CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP025395	Staphylococcus aureus O46 chromosome, complete genome	5 crisprs	cas3,DEDDh,DinG,csa3,WYL	2	0	9	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP025395_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025395_1

1814355-1814438

Orphan

Consensus_repeat	Method
GGGCCCCAACACAGAAGCTGGCCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025395_1

>merge|NZ_CP025395|1|1814355-1814438|CRISPRCasFinder
GGGCCCCAACACAGAAGCTGGCCAATAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAAGGGCCCCAACACAGAAACTGGCCAA

>NZ_CP025395|1|1|1814355-1814438|CRISPRCasFinder
GGGCCCCAACACAGAAGCTGGCCAA	TAGTCAGCTTTCAATAATGTGCAAGTTGGGGTAA
GGGCCCCAACACAGAAACTGGCCAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025395.1\|WP_000526536.1\|1830451_1831405_+\|TIGR01212-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224163
NZ_CP025395.1\|WP_000811165.1\|1806556_1806868_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP025395.1\|WP_000265407.1\|1812696_1814106_-\|Mn(2+)-dependent-dipeptidase-Sapep	unknown	unknown	gnl\|CDD\|235988
NZ_CP025395.1\|WP_000434769.1\|1810503_1811295_-\|phosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|223584
NZ_CP025395.1\|WP_001217116.1\|1815093_1815789_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP025395.1\|WP_000004344.1\|1815785_1817447_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_CP025395.1\|WP_000836469.1\|1826122_1826434_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NZ_CP025395.1\|WP_001025061.1\|1829160_1830342_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP025395.1\|WP_001266157.1\|1809844_1810489_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP025395.1\|WP_000764421.1\|1831401_1831965_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|377744
NZ_CP025395.1\|WP_001091387.1\|1805599_1806457_-\|DUF1444-domain-containing-protein	unknown	unknown	gnl\|CDD\|237463
NZ_CP025395.1\|WP_000163826.1\|1808095_1808407_+\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|227871
NZ_CP025395.1\|WP_001803813.1\|1826455_1828873_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_CP025395.1\|WP_001048371.1\|1804974_1805571_-\|DUF4479-domain-containing-protein	unknown	unknown	gnl\|CDD\|234804
NZ_CP025395.1\|WP_000118330.1\|1801129_1804954_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP025395.1\|WP_000284996.1\|1817853_1819122_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|367519
NZ_CP025395.1\|WP_000411088.1\|1811844_1812693_-\|D-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|130191
NZ_CP025395.1\|WP_001051855.1\|1814654_1815077_-\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|378938
NZ_CP025395.1\|WP_101305148.1\|1819238_1825796_-\|LPXTG-anchored-repetitive-surface-protein-SasC	unknown	unknown	gnl\|CDD\|275089
NZ_CP025395.1\|WP_001024574.1\|1806932_1808009_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906

Protein	Function_ID	Function_description	E-value
NZ_CP025395.1\|WP_000526536.1\|1830451_1831405_+\|TIGR01212-family-radical-SAM-protein	gnl\|CDD\|224163	COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].	0
NZ_CP025395.1\|WP_000811165.1\|1806556_1806868_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	1.82726e-24
NZ_CP025395.1\|WP_000265407.1\|1812696_1814106_-\|Mn(2+)-dependent-dipeptidase-Sapep	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
NZ_CP025395.1\|WP_000434769.1\|1810503_1811295_-\|phosphotransferase-family-protein	gnl\|CDD\|223584	COG0510, ycfN, Thiamine kinase and related kinases [Coenzyme transport and metabolism].	1.89607e-82
NZ_CP025395.1\|WP_001217116.1\|1815093_1815789_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	6.04755e-93
NZ_CP025395.1\|WP_000004344.1\|1815785_1817447_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.06974e-123
NZ_CP025395.1\|WP_000836469.1\|1826122_1826434_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	1.0608e-25
NZ_CP025395.1\|WP_001025061.1\|1829160_1830342_-\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.66072e-94
NZ_CP025395.1\|WP_001266157.1\|1809844_1810489_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.9831e-87
NZ_CP025395.1\|WP_000764421.1\|1831401_1831965_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	3.62052e-64
NZ_CP025395.1\|WP_001091387.1\|1805599_1806457_-\|DUF1444-domain-containing-protein	gnl\|CDD\|237463	PRK13668, PRK13668, hypothetical protein; Provisional.	2.02352e-168
NZ_CP025395.1\|WP_000163826.1\|1808095_1808407_+\|PepSY-domain-containing-protein	gnl\|CDD\|227871	COG5584, COG5584, Predicted small secreted protein [Function unknown].	4.78628e-46
NZ_CP025395.1\|WP_001803813.1\|1826455_1828873_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP025395.1\|WP_001048371.1\|1804974_1805571_-\|DUF4479-domain-containing-protein	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	6.56195e-48
NZ_CP025395.1\|WP_000118330.1\|1801129_1804954_-\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	0
NZ_CP025395.1\|WP_000284996.1\|1817853_1819122_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|367519	pfam03486, HI0933_like, HI0933-like protein.	0
NZ_CP025395.1\|WP_000411088.1\|1811844_1812693_-\|D-amino-acid-transaminase	gnl\|CDD\|130191	TIGR01121, D-alanine_aminotransferase, D-amino acid aminotransferase. This enzyme is a homodimer. The pyridoxal phosphate attachment site is the Lys at position 146 of the seed alignment, in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family; the family is designated equivalog, but with this caveat attached. [Energy metabolism, Amino acids and amines].	8.53229e-159
NZ_CP025395.1\|WP_001051855.1\|1814654_1815077_-\|YtxH-domain-containing-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	0.000469922
NZ_CP025395.1\|WP_101305148.1\|1819238_1825796_-\|LPXTG-anchored-repetitive-surface-protein-SasC	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.33904e-120
NZ_CP025395.1\|WP_001024574.1\|1806932_1808009_-\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	4.15596e-153

>NZ_CP025395.1|WP_000265407.1|1812696_1814106_-|Mn(2+)-dependent-dipeptidase-Sapep
MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQDKLAEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
>NZ_CP025395.1|WP_000411088.1|1811844_1812693_-|D-amino-acid-transaminase
MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAKDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKYIESHSI
>NZ_CP025395.1|WP_000434769.1|1810503_1811295_-|phosphotransferase-family-protein
MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAALSAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSMLKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHMPSLDSRFFTVVHGDVNHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNLNKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI
>NZ_CP025395.1|WP_001266157.1|1809844_1810489_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MRVRYKPWAEDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
>NZ_CP025395.1|WP_000163826.1|1808095_1808407_+|PepSY-domain-containing-protein
MTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKSYFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVER
>NZ_CP025395.1|WP_001024574.1|1806932_1808009_-|M42-family-metallopeptidase
MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFIENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQGQRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGDTIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGLRGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPAFRDYLLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYFAARSLLSEAICNLDNNQIETLQYK
>NZ_CP025395.1|WP_000811165.1|1806556_1806868_-|thioredoxin-family-protein
MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEERYPMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEQIDAFLAQYV
>NZ_CP025395.1|WP_001091387.1|1805599_1806457_-|DUF1444-domain-containing-protein
MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
>NZ_CP025395.1|WP_001048371.1|1804974_1805571_-|DUF4479-domain-containing-protein
MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVGYNIFEISKDITIEETGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKDKHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGVASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE
>NZ_CP025395.1|WP_000118330.1|1801129_1804954_-|DNA-translocase-FtsK
MSWFDKLFGEDNDSNDDLIHRKKKRRQESQNIDNDHDSLLPQNNDIYSRPRGKFRFPMSVAYENKNVEQSADTISDEKEQYHRDYRKQSHDSRSQKRHRRRRNQTTEEQNYSEQRGNSKISQQSIKYKDHSHYHTNKPGTYVSAINGIEKETHKSKTHNMYSNNTNHRANDSTPDYHKESFKTSEVPSAIFGTMKPKKLENGRIPVSKPSEKVESDKQKYDKYVAKTQTSQNKHLEQEKQNDSVVKQGTASKSSDENVSSTTKSMPNYSKVDNTIKIENIYASQIVEEIRRERERKVLQKRRFKKALQQKREEHKNEEQDAIQRAIDEMYAKQAERYVGDSSLNDDSDLTDNSTEASQLHTNGIENEAVSNDENKQASIQNEDTDDTHVDESPYNYEEVSLNQVSTTQQLSDDEVTVSDVTSQRQAALQHNVEVNNQDELKNQSRLIADSEEDGATNKEEYSGSQIDDAEFYELNDTEVDEDTTSNSEDNTNRDASEMHVDAPKTQEHAVTESQVNNIDKTVDNEIELAPRHKKDDQTNLSVNSLKTNDVNDGHVVEDSSMNEIEKQNAEITENVQNEAAESEQNVEEKTIENVNPKKQTEKVSTLSKRPFNVVMTPSDKKRMMDRKKHSKVNVPELKPVQSKQAVSESKTASQATPSSSTASQESNTNAYKTNNMTSNNVENNQLIGHAETENDYQNAQQYSEQKPSADSTQTEIFEESQDDNQLENEQVDQSTPSSVSEVSDITEESEETTHPNNTSGQQDNDDQQKDIQPSFSNQNEDTANENRPRTNQPDVATNQAVQTSKPMIRKGPNIKLPSVSLLEEPQVIEPDEDWITDKKKELNDALFYFNVPAEVQDVTEGPSVTRFELSVEKGVKVSRITALQDDIKMALAAKDIRIEAPIPGTSRVGIEVPNQNPTTVNLRFIIESPSFKNAESKLTVAMGYRINNEPLLMDIAKTPHALIAGATGSGKSVCINSILMSLLYKNHPEELRLLLIDPKMVELAPYNGLPHLVAPVITDVKAATQSLKWAVEEMERRYKLFAHYHVRNITAFNKKAPYDERMPKIVIVIDELADLMMMAPQEVEQSIARIAQKARACGIHMLVATQRPSVNVITGLIKANIPTRIAFMVSSSVDSRTILDSGGAERLLGYGDMLYLGSGMNKPIRVQGTFVSDDEIDDVVDFIKQQREPDYLFEEKELLKKTQTQSQDELFDDVCAFMVNEGHISTSLIQRHFQIGYNRAARIIDQLEQLGYVSSANGSKPRDVYVTEADLNKE
>NZ_CP025395.1|WP_001051855.1|1814654_1815077_-|YtxH-domain-containing-protein
MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQSYKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFEEEKSKFTEFDNKTDESIEKGKFDDEGGAAPNNNLRIVTEEDLKKNKNALSDKE
>NZ_CP025395.1|WP_001217116.1|1815093_1815789_-|rRNA-pseudouridine-synthase
MRIDKFLANMGVGTRNEVKQLLKKGLVNVNEQVIKSPKTHIEPENDKISVRGELIEYVENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLDKDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGVKLSDGKVKPAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYRLLTENDFDKLNYK
>NZ_CP025395.1|WP_000004344.1|1815785_1817447_-|polysaccharide-biosynthesis-protein
MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAPFTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGFLVLYFLAPYISELTLARNVHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYKSMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLWYYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHNGALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEMHHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAPVAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIALLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLGYLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR
>NZ_CP025395.1|WP_000284996.1|1817853_1819122_+|NAD(P)/FAD-dependent-oxidoreductase
MYQTIIIGGGPSGLMAAVAASEQSNNVLLIEKKKGLGRKLKISGGGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMFPVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVNTDQTFTVHTQSSSYVSHSLVIATGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVELSVLKKNGKKRISHQMDMLFTHFGISGPATLRCSQFVYKEQKNQKTQHISMAIDAFPELNHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLNDLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHGYTGGYNITSALVTGHVAGLYAGHYSHASME
>NZ_CP025395.1|WP_101305148.1|1819238_1825796_-|LPXTG-anchored-repetitive-surface-protein-SasC
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDTNVANNRGLANSAQNTPNQSATTNQSTNQALVNHNNGSIANQATPAPIQPSASPAQNNNHSDANSTATETVSNANNNDVVSNNTTLNVPNRTNENGSGGHLTLKEIQEDVRHSSDKPELVAIAEQASNRPKKRSRRAAPADPNATPADPAAAAAGNGGAPVAITAPYTPTTHPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPSVTVVDNLPGFTLINGGKVGVFSHAMVRTSMFDSGDAKNYQAQGNVIALGRIKGNDTNDHGDFNGIEKSLTVNPNSELIFEFNTMTTKNYQGVTNLIIKNADNDTVIAEKSVAYGPIWRLFKVPDNVSHLKIQFVPKNDAITDARGIYQLRDGYKYYDFVDSIGLHSGSHVYVERRTMEPTATNNKEFTVTTSLKNNGNFGASFNTDDFVYKVQLPEGVEYVNNSLTKDFPSSNSGVDMNDFNVTYDAANRVITIKSTGGGSGNSPARLMPDKILDLKYKLRVNNVPTPRTVTFNDTLTYKTYTQDFINSPAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNGLKRRAQTILDENRNNVPLNKRVSQADIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGDIGDQTTDAGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDATEDEIQDAINQLATDETDAIDNVTNATTNADVETAKNNGINTIGAVVPQVTHKKAARDAINQATATKRQQINSNREATQEEKDAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNANVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDARNAVNDKAREAITNINATPGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAFNQINQNQTNDQVDATTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALTKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMADITNNRTNQQVDDTTSQALDSIALVTPEHIVRAGARGAVKQQYEAKKQEIEQAEHATDEEKQVALNQLANNEKLALQNINQAVTNNDVKRVETNGIATLKGVQPHIVIKPEEQQAIKASAENQVESIKDTPHATVDELDEANQLISDTLKKAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNAAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSDRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKVIQSAPKVCTPIIKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>NZ_CP025395.1|WP_000836469.1|1826122_1826434_-|rhodanese-like-domain-containing-protein
MKSITTDELKNKLLESNPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLDVFNKNETYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>NZ_CP025395.1|WP_001803813.1|1826455_1828873_-|leucine--tRNA-ligase
MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNAEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>NZ_CP025395.1|WP_001025061.1|1829160_1830342_-|MFS-transporter
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPILYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>NZ_CP025395.1|WP_000526536.1|1830451_1831405_+|TIGR01212-family-radical-SAM-protein
MGNHFQYAFENKHYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>NZ_CP025395.1|WP_000764421.1|1831401_1831965_+|class-I-SAM-dependent-methyltransferase
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYMPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLYQKHAQVLQYQFLNQRNHAPFICAIEKIS

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Crispr_ID: NZ_CP025395_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025395_2

1923170-1923297

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025395_2

>merge|NZ_CP025395|2|1923170-1923297|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>NZ_CP025395|2|2|1923170-1923297|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025395.1\|WP_000886457.1\|1941514_1942351_-\|membrane-protein	unknown	unknown	gnl\|CDD\|224596
NZ_CP025395.1\|WP_000379980.1\|1917735_1918863_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	unknown	unknown	gnl\|CDD\|272993
NZ_CP025395.1\|WP_001251219.1\|1916502_1917102_-\|glucosamine-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|223440
NZ_CP025395.1\|WP_000597246.1\|1936215_1937952_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	unknown	unknown	gnl\|CDD\|224055
NZ_CP025395.1\|WP_000251253.1\|1938242_1938785_-\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NZ_CP025395.1\|WP_000869470.1\|1931857_1932808_-\|phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
NZ_CP025395.1\|WP_000901023.1\|1915269_1915665_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000379098.1\|1940276_1941254_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NZ_CP025395.1\|WP_000590809.1\|1919013_1919736_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP025395.1\|WP_000110011.1\|1931314_1931761_-\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NZ_CP025395.1\|WP_000181394.1\|1917260_1917731_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|223297
NZ_CP025395.1\|WP_000669377.1\|1912416_1913238_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP025395.1\|WP_000063549.1\|1921443_1922505_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP025395.1\|WP_001011598.1\|1933349_1934639_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493
NZ_CP025395.1\|WP_000116236.1\|1913688_1915074_-\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NZ_CP025395.1\|WP_000031108.1\|1916325_1916478_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000284739.1\|1939087_1940125_-\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_CP025395.1\|WP_001236371.1\|1934931_1936026_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP025395.1\|WP_000649894.1\|1919728_1921186_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP025395.1\|WP_000939525.1\|1932813_1933269_-\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|224146

Protein	Function_ID	Function_description	E-value
NZ_CP025395.1\|WP_000886457.1\|1941514_1942351_-\|membrane-protein	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	0.000182148
NZ_CP025395.1\|WP_000379980.1\|1917735_1918863_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	6.7316e-180
NZ_CP025395.1\|WP_001251219.1\|1916502_1917102_-\|glucosamine-6-phosphate-isomerase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
NZ_CP025395.1\|WP_000597246.1\|1936215_1937952_-\|SAV1866-family-putative-multidrug-efflux-ABC-transporter	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_CP025395.1\|WP_000251253.1\|1938242_1938785_-\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.12131e-126
NZ_CP025395.1\|WP_001011598.1\|1933349_1934639_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
NZ_CP025395.1\|WP_000590809.1\|1919013_1919736_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.70748e-153
NZ_CP025395.1\|WP_000110011.1\|1931314_1931761_-\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
NZ_CP025395.1\|WP_000181394.1\|1917260_1917731_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
NZ_CP025395.1\|WP_000669377.1\|1912416_1913238_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.45338e-78
NZ_CP025395.1\|WP_000063549.1\|1921443_1922505_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.46177e-121
NZ_CP025395.1\|WP_000116236.1\|1913688_1915074_-\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP025395.1\|WP_000869470.1\|1931857_1932808_-\|phosphoglycerate-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	8.44935e-135
NZ_CP025395.1\|WP_000284739.1\|1939087_1940125_-\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	2.81746e-156
NZ_CP025395.1\|WP_000379098.1\|1940276_1941254_+\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	2.87563e-40
NZ_CP025395.1\|WP_001236371.1\|1934931_1936026_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.5476e-86
NZ_CP025395.1\|WP_000649894.1\|1919728_1921186_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.12245e-98
NZ_CP025395.1\|WP_000939525.1\|1932813_1933269_-\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	6.6732e-69

>NZ_CP025395.1|WP_000063549.1|1921443_1922505_-|PTS-transporter-subunit-IIC
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFILKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>NZ_CP025395.1|WP_000649894.1|1919728_1921186_-|ABC-transporter-permease-subunit
MKCLIRFILILGLLISSAMVYINPTAHAEQDQTWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNNMLVKKDKVNEYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKVISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD
>NZ_CP025395.1|WP_000590809.1|1919013_1919736_-|amino-acid-ABC-transporter-ATP-binding-protein
MIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>NZ_CP025395.1|WP_000379980.1|1917735_1918863_-|tRNA-epoxyqueuosine(34)-reductase-QueG
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>NZ_CP025395.1|WP_000181394.1|1917260_1917731_-|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>NZ_CP025395.1|WP_001251219.1|1916502_1917102_-|glucosamine-6-phosphate-isomerase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>NZ_CP025395.1|WP_000031108.1|1916325_1916478_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>NZ_CP025395.1|WP_000901023.1|1915269_1915665_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>NZ_CP025395.1|WP_000116236.1|1913688_1915074_-|class-II-fumarate-hydratase
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHQSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>NZ_CP025395.1|WP_000669377.1|1912416_1913238_+|RluA-family-pseudouridine-synthase
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTIDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>NZ_CP025395.1|WP_000110011.1|1931314_1931761_-|peroxide-responsive-transcriptional-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>NZ_CP025395.1|WP_000869470.1|1931857_1932808_-|phosphoglycerate-dehydrogenase
MKVVGLNRMREVETELQQRFSGVDFKFYKKASEIPESDLANLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEVYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEPLLIEVLKSRVIRHAYLDVFENEPLKPNHELYKLDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNDLIENEVDAKKGY
>NZ_CP025395.1|WP_000939525.1|1932813_1933269_-|thioredoxin-dependent-thiol-peroxidase
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISSDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG
>NZ_CP025395.1|WP_001011598.1|1933349_1934639_+|glutamate-1-semialdehyde-2,1-aminomutase
MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
>NZ_CP025395.1|WP_001236371.1|1934931_1936026_+|aromatic-acid-exporter-family-protein
MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL
>NZ_CP025395.1|WP_000597246.1|1936215_1937952_-|SAV1866-family-putative-multidrug-efflux-ABC-transporter
MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDENYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGNIVETGTHRELIAKQGAYEHLYSIQNL
>NZ_CP025395.1|WP_000251253.1|1938242_1938785_-|DUF402-domain-containing-protein
MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKERYKKIRQY
>NZ_CP025395.1|WP_000284739.1|1939087_1940125_-|A/G-specific-adenine-glycosylase
MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVFDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVHDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTDAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFESEHARREMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGTINIETLPDDMIWFDLSDRDQYTFPVPMSKIYQFING
>NZ_CP025395.1|WP_000379098.1|1940276_1941254_+|metal-dependent-hydrolase
MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTNPFHVWMWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVIGLHPFAVFFPIIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDYVGKAYGRNVVFSDKVERQTLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTEIRLIDLRYLKNDHYSFVAIAHVTNDNVIDHSYIGWVFTEDKLQRKLYAK
>NZ_CP025395.1|WP_000886457.1|1941514_1942351_-|membrane-protein
MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIASETLFSFSHLTDVKEVRWLFRIIALIVFAVLMFTIYISYHHYMNDFLVTKLFNISAATPVVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLLTEKINIIFYGICVLCFLLLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISSMENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSNDSTDEADTSS

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Crispr_ID: NZ_CP025395_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025395_3

2001801-2001885

Orphan

Consensus_repeat	Method
TGTTGGGGTCCACACCCCAACTTGCA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_CP025395_3

>merge|NZ_CP025395|3|2001801-2001885|CRISPRCasFinder
TGTTGGGGTCCACACCCCAACTTGCATTGCCTGTAGAAATTGGTGTTCCAATTTCTCTATGTTGGGGCCCACACCCCAACTTGCA

>NZ_CP025395|3|3|2001801-2001885|CRISPRCasFinder
TGTTGGGGTCCACACCCCAACTTGCA	TTGCCTGTAGAAATTGGTGTTCCAATTTCTCTA
TGTTGGGGCCCACACCCCAACTTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025395.1\|WP_001250334.1\|2004697_2006011_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	unknown	unknown	gnl\|CDD\|223840
NZ_CP025395.1\|WP_025174666.1\|2003326_2003740_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000153530.1\|1997829_1998459_-\|two-component-system-response-regulator-VraR	unknown	unknown	gnl\|CDD\|225107
NZ_CP025395.1\|WP_001110179.1\|2000204_2000591_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000228666.1\|1995475_1995940_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP025395.1\|WP_000548781.1\|2009130_2009661_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_CP025395.1\|WP_001017131.1\|1998448_1999492_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP025395.1\|WP_001790679.1\|2006884_2006977_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000949467.1\|2006302_2006803_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_CP025395.1\|WP_000544977.1\|2003964_2004696_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_CP025395.1\|WP_000180460.1\|1995128_1995329_-\|DUF1128-family-protein	unknown	unknown	gnl\|CDD\|227177
NZ_CP025395.1\|WP_000428172.1\|1995946_1996222_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000613738.1\|2007193_2007748_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_CP025395.1\|WP_078071269.1\|1993869_1995126_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|376723
NZ_CP025395.1\|WP_001790257.1\|2003768_2003879_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000037081.1\|1996499_1997717_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_CP025395.1\|WP_000149070.1\|1999488_2000190_-\|cell-wall-active-antibiotics-response-protein	unknown	unknown	gnl\|CDD\|227100
NZ_CP025395.1\|WP_000140176.1\|2007814_2008885_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_CP025395.1\|WP_000999713.1\|2002151_2003138_+\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_CP025395.1\|WP_000636142.1\|2000807_2001566_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576

Protein	Function_ID	Function_description	E-value
NZ_CP025395.1\|WP_001250334.1\|2004697_2006011_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	9.47267e-98
NZ_CP025395.1\|WP_000153530.1\|1997829_1998459_-\|two-component-system-response-regulator-VraR	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
NZ_CP025395.1\|WP_000140176.1\|2007814_2008885_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_CP025395.1\|WP_000228666.1\|1995475_1995940_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
NZ_CP025395.1\|WP_001017131.1\|1998448_1999492_-\|sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
NZ_CP025395.1\|WP_000949467.1\|2006302_2006803_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NZ_CP025395.1\|WP_000544977.1\|2003964_2004696_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	2.59826e-119
NZ_CP025395.1\|WP_000180460.1\|1995128_1995329_-\|DUF1128-family-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
NZ_CP025395.1\|WP_000613738.1\|2007193_2007748_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
NZ_CP025395.1\|WP_078071269.1\|1993869_1995126_-\|aminopeptidase	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
NZ_CP025395.1\|WP_000037081.1\|1996499_1997717_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	2.99224e-85
NZ_CP025395.1\|WP_000149070.1\|1999488_2000190_-\|cell-wall-active-antibiotics-response-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	1.70542e-78
NZ_CP025395.1\|WP_000548781.1\|2009130_2009661_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
NZ_CP025395.1\|WP_000999713.1\|2002151_2003138_+\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	6.20478e-76
NZ_CP025395.1\|WP_000636142.1\|2000807_2001566_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126

>NZ_CP025395.1|WP_000636142.1|2000807_2001566_-|type-I-methionyl-aminopeptidase
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>NZ_CP025395.1|WP_001110179.1|2000204_2000591_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>NZ_CP025395.1|WP_000149070.1|1999488_2000190_-|cell-wall-active-antibiotics-response-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNRYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>NZ_CP025395.1|WP_001017131.1|1998448_1999492_-|sensor-histidine-kinase
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>NZ_CP025395.1|WP_000153530.1|1997829_1998459_-|two-component-system-response-regulator-VraR
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>NZ_CP025395.1|WP_000037081.1|1996499_1997717_+|YihY/virulence-factor-BrkB-family-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDTNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>NZ_CP025395.1|WP_000428172.1|1995946_1996222_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>NZ_CP025395.1|WP_000228666.1|1995475_1995940_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>NZ_CP025395.1|WP_000180460.1|1995128_1995329_-|DUF1128-family-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>NZ_CP025395.1|WP_078071269.1|1993869_1995126_-|aminopeptidase
MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGILEDGSKELVFENGNWASTF
>NZ_CP025395.1|WP_000999713.1|2002151_2003138_+|aromatic-acid-exporter-family-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>NZ_CP025395.1|WP_025174666.1|2003326_2003740_-|hypothetical-protein
MKPTKVILRDASYVHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEIKFEFALFDSDMDNLKHMEYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVTKSDFTKFINELASLH
>NZ_CP025395.1|WP_001790257.1|2003768_2003879_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_CP025395.1|WP_000544977.1|2003964_2004696_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGLVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>NZ_CP025395.1|WP_001250334.1|2004697_2006011_-|lipid-II-isoglutaminyl-synthase-subunit-MurT
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLVPMLEQLNRSFEGGQS
>NZ_CP025395.1|WP_000949467.1|2006302_2006803_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_CP025395.1|WP_001790679.1|2006884_2006977_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_CP025395.1|WP_000613738.1|2007193_2007748_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_CP025395.1|WP_000140176.1|2007814_2008885_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_CP025395.1|WP_000548781.1|2009130_2009661_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ

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Crispr_ID: NZ_CP025395_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025395_4

2194209-2194297

Orphan

Consensus_repeat	Method
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP025395_4

>merge|NZ_CP025395|4|2194209-2194297|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTATTTTACAACTTTAGTTGTTAGGGGCTCTTATGCA

>NZ_CP025395|4|4|2194209-2194297|CRISPRCasFinder
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA	TGCGCTTAGCGCAGGCGCTCCTATT
TTACAACTTTAGTTGTTAGGGGCTCTTATGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025395.1\|WP_000003759.1\|2191535_2191856_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP025395.1\|WP_000495686.1\|2193103_2194195_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000908617.1\|2198737_2200741_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226121
NZ_CP025395.1\|WP_000019740.1\|2191857_2192838_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP025395.1\|WP_000370933.1\|2194634_2195492_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP025395.1\|WP_001292149.1\|2207095_2207530_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP025395.1\|WP_000927350.1\|2204951_2207084_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP025395.1\|WP_001024102.1\|2190718_2191384_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP025395.1\|WP_001127960.1\|2189345_2190284_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_CP025395.1\|WP_001123307.1\|2186166_2186580_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP025395.1\|WP_000123406.1\|2187037_2188411_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP025395.1\|WP_000909236.1\|2195559_2196342_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP025395.1\|WP_000160304.1\|2184692_2185403_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP025395.1\|WP_001048277.1\|2208954_2216406_-\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
NZ_CP025395.1\|WP_000808817.1\|2189084_2189315_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000083812.1\|2203378_2204917_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP025395.1\|WP_000648723.1\|2207529_2208636_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP025395.1\|WP_000334466.1\|2200892_2202698_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP025395.1\|WP_000070865.1\|2185523_2185967_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP025395.1\|WP_000220900.1\|2194394_2194487_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP025395.1\|WP_000003759.1\|2191535_2191856_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP025395.1\|WP_000927350.1\|2204951_2207084_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.07884e-67
NZ_CP025395.1\|WP_000334466.1\|2200892_2202698_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP025395.1\|WP_000909236.1\|2195559_2196342_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	5.40486e-98
NZ_CP025395.1\|WP_001024102.1\|2190718_2191384_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.54377e-47
NZ_CP025395.1\|WP_001292149.1\|2207095_2207530_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP025395.1\|WP_000370933.1\|2194634_2195492_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	4.35599e-58
NZ_CP025395.1\|WP_001127960.1\|2189345_2190284_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NZ_CP025395.1\|WP_001123307.1\|2186166_2186580_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	4.41929e-45
NZ_CP025395.1\|WP_000123406.1\|2187037_2188411_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	6.10947e-06
NZ_CP025395.1\|WP_000908617.1\|2198737_2200741_-\|AAA-family-ATPase	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	2.02631e-29
NZ_CP025395.1\|WP_000160304.1\|2184692_2185403_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP025395.1\|WP_001048277.1\|2208954_2216406_-\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	7.3055e-109
NZ_CP025395.1\|WP_000083812.1\|2203378_2204917_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP025395.1\|WP_000019740.1\|2191857_2192838_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.73825e-109
NZ_CP025395.1\|WP_000070865.1\|2185523_2185967_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68
NZ_CP025395.1\|WP_000648723.1\|2207529_2208636_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0

>NZ_CP025395.1|WP_000495686.1|2193103_2194195_+|hypothetical-protein
MFTYFKSALKNAKPQLLITLIYAFIAFAVIAGVYLLANFQLAKYVQTIAIYSQFGQKPPGDAYLKAIAILLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGIYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDNKVVTEPKNTKVETDKVTTSVETKTEKAQDSLIDNTTKTMTSDKPEDNQPK
>NZ_CP025395.1|WP_000019740.1|2191857_2192838_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHQAHHHAHVH
>NZ_CP025395.1|WP_000003759.1|2191535_2191856_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP025395.1|WP_001024102.1|2190718_2191384_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQVISGEQDIKDALTQFENETD
>NZ_CP025395.1|WP_001127960.1|2189345_2190284_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP025395.1|WP_000808817.1|2189084_2189315_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP025395.1|WP_000123406.1|2187037_2188411_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKSPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP025395.1|WP_001123307.1|2186166_2186580_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLSVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP025395.1|WP_000070865.1|2185523_2185967_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP025395.1|WP_000160304.1|2184692_2185403_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_CP025395.1|WP_000220900.1|2194394_2194487_+|hypothetical-protein
MTYGSIIAIVCALFVIFFIPYMEKNNKKKK
>NZ_CP025395.1|WP_000370933.1|2194634_2195492_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLIEKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKHQQIYYEVFPFEGNRVSLKEDETWMRDMICSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLAKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTTYTNEEDGAAKYLAKHFLAD
>NZ_CP025395.1|WP_000909236.1|2195559_2196342_-|ABC-transporter-ATP-binding-protein
MLITLNHVGRLKQGKPILQDVSWQIDEGDKWVLYGLNGAGKTTLLNILNTYEPATSGTVNLFGKMPGKLGYSAENVRQQIGFVSHSLLEKFQEGETVIDVVMSGAFKSIGLYKNVDDDIISEAHQLLKLVEMSDKAQQFIGYLSTGEKQRVMIARALMGQPRILILDEPAAGLDFIARESLLNILDSLSDTYPTLAMIYVTHFIEEITANFSKILLLKDGQSIQQGAVEDILTSENMSYFFQKNVAVQKWNNRFSMAMLE
>NZ_CP025395.1|WP_000908617.1|2198737_2200741_-|AAA-family-ATPase
MLISELHISNFRSFGNESQMIEIADLTALIGANSSGKTSLIMALLRLFGQKNTDRTLIKTDFHIPESADISKINEIDLMIEEKVIFPELKLESPANIKTVPEFIKHLIIEETDADPYLRIRLKGKWIQGSTPEGNIEQELVYVKIPYGREEKEEDLTRVPIHHQKLIQMMYIPAMRDPAKQLKNASGTLLWRIFDGIDWPENLNDYIKSLTSPIETLFKEIPSIKDIQGILNNQWNKYHKDKRYSNSQFKFNGNSLQEFLKNAEILFNPTIDGNSVKVDSLGDGLKSLFYITLVSTLLEIENKQEKDDKPLLNILAIEEPENHISQHLLGRIVRNLKEISKKDNAQVILSSHNSSIIGKVDPEYIRHLQIQNSESIVNNITLPEKNDDAHTYIKEAVKAYPDLYFSKLVILGEGDSEEIVLPKLLSADNIYLDDFNISVVPLGGRYVNHMWKLLNDLSIPHVTLLDLDRERGGGDWGRIKYVLKQLDENNRCSEQLRTVLLIPSNTYHTYSMEEIEDFHNRKSNRLNSLNTWIEKLEKEDVFFSYPLDLDFTMLMSFQEEYQNTMERGPQIPKDSNSTEYDEKLKKSIQATLKNEKAIAKTYSEDEKKLMIWYNSLFLGRGKPSTHIAALKDIDENEIIENAPKELLRLIQRVKEKVGLVGGSNIDE
>NZ_CP025395.1|WP_000334466.1|2200892_2202698_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVTLQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP025395.1|WP_000083812.1|2203378_2204917_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIVGFKVLAPIMKFIMYILSVAVESLVHAHLLPVVSILVEPAKILFLNNAINHGVFTPLGTDQAAKVGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKTPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP025395.1|WP_000927350.1|2204951_2207084_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGEDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAEQLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNEFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP025395.1|WP_001292149.1|2207095_2207530_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP025395.1|WP_000648723.1|2207529_2208636_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP025395.1|WP_001048277.1|2208954_2216406_-|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPTAQPAAPANQGQPAAQPAAQPANQGGQANPAGGAAQPNTQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPANQTQPANAPAVAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQNANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADNILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDAKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTAQGVTTEKDNGIAVLDQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTAPATTAKAAALEEFDEVDQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEISKIENITDSTQTKMDAYNEVKQAATARKAQNATVSNTTNEEVAEADAAVEAAQKQGLHDIQVVKSKQEVAETKSKVLDKINAIQTHAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKQAAYTELDTKKQEARTNLDAANSNSEVATAKDNGITAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANTDIDNAAANTDVDNAKTTNEATIAAITPDANVKPTAKQAIADKVQAQETAIDANNGETTEEKATAKQQVQTEKTTADTAIDGAHSNAEVEAAKNAEIAKIEAIQPATTTKDDAKQAITTKANERKTAIAQTQDITAEEIAAANANVDNAVTQANSNIEAANSQNDVEQAKTTGETSIDQVTPTVNKKATARNEITTILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQVAPTSVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADVQGITADTTIKDVAKDELATKAKEQKALIAQTADATTEEKEQANQQVDAELTQGNQNIENAQSIDDVNTAKDNAIQAIDPILASTDVKTNARAELLTEMQNKITEILSDNTTTNEEKGKDIEPVRATYEEGLNNINTANTTGDVTTAKDTAVQKVQQLHANPVKKPAGKTALDQAAADRKTQIEQTPNASQQEINDAKQEVDAALNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIADAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKETATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALESINNGVDNGDVDDALTQGKAAIDAIQVDATVKPKANQVIDAKAEETKESIDQSDQLTAEEKTEALAMIKQITDQAKKGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPNANDTNSGSDNNDATANSNANATPENTGQPNVTESTDNANADTSSTTTNNQNDAATGGTTATSTNNPSTDDANDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPATETDNATPAESTINNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNAAVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPKVSSNTEKDKKESTTNQTDAEQHNSDTNVTSNEVVKSPSKADTDVSNKPSTSKPSEAKDKMTSTNVSQTDDTATADTNDTQKSVGSAANNKVKDMQTNDMKAPLATVSKGSNSANQDMLKVTNTDKHQAKATSAQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: NZ_CP025395_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP025395_5

2317933-2318019

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP025395_5

>merge|NZ_CP025395|5|2317933-2318019|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGTCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGTCTTTC

>NZ_CP025395|5|5|2317933-2318019|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTC	CGTCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGTCTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP025395.1\|WP_000951058.1\|2315407_2315848_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP025395.1\|WP_000076916.1\|2323378_2324383_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NZ_CP025395.1\|WP_031901223.1\|2317628_2317799_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_001566779.1\|2314237_2314489_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000808500.1\|2320081_2320528_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP025395.1\|WP_000134535.1\|2322345_2322840_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP025395.1\|WP_000051210.1\|2308396_2308561_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000413855.1\|2312583_2313849_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP025395.1\|WP_000230173.1\|2318194_2319217_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP025395.1\|WP_000913009.1\|2324551_2325157_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NZ_CP025395.1\|WP_000592316.1\|2309299_2312467_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP025395.1\|WP_001161080.1\|2308795_2309113_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP025395.1\|WP_000066900.1\|2317152_2317503_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP025395.1\|WP_000259726.1\|2321023_2322283_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP025395.1\|WP_000184420.1\|2315840_2317052_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP025395.1\|WP_000602951.1\|2320541_2321027_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP025395.1\|WP_000600960.1\|2314480_2315245_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP025395.1\|WP_000503816.1\|2322841_2323348_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP025395.1\|WP_000643988.1\|2319236_2319836_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP025395.1\|WP_000866967.1\|2319842_2320076_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452

Protein	Function_ID	Function_description	E-value
NZ_CP025395.1\|WP_000951058.1\|2315407_2315848_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_CP025395.1\|WP_000076916.1\|2323378_2324383_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	1.44045e-130
NZ_CP025395.1\|WP_000808500.1\|2320081_2320528_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NZ_CP025395.1\|WP_000413855.1\|2312583_2313849_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	8.95714e-143
NZ_CP025395.1\|WP_000230173.1\|2318194_2319217_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP025395.1\|WP_000913009.1\|2324551_2325157_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	4.38506e-114
NZ_CP025395.1\|WP_000592316.1\|2309299_2312467_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP025395.1\|WP_000866967.1\|2319842_2320076_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	5.99629e-25
NZ_CP025395.1\|WP_000066900.1\|2317152_2317503_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP025395.1\|WP_000134535.1\|2322345_2322840_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	4.27584e-97
NZ_CP025395.1\|WP_000184420.1\|2315840_2317052_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.72084e-71
NZ_CP025395.1\|WP_000602951.1\|2320541_2321027_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	1.7369e-49
NZ_CP025395.1\|WP_000600960.1\|2314480_2315245_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	6.28857e-38
NZ_CP025395.1\|WP_000503816.1\|2322841_2323348_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	3.92413e-65
NZ_CP025395.1\|WP_000643988.1\|2319236_2319836_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NZ_CP025395.1\|WP_000259726.1\|2321023_2322283_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.192e-158

>NZ_CP025395.1|WP_031901223.1|2317628_2317799_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDMGCDINVKEPLKIYYVVILKSGIEMIFS
>NZ_CP025395.1|WP_000066900.1|2317152_2317503_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP025395.1|WP_000184420.1|2315840_2317052_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLNAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP025395.1|WP_000951058.1|2315407_2315848_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP025395.1|WP_000600960.1|2314480_2315245_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQIEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWYDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP025395.1|WP_001566779.1|2314237_2314489_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>NZ_CP025395.1|WP_000413855.1|2312583_2313849_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP025395.1|WP_000592316.1|2309299_2312467_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEVDKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSIVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP025395.1|WP_001161080.1|2308795_2309113_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVIFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP025395.1|WP_000051210.1|2308396_2308561_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NZ_CP025395.1|WP_000230173.1|2318194_2319217_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP025395.1|WP_000643988.1|2319236_2319836_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP025395.1|WP_000866967.1|2319842_2320076_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIMLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP025395.1|WP_000808500.1|2320081_2320528_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP025395.1|WP_000602951.1|2320541_2321027_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRYIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP025395.1|WP_000259726.1|2321023_2322283_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP025395.1|WP_000134535.1|2322345_2322840_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKSMIIGETYLESKSGGKSGDFQRQSGQ
>NZ_CP025395.1|WP_000503816.1|2322841_2323348_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITMQVKKWLKEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP025395.1|WP_000076916.1|2323378_2324383_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFIEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSACTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP025395.1|WP_000913009.1|2324551_2325157_-|ATP-binding-cassette-domain-containing-protein
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAQNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP025395_3	3.1\|2001827\|33\|NZ_CP025395\|CRISPRCasFinder	2001827-2001859	33	NZ_CP025395.1	1843293-1843325	0	1.0
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	1164351-1164375	0	1.0
NZ_CP025395_3	3.1\|2001827\|33\|NZ_CP025395\|CRISPRCasFinder	2001827-2001859	33	NZ_CP025395.1	2001712-2001744	1	0.97
NZ_CP025395_3	3.1\|2001827\|33\|NZ_CP025395\|CRISPRCasFinder	2001827-2001859	33	NZ_CP025395.1	2073127-2073159	1	0.97
NZ_CP025395_3	3.1\|2001827\|33\|NZ_CP025395\|CRISPRCasFinder	2001827-2001859	33	NZ_CP025395.1	2750521-2750553	1	0.97
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	205069-205093	1	0.96
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	634965-634989	1	0.96
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	1446861-1446885	1	0.96
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	1669753-1669777	1	0.96
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	2090449-2090473	1	0.96
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	2454330-2454354	1	0.96
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	2508540-2508564	1	0.96
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	833116-833140	2	0.92
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	1160320-1160344	2	0.92
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	1757133-1757157	2	0.92
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	2001907-2001931	2	0.92
NZ_CP025395_5	5.1\|2317964\|25\|NZ_CP025395\|CRISPRCasFinder	2317964-2317988	25	NZ_CP025395.1	2454386-2454410	2	0.92

1. spacer 3.1|2001827|33|NZ_CP025395|CRISPRCasFinder matches to position: 1843293-1843325, mismatch: 0, identity: 1.0

ttgcctgtagaaattggtgttccaatttctcta	CRISPR spacer
ttgcctgtagaaattggtgttccaatttctcta	Protospacer
*********************************

2. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 1164351-1164375, mismatch: 0, identity: 1.0

cgtcagcttctatgttggggccccg	CRISPR spacer
cgtcagcttctatgttggggccccg	Protospacer
*************************

3. spacer 3.1|2001827|33|NZ_CP025395|CRISPRCasFinder matches to position: 2001712-2001744, mismatch: 1, identity: 0.97

ttgcctgtagaaattggtgttccaatttctcta	CRISPR spacer
ttgtctgtagaaattggtgttccaatttctcta	Protospacer
***.*****************************

4. spacer 3.1|2001827|33|NZ_CP025395|CRISPRCasFinder matches to position: 2073127-2073159, mismatch: 1, identity: 0.97

ttgcctgtagaaattggtgttccaatttctcta	CRISPR spacer
ttgtctgtagaaattggtgttccaatttctcta	Protospacer
***.*****************************

5. spacer 3.1|2001827|33|NZ_CP025395|CRISPRCasFinder matches to position: 2750521-2750553, mismatch: 1, identity: 0.97

ttgcctgtagaaattggtgttccaatttctcta	CRISPR spacer
ttgcctgttgaaattggtgttccaatttctcta	Protospacer
******** ************************

6. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 205069-205093, mismatch: 1, identity: 0.96

cgtcagcttctatgttggggccccg	CRISPR spacer
cgccagcttctatgttggggccccg	Protospacer
**.**********************

7. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 634965-634989, mismatch: 1, identity: 0.96

cgtcagcttctatgttggggccccg	CRISPR spacer
cgccagcttctatgttggggccccg	Protospacer
**.**********************

8. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 1446861-1446885, mismatch: 1, identity: 0.96

cgtcagcttctatgttggggccccg	CRISPR spacer
cgccagcttctatgttggggccccg	Protospacer
**.**********************

9. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 1669753-1669777, mismatch: 1, identity: 0.96

cgtcagcttctatgttggggccccg	CRISPR spacer
cgtcagcttctatgttgaggccccg	Protospacer
*****************.*******

10. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 2090449-2090473, mismatch: 1, identity: 0.96

cgtcagcttctatgttggggccccg	CRISPR spacer
cgccagcttctatgttggggccccg	Protospacer
**.**********************

11. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 2454330-2454354, mismatch: 1, identity: 0.96

cgtcagcttctatgttggggccccg	CRISPR spacer
cgtcagcttctgtgttggggccccg	Protospacer
***********.*************

12. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 2508540-2508564, mismatch: 1, identity: 0.96

cgtcagcttctatgttggggccccg	CRISPR spacer
cgccagcttctatgttggggccccg	Protospacer
**.**********************

13. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 833116-833140, mismatch: 2, identity: 0.92

cgtcagcttctatgttggggccccg	CRISPR spacer
cgtcagcttttatgttgtggccccg	Protospacer
*********.******* *******

14. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 1160320-1160344, mismatch: 2, identity: 0.92

cgtcagcttctatgttggggccccg	CRISPR spacer
cgccagcttctgtgttggggccccg	Protospacer
**.********.*************

15. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 1757133-1757157, mismatch: 2, identity: 0.92

cgtcagcttctatgttggggccccg	CRISPR spacer
cgtcaccttctgtgttggggccccg	Protospacer
***** *****.*************

16. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 2001907-2001931, mismatch: 2, identity: 0.92

cgtcagcttctatgttggggccccg	CRISPR spacer
cgtcagcttctgtgttggcgccccg	Protospacer
***********.****** ******

17. spacer 5.1|2317964|25|NZ_CP025395|CRISPRCasFinder matches to position: 2454386-2454410, mismatch: 2, identity: 0.92

cgtcagcttctatgttggggccccg	CRISPR spacer
cgccagcttctgtgttggggccccg	Protospacer
**.********.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

328526 : 372461

Staphylococcus_phage(78.18%)

head,tail,portal,terminase,capsid,plate,protease,integrase,holin

attL 328415:328433|attR 374630:374648

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
328415:328433	attL	NA	NA	NA	NA
WP_000264757.1\|328526_329732_-\|integrase	site-specific integrase	A0A1X9H094	Staphylococcus_phage	7.5e-218	97.8
WP_001108428.1\|329834_330485_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000755716.1\|330957_331392_-	hypothetical protein	A0A2K9VBS2	Staphylococcus_phage	1.2e-24	98.6
WP_000524999.1\|331409_331871_-	hypothetical protein	A0A2I6PEK4	Staphylococcus_phage	3.7e-85	98.7
WP_000429766.1\|331883_332213_-	helix-turn-helix transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
WP_001115060.1\|332373_332565_+	helix-turn-helix transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
WP_001001356.1\|332652_332829_+	hypothetical protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
WP_000549547.1\|332825_333056_-	hypothetical protein	A0A0H3U2T9	Staphylococcus_phage	6.1e-36	98.7
WP_001148592.1\|333112_333865_+	phage antirepressor KilAC domain-containing protein	S4SW96	Staphylococcus_phage	2.4e-137	98.8
WP_001202628.1\|333880_334078_+	hypothetical protein	A7TWF5	Staphylococcus_phage	1.9e-22	93.8
WP_001124184.1\|334222_334486_+	helix-turn-helix domain-containing protein	B7T0G2	Staphylococcus_virus	1.1e-44	98.9
WP_001205781.1\|334498_334660_+	DUF1270 domain-containing protein	A9CR58	Staphylococcus_phage	3.3e-20	96.2
WP_000174996.1\|334737_335061_+	hypothetical protein	B7T0G4	Staphylococcus_virus	8.5e-52	100.0
WP_000985978.1\|335075_335438_+	hypothetical protein	A7TWG3	Staphylococcus_phage	3.0e-53	95.8
WP_000801407.1\|335434_336601_+	DUF2800 domain-containing protein	B7T0G6	Staphylococcus_virus	9.4e-218	97.9
WP_000645046.1\|336626_337184_+	DUF2815 family protein	A0A2K9VBT2	Staphylococcus_phage	2.0e-96	99.5
WP_001164628.1\|339217_339403_+	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	2.1e-26	98.4
WP_000113974.1\|339402_339804_+	PVL family protein	A0A2I6PEL5	Staphylococcus_phage	1.2e-68	100.0
WP_000022737.1\|339803_340058_+	DUF3310 domain-containing protein	A0A059T7J9	Staphylococcus_phage	6.3e-42	98.8
WP_078071252.1\|340057_340306_+	hypothetical protein	E9LT32	Staphylococcus_phage	4.8e-39	95.0
WP_000695750.1\|340320_340731_+	hypothetical protein	A0A1P8CN10	Staphylococcus_phage	2.1e-47	69.1
WP_101305136.1\|340730_341006_+	hypothetical protein	Q4ZA41	Staphylococcus_virus	6.6e-45	98.9
WP_001065080.1\|340998_341247_+	DUF1024 family protein	C8CH04	Staphylococcus_phage	1.6e-37	98.8
WP_000185699.1\|341239_341776_+	dUTP diphosphatase	A0A1P8L6E0	Staphylococcus_phage	1.4e-94	99.4
WP_001804400.1\|341836_342097_+	hypothetical protein	NA	NA	NA	NA
WP_000195824.1\|342316_342523_+	DUF1381 domain-containing protein	Q4ZCV6	Staphylococcus_virus	7.1e-20	98.5
WP_000595213.1\|342519_342672_+	transcriptional activator RinB	B7T0I1	Staphylococcus_virus	1.2e-19	98.0
WP_000265259.1\|342739_342940_+	DUF1514 family protein	A0A2I6PEG6	Staphylococcus_phage	5.5e-25	97.0
WP_000884862.1\|342988_345436_+	virulence-associated E family protein	B7T0I3	Staphylococcus_virus	0.0e+00	98.4
WP_078061081.1\|345544_345643_-	hypothetical protein	Q4ZCF8	Staphylococcus_virus	2.2e-11	96.9
WP_000665203.1\|345776_346067_+	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
WP_000528512.1\|347427_347865_+	transcriptional regulator	A0A2I6PEN3	Staphylococcus_phage	7.9e-77	100.0
WP_000160690.1\|348021_348336_+	HNH endonuclease	A0A2I6PDC4	Staphylococcus_phage	1.6e-55	98.1
WP_000778933.1\|348463_348769_+\|terminase	P27 family phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
WP_000153542.1\|348758_350450_+\|terminase	terminase large subunit	Q9B0E3	Staphylococcus_virus	0.0e+00	99.1
WP_001100666.1\|350454_351693_+\|portal	phage portal protein	A0A2I6PER5	Staphylococcus_phage	1.0e-233	99.3
WP_000061876.1\|351676_352450_+\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	4.6e-136	98.8
WP_001142731.1\|352461_353625_+\|capsid	phage major capsid protein	A0A2I6PDD7	Staphylococcus_phage	1.5e-215	99.0
WP_000050976.1\|353693_353972_+\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	6.0e-46	98.9
WP_000395496.1\|353983_354316_+	hypothetical protein	M9QX19	Staphylococcus_phage	2.4e-57	99.1
WP_000110017.1\|354312_354714_+	hypothetical protein	A0A0K1LL98	Staphylococcus_phage	1.1e-67	100.0
WP_001023807.1\|354714_355110_+	DUF3168 domain-containing protein	A0A0K1LKC0	Staphylococcus_phage	1.5e-66	99.2
WP_000807538.1\|355144_355786_+\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	1.8e-117	98.1
WP_000169134.1\|355877_356333_+	Ig domain-containing protein	Q9B0D4	Staphylococcus_phage	1.2e-75	98.0
WP_000589167.1\|356390_356741_+	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000438833.1\|356782_356941_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_001003409.1\|356954_363155_+\|tail	phage tail tape measure protein	A0A0K1LKC4	Staphylococcus_phage	0.0e+00	98.8
WP_001190535.1\|363154_363979_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	1.6e-158	99.6
WP_000384458.1\|363987_365571_+\|tail	phage tail protein	Q4ZD01	Staphylococcus_virus	3.6e-305	99.1
WP_000179860.1\|365570_365861_+	hypothetical protein	A0A2I6PF46	Staphylococcus_phage	2.1e-49	100.0
WP_000429563.1\|365876_367787_+	hypothetical protein	A0A2I6PF35	Staphylococcus_phage	0.0e+00	99.4
WP_000067157.1\|367786_369253_+\|plate	phage baseplate upper protein	A0A2I6PDQ5	Staphylococcus_phage	1.8e-250	97.5
WP_001166604.1\|369252_369642_+	DUF2977 domain-containing protein	Q4ZCZ7	Staphylococcus_virus	6.4e-62	96.9
WP_000916020.1\|369634_369799_+	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_000466773.1\|369844_370144_+	DUF2951 family protein	M9QRV2	Staphylococcus_phage	2.2e-30	98.0
WP_070003492.1\|370531_370642_-	hypothetical protein	NA	NA	NA	NA
WP_000448764.1\|370692_370995_+\|holin	phage holin	B7T0L0	Staphylococcus_virus	3.8e-46	94.0
WP_000930277.1\|371006_372461_+	N-acetylmuramoyl-L-alanine amidase	A0A0N6WMR3	Staphylococcus_phage	1.7e-280	96.1
374630:374648	attR	NA	NA	NA	NA

DBSCAN-SWA_2

417446 : 459094

Staphylococcus_phage(80.0%)

transposase,terminase,capsid,coat,protease,integrase

attL 414527:414542|attR 438568:438583

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
414527:414542	attL	NA	NA	NA	NA
WP_001052483.1\|417446_417638_-	hypothetical protein	U3PCX8	Staphylococcus_phage	4.9e-23	80.0
WP_001261460.1\|417881_418178_+	30S ribosomal protein S6	NA	NA	NA	NA
WP_000934799.1\|418198_418702_+	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	1.2e-60	74.7
WP_000897044.1\|418753_418996_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_000270123.1\|419236_420466_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	2.9e-217	96.2
WP_000668212.1\|420922_421618_-	helix-turn-helix transcriptional regulator	Q4ZE79	Staphylococcus_phage	2.3e-09	62.5
WP_000794656.1\|421761_421974_+	helix-turn-helix transcriptional regulator	Q4ZE78	Staphylococcus_phage	2.6e-17	61.4
WP_000091734.1\|421974_422247_+	winged helix-turn-helix domain-containing protein	Q4ZE77	Staphylococcus_phage	3.9e-42	92.2
WP_031824147.1\|422258_422405_+	hypothetical protein	NA	NA	NA	NA
WP_001058493.1\|422397_422607_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	5.3e-31	98.6
WP_001103963.1\|422609_422936_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	2.3e-49	89.8
WP_001002726.1\|423000_423870_+	primase C-terminal domain-containing protein	Q4ZE74	Staphylococcus_phage	1.4e-162	94.5
WP_000447457.1\|423883_425593_+	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	0.0e+00	99.5
WP_000356937.1\|425904_426285_+	hypothetical protein	Q4ZE71	Staphylococcus_phage	6.9e-69	100.0
WP_001019787.1\|426281_426923_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	4.2e-111	93.4
WP_001190600.1\|427269_427611_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	8.4e-58	99.1
WP_000846276.1\|427622_428201_+	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	3.7e-29	38.4
WP_000853271.1\|428218_428437_+\|capsid	capsid morphogenesis B protein	NA	NA	NA	NA
WP_000765272.1\|428487_429015_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	6.8e-83	92.0
WP_078064908.1\|429146_429359_+	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	1.2e-30	95.7
WP_001293094.1\|429355_429925_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	2.5e-99	96.3
WP_000768417.1\|430031_430382_+	complement inhibitor SCIN family protein	A7TWS0	Staphylococcus_phage	2.1e-19	50.4
WP_000731022.1\|430640_432140_+	von Willebrand factor binding protein Vwb	NA	NA	NA	NA
WP_001804276.1\|432550_432733_+	hypothetical protein	Q4ZE84	Staphylococcus_phage	4.6e-23	98.3
WP_000813314.1\|432851_433364_+	hypothetical protein	Q4ZE83	Staphylococcus_phage	5.5e-69	99.4
WP_000166620.1\|434026_434752_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001080631.1\|435391_436399_-	Abi family protein	NA	NA	NA	NA
WP_000475322.1\|437316_437928_+	hypothetical protein	NA	NA	NA	NA
WP_000849165.1\|438296_438665_+	YxeA family protein	NA	NA	NA	NA
438568:438583	attR	NA	NA	NA	NA
WP_001055897.1\|439555_439819_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000466742.1\|440112_440367_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_031901230.1\|440405_440615_-	hypothetical protein	NA	NA	NA	NA
WP_000158372.1\|440792_441374_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_000746682.1\|442091_442718_-	NDxxF motif lipoprotein	NA	NA	NA	NA
WP_000930494.1\|443162_444686_-	alkyl hydroperoxide reductase subunit F	A0A249XZT7	Enterococcus_phage	4.2e-40	33.2
WP_000052781.1\|444701_445271_-	peroxiredoxin	NA	NA	NA	NA
WP_001279728.1\|445762_446518_+	oxygen-insensitive NADPH nitroreductase	NA	NA	NA	NA
WP_000990998.1\|446597_447986_-	L-cystine transporter	NA	NA	NA	NA
WP_031901229.1\|448070_448172_+	hypothetical protein	NA	NA	NA	NA
WP_000956148.1\|448961_449918_-	hypothetical protein	NA	NA	NA	NA
WP_000394705.1\|450035_450698_-	hypothetical protein	NA	NA	NA	NA
WP_000763770.1\|450840_451248_-	general stress protein	NA	NA	NA	NA
WP_000421405.1\|451760_452339_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_000793022.1\|452338_453607_+	purine permease	NA	NA	NA	NA
WP_000264071.1\|453644_455111_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5
WP_000424963.1\|455135_456677_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
WP_000551645.1\|456789_457326_-	hypothetical protein	NA	NA	NA	NA
WP_000041877.1\|457717_458422_-	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	3.4e-29	37.6
WP_000159790.1\|458821_459094_-\|transposase	IS3 family transposase	A0A0C5AJ30	Paenibacillus_phage	2.0e-14	52.9

DBSCAN-SWA_3

770172 : 777992

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|770172_771228_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|771227_771914_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|771888_772362_-	DoxX family protein	NA	NA	NA	NA
WP_001093558.1\|772703_773144_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637683.1\|773423_774008_-	hypothetical protein	NA	NA	NA	NA
WP_001062966.1\|774106_774820_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	5.0e-52	43.5
WP_000941336.1\|774823_775243_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|775244_775913_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604519.1\|776263_776857_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	5.8e-38	42.9
WP_001217797.1\|776840_777992_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_4

789964 : 804509

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663031.1\|789964_791023_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	2.3e-21	26.4
WP_000197268.1\|791317_791866_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429017.1\|792467_793385_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.4
WP_000193751.1\|793665_795171_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930015.1\|795517_796012_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.8e-52	71.5
WP_001068497.1\|796031_796898_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|797697_798096_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855518.1\|798058_800164_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|800281_801253_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_031901244.1\|801642_801798_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|801836_802808_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245571.1\|802794_803751_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	7.2e-06	60.0
WP_000616869.1\|803747_804509_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	5.0e-18	31.6

DBSCAN-SWA_5

1049299 : 1057772

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025174670.1\|1049299_1049782_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.2e-20	44.0
WP_001010393.1\|1049768_1050893_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174052.1\|1050896_1051601_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	2.8e-47	42.1
WP_000848350.1\|1051600_1051864_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1051865_1052537_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_043039658.1\|1052529_1054719_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-140	39.7
WP_000483719.1\|1054697_1056182_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.5e-45	31.5
WP_000030807.1\|1056174_1057203_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	6.5e-61	41.4
WP_000238667.1\|1057205_1057772_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.0e-29	39.6

DBSCAN-SWA_6

1607041 : 1615353

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1607041_1607827_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924215.1\|1607952_1608843_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062177.1\|1608852_1610199_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683919.1\|1610312_1611413_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	1.0e-08	30.6
WP_000624562.1\|1611415_1612093_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1612223_1613330_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217249.1\|1613553_1615353_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_7

1684948 : 1693991

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364543.1\|1684948_1685467_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.1e-28	45.8
WP_000594980.1\|1685488_1687762_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	4.7e-64	29.5
WP_000749803.1\|1687964_1690244_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1690518_1690779_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1690797_1691937_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019179.1\|1691959_1692985_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1692986_1693991_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1819238 : 1886383

Staphylococcus_phage(90.24%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101305148.1\|1819238_1825796_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.8e-302	95.7
WP_000836469.1\|1826122_1826434_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
WP_001803813.1\|1826455_1828873_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_001025061.1\|1829160_1830342_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526536.1\|1830451_1831405_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764421.1\|1831401_1831965_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	2.7e-101	98.4
WP_000757540.1\|1832084_1832486_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1833059_1833887_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|1833889_1834009_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1834120_1835122_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|1835243_1835708_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159026.1\|1835720_1836902_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.9e-226	99.2
WP_000493882.1\|1836912_1837545_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-111	98.6
WP_000077346.1\|1837551_1838595_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	3.1e-196	99.1
WP_001261655.1\|1839075_1840578_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.1e-29	98.6
WP_000221182.1\|1841099_1841414_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	3.7e-52	96.2
WP_000989111.1\|1841413_1842706_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.0e-225	98.1
WP_000163240.1\|1842723_1843119_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	2.4e-72	99.2
WP_001032833.1\|1843467_1844322_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1844597_1844822_-	hypothetical protein	NA	NA	NA	NA
WP_001153740.1\|1845599_1846043_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1846029_1846473_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168908.1\|1846770_1847406_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1847831_1848545_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1848802_1849105_+	hypothetical protein	NA	NA	NA	NA
WP_001200548.1\|1849360_1849726_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.1e-58	97.5
WP_000623471.1\|1849722_1850076_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453299.1\|1850325_1851159_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.7e-157	98.9
WP_000366159.1\|1851370_1852279_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	4.4e-138	99.7
WP_050963930.1\|1852422_1853739_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	9.2e-44	33.0
WP_000933822.1\|1853908_1855102_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109901.1\|1855473_1857066_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.6
WP_001803969.1\|1857362_1858109_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.6e-141	98.0
WP_000669096.1\|1858113_1858587_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	6.1e-83	97.5
WP_000718107.1\|1858652_1858910_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778531.1\|1858906_1859908_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	1.9e-182	96.7
WP_000348361.1\|1859912_1861391_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	5.8e-281	97.2
WP_001803971.1\|1861549_1862005_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	2.8e-77	96.6
WP_001803972.1\|1862307_1862958_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.5e-50	78.7
WP_000070662.1\|1863038_1864034_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	4.3e-70	95.6
WP_000669042.1\|1864109_1864736_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.3e-76	80.8
WP_000627545.1\|1864776_1865121_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	3.0e-55	95.6
WP_000414228.1\|1865218_1865791_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.2e-24	93.1
WP_000190484.1\|1866166_1867003_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000809858.1\|1867808_1867994_-	hypothetical protein	NA	NA	NA	NA
WP_000375476.1\|1867995_1868172_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1868182_1868566_-	hypothetical protein	NA	NA	NA	NA
WP_000747809.1\|1869252_1869699_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_001801861.1\|1870150_1870246_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791232.1\|1870368_1870470_+	hypothetical protein	NA	NA	NA	NA
WP_000072598.1\|1876006_1877206_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	3.7e-225	97.7
WP_001038722.1\|1879116_1879836_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	7.3e-128	97.5
WP_101305149.1\|1880738_1881461_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	9.0e-126	95.0
WP_001039436.1\|1881585_1882293_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	8.2e-124	96.2
WP_101305150.1\|1884865_1886383_-\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	2.2e-49	50.9

DBSCAN-SWA_9

1917260 : 1991800

Staphylococcus_phage(76.27%)

transposase,head,tail,portal,capsid,tRNA,terminase,protease,integrase,holin

attL 1959808:1959822|attR 1993357:1993371

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181394.1\|1917260_1917731_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_000379980.1\|1917735_1918863_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_000590809.1\|1919013_1919736_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	42.7
WP_000649894.1\|1919728_1921186_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_000063549.1\|1921443_1922505_-	PTS transporter subunit IIC	NA	NA	NA	NA
WP_000110011.1\|1931314_1931761_-	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
WP_000869470.1\|1931857_1932808_-	phosphoglycerate dehydrogenase	NA	NA	NA	NA
WP_000939525.1\|1932813_1933269_-	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_001011598.1\|1933349_1934639_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_001236371.1\|1934931_1936026_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_000597246.1\|1936215_1937952_-	SAV1866 family putative multidrug efflux ABC transporter	W8CYL7	Bacillus_phage	2.2e-53	30.4
WP_000251253.1\|1938242_1938785_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_000284739.1\|1939087_1940125_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000379098.1\|1940276_1941254_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_000886457.1\|1941514_1942351_-	membrane protein	NA	NA	NA	NA
WP_000535832.1\|1942359_1943877_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000435806.1\|1943891_1944206_-	YfhH family protein	NA	NA	NA	NA
WP_001124431.1\|1944183_1945002_-	recombination regulator RecX	NA	NA	NA	NA
WP_000830380.1\|1945262_1946072_-	monofunctional peptidoglycan glycosyltransferase SgtB	NA	NA	NA	NA
WP_078071271.1\|1946329_1947847_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	2.2e-49	50.9
WP_000163283.1\|1948015_1948531_-	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_001005407.1\|1948660_1948822_-	hypothetical protein	NA	NA	NA	NA
WP_101305152.1\|1949148_1949250_+	hypothetical protein	NA	NA	NA	NA
WP_000593870.1\|1949294_1950296_-	restriction endonuclease subunit S	A0A1W6JNN3	Staphylococcus_phage	1.0e-55	40.1
WP_001003361.1\|1950279_1952172_-	N-6 DNA methylase	A0A1W6JNK1	Staphylococcus_phage	5.6e-268	70.9
WP_000669581.1\|1952683_1953652_-	bi-component leukocidin LukMF' subunit F'	Q9MBN2	Staphylococcus_prophage	7.7e-181	99.7
WP_000476436.1\|1953653_1954580_-	bi-component leukocidin LukMF' subunit M	Q9MBN3	Staphylococcus_prophage	4.2e-176	99.7
WP_000861033.1\|1954928_1955684_-	CHAP domain-containing protein	Q9MBN4	Staphylococcus_prophage	3.4e-152	100.0
WP_000611513.1\|1955695_1955950_-\|holin	phage holin	Q9MBN5	Staphylococcus_prophage	5.3e-41	100.0
WP_000539688.1\|1956488_1956785_-	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_001040261.1\|1956842_1957130_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_001153680.1\|1957176_1957329_-	hypothetical protein	D2JLG0	Staphylococcus_phage	1.2e-19	98.0
WP_000582145.1\|1957318_1961104_-	hypothetical protein	D2JLF9	Staphylococcus_phage	0.0e+00	95.6
1959808:1959822	attL	NA	NA	NA	NA
WP_001154314.1\|1961119_1962610_-\|tail	phage tail family protein	D2JLF8	Staphylococcus_phage	1.4e-295	99.0
WP_001133544.1\|1962609_1967259_-\|tail	phage tail tape measure protein	A0A1V0E5H1	Staphylococcus_phage	0.0e+00	94.8
WP_000571956.1\|1967315_1967438_-	hypothetical protein	D2JLF6	Staphylococcus_phage	2.6e-14	97.5
WP_000442599.1\|1967497_1967944_-	hypothetical protein	D2JLF5	Staphylococcus_phage	3.0e-71	98.6
WP_000570643.1\|1968008_1968962_-	Ig-like domain-containing protein	A7TWD0	Staphylococcus_phage	3.1e-174	99.4
WP_000611453.1\|1968962_1969343_-	hypothetical protein	Q9MBP5	Staphylococcus_prophage	1.0e-67	99.2
WP_000501245.1\|1969339_1969717_-	HK97 gp10 family phage protein	D2JLF2	Staphylococcus_phage	6.9e-61	99.2
WP_025174659.1\|1969716_1970052_-\|head,tail	head-tail adaptor protein	A7TWC7	Staphylococcus_phage	7.4e-59	98.2
WP_001177485.1\|1970038_1970371_-\|head,tail	phage head-tail connector protein	D2JLF0	Staphylococcus_phage	1.2e-56	98.2
WP_001252099.1\|1970379_1970538_-	hypothetical protein	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
WP_000849948.1\|1970573_1971821_-\|capsid	phage major capsid protein	Q8SDK8	Staphylococcus_phage	2.5e-208	97.1
WP_000032523.1\|1971908_1972493_-\|head,protease	HK97 family phage prohead protease	D2JLE7	Staphylococcus_phage	2.9e-106	99.5
WP_000511060.1\|1972485_1973736_-\|portal	phage portal protein	D2JLE6	Staphylococcus_phage	1.4e-235	99.3
WP_000365298.1\|1973741_1973942_-	hypothetical protein	A0A1P8L6D3	Staphylococcus_phage	4.9e-26	97.0
WP_000133309.1\|1973955_1975650_-\|terminase	phage terminase family protein	D2JLE4	Staphylococcus_phage	0.0e+00	99.8
WP_000919023.1\|1975652_1976120_-\|terminase	phage terminase small subunit P27 family	D2JLE3	Staphylococcus_phage	4.8e-80	98.1
WP_001803930.1\|1976248_1976593_-	HNH endonuclease	D2JLE2	Staphylococcus_phage	1.0e-63	97.4
WP_000406189.1\|1976608_1977061_-	nucleoside triphosphate pyrophosphohydrolase family protein	D2JLE1	Staphylococcus_phage	3.9e-79	98.7
WP_000282752.1\|1977175_1977637_-	hypothetical protein	D2JLE0	Staphylococcus_phage	1.1e-68	100.0
WP_000265040.1\|1977659_1977860_-	DUF1514 family protein	D2JLD9	Staphylococcus_phage	2.4e-28	98.5
WP_001005261.1\|1977859_1978510_-	hypothetical protein	D2JLD8	Staphylococcus_phage	3.8e-115	98.1
WP_000595250.1\|1978668_1978818_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	1.4e-17	98.0
WP_000195765.1\|1978814_1979021_-	DUF1381 domain-containing protein	A0A2D1G5K8	Staphylococcus_phage	4.3e-17	69.1
WP_000185673.1\|1979057_1979570_-	dUTP diphosphatase	B2ZYX2	Staphylococcus_phage	9.7e-58	69.3
WP_000066809.1\|1979562_1979805_-	hypothetical protein	Q8SDV4	Staphylococcus_phage	7.3e-32	91.2
WP_001065204.1\|1979804_1980047_-	DUF1024 family protein	Q9G013	Staphylococcus_virus	7.1e-35	96.2
WP_001105591.1\|1980039_1980324_-	hypothetical protein	Q9MBR2	Staphylococcus_prophage	2.8e-43	94.6
WP_101305153.1\|1980338_1980581_-	hypothetical protein	A0A2I6PDB4	Staphylococcus_phage	8.1e-39	95.0
WP_101305154.1\|1980895_1981081_-	DUF3113 family protein	M9NSS9	Staphylococcus_phage	5.1e-25	95.1
WP_001123688.1\|1981501_1981723_-	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_001132243.1\|1982708_1983065_-	hypothetical protein	M9NS37	Staphylococcus_phage	8.2e-64	100.0
WP_101305155.1\|1984147_1984495_-	single-stranded DNA-binding protein	A0A0E3XC62	Staphylococcus_phage	4.0e-55	97.3
WP_001043063.1\|1984494_1985133_-	ERF family protein	Q9MBS2	Staphylococcus_prophage	1.7e-115	100.0
WP_000002514.1\|1985132_1985612_-	siphovirus Gp157 family protein	R4IFK3	Staphylococcus_phage	5.8e-81	98.7
WP_000291086.1\|1985626_1985887_-	DUF1108 family protein	Q4ZBM7	Staphylococcus_phage	1.7e-42	97.7
WP_000048119.1\|1985980_1986142_-	DUF1270 family protein	A0A059T7J6	Staphylococcus_phage	4.3e-20	98.1
WP_001124184.1\|1986154_1986418_-	helix-turn-helix domain-containing protein	B7T0G2	Staphylococcus_virus	1.1e-44	98.9
WP_001202628.1\|1986562_1986760_-	hypothetical protein	A7TWF5	Staphylococcus_phage	1.9e-22	93.8
WP_101305156.1\|1986775_1987525_-	phage antirepressor KilAC domain-containing protein	A0A1W6JPN2	Staphylococcus_phage	2.9e-135	99.2
WP_000498529.1\|1987585_1987828_+	hypothetical protein	Q4ZCA7	Staphylococcus_virus	2.8e-15	50.0
WP_001025399.1\|1987775_1988084_-	hypothetical protein	NA	NA	NA	NA
WP_000854067.1\|1988099_1988369_-	helix-turn-helix transcriptional regulator	H9A0Y0	Staphylococcus_phage	1.1e-39	95.5
WP_001031451.1\|1988502_1989216_+	helix-turn-helix transcriptional regulator	M9NUL0	Staphylococcus_phage	1.0e-126	96.6
WP_001049401.1\|1989227_1989374_+	hypothetical protein	U5U441	Staphylococcus_phage	4.3e-19	100.0
WP_000100503.1\|1989370_1989556_+	hypothetical protein	A0A1X9H0K5	Staphylococcus_phage	1.1e-24	100.0
WP_000439124.1\|1989591_1990575_+	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	9.9e-168	92.0
WP_001145714.1\|1990753_1991800_+\|integrase	site-specific integrase	Q4ZDS8	Staphylococcus_virus	8.0e-200	98.9
1993357:1993371	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP025395.1|WP_000809858.1|1867808_1867994_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP025395.1|WP_000809858.1|1867808_1867994_-|hypothetical-protein

1867808_1867994_-

61 aa aa

1819238-1886383

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP025395_3	Orphan	3.1\|2001827\|33\|NZ_CP025395\|CRISPRCasFinder	2001827-2001859	33	1843293-1843325	0

1. spacer 3.1|2001827|33|NZ_CP025395|CRISPRCasFinder matches to NZ_CP025395 position: 1843293-1843325, mismatch: 0

ttgcctgtagaaattggtgttccaatttctcta	CRISPR spacer
ttgcctgtagaaattggtgttccaatttctcta	Protospacer
*********************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP025395

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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