CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018422	Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence	3 crisprs	NA	0	4	0	0
NC_018286	Phaeobacter inhibens 2.10, complete sequence	0 crisprs	cas3,WYL,csa3,casR,DEDDh	0	0	1	0
NC_018421	Phaeobacter inhibens 2.10 plasmid pPGA2_239, complete sequence	0 crisprs	NA	0	0	0	0
NC_018423	Phaeobacter inhibens 2.10 plasmid pPGA2_95, complete sequence	0 crisprs	csa3	0	0	0	0

1. NC_018422

CRISPR-Cas detection and classification

Crispr_ID: NC_018422_1

• CRISPR_ID: NC_018422_1
• CRISPR_location: 53032-53109
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018422_1

Consensus_repeat	Method
GGTGGTGAAGGCAACGACATCCT	CRISPRCasFinder

spacers of NC_018422_1

>1.1|53055|31|NC_018422|CRISPRCasFinder
GAATGGCCTTGGCGATGTTGACACCCTGGTC

CRISPR arrays and Neighbor proteins around NC_018422_1

CRISPR arrays

The CRISPR arrays of NC_018422_1

>merge|NC_018422|1|53032-53109|CRISPRCasFinder
GGCGGCGATGGCAACGACATGCTGAATGGCCTTGGCGATGTTGACACCCTGGTCGGTGGCGCAGGCGACGACACCCTG

>NC_018422|1|1|53032-53109|CRISPRCasFinder
GGCGGCGATGGCAACGACATGCT	GAATGGCCTTGGCGATGTTGACACCCTGGTC
GGTGGCGCAGGCGACGACACCCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224596
NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902
NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl|CDD|226969
NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase	unknown	unknown	gnl|CDD|223636
NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein	unknown	unknown	gnl|CDD|371324
NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter	unknown	unknown	gnl|CDD|226055
NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase	unknown	unknown	gnl|CDD|133028
NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|273648
NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213187
NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|224014
NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187563
NC_018422.1|WP_014889415.1|57705_59013_-|hypothetical-protein	unknown	unknown	unknown
NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase	unknown	unknown	gnl|CDD|133028
NC_018422.1|WP_014889412.1|54033_55053_-|hypothetical-protein	unknown	unknown	unknown
NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein	unknown	unknown	gnl|CDD|367564
NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein	unknown	unknown	gnl|CDD|380205
NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase	unknown	unknown	gnl|CDD|369942
NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl|CDD|376414

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease	gnl|CDD|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	6.0012e-33
NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	1.21351e-92
NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase	gnl|CDD|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.91224e-171
NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase	gnl|CDD|223636	COG0562, Glf, UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane].	0
NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein	gnl|CDD|371324	pfam10983, DUF2793, Protein of unknown function (DUF2793). This is a bacterial family of proteins with unknown function.	1.12348e-37
NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase	gnl|CDD|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.97558e-95
NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl|CDD|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213187	cd03220, ABC_KpsT_Wzt, ATP-binding cassette component of polysaccharide transport system. The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.	7.74672e-87
NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase	gnl|CDD|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187563	cd05253, UDP_GE_SDE_e, UDP glucuronic acid epimerase, extended (e) SDRs. This subgroup contains UDP-D-glucuronic acid 4-epimerase, an extended SDR, which catalyzes the conversion of UDP-alpha-D-glucuronic acid to UDP-alpha-D-galacturonic acid. This group has the SDR's canonical catalytic tetrad and the TGxxGxxG NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.4863e-174
NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter	gnl|CDD|226055	COG3524, KpsE, Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane].	1.14417e-63
NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase	gnl|CDD|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.15755e-58
NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein	gnl|CDD|367564	pfam03567, Sulfotransfer_2, Sulfotransferase family. This family includes a variety of sulfotransferase enzymes. Chondroitin 6-sulfotransferase catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine residue of chondroitin. This family also includes Heparan sulfate 2-O-sulfotransferase (HS2ST) and Heparan sulfate 6-sulfotransferase (HS6ST). Heparan sulfate (HS) is a co-receptor for a number of growth factors, morphogens, and adhesion proteins. HS biosynthetic modifications may determine the strength and outcome of HS-ligand interactions. Mice that lack HS2ST undergo developmental failure only after midgestation,the most dramatic effect being the complete failure of kidney development. Heparan sulphate 6- O -sulfotransferase (HS6ST) catalyzes the transfer of sulphate from adenosine 3'-phosphate, 5'-phosphosulphate to the 6th position of the N -sulphoglucosamine residue in heparan sulphate.	0.00667548
NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.92398e-22
NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	6.9571e-23
NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase	gnl|CDD|369942	pfam08548, Peptidase_M10_C, Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.	8.15701e-21
NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl|CDD|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	7.87907e-101

Protein sequences

>NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein
MSQVSSQTSGSRTVAETAFEARFSPRLVAAETYHDSNDVILFMHIPKTAGMSVGKALQAAFDIFHPVSWENTNQSFRNKTRKALYRRSDEATPCRQVLMGHFAWSDVMYWRHQELPLKCATIIRDPLDRFVSNYRYNTSDKHPQHEAFAARYPTLESYAHVLPLDYQLSLMTGAFYSFDHALEKLNRYYSFIGVTEHLGASLQHFRRSHGLAELTEHRENTGSKAKAAEDIPDAVRNIVGEKSRNDARLHQLVSRCYG
>NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase
MARTSAQHSGSAHKPGLGEIRKARKGNRGAFWLIGVFSFFANLLMLTSPLYMMQVYDRVLGSRSLETLVALTVLAGFLFLIMGVLDYVRGRILARVGARFHDQLETRVFNAVQDKSAAGFNDDIAKVGLRDLEAMQKALSSPIVSAFFDLPWTPLFLGLIAVFHPLLGLLALIGGAVLVVFALANQMISKAAVENASMMAASAHQVSDGMRNNAELIQGLGMRRAAFAKWRMLRSQAVGSELSAADMTGGFSTATRTFRLALQSAMLGTGAYLVLTEGLTPGVMIASSIIMGRALAPIETLIGQWALVQRAMQAQERLAQMLTETPERPAPMKLARPAAKLEVQGVALVPPVAPGQVAKPALQGLNFSIQPGQALGVIGASGAGKSSLARALIGVWHPVSGKIRLDGAALNQYDMDDLGSYIGYLPQQVTLFDGTIAENIARLSMMPDPDQVVAAARKAAVHDMILQLPQGYDTPVRVASNRLSGGQVQRIGLARALYGDPVLLVLDEPNSNLDNEGSQALNLAVSHAKKDGRAVIIMAHRPAAIQLCDLILILDNGTQRAFGPRDAVLGEHLQNPQVVQKKQAQQQAAAPSTSAPSTPTQKQPAPKQAAPKQAEAKS
>NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MSDTSKSYPIRGLTIAGLLAMGLLVGGLGQWAATAEISGAVIASGSIKVEQNRQVVQHPYGGVVDEVLVSEGDLVEEDALLLRLEPSELLAERQIVEGQLAETLARRSRYSAERDEAEEVTFAELLFELSGTHVQTEELINGQKRLFEARLVNLRARISRLQERIGQIQSQIDGIEAQQSALQEQLVLIGQELENQQSLLSQGLAQSSRVLSLQREQSRLRGQAGALTAQKAQAEGQVTELGLEILNQRSARREEAITTLRDLQVRELELIERRNLILQRLSRLEVRAPVSGLVYDLNVFARKSVIRAADPLMYLIPQSQPLVISAQVAPSDIDQVYLNQPVSLNFSSFNQRTTPTLFGTVSTVSADSFVDPQTGRSYYVVEARLNKGEIDRLPEGNVLVPGMPVETFIQTNSRTPFAYLLQPFTDYLNRAFRES
>NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase
MKKALITGVTGQDGSYLAEFLLEKGYEVHGLKRRASSFNTQRVDHIYQDPHTDHARFKLHYGDLTDTSNLTRLLSEIEPDEVYNLGAQSHVAVSFEAPEYTADVDGIGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQETPQRETTPFYPRSPYAVAKLYSYWITVNYREAYGIYACNGILFNHESPRRGETFVTRKITRGLANIAQGLEECLYMGNIDALRDWGHARDYVRMQWMMLQQEVPEDFVIATGKQYSVRQFITWSAQELGLTLAFSGEGVEEIATVTAIEGDMAPALKVGDVVLRIDPRYFRPAEVETLLGDPTKAKQKLGWVPEITTEEMCAEMVREDLKTARRHALLKEHGMDLPVSTEG
>NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase
MGTSTVKIYVAGHRGMVGGAILRRLQARRAAGEDIQLITRTSAELDLTDQAMVQAFFAAERPDQVVLAAAKVGGIHANNAYPAQFIYENLMMECNVIHAAHQQGVERLLQLGSSCIYPKHAPQPMAEAALLSDVLEATNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPGDNFHPENSHVLPALIRRFDAAARAGEDHVTIWGTGTPRREFLHVDDMAAASLFVLDLDPATYRRETSPMLSHINVGCGQDISILELAQMVAGVVGFDGEIRTNPEQPDGTPRKLMDVSRLARLGWQAEIALRDGIAQTYEWYLQQDPERLRSK
>NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MITPILLCGGSGTRLWPLSRKSYPKQFVPLVGETTLFQASALRLSGEGFAAPMVLTNSDFRFIVTEQLAEAGIDPGAILIEPAGRNTAPAVLAAALWLRARDPDGLMLVAPSDHVVPDAAAFRAAVAAAEPAARAGELVTFGIKPDRAETGYGYLELDGDPGDFSPKVIGLKRFVEKPDLATAEDMLASGQFLWNAGIFLFSVKAIIAAFETHAPDLMVPVQGAVDQGEPDLGFLRLDPAAWDGAADISIDYAVMERAENLAVVPYAGGWSDLGGWDAVWRESGPDGDGIVTQGRATAIECSNSLLRSEDDGLEVVGIGLKDVIAVAMPDAVLVADASRAQEVKKAVAALKAKSARQAEAFPKDHRPWGWFESLVVGERFQVKRIHVHPGAALSLQSHHHRSEHWIVVEGTAKVTVDDSVQLVSENQSVYIPLGAVHRMENPGKVPMVLIEVQTGSYLGEDDIIRYEDIYARK
>NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein
MSDPLSETTPRLALPYLMPAQAQKHVTHNEALRMLDALVQLRLEGFDATTPPTTPTEGAAYGLADSPTDAWAGQGGRLAIWQDAAWQFLTPQPGWRAWVPADQALRVWDGTQWQLPPLSGDRLDRLGIATDADASNRLSLRSPASLLSHDGGGHQLKINKASGSDTASLLFQSNWAGHAEMGLAGNTDFTVKLSPDGSSWDAAMVLKSANGRAGFGTYDPGARLEVSGDDSTLLALTATGSSQDYLTAGDGSGAMFRLSQTGNGYCDGAWTGGGADYAEFFEWEDGNPDGEDRRGVSVVMAGDRIRAAQPGEAPIGVISTTPSILGNDDGGRWQGRSLRDGFGAMLREAGGAPCLNPAYDPTRPYRSRAERAEWDMVGLLGRLRLRTGQPTDPRWIRLRALRPGKNTPPEGLEDWLIR
>NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein
MTQRGSSRMDLQFAGRFGANDQLLDSDLRDLEIHQGANGALQLFAVSGLNGGIASYGLGRGAPVLRDSLYHRALGLAGGEATLAEIGGETRLLVEGSTRSALAFHLIGGNGQLSAQQQASLPGAGAAGLAATVAGDLSGGGSVVYGLANGQLSGWQLSAGGPPGAEVATRGAAAAYARPGAVALELADLGGGAQVLLLADRMEQGIQSYRVDPDNGALSVADSLGAADGLGLAEPTAVESFTAFGSSWAVVAAAGSGSLSLIALGRDGQMSLSDHVLDTAATRFGGATALEVVEVAGEMLVLAAGSDDGLALFRILPEGQLVHVTSLAHASGTEDAGLGLENVTALAAAVVGGDLQIFASSGRAEGLSQFTLSLAELGDVITTDGGRISGTGAADVLAGGIGAVLSGGAGADVFVLRPAEEGRSGSLRITDFEAGQDSLDLSEFDGLRSLEGLQIRSRSDGAVITHQAADGSRTEVVVQSRDGGSLETADLFADGFVFADRMLPPAEAPDPIRYGSGGADRITARSAGDQINGLEGNDTLLGGDGRDSLWGDDGHDRLIGGKGVDRLRGQAGNDVLLGQDARDLLVGGAGRDTLDGGRGGDRLLGGADADLLRGGGENDLLRGGAQGDRLLGQSGRDKLFGQKGNDLLDGGGGHDTLTGGAGADVFVFGAGHGSDRIRDFTQGEDVLHLGRLARAGIAEDMGDLTLQQQGDHTLILTGAGDILLLNQTAAELSADDFIF
>NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase
MPTYQDYRALLVDGADGWHEGSEVIRYHFLTSVPDYYDYDPDFGDYDVGGEYLPEGATVNMDPAERQMMLQAVAAWNEVANLNLIPARGGTADLTFASAHFADAGLFGFIADFPDPSDLGTRPSPAGDLWLNNSNPDQYVPGIGPILGHTSWNTYLHELGHALGLHHPNEMPENPTTPGQFTVMSYLPHPGEADLDQDLQGWALTPMLWDMQALQALYGANTETRTDATSYFGDGDGRGDQAYQYGADDMTVQGGDGVARNVSLTIWDAGGQDLIDASDVAGNSRIDLRPGQYSTIGALENNVAMAAAVRVDGRTLNLIEDAWGGAGNDHLTGNGAANELAGNAGRDTLAGARNSDVLIGGQGSDRLQGGKGHDALEGGRGRDTLKGGAGQDTLDGGDGNDRMAGGRGADVFVFSQGADVVIDFQSNDRIDMRATTGVSDFADLRDDHLEVRGADLVIRDDNGWSLTLQDTAFDVLRADDFLF
>NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase
MQIEDTDLPGVKILTPARFGDARGFFCESWNKARMAEAGLDFDFVQDNHSLSMEVGTLRGLHFQAPPHAQAKLVRCGQGALFDVAVDIRKGSPTYGRWTGVELSAANGRQLLIPAGFLHGFITRSPGTEVLYKCDAYYAPDCDGGVAWDSCGIDWGFDGTPVLSEKDAAAPRFEDLDSPFVWEG
>NC_018422.1|WP_014889412.1|54033_55053_-|hypothetical-protein
MTRRLWLHIGSHKTGSTSLQTALRQGQSDKTLGGWSYLHARPRVDFNPLVRCHGMGAGMHTELRWPFLERRMADADHRGHGDCILSSEMLFWLMDVADLEALRQQLRAHFDEISVVAYLRRQDALALSHRKQVVMGRAAYQFYGAQIRGLPEFQPHMMRYFDYATKLARWEQVFGAGNVTVRRFQRSDLVGGDTVLDFYHLVGLTPPPELPQENAAWSRSQLLAGLWLRQRGYPRQSFAEAVQELPDDGRLMPARAEAAAFLARFEAINRALAARYDPQGPEMFFDCDLSRYPEQGNGEGLAGDAVVTPEVLAELESRARAEMAARELPLDALNPDDRL
>NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein
MSQDRDYIDQEITQIRFIYETLYPETPVETHMWWEKAKLPTPAVQPQDMSYGAEMMALTYIGNLRTGPQETPALPGKRVFVTIPSPRQVAVRESAGGVPWHKRPRKYRAIHALSPILAEQMKYQIEARRWRKLPARHKFSRLACSRGIFETQKMAPEGRHGGKDPAILIGLHWLDVGGAESLGIDSIQWALDAGLRVFVMVGQEGPERLLAKLPEDPRLQLIRTDRYLPRSQTSAFVSQLIAQENIILTHNHHCVPLYDALPTIKLRHPHVVNIDSTHIVEYADGGYPRISGVWSNFIDHHHVISSDLERFYKERFRVYGSKLVLGRLLDDSRRGAEVAPVRIKAGQKRCRVAFVGRMVHQKRPVVALSIIRRLRAWGKRNGVDFRFDMVGEGPYRGAVEHLLTRYRLADVVHLHPAGTDVPALLGDSDILLVPSSNEGLALVCYEAIEAGCVPICSDVGAQAEICPPETLVAWSPLQAVRDSVAVVQRLLREEGFAETVEAGQRARMQALQADPSAREVLDRLYRDALAAVAAEQPLPKEAATRRKTKSKAPA
>NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase
MNIRSSLAAVIVTYNRLDKLKRVIAALQAQTCLPERVFVIDNASTDETGSWLTQLQKDDPRFQHVRLPENIGGAGGFYEGARVAYEEGYDFIWFSDDDAYPDPNAIELLLTGIKDFEARFTWRPSFACSAVKWTNGDLCEMNTPSTVWDWPRFYSPETPYFLVGSCSFVSVLVPRWAIQKHGFPIKEYFIWYDDAEYTQRIAKSYPGIYCPNSVVVHDVPENKGVNYSLVNQANIWKFRYGARNEASFRRREQGWAGVAVFARGVRRQMRQGNVEKSLRREVYKAIWRGCSFNPQIIRPDPDTGV
>NC_018422.1|WP_014889415.1|57705_59013_-|hypothetical-protein
MEPMSDKTGARPKTLVIHIGDHKTGTTTIQNALAVGSIQLHDAKLLYPAKMNHNYLTGFITSYRKGTPLPKHLEDRDGLTEVAAQIAASDADYAVLSAEAFENIPAPEFHDLVETFFRGCADRIHIVAYVRPHAQRILSSYAEQIKIGWYRGSMQEFFDHNLQNGRFHYAPRFAQWRELFGDEFTLRPMIRKELKNGSVLDDFAEVAFDGRPCTVEEFEPENQAMTVRELALMYFLQGQFQEQDPWLRHTLGWELSRQLDRSRGDSEAKVRKLVMARDLAEAATAAYRCDAEVMDATFFEGRPLMQTALRDMEKQSAPCAPSLDPSQFFSPEHLRNLTVMAKIIEGMLERQGKWPSYFHSHRIKDIERHKNARLGLDENGDPLEPEAEMPAGSETAATPAPQSAVTISDTPAQTPPPARVLADAAAGAAPQKDQP
>NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase
MVGAGLSGAVIGRHLAEAGHKITVLDSRDHIGGNCHTERDAETGVMVHVYGPHIFHTDDAEVWDYVNGFETFLPYKNRVKTTSLDPEGRRGVFSLPVNLHTINQFFGKTLRPEEAHDFITEEQADTSITDPQTFEEQALRFVGRDLYEAFFKGYTIKQWGVAPSALPASILKRLPVRFNYDDNYFFHKYQGMPENGYTAMIEKILDHPGITVKLETVFDQSQAADYDHVFYSGPLDGYFNYQLGRLGYRTLDFERFTHQGDYQGCAVMNYGEEAVPYTRITEHKHFAPWESHDGSVCYREFSRAAEPEDIPYYPIRQVEEKALLGEYVALAEQAEGVTFVGRLGTYRYLDMDVTIREALDTARGFLAAQENRAPVPAFFVAPL
>NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein
MIRFENLTKSFWLKGERRIVIDNLNLTLPTGRSLALLGRNGAGKSTLLQLVAGTMRPDHGEIISDGSISWPVGLAASFHGDLSGAENVRFIARIYGVDTDDLVGFVEDFAELGKFYHMPMRSYSSGMRARLTFGASMGIKFDTYLVDEVTAVGDAAFKRKSRDIFTDRMRHSSAILVNHSMRQLRQFCNAGLVLDNGRLRYFSDLDEAIAEHHRLMAV
>NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter
MTQTPPSSLTGRPASEEATSEEAAAADTAASTATGTPAASPAATASDSAPDAAEAAAPAQRVPDPVKQLKRVRRKARKAEAAVAELEARIAEAEQRPAYPLARPASMKKRHWGLVISFVALVLAPLLAVMIYLWTFAEDQYASTAGFTVRSQESSGANDLLGGLAQFAGTSSASDSDILYEFIQSQEMVAAVDAAVDLQGHYSALWPRDWVFALWPEASLEDLTWYWQRIVGISFDSGSGLIEVQALAFDAATAQAITKAIVAESQTRINALNEQARADAMRYARADLDEALERLKDARQSLTSFRTRTRIVDPEADIQGRMGVMNNLQQQLAEALIQYDLLRGTVTAADPRLTKAQQHIDVIRDRINIERQTFTSNNTDTGGVGEDYPSLIAEFERLTVDREYAEESYRAALTALEVARDDAARQSRYLATYINPTRATEPEYPRRAVLAALAGLFLLLTWSILALIYYSIRDRS
>NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease
MASLSSSAPPAQPRPLSPPKTQVTAQAPAQTPAQIPASPAANPHHRHRRSMATLRTVAALVLREMSTRYGRTPGGYLWGILEPLAAILFLSLGFSLVIRTPSLGTSFLLFYATGFLPFNLYQTLSGTVARALAYSRPLLRYPAVTWLDAILARFVLNSLTGIVITTLLITGILAVIDSRTAIDLPPLVEAITLAMVLGLGVGCINAVLMGLFPLWDVAWSIITRPLFLASGVIYIYEDLPPVAQDVLWYNPLLHITGLMRTGFYPTYNADYVSHAYVLLIGMTLTALGLILMRRYHRVILNR
>NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase
MNETLIPEPALQADMQQAGAGRLVAVVVTYNRLAKLKVTLARLLGSPAQELASLVVVDNASNDGTGDWLAGWAAEHPRVDVVTSTTNQGGAGGFALGMQRAMEAHTPDWLVVMDDDGRPEPGGLAAFHAMGQSGALAHWDAVAAAVYFPSGEICEMNRPSRNPFWSLSHFLSTARKGRDGFHIPRRAYDGGLSAIDVTSFVGFFISAAAVRRVGYPDPKLFIYGDDALYTLGLSAAGGRICFAADVRFEHDFSTFSNGDSGQRFRPLWKVYYHHRNLLLLYRQAAGWLFWPVLLLILPKWILKVRHHPGVRRAYLRLTWLAVRDGLLRRLGRSHGEVLAEARE
>NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein
MKTALITGSAGFIGYHLADRLLAAGWRVIGLDCLSPYYDVRLKECRHARLAEHPGFMPIIGKLEDPDRLMGLFATHKPDAVIHLAAQAGVRHSIDAPRDYLEANLIGTFELLEAARAHPPAHMLIASTSSAYGANTQMPFDERQQADHQMSFYAATKKAGETMAHSYAHLYGLPTTMFRFFTVYGPWGRPDMALFKFTKAMQAGQPIDVYNHGRMSRDFTYIDDLVAGITGLIDAVPGDQPVSEQDNLSPVAPFRVVNIGASRPTPLMDYIAALETALGITAQKNLMEMQAGDVPATWADTSLLSQLTGYEPQVPVEEGVARFVTWYRAYYGDAQG

Crispr_ID: NC_018422_2

• CRISPR_ID: NC_018422_2
• CRISPR_location: 53200-53277
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_018422_2

Consensus_repeat	Method
GGTGGTGAAGGCAACGACATCCT	CRISPRCasFinder

spacers of NC_018422_2

>2.1|53223|31|NC_018422|CRISPRCasFinder
CGACGGTGGTGAAGGCAACGACATCCTGCGT

CRISPR arrays and Neighbor proteins around NC_018422_2

CRISPR arrays

The CRISPR arrays of NC_018422_2

>merge|NC_018422|2|53200-53277|CRISPRCasFinder
GGCGAAGCGGGCAACGACAACATCGACGGTGGTGAAGGCAACGACATCCTGCGTGGCGGTGGTGACGATGACAACCTG

>NC_018422|2|2|53200-53277|CRISPRCasFinder
GGCGAAGCGGGCAACGACAACAT	CGACGGTGGTGAAGGCAACGACATCCTGCGT
GGCGGTGGTGACGATGACAACCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224596
NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902
NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl|CDD|226969
NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase	unknown	unknown	gnl|CDD|223636
NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein	unknown	unknown	gnl|CDD|371324
NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter	unknown	unknown	gnl|CDD|226055
NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase	unknown	unknown	gnl|CDD|133028
NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|273648
NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213187
NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|224014
NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187563
NC_018422.1|WP_014889415.1|57705_59013_-|hypothetical-protein	unknown	unknown	unknown
NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase	unknown	unknown	gnl|CDD|133028
NC_018422.1|WP_014889412.1|54033_55053_-|hypothetical-protein	unknown	unknown	unknown
NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein	unknown	unknown	gnl|CDD|367564
NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein	unknown	unknown	gnl|CDD|380205
NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase	unknown	unknown	gnl|CDD|369942
NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl|CDD|376414

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease	gnl|CDD|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	6.0012e-33
NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	1.21351e-92
NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase	gnl|CDD|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.91224e-171
NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase	gnl|CDD|223636	COG0562, Glf, UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane].	0
NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein	gnl|CDD|371324	pfam10983, DUF2793, Protein of unknown function (DUF2793). This is a bacterial family of proteins with unknown function.	1.12348e-37
NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase	gnl|CDD|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.97558e-95
NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl|CDD|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213187	cd03220, ABC_KpsT_Wzt, ATP-binding cassette component of polysaccharide transport system. The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.	7.74672e-87
NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase	gnl|CDD|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187563	cd05253, UDP_GE_SDE_e, UDP glucuronic acid epimerase, extended (e) SDRs. This subgroup contains UDP-D-glucuronic acid 4-epimerase, an extended SDR, which catalyzes the conversion of UDP-alpha-D-glucuronic acid to UDP-alpha-D-galacturonic acid. This group has the SDR's canonical catalytic tetrad and the TGxxGxxG NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.4863e-174
NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter	gnl|CDD|226055	COG3524, KpsE, Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane].	1.14417e-63
NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase	gnl|CDD|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.15755e-58
NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein	gnl|CDD|367564	pfam03567, Sulfotransfer_2, Sulfotransferase family. This family includes a variety of sulfotransferase enzymes. Chondroitin 6-sulfotransferase catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine residue of chondroitin. This family also includes Heparan sulfate 2-O-sulfotransferase (HS2ST) and Heparan sulfate 6-sulfotransferase (HS6ST). Heparan sulfate (HS) is a co-receptor for a number of growth factors, morphogens, and adhesion proteins. HS biosynthetic modifications may determine the strength and outcome of HS-ligand interactions. Mice that lack HS2ST undergo developmental failure only after midgestation,the most dramatic effect being the complete failure of kidney development. Heparan sulphate 6- O -sulfotransferase (HS6ST) catalyzes the transfer of sulphate from adenosine 3'-phosphate, 5'-phosphosulphate to the 6th position of the N -sulphoglucosamine residue in heparan sulphate.	0.00667548
NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.92398e-22
NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	6.9571e-23
NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase	gnl|CDD|369942	pfam08548, Peptidase_M10_C, Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.	8.15701e-21
NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl|CDD|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	7.87907e-101

Protein sequences

>NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein
MSQVSSQTSGSRTVAETAFEARFSPRLVAAETYHDSNDVILFMHIPKTAGMSVGKALQAAFDIFHPVSWENTNQSFRNKTRKALYRRSDEATPCRQVLMGHFAWSDVMYWRHQELPLKCATIIRDPLDRFVSNYRYNTSDKHPQHEAFAARYPTLESYAHVLPLDYQLSLMTGAFYSFDHALEKLNRYYSFIGVTEHLGASLQHFRRSHGLAELTEHRENTGSKAKAAEDIPDAVRNIVGEKSRNDARLHQLVSRCYG
>NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase
MARTSAQHSGSAHKPGLGEIRKARKGNRGAFWLIGVFSFFANLLMLTSPLYMMQVYDRVLGSRSLETLVALTVLAGFLFLIMGVLDYVRGRILARVGARFHDQLETRVFNAVQDKSAAGFNDDIAKVGLRDLEAMQKALSSPIVSAFFDLPWTPLFLGLIAVFHPLLGLLALIGGAVLVVFALANQMISKAAVENASMMAASAHQVSDGMRNNAELIQGLGMRRAAFAKWRMLRSQAVGSELSAADMTGGFSTATRTFRLALQSAMLGTGAYLVLTEGLTPGVMIASSIIMGRALAPIETLIGQWALVQRAMQAQERLAQMLTETPERPAPMKLARPAAKLEVQGVALVPPVAPGQVAKPALQGLNFSIQPGQALGVIGASGAGKSSLARALIGVWHPVSGKIRLDGAALNQYDMDDLGSYIGYLPQQVTLFDGTIAENIARLSMMPDPDQVVAAARKAAVHDMILQLPQGYDTPVRVASNRLSGGQVQRIGLARALYGDPVLLVLDEPNSNLDNEGSQALNLAVSHAKKDGRAVIIMAHRPAAIQLCDLILILDNGTQRAFGPRDAVLGEHLQNPQVVQKKQAQQQAAAPSTSAPSTPTQKQPAPKQAAPKQAEAKS
>NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MSDTSKSYPIRGLTIAGLLAMGLLVGGLGQWAATAEISGAVIASGSIKVEQNRQVVQHPYGGVVDEVLVSEGDLVEEDALLLRLEPSELLAERQIVEGQLAETLARRSRYSAERDEAEEVTFAELLFELSGTHVQTEELINGQKRLFEARLVNLRARISRLQERIGQIQSQIDGIEAQQSALQEQLVLIGQELENQQSLLSQGLAQSSRVLSLQREQSRLRGQAGALTAQKAQAEGQVTELGLEILNQRSARREEAITTLRDLQVRELELIERRNLILQRLSRLEVRAPVSGLVYDLNVFARKSVIRAADPLMYLIPQSQPLVISAQVAPSDIDQVYLNQPVSLNFSSFNQRTTPTLFGTVSTVSADSFVDPQTGRSYYVVEARLNKGEIDRLPEGNVLVPGMPVETFIQTNSRTPFAYLLQPFTDYLNRAFRES
>NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase
MKKALITGVTGQDGSYLAEFLLEKGYEVHGLKRRASSFNTQRVDHIYQDPHTDHARFKLHYGDLTDTSNLTRLLSEIEPDEVYNLGAQSHVAVSFEAPEYTADVDGIGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQETPQRETTPFYPRSPYAVAKLYSYWITVNYREAYGIYACNGILFNHESPRRGETFVTRKITRGLANIAQGLEECLYMGNIDALRDWGHARDYVRMQWMMLQQEVPEDFVIATGKQYSVRQFITWSAQELGLTLAFSGEGVEEIATVTAIEGDMAPALKVGDVVLRIDPRYFRPAEVETLLGDPTKAKQKLGWVPEITTEEMCAEMVREDLKTARRHALLKEHGMDLPVSTEG
>NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase
MGTSTVKIYVAGHRGMVGGAILRRLQARRAAGEDIQLITRTSAELDLTDQAMVQAFFAAERPDQVVLAAAKVGGIHANNAYPAQFIYENLMMECNVIHAAHQQGVERLLQLGSSCIYPKHAPQPMAEAALLSDVLEATNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPGDNFHPENSHVLPALIRRFDAAARAGEDHVTIWGTGTPRREFLHVDDMAAASLFVLDLDPATYRRETSPMLSHINVGCGQDISILELAQMVAGVVGFDGEIRTNPEQPDGTPRKLMDVSRLARLGWQAEIALRDGIAQTYEWYLQQDPERLRSK
>NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MITPILLCGGSGTRLWPLSRKSYPKQFVPLVGETTLFQASALRLSGEGFAAPMVLTNSDFRFIVTEQLAEAGIDPGAILIEPAGRNTAPAVLAAALWLRARDPDGLMLVAPSDHVVPDAAAFRAAVAAAEPAARAGELVTFGIKPDRAETGYGYLELDGDPGDFSPKVIGLKRFVEKPDLATAEDMLASGQFLWNAGIFLFSVKAIIAAFETHAPDLMVPVQGAVDQGEPDLGFLRLDPAAWDGAADISIDYAVMERAENLAVVPYAGGWSDLGGWDAVWRESGPDGDGIVTQGRATAIECSNSLLRSEDDGLEVVGIGLKDVIAVAMPDAVLVADASRAQEVKKAVAALKAKSARQAEAFPKDHRPWGWFESLVVGERFQVKRIHVHPGAALSLQSHHHRSEHWIVVEGTAKVTVDDSVQLVSENQSVYIPLGAVHRMENPGKVPMVLIEVQTGSYLGEDDIIRYEDIYARK
>NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein
MSDPLSETTPRLALPYLMPAQAQKHVTHNEALRMLDALVQLRLEGFDATTPPTTPTEGAAYGLADSPTDAWAGQGGRLAIWQDAAWQFLTPQPGWRAWVPADQALRVWDGTQWQLPPLSGDRLDRLGIATDADASNRLSLRSPASLLSHDGGGHQLKINKASGSDTASLLFQSNWAGHAEMGLAGNTDFTVKLSPDGSSWDAAMVLKSANGRAGFGTYDPGARLEVSGDDSTLLALTATGSSQDYLTAGDGSGAMFRLSQTGNGYCDGAWTGGGADYAEFFEWEDGNPDGEDRRGVSVVMAGDRIRAAQPGEAPIGVISTTPSILGNDDGGRWQGRSLRDGFGAMLREAGGAPCLNPAYDPTRPYRSRAERAEWDMVGLLGRLRLRTGQPTDPRWIRLRALRPGKNTPPEGLEDWLIR
>NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein
MTQRGSSRMDLQFAGRFGANDQLLDSDLRDLEIHQGANGALQLFAVSGLNGGIASYGLGRGAPVLRDSLYHRALGLAGGEATLAEIGGETRLLVEGSTRSALAFHLIGGNGQLSAQQQASLPGAGAAGLAATVAGDLSGGGSVVYGLANGQLSGWQLSAGGPPGAEVATRGAAAAYARPGAVALELADLGGGAQVLLLADRMEQGIQSYRVDPDNGALSVADSLGAADGLGLAEPTAVESFTAFGSSWAVVAAAGSGSLSLIALGRDGQMSLSDHVLDTAATRFGGATALEVVEVAGEMLVLAAGSDDGLALFRILPEGQLVHVTSLAHASGTEDAGLGLENVTALAAAVVGGDLQIFASSGRAEGLSQFTLSLAELGDVITTDGGRISGTGAADVLAGGIGAVLSGGAGADVFVLRPAEEGRSGSLRITDFEAGQDSLDLSEFDGLRSLEGLQIRSRSDGAVITHQAADGSRTEVVVQSRDGGSLETADLFADGFVFADRMLPPAEAPDPIRYGSGGADRITARSAGDQINGLEGNDTLLGGDGRDSLWGDDGHDRLIGGKGVDRLRGQAGNDVLLGQDARDLLVGGAGRDTLDGGRGGDRLLGGADADLLRGGGENDLLRGGAQGDRLLGQSGRDKLFGQKGNDLLDGGGGHDTLTGGAGADVFVFGAGHGSDRIRDFTQGEDVLHLGRLARAGIAEDMGDLTLQQQGDHTLILTGAGDILLLNQTAAELSADDFIF
>NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase
MPTYQDYRALLVDGADGWHEGSEVIRYHFLTSVPDYYDYDPDFGDYDVGGEYLPEGATVNMDPAERQMMLQAVAAWNEVANLNLIPARGGTADLTFASAHFADAGLFGFIADFPDPSDLGTRPSPAGDLWLNNSNPDQYVPGIGPILGHTSWNTYLHELGHALGLHHPNEMPENPTTPGQFTVMSYLPHPGEADLDQDLQGWALTPMLWDMQALQALYGANTETRTDATSYFGDGDGRGDQAYQYGADDMTVQGGDGVARNVSLTIWDAGGQDLIDASDVAGNSRIDLRPGQYSTIGALENNVAMAAAVRVDGRTLNLIEDAWGGAGNDHLTGNGAANELAGNAGRDTLAGARNSDVLIGGQGSDRLQGGKGHDALEGGRGRDTLKGGAGQDTLDGGDGNDRMAGGRGADVFVFSQGADVVIDFQSNDRIDMRATTGVSDFADLRDDHLEVRGADLVIRDDNGWSLTLQDTAFDVLRADDFLF
>NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase
MQIEDTDLPGVKILTPARFGDARGFFCESWNKARMAEAGLDFDFVQDNHSLSMEVGTLRGLHFQAPPHAQAKLVRCGQGALFDVAVDIRKGSPTYGRWTGVELSAANGRQLLIPAGFLHGFITRSPGTEVLYKCDAYYAPDCDGGVAWDSCGIDWGFDGTPVLSEKDAAAPRFEDLDSPFVWEG
>NC_018422.1|WP_014889412.1|54033_55053_-|hypothetical-protein
MTRRLWLHIGSHKTGSTSLQTALRQGQSDKTLGGWSYLHARPRVDFNPLVRCHGMGAGMHTELRWPFLERRMADADHRGHGDCILSSEMLFWLMDVADLEALRQQLRAHFDEISVVAYLRRQDALALSHRKQVVMGRAAYQFYGAQIRGLPEFQPHMMRYFDYATKLARWEQVFGAGNVTVRRFQRSDLVGGDTVLDFYHLVGLTPPPELPQENAAWSRSQLLAGLWLRQRGYPRQSFAEAVQELPDDGRLMPARAEAAAFLARFEAINRALAARYDPQGPEMFFDCDLSRYPEQGNGEGLAGDAVVTPEVLAELESRARAEMAARELPLDALNPDDRL
>NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein
MSQDRDYIDQEITQIRFIYETLYPETPVETHMWWEKAKLPTPAVQPQDMSYGAEMMALTYIGNLRTGPQETPALPGKRVFVTIPSPRQVAVRESAGGVPWHKRPRKYRAIHALSPILAEQMKYQIEARRWRKLPARHKFSRLACSRGIFETQKMAPEGRHGGKDPAILIGLHWLDVGGAESLGIDSIQWALDAGLRVFVMVGQEGPERLLAKLPEDPRLQLIRTDRYLPRSQTSAFVSQLIAQENIILTHNHHCVPLYDALPTIKLRHPHVVNIDSTHIVEYADGGYPRISGVWSNFIDHHHVISSDLERFYKERFRVYGSKLVLGRLLDDSRRGAEVAPVRIKAGQKRCRVAFVGRMVHQKRPVVALSIIRRLRAWGKRNGVDFRFDMVGEGPYRGAVEHLLTRYRLADVVHLHPAGTDVPALLGDSDILLVPSSNEGLALVCYEAIEAGCVPICSDVGAQAEICPPETLVAWSPLQAVRDSVAVVQRLLREEGFAETVEAGQRARMQALQADPSAREVLDRLYRDALAAVAAEQPLPKEAATRRKTKSKAPA
>NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase
MNIRSSLAAVIVTYNRLDKLKRVIAALQAQTCLPERVFVIDNASTDETGSWLTQLQKDDPRFQHVRLPENIGGAGGFYEGARVAYEEGYDFIWFSDDDAYPDPNAIELLLTGIKDFEARFTWRPSFACSAVKWTNGDLCEMNTPSTVWDWPRFYSPETPYFLVGSCSFVSVLVPRWAIQKHGFPIKEYFIWYDDAEYTQRIAKSYPGIYCPNSVVVHDVPENKGVNYSLVNQANIWKFRYGARNEASFRRREQGWAGVAVFARGVRRQMRQGNVEKSLRREVYKAIWRGCSFNPQIIRPDPDTGV
>NC_018422.1|WP_014889415.1|57705_59013_-|hypothetical-protein
MEPMSDKTGARPKTLVIHIGDHKTGTTTIQNALAVGSIQLHDAKLLYPAKMNHNYLTGFITSYRKGTPLPKHLEDRDGLTEVAAQIAASDADYAVLSAEAFENIPAPEFHDLVETFFRGCADRIHIVAYVRPHAQRILSSYAEQIKIGWYRGSMQEFFDHNLQNGRFHYAPRFAQWRELFGDEFTLRPMIRKELKNGSVLDDFAEVAFDGRPCTVEEFEPENQAMTVRELALMYFLQGQFQEQDPWLRHTLGWELSRQLDRSRGDSEAKVRKLVMARDLAEAATAAYRCDAEVMDATFFEGRPLMQTALRDMEKQSAPCAPSLDPSQFFSPEHLRNLTVMAKIIEGMLERQGKWPSYFHSHRIKDIERHKNARLGLDENGDPLEPEAEMPAGSETAATPAPQSAVTISDTPAQTPPPARVLADAAAGAAPQKDQP
>NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase
MVGAGLSGAVIGRHLAEAGHKITVLDSRDHIGGNCHTERDAETGVMVHVYGPHIFHTDDAEVWDYVNGFETFLPYKNRVKTTSLDPEGRRGVFSLPVNLHTINQFFGKTLRPEEAHDFITEEQADTSITDPQTFEEQALRFVGRDLYEAFFKGYTIKQWGVAPSALPASILKRLPVRFNYDDNYFFHKYQGMPENGYTAMIEKILDHPGITVKLETVFDQSQAADYDHVFYSGPLDGYFNYQLGRLGYRTLDFERFTHQGDYQGCAVMNYGEEAVPYTRITEHKHFAPWESHDGSVCYREFSRAAEPEDIPYYPIRQVEEKALLGEYVALAEQAEGVTFVGRLGTYRYLDMDVTIREALDTARGFLAAQENRAPVPAFFVAPL
>NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein
MIRFENLTKSFWLKGERRIVIDNLNLTLPTGRSLALLGRNGAGKSTLLQLVAGTMRPDHGEIISDGSISWPVGLAASFHGDLSGAENVRFIARIYGVDTDDLVGFVEDFAELGKFYHMPMRSYSSGMRARLTFGASMGIKFDTYLVDEVTAVGDAAFKRKSRDIFTDRMRHSSAILVNHSMRQLRQFCNAGLVLDNGRLRYFSDLDEAIAEHHRLMAV
>NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter
MTQTPPSSLTGRPASEEATSEEAAAADTAASTATGTPAASPAATASDSAPDAAEAAAPAQRVPDPVKQLKRVRRKARKAEAAVAELEARIAEAEQRPAYPLARPASMKKRHWGLVISFVALVLAPLLAVMIYLWTFAEDQYASTAGFTVRSQESSGANDLLGGLAQFAGTSSASDSDILYEFIQSQEMVAAVDAAVDLQGHYSALWPRDWVFALWPEASLEDLTWYWQRIVGISFDSGSGLIEVQALAFDAATAQAITKAIVAESQTRINALNEQARADAMRYARADLDEALERLKDARQSLTSFRTRTRIVDPEADIQGRMGVMNNLQQQLAEALIQYDLLRGTVTAADPRLTKAQQHIDVIRDRINIERQTFTSNNTDTGGVGEDYPSLIAEFERLTVDREYAEESYRAALTALEVARDDAARQSRYLATYINPTRATEPEYPRRAVLAALAGLFLLLTWSILALIYYSIRDRS
>NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease
MASLSSSAPPAQPRPLSPPKTQVTAQAPAQTPAQIPASPAANPHHRHRRSMATLRTVAALVLREMSTRYGRTPGGYLWGILEPLAAILFLSLGFSLVIRTPSLGTSFLLFYATGFLPFNLYQTLSGTVARALAYSRPLLRYPAVTWLDAILARFVLNSLTGIVITTLLITGILAVIDSRTAIDLPPLVEAITLAMVLGLGVGCINAVLMGLFPLWDVAWSIITRPLFLASGVIYIYEDLPPVAQDVLWYNPLLHITGLMRTGFYPTYNADYVSHAYVLLIGMTLTALGLILMRRYHRVILNR
>NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase
MNETLIPEPALQADMQQAGAGRLVAVVVTYNRLAKLKVTLARLLGSPAQELASLVVVDNASNDGTGDWLAGWAAEHPRVDVVTSTTNQGGAGGFALGMQRAMEAHTPDWLVVMDDDGRPEPGGLAAFHAMGQSGALAHWDAVAAAVYFPSGEICEMNRPSRNPFWSLSHFLSTARKGRDGFHIPRRAYDGGLSAIDVTSFVGFFISAAAVRRVGYPDPKLFIYGDDALYTLGLSAAGGRICFAADVRFEHDFSTFSNGDSGQRFRPLWKVYYHHRNLLLLYRQAAGWLFWPVLLLILPKWILKVRHHPGVRRAYLRLTWLAVRDGLLRRLGRSHGEVLAEARE
>NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein
MKTALITGSAGFIGYHLADRLLAAGWRVIGLDCLSPYYDVRLKECRHARLAEHPGFMPIIGKLEDPDRLMGLFATHKPDAVIHLAAQAGVRHSIDAPRDYLEANLIGTFELLEAARAHPPAHMLIASTSSAYGANTQMPFDERQQADHQMSFYAATKKAGETMAHSYAHLYGLPTTMFRFFTVYGPWGRPDMALFKFTKAMQAGQPIDVYNHGRMSRDFTYIDDLVAGITGLIDAVPGDQPVSEQDNLSPVAPFRVVNIGASRPTPLMDYIAALETALGITAQKNLMEMQAGDVPATWADTSLLSQLTGYEPQVPVEEGVARFVTWYRAYYGDAQG

Crispr_ID: NC_018422_3

• CRISPR_ID: NC_018422_3
• CRISPR_location: 53386-53540
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_018422_3

Consensus_repeat	Method
GGTGGTGAAGGCAACGACATCCT	CRISPRCasFinder

spacers of NC_018422_3

>3.1|53409|55|NC_018422|CRISPRCasFinder
GCACGGTAACGATGGTTCGAACGGCGGTGACGCAACCGATGCCGACACTCTGAAA
>3.2|53487|31|NC_018422|CRISPRCasFinder
GTTGGGTGACGGCGGCAATGATGAACTGCGC

CRISPR arrays and Neighbor proteins around NC_018422_3

CRISPR arrays

The CRISPR arrays of NC_018422_3

>merge|NC_018422|3|53386-53540|CRISPRCasFinder
GGCGGTAAAGGCGACGACCTGCTGCACGGTAACGATGGTTCGAACGGCGGTGACGCAACCGATGCCGACACTCTGAAAGGTGGCGACGGTGACGACACCCTGTTGGGTGACGGCGGCAATGATGAACTGCGCGGCGGTGCGGGCGACGACTCCCT

>NC_018422|3|3|53386-53540|CRISPRCasFinder
GGCGGTAAAGGCGACGACCTGCT	GCACGGTAACGATGGTTCGAACGGCGGTGACGCAACCGATGCCGACACTCTGAAA
GGTGGCGACGGTGACGACACCCT	GTTGGGTGACGGCGGCAATGATGAACTGCGC
GGCGGTGCGGGCGACGACTCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224596
NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902
NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl|CDD|226969
NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase	unknown	unknown	gnl|CDD|187550
NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase	unknown	unknown	gnl|CDD|223636
NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein	unknown	unknown	gnl|CDD|371324
NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter	unknown	unknown	gnl|CDD|226055
NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase	unknown	unknown	gnl|CDD|133028
NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|273648
NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213187
NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|224014
NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187563
NC_018422.1|WP_014889415.1|57705_59013_-|hypothetical-protein	unknown	unknown	unknown
NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase	unknown	unknown	gnl|CDD|133028
NC_018422.1|WP_014889412.1|54033_55053_-|hypothetical-protein	unknown	unknown	unknown
NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein	unknown	unknown	gnl|CDD|367564
NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein	unknown	unknown	gnl|CDD|380205
NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831
NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase	unknown	unknown	gnl|CDD|369942
NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl|CDD|376414

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease	gnl|CDD|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	6.0012e-33
NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	1.21351e-92
NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase	gnl|CDD|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase	gnl|CDD|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.91224e-171
NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase	gnl|CDD|223636	COG0562, Glf, UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane].	0
NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein	gnl|CDD|371324	pfam10983, DUF2793, Protein of unknown function (DUF2793). This is a bacterial family of proteins with unknown function.	1.12348e-37
NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase	gnl|CDD|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.97558e-95
NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl|CDD|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213187	cd03220, ABC_KpsT_Wzt, ATP-binding cassette component of polysaccharide transport system. The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.	7.74672e-87
NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase	gnl|CDD|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187563	cd05253, UDP_GE_SDE_e, UDP glucuronic acid epimerase, extended (e) SDRs. This subgroup contains UDP-D-glucuronic acid 4-epimerase, an extended SDR, which catalyzes the conversion of UDP-alpha-D-glucuronic acid to UDP-alpha-D-galacturonic acid. This group has the SDR's canonical catalytic tetrad and the TGxxGxxG NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.4863e-174
NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter	gnl|CDD|226055	COG3524, KpsE, Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane].	1.14417e-63
NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase	gnl|CDD|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.15755e-58
NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein	gnl|CDD|367564	pfam03567, Sulfotransfer_2, Sulfotransferase family. This family includes a variety of sulfotransferase enzymes. Chondroitin 6-sulfotransferase catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine residue of chondroitin. This family also includes Heparan sulfate 2-O-sulfotransferase (HS2ST) and Heparan sulfate 6-sulfotransferase (HS6ST). Heparan sulfate (HS) is a co-receptor for a number of growth factors, morphogens, and adhesion proteins. HS biosynthetic modifications may determine the strength and outcome of HS-ligand interactions. Mice that lack HS2ST undergo developmental failure only after midgestation,the most dramatic effect being the complete failure of kidney development. Heparan sulphate 6- O -sulfotransferase (HS6ST) catalyzes the transfer of sulphate from adenosine 3'-phosphate, 5'-phosphosulphate to the 6th position of the N -sulphoglucosamine residue in heparan sulphate.	0.00667548
NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.92398e-22
NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	6.9571e-23
NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase	gnl|CDD|369942	pfam08548, Peptidase_M10_C, Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.	8.15701e-21
NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl|CDD|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	7.87907e-101

Protein sequences

>NC_018422.1|WP_014889410.1|50497_51274_+|sulfotransferase-family-2-domain-containing-protein
MSQVSSQTSGSRTVAETAFEARFSPRLVAAETYHDSNDVILFMHIPKTAGMSVGKALQAAFDIFHPVSWENTNQSFRNKTRKALYRRSDEATPCRQVLMGHFAWSDVMYWRHQELPLKCATIIRDPLDRFVSNYRYNTSDKHPQHEAFAARYPTLESYAHVLPLDYQLSLMTGAFYSFDHALEKLNRYYSFIGVTEHLGASLQHFRRSHGLAELTEHRENTGSKAKAAEDIPDAVRNIVGEKSRNDARLHQLVSRCYG
>NC_018422.1|WP_014889408.1|48141_49998_-|type-I-secretion-system-permease/ATPase
MARTSAQHSGSAHKPGLGEIRKARKGNRGAFWLIGVFSFFANLLMLTSPLYMMQVYDRVLGSRSLETLVALTVLAGFLFLIMGVLDYVRGRILARVGARFHDQLETRVFNAVQDKSAAGFNDDIAKVGLRDLEAMQKALSSPIVSAFFDLPWTPLFLGLIAVFHPLLGLLALIGGAVLVVFALANQMISKAAVENASMMAASAHQVSDGMRNNAELIQGLGMRRAAFAKWRMLRSQAVGSELSAADMTGGFSTATRTFRLALQSAMLGTGAYLVLTEGLTPGVMIASSIIMGRALAPIETLIGQWALVQRAMQAQERLAQMLTETPERPAPMKLARPAAKLEVQGVALVPPVAPGQVAKPALQGLNFSIQPGQALGVIGASGAGKSSLARALIGVWHPVSGKIRLDGAALNQYDMDDLGSYIGYLPQQVTLFDGTIAENIARLSMMPDPDQVVAAARKAAVHDMILQLPQGYDTPVRVASNRLSGGQVQRIGLARALYGDPVLLVLDEPNSNLDNEGSQALNLAVSHAKKDGRAVIIMAHRPAAIQLCDLILILDNGTQRAFGPRDAVLGEHLQNPQVVQKKQAQQQAAAPSTSAPSTPTQKQPAPKQAAPKQAEAKS
>NC_018422.1|WP_014889407.1|46837_48145_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MSDTSKSYPIRGLTIAGLLAMGLLVGGLGQWAATAEISGAVIASGSIKVEQNRQVVQHPYGGVVDEVLVSEGDLVEEDALLLRLEPSELLAERQIVEGQLAETLARRSRYSAERDEAEEVTFAELLFELSGTHVQTEELINGQKRLFEARLVNLRARISRLQERIGQIQSQIDGIEAQQSALQEQLVLIGQELENQQSLLSQGLAQSSRVLSLQREQSRLRGQAGALTAQKAQAEGQVTELGLEILNQRSARREEAITTLRDLQVRELELIERRNLILQRLSRLEVRAPVSGLVYDLNVFARKSVIRAADPLMYLIPQSQPLVISAQVAPSDIDQVYLNQPVSLNFSSFNQRTTPTLFGTVSTVSADSFVDPQTGRSYYVVEARLNKGEIDRLPEGNVLVPGMPVETFIQTNSRTPFAYLLQPFTDYLNRAFRES
>NC_018422.1|WP_014889406.1|45530_46649_-|GDP-mannose-4,6-dehydratase
MKKALITGVTGQDGSYLAEFLLEKGYEVHGLKRRASSFNTQRVDHIYQDPHTDHARFKLHYGDLTDTSNLTRLLSEIEPDEVYNLGAQSHVAVSFEAPEYTADVDGIGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQETPQRETTPFYPRSPYAVAKLYSYWITVNYREAYGIYACNGILFNHESPRRGETFVTRKITRGLANIAQGLEECLYMGNIDALRDWGHARDYVRMQWMMLQQEVPEDFVIATGKQYSVRQFITWSAQELGLTLAFSGEGVEEIATVTAIEGDMAPALKVGDVVLRIDPRYFRPAEVETLLGDPTKAKQKLGWVPEITTEEMCAEMVREDLKTARRHALLKEHGMDLPVSTEG
>NC_018422.1|WP_014889405.1|44536_45526_-|GDP-L-fucose-synthase
MGTSTVKIYVAGHRGMVGGAILRRLQARRAAGEDIQLITRTSAELDLTDQAMVQAFFAAERPDQVVLAAAKVGGIHANNAYPAQFIYENLMMECNVIHAAHQQGVERLLQLGSSCIYPKHAPQPMAEAALLSDVLEATNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPGDNFHPENSHVLPALIRRFDAAARAGEDHVTIWGTGTPRREFLHVDDMAAASLFVLDLDPATYRRETSPMLSHINVGCGQDISILELAQMVAGVVGFDGEIRTNPEQPDGTPRKLMDVSRLARLGWQAEIALRDGIAQTYEWYLQQDPERLRSK
>NC_018422.1|WP_014889404.1|42987_44409_-|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MITPILLCGGSGTRLWPLSRKSYPKQFVPLVGETTLFQASALRLSGEGFAAPMVLTNSDFRFIVTEQLAEAGIDPGAILIEPAGRNTAPAVLAAALWLRARDPDGLMLVAPSDHVVPDAAAFRAAVAAAEPAARAGELVTFGIKPDRAETGYGYLELDGDPGDFSPKVIGLKRFVEKPDLATAEDMLASGQFLWNAGIFLFSVKAIIAAFETHAPDLMVPVQGAVDQGEPDLGFLRLDPAAWDGAADISIDYAVMERAENLAVVPYAGGWSDLGGWDAVWRESGPDGDGIVTQGRATAIECSNSLLRSEDDGLEVVGIGLKDVIAVAMPDAVLVADASRAQEVKKAVAALKAKSARQAEAFPKDHRPWGWFESLVVGERFQVKRIHVHPGAALSLQSHHHRSEHWIVVEGTAKVTVDDSVQLVSENQSVYIPLGAVHRMENPGKVPMVLIEVQTGSYLGEDDIIRYEDIYARK
>NC_018422.1|WP_014889403.1|41708_42965_+|DUF2793-domain-containing-protein
MSDPLSETTPRLALPYLMPAQAQKHVTHNEALRMLDALVQLRLEGFDATTPPTTPTEGAAYGLADSPTDAWAGQGGRLAIWQDAAWQFLTPQPGWRAWVPADQALRVWDGTQWQLPPLSGDRLDRLGIATDADASNRLSLRSPASLLSHDGGGHQLKINKASGSDTASLLFQSNWAGHAEMGLAGNTDFTVKLSPDGSSWDAAMVLKSANGRAGFGTYDPGARLEVSGDDSTLLALTATGSSQDYLTAGDGSGAMFRLSQTGNGYCDGAWTGGGADYAEFFEWEDGNPDGEDRRGVSVVMAGDRIRAAQPGEAPIGVISTTPSILGNDDGGRWQGRSLRDGFGAMLREAGGAPCLNPAYDPTRPYRSRAERAEWDMVGLLGRLRLRTGQPTDPRWIRLRALRPGKNTPPEGLEDWLIR
>NC_018422.1|WP_014889402.1|39221_41441_-|hypothetical-protein
MTQRGSSRMDLQFAGRFGANDQLLDSDLRDLEIHQGANGALQLFAVSGLNGGIASYGLGRGAPVLRDSLYHRALGLAGGEATLAEIGGETRLLVEGSTRSALAFHLIGGNGQLSAQQQASLPGAGAAGLAATVAGDLSGGGSVVYGLANGQLSGWQLSAGGPPGAEVATRGAAAAYARPGAVALELADLGGGAQVLLLADRMEQGIQSYRVDPDNGALSVADSLGAADGLGLAEPTAVESFTAFGSSWAVVAAAGSGSLSLIALGRDGQMSLSDHVLDTAATRFGGATALEVVEVAGEMLVLAAGSDDGLALFRILPEGQLVHVTSLAHASGTEDAGLGLENVTALAAAVVGGDLQIFASSGRAEGLSQFTLSLAELGDVITTDGGRISGTGAADVLAGGIGAVLSGGAGADVFVLRPAEEGRSGSLRITDFEAGQDSLDLSEFDGLRSLEGLQIRSRSDGAVITHQAADGSRTEVVVQSRDGGSLETADLFADGFVFADRMLPPAEAPDPIRYGSGGADRITARSAGDQINGLEGNDTLLGGDGRDSLWGDDGHDRLIGGKGVDRLRGQAGNDVLLGQDARDLLVGGAGRDTLDGGRGGDRLLGGADADLLRGGGENDLLRGGAQGDRLLGQSGRDKLFGQKGNDLLDGGGGHDTLTGGAGADVFVFGAGHGSDRIRDFTQGEDVLHLGRLARAGIAEDMGDLTLQQQGDHTLILTGAGDILLLNQTAAELSADDFIF
>NC_018422.1|WP_014889401.1|37701_39153_+|metallopeptidase
MPTYQDYRALLVDGADGWHEGSEVIRYHFLTSVPDYYDYDPDFGDYDVGGEYLPEGATVNMDPAERQMMLQAVAAWNEVANLNLIPARGGTADLTFASAHFADAGLFGFIADFPDPSDLGTRPSPAGDLWLNNSNPDQYVPGIGPILGHTSWNTYLHELGHALGLHHPNEMPENPTTPGQFTVMSYLPHPGEADLDQDLQGWALTPMLWDMQALQALYGANTETRTDATSYFGDGDGRGDQAYQYGADDMTVQGGDGVARNVSLTIWDAGGQDLIDASDVAGNSRIDLRPGQYSTIGALENNVAMAAAVRVDGRTLNLIEDAWGGAGNDHLTGNGAANELAGNAGRDTLAGARNSDVLIGGQGSDRLQGGKGHDALEGGRGRDTLKGGAGQDTLDGGDGNDRMAGGRGADVFVFSQGADVVIDFQSNDRIDMRATTGVSDFADLRDDHLEVRGADLVIRDDNGWSLTLQDTAFDVLRADDFLF
>NC_018422.1|WP_044041144.1|36936_37491_-|dTDP-4-dehydrorhamnose-3,5-epimerase
MQIEDTDLPGVKILTPARFGDARGFFCESWNKARMAEAGLDFDFVQDNHSLSMEVGTLRGLHFQAPPHAQAKLVRCGQGALFDVAVDIRKGSPTYGRWTGVELSAANGRQLLIPAGFLHGFITRSPGTEVLYKCDAYYAPDCDGGVAWDSCGIDWGFDGTPVLSEKDAAAPRFEDLDSPFVWEG
>NC_018422.1|WP_014889412.1|54033_55053_-|hypothetical-protein
MTRRLWLHIGSHKTGSTSLQTALRQGQSDKTLGGWSYLHARPRVDFNPLVRCHGMGAGMHTELRWPFLERRMADADHRGHGDCILSSEMLFWLMDVADLEALRQQLRAHFDEISVVAYLRRQDALALSHRKQVVMGRAAYQFYGAQIRGLPEFQPHMMRYFDYATKLARWEQVFGAGNVTVRRFQRSDLVGGDTVLDFYHLVGLTPPPELPQENAAWSRSQLLAGLWLRQRGYPRQSFAEAVQELPDDGRLMPARAEAAAFLARFEAINRALAARYDPQGPEMFFDCDLSRYPEQGNGEGLAGDAVVTPEVLAELESRARAEMAARELPLDALNPDDRL
>NC_018422.1|WP_014889413.1|55049_56714_-|glycosyltransferase-family-4-protein
MSQDRDYIDQEITQIRFIYETLYPETPVETHMWWEKAKLPTPAVQPQDMSYGAEMMALTYIGNLRTGPQETPALPGKRVFVTIPSPRQVAVRESAGGVPWHKRPRKYRAIHALSPILAEQMKYQIEARRWRKLPARHKFSRLACSRGIFETQKMAPEGRHGGKDPAILIGLHWLDVGGAESLGIDSIQWALDAGLRVFVMVGQEGPERLLAKLPEDPRLQLIRTDRYLPRSQTSAFVSQLIAQENIILTHNHHCVPLYDALPTIKLRHPHVVNIDSTHIVEYADGGYPRISGVWSNFIDHHHVISSDLERFYKERFRVYGSKLVLGRLLDDSRRGAEVAPVRIKAGQKRCRVAFVGRMVHQKRPVVALSIIRRLRAWGKRNGVDFRFDMVGEGPYRGAVEHLLTRYRLADVVHLHPAGTDVPALLGDSDILLVPSSNEGLALVCYEAIEAGCVPICSDVGAQAEICPPETLVAWSPLQAVRDSVAVVQRLLREEGFAETVEAGQRARMQALQADPSAREVLDRLYRDALAAVAAEQPLPKEAATRRKTKSKAPA
>NC_018422.1|WP_014889414.1|56791_57709_-|glycosyltransferase
MNIRSSLAAVIVTYNRLDKLKRVIAALQAQTCLPERVFVIDNASTDETGSWLTQLQKDDPRFQHVRLPENIGGAGGFYEGARVAYEEGYDFIWFSDDDAYPDPNAIELLLTGIKDFEARFTWRPSFACSAVKWTNGDLCEMNTPSTVWDWPRFYSPETPYFLVGSCSFVSVLVPRWAIQKHGFPIKEYFIWYDDAEYTQRIAKSYPGIYCPNSVVVHDVPENKGVNYSLVNQANIWKFRYGARNEASFRRREQGWAGVAVFARGVRRQMRQGNVEKSLRREVYKAIWRGCSFNPQIIRPDPDTGV
>NC_018422.1|WP_014889415.1|57705_59013_-|hypothetical-protein
MEPMSDKTGARPKTLVIHIGDHKTGTTTIQNALAVGSIQLHDAKLLYPAKMNHNYLTGFITSYRKGTPLPKHLEDRDGLTEVAAQIAASDADYAVLSAEAFENIPAPEFHDLVETFFRGCADRIHIVAYVRPHAQRILSSYAEQIKIGWYRGSMQEFFDHNLQNGRFHYAPRFAQWRELFGDEFTLRPMIRKELKNGSVLDDFAEVAFDGRPCTVEEFEPENQAMTVRELALMYFLQGQFQEQDPWLRHTLGWELSRQLDRSRGDSEAKVRKLVMARDLAEAATAAYRCDAEVMDATFFEGRPLMQTALRDMEKQSAPCAPSLDPSQFFSPEHLRNLTVMAKIIEGMLERQGKWPSYFHSHRIKDIERHKNARLGLDENGDPLEPEAEMPAGSETAATPAPQSAVTISDTPAQTPPPARVLADAAAGAAPQKDQP
>NC_018422.1|WP_014889416.1|59112_60264_-|UDP-galactopyranose-mutase
MVGAGLSGAVIGRHLAEAGHKITVLDSRDHIGGNCHTERDAETGVMVHVYGPHIFHTDDAEVWDYVNGFETFLPYKNRVKTTSLDPEGRRGVFSLPVNLHTINQFFGKTLRPEEAHDFITEEQADTSITDPQTFEEQALRFVGRDLYEAFFKGYTIKQWGVAPSALPASILKRLPVRFNYDDNYFFHKYQGMPENGYTAMIEKILDHPGITVKLETVFDQSQAADYDHVFYSGPLDGYFNYQLGRLGYRTLDFERFTHQGDYQGCAVMNYGEEAVPYTRITEHKHFAPWESHDGSVCYREFSRAAEPEDIPYYPIRQVEEKALLGEYVALAEQAEGVTFVGRLGTYRYLDMDVTIREALDTARGFLAAQENRAPVPAFFVAPL
>NC_018422.1|WP_014876631.1|60424_61081_-|ABC-transporter-ATP-binding-protein
MIRFENLTKSFWLKGERRIVIDNLNLTLPTGRSLALLGRNGAGKSTLLQLVAGTMRPDHGEIISDGSISWPVGLAASFHGDLSGAENVRFIARIYGVDTDDLVGFVEDFAELGKFYHMPMRSYSSGMRARLTFGASMGIKFDTYLVDEVTAVGDAAFKRKSRDIFTDRMRHSSAILVNHSMRQLRQFCNAGLVLDNGRLRYFSDLDEAIAEHHRLMAV
>NC_018422.1|WP_014889417.1|61098_62529_-|sugar-transporter
MTQTPPSSLTGRPASEEATSEEAAAADTAASTATGTPAASPAATASDSAPDAAEAAAPAQRVPDPVKQLKRVRRKARKAEAAVAELEARIAEAEQRPAYPLARPASMKKRHWGLVISFVALVLAPLLAVMIYLWTFAEDQYASTAGFTVRSQESSGANDLLGGLAQFAGTSSASDSDILYEFIQSQEMVAAVDAAVDLQGHYSALWPRDWVFALWPEASLEDLTWYWQRIVGISFDSGSGLIEVQALAFDAATAQAITKAIVAESQTRINALNEQARADAMRYARADLDEALERLKDARQSLTSFRTRTRIVDPEADIQGRMGVMNNLQQQLAEALIQYDLLRGTVTAADPRLTKAQQHIDVIRDRINIERQTFTSNNTDTGGVGEDYPSLIAEFERLTVDREYAEESYRAALTALEVARDDAARQSRYLATYINPTRATEPEYPRRAVLAALAGLFLLLTWSILALIYYSIRDRS
>NC_018422.1|WP_014876633.1|62645_63554_+|ABC-transporter-permease
MASLSSSAPPAQPRPLSPPKTQVTAQAPAQTPAQIPASPAANPHHRHRRSMATLRTVAALVLREMSTRYGRTPGGYLWGILEPLAAILFLSLGFSLVIRTPSLGTSFLLFYATGFLPFNLYQTLSGTVARALAYSRPLLRYPAVTWLDAILARFVLNSLTGIVITTLLITGILAVIDSRTAIDLPPLVEAITLAMVLGLGVGCINAVLMGLFPLWDVAWSIITRPLFLASGVIYIYEDLPPVAQDVLWYNPLLHITGLMRTGFYPTYNADYVSHAYVLLIGMTLTALGLILMRRYHRVILNR
>NC_018422.1|WP_014889418.1|63562_64594_-|glycosyltransferase
MNETLIPEPALQADMQQAGAGRLVAVVVTYNRLAKLKVTLARLLGSPAQELASLVVVDNASNDGTGDWLAGWAAEHPRVDVVTSTTNQGGAGGFALGMQRAMEAHTPDWLVVMDDDGRPEPGGLAAFHAMGQSGALAHWDAVAAAVYFPSGEICEMNRPSRNPFWSLSHFLSTARKGRDGFHIPRRAYDGGLSAIDVTSFVGFFISAAAVRRVGYPDPKLFIYGDDALYTLGLSAAGGRICFAADVRFEHDFSTFSNGDSGQRFRPLWKVYYHHRNLLLLYRQAAGWLFWPVLLLILPKWILKVRHHPGVRRAYLRLTWLAVRDGLLRRLGRSHGEVLAEARE
>NC_018422.1|WP_014889419.1|64748_65759_+|NAD-dependent-epimerase/dehydratase-family-protein
MKTALITGSAGFIGYHLADRLLAAGWRVIGLDCLSPYYDVRLKECRHARLAEHPGFMPIIGKLEDPDRLMGLFATHKPDAVIHLAAQAGVRHSIDAPRDYLEANLIGTFELLEAARAHPPAHMLIASTSSAYGANTQMPFDERQQADHQMSFYAATKKAGETMAHSYAHLYGLPTTMFRFFTVYGPWGRPDMALFKFTKAMQAGQPIDVYNHGRMSRDFTYIDDLVAGITGLIDAVPGDQPVSEQDNLSPVAPFRVVNIGASRPTPLMDYIAALETALGITAQKNLMEMQAGDVPATWADTSLLSQLTGYEPQVPVEEGVARFVTWYRAYYGDAQG

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	NZ_CP031955	Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence	53291-53321	0	1.0
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	NC_018422	Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence	53055-53085	0	1.0
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP031955	Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence	53459-53489	0	1.0
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NC_018422	Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence	53223-53253	0	1.0
NC_018422_3	3.1|53409|55|NC_018422|CRISPRCasFinder	53409-53463	55	NZ_CP031955	Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence	53645-53699	0	1.0
NC_018422_3	3.1|53409|55|NC_018422|CRISPRCasFinder	53409-53463	55	NC_018422	Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence	53409-53463	0	1.0
NC_018422_3	3.2|53487|31|NC_018422|CRISPRCasFinder	53487-53517	31	NZ_CP031955	Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence	53723-53753	0	1.0
NC_018422_3	3.2|53487|31|NC_018422|CRISPRCasFinder	53487-53517	31	NC_018422	Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence	53487-53517	0	1.0
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	NC_023142	Phaeobacter gallaeciensis DSM 26640 plasmid pGal_F69, complete sequence	18565-18595	1	0.968
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	NZ_CP010593	Phaeobacter gallaeciensis strain P11 plasmid pP11_e, complete sequence	18562-18592	1	0.968
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP010605	Phaeobacter inhibens strain P83 plasmid pP83_f, complete sequence	18406-18436	1	0.968
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP010711	Phaeobacter inhibens strain P66 plasmid pP66_f, complete sequence	18406-18436	1	0.968
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	NZ_CP010732	Phaeobacter inhibens strain P88 plasmid pP88_g, complete sequence	18541-18571	2	0.935
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP010655	Phaeobacter inhibens strain P54 plasmid pP54_e, complete sequence	18295-18325	2	0.935
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP010648	Phaeobacter piscinae strain P36 plasmid pP36_e, complete sequence	18403-18433	2	0.935
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NC_023142	Phaeobacter gallaeciensis DSM 26640 plasmid pGal_F69, complete sequence	18397-18427	3	0.903
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP010732	Phaeobacter inhibens strain P88 plasmid pP88_g, complete sequence	18373-18403	3	0.903
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP010593	Phaeobacter gallaeciensis strain P11 plasmid pP11_e, complete sequence	18394-18424	3	0.903
NC_018422_3	3.2|53487|31|NC_018422|CRISPRCasFinder	53487-53517	31	NC_023142	Phaeobacter gallaeciensis DSM 26640 plasmid pGal_F69, complete sequence	18142-18172	3	0.903
NC_018422_3	3.2|53487|31|NC_018422|CRISPRCasFinder	53487-53517	31	NZ_CP010593	Phaeobacter gallaeciensis strain P11 plasmid pP11_e, complete sequence	18139-18169	3	0.903
NC_018422_3	3.2|53487|31|NC_018422|CRISPRCasFinder	53487-53517	31	NZ_CP010605	Phaeobacter inhibens strain P83 plasmid pP83_f, complete sequence	18142-18172	4	0.871
NC_018422_3	3.2|53487|31|NC_018422|CRISPRCasFinder	53487-53517	31	NZ_CP010711	Phaeobacter inhibens strain P66 plasmid pP66_f, complete sequence	18142-18172	4	0.871
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP032344	Azospirillum brasilense strain MTCC4038 plasmid p5, complete sequence	146736-146766	5	0.839
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP033323	Azospirillum brasilense strain Cd plasmid p5, complete sequence	261248-261278	5	0.839
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP033317	Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence	70310-70340	5	0.839
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP012919	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence	36705-36735	5	0.839
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	773376-773406	5	0.839
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	443154-443184	5	0.839
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	360092-360122	6	0.806
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	NC_011987	Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence	224765-224795	7	0.774
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP009358	Vibrio tubiashii ATCC 19109 plasmid p57, complete sequence	13507-13537	7	0.774
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	74504-74534	7	0.774
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	832090-832120	7	0.774
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	49638-49668	8	0.742
NC_018422_1	1.1|53055|31|NC_018422|CRISPRCasFinder	53055-53085	31	MT188704	Mesorhizobium phage Cp1R7A-A1, complete genome	117703-117733	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP031955	Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence	53513-53543	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NC_018422	Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence	53277-53307	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NC_009926	Acaryochloris marina MBIC11017 plasmid pREB1, complete sequence	289592-289622	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP032347	Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence	360119-360149	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	713446-713476	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP022363	Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence	72515-72545	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP010598	Phaeobacter inhibens strain P10 plasmid pP10_c, complete sequence	18156-18186	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NC_018288	Phaeobacter inhibens DSM 17395 plasmid pPGA1_65, complete sequence	48186-48216	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP014527	Haematospirillum jordaniae strain H5569 plasmid unnamed 2, complete sequence	162710-162740	8	0.742
NC_018422_3	3.2|53487|31|NC_018422|CRISPRCasFinder	53487-53517	31	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	461474-461504	8	0.742
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP048425	Rhizobium daejeonense strain KACC 13094 plasmid unnamed2, complete sequence	295900-295930	9	0.71
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	74342-74372	9	0.71
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP019311	Phaeobacter inhibens strain DOK1-1 plasmid pDOK1-1-4, complete sequence	54105-54135	9	0.71
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP013536	Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence	788763-788793	9	0.71
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	118305-118335	9	0.71
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP013546	Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence	125208-125238	9	0.71
NC_018422_2	2.1|53223|31|NC_018422|CRISPRCasFinder	53223-53253	31	NZ_CP021372	Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence	10173-10203	10	0.677

1. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to NZ_CP031955 (Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence) position: , mismatch: 0, identity: 1.0

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
gaatggccttggcgatgttgacaccctggtc	Protospacer
*******************************

2. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to NC_018422 (Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence) position: , mismatch: 0, identity: 1.0

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
gaatggccttggcgatgttgacaccctggtc	Protospacer
*******************************

3. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP031955 (Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence) position: , mismatch: 0, identity: 1.0

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
cgacggtggtgaaggcaacgacatcctgcgt	Protospacer
*******************************

4. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NC_018422 (Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence) position: , mismatch: 0, identity: 1.0

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
cgacggtggtgaaggcaacgacatcctgcgt	Protospacer
*******************************

5. spacer 3.1|53409|55|NC_018422|CRISPRCasFinder matches to NZ_CP031955 (Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence) position: , mismatch: 0, identity: 1.0

gcacggtaacgatggttcgaacggcggtgacgcaaccgatgccgacactctgaaa	CRISPR spacer
gcacggtaacgatggttcgaacggcggtgacgcaaccgatgccgacactctgaaa	Protospacer
*******************************************************

6. spacer 3.1|53409|55|NC_018422|CRISPRCasFinder matches to NC_018422 (Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence) position: , mismatch: 0, identity: 1.0

gcacggtaacgatggttcgaacggcggtgacgcaaccgatgccgacactctgaaa	CRISPR spacer
gcacggtaacgatggttcgaacggcggtgacgcaaccgatgccgacactctgaaa	Protospacer
*******************************************************

7. spacer 3.2|53487|31|NC_018422|CRISPRCasFinder matches to NZ_CP031955 (Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence) position: , mismatch: 0, identity: 1.0

gttgggtgacggcggcaatgatgaactgcgc	CRISPR spacer
gttgggtgacggcggcaatgatgaactgcgc	Protospacer
*******************************

8. spacer 3.2|53487|31|NC_018422|CRISPRCasFinder matches to NC_018422 (Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence) position: , mismatch: 0, identity: 1.0

gttgggtgacggcggcaatgatgaactgcgc	CRISPR spacer
gttgggtgacggcggcaatgatgaactgcgc	Protospacer
*******************************

9. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to NC_023142 (Phaeobacter gallaeciensis DSM 26640 plasmid pGal_F69, complete sequence) position: , mismatch: 1, identity: 0.968

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
gaacggccttggcgatgttgacaccctggtc	Protospacer
***.***************************

10. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to NZ_CP010593 (Phaeobacter gallaeciensis strain P11 plasmid pP11_e, complete sequence) position: , mismatch: 1, identity: 0.968

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
gaacggccttggcgatgttgacaccctggtc	Protospacer
***.***************************

11. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP010605 (Phaeobacter inhibens strain P83 plasmid pP83_f, complete sequence) position: , mismatch: 1, identity: 0.968

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
cgacggtggtgaaggcaacgacatcctgcgc	Protospacer
******************************.

12. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP010711 (Phaeobacter inhibens strain P66 plasmid pP66_f, complete sequence) position: , mismatch: 1, identity: 0.968

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
cgacggtggtgaaggcaacgacatcctgcgc	Protospacer
******************************.

13. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to NZ_CP010732 (Phaeobacter inhibens strain P88 plasmid pP88_g, complete sequence) position: , mismatch: 2, identity: 0.935

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
gaacggccttggcgatgttgacaccctgatc	Protospacer
***.************************.**

14. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP010655 (Phaeobacter inhibens strain P54 plasmid pP54_e, complete sequence) position: , mismatch: 2, identity: 0.935

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
cgatggtggtgaaggcaacgacatcctgcgc	Protospacer
***.**************************.

15. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP010648 (Phaeobacter piscinae strain P36 plasmid pP36_e, complete sequence) position: , mismatch: 2, identity: 0.935

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
cgacggtggtgcaggcaacgacatcctgcgc	Protospacer
*********** ******************.

16. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NC_023142 (Phaeobacter gallaeciensis DSM 26640 plasmid pGal_F69, complete sequence) position: , mismatch: 3, identity: 0.903

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
taccggtggtgaaggcaacgacatcctgcgt	Protospacer
.. ****************************

17. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP010732 (Phaeobacter inhibens strain P88 plasmid pP88_g, complete sequence) position: , mismatch: 3, identity: 0.903

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
taccggtggtgaaggcaacgacatcctgcgt	Protospacer
.. ****************************

18. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP010593 (Phaeobacter gallaeciensis strain P11 plasmid pP11_e, complete sequence) position: , mismatch: 3, identity: 0.903

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
taccggtggtgaaggcaacgacatcctgcgt	Protospacer
.. ****************************

19. spacer 3.2|53487|31|NC_018422|CRISPRCasFinder matches to NC_023142 (Phaeobacter gallaeciensis DSM 26640 plasmid pGal_F69, complete sequence) position: , mismatch: 3, identity: 0.903

gttgggtgacggcggcaatgatgaactgcgc	CRISPR spacer
gaaaggtgacggcggcaatgatgaactgcgc	Protospacer
*  .***************************

20. spacer 3.2|53487|31|NC_018422|CRISPRCasFinder matches to NZ_CP010593 (Phaeobacter gallaeciensis strain P11 plasmid pP11_e, complete sequence) position: , mismatch: 3, identity: 0.903

gttgggtgacggcggcaatgatgaactgcgc	CRISPR spacer
gaaaggtgacggcggcaatgatgaactgcgc	Protospacer
*  .***************************

21. spacer 3.2|53487|31|NC_018422|CRISPRCasFinder matches to NZ_CP010605 (Phaeobacter inhibens strain P83 plasmid pP83_f, complete sequence) position: , mismatch: 4, identity: 0.871

gttgggtgacggcggcaatgatgaactgcgc	CRISPR spacer
caacggtgacggcggcaatgatgaactgcgc	Protospacer
    ***************************

22. spacer 3.2|53487|31|NC_018422|CRISPRCasFinder matches to NZ_CP010711 (Phaeobacter inhibens strain P66 plasmid pP66_f, complete sequence) position: , mismatch: 4, identity: 0.871

gttgggtgacggcggcaatgatgaactgcgc	CRISPR spacer
caacggtgacggcggcaatgatgaactgcgc	Protospacer
    ***************************

23. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP032344 (Azospirillum brasilense strain MTCC4038 plasmid p5, complete sequence) position: , mismatch: 5, identity: 0.839

cgacggtggtgaaggcaacgacatcctgcgt-	CRISPR spacer
gttcggtggtgaaggcaacgacatctt-cgtg	Protospacer
   **********************.* *** 

24. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP033323 (Azospirillum brasilense strain Cd plasmid p5, complete sequence) position: , mismatch: 5, identity: 0.839

cgacggtggtgaaggcaacgacatcctgcgt-	CRISPR spacer
gttcggtggtgaaggcaacgacatctt-cgtg	Protospacer
   **********************.* *** 

25. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP033317 (Azospirillum brasilense strain Sp 7 plasmid p5, complete sequence) position: , mismatch: 5, identity: 0.839

cgacggtggtgaaggcaacgacatcctgcgt-	CRISPR spacer
gttcggtggtgaaggcaacgacatctt-cgtg	Protospacer
   **********************.* *** 

26. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP012919 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p5, complete sequence) position: , mismatch: 5, identity: 0.839

cgacggtggtgaaggcaacgacatcctgcgt-	CRISPR spacer
gttcggtggtgaaggcaacgacatctt-cgtg	Protospacer
   **********************.* *** 

27. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 5, identity: 0.839

cgacggtggtgaaggcaacgacatcctgcgt-	CRISPR spacer
gaacggtggcgacggcaacgacatcct-cgtc	Protospacer
 .*******.** ************** *** 

28. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 5, identity: 0.839

cgacggtggtgaaggcaacgacatcctgcgt-	CRISPR spacer
gaacggtggcgacggcaacgacatcct-cgtc	Protospacer
 .*******.** ************** *** 

29. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.806

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
ggacggtggtgcgggcaacgacatcctggtg	Protospacer
 ********** .***************   

30. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to NC_011987 (Agrobacterium radiobacter K84 plasmid pAtK84c, complete sequence) position: , mismatch: 7, identity: 0.774

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
gctcgcgcttggcgctgttgacagcctggtc	Protospacer
*  .*  ******* ******** *******

31. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP009358 (Vibrio tubiashii ATCC 19109 plasmid p57, complete sequence) position: , mismatch: 7, identity: 0.774

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
catcggtggtgaaggcaacgccatcgatctt	Protospacer
*. ***************** ****   * *

32. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 7, identity: 0.774

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gcaggggggtgcaggcaacgacatcctgttt	Protospacer
  * ** **** ****************. *

33. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 7, identity: 0.774

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
caacggaggtgacggcaacgacatcatctat	Protospacer
*.**** ***** ************ * ..*

34. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 8, identity: 0.742

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
aggtgaagttggcgatgttgacgcccaggtc	Protospacer
...**.  **************.*** ****

35. spacer 1.1|53055|31|NC_018422|CRISPRCasFinder matches to MT188704 (Mesorhizobium phage Cp1R7A-A1, complete genome) position: , mismatch: 8, identity: 0.742

gaatggccttggcgatgttgacaccctggtc	CRISPR spacer
tgatggccttggcgaggttgtcacctgcggc	Protospacer
 .************* **** ****.  * *

36. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP031955 (Phaeobacter inhibens strain 2.10 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gaatggtggtgaaggcaacgacaccctcttc	Protospacer
 .*.*******************.*** . .

37. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NC_018422 (Phaeobacter inhibens 2.10 plasmid pPGA2_71, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gaatggtggtgaaggcaacgacaccctcttc	Protospacer
 .*.*******************.*** . .

38. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NC_009926 (Acaryochloris marina MBIC11017 plasmid pREB1, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gctaggtggtgaaggcaacgacatcctctta	Protospacer
    *********************** .  

39. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP032347 (Azospirillum brasilense strain MTCC4039 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gtccggcggtgacggcaacgacatcctggac	Protospacer
   ***.***** *************** ..

40. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gtccggcggtgacggcaacgacatcctggaa	Protospacer
   ***.***** *************** . 

41. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP022363 (Azospirillum sp. TSH58 plasmid TSH58_p03, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gtccggcggtgacggcaacgacatcctggac	Protospacer
   ***.***** *************** ..

42. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP010598 (Phaeobacter inhibens strain P10 plasmid pP10_c, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gcgcggtggtgacggcaacgacaccctgtac	Protospacer
  .********* **********.****...

43. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NC_018288 (Phaeobacter inhibens DSM 17395 plasmid pPGA1_65, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gcgcggtggtgacggcaacgacaccctgtac	Protospacer
  .********* **********.****...

44. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP014527 (Haematospirillum jordaniae strain H5569 plasmid unnamed 2, complete sequence) position: , mismatch: 8, identity: 0.742

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gaccggtggtgagggcaacgacaccctgacc	Protospacer
 . *********.**********.****  .

45. spacer 3.2|53487|31|NC_018422|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 8, identity: 0.742

gttgggtgacggcggcaatgatgaactgcgc	CRISPR spacer
gccgggtgacggcggcgctgatgaaccgtct	Protospacer
*..*************. ********.*. .

46. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP048425 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.71

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gatgggtgatgaaggcaacgacatcctcaac	Protospacer
 .  ****.******************  ..

47. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 9, identity: 0.71

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gcagggtggtgacggcaacgacgtcctcatc	Protospacer
  * ******** *********.****   .

48. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP019311 (Phaeobacter inhibens strain DOK1-1 plasmid pDOK1-1-4, complete sequence) position: , mismatch: 9, identity: 0.71

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gcgtggtggtgaaggcgacgacaccctgtac	Protospacer
  ..************.******.****...

49. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP013536 (Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence) position: , mismatch: 9, identity: 0.71

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
ggacggtggcgacggcaacgacattgccttt	Protospacer
 ********.** ***********. . . *

50. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 9, identity: 0.71

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
ggacggtggcgacggcaacgacattgccttt	Protospacer
 ********.** ***********. . . *

51. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP013546 (Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence) position: , mismatch: 9, identity: 0.71

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
ggacggtggcgacggcaacgacattgccttt	Protospacer
 ********.** ***********. . . *

52. spacer 2.1|53223|31|NC_018422|CRISPRCasFinder matches to NZ_CP021372 (Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence) position: , mismatch: 10, identity: 0.677

cgacggtggtgaaggcaacgacatcctgcgt	CRISPR spacer
gatgggcgatgaaggcaacgacatcctcaac	Protospacer
 .  **.*.******************  ..

2. NC_018286

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1908155 : 1942975	32	Paracoccus_phage(30.0%)	head,capsid,tail,tRNA,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_018286|1908155:1942975|DBSCAN-SWA
CTCAGGTCTGCGACATCTCCGCCGTCGGCGGGATCAAAAGCGACGCATCGCCATAGGAAAAGAACCGGTATTCCTCGGCCAGCGCATGATCATAGATCGCCCGGATCCGGTCCTGACCCATCAGCGCCGAGACCAGCATCAGCAGCGTCGATTTCGGCAGGTGGAAATTAGTCATCAGCGCATCCGCCACATGGAAGGTGAAGCCGGGATAGATAAAGATATCAGTATCCCCCTCCCAGGGCTGGATCGCACCCGACTGCCCCGCACTCTCGATCAGCCGTAGCGCCGTGGTGCCAACCGGGATCACCCGCCCGCCTGCCGCCTTGGTCGCGGCAATCTCCGTCGCCGCCTCGGCGCTGACGCGGCCCCATTCGGCATGCATCCGGTGGGTGGTCACATCCTCCACCTTCACCGGCAGGAAGGTGCCCGCGCCCACATGCAGGGTGACATAGCTGATCTCGACACCCTTGGCCTGCAACTCCGCCAACAGCGCATCGTCAAAGTGCAAGGATGCCGTGGGTGCCGCCACCGCGCCGGAATTGCGCGCCCAGACGGTCTGATAGTCGGTTTTGTCCTGCTCATCCGCCGGTCGTTTGGCTGCGATATAAGGTGGCAGCGGCATTGCGCCGGCCTCCGCCAAAGCGGCATCAAAATCGGTACCACTCAGATTGAATTTCAGATGGCCCTGCCCGTCTTCAACCCGCTCCAATGTCGCGCTGAGCGCATCGGAGAAAACGATCTCTTCGCCCGGCTTGACCTTCTTCAGCGGTTTCAAAAGCGCCGCCCAGCTGCCATCCGCGCCCGGATCCAGCAGCGTGACCTCCACCTTGGCGGCCATCGGCCCCTGTGCGGTGTCGCGGTGACGCAACCCGCTGAGGCGCGCGGGAATCACCTTGGTGTCATTCAGCACCAGCCGGTCGCCGGACCGCAGCCACTGGCCCAGGTTGGCCACGCGCGCATCCCTGATACGGTCGCCTTCCGCCACCAGCAGCCGCGCGGAGCTGCGCGGCACTGCCGGACGGGTGGCAATGCGGTCATCGGGAAGATCGAAGTCAAAATCACTGAGTTTCATAGGCTGCGATATAGGCTGTTGCGCCGCCCTTGGCCAACAGGTTTTGTGCAGATAACCGCCAAACACTGCCCTGAAATCGGCCTCCGCCCCCAGGTCCGCCCCCCTAGCGATCTTCGCCGGGTGAGACGGAATAGGGCGGCCTTTCCCGCTCGGCCCGTGGCACCACGGTGCTGGGTGGCTCCTCCCCCGGCAGGCTTGGCGCCGGACCCCGAAACAGCTCGCGGAAGATCCCCGGTGCCAGCCCCGACAGCGGGTTCACCTGAACACGCGGATCATCCGCCGCCCCCTTCAAAGTGAAGGCAAAGCCAATCAGCCCCTCCCCCTTGCGGGTAAAGACCCGGCCAACCGCATTGAGCAGATAGATCGGAGAGATCACGCCCCGCATATTCAGAACACTGCGCTCCAGATCATAATTGCCATCCATCGACAGACCAATCGACGGCCCCACCGCGCTGCTTTCATGGACGATCAGATGGGTCGCCCCCAGCCGGAACTTGGCCTCAACCGTGGTGAACAGGATGCCCTGCCCCGCCAGCGCATCAATCAGCCCGACCACGCTCACCGCGTTCAGCAGCGCCGCCATGGATGGCGCGTCCTTAATACGGGTGTTCTTCACCTCAATCTGGCCGTCATATTCACCGGGCGCGCCGGGGGCGGGCACCAGCGACATATCAAACGTTCCGCCCGATCCATGGCGCAGCACGCCCGCCGCACGGAACACGCCGCCGGCATCCTGCGACTGAATCCGGGTGGCAAAACCGCCATCCTTGGGCACCACCACGCCATTGACCCCGGTTTGACCGTTCAGTGCCGCAGTAAAATTACCATTCAACCCTCCGGTGGTGGAAAACCGCCCGCGAAAGCCTGTCAGGGCAATGCTGTCTGTGACCTGCATTCGGTCCAGTTGCAGGGTGATTGGCCCGGTCCCGCCAGAGGACCCACCGCTGCTGCCACTGCCGCCCGATCCATCGGGCATCTGTCGCAGATCCAGCACACCGCTACGGATATTAATGCCCGGCGCCCGCGTACCGCGCCCGACCAGCTCAACCGCCCCCCGGAACCAGTTTCGCAATTCCACCCGATCAAACAACGCCCGGCTGAGACCACCCCCCGGCGCCAATGTCACATTGCCCGAGGCCTGCAACCCCGCCCCCTCCAGCGACAGCGCCTCCACCCGTGGCGTCTCTCCCAGAGTGGCGCGCATCCGCAGCTGGCCGGTGGTGGCTTCGCTCAACCGCCAGCTCAGCGCCGGGATCCGCAGGCCCAGCCCGCTCAGATCGCTCTCGAGCGTCAACTTCGGCGCCACGCCCTTGTCGATCACCACTTCATACCGGCCCACCCCGCGACCGAATACAGATCCCGCAGGCAGCCCGATATCAAACCTATCAACCGTGTCCTGCGACAGCTCAATCGTGCCTTTGACCCGCACAGGTGGCGCCTGACCCGCCGCCGCACTCGCCCGCTCCACTGCCGGACCGACTGCCTGCCGCCAGACAAGGCTGCCCGGCACCCCCGAAAGCGCCCCGTCCCCCTCAATCTGCACGTGGCCCTGATCCCCGCTCAGCCCCAGCACCTCAGCCGAGAGGCGCTCTCCCGGGACCAGCACATCACTGGCCGCGTCGCGAATATGCCCCCTGTAGTGATAGGTGATCTCCTCCGGTGTCACCCCTTTGCGCAGCGGCAGGGACAGCGTCCCGCTCAGCGCCACCTGTCCGGAGGCCAGATCCACCGGCAACCCCGCCTTGTCCATCACCGAAAGCGGCGGACGGTTGAGCAGCGAGAGCGCCGCCGTCACCGGGCCCGAGGCCTCAATCCGGGCGATCCCCGGCGCGCCGTCCTTCACCGAAGTGTCAGGAATGATGAACGACGTACCCGCCGCATCCACGCGCCCGCCCTGATCCGCCGTCACCCAGCCCTTTGTCGCCATCACCACCAACCGGTTGCCGTAAAGGCTGAATTGCCCGGCGGCCTCCCGCAGAGGGGGCAGCGATTTCTGGAATTTCACCGCCGCATCTTCAAAGGCCAGATCGAGATAGACGAAGGGTTTCGCCGTGCCACTGCCGCGCATGGCAAAATTCACATCCCGCGCATAACCACCCAACAGGTTCTCGCGCACCCATTCGCGCGGCTTTGGGGGCGCTGCGGCAGGCCAGACCTCTTTCAGCCGCTCGGCGGTCATCCGGTTGGCGCGTCCGTTCAGCGCGTAATCCCAACCCGTCTGCCCCGCCGAAATCTCACCATCCAGCAGGATCCGCGTCTCACCGTCGCGCACCAGCATCTCGCCCAGACGCAGCCGGAACGGCGCCATCTCCAGTTTAAAATCCGCCGTCACCCCGGCCAGATCCAGCGGCGTATCATAGAGTTTCGCCGGGTTGAGGCTCAGTCCCTGAAACCGCAATTGTCCGACCAGATCGGTCAGCTGGCCGTTTTCCACCCCGATCAGACGCGCCCGCCCTTCCATCGTGCCGGAGCCCCAGCCGCTGTTCACCGACAGCTCGTTGAAGCGCAGTTCCTGCCGGTCCGGCAGATAGGTGAAATAGCTCTGCGCGCCGGTGATCGGCACCGGGCGGGTGGCGGCGGTGGGCTGGATCACCCCTTCGCCAATCTGTAGGCTGGCAGAGACCGGCAGCAAGGCCCCCTCGCTGCTGATTGCGCCGCGCAGAGACCCCGAAATCGGCGCGTCCAGAACATCCAGCCAACCGAGTGCTGCGCTCTGGGCAGCGATATCCTTGCTCGCCACCGAATTGACAAGCACGCCAAATTCCGCCGCCTTGTCGCCGATCGCGGAGCTGTAATTCGCCTCAACAGTCCCAACGTAATCGCGCCCGCTCAGCAGCGAGAACCCGGCGGCCAGTTCAATATCCTGACCGCTGCGGTTCATGCGAATGCTGCCGCCATCCAGCGTCCAGACCCGCCCCAGACGCGCATCCTCATAGCGCAGGGTCAGCGCGTCGGTCTCAACCTCGACCAGCGCTGACAGCACCGGTAACTCCAGCTGGCGGTCCCATTGCTCAATCAGCGCAGGAAGGGTGGCCGCCTGCCGCAGCGGTGCCTCCCCCTCGGCCAAACTCAGTGCCAGACCGCCACTATTGTCCCGCCGCAGGGTTCCGTAAAGCCCGCTCAACATAATGGTCTTAGGCCGGATCTGACCGCGCAGCAGCGGCCGCATCGCCAGCGAGGCCTGCGCATCCGCCAACCGCGCCACCCGCGCGCCGGTCTCATCACGCAGGGTCACATCGCGCAGGCTGATGCGGGGCCGCCAGCCCCGGTTCACCACCAGATGAATAGCGCCGAATTCAATGCTTAACCCGCCCAGATGCCGCTCAATCCGCCGCTCCACCCGGTCACGCACCCAGTCTGGCGCGTCAAGCCGCGTCCCCAGCCCAAGGAAAACAACCCCGCTTGCCAGCAATGCCAGAACCACGGCGGTGATGGCTGCACTGCGCAGCATCCGGCGCAGGATGCGGGGCTTCGGCTTGGCTCTGACATCCGAAGCGGGTTGTGACACTGCAGCGGCCACTGTCTCTGCATCCTCGTCAGCAGGTTTGACGAGATCCCCGGCGGAAATGCCATCGGACGCCCGTGGCCCCGGAACCGGCACCGGCACCGCCTCGTCCTGCATTATGCGTTCCGCCTCGGCCTCTTCCCCTTCGGGCGCTGCGGTCACCTCCGGCGCCTCCTCATCCGGCCCCAGAAACCCCGGCCCGTCCGGCGGCGGCACCGCCTTTGCGACAGCCACACCCTCCGCGGCCACGGCCCCACTGGGCCCGGCATCCTGCACGGCATCCGCCGACGCAGAGGAAGATGGCTCCTGTTCAGAATCCACCGCTTTGGATGAGGCTGGTTTAATCCTTGCTTTCCCTTTGCCTGTGATGGCCTAACTGTGGCACGCAAACCCTGCGAAACCGTTTTGGAGACCTCGAATTATGCTCGCCCCCTCAGACCCCGCACCCTCCTTTAACCTGCCCCGCGATGGCGGTGGCACCGTGACGTTGGAGGAGCTGCGCGGCAAGGCCGTCGTGCTGTTCTTTTACCCCCGCGATGATACCCCGGGCTGCACCAAGGAATCCATCGGATTTTCCGAGCATCTGCAGGCCTTTGCCGATGCCGGGGCGGTGGTCTATGGCATCTCCAAGGATCCGGTCGCAAAACACGACAAATTTGTCGCCAAACACAGCCTGACCACGCCGCTCCTCTCTGATGCCGAAGGCACCACCTGCGAGGATTATGGCGTCTGGAAGGAAAAGAACATGTACGGCAAGAAACACTGGGGGATCGAACGCTCGACCTTCCTCATCGACGCCGAGGGCAACATCGCCCAGATCTGGCGCAAGGTGAAGGTCGACGGCCATGTCGCCGAGGTGCTCGAGGCCGCCAAAGCGCTCTGACCGCCCATTACGGCGGCCCTGCATATGCCCTTTGGCCGGGCGCAGGGCCGCCTATCCGCTTGCAGGTCAGCGCGCCCGGTGTCAGGGAATGGCCAACATCAGCCCAGCTCAACAGCCCACCGCCGAAACGGATCCGCGAAGATGACCAGCGACGCATCACAGACCAACGTAGACAGCCCTGACCGCCCGCTCAGCCTTGCGCAGATGGCGCAGCAGGTGCTGACCACCGCCGATGGGCGTGAGAAAACCGCCCTGTCGCGCCGCCATGCCGCGCACTGGTTTTCCTATCGCGCCGGTGATGCGGCAAAGATTGAGGTCGGCACCGCCAGCCCGCCGCTGCACCCCGCGCGTCCCGATAAGCCCGAACTTCTGAACCCGCGCGATGTGCCCCGTCGTCGCCCCGGATCCGAGGCCGGACGCAAGGCGCTTTTGCACGCGGTGGCGCATATCGAACTGAACGCGGTTGATCTGCACTGGGACATCATCGCGCGGTTCTCCCATGTGCCGATGCCGCTCGGCTTTTTTGACGACTGGGTTAAGGCGGCGGATGAAGAATCCAAACATTTCAACCTGATGTGCGACTGTCTTGAAGCCCTGGGCAGCTACTACGGAGAGCTGCCTGCCCATATCGGCATGTGGCGCGCCGCCGAAGACACCGCCGAGGATCTGATGGGCCGCCTCGCCGTCGTGCCGATGGTGCTGGAAGCGCGCGGTCTGGACGTCACCCCCGGCATGATCGAGGTTTTCCGCAAGGCAAAGCTCACTCAGGCGGTTGACGCGCTGGAGGTGATCTATGCCGAGGAGGTCAGCCATGTGGCCTATGGATCAAAATGGTTCCACTTCCTCTGTGGGCGCGACAATCTGGACCCGAAGGAGGTCTTTCATGATCTCGTCGGCAGATATTTCCACGGCCATCTGAAGCCGCCCTTCAACGAGGAAAAACGCGCCGAGGCCGGGATACCGCCGGATTTCTACTGGCCGCTCGCCGACGAAATCCCGGTCAAACCCCCGGCCCTGCGCTAGGCCTCGCCCAGCCGGGTCTTCAGCGGTCAATTCCGCGCAACCTTTGCCCGCCACAGATAAAATCGGCCTGCCTATCATCGGCGGGCCGCTCTTTATCGCACGCACCGGCACCCTGCCTGCGCCGTCATGATCCCGCCAATCCCGTCAGATATCGGCGAATTTTCGCTCATTTCGCAGCTGATCCCCACAGCTGCCGCGCCGTTTCCGCGCGGACCCGCCGAACAGCGGGTCAACAGGCTTGCCCAAACCCATCCGGCTGGCTATTCCCTTTCGCCATGGCGCGCTAACGCGGCCTGGCACTGCAGCAGGGCAGCTCCGATGGGACCGGGTCTGGCCAGAAGAAACCGGCAGGAGGAGCGCCGGTGACTGCAGCGCCGCAACTGGGGCAGGACTAAGGACCAAAGCGTGCGGACACGTCTGGCAATCAAAATTCACGCATTTCTCGAACGCCGGTTTCCGGAACGGCGGGTGTTCCTCAAGTCTGACTCAGATACACGTTTCATTCGGCTCCGGTCCGAAACCCAGCTCATCGCCTTTGCGGGTATGGCGCTGCTGGTGGCCTGGTCCATTGTTGCCACTGCGATTGTTCTGATGGACAGCATCGGCTCCGGCAATTTCCGGGAGCAGGCCAAGCGCGATCAGATGACCTACCGCGCCCGCCTGAATGCGCTGTCAGGCGAACGCGACGATCGCGCCGCCGAGGCGCTGGCCGCTCAGGAACGGTTCAACGCCGCCCTGACGCAGATCTCCTCCATGCAATCGGAACTGCTCGCGTCAGAGACCCGTCGCCGCGAACTCGAAACCGGTATCGAGGTGATTCAGACCACGCTGCGCCAGACCATGAAGGAACGCGAAACCGCCCGCGACGCGCTGGTGGCGCTGAAGCAGGAAACCGCCGCCGACAGCCCCGCCCAGATGATGGCCGTCAGCGCCCCGGTTCAGATGGAATTCATGGCCGACGCGCTGGCCGAAACCGCCGCACAGCGCGACCAGATTGAGGCCAACGCCCAATCCGCGCTTGAGCAGCGCGACGCGCTGGAACTGGAACTGCGTCTGCTGGATGAACGCAACGACCAGATTTTCCGCCAGCTGGAAGAGGCGATGGAAGTGTCTGTCGCACCGCTCGACAAAATGTTCCGCAGCGCCGGAATGCCCACCGACCGTATTCTGGAACAGGTACGGCGCGGATATAGCGGTCAGGGCGGTCCGCTCAGCCCTTTAGCCCTGTCCACGCGCGGTGAGGAACCCACCCGCGAGGAGCTGCGCGCCAATAACCTGCTGCATCAGATGAATCAGCTGAACCTCTATCGGCTGGCCGCGCAAAAGGCGCCCTTTGCCTCGCCGGTGAACCTCAATCTGGTGCGCCGCAGCTCCGGCTTCGGCTATCGCCGTGACCCCAAAACAGGTGGTCGCCGCCTGCACAAGGGCTCCGATTTCGCTGGCCGCACCGGCACCGATATCTTTGCCACCGCTGATGGGGTTGTGACCCATGCGGGCTGGCAATCCGGCTACGGAAAACTTGTTACAATTCAACATGCCTTTGGCATTGAGACGAAATATGCCCATAACTCCAACATCCGCGTCAAGGTCGGTCAAAGGGTCTCGCGCGGCGATCACATCAGTGATATGGGTAACACCGGACGGTCCACCGGGACCCACCTCCACTACGAGGTTCGGGTCAATGGCAACCCCGTAAACCCGATGATCTATATCAAGGCTGCGAGAAATGTTTTCTAAGAGCAAAATCAACGAGCCCGGCCAGAAAGCGGCCGAAGCAACTCCTGCGGCGCCTGCGCCGTCTTCCGCTCCGGTTCCGCCCGCCAGCGATTTCAAGGCAACCGCCCCCAAGGCGAAGCCGCCGGCATCCGTGCTCAGCTCGGATCTGCACATCACCGGCAACCTCAAGACCACCGGTGACATTCAGGTCGAAGGCACCGTCGAAGGTGACATCCGGGCCCATCTGCTGACCATCGGCGAGAGCGCGACCATCAAGGGCGAAGTGACTGCCGATGACGTGGTGATCAACGGCCGTATTGTGGGCCGCGTGCGCGGCCTGAAGGTGCGCCTGACCTCGACCGCCCGCGTCGAAGGCGACATCATCCACAAGACCATCGCGATCGAAAGCGGCGCCCATTTCGAAGGCTCCGTTCAGCGTCAGGACGATCCGCTGAACCCCGGCAAAGCCGCAGCGCCCCGCGCCGCAGCCCCGGCACCAGCCCCCTCAGCCGCCGTCACCGCAGCCACCGCGGCACATAAATCCGAAGGCTGATCCCACAGCTGCCCATTCAGGCAGCCAAGAATAGCCAAACGCCGCAGGTCACCCCCTGCGGCGTTTTTTGTGTGCTGCGCACGTTACGTTACTGGCAGGCAGAGCGAACGCAACGTCGCATATGGAGAGTGCGCAACCTGAAACACTGGGCCTTGCACCTATAAGTTGCTGAATGTAGGAAATGGGTAAATTTGCATGCATCATGCGTGCCGCCCTCACAATCAGGACATATATTTTCGACAATGGCTATTTTCACCGTAAATGACCCGACAGGCACGCTGTCGCTGAATAACCTCGGCGACCTTGGCTTTGACAACATCAGCCTGAACAGCCGATCGGTCAATCAGTTGTTTTTTACCAGCCCCACTGGCACCAGCATCACGCTGACTGGGGATTTTTCATCTTCATCACCCTATTTTTGGACGATTGAGTCGATGGCGGTTAACTCCGGTGGTACACCGGTCTACGCAATCAGTGAGTTCTCAATGAACTTCTATCGCTTCAGCGCCAGCAGCGGCGCTGCCTTGGAAGCAGCCATTCTCACAGGTGATGACACAATCACCTCGAATATGGCCGAAGGAACCCGCTGGCTGGCCTACGGCGGTGATGACGTCATCAGCCTAGGTATCGGCGATGACTACGTCCACGGAGGGTACGGCACCGACAGGCTGATCATTCACGACACTTATGGCCGGGCGGACATCTCCTCGGTCTACGGTGGCGTGTGGATCGACTCTGCCGACGGGAGAGATACCCTGCTGTCGATCGAACAGCTGCAGTTCAGCAACCGTAGTTTTTCCCTGAGCGTGGACACCAGCAGCAGCACCTCAATGAGCGGCGATCGCGACAACACCCTTACCAGCGACATCATGCTGGGCGGCCTTGGCGCTGACACTTTGGCCGGGCTCTCCGGGCGCGATATGCTGCTGGGCGAAGAGGGGAACGACCACCTGATGGGCGGCGAGGGCCACGACACATTAAAAGGTGGCGATGGGCACGATATCCTCCTGGGTGGTTCCGGACGGGACTGGTTGGCCGGCGACCTCGGCGAGGACGCCATCAGCGGCGGTTCTCACGGTGACAAGCTCATCGGCGGTGGTGGTCACGACACTTTGCGCGGACAGGATGGTCACGATGTACTGCGCGGCAACTCCGGCTGGGATCAGCTCCTGGGCGGGCGCGGCAATGACCGCATCTATGGCGATGGCGGGCAGGATCGGCTGATCGGCCAAGAGGGCAATGACACCCTGACCGGCGGTGCTCATGCCGACACATTTGTCTTCCATCGCGGCTATGGCACCGACATCATCACAGATTTCACCGTCGGCGAAGATCGGATCCAGATTGGTCGCGGGGCTGACGGGACCGATGATCTGACCTTCACCAGCCAAGGCAATAGTGTTCAGATCACTTTTGCCGATGTCACCATCATGGTGGAGAACAGCACGCTGGCGCAGATTGAGGATGCGGACAACTTTCTGTTCTGAGCCTCATCTTTGCTGAGGCACACTGTTTACCCGAGATCACAGGCGTATCCCGCAAGGGATGCGCCTTTTTCCTAACTTTTGACGGCACAAACACAGATCCGGGTGTGAAGAATTTGCGCAACAGGCTTAACAAAGGTTAAGAATTCATTAACGACAACCTTCCCAGACCAAAACCTCCCGCCTAGGCTGACCGCAAAAGCATCGAAAAGATGCGTCAGGCATTCAAGCAGTAGGTCAGACCATGGCAGAACTTCTCGTCACGGCTGCGTCAAATGTGGCGCCGCCGTTCGATTTCAGTGACTTCGATTTCACCAAGGTCGCGGTTCTCAGCGCCACGGACACCCAGATCGCGGTGCAATATGGTGCCTTTGTCATGGTGTTTCAGGGCAGCTTCAGCTTTGACGAAAGTGGCAATCTGAGCCCCGACAGCCCGCTCAATGGCTTTGGCCTGTTTTATGACCAGTCGCTGATCATGTCGGTGAGCGGCTTCACCCTGCCCTCGCAGATGATTGCGGATGGGGATCTCTACGCGCTGCTGGCGGTGGCCCTCTCCGGGGATGACATCATCACCTCTGCCTGGAACGGCGGCGAGCGGATCAACGCGTTTGCCGGCAATGACACCATTCGCGCCGGTAACGGCGATGACACCATTTTTGGCGGCGCCGGTCAGGATGAGCTGGTTCTGGGAGACGGTGTTCACACCTACAGCTTCGCCTTTGACGACAGCGCCGGGGCGCTGCTGACCACCACCAAGGGGCGCGACATGCTCTTTGATGTGGAAACCGTCCGGCTCGCCAACCAGACCCTGCATATTCAGGAAGGCAGCGCCACGGATGAGGCCCTCCACAGCACCAATGTCGATGACACCACCCGTTCTGACATGATCCATGGCCGCGGCGGCGACGACACGATCACCGGCGGTGCGGGCAAGGACTTCCTGCTGGGAGGCGCCGGGGAAGACAGGCTCTCCGGGGGAAAAAACGACGACTTCCTTGATGGCGGGCTTGATGATGATCACCTCTCCGGCAATGCAGGTGATGACAATCTGCGCGGCAGCCTCGGCAATGACACGTTGATCGGCGGCGCGGGCAATGACACGCTGCGCGGCGACAATGATGTGGGCCCCGATGACAACGCCGATGACCTGTTGATCGGCGGCAGCGGCCACGACAGCCTCGACGGCAACGCCGGCAATGACACGCTGAAGGCCGGCAATGGCGCCGATACGCTGCATGGCGGCGAAGGCGATGACATCCTCAATGGTGGACGTGGGCGCGATTTGATCACCGGCGATGACGGGCGCGATACTCTGGCCGGGGGGCGCGCCAATGATACGCTGACCGGAGGCGCCGGCAACGACCGGCTGAGCGGCGGCGCAGGCCATGACGTGATGCGCGGCGATGCAGGCAACGATCTGCTGATTGGCGGGCGTGGCCACGACACCTTGTTTGGCAGCGATGGGGCCGACCGGCTGATTGGCCAGTCCGGTCATGACCGTCTGACCGGCGGCAGCGGCGGCGACAGCTTTGTCTTTGCCCGCGGCTCCGGCCGTGACACCATCACCGATTTCCAGCTGGGTGAGGATCTGATCCAGATCACCCGTGGCGCCGACCGGATCGACCATCTTGGGTTTGCACAGCTGGGCGCGGATGTGCGCATCACTTTCGCCAATGTCTCGATCCTGGTCGAAGACGTGACCGTCGACCAGCTGATGAATACCGATAACTTCCTGTTCTGATCAGTTACCGCTCTCAGAATATGGCCTTGGGCGCGCCTTTGTCGGTGCGCCCATTTTTTGTACAGAACTCAGCTGAGCGCCGCCCCCTCACTCCAGCATCCAGTCCCCCTTGGGCCAGAAGGCGTGATAGGCAAAGGCAAACATCACATCATGGGGCAGATCCGCGCCATTACGCCCCTGCACCCGCACCGATCCCACATCGCGCCCCTTGCCGACGTGTCCTGCATCCAGCGCCGAGGCCTGCCCGGCCCGCCAGCTGAGGATCACCCCGGCCTCGCGGATTTCCCCGGCCTTGGCCAAGCGCGCCAAGGGCCAGGCCCGATCCCCCACCCGCACCACACGCGCCAGCGGCGCGATACCATGGGGCGGTGGCGCGCCATCATAAAGAAACGGCCAATTCGACCGGTCATAGCCCTGATAGGGATTGCGCCCGTAACTGCGGTTGTGGCGCGGCTCGGCCATCACCAACCCCTTTGGGTAGGCGGCCTGAAATCCCTGCCAACTGTCCAGCCAGCTCGGCAGTTGCCGCAGCTCCCGGCCAGTCATCTCGCCCACGATGCCGGTGCCGGTGGCCTGCTGCCACCAGCTCTCGCTCTCGCGGTCATACATTACCATATCGGACTGGCGCAGCTTGCCGGTGACACCAAAGCTCAGGGTGCGACCAGCCACCCGCCGGTCAAAGCTCATCGCGGAATTGCACAAGGGGCAATAGGTGATTGCCACCGGGGTGTAGCCCACCCGGTCATTGACGATTTCATGCCAGATCAGGTAGCGCAGCGGATAGGCATGCGCCGCCTGCCCCGGCAGATCCAGCACCACAACCGGCTCGGCGGGGCTCAGCCCCTTCACCTGCGCGGCAGGGTGAAACGCTGGATCGCTCAGCGCCGGAATGCCATCCTTTGGTGGGCCACCGGATTTGATTTCGCCCCAGTCCGCAACAATTGTGCGGCTGAAATCCGTTGTCGGCCACTCGCGCGACCAGATAGCCGGATCTGCACGAGCCGCCGCCAGCCATGGCAGCATCAACAGCAGCGACAACGACAGCACCGCCACCGCCCGATTTTGTACTCTGGATATCCCTCTCCTGACCGCCTGTGACATCGCTGGCCTCCTTCCTGTACCCCACAGATGATGGGTTCCCCGGCCCAAATCAGGGGGCACAGCTTGCCGCAAACCCGCCTCACATGCACCGCACAAGCCCGTGACAGGCGCCCGTGTCCTAGGCGGAAAACAGCAAACGGCCCGCACCATTCAAGGTACGGGCCGTTCGAACAATGACCTGCGGATCACAAGATCACGCGAGGCAAGGCTCACTCGGTTACAGAGACCGTTTTCATCACGTCAGGCTGACCGACAACGGCGCCGTTCTGACTGCCGCTGCCGCGTTTGATCGCGTCGACCACATCCATGCCCTCGGTCACCTTGCCCACAACGGTGTACTGACCGTTCAGGAAATGCCCCGGCGCAAACATGATGAAAAACTGCGAATTGGCGCTATCGGGATCCTGCGAGCGGGCCATGCCGACCACACCGCGATCAAACTCCAGATCGGAGAATTCGGCCGGCAGGTCCGACCGCTCGGAACCGCCCATGCCCGCGCGGCGCATATCGCCACCCAGCTTGCCAAATTCCACATCGCCGGTCTGCGCCATGAAGCCTTCGATCACGCGGTGAAAGACCACGCCATCGTATTTGCCTTCAGCCGCCAGCGCGGTGATCTGCTCGACATGCTTGGGGGCCACGTCCTCGAACAGGTCGATCTTGATGGTGCCATTGGCGCCCTCACCCTCAACCGCGATCTCCAGACCGCTGGCCAGTGCCGGACCCGCCATCAGCGCAAATACCGCTGCCAGCTTATACATCGGCTGCCACCTTGACGCTGACCATGCGGTCAGGGTTCGCAGGCGGCTCACCCCGGGTGATCGCATCGACATGCTCCATCCCCTCGATCACGCGGCCATAGACCGTGTACTGACCGTTCAGGAAGTGGTTGTCCTTGAAGTTGATGAAGAACTGAGAGTTGGCCGAATCCGGGTTGGCGGAGCGCGCCGCGCCCAGCGTGCCACGGTCATGCGGCAGCTTGGAGAATTCCGCCGGAACATTCGGCAGATCAGAGCCACCGGTGCCCGCCATACGCAGGTTGAACCCGTCTTCCATGTCGCCGTGCTGCACGTCGCCGGTCTGCGCCATGAAACCATCGATCACCCGGTGAAACGCCACATTGTCATATGCGCCGCTACGGGCCAGTTCTTTCATGCGCGCGCTGTGCTGAGGGGCCACGTCGGGCAGCAGTTCGATCACCACCTTGCCGTCTTTCAGCTCCATGATGATGGTGTTTTCGGGGTCTTTGATCTCGGCCATGTGGCGCTCCTGTTCTTTGCATTTGCCCGATAGTTAAGGCCAGCGCCCGCAATTGCCAAGGGAGCTTTGGTCACAGAGCATTGACTGAGCGGCAAAAAGCCCCGAAACATCGCGCCAACACCGCCAGCGGCACAGTTTCCGCCGCTGGCGCATCAAACCAAGACCAAAGAAGGATATGATCATGGGCTGGAACGCACTCGACACGATGGACCTGGCAGGCAAGCGCGTTCTGGTGCGCGTCGATATCAACGTCCCGGTTGAGGATGGCCGGGTCACCGATGACACCCGCATCCAGCGCGTCGCCCCCACGATCAAGGATATCCTCGCCGCAGGCGGCACTCCAATTCTGCTGGCCCATTTCGGCCGTCCAAAGGGCAAGGTCGTCGCAGAGATGTCGCTACGCCCGCTGGTGCCGGCACTTGAGGCCGCGTTCGGCGCCCCCGTCACCTTTGCTGCGGATTGCCGTGGCCCCGCTGCCGAAGCCGCCGTTCAGGGCCTGCCAGCCGGTGGCGTGCTGCTGCTGGAAAATACCCGTTTCCACGCGGGCGAGGAAAAGAACGACGCCGATCTTGCCGCTGAGATGGCCAAGCTGGGCGATATCTACTGCAATGATGCGTTTTCTGCCGCCCACCGCGCCCACGCCTCGACCGAAGCGCTGGCCCGTCTGCTGCCTGCCTGTGCTGGTCGTCTGATGCAGGCCGAGCTGACAGCGCTGGAAGCCGCCCTTGGCCAACCCCAGCGCCCGGTGACAGCCGTCGTCGGCGGCGCCAAAGTCTCTACCAAGCTCGAGCTTCTGGGCAATCTGGTCGGCAAGGTCGACAATCTGGTGATTGGTGGCGGCATGGCCAATACCTTCCTCGCGGCACAGGGCATCGACGTGGGCAAATCCCTCTGTGAGCATGATATGGCCGACACCGCCCGCGAGATCCTGAGCAAGGCCGAAACTCAGGGCTGTAAGATCATCCTGCCCATCGACGTCGTGGTCGCGCGCGAGTTCAAGGCAGGTGCCGACAATGAAACCGTCGCCGCTGACGCCTGCCCCGCCGATGCAATGATCCTGGACGCAGGCCCGCAGACTGTCGCTGCCGTCGCCGATACGCTTTTCGCCTCCAAAACGCTGATCTGGAATGGCCCGATGGGCGCCTTTGAAATCGCGCCCTTTGATGCTGCCACCAATGCCGCTGCACAACAGGCCGCCAGCCTCACCAAATCCGGCGCGCTGGTCAGCGTGGCAGGCGGCGGCGACACCGTGGCCGCCCTCAATCAGGCCGGGGCTGCGGCTGATTTCACCTATATCTCCACCGCGGGCGGTGCCTTCCTGGAGTGGATGGAGGGCAAGACCCTGCCCGGCGTTGCCGCCCTCGAAGGTTGAATCAGCCGCGCGGTCTGTCGTCGACCTGACGCCATCGCTGCCGTAAAAAGGTTAAGATCGCAGCGATCCGCAGAGCGCATTAACCATCCGTTTACCATTTGCACCCCTGCCACGCGGTTGGGGTGCGGTTTTGCCTGAGAATGTTCAAAATTAACAATTTTTACGTTTCACAAACCATGTTGCCTGTGGCAGTATTGTTGCAGACGCCGGGCAAACTGGCGCGAGACTTGAGCAGCAGATCATACAGGCTATCCACCGTGACCCGAAGCAACCGACCCTCTCTGGGCGCATTCGTTTTCTCAACGATTGCATTCGCACTCAGCGCATATTTTACCTTTGCCGCCGTGCAGGGCGACTTCGGGTTGTTCAGGCGGGTCGAGATCCAGGCCGAGGCCGAAGCGCTGCGTCAGGATCTCGACCAGCTGAAACGCGAAACCGCGCAGATGGAAAATCTCACCCATCGGCTGTCTGATGACTACCTCGATCTGGATCTGCTGGATGAGCAGGCGCGCTCGGTCCTTGGCCTGCTGCGCGCCGATGAGATTGTCATCCGCTAACGAGCCCAGCCAGCAGACCACAGTCATCGATGTGTCACCGCCCGCAGCCCCGCTTGCGGGCGTTTTGTCATGATGAGGGAACGCAGCGCGCCCTGCCCGCCGCTTGCCATTTCGCCCCCAGCGCAGACGCCTCTTAAAACCGGCATCTGGCTTGCCACCTTTCCCAACGTTACCCCCGGAAAACGCCATCGCCTTTACCCCTTGGTGACGGCACGTCATAATAACACTCGCATGACGTCGTAAAATCCATTATGAACTAGTTTAGCATTAAACTATCTAGCCTTAAGGGGGAGCCCGCCACCATGGCTGCGAGAAAAAGTGTCAAGAAACCAAACGTTTCTGCTGATGAGCTGCTCGAATACTACCGCGAGATGCTGCTGATCCGGCGATTCGAGGAAAAGGCCGGCCAGCTTTACGGCATGGGCCTGATTGGCGGCTTCTGCCACCTCTATATCGGTCAGGAAGCGGTTGTTGTCGGTCTTGAGGCCGCCGCAGAGGACGGCGACAAGCGTGTCACCTCCTACCGCGACCACGGCCATATGCTGGCCTGTGGCATGGACCCCAACGGCGTCATGGCCGAGCTGACCGGCCGCGAAGGCGGCTACTCCAAGGGTAAGGGCGGCTCGATGCATATGTTCTCCAAGGAGAAACATTTCTACGGCGGCCACGGCATCGTCGGCGCGCAGGTGCCACTGGGTGCAGGCCTCGCCTTCTCTGACAAATACAAAGGCAACGACCGCGTGACCTTCGCCTATTTCGGCGATGGCGCGGCCAACCAGGGTCAGGTCTACGAGACCTACAACATGGCCCAGCTCTGGGATCTGCCGGTCGTCTTCGTGATCGAGAACAACCAATACGCCATGGGCACCTCGGTGCAGCGCTCCACCAAATCCCCCGCCCTGTGGAAACGCGGCGAAGCCTACGGCATCAAGGGTGAAGAAGTGGACGGCATGGATGTGCTGGCCGTGAAAGAGGCCGGCGAACGCGCCGTCGCCCACTGCCGCGCAGGCAAAGGCCCCTATATCCTTGAGGTAAAAACCTACCGCTATCGTGGTCACTCCATGTCCGACCCCGCGAAATACCGCACCCGCGAAGAGGTGCAGAAAATGCGCGAGGAACGCGATCCCATCGAACAGGTCCGCGACATGCTGCTCACCGGCAAACACGCGACCGAGGATGACCTGAAGGCGATCGACAAAGAGATCAAGGACATCGTCAACAAATCCGCAGACTTCTCCAAAGAGAGCCCGGAACCGGCGCTCGAAGAACTCTGGACCGATATTTATGCGGACGATCTGCCGCAAGAAACCGCCTGAGGGGACGTAACACGATATGGCAACTGAAATCCTGATGCCCGCCCTGTCGCCGACCATGGAGGAAGGCACCCTGGCCAAATGGCTGGTCAAAGAGGGCGATACCGTAAATTCCGGCGATATTCTGGCCGAGATCGAAACCGACAAGGCGACGATGGAATTCGAAGCCGTTGACGAAGGCGTCATCGGCAAGATCCTGATCGGTGAAGGCAGCGAAAACGTGAAGGTCAACAGCCCGATCGCCGTGCTGCTGGAAGAGGGCGAAAGCTACGACCCCGACGCGGCCCCCGCAGCATCCGCGCCCTCCGCAAGCGAAGCGCCGGCGGCAGAGGCACCTGCGGCGCCCGCAACCACCGCCGCTGCTGCCGCGGCCCCCGCCGCACCGGAGGTGGACACCACCCCCGACTGGCCCGAGGGCACCGAGGTGGTGCAGACCACAGTCCGCGAAGCCCTGCGCGACGCCATGGCCGAGGAAATGCGCCGCGACGATGATGTTTTCCTGATGGGCGAGGAAGTCGCCGAATATCAGGGCGCCTATAAGATCTCTCAGGGCCTGCTGGACGAATTCGGCGCCAAGCGGGTGATCGACACCCCGATCACCGAACATGGTTTTGCCGGCATCGCCACCGGCGCGGCCTTTGGCGGTCTGCGCCCGATTGTGGAATTCATGACCTTCAACTTCGCCATGCAGGCGATTGACCACATCATCAACTCGGCGGCCAAGACGCTCTATATGTCCGGCGGTCAGATGGGCGCACCGATGGTGTTCCGTGGCCCCAATGGCGCCGCCGCCCGCGTGGGCGCACAGCACAGCCAGGATTATGCCGCCTGGTACATGCAGATCCCCGGCCTGAAGGTGGCGATGCCCTACTCCGCCTCCGACGCCAAAGGTCTGATGAAAACCGCAATCCGCGACAACAACCCGGTGATCTTCCTCGAGAACGAGATCCTCTACGGCAAATCCTTTGAAGTGCCGAAGCTGGATGATTACACCGTTCCCTTTGGCAAGGCCCGGATCTGGCGGGAAGGCACTGACGTCACCATCGTCTCCTTTGGCATCGGCATGACCTATGCGCTGGAAGCGGCGGAGAAACTGGCCGAGGATGGCATCAGCGCCGAGGTCATCGACCTGCGCACCCTGCGCCCGATGGACACCGGTTCCATCATCAAATCGGTGATGAAGACCAACCGTCTGGTTACAGTTGAAGAAGGCTGGCCGCAGGGCTCTGTTGGCAGCTATATCTCCTCCGTGGTGATGCAGGAGGCGTTTGATTACCTCGACGCCCCCGTCATCACCTGCACCGGCAAGGACGTGCCCATGCCCTATGCCGCCAATCTCGAAAAACACGCGCTGGTCACCACAGATGAGGTGATCGAAGCGGTGAAACAAGTGACCTACCGGTAAGGAGAGACAGCGATGCCCACCGAAATCCTGATGCCCGCCCTCTCTCCCACGATGGAGGAAGGCACGCTTGCCAAATGGCTCGTGAAGGAAGGCGACACCGTCGCCTCCGGCGACCTTCTGGCGGAAATCGAAACCGACAAGGCGACGATGGAATTTGAGGCCGTCGACGAAGGGGTGATCGGCAAGATCCTGATCCCCGAAGGCAGCGAAGGTGTGAAGGTCAACAGCCCCATCGCCGTGCTGCTGGAAGAGGGCGAAAGTGCCGACGACATCGGCACCACCCCGTCTGCCCCCGCAGCCGCGGCAGACGAGGCCGCCCCTGTGGCGCCCGAGGAAGCCGCCCCGGCCTCTTTCCCAGCTCCGGCAGAGGCCCCCGCTGCGGCAACACCCGCGCCCGCAGCCCCGCAGGGCGCCGATGGCAACCGCATCTTTGCATCGCCTCTGGCGCGCCGTATCGCGGCTGATAAGGGGTTGGATCTGGCCCAGCTGAACGGCTCCGGCCCCCGTGGCCGCATCGTGAAGGCCGACGTGGAAAACGCCAAACCGCAGGTCGCCGCCGCCCCGGCAGCAGCCGCTCCGGCAACCGCCGCAGCCCCTGCCGCAGCTGTCTCCACTGGTCCCTCTACCGATCAGGTCGCCCGCATGTACGAAGGCCGCACCTATGAGGAGGTCAAACTGGACGGCATGCGCAAGACCATCGCCGCCCGCCTCACCGAAGCCAAGCAGACCGTGCCGCATTTCTACCTGCGCCGCGACATCCAGCTGGATGCACTGCTGAAGTTCCGCGGCGAGCTGAACAAACAGCTGGAGGCCCGTGGCGTCAAACTCTCGGTCAATGACTTCATCATCAAGGCCTGTGCCCTGGCGCTGCAGGCCGTGCCGGACGCAAACGCCGTCTGGGCCGGGGACCGCGTGCTGAAGATGGAGGCCTCCGATGTGGCGGTCGCCGTCGCGATTGAGGGCGGCCTGTTCACGCCCGTCCTGCAGAACAGCGATACCAAATCGCTCTCGACCCTGTCGACGGAGATGAAAGACCTCGCCAAACGCGCCCGCGACCGCAAACTTGCGCCGCATGAATATCAGGGTGGCAGCTTTGCGATCTCCAACCTCGGCATGTTCGGCATCGACAATTTCGACGCCATCGTGAACCCGCCGCACGCAGGCATCCTCGCCGTGGGCGCAGGGGTCAAGAAACCGGTTGTCGGTGCAGACGGCGAACTGGCCGTGGCCACCGTGATGTCGGTGACCATGTCCGTCGACCACCGCGTCATCGACGGCGCACTTGGCGCAGAACTGCTGAACGCGATCAAGGACAACCTCGAAAACCCGATGATGATGCTGGCCTGAGCCCCGTAAATCAACGGAGATATAAAAGGGACCGGGGCATTGCTCCGGTCCCTTTTATACGGCTCGGGTGTTGGGTTGACTGCGCCTGTGTAGATGGCCCAAGAGGGCACCCGCGATAGACCTCAGGCAAAATCGAGTGTGCACCAGTATCCGAAGCGCGCAATTTCCGGAGTCGCTCTGCCTGCAGCGACCGAATATCATGCAATCTCTGCTAAGTGGGACGAAGCGCCAATTCGCTGCGTTTGAGCCAATGACAGCTCTTGAACACTAGGGCTCGTCAAAGATCCAATAGTTCTTGCGTATCGGCCCTACGGGAGTGTTATTGGTCGACATGCTTCTATATATTTTTCTTGGATTTCTCATCGGGTTTGTACTTTCTCTGCGGTTTATTCGAAACCCGCGCAAAGCTCTCAACTGGGGAGTAATATTGGGTGTCGTCCCTTTGGTTTTGCTGCTGGGACCAGCCAATGCTCCTATGCAGGGCATTGGTTCGGTTCTGAACTTTGCTTTCTTCGCGCTTGGACCCATCATGCTAGTTCCATTTGTGGCAAGCAGCGCTCCACTCGGCATGGCTGGCGCTTCGATTGTGTTGTGGATCGGGCACCAGCGACCAAGGTGGGCCTCATGGGCAACTGGGGTTGCAATCCTGGGGCTGACAGTATCGGTAACACTTTTGCCAGTCGCGCAGCGTGAAATAGCAAAGCGCCATTTAGCTGAGGATCAAGATGTTCGGGCCACAGAAATCATCCGCGCGGATTTCACGGGCACCTTGGCAGAGCATCAGGTTGCTTTTCCAGCGAGTCCTCGCCTCCGCGTATTCGACGGCTGTGCGCCGGATGTTCAAGCTGGGCTATTCGGATGCTCAACAAACCTAACCAACCCCGTTTCCGGTTTCACTAAGCCAAACGACGTACTCCTGCATGAACGTCGCGACCCTATCAATTTTCGAACCATCAGAGTTTCACCTGTAGAGCATGACTGTCGCCTAGGAAACGACTACTGCCTCACACAAGAAAAAGTGGATCATTGGTGTCGCGAAACCCGCCCAGATCAGGCCGATAGTATCTGGTGCCGCGACATACCGACGATGCAATTTGAACTACGTAGAGATGCGACGCCTGGCCCATCTGACCGAGACGAACCGGAACTGACCGCACAATACTCTGACACTGCGCTCGGGCCTGGACGGGTCACATGTTTCTATAGCCCCGACCCGGCCGAAACTGACAGGCAAGGCGTAACCTGCCGTCTTGTTTTCGAGTTAGCGAATAGAGTAAGCGCCACCCTAGGCGTTCGCCGTGAGCAAATAACTGCAGGCGATCCGGAATTGATTAAAACGATTGAGTTGATCCCTGATTACTGGGCAAGTTTGACGGAAACTCGCTAGCGAACCTTTGTTGGGTCTGCAGCATCGGGAACTATGGGCTCACTGCCGACTTGCGGCGGTGCGACAGCAGGGTTGCAGCGATACCGCAACTCGTCGCAGCCGCTCGTTGATCGCAGCCAGCCCAATCACACCATTCACTCCGAGTGCAACATCGCGAACGGGGCTGACACGAGGGCCGCATTATGACGTCCCGGCCACCGACGAAAAACGCCGATAGCAACAGCCCTGCGATTGACTGCACACCTCCCCCACCCCACGAAAAAAGGGGCCGCCAGCGCCGCCCCTCTCCCTCGTCATCTTTCCAAAAATACTCACAAATGCACCAATGGCGGCACGCGCATCGCCCGCCATGTTCAGACCCGCAGAGCGGCGCGGCCTATTGCGGCTTGCCGCCTCCCAGCACCTGATTCATGCTCACTGACGGCTGATCGCAGCCTGCCTCGCCGACGATCTTGGCCGGCACGCCCGCCACGGTCTTGCAGGGCGGGATCTCCTGCAGCACCACTGATCCGGCCGCAATGCGGCTACAATGGCCGACCTTGATGTTGCCCAGAACCTTGGCACCGGCCCCGATCAGCACACCATCGCCGATCTTCGGATGGCGATCTTCCTCTTCCTTGCCGGTGCCGCCGAGGGTCACCGAATGCAGCATCGATACATTGTCACCAACCACAGCGGTTTCACCGATAACAATGGAATGGGCGTGATCGATCATGATGCCGCGGCCGATTTTGGCCGCCGGATGGATATCGACGCCAAAGATCTCGGAAATTCGCATCTGGAAGAAATAGGACAGGTCGTAATCACCCTTCTGCCACAGCCAATGGGCGACCCGGTAGGCCTGCACCGCCTGATAGCCCTTGAAGTAGAGGATCGGCTGCAACAGACGATGGCAGGCCGGATCACGCTCATAGACCGCCATCAGATCGGCGCGTCCAGCGGCAATCAGATCCGGGTTTTCCCCATAGGCCTTGTCGACGATTTCGCGCAGGATCACCATCGACATCTCATTAGAGCAGAGCTTGGCCGCAATGCGATAGGACAGCGCCTTCTCAAGCGAGGTGTGATGCAGGATGCAGGCATGGATCAGCCCGCCCATCAGCGGCTGGCGGCTCACGGCGTCCTGCGCCTCGGTGGTGATCTGATCCCAAACCGGATCAACGGAACTAACGGCGTGGCGCGTCTCAAGCATGGCTCTGCCTCCTGTGTTGCGACCAGATTACCTATGTAAGCGCAAAAAGGCCAACCGCAAATCCGTGATGATAGCCATCGGATCTGCTGATCTTTCGTCTAGGTTCAGCAGATATGGTCGGGCAGCCCGTTGATTTTAAGGCCATCCACGCGCAAGATCAGGCCACACGCGTATCCGCACAGCCTCTGTGCGGCACGCAATGTGATCGCGCTGACGGCCTGCGCCAGCGCGCTACCCCCTTCGACCCTCACAGCCGCGACACCCGGTGGCGTCAGCGCAGCGTGGCACCGGATCACTCCGGATTATGCCTGACATGACGCGCCAATTGGGCCAGCACCAGCCGGGTACAGGACAGATATTGCGGCGCATCGTAAAACGGCTCATCCGCCAGCGTGAATTTCCGCGCCGCAGCACTCAGGGAGCCATCCCCCCAGTCCGGACAGAGCCGCCGATGGCGGCGCGAATGGCGCAACGCCTGCCCGGCCCCGGCAAAGATCCGCTCGCACAGCACGCGCCGCTGCGCTGGGGCCACCGCCAGCAACGCGCGGGCAGTGCTGGTGATGTCGCCGGGCAGGACAGGACGCCGCATCCCCGTCCCGCCTCAGACCAGCCGCAGGACGGTGGCCGCGCCCGCCCCGTAGCGGGCCGAGATCTGCGCCACCTCGACGCGATCGCCCGGTGCCACCGCATCCGCTGTCTGGGCCGCCACCGGATAGCTCCAGCCGGGACTGTCCAGCAGCTCCTCGCGCAGCACGTCACTGCCCCGCAGGATGCGCAGGCGGTAGCGCTCCAGATCCTCGCCAAGCGGGATCTCCGCCAGATCCCAGCGGTCGCCGTCGGTGCGGCTGCGGCGGATCCAGTCCAGCCCGACCGCACCGCTGCCCAACACGCCTTTCTGGCGCAGATGCACCGGCGCATAGGGGCGCAGACCTTCACCGGCAAAGGCCGCCTCCAGATGCACATAGCTTGGATCGTCATAGGGGCGCCGGGCGGTGCCGATGCGGTAGTGACGGCTAAGGCCGCGCTGATTGGCAGCCAGAGTGATCTGCTGCGGGGTGCCATCCAGCGCCACCACATAAGACCCCTTGGGCCAGGCCACCGGCATCCGCGCATCGCTGCCCTGCTGCCCACGCAGCCGGTCGCGCAGCAGATAGCGGCCCGGCGCGATCAGCTCGGCCTTGGCAAATTGCAGCAGCTCCCAATTGCCGGGGCTGCCATCGCCAATCGCCACCAGATTAGCCCCGTTCAGCACCGCTGTCCGGTCCCGGCTCTGGAATTGACCGGTGATCATATCGACTTCCAAATCTGCACCGCGCTCCCAGCGGCCCAGCGCGCCCGCAGGCAGCACCGTGTTGGTGATCGCAATGGTTGAGGCCGCGGCCACAACCTCTTCCAGCACATAATCCGCATCACTCTGCGCGCCATACAGGGCAACGCTCCCCGGCCAGGGCTGCGCCGTGACCGCCAGATGCGGCGCATGGGGCACCTCATCGCCGCCAATCAGCGGCAGATCCATGAACAGTGGCAGCACCGGCACTGGCGCCGCAAAGGCGGTGACACCGGGCAATTCCTCCGGCACCGGTGCGGGGTGGTAGTTCTCCGGCTCAATCCGAACCGCCTCGATCAGCTGCGCCGCACCCTGTTCGACCCGGTCGATCCGGTACCGGGCCTGCGCACCGCTGCCAACCTCCGGACCTGCCTCTGCCCCCGCAAGCGGCAGGCGGATCACATCGCCCGCGCCCAGCGCCATGGCGGAGGGCGGCAATTCCAGCCGCAGGGTATCGCGGGCCATCCGCGCTTCGCTCAGCCAGCGCTCCACCACCTGCCGCCCCTCGGCGCGGGTCAGCGCCATCGGCAGCTCATTGTCGCTGACCGCGTGGGTGGCCTCATCAGGCAGCACCGCCTCCTCACCGCGCAGATCATGGCGCCCGCCCCATTCGACAAAGCGCAGCCGCATCCGTCCGGCCAGCTCGGCCTCCGGCGCGCGGGTCTGTTCCAGCACCCCGTCCAGCTCCTGCCCCTCAACCAGCTGCGCCAGATCCAGCGCTGCGTCCTGTCGCCCATTGCGCAGGCGGAACCGCAGCAGCCCGTCGCGTTCGATGGCATCCACCCCGTGGCGCAGCAACAGTGGCTGCAGCGTGGCGCGCGCTTCACCAACGTCGCTGATCGCATAGCCGCGCACCAGCGCAGGCAGGTCGCTGACATCAATCGCCGCAATACCCGAGGCGGCACAGATCTCCTCCAGCACCGAGGCCAGCGTGCGCTGCCCCACCCGTCCGTTCAGCCAATGGCCGCGCAGGTAATTCTCCCCGTCGCTCCAGACCTCCACCGCATTGGGAAAGGTCGGAAACGGCCGCGCGTCCCAGGCCCAGACATAGGCGTTCGACATATCCAGCATCGGGCCGTCATAGACCTCGGAGACGGGGTTCATCCCCTCCTCCTCCCAATAGCCCAAAAGAGCACGCAGATAGGCCAGCTGCATCATGTCATCGCGCTGCCCGTCAGAGAATTTCGGCAGTTTGGATTCGGAGCTTTTGGGATCCAGAAACTTGTTCGGCTGGTTGGTGCCCTTGTCGATGGCGGCACAGCCCAGTTCGGTGAACCAGATCGGTTTGCTCTGCGGCTCCCATGCGGTGGGCAGCGCGGCACGTTGCCCGTTGATCCGGTCATGATGCGGCTTGGACCACCAGCTGCGCAGATCCTTGTAGCGCCAGATCCACGGCTCATCATAGGCGCCATCGGTGATCGGGGTGCGGATCTGGGCCGCCTCGGCCTCGGGCGAGTGGTAATACCAGTCATAGCCCTCGCCGCCCTCGATATTGGCGCGCAGATAGGTCTGGTCATAAATATTGGGCGCGCCCGCTTTGGCGTCGAGATGCTCTTCCCCCTCGCGCCAGTCGGACAGCGGCATGTAATTGTCGATGCCGATGAAATCGATCTGCTCATCTGCCCAGAGCGGATCGAGGTGGAAATAGCGGTTCCCCTCCGGGCTCTGGTAGCCCCAGTATTCCGACCAGTCGGCGGCATAGCCGATCTGGGTGTCCGGACCAAGGATCTGACGCACCTCCTGTGTCAGCGCCCGCAGCTCCGCCACCGCAGGAAAGCCTGCCTCATCGCGGATCTGGGTCAGCCCACGCATCTCCGAGCTGATGCAGAACGCCTCAACCCCGCCCGCCGCCGCACAAAGCGCGGCATTATGCAGGATAAACCGCCGCAGCCCCCAGTCCTCCAACGGGCCGCTATAGGTGACGGCGCCGTCAGCCACGGTGAAATCCGCCGCCGTTGCCGTGCCAAAGAACTGCTGCACCTCCATACGCGCCGTAGCCGTGCCATCGGGGCTGCCGGGCTGGCCCGGTGCCCGTGACAGGGTGATCCGTCCACGCCAGGGCAGATGCGCCTGTCCCGGCTCACCGCTCCAGGGATCGGGCAGATCATTGCCCGCCATCTGATCCATCAGGATAAACGGGTAGAACATCACCCGCTTGCCCTGCGCCTGCATTGCGCGAATGGCCTCGATCACCGAGGTATCGGTCGGGGTGCCGCCGTATATGGGTCTGTCATCCTGCCGCGCGATCAGCTCTGCCTCTGTCCGGGTCAGCCCGGCCACTGACCAGGGCATATTCGCCCCCTCGATATGCTGCCGCTCCACCTTCGGTTTGACGGTACAGGCCCGACAGCGCAGATCATTGCCGAACCACGACACAATCAGCGAGGCCGCGCCACAGGCGGGCAGCTCCTCGCCAAGGGTCGTCAGCGAGGTGACCAGATCGGTCTCTCCCGAGGGGCTGTGCGAATTGGCGGGCTTGGCCTGTCCCGGCCCGTGGTCGTAATGCACCGGCGTGCTGGCCAGCGCGTATTCCCCGGTCCCCGGCATCAGGGCAACCCCCTGCACCAGCTGCGGCAGATCCAGATCATAGGTGCTGGAGGCCGGTTGTTCGGCACGCAGCACCTCAAACGAGAATTGCGGCACCCGGTTGCCAAAACGGTCCAGCGCCAGGTTCTCCATCACCACATAGGCGGTGCCACGATAGGCGGGCACCTCGCCCGCACCCTCCACCGCCTCAATCACCGGATCGGGCAGCTGGTCCATGGTGCCGCGATAGACGGTCATGTTCAGATCCTTAGGCGCGACCTCCTCCCCATCAGCCCAGACCCGCCCGATGGAGGCGACCTCTCCGGCGCAGACCGCCACCGCCAGCGAGACATCATAGCTGTAGCTGGTGACCTTGGGCTGGCGCGGACCGCCGCCCTTGCCACCCCCGCCACTGGTGGTGGAGGTCTCGCGGAACTCGGACGCCCAGATCACCTGCCCGCCCACCCGCATCCGGCCATAGACCTGCGCAATCGGCTGGCCATCGCTGGCATGGGTCAGGCGGAACCGTTCCACCCGGCCGGTCTCCACCGGCTCACTGCCAGCCCCCAGCAGGCGGCTGTCGATGGCGCGTCCGACGGTGGCGCCAAGTGCGCGGCCAATCGCTACCGAGGACAGACCCGCCACAGCCCCCCCAACCGAGCCGCCAAGGGCCGCCCCCGCCGCAGAAAGAAGAATGGTCGCCATCACGTCACCTCATCAGCATCAACATCAGGAAAGGAAAACCGCGCCACGATCCTTCGTTGCCACGGCTGGCTCAGCGCGCTCTCGACCACACCGTGGCCGCAATAGGCATGGATGAACCGCGGGACCGGTTCGATCTCGGATTGCAGCGCGATATGTTTGGCCACCGCCCCCCGGCGCATCCGAAACAGGAGGACGTCTCCGGCGCGCGCCTCCTGCAGCGGTCGGGGGCTGAGATGGCGCAGAGCCGCCTGCCACAGCGCCTCCTCGCCCTGCGGTTCGGACCAGTCCATCGTATAGCCCGGCACCGCCTCCGGCTCCTGCCCGTAGACCTCGCGCCAGAGACCCCGGATCAGGCCGAGGCAATCGCAGCCCGCCCCGCGCCGGGCGGCCTGATGCACATAGGGCGTGCCCAGCCACCCCCGCGCCGCTGTAACCAGCTGGGCGCGCAATATCCCTCTCGCGCCGCTCATCTGCGGCTGCCGCCGGTGTTATTGCCGCTCTGGCGCGGTACACTCATCACCCAATCTTCGCCGGGGATATCGGGAAAGCCCTGAAAATTGACGCCATTGTTGAACTTCAACCGGCAGGTCTTCAGCCGCTTGTCGCAGCCCGCTGCCAGATGCAGCAGATCGCCGGGTCGGATCTGCGCCCGCAACGGCTCCCACAGGGTCAGCTGGCGGTGCTCTGTGTTCGGATCCGGGGCGCTTGCGTCCTGTCCCAACCGTCCGACCTGCTGACGGTCCTGCTTGATCCAGCCCCACAGCCCCACTGCTGCGCCGCTCATCACCGTGAGACGACCCGACGTGAACCAGTTCGGCTCAAACCCCGGCAGGGCGGCAAATCCGAAATACTGCCCCTCGCGGATTTCTTCGGCGGCCAGCTCCATCGTGTAGCCCGGCGTTGTCATGTCAAAGCGGCAGGCGCCATCGCCCAGCACCGCCGTGCAGGGTTTCTGGTAGATCCGCCCCATCGGCTGATTGAGCGCCTCCGTCAGGCCGCGCAACTCCGCCTCAAAGGCACCACCGGCACGACGGATCTGGCCAAAGCTGCCGCGAAACTGCAACCAGCGCACCGAGACATCGGCCCAGTTCACCAGCCAGCAGCGCACCTCAGCGCCGTCAAAGCGCCCGGCTTCGATCTCGCCCTCACGGATGGCGACATCGCTCAGTGCGCCAAGCGCCTCGGTGTTGTCGACCGCCAGCCCGGTGGCCTGTTGCAGGCTGCGCGCCGTCAGGCCCGTGCCTGCGCGAAACAGCAGACCTGCCTCGCCCTCGGCAGCGCTTTCGAACCGCAGGTCGCGGTCATGGTCGGTAAAACCGAACCGCACGCCATCGCTGCGGGTCACCAGCCAGCAACGACACAGCGTGGTCAGACCGCTGGCCACATGGGATTGAAACGCCTCGCTTACCCCCGCCATCAGACCCGCACCTCTACCACTGGGACATTGGGCACGTCGCCCGCCTGAAAGGACGCCACGCTGGTCTGGATCCGGTCGGTGTCAAAGCGCACCGGGACATCGAACTCAAACCCCGCCTTCACCGACAGGCCCGCCTCTGGCGGATGCGCCAGCGTGATGGCCCCAAGGGTGCTGTCGAGCGTGTAGTCTACCGTCTCCTGCAAGGCGTCCTGCTCAATCCCGATGCGCACGCTGCCCGCCACCGGTTTCGTTATCGGACGCTGATAGGCAAAGCTGCCGGAACGATAGGTCTTGCTCAGCTGGAACACCCGCTGCGCCCCGTCGCCCATGCCGATCACCTGATCCCCAAAGGTCACGTCCTGCGTCGCGCGGGCGGATTTGTAGTCGGACCAATCTTTCCAGCGAAAGCCGTACATCTGGCCTTGCCGCGCCTCGAAAAAGGCAATCAGCGCCTCGATATCCTCAAGGCCCCGCAGACCCAGCCCCGCGTCATAGCGGCGACGGGAATGCGCCCAGGGGGTGTTGCGTTCCTCATGCCCGTTGGCAAGCGTCACCACATCGGTGCGCCGCTCGGGTCCGCCGATCGAGCCGAAGCTCAGCGATGCGGGAAATCTGACCTCGTGAAAATTCATCTGCTGTCCTCCGGCTCAGCGATTGCGATTGCCACGCGACAGGGCGCGGCTCAGCTGGGCCGCGATCTGGCCCTGACTGCGTTGGAACCCCTGCACATCGGGGGTCTGGATGTTCATCACGACTGAGGTCGCCCCGCCCCCCTGACTGCGCACACCAAGCGCCCCATCGGCGCCACGGGTCAGCGGCAGGATTGCCTCTGGGCCTGCCTCGCCCATCAGTCCGGTGCCGCCGCGCATGGGAAAGCTCACCGGGCCGCTGACGATCCCCCCCTTGGCAAAGGGCATCACCCGGCCTTGTGAAAACGCTGCCCCATCGGCAAAGGGGAGAATGCCGCTCATCAGTTTGCCCACCCCATCCGACAGCAACCCACCCACATGGCTGGTCACGGGTTTGATGGCCGCCGAATAGGTGGTCTGGATCATCGACTGCGCCATGGTATCCAGCGCATCCGAGAGCTTCATGCCGTCAAAGACAACACCGTCAAAAGCGCGGCGCAGCCCTTTGGACATACCGCGTTCCAGGGTCTCGGCATCCTTGCCGGTGGCGGCAAAGGCGGCGCGCACCCGGCGCAGTTCGGCGTCGAATGTGGCGGCCATACCCGCCGCATCGCCAAGGCTGTCGCTCAGCGCCTCGCCCTGTTGTTCCAGCTGGTTCAGTCCTGTGTCACTCATCGCTCACTGCTCCTGTTTTCTGGGGATTTCGGCGCGGCGGGATCCGGGAAGGCGTGCATCAGCTGATCCAGACCTGCCCGCCCCAGAGGGACGGCGCCAGTGTCCTGCCCCAGCATCAGCCGCAGCTCTGCCGGGGTGAGCTGCCAGAACTGGTCCGGCGTGAGGCGCAGCCCCACCAGCCCCGCCCGTATCAGCGTCGGCCAGTCAAGGCCGGTGCTCTGCCCATCTGTGGTGCGCTGCTGGGGCGTCATGGGGCCACCCATCCCGGCCCCTGTCCCGGAACCTGTGCGCCCGCCTCTCCCGGCAGCGCGAAGCTGCGCGCCAAGAGCTGTGCGGCGGTCCGTGCGGCCTGCATCGGACCGCCATCGATATCAGCAGCAGCCAGATCGGCCTCACTCAGCCGGTGACCACCGCCCTGCAGCCCTGCAGCCAGCAGCGCCAGCACATCCGCCGCCGAGAATCCGCCGCTTTCGAACCGGGTCACCAGATCAATCAGTGATCCTGTCCTGAGCCGCGTTTCCAGCGTCGCCAGCGCCCCGAGAGTGAGTTTCAGCGCCAGTGTCTCGCCATTGATCCGCAGGGCCACCTCGCCCGCATAGGGATTGGCTGCATAGGCGTTAACGGCTGGGGCTGACTGTTGCGAGGAGGTCATGATCGGTCCCCCCTTAGATGGCGGTGAAGACCAGCGCCCCGGCGCTGGCCAGCGACAGCTCATAGGTCGCCTCGCCATTGTGGCTGCCGGCATATTCCAGCGCGGTCACCTGAAATGCGCCTTCGACAATACCGAAATCGGGGATGATCACCTGAAACGCCGGGGTCAGCCCGTCAAAGAACAGCTGCCGCGCCCGCTCATCCGTCCCGGCATCGCGAAAGATTCCAGAGCCAGAGATATTGGCCGAACGCACCCCCGCGCCGGACAGCAGCTCACGCCAGCCGCCCTGGCTTTCCAGACTGGTGACATCGACACTTTCGGCGTTGAAGCTGATCCGCGTGGCGCGCAGCCCTGCGATGGTTTCGAACTGTCCGTCGCCGGTCATATCGACCTTGACCAATAGATCCTTGCCATTTTGGACACTCATCGTGGTGATCTCCTGTGGTTGAAGGGGGCGGCACGGCATGAAAGACATGAGCTGAACCGCGTAATTATCTGAATTATATAAGCTGTTATGGATTGACTGCGGTCAGACATCCTCCAGCCGCGCGGCAAAGCGCAGGCGGATCTGACGGCCACCGGAAGAGTTGCGGCTGGCGCTGGCGCGTTCAAACCACAGGCCCACCAGCCGCCCGCGTGACAGGGTCAGCGAGGCGCTGGCGAGGCTGTCACAGAGCATGGCGGCAATCGCCTTTGCCCCGGCGAACCCGGCAGTATCGGTATGCACGGTGATCTCCACCCGGTGATGGGCACCGGCGCCACTGCGATCAGAGCGGTCGCGCACCTCCTCGGGGCCAAGAGTCACATAGGTCTGCGGCAGCGTGCCTGCAGGCAGCGCGTCATAGATGGCGCCGCTCAGCGCGGTGGTCAGATCGGGGTCCGCGCTGAGGTGCTGAAACAGGGATTCCTGCAATGGCAGGGCTAGGGCATAGGTCATGCGGTGGTCTCCTCGGTGGCGAAACAGGTCAGGTAGCGGCCGTCGGGGTCGCCCTCGGCCACCGCATCAATGCGAAAGATCCGGGCACCATCGCGCAGCCGCTGGTCCGGCCGGGGCCGCGCAGGGCTGCCGGTGGGATGGGCACGTAGAGTGATGCGGTAGCGTTGCAGCGACAGGCTGGTGCCGGATTGGTCGGTGCTGCGGCCACTGAGGGCACGCAGCTCGCACCAATGGTGGCCAAGCAGCTGCCATGCCTCAAGAAACCCGCCCGCGCCATCCGAGGTGCGGCGCGGATCTTCCAGCGCCAGACAACGGTTGAGACGTGGTGTCGTGGCGGATGCACGGCGGGAGGTGGTGCGGCGGCTCATGCGCCTGCCCCCGGTCCGAAGTTGCGACCAAACCCACGGTCCCCAGCGGCCCCCACCCCCAGGCTCACCCGCAGGGCGCGGTAGCGTTCAATCAGGCTGGTGACGCCAAAGGGCATACAACCGCCCTGCAGCCGGGTGTCATCGCGGAATTCATAGTAATGCGCCGCCAGCATCAGCACCGCCTGCGCCAGATCACCGGGCAACGCCGCCCAGCTGTTGGCCATGCCCGCGCGGATCGCGATCCGCACCGCACCACCGCTGGCAACCATCGGCAGCGGTCCCCCCACCGGGCGCAGCCGGGGCTGCTGGCTGTCGGGTTCCAGCCGGTAGCGCTGCGAGGCCAGCAGCTGTTCATTGCCTGATCCATCCACCAGTGTTACCGATTGAATCATCTGCACCGGCGCCAGCGGCAGCGCCTGCACCTGCGGGTCGCGCCAGGTCGAAAGGGTCAGCAGAAAATCCCGCGCCAGCAACACCTTGCCGGTGCGCGCCTCAATCGCCGCGATGGCCGCGCGCAGGAAGCTGATCAACACCGCCTCCTGCAACCCCGCCTCGTCAAACCCGGTGCCCAGACGCAGATGCGCCTTGAACGCCTCTTGCGGCAGGACTGCCTCTGGCACCGGTGTCACTTCATTCAACATCATCTCTTCACTCCAACGGCTGTTCGTTCGGGGGCTGCTCGGGCTGGCTGTTGCCGGATGGGTTGGGGCGGATGCGCGCCGGGCTGCTGCCGCGGGACGGAAGGGGAGCAGCTGGACGACAGTGGCCGGGGCGCGCATCCGCAGACGGCACCGGCGAGCCGACACCGCCATCGGTCCAAGCGTCAGCTCAGGCCGAATTTCAGCAGCTTGATGGCCGCAAAATCGCTGACGTCACCGCCCACACGTTTGGTGGCATAGAACAGCACATGGGGTTTGGCGCTGAAGGGATCGCGCAGCACCCGCAGATCCGGGCGTTCGGCGATGGTGTAGCCAGCCGCGAAATCGCCAAAGGCCACCGCATAGCCGTTCACATCGGCGTCGGGCATATCCTCAGCAATGACAACGGGATAGCCCATCAACCGCGCCGGTTCTGCGGCAGCCAGACCATCGGACCACAGGAAGCGGCCATCGGCGTCCTTCAACTTGCGCAGCAGACCGGCGGTTTTGGAGTTCATCACAAAGCTGGCGTTCGCCCGGTACTGCGCGCCAAGCGCATAGACCAGATCAATGATCGCATCCCCATCGCCGATATCGCCCTCAACACCGGTGGTGACATAGCCAATGTTGCCCCAGCTCCAGCTGTCATTGGCCACCACCGGGTGGTAGAGGATGCCGGTCGGCTTGTCATTGCCATCCCCCATGATGAAGGCGGCGGCCTCTGCACGGGAGAATTTATCCGCGATGCGCCCCGCCAGCCAGCCCTCGATATCGAAGGCGCTGTCATCCAGCAGCCGCTGCGACGCCTTGGGCAGCGCGCTCAGCTCATGCAGCGGGATGGTGATCCGGTCGATCACCGGGGTGGATGTCTCGGTCACGGCGCCGGTTTCATTGGCCCAGCCATGGCCCACATCTCCATGGTCGATCAGCACGTCATAAGATGTCGCCTCTACCATCACCACCGACGCCACTGCGCGGATGGAGGCGGTGCTGGAGAGTACCGATTTCACGCTCTCGGCGGTTTGCGGGTCAACCAGATAGCCACCATCGCCATTGACGGTGGTGTTCATCGCCTTGGCATCCAGATCAAGACCACGCAGGGCAGCATCATCACCGGAACGGAGATAGGCATCCAACGCCTTTTGATGGGGGGCCGTGCCCGCATCAGCTGCGGCCAGAGGGGGACGATTGGCAAAGTGGGATTTGCGATCCAGCATGGTCATACGCTCTTCTGTCTGTTTCAGTTTCAGGGCAATGTCGTCTTTGAACCCGTTGAAATTATGCACGAAGTCGGCAACGGCCTGCTTGACCTCCTGCGGGGCCACATGGGAGTGGGCCGTTGGGTCCGGATGGGATTGGGTGTGGCTCATCTGTCTGTCCTTTGGGTCGGTTGGAGAAGACGGGAAACGGTGATGTGCTCAGCCGAGGGGGGCGAGACTGGCCCCGCTGCGCAACATCTCGATCACCTCGCGCCAGATCTGCGGTGTTTCGCCCGGATCGCTCAGATCCGGCTCAGCGGATGTCGATTTGGCGGCAGTCACGGGCTGTGCCGTGGGGGTGACACGGGCGGCGGGCAACATCGGGAAGGTCACCAGCGACACCTCCCAGAGATCCAGTTCCGCGAGGCAGCGACCGCCGCCTTTGCGCGCGGTGGCGCGGCGGGTGCGATAGCCGATGGAAAGACCATCCAGCGCCCCCACCGCGATCAGCGCCGCAGCCTCGGCGCCCTTTTGGGTGCGGGTCAGAATGCGGCCTTTGACATACAGGCCACGGGCATCTTCGCGCACGACGTCCCAGACACCGATGGGCTGGGCCGGATCATGCTGCCAGAGCATTTTCACCGCGATACCCGCCTTTGAGAGGCGGTCGAGGGACGCCTGATAGGCGTGGGGTTGCACCAGATCACCGCCGCCATCGACGCAGCCGAACAGGCTGGCGTAGCCGCTGATCACGACCATATCGTTGGCCTCAGCCCCGATGGTCAGATCCTCGCCGAAGCGGGCGAATTTATGTTCCAGATGCTCATCATGTCGCAT

Protein sequences of DBSCAN-SWA_1

>NC_018286|1908155:1942975|1922673_1923864_+|WP_014874850.1|DBSCAN-SWA
MGWNALDTMDLAGKRVLVRVDINVPVEDGRVTDDTRIQRVAPTIKDILAAGGTPILLAHFGRPKGKVVAEMSLRPLVPALEAAFGAPVTFAADCRGPAAEAAVQGLPAGGVLLLENTRFHAGEEKNDADLAAEMAKLGDIYCNDAFSAAHRAHASTEALARLLPACAGRLMQAELTALEAALGQPQRPVTAVVGGAKVSTKLELLGNLVGKVDNLVIGGGMANTFLAAQGIDVGKSLCEHDMADTAREILSKAETQGCKIILPIDVVVAREFKAGADNETVAADACPADAMILDAGPQTVAAVADTLFASKTLIWNGPMGAFEIAPFDAATNAAAQQAASLTKSGALVSVAGGGDTVAALNQAGAAADFTYISTAGGAFLEWMEGKTLPGVAALEG
>NC_018286|1908155:1942975|1939929_1940301_-|WP_014874867.1|head,tail|DBSCAN-SWA
MSRRTTSRRASATTPRLNRCLALEDPRRTSDGAGGFLEAWQLLGHHWCELRALSGRSTDQSGTSLSLQRYRITLRAHPTGSPARPRPDQRLRDGARIFRIDAVAEGDPDGRYLTCFATEETTA
>NC_018286|1908155:1942975|1913152_1913614_+|WP_014874841.1|DBSCAN-SWA
MLAPSDPAPSFNLPRDGGGTVTLEELRGKAVVLFFYPRDDTPGCTKESIGFSEHLQAFADAGAVVYGISKDPVAKHDKFVAKHSLTTPLLSDAEGTTCEDYGVWKEKNMYGKKHWGIERSTFLIDAEGNIAQIWRKVKVDGHVAEVLEAAKAL
>NC_018286|1908155:1942975|1920218_1921154_-|WP_162893394.1|DBSCAN-SWA
MLPWLAAARADPAIWSREWPTTDFSRTIVADWGEIKSGGPPKDGIPALSDPAFHPAAQVKGLSPAEPVVVLDLPGQAAHAYPLRYLIWHEIVNDRVGYTPVAITYCPLCNSAMSFDRRVAGRTLSFGVTGKLRQSDMVMYDRESESWWQQATGTGIVGEMTGRELRQLPSWLDSWQGFQAAYPKGLVMAEPRHNRSYGRNPYQGYDRSNWPFLYDGAPPPHGIAPLARVVRVGDRAWPLARLAKAGEIREAGVILSWRAGQASALDAGHVGKGRDVGSVRVQGRNGADLPHDVMFAFAYHAFWPKGDWMLE
>NC_018286|1908155:1942975|1928817_1929873_+|WP_168155301.1|DBSCAN-SWA
MLLYIFLGFLIGFVLSLRFIRNPRKALNWGVILGVVPLVLLLGPANAPMQGIGSVLNFAFFALGPIMLVPFVASSAPLGMAGASIVLWIGHQRPRWASWATGVAILGLTVSVTLLPVAQREIAKRHLAEDQDVRATEIIRADFTGTLAEHQVAFPASPRLRVFDGCAPDVQAGLFGCSTNLTNPVSGFTKPNDVLLHERRDPINFRTIRVSPVEHDCRLGNDYCLTQEKVDHWCRETRPDQADSIWCRDIPTMQFELRRDATPGPSDRDEPELTAQYSDTALGPGRVTCFYSPDPAETDRQGVTCRLVFELANRVSATLGVRREQITAGDPELIKTIELIPDYWASLTETR
>NC_018286|1908155:1942975|1941124_1942309_-|WP_014874869.1|capsid|DBSCAN-SWA
MSHTQSHPDPTAHSHVAPQEVKQAVADFVHNFNGFKDDIALKLKQTEERMTMLDRKSHFANRPPLAAADAGTAPHQKALDAYLRSGDDAALRGLDLDAKAMNTTVNGDGGYLVDPQTAESVKSVLSSTASIRAVASVVMVEATSYDVLIDHGDVGHGWANETGAVTETSTPVIDRITIPLHELSALPKASQRLLDDSAFDIEGWLAGRIADKFSRAEAAAFIMGDGNDKPTGILYHPVVANDSWSWGNIGYVTTGVEGDIGDGDAIIDLVYALGAQYRANASFVMNSKTAGLLRKLKDADGRFLWSDGLAAAEPARLMGYPVVIAEDMPDADVNGYAVAFGDFAAGYTIAERPDLRVLRDPFSAKPHVLFYATKRVGGDVSDFAAIKLLKFGLS
>NC_018286|1908155:1942975|1918634_1920131_+|WP_014874846.1|DBSCAN-SWA
MAELLVTAASNVAPPFDFSDFDFTKVAVLSATDTQIAVQYGAFVMVFQGSFSFDESGNLSPDSPLNGFGLFYDQSLIMSVSGFTLPSQMIADGDLYALLAVALSGDDIITSAWNGGERINAFAGNDTIRAGNGDDTIFGGAGQDELVLGDGVHTYSFAFDDSAGALLTTTKGRDMLFDVETVRLANQTLHIQEGSATDEALHSTNVDDTTRSDMIHGRGGDDTITGGAGKDFLLGGAGEDRLSGGKNDDFLDGGLDDDHLSGNAGDDNLRGSLGNDTLIGGAGNDTLRGDNDVGPDDNADDLLIGGSGHDSLDGNAGNDTLKAGNGADTLHGGEGDDILNGGRGRDLITGDDGRDTLAGGRANDTLTGGAGNDRLSGGAGHDVMRGDAGNDLLIGGRGHDTLFGSDGADRLIGQSGHDRLTGGSGGDSFVFARGSGRDTITDFQLGEDLIQITRGADRIDHLGFAQLGADVRITFANVSILVEDVTVDQLMNTDNFLF
>NC_018286|1908155:1942975|1908155_1909226_-|WP_014874839.1|tRNA|DBSCAN-SWA
MKLSDFDFDLPDDRIATRPAVPRSSARLLVAEGDRIRDARVANLGQWLRSGDRLVLNDTKVIPARLSGLRHRDTAQGPMAAKVEVTLLDPGADGSWAALLKPLKKVKPGEEIVFSDALSATLERVEDGQGHLKFNLSGTDFDAALAEAGAMPLPPYIAAKRPADEQDKTDYQTVWARNSGAVAAPTASLHFDDALLAELQAKGVEISYVTLHVGAGTFLPVKVEDVTTHRMHAEWGRVSAEAATEIAATKAAGGRVIPVGTTALRLIESAGQSGAIQPWEGDTDIFIYPGFTFHVADALMTNFHLPKSTLLMLVSALMGQDRIRAIYDHALAEEYRFFSYGDASLLIPPTAEMSQT
>NC_018286|1908155:1942975|1915042_1916374_+|WP_014874843.1|DBSCAN-SWA
MRTRLAIKIHAFLERRFPERRVFLKSDSDTRFIRLRSETQLIAFAGMALLVAWSIVATAIVLMDSIGSGNFREQAKRDQMTYRARLNALSGERDDRAAEALAAQERFNAALTQISSMQSELLASETRRRELETGIEVIQTTLRQTMKERETARDALVALKQETAADSPAQMMAVSAPVQMEFMADALAETAAQRDQIEANAQSALEQRDALELELRLLDERNDQIFRQLEEAMEVSVAPLDKMFRSAGMPTDRILEQVRRGYSGQGGPLSPLALSTRGEEPTREELRANNLLHQMNQLNLYRLAAQKAPFASPVNLNLVRRSSGFGYRRDPKTGGRRLHKGSDFAGRTGTDIFATADGVVTHAGWQSGYGKLVTIQHAFGIETKYAHNSNIRVKVGQRVSRGDHISDMGNTGRSTGTHLHYEVRVNGNPVNPMIYIKAARNVF
>NC_018286|1908155:1942975|1939009_1939423_-|WP_014874865.1|tail|DBSCAN-SWA
MSVQNGKDLLVKVDMTGDGQFETIAGLRATRISFNAESVDVTSLESQGGWRELLSGAGVRSANISGSGIFRDAGTDERARQLFFDGLTPAFQVIIPDFGIVEGAFQVTALEYAGSHNGEATYELSLASAGALVFTAI
>NC_018286|1908155:1942975|1935622_1936093_-|WP_014874859.1|DBSCAN-SWA
MSGARGILRAQLVTAARGWLGTPYVHQAARRGAGCDCLGLIRGLWREVYGQEPEAVPGYTMDWSEPQGEEALWQAALRHLSPRPLQEARAGDVLLFRMRRGAVAKHIALQSEIEPVPRFIHAYCGHGVVESALSQPWQRRIVARFSFPDVDADEVT
>NC_018286|1908155:1942975|1938340_1938595_-|WP_014874863.1|tail|DBSCAN-SWA
MTPQQRTTDGQSTGLDWPTLIRAGLVGLRLTPDQFWQLTPAELRLMLGQDTGAVPLGRAGLDQLMHAFPDPAAPKSPENRSSER
>NC_018286|1908155:1942975|1925753_1927139_+|WP_014874853.1|DBSCAN-SWA
MATEILMPALSPTMEEGTLAKWLVKEGDTVNSGDILAEIETDKATMEFEAVDEGVIGKILIGEGSENVKVNSPIAVLLEEGESYDPDAAPAASAPSASEAPAAEAPAAPATTAAAAAAPAAPEVDTTPDWPEGTEVVQTTVREALRDAMAEEMRRDDDVFLMGEEVAEYQGAYKISQGLLDEFGAKRVIDTPITEHGFAGIATGAAFGGLRPIVEFMTFNFAMQAIDHIINSAAKTLYMSGGQMGAPMVFRGPNGAAARVGAQHSQDYAAWYMQIPGLKVAMPYSASDAKGLMKTAIRDNNPVIFLENEILYGKSFEVPKLDDYTVPFGKARIWREGTDVTIVSFGIGMTYALEAAEKLAEDGISAEVIDLRTLRPMDTGSIIKSVMKTNRLVTVEEGWPQGSVGSYISSVVMQEAFDYLDAPVITCTGKDVPMPYAANLEKHALVTTDEVIEAVKQVTYR
>NC_018286|1908155:1942975|1931357_1931654_-|WP_014874857.1|DBSCAN-SWA
MRRPVLPGDITSTARALLAVAPAQRRVLCERIFAGAGQALRHSRRHRRLCPDWGDGSLSAAARKFTLADEPFYDAPQYLSCTRLVLAQLARHVRHNPE
>NC_018286|1908155:1942975|1924121_1924421_+|WP_014880143.1|DBSCAN-SWA
MTRSNRPSLGAFVFSTIAFALSAYFTFAAVQGDFGLFRRVEIQAEAEALRQDLDQLKRETAQMENLTHRLSDDYLDLDLLDEQARSVLGLLRADEIVIR
>NC_018286|1908155:1942975|1930249_1931065_-|WP_014874856.1|DBSCAN-SWA
MLETRHAVSSVDPVWDQITTEAQDAVSRQPLMGGLIHACILHHTSLEKALSYRIAAKLCSNEMSMVILREIVDKAYGENPDLIAAGRADLMAVYERDPACHRLLQPILYFKGYQAVQAYRVAHWLWQKGDYDLSYFFQMRISEIFGVDIHPAAKIGRGIMIDHAHSIVIGETAVVGDNVSMLHSVTLGGTGKEEEDRHPKIGDGVLIGAGAKVLGNIKVGHCSRIAAGSVVLQEIPPCKTVAGVPAKIVGEAGCDQPSVSMNQVLGGGKPQ
>NC_018286|1908155:1942975|1927151_1928486_+|WP_014874854.1|DBSCAN-SWA
MPTEILMPALSPTMEEGTLAKWLVKEGDTVASGDLLAEIETDKATMEFEAVDEGVIGKILIPEGSEGVKVNSPIAVLLEEGESADDIGTTPSAPAAAADEAAPVAPEEAAPASFPAPAEAPAAATPAPAAPQGADGNRIFASPLARRIAADKGLDLAQLNGSGPRGRIVKADVENAKPQVAAAPAAAAPATAAAPAAAVSTGPSTDQVARMYEGRTYEEVKLDGMRKTIAARLTEAKQTVPHFYLRRDIQLDALLKFRGELNKQLEARGVKLSVNDFIIKACALALQAVPDANAVWAGDRVLKMEASDVAVAVAIEGGLFTPVLQNSDTKSLSTLSTEMKDLAKRARDRKLAPHEYQGGSFAISNLGMFGIDNFDAIVNPPHAGILAVGAGVKKPVVGADGELAVATVMSVTMSVDHRVIDGALGAELLNAIKDNLENPMMMLA
>NC_018286|1908155:1942975|1940297_1940942_-|WP_044040925.1|DBSCAN-SWA
MLNEVTPVPEAVLPQEAFKAHLRLGTGFDEAGLQEAVLISFLRAAIAAIEARTGKVLLARDFLLTLSTWRDPQVQALPLAPVQMIQSVTLVDGSGNEQLLASQRYRLEPDSQQPRLRPVGGPLPMVASGGAVRIAIRAGMANSWAALPGDLAQAVLMLAAHYYEFRDDTRLQGGCMPFGVTSLIERYRALRVSLGVGAAGDRGFGRNFGPGAGA
>NC_018286|1908155:1942975|1916363_1916906_+|WP_014874844.1|DBSCAN-SWA
MFSKSKINEPGQKAAEATPAAPAPSSAPVPPASDFKATAPKAKPPASVLSSDLHITGNLKTTGDIQVEGTVEGDIRAHLLTIGESATIKGEVTADDVVINGRIVGRVRGLKVRLTSTARVEGDIIHKTIAIESGAHFEGSVQRQDDPLNPGKAAAPRAAAPAPAPSAAVTAATAAHKSEG
>NC_018286|1908155:1942975|1937687_1938344_-|WP_014874862.1|tail|DBSCAN-SWA
MSDTGLNQLEQQGEALSDSLGDAAGMAATFDAELRRVRAAFAATGKDAETLERGMSKGLRRAFDGVVFDGMKLSDALDTMAQSMIQTTYSAAIKPVTSHVGGLLSDGVGKLMSGILPFADGAAFSQGRVMPFAKGGIVSGPVSFPMRGGTGLMGEAGPEAILPLTRGADGALGVRSQGGGATSVVMNIQTPDVQGFQRSQGQIAAQLSRALSRGNRNR
>NC_018286|1908155:1942975|1937039_1937672_-|WP_014874861.1|DBSCAN-SWA
MNFHEVRFPASLSFGSIGGPERRTDVVTLANGHEERNTPWAHSRRRYDAGLGLRGLEDIEALIAFFEARQGQMYGFRWKDWSDYKSARATQDVTFGDQVIGMGDGAQRVFQLSKTYRSGSFAYQRPITKPVAGSVRIGIEQDALQETVDYTLDSTLGAITLAHPPEAGLSVKAGFEFDVPVRFDTDRIQTSVASFQAGDVPNVPVVEVRV
>NC_018286|1908155:1942975|1939525_1939933_-|WP_014874866.1|DBSCAN-SWA
MTYALALPLQESLFQHLSADPDLTTALSGAIYDALPAGTLPQTYVTLGPEEVRDRSDRSGAGAHHRVEITVHTDTAGFAGAKAIAAMLCDSLASASLTLSRGRLVGLWFERASASRNSSGGRQIRLRFAARLEDV
>NC_018286|1908155:1942975|1917148_1918393_+|WP_014874845.1|DBSCAN-SWA
MAIFTVNDPTGTLSLNNLGDLGFDNISLNSRSVNQLFFTSPTGTSITLTGDFSSSSPYFWTIESMAVNSGGTPVYAISEFSMNFYRFSASSGAALEAAILTGDDTITSNMAEGTRWLAYGGDDVISLGIGDDYVHGGYGTDRLIIHDTYGRADISSVYGGVWIDSADGRDTLLSIEQLQFSNRSFSLSVDTSSSTSMSGDRDNTLTSDIMLGGLGADTLAGLSGRDMLLGEEGNDHLMGGEGHDTLKGGDGHDILLGGSGRDWLAGDLGEDAISGGSHGDKLIGGGGHDTLRGQDGHDVLRGNSGWDQLLGGRGNDRIYGDGGQDRLIGQEGNDTLTGGAHADTFVFHRGYGTDIITDFTVGEDRIQIGRGADGTDDLTFTSQGNSVQITFADVTIMVENSTLAQIEDADNFLF
>NC_018286|1908155:1942975|1936089_1937040_-|WP_014874860.1|DBSCAN-SWA
MAGVSEAFQSHVASGLTTLCRCWLVTRSDGVRFGFTDHDRDLRFESAAEGEAGLLFRAGTGLTARSLQQATGLAVDNTEALGALSDVAIREGEIEAGRFDGAEVRCWLVNWADVSVRWLQFRGSFGQIRRAGGAFEAELRGLTEALNQPMGRIYQKPCTAVLGDGACRFDMTTPGYTMELAAEEIREGQYFGFAALPGFEPNWFTSGRLTVMSGAAVGLWGWIKQDRQQVGRLGQDASAPDPNTEHRQLTLWEPLRAQIRPGDLLHLAAGCDKRLKTCRLKFNNGVNFQGFPDIPGEDWVMSVPRQSGNNTGGSRR
>NC_018286|1908155:1942975|1921985_1922492_-|WP_014874849.1|DBSCAN-SWA
MAEIKDPENTIIMELKDGKVVIELLPDVAPQHSARMKELARSGAYDNVAFHRVIDGFMAQTGDVQHGDMEDGFNLRMAGTGGSDLPNVPAEFSKLPHDRGTLGAARSANPDSANSQFFINFKDNHFLNGQYTVYGRVIEGMEHVDAITRGEPPANPDRMVSVKVAADV
>NC_018286|1908155:1942975|1909329_1913052_-|WP_014874840.1|DBSCAN-SWA
MDSEQEPSSSASADAVQDAGPSGAVAAEGVAVAKAVPPPDGPGFLGPDEEAPEVTAAPEGEEAEAERIMQDEAVPVPVPGPRASDGISAGDLVKPADEDAETVAAAVSQPASDVRAKPKPRILRRMLRSAAITAVVLALLASGVVFLGLGTRLDAPDWVRDRVERRIERHLGGLSIEFGAIHLVVNRGWRPRISLRDVTLRDETGARVARLADAQASLAMRPLLRGQIRPKTIMLSGLYGTLRRDNSGGLALSLAEGEAPLRQAATLPALIEQWDRQLELPVLSALVEVETDALTLRYEDARLGRVWTLDGGSIRMNRSGQDIELAAGFSLLSGRDYVGTVEANYSSAIGDKAAEFGVLVNSVASKDIAAQSAALGWLDVLDAPISGSLRGAISSEGALLPVSASLQIGEGVIQPTAATRPVPITGAQSYFTYLPDRQELRFNELSVNSGWGSGTMEGRARLIGVENGQLTDLVGQLRFQGLSLNPAKLYDTPLDLAGVTADFKLEMAPFRLRLGEMLVRDGETRILLDGEISAGQTGWDYALNGRANRMTAERLKEVWPAAAPPKPREWVRENLLGGYARDVNFAMRGSGTAKPFVYLDLAFEDAAVKFQKSLPPLREAAGQFSLYGNRLVVMATKGWVTADQGGRVDAAGTSFIIPDTSVKDGAPGIARIEASGPVTAALSLLNRPPLSVMDKAGLPVDLASGQVALSGTLSLPLRKGVTPEEITYHYRGHIRDAASDVLVPGERLSAEVLGLSGDQGHVQIEGDGALSGVPGSLVWRQAVGPAVERASAAAGQAPPVRVKGTIELSQDTVDRFDIGLPAGSVFGRGVGRYEVVIDKGVAPKLTLESDLSGLGLRIPALSWRLSEATTGQLRMRATLGETPRVEALSLEGAGLQASGNVTLAPGGGLSRALFDRVELRNWFRGAVELVGRGTRAPGINIRSGVLDLRQMPDGSGGSGSSGGSSGGTGPITLQLDRMQVTDSIALTGFRGRFSTTGGLNGNFTAALNGQTGVNGVVVPKDGGFATRIQSQDAGGVFRAAGVLRHGSGGTFDMSLVPAPGAPGEYDGQIEVKNTRIKDAPSMAALLNAVSVVGLIDALAGQGILFTTVEAKFRLGATHLIVHESSAVGPSIGLSMDGNYDLERSVLNMRGVISPIYLLNAVGRVFTRKGEGLIGFAFTLKGAADDPRVQVNPLSGLAPGIFRELFRGPAPSLPGEEPPSTVVPRAERERPPYSVSPGEDR
>NC_018286|1908155:1942975|1924723_1925737_+|WP_014874852.1|DBSCAN-SWA
MAARKSVKKPNVSADELLEYYREMLLIRRFEEKAGQLYGMGLIGGFCHLYIGQEAVVVGLEAAAEDGDKRVTSYRDHGHMLACGMDPNGVMAELTGREGGYSKGKGGSMHMFSKEKHFYGGHGIVGAQVPLGAGLAFSDKYKGNDRVTFAYFGDGAANQGQVYETYNMAQLWDLPVVFVIENNQYAMGTSVQRSTKSPALWKRGEAYGIKGEEVDGMDVLAVKEAGERAVAHCRAGKGPYILEVKTYRYRGHSMSDPAKYRTREEVQKMREERDPIEQVRDMLLTGKHATEDDLKAIDKEIKDIVNKSADFSKESPEPALEELWTDIYADDLPQETA
>NC_018286|1908155:1942975|1921441_1921993_-|WP_014874848.1|DBSCAN-SWA
MYKLAAVFALMAGPALASGLEIAVEGEGANGTIKIDLFEDVAPKHVEQITALAAEGKYDGVVFHRVIEGFMAQTGDVEFGKLGGDMRRAGMGGSERSDLPAEFSDLEFDRGVVGMARSQDPDSANSQFFIMFAPGHFLNGQYTVVGKVTEGMDVVDAIKRGSGSQNGAVVGQPDVMKTVSVTE
>NC_018286|1908155:1942975|1938591_1938996_-|WP_014874864.1|DBSCAN-SWA
MTSSQQSAPAVNAYAANPYAGEVALRINGETLALKLTLGALATLETRLRTGSLIDLVTRFESGGFSAADVLALLAAGLQGGGHRLSEADLAAADIDGGPMQAARTAAQLLARSFALPGEAGAQVPGQGPGWVAP
>NC_018286|1908155:1942975|1931666_1935623_-|WP_014874858.1|DBSCAN-SWA
MATILLSAAGAALGGSVGGAVAGLSSVAIGRALGATVGRAIDSRLLGAGSEPVETGRVERFRLTHASDGQPIAQVYGRMRVGGQVIWASEFRETSTTSGGGGKGGGPRQPKVTSYSYDVSLAVAVCAGEVASIGRVWADGEEVAPKDLNMTVYRGTMDQLPDPVIEAVEGAGEVPAYRGTAYVVMENLALDRFGNRVPQFSFEVLRAEQPASSTYDLDLPQLVQGVALMPGTGEYALASTPVHYDHGPGQAKPANSHSPSGETDLVTSLTTLGEELPACGAASLIVSWFGNDLRCRACTVKPKVERQHIEGANMPWSVAGLTRTEAELIARQDDRPIYGGTPTDTSVIEAIRAMQAQGKRVMFYPFILMDQMAGNDLPDPWSGEPGQAHLPWRGRITLSRAPGQPGSPDGTATARMEVQQFFGTATAADFTVADGAVTYSGPLEDWGLRRFILHNAALCAAAGGVEAFCISSEMRGLTQIRDEAGFPAVAELRALTQEVRQILGPDTQIGYAADWSEYWGYQSPEGNRYFHLDPLWADEQIDFIGIDNYMPLSDWREGEEHLDAKAGAPNIYDQTYLRANIEGGEGYDWYYHSPEAEAAQIRTPITDGAYDEPWIWRYKDLRSWWSKPHHDRINGQRAALPTAWEPQSKPIWFTELGCAAIDKGTNQPNKFLDPKSSESKLPKFSDGQRDDMMQLAYLRALLGYWEEEGMNPVSEVYDGPMLDMSNAYVWAWDARPFPTFPNAVEVWSDGENYLRGHWLNGRVGQRTLASVLEEICAASGIAAIDVSDLPALVRGYAISDVGEARATLQPLLLRHGVDAIERDGLLRFRLRNGRQDAALDLAQLVEGQELDGVLEQTRAPEAELAGRMRLRFVEWGGRHDLRGEEAVLPDEATHAVSDNELPMALTRAEGRQVVERWLSEARMARDTLRLELPPSAMALGAGDVIRLPLAGAEAGPEVGSGAQARYRIDRVEQGAAQLIEAVRIEPENYHPAPVPEELPGVTAFAAPVPVLPLFMDLPLIGGDEVPHAPHLAVTAQPWPGSVALYGAQSDADYVLEEVVAAASTIAITNTVLPAGALGRWERGADLEVDMITGQFQSRDRTAVLNGANLVAIGDGSPGNWELLQFAKAELIAPGRYLLRDRLRGQQGSDARMPVAWPKGSYVVALDGTPQQITLAANQRGLSRHYRIGTARRPYDDPSYVHLEAAFAGEGLRPYAPVHLRQKGVLGSGAVGLDWIRRSRTDGDRWDLAEIPLGEDLERYRLRILRGSDVLREELLDSPGWSYPVAAQTADAVAPGDRVEVAQISARYGAGAATVLRLV
>NC_018286|1908155:1942975|1942357_1942975_-|WP_014874870.1|head,protease|DBSCAN-SWA
MRHDEHLEHKFARFGEDLTIGAEANDMVVISGYASLFGCVDGGGDLVQPHAYQASLDRLSKAGIAVKMLWQHDPAQPIGVWDVVREDARGLYVKGRILTRTQKGAEAAALIAVGALDGLSIGYRTRRATARKGGGRCLAELDLWEVSLVTFPMLPAARVTPTAQPVTAAKSTSAEPDLSDPGETPQIWREVIEMLRSGASLAPLG
>NC_018286|1908155:1942975|1913755_1914637_+|WP_044040688.1|DBSCAN-SWA
MTSDASQTNVDSPDRPLSLAQMAQQVLTTADGREKTALSRRHAAHWFSYRAGDAAKIEVGTASPPLHPARPDKPELLNPRDVPRRRPGSEAGRKALLHAVAHIELNAVDLHWDIIARFSHVPMPLGFFDDWVKAADEESKHFNLMCDCLEALGSYYGELPAHIGMWRAAEDTAEDLMGRLAVVPMVLEARGLDVTPGMIEVFRKAKLTQAVDALEVIYAEEVSHVAYGSKWFHFLCGRDNLDPKEVFHDLVGRYFHGHLKPPFNEEKRAEAGIPPDFYWPLADEIPVKPPALR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014874839.1|1908155_1909226_-|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_014874840.1|1909329_1913052_-	hypothetical protein	NA	NA	NA	NA
WP_014874841.1|1913152_1913614_+	peroxiredoxin	NA	NA	NA	NA
WP_044040688.1|1913755_1914637_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_014874843.1|1915042_1916374_+	peptidoglycan DD-metalloendopeptidase family protein	S5M424	Bacillus_phage	1.1e-17	44.3
WP_014874844.1|1916363_1916906_+	polymer-forming cytoskeletal protein	NA	NA	NA	NA
WP_014874845.1|1917148_1918393_+	calcium-binding protein	NA	NA	NA	NA
WP_014874846.1|1918634_1920131_+	calcium-binding protein	NA	NA	NA	NA
WP_162893394.1|1920218_1921154_-	DUF3179 domain-containing protein	NA	NA	NA	NA
WP_014874848.1|1921441_1921993_-	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	2.0e-40	57.7
WP_014874849.1|1921985_1922492_-	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	9.6e-42	55.0
WP_014874850.1|1922673_1923864_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_014880143.1|1924121_1924421_+	septum formation initiator-like protein	NA	NA	NA	NA
WP_014874852.1|1924723_1925737_+	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	NA	NA	NA	NA
WP_014874853.1|1925753_1927139_+	pyruvate dehydrogenase complex E1 component subunit beta	NA	NA	NA	NA
WP_014874854.1|1927151_1928486_+	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase	NA	NA	NA	NA
WP_168155301.1|1928817_1929873_+	hypothetical protein	NA	NA	NA	NA
WP_014874856.1|1930249_1931065_-	serine O-acetyltransferase	NA	NA	NA	NA
WP_014874857.1|1931357_1931654_-	hypothetical protein	NA	NA	NA	NA
WP_014874858.1|1931666_1935623_-	hypothetical protein	A0A0B5A7K5	Paracoccus_phage	5.7e-222	37.5
WP_014874859.1|1935622_1936093_-	peptidase	A0A1V0DYB6	Dinoroseobacter_phage	5.6e-28	47.1
WP_014874860.1|1936089_1937040_-	DUF2163 domain-containing protein	A0A0K0PVK1	Roseobacter_phage	1.5e-51	36.4
WP_014874861.1|1937039_1937672_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	5.9e-57	50.0
WP_014874862.1|1937687_1938344_-|tail	phage tail tape measure protein	D6PFD6	uncultured_phage	1.5e-10	33.5
WP_014874863.1|1938340_1938595_-|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_014874864.1|1938591_1938996_-	gene transfer agent family protein	NA	NA	NA	NA
WP_014874865.1|1939009_1939423_-|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_014874866.1|1939525_1939933_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_014874867.1|1939929_1940301_-|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_044040925.1|1940297_1940942_-	hypothetical protein	NA	NA	NA	NA
WP_014874869.1|1941124_1942309_-|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	2.2e-60	39.0
WP_014874870.1|1942357_1942975_-|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	3.2e-31	52.9