATGGTGGGACATGGACGAGCGCGACTATCGGGGTCGTCGGACCCAAAACCCCGAGAGGGGACGGAAACTGGACGCAGAATCGCACCGGGTGCGGGAGGTGCAGCAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACGCATATCGCCCGCCACACCACAGCCACGCTACTGCTCCATGTCCTCAGACCCAAAACCCCGAGAGGGGACGGAAACACACCGCCGATGACAGCTATGTCCGAGTGACATCCTCCCAGTCGTCAGACCCAAAACCACGAGAGGGGACGGAAACTTGAACCGCCCTTCGCGCGGTGTTTCGGCCGTGCCCGAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC

>NC_018078|8|3|1293304-1294584|CRT
TCACCGGGGCGGTTCACCCCGAGAGGGGACGGAAAC	TCGGGGAGCCGATCAGCGACCACCGCACCCTGTCA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTTCAGCACCACCATCATCCGGCGCCTCAGCTCAGCAT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCTTCGACGCCGGATTCGTGATCTCTTCCCGCGGATAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TGCCCCGGCGTTTAGCGATCACAACACCAACTAATG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CAGCGAAATACAGGCTCCACGACACGACCACAACGC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCTTGACGATGCGGTTGCCCCGCGCCCTTTTCCAGCC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	AGGTTCGCGTCAGACAGGTTCGCGTCGATCAAGTCCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTATCACTCCCGACCAAATAGGTATCGGCGTGTTCAA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATTTTGAGCGCGAACTCGTCCACAGTCCCCCTTTCAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCCCCGTGGATGGCGGATGCGTTGTGCGCGCAAGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCGACGATGGCCAGTAAATCGGCGTGGGTAACCGATCCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTGACGGCACGGAGCTTTCCGGCTTCTATCAGGTA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCTCATGGTGGGACATGGACGAGCGCGACTATCGGG
GTCGTCGGACCCAAAACCCCGAGAGGGGACGGAAAC	TGGACGCAGAATCGCACCGGGTGCGGGAGGTGCAGCA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCATATCGCCCGCCACACCACAGCCACGCTACTGCTCCAT
GTCCTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACACCGCCGATGACAGCTATGTCCGAGTGACATCCTCCCA
GTCGTCAGACCCAAAACCACGAGAGGGGACGGAAAC	TTGAACCGCCCTTCGCGCGGTGTTTCGGCCGTGCCCGA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC

>NC_018078|8|5|1293375-1294584|PILER-CR
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTTCAGCACCACCATCATCCGGCGCCTCAGCTCAGCAT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCTTCGACGCCGGATTCGTGATCTCTTCCCGCGGATAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TGCCCCGGCGTTTAGCGATCACAACACCAACTAATG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CAGCGAAATACAGGCTCCACGACACGACCACAACGC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCTTGACGATGCGGTTGCCCCGCGCCCTTTTCCAGCC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	AGGTTCGCGTCAGACAGGTTCGCGTCGATCAAGTCCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTATCACTCCCGACCAAATAGGTATCGGCGTGTTCAA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATTTTGAGCGCGAACTCGTCCACAGTCCCCCTTTCAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCCCCGTGGATGGCGGATGCGTTGTGCGCGCAAGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCGACGATGGCCAGTAAATCGGCGTGGGTAACCGATCCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTGACGGCACGGAGCTTTCCGGCTTCTATCAGGTA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCTCATGGTGGGACATGGACGAGCGCGACTATCGGG
GTCGTCGGACCCAAAACCCCGAGAGGGGACGGAAAC	TGGACGCAGAATCGCACCGGGTGCGGGAGGTGCAGCA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCATATCGCCCGCCACACCACAGCCACGCTACTGCTCCAT
GTCCTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACACCGCCGATGACAGCTATGTCCGAGTGACATCCTCCCA
GTCGTCAGACCCAAAACCACGAGAGGGGACGGAAAC	TTGAACCGCCCTTCGCGCGGTGTTTCGGCCGTGCCCGA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC

>NC_018078|8|4|1293375-1294584|CRISPRCasFinder
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTTCAGCACCACCATCATCCGGCGCCTCAGCTCAGCAT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCTTCGACGCCGGATTCGTGATCTCTTCCCGCGGATAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TGCCCCGGCGTTTAGCGATCACAACACCAACTAATG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CAGCGAAATACAGGCTCCACGACACGACCACAACGC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TCTTGACGATGCGGTTGCCCCGCGCCCTTTTCCAGCC
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	AGGTTCGCGTCAGACAGGTTCGCGTCGATCAAGTCCG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	TTTATCACTCCCGACCAAATAGGTATCGGCGTGTTCAA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ATTTTGAGCGCGAACTCGTCCACAGTCCCCCTTTCAG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCCCCGTGGATGGCGGATGCGTTGTGCGCGCAAGT
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCGACGATGGCCAGTAAATCGGCGTGGGTAACCGATCCGG
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CTGACGGCACGGAGCTTTCCGGCTTCTATCAGGTA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	CCTCATGGTGGGACATGGACGAGCGCGACTATCGGG
GTCGTCGGACCCAAAACCCCGAGAGGGGACGGAAAC	TGGACGCAGAATCGCACCGGGTGCGGGAGGTGCAGCA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	GCATATCGCCCGCCACACCACAGCCACGCTACTGCTCCAT
GTCCTCAGACCCAAAACCCCGAGAGGGGACGGAAAC	ACACCGCCGATGACAGCTATGTCCGAGTGACATCCTCCCA
GTCGTCAGACCCAAAACCACGAGAGGGGACGGAAAC	TTGAACCGCCCTTCGCGCGGTGTTTCGGCCGTGCCCGA
GTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003911993.1|1301479_1301755_-|DUF1778-domain-containing-protein	unknown	unknown	gnl|CDD|226860
NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	gnl|CDD|187811
NC_018078.1|WP_003414198.1|1295541_1296951_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_018078.1|WP_003899488.1|1298956_1300111_-|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234
NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|272998
NC_018078.1|WP_087902221.1|1292015_1293277_+|IS3-like-element-IS987-family-transposase	unknown	unknown	gnl|CDD|222853
NC_018078.1|WP_003899489.1|1298465_1298723_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	gnl|CDD|187830
NC_018078.1|WP_003414195.1|1297021_1297630_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_018078.1|WP_003917684.1|1301049_1301304_+|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|224483
NC_018078.1|WP_003414190.1|1298049_1298361_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003899491.1|1294732_1295545_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|225806
NC_018078.1|WP_003414184.1|1300309_1300501_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	gnl|CDD|227838
NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	gnl|CDD|224251
NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|224262
NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl|CDD|273844
NC_018078.1|WP_009938577.1|1300497_1300902_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	1.3e-98	324.8	0.0
NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	6.2e-81	265.9	0.0
NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	COG1353_cas10_CAS-III	1.9e-238	788.5	0.0
NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1	cas1	COG1518_cas1_CAS-I:CAS-II:CAS-III	1e-108	357.9	0.0
NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6	cas6	COG5551_cas6_CAS-III	9.8e-88	288.8	0.1
NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	COG1332_csm5gr7_CAS-III-A	3.7e-129	426.3	0.0
NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6	csm6	cd09699_csm6_CAS-III-A	6.8e-161	529.8	0.0
NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	5.6e-26	85.5	0.1
NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	2.1e-23	77.8	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003911993.1|1301479_1301755_-|DUF1778-domain-containing-protein	gnl|CDD|226860	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown].	1.95042e-26
NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
NC_018078.1|WP_003414198.1|1295541_1296951_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	7.41102e-28
NC_018078.1|WP_003899488.1|1298956_1300111_-|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.94329e-16
NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|272998	TIGR00287, CRISPR-associated_endonuclease_Cas1, CRISPR-associated endonuclease Cas1. This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.	2.72742e-113
NC_018078.1|WP_087902221.1|1292015_1293277_+|IS3-like-element-IS987-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.28492e-102
NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6	gnl|CDD|187830	cd09699, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems.	0
NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.36536e-99
NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.37381e-109
NC_018078.1|WP_003899491.1|1294732_1295545_-|AAA-family-ATPase	gnl|CDD|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	3.94464e-110
NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.14295e-72
NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.40728e-139
NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	3.66595e-25
NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	4.56134e-21

Protein sequences

>NC_018078.1|WP_087902221.1|1292015_1293277_+|IS3-like-element-IS987-family-transposase
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_018078.1|WP_003414276.1|1289981_1290323_+|CRISPR-associated-endonuclease-Cas2
MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
>NC_018078.1|WP_003414279.1|1288964_1289981_+|CRISPR-associated-endonuclease-Cas1
MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
>NC_018078.1|WP_003904058.1|1287803_1288952_+|type-III-A-CRISPR-associated-protein-Csm6
MLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG
>NC_018078.1|WP_003414285.1|1286580_1287708_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MNTYLKPFELTLRCLGPVFIGSGEKRTSKEYHVEGDRVYFPDMELLYADIPAHKRKSFEAFVMNTDGAQATAPLKEWVEPNAVKLDPAKHRGYEVKIGSIEPRRASRGRGGRMTRKKLTLNEIHAFIKDPLGRPYVPGSTVKGMLRSIYLQSLVHKRTAQPVRVPGHQTREHRQYGERFERKELRKSGRPNTRPQDAVNDLFQAIRVTDSPALRTSDLLICQKMDMNVHGKPDGLPLFRECLAPGTSISHRVVVDTSPTARGGWREGERFLETLAETAASVNQARYAEYRAMYPGVNAIVGPIVYLGGGAGYRSKTFVTDQDDMAKVLDAQFGKVVKHVDKTRELRVSPLVLKRTKIDNICYEMGQCELSIRRAE
>NC_018078.1|WP_003414288.1|1285675_1286584_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA
>NC_018078.1|WP_003414292.1|1284984_1285695_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
>NC_018078.1|WP_003414296.1|1284600_1284975_+|type-III-A-CRISPR-associated-protein-Csm2
MSVIQDDYVKQAEVIRGLPKKKNGFELTTTQLRVLLSLTAQLFDEAQQSANPTLPRQLKEKVQYLRVRFVYQSGREDAVKTFVRNAKLLEALEGIGDSRDGLLRFCRYMEALAAYKKYLDPKDK
>NC_018078.1|WP_003900580.1|1282165_1284604_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNPQLIEAIIGCLLHDIGKPVQRAALGYPGRHSAIGRAFMKKVWLRDSRNPSQFTDEVDEADIGVSDRRILDAISYHHSSALRTAAENGRLAADAPAYIAYIADNIAAGTDRRKADSDDGHGASTWDPDTPLYSMFNRFGSGTANLAFAPEMLDDRKPINIPSPRRIEFDKDRYAAIVNKLKAILVDLERSDTYLASLLNVLEATLSFVPSSTDASEVVDVSLFDHLKLTGALGACIWHYLQATGQSDFKSALFDKQDTFYNEKAFLLTTFDVSGIQDFIYTIHSSGAAKMLRARSFYLEMLTEHLIDELLARVGLSRANLNYSGGGHAYLLLPNTESARKSVEQFEREANDWLLENFATRLFIATGSVPLAANDLMRRPNESASQASNRALRYSGLYRELSEQLSAKKLARYSADQLRELNSRDHDGQKGDRECSVCHTVNRTVSADDEPKCSLCQALTAASSQIQSESRRFLLISDGATKGLPLPFGATLTFCSRADADKALQQPQTRRRYAKNKFFAGECLGTGLWVGDYVAQMEFGDYVKRASGIARLGVLRLDVDNLGQAFTHGFMEQGNGKFNTISRTAAFSRMLSLFFRQHINYVLARPKLRPITGDDPARPREATIIYSGGDDVFVVGAWDDVIEFGIELRERFHEFTQGKLTVSAGIGMFPDKYPISVMAREVGDLEDAAKSLPGKNGVALFDREFTFGWDELLSKVIEEKYRHIADYFSGNEERGMAFIYKLLELLAERDDRITKARWVYFLTRMRNPTGDTAPFQQFANRLHQWFQDPTDAKQLKTALHLYIYRTRKEESE
>NC_018078.1|WP_003912014.1|1281446_1282169_+|CRISPR-associated-endoribonuclease-Cas6
MATLGPHLHGVLMESIPADYVQTLHTVPVNPYSQYALARSTTSLEWKISTLTNEARQQIVGPINDAAFAGFRLRASGIATQVTSRSLEQNPLSQFARIFYARPETRKFRVEFLTPTAFKQSGEYVFWPDPRLVFQSLAQKYGAIVDGEEPDPGLIAEFGQSVRLSAFRVASAPFAVGAARVPGFTGSATFTVRGVDTFASYIAALLWFGEFSGCGIKASMGMGAIRVQPLAPREKCVPKP
>NC_018078.1|WP_003899491.1|1294732_1295545_-|AAA-family-ATPase
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NC_018078.1|WP_003414198.1|1295541_1296951_-|DDE-type-integrase/transposase/recombinase
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NC_018078.1|WP_003414195.1|1297021_1297630_-|hypothetical-protein
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NC_018078.1|WP_003414190.1|1298049_1298361_-|hypothetical-protein
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NC_018078.1|WP_003899489.1|1298465_1298723_-|hypothetical-protein
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NC_018078.1|WP_003899488.1|1298956_1300111_-|DDE-type-integrase/transposase/recombinase
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK
>NC_018078.1|WP_003414184.1|1300309_1300501_-|hypothetical-protein
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NC_018078.1|WP_009938577.1|1300497_1300902_-|hypothetical-protein
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NC_018078.1|WP_003917684.1|1301049_1301304_+|hypothetical-protein
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NC_018078.1|WP_003911993.1|1301479_1301755_-|DUF1778-domain-containing-protein
MPETLTGRLNFRLSPEQEQALRHAAALTGQSLSGFVLSAAVDHAHDLLARANRIELSEAAFRRFVAALDEPDEAAPELVRLARRKSRIPPH

Crispr_ID: NC_018078_9

• CRISPR_ID: NC_018078_9
• CRISPR_location: 2253921-2254062
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018078_9

Consensus_repeat	Method
TGAGTATTCCGTCGGTGACGGTTCCGCCGATCACGATTCCGGCTGGCAC	CRISPRCasFinder

spacers of NC_018078_9

>9.1|2253970|44|NC_018078|CRISPRCasFinder
GACACCAGCCAACATCACGGTAGGTGCGTTTAACTTGCCTCAGT

CRISPR arrays and Neighbor proteins around NC_018078_9

CRISPR arrays

The CRISPR arrays of NC_018078_9

>merge|NC_018078|9|2253921-2254062|CRISPRCasFinder
TTGATTTGCCGGGGTTGACGGTGCCGTCGTTGACGATTCCAGCTACAACGACACCAGCCAACATCACGGTAGGTGCGTTTAACTTGCCTCAGTTGAGTATTCCGTCGGTGACGGTTCCGCCGATCACGATTCCGGCTGGCAC

>NC_018078|9|5|2253921-2254062|CRISPRCasFinder
TTGATTTGCCGGGGTTGACGGTGCCGTCGTTGACGATTCCAGCTACAAC	GACACCAGCCAACATCACGGTAGGTGCGTTTAACTTGCCTCAGT
TGAGTATTCCGTCGGTGACGGTTCCGCCGATCACGATTCCGGCTGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003903680.1|2259978_2261175_-|isocitrate-lyase-subunit-AceAb	unknown	unknown	gnl|CDD|225134
NC_018078.1|WP_003900432.1|2250467_2251331_-|acyltransferase-family-protein	unknown	unknown	gnl|CDD|153249
NC_018078.1|WP_003899076.1|2266148_2266592_+|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NC_018078.1|WP_009937678.1|2266629_2268852_+|catalase/peroxidase-HPI	unknown	unknown	gnl|CDD|237891
NC_018078.1|WP_009938439.1|2246440_2247781_-|lipase-LipD	unknown	unknown	gnl|CDD|365903
NC_018078.1|WP_003899082.1|2251428_2251893_+|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176863
NC_018078.1|WP_003409667.1|2247771_2248887_-|serine-hydrolase	unknown	unknown	gnl|CDD|224594
NC_018078.1|WP_003409686.1|2241736_2242504_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|135631
NC_018078.1|WP_003409574.1|2262797_2263550_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293840
NC_018078.1|WP_003409666.1|2249158_2250430_+|hypothetical-protein	unknown	unknown	gnl|CDD|273654
NC_018078.1|WP_003409680.1|2244004_2245867_-|AMP-binding-protein	unknown	unknown	gnl|CDD|171527
NC_018078.1|WP_003906697.1|2261174_2262278_-|isocitrate-lyase-family-protein	unknown	unknown	gnl|CDD|225134
NC_018078.1|WP_003409684.1|2243517_2243997_+|immunoprotective-protein-Mpt63	unknown	unknown	gnl|CDD|370335
NC_018078.1|WP_072492204.1|2255642_2259809_+|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_018078.1|WP_003409685.1|2242507_2243281_-|YqjF-family-protein	unknown	unknown	gnl|CDD|225897
NC_018078.1|WP_003409566.1|2265441_2266035_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|224793
NC_018078.1|WP_003899079.1|2263649_2264654_+|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176236
NC_018078.1|WP_003409568.1|2264753_2265359_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl|CDD|224793
NC_018078.1|WP_003900434.1|2246023_2246404_+|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003409577.1|2262412_2262820_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003903680.1|2259978_2261175_-|isocitrate-lyase-subunit-AceAb	gnl|CDD|225134	COG2224, AceA, Isocitrate lyase [Energy production and conversion].	1.12063e-87
NC_018078.1|WP_003900432.1|2250467_2251331_-|acyltransferase-family-protein	gnl|CDD|153249	cd07987, LPLAT_MGAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.	3.35135e-64
NC_018078.1|WP_003899076.1|2266148_2266592_+|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	4.92282e-41
NC_018078.1|WP_009937678.1|2266629_2268852_+|catalase/peroxidase-HPI	gnl|CDD|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NC_018078.1|WP_009938439.1|2246440_2247781_-|lipase-LipD	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	5.65969e-52
NC_018078.1|WP_003899082.1|2251428_2251893_+|SRPBCC-family-protein	gnl|CDD|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	1.38133e-21
NC_018078.1|WP_003409667.1|2247771_2248887_-|serine-hydrolase	gnl|CDD|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	8.61879e-60
NC_018078.1|WP_003409686.1|2241736_2242504_+|SDR-family-oxidoreductase	gnl|CDD|135631	PRK05867, PRK05867, SDR family oxidoreductase.	8.21275e-152
NC_018078.1|WP_003409574.1|2262797_2263550_-|MBL-fold-metallo-hydrolase	gnl|CDD|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.95555e-42
NC_018078.1|WP_003409666.1|2249158_2250430_+|hypothetical-protein	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	4.7592e-11
NC_018078.1|WP_003409680.1|2244004_2245867_-|AMP-binding-protein	gnl|CDD|171527	PRK12476, PRK12476, putative fatty-acid--CoA ligase; Provisional.	0
NC_018078.1|WP_003906697.1|2261174_2262278_-|isocitrate-lyase-family-protein	gnl|CDD|225134	COG2224, AceA, Isocitrate lyase [Energy production and conversion].	1.00107e-132
NC_018078.1|WP_003409684.1|2243517_2243997_+|immunoprotective-protein-Mpt63	gnl|CDD|370335	pfam09167, DUF1942, Domain of unknown function (DUF1942). Members of this family of bacterial proteins assume a beta-sandwich structure consisting of two antiparallel beta-sheets similar to an immunoglobulin-like fold, with an additional small, antiparallel beta-sheet. The longer-stranded beta-sheet is made up of four antiparallel beta-strands. The shorter-stranded beta-sheet consists of five beta-strands, four of these beta-strands form an antiparallel beta-sheet. The exact function of this family of proteins is unknown, though a putative role includes involvement in host-bacterial interactions involved in endocytosis or phagocytosis, possibly during bacterial internalisation.	3.87872e-58
NC_018078.1|WP_072492204.1|2255642_2259809_+|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.39881e-80
NC_018078.1|WP_003409685.1|2242507_2243281_-|YqjF-family-protein	gnl|CDD|225897	COG3361, COG3361, Uncharacterized conserved protein [Function unknown].	4.52786e-127
NC_018078.1|WP_003409566.1|2265441_2266035_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	4.33831e-50
NC_018078.1|WP_003899079.1|2263649_2264654_+|zinc-binding-dehydrogenase	gnl|CDD|176236	cd08275, MDR3, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.26124e-152
NC_018078.1|WP_003409568.1|2264753_2265359_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl|CDD|224793	COG1881, COG1881, Phospholipid-binding protein [General function prediction only].	1.29998e-51

Protein sequences

>NC_018078.1|WP_003899082.1|2251428_2251893_+|SRPBCC-family-protein
MSGRKFSFEVTKTSSAPAATLFRLVTDGGNWATWAKPIVAQSSWARRGDPAPGGIGAIRKLGMWPVFVQEETVEYEQDRRHVYKLVGARTPVQDYFGEVVLTPNASGGTDLRWSGSFTEKVRGTGPVMRAALGGAVRFFAGQLVKAAEREAVRR
>NC_018078.1|WP_003900432.1|2250467_2251331_-|acyltransferase-family-protein
MFPRWPQQAHNHEVSRADTVSVPRAPTQAEVAAVLRIMTPLRKVIKPKVYGIENVPTERALLVGNHNTLGLVDAPLLAAELWERGRIVRSLGDHAHFKIPGWRDALTRTGVVEGTREITSELMRRGELVMVFPGGAREVNKRKNERYKLVWKNRLGFARLAIQHGYPIVPFASVGAEHGIDIVLDNESPLLAPVQFLAEKLLGTKDGPALVRGVGLTPVPRPERQYYWFGEPIDTTEFMGQQADDNAARRVRERAAAAIEHGIELMLAERAADPNRSLVGRLLRSDA
>NC_018078.1|WP_003409666.1|2249158_2250430_+|hypothetical-protein
MVRLIPSLLAMATVLGGVIGCSAHQPPTPASGCRQLDAFLKWHHGVREFLQSAIDANSRCTGTADGSARKVAIFDWDNTVVKNDIGYATNYYMLQHSLVLQPANQDWHAASRYLTDAAANALSVACGKVVPAGKPLPTGSNALCANEILSLLDGETTTGQPAFVGNNVRRLAGPYAWSNALSAGYTAEELAGFADQAKKQNLAADVGATQQVGTQQVDGYIRVYPQMKDLIGTLQAHGIDTWVVSASPEPIVKVWAGEVGLDDQHVVGVRSVADQSGKLTAHLVGCGGVRDGDDSVMTYLDGKRCWANQVIFGVTGPQAFNQLAADRRQVLAAGDSNSDATFVGDATVVSLVINRNQDDLMCRAYDGLFTRGGKWAINPMFIDPLPQHAPYVCGEAFINPDGSKQPVLRNDGTPIPDQVDSVF
>NC_018078.1|WP_003409667.1|2247771_2248887_-|serine-hydrolase
MDSTVTASIRRMLGLLAATLLLGGCTGQHTTRTAASTTYTPHIKASSQDVLDGAINADEPGCSAAVGVEGKVIWSGVRGIADLASGAKITTDTVFDIASVSKQFTATAILLLVEAGKLTLDDPISQYVPELPDWAQTVTVEQLMHQTSGIPDYVALLAARGYQVSDRTIEAEARQALAAAPELQFKPGTRFDYSNSNYLLLGEIVHRASGQPLPEFLSAEIFQPLGLAMVVDPVGKVPNKAVSYEKGTGGNRSEYRVGNPAWEQIGDGGIQTTPSQLARWADNYRTGSVGGLKLLEAQLAGAVETEPGGGDRYGAGIVSRADGTLDHAGAWAGFVTAFHISSDRRTSVAISCNTDKPDPVAMADALGRLWM
>NC_018078.1|WP_009938439.1|2246440_2247781_-|lipase-LipD
MDVAGLPRLAAGTQAAIIHGMAQPPSLLTTDNGLPFGVQGACDSRFTGVIRAFAGLYPGRKFGGGALSVYIDGRQVVDVWTGWSDRQGKVPWTADTGAMVFSATNGLAATVIHRLVDRGLLSYDAPVAEYWPEFGANGKSEVTVSDVLRHRSGLAHLKGVDKDEVMDHLLMEQKLAAAPLDRQHGKLAYHAVTYGWLLSGLARAVTGKGMRELFREELARPLNTDGIHLGRPPADSPTKAAQTLLPQAKVPTPLLDFIAPKVAGLSFSGLLGAVYFPGILSLLQDDMPFLDGEVPAVNGVVTARALAKTYGALANDGVIDGTRLLSSQAVRGLTGKSELWPDLNLGLPFTYHQGYQSSPVPGLLEGYGHIGLGGTIGWADPETGSAFGYVHNRLLTLLLFDIGSFAGLAALLNSAVVAARRDDPLEVPHFGAPYSEPRHEQAASGA
>NC_018078.1|WP_003900434.1|2246023_2246404_+|hypothetical-protein
MDPADVINPTSTRDAALARVLAYRQRVRARPLLIRATLAVVGGGLFVVSLPMIVLLPELGIPALLVAFRLLAVEAQWAVRAYAWTDWRFTQLREWFHRQVLVTRAAILVGLFLAAVALVWLLVYEF
>NC_018078.1|WP_003409680.1|2244004_2245867_-|AMP-binding-protein
MNDGSRQELRVRSGLLQIEDCLDADGGIALPAGTTLISLIERNIKYVGDLVAYRYLDHARSAAGCALEVTWTQFGMRLAAIGAHVQRFAGPGDRVAILAPQGIDYVCGFYAAIKAGTVAVPLFAPELPGHAERLDTALRDSEPAVILTTAAAKNAVEGFLNNVPRLRKPTVLVIDQIPDREGELFVPVELDIDAVSHLQYTSGSTRPPVGVEITHRAVGTNLVQMILSIDLLNRNTHGVSWLPLYHDMGLSMIGFPAVYGGHSTLMSPTAFVRRPLRWIQALSEGSRTGRVVTAAPNFAYEWAAQRGLPAQGDDVDLSNVVLIIGSEPVSIDAVTTFNKAFAPYGLPRTAFKPSYGIAEATLLVATIDHAAEPTVVYLDPEQLGAGHATRVAPDAPNAVVHVSCGHVARSLWAVIVDPDTGPEAGAELPDGEIGEVWLQGDNVARGYWGRPEETRMTFGARLQSPLAEGSHADGSAIDDTWLRTGDLGVYLDGELYITGRIADLLTIDGRNHYPQDIEATAAEASPMVRRGYITAFTVPASDGDDRNQRLVIIAERAAGTSRSDPRPALDAIRAAVCNRHGLSVADLSFLPAGAIPRTTSGKLARQACRAQYLSGRLGVH
>NC_018078.1|WP_003409684.1|2243517_2243997_+|immunoprotective-protein-Mpt63
MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIVAMNNGMEDLLIWEP
>NC_018078.1|WP_003409685.1|2242507_2243281_-|YqjF-family-protein
MTAIPGPSGAEPGESRALAGYPVTPPALPRPVIFDQRWTDLTFIHWPVLPESVAGSYPPGTRPDVFADGMTYVGLVPFRMSSTKLGTALPIPYVGTFPETNVRLYSIDNAGRHGVLFRSLETARLTVVPLTRIGLGIPYAWSRMRMMRSGKHITYHSVRRWPRRGLRSLLTITIGDLVEPTPLEVWLTARWGAHTRKAGRTWWVPNEHKPWPLRAAEIAELNDELIDASGVQPTGDRLRALFSPGVHARFGRPCVVQ
>NC_018078.1|WP_003409686.1|2241736_2242504_+|SDR-family-oxidoreductase
MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAIAARHLDALEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAELGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVNSVSPGYILTELVEPYTEYQPLWEPKIPLGRLGRPEELAGLYLYLASEASSYMTGSDIVIDGGYTCP
>NC_018078.1|WP_072492204.1|2255642_2259809_+|PPE-family-protein
MNFSTLPPEINSALIFGGAGSEPMSAAAVAWDQLAMELASAAASFNSVTSGLVGESWLGPSSAAMAAAVAPYLGWLAAAAAQAQRSATQAAALVAEFEAVRAAMVQPALVAANRSDLVSLVFSNFFGQNAPAIAAIEAAYEQMWAIDVSVMSAYHAGASAVASALTPFTAPPQNLTDLPAQLAAAPAAVVTAAITSSKGVLANLSLGLANSGFGQMGAANLGILNLGSLNPGGNNFGLGNVGSNNVGLGNTGNGNIGFGNTGNGNIGFGLTGDNQQGFGGWNSGTGNIGLFNSGTGNIGIGNTGTGNFGIGNSGTSYNTGIGNTGQANTGFFNAGIANTGIGNTGNYNTGSFNLGSFNTGDFNTGSSNTGFFNPGNLNTGVGNTGNVNTGGFNSGNYSNGFFWRGDYQGLIGFSGTLTIPAAGLDLNGLGSVGPITIPSITIPEIGLGINSSGALVGPINVPPITVPAIGLGINSTGALVGPINIPPITLNSIGLELSAFQVINVGSISIPASPLAIGLFGVNPTVGSIGPGSISIQLGTPEIPAIPPFFPGFPPDYVTVSGQIGPITFLSGGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGGLGPFTVFPDGYSLPAIPLGIDVGGAIGPLTTPPITIPAIPLGIDVSGSLGPINIPIEIAGTPGFGNSTTTPSSGFFNSGTGGTSGFGNVGSGGSGFWNIAGNLGNSGFLNVGPLTSGILNFGNTVSGLYNTSTLGLATSAFHSGVGNTDSQLAGFMRNAAGGTLFNFGFANDGTLNLGNANLGDYNVGSGNVGSYNFGSGNIGNGSFGFGNIGSNNFGFGNVGSNNLGFANTGPGLTEALHNIGFGNIGGNNYGFANIGNGNIGFGNTGTGNIGIGLTGDNQVGFGALNSGSGNIGFFNSGNGNIGFFNSGNGNVGIGNSGNYNTGLGNVGNANTGLFNTGNVNTGIGNAGSYNTGSYNAGDTNTGDLNPGNANTGYLNLGDLNTGWGNIGDLNTGALISGSYSNGILWRGDYQGLIGYSDTLSIPAIPLSVEVNGGIGPIVVPDITIPGIPLSLNALGGVGPIVVPDITIPGIPLSLNALGGVGPITVPGVPISRIPLTINIRIPVNITLNELPFNVAGIFTGYIGPIPLSTFVLGVTLAGGTLESGIQGFSVNPFGLNIPLSGATNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFAINPFGLDVPLSGGTNAVTIPGFAINPFGLNVPLSGGTSPVTIPGFTIPGSPLNLTANGGLGPINIPINITSAPGFGNSTTTPSSGFFNSGDGSASGFGNVGPGISGLWNQVPNALQGGVSGIYNVGQLASGVANLGNTVSGFNNTSTVGHLTAAFNSGVNNIGQMLLGFFSPGAGP
>NC_018078.1|WP_003903680.1|2259978_2261175_-|isocitrate-lyase-subunit-AceAb
MTYGEAVADVLEFGQSEGEPIGMAPEEWRAFAARASLHAARAKAKELGADPPWDCELAKTPEGYYQIRGGIPYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPDQMLAYNLSPSFNWDTTGMTDEEMRRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPRSDAALAASSGRTATTKAMGKGSTQHQHLVQTEVPRKLLEEWLAMWSGHYQLKDKLRVQLRPQRAGSEVLELGIHGESDDKLANVIFQPIQDRRGRTILLVRDQNTFGAELRQKRLMTLIHLWLVHRFKAQAVHYVTPTDDNLYQTSKMKSHGIFTEVNQEVGEIIVAEVNHPRIAELLTPDRVALRKLITKEA
>NC_018078.1|WP_003906697.1|2261174_2262278_-|isocitrate-lyase-family-protein
MAIAETDTEVHTPFEQDFEKDVAATQRYFDSSRFAGIIRLYTARQVVEQRGTIPVDHIVAREAAGAFYERLRELFAARKSITTFGPYSPGQAVSMKRMGIEAIYLGGWATSAKGSSTEDPGPDLASYPLSQVPDDAAVLVRALLTADRNQHYLRLQMSERQRAATPAYDFRPFIIADAGTGHGGDPHVRNLIRRFVEVGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATKLDVPSYKSCFLAMVRRFTNWASRSSMVIFSMRLATASTRRPAVGLSAKAFSAWSPTRSTRGGRTASSRSTAFSTRSSRGSWRPGRTTRA
>NC_018078.1|WP_003409577.1|2262412_2262820_+|hypothetical-protein
MVLSRTSTGRVILVPTQLRFDRWFLPLAVPLGLGPKNSELWVGAGSLHVKMGWAFAADIPLTSITKAEATNARVYAAGVHFGFGRWLVNGSRKGLVALTIDPPEQAKMWKKSMTVRELWVSVTDPDALVTACTAK
>NC_018078.1|WP_003409574.1|2262797_2263550_-|MBL-fold-metallo-hydrolase
MHFDWERLTDSVHRCRLPFCDVTVGLVRGRTGILLVDTGTTLGEATAIAADVKQIAGCQVTHVVLTHKHFDHVLGSSVFDQAEVFCAPEVVEYLRSATDRLREDALSYGADTAEVDRAIAALKPPQHGIYDAAVDLGDRTVTITHPGSGHTTADLVVVAPATGHADGPTVVFTGDLVEESADPDIDADSDLAAWPATLDRVLAIGGPDASYVPGHGKVVDAQFVRRQRAWLRTRASRQPRETPATLPCKR
>NC_018078.1|WP_003899079.1|2263649_2264654_+|zinc-binding-dehydrogenase
MRAVVITKHGDPSVLQVRQRPDPPPPGPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGGYCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAAVQFAKAAKAEVHGTASPQKHQKLAEFGVDRAIDYRRDGWWQGLGPYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVDKVVLVP
>NC_018078.1|WP_003409568.1|2264753_2265359_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MTSTLHRTPLATAGLALVVALGGCGGGGGDSRETPPYVPKATTVDATTPAPAAEPLTIASPMFADGAPIPVQFSCKGANVAPPLTWSSPAGAAELALVVDDPDAVGGLYVHWIVTGIAPGSGSTADGQTPAGGHSVPNSGGRQGYFGPCPPAGTGTHHYRFTLYHLPVALQLPPGATGVQAAQAIAQAASGQARLVGTFEG
>NC_018078.1|WP_003409566.1|2265441_2266035_+|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MAHAFHRFALAILGLALPVALVAYGGNGDSRKAAPLAPKAAALGRSMPETPTGDVLTISSPAFADGAPIPEQYTCKGANIAPPLTWSAPFGGALVVDDPDAPREPYVHWIVIGIAPGAGSTADGETPGGGISLPNSSGQPAYTGPCPPAGTGTHHYRFTLYHLPAVPPLAGLAGTQAARVIAQAATMQARLIGTYEG
>NC_018078.1|WP_003899076.1|2266148_2266592_+|transcriptional-repressor
MSSIPDYAEQLRTADLRVTRPRVAVLEAVNAHPHADTETIFGAVRFALPDVSRQAVYDVLHALTAAGLVRKIQPSGSVARYESRVGDNHHHIVCRSCGVIADVDCAVGEAPCLTASDHNGFLLDEAEVIYWGLCPDCSISDTSRSHP
>NC_018078.1|WP_009937678.1|2266629_2268852_+|catalase/peroxidase-HPI
MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDIEEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLSWADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPDPMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITTGIEVVWTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEHPEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQIRASGLTVSQLVSTAWAAASSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAGHNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKRLPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKFVQDFVAAWDKVMNLDRFDVR

Crispr_ID: NC_018078_10

• CRISPR_ID: NC_018078_10
• CRISPR_location: 2360497-2361537
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 17 spacers

Consensus repeat of NC_018078_10

Consensus_repeat	Method
NNCGGCGGNGCCGGCGGN	CRT

spacers of NC_018078_10

>10.1|2360515|54|NC_018078|CRT
TCCGGCGCGGCCGGCATGCCCGGGGGCAACGGCGGAGCCGCTGGCCTGTTCGGC
>10.2|2360587|33|NC_018078|CRT
GCCGGGGGGAACGTAGCGTCCGGCACCGCAGGG
>10.3|2360638|21|NC_018078|CRT
GCCGGCGGGCTGCTCTACGGC
>10.4|2360677|42|NC_018078|CRT
GCCGGCGGACGCGCCGGTGGTGGGGTGGGCGGTATTGGTGGG
>10.5|2360737|21|NC_018078|CRT
AATGGCGGGCTGCTGTTCGGC
>10.6|2360776|27|NC_018078|CRT
GTCGGCGGACTCGCGGCTGACGCCGGT
>10.7|2360821|30|NC_018078|CRT
GACGGCGGGTTGTTCTTCGGCGTGGGCGGT
>10.8|2360869|24|NC_018078|CRT
ACCGGCACTAATGTCACCGGCGGT
>10.9|2360911|21|NC_018078|CRT
AATGGCGGGCTCCTGTTCGGC
>10.10|2360950|36|NC_018078|CRT
GTTGGCGGTGACGGTGTGGCATTCCTGGGCACCGCC
>10.11|2361004|36|NC_018078|CRT
GCCGGCGGGGCCGGTGGGCTGTTCGGCGTCGGTGGG
>10.12|2361058|60|NC_018078|CRT
ATCGGATTGGTCGGGAACGGCGGTGCCGGGGGGTCCGGCGGGTCCGCCCTGCTCTGGGGC
>10.13|2361136|69|NC_018078|CRT
GCGGGTGGGGTCGGGTCCACTACCGGCGGTGCCGGCGGGGCGGGCGGCAACGCCGGCCTGCTGGTAGGC
>10.14|2361223|78|NC_018078|CRT
GCCGGCGCACTCGGCGGTGGCGCTACCGGGGTGGGCGGCGCCGGCGGAAACGGCGGCACTGCGGGCCTGCTGTTTGGT
>10.15|2361319|69|NC_018078|CRT
TTCGGCTTCGGCGGTGCCGGGGGCGCCGGTGGGCTCGGCGGCAAAGCCGGGCTGATCGGCGACGGCGGT
>10.16|2361406|60|NC_018078|CRT
AACGGCACCGGTGCCAAGGGCGGTGACGGCGGCGCTGGCGGCGGTGCCATCCTGGTCGGC
>10.17|2361484|36|NC_018078|CRT
AACGCCGGGAGTGGCACACCTAACGGCAGCGCGGGC

CRISPR arrays and Neighbor proteins around NC_018078_10

CRISPR arrays

The CRISPR arrays of NC_018078_10

>merge|NC_018078|10|2360497-2361537|CRT
AACGGCGGGGCCGGCGGCTCCGGCGCGGCCGGCATGCCCGGGGGCAACGGCGGAGCCGCTGGCCTGTTCGGCAACGGCGGGGCCGGCGGCGCCGGGGGGAACGTAGCGTCCGGCACCGCAGGGTTCGGCGGGGCCGGCGGGGCCGGCGGGCTGCTCTACGGCGCCGGCGGGGCCGGCGGCGCCGGCGGACGCGCCGGTGGTGGGGTGGGCGGTATTGGTGGGGCCGGCGGGGCCGGCGGCAATGGCGGGCTGCTGTTCGGCGCCGGCGGGGCCGGCGGCGTCGGCGGACTCGCGGCTGACGCCGGTGACGGCGGGGCCGGCGGAGACGGCGGGTTGTTCTTCGGCGTGGGCGGTGCCGGCGGGGCCGGCGGCACCGGCACTAATGTCACCGGCGGTGCCGGCGGGGCCGGCGGCAATGGCGGGCTCCTGTTCGGCGCCGGCGGGGTGGGCGGTGTTGGCGGTGACGGTGTGGCATTCCTGGGCACCGCCCCCGGCGGGCCCGGTGGTGCCGGCGGGGCCGGTGGGCTGTTCGGCGTCGGTGGGGCCGGCGGCGCCGGCGGAATCGGATTGGTCGGGAACGGCGGTGCCGGGGGGTCCGGCGGGTCCGCCCTGCTCTGGGGCGACGGCGGTGCCGGCGGCGCGGGTGGGGTCGGGTCCACTACCGGCGGTGCCGGCGGGGCGGGCGGCAACGCCGGCCTGCTGGTAGGCGCCGGCGGGGCCGGCGGCGCCGGCGCACTCGGCGGTGGCGCTACCGGGGTGGGCGGCGCCGGCGGAAACGGCGGCACTGCGGGCCTGCTGTTTGGTGCCGGCGGCGCCGGCGGATTCGGCTTCGGCGGTGCCGGGGGCGCCGGTGGGCTCGGCGGCAAAGCCGGGCTGATCGGCGACGGCGGTGACGGCGGCGCCGGAGGAAACGGCACCGGTGCCAAGGGCGGTGACGGCGGCGCTGGCGGCGGTGCCATCCTGGTCGGCAACGGCGGCAACGGCGGCAACGCCGGGAGTGGCACACCTAACGGCAGCGCGGGCACCGGCGGTGCCGGCGGG

>NC_018078|10|4|2360497-2361537|CRT
AACGGCGGGGCCGGCGGC	TCCGGCGCGGCCGGCATGCCCGGGGGCAACGGCGGAGCCGCTGGCCTGTTCGGC
AACGGCGGGGCCGGCGGC	GCCGGGGGGAACGTAGCGTCCGGCACCGCAGGG
TTCGGCGGGGCCGGCGGG	GCCGGCGGGCTGCTCTACGGC
GCCGGCGGGGCCGGCGGC	GCCGGCGGACGCGCCGGTGGTGGGGTGGGCGGTATTGGTGGG
GCCGGCGGGGCCGGCGGC	AATGGCGGGCTGCTGTTCGGC
GCCGGCGGGGCCGGCGGC	GTCGGCGGACTCGCGGCTGACGCCGGT
GACGGCGGGGCCGGCGGA	GACGGCGGGTTGTTCTTCGGCGTGGGCGGT
GCCGGCGGGGCCGGCGGC	ACCGGCACTAATGTCACCGGCGGT
GCCGGCGGGGCCGGCGGC	AATGGCGGGCTCCTGTTCGGC
GCCGGCGGGGTGGGCGGT	GTTGGCGGTGACGGTGTGGCATTCCTGGGCACCGCC
CCCGGCGGGCCCGGTGGT	GCCGGCGGGGCCGGTGGGCTGTTCGGCGTCGGTGGG
GCCGGCGGCGCCGGCGGA	ATCGGATTGGTCGGGAACGGCGGTGCCGGGGGGTCCGGCGGGTCCGCCCTGCTCTGGGGC
GACGGCGGTGCCGGCGGC	GCGGGTGGGGTCGGGTCCACTACCGGCGGTGCCGGCGGGGCGGGCGGCAACGCCGGCCTGCTGGTAGGC
GCCGGCGGGGCCGGCGGC	GCCGGCGCACTCGGCGGTGGCGCTACCGGGGTGGGCGGCGCCGGCGGAAACGGCGGCACTGCGGGCCTGCTGTTTGGT
GCCGGCGGCGCCGGCGGA	TTCGGCTTCGGCGGTGCCGGGGGCGCCGGTGGGCTCGGCGGCAAAGCCGGGCTGATCGGCGACGGCGGT
GACGGCGGCGCCGGAGGA	AACGGCACCGGTGCCAAGGGCGGTGACGGCGGCGCTGGCGGCGGTGCCATCCTGGTCGGC
AACGGCGGCAACGGCGGC	AACGCCGGGAGTGGCACACCTAACGGCAGCGCGGGC
ACCGGCGGTGCCGGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003899041.1|2349666_2350155_-|glycogen-accumulation-regulator-GarA	unknown	unknown	gnl|CDD|224630
NC_018078.1|WP_003409239.1|2348926_2349670_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133378
NC_018078.1|WP_003409199.1|2366638_2367070_+|DUF4189-domain-containing-protein	unknown	unknown	gnl|CDD|372741
NC_018078.1|WP_003906680.1|2371600_2372830_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_018078.1|WP_003901259.1|2365327_2366230_-|sterol-desaturase-family-protein	unknown	unknown	gnl|CDD|225546
NC_018078.1|WP_003409204.1|2364557_2365223_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003409227.1|2353041_2353671_-|CDP-alcohol-phosphatidyltransferase-family-protein	unknown	unknown	gnl|CDD|223632
NC_018078.1|WP_003409193.1|2367391_2368594_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224172
NC_018078.1|WP_003409231.1|2351731_2352064_-|DUF1290-domain-containing-protein	unknown	unknown	gnl|CDD|226374
NC_018078.1|WP_009939428.1|2350836_2351715_-|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|226396
NC_018078.1|WP_003899030.1|2370062_2371469_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_018078.1|WP_003899040.1|2350394_2350799_-|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl|CDD|234918
NC_018078.1|WP_003900416.1|2358022_2359942_+|vitamin-B12-ABC-transporter-ATP-binding-protein-BacA	unknown	unknown	gnl|CDD|226646
NC_018078.1|WP_003911668.1|2353867_2356204_-|accessory-Sec-system-translocase-SecA2	unknown	unknown	gnl|CDD|237060
NC_018078.1|WP_003899032.1|2368603_2369308_-|MgtC/SapB-family-protein	unknown	unknown	gnl|CDD|224204
NC_018078.1|WP_003409188.1|2369461_2369818_-|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NC_018078.1|WP_003409205.1|2363790_2364495_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379115
NC_018078.1|WP_003409218.1|2356308_2357952_-|acetolactate-synthase	unknown	unknown	gnl|CDD|235629
NC_018078.1|WP_003901262.1|2352125_2353049_-|DUF881-domain-containing-protein	unknown	unknown	gnl|CDD|226396
NC_018078.1|WP_003409207.1|2361692_2363156_-|FAD-binding-protein	unknown	unknown	gnl|CDD|180854

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003899041.1|2349666_2350155_-|glycogen-accumulation-regulator-GarA	gnl|CDD|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	3.81746e-35
NC_018078.1|WP_003409239.1|2348926_2349670_-|MerR-family-transcriptional-regulator	gnl|CDD|133378	cd00592, HTH_MerR-like, Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators. Helix-turn-helix (HTH) MerR-like transcription regulator, N-terminal domain. The MerR family transcription regulators have been shown to mediate responses to stress including exposure to heavy metals, drugs, or oxygen radicals in eubacterial and some archaeal species. They regulate transcription of multidrug/metal ion transporter genes and oxidative stress regulons by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.6505e-17
NC_018078.1|WP_003409199.1|2366638_2367070_+|DUF4189-domain-containing-protein	gnl|CDD|372741	pfam13827, DUF4189, Domain of unknown function (DUF4189). This domain of unknown function contains six well-conserved cysteine residues.	4.20219e-12
NC_018078.1|WP_003906680.1|2371600_2372830_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	9.20919e-57
NC_018078.1|WP_003901259.1|2365327_2366230_-|sterol-desaturase-family-protein	gnl|CDD|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	1.47599e-56
NC_018078.1|WP_003409227.1|2353041_2353671_-|CDP-alcohol-phosphatidyltransferase-family-protein	gnl|CDD|223632	COG0558, PgsA, Phosphatidylglycerophosphate synthase [Lipid metabolism].	2.43578e-28
NC_018078.1|WP_003409193.1|2367391_2368594_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	3.92596e-115
NC_018078.1|WP_003409231.1|2351731_2352064_-|DUF1290-domain-containing-protein	gnl|CDD|226374	COG3856, Sbp, Uncharacterized conserved protein (small basic protein) [Function unknown].	1.24966e-42
NC_018078.1|WP_009939428.1|2350836_2351715_-|DUF881-domain-containing-protein	gnl|CDD|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	2.67725e-79
NC_018078.1|WP_003899030.1|2370062_2371469_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	3.25979e-58
NC_018078.1|WP_003899040.1|2350394_2350799_-|glycine-cleavage-system-protein-GcvH	gnl|CDD|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.57956e-64
NC_018078.1|WP_003900416.1|2358022_2359942_+|vitamin-B12-ABC-transporter-ATP-binding-protein-BacA	gnl|CDD|226646	COG4178, COG4178, ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only].	0
NC_018078.1|WP_003911668.1|2353867_2356204_-|accessory-Sec-system-translocase-SecA2	gnl|CDD|237060	PRK12326, PRK12326, preprotein translocase subunit SecA; Reviewed.	0
NC_018078.1|WP_003899032.1|2368603_2369308_-|MgtC/SapB-family-protein	gnl|CDD|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	7.54596e-69
NC_018078.1|WP_003409188.1|2369461_2369818_-|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	2.00134e-24
NC_018078.1|WP_003409205.1|2363790_2364495_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.04829e-11
NC_018078.1|WP_003409218.1|2356308_2357952_-|acetolactate-synthase	gnl|CDD|235629	PRK05858, PRK05858, acetolactate synthase.	0
NC_018078.1|WP_003901262.1|2352125_2353049_-|DUF881-domain-containing-protein	gnl|CDD|226396	COG3879, COG3879, Uncharacterized protein conserved in bacteria [Function unknown].	2.39339e-84
NC_018078.1|WP_003409207.1|2361692_2363156_-|FAD-binding-protein	gnl|CDD|180854	PRK07121, PRK07121, FAD-binding protein.	0

Protein sequences

>NC_018078.1|WP_003900416.1|2358022_2359942_+|vitamin-B12-ABC-transporter-ATP-binding-protein-BacA
MGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVLAVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHLTQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLNIFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPVIDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRLHGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYASGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVAFARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV
>NC_018078.1|WP_003409218.1|2356308_2357952_-|acetolactate-synthase
MSTDTAPAQTMHAGRLIARRLKASGIDTVFTLSGGHLFSIYDGCREEGIRLIDTRHEQTAAFAAEGWSKVTRVPGVAALTAGPGITNGMSAMAAAQQNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVARFAATAQSAENAGLLVDQALQAAVSAPSGVAFVDFPMDHAFSMSSDNGRPGALTELPAGPTPAGDALDRAAGLLSTAQRPVIMAGTNVWWGHAEAALLRLVEERHIPVLMNGMARGVVPADHRLAFSRARSKALGEADVALIVGVPMDFRLGFGGVFGSTTQLIVADRVEPAREHPRPVAAGLYGDLTATLSALAGSGGTDHQGWIEELATAETMARDLEKAELVDDRIPLHPMRVYAELAALLERDALVVIDAGDFGSYAGRMIDSYLPGCWLDSGPFGCLGSGPGYALAAKLARPQRQVVLLQGDGAFGFSGMEWDTLVRHNVAVVSVIGNNGIWGLEKHPMEALYGYSVVAELRPGTRYDEVVRALGGHGELVSVPAELRPALERAFASGLPAVVNVLTDPSVAYPRRSNLA
>NC_018078.1|WP_003911668.1|2353867_2356204_-|accessory-Sec-system-translocase-SecA2
MPKTTRAQPGRLSSRFWRLLGASTEKNRSRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESADIPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTPDERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRNVHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRVYITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAANLDHNKLPMATDENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVSEERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSALSLPGVFR
>NC_018078.1|WP_003409227.1|2353041_2353671_-|CDP-alcohol-phosphatidyltransferase-family-protein
MEPVLTQNRVLTVPNMLSVIRLALIPAFVYVVLSAHANGWGVAILVFSGVSDWADGKIARLLNQSSRLGALLDPAVDRLYMVTVPIVFGLSGIVPWWFVLTLLTRDALLAGTLPLLWSRGLSALPVTYVGKAATFGFMVGFPTILLGQCDPLWSHVLLACGWAFLIWGMYAYLWAFVLYAVQMTMVVRQMPKLKGRAHRPAAQNAGERG
>NC_018078.1|WP_003901262.1|2352125_2353049_-|DUF881-domain-containing-protein
MAESDRLLGGYDPNAGYSAHAGAQPQRIPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWMWQALAATLVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSAKVDDVRRIVLADDAEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGASPNLSDVSKQRVSGSQQIILDRDLQLVVNSLWESGAEAISIDGVRIGPNVTIRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSYGVGVSVNVGDGLALPAGATRDVKFAKQIGP
>NC_018078.1|WP_003409231.1|2351731_2352064_-|DUF1290-domain-containing-protein
MIGIAALAVGIVLGLVFHPGVPEVIQPYLPIAVVAALDAVFGGLRAYLERIFDPKVFVVSFVFNVLVAALIVYVGDQLGVGTQLSTAIIVVLGIRIFGNTAALRRRLFGA
>NC_018078.1|WP_009939428.1|2350836_2351715_-|DUF881-domain-containing-protein
MSENRPEPVAAETSAATTARHSQADAGAHDAVRRGRHELPADHPRSKVGPLRRTRLTEILRGGRSRLVFGTLAILLCLVLGVAIVTQVRQTDSGDSLETARPADLLVLLDSLRQREATLNAEVIDLQNTLNALQASGNTDQAALESAQARLAALSILVGAVGATGPGVMITIDDPGPGVASEVMIDVINELRAAGAEAIQINDAHRSVRVGVDTWVVGVPGSLTVDTKVLSPPYSILAIGDPPTLAAAMNIPGGAQDGVKRVGGRMVVQQADRVDVTALRQPKQHQYAQPVK
>NC_018078.1|WP_003899040.1|2350394_2350799_-|glycine-cleavage-system-protein-GcvH
MSDIPSDLHYTAEHEWIRRSGDDTVRVGITDYAQSALGDVVFVQLPVIGTAVTAGETFGEVESTKSVSDLYAPISGKVSEVNSDLDGTPQLVNSDPYGAGWLLDIQVDSSDVAALESALTTLLDAEAYRGTLTE
>NC_018078.1|WP_003899041.1|2349666_2350155_-|glycogen-accumulation-regulator-GarA
MTDMNPDIEKDQTSDEVTVETTSVFRADFLSELDAPAQAGTESAVSGVEGLPPGSALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLENNEFNVVDVGSLNGTYVNREPVDSAVLANGDEVQIGKFRLVFLTGPKQGEDDGSTGGP
>NC_018078.1|WP_003409239.1|2348926_2349670_-|MerR-family-transcriptional-regulator
MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTASVSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSAVRDVLHR
>NC_018078.1|WP_003409207.1|2361692_2363156_-|FAD-binding-protein
MSTDIPATVSAETVTSWSDDVDVTVIGFGIAGGCAAVSAAAAGARVLVLERAAAAGGTTALAGGHFYLGGGTTVQLATGHPDSPEEMYKYLVAVSREPDHDKIRAYCDGSVEHFNWLEGLGFQFERSYFPGKAVIQPNTEGLMFTGNEKVWPFLELAVPAPRGHKVPVPGDTGGAAMVIDLLLKRAASLGIQIRYETGATELIVDGTGKVTGVMWKRFSETGAIKAKSVIIAAGGFVMNPDMVAKYTPKLAEKPFVLGNTYDDGLGIRLGVSAGGATQHMDQMFITAPPYPPSILLTGIIVNKLGQRFVAEDSYHSRTAGFIMEQPDSAAYLIVDEAHLEHPKMPLVPLIDGWETVVEMEAALGIPPGNLAATLDRYNAYAARGADPDFHKQPEFLAAQDNGPWGAFDMSLGKAMYAGFTLGGLATSVDGQVLRDDGAVVAGLYAVGACASNIAQDGKGYASGTQLGEGSFFGRRAGAHAAARAQGM
>NC_018078.1|WP_003409205.1|2363790_2364495_-|TetR/AcrR-family-transcriptional-regulator
MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH
>NC_018078.1|WP_003409204.1|2364557_2365223_-|hypothetical-protein
MVRLVPRAFAATVALLAAGFSPATASADPVLVFPGMEIRQDNHVCTLGYVDPALKIAFTAGHCRGGGAVTSRDYKVIGHLRAFRDNTPSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAVCHFGVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQIVGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA
>NC_018078.1|WP_003901259.1|2365327_2366230_-|sterol-desaturase-family-protein
MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEPRTIDKSNAAASLVTSR
>NC_018078.1|WP_003409199.1|2366638_2367070_+|DUF4189-domain-containing-protein
MITNLRRRTAMAAAGLGAALGLGILLVPTVDAHLANGSMSEVMMSEIAGLPIPPIIHYGAIAYAPSGASGKAWHQRTPARAEQVALEKCGDKTCKVVSRFTRCGAVAYNGSKYQGGTGLTRRAAEDDAVNRLEGGRIVNWACN
>NC_018078.1|WP_003409193.1|2367391_2368594_+|NAD(P)/FAD-dependent-oxidoreductase
MTRVVVIGSGFAGLWAALGAARRLDELAVPAGTVDVMVVSNKPFHDIRVRNYEADLSACRIPLGDVLGPAGVAHVTAEVTAIDADGRRVTTSTGASYSYDRLVLASGSHVVKPALPGLAEFGFDVDTYDGAVRLQQHLQGLAGGPLTSAAATVVVVGAGLTGIETACELPGRLHALFARGDGVTPRVVLIDHNPFVGSDMGLSARPVIEQALLDNGVETRTGVSVAAVSPGGVTLSSGERLAAATVVWCAGMRASRLTEQLPVARDRLGRLQVDDYLRVIGVPAMFAAGDVAAARMDDEHLSVMSCQHGRPMGRYAGCNVINDLFDQPLLALRIPWYVTVLDLGSAGAVYTEGWERKVVSQGAPAKTTKQSINTRRIYPPLNGSRADLLAAAAPRVQPRP
>NC_018078.1|WP_003899032.1|2368603_2369308_-|MgtC/SapB-family-protein
MQTLTVADFALRLAVGVGCGAIIGLERQWRARMAGLRTNALVATGATLFVLYAVATEDSSPTRVASYVVSGIGFLGGGVILREGFNVRGLNTAATLWCSAAVGVLAASGHLVFTLIGTGTIVAVHLLGRPLGRLVDRDNAVEDEGLQPYQVRVICRPKAETYVRAHIVQRTSSNDITLRGIRTGPAGDDNITLTAHLLMVGHTPAKLERLVAELSLQPGVYAVHWYAGEHAQAE
>NC_018078.1|WP_003409188.1|2369461_2369818_-|DUF732-domain-containing-protein
MQLQRTMGQCRPMRMLVALLLSAATMIGLAAPGKADPTGDDAAFLAALDQAGITYADPGHAITAAKAMCGLCANGVTGLQLVADLRDYNPGLTMDSAAKFAAIASGAYCPEHLEHHPS
>NC_018078.1|WP_003899030.1|2370062_2371469_-|PPE-family-protein
MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAIFGPTGATTYQNLFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH
>NC_018078.1|WP_003906680.1|2371600_2372830_-|PPE-family-protein
MDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD

Crispr_ID: NC_018078_11

• CRISPR_ID: NC_018078_11
• CRISPR_location: 3737581-3738428
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 11 spacers

Consensus repeat of NC_018078_11

Consensus_repeat	Method
CCGCCGNNNCCNCCGTNNCCGCC	CRT

spacers of NC_018078_11

>11.1|3737604|52|NC_018078|CRT
GTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATG
>11.2|3737679|58|NC_018078|CRT
CTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCG
>11.3|3737760|43|NC_018078|CRT
GTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATG
>11.4|3737826|79|NC_018078|CRT
GTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGG
>11.5|3737928|34|NC_018078|CRT
GTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCA
>11.6|3737985|61|NC_018078|CRT
GCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACA
>11.7|3738069|31|NC_018078|CRT
AACGCCCACTTCACCGCCGTTGCCGCCGTCA
>11.8|3738123|55|NC_018078|CRT
CAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCA
>11.9|3738201|37|NC_018078|CRT
CTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGTG
>11.10|3738261|70|NC_018078|CRT
CTTGCCGCCGTTGCCGCCCATACCGCCATCGGCACCGGGCGAACCCAAGGTGGCGGCGTCGAATCCGTTT
>11.11|3738354|52|NC_018078|CRT
GGCACCGCCCTTGCCGCCGACGCCGCCGTCGCCGTGCTGGGCGCCGCCATTT

CRISPR arrays and Neighbor proteins around NC_018078_11

CRISPR arrays

The CRISPR arrays of NC_018078_11

>merge|NC_018078|11|3737581-3738428|CRT
CCGCCGTTGCCGCCGGCACCGCCGTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCCTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCGCCCCCGTTGCCGCCCTTGCCGCCGTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATGCCGCCGTTGCCGCCGTTGCCGCCGTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGGCCGCCGTTACCACCGGCGCCGCCGTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCACCTCCGTTGCCACCGTTGCCGCCGCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACACCGCCGGCCCCACCCTTGCCGCCAACGCCCACTTCACCGCCGTTGCCGCCGTCACCGCCGGCACCCTGGTTGACGGCCAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCACCGCCGGCGCCGCCGTCCCCGGCCTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGTGCCGCCACCACCGCCGTCACCGCCCTTGCCGCCGTTGCCGCCCATACCGCCATCGGCACCGGGCGAACCCAAGGTGGCGGCGTCGAATCCGTTTCCGCCGGCGCCGCCGCTACCGCCGGCACCGCCCTTGCCGCCGACGCCGCCGTCGCCGTGCTGGGCGCCGCCATTTCCGCCATTACCGCCGTGGCCCCC

>NC_018078|11|5|3737581-3738428|CRT
CCGCCGTTGCCGCCGGCACCGCC	GTTGCCGGCCTTAGCGAACGTGGCGAAGGCGTCACCACCCTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	CTGTCCGCCATTCGCGCCATTGGCGGACGCGGAGAAGTCTTGGCCGTTGGCTCCGGCG
CCCCCGTTGCCGCCCTTGCCGCC	GTCCCCGCCCGTGCCGGCCGCCGATCCGCCGTTGCCGCCGATG
CCGCCGTTGCCGCCGTTGCCGCC	GTTGAGGGCAAGGCCGGTGCCGGCGACGCCATTTCCGCCGGCACCACCCGCACCGCCGTTACCGACCGACCCGCCATGG
CCGCCGTTACCACCGGCGCCGCC	GTTTTCTCCCGCGACGGTGGGGGTGGCGCCGGCA
CCTCCGTTGCCACCGTTGCCGCC	GCTGGTGGGCGCGGTGCCGTTCGCCCCGGCCGAACCGTTCAGGGCCGGGTTCGCGCTAACA
CCGCCGGCCCCACCCTTGCCGCC	AACGCCCACTTCACCGCCGTTGCCGCCGTCA
CCGCCGGCACCCTGGTTGACGGC	CAAGGTCACATCACCGGCGGCACCGGCTCCGCCATCACCGGCCTTGCCGCCGTCA
CCGCCGGCGCCGCCGTCCCCGGC	CTTGCCGGCGGTGCCGGCGACCGCGGTGCCGCCGGTG
CCGCCACCACCGCCGTCACCGCC	CTTGCCGCCGTTGCCGCCCATACCGCCATCGGCACCGGGCGAACCCAAGGTGGCGGCGTCGAATCCGTTT
CCGCCGGCGCCGCCGCTACCGCC	GGCACCGCCCTTGCCGCCGACGCCGCCGTCGCCGTGCTGGGCGCCGCCATTT
CCGCCATTACCGCCGTGGCCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003900028.1|3723148_3724498_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	unknown	unknown	gnl|CDD|236105
NC_018078.1|WP_009940431.1|3720937_3721570_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NC_018078.1|WP_003417619.1|3740171_3740429_-|DUF3017-domain-containing-protein	unknown	unknown	gnl|CDD|378602
NC_018078.1|WP_003900026.1|3718278_3718719_+|heavy-metal-responsive-transcriptional-regulator	unknown	unknown	gnl|CDD|133398
NC_018078.1|WP_025983990.1|3726385_3733999_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_018078.1|WP_003417738.1|3764319_3765114_-|hypothetical-protein	unknown	unknown	gnl|CDD|369658
NC_018078.1|WP_003417458.1|3724509_3725649_+|homoserine-O-acetyltransferase	unknown	unknown	gnl|CDD|234678
NC_018078.1|WP_003417421.1|3716958_3717804_-|DUF732-domain-containing-protein	unknown	unknown	gnl|CDD|368380
NC_018078.1|WP_009938650.1|3752301_3752589_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003417452.1|3721636_3722866_-|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl|CDD|236226
NC_018078.1|WP_003417461.1|3725645_3726377_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|369777
NC_018078.1|WP_009938649.1|3740684_3750158_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_018078.1|WP_003417435.1|3718752_3719622_-|inner-membrane-protein-YhjD	unknown	unknown	gnl|CDD|188082
NC_018078.1|WP_157132559.1|3765464_3765683_-|hypothetical-protein	unknown	unknown	gnl|CDD|366708
NC_018078.1|WP_049961743.1|3750783_3751230_+|transposase	unknown	unknown	gnl|CDD|376564
NC_018078.1|WP_003417739.1|3765195_3765567_-|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223354
NC_018078.1|WP_009939158.1|3752925_3764076_-|PPE-family-protein	unknown	unknown	gnl|CDD|366325
NC_018078.1|WP_003417440.1|3719642_3720653_-|tryptophan--tRNA-ligase	unknown	unknown	gnl|CDD|234866
NC_018078.1|WP_003906084.1|3765709_3765973_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003900675.1|3751266_3752007_-|transposase	unknown	unknown	gnl|CDD|376574

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003900028.1|3723148_3724498_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase	gnl|CDD|236105	PRK07812, PRK07812, O-acetylhomoserine aminocarboxypropyltransferase; Validated.	0
NC_018078.1|WP_009940431.1|3720937_3721570_+|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	1.23792e-15
NC_018078.1|WP_003417619.1|3740171_3740429_-|DUF3017-domain-containing-protein	gnl|CDD|378602	pfam11222, DUF3017, Protein of unknown function (DUF3017). This bacterial family of proteins with unknown function appear to be restricted to Actinobacteria.	3.92596e-11
NC_018078.1|WP_003900026.1|3718278_3718719_+|heavy-metal-responsive-transcriptional-regulator	gnl|CDD|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	2.31191e-56
NC_018078.1|WP_025983990.1|3726385_3733999_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.06966e-84
NC_018078.1|WP_003417738.1|3764319_3765114_-|hypothetical-protein	gnl|CDD|369658	pfam08031, BBE, Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine.	2.38492e-05
NC_018078.1|WP_003417458.1|3724509_3725649_+|homoserine-O-acetyltransferase	gnl|CDD|234678	PRK00175, metX, homoserine O-acetyltransferase; Provisional.	0
NC_018078.1|WP_003417421.1|3716958_3717804_-|DUF732-domain-containing-protein	gnl|CDD|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	8.32313e-18
NC_018078.1|WP_003417452.1|3721636_3722866_-|NADP-dependent-isocitrate-dehydrogenase	gnl|CDD|236226	PRK08299, PRK08299, NADP-dependent isocitrate dehydrogenase.	0
NC_018078.1|WP_003417461.1|3725645_3726377_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	1.03104e-26
NC_018078.1|WP_009938649.1|3740684_3750158_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	9.98029e-79
NC_018078.1|WP_003417435.1|3718752_3719622_-|inner-membrane-protein-YhjD	gnl|CDD|188082	TIGR00766, Uncharacterized_protein_Dda3937_02003, inner membrane protein YhjD. This family, including YhjD in E. coli, is a conserved inner membrane protein homologous YihY, which in turn was incorrectly assigned to be ribonuclease BN. This, any suggestion this family is similar to ribonucleases should be removed. [Transcription, Degradation of RNA].	3.67774e-123
NC_018078.1|WP_157132559.1|3765464_3765683_-|hypothetical-protein	gnl|CDD|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	3.12703e-05
NC_018078.1|WP_049961743.1|3750783_3751230_+|transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.45693e-11
NC_018078.1|WP_003417739.1|3765195_3765567_-|FAD-binding-oxidoreductase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	7.3689e-14
NC_018078.1|WP_009939158.1|3752925_3764076_-|PPE-family-protein	gnl|CDD|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	8.31505e-80
NC_018078.1|WP_003417440.1|3719642_3720653_-|tryptophan--tRNA-ligase	gnl|CDD|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	0
NC_018078.1|WP_003900675.1|3751266_3752007_-|transposase	gnl|CDD|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.82865e-20

Protein sequences

>NC_018078.1|WP_025983990.1|3726385_3733999_-|PPE-family-protein
MSFVVMPPEINSLLIYTGAGPGPLLAAAAAWDELAAELGSAAAAFGSVTSGLVGGIWQGPSSVAMAAAAAPYAGWLSAAAASAESAAGQARAVVGVFEAALAATVDPFVIAANRSRLVSLALSNLFGQNTPAIAAAEFDYELMWAQDVAAMLGYHTGASAAAEALAPFGSPLASLAAAAEPAKSLAVNLGLANVGLFNAGSGNVGSYNVGAGNVGSYNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGEANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGVLWRGDYQGLLGFSSGANVLPVIPLSLDINGGVGAITIEPIHILPDIPININETLYLGPLVVPPINVPAISLGVGIPNISIGPIKINPITLWPAQNFNQTITLAWPVSSITIPQIQQVALSPSPIPTTLIGPIHINTGFSIPVTFSYSTPALTLFPVGLSIPTGGPLTLTLGVTAGTEAFTIPGFSIPEQPLPLAINVIGHINALSTPAITIDNIPLNLHAIGGVGPVDIVGGNVPASPGFGNSTTAPSSGFFNTGAGGVSGFGNVGAHTSGWFNQSTQAMQVLPGTVSGYFNSGTLMSGIGNVGTQLSGMLSGGALGGNNFGLGNIGFDNVGFGNAGSSNFGLANMGIGNIGLANTGNGNIGIGLSGDNLTGFGGFNSGSENVGLFNSGTGNVGFFNSGTGNLGVFNSGSHNTGFFLTGNNINVLAPFTPGTLFTISEIPIDLQVIGGIGPIHVQPIDIPAFDIQITGGFIGIREFTLPEITIPAIPIHVTGTVGLEGFHVNPAFVLFGQTAMAEITADPVVLPDPFITIDHYGPPLGPPGAKFPSGSFYLSISDLQINGPIIGSYGGPGTIPGPFGATFNLSTSSLALFPAGLTVPDQTPVTVNLTGGLDSITLFPGGLAFPENPVVSLTNFSVGTGGFTVFPQGFTVDRIPVDLHTTLSIGPFPFRWDYIPPTPANGPIPAVPGGFGLTSGLFPFHFTLNGGIGPISIPTTTVVDALNPLLTVTGNLEVGPFTVPDIPIPAINFGLDGNVNVSFNAPATTLLSGLGITGSIDISGIQITNIQTQPAQLFMSVGQTLFLFDFRDGIELNPIVIPGSSIPITMAGLSIPLPTVSESIPLNFSFGSPASTVKSMILHEILPIDVSINLEDAVFIPATVLPAIPLNVDVTIPVGPINIPIITEPGSGNSTTTTSDPFSGLAVPGLGVGLLGLFDGSIANNLISGFNSAVGIVGPNVGLSNLGGGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNIGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDINTGVANSGDVNTGAFISGNYSNGAFWTGDYQGLLDFSFPVGPLIPQTHLVHLRETVNLGPIHIDPIHVHIPPLLDIDQTIDLGSFTVAPITVAPIALDYHETFDLGPLVIFPPMNIPATVIESFSTAPGGPAPPPFVIPATSNVFISTVDFATGNNVIGPFSGALAPTTIQLGASGPSFSVLNLSIPPIHIPGLTIPSVPLRIDVDGGIPGFTLFPDGLTFPKIPVHVDAFAGIPDFTIFPNGYTIDPIPLQLNLDLTLGPVHILIDLPAVPGFGNTTGAPSSGFFNSGAGGVSGFGNVGAMVSGGWNQAPSALLGGGSGVFNAGTLHSGVLNFGSGMSGLFNTSVLGLGAPALVSGLGSVGQQLSGLLASGTALHQGLVLNFGLADVGLGNVGLGNVGDFNLGAGNVGGFNVGGGNIGGNNVGLGNVGWGNFGLGNSGLTPGLMGLGNIGFGNAGSYNFGLANMGVGNIGFANTGSGNFGIGLTGDNLTGFGGFNTGSGNVGLFNSGTGNVGFFNSGTGNWGVFNSGSYNTGIGNSGIASTGLFNAGGFNTGVVNAGSYNTGSFNAGQANTGGFNPGSVNTGWLNTGDTNTGVANSGDVNTGAFISGNYSNGAFWRGDYQGLLGFSYTSTIIPEFTVANIHASGGAGPIIVPSIQFPAIPLDLSATGHIGGFTIPPVSISPITVRIDPVFDLGPITVQDITIPALGLDPATGVTVGPIFSSGSIIDPFSLTLLGFINVNVPAIQTAPSEILPFTVLLSSLGVTHLTPEITIPGFHIPVDPIHVELPLSVTIGPFVSPEITIPQLPLGLALSGATPAFAFPLEITIDRIPVVLDVNALLGPINAGLVIPPVPGFGNTTAVPSSGFFNIGGGGGLSGFHNLGAGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGADISGVYNTGALGLITSALVSGFGNVGQQLAGLIYTGTGP
>NC_018078.1|WP_003417461.1|3725645_3726377_+|class-I-SAM-dependent-methyltransferase
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA
>NC_018078.1|WP_003417458.1|3724509_3725649_+|homoserine-O-acetyltransferase
MTISDVPTQTLPAEGEIGLIDVGSLQLESGAVIDDVCIAVQRWGKLSPARDNVVVVLHALTGDSHITGPAGPGHPTPGWWDGVAGPGAPIDTTRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVQADVAALAALGITEVAAVVGGSMGGARALEWVVGYPDRVRAGLLLAVGARATADQIGTQTTQIAAIKADPDWQSGDYHETGRAPDAGLRLARRFAHLTYRGEIELDTRFANHNQGNEDPTAGGRYAVQSYLEHQGDKLLSRFDAGSYVILTEALNSHDVGRGRGGVSAALRACPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLRVVESVYGHDGFLVETEAVGELIRQTLGLADREGACRR
>NC_018078.1|WP_003900028.1|3723148_3724498_+|bifunctional-o-acetylhomoserine/o-acetylserine-sulfhydrylase
MSADSNSTDADPTAHWSFETKQIHAGQHPDPTTNARALPIYATTSYTFDDTAHAAALFGLEIPGNIYTRIGNPTTDVVEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLGIEVSFVDDPDDLDTWQAAVRPNTKAFFAETISNPQIDLLDTPAVSEVAHRNGVPLIVDNTIATPYLIQPLAQGADIVVHSATKYLGGHGAAIAGVIVDGGNFDWTQGRFPGFTTPDPSYHGVVFAELGPPAFALKARVQLLRDYGSAASPFNAFLVAQGLETLSLRIERHVANAQRVAEFLAARDDVLSVNYAGLPSSPWHERAKRLAPKGTGAVLSFELAGGIEAGKAFVNALKLHSHVANIGDVRSLVIHPASTTHAQLSPAEQLATGVSPGLVRLAVGIEGIDDILADLELGFAAARRFSADPQSVAAF
>NC_018078.1|WP_003417452.1|3721636_3722866_-|NADP-dependent-isocitrate-dehydrogenase
MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN
>NC_018078.1|WP_009940431.1|3720937_3721570_+|alpha/beta-fold-hydrolase
MLADHVERQLDELGWETSHIVGNSLGGWVAFELERRGRARSVTGIAPAGGWTRWSPVKFEVIAKFIAGAPILAVAHILGQRALRLPFSRLLATLPISATPDGVSERELSGIIDDAAHCPAYFQLLVKALVLPGLQELEHTAVPSHVVLCEQDRVVPPSRFSRHFTDSLPAGHRLTVLDGVGHVPMFEAPGRITELITSFIEECCPHVRAS
>NC_018078.1|WP_003417440.1|3719642_3720653_-|tryptophan--tRNA-ligase
MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADVLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL
>NC_018078.1|WP_003417435.1|3718752_3719622_-|inner-membrane-protein-YhjD
MGELAEPGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLTYYTIFAIFPLLMVGFGVGGFALSRRPELLTTLEERIRTSVSGAVGQQLVDLMNSAIDARASVGVIGLATAAWVGLGWMWHLREALSQMWAHPVAPAGYLRTKLSDLAAMVGTFVVIVATIALTVLGHARPMAAVLRWLEIPQFSVFDEIFRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGFELFKQVGAIYLQIVLRSPAGAVFGPVLGLMVFAFVTAWLILFATAWAATASA
>NC_018078.1|WP_003900026.1|3718278_3718719_+|heavy-metal-responsive-transcriptional-regulator
MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA
>NC_018078.1|WP_003417421.1|3716958_3717804_-|DUF732-domain-containing-protein
MFTGIASHAGALGAALVVLIGAAILHDGPAAADPNQDDRFLALLEKKEIPAVANVPRVIDAAHKVCRKLDGGMPVNDIVDGLRNDAYNIDPVMRLYPVRLTTTMTRFISAAVEIYCPNHHSKMAFAMANFEPGSNEPTHRVAASTRSAVNSGSDLRASVSDMTIMSPGWREPTGAMLASVLGAVRAGDPLIPNPPPIPVPPPAAQTLIPPPPIVAPPPPRPAPPQQPPPPPPEVEPPAGVPQSGGAAGSGGAGSGGGGGGDGPVEPSPARPMPPGFIRLAP
>NC_018078.1|WP_003417619.1|3740171_3740429_-|DUF3017-domain-containing-protein
MTVRAVLRRTVGAQWPILAGVNFWRRGALLIGIGVGVAAVLRLVLSEERAGLLVVRSKGIDFVTTVTVAAAMVYIASTIDPLGTG
>NC_018078.1|WP_009938649.1|3740684_3750158_-|PPE-family-protein
MNFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAQAVAVAGQARAAVAAFEAALAATVDPAAVAVNRMAMRALAMSNLLGQNAAAIAAVEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLNALFAGPAKMLRLNAGLGNVGNYNVGLGNVGIFNLGAANVGAQNLGAANAGSGNFGFGNIGNANFGFGNSGLGLPPGMGNIGLGNAGSSNYGLANLGVGNIGFANTGSNNIGIGLTGDNLTGIGGLNSGTGNLGLFNSGTGNIGFFNSGTGNFGVFNSGSYNTGVGNAGTASTGLFNVGGFNTGVANVGSYNTGSFNAGNTNTGGFNPGNVNTGWLNTGNTNTGIANSGNVNTGAFISGNFSNGVLWRGDYEGLWGLSGGSTIPAIPIGLELNGGVGPITVLPIQILPTIPLNIHQTFSLGPLVVPDIVIPAFGGGTAIPISVGPITISPITLFPAQNFNTTFPVGPFFGLGVVNISGIEIKDLAGNVTLQLGNLNIDTRINQSFPVTVNWSTPAVTIFPNGISIPNNPLALLASASIGTLGFTIPGFTIPAAPLPLTIDIDGQIDGFSTPPITIDRIPLNLGASVTVGPILINGVNIPATPGFGNTTTAPSSGFFNSGDGGVSGFGNFGAGSSGWWNQAQTEVAGAGSGFANFGSLGSGVLNFGSGVSGLYNTGGLPPGTPAVVSGIGNVGEQLSGLSSAGTALNQSLIINLGLADVGSVNVGFGNVGDFNLGAANIGDLNVGLGNVGGGNVGFGNIGDANFGLGNAGLAAGLAGVGNIGLGNAGSGNVGFGNMGVGNIGFGNTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNVGLFNSGTGNFGLFNSGSFNTGIGNGGTGSTGLFNAGNFNTGVANPGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGVANSGNVDTGALMSGNFSNGILWRGNFEGLFGLNVGITIPEFPIHWTSTGGIGPIIIPDTTILPPIHLGLTGQANYGFAVPDIPIPAIHIDFDGAADAGFTAPATTLLSALGITGQFRFGPITVSNVQLNPFNVNLKLQFLHDAFPNEFPDPTISVQIQVAIPLTSATLGGLALPLQQTIDAIELPAISFSQSIPIDIPPIDIPASTINGISMSEVVPIDVSVDIPAVTITGTRIDPIPLNFDVLSSAGPINISIIDIPALPGFGNSTELPSSGFFNTGGGGGSGIANFGAGVSGLLNQASSPMVGTLSGLGNAGSLASGVLNSGVDISGMFNVSTLGSAPAVISGFGNLGNHVSGVSIDGLLAMLTSGGSGGSGQPSIIDAAIAELRHLNPLNIVNLGNVGSYNLGFANVGDVNLGAGNLGNLNLGGGNLGGQNLGLGNLGDGNVGFGNLGHGNVGFGNSGLGALPGIGNIGLGNAGSNNVGFGNMGLGNIGFGNTGTNNLGIGLTGDNQTGFGGLNSGAGNLGLFNSGTGNIGFFNTGTGNWGLFNSGSYNTGIGNSGTGSTGLFNAGSFNTGLANAGSYNTGSLNAGNTNTGGFNPGNVNTGWFNAGHTNTGGFNTGNVNTGAFNSGSFNNGALWTGDHHGLVGFSYSIEITGSTLVDINETLNLGPVHIDQIDIPGMSLFDIHELVNIGPFRIEPIDVPAVVLDIHETMVIPPIVFLPSMTIGGQTYTIPLDTPPAPAPPPFRLPLLFVNALGDNWIVGASNSTGMSGGFVTAPTQGILIHTGPSSATTGSLALTLPTVTIPTITTSPIPLKIDVSGGLPAFTLFPGGLNIPQNAIPLTIDASGVLDPITIFPGGFTIDPLPLSLALNISVPDSSVPIIIVPPTPGFGNATATPSSGFFNSGAGGVSGFGNFGAGSSGWWNQAHAALAGAGSGVLNVGTLNSGVLNVGSGISGLYNTAIVGLGTPALVSGAGNVGQQLSGVLAAGTALTQSPIINLGLADVGNYNLGLGNVGDFNLGAANLGDLNLGLGNIGNANVGFGNIGHGNVGFGNSGLGAALGIGNIGLGNAGSTNVGLANMGVGNIGFANTGTNNLGIGLTGDNQTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNWGLFNSGSFNTGIGNSGTGSTGLFNAGGFTTGLANAGSYNTGSFNVGDTNTGGFNPGSINTGWFNTGNANTGIANSGNVDTGALMSGNFSNGILWRGNYEGLFSYSYSLDVPRITILDAHFTGAFGPVVVPPIPVPAINAHLTGNAAMGAFTIPQIDIPALNPNVTGSVGFGPIAVPSVTIPALTAARAVLDMAASVGATSEIEPFIVWTSSGAIGPTWYSVGRIYNAGDLFVGGNIISGIPTLSTTGPVHAVFNAASQAFNTPALNIHQIPLGFQVPGSIDAITLFPGGLTFPANSLLNLDVFVGTPGATIPAITFPEIPANADGELYVIAGDIPLINIPPTPGIGNTTTVPSSGFFNTGAGGGSGFGNFGANMSGWWNQAHTALAGAGSGIANVGTLHSGVLNLGSGLSGIYNTSTLPLGTPALVSGLGNVGDHLSGLLASNVGQNPITIVNIGLANVGNGNVGLGNIGNLNLGAANIGDVNLGFGNIGDVNLGFGNIGGGNVGFGNIGDANFGFGNSGLAAGLAGMGNIGLGNAGSGNVGWANMGLGNIGFGNTGTNNLGIGLTGDNQSGIGGLNSGTGNIGLFNSGTGNIGFFNSGTANFGLFNSGSYNTGIGNSGVASTGLVNAGGFNTGVANAGSYNTGSFNAGDTNTGGFNPGSTNTGWFNTGNANTGVANAGNVNTGALITGNFSNGILWRGNYEGLAGFSFGYPIPLFPAVGADVTGDIGPATIIPPIHIPSIPLGFAAIGHIGPISIPNIAIPSIHLGIDPTFDVGPITVDPITLTIPGLSLDAAVSEIRMTSGSSSGFKVRPSFSFFAVGPDGMPGGEVSILQPFTVAPINLNPTTLHFPGFTIPTGPIHIGLPLSLTIPGFTIPGGTLIPQLPLGLGLSGGTPPFDLPTVVIDRIPVELHASTTIGPVSLPIFGFGGAPGFGNDTTAPSSGFFNTGGGGGSGFSNSGSGMSGVLNAISDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGTLGLVTSAFVSGFMNVGQQLSGLLFAGTGP
>NC_018078.1|WP_049961743.1|3750783_3751230_+|transposase
MDAAITACHHIAIRDDVGARSIRFSVEPTLAGLRTLTDKLSGYDDIDATVEPTSMTWLPLTIAVENAGDTMHMAGARHCARLRGAIVGKSKSDVIDAEVLTRASEVFDLTPLTLPTPAQLALRRSVIRRAGAVIDANRSWRRLMSLAR
>NC_018078.1|WP_003900675.1|3751266_3752007_-|transposase
MAIDPAAAYASAIRTPGLLPNAKLVVDHFHVTTLANDALTAVRRRVTWAFHDRRGRKIDPQWANRRRLLTARERLSDKSFAKMRNRINAVDPRAQILSAWIAKEELRTLLSTVRTGGDPHLARHHLHRFLPGASTRRSPNCSPWPPPLTSHPRSTPSWSPASPTRASVVGEVAEMLGDIDGQCVQVEVPVPERGPAGCGGLDGLGRAGVSATPRVCAAMTAVNVAGRCAGQQADVGPTPQHRCRGR
>NC_018078.1|WP_009938650.1|3752301_3752589_-|hypothetical-protein
MSRRRRRARRAGVVSISVKEYAVTSPKDLPYGEDRIMVRWNKIRWRCREDYCKLGPFTEAITQVPARVRSTLRLRRQMAKAIGDAARSVGRGRPG
>NC_018078.1|WP_009939158.1|3752925_3764076_-|PPE-family-protein
MEFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVALAVSNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLTALFASPAKALSLNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNVGFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVGLTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSGNYNTGVGNAGTASTGLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNTGAFISGNFNNGVLWVGDYQGLFGVSAGSSIPAIPIGLVLNGDIGPITIQPIPILPTIPLSIHQTVNLGPLVVPDIVIPAFGGGIGIPINIGPLTITPITLFAQQTFVNQLPFPTFSLGKITIPQIQTFDSNGQLVSFIGPIVIDTTIPGPTNPQIDLTIRWDTPPITLFPNGISAPDNPLGLLVSVSISNPGFTIPGFSVPAQPLPLSIDIEGQIDGFSTPPITIDRIPLTVGGGVTIGPITIQGLHIPAAPGVGNTTTAPSSGFFNSGAGGVSGFGNVGAGSSGWWNQAPSALLGAGSGVGNVGTLGSGVLNLGSGISGFYNTSVLPFGTPAAVSGIGNLGQQLSGVSAAGTTLRSMLAGNLGLANVGNFNTGFGNVGDVNLGAANIGGHNLGLGNVGDGNLGLGNIGHGNLGFANLGLTAGAAGVGNVGFGNAGINNYGLANMGVGNIGFANTGTGNIGIGLVGDHRTGIGGLNSGIGNIGLFNSGTGNVGFFNSGTGNFGIGNSGRFNTGIGNSGTASTGLFNAGSFSTGIANTGDYNTGSFNAGDTNTGGFNPGGINTGWFNTGHANTGLANAGTFGTGAFMTGDYSNGLLWRGGYEGLVGVRVGPTISQFPVTVHAIGGVGPLHVAPVPVPAVHVEITDATVGLGPFTVPPISIPSLPIASITGSVDLAANTISPIRALDPLAGSIGLFLEPFRLSDPFITIDAFQVVAGVLFLENIIVPGLTVSGQILVTPTPIPLTLNLDTTPWTLFPNGFTIPAQTPVTVGMEVANDGFTFFPGGLTFPRASAGVTGLSVGLDAFTLLPDGFTLDTVPATFDGTILIGDIPIPIIDVPAVPGFGNTTTAPSSGFFNTGGGGGSGFANVGAGTSGWWNQGHDVLAGAGSGVANAGTLSSGVLNVGSGISGWYNTSTLGAGTPAVVSGIGNLGQQLSGFLANGTVLNRSPIVNIGWADVGAFNTGLGNVGDLNWGAANIGAQNLGLGNLGSGNVGFGNIGAGNVGFANSGPAVGLAGLGNVGLSNAGSNNWGLANLGVGNIGLANTGTGNIGIGLVGDYQTGIGGLNSGSGNIGLFNSGTGNVGFFNTGTGNFGLFNSGSFNTGIGNSGTGSTGLFNAGNFNTGIANPGSYNTGSFNVGDTNTGGFNPGDINTGWFNTGIMNTGTRNTGALMSGTDSNGMLWRGDHEGLFGLSYGITIPQFPIRITTTGGIGPIVIPDTTILPPLHLQITGDADYSFTVPDIPIPAIHIGINGVVTVGFTAPEATLLSALKNNGSFISFGPITLSNIDIPPMDFTLGLPVLGPITGQLGPIHLEPIVVAGIGVPLEIEPIPLDAISLSESIPIRIPVDIPASVIDGISMSEVVPIDASVDIPAVTITGTTISAIPLGFDIRTSAGPLNIPIIDIPAAPGFGNSTQMPSSGFFNTGAGGGSGIGNLGAGVSGLLNQAGAGSLVGTLSGLGNAGTLASGVLNSGTAISGLFNVSTLDATTPAVISGFSNLGDHMSGVSIDGLIAILTFPPAESVFDQIIDAAIAELQHLDIGNALALGNVGGVNLGLANVGEFNLGAGNVGNINVGAGNLGGSNLGLGNVGTGNLGFGNIGAGNFGFGNAGLTAGAGGLGNVGLGNAGSGSWGLANVGVGNIGLANTGTGNIGIGLTGDYRTGIGGLNSGTGNLGLFNSGTGNIGFFNTGTGNFGLFNSGSYSTGVGNAGTASTGLFNAGNFNTGLANAGSYNTGSLNVGSFNTGGVNPGTVNTGWFNTGHTNTGLFNTGNVNTGAFNSGSFNNGALWTGDYHGLVGFSFSIDIAGSTLLDLNETLNLGPIHIEQIDIPGMSLFDVHEIVEIGPFTIPQVDVPAIPLEIHESIHMDPIVLVPATTIPAQTRTIPLDIPASPGSTMTLPLISMRFEGEDWILGSTAAIPNFGDPFPAPTQGITIHTGPGPGTTGELKISIPGFEIPQIATTRFLLDVNISGGLPAFTLFAGGLTIPTNAIPLTIDASGALDPITIFPGGYTIDPLPLHLALNLTVPDSSIPIIDVPPTPGFGNTTATPSSGFFNSGAGGVSGFGNVGSNLSGWWNQAASALAGSGSGVLNVGTLGSGVLNVGSGVSGIYNTSVLPLGTPAVLSGLGNVGHQLSGVSAAGTALNQIPILNIGLADVGNFNVGFGNVGDVNLGAANLGAQNLGLGNVGTGNLGFANVGHGNIGFGNSGLTAGAAGLGNTGFGNAGSANYGFANQGVRNIGLANTGTGNIGIGLVGDNLTGIGGLNSGAGNIGLFNSGTGNIGFFNSGTGNFGIGNSGSFNTGIGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNAGDTNTGGFNPGTINTGWFNTGHTNTGIANSGNVGTGAFMSGNFSNGLLWRGDHEGLFSLFYSLDVPRITIVDAHLDGGFGPVVLPPIPVPAVNAHLTGNVAMGAFTIPQIDIPALTPNITGSAAFRIVVGSVRIPPVSVIVEQIINASVGAEMRIDPFEMWTQGTNGLGITFYSFGSADGSPYATGPLVFGAGTSDGSHLTISASSGAFTTPQLETGPITLGFQVPGSVNAITLFPGGLTFPATSLLNLDVTAGAGGVDIPAITWPEIAASADGSVYVLASSIPLINIPPTPGIGNSTITPSSGFFNAGAGGGSGFGNFGAGTSGWWNQAHTALAGAGSGFANVGTLHSGVLNLGSGVSGIYNTSTLGVGTPALVSGLGNVGHQLSGLLSGGSAVNPVTVLNIGLANVGSHNAGFGNVGEVNLGAANLGAHNLGFGNIGAGNLGFGNIGHGNVGVGNSGLTAGVPGLGNVGLGNAGGNNWGLANVGVGNIGLANTGTGNIGIGLTGDYQTGIGGLNSGAGNLGLFNSGAGNVGFFNTGTGNFGLFNSGSFNTGVGNSGTGSTGLFNAGSFNTGVANAGSYNTGSFNVGDTNTGGFNPGSINTGWLNAGNANTGVANAGNVNTGAFVTGNFSNGILWRGDYQGLAGFAVGYTLPLFPAVGADVSGGIGPITVLPPIHIPPIPVGFAAVGGIGPIAIPDISVPSIHLGLDPAVHVGSITVNPITVRTPPVLVSYSQGAVTSTSGPTSEIWVKPSFFPGIRIAPSSGGGATSTQGAYFVGPISIPSGTVTFPGFTIPLDPIDIGLPVSLTIPGFTIPGGTLIPTLPLGLALSNGIPPVDIPAIVLDRILLDLHADTTIGPINVPIAGFGGAPGFGNSTTLPSSGFFNTGAGGGSGFSNTGAGMSGLLNAMSDPLLGSASGFANFGTQLSGILNRGAGISGVYNTGALGVVTAAVVSGFGNVGQQLSGLLFTGVGP
>NC_018078.1|WP_003417738.1|3764319_3765114_-|hypothetical-protein
MLASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPPEGFVAGSDVIGTTNPAAAQAIVAAIGTWPPAAGRASALIDSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHHAVQHFSVGGYVNYLEANAAASQYFGANLSRLTTVRRKYDPDRIMYSGLDFSTRQVAERLLPALGFRVRFGVLVIRCALCTDTVKRLGTLPNLTWSRLKVNVAVTQEQAGVMDLPALPVRRTPRR
>NC_018078.1|WP_003417739.1|3765195_3765567_-|FAD-binding-oxidoreductase
MSAATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCDALKSATVVLPGGDAVSASADDHAELFWALRGGGGGNFGVTTSMTFARFPTADCDVVRVDFAPSAAAQVLVG
>NC_018078.1|WP_157132559.1|3765464_3765683_-|hypothetical-protein
MRGGGHSYIGASSANGAMVLDLLGLPGGVHFDSATRNVRCRPRPISMRSIKRWPVRAGRFRPAAARPWVWRV
>NC_018078.1|WP_003906084.1|3765709_3765973_-|hypothetical-protein
MMSRQTFLRGAVGAPATSAVFPTILARATPGDGWASLASSIGGQVLLPANGRAFTSGKQIFNSNYSGLNPAAVVTVASQADVRKAVS

Crispr_ID: NC_018078_12

• CRISPR_ID: NC_018078_12
• CRISPR_location: 3984764-3984923
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_018078_12

Consensus_repeat	Method
AACTCCGGCAGCGGCAATATCGGC	CRISPRCasFinder

spacers of NC_018078_12

>12.1|3984788|21|NC_018078|CRISPRCasFinder
GGCGGCAACACCGGCAGCGGC
>12.2|3984833|21|NC_018078|CRISPRCasFinder
AGCTCCAACTTCGGCGGCGGC
>12.3|3984878|21|NC_018078|CRISPRCasFinder
AGCGGCAACCGAGGCAGCGAC

CRISPR arrays and Neighbor proteins around NC_018078_12

CRISPR arrays

The CRISPR arrays of NC_018078_12

>merge|NC_018078|12|3984764-3984923|CRISPRCasFinder
AACCAGGGCAACGCCAACCTCGGCGGCGGCAACACCGGCAGCGGCAACATCGGCAACGGAAACAAAGGCAGCTCCAACTTCGGCGGCGGCAACATCGGCAATAACAACATCGGCAGCGGCAACCGAGGCAGCGACAACTTCGGCGCCGGCAACGTCGGCA

>NC_018078|12|6|3984764-3984923|CRISPRCasFinder
AACCAGGGCAACGCCAACCTCGGC	GGCGGCAACACCGGCAGCGGC
AACATCGGCAACGGAAACAAAGGC	AGCTCCAACTTCGGCGGCGGC
AACATCGGCAATAACAACATCGGC	AGCGGCAACCGAGGCAGCGAC
AACTTCGGCGCCGGCAACGTCGGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003419328.1|3982035_3983196_-|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|181123
NC_018078.1|WP_003900711.1|3973613_3974528_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|236099
NC_018078.1|WP_003419364.1|3993559_3994411_-|arylamine-N-acetyltransferase	unknown	unknown	gnl|CDD|225073
NC_018078.1|WP_003900097.1|3985875_3986664_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|236110
NC_018078.1|WP_003419325.1|3978916_3980974_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|131215
NC_018078.1|WP_003419315.1|3975384_3976128_+|enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|181174
NC_018078.1|WP_003419340.1|3986660_3987818_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_018078.1|WP_003419313.1|3974550_3975330_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|236116
NC_018078.1|WP_003419346.1|3989389_3990523_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_018078.1|WP_003906149.1|3994692_3994863_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003419352.1|3991475_3992432_+|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|224871
NC_018078.1|WP_003419324.1|3977852_3978920_+|nitronate-monooxygenase	unknown	unknown	gnl|CDD|367316
NC_018078.1|WP_003419367.1|3994395_3994662_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003900096.1|3981061_3981931_-|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|380141
NC_018078.1|WP_003900094.1|3976127_3977006_+|CoA-transferase-subunit-A	unknown	unknown	gnl|CDD|224702
NC_018078.1|WP_003900712.1|3990519_3991479_+|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|173838
NC_018078.1|WP_003419321.1|3977002_3977755_+|CoA-transferase-subunit-beta	unknown	unknown	gnl|CDD|224968
NC_018078.1|WP_003900098.1|3987865_3989389_+|3-((3aS,4S,7aS)-7a-methyl-1,-5-dioxo-octahydro-1H-inden-4-yl)propanoate--CoA-ligase	unknown	unknown	gnl|CDD|236072
NC_018078.1|WP_003419329.1|3983260_3983863_-|TetR-family-transcriptional-regulator-KstR2	unknown	unknown	gnl|CDD|366102
NC_018078.1|WP_003419356.1|3992428_3993595_+|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|235596

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003419328.1|3982035_3983196_-|acetyl-CoA-C-acetyltransferase	gnl|CDD|181123	PRK07801, PRK07801, acetyl-CoA C-acetyltransferase.	0
NC_018078.1|WP_003900711.1|3973613_3974528_-|SDR-family-oxidoreductase	gnl|CDD|236099	PRK07791, PRK07791, short chain dehydrogenase; Provisional.	7.58067e-170
NC_018078.1|WP_003419364.1|3993559_3994411_-|arylamine-N-acetyltransferase	gnl|CDD|225073	COG2162, NhoA, Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism].	1.26917e-126
NC_018078.1|WP_003900097.1|3985875_3986664_-|SDR-family-oxidoreductase	gnl|CDD|236110	PRK07831, PRK07831, SDR family oxidoreductase.	1.1239e-170
NC_018078.1|WP_003419325.1|3978916_3980974_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|131215	TIGR02160, 12-phenylacetyl-CoA_epoxidase_subunit_E, phenylacetate-CoA oxygenase/reductase, PaaK subunit. Phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA (PA-CoA) as the second catabolic step in phenylacetic acid (PA) degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA. [Energy metabolism, Other].	6.42722e-129
NC_018078.1|WP_003419315.1|3975384_3976128_+|enoyl-CoA-hydratase-family-protein	gnl|CDD|181174	PRK07938, PRK07938, enoyl-CoA hydratase family protein.	4.18883e-166
NC_018078.1|WP_003419340.1|3986660_3987818_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	6.87257e-132
NC_018078.1|WP_003419313.1|3974550_3975330_-|SDR-family-oxidoreductase	gnl|CDD|236116	PRK07856, PRK07856, SDR family oxidoreductase.	1.70513e-147
NC_018078.1|WP_003419346.1|3989389_3990523_+|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	4.1115e-133
NC_018078.1|WP_003419352.1|3991475_3992432_+|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	1.28528e-32
NC_018078.1|WP_003419324.1|3977852_3978920_+|nitronate-monooxygenase	gnl|CDD|367316	pfam03060, NMO, Nitronate monooxygenase. Nitronate monooxygenase (NMO), formerly referred to as 2-nitropropane dioxygenase (NPD) (EC:1.13.11.32), is an FMN-dependent enzyme that uses molecular oxygen to oxidize (anionic) alkyl nitronates and, in the case of the enzyme from Neurospora crassa, (neutral) nitroalkanes to the corresponding carbonyl compounds and nitrite. Previously classified as 2-nitropropane dioxygenase, but it is now recognized that this was the result of the slow ionization of nitroalkanes to their nitronate (anionic) forms. The enzymes from the fungus Neurospora crassa and the yeast Williopsis saturnus var. mrakii (formerly classified as Hansenula mrakii) contain non-covalently bound FMN as the cofactor. Active towards linear alkyl nitronates of lengths between 2 and 6 carbon atoms and, with lower activity, towards propyl-2-nitronate. The enzyme from N. crassa can also utilize neutral nitroalkanes, but with lower activity. One atom of oxygen is incorporated into the carbonyl group of the aldehyde product. The reaction appears to involve the formation of an enzyme-bound nitronate radical and an a-peroxynitroethane species, which then decomposes, either in the active site of the enzyme or after release, to acetaldehyde and nitrite.	1.54808e-102
NC_018078.1|WP_003900096.1|3981061_3981931_-|DUF559-domain-containing-protein	gnl|CDD|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	3.67664e-09
NC_018078.1|WP_003900094.1|3976127_3977006_+|CoA-transferase-subunit-A	gnl|CDD|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	6.07134e-74
NC_018078.1|WP_003900712.1|3990519_3991479_+|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	1.14474e-25
NC_018078.1|WP_003419321.1|3977002_3977755_+|CoA-transferase-subunit-beta	gnl|CDD|224968	COG2057, AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid metabolism].	4.05125e-63
NC_018078.1|WP_003900098.1|3987865_3989389_+|3-((3aS,4S,7aS)-7a-methyl-1,-5-dioxo-octahydro-1H-inden-4-yl)propanoate--CoA-ligase	gnl|CDD|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0
NC_018078.1|WP_003419329.1|3983260_3983863_-|TetR-family-transcriptional-regulator-KstR2	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	7.25468e-16
NC_018078.1|WP_003419356.1|3992428_3993595_+|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	5.98908e-167

Protein sequences

>NC_018078.1|WP_003419329.1|3983260_3983863_-|TetR-family-transcriptional-regulator-KstR2
MDRVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRWYRPGGPLTAQQVGQQYLAIVLGGITKEGV
>NC_018078.1|WP_003419328.1|3982035_3983196_-|acetyl-CoA-C-acetyltransferase
MTEAYVIDAVRTAVGKRGGALAGIHPVDLGALAWRGLLDRTDIDPAAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQAISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQWLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHFENEIITVETESGPFRVDEGPRESSLEKMAGLQPLVEGGRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIHHISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAWLKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQTMCEGGGTANVTIIERL
>NC_018078.1|WP_003900096.1|3981061_3981931_-|DUF559-domain-containing-protein
MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVELTARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPPRIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALANSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLIDAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRARDIERSTALLDLGWTIIRVTSELLWYRRGTFVGRVDAAMRAAGWRP
>NC_018078.1|WP_003419325.1|3978916_3980974_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MTDACQAEYAIAAMSTVEMDQAAPESAAHHPLPDPGESVPRLALPTIGIFLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISSIRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHGSLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAIVTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNRVGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAISTVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVDPITADATLVTFAVPEALRDAFRFEPGQHVTVRTDLGGQGIRRNYSICAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGTPLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKESTMFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTLRPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRPSYAGATVTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYACMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAVDYDA
>NC_018078.1|WP_003419324.1|3977852_3978920_+|nitronate-monooxygenase
MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLGILASATMTLDELAAAITKVKAVTDKPFGVNIRADAADAGDRVELMIREGVRVASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEGGGHTGPVATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAAGVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTELVEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWSQVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVLDAITHLQTASALVE
>NC_018078.1|WP_003419321.1|3977002_3977755_+|CoA-transferase-subunit-beta
MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDPKSLRDREIRS
>NC_018078.1|WP_003900094.1|3976127_3977006_+|CoA-transferase-subunit-A
MPDKRTALDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLDSPPFYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALRLDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFTTAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR
>NC_018078.1|WP_003419315.1|3975384_3976128_+|enoyl-CoA-hydratase-family-protein
MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAATHLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS
>NC_018078.1|WP_003419313.1|3974550_3975330_-|SDR-family-oxidoreductase
MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSANK
>NC_018078.1|WP_003900711.1|3973613_3974528_-|SDR-family-oxidoreductase
MGLVDGRVVIVTGAGGGIGRAHALAFAAEGARVVVNDIGVGLDGSPASGGSAAQDVVDEILAAGGQAVADGSDISDWDQAANLIQAAVETYGGVDVLVNNAGIVRDRMIANTSEEEFDAVIAVHLKGHFATMRHAASHWRGLSKAGKAPKDIDARIINTSSGAGLQGSVGQGNYSAAKAGIAALTLVGAAEMRRYGVTVNAIAPAARTRMTETVFAEMMAKPQEGFDAMAPENVSPLVVWLGSAESRDVTGKVFEVEGGIIRVAEGWAHGPQVDKGVKWDPAELGPVVSDLLAKSRPPVPVYGA
>NC_018078.1|WP_003900097.1|3985875_3986664_-|SDR-family-oxidoreductase
MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETAAELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLGWRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIAFLASDYSSYLTGEVISVSCQHP
>NC_018078.1|WP_003419340.1|3986660_3987818_-|acyl-CoA-dehydrogenase
MQDVEEFRAQVRGWLADNLAGEFAALKGLGGPGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARADAPDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGTAEFNEVFFDDARTDADLVVGAPGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWANWHRNLGELAMDVIGKPGMTMPDGEFDEWQRLYLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG
>NC_018078.1|WP_003900098.1|3987865_3989389_+|3-((3aS,4S,7aS)-7a-methyl-1,-5-dioxo-octahydro-1H-inden-4-yl)propanoate--CoA-ligase
MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG
>NC_018078.1|WP_003419346.1|3989389_3990523_+|acyl-CoA-dehydrogenase
MDLNFDDETLAFQAEVREFLAANAASIPTKSYDNAEGFAQHRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYFRAGAPGRASANGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEPESGSDLASLRSTASKVDGGWLLNGQKIWSSRAPFADMGFGLFRSDPAVERHRGLTYFMFDLKAKGVTVRPIAQLGGDTGFGEIFLDDVFVPDRDVIGAPNDGWRAAMSTSSNERGMSLRSPARFLASAERLVQLWKDRGSPPEFADRVADAWIKAQAYRLQTFGTVTRLAAGGELGAESSVTKVFWSELDVHLHQTALDLRGADGELAGPWTEGLLFALGGPIYAGTNEIQRNIIAERLLGLPREKT
>NC_018078.1|WP_003900712.1|3990519_3991479_+|acyl-CoA/acyl-ACP-dehydrogenase
MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPGRKVWQQLANLGVTALGVAEKFDGLGASPVDLVVALERLGRWCVPGPVTESIAVAPILLAHDDQAERSHGLASGELIATVAMPPRVPRAVDADTAGLVLLAGDGSVTEGTPGDCHRSVDPSRRLYEVAASGQAWRAPKDVVARAYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLADVHIAIELACPLVYGAAVSLEPRDVSAAKAAASEAALLAARWALQTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL
>NC_018078.1|WP_003419352.1|3991475_3992432_+|acyl-CoA/acyl-ACP-dehydrogenase
MTPPEERQMLRETVASLVAKHAGPAAVRAAMASDRGYDESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPSPLLGTTLAELALLAAAKPDAQALTELAQGSAIGALVLDPDYVVNGDIADIVVAATSGQLTRWTRFSAQPVATMDPTRRLARLQSEETEPLCPDPGIADTAAILLAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHRMADLYVTIAAARAVVADACHAPTPTNAATARLAASEALSTAAAEGIQLHGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWESP
>NC_018078.1|WP_003419356.1|3992428_3993595_+|pyridoxal-phosphate-dependent-aminotransferase
MTDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTGWRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ
>NC_018078.1|WP_003419364.1|3993559_3994411_-|arylamine-N-acetyltransferase
MALDLTAYFDRINYRGATDPTLDVLQDLVTVHSRTIPFENLDPLLGVPVDDLSPQALADKLVLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVVWKLAPDAPLPPQTHTLLGVTFPGSGGCYLVDVGFGGQTPTSPLRLETGAVQPTTHEPYRLEDRVDGFVLQAMVRDTWQTLYEFTTQTRPQIDLKVASWYASTHPASKFVTGLTAAVITDDARWNLSGRDLAVHRAGGTEKIRLADAAAVVDTLSERFGINVADIGERGALETRIDELLARQPGADAP
>NC_018078.1|WP_003419367.1|3994395_3994662_-|hypothetical-protein
MSGADPPTRRAFGQMARAATGWVSVSGQFAVAADTCRCEGTLFAVDPETHVANHNRCDIVGRLRDERPNTLRSVRRGDEVRMATWHWI
>NC_018078.1|WP_003906149.1|3994692_3994863_-|hypothetical-protein
MSHVRYVAWLGQLSSRMANMQTLTSRSSIVADQFGEGFLVVQVDTGLQASGAVGRQ

Crispr_ID: NC_018078_13

• CRISPR_ID: NC_018078_13
• CRISPR_location: 3984992-3985369
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NC_018078_13

Consensus_repeat	Method
AACTCCGGCAGCGGCAATATCGGC	CRISPRCasFinder

spacers of NC_018078_13

>13.1|3985016|21|NC_018078|CRISPRCasFinder
AACAACAACATGGGCTTCGGC
>13.2|3985061|21|NC_018078|CRISPRCasFinder
GGCGGCAACACCGGCAACGGC
>13.3|3985106|21|NC_018078|CRISPRCasFinder
AACAACAACTTCGGCTTCGGC
>13.4|3985151|51|NC_018078|CRISPRCasFinder
ATCGGGCTCACCGGCAACAATCAGATGGGCATCAACCTGGCCGGGCTGCTG
>13.5|3985226|36|NC_018078|CRISPRCasFinder
ATCGGCAACTCCGGCACCAACAACATCGGCTTGTTC
>13.6|3985286|60|NC_018078|CRISPRCasFinder
GTCTTCAACACCGGAGCCAATACCCTGGTGCCTGGCGACCTCAACAACCTGGGCGTCGGG

CRISPR arrays and Neighbor proteins around NC_018078_13

CRISPR arrays

The CRISPR arrays of NC_018078_13

>merge|NC_018078|13|3984992-3985369|CRISPRCasFinder
AACGTGGGCCTGGGCAACATCGGCAACAACAACATGGGCTTCGGCAACACCGGCGACGCCAACACCGGCGGCGGCAACACCGGCAACGGCAACATCGGTGGCGGCAACACCGGCAACAACAACTTCGGCTTCGGCAACACCGGCAACAACAACATCGGAATCGGGCTCACCGGCAACAATCAGATGGGCATCAACCTGGCCGGGCTGCTGAACTCCGGCAGCGGCAATATCGGCATCGGCAACTCCGGCACCAACAACATCGGCTTGTTCAACTCCGGCAGCGGCAACATCGGCGTCTTCAACACCGGAGCCAATACCCTGGTGCCTGGCGACCTCAACAACCTGGGCGTCGGGAATTCCGGCAACGCCAACATCGGC

>NC_018078|13|7|3984992-3985369|CRISPRCasFinder
AACGTGGGCCTGGGCAACATCGGC	AACAACAACATGGGCTTCGGC
AACACCGGCGACGCCAACACCGGC	GGCGGCAACACCGGCAACGGC
AACATCGGTGGCGGCAACACCGGC	AACAACAACTTCGGCTTCGGC
AACACCGGCAACAACAACATCGGA	ATCGGGCTCACCGGCAACAATCAGATGGGCATCAACCTGGCCGGGCTGCTG
AACTCCGGCAGCGGCAATATCGGC	ATCGGCAACTCCGGCACCAACAACATCGGCTTGTTC
AACTCCGGCAGCGGCAACATCGGC	GTCTTCAACACCGGAGCCAATACCCTGGTGCCTGGCGACCTCAACAACCTGGGCGTCGGG
AATTCCGGCAACGCCAACATCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003419328.1|3982035_3983196_-|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl|CDD|181123
NC_018078.1|WP_003900711.1|3973613_3974528_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|236099
NC_018078.1|WP_003419364.1|3993559_3994411_-|arylamine-N-acetyltransferase	unknown	unknown	gnl|CDD|225073
NC_018078.1|WP_003900097.1|3985875_3986664_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|236110
NC_018078.1|WP_003419325.1|3978916_3980974_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|131215
NC_018078.1|WP_003419315.1|3975384_3976128_+|enoyl-CoA-hydratase-family-protein	unknown	unknown	gnl|CDD|181174
NC_018078.1|WP_003419340.1|3986660_3987818_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_018078.1|WP_003419313.1|3974550_3975330_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|236116
NC_018078.1|WP_003419346.1|3989389_3990523_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173841
NC_018078.1|WP_003906149.1|3994692_3994863_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003419352.1|3991475_3992432_+|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|224871
NC_018078.1|WP_003419324.1|3977852_3978920_+|nitronate-monooxygenase	unknown	unknown	gnl|CDD|367316
NC_018078.1|WP_003419367.1|3994395_3994662_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003900096.1|3981061_3981931_-|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|380141
NC_018078.1|WP_003900094.1|3976127_3977006_+|CoA-transferase-subunit-A	unknown	unknown	gnl|CDD|224702
NC_018078.1|WP_003900712.1|3990519_3991479_+|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|173838
NC_018078.1|WP_003419321.1|3977002_3977755_+|CoA-transferase-subunit-beta	unknown	unknown	gnl|CDD|224968
NC_018078.1|WP_003900098.1|3987865_3989389_+|3-((3aS,4S,7aS)-7a-methyl-1,-5-dioxo-octahydro-1H-inden-4-yl)propanoate--CoA-ligase	unknown	unknown	gnl|CDD|236072
NC_018078.1|WP_003419329.1|3983260_3983863_-|TetR-family-transcriptional-regulator-KstR2	unknown	unknown	gnl|CDD|366102
NC_018078.1|WP_003419356.1|3992428_3993595_+|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|235596

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003419328.1|3982035_3983196_-|acetyl-CoA-C-acetyltransferase	gnl|CDD|181123	PRK07801, PRK07801, acetyl-CoA C-acetyltransferase.	0
NC_018078.1|WP_003900711.1|3973613_3974528_-|SDR-family-oxidoreductase	gnl|CDD|236099	PRK07791, PRK07791, short chain dehydrogenase; Provisional.	7.58067e-170
NC_018078.1|WP_003419364.1|3993559_3994411_-|arylamine-N-acetyltransferase	gnl|CDD|225073	COG2162, NhoA, Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism].	1.26917e-126
NC_018078.1|WP_003900097.1|3985875_3986664_-|SDR-family-oxidoreductase	gnl|CDD|236110	PRK07831, PRK07831, SDR family oxidoreductase.	1.1239e-170
NC_018078.1|WP_003419325.1|3978916_3980974_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|131215	TIGR02160, 12-phenylacetyl-CoA_epoxidase_subunit_E, phenylacetate-CoA oxygenase/reductase, PaaK subunit. Phenylacetate-CoA oxygenase is comprised of a five gene complex responsible for the hydroxylation of phenylacetate-CoA (PA-CoA) as the second catabolic step in phenylacetic acid (PA) degradation. Although the exact function of this enzyme has not been determined, it has been shown to be required for phenylacetic acid degradation and has been proposed to function in a multicomponent oxygenase acting on phenylacetate-CoA. [Energy metabolism, Other].	6.42722e-129
NC_018078.1|WP_003419315.1|3975384_3976128_+|enoyl-CoA-hydratase-family-protein	gnl|CDD|181174	PRK07938, PRK07938, enoyl-CoA hydratase family protein.	4.18883e-166
NC_018078.1|WP_003419340.1|3986660_3987818_-|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	6.87257e-132
NC_018078.1|WP_003419313.1|3974550_3975330_-|SDR-family-oxidoreductase	gnl|CDD|236116	PRK07856, PRK07856, SDR family oxidoreductase.	1.70513e-147
NC_018078.1|WP_003419346.1|3989389_3990523_+|acyl-CoA-dehydrogenase	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	4.1115e-133
NC_018078.1|WP_003419352.1|3991475_3992432_+|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	1.28528e-32
NC_018078.1|WP_003419324.1|3977852_3978920_+|nitronate-monooxygenase	gnl|CDD|367316	pfam03060, NMO, Nitronate monooxygenase. Nitronate monooxygenase (NMO), formerly referred to as 2-nitropropane dioxygenase (NPD) (EC:1.13.11.32), is an FMN-dependent enzyme that uses molecular oxygen to oxidize (anionic) alkyl nitronates and, in the case of the enzyme from Neurospora crassa, (neutral) nitroalkanes to the corresponding carbonyl compounds and nitrite. Previously classified as 2-nitropropane dioxygenase, but it is now recognized that this was the result of the slow ionization of nitroalkanes to their nitronate (anionic) forms. The enzymes from the fungus Neurospora crassa and the yeast Williopsis saturnus var. mrakii (formerly classified as Hansenula mrakii) contain non-covalently bound FMN as the cofactor. Active towards linear alkyl nitronates of lengths between 2 and 6 carbon atoms and, with lower activity, towards propyl-2-nitronate. The enzyme from N. crassa can also utilize neutral nitroalkanes, but with lower activity. One atom of oxygen is incorporated into the carbonyl group of the aldehyde product. The reaction appears to involve the formation of an enzyme-bound nitronate radical and an a-peroxynitroethane species, which then decomposes, either in the active site of the enzyme or after release, to acetaldehyde and nitrite.	1.54808e-102
NC_018078.1|WP_003900096.1|3981061_3981931_-|DUF559-domain-containing-protein	gnl|CDD|380141	pfam18741, MTES_1575, REase_MTES_1575. Vsr REase Fold. Fused to HEPN (SWT1/Abi2 family), along with Transglutaminase and wHTH.	3.67664e-09
NC_018078.1|WP_003900094.1|3976127_3977006_+|CoA-transferase-subunit-A	gnl|CDD|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	6.07134e-74
NC_018078.1|WP_003900712.1|3990519_3991479_+|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	1.14474e-25
NC_018078.1|WP_003419321.1|3977002_3977755_+|CoA-transferase-subunit-beta	gnl|CDD|224968	COG2057, AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid metabolism].	4.05125e-63
NC_018078.1|WP_003900098.1|3987865_3989389_+|3-((3aS,4S,7aS)-7a-methyl-1,-5-dioxo-octahydro-1H-inden-4-yl)propanoate--CoA-ligase	gnl|CDD|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0
NC_018078.1|WP_003419329.1|3983260_3983863_-|TetR-family-transcriptional-regulator-KstR2	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	7.25468e-16
NC_018078.1|WP_003419356.1|3992428_3993595_+|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	5.98908e-167

Protein sequences

>NC_018078.1|WP_003419329.1|3983260_3983863_-|TetR-family-transcriptional-regulator-KstR2
MDRVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRWYRPGGPLTAQQVGQQYLAIVLGGITKEGV
>NC_018078.1|WP_003419328.1|3982035_3983196_-|acetyl-CoA-C-acetyltransferase
MTEAYVIDAVRTAVGKRGGALAGIHPVDLGALAWRGLLDRTDIDPAAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQAISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQWLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHFENEIITVETESGPFRVDEGPRESSLEKMAGLQPLVEGGRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIHHISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAWLKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQTMCEGGGTANVTIIERL
>NC_018078.1|WP_003900096.1|3981061_3981931_-|DUF559-domain-containing-protein
MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVELTARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPPRIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALANSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLIDAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRARDIERSTALLDLGWTIIRVTSELLWYRRGTFVGRVDAAMRAAGWRP
>NC_018078.1|WP_003419325.1|3978916_3980974_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MTDACQAEYAIAAMSTVEMDQAAPESAAHHPLPDPGESVPRLALPTIGIFLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISSIRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHGSLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAIVTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNRVGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAISTVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVDPITADATLVTFAVPEALRDAFRFEPGQHVTVRTDLGGQGIRRNYSICAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGTPLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKESTMFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTLRPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRPSYAGATVTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYACMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAVDYDA
>NC_018078.1|WP_003419324.1|3977852_3978920_+|nitronate-monooxygenase
MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLGILASATMTLDELAAAITKVKAVTDKPFGVNIRADAADAGDRVELMIREGVRVASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEGGGHTGPVATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAAGVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTELVEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWSQVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVLDAITHLQTASALVE
>NC_018078.1|WP_003419321.1|3977002_3977755_+|CoA-transferase-subunit-beta
MSTRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRVFETLAWGRRHVVMGANQVDRYGNQNISAFGPLQRPTRQMFGVRGSPGNTINHATSYWVGNHCKRVFVEAVDVVSGIGYDKVDPDNPAFRFVNVYRVVSNLGVFDFGGPDHSMRAVSLHPGVTPGDVRDATSFEVHDLDAAEQTRLPTDDELHLIRAVIDPKSLRDREIRS
>NC_018078.1|WP_003900094.1|3976127_3977006_+|CoA-transferase-subunit-A
MPDKRTALDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLDSPPFYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALRLDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFTTAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR
>NC_018078.1|WP_003419315.1|3975384_3976128_+|enoyl-CoA-hydratase-family-protein
MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAATHLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS
>NC_018078.1|WP_003419313.1|3974550_3975330_-|SDR-family-oxidoreductase
MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSANK
>NC_018078.1|WP_003900711.1|3973613_3974528_-|SDR-family-oxidoreductase
MGLVDGRVVIVTGAGGGIGRAHALAFAAEGARVVVNDIGVGLDGSPASGGSAAQDVVDEILAAGGQAVADGSDISDWDQAANLIQAAVETYGGVDVLVNNAGIVRDRMIANTSEEEFDAVIAVHLKGHFATMRHAASHWRGLSKAGKAPKDIDARIINTSSGAGLQGSVGQGNYSAAKAGIAALTLVGAAEMRRYGVTVNAIAPAARTRMTETVFAEMMAKPQEGFDAMAPENVSPLVVWLGSAESRDVTGKVFEVEGGIIRVAEGWAHGPQVDKGVKWDPAELGPVVSDLLAKSRPPVPVYGA
>NC_018078.1|WP_003900097.1|3985875_3986664_-|SDR-family-oxidoreductase
MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVVISDHHERRLGETAAELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGRLDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAPHGGVIVNNASVLGWRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINAVSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIAFLASDYSSYLTGEVISVSCQHP
>NC_018078.1|WP_003419340.1|3986660_3987818_-|acyl-CoA-dehydrogenase
MQDVEEFRAQVRGWLADNLAGEFAALKGLGGPGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARADAPDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGTAEFNEVFFDDARTDADLVVGAPGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWANWHRNLGELAMDVIGKPGMTMPDGEFDEWQRLYLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG
>NC_018078.1|WP_003900098.1|3987865_3989389_+|3-((3aS,4S,7aS)-7a-methyl-1,-5-dioxo-octahydro-1H-inden-4-yl)propanoate--CoA-ligase
MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG
>NC_018078.1|WP_003419346.1|3989389_3990523_+|acyl-CoA-dehydrogenase
MDLNFDDETLAFQAEVREFLAANAASIPTKSYDNAEGFAQHRYWDRVLFDAGLSVITWPAKYGGRDAPLLHWIVFEEEYFRAGAPGRASANGTSMLAPTLFAHGTAEQLDRILPKMASGEQIWAQAWSEPESGSDLASLRSTASKVDGGWLLNGQKIWSSRAPFADMGFGLFRSDPAVERHRGLTYFMFDLKAKGVTVRPIAQLGGDTGFGEIFLDDVFVPDRDVIGAPNDGWRAAMSTSSNERGMSLRSPARFLASAERLVQLWKDRGSPPEFADRVADAWIKAQAYRLQTFGTVTRLAAGGELGAESSVTKVFWSELDVHLHQTALDLRGADGELAGPWTEGLLFALGGPIYAGTNEIQRNIIAERLLGLPREKT
>NC_018078.1|WP_003900712.1|3990519_3991479_+|acyl-CoA/acyl-ACP-dehydrogenase
MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPGRKVWQQLANLGVTALGVAEKFDGLGASPVDLVVALERLGRWCVPGPVTESIAVAPILLAHDDQAERSHGLASGELIATVAMPPRVPRAVDADTAGLVLLAGDGSVTEGTPGDCHRSVDPSRRLYEVAASGQAWRAPKDVVARAYEFGALATAAQLVGAGQALLEAAVNYAKQRTQFGRAIGSYQAIKHKLADVHIAIELACPLVYGAAVSLEPRDVSAAKAAASEAALLAARWALQTHGAIGFTCEHDLSLWLLRVQALHSAWGTPQEHRRRVLEAL
>NC_018078.1|WP_003419352.1|3991475_3992432_+|acyl-CoA/acyl-ACP-dehydrogenase
MTPPEERQMLRETVASLVAKHAGPAAVRAAMASDRGYDESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPSPLLGTTLAELALLAAAKPDAQALTELAQGSAIGALVLDPDYVVNGDIADIVVAATSGQLTRWTRFSAQPVATMDPTRRLARLQSEETEPLCPDPGIADTAAILLAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHRMADLYVTIAAARAVVADACHAPTPTNAATARLAASEALSTAAAEGIQLHGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWESP
>NC_018078.1|WP_003419356.1|3992428_3993595_+|pyridoxal-phosphate-dependent-aminotransferase
MTDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTGWRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ
>NC_018078.1|WP_003419364.1|3993559_3994411_-|arylamine-N-acetyltransferase
MALDLTAYFDRINYRGATDPTLDVLQDLVTVHSRTIPFENLDPLLGVPVDDLSPQALADKLVLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVVWKLAPDAPLPPQTHTLLGVTFPGSGGCYLVDVGFGGQTPTSPLRLETGAVQPTTHEPYRLEDRVDGFVLQAMVRDTWQTLYEFTTQTRPQIDLKVASWYASTHPASKFVTGLTAAVITDDARWNLSGRDLAVHRAGGTEKIRLADAAAVVDTLSERFGINVADIGERGALETRIDELLARQPGADAP
>NC_018078.1|WP_003419367.1|3994395_3994662_-|hypothetical-protein
MSGADPPTRRAFGQMARAATGWVSVSGQFAVAADTCRCEGTLFAVDPETHVANHNRCDIVGRLRDERPNTLRSVRRGDEVRMATWHWI
>NC_018078.1|WP_003906149.1|3994692_3994863_-|hypothetical-protein
MSHVRYVAWLGQLSSRMANMQTLTSRSSIVADQFGEGFLVVQVDTGLQASGAVGRQ

Crispr_ID: NC_018078_14

• CRISPR_ID: NC_018078_14
• CRISPR_location: 4098263-4098351
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018078_14

Consensus_repeat	Method
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CRISPRCasFinder

spacers of NC_018078_14

>14.1|4098294|27|NC_018078|CRISPRCasFinder
CGAGGAGGAGCCGAGCAATCGAACCGA

CRISPR arrays and Neighbor proteins around NC_018078_14

CRISPR arrays

The CRISPR arrays of NC_018078_14

>merge|NC_018078|14|4098263-4098351|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCCCGAGGAGGAGCCGAGCAATCGAACCGAGCTCGGCGACGATGCGGGCCGGATGACGGCC

>NC_018078|14|8|4098263-4098351|CRISPRCasFinder
GCTCGGCGACGATGCGGGCCGGATGACGGCC	CGAGGAGGAGCCGAGCAATCGAACCGA
GCTCGGCGACGATGCGGGCCGGATGACGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018078.1|WP_003900733.1|4089616_4091263_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_018078.1|WP_003899626.1|4088849_4089620_-|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003419701.1|4092115_4093042_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_018078.1|WP_003900734.1|4099906_4101100_-|acid-resistance-serine-protease-MarP	unknown	unknown	gnl|CDD|379142
NC_018078.1|WP_014297598.1|4085680_4086733_-|septum-site-determining-protein-Ssd	unknown	unknown	gnl|CDD|274798
NC_018078.1|WP_003419721.1|4102058_4102742_-|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NC_018078.1|WP_003899624.1|4084520_4085684_-|TadA-family-conjugal-transfer-associated-ATPase	unknown	unknown	gnl|CDD|200328
NC_018078.1|WP_003899629.1|4093043_4094669_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173853
NC_018078.1|WP_003419728.1|4104062_4104737_+|cAMP-activated-global-transcriptional-regulator-CRP	unknown	unknown	gnl|CDD|223736
NC_018078.1|WP_003419733.1|4105643_4106099_-|RidA-family-protein	unknown	unknown	gnl|CDD|100006
NC_018078.1|WP_003419710.1|4098411_4098930_+|phage-holin-family-protein	unknown	unknown	gnl|CDD|377816
NC_018078.1|WP_003899628.1|4091259_4092123_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_018078.1|WP_003419718.1|4101105_4101927_-|CoA-pyrophosphatase	unknown	unknown	gnl|CDD|239518
NC_018078.1|WP_003419731.1|4104842_4105637_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293836
NC_018078.1|WP_003419712.1|4098930_4099914_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_018078.1|WP_003419708.1|4097367_4098066_-|protease	unknown	unknown	unknown
NC_018078.1|WP_003899635.1|4103586_4103964_+|hypothetical-protein	unknown	unknown	unknown
NC_018078.1|WP_003419689.1|4087231_4088095_+|HAD-IB-family-hydrolase	unknown	unknown	gnl|CDD|273654
NC_018078.1|WP_003419724.1|4102741_4103479_-|endonuclease-III	unknown	unknown	gnl|CDD|223255
NC_018078.1|WP_003899631.1|4095376_4097332_+|acetate--CoA-ligase	unknown	unknown	gnl|CDD|234677

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018078.1|WP_003900733.1|4089616_4091263_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_018078.1|WP_003419721.1|4102058_4102742_-|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.72736e-22
NC_018078.1|WP_003419701.1|4092115_4093042_-|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.57934e-99
NC_018078.1|WP_003900734.1|4099906_4101100_-|acid-resistance-serine-protease-MarP	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.86888e-19
NC_018078.1|WP_014297598.1|4085680_4086733_-|septum-site-determining-protein-Ssd	gnl|CDD|274798	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein. Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins (see ). Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.	2.65548e-91
NC_018078.1|WP_003419728.1|4104062_4104737_+|cAMP-activated-global-transcriptional-regulator-CRP	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.11707e-55
NC_018078.1|WP_003419724.1|4102741_4103479_-|endonuclease-III	gnl|CDD|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	2.16645e-106
NC_018078.1|WP_003899629.1|4093043_4094669_-|ABC-transporter-substrate-binding-protein	gnl|CDD|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.73988e-122
NC_018078.1|WP_003419710.1|4098411_4098930_+|phage-holin-family-protein	gnl|CDD|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	8.41555e-32
NC_018078.1|WP_003899628.1|4091259_4092123_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.77559e-81
NC_018078.1|WP_003419718.1|4101105_4101927_-|CoA-pyrophosphatase	gnl|CDD|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	1.20605e-47
NC_018078.1|WP_003419731.1|4104842_4105637_-|MBL-fold-metallo-hydrolase	gnl|CDD|293836	cd16278, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	3.29322e-75
NC_018078.1|WP_003419712.1|4098930_4099914_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.34553e-25
NC_018078.1|WP_003899624.1|4084520_4085684_-|TadA-family-conjugal-transfer-associated-ATPase	gnl|CDD|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	1.05849e-164
NC_018078.1|WP_003419689.1|4087231_4088095_+|HAD-IB-family-hydrolase	gnl|CDD|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	5.37865e-86
NC_018078.1|WP_003419733.1|4105643_4106099_-|RidA-family-protein	gnl|CDD|100006	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	7.62827e-68
NC_018078.1|WP_003899631.1|4095376_4097332_+|acetate--CoA-ligase	gnl|CDD|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0

Protein sequences

>NC_018078.1|WP_003419708.1|4097367_4098066_-|protease
MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGDTMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGNDGLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCGVTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCITKYIPLHTPAVVMSINADLADINAKNRPGAGFVPVPA
>NC_018078.1|WP_003899631.1|4095376_4097332_+|acetate--CoA-ligase
MSESTPEVSSSYPPPAHFAEHANARAELYREAEEDRLAFWAKQANRLSWTTPFTEVLDWSGAPFAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPDCSVEHVLVVRRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGKPKGIMHTSGGYLTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPTLIRMFMKWGREIPDSHDLSSLRLLGSVGEPINPEAWRWYRDVIGGGRTPLVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGAQHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTDETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISPIARPRDVHVVPELPKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIRAAK
>NC_018078.1|WP_003899629.1|4093043_4094669_-|ABC-transporter-substrate-binding-protein
MVRQMRAALAALATGLLVLAPVAGCGGGVLSPDVVLVNGGEPPNPLIPTGTNDSNGGRIIDRLFAGLMSYDAVGKPSLEVAQSIESADNVNYRITVKPGWKFTDGSPVTAHSFVDAWNYGALSTNAQLQQHFFSPIEGFDDVAGAPGDKSRTTMSGLRVVNDLEFTVRLKAPTIDFTLRLGHSSFYPLPDSAFRDMAAFGRNPIGNGPYKLADGPAGPAWEHNVRIDLVPNPDYHGNRKPRNKGLRFEFYANLDTAYADLLSGNLDVLDTIPPSALTVYQRDLGDHATSGPAAINQTLDTPLRLPHFGGEEGRLRRLALSAAINRPQICQQIFAGTRSPARDFTARSLPGFDPNLPGNEVLDYDPQRARRLWAQADAISPWSGRYAIAYNADAGHRDWVDAVANSIKNVLGIDAVAAPQPTFAGFRTQITNRAIDSAFRAGWRGDYPSMIEFLAPLFTAGAGSNDVGYINPEFDAALAAAEAAPTLTESHELVNDAQRILFHDMPVVPLWDYISVVGWSSQVSNVTVTWNGLPDYENIVKA
>NC_018078.1|WP_003419701.1|4092115_4093042_-|ABC-transporter-permease
MGWYVARRVAVMVPVFLGATLLIYGMVFLLPGDPVAALAGDRPLTPAVAAQLRSHYHLDDPFLVQYLRYLGGILHGDLGRAYSGLPVSAVLAHAFPVTIRLALIALAVEAVLGIGFGVIAGLRQGGIFDSAVLVTGLVIIAIPIFVLGFLAQFLFGVQLEIAPVTVGERASVGRLLLPGIVLGAMSFAYVVRLTRSAVAANAHADYVRTATAKGLSRPRVVTVHILRNSLIPVVTFLGADLGALMGGAIVTEGIFNIHGVGGVLYQAVTRQETPTVVSIVTVLVLIYLITNLLVDLLYAALDPRIRYG
>NC_018078.1|WP_003899628.1|4091259_4092123_-|ABC-transporter-permease
MAEHTGFWLDAWRGLRRRPKFVIAAALILLILVVAAFPSLFTAADPTYADPSQSMLAPSAAHWFGTDLQGHDIYSRTVYGARASVTVGLGATLAVFVVGGALGALAGFYGSWIDAVVSRVTDVFLGLPLLLAAIVLMQVMHHRTVWTVIAILALFGWPQVARIARGAVLEVRASDYVLAAKALGLNRFQILLRHALPNAVGPVIAVATVALGIFIVTEATLSYLGVGLPTSVVSWGGDINVAQTRLRSGSPILFYPAGALAITVLAFMMMGDALRDALDPASRAWRA
>NC_018078.1|WP_003900733.1|4089616_4091263_-|ABC-transporter-ATP-binding-protein
MSVPAAPLLSVEGLEVTFGTDAPAVCGVDLAVRSGQTVAVVGESGSGKSTTAAAILGLLPAGGRITAGRVVFDGRDITGADAKRLRSIRGREIGYVPQDPMTNLNPVWKVGFQVTEALRANTDGRAARRRAVELLAEAGLPDPAKQAGRYPHQLSGGMCQRALIAIGLAGRPRLLIADEPTSALDVTVQRQVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQSILQSPQHEYTRRLVAAAPSLTARSRRPPESRSRATTQAGDILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTLAIVGESGSGKSTLARMVLGLLQPTSGTVVFDGTYDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHHVGDRRQRQRAVRELVDQVALPSSILGRRPRELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLVQAQILDLLADLQADLGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQLLQAIPGAPSAPRKVGNL
>NC_018078.1|WP_003899626.1|4088849_4089620_-|hypothetical-protein
MTVDPLAPLMELPGVAAASDRVRDALSRVHRHRANLRGWPVAAAEASLRAARASSVLDGGPARLHDAGAPTSGKPALSDPVFAGALRVGQALEGGAGPVVGVWRRAPLQALARLHMLAAADQVDDDRLGRPRSDADVGPRLELLADVVTHPTLASAPVVAAVAHGELLTLRPFGCADGVVARAVSRLVTIATGLDPHGLGVPEVIWMRQPAEYHDAARRFAGGTPDGVAGWLLLCCGAMLDGAREALSIAESLSPG
>NC_018078.1|WP_003419689.1|4087231_4088095_+|HAD-IB-family-hydrolase
MTVSDSPAQRQTPPQTPGGTAPRARTAAFFDLDKTIIAKSSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRTHLTNMCAGWDVAQVRSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVGPIARALGATHAMATRMIVEDGKYTGEVAFYCYGEGKAQAIRELAASEGYPLEHCYAYSDSITDLPMLEAVGHASVVNPDRGLRKEASVRGWPVLSFSRPVSLRDRIPAPSAAAIATTAAVGISALAAGAVTYALLRRFAFQP
>NC_018078.1|WP_014297598.1|4085680_4086733_-|septum-site-determining-protein-Ssd
MLTDPGLRDELDRVAAAVGVRVVHLGGRHPVSRKTWSAAAAVVLDHAAADRCGRLALPRRTHVSVLTGTEAATATWAAAITVGAQHVLRMPEQEGELVRELAEAAESARDDGICGAVVAVIGGRGGAGASLFAVALAQAAADALLVDLDPWAGGIDLLVGGETAPGLRWPDLALQGGRLNWSAVRAALPRPRGISVLSGTRRGYELDAGPVDAVIDAGRRGGVTVVCDLPRRLTDATQAALDAADLVVLVSPCDVRACAAAATMAPVLTAINPNLGLVVRGSSPGGLRAAEVADVAGVPLLASMRAQPRLAEQLEHGGLRLRRRSVLASAARRVLGVLPRAGSGRHGRAA
>NC_018078.1|WP_003899624.1|4084520_4085684_-|TadA-family-conjugal-transfer-associated-ATPase
MTGSLIERVRERLASESGPLRPSVVAAAIRAESGGMLGDTEVLANLRVLQTELTGAGILEPLLSADGTTDVLVTAPDSVWVDDGNGLRRSQIRFADESAVRRLAQRLALAAGRRLDDAQPWVDGQLTGIGVGGFAVRLHAVLPPVATQGTCLSLRVLRPATQDLAALAAAGAIDPAAAALVADIVTARLAFLVCGGTGAGKTTLLAAMLGAVSPDERIVCVEDAAELAPRHPHLVKLVARRANVEGIGEVTVRQLVRQALRMRPDRIVVGEVRGAEVVDLLAALNTGHEGGAGTVHANNPGEVPARMEALGALGGLDRAALHSQLAAAVQVLLHVARDRAGRRRLAEIAVLRQAEGRVQAVTVWHADRGMSDDAAALHDLLRSRASA
>NC_018078.1|WP_003419710.1|4098411_4098930_+|phage-holin-family-protein
MSKIDRKNGVPSTLTTIPLADPHAGPAEPSIGDLIKDATTQMSTLVRAEVELARAEITRDVKKGLTGSVFFISSLVVGFYSTFFFFFFVAELLDTWIWRWVAFLLVFAIMVVVTAVLALLGFLKVRRIRGPRQTIASVKETRTALTPGHDKTPVTPKPVTSDRATPVDPSGW
>NC_018078.1|WP_003419712.1|4098930_4099914_+|alpha/beta-hydrolase
MAAPDPSMTRIAGPWRHLDVHANGIRFHVVEAVPSGQPEGPDAATPPMQPALARPLVILLHGFGSFWWSWRHQLCGLTGARVVAVDLRGYGGSDKPPRGYDGWTLAGDTAGLIRALGHPSATLVGHADGGLACWTTALLHSRLVRAIALISSPHPAALRRSTLTRRDQRHALLPTLLRYQLPIWPERLLTRNNAAEIERLVRARGCAKWLASEDFSQAIDHLRQAIQIPAAAHCALEYQRWAVRSQLRSEGRRFIRAMTQQLGMPLLHLRGDADPYVLADPVERTQRYAPHGRYISIAGAGHFSHEEAPEEVNRHLMRFLEQVHQLS
>NC_018078.1|WP_003900734.1|4099906_4101100_-|acid-resistance-serine-protease-MarP
MTPSQWLDIAVLAVAFIAAISGWRAGALGSMLSFGGVLLGATAGVLLAPHIVSQISAPRAKLFAALFLILALVVVGEVAGVVLGRAVRGAIRNRPIRLIDSVIGVGVQLVVVLTAAWLLAMPLTQSKEQPELAAAVKGSRVLARVNEAAPTWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPALVNNPVVAATEPSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTVYAGDKPFEATVVSYDPSVDVAILAVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDSGGPLIDLNGQVLGVVFGAAIDDAETGFVLTAGEVAGQLAKIGATQPVGTGACVS
>NC_018078.1|WP_003419718.1|4101105_4101927_-|CoA-pyrophosphatase
MSAGGTPLQAGATPTGSRGTVALRPDAGPSWLRPLVDNVGQIPDAYRRRLPADVLAMVTAAGAVSAMTSSRRDHREAAVLVLFSGPEAGPGDGGVPDDADLLLTVRASTLRHHAGQAAFPGGVVDPADDGPVATALREANEETGIDPSRLHPLATMERTFIAPSRFHVVPVLAYSPDPGPVAVVNEAETAIVARVPVRAFINPANRLMVYRRPHTRRWAGPAFLLNQMLVWGFTGQVISAVLDVAGWAQPWDTGDIRELDAAMVLIDDESDPR
>NC_018078.1|WP_003419721.1|4102058_4102742_-|TlpA-family-protein-disulfide-reductase
MPSLPTTPAETAMTTLTGKTRWTIAILAVVAALMAALVAQLHDYSASSTISQRPAPREHRDGDTPEALAWSRQRANLPPCPAAGNGPGAAALRGVVVVCAGDGSAVDVARALAGRRVVINLWAHWCAPCMTELPVMAEYQRRVGPAVLVVTVHQGQNEAAALSRLADLGVRLPTLQDDRRRVAAALRVANVMPATVVLRPDGSVAQTLPRAFGSADEIVAAVGNDAG
>NC_018078.1|WP_003419724.1|4102741_4103479_-|endonuclease-III
MPGRWSAETRLALVRRARRMNRALAQAFPHVYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPLVQGPETDHLLALAGL
>NC_018078.1|WP_003899635.1|4103586_4103964_+|hypothetical-protein
MFTLLVSWLLVACVPGLLMLATLGLGRLERFLARDTVTATDVAEFLEQAEAVDVHTLARNGMPEALDYLHRRQARRITDSPPLGSGAGPRYAGPLFVTDLDSPVEPPRHGQPNPQFRTARHANHV
>NC_018078.1|WP_003419728.1|4104062_4104737_+|cAMP-activated-global-transcriptional-regulator-CRP
MDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIADRPEISEQLLRVLARRLRRTNNNLADLIFTDVPGRVAKQLLQLAQRFGTQEGGALRVTHDLTQEEIAQLVGASRETVNKALADFAHRGWIRLEGKSVLISDSERLARRAR
>NC_018078.1|WP_003419731.1|4104842_4105637_-|MBL-fold-metallo-hydrolase
MSKTAESLTHPAYGQLRAVTDTASVLLADNPGLLTLDGTNTWVLRGPLSDELVVVDPGPDDDEHLARVAALGRIALVLISHRHGDHTSGIDKLVALTGAPVRAADPQFLRRDGETLTDGEVIDVAGLTITVLATPGHTADSLSFVLDDAVLTADTVLGCGTTVIDKEDGSLADYLESLHRLRGLGRRTVLPGHGPDLLDLEAIASGYLLHRHERLEQIRAALRDLGDDATVREVVEHVYLDVDEKLWNAAEWSVQAQLDYLRTR
>NC_018078.1|WP_003419733.1|4105643_4106099_-|RidA-family-protein
MSAKARLGQLGVTLPQVAAPLAAYVPAVRTGNLVYTAGQLPLEAGKLVRTGKLGADVNPEEGKTLARICALNALAAVDSLVDLDAVTRVVKVVGFVASAPGFHGQPSVINGASDLLAEVFGDSGAHARSAVGVSELPLDAPVEVELIVEVG

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_018078_1	1.2|334827|17|NC_018078|PILER-CR	334827-334843	17	NC_018078.1	841838-841854	1	0.941
NC_018078_1	1.2|334827|17|NC_018078|PILER-CR	334827-334843	17	NC_018078.1	1610082-1610098	1	0.941
NC_018078_1	1.2|334827|17|NC_018078|PILER-CR	334827-334843	17	NC_018078.1	1991798-1991814	1	0.941
NC_018078_1	1.2|334827|17|NC_018078|PILER-CR	334827-334843	17	NC_018078.1	3198399-3198415	1	0.941
NC_018078_1	1.2|334827|17|NC_018078|PILER-CR	334827-334843	17	NC_018078.1	3222118-3222134	1	0.941
NC_018078_1	1.2|334827|17|NC_018078|PILER-CR	334827-334843	17	NC_018078.1	4023193-4023209	1	0.941
NC_018078_10	10.3|2360638|21|NC_018078|CRT	2360638-2360658	21	NC_018078.1	2059080-2059100	1	0.952
NC_018078_10	10.3|2360638|21|NC_018078|CRT	2360638-2360658	21	NC_018078.1	2922552-2922572	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	1490916-1490936	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3220359-3220379	1	0.952
NC_018078_13	13.3|3985106|21|NC_018078|CRISPRCasFinder	3985106-3985126	21	NC_018078.1	3149121-3149141	1	0.952
NC_018078_3	3.5|369608|42|NC_018078|CRISPRCasFinder	369608-369649	42	NC_018078.1	377669-377710	2	0.952
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NC_018078.1	376484-376516	2	0.939
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	NC_018078.1	675404-675439	2	0.944
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	NC_018078.1	1991501-1991536	2	0.944
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	NC_018078.1	3198083-3198118	2	0.944
NC_018078_10	10.3|2360638|21|NC_018078|CRT	2360638-2360658	21	NC_018078.1	2922711-2922731	2	0.905
NC_018078_10	10.3|2360638|21|NC_018078|CRT	2360638-2360658	21	NC_018078.1	3250219-3250239	2	0.905
NC_018078_10	10.5|2360737|21|NC_018078|CRT	2360737-2360757	21	NC_018078.1	3320714-3320734	2	0.905
NC_018078_10	10.5|2360737|21|NC_018078|CRT	2360737-2360757	21	NC_018078.1	3797668-3797688	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	334750-334770	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	339828-339848	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	528473-528493	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	673723-673743	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	837943-837963	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	840687-840707	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	927861-927881	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	1490916-1490936	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	2776457-2776477	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	3220359-3220379	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	3735585-3735605	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	3798001-3798021	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	3932243-3932263	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_018078.1	3932288-3932308	2	0.905
NC_018078_13	13.1|3985016|21|NC_018078|CRISPRCasFinder	3985016-3985036	21	NC_018078.1	429972-429992	2	0.905
NC_018078_13	13.1|3985016|21|NC_018078|CRISPRCasFinder	3985016-3985036	21	NC_018078.1	430002-430022	2	0.905
NC_018078_13	13.1|3985016|21|NC_018078|CRISPRCasFinder	3985016-3985036	21	NC_018078.1	434286-434306	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	132425-132445	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	336519-336539	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	339504-339524	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	528473-528493	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	673453-673473	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	673462-673482	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	673513-673533	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	673522-673542	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	673633-673653	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	674356-674376	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	837943-837963	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	838951-838971	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	840597-840617	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	841932-841952	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	927861-927881	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	1453658-1453678	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	1490814-1490834	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	1611814-1611834	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	2333694-2333714	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	2334165-2334185	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	2432462-2432482	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	2776457-2776477	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	2780299-2780319	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	2795026-2795046	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3026754-3026774	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3223124-3223144	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3223178-3223198	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3319706-3319726	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3443079-3443099	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3735086-3735106	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3735693-3735713	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3735711-3735731	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3735762-3735782	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3735813-3735833	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3735957-3735977	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3736887-3736907	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3737064-3737084	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3737454-3737474	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3776889-3776909	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3916762-3916782	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3916858-3916878	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3917854-3917874	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3917863-3917883	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3917872-3917892	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3917881-3917901	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3917890-3917910	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3918661-3918681	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3918856-3918876	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3924759-3924779	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3929609-3929629	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3930308-3930328	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3930950-3930970	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3932171-3932191	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3932288-3932308	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3932735-3932755	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_018078.1	3936163-3936183	2	0.905
NC_018078_13	13.3|3985106|21|NC_018078|CRISPRCasFinder	3985106-3985126	21	NC_018078.1	429972-429992	2	0.905
NC_018078_13	13.3|3985106|21|NC_018078|CRISPRCasFinder	3985106-3985126	21	NC_018078.1	430002-430022	2	0.905
NC_018078_13	13.3|3985106|21|NC_018078|CRISPRCasFinder	3985106-3985126	21	NC_018078.1	434286-434306	2	0.905

1. spacer 1.2|334827|17|NC_018078|PILER-CR matches to position: 841838-841854, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

2. spacer 1.2|334827|17|NC_018078|PILER-CR matches to position: 1610082-1610098, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

3. spacer 1.2|334827|17|NC_018078|PILER-CR matches to position: 1991798-1991814, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

4. spacer 1.2|334827|17|NC_018078|PILER-CR matches to position: 3198399-3198415, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgctggcgccgccgcca	Protospacer
**************.**

5. spacer 1.2|334827|17|NC_018078|PILER-CR matches to position: 3222118-3222134, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

6. spacer 1.2|334827|17|NC_018078|PILER-CR matches to position: 4023193-4023209, mismatch: 1, identity: 0.941

cgctggcgccgccgtca	CRISPR spacer
cgccggcgccgccgtca	Protospacer
***.*************

7. spacer 10.3|2360638|21|NC_018078|CRT matches to position: 2059080-2059100, mismatch: 1, identity: 0.952

gccggcgggctgctctacggc	CRISPR spacer
gccggcgggctgctgtacggc	Protospacer
************** ******

8. spacer 10.3|2360638|21|NC_018078|CRT matches to position: 2922552-2922572, mismatch: 1, identity: 0.952

gccggcgggctgctctacggc	CRISPR spacer
gccggcgggctgctgtacggc	Protospacer
************** ******

9. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 1490916-1490936, mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacgccggcaacggc	Protospacer
*********.***********

10. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3220359-3220379, mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacgccggcaacggc	Protospacer
*********.***********

11. spacer 13.3|3985106|21|NC_018078|CRISPRCasFinder matches to position: 3149121-3149141, mismatch: 1, identity: 0.952

aacaacaacttcggcttcggc	CRISPR spacer
aacaacaacttcgggttcggc	Protospacer
************** ******

12. spacer 3.5|369608|42|NC_018078|CRISPRCasFinder matches to position: 377669-377710, mismatch: 2, identity: 0.952

ccggtgcccgagttgaagaacccgatgtttccgctgccggag	CRISPR spacer
ccggtgcccgagttgaacaacccgacgtttccgctgccggag	Protospacer
***************** *******.****************

13. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to position: 376484-376516, mismatch: 2, identity: 0.939

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
aggctgccgaacccgatctggccgctgccggtg	Protospacer
********** *************.********

14. spacer 6.17|927250|36|NC_018078|CRT matches to position: 675404-675439, mismatch: 2, identity: 0.944

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gctgatgggcaacggcggcaacggcggggccggcgg	Protospacer
****** ***********.*****************

15. spacer 6.17|927250|36|NC_018078|CRT matches to position: 1991501-1991536, mismatch: 2, identity: 0.944

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gctgatcggcaacggcggcaacggcggtgccggcgg	Protospacer
******************.******** ********

16. spacer 6.17|927250|36|NC_018078|CRT matches to position: 3198083-3198118, mismatch: 2, identity: 0.944

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gctgatcggcaacggcggccacggcggggccggcgg	Protospacer
******************. ****************

17. spacer 10.3|2360638|21|NC_018078|CRT matches to position: 2922711-2922731, mismatch: 2, identity: 0.905

gccggcgggctgctctacggc	CRISPR spacer
gccggcgggctgctgttcggc	Protospacer
************** * ****

18. spacer 10.3|2360638|21|NC_018078|CRT matches to position: 3250219-3250239, mismatch: 2, identity: 0.905

gccggcgggctgctctacggc	CRISPR spacer
gccggcggcctggtctacggc	Protospacer
******** *** ********

19. spacer 10.5|2360737|21|NC_018078|CRT matches to position: 3320714-3320734, mismatch: 2, identity: 0.905

aatggcgggctgctgttcggc	CRISPR spacer
aacggcgggctgctattcggc	Protospacer
**.***********.******

20. spacer 10.5|2360737|21|NC_018078|CRT matches to position: 3797668-3797688, mismatch: 2, identity: 0.905

aatggcgggctgctgttcggc	CRISPR spacer
aacggcggcctgctgttcggc	Protospacer
**.***** ************

21. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 334750-334770, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacggcggcagcggc	Protospacer
*********. **********

22. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 339828-339848, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacggcggcagcggc	Protospacer
*********. **********

23. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 528473-528493, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcgccaacaccggcatcggc	Protospacer
**** *********** ****

24. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 673723-673743, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacggcggcagcggc	Protospacer
*********. **********

25. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 837943-837963, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacgccggcatcggc	Protospacer
*********.****** ****

26. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 840687-840707, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacggcggcagcggc	Protospacer
*********. **********

27. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 927861-927881, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacgccggcaccggc	Protospacer
*********.****** ****

28. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 1490916-1490936, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacgccggcaacggc	Protospacer
*********.******.****

29. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 2776457-2776477, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaaccccggcaccggc	Protospacer
********* ****** ****

30. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 3220359-3220379, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacgccggcaacggc	Protospacer
*********.******.****

31. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 3735585-3735605, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacggcggcagcggc	Protospacer
*********. **********

32. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 3798001-3798021, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacggcggcagcggc	Protospacer
*********. **********

33. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 3932243-3932263, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacggcggcagcggc	Protospacer
*********. **********

34. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to position: 3932288-3932308, mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacagcggcaccggc	Protospacer
********** ***** ****

35. spacer 13.1|3985016|21|NC_018078|CRISPRCasFinder matches to position: 429972-429992, mismatch: 2, identity: 0.905

aacaacaacatgggcttcggc	CRISPR spacer
aacaacaacatcggcatcggc	Protospacer
*********** *** *****

36. spacer 13.1|3985016|21|NC_018078|CRISPRCasFinder matches to position: 430002-430022, mismatch: 2, identity: 0.905

aacaacaacatgggcttcggc	CRISPR spacer
aactacaacatcggcttcggc	Protospacer
*** ******* *********

37. spacer 13.1|3985016|21|NC_018078|CRISPRCasFinder matches to position: 434286-434306, mismatch: 2, identity: 0.905

aacaacaacatgggcttcggc	CRISPR spacer
aactacaacatcggcttcggc	Protospacer
*** ******* *********

38. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 132425-132445, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggaaacgccggcaacggc	Protospacer
***** ***.***********

39. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 336519-336539, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

40. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 339504-339524, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

41. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 528473-528493, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcgccaacaccggcatcggc	Protospacer
**** *********** ****

42. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 673453-673473, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

43. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 673462-673482, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

44. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 673513-673533, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

45. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 673522-673542, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

46. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 673633-673653, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

47. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 674356-674376, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

48. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 837943-837963, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacgccggcatcggc	Protospacer
*********.****** ****

49. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 838951-838971, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

50. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 840597-840617, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

51. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 841932-841952, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

52. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 927861-927881, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacgccggcaccggc	Protospacer
*********.****** ****

53. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 1453658-1453678, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

54. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 1490814-1490834, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

55. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 1611814-1611834, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcgacagcggcaacggc	Protospacer
******.*** **********

56. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 2333694-2333714, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

57. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 2334165-2334185, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

58. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 2432462-2432482, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

59. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 2776457-2776477, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaaccccggcaccggc	Protospacer
********* ****** ****

60. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 2780299-2780319, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

61. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 2795026-2795046, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

62. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3026754-3026774, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

63. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3223124-3223144, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

64. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3223178-3223198, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

65. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3319706-3319726, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacgccggccacggc	Protospacer
*********.***** *****

66. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3443079-3443099, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

67. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3735086-3735106, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

68. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3735693-3735713, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaactccggcaacagc	Protospacer
********* ********.**

69. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3735711-3735731, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

70. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3735762-3735782, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcagcgccggcaacggc	Protospacer
*******.*.***********

71. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3735813-3735833, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

72. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3735957-3735977, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

73. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3736887-3736907, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

74. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3737064-3737084, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

75. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3737454-3737474, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

76. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3776889-3776909, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

77. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3916762-3916782, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

78. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3916858-3916878, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

79. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3917854-3917874, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

80. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3917863-3917883, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

81. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3917872-3917892, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

82. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3917881-3917901, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

83. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3917890-3917910, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

84. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3918661-3918681, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacgccggcgacggc	Protospacer
*********.*****.*****

85. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3918856-3918876, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

86. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3924759-3924779, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaccaacggcaacggc	Protospacer
******* ** **********

87. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3929609-3929629, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

88. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3930308-3930328, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

89. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3930950-3930970, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

90. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3932171-3932191, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

91. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3932288-3932308, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacagcggcaccggc	Protospacer
********** ***** ****

92. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3932735-3932755, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacggcggcaacggc	Protospacer
*********. **********

93. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to position: 3936163-3936183, mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaccaacggcaacggc	Protospacer
******* ** **********

94. spacer 13.3|3985106|21|NC_018078|CRISPRCasFinder matches to position: 429972-429992, mismatch: 2, identity: 0.905

aacaacaacttcggcttcggc	CRISPR spacer
aacaacaacatcggcatcggc	Protospacer
********* ***** *****

95. spacer 13.3|3985106|21|NC_018078|CRISPRCasFinder matches to position: 430002-430022, mismatch: 2, identity: 0.905

aacaacaacttcggcttcggc	CRISPR spacer
aactacaacatcggcttcggc	Protospacer
*** ***** ***********

96. spacer 13.3|3985106|21|NC_018078|CRISPRCasFinder matches to position: 434286-434306, mismatch: 2, identity: 0.905

aacaacaacttcggcttcggc	CRISPR spacer
aactacaacatcggcttcggc	Protospacer
*** ***** ***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	200082-200102	0	1.0
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP039644	Azospirillum sp. TSA2s plasmid p2, complete sequence	205709-205729	0	1.0
NC_018078_10	10.9|2360911|21|NC_018078|CRT	2360911-2360931	21	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	60334-60354	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	16061-16081	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP053709	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence	278106-278126	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP006993	Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence	71625-71645	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	KR053194	Gordonia phage GAL1, complete genome	13539-13559	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP011809	Pandoraea faecigallinarum strain DSM 23572 plasmid pPF72-2, complete sequence	5131-5151	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP022727	Erwinia persicina strain B64 plasmid pEP2, complete sequence	87588-87608	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1495154-1495174	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_CP010865	Marinovum algicola DG 898 plasmid pMaD10, complete sequence	51349-51369	1	0.952
NC_018078_12	12.2|3984833|21|NC_018078|CRISPRCasFinder	3984833-3984853	21	NC_010608	Exiguobacterium arabatum pEspB plasmid	36860-36880	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NZ_KU254577	Pseudomonas aeruginosa strain HN39 plasmid pHN39-SIM, complete sequence	30285-30305	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	200082-200102	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NZ_AP015031	Pseudomonas putida strain KF715 plasmid pKF715B, complete sequence	50608-50628	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NZ_CP039644	Azospirillum sp. TSA2s plasmid p2, complete sequence	205709-205729	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	978022-978042	1	0.952
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	985548-985568	1	0.952
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	72145-72165	2	0.905
NC_018078_12	12.1|3984788|21|NC_018078|CRISPRCasFinder	3984788-3984808	21	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	466290-466310	2	0.905
NC_018078_12	12.3|3984878|21|NC_018078|CRISPRCasFinder	3984878-3984898	21	NZ_CP032828	Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence	695167-695187	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	55287-55307	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1345337-1345357	2	0.905
NC_018078_13	13.2|3985061|21|NC_018078|CRISPRCasFinder	3985061-3985081	21	MH153804	Rhodococcus phage Jace, complete genome	20827-20847	2	0.905
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4024254-4024277	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4460576-4460599	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP034768	Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence	122201-122224	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	37773-37796	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_AP019631	Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence	116652-116675	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_AP019631	Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence	72348-72371	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	KU716094	Mycobacterium phage Eidsmoe, complete genome	5649-5672	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MH371122	Mycobacterium phage Priya, complete genome	5650-5673	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MK016502	Mycobacterium phage Pat3, complete genome	22827-22850	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MK937593	Mycobacterium phage Flypotenuse, complete genome	23717-23740	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MG872835	Mycobacterium phage Conquerage, complete genome	5649-5672	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MH536820	Mycobacterium phage Glexan, complete genome	23717-23740	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	91001-91024	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP013426	Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence	44795-44818	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1701753-1701776	3	0.875
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MH271298	Microbacterium phage Floof, complete genome	37939-37962	3	0.875
NC_018078_10	10.8|2360869|24|NC_018078|CRT	2360869-2360892	24	NZ_CP014599	Yangia sp. CCB-MM3 plasmid unnamed3, complete sequence	110878-110901	3	0.875
NC_018078_10	10.8|2360869|24|NC_018078|CRT	2360869-2360892	24	NZ_CP028945	Vibrio sp. dhg plasmid unnamed1, complete sequence	122425-122448	3	0.875
NC_018078_3	3.1|369353|27|NC_018078|CRISPRCasFinder	369353-369379	27	NC_023591	Mycobacterium phage Adler, complete genome	61249-61275	4	0.852
NC_018078_3	3.1|369353|27|NC_018078|CRISPRCasFinder	369353-369379	27	KF981876	UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome	61247-61273	4	0.852
NC_018078_3	3.7|369749|27|NC_018078|CRISPRCasFinder	369749-369775	27	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	10066-10092	4	0.852
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	460464-460490	4	0.852
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NC_016652	Rhodococcus phage REQ2, complete genome	36035-36061	4	0.852
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	KY945355	Mycobacterium phage Shandong1, complete genome	25634-25660	4	0.852
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_CP015095	Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence	106725-106751	4	0.852
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NC_041888	Mycobacterium phage Tortellini, complete genome	37216-37242	4	0.852
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1096460-1096489	4	0.867
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1898211-1898234	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP025431	Paracoccus zhejiangensis strain J6 plasmid pPZ01, complete sequence	261506-261529	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	673134-673157	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP016822	Rhodococcus sp. p52 plasmid pDF03, complete sequence	60076-60099	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MN582086	Siphoviridae sp. ctdEk19, complete genome	33324-33347	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MF919502	Mycobacterium phage Demsculpinboyz, complete genome	21980-22003	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MT889380	Mycobacterium phage Coco12, complete genome	22623-22646	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NC_023698	Mycobacterium phage Avani, complete genome	21987-22010	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MT114167	Mycobacterium phage Phanphagia, complete genome	22278-22301	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	558871-558894	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1500559-1500582	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	295932-295955	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	1116335-1116358	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MN096355	Mycobacterium phage Purky, complete genome	48975-48998	4	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	MK279853	Gordonia phage Gray, complete genome	68404-68427	4	0.833
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_CP022566	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK02, complete sequence	524261-524287	4	0.852
NC_018078_3	3.1|369353|27|NC_018078|CRISPRCasFinder	369353-369379	27	LR794124	Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1	34861-34887	5	0.815
NC_018078_3	3.1|369353|27|NC_018078|CRISPRCasFinder	369353-369379	27	NC_012662	Vibrio phage VP93, complete genome	35301-35327	5	0.815
NC_018078_3	3.7|369749|27|NC_018078|CRISPRCasFinder	369749-369775	27	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	2189-2215	5	0.815
NC_018078_3	3.7|369749|27|NC_018078|CRISPRCasFinder	369749-369775	27	MN693945	Marine virus AFVG_250M952, complete genome	34909-34935	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	369429-369455	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	338832-338858	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	363377-363403	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP015368	Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence	104717-104743	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	338543-338569	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	340811-340837	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	342690-342716	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	343060-343086	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	355714-355740	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	343060-343086	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	348335-348361	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	343052-343078	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP020444	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence	69464-69490	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	363377-363403	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	355714-355740	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	342690-342716	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP044078	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence	10340-10366	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP031081	Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence	19365-19391	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MN586031	Gordonia phage Gambino, complete genome	3053-3079	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	KU998236	Gordonia phage Blueberry, complete genome	3053-3079	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MN062704	Gordonia phage JuJu, complete genome	3063-3089	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MK501729	Gordonia phage Walrus, complete genome	3053-3079	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NC_031226	Gordonia phage BaxterFox, complete genome	2982-3008	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MK967393	Rhodococcus phage Whack, complete genome	3063-3089	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MT723935	Gordonia phage Azula, complete genome	3053-3079	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	KU963249	Gordonia phage Yeezy, complete genome	2982-3008	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MH153808	Gordonia phage Petra, complete genome	3053-3079	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MT639650	Gordonia phage Ohgeesy, complete genome	2982-3008	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MH536818	Gordonia phage Frokostdame, complete genome	3055-3081	5	0.815
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	KX557275	Gordonia phage CarolAnn, complete genome	3052-3078	5	0.815
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	KX683875	Mycobacterium phage Baehexic, complete genome	12181-12207	5	0.815
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	KM197169	Mycobacterium phage Piro94, complete genome	12178-12204	5	0.815
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	MF668269	Mycobacterium phage Drake55, complete genome	12177-12203	5	0.815
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	MK284522	Mycobacterium phage Malec, complete genome	11950-11976	5	0.815
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	KM677210	Mycobacterium phage Larenn, complete genome	11945-11971	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_CP022264	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence	1800-1826	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_CP022264	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence	136919-136945	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	658056-658082	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1514868-1514894	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5852040-5852066	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_CP049908	Hymenobacter sp. HDW8 plasmid p_unnamed1, complete sequence	235006-235032	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_CP049700	Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence	263243-263269	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	MH576962	Streptomyces phage Satis, complete genome	95306-95332	5	0.815
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	MK620894	Streptomyces phage Kradal, complete genome	95310-95336	5	0.815
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1068923-1068952	5	0.833
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	1739900-1739929	5	0.833
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	233389-233418	5	0.833
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP031193	Humibacter sp. BT305 plasmid unnamed1	44938-44967	5	0.833
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP050092	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence	137673-137702	5	0.833
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	984252-984281	5	0.833
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1598936-1598965	5	0.833
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013631	Rhizobium sp. N324 plasmid pRspN324a, complete sequence	233398-233427	5	0.833
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP046705	Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence	292905-292934	5	0.833
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	AY950802	Haloarcula phage SH1, complete genome	16104-16133	5	0.833
NC_018078_6	6.16|927208|24|NC_018078|CRT	927208-927231	24	NC_006911	Streptomyces sp. F11 plasmid pFP11, complete sequence	11649-11672	5	0.792
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_CP048282	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248d, complete sequence	292199-292225	5	0.815
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_CP017563	Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence	273510-273536	5	0.815
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1214894-1214920	5	0.815
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	759448-759474	5	0.815
NC_018078_10	10.7|2360821|30|NC_018078|CRT	2360821-2360850	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1425504-1425533	5	0.833
NC_018078_10	10.7|2360821|30|NC_018078|CRT	2360821-2360850	30	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1378155-1378184	5	0.833
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NC_010850	Rhodococcus sp. NS1 plasmid pNSL1, complete sequence	92901-92931	5	0.839
NC_018078_3	3.1|369353|27|NC_018078|CRISPRCasFinder	369353-369379	27	NZ_CP045917	Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence	207335-207361	6	0.778
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	435770-435802	6	0.818
NC_018078_3	3.7|369749|27|NC_018078|CRISPRCasFinder	369749-369775	27	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	32942-32968	6	0.778
NC_018078_3	3.9|369899|27|NC_018078|CRISPRCasFinder	369899-369925	27	NC_009959	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence	50750-50776	6	0.778
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_CP009112	Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence	179708-179734	6	0.778
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	4846911-4846937	6	0.778
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	78863-78889	6	0.778
NC_018078_3	3.10|369959|27|NC_018078|CRISPRCasFinder	369959-369985	27	MK494099	Mycobacterium phage Typha, complete genome	33831-33857	6	0.778
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	GQ141189	Bifidobacterium phage Bbif-1, complete sequence	38062-38092	6	0.806
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	NZ_CP007796	Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence	658647-658673	6	0.778
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	NC_023606	Mycobacterium phage CRB1, complete genome	11649-11675	6	0.778
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	MK524491	Mycobacterium phage Whabigail7, complete genome	12139-12165	6	0.778
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	KX619650	Mycobacterium phage Jerm, complete genome	12089-12115	6	0.778
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	MN585998	Mycobacterium phage Bugsy, complete genome	12128-12154	6	0.778
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	JN408460	Mycobacterium phage Turbido, complete genome	12151-12177	6	0.778
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	MH077576	Mycobacterium phage AbbyPaige, complete genome	12129-12155	6	0.778
NC_018078_6	6.5|926713|27|NC_018078|CRT	926713-926739	27	MH825704	Mycobacterium phage LilTurb, complete genome	12148-12174	6	0.778
NC_018078_6	6.10|926923|27|NC_018078|CRT	926923-926949	27	NZ_AP021845	Azospira sp. I09 plasmid pAZI09, complete sequence	147990-148016	6	0.778
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	508-537	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	280809-280838	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	561652-561681	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP050083	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence	554428-554457	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP049733	Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence	542116-542145	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	610786-610815	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	571170-571199	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1563589-1563618	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	421135-421164	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1217050-1217079	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1265979-1266008	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1135414-1135443	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP037868	Hydrogenophaga pseudoflava strain DSM 1084 plasmid pDSM1084, complete sequence	5790-5819	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1195134-1195163	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1134511-1134540	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	762260-762289	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1168711-1168740	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1168700-1168729	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1135406-1135435	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1134762-1134791	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1135397-1135426	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1217165-1217194	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1217149-1217178	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1217142-1217171	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_019408	Caulobacter phage CcrRogue, complete genome	180466-180495	6	0.8
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	174181-174210	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP017941	Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence	270228-270257	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	MK937608	Microbacterium phage Cressida, complete genome	54022-54051	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP050083	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence	554437-554466	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP049733	Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence	542125-542154	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP017592	Pantoea stewartii subsp. stewartii DC283 plasmid ppDSJ01, complete sequence	7337-7366	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP008898	Enterobacter hormaechei subsp. hoffmannii ECNIH3 plasmid pENT-576, complete sequence	43955-43984	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP023489	Klebsiella pneumoniae subsp. pneumoniae strain ST101:960186733 plasmid p19-10_02, complete sequence	73653-73682	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP043515	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed4, complete sequence	36331-36360	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	571179-571208	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_LT984809	Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence	317155-317184	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP026371	Klebsiella quasipneumoniae strain A708 plasmid pA708-3, complete sequence	116386-116415	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP050069	Klebsiella aerogenes strain 035 plasmid p035_A-VIM-1, complete sequence	79588-79617	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP039425	Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence	132572-132601	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP009856	UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-784, complete sequence	26128-26157	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP039430	Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence	132570-132599	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP040937	Hymenobacter sp. DG01 plasmid unnamed, complete sequence	32030-32059	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	14031-14060	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	17715-17744	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP006588	Hymenobacter sp. APR13 plasmid pHA, complete sequence	19031-19060	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1930897-1930926	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	190353-190382	6	0.8
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	MH029534	Myoviridae environmental samples clone NHS-Seq2, complete sequence	34123-34152	6	0.8
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	MT723940	Mycobacterium phage Ellie, complete genome	24126-24161	6	0.833
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_AP022566	Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence	1478-1504	6	0.778
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	94030-94056	6	0.778
NC_018078_10	10.7|2360821|30|NC_018078|CRT	2360821-2360850	30	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	262130-262159	6	0.8
NC_018078_10	10.7|2360821|30|NC_018078|CRT	2360821-2360850	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1624787-1624816	6	0.8
NC_018078_10	10.7|2360821|30|NC_018078|CRT	2360821-2360850	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1624922-1624951	6	0.8
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NC_009478	Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence	8328-8358	6	0.806
NC_018078_3	3.4|369548|27|NC_018078|CRISPRCasFinder	369548-369574	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	48081-48107	7	0.741
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MK977708	Mycobacterium phage Fulbright, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MG099948	Mycobacterium phage Philonius, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MH926055	Mycobacterium phage Chewbacca, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MT723932	Mycobacterium phage Schnauzer, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	KU935726	Mycobacterium phage Xerxes, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	KU935730	Mycobacterium phage Pipsqueaks, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MH316570	Mycobacterium phage Silvafighter, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MK524518	Mycobacterium phage Smurph, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MK524515	Mycobacterium phage Parmesanjohn, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MH697585	Mycobacterium phage Gex, complete genome	10280-10310	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	KM588359	Mycobacterium phage Carcharodon, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MH697576	Mycobacterium phage Aggie, complete genome	10282-10312	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MH697593	Mycobacterium phage Tapioca, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	MG099936	Mycobacterium phage Andies, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	NC_031243	Mycobacterium phage Xeno, complete genome	10281-10311	7	0.774
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	JN256079	Mycobacterium phage Charlie, complete genome	10281-10311	7	0.774
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	943873-943902	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	392100-392129	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1838430-1838459	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	616186-616215	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	397449-397478	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1703655-1703684	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	212329-212358	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	679499-679528	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1744018-1744047	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1760732-1760761	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	178925-178954	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	75369-75398	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	153012-153041	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	589998-590027	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	81538-81567	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	845884-845913	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	258296-258325	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1723933-1723962	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1859622-1859651	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1841724-1841753	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1841724-1841753	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	137321-137350	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	258496-258525	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	257917-257946	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	234345-234374	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	461507-461536	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	254201-254230	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	236985-237014	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	298368-298397	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	258487-258516	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	461579-461608	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	390422-390451	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1964821-1964850	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	461516-461545	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	237930-237959	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	849014-849043	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1227007-1227036	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	238244-238273	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	245279-245308	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	235437-235466	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	126762-126791	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	234570-234599	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	258309-258338	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	231309-231338	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	235690-235719	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	238261-238290	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	252665-252694	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	236955-236984	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	251052-251081	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	298440-298469	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	230351-230380	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	252665-252694	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	236955-236984	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	461938-461967	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	252665-252694	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	438995-439024	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	230352-230381	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	252665-252694	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	236955-236984	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	236955-236984	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	236955-236984	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	230352-230381	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	245262-245291	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	245236-245265	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	241864-241893	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	240004-240033	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	235466-235495	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	230352-230381	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	252665-252694	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	280525-280554	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	251050-251079	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	230352-230381	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	230352-230381	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	236955-236984	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	251053-251082	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	HM560026	Uncultured bacterium plasmid pTRACA45, complete sequence	1764-1793	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_010867	Neisseria lactamica plasmid pNL3.1, complete sequence	3216-3245	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	121720-121749	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	535160-535189	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	326858-326887	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	121664-121693	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	KT997827	Uncultured Mediterranean phage uvDeep-CGR0-KM15-C219, complete genome	28429-28458	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	AP021850	Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome	235977-236006	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1424992-1425021	7	0.767
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	KT997829	Uncultured Mediterranean phage uvDeep-CGR0-KM22-C158, complete genome	24686-24715	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013634	Rhizobium sp. N324 plasmid pRspN324d, complete sequence	278785-278814	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP035001	Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence	113824-113853	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP040820	Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence	158849-158878	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	384914-384943	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	317121-317150	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP020909	Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence	385410-385439	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	260932-260961	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP020951	Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence	329309-329338	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NC_021908	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence	391416-391445	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP020441	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence	243975-244004	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	301676-301705	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP044080	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence	201076-201105	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	635292-635321	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	422833-422862	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	494408-494437	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	MN582086	Siphoviridae sp. ctdEk19, complete genome	33318-33347	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	864583-864612	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP022700	Acetobacter tropicalis strain BDGP1 plasmid pAtBDGP1A, complete sequence	61493-61522	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1238691-1238720	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	1484042-1484071	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	1466967-1466996	7	0.767
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP031082	Paracoccus yeei strain CCUG 32053 plasmid pYEE4, complete sequence	119508-119537	7	0.767
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	NC_022087	Mycobacterium phage AnnaL29, complete genome	5558-5593	7	0.806
NC_018078_10	10.6|2360776|27|NC_018078|CRT	2360776-2360802	27	NZ_CP015006	Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence	22155-22181	7	0.741
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	147567-147597	7	0.774
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	36995-37025	7	0.774
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP042263	Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence	372247-372277	7	0.774
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1386736-1386768	8	0.758
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	35126-35158	8	0.758
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1241611-1241643	8	0.758
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	275839-275871	8	0.758
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	310597-310629	8	0.758
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2714450-2714479	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	837910-837939	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	424702-424731	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	975216-975245	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1013021-1013050	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_KY126370	Enterobacter cloacae subsp. cloacae strain MN201516 plasmid pOP-I, complete sequence	93253-93282	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP054625	Cupriavidus gilardii strain FDAARGOS_639 plasmid unnamed1, complete sequence	22400-22429	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1889334-1889363	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_LT960615	Hartmannibacter diazotrophicus strain E19T plasmid HDIAp1, complete sequence	21202-21231	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP046347	Citrobacter portucalensis strain FDAARGOS_738 plasmid unnamed1, complete sequence	30108-30137	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP044100	Citrobacter werkmanii strain FDAARGOS_616 plasmid unnamed1, complete sequence	32856-32885	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP032156	Mycobacterium sp. ELW1 plasmid pELW1-1, complete sequence	111116-111145	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	KY555144	Caulobacter phage Ccr5, complete genome	178242-178271	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_KP873172	Pseudomonas aeruginosa PAO1 plasmid pAMBL1, complete sequence	21059-21088	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP045203	Citrobacter sp. NMI7904_11 plasmid pCTEL-2, complete sequence	159096-159125	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NC_021492	Enterobacter sp. R4-368 plasmid pENT01, complete sequence	50097-50126	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP022156	Escherichia coli strain ABWA45 plasmid pABWA45_2, complete sequence	15249-15278	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP024682	Citrobacter freundii strain UMH14 plasmid pUMH14_2, complete sequence	41943-41972	8	0.733
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	242723-242752	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	28649-28678	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	310870-310899	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	462801-462830	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	292109-292138	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	287383-287412	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	292305-292334	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	292675-292704	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	306458-306487	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	292675-292704	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	295900-295929	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	292670-292699	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	306458-306487	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	292305-292334	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	298287-298316	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1682210-1682239	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	294530-294559	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_LR134452	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence	375826-375855	8	0.733
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	112972-113001	8	0.733
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	MG770216	Mycobacterium phage Rem711, complete genome	26292-26327	8	0.778
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	KY087993	Mycobacterium phage Hammy, complete genome	24359-24394	8	0.778
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	MF140406	Mycobacterium phage DarthP, complete genome	24368-24403	8	0.778
NC_018078_7	7.16|1291513|29|NC_018078|PILER-CR	1291513-1291541	29	MK599315	Pseudomonas phage PA1C, complete genome	299172-299200	8	0.724
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	CP033373	Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence	12237-12267	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1260343-1260373	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1009358-1009388	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1260501-1260531	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1009351-1009381	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	756669-756699	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1137767-1137797	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1009365-1009395	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1260057-1260087	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1260001-1260031	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	981946-981976	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	938267-938297	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	748414-748444	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	896022-896052	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NZ_CP027299	Streptomyces sp. SGAir0924 plasmid unnamed_5	215713-215743	8	0.742
NC_018078_11	11.7|3738069|31|NC_018078|CRT	3738069-3738099	31	NC_014213	Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence	111748-111778	8	0.742
NC_018078_13	13.5|3985226|36|NC_018078|CRISPRCasFinder	3985226-3985261	36	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	826111-826146	8	0.778
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	91175-91207	9	0.727
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP016287	Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence	668963-668995	9	0.727
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	789706-789738	9	0.727
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	625853-625885	9	0.727
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	NZ_CP014964	Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence	13698-13728	9	0.71
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	NC_015974	Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence	20960-20990	9	0.71
NC_018078_4	4.1|692359|31|NC_018078|CRISPRCasFinder	692359-692389	31	NZ_CP005085	Sphingobium sp. TKS plasmid pTK1, complete sequence	15390-15420	9	0.71
NC_018078_6	6.13|927064|30|NC_018078|CRT	927064-927093	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5046041-5046070	9	0.7
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NC_005241	Cupriavidus necator H16 megaplasmid pHG1, complete sequence	65937-65966	9	0.7
NC_018078_6	6.15|927160|30|NC_018078|CRT	927160-927189	30	NZ_CP039289	Cupriavidus necator H16 plasmid pHG1, complete sequence	65937-65966	9	0.7
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	MF140398	Mycobacterium phage Amohnition, complete genome	24446-24481	9	0.75
NC_018078_10	10.7|2360821|30|NC_018078|CRT	2360821-2360850	30	NZ_CP022197	Celeribacter ethanolicus strain TSPH2 plasmid unnamed, complete sequence	25141-25170	9	0.7
NC_018078_11	11.5|3737928|34|NC_018078|CRT	3737928-3737961	34	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	922290-922323	9	0.735
NC_018078_11	11.5|3737928|34|NC_018078|CRT	3737928-3737961	34	MG812496	Gordonia phage SallySpecial, complete genome	7675-7708	9	0.735
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	91179-91211	10	0.697
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	90245-90277	10	0.697
NC_018078_3	3.6|369683|33|NC_018078|CRISPRCasFinder	369683-369715	33	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	99166-99198	10	0.697
NC_018078_6	6.2|926560|39|NC_018078|CRT	926560-926598	39	NZ_CP044080	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence	107058-107096	10	0.744
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	MN369764	Mycobacterium phage Rahalelujah, complete genome	24340-24375	10	0.722
NC_018078_6	6.17|927250|36|NC_018078|CRT	927250-927285	36	NZ_CP025548	Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence	25147-25182	10	0.722
NC_018078_7	7.4|1290631|34|NC_018078|PILER-CR,CRISPRCasFinder,CRT	1290631-1290664	34	NZ_AP022335	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence	171698-171731	10	0.706
NC_018078_8	8.10|1293996|35|NC_018078|CRT,PILER-CR,CRISPRCasFinder	1293996-1294030	35	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	414652-414686	10	0.714
NC_018078_11	11.5|3737928|34|NC_018078|CRT	3737928-3737961	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	470079-470112	10	0.706
NC_018078_11	11.5|3737928|34|NC_018078|CRT	3737928-3737961	34	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	68774-68807	10	0.706
NC_018078_11	11.5|3737928|34|NC_018078|CRT	3737928-3737961	34	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NC_018078_11	11.5|3737928|34|NC_018078|CRT	3737928-3737961	34	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	172270-172303	10	0.706
NC_018078_11	11.9|3738201|37|NC_018078|CRT	3738201-3738237	37	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	975062-975098	10	0.73
NC_018078_11	11.5|3737928|34|NC_018078|CRT	3737928-3737961	34	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	326578-326611	11	0.676

1. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacaccggcagcggc	Protospacer
*********************

2. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP039644 (Azospirillum sp. TSA2s plasmid p2, complete sequence) position: , mismatch: 0, identity: 1.0

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacaccggcagcggc	Protospacer
*********************

3. spacer 10.9|2360911|21|NC_018078|CRT matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 1, identity: 0.952

aatggcgggctcctgttcggc	CRISPR spacer
aatggcgggctcctgctcggc	Protospacer
***************.*****

4. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaagaccggcagcggc	Protospacer
******** ************

5. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP053709 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacaccggccgcggc	Protospacer
*************** *****

6. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP006993 (Methylobacterium sp. AMS5 plasmid pAMS5a, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
gtcggcaacaccggcagcggc	Protospacer
* *******************

7. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to KR053194 (Gordonia phage GAL1, complete genome) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacaccggcagcagc	Protospacer
******************.**

8. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP011809 (Pandoraea faecigallinarum strain DSM 23572 plasmid pPF72-2, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacgccggcagcggc	Protospacer
*********.***********

9. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP022727 (Erwinia persicina strain B64 plasmid pEP2, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacaccgtcagcggc	Protospacer
************* *******

10. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacacctgcagcggc	Protospacer
************ ********

11. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_CP010865 (Marinovum algicola DG 898 plasmid pMaD10, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcagcggc	CRISPR spacer
ggcggcaacaccggcggcggc	Protospacer
***************.*****

12. spacer 12.2|3984833|21|NC_018078|CRISPRCasFinder matches to NC_010608 (Exiguobacterium arabatum pEspB plasmid) position: , mismatch: 1, identity: 0.952

agctccaacttcggcggcggc	CRISPR spacer
agctacaacttcggcggcggc	Protospacer
**** ****************

13. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NZ_KU254577 (Pseudomonas aeruginosa strain HN39 plasmid pHN39-SIM, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggccgcaacaccggcaacggc	Protospacer
*** *****************

14. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacaccggcagcggc	Protospacer
****************.****

15. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NZ_AP015031 (Pseudomonas putida strain KF715 plasmid pKF715B, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggccgcaacaccggcaacggc	Protospacer
*** *****************

16. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NZ_CP039644 (Azospirillum sp. TSA2s plasmid p2, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacaccggcagcggc	Protospacer
****************.****

17. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacaccggcaatggc	Protospacer
*****************.***

18. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 1, identity: 0.952

ggcggcaacaccggcaacggc	CRISPR spacer
ggcggcaacagcggcaacggc	Protospacer
********** **********

19. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
ttcggcaacaccggcagcggc	Protospacer
  *******************

20. spacer 12.1|3984788|21|NC_018078|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 2, identity: 0.905

ggcggcaacaccggcagcggc	CRISPR spacer
cacggcaacaccggcagcggc	Protospacer
 .*******************

21. spacer 12.3|3984878|21|NC_018078|CRISPRCasFinder matches to NZ_CP032828 (Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.905

agcggcaaccgaggcagcgac	CRISPR spacer
ggcggcaaccgaggcagcgag	Protospacer
.******************* 

22. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
atcggcaacaccggcaacggc	Protospacer
. *******************

23. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
atcggcaacaccggcaacggc	Protospacer
. *******************

24. spacer 13.2|3985061|21|NC_018078|CRISPRCasFinder matches to MH153804 (Rhodococcus phage Jace, complete genome) position: , mismatch: 2, identity: 0.905

ggcggcaacaccggcaacggc	CRISPR spacer
ctcggcaacaccggcaacggc	Protospacer
  *******************

25. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgacctcggcggcgcgggcga	Protospacer
.***************** ****.

26. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
caccggcctgggcggcgctggcgg	Protospacer
 ****.*** **************

27. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP034768 (Enterobacter sp. N18-03635 plasmid pFRI-6, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
taacgtcctcggcggcgctggcgg	Protospacer
 * ** ******************

28. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
agccgacctcggcggcgatggcgc	Protospacer
*.*************** ***** 

29. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_AP019631 (Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
taacgtcctcggcggcgctggcgg	Protospacer
 * ** ******************

30. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_AP019631 (Enterobacter asburiae strain 17Nkhm-UP2 plasmid pEAS17Nkhm-UP2-1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
taacgtcctcggcggcgctggcgg	Protospacer
 * ** ******************

31. spacer 6.16|927208|24|NC_018078|CRT matches to KU716094 (Mycobacterium phage Eidsmoe, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgcgctcggcggcgctggcgg	Protospacer
.****  *****************

32. spacer 6.16|927208|24|NC_018078|CRT matches to MH371122 (Mycobacterium phage Priya, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgcgctcggcggcgctggcgg	Protospacer
.****  *****************

33. spacer 6.16|927208|24|NC_018078|CRT matches to MK016502 (Mycobacterium phage Pat3, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
catcggcctcggcggcgctggcgg	Protospacer
 *.**.******************

34. spacer 6.16|927208|24|NC_018078|CRT matches to MK937593 (Mycobacterium phage Flypotenuse, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
catcggcctcggcggcgctggcgg	Protospacer
 *.**.******************

35. spacer 6.16|927208|24|NC_018078|CRT matches to MG872835 (Mycobacterium phage Conquerage, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
gaccgcgctcggcggcgctggcgg	Protospacer
.****  *****************

36. spacer 6.16|927208|24|NC_018078|CRT matches to MH536820 (Mycobacterium phage Glexan, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
catcggcctcggcggcgctggcgg	Protospacer
 *.**.******************

37. spacer 6.16|927208|24|NC_018078|CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
aaccggcctcggcggcgctgccgc	Protospacer
*****.************** ** 

38. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP013426 (Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
caccgagctcggcggcgctgccgg	Protospacer
 ***** ************* ***

39. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
caccggcctcggcggcgcgggcgg	Protospacer
 ****.************ *****

40. spacer 6.16|927208|24|NC_018078|CRT matches to MH271298 (Microbacterium phage Floof, complete genome) position: , mismatch: 3, identity: 0.875

aaccgacctcggcggcgctggcgg	CRISPR spacer
aacccacctcggcggcgatggcgc	Protospacer
**** ************ ***** 

41. spacer 10.8|2360869|24|NC_018078|CRT matches to NZ_CP014599 (Yangia sp. CCB-MM3 plasmid unnamed3, complete sequence) position: , mismatch: 3, identity: 0.875

accggcactaatgtcaccggcggt	CRISPR spacer
aacggcactaatgtcaccggcgtg	Protospacer
* ********************  

42. spacer 10.8|2360869|24|NC_018078|CRT matches to NZ_CP028945 (Vibrio sp. dhg plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.875

accggcactaatgtcaccggcggt	CRISPR spacer
accggcactaatgtcaccgccaga	Protospacer
******************* *.* 

43. spacer 3.1|369353|27|NC_018078|CRISPRCasFinder matches to NC_023591 (Mycobacterium phage Adler, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

44. spacer 3.1|369353|27|NC_018078|CRISPRCasFinder matches to KF981876 (UNVERIFIED: Mycobacterium phage ADLER F1725, complete genome) position: , mismatch: 4, identity: 0.852

-aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
cagtgc-ccggtgtccccatcgcccgtg	Protospacer
 *..** ********* ***********

45. spacer 3.7|369749|27|NC_018078|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 4, identity: 0.852

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ccgaagccgatgtcgtagcggccggcg	Protospacer
 ************.***** *****.*

46. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgaaggtgaggtcgccgggg	Protospacer
.* ********* ***********.**

47. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NC_016652 (Rhodococcus phage REQ2, complete genome) position: , mismatch: 4, identity: 0.852

accccgccgaagttgaggtcgccgagg	CRISPR spacer
acggcgccgaagttgaggccgccgacg	Protospacer
**  **************.****** *

48. spacer 6.10|926923|27|NC_018078|CRT matches to KY945355 (Mycobacterium phage Shandong1, complete genome) position: , mismatch: 4, identity: 0.852

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgcatccggcggcggcggttgcgttct	Protospacer
** **************** ***** .

49. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_CP015095 (Pelagibaca abyssi strain JLT2014 plasmid pPABY4, complete sequence) position: , mismatch: 4, identity: 0.852

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cggcctcggcggcggcggtggcgttgc	Protospacer
*** ..*************.*******

50. spacer 6.10|926923|27|NC_018078|CRT matches to NC_041888 (Mycobacterium phage Tortellini, complete genome) position: , mismatch: 4, identity: 0.852

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cggccgcggcggcggcggtagcggtgc	Protospacer
*** . ***************** ***

51. spacer 6.15|927160|30|NC_018078|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 4, identity: 0.867

cctgctgttcggctccggcggcgctggcgg-	CRISPR spacer
gctgctgttcggcgccggcggcg-tggtggc	Protospacer
 ************ ********* ***.** 

52. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ctacgaccacggcggcgctggcgg	Protospacer
   ***** ***************

53. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP025431 (Paracoccus zhejiangensis strain J6 plasmid pPZ01, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
gcccgatctcggcggcgctggcgt	Protospacer
. ****.**************** 

54. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tcccgacctcggcggtgctggcgc	Protospacer
  *************.******* 

55. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP016822 (Rhodococcus sp. p52 plasmid pDF03, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
cgtcgacgtcggcggcgctggcgg	Protospacer
 ..**** ****************

56. spacer 6.16|927208|24|NC_018078|CRT matches to MN582086 (Siphoviridae sp. ctdEk19, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
cttcgacttcggcggcgctggcgg	Protospacer
  .****.****************

57. spacer 6.16|927208|24|NC_018078|CRT matches to MF919502 (Mycobacterium phage Demsculpinboyz, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

58. spacer 6.16|927208|24|NC_018078|CRT matches to MT889380 (Mycobacterium phage Coco12, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

59. spacer 6.16|927208|24|NC_018078|CRT matches to NC_023698 (Mycobacterium phage Avani, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

60. spacer 6.16|927208|24|NC_018078|CRT matches to MT114167 (Mycobacterium phage Phanphagia, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ccgcggcctcggcggcgctggcgg	Protospacer
   **.******************

61. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
cgccgacctcggcggcggtggcga	Protospacer
 .*************** *****.

62. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tcccgacctcggcggtgctggcgc	Protospacer
  *************.******* 

63. spacer 6.16|927208|24|NC_018078|CRT matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ctacgaccacggcggcgctggcgg	Protospacer
   ***** ***************

64. spacer 6.16|927208|24|NC_018078|CRT matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tctcgacctcggcggcgatggcgg	Protospacer
  .************** ******

65. spacer 6.16|927208|24|NC_018078|CRT matches to MN096355 (Mycobacterium phage Purky, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
tgccgacctcggctgcgctggcgc	Protospacer
 .*********** ********* 

66. spacer 6.16|927208|24|NC_018078|CRT matches to MK279853 (Gordonia phage Gray, complete genome) position: , mismatch: 4, identity: 0.833

aaccgacctcggcggcgctggcgg	CRISPR spacer
ggtcgacctcgacggcgctggcgg	Protospacer
...********.************

67. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_CP022566 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK02, complete sequence) position: , mismatch: 4, identity: 0.852

gtcggcggactcgcggctgacgccggt	CRISPR spacer
ggcggcggactcgcggctgtcgccatt	Protospacer
* ***************** ****. *

68. spacer 3.1|369353|27|NC_018078|CRISPRCasFinder matches to LR794124 (Vibrio phage vB_Vc_SrVc9 genome assembly, chromosome: 1) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .* 

69. spacer 3.1|369353|27|NC_018078|CRISPRCasFinder matches to NC_012662 (Vibrio phage VP93, complete genome) position: , mismatch: 5, identity: 0.815

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
aacgcaccgttgtccacatcaccaatc	Protospacer
********* **********.** .* 

70. spacer 3.7|369749|27|NC_018078|CRISPRCasFinder matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
gcgaagccgaagttgtagctgcgctcg	Protospacer
********** ***********   .*

71. spacer 3.7|369749|27|NC_018078|CRISPRCasFinder matches to MN693945 (Marine virus AFVG_250M952, complete genome) position: , mismatch: 5, identity: 0.815

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
atgaagccgatgttgtcgctaccgggg	Protospacer
..************** ***.**** *

72. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

73. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

74. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

75. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP015368 (Methylobacterium phyllosphaerae strain CBMB27 plasmid CBMB27-p1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccccgcggaagttgaggtcgcgggtg	Protospacer
 ****** ************** *. *

76. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

77. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

78. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

79. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

80. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

81. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

82. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

83. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

84. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP020444 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

85. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

86. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

87. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
gcgccgccgatgttgagggcgccgagt	Protospacer
.* ******* ******* ******* 

88. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP044078 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

89. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP031081 (Paracoccus yeei strain CCUG 32053 plasmid pYEE3, complete sequence) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcaccgccgaagttgaagtggccgagc	Protospacer
 * *************.** ****** 

90. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MN586031 (Gordonia phage Gambino, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

91. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to KU998236 (Gordonia phage Blueberry, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

92. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MN062704 (Gordonia phage JuJu, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

93. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MK501729 (Gordonia phage Walrus, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

94. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NC_031226 (Gordonia phage BaxterFox, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

95. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MK967393 (Rhodococcus phage Whack, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tccttaccgaagttgaggtcgacgagg	Protospacer
 **...*************** *****

96. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MT723935 (Gordonia phage Azula, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

97. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to KU963249 (Gordonia phage Yeezy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

98. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MH153808 (Gordonia phage Petra, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

99. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MT639650 (Gordonia phage Ohgeesy, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

100. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MH536818 (Gordonia phage Frokostdame, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

101. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to KX557275 (Gordonia phage CarolAnn, complete genome) position: , mismatch: 5, identity: 0.815

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tcgacgccgaagttgatgtcgacgagg	Protospacer
 *  ************ **** *****

102. spacer 6.5|926713|27|NC_018078|CRT matches to KX683875 (Mycobacterium phage Baehexic, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

103. spacer 6.5|926713|27|NC_018078|CRT matches to KM197169 (Mycobacterium phage Piro94, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

104. spacer 6.5|926713|27|NC_018078|CRT matches to MF668269 (Mycobacterium phage Drake55, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

105. spacer 6.5|926713|27|NC_018078|CRT matches to MK284522 (Mycobacterium phage Malec, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

106. spacer 6.5|926713|27|NC_018078|CRT matches to KM677210 (Mycobacterium phage Larenn, complete genome) position: , mismatch: 5, identity: 0.815

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttgccggtgggctgttcagcggcgg	Protospacer
    ****************.******

107. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_CP022264 (Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
ggcaggcggcggcggcggtagcgttgg	Protospacer
 * *  ******************** 

108. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_CP022264 (Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
ggcaggcggcggcggcggtagcgttgg	Protospacer
 * *  ******************** 

109. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
aggatccggccgcggcggtagcgctcg	Protospacer
 ********* ************.*  

110. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
aggatccggccgcggcggtagcgctcg	Protospacer
 ********* ************.*  

111. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgggtccggcggcggcggtggcggttt	Protospacer
***.***************.*** * .

112. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_CP049908 (Hymenobacter sp. HDW8 plasmid p_unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgactccggcggcgggggtagcgttcg	Protospacer
**. *********** *********  

113. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_CP049700 (Bradyrhizobium sp. 1S5 strain 323S2 plasmid pB323S2a, complete sequence) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cgccgccggcggcggcggtggcgttgg	Protospacer
**   **************.****** 

114. spacer 6.10|926923|27|NC_018078|CRT matches to MH576962 (Streptomyces phage Satis, complete genome) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
tgactccggcggcggccgtggcgttgc	Protospacer
.*. ************ **.*******

115. spacer 6.10|926923|27|NC_018078|CRT matches to MK620894 (Streptomyces phage Kradal, complete genome) position: , mismatch: 5, identity: 0.815

cggatccggcggcggcggtagcgttgc	CRISPR spacer
tgactccggcggcggccgtggcgttgc	Protospacer
.*. ************ **.*******

116. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgaggccggcctgctggtcgtctccgggct	Protospacer
*** **************** ******   

117. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
agattccggcctgttcgtcggctccggcgg	Protospacer
 **. ********.* **************

118. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgccatcggcctgctgctcggcaccggcgg	Protospacer
** *..********** ***** *******

119. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP031193 (Humibacter sp. BT305 plasmid unnamed1) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgccgccggcctgctggtcggcgcggcggg	Protospacer
** ******************* * *  **

120. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP050092 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence) position: , mismatch: 5, identity: 0.833

cgacgccggcctgctggtcggc-tccggcgg	CRISPR spacer
cgacgccggcatgccggtcggcttcctgct-	Protospacer
********** ***.******* *** **  

121. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
attgctgttcggctgcggcggcgcgggcgc	Protospacer
 .************ ********* **** 

122. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
attgctgttcggctgcggcggcgcgggcgc	Protospacer
 .************ ********* **** 

123. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013631 (Rhizobium sp. N324 plasmid pRspN324a, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcactcgg	Protospacer
*******.***** **********   ***

124. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP046705 (Nostoc sp. ATCC 53789 plasmid pNsp_b, complete sequence) position: , mismatch: 5, identity: 0.833

cctgctg--ttcggctccggcggcgctggcgg	CRISPR spacer
--tactgattacggctccggcggtgctggcgg	Protospacer
  *.***  * ************.********

125. spacer 6.15|927160|30|NC_018078|CRT matches to AY950802 (Haloarcula phage SH1, complete genome) position: , mismatch: 5, identity: 0.833

--cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ggcctac--ttcggctccggcggctccggcgg	Protospacer
  ***.*  *************** *.*****

126. spacer 6.16|927208|24|NC_018078|CRT matches to NC_006911 (Streptomyces sp. F11 plasmid pFP11, complete sequence) position: , mismatch: 5, identity: 0.792

aaccgacctcggcggcgctggcgg	CRISPR spacer
gggcgacctcggcggcgctggcct	Protospacer
.. *******************  

127. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_CP048282 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248d, complete sequence) position: , mismatch: 5, identity: 0.815

gtcggcggactcgcggctgacgccggt	CRISPR spacer
ggcggcggactcgcggctgtcgccatc	Protospacer
* ***************** ****. .

128. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_CP017563 (Paraburkholderia sprentiae WSM5005 plasmid pl1WSM5005, complete sequence) position: , mismatch: 5, identity: 0.815

gtcggcggactcgcggctgacgccggt	CRISPR spacer
gtcggcggcctcgcggctgatgccata	Protospacer
******** ***********.***.  

129. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 5, identity: 0.815

gtcggcggactcgcggctgacgccggt	CRISPR spacer
ctcggcgcactcgaggctgacgcctgc	Protospacer
 ****** ***** ********** *.

130. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 5, identity: 0.815

gtcggcggactcgcggctgacgccggt	CRISPR spacer
ggcggcggtttcgcggctgacgccgtc	Protospacer
* ****** .*************** .

131. spacer 10.7|2360821|30|NC_018078|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 5, identity: 0.833

gacggcgggttgttcttcggcgtgggcggt	CRISPR spacer
gccggcgggttgttctgcggcgttggcgca	Protospacer
* ************** ****** ****  

132. spacer 10.7|2360821|30|NC_018078|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

gacggcgggttgttcttcggcgtgggcggt	CRISPR spacer
gccggcgggttgttctgcggcgttggcgca	Protospacer
* ************** ****** ****  

133. spacer 11.7|3738069|31|NC_018078|CRT matches to NC_010850 (Rhodococcus sp. NS1 plasmid pNSL1, complete sequence) position: , mismatch: 5, identity: 0.839

aacgccc-acttcaccgccgttgccgccgtca	CRISPR spacer
-acacccgacttcaccgccgctgccgccgaga	Protospacer
 **.*** ************.********  *

134. spacer 3.1|369353|27|NC_018078|CRISPRCasFinder matches to NZ_CP045917 (Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence) position: , mismatch: 6, identity: 0.778

aacgcaccggtgtccacatcgcccgtg	CRISPR spacer
agttcactggtgtccacatcgcccgaa	Protospacer
*.. ***.***************** .

135. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.818

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agcaggtcgatcacgatctggccgttgccggcg	Protospacer
**   *.***** ******************.*

136. spacer 3.7|369749|27|NC_018078|CRISPRCasFinder matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 6, identity: 0.778

gcgaagccgatgttgtagctgccggtg	CRISPR spacer
ggataggcgatgttgtagctgccggaa	Protospacer
* . ** ****************** .

137. spacer 3.9|369899|27|NC_018078|CRISPRCasFinder matches to NC_009959 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI05, complete sequence) position: , mismatch: 6, identity: 0.778

gccaagccgatatcgaagatcccggtg	CRISPR spacer
accatgccgatatcgacgatcccgtcc	Protospacer
.*** *********** ******* . 

138. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_CP009112 (Rhodococcus opacus strain 1CP plasmid pR1CP1, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
tagacgccgaagtcgaggtcggcgagg	Protospacer
    *********.******* *****

139. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
ctcccgccgaagttgagggtgccgaac	Protospacer
 .**************** .*****. 

140. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
aagaagccgaagttgaggtcgccgtag	Protospacer
*    ******************* .*

141. spacer 3.10|369959|27|NC_018078|CRISPRCasFinder matches to MK494099 (Mycobacterium phage Typha, complete genome) position: , mismatch: 6, identity: 0.778

accccgccgaagttgaggtcgccgagg	CRISPR spacer
cggtcgccgaggtcgaggtcgccgagg	Protospacer
   .******.**.*************

142. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to GQ141189 (Bifidobacterium phage Bbif-1, complete sequence) position: , mismatch: 6, identity: 0.806

agcgcgaacggcaagccgaac----cgttggaccc	CRISPR spacer
agcgcgaacggccagccgaaccatgcgctgg----	Protospacer
************ ********    **.***    

143. spacer 6.5|926713|27|NC_018078|CRT matches to NZ_CP007796 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p3, complete sequence) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
gatggccggtaggctgttgaacggcgc	Protospacer
.. *******.******* ******* 

144. spacer 6.5|926713|27|NC_018078|CRT matches to NC_023606 (Mycobacterium phage CRB1, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

145. spacer 6.5|926713|27|NC_018078|CRT matches to MK524491 (Mycobacterium phage Whabigail7, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

146. spacer 6.5|926713|27|NC_018078|CRT matches to KX619650 (Mycobacterium phage Jerm, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

147. spacer 6.5|926713|27|NC_018078|CRT matches to MN585998 (Mycobacterium phage Bugsy, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

148. spacer 6.5|926713|27|NC_018078|CRT matches to JN408460 (Mycobacterium phage Turbido, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

149. spacer 6.5|926713|27|NC_018078|CRT matches to MH077576 (Mycobacterium phage AbbyPaige, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

150. spacer 6.5|926713|27|NC_018078|CRT matches to MH825704 (Mycobacterium phage LilTurb, complete genome) position: , mismatch: 6, identity: 0.778

aggggccggtgggctgttcaacggcgg	CRISPR spacer
ccttggcggtgggctgttcagcggcgg	Protospacer
    * **************.******

151. spacer 6.10|926923|27|NC_018078|CRT matches to NZ_AP021845 (Azospira sp. I09 plasmid pAZI09, complete sequence) position: , mismatch: 6, identity: 0.778

cggatccggcggcggcggtagcgttgc	CRISPR spacer
cggatcctgcggcggcggtagaaagcc	Protospacer
******* ************* .   *

152. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gagcgtcggcctgctggtcggcttcggcgc	Protospacer
 ..**.*****************.***** 

153. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gagcgtcggcctgctggtcggcttcggcgc	Protospacer
 ..**.*****************.***** 

154. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgacggcctggtggtcggctacctcga	Protospacer
***** ******* ********* *  **.

155. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP050083 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgatcggcctgctgctcggcaccggcgg	Protospacer
**  ..********** ***** *******

156. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP049733 (Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgatcggcctgctgctcggcaccggcgg	Protospacer
**  ..********** ***** *******

157. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgcgcggcgtgccggtcggctccggcgg	Protospacer
**    **** ***.***************

158. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgatcggcctgctgctcggcaccggcgg	Protospacer
**  ..********** ***** *******

159. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcgcgcggcgtgccggtcggctccggcgg	Protospacer
**    **** ***.***************

160. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgcggcgggcctgctggtcggcttcggcac	Protospacer
**  ** ****************.****. 

161. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

162. spacer 6.13|927064|30|NC_018078|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

163. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

164. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP037868 (Hydrogenophaga pseudoflava strain DSM 1084 plasmid pDSM1084, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcg----gctccggcgg	CRISPR spacer
cgacgccggccggctggtcggagagctgcg----	Protospacer
*********** ********    *** **    

165. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

166. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

167. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgtcgccggcctgctgatcggcttcttctg	Protospacer
** *************.******.*  * *

168. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

169. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

170. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

171. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

172. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

173. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

174. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

175. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggtcctggcctgctggtcggcgccggcag	Protospacer
**.. *.*************** *****.*

176. spacer 6.13|927064|30|NC_018078|CRT matches to NC_019408 (Caulobacter phage CcrRogue, complete genome) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgtcatcggcctgctggtcgtcgccggcgc	Protospacer
** *..************** * ****** 

177. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 6, identity: 0.8

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgccgacctgctggtcggggcggactg	Protospacer
********.************  * *.* *

178. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP017941 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
caagctggtcggccccggcggcgctggcaa	Protospacer
*  **** *****.**************..

179. spacer 6.15|927160|30|NC_018078|CRT matches to MK937608 (Microbacterium phage Cressida, complete genome) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tcacctgtccggctccggcggcggtggcga	Protospacer
.*  ****.************** *****.

180. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP050083 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcgcttgg	Protospacer
*******.***** **********   .**

181. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP049733 (Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcgcttgg	Protospacer
*******.***** **********   .**

182. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP017592 (Pantoea stewartii subsp. stewartii DC283 plasmid ppDSJ01, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg--	CRISPR spacer
tctgctgttcggctgcggcggcg--agcagcg	Protospacer
.************* ********  .**.*  

183. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP008898 (Enterobacter hormaechei subsp. hoffmannii ECNIH3 plasmid pENT-576, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

184. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP023489 (Klebsiella pneumoniae subsp. pneumoniae strain ST101:960186733 plasmid p19-10_02, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

185. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP043515 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

186. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgctcggcaccggcggcgcgcttgg	Protospacer
*******.***** **********   .**

187. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_LT984809 (Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
catcgcgctcggcttcggcggcgctggcgg	Protospacer
* *  .*.******.***************

188. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP026371 (Klebsiella quasipneumoniae strain A708 plasmid pA708-3, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

189. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP050069 (Klebsiella aerogenes strain 035 plasmid p035_A-VIM-1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

190. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP039425 (Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgttcggcaccgacggcgccctccg	Protospacer
************* ***.******.  * *

191. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP009856 (UNVERIFIED_ORG: Enterobacter cloacae strain ECNIH5 plasmid pENT-784, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgttcggcgccgccggcgctattgg	Protospacer
 ************ *** *******. .**

192. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP039430 (Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgttcggcaccgacggcgccctccg	Protospacer
************* ***.******.  * *

193. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP040937 (Hymenobacter sp. DG01 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgt-tcggctccggcggcgctggcgg	CRISPR spacer
-ccgccgcgccggctccggccgcgctggcgg	Protospacer
 *.**.*. .********** **********

194. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cgtccagctcggcgccggcggcgctggcgt	Protospacer
* * * *.***** *************** 

195. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cgtccagctcggcgccggcggcgctggcgt	Protospacer
* * * *.***** *************** 

196. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP006588 (Hymenobacter sp. APR13 plasmid pHA, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgt-tcggctccggcggcgctggcgg	CRISPR spacer
-ccgccgcgccggctccggccgcgctggcgg	Protospacer
 *.**.*. .********** **********

197. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgtt--cggctccggcggcgctggcgg	CRISPR spacer
--cgccgctggcggcgccggcggcgctggcgg	Protospacer
  .**.*.*  **** ****************

198. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 6, identity: 0.8

cctgctgtt----cggctccggcggcgctggcgg	CRISPR spacer
----cagttggggcggctccggcggcgcgggcgg	Protospacer
    * ***    *************** *****

199. spacer 6.15|927160|30|NC_018078|CRT matches to MH029534 (Myoviridae environmental samples clone NHS-Seq2, complete sequence) position: , mismatch: 6, identity: 0.8

-cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
atttggt-ttcggcgctggcggcgctggcgg	Protospacer
 ..** * ****** *.**************

200. spacer 6.17|927250|36|NC_018078|CRT matches to MT723940 (Mycobacterium phage Ellie, complete genome) position: , mismatch: 6, identity: 0.833

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
cgttgtcggcaacggcggtaacggcgggggtggcgg	Protospacer
  * .************************ .*****

201. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_AP022566 (Mycolicibacterium alvei strain JCM 12272 plasmid pJCM12272, complete sequence) position: , mismatch: 6, identity: 0.778

gtcggcggactcgcggctgacgccggt	CRISPR spacer
cccggcggacgcgcagctgacgccgcg	Protospacer
 .******** ***.**********  

202. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 6, identity: 0.778

gtcggcggactcgcggctgacgccggt	CRISPR spacer
cccgtcggactcgcggctggcgccgta	Protospacer
 .** **************.*****  

203. spacer 10.7|2360821|30|NC_018078|CRT matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 6, identity: 0.8

gacggcgggttgttcttcggcgtgggcggt	CRISPR spacer
gtgagcgggttgttcctcggcgtggggggc	Protospacer
*  .***********.********** **.

204. spacer 10.7|2360821|30|NC_018078|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gacggcgggttgttcttcggcgtgggcggt	CRISPR spacer
gccggcgggttgttctgcggcgttggtgca	Protospacer
* ************** ****** **.*  

205. spacer 10.7|2360821|30|NC_018078|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

gacggcgggttgttcttcggcgtgggcggt	CRISPR spacer
gccggcgggttgttctgcggcgttggtgca	Protospacer
* ************** ****** **.*  

206. spacer 11.7|3738069|31|NC_018078|CRT matches to NC_009478 (Clavibacter michiganensis subsp. michiganensis NCPPB 382 plasmid pCM1, complete sequence) position: , mismatch: 6, identity: 0.806

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgaccacttcaccgccgtcgccgccggcg	Protospacer
. ** ***************.******* *.

207. spacer 3.4|369548|27|NC_018078|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.741

aagccgcccgagttcgcgagaccgaag	CRISPR spacer
tgaccgcccgagttcgcgagacgttgg	Protospacer
 ..*******************   .*

208. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MK977708 (Mycobacterium phage Fulbright, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

209. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MG099948 (Mycobacterium phage Philonius, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

210. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MH926055 (Mycobacterium phage Chewbacca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

211. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MT723932 (Mycobacterium phage Schnauzer, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

212. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to KU935726 (Mycobacterium phage Xerxes, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

213. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to KU935730 (Mycobacterium phage Pipsqueaks, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

214. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MH316570 (Mycobacterium phage Silvafighter, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

215. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MK524518 (Mycobacterium phage Smurph, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

216. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MK524515 (Mycobacterium phage Parmesanjohn, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

217. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MH697585 (Mycobacterium phage Gex, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

218. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to KM588359 (Mycobacterium phage Carcharodon, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

219. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MH697576 (Mycobacterium phage Aggie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

220. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MH697593 (Mycobacterium phage Tapioca, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

221. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to MG099936 (Mycobacterium phage Andies, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

222. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to NC_031243 (Mycobacterium phage Xeno, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

223. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to JN256079 (Mycobacterium phage Charlie, complete genome) position: , mismatch: 7, identity: 0.774

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
cgcgcgaacggcatcccgaaccgttgaccgg	Protospacer
 ************  ***********. *  

224. spacer 6.13|927064|30|NC_018078|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggtcgccggcctgctggtcgggttcggatc	Protospacer
 * ****************** *.***   

225. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

226. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

227. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ctgctgcagcctgctggtcagctccggcgc	Protospacer
* .*  *.***********.********* 

228. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

229. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

230. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ctgctgcagcctgctggtcagctccggcgc	Protospacer
* .*  *.***********.********* 

231. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

232. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

233. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

234. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

235. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

236. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

237. spacer 6.13|927064|30|NC_018078|CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgggaccggcccgctggtcggccccggctt	Protospacer
**. .******.**********.*****  

238. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gctgggcggcctgctggtcggctggggcgg	Protospacer
    * *****************  *****

239. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

240. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

241. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

242. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

243. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

244. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

245. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgcaggtcggcttcacctt	Protospacer
 ************* ********.*. *  

246. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

247. spacer 6.13|927064|30|NC_018078|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

248. spacer 6.13|927064|30|NC_018078|CRT matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

249. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

250. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

251. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

252. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

253. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

254. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

255. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

256. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

257. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

258. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

259. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

260. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

261. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

262. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

263. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

264. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

265. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

266. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

267. spacer 6.13|927064|30|NC_018078|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

268. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

269. spacer 6.13|927064|30|NC_018078|CRT matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

270. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

271. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

272. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

273. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

274. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

275. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

276. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

277. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

278. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

279. spacer 6.13|927064|30|NC_018078|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

280. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

281. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

282. spacer 6.13|927064|30|NC_018078|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

283. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

284. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

285. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

286. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

287. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

288. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

289. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

290. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

291. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

292. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

293. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

294. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

295. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

296. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

297. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

298. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

299. spacer 6.13|927064|30|NC_018078|CRT matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

300. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

301. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

302. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

303. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

304. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

305. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

306. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggacgccggcctgctggtcgactgggaaga	Protospacer
 *******************.**  *. *.

307. spacer 6.13|927064|30|NC_018078|CRT matches to HM560026 (Uncultured bacterium plasmid pTRACA45, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
acacgccgccctgctggtcggcttaggtcg	Protospacer
  ****** **************. **. *

308. spacer 6.13|927064|30|NC_018078|CRT matches to NC_010867 (Neisseria lactamica plasmid pNL3.1, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gaacgccgccctgctggtcggcttagtcgc	Protospacer
 .****** **************. * ** 

309. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
agacgccggcctgctgttcggcctcgaccc	Protospacer
 *************** *****..**.*  

310. spacer 6.13|927064|30|NC_018078|CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgggctcggcctgctgctcggcttcggcga	Protospacer
**.  .********** ******.*****.

311. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggc-tccggcgg	CRISPR spacer
gtcggccggcctgctggtcggcgcccggct-	Protospacer
    ****************** .*****  

312. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgacggcctgctggtcgacttcatccc	Protospacer
***** **************.**.*. *  

313. spacer 6.13|927064|30|NC_018078|CRT matches to KT997827 (Uncultured Mediterranean phage uvDeep-CGR0-KM15-C219, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gttcgccggcctgctggaccgctccgtggg	Protospacer
   ************** * ******  **

314. spacer 6.13|927064|30|NC_018078|CRT matches to AP021850 (Deinococcus grandis ATCC 43672 plasmid: pDEGR-1 DNA, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgtgtccggcctgctggtcgggttcggcac	Protospacer
**   **************** *.****. 

315. spacer 6.13|927064|30|NC_018078|CRT matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
tgacgccgccctgctggtcggcaaagtcga	Protospacer
.******* *************   * **.

316. spacer 6.13|927064|30|NC_018078|CRT matches to KT997829 (Uncultured Mediterranean phage uvDeep-CGR0-KM22-C158, complete genome) position: , mismatch: 7, identity: 0.767

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gttcgccggcctgctggaccgctccgtggg	Protospacer
   ************** * ******  **

317. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013634 (Rhizobium sp. N324 plasmid pRspN324d, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttcggggtcggctccggcggcgctggcga	Protospacer
..*   * *********************.

318. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP035001 (Rhizobium acidisoli strain FH23 plasmid pRapFH23c, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttcggggtcggctccggcggcgctggcga	Protospacer
..*   * *********************.

319. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP040820 (Paraoceanicella profunda strain D4M1 plasmid pD4M1B, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctccgcgctcggctccggcggcggtggcgg	Protospacer
*..  .*.*************** ******

320. spacer 6.15|927160|30|NC_018078|CRT matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

321. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

322. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP020909 (Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

323. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.*************** 

324. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP020951 (Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

325. spacer 6.15|927160|30|NC_018078|CRT matches to NC_021908 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

326. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP020441 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.*************** 

327. spacer 6.15|927160|30|NC_018078|CRT matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tttccggctcggcgccggcggcgctggcga	Protospacer
..* * *.***** ***************.

328. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP044080 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.*************** 

329. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

330. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

331. spacer 6.15|927160|30|NC_018078|CRT matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg-	CRISPR spacer
actgctgtccggctccggcggca-tgatgtc	Protospacer
 *******.*************. **..*  

332. spacer 6.15|927160|30|NC_018078|CRT matches to MN582086 (Siphoviridae sp. ctdEk19, complete genome) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gccggccttcgacttcggcggcgctggcgg	Protospacer
 *.* . ****.**.***************

333. spacer 6.15|927160|30|NC_018078|CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

334. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP022700 (Acetobacter tropicalis strain BDGP1 plasmid pAtBDGP1A, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gttcctccacggttccggcggcgctggcgg	Protospacer
 .* ** . ***.*****************

335. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

336. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

337. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
ctgcctggtcggctccggcggcgctcgtcg	Protospacer
*.  *** ***************** *. *

338. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP031082 (Paracoccus yeei strain CCUG 32053 plasmid pYEE4, complete sequence) position: , mismatch: 7, identity: 0.767

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tctcgggctcggccccggcggcgctggcgc	Protospacer
.**   *.*****.*************** 

339. spacer 6.17|927250|36|NC_018078|CRT matches to NC_022087 (Mycobacterium phage AnnaL29, complete genome) position: , mismatch: 7, identity: 0.806

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
cgtgatcggcaacggcggaaacggcgggagctgggg	Protospacer
  **************** *********. * * **

340. spacer 10.6|2360776|27|NC_018078|CRT matches to NZ_CP015006 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence) position: , mismatch: 7, identity: 0.741

gtcggcggactcgcggctgacgccggt	CRISPR spacer
acacaccgactcgcggctgacgccggc	Protospacer
..  .* *******************.

341. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

342. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cccacccacttcaccgacgtcgccgccgacg	Protospacer
  *.************ ***.******* *.

343. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP042263 (Litoreibacter sp. LN3S51 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.774

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atccgccatttcaccgccgttgccgacgccg	Protospacer
* *  ***.**************** **.*.

344. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttggtgtcgatctcgatctggccgttgcccgca	Protospacer
  * **.*****.**************** *..

345. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.******* 

346. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
atgctgccgaccccgatctggtcgttttcgact	Protospacer
* ********.**********.**** .**.. 

347. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtcgaccttc	Protospacer
 ***************** ** ***.* *  * 

348. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.758

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
agctggttgatgccgatctggccgctgccggtc	Protospacer
** . *..*** ************.******* 

349. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgacgccggcctgctggtcgggctgacctc	Protospacer
********************* .. . *  

350. spacer 6.13|927064|30|NC_018078|CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ccgcaaactcctgctggtcggcgccggcgg	Protospacer
* .*.    ************* *******

351. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgatgccggcctgctggtcggggttcccag	Protospacer
***.*****************  ..  *.*

352. spacer 6.13|927064|30|NC_018078|CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ccgcaaactcctgctggtcggcgccggcgg	Protospacer
* .*.    ************* *******

353. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ccttcagggcgtgctggtcggctccggcgc	Protospacer
*  .   *** ****************** 

354. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_KY126370 (Enterobacter cloacae subsp. cloacae strain MN201516 plasmid pOP-I, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

355. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP054625 (Cupriavidus gilardii strain FDAARGOS_639 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggccgccggcctgctgtgcggctccgcgct	Protospacer
 * *************  ********    

356. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgatgccggcctgctggtcggggttcccag	Protospacer
***.*****************  ..  *.*

357. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_LT960615 (Hartmannibacter diazotrophicus strain E19T plasmid HDIAp1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
gttcaccgccctgctgatcggctccggcat	Protospacer
   *.*** *******.***********. 

358. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP046347 (Citrobacter portucalensis strain FDAARGOS_738 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

359. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP044100 (Citrobacter werkmanii strain FDAARGOS_616 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

360. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP032156 (Mycobacterium sp. ELW1 plasmid pELW1-1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
aatcgccggcctgctggtcggtgccgcggt	Protospacer
 . ******************. ***  * 

361. spacer 6.13|927064|30|NC_018078|CRT matches to KY555144 (Caulobacter phage Ccr5, complete genome) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
ggtgatcggcctgctggtcgtcgccggcgc	Protospacer
 *  ..************** * ****** 

362. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_KP873172 (Pseudomonas aeruginosa PAO1 plasmid pAMBL1, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

363. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP045203 (Citrobacter sp. NMI7904_11 plasmid pCTEL-2, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

364. spacer 6.13|927064|30|NC_018078|CRT matches to NC_021492 (Enterobacter sp. R4-368 plasmid pENT01, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

365. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP022156 (Escherichia coli strain ABWA45 plasmid pABWA45_2, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

366. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP024682 (Citrobacter freundii strain UMH14 plasmid pUMH14_2, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
catggccggcctgctgctcggcaccgggac	Protospacer
*.  ************ ***** **** . 

367. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 8, identity: 0.733

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cgatgccggcctgctggtcggggttcccag	Protospacer
***.*****************  ..  *.*

368. spacer 6.15|927160|30|NC_018078|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cgaccatctcggctccgacggcgctggcgc	Protospacer
*   *  .*********.*********** 

369. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

370. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gccaccccgcggctccggaggcgctggcgg	Protospacer
 *..*. . ********* ***********

371. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcaccggcggcgctggcga	Protospacer
. *   *.***** ***************.

372. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcaccggcggcgctggcga	Protospacer
. *   *.***** ***************.

373. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

374. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

375. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

376. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

377. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

378. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

379. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

380. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcgccggcggcgctggcga	Protospacer
. *   *.***** ***************.

381. spacer 6.15|927160|30|NC_018078|CRT matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
tatcaggctcggcaccggcggcgctggcga	Protospacer
. *   *.***** ***************.

382. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgctgatcggctccggcgccggcttctc	Protospacer
******* ************ ** .  *  

383. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gctgctgtgcggctccggcggcaaccccga	Protospacer
 ******* *************. .  **.

384. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_LR134452 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
cctgatgttcgactccggcggcgacgcacc	Protospacer
**** ******.*********** .*    

385. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 8, identity: 0.733

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gcaccgcgccggctccggcggcggtggcgg	Protospacer
 *  *   .************** ******

386. spacer 6.17|927250|36|NC_018078|CRT matches to MG770216 (Mycobacterium phage Rem711, complete genome) position: , mismatch: 8, identity: 0.778

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
attcggcggcaacggcggcaacggcgcggccggcgc	Protospacer
..* . ************.******* ******** 

387. spacer 6.17|927250|36|NC_018078|CRT matches to KY087993 (Mycobacterium phage Hammy, complete genome) position: , mismatch: 8, identity: 0.778

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gcagatcggcaccggcggtaacggcggcggtgcagc	Protospacer
** ******** *************** * .*  * 

388. spacer 6.17|927250|36|NC_018078|CRT matches to MF140406 (Mycobacterium phage DarthP, complete genome) position: , mismatch: 8, identity: 0.778

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gcagatcggcaccggcggtaacggcggcggtgcagc	Protospacer
** ******** *************** * .*  * 

389. spacer 7.16|1291513|29|NC_018078|PILER-CR matches to MK599315 (Pseudomonas phage PA1C, complete genome) position: , mismatch: 8, identity: 0.724

cttgaataacgcgcagtgaatttcgcgga	CRISPR spacer
tgaaaataaagcgcagtgtatttcgcgtc	Protospacer
.  .***** ******** ********  

390. spacer 11.7|3738069|31|NC_018078|CRT matches to CP033373 (Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ttagcccacttcacggccgttgccgacgcgg	Protospacer
   *********** ********** **. .

391. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

392. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

393. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

394. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

395. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

396. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

397. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

398. spacer 11.7|3738069|31|NC_018078|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

399. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

400. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
cgcaactccttcaccgccgctgccgccgtct	Protospacer
 .*. *. ***********.********** 

401. spacer 11.7|3738069|31|NC_018078|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

402. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

403. spacer 11.7|3738069|31|NC_018078|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
gccgcccacctcaccgccgtggccgcgctgg	Protospacer
. *******.********** *****  * .

404. spacer 11.7|3738069|31|NC_018078|CRT matches to NZ_CP027299 (Streptomyces sp. SGAir0924 plasmid unnamed_5) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
ctcggtggcttcgccgccgtcgccgccgtca	Protospacer
  ** . .****.*******.**********

405. spacer 11.7|3738069|31|NC_018078|CRT matches to NC_014213 (Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence) position: , mismatch: 8, identity: 0.742

aacgcccacttcaccgccgttgccgccgtca	CRISPR spacer
atcgcccacttcaccggcgtttccgaccctt	Protospacer
* ************** **** *** * .. 

406. spacer 13.5|3985226|36|NC_018078|CRISPRCasFinder matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 8, identity: 0.778

atcggcaactccggcaccaacaacatcggcttgttc	CRISPR spacer
agcggcaacaccggcaccaacaacaccggcaccgcc	Protospacer
* ******* ***************.**** .  .*

407. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatcccgatctggccgtcgccggcc	Protospacer
  *.  .******************.*****. 

408. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP016287 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

409. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

410. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 9, identity: 0.727

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
cggctgccgatcccgatcaggacgtctaccttc	Protospacer
 ***************** ** ***.  *  * 

411. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to NZ_CP014964 (Geobacter anodireducens strain SD-1 plasmid pSD, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
ggaacgaacggcaagccgaaatgttggtgga	Protospacer
.* .**************** .*****    

412. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to NC_015974 (Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. * 

413. spacer 4.1|692359|31|NC_018078|CRISPRCasFinder matches to NZ_CP005085 (Sphingobium sp. TKS plasmid pTK1, complete sequence) position: , mismatch: 9, identity: 0.71

agcgcgaacggcaagccgaaccgttggaccc	CRISPR spacer
taagcgaacggtaagccgaaccgctgaggcg	Protospacer
 . ********.***********.**.. * 

414. spacer 6.13|927064|30|NC_018078|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.7

cgacgccggcctgctggtcggctccggcgg	CRISPR spacer
cggcgccggcctgctggtcggactgctcac	Protospacer
**.****************** ..   *. 

415. spacer 6.15|927160|30|NC_018078|CRT matches to NC_005241 (Cupriavidus necator H16 megaplasmid pHG1, complete sequence) position: , mismatch: 9, identity: 0.7

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gaccacgttcggctccggccgcgctcgcgt	Protospacer
  .  .************* ***** *** 

416. spacer 6.15|927160|30|NC_018078|CRT matches to NZ_CP039289 (Cupriavidus necator H16 plasmid pHG1, complete sequence) position: , mismatch: 9, identity: 0.7

cctgctgttcggctccggcggcgctggcgg	CRISPR spacer
gaccacgttcggctccggccgcgctcgcgt	Protospacer
  .  .************* ***** *** 

417. spacer 6.17|927250|36|NC_018078|CRT matches to MF140398 (Mycobacterium phage Amohnition, complete genome) position: , mismatch: 9, identity: 0.75

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gcagatcggcaccggcggtaacggcggcggtacggc	Protospacer
** ******** *************** * ..  * 

418. spacer 10.7|2360821|30|NC_018078|CRT matches to NZ_CP022197 (Celeribacter ethanolicus strain TSPH2 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

gacggcgggttgttcttcggcgtgggcggt	CRISPR spacer
cggagcgggttgttcgtcggcgtggagcga	Protospacer
 . .*********** *********.  * 

419. spacer 11.5|3737928|34|NC_018078|CRT matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
attgagatccgcgacgatgggtgtggcgccggcg	Protospacer
.**    .********.**** ***********.

420. spacer 11.5|3737928|34|NC_018078|CRT matches to MG812496 (Gordonia phage SallySpecial, complete genome) position: , mismatch: 9, identity: 0.735

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gcgcaccaccgcggcggtgcgggtggcgccggcg	Protospacer
*. . *. *****.***** *************.

421. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

422. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtactcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

423. spacer 3.6|369683|33|NC_018078|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 10, identity: 0.697

aggctgccgatcccgatctggccgttgccggtg	CRISPR spacer
ttgtattcgatgccgatctggccgtcgccggcc	Protospacer
  *.  .**** *************.*****. 

424. spacer 6.2|926560|39|NC_018078|CRT matches to NZ_CP044080 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.744

cggcgcgggcggggccgtcacgggaaccggcgccaccgg	CRISPR spacer
cacgggggccggggccgccacgggaaccggcgccccgcc	Protospacer
*.  * ** ********.**************** *   

425. spacer 6.17|927250|36|NC_018078|CRT matches to MN369764 (Mycobacterium phage Rahalelujah, complete genome) position: , mismatch: 10, identity: 0.722

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
atctggaggcaacggcggtaacggcggggccagcac	Protospacer
... .  ************************.**. 

426. spacer 6.17|927250|36|NC_018078|CRT matches to NZ_CP025548 (Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.722

gctgatcggcaacggcggtaacggcggggccggcgg	CRISPR spacer
gaccggcggcaacggcggaaacggcggcgccgcagc	Protospacer
* . . ************ ******** ****  * 

427. spacer 7.4|1290631|34|NC_018078|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022335 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49c, complete sequence) position: , mismatch: 10, identity: 0.706

tcgcaagcgccgtgcttccagtgatcgccttcta	CRISPR spacer
gtgccgccgccgagcttccactgatcgccttgcc	Protospacer
 .** . ***** ******* ********** . 

428. spacer 8.10|1293996|35|NC_018078|CRT,PILER-CR,CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 10, identity: 0.714

gccccgtggatggcggatgcgttgtgcgcgcaagt	CRISPR spacer
accgtgtggatggcgaatgtgttgtgcgcggtgac	Protospacer
.** .**********.***.**********  ...

429. spacer 11.5|3737928|34|NC_018078|CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cagcgcggccgcgtcggtgggggtggcgcccgcc	Protospacer
   . *  ***** **************** ** 

430. spacer 11.5|3737928|34|NC_018078|CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

431. spacer 11.5|3737928|34|NC_018078|CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

432. spacer 11.5|3737928|34|NC_018078|CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 10, identity: 0.706

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
gagaccgcccgcgatggagggggtggcgccgagc	Protospacer
*   .* *******.** *************.  

433. spacer 11.9|3738201|37|NC_018078|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.73

cttgccggcggtgccggcgaccgcggtgccgccggtg	CRISPR spacer
ggagacggcggtgccggagaccgcggtgtcgctgccc	Protospacer
   * ************ **********.***.* . 

434. spacer 11.5|3737928|34|NC_018078|CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 11, identity: 0.676

gttttctcccgcgacggtgggggtggcgccggca	CRISPR spacer
cgcccccggcgtgacggtggaggtggcgccggcc	Protospacer
  ...*.  **.********.************ 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1292015 : 1331492	40	Burkholderia_virus(40.0%)	tRNA,integrase,transposase	attL 1291965:1292024|attR 1331861:1333216
DBSCAN-SWA_2	1430630 : 1443376	20	Mycobacterium_phage(57.14%)	protease,head,capsid,terminase,integrase	attL 1434287:1434314|attR 1443911:1443938

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_018078|1292015:1331492|DBSCAN-SWA
CATGTCAGGTGGTTCATCGAGGAGGTACCCGCCGGAGCTGCGTGAGCGGGCGGTGCGGATGGTCGCAGAGATCCGCGGTCAGCACGATTCGGAGTGGGCAGCGATCAGTGAGGTCGCCCGTCTACTTGGTGTTGGCTGCGCGGAGACGGTGCGTAAGTGGGTGCGCCAGGCGCAGGTCGATGCCGGCGCACGGCCCGGGACCACGACCGAAGAATCCGCTGAGCTGAAGCGCTTGCGGCGGGACAACGCCGAATTGCGAAGGGCGAACGCGATTTTAAAGACCGCGTCGGCTTTCTTCGCGGCCGAGCTCGACCGGCCAGCACGCTAATTACCCGGTTCATCGCCGATCATCAGGGCCACCGCGAGGGCCCCGATGGTTTGCGGTGGGGTGTCGAGTCGATCTGCACACAGCTGACCGAGCTGGGTGTGCCGATCGCCCCATCGACCTACTACGACCACATCAACCGGGAGCCCAGCCGCCGCGAGCTGCGCGATGGCGAACTCAAGGAGCACATCAGCCGCGTCCACGCCGCCAACTACGGTGTTTACGGTGCCCGCAAAGTGTGGCTAACCCTGAACCGTGAGGGCATCGAGGTGGCCAGATGCACCGTCGAACGGCTGATGACCAAACTCGGCCTGTCCGGGACCACCCGCGGCAAAGCCCGCAGGACCACGATCGCTGATCCGGCCACAGCCCGTCCCGCCGATCTCGTCCAGCGCCGCTTCGGACCACCAGCACCTAACCGGCTGTGGGTAGCAGACCTCACCTATGTGTCGACCTGGGCAGGGTTCGCCTACGTGGCCTTTGTCACCGACGCCTACGCTCGCAGGATCCTGGGCTGGCGGGTCGCTTCCACGATGGCCACCTCCATGGTCCTCGACGCGATCGAGCAAGCCATCTGGACCCGCCAACAAGAAGGCGTACTCGACCTGAAAGACGTTATCCACCATACGGATAGGGGATCTCAGTACACATCGATCCGGTTCAGCGAGCGGCTCGCCGAGGCAGGCATCCAACCGTCGGTCGGAGCGGTCGGAAGCTCCTATGACAATGCACTAGCCGAGACGATCAACGGCCTATACAAGACCGAGCTGATCAAACCCGGCAAGCCCTGGCGGTCCATCGAGGATGTCGAGTTGGCCACCGCGCGCTGGGTCGACTGGTTCAACCATCGCCGCCTCTACCAGTACTGCGGCGACGTCCCGCCGGTCGAACTCGAGGCTGCCTACTACGCTCAACGCCAGAGACCAGCCGCCGGCTGAGGTCTCAGATCAGAGAGTCTCCGGACTCACCGGGGCGGTTCACCCCGAGAGGGGACGGAAACTCGGGGAGCCGATCAGCGACCACCGCACCCTGTCAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCTTCAGCACCACCATCATCCGGCGCCTCAGCTCAGCATGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCCTTCGACGCCGGATTCGTGATCTCTTCCCGCGGATAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTGCCCCGGCGTTTAGCGATCACAACACCAACTAATGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCAGCGAAATACAGGCTCCACGACACGACCACAACGCGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTCTTGACGATGCGGTTGCCCCGCGCCCTTTTCCAGCCGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACAGGTTCGCGTCAGACAGGTTCGCGTCGATCAAGTCCGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTTTATCACTCCCGACCAAATAGGTATCGGCGTGTTCAAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACATTTTGAGCGCGAACTCGTCCACAGTCCCCCTTTCAGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACGCCCCGTGGATGGCGGATGCGTTGTGCGCGCAAGTGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCCGACGATGGCCAGTAAATCGGCGTGGGTAACCGATCCGGGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCTGACGGCACGGAGCTTTCCGGCTTCTATCAGGTAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACCCTCATGGTGGGACATGGACGAGCGCGACTATCGGGGTCGTCGGACCCAAAACCCCGAGAGGGGACGGAAACTGGACGCAGAATCGCACCGGGTGCGGGAGGTGCAGCAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACGCATATCGCCCGCCACACCACAGCCACGCTACTGCTCCATGTCCTCAGACCCAAAACCCCGAGAGGGGACGGAAACACACCGCCGATGACAGCTATGTCCGAGTGACATCCTCCCAGTCGTCAGACCCAAAACCACGAGAGGGGACGGAAACTTGAACCGCCCTTCGCGCGGTGTTTCGGCCGTGCCCGAGTCGTCAGACCCAAAACCCCGAGAGGGGACGGAAACTACGACGACTGGGTCGCCACCGCGTCTGTTGACCGGCATTCAGGATGAGCATGATGGCGGCGTTGACGGTGAGGACGTTTGGTCATGAAATGACCCCGCCGGGAGATGTCCGGCGGGGTCGGTGGTGTTCGGGGTGTCGGTGTGGTGTTCAGTCTGCCGTGACTTCGGCGATGGCGGTGCGGGTGGTGGATTCGTCGACGATGGCCTTGTCGGCGGCGAAGGCGGCGACGAGGGCTTGCAGGGCGAGGTTGTTGACCGCGCGGGGGTAGCCCCGGCTGGTCTGGTGGATCAACCCGATGGCGTCGTCGGAGAACAGGGCATCGTCGCGTCCGGCTAGCTTGAGGTGGTGGCGTAGGTAGCTGCCGGTGTTGGTGTCGGTCATGGGCGGCATGGCATATCGGAGTCCGATGCGCTGGTCAAGCGCGGCGAGCACGCCGAGTTTCATCCGCCGCCGCAGGGTGGGTTGGCCGATGAGCAGGCAGGCGAACGGGCTTGACGAGTCGAGGTCGTGATTTGTCAAGAGCCGCAACGCCTCCAGTTGGTCATAGCCGAGCAGGTGCGCTTCCTCGACGACCACGACGGGGGTGCGTCCGCGCTCGGCTTGTTCGGCGGCTAGCGCGTCGGCGGCCTGTGGGGCCAGGGTGGCGTGGTGGGTGAGGGGTTGTCCGCCGAGCGAGGCGACGATGCGGTGGTGGATGCCCTGGACGCCGACGGTGGGGTCGGGCAGGTAGATGATGGTGTGGCGGCTGCGATCCAGGCTCGCTAGTGCGGCGCGCACGGCGACGGTCTTGCCGGCGCCGACTTCGCCGGTGATGACGCCGATGCGGCGGTCGGCGATGCACCAGCCGATGCGGGCGACCGCTTCGTTGTGCGCGCTGTGGCGATGCAGCATGCCCGGTGCCAGATCGCGGCCGAATGGCATGCGCGAAAAACCGTAATACGAGATCAGTTTGTGCATCATTTCGGTTGGGCCTCCTGGCCGGTGAGCAGGTCGAGCTGGCCGGGGATCTGATCGGCAGCCCCGGTGAGGGCGGTGTAGTTGACGCCGCGGGCGAGTTCGGCTGCGTGCGCGGTCTCGATTAACTGCGCGTAGTCGATGCCGCTGGGTTTGGGCGGTGCGGTGGGGGTTTCGGGTTTGGCTTTCGGGTGTGAATGGCGCCCGATGTGATACGGAATGGCCCGCCCCATCGGCGCGCCGGCCAGCCGCACCTCGATGCGGGTCAAATCGAACGGGTCGAACACCAACTCCACTTTCCGGCCGACCAGCGCCGGGTCGATCTCGTAGCGGTTGCCGTGCAGCGAGACGGTGGCGGTCTTGGTCACGCGGCGGTGCTCCTCCCACAGGAAGGCCTCGGTGAGCGTCTCGGGGGCGGGCAGCGGGATGGGGCCGCCGGCTGACCAGCGGGCCAGCGGGGTCTGCCCGGTTTCGGAATGCACGCTGCGGTGATAAACCGTTTCGACCCAGGCCGTAAACAGCCGATTCAACTCGGCCAGATCAGCGACGTAATGTCGGCCGACGACGTCGGGTTCGCCGGTGATCTCGACCAGGAACTGCTCGCGCACGGTGCGGAAGAACCTCTCTATCTTGCCCCTGCCTTGCGGCCGACCTGGCGTGGAATGAACAAGGCGCACACCGAGTTTCGCGCATGCCCGCAACAACCACGCATCCACATAGGGCGAGCCGTTATCGACATACACCGCGTTGGGCACGCCGCGGGAGGCCAGCGCCGGGCGCAGTGCGGCGGCCAGCCGCACCGTGTCCTCGGCATGGCCCCACCGGTAGCCGGGCACCAACCGGGAATGGTCGTCTAAGAACGCGAACAGATAGGTCTTGCGGAGATCAATCCGTATGCCGTGCAACACATCCCCGGTCCACAGGGCGTTCGGGTGCTCGGCTTCGAACCGGCCGAACACCGCCGGCGCCGACCCGGTGGTGGCGCCGGTGAGCCCGAGCCGGTGGAAGTTGCGTTGCAGGGTGCGTTCATCGGGCGCCCAGCCCAACTGGGTACGCAGGATCCGCCGGATTGCCGCCGCCGTGCGCTGCGGGTTTTCCCGCCGCAGCGCCACCGCCAGCTCCAGCACCTCGGCCGGGGTACGCGGTGTGCACTGGCGTGGGTTGGGCACCAGCGCGTCGAACCCGCCGGCCCGCCAGCCCCGGATCCAGCGGTCGATGGTTTGGCGGCTGATGCGCACCCGCCGCCCGAACGGATCGGTGTGCTCGCGTGAGGCCAACTCGCGCACCATCTTTCCCCGCTGCTTGGTGGAATGCGCCGCATCGGCGGCCTCCCAAATCAACTGGTAGCGAAACAACCCGATCGCCCTCGCGCGCTCCGCGCGCACCTTCTCCTCGTCATCGCCGACCGCCACCGGCCGCTCCTTTCCATTTGCTGTCTGTCAAAACACACGACAGCGCACAGGTTTACGGCCCGATCGACGGCTACGGCAGGGTCGACTCGTGTTGCACCCACTCGCCGGGCCAGCCCGGCGCCAACAACCGCCCACCTGACACCGCTACCGCGGTCTCAGCCAGCGACACCGTGGGCAGCGAAAACCGGCGCCCGATGGCAGCTGCGAGCGCGCCGATCGCCACCACCGCATCGACGAACCCGCCGCCACCTGCATCCGGCATCACCGGATCGGCATCGACCGCGCACAGCCACACCGTGAACACCGACCGCACCGCCTCGACACGCTCGGCAAACCGGCGCAGCCAGCCCCGCACCGTCTCCGCCGGGCGAGCCACATCCGTGGCGATCCGGCGGAACCCGACCCGGCTGGTGGCCTTCGCCGCCAGCGCCGACACGATCACCGCCGCCGTGTCGGCGCGGCGCAGCAACGCGCTCACCGGCAACAACACATGCGTCACCCCGCACCCGGTGCACCGCGACCGACGCGGGCACAACTCCACCGGACCAGCCGGGCCGCGTAACTGCCGCGACCGAGCCCGGCCCCAGCCCGCCAGCACACCCCCGCAAGACGGGCAGCTCAGCTCACCGGCCGCCAGCCGACGCTCGACTTGATCGACATCTGCTTCTACGGTGACCACTGCGCCTCCAAGCGCACACAGGCGGCCCTCCCGTAGCACTCCGGCAAGAGACGACGGGAGGGCCGTCGCCTACCAATGACCTGATCACCGAGCCGCCCCGGCACTACAAACAACAAACCCGGGTACGGCAAGCCCCCGCGCTGCTCACCGTCAGCGCCGGAACCGGTGTCCCTGTCGTACTAGAGGAACTGGCCAAACTAGGCCGCACCCTGTGGCGCTGCCGCCACGATGTGCTGGCCTACTTCGACCACCACGCGTCCAACGGGCCCACCGAAGCCATCAACGGACGACTGGAAGCCCTATGCCGTAACGCCCTCGGATTCAGAAACCTCACCCACTACCGAATCCGTTCACTACTGCACTGCGGCAACCTGGCTCAGCTGATCCATGCACTCTGATTCCGGAAGAGCCATTAAAGCTCATCGGTTCCACTCCACCAGCTTCATCCGCACGTCGACACCTGGTCCGAGCTTCTGCTTGAGGCCCTGCATAAAACCCCACTGACGCACCGCCTGGTCAGCCAAACGCCGACATAGCCGCTCCACTGCGTCGACCGGCTGGTTTTCATAGTCGCTATCACCGCGCGTATCCAACGTGTCCGTCGCGGAAGCGACCGGTCCCTCGTTCTCTAGCAGCAGCACCGCGAGCTGACGCTTGTCCACCAGCACCACCCACCGCATCTGTGCGAGCAGTTTGGGGAGCGTCGTATCGTCCCTGGCTGCGTACGTCATGTGCGTTCCTGCCTAAGCTCCTTCAGTCCCACGCGAATACCAGCCCGGCCGCGCTCCCGATGCACGGTAGGCGCCTGGTGCTGGCAATAGTTGGTGTCAAGCGATTATCGGTATATCGGCCACGTCTCTAAGTATGCGTCAATTGCTCGTTCGATTTTCAACCCATAATCATTCGGAACCCAATCAGGTCCAAAGGTCTTCATCAAGGCGTCGGAAAGCACGTCGATAACAGCGTCGCTCTGTTCGTTGGTTGGCTTCTCTGTGCGCCGAAGCTCGTCGAAGAGAGCGGGATTACGATTCTCTAATTCTTGCTCGATCACGGGACGGTGCTCCGTTGAAATAGCATCGAGAACGTTGCTCACGGATTTCTCCATCCAGCCCGGCTGTTCGCCCAGGCGGTTACCACTTGGCCATCTTTGTTTAGGACCACTGTTGCGTCTTTCCCAACGTACACGTAAGCGCCTCTACCAAGCTCATCCACTTTAAACTGGGGCGGCCCAACAGGATTCGCAACAGCATCCGAGGTGCCTCACGTAGAAGTGAGCGCGAAGCGTGGCTGGTGCCTCACGCATAGTGAGCGCGTGGGGGGCTTGCATTACTTCGCCTTGGCCAATCGGTTGATTGACGGTTGCAATGATTGCAGGTCGATGTGGCGGGCGGTGGCCAGGGCCTCGGTCTTGGTCTTGGCCAGGTCGAGCAGCTGCATTTGGATCGCGTTGATCTGGCGGGTCAGATCGGCCGGGTTGAAGCCTTCGATTCGGGCGGCCACGGTCGAGAGTTGCTGTGCATCAAGGACGCCCGATGCCTGCAGGCGCTGCCATGGGGTGGCCGGCTTGTCATAGATGCGCTTGCGGCGACCGTTGACGGTGCTGGTGTAGCCGACGGGCTTTTTGGTCGGGGTGAAGAAGTTGCACCGCAGCGACACCAACGGCCATAGCCGGTTGAGCAGCTCCAGCTCTTCGCCGGTGTCATAGCGCCAGTAGAACGCGTGTTTGCGCACCACATGATTGTTCTTGGACTCGACATGGGCCTGGTCGTTCTTCTGGTACGGCCGCGAGCGAGTCTGGGCGATGTCGCGGGCCTGCAGCCAGCCGGCGACGTCGTGATTGATGAACTCGCCCCCGCAGTCCGAATCGAAAACCGTCATCGGGAATGGGAACCGCTGCTGGCACTCCTTGATGCCCTCGAGGATCCACTTGGCCGCGTTGTTGCGGATCGAGGCGTTCTCGGTCCAGCCGGTCACCAGATCAGTCATCGTCAGGGTGCGGGCGAACTCGCCGATTAGACTCGGGCCGCAGTGCGCCACAGTGTCGGCCTCGATCACCCCCGGGACCTTGGGCGCCTCATCCGAACAGGTGTGGATGGTGATCGAATTACGCAGCAATGGTGAGGGTTTGGTTGTCGAGATGCCTTTGATGCGCATCCGCTCGCGGGCGGGTTTGAGGTAGCGGTCCACGGTGGCCGCGCTCATCGCCTTCAACTCCGCCACCGCCGCTTCGGTGGCGAACGGCTTGTCAAGATCACCGGCGGCGGCCACAAGCGGCAGCCACAGCTCGAGCATCACCACCAGGTACTTGCCGCACGGCATGCCCATCAAGGCCCACACGTGCTCTAAAAGCGCCCTGGCGTCGTCACTGAAGCCCCGCGCCCGCAGCCTGCGCCCGTCGACCTGCTCGGCCGGCTCCGGCAGCCCCGGGCCGGTCAGCATCCGCCGGGCCGTCGAACGACCCATCCCGGTGGTGGACACCACCCGATCCAGGATCTTGGTCTTATCCGCCTTCGATGCCGAAGTGCCTCACTTAAAAGTGAGCGCGAAGTAGGTGTGGCTGGTGGGCAGTTTCCTCGTGTCCCGCCGCCGCGACACGGTGACCGTCGGCTGGCACACGAGCCGTGGGGTTGGCGGCCGACGACGGCGCTGGTCAGGTGTGCCGGAACCGGTCGATGATCGCTATTGCCGGTTGATATGGCGCTTGCCGGACCAGCCCCGGTAGCCGATGTAGCCCATCAACACGGCGAGGCCTCCGGTACTGATCAGGCCCAGCGTCGAGCCGTGGGTGCACACATTTAGCACGAACAGCGCCAGGAACAACACCGTCATCACTGAGTAGAACGCCGGGCCGTACCGGGGGTTGGTTTTCACGTGCGCGTCCTCACCGCCCGGGCTGGAAAGCCATCAGGGAGTGTCCCTGCGGCCCAGTGCGGCATGCGATTCGCCCCTGGTAGGGCTGTCGCCTTCAACTCGGCCACCGACGCCTCGGTGACGAGCGGCTTGTCAAGATCACCGGCAGCGGTCAACAGCGGCAACCACAGGTCATGCATGACCACCAGGTACTTGCCGCACGGCATGCCCATCAAGGCCCACACGTGCTCCAGCAGCGCCCTGGCTTCGTCGCTGAAGCCCCGAGGCCGAAGGCTACGCCCGTCGACCTGCTCGGCCGGGCCCGGCAACCTCGGGCCGGTCAACATCTGCCGCGCCGTCGAGCGGCCCATCCCCGTGGTGGCCACCACCGGATCCAAAATCTTGCCGTTGCCCCTCCCCATCACCGACGACAACAACAACGAGGCCATTCGAGGCGATCGATCGGCAGCACGTCGCCAAGCGACGATAGCGCTTCATACTCCCAGCGCCCGCGCGATGTCGCTGATCCGCCGGTAGAGGCGTCGACCCTCGAGGGGCAAGAAGCCGTGGTGACCGTAGAACTCGGCGGCGCGGTCGTCGATGGCGTCGACGACCAGGGCGCGGGCGCCGTAGTGCCGGGCACCGGCCACGGATCGGATGAGGGCATCGAGGAGAAGATCGCCACCGAGACCGGTGCCTTGCTCCTGCCGGTCGAGCGCCAGGCGAGCGAGGACGAGCACTGGGATCGGGTCGGGTCGGGTTGGCCCCGGCCCGGCCGCGATGGCACCCGGATCCGCTCGATGCTCCCCATGGCGAGCGCGTAGAACCCAACTACCCGCCGGCCTCGACAGAGCACCCACGTAGCGGCCGTGCCGGCGGCAGCCGCGACGGGCGCGACTCGGCGCAGCCAGTGGTCGAGAACCTCAACATCGCTGGAGAAGCGCGCCGTGTCGTGCCGGTCCGGGTCCAACAGCTCGACGGGGCCGAGCGCGGGGGTGCTCAATGGGGGGGAATGCGGCTCTTCCGTCTGGCGAGGCGCACCAATTCGGGAGCCGCCTCGTCGGGCTCGTCGAGCGCGGCGACGAAGCGGCGGAAAGCGGCCTCGGACAGCTCGATCCGGTTGGCCCGGGCCAAGAGATCGTGGGCGTGGTCGACCGCGGCGGACAATACGAACCCCGACAGGCTCTGGCCGGTGAGCGCGGCGGCGTGGCGAAGGGCCTGCTCCTGTTCAGGAGACAGGCGGAAGTTGAGGCGACCAGTCAGAGTCTCGGGCATGTACGTAATGTAGACGTACTTCGTCGACGTCTGATCGGTGTTGATGCGGCGAGAAGCGTTTCTCCGTGGCGGCCGAACGAGGTTCTGTTGTTCCCGACGTTCGCGCATCGCCACTCCGAGCGCGTCCGGCTGGTCGGAGTAACTCAGTTCCGCGGCCTCGGTGCGCAGTCCGACTAGGCTCGGGCAGGTCATGGCACGTCAACCTCTGGAGCAGCGGGTGGCCCGGGCGGCGCAGGCGGCGCTGGCCCGACAGCGGTTCGTCAGCGCGATCGATGTGCTGCTCGGCCTGGGCTGGCTGGCGCCCTCGCATGTCGACCAGTGGCGGCAGGGCCGCGTCGACTCGCTGGAGCAAGTCGTACAGGCCAACCTCAGCAAGATCACCGCCGTGATGGCCGCGTTGCGGCGCTGGGCCCGCGACCGGGGGCTCAACCCGTCGGAGACCGATTACGTCGCTCGCACTCGGGACCGCCGTCGGCTGCGGTTCAGCGTCACCGGCGAGGACGCCATCGAGCGCGCGTATCGCACGCATTGGGTGTCGCCGGAGCTCTCGGAGCGTGCGGTCGCGCGGCAGAGCCGGCGCCCCGATTTGGTCGTGATCATGCCGGTCAACGACTGGTCATGCGCGTCGTGTGGCGGCAGCGGTGACCTGATGTTCCTTGAGGACGCGGGGCCGTTGTGCCTGGACTGCGCGGACCTTGGCCATCTGGTCTTCTTGCCGTCCGGGGACGCCGCGCTTACCCGCCGGGCCAAGCGGGCGAGCCGGCTTTCGGCGGTGGTGGTGCGGTGGAGCCGGGCGCGTAAGCGATACGAGCGTCAGGGCATCCTGGTCGAGGCGGAGGCGCTGGAGCGCGCCGAAAACGAGTGCCTCGCCGATGCGGAGGTGCGCGCCCGCCGCCGGGAGCGCGACGAGGCGCGACGGGCCAACGAGGACCTGCGTCTGCAAGCCGAATTCGGCGCCGCGATTCGCACGCTGTTCCCGAACTGCCCGGCCGGCCGGGCCGAGGCGATCGCCCGCCACGCGGCCACCCGCGGCAGCGGCAGGATCGGACGTAGCGCGGCCGGACGGGCGCTCGATCCCGAAGCGGTGAGGCTGGCCGTCGCGGCGTCGGTGCGGCATATCGACACTTCGTTCGACGAACTGCTGATGTCGGGTGTCGACCGGGAAACGGCGCGGCACCGGGTGGGTGAGCACGTCGAGGAAGTGCTGCGCGACTGGCGCGCGACCAGCCGCTGAACCTATTACTACCTAGGTACGACCCTGGTAGCATCTTAGGTTGTGAAGTTGAGCGTGAGCCTGTCCGATGACGACGTCGCGATCCTGGACGCATATGTGAAACGAGCGGGATTACCATCCCGCTCCGCCGGCCTGCAGCATGCGATCCGCGTGCTTCGCTACCCCACGCTCGAAGATGACTATGCCAACGCATGGCAAGAATGGTCGGCAGCCGGCGACACGGACGCGTGGGAGCAGACCGTCGGCGACGGAGTCGGTGATGCGCCGCGGTGAGATTTGGCAGGTCGATCTCGACCCCGCTCGAGGTAGCGAAGCGAACAACCAGCGCCCCGCCGTCGTCGTCAGCAACGACCGGGCCAACGCGACCGCCACGCGTCTTGGGCGCGGCGTCATCACCGTCGTGCCGGTGACGAGCAACATCGCCAAGGTCTATCCGTTTCAGGTGTTGTTGTCGGCCACCACTACTGGTCTCCAGGTCGACTGCAAGGCGCAGGCCGAGCAAATCAGATCGATTGCTACCGAGCGGTTGCTCCGGCCAATCGGCCGAGTTTCAGCCGCCGAACTTGCCCAGCTCGATGAGGCTTTGAAACTGCATCTCGACTTATGGTCGTAGCTCTCGCAGGTTCCGCGTCGGGGAGACCACTGGGCACGCGCCGCTGGACGGGCTCGGGTTATCGGCCGGGTCGCCGCCCGGGTCCGCCGCACCACCAGCCGTTAGCCGACGGGCAGCAGCAGCCGGGAGCGCCCGAAATGCACCGCGTGGGTAGCCGGCTTGAGCTGCCGTCCGGTGAGTATCGGTTCCGGGGTGCCGAGGTTTCGCGCATAGCGGGGAAACCAACTACCGGCGATCAGCACCCGGATGCGGGAGTCGGCGCGGAATCGGTGGGCGATGGCGTCCAGCTCGACGCGGACCAGCTCCGGCGCGTCACCAAGGCGCCGGTAGCCGTCGCTGACATTGCGGGACCGGCCCTTCGCGTCCACCTCGCTGACCCGAACGAACACGTCGACGTAGGGGTTGTCCGAGCTGTGCACCAGCTCGACGACGGGGTTTCCGTGCACGCAGAGGTCGTGGGTGAGGGGCGCCCCGGTGAAGCACAGCACATCGGCGCGCGTGGCCAGCCGGCTGTCGTCGCGGTAACCGCCGTTGGATGACAGTAGCGGACCACCGGTGGTCGGTGTCGGGTCGGCGGGGTGGTAGCGAAACGTCGCCGGTGGCGTGCCGGAAGCCGGAGCGCTCTCACCCAGGCGGCCACCGGGCTGCAGGTACCACGCCCGCTCGGTGGTCGCCGGAGGCCAGTCCGGCAGGTGCCGCCAGCCCTGGCCGGTGACGAAGACCCGCACCGGGCTGGGGCGCAGCGCCGGCGCCCGGCCGAGGTGGGCGTCCAACCAGTCCAACGATTCCCGAGCGCCGGTGGCCAGCCCCTTGGTGAGCATCTGGGTGTGTGTCCAGGGACCGACCGTCAGCGCGACGTGCACACCCCGGTCGCGCAGGTGCCGGTACTGCTGCAGCGTCTGCCGCAGGAAGATGTCCTGCCAGCCGCCGACGAGCAGCACCGGGACCTGGACGCGGTCCAACGCGGCGGGAAACCGCAGTCGGTCCCAGAACGGATCGTCGCGGTCGGTGTGTTCCACCCAGGATTCGAACCACGGCGCACCCGTGCCGAGCAGCGTCCGGGCCGACTCACCCAGCGGCAACGTGGCGGCCGTCCGCGCCACCCGTCGCGGCGCGGTGAGCTGGCGGATTCCGGCCCGGATGCGACCGGGGTCTTCCTGGTGGGAAACCAGATCGCTCCAGCCCAGGAAGTCGTTGACCGTAAACGATCCGGTGCCCCACACCGAGGCCCGGAAGTCGTGCGGCCCCACCGTGATCACGGCCGCGGCCAGCTCCGGGGGCGGATCGTGCAGCAACGCCCACTGGGTGAAACCCAGATAGGGCAGGCCGATGGTGCCGAACCGGCCGGTGAACCAGGGCTGTTCACGCAGCCACGCCACCGTATCGGCGCCGTCGGCGGCCTCGTTGACCATGGGCTCGAACACGCCACCGGACCCGAACGTCCCGCGCACGCTCTGCAGCACGACGTGATAACCGCGGGCGGCGTAAATCCGGGCAAACACCAGCGAAAACGGAAACCGGCGCCCGTATGGCCCACGCACCAGCAGGGTGCCGACGGGCTGCGACGTGGCGGGTGCGTAGTGGTCGGCCACCAGCTGGACGCCGTCGCGCATCGGGACTCGGACGTGACCGACGGTGTAGCGGGTGGTTGCGCGGGGCAGACCCAACAGTCCGCCCAGGGCCTGCCCACCGACTCGTCCGGTCAGGGCGCGCAGCTTGGGCCGCTCGGGCCGAGCGGAGGTGGTACTCACGACGCCCAGGGTAGGGACCTAAAACCTGTAGTAGGGGACGAGGTCGTTTGCCCGCTGCAGGTTGGTCGACGGGCAGTCCACGTCGGGCTCGGAGTAGACGGTCGAGTAGAACAGCGACTGCTGGATCACCCCGTAGCTGGTCTTGAAGGTCACCATGCAAGAGGAGTACCAGAAGCTGTTGTGATACGTCGGCTTCCGCACCCAGTACTGCGCGGCGCGGTGGCCGGCGATCGTGGTCTCGATCGCGTCGGGGGGCAGGGTCTGGGCGTAGGTGCGCCAGATGATCGGCTCGACGGCCATCTGATAGTTACCCGCGTCGAAGTGGCAGCGCAGCCCCTCCTCGGCTTCCGGTGGCGTGTAAGCCAATCCGAGCCGCTGGATGACGTCGAACGGGATGTCTCGGCACGGGTCAAACGGGCTGGGGTCGGTGGTCGCCACGATCGGGCTCTTCATCGTGGTGGACATGGGCGCCGCGGTCGATCGCAGCTGGACCGCGTCGCCGCCGGTCGGCGCTGGGGGGATGCCCTGCCAGCCCACCGTGCCCACCACCACCACCGCTGCCGTCAGCGCACCGAGCCCTCCGATCAGCCGCACCCTGGTGAACACGACACCCCCTGCCCTCGGCGGTCCCTTGCCGGGAGTGTACAAGTCGGCTCCGCGTCGTCACAGTCAAACGAGAACTTGTTCTAACCCGGGCCACCTTTGATGCGGTGAATTCTGCGGTAGTTCCCGCTGACGCATAATGTGATGCACTTCGATGGACGCAAGGAAGCAACGGGTGTTTCAGATCAGTCCGGAGCAGTGGATGCACTCGGCGGCGCAGGTGACCACGCAGGGTGAGGGTCTGGCCGTCGGACATTTGTCGTCGGACTATCGGATGCAGGCCGCCCAGTTCGGCTGGCAGGGCGCCTCGGCGATGGCGCTCAACGCCAAGATGGACGACTGGTTGGACGCGTCGAGGGCGCTGCTGACCAGGATCGGTGATCACGCATTCGGGCTGCAGGAGGCCGCTATCCAGCATGCGGCGGCGGAGGCGGAGCGGGCGCAGGCGCTCGCCCAGGTGGGTGTTTCCGCCGACGTCGTAGCTGGTCCGCGTGGGGTGTGATTCGTGCCACTGACCGTGGCCGATATCGATCGGTGGAACGCGCAAGCGGTCCGGGAGGTGTTTCACGCGGCCAGTGCCCGAGCGGAGGTGACGTTCGAGGCGTCGCGTCAGTTGGCCGCGCTGTCGATTTTTGCGAACTCGGGTGGCAAGACCGCTGAGGCGGCGGCACACCACAACGCGGGCATTCGCCGAGACCTCGACGCCCACGGCAACGAGGCGTTGGCGGTTGCCCGGGCGGCCGACAGGGCCGCCGACGGGATTGTGAAGGTTCAGTCCGAGCTGGCCGCACTACGCCATGCCGCCGCGGCCGCCGAGCTGACGATCGATGCGCTGATCAACCGGGTGGTGCCGATCCCCGGGCTGCGATCCACCGAGGCGCAGTGGGCGCGGACGCTGGCCAAGCAAACGGAGCTGCAGGCGGAGCTGGATGCGATTATGGCCGAGGCCAATGCCGTCGACGAGGAGCTGGCCTCAGCGGTCAATATGGCCGACGGTGACGCGCCCATCCCGGCCGATTCCGGCCCGCCGGTCGGTCCCGAGGGGCTGACCCCGACCCAGCTCGCCAGCGATGCCAACGAGGAGCGGCTGCGCGAGGAGCGCGCCCGCCTGCAGGCCCACCTCGAGCGGTTACAGGCGGAGTATGACCAACTGAGTGTGCGGGCCGCCCGTGACTACCACAACGGCATCCTCGACGGTGACGCGGTGGGCCGACTGGCAGCGCTTACCGACGAGCTGAGCGCCGCCAGGGGCCGGCTGGGTGAGCTCGATGCCGTCGACGAGGCGTTGAGCCGAGCACCCGAGACCTACCTGACCCAGCTGCAGATTCCCGAGGACCCAAATCAGCAGGTGCTGGCGGCCGTGGCCGTCGGTAATCCCGACACCGCCGCCAATGTGTCGGTGACGGTTCCCGGCGTCGGGTCCACCACCCGGGGCGCCCTGCCCGGCATGGTGACCGAAGCCCGCGACCTGCGGTCGGAGGTAATCCGGCAACTCAATGCTGCCGGCAAGCCCGCATCGGTTGCCACCATCGCCTGGATGGGCTACCACCCGCCCCCGAACCCACTCGACACCGGCAGTGCGGGCGATCTGTGGCAGACCATGACCGATGGGCAGGCACACGCGGGCGCGGCCGATCTGTCGCGGTATTTGCAGCAGGTGCGCGCCAATAACCCCAGTGGCCACCTGACCGTGTTGGGGCACTCGTATGGGTCGCTGACGGCGTCGCTGGCGTTGCAGGACCTCGATGCCCAGAGCGCCCATCCGGTCAACGACGTCGTGTTTTACGGCTCACCCGGCTTGGAGCTGTACAGCCCGGCGCAGCTCGGGCTCGATCACGGGCACGCTTATGTCATGCAGGCCCCCCACGACCTCATCACCAATCTGGTGGCGCCGTTGGCGCCGCTGCACGGATGGGGCCTGGACCCCTATCTGACCCCCGGGTTCACGGAGCTGTCGTCACAGGCGGGTTTTGATCCGGGCGGGATCTGGCGTGACGGAGTGTATGCCCACGGGGACTACCCGCGGTCCTTCCTCGATGCCGCCGGCCAGCCGCAGCTGCGGATGTCCGGCTATAACCTGGCGGCGATCGCCGCCGGGCTGCCCGACAACACGGTGGGCCCGCCGCTGCTTCCGCCAATTCTGGGTGGCGGCATGCCGGCAGCGCCCGGCCCAGCACTGAGAGGGGGACGTTGATGCGGTGGCCGACGGCGTGGCTGCTGGCTCTGGTGTGTGTGATGGCGACTGGGTGCGGACCCAGTGGCCACGGGACGCGGGCCGGCGAGGAGGGGCCGTTGAGCCCGGAGAAGGTCGCCGAGCTGGAGAACCCGTTGCGCGCCAAGCCCCCGCTGGAGGACGCCAAGGACCAGTACCGGGCGGCGGTGACCCAGCTGGCCAACGCCATCACGGCCCTGGTGCCCGGCCTGACGTGGCGAACGGATATGGACACCTGGACCGGCTGCGGTGGTGAGTATGAATGGACCAGGGCCAAAGCGGCGTATTTCATGATCGTTTTCAGTGGACCGATCCCCGACGACAAGTGGCTGCAGGCCGTGCAGATCGTCAAGGACGGTGTCGAACAGTTCGGTGCCACCGGCTTTGGGGTGATGAAGAACAAGCCGGCCGACCACGACGTGTACTTCGCCGGTCATGGCGGCGTCGAGTTCAAATGCTCGACCCAGAAGGCGGCGGTCCTCACCGCACAGTCGGACTGCCGGATCAGCCGGACCGACACCCCAAAACCCTCGCCGACCCCGTAGCAGTTGGGCTAGGTTGGCCGAGCAGACGCAAAAGCCCCCATTTCGGGCCCGAAATGGGGGCTTTTGCGTCTGCTCACGCCGTAGCGGTTGGTCGAACTGGCTGGATTTCGTTCCCACTTCGCCGGGTCGTTAGGGTGGTAAGTCGTGACCTGGAAAGGATCGGGGCAGGAGACCGTCGGCGCCGAGCCGACGCTGTGGGCGATCTCCGACCTGCACACCGGTCACCTCGGCAACAAACCCGTCGCCGAATCGCTGTACCCGTCCTCGCCGGACGACTGGCTGATCGTCGCCGGCGACGTCGCCGAACGCACCGACGAGATCCGCTGGTCGCTGGACCTGCTGCGGCGGCGGTTCGCGAAGGTGATCTGGGTGCCGGGCAACCACGAGCTGTGGACCACCAACCGCGACCCGATGCAGATCTTCGGCCGCGCACGCTATGACTATCTGGTCAACATGTGCGACGAGATGGGCGTCGTCACACCCGAGCATCCGTTCCCGGTATGGACCGAACGAGGCGGCCCGGCCACCATCGTGCCGATGTTTCTGCTCTACGACTACAGCTTTTTGCCGGAGGGGGCAAACAGCAAGGCCGAAGGTGTGGCCATCGCGAAGGAACGCAACGTCGTGGCCACCGACGAGTTCCTGCTCTCACCCGAGCCGTACCCCACCCGCGACGCCTGGTGCCACGAGCGGGTCGCGGCCACCCGGGCCCGTCTCGAACAGCTCGACTGGATGCAACCGACCGTGCTGGTCAACCACTTTCCGCTGCTGCGACAGCCCTGCGACGCGCTGTTCTACCCGGAATTCTCGCTGTGGTGCGGAACCACCAAGACCGCCGACTGGCACACCCGCTACAACGCCGTGTGTTCGGTCTACGGACACTTACACATTCCCCGCACCACCTGGTATGACGGTGTGCGGTTCGAGGAGGTGTCGGTGGGTTACCCGCGGGAGTGGCGCCGGCGCAAGCCCTACTCCTGGCTGCGGCAGGTGCTGCCGGATCCCCAATACGCGCCCGGCTACCTCAACGACTTCGGCGGTCACTTCGTGATCACGCCCGAGATGCGAACCCAGGCCGCCCAGTTCCGGGAACGATTGCGGCAACGGCAGTCTCGATGACGGTAGGCACGCTGGTGGCGTCGGTGTTGCCGGCGACCGTGTTCGAGGATTTGGCGTATGCCGAGTTGTACTCCGACCCACCCGGTCTCACCCCGCTGCCCGAGGAGGCGCCGTTGATCGCACGATCGGTTGCCAAGCGGCGCAACGAATTCATCACCGTGCGTCACTGCGCCCGCATCGCGCTGGACCAGCTCGGTGTGCCGCCGGCGCCGATCCTCAAGGGCGACAAGGGCGAACCGTGCTGGCCCGACGGCGTGGTCGGTAGCCTCACCCACTGCGCCGGTTACCGCGGCGCGGTTGTCGGACGCAGGGATGCGGTGCGTTCCGTGGGCATCGACGCCGAACCGCACGACGTGTTGCCCAATGGTGTGCTGGATGCGATCAGCCTGCCGGCCGAGCGCGCCGACATGCCCCGCACCATGCCAGCGGCGTTGCATTGGGATCGAATCCTGTTCTGCGCCAAGGAAGCAACGTACAAGGCGTGGTTTCCGCTGACCAAGAGGTGGCTGGGTTTCGAGGACGCGCACATCACGTTCGAAACCGATAGCACCGGCTGGACGGGTCGCTTCGTCTCCCGTATCCTCATCGACGGGTCCACCCTGTCGGGTCCGCCGCTGACAACGCTGCGGGGACGCTGGTCGGTTGAGCGCGGACTGGTGCTGACCGCGATCGTGCTATGAGCGCAACCGGCCCCGGAATCGTGGTTATCGACAAGCCCGCGGGAATGACCAGCCATGACGTGGTGGGGCGGTGCCGCCGCATCTTCGCCACCCGGCGGGTCGGCCACGCGGGCACCCTGGACCCGATGGCCACCGGGGTGTTGGTGATCGGCATCGAACGCGCCACCAAGATCCTCGGTCTGCTGACGGCGGCCCCCAAGTCGTATGCCGCCACCATCCGCTTGGGTCAGACCACTTCCACCGAGGACGCCGAAGGTCAAGTGCTGCAGTCGGTTCCGGCTAAGCACCTGACCATCGAGGCGATCGACGCCGCGATGGAGCGGCTGCGCGGTGAGATCCGGCAGGTGCCGTCGTCGGTCAGCGCGATCAAGGTCGGTGGCCGACGCGCCTATCGGTTGGCCCGCCAGGGGCGCTCCGTGCAATTGGAAGCCCGGCCGATCCGCATCGACCGGTTCGAGCTGCTGGCCGCACGCCGGCGCGACCAGCTCATCGATATCGATGTGGAGATCGACTGCTCCTCGGGAACCTACATCCGCGCGTTGGCACGCGACCTCGGCGACGCGCTTGGGGTGGGAGGCCATGTGACGGCGTTGCGGCGCACCCGCGTCGGCCGCTTCGAGCTGGACCAGGCGAGATCGCTCGACGATCTCGCGGAGCGCCCCGCGCTGAGCCTGAGCCTCGATGAGGCCTGCCTGCTGATGTTTGCGCGCCGCGACCTGACCGCCGCGGAGGCCAGCGCGGCCGCCAACGGCCGGTCCCTGCCGGCGGTCGGTATCGACGGCGTGTACGCGGCCTGTGACGCCGACGGCCGGGTTATCGCGCTGCTGCGTGACGAGGGTTCGCGGACCAGGTCGGTGGCGGTGCTCCGCCCGGCGACGATGCACCCCGGGTAGCGGGGTGAGGAGGAGCCGGGCGATTCGGTTGGAGCCTGGCCTCAATGTAGGGGGATGCGGTCCGGGACGGCAACGGTGGCACACTGGGCTACACGGCCTACGTCGCACGGCGATGGGCCGCTGTTCAATTCGGAAGGGGCTGTCAGCTGTTGCGGTCTGAGTGGTCGGTAGTTGTCAGTGGCGTGCTGTAGGAACAACAGTATGAATCTGGCGGTGTGGGCTGAGCGCAACGGTGTTGCGCGGGTGACTGCGTATCGCTGGTTTCATGCGGGGTTGTTGCCGGTGCCGGCGCGGAAGGCCGGGCGGCTGATTCTCGTGGACGACCAGCCGGCCGATAGATCCCGCCGGGCGCGGACGGCCGTGTATGCGCGAGTGTCGTCAGCGGATCAGAAGCCGGACCTGGATCGGCAGGTGGCGCGGGTGACCGCCTGGGCCACGACCGAGCAGATCGCGGTCGACAAGGTCGTGACCGAGGTCGGTTCGGCGCTGAACGGGCACCGCCGAAAGTTTCTTGCGCTGCTGCGTGACCCATCGGTGAAGCGGATCGTGGTGGAACACCGAGACCGGTTCTGCCGGTTCGGCTCTGAGTACGTCGAAGCGGCGCTGGCCGCCCAAGGCCGCGAGCTGGTCGTGGTCGACTCGGCCGAGGTTGATGACGACCTGGTACGGGACATGACCGAGATCTTGACCTCGATGTGCGCCCGGCTGTACGGCAAGCGCGCTGCGCAGAACCGGGCCAAGCGCGCATTGGCGGCCGCCGCCGAAGAGTCGGAGGCTGCCTGATGGCGAAATTCGAGATTCCTGAGGGCTGGATGGTTCAGGCTTTCCGGTTCACGCTCGATCCGACCGCCGAGCAGGCCCGCGCGTTGGCACGGCATTTCGGTGCCCGCCGCAAGGCCTACAACTGGACCGTCGCCACCCTGAAAGCCGATATCGACGCCTGGCAGGCGACCGGGATCCAGACGGCAAAGCCGTCGCTGCGGGTGTTGCGGAAGCGCTGGAACACCGTCAAGAACGACGTGTGCGTCAACATCGAGACCGGTGTTGTGTGGTGGCCGGAGTGCTCGAAGGAGGCCTACGCCGACGGTATTGACGGCGCGGTCGACGCGTACTGGAACTGGCAGAACTCGCGATCAGGCAAACGTGATGGCAAAAGGATGGGCTTTCCCCGGTTTAAGAAGAAGGGACGCGACCCAGACCGGGTGACGTTCACGACCGGAGCGATGCGCGTCGAGCCCGACCGGAGCCACCTCACGCTGCCGGTCATCGGGACCGTCCGCACCCACGAGAACACGCGCCGGGTTGAGCGGCTCATCGCCAAAGGCCGGTCGCGGGTGCTCGCGATCACGGTGCGCCGTAACGGGACCCGGATCGATGCGAGTGTGCGGGTCCTCGTGCAGCGCCCGCAGCAACCGAAGGTGACCGACCCCGGTTCACGGGTCGGCGTTGATGTCGGGGTGCGCCGCCTGGCCACGGTCGCCACCGCCGACGGCGCGGTGCTCGAACGAGTGCCGAATCCACGGCCACTCGACGCGGCACTCAACGAGCTACGGCATGTCTGCCGGGCACGGTCGCGCTGCACGAAAGGCTCACGTCGCTACCGTGAGCGCACCACCGAAATATCCCGGCTGCACCGCCGGGTCAACGATGTTCGCACCCACCACCTGCACTGTCTGACAACGCATTTGGCTAAGACCCACGGCCGCATCGTTGTCGAAGGCCTGGACGCGGCAGGGATGCTGCGGCAACAGGGCCTCTCGGGTGCCCGCGCTCGCCGGCGCGGACTCTCCGACGCGGCCCTGGGCACCCCGCGCCGCCACCTGTCCTACAAGACAGGCTGGTACGGGTCACAACTAGTGGTCGCTGACCGCTGGTTCCCATCGTCGAAAACCTGCCACGTCTGCGGGCATGTCCAAGAGATCGGATGGGCCGAGCACTGGCAATGCGATTCGTGCTCGGCATCGCATCAGCGTGATGACTGCGCAGCGATCAACCTCGCACGCTACGAGGACACCAGTAGCGTCGTCGGCCCAGTTGGGGCCGCCGTCAAGCGTGGAGCCGACCGTAAGACCCGGCCTGGCCGGGCTGGTGGCCGTGAAGCGCGGAAGGGAAGCAGCCGCAAGGCTGCCGAACAACCCCGAGACGGGGTGCAAGTCGCGTGACCACTAAAGATCACTCACTTGCAACGGCAACGATGCCTAACCAAGGGTCGTCGAACAAGGTTTACGTCATTGGCGTGGGCATGACGAAGTTCGAAAAGCCCGGGCGACGCGAAGGCTGGGACTACCCGGACATGGCCAGGGAGTCGGGCACCAAAGCGCTGCGCGACGCCGGCATCGACTACCGCGAAGTTGAACAGGGCTACGTCGGCTACGTCTACGGAGAATCGACGTCGGGTCAGCGGGCGCTCTACGAACTCGGCATGACGGGTATCCCCATCGTCAACGTCAACAACAACTGCTCGACCGGATCCACGGCGCTCTACCTCGGCGCGCAGGCCATCCGCGGCGGACTGGCCGATTGCGTGTTGGCGCTGGGCTTCGAGAAGATGCAGCCCGGAGCGCTGGGCGGTGGCGCCGACGACCGGGAGTCGCCGCTGGGCAGGCACGTCAAGGCGTTAGCCGAGATCGACGAGTTCGGCTTTCCGGTGGCGCCGTGGATGTTCGGGGCGGCCGGCCGCGAACACATGAAGAAATACGGCACCACCGCGGAGCATTTCGCGAAGATCGGCTACAAGAACCACAAGCACTCGGTCAACAACCCGTATGCACAGTTTCAGGACGAATACACCCTGGACGACATCTTGGCCTCAAAGATGATTTCCGACCCGCTGACCAAATTGCAGTGCTCTCCCACCTCCGACGGGTCGGCGGCGGTGGTGCTGGCCAGTGAGGATTACCTGGCCAACCACAACCTTGCCGGGCGGGCTGTGGAAATCGTCGGGCAGGCGATGACCACCGACTTCGCTTCCACCTTTGATGGCAGTGCCCGCAATATCATCGGCTACGACATGACTGTGCAAGCGGCACAACGGGTTTACCAGCAATCCGGACTCGGCCCGAAGGACTTCGGAGTGATCGAGCTGCACGACTGCTTCTCAGCCAACGAGCTACTGCTCTACGAGGCGCTCGGCCTGTGCGGGCCGGGCGAGGCGCCCGAGCTGATCGACGACAACCAGACCACCTACGGCGGACGCTGGGTCGTCAACCCATCCGGTGGGCTGATCTCCAAGGGCCATCCGCTGGGTGCGACGGGGTTGGCGCAGTGCGCGGAGCTGACCTGGCAGCTGCGCGGCACCGCCGAGGCGCGCCAGGTCGACAACGTGACCGCCGCGCTGCAACACAACATCGGGCTGGGCGGCGCCGCCGTGGTCACCGCATACCAACGGGCCGAACGTTGAGCCACGCGATCGGAGGGAGCACGCCATGTTCGAGTGGTCCGACACCGATCTAATGGTGCGCGACGCCGTTCGCCAGTTCATCGACAAGGAGATCCGCCCGCACCAAGACGCATTGGAAACCGGTGAACTGTCGCCGTATCCGATCGCGCGCAAGCTGTTCAGCCAGTTCGGTCTGGACGTGCTGCTTGCCGAGTCGGTCAACCAGATGCTGGATGGGGAGCGGGCTAAGCGGGAAAAGCGGGACAGCTCAGGCAGTTTCGGGCTGGCTGACCAGGCTTCGATGGTCGCGGTGCTGGTGTCCGAACTGGCCGGGGTCAGCATCGGATTGCTGAGCACGGTGGCCGTCAGCCTCGGGTTGGGCGCGGCGACGATCATGAGCCGCGGCACCCTGGCCCAACAGGAGCGCTGGGTGCCCACGCTGGTGACGCTGGAAAAGATCGCGGCCTGGGCCATTACCGAGCCAGACTCCGGCTCGGATGCGTTCGGCGGCATGAAGACTCACGTGACCCGCGACGGTGAAGACTACATCCTCAACGGGCACAAGACCTTCATCACCAACGGGCCGTACGCTGATGTCCTGGTGGTCTACGCCAAGCTCGCCGACGGTGAGCCCGCCTCAGATTGGCGTAACCGCCCGGTGCTGGTCTTTGTGCTCGATGCCGGCATGCCGGGCCTGACGCAGGGCAAGCCGTTCAAGAAGATGGGCATGATGTCTTCGCCGACCGGCGAGTTGTTCTTCGACAACGTGCGGCTGACCCCGGATCGCCTGCTTTGCGCCGAGGGGGACGGCCGCGACAGCGCCCGCGCCAATTTCGCCGTCGAACGCCTCGGCGTGGCGCTCATGTCGTTGGGCATCATCAACGAATGCCACCGGCTGTGTGTGGATTACGCAAAGACCCGCACGCTGTGGGGCCGTAACATCGGGCAGTTCCAACTGATCCAGTTGAAGTTGGCGAAAATGGAAGTTGCGCGGATCAACGTGCAGAACATGGTATTTCAGGCCATCGAGCGGCTCAAAGCCGGCAAACAGCTGACGCTGGCCGAGGCCTCGGCGATCAAGCTGTATTCCTCGGAGGCCGCCACCGATGTCGCGATGGAGGCCGTCCAGCTGTTCGGCGGCAACGGCTACATGGCCGAATATCGGGTGGAGCAGCTGGCTCGCGATGCCAAGTCGCTGATGATCTACGCCGGCAGCAACGAGGTCCAGGTAACCCACATCGCCAAGGGCCTGCTGGGCGAACCGGCTTCGCGAGCGTAACCGGACTGCGAAAATCCGTGCCGAAAATCGCAGCCACGTTACGCTCGCGGGCCAAAGCCGTCAGCTCACCACCCAGATTGCCTGGGCGGCCGGGCTCCCCAAGTCGACGGTGGCGCCGTCGGCCGAGTCGATTGCCACCGAGATCATGCCGGCGAACTCGCGCCGAGCCAGCACCCGCAGCCGCGAGTCCAGGCTGATCCCGATGCTGGCAAAGTATCGCAGCATCTGCGGGTCGGCATCGGAGATACGGGCCACCGTCCCTGTGTCGCCGTCGCGGCACGCCCACAGCTGACGAGCCGGTGGCGTGGGCACTTGCCCGTCGGCGCCCGGGATCGGGTCACCGTGCGGATCGCGCTGCGGGAACCCCAGCTTGGCGTCGATGCGGGCCATCAAGCGATCCGAGACCGCGTGCTCGAGCACCTCGGCCTCGTCGTGCACCTCGTCCCAGCGGTAGCCGAGCTCGTTGACCAGGAATGTCTCCAGTAGCCGGTGCCGGCGCACCATTGCCAGCGCGGCTCGTCGCCCCGAATCGGTCAACGTCACCGCGCCGTACTTCTCGTGGTCGACCAAGCCCTGCTCGGCGAGCTTGCGAATGGACTCCGAGGCCGTGCTGGCCGACACCCCGATCCTCTCGGCCAGCATCTTGGTGCTGACCTTGTCCTGCGACCACTCCTGGGCGGTCCAGATGACCTTCAGATAGTCCTGCGCAACCGCGCTAAGATCGCCAGGCTCCTCGTCAGCCCTCACAACCAGAGAGTCTAGATACCGGCGTGACGGCGCGCTCGGTGCGCAGTCGGGGAAATGGCCGCCAACTCGGTCTCGACCAAACCGTCATCCGACCTGACGCATCGTTTCGATCCAGGTTTTCCAACTGTCCTCGCCACGGGGCCGTACTCGGCTAGCCGGATAGTGCTGTGCCAGGCCGCCGGCCAAATCCAGCACGGCGTTGCGTGTCCTTCGCTTGAGAGAGCTGAAATCGACCGCCAAACCCGTGGCCAGATGCGGGTCGTAGGGAATCCGAAAGAAATCCGGAACGCGCTTCCTGAACTGGTTTTCGGCGGCCCCGCAATCCACAAGTGACCGGGTTTTCTGGATTGCGTTGAGAACAACCACAGTGTGCTGAAGCAACCGGCCAAAGCCATGCGCCCCCAGCCAGTCCAGAGTGACCAACGCTCCCTCGACACCGCGCACGTCTTCGGATGCCACCACAACCAGACCAGTGACGTCGTTGAGGATATTGCTGAACAATGGCCCGTTGACCGGTGTGCCGCAATCAAGCAGTATGACGTTGCAGTGGGTTTCCAGGATCTGCATGGCGGCCCCATAGTCCTCCGGGCCAAACTTGTATGTCGATCGCGGATCATTCTGGGCACCAAGCATTTCCAGCCGGTCTTTGTTCATCACCGTGTGCACACGCACGTCCGCGTAGCGCTTGGTGTGCTGCGATGACACGAAATGCTCGATGTTGGTCTGCGGGCCACCGCGCTCACTGAACCTTGCTGACAGGTCGCCCAGGTCGGCATCGACGTCCACAGCCATCACCCGATCGCCGCGCAGCCGGGCGACGGCGTTGCCCACCAGCACCGTCATCGTGGTCTTACCTACGCCGCCCTTGGCAGAGACGAACGCCAACTTATGGACATCGGCCAGTGGAGCGCAGATACGCTGAATCAGCTCGTCGGTTTGCTCGCGCTTGGCGCTCGGTTCGGGATTCACCCGCCCGAAAGTCATTTTGGTTACCGCTTTGCGCCAACCGTCCCCGGCCGGCGGGCGGCGGCGAGCCACCAGGAGATCCCGGCCGTCGTCGTAAGGATGTCGAAACTTCGGTTGGGGGCTACCAGCCTGTTCCGCGGTGGTGTTTGTCCTGGGGGCATCACCGGTGGTCGTGGCGCTAAGTGCCACTCTGGCGGCGTCGTCGTCACCCAGTTCGCGCAGGCACCACGCCCTAGTGAGGGTCACATCGGCAGTCACCCGCGGATTGGTTGTCGAGACTTGCTCAGCGAGCTCCAACGCGAACTGGAATTGGCCCAGACTCGCCGCAGCGGTCGAGGCCAGCGCGGCCACCGCGTCAGCCACCTCGTCACGGACATCGGTGGCCCCGCTCGGCGGAGAAATTTCGGTGACCTTCAAAAGGTTGGACCAGGAGCGAGTTTTGTGGAACAGCGTCGCCATGACGAACTGGCGGTATTGGGCGGCGCCGGTGTCCTCCGTGATGACCGGGTCGTCCAGCGTTGCTGCCGCTTCATCGTGGCGGTCGGCGATGATTAGAGCGCTGGCGTACGCGAGCCCGATCGTGGCGCGCGACCACACCCGCAACCCCAGATACATCGGGGCCATGACCACGGCGGACAATTCGCCGTCCGTGAGGCCGACGCGGCGGGTTTCGCTGTACAGTGCTTCGGAGTGTTGATGGGCACCGGCCAAGGTATCAAGATGATGGTCGCCGCAGGCCAGAAGCCCCAACCAGCCATCGGACATGTCCGGGTTTTCGACTGTGAGGCGGCCAAAGGCCGCTCGGGCATTGGCCAGGTCTCCGGACTGGTAGCTCTTCACCGCGGCATCGAACATGCTGCGGCATTCTCTAAACGTACTCATCAGACCCACTCCCTGATCACCTGATCAATGGTCGGCGTAAAGCTTGAGACCAATCGTTCGGTATGCGCGCGCCAATTCTCTGGGACCGGCCACGGTGCCGCCGGCGTTCCCGGACGTGCTGCGCCAGGTGTCCGGCGGCCGCGTGCATGGTGTTCCCGGATCGGCCGCTGGCCAGAGCCCACCGGTGAATCTGGCGCCTGGCCGACCACCGTGCGCCGTAGGCTTGCGATCGTGCAGCGCTGGCGTGGCCAGGACGAGATCCCGACGGATTGGGGCAGATGCGTGCTCACCATCGGGGTATTTGACGGCGTGCACCGCGGGCACGCCGAACTGATCGCGCACGCGGTCAAGGCCGGCCGCGCTCGCGGTGTACCGGCCGTGCTGATGACGTTCGACCCGCACCCGATGGAGGTGGTCTATCCAGGCAGTCACCCGGCGCAGCTGACCACCCTGACCCGACGCGCGGAGCTCGTTCAAGACTTGGGCATCGAAGTGTTCCTGGTGATGCCGTTCACCACCGATTTCATGAAGCTCACGCCGGATCGCTTCATCCATGAGCTGCTCGTCGAGCACCTACATGTGGTGGAGGTCGTCGTCGGCGAGAACTTCACCTTCGGCAAAAAGGCCGCCGGCAATGTCGACACGCTGCGTCGGGCTGGCGAGCGGTTCGGGTTCGCGGTGGAATCGATGTCGTTGGTGTCCGAGCACCACAGCAACGAGACCGTGACGTTCTCCTCCACCTACATCCGGTCCTGCGTGGACGCCGGCGACATGGTGGCGGCCATGGAAGCTCTGGGCCGACCGCACCGCGTGGAGGGGGTTGTGGTACGCGGTGAGGGGCGGGGCGCGGAGCTGGGCTTTCCCACCGCGAACGTGGCGCCGCCGATGTATTCGGCGATTCCGGCCGACGGCGTGTACGCCGCTTGGTTCACGGTGCTCGGGCATGGGCCGGTGACCGGCACGGTCGTCCCGGGTGAGCGCTACCAGGCCGCGGTGTCGGTCGGGACCAATCCCACCTTCTCCGGACGCACCCGCACCGTCGAAGCGTTCGTGCTGGACACCACCGCTGACCTCTACGGTCAACATGTGGCCTTGGACTTCGTCGGGCGTATCCGCGGCCAGAAGAAGTTCGAATCGGTGCGCCAGCTGGTCGCTGCGATGGGTGCCGATACCGAGCGGGCACGTGACCTGTTGTCTACGGGTTGACGGTTCTTGCGGTCGTGACCCCCGGCTGGCACCTGCGGCGTTTGTGTTTGGCGGTCAACCCGCTGCTAGACTGTCCAACGACATCGGTGCGTGCTGCGGTTCGCGGTGGCCGTGCCCTGATATCCATGATCGCGAACCCATTGATGGAGACATTTCGTGGCGCTGACAGCCGAGCAAAAAAAGGAGATTCTGCGCTCCTACGGCCTGCATGAGACCGATACCGGATCCCCGGAAGCACAGATCGCGTTGCTGACCAAACGCATCGCCGACCTCACCGAGCATCTCAAGGTGCACAAGCACGACCATCATTCGCGGCGAGGACTGCTGTTGCTGGTGGGCCGGCGGCGCCGGCTGATCAAGTACATTTCCCAGATCGATGTGGAGCGTTATCGTTCACTCATCGAGCGGCTGGGCCTGCGTCGCTGACCCGCGGCGTCGATGCGCGCCTGGCTCGCGGCCGCGACCACGGCCTTGTTCGTCGTGGCGACGGGGTGTTCGTCAGCGACCAACGTCGCCGAACTCAAGGTGGGGGACTGCGTCAAACTCGCCGGCACGCCCGACCGGCCGCAGGCCACTAAGGCGGAGTGCGGGAGCCCGGCGTCCAACTTCAAGGTCGTTGCCGTCGTGCAGGAGGACCACGCGGAATGCCCGGCGGACGTCGACTCCACCTATTCGATGCGCAATGCGTTCAACGGCTCAACCAACACCATTTGCCTGGACATCGATTGGGTGATTGGCGGTTGTATGAGCGTCGACCCTACCCACAACACCGACCCGTTCCGGGTGGACTGCGACGACGCCTCGGTGCCGCACCGGCAGCGGGCCACCCAGATCCTGAAAGACCTCGACTCTCCCGTCAGCGTCGACCAGTGCGCCAGCGGCGTGGGCTACGTCTACACTCAGCGACGGTTCGCGGTGTGCGTCGAGGATGTCACCGGCGGCCCGCGGAGCTGAGGCGGGGTAGCTCGGCAAAGCGAGTTCTACGCAAATGCCGCCGGTCGCCCGTGTAGAGTGAGAACGTTCTGGGCCGGTTCGGCCCAGCAAATGGTGCGGTACGCGCAGAACCGCGTGTGCCGTTCCAGCGAGTCACTATGCATATCCAAGGGAGCACCCCCGGCCTGTATCGGGCGGTCCTCGGTAGTGGCTGCCGGGCTCTCCGGATCTGGGGCAGGTCGGCCGCTTCGATCGATGGCCGTAGCCGCATTCAGACCTTTTCTCCTGGGAAGCTCTCGGGGTTCGGCGAACCCGCTGGATTGCGCGTGACGACGCGAAACAGCTCAATAATCCAGAGAGGCCGCACGGACGTCATGTCTGCCGCTGAAATTGACGAAGGCGTGTTCGAGACGACCGCCACCATCGACAACGGGAGCTTTGGCACCCGGACCATCCGCTTCGAGACCGGCCGATTGGCCTTGCAGGCCGCCGGCGCGGTGGTCGCCTACCTCGACGACGACAACATGCTGCTGTCGGCGACCACCGCCAGCAAGAACCCCAAAGAACACTTCGACTTCTTCCCCCTCACGGTCGACGTCGAGGAGCGCATGTATGCGGCCGGCCGCATCCCCGGTTCGTTCTTCCGTCGCGAGGGCCGACCCTCCACCGACGCGATCCTGACCTGCCGGCTCATCGACCGCCCGCTGCGCCCGTCGTTTGTCGACGGGCTGCGCAACGAGATCCAAATCGTGGTGACGATTCTCAGCCTGGATCCGGGCGATCTCTACGACGTATTGGCGATCAACGCGGCGTCGGCGTCCACCCAGCTGGGCGGTCTGCCGTTCTCCGGGCCCATCGGCGGTGTGCGGGTGGCGCTCATCGACGGCACCTGGGTCGGCTTCCCCACCGTCGACCAGATCGAGCGCGCCGTGTTCGACATGGTCGTGGCCGGCCGGATCGTCGAGGGTGATGTTGCCATCATGATGGTCGAAGCCGAGGCCACCGAAAACGTCGTCGAGCTCGTCGAAGGTGGTGCCCAAGCGCCGACGGAAAGCGTGGTGGCCGCGGGCCTGGAGGCGGCCAAGCCGTTTATCGCCGCGCTGTGCACCGCGCAGCAGGAGCTTGCCGATGCCGCTGGAAAGTCGGGCAAACCGACCGTCGACTTCCCGGTGTTCCCTGACTACGGCGAAGACGTGTACTACTCGGTGTCCTCGGTGGCCACCGACGAGTTGGCCGCCGCGTTGACCATCGGCGGTAAAGCCGAGCGCGACCAGCGCATCGACGAAATCAAGACCCAGGTTGTGCAGCGGCTCGCCGACACCTACGAGGGTCGCGAAAAGGAGGTCGGCGCCGCGTTGCGTGCCCTGACCAAAAAGCTGGTTCGGCAGCGCATCCTCACCGACCATTTCCGTATCGACGGCCGCGGCATCACCGACATTCGCGCATTGTCGGCCGAGGTGGCCGTGGTTCCGCGCGCGCACGGCAGCGCGCTGTTCGAACGCGGCGAAACCCAGATCCTGGGTGTGACCACACTCGACATGATCAAGATGGCCCAGCAGATCGACTCGTTGGGGCCGGAGACATCGAAGCGGTACATGCACCACTACAACTTCCCGCCGTTCTCCACCGGCGAGACCGGTCGGGTCGGTTCGCCCAAGCGGCGTGAGATCGGGCACGGCGCACTGGCCGAGCGGGCCCTGGTGCCGGTGTTGCCGAGCGTCGAGGAATTCCCGTATGCCATTCGCCAGGTGTCGGAGGCTCTGGGCTCCAACGGGTCGACCTCGATGGGGTCGGTGTGCGCGTCGACGCTGGCGCTGCTCAACGCCGGGGTGCCGCTCAAGGCGCCGGTGGCCGGCATCGCGATGGGCCTGGTCTCCGACGACATTCAAGTAGAAGGGGCGGTCGACGGCGTTGTGGAGCGTCGCTTCGTCACCCTCACCGACATCCTCGGCGCCGAAGACGCGTTCGGTGACATGGACTTCAAGGTCGCCGGGACCAAGGACTTCGTCACCGCGCTGCAGCTGGACACCAAGCTCGACGGGATCCCTTCGCAGGTGCTTGCCGGAGCACTCGAGCAGGCCAAGGACGCCCGCCTCACGATCTTGGAGGTGATGGCTGAGGCCATCGATAGACCCGACGAAATGAGTCCCTACGCCCCGCGGGTGACCACCATCAAGGTTCCGGTGGACAAGATCGGGGAGGTCATCGGACCCAAGGGCAAGGTCATCAACGCCATCACCGAGGAGACCGGCGCGCAGATCTCCATCGAAGACGACGGCACCGTGTTCGTCGGCGCCACCGACGGGCCATCGGCACAGGCCGCGATCGACAAGATCAACGCCATCGCCAACCCGCAGCTGCCGACGGTGGGCGAACGGTTCCTCGGAACCGTGGTCAAGACCACCGATTTCGGTGCCTTTGTATCGTTGCTGCCTGGCCGCGACGGTCTGGTGCACATTTCCAAACTCGGCAAGGGCAAGCGCATCGCGAAGGTCGAGGACGTTGTCAATGTCGGTGACAAGCTGCGGGTGGAGATCGCCGACATCGACAAACGGGGCAAGATCTCCCTGATCCTGGTCGCCGACGAGGACAGCACCGCCGCCGCTACCGATGCCGCGACGGTCACCAGCTGACCCCGCGGCGGCGCTGGCGCCGCGGCGCACCACCCTGCCGGGCGGGCTGCGAGTGGTCACCGAATTCCTGCCCGCGGTGCACTCCGCGTCGGTCGGGGTGTGGGTCGGCGTCGGATCGCGCGACGAAGGCGCCACGGTGGCCGGGGCGGCGCACTTCCTTGAGCATTTGCTGTTCAAGTCGACGCCCACCCGCTCTGCCGTGGACATTGCGCAGGCGATGGACGCGGTGGGCGGGGAACTGAACGCATTCACCGCCAAGGAGCACACCTGCTACTACGCCCACGTGCTCGGCAGCGACTTGCCGTTGGCCGTCGACCTGGTCGCCGATGTGGTGCTCAACGGCCGCTGTGCCGCCGACGATGTCGAGGTGGAACGTGACGTCGTCCTCGAGGAGATCGCGATGCGCGACGACGACCCCGAGGACGCCTTGGCGGACATGTTCCTGGCGGCGTTGTTCGGCGACCACCCGGTCGGTCGCCCGGTGATCGGCAGCGCGCAATCCGTGTCGGTGATGACGCGGGCTCAACTGCAATCGTTTCACCTGCGGCGCTATACCCCGGAGCGGATGGTCGTCGCGGCCGCCGGCAATGTGGATCACGACGGGCTGGTTGCGTTGGTCCGCGAGCACTTCGGGTCCCGGTTGGTCCGGGGGAGACGGCCAGTTGCGCCGCGCAAGGGTACCGGCCGGGTCAACGGCAGCCCCCGGTTGACACTGGTTAGCCGCGACGCCGAACAGACGCATGTGTCGCTGGGCATCCGCACACCCGGGCGCGGCTGGGAGCATCGTTGGGCACTGTCGGTGCTGCACACCGCGCTGGGCGGTGGCTTGAGTTCCCGGCTGTTCCAGGAGGTCCGCGAGACCCGCGGGCTGGCCTACTCGGTCTACTCCGCGCTGGATCTCTTCGCCGACAGCGGCGCGCTTTCGGTGTACGCGGCCTGCCTGCCCGAACGCTTCGCCGACGTGATGCGGGTGACCGCCGATGTGCTGGAAAGCGTGGCACGCGACGGCATCACCGAGGCGGAATGCGGCATCGCCAAGGGATCGCTGCGGGGTGGGCTGGTGCTAGGGCTGGAGGATTCCAGCTCCCGGATGAGCCGGCTCGGCCGCAGCGAGTTGAACTACGGCAAGCACCGCAGCATCGAACACACCTTGCGGCAAATCGAGCAGGTCACCGTGGAGGAGGTCAACGCGGTGGCCCGCCACCTGCTGAGCAGGCGCTACGGTGCTGCCGTTCTTGGCCCACACGGATCGAAACGATCACTGCCGCAACAACTTCGAGCGATGGTAGGGTAGCTCAAATGTCCGCTTCCTCACTCGCGCCGTGCCGGCGCTCGCCGTCGGCGAATTAGCCCGATGGTGTTGGGCTTCTGGGACATCGCGGTGCCGATCGTCGGCGCCCCGATGGCCGGCGGCCCGAGCACCCCGGCGTTGGCCGCGGCGGTGTCCAACGCTGGCGGGCTTGGTTTCGTCGCCGGCGGCTATCTGAGCGCGGACCGGCTCGCCGACGATATCGCCGCTGCGCGCGCCGCCACTACCGGTCCTATCGGAGCCAATCTGTTTGTGCCCCAACCCAGCGTCGCCGACTGGGCGCAGCTGGAGTATTACGCGGACGAGCTCGAAGAGGTCGCCGAGTACTACCACACCGAGGTGGGCCAGCCCGTCTATGGTGACGACGACGACTGGGTGCGCAAACTCGAGGTGGTAGCCGATGTTCGTCCGGAGGTGGTGTCGTTCACCTTCGGCGCGCCGCCGCCGGATGTCGTGCAGCGGTTGAGCGCGCTGGGACTGTTGGTCTCGATCACCGTGACGTCGGTCTACGAGGCCGGTGTGGCCATTGCCGCGGGCGCGGACAGCCTGGTGGTCCAGGGCCCGGCTGCCGGCGGGCACCGCGGAACGTTCGCGCCGGACATGGAACCCGGTACGGAGTCGCTGCACCAACTCCTCGATCGGATTGGCAGCGCCCATGATGTGCCGCTGGTTGCAGCCGGTGGCCTGGGCACGGCTGAGGACGTGGCCGCCGTGCTGCGCCGCGGAGCGATCGCCGCGCAGGTTGGTACCGCATTGCTGCTGGCCGACGAAGCCGGTACCAATGCCGCACACCGTGCCGCGCTGAAGAATCCAGAGTTCGATGCCACCCTGGTCACTCGGGCGTTCTCGGGTAGGTATGCGCGCGGTCTGGCCAACAACTTCACTCGCCTGCTCGACCACGTGGCGCCGCTGGGTTATCCGGAGGTCCACCAGATGACGAAGCCGATACGGGCGGCGGCGGTGCAGGCGGACGACCCGCACGGAACAAACCTTTGGGCGGGATCGGCGCACCGGAAGACCCGGCCGGGACCCGCGGCCGACATCATCGCTTCCCTTACTCCCGACGTGTGCTCGGCGTAACGAGCGGCCGAGAGTCAGGCCAGCACGCTGGCGGGCTCGGTGAACGGCACCCCCAGGTCGGTGGCCACCCGTTCGGACAGTAACGCCCCTTCGTGCGTCGAAAGACCTTTGGCTAGTGCCGGATTCGACCGGCACGCCGCCCGCCAGCCATGGTCGGCAAGCTCGAGCACATACGGCATCGTCGCGTTGGTCAGCGCGTAGGTCGACGTCTTCGGCACCGAGGCGGGCATGTTCGCCACGCAGTAAAACAGCGTGTCGTGCACGGCGAACGTCGGGTGGTCGTAGGTGGTCGGTCGTGAGCCTTCGAAACAGCCGCCCTGGTCGATGGCTATATCCACCAGTACCGCACCTGGTTTCATATGCGCGACAAGTGAATTCGAGACTAATTTGGGTGCCTTGGCGCCTGGCACCAGGACGGCCCCAATCACCAGGTCGGCACGTTTGACGGCACCCTCGAGCTCGTAGGCCGATGAGTAGCGAGTGTGGATCCGGCCGCAGAACTCGGCGTCGAGTTGCCGAAGTTTGTCGATGTTGATGTCTAGAACCGTAACGGTCGCGCCCATGCCGTTGGCGATGCGGGCTGCGTTGTAGCCGGCGGTGCCGGCGCCGATCACCACGACGTCGGCCGGTTCGACGCCGGGCACCCCGCCCATCAGCACACCGCGGCCCCCTTGGGTTCGCATCAGGTGGTAAGCGCCAACCTGGGCGGCGAGTCGACCGGCGACTTCGCTCATCGGGGCAAGCAGGGGTAGTGCGCCGTCGGCGGTCTGGACGGTCTCGTAGGCAATTGACGTGGTGCCGGAATCCAACAACGCATCGGTGCAAGCACGTGACGCGGCCAAATGCAAGAACGTGAACAAGATCTGCCCGTGTCGCAGGCGGCCGTATTCCGCCGCTATCGGTTCTTTGACCTTGAGCAATAAATCAGCGTCGGCCCACACCTGGTCGGCGGTGCCGACCAGTTGCGCGCCTGCCGCCTTGAAATCCGCGTCGGTGATAGCCGAGCCCTCTCCGGCACCTGCCTGGATGAGCACCTCATGGCCACGACGGGTTAGTTCCGCGACGCCGGCCGGGGTGATGGCCACCCGGAATTCGTTGTTTTTGGTCTCGGTCGGAATACCGACGCGCATGATTACCCCTCTCGATACTGTACGCTTCAGTGTGAAGAAAGTTCGATTAATCTGCAAGATTGCTGATGATAATTCTTTTTCGAGGCCATATGCGTGATAATTCAACGGAACACAAGACTCGCCGGGCTGCCTCGTCGAAGGATGTTCGACCCGCTGAACTTGATGAGGTGGACCGCAGAATCCTGAGCTTGCTGCATGGCGATGCCAGAATGCCCAACAACGCGTTAGCGGACACTGTCGGGATAGCGCCGTCGACGTGTCACGGCCGGGTTCGGCGGTTGGTGGACCTCGGCGTGATCCGGGGGTTCTACACCGACATCGACCCGGTCGCGGTGGGTTTGCCGTTGCAGGCGATGATCTCGGTCAACTTGCAGTCGTCCGCTCGCGGGAAAATCCGCAGCTTCATCCAGCAGATCCGCCGCAAACGGCAGGTGATGGATGTCTACTTTCTGGCCGGCGCCGACGATTTCATCTTGCACGTCGCCGCTCGCGACACCGAGGACCTGCGTTCGTTCGTGGTCGAAAACCTCAATGCCGACGCCGACGTCGCAGGTACCCAGACGTCCCTGATCTTCGAGCATCTGCGCGGGGCGGCGCCCATCTAGAGCGGCCCGCCCAGCGGGCTATGATCGCGGGATGCCAGACCCTGATGGGCCTTCTGTGACGGTCACCGTTGAGATCGACGCCAATCCCGACCTGGTATACGGGCTGATCACTGATCTGCCGACACTGGCCTCGCTGGCCGAGGAAGTGGTGGCGATGCAGTTGCGCAAAGGCGACGATGTTCGCAAGGGAGCGGTGTTTGTCGGTCGCAACGAAAACGGTGGACGGCGCTGGACCACGACGTGCACCGTTACCGACGCCGATCCCGGTCGGGTTTTCGCTTTCGATGTACGGTCCGGCATTATTCCGATTTCACGCTGGCAATATGGCATCGTCGCTACCGAACACGGCTGTCGGGTTACGGAGAGCACCTGGGACCGGCGGCCCAGCTGGTTCCGCGCAGTTGCCCGGATGGCCACCGGCGTCAAGGATCGGGCGAGCGTAAACACCGAGCACATTCGACGCACCCTGCAGCGTCTCAAGGACCGAGCTGAGGCCGGGTAGCGAAAGTGCTGGCGGGACACTGATGGCGAGTCGCGTGCCGTAGCAAGTGCGTTGCTGCGCAATGGCATTACTGATGCCACCAGTTGCGAGTAGGCCGACGAGGGCGAGGCGACGAATTCGACACGGTGAAGCCGACATCGTCGGCTGCCGAGGCGCGGTGAACGTCGAGGTGCATTCGGCGCCAGGCTGGCGAGCAGGTTCTTCACCCCTCGGGTACGCGCAACTATACTTGCCAACACGTGATGTCTACTGGGGCGACATGTCGGGCATTTATGTAAACGCCGTGGCTACGTTTTCTGAGGGGGCAGCAATGGTCAGCGTCGATGACCGGGCGACGGGTCCGCACTCGTCAGAGTCGCGCGCCGCCGACCACGAACGTCTCGTCCTCGAGCCGCGAGATGTCGAATTCGACTGGACAAACCTGCCATTTCACTATGTGCCCAACGAGCCGATGGCCACCCACGTTCTCAACGTTCTGCATATGCTGCTGCCGGCCGGCGAGGAGTTCTTCGTCAGGGTCTTCAAGAAGACGCTGCCGCTGATCAAGGACGATCAACTGAGGCTGGACGTGCAAGGATTCATCGGTCAGGAGGCGATGCATTCCCAGGCGCACTCCGGCGTGGTTGACCACTTCGATGCCCAGGGTGTCGACGTGACAGCGTTTACCAACCAGATCAGGTGGCTGTTCGAAAAGCTGCTGGGGGAGAGTCCTCGGCGGAGCCCGCGACGACAGTACAGCTGGTTGCTAGAGCAGGTTTCGTTCATCGCGGCAATTGAGCACTACACCGCCGTCATGGGCGAGTGGATCCTGAATTCCCCGCAGCTCGATGCCGTCGGTGCAGACCCCGTGATGCTGGACATGCTGCGGTGGCACGGTGCAGAAGAAGTCGAGCACAAAGCCGTGGCCTTCGACACCATGAAGCACTTGCGCGCCGGTTACTGGCGGCAGGTGCGTGCCCAGCTGACCGTTACCCCGGTGATGTTGCTGCTGTGGATTCGCGGAGTGCGGTTCATGTATTCGGTGGATCCGTACCTGCCACCGGGGACAAAGCCGCGCTGGCGGGACTATTTCAAGGCCGCACGCCGTGGTTTGGTGCCCGGGCTGCCGCGGCTGCTTCGGGTCGTGGGGCACTACTACAAGCCGGGTTTTCACCCGTCCCAGCTGGGCGGGCTGGGGGCGGCCGTGGACTACCTGGCCGTCTCGCCCGCCGCGCGAGCGTCGCACTGATCGGTGACGATCCGTAGGAATGGCGGAGCGCACCGTGCCAGAGACCAGCTGGGCCAGTAGGCCCGCCGACCTTTACGGTCGCCGCAGCCGGGACCGCTTCTTCACAGCGCTGTGGGGTGTACGAGCGTTATTGGGAGGATTGGGCGCGGCCTCGCGGTGGGAACCGTCGCGGGTGCAGCCGGTGCGGCGCACGAATCCCGCGGTGGTTACCAAGCGCGAGCTGGTCGCTCCCGACGTGGTGGCGTTGACGTTGGCTGACCCCGGTGGCGGATTGCTCCCGGCCTGGTCGCCCGGTGGGCACATCGACGTGCAGCTGCCCTCGGGGCGGCGCCGACAGTACTCGTTGTGCGGTGTGCCCGGACGGCGTACGGACTACCGGATCGCCATTCGCAGAATCGCGGACGGCGGCGGCGGTTCGATCGAGATGCACGAGGCCTTCGACGTAGGTGACACGTGCGAGTTCGAAGGTCCCCGCAACGCCTTCCATCTCGGTCTGGCCGAGCGTGACGTGCTTTTCGTGATCGGCGGTATCGGGGTGACGCCCATCCTGCCGATGATCCGGGCCGCCGAACAGCGCGGAATCGACTGGCGCGCAATCTATGCCGGTCGCGGTCGGGAGTACATGCCGTTCCTGGACGAGGTAGTGGCGGTGGCACCCGGCCGGGTCACGGTGTGGGCCGACGACGAGCACGGTCGTTTTGCGTCTGTCGATGAACTGTTGGCCGGCGCAGGGCCGACGACGGCCGTTTACGTGTGCGGGCCGCCCGGGATGTTAGAAGCGGTGCGCGTGGCCCGCAATCAACACGCCGACGCGCCGCTGCATTACGAGCGATTCAGCCCGCCGCCGGTTGTCGACGGAGTTCCGTTCGAGCTGGAGCTCGCACGGTCGAGGCGAGTGCTCCGAGTTCCGGCGAACCGGTCGGCGCTGGACGTCATGCTCGACTGGGACCCGACGACGGCATACTCCTGCCAGCAGGGCTTCTGCGGGACCTGCAAGGTGAGAGTCCTTGCCGGGCAGGTCGACCGCCGCGGCCGCATCATCGAAGGCGATAACGAGATGCTGGTCTGTGTGTCGCGGGCCGTGAGCGGTCGGGTGGTTATCGACGCCTGATGCTTACCCGGGCGGGGCGGATCGATAAAGCCGGTAGCCCACATGGGGCACGTTCACACCTGACAGTGGTTTCCACGTGAAAGTGCGGCCGTCAATGTGAAAGTCCTTCTTCTCGTAGAAGCCGCGTGCCTTGCTGTTCTTCTCGGCGCACCACAAAATCATGTCGGCTGTGAACCGCCCCGGTGAGTCCGGAGACTCTCTGATCTGAGACCTCAGCCGGCGGCTGGTCTCTGGCGTTGAGCGTAGTAGGCAGCCTCGAGTTCGACCGGCGGGACGTCGCCGCAGTACTGGTAGAGGCGGCGATGGTTGAACCAGTCGACCCAGCGCGCGGTGGCCAACTCGACATCCTCGATGGACCGCCAGGGCTTGCCGGGTTTGATCAGCTCGGTCTTGTATAGGCCGTTGATCGTCTCGGCTAGTGCATTGTCATAGGAGCTTCCGACCGCTCCGACCGACGGTTGGATGCCTGCCTCGGCGAGCCGCTCGCTGAACCGGATCGATGTGTACTGAGATCCCCTATCCGTATGGTGGATAACGTCTTTCAGGTCGAGTACGCCTTCTTGTTGGCGGGTCCAGATGGCTTGCTCGATCGCGTCGAGGACCATGGAGGTGGCCATCGTGGAAGCGACCCGCCAGCCCAGGATCCTGCGAGCGTAGGCGTCGGTGACAAAGGCCACGTAGGCGAACCCTGCCCAGGTCGACACATAGGTGAGGTCTGCTACCCACAGCCGGTTAGGTGCTGGTGGTCCGAAGCGGCGCTGGACGAGATCGGCGGGACGGGCTGTGGCCGGATCAGCGATCGTGGTCCTGCGGGCTTTGCCGCGGGTGGTCCCGGACAGGCCGAGTTTGGTCATCAGCCGTTCGACGGTGCATCTGGCCACCTCGATGCCCTCACGGTTCAGGGTTAGCCACACTTTGCGGGCACCGTAAACACCGTAGTTGGCGGCGTGGACGCGGCTGATGTGCTCCTTGAGTTCGCCATCGCGCAGCTCGCGGCGGCTGGGCTCCCGGTTGATGTGGTCGTAGTAGGTCGATGGGGCGATCGGCACACCCAGCTCGGTCAGCTGTGTGCAGATCGACTCGACACCCCACCGCAA

Protein sequences of DBSCAN-SWA_1

>NC_018078|1292015:1331492|1292015_1293276_+|WP_087902221.1|transposase|DBSCAN-SWA
MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_018078|1292015:1331492|1303031_1303262_+|WP_003901465.1|DBSCAN-SWA
MKLSVSLSDDDVAILDAYVKRAGLPSRSAGLQHAIRVLRYPTLEDDYANAWQEWSAAGDTDAWEQTVGDGVGDAPR
>NC_018078|1292015:1331492|1308857_1309832_+|WP_003414151.1|DBSCAN-SWA
MTWKGSGQETVGAEPTLWAISDLHTGHLGNKPVAESLYPSSPDDWLIVAGDVAERTDEIRWSLDLLRRRFAKVIWVPGNHELWTTNRDPMQIFGRARYDYLVNMCDEMGVVTPEHPFPVWTERGGPATIVPMFLLYDYSFLPEGANSKAEGVAIAKERNVVATDEFLLSPEPYPTRDAWCHERVAATRARLEQLDWMQPTVLVNHFPLLRQPCDALFYPEFSLWCGTTKTADWHTRYNAVCSVYGHLHIPRTTWYDGVRFEEVSVGYPREWRRRKPYSWLRQVLPDPQYAPGYLNDFGGHFVITPEMRTQAAQFRERLRQRQSR
>NC_018078|1292015:1331492|1329465_1330395_+|WP_003414104.1|DBSCAN-SWA
MRRTNPAVVTKRELVAPDVVALTLADPGGGLLPAWSPGGHIDVQLPSGRRRQYSLCGVPGRRTDYRIAIRRIADGGGGSIEMHEAFDVGDTCEFEGPRNAFHLGLAERDVLFVIGGIGVTPILPMIRAAEQRGIDWRAIYAGRGREYMPFLDEVVAVAPGRVTVWADDEHGRFASVDELLAGAGPTTAVYVCGPPGMLEAVRVARNQHADAPLHYERFSPPPVVDGVPFELELARSRRVLRVPANRSALDVMLDWDPTTAYSCQQGFCGTCKVRVLAGQVDRRGRIIEGDNEMLVCVSRAVSGRVVIDA
>NC_018078|1292015:1331492|1309828_1310512_+|WP_003414149.1|DBSCAN-SWA
MTVGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEFITVRHCARIALDQLGVPPAPILKGDKGEPCWPDGVVGSLTHCAGYRGAVVGRRDAVRSVGIDAEPHDVLPNGVLDAISLPAERADMPRTMPAALHWDRILFCAKEATYKAWFPLTKRWLGFEDAHITFETDSTGWTGRFVSRILIDGSTLSGPPLTTLRGRWSVERGLVLTAIVL
>NC_018078|1292015:1331492|1313599_1314805_+|WP_003414142.1|DBSCAN-SWA
MPNQGSSNKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVGYVYGESTSGQRALYELGMTGIPIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYKNHKHSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHNLAGRAVEIVGQAMTTDFASTFDGSARNIIGYDMTVQAAQRVYQQSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEAPELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVDNVTAALQHNIGLGGAAVVTAYQRAER
>NC_018078|1292015:1331492|1306461_1308150_+|WP_003414155.1|DBSCAN-SWA
MPLTVADIDRWNAQAVREVFHAASARAEVTFEASRQLAALSIFANSGGKTAEAAAHHNAGIRRDLDAHGNEALAVARAADRAADGIVKVQSELAALRHAAAAAELTIDALINRVVPIPGLRSTEAQWARTLAKQTELQAELDAIMAEANAVDEELASAVNMADGDAPIPADSGPPVGPEGLTPTQLASDANEERLREERARLQAHLERLQAEYDQLSVRAARDYHNGILDGDAVGRLAALTDELSAARGRLGELDAVDEALSRAPETYLTQLQIPEDPNQQVLAAVAVGNPDTAANVSVTVPGVGSTTRGALPGMVTEARDLRSEVIRQLNAAGKPASVATIAWMGYHPPPNPLDTGSAGDLWQTMTDGQAHAGAADLSRYLQQVRANNPSGHLTVLGHSYGSLTASLALQDLDAQSAHPVNDVVFYGSPGLELYSPAQLGLDHGHAYVMQAPHDLITNLVAPLAPLHGWGLDPYLTPGFTELSSQAGFDPGGIWRDGVYAHGDYPRSFLDAAGQPQLRMSGYNLAAIAAGLPDNTVGPPLLPPILGGGMPAAPGPALRGGR
>NC_018078|1292015:1331492|1301479_1301755_-|WP_003911993.1|DBSCAN-SWA
MPETLTGRLNFRLSPEQEQALRHAAALTGQSLSGFVLSAAVDHAHDLLARANRIELSEAAFRRFVAALDEPDEAAPELVRLARRKSRIPPH
>NC_018078|1292015:1331492|1306131_1306458_+|WP_003414157.1|DBSCAN-SWA
MFQISPEQWMHSAAQVTTQGEGLAVGHLSSDYRMQAAQFGWQGASAMALNAKMDDWLDASRALLTRIGDHAFGLQEAAIQHAAAEAERAQALAQVGVSADVVAGPRGV
>NC_018078|1292015:1331492|1316123_1316810_-|WP_003414136.1|DBSCAN-SWA
MRADEEPGDLSAVAQDYLKVIWTAQEWSQDKVSTKMLAERIGVSASTASESIRKLAEQGLVDHEKYGAVTLTDSGRRAALAMVRRHRLLETFLVNELGYRWDEVHDEAEVLEHAVSDRLMARIDAKLGFPQRDPHGDPIPGADGQVPTPPARQLWACRDGDTGTVARISDADPQMLRYFASIGISLDSRLRVLARREFAGMISVAIDSADGATVDLGSPAAQAIWVVS
>NC_018078|1292015:1331492|1328213_1329284_+|WP_003414107.1|DBSCAN-SWA
MNVEVHSAPGWRAGSSPLGYAQLYLPTRDVYWGDMSGIYVNAVATFSEGAAMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDWTNLPFHYVPNEPMATHVLNVLHMLLPAGEEFFVRVFKKTLPLIKDDQLRLDVQGFIGQEAMHSQAHSGVVDHFDAQGVDVTAFTNQIRWLFEKLLGESPRRSPRRQYSWLLEQVSFIAAIEHYTAVMGEWILNSPQLDAVGADPVMLDMLRWHGAEEVEHKAVAFDTMKHLRAGYWRQVRAQLTVTPVMLLLWIRGVRFMYSVDPYLPPGTKPRWRDYFKAARRGLVPGLPRLLRVVGHYYKPGFHPSQLGGLGAAVDYLAVSPAARASH
>NC_018078|1292015:1331492|1300309_1300501_-|WP_003414184.1|DBSCAN-SWA
MKTNPRYGPAFYSVMTVLFLALFVLNVCTHGSTLGLISTGGLAVLMGYIGYRGWSGKRHINRQ
>NC_018078|1292015:1331492|1310508_1311405_+|WP_003414147.1|tRNA|DBSCAN-SWA
MSATGPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARDLGDALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFARRDLTAAEASAAANGRSLPAVGIDGVYAACDADGRVIALLRDEGSRTRSVAVLRPATMHPG
>NC_018078|1292015:1331492|1327585_1328056_+|WP_003899475.1|DBSCAN-SWA
MPDPDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMATGVKDRASVNTEHIRRTLQRLKDRAEAG
>NC_018078|1292015:1331492|1298465_1298723_-|WP_003899489.1|DBSCAN-SWA
MSNVLDAISTEHRPVIEQELENRNPALFDELRRTEKPTNEQSDAVIDVLSDALMKTFGPDWVPNDYGLKIERAIDAYLETWPIYR
>NC_018078|1292015:1331492|1295541_1296951_-|WP_003414198.1|integrase,transposase|DBSCAN-SWA
MAVGDDEEKVRAERARAIGLFRYQLIWEAADAAHSTKQRGKMVRELASREHTDPFGRRVRISRQTIDRWIRGWRAGGFDALVPNPRQCTPRTPAEVLELAVALRRENPQRTAAAIRRILRTQLGWAPDERTLQRNFHRLGLTGATTGSAPAVFGRFEAEHPNALWTGDVLHGIRIDLRKTYLFAFLDDHSRLVPGYRWGHAEDTVRLAAALRPALASRGVPNAVYVDNGSPYVDAWLLRACAKLGVRLVHSTPGRPQGRGKIERFFRTVREQFLVEITGEPDVVGRHYVADLAELNRLFTAWVETVYHRSVHSETGQTPLARWSAGGPIPLPAPETLTEAFLWEEHRRVTKTATVSLHGNRYEIDPALVGRKVELVFDPFDLTRIEVRLAGAPMGRAIPYHIGRHSHPKAKPETPTAPPKPSGIDYAQLIETAHAAELARGVNYTALTGAADQIPGQLDLLTGQEAQPK
>NC_018078|1292015:1331492|1318868_1319864_+|WP_003414131.1|DBSCAN-SWA
MRRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARGVPAVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELVQDLGIEVFLVMPFTTDFMKLTPDRFIHELLVEHLHVVEVVVGENFTFGKKAAGNVDTLRRAGERFGFAVESMSLVSEHHSNETVTFSSTYIRSCVDAGDMVAAMEALGRPHRVEGVVVRGEGRGAELGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVTGTVVPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTTADLYGQHVALDFVGRIRGQKKFESVRQLVAAMGADTERARDLLSTG
>NC_018078|1292015:1331492|1303245_1303602_+|WP_003414166.1|DBSCAN-SWA
MMRRGEIWQVDLDPARGSEANNQRPAVVVSNDRANATATRLGRGVITVVPVTSNIAKVYPFQVLLSATTTGLQVDCKAQAEQIRSIATERLLRPIGRVSAAELAQLDEALKLHLDLWS
>NC_018078|1292015:1331492|1297021_1297630_-|WP_003414195.1|DBSCAN-SWA
MVTVEADVDQVERRLAAGELSCPSCGGVLAGWGRARSRQLRGPAGPVELCPRRSRCTGCGVTHVLLPVSALLRRADTAAVIVSALAAKATSRVGFRRIATDVARPAETVRGWLRRFAERVEAVRSVFTVWLCAVDADPVMPDAGGGGFVDAVVAIGALAAAIGRRFSLPTVSLAETAVAVSGGRLLAPGWPGEWVQHESTLP
>NC_018078|1292015:1331492|1305371_1306001_-|WP_003414158.1|DBSCAN-SWA
MYTPGKGPPRAGGVVFTRVRLIGGLGALTAAVVVVGTVGWQGIPPAPTGGDAVQLRSTAAPMSTTMKSPIVATTDPSPFDPCRDIPFDVIQRLGLAYTPPEAEEGLRCHFDAGNYQMAVEPIIWRTYAQTLPPDAIETTIAGHRAAQYWVRKPTYHNSFWYSSCMVTFKTSYGVIQQSLFYSTVYSEPDVDCPSTNLQRANDLVPYYRF
>NC_018078|1292015:1331492|1314830_1316063_+|WP_003414139.1|DBSCAN-SWA
MFEWSDTDLMVRDAVRQFIDKEIRPHQDALETGELSPYPIARKLFSQFGLDVLLAESVNQMLDGERAKREKRDSSGSFGLADQASMVAVLVSELAGVSIGLLSTVAVSLGLGAATIMSRGTLAQQERWVPTLVTLEKIAAWAITEPDSGSDAFGGMKTHVTRDGEDYILNGHKTFITNGPYADVLVVYAKLADGEPASDWRNRPVLVFVLDAGMPGLTQGKPFKKMGMMSSPTGELFFDNVRLTPDRLLCAEGDGRDSARANFAVERLGVALMSLGIINECHRLCVDYAKTRTLWGRNIGQFQLIQLKLAKMEVARINVQNMVFQAIERLKAGKQLTLAEASAIKLYSSEAATDVAMEAVQLFGGNGYMAEYRVEQLARDAKSLMIYAGSNEVQVTHIAKGLLGEPASRA
>NC_018078|1292015:1331492|1312187_1313567_+|WP_003906908.1|transposase|DBSCAN-SWA
MAKFEIPEGWMVQAFRFTLDPTAEQARALARHFGARRKAYNWTVATLKADIDAWQATGIQTAKPSLRVLRKRWNTVKNDVCVNIETGVVWWPECSKEAYADGIDGAVDAYWNWQNSRSGKRDGKRMGFPRFKKKGRDPDRVTFTTGAMRVEPDRSHLTLPVIGTVRTHENTRRVERLIAKGRSRVLAITVRRNGTRIDASVRVLVQRPQQPKVTDPGSRVGVDVGVRRLATVATADGAVLERVPNPRPLDAALNELRHVCRARSRCTKGSRRYRERTTEISRLHRRVNDVRTHHLHCLTTHLAKTHGRIVVEGLDAAGMLRQQGLSGARARRRGLSDAALGTPRRHLSYKTGWYGSQLVVADRWFPSSKTCHVCGHVQEIGWAEHWQCDSCSASHQRDDCAAINLARYEDTSSVVGPVGAAVKRGADRKTRPGRAGGREARKGSSRKAAEQPRDGVQVA
>NC_018078|1292015:1331492|1311606_1312188_+|WP_003414146.1|transposase|DBSCAN-SWA
MNLAVWAERNGVARVTAYRWFHAGLLPVPARKAGRLILVDDQPADRSRRARTAVYARVSSADQKPDLDRQVARVTAWATTEQIAVDKVVTEVGSALNGHRRKFLALLRDPSVKRIVVEHRDRFCRFGSEYVEAALAAQGRELVVVDSAEVDDDLVRDMTEILTSMCARLYGKRAAQNRAKRALAAAAEESEAA
>NC_018078|1292015:1331492|1320302_1320818_+|WP_003899480.1|DBSCAN-SWA
MRAWLAAATTALFVVATGCSSATNVAELKVGDCVKLAGTPDRPQATKAECGSPASNFKVVAVVQEDHAECPADVDSTYSMRNAFNGSTNTICLDIDWVIGGCMSVDPTHNTDPFRVDCDDASVPHRQRATQILKDLDSPVSVDQCASGVGYVYTQRRFAVCVEDVTGGPRS
>NC_018078|1292015:1331492|1327014_1327554_+|WP_003899476.1|DBSCAN-SWA
MIILFRGHMRDNSTEHKTRRAASSKDVRPAELDEVDRRILSLLHGDARMPNNALADTVGIAPSTCHGRVRRLVDLGVIRGFYTDIDPVAVGLPLQAMISVNLQSSARGKIRSFIQQIRRKRQVMDVYFLAGADDFILHVAARDTEDLRSFVVENLNADADVAGTQTSLIFEHLRGAAPI
>NC_018078|1292015:1331492|1301945_1302989_+|WP_003414172.1|DBSCAN-SWA
MARQPLEQRVARAAQAALARQRFVSAIDVLLGLGWLAPSHVDQWRQGRVDSLEQVVQANLSKITAVMAALRRWARDRGLNPSETDYVARTRDRRRLRFSVTGEDAIERAYRTHWVSPELSERAVARQSRRPDLVVIMPVNDWSCASCGGSGDLMFLEDAGPLCLDCADLGHLVFLPSGDAALTRRAKRASRLSAVVVRWSRARKRYERQGILVEAEALERAENECLADAEVRARRRERDEARRANEDLRLQAEFGAAIRTLFPNCPAGRAEAIARHAATRGSGRIGRSAAGRALDPEAVRLAVAASVRHIDTSFDELLMSGVDRETARHRVGEHVEEVLRDWRATSR
>NC_018078|1292015:1331492|1294732_1295545_-|WP_003899491.1|DBSCAN-SWA
MMHKLISYYGFSRMPFGRDLAPGMLHRHSAHNEAVARIGWCIADRRIGVITGEVGAGKTVAVRAALASLDRSRHTIIYLPDPTVGVQGIHHRIVASLGGQPLTHHATLAPQAADALAAEQAERGRTPVVVVEEAHLLGYDQLEALRLLTNHDLDSSSPFACLLIGQPTLRRRMKLGVLAALDQRIGLRYAMPPMTDTNTGSYLRHHLKLAGRDDALFSDDAIGLIHQTSRGYPRAVNNLALQALVAAFAADKAIVDESTTRTAIAEVTAD
>NC_018078|1292015:1331492|1298049_1298361_-|WP_003414190.1|DBSCAN-SWA
MTYAARDDTTLPKLLAQMRWVVLVDKRQLAVLLLENEGPVASATDTLDTRGDSDYENQPVDAVERLCRRLADQAVRQWGFMQGLKQKLGPGVDVRMKLVEWNR
>NC_018078|1292015:1331492|1316894_1318658_-|WP_003414134.1|DBSCAN-SWA
MSTFRECRSMFDAAVKSYQSGDLANARAAFGRLTVENPDMSDGWLGLLACGDHHLDTLAGAHQHSEALYSETRRVGLTDGELSAVVMAPMYLGLRVWSRATIGLAYASALIIADRHDEAAATLDDPVITEDTGAAQYRQFVMATLFHKTRSWSNLLKVTEISPPSGATDVRDEVADAVAALASTAAASLGQFQFALELAEQVSTTNPRVTADVTLTRAWCLRELGDDDAARVALSATTTGDAPRTNTTAEQAGSPQPKFRHPYDDGRDLLVARRRPPAGDGWRKAVTKMTFGRVNPEPSAKREQTDELIQRICAPLADVHKLAFVSAKGGVGKTTMTVLVGNAVARLRGDRVMAVDVDADLGDLSARFSERGGPQTNIEHFVSSQHTKRYADVRVHTVMNKDRLEMLGAQNDPRSTYKFGPEDYGAAMQILETHCNVILLDCGTPVNGPLFSNILNDVTGLVVVASEDVRGVEGALVTLDWLGAHGFGRLLQHTVVVLNAIQKTRSLVDCGAAENQFRKRVPDFFRIPYDPHLATGLAVDFSSLKRRTRNAVLDLAGGLAQHYPASRVRPRGEDSWKTWIETMRQVG
>NC_018078|1292015:1331492|1320020_1320290_+|WP_003414128.1|DBSCAN-SWA
MALTAEQKKEILRSYGLHETDTGSPEAQIALLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLIKYISQIDVERYRSLIERLGLRR
>NC_018078|1292015:1331492|1323407_1324724_+|WP_003414119.1|DBSCAN-SWA
MPRRSPADPAAALAPRRTTLPGGLRVVTEFLPAVHSASVGVWVGVGSRDEGATVAGAAHFLEHLLFKSTPTRSAVDIAQAMDAVGGELNAFTAKEHTCYYAHVLGSDLPLAVDLVADVVLNGRCAADDVEVERDVVLEEIAMRDDDPEDALADMFLAALFGDHPVGRPVIGSAQSVSVMTRAQLQSFHLRRYTPERMVVAAAGNVDHDGLVALVREHFGSRLVRGRRPVAPRKGTGRVNGSPRLTLVSRDAEQTHVSLGIRTPGRGWEHRWALSVLHTALGGGLSSRLFQEVRETRGLAYSVYSALDLFADSGALSVYAACLPERFADVMRVTADVLESVARDGITEAECGIAKGSLRGGLVLGLEDSSSRMSRLGRSELNYGKHRSIEHTLRQIEQVTVEEVNAVARHLLSRRYGAAVLGPHGSKRSLPQQLRAMVG
>NC_018078|1292015:1331492|1308149_1308713_+|WP_003900574.1|DBSCAN-SWA
MRWPTAWLLALVCVMATGCGPSGHGTRAGEEGPLSPEKVAELENPLRAKPPLEDAKDQYRAAVTQLANAITALVPGLTWRTDMDTWTGCGGEYEWTRAKAAYFMIVFSGPIPDDKWLQAVQIVKDGVEQFGATGFGVMKNKPADHDVYFAGHGGVEFKCSTQKAAVLTAQSDCRISRTDTPKPSPTP
>NC_018078|1292015:1331492|1321171_1323430_+|WP_003414124.1|DBSCAN-SWA
MSAAEIDEGVFETTATIDNGSFGTRTIRFETGRLALQAAGAVVAYLDDDNMLLSATTASKNPKEHFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTDAILTCRLIDRPLRPSFVDGLRNEIQIVVTILSLDPGDLYDVLAINAASASTQLGGLPFSGPIGGVRVALIDGTWVGFPTVDQIERAVFDMVVAGRIVEGDVAIMMVEAEATENVVELVEGGAQAPTESVVAAGLEAAKPFIAALCTAQQELADAAGKSGKPTVDFPVFPDYGEDVYYSVSSVATDELAAALTIGGKAERDQRIDEIKTQVVQRLADTYEGREKEVGAALRALTKKLVRQRILTDHFRIDGRGITDIRALSAEVAVVPRAHGSALFERGETQILGVTTLDMIKMAQQIDSLGPETSKRYMHHYNFPPFSTGETGRVGSPKRREIGHGALAERALVPVLPSVEEFPYAIRQVSEALGSNGSTSMGSVCASTLALLNAGVPLKAPVAGIAMGLVSDDIQVEGAVDGVVERRFVTLTDILGAEDAFGDMDFKVAGTKDFVTALQLDTKLDGIPSQVLAGALEQAKDARLTILEVMAEAIDRPDEMSPYAPRVTTIKVPVDKIGEVIGPKGKVINAITEETGAQISIEDDGTVFVGATDGPSAQAAIDKINAIANPQLPTVGERFLGTVVKTTDFGAFVSLLPGRDGLVHISKLGKGKRIAKVEDVVNVGDKLRVEIADIDKRGKISLILVADEDSTAAATDAATVTS
>NC_018078|1292015:1331492|1303703_1305353_-|WP_003899485.1|DBSCAN-SWA
MSTTSARPERPKLRALTGRVGGQALGGLLGLPRATTRYTVGHVRVPMRDGVQLVADHYAPATSQPVGTLLVRGPYGRRFPFSLVFARIYAARGYHVVLQSVRGTFGSGGVFEPMVNEAADGADTVAWLREQPWFTGRFGTIGLPYLGFTQWALLHDPPPELAAAVITVGPHDFRASVWGTGSFTVNDFLGWSDLVSHQEDPGRIRAGIRQLTAPRRVARTAATLPLGESARTLLGTGAPWFESWVEHTDRDDPFWDRLRFPAALDRVQVPVLLVGGWQDIFLRQTLQQYRHLRDRGVHVALTVGPWTHTQMLTKGLATGARESLDWLDAHLGRAPALRPSPVRVFVTGQGWRHLPDWPPATTERAWYLQPGGRLGESAPASGTPPATFRYHPADPTPTTGGPLLSSNGGYRDDSRLATRADVLCFTGAPLTHDLCVHGNPVVELVHSSDNPYVDVFVRVSEVDAKGRSRNVSDGYRRLGDAPELVRVELDAIAHRFRADSRIRVLIAGSWFPRYARNLGTPEPILTGRQLKPATHAVHFGRSRLLLPVG
>NC_018078|1292015:1331492|1330607_1331492_-|WP_003899492.1|transposase|DBSCAN-SWA
MRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG
>NC_018078|1292015:1331492|1325833_1326949_-|WP_003899477.1|DBSCAN-SWA
MRVGIPTETKNNEFRVAITPAGVAELTRRGHEVLIQAGAGEGSAITDADFKAAGAQLVGTADQVWADADLLLKVKEPIAAEYGRLRHGQILFTFLHLAASRACTDALLDSGTTSIAYETVQTADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAVLVPGAKAPKLVSNSLVAHMKPGAVLVDIAIDQGGCFEGSRPTTYDHPTFAVHDTLFYCVANMPASVPKTSTYALTNATMPYVLELADHGWRAACRSNPALAKGLSTHEGALLSERVATDLGVPFTEPASVLA
>NC_018078|1292015:1331492|1324784_1325819_+|WP_003899478.1|DBSCAN-SWA
MVLGFWDIAVPIVGAPMAGGPSTPALAAAVSNAGGLGFVAGGYLSADRLADDIAAARAATTGPIGANLFVPQPSVADWAQLEYYADELEEVAEYYHTEVGQPVYGDDDDWVRKLEVVADVRPEVVSFTFGAPPPDVVQRLSALGLLVSITVTSVYEAGVAIAAGADSLVVQGPAAGGHRGTFAPDMEPGTESLHQLLDRIGSAHDVPLVAAGGLGTAEDVAAVLRRGAIAAQVGTALLLADEAGTNAAHRAALKNPEFDATLVTRAFSGRYARGLANNFTRLLDHVAPLGYPEVHQMTKPIRAAAVQADDPHGTNLWAGSAHRKTRPGPAADIIASLTPDVCSA
>NC_018078|1292015:1331492|1301049_1301304_+|WP_003917684.1|DBSCAN-SWA
MTVELGGAVVDGVDDQGAGAVVPGTGHGSDEGIEEKIATETGALLLPVERQASEDEHWDRVGSGWPRPGRDGTRIRSMLPMASA
>NC_018078|1292015:1331492|1300497_1300902_-|WP_009938577.1|DBSCAN-SWA
MGRGNGKILDPVVATTGMGRSTARQMLTGPRLPGPAEQVDGRSLRPRGFSDEARALLEHVWALMGMPCGKYLVVMHDLWLPLLTAAGDLDKPLVTEASVAELKATALPGANRMPHWAAGTLPDGFPARAVRTRT
>NC_018078|1292015:1331492|1298956_1300111_-|WP_003899488.1|integrase,transposase|DBSCAN-SWA
MVSTTGMGRSTARRMLTGPGLPEPAEQVDGRRLRARGFSDDARALLEHVWALMGMPCGKYLVVMLELWLPLVAAAGDLDKPFATEAAVAELKAMSAATVDRYLKPARERMRIKGISTTKPSPLLRNSITIHTCSDEAPKVPGVIEADTVAHCGPSLIGEFARTLTMTDLVTGWTENASIRNNAAKWILEGIKECQQRFPFPMTVFDSDCGGEFINHDVAGWLQARDIAQTRSRPYQKNDQAHVESKNNHVVRKHAFYWRYDTGEELELLNRLWPLVSLRCNFFTPTKKPVGYTSTVNGRRKRIYDKPATPWQRLQASGVLDAQQLSTVAARIEGFNPADLTRQINAIQMQLLDLAKTKTEALATARHIDLQSLQPSINRLAKAK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1291965:1292024	attL	NA	NA	NA	NA
WP_087902221.1|1292015_1293276_+|transposase	IS3-like element IS987 family transposase	Q8W6R2	Burkholderia_virus	9.6e-83	59.1
WP_003899491.1|1294732_1295545_-	AAA family ATPase	NA	NA	NA	NA
WP_003414198.1|1295541_1296951_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_003414195.1|1297021_1297630_-	hypothetical protein	NA	NA	NA	NA
WP_003414190.1|1298049_1298361_-	hypothetical protein	NA	NA	NA	NA
WP_003899489.1|1298465_1298723_-	hypothetical protein	NA	NA	NA	NA
WP_003899488.1|1298956_1300111_-|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_003414184.1|1300309_1300501_-	hypothetical protein	NA	NA	NA	NA
WP_009938577.1|1300497_1300902_-	hypothetical protein	NA	NA	NA	NA
WP_003917684.1|1301049_1301304_+	hypothetical protein	NA	NA	NA	NA
WP_003911993.1|1301479_1301755_-	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_003414172.1|1301945_1302989_+	DUF2293 domain-containing protein	NA	NA	NA	NA
WP_003901465.1|1303031_1303262_+	antitoxin MazE	NA	NA	NA	NA
WP_003414166.1|1303245_1303602_+	type II toxin-antitoxin system toxin endoribonuclease MazF9	NA	NA	NA	NA
WP_003899485.1|1303703_1305353_-	CocE/NonD family hydrolase	NA	NA	NA	NA
WP_003414158.1|1305371_1306001_-	DUF3558 domain-containing protein	NA	NA	NA	NA
WP_003414157.1|1306131_1306458_+	hypothetical protein	NA	NA	NA	NA
WP_003414155.1|1306461_1308150_+	hypothetical protein	NA	NA	NA	NA
WP_003900574.1|1308149_1308713_+	hypothetical protein	NA	NA	NA	NA
WP_003414151.1|1308857_1309832_+	metallophosphoesterase	NA	NA	NA	NA
WP_003414149.1|1309828_1310512_+	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_003414147.1|1310508_1311405_+|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_003414146.1|1311606_1312188_+|transposase	IS607-like element IS1602 family transposase	F9VHY9	Thermus_phage	5.0e-18	30.6
WP_003906908.1|1312187_1313567_+|transposase	transposase	A0A7P9	Microcystis_virus	7.2e-31	30.3
WP_003414142.1|1313599_1314805_+	lipid-transfer protein	NA	NA	NA	NA
WP_003414139.1|1314830_1316063_+	acyl-CoA/acyl-ACP dehydrogenase	NA	NA	NA	NA
WP_003414136.1|1316123_1316810_-	manganese-binding transcriptional regulator MntR	NA	NA	NA	NA
WP_003414134.1|1316894_1318658_-	AAA family ATPase	NA	NA	NA	NA
WP_003414131.1|1318868_1319864_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_003414128.1|1320020_1320290_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_003899480.1|1320302_1320818_+	hypothetical protein	NA	NA	NA	NA
WP_003414124.1|1321171_1323430_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_003414119.1|1323407_1324724_+	insulinase family protein	J3IZ03	Acanthamoeba_polyphaga_lentillevirus	5.4e-28	24.4
WP_003899478.1|1324784_1325819_+	nitronate monooxygenase	NA	NA	NA	NA
WP_003899477.1|1325833_1326949_-	alanine dehydrogenase	NA	NA	NA	NA
WP_003899476.1|1327014_1327554_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_003899475.1|1327585_1328056_+	SRPBCC family protein	NA	NA	NA	NA
WP_003414107.1|1328213_1329284_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_003414104.1|1329465_1330395_+	oxidoreductase	NA	NA	NA	NA
WP_003899492.1|1330607_1331492_-|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	6.7e-83	59.1
1331861:1333216	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_018078|1430630:1443376|DBSCAN-SWA
CTCAGCCGGCATCGGTTGCGCCGGCATCGGTTGCGCCGGCAGCGTTGGCGCCGGTGAGCGATGCGAGCGTGGTGATCAGGTCGGCCTCGGCGCGGCTCTTGTCGACGCCGGATCGATGCAACGGCCCATCCCCGTCCTCGAGTTCTAGCAGTGCCAGCAGCAGGTGTTCGGTCCCGATGTAGTTGTGGCCCAGCCGAAGCGCCTCGCGGAAGGTGAGCTCGAGGACCTTGCGCGCCGGGCCGCTGAACGGGATCGGCTGAGGCGGCTCGGTGACTGCCGGGGGGAGCGTGACCGCCGTACGCAGGGTTGCGATGTCGATCTCCTGCTGCTGAAGCAACGCCGTGGCCAGTGCGGCCGGGTCAGTGAGCACTCCCAACAACAGGTGATCGGGGGTGATCTCGCTGCTGGCGGCTCCGTGCGCGGCGTTTTGGGCCGCGACCACGGCGTTGCGGGCCCGCGGCGTGAAACGCCTGAAGCCCTGGTTTGAATCCAGTGTGGTGGCTTCGGCTCGGGGGACGAACCGCTTTTGCGCGGCCTGTTTGGTGACGCCCATGCTCTTGCCGATATCGGACCAGGAGGCGCCCGAGCGGCGGGCCTGATCGACGAAGTGGCCGATTAAGTGATCGGCGATTTCGCCGAGATGCTCGGCGGCCAGGACGGCGTCGCTGAGTTGGTCCAACACGTCGCTGTGCACCCGTTTGATGGCGTTGATGAGCTCGTCGAGGCGGACGGGGTAGGCGGTGGGTGTGGGCTCCGGCATGACGTCAACAGTAGGTTGACGTTATGCATTGTGTCGACCGTGATTGGCTGCGTAGTGGGTTCTGCAGCGCTGCCAGGCCGCTGCGGGCAGGGTGGCGCCGATCGCGGCCACCAGGCCGGCGTGGGCGTCGCTGGTGACCAGCGCGACCCCGGACAGGCCGCGGGCGACCAGGTCGCGGAAGAACGCCAGCCAGCCGGCCCCGTCCTCGGCGGAGGTGACCTGGATGCCCAGGATCTCTCGGTAGCCCTCGGCGTTGACGCCGGTGGCGATCAAGGTGTGCACCCCGACGACGCGGCCTGCCTCGCGCACCTTGAGCACCAGGGCGTCGGCGGCGAGGAAGGTATACGGGCCGGCATCGAGCGGGCGGGTCCGAAACGCCTCTACGGCTTCGTCGAGCTCTTTGGCCATGATCGACACTTGCGACTTGGAAAGCTTTGTCACACCAAGTGTTTCGACCAGGCGCTCCATCCGGCGAGTGGATACTCCCAGCAGGTAGCAGGTCGCCACCACGCTGGTCAGTGCGCGTTCAGCTCGCTTGCGGCGCTGCAGCAGCCAGTCCGGGAAATAGCTGCCCTGGCGCAGCTTGGGGATCGCGACGTCGATGGTTGCGGCACGGGTGTCGAAATCACGGTGGCGGTAGCCGTTGCGCTGATTGGACCGCTCATCGCTGCGTTCGCGGTAGCCCGCCCCGCACAGGGCGTCGGCTTCAGCCCCCATCAAGGCGGCGATGAACGTCGAGAGCAGCCCGCGCAGCAGATCCGGGCTCGCCTGTGCGAGTTGGTCAGCCAGAAGCTGCTCGGTGTCGATAAGATGAGAAGAGGTCATTGCGTCATTTCCTTCGATTGACTTTTGCTGGTCGTTTCGAAGGATCACGCGATGACCGCCCACTACTGGGCTACGACACGCCCACCGGCCTTACCTGCCCGTACACCACACCCCTGGACGTAACTGGCCGCCGCCGCCGCGCCCTAGGCGTGGCTGTAGCGCCGCTGGCAGGAGCACATGGGTGCTTTCGCATCTGCGGCAACGCACCCGCTGGGGCCGCACATCGATCACCTGCGAGCCGAGGCTGCGCACATGCCGGCGCCGTCCATATCGCCACCGCCGCAAGGTGTCGCCACATCCGCGGCGGGGGCAGACCAGCTGGCCCTCAGTCAGGGCCTGCTCGGCCGCCTCGGCCGTACGGACGACGATCATCGGGTGCTCCGGTGCGCATGACCCACCAGCGTGGTCTATCACGTCCTGGCCAGGAAGGGGCCAACTGGTGTTGCTGTCAGAGGAATCAAGCCCATCGCCAAAACCGGCAAACACAATAAGTGATCGACCAGAACAAACGAAATTTTAGCAAACACACTCAGGAGACGGCGGGTCGCCGTGTCGCTGTGTGTAGGGGTCTGGGGATTTGTACGGGTCTGGGGTTGTGGGGGACAGCAAACACAAAACCCATGCCTAGCAAACACGACGCCACGTGTGTCGGCCAGACGCTGTGACTCCGCTTCGGCCCTGTCTGGTCGTCGTCAACTCCACCGCGGAGGCGCGCCGGTTTAGGGGCTCGCTGTGCTGTGTGGCCCGAACCGTTGGAACGCGGCCTGGCGGGTGATGCCGAGGGCGACGCCGATGGCTGCCCAGGTGTCGCCGGCGGCGCGGGCAGCATTCACTGCGGCCCGCAACTCAGATTCGGCTGTTTGGACCGCTTCTTTCGCGGCGATGATGCGCCGCAGGTGGCTGGCATCGTGGGCGTCGGCCGGGTTGGGCTCGATCGTGTCGAGCCACTCGTCAATGTCGGTCTTGTGCTTCACTCTTATCTCATCACCTCAGGTAGTCGTAGAACTTCGGGCGTAGTACGTTGGCGTGGATAATCCGGGGTGGTTCGTCTGCTGGGATGACCAGCTCTAAAAGGCGCCCGGTTTGGTCGGGGCCGATCACCAGCAGTTGAACTTCGCCGTGGTATTCCAGTTCGACGTAGCGCAGCGCGTTGCGGTATGCGTGGAGCATGGCGTCGTCGTTGATGCCGTGCTTGCGGGCGCTAGCCCTCACCTCCACGTGTAAACGTTACCTTTACAACAGGCTGCCGTAAAGAATGGCTTACAGCCCACTGGCGGCTACTCGGGTCAGGTCGGTCAATTGCCACGCGCAGGCCGCTACGGTGGGCGGCACTGTTTCTCACCAGCGCAAACAGAAGAGTCCCCACCGTTTCCGATAGGGGCTGCTCTCGCGGATGGGTTGGTGGTTAATCGCACGAGTCGGAGTCGAGGCCCTCCGGGCGATACAGGCTGTGGCGGGCTGGCCGTCATGTCGATCCAGGGGTCGTAGGTCGCGATGAGGGCTCGCAGCGATGCTGGAGGCCAGTCTGTGAAGTCCCGCACGTCGAATCGGTCCAGAAGCTCGCGCCGGAGCCGCGTCAGGTCATCCATCAGTGCCCTCGTTGATAATCCGCAGGCTCGGCCGCGCGAGCTCCCTGTTCTGTGCGGGTGGCCCGTAGTGCGCGTCGAGCCGGTCTGCGAGTTCGTGCCGGAGCCGGTTTGTGGACAGGCCGAGGTGCTCGGCGAGCCAGCCGCCGCTCATCGGGTCACCTCAGCCCGCCGGTCACCCTCAACGACCGTTTGCAGCCGTTCGCAGAAGGCGAGCGCGGTGGTGATCAGCTCCGTCAGCTCGGTTGCGCGGGTGCGGCGTGCCTCGGTGAGTTCGGTGGACGCGACAACAGCGTGATAGCGGGCGTCGACCAGGCGCTTGCAGCAACAGGCCAGGCTAGCCAGCGGGCGGCAGGCGCATCTGGTGGGGTCACCGTCGGTGTCGGCGTGGGCACGGAACAGAGGAACCTTTCGGTGGTTGCACCGAGTCAGTTCACATTTAGTTCACGCAGCCCAGATTTTGTGGATGAAACCGCAGGTCAATCGTGGTGCGCGATACTGGGATTGAACCAGTTTCACTAGTGGGCCGGTGGGATACTGTCTGACCTGTACAGAAAGCCTCTGACCAGGCGACATAGACAACAGTACCCCCGGAAGCGTGCGGAAGCAAGCGGCATCTGATGTAGTCTCTTATTGCGCGTTTATTGCGCGGGACAGGGGACGACAGTGACGCAAACCGGCAAGCGTCAGAGACGCAAATTCGGTCGCATCCGACAGTTCAACTCCGGCCGCTGGCAAGCCAGCTACACCGGCCCCGACGGCCGCGTGTACATCGCCCCCAAAACCTTCAACGCCAAGATCGACGCCGAAGCATGGCTCACCGACCGCCGCCGCGAAATCGACCGACAACTATGGTCCCCGGCATCGGGTCAGGAAGACCGCCCCGGAGCCCCATTCGGTGAGTACGCCGAAGGATGGCTGAAGCAGCGTGGAATCAAGGACCGCACCCGCGCCCACTATCGCAAACTGCTGGACAACCACATCCTGGCCACCTTCGCTGACACCGACCTACGCGACATCACCCCGGCCGCCGTGCGCCGCTGGTACGCCACCACCGCCGTGGGCACACCGACCATGCGGGCACACTCCTACAGCTTGCTGCGCGCAATCATGCAGACCGCCTTGGCCGACGACCTGATCGACTCCAACCCCTGCCGCATCTCAGGCGCGTCCACCGCCCGCCGCGTCCACAAGATCAGGCCCGCCACCCTCGACGAGCTGGAAACCATCACCAAAGCCATGCCCGACCCCTACCAGGCGTTCGTGCTGATGGCGGCATGGCTGGCCATGCGCTACGGCGAGCTGACCGAATTACGCCGCAAAGACATCGACCTGCACGGCGAGGTTGCGCGGGTGCGGCGGGCTGTCGTTCGGGTGGGCGAAGGCTTCAAGGTGACGACACCGAAAAGCGATGCGGGAGTGCGCGACATAAGTATCCCGCCACATCTGATACCCGCCATCGAAGACCACCTTCACAAACACGTCAACCCCGGCCGGGAGTCCCTGCTGTTCCCATCGGTCAACGACCCCAACCGTCACCTAGCACCCTCGGCGCTGTACCGCATGTTCTACAAGGCCCGAAAAGCCGCCGGCCGACCAGACTTACGGGTGCACGACCTTCGACACTCCGGCGCCGTGTTGGCTGCATCCACCGGCGCCACACTGGCCGAACTGATGCAGCGGCTAGGACACAGCACAGCCGGCGCCGCACTCCGCTACCAGCACGCCGCCAAGGGCCGGGACCGCGAAATCGCCGCACTGTTAAGCAAACTGGCCGAGAACCAGGAGATGTGATGATGGCCGATGCGGTTAAGTACGTAGTTATGTGCAACTGCGACGACGAACCGGGAGCGCTCATCATCGCCTGGATCGACGACGAACGACCCGCCGGCGGGCACATACAGATGCGGTCGAACACCCGCTTCACCGAAACACAGTGGGGCCGCCATATCGAGTGGAAACTCGAATGCCGGGCATGCCGAAAGTATGCGCCGATATCCGAGATGACCGCCGCGGCGATCCTCGACGGTTTCGGGGCGAAGCTTCACGAGCTGAGAACGTCGACCATCCCCGACGCTGACGATCCATCAATAGCAGAGGCGCGACACGTAATTCCGTTCAGCGCATTATGCTTGCGCTTGAGCCAGCTAGGCGGGTAAATTTTCCGGTGCGCGCATGTGCGCGTTCCCGTCGCCGAGTCTCGGGTGGACGGTCTCTCACGAGACCGAAAGGCCCGGCATGGCAGACGCTCCCCCGTTGTCACGGCGGTACATCACGATCAGTGAGGCCGCCGAATATCTAGCGGTCACCGACCGCACGGTCCGCCAGATGATCGCCGACGGCCGCCTACGCGGATACCGCTCCGGCACCCGCCTCGTCCGTCTGCGCCGCGATGAGGTCGACGGCGCCATGCACCCGTTCGGTGGTGCCGCATGACCGCCGTCGGCGGGTCGCCGCCGACGCGACGATGCCCGGCCACAGAGGACCGGGCACCCGCGACAGTCGCCACACCGTCTAGCACCGATCCTACCGCGTCCCGCGCCGTGTCGTGGTGGTCGGTGCACGAGTATGTCGCACCGACCCTGGCCGCCGCCGTGGAATGGCCGATGGCCGGCACCCCGGCGTGGTGCGACCTCGACGACACCGACCCGGTCAAATGGGCCGCGATCTGCGACGCTGCTCGGCATTGGGCACTCCGGGTGGAGACGTGCCAGGCCGCGTCGGCCGAGGCATCACGTGACGTATCCGCCGCCGCCGACTGGCCGGCGGTCTCTCGGGAGATCCAGCGTCGGCGTGACGCCTACATTCGGCGGGTGGTGGTCTGAGATGGCTGACATCCCCTACGGCCGTGACTATCCCGACCCGATCTGGTGTGACGAGGACGGCCAGCCGATGCCGCCGGTCGGCGCCGAATTGCTCGACGACATTAGGGCATTCTTGCGGCGGTTCGTAGTCTATCCAAGCGACCATGAACTGATCGCGCACACCCTCTGGATTGCGCATTGCTGGTTTATGGAGGCGTGGGACTCAACGCCCCGAATCGCTTTTTTGTCACCGGAACCCGGCTCTGGCAAGAGCCGCGCACTCGAAGTCACGGAACCGCTAGTGCCCCGGCCGGTGCATGCCATCAACTGCACACCGGCCTACCTGTTCCGTCGGGTGGCCGATCCGGTCGGGCGGCCGACCGTCCTGTACGACGAGTGTGACACCCTGTTTGGCCCGAAAGCTAAAGAACACGAGGAAATTCGCGGCGTGATCAACGCCGGCCACCGCAAGGGAGCCGTCGCGGGCCGCTGCGTCATCCGCGGCAAGATCGTTGAGACCGAGGAACTGCCAGCGTACTGTGCGGTCGCCTTGGCCGGCCTCGACGACCTGCCCGACACCATCATGTCTCGGTCGATCGTGGTGAGGATGCGCAGGAGGGCACCAACCGAACCCGTGGAGCCGTGGCGCCCCCGCGTCAACGGCCCCGAGGCCGAGAAGCTGCACGACCGGTTGGCGAACTGGGCGGCCGCCATTAACCCGCTGGAAAGCGGTTGGCCGGCGATGCCGGACGGGGTGACCGACCGGCGCGCCGACGTCTGGGAGTCCCTGGTTGCGGTTGCTGACACCGCGGGCGGGCACTGGCCCAAAACCGCCCGTGCAACCGCAGAAACGGATGCAACCGCAAATCGAGGAGCCAAGCCCAGCATAGGCGTGCTGCTGCTGCGGGATATCCGTCGAGTCTTCAGCGACCGGGACCGGATGCGCACCAGCGACATCCTGACCGGACTGAACCGGATGGAGGAGGGACCGTGGGGCTCCATCCGCCGCGGCGACCCGCTCGACGCGCGCGGCCTCGCGACCCGGCTCGGCAGATACGGCATCGGGCCGAAGTTCCAGCACAGTGGTGGCGAACCACCCTACAAAGGGTATTCGCGGACCCAGTTCGAGGATGCGTGGTCCCGGTATCTCTCTGCCGACGACGAAACCCCCGAGGAACGAGATTTATCGGTTTCCGCGGTTTCCGCGGTTTCACCGCCGGTTGGCGATCCCGGTGATGCAACCGGCGCAACCGATGCAACCGATCTCCCGGAGGCGGGCGACTTGCCGTACGAGCCGCCGGCGCCCAACGGGCACCCCAACGGCGACGCGCCGCTGTGCTCCGGGCCGGGATGCCCCAACAAGCTCCTCAGTACTGAGGCCAAGGCCGCCGGCAAATGCCGGCCCTGCCGAGGTCGAGCGGCGGCTAGCGCTCGGGACGGCGCCCGATGAGCGGCCACGCGTTGGCTGCTCGGACGTTGCTGGCCGCCGCGGACGAGCTTGTCGGCGGCCCGCCAGTCGAGGCTTCGGCCGCCGCGCTGGCCGGCGACGCCGCGGGCGCATGGCGGACCGCGGCCGTCGAGCTTGCGCGAGCGTTGGTCCGCGCTGTGGCGGAGTCGCACGGCGTCGCGGCCGTTTTGTTCGCCGCGACGGCCGCCGCGGCGGCGGCCGTCGACCGGGGTGATCCGCCGTGAGCCCGCCGAGAGAACCCGACTGTCGGACACCCGGAACACCGTCGATCACATCATTTTCCAGGGAGAAAGGAGCCCATCATTGACCCACAAGCGCACTAAACGCCAGCCAGCCATCGCCGCAGGGCTCAACGCCCCGCGTCGGAATCGCGTTGGGCGGCAACATGGTTGGCCGGCCGACGTTCCGTCCGCCGAGCAGCGCCGCGCCCAACGGCAGCGCGACCTCGAGGCTATCCGCCGAGCGTACGCCGAGATGGTGGCGACATCACACGAAATCGACGACGACACAGCCGAACTGGCGCTGTTGTCGATGCATCTCGACGATGAGCAGCGCCGGCTTGAGGCGGGGATGAAGCTCGGCTGGCATCCGTATCACTTCCCCGACGAACCCGACAGCAAACAGTGAAAACCCGAAACCCGCAGTTAGGGGGGGTGGGTTGCCATCGCCAGCAACCGCCCGACCGGACACCGCCACGGTGGGAGAGCGTGTGCGCGCTCAAGTTTTATGGGGCGTTTTTTGGCATCATGGCATTCGCGACCCGAAACCCGGAAAGAGGAGGGTGGTGTTGAAAATGGGTAGGCGTGGTCCCGCGCCGGCGCCGGCGCAGTTGAAACTCCTCGGCGGCCGCTCGCCGGGCCGTGATTCTGGCGGCCGGCGGGTTACACCACCGGCGGCGTTCGAGCGTGTTGCGCCGGAATGCCCGGATTGGTTGCCGCCAGGCGCTAAAGACATGTGGGGGCGCGTCGTTCCCGAGCTTGCGGCATTAAACCTGCTGAAGGAGTCCGACCTTGGGGTGCTGACCTCCTTCTGCGTCGCCTGGGATCAGCTCATGCAGGCTGTAACAGCCTACCGTGAACAGGGTTTCATCGCGACGAACGCCCGCAGCCGACGGGTGACGGTGCATCCTGCCGTGGCCGCGGCCCGGGCCGCGACGAGGGACGTTTTGGTGCTCGCGCGCGAATTGGGGTGCACGCCAAGCGCTGAGGCGAATTTGGCTGCTGTGCTGGCGGCGGCGGGGGACCCCGACGACGACGAGTTCAACCCGTTCGCCCCAGACCGGTGATGACCTTTTGTGTGTGATACAATCGAGTTTGGCATCTCGGCATCCGCCGACGCCGGGCAGTCGCCGCGGGGCGGCTGGAACCCGGATAGCGGCCGCCATGCGCCACAAGCGATTCCGCGCGTTTCTTGCGTCTGCTAGGCGGTGGCCGAATTTTGAGTAGCATCCTTTTCCGCACGGCCGAGCTGCGGCCTGGTGAGGGCCGCACCGTGTACGGCGTCATCGTGCCTTATGGCGAGGTGACCACCGTCCGCGACCTCGACGGCGAGTTCCGGGAAATGTTCGCTCCTGGCGCTTTTCGGCGCTCCATCGCTGAGCGCGGCCACAAGGTGAAGCTGCTGGTCTCCCACGACGCTCGAACCCGCTACCCGGTTGGCCGGGCCGTCGAGCTGCGTGAGGAGCCTCACGGCTTGTTCGGGGCGTTCGAGCTTGCGAACACCCCGGACGGCGACGAGGCCCTGGCGAATGTGAAAGCTGGTGTGGTGGACGCGTTTTCGGTGGGTTTCCGGCCGATCCGGGACCGCCGGGAAGGGGATGTGATCGTGCGGGTCGAGGCGGCGCTGTTGGAGGTCTCCTTGACCGGCGTTCCGGCCTATCTGGGCGCGCAGATCGCCGGTGTGCGCGCGGAATCGCTTGCAGTCGTTTCCCGTTCGCTAGCCGAAGCCAGGTTAGCCCTGATGGATTGGTAACTCTCTCATGACTAATGAACAACATTTCGCTGACGATGGCGACATCAAACAGCTCAGCCTCGACGAAACCCGTTCCGCGGCAAAACAGCTCCTCGACTCCGTCGAGGGCGACCTGACCGGTGATGTGGCGCAACGTTTTCAGGCGCTGACACGCCACGCCGAGGAACTGCGGGCGGAGCAGCGCCGCCGCGGCCGCGAAGCCGAGGAGGCGCTGCGCCGCTGCCGGGCCGGTGAGCTGAGGGTGGTGCCCGGTGCTCCCACCGGCGGCGACGACGGCGACGCGCCGCCGGGCAACTCGTTGCGCGACACCGCGTTTCGCACACTGGACGTTTGTGTGCGCGATGGCCTGATGTCGTCGCGGGCGGCGGAAGCCGCGGAAACCTTGTGCCGCACCGGGCCGCCGCAGTCGACGTCGTGGGCGCAGCGCTGGCTGGCGGCCACCGGCAACCGCGACTACCTGGGGGCGTTCGTCAAGAGGGTTTCGAACCCTGTTGCGGGGCACACGACCTGGACCGACCGGGAAGCGGCCGCGTGGCGTGAGGCGGCCGCGGTGGCCGCCGAGCAGCGAGCAATGGGCTTGGTGGACACCGCCGGCGGGTTTTTGATCCCGGCGGCGCTGGATCCGGCGATTCTGCTGTCGGGTGATGGTTCAACGAATCCGATCCGGCAGGTGGCGAGGGTGGTGCAAACGACCTCCGAGGTTTGGCGGGGCGTGACCTCCGAAGGCGCCGAGGCTCATTGGTACTCCGAAGCCCAGGAGGTGTCCGACGATTCGCCAACGCTGGCCCAGCCGGCGGTGCCGAGCTACCGTGGCTCCTGCTGGATTCCGTTCAGTCTCGAGATTGAGGGTGACGCCGCCGGATTCGTCGCAGAGGTGGGCCGCGTCCTAGCGGATTCGGTTGAGCAGCTGCAGGCGGCGGCGTTCGTCAGCGGCTCCGGCAACGGCGAGCCCACCGGATTCGTCTCCGCACTGACCGGCACCGCGGACTACACCGTCACCGGCGCGGGGACGGAAGCCGTTGTAGCCGCCGACGTTTACGCGCTGCAGTCGGCGTTGCCGCCGCGCTTTCAATCCAACAGCGCGTTCGCGGCGAACTTGTCCACCATCAACGTGCTGCGCCAGGCGGAAACCGCGAATGGGGCGCTGAAATTCCCATCGCTGCACGCCAGCCCGCCGATGCTGGCCGGGAAACACATCTGGGAGGTGTCGAACATGGACACCGTGGACGCGGCGGTGACCGCCACCAATTACCCGCTGGTGCTTGGCGACTGGAAGCAGTTCATCATCACCGACCGGGTCGGGTCGACGGTGGAGCTGGTGCCGCACGTGTTCGGCGGCAACCGCCGACCGACCGGACAGCGCGGATTCTTCTGCTGGTTCCGAGTCGGTTCTGATGTGCTGGTGGACAATGCGTTCCGCGTGCTGAAGGTGCAGACCACCGCGTAGGTGCCAGGCGTGGGCGGCCCTTTTCGGGTCGTGCGGGCAAAAAGGGAGAACTTTAGCAACCTTTCGGCTCCCAGCGGCCCGCACGGCCCGGAGACTTAGGGGTGCCGGGTCGCCCACGCCGCCAAAAAGAGAACCAAGAGGGTCAAGAGGGGTGATTTTGGGTGGCGAGATCAGTCAACGACTACCGGCGTGAGCTTGAGCGTTGGGTTCGGCAGCAGCAGCGTGTCCAGGATCAGTTCCGGATGGGTGTGCAGCGCGCGATTGAGAGGGAGATTCGGCGTCGCTATGAGGCTTGGCGCCGCCAGGCTGAGCAGGCACGCAAGGCCGCCGAAGATGAGCTGCGCAAGCGTGGACGTGAGCGTCGCCCGTTGGACAAGTTGCCGCCGGGGCCCATCCCGGGCACCGGCGGTCAGCCGCTCCAACCGTTTAAACCATCCCGGTAGCCAGCTTCGCTGCGGGTTGCGTTGTCGATTCGTTTGAGCCGCTGGTAGTGGCCGCGGGAGATGCCGAGGGCTTCGCTGATGGCAGTGTCGGCTTTGTGGGCATCGCGCTCTGATTCTGGCTTAGGCTCCATGGAGCCTAAGCCAGAATATCGAGCCTGGCGGCCATGGTCGCCGCCTTCGCGTTGCCGCTGTTTGGCTTTCGGCCGTTCCAGCTCGGCGATCCGGCGACCAGCGGCGAGCAGCTCCGAGGGGGTGAAATCCTTGCGAAGCGTGTTTTCGGAGCGTTCGGCTTTGGCCCGGTCGACCACGTCGGCGATCGTGTGGCACACGTGCACCGGGATGCGCTCCCATCCGAGCAGCCGTGCAGCCTCGAGCCGCCGCTGGCCGAATACGAGCCGCCTGTCGGGGGTGACGCCGATCGGCTGCAGCAAACGCCAGGGCGACTCACCATGCGGCTGCTGCTGCGGCGCGCACCTCGTCGTCGCACAGCGCTGTGTAGCGTTCTGTTGTCACGATCGAGGCGTGACCGAGAAGTTGTTGTACAGCTCGCAAGTTGTGGGAGCCGCGGTAGGCGCGGGTGGCGTATCGGTGCCGCAGGGTGTGCATGGTCGCGTCACCGGGTAATGCCCGGGAGACGAGTTTTCCCACGTGTTCGGCGGTGAGGTGGCCGCCGGTGCCGTTGGGGAACAGGTAGCCGTGCGGGGTGTCGCGGATGAGCGCGGCCAAGTAGTCGCTGATCGGCACAATACGGCGTTTACCACCTTTGCCGTGAACGAGGAGAAGCCCGCCGTCCATCAAGTCGCCGGTGTGCGCCTGGGCGGCTTCGGCGCGTCGCAGCCCGGCCTCACCGGCTAGGCGGATCATCAGCTCGATTCGACGGTCGGCCTTGGCCAGCGCCGCTTGCCAGACGTCGTCGCCGGCCGGGCGGGGCGGCTGTTTCGGGCAGCGCACCTTAGGCAGGGAGTCTGCGACATAGTCGCGCACCCGGTCCATTTCGTAGGCCCACACGAAGAAGCCCCGCAACGTGCTGCGATAGGTTTTGCGGCCCTCTGGGGAGAGGTGCTGCTGTTTGCCTAGCCAGTCCAGGAGGTGTTCGGCGGTGACGTCGGCGGGTGGGCGGCCGAGGCCGTGGGCGGCTGCGCACAGCACCGTCTTGCGTAGCCGGATCGTCGCTGGGCGTTGACCGGCGGCGTTCAGGTTGAGCAGGTAGTCGTCGATGTCGCGCCGCCAGGATGGCGGGGCGTGGAGGCTCGGCGGCGGACCGGGCGGCTTGTTTTGCGACTTGGCCGCCGCCAGGAAGGCTTCCACCACCCCTAGGTGCCCGACCGCCAGCGTGATCTCGTCGGCGTCACGCAACCTGAAGTGGTGGCCGTTCTTGATTAGTTTCAGATTGAGCCGGTCGGCGCGTTTGCGGGCCAGCCGGACCCGGGTCGCGGTGTTCAC

Protein sequences of DBSCAN-SWA_2

>NC_018078|1430630:1443376|1442377_1443376_-|WP_003900538.1|integrase|DBSCAN-SWA
MNTATRVRLARKRADRLNLKLIKNGHHFRLRDADEITLAVGHLGVVEAFLAAAKSQNKPPGPPPSLHAPPSWRRDIDDYLLNLNAAGQRPATIRLRKTVLCAAAHGLGRPPADVTAEHLLDWLGKQQHLSPEGRKTYRSTLRGFFVWAYEMDRVRDYVADSLPKVRCPKQPPRPAGDDVWQAALAKADRRIELMIRLAGEAGLRRAEAAQAHTGDLMDGGLLLVHGKGGKRRIVPISDYLAALIRDTPHGYLFPNGTGGHLTAEHVGKLVSRALPGDATMHTLRHRYATRAYRGSHNLRAVQQLLGHASIVTTERYTALCDDEVRAAAAAAW
>NC_018078|1430630:1443376|1430630_1431389_-|WP_003413845.1|protease|DBSCAN-SWA
MPEPTPTAYPVRLDELINAIKRVHSDVLDQLSDAVLAAEHLGEIADHLIGHFVDQARRSGASWSDIGKSMGVTKQAAQKRFVPRAEATTLDSNQGFRRFTPRARNAVVAAQNAAHGAASSEITPDHLLLGVLTDPAALATALLQQQEIDIATLRTAVTLPPAVTEPPQPIPFSGPARKVLELTFREALRLGHNYIGTEHLLLALLELEDGDGPLHRSGVDKSRAEADLITTLASLTGANAAGATDAGATDAG
>NC_018078|1430630:1443376|1435975_1436236_+|WP_003899418.1|DBSCAN-SWA
MCAFPSPSLGWTVSHETERPGMADAPPLSRRYITISEAAEYLAVTDRTVRQMIADGRLRGYRSGTRLVRLRRDEVDGAMHPFGGAA
>NC_018078|1430630:1443376|1434466_1435594_+|WP_003899420.1|integrase|DBSCAN-SWA
MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLWSPASGQEDRPGAPFGEYAEGWLKQRGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVGTPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKIRPATLDELETITKAMPDPYQAFVLMAAWLAMRYGELTELRRKDIDLHGEVARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRESLLFPSVNDPNRHLAPSALYRMFYKARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAALRYQHAAKGRDREIAALLSKLAENQEM
>NC_018078|1430630:1443376|1438050_1438296_+|WP_003899415.1|DBSCAN-SWA
MSGHALAARTLLAAADELVGGPPVEASAAALAGDAAGAWRTAAVELARALVRAVAESHGVAAVLFAATAAAAAAVDRGDPP
>NC_018078|1430630:1443376|1441660_1441912_-|WP_003908028.1|DBSCAN-SWA
MERLTAGARDGPRRQLVQRATLTSTLAQLIFGGLACLLSLAAPSLIATPNLPLNRALHTHPELILDTLLLPNPTLKLTPVVVD
>NC_018078|1430630:1443376|1433198_1433432_-|WP_003413717.1|DBSCAN-SWA
MEVRASARKHGINDDAMLHAYRNALRYVELEYHGEVQLLVIGPDQTGRLLELVIPADEPPRIIHANVLRPKFYDYLR
>NC_018078|1430630:1443376|1432933_1433188_-|WP_003413719.1|DBSCAN-SWA
MKHKTDIDEWLDTIEPNPADAHDASHLRRIIAAKEAVQTAESELRAAVNAARAAGDTWAAIGVALGITRQAAFQRFGPHSTASP
>NC_018078|1430630:1443376|1438375_1438699_+|WP_003899414.1|DBSCAN-SWA
MTHKRTKRQPAIAAGLNAPRRNRVGRQHGWPADVPSAEQRRAQRQRDLEAIRRAYAEMVATSHEIDDDTAELALLSMHLDDEQRRLEAGMKLGWHPYHFPDEPDSKQ
>NC_018078|1430630:1443376|1435596_1435959_+|WP_003900543.1|DBSCAN-SWA
MADAVKYVVMCNCDDEPGALIIAWIDDERPAGGHIQMRSNTRFTETQWGRHIEWKLECRACRKYAPISEMTAAAILDGFGAKLHELRTSTIPDADDPSIAEARHVIPFSALCLRLSQLGG
>NC_018078|1430630:1443376|1436626_1438054_+|WP_003899416.1|DBSCAN-SWA
MADIPYGRDYPDPIWCDEDGQPMPPVGAELLDDIRAFLRRFVVYPSDHELIAHTLWIAHCWFMEAWDSTPRIAFLSPEPGSGKSRALEVTEPLVPRPVHAINCTPAYLFRRVADPVGRPTVLYDECDTLFGPKAKEHEEIRGVINAGHRKGAVAGRCVIRGKIVETEELPAYCAVALAGLDDLPDTIMSRSIVVRMRRRAPTEPVEPWRPRVNGPEAEKLHDRLANWAAAINPLESGWPAMPDGVTDRRADVWESLVAVADTAGGHWPKTARATAETDATANRGAKPSIGVLLLRDIRRVFSDRDRMRTSDILTGLNRMEEGPWGSIRRGDPLDARGLATRLGRYGIGPKFQHSGGEPPYKGYSRTQFEDAWSRYLSADDETPEERDLSVSAVSAVSPPVGDPGDATGATDATDLPEAGDLPYEPPAPNGHPNGDAPLCSGPGCPNKLLSTEAKAAGKCRPCRGRAAASARDGAR
>NC_018078|1430630:1443376|1439509_1440043_+|WP_003899412.1|head,protease|DBSCAN-SWA
MSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
>NC_018078|1430630:1443376|1440050_1441490_+|WP_003899411.1|capsid|DBSCAN-SWA
MTNEQHFADDGDIKQLSLDETRSAAKQLLDSVEGDLTGDVAQRFQALTRHAEELRAEQRRRGREAEEALRRCRAGELRVVPGAPTGGDDGDAPPGNSLRDTAFRTLDVCVRDGLMSSRAAEAAETLCRTGPPQSTSWAQRWLAATGNRDYLGAFVKRVSNPVAGHTTWTDREAAAWREAAAVAAEQRAMGLVDTAGGFLIPAALDPAILLSGDGSTNPIRQVARVVQTTSEVWRGVTSEGAEAHWYSEAQEVSDDSPTLAQPAVPSYRGSCWIPFSLEIEGDAAGFVAEVGRVLADSVEQLQAAAFVSGSGNGEPTGFVSALTGTADYTVTGAGTEAVVAADVYALQSALPPRFQSNSAFAANLSTINVLRQAETANGALKFPSLHASPPMLAGKHIWEVSNMDTVDAAVTATNYPLVLGDWKQFIITDRVGSTVELVPHVFGGNRRPTGQRGFFCWFRVGSDVLVDNAFRVLKVQTTA
>NC_018078|1430630:1443376|1441899_1442364_-|WP_003900539.1|DBSCAN-SWA
MLQPIGVTPDRRLVFGQRRLEAARLLGWERIPVHVCHTIADVVDRAKAERSENTLRKDFTPSELLAAGRRIAELERPKAKQRQREGGDHGRQARYSGLGSMEPKPESERDAHKADTAISEALGISRGHYQRLKRIDNATRSEAGYRDGLNGWSG
>NC_018078|1430630:1443376|1433530_1433803_-|WP_003900544.1|DBSCAN-SWA
MDDLTRLRRELLDRFDVRDFTDWPPASLRALIATYDPWIDMTASPPQPVSPGGPRLRLVRLTTNPSARAAPIGNGGDSSVCAGEKQCRPP
>NC_018078|1430630:1443376|1436232_1436625_+|WP_003899417.1|DBSCAN-SWA
MTAVGGSPPTRRCPATEDRAPATVATPSSTDPTASRAVSWWSVHEYVAPTLAAAVEWPMAGTPAWCDLDDTDPVKWAAICDAARHWALRVETCQAASAEASRDVSAAADWPAVSREIQRRRDAYIRRVVV
>NC_018078|1430630:1443376|1432304_1432586_-|WP_003899423.1|DBSCAN-SWA
MIVVRTAEAAEQALTEGQLVCPRRGCGDTLRRWRYGRRRHVRSLGSQVIDVRPQRVRCRRCESTHVLLPAALQPRLGRGGGGQLRPGVWCTGR
>NC_018078|1430630:1443376|1434094_1434322_+|WP_003899421.1|DBSCAN-SWA
MIAGVDQALAATGQASQRAAGASGGVTVGVGVGTEQRNLSVVAPSQFTFSSRSPDFVDETAGQSWCAILGLNQFH
>NC_018078|1430630:1443376|1433708_1434098_+|WP_003899422.1|DBSCAN-SWA
MRARSDAGGQSVKSRTSNRSRSSRRSRVRSSISALVDNPQARPRELPVLCGWPVVRVEPVCEFVPEPVCGQAEVLGEPAAAHRVTSARRSPSTTVCSRSQKASAVVISSVSSVARVRRASVSSVDATTA
>NC_018078|1430630:1443376|1438730_1439357_+|WP_003899413.1|terminase|DBSCAN-SWA
MPSPATARPDTATVGERVRAQVLWGVFWHHGIRDPKPGKRRVVLKMGRRGPAPAPAQLKLLGGRSPGRDSGGRRVTPPAAFERVAPECPDWLPPGAKDMWGRVVPELAALNLLKESDLGVLTSFCVAWDQLMQAVTAYREQGFIATNARSRRVTVHPAVAAARAATRDVLVLARELGCTPSAEANLAAVLAAAGDPDDDEFNPFAPDR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003413845.1|1430630_1431389_-|protease	ATP-dependent Clp protease ATP-binding subunit	A0A249XSS8	Mycobacterium_phage	4.7e-16	40.8
WP_003899423.1|1432304_1432586_-	hypothetical protein	NA	NA	NA	NA
WP_003413719.1|1432933_1433188_-	hypothetical protein	NA	NA	NA	NA
WP_003413717.1|1433198_1433432_-	hypothetical protein	NA	NA	NA	NA
WP_003900544.1|1433530_1433803_-	hypothetical protein	NA	NA	NA	NA
WP_003899422.1|1433708_1434098_+	hypothetical protein	NA	NA	NA	NA
WP_003899421.1|1434094_1434322_+	hypothetical protein	NA	NA	NA	NA
1434287:1434314	attL	NA	NA	NA	NA
WP_003899420.1|1434466_1435594_+|integrase	site-specific integrase	A0A1X9SFC1	Mycobacterium_phage	1.5e-66	40.4
WP_003900543.1|1435596_1435959_+	hypothetical protein	NA	NA	NA	NA
WP_003899418.1|1435975_1436236_+	helix-turn-helix domain-containing protein	A0A2P1CHK7	Mycobacterium_phage	3.0e-15	64.6
WP_003899417.1|1436232_1436625_+	DUF2742 domain-containing protein	NA	NA	NA	NA
WP_003899416.1|1436626_1438054_+	DUF3631 domain-containing protein	NA	NA	NA	NA
WP_003899415.1|1438050_1438296_+	type II toxin-antitoxin system antitoxin	NA	NA	NA	NA
WP_003899414.1|1438375_1438699_+	type II toxin-antitoxin system toxin	NA	NA	NA	NA
WP_003899413.1|1438730_1439357_+|terminase	phage terminase small subunit P27 family	V9H0V4	Actinophage	1.6e-17	47.2
WP_003899412.1|1439509_1440043_+|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	3.1e-06	32.9
WP_003899411.1|1440050_1441490_+|capsid	phage major capsid protein	A0A1B3AYS4	Gordonia_phage	1.4e-66	40.6
WP_003908028.1|1441660_1441912_-	hypothetical protein	NA	NA	NA	NA
WP_003900539.1|1441899_1442364_-	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_003900538.1|1442377_1443376_-|integrase	tyrosine-type recombinase/integrase	A0A2D1G8E2	Mycobacterium_phage	7.4e-62	47.8
1443911:1443938	attR	NA	NA	NA	NA