CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	3 crisprs	WYL,DEDDh,cas2,cas1,cas9,csa3	0	22	4
NC_014632	Ilyobacter polytropus DSM 2926, complete sequence	1 crisprs	csa3,DEDDh,DinG,cas3	1	0	5
NC_014634	Ilyobacter polytropus DSM 2926 plasmid pILYOP02, complete sequence	0 crisprs	PD-DExK	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_014633_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014633_1

271811-271951

Orphan

Consensus_repeat	Method
AACCCCCGACAAGGCCCTCAACCTTGCGCGTCTACCATTCCGCCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014633_1

>merge|NC_014633|1|271811-271951|CRISPRCasFinder
AACCCCCGACAAGGCCCTCAACCTTGCGCGTCTACCATTCCGCCACCTGCGCTTGTAAATGGTGCGTGAAGGGGGACTTGAACCCCCACCGGGAAACCCCCGACAAGGCCCTCAACCTTGCGCGTCTACCATTCCGCCACC

>NC_014633|1|1|271811-271951|CRISPRCasFinder
AACCCCCGACAAGGCCCTCAACCTTGCGCGTCTACCATTCCGCCACC	TGCGCTTGTAAATGGTGCGTGAAGGGGGACTTGAACCCCCACCGGGA
AACCCCCGACAAGGCCCTCAACCTTGCGCGTCTACCATTCCGCCACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014633.1\|WP_013388618.1\|266907_269571_+\|NTPase-(NACHT-family)	unknown	unknown	gnl\|CDD\|227922
NC_014633.1\|WP_013388621.1\|273412_274909_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NC_014633.1\|WP_013388625.1\|278101_278812_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|181800
NC_014633.1\|WP_013388619.1\|269677_271453_+\|hypothetical-protein	unknown	unknown	unknown
NC_014633.1\|WP_049774908.1\|260847_261693_+\|phosphate-ABC-transporter-permease-subunit-PstC	unknown	unknown	gnl\|CDD\|223646
NC_014633.1\|WP_013388629.1\|284524_286189_-\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|376511
NC_014633.1\|WP_013388620.1\|272026_273277_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NC_014633.1\|WP_013388626.1\|278859_279987_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NC_014633.1\|WP_013388616.1\|265085_266081_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377376
NC_014633.1\|WP_013388612.1\|261707_262553_+\|phosphate-ABC-transporter-permease-PstA	unknown	unknown	gnl\|CDD\|223654
NC_014633.1\|WP_013388615.1\|264133_264829_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_014633.1\|WP_013388624.1\|276704_278099_-\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235611
NC_014633.1\|WP_013388614.1\|263429_264107_+\|phosphate-uptake-regulator-PhoU	unknown	unknown	gnl\|CDD\|273990
NC_014633.1\|WP_013388627.1\|280005_280518_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|376377
NC_014633.1\|WP_049774894.1\|266218_266680_+\|phage-virion-morphogenesis-protein	unknown	unknown	gnl\|CDD\|227338
NC_014633.1\|WP_013388628.1\|280551_284277_-\|phosphoribosylformylglycinamidine-synthase	unknown	unknown	gnl\|CDD\|130916
NC_014633.1\|WP_013388622.1\|275130_275703_-\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|187714
NC_014633.1\|WP_013388623.1\|275690_276689_-\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NC_014633.1\|WP_013388613.1\|262614_263376_+\|phosphate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224042
NC_014633.1\|WP_013388610.1\|259807_260641_+\|phosphate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270371

Protein	Function_ID	Function_description	E-value
NC_014633.1\|WP_013388618.1\|266907_269571_+\|NTPase-(NACHT-family)	gnl\|CDD\|227922	COG5635, COG5635, Predicted NTPase (NACHT family) [Signal transduction mechanisms].	1.20173e-21
NC_014633.1\|WP_013388621.1\|273412_274909_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_014633.1\|WP_013388625.1\|278101_278812_-\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|181800	PRK09362, PRK09362, phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed.	2.27223e-139
NC_014633.1\|WP_049774908.1\|260847_261693_+\|phosphate-ABC-transporter-permease-subunit-PstC	gnl\|CDD\|223646	COG0573, PstC, ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism].	2.89567e-75
NC_014633.1\|WP_013388629.1\|284524_286189_-\|formate--tetrahydrofolate-ligase	gnl\|CDD\|376511	pfam01268, FTHFS, Formate--tetrahydrofolate ligase.	0
NC_014633.1\|WP_013388620.1\|272026_273277_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NC_014633.1\|WP_013388626.1\|278859_279987_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	3.95175e-168
NC_014633.1\|WP_013388616.1\|265085_266081_+\|hypothetical-protein	gnl\|CDD\|377376	pfam04519, Bactofilin, Polymer-forming cytoskeletal. This is a family of bactofilins, a functionally diverse class of cytoskeletal, polymer-forming, proteins that is widely conserved among bacteria. In the example species C. crescentus, two bactofilins assemble into a membrane-associated laminar structure that shows cell-cycle-dependent polar localization and acts as a platform for the recruitment of a cell wall biosynthetic enzyme involved in polar morphogenesis. Bactofilins display distinct subcellular distributions and dynamics in different bacterial species, suggesting that they are versatile structural elements that have adopted a range of different cellular functions.	0.00212348
NC_014633.1\|WP_013388612.1\|261707_262553_+\|phosphate-ABC-transporter-permease-PstA	gnl\|CDD\|223654	COG0581, PstA, ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism].	2.05016e-88
NC_014633.1\|WP_013388615.1\|264133_264829_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.49372e-71
NC_014633.1\|WP_013388624.1\|276704_278099_-\|amidophosphoribosyltransferase	gnl\|CDD\|235611	PRK05793, PRK05793, amidophosphoribosyltransferase; Provisional.	0
NC_014633.1\|WP_013388614.1\|263429_264107_+\|phosphate-uptake-regulator-PhoU	gnl\|CDD\|273990	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU. This model describes PhoU, a regulatory protein of unknown mechanism for high-affinity phosphate ABC transporter systems. The protein consists of two copies of the domain described by pfam01895. Deletion of PhoU activates constitutive expression of the phosphate ABC transporter and allows phosphate transport, but causes a growth defect and so likely has some second function. [Regulatory functions, Other, Transport and binding proteins, Anions].	2.96662e-23
NC_014633.1\|WP_013388627.1\|280005_280518_-\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	3.74182e-90
NC_014633.1\|WP_049774894.1\|266218_266680_+\|phage-virion-morphogenesis-protein	gnl\|CDD\|227338	COG5005, COG5005, Mu-like prophage protein gpG [General function prediction only].	1.94891e-19
NC_014633.1\|WP_013388628.1\|280551_284277_-\|phosphoribosylformylglycinamidine-synthase	gnl\|CDD\|130916	TIGR01857, FGAM-synthase, phosphoribosylformylglycinamidine synthase, clade II. This model represents a single-molecule form of phosphoribosylformylglycinamidine synthase, also called FGAM synthase, an enzyme of purine de novo biosynthesis. This model represents a second clade of these enzymes found in Clostridia, Bifidobacteria and Streptococcus species. This enzyme performs the fourth step in IMP biosynthesis (the precursor of all purines) from PRPP. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis].	0
NC_014633.1\|WP_013388622.1\|275130_275703_-\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|187714	cd08645, FMT_core_GART, Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART). Phosphoribosylglycinamide formyltransferase, also known as GAR transformylase or GART, is an essential enzyme that catalyzes the third step in de novo purine biosynthesis. This enzyme uses formyl tetrahydrofolate as a formyl group donor to produce 5'-phosphoribosyl-N-formylglycinamide. In prokaryotes, GART is a single domain protein but in most eukaryotes it is the C-terminal portion of a large multifunctional protein which also contains GAR synthetase and aminoimidazole ribonucleotide synthetase activities.	1.20891e-90
NC_014633.1\|WP_013388623.1\|275690_276689_-\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NC_014633.1\|WP_013388613.1\|262614_263376_+\|phosphate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224042	COG1117, PstB, ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism].	5.57242e-178
NC_014633.1\|WP_013388610.1\|259807_260641_+\|phosphate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.07176e-101

>NC_014633.1|WP_013388619.1|269677_271453_+|hypothetical-protein
MNNLEILKMLEEKFKPTIDVPHSVFIDGKWGIGKTEIIKQFQIKIKISKPYLKVYYISLFGKNTFKEIETEIINKVLFPKFSKAQNGGGAHLFKQFSKDVLKGIAKNKTGIELDIFSYMKSLSLENIAFGSDMIFIFDDLERLTNQIQLRVVLGSIEKVSLKSSVIIIGNYSEIGHIKKDSNPNENNNKPEKNLIQLEFDKFKEKIINREYKYLKNNNSVFNSIIEKYWDDETVSYFDKDYLISYFEKCGKSNLRTFIKILLLLKEIMPKLKEEPLFKNFQKEIIRVSSALIIEMYSGTNKIDMSCIEDSKKSNDLFKTFREINLKHDYGLFGTIDLLLMEILFEYLSKNKLNLQRFKTQVNPEKLEIQKDIDQLNTYFFYSDEQIEIIVNKIVEKIKETNIDYFIDQEKIVELIVHLEIVLNDMEWQDLYTELKENIPFISQIANELSIVSKNDLMSIIHRKSYIKEINLYFSNQLINQINLNNDKRDSEEKLNTFKNALTKKEYRKCYEALTVDSFNVGYIELLKSIKKEIIAPILDPEIDSNYWSLIHFLFPLIYEKDDILMDLDSNSIKKNSMINKRIEILKKQYNN
>NC_014633.1|WP_013388618.1|266907_269571_+|NTPase-(NACHT-family)
MELTAFSVTLASKLFDKAFDLGVTKLSKDSLNKKFKKAVSESIEKFKNMYPDVPIKSLQVFFFQEEIFNELQKILFKYSNINIQFIKQNLNVLSIPIEAVEKFIFILREELYKDIEFEEIFSNKELFVTILKLGHSIEEIKEYASLSYNELVKISSTLEKKYNENFDLDTFMDKYKTTVLTNIKQINYFGLGIDNNISKGRKNLDEIYIEPIFNLRKNNSLETCNITDLLNFKKNIVVLGNPGSGKSLFTKYIIYNFLKEGTYLKNTEFYKEIPIRVELKKYVSYKEKNRNIKNYILDLLKTTYGLENITEKNVEYFICNNYISLFFDGLDEIFDVNLREEIKKEIEIISINHPNLKIIVTSRIVGYDETIFNEEIFEKVEIIEFNNKQIRDYVKKWYDIEEKDDDIRKKEILEFFNQKKTIDITLLKNPLLLSLIVILFRNNGEIPESRLEIYRSCTKTLVHKWDENKKLKIDLDSKLLQKKENIFANLAYWQYKRLSNQGKHSDIKYIQVLREVSRIILELKITDDEIYADDLSDRFLEYSKNRSIYFENNFTHKTFLEYYAALWIHRYCAVKPSKQEELKDIFLNYALSSYWFIVLELLLNMMDEQQGDCEVLDDLLENIIDKNEKYLIFLLKVVPLIHNISDCLIKRIYFMALTQIIKEAYSSEDQNKNFFKLFNAIIESNLTPRCINILQTALDDLFPKLTSNQEKTNYHIFYYEFNQSLNDNLKIENKYIEDIQNHLDCNVLYIHTTHFIEGEINEQLCDKYIEKFGRKSMFEDFSFFYKHTTYFYPLIFRLLSNVFKNNFDYERLKRIFSKYEITKQEIGNRIHRTILLMTMGEEQLKKLKSEILEYKKIETDDALKHYIELAFKNIKGREEMFKLKRFG
>NC_014633.1|WP_049774894.1|266218_266680_+|phage-virion-morphogenesis-protein
MGNTSMDELIVKINNMEKKAKNLFPVMRKISIDMKNQTMKNFRQEKDPEGKPWKKNRRGGKTLTKTSRLKHSIRPAHGDNYAMVGTNVKYARIHQYGGKIKAKNGKYLKFQYAKGKWASRKSVIIPKRTFMGISRKMGDRYEVSIGEYTIKLK
>NC_014633.1|WP_013388616.1|265085_266081_+|hypothetical-protein
MKRVILIFIILFSTIYTMPVKGDRVDIRNPVDGNLISASERLTVNARVEKSIISASKFLDVNKSAKNIIAAASEINVLGDIDNILVSASRKLAVNGDVGGSIVVACESLLLNGNTGDVVVAAREVDVNGELDNLFVAADKIYISGTVRGNVYSTTNRVELIGDGEVLGEIYHQKEAPKIDRREIVKKSYGFIQIVSIVHSFLGIFVITFLLKKLAPDMEDKLSKNLFNKGLLAFFIGIFFLVTFPIFVIITMPIFGVYSFGIMLGYLLIIIFSKSFLVLAISKRYNYFLSIAVVVSLSFFYPFSLIFSIIGFGIFLIFVKDVLSRNPELEI
>NC_014633.1|WP_013388615.1|264133_264829_+|response-regulator-transcription-factor
MKVLIVEDDIEIQQLVGYFFKKDGYEVQFAGDGLDGLKFLKAFKPELVILDIMLPSLDGKNFTKIVRELPDQYGDPIIIMLTAKTEIEDVLEGLELGANDYMKKPFDPRELILRAKKLISGEMRESKRVSFAGVVVDDERHLVTENDVEVELSKKEYDLLHLLFNNKGIVLSREKILDRVWQTNYYSGDRSVDIYISKLRDKLKSISKNIRTVKGVGYKLEDRKEYSSKER
>NC_014633.1|WP_013388614.1|263429_264107_+|phosphate-uptake-regulator-PhoU
MKNLHERIESINNHFIEMAKNVERLLRINMEMLKNKSFEKVLYGEAKMVEDIVNSYEVKIKEDVVITIAMFQPAARDLRSLLSTLEGTKILERMGDLLLDNVQLIREMEKKGELHKPYLYLVEKVAEKVEEVYNIYTEALVGRDDTKVYTILALDEEVNEIRDDTVEKLIKVMKENPENIEFGNLILLSTKKYERISDKIMQLGKSLVYDISGDNLRKKELVKRD
>NC_014633.1|WP_013388613.1|262614_263376_+|phosphate-ABC-transporter-ATP-binding-protein
MENNIRLSVKNFNFYYGNFQALNNINMDVEKNKVTALIGPSGCGKSTFLRSINRMNDLIDISKYEGIIQLDETDIFDKKYDIVELRKSIGMVFQKPNPFPKTIYENIVYGPKLHGTRDKKKLDEIVEGSLKAVALWDEVKDKLHQSALGLSGGQQQRLCIARAIAVEPEILLMDEPTSALDPISTLKIERLIRDLAKDYTIIIVTHNMQQAARVSEYTGFFYQGVLEEFGPTEKIFTNPDNKKTEDYITGKFG
>NC_014633.1|WP_013388612.1|261707_262553_+|phosphate-ABC-transporter-permease-PstA
MSILKGNGKKIIETIIKVIGICSILPVLGIFAYIIFKGVPAITWSFITEGPKSGMREGGIFPVIVGSILLTIGTIIAAVPFGILTGIYLVEYSNDNWLRRIINLTIVNLAGIPSIVYGLFGMAFFVMALGMGRSLMAGSLTLGIMSLPVIITATRESLLAIPKSMREASLALGATRWETTWKIVLPAALPGILTGIILSVSRAAGETAPIMFTAAAFYLPFLPESLSDQVMALPYHLYVISTQVPNMPESNMMGTLFVLVFITVGFNLLGAYIRNKFRKFR
>NC_014633.1|WP_049774908.1|260847_261693_+|phosphate-ABC-transporter-permease-subunit-PstC
MKHTIFGVAAFNILIVFSIFFYVFTNGMKFFGEGSITDFLLGKTWIPLSDLYGFLPLLAGSFWVSIIALGISIPLSLFTAIYIAEYASKKTREVFKVLIETMAALPSVVLGYIGLYVFSKYIRDIFGLNSGLTALNGGVLLAIMAIPTMVSIADDAIMALDKSYKEASLAIGANKLETIVKVLLPAAFPGIFAGIMLGFGRIIGETMTVLMVTGNSPILNSGPLTAVRTLTATIAAEMGEVTIGDQHYYSLFTLGIVLFAISFLTNTVADHFIHKSRKNIG
>NC_014633.1|WP_013388610.1|259807_260641_+|phosphate-ABC-transporter-substrate-binding-protein
MLKKTLLGLSLLILVACGQDKVKSEVVQITGSDTCLNVTQQLSETYMESHEDARIAVTGGGSGVGIAAAINGTTDIAMASRNAKEKELKSAEDAGRLLEEVVFGWDGLSVITHPSNPVNVLSKEVIGKIFSGEIKNWKEIGGKDAKIILLSRDSSSGTHVYFKEDVVRGGDKKSNKEYADETLFLPSNTAIVQEAATNENSIGYVGMAYMDETVKAISVNGVEPTVENVASKQYPIARELFWYVPAERSQVISNIVEFVLSPEGQAIVADEGFVPAK
>NC_014633.1|WP_013388620.1|272026_273277_-|phosphoribosylamine--glycine-ligase
MKILVVGSGGREHAICWKIQENKNVNKIYCAPGNAGTELLEKVENVDLQGMEDILAFAEKEKIDLTMVGSEELLVAGIVDKFKEKGLKIFGPDSKAALLEGSKAYAKDFMKKYGVKTAAYEIFTDADKAKAYLDTINFPVVIKASGLAAGKGVLICADIKEGIEAVNDIMVDKKFSDAGNEVVIEEFLEGVEASILSITDSKQIVSFISAKDHKKIGEGDTGLNTGGMGVIAPNPYVTTEVYDHYIKDIVEPTLNGIKAEGLDFCGVIFFGLMINSRGVYLLEYNMRMGDPETQVVLPLLDSDFLDILNDTLQGTLDNDKIKWKDQSACCVVAASGGYPEAYNKGYEITGCETVEDIVFMAGVKKEDEKFVTSGGRVLNVVALGKDLDDAKKNAYNSIEKIKFDKMYYRRDIGKIN
>NC_014633.1|WP_013388621.1|273412_274909_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKRALISVYDKTGILDFAKFLVETGVEVVSTGGTYKYLRENSIPVTEVSEVTGAAEMLDGRVKTLHPNIHGGILAIRSNKEHMETLEKREIAPIDMVIVNLYPFFDEVQNDISFEEKVEFIDIGGPTMLRSAAKSFEDVIVITDVEDYSKIQKEIESTGNLSFENRKKLAGKVFNLTSAYDAAISNFLLEGEMPKYLSVSYEKMMDLRYGENPHQNAAYYVSTTEKGAMKDFEQLNGKELSFNNIRDMDVAWKVVSEFEETACCGLKHSTPCGVAVAETVAEAYKKSYDCDPISIFGGIVAVNTTVDGETAAEMSKTFLEIVIATDFTEEALEILKKKKNLRIIKAKYTPCDKIEYVKVDGGILVQDSDKAFSKDFKVVTEKDPSKKEMDDMVFGMKVVKHVKSNAIVVVKDGMAKGVGTGETNRIWAAKQAIERAGDGAVLASDAFFPFRDVVDECAKAGITAIVQPGGSMRDQESIDACNEHKISMVFTGLRHFKH
>NC_014633.1|WP_013388622.1|275130_275703_-|phosphoribosylglycinamide-formyltransferase
MLNIAVLVSGGGSNFQAIIDKINDGKLPCKIDCVIADRKCYGLERGSSNGIKTYLLDRKELKKNLSKEIDTILEGKVDLIVLAGFLSILDSEFTKKWSKKIINIHPSLLPKFGGPGMYGIKIHQAVIAAGEKESGCTVHYVDAGVDTGEIIYQEKVSVLENDTPETLQKKVLEIEHRLLPQAIMDIAEGN
>NC_014633.1|WP_013388623.1|275690_276689_-|phosphoribosylformylglycinamidine-cyclo-ligase
MSISYKDAGVNKEEGYKAVDLMKKAVSKTHNKCVLNGLGSFGAMYEMGQYKNPVLVSGTDGVGTKLEVAFKMGVYNTVGIDAVAMCVNDILCHGAKPMFFLDYMACGKLEAEKAAQLVSGVAEGCLQSGAALVGGETAEMPGFYKDGDYDIAGFSVGVVEKDEIINGSTVEDGDVIIALPSSGVHSNGFSLVRKLITDFDEELNGKKIGEVLLEPTKIYVKPILALLEKFTVKGMAHITGGGLPENLPRTIGEGYHPVVEKSKIKVLEIFKHLQSKGVPENEMYGTFNMGVGFVLVVAESDKDAVISELKTLGEEAYEIGYIKKGDKELCLI
>NC_014633.1|WP_013388624.1|276704_278099_-|amidophosphoribosyltransferase
MYDIHDIDKMEEECGVFGVYSKTAKEEISTLTYYGLYALQHRGQESAGITISNSGKKTTYKGMGLVADVFSSEKLKELQGNAAIGHVRYSTSGESKLVNAQPLESKFKLGQIAVAHNGTLVNADIIRELLEDSGSTFITNIDSEVIINMIARKASKGLEEAIRSTVSAIKGSYALTILADHKLIGVRDPYGIRPLCLGQNKEGDYFLASESCALDAAGADLIRDIEPGEMVVIDDDGVRSVKYAENTKNAPCSFETIYFARPDSIIDGKSAFQVRVESGKYLARQKPVDADVVIGVPDSGIPAAIGFAEESGIPYTVGLIKNKYIGRTFIKPSQELREKAVQVKLNPLKVNVEGKRVVVVDDSLVRGTTSRLLIQMLRRSGATEVHFRSASPAVKFPCYFGIDTAHRKELIAAKLSVEEIKEEIGADSLDYLTLPNLAKVLGSEDFCLGCFDGEYPVCTPMGEV
>NC_014633.1|WP_013388625.1|278101_278812_-|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MIKKDMVYEGKAKKVYSTEDPNLVIIHFKDDATAGNGAKKGTIENKGILNNKITATLYEILEKNGIKTHFKKMLNERDQLCEKVEIIPLEVIVRNVIAGSMAARVGIEEGTVPSNTIFEICYKNDKYNDPLINDHHAVAMGVTTYEDLAKIYDTTAKINNLLKETFDEEGITLVDFKIEFGKNKDGEILLADEITPDTCRLWDKETGEKLDKDRFRRDLGGIEEAYIEILKRLGAK
>NC_014633.1|WP_013388626.1|278859_279987_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MKKLGIIGGGQLGKMTILEARKMDIYTCVLTEEHPSPASEISNEYIIGSLHDEDKIREISEKCDVLTYEIEHINVEVLKELEAKGKKIFPSSRVIEIIQDKSKQKELLDEKNIPTSKWKKVTKDNLEELKKEFGFPVVQKSCKGGYDGRGVFILKDESDIEKMIQGDSFFEEFIECDKEIAVMVARNFNGDIATYPVVEMVFDDKTNICDTVVAPARITEDQCKEAKKLALQCVEALDGVGIFGVEMFLTKEGKILINEVAPRPHNSGHYTIEACKTSQYEQFIRAVLNYSLGNCDLLSPACMVNILGEDGYKGKVKVIGMDEMMSVDGAYLHLYGKKDTKPFRKMGHITVLSDSEEEACKLALKAREHLKIISE
>NC_014633.1|WP_013388627.1|280005_280518_-|5-(carboxyamino)imidazole-ribonucleotide-mutase
MGKIGIIMGSDSDLPVMSAAAKILDEFKIDYELTVVSAHRTVDKMYEYAKTADERGIDVIIAGAGGAAHLPGMVAAITSVPVIGVPVKSSNLSGLDSLLSIVQMPGGVPVATVAINGAKNAGILAAKIISIRDKAVKETVKKYMADMKEEVETKAEKVEELGYAKYLESM
>NC_014633.1|WP_013388628.1|280551_284277_-|phosphoribosylformylglycinamidine-synthase
MNYRIYVEKKDGFDVEAKGLLNELKEGFKLEKLQKVRILNSYDIFGITKEELEKAKRTIFSEVVMDQVYDTLDLKEEKYFAAEFLPGQFDQRADSAIQCLNLVSEKNQNVEVTSGKIIIFQGEITDEQLEKVKNFYINPVEMREKNLEKLHIESVEKPTEVPFIKGFTKFSEEEMEAYRSKEGFAMTLDDMMFVQSYFRNTENRDPSETEIKVLDTYWSDHCRHTTFETKIKEIVFPKGRFQKVLQETFDQYLESREFVHGEKIDKKHISLMDMATISGKELRKSGKLDDLEVSEEINACSVYVDVDVDGITEKWLLMFKNETHNHPTEIEPFGGASTCLGGAIRDPLSGRSYVYQAIRVTGSADPLEKLEDTMPGKLPQKKITKGAAHGYSAYGNQIGLTTGHVSEIYHSGYKAKRMEVGAVVGAVPADWVRRESSAPGDIVVLLGGKTGRDGCGGATGSSKEHTDESLATCGAEVQKGNAPEERKIQKLFRNPEVTKLIKKCNDFGAGGVSVAIGELADGLEIDLDVVPVKYEGLNGTELAISESQERMAVVIEEKDRDQFIDLADKENLLATVVATVTDRNRLEIFWKGNKIVDISRDFLDTNGVTQENNVELEAPAESSPLEQELFSEKEGKERWLKMLASLNVSSQKGLMEMFDSSIGASTVLMPFGGKYQMTPTDLSVQKFPLLKGETDTASAISWGYDPAVSSWSPFHGGAYAVVESLAKIVAAGGEWSKIRLSFQEYFQKLGKDPVNWGKPFSALLGTLFAQKQFEIAAIGGKDSMSGTFNEIHVPPTLISFAVSPVKASEVISPEFKKAGNKIYLIKHDMTADLMPNTKELKRNFNYMYENIKSGKIISAMTLKKGGVAEALAKMSFGNRVGVNIENLEENLFRLGYGSFVVEATEELSGKNIVFLGTTTEEENITVGDTVITLEEAEKTWLKTLEPVFPYETKEEKKDYIWTPYKAKEIIVAKNKIADPNVFIPAFPGTNCEYDAKKVFEKAGATTSGMTFKNLTQKHINESIEEMLKELNKSQILMIPGGFSSGDEPDGSGKFIATVLSNPKVADAIAKFLERDGLILGICNGFQALIKSGLLPYGEIGKVTEDSPTLTFNNIGRHISQMVSTKVTSNKSPWFSGIEVGTVHEIPVSHGEGRFYANEEVAIKLFENGQVATQYVDFEGKPSSEFKFNPNGSVYAIEGITSPDGKILGKMGHSERIGDNLYKNIIGDKEQKIFENGVKYFK
>NC_014633.1|WP_013388629.1|284524_286189_-|formate--tetrahydrofolate-ligase
MKSDIQIAQEAKLLKISEVAKTIGLSEDDYEQYGKYKAKVDPNLLRKLENKEDGKLVLVTAITPTPAGEGKSTVSVGLTQALNRLGKKSIAALREPSLGPVFGIKGGATGGGHSQVIPMEDINLHFTGDIHAIGVAHNLVSACIDNHLKFGNTLNIDITKITWKRVMDMNDRSLRNIVIGLGGTANGIPREDSFQITVASEIMAAMCLADSIADLKEKIGEMVFAYSTAGTPLKIKDLNVQGAVAALMKEAIKPNLVQTLENTPVFIHGGPFANIAHGCNSLLATKLALKLSDFAITEAGFAADLGAEKFLDIKCRKGGLTPNCVVVVATVRALKHHGGAKDLSVQDLDALQKGLSNLEKHIENMKKFNLPVVVAMNRFVTDTESEFDLIRKVCSDHNVPVADCDVWANGGAGGEELAKLVIGEIEKGEDNYTPLYSLESSPEEKIEIIAKEIYGADGVVFSPKAKKTIKTIVENGYGELPICVSKTQKSISDNPALLGRPENFTVTVNEIRLSAGAGFLVAMAGNIIDMPGLPKKPSAELIDIDENGKITGLF

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Crispr_ID: NC_014633_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014633_2

744582-745934

orTypeII

Consensus_repeat	Method
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CRISPRCasFinder
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CRT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	PILER-CR

20 spacers

cas2,cas1,cas9

The CRISPR arrays of NC_014633_2

>merge|NC_014633|2|744582-745934|CRISPRCasFinder,CRT,PILER-CR
CTCGTACTTCCCTAATTATTTTAGCTATGTTACAATAAGTTATACTTGAGTATAGAAAAAGCGGTGGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATATTCTAAATGTGATACCCTTAGTTTTATTTGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATGACTTGGAAGAGATTTTATCTGCAATAGGAGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATTTTGATTTATTAGAAACCTAAAGTGATTAGGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATAAGAGGGGAAAAACTAACCTCTCTTTTTGTGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATACTAGAAGAAAGTAAAGCTTGGATAGACTTGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATAAAATCTAAAAACTTAATACAGTTTGCAATGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATAGAGAGGATTACATAGTCAAAGATATAGGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATAGAAGAGAAAAGGCTTCAGACAGATAAAGCGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATGGTGGGGTTGTATATGACAGAGAGTTTATAGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATCCTGCCTGCATTTGGCTTTTGGCCTGCTTCGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATTCACTTTGTCTCAACTACTCCACATTTTCCGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATTAAAAATAACGCTACAAAGCTTACAGCCGGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATAAAGTGAATGTTATACACGCTGTCAAAGAGGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATCTAGAGGAGGTATAAATGTTCGGTGTAGGAGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATAAGTACCGCCTTACAGTATTCACAATATAAGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATATTATAATTTTTACTATCTACCTTTGATAAGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATGTATCAAGCGATATTACATATCAGCAAGGGGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATAAAATCGGATGGTTCATGGCATGTAGAAGGGTTGTACTTCCCTAATTATTTTAGCTATGTTACAATTCAAAAGAATTAGATTATACAATGGGTTATGTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT

>NC_014633|2|2|744582-745934|CRISPRCasFinder
CTCGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGTTATACTTGAGTATAGAAAAAGCGGTG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ATTCTAAATGTGATACCCTTAGTTTTATTT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GACTTGGAAGAGATTTTATCTGCAATAGGA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TTTGATTTATTAGAAACCTAAAGTGATTAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGAGGGGAAAAACTAACCTCTCTTTTTGT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ACTAGAAGAAAGTAAAGCTTGGATAGACTT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAATCTAAAAACTTAATACAGTTTGCAAT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AGAGAGGATTACATAGTCAAAGATATAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AGAAGAGAAAAGGCTTCAGACAGATAAAGC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GGTGGGGTTGTATATGACAGAGAGTTTATA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CCTGCCTGCATTTGGCTTTTGGCCTGCTTC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TCACTTTGTCTCAACTACTCCACATTTTCC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TAAAAATAACGCTACAAAGCTTACAGCCG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAGTGAATGTTATACACGCTGTCAAAGAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CTAGAGGAGGTATAAATGTTCGGTGTAGGA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGTACCGCCTTACAGTATTCACAATATAA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ATTATAATTTTTACTATCTACCTTTGATAA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GTATCAAGCGATATTACATATCAGCAAGGG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAATCGGATGGTTCATGGCATGTAGAAGG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TCAAAAGAATTAGATTATACAATGGGTTAT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT

>NC_014633|2|1|744582-745934|CRT
CTCGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGTTATACTTGAGTATAGAAAAAGCGGTG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ATTCTAAATGTGATACCCTTAGTTTTATTT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GACTTGGAAGAGATTTTATCTGCAATAGGA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TTTGATTTATTAGAAACCTAAAGTGATTAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGAGGGGAAAAACTAACCTCTCTTTTTGT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ACTAGAAGAAAGTAAAGCTTGGATAGACTT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAATCTAAAAACTTAATACAGTTTGCAAT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AGAGAGGATTACATAGTCAAAGATATAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AGAAGAGAAAAGGCTTCAGACAGATAAAGC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GGTGGGGTTGTATATGACAGAGAGTTTATA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CCTGCCTGCATTTGGCTTTTGGCCTGCTTC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TCACTTTGTCTCAACTACTCCACATTTTCC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TAAAAATAACGCTACAAAGCTTACAGCCG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAGTGAATGTTATACACGCTGTCAAAGAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CTAGAGGAGGTATAAATGTTCGGTGTAGGA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGTACCGCCTTACAGTATTCACAATATAA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ATTATAATTTTTACTATCTACCTTTGATAA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GTATCAAGCGATATTACATATCAGCAAGGG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAATCGGATGGTTCATGGCATGTAGAAGG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TCAAAAGAATTAGATTATACAATGGGTTAT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT

>NC_014633|2|1|744648-745934|PILER-CR
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ATTCTAAATGTGATACCCTTAGTTTTATTT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GACTTGGAAGAGATTTTATCTGCAATAGGA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TTTGATTTATTAGAAACCTAAAGTGATTAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGAGGGGAAAAACTAACCTCTCTTTTTGT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ACTAGAAGAAAGTAAAGCTTGGATAGACTT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAATCTAAAAACTTAATACAGTTTGCAAT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AGAGAGGATTACATAGTCAAAGATATAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AGAAGAGAAAAGGCTTCAGACAGATAAAGC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GGTGGGGTTGTATATGACAGAGAGTTTATA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CCTGCCTGCATTTGGCTTTTGGCCTGCTTC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TCACTTTGTCTCAACTACTCCACATTTTCC
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TAAAAATAACGCTACAAAGCTTACAGCCG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAGTGAATGTTATACACGCTGTCAAAGAG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	CTAGAGGAGGTATAAATGTTCGGTGTAGGA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAGTACCGCCTTACAGTATTCACAATATAA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	ATTATAATTTTTACTATCTACCTTTGATAA
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	GTATCAAGCGATATTACATATCAGCAAGGG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	AAAATCGGATGGTTCATGGCATGTAGAAGG
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT	TCAAAAGAATTAGATTATACAATGGGTTAT
GTTGTACTTCCCTAATTATTTTAGCTATGTTACAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_014633.1\|WP_013389018.1\|738743_739823_+\|tartrate-dehydrogenase	unknown	unknown	gnl\|CDD\|273963
NC_014633.1\|WP_013389031.1\|753931_754582_-\|HAD-hydrolase-like-protein	unknown	unknown	gnl\|CDD\|319798
NC_014633.1\|WP_013389022.1\|742623_743190_-\|elongation-factor-P	unknown	unknown	gnl\|CDD\|234788
NC_014633.1\|WP_013389025.1\|746346_747249_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NC_014633.1\|WP_041921399.1\|746033_746342_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_014633.1\|WP_013389026.1\|747262_750541_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NC_014633.1\|WP_013389023.1\|743308_744469_-\|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	unknown	unknown	gnl\|CDD\|378385
NC_014633.1\|WP_013389014.1\|732776_734120_-\|4-aminobutyrate--2-oxoglutarate-transaminase	unknown	unknown	gnl\|CDD\|223238
NC_014633.1\|WP_013389027.1\|750837_752196_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240548
NC_014633.1\|WP_013389019.1\|739885_740809_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_014633.1\|WP_148223746.1\|753421_753883_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|238032
NC_014633.1\|WP_013389017.1\|737745_738672_+\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NC_014633.1\|WP_013389015.1\|734204_735599_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129987
NC_014633.1\|WP_013389033.1\|755078_755963_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223687
NC_014633.1\|WP_013389021.1\|742155_742494_+\|hypothetical-protein	unknown	unknown	unknown
NC_014633.1\|WP_013389028.1\|752183_752636_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NC_014633.1\|WP_013389032.1\|754793_754988_-\|DUF4250-domain-containing-protein	unknown	unknown	gnl\|CDD\|379443
NC_014633.1\|WP_013389020.1\|740893_741676_-\|4,5-DOPA-dioxygenase-extradiol	unknown	unknown	gnl\|CDD\|153375
NC_014633.1\|WP_013389016.1\|736391_737564_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377939
NC_014633.1\|WP_013389029.1\|752841_753354_+\|ribonuclease-E-activity-regulator-RraA	unknown	unknown	gnl\|CDD\|236487

Protein	Function_ID	Function_description	E-value
NC_014633.1\|WP_013389018.1\|738743_739823_+\|tartrate-dehydrogenase	gnl\|CDD\|273963	TIGR02089, Probable_tartrate_dehydrogenase/decarboxylase, tartrate dehydrogenase. Tartrate dehydrogenase catalyzes the oxidation of both meso- and (+)-tartrate as well as a D-malate. These enzymes are closely related to the 3-isopropylmalate and isohomocitrate dehydrogenases found in TIGR00169 and TIGR02088, respectively. [Energy metabolism, Other].	3.70318e-176
NC_014633.1\|WP_013389031.1\|753931_754582_-\|HAD-hydrolase-like-protein	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.4614e-91
NC_014633.1\|WP_013389022.1\|742623_743190_-\|elongation-factor-P	gnl\|CDD\|234788	PRK00529, PRK00529, elongation factor P; Validated.	3.65159e-94
NC_014633.1\|WP_041921399.1\|746033_746342_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.9467e-35
NC_014633.1\|WP_013389025.1\|746346_747249_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	6.71515e-95
NC_014633.1\|WP_013389026.1\|747262_750541_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NC_014633.1\|WP_013389023.1\|743308_744469_-\|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	gnl\|CDD\|378385	pfam10093, EarP, Elongation-Factor P (EF-P) rhamnosyltransferase EarP. This entry includes family members such as EarP enzymes which are essential for post-translational activation of elongation factor P(EF-P). It was identified as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-beta-L-rhamnose as donor substrate. This was further confirmed for Pseudomonas aeruginosa, Pseudomonas putida, and Neisseria meningitidis. As for S. oneidensis and P. aeruginosa, EarP enzyme acts as an inverting glycosyltransferase, thus mediating the formation of an alpha-L-rhamnosidic linkage. Structural analysis show that EarP is composed of two opposing domains with Rossmann folds, thus constituting a B pattern-type glycosyltransferase (GT-B) and provide basis for arginine glycosylation by EarP. Mutational analysis of efp and earP genes, resulted in a substantial decrease in the production of rhamnolipids and pyocyanin (important factors for colonization and invasion during infection) of P. aeruginosa. Collectively this indicates that EarP and EF-P are essential for P. aeruginosa pathogenicity.The protein family is also annotated in the CaZy Database as GT104.	1.46666e-131
NC_014633.1\|WP_013389014.1\|732776_734120_-\|4-aminobutyrate--2-oxoglutarate-transaminase	gnl\|CDD\|223238	COG0160, GabT, 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism].	0
NC_014633.1\|WP_013389027.1\|750837_752196_-\|MATE-family-efflux-transporter	gnl\|CDD\|240548	cd13143, MATE_MepA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.	1.66015e-128
NC_014633.1\|WP_013389019.1\|739885_740809_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	5.24537e-20
NC_014633.1\|WP_148223746.1\|753421_753883_-\|HD-domain-containing-protein	gnl\|CDD\|238032	cd00077, HDc, Metal dependent phosphohydrolases with conserved 'HD' motif.	2.43749e-08
NC_014633.1\|WP_013389017.1\|737745_738672_+\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	8.05385e-31
NC_014633.1\|WP_013389015.1\|734204_735599_-\|amino-acid-permease	gnl\|CDD\|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.74197e-50
NC_014633.1\|WP_013389033.1\|755078_755963_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|223687	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism].	5.54569e-25
NC_014633.1\|WP_013389028.1\|752183_752636_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	2.50403e-15
NC_014633.1\|WP_013389032.1\|754793_754988_-\|DUF4250-domain-containing-protein	gnl\|CDD\|379443	pfam14056, DUF4250, Domain of unknown function (DUF4250). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There are two completely conserved residues (N and R) that may be functionally important.	1.85854e-23
NC_014633.1\|WP_013389020.1\|740893_741676_-\|4,5-DOPA-dioxygenase-extradiol	gnl\|CDD\|153375	cd07363, 45_DOPA_Dioxygenase, The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine. This subfamily is composed of plant 4,5-DOPA Dioxygenase, the uncharacterized Escherichia coli protein Jw3007, and similar proteins. 4,5-DOPA Dioxygenase catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine (4,5-DOPA). The reaction results in the opening of the cyclic ring between carbons 4 and 5 and producing an unstable seco-DOPA that rearranges to betalamic acid. 4,5-DOPA Dioxygenase is a key enzyme in the biosynthetic pathway of the plant pigment betalain. Homologs of DODA are present not only in betalain-producing plants but also in bacteria and archaea. This enzyme is a member of the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon.	4.17986e-109
NC_014633.1\|WP_013389016.1\|736391_737564_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	1.79053e-31
NC_014633.1\|WP_013389029.1\|752841_753354_+\|ribonuclease-E-activity-regulator-RraA	gnl\|CDD\|236487	PRK09372, PRK09372, ribonuclease E inhibitor RraA.	1.88762e-49

>NC_014633.1|WP_013389023.1|743308_744469_-|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP
MLKSIDIFCDIIDNFGDIGFVYRLAKEIKRKEKDARVRVFFNDAETFSKINKNIIVGEKIQIIEDITYYDMTIMSSEDYKKAGNSEVAIEAYGCDIPEVYLENSSEELKIVINIEYLTAEEWAKEYHLQSSYINVKGVKKYFYMPGFENWSGGLIIDNQVPVIDRVEFFNKVISSHSEKFFPVNSDLVVDKDTFVGTIFSYEYNFQNFLDTLENFDKKIILLIFGDMSKNGFLITKNIKALKNTKIIFMDYVEQNLYDEILNNSDFNFVRGEESFSRAIVSRVPFLWHAYCQEEKEHLNKVKGFLSFLKDKTPVDFYEKYSKITYNYNCRTENHYNLEEEDFSDFFENFEKEKKAFEYISDYVKKNGNLADKLLCFLKEKLSENDF
>NC_014633.1|WP_013389022.1|742623_743190_-|elongation-factor-P
MKTAQEISSGNIIKIGEEVFIIQKATYNKSGRNSAVVKFKMKNLITGQVKEDVMKAADKLEDIRLDKKTMQFLYEVGGDYNFMDQETFEQIALTADDLGDATNYLKEEMFIDILLYEERPVGVELPNSVEREVTYTEPGLRGDTTGKVLKPATIETGYELSVPLFVNIGDVIRIDTRNGEYLERVNNK
>NC_014633.1|WP_013389021.1|742155_742494_+|hypothetical-protein
MKNLNTMDTEVFYEYKELIMDTNHNVYDGAGSSENCEIIEEIYRFEPKTDAFEDMKNLIEDTNHNVYDGVSDSVLYCDAKEEIYRFEEPEVFQEIKDLIEDTNHYVYDGVAV
>NC_014633.1|WP_013389020.1|740893_741676_-|4,5-DOPA-dioxygenase-extradiol
MNRKQPVLFIGHGNPMNAISYNNFTKSLKKISETIEKPDAIVVISAHWQTKGTSITLSDDPKQIYDFYGFPRELYNVIYQPKGNEKLSNYIIETLNAEGAIVTGVDYWGLDHGSWGILIHIFPDGDIPVLQLSLDVDLDVDSHYQLGKKLSFLRDMGVLVIGSGNIVHNLKNIGKETLSEPYSWAVEFDRYIADSVSSDKHNNLIDYKNAGECAELSLPTDEHYLPLIYVAAMQTPGEKTEFFYDEIHHSSLSMRCLKIG
>NC_014633.1|WP_013389019.1|739885_740809_-|DMT-family-transporter
MNSKYIGYTMAFITIFVWGTTYAITKNLLNYFTPFEVLFLRFLIAYLFLLIVKPTFNFKFNFKFNFQEEKLFLLLGLTGGMLYFLVENMALKYTSASNVGLIVSSIPIFSSIIAHFTTEDEKFDKNLILGFALAITGIFLILYNGNKVLKINPIGDILAVVCSIIWAIYSNLLRKVDKSYSGLLVVRKTFFYGLMFMLPGLYLLKVKIHFEYLFNKDVSFSIFYLALVASSICFIMWSRSINIIGIIKTTNFIYLIPLVAMISSVVILDEKITPLMITGGLLILSGVLINDKKISFEKLFKPKTTTL
>NC_014633.1|WP_013389018.1|738743_739823_+|tartrate-dehydrogenase
MKKYKIAVIPGDGIGVEVMKEGVKVLETLSKLTGEVAFDFTWFDWGCEYYLENGKMMDDDGLEKLKNFDAILLGAVGFPGVPDHVSLRDLLLKIRQGFDQYINYRPVKLLSELDCPIKGKKPGDIDMIFIRENTEGEYAGIGGIEREGKEEEIALQTSVFTRKTTEKVMDYAFDLAKKRNKLNHLTSITKSNALNHSMVFWDKIFKEKKANYPEIKTAEYHVDAAAMYMIQRPESFDVVVASNLFGDILTDLGAALQGGLGFAAGANINPDGKYPSMFEPVHGSAPEIAGKGLANPIAMIWTIKIMLDFLGHESLADTVMKGIEGSLEMREKLTPDMGGKGSTSQVGEIICDIMSKKLN
>NC_014633.1|WP_013389017.1|737745_738672_+|AEC-family-transporter
MERIINSVTLIMFLMGTGCFFARKNILGEHSNKLFSYLVLNLCLPCLIILGLTSRFTREGLMQSTEWLGLSFVILLALILAAKIFSFSSFIKRKELFQLSFVFANTVFIGLPVNIALFGDESIPYIFLYYFANTCFFWTYGVYCVRGGGSIKDGFKKLMTPATISFFVGIIMILLDLKVPPFLATYMKYLGGMTTPLAMLYLGTAIYSLGIKSLKPDFEGLLDLISKFIIAPIIALVLIKIADGFLTLPVLLKKVYFIQTTMPIMTNVAILSGYYNKNPEDASKVVGLSTILVVVTIPVYAFLAEILF
>NC_014633.1|WP_013389016.1|736391_737564_+|PucR-family-transcriptional-regulator
MAMTLRELYESTNKRDIKLIAGKNGLDNVVRWAHMIEGKEISTYLEGQELSFVTGIALGKDESLFELVKHTYYNQASGMVINIGPYIEGISEEILQFCDENDFPLFQIPWHIYMANFIKDFCYQITISDRINIELLSAIKNAIFFPDQENLYKPQLEIHNFSANWPYCIAIIEILENSTGEIIGDEKRAKLLKNIENILIYSYKRTFIFELKGRFVLVFAEYSEDEIRNIVHEIKRKCREILKKKNKMYFCIGETSKNIDDISKSYHQAISILKLQKKRENSDEITAYSELGLYKLLLSMENKEAMSNYYQETLEPLAEYDKINGTDYMIVLDTYLKNNCSVKEVAAQLFYHRNSINYKLSKIQEILSCDLSQLNTRLVYSIALMLREII
>NC_014633.1|WP_013389015.1|734204_735599_-|amino-acid-permease
MTKQESFDRVLSKKDVLALAFGAMIGWGWVVMAGSWIETAGTLGAIIAFIMGGIMVLFVGLTYAELTSAMPKCGGEHVFSLRALGTNASFICTWAIILGYVSVVAFEAVAFPTVLEYLVPGYIQGKMYTVAGYDVYFTWVLVGMISSIAITVINYFGVKPAAFLQGVLTLIIGAVGLSFFGGAVVNGDSANITTLFSDGNKGVLAVAVMTPFMYVGFDVIPQAAEEINLPFKKIGQILVLSVVMAVIWYVMIIYGVSLAMDSSALAASKLATADAMKAVFFDSPLASKIMVIAGIGGIITSWNSFFVGGSRAIYSMADSKMLPEFLGKLHPKYKTPVNAVLLIGILSTLAPLLGRKMLVWLVDAGGFTIVISYLIVSISFIVLRYKEPDMPRPYKVRKGVLVGSIAVLLSGLCIFLYLPGAPSALVSYEWAIVTGWFVLGAVFYTWSKMSYVEFGKHAEEEALG
>NC_014633.1|WP_013389014.1|732776_734120_-|4-aminobutyrate--2-oxoglutarate-transaminase
MILEKNAKITTAIPGPKSKELLEKRLKYVARGVSYSTEVFVDEAKGALIKDIDGNVFVDFAAGIGVQNVGHCDEEIVETIKSQVEKNIHTSFNVAMYEPYINLAEKLVAATPGDYDKKALLINSGTEAVENAVKIARKYTGKPMILSLENAFHGRTYMSMTLTSKVKPYKYGFAPYNSDTHKIPSPYCYRCQFGKKHPGCNLECAQKLEDLLKGELSADMIAALVVEPVQGEGGFIVPPKGYLQRLQKICNDNNILFIVDEIQAGFARTGTLFASEQFDIEPDMMTMSKSLAAGMPLAAVVGKEEIMENPIVGSIGGTFSGNPVACAAAIKVLEKIEKEKLTERANAIGEKIKSRLSEMQKKYPVIGDIRGLGAMCAVEFITDPESKEPNKEIIGKITKESLQEGVIFISAGIYGNVLRFLPPLVMTDEQLEYGLDVLEKSLEKALS
>NC_014633.1|WP_041921399.1|746033_746342_-|CRISPR-associated-endonuclease-Cas2
MRIIVFFDLPTAKKRDRKNYAIFRRFLLNDGYHMLQFSVYSRICNGYDSVKKHIKKLNNNLPPNGSIRVLTLTEKQYVGMELLVSKERSPEEKIGTSKTIII
>NC_014633.1|WP_013389025.1|746346_747249_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRNIFITSSTKISTRDSGLLITKEGGEVNIPLEDISSIILDNNSVTITSRVLEEIASRDIVLLTSDEKHLPNGIFQGYGRHSRQLAVAKAQINMSVPRKKRLWQEIVTKKLENQGRVLELMRCEGSKYLYDLSKRVKSGDDGNLEALGAKYYFQKLFGDDFTRRDHDIKNFALNYGYAVIRGRIARSLTSYGYICSLGIQHKNEYNAFNLADDIIEPYRSVVDLWVANNIDKLSDELTTDNKVSLVEILNADVKLTGKKYSVNISIDEVIKRYTKCIRGKGGNLILPSIIPIQEHRYV
>NC_014633.1|WP_013389026.1|747262_750541_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKYSIGLDIGIASVGWSVINKDKERIEDMGVRIFQKAENPKDGSSLASSRREKRGSRRRNRRKKHRLDRIKNILCESGLVKKNEIEKIYKNAYLKSPWELRAKSLEAKISNKEIAQILLHIAKRRGFKSFRKTDRNADDTGKLLSGIQENKKIMEEKGYLTIGDMVAKDPKFNTHVRNKAGSYLFSFSRKLLEDEVRKIQAKQKELGNTHFTDDVLEKYIEVFNSQRNFDEGPSKPSPYYSEIGQIAKMIGNCTFESSEKRTAKNTWSGERFVFLQKLNNFRIVGLSGKRPLTEEERDIVEKEVYLKKEVRYEKLRKILYLKEEERFGDLNYSKDEKQDKKTEKTKFISLIGNYTIKKLNLSEKLKSEIEEDKSKLDKIIEILTFNKSDKTIESNLKKLELSREDIEILLSEEFSGTLNLSLKAIKKILPYLEKGLSYNEACEKADYDYKNNGIKFKRGELLPVVDKDLIANPVVLRAISQTRKVVNAIIRKYGTPHTIHVEVARDLAKSYDDRQTIIKENKKRELENEKTKKFISEEFGIKNVKGKLLLKYRLYQEQEGRCAYSRKELSLSEVILDESMTDIDHIIPYSRSMDDSYSNKVLVLSGENRKKSNLLPKEYFDRQGRDWDTFVLNVKAMKIHPRKKSNLLKEKFTREDNKDWKSRALNDTRYISRFVANYLENALEYRDDSPKKRVFMIPGQLTAQLRARWRLNKVRENGDLHHALDAAVVAVTDQKAINNISNISRYKELKNCKDVIPSIEYHADEETGEVYFEEVKDTRFPMPWSGFDLELQKRLESENPREEFYNLLSDKRYLGWFNYEEGFIEKLRPVFVSRMPNRGVKGQAHQETIRSSKKISNQIAVSKKPLNSIKLKDLEKMQGRDTDRKLYEALKNRLEEYDDKPEKAFAEPFYKPTNSGKRGPLVRGIKVEEKQNVGVYVNGGQASNGSMVRIDVFRKNGKFYTVPIYVHQTLLKELPNRAINGKPYKDWDLIDGSFEFLYSFYPNDLIEIEFGKSKSIKNDNKLTKTEIPEVNLSEVLGYYRGMDTSTGAATIDTQDGKIQMRIGIKTVKNIKKYQVDVLGNVYKVKREKRQTF
>NC_014633.1|WP_013389027.1|750837_752196_-|MATE-family-efflux-transporter
MEKIKRLGEEKISKLLVEFSLTAIISSLVFALYNVVDRMFIGKCLGPYAMAGISITFPIFTIYIAVGMLVGHGGGSIVSLRLGQGRKEEADRVLGNVFTLYGVFSIILMTLGYLLMDRLMIIFGATENTIIYAKDYLYIINFLVLFDFIAMGVNNLLRSEGNPKFSMIIMIVGALTNVFLDFIFIFVLDYGIKGAAMATAIANIVGSIMVLYHFIYSDRSNIKLKLKYLKPDFKIIKEIFSIGISPFTLQLANSLVAVFANRALLIYGGDMAVGAMGAINSVFMFLMMTLSGIIQGAQPLLGYNYGAQKYDRVKKILNMALLYGVIISLVLTALIMIKPEFFINLFNNGNEELLEIGKSGIRIFMALVVFNAIYVVGANYFQAVGQANKSLFLNIFKQLGLFIPLIIILPKYFGLNGIWFAAPVSDVIIFMITGVFLLKNNKKLKKLSVQYA
>NC_014633.1|WP_013389028.1|752183_752636_-|MarR-family-transcriptional-regulator
MKEPLGRTVKFLNIEIRKFLDFHLNEYQLGNGQFAIVIEVSENKGINQDALAQKMGVDKTTIAKTVKKLVENGYIIKEEDENDRRSKKLYTTHKADLIFKKIKKLINLEKQVLTHGISQEEIKIFLKVVDCMKSNISEYLESGGSSDWKK
>NC_014633.1|WP_013389029.1|752841_753354_+|ribonuclease-E-activity-regulator-RraA
MSEKLDTHGTAEICDIHRENIQVFQPMSFKSYGGKTRCSGEIVTVSLYEDNSTLKTLLQTPGNNRIAVAKVSGDFCAVVGDNLCKFAIDNGWGGIIIDGFVRDTNMLKTMPMTVLAMGTYPLRSSKKSQGKIGDTLEIAGVKVDHGSYLYLDEDGILVTKEKFSDINFVK
>NC_014633.1|WP_148223746.1|753421_753883_-|HD-domain-containing-protein
MISYFGKDVRRINHALKVYCFAKSIGESENLDSEKQKILEISAILHDIGIKISEEKYNSSAGKYQELEGPDVARKLIKDIDLSEKIKERICYLIGNHHSYDKIDGIDFQILVEADFLVNIYEDKLNSETAATVKKKYFETKTGREYISSLYGV
>NC_014633.1|WP_013389031.1|753931_754582_-|HAD-hydrolase-like-protein
MKKFDLVIFDLDGTLTDSRVGITKSVSYALDKMGIKPTSLKELEHFIGPPLMDTFMGHYKFSKCDSEKAVNLFRERYSEKGLYENIPFHNINTLLSDLKKSGMKLAVATSKPQHFSEKILDHFLLSQYFDEIIGSSLDNSFSHKNEIIAETLKRFPGISKEKTVMVGDRKFDIEGARENGILSIGVKYGFADPGEIDAACPQFQADNVEDLFKILL
>NC_014633.1|WP_013389032.1|754793_754988_-|DUF4250-domain-containing-protein
MEIKNMKSMDPNLLLSIVNMKLRDEFESLDDLLRYYNLKESDLTDKIKEIGYHYCEETNQFIGC
>NC_014633.1|WP_013389033.1|755078_755963_-|ABC-transporter-substrate-binding-protein
MKFKIAVIWMLITINVFAYEVMEGSKPRKLEKSYQRIISIYPAHTEVILDLGGKSKLVGTVKEKGISERTQGIKGFSYNDSLEKYLSVRPDLVIIRPMYRDKNKNLFKRLESMGITVVSLQPVSYNDLERYWMDIGRLIGRENAGKEYVNKYRKGLESIGVQDRKRKKVFFEARMQNGLYTASKESIAHFIIEKAGGDILTGNEEPLRKGTSTITPVNMEYLISQGSAIDTYLVQQGRMNSRTKEDIKKTPGYSSIKAVKTGSIYMIDEGALSRPTIKILDAMKEIKKILSKQS

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Crispr_ID: NC_014633_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014633_3

793061-793157

Orphan

Consensus_repeat	Method
CCGAAGGAGTAAAACTCTCAGGTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014633_3

>merge|NC_014633|3|793061-793157|CRISPRCasFinder
CCGAAGGAGTAAAACTCTCAGGTAAAAGGACCTATTCTGGACGAGCCTCTGGAGAGAACTGTTTAGTCAGTCGCCGAAGGAGTAATACTCTCAGGTA

>NC_014633|3|3|793061-793157|CRISPRCasFinder
CCGAAGGAGTAAAACTCTCAGGTA	AAAGGACCTATTCTGGACGAGCCTCTGGAGAGAACTGTTTAGTCAGTCG
CCGAAGGAGTAATACTCTCAGGTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014633.1\|WP_013389063.1\|789489_790077_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_014633.1\|WP_013389059.1\|782065_784540_+\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|163244
NC_014633.1\|WP_013389069.1\|795836_797174_-\|rhodanese-domain-containing-protein	unknown	unknown	gnl\|CDD\|225450
NC_014633.1\|WP_013389062.1\|787907_789302_-\|phospholipase-D/transphosphatidylase	unknown	unknown	gnl\|CDD\|197227
NC_014633.1\|WP_013389057.1\|780989_781445_-\|hypothetical-protein	unknown	unknown	unknown
NC_014633.1\|WP_013389074.1\|800607_801009_-\|PhnA-protein	unknown	unknown	gnl\|CDD\|129018
NC_014633.1\|WP_187288125.1\|798462_799134_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223673
NC_014633.1\|WP_013389064.1\|790199_790991_+\|4Fe-4S-binding-protein	unknown	unknown	gnl\|CDD\|319871
NC_014633.1\|WP_013389075.1\|801254_802367_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|182165
NC_014633.1\|WP_013389076.1\|802342_803281_+\|pseudouridine-5'-phosphate-glycosidase	unknown	unknown	gnl\|CDD\|377251
NC_014633.1\|WP_013389067.1\|793285_794347_+\|low-specificity-L-threonine-aldolase	unknown	unknown	gnl\|CDD\|99748
NC_014633.1\|WP_013389071.1\|797761_798466_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NC_014633.1\|WP_013389070.1\|797442_797724_+\|DUF1540-domain-containing-protein	unknown	unknown	unknown
NC_014633.1\|WP_013389066.1\|792082_792826_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|372995
NC_014633.1\|WP_013389058.1\|781825_782044_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|273625
NC_014633.1\|WP_013389061.1\|786321_787605_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NC_014633.1\|WP_013389073.1\|799183_800023_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223787
NC_014633.1\|WP_187288124.1\|784796_785435_-\|Hpt-protein	unknown	unknown	gnl\|CDD\|234799
NC_014633.1\|WP_041921301.1\|785523_786189_+\|leucine-rich-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|275380
NC_014633.1\|WP_013389068.1\|794400_795795_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224169

Protein	Function_ID	Function_description	E-value
NC_014633.1\|WP_013389063.1\|789489_790077_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.42142e-16
NC_014633.1\|WP_013389059.1\|782065_784540_+\|CoA-disulfide-reductase	gnl\|CDD\|163244	TIGR03385, Coenzyme_A_disulfide_reductase, CoA-disulfide reductase. Members of this protein family are CoA-disulfide reductase (EC 1.8.1.14), as characterized in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi, and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. [Cellular processes, Detoxification].	9.37411e-152
NC_014633.1\|WP_013389069.1\|795836_797174_-\|rhodanese-domain-containing-protein	gnl\|CDD\|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.43147e-45
NC_014633.1\|WP_013389062.1\|787907_789302_-\|phospholipase-D/transphosphatidylase	gnl\|CDD\|197227	cd09129, PLDc_unchar2_1, Putative catalytic domain, repeat 1, of uncharacterized phospholipase D-like proteins. Putative catalytic domain, repeat 1, of uncharacterized phospholipase D (PLD, EC 3.1.4.4)-like proteins. PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain two HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily. The two motifs may be part of the active site and may be involved in phosphatidyl group transfer.	4.60978e-93
NC_014633.1\|WP_013389074.1\|800607_801009_-\|PhnA-protein	gnl\|CDD\|129018	smart00782, PhnA_Zn_Ribbon, PhnA Zinc-Ribbon. This protein family includes an uncharacterised member designated phnA in Escherichia coli, part of a large operon associated with alkylphosphonate uptake and carbon-phosphorus bond cleavage. This protein is not related to the characterised phosphonoacetate hydrolase designated PhnA.	0.000236459
NC_014633.1\|WP_187288125.1\|798462_799134_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	8.95347e-33
NC_014633.1\|WP_013389064.1\|790199_790991_+\|4Fe-4S-binding-protein	gnl\|CDD\|319871	cd10549, MtMvhB_like, Uncharacterized polyferredoxin-like protein. This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.	7.67868e-13
NC_014633.1\|WP_013389075.1\|801254_802367_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|182165	PRK09954, PRK09954, sugar kinase.	5.53632e-73
NC_014633.1\|WP_013389076.1\|802342_803281_+\|pseudouridine-5'-phosphate-glycosidase	gnl\|CDD\|377251	pfam04227, Indigoidine_A, Indigoidine synthase A like protein. Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.	0
NC_014633.1\|WP_013389067.1\|793285_794347_+\|low-specificity-L-threonine-aldolase	gnl\|CDD\|99748	cd06502, TA_like, Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a secondary glycine biosynthetic pathway.	2.86379e-118
NC_014633.1\|WP_013389071.1\|797761_798466_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	7.28957e-68
NC_014633.1\|WP_013389066.1\|792082_792826_-\|HNH-endonuclease	gnl\|CDD\|372995	pfam14279, HNH_5, HNH endonuclease. This domain is related to other HNH domain families such as pfam01844. Suggesting that these proteins have a nucleic acid cleaving function.	5.25581e-06
NC_014633.1\|WP_013389058.1\|781825_782044_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|273625	TIGR01439, Uncharacterized_protein_Mb2626, looped-hinge helix DNA binding domain, AbrB family. This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609. [Regulatory functions, DNA interactions].	6.81576e-10
NC_014633.1\|WP_013389061.1\|786321_787605_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	9.12539e-159
NC_014633.1\|WP_013389073.1\|799183_800023_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	6.32692e-11
NC_014633.1\|WP_187288124.1\|784796_785435_-\|Hpt-protein	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	2.91955e-06
NC_014633.1\|WP_041921301.1\|785523_786189_+\|leucine-rich-repeat-domain-containing-protein	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	1.7069e-09
NC_014633.1\|WP_013389068.1\|794400_795795_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224169	COG1249, Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion].	1.11982e-145

>NC_014633.1|WP_013389066.1|792082_792826_-|HNH-endonuclease
MINVIFFWMAVFIIIFIFTRKSKSPYGDKKDGGILGSEKINFDNIKRKEIKVFFDDKLTDSEKLKLYGIFENKCFKCSSTEHLSIDHHIPISKGYPLKDKEAGLNAVVLCEKCNRKKGDTLPDEYYKKYELIRLENLGVKSHLYYSSKRIKEVEKNLLSYKLDFLRESIDKKEKIKFVYLNQEEILFTREGVEIHPFKISAERKLLYRGWIREWYLFSEENRERPFNIRWIYHLERSSGRISIKNKC
>NC_014633.1|WP_013389064.1|790199_790991_+|4Fe-4S-binding-protein
MKILYFTATGNSLYISKALGGELLSIPQMVKEEKFEFTDEKIGIVFPVYGWGVPSYIVDFLRKAKFDTDYLFAVPTYGVYSGAVANHLTDISKNTGYEFSYINPIKMVDNYLPGFDMKKEAANKGKKGTEENLITIKADVASSKKWIKAENFLQKGAFNIMHKRKKPFSKKQLKIHTYGEGIENYVYTDENCTGCGLCAKVCPVDNIIVDKENKKIALQDKCFGCFACIQNCPSRAIHIRGEVNGNRYRHHHIRVSEIIEANS
>NC_014633.1|WP_013389063.1|789489_790077_+|TetR/AcrR-family-transcriptional-regulator
MDDKKTKILEKAKELFLIYGVKKTTVDEIAKAAGVGKGTVYLYFTSKGDIVSDLAVQEANSIASQLNDVIEKENSAEEKLRVFIKSFILNCHDFVNSNRHAADIFDVIRQHRSKCEINDQSYEGEMAEITKISSEILLAGKEKDAFIFDDLLELIGNMSFALQSYFPPFSNSLSREELDKKSDYIIDIIIKGLKQ
>NC_014633.1|WP_013389062.1|787907_789302_-|phospholipase-D/transphosphatidylase
MEIMKKSNIIYIILLIMIMGCTRVPKGTSIKGTPYYTEKVDFLKDMTYMKDGERHVEQEILDYALDIIDSAEDFIVVDMFLYNSIYDKDKEFPEITKKVTEKLIEKKKEGLEVYLITDEINTFYKVYDIWEFQVLRKAGIKIIETDMTKVRDSNITYSILWRTVFKWFGTGGIGWVKNPFSEDAPKVTVRGYLKLLNLKANHRKVVVSEKKALVASMNFHDASGYHSNIGFGVEGPVIKEILTSEIDVASFSGEDISLEIQNPEVKGGEIKVALLTEKMIGENIENLIKASESGDEIKIGIFYLGDRRIIRELINAGERGVKIKIILDANIEAFGRHKNGIPNRLVAWELTKKGGENIEVRWYKTSGEQFHSKFIISNKKDEVAIIGGSANFTKRNIQGYNLETDLMLEASKKNELSLAVNVYFDNMWGNIGGEYTLPYEEKADESYVKYFLYRFQEFSGWSTF
>NC_014633.1|WP_013389061.1|786321_787605_-|NCS2-family-permease
MEKFFKLKEHGTNVRQEVVAGITTFLTMAYIIFVNPAILSAAGMDKGALITVTCLAAFIGTAFAGLWVNVPFAMAPGMGLNAFFTYTLVMGHGATWQEALGVVFISGIIFLILTFTGFREKIIDAIPSQLRLAVGAGIGLFIAFIGMQNMGLIVSNPATLVGLGELNLPVLLGLIGLAVMGYLEMKRVKGGILVGIIVTTVLGIVFKEVALPSSVIAMPPSIAPIAFKLNILGALKISLFGTIFSFMFVDLFDSVGTIMACAHEAEMIDEKGKIQNVSKLLEADAMATVIGSLLGTSTTTTYVESASGIAEGGRTGLTAITTAVLFIVALFFAPLIGIVPAFATAPALILVGIYMFKNLLDIDFHDIEVAIPSFLTIILMPLTYSISTGIAFGFISYVAVSIFSGDLKKIKPTMWFIGILSVVELIF
>NC_014633.1|WP_041921301.1|785523_786189_+|leucine-rich-repeat-domain-containing-protein
MDGIELFVDLEVLNLENNEIQSLDGIENLTNLKRLYLRGNPLTASDLEILLKLKNLQFLSFSNVPGNYLDVLYVFIPDKNLKSSVWENIQTFSEYTSTADKITFEDAEKITELYCKGKDIKNLRGIENFINLEILDLEENMIRTLYKIDFSKLHKLEYLNIAGNEIYSLEKFEEFLPVPDKELDIYFQKDDYTNPVISSSSFPNVIKKIKRKFNNKIQLII
>NC_014633.1|WP_187288124.1|784796_785435_-|Hpt-protein
MLDDEIELLEVLELLSELEELLESSDDELESLEVLELLSELEELLESSDDELESLEVLELLSELEELLESSDDELESLEVLELLSELEELLESSDDELESLEVLELLSELEELLESSDDELESLEVLELLSEPDELLESSDDELESLELVELLSEPDEDVVVISIPSVTERMTVSPVFLFNIVSVQAASIPRLINKNTVKIINFLYMFAPPP
>NC_014633.1|WP_013389059.1|782065_784540_+|CoA-disulfide-reductase
MKILIVGGVAGGASAAARLRRINEDAEIVMFERGEYISFANCGLPYHIGGVIKERDNLLVQTIEGMKTRFNIDVKIKTEITKIDKENKKVYAKNLKTGETFEESYDRLLLSPGAAPFIPPIPGVNSPNIFSLRNMNDMDSIISHIEKNSVKRAVVVGAGFIGIEVAENLLERDIEVSILEKAPQVLTMVDEEIAAQVHQNIKDKEVELYLEDGVTQFEDIEGKTVVKLESGKKITADMVVMAIGVKPENDLAKEAGLETGKKGGVTVNKYLQTSDENIYAVGDAIEVKHYLSGEESIIPLAWPANRQGRIVADNMLGINLKAYNGSLGTSIIKAFDTTVAATGLNERYLKNAGTEYMVATVNRNSHASYYPGGVPITLKLIFTKDGDILGAQGLGCKGVDKRIDVIATAIKGKMKVWDLQDLELAYAPPYNSAKDPVNILGYVAENMINGEVETISYFQIEDYLKNNNAQLLDIRTKDENELGSIPNSTHIDLAELRDNLSKLDKDKEYLVYCQVGLRGYIAYRMLVQHGFKAKNLDGGYKLWQYTVMDQSNRDVFEKINDFKHKEASCCGTVSELIDEEREMNKIIEVDACGLQCPGPILKTKKTMETIKDGEVLSIKSTDTGFKKDIATWAEKTGNKLLDVQLENGIVTAHVKKGSESKNLTPIAEKDTQTMVVFSGDLDKILASFIIANGALAMGKKVSMFFTFWGLNALRKENYTNKNKGVIDKMFGMMMPKGVNKLKLSKMNMGGMGTAMMKYVMKEKNVDSLEKLMKTYLENGGKITACTMSMDVMGIAKEELIDEIDYGGVASYLGDSQESYSNLFI
>NC_014633.1|WP_013389058.1|781825_782044_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MLEFKDGKCICGTVTVGERGQIVIPKKARDYFDIQPGDQLVVLGDKSKGITVFKAGDLKEFANFILNNANDE
>NC_014633.1|WP_013389057.1|780989_781445_-|hypothetical-protein
MKKFLLSVIISSFLVSCMTVKNDRAIKSKESSENSVLLSEKITDIDPIDYLKSLAINPDNPVVVEPVDSKTWIKEEDLAKLMAQIESDEPASPVVSILSSYYPFNKQSTVGNEAMFMVEGYIVGQYPPKLCSVYYFHVDVDYYRGWWSSQE
>NC_014633.1|WP_013389067.1|793285_794347_+|low-specificity-L-threonine-aldolase
MERTFASDNFSGVDPKIMEKLMEANQGHAFAYGMDPLTIKAKEKFKEIFGDVEVFFVFNGTGCNVLALEAMKGRATCVLCPDTAHIFQDEAGAPSKITGMQLLPVPSEDGKFSIKAAEKFLSFKGAIHKPEAHIISITQATELGTVYTPAEIKNISAFAKRNNMLLHMDGTRLSNAAAALGCSLKEMTADCGVDVLSFGGTKNGLMFGEAIVFFNKELAKDFFRLRKQNLQLHSKMRFISAQYLGLLEDNLWHTNASKANSMAKYLKKKLVNLGVEVTNDVMANIVFAKIPMDAVEEMQEFSYFYLWNEYKKESRFVMSFDITEEDIDIFVDKLEDVLKKQSIYLSEGTCCAS
>NC_014633.1|WP_013389068.1|794400_795795_+|NAD(P)/FAD-dependent-oxidoreductase
MTFDFDLIVIGAGAAGLTCAITAKGFGKSVLLIEKNRTGGECTWSGCVPSKALINISKEINSARKYCDFVPDTRKIMKDVKKVIEDVYSHETPEVLEKTGINFLEGEAEFTENKTIKIGENTFSGKSIIIATGSSPFVPPIPGINTVEYLTNESLFLLEEIPKSMIILGGGAIGVEMAQALNRIGVEVHLVEMLDNILFREDQEFAHILREKLIDEGVNIHIKTKAVEVKKNNNTIILTVEKDGQKSELSAESMLVAVGRKPSTASLKLENAGIEYNKKGIEVDKHLETNIHNIYAVGDVVGPYQFSHMANYQGIIAVQNALTPLKKSIDYSNVAWTTFTQPELASAGMSEKEAREKHDNIHIYSLKRDELDRAKTKKDDIFNVKIICDHKKKILGAQILADRAGELICEIQAMKSNGLSLDKLAGVIHPYPTYAEAFSKLGKKAYVDKLMDNPVVSLIKSIKH
>NC_014633.1|WP_013389069.1|795836_797174_-|rhodanese-domain-containing-protein
MKKILLVLSVMLFVIGCSNKSENPGEVSKKIEVLSTRKVKKSLKNQNTVLIDTRSYDEYNGWDIKETGIQGHISGAYNLPASSLEHGDIEDFLDRKGITKDNEIILYGDDISMSEVLSDKGYNVYVYEKGIKEWTEKKNSIEKLPKYESLVPVSWVKKLLEGKEVPEYDGRPVKVINAGWGKKGKFHKNGHIPGSYYVHTGWFEVGPLWNRVSDENIKAELEKLGITKETLVIVYGEDPMPAARFAIICKYAGVEDVRVVNGGWKAWQEAGYSTEEGIEYPQPVDDFGTEVPGNPDIIIDLPEAENYLKSDQSDLVSIRSWKEYIGKTSGYDYIKPRGRIRGDKWGMGGSDPWHLEDYRAEYGTYMRPYNEILEMWEDLKINTDKNIAFYCGTGWRASEVLFYADAMGLDKVSLYEGGWKEWSENPETENEILKGEPEKLNEEKY
>NC_014633.1|WP_013389070.1|797442_797724_+|DUF1540-domain-containing-protein
MKMSQVLDCDAVNCIYNKDKKCHTLAVNIGDKEPLCDTFMTGASKGGFDDVIGGVGSCKVSECSFNKSYECMSTGVHMSIVGDHVDCKTYHKK
>NC_014633.1|WP_013389071.1|797761_798466_-|ABC-transporter-ATP-binding-protein
MIKVENIYKNYDSKVIMKDFNINFEKNKVSVLLGSSGCGKSTLFNMLSSLDKEYRGKILIDGKVSYIFQEDRLIPWLTVEENLSLISSQEKDINGVLEKFHVESKAKTLARNLSGGEKQRVSIARAFYHGGEIILMDEALRSLDMLLKLKIIEEISDNISHESKTMVIISHDIQEALLIGDRIFILDKDPMNIVESYDINTPRKNRILKSGELLDLEKEIYQKLLGEKSKMLSE
>NC_014633.1|WP_187288125.1|798462_799134_-|ABC-transporter-permease-subunit
MKLDPLILPSPISILNVFRNNILTGKGIAETCITLYRFFMAYSVSVSLGILCGMLIFKNSTVKSFLWPFITILQSTPVISWVLLALLWFPSEIIPYFILGIFTLPVIIINTFNGLMSTDEKLLEMASAYGIEEKQVFSKIMLPSMLSSLMGGIKITANSSLKVLATAEIIGRLPRGIGGEMNTAWINIETDSLLAWTIYLIILTGLLEKLISKAIKIKWGRYL
>NC_014633.1|WP_013389073.1|799183_800023_-|ABC-transporter-substrate-binding-protein
MKKIIASVFMIVSLAVWGLEIDAPKAPPSIPLLAIEDININFYQNVSTEVVPKIIRKKGELYIIPVNVAATLYNKGVDIRLLGITSRGLLSFLSKDIEKIVDLEGKKLYIGGQGSSPDVVMKNILEKKNISLDISYRSSGEIAKLAMAGKIDNLVLPEPLATMVLSKNKNFKRVTELKDLWKGKEIPQVGIFVMGKVYDENPIEVDKIIEKYKKALERKNEVKLLERAIEEFSLKLSIGDLEESVRYMNLTLDTGCKKSVEHYLDALGIKLPGDEFYAW
>NC_014633.1|WP_013389074.1|800607_801009_-|PhnA-protein
MAKGLDRDRERKSKVLFFGKDLARRSKSSCELCEAKNESLKIYEVPPINEEPQFEQCMFICEQCSKILDNLNKAGENDLRFLNSAVWSEVPIVKAVAIYALRKIKDKYTWAEETLETVYIEEEVESLLEKIEI
>NC_014633.1|WP_013389075.1|801254_802367_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MTDREKDVFDLINSNPLVSQEEISERLKIARSSVAVHISNLMKKGYILGKGYVLKDAPYTAVLGGANIDIEGTPIGSLKMRDSNPGIVNKSFGGVARNIAENISKIGIDTKLLTLVGDDSHGNDLLDYCRKKGIDTSYSLSLQGKSTSTYISILDKNKDMAVAISHMDIMTKMDISFITKRASVIQGSSLCVVDTNIPFETLEYILKNFIKTKFIVDTVSLEKSKKIKNLLPYIDTLKPNKIEAEELSGININTKQDVEKAAEIIVEKGVKNIFISLGKEGVYYFNGGDKGFIKPPEIEVTTATGAGDAFIAGVIYGKSERENIKKQAIYGVSASIAVLTNGKDRENNLNIDKINKIFKEVKRCNSMKNI
>NC_014633.1|WP_013389076.1|802342_803281_+|pseudouridine-5'-phosphate-glycosidase
MQFYEKYLDISPEIEKALEKGTPVVALESTIISHGMPYPENVETALNVEKIIRENGAIPATIAILNGRLKVGLSKDEIDFLGKTGLDAVKTSRRDLPFIISKKLTGATTVASTMIIASFAGIRIFATGGIGGVHRGAETTFDISADLQELANTNVAVVCAGAKSILDIGLTLEYLETNGVPVVGYQTDELPAFYTRKSGFKVDYKVDNPKEIALALKAKWELGLNGGMVIANPIPEEYSMDNKLITHVIENALIEAEKKNIKGKESTPFLLAKVKELTEGKSLESNIQLVYNNAKLAAEISKELAALNHVKY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014633_1	1.1\|271858\|47\|NC_014633\|CRISPRCasFinder	271858-271904	47	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	271858-271904	0	1.0
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	744618-744647	0	1.0
NC_014633_2	2.2\|744684\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744684-744713	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	744684-744713	0	1.0
NC_014633_2	2.3\|744750\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744750-744779	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	744750-744779	0	1.0
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	744816-744845	0	1.0
NC_014633_2	2.5\|744882\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744882-744911	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	744882-744911	0	1.0
NC_014633_2	2.6\|744948\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744948-744977	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	744948-744977	0	1.0
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745014-745043	0	1.0
NC_014633_2	2.8\|745080\|28\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745080-745107	28	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745080-745107	0	1.0
NC_014633_2	2.9\|745144\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745144-745173	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745144-745173	0	1.0
NC_014633_2	2.10\|745210\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745210-745239	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745210-745239	0	1.0
NC_014633_2	2.11\|745276\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745276-745305	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745276-745305	0	1.0
NC_014633_2	2.12\|745342\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745342-745371	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745342-745371	0	1.0
NC_014633_2	2.13\|745408\|29\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745408-745436	29	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745408-745436	0	1.0
NC_014633_2	2.14\|745473\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745473-745502	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745473-745502	0	1.0
NC_014633_2	2.15\|745539\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745539-745568	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745539-745568	0	1.0
NC_014633_2	2.16\|745605\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745605-745634	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745605-745634	0	1.0
NC_014633_2	2.17\|745671\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745671-745700	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745671-745700	0	1.0
NC_014633_2	2.18\|745737\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745737-745766	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745737-745766	0	1.0
NC_014633_2	2.19\|745803\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745803-745832	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745803-745832	0	1.0
NC_014633_2	2.20\|745869\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745869-745898	30	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	745869-745898	0	1.0
NC_014633_3	3.1\|793085\|49\|NC_014633\|CRISPRCasFinder	793085-793133	49	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	793085-793133	0	1.0
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	LN835295	Clostridium perfringens plasmid pJIR4150, complete sequence, strain JIR12708	69688-69717	5	0.833
NC_014633_2	2.8\|745080\|28\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745080-745107	28	MN692981	Marine virus AFVG_117M36, complete genome	10125-10152	5	0.821
NC_014633_2	2.2\|744684\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744684-744713	30	NZ_CP027525	Pseudoalteromonas carrageenovora strain KCTC 22325 plasmid pKCTC22325, complete sequence	32570-32599	6	0.8
NC_014633_2	2.6\|744948\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744948-744977	30	AP011616	Thermus phage phiYS40 DNA, complete genome	79272-79301	6	0.8
NC_014633_2	2.6\|744948\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744948-744977	30	DQ997624	Thermus thermophilus phage YS40, complete genome	79273-79302	6	0.8
NC_014633_2	2.6\|744948\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744948-744977	30	NC_015937	Thermus phage TMA, complete genome	79148-79177	6	0.8
NC_014633_2	2.6\|744948\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744948-744977	30	NC_008584	Thermus phage phiYS40, complete genome	79273-79302	6	0.8
NC_014633_2	2.6\|744948\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744948-744977	30	AP011617	Thermus phage TMA DNA, complete genome	79148-79177	6	0.8
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MH107028	Campylobacter phage CP39, partial genome	85407-85436	6	0.8
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	NC_015464	Campylobacter phage NCTC12673, complete genome	62869-62898	6	0.8
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	KX236333	Campylobacter phage PC14, complete genome	97862-97891	6	0.8
NC_014633_2	2.13\|745408\|29\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745408-745436	29	NZ_CP045419	Pseudoalteromonas sp. THAF3 plasmid pTHAF3_a, complete sequence	738925-738953	6	0.793
NC_014633_2	2.14\|745473\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745473-745502	30	NZ_CP051678	Spirosoma sp. CJU-R4 plasmid unnamed1, complete sequence	253028-253057	6	0.8
NC_014633_2	2.17\|745671\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745671-745700	30	NZ_CP043858	Arcobacter cibarius strain H743 plasmid pACIB, complete sequence	6695-6724	6	0.8
NC_014633_2	2.17\|745671\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745671-745700	30	NZ_CP026601	Clostridiaceae bacterium 14S0207 plasmid unnamed1, complete sequence	123228-123257	6	0.8
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_MG973074	Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence	48751-48780	7	0.767
NC_014633_2	2.2\|744684\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744684-744713	30	JQ340088	Halocynthia phage JM-2012, complete genome	63735-63764	7	0.767
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	KX349293	Cyanophage S-RIM44 isolate Np_20_0711, complete genome	73604-73633	7	0.767
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	KX349296	Cyanophage S-RIM44 isolate Sn_13_0910, complete genome	73646-73675	7	0.767
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	NC_047734	Cyanophage S-RIM44 isolate Np_42_0711, complete genome	73601-73630	7	0.767
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	KX349291	Cyanophage S-RIM44 isolate ES_42_0910, complete genome	73646-73675	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MK415404	CrAssphage FA1-2_000172F, complete genome	72999-73028	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MK415403	CrAssphage ES_ALL_000190F, complete genome	73741-73770	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MK415410	CrAssphage YS1-2_2437, complete genome	75381-75410	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MK415399	CrAssphage apr34_000142F, complete genome	70468-70497	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MK415408	CrAssphage GF1-2_000079F, complete genome	73766-73795	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MW067003	CrAssphage sp. C0531BW4, complete genome	5132-5161	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MK238400	CrAssphage ZA, complete genome	5095-5124	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MK069403	UNVERIFIED: CrAssphage sp. O-152, partial genome	90933-90962	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	BK010471	TPA_asm: Uncultured crAssphage, complete genome	5131-5160	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MN693124	Marine virus AFVG_25M44, complete genome	26659-26688	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	MW067002	CrAssphage sp. C0526BW15, complete genome	5139-5168	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	NC_024711	Uncultured crAssphage, complete genome	5131-5160	7	0.767
NC_014633_2	2.7\|745014\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745014-745043	30	JQ995537	Uncultured phage crAssphage, complete genome	5131-5160	7	0.767
NC_014633_2	2.12\|745342\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745342-745371	30	AP014260	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S30-C66, * SEQUENCING IN PROGRESS *	16957-16986	7	0.767
NC_014633_2	2.20\|745869\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745869-745898	30	MG592473	Vibrio phage 1.101.O._10N.261.45.C6, partial genome	82261-82290	7	0.767
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_CP042405	Leuconostoc mesenteroides strain CBA3628 plasmid unnamed1, complete sequence	13078-13107	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_CP046063	Leuconostoc mesenteroides subsp. mesenteroides strain CBA3607 plasmid unnamed1, complete sequence	17261-17290	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_CP013017	Leuconostoc mesenteroides subsp. mesenteroides strain DRC0211 plasmid pDSK1, complete sequence	29956-29985	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NC_010470	Leuconostoc citreum KM20 plasmid pLCK1, complete sequence	28518-28547	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_CP028253	Leuconostoc mesenteroides strain SRCM102733 plasmid unnamed2, complete sequence	23618-23647	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_CP042419	Leuconostoc citreum strain CBA3627 plasmid unnamed, complete sequence	29737-29766	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_CP042421	Leuconostoc lactis strain CBA3622 plasmid unnamed1, complete sequence	8296-8325	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NC_018675	Leuconostoc carnosum JB16 plasmid pKLC3, complete sequence	23159-23188	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NC_016827	Leuconostoc mesenteroides subsp. mesenteroides J18 plasmid pKLE01, complete sequence	33722-33751	8	0.733
NC_014633_2	2.1\|744618\|30\|NC_014633\|CRISPRCasFinder,CRT	744618-744647	30	NZ_CP042411	Leuconostoc citreum strain CBA3621 plasmid unnamed, complete sequence	8654-8683	8	0.733
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	NZ_LR214999	Mycoplasma conjunctivae strain NCTC10147 plasmid 3	103357-103386	8	0.733
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	LR214965	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11	92949-92978	8	0.733
NC_014633_2	2.4\|744816\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	744816-744845	30	LR214959	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 5	14803-14832	8	0.733
NC_014633_2	2.17\|745671\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745671-745700	30	NZ_CP030248	Staphylococcus epidermidis strain CSF41498 plasmid pCSF41498_2, complete sequence	16343-16372	8	0.733
NC_014633_2	2.18\|745737\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745737-745766	30	NZ_CP017081	Bacillus muralis strain G25-68 plasmid pG25-68, complete sequence	2512-2541	8	0.733
NC_014633_2	2.20\|745869\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745869-745898	30	NZ_CP014175	Clostridium argentinense strain 89G plasmid pRSJ17_1, complete sequence	16421-16450	8	0.733
NC_014633_2	2.20\|745869\|30\|NC_014633\|CRISPRCasFinder,CRT,PILER-CR	745869-745898	30	MN693739	Marine virus AFVG_250M562, complete genome	4897-4926	8	0.733

1. spacer 1.1|271858|47|NC_014633|CRISPRCasFinder matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

tgcgcttgtaaatggtgcgtgaagggggacttgaacccccaccggga	CRISPR spacer
tgcgcttgtaaatggtgcgtgaagggggacttgaacccccaccggga	Protospacer
***********************************************

2. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
aagttatacttgagtatagaaaaagcggtg	Protospacer
******************************

3. spacer 2.2|744684|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

attctaaatgtgatacccttagttttattt	CRISPR spacer
attctaaatgtgatacccttagttttattt	Protospacer
******************************

4. spacer 2.3|744750|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

gacttggaagagattttatctgcaatagga	CRISPR spacer
gacttggaagagattttatctgcaatagga	Protospacer
******************************

5. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

tttgatttattagaaacctaaagtgattag	CRISPR spacer
tttgatttattagaaacctaaagtgattag	Protospacer
******************************

6. spacer 2.5|744882|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

aagaggggaaaaactaacctctctttttgt	CRISPR spacer
aagaggggaaaaactaacctctctttttgt	Protospacer
******************************

7. spacer 2.6|744948|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

actagaagaaagtaaagcttggatagactt	CRISPR spacer
actagaagaaagtaaagcttggatagactt	Protospacer
******************************

8. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

aaaatctaaaaacttaatacagtttgcaat	CRISPR spacer
aaaatctaaaaacttaatacagtttgcaat	Protospacer
******************************

9. spacer 2.8|745080|28|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

agagaggattacatagtcaaagatatag	CRISPR spacer
agagaggattacatagtcaaagatatag	Protospacer
****************************

10. spacer 2.9|745144|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

agaagagaaaaggcttcagacagataaagc	CRISPR spacer
agaagagaaaaggcttcagacagataaagc	Protospacer
******************************

11. spacer 2.10|745210|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

ggtggggttgtatatgacagagagtttata	CRISPR spacer
ggtggggttgtatatgacagagagtttata	Protospacer
******************************

12. spacer 2.11|745276|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

cctgcctgcatttggcttttggcctgcttc	CRISPR spacer
cctgcctgcatttggcttttggcctgcttc	Protospacer
******************************

13. spacer 2.12|745342|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

tcactttgtctcaactactccacattttcc	CRISPR spacer
tcactttgtctcaactactccacattttcc	Protospacer
******************************

14. spacer 2.13|745408|29|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

taaaaataacgctacaaagcttacagccg	CRISPR spacer
taaaaataacgctacaaagcttacagccg	Protospacer
*****************************

15. spacer 2.14|745473|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

aaagtgaatgttatacacgctgtcaaagag	CRISPR spacer
aaagtgaatgttatacacgctgtcaaagag	Protospacer
******************************

16. spacer 2.15|745539|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

ctagaggaggtataaatgttcggtgtagga	CRISPR spacer
ctagaggaggtataaatgttcggtgtagga	Protospacer
******************************

17. spacer 2.16|745605|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

aagtaccgccttacagtattcacaatataa	CRISPR spacer
aagtaccgccttacagtattcacaatataa	Protospacer
******************************

18. spacer 2.17|745671|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

attataatttttactatctacctttgataa	CRISPR spacer
attataatttttactatctacctttgataa	Protospacer
******************************

19. spacer 2.18|745737|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

gtatcaagcgatattacatatcagcaaggg	CRISPR spacer
gtatcaagcgatattacatatcagcaaggg	Protospacer
******************************

20. spacer 2.19|745803|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

aaaatcggatggttcatggcatgtagaagg	CRISPR spacer
aaaatcggatggttcatggcatgtagaagg	Protospacer
******************************

21. spacer 2.20|745869|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaaaagaattagattatacaatgggttat	CRISPR spacer
tcaaaagaattagattatacaatgggttat	Protospacer
******************************

22. spacer 3.1|793085|49|NC_014633|CRISPRCasFinder matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 0, identity: 1.0

aaaggacctattctggacgagcctctggagagaactgtttagtcagtcg	CRISPR spacer
aaaggacctattctggacgagcctctggagagaactgtttagtcagtcg	Protospacer
*************************************************

23. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to LN835295 (Clostridium perfringens plasmid pJIR4150, complete sequence, strain JIR12708) position: , mismatch: 5, identity: 0.833

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atcttaaatttgagtatagaaaaagcggtt	Protospacer
*  *** *.********************

24. spacer 2.8|745080|28|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MN692981 (Marine virus AFVG_117M36, complete genome) position: , mismatch: 5, identity: 0.821

agagaggattacatagtcaaagatatag	CRISPR spacer
atagaggattacctagtcaaacatagaa	Protospacer
* ********** ******** *** *.

25. spacer 2.2|744684|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027525 (Pseudoalteromonas carrageenovora strain KCTC 22325 plasmid pKCTC22325, complete sequence) position: , mismatch: 6, identity: 0.8

attctaaatgtgatacccttagttttattt	CRISPR spacer
tctttcaatgtattacccttagttttattt	Protospacer
 .*.* *****. *****************

26. spacer 2.6|744948|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to AP011616 (Thermus phage phiYS40 DNA, complete genome) position: , mismatch: 6, identity: 0.8

actagaagaaagtaaagcttggatagactt	CRISPR spacer
actagaagaaggtaaaccttggatgctcat	Protospacer
**********.***** *******.  * *

27. spacer 2.6|744948|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to DQ997624 (Thermus thermophilus phage YS40, complete genome) position: , mismatch: 6, identity: 0.8

actagaagaaagtaaagcttggatagactt	CRISPR spacer
actagaagaaggtaaaccttggatgctcat	Protospacer
**********.***** *******.  * *

28. spacer 2.6|744948|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_015937 (Thermus phage TMA, complete genome) position: , mismatch: 6, identity: 0.8

actagaagaaagtaaagcttggatagactt	CRISPR spacer
actagaagaaggtaaaccttggatgctcat	Protospacer
**********.***** *******.  * *

29. spacer 2.6|744948|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_008584 (Thermus phage phiYS40, complete genome) position: , mismatch: 6, identity: 0.8

actagaagaaagtaaagcttggatagactt	CRISPR spacer
actagaagaaggtaaaccttggatgctcat	Protospacer
**********.***** *******.  * *

30. spacer 2.6|744948|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to AP011617 (Thermus phage TMA DNA, complete genome) position: , mismatch: 6, identity: 0.8

actagaagaaagtaaagcttggatagactt	CRISPR spacer
actagaagaaggtaaaccttggatgctcat	Protospacer
**********.***** *******.  * *

31. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MH107028 (Campylobacter phage CP39, partial genome) position: , mismatch: 6, identity: 0.8

aaaatctaaaaacttaatacagtttgcaat	CRISPR spacer
aaaagctaaaaaattaatacagtttaaacc	Protospacer
**** ******* ************. * .

32. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_015464 (Campylobacter phage NCTC12673, complete genome) position: , mismatch: 6, identity: 0.8

aaaatctaaaaacttaatacagtttgcaat	CRISPR spacer
aaaagctaaaaaattaatacagtttaaacc	Protospacer
**** ******* ************. * .

33. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to KX236333 (Campylobacter phage PC14, complete genome) position: , mismatch: 6, identity: 0.8

aaaatctaaaaacttaatacagtttgcaat	CRISPR spacer
aaaagctaaaaaattaatacagtttaaacc	Protospacer
**** ******* ************. * .

34. spacer 2.13|745408|29|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045419 (Pseudoalteromonas sp. THAF3 plasmid pTHAF3_a, complete sequence) position: , mismatch: 6, identity: 0.793

taaaaataacgctacaaagcttacagccg	CRISPR spacer
taaaaataacgcaacaaaccttacgtcgt	Protospacer
************ ***** *****. *

35. spacer 2.14|745473|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051678 (Spirosoma sp. CJU-R4 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

--aaagtgaatgttatacacgctgtcaaagag	CRISPR spacer
ccgtaatg--tgttgtacacgctgtcaaagag	Protospacer
  . *.**  ****.*****************

36. spacer 2.17|745671|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043858 (Arcobacter cibarius strain H743 plasmid pACIB, complete sequence) position: , mismatch: 6, identity: 0.8

attataatttttactatctacctttgataa	CRISPR spacer
aagagaatctttactatctacttttgatat	Protospacer
*  * ***.************.*******

37. spacer 2.17|745671|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026601 (Clostridiaceae bacterium 14S0207 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

attataatttttactatctacctttgataa	CRISPR spacer
atagtcattttttctatctaactttgatat	Protospacer
** .* ****** ******* ********

38. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_MG973074 (Clostridioides difficile strain HSJD-312 plasmid pHSJD-312, complete sequence) position: , mismatch: 7, identity: 0.767

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
attttatacttgaatatagaaaaaatgatt	Protospacer
*  **********.**********..*.*

39. spacer 2.2|744684|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to JQ340088 (Halocynthia phage JM-2012, complete genome) position: , mismatch: 7, identity: 0.767

attctaaatgtgatacccttagttttattt	CRISPR spacer
cttctaaatgtgatacctttagacttttac	Protospacer
 ****************.**** .** * .

40. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to KX349293 (Cyanophage S-RIM44 isolate Np_20_0711, complete genome) position: , mismatch: 7, identity: 0.767

tttgatttattagaaacctaaagtgattag	CRISPR spacer
tctgatttattggaaacataaagtgcagaa	Protospacer
*.*********.***** *******   *.

41. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to KX349296 (Cyanophage S-RIM44 isolate Sn_13_0910, complete genome) position: , mismatch: 7, identity: 0.767

tttgatttattagaaacctaaagtgattag	CRISPR spacer
tctgatttattggaaacataaagtgcagaa	Protospacer
*.*********.***** *******   *.

42. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_047734 (Cyanophage S-RIM44 isolate Np_42_0711, complete genome) position: , mismatch: 7, identity: 0.767

tttgatttattagaaacctaaagtgattag	CRISPR spacer
tctgatttattggaaacataaagtgcagaa	Protospacer
*.*********.***** *******   *.

43. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to KX349291 (Cyanophage S-RIM44 isolate ES_42_0910, complete genome) position: , mismatch: 7, identity: 0.767

tttgatttattagaaacctaaagtgattag	CRISPR spacer
tctgatttattggaaacataaagtgcagaa	Protospacer
*.*********.***** *******   *.

44. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MK415404 (CrAssphage FA1-2_000172F, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

45. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MK415403 (CrAssphage ES_ALL_000190F, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

46. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MK415410 (CrAssphage YS1-2_2437, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

47. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MK415399 (CrAssphage apr34_000142F, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

48. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MK415408 (CrAssphage GF1-2_000079F, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

49. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MW067003 (CrAssphage sp. C0531BW4, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacag-tttgcaat	CRISPR spacer
ttaaactaaaaatttaatacagttttgtta-	Protospacer
  ** *******.********* ****. *

50. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MK238400 (CrAssphage ZA, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacag-tttgcaat	CRISPR spacer
ttaaactaaaaatttaatacagttttgtta-	Protospacer
  ** *******.********* ****. *

51. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MK069403 (UNVERIFIED: CrAssphage sp. O-152, partial genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

52. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to BK010471 (TPA_asm: Uncultured crAssphage, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

53. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MN693124 (Marine virus AFVG_25M44, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat---	CRISPR spacer
aaaatttaaaaacttaatacaa---acaaagca	Protospacer
*****.***************.   .***

54. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MW067002 (CrAssphage sp. C0526BW15, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

55. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NC_024711 (Uncultured crAssphage, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

56. spacer 2.7|745014|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to JQ995537 (Uncultured phage crAssphage, complete genome) position: , mismatch: 7, identity: 0.767

aaaatctaaaaacttaatacagtttgcaat-	CRISPR spacer
ttaaactaaaaatttaatacagttt-tatta	Protospacer
  ** *******.************ .* *

57. spacer 2.12|745342|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to AP014260 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S30-C66, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcactttgtctcaactactccacattttcc	CRISPR spacer
tgttcttgtctcaactactttacattttct	Protospacer
*  ..**************..********.

58. spacer 2.20|745869|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MG592473 (Vibrio phage 1.101.O._10N.261.45.C6, partial genome) position: , mismatch: 7, identity: 0.767

tcaaaagaattagattatacaatgggttat	CRISPR spacer
gtaaaagaattatatcatacaatggttatt	Protospacer
 .********** **.********* *  *

59. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_CP042405 (Leuconostoc mesenteroides strain CBA3628 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

60. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_CP046063 (Leuconostoc mesenteroides subsp. mesenteroides strain CBA3607 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

61. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_CP013017 (Leuconostoc mesenteroides subsp. mesenteroides strain DRC0211 plasmid pDSK1, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

62. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NC_010470 (Leuconostoc citreum KM20 plasmid pLCK1, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

63. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_CP028253 (Leuconostoc mesenteroides strain SRCM102733 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

64. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_CP042419 (Leuconostoc citreum strain CBA3627 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

65. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_CP042421 (Leuconostoc lactis strain CBA3622 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

66. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NC_018675 (Leuconostoc carnosum JB16 plasmid pKLC3, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

67. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NC_016827 (Leuconostoc mesenteroides subsp. mesenteroides J18 plasmid pKLE01, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

68. spacer 2.1|744618|30|NC_014633|CRISPRCasFinder,CRT matches to NZ_CP042411 (Leuconostoc citreum strain CBA3621 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

aagttatacttgagtatagaaaaagcggtg	CRISPR spacer
atgttataattgtgtatagaaaaaggaagt	Protospacer
* ****** *** ************ ..

69. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR214999 (Mycoplasma conjunctivae strain NCTC10147 plasmid 3) position: , mismatch: 8, identity: 0.733

tttgatttattagaaacctaaagtgattag	CRISPR spacer
aagaatgatttagaaacctaatgtgattag	Protospacer
   .**   ************ ********

70. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to LR214965 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11) position: , mismatch: 8, identity: 0.733

tttgatttattagaaacctaaagtgattag	CRISPR spacer
aagaatgatttagaaacctaatgtgattag	Protospacer
   .**   ************ ********

71. spacer 2.4|744816|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to LR214959 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 5) position: , mismatch: 8, identity: 0.733

tttgatttattagaaacctaaagtgattag	CRISPR spacer
aagaatgatttagaaacctaatgtgattag	Protospacer
   .**   ************ ********

72. spacer 2.17|745671|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030248 (Staphylococcus epidermidis strain CSF41498 plasmid pCSF41498_2, complete sequence) position: , mismatch: 8, identity: 0.733

attataatttttactatctacctttgataa	CRISPR spacer
taaagaatttttactatcaacgtttgatcc	Protospacer
   * ************* ** ******

73. spacer 2.18|745737|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017081 (Bacillus muralis strain G25-68 plasmid pG25-68, complete sequence) position: , mismatch: 8, identity: 0.733

gtatcaagcgatattacatatcagcaaggg	CRISPR spacer
aaaaaaagctatcttacatatcagcaagta	Protospacer
. *  **** ** *************** .

74. spacer 2.20|745869|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014175 (Clostridium argentinense strain 89G plasmid pRSJ17_1, complete sequence) position: , mismatch: 8, identity: 0.733

tcaaaagaattagattatacaatgggttat	CRISPR spacer
aaaaaagaattgtattatacaatggatgca	Protospacer
  *********. ************.*

75. spacer 2.20|745869|30|NC_014633|CRISPRCasFinder,CRT,PILER-CR matches to MN693739 (Marine virus AFVG_250M562, complete genome) position: , mismatch: 8, identity: 0.733

tcaaaagaattagattatacaatgggttat	CRISPR spacer
tcaaaagaatttgaatatacaatacccttc	Protospacer
*********** ** ********.  .* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

11948 : 32799

Vibrio_phage(25.0%)

portal,terminase,tail,head,protease,plate,capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013388357.1\|11948_12461_-	hypothetical protein	A0A2I7S8P5	Vibrio_phage	1.2e-10	32.6
WP_013388358.1\|12472_12799_-	DUF1353 domain-containing protein	NA	NA	NA	NA
WP_013388359.1\|12805_13543_-	hypothetical protein	NA	NA	NA	NA
WP_013388360.1\|13604_14621_-	hypothetical protein	NA	NA	NA	NA
WP_013388361.1\|14635_14893_-	hypothetical protein	NA	NA	NA	NA
WP_013388362.1\|14927_16085_-	hypothetical protein	A0A0C5AEQ0	Bacteriophage	1.8e-14	33.8
WP_013388363.1\|16086_16692_-\|tail	phage tail protein	A0A0C5AJ63	Bacteriophage	8.8e-18	31.8
WP_013388364.1\|16684_17806_-\|plate	baseplate J/gp47 family protein	A0A059WFM2	Vibrio_phage	2.6e-47	32.4
WP_013388365.1\|17798_18095_-	hypothetical protein	NA	NA	NA	NA
WP_013388366.1\|18091_18565_-\|tail	phage tail protein	A0A2K9V465	Faecalibacterium_phage	1.5e-09	32.8
WP_013388367.1\|18576_19134_-\|plate	phage baseplate assembly protein V	A0A0E3Y4V1	Fusobacterium_phage	4.5e-08	32.0
WP_013388368.1\|19133_20165_-	late control D family protein	R9U464	Rhizobium_phage	4.5e-22	27.9
WP_013388369.1\|20169_20367_-\|tail	tail protein X	A0A0C5AEF4	Bacteriophage	7.8e-08	41.5
WP_013388370.1\|20366_22094_-\|tail	phage tail tape measure protein	A0A1J0MFP9	Staphylococcus_phage	8.9e-63	44.3
WP_013388372.1\|22244_22877_-	hypothetical protein	NA	NA	NA	NA
WP_013388373.1\|22938_23463_-\|tail	phage major tail tube protein	E5G6P8	Salmonella_phage	3.6e-07	26.6
WP_013388374.1\|23474_24923_-	hypothetical protein	A0A0C5AEE8	Bacteriophage	1.4e-82	39.5
WP_013388375.1\|24922_25183_-	hypothetical protein	NA	NA	NA	NA
WP_013388376.1\|25182_25671_-	hypothetical protein	NA	NA	NA	NA
WP_013388377.1\|25667_26231_-\|tail	phage tail protein	A0A067ZG41	Vibrio_phage	5.0e-15	43.0
WP_013388378.1\|26230_26554_-	hypothetical protein	NA	NA	NA	NA
WP_013388379.1\|26562_26865_-	hypothetical protein	NA	NA	NA	NA
WP_013388380.1\|26873_27890_-\|capsid	major capsid protein	A0A0E3U2N5	Fusobacterium_phage	3.2e-44	32.6
WP_013388381.1\|27906_28239_-\|head	head decoration protein	NA	NA	NA	NA
WP_013388382.1\|28238_29324_-\|protease	Clp protease ClpP	A0A067ZG37	Vibrio_phage	2.1e-49	37.3
WP_013388383.1\|29313_30816_-\|portal	phage portal protein	A0A0E3Y693	Fusobacterium_phage	2.0e-95	38.4
WP_013388384.1\|30797_31016_-	hypothetical protein	NA	NA	NA	NA
WP_013388385.1\|31041_32799_-\|terminase	phage terminase large subunit family protein	A0A0E3U2N4	Fusobacterium_phage	3.0e-167	51.4

DBSCAN-SWA_2

109047 : 142285

Bacillus_phage(18.75%)

integrase,terminase,tail,capsid

attL 141063:141079|attR 146317:146333

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013388475.1\|109047_111759_-\|tail	phage tail tape measure protein	NA	NA	NA	NA
WP_013388476.1\|111764_112334_-	phage virion morphogenesis protein	NA	NA	NA	NA
WP_041921274.1\|112338_112620_-	hypothetical protein	NA	NA	NA	NA
WP_013388478.1\|112661_112973_-	hypothetical protein	NA	NA	NA	NA
WP_013388479.1\|113020_113527_-	hypothetical protein	NA	NA	NA	NA
WP_013388480.1\|113541_113982_-	hypothetical protein	NA	NA	NA	NA
WP_013388481.1\|113982_114372_-	hypothetical protein	NA	NA	NA	NA
WP_013388482.1\|114396_115374_-\|capsid	major capsid protein	NA	NA	NA	NA
WP_013388483.1\|115378_115759_-	hypothetical protein	NA	NA	NA	NA
WP_013388484.1\|115763_116633_-	hypothetical protein	NA	NA	NA	NA
WP_013388485.1\|116797_117286_-	hypothetical protein	NA	NA	NA	NA
WP_013388486.1\|117514_117760_+	hypothetical protein	NA	NA	NA	NA
WP_041921275.1\|117762_118152_-	hypothetical protein	NA	NA	NA	NA
WP_013388488.1\|118645_118807_-	hypothetical protein	NA	NA	NA	NA
WP_013388489.1\|118807_121732_-\|capsid	minor capsid protein	B5TA65	Burkholderia_phage	3.8e-13	28.4
WP_041921276.1\|121858_123133_-\|terminase	PBSX family phage terminase large subunit	A0A0M4R5F3	Bacillus_phage	1.7e-140	59.2
WP_013388491.1\|123116_123557_-\|terminase	terminase small subunit	Q4ZCF3	Staphylococcus_virus	4.6e-32	55.8
WP_013388492.1\|123626_123935_-	hypothetical protein	NA	NA	NA	NA
WP_013388493.1\|123961_124342_-	hypothetical protein	A0A2I2L3K7	Orpheovirus	2.0e-31	55.9
WP_013388494.1\|124328_124553_-	DUF3310 domain-containing protein	A0A1B1IWM3	uncultured_Mediterranean_phage	1.1e-18	64.6
WP_013388495.1\|124542_124938_-	hypothetical protein	NA	NA	NA	NA
WP_013388496.1\|124918_125476_-	HTH domain-containing protein	NA	NA	NA	NA
WP_083789132.1\|125475_125685_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_187288126.1\|125736_126306_-	DnaB-like helicase C-terminal domain-containing protein	W8EEZ1	Geobacillus_phage	8.3e-34	46.6
WP_049774891.1\|126323_126989_-	hypothetical protein	D2XR44	Bacillus_phage	1.4e-08	29.3
WP_013388497.1\|126982_127807_-	replication initiator protein A	NA	NA	NA	NA
WP_013388498.1\|128215_128593_+	hypothetical protein	NA	NA	NA	NA
WP_013388499.1\|128584_128779_-	hypothetical protein	NA	NA	NA	NA
WP_013388500.1\|128822_129023_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013388501.1\|129173_129557_-	hypothetical protein	NA	NA	NA	NA
WP_013388502.1\|129728_130112_+	hypothetical protein	NA	NA	NA	NA
WP_013388503.1\|130146_130575_-	type II toxin-antitoxin system death-on-curing family toxin	A0A1X9I6C0	Streptococcus_phage	1.5e-08	33.1
WP_013388504.1\|130576_131596_-	DNA-binding protein	Q331X4	Clostridium_botulinum_C_phage	2.2e-16	29.4
WP_013388505.1\|131624_134552_-	type III restriction-modification system endonuclease	Q71TG1	Escherichia_phage	5.2e-180	40.0
WP_013388506.1\|134551_136702_-	site-specific DNA-methyltransferase	Q1MVP0	Enterobacteria_phage	3.5e-109	38.1
WP_013388507.1\|136649_137360_-	phage repressor	A0A1X9I5R4	Streptococcus_phage	1.8e-14	25.1
WP_013388508.1\|137557_137755_+	hypothetical protein	NA	NA	NA	NA
WP_013388510.1\|137876_138050_+	hypothetical protein	NA	NA	NA	NA
WP_013388511.1\|138133_139240_+	YqaJ viral recombinase family protein	O48490	Bacillus_phage	5.0e-27	32.0
WP_013388512.1\|139252_140119_+	recombination protein RecT	Q0H279	Geobacillus_phage	5.4e-53	43.2
WP_013388513.1\|140184_140487_+	hypothetical protein	NA	NA	NA	NA
WP_013388514.1\|140560_140749_+	hypothetical protein	NA	NA	NA	NA
WP_013388515.1\|140749_141838_+\|integrase	site-specific integrase	Q8SBN2	Clostridium_phage	6.2e-70	41.6
141063:141079	attL	NA	NA	NA	NA
WP_083789133.1\|142018_142285_-\|integrase	tyrosine-type recombinase/integrase	A0A0A8WF08	Clostridium_phage	4.0e-15	59.7
WP_083789133.1\|142018_142285_-\|integrase	tyrosine-type recombinase/integrase	A0A0A8WF08	Clostridium_phage	4.0e-15	59.7
146317:146333	attR	NA	NA	NA	NA

DBSCAN-SWA_3

273412 : 284277

Synechococcus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013388621.1\|273412_274909_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.3e-62	46.2
WP_013388622.1\|275130_275703_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.3e-22	36.4
WP_013388623.1\|275690_276689_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FC27	Synechococcus_phage	1.6e-61	41.8
WP_013388624.1\|276704_278099_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.4e-58	32.5
WP_013388625.1\|278101_278812_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SLB8	Cyanophage	1.3e-41	43.7
WP_013388626.1\|278859_279987_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_013388627.1\|280005_280518_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.7e-20	42.6
WP_013388628.1\|280551_284277_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.9e-33	25.6

DBSCAN-SWA_4

418181 : 427491

Enterobacteria_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013388734.1\|418181_419129_-	ABC transporter substrate-binding protein	G3M9Z0	Bacillus_virus	4.0e-09	26.9
WP_013388736.1\|420609_421182_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	7.8e-48	49.2
WP_013388737.1\|421178_422030_+	dTDP-4-dehydrorhamnose reductase	A0A1D7XFA3	Escherichia_phage	3.5e-28	34.8
WP_013388738.1\|422026_423187_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	5.9e-71	41.3
WP_013388739.1\|423240_423732_-	lipase	F5B430	Synechococcus_phage	8.8e-08	31.9
WP_013388740.1\|423728_424451_-	uracil-DNA glycosylase	A0A1B0WL61	Flavobacterium_phage	8.3e-23	37.0
WP_041921288.1\|424496_425294_-	N-acetylmuramoyl-L-alanine amidase	A0A1B0UZW5	Roseobacter_phage	2.2e-08	49.4
WP_013388742.1\|425399_426239_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_049774896.1\|426219_427491_-	L-aspartate oxidase	M1HTN0	Paramecium_bursaria_Chlorella_virus	9.5e-22	26.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_014632

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_014632_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014632_1

359115-359374

Orphan

Consensus_repeat	Method
AGAAGCTTGTATTGCATGTGGAGCATGTGAAGGAACTTGTCCAGTATCAGC	PILER-CR

2 spacers

The CRISPR arrays of NC_014632_1

>merge|NC_014632|1|359115-359374|PILER-CR
AGAAGCTTGTATTGCATGTGGAGCATGTGAAGGAACTTGTCCAGTATCAGCAATTTCTGCTGCAGACGGTAAATATGAAATTTCAGATGCATGTATCGACTGTGGAGCATGTGCAGGAGTATGTCCTGTAGAGTGTATCACGGCTCAGTAATATCAAAAAATATTTTAAAAAATAAAATAGGGGGTTTTAAAATGTACGTAATCGATAAAGAAGCTTGTATTGCATGTGGAGCATGTGAAGGAACTTGTCCAGTATCAGC

>NC_014632|1|1|359115-359374|PILER-CR
AGAAGCTTGTATTGCATGTGGAGCATGTGAAGGAACTTGTCCAGTATCAGC	AATTTCTGCTGCAGACGGTAAATATGAAATTTC
AGATGCATGTATCGACTGTGGAGCATGTGCAGGAGTATGTCCTGTAGAGTG	TATCACGGCTCAGTAATATCAAAAAATATTTTAAAAAATAAAATAGGGGGTTTTAAAATGTACGTAATCGATAAAGAAGCTTGTATTGCAT
GTGGAGCATGTGAAGGAACTTGTCCAGTATCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014632.1\|WP_013386763.1\|352188_353013_-\|nucleoside-specific-channel-forming-protein-Tsx	unknown	unknown	gnl\|CDD\|367531
NC_014632.1\|WP_041921071.1\|358399_358732_+\|DUF2023-family-protein	unknown	unknown	gnl\|CDD\|378227
NC_014632.1\|WP_013386780.1\|368053_368833_+\|DUF2294-family-protein	unknown	unknown	gnl\|CDD\|381091
NC_014632.1\|WP_083789061.1\|351382_351676_-\|transposase	unknown	unknown	gnl\|CDD\|225511
NC_014632.1\|WP_013386767.1\|355310_355532_+\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|377199
NC_014632.1\|WP_013386775.1\|361066_362185_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367900
NC_014632.1\|WP_013386776.1\|362233_363229_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270234
NC_014632.1\|WP_013386764.1\|353430_354246_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NC_014632.1\|WP_013386770.1\|358092_358380_+\|DUF2325-domain-containing-protein	unknown	unknown	gnl\|CDD\|378383
NC_014632.1\|WP_013386777.1\|363294_363774_+\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815
NC_014632.1\|WP_148223652.1\|359885_360668_+\|hypothetical-protein	unknown	unknown	unknown
NC_014632.1\|WP_013386778.1\|363788_365303_+\|tripartite-tricarboxylate-transporter-permease	unknown	unknown	gnl\|CDD\|225870
NC_014632.1\|WP_013386765.1\|354379_354856_+\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|237999
NC_014632.1\|WP_013386783.1\|370836_371268_+\|hypothetical-protein	unknown	unknown	unknown
NC_014632.1\|WP_013386769.1\|357802_357964_+\|FeoB-associated-Cys-rich-membrane-protein	unknown	unknown	gnl\|CDD\|378908
NC_014632.1\|WP_013386768.1\|355565_357779_+\|ferrous-iron-transport-protein-B	unknown	unknown	gnl\|CDD\|223447
NC_014632.1\|WP_148223653.1\|370218_370710_+\|hypothetical-protein	unknown	unknown	unknown
NC_014632.1\|WP_013386779.1\|365652_368067_+\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|223715
NC_014632.1\|WP_013386781.1\|369512_370259_+\|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl\|CDD\|319354
NC_014632.1\|WP_013386766.1\|354998_355223_+\|FeoA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224830

Protein	Function_ID	Function_description	E-value
NC_014632.1\|WP_013386763.1\|352188_353013_-\|nucleoside-specific-channel-forming-protein-Tsx	gnl\|CDD\|367531	pfam03502, Channel_Tsx, Nucleoside-specific channel-forming protein, Tsx.	2.5687e-32
NC_014632.1\|WP_013386780.1\|368053_368833_+\|DUF2294-family-protein	gnl\|CDD\|381091	cd17536, REC_YesN-like, phosphoacceptor receiver (REC) domain of YesN and related helix-turn-helix containing response regulators. This family is composed of uncharacterized response regulators that contain a REC domain and a AraC family helix-turn-helix (HTH) DNA-binding output domain, including Bacillus subtilis uncharacterized transcriptional regulatory protein YesN and Staphylococcus aureus uncharacterized response regulatory protein SAR0214. YesN is a member of the two-component regulatory system YesM/YesN and SAR0214 is a member of the probable two-component regulatory system SAR0215/SAR0214. Also included in this family is the AlgR-like group of LytTR/AlgR family response, which includes Pseudomonas aeruginosa positive alginate biosynthesis regulatory protein AlgR and Bacillus subtilis sensory transduction protein LytT, among others. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.34761e-29
NC_014632.1\|WP_083789061.1\|351382_351676_-\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00168923
NC_014632.1\|WP_013386767.1\|355310_355532_+\|ferrous-iron-transport-protein-A	gnl\|CDD\|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	4.74528e-17
NC_014632.1\|WP_013386775.1\|361066_362185_+\|hypothetical-protein	gnl\|CDD\|367900	pfam04303, PrpF, PrpF protein. PrpF is a protein found in the 2-methylcitrate pathway. It is structurally similar to DAP epimerase and proline racemase. This protein is likely to acts to isomerise trans-aconitate to cis-aconitate.	6.15341e-151
NC_014632.1\|WP_013386776.1\|362233_363229_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	5.4023e-83
NC_014632.1\|WP_013386764.1\|353430_354246_+\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	2.66555e-129
NC_014632.1\|WP_013386770.1\|358092_358380_+\|DUF2325-domain-containing-protein	gnl\|CDD\|378383	pfam10087, DUF2325, Uncharacterized protein conserved in bacteria (DUF2325). Members of this family of hypothetical bacterial proteins have no known function.	8.52734e-20
NC_014632.1\|WP_013386777.1\|363294_363774_+\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	6.38231e-06
NC_014632.1\|WP_041921071.1\|358399_358732_+\|DUF2023-family-protein	gnl\|CDD\|378227	pfam09633, DUF2023, Protein of unknown function (DUF2023). This protein of approx.120 residues consists of three beta strands and five alpha helices, thought to fold into a homo-dimer. It is expressed in bacteria.	8.61121e-53
NC_014632.1\|WP_013386778.1\|363788_365303_+\|tripartite-tricarboxylate-transporter-permease	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	1.44642e-165
NC_014632.1\|WP_013386765.1\|354379_354856_+\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	7.87265e-16
NC_014632.1\|WP_013386769.1\|357802_357964_+\|FeoB-associated-Cys-rich-membrane-protein	gnl\|CDD\|378908	pfam12669, P12, Virus attachment protein p12 family. This family of proteins are related to Virus attachment protein p12 from the African swine fever virus. The family appears to contain an N-terminal signal peptide followed by a short cysteine rich region. The cysteine rich region is extremely variable and it is possible that only the N-terminal region is homologous.	0.00627933
NC_014632.1\|WP_013386768.1\|355565_357779_+\|ferrous-iron-transport-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
NC_014632.1\|WP_013386779.1\|365652_368067_+\|PAS-domain-S-box-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.27956e-34
NC_014632.1\|WP_013386781.1\|369512_370259_+\|peptidoglycan-editing-factor-PgeF	gnl\|CDD\|319354	cd16833, YfiH, protein of unknown function YfiH. This subfamily contains YfiH, a protein of unknown function from Shigella flexneri, E. coli, and many similar proteins which collectively are often called DUF152. The structure of YfiH reveals a distant homology to Rho-activating toxins cytotoxic necrotizing factor 1 (CNF1) as well as chemotaxis protein CheD that stimulates methylation of methyl-accepting chemotaxis proteins (MCPs), all having an invariant Cys-His pair forming a catalytic dyad, and is required by the CNF-1 toxins for deamidation activity.	9.4946e-69
NC_014632.1\|WP_013386766.1\|354998_355223_+\|FeoA-domain-containing-protein	gnl\|CDD\|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	1.82264e-06

>NC_014632.1|WP_041921071.1|358399_358732_+|DUF2023-family-protein
MEVFVHHIYEFEKGLRNLVLHTTEKENLKMIMNKLNNRKINYEIYEIEGNRINIFFGAKECVEVIRSIGKQSLREYTFEEDFILGIMLGYDRRKQCERYLSFKEKNARTA
>NC_014632.1|WP_013386770.1|358092_358380_+|DUF2325-domain-containing-protein
MIAIIGGIKGIEREYKNLMDEYNLRCRIYNKTCPSFQKKIKNCEACILFTNTVSHKLSLSCTKICKKNNIKLIRVHSSSLNKLKESLCEICKGCS
>NC_014632.1|WP_013386769.1|357802_357964_+|FeoB-associated-Cys-rich-membrane-protein
MKTIIVIGVVAVIAFFSLRSVIKMLKGENGCGCSKDNNCAMKDHCSSKNKNKK
>NC_014632.1|WP_013386768.1|355565_357779_+|ferrous-iron-transport-protein-B
MIKIAFAGNPNVGKSALINSIAGSKLKVGNWPGVTVEKKEAEFEFEGKKIKMIDLPGVYSLSPYTIEEKITRDYILNENPDVVINVVDSTNLERNLYLTMLLKELGKPMIMALNFLDEFENLNYKLDLKKFQTHLEMEAIHTSAVKNKGIKELLEKALLVAEKHRKQSHIKYELRFDNTIENEIQNIRCKIKEDEKFVPVLQKYAEDFVCIKLLEQDSYFAEILEREYGIEIDSVTKENVDRVEKKFDEDAETVIAEGRYGALKGILAQTFTTSLKSRLDFTDKVDKILLNKYLGLPIFFFIISGIMGVVFNGSGPFIDWVDGFIGGYIGKYVAIAVEGTPDWLYSLVTDGIIGGVGGVLVFVPLMLFLYFFLALLEESGYMSRVAFLMDKIMRRLGLNGKAFVPMVLGFGCTVPAIYATRTLEDEPSRRLTALMAPFMSCGARLPVYGLFTAAFFGARAGMIVMSLYVMGIVVAVLTGMFFKNNPRFKAEDKALLLELPPYRVPSFKMIWSSTMTRTGSYLKKATTVILGILILLWGLIYFPNNGDASNSYMAKFGKVIAPIMKPTGFGNRWEAVAAIAPSIAAKEVVVGFMAQVLPQEKEAISVSEGEIQEETTTFAQDTMEQLRGFAVASKESVISMVSFDVASLFTPPSADEVEDEGAGVVGATAKLWEGDPLGPLRAYSFMVFILLVVPCVVTLAAIKQEFGQKFMWFTVMVMLIVPYIASTVIFQIGRLFI
>NC_014632.1|WP_013386767.1|355310_355532_+|ferrous-iron-transport-protein-A
MKLTDLKRGEKAKIVKIGKIGDLKKRLVDMGVTSGEIIKLERDAPLGDPQQYIIKGTGIAIRKEDAKNIEVER
>NC_014632.1|WP_013386766.1|354998_355223_+|FeoA-domain-containing-protein
MSHPVTYGQLNKKFVIKGINGNDKTKARLIERGFCIGENLCILKDTDENLIIEVNKSRYVVNFGLANKIIVDEA
>NC_014632.1|WP_013386765.1|354379_354856_+|cyclic-nucleotide-binding-domain-containing-protein
MSEKQLEDKIIELLPKTSLFGGVDLKEIHFFVESLVEKRCKAGEIILKEGESPGDSYLLLEGEVKLTVRDRRVDKFGPGTVFGIDSTIGIQKQITTAIAATDIILAIIPKMSLYTLSQKNPDLFSKLILNVARDLARALKGMERIIEDYVLLEEKHLL
>NC_014632.1|WP_013386764.1|353430_354246_+|aldo/keto-reductase
MKKVLLNNGVEVPIIGLGTFRAKGEEVYMAVKTAIDNGYTHIDTAMIYGNEKEINRAIKDSGVKRENLFITTKLWNSDQGYESTKKAFQKSLDDLGLDYIDLYLIHWNKGVEKAAESWKAMEELYKDGKIKAIGVSNFTMYHIEKLLETALVKPAVNQVECHIGLPQYDLQKYCESKGIKLTAYAPMQAGKIFESEELKAIADKHGKSVAHVALKFLVDRGIIVIPKSVKTERIINNKDIFDLELDSEDLKVIKSLWNGKRLYTDPDNCYF
>NC_014632.1|WP_013386763.1|352188_353013_-|nucleoside-specific-channel-forming-protein-Tsx
MKKMFGILFLMVNITSFGSYEPWNYNYTSVSVFQGNNSADGYGESIDDRYVEFEGFHRYNLLDMYWFVDFFDAFDSGSSDVHGQDPNLYGEINPRISLDGLLGKDLSFGNFKEWFISYQYDFDDSSYGGGLKRHQIGIGNDVYIKGFDYVRMNLLARYHKEAYDGSIEDKWDGYLLNAAYGRKLHTFKNGWNIYFSGWVDYVFGANESKDKTDWSGNNIGTDHSLQWFNQLKLQMKYIDLSYSYKINDSFTEVKKSSYNSSDSNQHILGVHYVF
>NC_014632.1|WP_083789061.1|351382_351676_-|transposase
MMEEKRRYARFSEEKQKQIAELSFLKIKTKVELSNEYGITTNTVAAWEKKYFGGPKKDMELSAQDKEIIRLKNLLKEKEEDIEILKKATAIFSRKKR
>NC_014632.1|WP_148223652.1|359885_360668_+|hypothetical-protein
MNRVLIKLDNQEEVKHLAKYANMIKKNYPEAEIVGIFIHPSIGEHSFREFRGVGGDYDIGEAKSEHKAKIEKIMEDENKIREEFLSLVENSSFYAKIGDIPEVLMDELRLFDLAVISKTDKIGHDLREIFKNHNKPIILVPELENYSLDRILVADDQGLEVNKSVFKFMGVFEKTREFKAVTVGVSQEEVKDLNFYLEKIDKKIDYKFEEGAVDKIILNYAKDCDMLIMGNLKRSFMVEKLIGTGGIRALEEVKKPIFIG
>NC_014632.1|WP_013386775.1|361066_362185_+|hypothetical-protein
MRKFPCTILRSGTSKGVFFNEKDMPKDKEKWEDFLLDVMGSPDKKQIDGLGGANSLTSKVAIIKKSEREGFDVDYTFAQVSLTARKIDMKGNCGNISSGVGPFAIDNGLVEAIEPTTKVRIYNTNTGKTIESEVKVSNGMYDPDGDTKIPGVPNTGSVGYLSFYAPEGSVTGKLLPTGKAVDTIETSVGTIDISIVDAANPLVFIKAEDVGLKGTELHYEFSQEKLDLLEEIRSIAAELCGFAKKEDATKNSPAVPKTTVISAPQDYKDEPGTLYRSDEMDLVIRMMSMQKPHQALAITGAVCTSLAAATEGTLVSKIASPDENGKLRLGHPGGVMNAYSGKGDNEDVYVKVERTARRIMEGIVYTRGDYEI
>NC_014632.1|WP_013386776.1|362233_363229_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKRIALLVVGIITALAMVGCGGQPGGKDGGDTAAYPKKPIEMIIPFGEGGASDTFARKFADIMAKDMPQPIQAINKKGSSGLVGMVYAAQKKNDGYTILEVTPSMVIADALEVSESIKFMKDFEPLARIQSDIYVLCLPGDSRFSSFQELVEYGQNNPVTFAGVSPGGLDDLTLNALADATGVDIKFIPYKSGSEVKAAVLGGEVDIYLDKIVSAVNYIKDGKVKPVVVLNEERIDKIDVFKSVPTTVELGYDVTIGSWRGFVVKNGTPQEIKDYLIDKMEKAYATQEYQDFAALNLVDIRPGYLDAEGFYKQWESEYEKFDAVAKKVGLK
>NC_014632.1|WP_013386777.1|363294_363774_+|tripartite-tricarboxylate-transporter-TctB-family-protein
MGEIIFHIFLLVVMGAFYKQSLDINTARMTDPIGPAGFPKTIIYVAVILIVISLVSNIKNYKANKPKEKEKIKELDPGFLALLGIIVFFVLAVNYIGFWFGGIIIISSTMWILNQRKISKLVIITLVGSLVFTFVFGKILSIPLPRGYGIFETISYYIY
>NC_014632.1|WP_013386778.1|363788_365303_+|tripartite-tricarboxylate-transporter-permease
MDTSLLIEALKTIFMPTNFLLVLAGMTLGVFFGALPGISSSMGIVLMIPFTYYMGIIPSIVLLVALYAGSAYGGSITAILFNTPGTAESVATTFDGYPMAQQGKAGKALGLAMSGSAIGGIFSVLVMLLLAPLLSKIALKIQSAEYFALTLLGIACISSVGSKNLSKALVTGLLGIIIAMVGMDPMTGVSRLTFGQINFLNGIEYIPIMIGSFAMAEVFKQVINRKSEEKTMDMGDSVSMESIKLKDLLVYKVTIIKSAIIGTAVGILPGTGGSIASIVSYGEAARSRKDKARFGNGAEEGVLAPETANNAAGGGAMIPTLVLGIPGSPTTAIILAALVLQGLQPGPQLMTEQPLLLYCIFFSMLIASTVVFLSGRYAVKAFAAVLKLPYGIIAPMIVMFSIIGAYARSNDMFQIWVMLTFGVFGYFMKKYQFSAASLILGIVLGNMMEESFRRQLLISNGSYMSFLQRPIAVAIFIAVAFVLFFPIVAGMMEKKKATAAAQNL
>NC_014632.1|WP_013386779.1|365652_368067_+|PAS-domain-S-box-protein
MSFIREIIKYKKSILIFFTGLIFAVSLAFTILKNYKDLRDALVLNEQKHLLTIADTTAKSIESYFLEEERSMRILARDTGFLRDFEYLKDKDERYLGESLKIYYKIGAPRIKSIQLLDFKGIILDEYPTKSKDNISKDISDLKDVKKIIKNKEQVLSSVYFENRDPFIYILQPIFNRGKFQGIIRCKLSIDNIYKRFIENIRSGSKGYASVKTKDGIFLMHPKKSQISGHVMQLRKSKYPNYDWSELEKLFEKQRSGEKGVEIYRSVWVTDDDSKMVKKFNGYSQAYIGDTFWIVTVASDYDEVVKIIKKNYYYTVAIATLIVLSISLLAAYIYSIREKKAKLEMKSLHLNEVKKLNSELEEDIEKRKLLAKELVKSKNKYEAMFNSINDCVFVADFENNSFEDIVEVNEKVYKRLKYTREELLKMKYSDIDVGLSVNEGKKILEKMLDKRSVMYETEIKTKFNKKIPVEVSGRLFKMENKYRAILISRDITLRKIQEETVKRSEARFFNIVNKLASDIEGENSDTTKIKLGKDINNQKILLKLEKINIELEKMFKKEMDENKKKEALMIYQSRYAAMGEMVGNIAHQWRQPLSSLSLIISNIEDSFFYGDVDKEDVESLFKKSRMLINKMSETIDDFRYFFKPKTNKEEFHVKNVVTSTVELFNERMRYNGIECNVETENDVKIWGYPNQLSQVILNFINNAVDALLENREKERKIDILISEEKNSAIVEVQDNGGGIPEGVMEKIFEPYYSTKEKKNGTGIGLYMSQMIVEKNFDGKIYVINKNNGACMKIIIPMGGENENA
>NC_014632.1|WP_013386780.1|368053_368833_+|DUF2294-family-protein
MKMLDKTNLLIKYKVLYVEDDEMQRENLKIFLKRRVGKLYMAENGKEGLKVFEEQNPDIIITDLKMPIMDGIEMSKKIREKNKKSGIVITTAFSDVETVLSAMDVGIDKYILKPVDTGKLIEAMEEIALRLTGEESGNLVLDDKIISDKKEKLEYESKIQIKIAYFIKSNTGKGPKSVKAFIKGSLIEIEANDPLTIYEKKLLEQSKNKSLVNFSREAFYNDRKNEIEKIIFEILGVKGNLERVTIDFKNNRDILVISV
>NC_014632.1|WP_013386781.1|369512_370259_+|peptidoglycan-editing-factor-PgeF
MYVKHNEYFEIEEFENKGIKAIFTGKKSGDVKENFFLSPEKEKNIEEFMKKFSIEGKKLVAAKQTHSKNIADIKDESPLYFDNVDGFITARRDVVLFTVHADCLPIYFYDMEKKVIGLCHSGWKGSYLQIGEEVIKKMKASYGSLEKDILVGIGIGAGKCCYQVGDEFYRDFKEKFPLDVIEASFEKKADSWYFDNGEFNFQMFIKRGILEKNIVKSRQCTVCNRELFSYRREGKDAGRNGAFIYFKD
>NC_014632.1|WP_148223653.1|370218_370710_+|hypothetical-protein
MRDEMVHLSTLKIKVIIFFMIAVTGCSALPEGRKWEDVSFVMYQTDRLKTGDIIVKNKKWDPLSWYGHAAVMIDDMNIGDYPKFGVGYYEIDSYSWLYEERKVMVFRYKNFDEKFKDVFLKNLEGLKDKGYWVPLNKKTPRVFTVHSLYGIFTGKRLRILGII
>NC_014632.1|WP_013386783.1|370836_371268_+|hypothetical-protein
MKKIIFIIFFIFSTALFGRNYTELQEWRQKKLPVDIKKGVRVEVYDFESRHGVKYEYPAINIRVHNRGSSAVTDLVITIWFWKNEGVYVKELVLIGEEGEYRKKLFSGKEKYIPSERRYYNFKDIKFKEIERLEIQITRIKTK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_014632_1	1.1\|359166\|33\|NC_014632\|PILER-CR	359166-359198	33	NC_014632.1	359375-359407	1	0.97

1. spacer 1.1|359166|33|NC_014632|PILER-CR matches to position: 359375-359407, mismatch: 1, identity: 0.97

aatttctgctgcagacggtaaatatgaaatttc	CRISPR spacer
aatttctgctgcagacggtaaatatgagatttc	Protospacer
***************************.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

243354 : 254066

Bacillus_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013386672.1\|243354_245646_+	diguanylate cyclase	G3MA91	Bacillus_virus	7.0e-23	36.1
WP_013386673.1\|245762_246341_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_013386674.1\|246524_248690_+	U32 family peptidase	Q6DW11	Phage_TP	2.4e-25	28.1
WP_013386675.1\|248702_249200_+	phosphatidylglycerophosphatase A	NA	NA	NA	NA
WP_013386676.1\|249218_250427_+	CinA family nicotinamide mononucleotide deamidase-related protein	B5TK85	Pseudomonas_phage	2.0e-16	37.8
WP_013386677.1\|250426_250975_+	cupin domain-containing protein	I3VYY8	Thermoanaerobacterium_phage	5.8e-08	41.1
WP_013386678.1\|251003_251525_+	HAD-IIIA family hydrolase	A0A222YVZ6	Synechococcus_phage	4.5e-10	32.9
WP_013386679.1\|251546_254066_+	DegV family EDD domain-containing protein	A0A0N9SI50	Staphylococcus_phage	2.0e-15	40.4

DBSCAN-SWA_2

473977 : 482421

Orpheovirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013386875.1\|473977_474742_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.9e-13	25.7
WP_013386876.1\|474743_475445_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.6e-13	24.5
WP_013386877.1\|475693_475918_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_013386878.1\|476033_477272_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.3e-79	41.7
WP_013386879.1\|477292_478534_+\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	1.5e-16	25.3
WP_013386880.1\|478568_480344_+\|tRNA	aspartate--tRNA ligase	A0A2K9L3L6	Tupanvirus	1.3e-16	28.0
WP_013386881.1\|480708_482421_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	4.1e-76	34.6

DBSCAN-SWA_3

903529 : 913576

Paramecium_bursaria_Chlorella_virus(12.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013387257.1\|903529_904459_-	GDP-L-fucose synthase	A7IWS0	Paramecium_bursaria_Chlorella_virus	4.3e-96	54.4
WP_013387258.1\|904512_905622_-	GDP-mannose 4,6-dehydratase	A0A0E3I398	Synechococcus_phage	7.3e-127	66.2
WP_013387259.1\|905666_906890_-	WcaI family glycosyltransferase	NA	NA	NA	NA
WP_013387260.1\|907179_908649_+	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	2.4e-56	34.3
WP_013387261.1\|908663_909602_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_013387262.1\|909668_910439_+	glucose-1-phosphate cytidylyltransferase	I7I009	Enterobacteria_phage	3.1e-07	23.6
WP_013387263.1\|910466_911549_+	CDP-glucose 4,6-dehydratase	J7Q7J8	Aeropyrum_coil-shaped_virus	3.0e-16	28.0
WP_013387264.1\|911545_912088_+	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	8.5e-20	37.3
WP_013387265.1\|912107_913004_+	NAD(P)-dependent oxidoreductase	A0A1V0SG19	Hokovirus	7.2e-08	23.5
WP_013387266.1\|913027_913576_+	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	A0A218MN57	uncultured_virus	1.8e-22	34.7

DBSCAN-SWA_4

999191 : 1037308

Lactococcus_phage(28.57%)

integrase,bacteriocin,transposase

attL 1027898:1027957|attR 1037390:1038135

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_083789061.1\|999191_999485_+\|transposase	transposase	NA	NA	NA	NA
WP_148223647.1\|999463_1000369_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	4.7e-39	37.5
WP_013387355.1\|1000372_1000774_-	hypothetical protein	NA	NA	NA	NA
WP_013387356.1\|1001169_1001397_-	hypothetical protein	NA	NA	NA	NA
WP_013387357.1\|1001396_1001882_-	hypothetical protein	NA	NA	NA	NA
WP_013387358.1\|1002126_1003890_+	DUF2779 domain-containing protein	NA	NA	NA	NA
WP_013387359.1\|1004273_1005263_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013387360.1\|1008172_1009675_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.9e-17	36.1
WP_013387361.1\|1011229_1011919_+	DUF4393 domain-containing protein	NA	NA	NA	NA
WP_013387362.1\|1011959_1013288_+	hypothetical protein	NA	NA	NA	NA
WP_013387363.1\|1013342_1014722_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_013387364.1\|1015183_1015522_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_013387365.1\|1015576_1016878_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	3.9e-71	41.0
WP_013387366.1\|1016936_1017275_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_013387367.1\|1017312_1017489_+	hypothetical protein	NA	NA	NA	NA
WP_013387368.1\|1017657_1018830_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_013387369.1\|1018872_1019646_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_013387370.1\|1019669_1019891_-	hypothetical protein	NA	NA	NA	NA
WP_013387371.1\|1020038_1020764_+	putative selenium-dependent hydroxylase accessory protein YqeC	NA	NA	NA	NA
WP_013387372.1\|1020901_1022518_-	nitrite/sulfite reductase	NA	NA	NA	NA
WP_013387373.1\|1022840_1023002_+	hypothetical protein	NA	NA	NA	NA
WP_013387374.1\|1023388_1023811_+	hypothetical protein	NA	NA	NA	NA
WP_013387375.1\|1023935_1024556_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_013387376.1\|1024637_1025666_-	potassium channel protein	NA	NA	NA	NA
WP_013387377.1\|1025870_1026233_+	hypothetical protein	NA	NA	NA	NA
WP_013387378.1\|1026249_1027035_+\|bacteriocin	bacteriocin family protein	NA	NA	NA	NA
WP_013387379.1\|1027113_1027443_+	hypothetical protein	NA	NA	NA	NA
WP_013387380.1\|1027532_1027862_+	hypothetical protein	NA	NA	NA	NA
1027898:1027957	attL	NA	NA	NA	NA
WP_013387381.1\|1028038_1028506_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	2.3e-18	36.9
WP_013387382.1\|1029491_1029788_+	hypothetical protein	NA	NA	NA	NA
WP_013387383.1\|1029917_1030892_-\|integrase	site-specific integrase	A0A0A8WIE1	Clostridium_phage	8.4e-10	28.4
WP_013387384.1\|1030948_1031392_-	hypothetical protein	NA	NA	NA	NA
WP_013387385.1\|1031402_1032083_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_013387386.1\|1032120_1032942_-	M23 family metallopeptidase	A0A292GJG6	Xanthomonas_phage	2.9e-27	52.5
WP_013387387.1\|1033073_1033616_+	hypothetical protein	NA	NA	NA	NA
WP_187288113.1\|1033654_1034452_-	VIT1/CCC1 transporter family protein	NA	NA	NA	NA
WP_013387389.1\|1034572_1036636_-	glycogen-debranching protein	NA	NA	NA	NA
WP_013387381.1\|1036840_1037308_-\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	2.3e-18	36.9
1037390:1038135	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1116321 : 1177208

Fusobacterium_phage(26.09%)

protease,terminase,plate,capsid,tail,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013387468.1\|1116321_1116855_-	N-acetylmuramoyl-L-alanine amidase	A0A2I7R243	Vibrio_phage	1.3e-20	39.0
WP_013387469.1\|1116863_1117442_-	hypothetical protein	NA	NA	NA	NA
WP_013387470.1\|1117441_1118548_-	hypothetical protein	NA	NA	NA	NA
WP_013387471.1\|1118540_1119146_-\|tail	phage tail protein I	A0A2K9V471	Faecalibacterium_phage	1.7e-13	28.0
WP_013387472.1\|1119138_1120236_-\|plate	baseplate J/gp47 family protein	A0A0C5AEG2	Bacteriophage	5.1e-72	39.6
WP_013387473.1\|1120228_1120528_-	hypothetical protein	NA	NA	NA	NA
WP_013387474.1\|1120530_1121034_-\|tail	phage tail protein	NA	NA	NA	NA
WP_013387475.1\|1121149_1121689_-\|plate	phage baseplate assembly protein V	A0A067ZIM2	Vibrio_phage	1.5e-16	39.3
WP_013387476.1\|1121688_1122723_-	late control D family protein	A0A067ZG47	Vibrio_phage	3.7e-32	28.2
WP_148223697.1\|1122724_1122922_-\|tail	tail protein X	A0A0C5AEF4	Bacteriophage	4.9e-10	46.2
WP_013387478.1\|1122926_1125308_-\|tail	phage tail tape measure protein	Q8HAC2	Salmonella_phage	4.0e-37	27.9
WP_013387479.1\|1125443_1125782_-	hypothetical protein	NA	NA	NA	NA
WP_013387480.1\|1125807_1126494_-	Rha family transcriptional regulator	A0A1W6JPM7	Staphylococcus_phage	4.6e-47	46.8
WP_013387481.1\|1126506_1127025_-\|tail	phage major tail tube protein	A0A067ZJA9	Vibrio_phage	4.7e-28	38.6
WP_013387482.1\|1127024_1128461_-	hypothetical protein	A0A0E3U251	Fusobacterium_phage	1.5e-100	39.5
WP_013387483.1\|1128465_1128768_-	hypothetical protein	NA	NA	NA	NA
WP_013387484.1\|1128777_1129257_-	hypothetical protein	NA	NA	NA	NA
WP_013387485.1\|1129256_1129817_-\|tail	phage tail protein	NA	NA	NA	NA
WP_013387486.1\|1129813_1130143_-	hypothetical protein	NA	NA	NA	NA
WP_013387487.1\|1130129_1130462_-	hypothetical protein	NA	NA	NA	NA
WP_013387488.1\|1130468_1131506_-\|capsid	major capsid protein	A0A059WRQ2	Vibrio_phage	3.5e-30	25.1
WP_013387489.1\|1131516_1131843_-	hypothetical protein	NA	NA	NA	NA
WP_013387490.1\|1131844_1132927_-\|protease	Clp protease ClpP	A0A0E3Y6E9	Fusobacterium_phage	2.7e-57	38.6
WP_013387491.1\|1132913_1134455_-\|portal	phage portal protein	A0A0E3Y693	Fusobacterium_phage	6.2e-124	45.9
WP_013387492.1\|1134463_1134685_-	hypothetical protein	A0A0C5AEE0	Bacteriophage	2.3e-08	46.7
WP_013387493.1\|1134685_1136497_-\|terminase	phage terminase large subunit family protein	A0A0E3U2N4	Fusobacterium_phage	2.8e-168	52.2
WP_013387494.1\|1136468_1136948_-	hypothetical protein	A0A0E3Y4U4	Fusobacterium_phage	2.8e-14	30.4
WP_013387495.1\|1137070_1137577_-	hypothetical protein	NA	NA	NA	NA
WP_013387496.1\|1137746_1138769_-	hypothetical protein	NA	NA	NA	NA
WP_013387497.1\|1138769_1140026_-	site-specific DNA-methyltransferase	D0R0C5	Streptococcus_phage	1.1e-99	45.4
WP_013387498.1\|1140222_1140384_-	hypothetical protein	NA	NA	NA	NA
WP_041921162.1\|1140492_1140690_-	hypothetical protein	NA	NA	NA	NA
WP_013387500.1\|1140685_1141330_-	hypothetical protein	NA	NA	NA	NA
WP_013387501.1\|1141334_1142225_-	hypothetical protein	NA	NA	NA	NA
WP_013387502.1\|1142243_1145294_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	5.5e-15	21.9
WP_013387503.1\|1145319_1146621_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_041921163.1\|1146613_1148836_-	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	1.8e-28	31.8
WP_013387505.1\|1149615_1150221_-	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_013387506.1\|1150236_1150917_-	helix-turn-helix domain-containing protein	A0A0E3U270	Fusobacterium_phage	8.9e-43	41.0
WP_013387507.1\|1151058_1151211_+	DNA-binding protein	NA	NA	NA	NA
WP_013387508.1\|1151287_1151773_+	hypothetical protein	NA	NA	NA	NA
WP_013387509.1\|1151748_1152705_+	hypothetical protein	NA	NA	NA	NA
WP_013387510.1\|1152694_1152925_+	hypothetical protein	NA	NA	NA	NA
WP_013387511.1\|1153207_1153348_+	hypothetical protein	NA	NA	NA	NA
WP_013387512.1\|1153366_1153504_+	hypothetical protein	NA	NA	NA	NA
WP_013387513.1\|1153744_1153945_+	hypothetical protein	NA	NA	NA	NA
WP_013387515.1\|1154088_1155498_+	recombinase family protein	NA	NA	NA	NA
WP_013387516.1\|1155572_1155746_-	hypothetical protein	NA	NA	NA	NA
WP_013387517.1\|1155747_1157133_-	hypothetical protein	NA	NA	NA	NA
WP_013387518.1\|1157562_1157772_-	glutaredoxin	NA	NA	NA	NA
WP_013387519.1\|1157824_1158736_-	nucleoside hydrolase	NA	NA	NA	NA
WP_013387520.1\|1158799_1159417_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_013387521.1\|1159431_1160220_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_013387522.1\|1160249_1161191_-	D-2-hydroxyacid dehydrogenase	M1HBE3	Paramecium_bursaria_Chlorella_virus	8.6e-28	31.3
WP_013387523.1\|1161241_1161886_-	hypothetical protein	NA	NA	NA	NA
WP_013387524.1\|1162355_1163093_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_013387525.1\|1163139_1163526_-	HAD hydrolase family protein	A0A1W6DYI0	Aeromonas_phage	9.3e-13	38.7
WP_013387526.1\|1163883_1164966_+	glycerol dehydrogenase	NA	NA	NA	NA
WP_013387527.1\|1164999_1166709_-	hydroxylamine reductase	NA	NA	NA	NA
WP_013387528.1\|1166925_1167123_+	hypothetical protein	NA	NA	NA	NA
WP_013387529.1\|1167160_1167799_-	alpha/beta hydrolase fold protein	NA	NA	NA	NA
WP_013387530.1\|1167809_1168376_-	nicotinate (nicotinamide) nucleotide adenylyltransferase	NA	NA	NA	NA
WP_013387531.1\|1168375_1168822_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_013387532.1\|1168840_1169644_-	hypothetical protein	NA	NA	NA	NA
WP_013387533.1\|1169658_1170648_-	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_013387534.1\|1170665_1172348_-	ABC-ATPase domain-containing protein	NA	NA	NA	NA
WP_013387535.1\|1172357_1175870_-	chromosome segregation protein SMC	NA	NA	NA	NA
WP_013387536.1\|1175885_1177208_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IDZ7	Erwinia_phage	5.2e-31	25.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014633

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_014632

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection