CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022196	Fusobacterium nucleatum subsp. vincentii 3_1_36A2, complete sequence	3 crisprs	csa3,cas4,cas9,cas1,cas2,csn2,DinG,WYL,DEDDh,cas3	0	15	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022196_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022196_1

944985-946274

TypeII

Consensus_repeat	Method
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	PILER-CR
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CRISPRCasFinder
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CRT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	PILER-CR

19 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NC_022196_1

>merge|NC_022196|1|944985-946274|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTTTTTCTTTTCTCGTAAACAATAAAATTCAGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTGCTTAAAACTTATAAAGAGACTATGGGTGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACACATTATTGGAAGTTGTGAAGGTGGCTACGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACGAAAAGGAGACAATAAATTTGTAATGTTAAGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTTTGTTTTCTTAAATCATCATATCTTCTTTGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACCTAAAAACTTACAAAAAAATACATTGAATAGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACAAAAAATAGCATTTTTCTAAAATCTTATAAGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACAAAAAAGAAGTAAATTACAGAGGTCAAAAAGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACGTGTACCTTTTGATTTAAGATACAGTTATTGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTCAAGAGATTGAATATTAGAAGAACATTGGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACAGAAATTCTTAGCACATCTTAAATCAATGGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTAATGATGTAAACGATATGTAAACACCTAGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACAAATAATTGACCTATTAAAAACTTTATGTTGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACATAGAAGTTGTAAAACATAGAGCAAGAGATGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTTTAGATACTTTATAAGTTTCGACTTCTACGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACCCAGTAATCATATTCAGAGCCTACTATTTGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTCATTACTCCAAGTTGTCCTTGTCTGTTCTGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACGTTTTGCTGGGTTTACTGTATACCAGCTATGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACGAAATTGAATTTGAAAGTATTAAGAATTCTGTTTGAGAGTAATGTTATCTTAAAAATACAGTCTAA

>NC_022196|1|1|944985-945746|PILER-CR
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTTTCTTTTCTCGTAAACAATAAAATTCA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TGCTTAAAACTTATAAAGAGACTATGGGTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ACATTATTGGAAGTTGTGAAGGTGGCTACG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GAAAAGGAGACAATAAATTTGTAATGTTAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTGTTTTCTTAAATCATCATATCTTCTTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CTAAAAACTTACAAAAAAATACATTGAATA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAATAGCATTTTTCTAAAATCTTATAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAAGAAGTAAATTACAGAGGTCAAAAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTGTACCTTTTGATTTAAGATACAGTTATT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCAAGAGATTGAATATTAGAAGAACATTGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AGAAATTCTTAGCACATCTTAAATCAATGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTAATGATGTAAACGATATGTAAACACCTAGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAATAATTGACCTATTAAAAACTTTATGTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ATAGAAGTTGTAAAACATAGAGCAAGAGAT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTAGATACTTTATAAGTTTCGACTTCTAC
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CCAGTAATCATATTCAGAGCCTACTATTTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCATTACTCCAAGTTGTCCTTGTCTGTTCT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTTTTGCTGGGTTTACTGTATACCAGCTAT


>NC_022196|1|1|944985-946274|CRISPRCasFinder
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTTTCTTTTCTCGTAAACAATAAAATTCA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TGCTTAAAACTTATAAAGAGACTATGGGTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ACATTATTGGAAGTTGTGAAGGTGGCTACG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GAAAAGGAGACAATAAATTTGTAATGTTAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTGTTTTCTTAAATCATCATATCTTCTTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CTAAAAACTTACAAAAAAATACATTGAATA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAATAGCATTTTTCTAAAATCTTATAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAAGAAGTAAATTACAGAGGTCAAAAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTGTACCTTTTGATTTAAGATACAGTTATT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCAAGAGATTGAATATTAGAAGAACATTGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AGAAATTCTTAGCACATCTTAAATCAATGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TAATGATGTAAACGATATGTAAACACCTAG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAATAATTGACCTATTAAAAACTTTATGTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ATAGAAGTTGTAAAACATAGAGCAAGAGAT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTAGATACTTTATAAGTTTCGACTTCTAC
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CCAGTAATCATATTCAGAGCCTACTATTTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCATTACTCCAAGTTGTCCTTGTCTGTTCT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTTTTGCTGGGTTTACTGTATACCAGCTAT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GAAATTGAATTTGAAAGTATTAAGAATTCT
GTTTGAGAGTAATGTTATCTTAAAAATACAGTCTAA

>NC_022196|1|1|944985-946274|CRT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTTTCTTTTCTCGTAAACAATAAAATTCA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TGCTTAAAACTTATAAAGAGACTATGGGTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ACATTATTGGAAGTTGTGAAGGTGGCTACG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GAAAAGGAGACAATAAATTTGTAATGTTAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTGTTTTCTTAAATCATCATATCTTCTTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CTAAAAACTTACAAAAAAATACATTGAATA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAATAGCATTTTTCTAAAATCTTATAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAAGAAGTAAATTACAGAGGTCAAAAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTGTACCTTTTGATTTAAGATACAGTTATT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCAAGAGATTGAATATTAGAAGAACATTGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AGAAATTCTTAGCACATCTTAAATCAATGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TAATGATGTAAACGATATGTAAACACCTAG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAATAATTGACCTATTAAAAACTTTATGTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ATAGAAGTTGTAAAACATAGAGCAAGAGAT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTAGATACTTTATAAGTTTCGACTTCTAC
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CCAGTAATCATATTCAGAGCCTACTATTTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCATTACTCCAAGTTGTCCTTGTCTGTTCT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTTTTGCTGGGTTTACTGTATACCAGCTAT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GAAATTGAATTTGAAAGTATTAAGAATTCT
GTTTGAGAGTAATGTTATCTTAAAAATACAGTCTAA

>NC_022196|1|2|945777-946208|PILER-CR
	TTTTTCTTTTCTCGTAAACAATAAAATTCA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TGCTTAAAACTTATAAAGAGACTATGGGTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ACATTATTGGAAGTTGTGAAGGTGGCTACG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GAAAAGGAGACAATAAATTTGTAATGTTAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTGTTTTCTTAAATCATCATATCTTCTTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CTAAAAACTTACAAAAAAATACATTGAATA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAATAGCATTTTTCTAAAATCTTATAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAAAAAGAAGTAAATTACAGAGGTCAAAAA
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTGTACCTTTTGATTTAAGATACAGTTATT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCAAGAGATTGAATATTAGAAGAACATTGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AGAAATTCTTAGCACATCTTAAATCAATGG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAACTAATGATGTAAACGATATGTAAACACCTAGGTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	AAATAATTGACCTATTAAAAACTTTATGTT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	ATAGAAGTTGTAAAACATAGAGCAAGAGAT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TTTAGATACTTTATAAGTTTCGACTTCTAC
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	CCAGTAATCATATTCAGAGCCTACTATTTG
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	TCATTACTCCAAGTTGTCCTTGTCTGTTCT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC	GTTTTGCTGGGTTTACTGTATACCAGCTAT
GTTTGAGAGTAATGTTATTTTAAATAGATTCAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022196.1\|WP_005890615.1\|952444_953683_+\|peptidase-T	unknown	unknown	gnl\|CDD\|235484
NC_022196.1\|WP_005888653.1\|943924_944245_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_022196.1\|WP_008797470.1\|930893_931208_+\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_005890612.1\|951149_952340_+\|nucleotidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|377535
NC_022196.1\|WP_008799283.1\|932866_933586_-\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_008799285.1\|938928_943032_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NC_022196.1\|WP_008797464.1\|943056_943935_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NC_022196.1\|WP_008797463.1\|944241_944904_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09644_csn2_CAS-II-A	gnl\|CDD\|213407
NC_022196.1\|WP_008799291.1\|950598_951132_+\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_008799289.1\|948276_949032_-\|DUF4241-domain-containing-protein	unknown	unknown	gnl\|CDD\|379427
NC_022196.1\|WP_008797468.1\|932259_932823_+\|elongation-factor-P	unknown	unknown	gnl\|CDD\|234788
NC_022196.1\|WP_008799284.1\|933735_936792_+\|TIR-domain-containing-protein	unknown	unknown	gnl\|CDD\|379328
NC_022196.1\|WP_005890617.1\|953689_955390_+\|YgiQ-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|274847
NC_022196.1\|WP_008797469.1\|931207_932260_+\|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	unknown	unknown	gnl\|CDD\|226829
NC_022196.1\|WP_005890608.1\|949896_950583_+\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184516
NC_022196.1\|WP_008799290.1\|949049_949769_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NC_022196.1\|WP_008799288.1\|947411_948116_-\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|224100
NC_022196.1\|WP_008797466.1\|936795_938622_+\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_008799286.1\|946324_946714_-\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_008799287.1\|946894_947398_-\|flavodoxin	unknown	unknown	gnl\|CDD\|273788

Protein	Function_ID	Function_description	E-value
NC_022196.1\|WP_005890612.1\|951149_952340_+\|nucleotidyltransferase-family-protein	gnl\|CDD\|377535	pfam05636, HIGH_NTase1, HIGH Nucleotidyl Transferase. This family consists of HIGH Nucleotidyl Transferases.	3.20348e-141
NC_022196.1\|WP_008799285.1\|938928_943032_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	5.32819e-119
NC_022196.1\|WP_008797464.1\|943056_943935_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	4.06985e-99
NC_022196.1\|WP_008797463.1\|944241_944904_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213407	cd09644, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	9.34368e-53
NC_022196.1\|WP_005890615.1\|952444_953683_+\|peptidase-T	gnl\|CDD\|235484	PRK05469, PRK05469, tripeptide aminopeptidase PepT.	0
NC_022196.1\|WP_008799284.1\|933735_936792_+\|TIR-domain-containing-protein	gnl\|CDD\|379328	pfam13676, TIR_2, TIR domain. This is a family of bacterial Toll-like receptors.	1.92309e-12
NC_022196.1\|WP_008799289.1\|948276_949032_-\|DUF4241-domain-containing-protein	gnl\|CDD\|379427	pfam14025, DUF4241, Protein of unknown function (DUF4241). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 205 and 315 amino acids in length. There is a conserved GDG sequence motif at the C-terminus.	7.09838e-66
NC_022196.1\|WP_008799288.1\|947411_948116_-\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	7.12566e-100
NC_022196.1\|WP_005890617.1\|953689_955390_+\|YgiQ-family-radical-SAM-protein	gnl\|CDD\|274847	TIGR03904, putative_radical_SAM_protein_YgiQ, uncharacterized radical SAM protein YgiQ. Members of this family are fairly widespread uncharacterized radical SAM family proteins, many of which are designated YgiQ. [Unknown function, Enzymes of unknown specificity].	0
NC_022196.1\|WP_008797469.1\|931207_932260_+\|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	gnl\|CDD\|226829	COG4394, EarP, Elongation-Factor P (EF-P) rhamnosyltransferase EarP [Translation, ribosomal structure and biogenesis].	0
NC_022196.1\|WP_008797468.1\|932259_932823_+\|elongation-factor-P	gnl\|CDD\|234788	PRK00529, PRK00529, elongation factor P; Validated.	9.72282e-91
NC_022196.1\|WP_005890608.1\|949896_950583_+\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184516	PRK14115, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	8.81261e-157
NC_022196.1\|WP_008799290.1\|949049_949769_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	3.62356e-18
NC_022196.1\|WP_005888653.1\|943924_944245_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.89823e-29
NC_022196.1\|WP_008799287.1\|946894_947398_-\|flavodoxin	gnl\|CDD\|273788	TIGR01752, Flavodoxin_1., flavodoxin, long chain. Flavodoxins are small redox-active proteins with a flavin mononucleotide (FMN) prosthetic group. They can act in nitrogen fixation by nitrogenase, in sulfite reduction, and light-dependent NADP+ reduction in during photosynthesis, among other roles. This model describes the long chain type, typical for nitrogen fixation but associated with pyruvate formate-lyase activation and cobalamin-dependent methionine synthase activity in E. coli. [Energy metabolism, Electron transport].	1.87188e-79

>NC_022196.1|WP_008797463.1|944241_944904_+|type-II-A-CRISPR-associated-protein-Csn2
MIFQYKGFNFKIDFEEKNIFSLIVENKRAYRKIIEDLVNNSNIEDGNIILSKNNKLVMPEKEIFVFSDYFNFDINKFVLNKYYKELKNLSENEFLNETLEIKEILKDYINKLIENNYSLKFEDDLDVSQILKAFSIKFERSEDLLLNLFEWLKILNEILGYEIFFFINIENFLSEDELLEFSKFIVYNKYKVVFLENFYRNKLSDNDNLIVIDNDLCEIF
>NC_022196.1|WP_005888653.1|943924_944245_+|CRISPR-associated-endonuclease-Cas2
MSYRFMRMLLFFDLPSVTNSDLKEYRKFRKFLIENGFSMLQESVYSKLLLHNTASINMVDKLQKNKPEKGSVCMLIITEKQYQKMILLIGELKGTFLETDERLVVL
>NC_022196.1|WP_008797464.1|943056_943935_+|type-II-CRISPR-associated-endonuclease-Cas1
MSGWRVIVITGRSKLDLRYNSISIRRDNGTDFIHIGEVNTLILETTTISITAALMCELIKQKVKVIFCDEKSNPHFELLPFYGSHDCSAKIKEQIAWTDFLKESLWTIIVTEKIENQMKLLKKLNKEEYKILQEYASQIEHNDNTNREGHSAKIYFSALFGNNFSRNKENSLNAFLNYGYQLLLSTFNKEIVANGYLTQIGIFHKNMFNYYNLSSDLMEPFRVIVDELAYKENPQKFEKDEKRKLQNILNLKFRINNVNHYLSDIIKIYTKSIFDALSANDLSLVRFFEDEL
>NC_022196.1|WP_008799285.1|938928_943032_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKQKFSDYYLGFDIGTNSVGWCVTDLDYNVLRFNKKDMWGSRLFDEAKTAAERRVQRNSRRRLKRRKWRLNLLEEIFSDEIMKIDSNFFRRLKESSLWLEDKNSKEKFTLFNDDNYKDYDFYKQYPTIFHLRDELIKNPEKKDIRLIYLALHSIFKSRGHFLFEGQNLKEIKNFETLYNNLISFLEDNGINKSIDKDNIKKLEKIICDSGKGLKDKEKEFKEIFNSDKQLVAIFKLSVGSSVSLNDLFDTDEYKKEEVEKEKISFREQIYEDDKPIYYSILGEKIELLDIAKSFYDFMVLNNILSDSNYISEAKVKLYEEHKKDLKNLKYIIRKYNKENYDKLFKDKNENNYPAYIGLNKEKGKKEVVEKSGLKIDDLIKVIKGYLPKPERIEEKDKTIFNEILNKIELKTILPKQRISDNGTLPYQIHEVELEKILENQSKYYDFLNYEENGVSTKDKLLKTFKFRIPYYVGPLNSYHKDKGGNSWIVRKEEGKILPWNFEQKVDIEKSAEEFIKRMTNKCTYLNGEDVIPKDSFLYSEYIILNELNKVQVNDEFLNEENKRKIIDELFKENKKVSEKKFKEYLLVNQIANRTVELKGIKDSFNSNYVSYIKFKDIFGEKLNLDIYKEISEKSILWKCLYGDDKKIFEKKIKNEYGDILNKDEIKKINSFKFNTWGRLSEKLLTGIEFINLETGECYSSVMEALRRTNYNLMELLSSKFTLQESIDNGNKEMNEVSYRDLIEESYVSPSLKRAILQTLKIYEEIKKITGRVPKKVFIEMARGGDETMKNKKIPARQEQLKKLYDSCGNDIANFSIDIKKMKSSLSSYDNNSLRQKKLYLYYLQFGKCMYTGREIDLDRLLQNNDTYDIDHIYPRSKVIKDDSFDNLVLVLKNENAEKSNEYPVKKEIQEKMKSFWRFLKEKNFISDEKYKRLTGKDDFELRGFMARQLVNVRQTTKEVGKILQQIEPEIKIVYSKAEIASSFREMFDFIKVRELNDTHHAKDAYLNIVAGNVYNTKFTEKPYRYLQEIKENYDVKKIYNYDIKNAWDKENSLEIVKKNMKKNTVNITRFIKEEKGQLFDLNPIKKGETSNEIISIKPKLYNGKEEKLNEKYGYYKSLNPAYFLYVEHKEKNKRIKSFERVNLVDVNNIKDEKSLVKYLIENKKLVEPRLIKKVYKRQVILINDYPYSIVALDSNKLMDFENLKPLFLENKYEKILKNVIKFLEDNQGKSEENYKFIYLKKKDRYEKNETLESVKDRYNLEFNEMYDKFLEKLDSKDYKNYINNKKYKNLLDVKEKFIKLNLFDKAFTLKSFLDLFNRKTMADFSKVGLTKYLGKIQKISSNVLSKNELYLLEESVTGLFVKKIKL
>NC_022196.1|WP_008797466.1|936795_938622_+|hypothetical-protein
MKKISNIIKHYFNKNLWIIYILGFVLSLIGSFQVYHGRYDNILKEISVISVSVLKLFLFVPIEGFTKQNPLAYELAIWVAPMSTLLATFSVFNKSYTAIKLKLTHFHKEHIIVMGYNDYSLSFMKNYIGLKNKKKILCVLPERTQENDIKALNKLGIITSHIDYMSGLNDENIRVSSEYNFASVNTIICFEDEPKNYGYLKLISELISKGKNKKEKTINVYVNTVNKYIKNIVQHKMDEIKIFDIKYFNIYDLIAYNLVNLKKFKLYETSGLKKEYFSFDDFSNSIGTPNILLIGFKNCGKSLFELAVNQTTINAKENMKITIVDRKISNIIEEYKATIRELKKVANIELIDGDINHITTQNKIRENHRKNPFTAVLFSTKNCAESLIFMDLLGEEIFKNVNTAVFCENIWENKPLIESIILKYPNITIFGELIDVLNFESITNEPLEIKAKEFNAYYNKISEKILNNTEQNISIEEQWNILSNIKKDSSRNQCMHQNVKEVLLEKIAQIEGFSSVEELLNTWKAMIDSVSTKEQINIIEKNSAMNYMSALEHKRWNNFYYMKNFVYSEKKDEVNCTHNSLIDDWDEFLYSDKREQVIYDFISVLSVK
>NC_022196.1|WP_008799284.1|933735_936792_+|TIR-domain-containing-protein
MVEIENTTKKKYKYDAFISYRHVEPDLTIAEILHDMIEKFNIPKHLRTVSNDGSLIDDKHVFRVFRDREELSTKDLSTMIEEAIANSENLIVICSKRTSLSPWCRKEVQLFKKIHGANNIIPILIEGEPDESFIDELKNLKATFINSENVEEEKNIELLAADIRPDEVKSPSFKGYEILQNSKDPKLNELTKKSLDILKKSEIYRIVASMLNVNYGDLKLRHQERYLKRIIYTSVAASIAMLIFVVSVTTLYLKSVVSERKANEQSSLMTLNMANEANLQGNRMLGVLIAQEAMKNVSPKMEKYNKLEAQYENILNNSLITLPFSNQFILPTESETASFGISSDSKWLISSGSFNNAIIWDLDNGGIKKTLTFESPVISIALSPNSKKSYIGTANNKIFEVNMENYEINNVFGNSTLPAVAMRISKNNKYLFALRNALILDVFDIQNQKKLYSFTFPIDNMITGFAENPQTNNFFILRKDNSITEYDINTGEALIVHASTTNPEKNFFRKMTITDNGTLFYSDIQENTESFIMKNLQSGQINRASNIRNFSSNIVVNKDATLLYVSSLNNFITRFDLSNLKPDEEINVPQRATYLDTKRTQYNESIKTMILSPDENTLAVVLNNMAIGAFSGVKNMTSDSSHEFILNEKSTHKASVDIIKFTPNSKKIITSANDYTIRVMDTESTMGKSQLLNGKIVASSRDKNSILILSGDKISKYNFDTNKEEFIATLDSKFLKVFQQFAITNDVSLVALSDSTNGASASVFDVKQDKKLYTTKSHTVKAGILPFISGLQFSNDGNFLFTLGPDNQLFIHDAKTGEFLFSLEDQENGEATSFIMSNDDNFVAINYITKKSTIFSLREKKIVQKIDGEVMAINSENNNIKAIYGQVDSKLFVIKPNNKVLYYADNKIKTATGTLKFNTINMSYDGKYYISSIPKNNTIITDLVTGEPVRTLYNSSNDFFISLPVISKDNKKVAYSESKDKVIIMNMYSTEELSKIATKILKGRQLTEAELNSIGRRE
>NC_022196.1|WP_008799283.1|932866_933586_-|hypothetical-protein
MKRKLFFILLLFLISSIYVFGENFPQKAKTVNDFIPKGWKKILTTNGDLNKDKLEDTVIVIEKEDKKNIKKNDGFGPEELNLNPRILLVLFKQKDGTYILASKNDKGFIKSEGNDNNPALMDTLDDIIIKNNVLKIVFNYFMSAGSWWTSTNVYIFRFQNNVFELIGYESNAYMRNTGEEEGTSINFSTNKAKITTGGNIFEEKENNPKDEWRYLKFEKKYILDEMTESTLDEILDIVY
>NC_022196.1|WP_008797468.1|932259_932823_+|elongation-factor-P
MKIAQELRAGSTIKIGNDPFVVLKAEYNKSGRNAAVVKFKMKNLISGNISDAVYKADDKMDDIKLDKVKAIYSYQNGDSYIFSNPETWEEIELKGEDLGDALNYLEEEMPLDVVYYESTAVAVELPTFIEREVVYTEPGLRGDTSGKVMKPARINTGFEIQVPLFVEQGEWIKIDTRNNEYVERVKK
>NC_022196.1|WP_008797469.1|931207_932260_+|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP
MEINSIDIFCEVIDNYGDVGVAYRLAREFKRLYPNKKLRFIINQTEEINLIKKSNDIEIIVYKDISKIENSADLIIETFGCKIPKEYMNKAFKDSKLIINLEYFSAEDWVDDFHLQESFLGGNLKKYFFIPGLSKKSGGILLDNEFLERKKRVEENKEYYLEKFGINEKYDLIASVFSYEKNFDSLIKELKKLDKKFLLLILSEKTQKNFIKYFDNNNNYDKIKFVKLPFFTYDKYEELLALCDFNLVRGEDSFVRALLLGKPFLWHIYPQDENTHIKKLESFLEKYCPNNKELKETFINYNINREDFSYFFKNFKEIEEHNKKYANHLIKNCNLIEKLIKFIENIGGKN
>NC_022196.1|WP_008797470.1|930893_931208_+|hypothetical-protein
MKKEILCIVIPILLITACTHSFGVGAGTRGRRSSVSTGTGISTGTKTQKINDNIMKEKAKTTVKKPTPKKVVGQNTIKNNKTEATGNTNKTGTTVKRVKQERQE
>NC_022196.1|WP_008799286.1|946324_946714_-|hypothetical-protein
MILFKILLMVLFCCVLPVVIVLKIWVYFATLHTEKKNELRTQKLLSYLPIKTVPELLKVLEAEAQKPKEYYFKTYYITTELHFNDVCLIQGEDNWIVCYTDSHAFTDEHYFQTEQEACEFFFHYYFNLL
>NC_022196.1|WP_008799287.1|946894_947398_-|flavodoxin
MKTIGIFYATLTKTTVGIVDEIEFFLKKDDFKTFNVKNGVKEIENFENLIFVTPTYQVGEAHAAWMNNLKKLEEIDFTGKVVGLVGLGNQFAFGESFCGGIKYLYDIVIKKGGKVVGFTSTDGYHYEETSIVKDDKFIGLALDEENQPNLTPKRIGDWITEIKKEFK
>NC_022196.1|WP_008799288.1|947411_948116_-|tRNA-threonylcarbamoyladenosine-dehydratase
MFLQRTELLIGSDNIEKLKNSNVIVFGLGGVGGATVEALIRAGIGNLSIVDFDTVDKTNLNRQIITTQSVIGKSKVEVAKDRILSINPNINLTIYNKKFFKENIDLFFKDKKYDYIVDAIDLITAKLDLIEFATNSKIPIISCMGTGNKLNPAKFKVADIEKTSVCPLAKIIRKELKKRRINKLKVVYSDETPRKPINLDGGREKTKNVGSISFVPPVAGMLLASEVIKDICEL
>NC_022196.1|WP_008799289.1|948276_949032_-|DUF4241-domain-containing-protein
MQPTKEWLEKWEKVKDKLHPNSNLEDYFTSKEIAGKEIDVMDIGPCSVPTGGFLVGDPLVYLGSKYEKEYFQKIPIGEFKTEVCVVKANDEDCDRYAAVRLKFNDNEISYFEEAMKGIEDLEDINEGDFFGFNVDAGLACICDKKLHDLYCEFYEKFAKENPDGNIYDDYFAKLFEESYKDNPKYQRDGGDWINWNIPNTNYHLPIFQSGFGDGAYPVYLAYDKDGNVCQLIVELIDIELAYSEIDEDDDE
>NC_022196.1|WP_008799290.1|949049_949769_-|Fic-family-protein
MNKILETLLEEKKIKLKRSLYHLTQINFSYNSNHIEGSQLTEEQTQYIYETNSFISDKEKAVSIDDINETINHFKCFDYILENINILDENLIKALHKILKNNTSDSQKDWFKVGDYKLRANFIGNTKTTNPSNVSKEMKKLLDEYNSKIKITFDDIVNFHYKFEAIHPFQDGNGRVGRLIMFKECLRNDIVPFIIDEEHKLFYYRGLKNYKEDKVYLIETCLSAEDKYIKLLNDLEIFK
>NC_022196.1|WP_005890608.1|949896_950583_+|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MKLVLIRHGESAWNLENRFTGWKDVDLSPKGVEEAKAAGKSLKEMGLVFDVAYTSYLKRAIKTLNIVLEEMDELYIPVYKSWRLNERHYGALQGLNKAETAKKYGDEQVHIWRRSFDVAPPSIDKNSEYYPKSDRRYANLADSDIPLGESLKDTIARVLPYWHSDISKSLQEGKNVIVAAHGNSLRALIKYLLNISNEDILNLNLTTGKPLIFEMDKDLKVLKAPESF
>NC_022196.1|WP_008799291.1|950598_951132_+|hypothetical-protein
MKKLILMSCLIVSFASFAGINDLPDNVERNIRSAVSSYSGSERRENYDWYKDSYLEMINRLDNSGIPEVDKQTIIKRLEAMYGGNYPKQLSRVNDEINDYKGLVNRIREEQNAVQQRTEAENQKSKEEINSILSSSSIPKADLDKIEQNAKAEYPNDYTLQKAYIKGAIKTYNDLKK
>NC_022196.1|WP_005890612.1|951149_952340_+|nucleotidyltransferase-family-protein
MFKNVVGLIVEYNPFHNGHLHHIQEIDRLFEDNIKIAVMSGDYVQRGEPSLINKFEKTKIALSQGVDIVIELPAFYSTQSAEIFAKSSVNLLNKLSCNYIVFGSESNDLDKLKRIATISLTKEFELSLRGFLAEGFSYPTAFSKALFDEKLGSNDILALEYLRAIKTINSKIEAYCIKREKTGYYDDEKDNFASATYIRKILLDYNKKKEDKLNKIKNLVPKFSYKILEENFGVFSCLRDFYDLIKYNIIKNHLELKDIQDLEIGLENRLYKYSLENLKFEDFFNEVLTKRITISRLQRILLHSLFGLTENVTERVKNKVPFVKILGFSARGQKYLNYLKKSENYSERKILTSNRNLKEILNEEDIELFNFNELCSQIYCIKSNYINIGYPIIKKD
>NC_022196.1|WP_005890615.1|952444_953683_+|peptidase-T
MDSKKYVTLKERFLKYVKFNTRSDEASETIPSTPSQMEFAKMLKKELEELGLSNIFINKACFVNATLPSNIDKKVATIGFIAHMDTADFNAEGINPQIVENYDGKDIVLNKEQNIVLKVDEFPNLKNYISETLITTDGTTLLGADDKSGIVEIIEAVNYLKEHPEIKHGDIKIAFGPDEEIGRGADYFDVKEFAADYAYTMDGGPVGELEYESFNAAQAKFKIKGVSVHPGTAKGKMINASLIASEIIEMFPKDEVPEKTEGYEGFYFLDEMKSNCEEGEVVYIIRDHDKAKFLAKKEFVKELVEKINKKYGREVVKLELKDEYYNMGEIIKDHMYVVDIAKQAMENLGIKPIIKPIRGGTDGSKISFMGLPTPNIFAGGENFHGKYEFVALESMEKATDVIVEIIKLNAER
>NC_022196.1|WP_005890617.1|953689_955390_+|YgiQ-family-radical-SAM-protein
MKFLPTTKEEMKNLGWDSIDVLLISGDTYLDTSYNGSALIGKWLVEHGFKVGIIAQPEVDVPDDITRLGEPNLFFAVSGGCVDSMVANYTATKKRRQQDDFTPGGVNNKRPDRAVLVYSNMIRRFFKGTTKKIVISGIESSLRRITHYDYWTNKLRKPILFDAKADILSYGMGEMSMLQLADALKNGKDWKNIRGLCYLSKEIKEEYLSLPSHSECLADKDKFIEAFHTFYLNCDPITAKGLCQKCDDRYLIQNPPSESYSEEIMDKIYSMEFARDVHPYYKKMGTVRALDTIKYSVTTHRGCYGECNFCAIAIHQGRTIMSRSQSSIVEEVKNIAETPKFHGNISDVGGPTANMYGLECKKKLKLGACPDRRCLYPKKCPHLQVNHNNQVELLKKLKKIPNIKKIFIASGIRYDMILDDNKCGQMYLKEIIKDHISGQMKIAPEHTEDKILGLMGKDGKSCLNEFKNQFYKINNELGKKQFLTYYLIAAHPGCKDKDMMDLKRYASQELRVNPEQVQIFTPTPSTYSTLMYYTEKDPFSNQKLFVEKDNGKKQKQKDIVTEKRRK

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Crispr_ID: NC_022196_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022196_2

1488023-1488102

Orphan

Consensus_repeat	Method
TTATCTTCTCCCATTGATAATTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022196_2

>merge|NC_022196|2|1488023-1488102|CRISPRCasFinder
TTATCTTCTCCCATTGATAATTATTTTAATAAAAAAAATAAAAATAAAAGTGTTTAATTATCTTCTCCCATTGATAATTA

>NC_022196|2|2|1488023-1488102|CRISPRCasFinder
TTATCTTCTCCCATTGATAATTA	TTTTAATAAAAAAAATAAAAATAAAAGTGTTTAA
TTATCTTCTCCCATTGATAATTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_022196.1\|WP_008797059.1\|1492568_1492919_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NC_022196.1\|WP_005914099.1\|1491854_1492478_-\|lysophospholipid-acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|225032
NC_022196.1\|WP_008799610.1\|1485743_1486565_-\|sirohydrochlorin-cobaltochelatase	unknown	unknown	gnl\|CDD\|227159
NC_022196.1\|WP_005914185.1\|1477750_1479040_-\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NC_022196.1\|WP_005912939.1\|1486728_1487193_+\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_008799613.1\|1489721_1491632_-\|methionine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237028
NC_022196.1\|WP_008799618.1\|1497995_1501064_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_022196.1\|WP_008799607.1\|1480965_1481559_+\|uracil-DNA-glycosylase-family-protein	unknown	unknown	gnl\|CDD\|381683
NC_022196.1\|WP_008799616.1\|1495597_1496869_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NC_022196.1\|WP_005912952.1\|1479630_1480674_-\|C4-dicarboxylate-TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270387
NC_022196.1\|WP_008799615.1\|1494940_1495576_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_022196.1\|WP_008799608.1\|1481695_1483000_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_022196.1\|WP_008799611.1\|1488175_1489060_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NC_022196.1\|WP_008799609.1\|1483924_1485484_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|224720
NC_022196.1\|WP_020789318.1\|1483002_1483677_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_022196.1\|WP_008799614.1\|1492987_1494724_-\|signal-peptide-peptidase-SppA	unknown	unknown	gnl\|CDD\|273226
NC_022196.1\|WP_008799617.1\|1496886_1497996_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_022196.1\|WP_008799612.1\|1489072_1489693_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_022196.1\|WP_008799606.1\|1479060_1479531_-\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NC_022196.1\|WP_008797063.1\|1487361_1488000_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|225439

Protein	Function_ID	Function_description	E-value
NC_022196.1\|WP_008797059.1\|1492568_1492919_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	7.38023e-31
NC_022196.1\|WP_008799608.1\|1481695_1483000_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.46848e-44
NC_022196.1\|WP_008799610.1\|1485743_1486565_-\|sirohydrochlorin-cobaltochelatase	gnl\|CDD\|227159	COG4822, CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism].	2.04632e-131
NC_022196.1\|WP_005914185.1\|1477750_1479040_-\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	7.45059e-138
NC_022196.1\|WP_008799613.1\|1489721_1491632_-\|methionine--tRNA-ligase	gnl\|CDD\|237028	PRK12267, PRK12267, methionyl-tRNA synthetase; Reviewed.	0
NC_022196.1\|WP_008799618.1\|1497995_1501064_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_022196.1\|WP_008799607.1\|1480965_1481559_+\|uracil-DNA-glycosylase-family-protein	gnl\|CDD\|381683	cd10033, UDG_like, uncharacterized family of the uracil-DNA glycosylase superfamily. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Uracil may arise from mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations; thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other. UDG family 1 is the most efficient uracil-DNA glycosylase (UDG, also known as UNG) and shows a specificity for uracil in DNA. UDG family 2 includes thymine DNA glycosylase which removes uracil and thymine from G:U and G:T mismatches, and mismatch-specific uracil DNA glycosylase (MUG) which in Escherichia coli is highly specific to G:U mismatches but also repairs G:T mismatches at high enzyme concentration. UDG family 3 includes Human SMUG1 which can remove uracil and its oxidized pyrimidine derivatives from, single-stranded DNA and double-stranded DNA with a preference for single-stranded DNA. Pedobacter heparinus SMUG2, which is UDG family 3 SMUG1-like, displays catalytic activities towards DNA containing uracil or hypoxanthine/xanthine. UDG family 4 includes Thermotoga maritima TTUDGA, a robust UDG which like family 1, acts on double-stranded and single-stranded uracil-containing DNA. UDG family 5 (UDGb) includes Thermus thermophilus HB8 TTUDGB which acts on double-stranded uracil-containing DNA; it is a hypoxanthine DNA glycosylase acting on double-stranded hypoxanthine-containing DNA except for the C/I base pair, as well as a xanthine DNA glycosylase which acts on both double-stranded and single-stranded xanthine-containing DNA. UDG family 6 hypoxanthine-DNA glycosylase lacks any detectable UDG activity; it excises hypoxanthine. Other UDG families include one represented by Bradyrhizobium diazoefficiens Blr0248 which prefers single-stranded DNA and removes uracil, 5-hydroxymethyl-uracil or xanthine from it.	5.97798e-97
NC_022196.1\|WP_008799616.1\|1495597_1496869_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.07846e-64
NC_022196.1\|WP_005912952.1\|1479630_1480674_-\|C4-dicarboxylate-TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270387	cd13669, PBP2_TRAP_TM0322_like, Periplasmic component of TRAP-type C4-dicarboxylate transport system TM0322 from Thermotoga maritima and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the hyperthermophilic bacterium Thermotoga maritima TRAP-type C4-dicarboxylate transport system TM0322 and its closely related proteins. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.52471e-140
NC_022196.1\|WP_008799615.1\|1494940_1495576_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.96347e-09
NC_022196.1\|WP_008799609.1\|1483924_1485484_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	4.02354e-74
NC_022196.1\|WP_008799611.1\|1488175_1489060_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	2.57281e-163
NC_022196.1\|WP_020789318.1\|1483002_1483677_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.23841e-78
NC_022196.1\|WP_008799614.1\|1492987_1494724_-\|signal-peptide-peptidase-SppA	gnl\|CDD\|273226	TIGR00705, Protease_4, signal peptide peptidase SppA, 67K type. This model represents the signal peptide peptidase A (SppA, protease IV) as found in E. coli, Treponema pallidum, Mycobacterium leprae, and several other species, in which it has a molecular mass around 67 kDa and a duplication such that the N-terminal half shares extensive homology with the C-terminal half. This enzyme was shown in E. coli to form homotetramers. E. coli SohB, which is most closely homologous to the C-terminal duplication of SppA, is predicted to perform a similar function of small peptide degradation, but in the periplasm. Many prokaryotes have a single SppA/SohB homolog that may perform the function of either or both. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	5.06084e-88
NC_022196.1\|WP_005914099.1\|1491854_1492478_-\|lysophospholipid-acyltransferase-family-protein	gnl\|CDD\|225032	COG2121, COG2121, Uncharacterized protein conserved in bacteria [Function unknown].	9.182e-85
NC_022196.1\|WP_008799617.1\|1496886_1497996_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.60418e-53
NC_022196.1\|WP_008799612.1\|1489072_1489693_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.0415e-07
NC_022196.1\|WP_008799606.1\|1479060_1479531_-\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	1.50502e-30
NC_022196.1\|WP_008797063.1\|1487361_1488000_+\|OmpA-family-protein	gnl\|CDD\|225439	COG2885, OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane].	1.60714e-57

>NC_022196.1|WP_008797063.1|1487361_1488000_+|OmpA-family-protein
MKNKKIIASCMLALSLVGCTGFEAGNGGYTAGGAAGGAAVGALAGQIIGKDTKGTLIGAAVGSLLGMGWGAYRDNQERELKAKLQGTQAQVRKDGNALVINLPGGVTFASDSANISSGFYSALNGIAQSLNNYPETRIQVNGYTDNTGKDAHNQELSQRRANAVAQYLIAQGVASNRIVANGFGSSNPVASNSTQEGRLQNRRVEIKILPAQ
>NC_022196.1|WP_005912939.1|1486728_1487193_+|hypothetical-protein
MKKEWAFLKLLTTKGYRKVVLIPLAFCLGIFLYYLYIDFTGGEVDKTVYDDGSIRISAQSDLGSCKLPKILDVLNIPIHDELKIRNYNVYLDKDENINSVEIYCSTDKDGNEIIEWYKEKLNSTNDAKGIWNNFEMDVSFNKFSNLVSIVLKKQ
>NC_022196.1|WP_008799610.1|1485743_1486565_-|sirohydrochlorin-cobaltochelatase
MSKKALFMVHFGTTHNDTKELTIDKMNKKFADEFKDYNLFTAYTSRIVLKKLKDRGEALSTPIRVLNSLADQGYEELLVQTSHIIPGIEYENLVREVNSFSNKFKSIKIGKPLLYYIDDYKKCVEALADEYVPKNKKEALVLVCHGTDSPLATSYAMIEYVFDEYGYDNAFVVCTKAYPLMGTLLKKLKKHDIEEVRLAPFMFVAGEHAKNDMAITYKKELEENGFKVNQVILKGLGEFDAIQNIFLNHLKTAIEKDDEDIADFKKEYSEKYL
>NC_022196.1|WP_008799609.1|1483924_1485484_+|glycosyltransferase-family-39-protein
MFSTKRKDIFVLTILSFFALLSLVWIREIDSSEARNLISAREILQNSNWWTPTLNGHFYFENPPLPVWITAFVMMITHSHSEVVLRLPNMLCCIFTVLFLYRSMIRIKKDRLFAFLCSFVLLSTFMFIKLGAENTWDIYTYSFAFCASLAFYVYIKYGEKKNLYRMGILLVLSFLSKGPVGFYSLFIPFLLAHYIIFPKEIFRKKTFSVIFSIIIAIAIASIWGISMYLNHGNYFLDVIKNEVLAWRTKHHHSFIFYTDFVVYMGSWLFFSIYILFKIPKEKESKIFYLWTILVLIFISLIEMKKKKYGFPLYLTSSITIGQLCIYYFRKPYLELKKREKTLLIVQQVFLIVVVIGSLGFLAYFGFYKKEISFGLFFLYAILHLLFLFLFAVGYTEISYAKRVIIFTGLTMLLVNFSSSWILVSKYMQNNLLRFRIPISQEVLENPAPIYSQGFDIEDVWKLGKEIKSLNKNIPDERVIFFLGKEEPKELLKAYEIKKVYNYQKVTHDMERIYLLEKIY
>NC_022196.1|WP_020789318.1|1483002_1483677_-|response-regulator-transcription-factor
MNKILIIEDDKNIQRLLALELRHKNYFVDSAYDGEQGIEIFSKNSYDVVLLDLMLPKKSGKEVCQELRKLADTPIIVITAKDSVLDKVELLDLGANDYICKPFAMEELLARIRVSTRNKENSNNKHFYLENEIKMDILAKKVFLNEEEIALTKTEFLILEYFMKNKGLSCSREKIIIDVWGYDFDGEEKIVDVYINSLRKKIDSKSKYIHTIRGFGYIFQYKED
>NC_022196.1|WP_008799608.1|1481695_1483000_-|HAMP-domain-containing-histidine-kinase
MKKISKELLKTYYWVIALFAIFSIFIIVNFSVYLWKENQNDIKVIEEFVEYQMSELENREDLDYLSKEWILKKILDKSPKIRDVYLEIFYNGKKYTKPPYLPDKEHNFLDYYSVTKFYQIKGFDEIKVKITRRNVRDRLLILNAFTSFVFFLLFCLYVIIRIQKKFFDKFKNSLDNLKIFTQDYNLDSEIRIHSEENFIEFSILQKAFKNMLIRLKEQSQLQIDFVNNASHELKTPIFVIKGYVDMLNDWGKDDKEVLDEGLIVLKKEIQNMQELTEKLLFLAKSKNLVVEKNNTNLDNALKEVIDNLSFAYPKQKINYTSSEIFIESDIALLKLLFKNLIENAIKYGKDNPINIELKKEKKVKVIIEDFGVGISEKALPHIFERFYREDEARNREIKSYGLGLSIVKEIIALLNIDIQIESQLGKGTKITLLF
>NC_022196.1|WP_008799607.1|1480965_1481559_+|uracil-DNA-glycosylase-family-protein
MNRDEKLKKIIEEIKNDDENKKYTEQGIDPLFSAPEKARIVIVGQAPGLKAQENRLYWKDKSGDKLRIWTGIDEKTFYSSNLLAIIPMDFYYPGKGKSGDLPPRKDFGDKWHNKILELLPNVELFILIGKYAQGFYLKGKLKDNLTDTVKAYKEYLPKFFPIVHPSPLNIGWLKKNPWFEEEVVPTLKEMVTKIMEK
>NC_022196.1|WP_005912952.1|1479630_1480674_-|C4-dicarboxylate-TRAP-transporter-substrate-binding-protein
MKKILSLIFLSLLTLALVACGGKKEEATKGEGEAKKEARVIKVTTKFVDDEQTAKSLVKVVEAINQRSNGSLELQLFTSGTLPIGKDGMEQVANGSDWILVDGVNFLGDYVPDYNAVTGPMLYQSFEEYLRMVKTPLVQDLNAQALEKGIKVLSLDWLFGFRNIEAKKAIKTPEDMKGLKLRVPTSQLYTFTIEAMGGNPVAMPYPDTYAALQQGVIDGLEGSILSFYGTKQYENVKEYSLTRHLLGVSAVCISKKCWDSLTDEERTIIQEEFDKGALDNLTETEKLEDEYAQKLKDNGVTFHEVDAEAFNKAVAPVYEKFPKWTPGIYDKIMENLTQIREDIKNGK
>NC_022196.1|WP_008799606.1|1479060_1479531_-|TRAP-transporter-small-permease
MKDFFKKFELYIGSIFISITTVVVIMNVFTRYFLKFTYFWSEEVAVGCFVWTIFLGTAAAYREKGLIGVEAIVVLLPEKIRDIVEFLTYILLTILSGLMCVFSFTYVSSSSKITAALELSYGYINISIVISFALMTLYSIIFTVGSFKKAFLKKDN
>NC_022196.1|WP_005914185.1|1477750_1479040_-|TRAP-transporter-large-permease
MEALYPVIVLFVLFFLNIPIAFALMGSALFYFIFLNTTMSMDMVIQQFVTSVESFPYLAVPFFIMVGSVMNYSGISEELMNMAEVLAGHMKGGLAQVNCLLSAMMGGISGSANADAAMESKILVPEMIKKGFSKEFSAAVTAASSAVSPVIPPGTNLILYALIANVPVGDMFLAGYTPGILMTAAMMVTVYIISKKRGYEPSRERMARPVEILKQAIKSIWALAIPFGIIMGMRIGIFTPTEAGGVAVFFCFLVGFFIYKKLKLHHIPIILMETVKNTGAVMIIIASAKVFGYYMTLERIPQFITNSLMNFTDNKLVLLMVINVLLLFIGMFIEGGAALVILAPLLVPAVRELGVDPLHFGVIFIVNIMIGGLTPPFGSMMFTVCSIVGVRLEAFIKEVWPFIVALLIVLLLVTYSESIALFIPNLFLK
>NC_022196.1|WP_008799611.1|1488175_1489060_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKVTKAVIPAAGLGTRVLPATKALPKEMLTIVDKPSLQYIVEELVASGITDILIITGRNKNSIEDHFDFSYELENTLKNDHKSELLDKVSHISNMANIYYVRQNMPLGLGHAILKAKSFIGDEPFVIALGDDIIYNPEKPVTKQMIEKYELYGKSMIGCQEVAKEDVSKYGIAKLGDKLDEATFQMLDFLEKPSVDNAPSRTACLGRYLLSGKVFKYLEETKPGKNSEIQLTDGILAMMKDEEEVLAYNFIGKRYDIGSKFGLLKANIEFGLRNDETKEDIKEYLKNLDIEKV
>NC_022196.1|WP_008799612.1|1489072_1489693_-|tetratricopeptide-repeat-protein
MGKIISKKDEEFFENVEYFSEIIDRINDIQANNNYSDEEMNNDLDVALWRAFVYINLWSYKGYAKAEKILKRVEKKGRENPIWCYRYGVSIARLRKYEEALKYFILGTEVDSMYPWNWLELGRLYYKFGELDNVYKCIEKGLELVPNDYEFLTLKDDVKNDRGYFYSINHYINEEVDKTEDRELDYSDDKEWEKFIKETHYGEKCL
>NC_022196.1|WP_008799613.1|1489721_1491632_-|methionine--tRNA-ligase
MKKNFFVSTPIYYVNGDPHVGSAYTTIAADVINRYNKAMGMDTHFMTGLDEHGQKVEQAAEQNGYTPQAWTDKMTPNFKNMWAALDIKYDDFIRTTEDRHKKAVKRILDTVNAKGDIYKGEYEGKYCISCETFFPENQLNGSNKCPDCGKELRVLKEESYFFKMSKYADALLKHIEEHPDFILPHSRRNEVISFIKQGLQDLSISRNTFTWGIPIDFAPGHITYVWFDALTNYLTSAGFENDDKKFDKFWNNARVVHLIGKDIIRFHAIIWPCMLLSAGIKLPDSIVAHGWWTSEGEKMSKSRGNVVNPYDEIKKYGVDAFRYYLLREVNFGTDGDYSTKGIIGRLNSDLANDLGNLLNRTLGMYKKYFNSVIVASSTAEPIDDEIKTMFDDIIKDVEKYMYLFEFSRALETIWKFISRLNKYIDETMPWSLAKDEAKKGRLATVMNILCEGLYKIAFLIAPYMPESAQKISNQLGIDKDITNVKFDDIKEWNIFKEGHKLGEASPIFPRIEIEKKEVVESKKELKVENPIDIKEFNKVEIKVVEILDVDKVKDTDKLLKFKVFDGEFERQIISGLAKFYPDFKKLIGEKVLAVVNLKFTKLKGEISQGMLLTTEDKNRVSLIKIDKSIEAGAIIS
>NC_022196.1|WP_005914099.1|1491854_1492478_-|lysophospholipid-acyltransferase-family-protein
MEENKKYRILGTLLYYLLRIISSTLRIEIINKYGIDMQKPHIYGFWHSKLFITPIFFKDVEKKLAMSSPTKDGELVSVPLEKMGYILVRGSSDKNQISSTISLLKYLKKGYSIGTPLDGPKGPKEKAKKGLLYLSQKTSVPLVPVGILYSKKWILKKTWDQFEIPKPFSKVKIFLGEPIIIKDEDDLDKYTEIVENGINSLNNQIEF
>NC_022196.1|WP_008797059.1|1492568_1492919_-|YbaB/EbfC-family-nucleoid-associated-protein
MVRKLKGAKTAGGNQADIVKQAQVMQQQMLEVQEQLKSKEVSSSVGGGAVSVKVNGQKELIEVKLSDEVLKDAANDKEMLEDLILTAVKDAMAKAEELAEGEMAKVTGGINIPGLF
>NC_022196.1|WP_008799614.1|1492987_1494724_-|signal-peptide-peptidase-SppA
MKILHYLKRFILFVIKEILSFFIKLFLFLFVAGIIISAIIKSFEEKPTVAIKNKAYVLINLADSYNERLLKSNLFEDDSINFYTLLQSIENVSYDDRVEGIILKINGDSLSYAQSEELAHELSMARAANKKIIAYFENVGRKNYYLASYANEIYMPSANSTNVNIYPYFREEFYIKQLADKFGVKFNIIHVGDYKSYMENLASSTMSKEAREDTVRVLDKNYNNFLDVVSLNRKINRDDLDKIIKDGELVAASSVDLMNNNLIDKYAYWDNVISMVGGKDKIITVQEYTKNYYKEGSMTDSNNIIYVIPLEGDIVESETEVFSGEENINVSETLEKLNIAKENDKIKAVVLRVNSPGGSALTSDIIAEKVKELAEEKPVYVSMSSVAASGGYYISANANKIFVDRNTITGSIGVVSILPDFSKLITDNGVNIEKISDGEYSDLYSVDSFTEKKYNKIYNSNLKVYEDFLNVVSKGRKIDKEKLKTIAEGRIWTGDEAIKIGLADEIGGLNETIYALAEDNDMDEYAIVVAKDKLEIGNIYKKYSRYIKMNTKDLIKEKIFKDYLYNKPVTYLPYDVLD
>NC_022196.1|WP_008799615.1|1494940_1495576_+|TetR/AcrR-family-transcriptional-regulator
MNSDIDKKNLILEKAKDMIITESYSSLSISKLTSELSISKGSFYTYFPSKDKMLGEILDEYIKNIIIFKNNLLENSKNIDDCLDYYINSILSLSDEELKLELVITNLKRNYEVFNEENFKKLKIIACTMIDFIKEVLNKYKKDINIDKKDIEKCSKMIFSIAEVFLVMENVDFNSDRFSFKTLDEVKKMYRSDDMKEHLEFIKKSIKKIIY
>NC_022196.1|WP_008799616.1|1495597_1496869_+|TolC-family-protein
MKKILTVFLLMTNIILARDLTLEQAIDLSLSNSKEMKISEKNLDISKLNVNKAIKNALPSVTYAGAYTVGEHERQILTQSERDRVNKKRGYTQNLKLTQPLFTGGAVTAGIKGAKAYENIASYSYLQSKIQNRLDTIKIFSDIINAERNLEALKYSEGVLLKRYQKQEEQLKLRLITKTDVLQTEYSIEDIRAQMINIKNVIDTNMEKLYIRTGINKSEPLNLIPFDIPNNFSEKINLNSDLKQAINESLSAKLAEEQVKVASATRMAAVGDLLPKVNAFASYGTGERTTFERSYKDGEWTGGIEVSWKVFSFGSDLDNYRVAKLQEEQEELKETSTKENIEINVRSAYLNVLSLEKQIASQSKALEAAKVNFELNQEKYDAGLISTVDYLDFENTYRRARIAYNKVLLDYYYAFETYRSLLI
>NC_022196.1|WP_008799617.1|1496886_1497996_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKLLTIFLAASLLLVACGKDKEEKKETTKQEATVTDEQKSVKSVEVAEVKTREMSKLFDSSAVWEPLAKVDFSTDKGGTVKKIFKKNGEFVKKGEVIVKLSDAQTEADFLQAKANYQSATSNYNIARNNYQKFKTLYDKQLISYLEFSNYETTFTSAQGNLEVAKAAYMNAQDSYGKLIARAEISGVVGNLFIKEGNDIAAKETLFTILNDSQMQSYVGIAPEAISKVKIGDSIKVRIDALGKDYTAKITELNPIADNTTKNFKVKLTLDNPDKEIKDGMFGNVIIPVGQSSVLSIEDEAIVTRDLVNYVFKYENGKVRQIEVKVGATNLPYTEISSPEIKEGDKIVVKGLFGLQDNDNVEIKNEVNK
>NC_022196.1|WP_008799618.1|1497995_1501064_+|efflux-RND-transporter-permease-subunit
MSLAGISIRRPVATTMVMVSFIFIGLLAMFSMKKELIPDINIPVVTISTTWNGAVAEDVETQVTKKIKDSLSNVEAIDKIQTVSSYGSSSVVVNFDFGVNTNDKVTQIQREVSKIANDLPKDANTPIVRKVDAATGSMTAIIAFNSDNKTALNTFIKEKLKPRLESLAGIGEVTIAGNPEKQLQIQVDSDKLSAYNLSPMELYNIIRTAVTTYPIGKLSTGNKDMIIRFMGELDYIDQYENILISSDGNTLRLKDVANVVLTTEDPDRLGYLKGKDSIVVLLSKSSDGDTIGLNSAAFKVIEEMKPYMPAGTEYSIELDNSENINSSISNVTSSAIQGLVLATIILFAFLKSFRTTILISLALPVAIIFTFAFLSMRGTTLNLISLMGLSIGVGMLTDNSVVVVDNIYRHITELNSPVLEAAENGTEEVTFSVIASALTTMVVFIPILFIPGLAREFFRDMSYAIIFSNLAAIIVAITMIPMLASRFLNRKSMKTEDGRLFKKVKARYLKIIHWAYTHKGKTVFIMVFLFFFSIFVGPKLLKFEFMPKQDEGKYSLMAELQNGTDIEKAKRIARELENIVKNEPHTKSYLMLVSTSNISINADVGKKGTRKESVFSIMDDVRKQAKNVLDARISLSNQFSGGRSTKDVEFLIQGMNQDEIKQFGKQILKKLQSYDGIVDLSSTLDPGIIELRINIDRDKITSYGINPTVVAQTLSYYMLGGDKSNTATLKTDSEEIDVLIRLPKDKRNDVNILQSLNIKVGDNKFVKLSDVATIQYAEGTSKINKKNGIYTVTISANDGGVGLGAIQQKMIEEFNSLNPPSSISYSWGGQTENMQKTMSQLSFALSISIFLIYALLASQFESFIMPIIIIGSIPLALIGVIWGLVVTGQSIDIMVMIGVILLAGVVVNNAIVLIDFIKTMRIRGHDKEYSVMYSCETRLRPILMTTMTTVFGMMPMALGLGEGSEFYRGMAITVIFGLSFSTILTLVLIPVLYSVVDDFTTKLITKIKNISNKSKKKGVNNG

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Crispr_ID: NC_022196_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022196_3

1816326-1816406

Orphan

Consensus_repeat	Method
AGAAGATATGTTCATATAGCAGTGAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022196_3

>merge|NC_022196|3|1816326-1816406|CRISPRCasFinder
AGAAGATATGTTCATATAGCAGTGAACAAGTTAATCAAAAGAAATGCTATTCAAGAAGATATGTTCATATAGCAGTGAACA

>NC_022196|3|3|1816326-1816406|CRISPRCasFinder
AGAAGATATGTTCATATAGCAGTGAACA	AGTTAATCAAAAGAAATGCTATTCA
AGAAGATATGTTCATATAGCAGTGAACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_022196.1\|WP_008796908.1\|1803908_1804691_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187604
NC_022196.1\|WP_008799848.1\|1804710_1807149_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_022196.1\|WP_008799859.1\|1819894_1820092_-\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_008796909.1\|1802544_1803699_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380570
NC_022196.1\|WP_020975303.1\|1813260_1813719_-\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|224854
NC_022196.1\|WP_008799847.1\|1801643_1802531_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223633
NC_022196.1\|WP_008799863.1\|1822257_1822908_-\|DUF2313-domain-containing-protein	unknown	unknown	gnl\|CDD\|378379
NC_022196.1\|WP_008799849.1\|1807513_1809253_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_022196.1\|WP_008799858.1\|1819496_1819880_-\|hypothetical-protein	unknown	unknown	unknown
NC_022196.1\|WP_008799850.1\|1809264_1811064_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_022196.1\|WP_008799857.1\|1819060_1819510_-\|DUF1353-domain-containing-protein	unknown	unknown	gnl\|CDD\|377774
NC_022196.1\|WP_008799846.1\|1800668_1801643_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119323
NC_022196.1\|WP_020789257.1\|1816990_1818529_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NC_022196.1\|WP_020975305.1\|1818662_1819049_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|377457
NC_022196.1\|WP_020789258.1\|1816492_1816927_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341213
NC_022196.1\|WP_008799864.1\|1822900_1823965_-\|baseplate-J/gp47-family-protein	unknown	unknown	gnl\|CDD\|377414
NC_022196.1\|WP_008799860.1\|1820151_1820661_-\|M15-family-metallopeptidase	unknown	unknown	gnl\|CDD\|350620
NC_022196.1\|WP_005913285.1\|1811131_1811389_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|223305
NC_022196.1\|WP_008799853.1\|1814408_1816280_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|182066
NC_022196.1\|WP_020975306.1\|1820774_1821497_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_022196.1\|WP_008796908.1\|1803908_1804691_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187604	cd05346, SDR_c5, classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.14803e-112
NC_022196.1\|WP_008799848.1\|1804710_1807149_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.76376e-12
NC_022196.1\|WP_008799863.1\|1822257_1822908_-\|DUF2313-domain-containing-protein	gnl\|CDD\|378379	pfam10076, DUF2313, Uncharacterized protein conserved in bacteria (DUF2313). Members of this family of proteins comprise various hypothetical and putative bacteriophage tail proteins.	3.02109e-09
NC_022196.1\|WP_008796909.1\|1802544_1803699_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380570	cd06347, PBP1_ABC_LivK_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.	2.01086e-151
NC_022196.1\|WP_020975303.1\|1813260_1813719_-\|IS200/IS605-family-transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.94295e-46
NC_022196.1\|WP_008799847.1\|1801643_1802531_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|223633	COG0559, LivH, Branched-chain amino acid ABC-type transport system, permease components [Amino acid transport and metabolism].	5.86402e-82
NC_022196.1\|WP_008799849.1\|1807513_1809253_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.84186e-132
NC_022196.1\|WP_008799850.1\|1809264_1811064_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.49104e-163
NC_022196.1\|WP_008799857.1\|1819060_1819510_-\|DUF1353-domain-containing-protein	gnl\|CDD\|377774	pfam07087, DUF1353, Protein of unknown function (DUF1353). This family consists of several hypothetical bacterial proteins of around 100 residues in length. The function of this family is unknown.	3.52784e-26
NC_022196.1\|WP_008799846.1\|1800668_1801643_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	3.19918e-78
NC_022196.1\|WP_020789257.1\|1816990_1818529_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_022196.1\|WP_020975305.1\|1818662_1819049_-\|phage-holin-family-protein	gnl\|CDD\|377457	pfam05105, Phage_holin_4_1, Bacteriophage holin family. Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination. This family also includes TcdE/UtxA involved in toxin secretion in Clostridium difficile. The 1.E.10 family is represented by Bacillus subtilis phi29 holin; 1.E.16 represents the Cph1 holin; and the 1.E.19 family is represented by the Clostridium difficile TcdE holin. Toxigenic strains of C. difficile produce two large toxins (TcdA and TcdB) encoded within a pathogenicity locus. tcdE, encoded between tcdA and tcdB, encodes a 166 aa protein which causes death to E. coli when expressed, and the structure of TcdE resembles holins. TcdE acts on the bacterial membrane. Since TcdA and TcdB lack signal peptides, they may be released via TcdE either prior to or subsequent to cell lysis.	2.40561e-29
NC_022196.1\|WP_020789258.1\|1816492_1816927_+\|hypothetical-protein	gnl\|CDD\|341213	cd17493, toxin_TenpN, type III toxin-antitoxin system toxin TenpN and similar proteins. TenpN-like toxin component of a type III toxin-antitoxin (TA) system, which consists of a ribonuclease (RNase) toxin that processes its structured and specific cognate RNA antitoxin, which in turn then directly inhibits the toxin. TA systems have been associated with many important phenotypes, like phage resistance, maintenance of genomic islands, and formation of bacterial persister cells.	4.13755e-29
NC_022196.1\|WP_008799864.1\|1822900_1823965_-\|baseplate-J/gp47-family-protein	gnl\|CDD\|377414	pfam04865, Baseplate_J, Baseplate J-like protein. The P2 bacteriophage J protein lies at the edge of the baseplate. This family also includes a number of bacterial homologs, which are thought to have been horizontally transferred.	1.17274e-60
NC_022196.1\|WP_008799860.1\|1820151_1820661_-\|M15-family-metallopeptidase	gnl\|CDD\|350620	cd14845, L-Ala-D-Glu_peptidase_like, L-Ala-D-Glu peptidase, also known as L-alanyl-D-glutamate endopeptidase. This L-Ala-D-Glu peptidase family includes L-alanyl-D-glutamate peptidase (bacteriophage T5) (also known as L-alanoyl-D-glutamate endopeptidase), and Ply118 and Ply500 L-Ala-D-Glu peptidase. Bacteriophage endolysin degrades the peptidoglycan of the bacterial host from within, leading to cell lysis and release of progeny virions. The bacteriophage endolysin Ply118 cleaves between L-Ala and D-Glu residues of Listeria cell wall peptidoglycan. This family belongs to the MEROPS peptidase M15 subfamily C.	1.62479e-27
NC_022196.1\|WP_005913285.1\|1811131_1811389_-\|50S-ribosomal-protein-L28	gnl\|CDD\|223305	COG0227, RpmB, Ribosomal protein L28 [Translation, ribosomal structure and biogenesis].	1.3519e-19
NC_022196.1\|WP_008799853.1\|1814408_1816280_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|182066	PRK09765, PRK09765, PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional.	3.73985e-135

>NC_022196.1|WP_008799853.1|1814408_1816280_+|PTS-sugar-transporter-subunit-IIA
MEIKDLLKKDLMIMDLKATTKMEAIDEMVAKLKEKNIISDEVAFKDLILKREEKSSTGLGEGIAMPHAKTSVVNTPAVLFARSNKGIDYDALDGEPVYIFFMIAASEGAHDLHIETLAKLSKMLLNDDFTNGLKTCKSPDEVYALVDKYSEKEQETSKEEIKEVQNTNKKKILAVTACPTGIAHTYMAEAALKEAGEKLGVDVKVETNGADGIKNNLTTNDINEAVGIIVAADKKVETARFNNRKVIVTSTADAIKNAETLIKKVLNNEAPIFKAETSDNSEEDTQETDSIGRIIYKSIMSGVSNMLPFVIGGGILLALSFVVERFMGENQLFKLLFDVGAGAFHFLIPILAGFIAMSIADKPGFMPGAVAGYMASQGAGFLGGLIGGFIAGYSVIFLKKMTKNMSKQFDGMKSMVIYPIFSLAITGVLMYFIIGPIFTKINLIVANWLNNLGTVNAVVLGAILGGMMSVDMGGPINKAAYTFSIGVFTDTGNGAFMAAVMAGGMVPPLAIALAMTLFKNNFDEKEKQSTISNFILGLSFITEGAIPFAAKEPVKVIGSCVIGAAIAGGLTQFWNVSAPAPHGGIFVIPAMPSIHSAVFFVVSIAIGAVISGVIFGVLRGKKK
>NC_022196.1|WP_020975303.1|1813260_1813719_-|IS200/IS605-family-transposase
MDKNSLAHTKWNCKYHIVFTPKYRRQAIYGKIKKDIGAILRKLCEFKGVEIIEASACVDHIHMLVSIPPKIAVSTFMGYLKEKSSLMIFDRYANLKYKYGNRTFWCRGYYVDTVGRNKERIAQYIKNQIEEDKIMDQMTLKEYFNPFNVEKK
>NC_022196.1|WP_005913285.1|1811131_1811389_-|50S-ribosomal-protein-L28
MQRCEITGTGLISGNQISHSHRLTRRVWKPNLQVTTLVVNGSPIKVKVCARTLKTLKGASETEVMRILKANIATLSERLLKHLNK
>NC_022196.1|WP_008799850.1|1809264_1811064_+|ABC-transporter-ATP-binding-protein
MAKKKNQNEDSIKNFKKAVSNFISLLGEKKVPFLISIISNTISTILVVSIPWVSALAIDDIVKILNDTTVTDKWNAVFSFIIKPISALGIIAALIFALNYLQEYISAILGEQVAQSLRVKLSKKFTKLPMNFFDTNQVGDILSKLTTDIEKVAEVIGTSFTRFVYSFLIIILVIFMLFNINAKLTLIVLAILLISVVVTYYVSNLTQKIFSRDVTSLSELSSITEEALTGNLVIQSYNKQKDIIDTLDKSIEKQYSAAKTLEFTVFSIYPSIRFITQIAFVISAVISAVLVINGHLTLGLAQAFLQYVTQISDPVTTAAYIINSLQNALVSVERIYDILELPEEVDLTEDTHLLDNTKGQIVFENVSFGYTKDKLLMKNVNFTAKAEQMVAIVGPTGAGKTTLINLLMRFYDVNGGRILFDGVDISKVSRKELRANFGMVLQDTWLFKGTIAENISYGKPDATREEIIEAAKLAKCDSFIRKLPQGYDTIITSENGMVSQGEQQLLTIARTILPNPKVMILDEATSSIDTKTEKDIQAVISELMKGRTSFVIAHRLSTIRNADLILVMKDGDIVEQGNHDELLKINGIYANLYNTQFNQ
>NC_022196.1|WP_008799849.1|1807513_1809253_+|ABC-transporter-ATP-binding-protein
MKLLRTYIKENIGTLSLSVIFLTFNTFATLAIPFEISNIINQGIMKKNIDMVYSTSIKMVAILIFGTVTGIIANHFVALFATNFSKKNRKMLIRNIETLTLDQVSDFGVASLVTRMSNDNNNAQRLIVAFFQMILPSPIMATISIFLTIKLSPSLALIPLFTILIFACAIVLTLFKSLPYILKVQKKLDRMTLVLRERFIGAKIIRAFDNSEKEKERFNNIGQDYADNYIIINKKFALLSPMAFALMSVIITLIIFFGAMKVLNNTLEIGSITAIVEYSLTTIAALIMSSMVLVQMPKAVVSIERIEEVLAVTSEIRDSEDLKDNSYYEGILKQNPISLTFDNVCFRYKGAEKQILKNISFSIKAGERFAIVGATGSGKSTIAKVLLRLNDIESGKILINNVNTLDLPLRCLRNQISYIPQKAYIFSGTIKDNFRFTNKNMTDEEMTEIAKVAQSYDFINSLPDKFNSFVAQGGTNFSGGQKQRLSIARALSKEANIYLFDDSFSALDYATDAKLRKELKTFLKDKITIIIAQRLNTIADADKIIVLKDSEITGMGTHQELLESNQEYIELAKSQGILE
>NC_022196.1|WP_008799848.1|1804710_1807149_-|tetratricopeptide-repeat-protein
MKDDMLKKIEDLYDLDKHQEIIDMIEALPAEQLNNELIGQLGRAYNNIQNYEKAIEILKSIEVEEGNTMRWNYRIGYSYYYLDDYENAEKCFLKAHEIDPEDEEIKNYLLNVYIELSKQVIDKDDSQENQDKAVEYALKSKEYITTDDDRIQCDSYLAWLYDKIGAYDLAEELLKSVISAGRDDVWVNSEYGYCLGELNKLEESLEHYLRAKELGRNDGWIYSQIGWTYRLLKKYEEALESDFKAQEMGQNDAWINVEIGICYKELEKYEEAIKYYLEANKMQEGKNVWLLSDMAWVYGVMGNNDEELKYLEEVKKLGRDDEWIYSEYGKVYYKLEQYEKALKFFNKAKKLGQNDAWINVQIARCYKGLEKNEDALKAYLKAEKFENDDIWLLSEIAWLYDGIGKYKEGLKYLKKIEKLGRDDCWFNTEYGFCLMRMQKYDKAIEKYKHALELKEELNEEIYLNCQLGFCYRLLEKYEEALKYHLKGQELGRNDAWINIEIGLCYKELENYEKALEYYLVAYEQDKEDTWLLSDIGWIYNELEKYEDGLQFLLKSNELGREDSWIYAEIGQCLGRLGKYTEGIEKLKKALEILDEDKTNENRQERIFINSEIGWLYGKIENSDPNEALHYLYAARDLGRDDQWLNAEIGWELGYNDKDKDEEAVKYFERSIELGRDDEWVWARVANIYFDLERYEDALKAYNRAYELEGAYKEGKDSLYICSIGRTLRRLGRYEEAVEKLLESRRLSLEEGDGVDLEDLELAHCYAVLGDKEKAEEYMKLSLDALGTYAEEEYLKKQFDEIKEMINVLSKPS
>NC_022196.1|WP_008796908.1|1803908_1804691_-|SDR-family-NAD(P)-dependent-oxidoreductase
MEENRVKGKIAFISGASSGIGKATAEKLAQMGVNLILCARRENILNELKENLEKKYGIKVKNLVFDVRNYNDVLKNINSLDDEWKKIDILVNNAGLAVGLEKFYEYNMEDVDKMVDTNIKGFTYIANTILPLMIATDKVCTVVNIGSVAGEIAYPNGSIYCATKFAVRAISDAMRSELIDKKIKVTNIKPGLVDTEFSLVRFRGDKTKADNVYKGIEPLYAEDIADTIAYVVNLPEKIQITDLAITPLHQANAIHIYKEK
>NC_022196.1|WP_008796909.1|1802544_1803699_-|ABC-transporter-substrate-binding-protein
MKKKLLTTLLGASLLLIACGGEKVEDKPTATEAETIKIGAMGPLTGSVAIYGISATNGLKLAIDEINANGGILGKQVELNLLDEKGDSTEAVNAYNKLVDWGMVALVGDITSKPSVAVAEVAAQDGIPMITPTGTQLNITEAGSNVFRVCFTDPYQGEVLAKFTKDKLAAKTVAVMSNNSSDYSDGVANAFVAEAEKQGIQVVAREGYSDGDKDFKAQLTKIAQQNPDVLFIPDYYEQDGLIAIQAREVGLKSVIVGSDGWDGVVKTVDPSSYAAIENVYFANHYSTKDSNERIQNFIKNYKEKYNDEPSAFSALSYDTAYLLKAAIEKAGTTDKEAVAKAIKEIQFEGITGQLTFDEKNNPVKSITIIKIVNGDYTFDSVVSK
>NC_022196.1|WP_008799847.1|1801643_1802531_-|branched-chain-amino-acid-ABC-transporter-permease
MEFLLQIINGLQIGSIYALVSLGYTMVYGIAQLINFAHGDIIMIGAYTSLFSIPLFTSLGLPIWATVIPAIIVCAVIGCLAERIAYRPLRNSPRISNLITAIGVSLFLENVFMKIFTPNTRSFPKIFDQAPISFGANIHISFGAIVTIVITLVLSIGLQLFMKKTKYGKAMIATSQDYAASELVGINVDRTIQLTFAIGSGLAAVGSVLYVSAYPQIQPLMGSMLGIKAFVAAVLGGIRILPGAVLGGFILGIVESLTRAYLSSQLADAFVFSILIIVLLFKPTGILGKNVKEKV
>NC_022196.1|WP_008799846.1|1800668_1801643_-|branched-chain-amino-acid-ABC-transporter-permease
MDKNKKISYITTYVLLIVLYFILFSLINSGFISRYQVGILILILINVILVASLNVTVGCLGQITLGHAGFMSIGAYTAALLTKSGFLSGYPGYIVALIIGGLVAGLIGFIIGIPALRLTGDYLAIITLAFGEIIRVLIEYFKFTGGAQGLTGIPRVNNFTLIYFITIFSVIFMYSIMTSRHGRAVLAIREDEIASGASGINTTYYKTFAFVLSAIFAGIAGGIYAHNLGILGAKQFDYNYSINILVMVVLGGMGSFTGSILSAIVLTILPEVLRSFAEYRMIVYPLILIIMMLFRPKGLLGREEFQISKVISYFTKKRGEADGK
>NC_022196.1|WP_020789258.1|1816492_1816927_+|hypothetical-protein
MKFCFLTDKFFDLYKECEEIEKKNNRPYATVCLLKYNNFYFAIPIRHNIKHQYAIFTDKEKTKGLDLSKTLIIKDLNFVVQNRTAFISQNEYSQLIQKETFIISKLNSYIKKYIKALKHQNIKKNYLLCSMSCLKYFHKELNIE
>NC_022196.1|WP_020789257.1|1816990_1818529_+|glutamine-hydrolyzing-GMP-synthase
MKKGGIVILDFGSQYNQLIARRVREMGVYAEVVPFHEDVDKILAKEPKGIILSGGPASVYAEGAPTLDIKLFQKNIPILGLCYGMQLITHLHGGKVARADKQEFGKAELELDDKNHILYKNIPNKTIVWMSHGDHVTEMAPDFKIIAHTDSSIAAIENSDKNIYAFQYHPEVTHSQHGFDMLKNFVFGIAKAEKNWSMENYIESTVKQIKERVGNKQVILGLSGGVDSSVAAALINKAIGKQLTCIFVDTGLLRKDEAKQVMEVYAKNFDMNIKCINAEERFLSKLAGVTDPETKRKIIGKEFVEVFNEEAKKIEGAEFLAQGTIYPDVIESVSVKGPSVTIKSHHNVGGLPEDLKFELLEPLRELFKDEVRKVGRELGIPDYMVDRHPFPGPGLGIRILGEVTKEKADILREADAIFIEELRKADLYNKVSQAFVVLLPVKSVGVMGDERTYEYTAVLRSANTIDFMTATWSHLPYKFLEKVSNRILNEVKGINRLAYDISSKPPATIEWE
>NC_022196.1|WP_020975305.1|1818662_1819049_-|phage-holin-family-protein
MVFLVKLGAYFIAFLIWLIGGWDTLAKVLFGLMFLDYLTGLIVGYKMQNLNSKRAFKGLRKKLLILVILCGASLMHKLVPDLAFRTLVGMFYCATELLSIVENVAKVGVPIPKKLKKALEQLREEKEE
>NC_022196.1|WP_008799857.1|1819060_1819510_-|DUF1353-domain-containing-protein
MEKTKLKLEFLSNKKAVLLQDYIYSINGYDIKVFRGFITDGASVPKSLQWLYNPYGKYINAAVIHDYLYSTYNNTGINRTLADKIFNFIMKETGIDNRTRRKFYMAVKCFGETSWKTKLQNEGYKDRAIIDRTKEAKEYYAYWYKKLKL
>NC_022196.1|WP_008799858.1|1819496_1819880_-|hypothetical-protein
MKDLINKAIGYLASFSVEQWIWIAVAGLILIYLIYNRKQYVNVFRQSVIFAEESFNHGENGKKLEAAVNFILFRTSSLPWVARIIIIKFISRKRMIDIIEKTLQKFSDIFANGYKVDIKGNEEDGEN
>NC_022196.1|WP_008799859.1|1819894_1820092_-|hypothetical-protein
MEAFVERMITEKDELQDKVTKLENFVNGEKFEELKGLEQVYLKEQLTHMRAYLSVLRQRINFYNK
>NC_022196.1|WP_008799860.1|1820151_1820661_-|M15-family-metallopeptidase
MYTLSQTSLDKLKGVHPNLVNFLKELILISPWDFKITAGVRTAAEQNLEYQKGRTLPGIKVTKVDGYKQKSNHQTKFDGLGYAADIGVLVKEKVIEKVKENGKEVEKEIEKTVYKGSWKDFHYYQDIYDTAKKAGLLEKYGIEWGGNCWKSFKDAPHWQIKGADKVAFK
>NC_022196.1|WP_020975306.1|1820774_1821497_-|hypothetical-protein
MKTINFYKKDKLIFSVYAESLEDVLKSPLSYFPAYTADVVITDVSYQYPIYKDDTLREMTREEKVRAGIDVTLEDGEIIKDKKIITVPKPSGNPKYLSWNKEKGLWLLDNEREYQDYMNLIDDLKAKSLAYGFDYKVDGKEHRQKCRDKDITLLASNVTFMLAEKTVYGKEKPITWYFYDNFGLKLDLEQSLILASYGKTFTQSVYDTEHFFKTKVNPKEVSKAEFENKRKEIHNALAKG
>NC_022196.1|WP_008799863.1|1822257_1822908_-|DUF2313-domain-containing-protein
MNDRLIKKVSKIARNSLQQDLIRTLDLMCEYAKNDIQKYKELLFMAFFNEQQIKNYERFMNLEFKKGWSLQDRKDRIIYTLLSKNIFTPHVLKEQAKIFTNGEIEVIENYNDYSFIIKFTSVVGIPSNLDNFKNFIHINKPAHLNFSIEFRYNTHNQVAYLLHNSLKLKTHKEIYDTRLYEDSEVVGKYHKHIEINKLKNDDLKTKTHKEIYDERR
>NC_022196.1|WP_008799864.1|1822900_1823965_-|baseplate-J/gp47-family-protein
MKDKIELRNNFLDNLKNPLSKMEGTFNFDIAATFGITTEEVYKELEFWEKQTFIDIATEDEYVDKHALMFGVKRRLGTKAKGIVKVTGRANSVIEENTIFLNRDGIKYKSLRKEYLSPTGIAEIEIECLSEGKVGNAAIGEITTFEIQNSNIYSVINEKEIINGYDKEPNSVLVARAKEKATRPAHSGNIYDYEQWAKEVDGVGKVLVKPLWNGNGTVKVLIANYNNDIADSSLIQKVRDRIQSDNGRPVGADVTVESFKAKTIKIEVNIILKSGYAISDIKEKIESLLKAVIKTGSATFEKDNKSVLSINRLEKAILEIEGINDNFVKVNNSNSNIEIAEDEMLIVGTVIINE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022196_1	1.9\|945549\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945549-945578	30	MK554696	Fusobacterium phage Fnu1, complete genome	97303-97332	1	0.967
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MN276049	Acinetobacter phage BS46, complete genome	83962-83986	3	0.88
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MN694566	Marine virus AFVG_250M779, complete genome	15525-15549	3	0.88
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	MN013077	Klebsiella phage vB_KaeM_KaOmega, complete genome	93132-93161	4	0.867
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	MN693456	Marine virus AFVG_25M411, complete genome	40663-40692	4	0.867
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MH333064	Klebsiella phage Mineola, complete genome	140062-140086	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MN434095	Klebsiella pneumoniae phage JIPh_Kp122, complete genome	130231-130255	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MN101229	Klebsiella phage KPN5, complete genome	38382-38406	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MG751100	Klebsiella phage KP1, complete genome	130849-130873	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	NC_028686	Klebsiella phage JD18, complete genome	129435-129459	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MK421971	Klebsiella phage vB_KpnM_GF, partial genome	126654-126678	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	LR877331	Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1	88215-88239	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MN101226	Klebsiella phage KPN2 HKu-2019, complete genome	89932-89956	4	0.84
NC_022196_3	3.1\|1816354\|25\|NC_022196\|CRISPRCasFinder	1816354-1816378	25	MN101225	Klebsiella phage KPN1, complete genome	6849-6873	4	0.84
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	MN693441	Marine virus AFVG_25M481, complete genome	441-470	5	0.833
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP045225	Clostridioides difficile strain TW11 plasmid p_TW11, complete sequence	36165-36198	5	0.853
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP047287	Proteus cibarius strain G11 plasmid p52, complete sequence	23106-23139	5	0.853
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP053373	Proteus cibarius strain G32 plasmid pG32-51, complete sequence	19417-19450	5	0.853
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP047341	Proteus cibarius strain ZF1 plasmid pZF1-cfr, complete sequence	13732-13765	5	0.853
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP045009	Proteus cibarius strain ZF2 plasmid pZF2-cfr, complete sequence	31062-31095	5	0.853
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	1388793-1388822	6	0.8
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	288247-288276	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	55693-55722	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	25155-25184	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	282969-282998	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	151689-151718	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	268690-268719	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	151689-151718	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	339490-339519	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	151197-151226	6	0.8
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	MN693180	Marine virus AFVG_25M318, complete genome	41776-41805	6	0.8
NC_022196_1	1.8\|945483\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945483-945512	30	NC_031931	Flavobacterium phage Fpv2, complete genome	4943-4972	6	0.8
NC_022196_1	1.8\|945483\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945483-945512	30	KU599877	Flavobacterium phage Fpv1, complete genome	4944-4973	6	0.8
NC_022196_1	1.8\|945483\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945483-945512	30	NZ_CP053689	Arthrobacter citreus strain NEB 577 plasmid unnamed1, complete sequence	165910-165939	6	0.8
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP017994	Planktothrix agardhii NIES-204 plasmid plasmid3 DNA, complete sequence	31131-31160	6	0.8
NC_022196_1	1.16\|946011\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	946011-946040	30	NC_011311	Aliivibrio salmonicida LFI1238 plasmid pVSAL840, complete sequence	73890-73919	6	0.8
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	768118-768147	6	0.8
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	768134-768163	6	0.8
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MK284528	Bacillus phage DK3, complete genome	3081-3110	6	0.8
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MK284526	Bacillus phage DK1, complete genome	2918-2947	6	0.8
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP007647	Lactobacillus salivarius strain JCM1046 plasmid pMP1046A, complete sequence	48949-48982	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP020859	Lactobacillus salivarius strain ZLS006 plasmid unnamed1, complete sequence	200339-200372	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_007930	Lactobacillus salivarius UCC118 plasmid pMP118, complete sequence	26012-26045	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP017108	Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence	152313-152346	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_003042	Clostridium perfringens str. 13 plasmid pCP13, complete sequence	16214-16247	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_LT604075	Lactobacillus salivarius isolate LPM01 plasmid II	184340-184373	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	CP002037	Lactobacillus salivarius CECT 5713 plasmid pHN3, complete sequence	26223-26256	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_022551	Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence	2601-2634	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_021183	Clostridium pasteurianum BC1 plasmid pCLOPA01, complete sequence	50763-50796	6	0.824
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_AP014865	Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK1, complete sequence	274219-274252	6	0.824
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP043636	Empedobacter brevis strain SE1-3 plasmid pSE1-3-20kb, complete sequence	19552-19581	7	0.767
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP043637	Empedobacter brevis strain SE1-3 plasmid pSE1-3-14kb, complete sequence	6902-6931	7	0.767
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP050068	Klebsiella aerogenes strain 035 plasmid p35, complete sequence	340731-340760	7	0.767
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP020848	Klebsiella variicola strain KPN1481 plasmid pKPN1481-1, complete sequence	93518-93547	7	0.767
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP043927	Klebsiella quasipneumoniae subsp. quasipneumoniae strain M17277 plasmid p17277A_477, complete sequence	150725-150754	7	0.767
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP021699	Klebsiella pneumoniae strain AR_0158 plasmid tig00000727, complete sequence	42051-42080	7	0.767
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP015439	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence	55610-55639	7	0.767
NC_022196_1	1.6\|945351\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945351-945380	30	MN694695	Marine virus AFVG_250M866, complete genome	36517-36546	7	0.767
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	NZ_CP041069	Bacillus megaterium strain KNU-01 plasmid pKNU_01_5, complete sequence	42925-42954	7	0.767
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	NZ_CP032531	Bacillus megaterium NCT-2 plasmid pNCT2_3, complete sequence	25069-25098	7	0.767
NC_022196_1	1.8\|945483\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945483-945512	30	AP014049	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12A-MedDCM-OCT-S34-C33, * SEQUENCING IN PROGRESS *	11358-11387	7	0.767
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP014045	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12-MedDCM-OCT-S26-C148, * SEQUENCING IN PROGRESS *	3066-3095	7	0.767
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP014054	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S33-C14, * SEQUENCING IN PROGRESS *	29512-29541	7	0.767
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP014053	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S29-C16, * SEQUENCING IN PROGRESS *	29525-29554	7	0.767
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP014060	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S45-C20, * SEQUENCING IN PROGRESS *	29512-29541	7	0.767
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP014055	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S41-C174, * SEQUENCING IN PROGRESS *	242-271	7	0.767
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP014052	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S27-C13, * SEQUENCING IN PROGRESS *	10150-10179	7	0.767
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	AP014058	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S42-C22, * SEQUENCING IN PROGRESS *	10157-10186	7	0.767
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	MK448388	Streptococcus satellite phage Javan259, complete genome	6053-6082	7	0.767
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	NZ_LR215032	Mycoplasma gallopavonis strain NCTC10186 plasmid 2	73677-73706	7	0.767
NC_022196_1	1.17\|946077\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	946077-946106	30	NC_019924	Clostridium phage phi8074-B1, complete genome	28952-28981	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	JX194239	Staphylococcus phage SA11, complete genome	77480-77509	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MT080584	UNVERIFIED: Staphylococcus phage vB_SauM_EW15, complete genome	119178-119207	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MT080590	UNVERIFIED: Staphylococcus phage vB_SauM_EW27, complete genome	16694-16723	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	KY779848	Staphylococcus phage qdsa001, complete genome	78754-78783	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	KX532239	Staphylococcus phage StAP1, complete genome	58773-58802	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	LC492751	Staphylococcus phage KSAP7 genomic DNA, compelete genome	45424-45453	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	LC492752	Staphylococcus phage KSAP11 genomic DNA, compelete genome	45244-45273	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MT080587	UNVERIFIED: Staphylococcus phage vB_SauM_EW20, complete genome	80329-80358	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	AP019522	Staphylococcal phage MR003 DNA, complete genome	81166-81195	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NC_022090	Staphylococcus phage vB_SauM_Remus, complete genome	45127-45156	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	KP881332	Staphylococcus phage Stau2, complete genome	51020-51049	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MT080588	UNVERIFIED: Staphylococcus phage vB_SauM_EW22, complete genome	56552-56581	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MT080595	UNVERIFIED: Staphylococcus phage vB_SauM_EW41, partial genome	37804-37833	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NC_020877	Staphylococcus phage vB_SauM_Romulus, complete genome	45127-45156	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MK721199	Enterococcus phage vB_EfaS_Ef5.1, complete genome	28367-28396	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MK721200	Enterococcus phage vB_EfaS_Ef5.3, complete genome	28659-28688	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MH814918	Acinetobacter phage AJO2 DNA polymerase (AJO2_38) gene, partial cds	1367-1396	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	348343-348372	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NZ_CP014351	Borrelia hermsii HS1 isolate Browne Mountain plasmid cp28, complete sequence	21903-21932	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MK448753	Streptococcus phage Javan407, complete genome	30249-30278	7	0.767
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	KJ473423	Acinetobacter phage vB_AbaP_Acibel007, complete genome	12257-12286	7	0.767
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	CP037991	Bacillus mycoides strain TH26 plasmid unnamed1, complete sequence	107329-107362	7	0.794
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	KP027447	Staphylococcus phage phiIPLA-C1C, complete genome	114625-114658	7	0.794
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_015919	Borreliella bissettii DN127 plasmid lp54, complete sequence	119-152	7	0.794
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	MN694663	Marine virus AFVG_250M439, complete genome	105-138	7	0.794
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	MN694663	Marine virus AFVG_250M439, complete genome	59606-59639	7	0.794
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP020426	Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence	4568-4601	7	0.794
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP038624	Arsenophonus nasoniae strain FIN plasmid pArsFIN12, complete sequence	10017-10046	8	0.733
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	KY979109	Salmonella phage SHP1, complete genome	40600-40629	8	0.733
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NC_019500	Enterobacteria phage Bp7, complete genome	29747-29776	8	0.733
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	KX171213	Staphylococcus phage vB_SscM-2, complete genome	72560-72589	8	0.733
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NC_047767	Staphylococcus phage vB_SscM-1, complete genome	72559-72588	8	0.733
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP017574	Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence	310909-310938	8	0.733
NC_022196_1	1.6\|945351\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945351-945380	30	NZ_CP041068	Bacillus megaterium strain KNU-01 plasmid pKNU_01_4, complete sequence	15289-15318	8	0.733
NC_022196_1	1.6\|945351\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945351-945380	30	CP041516	Bacillus aryabhattai strain KNU10 plasmid unnamed, complete sequence	38802-38831	8	0.733
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	NZ_AP017563	Pseudanabaena sp. ABRG5-3 plasmid ABRG53c, complete sequence	129878-129907	8	0.733
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	NZ_KP342511	Enterococcus faecium isolate N12-493 plasmid pEfm12493, complete sequence	137308-137337	8	0.733
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	NC_014031	Bacillus megaterium QM B1551 plasmid pBM600, complete sequence	22986-23015	8	0.733
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	MN657074	Psychrobacter sp. strain ANT_P37 plasmid pA37P2, complete sequence	9536-9565	8	0.733
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	NC_022880	Enterococcus mundtii QU 25 plasmid pQY039, complete sequence	7093-7122	8	0.733
NC_022196_1	1.7\|945417\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945417-945446	30	NC_022883	Enterococcus mundtii QU 25 plasmid pQY082, complete sequence	18573-18602	8	0.733
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	NZ_CP043762	Paenibacillus sp. 37 plasmid pART37, complete sequence	125059-125088	8	0.733
NC_022196_1	1.10\|945615\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945615-945644	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	729868-729897	8	0.733
NC_022196_1	1.11\|945681\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945681-945710	30	NZ_CP013115	Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence	16699-16728	8	0.733
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	NZ_CP013150	Lactobacillus plantarum strain MF1298 plasmid pMF1298-1, complete sequence	9657-9686	8	0.733
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	NZ_CP028227	Lactobacillus plantarum strain SRCM101187 plasmid unnamed1, complete sequence	4624-4653	8	0.733
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	CP033373	Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence	59306-59335	8	0.733
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	NZ_CP032747	Lactobacillus paraplantarum strain DSM 10667 plasmid unnamed3, complete sequence	34383-34412	8	0.733
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	NZ_CP017364	Lactobacillus plantarum strain TMW 1.277 plasmid pL1277-1, complete sequence	29200-29229	8	0.733
NC_022196_1	1.13\|945813\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945813-945842	30	NZ_CP013151	Lactobacillus plantarum strain MF1298 plasmid pMF1298-2, complete sequence	32262-32291	8	0.733
NC_022196_1	1.14\|945879\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945879-945908	30	MN582103	Podoviridae sp. cty5g4, complete genome	43935-43964	8	0.733
NC_022196_1	1.17\|946077\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	946077-946106	30	NC_013930	Thioalkalivibrio sp. K90mix plasmid pTK9001, complete sequence	139374-139403	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	918112-918141	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	CAJCJZ010000002	Enterococcus phage vB_EfaS_140 genome assembly, contig: phage140-genome, whole genome shotgun sequence	58926-58955	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MT119361	Enterococus phage vipetofem, complete genome	60227-60256	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	NZ_CP046625	Streptococcus sp. CNU G3 plasmid p1_CUN_G3, complete sequence	36384-36413	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MK448750	Streptococcus phage Javan393, complete genome	33875-33904	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	LT615366	Enterococcus phage VPE25 genome assembly, chromosome: VPE25	25052-25081	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	LT546029	Enterococcus phage VFW genome assembly, chromosome: VFW	24984-25013	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	LT546030	Enterococcus phage VPE25 genome assembly, chromosome: I	25052-25081	8	0.733
NC_022196_1	1.19\|946209\|30\|NC_022196\|CRISPRCasFinder,CRT	946209-946238	30	MT119360	Enterococcus phage nattely, complete genome	25160-25189	8	0.733
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	227262-227295	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	112639-112672	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	MT080583	UNVERIFIED: Staphylococcus phage vB_SauM_EW13, complete genome	8346-8379	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	MT080586	UNVERIFIED: Staphylococcus phage vB_SauM_EW2, complete genome	128831-128864	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	MT080594	UNVERIFIED: Staphylococcus phage vB_SauM_EW4, complete genome	42994-43027	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	MT080582	UNVERIFIED: Staphylococcus phage vB_SauM_EW1, complete genome	60897-60930	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP009595	Bacillus cereus strain 3a plasmid pBFC_3, complete sequence	4155-4188	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP009606	Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence	182868-182901	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	177611-177644	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP030782	Escherichia albertii strain 07-3866 plasmid unnamed, complete sequence	61042-61075	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP031075	Bacillus mycoides strain BPN401 plasmid pl37, complete sequence	26751-26784	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP053994	Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence	256639-256672	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP043834	Bacillus sp. BS98 plasmid unnamed4	42401-42434	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP021876	Enterococcus wangshanyuanii strain MN05 plasmid unnamed3	159973-160006	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP009691	Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence	288294-288327	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	CP002509	Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence	71463-71496	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP020436	Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence	2218-2251	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP053992	Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence	239655-239688	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP045267	Bacillus megaterium strain FDU301 plasmid pFDU301E, complete sequence	26516-26549	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	246931-246964	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_AP017915	Candidatus Azobacteroides pseudotrichonymphae plasmid pAPPJ1 DNA, complete sequence, phylotype ProJPt-1	13259-13292	8	0.765
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP024376	Borrelia miyamotoi strain Izh-14 plasmid pIzh14-lp26, complete sequence	29053-29086	8	0.765
NC_022196_1	1.1\|945021\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945021-945050	30	NZ_CP040337	Bacillus luti strain FJ plasmid unnamed1, complete sequence	18374-18403	9	0.7
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP020429	Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence	47928-47957	9	0.7
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP015284	Streptococcus salivarius strain ATCC 25975 plasmid, complete sequence	49304-49333	9	0.7
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	56461-56490	9	0.7
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	MN480763	Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence	70495-70524	9	0.7
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP020430	Streptococcus sp. FDAARGOS_192 plasmid unnamed2 sequence	5556-5585	9	0.7
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	NZ_CP020430	Streptococcus sp. FDAARGOS_192 plasmid unnamed2 sequence	14953-14982	9	0.7
NC_022196_1	1.5\|945285\|30\|NC_022196\|PILER-CR,CRISPRCasFinder,CRT	945285-945314	30	AP014166	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S46-C82, * SEQUENCING IN PROGRESS *	24341-24370	9	0.7
NC_022196_1	1.14\|945879\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945879-945908	30	AB797215	Klebsiella phage 0507-KN2-1 DNA, complete genome	60195-60224	9	0.7
NC_022196_1	1.14\|945879\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945879-945908	30	MG428990	Klebsiella phage Menlow, complete genome	153316-153345	9	0.7
NC_022196_1	1.14\|945879\|30\|NC_022196\|CRISPRCasFinder,CRT,PILER-CR	945879-945908	30	MN045230	Klebsiella phage Magnus, complete genome	153758-153787	9	0.7
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_011783	Borreliella burgdorferi ZS7 plasmid ZS7_lp25, complete sequence	17774-17807	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_001850	Borreliella burgdorferi B31 plasmid lp25, complete sequence	17738-17771	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP039048	Piscirickettsia salmonis strain Psal-073 plasmid unnamed2, complete sequence	46137-46170	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP038900	Piscirickettsia salmonis strain Psal-006b plasmid unnamed2, complete sequence	43723-43756	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	KC595513	Bacillus phage Shanette, complete genome	106594-106627	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	KF554508	Bacillus phage CP-51, complete genome	73501-73534	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP036355	Bacillus sp. SYJ plasmid unnamed1, complete sequence	165846-165879	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP019601	Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence	28020-28053	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_012226	Brachyspira hyodysenteriae WA1 plasmid pBHWA1, complete sequence	9871-9904	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP026954	Staphylococcus aureus strain FDAARGOS_48 plasmid unnamed1	1783-1816	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP013040	Clostridium perfringens strain JP838 plasmid pJFP838C, complete sequence	32239-32272	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_007391	Spiroplasma citri pSci5 plasmid	25561-25594	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	LC383633	Staphylococcus aureus SI1 plasmid pWSI1 DNA, complete sequence	10301-10334	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP033050	Virgibacillus halodenitrificans strain Bac324 plasmid unnamed, complete sequence	244382-244415	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_015712	Clostridium perfringens plasmid pCPPB-1, complete sequence	31612-31645	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_010077	Staphylococcus aureus plasmid EDINA, complete sequence	10283-10316	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP029650	Staphylococcus aureus strain AR_0471 plasmid unnamed1, complete sequence	12985-13018	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_018952	Staphylococcus aureus plasmid pWBG747, complete sequence	14938-14971	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP014063	Staphylococcus aureus strain FDAARGOS_159 plasmid unnamed, complete sequence	28548-28581	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_013326	Staphylococcus aureus plasmid pWBG746, complete sequence	29785-29818	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_013348	Staphylococcus aureus plasmid pSK156, complete sequence	3413-3446	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP046370	Spiroplasma citri strain BR12 plasmid pScpBR12-2, complete sequence	34957-34990	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP023513	Enterococcus sp. FDAARGOS_375 plasmid unnamed2, complete sequence	7111-7144	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP047441	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-4, complete sequence	33136-33169	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_016942	Staphylococcus argenteus MSHR1132 plasmid pST75 complete sequence	4233-4266	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP053311	Spiroplasma citri strain C5 plasmid pScpC5-7, complete sequence	2192-2225	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP042473	Spiroplasma citri strain CC-2 plasmid pScpCC2-1, complete sequence	23095-23128	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	473246-473279	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_AP020312	Staphylococcus aureus strain KUH140013 plasmid p01KUH140013, complete sequence	10223-10256	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_022589	Providencia rettgeri strain 09ACRGNY2001 plasmid pPrY2001, complete sequence	42298-42331	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_AP014922	Staphylococcus aureus strain JH4899 plasmid pJSA01, complete sequence	10306-10339	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_017345	Staphylococcus aureus subsp. aureus TCH60 plasmid unnamed, complete sequence	6016-6049	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP013848	Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence	32692-32725	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP016589	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence	253459-253492	9	0.735
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	140443-140476	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_017235	Borreliella afzelii PKo plasmid lp28-7, complete sequence	5381-5414	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	MN693868	Marine virus AFVG_250M1130, complete genome	32194-32227	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP032824	Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence	61286-61319	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP024336	Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-lp41, complete sequence	41829-41862	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP045275	Bacillus megaterium strain FDU301 plasmid pFDU301C, complete sequence	31473-31506	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP053838	Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence	130667-130700	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP015440	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence	19978-20011	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP039267	Lactobacillus crispatus strain DC21.1 plasmid pLcDC21.1_1, complete sequence	7819-7852	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_LR134418	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9	16900-16933	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_MK715471	Arcobacter cryaerophilus strain M830MA plasmid pM830MA, complete sequence	9341-9374	10	0.706
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_022874	Bacillus thuringiensis YBT-1518 plasmid pBMB0229, complete sequence	35617-35650	11	0.676
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NZ_CP050184	Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence	192698-192731	11	0.676
NC_022196_2	2.1\|1488046\|34\|NC_022196\|CRISPRCasFinder	1488046-1488079	34	NC_018878	Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence	473221-473254	11	0.676

1. spacer 1.9|945549|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MK554696 (Fusobacterium phage Fnu1, complete genome) position: , mismatch: 1, identity: 0.967

gtgtaccttttgatttaagatacagttatt	CRISPR spacer
gtgtaccttttgatttaagatatagttatt	Protospacer
**********************.*******

2. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MN276049 (Acinetobacter phage BS46, complete genome) position: , mismatch: 3, identity: 0.88

agttaatcaaaagaaatgctattca	CRISPR spacer
tgttcaacaaaagaaatgctattca	Protospacer
 *** * ******************

3. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MN694566 (Marine virus AFVG_250M779, complete genome) position: , mismatch: 3, identity: 0.88

agttaatcaaaagaaatgctattca	CRISPR spacer
aattaaacaaaagaaatgctattga	Protospacer
*.**** **************** *

4. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN013077 (Klebsiella phage vB_KaeM_KaOmega, complete genome) position: , mismatch: 4, identity: 0.867

tttttcttttctcgtaaacaataa-aattca	CRISPR spacer
tttttcttttttcgtaaacgataatgattc-	Protospacer
**********.********.**** .****

5. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN693456 (Marine virus AFVG_25M411, complete genome) position: , mismatch: 4, identity: 0.867

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
aatgtttttttaaatcatcatatctttttt	Protospacer
  ******.*****************.***

6. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MH333064 (Klebsiella phage Mineola, complete genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

7. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MN434095 (Klebsiella pneumoniae phage JIPh_Kp122, complete genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

8. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MN101229 (Klebsiella phage KPN5, complete genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

9. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MG751100 (Klebsiella phage KP1, complete genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

10. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to NC_028686 (Klebsiella phage JD18, complete genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

11. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MK421971 (Klebsiella phage vB_KpnM_GF, partial genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

12. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to LR877331 (Klebsiella phage vB_KpnM_311F genome assembly, chromosome: 1) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

13. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MN101226 (Klebsiella phage KPN2 HKu-2019, complete genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

14. spacer 3.1|1816354|25|NC_022196|CRISPRCasFinder matches to MN101225 (Klebsiella phage KPN1, complete genome) position: , mismatch: 4, identity: 0.84

agttaatcaaaagaaatgctattca	CRISPR spacer
ggttcatcaatagaaatgctattcg	Protospacer
.*** ***** *************.

15. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN693441 (Marine virus AFVG_25M481, complete genome) position: , mismatch: 5, identity: 0.833

tttttcttttctcgtaaacaataaaattca--	CRISPR spacer
attttctattcttgtaaacaat--aattcagg	Protospacer
 ****** ****.*********  ******

16. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP045225 (Clostridioides difficile strain TW11 plasmid p_TW11, complete sequence) position: , mismatch: 5, identity: 0.853

ttttaataaaaaaaataaaaataaaagtgtttaa-	CRISPR spacer
attttataaaaaaaataaaattaaaa-tatttaat	Protospacer
 *** *************** ***** *.*****

17. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP047287 (Proteus cibarius strain G11 plasmid p52, complete sequence) position: , mismatch: 5, identity: 0.853

ttttaataaaaaaaataaaaataaaagtgtttaa--	CRISPR spacer
ttttaagaaaaaaaagaaaaat--aagtttttaaaa	Protospacer
****** ******** ******  **** *****

18. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP053373 (Proteus cibarius strain G32 plasmid pG32-51, complete sequence) position: , mismatch: 5, identity: 0.853

ttttaataaaaaaaataaaaataaaagtgtttaa--	CRISPR spacer
ttttaagaaaaaaaagaaaaat--aagtttttaaaa	Protospacer
****** ******** ******  **** *****

19. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP047341 (Proteus cibarius strain ZF1 plasmid pZF1-cfr, complete sequence) position: , mismatch: 5, identity: 0.853

ttttaataaaaaaaataaaaataaaagtgtttaa--	CRISPR spacer
ttttaagaaaaaaaagaaaaat--aagtttttaaaa	Protospacer
****** ******** ******  **** *****

20. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP045009 (Proteus cibarius strain ZF2 plasmid pZF2-cfr, complete sequence) position: , mismatch: 5, identity: 0.853

ttttaataaaaaaaataaaaataaaagtgtttaa--	CRISPR spacer
ttttaagaaaaaaaagaaaaat--aagtttttaaaa	Protospacer
****** ******** ******  **** *****

21. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 6, identity: 0.8

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
tttttctttactcctaaacaataaataata	Protospacer
********* *** ***********   .*

22. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 6, identity: 0.8

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
ctaatgttttctcgtaaccactaaaattca	Protospacer
.*  * *********** ** *********

23. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

24. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

25. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

26. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

27. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

28. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

29. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

30. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acttacttcttgaatcatcatatcttcttt	Protospacer
 .*  .*****.******************

31. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN693180 (Marine virus AFVG_25M318, complete genome) position: , mismatch: 6, identity: 0.8

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
aatgtttttttaaatcatcatatcgctttt	Protospacer
  ******.*************** ..***

32. spacer 1.8|945483|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_031931 (Flavobacterium phage Fpv2, complete genome) position: , mismatch: 6, identity: 0.8

aaaaaagaagtaaattacagaggtcaaaaa	CRISPR spacer
tttgaagaagtaaaaaacagaggtcaaaaa	Protospacer
   .**********  **************

33. spacer 1.8|945483|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to KU599877 (Flavobacterium phage Fpv1, complete genome) position: , mismatch: 6, identity: 0.8

aaaaaagaagtaaattacagaggtcaaaaa	CRISPR spacer
tttgaagaagtaaaaaacagaggtcaaaaa	Protospacer
   .**********  **************

34. spacer 1.8|945483|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053689 (Arthrobacter citreus strain NEB 577 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

aaaaaagaagtaaattacagaggtcaaaaa	CRISPR spacer
aaggcaaaagtaaattaaaaaggtcaaaaa	Protospacer
**.. *.********** *.**********

35. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP017994 (Planktothrix agardhii NIES-204 plasmid plasmid3 DNA, complete sequence) position: , mismatch: 6, identity: 0.8

tcaagagattgaatattagaagaa--cattgg	CRISPR spacer
ccaagagcttaaatattagaagaaataatt--	Protospacer
.****** **.*************   ***

36. spacer 1.16|946011|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NC_011311 (Aliivibrio salmonicida LFI1238 plasmid pVSAL840, complete sequence) position: , mismatch: 6, identity: 0.8

ccagtaatcatattcagagcctactatttg	CRISPR spacer
ttgataatcatattcagatccaactatttg	Protospacer
....************** ** ********

37. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 6, identity: 0.8

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gtaattgaatttgaaagaattgagaaaagt	Protospacer
* *************** ***.****   *

38. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 6, identity: 0.8

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gtaattgaatttgaaagaattgagaaaagt	Protospacer
* *************** ***.****   *

39. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MK284528 (Bacillus phage DK3, complete genome) position: , mismatch: 6, identity: 0.8

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
tatattgaatctgaaagtcttaagaatgtt	Protospacer
 * *******.******* ******** .*

40. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MK284526 (Bacillus phage DK1, complete genome) position: , mismatch: 6, identity: 0.8

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
tatattgaatctgaaagtcttaagaatgtt	Protospacer
 * *******.******* ******** .*

41. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP007647 (Lactobacillus salivarius strain JCM1046 plasmid pMP1046A, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaa-gtgtttaa	CRISPR spacer
ttttagtaaaaaaaacaaaaataaaaggtaggta-	Protospacer
*****.*********.********** **.  **

42. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP020859 (Lactobacillus salivarius strain ZLS006 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaa-gtgtttaa	CRISPR spacer
ttttagtaaaaaaaacaaaaataaaaggtaggta-	Protospacer
*****.*********.********** **.  **

43. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_007930 (Lactobacillus salivarius UCC118 plasmid pMP118, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaa-gtgtttaa	CRISPR spacer
ttttagtaaaaaaaacaaaaataaaaggtaggta-	Protospacer
*****.*********.********** **.  **

44. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP017108 (Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaa-gtgtttaa	CRISPR spacer
ttttagtaaaaaaaacaaaaataaaaggtaggta-	Protospacer
*****.*********.********** **.  **

45. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_003042 (Clostridium perfringens str. 13 plasmid pCP13, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaagaaaaaaaattaaaataaaaggcattac	Protospacer
****** ********* **********   ***

46. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_LT604075 (Lactobacillus salivarius isolate LPM01 plasmid II) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaa-gtgtttaa	CRISPR spacer
ttttagtaaaaaaaacaaaaataaaaggtaggta-	Protospacer
*****.*********.********** **.  **

47. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to CP002037 (Lactobacillus salivarius CECT 5713 plasmid pHN3, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaa-gtgtttaa	CRISPR spacer
ttttagtaaaaaaaacaaaaataaaaggtaggta-	Protospacer
*****.*********.********** **.  **

48. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_022551 (Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataa---aagtgtttaa	CRISPR spacer
ttttcataaaaaaaataaaaataatataaatgat---	Protospacer
**** *******************   **.** *

49. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_021183 (Clostridium pasteurianum BC1 plasmid pCLOPA01, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaata-aaagtgtttaa	CRISPR spacer
aatttataaaaaaaataaaaatagaaagtaatta-	Protospacer
  ** ****************** *****. ***

50. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_AP014865 (Bacillus thuringiensis serovar tolworthi strain Pasteur Institute Standard strain plasmid pKK1, complete sequence) position: , mismatch: 6, identity: 0.824

ttttaataaaaaaaataaaaataaaagtgtttaa-	CRISPR spacer
cttttataaagaaaataaaaat-aaagtattcaag	Protospacer
.*** *****.*********** *****.**.**

51. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043636 (Empedobacter brevis strain SE1-3 plasmid pSE1-3-20kb, complete sequence) position: , mismatch: 7, identity: 0.767

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
aaattcttttctcgtaaacactaaaatcat	Protospacer
   ***************** ******.

52. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043637 (Empedobacter brevis strain SE1-3 plasmid pSE1-3-14kb, complete sequence) position: , mismatch: 7, identity: 0.767

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
aaattcttttctcgtaaacactaaaatcat	Protospacer
   ***************** ******.

53. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050068 (Klebsiella aerogenes strain 035 plasmid p35, complete sequence) position: , mismatch: 7, identity: 0.767

-------tttttcttttctcgtaaacaataaaattca	CRISPR spacer
cgagaaatttttct-------taaacaataaaattca	Protospacer
       *******       ****************

54. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020848 (Klebsiella variicola strain KPN1481 plasmid pKPN1481-1, complete sequence) position: , mismatch: 7, identity: 0.767

-------tttttcttttctcgtaaacaataaaattca	CRISPR spacer
cgagaaatttttct-------taaacaataaaattca	Protospacer
       *******       ****************

55. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043927 (Klebsiella quasipneumoniae subsp. quasipneumoniae strain M17277 plasmid p17277A_477, complete sequence) position: , mismatch: 7, identity: 0.767

-------tttttcttttctcgtaaacaataaaattca	CRISPR spacer
cgagaaatttttct-------taaacaataaaattca	Protospacer
       *******       ****************

56. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021699 (Klebsiella pneumoniae strain AR_0158 plasmid tig00000727, complete sequence) position: , mismatch: 7, identity: 0.767

-------tttttcttttctcgtaaacaataaaattca	CRISPR spacer
cgagaaatttttct-------taaacaataaaattca	Protospacer
       *******       ****************

57. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015439 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence) position: , mismatch: 7, identity: 0.767

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
tttgtttttgtaaatcatcatatggtgtgg	Protospacer
********. *************  * *

58. spacer 1.6|945351|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN694695 (Marine virus AFVG_250M866, complete genome) position: , mismatch: 7, identity: 0.767

ctaaaaacttacaaaaaaatacattgaata	CRISPR spacer
aaaaaaatttacaaaaaaatagattagaaa	Protospacer
  *****.************* ***..* *

59. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041069 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_5, complete sequence) position: , mismatch: 7, identity: 0.767

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
tggtaaacccatttttctaaaatcttataa	Protospacer
 .. **   *********************

60. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032531 (Bacillus megaterium NCT-2 plasmid pNCT2_3, complete sequence) position: , mismatch: 7, identity: 0.767

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
tggtaaatccatttttctaaaatcttataa	Protospacer
 .. **   *********************

61. spacer 1.8|945483|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014049 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12A-MedDCM-OCT-S34-C33, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

aaaaaagaagtaaattacagaggtcaaaaa	CRISPR spacer
acttacgaactaaattacagaggtcaaatg	Protospacer
*   * *** ****************** .

62. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014045 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12-MedDCM-OCT-S26-C148, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaagagattgaatattagaagaacattgg	CRISPR spacer
gcaatagattgaacattagaagaaaaatta	Protospacer
 *** ********.********** * * .

63. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014054 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S33-C14, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaagagattgaatattagaagaacattgg	CRISPR spacer
gcaatagattgaacattagaagaaaaatta	Protospacer
 *** ********.********** * * .

64. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014053 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S29-C16, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaagagattgaatattagaagaacattgg	CRISPR spacer
gcaatagattgaacattagaagaaaaatta	Protospacer
 *** ********.********** * * .

65. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014060 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S45-C20, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaagagattgaatattagaagaacattgg	CRISPR spacer
gcaatagattgaacattagaagaaaaatta	Protospacer
 *** ********.********** * * .

66. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014055 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S41-C174, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaagagattgaatattagaagaacattgg	CRISPR spacer
gcaatagattgaacattagaagaaaaatta	Protospacer
 *** ********.********** * * .

67. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014052 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S27-C13, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaagagattgaatattagaagaacattgg	CRISPR spacer
gcaatagattgaacattagaagaaaaatta	Protospacer
 *** ********.********** * * .

68. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014058 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C12B-MedDCM-OCT-S42-C22, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaagagattgaatattagaagaacattgg	CRISPR spacer
gcaatagattgaacattagaagaaaaatta	Protospacer
 *** ********.********** * * .

69. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to MK448388 (Streptococcus satellite phage Javan259, complete genome) position: , mismatch: 7, identity: 0.767

aaataattgacctattaaaaactttatgtt	CRISPR spacer
caataactgaccaattaaaaactttagtca	Protospacer
 *****.***** *************  .

70. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR215032 (Mycoplasma gallopavonis strain NCTC10186 plasmid 2) position: , mismatch: 7, identity: 0.767

aaataattgacctattaaaaactt-tatgtt	CRISPR spacer
ctttaattgaccttttaaaaacttatacat-	Protospacer
   ********** ********** **..*

71. spacer 1.17|946077|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NC_019924 (Clostridium phage phi8074-B1, complete genome) position: , mismatch: 7, identity: 0.767

--tcattactccaagttgtccttgtctgttct	CRISPR spacer
atctataa--gcaagttgtccttgtctcttct	Protospacer
  ..** *   **************** ****

72. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to JX194239 (Staphylococcus phage SA11, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

73. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MT080584 (UNVERIFIED: Staphylococcus phage vB_SauM_EW15, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

74. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MT080590 (UNVERIFIED: Staphylococcus phage vB_SauM_EW27, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

75. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to KY779848 (Staphylococcus phage qdsa001, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

76. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to KX532239 (Staphylococcus phage StAP1, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

77. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to LC492751 (Staphylococcus phage KSAP7 genomic DNA, compelete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

78. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to LC492752 (Staphylococcus phage KSAP11 genomic DNA, compelete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

79. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MT080587 (UNVERIFIED: Staphylococcus phage vB_SauM_EW20, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

80. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to AP019522 (Staphylococcal phage MR003 DNA, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

81. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NC_022090 (Staphylococcus phage vB_SauM_Remus, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

82. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to KP881332 (Staphylococcus phage Stau2, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

83. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MT080588 (UNVERIFIED: Staphylococcus phage vB_SauM_EW22, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

84. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MT080595 (UNVERIFIED: Staphylococcus phage vB_SauM_EW41, partial genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

85. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NC_020877 (Staphylococcus phage vB_SauM_Romulus, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
acaattgaatttgaacctattaagaatgta	Protospacer
. *************  ********** .

86. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MK721199 (Enterococcus phage vB_EfaS_Ef5.1, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
ggttttaaatttgaaagtattgagaattaa	Protospacer
*.  **.**************.******

87. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MK721200 (Enterococcus phage vB_EfaS_Ef5.3, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
ggttttaaatttgaaagtattgagaattaa	Protospacer
*.  **.**************.******

88. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MH814918 (Acinetobacter phage AJO2 DNA polymerase (AJO2_38) gene, partial cds) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaaattgaaaatattaaagcgtcc	Protospacer
********* ******.******..  **.

89. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
ggaattgaaattgaaagaattaagagataa	Protospacer
*.******* ******* *******. *

90. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NZ_CP014351 (Borrelia hermsii HS1 isolate Browne Mountain plasmid cp28, complete sequence) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaagttgaatttcaaagtattaaatttgat	Protospacer
***.******** **********.  *  *

91. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MK448753 (Streptococcus phage Javan407, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaactattttggatgaa	Protospacer
**************** ****  *.**

92. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to KJ473423 (Acinetobacter phage vB_AbaP_Acibel007, complete genome) position: , mismatch: 7, identity: 0.767

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaaattgaaaatattaaagcgtcc	Protospacer
********* ******.******..  **.

93. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to CP037991 (Bacillus mycoides strain TH26 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaaaaaaaaaaaaaaaaaataaaa	Protospacer
*************** ***** ****. .*  **

94. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to KP027447 (Staphylococcus phage phiIPLA-C1C, complete genome) position: , mismatch: 7, identity: 0.794

ttttaataaaaaaaataaaaataaaagtgtttaa---	CRISPR spacer
ttttaagaaaaaaaataaa---aaaaatttgtaaaac	Protospacer
****** ************   ****.* * ***

95. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_015919 (Borreliella bissettii DN127 plasmid lp54, complete sequence) position: , mismatch: 7, identity: 0.794

ttttaataaaaaaaataaaaataaaagt--gtttaa	CRISPR spacer
ttataataaaaaaaataataataaatattgattt--	Protospacer
** *************** ****** .*  .***

96. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to MN694663 (Marine virus AFVG_250M439, complete genome) position: , mismatch: 7, identity: 0.794

ttttaataaaaaaaataaaaataaaagtgtttaa-----	CRISPR spacer
tttaaataaaaaaaataaaagtaaa-----ttaaaagtg	Protospacer
*** ****************.****     ****

97. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to MN694663 (Marine virus AFVG_250M439, complete genome) position: , mismatch: 7, identity: 0.794

ttttaataaaaaaaataaaaataaaagtgtttaa-----	CRISPR spacer
tttaaataaaaaaaataaaagtaaa-----ttaaaagtg	Protospacer
*** ****************.****     ****

98. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP020426 (Clostridioides difficile strain FDAARGOS_267 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.794

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttattaaaaaaaatataaataatattaattta	Protospacer
***** *********** ****** * *. ** *

99. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038624 (Arsenophonus nasoniae strain FIN plasmid pArsFIN12, complete sequence) position: , mismatch: 8, identity: 0.733

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
gatttcttttctccaaaacaataaactcgc	Protospacer
  ***********  ********** *.

100. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to KY979109 (Salmonella phage SHP1, complete genome) position: , mismatch: 8, identity: 0.733

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
tagtaggtttctcgtaaacagtaaaatttc	Protospacer
*  *   *************.*******.

101. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_019500 (Enterobacteria phage Bp7, complete genome) position: , mismatch: 8, identity: 0.733

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
tagtaggtttctcgtaaacagtaaaatttt	Protospacer
*  *   *************.*******.

102. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to KX171213 (Staphylococcus phage vB_SscM-2, complete genome) position: , mismatch: 8, identity: 0.733

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
tttgatttcttaaatcatcataaccctcaa	Protospacer
**** ***************** *....

103. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_047767 (Staphylococcus phage vB_SscM-1, complete genome) position: , mismatch: 8, identity: 0.733

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
tttgatttcttaaatcatcataaccctcaa	Protospacer
**** ***************** *....

104. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017574 (Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence) position: , mismatch: 8, identity: 0.733

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
ttttttctcttaaatcatcatataactagt	Protospacer
*** **.****************  ..  *

105. spacer 1.6|945351|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041068 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_4, complete sequence) position: , mismatch: 8, identity: 0.733

ctaaaaacttacaaaaaaatacattgaata	CRISPR spacer
aaaataatttacaaaaaaatacattaatgt	Protospacer
  ** **.*****************.*

106. spacer 1.6|945351|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to CP041516 (Bacillus aryabhattai strain KNU10 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

ctaaaaacttacaaaaaaatacattgaata	CRISPR spacer
aaaataatttacaaaaaaatacattaatgt	Protospacer
  ** **.*****************.*

107. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP017563 (Pseudanabaena sp. ABRG5-3 plasmid ABRG53c, complete sequence) position: , mismatch: 8, identity: 0.733

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
tttgaatagtatttttctagaatcttattt	Protospacer
   .*****.*********.********

108. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KP342511 (Enterococcus faecium isolate N12-493 plasmid pEfm12493, complete sequence) position: , mismatch: 8, identity: 0.733

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
aaaaactaggatttttctaaaataattagc	Protospacer
***** *** *************  *  .

109. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_014031 (Bacillus megaterium QM B1551 plasmid pBM600, complete sequence) position: , mismatch: 8, identity: 0.733

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
tggtaaatccatttttctaaaaccttataa	Protospacer
 .. **   *************.*******

110. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN657074 (Psychrobacter sp. strain ANT_P37 plasmid pA37P2, complete sequence) position: , mismatch: 8, identity: 0.733

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
ccaaaataggatttatctaaaatctaaggg	Protospacer
  ******* **** ********** * ..

111. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_022880 (Enterococcus mundtii QU 25 plasmid pQY039, complete sequence) position: , mismatch: 8, identity: 0.733

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
aaaaactaggatttttctaaaataattagc	Protospacer
***** *** *************  *  .

112. spacer 1.7|945417|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NC_022883 (Enterococcus mundtii QU 25 plasmid pQY082, complete sequence) position: , mismatch: 8, identity: 0.733

aaaaaatagcatttttctaaaatcttataa	CRISPR spacer
aaaaactaggatttttctaaaataattagc	Protospacer
***** *** *************  *  .

113. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043762 (Paenibacillus sp. 37 plasmid pART37, complete sequence) position: , mismatch: 8, identity: 0.733

tcaagagattgaatattagaagaacattgg	CRISPR spacer
tggtgagattgaatattggaagaatatatt	Protospacer
* . *************.******.**

114. spacer 1.10|945615|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 8, identity: 0.733

tcaagagattgaatattagaagaacattgg	CRISPR spacer
atagtggaatgaatattagaaaaacattgt	Protospacer
 .*. .** ************.*******

115. spacer 1.11|945681|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013115 (Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence) position: , mismatch: 8, identity: 0.733

agaaattcttagcacatcttaaatcaatgg	CRISPR spacer
attttttattagcacgtcttaaatcaattc	Protospacer
*    ** *******.************

116. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013150 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-1, complete sequence) position: , mismatch: 8, identity: 0.733

aaataattgacctattaaaaactttatgtt	CRISPR spacer
aaataaatgacctattaaaaaaatatggaa	Protospacer
****** **************  *   *

117. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028227 (Lactobacillus plantarum strain SRCM101187 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aaataattgacctattaaaaactttatgtt	CRISPR spacer
aaataaatgacctattaaaaaaatatggaa	Protospacer
****** **************  *   *

118. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to CP033373 (Lactobacillus fermentum strain DR9 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aaataattgacctattaaaaactttatgtt	CRISPR spacer
aaataaatgacctattaaaaaagtatggaa	Protospacer
****** **************  *   *

119. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032747 (Lactobacillus paraplantarum strain DSM 10667 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

aaataattgacctattaaaaactttatgtt	CRISPR spacer
aaataaatgacctattaaaaaaatatggaa	Protospacer
****** **************  *   *

120. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017364 (Lactobacillus plantarum strain TMW 1.277 plasmid pL1277-1, complete sequence) position: , mismatch: 8, identity: 0.733

aaataattgacctattaaaaactttatgtt	CRISPR spacer
aaataaatgacctattaaaaaaatatggaa	Protospacer
****** **************  *   *

121. spacer 1.13|945813|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013151 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-2, complete sequence) position: , mismatch: 8, identity: 0.733

aaataattgacctattaaaaactttatgtt	CRISPR spacer
aaataaatgacctattaaaaaaatatggaa	Protospacer
****** **************  *   *

122. spacer 1.14|945879|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to MN582103 (Podoviridae sp. cty5g4, complete genome) position: , mismatch: 8, identity: 0.733

atagaagttgtaaaacatagagcaagagat	CRISPR spacer
ggagaagttgtaaaaccttgagcaagcaca	Protospacer
. ************** * ******* .

123. spacer 1.17|946077|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to NC_013930 (Thioalkalivibrio sp. K90mix plasmid pTK9001, complete sequence) position: , mismatch: 8, identity: 0.733

tcattactccaagttgtccttgtctgttct	CRISPR spacer
aggttactccaagttgtcattgtctctatc	Protospacer
  .*************** ****** * ..

124. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
ccaattgaatttgaaagtcttaatgtagct	Protospacer
  **************** **** .   **

125. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to CAJCJZ010000002 (Enterococcus phage vB_EfaS_140 genome assembly, contig: phage140-genome, whole genome shotgun sequence) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaagtgttgatacaatg	Protospacer
******************.**.* *   .

126. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MT119361 (Enterococus phage vipetofem, complete genome) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaagtgttgatacaatg	Protospacer
******************.**.* *   .

127. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to NZ_CP046625 (Streptococcus sp. CNU G3 plasmid p1_CUN_G3, complete sequence) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
ctttgtgtatttgaaattattaagaatttt	Protospacer
     ** ******** ***********.*

128. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MK448750 (Streptococcus phage Javan393, complete genome) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaactattttagataaa	Protospacer
**************** ****  ..**

129. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to LT615366 (Enterococcus phage VPE25 genome assembly, chromosome: VPE25) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaagtgttgatacaatg	Protospacer
******************.**.* *   .

130. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to LT546029 (Enterococcus phage VFW genome assembly, chromosome: VFW) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaagtgttgatacaatg	Protospacer
******************.**.* *   .

131. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to LT546030 (Enterococcus phage VPE25 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaagtgttgatacaatg	Protospacer
******************.**.* *   .

132. spacer 1.19|946209|30|NC_022196|CRISPRCasFinder,CRT matches to MT119360 (Enterococcus phage nattely, complete genome) position: , mismatch: 8, identity: 0.733

gaaattgaatttgaaagtattaagaattct	CRISPR spacer
gaaattgaatttgaaagtgttgatacaatg	Protospacer
******************.**.* *   .

133. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaaaataagagtaaaagagagatg	Protospacer
******************.*.****** *    .

134. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataagaaaaataaatataattattcttca	Protospacer
*********.********* ****  .* .** *

135. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to MT080583 (UNVERIFIED: Staphylococcus phage vB_SauM_EW13, complete genome) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
atttaataaaaaaaataaaactaaattagagaaa	Protospacer
 ******************* ****   *   **

136. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to MT080586 (UNVERIFIED: Staphylococcus phage vB_SauM_EW2, complete genome) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
atttaataaaaaaaataaaactaaattagagaaa	Protospacer
 ******************* ****   *   **

137. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to MT080594 (UNVERIFIED: Staphylococcus phage vB_SauM_EW4, complete genome) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
atttaataaaaaaaataaaactaaattagagaaa	Protospacer
 ******************* ****   *   **

138. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to MT080582 (UNVERIFIED: Staphylococcus phage vB_SauM_EW1, complete genome) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
atttaataaaaaaaataaaactaaattagagaaa	Protospacer
 ******************* ****   *   **

139. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP009595 (Bacillus cereus strain 3a plasmid pBFC_3, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa-	CRISPR spacer
atttaataaaaaaattaaaattaaaa-cattaagg	Protospacer
 ************* ***** ***** ..** *.

140. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP009606 (Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa-	CRISPR spacer
atttaataaaaaaattaaaattaaaa-cattaagg	Protospacer
 ************* ***** ***** ..** *.

141. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa-	CRISPR spacer
atttaataaaaaaattaaaattaaaa-cattaagg	Protospacer
 ************* ***** ***** ..** *.

142. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP030782 (Escherichia albertii strain 07-3866 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
tgtcaataaaaaaaataaaaatataaatggatgt	Protospacer
* *.******************* **.**  *.

143. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP031075 (Bacillus mycoides strain BPN401 plasmid pl37, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaa---gtgtttaa	CRISPR spacer
ctttagtaaaaaaaattaaaataaaaaatgaatt---	Protospacer
.****.********** *********   * .**

144. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP053994 (Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa-	CRISPR spacer
atttaataaaaaaattaaaattaaaa-cattaagg	Protospacer
 ************* ***** ***** ..** *.

145. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP043834 (Bacillus sp. BS98 plasmid unnamed4) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaa---gtgtttaa	CRISPR spacer
ctttagtaaaaaaaattaaaataaaaaatgaatt---	Protospacer
.****.********** *********   * .**

146. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP021876 (Enterococcus wangshanyuanii strain MN05 plasmid unnamed3) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gcttcctaaaaaaaataaaaaaataagtgttgga	Protospacer
 .**  *************** * ******* .*

147. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP009691 (Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaaattaaaaattaagggaggaaa	Protospacer
************** ******* **.* .   **

148. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to CP002509 (Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa---	CRISPR spacer
atttaataaaaaaattaaaattaaaca---ttaaggg	Protospacer
 ************* ***** **** .   ****

149. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP020436 (Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaa---gtgtttaa	CRISPR spacer
ctttagtaaaaaaaattaaaataaaaaatgaatt---	Protospacer
.****.********** *********   * .**

150. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP053992 (Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa-	CRISPR spacer
atttaataaaaaaattaaaattaaaa-cattaagg	Protospacer
 ************* ***** ***** ..** *.

151. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP045267 (Bacillus megaterium strain FDU301 plasmid pFDU301E, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gtttaataaaaaagatataaataaacattttgat	Protospacer
 ************.*** ******* .* ** *

152. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP043831 (Bacillus sp. BS98 plasmid unnamed1) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa---	CRISPR spacer
atttaataaaaaaattaaaattaaaca---ttaaggg	Protospacer
 ************* ***** **** .   ****

153. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_AP017915 (Candidatus Azobacteroides pseudotrichonymphae plasmid pAPPJ1 DNA, complete sequence, phylotype ProJPt-1) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa---	CRISPR spacer
tttcaatacaaaaaataaaaataa---ttcctaatta	Protospacer
***.**** ***************   * ..***

154. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP024376 (Borrelia miyamotoi strain Izh-14 plasmid pIzh14-lp26, complete sequence) position: , mismatch: 8, identity: 0.765

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
tttttataaaaaaaacaaaaataatataataaaa	Protospacer
**** **********.******** *  .*  **

155. spacer 1.1|945021|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040337 (Bacillus luti strain FJ plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

tttttcttttctcgtaaacaataaaattca	CRISPR spacer
aacaggatttctcttaaacaatcaaattca	Protospacer
  .    ****** ******** *******

156. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020429 (Streptococcus sp. FDAARGOS_192 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acctagttctgaaatcatcatatcttctga	Protospacer
 ..   **** *****************

157. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015284 (Streptococcus salivarius strain ATCC 25975 plasmid, complete sequence) position: , mismatch: 9, identity: 0.7

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acctagttctgaaatcatcatatcttctga	Protospacer
 ..   **** *****************

158. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 9, identity: 0.7

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acctagttctgaaatcatcatatcttctga	Protospacer
 ..   **** *****************

159. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to MN480763 (Streptococcus salivarius strain YU10 plasmid pSsal-YU10, complete sequence) position: , mismatch: 9, identity: 0.7

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acctagttctgaaatcatcatatcttctga	Protospacer
 ..   **** *****************

160. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020430 (Streptococcus sp. FDAARGOS_192 plasmid unnamed2 sequence) position: , mismatch: 9, identity: 0.7

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acctagttctgaaatcatcatatcttctga	Protospacer
 ..   **** *****************

161. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020430 (Streptococcus sp. FDAARGOS_192 plasmid unnamed2 sequence) position: , mismatch: 9, identity: 0.7

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
acctagttctgaaatcatcatatcttctga	Protospacer
 ..   **** *****************

162. spacer 1.5|945285|30|NC_022196|PILER-CR,CRISPRCasFinder,CRT matches to AP014166 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S46-C82, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

tttgttttcttaaatcatcatatcttcttt	CRISPR spacer
cagcaattcttaaataatcatatcttgtta	Protospacer
.     ********* ********** **

163. spacer 1.14|945879|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to AB797215 (Klebsiella phage 0507-KN2-1 DNA, complete genome) position: , mismatch: 9, identity: 0.7

atagaagttgtaaaacatagagcaagagat	CRISPR spacer
ttagaagttgttaaacatagggcatccaca	Protospacer
 ********** ********.***   .

164. spacer 1.14|945879|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to MG428990 (Klebsiella phage Menlow, complete genome) position: , mismatch: 9, identity: 0.7

atagaagttgtaaaacatagagcaagagat	CRISPR spacer
ttagaagttgttaaacatagggcatccaca	Protospacer
 ********** ********.***   .

165. spacer 1.14|945879|30|NC_022196|CRISPRCasFinder,CRT,PILER-CR matches to MN045230 (Klebsiella phage Magnus, complete genome) position: , mismatch: 9, identity: 0.7

atagaagttgtaaaacatagagcaagagat	CRISPR spacer
ttagaagttgttaaacatagggcatccaca	Protospacer
 ********** ********.***   .

166. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_011783 (Borreliella burgdorferi ZS7 plasmid ZS7_lp25, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ctttattaataaaaataaaaataaaaataaaaat	Protospacer
.**** *** ****************.*.   *

167. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_001850 (Borreliella burgdorferi B31 plasmid lp25, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ctttattaataaaaataaaaataaaaataaaaat	Protospacer
.**** *** ****************.*.   *

168. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP039048 (Piscirickettsia salmonis strain Psal-073 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aatttataaaaaaaataaaaataaaaataaaaat	Protospacer
  ** *********************.*.   *

169. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP038900 (Piscirickettsia salmonis strain Psal-006b plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aatttataaaaaaaataaaaataaaaataaaaat	Protospacer
  ** *********************.*.   *

170. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to KC595513 (Bacillus phage Shanette, complete genome) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaagacaaaaataaaaagagtacc	Protospacer
*************.*.**********. . *

171. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to KF554508 (Bacillus phage CP-51, complete genome) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaagacaaaaataaaaagagtacc	Protospacer
*************.*.**********. . *

172. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP036355 (Bacillus sp. SYJ plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aaataataaaaaaaataacaataaatgttgttcg	Protospacer
   *************** ****** **  ** .

173. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP019601 (Brachyspira hyodysenteriae strain BH718 plasmid pBH718, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aattaataaaaaaaataaaaattatagaaataga	Protospacer
  ******************** * ** . * .*

174. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_012226 (Brachyspira hyodysenteriae WA1 plasmid pBHWA1, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aattaataaaaaaaataaaaattatagaaataga	Protospacer
  ******************** * ** . * .*

175. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP026954 (Staphylococcus aureus strain FDAARGOS_48 plasmid unnamed1) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

176. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP013040 (Clostridium perfringens strain JP838 plasmid pJFP838C, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gattaataaacaaaacaaaaataaaattataaat	Protospacer
  ******** ****.********** *.*  *

177. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_007391 (Spiroplasma citri pSci5 plasmid) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaacaaaaaaaatataaataatattttaagg	Protospacer
******.********** ****** * * *  ..

178. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to LC383633 (Staphylococcus aureus SI1 plasmid pWSI1 DNA, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

179. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP033050 (Virgibacillus halodenitrificans strain Bac324 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
tagacaaaaataaaataaaaataaaactgttata	Protospacer
*    * *** *************** ****  *

180. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_015712 (Clostridium perfringens plasmid pCPPB-1, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gattaataaacaaaacaaaaataaaattataaat	Protospacer
  ******** ****.********** *.*  *

181. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_010077 (Staphylococcus aureus plasmid EDINA, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

182. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP029650 (Staphylococcus aureus strain AR_0471 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

------ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aatgcctctt------aaaattcaaaataaaagtgtttaa	Protospacer
      *.**      **** * *****************

183. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_018952 (Staphylococcus aureus plasmid pWBG747, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

184. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP014063 (Staphylococcus aureus strain FDAARGOS_159 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

185. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_013326 (Staphylococcus aureus plasmid pWBG746, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

186. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_013348 (Staphylococcus aureus plasmid pSK156, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

187. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP046370 (Spiroplasma citri strain BR12 plasmid pScpBR12-2, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaacaaaaaaaatataaataatattttaagg	Protospacer
******.********** ****** * * *  ..

188. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP023513 (Enterococcus sp. FDAARGOS_375 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
tgctataaaaaaaaataaaaataaacttgttatt	Protospacer
* .**  ******************  ****

189. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP047441 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-4, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaacaaaaaaaatataaataatattttaagg	Protospacer
******.********** ****** * * *  ..

190. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_016942 (Staphylococcus argenteus MSHR1132 plasmid pST75 complete sequence) position: , mismatch: 9, identity: 0.735

------ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aatgcctctt------aaaattcaaaataaaagtgtttaa	Protospacer
      *.**      **** * *****************

191. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP053311 (Spiroplasma citri strain C5 plasmid pScpC5-7, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaacaaaaaaaatataaataatattttaagg	Protospacer
******.********** ****** * * *  ..

192. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP042473 (Spiroplasma citri strain CC-2 plasmid pScpCC2-1, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaacaaaaaaaatataaataatattttaagg	Protospacer
******.********** ****** * * *  ..

193. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa-----	CRISPR spacer
ttttgataaaaaaaatacaaataagaa-----aaaaatc	Protospacer
****.************ ******.*.     **

194. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_AP020312 (Staphylococcus aureus strain KUH140013 plasmid p01KUH140013, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

195. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_022589 (Providencia rettgeri strain 09ACRGNY2001 plasmid pPrY2001, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
tgttaattaaaaaaagaaaaataaaaacattccg	Protospacer
* ***** ******* **********...**. .

196. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_AP014922 (Staphylococcus aureus strain JH4899 plasmid pJSA01, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaatatagaaataataacggccat	Protospacer
************* ***.****** *..* ..*

197. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_017345 (Staphylococcus aureus subsp. aureus TCH60 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

------ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aatgcctctt------aaaattcaaaataaaagtgtttaa	Protospacer
      *.**      **** * *****************

198. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP013848 (Clostridium botulinum strain Af650 plasmid pRSJ14_1, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaag--tgtttaa	CRISPR spacer
atttaataaaaaacatgaaaataaagaacagttc--	Protospacer
 ************ **.********..   ***.

199. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP016589 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-01, complete sequence) position: , mismatch: 9, identity: 0.735

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ggttaataaagaaaataaaattaaaattacaaaa	Protospacer
  ********.********* ***** *..  **

200. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
taacaataaaattaataaaaataaaagtatagtt	Protospacer
*  .*******  ***************.*

201. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_017235 (Borreliella afzelii PKo plasmid lp28-7, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
attaaataataaaaataaaaataaaaataaactt	Protospacer
 ** ***** ****************.*.  .

202. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to MN693868 (Marine virus AFVG_250M1130, complete genome) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaaagagaaaaataaagaacaaaca	Protospacer
*************.* *********..      *

203. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP032824 (Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaagaaataaaaagaagaagagaaga	Protospacer
***********.********* **.*. .   .*

204. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP024336 (Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-lp41, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gattaaaaaaaaaaaaaaaaataaaaagatgcga	Protospacer
  **** ******** **********. .* ..*

205. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP045275 (Bacillus megaterium strain FDU301 plasmid pFDU301C, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaaagaataaaaacaacctcattctc	Protospacer
************.********.**   ..**.

206. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP053838 (Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaagaaataaaaagaagaagagaaga	Protospacer
***********.********* **.*. .   .*

207. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP015440 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gctagaagaaaaaaagaaaaataaaagtgatttt	Protospacer
 .* .* .******* ************* **

208. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP039267 (Lactobacillus crispatus strain DC21.1 plasmid pLcDC21.1_1, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gattaaataaaaaaataaaaataaaaaaatcttt	Protospacer
  ****  ******************. .*.*

209. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_LR134418 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
tatttataaaaaaaataaatataaaaacccggag	Protospacer
* ** ************** ******.. .  *.

210. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_MK715471 (Arcobacter cryaerophilus strain M830MA plasmid pM830MA, complete sequence) position: , mismatch: 10, identity: 0.706

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
ttttaataaaagaaataaaaagaagaagagaaga	Protospacer
***********.********* **.*. .   .*

211. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_022874 (Bacillus thuringiensis YBT-1518 plasmid pBMB0229, complete sequence) position: , mismatch: 11, identity: 0.676

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
gtttaataaaagaaataaaaatgaaaagaaaggt	Protospacer
 **********.**********.***. .   .

212. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NZ_CP050184 (Bacillus thuringiensis strain HER1410 plasmid pLUSID1, complete sequence) position: , mismatch: 11, identity: 0.676

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
aattaagaaaaaatataaaaataaaagctccgcc	Protospacer
  **** ****** *************. ..

213. spacer 2.1|1488046|34|NC_022196|CRISPRCasFinder matches to NC_018878 (Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence) position: , mismatch: 11, identity: 0.676

ttttaataaaaaaaataaaaataaaagtgtttaa	CRISPR spacer
cattaaaaataaaaataaaaataaaaataaaatg	Protospacer
. **** ** ****************.*.    .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1202797 : 1209782

Prochlorococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008799442.1\|1202797_1204312_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	5.6e-61	44.5
WP_005890423.1\|1204349_1205159_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_008799443.1\|1205219_1205777_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	3.3e-19	35.2
WP_008799444.1\|1205764_1206784_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SQF5	Cyanophage	2.5e-65	43.8
WP_008799445.1\|1206983_1208333_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	8.5e-53	32.0
WP_008799446.1\|1208366_1209080_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	1.9e-43	43.2
WP_008799447.1\|1209308_1209782_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.1e-27	49.7

DBSCAN-SWA_2

1583558 : 1601061

Fusobacterium_phage(61.9%)

integrase

attL 1588056:1588071|attR 1599518:1599533

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020975264.1\|1583558_1583783_+	hypothetical protein	A0A0E3Y5H4	Fusobacterium_phage	2.0e-07	61.9
WP_008799680.1\|1583798_1584032_+	hypothetical protein	NA	NA	NA	NA
WP_020975265.1\|1584063_1584273_+	hypothetical protein	M1NRR1	Streptococcus_phage	3.8e-05	47.8
WP_008799682.1\|1584269_1584449_-	hypothetical protein	A0A0E3U2R0	Fusobacterium_phage	3.4e-18	85.5
WP_008799683.1\|1584448_1584802_-	hypothetical protein	NA	NA	NA	NA
WP_020975266.1\|1584806_1585310_-	hypothetical protein	A0A0E3Y4W5	Fusobacterium_phage	1.2e-49	65.3
WP_008799685.1\|1585503_1586304_-	ATP-binding protein	A6XMI1	Bacillus_virus	1.9e-07	27.4
WP_008799686.1\|1586305_1587046_-	conserved phage C-terminal domain-containing protein	A0A0H4IPD8	Staphylococcus_phage	1.2e-32	41.4
WP_147386706.1\|1588005_1588278_-	hypothetical protein	NA	NA	NA	NA
1588056:1588071	attL	NA	NA	NA	NA
WP_008799688.1\|1588521_1588743_-	hypothetical protein	NA	NA	NA	NA
WP_008799689.1\|1588900_1589299_-	hypothetical protein	NA	NA	NA	NA
WP_008799690.1\|1589309_1589489_-	hypothetical protein	NA	NA	NA	NA
WP_008799691.1\|1589488_1589686_-	hypothetical protein	NA	NA	NA	NA
WP_008799692.1\|1589704_1590361_-	helix-turn-helix transcriptional regulator	A0A0E3U270	Fusobacterium_phage	4.0e-48	50.5
WP_008799693.1\|1590523_1590898_+	hypothetical protein	A0A0E3Y6I8	Fusobacterium_phage	1.1e-47	73.6
WP_020975268.1\|1590907_1591138_+	hypothetical protein	A0A0E3Y5I4	Fusobacterium_phage	2.5e-21	64.0
WP_020975269.1\|1591185_1591407_+	hypothetical protein	A0A0E3U243	Fusobacterium_phage	2.0e-12	52.1
WP_008799694.1\|1591637_1592330_+	hypothetical protein	A0A0E3Y6D2	Fusobacterium_phage	6.8e-123	97.4
WP_008799695.1\|1592339_1592852_+	siphovirus Gp157 family protein	A0A0E3U2R8	Fusobacterium_phage	3.2e-69	83.3
WP_041461279.1\|1592997_1593585_+	hypothetical protein	A0A0E3Y6J2	Fusobacterium_phage	2.9e-106	95.4
WP_008799697.1\|1593581_1593881_+	hypothetical protein	NA	NA	NA	NA
WP_008799698.1\|1593877_1594108_+	hypothetical protein	A0A2H4JCC5	uncultured_Caudovirales_phage	6.1e-12	50.0
WP_008799699.1\|1594070_1594535_+	HNH endonuclease	M1PKJ5	Streptococcus_phage	2.1e-19	42.1
WP_020975273.1\|1594527_1595097_+	hypothetical protein	NA	NA	NA	NA
WP_008799701.1\|1595083_1595236_+	hypothetical protein	A0A0E3Y654	Fusobacterium_phage	1.9e-14	91.3
WP_020975274.1\|1595235_1595631_+	hypothetical protein	NA	NA	NA	NA
WP_008799702.1\|1595732_1595888_+	hypothetical protein	NA	NA	NA	NA
WP_008799703.1\|1595902_1596133_+	hypothetical protein	NA	NA	NA	NA
WP_020975275.1\|1596119_1596509_+	hypothetical protein	A0A191ZDH8	Pseudoalteromonas_virus	2.7e-12	36.8
WP_008799705.1\|1596513_1597044_+	dUTP diphosphatase	A0A0E3U2S3	Fusobacterium_phage	2.7e-47	55.7
WP_008799706.1\|1597057_1597249_+	hypothetical protein	NA	NA	NA	NA
WP_008799707.1\|1597286_1598354_+\|integrase	site-specific integrase	A0A0E3Y5J2	Fusobacterium_phage	1.4e-50	35.0
WP_005887816.1\|1599086_1600061_-	ATP-binding cassette domain-containing protein	Q6GZ03	Mycoplasma_phage	7.1e-09	33.0
1599518:1599533	attR	NA	NA	NA	NA
WP_005911776.1\|1600053_1601061_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.8e-19	31.6

DBSCAN-SWA_3

1774134 : 1830857

Clostridium_phage(31.58%)

tRNA,transposase,plate,integrase,holin,terminase,tail

attL 1781088:1781105|attR 1790493:1790510

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008799831.1\|1774134_1774851_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_008799832.1\|1774860_1775424_+	RNA methyltransferase	NA	NA	NA	NA
WP_008799833.1\|1775694_1780044_+	PolC-type DNA polymerase III	A0A0A8WJ41	Clostridium_phage	9.8e-26	35.1
WP_008799834.1\|1780055_1781339_+	serine protein kinase PrkA	NA	NA	NA	NA
1781088:1781105	attL	NA	NA	NA	NA
WP_008796925.1\|1781328_1782096_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_008799835.1\|1782240_1783599_+	dipeptidase PepV	NA	NA	NA	NA
WP_008796923.1\|1783611_1784481_+	DUF2156 domain-containing protein	NA	NA	NA	NA
WP_008796922.1\|1784489_1786109_+	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_020975298.1\|1786559_1786937_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_008799837.1\|1787017_1787953_+	WYL domain-containing protein	NA	NA	NA	NA
WP_008799838.1\|1788166_1789063_-	GTPase Era	NA	NA	NA	NA
WP_008799839.1\|1789066_1789825_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_008799840.1\|1789826_1791503_-	DNA repair protein RecN	NA	NA	NA	NA
1790493:1790510	attR	NA	NA	NA	NA
WP_008799841.1\|1791481_1792285_-	NAD(+)/NADH kinase	NA	NA	NA	NA
WP_020975300.1\|1792302_1793532_-	murein hydrolase activator EnvC	NA	NA	NA	NA
WP_008799843.1\|1793506_1794439_-	ABC transporter permease	NA	NA	NA	NA
WP_008796914.1\|1794589_1794979_-	adhesion protein FadA	NA	NA	NA	NA
WP_008796913.1\|1795081_1795765_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_005891555.1\|1796086_1798318_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	3.9e-172	42.1
WP_005913717.1\|1798379_1799111_+	pyruvate formate lyase-activating protein	A0A2P0VNQ0	Tetraselmis_virus	6.9e-25	30.0
WP_005891551.1\|1799183_1799897_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.7e-18	28.4
WP_008799845.1\|1799896_1800679_-	ABC transporter ATP-binding protein	A0A1M7XV31	Cedratvirus	9.1e-15	24.8
WP_008799846.1\|1800668_1801643_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_008799847.1\|1801643_1802531_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_008796909.1\|1802544_1803699_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008796908.1\|1803908_1804691_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_008799848.1\|1804710_1807149_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_008799849.1\|1807513_1809253_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.0e-31	26.8
WP_008799850.1\|1809264_1811064_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.4e-49	29.8
WP_005913285.1\|1811131_1811389_-	50S ribosomal protein L28	NA	NA	NA	NA
WP_020975303.1\|1813260_1813719_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	1.2e-14	34.4
WP_008799853.1\|1814408_1816280_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_020789258.1\|1816492_1816927_+	hypothetical protein	NA	NA	NA	NA
WP_020789257.1\|1816990_1818529_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	3.0e-30	38.7
WP_020975305.1\|1818662_1819049_-\|holin	phage holin family protein	A0A0E3Y658	Fusobacterium_phage	1.9e-42	76.3
WP_008799857.1\|1819060_1819510_-	DUF1353 domain-containing protein	A0A1B2ICK0	Erwinia_phage	1.2e-11	42.6
WP_008799858.1\|1819496_1819880_-	hypothetical protein	NA	NA	NA	NA
WP_008799859.1\|1819894_1820092_-	hypothetical protein	NA	NA	NA	NA
WP_008799860.1\|1820151_1820661_-	M15 family metallopeptidase	A0A0E3Y6B0	Fusobacterium_phage	7.6e-39	51.7
WP_020975306.1\|1820774_1821497_-	hypothetical protein	A0A0E3U2P7	Fusobacterium_phage	4.7e-82	64.4
WP_008799863.1\|1822257_1822908_-	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_008799864.1\|1822900_1823965_-\|plate	baseplate J/gp47 family protein	A0A0A7RUN3	Clostridium_phage	1.1e-42	36.2
WP_008799865.1\|1823965_1824394_-	DUF2634 domain-containing protein	A0A0A7RUS1	Clostridium_phage	1.0e-20	41.5
WP_008799866.1\|1824395_1824848_-	DUF2577 family protein	NA	NA	NA	NA
WP_008799867.1\|1824844_1825888_-	hypothetical protein	A0A0A7RTP6	Clostridium_phage	4.0e-26	28.0
WP_008799868.1\|1825892_1826339_-	hypothetical protein	NA	NA	NA	NA
WP_008799869.1\|1826352_1828260_-\|tail	phage tail tape measure protein	H9A124	Staphylococcus_phage	8.3e-54	37.3
WP_008799870.1\|1828321_1828783_-	hypothetical protein	NA	NA	NA	NA
WP_008799871.1\|1828946_1829315_-	hypothetical protein	NA	NA	NA	NA
WP_008799872.1\|1829324_1829765_-\|tail	phage tail tube protein	A0A0K2SUB8	Clostridium_phage	2.8e-29	47.3
WP_008799873.1\|1829777_1830857_-\|terminase	terminase	A0A0A8WJL8	Clostridium_phage	1.6e-41	35.1

DBSCAN-SWA_4

1834576 : 1857447

Fusobacterium_phage(56.0%)

portal,integrase,terminase

attL 1830554:1830570|attR 1862640:1862656

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1830554:1830570	attL	NA	NA	NA	NA
WP_020975307.1\|1834576_1834789_-	hypothetical protein	E8ZDL3	Streptococcus_phage	2.1e-14	54.7
WP_008799883.1\|1836444_1837761_-\|portal	phage portal protein	A0A0M4S669	Bacillus_phage	2.8e-85	43.2
WP_020975308.1\|1837773_1838913_-\|terminase	phage terminase large subunit	A0A1X9I5Q1	Streptococcus_phage	2.5e-114	57.9
WP_020975309.1\|1838982_1839189_-	hypothetical protein	A0A090EUA8	Clostridium_phage	1.7e-13	58.7
WP_008799885.1\|1839199_1839592_-\|terminase	terminase small subunit	Q9AZ67	Lactococcus_phage	1.5e-10	36.4
WP_008799886.1\|1839656_1839917_-	hypothetical protein	NA	NA	NA	NA
WP_008799887.1\|1840258_1840759_-	sigma-70 region 4 domain-containing protein	NA	NA	NA	NA
WP_008799888.1\|1840770_1841127_-	hypothetical protein	NA	NA	NA	NA
WP_008799889.1\|1841128_1841866_-	phage antirepressor KilAC domain-containing protein	A0A2H4J9M3	uncultured_Caudovirales_phage	8.5e-39	46.1
WP_020975310.1\|1841870_1842332_-	hypothetical protein	A0A0E3Y4W5	Fusobacterium_phage	1.8e-42	56.9
WP_020975311.1\|1842341_1842515_-	hypothetical protein	NA	NA	NA	NA
WP_008799891.1\|1842525_1843740_-	DnaB-like helicase C-terminal domain-containing protein	A0A0E3Y6C3	Fusobacterium_phage	2.3e-206	94.8
WP_020975312.1\|1844934_1845072_+	hypothetical protein	NA	NA	NA	NA
WP_008799893.1\|1845178_1845451_-	hypothetical protein	NA	NA	NA	NA
WP_008799894.1\|1845648_1845864_-	hypothetical protein	NA	NA	NA	NA
WP_008799895.1\|1845983_1846469_-	PH domain-containing protein	A0A0E3U2R5	Fusobacterium_phage	6.8e-61	76.4
WP_008799896.1\|1846600_1846765_-	hypothetical protein	NA	NA	NA	NA
WP_008799897.1\|1846832_1847684_-	hypothetical protein	NA	NA	NA	NA
WP_008799898.1\|1847693_1848110_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_008799899.1\|1848122_1848542_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_008799900.1\|1848723_1849110_+	hypothetical protein	A0A0E3Y6I8	Fusobacterium_phage	5.2e-48	73.6
WP_020975313.1\|1849119_1849350_+	hypothetical protein	A0A0E3Y5I4	Fusobacterium_phage	1.6e-20	62.7
WP_020975314.1\|1849359_1849620_+	hypothetical protein	A0A0E3U243	Fusobacterium_phage	3.0e-15	51.2
WP_008799901.1\|1849848_1850541_+	hypothetical protein	A0A0E3Y6D2	Fusobacterium_phage	7.3e-125	97.4
WP_008799902.1\|1850550_1851063_+	siphovirus Gp157 family protein	A0A0E3U2R8	Fusobacterium_phage	2.7e-84	98.8
WP_008799903.1\|1851072_1851315_+	hypothetical protein	A0A0E3U272	Fusobacterium_phage	2.4e-06	44.6
WP_008799904.1\|1851326_1852049_+	hypothetical protein	A0A0E3Y6J2	Fusobacterium_phage	1.6e-106	95.9
WP_008799905.1\|1852045_1852324_+	hypothetical protein	NA	NA	NA	NA
WP_008799906.1\|1852448_1852886_+	DUF3310 domain-containing protein	Q7Y4J5	Streptococcus_phage	1.6e-13	53.4
WP_008799907.1\|1852888_1853041_+	hypothetical protein	A0A0E3Y654	Fusobacterium_phage	1.4e-09	73.9
WP_020975315.1\|1853057_1853567_+	hypothetical protein	A0A0E3U273	Fusobacterium_phage	1.8e-40	58.7
WP_020975316.1\|1853559_1854267_+	phosphoadenosine phosphosulfate reductase family protein	Q24LD4	Clostridium_phage	8.4e-28	39.5
WP_008799910.1\|1854331_1854742_+	hypothetical protein	B5SP14	Lactococcus_phage	4.9e-12	35.8
WP_008799911.1\|1854744_1855200_+	methyltransferase	A0A0E3Y6D6	Fusobacterium_phage	1.5e-81	90.7
WP_008799912.1\|1855206_1855497_+	hypothetical protein	A0A0E3T9M1	Staphylococcus_phage	1.1e-05	40.6
WP_008799913.1\|1855496_1856027_+	dUTP diphosphatase	A0A0E3U2S3	Fusobacterium_phage	1.4e-46	56.2
WP_008799915.1\|1856219_1856417_+	hypothetical protein	NA	NA	NA	NA
WP_020975317.1\|1856403_1857447_+\|integrase	site-specific integrase	A0A0A8WF08	Clostridium_phage	1.1e-95	50.6
1862640:1862656	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022196

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection