CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016445	Vibrio cholerae O1 str. 2010EL-1786 chromosome 1, complete sequence	0 crisprs	WYL,DinG,csa3,DEDDh,cas3,csx1,RT	0	0	5	0
NC_016446	Vibrio cholerae O1 str. 2010EL-1786 chromosome 2, complete sequence	0 crisprs	csa3,cas3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

51695 : 123671

uncultured_virus(27.27%)

tRNA,protease,transposase,integrase

attL 45711:45726|attR 107052:107067

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
45711:45726	attL	NA	NA	NA	NA
WP_000146472.1\|51695_52883_+\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
WP_000898882.1\|52950_54396_-	serine-type D-Ala-D-Ala carboxypeptidase	NA	NA	NA	NA
WP_001044323.1\|54493_55519_-	porin OmpU	NA	NA	NA	NA
WP_001883448.1\|56073_56547_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_001054291.1\|56623_56920_-	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
WP_000043220.1\|57039_57669_+	23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE	NA	NA	NA	NA
WP_001107450.1\|57778_59725_+\|protease	ATP-dependent zinc metalloprotease FtsH	A0A0P0BXI2	Ostreococcus_lucimarinus_virus	2.3e-120	44.4
WP_000913082.1\|59791_60628_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	3.2e-18	32.6
WP_001281065.1\|60653_61994_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_000495557.1\|62250_62586_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_000147148.1\|63016_63472_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_000031601.1\|63490_64978_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_000192207.1\|65002_67699_+	translation initiation factor IF-2	NA	NA	NA	NA
WP_001123656.1\|67800_68199_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_000124044.1\|68198_69137_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_000055654.1\|69278_69548_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_000462070.1\|69910_72040_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_001883460.1\|72155_73067_+	lipoprotein NlpI	NA	NA	NA	NA
WP_000887847.1\|73165_73573_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000981941.1\|73619_74957_+	sodium-coupled multidrug efflux MATE transporter VcrM	NA	NA	NA	NA
WP_000872504.1\|75009_75888_-	U32 family peptidase	NA	NA	NA	NA
WP_000421327.1\|75899_76913_-	U32 family peptidase	NA	NA	NA	NA
WP_001111411.1\|77020_79075_-	bifunctional diguanylate cyclase/phosphodiesterase	NA	NA	NA	NA
WP_000932672.1\|79307_79835_+	SCP2 domain-containing protein	NA	NA	NA	NA
WP_000908540.1\|79818_80322_+	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	1.7e-19	32.2
WP_000953212.1\|80432_80840_+	DNA polymerase III subunit psi	NA	NA	NA	NA
WP_000214238.1\|80836_81286_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_000160066.1\|81274_83332_-	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	6.9e-14	34.3
WP_001910883.1\|83535_83634_+	hypothetical protein	NA	NA	NA	NA
WP_000127615.1\|84072_84261_+	hypothetical protein	NA	NA	NA	NA
WP_000211147.1\|84406_86425_+	ATP-binding protein	NA	NA	NA	NA
WP_001218618.1\|86554_87796_-\|integrase	integrase family protein	A0A291AWU1	Escherichia_phage	1.3e-76	39.8
WP_001995600.1\|87797_88067_-	hypothetical protein	NA	NA	NA	NA
WP_000497807.1\|88069_89044_-	ParM/StbA family protein	NA	NA	NA	NA
WP_000348524.1\|89508_89952_+	hypothetical protein	NA	NA	NA	NA
WP_000985631.1\|92125_95104_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_001120888.1\|95521_97015_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_001447541.1\|97045_97930_+	DUF3363 domain-containing protein	NA	NA	NA	NA
WP_000214119.1\|98146_99361_+	chloramphenicol/florfenicol efflux MFS transporter FloR	S4TR35	Salmonella_phage	4.2e-19	28.7
WP_001255015.1\|99388_99694_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000480968.1\|100316_101153_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_001082316.1\|101152_101956_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	Q75ZG1	Hepacivirus	3.8e-24	34.3
WP_001043260.1\|102016_102832_-	sulfonamide-resistant dihydropteroate synthase Sul2	NA	NA	NA	NA
WP_001122813.1\|104646_105858_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.2e-51	51.4
WP_001883756.1\|106571_106841_-	hypothetical protein	A0A218MNF2	uncultured_virus	9.3e-28	76.3
WP_000116661.1\|106848_107298_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A218MND2	uncultured_virus	4.1e-36	57.1
107052:107067	attR	NA	NA	NA	NA
WP_000182836.1\|107296_107554_+	hypothetical protein	NA	NA	NA	NA
WP_000196209.1\|107937_108843_+	DNA polymerase III subunit epsilon	A0A2H4P6W5	Pseudomonas_phage	3.1e-06	26.4
WP_000284114.1\|108930_109230_+	hypothetical protein	NA	NA	NA	NA
WP_000180270.1\|109547_110468_+	WYL domain-containing protein	NA	NA	NA	NA
WP_000653856.1\|110485_111286_+	DUF1819 family protein	NA	NA	NA	NA
WP_001115853.1\|111269_111818_+	hypothetical protein	NA	NA	NA	NA
WP_000152592.1\|111830_115520_+	BREX system P-loop protein BrxC	NA	NA	NA	NA
WP_000779609.1\|115524_119265_+	BREX-1 system adenine-specific DNA-methyltransferase PglX	NA	NA	NA	NA
WP_000567536.1\|119277_121581_+	PglZ domain-containing protein	NA	NA	NA	NA
WP_000279702.1\|121619_123671_+\|protease	protease Lon-related BREX system protein BrxL	NA	NA	NA	NA

DBSCAN-SWA_2

278697 : 285890

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000775253.1\|278697_279912_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
WP_000331703.1\|279948_280332_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_000301571.1\|280392_280716_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_001105747.1\|280764_281280_+	co-chaperone HscB	NA	NA	NA	NA
WP_001196560.1\|281303_283154_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
WP_001124187.1\|283167_283506_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_000872176.1\|283554_283749_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_000107237.1\|283968_285258_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
WP_001162850.1\|285461_285890_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_3

1041237 : 1057901

Vibrio_phage(44.44%)

coat,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000593523.1\|1041237_1041612_-	cholera enterotoxin binding subunit CtxB	B9V4E7	Vibrio_virus	1.0e-64	100.0
WP_001881225.1\|1041608_1042385_-	cholera enterotoxin catalytic subunit CtxA	A0A142I6Y0	Vibrio_phage	1.3e-151	100.0
WP_000021616.1\|1042490_1043690_-	zonula occludens toxin ZOT	A0A142I6Z1	Vibrio_phage	5.3e-240	100.0
WP_000979342.1\|1043686_1043980_-	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	3.7e-46	100.0
WP_001268534.1\|1043976_1045164_-\|coat	minor coat protein pIII	A0A142I701	Vibrio_phage	1.4e-200	100.0
WP_000493022.1\|1045270_1045519_-	colonization factor	A0A0N7F140	Vibrio_phage	8.8e-33	100.0
WP_000842207.1\|1045654_1046011_-	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000743997.1\|1046012_1047092_-	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000693566.1\|1047217_1047556_+	helix-turn-helix transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
WP_000053920.1\|1048067_1048292_-	RstC protein	U5TMI6	Satellite_phage	1.1e-34	100.0
WP_001911551.1\|1048385_1048736_-	hypothetical protein	U5TMH5	Satellite_phage	1.0e-63	100.0
WP_000743997.1\|1048737_1049817_-	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000693566.1\|1049942_1050281_+	helix-turn-helix transcriptional regulator	U5TNA1	Satellite_phage	7.3e-54	100.0
WP_000170634.1\|1050770_1051355_-	DNA-binding protein	E3U9I9	Vibrio_phage	6.4e-114	100.0
WP_001161489.1\|1051347_1051515_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0
WP_001052673.1\|1051592_1052285_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000512956.1\|1052414_1052684_-	hypothetical protein	NA	NA	NA	NA
WP_002003155.1\|1052703_1054269_-	replication protein	A7BJY2	Enterobacteria_phage	3.9e-57	32.3
WP_000005769.1\|1054445_1054997_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_156991674.1\|1055341_1056527_+\|transposase	IS3-like element ISVch4 family transposase	Q716C2	Shigella_phage	1.5e-117	65.1
WP_001122813.1\|1056689_1057901_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.2e-51	51.4

DBSCAN-SWA_4

1892933 : 1899550

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864130.1\|1892933_1893404_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
WP_001122865.1\|1893668_1894778_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_000493874.1\|1894818_1895472_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001131994.1\|1895476_1896580_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
WP_000543544.1\|1896605_1897055_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_000366574.1\|1897154_1898405_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
WP_000210573.1\|1898416_1899550_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

DBSCAN-SWA_5

2973389 : 2980613

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000698379.1\|2973389_2974142_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.0e-69	53.3
WP_000002982.1\|2974134_2974761_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_000177568.1\|2974760_2975696_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000116737.1\|2975769_2976777_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_001894770.1\|2976869_2979458_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
WP_001279365.1\|2979725_2980613_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage