CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_014758	Calditerrivibrio nitroreducens DSM 19672, complete sequence	3 crisprs	csa3,DEDDh,Cas9_archaeal,cas3,DinG,cas2,PrimPol,cas1,csx20,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas6,WYL,cas7,cas5,cas4	0	3	1	0
NC_014749	Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence	1 crisprs	cas14j	0	5	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_014758_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014758_1

1652519-1654555

TypeIII

Consensus_repeat	Method
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	CRISPRCasFinder
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	CRT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	PILER-CR

27 spacers

cas1,PrimPol,cas2,csx20,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

The CRISPR arrays of NC_014758_1

>merge|NC_014758|1|1652519-1654555|CRISPRCasFinder,CRT,PILER-CR
TCCTTGCTTGCGCAAAGTCAGGTCAATGATTCCAACTTTATTATCTCATCCAGTGACTGAAGTAGCCTCCGTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAACTTACAGACATCAAGAGTTGAACTTAATAGCTCAGTTGGTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAACGAGGAAGCTATGAGGCTAAAAGAAGTTTTAAAAAGTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAACAGATACGTCGGGGTTAAATTAAACCAGGATGAGATCAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACAATAATAGTATAAACCAAAATAGTCTGACCGAGAATAGGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACAAAAGAAAATAGATGTGAGCATATATGCAGATCCAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACAGAGTAAGCCCAAAAGATTAGTTATGTTTAAAATAAAAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACAAAATGGAGTTAAAAAATATGATTGAAAAATATGTAGGAAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACGAAAATCTACACTAGCTAAGTTGACCTCTGAAGAACTTAAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACTGAGATGTATAGCTTGCAATGAAATCATTGACGATTTTTGTCGCAATCCTTTAAAGTCAGGTCAATGTTTCCAACTTCATTACATTTTTGGAAAATAGACAGGGGTTTCACGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACGAAAATTGTGGAGAAGTAGTAAGAGAGGGGGAGGATTATGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACTAATCATAAATAAAAATTCTATAGTTGTTAACGCTAACAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACGATCCAGTTTACAAACCTTCATTTTATGCAAATAGATAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACGGATTATCTGTATTATTGTGAGTATTGTGGTGAGTATGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACGGGCTATTAAAGCCCCATAAAAAAATAAAAAGGGGCTATGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACTTAGATGTGTCTATATACGCTAAGCCTGATTTTGATTGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACTAACCCCTATAGCTCGGGAGTTCTTGCGAGAGCGATTGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACCATATTGTGGATGCGGTTTATGAAAATGATACCTTTCTCGTGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACAGAAAATTAGAGAAAGAAAAAATAAAAAAAGATATGATGGGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACGATGAAGTTTTAAAACTGTTAGAGGAAGGAATAATCCTCGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACTAAGAGGGCATCTGGCAGAGGAAATTGTCAAGAGATTAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACTACATACGATAAAGAAATTTTAAAAATAAAAGATAAACGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACAAGAAAAAGACGCTTTGATAAAAAAAAATGAAAATAAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAACAAATAGCCCGTCGCATAGGGGTAGATAGGACAGCAATAGTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC

>NC_014758|1|1|1652519-1654555|CRISPRCasFinder
TCCTTGCTTGCGCAAAGTCAGGTCAATGATTCCAAC	TTTATTATCTCATCCAGTGACTGAAGTAGCCTCC
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	TTACAGACATCAAGAGTTGAACTTAATAGCTCAGTTG
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	GAGGAAGCTATGAGGCTAAAAGAAGTTTTAAAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	AGATACGTCGGGGTTAAATTAAACCAGGATGAGATCAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AATAATAGTATAAACCAAAATAGTCTGACCGAGAATAG
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAAAGAAAATAGATGTGAGCATATATGCAGATCCAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AGAGTAAGCCCAAAAGATTAGTTATGTTTAAAATAAAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAAATGGAGTTAAAAAATATGATTGAAAAATATGTAGGAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GAAAATCTACACTAGCTAAGTTGACCTCTGAAGAACTTAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	ACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	ACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TGAGATGTATAGCTTGCAATGAAATCATTGACGATTTTT
GTCGCAATCCTTTAAAGTCAGGTCAATGTTTCCAAC	TTCATTACATTTTTGGAAAATAGACAGGGGTTTCAC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GAAAATTGTGGAGAAGTAGTAAGAGAGGGGGAGGATTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAATCATAAATAAAAATTCTATAGTTGTTAACGCTAACAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GATCCAGTTTACAAACCTTCATTTTATGCAAATAGATAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GGATTATCTGTATTATTGTGAGTATTGTGGTGAGTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GGGCTATTAAAGCCCCATAAAAAAATAAAAAGGGGCTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TTAGATGTGTCTATATACGCTAAGCCTGATTTTGATT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAACCCCTATAGCTCGGGAGTTCTTGCGAGAGCGATT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	CATATTGTGGATGCGGTTTATGAAAATGATACCTTTCTCGT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AGAAAATTAGAGAAAGAAAAAATAAAAAAAGATATGATGG
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GATGAAGTTTTAAAACTGTTAGAGGAAGGAATAATCCTC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAAGAGGGCATCTGGCAGAGGAAATTGTCAAGAGATTAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TACATACGATAAAGAAATTTTAAAAATAAAAGATAAAC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAGAAAAAGACGCTTTGATAAAAAAAAATGAAAATAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAATAGCCCGTCGCATAGGGGTAGATAGGACAGCAATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC

>NC_014758|1|1|1652519-1654555|CRT
TCCTTGCTTGCGCAAAGTCAGGTCAATGATTCCAAC	TTTATTATCTCATCCAGTGACTGAAGTAGCCTCC
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	TTACAGACATCAAGAGTTGAACTTAATAGCTCAGTTG
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	GAGGAAGCTATGAGGCTAAAAGAAGTTTTAAAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	AGATACGTCGGGGTTAAATTAAACCAGGATGAGATCAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AATAATAGTATAAACCAAAATAGTCTGACCGAGAATAG
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAAAGAAAATAGATGTGAGCATATATGCAGATCCAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AGAGTAAGCCCAAAAGATTAGTTATGTTTAAAATAAAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAAATGGAGTTAAAAAATATGATTGAAAAATATGTAGGAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GAAAATCTACACTAGCTAAGTTGACCTCTGAAGAACTTAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	ACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	ACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TGAGATGTATAGCTTGCAATGAAATCATTGACGATTTTT
GTCGCAATCCTTTAAAGTCAGGTCAATGTTTCCAAC	TTCATTACATTTTTGGAAAATAGACAGGGGTTTCAC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GAAAATTGTGGAGAAGTAGTAAGAGAGGGGGAGGATTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAATCATAAATAAAAATTCTATAGTTGTTAACGCTAACAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GATCCAGTTTACAAACCTTCATTTTATGCAAATAGATAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GGATTATCTGTATTATTGTGAGTATTGTGGTGAGTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GGGCTATTAAAGCCCCATAAAAAAATAAAAAGGGGCTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TTAGATGTGTCTATATACGCTAAGCCTGATTTTGATT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAACCCCTATAGCTCGGGAGTTCTTGCGAGAGCGATT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	CATATTGTGGATGCGGTTTATGAAAATGATACCTTTCTCGT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AGAAAATTAGAGAAAGAAAAAATAAAAAAAGATATGATGG
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GATGAAGTTTTAAAACTGTTAGAGGAAGGAATAATCCTC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAAGAGGGCATCTGGCAGAGGAAATTGTCAAGAGATTAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TACATACGATAAAGAAATTTTAAAAATAAAAGATAAAC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAGAAAAAGACGCTTTGATAAAAAAAAATGAAAATAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAATAGCCCGTCGCATAGGGGTAGATAGGACAGCAATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC

>NC_014758|1|1|1652662-1654555|PILER-CR
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	GAGGAAGCTATGAGGCTAAAAGAAGTTTTAAAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	AGATACGTCGGGGTTAAATTAAACCAGGATGAGATCAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AATAATAGTATAAACCAAAATAGTCTGACCGAGAATAG
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAAAGAAAATAGATGTGAGCATATATGCAGATCCAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AGAGTAAGCCCAAAAGATTAGTTATGTTTAAAATAAAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAAATGGAGTTAAAAAATATGATTGAAAAATATGTAGGAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GAAAATCTACACTAGCTAAGTTGACCTCTGAAGAACTTAAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	ACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	ACGGATATGTTTTTTTTATTAGAAAAAACGATGAGATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TGAGATGTATAGCTTGCAATGAAATCATTGACGATTTTT
GTCGCAATCCTTTAAAGTCAGGTCAATGTTTCCAAC	TTCATTACATTTTTGGAAAATAGACAGGGGTTTCAC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GAAAATTGTGGAGAAGTAGTAAGAGAGGGGGAGGATTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAATCATAAATAAAAATTCTATAGTTGTTAACGCTAACAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GATCCAGTTTACAAACCTTCATTTTATGCAAATAGATAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GGATTATCTGTATTATTGTGAGTATTGTGGTGAGTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GGGCTATTAAAGCCCCATAAAAAAATAAAAAGGGGCTAT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TTAGATGTGTCTATATACGCTAAGCCTGATTTTGATT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAACCCCTATAGCTCGGGAGTTCTTGCGAGAGCGATT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	CATATTGTGGATGCGGTTTATGAAAATGATACCTTTCTCGT
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AGAAAATTAGAGAAAGAAAAAATAAAAAAAGATATGATGG
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	GATGAAGTTTTAAAACTGTTAGAGGAAGGAATAATCCTC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TAAGAGGGCATCTGGCAGAGGAAATTGTCAAGAGATTAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	TACATACGATAAAGAAATTTTAAAAATAAAAGATAAAC
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAGAAAAAGACGCTTTGATAAAAAAAAATGAAAATAA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC	AAATAGCCCGTCGCATAGGGGTAGATAGGACAGCAATA
GTCGCAATCCCTTAAAGTCAGGTCAATGTTTCCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014758.1\|WP_013451721.1\|1651027_1651387_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013451727.1\|1658660_1659050_-\|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_014758.1\|WP_013451726.1\|1657932_1658484_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013451724.1\|1656441_1657296_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013451718.1\|1648495_1649503_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_014758.1\|WP_013451719.1\|1649521_1650793_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|379646
NC_014758.1\|WP_013451714.1\|1644163_1645504_-\|flagellar-protein-FlgN	unknown	unknown	gnl\|CDD\|224117
NC_014758.1\|WP_013451723.1\|1654932_1656441_-\|SAVED-domain-containing-protein	unknown	unknown	gnl\|CDD\|380122
NC_014758.1\|WP_013451731.1\|1661827_1662295_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_014758.1\|WP_013451728.1\|1659055_1660195_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	mkCas0182_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_014758.1\|WP_013451715.1\|1645503_1646169_-\|ComF-family-protein	unknown	unknown	gnl\|CDD\|223970
NC_014758.1\|WP_013451712.1\|1641971_1643138_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NC_014758.1\|WP_013451713.1\|1643187_1644186_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NC_014758.1\|WP_013451717.1\|1646728_1648489_+\|DNA-primase	PrimPol	COG4951_PrimPol_CAS-I:CAS-III	gnl\|CDD\|227287
NC_014758.1\|WP_013451730.1\|1661131_1661809_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_014758.1\|WP_013451716.1\|1646328_1646610_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_014758.1\|WP_013451725.1\|1657304_1657940_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013451729.1\|1660191_1661124_-\|crispr-associated-protein,-csm4-family	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	gnl\|CDD\|224483
NC_014758.1\|WP_013451722.1\|1651467_1651833_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013451732.1\|1662291_1664670_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811

Protein	Function_ID	Function_description	E-value
NC_014758.1\|WP_013451730.1\|1661131_1661809_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.37364e-67
NC_014758.1\|WP_013451718.1\|1648495_1649503_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	3.27229e-112
NC_014758.1\|WP_013451719.1\|1649521_1650793_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|379646	pfam14559, TPR_19, Tetratricopeptide repeat.	7.70182e-06
NC_014758.1\|WP_013451714.1\|1644163_1645504_-\|flagellar-protein-FlgN	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.00118382
NC_014758.1\|WP_013451723.1\|1654932_1656441_-\|SAVED-domain-containing-protein	gnl\|CDD\|380122	pfam18145, SAVED, SMODS-associated and fused to various effectors sensor domain. Predicted to function as a sensor domain, sensing nucleotides or nucleotide derivatives generated by SMODS and other nucleotide synthetase domains. The sensing of ligands by SAVED is predicted to activate effectors deployed by a class of conflict systems which are reliant on the on the production and sensing of the nucleotide second messengers.	2.07234e-11
NC_014758.1\|WP_013451731.1\|1661827_1662295_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	4.86554e-14
NC_014758.1\|WP_013451728.1\|1659055_1660195_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	2.81416e-12
NC_014758.1\|WP_013451715.1\|1645503_1646169_-\|ComF-family-protein	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	3.04582e-34
NC_014758.1\|WP_013451712.1\|1641971_1643138_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NC_014758.1\|WP_013451713.1\|1643187_1644186_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NC_014758.1\|WP_013451717.1\|1646728_1648489_+\|DNA-primase	gnl\|CDD\|227287	COG4951, COG4951, Uncharacterized protein conserved in bacteria [Function unknown].	7.00174e-18
NC_014758.1\|WP_013451716.1\|1646328_1646610_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.38593e-27
NC_014758.1\|WP_013451729.1\|1660191_1661124_-\|crispr-associated-protein,-csm4-family	gnl\|CDD\|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	4.45883e-10
NC_014758.1\|WP_013451732.1\|1662291_1664670_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	4.28914e-136

>NC_014758.1|WP_013451722.1|1651467_1651833_-|hypothetical-protein
MRNLKILFWNVKNKDAELFHDIESYNADIIALSEVRKFNIDRYQSFFEKKGFNYFTSLDLFDDIALSNNTNLLMVAGKGISLDNLKLSLDELGEHRLKFMQVSTEEGLKLGVYHSMNCKTM
>NC_014758.1|WP_013451721.1|1651027_1651387_-|hypothetical-protein
MGDFNAILFDANAKENPFVYEIKDKYYNFSENINKVLSRYPSFNHKAKKFLGAFGNMPRNFYYIKPENGLEQVSLDGKFKTLIGHAFVIEDLLENKPMVTYGEKSASDHKPIILIFGNQ
>NC_014758.1|WP_013451719.1|1649521_1650793_+|tetratricopeptide-repeat-protein
MEDSDKKRKEAMLLRQQHRYEEALPIYRQLWENDQRNPWDGWGLALCLQQLKQYKESIDICEEIIKKHGNYDYIKNLYIWSLFYYIKNETLSNDEFEYIAKKILENTTNEDKIFSAVILKWIHRLKGEPNYPALKILKLLDMLDINRLNKEALEITQDGKKIEIASEYEQYFMHKSKALYELSEYEKCIEISNAAITSLKRFHYNNDIWFKWRIALSFKNMQRYDESLEKLIEIVRIKKDWFIQKEIAEIYFIQNKYDDALSFAIDSILNAGEIDKKIYVIILLCEIFEKKQMHYEAGLHYLLAKNIIDKNGWKIQVPIQLKDKFNDFGAQANDIHRELKKIWNQINDAKMDRYDGIIINYLSNNQAGFIKCHNQTYYFKVADLYGKKEDYSIGTKVTFSLVDSYDKKKNKPVKNAVKIKKIS
>NC_014758.1|WP_013451718.1|1648495_1649503_+|CRISPR-associated-endonuclease-Cas1
MVVYINEQGAVINISGERIILKKAGQIIAVFLTKDLDQVVLMGNIGLTTQSIRHFLQNKIDVVFTSASGKYEGRLVQELGKNVALRRLQFEATQDEKFKFKIAKSIIYGKYKNSISALRKLNYYHKSKEVSDILNQLTARHNDLTAAETYESLLGYEGIISSIYFSAFDCLLNKEIKFEKRTRRPPQNEFNALLSFGYTILSNLIRTEVYITGLDPYFGVLHAEDYGRPSLVLDLMEEFRAIAVDMPAINAVNKGLITKSDFVLNDDGDEDHLPIQLTIFGRKKWLSILEKRFNSFLWFQPKNQKTTLRNIIKYQCYLISKSFIEKAIYQPFILI
>NC_014758.1|WP_013451717.1|1646728_1648489_+|DNA-primase
MMEQDLNIQELTQKIEEYERNNEFDRMIQYLNLGLQKDPTNKNFLLKILDYYLNDANPSRALKTLEKLIRLEPDNSVYYKQAITILLEFNKIELAKKLAKIGFSNTNDQSIVDMIKNIENSTANSSITPMLEDFDKETVTLLYSLFSGREGVYARQWKNTEGVTGYIPVREPLNEKTIINHLNGNITIGIYQHRLDSTINWICFDIDIAKHVLNNALTNNDYFKELDNLCQDIAVEIYDECAKFNIPVYLENSGYKGRHCWIFAEKPINARIAKKFGDTLKANLKKIIPEVSVEVFPKQNFVKPDGLGNLVKLPLGIHIATGKRSFFVDRHGKEIKNVNDFLKKIGKTDEKRLIEYLNYYRIETIYSEYSKKSTSPGETISFPQPHKSFNLETDRSFQYIIYKCPVIKELYNNAIKKNELSYDEMIVITHTLGHLENGVEIVNSIFSKCFNVSAEKYLKSQLKGNPISCARIRSKIPEITSSVNCNCQFVNTEGLYPSPVLHFNTKEIPSKLPILINVDMLNFQNVLDSYISLKKQYFEISLTLKEYEEKFETLFKTSGVDKINTPIGTFRRVVDENGKISYKIDV
>NC_014758.1|WP_013451716.1|1646328_1646610_-|CRISPR-associated-endonuclease-Cas2
MEKFYVISYDIADDRKRYRVDKLLKNNGMRVQKSVFECRLTDAQFLTLKMELGKIINYNTDSVRFYYLCKHCVDMIEYIGNSVFLEKNDFLII
>NC_014758.1|WP_013451715.1|1645503_1646169_-|ComF-family-protein
MFDEIFYSECLYCSTAVMYRETICEACFSEIKKVIHRCRLCGYPLNVEAEVCKNCLESKYYDKLFIPFWYTSVVKSVLKKIKFRYNIKGYRLIDELVRKNLMKMDRYDVITYVPSTFMRRFRRFVHPAEYIANILSDIYMTPCEPLLKRVRNTSYQWRLKKKERLKNVSEAFTPKKELFDLKILLVDDIITTGATLNECAKMLKGAGARKVDCYVLSKGLF
>NC_014758.1|WP_013451714.1|1644163_1645504_-|flagellar-protein-FlgN
MIDIEQLLTYINLEEFTNIFVYHQDEHVFRYYSNGKFVNTEVPDFLKRHLLNDNTSLYLFRKNDNILTFYFFRLHIQNKHFVVIIQDSKDGKYLNRFISSLFENLWELKLGSVQLNKEIDFLRDELNVCEKELNEKEQELNRLSELLSSKETLLESLEESVSILKKSRQKMLKLIDGFNMPFFSMDINYDLNNVNLAAGKFAGETNLPRLVGGKCFKMIYNFPEPCKWCKYEEIKQTKSCVKQHIHYEKDGVKYVFEQSMFPIFDQDGNLIEVGEYINDITHQYELLESLKKSEQELVQVSKKNIESINEIGALKKAYEDLSNEYEKAKAKIAKLTSVLGTLVQQDTVNELLQLRGEKKELEIKLAKALTIIKNFTKKHEENESKIESIAKKSLYSVERLLNILNNKKKIDDEELKKVFDFLSGQILYIKQIIEKQEEKNESKSSN
>NC_014758.1|WP_013451713.1|1643187_1644186_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MSLKVAINGFGRIGRCAFRAAYARKLDIDFVAINDLTDAKTLAHLLKYDSVHGIADLEVSYKDDSLIVNGKTIKVYAIKDPAQLPWKDLGVDVVLESSGIFTKREGASKHLTAGAKKVVISAPAEDPDITVALGVNFETYDKNKHHIISNASCTTNCLAPVAKVIHKKFGIINGLMTTIHSYTNDQRILDLPHKDLRRARAAALSMIPTSTGAAKAVGLVLPELKGKLDGLAIRVPTPNVSLVDLTCNVSKAVTKEEVNAAIKEAAEGEMKGILQYVDTELVSTDFNGNPHSSIFDAPLTKVIDGTCVKVFSWYDNEWGYSNRVAELLTKLF
>NC_014758.1|WP_013451712.1|1641971_1643138_-|phosphoglycerate-kinase
MVRSVESLDVKGRRVFLRVDFNVPIKNGVVKDDTRIVEALKTINYLKEKGAKVIMASHLGRPKGEFNLEYSLKPVSEYFSAKFFPIKFVDDCIGEKVHSTVNDMKDGDVILLENLRFYKGEEKNLPEFSAALKEFTDVYVNDAFGTCHRKHASVFGLPELVEDKGAGFLVKKEVEYFEKLLKSPEKPFIAILGGAKVSDKIGVIKSLINLVDEIIIGGAMAYTFLKFLGKNTGKSLVENEYLGVVDETMKLSEEKGVKILLPIDHVCSDVFDGEPEYVSGVDIPDDLMGLDIGPATVELFEKEVLKAKTILWNGPMGVFENDNYNKGTFAIASALASSGAVTVVGGGDSVNAIKKAGVADKISHISTGGGASLEYIEFGSLPGIEILK
>NC_014758.1|WP_013451723.1|1654932_1656441_-|SAVED-domain-containing-protein
MSPLSKYFEPEKYKILLNSIRDGNFLPGLELEDYYRAFSDETFRDEEYLKSTLFLAIRRYSKFQNLKLLSNHFKMDEDNLRVLLNEDYKIASFPIVDNSQAELANLYVIELEDNCQTLSFPNTDMFRLDYLQNIKKALGKNFFVFFDRFFTGRSFGLALAACFFIKDEIREKLLFTGEVRADGRVYDVDGIGLKTEIAKANKRYLVGSTHVNSITELKYLDRNCIDVPFIQLFGKSKNELNKNFSKLKEFISDGRVMVDVLGFSDENLSVFCEDFIENNIDTYLNYLRDFYYKVKRVYEIDFEVNLHLLGSLSSFAFLMGLVLGAKKRFVIYHYQDGGVHKVFDFMKQSVRVLKSKKNHYEYLKFQIFYNDPDSDELLVSLYIASHNPVNDAAKFAKEKLNCNMVEIRLKEQQGYLPLDNEKIWIDVVSEIYSLLTENILDFKNVIKKYHFIFSVPVPIAFALGMAIGDYKKILVYNFDKQIGSYIKVFDSDLKEELPMNAF
>NC_014758.1|WP_013451724.1|1656441_1657296_-|hypothetical-protein
MSKRLEKIYAAYLKLKDKDEGLSTQKKGDYKMFLNKLKRPVKYSKITPEYRLGELFFVDDFIFLLTGEAEDFYTGFKVSEWVDFATHEDFVFEFDGNKWFAIMEHELYIPRNEVIHYIGELSEEYSDVLFEYVVGEEKLPTKYTGLTIPYDNNYIQVKFRQEEMKKVKHYIANQFTIIDDVPPLYEFHVFKDLFIDKLKKIEYPKAAGSYVSTAKGENFILNYDKSSGILTLLIHKDKGNPSILKVNFDGEELTCVIVDDMVTFELNDIYVNIEYLVNRIKIIR
>NC_014758.1|WP_013451725.1|1657304_1657940_-|hypothetical-protein
MDNIVAFLKNPNGHNEDGYNQLYNLFCRIAEKFDIEDTLEEFHNFLLFKLFNNASLTRFLMEVEEKQVIMSFVRKMIINHLFTMFKNKKDDISIFDNLTGDANDDSDLTIGDTIKDSSLAAEIIFEAYELLRLVRDQFSDKKLRILCHYFYSGEYVFIEDMNQNAFYKSVERIKKDLTDICLSNRFSEEAVSYFIQEIYLSEICEKFRINM
>NC_014758.1|WP_013451726.1|1657932_1658484_-|hypothetical-protein
MQLGQFIKFKQFSADHFLRKGDLILINVCVWKVLTGQAFANDLEKLKIRVDKQRPLVILKVVKNNAYYVALSTDDYAIRGAEVTFDLSRCDIGDRCKDFGFKKKAYIYVKEKKVKGRYGAKNILLSFTADLQKLSYLLEDSDTLNVISKYCQKRVDSIYDVFYFCANCDKEYIEKFSEGILNG
>NC_014758.1|WP_013451727.1|1658660_1659050_-|hypothetical-protein
MKIYLLFSHTLTDEQKSELEKMGVSDIIPIPEDLQFIWSNMPPAGELNITVLNEIIDWLSGSASEGDYILIQGDFGATYYMVNWAFKSGLIPIYATTERVVLEENKEGDRIVKKNIFRHVNFRRYVAFE
>NC_014758.1|WP_013451728.1|1659055_1660195_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MRVGHQLYYKVKYVPISPVHVGTGEEIDPLDYTIKNKVLYKINFVKFVENLSEHDKNQLLMHSKLPSVNSLMKVRTFINTIFDPSTMKDAIIESYPVDESIQARFSSRLSKFANEDPKNRQINELSIMEVYRNGLLPLIPGSSIKGAIRTAFLNHLLKDKDDRAREDILKNNFHGNKDPFDSLKVSDTYREKSDITVGFFINLPANLFAVDKIKGGLSVMAEVILPGKVYQGDIRFIADGRLFVKNENRYFSILRNMISNIESLFRICNEHYFPIFEKEYNMIKKENSENNFIKRVDYEKNNYLEQIRNNKVGLIRVGRHSGFEAVSIKGSKVKIKTKNGYDMRDASTTSWYCSFSDSGEPKNTNNVLPCGWMILKKDE
>NC_014758.1|WP_013451729.1|1660191_1661124_-|crispr-associated-protein,-csm4-family
MEYYKIRLKPKSSFGTLPMSDTIFGQMVWTLRRMGFDVDKMLENYLEEPFLVVSDFLLDDCGIVPKIPARYSVGKSKEDKLDMLLNRKSLKQKGYIPISTIIKEPTLTREKIVDKSRSIGNQHYQTSDVVRCSTNRLTSTTGDGFSPYTVIEHFYNGIDFSFYFFCSDDLKEYVLKALEIIGEIGFGKDASVGKGKFDVIVGSCEKVSVEKERANAVYTLSNCYLQGIDARNAYYEPFTRFGKHGDILAITGNPFKNPVVMARQGALIVFGEQLPSKCYIGKGIKSLSFHQETVMQGYSLYIPVYLEEDL
>NC_014758.1|WP_013451730.1|1661131_1661809_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MSTFKITKITGKLTLESGLHIGSGDTEMHIGGVDNQVIKDPITGEPYIPGSSLKGKIRSLLEYYAGSHVKTDGRPLSASKASTDLEKHIVTLFGSSGSDDRNAEFGVSRLVFSDTYLNKESRQSIMQTYGKFTEVKAENSINRLKGTAENPRFTERVIKGAVFDFAVSMRIFPKDNYDQLMEVFLTGLKLLTFDALGGSGSRGYGKVSIKFDKEDLQEKFDKITF
>NC_014758.1|WP_013451731.1|1661827_1662295_-|type-III-A-CRISPR-associated-protein-Csm2
MNKPNNSKFTQGSPNPQGQKNYSVDESVKKSFKEFDLKSLYSSQAEKVAKVIHQESSGKFNKNSQIRKFYDELYNLKMKVELSKDVEAEFSKVLPIVYLLGSKSAYARGRDKIGDNFFNFLKSNVMKIESFEDLKTFLLYFEAVLGYYKFLNPKE
>NC_014758.1|WP_013451732.1|1662291_1664670_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MNDQLLKTSLIGLAAFYHDIGKVYQRTGRHLTDKYGKGSYERQLLLNDDTHLHSLHTAYFIENNILNTPIDGLWKSTFNAPGFLFTSAAHHKPNNEILSKIVTMADQIASGLDREQYAERDRKRSQFDYRKVMMTPLLRIASLFEENDYSYRYPLSIVNLESIFPVKSEKLKDISAEENYKKIVEFFEENLNKIDYKLNFYVDGLISLFEEAFSFVPASTLGEFDDVSLYDHSRTTAAFATSLFKFYENNQRLPEYDEKAFLMIRGEFFGIQKFIFSEGAESGKNPAKILRGRSFYVSLMTEVAALMMSNKLNLPSFNLLLNAAGMFVILSDNSKETKDGIQEVNKVINDWLFEKFFGEVYFGIAYVEATPSDFSEKHYESLWLDLLTEMDKVKYSRFNLLTRDSIFENYHKQFDNAVSCSLCGRESAEKGAEYGKNCDELIKIGEQLVRKELKYLVLYRKDGGKIFNKYDYEFRSDVGDALLDASKIIDISLFDGFKGFYKSKINTYVATDNYVIKSFEEIAKGERGIDALGVFKADVDNLGALFALGLEKKRNVGENKRLTFSRISQLSRMINNFFAYYLPYKLKKDYPNTYTVFAGGDDLFLVGRYNDIFKLALELSQDFKRYTGYNNEVTISGGISIFKPNTPIAFMAEVVENNLTHSKKTNDYKKPKGYLTFLGAKAKWEDFIKVYEEVKKNSWLVPEATSFDYKLLELIEMSILLKNKNLNMQDLAKNIMWIPRLKYLLARQIKNQNAREELSLFLLDKINTAPELFKAISMFEIYNKRKKKGGKK

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Crispr_ID: NC_014758_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014758_2

1990498-1990853

Unclear

Consensus_repeat	Method
GTTTCATCTGAACCATGTGGGATTTAAAG	PILER-CR
GTTTCATCTGAACCATGTGGGATTTAAAG	CRISPRCasFinder
GTTTCATCTGAACCATGTGGGATTTAAAG	CRT

5 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas6

The CRISPR arrays of NC_014758_2

>merge|NC_014758|2|1990498-1990853|PILER-CR,CRISPRCasFinder,CRT
GTTTCATCTGAACCATGTGGGATTTAAAGTGCTCTGTCGTACAAATTTAGGAGTGGCAGAGGATCGGTTTCATCTGAACCATGTGGGATTTAAAGTTAAAGCTTGCGACAGAGATCTTAACAAGCTCTTTTTGTTTCATCTGAACCATGTGGGATTTAAAGCTAAAACTGTAGTTTTCCCCGTTCCTGCATACCCCTGTTTCATCTGAACCATGTGGGATTTAAAGATATTTTTTGTGTAAAAAAAAATTGATGTCAAAAGCGTTTCATCTGAACCATGTGGGATTTAAAGCGAGCTACAAAAACTACAACAAAATCGCTACAAGATGTTTCATCTGAACCATGTGGGATTTAAAG

>NC_014758|2|2|1990498-1990853|PILER-CR
GTTTCATCTGAACCATGTGGGATTTAAAG	TGCTCTGTCGTACAAATTTAGGAGTGGCAGAGGATCG
GTTTCATCTGAACCATGTGGGATTTAAAG	TTAAAGCTTGCGACAGAGATCTTAACAAGCTCTTTTT
GTTTCATCTGAACCATGTGGGATTTAAAG	CTAAAACTGTAGTTTTCCCCGTTCCTGCATACCCCT
GTTTCATCTGAACCATGTGGGATTTAAAG	ATATTTTTTGTGTAAAAAAAAATTGATGTCAAAAGC
GTTTCATCTGAACCATGTGGGATTTAAAG	CGAGCTACAAAAACTACAACAAAATCGCTACAAGAT
GTTTCATCTGAACCATGTGGGATTTAAAG

>NC_014758|2|2|1990498-1990853|CRISPRCasFinder
GTTTCATCTGAACCATGTGGGATTTAAAG	TGCTCTGTCGTACAAATTTAGGAGTGGCAGAGGATCG
GTTTCATCTGAACCATGTGGGATTTAAAG	TTAAAGCTTGCGACAGAGATCTTAACAAGCTCTTTTT
GTTTCATCTGAACCATGTGGGATTTAAAG	CTAAAACTGTAGTTTTCCCCGTTCCTGCATACCCCT
GTTTCATCTGAACCATGTGGGATTTAAAG	ATATTTTTTGTGTAAAAAAAAATTGATGTCAAAAGC
GTTTCATCTGAACCATGTGGGATTTAAAG	CGAGCTACAAAAACTACAACAAAATCGCTACAAGAT
GTTTCATCTGAACCATGTGGGATTTAAAG

>NC_014758|2|2|1990498-1990853|CRT
GTTTCATCTGAACCATGTGGGATTTAAAG	TGCTCTGTCGTACAAATTTAGGAGTGGCAGAGGATCG
GTTTCATCTGAACCATGTGGGATTTAAAG	TTAAAGCTTGCGACAGAGATCTTAACAAGCTCTTTTT
GTTTCATCTGAACCATGTGGGATTTAAAG	CTAAAACTGTAGTTTTCCCCGTTCCTGCATACCCCT
GTTTCATCTGAACCATGTGGGATTTAAAG	ATATTTTTTGTGTAAAAAAAAATTGATGTCAAAAGC
GTTTCATCTGAACCATGTGGGATTTAAAG	CGAGCTACAAAAACTACAACAAAATCGCTACAAGAT
GTTTCATCTGAACCATGTGGGATTTAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014758.1\|WP_013450328.1\|1987495_1988602_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_014758.1\|WP_148223201.1\|1984761_1987080_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NC_014758.1\|WP_013452028.1\|1984115_1984790_+\|CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
NC_014758.1\|WP_013452030.1\|1988928_1989909_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_014758.1\|WP_013452025.1\|1980414_1981209_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NC_014758.1\|WP_013452031.1\|1989924_1990188_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_014758.1\|WP_013452027.1\|1982678_1984094_+\|DevR-family-CRISPR-associated-autoregulator	cas7	pfam01905_cas7_CAS-I	gnl\|CDD\|376656
NC_014758.1\|WP_049770133.1\|1988594_1988912_+\|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_014758.1\|WP_013452040.1\|1996749_1997091_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013452036.1\|1994458_1995046_-\|aminotransferase-class-IV	unknown	unknown	gnl\|CDD\|235934
NC_014758.1\|WP_013452039.1\|1996201_1996750_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239516
NC_014758.1\|WP_013452037.1\|1995029_1995998_-\|aminodeoxychorismate-synthase-component-I	unknown	unknown	gnl\|CDD\|235932
NC_014758.1\|WP_041723936.1\|1991641_1991830_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013452034.1\|1991846_1992218_+\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_083797414.1\|1990886_1991282_+\|phage-major-tail-tube-protein	unknown	unknown	gnl\|CDD\|377436
NC_014758.1\|WP_083797391.1\|1987131_1987410_+\|Dna2/Cas4-domain-containing-protein	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_014758.1\|WP_013452026.1\|1981201_1982665_+\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013452038.1\|1995999_1996209_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274898
NC_014758.1\|WP_013452035.1\|1992682_1994221_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|313108
NC_014758.1\|WP_013452032.1\|1991287_1991548_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014758.1\|WP_013450328.1\|1987495_1988602_+\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	3.13686e-70
NC_014758.1\|WP_148223201.1\|1984761_1987080_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	6.2642e-60
NC_014758.1\|WP_013452028.1\|1984115_1984790_+\|CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.62043e-10
NC_014758.1\|WP_013452030.1\|1988928_1989909_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.38059e-173
NC_014758.1\|WP_013452025.1\|1980414_1981209_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	8.955e-25
NC_014758.1\|WP_013452031.1\|1989924_1990188_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.39007e-25
NC_014758.1\|WP_013452027.1\|1982678_1984094_+\|DevR-family-CRISPR-associated-autoregulator	gnl\|CDD\|376656	pfam01905, DevR, CRISPR-associated negative auto-regulator DevR/Csa2. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers. This family used to be known as DUF73. DevR appears to be negative auto-regulator within the system.	1.81006e-13
NC_014758.1\|WP_049770133.1\|1988594_1988912_+\|Dna2/Cas4-domain-containing-protein	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.80555e-35
NC_014758.1\|WP_013452036.1\|1994458_1995046_-\|aminotransferase-class-IV	gnl\|CDD\|235934	PRK07101, PRK07101, hypothetical protein; Provisional.	1.24457e-56
NC_014758.1\|WP_013452039.1\|1996201_1996750_-\|NUDIX-hydrolase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	2.93052e-43
NC_014758.1\|WP_013452037.1\|1995029_1995998_-\|aminodeoxychorismate-synthase-component-I	gnl\|CDD\|235932	PRK07093, PRK07093, para-aminobenzoate synthase component I; Validated.	8.36628e-161
NC_014758.1\|WP_083797414.1\|1990886_1991282_+\|phage-major-tail-tube-protein	gnl\|CDD\|377436	pfam04985, Phage_tube, Phage tail tube protein FII. The major structural components of the contractile tail of bacteriophage P2 are proteins FI and FII, which are believed to be the tail sheath and tube proteins, respectively.	4.11508e-33
NC_014758.1\|WP_083797391.1\|1987131_1987410_+\|Dna2/Cas4-domain-containing-protein	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	9.90096e-20
NC_014758.1\|WP_013452035.1\|1992682_1994221_+\|ATP-binding-protein	gnl\|CDD\|313108	pfam09820, AAA-ATPase_like, Predicted AAA-ATPase. This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.	1.35999e-109
NC_014758.1\|WP_013452038.1\|1995999_1996209_-\|hypothetical-protein	gnl\|CDD\|274898	TIGR03980, conserved_hypothetical_protein, hybrid cluster protein-associated redox disulfide domain. Members of this protein family resemble the domain of unknown function DUF1858 described by pfam08984, but all members contain an apparent redox-active disulfide. In at least one member protein, a cysteine in the CXXC motif is substituted by a selenocysteine. Most member proteins consist of this domain only, but a few members are fused to or adjacent to members of the hybrid-cluster (prismane) family or the nitrite/sulfite reductase family. [Energy metabolism, Electron transport].	0.00184835

>NC_014758.1|WP_013452031.1|1989924_1990188_+|CRISPR-associated-endonuclease-Cas2
MYLIITYDIGEERVNKIRKILKKYFMWVQNSVFEGEITEGKLTQCKLELEKVIIKEADSIYFYRIENRLNYRKVVLGVEKDMTGNIL
>NC_014758.1|WP_013452030.1|1988928_1989909_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MARSYYVFTNGRIKRKENTVYIENETGDKKAIPIEDIDTIHLYGELDLNTKLVNFICQQGKTVHFYNYYGFYAGSLIPRERNISGDLVVKQVEHYLDPQKRFYIAYSFVEAALFHILRNLREYKDTDEYQHKIKNELSKAAESKSISELMGCEGRAREVYYQAFNVILKEGFSIDKREKRPPTNPVNALISFANSMIYTTVLSEIYHTQLNPTISYLHEPRERRYSLCLDIAEIFKPLIADPIIFKLINNRIIKIEDFEEDVNYCYMNDTGRKKFIKELDQKLSTTIKHRKLKRNVSYKTLIRLECYKIIKHLIGDETYTPFKAWW
>NC_014758.1|WP_049770133.1|1988594_1988912_+|Dna2/Cas4-domain-containing-protein
MDKNASRVMVDTIKLTLPSNSIADADRIQLLYYLYYLKKLGIEKQGFINYPKMRKKEEVILTKEAEKEVELALIKIKEILNMEKPPELEKKSYCKKCAYYEFCFG
>NC_014758.1|WP_013450328.1|1987495_1988602_+|IS256-family-transposase
MDNIIINELSKYFKSMIQEIMLSEREKYLKEHSETRGNGYYIRTPKTILGNMELEIPRTRDGNFKPSIIPERKRVTFMLDDVIRALFTAGLSSRKTGEVIRNLMGTSVSASFVSSNLEISEEVISKFMNRELTENYPVIYIDATYISLKRDTVSKESVYVVLGLSTDGRREILTYCLPGGDEKSSVWRDIFINLTNRGLRGVKMVISDDLPGIGEVIKEVFPNADHQLCWFHLKKNIKNKVRKSDFDEILKELEYVFESKNEDEAKSRLQAFINKWSKLYRYFNNLRDKINSYCYFFKFHPKLRSYFSTTNWLERCFKELKDNIRIRGYFHSEESANKFLYLFFSDKSLKYNERKLKYSNIIEETLNG
>NC_014758.1|WP_083797391.1|1987131_1987410_+|Dna2/Cas4-domain-containing-protein
MNKEIEIDLDSLKTNGIKLNYLYVCERKLWLFDRGIQMEQNSDKVLMGKLLEENSYPKENKKKILIDNLINIDIVGENEIREVKYSNRVVYN
>NC_014758.1|WP_148223201.1|1984761_1987080_+|CRISPR-associated-helicase-Cas3'
MDIVMCGLIKEDEIEKCLAKSDKTTIETHNKSIYENLNILKERISINDDALLENLKKVIKYHDYGKANLKFQQKLEKRKSEEILFHHLISPLFYLISNSNSTLKDEDKINIYAIIRHHNRQLELIESLKLDFIDNSLRKALKAVFEDIKDLINIPKNDYDKYINAYLTALISSDYLKQKYFKNLVLTTGFLIRLDHAASGGLEVEEKPITEDRKELLKRALGITDFRPFQKKFGIERKQNYQAIVADTGMGKTGLSVLWSNRKKFYILPNRASVNAMYETLKHIYGENKVGLLHSTSLFNLLENYEDDMSVLKQFDQTRVLSKPVTVCTADQLFTAAFNMPGYEKIYATLSYSDVVIDEIQGFQPQQIIPMLKQIKETKELGTRYLIITATLPDIIAKRLNEYGFCVIDNDIDTVDNIKRHKIRIENKKIEDLSDEILQKFKTNKKILIVTNTVKKAQELYQSLLTNMLLTEKEKHRINILHSRFIWKDRQEKEKNVLDETKQDGDGVYINKDGCIWVCTQLVEASLDIDFDYLFTEAATADSLIQRMGRVWRHRKKDYKGDENIIIATDVEYKVYEKILVEKSVELIQEAIIENSNYLYSKNKREIVKILYSEEKLTEWGSKYLDEWKKFENAINSGWNFILEENAQKAFRDVMTIELIPSNFKDEVIDIYNSFKDFINQINSDANISDRGKKTQKRLEKLKKLKSIQEYKVPVPIYLVNPNVSSKKINCSKPIEWLDKDYAIGFLHENYEYNKVLGLTGKSLALEEDNIL
>NC_014758.1|WP_013452028.1|1984115_1984790_+|CRISPR-associated-protein-Cas5
MLRIEIYQQNACYRIPEIGNPILTFPLVPPSTIFGLLRYITSYSSINKYNTKIAISGIYESKIRHIITNHITGISDKGKYKSNIIPTEELFNVKHIIHIESNFENKINECIDKATRLGRMEDLINKIEIITSSEKKSNSCDLSEIKNLNYYIYVPFDKFESMNSLAIFNVPLDSDKDLLDKGFLKTYRVKLLFLRVQRLLLNQINQTKSDYCIDKDGYCYVWIN
>NC_014758.1|WP_013452027.1|1982678_1984094_+|DevR-family-CRISPR-associated-autoregulator
MSKKITFTNLIEAGVVNRNDSIGNISSVKKVSTHKGVKVIFSDKSYKRAIWERAAEKTDENGNFLWRRSEVSSVGGVTQKVSTIIDSEEFDFSGTMIAKPIPHNRESVLTTTYGISINEYKTFNEFLTNMALEKQLGTNKTNIYNRETFYGLYKVSGVIDLDRLGEQDILIPSKISEDDLELEAGMEVESFLEALYNGIFKGKDNEELTLDDWKETINSLIDVVEIEQNKKNDGYEIEIKGELAKLEINKNNKEEKTKNFISYLIDKLNKNGIRNEDIEKMIEEKLLKFITKIEIKDETLSINMKKNIEKEKAKINVPDNTWDIEKKLEWLHNIYSTYLKMKLDLETFKNLGKDRVENLTIEKSGNGYKVKISLKPEEKVRRLEVLIDTILNLYRTIEGRSETLSPLYTIWSTELTNPLYHTMIDEIIKSTNPLTLDECKIIKAHFGKQEKFEEIKNAIMNEVKEYYKSKK
>NC_014758.1|WP_013452026.1|1981201_1982665_+|hypothetical-protein
MSEKLTFTLTGNFQYDLGILGLKNVLDFFEIYYEYDDYSVSILLSEWNKIGNCSYFFGFYFNGIEQIKKKFKLKQNNLSITDFKKIILSAKVQPFNTSLESLIDFFNISQNKKIEFASYPALSIFNVSHLNVFNPGLLTKAKKDNQIDFFYNLYMQKFKGAKPSTDFNNKTCDFCQKYEGIPINRNNFIFASSAMNQGWYERPNIHICNYCSSLNLFSSYGLLKTGSGERYLIYSSNIKDLEKDNNILANSFEELITKYIENIKAETNAKDKFFIKIIFSGQNPDLDFLPFSTELLKFFIENKNLLEDLRNNDFVGIAKDPIIFSYKDTIKAILSGENLLYKADFIINCIIKQKSGNKNFKGFDDKAIKSALILLMLSIKLKKKEENSMIDKDLIEFIEFGENIRKRLYVGKNQNTARNKAISFSSAIRDSVNESKEKFMETLLQLSIYSQLPIPQNFLKKFNDPNFNYKEAGLAIALALMSIKDKE
>NC_014758.1|WP_013452025.1|1980414_1981209_+|CRISPR-associated-endoribonuclease-Cas6
MRFKILLRSDKLPLIYRHIFMSMIKEALKQSNPDYKDKLYPDKNFEKTKVAKPFTFSIMMPPGRKLETGTIDINGKTITDKIFYYPEGSYLSFLLSSSDYEFVMNLYNGLIKMKRFEYSSDIKFEYLKSMLLNEKDITENEITFKTLSPILVENKNEKPVLPIQESLQNFNDELNIIQDKIFKDVRGFGLKSRLNLTPLNIRKQVVKHTLRGFREKTGRDYMTLTCFEGTFKLQGSPEDLHLLYQTGIGLRTGQGFGMVEVASE
>NC_014758.1|WP_083797414.1|1990886_1991282_+|phage-major-tail-tube-protein
MGIYADSELPTGLDKLESKIKFNSVYPDFVALAADPFTSRTVIVRAPYQVWTQNGVSKTASLKAEMKGFFKEFDSAKFKKADSSEAEATMSVLYYKLEVDGVEVVEIDTLNNIYKVKGKDLMRDYVTAIGG
>NC_014758.1|WP_013452032.1|1991287_1991548_+|hypothetical-protein
MKEINLSDGRKATIQQGKGKDLFWAQRNASDPSDIIKLLMVRLVKIDGEQVTEDILDDLPIGDVMLLIREFSDSYSPLLVEKQSSA
>NC_014758.1|WP_041723936.1|1991641_1991830_-|hypothetical-protein
MEIIFSVLIGYILGGFVVFVIPIISIILLAYFLFRPIKACIKNQAKRIKLKKLLRERLKYLP
>NC_014758.1|WP_013452034.1|1991846_1992218_+|hypothetical-protein
MDYSIAIGLQLFDNFSRQLFTAKENFSKFSQDVEKTQKGLAKFGETMKKAFDVKAIREASEKVEDFSVKIAQATALPLAGMSKALKNFSEMENSRVEMEVAFMTKSGLPEEMEKINKTVEVFS
>NC_014758.1|WP_013452035.1|1992682_1994221_+|ATP-binding-protein
MKKLPIGIQNFREIIEDNYIYIDKTEEAYQLVSNYKYVFLSRPRRFGKSLFVDTLKELFEGNKKLFEGLYIYDKWNWDEKYPVIKISWAGDLQTLESVKLVALDIFKLNQEILGIICDNTTDPGSCFRDLIRKTYKKYGKKVVILIDEYDKPILDVIENVEQAKVNRGFLRSLYSIIKDNDAYIRFAFLTGVSKFSKASIFSGLNMLTDISLNPKFGNICGYTQRDIETSFKDYFVDVDMEKVKRWYNGYNFLKDNVYNPFDILQFISNGFLFRNYWFETGTPSFLIKLIKERNYFLPKLTNLIVDDKILSSFDIENIDLEVILFQSGYLTIEKVIQTPRSIGYKLRIPNLEVQISLNDYILRYLFNHREANYIQNQSYDAFYNGDLDVIRDNLTTLFSSIPYTNYTNNELKLYEGFYASVVYSYLASLGFDLIGEDVTNKGRIDLTVFASDKVYIIEFKVDGVKSEALKQIKEKRYYEKYFNDNKEIYLVGIEFSSSEKNIVNFEWEKLER
>NC_014758.1|WP_013452036.1|1994458_1995046_-|aminotransferase-class-IV
MYRVFETIKVVDGKPQNLFYHQKRINWTFHNYYKINPSFSIEKISAGLTFPDGINRLKIIYDPSNVEIQISPYNRKRVDYFYIVELDHLDYRFKYENRQILEQYCKADYGEPIFLINGFITDTTFSNLAFFDGHKWWTPSTYLLWGTKRELLIDSNKINVSEMRLSDLGCFKKFCLINSMNEVDEFSFRIDSIRY
>NC_014758.1|WP_013452037.1|1995029_1995998_-|aminodeoxychorismate-synthase-component-I
MFLSKDRFIDLFDTFYKNLTPFIFLVDFDVQNLFIAPLSSLEDKDGILFDFRGYTNSKGAVNDSTIYLKKEPVSLDSYRKSFDLVQKHLSDGDSYLLNLTFPTKIETDVSFGEIFQRSKALYKMKFYDEFVFFSPEQFVCIKDGKISTHPMKGTKVKVSESSEYELLNDEKELAEHITIVDLMRNDLSMVAKNVKVERFRYLSYIKSYGKTIIQTSSEISGDLTDGSVAEKLLNLLPAGSISGAPKRKTVEIIKKAELDNRGFYTGIAGVFDGLQIDSCVIIRYIEKKGDSLFYRSGGGITVYSKVEDEYREMIDKIYVPCI
>NC_014758.1|WP_013452038.1|1995999_1996209_-|hypothetical-protein
MGEKITFDTTIEEIVKSSGEAVKYLMEKKIRCIRCGEPIWGTLGEVLEEKGFSEEEKAKILDELNSLIT
>NC_014758.1|WP_013452039.1|1996201_1996750_-|NUDIX-hydrolase
MKDRWKFLDKKKIFSDNILDISHHHWEFTAKGVSTPFTSIDTNDWVVIIPELQNGKIALVRQFRPIVNEWTLEFPGGAINRGESHFDAAKRELEEETSLISDQLILLSTMRPNPAIMSNRCYVYLATNCKPDGRYNFDPFEDITVIDYTKSEVESLIRNGEITHSVVLGAYACYKLFGVSNG
>NC_014758.1|WP_013452040.1|1996749_1997091_-|hypothetical-protein
MSSYENVKFVKLSSGDTVIGIMDEENKKLNDVAMIQTIPTSAGMQIAILPFGFPYEDEIGGSIDASFIMYEYKKYPDEIVNKYLEAKSNIRITSSLDDLGGLGGKGGKGGLIL

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Crispr_ID: NC_014758_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014758_3

2109900-2111193

Orphan

Consensus_repeat	Method
GTCGCAATCCCTTAAAGTCAGGTCAATGATTCCAAC	PILER-CR
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CRISPRCasFinder
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CRT

17 spacers

The CRISPR arrays of NC_014758_3

>merge|NC_014758|3|2109900-2111193|PILER-CR,CRISPRCasFinder,CRT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGACAAAGAACCTATTTTTTTATTCATTACTTTTGCACTTTTGGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACACAGAAAGTGTATTTATCAATACACTCCCCGCAAAAATCGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACAGTAAACTAATTCCTCTTTGCTCGCCGTAAATGAAAGGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACATGCTTCAAACAGATTTGCTAAGAAACGAGCTTTTTTATGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACTCCTTCGTGGAAGGATTAACTCCATTTTTCATTTTCGTAGGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACAAAATTCAATAGCCTCTTCGCTCCATTTATAAAAACCCCGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACTCAATTCCTCTTTCTCTTCCTCACGCATTATCGTATTACGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACCAATTTTTTCTGGGGAGGCTTTAACCTTATGATTGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACAGAATTTATCCGTTCTTAATTCCCAGAGCTTTTGTATTGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACGCCCGTGGGAGAGTACGAAGTCTTGGCTTTGGAAGGGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACGTGTGTTTTGTAATTTTCCCACAATTTCTTGTGGGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACCAATGGAGGGGGAGCCAGACTTTATCTCCCTCCACTTCGAAGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACCCAGGGCTGCCCTTATATAACCCTCAGGGAGCTCCCGCTGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACTATTTTATTTTATTTTTATCTTCCTTCAAACTCCTCAATGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACGCTTGCAAGCTTGTATTTTGCATAACATTTGCCATCTCGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACCTTACAAAATTGTTGTTACTGAAACCAAGTTTTTTAGGTTGGAATCATTGACCTGACTTTAAGGGATTGCGACCTATCTATCAACTTAACTGCTTCATCGCCGTAATGTTTGTTGGAATCATTGACCTGACTTTGCGCAAGCAAGGA

>NC_014758|3|3|2109900-2111119|PILER-CR
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AAAGAACCTATTTTTTTATTCATTACTTTTGCACTTTTG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	ACAGAAAGTGTATTTATCAATACACTCCCCGCAAAAATC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AGTAAACTAATTCCTCTTTGCTCGCCGTAAATGAAAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	ATGCTTCAAACAGATTTGCTAAGAAACGAGCTTTTTTAT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TCCTTCGTGGAAGGATTAACTCCATTTTTCATTTTCGTAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AAAATTCAATAGCCTCTTCGCTCCATTTATAAAAACCCC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TCAATTCCTCTTTCTCTTCCTCACGCATTATCGTATTAC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CAATTTTTTCTGGGGAGGCTTTAACCTTATGATT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AGAATTTATCCGTTCTTAATTCCCAGAGCTTTTGTATT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GCCCGTGGGAGAGTACGAAGTCTTGGCTTTGGAAGG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GTGTGTTTTGTAATTTTCCCACAATTTCTTGTGG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CAATGGAGGGGGAGCCAGACTTTATCTCCCTCCACTTCGAA
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CCAGGGCTGCCCTTATATAACCCTCAGGGAGCTCCCGCT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TATTTTATTTTATTTTTATCTTCCTTCAAACTCCTCAAT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GCTTGCAAGCTTGTATTTTGCATAACATTTGCCATCTC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CTTACAAAATTGTTGTTACTGAAACCAAGTTTTTTAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC

>NC_014758|3|3|2109900-2111193|CRISPRCasFinder
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AAAGAACCTATTTTTTTATTCATTACTTTTGCACTTTTG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	ACAGAAAGTGTATTTATCAATACACTCCCCGCAAAAATC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AGTAAACTAATTCCTCTTTGCTCGCCGTAAATGAAAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	ATGCTTCAAACAGATTTGCTAAGAAACGAGCTTTTTTAT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TCCTTCGTGGAAGGATTAACTCCATTTTTCATTTTCGTAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AAAATTCAATAGCCTCTTCGCTCCATTTATAAAAACCCC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TCAATTCCTCTTTCTCTTCCTCACGCATTATCGTATTAC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CAATTTTTTCTGGGGAGGCTTTAACCTTATGATT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AGAATTTATCCGTTCTTAATTCCCAGAGCTTTTGTATT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GCCCGTGGGAGAGTACGAAGTCTTGGCTTTGGAAGG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GTGTGTTTTGTAATTTTCCCACAATTTCTTGTGG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CAATGGAGGGGGAGCCAGACTTTATCTCCCTCCACTTCGAA
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CCAGGGCTGCCCTTATATAACCCTCAGGGAGCTCCCGCT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TATTTTATTTTATTTTTATCTTCCTTCAAACTCCTCAAT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GCTTGCAAGCTTGTATTTTGCATAACATTTGCCATCTC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CTTACAAAATTGTTGTTACTGAAACCAAGTTTTTTAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CTATCTATCAACTTAACTGCTTCATCGCCGTAATGTTT
GTTGGAATCATTGACCTGACTTTGCGCAAGCAAGGA

>NC_014758|3|3|2109900-2111193|CRT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AAAGAACCTATTTTTTTATTCATTACTTTTGCACTTTTG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	ACAGAAAGTGTATTTATCAATACACTCCCCGCAAAAATC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AGTAAACTAATTCCTCTTTGCTCGCCGTAAATGAAAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	ATGCTTCAAACAGATTTGCTAAGAAACGAGCTTTTTTAT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TCCTTCGTGGAAGGATTAACTCCATTTTTCATTTTCGTAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AAAATTCAATAGCCTCTTCGCTCCATTTATAAAAACCCC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TCAATTCCTCTTTCTCTTCCTCACGCATTATCGTATTAC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CAATTTTTTCTGGGGAGGCTTTAACCTTATGATT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	AGAATTTATCCGTTCTTAATTCCCAGAGCTTTTGTATT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GCCCGTGGGAGAGTACGAAGTCTTGGCTTTGGAAGG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GTGTGTTTTGTAATTTTCCCACAATTTCTTGTGG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CAATGGAGGGGGAGCCAGACTTTATCTCCCTCCACTTCGAA
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CCAGGGCTGCCCTTATATAACCCTCAGGGAGCTCCCGCT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	TATTTTATTTTATTTTTATCTTCCTTCAAACTCCTCAAT
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	GCTTGCAAGCTTGTATTTTGCATAACATTTGCCATCTC
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CTTACAAAATTGTTGTTACTGAAACCAAGTTTTTTAG
GTTGGAATCATTGACCTGACTTTAAGGGATTGCGAC	CTATCTATCAACTTAACTGCTTCATCGCCGTAATGTTT
GTTGGAATCATTGACCTGACTTTGCGCAAGCAAGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014758.1\|WP_013452123.1\|2095966_2097574_-\|BREX-system-Lon-protease-like-protein-BrxL	unknown	unknown	gnl\|CDD\|379127
NC_014758.1\|WP_171789059.1\|2113551_2113692_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013452138.1\|2120783_2121098_+\|50S-ribosomal-protein-L21	unknown	unknown	gnl\|CDD\|235510
NC_014758.1\|WP_013452133.1\|2114508_2116134_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_014758.1\|WP_013452127.1\|2102474_2104214_-\|BREX-1-system-adenine-specific-DNA-methyltransferase-PglX	unknown	unknown	gnl\|CDD\|380294
NC_014758.1\|WP_013452122.1\|2095518_2095998_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013452134.1\|2116149_2116443_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NC_014758.1\|WP_013452121.1\|2093727_2095275_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|313108
NC_014758.1\|WP_013452126.1\|2101981_2102482_-\|hypothetical-protein	unknown	unknown	unknown
NC_014758.1\|WP_013452124.1\|2097585_2100090_-\|BREX-1-system-phosphatase-PglZ-type-A	unknown	unknown	gnl\|CDD\|274259
NC_014758.1\|WP_013452129.1\|2107698_2108289_-\|DUF1788-domain-containing-protein	unknown	unknown	gnl\|CDD\|378040
NC_014758.1\|WP_013452132.1\|2113860_2114478_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372439
NC_014758.1\|WP_013452130.1\|2108293_2108863_-\|DUF1819-family-protein	unknown	unknown	gnl\|CDD\|378066
NC_014758.1\|WP_013452135.1\|2116665_2118057_+\|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl\|CDD\|235490
NC_014758.1\|WP_013452136.1\|2118070_2118673_+\|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl\|CDD\|179314
NC_014758.1\|WP_013452128.1\|2104216_2107702_-\|BREX-system-P-loop-protein-BrxC	unknown	unknown	gnl\|CDD\|380283
NC_014758.1\|WP_013452125.1\|2100094_2101972_-\|BREX-1-system-adenine-specific-DNA-methyltransferase-PglX	unknown	unknown	gnl\|CDD\|380294
NC_014758.1\|WP_013452131.1\|2111581_2113120_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|313108
NC_014758.1\|WP_013452137.1\|2118688_2119222_+\|YqhA-family-protein	unknown	unknown	gnl\|CDD\|377024
NC_014758.1\|WP_013450276.1\|2119373_2120687_+\|transposase	unknown	unknown	gnl\|CDD\|376573

Protein	Function_ID	Function_description	E-value
NC_014758.1\|WP_013452123.1\|2095966_2097574_-\|BREX-system-Lon-protease-like-protein-BrxL	gnl\|CDD\|379127	pfam13337, Lon_2, Putative ATP-dependent Lon protease. This is a family of proteins that are annotated as ATP-dependent Lon proteases.	0
NC_014758.1\|WP_013450276.1\|2119373_2120687_+\|transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	4.40508e-08
NC_014758.1\|WP_013452138.1\|2120783_2121098_+\|50S-ribosomal-protein-L21	gnl\|CDD\|235510	PRK05573, rplU, 50S ribosomal protein L21; Validated.	6.09504e-44
NC_014758.1\|WP_013452133.1\|2114508_2116134_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_014758.1\|WP_013452127.1\|2102474_2104214_-\|BREX-1-system-adenine-specific-DNA-methyltransferase-PglX	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	0
NC_014758.1\|WP_013452136.1\|2118070_2118673_+\|3-isopropylmalate-dehydratase-small-subunit	gnl\|CDD\|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	2.88954e-86
NC_014758.1\|WP_013452134.1\|2116149_2116443_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	6.06065e-54
NC_014758.1\|WP_013452121.1\|2093727_2095275_+\|ATP-binding-protein	gnl\|CDD\|313108	pfam09820, AAA-ATPase_like, Predicted AAA-ATPase. This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.	1.68669e-113
NC_014758.1\|WP_013452135.1\|2116665_2118057_+\|3-isopropylmalate-dehydratase-large-subunit	gnl\|CDD\|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NC_014758.1\|WP_013452124.1\|2097585_2100090_-\|BREX-1-system-phosphatase-PglZ-type-A	gnl\|CDD\|274259	TIGR02687, conserved_hypothetical_protein, TIGR02687 family protein. Members of this family are uncharacterized proteins sporadically distributed in bacteria and archaea, about 880 amino acids in length. This protein is repeatedly found upstream of another uncharacterized protein of about 470 amino acids in length, modeled by TIGR02688.	1.16955e-130
NC_014758.1\|WP_013452129.1\|2107698_2108289_-\|DUF1788-domain-containing-protein	gnl\|CDD\|378040	pfam08747, DUF1788, Domain of unknown function (DUF1788). Putative uncharacterized domain in proteins of length around 200 amino acids.	2.02801e-43
NC_014758.1\|WP_013452132.1\|2113860_2114478_+\|hypothetical-protein	gnl\|CDD\|372439	pfam13036, LpoB, Peptidoglycan-synthase activator LpoB. This is a family of Gram-negative bacterial outer membrane lipoproteins. LpoB is required for the function of the major peptidoglycan synthase enzyme PBP1B. It interacts with PBP1B protein via the UvrB-like non-catalytic domain on that protein. LpoB has a 54-aa-long flexible N-terminal stretch followed by a globular domain with similarity to the N-terminal domain of the prevalent periplasmic protein TolB. The long, flexible N-terminal region of LpoB enables it to span the periplasm and reach its docking site in PBP1B. Peptidoglycan is the essential polymer within the sacculus that surrounds the cytoplasmic membrane of bacteria.	3.25807e-06
NC_014758.1\|WP_013452130.1\|2108293_2108863_-\|DUF1819-family-protein	gnl\|CDD\|378066	pfam08849, DUF1819, Putative inner membrane protein (DUF1819). These proteins are functionally uncharacterized. Several are annotated as putative inner membrane proteins.	1.12241e-36
NC_014758.1\|WP_013452128.1\|2104216_2107702_-\|BREX-system-P-loop-protein-BrxC	gnl\|CDD\|380283	NF033441, BREX_BrxC, BREX system P-loop protein BrxC. BrxC is a P-loop-containing protein, and probable ATPase, from BREX (bacteriophage exclusion) systems of type 1.	0
NC_014758.1\|WP_013452125.1\|2100094_2101972_-\|BREX-1-system-adenine-specific-DNA-methyltransferase-PglX	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	0
NC_014758.1\|WP_013452131.1\|2111581_2113120_+\|ATP-binding-protein	gnl\|CDD\|313108	pfam09820, AAA-ATPase_like, Predicted AAA-ATPase. This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.	5.81351e-112
NC_014758.1\|WP_013452137.1\|2118688_2119222_+\|YqhA-family-protein	gnl\|CDD\|377024	pfam03350, UPF0114, Uncharacterized protein family, UPF0114.	1.93488e-28

>NC_014758.1|WP_013452130.1|2108293_2108863_-|DUF1819-family-protein
MPVLETLKLIELKKQGLSDKDIETEVLINNYLQKVRPSTIKRVFGEFKKRLSYMDKDFIDLITELPFESKKHLLFANILETYPIMLEFMTEVVSVKLENYDFILYVSDFFKFLNSKEGASIQSLSENTRRKVKQVTFKILEQAGIIDSVKNRKIIKPLLNDNIIRYYSNKKEILKGLLMNENEILANIG
>NC_014758.1|WP_013452129.1|2107698_2108289_-|DUF1788-domain-containing-protein
MGTNLTSKLNCLINILKDENYFRLEHIANEVPFYIFDYDPEAELDVRKTIKIISDSDQLKYRIEVVNIYDFIISYLQEKDFLEKIFEMEQKLSPEKFLTRLKSIIDPELIINKIVQLNDEKNPDVFILTGIGNSYPIIRIHQIINRLQEKVCNKVVIVMYPGTFDVNETEGKLILFNSLESKAFYRAFKICGGSLK
>NC_014758.1|WP_013452128.1|2104216_2107702_-|BREX-system-P-loop-protein-BrxC
MIIKNIFEKDIERPINGVVKVGQDDLNIIKTEVEEYIVTSEIKKYLDDFFTHYVETLGMQTDKIGIWISGFFGSGKSHLLKMLAYIIENPTIGDNLTAGEIIREKVKDDALLSANIKKAYQTPSDVILFNIDSMSDTADGGEESIPKVFRRVFYDKLGYFGRFPFIAEIERNLDKKGCYEKFKDKFKELTGFNWIDERKNFALHEKKIFEALAYCNNVTIEEAENYYNKTEDYFKSISISDFAEMVKEYVDQKNKELKTNNYRLLFMVDEVGQFIAQDTNKMLNLQTIVEELGVKCKGSVWVVVTSQEDVESIIGDLPKTSKNEFSKILGRFKRFSLSGSNTDEVIKKRILAKNVEAAEELKKLYDKYSSILKNQFTFTADTATFEKYKDENDFINTYPFIPYQFKLLQKVFEAIRTKGIAGKHLSHGERSMLNAFQEACKNIKDSELGYISPFYLFYDTIEGFMDSYVLLTIKNAETNSSLNSFDVNLLKLLFLIRYVGQIKSNIDNIVILMLEKIDQDKQSLKEKIKESLSKLEHEVLINKSGDTYNFLTNEERDIRQEIKRIPIDSDARSNFIYEIVFNEIYLDTKHKYTHYNNNYDLIRTVDNISKGNGKLEIKVVTQHYYETSDSNLAMESQQRRIVIRLNSSNDLERELKAYLQTDEYIRKHQVSTKESFSNIIRDTQKENDERRKRIKSIIENLLENADYFGLGNKLNLLKPVNFRNVLRDQLDEIVGHIYHKMYLITQNSIKTASEIKEALNKKRSIVIDITTNDSAENEIINFIRDISHLEGNVTLKKIYDRFTEEPYGWKLLDIQYVIAILVANEKIHLLYQNEKISSQFHSKLEELITKSSYQSVVYVTLPQTANEDEINKAKQIFQEVSDNIPEENSDDFLKQFKKYINDLVEDIKANLGSLSSDFIPKVIAEEYLEELVKIAKQSDKVDIIKGIINNEKNLPTWIEYLGKVKNFLSNQIDRYKEIREFINTYKDGIVHYDHKTANDLLSKCNEYIKSESPFHLTIALANEIDNVSNELKKKLESKKEACIDEIRKRYEYALQISKENNEKIDEKLDPLDKMIEQIKNELKIENVIAKHSTFTQKIDKIIEIIKNKPKDKNTPKRVKISSIIYPKIISSKEEIDSFVNELKEKLYKELQNNEKIEISGD
>NC_014758.1|WP_013452127.1|2102474_2104214_-|BREX-1-system-adenine-specific-DNA-methyltransferase-PglX
MDTGEIKKFAVRSRQLFVEQVKVKAALLGFSEKGITEYREVKNEVIVNERVYPRKQWKEIERIVKKGKNSYLNLIDEVAYTWFNRFVALKFMEENGYISHRFVKSSSEKWYPDVLNSPELTGILDKNEIIQLRLNNEYEKLYKKLLIAHCNNLNKAMPFIFEEIDDYTELLLSDLLLSSKSIIAHIDKGLPAEFWKDVEIIGWIYQFYISEKKDQVIGSKKAYKKEDIPAATQLFTPRWIVDYLVQNSVGRIWMESYPKSILKDRMKYYVESDVDVEKKFYLNLNPENLMIIDPACGSGHILIRVFDILMNIYREMGYSDLDAVRNIVEKNLYGLDIDKRAVQLACFAVMMKAREYGGSKVLSQKFDLNIYEIQEVDENLITSTEFIKGLSKEEDGELQEILSIFVEAKNFGSLITIPDRYIEKLDYYLDLLSKQLNDDFDLTRKYASKYYQILKIAKILGQKYDAMIANPPYMGNRFHNDILKKFLQNNYPESKSDLFAAFIERGFEFLKDGGFEAMITMQSWMFLSRYEKLRKKILKKYQIVNMVHLGTRAFPEIGGEVVQNTAFVIRNCNPGDILE
>NC_014758.1|WP_013452126.1|2101981_2102482_-|hypothetical-protein
MSNFREIFEQAKLELQVFEKNKELICKKVLPIIFIAQINDFKIDSIKLRGKNSNDNFSKDLKKFEENHKLKFIIAKSSNKIPLSVNNITNSINLISLISYNGLLKYQSLLKRLRNAFFHNNFNIKNNFIYLKDINIKNKNKPTMLGKMKLNAFEELIDILSKYIRN
>NC_014758.1|WP_013452125.1|2100094_2101972_-|BREX-1-system-adenine-specific-DNA-methyltransferase-PglX
MPTFIKLTDYNSSEEKEKGFFDPKNRYVAKQEDFGKIPGSPIAYWVSDRVKEIFEKSKKLGEIAEPRQGLITGDNDRFLKFWYEVDIYNIGFGFSNREEAKESGLKWFPYNKGGDFRKWYGNYEYVVNWKNDGNEIKNFIDNKGKQKSRPQNVSYYFREGLTWTALTSGPFNLRYSNKFIFDAKGPMLFSKIGNIKYLLSFTNCIVTNSFLRILAPTMDYNQGPVYKIPIIFPKSDSTKQKIEELTQECIDISKEDWDSRETSWDFRTNELVRIMNYEFLMLNESKKNNSKSKIQNLTLETIYNRYCEYWREKFFKLHSNEEELNRLFIDIYELQDELTPDVPLDEITILKEETKIVDGDLVFNKDAIVKQFISYAVGCMFGRYSLDHEGLHIADMGVSIEEANSKFNIQNSTFTIDDDNIIPVFEFDFFADDIVSRFKEFLKITFSEKTLYENLSFIADALGKKSSESDEDAIRRYFHKEFYVDHVRRYNKRPIYWMFSSNPKGAGAFNVLIYMHRYYPGIVAKIRTDYLHPYIDKIEFEKNRLQQSIDNDVLSGQTLKKAQNTIDKIEKYLIELREYDVKLKYYADKMIKIDLDDGVKVNYCKFQDILVVFDNKLCTESETEE
>NC_014758.1|WP_013452124.1|2097585_2100090_-|BREX-1-system-phosphatase-PglZ-type-A
MDIKEKLLDKFSKSRIVFWFDEEGSFEDELENISLEGINIHKVENNEFYLKYLIEKEKPTESFLLYYNRKQPKIEENWLADILLYSETFFADHKFLIKDELNIRFEKFDSLYKDFKAFFKNKKRINKLKTYLSDNPDYKELSLGMIATVINAEKNDLENILFKVFENGLDEEDNEALKQLEKYNLDSMFYIIIKDHFKIKKDEELTLLKLAFLFVCSYMVLTAPNLVSLNSIKEYFDLFEGKGLQVAGHFVEEWIYNSKYNDLYSTISQEVDNKTKISQKLKNLSLEDLANIYALENIENIILVKILNENLENNIDFYLDIIKKREQSFWWGSYKNNYLSLENYLRFEKTLLLMNLAADTVENLVLSYTKQLYLIDTYYRNFIFYYKNSNNDLIFDYYKKIENKYQNVMNFLNSKWDDLLTSDFIHNNPKNQSNFYHNHLDQHLQKSERICIIISDALRYEIGCELENKLYSSRDRFEVSMDYMVANIPTITAVGMASLLPNKKIEIKDDGTVLVDDKPATNLKMRQDLLKTFNDDSLALTEEEVNSCTTSQLRELFKGKNLIYIYQNMIDKIGDDYTSEGNVFDMVDQCLNSLEKVIKKLVSSGIINIIVTSDHGFIYQDSNVEEYQKIEFPFDKKNIVLNPRYVLGDSLISISGSHFFEKIDNDKIKRSNILIPKSTLRFKSTSGAGKRFLHGGVTLQELILPLVKIRYTKKQNKKIVDFEMISPTKNIITSNNPKFKFLQSEPVSNNVLPLKARFGIYDSKNNLLSNFGYINFDTSSEDVNERTKILTLQLKPISFSKDDVYKLKAYDEDNDVLIKEYDFKIHILISNEFF
>NC_014758.1|WP_013452123.1|2095966_2097574_-|BREX-system-Lon-protease-like-protein-BrxL
MDKLDKKISELFPGKIVSKELGQKLKTGYNAPNFVIEYLVGMYCATNDEEQIKDGMETVKDILTKHYVRADEIEKVKYLMREEGSYKVIDKAEVYLEEKEDKYFMRLKTMQLDKIQVKVDLIEKNPRLLTTGVWGIITLQYLRLEELINEKVNLFMPLENQECMSWLSNDNIKIISAIQDEVVNNKKIKYRPKNLEDPYLLEDFRPIQVPKVDLEEIFENRKEFSLEEWIDFIMRSCGLEPSYFNERQKFLFLYRLIPFVENNYNLIELGPRGTGKSFVYKEISPNAILISGGKTTVAQLFEWAGVIMRQNTLGLVNLWDVVGFDEISYNVFKNKESIQILKDYMESGSYSRGKNTRFADASMVFVGNIDEAIENIIKDKNKNLFQWIAQEMQDAAFLERIHCFIPGWEFPKMRPEFITKKSGFIVDYFAEFMRSMRKYNYTDKYEKYFKLKNASQRDSVAIKRTFSGLAKLLFPENEMTKEDIKKLLKYACECRKRVKYNLRRMLPHEYTTDFIGFTDIETGEEFEIFAEEEIR
>NC_014758.1|WP_013452122.1|2095518_2095998_-|hypothetical-protein
MKYSLKKKLDKIEAICNKLEEIEKQVNYHEERDEAVSINVILSIIDVTLKSFSEVLECYDDVSYFIQYLDEDYVYRYLSYVDMVKKEGEKLIYELTDIQEKIYDKNYIFSCLKWLSKAFNLFKTRFQIIKFLTKCESLFESINCDDKNYLLTLIDDLDS
>NC_014758.1|WP_013452121.1|2093727_2095275_+|ATP-binding-protein
MKKLPIGVSSLEKLIRENCYYVDKTYFVEKLVNSGSQFFLSRPRRFGKSLLVDTIKQAFLGNRELFKGLYLENNWDWEKKYPVIHIDFGGGVVQDAQDLKEWIIKQLKRHMITYNVSVEEQNNARFMFTDLIISLKEIYKNPVVVLVDEYDKPILDNIDDTERAIEIREVLKDFYSVLKASDQYLKLVFLTGVSRFSKVSIFSGLNQLQDITLSPAFATICGYTQSELETVFSDRLEGVDLEKLRYWYNGYSWLGDKVYNPFDILLFLSEKIFRPYWFETGTPTFLMEIILNNKVFLPKLEEIKASDEILANLDVDFLKIENLLFQSGYLTIKETKTLGLRTIYILTYPNFEVKMSFNNFFLSDILPVASDKEEVQNSIVEAIEENSLEKLKTALYSFFASIPNDWYRKNDLDSYEGFYASVVYALFTGSGLNTRSEDTTNLGKIDLTVLYQARAYIIEFKVVEKDSEGKALGQIKEKRYYEKYTDSCREINLIGIEFSREKRNIVYFEYETLER
>NC_014758.1|WP_013452131.1|2111581_2113120_+|ATP-binding-protein
MKKLPIGIQNFREIIEDKYIYIDKTEEAYQLVSNYKYVFLSRPRRFGKSLFVDTLKELFEGNKKLFEGLYIYDKWNWDEKYPVIKISWAGDLTTLEKVEDRAIDIFKTNQRLLGIECENNNNPSSCFNELIQKAYEKYNQKVVILIDEYDKPILDVIENVEQAKINRGFLRSLYSIIKDNDAYIRFAFLTGVSKFSKASIFSGLNMLTDISLNPKYGNICGYTQRDLETSFKDYFVDVDMEKVKRWYNGYNFLKDNVYNPFDILQFISNGLVFDNYWFETGTPSFLIKLLKERRYFLPNFSNIVVDKKLLSSFDVEEIDIEVLLYQSGYLTIEKMIQNELLQSIEYKLKIPNIEVQISLNDYIINYLFKTDTRIKDPLIKSLYYGKPEELRDTLMALFASIPYNNYTNNELKLYEGFYASVVYSYLASLGVDLIGEDVTNKGRIDLTVFVSDKVYIMEFKVDGEKGEALSQIKHKNYAQKYLDSGKAIYLVGVEFSSSERNIVNFEWEKLER
>NC_014758.1|WP_171789059.1|2113551_2113692_-|hypothetical-protein
MGKDKIRNIILIPRKLDTNGGRGYKLKRQRDPYIFKMKESGIIPLL
>NC_014758.1|WP_013452132.1|2113860_2114478_+|hypothetical-protein
MRNLLLILLLFFLGCAESINKVNVSDNFKIHNSATLAILNFKTTGLPSNIGEKVAEKFSVEIVQTKKFKIIDRSNINKIFEEIGFQGNLDTLGGLDEKSKIKIRQLGAQYFMSGTVFSFEEKRRYDDNLVLFSKVHITAKIINIETGEVVWGAERMKDSKALNAGDRKPKSLMKVEIAAKSADKLLDEIISEMTENILKQLKNDK
>NC_014758.1|WP_013452133.1|2114508_2116134_-|chaperonin-GroEL
MAKAITFSEEARQAILRGVDKLANAVKVTLGPKGRNVVIEKKFGSPLVTKDGVTVAKEIELKDALENLGAQMVKEVASKTSDIAGDGTTTATVLAQAIYREGIKNVVAGSNPMDLKRGIDKAVEAVVAELKKMSKPIQGKKEIAQVGTISANNDPEIGNIIADAMERVGKDGVITIEENKSTDTVLDVVEGMQFDRGYLSPYFVTDPENMEAILENPYLLICDKKISNMKELLPILEQLAKQNAPFLIIAEDIEGEALATLVVNKLRGTLNCCAVKAPGFGDRRKEMLKDIAILTGGQVISEELGLKLENAKLSDLGRAKKVVVEKENTTIVEGAGKTEDIQARVNVIKKQIEETTSDYDREKLQERLAKLVGGVAVIKVGAATETEMKEKKARVEDALHATKAAVEEGIVPGGGVALLRASRAIANLKDLTPDQKVGADIVRRALEYPVRQIASNAGFEGSIVVNKILEAEKDTFGFDAHAEIYTDMIEAGIIDPTKVTRSALQNAASVAGLMLTTEAMITEIPEKKEPAMPNPGMGMDM
>NC_014758.1|WP_013452134.1|2116149_2116443_-|co-chaperone-GroES
MASIKPLQDRVLVKRLEAEEKTASGIIIPDTAKEKPQEGEVIATGPGKVLENGTRIELTVKPGDKILFSKYAGTEVKIDGTEYLIMREDDILGIINK
>NC_014758.1|WP_013452135.1|2116665_2118057_+|3-isopropylmalate-dehydratase-large-subunit
MGKNLFNKVWQLHEVAKLPGGRTQLFIGLHLIHEVTSPQAFSMLRELGLKVLFPERTFATCDHIIPTDDIKRPFADPLAEEMMQAIEKNTKEFGIKFFSPETGYQGVVHIVGPELGLTQPGITVACGDSHTATHGAFGAIAFGIGTSQVRDVLATQTMALNSFKVRKIDLKGSLSKGVYSKDIILHIIRKLGVNGGIGYAYEFAGEVIKGLSMEARMTICNMAIEGGARVGYINPDETTYEYLKGKPYAPKGADWDERIKYWESIKSDPDAEYDDVVEIDISSLEPMVTWGINPEQCIGISESIPEDNSDSVREALEYMKFKPGQKIKGTKIDVVFIGSCTNGRLEDLREAAMFLKGHKVAKGVKAIVVPGSYTIKKQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNPDKLVGDQISVSTSNRNFKGRQGSSTGRTILASPLTAAASAIAGAVADPREIFSIK
>NC_014758.1|WP_013452136.1|2118070_2118673_+|3-isopropylmalate-dehydratase-small-subunit
MGIDPIKIVKGRIIPILGDDIDTDRIIPARYLKCVTFDGIGEFAFYDERFENDGTPKNHPMNDPKYKGANIILSGNNFGCGSSREHAPQSIKRAGFQAIIAESFAEIFYGNSLTLGIVCATLPKEKIKEIAEIVAKNPSIECTIDVENKILVVGNNSYSIDIKESARKAFIDGTYDSLGELLKNIDKIRDFEKGLKYRFL
>NC_014758.1|WP_013452137.1|2118688_2119222_+|YqhA-family-protein
MKKIEFFFEKLLWHSRLFLFFAVISSVFAAILLIFMGTLDIFILFKKVIYSMGDYSYYESIQKESLGKIIGAIDNYLISTVLFIFGIGLYELFISKIDLLEKDNKSSKILVIHSLDQLKDKIAKVVVMVLIVTFFKYSISQKDWDMVKLLILAAGTLLVSFSLYIINSKGGHDEEKQ
>NC_014758.1|WP_013450276.1|2119373_2120687_+|transposase
MIYEIAENVKRKILILTQNLNDYITRPQQKYMIEMVSGVFATKSLNLTSIAGYLNERCGVKHSLKRLQRNTFNYSTLLDISNAYNIDYAYNETKSDDRLIISIDGGDLTHDYGIGFELIGKVHDGSSNKVGYGYPLNHAVCYSPKSKRMFSLYIDVYSYKSSNFKSENAKTIEMLEKIGIRFKDKGLFVFDRGYDRGEILRYMLRNGLSFVIRSVGKRHLDYNGSRLSVLDICKDKINRRYKKGGISYGYAKCYYHGHAVTLISVRGNSSKNMLYFMSEGHISSSKEAYFRISSYFSRWKIEESYKFMKQQFGIEKCLVRRFESLRTLLGMVSFCWNVLSQIESDVMISKLLEDMAKREKYDNEDKKVCEFKYYRISDGIERVLRSYNGKIFHHRDKKYDCDYVMYFKIGYYLKFPEERKKIFGMGKMKRKKSLLVA
>NC_014758.1|WP_013452138.1|2120783_2121098_+|50S-ribosomal-protein-L21
MIAILKTGGKQYIVKAGDVLKVEKIEGEPGALVKLDTVLMVSDGSNVQVGAPTVQGAFVEAEIIEQTRGEKVIAFKRRPRHDFKKKIGHRQHLTKIKIKDIKVS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014758_1	1.3\|1652698\|34\|NC_014758\|CRISPRCasFinder,CRT,PILER-CR	1652698-1652731	34	NZ_CP012203	Alteromonas macleodii strain HOT1A3 plasmid pAM1A3, complete sequence	127335-127368	9	0.735
NC_014758_1	1.22\|1654109\|40\|NC_014758\|CRISPRCasFinder,CRT,PILER-CR	1654109-1654148	40	NZ_LT960785	Lactobacillus sakei isolate MFPB19 plasmid 2, complete sequence	42073-42112	10	0.75
NC_014758_1	1.22\|1654109\|40\|NC_014758\|CRISPRCasFinder,CRT,PILER-CR	1654109-1654148	40	NZ_CP023007	Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence	37515-37554	10	0.75
NC_014758_1	1.22\|1654109\|40\|NC_014758\|CRISPRCasFinder,CRT,PILER-CR	1654109-1654148	40	NZ_CP021926	Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-1, complete sequence	38925-38964	10	0.75
NC_014758_1	1.22\|1654109\|40\|NC_014758\|CRISPRCasFinder,CRT,PILER-CR	1654109-1654148	40	NZ_LT907984	Lactobacillus sakei subsp. sakei 23K plasmid pJ23A1, complete sequence	39181-39220	10	0.75
NC_014758_1	1.13\|1653440\|36\|NC_014758\|CRISPRCasFinder,CRT,PILER-CR	1653440-1653475	36	MK448995	Streptococcus phage Javan626, complete genome	39094-39129	11	0.694
NC_014758_1	1.22\|1654109\|40\|NC_014758\|CRISPRCasFinder,CRT,PILER-CR	1654109-1654148	40	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	334288-334327	11	0.725

1. spacer 1.3|1652698|34|NC_014758|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012203 (Alteromonas macleodii strain HOT1A3 plasmid pAM1A3, complete sequence) position: , mismatch: 9, identity: 0.735

gaggaagctatgaggctaaaagaagttttaaaaa	CRISPR spacer
gaggaagctaagcggctaaaagaagagtctgatg	Protospacer
********** * ************  *. .* .

2. spacer 1.22|1654109|40|NC_014758|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT960785 (Lactobacillus sakei isolate MFPB19 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.75

agaaaattagagaaagaaaaaataaaaaaagatatgatgg------	CRISPR spacer
agaaaattaaagaaagaaaaaagaaaa------atgacgagtaaaa	Protospacer
*********.************ ****      ****.*.

3. spacer 1.22|1654109|40|NC_014758|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023007 (Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence) position: , mismatch: 10, identity: 0.75

agaaaattagagaaagaaaaaataaaaaaagatatgatgg------	CRISPR spacer
agaaaattaaagaaagaaaaaagaaaa------atgacgagtaaaa	Protospacer
*********.************ ****      ****.*.

4. spacer 1.22|1654109|40|NC_014758|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021926 (Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-1, complete sequence) position: , mismatch: 10, identity: 0.75

agaaaattagagaaagaaaaaataaaaaaagatatgatgg------	CRISPR spacer
agaaaattaaagaaagaaaaaagaaaa------atgacgagtaaaa	Protospacer
*********.************ ****      ****.*.

5. spacer 1.22|1654109|40|NC_014758|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT907984 (Lactobacillus sakei subsp. sakei 23K plasmid pJ23A1, complete sequence) position: , mismatch: 10, identity: 0.75

agaaaattagagaaagaaaaaataaaaaaagatatgatgg------	CRISPR spacer
agaaaattaaagaaagaaaaaagaaaa------atgacgagtaaaa	Protospacer
*********.************ ****      ****.*.

6. spacer 1.13|1653440|36|NC_014758|CRISPRCasFinder,CRT,PILER-CR matches to MK448995 (Streptococcus phage Javan626, complete genome) position: , mismatch: 11, identity: 0.694

ttcattacatttttggaaaatagacaggggtttcac	CRISPR spacer
cgcattacagttttggaaaatagaaaggtaggataa	Protospacer
. ******* ************** *** .   .*

7. spacer 1.22|1654109|40|NC_014758|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 11, identity: 0.725

agaaaattagagaaagaaaaaataaaaaaagatatgatgg	CRISPR spacer
gtaaaattagagaaagaaataatagaaaaagaagaactat	Protospacer
. ***************** ****.******* . . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1238549 : 1246165

Escherichia_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013451298.1\|1238549_1239686_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	7.4e-34	30.9
WP_013451299.1\|1239818_1240919_-	glycosyltransferase	NA	NA	NA	NA
WP_013451300.1\|1240974_1242090_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.4e-79	45.3
WP_013451301.1\|1242094_1242991_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.8e-38	36.0
WP_013451302.1\|1242987_1243545_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	4.7e-42	46.9
WP_013451303.1\|1243546_1244413_-	glucose-1-phosphate thymidylyltransferase RfbA	A0A1D7XFC1	Escherichia_phage	4.3e-98	60.3
WP_013451304.1\|1244737_1246165_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	2.8e-38	27.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_014749

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_014749_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014749_1

33042-33395

TypeV

Consensus_repeat	Method
GTTTCATCTGAACCATGTGGGATTTAAA	PILER-CR
GTTTCATCTGAACCATGTGGGATTTAAA	CRISPRCasFinder
GTTTCATCTGAACCATGTGGGATTTAAA	CRT

5 spacers

cas14j

The CRISPR arrays of NC_014749_1

>merge|NC_014749|1|33042-33395|PILER-CR,CRISPRCasFinder,CRT
GTTTCATCTGAACCATGTGGGATTTAAAGGTTTCTTCCACTTTCTTTACTTCTTCTTGTATTTCAGTTTCATCTGAACCATGTGGGATTTAAAGTTAAATATTCAACACGTATGTCTTCAATAATGTTCGCGTTTCATCTGAACCATGTGGGATTTAAATCAGGGTACGTAAGGGCAGTTTTGGACGTGGGGTTGAGTTTCATCTGAACCATGTGGGATTTAAATTATGTCACCGGTGATCATCCAACTATGGGAGAAGCAAGTTTCATCTGAACCATGTGGGATTTAAAGTCGAAGAAAATGGATTTTAGAGAGGTTGGCAGAGAGTTTCATCTGAACCATGTGGGATTTTTA

>NC_014749|1|1|33042-33331|PILER-CR
GTTTCATCTGAACCATGTGGGATTTAAA	GGTTTCTTCCACTTTCTTTACTTCTTCTTGTATTTCA
GTTTCATCTGAACCATGTGGGATTTAAA	GTTAAATATTCAACACGTATGTCTTCAATAATGTTCGC
GTTTCATCTGAACCATGTGGGATTTAAA	TCAGGGTACGTAAGGGCAGTTTTGGACGTGGGGTTGA
GTTTCATCTGAACCATGTGGGATTTAAA	TTATGTCACCGGTGATCATCCAACTATGGGAGAAGCAA
GTTTCATCTGAACCATGTGGGATTTAAA

>NC_014749|1|1|33042-33395|CRISPRCasFinder
GTTTCATCTGAACCATGTGGGATTTAAA	GGTTTCTTCCACTTTCTTTACTTCTTCTTGTATTTCA
GTTTCATCTGAACCATGTGGGATTTAAA	GTTAAATATTCAACACGTATGTCTTCAATAATGTTCGC
GTTTCATCTGAACCATGTGGGATTTAAA	TCAGGGTACGTAAGGGCAGTTTTGGACGTGGGGTTGA
GTTTCATCTGAACCATGTGGGATTTAAA	TTATGTCACCGGTGATCATCCAACTATGGGAGAAGCAA
GTTTCATCTGAACCATGTGGGATTTAAA	GTCGAAGAAAATGGATTTTAGAGAGGTTGGCAGAGA
GTTTCATCTGAACCATGTGGGATTTTTA

>NC_014749|1|1|33042-33395|CRT
GTTTCATCTGAACCATGTGGGATTTAAA	GGTTTCTTCCACTTTCTTTACTTCTTCTTGTATTTCA
GTTTCATCTGAACCATGTGGGATTTAAA	GTTAAATATTCAACACGTATGTCTTCAATAATGTTCGC
GTTTCATCTGAACCATGTGGGATTTAAA	TCAGGGTACGTAAGGGCAGTTTTGGACGTGGGGTTGA
GTTTCATCTGAACCATGTGGGATTTAAA	TTATGTCACCGGTGATCATCCAACTATGGGAGAAGCAA
GTTTCATCTGAACCATGTGGGATTTAAA	GTCGAAGAAAATGGATTTTAGAGAGGTTGGCAGAGA
GTTTCATCTGAACCATGTGGGATTTTTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014749.1\|WP_013447295.1\|36642_36807_-\|hypothetical-protein	unknown	unknown	unknown
NC_014749.1\|WP_013447282.1\|25258_26230_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|319251
NC_014749.1\|WP_013447298.1\|39094_40642_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|313108
NC_014749.1\|WP_013447287.1\|30990_31239_+\|hypothetical-protein	unknown	unknown	unknown
NC_014749.1\|WP_171789068.1\|29016_29439_+\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
NC_014749.1\|WP_013447294.1\|36435_36624_-\|hypothetical-protein	unknown	unknown	unknown
NC_014749.1\|WP_013447293.1\|36016_36358_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|366154
NC_014749.1\|WP_013447279.1\|19933_20890_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|227308
NC_014749.1\|WP_013447281.1\|24211_24952_-\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|223861
NC_014749.1\|WP_013447291.1\|34104_34971_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NC_014749.1\|WP_013447297.1\|37427_38966_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|313108
NC_014749.1\|WP_013447284.1\|27131_28589_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223666
NC_014749.1\|WP_013447283.1\|26216_27122_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NC_014749.1\|WP_013447288.1\|31509_32616_+\|IS256-like-element-ISCni1-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_014749.1\|WP_013447299.1\|40868_41609_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|237896
NC_014749.1\|WP_013447292.1\|34986_35571_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|366837
NC_014749.1\|WP_013447290.1\|33538_33736_-\|hypothetical-protein	unknown	unknown	unknown
NC_014749.1\|WP_013447286.1\|29422_30631_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NC_014749.1\|WP_013447300.1\|41605_42457_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_014749.1\|WP_049770153.1\|22748_24029_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292

Protein	Function_ID	Function_description	E-value
NC_014749.1\|WP_013447297.1\|37427_38966_+\|ATP-binding-protein	gnl\|CDD\|313108	pfam09820, AAA-ATPase_like, Predicted AAA-ATPase. This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.	8.21247e-111
NC_014749.1\|WP_013447282.1\|25258_26230_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|319251	cd16393, SPO0J_N, Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member. Spo0J (stage 0 sporulation protein J) is a ParB family member, a critical component of the ParABS-type bacterial chromosome segregation system. The Spo0J N-terminal region acts in protein-protein interaction and is adjacent to the DNA-binding domain that binds to parS sites. Two Spo0J bind per parS site, and Spo0J interacts with neighbors via the N-terminal domain to form oligomers via an Arginine-rich patch (RRXR). This superfamily represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	1.39485e-21
NC_014749.1\|WP_013447292.1\|34986_35571_+\|HNH-endonuclease	gnl\|CDD\|366837	pfam01844, HNH, HNH endonuclease. His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.	5.622e-11
NC_014749.1\|WP_013447293.1\|36016_36358_-\|glycosyltransferase	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.73412e-08
NC_014749.1\|WP_171789068.1\|29016_29439_+\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.37646e-49
NC_014749.1\|WP_013447281.1\|24211_24952_-\|sel1-repeat-family-protein	gnl\|CDD\|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	1.44125e-51
NC_014749.1\|WP_013447291.1\|34104_34971_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	3.82478e-43
NC_014749.1\|WP_013447286.1\|29422_30631_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.32702e-54
NC_014749.1\|WP_013447284.1\|27131_28589_-\|ATP-binding-protein	gnl\|CDD\|223666	COG0593, DnaA, ATPase involved in DNA replication initiation [DNA replication, recombination, and repair].	7.30348e-14
NC_014749.1\|WP_013447283.1\|26216_27122_-\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	4.04013e-24
NC_014749.1\|WP_013447288.1\|31509_32616_+\|IS256-like-element-ISCni1-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	3.18025e-70
NC_014749.1\|WP_013447299.1\|40868_41609_-\|ABC-transporter-permease	gnl\|CDD\|237896	PRK15066, PRK15066, inner membrane transport permease; Provisional.	1.03164e-22
NC_014749.1\|WP_013447298.1\|39094_40642_+\|ATP-binding-protein	gnl\|CDD\|313108	pfam09820, AAA-ATPase_like, Predicted AAA-ATPase. This family contains many hypothetical bacterial proteins. This family was previously the N-terminal part of the Pfam DUF1703 (pfam08011) family before it was split into two. This region is predicted to be an AAA-ATPase domain.	1.82176e-114
NC_014749.1\|WP_013447279.1\|19933_20890_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|227308	COG4974, XerD, Site-specific recombinase XerD [DNA replication, recombination, and repair].	2.8281e-30
NC_014749.1\|WP_013447300.1\|41605_42457_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.51732e-93
NC_014749.1\|WP_049770153.1\|22748_24029_+\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	6.7e-76

>NC_014749.1|WP_013447288.1|31509_32616_+|IS256-like-element-ISCni1-family-transposase
MDNIIINELSKYFKSMIQEIMLSEREKYLKEHSETRGNGYYIRTPKTILGDMELEIPRTRDGNFKPSIIPERKRVTFMLDDVIRALFTAGLSSRKTGEVIRNLMGTSVSASFVSSNLEISEEVISKFMNRELTENYPVIYIDATYISLKRDTVSKESVYVVLGLSTDGRREILTYCLPGGDEKSSVWRDIFINLTNRGLRGVKMVISDDLPGIGEVIKEVFPNADHQLCWFHLKKNIKNKVRKSDFDEILKELEYVFESNNEDEAKSRLHAFINKWSKLYRYFNNLRDKINSYCYFFKFHPKLRSYFSTTNWLERCFKELKDNIRIRGYFHSEESANKFLYLFFSDKSLKYHERKLRYSNIIEETLNG
>NC_014749.1|WP_013447287.1|30990_31239_+|hypothetical-protein
MEKILFPLFVNIVIYCMAKKRYLLAISCKFKYEFLIVKYEFWGVKCEVLVVKTKNMASGVTFHSGGLDHGKFYFLSCESPWT
>NC_014749.1|WP_013447286.1|29422_30631_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MLKAYRYRIYPDKEQEEFFTKTFGACRFVWNKMLEEKLKFLDRKEKIPIITPANYKKEFLFLKEVDSLALANIQLQNEKAFRDYFRNPKHFKLPKFKNKKGKQSYTTNNVKVDFEKGLLFLPKIKSGIKACFHRTFTGKIKSATITKTKTGKYFVSILVEIEQQCNIQPPKNEVCGIDLGLKDFAIITNEKKETIKIPSPKHLVKAEKRLKRLQNQLSKKQKGSKNREKHRVRLSKLHEHVSAARNDFLHKLSFAIIRDNQTIVVEDLNVKGLSQSNLSKSVLDSSWGKFLNYLKYKAEWYGRTIIVVDKFYPSSKTCSVCNFINHRLTLKNRHWTCEECGTYHDRDINASVNLMFYGMKKVGMEQPEFTPVDCALAAELKQFRSTSHHRMKQEATTSISGW
>NC_014749.1|WP_171789068.1|29016_29439_+|IS200/IS605-family-transposase
MNKVKLDTNKHSVYLLYYHLVLVVKYRKKVIDDRISNRLKEIFEYIQPNYNITLIEWSHDEDHVHILFKATPTSSLAKFINAYKSASSRLIKKEFPKIKEKLWDKYFWSRSYCLLTSGGAPVDVIRKYIENQGKKNAKSV
>NC_014749.1|WP_013447284.1|27131_28589_-|ATP-binding-protein
MGDKMEFSEYIEYIQNEIKKDGETYNEKYGILFIIGILSTKFTLENKKIIATASSFIIEKLKNEKEKMMDLLKDVIIAYDIEDIIFQAEKIINTIKTEDGFIEKEYTLPKNIIISQADSFNTKYSFDNYLVDSTNHSAYMTMKSVAEGNYGGKIITLYGPTGVGKTHLVSAMLNAFSEKYEGKSAYYFVKSYWVELIKKYSSMRQLEIFLREINKADIIAIDDLSFICDTNRPVYIQLIYDLINLRVVKEKVTVITTPVQPDYIKLNKELADNATGSYFELNKNGDVVLGSPFVSRLKSNMIYISEPSFNLKLLFAKRVLKYSLQIDFEELNKTSQDILAIIIDSHRGDFRYINGIMNELLEKYTLHNNINSAIMELADNMGLKEKLKINNQNHRINYLVERMCEKFSIRLSEIQGRLKKGSELKIIRNAIIYVLNKYHDFSFQAISEVFKISKVSAHSGYGEFEEEIEKNNEKHKEVLDIIIRV
>NC_014749.1|WP_013447283.1|26216_27122_-|ParA-family-protein
MKTSIYIGNVKGGTGKTTLALMLGEYYRQIKNKKVLMIDLDYQQVNTCQYFAEQTLLADMRHKNLYTLLDYIINNINTVVDKYSETRMELEKKFLDSLIPFKYNDENDELQIDYNFAVIASDIEFGEISNKMSKTIPLSHLVFKVLLEIAYKYYDVIIIDTPPGVDFLPSQFALMSVENLLTVTDVGEFGLTGLNKMIATFKSSSLINKNLNFVGVVINKVKQNSYDNDFVAFVKESYGDYIIDTVLNDYVDYKQALLERKYILTDYKQVRGQKSIENAKKLLNEIDSRVKWIRWDGDEKR
>NC_014749.1|WP_013447282.1|25258_26230_-|ParB/RepB/Spo0J-family-partition-protein
MKKDNMFNKSRATNILSGDLYQTNMVKVPIDKIVADEQIRKKFDEKGIEELAESIKKYGLINPILVELDDKTQMFKIIAGERRYLACKKLGINKITVHVLGSRSENEKKIMQFEENVRREDLTLYEKSTAIFELMQDFLAEKVGIDKSIDNILSELIKINDGKSSLNLKVATIKEDIEKYFGMSLMSIIYLLYPLSFNIDHIKYMHEANIPITIFLLFISVKNDKEFIEECLDKYLEGKINAEKIKRLVSGKKDTNQKTEVKKRIRILQNIKTAVNNFEKLKRTLEDENIIIREKDKVRNEIERLKRYINEIELKLKEDDNVV
>NC_014749.1|WP_013447281.1|24211_24952_-|sel1-repeat-family-protein
MSKKLNFLLFGLIFLAICINSWAGLVEDGLKLLDQKKYKEAFQKFKKACDGGDAKGCFILGVMYDNGQGVRQDYSKAVEFYQKACDGGEALGCFNLGFMYYNGQGVGQDYSKAVEFYQKACDGGDAWGCYNLGVQYEKGQGVGQDNFKAVEFYQKACDGGYALGCNNLGVMYAKGQGVGQDYFKAAEFYQKACDGGEAKGCYNLGVMYYEGQGVRQDYFRAKELFGKACDMKLQKGCDAYKELNKK
>NC_014749.1|WP_049770153.1|22748_24029_+|ATP-binding-protein
MKDIFKRVIIDFIESSPKKVMARDYNIPLNSKKIVSLVGVRRSGKSSILFDMINRLREKLPIENIIYINFEDDRLYPLDLKSLDFLLEAYYELYPSKRDQKIYLFLDEIQAVQDWELYVRRIYDTLDVQIFITGSSAKLLSTDIATSLRGRTITYEIFPFSFKEYLRYKNIDVNLHSSKSLSFIKNALANYIINGGFAETIDEDEQISRKILSDYLELIVYKDIIDRYNIQNRSLLKVLNKYCFTNIATLVSFNKLYNEFKSQGYKLGKDTIFQYISHLEDAYAIFTLPIYRNSIKEEQRNPKKIYAIDNGFKKIYDYAISEDISKLYENVVYLHLRSQTKNIYYFKQKHEVDFYAKFHDKEMLINVSVDIKDQKTRQRELEGLKEAMEYFNLKQSYLITKDEESTEVIDSRKIYIIPLYKWLLLY
>NC_014749.1|WP_013447279.1|19933_20890_+|tyrosine-type-recombinase/integrase
MTPKPAENPIPILQKHKENFLNELKSQNYSKNTITAYSQEIDYFIEFFRGFQDDMEIIDINRPFIQQSLIFREENSKTGKIATNTKKMYLKALYQFFVYLTDAMNGIKDFTTLFSKIKIKAETRQKEYLNEVEIKRLLNYINVKKNKRMSFITCRNILLIKILLYTGMRASEVINIKLSDITTYEQDKNIIQIRIIGKGNKEGFCYIDHLKISEELEDTLLFRKRLNITSEYLFTTKTGRQMTRQEAFLATANILKKAGINKKGLHLFRHTLGFHLAQKGVRIEDIQEILRHSNINTTRIYVQRREADKINGIKKIDY
>NC_014749.1|WP_013447290.1|33538_33736_-|hypothetical-protein
MAVKKSKKSSNEQTSQEQAKEPQNEERITFCGSVLLTDSEIESLLQDLRMSYKILDMLESKQTQD
>NC_014749.1|WP_013447291.1|34104_34971_+|site-specific-DNA-methyltransferase
MLSKVYKCPNHTEYQSKNVNNEDIFNYLIEKLKAKTILHHKRAILLKGDVLNNNYFENDIFDLIVTSPPYNVDIKYNTHKDNISYEEYLQFSEAWLSNCYKWSKKQARLCLNIPLDKNKGGQRSVGADLTILAQKVGWKYHSTIIWNEGNISRRTAWGSWLSASAPYVIAPVELIVILYKEEWKKTQGTRISDISKDEFMQWTNGLWTFNGESKKRIGHPAPFPLELPYRCIKLFSFVQDIVFDPFAGSGTTLIAANNTNRYSIGLEIDSSYCELSKQRVLQESEMLF
>NC_014749.1|WP_013447292.1|34986_35571_+|HNH-endonuclease
MVKEKTITDLIIEFFKKHPKEDMPHGPVVDWVEEQYSKLYNRKPRDTWRSIRRLHQEGFLIKVKKGIYRYDPDLVADKHLEEFSQELKNQILKRDNYKCVICGRTAKEGYELHIDHILPKDKGGKATLDNGQTLCSICNFRKKNYNQTESGKRMFIRLLKIAKKIGDIETQKFCEEILKIYEKYNINGHIEWDD
>NC_014749.1|WP_013447293.1|36016_36358_-|glycosyltransferase
MFSCLIPAYNENNAVIEAICYKLLKYDIKEIIIIDDGSVNPVELTINSNLIKIIRKEKNSGKGNAIATDLKIKNNFFLSTMFIICRKKDQNFQRPCNLICVNPDSSIYKINHL
>NC_014749.1|WP_013447294.1|36435_36624_-|hypothetical-protein
MRHVNKNHFVEKLLEKRIERDGFYYTKKKLRLEQIIGIIGTFFMAICIPLFLYFVFSKINSF
>NC_014749.1|WP_013447295.1|36642_36807_-|hypothetical-protein
MENGEIKKRKIRPGSLEDIVEYKSKLELQAYKFTLFAIILGFVLGFLLFSIGKK
>NC_014749.1|WP_013447297.1|37427_38966_+|ATP-binding-protein
MKKLPIGIQTFSKIREEGYIYIDKTEEAFELVNNFTYVFLSRPRRFGKSLFLDTLKELFEGNKKLFEGLYIYDKWNWDEKYPVIKISWAGDLTTLERVEDRAIDIFKTNQRLLGIECENNKNPSSCFNELIQKAYEKYNQKVVILIDEYDKPILDVIENVEQAKINRGFLRNLYSIIKDNDAYIRFAFLTGVSKFSKASIFSGLNMLTDISLNPKYGNICGYTQRDIETSFKDYFVDVDMEKVKRWYNGYNFLKDNVYNPFDILQFISNGLVFDNYWFETGTPSFLIKLLKERRYFLPNFSNIVVDKKLLSSFDVENIDLEVILFQSGYLTIEKVIQTPRSIGYKLKIPNLEVQISLNDYILRYLFNYRESNDIQNQSYDAFYNGDLDVIRDNLTTLFSSIPYTNYTKNELKLYEGFYASVVYSYLASLGFDLIGEDVTNKGRIDLTVFVSDKVYIIEFKVDGVKGEALFQIKHKNYAQKYLDRGKDIYLVGIEFSSSERNIVNFEWEKLER
>NC_014749.1|WP_013447298.1|39094_40642_+|ATP-binding-protein
MKKLPIGISTLQSIREDNCYYVDKTPFVKKLVDNGKYYFLSRPRRFGKSLLVDTIKQAFLGNRELFKGLYLENNWDWEKKYPVIHIDFGGGVVQDAQDLKEWIIKQLKRHMITYNVSVEEQNNARFIFTDLIISLKEIYKNPVVVLVDEYDKPILDNIDDTEKAIEIREVLKDFYSVLKASDQYLKLVFLTGVSRFSKVSIFSGLNQLQDITLSPAFATICGYTQSELETVFSDRLEGVELEKLRYWYNGYSWLGDKVYNPFDVLLFLSEKIFRPYWFETGTPTFLMEIILNNKVFLPKLEEIKASDEILANLDVDFLKIENLLFQSGYLTIKETKKLGLKTIYILTYPNFEVKMSFNNFFLSDILPVASDKEEVQNSIVEAIEENSLENLKTALYSFFASIPNDWYRKNDLDSYEGFYASVVYALFTGSGLNTRSEDTTNLGKIDLTVLYQDRAYIIEFKVVEKDSEGKALGQIKEKRYYEKYTDSCREINLIGIEFSKEKRNVVYFEYETLER
>NC_014749.1|WP_013447299.1|40868_41609_-|ABC-transporter-permease
MINGFYGVYLRELLVLKSRLWKVILSSAISPLLFLLAFGYGVGRNSEINGFSYLSFLLPGLITMSSMNQAYGISTEINISRFYFKVFDEFLLAPIPKWQIILGEVFYGITKGLMPGFIVIFYSFIIGVKLSINFYFFISLMMHLITFSLLGFIIALVVKNHGDQFSFNTFFITPMIFLSGTFYPVDKMPSIIKYIAHIFPLTYSTHLIRSSLLLKTISTTDFCILLIMIIILSFIANKIVNKIETT
>NC_014749.1|WP_013447300.1|41605_42457_-|ABC-transporter-ATP-binding-protein
MQIKIINLMKKYGNSVALKNITFRIEDKTITALLGPNGAGKTTTINILAGLLKPDDGEIYYGDLDFLTNSNKIKSIIGLVPQYNNIDKDLTLYQNLLIHSILFGVKKNEIKNRIEEILNFTGLTNHKNKEAGKLSGGMKRRLVIGRAILHRPKILFLDEPTVGLDPATRRHIWDFVKNINKNFGCTVVLTTHYIEEAELLSDYVYFIDKGEIIKHGKPENLKNEMGKYALEIFIEGKTREEYFESKTEAIERLKQLTYVDMAKIREVNLEDVYLKLTGKKIDI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NC_014749_1	1.1\|33070\|37\|NC_014749\|PILER-CR,CRISPRCasFinder,CRT	33070-33106	37	NC_014749	Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence	33070-33106	1.0
NC_014749_1	1.2\|33135\|38\|NC_014749\|PILER-CR,CRISPRCasFinder,CRT	33135-33172	38	NC_014749	Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence	33135-33172	1.0
NC_014749_1	1.3\|33201\|37\|NC_014749\|PILER-CR,CRISPRCasFinder,CRT	33201-33237	37	NC_014749	Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence	33201-33237	1.0
NC_014749_1	1.4\|33266\|38\|NC_014749\|PILER-CR,CRISPRCasFinder,CRT	33266-33303	38	NC_014749	Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence	33266-33303	1.0
NC_014749_1	1.5\|33332\|36\|NC_014749\|CRISPRCasFinder,CRT	33332-33367	36	NC_014749	Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence	33332-33367	1.0

1. spacer 1.1|33070|37|NC_014749|PILER-CR,CRISPRCasFinder,CRT matches to NC_014749 (Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence) position: , mismatch: 0, identity: 1.0

ggtttcttccactttctttacttcttcttgtatttca	CRISPR spacer
ggtttcttccactttctttacttcttcttgtatttca	Protospacer
*************************************

2. spacer 1.2|33135|38|NC_014749|PILER-CR,CRISPRCasFinder,CRT matches to NC_014749 (Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence) position: , mismatch: 0, identity: 1.0

gttaaatattcaacacgtatgtcttcaataatgttcgc	CRISPR spacer
gttaaatattcaacacgtatgtcttcaataatgttcgc	Protospacer
**************************************

3. spacer 1.3|33201|37|NC_014749|PILER-CR,CRISPRCasFinder,CRT matches to NC_014749 (Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence) position: , mismatch: 0, identity: 1.0

tcagggtacgtaagggcagttttggacgtggggttga	CRISPR spacer
tcagggtacgtaagggcagttttggacgtggggttga	Protospacer
*************************************

4. spacer 1.4|33266|38|NC_014749|PILER-CR,CRISPRCasFinder,CRT matches to NC_014749 (Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence) position: , mismatch: 0, identity: 1.0

ttatgtcaccggtgatcatccaactatgggagaagcaa	CRISPR spacer
ttatgtcaccggtgatcatccaactatgggagaagcaa	Protospacer
**************************************

5. spacer 1.5|33332|36|NC_014749|CRISPRCasFinder,CRT matches to NC_014749 (Calditerrivibrio nitroreducens DSM 19672 plasmid pCALNI01, complete sequence) position: , mismatch: 0, identity: 1.0

gtcgaagaaaatggattttagagaggttggcagaga	CRISPR spacer
gtcgaagaaaatggattttagagaggttggcagaga	Protospacer
************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014758

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_014749

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection