CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	4 crisprs	DEDDh,c2c10_CAS-V-U3,cas14j,WYL	2	16	2
NC_014825	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence	1 crisprs	csa3,DEDDh	0	1	1
NC_014833	Ruminococcus albus 7 = DSM 20455, complete sequence	8 crisprs	c2c10_CAS-V-U3,csa3,WYL,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,DEDDh	0	9	6
NC_014827	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL04, complete sequence	0 crisprs	NA	0	0	0
NC_014826	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL03, complete sequence	0 crisprs	NA	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_014824_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014824_1

93995-94579

TypeV

Consensus_repeat	Method
ACACTTGATGTAAGCGGATTTGATACAAGCAAAGTAACCGATATG	CRISPRCasFinder

7 spacers

c2c10_CAS-V-U3,cas14j

The CRISPR arrays of NC_014824_1

>merge|NC_014824|1|93995-94579|CRISPRCasFinder
TCGCTCAATTTAAGTGGATTTGATACAAGCAATGTTACTGATATGAGCTATATGTTCAACGAGTGTGGCAAACTTTATTCTATCGATGTAAGCGGATTTGATACAAGCAACGTTACAGATATGGGTGATATGTTCTCTCTTTGTGACCAATTAACATCGCTTGATGTAAGCAGATTTAACACAAGCAAAGTTACAGATATGAGTGGTATGTTCAATTCCTGTCTTAGCTTGTCAACGCTTGATGTTAGCGGTTTTGACACAAGCAATGTTACAGATATGTGTGATATGTTCTGGGGCTGTGCAAAATTGACGTCACTTGATATTAGCAAATTTGACACAAGCAAAGTTACAAATATGGGTGGTATGTTCTGTGCCTGTAATAAATTGACTACACTTGATGTAAGCGGATTTGATACAAGCAAAGTAACCGATATGTCAGGAATGTTCGCTTCAACTAACTTATCAACACTTGATGTAAGCGGATTTGATACAAGCAAAGTAACCGATATGATGGCAATGTTCTCTTCAAGAAATTTGACCGAACTTGATCTGAGCTCGTTTGATACAAGCAAAGTTACAAAGATG

>NC_014824|1|1|93995-94579|CRISPRCasFinder
TCGCTCAATTTAAGTGGATTTGATACAAGCAATGTTACTGATATG	AGCTATATGTTCAACGAGTGTGGCAAACTTTAT
TCTATCGATGTAAGCGGATTTGATACAAGCAACGTTACAGATATG	GGTGATATGTTCTCTCTTTGTGACCAATTAACA
TCGCTTGATGTAAGCAGATTTAACACAAGCAAAGTTACAGATATG	AGTGGTATGTTCAATTCCTGTCTTAGCTTGTCA
ACGCTTGATGTTAGCGGTTTTGACACAAGCAATGTTACAGATATG	TGTGATATGTTCTGGGGCTGTGCAAAATTGACG
TCACTTGATATTAGCAAATTTGACACAAGCAAAGTTACAAATATG	GGTGGTATGTTCTGTGCCTGTAATAAATTGACT
ACACTTGATGTAAGCGGATTTGATACAAGCAAAGTAACCGATATG	TCAGGAATGTTCGCTTCAACTAACTTATCA
ACACTTGATGTAAGCGGATTTGATACAAGCAAAGTAACCGATATG	ATGGCAATGTTCTCTTCAAGAAATTTGACC
GAACTTGATCTGAGCTCGTTTGATACAAGCAAAGTTACAAAGATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014824.1\|WP_013483369.1\|91098_92625_-\|leucine-rich-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|275383
NC_014824.1\|WP_013483361.1\|81932_82676_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483381.1\|106123_107449_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c10_CAS-V-U3	-	gnl\|CDD\|223747
NC_014824.1\|WP_050793323.1\|92952_93132_-\|transposase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379385
NC_014824.1\|WP_013483371.1\|95183_97859_+\|discoidin-domain-containing-protein	unknown	unknown	gnl\|CDD\|373145
NC_014824.1\|WP_013483372.1\|98337_99507_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379306
NC_014824.1\|WP_013483363.1\|84915_85359_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483367.1\|88448_89567_+\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NC_014824.1\|WP_080557320.1\|90646_90820_-\|DUF434-domain-containing-protein	unknown	unknown	gnl\|CDD\|377270
NC_014824.1\|WP_080557322.1\|105985_106105_+\|transposase	unknown	unknown	gnl\|CDD\|224854
NC_014824.1\|WP_013483366.1\|88009_88441_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483362.1\|82840_84166_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c10_CAS-V-U3	-	gnl\|CDD\|223747
NC_014824.1\|WP_013483375.1\|100647_101094_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483378.1\|103678_104797_+\|transposase	cas14j	-	gnl\|CDD\|223747
NC_014824.1\|WP_013483364.1\|85495_85678_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371573
NC_014824.1\|WP_013483365.1\|86296_86470_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_028504522.1\|101440_101659_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_014824.1\|WP_013483380.1\|105260_105578_-\|protein-tyrosine-phosphatase	unknown	unknown	gnl\|CDD\|226924
NC_014824.1\|WP_013483374.1\|100181_100406_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_014824.1\|WP_013483379.1\|104859_105237_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014824.1\|WP_013483369.1\|91098_92625_-\|leucine-rich-repeat-domain-containing-protein	gnl\|CDD\|275383	sd00036, LRR_3, leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	2.68094e-48
NC_014824.1\|WP_013483381.1\|106123_107449_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000206529
NC_014824.1\|WP_013483380.1\|105260_105578_-\|protein-tyrosine-phosphatase	gnl\|CDD\|226924	COG4551, COG4551, Predicted protein tyrosine phosphatase [General function prediction only].	2.6702e-36
NC_014824.1\|WP_013483371.1\|95183_97859_+\|discoidin-domain-containing-protein	gnl\|CDD\|373145	pfam14587, Glyco_hydr_30_2, O-Glycosyl hydrolase family 30.	5.48562e-19
NC_014824.1\|WP_013483372.1\|98337_99507_+\|ATP-binding-protein	gnl\|CDD\|379306	pfam13635, DUF4143, Domain of unknown function (DUF4143). This domain is almost always found C-terminal to an ATPase core family.	4.43042e-46
NC_014824.1\|WP_050793323.1\|92952_93132_-\|transposase-domain-containing-protein	gnl\|CDD\|379385	pfam13817, DDE_Tnp_IS66_C, IS66 C-terminal element.	2.82264e-05
NC_014824.1\|WP_013483367.1\|88448_89567_+\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	1.2477e-09
NC_014824.1\|WP_080557320.1\|90646_90820_-\|DUF434-domain-containing-protein	gnl\|CDD\|377270	pfam04256, DUF434, Protein of unknown function (DUF434).	2.73805e-17
NC_014824.1\|WP_080557322.1\|105985_106105_+\|transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000343716
NC_014824.1\|WP_013483374.1\|100181_100406_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	6.77865e-10
NC_014824.1\|WP_013483362.1\|82840_84166_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00402625
NC_014824.1\|WP_013483378.1\|103678_104797_+\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.37122e-56
NC_014824.1\|WP_013483364.1\|85495_85678_-\|hypothetical-protein	gnl\|CDD\|371573	pfam11515, Cul7, Mouse development and cellular proliferation protein Cullin-7. The Cullin Ring Ligase family member, Cul7, is required for normal mouse development and cellular proliferation. Cul7 has a CPH domain which is a p53 interaction domain. The CPH domain interaction surface of P53 is present in the tetramerisation domain.	0.00566742
NC_014824.1\|WP_028504522.1\|101440_101659_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.49198e-08

>NC_014824.1|WP_050793323.1|92952_93132_-|transposase-domain-containing-protein
MSIIETAKRNELDVYGYMLYLLTVLPKWGADPTETQLKSVMPWSMALPSYCKQTYSEVK
>NC_014824.1|WP_013483369.1|91098_92625_-|leucine-rich-repeat-domain-containing-protein
MKKQIICGLAAAVLTASMGGTALGNAVIMHSEITASAATIAEQGTCGEKLTWKLDSEGTLTISGSGNMDDYTVASWEKVKAPWYPFKDDIKKVVISKGTESIGERAFINCNNITSVTIPTGVKSIGIDAIRNCKSLTSITIPYGVTAISTRAFQNCSGLKSITLPDSITDIGTDAFFGCTNLTDINIPDSVTSIGVHAFKNCTSLSGITIPDSVTKIGGGAFDCCRNLISANIPDGITAINDCTFQDCRSLKSITIPDSVKTIGSDAFYGCNSLLNVTIPASVTSIGQKAFGYYYAIGFDEIKIKELKIYCYPDSEGEKYAKKYNVQYEYIGNKNKTDITFVPGAGYAELSWKADKNAEKYAIAVYQNDKWKLVEKTTDNSYTLRGLNFISKYRVAVFAMYNGKWDMNFSNPVLVVIDEWQPSETWSVYSPTTHQYSFGWERIKNATEYGIAVKIANKWKVVEYTEKTSYTTPRLTPGDKYKVVICAKINGKWDTRDLDKRSFTITIK
>NC_014824.1|WP_080557320.1|90646_90820_-|DUF434-domain-containing-protein
MHKAAEEVYFLLNRGYPVTSTTRFIGDHYQLSERQRLALARTIDLALCGVFSFIRKK
>NC_014824.1|WP_013483367.1|88448_89567_+|ISAs1-family-transposase
MNNGITEYFEDIELYEEYDGYFCSIPDIITIAILGSICGLRNIHQIHQWATNDRVSEFLKEKFGIDHVPCYYWILSLLKYVKPESLNRCFADWVYSFMPEKSKSMTISLDGKTVCSTLKMSKIESPLHIISAQICELGLTLAQRSTDDKSNEIPAVQELLKELKIKGNIVVADALNCQKETAEIIVKQKADYLLCVKDNHPNLKKDIEDYVQDSSLRDTMQTVSRTEKNRGRVETRTAYVTTDINWLEQKKEWKNLKCIGAIHTEFSTKKGTSSEWHYYLSSREMTAEQLLHHARMEWSVESMHWLLDVHFEEDWCRVENKDVQQCLNMFRKAAINLIKNFKNRNNSKAAISKLMFECLMEPQMISRVIFEN
>NC_014824.1|WP_013483366.1|88009_88441_+|hypothetical-protein
MALKGIHGGRFSFDSKELIKEIKRDIVEFGREEIYAVWLRKYPQYNVEFIVNYDFIIDEDDDPFKDFEVNDDYLYGKFEKGENERIVLMSADKILDYLQKQNDPTEIYEVNVHGNQFSKNQVSKVTFIFQVVQITGQSTWKMI
>NC_014824.1|WP_013483365.1|86296_86470_+|hypothetical-protein
MSYEIYRITARCKCPCGKGEIIRGDSMNDWNQTRSGDIEIHCPECSNKLKFTDGGIN
>NC_014824.1|WP_013483364.1|85495_85678_-|hypothetical-protein
MSRVTVGEKVKILEDYLDIRKGSVATIIYIDDFDQVTVSWHSGGQSSFPEEYLYKMFAVA
>NC_014824.1|WP_013483363.1|84915_85359_-|hypothetical-protein
MNTTLREFICNIETIKAKNTEIDFYQDGLSGNKLHELRISKKASERTLLDISRLTEAQKDGLAKCGTLCWCCQHSTDLECRWFQNFRPVPGWVAIPERCMNAISYMVFDCPNFLRTSRFAAEKEQYKEPITYKVDIADDVLVGNIRI
>NC_014824.1|WP_013483362.1|82840_84166_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MQIYTTYSVKIKHYNNIFKDTVIEYRHAVDYLIKVCLDKWDNIITFKGVSRLTYIETLIHTTKDNPDPIYDFDAKFYKMPSYLRRGAINEAIGKVSSYKTNLDNWIKDPVGREPSYPKAGYSFPSMYRTVMYNRTGDYTAQIKVYIRNTWDWITINLKKSDMDYIYRYCSFRKQCAPTLQKRGKEWFLDFPFEEKVKLADISVYEQTIVAVDLGINTAATISVMRSDGTILGRHFCKLTKETDHLMHCVNRIKKAQQHGNYKTPRLWAKAKGINHDIATKTANCIVDIAVLYNADVIVFEHLDKNGKVRGSKKQKLKLWRSQEVQSIVTNKAHRLGMRVSHICAWNTSRLAYDGSGFVLRGKFGGFNTYELCKFQNGKTYNCDLSASYNIGARYFIREILKSLDENSRLLIEAKVPQFSKRSTCTFSTLVNLNAEIIAKTA
>NC_014824.1|WP_013483361.1|81932_82676_-|hypothetical-protein
MIITDKQKMAIILEYEEILVGKRRQASTYYFGDNADRNNSIAVEIFRYLIENILGWDPETAEQRLDLEILKNYKVDKYLSYINFYNEPNGKARFYTSEENGEAHKKMVKSDIQVLLKYVFGSRYHLDEREMIIVTYNDLLNGVIKKFPKHFFDVINDGKLKVAICLQHAITQQQNFENIEDVYRLFGDRNILKWLDKWKLRDIAEQFYDSPIDFLHDALPETEKDEVFYNYYKRQYEEFISESGRKF
>NC_014824.1|WP_013483371.1|95183_97859_+|discoidin-domain-containing-protein
MKIFKRLTALFCTGGMLLMSAPHCVLTSHAAQTVKLSPDNTFTINNGEFEGWGTSLCWWANRLGYSDSLAQQAADVFYGDEGLRLNIARFNIGGGDDPSHNHITRTDSNMPGYTKYSNGKITYDWSADANQRNVLMRSIQAAGDDMIVEMFSNSPPYYMTKSGCSSGSADAKSNNLKDDQYDDFARYFAEVCYHYQHDWGVKIQSAEAMNEPYTNFWKANSYKQEGCHFDQGSSQSTMIVELQKAMRDKGMGDVILCGTDETSIDTQISSFNKLSNDAKKAIGRIDTHTYGGSKRAELKNIALSNGKNLWMSEVDSSGTAGTNAGEMSAALWLAQRITTDVNDMNASAWIMWQVIDSHISKNGYNGRKDTGMVDTQKGYWGVAVANHDANKIVLTKKYYAFGQYSRYIRPGMIMLNSSGNTVAAYDPETGQIVAVSYNTSGSSADITFDLSDFAEVGSTANAIRTSKNENWKNVGTINLNGKTLNATLPGNSITTFVIEGNGSIGGNEIKVQADKLSGSDSWKQNADTDFHKAFDGDNATYFDGTRVGWVQADLGAVYDLSALAYCPRQNYEYRMVDGYFEVSMDGTDWQSIHTISENPTFAMHKVKLEKPITARYIRYAVPEGKPRNSYNTNDVYCCNVAEIKLYGTLNPETSFTKLAPEATSGTDSWKQQEGYNYGKAFDGDTATYFDGVGAGWVQAGLGKICELNAIAYTPRKGYEARMVDGYFSVSEDGTSWQTVHTIGRMPTSDTQTVMLDASVKARYIRYAVPEGKPNNGVNTDDVYCCNIAELAFYGAVLPNAVISNTIKVEYSEKYHQVRFTWDKVEGADRYGIAVYLAGKWRVQAQNITGTVYTSPKNLTPGKKYRVAIAARVNGKWDTANAIKHSGTVTIR
>NC_014824.1|WP_013483372.1|98337_99507_+|ATP-binding-protein
MLNRIAQKALLRLAEQFPIVGITGPRQSGKSTLTKITFPDKKYVTFDDKNMRELAKSNPADFIMAFPNGAVIDEAQKVPEIFDALKLHVDSAPFTPGKFILTGSSQFRLRKNMSDSLAGRAAFLKLLPFSIKELKDADLLPKNAYDLIFVGQYPPLFDSEKHYIAEDWFESYIDTYLDLDVKDQINESNLSTFRKFIQICAIYSGQLLSMDSIAKQIGISQPTVKSWLSILENSYIIHLLEPDTNNLGRSIVKTPKLYFVDSGLLCHLLRLESKEDLLLSKYKGAVVETCAVAEMLKNRMNQAKKPNLTFYRDSNGFEVDTIADWKHTFAVEIKSSSDAEAKLSANTKKYLTLRNDDNAHNAVFYLGDISMTINDTMYVSWKDWGDHLN
>NC_014824.1|WP_013483374.1|100181_100406_+|helix-turn-helix-transcriptional-regulator
MPVIDVKATGANIKAIMKMKGFKIADVQARCGFNTPQAIFKWLRGDAVPTIDNMIIIADMFGVTIDQIVIIKKI
>NC_014824.1|WP_013483375.1|100647_101094_+|hypothetical-protein
MSIDKRTEMILKKESLTIFNQFCSKLPSESLGLLMMYLQKFNDDNPDNGTIVFTKKEYEKKLGNEEISIDEIQDGIPDLLGPVRFKGDIQIMFSMFISINIRKISNEYSIFMTCSDIAKDYIFTDPNVAKYNFIDEIKRRIDELTSIM
>NC_014824.1|WP_028504522.1|101440_101659_+|helix-turn-helix-transcriptional-regulator
MPVINMTATGSNIKTLIKAKGFKVTELQNILVFNTPQSIFKWMRGESIPSIDNLVILAHILNVTIDEIIILN
>NC_014824.1|WP_013483378.1|103678_104797_+|transposase
MANKAFKFRIYPNNEQKVLFAKTFGCVRLVYNYWLYKKIKQYKEYETTLNYNACAKEMAELKKMEKYSFLREVDSVSLQQSLRHLDTAFQNFYKQPKTGFPRFKSKKCKKNSYSTVCINGNIAISNGYLKLPKVGQVKVKQHRNIPNEYVLKSVTVSQTPSGKYYASILYEYENQVQEQELHDFLGLDFSMHELYKDSNGNEPAYPGYYRRAEKKLKREQKKLSLMQKGSKNRDKQRIKVAKMHEKVANQRKDFLHKQSRQIANAYDCVCIEDLNMQAMSQALKFGKSVSDNGWGMFVTFLKYKLEEQGKRLVKIDKFFASSQTCSCCGYINKETKNLAIRAWDCPECGTHHNRDVNAAINIRNEGMRIALA
>NC_014824.1|WP_013483379.1|104859_105237_-|hypothetical-protein
MKVEYYDNNEYGFFIKVAYDDYIAGAESEEELDSLCYAIEVFTSATDSDFIFDRKVYEKILQQLIPDSTVIIRYVDDEYSMSGRSLLIQVKNTNELIPVVYKGDILPRLKRRGLPLTSASSVLVR
>NC_014824.1|WP_013483380.1|105260_105578_-|protein-tyrosine-phosphatase
MKILFLCSQNKRRSLTAEKYFDGYNGHQVRSAGTENNSRVKVTEGLIGWADMIFCMEKKHLRRIKDKYSSSLSNKKVICLNIPDEYGFMDEELIALLDSSVSEYL
>NC_014824.1|WP_080557322.1|105985_106105_+|transposase
MLKKIYYNKYIWKPSYFVATVSDRSLKQVTDYINSQKTK
>NC_014824.1|WP_013483381.1|106123_107449_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MQIYTTYSVKIKHYNNIFKDTVIVYRHAVDYLISVCLDHWDNIVTFKGVSRLTYIETLIHATKDNPDPIYDFDAKFYKMPSYLRRGAINEAIGKVSSYKSNLDNWIKDPVGREPSHPKAGYSFPSMYRTGMYNQTGDYTAQIKVYIRNTWDWITINLKKSDMDYIYRHCRLRKQCAPTLQKRGKEWFLDFPFEEKVKLADISVYEQTIVAVDLGINTAATVSVMRSDGTILGRHFCKLTKETDHLMHSINRIKKAQQHGNYKTPRLWAKAKGINHDIAIKTANCIVNIAVLYNADVIVFEHLDKNGKVRGSKKQKLKLWRSQEVQSIVTNKAHRLGMRVSHICAWNTSRLAYDGSGFVLRGKFGGFNTYELCKFQNGKSYNCNLSASYNIGARYFIREILKSLDENSRLLIEAKVPQCSKRSTCTFSTLVNLNAEIIAQTA

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Crispr_ID: NC_014824_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014824_2

304527-304824

TypeV-U3

Consensus_repeat	Method
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	PILER-CR
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	CRISPRCasFinder
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	CRT

4 spacers

The CRISPR arrays of NC_014824_2

>merge|NC_014824|2|304527-304824|PILER-CR,CRISPRCasFinder,CRT
GATGCAATCTGTACAGGCAGGTAAATTGCGAGCAGCCATATCCTTTATCAGCCGTCCGCCGCATTCGGGGATGCAATCTGTACAGGCAGGTAAATTGCGAGGTGTAAAAGCCGTCAACATAAAAACCACTACTAGATGCAATCTGTACAGGCAGGTAAATTGCGAGAACAGACGTACAGTTTCAAGGGCGATTGAGATAGATGCAATCTGTACAGGCAGGTAAATTGCGAGAAGTCATTTGCAACAGAGATTTTATTAAAGTGGAGGATGCAATCTGTACAGGCAAGTAAATTACAAA

>NC_014824|2|1|304527-304757|PILER-CR
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	CAGCCATATCCTTTATCAGCCGTCCGCCGCATTCGGG
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	GTGTAAAAGCCGTCAACATAAAAACCACTACTA
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	AACAGACGTACAGTTTCAAGGGCGATTGAGATA
GATGCAATCTGTACAGGCAGGTAAATTGCGAG

>NC_014824|2|2|304527-304824|CRISPRCasFinder
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	CAGCCATATCCTTTATCAGCCGTCCGCCGCATTCGGG
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	GTGTAAAAGCCGTCAACATAAAAACCACTACTA
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	AACAGACGTACAGTTTCAAGGGCGATTGAGATA
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	AAGTCATTTGCAACAGAGATTTTATTAAAGTGGAG
GATGCAATCTGTACAGGCAAGTAAATTACAAA

>NC_014824|2|1|304527-304824|CRT
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	CAGCCATATCCTTTATCAGCCGTCCGCCGCATTCGGG
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	GTGTAAAAGCCGTCAACATAAAAACCACTACTA
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	AACAGACGTACAGTTTCAAGGGCGATTGAGATA
GATGCAATCTGTACAGGCAGGTAAATTGCGAG	AAGTCATTTGCAACAGAGATTTTATTAAAGTGGAG
GATGCAATCTGTACAGGCAAGTAAATTACAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014824.1\|WP_013483537.1\|296505_297228_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_050793327.1\|309054_309285_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483551.1\|308528_308801_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483548.1\|306553_307429_+\|IS1595-family-transposase	unknown	unknown	gnl\|CDD\|372298
NC_014824.1\|WP_013483541.1\|300650_301361_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483546.1\|303510_303975_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483543.1\|301861_302200_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483545.1\|303024_303489_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483552.1\|308793_309042_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483544.1\|302359_302896_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483539.1\|298937_299222_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483549.1\|307550_308138_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483555.1\|312389_312881_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483542.1\|301374_301686_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483550.1\|308140_308509_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483538.1\|297762_298551_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483540.1\|299431_300517_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NC_014824.1\|WP_013483547.1\|305151_306264_+\|dockerin-type-I-repeat-containing-protein	unknown	unknown	gnl\|CDD\|271215
NC_014824.1\|WP_013483554.1\|311828_312350_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483553.1\|309602_311552_+\|leucine-rich-repeat-protein	unknown	unknown	gnl\|CDD\|275383

Protein	Function_ID	Function_description	E-value
NC_014824.1\|WP_013483553.1\|309602_311552_+\|leucine-rich-repeat-protein	gnl\|CDD\|275383	sd00036, LRR_3, leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	8.32352e-36
NC_014824.1\|WP_013483548.1\|306553_307429_+\|IS1595-family-transposase	gnl\|CDD\|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	7.81236e-18
NC_014824.1\|WP_013483547.1\|305151_306264_+\|dockerin-type-I-repeat-containing-protein	gnl\|CDD\|271215	cd14256, Dockerin_I, Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.	3.22793e-12
NC_014824.1\|WP_013483540.1\|299431_300517_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	2.6099e-26

>NC_014824.1|WP_013483546.1|303510_303975_+|hypothetical-protein
MLLSSEKGMDISKDEIVVNAYDNGFYYDAGINFTSGMGVTLENIQDLVSYYGQDSEIDHLWNNSSEDIIYTINEKLNEGHRLICGHRTFSGTLHYIVIYGKYCEKNCMYYKIVDPWGGTVYTWDQWTLSDRIMSVGGDDESTFEGCVKGLLWLK
>NC_014824.1|WP_013483545.1|303024_303489_+|hypothetical-protein
MKIKKITMVLSVVISALLCCNFAGYSFIEDENVQYTSESNPERISPLSYNISYSSKGSSDSSSLKKINSNDDPQKEEPVSVIDITEPSLNESCQVVPVDTGDNESSCDSSCEENKEETIVEEKAQKPGYTIITDIIELDTYIYNQLGGSIYSSS
>NC_014824.1|WP_013483544.1|302359_302896_+|hypothetical-protein
MGQYFKAIMKTLNGKNVVFKNPKNYLKLMEHSWYKNTFVNSITELLYHSPAQISWVGDYADKNTESYRIAYNKKAQTIIPDPSTFNLDNKFLVNHSKKTYIDINKYKMLSKDPDGEIVHPLPLLTAEGNGEGGGDYYSESHFNDVGLWAMDLVSVEDEIPNGYSEFEVFFIENYYKIG
>NC_014824.1|WP_013483543.1|301861_302200_+|hypothetical-protein
MKIFTAYDIDWDVDINEIYEAFEKMTIYDAAKELCITADTYADMKTVDRHEIIRDKLYHNRINAAEIVGLPDEVIIPDFFGLKSEKDDTGEVTDWLSDEYGYCINNYKVKYS
>NC_014824.1|WP_013483542.1|301374_301686_+|hypothetical-protein
MNDVKEEKLEYYQCLKLLEYLVEIGLIQKNPQIPSDILVFCEGNGEEYPEGWYSENIFDAARDLVNKPDEQRILLDAIEEKGFKKPELPKFETVRLDVEKFFS
>NC_014824.1|WP_013483541.1|300650_301361_+|hypothetical-protein
MGLDMYLYKVSTPEINEGEIINDIHEDPRCSGVKFINTDAENVLCDTIKKIAVKCIITERYYNMRKIITDYLMNFDVLEEKASEYAEKFYQGGSSYSCTKQSFSLYCDDNEEVKRILNSIGNSGETILETTPSMTTSIRYEKDYDRIVVSFTVNETNMHYEGKYLITKNNKKYAVIMKEVDYQRKGLNDTGWSLLPENCCYCDDKDLICEMTEDGGLSESFMENWIDNETVFWPWW
>NC_014824.1|WP_013483540.1|299431_300517_+|site-specific-DNA-methyltransferase
MTLIQKVIRLLSINHDGLTTKELYEKLPEYSPTGIRGVISRYLRTNETPAFERKEAGVFVLIEVIKAEKNEEGISLSYRASYDTLENGSVDLFYKDVFVENEMIEEGVYEQRRAFADEQDFFNAKINLQAVLAHADAKTILNKLKTESFDMILTDPPYRVISGGTGGKNAPKGMLSKNDGKIFDNNDIQFDEYIPECYRVLKPDRQAYFFTNFLNLQQLIEAVQRSGFKVHNLLVWLKNNATPNRWYMKNCENVLFCYKGKAKAISNCGSKTVHQFDNIKGPKLHETEKPVELLKMYIENSTEEGEWILDPFAGSGSTMAASLLLNRKVFTCEIDKKYLNVIKTRAISILKSGEDDRNLVV
>NC_014824.1|WP_013483539.1|298937_299222_+|hypothetical-protein
MNYKNGKYILDDGHIVPSYEAIQIYNVVEFNSRKEEVYDMYLSVNKDKKIPDDFFESVKLRELTDDYIDAITNENDNLSDILYNVVKSGCKKEI
>NC_014824.1|WP_013483538.1|297762_298551_+|hypothetical-protein
MSHYSLIAIGFENEEDLENMMSIYDESRKVAPHIDMTKEKIYENAQAFYQEKCKLIEAYERNPEKAVAEHGERAKEFYENRHIDGYLGCYENPEDYYKQIISHRKTDRNGNVLTMSNSEAKWDYYDVEKETTIGKIKEEYRKAREKFDSSRLEFIWNVVVNGIKPEKMDLDHFMLLWGVPSKEEMLKLYKSKEEYISFHRDTFCPSYSVLLPEGWFEPGTVGSFGLSTASPAEEHEFRKNYYKEFIEPYDDDTNVFVIDCHI
>NC_014824.1|WP_013483537.1|296505_297228_+|hypothetical-protein
MKLFLSLQAVLIAITVILCFHAKSLTDNVGITEMNSIEKIHQSDCDYIAVIHDTEELDDRFTQFDRENADLGTQTYGTAIFIGTPKDSFSFSNSSTFCTIDVDKVIKGNIKTKSINVEIKGGFYYETESEHMERLSDAKDMEIETPAERLFTFDLGGMNFMNPGKKYLIISQTLDLGDKTFYRINGYMISWLCLDKTESKIMKTEYVYSDCFDNEIFTPEQEIIEAFYSKKESILNKYCK
>NC_014824.1|WP_013483547.1|305151_306264_+|dockerin-type-I-repeat-containing-protein
MNKFGKIVSSLTALMILGSTFTVNAGAETFYTKGDINNSGTVNITDIIKIASHIKSKKMLSEERNDILVPYTTLWAADVNRDGKLNITDITTIAAQIKNVKSISSSTNAFKNVRKLTTPTETDIIARALRLTEANLKYYSPNEPRKYDFTKGNDKAEKIILKEGIDCSGIINYALGTLGIETEGLRGSSNTNAAQFGYTPAATGDWLNKYNVIKPVKNAYWIVDGTKKPMKVLKNGVSTSKQKYYQYGKNNDIIPVGSIVVAFAEDNKGNRMANADHMWLYLGEYNNANEVRKYIASLTDKAPGDIMTRIGSQKIGYNSNNSDNDGKHWRLESTGTWHGFDNFTGPQINNDLCNNTKTQYLIYVFAPPTF
>NC_014824.1|WP_013483548.1|306553_307429_+|IS1595-family-transposase
MSKRFPKPEITLDGIYSKFADESFCKDFLLDIRFEKGFACPFCGGSEYRRIRSRHLLRCKFCKADISATNGTFMHRTHIPLRLWIVTAFLIMSNKCSVSAVTLMRSLGVTYKTAWYILHRIRKAMKCREERYLLDGIVELDDTYLGAPTHGKKRGRGTEKVKMIVALSKNAAGNPEYVKMSDVPNLKGITVGRFARDNIRAGSKIESDNARSYKKPLAQKYFHVFETYDPTSGQLNWMHKVISNFKAMIMGTYHGNEKIHTALYAAEYCYKFNRRKLGNSAYLRLLAALVQ
>NC_014824.1|WP_013483549.1|307550_308138_+|hypothetical-protein
MNEVKNEISEWKGYSFEFRNDAYEVKVRNLEIEQDEYTVFLYADDIKVERNGSEMTEKDFGTTWSGRKMTEKDLLQQSLALYVNGVKDFSMHESLDELDIVYNKLHEKGRIKDINEAYLTPDGHILHLQFVTENSIGYVGVDDLCVAIRADTKESITDIEFFYEQLVYDLVKENTAFIYQTEELKEWIKTFETEE
>NC_014824.1|WP_013483550.1|308140_308509_+|hypothetical-protein
MEITEDKIVYGKNTFTIVNEVPDGYKIWNIGPYMLKGFIPLCRLKQELLQKGLYVIEKDCLLAIKSEGSDKIMAAIGGGYHTVALMEKFLSDNPEPKKDSWEAKQVSRINAALPYMKKIKGL
>NC_014824.1|WP_013483551.1|308528_308801_+|hypothetical-protein
MSKIYRVPVYYQVSEYVPVKAFSKEEAIKYVRDHQDKIPTHCGDANYIDESYEIESDPDVVLGCDEKSGLWEREAWNNEYYDATKENKDG
>NC_014824.1|WP_013483552.1|308793_309042_+|hypothetical-protein
MDNLNGDYIRGYTTALINVLNFFDDHSEAMKVNKMYNQNCVRAVLNFLLENKEEMRETGTIEDIVVSKEKNKVIIKKIGRYF
>NC_014824.1|WP_050793327.1|309054_309285_+|hypothetical-protein
MYNKYESRWNLIQEILELQKQYHKLYTSSKITKSAICELVVPFRDKYELSDVEALNIAKEFCSMERIVRLAEKLFP
>NC_014824.1|WP_013483553.1|309602_311552_+|leucine-rich-repeat-protein
MNINIKSKRIIAGVMALSIVSSGAIASESSVIGRLILLNSLSASAGTVYGDWEYEVTGDHTAKLVKYTGSDAEISIPQGIDGHSITELGENLFSNNTNIKSVKIPRGIQSIPGYCFSNASNLESVVMPLGVTKIERGAFMNAKSLTSIALPLSVDTIESSAFTGSGITSINMRDVNEFGKRIFTDCKNLKDVVLPDGITIIPESTFENCIGIESIILPDDLITIEKNAFKGCTNLTEINAPDSLTTIKNSAFMNCSKLKKTPCSESTVSIEFAAFRNCTGLESVSFSNSPTSIGSYAFAGCEKLEYISIPDSVEKIDSDAFSECKGIRSIDLDVNSATKFGGYCFKGCSSVENINVSDFDILAGLFDKRTFSGCKELRTINNESPVILNGDNTEPEFTEKYRSVIIENFDAIDDSELGFFNDYLEAEVKYVVSTNITDDMSDMEKIKTLHDWLCNKVFYKYIKKNSKYTPDTSNYTQVDSSAFIRNSTVCAGYAKALTLLLNESGVEAYLLVNFSEHAWCMVRVGDHYFHLDATHDDSGSDPNGTIGYDHFLISDTDVKKCSSGHSSWAIDAPTSRYKYTIPDEIPKCLYSVGDVNKDGVINDDDADLIWYYCNGDIGSIDLVLADTNFDGKVDWDDYLAALKRKLPRG
>NC_014824.1|WP_013483554.1|311828_312350_+|hypothetical-protein
MGSVIELNECPKCSFEEMSCEYWYRSDEYSELCPKCGYFRKKFLKRDDNREPIMLTEDIRREDVVVLKNNKWVSPEKDEDLSDYPTSNFAVIMSDEIMRYPSFARMDKDGTKVTYPDYITETGGGCGAVHVKYSNNLERIISLGEKGDSERIKKAVYEEDTTKDIVSIEITCP
>NC_014824.1|WP_013483555.1|312389_312881_+|hypothetical-protein
MLYGKSVRYDKRNFIYAVKTVAELYKSLDMMQSIGIMVEGAKEGVGACIWKSITSSTNIALLLMNHSIGDDLANEVFLDFVERYIKNNMIDKDISAFYATYKNFGNNAAMVKHELERLNSRYDYYCDDCPTRRNGEECDIDCQSKKESLLKRIKQLRRVESNL

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Crispr_ID: NC_014824_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014824_3

313733-313900

TypeV-U3

Consensus_repeat	Method
TCGAACACTATGATGCAATCTGCACTACGCAAGTGAATTGCGAG	PILER-CR
TGCAATCTGCACTACGCAAGTGAATTGCGAG	CRISPRCasFinder

2 spacers

c2c10_CAS-V-U3

The CRISPR arrays of NC_014824_3

>merge|NC_014824|3|313733-313900|PILER-CR,CRISPRCasFinder
GATGCAATCTGCACTACGCAAGTGAATTGCGAGTTCGGCGTTGCTGCTTGATGAATCGGGCACTATCGATGCAATCTGCACTACGCAAGTGAATTGCGAGGTATATTAATTTGTACAAAAGCAGTCGAACACTTTGTTGCAATCTGTACTACGCAAGTGAATTGCGAG

>NC_014824|3|2|313733-313900|PILER-CR
GATGCAATCTGCACTACGCAAGTGAATTGCGAGTTCGGCGTTGCTGC	TTGATGAATCGGGCACTATC
GATGCAATCTGCACTACGCAAGTGAATTGCGAGGTATATTAATTTGT	ACAAAAGCAGTCGAACACTTTGTT
GCAATCTGTACTACGCAAGTGAATTGCGAG

>NC_014824|3|3|313735-313900|CRISPRCasFinder
TGCAATCTGCACTACGCAAGTGAATTGCGAG	TTCGGCGTTGCTGCTTGATGAATCGGGCACTATCGA
TGCAATCTGCACTACGCAAGTGAATTGCGAG	GTATATTAATTTGTACAAAAGCAGTCGAACACTTTGT
TGCAATCTGTACTACGCAAGTGAATTGCGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014824.1\|WP_013483549.1\|307550_308138_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483556.1\|312900_313416_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483551.1\|308528_308801_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483562.1\|319117_319246_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483566.1\|320467_320788_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483557.1\|314124_314745_+\|SMI1/KNR4-family-protein	unknown	unknown	gnl\|CDD\|378155
NC_014824.1\|WP_028504370.1\|318577_319054_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|394873
NC_014824.1\|WP_013483552.1\|308793_309042_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483567.1\|320801_320996_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483550.1\|308140_308509_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483564.1\|319700_319964_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_050793327.1\|309054_309285_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_154662861.1\|314782_314926_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483548.1\|306553_307429_+\|IS1595-family-transposase	unknown	unknown	gnl\|CDD\|372298
NC_014824.1\|WP_013483558.1\|315156_315414_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483560.1\|317780_318581_+\|DUF4241-domain-containing-protein	unknown	unknown	gnl\|CDD\|379427
NC_014824.1\|WP_154662860.1\|316066_317434_+\|transposase	c2c10_CAS-V-U3	-	gnl\|CDD\|284650
NC_014824.1\|WP_013483555.1\|312389_312881_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483554.1\|311828_312350_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483553.1\|309602_311552_+\|leucine-rich-repeat-protein	unknown	unknown	gnl\|CDD\|275383

Protein	Function_ID	Function_description	E-value
NC_014824.1\|WP_013483548.1\|306553_307429_+\|IS1595-family-transposase	gnl\|CDD\|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	7.81236e-18
NC_014824.1\|WP_028504370.1\|318577_319054_+\|hypothetical-protein	gnl\|CDD\|394873	cd02901, Macro_Poa1p-like, macrodomain, Poa1p-like family. Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. Members of this family show similarity to the yeast protein Poa1p, reported to be a phosphatase specific for Appr-1"-p, a tRNA splicing metabolite. Poa1p may play a role in tRNA splicing regulation.	4.43524e-31
NC_014824.1\|WP_154662860.1\|316066_317434_+\|transposase	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	8.78408e-19
NC_014824.1\|WP_013483557.1\|314124_314745_+\|SMI1/KNR4-family-protein	gnl\|CDD\|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	2.93412e-09
NC_014824.1\|WP_013483560.1\|317780_318581_+\|DUF4241-domain-containing-protein	gnl\|CDD\|379427	pfam14025, DUF4241, Protein of unknown function (DUF4241). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 205 and 315 amino acids in length. There is a conserved GDG sequence motif at the C-terminus.	7.30446e-20
NC_014824.1\|WP_013483553.1\|309602_311552_+\|leucine-rich-repeat-protein	gnl\|CDD\|275383	sd00036, LRR_3, leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	8.32352e-36

>NC_014824.1|WP_013483556.1|312900_313416_+|hypothetical-protein
MSYHVWSVDGYGFDVSNTINNLTLEKWSLLKENIRLFWEEKKPYSDEDYPEAKNFFNIPVDVNDIKQDIQNARELFSEYESPFYCLYGFDDLVAEIFVWLWQKNGHIEDLVEIVIDEFTDSHTYWLLGMVYPWRKVEKFDSKEDCRNAIIKSMKGFVEAGNVNFESIEQGG
>NC_014824.1|WP_013483555.1|312389_312881_+|hypothetical-protein
MLYGKSVRYDKRNFIYAVKTVAELYKSLDMMQSIGIMVEGAKEGVGACIWKSITSSTNIALLLMNHSIGDDLANEVFLDFVERYIKNNMIDKDISAFYATYKNFGNNAAMVKHELERLNSRYDYYCDDCPTRRNGEECDIDCQSKKESLLKRIKQLRRVESNL
>NC_014824.1|WP_013483554.1|311828_312350_+|hypothetical-protein
MGSVIELNECPKCSFEEMSCEYWYRSDEYSELCPKCGYFRKKFLKRDDNREPIMLTEDIRREDVVVLKNNKWVSPEKDEDLSDYPTSNFAVIMSDEIMRYPSFARMDKDGTKVTYPDYITETGGGCGAVHVKYSNNLERIISLGEKGDSERIKKAVYEEDTTKDIVSIEITCP
>NC_014824.1|WP_013483553.1|309602_311552_+|leucine-rich-repeat-protein
MNINIKSKRIIAGVMALSIVSSGAIASESSVIGRLILLNSLSASAGTVYGDWEYEVTGDHTAKLVKYTGSDAEISIPQGIDGHSITELGENLFSNNTNIKSVKIPRGIQSIPGYCFSNASNLESVVMPLGVTKIERGAFMNAKSLTSIALPLSVDTIESSAFTGSGITSINMRDVNEFGKRIFTDCKNLKDVVLPDGITIIPESTFENCIGIESIILPDDLITIEKNAFKGCTNLTEINAPDSLTTIKNSAFMNCSKLKKTPCSESTVSIEFAAFRNCTGLESVSFSNSPTSIGSYAFAGCEKLEYISIPDSVEKIDSDAFSECKGIRSIDLDVNSATKFGGYCFKGCSSVENINVSDFDILAGLFDKRTFSGCKELRTINNESPVILNGDNTEPEFTEKYRSVIIENFDAIDDSELGFFNDYLEAEVKYVVSTNITDDMSDMEKIKTLHDWLCNKVFYKYIKKNSKYTPDTSNYTQVDSSAFIRNSTVCAGYAKALTLLLNESGVEAYLLVNFSEHAWCMVRVGDHYFHLDATHDDSGSDPNGTIGYDHFLISDTDVKKCSSGHSSWAIDAPTSRYKYTIPDEIPKCLYSVGDVNKDGVINDDDADLIWYYCNGDIGSIDLVLADTNFDGKVDWDDYLAALKRKLPRG
>NC_014824.1|WP_050793327.1|309054_309285_+|hypothetical-protein
MYNKYESRWNLIQEILELQKQYHKLYTSSKITKSAICELVVPFRDKYELSDVEALNIAKEFCSMERIVRLAEKLFP
>NC_014824.1|WP_013483552.1|308793_309042_+|hypothetical-protein
MDNLNGDYIRGYTTALINVLNFFDDHSEAMKVNKMYNQNCVRAVLNFLLENKEEMRETGTIEDIVVSKEKNKVIIKKIGRYF
>NC_014824.1|WP_013483551.1|308528_308801_+|hypothetical-protein
MSKIYRVPVYYQVSEYVPVKAFSKEEAIKYVRDHQDKIPTHCGDANYIDESYEIESDPDVVLGCDEKSGLWEREAWNNEYYDATKENKDG
>NC_014824.1|WP_013483550.1|308140_308509_+|hypothetical-protein
MEITEDKIVYGKNTFTIVNEVPDGYKIWNIGPYMLKGFIPLCRLKQELLQKGLYVIEKDCLLAIKSEGSDKIMAAIGGGYHTVALMEKFLSDNPEPKKDSWEAKQVSRINAALPYMKKIKGL
>NC_014824.1|WP_013483549.1|307550_308138_+|hypothetical-protein
MNEVKNEISEWKGYSFEFRNDAYEVKVRNLEIEQDEYTVFLYADDIKVERNGSEMTEKDFGTTWSGRKMTEKDLLQQSLALYVNGVKDFSMHESLDELDIVYNKLHEKGRIKDINEAYLTPDGHILHLQFVTENSIGYVGVDDLCVAIRADTKESITDIEFFYEQLVYDLVKENTAFIYQTEELKEWIKTFETEE
>NC_014824.1|WP_013483548.1|306553_307429_+|IS1595-family-transposase
MSKRFPKPEITLDGIYSKFADESFCKDFLLDIRFEKGFACPFCGGSEYRRIRSRHLLRCKFCKADISATNGTFMHRTHIPLRLWIVTAFLIMSNKCSVSAVTLMRSLGVTYKTAWYILHRIRKAMKCREERYLLDGIVELDDTYLGAPTHGKKRGRGTEKVKMIVALSKNAAGNPEYVKMSDVPNLKGITVGRFARDNIRAGSKIESDNARSYKKPLAQKYFHVFETYDPTSGQLNWMHKVISNFKAMIMGTYHGNEKIHTALYAAEYCYKFNRRKLGNSAYLRLLAALVQ
>NC_014824.1|WP_013483557.1|314124_314745_+|SMI1/KNR4-family-protein
MAVKKKLPALKRLIKKIEKVTHVRPATEEELAALQKLAGGKLPEEAMEFYSHYSFEGIVRIDEYIDLYGINEIVRWNTDAVPGFMVLPFGLLTVASWVDGDAICIDLNSVGEKFGYGGCYTTQVIRQCSHELFSEGEEITFYRKALGGLVRLPYTRENVVALSPYVTNDFSYLLKRLRDGELRYIELTKTLDDYEKKRLQETAQES
>NC_014824.1|WP_154662861.1|314782_314926_+|hypothetical-protein
MGKRTNSFIAKIYGCLDESLDAHTTMAYINRKALGNAVKAFLRAFWR
>NC_014824.1|WP_013483558.1|315156_315414_+|hypothetical-protein
MKGIMPDHKEWRKKRYKIFNEKINYFKDHPKYEWLRKYADDAMNANEGFGYLMIKGADFIERIEKMPLEYIRDWLNGKNKLEWTT
>NC_014824.1|WP_154662860.1|316066_317434_+|transposase
MKMTKVVKLALISNVTDKDGNKVEYNELNRCLWDLQKETRDLKNAVVRECWEWYGFTNDYYKLNEEYPNERDYLKKAKSDGTIKDYALDGFIYAKYSKKYNLHSGNYSQTLRDACGSFKNNLKEILRGDKSILSYRADQPLDIKKTCIGLEYDKDTNTYYVTLVLLNKNGVKHYNISDFRFKITVKDNSTRTILERCFDGVYGISASKLIWNRKKSQWFLNLCYSFDKVEVKELDKKKILGVNLGVYYPLYASISGEKDRLAISGDEIIEFRKRIEARRTALKKQAAVCGDGRIGHGYKTRMKPLQNVSDKIANFRDTFNHKASKKLIDFAIKNDCGIIQLENLKGVTKNSEGFLKNWSFYDLQSKIENKAKERGIKVVYIEPAYTSLRCSKCGCIHKDNHPTREQFICQECGYRVLHDYNASQNIAVKDIDKIIKAELEKTEPEKKTEEEKPEK
>NC_014824.1|WP_013483560.1|317780_318581_+|DUF4241-domain-containing-protein
MKEFKNANNGTSEKNNINGTIISDIIVTIFSSKKENSSLNQEMIKRRAEIIEDIGIHSKPSGGDNFWLFYENYIFSKKEHDKIKAIVDKYSSEHYFNELVHIDMNCLYDYTESGTITLSTRVRISDLCYDMDTWCAGSLENVLPGTYNCFVQKTGEGRVAGIKIVHEEYDPEEYEPDELQDIDVGVDSGECGIYDEEYFAKNCKDQDWYESTYVLRDGMPLDDKAFISSSGYGDGSYECFVARNTEGKIVAIKILFIDFENDEEEE
>NC_014824.1|WP_028504370.1|318577_319054_+|hypothetical-protein
MMIYKEEVRDLFTTSDDYILVHCISSDFALGAGIAKKFAQMGVKEKLVKNYPKNWEGHGYMIPVGLKDKMVANLITKEKYWMKPTYDTLRESLENLKNWVIDENYLPWGDIRPIGIQRKLAMPLIGCGLDKLKWDNVRQIIKEVFENTDIEILVCLYK
>NC_014824.1|WP_013483562.1|319117_319246_+|hypothetical-protein
MKEFNVTIIETLKRTVTVEAEDLSGVEFETQEDNTEAEIETG
>NC_014824.1|WP_013483564.1|319700_319964_+|hypothetical-protein
MQISYQKKANGETDKKNLTELEKLKRKDNDLYFSNGKPKKMHMMCRDPSYIREIIHINGRYILDWCCAGGRCPFYSTGCDDKGREWE
>NC_014824.1|WP_013483566.1|320467_320788_+|hypothetical-protein
MAEAERNILVIIRGIPSVHLKGHVSRHFIIGGMRYEYTTGTQECSEEEFIAACESKGWKCMIENNIIYIQGKHHKVFIEPEGMVFIDGYPYSIEDQIYEQNKKFRY
>NC_014824.1|WP_013483567.1|320801_320996_+|hypothetical-protein
MLDKKTEDKIETHLLSAAKLLRKLQFDDWASDLEAASHAIQKDFEEEDNEYTRKFGFSHREVEL

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Crispr_ID: NC_014824_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014824_4

390959-391072

TypeV

Consensus_repeat	Method
GCCTGTTGCAGTGATCGTACCGCCGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014824_4

>merge|NC_014824|4|390959-391072|CRISPRCasFinder
GCCTGTTGCAGTGATCGTACCGCCGTTGATTGTGATATCGCCACAAGATGTATCTGGACCGCCTCCAATACCGGCAGCACTATCGCCGCCTGTTGCAGTGATCGTACCGCCGTT

>NC_014824|4|4|390959-391072|CRISPRCasFinder
GCCTGTTGCAGTGATCGTACCGCCGTT	GATTGTGATATCGCCACAAGATGTATCTGGACCGCCTCCAATACCGGCAGCACTATCGCC
GCCTGTTGCAGTGATCGTACCGCCGTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_014824.1\|WP_013483640.1\|395992_396946_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NC_014824.1\|WP_013483623.1\|384945_385761_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|225806
NC_014824.1\|WP_013483638.1\|394596_395115_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483634.1\|392488_393040_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483628.1\|387759_388500_-\|ubiquitin-family-protein	unknown	unknown	gnl\|CDD\|340501
NC_014824.1\|WP_013483622.1\|383618_384953_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NC_014824.1\|WP_013483633.1\|391972_392470_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483631.1\|389361_390570_-\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	unknown	unknown	gnl\|CDD\|176528
NC_014824.1\|WP_013483641.1\|396990_398160_-\|DNA-primase	unknown	unknown	gnl\|CDD\|235551
NC_014824.1\|WP_013483624.1\|385757_385997_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483642.1\|398654_398921_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483637.1\|394263_394593_+\|DNA-primase	unknown	unknown	gnl\|CDD\|379495
NC_014824.1\|WP_157865507.1\|389079_389262_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483635.1\|393533_393899_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483627.1\|387240_387747_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483636.1\|393917_394220_+\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483629.1\|388499_389051_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_037305308.1\|395342_395867_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367892
NC_014824.1\|WP_013483626.1\|386661_387228_-\|hypothetical-protein	unknown	unknown	unknown
NC_014824.1\|WP_013483625.1\|386149_386569_-\|dockerin-type-I-repeat-containing-protein	unknown	unknown	gnl\|CDD\|271215

Protein	Function_ID	Function_description	E-value
NC_014824.1\|WP_013483640.1\|395992_396946_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	2.11863e-15
NC_014824.1\|WP_013483623.1\|384945_385761_+\|AAA-family-ATPase	gnl\|CDD\|225806	COG3267, ExeA, Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion].	8.11979e-35
NC_014824.1\|WP_013483628.1\|387759_388500_-\|ubiquitin-family-protein	gnl\|CDD\|340501	cd01803, Ubl_ubiquitin, ubiquitin-like (Ubl) domain found in ubiquitin. Ubiquitin is a protein modifier in eukaryotes that is involved in various cellular processes, including transcriptional regulation, cell cycle control, and DNA repair. Ubiquitination is comprised of a cascade of E1, E2 and E3 enzymes that results in a covalent bond between the C-terminus of ubiquitin and the epsilon-amino group of a substrate lysine. Ubiquitin-like (Ubl) proteins have similar ubiquitin beta-grasp fold and attach to other proteins in a Ubl manner but with biochemically distinct roles. Ubiquitin (Ub)and Ubl proteins conjugate and deconjugate via ligases and peptidases to covalently modify target polypeptides. Ub includes Ubq/RPL40e and Ubq/RPS27a fusions as well as homopolymeric multiubiquitin protein chains.	1.49808e-46
NC_014824.1\|WP_013483622.1\|383618_384953_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	8.29887e-22
NC_014824.1\|WP_037305308.1\|395342_395867_+\|hypothetical-protein	gnl\|CDD\|367892	pfam04275, P-mevalo_kinase, Phosphomevalonate kinase. Phosphomevalonate kinase (EC:2.7.4.2) catalyzes the phosphorylation of 5-phosphomevalonate into 5-diphosphomevalonate, an essential step in isoprenoid biosynthesis via the mevalonate pathway. This family represents the animal type of the enzyme. The other is the ERG8 type, found in plants and fungi, and some bacteria (see pfam00288).	0.0019249
NC_014824.1\|WP_013483631.1\|389361_390570_-\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	gnl\|CDD\|176528	cd08586, PI-PLCc_BcPLC_like, Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins. This subfamily corresponds to the catalytic domain present in Bacillus cereus phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) and its sequence homologs found in bacteria and eukaryota. Bacterial PI-PLCs participate in Ca2+-independent PI metabolism, hydrolyzing the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. Bacterial PI-PLCs contain a single TIM-barrel type catalytic domain. Their catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This family also includes some uncharacterized eukaryotic homologs, which contains a single TIM-barrel type catalytic domain, X domain. They are similar to bacterial PI-PLCs, and distinct from typical eukaryotic PI-PLCs, which have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains, and strictly require Ca2+ for their catalytic activities. The prototype of this family is Bacillus cereus PI-PLC, which has a moderate thermal stability and is active as a monomer.	2.86903e-60
NC_014824.1\|WP_013483641.1\|396990_398160_-\|DNA-primase	gnl\|CDD\|235551	PRK05667, dnaG, DNA primase; Validated.	1.39534e-94
NC_014824.1\|WP_013483625.1\|386149_386569_-\|dockerin-type-I-repeat-containing-protein	gnl\|CDD\|271215	cd14256, Dockerin_I, Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.	4.84845e-15
NC_014824.1\|WP_013483637.1\|394263_394593_+\|DNA-primase	gnl\|CDD\|379495	pfam14191, YodL, YodL-like. The YodL-like protein family includes the B. subtilis YodL protein, which is functionally uncharacterized. This domain family is found in bacteria, and is approximately 100 amino acids in length. There are two completely conserved residues (Y and D) that may be functionally important.	8.70867e-33

>NC_014824.1|WP_013483631.1|389361_390570_-|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein
MGQGGAVNLINNTRSKLIQAEPFFTYQMDAWDFPKELEAGEKARFYVEWSEGFFEDRCDDRGIAKYVLENDPKKKVKIEMWDATKRNFTVERTGFSGDDSRSTESILWQHDGDMFIVISDDASKLDFRCWMKGIAGNTPLNKMDIPGTHDSLSYDFTGAGSRIDYTAKTQSYNIWEQLNNGCRYFDIRIDADLRGCHWIIDCVHGLEDFMTWVNRFLNDNPSETIIVRLKNERDVGVDDKKHYNELLSALFEKYKHLFWKSNGQINWPLLDDVRGKIVVLDNLNEHFFSANGYGFVYGDNAKFVIQDNYNAPNEDDKIREIKANIDLPYDSERMKINHISATGTTAGFIPFTWTPRMYADFLNPKVTEFIITKRADCVMGIIVFDFVNSQLVSSVLLNDVIG
>NC_014824.1|WP_157865507.1|389079_389262_-|hypothetical-protein
MSAFADTTINEKSVPQSGQTNVTLDIAPAYIVTIPADTTVTLNDTLTDNGANVETVLIAK
>NC_014824.1|WP_013483629.1|388499_389051_-|hypothetical-protein
MKKLISGMTAFTIASMMTVTAFAEAAISNTTITPKGGDPFDVNPTPETAGSTVEFNVDPTYTVTIPASFELTGEYGQQYSGSGTIQTGKVFLNEGEKIVVTLTSASKFNMSHEGAGEYKLPYTAEGNFGKLTNKETGGKVAEFPTSTEPASAGISFTTDETPTFAGKYTDPVVFGISIEKEPS
>NC_014824.1|WP_013483628.1|387759_388500_-|ubiquitin-family-protein
MKTKRLLAAGMALTMITSVCTLTANAMQIFVKTLTGKTITLDVEPSDTIENVKAKIQDKESIAPNKQRLIFAGKQLEDDRTLADYNIQKESTLHLVLRANGDIEIVPDPDNMPNPIPSTAGMEVSYDVSPTYSVVIPASVSLSDTAETTRQITATNVRLTQNAKIVVTIDSASNTESGDTFNAKIGDSTANYTIKSGDTNVSVGGTVAEFDTKTGEQSKTLAFSKATGATYAGKHTETLTFGIKVE
>NC_014824.1|WP_013483627.1|387240_387747_-|hypothetical-protein
MKKLISGLSALAILAMPVTAFAEPTTINETSDPQSANAVITTEIAPAYIVTIPLDTKVTFNTENTDFGTIELTKAQLDPGKAVKVSLVTDSKMENKADEEKTLAYTIFEGTSDAVNENVFTSAEYTAVGDKTDLTINITAEDWQTAYAGEYSDTVTFNVEYTDAAPES
>NC_014824.1|WP_013483626.1|386661_387228_-|hypothetical-protein
MKKYAVFLLCLSMLTCTAIPAFAEGEQNPTTGEATIGTEVPETHDLKLTITGDVDVKVNGVDGKEFTVERLSEPVLEIKANDGEKITKVVLNGEDVTDQLKDGKLKLPGIYEDSEYVLSAETENISDPSSKSESSSKKAETVSANSPKPNASNANPATGVAGGVSLGTAVLLAAIGIARNKGSKDEEE
>NC_014824.1|WP_013483625.1|386149_386569_-|dockerin-type-I-repeat-containing-protein
MKIIAQKTLTIYVNSSYAIYGQTLADVTLPTADDGTWAWEDDTLSVGDVGNNTFAATYTPEDTDNYNTLSQDLTVTLLGDINFDGKINVTDIVKIAAHIKGKKILDKTAARAADVNGDSSIDVTDIIMIAAHIKGKKLL
>NC_014824.1|WP_013483624.1|385757_385997_+|hypothetical-protein
MTEELLHDAVLIWLLRRLDLSKARREVFEYFQMLTEQDDGKKISRYDLTMEILDILDRHELHYSDGYICSSCPNEPYPF
>NC_014824.1|WP_013483623.1|384945_385761_+|AAA-family-ATPase
MYEMFYEMKHTPFTRSIPTDMLCKTHQNAEILDRLEYTAMHQLFTLLVGEPGTGKTSALRHLKDKLPEDKYMVIYISDSRLKPRSFYYYTLGMFGCKASIHTSISRQELISQTEIMRSIHNRKVVVIIDEAHLLGKEMLEEARFLLNYRMDSENPVSLILSGQTELWDKLKLSAYRAILGRVDIECFLTPMDFSDTKKYIESQLKYSGHTAPIFTEDAMRSIFEFSGGNPRAINRACTQSLIYGSQMKQTCIDSKSVDIVLKNEVTGVRSS
>NC_014824.1|WP_013483622.1|383618_384953_+|DDE-type-integrase/transposase/recombinase
MGMKDKKLAREIAEQRMIMIAPLLGLPLLSEIYYEKRREISENFELSTRTIQRYVDAYNESGIDGLEPKGRVPEQNPVISKEILEEAIRLRREMPSRSVPTIIKILELEGKVEPDMLKRSTLQKALAKMGYSSAMMKVYQDNGYASQRFARVHRCDLWQGDLKFGPSLNIGGKVQPTYMSCLIDDATRYIIHAQFYGDMEQTIVEDTLKKGIKKYGTPRRIYFDNGSQYRTHWMKRACGLLGIRLLYAKPRNPQGKGKQERFNLTVDSFIDEVGLNPPESIEELNKLFNAWLSECYQNKVHSALGVTPETAFKSDSMPLNYPDEAILASAFLHCETRKVNKSGCISFMGKDYDVGILYAGQTVDVVYDPQNIAKVRIEPKSHEPFYAEPAKIGTHVAKKPTRAEIERIPTDSSRLLDAVIKTADERERRAVISYSIAMGGDEDV
>NC_014824.1|WP_013483633.1|391972_392470_-|hypothetical-protein
MKHTKRLLAAVMALTMVSAIAPMSAFATDITQDTPAPKEGTMNVTYSVNPTYTVTIPASVELGGTATLSTSNVNLATGKKILVKLTAAANTVTGTNFTVKTADAATATYQVKKGDTALALNDTAFEFAYDGTTKTGSGSLSFTEPTDAKFAGTYTDQLTFTISVE
>NC_014824.1|WP_013483634.1|392488_393040_-|hypothetical-protein
MNQKQGITLTKKQLVIVAAIIVLLIAGGIVLGINLSRKNSDRIGDTKPTQQDTTSKANIIELDENAGEYTGEKPKDQGGEEVGIKIPGYPSITIAKDTEDVQMALMNPEGNPCYFKFELVLKDSGETIFESKYVKPGDCIYDVHLNKPLAEGEYPATIKISTIALDQETPLNGANVETVLIAK
>NC_014824.1|WP_013483635.1|393533_393899_+|hypothetical-protein
MKYHIYVSDNYDAEDVVDFYVESEDSPECIVKAVALKTIEDNDLSDDNIESISFNTMENHYGVLIQCHDYHIMVWLADGNIPTITIEQKFLNIAKNIPSDVRYDSDNDKKQLKKMLDEIYK
>NC_014824.1|WP_013483636.1|393917_394220_+|hypothetical-protein
MITITTHKEGFMLERPGTPKMFLSYSDALTLSQAVDRMYHIEDVKTKLEEINESEITEDDIDKICDEYERRLEDDDSWNFMLRDVISEFKKTSKCNNTVK
>NC_014824.1|WP_013483637.1|394263_394593_+|DNA-primase
MNYKIFQMKYSNKTRGAVFSCYETAKKEKPDLSIKDYDMVYSGKTDLSGSDSYALNELYNVFNIRHPKDFKGRSMSVSDVIDLEGRLYYVDTFGFKRINIDFKLIKKEN
>NC_014824.1|WP_013483638.1|394596_395115_+|hypothetical-protein
MYDTKDIRTCSEDEKLTQLAELKGQLIDFFEEFLDSKGVIIPNPERDEDEDLDPEESANIYGSDYDELSDRLMETIENWGLLKPEITVDTPAGQLVAYAGKDLDNPSVGICYRPQSGGEIDLAMAETQGEDLRKNTNVGKKDVVLYKWEDPFLEDYTSKSVFHEKDIERALE
>NC_014824.1|WP_037305308.1|395342_395867_+|hypothetical-protein
MNKTIIVINGKGGCGKDTLCNFASEKYPTLNVSSIDPMKKMAEIIGWNGSKTLEDRKFLADLKSLVTRYNDGANEYILKKAEEFAGLPEYKVMFVHIREPEMIEHFKETVKHRVCGITVVTLLVSRNEKDYLVFGNRADDEVNKYNYDHVFENNDDLHSTKESFLKFLDSVLTD
>NC_014824.1|WP_013483640.1|395992_396946_+|site-specific-DNA-methyltransferase
MDNINVVKTLHLWERINASFKGKVFFIKDVYDRFTEEKKDTIRGRIYEHLGKEFQRIGRGIYFAGSKDEAVALIEGDGRDLSVFSNDSFDCIITDHPWSDEKANKGGNRSFADYETFRYTPDDFKEKARVLKDGCFLVEMIPAENESNYEYLYQIKKMAEAAGFQYYAKVPWTKGTFVGNTGRKAKNQEDMMIFSLGKARSMRPDAKKDKADPTVKHYMSGANGMLPTNFNVQPPDKKSRIHQAEKPMGLVEQILDYLTFEGEIVLDQFAGSGVVGEACINKKRGCVLIEKSKECIKKIIQRLGLSDCSVISSSAIA
>NC_014824.1|WP_013483641.1|396990_398160_-|DNA-primase
MKNNSILKIISVKTSLKHIGNGLYRGKCPFCGAIQLYVFEKENCYHCFNCGKNGDQARFMNENKIHYKDAVGKKNHVIHTKPRDLKTFYELNYEAAKFFFERLFSKKENVCLDYLINKRGLTTETICNFRMGYADGNFTSLKEHMLGLGYTIEQLLQSSLVTVSKNDEIIDFFNNRAIFPFIDINGNIIGFGGRKLDGDNNFKYLNTKNTPCYTKNNFLFSLNYAVKNISKGETPILCEGNLDVISMHQAGFRTAVASCGTALTTKQALLLKRYSDEIIICYDNDDAGIAATEKAIDILESVGFTVYVISIRDAKDPDEFIKKFGAKQFYQLIRNDLKNSIFYRIEQLSQKYDLTDLDAQSYFIKDVTELSLRKNYDPEKAIKETFNFI
>NC_014824.1|WP_013483642.1|398654_398921_+|hypothetical-protein
MNVTFLTKTIDDRFSILELGSNVESMKSLLKAHVKRFLDKKANVTSIEPAMHSSEDMGSVITFSDNKGKEHTARFTLLSGDADEFFKH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_014824_2	2.1\|304559\|37\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304559-304595	37	NC_014833.1	3219188-3219224	0	1.0
NC_014824_2	2.3\|304693\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304693-304725	33	NC_014833.1	3632593-3632625	1	0.97

1. spacer 2.1|304559|37|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to position: 3219188-3219224, mismatch: 0, identity: 1.0

cagccatatcctttatcagccgtccgccgcattcggg	CRISPR spacer
cagccatatcctttatcagccgtccgccgcattcggg	Protospacer
*************************************

2. spacer 2.3|304693|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to position: 3632593-3632625, mismatch: 1, identity: 0.97

aacagacgtacagtttcaagggcgattgagata	CRISPR spacer
aatagacgtacagtttcaagggcgattgagata	Protospacer
**.******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014824_1	1.1\|94040\|33\|NC_014824\|CRISPRCasFinder	94040-94072	33	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	94040-94072	0	1.0
NC_014824_1	1.2\|94118\|33\|NC_014824\|CRISPRCasFinder	94118-94150	33	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	94118-94150	0	1.0
NC_014824_1	1.3\|94196\|33\|NC_014824\|CRISPRCasFinder	94196-94228	33	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	94196-94228	0	1.0
NC_014824_1	1.4\|94274\|33\|NC_014824\|CRISPRCasFinder	94274-94306	33	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	94274-94306	0	1.0
NC_014824_1	1.5\|94352\|33\|NC_014824\|CRISPRCasFinder	94352-94384	33	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	94352-94384	0	1.0
NC_014824_1	1.6\|94430\|30\|NC_014824\|CRISPRCasFinder	94430-94459	30	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	94430-94459	0	1.0
NC_014824_1	1.7\|94505\|30\|NC_014824\|CRISPRCasFinder	94505-94534	30	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	94505-94534	0	1.0
NC_014824_2	2.1\|304559\|37\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304559-304595	37	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	304559-304595	0	1.0
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	304628-304660	0	1.0
NC_014824_2	2.3\|304693\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304693-304725	33	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	304693-304725	0	1.0
NC_014824_2	2.4\|304758\|35\|NC_014824\|CRISPRCasFinder,CRT	304758-304792	35	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	304758-304792	0	1.0
NC_014824_3	3.1\|313780\|20\|NC_014824\|PILER-CR	313780-313799	20	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	313766-313785	0	1.0
NC_014824_3	3.2\|313847\|24\|NC_014824\|PILER-CR	313847-313870	24	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	313833-313856	0	1.0
NC_014824_3	3.3\|313766\|36\|NC_014824\|CRISPRCasFinder	313766-313801	36	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	313766-313801	0	1.0
NC_014824_3	3.4\|313833\|37\|NC_014824\|CRISPRCasFinder	313833-313869	37	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	313833-313869	0	1.0
NC_014824_4	4.1\|390986\|60\|NC_014824\|CRISPRCasFinder	390986-391045	60	NC_014824	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence	390986-391045	0	1.0
NC_014824_1	1.7\|94505\|30\|NC_014824\|CRISPRCasFinder	94505-94534	30	NZ_CP026426	Acinetobacter sp. ACNIH1 plasmid pACI-df08, complete sequence	142663-142692	7	0.767
NC_014824_1	1.7\|94505\|30\|NC_014824\|CRISPRCasFinder	94505-94534	30	NZ_CP026426	Acinetobacter sp. ACNIH1 plasmid pACI-df08, complete sequence	228492-228521	7	0.767
NC_014824_1	1.7\|94505\|30\|NC_014824\|CRISPRCasFinder	94505-94534	30	HQ317387	Sulfitobacter phage phiCB2047-B genomic sequence	68101-68130	9	0.7
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	KX349297	Cyanophage S-RIM44 isolate W2_10_0709, complete genome	15960-15992	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	KX349293	Cyanophage S-RIM44 isolate Np_20_0711, complete genome	15951-15983	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	KX349296	Cyanophage S-RIM44 isolate Sn_13_0910, complete genome	15993-16025	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	NC_047734	Cyanophage S-RIM44 isolate Np_42_0711, complete genome	15948-15980	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	KU594607	Cyanophage S-RIM44 isolate W2_07_0710, complete genome	15960-15992	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	KX349291	Cyanophage S-RIM44 isolate ES_42_0910, complete genome	15993-16025	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	NC_015288	Prochlorococcus phage Syn1, complete genome	15990-16022	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	KX349295	Cyanophage S-RIM44 isolate Sn_08_0709, complete genome	15960-15992	10	0.697
NC_014824_2	2.2\|304628\|33\|NC_014824\|PILER-CR,CRISPRCasFinder,CRT	304628-304660	33	KX349292	Cyanophage S-RIM44 isolate Np_05_0604, complete genome	15960-15992	10	0.697

1. spacer 1.1|94040|33|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

agctatatgttcaacgagtgtggcaaactttat	CRISPR spacer
agctatatgttcaacgagtgtggcaaactttat	Protospacer
*********************************

2. spacer 1.2|94118|33|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

ggtgatatgttctctctttgtgaccaattaaca	CRISPR spacer
ggtgatatgttctctctttgtgaccaattaaca	Protospacer
*********************************

3. spacer 1.3|94196|33|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

agtggtatgttcaattcctgtcttagcttgtca	CRISPR spacer
agtggtatgttcaattcctgtcttagcttgtca	Protospacer
*********************************

4. spacer 1.4|94274|33|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

tgtgatatgttctggggctgtgcaaaattgacg	CRISPR spacer
tgtgatatgttctggggctgtgcaaaattgacg	Protospacer
*********************************

5. spacer 1.5|94352|33|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

ggtggtatgttctgtgcctgtaataaattgact	CRISPR spacer
ggtggtatgttctgtgcctgtaataaattgact	Protospacer
*********************************

6. spacer 1.6|94430|30|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

tcaggaatgttcgcttcaactaacttatca	CRISPR spacer
tcaggaatgttcgcttcaactaacttatca	Protospacer
******************************

7. spacer 1.7|94505|30|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

atggcaatgttctcttcaagaaatttgacc	CRISPR spacer
atggcaatgttctcttcaagaaatttgacc	Protospacer
******************************

8. spacer 2.1|304559|37|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

cagccatatcctttatcagccgtccgccgcattcggg	CRISPR spacer
cagccatatcctttatcagccgtccgccgcattcggg	Protospacer
*************************************

9. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
gtgtaaaagccgtcaacataaaaaccactacta	Protospacer
*********************************

10. spacer 2.3|304693|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

aacagacgtacagtttcaagggcgattgagata	CRISPR spacer
aacagacgtacagtttcaagggcgattgagata	Protospacer
*********************************

11. spacer 2.4|304758|35|NC_014824|CRISPRCasFinder,CRT matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

aagtcatttgcaacagagattttattaaagtggag	CRISPR spacer
aagtcatttgcaacagagattttattaaagtggag	Protospacer
***********************************

12. spacer 3.1|313780|20|NC_014824|PILER-CR matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggcgttgctgcttgatg	CRISPR spacer
ttcggcgttgctgcttgatg	Protospacer
********************

13. spacer 3.2|313847|24|NC_014824|PILER-CR matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

gtatattaatttgtacaaaagcag	CRISPR spacer
gtatattaatttgtacaaaagcag	Protospacer
************************

14. spacer 3.3|313766|36|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggcgttgctgcttgatgaatcgggcactatcga	CRISPR spacer
ttcggcgttgctgcttgatgaatcgggcactatcga	Protospacer
************************************

15. spacer 3.4|313833|37|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

gtatattaatttgtacaaaagcagtcgaacactttgt	CRISPR spacer
gtatattaatttgtacaaaagcagtcgaacactttgt	Protospacer
*************************************

16. spacer 4.1|390986|60|NC_014824|CRISPRCasFinder matches to NC_014824 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL01, complete sequence) position: , mismatch: 0, identity: 1.0

gattgtgatatcgccacaagatgtatctggaccgcctccaataccggcagcactatcgcc	CRISPR spacer
gattgtgatatcgccacaagatgtatctggaccgcctccaataccggcagcactatcgcc	Protospacer
************************************************************

17. spacer 1.7|94505|30|NC_014824|CRISPRCasFinder matches to NZ_CP026426 (Acinetobacter sp. ACNIH1 plasmid pACI-df08, complete sequence) position: , mismatch: 7, identity: 0.767

atggcaatgttctcttcaagaaatttgacc	CRISPR spacer
tactcaatattctcttcaagtaatttgatc	Protospacer
    ****.*********** *******.*

18. spacer 1.7|94505|30|NC_014824|CRISPRCasFinder matches to NZ_CP026426 (Acinetobacter sp. ACNIH1 plasmid pACI-df08, complete sequence) position: , mismatch: 7, identity: 0.767

atggcaatgttctcttcaagaaatttgacc	CRISPR spacer
tactcaatattctcttcaagtaatttgatc	Protospacer
    ****.*********** *******.*

19. spacer 1.7|94505|30|NC_014824|CRISPRCasFinder matches to HQ317387 (Sulfitobacter phage phiCB2047-B genomic sequence) position: , mismatch: 9, identity: 0.7

atggcaatgttctcttcaagaaatttgacc	CRISPR spacer
gaacacatgttctcttccagaaacttgaca	Protospacer
. .   *********** *****.*****

20. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to KX349297 (Cyanophage S-RIM44 isolate W2_10_0709, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

21. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to KX349293 (Cyanophage S-RIM44 isolate Np_20_0711, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

22. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to KX349296 (Cyanophage S-RIM44 isolate Sn_13_0910, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

23. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to NC_047734 (Cyanophage S-RIM44 isolate Np_42_0711, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

24. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to KU594607 (Cyanophage S-RIM44 isolate W2_07_0710, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

25. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to KX349291 (Cyanophage S-RIM44 isolate ES_42_0910, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

26. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to NC_015288 (Prochlorococcus phage Syn1, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

27. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to KX349295 (Cyanophage S-RIM44 isolate Sn_08_0709, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

28. spacer 2.2|304628|33|NC_014824|PILER-CR,CRISPRCasFinder,CRT matches to KX349292 (Cyanophage S-RIM44 isolate Np_05_0604, complete genome) position: , mismatch: 10, identity: 0.697

gtgtaaaagccgtcaacataaaaaccactacta	CRISPR spacer
tcacctgacccatcaacataaaaaccaccacta	Protospacer
 ...  .* **.****************.****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

42211 : 104797

Paenibacillus_phage(50.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080557319.1\|42211_42466_-\|transposase	transposase	NA	NA	NA	NA
WP_013483331.1\|42753_43602_-\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	4.8e-78	65.8
WP_013483332.1\|43643_44327_-	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	7.4e-37	42.8
WP_013483333.1\|44444_45485_-	hypothetical protein	NA	NA	NA	NA
WP_013483334.1\|45606_50730_+	hypothetical protein	NA	NA	NA	NA
WP_013483335.1\|50836_52873_+	hypothetical protein	NA	NA	NA	NA
WP_013483336.1\|52950_53319_+	hypothetical protein	NA	NA	NA	NA
WP_013483337.1\|53377_54268_+	class B sortase	NA	NA	NA	NA
WP_013483338.1\|54282_55749_+	CAP domain-containing protein	NA	NA	NA	NA
WP_013483339.1\|55914_57576_+	DHH family phosphoesterase	A7KV88	Bacillus_phage	3.5e-48	28.3
WP_013483340.1\|57591_58575_+	hypothetical protein	NA	NA	NA	NA
WP_013483341.1\|58722_60516_+	AAA family ATPase	NA	NA	NA	NA
WP_028504252.1\|60584_63293_-	RICIN domain-containing protein	NA	NA	NA	NA
WP_013483343.1\|63405_63717_-	hypothetical protein	NA	NA	NA	NA
WP_013483344.1\|64023_64485_-	hypothetical protein	NA	NA	NA	NA
WP_013483345.1\|64817_65075_+	DUF370 domain-containing protein	NA	NA	NA	NA
WP_013483346.1\|65102_65372_-	hypothetical protein	NA	NA	NA	NA
WP_013483348.1\|65764_66958_+	hypothetical protein	NA	NA	NA	NA
WP_013483349.1\|67024_68767_-	leucine-rich repeat protein	NA	NA	NA	NA
WP_013483350.1\|69090_70752_+	AAA family ATPase	NA	NA	NA	NA
WP_013483351.1\|70816_73207_+	VWA domain-containing protein	NA	NA	NA	NA
WP_013483352.1\|73211_73706_+	hypothetical protein	NA	NA	NA	NA
WP_013483353.1\|73894_75316_+	hypothetical protein	NA	NA	NA	NA
WP_013483354.1\|75395_75611_+	hypothetical protein	NA	NA	NA	NA
WP_013483355.1\|75607_75958_+	hypothetical protein	NA	NA	NA	NA
WP_013483356.1\|75979_76258_+	hypothetical protein	NA	NA	NA	NA
WP_013483357.1\|76930_78451_+	ribonuclease III	NA	NA	NA	NA
WP_013483358.1\|78618_80601_-	type IA DNA topoisomerase	NA	NA	NA	NA
WP_013483359.1\|80606_81383_-	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_013483360.1\|81379_81931_-	hypothetical protein	NA	NA	NA	NA
WP_013483361.1\|81932_82676_-	hypothetical protein	NA	NA	NA	NA
WP_013483362.1\|82840_84166_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_013483363.1\|84915_85359_-	hypothetical protein	NA	NA	NA	NA
WP_013483364.1\|85495_85678_-	hypothetical protein	NA	NA	NA	NA
WP_013483365.1\|86296_86470_+	hypothetical protein	NA	NA	NA	NA
WP_013483366.1\|88009_88441_+	hypothetical protein	NA	NA	NA	NA
WP_013483367.1\|88448_89567_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_080557320.1\|90646_90820_-	DUF434 domain-containing protein	NA	NA	NA	NA
WP_013483369.1\|91098_92625_-	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_050793323.1\|92952_93132_-\|transposase	transposase domain-containing protein	NA	NA	NA	NA
WP_013483370.1\|93619_95065_+	BspA family leucine-rich repeat surface protein	NA	NA	NA	NA
WP_013483371.1\|95183_97859_+	discoidin domain-containing protein	NA	NA	NA	NA
WP_013483372.1\|98337_99507_+	ATP-binding protein	NA	NA	NA	NA
WP_013483374.1\|100181_100406_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013483375.1\|100647_101094_+	hypothetical protein	NA	NA	NA	NA
WP_028504522.1\|101440_101659_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013483378.1\|103678_104797_+\|transposase	transposase	S6AND0	Bacillus_phage	2.5e-82	45.5

DBSCAN-SWA_2

289669 : 332226

Bacillus_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013483531.1\|289669_290995_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_013483532.1\|291274_292552_+	dockerin type I repeat-containing protein	NA	NA	NA	NA
WP_013483533.1\|292913_293204_+	HU family DNA-binding protein	A0A1P8CWT5	Bacillus_phage	8.0e-17	51.7
WP_013483534.1\|294194_295085_+	hypothetical protein	NA	NA	NA	NA
WP_013483535.1\|295096_295852_+	hypothetical protein	NA	NA	NA	NA
WP_013483536.1\|295864_296509_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	4.4e-31	32.1
WP_013483537.1\|296505_297228_+	hypothetical protein	NA	NA	NA	NA
WP_013483538.1\|297762_298551_+	hypothetical protein	NA	NA	NA	NA
WP_013483539.1\|298937_299222_+	hypothetical protein	NA	NA	NA	NA
WP_013483540.1\|299431_300517_+	site-specific DNA-methyltransferase	G8DCV7	Silicibacter_phage	3.4e-52	46.9
WP_013483541.1\|300650_301361_+	hypothetical protein	NA	NA	NA	NA
WP_013483542.1\|301374_301686_+	hypothetical protein	NA	NA	NA	NA
WP_013483543.1\|301861_302200_+	hypothetical protein	NA	NA	NA	NA
WP_013483544.1\|302359_302896_+	hypothetical protein	I3WUU7	Mycobacterium_phage	2.4e-14	25.5
WP_013483545.1\|303024_303489_+	hypothetical protein	NA	NA	NA	NA
WP_013483546.1\|303510_303975_+	hypothetical protein	NA	NA	NA	NA
WP_013483547.1\|305151_306264_+	dockerin type I repeat-containing protein	NA	NA	NA	NA
WP_013483548.1\|306553_307429_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013483549.1\|307550_308138_+	hypothetical protein	NA	NA	NA	NA
WP_013483550.1\|308140_308509_+	hypothetical protein	NA	NA	NA	NA
WP_013483551.1\|308528_308801_+	hypothetical protein	NA	NA	NA	NA
WP_013483552.1\|308793_309042_+	hypothetical protein	NA	NA	NA	NA
WP_050793327.1\|309054_309285_+	hypothetical protein	NA	NA	NA	NA
WP_013483553.1\|309602_311552_+	leucine-rich repeat protein	NA	NA	NA	NA
WP_013483554.1\|311828_312350_+	hypothetical protein	NA	NA	NA	NA
WP_013483555.1\|312389_312881_+	hypothetical protein	NA	NA	NA	NA
WP_013483556.1\|312900_313416_+	hypothetical protein	NA	NA	NA	NA
WP_013483557.1\|314124_314745_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_154662861.1\|314782_314926_+	hypothetical protein	NA	NA	NA	NA
WP_013483558.1\|315156_315414_+	hypothetical protein	NA	NA	NA	NA
WP_154662860.1\|316066_317434_+\|transposase	transposase	A0A142F1Q5	Bacillus_phage	5.4e-71	37.8
WP_013483560.1\|317780_318581_+	DUF4241 domain-containing protein	A0A2K9L024	Tupanvirus	1.4e-10	30.3
WP_028504370.1\|318577_319054_+	hypothetical protein	Q5ULS8	Lactobacillus_virus	7.7e-25	40.9
WP_013483562.1\|319117_319246_+	hypothetical protein	NA	NA	NA	NA
WP_013483564.1\|319700_319964_+	hypothetical protein	NA	NA	NA	NA
WP_013483566.1\|320467_320788_+	hypothetical protein	NA	NA	NA	NA
WP_013483567.1\|320801_320996_+	hypothetical protein	NA	NA	NA	NA
WP_013483568.1\|321208_321727_+	hypothetical protein	NA	NA	NA	NA
WP_013483569.1\|321831_323157_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_013483570.1\|323834_324176_+	hypothetical protein	NA	NA	NA	NA
WP_013483571.1\|324153_324354_+	hypothetical protein	NA	NA	NA	NA
WP_013483572.1\|324518_325592_+	hypothetical protein	NA	NA	NA	NA
WP_013483573.1\|325813_326122_+	hypothetical protein	NA	NA	NA	NA
WP_013483574.1\|326299_326776_+\|transposase	IS200/IS605 family transposase	W0UUZ0	Sulfolobus_monocaudavirus	9.1e-18	34.5
WP_013483575.1\|326997_327717_-	hypothetical protein	NA	NA	NA	NA
WP_037304617.1\|327960_329841_+	dockerin	NA	NA	NA	NA
WP_013483577.1\|330027_330690_+	DUF4314 domain-containing protein	M1PFX9	Streptococcus_phage	3.1e-08	49.2
WP_013483578.1\|331047_331323_+	stage V sporulation protein S	NA	NA	NA	NA
WP_013483579.1\|331581_332226_-\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	5.5e-18	45.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_014825

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_014825_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014825_1

312878-313019

Orphan

Consensus_repeat	Method
TGTTTCTCGGTGCCCTTTGAAGCTTGCAAACAAACACAGCTGCCCTAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014825_1

>merge|NC_014825|1|312878-313019|CRISPRCasFinder
TGTTTCTCGGTGCCCTTTGAAGCTTGCAAACAAACACAGCTGCCCTAGCCAGGGTCGCCGACACGTCACCAACATTGTTATGACGGGCAGTATGTTTCTCGGTGCCCTTTGAAGCTCGCAAACAAACACAGCTGCCCTAGCC

>NC_014825|1|1|312878-313019|CRISPRCasFinder
TGTTTCTCGGTGCCCTTTGAAGCTTGCAAACAAACACAGCTGCCCTAGCC	AGGGTCGCCGACACGTCACCAACATTGTTATGACGGGCAGTA
TGTTTCTCGGTGCCCTTTGAAGCTCGCAAACAAACACAGCTGCCCTAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014825.1\|WP_037303845.1\|308599_309166_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|271355
NC_014825.1\|WP_013483916.1\|319407_320094_-\|SOS-response-associated-peptidase	unknown	unknown	gnl\|CDD\|376837
NC_014825.1\|WP_154662753.1\|315713_317117_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|290319
NC_014825.1\|WP_013483908.1\|311408_312827_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|223545
NC_014825.1\|WP_013483913.1\|317334_317505_+\|hypothetical-protein	unknown	unknown	unknown
NC_014825.1\|WP_013483906.1\|309178_310192_-\|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NC_014825.1\|WP_013483899.1\|298473_299862_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_014825.1\|WP_013483904.1\|306662_308528_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NC_014825.1\|WP_013483917.1\|320554_324178_+\|leucine-rich-repeat-protein	unknown	unknown	gnl\|CDD\|281416
NC_014825.1\|WP_013483901.1\|301521_303327_-\|ammonium-transporter	unknown	unknown	gnl\|CDD\|223083
NC_014825.1\|WP_013483902.1\|303735_305178_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223112
NC_014825.1\|WP_013483918.1\|324318_325686_+\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|237087
NC_014825.1\|WP_013483900.1\|300210_301059_+\|hypothetical-protein	unknown	unknown	unknown
NC_014825.1\|WP_013483910.1\|314770_315511_+\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NC_014825.1\|WP_037304146.1\|317549_318248_+\|endonuclease-V	unknown	unknown	gnl\|CDD\|377374
NC_014825.1\|WP_013483907.1\|310625_311099_-\|hypothetical-protein	unknown	unknown	unknown
NC_014825.1\|WP_013483911.1\|315524_315695_+\|hypothetical-protein	unknown	unknown	unknown
NC_014825.1\|WP_013483909.1\|313424_314771_+\|DUF1727-domain-containing-protein	unknown	unknown	gnl\|CDD\|223840
NC_014825.1\|WP_013483915.1\|318328_319324_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380507
NC_014825.1\|WP_013483903.1\|305440_306592_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|274090

Protein	Function_ID	Function_description	E-value
NC_014825.1\|WP_037303845.1\|308599_309166_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|271355	cd00446, GrpE, nucleotide exchange factor GrpE. GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.	3.55867e-49
NC_014825.1\|WP_013483916.1\|319407_320094_-\|SOS-response-associated-peptidase	gnl\|CDD\|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	1.33386e-39
NC_014825.1\|WP_013483908.1\|311408_312827_+\|pyruvate-kinase	gnl\|CDD\|223545	COG0469, PykF, Pyruvate kinase [Carbohydrate transport and metabolism].	0
NC_014825.1\|WP_013483906.1\|309178_310192_-\|heat-inducible-transcription-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	6.05841e-91
NC_014825.1\|WP_013483899.1\|298473_299862_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.76444e-27
NC_014825.1\|WP_013483904.1\|306662_308528_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NC_014825.1\|WP_013483918.1\|324318_325686_+\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|237087	PRK12391, PRK12391, TrpB-like pyridoxal phosphate-dependent enzyme.	0
NC_014825.1\|WP_013483901.1\|301521_303327_-\|ammonium-transporter	gnl\|CDD\|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	1.88917e-134
NC_014825.1\|WP_013483902.1\|303735_305178_+\|amidophosphoribosyltransferase	gnl\|CDD\|223112	COG0034, PurF, Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism].	0
NC_014825.1\|WP_013483910.1\|314770_315511_+\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.17223e-74
NC_014825.1\|WP_037304146.1\|317549_318248_+\|endonuclease-V	gnl\|CDD\|377374	pfam04493, Endonuclease_5, Endonuclease V. Endonuclease V is specific for single-stranded DNA or for duplex DNA that contains uracil or that is damaged by a variety of agents.	3.73462e-93
NC_014825.1\|WP_013483917.1\|320554_324178_+\|leucine-rich-repeat-protein	gnl\|CDD\|281416	pfam03415, Peptidase_C11, Clostripain family.	6.94648e-33
NC_014825.1\|WP_154662753.1\|315713_317117_-\|IS5-family-transposase	gnl\|CDD\|290319	pfam13586, DDE_Tnp_1_2, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	7.79704e-14
NC_014825.1\|WP_013483909.1\|313424_314771_+\|DUF1727-domain-containing-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	2.72639e-47
NC_014825.1\|WP_013483915.1\|318328_319324_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380507	cd06284, PBP1_LacI-like, ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria. This group includes the ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria. This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.	1.51775e-101
NC_014825.1\|WP_013483903.1\|305440_306592_-\|molecular-chaperone-DnaJ	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	0

>NC_014825.1|WP_013483908.1|311408_312827_+|pyruvate-kinase
MRKTKIVCTIGPATDDENILRDMMKNGMDVARFNFSHSEHSIHQQRFETITRLRDEMGLNIATLMDTKGPEIRLRDFKDHKPVTINDGDMFTLTTRDVEGDNTICSITFPKLPQDITTGTRILINDGVIELKAVKIDSTDIQCEVIHGGVVSDHKGINVPGVKLSMPYISDADMADLAFGAKMGFDFIAASFVRTGADVTYLRKFTQSLGWFNPRIIAKIENAEGVENIDEILEAADGIMVARGDMGVEIPFENIPAIQKELIHKAYNAGKQVITATQMLESMINNPRPTRAEITDVANAIYDGTSAIMLSGETAAGKYPVEVVKTMSLIAETTEGDIDYVRRFQKRDDIDHPSITDAICHATVTTAHDLKAAAILTVTKSGATARILSKYRPDCPIIGLTTDSVTCHQMNMSWGVLPGLVDEMDNTDELISRAIRVALEKGYIKEGDLVVITAGVPLGISGTTNLMKVERA
>NC_014825.1|WP_013483907.1|310625_311099_-|hypothetical-protein
MEKKIKMSMSIMMGVTLSLCLSFVGTFTSGSFTPAAFLVSFLESLVISLVIGCIVPIKKAEDSACEKVGVKSPMGRRTVGSFVSDLIYTPVITTAMVTINFFKIPIAHRPPYIIMWGKSMVISFIVAYLIVFLVGDNYMRMILKKYGITGRPPEGRK
>NC_014825.1|WP_013483906.1|309178_310192_-|heat-inducible-transcription-repressor-HrcA
MDDRKLKILSAVVDEYIVSGEPVGSKAIMAHVKASSATIRNEMAELEKQGYLEQPHTSAGRVPTYKGYRLYVDKLMEQDPLSEEEKTKLDSMLPDDFVTEKDLVESASLALAELTKCATVVANSTPKFSLISKVEVIPTGKRMYVILMITSNGEIKNKVCRLEFDLTHEQLEFFDNFVKQNLSGVPISEISDANMEKLTEAMGAYMMTLSPLVSELLKMTKELDRSVSLKGQKNLLTCKDLDQGEIISFLDNEKELMAFIDGTFSGLNVKFSPETDGFVIHNSSMITAPFSKDGQMAGALGLIGPMRIDYAKFIPYLEYFTSRITDLISEKDDNDDK
>NC_014825.1|WP_037303845.1|308599_309166_-|nucleotide-exchange-factor-GrpE
MDLAFDEEIKEELEEELTEEAEDTADTPEETENEENNESTEQSEEDKLKAELADTKDKYLRLMAEYDNFRKRSAKERLDISASVKADTVADILPVLDNFERALGTETQDEAYKQGIEMIFKQFTDAMAKLGIEAIDPVGEVFDPNIANAVNQIEDPELGENVVAQVFQKGYRIGDKVIRYAMVVVANP
>NC_014825.1|WP_013483904.1|306662_308528_-|molecular-chaperone-DnaK
MAKIIGIDLGTTNSCVAVMEGGEAVVIPNSEGARTTPSVVGLSKTGDRLVGQVAKRQAVTNYENTVISIKRHMGSDYKASMGGKEYTPQEISAMILQKLKADAEAYLGEKVTEAVITVPAYFTDAQRQATKDAGQIAGLTVKRIINEPTAAALSYGIDKEEDQKVMVYDLGGGTFDVSIIEMGDGVTEVLATAGNNKLGGDDFDQRIIDWMVAEFKTAEGVDLTADKLAMQRLKEAAEKAKIELSSTPSSTISLPFITADSTGPKHLEMTLTQAKFNEMTADLVESTMGPVRQALSDSGLSAGDLQKVLMVGGSSRIPAVQEAVKRFIGKEPFKGINPDECVALGAAYQGGVLGGDVKDGLLLLDVTPLSLGLETMGGVCTKIIERNTTIPTKKSQIFSTAADNQSAVDINVLQGEREFARDNKQLGMFRLDGIAPAPRGIPQIEVTFDIDANGIVHVSAKDLGTGKEQNITITSSTNMSKEDIDKAVKEAEAFAAEDAKKKEEVDIRNNGDQLAFQAEKALNDFGDKVDAADKSDCEAKIAALKEALKGTDSADIKAKTEELQKTFEGIATKVYQQAGAQGGAQGFDPNNMNMGGAAAGAADNSDKGGDDVIDAEFTDAD
>NC_014825.1|WP_013483903.1|305440_306592_-|molecular-chaperone-DnaJ
MADKRDYYEVLGVQKGASEDELKKAFRKLAKQYHPDLHPGDKEAEEKFKEINEAYEVLSDPDKRSRYDQFGHAGVDPNYGGGAGAGGFGGFSDMGDIFDSIFGGFGFGGGGRSANPNAPRRGADIRANLTIDFMEACTGKKVKMKYARNETCPDCNGTGAAAGSSPKTCPDCHGTGSVRISQRTPFGNISQTTTCSRCGGKGRVVDNPCKTCGGQGMVKKSVERDIDIPAGIDDGQTLRVAGEGHRGTNGGPSGDLHINITVRPDPIFERDGFDVWTDIPITYAQATLGDEITVPTVCGKVKYTVPEGTQNNTVFRLKGKGIKKLNRNDHGDHYVRINVEVPRNLTREQKEKLREFERSLNEKNYAKKNIFKEKLDKLKDIFK
>NC_014825.1|WP_013483902.1|303735_305178_+|amidophosphoribosyltransferase
MGGLHEECGIIGIFGKEHQPLAETVYYGLYALQHRGQEGCGIAVCDDGVITAHKDTGLVGEVFDHRSLAELPCGTMAIGHVRYSTTGGNERRNCQPIVVNHQKGRMAIAHNGNLSNAAELRSALELTGAIFHTTSDTETIAYEITKMRLKKPSIEDAVLGTMDIIDGAYSLVVMSPTKLIAVRDPYGYRPLCYGTMPDGGYAVASESCALTAIGAEFVRDIEPGEMLIFSNDGMRSDRSHCGIKPKQTCILEYIYFARPDSEIDGVSVHNARLRAGRILAEESPADADIVIGVPDSGLDAALGFSQASGIPYGIGLIKNKYIGRTFIAPTQSTRTDKVRIKLAAVSDTVKGKRVVLVDDSIVRGTTGGRIVVLLREAGAKEIHFRVSAPPFLHPCYYGTDIDSEKGLIADHHTPEEIAAMMGADSLGYLPVERVDELNCGAGCCKACFNGEYGTAIPKGAHKDRYEMKISLTRDANSQLT
>NC_014825.1|WP_013483901.1|301521_303327_-|ammonium-transporter
MDVQEIVQEVTQASDKTVFGVWFMIAVALVFFMQAGFAMVETGFTRAKNAGNIIMKNLMDFCIGTVAFIAIGFGLLLGEDAAGLIGKPGFDIFTSYENFAWDQFVFNLVFCATTATIVSGAMAERTKFLSYCVYSGIISAFIYPVEAHWIWGGGWLAQMGFHDLSGSCAIHMVGGVCALIGAKFVGPRIGKFVKTKDGDIKVNAIPGHNLTIGALGVFILWFGWYGFNPAAASTVGQLDSIFLTTTVAPAIATVTCMVFTWLKYGKPDVSMCLNGSLAGLVGITAGCDVMDCLGAVLVGIVSGFLVCFGVWFLDYKLHIDDPVGAVAVHMMNGIWGTIAVGLFATKTSPGYAIQLECGGIKAEGLFYGGGFEQLGLQLIGFAAVAAWAAVAISITFLIIKKTLGLRASEQEEIIGMDITEHGLVSSYADFAPSMNDASVYGYTKDDAKSVKKVEGQVPALKVPVEKAVEVESYVAPTSDGHPRMTKVVIVFKEQKLQALIQAMEAIDVTGITVTHVIGCGMQNGQRHYYRGTSIEMNLLPKVKAEIVVCAVPVSKVIDAARSALYTGNYGDGKLFIYPIENVIKVRTGEQGYDALQNFDED
>NC_014825.1|WP_013483900.1|300210_301059_+|hypothetical-protein
MNQINNTSKSFMMYKEWEETFLALESDAERGELLRALFVFARTGDIPEFKGGLKIAFLQMSNQLRRDAEKYEKKCERNRANANKRWGNNNNAVASESIPKDAVYADKDKEEEKDKEKDKDKYKDEDEDKDKDKDEERPAVQGPVNDLTSSDPPAPIRNKYGEFGNILLSNEEREQLIKRFGMHLTDVCIERMDSYMEQTGKCYNNCYAKLKNWISEEHEKVRHKRTNGSEKEHTYFTDKELEDYEHYARTQASDDFAKELEALVRAQEAREKNNKSLLSNIL
>NC_014825.1|WP_013483899.1|298473_299862_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MAVKKKAIIIPTVIALLAGGGLFACNTLSSAAKESMMANSKYSAIPAGENDLSKVISTTGNVIGNGTVDVTTKLTCPVSEVKVSLGDMVKEGDLLCEFDPTELQEEYDTLKKKMDNSDKKEKSDSSKNQRDLEAAKTKKEAALARAQRVIDKAEEVRDDAYEKYNSLCGEYNNAVNNNDPNYDYTGVFASLKQLEAGLSDLDDAVTTAKDGYNDTESQWNDTIQKLQDVIDGEAFDIGSDDQKTLDKLAEQIEQCKVYAPQSGIITALNVNEGSVPSSPSLMTIVNTDKTVIELTVKETDITKIAEGMKAKVTSKVLPGEEFAASITRIVNVVSTDVSAEGSSSGYKVEVTLDETNDSLLIGMTASVDITIEEVGEKLSVPYSGIIEEDGGDYVFVAEPADDEEGGYIARKKKVVKGAESDFYVEVKSGEVKSGDLIIEDPKGGDLPEVEDGARVKVNEKKK
>NC_014825.1|WP_013483909.1|313424_314771_+|DUF1727-domain-containing-protein
MSLKNTLTIWFGKLMVKTLRLLGRDAGNAPGLVLWELNKDCLKAFKVDCPIIAVTGTNGKTSVTNYLNHIFESTGKKIITNKQGNNLDTGITSLLLQNCDMKGRVKADYLVLEVDESHVPVIFSKMKLETLVLLNFFRDQLDRNGEVETLILKVKKFLETYEGNVVLNADDPNVSRLGLANPNNKNIYYFSVDRYAGATDKPYEVGEGKFCPSCGTELVYDYYQYSHVGKFRCPKCGFGDVKPYMTAKNVKLDVPSVEFEGEEYKISHNSIYYVYNLSAVYTAASLYNFDKKVLHETFEKFEVNNGRLEKFSVDGSELLVNLAKNPVGANMTLRVMNEHNDDKELLFVLNDNLADGHDVSWIWDINFSVFKDVSRVVTSGTRAYDIAIRIKCSGYDPDKIVVRPDLDDAMDEFFKNKGCKYAIANYTAIQPTRAAIKRYKAKAEGGQG
>NC_014825.1|WP_013483910.1|314770_315511_+|glutamine-amidotransferase
MEKLKILHMYPAMLDLYGDSGNVEILSYRCRMRGIETEVIKHDLGDRDTDFSGVDIVYLGGGADFEQQLLADDLLGLKDEIRKAYESGVYFLMICGGYQLMGQYYKDSNGKKIPGLGLFDYYTAASTNKRERCIGNIVVEADLSGEKYKVIGFENHGGQTTNVTSPFGKVLAGNGNEFSSTTEGYTEKNVTATYLHGPLLSKNPKLADHIISYCMTRKTGTDYVPAPINDKLEEDCRSQLFERLLK
>NC_014825.1|WP_013483911.1|315524_315695_+|hypothetical-protein
MFHFFRKRSADNEPALKKRIQAMKCRKINFVDDDFEGLCRDMKTGCKPLMRLKPVN
>NC_014825.1|WP_154662753.1|315713_317117_-|IS5-family-transposase
MNPDNRWVKKAEMIPWETIEAEYARLFPSHTGMPAKPLRMALGSLLIQKQYHYPDEELVEQIRENPYYQYFIGLPGYEDKIPFVPSLLVEFRKRLSEDVLNEINEMIIEYNSQQDNDDSDDVSGNGGQPDQQDPANDSEEKTENSGTLILDATCAPQNIKYPQDIELLNEVREKLEDMLCRVSDKYGFYRPRMYHQKARKDYLALAKCRKRGAKKIRKAIKKQLQYIRRDLGYIDNLIENNGVVLSVSDKELLDILMTVYDQQRYMFESNTHSVEDRIVSISQPYIRPIVRGKAKSPVEFGAKLDLSVDETGMCRIEKLSFNAYNESAVLKTAIENYKQRTGHYPERVLVDQIYRNRENISFCSGHGIRISGKKLGRPKNDADSKAEKKAAYKDNTDRIEVERKFSLAKRKFGLGLLLTKREDTTRASIVLSVIAMNIDRLAAMLLRFWKIVINIRFSYRQPVCRGF
>NC_014825.1|WP_013483913.1|317334_317505_+|hypothetical-protein
MGMLYSTEDFSENHIELLHFENERQTGKSDIYPVDTDTAVKLLAKVGIMIDLKKYG
>NC_014825.1|WP_037304146.1|317549_318248_+|endonuclease-V
MSEEEMQEKFRAFQEELSSRISCADSFHLSDIKTVAGIDLAYWQNENGDEQAVCCIVIIDFTTHEVIERQHFSGKINVPYMPGFLAFRELPLILETVKLLENIPDIYIFDGNGYLHPRHMGIASHASFYLDRPTFGIAKTYFRADKKTDYTEPSPESGSFTDIVIGGEVYGRALRTHTGVRPVFVSVGNNISLDTACNIALTLTDKESHIPIPTRLADLDTHVMREKLRSQN
>NC_014825.1|WP_013483915.1|318328_319324_-|LacI-family-DNA-binding-transcriptional-regulator
MSATIKDVAREAGVSVATVSRVLNGSCNVSEDSTEKVNDAIRKLKYSPNFLGRNLRKCETNVILCIMPTSEHSLYSKIVTGMQRYASKLGYDVITAVSDNTATAEARQMNMLFNRTVDGVVLLGTMYDAESLNHLAQNYDIALCCEGVPGADVLTVAVDDESAAFDAVTTLISKGHKDIAFVGTNSEAISSTARENGYKMALEKAGIPYREELVYRDSYEYNCGLDAMDYFAKLDKRPDAVFCVSDLLAIAVIHRGAELGITAGKDISVMGFDNISMCEMMLPTVSTVEQPCFKMGEMVIAKLIENIRSSHKDNKYYTVDHKVILRASTGD
>NC_014825.1|WP_013483916.1|319407_320094_-|SOS-response-associated-peptidase
MCTWFYAEKTALSPIISKAQKNPLAQTIMINLARPLAMSGNIRPTDMAAVFAPNKRGDMAVYPMIWGFTHDSSPKPLINCRVETAELKSVWKDSWFRRRCIIPASWYYEWGIPPMENGYRPIAGQNNIKKVKYAIQPEGAEITYLAGLYRFEEHRGVKVPVFAVLTREACAPVRDIHDRMPLIFRKEDLRDWVRPDSDPKSIAEKALTKMVVEKAVDYPEPVPEFMQI
>NC_014825.1|WP_013483917.1|320554_324178_+|leucine-rich-repeat-protein
MKSKRIVSAITALMLTASLMAGCSDRAADESSQAADTASSAAPSGNKDTDSDTTGDETTSDSETTDSETTDDENGLNVIDLSGEGTIADNIRLTSLSAVERGAFRETPSTRINVGTSAKARKWSDKKKEEKKKLTLMVYMVGSDLESKQAQKAATIDIGEMIYSGLDDKDVNLVIYCGGAQTWWIPGYPAGKNAYIEYKSKDSDIQGDNGAGINIYETDKKNMGKADTFGAFLKDVPEKYPADDYALICWDHGGGPVLGYGSDELNVDSKTKLGDSLTIAEMKDALDKSDFKKNKLKFVGFDACVMSSIEIADLWQDYAEYLVASADSEPGCGWNYEFLKDVKGDTDTTKICKGIIKTYFDYLSKISSSCYISDATLAAFDLSKTDSVKEAVGGVCKAMNDDLKNGDKKSYEKFLDGVHSYASFDLADLGTMVTSLSGSYADETKELKSAINDMVIDGTTTISNTCGMSVYFPLSNSTADLETSLIILKILGGGDYIKNDPLNSDYHALMSTLLSNTDVDVGTPSSKPDSSSSKKDEKSSSKAESSSSKKDEKSSSKAESSSSKKDEKSSSKAESSSSKKDEKSSSKAESSSSKKDEKSSSKAESSSSKKDESSSKPDNNGNSSASASALDKLDLTVVEKGAKSSDKEFKDDGCAYSKLPKEELANIRGVYYTVLKNVSMDEKKKSWAPYVLYIPAEVDNKGIAKMDLDPTIIGVVTDKDAEPNICLTKYLGDGNYRSSGTLSSTRDLADEYLRVNIQSHVDEKGNSAITGVTSNQNTDSGVPIASKDDIDLNEWLSFSSPVTGYAPDPKNPRKHFSEGTADTLGAAFSLLGDNFDVKACKPSDIPGEYAIQMSVFTIDGKEYCSNIGSWNIKDGNTEKLKEAKVDKGVLKFAVHDDYAELVKFEKSGKEEPKKLTVPDKFEGKKVTTVRDGAFSGTSPEEIVFPDSVEYIGYLSSGSSATKKVTLPKKLKSIPDEMFSYYTELESIEIPSTVESIGAFAFENSGLKEITIPKGVTYIGDGAFKECGSLDKITIESGSKNYIAEDNVLYTAGKKKLLAFTGRKHKEFTVPEGVTEINRYAFAGSFEQGLSFGNVSGDSDGLTKISFPKTLVKIGDFAFEGCTGFSEIILPDSLEYLGTGAFGHAFIQSSETELAVLKLGPNLKRIRSFAISGYKIKKLEVDKKNTCFRTDGKKLTSIDGSVEIKLTK
>NC_014825.1|WP_013483918.1|324318_325686_+|TrpB-like-pyridoxal-phosphate-dependent-enzyme
MATNIPYKTYLEESEMPKQWYNVRADMKNKPAPLLNPQTLKPMTAEELGVVFCDELVQQELNTTDAYIDIPEEIREFYKMYRPSPLVRAYCLEKALGTPAKIYYKFEGNNTSGSHKLNSAIAQAYYAKKQGLKGVTTETGAGQWGTALSMACSYFDLDCKVFMVKVSYEQKPFRREVMRTYGASVTPSPSETTNVGKKILAEHPGTSGSLGCAISEAVEVAVGTEGYRYVLGSVLNQVLLHQSVIGLESKAAFEKLGVKPDIIIGCAGGGSNLGGLIAPFMGQKLRGEADYRFIAVEPASCPSLTRGKYAYDYCDTGMVCPLAKMYTLGSGFIPSANHAGGLRYHGMSSTLSQLYDDKLMEAVSVEQTKVFEAAQQFARVEGILPAPESSHAIRVAIDEALKCKETGEEKTIFFGLTGTGYFDMVAYQKFNDGLMTDYIPTDDDLAKGFAGLPKV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014825_1	1.1\|312928\|42\|NC_014825\|CRISPRCasFinder	312928-312969	42	NC_014825	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence	312928-312969	0	1.0
NC_014825_1	1.1\|312928\|42\|NC_014825\|CRISPRCasFinder	312928-312969	42	NC_014825	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence	313020-313061	3	0.929

1. spacer 1.1|312928|42|NC_014825|CRISPRCasFinder matches to NC_014825 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence) position: , mismatch: 0, identity: 1.0

agggtcgccgacacgtcaccaacattgttatgacgggcagta	CRISPR spacer
agggtcgccgacacgtcaccaacattgttatgacgggcagta	Protospacer
******************************************

2. spacer 1.1|312928|42|NC_014825|CRISPRCasFinder matches to NC_014825 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence) position: , mismatch: 3, identity: 0.929

agggtcgccgacacgtcaccaacattgttatgacgggcagta	CRISPR spacer
cggggcgccgacacgtcaccaacattgttatgacgggcagtt	Protospacer
 *** ************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

69160 : 171469

Acidithiobacillus_phage(14.29%)

transposase,integrase,protease

attL 67676:67692|attR 176531:176547

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
67676:67692	attL	NA	NA	NA	NA
WP_013483722.1\|69160_70432_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.3e-123	55.7
WP_013483723.1\|70443_71034_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.7e-53	50.3
WP_013483724.1\|71115_72396_-	trigger factor	NA	NA	NA	NA
WP_013483725.1\|72468_73179_-	metallophosphoesterase	NA	NA	NA	NA
WP_013483726.1\|73271_73445_+	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_028504380.1\|73491_73716_-	hypothetical protein	NA	NA	NA	NA
WP_013483728.1\|73720_75214_-	threonine synthase	NA	NA	NA	NA
WP_013483729.1\|75261_75639_-	YraN family protein	NA	NA	NA	NA
WP_154662868.1\|75613_76291_-	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	1.5e-26	43.8
WP_013483731.1\|76229_77126_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_013483732.1\|77163_77730_-	signal peptidase I	NA	NA	NA	NA
WP_013483733.1\|77732_78584_-	signal peptidase I	NA	NA	NA	NA
WP_013483734.1\|78782_79127_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_013483735.1\|79299_80007_-	DUF2344 domain-containing protein	NA	NA	NA	NA
WP_013483736.1\|79981_81847_-	TIGR03960 family B12-binding radical SAM protein	NA	NA	NA	NA
WP_013483737.1\|82027_84733_-	endo-1,4-beta-xylanase	NA	NA	NA	NA
WP_013483738.1\|85654_86005_-	DUF1667 domain-containing protein	NA	NA	NA	NA
WP_013483739.1\|86008_87268_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_154662880.1\|87270_88668_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_013483741.1\|88948_89359_+	transcriptional repressor	NA	NA	NA	NA
WP_013483742.1\|89413_90400_+	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013483743.1\|90471_91191_+	metal ABC transporter ATP-binding protein	A0A2H4UUX5	Bodo_saltans_virus	6.8e-09	25.3
WP_013483744.1\|91183_92086_+	metal ABC transporter permease	NA	NA	NA	NA
WP_154662882.1\|92139_92691_+	hypothetical protein	NA	NA	NA	NA
WP_013483746.1\|92785_93151_-	dockerin type I repeat-containing protein	NA	NA	NA	NA
WP_013483747.1\|93544_94129_-	cyclase family protein	NA	NA	NA	NA
WP_013483748.1\|94896_96654_+	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_050793336.1\|96891_97641_-	GTP pyrophosphokinase family protein	F8K9M7	Nitrososphaera_phage	1.0e-07	31.5
WP_013483750.1\|97789_98590_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_154662878.1\|99162_100263_-	hypothetical protein	NA	NA	NA	NA
WP_154662881.1\|101964_102177_-	DUF4869 domain-containing protein	NA	NA	NA	NA
WP_080557325.1\|102468_102666_-	mobility-associated LCxxNW protein	NA	NA	NA	NA
WP_013483755.1\|102662_103409_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	8.1e-29	33.6
WP_013483756.1\|103398_104958_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_050793333.1\|105716_106067_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013483758.1\|106330_107935_-	recombinase family protein	D7RWL2	Brochothrix_phage	2.2e-15	23.7
WP_013483759.1\|108276_108816_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_154662895.1\|108896_109526_+	esterase	NA	NA	NA	NA
WP_013483761.1\|109522_110113_+	nitroreductase	NA	NA	NA	NA
WP_013483762.1\|110145_110862_+	acyl-ACP thioesterase	NA	NA	NA	NA
WP_013483763.1\|110875_111718_+	DUF2262 domain-containing protein	NA	NA	NA	NA
WP_013483764.1\|111758_112244_+	hypothetical protein	NA	NA	NA	NA
WP_013483765.1\|112814_113348_+	3'-5' exonuclease	A0A0K2SUJ2	Clostridium_phage	3.0e-09	30.4
WP_013483766.1\|113468_113657_+	DUF4314 domain-containing protein	NA	NA	NA	NA
WP_013483767.1\|113789_114887_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_043551207.1\|115217_115850_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_013483433.1\|115966_116971_-\|integrase	site-specific integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	8.1e-08	22.3
WP_013483768.1\|116963_117944_-\|integrase	tyrosine-type recombinase/integrase	A0A0E3Y5J2	Fusobacterium_phage	8.7e-07	25.3
WP_013483769.1\|117940_119173_-\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	2.5e-11	27.3
WP_043551190.1\|119391_120291_+	hypothetical protein	K4I413	Acidithiobacillus_phage	4.6e-39	34.1
WP_154662911.1\|120190_121759_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	1.4e-67	34.0
WP_080557325.1\|122253_122451_-	mobility-associated LCxxNW protein	NA	NA	NA	NA
WP_043551208.1\|122447_123020_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	4.7e-21	36.6
WP_013483772.1\|123238_123541_-	IS66 family insertion sequence element accessory protein TnpB	S5WJH4	Leptospira_phage	8.0e-12	44.3
WP_013483773.1\|123537_123864_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_013483774.1\|124052_124820_+	ATP-binding protein	NA	NA	NA	NA
WP_013483775.1\|124819_125014_+	mobility-associated LCxxNW protein	NA	NA	NA	NA
WP_013483332.1\|125110_125794_+	helix-turn-helix domain-containing protein	A0A0C5AJ29	Paenibacillus_phage	7.4e-37	42.8
WP_013483331.1\|125835_126684_+\|transposase	IS3 family transposase	A0A0C5AC89	Paenibacillus_phage	4.8e-78	65.8
WP_013483776.1\|127636_128059_+	hypothetical protein	NA	NA	NA	NA
WP_013483777.1\|128131_129454_-	NYN domain-containing protein	NA	NA	NA	NA
WP_013483778.1\|129460_129715_-	hypothetical protein	NA	NA	NA	NA
WP_013483779.1\|129859_131251_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_013483780.1\|131247_131577_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_013483781.1\|132120_132744_+	DNA primase	S5M810	Pseudoalteromonas_phage	4.8e-11	44.0
WP_013483783.1\|132851_133244_+	hypothetical protein	NA	NA	NA	NA
WP_013483784.1\|133236_133422_+	hypothetical protein	NA	NA	NA	NA
WP_013483785.1\|133421_133667_+	HU family DNA-binding protein	NA	NA	NA	NA
WP_013483786.1\|133942_134131_-	hypothetical protein	NA	NA	NA	NA
WP_013483788.1\|134717_134951_+	hypothetical protein	NA	NA	NA	NA
WP_013483789.1\|135098_136622_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	1.5e-77	36.7
WP_013483790.1\|136624_137500_+	recombinase	A0A2K5B2B2	Erysipelothrix_phage	7.3e-05	30.1
WP_013483791.1\|137484_139122_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	5.2e-97	43.0
WP_013483792.1\|139351_140431_-\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	1.5e-28	31.1
WP_013483793.1\|140669_141587_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013483794.1\|141590_142535_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013483795.1\|142624_143530_+	hypothetical protein	NA	NA	NA	NA
WP_013483796.1\|143548_144640_+	hypothetical protein	NA	NA	NA	NA
WP_013483797.1\|144661_145534_+	hypothetical protein	NA	NA	NA	NA
WP_013483798.1\|145574_146627_+	hypothetical protein	NA	NA	NA	NA
WP_013483799.1\|146703_156981_+	hypothetical protein	NA	NA	NA	NA
WP_013483800.1\|157372_157813_+	DUF4869 domain-containing protein	NA	NA	NA	NA
WP_013483801.1\|157817_158798_+	hypothetical protein	NA	NA	NA	NA
WP_013483802.1\|159388_159766_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_013483803.1\|159759_160116_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	6.1e-19	45.5
WP_013483804.1\|160380_160728_+	hypothetical protein	NA	NA	NA	NA
WP_013483805.1\|161169_162681_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	1.3e-54	30.1
WP_043550632.1\|162670_162883_+	hypothetical protein	NA	NA	NA	NA
WP_043550630.1\|162886_163210_+	hypothetical protein	NA	NA	NA	NA
WP_162145126.1\|163302_163638_+	hypothetical protein	NA	NA	NA	NA
WP_080557327.1\|163555_164914_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	4.5e-46	30.4
WP_154662914.1\|165279_165453_+	hypothetical protein	NA	NA	NA	NA
WP_013483806.1\|165506_165701_-	mobility-associated LCxxNW protein	NA	NA	NA	NA
WP_013483807.1\|165700_166468_-	ATP-binding protein	NA	NA	NA	NA
WP_154662845.1\|166464_167370_-	hypothetical protein	K4I413	Acidithiobacillus_phage	2.0e-42	35.5
WP_013483808.1\|167510_168743_+\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	2.5e-11	27.3
WP_013483768.1\|168739_169720_+\|integrase	tyrosine-type recombinase/integrase	A0A0E3Y5J2	Fusobacterium_phage	8.7e-07	25.3
WP_037304908.1\|170836_171469_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
176531:176547	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_014833

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_014833_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_1

14874-14956

Orphan

Consensus_repeat	Method
AAATGTTCCACGTGGAACAATTTATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014833_1

>merge|NC_014833|1|14874-14956|CRISPRCasFinder
AAATGTTCCACGTGGAACAATTTATATTTTGTCTGTTTAGAATATCATTCCGAACAAAAATGTTCCACGTGGAACATTTTATA

>NC_014833|1|1|14874-14956|CRISPRCasFinder
AAATGTTCCACGTGGAACAATTTATA	TTTTGTCTGTTTAGAATATCATTCCGAACAA
AAATGTTCCACGTGGAACATTTTATA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_013496771.1\|4753_5101_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013496781.1\|17219_19868_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NC_014833.1\|WP_050793244.1\|12648_12945_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013496788.1\|27181_29545_+\|CotH-kinase-family-protein	unknown	unknown	gnl\|CDD\|378045
NC_014833.1\|WP_013496776.1\|8814_11325_+\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
NC_014833.1\|WP_013496772.1\|5122_5389_+\|DUF370-domain-containing-protein	unknown	unknown	gnl\|CDD\|377201
NC_014833.1\|WP_013496787.1\|25330_26593_+\|DUF1015-domain-containing-protein	unknown	unknown	gnl\|CDD\|377633
NC_014833.1\|WP_037305241.1\|19955_20813_+\|shikimate-dehydrogenase	unknown	unknown	gnl\|CDD\|223247
NC_014833.1\|WP_013496785.1\|23248_23935_+\|PHP-domain-containing-protein	unknown	unknown	gnl\|CDD\|213987
NC_014833.1\|WP_157865465.1\|12907_13417_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NC_014833.1\|WP_013496783.1\|21073_22243_+\|cellobiose-2-epimerase	unknown	unknown	gnl\|CDD\|238153
NC_014833.1\|WP_013496786.1\|24065_25286_+\|glycoside-hydrolase-family-5-protein	unknown	unknown	gnl\|CDD\|365907
NC_014833.1\|WP_013496777.1\|11830_12586_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|236669
NC_014833.1\|WP_013496773.1\|5392_7381_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl\|CDD\|235542
NC_014833.1\|WP_013496780.1\|16190_17105_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_014833.1\|WP_013496774.1\|7405_8110_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379272
NC_014833.1\|WP_013496775.1\|8110_8695_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013496778.1\|13822_14689_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_014833.1\|WP_013496779.1\|15103_15883_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NC_014833.1\|WP_013496784.1\|22266_23199_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_013496787.1\|25330_26593_+\|DUF1015-domain-containing-protein	gnl\|CDD\|377633	pfam06245, DUF1015, Protein of unknown function (DUF1015). Family of proteins with unknown function found in archaea and bacteria.	5.1998e-96
NC_014833.1\|WP_013496781.1\|17219_19868_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NC_014833.1\|WP_013496779.1\|15103_15883_+\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	8.66328e-79
NC_014833.1\|WP_013496776.1\|8814_11325_+\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NC_014833.1\|WP_013496772.1\|5122_5389_+\|DUF370-domain-containing-protein	gnl\|CDD\|377201	pfam04025, DUF370, Domain of unknown function (DUF370). Bacterial domain of unknown function.	7.98196e-06
NC_014833.1\|WP_037305241.1\|19955_20813_+\|shikimate-dehydrogenase	gnl\|CDD\|223247	COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and metabolism].	2.23893e-64
NC_014833.1\|WP_013496785.1\|23248_23935_+\|PHP-domain-containing-protein	gnl\|CDD\|213987	cd07432, PHP_HisPPase, Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase. HisPPase catalyzes the eighth step of histidine biosynthesis, in which L-histidinol phosphate undergoes dephosphorylation to produce histidinol. HisPPase can be classified into two types: the bifunctional HisPPase found in proteobacteria that belongs to the DDDD superfamily and the monofunctional Bacillus subtilis type that is a member of the PHP family. The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. The PHP domain of HisPPase is structurally homologous to other members of the PHP family that have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel.	5.86979e-19
NC_014833.1\|WP_157865465.1\|12907_13417_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	9.00368e-22
NC_014833.1\|WP_013496783.1\|21073_22243_+\|cellobiose-2-epimerase	gnl\|CDD\|238153	cd00249, AGE, AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is structurally and mechanistically distinct from the other four types of epimerases. The AGE domain monomer is composed of an alpha(6)/alpha(6)-barrel, the structure of which is also found in glucoamylase and cellulase. The active form is a homodimer. The alignment also contains subtype III mannose 6-phosphate isomerases.	1.90412e-39
NC_014833.1\|WP_013496786.1\|24065_25286_+\|glycoside-hydrolase-family-5-protein	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	2.85287e-71
NC_014833.1\|WP_013496777.1\|11830_12586_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	1.95585e-09
NC_014833.1\|WP_013496773.1\|5392_7381_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl\|CDD\|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0
NC_014833.1\|WP_013496774.1\|7405_8110_+\|hypothetical-protein	gnl\|CDD\|379272	pfam13571, DUF4133, Domain of unknown function (DUF4133). Based on Bacteroides thetaiotaomicron gene BT_0094, a putative uncharacterized protein as seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2231), It appears to be upregulated in the presence of host or vs when in culture.	0.00943694
NC_014833.1\|WP_013496788.1\|27181_29545_+\|CotH-kinase-family-protein	gnl\|CDD\|378045	pfam08757, CotH, CotH kinase protein. Members of this family include the spore coat protein H (cotH). This protein is an atypical protein kinase that phosphorylates CotB and CotG.	4.1497e-27
NC_014833.1\|WP_013496778.1\|13822_14689_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.55999e-85
NC_014833.1\|WP_013496780.1\|16190_17105_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.06049e-79

>NC_014833.1|WP_013496778.1|13822_14689_-|ParB/RepB/Spo0J-family-partition-protein
MNKLTDFITKAFVEIREETVEEIPDTGKLLEIGTGDIRPNPSQPRRHFSPEELTSLAKSITANGIIQPLTVRQTENDFELISGERRLRAAKLAGLKTVPCILIEADKKRSAVLALLENIQRSDLNCFEEAAAINKLIESGEITREKISIKLGMARSTIANKLRLLKLTDEEQQLMIEKGLTERHARALLRVADEDRRKEILAKTINGSWTVDTLEKYIDRLERQELKKTSYEKRAVMLKDVRLFFNSVNKALEVMKLAGVEATAKRIDREDHIEYTIVIKNTADEKSV
>NC_014833.1|WP_157865465.1|12907_13417_+|helix-turn-helix-domain-containing-protein
MLISSSICPYIGESIDVASYFRLIADCYYRRNNLQTAGFLIKALLTEVFSENGKQEESGIVHYRELLDLRRRIYAQPSEDWSVEKMAQLISVSEPYLHLLYKKAFGITCNADVINSRIESAKHFLAYTDRTVEDIAFTCGYKNAVHFSRQFKQATTLSPSEWRKNNSVV
>NC_014833.1|WP_050793244.1|12648_12945_+|hypothetical-protein
MFYINRMGCSCRHDGNFVLDQPRGYEGHLMLFVKTKAVFVINGVTINVEPNTFIIYDKNSPQYYKACDDEYINDWIQFECSEDISSGVDIKFDMPIYR
>NC_014833.1|WP_013496777.1|11830_12586_+|zinc-ribbon-domain-containing-protein
MPNCPKCNFPYEEGQAFCNTCGCKLPVSIKQKVCPVCGNTLLENTKVCNICGTPVNESQDTTAAEELAKQQEALKNPTMDAVEIPVITDDMLQNEEPNKADMPTMDSIFMPGQEPAPKSVQTAKPAPAPAPIPTPAPAPIPQNQFQQTNQYQQPVQPQNQFQQTNQYQQPMQPQNQFPQNNVPINNAPINNVPQNGVKPGKKSFAPLILIILIIAVILVDIFVLFPEQIFKKKDDSAKKNAAVITVTDDIF
>NC_014833.1|WP_013496776.1|8814_11325_+|DNA-gyrase-subunit-A
MDEYNLLNQDVESIMKESFLQYSMAVIVSRALPDVRDGLKPVHRRILYTMHENGLTPDQAYRKCADTVGSVLGRYHPHGDASVYDALVRLAQSFSLRYPLVDGHGNFGSVDGDPPAAYRYTEAKMAKMAVNMLTDIKKDTVDFQSNYDDRLQEPCVLPSRFPNILCNGAVGIAVGMATNIPPHNLHEVIEGMKIVIQNPDCTLDELMQAIKGPDFPTGGIIMGRSGIRAAYGTGRGKITLRSKTSIEEIKGRNCIVVTEIPYMVNKAKLVESIAGLVKDKRVEGIHDLRDETSRDGMRIVIELKKDANPQVVLNKLFSYTQLQDSVGVILLALVNGIPKILTLKQILQEYIDFQVSVIRRRTEFDLKKAKEREHILQGLVIALDNIDEVIEIMKNSKSIPEAKQKLCTRFGLTDVQADHIAQMTLGRLTGMERQKIIDELAEITATVADLEDILANEQRVFDIIIEEVEAIQEKFGDERRTQIENVSGEVDIEDLIPVEESVVTYTNVGYIKRMPISVYKAQNRGGKGVTGMKQREDDCITEMSVCSSHDNILFITTKGIAYKMKCYELPEGSKASRGVNIKNLLELSDDNLIAAMIKVEDFDDDKYIVMVTKRGKIKRTPLSAYKNVRKNGLIAIGLDEGDEIAGVRLTGGQNELLIATHNGMAIRISENDVRVMSRTAHGVRAIKLREGDYVVSMARIREGATVLTVSETGLGRRVALENYPIRHRGGHGVLNYKNGEVCGIKVVDEEDDIIMISSDGIVIRLRACDISVMGRYSRGVRLMKVAGENKVVTFTRTEHDDEAEIAEVEKASEEDILKAQEEEKAEVLEEDTVAED
>NC_014833.1|WP_013496775.1|8110_8695_+|hypothetical-protein
MRNRIKNRGIALLLIGIVFVLMGVFLAVHYASFIFLGKTVDLNEVLKNGEELPQGEFVSYTCEYPIGNYCELQTYINGIIPTPSKSQLYAMMDEYDGKGLIFSAKVNNKNKIKEFNRVVNGQTESVTVVGSLDTIVNYDASQYLKNSCSNIEGDVVLTEFVIDSTKTRFSQIALCIFAIALGVFCLVTFIKKKR
>NC_014833.1|WP_013496774.1|7405_8110_+|hypothetical-protein
MEIDISKNGGNTEETVEKVERFYERDVLDKKEEDIPNTAEEKEFVPAGEPLTGFEYNIKNEEEEEAFTVFQKKYVYKRNWIVTALFSVVAIMFMISIARDPGVYLNWVLCFVCLVMIFTTWFNTFRIKKYLMKALASLEDDKYRFTLYDDCFKIETVFTEEEMQAEDFVPVKPRIVRFEDISLNIIENARLFIIILRKETIYVLSKRVIKEKDQTLLRDKLKEVLGEDYEVSEN
>NC_014833.1|WP_013496773.1|5392_7381_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MDNDNIKEVEIVDTESISQIDKSNNYDENQIEVLEGLEPVRVRPGMYIGSTGPKGLHHLVYEIVDNAIDEALAGYCTEIIVDILPGDVIRVVDNGRGIPTGIHPKEGISAATVVYTVLHAGGKFGGGGGYKVAGGLHGVGASVVNALSEYLELTVYDGKNVHFQRFDRGHYSEPLKIIGETDKTGTEVKFKPDPEIFQETTTFDYEILLKRLREQAFLNAGIKIVFSDLRNAEKPISEVLHYEGGIRQFVEHIHKTRGVEPLSEDVIYINGVEDDMFAEIALQYNDTYNEIILSFANNIHTPDGGSHEMAFKSALTKILNDYGKAHNLIKDNDDALMGEDCREGLTAIVSVKLTNCEFEGQTKGRLGNPEVRPFVDKMLKEKLRNYLEENPAVAKAIFDKSIQAQKAREAAKRARELTRRKSVLESASLPGKLADCSERDMSMTEIYIVEGDSAGGSAKEGRDRRYQAILPLWGKMLNVEKARIDKVYGNEKLMPVVTALGTSIGDDFDISKLRYGKVIIMADADVDGSHIRTLLLTFFFRFMRPLIEEEHVFIAQPPLFKVERNKKVRYAFTDEERDKYIDELSDGGKLKVAVQRYKGLGEMDPEQLWETTMDPERRTMIKVTMEDAVKADEIFTILMGDKVGPRKEFIEKNAEYVKDLDV
>NC_014833.1|WP_013496772.1|5122_5389_+|DUF370-domain-containing-protein
MYLHIGNDFMVNSKNIVGIFDLENSSTSAITRDYLGSAEKNKHVTYCTYELPKSFVVCFDDKTLEERVYISQLSCATLLKRYKSSRRY
>NC_014833.1|WP_013496771.1|4753_5101_+|hypothetical-protein
MDEIREVQVVKCDKGHLYAANEYKTCPYCKIYEKKKEEEAQRIRAVKARELHVNTRWENFRLWFDDHFGTLFSVIWTTIKIITAPLRLIAKSGYENQHGEWSRGTSYSEQHRWHR
>NC_014833.1|WP_013496779.1|15103_15883_+|ParA-family-protein
MGKIIAVSNQKGGVGKSTTVCNLAAVFGARGEKVLIIDFDPQGNTTTSYGIQKRSIRNTIYDVLMGDCSLFEAVCATAFRGVSVVPTTQELAGASVQLMSMENRASQLKEKLSEARNFYDHIFIDCPPTLDMLTINALVAADSVLIPLQCEFLSLEGLVELHSTIDRVKQAWNKSLVIEGILFTMCVDRYKITGQIVSEVKKHFPKEVFTTSIPRNVALSEAPSFGQPAIYYDKKAKGSKAYEELAKEMLKRDKKRKAK
>NC_014833.1|WP_013496780.1|16190_17105_+|ParB/RepB/Spo0J-family-partition-protein
MGKKNRMGSGLDMLFAENTQPETVSSEQESNDSVAMVKITLLEPNKDQPRSLFDDDKLSELADSIKENGVLQPILARPLDNGGYQIVAGERRWRASRLAGLTEVPVYIKELDDKQTMQMALIENIQRQDLSPVEEAKAYKNLMDTYNMTQQQVAESVGKSRSAVANSLRLLELTATVRDMVDNGELSVGHAKVLSGVDDDKQCILAERIISEGLSVRQLEDEIKKLALSETKRSDDEKASIRKNSIKKDRPFLYEFMMSVNAVSDYNVKAKEERGGGVKVELKIPKEVDAETLLSKLAVLLTDE
>NC_014833.1|WP_013496781.1|17219_19868_+|preprotein-translocase-subunit-SecA
MGLLDKLFGNYSKKELAKIEPIKNKVLELEEKYAAMSDTELGEQTALLKSKVDDASGLDDVLPDALAVCREAAWRVLGKKPYPVQIIGAIVLHQGRIAEMKTGEGKTLVACLAAYSNSLTGKGVHVVTVNDYLAKFQSEEMGKVFNFLNTSIGCVLSGMDKSAKRVAYNCDITYGTNSELGFDYLRDNMVIYKKDKVQREHAFAIVDEVDSILIDEARTPLIISGQGDKSTELYGLADKFAKTLKPVTVIEMDDKIDNDTLDGDYIIDEKAKTATITKSGVKKAEKAFHVDNLMDAENMTLAHHINQALKANGVMKEGVDYIVRDGEVLIVDEFTGRVMDGRRFNDGLHQAIEAKEGVEVKRESKTIATITYQNYFRLYNKLSGMTGTALTEEDEFREIYKLDVIEIPTNRPVIRKDHPDVVYKTEAGKFDAVIDKIVECHEKGQPVLVGTVSIEKSEYLSKLLKKKGVQHNVLNAKYHDREAMIVAQAGKFGAVTIATNMAGRGTDITLGGNAEYLSLAALQKEGYTEEQAVEAASYSNTDDEEILTARKKYRELYKKFDEEVKEKAEKVREAGGLYIIGTERHESRRIDNQLRGRSGRQGDPGESTFFLSLEDDLMRIFGGDRITGMMDTLNVDEHTPIQSRMLSSVIESSQKKIEGRNFNIRKNVLNYDDVMNTQREIIYSQRQMVLDGEDLHEYIVHMIKDFVDDSVNMYVQGDIADDWNLVGLKERLNGLFTTEDDFNYTAEEMDELTREDIVNTLQERAEKLYDDRERELGEELLHEIERVCLLKVVDTKWMDHIDDMEELKKGIGLRSYGQKNPVVEYRMEGMDMFDAMIESIREDTVRMLFTIKVRQQIAPQRQEVLKPMENHHNMTLRKREKN
>NC_014833.1|WP_037305241.1|19955_20813_+|shikimate-dehydrogenase
MERKYALLGESLKHTMSPPIHRRLFELKNREFTYEIIELPPEALEGHAEYLKALAGFNITIPHKIGIIPYCDKLADSAKRYNSVNCVDNKDGVHTGYNTDCDGFLATIRAMGADLGGKVLLIGCGGVGRMMAIEAALAGADLVIAVLESDIPLAEQAKKEIIAMKSDAKVTIVKNTEIDTSVSYDLLMNACPVGMYPRVEGCPVSDEVIEASKAVFDVIYNPRETVLIRKARALGKKAAGGMAMLVWQAVKAHEIWDSDTYTDSEVQAIIEEMELQVEKDFPIGK
>NC_014833.1|WP_013496783.1|21073_22243_+|cellobiose-2-epimerase
MMISEIRQELTDHIIPFWNKLRDDENGGFYGYLSYGLELDKKADKGVILHSRILWFYSNAYMTLGGDELLDNAKHAYEFIKNNCIDYEYGGVYWMMDFEGKPADTMKHTYNIAFAIYALSSYYRASGDKEALALAYRLFEDIEKNTLDEYGYREAFDRQWRLVDNEALSENGLKADKTMNAILHLIEAYTELYKADGNEKVADRLKFQLGQMRDIVYTPDTNALKVFFDTAFNLVGDIHSYGHDIEATWLMDRACDVLGDEDLKKQFAEMDLKISHNIQDIALEDGALNNERDKNEIDKTRVWWVQAEAVVGFINAYQHSGDEKFLESAKSVWENIKEYIIDKREGGEWYSEVTFDHTPHDYKETVGPWKCPYHNGRMCMEVITRGVDI
>NC_014833.1|WP_013496784.1|22266_23199_+|hypothetical-protein
MEKAVKLLHRTLITLCIFILGGSLIYYLTKWGSLPDEPGIHFGSDQEFDVYASKVYGFYPHLMSGITIGIAAFSGWLIGRKNTGLNISEKGERLFKAEIMLTIDVIALLVTLTFLEWTMAVSHQRALGNIALVLISAAFIAGAVGIIAEIVTAVKFRKKNEPAKGTGTFHRSCRIAAWLITGFSVILLIFIWERLPNDDVTDQYHGLAYFANFDAYLAKWLLLVPSAVVIAILAVLEVISVRAMKKDSKALVRFTDRLKLINGLFFFWWDLMLMSEAEIGAVSVCIYAGLTILYAALYIFHKKEYNHTGA
>NC_014833.1|WP_013496785.1|23248_23935_+|PHP-domain-containing-protein
MYKYETHLHTAETSACASATGAEQARRYKAEGYNGIFVTDHFFNSNTTVPRDISWDEKVMLYCKGYENAKAEGDRIGLKVFFGIEYTYQGADILVYGLDKRWLLAHPDCDRDFYQFCYDARAEGALLIHAHPFREADYLREIKLLPKWVDGVEVYNSGNSKEVYNERAEWYAKQYGFRMTAGTDNHHLDKPSERLAGIISEVRFECAEDYAGAFFSGRVIPLYPKERL
>NC_014833.1|WP_013496786.1|24065_25286_+|glycoside-hydrolase-family-5-protein
MNSKKIGAMIAAAVLSLSVMTACGNKEDSSKADKKSSTAVENSAADESETENVPVSQTHTNDTMTVTSAKDLVAKMTNGWNLGNTMDATGEGLGSEVSWLPLKVTTNKYMIDMLPEAGFNVLRIPVSWGNHIIDDKYTIDPAWMDRVQEIVNYGIDNGLYVILNTHHEEWYMPKPSEKDGDIEEIKAVWAQIADRFKGYDEHLIFEGLNEPRLRGEGAEWTGTSEAREIINEYEKAFVETVRASGGNNGDRCLMITGYAASSAYNNLSAIELPEDSDKLIISVHAYLPYSFALDTKGTDKYDPEDTAIPELFEHLNELFISKGIPVIVGEFGTMNKENTEDRVKCLEDYLAAAAKYDIPCVWWDNYARIGNGENFGLMNRADLEWYFPDLIETFKTYAEKDPASAE
>NC_014833.1|WP_013496787.1|25330_26593_+|DUF1015-domain-containing-protein
MSTAFRGADILLPKDTDMKKWAVVACDQYTSEPEYWDRVEKYVGDAKSAYDLILPEVYLEQPGVDYRIDKIHRTMNEYIEKGVFEEYKDAMIYIERVQSDGRVRAGLIGGIDLEQYEYYKGSESQVRATEATVIERIPPRIKIRKGAPVELPHIMILIDDVKKRIIEPLADKKDEFTKLYDFDLMEGGGHITGWLLDKENEEIVLSHLEQFSKQEAFERRYGIKGRQPLTYAMGDGNHSLATAKEFYETLKRAEPAADLSGHPARYALVELVNLHSPALEFEAIHRIVTEVDADKLVDELTKKLELSDKESEQGFVIVRNGEEKKVYVHAPSSKLTVGSLQNFLDNYTKEFGGKTDYIHGADVVKELSKKKNSIGFLLPDMGKDELFPTVIEDGALPRKTFSMGHAADKRFYVEARRIIK
>NC_014833.1|WP_013496788.1|27181_29545_+|CotH-kinase-family-protein
MKKEYDKKCIAVLSAVGLAVTGIVIACVILLSPKKLVISEICADNDGKFKEASHRDSKGKLCDWVEIYNPNDKEVSLKDYTIVREDGKECAVSGGSVPAHGYALIYCTKNGFDDSDIPWVDIKIPKGEEHTISIKSGSKVIDSLTAEPTPEGFTVCSGEDGAYITVPTPCSENSRDKKASQVVFSEESGFYPKGFMLEMTAANSAGIYYTTDGTDPRTSDTAEIYSKPLEVKDRSGEKNVLSAIDPMKIQLQYRVGKVKLPKDEDVDKGTVIRACARNTDGGWGKVSTASYFVGFSTEDHSSMPVISMVTDPAALYDHETGIYVRGKVYEDYYPTEPDHLYNGSIPANYNQRGKEWERPCCLQFFESDGSLVFTQDAGMRIQGGWSRADYQKSFRFFARSDYGSKKFGYSFWQGLETADGRDDDSFSTFVLRNGGNDSNYLKFKDIMIQDMASCLLPATQSGRPCVLFIDGEYWGMYVLQEDYSQEYFARHYGVDEDSVAIYKNDELDEGMDPDEISYSNMQKFISESDMSIDDNYRRACELMDMDCFIDYCAVEMYIFNDDWPQNNYGCWRSTDGSIYGDGKWRFFLFDTESCACHYNMKSLETDIFEYLEKKQKKPLNSMILSLLENEEFRSKLTTRLMDMGNILYTAERTSSFEKRYEAEYLPEMYAYFLRFPTYRTVERSSMGMISRMSKFFDGRQQKLIKDLSHRYTLGRAKTVKVTSDKDITLNGLSIQSGFEGRYFNNCELILKADSEVTWTVKQNGNTTEVNDSKLVIKMTGDTEIKAE

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Crispr_ID: NC_014833_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_2

246698-246810

Orphan

Consensus_repeat	Method
TGACGGAGTCAGAGTCCGTTGCCTTACCGCTTGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014833_2

>merge|NC_014833|2|246698-246810|CRISPRCasFinder
TGACGGAGTCAGAGTCCGTTGCCTTACCGCTTGGCGACGCCCCAGTATGGTTGGGATAGATGGATTCGAACCATCGAATGACGGAGTCAAAGTCCGTTGCCTTACCGCTTGGC

>NC_014833|2|2|246698-246810|CRISPRCasFinder
TGACGGAGTCAGAGTCCGTTGCCTTACCGCTTGGC	GACGCCCCAGTATGGTTGGGATAGATGGATTCGAACCATCGAA
TGACGGAGTCAAAGTCCGTTGCCTTACCGCTTGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_013496994.1\|254789_256712_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_014833.1\|WP_013496977.1\|237223_238117_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_014833.1\|WP_013496978.1\|238131_239016_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NC_014833.1\|WP_013496979.1\|239108_240401_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270452
NC_014833.1\|WP_013496980.1\|241490_242030_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|131898
NC_014833.1\|WP_154662739.1\|248867_249923_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_014833.1\|WP_013496990.1\|250989_251859_-\|GPR-endopeptidase	unknown	unknown	gnl\|CDD\|237076
NC_014833.1\|WP_013496981.1\|242076_242748_-\|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO	unknown	unknown	gnl\|CDD\|376698
NC_014833.1\|WP_013496986.1\|247103_247595_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NC_014833.1\|WP_013496993.1\|253007_254789_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_014833.1\|WP_013496985.1\|245306_246164_-\|NPXTG-anchored-protein	unknown	unknown	gnl\|CDD\|368289
NC_014833.1\|WP_013496984.1\|244675_245191_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227816
NC_014833.1\|WP_013496982.1\|242823_243183_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013496992.1\|252555_253011_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NC_014833.1\|WP_013496989.1\|250483_250933_+\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|107228
NC_014833.1\|WP_013496976.1\|236103_237063_-\|2-dehydropantoate-2-reductase	unknown	unknown	gnl\|CDD\|224805
NC_014833.1\|WP_013496987.1\|247699_248821_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NC_014833.1\|WP_013496991.1\|252081_252333_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|376586
NC_014833.1\|WP_013496983.1\|243307_244327_-\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|181535
NC_014833.1\|WP_013496995.1\|256867_257758_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_013496994.1\|254789_256712_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.35761e-169
NC_014833.1\|WP_013496977.1\|237223_238117_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.23726e-76
NC_014833.1\|WP_013496978.1\|238131_239016_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	5.81617e-74
NC_014833.1\|WP_013496979.1\|239108_240401_-\|extracellular-solute-binding-protein	gnl\|CDD\|270452	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold. This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.33059e-50
NC_014833.1\|WP_013496980.1\|241490_242030_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|131898	TIGR02851, stage_V_sporulation_protein_T, stage V sporulation protein T. Members of this protein family are the stage V sporulation protein T (SpoVT), a protein of the sporulation/germination program in Bacillus subtilis and related species. The amino-terminal 50 amino acids are nearly perfectly conserved across all endospore-forming bacteria. SpoVT is a DNA-binding transcriptional regulator related to AbrB (See pfam04014). [Regulatory functions, DNA interactions, Cellular processes, Sporulation and germination].	3.84527e-60
NC_014833.1\|WP_013496991.1\|252081_252333_+\|30S-ribosomal-protein-S20	gnl\|CDD\|376586	pfam01649, Ribosomal_S20p, Ribosomal protein S20. Bacterial ribosomal protein S20 interacts with 16S rRNA.	8.3458e-20
NC_014833.1\|WP_013496990.1\|250989_251859_-\|GPR-endopeptidase	gnl\|CDD\|237076	PRK12362, PRK12362, germination protease; Provisional.	5.52275e-81
NC_014833.1\|WP_013496981.1\|242076_242748_-\|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO	gnl\|CDD\|376698	pfam01980, UPF0066, Uncharacterized protein family UPF0066.	1.37543e-72
NC_014833.1\|WP_013496986.1\|247103_247595_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	6.177e-49
NC_014833.1\|WP_013496987.1\|247699_248821_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	1.67508e-155
NC_014833.1\|WP_013496985.1\|245306_246164_-\|NPXTG-anchored-protein	gnl\|CDD\|368289	pfam05110, AF-4, AF-4 proto-oncoprotein. This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X E mental retardation syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental retardation. The family also contains a Drosophila AF4 protein homolog Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila.	7.74103e-07
NC_014833.1\|WP_013496984.1\|244675_245191_-\|hypothetical-protein	gnl\|CDD\|227816	COG5529, COG5529, Pyocin large subunit [General function prediction only].	1.07168e-13
NC_014833.1\|WP_013496993.1\|253007_254789_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.65352e-167
NC_014833.1\|WP_013496992.1\|252555_253011_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	3.35959e-14
NC_014833.1\|WP_013496989.1\|250483_250933_+\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|107228	cd06471, ACD_LpsHSP_like, Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.	3.86856e-39
NC_014833.1\|WP_013496976.1\|236103_237063_-\|2-dehydropantoate-2-reductase	gnl\|CDD\|224805	COG1893, ApbA, Ketopantoate reductase [Coenzyme metabolism].	7.02164e-19
NC_014833.1\|WP_154662739.1\|248867_249923_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.56814e-50
NC_014833.1\|WP_013496983.1\|243307_244327_-\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|181535	PRK08673, PRK08673, 3-deoxy-7-phosphoheptulonate synthase; Reviewed.	0
NC_014833.1\|WP_013496995.1\|256867_257758_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	9.53108e-117

>NC_014833.1|WP_013496985.1|245306_246164_-|NPXTG-anchored-protein
MNKKLFALLTSAAMMAAVAPSVFAENNENNENNNNPAGATATLEFIPSAEKVAAGKEVTFDVAVSADVKLCTQQFAFTAENGEIVNFVFNEDNLKSTTAGLAFDYWGYKGKMTDAEKEQFVDNEEYQVMAYDQTFEDADGIVPNKLVIGTLTVKAADDAEDGTAINISTSTAKITAGGIANYDVDGYADWTTVPASVTVSADASESESESESESESSSESTSTSESSSESTSTSESSSSKATTNTSSKSNTNGTTSNTNTGAATTAAVALAASAAALVVISKKRK
>NC_014833.1|WP_013496984.1|244675_245191_-|hypothetical-protein
MKLKIFSLLTIIAVLFTLTGCSGQKNKSSDSLYDLIIEDSSSASTDNTSADPITAEDSSSEISSEPQSDIPADSEDPEDDEYTEYWFRTKKLRDQHYEKHGIEMGFASADDYRKAASDVVNDPSALHKTEKEDGDDAYYLEETNEFVIVSKDGYLRTYFKPDKGKAYFDRQ
>NC_014833.1|WP_013496983.1|243307_244327_-|3-deoxy-7-phosphoheptulonate-synthase
MVIVLKDSANKKQIEELMEWLTRFDVKSNLVEGVHSKIIGLIGDTTAVDIESVQAREIVDTVKRVQEPYKNANRRFHPLDTVIDVRGRKLGGDRLQVIAGPCSVETEEQTIKTAIAVKEAGATMLRGGAFKPRTSPYAFQGLGKEGIDILKKARAETGLPIVTEIMDVSDIDLFDDVDIIQVGARNSQNFTLLKALGRLNKPILLKRGLSGTLQELLMSAEYIMSEGNSQVILCERGIRTYETATRNTLDLASVPLLKQKTHLPVTVDPSHATGIASLVEPCSLGAVAMGCHALEIEVHIDPEHAWSDGAQSLTPEKFKAVMNKIRAMAEFCGRPVDAD
>NC_014833.1|WP_013496982.1|242823_243183_-|hypothetical-protein
MYIDNNYFEEKQTTIDSIEHYFTRYPIDKANIARMYSEEVLGVADTEQLIIAEIIFYHAMWKKAGGLPTYAIDRIKSLTNKIIQSNQSFNYLNGDEYNDFIKMVKELNESEIDLLGDNS
>NC_014833.1|WP_013496981.1|242076_242748_-|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO
MEIIARIHTDLPTKFGLPRQSGLVEELEGLVVFEPKYREPEALRGIEGFSHLWLIWEFSEAKRDSWSPTVRPPRLGGNKRMGVFATRSPFRPNPIGLSCVKLLGVEKTADQGLALRVGGADLMDGTPILDIKPYLPLADCRPEATGGFAAEKAGYSVKVDFPAELLEKVPESKRTALKALLAQDPRPAYQNDPERVYGFGYAGLDVRFRVSGDRLEVIEVEET
>NC_014833.1|WP_013496980.1|241490_242030_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKATGIVRRIDDLGRVVIPKEIRRTMRIREGDPLEIYTNPDGEVIFKKYSPINELSDGALQAAEVISKLGGAPAVIFDKDHVVAVSGVPKKEYSQRRLTQALENMMENRCSYEYRSGSAEFHPVEGIDTHALAVAPIISGGDITGAVAFLGGDDDRHVTDDQAMLCKAAAMFLGKQIEQ
>NC_014833.1|WP_013496979.1|239108_240401_-|extracellular-solute-binding-protein
MKKRKILATLVSAAMLATTLASCGDASGSKKKKNADGSQEITWMFWDDLNATEDLISLGYKETIERFNNDYKGKYHVTPITTNLEEYYNNLNAKVAAKETPDVFIVSPGPQLTDYVKPGVAAPLDDYLAKDGWKDTFTSDSVFSQQTYDGKIYAVPLNTAAACCFYNTEMFEKAGISDTPKTWEEMIAACEKLQGAGYTPISISANTAWCLSMVAGYLCEAEGVDLAKLADGSASWEDGKLENACNKLLDLSKYFQKTAGGDTNDVATAGFYNEEAAILIQGSWAIGQINGQNPDFESKCGVFQFPGVDRVIAKSDSLCMSSTTDCPEGAAALIKYFTDEKSQKYTAEKGGKIPVTKVEYDTSAAPKQLAFVMDVFSNATGTFGFYNESMPTTETGAHFDDTMVAVFQGSITPADAAKDMEEYYAANCRK
>NC_014833.1|WP_013496978.1|238131_239016_-|sugar-ABC-transporter-permease
MDKMLRSKKAIVIFMLPAFLLFTLVLFIPIIQSVYYSFCEYKVLQAPKFIGLDNYKAILSDKTFAIAFKNSMFFLIFSCVSQLILGLFYAALLTNIEKGRNLFKNIIYLPCVLSSAALGLLWMFIFSPKLGINLLLEKMGIEGPMWLSDIRGTIILPMWIIAFVALWQYVGQSMMLYMAQISGISKSLMEASYIDGCTKAMTFRYVTLPLIKPMVATAMSLNAIGSLKFFDLIFNMTEGGPNHKTEVLATHLYQQGFKFSKYGYASAIGVVLLILCLAVTLFINKVVKTEQYEM
>NC_014833.1|WP_013496977.1|237223_238117_-|carbohydrate-ABC-transporter-permease
MSSSKIGAAAPDPSSKQKITPIQIVIYAFLVIISLTYLLPLLWVFNVSFKTNKEIFTAPFALPQNITFDNYSFAWTAGNLGTATLNSFIVCVISLLLSMLIGSMAAFGISRLHWKGSKLAMTYFLTGMMIPIHCVLIPLFTRFANLNLGFTTLHLSNTLTSLVLPYLTFSLPITIFIMEGFFTSMPNELIECACMEGANIFQIFFKICLPLGRTGLFVTGLMTFVGNWNELLLAMVFISDETKKTLPVSLSKFVGPYNTNYSQMFAAIMIAVIPTIIVYCAFSNKIVDGLTAGAVKG
>NC_014833.1|WP_013496976.1|236103_237063_-|2-dehydropantoate-2-reductase
MRIAVLGIGVIGTTYAYAFQKAGHDTYHILREGKKDIPAKIGIHVLDGRYNAKGEEKNDVYKVMVAEDNSEYDFIIVSVASGKLDCAMDTIMKRNIKGTIVLFCNFWDERKDIERIVGDYEYITAFPTAGGHMSKDHELNCVLFDHVMLEGEAKANISNYAEILNLLRSADLKWEIPYDMFEWIWIHMAINAGVTSTAGRAGVLDDPNKLAMELMADSKALKLAVKTIRETLQIVKARGVDLKLYKNELLPYKIPAGLAGIAMKKMFSSNELTSRIMTLHNDISDILYGCKCVYDEGKKRELSLPLYYKNMEKILEQIG
>NC_014833.1|WP_013496986.1|247103_247595_+|large-conductance-mechanosensitive-channel-protein-MscL
MFKKFMTEFKAFALKGNVMDMAIGVIIGGAFSAIVTALTSCFINPLIAVITGGVKYDEEGNPQIVGGSFKIRGVSFDYGAFISAILNFLIIALVLFLLLKAINGAVSKAAALAKKKEEEEEAVAEPSAEEKLLTEIRDLLTAGATPEALAKIEAAKADNEAAK
>NC_014833.1|WP_013496987.1|247699_248821_+|alanine-racemase
MNFLRRCWAEIDLSAVDYNVCEYKKLLPQDTELMCVVKASCYGHSDELIVPRLQQVHGVRYFAVSNILEGIRLREIGINGDILILGYTPPECAAELVKYDIIQACTELCYAQELSANANGTVRLHGAVDTGMTRIGVHGTAEEQADELAKVSALPNISLEGIFTHFSSADGIDDADEKYTQMQSERFFRVRDLLKEKGIRLKHAHIKNSAGGAYGYGDESTLARLGIILYGLYPDPAKSLPFVPKPVMTLKAVVSQVKWIDEGTAVSYGRTFVSDRRMKLATVTAGYADGYPRALSNKGEVIIRGKKCRICGRVCMDQFMCDVTDIPDAAPGDEVILMNAEINADVIAALTGTIGYEITCDITSRVPRVPVNS
>NC_014833.1|WP_154662739.1|248867_249923_-|GGDEF-domain-containing-protein
MRFDDLNERTVYSIGGISLLVSHIAYLCIFSILGVKPMIYYNIFSVTFYFSMLVLLYKRPYRKRLVLISLVEVMVHSCLGCFSMGWDMGFGTMLLFLIPIPFYLPLRRMITPYLFSLVPFALYVAIAAYIRSGGGSGNIYTFNDRVINNIVYFMNISFAALILLYVSSIYMFSRELMQFKLVTKNESLIKLATIDPLTQLFNRRAMNEYLKLIQHNSIRSDKGYVVCIGDLDDLKKINDKHGHFTGDEVLRQTADVIARTVPAEGYAARWGGEEFLFIVPNADVSSGTELADKIREDIYKKSFRSDNGNFRVTMTIGVCRGEPGDDIEKIISHADKLMHQGKNSGKNKTVK
>NC_014833.1|WP_013496989.1|250483_250933_+|Hsp20/alpha-crystallin-family-protein
MLLPSIFGNDMFDDMMGFPRFDDFGDIDRKLYGKHADRVMKTDVSEHDDHFEVDIDLPGFKKDEIEIELSSGYLSIRASKGLDKDETTPKGKLIRQERYAGAMQRSYYVGKDITEEDIKAKFDNGVLSLQIPKKEPQKALPETKRIAIE
>NC_014833.1|WP_013496990.1|250989_251859_-|GPR-endopeptidase
MKDPRTDLAVEAARKLSLSRDLEGVSRRIDILSDSQLEIADITIESSSAALELCRPKGRYITLKALDGTFDDFCTCRDARIRTIAETLRRLADGCERILVAGLGNRQLTADALGPLTVDKIFATRHIKHLAHETETDELTEVSAIETGVLGQTGIESTEHIKALCEAVQPDLVIAVDALACWDLEHLGRTIQICDTGISPGSGVENSRKELSRATLGVTCVAIGVPMVVDLTSAAEMIFGAAAPEGCDRMTVTPGSIDKLAASAAAYISEGINLAFQKSLTAEELRSLI
>NC_014833.1|WP_013496991.1|252081_252333_+|30S-ribosomal-protein-S20
MPNIKSAKKRVKVIEKKTLRNKAIKSDLKTALKKADAAVANNAADKEQVVRTAIKKVDMACTKGILHKNNAARKKSQLAKKLG
>NC_014833.1|WP_013496992.1|252555_253011_+|winged-helix-turn-helix-transcriptional-regulator
MRKEIQKEVIIASKYVHQKIGCIINSELAHNDITAAQSHVLMFIMCHEPPVYPSDIQREMHISGATVSGLVKKLRAKGYLTLEGCDTDERRRGLIATEKAAMHKAEIENCMSSIEDKAFKGFEEDELETLNKLLSRMAENLKDAEKEGQDK
>NC_014833.1|WP_013496993.1|253007_254789_+|ABC-transporter-ATP-binding-protein
MKKILAQIKQYKKDTILTPIYAMLEVVMEVLLPYIMAMIIDKGIEKNDMKAVWLYGGLMAGAAMVSLFSGIMSGVHGARASTGFACNLREEIYRKIQTFSFGNIDKFSTAGLVTRMTTDVTNIQNAFQMCIRIAVRAPFMLISSMVMSFVVSPRMSGMFLVALLILAVALGLVVRFAMKTFSAAFQKYDELNSSVQENVSAIRVVKAYVREDYEKRKFRKASGNLYNMFVKAESIVALNNPVMMFVSYTAIIAISWLGAHMIVGGTLTTGELTSLFSYIFSAFISLMMLSFIFVMISMSTASIKRISEVLDEEPDLSDKADTIKEMKDGSIDFEHVDFAYFKGENKDVLHDIDLHIKSGETIGIIGPTGSGKTSLVNLISRLYDVTSGSVKVGGVDVRDYDMEFLRNNVSVVLQKNVLFSGTIIDNLRWGNEKATEEECIEACKSACADEFIERMPDKYNSHIERGGANVSGGQKQRLCIARALMKSPKVLILDDSTSAVDTATDAKIKQAFAERIPGTTKIIIAQRISSVEKADRILVIEEGRITGIGTHEELLKTSETYADIYNSQAGGGGDFDRPENADGKAVSVRKEGV
>NC_014833.1|WP_013496994.1|254789_256712_+|ABC-transporter-ATP-binding-protein
MPRPDRTAPRPQMSKDTFKVLGRVLKFMFKDYKMHFGIVVVCIIIQAVTTLVGMVFIQSLVDDYVVPMLEEKKELGDAFVADYKPLAMALVRLAVIYVLGLTSAYAYNRIMVNVGQGTLRNFRNALFDNMESLPIKYFDTHAHGDIMSVYTNDVDTLRQFIAQSIPQLINSTVTLVVTLISMFTRNIPLSLLSIFMAAVMMFVTAKISGNSGKYFAAQQKDLGEVNGFIEEMLDGQKVVKVFCHEENAQADFRELNDKLRDSANNANKFANILMPINGNIGNISYVLCAVFGAILLINNVGSITLGRLVAFLTLNRNFTMPITQISQQMTFVIMASAGAGRVMDLLDQTPETDEGYVEFVNAKFDNDGELKECAERTGTWAWKHPHKEDGTVTYTQMKGEIVFDGVDFGYNDDKIVLHDVQLFAKPGQKIAFVGSTGAGKTTITNLINRFYDIQDGKIRYDGINITKIKKPALRKTLGIVLQDTHLFTGTVMDNIRYGNLDATDEECIAAAKLANASGFIEKLEHGYDTVLKGDGGNLSQGQRQLLAIARAAVGDPPVLILDEATSSIDTRTEKLVQAGMDALMSGRTTFVIAHRLSTVKNSDCIMVLEQGRIIERGTHDELLEKKGKYFQLYTGSFAEN
>NC_014833.1|WP_013496995.1|256867_257758_-|homoserine-kinase
MINIKIPATSANLGAGFDALGLALNYYNYVEMEESDIIDIASSDGIDVPCDEKNLIYVSAKDLYAVCGKKLTGLKLRQTNNIPMARGLGSSSACIIAGLVGANRMLGDPLTKDDLVDLAAQIEGHPDNTAPALLGGIVTAVFDGRKVHWVKQEVYTKLKFVAMIPDFELKTEEARACLPKQVSHKDAVYNLSRAALFSASLLTGKFENLRTAVHDKLHQPYRMELIPGCREVFDIAYTHGAYASYISGAGPTVMSIVDVDNKFFAGKMRFSLDNAGLGGWQVKELAIDNEGTVFNP

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Crispr_ID: NC_014833_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_3

535125-535256

Orphan

Consensus_repeat	Method
AAGTTCGGGTAGTATGTTTCTCGGTGCCCATTGTAAGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014833_3

>merge|NC_014833|3|535125-535256|CRISPRCasFinder
AAGTTCGGGTAGTATGTTTCTCGGTGCCCATTGTAAGCTATAAAGAAGACCCGGTGACCCTCGCGCGGGTACGCAGTACGTCACGCCCATGGCAAGTTCGGGTAGTATGTTTCTCGGTGCCCATTTTAAGCT

>NC_014833|3|3|535125-535256|CRISPRCasFinder
AAGTTCGGGTAGTATGTTTCTCGGTGCCCATTGTAAGCT	ATAAAGAAGACCCGGTGACCCTCGCGCGGGTACGCAGTACGTCACGCCCATGGC
AAGTTCGGGTAGTATGTTTCTCGGTGCCCATTTTAAGCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_013497220.1\|526525_527668_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NC_014833.1\|WP_013497236.1\|555293_555770_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367067
NC_014833.1\|WP_013497233.1\|553036_553534_+\|CarD-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376818
NC_014833.1\|WP_013497227.1\|537987_540147_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380491
NC_014833.1\|WP_013497225.1\|533998_535024_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_014833.1\|WP_013497216.1\|523313_524636_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234586
NC_014833.1\|WP_013497221.1\|527831_528695_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497228.1\|540545_541577_+\|sensor-domain-containing-diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NC_014833.1\|WP_013497238.1\|556884_558003_+\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NC_014833.1\|WP_013497235.1\|554406_555162_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|380361
NC_014833.1\|WP_013497234.1\|553762_554392_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NC_014833.1\|WP_028504336.1\|544075_546139_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380491
NC_014833.1\|WP_013497224.1\|532175_533948_+\|dynamin-family-protein	unknown	unknown	gnl\|CDD\|206739
NC_014833.1\|WP_013497219.1\|525596_526337_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|211327
NC_014833.1\|WP_013497237.1\|556070_556649_+\|sporulation-initiation-factor-Spo0A-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|378047
NC_014833.1\|WP_013497218.1\|524964_525447_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497223.1\|531198_532179_+\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320684
NC_014833.1\|WP_013497232.1\|549572_552635_-\|RICIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|238859
NC_014833.1\|WP_013497215.1\|522594_523191_+\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
NC_014833.1\|WP_013497217.1\|524639_524960_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_013497220.1\|526525_527668_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NC_014833.1\|WP_013497236.1\|555293_555770_-\|hypothetical-protein	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0.00148506
NC_014833.1\|WP_013497233.1\|553036_553534_+\|CarD-family-transcriptional-regulator	gnl\|CDD\|376818	pfam02559, CarD_CdnL_TRCF, CarD-like/TRCF domain. CarD is a Myxococcus xanthus protein required for the activation of light- and starvation-inducible genes. This family includes the presumed N-terminal domain, CdnL. CarD interacts with the zinc-binding protein CarG to form a complex that regulates multiple processes in Myxococcus xanthus. This family also includes a domain to the N-terminal side of the DEAD helicase of TRCF (transcription-repair-coupling factor) proteins. TRCF displaces RNA polymerase stalled at a lesion, binds to the damage recognition protein UvrA, and increases the template strand repair rate during transcription. This domain is involved in binding to the stalled RNA polymerase. The family includes members otherwise referred to as CdnL, for CarD N-terminal like, whichdiffer functionally from CarD. The TRCF domain mentioned above is the RNA polymerase-interacting domain or RID.	2.80881e-16
NC_014833.1\|WP_013497227.1\|537987_540147_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|380491	cd06267, PBP1_LacI_sugar_binding-like, ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. Ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the domain sugar binding changes the DNA binding activity of the repressor domain.	1.81099e-40
NC_014833.1\|WP_028504336.1\|544075_546139_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380491	cd06267, PBP1_LacI_sugar_binding-like, ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. Ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the domain sugar binding changes the DNA binding activity of the repressor domain.	2.5565e-41
NC_014833.1\|WP_013497216.1\|523313_524636_+\|histidine--tRNA-ligase	gnl\|CDD\|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	0
NC_014833.1\|WP_013497238.1\|556884_558003_+\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	1.11471e-09
NC_014833.1\|WP_013497228.1\|540545_541577_+\|sensor-domain-containing-diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	6.97312e-35
NC_014833.1\|WP_013497235.1\|554406_555162_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|380361	cd02233, cupin_HNL-like, Granulicella tundricola hydroxynitrile lyase (GtHNL) and related proteins, cupin domain. This family includes archaeal, eukaryotic, and bacterial proteins homologous to hydroxynitrile lyase from Granulicella tundricola (GtHNL), a novel class of HNLs that does not show any sequence or structural similarity to any other HNL and does not contain conserved motifs typical of HNLs. HNLs comprise a diverse group of enzymes that vary in terms of their substrate specificity, enantioselectivity and the need for a co-factor. In plants, they catalyze the reversible cleavage of cyanohydrins, yielding HCN and aldehydes or ketones. Also included in this family is TM1010 from Thermotoga maritima, a protein of unknown function. Some but not all members of this family have N- or C-terminal carboxymuconolactone decarboxylase domains in addition to the cupin domain. Members of this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.50443e-49
NC_014833.1\|WP_013497234.1\|553762_554392_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.98674e-42
NC_014833.1\|WP_013497224.1\|532175_533948_+\|dynamin-family-protein	gnl\|CDD\|206739	cd09912, DLP_2, Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins. The dynamin family of large mechanochemical GTPases includes the classical dynamins and dynamin-like proteins (DLPs) that are found throughout the Eukarya. This family also includes bacterial DLPs. These proteins catalyze membrane fission during clathrin-mediated endocytosis. Dynamin consists of five domains; an N-terminal G domain that binds and hydrolyzes GTP, a middle domain (MD) involved in self-assembly and oligomerization, a pleckstrin homology (PH) domain responsible for interactions with the plasma membrane, GED, which is also involved in self-assembly, and a proline arginine rich domain (PRD) that interacts with SH3 domains on accessory proteins. To date, three vertebrate dynamin genes have been identified; dynamin 1, which is brain specific, mediates uptake of synaptic vesicles in presynaptic terminals; dynamin-2 is expressed ubiquitously and similarly participates in membrane fission; mutations in the MD, PH and GED domains of dynamin 2 have been linked to human diseases such as Charcot-Marie-Tooth peripheral neuropathy and rare forms of centronuclear myopathy. Dynamin 3 participates in megakaryocyte progenitor amplification, and is also involved in cytoplasmic enlargement and the formation of the demarcation membrane system. This family also includes mitofusins (MFN1 and MFN2 in mammals) that are involved in mitochondrial fusion. Dynamin oligomerizes into helical structures around the neck of budding vesicles in a GTP hydrolysis-dependent manner.	4.16915e-23
NC_014833.1\|WP_013497219.1\|525596_526337_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|211327	cd02553, PseudoU_synth_RsuA, Pseudouridine synthase, Escherichia coli RsuA like. This group is comprised of eukaryotic and bacterial proteins similar to Escherichia coli RsuA. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RsuA makes psi516 in 16S RNA. Psi at this position is not generally conserved in other organisms.	7.78967e-73
NC_014833.1\|WP_013497237.1\|556070_556649_+\|sporulation-initiation-factor-Spo0A-C-terminal-domain-containing-protein	gnl\|CDD\|378047	pfam08769, Spo0A_C, Sporulation initiation factor Spo0A C terminal. The response regulator Spo0A is comprised of a phophoacceptor domain and a transcription activation domain. This domain corresponds to the transcription activation domain and forms an alpha helical structure comprising of 6 alpha helices. The structure contains a helix-turn-helix and binds DNA.	5.35228e-29
NC_014833.1\|WP_013497223.1\|531198_532179_+\|M48-family-metalloprotease	gnl\|CDD\|320684	cd07325, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48 family Ste24p-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi. Some members also contain ankyrin domains which occur in very diverse families of proteins and mediate protein-protein interactions.	8.3818e-16
NC_014833.1\|WP_013497232.1\|549572_552635_-\|RICIN-domain-containing-protein	gnl\|CDD\|238859	cd01821, Rhamnogalacturan_acetylesterase_like, Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are highly branched regions in pectic polysaccharides, consisting of repeating -(1,2)-L-Rha-(1,4)-D-GalUA disaccharide units, with many rhamnose residues substituted by neutral oligosaccharides such as arabinans, galactans and arabinogalactans. Extracellular enzymes participating in the degradation of plant cell wall polymers, such as Rhamnogalacturonan acetylesterase, would typically be found in saprophytic and plant pathogenic fungi and bacteria.	6.34694e-56
NC_014833.1\|WP_013497215.1\|522594_523191_+\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	5.45852e-36
NC_014833.1\|WP_013497225.1\|533998_535024_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.07548e-13

>NC_014833.1|WP_013497225.1|533998_535024_-|CPBP-family-intramembrane-metalloprotease
MFNRTAYVQHNIENTDMTALKNDCLKLGAMLITYRLLTSYFVNMIFIILSCRFLSGKMLSYTSAAELLQSDYKDVIQSTTYAMVFNSSVTITSLIITLLFGCIVLGFSFNGYLKPSADGAKKGLHYFPACFVANVFLSVAINAFVHIMDSAGVTIPEADFSIKTPSTAAILFEFLYLCIIAPFIEETVYRGMILGTLTKYGEFTAILLSSLCFGLMHGNIPQAVSAFGTGLMYACVAVGSGSILPSLIIHALNNTVVSIYTIGNAMKIPHIDTINSTAQIAVAMIGFYVLMTRASYFGTYDGQSSVEKKAVTKAVFTRPAIIIYLLVLISRIIIDIITSNS
>NC_014833.1|WP_013497224.1|532175_533948_+|dynamin-family-protein
MKDNENVMAADENISTVREQLSEIIEDDKIAEILGRECVEQLKEFRALVDKRREEPFTLVILGDFKRGKSTIINALLGKKIAPINVTPETYTINEISFGHTQTVEAILENGQRVPLVLEDITRENLEKRMKLFPAKISCVQIKDNAPILKNIRIVDTPGLSDLESLDKQVQDYIVNADAIMYAASCLLPFSESEQVFLATHVSPQRFGMLYVLVNMIDALNTMADVNKIMRRFRGISERIVPNAFVYGISGGDELKRKLGEERPADKGTREFYETQFFQFELSLNRDIIMQKDVIRSKRVLTMLDRMHAEISSRLRMISDMAEMDKQLLEDKAKEFEQQCDELAAELEKRKPVLHLSILEMQQEAETWMYEFFAKLRTSILECRAKDDMGEDIYSPEDIEKYFYSFLMEKVGEAYRTCIECHRDAITELTDKMSREMASALGITNVAEVSKAPSVDRLMMSANKNVTRSVMGVKLFGTSENFSPAAMSTFSLIMKKKKQTDIIDIALENYDEIRINIVKDIKTVYQDLEVKAISRLESLYKYQVELSRNAIDQAKEMVDNEDKSELLETLADALKRLEAPKKILDANLPA
>NC_014833.1|WP_013497223.1|531198_532179_+|M48-family-metalloprotease
MSDINAKVNPLLQIDTGFRSYLKAYTRSYQSHMVDGSLDYAFESDFAVRQKIMSLGGSAKLFKAVNTQDISAEAKHLFVKCDQVGPLKYPEIYDKVKKCAERLELIVPIVFIREDMNRPLAYSITSDLIEPCIVLTKQLVELCSDDELMLLIGSECGRVQNNHCTFNMAYTYLKVNNEVFRPVERFYTQTIGSQLYSALVQWVRYADVTANRAGIICLDKPGQYLKIMCGLYRKGYVDFYGRSGAGIKYDELSWLSEQIHGSTSRNLSISKDLTDIERSLLASNEFLYCKTLYSWREDVVDMEGHAESGQICDVRTSVIVGNGGQL
>NC_014833.1|WP_013497221.1|527831_528695_+|hypothetical-protein
MRKYKLLIVAFVLVVVGMLCGCSYNESIDIECDGLEEDERVFVLVKPTDDDELRTPDDADITGSEIYTAGKDGFVLAEQLREPISVKISDEQPQLNCSLIFKNSESRRNFCEKHKVIRLAVCDDRWRIKKISDDIDVFFPEEYEVLDAGRYYVGTGAFENTDIVSAIDTSRVRASGAVLCFAAFFLLWPINAVQFIVMLVMTSKKRQSKPRNVFLWFGVLSVPNLFFSKLYLSAVDVFDLILHNSRSLPDALSGLLLIDFPWLAELLLLLVWYIFLRQKDDVMYKGC
>NC_014833.1|WP_013497220.1|526525_527668_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MASVSLREIYKKYAGGVIAVSDFNIEIKDKEFIILVGPSGCGKSTTLRMIAGLEEISEGELYIGDRLVNDVAPKDRDIAMVFQNYALYPHMTVFENMAFGLKLRKVPKDEIARKVEEAGRILDISHLLDRKPKALSGGQRQRVALGRAIVREPQVFLLDEPLSNLDAKLRAQMRTEISKLHKKLGTTFIYVTHDQTEAMTMGDRIVVMKDGYIQQIDTPTNLYNNPVNQFVAGFIGSPQMNFIDAKLLKQNGKYVVEFGSEDTKTSKGVKYQVEVPESKADPEALEPLVDQEVVLGVRPECIHDEEMFISAAKTGIINATVEVTEMMGAETYLYLTCEGINLTARVSPRSTARPQDEIQVALDPNRIHIFDKETEKAVVN
>NC_014833.1|WP_013497219.1|525596_526337_+|rRNA-pseudouridine-synthase
MGEIMRLDKLVASQFADISRADVKKLCLKKKIMVNGKLMARSDAKVDTDDEIIIDGRKLTYKKHIYIMLNKPAGVVCSTKEGASTTVLDLVPDELRRDGLFPAGRLDKDTEGFVLITDDGELSHRVLSPKTHVPKTYFVRLEKPWEDSYKDIMAAGMTIDGLHEGDSEEKCQPAQFLASDENVCECTLIIHEGKFHQVKRMFEKLGNKVVYLKRVAIGEMPLDRGLELGECLEIMHKDVEKLLARK
>NC_014833.1|WP_013497218.1|524964_525447_+|hypothetical-protein
MAENYSITVQLNKKKLKKHLNCDLVEYKPSMNVLSMGRFMRNHKMESIYYGRVSGDNVQIFYHKAKKKDGGMTGFFGKMTEKDDVCELTGKFRKPLYAYISAVILILFCIACAIGTLAAGSWQGALVFLGIGAGGGFVMLYDNYKKYLKKYLDGLADKKR
>NC_014833.1|WP_013497217.1|524639_524960_+|hypothetical-protein
MAGNRCEQCENIMVREIISPQEYLFCANSLVGLLIAGDVEMTFSNCPLGRIVDDDMKFTKNRYFHQFRCTKCGTIYGMLFNTKTGGEIRINDKVFNPADYPDKKEE
>NC_014833.1|WP_013497216.1|523313_524636_+|histidine--tRNA-ligase
MAMIQRPKGTADMLPSQAYKWHTIEKLASETAEQYGFREIRVPAFEETGLFLRSVGETTDVVQKEMYTVTATGDSEFTLRPEGTAGVMRAMIENGLLNEAFPQKVFYLINCFRHENVQKGRLREFHQFGCEMVGSADAKADADVISMAKSFMDRIGLRDIELNINSIGCPTCRAKYQQALREYFGARREELCDTCKERLEKNPMRLLDCKSPICKEIGKNAPLIIDYLCEDCNDHFEKLKKYLGLMGIDFVVNPRIVRGLDYYTRTVFEFISKDIGAQGTVCGGGRYDGLIEELSGKAVPALGFAMGIERLILTMEAQNCDFMEAKTCDLYIASMGDDAADKAMELAMKLRDEGYFVEYDLMGRGIKPQMKYAGKIGAKFVLVIGSSELETGCAKLKNMASGEQADIKLDDSFIDDFSNALMAEMFKDIDGEMAALLGKE
>NC_014833.1|WP_013497215.1|522594_523191_+|YdcF-family-protein
MKLSEMLNDSPCDENIHKLLYDGLDYDGSSADLIMVLGSRKACDYRVPEAVRLYNEGKAPLILLSGGQVQDTSLGNMAEWESMKKAALALGISESDILAEKLSKNTAENFMYSDELLIGYLPLGSKIILVTTAYHMRRALCMAHKFMPGYDFIPCPVQKGSATKENWYKTDKGRQTALDEWRKLSYYIKDGIFEDTNI
>NC_014833.1|WP_013497227.1|537987_540147_-|substrate-binding-domain-containing-protein
MKKRKLFGVIAAAAADTEQREVIKGIIEKTREMDIDVAVISNIYNPMEWASMLKTENLIYDLVHSDEYDGIILISESVIYPDVQKKMLEELQNKSAPVITIGALPEGFSLPTFTCINTDDVNDFKDICDHLTDVHGFTDIHILTGYSELELSHKRVEGYRRSLEEHGIPYDENKVFYGNFWNNSGYDHAMRYISGELPYPQALICGNDYMAYGLLDCFLEHNIDITKKMAVTGYEYIRERYCHVPILTTYQRNRKALGIKAVEMLCKGADNITHDDFEPPKGNIISGDTCPCGAKTEDIRYDIRTARKKDIYDRLDLYSLLEHKLIECRSVDKFVETCREEKFRIKNADRLYMCLYENWYEGTGNSSNMVCYDLIDNTEPFMFNKYNISAVFGNEAASYYFCPLFFADRELGYIVLRFKGNDSFRHIFRCWLKTIANGLEFLRMKNDIRFYLQCQDISEERDTLTGMLNENGLKKAYRNTEKDGLSFVAIRIAPGICNCGVGHKEHIDAVLDAAEAVRQFSDGQICSRINEDTFVCLIRDMTDNTDLLAVQLSALLQHNTSYIKKYGLDSFVCTAVPCEDNDYLTTKEKCFARMTEMTDVYSARRTDPHYKKLNALRTMIYSTPQITFDQREIYSHFNGSDGYLRTIFRKCYGFTLHDDCTNARISAARYLITMSKLSNSEIAEKCGYNDPKYFMRQFSGITGYTVPRYRLLFSRSAEE
>NC_014833.1|WP_013497228.1|540545_541577_+|sensor-domain-containing-diguanylate-cyclase
MNNDNENLKNAMIIKNLTLFFGGFLLFTDVFFLAVGIVYDMPLIRYLIYVKLVINTTNIYLILKKHYLVSTVIIYVVIMAMMVVGIISMGTRPAFQLYALGMLICVSYNGYLHNRILKKELPFMLMMGIHVLLYTGMLLYARFREPLYTYPQSAVDILVIFNSVATFSIVILYAFLFHNVAIHSEEKLEKMALMDKLTGLYNRHYLLAFLDHTGPRNPEDRWIAMLDIDDFKKINDSYGHNCGDFILHEIAAMIRDVCKNCIVCRWGGEEFIILSNINECSTEVLETLRKNIENREFIFEGNTIHATVTIGECRYETGQSNDKYGYPWLTKSFMKANTAARTV
>NC_014833.1|WP_028504336.1|544075_546139_+|substrate-binding-domain-containing-protein
MISNIYNPEYDDEQLAAENDIYRLIESPDLCGIILVTEAFINPTHRRQISQLMNYRSDIPQIAVGSYFEGFELEHCIPLNTADSDDIADLTEHLITVHGFTEIDLLTGFESYSVSHLRIDGYRSALEKHGIPFDEDRVIFGDFWMPSGEKLAKAYISGERPMPQAVICANDYMAYGILDVFAEQGISVPGDITVVGYEFVRERHMHTPVLTTFQRSREALGRIAAEMLLNKVSSGEFGVLVPPRGKVICGDSCTCGIRPADLNAELSAARTKAFYEFLHLYNQLEQRLTEAHSMRDFCGKFVGSEYLLRNISGAELCLYRNWHNGAADDSMMNCYTLYNESLNGQSRNISRLELSALTERSGAPAVYYCSPLFFGDRPMGFVVTRYEIPETYDHIFRSWMKSVSNALEILRMKNDIKYLMECCNISEYQDTVTGLLNRKGFSHELHILIRKAVKRQPVFCLLLQTAIDRDNLSLKNKTKEIAIQQEISAALQVVAPSFICARLEPNIYAVAGLYTDEDMELLLRERVTALVLNNEKYIDLFGMDSFCISAVCTEYSSSTELMNIAEKELMVQADILRDSHLNTHYRQLISARNRLYSGREAPFTVEAICRQYLISAGHFRKIYKETFGIAYHQDIIRMRMMKMIWLLISTDLDISVIAERCGYDDYGYCLRLFRQFTGHTPNKYRKL
>NC_014833.1|WP_013497232.1|549572_552635_-|RICIN-domain-containing-protein
MRFKKLVSGLTSAALSLLMLSGIGVPNANGVLTAKAATANWKFDFGTGGTASGYTGVSASDEYASWRGYGFAQTGNVGNVSAGGNGAGSDAVEFKSDSGSNTFNVDLPKGLYEVKVTVGNAPRCCIKMEGMFQMMNLTGLNASETVKLPVTDGQLNIQAVTGISNGQRSISAVEITQINTTGVMPKTVWICGDSTVANYYNRSSTQAHGWGQYFGTYASQHGFEVRNMATSGQYAKGFYDGGQFTPIETYGKSGDIYIISIGINDTNYSNKDEYHSTVSTMTQKAKAKGMDVILVKQQGRHADYNRNPKLSGRWFGGELDSVASEENVRVVDLFNAWQDFGFSIGGYDAMTPYYASGDDLHQSLEGAKKLAELMSGLVFETKEPVQMDTSKMYRFKNVNSGLYLEVKNGEAAVGANVQQWSGAQVGDWNTWRLKHKGYNYYEIWSYLGGGSTYLLDVANGSSANGANIALNTNQNYGAQWFRFFENGDGSYTMVSRCSGDKGAIEVGSALTYEGANIQQWEVNGHNCQKWILEEVQPNDPEPEPEPEPEPEYTNTLTRYPGDANADGKVDMADAVTIKQYLNNSYRYPLCKQGMKNADVDGNGSINDNDVLYIQQYALGMRSFPAPVYENVSVSTDPWDGYYFAVDQTWDDAWAEETNSGFTKTSTDIGKSSNTGYINLNNAVGSSLTFKVTAPTSGKYMAYVRFSNGSSSSRDTKVFVNGNTSSYWIQTFASTGAWTTWDALGLVLPLNAGDNTIKFESAGSDGGPNFDYLTITLTDEPVAELYDPNAQEQYIDNTKPALYLAGDSTCMYYNANKQSQQGGPIQGWGYELPKYFSSNVSIYNHAMAGRSSKKFYDEGRFATIVQNLKKGDFVAIQFAINDAGKSYADRYAPLCGNVDNPSSGSYEWYMTSFIKDTKAKGATPILMSCTLGLKAYKNGRFTGSYTEYADACKKLAAKYSVPYVDVNGAMVNYYNSIGYDNAAKLHIDTTHFNETGAPVIAQLIANAIKSANISGLSNYVK
>NC_014833.1|WP_013497233.1|553036_553534_+|CarD-family-transcriptional-regulator
MYKTGDVVMYGTSGICRVAAVEKRDLTGEEQEYYILRNIYSDKNIYYVPVNNEAALGRMHPVCTKSEVDELISHMNSEGLIWIDNDNKRKEEYSRIIKDADKHEIIRLIKTLYLRRRELSENGRRLRSSDENYLGIAEDMLFEEFAYALGIDRCEVVDYIEKHLA
>NC_014833.1|WP_013497234.1|553762_554392_+|flavodoxin-family-protein
MKVLILNGSPRVNGNTSIAVNELVKTFEKEGIATEVCHIGNKDIRGCIACGKCSAQGRCVFDDAVNEIAAKFEQADGLVVASPVYYASANATLIACLDRLFYSSHFDKTMKVGASVVVARRGGCSSTFDELNKYFTISGMPVASSTYWNSVHGREAGEAEFDAEGMLTMRSLARNMSFLMKSIALGKEKYGLPDGEPWQPTHFIRDDLK
>NC_014833.1|WP_013497235.1|554406_555162_+|carboxymuconolactone-decarboxylase-family-protein
MAEKIVQTAGRDQLGEFAPDFARFNDDILFGENWNNTDIDLKTRSIITVVALMSQGVTDNSIRYHIMNAKNHGVSQAEMAAVITHTAFYAGWPHAWAVFGIAKEVYADNAPALSEKDRFQKELFFPIGEPNPYGDFFVGQSYLAPVSTEQIPIYNVTFEPGCRNNWHIHHAKNGGGQMLICVGGHGWYQEYGREARPLAPGDIVNIPANVKHWHGAAKDSWFAHLAIEIQGEDSSTEWCEAVNDEDYLKLR
>NC_014833.1|WP_013497236.1|555293_555770_-|hypothetical-protein
MERTLRQRIKTIKEIKNQHGMSIPQIQDIVAEHGGYVSPRTMYDIFAEGSEEKNFHYQSIAPIYESLIEVYGDDYTTDDVAALKQMLKERNRQVDDLLIQLESKHDEFEKRLSIYEERKNAYERSISLLEKQLDQLDRLLFDRDRMLQQLLDAYIPNQ
>NC_014833.1|WP_013497237.1|556070_556649_+|sporulation-initiation-factor-Spo0A-C-terminal-domain-containing-protein
MNMVMIEEKEELLSVKLAERLKKDGFFVVAHGTVLEIMNYIFEVKGTGGQPRHNGLRYELPAEYGEDTLYSYIKMTVSTPLERKVEDMTVDTVLSLGISRALRGYSYLAASITMCVACPDKLYSLNKDVYPEIARKYNVDVSCIERSIRHAICKAYSEDPEPMKKLFRRPIRRPKCQELIAECADIIRRIFY
>NC_014833.1|WP_013497238.1|556884_558003_+|ISAs1-family-transposase
MNNGITEYFEDIELYEEYDGYFCSIPDIITIAILGSICGLRNIHQIHQWATNDRVSEFLKEKFGIDHVPCYYWILSLLKYVKPESLNRCFADWVYSFMPEKSKSMTISLDGKTVCSTLKMSKIESPLHIISAQVCELGLTLAQRSTDDKSNEIPAVQELLKEPKIKGNIVVADALNCQKETAEIIVKQKADYLLCVKDNHPNLKKDIEDYVQDSSLRDTMQTVSRTEKNRGRVETRTAYVTTDINWLEQKKEWKNLKCIGAIHTEFSTKKGTSSEWHYYLSSREMTAEQLLHHARMEWSVESMHWLLDVHFEEDWCRVENKDVQQCLNMFRKAAINLIKNFKNRNNSKAAISKLMFECLMEPQMISRVIFEN

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Crispr_ID: NC_014833_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_4

813193-813294

Orphan

Consensus_repeat	Method
ATGTTGTTCTTTATTTGTTCTTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014833_4

>merge|NC_014833|4|813193-813294|CRISPRCasFinder
ATGTTGTTCTTTATTTGTTCTTTATCAAATATGGCGAACATCGATTCTGCACCGCAGGAAAGGCACGCTGAGACAAAATCTTGTTCTTTATTTGTTCTTTAT

>NC_014833|4|4|813193-813294|CRISPRCasFinder
ATGTTGTTCTTTATTTGTTCTTTAT	CAAATATGGCGAACATCGATTCTGCACCGCAGGAAAGGCACGCTGAGACAAA
ATCTTGTTCTTTATTTGTTCTTTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_013497456.1\|824180_824429_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497451.1\|819008_819491_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|238032
NC_014833.1\|WP_028504317.1\|812472_813048_-\|type-IV-toxin-antitoxin-system-AbiEi-family-antitoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|379128
NC_014833.1\|WP_013497438.1\|806231_806618_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497453.1\|821197_822280_+\|SMI1/KNR4-family-protein	unknown	unknown	gnl\|CDD\|378155
NC_014833.1\|WP_013497454.1\|822891_823803_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_080557247.1\|818387_818552_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_014833.1\|WP_013497444.1\|810511_811417_+\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|378065
NC_014833.1\|WP_013497442.1\|809200_809683_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341260
NC_014833.1\|WP_013497443.1\|809907_810522_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497436.1\|804117_805749_+\|DNA-cytosine-methyltransferase	unknown	unknown	gnl\|CDD\|223348
NC_014833.1\|WP_013497452.1\|819526_820843_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292
NC_014833.1\|WP_013497445.1\|811631_812471_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|378065
NC_014833.1\|WP_154662833.1\|816703_817279_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224489
NC_014833.1\|WP_013497441.1\|807911_809105_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292
NC_014833.1\|WP_013497437.1\|805711_806131_+\|DNA-mismatch-endonuclease-Vsr	unknown	unknown	gnl\|CDD\|226250
NC_014833.1\|WP_013497450.1\|817312_818131_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293807
NC_014833.1\|WP_013497440.1\|807176_807401_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_014833.1\|WP_154662832.1\|823836_824118_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497447.1\|814000_815566_+\|AAA-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|379062

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_013497451.1\|819008_819491_+\|HD-domain-containing-protein	gnl\|CDD\|238032	cd00077, HDc, Metal dependent phosphohydrolases with conserved 'HD' motif.	2.65922e-05
NC_014833.1\|WP_028504317.1\|812472_813048_-\|type-IV-toxin-antitoxin-system-AbiEi-family-antitoxin-domain-containing-protein	gnl\|CDD\|379128	pfam13338, AbiEi_4, Transcriptional regulator, AbiEi antitoxin. AbiEi_4 is the cognate antitoxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	0.00682342
NC_014833.1\|WP_013497453.1\|821197_822280_+\|SMI1/KNR4-family-protein	gnl\|CDD\|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	0.000179409
NC_014833.1\|WP_080557247.1\|818387_818552_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	4.92368e-06
NC_014833.1\|WP_013497444.1\|810511_811417_+\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	3.3308e-20
NC_014833.1\|WP_013497442.1\|809200_809683_+\|hypothetical-protein	gnl\|CDD\|341260	cd05937, FATP_chFAT1_like, Uncharacterized subfamily of bifunctional fatty acid transporter/very-long-chain acyl-CoA synthetase in fungi. Fatty acid transport protein (FATP) transports long-chain or very-long-chain fatty acids across the plasma membrane. FATPs also have fatty acid CoA synthetase activity, thus playing dual roles as fatty acid transporters and its activation enzymes. FATPs are the key players in the trafficking of exogenous fatty acids into the cell and in intracellular fatty acid homeostasis. Members of this family are fungal FATPs, including FAT1 from Cochliobolus heterostrophus.	0.00171065
NC_014833.1\|WP_154662833.1\|816703_817279_+\|hypothetical-protein	gnl\|CDD\|224489	COG1573, COG1573, Uracil-DNA glycosylase [DNA replication, recombination, and repair].	1.89186e-06
NC_014833.1\|WP_013497436.1\|804117_805749_+\|DNA-cytosine-methyltransferase	gnl\|CDD\|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	4.79938e-33
NC_014833.1\|WP_013497445.1\|811631_812471_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	5.80458e-32
NC_014833.1\|WP_013497452.1\|819526_820843_+\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.51305e-79
NC_014833.1\|WP_013497441.1\|807911_809105_+\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.15954e-78
NC_014833.1\|WP_013497437.1\|805711_806131_+\|DNA-mismatch-endonuclease-Vsr	gnl\|CDD\|226250	COG3727, Vsr, DNA G:T-mismatch repair endonuclease [DNA replication, recombination, and repair].	6.60703e-58
NC_014833.1\|WP_013497450.1\|817312_818131_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.43016e-32
NC_014833.1\|WP_013497447.1\|814000_815566_+\|AAA-like-domain-containing-protein	gnl\|CDD\|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	2.7124e-05
NC_014833.1\|WP_013497440.1\|807176_807401_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.72545e-08

>NC_014833.1|WP_028504317.1|812472_813048_-|type-IV-toxin-antitoxin-system-AbiEi-family-antitoxin-domain-containing-protein
MTELIKEYGCITPEIAADNGISKYKFYKYVRENNMEQVEHGIYIFRDEWVDELYVLHKRCPNAVFSHNEALYFYGLTDREPLVHTLTMYSGYNSHRLTADGRCKVYTIKKELLDVGKVFVKDNCGNEIPMYDIDRTICDVIRSRSTIDIQEFIPALKAYARRNDNDLNKLWEYSKLFRIQTVVRKYMEVLL
>NC_014833.1|WP_013497445.1|811631_812471_-|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MQLTPEQVKCRIKKLAKVKNTDARVLMRIYMMERFLERAANSEYNDNFVIKGGMLVSAMTGVALRSTIDIDTSIRNQNLSAADPRDIIENITAVDLVDGVRFEIKDISDILDEIEYPGIRVILNAVIDRLITPMKIDISTGDAVTPRAIKYDYKLMFDDRSIKLWSYDLETILAEKLRTILARSVLNTRMRDFYDIYILLSLYENKIDGTVFREAFDAACQKRGTVNLIQNAPAIIANINEDNTLHKLWGAYQKKYPYAKKIQYDDIMDGVKSLFGKLA
>NC_014833.1|WP_013497444.1|810511_811417_+|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MLHNEKDIFEQLILRTSEYLGVKAEIVEKDYFVTLFLKKIADVMPDIVFKGGTSLSKCYHIIKRFSEDIDLNLQSEIKPPVGKRKQLKASIISIISDLEFELTNADAIKSRRDYNRYIIDYPSSLSAVYLKEQLIVETAIYQRAYPTKVMKADSLIYQYLHENGYDNYAEQYGLQPFELNVQTAERTLIDKLYALADYYLLNTTTEHSRHIYDIYKLSEIVTINDTLRSLAQSVADERRPHKMCLSVQNGTDVNAVLREIIDKKVYKDDYDTITVPLLFESVSYDMAVSALENILQSGIFD
>NC_014833.1|WP_013497443.1|809907_810522_+|hypothetical-protein
MLFDYLLETFGQNEPIFLSDISYEDYSDIWLKKELAKLCECGQIIRYERGIYYIPVKTPFGNSILNPNRIIERKYLSEKGNRIGFYTGITALQQAGLSTQMSNIPEIQTNNENSKLRRVKVGNQDIILRKARVKIDNDNIFVLQFLEMMNSTSAGYFDDERKAVIRNWIRKCNISQELVTKYAPFFPDKTMRNLIESGVIYYVA
>NC_014833.1|WP_013497442.1|809200_809683_+|hypothetical-protein
MEKKKEMSINNFALLLALIFFLVGAYPGFRSLNLKKKCTVEIKGIIVAERSGPKYPDRSHPKNKYLWGRGITDIYVETDGIFKYDKLSAGAGVGEIGDEVIIRYDPDDPDEYYFVGYYGLDRTNAAFAWGLSGIMIIWSLVDFIYYNIPLVFPKLLQKKQ
>NC_014833.1|WP_013497441.1|807911_809105_+|ATP-binding-protein
MIDRPEYLRFLNDWKDKQIIKVITGIRRCGKSTLFELFREQLGKQGVGDDQIISINFEEAENEELHDWHKMYSYITSRMLPDKTNYIFLDEIQCVADYQKAVDSLFVKKNTDVYITGSNAYFMSGELATLLSGRYVELKMLPLSFKEYSSAFDGLSKEELYRNYVYNSSFPYTTELHDRRNIRTYLDGLYNTIVLNDIVTRKKIQDPLMLKSVIKYLFDNIGSPCSSKKIADSMTSAGRKISNHTVENYLEGLTDSLLMYRVGRYDIKGKEYLKLLDKYYAADVGLRYYLLGTNNADNGHILENVVYLELIRRGYEVYIGKNGNTEVDFVAVDYDGNTEYYQVSWTVRDEKTLERELTPLQNINDHNTKILLTMDNDPPVSYNGIRQKYVLDWLLDK
>NC_014833.1|WP_013497440.1|807176_807401_+|helix-turn-helix-transcriptional-regulator
MPVIDVKATGNNIKNIIRSKGFKISDVQARCGFNTPQAIFKWMRGDAVPTIDNLIILADMFDTPIDKIIIVTRI
>NC_014833.1|WP_013497438.1|806231_806618_+|hypothetical-protein
MMQTLTKEQFISKISDIERVCLVSIHDGKVYLRADIEKGGDNGLRIEMMDFEMNTSYGFYEANSLCRSNYSGGISFIEYSSYVEAEHRAINDFLDLNPHSALLYCDDNELYELTDKYPADTDLYVAVN
>NC_014833.1|WP_013497437.1|805711_806131_+|DNA-mismatch-endonuclease-Vsr
MADNHTKEIRSYNMSRIRSVNSKPELLVRKYLFSKGFRYVLNDKRYPGKPDIVLPKYKTVIFVNGCFWHKHDCGRFVWPKSNIEYWRTKITRNVERDNANYIKLSEMGWNVIVLWECQLKKDTMTKTLDELSFQLKKSI
>NC_014833.1|WP_013497436.1|804117_805749_+|DNA-cytosine-methyltransferase
MEKYKVVDLFAGAGGLSLGFVQTKKYEIKVAFENNPNMQKTYRRNHPKVDVRGDVCAADYSEIKRKYGTIDVVIGGPPCQGFSNANRQKNTAVSLNNKLVKQYVRAVIELSPNAFIMENVSMLKSEVHRFYLEKGDEELIKEYNIKVKMTPLKLVDSQYCFDGILDVINDQSSIEKFIWPERLYQEINVIYKITSNLSKLKTTLDKHKNTLLKLINEYEKANSLTGYIAECSNKAFETIRSYYENRIDCSNIKQGIESAIMLQRMLFKSLEIINNKILVDEYDTENGISANIRSMAVLDYIKAILESPKYGYKLNSNVLCAADYGAPQKRMRFVIMGIKSSISSIPTFPMPKFEEDEYRTVRDAISDIEDVEPVVNITDDVGIVLENKDLEGLAKKLRDSKKLYNHIITATTETAMKRFKVIGQGQNFHSLSDDLKSNTYTNPNRTQNTIYTRLKYDEPSGTVVNVRKSMWIHPTKDRALSIREAARLQTFPDSFVFCGSKDQQYQQVGNAVPPIMAKAIAMKLNRILEKSYGRQSHKRNKKL
>NC_014833.1|WP_013497447.1|814000_815566_+|AAA-like-domain-containing-protein
MPKKFNITGNCIPDRHYMVDLTSRLEQIKAQVDDGQYLVINRGRQYGKTTMLRALAKFLSDEYYVLSLDFQMQMSSQKFESENIFSVTLAKIIIRAFRQLGIDRQFEKEINGIGSDIADMKENYGLVDLFISLNDICAASDKPIVLMIDEVDQASNNQVFLDFLAQLRGYYINRDVSPTFRSVILAGVHDIRNLKQKIRPDEAHKHNSPWNIASSFDVDMDFSPADISTMLSEYENDHHTGMDIDRMAQLIYDNTSGYPVLVSTICKHIDEQIHEWDEHGVTEAVKLLINSSSPLFDSLINKLEDNKQLRNMVYDILINGRTFIYGPDSEVTREAEMYGFVTRCDTHVAIANRIFETRLYNWFIYDTVADNDKKDWSADKNRFITNGRLNMKLVLEKFVTHFDELYGDSSEKFLEEDGRRFFLLYLRPIINGTGNYYVEALTRNDRRTDVIVDYKGEQFVIEMKIWRGEEYNARGEQQLTEYLDYYHIDTGYLLSFCFNKSKNVGVSELKIGKKTIIEALV
>NC_014833.1|WP_154662833.1|816703_817279_+|hypothetical-protein
MVGQDWGNYNDPDSKSLMESIRLYNDDHNNLYDYLKGNDNPTDMNLCKLFENIGIKIDRPNTDEFFTNFVLCYRSGNNGISGGFKQIWAKNCSTYFVRLVRIIEPQVIICLGRAVFSNVLKAAGIKMPHMKYNDIIESKVYDAAFGDHACKVYPVAHCGVLGTNNRNRDKEFSHILDVQKQDWKKMMSELK
>NC_014833.1|WP_013497450.1|817312_818131_+|MBL-fold-metallo-hydrolase
MFSKPIIELKYSNTNTYLIKGKKGSLLFDTGWAGTFPQLCRALGENKLKFQNISYLLISHFHPDHMGIAQEIANSGVTIVAADVQAEFIHSSDHIFAKEKDSDFVPIDDSSIRLVKVSESRSFLAELGISGEIIHTPGHSDDSISLWLEKERALFVGDLNPLYELDMHKDTQIEDSWSGLLKLDPKTVYYGHAMTAKLTGKGVQPKQQSDNADTYALVKKIMKLIDKGCDDVTIQQKTGADKVFIQDVARMYLTHQNVSVQGILDRIEIKGK
>NC_014833.1|WP_080557247.1|818387_818552_+|helix-turn-helix-domain-containing-protein
MFLICSIAALLHVSKQKLASIIKSGELKVIELGPRSRRIPKSSFEEYIKNKTTR
>NC_014833.1|WP_013497451.1|819008_819491_+|HD-domain-containing-protein
MERQYTQIDQVRALIDTIIKAIEDEETKRCAYVHLYGVGLMAAMIALKRGHSRRTAELAEIAGMLHDLLKYHDPTIADHAHEGAEFARRQVLDKLDCLTEEEKQLVYDGIYNHSDKHIKSTPFDEIIKDADVLQHSLRNPCEDYYYFDSRMQQLLDEIID
>NC_014833.1|WP_013497452.1|819526_820843_+|ATP-binding-protein
MIENKELRNRPQYIDKLIGFQDTEPVKVVTGIRRCGKSSLLKLMVRHLLDEGKSEEQIIQMNFESYDFKNMTADDIYSYVKERVVQGKRMYLFFDELQRVDKWEDAVNAFRVDMDCDIYITGSNAYLLSSEYSTYLSGRCVEIKMLPLSFAEFTDFYGFEVRKVKSALGGTRKLAYDKNGQQYDLREIFDAYMRFGGMPGIADTGLDQDKALALLDGIYSTVIIRDILEREKRRGQKSITDAALLRKIIMFLADNIGSSVSVSSIGNTLVNEGLLNDEKRKGKPSAHTVSAYVNALTESYFFYEIKRFDIKGKEYLRTLGKYYIVDIGLRNYLLGFRDRDTGHALENIVYFELMRRGYDVAIGKIDNAEVDFIATKADDKLYVQVTESMTSETVRNRELAPLMKIRDNYEKIILSLDTGLENSFEGIKSLNVLEWLLK
>NC_014833.1|WP_013497453.1|821197_822280_+|SMI1/KNR4-family-protein
MSKYNTNDPEAVEIRKKIEKLISLNPDIEIYDIISIEEVKRFEAENDIKLPNDYVWFITNVGNGGKWYGGEYQFYPLEKTYFSYEGLPDYKTGREKYSIDILSTGCSYSKGIILRGEHYGEISSDGDGLAFYHPISLHGFKEFYLKWLEEACLGYNNLFFDSRLYGTIEEHLEQYISNPDLELLWSIFYKVNKQCATKQFISDLYTVFVSETDNDNKVMLARILIKSGYEDTFSVLSTIFSPQNYETIVWELHSSICYFKKWLYAEGVMEDAPKYYDMLVEIMKYYETAKERKHFDHCLNMTIMNPKFNENDILGILTSDDEEIVKHLANSVFQNNILNRVGKYIDAAKIKYEKMNENKG
>NC_014833.1|WP_013497454.1|822891_823803_-|hypothetical-protein
MKNTEKNIAYFHLPGLFEFYDLYSVFLPLYREHREYFYDRFEIASVYGAPADCIWGGGRVGAGECKAEDVLALMKEYGISSRLTFSNSLLRPEHLTDRKCNALCELFAASKGVRNGVIIHSELLLEHIKNIYPELYFVSSTTKVQTDFDEFLSETKRSEFKYVVPDFRLNKQYDKLAALPQVLKDKVEFLCNECCSFYCKDRKACYENVSRKNLGESCEDHICKAPGAEEGYRFSKAMKNPAFISTDDIINTYLPLGFSNFKIEGRGLGSAVILEFLLYYLTKPEYRLTVREEIYLDSMLDLF
>NC_014833.1|WP_154662832.1|823836_824118_-|hypothetical-protein
MDINTLFSMPKDVTHGREYVFDHAFGGDVWNSGNGITDIYFPGADTVGMQSFQKVPYATVYFSVSRMEASYGPDYAYTIASLCVPAKVVFDLP
>NC_014833.1|WP_013497456.1|824180_824429_-|hypothetical-protein
MNLLCSCCKSRITNDDRNRHLIEGAGIHNIGYKLAWMECAKEELCLPPDKRKWIHTDQVPIIGERRILKVTVPFDDFAAARS

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Click the colored protein region to show detailed information

Crispr_ID: NC_014833_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_5

1313206-1317474

TypeI

Consensus_repeat	Method
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CRISPRCasFinder
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CRT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	PILER-CR

63 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NC_014833_5

>merge|NC_014833|5|1313206-1317474|CRISPRCasFinder,CRT,PILER-CR
GTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCGTCACAAGGTAGCAAGACTGCGTGTTGAGAAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTAGCATAGCCTTATCATTACAATTAAGTTTGCTAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGTCCTGCAAGTATCTGTGCGGTCTGTGCTGTCTGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGTGAGTTGTTGAGCCAAGGGTAGAGGTAATCCAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGCAGACCAACGTTCTCGCGCTGTGCCTGTGCCAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATCGACCTCTCACATAGCTATCTATGGTATCGCATAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCGATACACTGCTTGATAATCTTACCGTGTTATGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGCAGACCAACGTTCTCGCGCTGTGCCTGTGCCAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGCCATTCAAGGTCAAAGTATATCGGATATTCAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATATAGCGTGTGCCGTTCTGCTTTACCTTATCAACGGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGCAAGGGTGCGGATGATCTTCGTGGGTATCTGATGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGACTGCACAGCCCATAAGTATCTCGGGGCAGTGAACGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGCGGCTTTGGTGCGCACCTAGAAAAAGGTGAAGGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAACGCTGTGATGATCTGCAGGATAACGCGGAAGTCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAGCGGTAGAATATCGCGGTTGATAGCCTCGATCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTATCGTCCAGAAAAACATAGCATAAGCCTGTGGCAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCTCTGCCCTTAGGTTTGCAATAAACGTTTCCCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAAGATATCCCTGTATCTGATTTCCAAAGCTTACAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTATGCCCTCCCGCTTGGTGTGCTCTATCTTCCGCTTCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAGTTATATAATGCTTTGTGCCGTTCTTATCTTCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATCATAGCGTAACAATTGCCGCTATCAAGCCCGCTATGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAACCTTAGAGAACACGCCACCTTCGCCGAGGATGAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGTTAACAACAAGCACCGTTTTATCGTACTCAGGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGTGATACAAATCAACCACTTCGGAGGCGGTTATCGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGTGTCTGACAGGTTGCGAGCCTGTTGTCACAGCAGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTTGTACGGTACCACATACGCGAAACCAAGTGTCTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTTGAAGTGAACATTTTTGAATAAATCGCGTTTGTAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAATTTCGTAGTGCTATCAGCGCAATAACTGTAACGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTTGCATGAGTTTAAGAGGGAGCAAAAATAAATGACAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCCGTAGAAAACATTGTAAAAATTTCGGGCGTGGCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATCGCTTGCGCCTGTGCAAGTGCGTTTTGTGCCTTTTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAGCTAATGCTATATCGTAAGTTTGAGCCAACACTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATACAACGGTGTGTTTGTTTTTCCCCCGAATTTGATAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATACTAGCAATATGACAACGGAAGAAACCGTAAACCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGTTTACATACGCATTATATCACATATTTGCCCGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCTTAACGCGTCCATTTCTTCCGCTGTCGCGCCCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTATCGTGTACGATATTTTCCGTATCGGAAATCTTGTCTCTCTCCACACGGGGAGAGTGGATTGAAATACTTAACGCGGCTTGATACTGTTCGGGTGTCAAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGACCGTCCAATTATTTTCTTTCATAGCCTTTTCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGATAACCCACAAACTTTTAATATATCTATAATTTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATACGTTCACACCCCCACAAATGAATTTTTGTAGTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTGTGTTCACGCCCGCTTTTTCCATTTGTGCAATTAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGTATGATTGCACATAAAACGTGTGGAAAAATTGTTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGTCCACGCGGTTGTGAATGTGGTTTTAAACCACGTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCCGCCAACACTGCATAATGTTCTGGCGAAAGAAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTTTGCTTCTGCGCTGTTTTCGCCGTACTGTTCAGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATATAAACGGTCCAGACGTATCCTTAAAATGGCAGAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATCATTGGGAATCATCTCCTTTGCAAAAATGGGTTAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCTTCTGTTTTCATGCCATGTTTGTTGGATATTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTTTGCAGTTGAGTTCCAGTGCCTTGCGTACCCGGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTTAAAACATTTCGGGCAGAAAAAACTTAGAGTTGTGTCTCTCCCCACACGGGGGGAGTGGATTGAAATTGCTATGCCCTCAAATGTTTTCGCACGATTTCTAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATATTGGATTTACCGTCAAGCATATCTGCTTTCGGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCTGAACCGCCTCCGCCTGTGCCATCGCCATAAGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTTTATGAACTTAAACAATCCCCAAAAGTTGTCCGCAGTCTCTCCCCACACGGGGAGAGTGGATTGAAATGACCAGTCTGTACCGTTTGAACACAGGTCTATCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAATATGTATATTGCTCGCGCTTGATGAATCTACGCCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAGCAGTTACTACGCCGCCCGAAGTTACGGTTGCGTCTCTCCCCACACGGGGAGAGTGGATTGAAATATCAACGGTTAGTGTCATAGTGCTGTTACCGTTGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAATAATATATATCCTGGACTAACTGAGGTTCAGGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATTCTCTAACCCAGCTCAGAAGTTCAAAAAGACAAAGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATAAATCAGCTATGCCCGATGTGGTATTGTAGCCTGGTCTCTCCCCACACGGGGAGAGTGGATTGAAATATTCGTCCGCCCCCTCGATGATTAGTGTGCAACGTCTCTCCCCACACGGGGAGAGTGGATTGAAAG

>NC_014833|5|5|1313206-1317474|CRISPRCasFinder
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCGTCACAAGGTAGCAAGACTGCGTGTTGAGAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TAGCATAGCCTTATCATTACAATTAAGTTTGCTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTCCTGCAAGTATCTGTGCGGTCTGTGCTGTCTG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTGAGTTGTTGAGCCAAGGGTAGAGGTAATCCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCAGACCAACGTTCTCGCGCTGTGCCTGTGCCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CGACCTCTCACATAGCTATCTATGGTATCGCATA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCGATACACTGCTTGATAATCTTACCGTGTTATG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCAGACCAACGTTCTCGCGCTGTGCCTGTGCCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCCATTCAAGGTCAAAGTATATCGGATATTCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATAGCGTGTGCCGTTCTGCTTTACCTTATCAACGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GCAAGGGTGCGGATGATCTTCGTGGGTATCTGAT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACTGCACAGCCCATAAGTATCTCGGGGCAGTGAAC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCGGCTTTGGTGCGCACCTAGAAAAAGGTGAAGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AACGCTGTGATGATCTGCAGGATAACGCGGAAGTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGCGGTAGAATATCGCGGTTGATAGCCTCGATC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TATCGTCCAGAAAAACATAGCATAAGCCTGTGGCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTCTGCCCTTAGGTTTGCAATAAACGTTTCCC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AAGATATCCCTGTATCTGATTTCCAAAGCTTACA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TATGCCCTCCCGCTTGGTGTGCTCTATCTTCCGCTTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGTTATATAATGCTTTGTGCCGTTCTTATCTTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CATAGCGTAACAATTGCCGCTATCAAGCCCGCTAT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AACCTTAGAGAACACGCCACCTTCGCCGAGGATGA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTTAACAACAAGCACCGTTTTATCGTACTCAGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTGATACAAATCAACCACTTCGGAGGCGGTTATCG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTGTCTGACAGGTTGCGAGCCTGTTGTCACAGCAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTGTACGGTACCACATACGCGAAACCAAGTGTCT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTGAAGTGAACATTTTTGAATAAATCGCGTTTGTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATTTCGTAGTGCTATCAGCGCAATAACTGTAAC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTGCATGAGTTTAAGAGGGAGCAAAAATAAATGACA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCCGTAGAAAACATTGTAAAAATTTCGGGCGTGGC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CGCTTGCGCCTGTGCAAGTGCGTTTTGTGCCTTTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGCTAATGCTATATCGTAAGTTTGAGCCAACACT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ACAACGGTGTGTTTGTTTTTCCCCCGAATTTGATA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ACTAGCAATATGACAACGGAAGAAACCGTAAACC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTTTACATACGCATTATATCACATATTTGCCCG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTTAACGCGTCCATTTCTTCCGCTGTCGCGCCC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TATCGTGTACGATATTTTCCGTATCGGAAATCTT
GTCTCTCTCCACACGGGGAGAGTGGATTGAAAT	ACTTAACGCGGCTTGATACTGTTCGGGTGTCAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACCGTCCAATTATTTTCTTTCATAGCCTTTTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GATAACCCACAAACTTTTAATATATCTATAATTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ACGTTCACACCCCCACAAATGAATTTTTGTAGT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTGTTCACGCCCGCTTTTTCCATTTGTGCAATTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTATGATTGCACATAAAACGTGTGGAAAAATTGTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTCCACGCGGTTGTGAATGTGGTTTTAAACCACGT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCCGCCAACACTGCATAATGTTCTGGCGAAAGAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTGCTTCTGCGCTGTTTTCGCCGTACTGTTCAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATAAACGGTCCAGACGTATCCTTAAAATGGCAGA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CATTGGGAATCATCTCCTTTGCAAAAATGGGTTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTTCTGTTTTCATGCCATGTTTGTTGGATATT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTGCAGTTGAGTTCCAGTGCCTTGCGTACCCGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTAAAACATTTCGGGCAGAAAAAACTTAGAGTTGT
GTCTCTCCCCACACGGGGGGAGTGGATTGAAAT	TGCTATGCCCTCAAATGTTTTCGCACGATTTCTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATTGGATTTACCGTCAAGCATATCTGCTTTCGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTGAACCGCCTCCGCCTGTGCCATCGCCATAAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTATGAACTTAAACAATCCCCAAAAGTTGTCCGCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACCAGTCTGTACCGTTTGAACACAGGTCTATC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATATGTATATTGCTCGCGCTTGATGAATCTACGCC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGCAGTTACTACGCCGCCCGAAGTTACGGTTGC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATCAACGGTTAGTGTCATAGTGCTGTTACCGTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATAATATATATCCTGGACTAACTGAGGTTCAGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTCTAACCCAGCTCAGAAGTTCAAAAAGACAAAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AAATCAGCTATGCCCGATGTGGTATTGTAGCCTG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATTCGTCCGCCCCCTCGATGATTAGTGTGCAAC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAG

>NC_014833|5|1|1313206-1317474|CRT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCGTCACAAGGTAGCAAGACTGCGTGTTGAGAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TAGCATAGCCTTATCATTACAATTAAGTTTGCTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTCCTGCAAGTATCTGTGCGGTCTGTGCTGTCTG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTGAGTTGTTGAGCCAAGGGTAGAGGTAATCCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCAGACCAACGTTCTCGCGCTGTGCCTGTGCCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CGACCTCTCACATAGCTATCTATGGTATCGCATA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCGATACACTGCTTGATAATCTTACCGTGTTATG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCAGACCAACGTTCTCGCGCTGTGCCTGTGCCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCCATTCAAGGTCAAAGTATATCGGATATTCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATAGCGTGTGCCGTTCTGCTTTACCTTATCAACGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GCAAGGGTGCGGATGATCTTCGTGGGTATCTGAT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACTGCACAGCCCATAAGTATCTCGGGGCAGTGAAC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGCGGCTTTGGTGCGCACCTAGAAAAAGGTGAAGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AACGCTGTGATGATCTGCAGGATAACGCGGAAGTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGCGGTAGAATATCGCGGTTGATAGCCTCGATC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TATCGTCCAGAAAAACATAGCATAAGCCTGTGGCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTCTGCCCTTAGGTTTGCAATAAACGTTTCCC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AAGATATCCCTGTATCTGATTTCCAAAGCTTACA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TATGCCCTCCCGCTTGGTGTGCTCTATCTTCCGCTTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGTTATATAATGCTTTGTGCCGTTCTTATCTTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CATAGCGTAACAATTGCCGCTATCAAGCCCGCTAT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AACCTTAGAGAACACGCCACCTTCGCCGAGGATGA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTTAACAACAAGCACCGTTTTATCGTACTCAGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTGATACAAATCAACCACTTCGGAGGCGGTTATCG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTGTCTGACAGGTTGCGAGCCTGTTGTCACAGCAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTGTACGGTACCACATACGCGAAACCAAGTGTCT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTGAAGTGAACATTTTTGAATAAATCGCGTTTGTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATTTCGTAGTGCTATCAGCGCAATAACTGTAAC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTGCATGAGTTTAAGAGGGAGCAAAAATAAATGACA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCCGTAGAAAACATTGTAAAAATTTCGGGCGTGGC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CGCTTGCGCCTGTGCAAGTGCGTTTTGTGCCTTTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGCTAATGCTATATCGTAAGTTTGAGCCAACACT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ACAACGGTGTGTTTGTTTTTCCCCCGAATTTGATA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ACTAGCAATATGACAACGGAAGAAACCGTAAACC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTTTACATACGCATTATATCACATATTTGCCCG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTTAACGCGTCCATTTCTTCCGCTGTCGCGCCC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TATCGTGTACGATATTTTCCGTATCGGAAATCTT
GTCTCTCTCCACACGGGGAGAGTGGATTGAAAT	ACTTAACGCGGCTTGATACTGTTCGGGTGTCAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACCGTCCAATTATTTTCTTTCATAGCCTTTTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GATAACCCACAAACTTTTAATATATCTATAATTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ACGTTCACACCCCCACAAATGAATTTTTGTAGT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTGTTCACGCCCGCTTTTTCCATTTGTGCAATTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTATGATTGCACATAAAACGTGTGGAAAAATTGTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTCCACGCGGTTGTGAATGTGGTTTTAAACCACGT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCCGCCAACACTGCATAATGTTCTGGCGAAAGAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTGCTTCTGCGCTGTTTTCGCCGTACTGTTCAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATAAACGGTCCAGACGTATCCTTAAAATGGCAGA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CATTGGGAATCATCTCCTTTGCAAAAATGGGTTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTTCTGTTTTCATGCCATGTTTGTTGGATATT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTGCAGTTGAGTTCCAGTGCCTTGCGTACCCGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTAAAACATTTCGGGCAGAAAAAACTTAGAGTTGT
GTCTCTCCCCACACGGGGGGAGTGGATTGAAAT	TGCTATGCCCTCAAATGTTTTCGCACGATTTCTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATTGGATTTACCGTCAAGCATATCTGCTTTCGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTGAACCGCCTCCGCCTGTGCCATCGCCATAAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTATGAACTTAAACAATCCCCAAAAGTTGTCCGCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACCAGTCTGTACCGTTTGAACACAGGTCTATC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATATGTATATTGCTCGCGCTTGATGAATCTACGCC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGCAGTTACTACGCCGCCCGAAGTTACGGTTGC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATCAACGGTTAGTGTCATAGTGCTGTTACCGTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATAATATATATCCTGGACTAACTGAGGTTCAGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTCTAACCCAGCTCAGAAGTTCAAAAAGACAAAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AAATCAGCTATGCCCGATGTGGTATTGTAGCCTG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATTCGTCCGCCCCCTCGATGATTAGTGTGCAAC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAG

>NC_014833|5|1|1315633-1317474|PILER-CR
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TATCGTGTACGATATTTTCCGTATCGGAAATCTT
GTCTCTCTCCACACGGGGAGAGTGGATTGAAAT	ACTTAACGCGGCTTGATACTGTTCGGGTGTCAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACCGTCCAATTATTTTCTTTCATAGCCTTTTC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GATAACCCACAAACTTTTAATATATCTATAATTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ACGTTCACACCCCCACAAATGAATTTTTGTAGT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TGTGTTCACGCCCGCTTTTTCCATTTGTGCAATTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTATGATTGCACATAAAACGTGTGGAAAAATTGTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GTCCACGCGGTTGTGAATGTGGTTTTAAACCACGT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCCGCCAACACTGCATAATGTTCTGGCGAAAGAA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTGCTTCTGCGCTGTTTTCGCCGTACTGTTCAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATAAACGGTCCAGACGTATCCTTAAAATGGCAGA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	CATTGGGAATCATCTCCTTTGCAAAAATGGGTTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTTCTGTTTTCATGCCATGTTTGTTGGATATT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTGCAGTTGAGTTCCAGTGCCTTGCGTACCCGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTAAAACATTTCGGGCAGAAAAAACTTAGAGTTGT
GTCTCTCCCCACACGGGGGGAGTGGATTGAAAT	TGCTATGCCCTCAAATGTTTTCGCACGATTTCTA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATTGGATTTACCGTCAAGCATATCTGCTTTCGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTGAACCGCCTCCGCCTGTGCCATCGCCATAAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TTTATGAACTTAAACAATCCCCAAAAGTTGTCCGCA
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	GACCAGTCTGTACCGTTTGAACACAGGTCTATC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATATGTATATTGCTCGCGCTTGATGAATCTACGCC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AGCAGTTACTACGCCGCCCGAAGTTACGGTTGC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATCAACGGTTAGTGTCATAGTGCTGTTACCGTT
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AATAATATATATCCTGGACTAACTGAGGTTCAGG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	TCTCTAACCCAGCTCAGAAGTTCAAAAAGACAAAG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	AAATCAGCTATGCCCGATGTGGTATTGTAGCCTG
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAT	ATTCGTCCGCCCCCTCGATGATTAGTGTGCAAC
GTCTCTCCCCACACGGGGAGAGTGGATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_157865473.1\|1317537_1318014_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497841.1\|1323580_1325143_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497837.1\|1312754_1313045_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_014833.1\|WP_013497839.1\|1322089_1323034_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497835.1\|1311057_1311717_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|187768
NC_014833.1\|WP_013497832.1\|1307620_1308370_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187782
NC_014833.1\|WP_013497831.1\|1305018_1307367_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_014833.1\|WP_043550584.1\|1328738_1328921_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_028504470.1\|1320589_1321453_-\|SUKH-3-domain-containing-protein	unknown	unknown	gnl\|CDD\|379608
NC_014833.1\|WP_013497836.1\|1311718_1312750_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_014833.1\|WP_013497828.1\|1301951_1302893_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497840.1\|1323125_1323467_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013483393.1\|1326433_1326790_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_014833.1\|WP_013483393.1\|1319669_1320026_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_014833.1\|WP_013497827.1\|1301446_1301842_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497833.1\|1308353_1310195_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NC_014833.1\|WP_013483496.1\|1320019_1320337_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|274987
NC_014833.1\|WP_013497834.1\|1310198_1311056_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NC_014833.1\|WP_013497830.1\|1303617_1304337_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013483805.1\|1318065_1319577_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_013497837.1\|1312754_1313045_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.33114e-30
NC_014833.1\|WP_013483393.1\|1326433_1326790_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	9.05932e-54
NC_014833.1\|WP_013497835.1\|1311057_1311717_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	7.60719e-34
NC_014833.1\|WP_013497832.1\|1307620_1308370_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.11237e-81
NC_014833.1\|WP_013497831.1\|1305018_1307367_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.12866e-46
NC_014833.1\|WP_028504470.1\|1320589_1321453_-\|SUKH-3-domain-containing-protein	gnl\|CDD\|379608	pfam14433, SUKH-3, SUKH-3 immunity protein. This family belongs to the SUKH superfamily and functions as immunity proteins in bacterial toxin systems.	0.0009492
NC_014833.1\|WP_013483496.1\|1320019_1320337_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|274987	TIGR04111, conserved_hypothetical_protein, phage-associated protein, BcepMu gp16 family. Members of this protein family occur in Burkholderia phage BcepMu, Pseudomonas phage B3, and Burkholderia phage KS10, and many bacterial putative prophage regions. The member from Burkholderia phage BcepMu is named gp16. Homology suggests DNA-binding activity. [Mobile and extrachromosomal element functions, Prophage functions].	0.000537696
NC_014833.1\|WP_013483393.1\|1319669_1320026_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	9.05932e-54
NC_014833.1\|WP_013497833.1\|1308353_1310195_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.08258e-141
NC_014833.1\|WP_013497836.1\|1311718_1312750_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_014833.1\|WP_013497834.1\|1310198_1311056_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	6.53052e-123
NC_014833.1\|WP_013483805.1\|1318065_1319577_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	7.63877e-102

>NC_014833.1|WP_013497837.1|1312754_1313045_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDVSTADNAGKKRLRRVAKQCVNYGVRVQNSVFECELDPAQCRLLKQKLTEEIDETKDSLRFYYLGNIKKAKVEHVGSKQTLKVDEPLIF
>NC_014833.1|WP_013497836.1|1311718_1312750_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLLNTLYITSPDRYLSLDGENVVVQADGKEIGRVPLHNLERIMTFGYTGASPALMGKCAANGIELIFMSGSGKFLARVEGEVNGNVLLRRQQYRYADESKVSLDISKNIICAKLFNSRWTIERTLRDHPMRIDADKFDNCSQQLKKSIDNARKADDIDTLRGIEGEAAQIYFSVFDDMILQQKDDFSFKTRNKRPPKDTVNALLSFAYSLATSMCTSALEAVGLDPYVGFMHTDRPGRRSLALDLVEEMRSPLCDRFVLTVINKKIISAHDLEKREDGAVILTDNGRRAFITAWQKRKDDELKHPFLDEKIEWGTVPYAQALLLARYIRGDLDAYPPFMWK
>NC_014833.1|WP_013497835.1|1311057_1311717_+|CRISPR-associated-protein-Cas4
MYSEDEYLMLSGIQHFVFCRRQWALIHIEQQWEENYRTADGQVMHRNVHDADFHEKRGNTIITRAMAVSSSKLGISGECDVVEFHGCKNGIGLFGVEGRYEVIPIEYKRGSPKENDSDIMQLAAQAMCLEEMLCCTIDTGYLYYGETHRRTKVIIDAELRERTEKAIEEMHELYRKKYTPKVKRTKACNACSLKNICLPVLCSKKSAADYIKDMLGKEE
>NC_014833.1|WP_013497834.1|1310198_1311056_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MAVLQNKIDFSVILTAKNANPNGDPLNGNRPRENYDGFGEISDVCIKRKIRNRLQDMGEKIFVQSDDRCGDGFKSLHDRAKGCETLAALSKAKNTDRDEYAKAACAEWIDVRSFGQVFAFKGDSVSVGVRGPVSIQMAESISPVDIVSMQITKSVNGESGKESKASDTMGSKHRVDFGLYVFHGSINVQLAEKTGFTEEDAEKIHEALETLFENDCSSARPEGSMEVRRVYWYKHECKTPTNSSAKVHRLLKVTLRDGIDRPKCFEDYDITLDKLEGLDPEIFEG
>NC_014833.1|WP_013497833.1|1308353_1310195_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWTNELLEVYNNAVKIKAEPNKPKLLPISHTMVKANIHITLTEDGELDNTGIKEITSEDDENTIIPDTGKAKTGIYPPPYPLNESLRYLAGDFNEYISDNIKSNERNHQDYIEQLKDWKDSEYSHPALNAIYTYITKNTLIYDCICNNVLLLDDKTGKLKEKQLGVSVDKCFVRFSVQYADMQHEPRTWKDETLYNSFIDYLNSNAVEKRLCYATGDYLPITYTHPYGIVKSNARAKLISSNDDKNYTYRGRFSTKEEAFAVSYDYSQKVHNALKWLIGRQSFSFDSLTLVVWNSALDFVPNITENVWGDVEIEEYSSKPIFSEMLRKNILGGKAEFDPNSKVMVMGLDAATTGRLSISMYTELAESEFAKYLEFWHTSTAWKRKKYIKDKYEYILDSCSLPQIANCLYGTEQNGRLECDKKVLGDTILRLLPCVTERRKLPRDIVQTICNKASNPLAFDKEYNHMMIVENACALIRKEYSDYNKGEIKMAYDPTCTDRSYLFGCLLAIADKAERDTYEKDEKRITNARRYWNAFSSRPYQTWQIIEEKIEPYLEKDPRLMTKYTKHINDIMAKMSPDTFKDNSKLSPLYLIGFHHYNTLLWKGSEDNNKEE
>NC_014833.1|WP_013497832.1|1307620_1308370_+|type-I-C-CRISPR-associated-protein-Cas5
MKKHRNTVEFYVHGKYALFSDVLTRVGGEKCSYTIPTYEALKGILQSVYFKPTITWFIDEVRIMNPIKTVRKGIRPIKYDGGNDLAYYTYLEDVCYQVRAHFEWNMNRPELEQDRNEHKHHNIAKRMIERGGRRDIFLGTRECQAYVEPCVFGEGEGAYDNVSMDMAFMYYGIIYPDEAEKEEDKGYMTVCLWQPKMKDGIIEFVRPSEIAPEHKRHIKKMEMKKFGKELDNFTGLEEFEGGEFDELDE
>NC_014833.1|WP_013497831.1|1305018_1307367_+|CRISPR-associated-helicase/endonuclease-Cas3
MYTAHIRENDKVIQTVSEHSQNTALLAERFLTSSNIGSVGYLCGLLHDAGKLLKDFDDYINKRNKMTRGSIDHAYAGAKYLISIASKDKANIAAISMAHTIVSHHGIHDWIDNDNYDYFSKRISYDKGYDEILNNLNEIIGDININDLFEKATKEWFDVAKMIRGFSKTKEEKEEKIDNTKFYFYLGMLERLIQSALIDADRTDTADFMSGVESAEETDTSLLWEQMDSRMNEKLKSFENKTDAISLQRRSISDRCAAFADHKVGVCRLIVPTGGGKTLSSLRFAIKQCKNYGMKKIFYIAPFMSILEQNSDIIGELSGEEDFLEHHSNIISDIDNENELEKYLLYSERWTKPVIATTMVQFLNTLFSAKTSSVRRMHCLCNSVIIIDEVQSVPLKCTHLFSLAVNFLTKICGCSVVLCSATQPTFERNEHSLMRDERADMIENYAEDFEVFKRTEMIPAMQKYGYDIEEATLLCEQKFEENGNLLLIVNTKKQAREMYTRLKDKLGEKAHIIHLSTNMCPAHRKESIDDLKEKLEHGVPVVCVTTQLIEAGVDISFSCVVRALAGLDNAAQAAGRCNRNGEKGRICPVYLINFKNEPLGNLTEIKTAQDISQHVIRNNENADLLSVDIQSSYFEQLFSQNKEKLDYPANGTTLLELLSTNKGKAEAHDLKPDMLLQAFKTAGNIFEVIDSHTENVIVPYNDEAESFISRLNDDLTPQEAAEILRKAQKYTVSVYMGTKKALEEKGAIHITKNNNIIVLDKRFYNSEFGITTEGAERETLMY
>NC_014833.1|WP_013497830.1|1303617_1304337_-|hypothetical-protein
METYLNLIPNLDNIICEVLKEEFDVKVCEKGHFWFTPWEDHCRKVVMFYPLKGPRGPLYWGYNFDFIPWESCFLGVNYKPWNTTGKLVYHRTEKAVKIDHRGSPLPYIGYNFGNPDAYSIEEHHAFREKYFIQAYGNDTPENIEKIKAVVRRNIPFMLDWFERVKTPENIIGECTRIIAEDENEHCFPYSYYWVRGFLKAKLHDLEGALSDIAYVYKRFEPPAEIPEIVIKALNKIDKI
>NC_014833.1|WP_013497828.1|1301951_1302893_-|hypothetical-protein
MNCLQYIELLILGRKLSKNTEFKFRMHIFKKFFIPGKTTTQIPDKNKKIKRYVDIYLHPLELEFENDKSVYVAALIAIFHEFHHVKQFYDIKEGTAKPQIAISLLASQNNKKFYDNNYKYLPYEIEAEMIGVMDAYRYLLKKSDNYAFQAVKNYIKSKITHEDSRYKQRGFNLSKINSIADIESIFKKNIQHSFNQELNMNPIYDAFSEEISMCDTTFQSNLIYKLLKIIGKEKIKHIFNLLESGMPQLNLIAAYVLEEHPDYSIFFNKYNIQPFSNYTEAYKKFCSEIEHNVLKNEEKRILFKELLNQLIQQ
>NC_014833.1|WP_013497827.1|1301446_1301842_+|hypothetical-protein
MVVMNPKGEVVIAHHGKKELRVKFCKDGIRARSELGYKSFYLYNKDMYIRSTDKGYVTENMQFALIRIERFLINAINVIGAGFEENAIPSESHKAAVLLMQNVSDTKMTSIERWADFDKKVERLGGWFGNW
>NC_014833.1|WP_157865473.1|1317537_1318014_-|hypothetical-protein
MNREYHILPEEDYFGQGMIDPQDAAEVAHFLWERTWIIDDYLERSDLPEEHMEILKSWKGCITGRFIIERHWKKGSVFISIDDNSVFLVNGIVSSWEEMLRNAPMPTLLDAALLPFKNAIISDGLVSVMPIIFGPNSKADFKEIYMDAKRNGEIKARI
>NC_014833.1|WP_013483805.1|1318065_1319577_-|IS66-family-transposase
MSEPNMTSEIVSLRNENAVLKEELALANQQLAWFRKQIFGRKTEQTSVVMEKEFGVQLSMFGNNEEKSAAKSAETITVPEHKRKKKRTHDEWMNNLPVKEEHHKIDNPVCEICGAEMEELTPEKAYDELIFTPPKYHIRRHIVHKYKCPECGEKPEERDEPCHIIRAPYPHAMIPGSYCSPELLAHIIYEKYAKSVPLHRQEKDFNSKNIPLLKATMSNWVGTAAEKWCLPIVEKMHEMLIAGQMIHADETTVQVLHEEGRKPTTTSRMWVYCNGKMNDRSIIIFDYQPTRKGEHASNFLKGFIGYLICDGYDAYNAVEGAKRCGCMTHARRGFIQALPNDQKLHSTSVAAKAVEYFNKIYHEENLLADSSTEYRYKQRLVKVKPLLDEFFAWLENVQVSGKGKLTDAVRYALNERKYLYTFLENGDVPIDNNRAENAIRPFALGRKNWLFSNTANGARSSATLYSIISTAQANGVDAEKYLTELFSQPAGTILLPWREENET
>NC_014833.1|WP_013483393.1|1319669_1320026_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNDLAADAQVYLVTGYTDLRRGIDGLATIVQAQLRLDPFSKALFLFCGRRCDRIKGLLWEGDGFLLLYKRLDNGRFQWPRSETEAVMLTSQQIRWLLEGLKIEQPKAIREGKPGALY
>NC_014833.1|WP_013483496.1|1320019_1320337_-|IS66-family-insertion-sequence-hypothetical-protein
MDKTTSITTIKKEMQLQEWSAQIKAQQASGLTIREWCKEKGIKPNTYYNRLRKVREKYIENSPTIVPVSVPCSNENIRIEKNGLQISLPADISADTLTALVHELC
>NC_014833.1|WP_028504470.1|1320589_1321453_-|SUKH-3-domain-containing-protein
MKGSEMSIIIDDQYRHSPRYEKHFNVFCEGLEKHFNDIPVFDAAMQFYKEYHFIRYLSDHNGVTCGSFEYDDTNLHLNGIRLEEAVRKLVKDNGIKYLPAAVVYLKKAFFRFILINENGEFYLDDGTYLGTDYEKIVESILNGEKEIVPILNDRIYTSLERHGWDPDKIIDTAPIEEKYRELGFSFFPAANKFFEVIPIGKYRIWIPKSDDDCYVGFYPNKRMKDPKEFQNEIGEDLLTIAAKREANFFISESGKFYAQYEFTREMFYVTDDLYLFIYYLLINRNGF
>NC_014833.1|WP_013497839.1|1322089_1323034_-|hypothetical-protein
MNKELATFEKDYLSYCDIYDNAVKKYNTNADKINNFIADVDRFNVFSEVHNIEHRSEINRNFDEYRKSNDDISVISNDVKKINTETKKLEESYLPICETAYDTIVNNYNDLVNDYNSLKEKTSLDFIKDIPEYKTINDSELYVLDETSFTEEKLIDEISKISDNINDISQLYIVSEQITAPSKDFIYERLKDVESITSTKAVTTYYDPNKLLGEEGGYTSCVYFTVDNIAVSDVNGIDAAHKGVDGGGSVEVYATLDDALKRCDYLSQFDGTLLYSGSYTIVGTMVIRTSYKLSNEEQIQLTDDIINSLTEIKE
>NC_014833.1|WP_013497840.1|1323125_1323467_-|hypothetical-protein
MNLQDLDDILSAHTLVEKDKIMNYTFAVTGLSFLKIRDILIVKGNIIFEDLENKVYVAFIRSGFMKKSDAKAAIHLYNEQLLISIYAKEGIVNQRICEGAINELEKSLKDYIG
>NC_014833.1|WP_013497841.1|1323580_1325143_-|hypothetical-protein
MNKRIISIILSCSILLQNSQLAVFAQEESSSLPNDNYTVDISDNVDITSIVIANRMTGADVRAQRKFTAAQGHGFAAERGNNLIDKIKGSNAIVIGDNNVKNGADRIIIQKTGENIFIQDKYYQSAPASINACFDEEEIFRYFDSDGKPMQIEVPKDQYDNAVDLMKEKIKNGSVPGITDPEEAERIVRKGNLTYKQAVNIAKAGNIDSLKYDATNGIVSSSAAFGIDTLLNFAVRVNSGEEYSDAIKDSAIDGLKAGGMQFATAVIAGQLAKTNVKNVFRPSATALVDALGDDFAKTLTKTMEKELIEEGAESLGKTAAKKAAVELISSNALVDTVSLIVFTVPDGVKLFNGKISKKQFIKNFAVAGVSTVAGAAGGYAGGIIGSLVVPGVGTLPGAIIGSVLIGGGASIAADAIADYITDDDADEMYEIIQNKFADKCEEYIVTESEATNIAKELSNKLDEDVFEKMYQSNDRSKFADDLLEPLFEKEVKKRPKVKVPTEDEMRASLLEELNGVVFLH
>NC_014833.1|WP_013483393.1|1326433_1326790_+|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNDLAADAQVYLVTGYTDLRRGIDGLATIVQAQLRLDPFSKALFLFCGRRCDRIKGLLWEGDGFLLLYKRLDNGRFQWPRSETEAVMLTSQQIRWLLEGLKIEQPKAIREGKPGALY
>NC_014833.1|WP_043550584.1|1328738_1328921_+|hypothetical-protein
MLRNAPMPTLLDAALLPFKNAIISDGLVSVMPIIFGPNSKADFKEIYMDAKRNGEIKARI

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Crispr_ID: NC_014833_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_6

1325369-1325938

TypeI

Consensus_repeat	Method
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	PILER-CR
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CRISPRCasFinder
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CRT
ATTGGAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACA	PILER-CR

8 spacers

cas2,cas1

The CRISPR arrays of NC_014833_6

>merge|NC_014833|6|1325369-1325938|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGACATTTTGGCGAAAGTCAGACAACAAGGCGAGTAAAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACCCTTGACAGATATCAACTCACGTTCGGTCTTGTTGCATTTCAATCCACTCTCCCCGTGTGGGGAGAGACTTGTATACCCTCGCAACGTGCGAGGGATACGGCATTTCAATCCACTCTCCCCGTGTGGGGAGAGACAGCATGGGGTTACGATATGTTAATTGCATTACTGATTTCAATCCACTCTCCCCGTGTGGGGAGAGACAAAAGGTTATAGCCCACAAAGATGAGATAATCGAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACGAAGGATGATCCCGATTGCAAGTACTGCATTTGGATTTCAATCCACTCTCCCCGTGTGGGGAGAGACCAATGGGACTGAACAAATGTATTTTTCTTGGGAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACAGAGTCGCAGTTTGGCAACAAAGACCATAGTGGCATTTCAATCCACTCTCCCCGTGTGGGGAGAGACA

>NC_014833|6|2|1325369-1325670|PILER-CR
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	ATTTTGGCGAAAGTCAGACAACAAGGCGAGTAAA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CCTTGACAGATATCAACTCACGTTCGGTCTTGTTGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	TTGTATACCCTCGCAACGTGCGAGGGATACGGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AGCATGGGGTTACGATATGTTAATTGCATTACTG
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGACAAAAGGTTATAGCCCACAAAGATGAGATAATCGAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACGAAGGATGATCCCGATTGCAAGTACTGCATTTGGATTTCAATCCACTCTCCCCGTGTGGGGAGAGACC	AATGGGACTGAACAAATGTATTTTTC
TTGGGAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACA	GAGTCGCAGTTTGGCAACAAAGACCAT


>NC_014833|6|6|1325369-1325937|CRISPRCasFinder
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	ATTTTGGCGAAAGTCAGACAACAAGGCGAGTAAA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CCTTGACAGATATCAACTCACGTTCGGTCTTGTTGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	TTGTATACCCTCGCAACGTGCGAGGGATACGGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AGCATGGGGTTACGATATGTTAATTGCATTACTG
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AAAAGGTTATAGCCCACAAAGATGAGATAATCGA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	GAAGGATGATCCCGATTGCAAGTACTGCATTTGG
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CAATGGGACTGAACAAATGTATTTTTCTTGGGA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AGAGTCGCAGTTTGGCAACAAAGACCATAGTGGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC

>NC_014833|6|2|1325369-1325937|CRT
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	ATTTTGGCGAAAGTCAGACAACAAGGCGAGTAAA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CCTTGACAGATATCAACTCACGTTCGGTCTTGTTGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	TTGTATACCCTCGCAACGTGCGAGGGATACGGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AGCATGGGGTTACGATATGTTAATTGCATTACTG
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AAAAGGTTATAGCCCACAAAGATGAGATAATCGA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	GAAGGATGATCCCGATTGCAAGTACTGCATTTGG
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CAATGGGACTGAACAAATGTATTTTTCTTGGGA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AGAGTCGCAGTTTGGCAACAAAGACCATAGTGGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC

>NC_014833|6|3|1325766-1325938|PILER-CR
	ATTTTGGCGAAAGTCAGACAACAAGGCGAGTAAA
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	CCTTGACAGATATCAACTCACGTTCGGTCTTGTTGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	TTGTATACCCTCGCAACGTGCGAGGGATACGGC
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGAC	AGCATGGGGTTACGATATGTTAATTGCATTACTG
ATTTCAATCCACTCTCCCCGTGTGGGGAGAGACAAAAGGTTATAGCCCACAAAGATGAGATAATCGAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACGAAGGATGATCCCGATTGCAAGTACTGCATTTGGATTTCAATCCACTCTCCCCGTGTGGGGAGAGACC	AATGGGACTGAACAAATGTATTTTTC
TTGGGAATTTCAATCCACTCTCCCCGTGTGGGGAGAGACA	GAGTCGCAGTTTGGCAACAAAGACCAT
AGTGGCATTTCAATCCACTCTCCCCGTGTGGGGAGAGACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_157865473.1\|1317537_1318014_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497841.1\|1323580_1325143_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497837.1\|1312754_1313045_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_014833.1\|WP_013483393.1\|1326433_1326790_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_014833.1\|WP_013497846.1\|1333861_1334581_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_014833.1\|WP_013497848.1\|1336400_1340327_-\|fibronectin-type-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|238020
NC_014833.1\|WP_043550584.1\|1328738_1328921_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497845.1\|1333693_1333852_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_037304971.1\|1334582_1335713_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497850.1\|1342743_1343838_+\|leucine-rich-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|275383
NC_014833.1\|WP_013497849.1\|1340701_1342483_+\|DUF4832-domain-containing-protein	unknown	unknown	gnl\|CDD\|374373
NC_014833.1\|WP_028504470.1\|1320589_1321453_-\|SUKH-3-domain-containing-protein	unknown	unknown	gnl\|CDD\|379608
NC_014833.1\|WP_013497836.1\|1311718_1312750_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_014833.1\|WP_013497839.1\|1322089_1323034_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013483496.1\|1320019_1320337_-\|IS66-family-insertion-sequence-hypothetical-protein	unknown	unknown	gnl\|CDD\|274987
NC_014833.1\|WP_013483393.1\|1319669_1320026_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_014833.1\|WP_013497840.1\|1323125_1323467_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013497844.1\|1331463_1333041_-\|RICIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|379501
NC_014833.1\|WP_013483805.1\|1318065_1319577_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NC_014833.1\|WP_013497843.1\|1329130_1330702_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|313108

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_013497837.1\|1312754_1313045_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.33114e-30
NC_014833.1\|WP_013483393.1\|1326433_1326790_+\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	9.05932e-54
NC_014833.1\|WP_013497846.1\|1333861_1334581_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.12945e-45
NC_014833.1\|WP_013497848.1\|1336400_1340327_-\|fibronectin-type-III-domain-containing-protein	gnl\|CDD\|238020	cd00063, FN3, Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.	9.90197e-05
NC_014833.1\|WP_013497849.1\|1340701_1342483_+\|DUF4832-domain-containing-protein	gnl\|CDD\|374373	pfam16116, DUF4832, Domain of unknown function (DUF4832). This family consists of uncharacterized proteins around 200 residues in length and is mainly found in various Bacteroides and Capnocytophaga species. The function of this family is unknown. Distant homology analysis suggests a possible similarity of proteins from this family to TIM barrel glycoside hydrolases and, subsequently its involvement in carbohydrate metabolism.The domain lies downstream of glycosyl hydrolases 42 suggesting that as a domain it might represent the carbohydrate-binding region of the enzyme.	4.8489e-57
NC_014833.1\|WP_013497850.1\|1342743_1343838_+\|leucine-rich-repeat-domain-containing-protein	gnl\|CDD\|275383	sd00036, LRR_3, leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	5.85366e-34
NC_014833.1\|WP_028504470.1\|1320589_1321453_-\|SUKH-3-domain-containing-protein	gnl\|CDD\|379608	pfam14433, SUKH-3, SUKH-3 immunity protein. This family belongs to the SUKH superfamily and functions as immunity proteins in bacterial toxin systems.	0.0009492
NC_014833.1\|WP_013497836.1\|1311718_1312750_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_014833.1\|WP_013483805.1\|1318065_1319577_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	7.63877e-102
NC_014833.1\|WP_013483496.1\|1320019_1320337_-\|IS66-family-insertion-sequence-hypothetical-protein	gnl\|CDD\|274987	TIGR04111, conserved_hypothetical_protein, phage-associated protein, BcepMu gp16 family. Members of this protein family occur in Burkholderia phage BcepMu, Pseudomonas phage B3, and Burkholderia phage KS10, and many bacterial putative prophage regions. The member from Burkholderia phage BcepMu is named gp16. Homology suggests DNA-binding activity. [Mobile and extrachromosomal element functions, Prophage functions].	0.000537696
NC_014833.1\|WP_013497844.1\|1331463_1333041_-\|RICIN-domain-containing-protein	gnl\|CDD\|379501	pfam14200, RicinB_lectin_2, Ricin-type beta-trefoil lectin domain-like.	4.7597e-19
NC_014833.1\|WP_013483393.1\|1319669_1320026_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	9.05932e-54
NC_014833.1\|WP_013497843.1\|1329130_1330702_+\|AAA-family-ATPase	gnl\|CDD\|313108	pfam09820, AAA-ATPase_like, Predicted AAA-ATPase. This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.	2.62053e-25

>NC_014833.1|WP_013497841.1|1323580_1325143_-|hypothetical-protein
MNKRIISIILSCSILLQNSQLAVFAQEESSSLPNDNYTVDISDNVDITSIVIANRMTGADVRAQRKFTAAQGHGFAAERGNNLIDKIKGSNAIVIGDNNVKNGADRIIIQKTGENIFIQDKYYQSAPASINACFDEEEIFRYFDSDGKPMQIEVPKDQYDNAVDLMKEKIKNGSVPGITDPEEAERIVRKGNLTYKQAVNIAKAGNIDSLKYDATNGIVSSSAAFGIDTLLNFAVRVNSGEEYSDAIKDSAIDGLKAGGMQFATAVIAGQLAKTNVKNVFRPSATALVDALGDDFAKTLTKTMEKELIEEGAESLGKTAAKKAAVELISSNALVDTVSLIVFTVPDGVKLFNGKISKKQFIKNFAVAGVSTVAGAAGGYAGGIIGSLVVPGVGTLPGAIIGSVLIGGGASIAADAIADYITDDDADEMYEIIQNKFADKCEEYIVTESEATNIAKELSNKLDEDVFEKMYQSNDRSKFADDLLEPLFEKEVKKRPKVKVPTEDEMRASLLEELNGVVFLH
>NC_014833.1|WP_013497840.1|1323125_1323467_-|hypothetical-protein
MNLQDLDDILSAHTLVEKDKIMNYTFAVTGLSFLKIRDILIVKGNIIFEDLENKVYVAFIRSGFMKKSDAKAAIHLYNEQLLISIYAKEGIVNQRICEGAINELEKSLKDYIG
>NC_014833.1|WP_013497839.1|1322089_1323034_-|hypothetical-protein
MNKELATFEKDYLSYCDIYDNAVKKYNTNADKINNFIADVDRFNVFSEVHNIEHRSEINRNFDEYRKSNDDISVISNDVKKINTETKKLEESYLPICETAYDTIVNNYNDLVNDYNSLKEKTSLDFIKDIPEYKTINDSELYVLDETSFTEEKLIDEISKISDNINDISQLYIVSEQITAPSKDFIYERLKDVESITSTKAVTTYYDPNKLLGEEGGYTSCVYFTVDNIAVSDVNGIDAAHKGVDGGGSVEVYATLDDALKRCDYLSQFDGTLLYSGSYTIVGTMVIRTSYKLSNEEQIQLTDDIINSLTEIKE
>NC_014833.1|WP_028504470.1|1320589_1321453_-|SUKH-3-domain-containing-protein
MKGSEMSIIIDDQYRHSPRYEKHFNVFCEGLEKHFNDIPVFDAAMQFYKEYHFIRYLSDHNGVTCGSFEYDDTNLHLNGIRLEEAVRKLVKDNGIKYLPAAVVYLKKAFFRFILINENGEFYLDDGTYLGTDYEKIVESILNGEKEIVPILNDRIYTSLERHGWDPDKIIDTAPIEEKYRELGFSFFPAANKFFEVIPIGKYRIWIPKSDDDCYVGFYPNKRMKDPKEFQNEIGEDLLTIAAKREANFFISESGKFYAQYEFTREMFYVTDDLYLFIYYLLINRNGF
>NC_014833.1|WP_013483496.1|1320019_1320337_-|IS66-family-insertion-sequence-hypothetical-protein
MDKTTSITTIKKEMQLQEWSAQIKAQQASGLTIREWCKEKGIKPNTYYNRLRKVREKYIENSPTIVPVSVPCSNENIRIEKNGLQISLPADISADTLTALVHELC
>NC_014833.1|WP_013483393.1|1319669_1320026_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNDLAADAQVYLVTGYTDLRRGIDGLATIVQAQLRLDPFSKALFLFCGRRCDRIKGLLWEGDGFLLLYKRLDNGRFQWPRSETEAVMLTSQQIRWLLEGLKIEQPKAIREGKPGALY
>NC_014833.1|WP_013483805.1|1318065_1319577_-|IS66-family-transposase
MSEPNMTSEIVSLRNENAVLKEELALANQQLAWFRKQIFGRKTEQTSVVMEKEFGVQLSMFGNNEEKSAAKSAETITVPEHKRKKKRTHDEWMNNLPVKEEHHKIDNPVCEICGAEMEELTPEKAYDELIFTPPKYHIRRHIVHKYKCPECGEKPEERDEPCHIIRAPYPHAMIPGSYCSPELLAHIIYEKYAKSVPLHRQEKDFNSKNIPLLKATMSNWVGTAAEKWCLPIVEKMHEMLIAGQMIHADETTVQVLHEEGRKPTTTSRMWVYCNGKMNDRSIIIFDYQPTRKGEHASNFLKGFIGYLICDGYDAYNAVEGAKRCGCMTHARRGFIQALPNDQKLHSTSVAAKAVEYFNKIYHEENLLADSSTEYRYKQRLVKVKPLLDEFFAWLENVQVSGKGKLTDAVRYALNERKYLYTFLENGDVPIDNNRAENAIRPFALGRKNWLFSNTANGARSSATLYSIISTAQANGVDAEKYLTELFSQPAGTILLPWREENET
>NC_014833.1|WP_157865473.1|1317537_1318014_-|hypothetical-protein
MNREYHILPEEDYFGQGMIDPQDAAEVAHFLWERTWIIDDYLERSDLPEEHMEILKSWKGCITGRFIIERHWKKGSVFISIDDNSVFLVNGIVSSWEEMLRNAPMPTLLDAALLPFKNAIISDGLVSVMPIIFGPNSKADFKEIYMDAKRNGEIKARI
>NC_014833.1|WP_013497837.1|1312754_1313045_+|CRISPR-associated-endonuclease-Cas2
MLVLITYDVSTADNAGKKRLRRVAKQCVNYGVRVQNSVFECELDPAQCRLLKQKLTEEIDETKDSLRFYYLGNIKKAKVEHVGSKQTLKVDEPLIF
>NC_014833.1|WP_013497836.1|1311718_1312750_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLLNTLYITSPDRYLSLDGENVVVQADGKEIGRVPLHNLERIMTFGYTGASPALMGKCAANGIELIFMSGSGKFLARVEGEVNGNVLLRRQQYRYADESKVSLDISKNIICAKLFNSRWTIERTLRDHPMRIDADKFDNCSQQLKKSIDNARKADDIDTLRGIEGEAAQIYFSVFDDMILQQKDDFSFKTRNKRPPKDTVNALLSFAYSLATSMCTSALEAVGLDPYVGFMHTDRPGRRSLALDLVEEMRSPLCDRFVLTVINKKIISAHDLEKREDGAVILTDNGRRAFITAWQKRKDDELKHPFLDEKIEWGTVPYAQALLLARYIRGDLDAYPPFMWK
>NC_014833.1|WP_013483393.1|1326433_1326790_+|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MLNDLAADAQVYLVTGYTDLRRGIDGLATIVQAQLRLDPFSKALFLFCGRRCDRIKGLLWEGDGFLLLYKRLDNGRFQWPRSETEAVMLTSQQIRWLLEGLKIEQPKAIREGKPGALY
>NC_014833.1|WP_043550584.1|1328738_1328921_+|hypothetical-protein
MLRNAPMPTLLDAALLPFKNAIISDGLVSVMPIIFGPNSKADFKEIYMDAKRNGEIKARI
>NC_014833.1|WP_013497843.1|1329130_1330702_+|AAA-family-ATPase
MGMLLNPSAESYRMAVNSKIYIDKSMLISVMNECINTSQRFVCVSRPRRFGKSITADMLCAYYGQEDTDSLFRTLKISGSPDYKKYLNKFQVIHLNMINFMDKHDSLEGSLDYLQKRLLHELKSQFSGVDCFDWNDLPSVLEDIYNAVHVKFVFVIDEWDCIFRRNKNDTENQTLYLDFLRSLLKDKVYVALAYMTGILPIKKYGEHSALNMFKEISVADAGVYAEYTGFTEEEVRELCGKYEMDFDEVKRWYDGYNVNDVSIYNPKSVVEAMLSKELGNYWTQTETYEALKEYIQANFDGLRDKVVQLIADEPVKVNILKFQNDMTNFSSADDVLTLLIHLGYLTYNKADRSCYIPNEEVRQEFINCIEDGGWENVMSAIRSSERLLEDTLKGNEKAVSDALRELHYQNTSLLTYNNENSLSCLLSLAFYSAKKYYTIFRELETGEGFADLVFIPLKHSDKPAMLVELKYDRSADTAIRQIKEKRYHGALTEYLDKLIIVGINYDKNTKEHTCRIERFNAEK
>NC_014833.1|WP_013497844.1|1331463_1333041_-|RICIN-domain-containing-protein
MSRFSIAKKLTSAVAAVGIAVSALTTAVPLNAFAASNYISDGWYYIKNVNSQKYLDVSGKKDADGSNVIQYKGNGGNNQKWYVTNLGNNVITIRSGLKGGRMLDVENGANTDGANIRLWSANGANAQKFKVVKSSSGVYCLKTENSGESKAVDVYGWSTSDNGNINQWTYNGLACQQFKFESTSAGASKSSGSSSSSSSSSSSSSSSSSGSSSSSSGSSSSSGSSLEVKNGGTSLSSALSKAKKGDTVVINGTVKSGAVKVPAGVNISGKNSAVIDFSSTSGGNGRGLTFEGNGSTVQNVCIKNASDNGLYITGSNNTFKNVEACYNKDAGFQVCNGGSNNKFYSCHSHHNADAKGENADGFANKLHSGTGNYYENCIADYNSDDGWDCYAAHGAVTLVNCQANYNGYCDGIYGDGNGFKMGGVDNKTSGEKAHLDPLNHVLKGCTAKGNYASGFDRNNQNGVVTMENCTGDSNKKYNFNWPASGTPSALGYKVTFGVAKIISCTSKNGKNNIGGAKLSGNCSGF
>NC_014833.1|WP_013497845.1|1333693_1333852_+|hypothetical-protein
MNRHIIIRAVLAAIWVIVGIVVLIKGQMTSGLISLAMGAAFGFSAFSMSRKK
>NC_014833.1|WP_013497846.1|1333861_1334581_+|ABC-transporter-ATP-binding-protein
MADLLQLAELKAWYDPEKQVLKGLDLILEEHSVIGLIGLNGAGKTTLMNVLCGLHTGFSSNELKFSGKNFSFKDKEFKEQRYIVFSEDESFGYFSFDEYIAYVFGCYNKKPDKTYIDELVEKFGFGDYRSTFIKDLSLGNRRKVYLITGFALKLPLLLLDEPVNGLDFNSTEALYDLIAGYKKFGTVLFSSHILESVTLTSDKVLVLENGIIARTYSGSDITTENIRDSLEKASVVKDV
>NC_014833.1|WP_037304971.1|1334582_1335713_+|hypothetical-protein
MLSRKLLGEKYRSSLQNVLISVFVAYGLYSLDKQIPLSKKVLVLTIIVYSGTLIIQALGSADNAKVLHGLFAMPCNERRTLGEYTLVIGLYVLTSKVSLLAALLFAFTKMTVYSCALLLLAFLLALFGGMATFGHFKKRPYISVLYVAAGIAMAFFLPDGKAAVIALTAADVIFGGTLFFLRMEDFRVCPTAGRRRKTVAAKKPTFLILRYLWRYMLEKKAYIFSTLFIIGFAVFFSRNAENMGLKIACGMGMAAISINSPVSTMVSANRGLDRKLDALPSKTERFFIPFGGVLFCFYLLCFGLFLTAFHVAGGNVGIRYLVLAPVFAAEGALFTSFLENRYPIKNWKTEADLTHNPRKYILPIALMAEAAIVGFI
>NC_014833.1|WP_013497848.1|1336400_1340327_-|fibronectin-type-III-domain-containing-protein
MKCRIRNIITTASAVALTVAAVPAATTYAASVDDAQAAISENVGEAAAVTRLAVASETTTWNKPVSLTEDTVVDGNLIVSADVDLNGFSLTVNGNLDHSEGAIICNSGSLNVNGTYSIGNIMNYTSPDLILSNDRDEVNINGDLVTYLIKENHGILQDAGIVTVSGNISADSGFIMNTDTYTTLVLNGTSDQNVYFGNCPTLNVLKVIDPEMREIIWHGDMNVRNLDSDIHVQSNDLNLGDINLANYSMVVNGDCSIAKSNFVDINGGSLTIYGNLDHSEGAIICNSGSLNVNGTYSIGNTMNYTSPDLILSYDCDEVNINGDLVTYLINENHGILQDAGIVTVSGNISADSGFIMNTDTYTTLVLNGTSDQNVYFGNCPTLNVLKVIDPEMREIIWHGDMNVRNLDSDIHVQSNSLNLGDINLAYYSMVVNGDCSIAKSNFVDINGGSLTIYGNLDHSEGAIICNSGSLNVNGTYSIGNIMNYTSPDLILSNDRDEVNINGDLVTYLIKENHGILQDAGIVTVSGNISADSGFIMNTDTYTTLVLNGTSDQNVYFGNCPTLNVLKVIDPEMREIIWHGDMNVRNLDSDIHVQSNDLNLGDINLANYSMVVNGDCSIAKSNFVDINGGSLTIYGNLDHSEGAIICNSGSLNVNGTYSIGNTMNYTSPDLILSYDCDEVNINGDLVTYLINENHGILQDAGIVTVSGNISADSGFIMNTDTYTTLVLNGTSDQNVYFGNCPTLNVLKVIDPEMREIIWHGDMNVRNLDSDIHVQSNGLNLGDINLAYYSMVVNGDCSIAKSNFVDINGGSLTIYGNLDHSEGAIICNSGSLNVNGTYSIGNIMNYTSPDLILSNDCDEVNINGDLVTYLIKENHGILQDAGIVTVSGNISADSGFIMNTDTYTTLVLNGTSDQNVYFGNCPTLNVLKVIDPEMREIIWHGDMNVRNLDSDIHVQSNDLNLGDINLANYSMVVNGDCSIAKSNFVDINGGSLTIYGNLDHSEGAIICNSGSLNVNGTYSIGNTMNYTSPDLILSYDSDEVNINGDLVTYLIKESHGILQDAGIVTVSGNISADSGFIVNTDNNTVLNLNGMSKQNINLPTGTKINILVINKLLSCYEFNQKECWNKLVTDYPAYYPAVVIKKWEKGDRAVRLKWDAVPGAEKYAVVGYVNKKWTVLDYGYNTTYVLSKLKPGENYKVAVVAKIGGKWSRDVSKAIVVTPKNVNKYPVVTAEVSGKQFRLNWTPVDAAEEYAIAVFQSGKWVVKAKLDSNTTTYTSPKIKSGTYTLAVCAKVNGKWDKSDLNSRAVTVTIK
>NC_014833.1|WP_013497849.1|1340701_1342483_+|DUF4832-domain-containing-protein
MKNTNIRSSLIKRLAASGISLCLAVSVLQTEADAAGMKTVDEISYKETLEDTHNPYRGFYQAFVVSYKRNKSNCKAQASTLEELDELASEYHLIHLLIDLSDFSAQNRKGQNAVKHSADANIDPSNDDVEEALGQLLERLRNNGQSAVIRFAYDYKYSGITSDGTDENGDPSYRTVWEPTDDSIIEQHQEKVGAVISKYTDVIASVECGIIGPWGEMHTSERTDSESEKKIIGKWLEVLPDDMTVNVRKPSDFCAWSGIELENIDKYTAGKGTDAYRIGMYNDGYLGSVSDLGTYDDRKKEIAWLKTQTDHTLFGGELVQWDNEEGGTPLNNIAFFEKEGFKTHTSYLNKDWHDDVMDGFRSTTYNGGDPFYKGKTTEFEYLRNRMGYRFVVRNVRMTTGISPYENFELETAIENVGFGNLIKNEQTSVIIKGNGLEKEFKLWELDEGKGEKASNYAPQKWLSGSSLTERKTNIMSAELDLPNDMPVGNYKVYIKIANRKNGEGEYPIRFSNAGSNVYDSKLKANFVGSLKISKPYKGDVNNDGKLNGYDLLLLKQRILNLVSDKELDMKNADVNRDGRVNIMDYVELYKICR
>NC_014833.1|WP_013497850.1|1342743_1343838_+|leucine-rich-repeat-domain-containing-protein
MKSKKIISGLLALSFVFGGTALPNTVVNNSVSASASVEEIAEEAEVLTYGDYKYKLLDDGTAEIVEYTGDCTEIEENGTEEIEIPSELNGAIVTSIGYHAFFCHMELGSITLPKDLKNIGDGAFKDCNGLSSIVIPDGVECIGDDAFRSCRVLSSVTFSKNLKYIGKEAFRYCSCLHDIVIPDGVEYIGERAFAKFDSSSDNDIGYYLHYSVTIPKSVTFIGDNAFNNFSIASYAFKPAKDYIINCYKDSAAHNYALVNGNNFNVIDAGDSKTKYPELIKEEYSPKFHKFRLNWTAVEGAEQYGIAVRLAGKWKVQAYVDADTTKYVTPKLTSGQNYQTVICAKVNGKWDTSVLNNRAFPLVVR

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Crispr_ID: NC_014833_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_7

2788118-2788250

Orphan

Consensus_repeat	Method
TATCAGCTTTAGAATTGCTCTCTGTTGTATTGTACGGCATTGTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014833_7

>merge|NC_014833|7|2788118-2788250|CRISPRCasFinder
TATCAGCTTTAGAATTGCTCTCTGTTGTATTGTACGGCATTGTAAAGCCTGCTGTTGTATTTGTCGTATCTCTATACTACCTTACCATGTATCAACTTTAGAATTGCTCTCTGTTGTATTGTACGGCATTGTA

>NC_014833|7|7|2788118-2788250|CRISPRCasFinder
TATCAGCTTTAGAATTGCTCTCTGTTGTATTGTACGGCATTGTA	AAGCCTGCTGTTGTATTTGTCGTATCTCTATACTACCTTACCATG
TATCAACTTTAGAATTGCTCTCTGTTGTATTGTACGGCATTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_013499081.1\|2785219_2785972_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_014833.1\|WP_013499079.1\|2783912_2784791_-\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|376546
NC_014833.1\|WP_013499075.1\|2778675_2780379_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375901
NC_014833.1\|WP_013499080.1\|2784815_2785190_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013499082.1\|2785968_2786277_-\|TrpR-like-protein,-YerC/YecD	unknown	unknown	gnl\|CDD\|226893
NC_014833.1\|WP_013499086.1\|2790231_2790978_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NC_014833.1\|WP_013499094.1\|2797046_2798012_-\|DUF2628-domain-containing-protein	unknown	unknown	gnl\|CDD\|373073
NC_014833.1\|WP_013499089.1\|2792539_2792935_-\|cytidine-deaminase	unknown	unknown	gnl\|CDD\|223372
NC_014833.1\|WP_013499093.1\|2796627_2796918_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|275385
NC_014833.1\|WP_013499092.1\|2795952_2796555_-\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|366099
NC_014833.1\|WP_013499083.1\|2786545_2787733_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_014833.1\|WP_013499091.1\|2795652_2795898_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
NC_014833.1\|WP_013499078.1\|2782805_2783183_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319940
NC_014833.1\|WP_013499076.1\|2780430_2782275_+\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NC_014833.1\|WP_013499090.1\|2793004_2795431_-\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NC_014833.1\|WP_013499087.1\|2791154_2791580_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013499085.1\|2788492_2789563_-\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013499074.1\|2776631_2777981_-\|NADP-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|181834
NC_014833.1\|WP_013499077.1\|2782279_2782690_+\|peptide-deformylase	unknown	unknown	gnl\|CDD\|181704
NC_014833.1\|WP_050793287.1\|2791746_2792454_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_013499081.1\|2785219_2785972_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.66131e-17
NC_014833.1\|WP_013499079.1\|2783912_2784791_-\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|376546	pfam01430, HSP33, Hsp33 protein. Hsp33 is a molecular chaperone, distinguished from all other known chaperones by its mode of functional regulation. Its activity is redox regulated. Hsp33 is a cytoplasmically localized protein with highly reactive cysteines that respond quickly to changes in the redox environment. Oxidising conditions like H2O2 cause disulfide bonds to form in Hsp33, a process that leads to the activation of its chaperone function.	1.00392e-119
NC_014833.1\|WP_050793287.1\|2791746_2792454_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	3.07689e-94
NC_014833.1\|WP_013499094.1\|2797046_2798012_-\|DUF2628-domain-containing-protein	gnl\|CDD\|373073	pfam14446, Prok-RING_1, Prokaryotic RING finger family 1. RING finger family found sporadically in bacteria and archaea, and associated in gene neighborhoods with other components of the ubiquitin-based signaling and degradation system, including ubiquitin, the E1 and E2 proteins and the JAB-like metallopeptidase. The bacterial versions contain transmembrane helices.	1.00516e-26
NC_014833.1\|WP_013499082.1\|2785968_2786277_-\|TrpR-like-protein,-YerC/YecD	gnl\|CDD\|226893	COG4496, COG4496, Uncharacterized protein conserved in bacteria [Function unknown].	7.66246e-40
NC_014833.1\|WP_013499086.1\|2790231_2790978_-\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	8.07901e-26
NC_014833.1\|WP_013499089.1\|2792539_2792935_-\|cytidine-deaminase	gnl\|CDD\|223372	COG0295, Cdd, Cytidine deaminase [Nucleotide transport and metabolism].	7.21887e-26
NC_014833.1\|WP_013499093.1\|2796627_2796918_-\|30S-ribosomal-protein-S6	gnl\|CDD\|275385	cd00473, bS6, Bacterial ribosomal protein S6. bS6 is one of the components of the small subunit of the prokaryotic ribosome, a ribonucleoprotein organelle that decodes the genetic information in messenger RNA and forms peptide bonds to synthesize the corresponding polypeptides. Ribosomes consist of a large and a small subunit, which assemble during the initiation stage of protein synthesis. Prokaryotic ribosomes consist of three molecules of RNA and more than 50 proteins. The small subunits of bacterial and eukaryotic ribosomes have the same overall shapes (with structural elements described as head, body, platform, beak and shoulder). The bacterial ribosomal protein S6 is important for the assembly of the central domain of the small subunit via heterodimerization with ribosomal protein S18.	1.01398e-29
NC_014833.1\|WP_013499092.1\|2795952_2796555_-\|single-stranded-DNA-binding-protein	gnl\|CDD\|366099	pfam00436, SSB, Single-strand binding protein family. This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.	2.10227e-34
NC_014833.1\|WP_013499083.1\|2786545_2787733_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	4.1241e-09
NC_014833.1\|WP_013499078.1\|2782805_2783183_-\|VOC-family-protein	gnl\|CDD\|319940	cd08352, VOC_Bs_YwkD_like, vicinal oxygen chelate (VOC) family protein Bacillus subtilis YwkD and similar proteins. uncharacterized subfamily of vicinal oxygen chelate (VOC) family contains Bacillus subtilis YwkD and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	9.43639e-11
NC_014833.1\|WP_013499076.1\|2780430_2782275_+\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NC_014833.1\|WP_013499091.1\|2795652_2795898_-\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	3.1453e-35
NC_014833.1\|WP_013499090.1\|2793004_2795431_-\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NC_014833.1\|WP_013499074.1\|2776631_2777981_-\|NADP-specific-glutamate-dehydrogenase	gnl\|CDD\|181834	PRK09414, PRK09414, NADP-specific glutamate dehydrogenase.	0
NC_014833.1\|WP_013499077.1\|2782279_2782690_+\|peptide-deformylase	gnl\|CDD\|181704	PRK09218, PRK09218, peptide deformylase; Validated.	1.49302e-82
NC_014833.1\|WP_013499075.1\|2778675_2780379_+\|hypothetical-protein	gnl\|CDD\|375901	pfam18475, PIN7, PIN domain. This is a bacterial PIN-like domain of unknown function.	6.11158e-36

>NC_014833.1|WP_013499083.1|2786545_2787733_-|site-specific-integrase
MAKKKSNTNCFYVGDRQFNAHIADNGNYYIQADFGKDESGKRIRKKVTAKSLNELSKKVEELIIELESNHGDNITLVNAFESYINTHASLAYNTLNSYRNTIKYYFKELQNKPIRQITKSDLMQAINTDIAKGCAKTTMKREFTVLCVVLNYFEVPALTPKVQKELKSYVNNATYIGKGRKKDFENLPTALDVVEWLKADTTKYKDRTAVCVLLGLHSLRVEEVRGLKFKDVIKEKNGNCYVNIHATKTCIRGKDHFREETKNEYSTRRFLIDNRLYDMIHSIEHKSDDDFVISICNWQYGSCIKQLAIKNGYDWITAHILRHIFISDNKDCTIAEIVGGWSLKGGVSKTVYTHARHEEKEKLTKEYSGKLLDCYFDTEKDSCERNITWTVNKAV
>NC_014833.1|WP_013499082.1|2785968_2786277_-|TrpR-like-protein,-YerC/YecD
MRDKLEIANLDELYEAILCLETLDECRLFFKDLCTVPELKSFSQRFQVARMLTDKHVYSDIVKETGASTATISRVNRSLSYDGSGGYNIVFDRLEKKKGSEE
>NC_014833.1|WP_013499081.1|2785219_2785972_-|class-I-SAM-dependent-methyltransferase
MNGYSSFAGYYDALQKDVPYGAIAARIRQLGLEYSSENEVVVELGCGTGRLCRELEKFGLDVIGVDISADMLEEAEEQRTPDSDITYICQDMSELDLWGAADMIVCVLDGMNHLPNEEAFRRTVERASMFTCDGGLFIFDVNTEYKHREVLGDNCFVYELDGLFCAWRNNCRADGRVDIALDFFAEKEDGSYTRESEYISEILLPRDLIEETAEEYDFEQIGVYDGLTNDPPCDTTQRELYVFRRKPRGL
>NC_014833.1|WP_013499080.1|2784815_2785190_-|hypothetical-protein
MEDKYTDFEEYDISDLELIINEQRDLYSEEEIERAKELLERKKHEEISNRNTTADLSIKDVDRMFTMLCICALLSPLCGIVSCVGVGIKCSARLRRYMKTLIAATIVSLILRVFLAYGGIMPFI
>NC_014833.1|WP_013499079.1|2783912_2784791_-|Hsp33-family-molecular-chaperone-HslO
MGRIVRAISKDASVVCSAIDGKDIVEEIERVHESSAVVTAALGRLAMGTSLMGFGMKGEDDKITVKIEGGGPAGQLIAVADSYGNVKADVMQPVVELPPNAIGKLDVAGAVGTDGTITVIKDLGLKEPYVGQVPLISGEIAEDITAYLAQSEQVPSVCALGVLVNADLTVKNAGGFLIQVLPFASDEIITQIEKNIQAMQSVTKLMEDGRTTDEIALMALEGLEPNVLDDFKVEYRCDCSRERTERVLISLGEAELNDIIKDGNVDIKCHFCGKEYTFTPDEVRKLIAESKE
>NC_014833.1|WP_013499078.1|2782805_2783183_-|VOC-family-protein
MIKGIHHISLKCHGGDELEKVRELYSGILGLEVKREWCDGVMFDAGNCLIEVFTNGEGIKTTGAVRHFAFAVDDVDTIIESVREAGYEVFKEPSDICIPSEPPLPARMAFFYGALGEEIELFCEK
>NC_014833.1|WP_013499077.1|2782279_2782690_+|peptide-deformylase
MVREIVHDVIFLKKKSIKADKNDVDIITDLRDTLKANHDRCVGMAANMIGFNKRIIIFTAGIMDIVMINPVIVKKAQPYETEEGCLSLTGVRKTKRWEKITVEYQDTSFNKKRGDFTGFVAQIIQHECDHLEGIII
>NC_014833.1|WP_013499076.1|2780430_2782275_+|excinuclease-ABC-subunit-UvrC
MHITEEHNPRLPYLRDKTSKLTTSPGVYIMKDKSGKIIYIGKAKNLHNRVNSYFRKGQDHLPKVWKMVSNVNDYEFIVTDSEFEALVLECSLIKMHTPKYNILLKDDKGYSYIRVTDEPYPRIQAVLQKSDDSAEYIGPYTSSFTVKQAVEEANRVFRLPTCTKIFPRDIKKQRPCLNYHIKRCMGVCTGEFSEEEYRSIVSQAVDYIKNGSSSSVERLTEEMERAAENLEFELAARLRDRITAIQKAAESQKVIDETIPDCDIIAISQSADIACASVIMYRGGRLTDKADYFLGDRSEPAAMMEEFVLSFYAMKDDAPKTIILEEDPTDILMLEQYLREKYDHAVHVSVPKRGHLLRLSTMAKNNANAFISVRVGRTGREVAGLDELARALGMEKPPRFIECYDISNLASTDMVAGMVVFENGRPCRKNYRKFSIKTVFEQNDYACMTEVIERRFAEYKKGTDDGFAQLPDLILLDGGNGHVNTIRPVLERLGISVPLYGLVKDDRHRTRAIATGSGEISLLKSRAAFALVTQIQDEVHRVAISYQRSKRRKTAFSLELTSVRGVGEKKAQKLMREFKTKEALKKASAEELRAVAGISADTAAELKKIIDEMS
>NC_014833.1|WP_013499075.1|2778675_2780379_+|hypothetical-protein
MKIYLIDFENVKSKGLTGIDSLTEYDRVIIFYSENADTINFEMHQKVLISKAEVEYFKVHVGGKNALDFQLSTLLGYLVSKNYYSHIFVISNDKSFDFLHDFWHGKYIAAPDCIVYRTKTIAQAINYAGGKKQIVPDDDDTDTAVFGAADDTSAENSAEDITKDIQAAEEVNDTKSEAAETDTAQPAPNNEAAEKPPVMSADLTEKRSPKPAPKKEKAPVQAKRTQPDKAEEFTISAEELNALEASFSAYSIIDVKKNDKKTESKTENIPEKKTADIPVEKPSAVPAAKKEAAAVCEPAKAEPPTKEAVSEKPADKPKAKSNGFFAALKEIMKKTDCKAEMINHISQLLINSDTKEEFHNALAKDYKQDATELYKLLRPKYLRLREMYAAEHPGFVTAPTADTAPVKAETTVKTEAPAKPASEPKADISVPETEKPAEQTSEKAEAPAAAEEKPAKKKTRSTKAKTAKAARSEEDKKPAKTAKPRTKKKAASDTASPDVNTQTKSLDQLLDGKCSPEEIELIRQLFREVPSRQQLYIRMIKLFGKKEGCVYYNAIKAEYETLREAIK
>NC_014833.1|WP_013499074.1|2776631_2777981_-|NADP-specific-glutamate-dehydrogenase
MALKNEYLQKVYEQVEKRNPGEKEFHQAVYEVLESLVPVADKRQDLIDAGVFDRIVEPERQIMFRVPWVDDNGKVQVNRGFRIQFNSAIGPYKGGLRFHPTVCASVIKFLGFEQTFKNSLTSLPMGGGKGGSDFDPQGKSDAEVMRFCQSFMTELCKHVGADTDVPAGDIGVGGREIGYLFGQYKRIRNEFVGVLTGKGMEYGGSLIRPEATGYGAVYYAVEMLKHYNDSIEGKTFAVSGFGNVAWGTIKKVNELGGKVVTISGPDGYIYDKDGITGEKVDYLLEMRASCRNRVQDYADKFGVPFYAGKKPWEAKADIYMPCATQNEVNLDDAKNIVANGAKYYIEVANMPTTADAVAYLKENGLNVAPSKAVNAGGVSVSGLEMSQNSMRYNWTAEEVDAKLHQIMKNIFDASVKAAKEYGLGDDLIAGANIAGFLKVAEAMKAQGVV
>NC_014833.1|WP_013499085.1|2788492_2789563_-|hypothetical-protein
MLYGKEINEIRKLRKNNRSNFRLRMIEYQFAQGHISREQELDKAVKLVLDYIGEKVKSPDTLKILSESEMYAGIDTIQIKTDKEIEEEVIKQKDYVHNNKRKCLKDGRWLYVVNPDKFNDNIGIYKKSEYTKVFDEMMFNLELTARELSLSRVDFRFDFFDDNTFNKLWKLNNVLIALLSQKYNIKNRYASTDIISCERLTLRAQTQYFQIEYYHKRKQEPNGNVDTRLELRSCKMANNTDERKEFEKWKTKLLKILDSDLYKTLQEEKNNRLYERWKKEKTTYKNMSVYEFLSKYIDHFYTQEQLSDFFKWLGYKAPNTAASDYKRKKGFEPISMKLLTEYVNKIISSGERFFDS
>NC_014833.1|WP_013499086.1|2790231_2790978_-|recombinase-family-protein
MKENNKVYGYCRISTAKQSIDRQITNIKRAYPTADIKAEVYTGTKSNRPEWIKLLKIVHAGDTIVFDSVSRMSRNAEEGFNTYMELYNKGINLVFLKEQTINTDSFKSVLGENKLSIKVNTNDDDTDRLINGIMSEVAIYITKLAEKQIRLAFEQSEKEVQDLHGRTSEGIREAKAKGKKIGRQNGQTVTTKKSIAVKEMIVKYHKAFGNGTLNDIDTIAMINGQGVGVARNSYYKYKSELFAEYGIE
>NC_014833.1|WP_013499087.1|2791154_2791580_-|hypothetical-protein
MNNVNSIEEVKEIFKLADPAFDFRKDDSWDLTDMDRLKRGVGAELVIDIGKSDGEDSFISWLTSRVINPIVKVRETHLTIKTRMETILLLDWDSVIVKQIKTISDDCLDYTDYVVVLGADSKDYQLALRVNKELQKYCNYI
>NC_014833.1|WP_050793287.1|2791746_2792454_-|YihA-family-ribosome-biogenesis-GTP-binding-protein
MKPLNFNKAEFITSYGKLSQIPESDRPEFAFSGRSNVGKSSLINKIFNRKNMARVSSVPGKTVTINFFSVEDVYFVDLPGYGYANVSKGEKKGWGDLIGGYLADFDRDLELVFQLIDMRHAPSKDDIQMINYLIDNEIPFVIVLTKADKLKPTARKERMEAFKDEIPYFEDIHCIPFSAVTGEGVDELKAIIEEIREDWYTRTEDAEEEDISEEAPDYEDDSEPPAGFLTPNRNR
>NC_014833.1|WP_013499089.1|2792539_2792935_-|cytidine-deaminase
MEQIWKDMHDAAEAVIGARKISDYVTCGEVSAAVLSKSGKIYTGVCIDTCSTLGICAERNAIFNMITNGEQEIAKVLCISPNPSKGAPCGACRELMVQLMPEGYKDIEIMMDYEAGRIMTLGDLTPEWWIG
>NC_014833.1|WP_013499090.1|2793004_2795431_-|endopeptidase-La
MEKRTDIKNGTLMPMIPTRDLVVFPGMSVNFDVGREMSIQSLHNARNDFSGDVFLCAQKDINVESPEKKDMFRIGTIANIRQVIKSPGGVCRCMVRGVRKARLSEMIVHDDCYEAVIKPLPNYSKDKLYNHELEAVEREVRKAFEEYARLMPKMPQEIYTAVMGAKNAADLFEAVAFNIPLSFMDRQALLEAQSAGEKLVLMMTILAREIDVLSLEKEIHEQVQSQIEDNQREYYIREQIKALQNELGEGGFDGSDEGEIQKYYDKIEEMKAPDEVKEKLNDEVRRLSRMAGSSQEAVVIRGYLDTVIGLPWGVFTKDTADVKKAQAVLDKDHYGLKRVKERILENLAVRELTPDIKGQILCLVGPPGVGKTSVAKSVARALNRKFVRVSLGGVKDESDIRGHRKTYVGAMPGRIINAMKLAGSCNPVMLLDEIDKMSNDFRGDPSSAMLEVLDSEQNNAFRDHYTEIPYDLSNVLFITTANTLDTVAAPLLDRMEVIELSSYTREEKFNIAKKHLVKKQLEKHGLTSSMMKLTNDGIYQLIDGYTREAGVRTLERTIGSLCRKAAREIVENDVKKVAFSAKNIPDYLGHIKYLPDDAAKEDQIGCVNGLAWTAVGGVLMPLEVLVLDGKGKVELTGSLGDVMKESAKIAVSYCRSIADEYGIDKDFYEKKDMHIHAPEGAVPKDGPSAGVTMITAIVSALSGRKVRADVAMTGEITLTGKVLPIGGLREKTMAAFKAGVKTVIVPEKNRGDLDEIDDVVKDGLEFVFAERISDVLDAALVKPPENAVLPDMMGNPQPRVKARSRKTI
>NC_014833.1|WP_013499091.1|2795652_2795898_-|30S-ribosomal-protein-S18
MEKERTGGRPVKRGRKKVCMFCVDRAEKIDYKDIAKLRKCMTERAKILPRRVTGTCAYHQRELTKAIKRARHVALLPYVAD
>NC_014833.1|WP_013499092.1|2795952_2796555_-|single-stranded-DNA-binding-protein
MLNRVILMGRITQDLEVRQTPNGVSALTFNVAVDRNFKDQSGQYQSDFITCVAWRQTAEFIGKYFGKGRLIALEGTLRSRTYEDKNGTKHYVTEVYVENASFTGEKAQQGGGNYSQNYGNGGFNNGGYGNNGGYSNGGNGGFGGNNFNNGGNFGGGFGGNNGGNQNSFNNNNNQAPSNDALNIGDLSEFEDVLSDDGVPF
>NC_014833.1|WP_013499093.1|2796627_2796918_-|30S-ribosomal-protein-S6
MAKINENYEAMVIFSQKLDEEGVNALTTKFDDMIKANAENVELNVWGKRKLAYAINYETEGTYVLWSFNSKTEFPAELERVLGITDGVIRFLVTTK
>NC_014833.1|WP_013499094.1|2797046_2798012_-|DUF2628-domain-containing-protein
MANYTGSKCICCGKRFTDEDDIVVCPDCGTPYHRSCYVENGKCINSELHDKNIGWMPDAPAEEVTVTQASEVKRCIRCGAENDPSLRYCEQCGTPLVNMGAPRPFNDEADGTQKSDTDPMNTTIPGINITPVRLNQDSDIGGVKLGDLARYVGPNPLGFLPSFIKFGKTDRKLSVNFFAFLWPELYFMYRKMRKVGIIVAVLMAALNLPAMIEYLCSGEYGIKINFGINVKSEYFRMLQQAAYYIRVTLGILAGLFANYIYYRQAKKDITKIYHESEDEDRTVINYRIMNKGGISYADMLLGMMIYMMCLTGALVLLGKIL

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Crispr_ID: NC_014833_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014833_8

3541542-3541678

Orphan

Consensus_repeat	Method
CCGCATTCGTCCGATACCGTGTCACTAAAGGAGCGCCCTTTGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014833_8

>merge|NC_014833|8|3541542-3541678|CRISPRCasFinder
CCGCATTCGTCCGATACCGTGTCACTAAAGGAGCGCCCTTTGCTATGTATGTTGCGTACTGTGTACCCGCACGAGGGATGCGAACGCATATAGCCGCATTCGTCCGATACCGTGTCACCAAAGGAGCGCCCTTTGCT

>NC_014833|8|8|3541542-3541678|CRISPRCasFinder
CCGCATTCGTCCGATACCGTGTCACTAAAGGAGCGCCCTTTGCT	ATGTATGTTGCGTACTGTGTACCCGCACGAGGGATGCGAACGCATATAG
CCGCATTCGTCCGATACCGTGTCACCAAAGGAGCGCCCTTTGCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_014833.1\|WP_002847779.1\|3532945_3533377_+\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NC_014833.1\|WP_013499728.1\|3546184_3547429_-\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NC_014833.1\|WP_013499727.1\|3544810_3545878_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_014833.1\|WP_013499724.1\|3538865_3539105_-\|exported-copper-oxidase	unknown	unknown	unknown
NC_014833.1\|WP_013499719.1\|3533396_3534767_+\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl\|CDD\|236307
NC_014833.1\|WP_013499722.1\|3536543_3536777_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NC_014833.1\|WP_154662746.1\|3532493_3532913_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013499729.1\|3547482_3547929_-\|ACT-domain-containing-protein	unknown	unknown	gnl\|CDD\|179848
NC_014833.1\|WP_050793297.1\|3539126_3541427_-\|glycoside-hydrolase-family-95-protein	unknown	unknown	gnl\|CDD\|379625
NC_014833.1\|WP_013499730.1\|3548233_3548533_+\|hypothetical-protein	unknown	unknown	unknown
NC_014833.1\|WP_013499726.1\|3541832_3544790_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NC_014833.1\|WP_013499720.1\|3534766_3535660_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NC_014833.1\|WP_013499723.1\|3537068_3538808_-\|glycoside-hydrolase	unknown	unknown	gnl\|CDD\|366944
NC_014833.1\|WP_013499735.1\|3552387_3552981_+\|V-type-ATP-synthase-subunit-E	unknown	unknown	gnl\|CDD\|224308
NC_014833.1\|WP_013499733.1\|3551610_3552057_+\|ATPase	unknown	unknown	gnl\|CDD\|349413
NC_014833.1\|WP_013499732.1\|3549633_3551586_+\|ATPase	unknown	unknown	gnl\|CDD\|235600
NC_014833.1\|WP_013499721.1\|3535652_3536525_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NC_014833.1\|WP_013499731.1\|3548563_3549598_+\|V-type-ATPase-subunit	unknown	unknown	gnl\|CDD\|376708
NC_014833.1\|WP_013499717.1\|3531568_3532039_+\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	unknown	unknown	gnl\|CDD\|235777
NC_014833.1\|WP_013499734.1\|3552061_3552370_+\|V-type-ATP-synthase-subunit-F	unknown	unknown	gnl\|CDD\|376707

Protein	Function_ID	Function_description	E-value
NC_014833.1\|WP_002847779.1\|3532945_3533377_+\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	9.84691e-61
NC_014833.1\|WP_013499728.1\|3546184_3547429_-\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	1.17605e-148
NC_014833.1\|WP_013499727.1\|3544810_3545878_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	5.19554e-23
NC_014833.1\|WP_013499719.1\|3533396_3534767_+\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl\|CDD\|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
NC_014833.1\|WP_013499722.1\|3536543_3536777_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.29269e-25
NC_014833.1\|WP_013499731.1\|3548563_3549598_+\|V-type-ATPase-subunit	gnl\|CDD\|376708	pfam01992, vATP-synt_AC39, ATP synthase (C/AC39) subunit. This family includes the AC39 subunit from vacuolar ATP synthase, and the C subunit from archaebacterial ATP synthase. The family also includes subunit C from the Sodium transporting ATP synthase from Enterococcus hirae.	2.0116e-54
NC_014833.1\|WP_013499729.1\|3547482_3547929_-\|ACT-domain-containing-protein	gnl\|CDD\|179848	PRK04435, PRK04435, ACT domain-containing protein.	8.03569e-44
NC_014833.1\|WP_050793297.1\|3539126_3541427_-\|glycoside-hydrolase-family-95-protein	gnl\|CDD\|379625	pfam14498, Glyco_hyd_65N_2, Glycosyl hydrolase family 65, N-terminal domain. This domain represents a domain found to the N-terminus of the glycosyl hydrolase 65 family catalytic domain.	6.34548e-76
NC_014833.1\|WP_013499726.1\|3541832_3544790_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.12915e-06
NC_014833.1\|WP_013499720.1\|3534766_3535660_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	7.42799e-160
NC_014833.1\|WP_013499723.1\|3537068_3538808_-\|glycoside-hydrolase	gnl\|CDD\|366944	pfam02156, Glyco_hydro_26, Glycosyl hydrolase family 26.	2.9927e-39
NC_014833.1\|WP_013499735.1\|3552387_3552981_+\|V-type-ATP-synthase-subunit-E	gnl\|CDD\|224308	COG1390, NtpE, Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion].	6.09013e-15
NC_014833.1\|WP_013499733.1\|3551610_3552057_+\|ATPase	gnl\|CDD\|349413	cd18120, ATP-synt_Vo_Ao_c, Membrane-bound Vo/Ao complexes of V/A-type ATP synthases, subunit c. Vo/Ao-ATP synthase subunit c. The V- and A-type family of ATPases are composed of two linked multi-subunit complexes: the V1 and A1 complexes contain three copies each of the alpha and beta subunits that form the soluble catalytic core, which is involved in ATP synthesis/hydrolysis, and the Vo or Ao complex that forms the membrane-embedded proton pore. The A-ATP synthase (AoA1-ATPases) is exclusively found in archaea and functions like the F-ATP synthase. Structurally, however, the A-ATP synthase is more closely related to the V-ATP synthase (vacuolar VoV1-ATPase), which is a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. The V- and A-type synthases can function in both ATP synthesis and hydrolysis modes. The V1 complex consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The Vo complex consists of five different subunits: a, c, c', c'', and d. The Ao/A1 complexes are composed of nine subunits in a stoichiometry of A(3):B(3):C:D:E:F:H(2):a:c(x). ATP is synthesized on the A3:B3 hexamer and the energy released during that process is transferred to the Ao complex, which consists of the C-terminal segment of subunit a and subunit c.	4.1904e-15
NC_014833.1\|WP_013499732.1\|3549633_3551586_+\|ATPase	gnl\|CDD\|235600	PRK05771, PRK05771, V-type ATP synthase subunit I; Validated.	1.13328e-88
NC_014833.1\|WP_013499721.1\|3535652_3536525_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	1.65126e-152
NC_014833.1\|WP_013499717.1\|3531568_3532039_+\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	2.81468e-46
NC_014833.1\|WP_013499734.1\|3552061_3552370_+\|V-type-ATP-synthase-subunit-F	gnl\|CDD\|376707	pfam01990, ATP-synt_F, ATP synthase (F/14-kDa) subunit. This family includes 14-kDa subunit from vATPases, which is in the peripheral catalytic part of the complex. The family also includes archaebacterial ATP synthase subunit F.	1.64527e-20

>NC_014833.1|WP_050793297.1|3539126_3541427_-|glycoside-hydrolase-family-95-protein
MSSRQNGGVLMENKRIWFRRPAEDWNVALPVGNGRIGGMCFGQALNEKIQLNEDSVWSGGPRKRNNASARANLEKVRQLLREEKIAEAEKIVMEAFCGTPVNERHYMPLGDLSIQHHKEDTFEYTERSLDLENAVCETRYSINGVNYTRRVICSEPAQVMAVCIDADKPASVSVKVSIDGRDDYFDDNSPVNDTDILYYGGCGSEDGICFAAYIRVLGYGGTVGRWGSSIVTDCCDRVMIILGAQTDFRVTDYKKGAELDVITAAGKTFEELLAEHTEDYRSYFDRAEIVFEDGGSYSLPTDERLKLVKDGGVDNGLVSLYFDFGRYLMIAGSREGTLPLNLQGIWNKDMWPAWGCRFTVNINTEMNYWCAEPCGLGDLHIPLFDHIERMRPHGRDTAREMYGCSGFVCHHNTDIWGDTAPQDLWIPGTQWVTGAAWLCTHIWEHWLFTQDKEFLAQKYDTMKEAAKFFVDFLIDDGSGRLVTAPSVSPENTYITESGARGSVCIGPSMDSQIIYQLFTAVIEAGKILGIDKSFGEKLSAMRERLPKPEIGKYGQIKEWAVDYDEAEPGHRHISQLYALYPADMISIRHTPELAKAARATIDRRLAHGGGHTGWSRAWIINHWARLHDGEKVKENIAALFANSTSDNLFDMHPPFQIDGNFGAAAGIAEALLQSQNGEIQLLPAVSPDWKNGSFRGLRARGGYEIDCKWADSRPVKCVIKSPKGGRCRLVIPSGCEIKSSTVGYEVIGDCIEFDTGAVGFAEIAFA
>NC_014833.1|WP_013499724.1|3538865_3539105_-|exported-copper-oxidase
MEEKLRKRYGISMLVTNLISLIMLMCSRYSVDIPDTVRAVLITAGVFGAVIMIYTYVKMLKFRKDQKDLRDDTSQTGRV
>NC_014833.1|WP_013499723.1|3537068_3538808_-|glycoside-hydrolase
MKMRLLAAVTAAVLAAMCFGSCGKEIHDNKDISAKQELLTADEDTTEEETTEDEIVTPVPEEEVQEEVKSFKEVKVKAAELKYKKFDKTYQAEKGKLGGTAAEASKRKGYEGSGYVSGISQESDWELEFEVPASQFYNIVLTVGSDEAAAGGFSLNGSKYSEFTVINEDNEGRFENISFNNVKLKKGKNKIAFIPDTGIVDIDMVKVTASDEISKLRLKATGAVLSDKNAEYNAKALYRLLCNNYGIRVLLAQNDTAGTNYESELIHTVTGKYPAIRLGDMIYATGKEHADQCAAETAEALTWHKDGGIVGYMWSWTSPGKPDDGESIYAENADIDITKAVTGEDIALLDPDTLAAMAKDGTISKECLKLIGDIDKVSAQLIKLRDEGVPVLWRPLQEASNGLYWWGRDADSYIWLWQTMYDRMTSYHGLHNLVWVWSAQNINWFVGAEYCDVLSADVYGGGKSGQVNALLYLDSIAGGKPIAMSECDSMPLIQNIADERAMWSYIGQWGGSCIVGEDGGLSEKFNSEKDLITMYNNELTITRDKLPDLMTMATEIKKEEEKASKENTKKAKAKDKSED
>NC_014833.1|WP_013499722.1|3536543_3536777_+|acyl-carrier-protein
MVFDKIREIIVEQLDVDEDKVTTDASITEDLGADSLDVVDLVMNIEESFDLEIPDEEVENIKTVGDIVKFIEAKTEE
>NC_014833.1|WP_013499721.1|3535652_3536525_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MSEQLSASRRLDIIRHKGRPTALDYIPMIFDEFFEMHGDRLCGDDRAIIGGVASFEGTPVTVIAEVKGRDLEENQECNFGMPHPEGYRKALRLARQAEKFHRPVICLVDTPGAYPGVEAEKRGQGEAIARNIMEFMTLKTPVISIILGEGGSGGALALAVCDELAMLENALYSVISPKGFASILWKDASREREACDIMKITAEDLVRLKVCDHIIPEADGGAHNDPTLTAENISAFISESLQNLQRKFQKGLDEMINSRYNKFRVVGDFEESPHSDNKCCESCTENTSNV
>NC_014833.1|WP_013499720.1|3534766_3535660_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MQFEDFFSVVRERLGNDKNDENSSRKKTDIPTGLLFKCPRCRNVTFIEEFNQNGKVCPNCNYHSRLSAKERLKITVDDGSFREFDRKMISKNPINFPGYDNKQKELREKTGLTDAVLTGRAKIRGLDIVIIVMDSNYMMASMGSVVGERITRAIEYATAHKLPVIAFTASGGARMQEGIVSLMQMAKTSGAVARHNEAGGLYISVMTDPTTGGVTASFASLGDIIIAEPKVLIGFAGRRVIEGTIKQKLPDDFQSAEFMLENGFVDMIVERNKMRRVLAHLIKLHKSPEVKEVAENE
>NC_014833.1|WP_013499719.1|3533396_3534767_+|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MFKKILIANRGEIAVRVIRAARELGIKTVAVYSTADKNALHAMIADEAICIGGAQSKDSYLNVRAIISACEITGAEAIHPGFGFLSENPAFARMCEKCGIVFIGPRATSIEMLGDKAQAKETMKENGVPVIMGSDGAISNIHAAKTLSRDLGYPVLVKASAGGGGRGIRIVRSEDELESQMKAAKQEALACFGNDEVYIEKFIENPKHIEIQILADDYGDVIYLGERDCSMQRRNQKVLEEAPSPAPFMTQELRERMGKAAVTAARVCGYRNAGTIEFLVDKNGDFYFMEMNTRIQVEHPITEAVTGIDLVKQQLLIASGERLTIKQEDVKLTGHAIECRINAEDPSKDFRPSPGKINSMFIPGGFGVRVDTAAYSGYEIPPYYDSMIGKLIVHGKNREEAIAKMNWALAEFIVDGVATNVDFQLKLIRRPEFIAGDYDNGFLNRTDILADERGED
>NC_014833.1|WP_002847779.1|3532945_3533377_+|3-hydroxyacyl-ACP-dehydratase-FabZ
MAVLMNKEQIMEVIPHRDPFLLIDEINELEVGKRVKATKYIKEDDFWFKGHFPQYPVTPGVLMVEMCAQAGAVALLALPENKGKIGFFGGINDCKFRQQVVPGDTLEIEVEIIKVKGPIGVGKALATVGGKKAVSCEITFAIK
>NC_014833.1|WP_154662746.1|3532493_3532913_+|hypothetical-protein
MNVLFLISPAIIIYDISLTCFNSSTRKKIAEQNEAEIQNKAEDTSDNLNQDLLPDYYTLEKMHLTDLDAIFDGKSAEEAHIAYDADKVRDKAMLRYQKEVEALWDSDKRRKMQENIPHPAEQDIQVNNVNSLFDGDKKT
>NC_014833.1|WP_013499717.1|3531568_3532039_+|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein
MSEKIYGQFDLETIEKLADIINSKELSELTITDGDKTITLKGKRCVPAPAPIPVMPPMGAPMGGIPAPAGSDIPAPAVSGIQVTAPIVGTFYAAPSPDSKPFVKVGDRVKKGDVIFIIESMKVMSEVPSEFDGVVKEICVQNGDAVEFGQTVMILE
>NC_014833.1|WP_013499726.1|3541832_3544790_-|ABC-transporter-permease
MFTLLLRKMRNTKWMVFCLLTGFIMASAMMSTIPIYMNASLQRMLVKDMEAFQEEYMIYPGSYNTSHSFKSKLSTDEQVRTMEEYTALAEKQFGELDLPVAGSKKVVLDNDLYCKSISVEAGETPARLTLGGMSDICEHSAASSGRMMTKGVRDDGVFECMATEKSLKTNGLALDTVYEIANLFDNEKSVKIEIVGLIDVADENDPFWAEGIDEAYTAAVFTDYDTMMNEMLPTKAVNISKASYNFFIDYTKLDIPELKAINSSYNSQKEVFKKNDTGFIIPAKDILTDYAKRSSQLTLLLWLLQIPVILMIIFYLFMVSKLNIEQEKNEIAVFKSRGAGNRQILGIYALESLVLGILTAIAGPFAGLGLCRILGASNGFLEFVNRRAMPVRLTAEAFLYAAAAVLVFFITTLVPIVPALRTTIVEHKQSKAKKKKLALWEKVGLDVILAGGSFAWLYYYKRTQAKLLDLGITDTTATVNPMMFVASTAFILGLGLFLIRIYPMLIRLISSAGKRFWSPAQYVSLNNIGRSATGRERFLMLFLVLTVSLGVFFANTARALNRNAEETVEYANGADIVLAEEWYSSKTEAAQKRSGPSANMGGGMQQAAEEDTDTATVVTYTEPVFERFEKLEGVQHAAKVFRRDGVTVKSSKMTVVKRSAEKKTEKKREDFLNQDMNAGSSNTDRNVQLMAVQPAGFSEVINFEQRLLPTHINNYLEALAEYAPGVILSSAFKDYGLELGDTVECEWGANEPFDATVLAFVDYWPGLDPYAEAGDGSYMDFAVMNFDYVNVQTNMEPYQVWIDLADDASVQGFYDSVEKAKIEVTGMTSAKQEIIAKKNDPMLQGMNGALTLGFITIMIMCIIGFLIYWILSIKSRTLQFGILRAMGMKYREIISMIVYEQILVSGVAIFAAIFIGGITSELFVPLFQSVLDVSSRVPEFAVIPVREDYLRLYTVIAVMLLAGFLVLGRLIGRINISKALKLGED
>NC_014833.1|WP_013499727.1|3544810_3545878_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MMKGLADIKKFICRTLPTMVCAAAVMMTSGCYLLPDEEEAAVPPAVKASEVSYTTVTAKRKDIEKKLVSTGTVTAERQYDLSYEKQSGVILDFNVRAGDKVKKGDAICEIDTSDLDDQIAEKELYLQKAKLNVDMIWESGGTQAQIDSAYVDVQLIERELNKLRERKDGSVLRSPIDGVVSQLADVREGDNVSSGQTVATVIDTTALYIAVKPDDMSKFSVDTKVQIRINENYYDGVVFMDPAALAVYQEEVKASHDKEDKTGIAYEADTIYVRFEGDIPADALGQLADVILVLDKAENVIVISNNLIKKVDGEKVVYVLKNGEKTAVPIETGLTTGSQSEIVSGINEGDELVLK
>NC_014833.1|WP_013499728.1|3546184_3547429_-|homoserine-dehydrogenase
MSKNVAVIGYGVVGSGTVELFMKNRESISNKIGRDCDIKYILDLRDFPESPFADRIIHDFDTILNDDEIEVVAEVVGGTTFAYEYTKKLLAKGKSVVTSNKALVAAYGAELLQLAQDNGCSYLFEASVGGGIPIIRPLYKCLAGNEIQQISGILNGTTNFILTKMIKDQMSFEDALKLAQQLGYAEADPTADVEGEDACRKICILGSLVYGKHIYPEMVHKSGITRITLDDVEYADNAGYVIKLIASVKRLEDGSLSAIVCPRLVPKSNMLASVDDVYNAVSVTGDGVGDVLFYGQGAGKLPTASAVVGDIIDCLRHNGRSLGIHWNESKKDEKFVVRYKDTNCSMYVRLKGKDVQTLKPSISEMFGKLMYIERANRPDDELAFITPNMVESDIDANLTILSHSAEIASKIRMF
>NC_014833.1|WP_013499729.1|3547482_3547929_-|ACT-domain-containing-protein
MADNDSGLVIVSADVLPDIVLKVLAAKRMRARGEVSTSTEACRAVGISRSAYYKYKDSVFNYEERLTNNIVSVYCTLRDEKGVLSSIISKLYELGTNILTINQNIPVDSVATVTFSVRFDRDTLNTQKLTEELSKVSGVVEAKIISGE
>NC_014833.1|WP_013499730.1|3548233_3548533_+|hypothetical-protein
MDIISEILETDRLAEEKLEQAKQERSRMLADCEKAVKRIHDNAESEAGLYRDFLFGEDTSEETAKVLKESEKEQLDALVEAYERCHEEWETEIIAAITG
>NC_014833.1|WP_013499731.1|3548563_3549598_+|V-type-ATPase-subunit
MLENYSSNATTAKIRAKYAQLFTIDDYRELAALRTVPEAAEYLSRSVRFREAFAEVDPNTVHRGFLEELIYRENFRTYIRLCKFQGLDKEPFFGFLIRRSEIDCILSIINRINSSLDRTFLPDLPGYLIKHLTIPVMELSLSQTYDDLVAGLKGTRYARVLKKIPVRDDGKADYTECELRLRSDYYAELLEQADKEFAGVVSEELKTMILREIDCRNIINAYRMKSYFGYSPEEIKRRSLNFYGIGKKNMERLYDAADPETMMDMVNHTIYGKNSPDTDNIEVEINSVKIRRLRHYLTGSTHAPVALYAFIILCDIEASNLVHIIEGIRYGVEAATIESQLITL
>NC_014833.1|WP_013499732.1|3549633_3551586_+|ATPase
MAIEKMALVNIIGRFEDLDETLIRCCDSGCFHIEPAFRNEANSTVKLLNEKNPFGVPLKEFASLATEMGIELKETQGTRFNGWTAEQFNELSENIDSEINEKNSERQALAKEVSDLEAAVLQVDHLRGMNSDFSKIFACKHTACRIGRMPADNLAKLQYYDQTFFFVPFETTKDFCWGMYFCAESDKELVDSIFRSMFFERIRLPDYVTGNTDEALKKLDSQIKEKKAKTEALDKELAALAKKHDATILEAYTALKKRYDIFELRRKVGAVKEKFYIKGFVPKKQADKFSEKFGDMDEVEVVLLPPDADAYVTPPTVLKNSWFTRPFAMLVEMYGLPKYNGFNPTAFVAITYTLLFGIMFGDLGQGLLLFLGGLILGRKSKQAGGIVARCGLSSMIFGTLYGSVFGFEELLDPIYESFGIDFLPLKIFKQSTFILLTAVGIGIFLILVSMLINIYIGFKEKNYEKAIFGCNGIAGLVFYASVCTGVICTIMLKIEVMSLPFKIFLIAIPLICIFCRVPFSIAVKYKKWKLSEDEEDMTIGGFIVENFFEMFEFLLSYVSNTMSFLRVGGFVLSHAGMMMVVMTLMNMANSFAMKPVTLVIGNLFVMAMEGMIVAIQIIRLEFYEVFSRFYESDGKEFVPMSVSFDTEVNI
>NC_014833.1|WP_013499733.1|3551610_3552057_+|ATPase
MLKIMLLPLAAVVLLTVPFILMAKKIKTGEKSAKAAFIGNLCTFAGIMLVGMIVPFTDLVAFAASEGSTVKEALTTGAGLGYLAAGLSVGLSCIGSGIAVGSGAPAAIGATSEDPKNFVKALIFVVLGEGIALYGLLISILIISNIGG
>NC_014833.1|WP_013499734.1|3552061_3552370_+|V-type-ATP-synthase-subunit-F
MKFYLLSDNIDTLMGMRLAGIEGKVVHGTQEVSAALDEAMAMKDVGIILMTEIALKQCPEKVMNYKLTRAEPLIVEIPDRHATANISDTISKYLAEAVGIKL
>NC_014833.1|WP_013499735.1|3552387_3552981_+|V-type-ATP-synthase-subunit-E
MTDQTQKLEKFKQAVFNEAAAKADEIIKETEQHCSGILAQAEAEARKFVSESRAKAEKEYKETSQRTESAGRLELRRKLLNARQEVVDKVFSNVREKLEAFRESAAYERLLVKRAEECAAAYPGKRGEVRVAAADMKYAAKLTCGGRFTVCESGNILLGGIMVVFPEDNLALDCTFDNEFDRQKSGFAGKAGLVFDM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014833_6	6.9\|1325806\|26\|NC_014833\|PILER-CR	1325806-1325831	26	NZ_CP019203	Salmonella enterica subsp. enterica serovar Infantis strain CFSAN003307 plasmid pCFSAN003307, complete sequence	117699-117724	5	0.808
NC_014833_6	6.9\|1325806\|26\|NC_014833\|PILER-CR	1325806-1325831	26	NZ_LN868945	Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 3, complete sequence	84157-84182	5	0.808
NC_014833_6	6.10\|1325872\|27\|NC_014833\|PILER-CR	1325872-1325898	27	MN655998	Escherichia phage E26, complete genome	93951-93977	6	0.778
NC_014833_6	6.10\|1325872\|27\|NC_014833\|PILER-CR	1325872-1325898	27	MK327932	Escherichia phage vB_EcoM_G2248, complete genome	95606-95632	6	0.778
NC_014833_5	5.7\|1313641\|34\|NC_014833\|CRISPRCasFinder,CRT	1313641-1313674	34	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	2467792-2467825	7	0.794
NC_014833_5	5.30\|1315194\|35\|NC_014833\|CRISPRCasFinder,CRT	1315194-1315228	35	MT939487	Erwinia phage pEa_SNUABM_47, complete genome	192592-192626	8	0.771
NC_014833_5	5.30\|1315194\|35\|NC_014833\|CRISPRCasFinder,CRT	1315194-1315228	35	MT939486	Erwinia phage pEa_SNUABM_12, complete genome	193339-193373	8	0.771
NC_014833_5	5.30\|1315194\|35\|NC_014833\|CRISPRCasFinder,CRT	1315194-1315228	35	NC_041917	Serratia phage BF, complete genome	193304-193338	8	0.771
NC_014833_5	5.30\|1315194\|35\|NC_014833\|CRISPRCasFinder,CRT	1315194-1315228	35	MT939488	Erwinia phage pEa_SNUABM_50, complete genome	192469-192503	8	0.771
NC_014833_5	5.40\|1315865\|34\|NC_014833\|CRISPRCasFinder,CRT,PILER-CR	1315865-1315898	34	CP003185	Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome	105947-105980	8	0.765
NC_014833_5	5.40\|1315865\|34\|NC_014833\|CRISPRCasFinder,CRT,PILER-CR	1315865-1315898	34	NC_019956	Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence	55295-55328	8	0.765
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	381803-381836	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	351206-351239	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	375752-375785	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	350912-350945	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	353186-353219	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	356583-356616	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	355423-355456	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	368234-368267	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	355423-355456	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	362215-362248	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	355415-355448	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	375752-375785	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	368234-368267	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	356583-356616	10	0.706
NC_014833_5	5.5\|1313507\|34\|NC_014833\|CRISPRCasFinder,CRT	1313507-1313540	34	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	357764-357797	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP020899	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence	381803-381836	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013525	Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence	351206-351239	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013554	Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence	375752-375785	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013588	Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence	350912-350945	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013560	Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence	353186-353219	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013577	Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence	356583-356616	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013549	Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence	355423-355456	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013529	Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence	368234-368267	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013534	Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence	355423-355456	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013539	Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence	362215-362248	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013545	Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence	355415-355448	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013565	Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence	375752-375785	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013582	Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence	368234-368267	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NZ_CP013571	Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence	356583-356616	10	0.706
NC_014833_5	5.8\|1313708\|34\|NC_014833\|CRISPRCasFinder,CRT	1313708-1313741	34	NC_010998	Rhizobium etli CIAT 652 plasmid pA, complete sequence	357764-357797	10	0.706
NC_014833_5	5.36\|1315599\|34\|NC_014833\|CRISPRCasFinder,CRT	1315599-1315632	34	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1175786-1175819	10	0.706
NC_014833_5	5.36\|1315599\|34\|NC_014833\|CRISPRCasFinder,CRT	1315599-1315632	34	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1078442-1078475	10	0.706
NC_014833_5	5.36\|1315599\|34\|NC_014833\|CRISPRCasFinder,CRT	1315599-1315632	34	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1078431-1078464	10	0.706
NC_014833_5	5.54\|1316804\|34\|NC_014833\|CRISPRCasFinder,CRT,PILER-CR	1316804-1316837	34	NZ_CP032703	Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence	331211-331244	10	0.706
NC_014833_5	5.54\|1316804\|34\|NC_014833\|CRISPRCasFinder,CRT,PILER-CR	1316804-1316837	34	NZ_CP054600	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed1, complete sequence	51558-51591	12	0.647

1. spacer 6.9|1325806|26|NC_014833|PILER-CR matches to NZ_CP019203 (Salmonella enterica subsp. enterica serovar Infantis strain CFSAN003307 plasmid pCFSAN003307, complete sequence) position: , mismatch: 5, identity: 0.808

aatgggactgaacaaatgtatttttc	CRISPR spacer
gacgggactgaacaaatgttttttga	Protospacer
.*.**************** ****

2. spacer 6.9|1325806|26|NC_014833|PILER-CR matches to NZ_LN868945 (Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 3, complete sequence) position: , mismatch: 5, identity: 0.808

aatgggactgaacaaatgtatttttc	CRISPR spacer
gacgggactgaacaaatgttttttga	Protospacer
.*.**************** ****

3. spacer 6.10|1325872|27|NC_014833|PILER-CR matches to MN655998 (Escherichia phage E26, complete genome) position: , mismatch: 6, identity: 0.778

gagtcgcagtttggcaacaaagaccat	CRISPR spacer
gagttgcagtttggcatcaaagagttc	Protospacer
****.*********** ****** . .

4. spacer 6.10|1325872|27|NC_014833|PILER-CR matches to MK327932 (Escherichia phage vB_EcoM_G2248, complete genome) position: , mismatch: 6, identity: 0.778

gagtcgcagtttggcaacaaagaccat	CRISPR spacer
gagttgcagtttggcatcaaagagttc	Protospacer
****.*********** ****** . .

5. spacer 5.7|1313641|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 7, identity: 0.794

tcgatacactgcttgataatcttaccgtgttatg	CRISPR spacer
ttgttgccctgcttgatgatcttaccgtgatagg	Protospacer
*.* *.* *********.*********** ** *

6. spacer 5.30|1315194|35|NC_014833|CRISPRCasFinder,CRT matches to MT939487 (Erwinia phage pEa_SNUABM_47, complete genome) position: , mismatch: 8, identity: 0.771

tccgtagaaaacattgtaaaaatttcgg-gcgtggc	CRISPR spacer
agtgtagaaaagattgtaaaaattgcggaacgtga-	Protospacer
  .******** ************ *** .****.

7. spacer 5.30|1315194|35|NC_014833|CRISPRCasFinder,CRT matches to MT939486 (Erwinia phage pEa_SNUABM_12, complete genome) position: , mismatch: 8, identity: 0.771

tccgtagaaaacattgtaaaaatttcgg-gcgtggc	CRISPR spacer
agtgtagaaaagattgtaaaaattgcggaacgtga-	Protospacer
  .******** ************ *** .****.

8. spacer 5.30|1315194|35|NC_014833|CRISPRCasFinder,CRT matches to NC_041917 (Serratia phage BF, complete genome) position: , mismatch: 8, identity: 0.771

tccgtagaaaacattgtaaaaatttcgg-gcgtggc	CRISPR spacer
agtgtagaaaagattgtaaaaattgcggaacgtga-	Protospacer
  .******** ************ *** .****.

9. spacer 5.30|1315194|35|NC_014833|CRISPRCasFinder,CRT matches to MT939488 (Erwinia phage pEa_SNUABM_50, complete genome) position: , mismatch: 8, identity: 0.771

tccgtagaaaacattgtaaaaatttcgg-gcgtggc	CRISPR spacer
agtgtagaaaagattgtaaaaattgcggaacgtga-	Protospacer
  .******** ************ *** .****.

10. spacer 5.40|1315865|34|NC_014833|CRISPRCasFinder,CRT,PILER-CR matches to CP003185 (Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome) position: , mismatch: 8, identity: 0.765

gataacccacaaacttttaatatatctataattt	CRISPR spacer
aaaaaatggcaaacatttaatgtatctataattt	Protospacer
.* ** . .***** ******.************

11. spacer 5.40|1315865|34|NC_014833|CRISPRCasFinder,CRT,PILER-CR matches to NC_019956 (Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence) position: , mismatch: 8, identity: 0.765

gataacccacaaacttttaatatatctataattt	CRISPR spacer
aaaaaatggcaaacatttaatgtatctataattt	Protospacer
.* ** . .***** ******.************

12. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

13. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

14. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

15. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctctaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

16. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

17. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

18. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

19. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

20. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

21. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

22. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

23. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

24. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

25. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

26. spacer 5.5|1313507|34|NC_014833|CRISPRCasFinder,CRT matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

27. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP020899 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

28. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013525 (Rhizobium phaseoli strain R744 plasmid pRphaR744c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

29. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013554 (Rhizobium phaseoli strain N931 plasmid pRphaN931b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

30. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013588 (Rhizobium phaseoli strain N161 plasmid pRphaN161c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctctaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

31. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013560 (Rhizobium phaseoli strain N841 plasmid pRphaN841c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

32. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013577 (Rhizobium phaseoli strain N671 plasmid pRphaN671c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

33. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013549 (Rhizobium phaseoli strain R611 plasmid pRetR611b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

34. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013529 (Rhizobium phaseoli strain R723 plasmid pRphaR723b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

35. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013534 (Rhizobium phaseoli strain R650 plasmid pRphaR650b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

36. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013539 (Rhizobium phaseoli strain R630 plasmid pRphaR630b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

37. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013545 (Rhizobium phaseoli strain R620 plasmid pRphaR620c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

38. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013565 (Rhizobium phaseoli strain N831 plasmid pRphaN831b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

39. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013582 (Rhizobium phaseoli strain N261 plasmid pRphaN261b, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

40. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP013571 (Rhizobium phaseoli strain N771 plasmid pRphaN771c, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

41. spacer 5.8|1313708|34|NC_014833|CRISPRCasFinder,CRT matches to NC_010998 (Rhizobium etli CIAT 652 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.706

tgcagaccaacgttctcgcgctgtgcctgtgcca	CRISPR spacer
cctccaccaaggttctcgcgctgtgccggtgaat	Protospacer
. .  ***** **************** ***

42. spacer 5.36|1315599|34|NC_014833|CRISPRCasFinder,CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 10, identity: 0.706

tcttaacgcgtccatttcttccgctgtcgcgccc	CRISPR spacer
aaggaacgcgtccatgtcttccggtgtcattcgc	Protospacer
    *********** ******* ****.. * *

43. spacer 5.36|1315599|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tcttaacgcgtccatttcttccgctgtcgcgccc	CRISPR spacer
aaggaacgcgtccatgtcttccggtgtcattcgc	Protospacer
    *********** ******* ****.. * *

44. spacer 5.36|1315599|34|NC_014833|CRISPRCasFinder,CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tcttaacgcgtccatttcttccgctgtcgcgccc	CRISPR spacer
aaggaacgcgtccatgtcttccggtgtcattcgc	Protospacer
    *********** ******* ****.. * *

45. spacer 5.54|1316804|34|NC_014833|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032703 (Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

tctgaaccgcctccgcctgtgccatcgccataag	CRISPR spacer
cgtcaaccgcctgcgcctgtgccagcgcccgttc	Protospacer
. * ******** *********** ****

46. spacer 5.54|1316804|34|NC_014833|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054600 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed1, complete sequence) position: , mismatch: 12, identity: 0.647

tctgaaccgcctccgcctgtgccatcgccataag	CRISPR spacer
cggacaccgcgtccgactgtgccatcgcctgcgc	Protospacer
.  . ***** **** *************   .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

448603 : 455338

Enterobacteria_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013497154.1\|448603_449491_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	7.2e-101	62.2
WP_013497155.1\|449505_450057_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	3.1e-46	52.5
WP_013497156.1\|450069_451098_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.9e-84	47.4
WP_013497157.1\|451099_452179_+	acyltransferase	NA	NA	NA	NA
WP_013497158.1\|452135_453023_+	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	5.6e-29	39.3
WP_013497159.1\|453039_454104_+	GDP-mannose 4,6-dehydratase	K7QJG5	Escherichia_phage	1.1e-23	26.5
WP_013497160.1\|454105_455338_+	nucleotide sugar dehydrogenase	M1IB49	Acanthocystis_turfacea_Chlorella_virus	6.3e-103	50.2

DBSCAN-SWA_2

523313 : 606009

Bacillus_phage(28.57%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013497216.1\|523313_524636_+\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	8.4e-29	25.8
WP_013497217.1\|524639_524960_+	hypothetical protein	NA	NA	NA	NA
WP_013497218.1\|524964_525447_+	hypothetical protein	NA	NA	NA	NA
WP_013497219.1\|525596_526337_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_013497220.1\|526525_527668_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	Q6GZ03	Mycoplasma_phage	1.5e-21	55.1
WP_013497221.1\|527831_528695_+	hypothetical protein	NA	NA	NA	NA
WP_013497223.1\|531198_532179_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_013497224.1\|532175_533948_+	dynamin family protein	NA	NA	NA	NA
WP_013497225.1\|533998_535024_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013497227.1\|537987_540147_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_013497228.1\|540545_541577_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	4.6e-06	25.9
WP_028504336.1\|544075_546139_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_013497232.1\|549572_552635_-	RICIN domain-containing protein	NA	NA	NA	NA
WP_013497233.1\|553036_553534_+	CarD family transcriptional regulator	NA	NA	NA	NA
WP_013497234.1\|553762_554392_+	flavodoxin family protein	NA	NA	NA	NA
WP_013497235.1\|554406_555162_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_013497236.1\|555293_555770_-	hypothetical protein	NA	NA	NA	NA
WP_013497237.1\|556070_556649_+	sporulation initiation factor Spo0A C-terminal domain-containing protein	NA	NA	NA	NA
WP_013497238.1\|556884_558003_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_013497239.1\|558154_559792_+	biosynthetic-type acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	6.9e-57	29.4
WP_013497240.1\|559802_560327_+	hypothetical protein	NA	NA	NA	NA
WP_013497241.1\|560518_561016_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_013497242.1\|561081_562107_+	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_013497243.1\|562309_563464_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_013497244.1\|563526_565086_+	protein phosphatase 2C domain-containing protein	NA	NA	NA	NA
WP_013497245.1\|565291_565480_+	hypothetical protein	NA	NA	NA	NA
WP_013497246.1\|565978_571600_+	NPXTG-anchored protein	NA	NA	NA	NA
WP_013497247.1\|572490_572874_+	sigma-70 family RNA polymerase sigma factor	S6ANS0	Bacillus_phage	1.0e-11	41.2
WP_154662871.1\|572858_573410_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013497249.1\|573544_573943_-	hypothetical protein	NA	NA	NA	NA
WP_013497250.1\|574592_577580_+	glycoside hydrolase family 9 protein	NA	NA	NA	NA
WP_013497251.1\|577747_578005_-	hypothetical protein	NA	NA	NA	NA
WP_013497252.1\|578666_579233_+	hypothetical protein	NA	NA	NA	NA
WP_013497253.1\|579250_579775_+	hypothetical protein	NA	NA	NA	NA
WP_013497254.1\|579859_580453_+	hypothetical protein	NA	NA	NA	NA
WP_013483548.1\|581094_581970_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013497255.1\|582040_582685_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_013497256.1\|582771_583467_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_013497257.1\|583481_585110_+	hydroxylamine reductase	NA	NA	NA	NA
WP_013497258.1\|585232_585883_+	fibronectin type III domain-containing protein	NA	NA	NA	NA
WP_013497259.1\|586155_588870_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_013497260.1\|588869_589571_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.4e-37	38.3
WP_013497261.1\|589649_590279_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_013497262.1\|590836_591079_+	hypothetical protein	NA	NA	NA	NA
WP_013497263.1\|591978_593043_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013497264.1\|593039_593960_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_013497265.1\|593984_595553_+	oxidoreductase/nitrogenase component 1	NA	NA	NA	NA
WP_013497266.1\|595552_596890_+	hydrogenase	NA	NA	NA	NA
WP_013497267.1\|596945_597866_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013497268.1\|598001_598256_+	hypothetical protein	NA	NA	NA	NA
WP_013497269.1\|598387_600766_-	hypothetical protein	NA	NA	NA	NA
WP_154662912.1\|600848_601223_-	hypothetical protein	NA	NA	NA	NA
WP_013497271.1\|602251_602599_-	hypothetical protein	NA	NA	NA	NA
WP_013497272.1\|603318_604155_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.1e-85	58.4
WP_013497273.1\|604462_604891_+	hypothetical protein	NA	NA	NA	NA
WP_013497275.1\|605133_606009_+\|transposase	IS1595 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

754231 : 792105

Paenibacillus_phage(42.86%)

transposase,integrase

attL 763025:763038|attR 793344:793357

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013497397.1\|754231_755422_-\|integrase	site-specific integrase	A0A2I7SC08	Paenibacillus_phage	2.7e-42	30.1
WP_050793253.1\|755536_757069_-	plasmid recombination protein	NA	NA	NA	NA
WP_013497399.1\|757233_757416_-	hypothetical protein	NA	NA	NA	NA
WP_013497400.1\|757419_757716_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013497402.1\|759557_760553_+	hypothetical protein	NA	NA	NA	NA
WP_013497403.1\|760705_761584_+	DNA adenine methylase	A0A1L2BX38	Bacteriophage	8.3e-49	37.5
WP_013497404.1\|761600_761774_+	hypothetical protein	NA	NA	NA	NA
WP_013497405.1\|761867_762725_+	type II restriction endonuclease	A0A2H4JAL2	uncultured_Caudovirales_phage	4.3e-26	27.4
WP_013497406.1\|762724_764443_+	AIPR family protein	D0UIM0	Aggregatibacter_phage	4.8e-77	31.8
763025:763038	attL	NA	NA	NA	NA
WP_013497407.1\|764442_765186_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_013483548.1\|765363_766239_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_080557244.1\|766355_766544_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_050793254.1\|766546_766915_+	hypothetical protein	NA	NA	NA	NA
WP_013483548.1\|767012_767888_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013497408.1\|768109_768634_+	hypothetical protein	NA	NA	NA	NA
WP_013497409.1\|768677_769094_-	hypothetical protein	NA	NA	NA	NA
WP_013497410.1\|769104_769377_-	hypothetical protein	NA	NA	NA	NA
WP_013497411.1\|769745_770927_-\|integrase	site-specific integrase	A0A0K2CZ62	Paenibacillus_phage	2.7e-39	27.9
WP_013497412.1\|771057_772254_-	plasmid recombination protein	NA	NA	NA	NA
WP_013497413.1\|772595_772769_-	hypothetical protein	NA	NA	NA	NA
WP_028504436.1\|772772_773069_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_028504435.1\|773155_774799_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_013497416.1\|774904_775924_+	hypothetical protein	NA	NA	NA	NA
WP_050793255.1\|776069_778478_+	N-6 DNA methylase	NA	NA	NA	NA
WP_013497417.1\|778474_779443_+\|transposase	IS5 family transposase	A0A077K814	Ralstonia_phage	3.7e-58	40.6
WP_028504447.1\|779516_780248_+	hypothetical protein	NA	NA	NA	NA
WP_013497418.1\|780249_782082_+	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_154662901.1\|782113_784312_+	AAA family ATPase	NA	NA	NA	NA
WP_013497420.1\|784335_785328_+	restriction endonuclease	NA	NA	NA	NA
WP_013497421.1\|785341_787018_+	ATP-binding protein	NA	NA	NA	NA
WP_037305011.1\|787074_787494_-	hypothetical protein	NA	NA	NA	NA
WP_013483496.1\|787625_787943_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_013483393.1\|787936_788293_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_013483890.1\|789888_790428_+	hypothetical protein	NA	NA	NA	NA
WP_013497424.1\|790914_792105_-\|integrase	site-specific integrase	A0A2I7SC08	Paenibacillus_phage	7.8e-42	29.8
793344:793357	attR	NA	NA	NA	NA

DBSCAN-SWA_4

840969 : 938515

Staphylococcus_phage(25.0%)

protease,integrase,transposase

attL 889730:889754|attR 947122:947146

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013483548.1\|840969_841845_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013497468.1\|841847_842201_-	hypothetical protein	NA	NA	NA	NA
WP_013497469.1\|842324_843617_-	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_154662906.1\|844853_845141_+	hypothetical protein	NA	NA	NA	NA
WP_013497472.1\|845220_845502_+	hypothetical protein	NA	NA	NA	NA
WP_013497473.1\|845498_846119_+	DUF5104 domain-containing protein	NA	NA	NA	NA
WP_013497474.1\|846140_846734_+	DUF5104 domain-containing protein	NA	NA	NA	NA
WP_013497475.1\|846733_846982_+	hypothetical protein	NA	NA	NA	NA
WP_013497476.1\|847374_847914_+	hypothetical protein	NA	NA	NA	NA
WP_043550630.1\|848079_848403_-	hypothetical protein	NA	NA	NA	NA
WP_043550632.1\|848406_848619_-	hypothetical protein	NA	NA	NA	NA
WP_013497477.1\|849384_850260_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013483393.1\|851243_851600_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_013483496.1\|851593_851911_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_050793259.1\|852792_853593_-	hypothetical protein	NA	NA	NA	NA
WP_013497479.1\|853676_854165_+\|transposase	transposase	Q9MBP7	Staphylococcus_prophage	2.7e-17	42.6
WP_013497480.1\|854510_855704_+	ATP-binding protein	NA	NA	NA	NA
WP_013497481.1\|855716_856799_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013497482.1\|857480_860483_+	glycoside hydrolase family 9 protein	NA	NA	NA	NA
WP_154662877.1\|860638_861052_-	hypothetical protein	NA	NA	NA	NA
WP_013497484.1\|861038_861281_-	hypothetical protein	NA	NA	NA	NA
WP_013497485.1\|861288_861483_-	hypothetical protein	NA	NA	NA	NA
WP_013497486.1\|862011_863169_-	dockerin type I repeat-containing protein	NA	NA	NA	NA
WP_013497487.1\|863456_864512_-	glycoside hydrolase family 11 protein	NA	NA	NA	NA
WP_013497488.1\|865184_865886_-	toxic anion resistance protein	NA	NA	NA	NA
WP_013497489.1\|865879_866770_-	hypothetical protein	NA	NA	NA	NA
WP_013497490.1\|866766_868911_-	AAA family ATPase	NA	NA	NA	NA
WP_013497491.1\|868921_870037_-	hypothetical protein	NA	NA	NA	NA
WP_013497492.1\|870362_871688_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_013497493.1\|872181_873429_-	DUF3810 family protein	NA	NA	NA	NA
WP_013497495.1\|875722_877765_+	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_013497496.1\|877946_878468_-	TetR/AcrR family transcriptional regulator C-terminal domain-containing protein	NA	NA	NA	NA
WP_013497497.1\|879565_880447_+	radical SAM protein	NA	NA	NA	NA
WP_013497499.1\|880714_881959_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.6e-50	52.4
WP_013497500.1\|882123_882999_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013483574.1\|883405_883882_-\|transposase	IS200/IS605 family transposase	W0UUZ0	Sulfolobus_monocaudavirus	9.1e-18	34.5
WP_013497501.1\|884410_888346_+	VWA domain-containing protein	NA	NA	NA	NA
WP_013497502.1\|888360_889395_+	hypothetical protein	NA	NA	NA	NA
889730:889754	attL	NA	NA	NA	NA
WP_013497503.1\|890998_891952_-	hypothetical protein	NA	NA	NA	NA
WP_013497504.1\|891980_892925_-	DUF4405 domain-containing protein	NA	NA	NA	NA
WP_154662846.1\|892941_893592_-	flavodoxin	NA	NA	NA	NA
WP_154662847.1\|893647_894739_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_013497507.1\|894770_895706_-	aldo/keto reductase	NA	NA	NA	NA
WP_013497508.1\|895719_896757_-	aldo/keto reductase	NA	NA	NA	NA
WP_013497509.1\|896753_897374_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_013497510.1\|897373_897925_-	flavin reductase family protein	NA	NA	NA	NA
WP_013497511.1\|898336_898921_-	hypothetical protein	NA	NA	NA	NA
WP_013497512.1\|898922_899783_-	hypothetical protein	NA	NA	NA	NA
WP_013497513.1\|899775_900633_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.3e-18	26.3
WP_013497514.1\|900632_901007_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_013497515.1\|901673_902402_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_013497516.1\|902414_902999_-	maltose O-acetyltransferase	NA	NA	NA	NA
WP_013497517.1\|903010_903586_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_013497518.1\|903660_904512_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.5e-50	38.5
WP_013497519.1\|904524_905031_-	flavodoxin	NA	NA	NA	NA
WP_013497520.1\|905247_906123_-	DMT family transporter	NA	NA	NA	NA
WP_013497521.1\|906290_906833_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_013497522.1\|907040_907670_-	response regulator transcription factor	NA	NA	NA	NA
WP_013497523.1\|907672_908749_-	sensor histidine kinase	NA	NA	NA	NA
WP_013497524.1\|908930_909881_+	ABC transporter ATP-binding protein	A7K9T9	Acanthocystis_turfacea_chlorella_virus	6.9e-09	24.1
WP_013497525.1\|909882_911013_+	ABC transporter permease	NA	NA	NA	NA
WP_013497526.1\|910999_912208_+	ABC transporter permease	NA	NA	NA	NA
WP_080557249.1\|912342_912864_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	1.5e-53	67.9
WP_080557250.1\|912829_912958_-\|transposase	transposase	NA	NA	NA	NA
WP_013497527.1\|913092_914910_-	leucine-rich repeat protein	NA	NA	NA	NA
WP_013497528.1\|915332_915962_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013497529.1\|916047_916545_+	hypothetical protein	NA	NA	NA	NA
WP_013497530.1\|916582_917275_+	hypothetical protein	NA	NA	NA	NA
WP_013497531.1\|917295_918081_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_013497532.1\|918502_919009_+	hypothetical protein	NA	NA	NA	NA
WP_013497533.1\|919018_919405_+	hypothetical protein	NA	NA	NA	NA
WP_013497534.1\|919811_920174_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_013497535.1\|922348_923191_+	sugar transferase	NA	NA	NA	NA
WP_013497536.1\|923355_923775_+	adenylyltransferase/cytidyltransferase family protein	A0A1V0SGE7	Hokovirus	3.5e-13	34.5
WP_013497537.1\|923785_925132_+	diguanylate cyclase	NA	NA	NA	NA
WP_013497538.1\|925456_926116_+	response regulator transcription factor	NA	NA	NA	NA
WP_013497539.1\|926229_926604_+	hypothetical protein	NA	NA	NA	NA
WP_013497540.1\|926632_927544_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	1.7e-36	42.9
WP_013497541.1\|927540_928347_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_013497542.1\|928357_929104_+	membrane protein	NA	NA	NA	NA
WP_013497543.1\|929118_929985_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_028504339.1\|930141_930795_-	phosphohydrolase	NA	NA	NA	NA
WP_080557252.1\|931215_931638_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A1L2CUT6	Pectobacterium_phage	1.2e-34	53.8
WP_013497545.1\|931799_932003_+	hypothetical protein	NA	NA	NA	NA
WP_154662848.1\|932555_932750_-	mobility-associated LCxxNW protein	NA	NA	NA	NA
WP_013497547.1\|932749_933517_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	5.0e-34	30.5
WP_193384650.1\|933513_934419_-	hypothetical protein	NA	NA	NA	NA
WP_013483808.1\|934559_935792_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013483768.1\|935788_936769_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013483433.1\|936761_937766_+\|integrase	site-specific integrase	S5W9T9	Leptospira_phage	1.0e-10	27.4
WP_043550888.1\|937882_938515_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
947122:947146	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2786545 : 2841585

Organic_Lake_phycodnavirus(18.18%)

transposase,integrase

attL 2828859:2828918|attR 2845382:2846407

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013499083.1\|2786545_2787733_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_013499084.1\|2787842_2788157_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013499085.1\|2788492_2789563_-	hypothetical protein	NA	NA	NA	NA
WP_013499086.1\|2790231_2790978_-	recombinase family protein	NA	NA	NA	NA
WP_013499087.1\|2791154_2791580_-	hypothetical protein	NA	NA	NA	NA
WP_050793287.1\|2791746_2792454_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_013499089.1\|2792539_2792935_-	cytidine deaminase	NA	NA	NA	NA
WP_013499090.1\|2793004_2795431_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	5.1e-173	42.5
WP_013499091.1\|2795652_2795898_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_013499092.1\|2795952_2796555_-	single-stranded DNA-binding protein	S5MNH0	Brevibacillus_phage	8.8e-26	52.3
WP_013499093.1\|2796627_2796918_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_013499094.1\|2797046_2798012_-	DUF2628 domain-containing protein	NA	NA	NA	NA
WP_013499095.1\|2798408_2799905_+	LCP family protein	NA	NA	NA	NA
WP_013499097.1\|2800550_2801384_+	glycosyltransferase	F2Y1U7	Organic_Lake_phycodnavirus	1.3e-19	31.7
WP_013499099.1\|2803712_2804675_+	6-phosphofructokinase	NA	NA	NA	NA
WP_013499100.1\|2805207_2806344_+	peptide chain release factor 2	NA	NA	NA	NA
WP_013499101.1\|2806701_2807595_-	DUF624 domain-containing protein	NA	NA	NA	NA
WP_013499102.1\|2807634_2808249_-	hypothetical protein	NA	NA	NA	NA
WP_013499103.1\|2808309_2809113_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	6.0e-22	28.6
WP_013499104.1\|2809294_2810503_-	response regulator	A0A1V0SGX0	Hokovirus	5.7e-40	30.4
WP_013499105.1\|2810725_2811238_+	dockerin type I repeat-containing protein	NA	NA	NA	NA
WP_013499106.1\|2811562_2811991_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_013499107.1\|2812007_2812409_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_013499108.1\|2812620_2813664_-	hypothetical protein	NA	NA	NA	NA
WP_013499109.1\|2813727_2814777_-\|integrase	site-specific integrase	H7BVE3	unidentified_phage	1.7e-101	52.2
WP_013499110.1\|2814763_2815540_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013499111.1\|2815711_2815966_+	hypothetical protein	NA	NA	NA	NA
WP_013499112.1\|2815946_2817623_+	phage/plasmid primase, P4 family	A0A2H4JBE3	uncultured_Caudovirales_phage	4.6e-16	23.8
WP_013499113.1\|2818034_2818397_+	hypothetical protein	NA	NA	NA	NA
WP_013499114.1\|2818542_2818755_+	hypothetical protein	NA	NA	NA	NA
WP_013499115.1\|2818880_2820698_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_013499116.1\|2820950_2822087_-\|integrase	site-specific integrase	A0A2R2ZGM9	Clostridioides_phage	6.1e-28	24.7
WP_013499117.1\|2822196_2823393_-	plasmid recombination protein	NA	NA	NA	NA
WP_154662713.1\|2823762_2824314_-	DNA primase	NA	NA	NA	NA
WP_013499119.1\|2824352_2824571_-	hypothetical protein	NA	NA	NA	NA
WP_013499120.1\|2824585_2824876_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_154662712.1\|2824976_2826599_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_013499122.1\|2826716_2827736_+	hypothetical protein	NA	NA	NA	NA
WP_013499123.1\|2827810_2828515_-	TIGR02391 family protein	NA	NA	NA	NA
WP_050793289.1\|2828529_2828907_-	hypothetical protein	NA	NA	NA	NA
2828859:2828918	attL	NA	NA	NA	NA
WP_013483548.1\|2828973_2829849_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_050793290.1\|2829851_2830487_-	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_013499124.1\|2830483_2831308_-	Eco47II family restriction endonuclease	NA	NA	NA	NA
WP_013499125.1\|2831307_2832531_-	DNA (cytosine-5-)-methyltransferase	F2Y148	Organic_Lake_phycodnavirus	9.6e-80	46.2
WP_013499127.1\|2832929_2834486_+	hypothetical protein	E4ZFP0	Streptococcus_phage	1.8e-06	28.0
WP_013499128.1\|2834517_2834934_-	hypothetical protein	NA	NA	NA	NA
WP_013499129.1\|2834937_2835249_-	hypothetical protein	NA	NA	NA	NA
WP_013499130.1\|2835780_2836074_-	hypothetical protein	NA	NA	NA	NA
WP_013483768.1\|2839607_2840588_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013483433.1\|2840580_2841585_+\|integrase	site-specific integrase	S5W9T9	Leptospira_phage	1.0e-10	27.4
2845382:2846407	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3004888 : 3046402

Hokovirus(20.0%)

protease,transposase,integrase

attL 3021949:3021973|attR 3052479:3052503

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013499267.1\|3004888_3007186_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2I7SAX5	Vibrio_phage	4.7e-112	34.0
WP_013499269.1\|3007511_3008987_-	stage IV sporulation protein A	NA	NA	NA	NA
WP_013499270.1\|3009001_3010549_-	DUF3794 domain-containing protein	NA	NA	NA	NA
WP_154662801.1\|3010631_3010796_+	hypothetical protein	NA	NA	NA	NA
WP_013499271.1\|3010820_3011075_+	hypothetical protein	NA	NA	NA	NA
WP_013499272.1\|3011208_3012498_-	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	NA	NA	NA	NA
WP_013499273.1\|3012908_3013838_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013499274.1\|3013971_3015864_+	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	4.3e-87	32.0
WP_013499275.1\|3016159_3017137_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_154662803.1\|3017559_3021198_+	hybrid sensor histidine kinase/response regulator	A0A1V0SGX0	Hokovirus	5.1e-44	29.0
WP_013499277.1\|3021254_3021596_-	type II toxin-antitoxin system PemK/MazF family toxin	Q332J9	Clostridium_botulinum_C_phage	1.7e-10	35.0
3021949:3021973	attL	NA	NA	NA	NA
WP_013499278.1\|3022117_3023329_-\|integrase	site-specific integrase	A0A0K2CZ62	Paenibacillus_phage	1.3e-44	30.9
WP_013499279.1\|3024862_3025084_+	hypothetical protein	NA	NA	NA	NA
WP_013499280.1\|3025095_3025302_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013499281.1\|3025294_3026122_+	hypothetical protein	NA	NA	NA	NA
WP_154662908.1\|3026279_3026507_+	hypothetical protein	NA	NA	NA	NA
WP_013499283.1\|3026873_3027692_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_013499284.1\|3027686_3028109_-	hypothetical protein	NA	NA	NA	NA
WP_157865481.1\|3028301_3028886_+	protein kinase	A0A1V0SH95	Hokovirus	1.0e-15	33.1
WP_013499286.1\|3028955_3029309_-	helix-turn-helix transcriptional regulator	A0A077KGZ5	Edwardsiella_phage	1.7e-05	44.8
WP_013499287.1\|3029460_3029931_+	hypothetical protein	NA	NA	NA	NA
WP_013497884.1\|3029947_3030823_-\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_013499288.1\|3030947_3031121_+	hypothetical protein	NA	NA	NA	NA
WP_013499289.1\|3031137_3032034_+	hypothetical protein	NA	NA	NA	NA
WP_013499290.1\|3032178_3032331_+	hypothetical protein	NA	NA	NA	NA
WP_013499291.1\|3034001_3034202_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013497097.1\|3034517_3035693_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	4.0e-14	29.8
WP_154662907.1\|3036163_3037375_-	AAA family ATPase	NA	NA	NA	NA
WP_028504474.1\|3037696_3038140_-	hypothetical protein	NA	NA	NA	NA
WP_154662909.1\|3038737_3039712_+	hypothetical protein	NA	NA	NA	NA
WP_013499294.1\|3039738_3040320_+	hypothetical protein	NA	NA	NA	NA
WP_013499295.1\|3041208_3041688_+	hypothetical protein	NA	NA	NA	NA
WP_013499297.1\|3041989_3042472_+	hypothetical protein	NA	NA	NA	NA
WP_013499298.1\|3042477_3043020_+	hypothetical protein	NA	NA	NA	NA
WP_013499299.1\|3043391_3044510_-\|integrase	site-specific integrase	A0A0K2CZ62	Paenibacillus_phage	4.1e-37	31.1
WP_013499291.1\|3044710_3044911_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013497097.1\|3045226_3046402_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	4.0e-14	29.8
3052479:3052503	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014824

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_014825

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_014833

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection