CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015167	Cellulophaga lytica DSM 7489, complete sequence	3 crisprs	DEDDh,WYL,cas3,PrimPol	0	2	1	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015167_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015167_1

186919-187288

Orphan

Consensus_repeat	Method
AGTATCTGGTTCTGCAGATATTAA	CRISPRCasFinder
TCTGGNTCTGGAGANATN	CRT
TAAAAGCTAGAGTATCTGGTTCTGGAGA	PILER-CR

6 spacers

The CRISPR arrays of NC_015167_1

>merge|NC_015167|1|186919-187288|CRISPRCasFinder,CRT,PILER-CR
ATTATCTGGCTCTGGAGATATTATTGGCAAAACAACATTAGTAAGTAATACTTTTAAAACTAGTATATCTGGCTCAGGAGACATAAACCTAAAAGTTAAAACAAAAGAACTAAAAGCTAGTATGTCTGGATCTGGAGACATAAATCTTAGTGGCTCTGCTACCGACTTTACTGTTAGAGTTTCTGGTTCTGGAGACATCTCTGCATATGATTTAGAAGCAGACTATGTAAAAGCATTAGTATCTGGTTCTGCAGATATTAAGGTAACTGCAAAAGAAACTATAGACGCTAGAGTATCTGGTTCTGGAGATATTAAATACAGAGGTAATCCTAAAAAAATAGAAAGTAAAACCTCTGGTTCTGGTGGTGTT

>NC_015167|1|1|186919-187233|CRISPRCasFinder
ATTATCTGGCTCTGGAGATATTAT	TGGCAAAACAACATTAGTAAGTAATACTTTTAAAACTAG
TATATCTGGCTCAGGAGACATAAA	CCTAAAAGTTAAAACAAAAGAACTAAAAGCTAG
TATGTCTGGATCTGGAGACATAAA	TCTTAGTGGCTCTGCTACCGACTTTACTGTTAG
AGTTTCTGGTTCTGGAGACATCTC	TGCATATGATTTAGAAGCAGACTATGTAAAAGCATT
AGTATCTGGTTCTGCAGATATTAA	GGTAACTGCAAAAGAAACTATAGACGCTAG
AGTATCTGGTTCTGGAGATATTAA

>NC_015167|1|1|186923-187288|CRT
TCTGGCTCTGGAGATATT	ATTGGCAAAACAACATTAGTAAGTAATACTTTTAAAACTAGTATA
TCTGGCTCAGGAGACATA	AACCTAAAAGTTAAAACAAAAGAACTAAAAGCTAGTATG
TCTGGATCTGGAGACATA	AATCTTAGTGGCTCTGCTACCGACTTTACTGTTAGAGTT
TCTGGTTCTGGAGACATC	TCTGCATATGATTTAGAAGCAGACTATGTAAAAGCATTAGTA
TCTGGTTCTGCAGATATT	AAGGTAACTGCAAAAGAAACTATAGACGCTAGAGTA
TCTGGTTCTGGAGATATT	AAATACAGAGGTAATCCTAAAAAAATAGAAAGTAAAACC
TCTGGTTCTGGTGGTGTT

>NC_015167|1|1|187029-187227|PILER-CR
TAAAAGCTAGTATGTCTGGATCTGGAGA	CATAAATCTTAGTGGCTCTGCTACCGACTTTACTGT
TAGAGTTTCTGGTTCTGGAGACATCTCT	GCATATGATTTAGAAGCAGACTATGTAAAAGC
ATTAGTATCTGGTTCTGCAGATATTAAG	GTAACTGCAAAAGAAACTATAGACGC
TAGAGTATCTGGTTCTGGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015167.1\|WP_013619776.1\|192909_194301_+\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235798
NC_015167.1\|WP_013619760.1\|177700_178240_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	unknown	unknown	gnl\|CDD\|235365
NC_015167.1\|WP_013619761.1\|178450_180283_-\|30S-ribosomal-protein-S1	unknown	unknown	gnl\|CDD\|235775
NC_015167.1\|WP_013619770.1\|188778_189588_-\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|320690
NC_015167.1\|WP_013619777.1\|194386_194677_+\|DUF3817-domain-containing-protein	unknown	unknown	gnl\|CDD\|378962
NC_015167.1\|WP_013619763.1\|180993_181686_-\|(d)CMP-kinase	unknown	unknown	gnl\|CDD\|234579
NC_015167.1\|WP_013619774.1\|191319_191847_+\|DUF1572-family-protein	unknown	unknown	gnl\|CDD\|311521
NC_015167.1\|WP_013619759.1\|176763_177690_-\|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234849
NC_015167.1\|WP_013619772.1\|190418_190907_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|376583
NC_015167.1\|WP_013619764.1\|181740_184185_-\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NC_015167.1\|WP_013619765.1\|184403_184961_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NC_015167.1\|WP_013619771.1\|189760_190294_+\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_013619758.1\|176424_176757_-\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_042256468.1\|191850_192750_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293840
NC_015167.1\|WP_013619769.1\|187374_188694_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341035
NC_015167.1\|WP_013619778.1\|194685_195414_-\|diphthine--ammonia-ligase	unknown	unknown	gnl\|CDD\|238952
NC_015167.1\|WP_013619773.1\|190906_191317_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|376583
NC_015167.1\|WP_013619762.1\|180555_180936_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|236880
NC_015167.1\|WP_013619767.1\|185486_186563_+\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_013619766.1\|184957_185506_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015167.1\|WP_013619776.1\|192909_194301_+\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_015167.1\|WP_013619760.1\|177700_178240_-\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	gnl\|CDD\|235365	PRK05205, PRK05205, bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR.	5.85142e-54
NC_015167.1\|WP_013619761.1\|178450_180283_-\|30S-ribosomal-protein-S1	gnl\|CDD\|235775	PRK06299, rpsA, 30S ribosomal protein S1; Reviewed.	0
NC_015167.1\|WP_013619770.1\|188778_189588_-\|M48-family-metallopeptidase	gnl\|CDD\|320690	cd07331, M48C_Oma1_like, Peptidase M48C, integral membrane endopeptidase. This subfamily contains peptidase M48C Oma1 (also called mitochondrial metalloendopeptidase OMA1) protease homologs that are mostly uncharacterized. Oma1 is part of the quality control system in the inner membrane of mitochondria, with its catalytic site facing the matrix space. It cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Oma1 can cleave the misfolded multi-pass membrane protein Oxa1, thus exerting a function similar to the ATP-dependent m-AAA protease for quality control of inner membrane proteins; it cleaves a misfolded polytopic membrane protein at multiple sites. It has been proposed that in the absence of m-AAA protease, proteolysis of Oxa1 is mediated by Oma1 in an ATP-independent manner. Oma1 is part of highly conserved mitochondrial metallopeptidases, with homologs present in higher eukaryotes, eubacteria and archaebacteria, all containing the zinc binding motif (HEXXH). It forms a high molecular mass complex in the inner membrane, possibly a homo-hexamer.	7.57882e-91
NC_015167.1\|WP_013619777.1\|194386_194677_+\|DUF3817-domain-containing-protein	gnl\|CDD\|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	1.3469e-29
NC_015167.1\|WP_013619763.1\|180993_181686_-\|(d)CMP-kinase	gnl\|CDD\|234579	PRK00023, cmk, (d)CMP kinase.	2.93921e-112
NC_015167.1\|WP_013619774.1\|191319_191847_+\|DUF1572-family-protein	gnl\|CDD\|311521	pfam07609, DUF1572, Protein of unknown function (DUF1572). These proteins, from several diverse bacteria, share a short conserved sequence towards their N termini.	1.60849e-79
NC_015167.1\|WP_013619759.1\|176763_177690_-\|aspartate-carbamoyltransferase-catalytic-subunit	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	3.50114e-179
NC_015167.1\|WP_013619762.1\|180555_180936_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	4.99993e-24
NC_015167.1\|WP_013619764.1\|181740_184185_-\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NC_015167.1\|WP_013619765.1\|184403_184961_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	7.21134e-38
NC_015167.1\|WP_013619769.1\|187374_188694_-\|MFS-transporter	gnl\|CDD\|341035	cd17482, MFS_YxiO_like, Bacillus subtilis YxiO, Listeria monocytogenes BtlA, and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis MFS-type transporter YxiO, and similar proteins including Listeria monocytogenes BtlA. The function of B. subtilis YxiO is still unknown, and L. monocytogenes BtlA is a putative secondary transporter involved in bile tolerance and general stress resistance. This family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.23862e-93
NC_015167.1\|WP_042256468.1\|191850_192750_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	4.8592e-65
NC_015167.1\|WP_013619778.1\|194685_195414_-\|diphthine--ammonia-ligase	gnl\|CDD\|238952	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins is predicted to bind ATP. This domainhas a strongly conserved motif SGGKD at the N terminus.	3.33522e-59
NC_015167.1\|WP_013619773.1\|190906_191317_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|376583	pfam01641, SelR, SelR domain. Methionine sulfoxide reduction is an important process, by which cells regulate biological processes and cope with oxidative stress. MsrA, a protein involved in the reduction of methionine sulfoxides in proteins, has been known for four decades and has been extensively characterized with respect to structure and function. However, recent studies revealed that MsrA is only specific for methionine-S-sulfoxides. Because oxidized methionines occur in a mixture of R and S isomers in vivo, it was unclear how stereo-specific MsrA could be responsible for the reduction of all protein methionine sulfoxides. It appears that a second methionine sulfoxide reductase, SelR, evolved that is specific for methionine-R-sulfoxides, the activity that is different but complementary to that of MsrA. Thus, these proteins, working together, could reduce both stereoisomers of methionine sulfoxide. This domain is found both in SelR proteins and fused with the peptide methionine sulfoxide reductase enzymatic domain pfam01625. The domain has two conserved cysteine and histidines. The domain binds both selenium and zinc. The final cysteine is found to be replaced by the rare amino acid selenocysteine in some members of the family. This family has methionine-R-sulfoxide reductase activity.	1.14314e-73
NC_015167.1\|WP_013619772.1\|190418_190907_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|376583	pfam01641, SelR, SelR domain. Methionine sulfoxide reduction is an important process, by which cells regulate biological processes and cope with oxidative stress. MsrA, a protein involved in the reduction of methionine sulfoxides in proteins, has been known for four decades and has been extensively characterized with respect to structure and function. However, recent studies revealed that MsrA is only specific for methionine-S-sulfoxides. Because oxidized methionines occur in a mixture of R and S isomers in vivo, it was unclear how stereo-specific MsrA could be responsible for the reduction of all protein methionine sulfoxides. It appears that a second methionine sulfoxide reductase, SelR, evolved that is specific for methionine-R-sulfoxides, the activity that is different but complementary to that of MsrA. Thus, these proteins, working together, could reduce both stereoisomers of methionine sulfoxide. This domain is found both in SelR proteins and fused with the peptide methionine sulfoxide reductase enzymatic domain pfam01625. The domain has two conserved cysteine and histidines. The domain binds both selenium and zinc. The final cysteine is found to be replaced by the rare amino acid selenocysteine in some members of the family. This family has methionine-R-sulfoxide reductase activity.	2.07245e-79

>NC_015167.1|WP_013619767.1|185486_186563_+|hypothetical-protein
MKTLHYKIITLLLLTIPFLSTANNDKGKYTKEKTIKKNFTVNANALLKVNNKYGNLNITSWDQNRIEIEVHIKTSGNNEEKVQRKLDNITVNFEGSSSTVSAKTNIAKSSSWGWGNSNNVNMQINYTIKLPVKNNIDLTNDYGSITLDRIDGHATINCDYGRLDIGELRGRNNNLNFDYTSKSEIDYVNSAKINADYSGFTITKAGNLILNTDYTSASIINAQDIDYTSDYGSISVNQAKNIKGSGDYISIKLGKVNGNVTLDADYGSIKISELTENCGNVIINADYTGVKVGYNNNYNFKFNLKSSYGGISGVDNCNLSLKEVKNSQKNYKGSCGSENSNNFVNITTEYGSISIHKN
>NC_015167.1|WP_013619766.1|184957_185506_+|hypothetical-protein
MKNNIDIDNLFKELKGSFDTQEPSTTHTANFIEKLNTSNKRHNKRSWKPFAIAASIAFLCAIGFSYFYQKQTTNEQIAEIAPEITETKFYFASLINNQVNELKKETSPSTKKIIDDTLLQLTKLENDYKKLEQNLVNGGNTKLILSAIITNYQTRIDLVKDVMEQIDTIKNLKNYNDENFTL
>NC_015167.1|WP_013619765.1|184403_184961_+|RNA-polymerase-sigma-factor
MSQQKEHINTLLLQCKEGKQSAQLEIYNRYYKAMHNTAYRIVKHSAEAEDIMQESFLSAFTKLHTYKGEVAFGAWLKRIVINNSIYQYRKQQKNTEVALDDIMYRVKDNDSSTIDNGETQLKAQKVMDAMKQLKDNYRISLTLHLIEGYDYEEISEIMNISYANCRTTISRAKESLRKQLTSACI
>NC_015167.1|WP_013619764.1|181740_184185_-|endopeptidase-La
MRDSEFDNLALQGINEEAELIPLLTPEDEEEMSKEQLPEMLPILPLRNTVLFPGVVVPITAGRDASIHLIKDANEGSKVIGVVAQKDEQTENPGIDDIHTLGTVARILRVLKMPDGNTTVIIQGKKRFEVAEVLTEKPYMTATVREASEVRAEEDTPEFKAIIESIKDMALKVISESPNIPSEASFAIKNIESNSFLINFVSSNLRLPVKDKQELLEIENLKERALATLKFMNVEMQKLQLKNDIQSKVRTDMDRQQREYFLHQQMRTIQEELGGGATAEDELTELREKAKDKKFTKKEREYFNKELSKMQRMNPQVAEYAIQRNYLDFFVSLPWGEYSTDKFDLKAAQKILDRDHYGLEDVKKRIIEYLAVLKLRNDMKSPILCLYGPPGTGKTSLGKSIAEALGRSYVRMSLGGLRDESEIRGHRKTYIGAMPGRVLKNIKKAEHSNPVFVLDEIDKLSNSHQGDPSSAMLEVLDPEQNNEFYDNFLEVGYDLSKVMFIATANNLGAIQPALRDRMEIINVSGYTIEEKVEIAKRHLLPKQLKEHGLKPKDLKIGKAQLEKIVEGYTRESGVRTLDKQIAKMVRYAAKSIATEEEYEVKVTNEIVEKVLGPARLERDKYENNDVAGVVTGLAWTSVGGDILFIESILSKGKGAMNITGNLGKVMKESATIALEYIKSNADYFGIKDDIFDKYNVHIHVPEGATPKDGPSAGVTMLTSLVSLFTQRKVKKSLAMTGEITLRGKVLPVGGIKEKILAAKRARIKEIILCEDNRKDILEIKEEYLKGLTFHYVTDMSQVIDIAVTNQKVKNPKKI
>NC_015167.1|WP_013619763.1|180993_181686_-|(d)CMP-kinase
MKKITIAIDGYSSTGKSTIAKQLAKALGYVYVDTGAMYRAVTLYAIRKGFVSETSEDFESLIAALPSISLKFVHNEDLGFSEMYLNNENVEKEIRTLEVSKQVSKVAAVKEVRTKLVEMQKAMGKEKGIVMDGRDIGSVVFPDAEFKVFMTASPETRAHRRYKELLDRGDDVTYDEVLKNVRSRDYIDSNRKESPLILAEDAIEFDNSDMGLIEQFERMHNYALRIIEKQ
>NC_015167.1|WP_013619762.1|180555_180936_+|LysM-peptidoglycan-binding-domain-containing-protein
MSVKAKYQSVLDLGEKLAIKDGDVTEESGVLKIKGQAATQYEKNLIWDKIKEIGGDSPADVKANITVADESVYHRHTVQGGESLSKIAKHYYGDPMKYKQIFEANTNLLKNPDVIHPDQVLVIPNL
>NC_015167.1|WP_013619761.1|178450_180283_-|30S-ribosomal-protein-S1
MAEEKNNAQVEESTQAPEVKTATPKQDPKEFLASFDWDKYEEGIERVDDSKLEEFEAMVAENFVDTADEEVVTGKVVHLTEREAIIDINAKSEGVISLNEFRYNPDLKVGDNVEVLIDIREDKSGQLVLSHRKARTIKAWDRVNNACEKEEIVNGFVKCRTKGGMIVDVFGIEAFLPGSQIDVKPIRDYDQYVGKNMEFKVVKINQEFKNVVVSHKALIEADIEEQKKEIIGQLEKGQVLEGVVKNITSYGVFIDLGGVDGLIHITDLSWSRINHPNEVVELDQKMNVVILDFDDNKSRIQLGLKQLEKHPWEALSEDMKVGDKVKGKVVVIADYGAFIEVAEGVEGLVHVSEMSWSTHLRSAQDFVKVGDEIEAQILTLDRDDRKMSLGIKQLTPDPWTDITSKYPVHSRHKGIVRNFTNFGVFVEMEEGIDGLIYISDLSWTKKIKHPSEFVTVGETLEVEVLELDVDARKLSLGHKQTTENPWDKYETEFALDSVHKGTVDEIVDKGAIVNFNEDIAAFVPTRHLEKEDGKKIAKGEEAEFKIIEFNKEFKRVVASHTAIFREEEQRNVKAAVKRQSAAADEAKPTLGDANEALQALKDKMDAANKK
>NC_015167.1|WP_013619760.1|177700_178240_-|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR
MSKKVLLSSKEIQIILHRLACQLLENHTDFKDTVLIGLQPRGTYLAKRLTTILTQEYGVKEINLGSLDITFYRDDFRRGEKTLEASKTHINFLVEDKKVVFIDDVLYTGRSIRSALTAIQSFGRPAEIELLTLIDRRFSRHLPIQPNYRGRQVDAINEEKVQVLWQENDGQDIVYLINE
>NC_015167.1|WP_013619759.1|176763_177690_-|aspartate-carbamoyltransferase-catalytic-subunit
MSELSVNHLLGIKYLNKNDINLIFETADHFKEVINRSIKKVPSLRDITIANIFFENSTRTKLSFELAEKRLSADVINFSASQSSVKKGETLIDTVNNILSMKVDMVVMRHPNPGAGVFLSKHVKAAIVNAGDGAHEHPTQALLDSYSIREKLGDVGGKNVVIVGDILHSRVALSNILALKLQGANVKVCGPKTLIPKHIESLGVTVETDLRKALNWCDVANMLRVQNERMDISYFPSTREYTQQFGVNKALLQSLDKEIVIMHPGPINRGVEITSDVADSNQSIILDQVENGVAVRMAVLYLLASKIK
>NC_015167.1|WP_013619758.1|176424_176757_-|hypothetical-protein
MVFDKDGTTTIVDQENISLAKFLENLNNAYEKIKNDNIIVNLFSFTALTSSDVLEFLDLSNTHRGSNKSFVLVTNKVSYDDVPEEICVVPTIKEARDIIEMEEIERDLGI
>NC_015167.1|WP_013619769.1|187374_188694_-|MFS-transporter
MTSIALVKGSKKLLNAWAFYDWANSVYSLVIASAIFPIFYGALFRAANIEKVTVFGGEIARAPLISYTTSLAFVFIAIITPLISGVADYLGNKRMFMKFFCYLGGVSCIGLYWFSLENIYFGLVCFFMGLVGFWVSFAINNSYLPDVAHPEQMDAISAKGFSMGYAGSVLLLLFNLLMVMRPEIFGIETDTNGIAELKAMKYSFVTVGIWWIIFSQYTFYYLPKGNKQEGDRSNVILNGFKELKGVWGQLGSQVKLKRYLIAFFVYSMAVQTVMLIATYFGEEEIAWGTDKERTTGLIVSILVIQIVAILGALVTAAASKKFGNVKTLAVVNILWVVICVYAFFMVTPIDFYIGAGCVGLVMGGIQALSRSTYSKFLPNTKDTTSFFSFYDVAEKIGIVIGTFLYGFVAQVTGSMRNAIVFLAIFFIAGVVLLLRVNKK
>NC_015167.1|WP_013619770.1|188778_189588_-|M48-family-metallopeptidase
MRKIFLVLTIFIAVSACKTNPFTGKKTLNMYPNSSIFPTAFAQYDQFLNENKTITGTSEAKMITSVGQRIASAAERWLTANGYPGYLKDYKWEYNLVDDATVNAWCMPGGKIVFYTGILPICQDETGIAVVMGHEVAHALADHGAQRMSAGQLQQIGAVAGNVLIKDEGTKNTFNQAYGIGSQVGVMLPFSRGHETEADRIGLQIMAIAGYNPDEAAELWKRMKANSGGQSQPEFMSTHPSNDTRINNLTQWAPAAKEEAKKFGVTSFK
>NC_015167.1|WP_013619771.1|189760_190294_+|hypothetical-protein
MKKITLAVAAIFAIILTACSGSDGIDGVDGLDGVNITGSIYEVSGTFSDENNYELTFEFPNTVEVFESDVVLVYILWEQVDGTDGQPIDVWRLMPQTRLLDQGTLIYNYDHTFADARFFLESDFELGTLNTADTANQIFRVAILPAEAVNGKLDTGNINDVMGILDTKEENIIHVSL
>NC_015167.1|WP_013619772.1|190418_190907_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MYKKLLILSVVALFLSCKGNSQKTKEATKKQTLAKVEKTDAEWKAQLTPLQYNVLRKAGTERAFSSELLNIKEKGIYSCAACNTPLFKSEHKFKSGTGWPSFDRTIEGNVAFDVDYKIGYKRTEEHCAVCGGHLGHVFNDGPKTTGERHCINGAALKFTPTK
>NC_015167.1|WP_013619773.1|190906_191317_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MSKKYTVEKTEEEWKALLPEQSYNVLRNKGTEYPHTGEFNLHFKDGSYNCKGCNAKLFEADHKFESGCGWPSFDEAVEGAIEYIKDTSHGMTRVETVCANCGGHLGHVFDDGPQETTGQRYCINSASLNFNPSLKK
>NC_015167.1|WP_013619774.1|191319_191847_+|DUF1572-family-protein
MSFVDDYKESMLFEFNRNKTMAEKTFDQLTNEDLHWTYGEADNSIAIIVKHMVGNMLSRWTNFFTEDGEKEWRNRESEFVAPYQNKEEMLLHWNKGWDCLFTAIDNINEDNFNTKIKIRAVEHSVMAAVSRQLAHYAGHIAQIAYVGRMLKGKKWQSLSIPTGKSEEFNKKMFGK
>NC_015167.1|WP_042256468.1|191850_192750_-|MBL-fold-metallo-hydrolase
MKTTKFAFLLPFLMFAAIVQSQSNDVKMQVDKLTPQMYMLTGQGGNIGVFVGEEYVLMIDDQFSRLSTKIKQAIKSITTKPIVYLLNTHMHGDHTGGNANFNNQTTTIIAHQKVRERLVNENEKALLSKKIDSVTAHKKLPEITFSDTMLLYDADETIMAIHVHNAHTDGDAQIYFSKNNVLHMGDTYFSGKYPYIDLNRGGSVGGYINALKKAAILANEDTKIIPGHGKLSNKKELESYILMLETIYVNVKKEIGAGKSLEQVIANKQITANYDATYAWSFISAEKIRETFYKSLMNK
>NC_015167.1|WP_013619776.1|192909_194301_+|dihydrolipoyl-dehydrogenase
MSNFDVIVLGSGPGGYVTAIRASQLGLKTAIVEKESLGGVCLNWGCIPTKALIKSAQVFEYLKHAGDYGLNAENVDKDFGAIIKRSRGVAEGMSKGVQFLMKKNKIEVIKGYGTLKAGKKIAVKDADGKETEYSADHIVVATGARSRELPSLPQDGKKIIGYREAMSLPEQPKKMVVVGSGAIGMEFAYFYNSIGTEVTVVEYLPNVVPVEDQDISKQLERSFKKAGIKVKTSSEVTKVDTSGNGVSVYVKTSKGEEIIQADVVLSAVGIKTNIENIGLENVGIATDRDKIMVNDYYQTNIPGYYAIGDVTPGPALAHVASAEGILCVEKIAGMHVEPIDYGNIPGCTYCIPEVASVGLTEKQAKEKGFDLKIGKFPFSASGKAKASGTPDGFVKVIFDAKYGEWLGCHMIGAGVTDMIAEAVVARKLETTGHEILKAIHPHPTMSEAVMEAVADAYDEVIHL
>NC_015167.1|WP_013619777.1|194386_194677_+|DUF3817-domain-containing-protein
MIKAFRLIAILEGISYLLLFGVGMPLKYMADIKAPNIYIGNAHGVLFIAYAILAFFVCRHLKWGIKRYAILFIASLLPFGTFYIEEKYFSPKALKA
>NC_015167.1|WP_013619778.1|194685_195414_-|diphthine--ammonia-ligase
MHKTYFNWSSGKDSALALYKMQQSNAYKVDRLVTSVNSTFNRVSMHGLRLPLLEAQAKAIGLPLQTIMLNADVSMSSYNEVMKTTMQGLILKGYTHAVFGDIFLEDLKKYREDKLKEVGVKGVFPLWKQDTKALLKELLQLGFKAITVCVNAKLLDESFVGREVDESFFNDLPENVDPCGENGEFHTFVYDGPIFKQPVSFTVGEKVKKGYAPTTNKDDNCFKKDEDTTWDTSFWYCDLLPK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_015167_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015167_3

2678599-2678703

Unclear

Consensus_repeat	Method
GTTGGTAAATCAGGTTAGTAAATAAATA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_015167_3

>merge|NC_015167|3|2678599-2678703|CRISPRCasFinder
GTTGGTAAATCTGGTTGGTGAATAAAAACATTGTCGTTATAGTATTTACAATAGTTGACAAGTTAAAAGAAGAAAAGGTTGGTAAATTCAGTTGGTGAATAAATG

>NC_015167|3|3|2678599-2678703|CRISPRCasFinder
GTTGGTAAATCTGGTTGGTGAATAAAAA	CATTGTCGTTATAGTATTTACAATAGTTGACAAGTTAAAAGAAGAAAAG
GTTGGTAAATTCAGTTGGTGAATAAATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015167.1\|WP_013621938.1\|2664691_2665069_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224218
NC_015167.1\|WP_013621953.1\|2691642_2692155_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NC_015167.1\|WP_013621936.1\|2662411_2662738_+\|YegP-family-protein	unknown	unknown	gnl\|CDD\|377831
NC_015167.1\|WP_013621943.1\|2669225_2672063_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|350769
NC_015167.1\|WP_013621939.1\|2665079_2665517_-\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|225876
NC_015167.1\|WP_013621944.1\|2672069_2676824_+\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_013621950.1\|2688586_2688859_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_015167.1\|WP_013621940.1\|2665497_2667927_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NC_015167.1\|WP_013621954.1\|2692151_2692304_-\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_013621946.1\|2678733_2685039_+\|DEAD/DEAH-box-helicase	cas3	cd09710_cas3_CAS-I-D	gnl\|CDD\|350681
NC_015167.1\|WP_169309926.1\|2685133_2687119_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223288
NC_015167.1\|WP_013621955.1\|2692879_2693815_+\|calcium/sodium-antiporter	unknown	unknown	gnl\|CDD\|223604
NC_015167.1\|WP_013621942.1\|2668934_2669207_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_015167.1\|WP_013621952.1\|2689982_2691254_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271185
NC_015167.1\|WP_013621945.1\|2676820_2678224_+\|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225420
NC_015167.1\|WP_013621956.1\|2693902_2694913_-\|glutamine-synthetase-beta-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|177922
NC_015167.1\|WP_013621941.1\|2667928_2668780_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|275263
NC_015167.1\|WP_013621948.1\|2687199_2687883_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|236153
NC_015167.1\|WP_013621951.1\|2689039_2689873_-\|RteC-domain-containing-protein	unknown	unknown	gnl\|CDD\|378161
NC_015167.1\|WP_013621937.1\|2663685_2664702_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015167.1\|WP_013621938.1\|2664691_2665069_-\|hypothetical-protein	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	0.00592972
NC_015167.1\|WP_013621953.1\|2691642_2692155_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	7.51867e-95
NC_015167.1\|WP_013621936.1\|2662411_2662738_+\|YegP-family-protein	gnl\|CDD\|377831	pfam07411, DUF1508, Domain of unknown function (DUF1508). This family represents a series of bacterial domains of unknown function of around 50 residues in length. Members of this family are often found as tandem repeats and in some cases represent the whole protein. All member proteins are described as being hypothetical.	2.66547e-20
NC_015167.1\|WP_013621940.1\|2665497_2667927_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	9.1834e-16
NC_015167.1\|WP_013621939.1\|2665079_2665517_-\|DUF1232-domain-containing-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	0.000217355
NC_015167.1\|WP_013621956.1\|2693902_2694913_-\|glutamine-synthetase-beta-grasp-domain-containing-protein	gnl\|CDD\|177922	PLN02284, PLN02284, glutamine synthetase.	2.17817e-132
NC_015167.1\|WP_013621950.1\|2688586_2688859_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.18442e-09
NC_015167.1\|WP_013621946.1\|2678733_2685039_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|350681	cd17923, DEXHc_Hrq1-like, DEAH-box helicase domain of Hrq1 and similar proteins. Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. Hrq1 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.21426e-55
NC_015167.1\|WP_169309926.1\|2685133_2687119_+\|AAA-family-ATPase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	2.63668e-15
NC_015167.1\|WP_013621955.1\|2692879_2693815_+\|calcium/sodium-antiporter	gnl\|CDD\|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	8.97616e-61
NC_015167.1\|WP_013621942.1\|2668934_2669207_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.75739e-08
NC_015167.1\|WP_013621952.1\|2689982_2691254_-\|site-specific-integrase	gnl\|CDD\|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.82123e-57
NC_015167.1\|WP_013621945.1\|2676820_2678224_+\|putative-DNA-binding-domain-containing-protein	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	3.65983e-97
NC_015167.1\|WP_013621948.1\|2687199_2687883_-\|ATP-binding-protein	gnl\|CDD\|236153	PRK08116, PRK08116, hypothetical protein; Validated.	3.54437e-06
NC_015167.1\|WP_013621941.1\|2667928_2668780_-\|radical-SAM-protein	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	3.44684e-25
NC_015167.1\|WP_013621943.1\|2669225_2672063_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	8.25432e-51
NC_015167.1\|WP_013621951.1\|2689039_2689873_-\|RteC-domain-containing-protein	gnl\|CDD\|378161	pfam09357, RteC, RteC protein. Human colonic Bacteroides species harbor a family of large conjugative transposons, called tetracycline resistance (Tcr) elements. Activities of these elements are enhanced by pregrowth of bacteria in medium containing tetracycline, indicating that at least some Tcr element genes are regulated by tetracycline. An insertional disruption in the rteC gene abolished self-transfer of the Tcr element to Bacteroides recipients, indicating that the gene was essential for self-transfer.	9.30356e-86

>NC_015167.1|WP_013621945.1|2676820_2678224_+|putative-DNA-binding-domain-containing-protein
MITDKDIKSIAASGEGYNAEFKVSAPANVRKLTEEICAFANASGGVLLIGVDDNNVIQGATIDNAKRSAIHNSIGEISPAINCDVYAVDVDGSEIWVIEIPSGTQKPYVLSGAIYVRNGPNSQKVTTVEEMRDFFQQADRIYFDETPCPAFDIATGIHADNLNEFKAEANLSNAVPNEQIFKNLKLQDQNNAFKNGAVLFFGKEPQQYIDTALIRCVAFDGKDKRYIVDDKKFTGPLYVQYKDAIQWLKNKLDVRYEIEGSTGPREEIWEIPQTAFKEAIVNALAHRDYYDRGATITIELFDDRVEIANPGGLVSAVSSKDFGKRSHSRNPLVFGLFARMRMVEQIGSGIGRIKDLMKENDLQPPHFSFDGMFTVTLTRPFDFEKWIARWEKHLTDNRLEILRAVNENSKVTIGELASKIGISDTAIGKNMDVLKELGLLDREGTKGGNWKLLHILPENDDGVGKSG
>NC_015167.1|WP_013621944.1|2672069_2676824_+|hypothetical-protein
MIEFLENIGDYFSQHFFDEDFPKKVFDKSGYGADHIKEFTSKIAPLSEKYYKFKNDYLNLRRTKDKVKRTHDFHTQLLQALGYINGVRAYDEPVVMDDKKIIPIRYRFNKNDKPYLYIMEMQPMIQVGEVDADGLYEQSYIKEDWEKVLPDSWDGYDIRPEVIKEALSELFLLPEEERPVYLIMLAGPKIFLIQYEKWKFDSYLLFDLEELFTVTKTASNKNLLALFYALLAKKQFISETESVLVGLEEDAHKASYGVTVTLKSAVIYAVEALANEAIYYKSSQAKTLEAKKEIVTLLDNDNFARELKDECLEMVYRLLFLFYAESRADLEILPIKDSTYQKGYSLEMLRDLEMVPLTTDSSRNGYFFSESLWKLFDFLHTGSDLKDGFQMRPLDSPLFDNASLKQLKGIQFRNKILQEIVVRLSLSERTKNKGRGRISYANLGINQLGSVYESLLSYSGFFAREDLIEVKNAKDKNGTDGTFLVPKTRRDDFKESEILKHEEYPEQDVIIPKGHFVYRLNGRDRKNSASYYTPEVLTQTTVKYTLKGIIERLKEKQAIVDGVLTGEACADEILKLKILEPAMGAAAFHNEVINQLAVAYLELKENEEQAAGRKRITPGIYKDELQKVKAYIAANNVYGVDLNPTAVELGKLSLWLNCMHKNMETPFFAHRLGAGNAVVGAWLKVYNDKDCLEEFPVLANGKIGKKPIPKPWWDKAPKRVMWNKKGTLSRKQNQIYHFLLPDDNMVPSYGIKLLKNELTEVEQKAFKDWRNEFKKPLTRVELNRLEKISNVIDYLLEEHYKQQMGMVKDTASVYQVYGQPNPQTTTKGYDEKERLTDSRKDRSAPYFKLKMILDYWCSLWFWDVRDVRLLPNRTEWYNEVESILQIDSNELLADGSSQDIKDQIRKKARAGTLFDTSDRIDNIEQLAQQHRFFHNEIEFVEVFYERGGFDVIVGNPPWVSITMDEAGILSEKNPEIFIKKMSASQVKKLAPKILENDVKLNEDFKKEFIWAQSTKQFLGAIQNYPLLQGHRNNLYKSILTNTFDLSSENGSIGLIHPDGIYDNPKGQKLRKTLYKRLDYHFQFQNKLMLFSEIKDKIIYSINIYSSPSEINFKNINNLFSVSTIVNSFGHSGLGICGGLKEKNVLNNQFEWNTSPHKSRIVQIESKSLKILQELFEPGANYESAKLPSIHSEDILKILEKLKENGGTLSDIKFFSTDCWNEVNSQNQGVIEKKVHYPTLDNFEFIYSGPHFFTANPFYRNPQIMVNNHNDYDIINLNLIDQNFIPRTIFTRYEDSDLFKNRVVGLDNWIFTYRLAMGKMIDTMSERTLQSTIIAPYTSHTNSVISIQTKSEFELLQLSGLSFSLVMDFYIKSLGKSNIYDNTIRNLIFGLDDIFLIFLNSRTLLLNCLSSAYQSLWERNWNEDFKKDSWSKKDTRLKPFNDLTKEWKWETPLRNWFERRQALVEIDVITAMALGLSLEELILMYNVQFPVLQQNEDDTWYDATGNIVFTVSKGLVGVGLDRSGWNSIKDMKAGETYEHTITKSELYQGKTITYHAPFTKCDRVEDYKTAWAHFENIFKTEEAVV
>NC_015167.1|WP_013621943.1|2669225_2672063_+|DEAD/DEAH-box-helicase
MNNDTLTQQTKKVTPGIRISLRGEDFIVTNRERDIIDVEGISELVYGQSFKFDLRLEKNYKVIKPEETELKADTSAHYRQTKLFLETTFRNSSHYSEHIEIAHKAAIRGANYQFESTIKALKLPQPKILIADAVGLGKTVQVGIFLAELIRRGKGKKVLVVTPKSILSQFQQEIWARFAIPLVRLDSQGIAKIKIEIPSNKNPFDYYDKVIVSIDTLKNNAKFRHYLERVKWDVVAIDECHTVANVASQRGGLAKFLSERTEAMVLTSATPHNGKRENFANLIGMLDPTAIPFNGEFTKEAIQPLYVRRFKKDVEDEVGDAFRDRVTSKIDCPLNRDEEEALRIIQEFKKVAQEDSDGDYNFEALLFSIGLFKAYMSSPKACLETVIKRIEKNIDEEGVIEHLTELRVILQKIVDEKSDSKYNQLKFKLDQMGWKGKKNDERIIIFAERRATLNELEKNLTEDFGLKPKAVVQFNGSLTDTQQQDILEDFSKEDSEIRLFLASDAGSQGVNLHYFCNQMFNYDIPWSIITLDQRNGRIDRFGQKQTPFIYYLISDSKSEDVQGDIRIVEKLKEKEEEVHKSLGDAGSVMGFYDQQQETKLVEKAIATGDDSLLDTKNKDVIDDDWLSSLMEDTATTKEEIKKDEGFASFYPDDFTYYATLIDELKAEDERLIPRITIDREDKVVEIEQFEELSSKGVLYDMPKEAFPQKNETFNLTTDSEIVERSIIRARKKQNEWPNFQLLYDLNPIAKWMQYKLLAQVDRGKALVARLREPLPKNTAWFVFQGITSNQQGKPMFSKTFVIGKSFDGASVGNLETFNEFLNQFRLNDRLTELETTNEQLDKIKSLLPEAVKRGEQLYKYTLQGGLEDELEEKLESYQEKLESWLTASEAQMELKFGDETSGSFHKKKRQREVNYVKEQMDEFYNEFFQLENEPFLRVLAVFFNA
>NC_015167.1|WP_013621942.1|2668934_2669207_+|helix-turn-helix-transcriptional-regulator
MIGERIRTLREANDILLRQLAAKLDMDQALLSKMERGERSFRKEDIDALAKIFKQSKKELLTLWLADKILKTVGSEKFSKEALRLAIENV
>NC_015167.1|WP_013621941.1|2667928_2668780_-|radical-SAM-protein
MDQLNLFSEEEVKREKLGKTAIEYKAASSILTPASGFMADYDYTLNPYSGCSFGCTYCYAAFFSRNKEKMDGWGDWLTVKENALSLLKKKRKRPLIDKTIYLSSVTDPYQPVEKELELTRSILKELLDFHKVRLVIQTRSALVTRDIDLLQKYETLQVNMTVTTDSEKVRKVFEPFCTGNKQRIKAITEMHNAGIQSCITMTPLLPIENPVQFADDLLATGIKRFIIQPFHKDKGKFVRGTRNEALKILNEFNWSDEEYNRVLSVMREKIPNLGIGKTGFAPI
>NC_015167.1|WP_013621940.1|2665497_2667927_-|ATP-dependent-helicase
MYNNYLDWLENQRSILDELFARAGFTFYEKHKHLDNFSFDANETQKECYLLGTDRDLCYDRFTIGLSYSLWYQGKRTNAFISYFAKLLYEAREENEITLLDLGAGTGAVQLAISLCKIGLDQLFGKSPKITIINIDTSPFMLDYNRSYLWPEFIKSYEIAKDIKTIYSVNSWEQTDTSNFNNFWITASYLFDQSDNVQHLSDNLSKLVETFEPRFIICNTSKRKSYLMNKASVPIKNQNYEVLSIDMKHLFTGSLPSTLAVRRKIKEECGVQYNGMPVWQENWMSSIILRLATPGLSIPIESPSVDLFTPPLTVRRDIILSPEQKKAAEDDGRPTVIYGPAGCGKTVVITERIINILKNSSEKPIEEISILVTTFNKGLVSVIKSWLKELLSREKFKFIDRGDSLRVGESTKDTITIMHFDVLPTRLWSKISDAPTPFKNDKIQFDNYHLSVAARAINTIKKKYGITTNVYDHVLNDRYVIDEYHYVIYGQDIAEASIYAKARIKGRKRLERDGNSRKYLFESVVLYLELLGLNSSFVKRRHQFYKELKKSNKGFGFSHLIVDEFQDCTQTDYNIFYELLKNPNNLIICGDFAQAIHLGNVANIPRLSQEDMGRRKFIQLVGSYRLPYRISECLQNFSKNIVTEEDDIKNPLSPFKGAPPGARPILIKASNSKEMALKIKNAVSSYHQYDIFNFNVVPYDNILILEKDAELRNELALFRRGLSYDETILKVKGLEKKCVVWTARKNIEFSERIRHYVYTILTRTSGILIIALFGEECKEYKDIINEFDPERVIIWDQDTKNYLDENYKL
>NC_015167.1|WP_013621939.1|2665079_2665517_-|DUF1232-domain-containing-protein
MKTTSFKKFKFEDLLLNNTRDYQNKHSELIRSAPYIYQLLTSLLDVTDLSVANRSKIFTSIGYFLVPKDLYSEDEHGAIGYIDDILLAIFVIKEVETEIGFEQIERLYNQDLNNLDELLNSGIYDNAIKDYDELFQEVLEFVGFY
>NC_015167.1|WP_013621938.1|2664691_2665069_-|hypothetical-protein
MEDKKSEQNILEKAINYISKLSSSKKEKLMTILKKVNEVQSSNLTTKEKAKEIKRIMWSDQSTNSKLFIGAFLGAVTGFFIFGTGGIGIAALGTGVGVWGWLATAAGGAFISSLIHNYEKKENEN
>NC_015167.1|WP_013621937.1|2663685_2664702_-|hypothetical-protein
MKINSINEITQAIKNFDIAALKELLDDNKPYQDVPKSLFLEKLEKKFNQARRDDCHSFDDVFFGICESCNKGCEGMTFLSNSGYYLDLFIESKDEEFADDIYVCNKLTNFTDLEKSIDLGFSFRKDEYYNFKPTSKYLIIKKEYNELLNQISEIEKPIKVDKLLNWYYNNFNYLSETINGFGPFECFDYNLYNDAYSLVSKVERVFEITQVKEQAIESLVDYHNSSTERERLIWFFKNQENLYGSIYFEFSEKWKTDSIIFYEQEQVELELDITGYEYVIDYFLILDNLYDELIEKYKPIPVHFEGSKNGSIECSLENYLRLRNKYIDVVKKYGRKGY
>NC_015167.1|WP_013621936.1|2662411_2662738_+|YegP-family-protein
MSKFEVYQDARSEYRFRLKADNGQKILASEGYSAKAGCMNGIESVRKNSQDDKRYERLKASNGKHYFNLKASNGQVIGTSEMYESSSGMENGIASVTSNAPKATIEEV
>NC_015167.1|WP_013621946.1|2678733_2685039_+|DEAD/DEAH-box-helicase
MLPLLQANEIKQAVVDYLRSTFNFEDPLLDQSFEDFLLSEQKGMFKGPYMQLRLPFDKIATDGDRDAFAKALYVKPPFDPYHHQFLSFLKLSTRNGHKPEPVILTTGTGSGKTESFLFPLLDYCYQHRDKPGIKAIILYPMNALATDQARRIAEEINDFNDGELKGKIRAGLFIGEGKDKDGIRATRMSEDRIIEDRKTLVDAPPDILLTNFKMLDFALLQARFHNLWSHNFKNTDLLKFIVLDELHTYDGAKGSDVANLIRRLKLKLKLPKDQIVPVGTSATMGGGDQGKLELVDFFSKVFGVKVTTDAVIEEQRLEPDEFFDDTIEEPVIDVNQIQKCAFEENDTYLSYLERQLVFWGYAGLSPKDLGDALKKNKWFFDLLKITKSDVVVIKPKLKRWREKIGLELDDKEIHLLFSSLLALITYAKEQSGSKQFPFLYLQITYWLRSLSKIVRKLQPTAAFEWESDMNPNDPVKSLPPYFCRECGGSGWIGIKKEQNAHFEDDLSRTRQQLMAHSQNKNLYFISSLEDRKYQEVYASDYTHSGDAIDGYLHPHSLSIYDNYESNDYFKILGTRIVDGNRIDKICPHCNSRNTLALIGTGVPTLESIATAQVLATATDPTKDGQRKLLAFTNGVQDAAHQAGFIENRNFRFGMRHAIQAVLKDVKEPITLPQVYERFIEHWKEHSDDEETGNLDAYYYKFFPPDCDARLEISDYRNKDGKLSSVFDKEFSNRMSWEIWSEFSYSAMIGRTLEKTGASATYFDTAVMSEVYDQMKYWLDENKLGTAIDKEPFLKFLNGFLHRLRTKGGVDHKYLKKYRTERTNSYLIGHRGNVNKQYFLMKNFGPSSRLPKFLALANGANTRAFDVVQTTTKDNWFSAYFKKCFQEIIQEETVLINDFYAQLLDYLDANKILDKRVAAGVTNYGLSENSIYLSPNVVHYECSHCGNQINTGAAQASLVSGMKCLQYRCKGQYEAAENSQLDYYRMVYNRGRSLRIFAKDHTGLIDRNEREKLEYDFKRQPKQDSTNVLVATSTLEMGIDIGDLNVTFNSSLPPETANYLQRIGRAGRSSGTSMILNLAGRDAHDLYYFQDPQDMMSGQIKTPSCYLEAKDILKRHFMAFCFDHWASMDPEENNIPPMVRVLRLKSLKPGDPNFLFQKIATHIENNKTLLYDLFVEQYKEQLGDNSKSLASIFEDLSSGRFINRLTCLHKNLLDEIEYYQEKIKLVNKRLKALPETGNETVILKNEKRALSSAIYNINRRNVIEYLTNVGVLPNYAFPETGVTLNAQIKRKKEVDGKTEYKYEDFSEIVRPSSSALTELAPANIFYSQGHKLKSEGLEIKSQEDYEEHRFCSNCNHVKKEIDVEENEQSQCPVCGHGSWSSLNNRKFLVKLQGVLSVNDKERSKITDSSDDRERHFYQKSVHIKINQSSSQGAHVLKRVPFGIEFFQDVDYLEINTGIREEGFFGTREIEINGEKHPQVGFVVCKTCGKSTERSLSARELNNRDRAYHFPYCSNREVLYADQSDDVFNEIYLYRKFNTEALSILLPVEDFRSEERIALFKAGLKLGLKEYFKGRPDHILIRENEIFNKTTNRKDRYLVFYETIPGGTGYLSKLFDTTVFTKILEKAYERIAFCSCKQEGKDGCYRCIYTYGNQYERTILSRTEAEELFSNILEKTDEWNSIESLQNVSTFGNNEESDLEWKFKGLLEEFANKFSGSTFESDNEMGLKIYKLKLAYYGNEIVYKVYPQNLNRWLFGIEKKTRPDFVLKCVGLTKNGKKFTLDELETIKDIVIYLDGYEYHASENHSDRFPKDLEIRNSIINSGRYNQWVFTWSDFAESIFNDKDAIGLKQDEKFIVGKFFLKHSSFKEYDFRDVYYNNNATRFFQLLINPITVVDNKNWSSLAVFSFQSKMMGVSYSPENVEQIIETRSIKDIEKGTLKLTNYIHADDLQLKDEASFGLFIRPEDFKLKGYGYYKAVPFWDKENWALFWRFYNLTQFHNIEVYSFDKEIKKEVSIIQGAVSEKTLLNFSEELHDIVKLFAKNGFDFNTDTDFDLMDNDVILASAELGSHDKKIVVSPFDSESEKIFITNGYQVFTPDNFKLEK
>NC_015167.1|WP_169309926.1|2685133_2687119_+|AAA-family-ATPase
MKKFKEDPKSSAINYEKINTFKDQSLRTVRIDQKYRAIIQAPEEGNGFHLLWVDNHDEAMDWAKNKVFEWNASTQSFQMYDRPKNQTKPVSTNVTVKDAASLYTSYSDDQLTSIGVPKDLIGLVKSIERVEHLESYASNLPSDVYEYLYYLSEGISLEDILEEIEAGKVSDDNTLSPNAQKNVYVLTDDAELENILSGDFEKWKLFLHPSQRSIAYGEFKGPLKVTGSAGTGKTVCALHRAKYLSQKLESFDKPILFTTFTKSLTQYLSTVTEKFSIPDSEIVISNIDKLIFELAREFKVIDESSGMINSSQELELWKEIIEFNPSTFDEKFLQDEYNDVILANSVKSVNEYYKTSRVGRSVRIGRQDKTQIWELCEEFIKSKESNYTKFELCNLLIAYFSSISEKPFSHIICDEIQDFSNLELSLLRVLVNEKEDDLFLVGDPFQNIYGRRINFSKSGIHIRGRRSRKLKVNYRTTEEIKKRAVSILLNTEYDDFDGEKETNTGYVSLMHGSDPTYKVFASPEAEDQYISEQIETLLLDDSVNPSDICIASRTNRLVDESKKLLNEIQQKFSDIKATIRSNDSIVVSTFHNLKGHEFKHLFVRGFSKDYVPFRHPGFDIYSDIQKKEYLKKEKSLYYVVFSRAIQTLIITGVGEKSDWIV
>NC_015167.1|WP_013621948.1|2687199_2687883_-|ATP-binding-protein
MKQSETIFNPKAPHILIEGATQFELGSFNGKAINYDFPKILNYLDAKGKLCFGKNFKIYKEDHELLLELASYFIQDHEYCKKLNIDTKKGILLSGPVGCGKTTLMRLLPHLVPHKKTYNFIPCRNIVFGFNGIGFKMIEDYSDNKAYCFDDLGVEHIGRHYGKDCNVMGEILISRYEVFKQKDILTHITTNLNAVEIEERYGERVRSRMRSMFNLLSFDSNTKDKRG
>NC_015167.1|WP_013621950.1|2688586_2688859_-|helix-turn-helix-domain-containing-protein
MPTSILTTDDLYDFKLELLRELKKLLQDKAPTAIKKYLKSAEVMEMLQISPGTLQNLRINGTLPYTKIGGIILYEYEEILRILQENKVAS
>NC_015167.1|WP_013621951.1|2689039_2689873_-|RteC-domain-containing-protein
MNVTKKQIIKIEESNLRNLSVLNDGLNLSVQTLNKLRKNLRTKDNFFTQEEEISFFKYDKPFINGRIKFFSKVRRFIAEKPNASITKQIKYVHSTIDKLEKHKMRNLEFFQYTRQCNNTLDHIYFVRGKDNLDFPVDTSHYFTDPEFSTSHDNLAAQVIGYDLLSNYYDLELEYLNKKKENVIIEEVSPAILNGLSWTASKTDLVEIIYALHSAGAIRNGQAELSKMAEVCATLFDLNLNNFYKTYAEIKNREKDTTKFLDHLKRSLEKRIDLDNAK
>NC_015167.1|WP_013621952.1|2689982_2691254_-|site-specific-integrase
MRSTHTFSILFWADQKNAINGEVLIYARITVDKKRANISLKRRVPQNLWDPKKKKLRGNSHQAQSANQYLDQIYTQLFQIYQDLKFKGELITAQLIKAQYTGEADNKGKSLKNIFEYHSKKITNTLASGSIRNFGITENYVFKFLEQKRKTTDIYLNQLNFEFLSHFELFLSEVWPTGHPKALGNNTRMKHIQRLRKVVTLAYHLEWIDKDPFVRWKMTYDKTNREFLSEQELKKLENKVFISERLDRVRDLFVFSCYTGISYVDIMNLTPNHLVLGIDGGYWIMTKRQKTNTTVKVPLLGQALDIVNKYKDHPVTAVNNSLLPVLTNEKLNMFLKEVANFVGINKNLTFHMARHTFATTVTLSNGVPIETVSKLLGHSKIATTQIYARVLENKVSADMNALKNVLLNKSKDSTVAKNSKASS
>NC_015167.1|WP_013621953.1|2691642_2692155_+|adenine-phosphoribosyltransferase
MNFKEYIRDVQDFPKQGIVFKDITPLLNNAEILEKTTDALLNLVKEQKIDKVVGMESRGFFFATLLATKLKAGFVPVRKKGKLPFNVLSKPYSLEYGEDALEIHTDAIKKGDKVLIHDDVLATGGTAKAVCELIEELGGEVVQCNFLIELDFLNGKDKIANYNVDSLLHY
>NC_015167.1|WP_013621954.1|2692151_2692304_-|hypothetical-protein
MKKALFRFLAKINRLLLPSYSKKQLDLSKASKLQLAIIGWRYYVTTNAID
>NC_015167.1|WP_013621955.1|2692879_2693815_+|calcium/sodium-antiporter
MLNLVYIIIGLVFLIMGGNWLLKSSVALSLRLQIPKIVVGMTVVSFATSAPELIVSIKAALEGSPDLALGNVVGSNIANLGLVLGVIVMLGSIDVRKSFYTTDWPILMLASLVFFGFIYFDGVIKFYEGVIMVALLIVYIVYLIKFQKTAVEDEAPEDDVPLPTFKMLLFLALGGLGLWGGSELLVSGATGLARFYNVSERVIGVTVVSVGTSIPELAASIIAVIKKEKAISLGNLIGSNIFNIFAVLGITALITPLNVVDNTLLSNDILWMLGFAIILLPLVFFPKGLRLGWRDGIVLLSGYIAFVYFTI
>NC_015167.1|WP_013621956.1|2693902_2694913_-|glutamine-synthetase-beta-grasp-domain-containing-protein
MSKSKLEYIWLDGYTPTANLRSKTKVEDDFSGKLEDCPIWSFDGSSTQQAEGGSSDCLLKPVAIYPDPARKDGYLVMTEVLNADGTPHLSNSRAGIDDEDNDFWFGFEQEYFIMDKNTQLPLGFPVGGYPGPQGMYYCSVGGKNTHGRDFVEEHADLCIAAGLNFEGINQEVASGQWEFQLFAKGAKKAGDEIWIARYLLDRLTEQYGYYIEYHPKPVKGDWNGSGMHANFSNTILRTCGSKETYEKICEAFRPVTKEHIAVYGEFNDQRLTGEHETAAITDFSYGISDRGASIRIPIITVEKGWKGWLEDRRPASNGDPYKIAGRIIKTVKSAKI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_015167_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015167_2

2678207-2678490

Unclear

Consensus_repeat	Method
GTTGGTAAATCAGGTTAGTAAATAAATA	CRISPRCasFinder

3 spacers

cas3

The CRISPR arrays of NC_015167_2

>merge|NC_015167|2|2678207-2678490|CRISPRCasFinder
GTTGGTAAATCAGGTTAGTAAATAAATAATAGATGATACCTCTATTTACGGCGACCAGAAGCATATTTACAAATATTGGTTGGTAAATCAGGTTGGTAAATAAATAGATTATAACCAAATCTTAAATTGTTGATAATAAAACAGTTAATAAACAGACTGTTTAAAAGGTTGGTGAATCAGGTGGGTAAATAAATGAATTTGAATTGCTCATAAACCGCTGTAAACACTTGTTTTACGATTAATTAGGTTTTTTAGGTGGGTAAATTGGGTGGGTGAATAATTTT

>NC_015167|2|2|2678207-2678490|CRISPRCasFinder
GTTGGTAAATCAGGTTAGTAAATAAATA	ATAGATGATACCTCTATTTACGGCGACCAGAAGCATATTTACAAATATTG
GTTGGTAAATCAGGTTGGTAAATAAATA	GATTATAACCAAATCTTAAATTGTTGATAATAAAACAGTTAATAAACAGACTGTTTAAAAG
GTTGGTGAATCAGGTGGGTAAATAAATG	AATTTGAATTGCTCATAAACCGCTGTAAACACTTGTTTTACGATTAATTAGGTTTTTTAG
GTGGGTAAATTGGGTGGGTGAATAATTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015167.1\|WP_013621938.1\|2664691_2665069_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224218
NC_015167.1\|WP_013621953.1\|2691642_2692155_+\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NC_015167.1\|WP_013621936.1\|2662411_2662738_+\|YegP-family-protein	unknown	unknown	gnl\|CDD\|377831
NC_015167.1\|WP_013621940.1\|2665497_2667927_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NC_015167.1\|WP_013621939.1\|2665079_2665517_-\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|225876
NC_015167.1\|WP_013621944.1\|2672069_2676824_+\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_013621950.1\|2688586_2688859_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_015167.1\|WP_013621954.1\|2692151_2692304_-\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_013621935.1\|2661549_2661807_+\|hypothetical-protein	unknown	unknown	unknown
NC_015167.1\|WP_013621946.1\|2678733_2685039_+\|DEAD/DEAH-box-helicase	cas3	cd09710_cas3_CAS-I-D	gnl\|CDD\|350681
NC_015167.1\|WP_169309926.1\|2685133_2687119_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223288
NC_015167.1\|WP_013621955.1\|2692879_2693815_+\|calcium/sodium-antiporter	unknown	unknown	gnl\|CDD\|223604
NC_015167.1\|WP_013621942.1\|2668934_2669207_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_015167.1\|WP_013621952.1\|2689982_2691254_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271185
NC_015167.1\|WP_013621948.1\|2687199_2687883_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|236153
NC_015167.1\|WP_013621941.1\|2667928_2668780_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|275263
NC_015167.1\|WP_013621943.1\|2669225_2672063_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|350769
NC_015167.1\|WP_013621956.1\|2693902_2694913_-\|glutamine-synthetase-beta-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|177922
NC_015167.1\|WP_013621951.1\|2689039_2689873_-\|RteC-domain-containing-protein	unknown	unknown	gnl\|CDD\|378161
NC_015167.1\|WP_013621937.1\|2663685_2664702_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015167.1\|WP_013621938.1\|2664691_2665069_-\|hypothetical-protein	gnl\|CDD\|224218	COG1299, FruA, Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism].	0.00592972
NC_015167.1\|WP_013621953.1\|2691642_2692155_+\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	7.51867e-95
NC_015167.1\|WP_013621936.1\|2662411_2662738_+\|YegP-family-protein	gnl\|CDD\|377831	pfam07411, DUF1508, Domain of unknown function (DUF1508). This family represents a series of bacterial domains of unknown function of around 50 residues in length. Members of this family are often found as tandem repeats and in some cases represent the whole protein. All member proteins are described as being hypothetical.	2.66547e-20
NC_015167.1\|WP_013621940.1\|2665497_2667927_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	9.1834e-16
NC_015167.1\|WP_013621939.1\|2665079_2665517_-\|DUF1232-domain-containing-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	0.000217355
NC_015167.1\|WP_013621956.1\|2693902_2694913_-\|glutamine-synthetase-beta-grasp-domain-containing-protein	gnl\|CDD\|177922	PLN02284, PLN02284, glutamine synthetase.	2.17817e-132
NC_015167.1\|WP_013621950.1\|2688586_2688859_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.18442e-09
NC_015167.1\|WP_013621946.1\|2678733_2685039_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|350681	cd17923, DEXHc_Hrq1-like, DEAH-box helicase domain of Hrq1 and similar proteins. Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. Hrq1 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.21426e-55
NC_015167.1\|WP_169309926.1\|2685133_2687119_+\|AAA-family-ATPase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	2.63668e-15
NC_015167.1\|WP_013621955.1\|2692879_2693815_+\|calcium/sodium-antiporter	gnl\|CDD\|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	8.97616e-61
NC_015167.1\|WP_013621942.1\|2668934_2669207_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.75739e-08
NC_015167.1\|WP_013621952.1\|2689982_2691254_-\|site-specific-integrase	gnl\|CDD\|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.82123e-57
NC_015167.1\|WP_013621948.1\|2687199_2687883_-\|ATP-binding-protein	gnl\|CDD\|236153	PRK08116, PRK08116, hypothetical protein; Validated.	3.54437e-06
NC_015167.1\|WP_013621941.1\|2667928_2668780_-\|radical-SAM-protein	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	3.44684e-25
NC_015167.1\|WP_013621943.1\|2669225_2672063_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	8.25432e-51
NC_015167.1\|WP_013621951.1\|2689039_2689873_-\|RteC-domain-containing-protein	gnl\|CDD\|378161	pfam09357, RteC, RteC protein. Human colonic Bacteroides species harbor a family of large conjugative transposons, called tetracycline resistance (Tcr) elements. Activities of these elements are enhanced by pregrowth of bacteria in medium containing tetracycline, indicating that at least some Tcr element genes are regulated by tetracycline. An insertional disruption in the rteC gene abolished self-transfer of the Tcr element to Bacteroides recipients, indicating that the gene was essential for self-transfer.	9.30356e-86

>NC_015167.1|WP_013621944.1|2672069_2676824_+|hypothetical-protein
MIEFLENIGDYFSQHFFDEDFPKKVFDKSGYGADHIKEFTSKIAPLSEKYYKFKNDYLNLRRTKDKVKRTHDFHTQLLQALGYINGVRAYDEPVVMDDKKIIPIRYRFNKNDKPYLYIMEMQPMIQVGEVDADGLYEQSYIKEDWEKVLPDSWDGYDIRPEVIKEALSELFLLPEEERPVYLIMLAGPKIFLIQYEKWKFDSYLLFDLEELFTVTKTASNKNLLALFYALLAKKQFISETESVLVGLEEDAHKASYGVTVTLKSAVIYAVEALANEAIYYKSSQAKTLEAKKEIVTLLDNDNFARELKDECLEMVYRLLFLFYAESRADLEILPIKDSTYQKGYSLEMLRDLEMVPLTTDSSRNGYFFSESLWKLFDFLHTGSDLKDGFQMRPLDSPLFDNASLKQLKGIQFRNKILQEIVVRLSLSERTKNKGRGRISYANLGINQLGSVYESLLSYSGFFAREDLIEVKNAKDKNGTDGTFLVPKTRRDDFKESEILKHEEYPEQDVIIPKGHFVYRLNGRDRKNSASYYTPEVLTQTTVKYTLKGIIERLKEKQAIVDGVLTGEACADEILKLKILEPAMGAAAFHNEVINQLAVAYLELKENEEQAAGRKRITPGIYKDELQKVKAYIAANNVYGVDLNPTAVELGKLSLWLNCMHKNMETPFFAHRLGAGNAVVGAWLKVYNDKDCLEEFPVLANGKIGKKPIPKPWWDKAPKRVMWNKKGTLSRKQNQIYHFLLPDDNMVPSYGIKLLKNELTEVEQKAFKDWRNEFKKPLTRVELNRLEKISNVIDYLLEEHYKQQMGMVKDTASVYQVYGQPNPQTTTKGYDEKERLTDSRKDRSAPYFKLKMILDYWCSLWFWDVRDVRLLPNRTEWYNEVESILQIDSNELLADGSSQDIKDQIRKKARAGTLFDTSDRIDNIEQLAQQHRFFHNEIEFVEVFYERGGFDVIVGNPPWVSITMDEAGILSEKNPEIFIKKMSASQVKKLAPKILENDVKLNEDFKKEFIWAQSTKQFLGAIQNYPLLQGHRNNLYKSILTNTFDLSSENGSIGLIHPDGIYDNPKGQKLRKTLYKRLDYHFQFQNKLMLFSEIKDKIIYSINIYSSPSEINFKNINNLFSVSTIVNSFGHSGLGICGGLKEKNVLNNQFEWNTSPHKSRIVQIESKSLKILQELFEPGANYESAKLPSIHSEDILKILEKLKENGGTLSDIKFFSTDCWNEVNSQNQGVIEKKVHYPTLDNFEFIYSGPHFFTANPFYRNPQIMVNNHNDYDIINLNLIDQNFIPRTIFTRYEDSDLFKNRVVGLDNWIFTYRLAMGKMIDTMSERTLQSTIIAPYTSHTNSVISIQTKSEFELLQLSGLSFSLVMDFYIKSLGKSNIYDNTIRNLIFGLDDIFLIFLNSRTLLLNCLSSAYQSLWERNWNEDFKKDSWSKKDTRLKPFNDLTKEWKWETPLRNWFERRQALVEIDVITAMALGLSLEELILMYNVQFPVLQQNEDDTWYDATGNIVFTVSKGLVGVGLDRSGWNSIKDMKAGETYEHTITKSELYQGKTITYHAPFTKCDRVEDYKTAWAHFENIFKTEEAVV
>NC_015167.1|WP_013621943.1|2669225_2672063_+|DEAD/DEAH-box-helicase
MNNDTLTQQTKKVTPGIRISLRGEDFIVTNRERDIIDVEGISELVYGQSFKFDLRLEKNYKVIKPEETELKADTSAHYRQTKLFLETTFRNSSHYSEHIEIAHKAAIRGANYQFESTIKALKLPQPKILIADAVGLGKTVQVGIFLAELIRRGKGKKVLVVTPKSILSQFQQEIWARFAIPLVRLDSQGIAKIKIEIPSNKNPFDYYDKVIVSIDTLKNNAKFRHYLERVKWDVVAIDECHTVANVASQRGGLAKFLSERTEAMVLTSATPHNGKRENFANLIGMLDPTAIPFNGEFTKEAIQPLYVRRFKKDVEDEVGDAFRDRVTSKIDCPLNRDEEEALRIIQEFKKVAQEDSDGDYNFEALLFSIGLFKAYMSSPKACLETVIKRIEKNIDEEGVIEHLTELRVILQKIVDEKSDSKYNQLKFKLDQMGWKGKKNDERIIIFAERRATLNELEKNLTEDFGLKPKAVVQFNGSLTDTQQQDILEDFSKEDSEIRLFLASDAGSQGVNLHYFCNQMFNYDIPWSIITLDQRNGRIDRFGQKQTPFIYYLISDSKSEDVQGDIRIVEKLKEKEEEVHKSLGDAGSVMGFYDQQQETKLVEKAIATGDDSLLDTKNKDVIDDDWLSSLMEDTATTKEEIKKDEGFASFYPDDFTYYATLIDELKAEDERLIPRITIDREDKVVEIEQFEELSSKGVLYDMPKEAFPQKNETFNLTTDSEIVERSIIRARKKQNEWPNFQLLYDLNPIAKWMQYKLLAQVDRGKALVARLREPLPKNTAWFVFQGITSNQQGKPMFSKTFVIGKSFDGASVGNLETFNEFLNQFRLNDRLTELETTNEQLDKIKSLLPEAVKRGEQLYKYTLQGGLEDELEEKLESYQEKLESWLTASEAQMELKFGDETSGSFHKKKRQREVNYVKEQMDEFYNEFFQLENEPFLRVLAVFFNA
>NC_015167.1|WP_013621942.1|2668934_2669207_+|helix-turn-helix-transcriptional-regulator
MIGERIRTLREANDILLRQLAAKLDMDQALLSKMERGERSFRKEDIDALAKIFKQSKKELLTLWLADKILKTVGSEKFSKEALRLAIENV
>NC_015167.1|WP_013621941.1|2667928_2668780_-|radical-SAM-protein
MDQLNLFSEEEVKREKLGKTAIEYKAASSILTPASGFMADYDYTLNPYSGCSFGCTYCYAAFFSRNKEKMDGWGDWLTVKENALSLLKKKRKRPLIDKTIYLSSVTDPYQPVEKELELTRSILKELLDFHKVRLVIQTRSALVTRDIDLLQKYETLQVNMTVTTDSEKVRKVFEPFCTGNKQRIKAITEMHNAGIQSCITMTPLLPIENPVQFADDLLATGIKRFIIQPFHKDKGKFVRGTRNEALKILNEFNWSDEEYNRVLSVMREKIPNLGIGKTGFAPI
>NC_015167.1|WP_013621940.1|2665497_2667927_-|ATP-dependent-helicase
MYNNYLDWLENQRSILDELFARAGFTFYEKHKHLDNFSFDANETQKECYLLGTDRDLCYDRFTIGLSYSLWYQGKRTNAFISYFAKLLYEAREENEITLLDLGAGTGAVQLAISLCKIGLDQLFGKSPKITIINIDTSPFMLDYNRSYLWPEFIKSYEIAKDIKTIYSVNSWEQTDTSNFNNFWITASYLFDQSDNVQHLSDNLSKLVETFEPRFIICNTSKRKSYLMNKASVPIKNQNYEVLSIDMKHLFTGSLPSTLAVRRKIKEECGVQYNGMPVWQENWMSSIILRLATPGLSIPIESPSVDLFTPPLTVRRDIILSPEQKKAAEDDGRPTVIYGPAGCGKTVVITERIINILKNSSEKPIEEISILVTTFNKGLVSVIKSWLKELLSREKFKFIDRGDSLRVGESTKDTITIMHFDVLPTRLWSKISDAPTPFKNDKIQFDNYHLSVAARAINTIKKKYGITTNVYDHVLNDRYVIDEYHYVIYGQDIAEASIYAKARIKGRKRLERDGNSRKYLFESVVLYLELLGLNSSFVKRRHQFYKELKKSNKGFGFSHLIVDEFQDCTQTDYNIFYELLKNPNNLIICGDFAQAIHLGNVANIPRLSQEDMGRRKFIQLVGSYRLPYRISECLQNFSKNIVTEEDDIKNPLSPFKGAPPGARPILIKASNSKEMALKIKNAVSSYHQYDIFNFNVVPYDNILILEKDAELRNELALFRRGLSYDETILKVKGLEKKCVVWTARKNIEFSERIRHYVYTILTRTSGILIIALFGEECKEYKDIINEFDPERVIIWDQDTKNYLDENYKL
>NC_015167.1|WP_013621939.1|2665079_2665517_-|DUF1232-domain-containing-protein
MKTTSFKKFKFEDLLLNNTRDYQNKHSELIRSAPYIYQLLTSLLDVTDLSVANRSKIFTSIGYFLVPKDLYSEDEHGAIGYIDDILLAIFVIKEVETEIGFEQIERLYNQDLNNLDELLNSGIYDNAIKDYDELFQEVLEFVGFY
>NC_015167.1|WP_013621938.1|2664691_2665069_-|hypothetical-protein
MEDKKSEQNILEKAINYISKLSSSKKEKLMTILKKVNEVQSSNLTTKEKAKEIKRIMWSDQSTNSKLFIGAFLGAVTGFFIFGTGGIGIAALGTGVGVWGWLATAAGGAFISSLIHNYEKKENEN
>NC_015167.1|WP_013621937.1|2663685_2664702_-|hypothetical-protein
MKINSINEITQAIKNFDIAALKELLDDNKPYQDVPKSLFLEKLEKKFNQARRDDCHSFDDVFFGICESCNKGCEGMTFLSNSGYYLDLFIESKDEEFADDIYVCNKLTNFTDLEKSIDLGFSFRKDEYYNFKPTSKYLIIKKEYNELLNQISEIEKPIKVDKLLNWYYNNFNYLSETINGFGPFECFDYNLYNDAYSLVSKVERVFEITQVKEQAIESLVDYHNSSTERERLIWFFKNQENLYGSIYFEFSEKWKTDSIIFYEQEQVELELDITGYEYVIDYFLILDNLYDELIEKYKPIPVHFEGSKNGSIECSLENYLRLRNKYIDVVKKYGRKGY
>NC_015167.1|WP_013621936.1|2662411_2662738_+|YegP-family-protein
MSKFEVYQDARSEYRFRLKADNGQKILASEGYSAKAGCMNGIESVRKNSQDDKRYERLKASNGKHYFNLKASNGQVIGTSEMYESSSGMENGIASVTSNAPKATIEEV
>NC_015167.1|WP_013621935.1|2661549_2661807_+|hypothetical-protein
MNIVERYKKPTPKFFRTLRNIGIALATAGGAIIAAPISLPAVLVTVATYMTVAGTVATAVSQAVTIDEKTEIPKIDGKDSASNIK
>NC_015167.1|WP_013621946.1|2678733_2685039_+|DEAD/DEAH-box-helicase
MLPLLQANEIKQAVVDYLRSTFNFEDPLLDQSFEDFLLSEQKGMFKGPYMQLRLPFDKIATDGDRDAFAKALYVKPPFDPYHHQFLSFLKLSTRNGHKPEPVILTTGTGSGKTESFLFPLLDYCYQHRDKPGIKAIILYPMNALATDQARRIAEEINDFNDGELKGKIRAGLFIGEGKDKDGIRATRMSEDRIIEDRKTLVDAPPDILLTNFKMLDFALLQARFHNLWSHNFKNTDLLKFIVLDELHTYDGAKGSDVANLIRRLKLKLKLPKDQIVPVGTSATMGGGDQGKLELVDFFSKVFGVKVTTDAVIEEQRLEPDEFFDDTIEEPVIDVNQIQKCAFEENDTYLSYLERQLVFWGYAGLSPKDLGDALKKNKWFFDLLKITKSDVVVIKPKLKRWREKIGLELDDKEIHLLFSSLLALITYAKEQSGSKQFPFLYLQITYWLRSLSKIVRKLQPTAAFEWESDMNPNDPVKSLPPYFCRECGGSGWIGIKKEQNAHFEDDLSRTRQQLMAHSQNKNLYFISSLEDRKYQEVYASDYTHSGDAIDGYLHPHSLSIYDNYESNDYFKILGTRIVDGNRIDKICPHCNSRNTLALIGTGVPTLESIATAQVLATATDPTKDGQRKLLAFTNGVQDAAHQAGFIENRNFRFGMRHAIQAVLKDVKEPITLPQVYERFIEHWKEHSDDEETGNLDAYYYKFFPPDCDARLEISDYRNKDGKLSSVFDKEFSNRMSWEIWSEFSYSAMIGRTLEKTGASATYFDTAVMSEVYDQMKYWLDENKLGTAIDKEPFLKFLNGFLHRLRTKGGVDHKYLKKYRTERTNSYLIGHRGNVNKQYFLMKNFGPSSRLPKFLALANGANTRAFDVVQTTTKDNWFSAYFKKCFQEIIQEETVLINDFYAQLLDYLDANKILDKRVAAGVTNYGLSENSIYLSPNVVHYECSHCGNQINTGAAQASLVSGMKCLQYRCKGQYEAAENSQLDYYRMVYNRGRSLRIFAKDHTGLIDRNEREKLEYDFKRQPKQDSTNVLVATSTLEMGIDIGDLNVTFNSSLPPETANYLQRIGRAGRSSGTSMILNLAGRDAHDLYYFQDPQDMMSGQIKTPSCYLEAKDILKRHFMAFCFDHWASMDPEENNIPPMVRVLRLKSLKPGDPNFLFQKIATHIENNKTLLYDLFVEQYKEQLGDNSKSLASIFEDLSSGRFINRLTCLHKNLLDEIEYYQEKIKLVNKRLKALPETGNETVILKNEKRALSSAIYNINRRNVIEYLTNVGVLPNYAFPETGVTLNAQIKRKKEVDGKTEYKYEDFSEIVRPSSSALTELAPANIFYSQGHKLKSEGLEIKSQEDYEEHRFCSNCNHVKKEIDVEENEQSQCPVCGHGSWSSLNNRKFLVKLQGVLSVNDKERSKITDSSDDRERHFYQKSVHIKINQSSSQGAHVLKRVPFGIEFFQDVDYLEINTGIREEGFFGTREIEINGEKHPQVGFVVCKTCGKSTERSLSARELNNRDRAYHFPYCSNREVLYADQSDDVFNEIYLYRKFNTEALSILLPVEDFRSEERIALFKAGLKLGLKEYFKGRPDHILIRENEIFNKTTNRKDRYLVFYETIPGGTGYLSKLFDTTVFTKILEKAYERIAFCSCKQEGKDGCYRCIYTYGNQYERTILSRTEAEELFSNILEKTDEWNSIESLQNVSTFGNNEESDLEWKFKGLLEEFANKFSGSTFESDNEMGLKIYKLKLAYYGNEIVYKVYPQNLNRWLFGIEKKTRPDFVLKCVGLTKNGKKFTLDELETIKDIVIYLDGYEYHASENHSDRFPKDLEIRNSIINSGRYNQWVFTWSDFAESIFNDKDAIGLKQDEKFIVGKFFLKHSSFKEYDFRDVYYNNNATRFFQLLINPITVVDNKNWSSLAVFSFQSKMMGVSYSPENVEQIIETRSIKDIEKGTLKLTNYIHADDLQLKDEASFGLFIRPEDFKLKGYGYYKAVPFWDKENWALFWRFYNLTQFHNIEVYSFDKEIKKEVSIIQGAVSEKTLLNFSEELHDIVKLFAKNGFDFNTDTDFDLMDNDVILASAELGSHDKKIVVSPFDSESEKIFITNGYQVFTPDNFKLEK
>NC_015167.1|WP_169309926.1|2685133_2687119_+|AAA-family-ATPase
MKKFKEDPKSSAINYEKINTFKDQSLRTVRIDQKYRAIIQAPEEGNGFHLLWVDNHDEAMDWAKNKVFEWNASTQSFQMYDRPKNQTKPVSTNVTVKDAASLYTSYSDDQLTSIGVPKDLIGLVKSIERVEHLESYASNLPSDVYEYLYYLSEGISLEDILEEIEAGKVSDDNTLSPNAQKNVYVLTDDAELENILSGDFEKWKLFLHPSQRSIAYGEFKGPLKVTGSAGTGKTVCALHRAKYLSQKLESFDKPILFTTFTKSLTQYLSTVTEKFSIPDSEIVISNIDKLIFELAREFKVIDESSGMINSSQELELWKEIIEFNPSTFDEKFLQDEYNDVILANSVKSVNEYYKTSRVGRSVRIGRQDKTQIWELCEEFIKSKESNYTKFELCNLLIAYFSSISEKPFSHIICDEIQDFSNLELSLLRVLVNEKEDDLFLVGDPFQNIYGRRINFSKSGIHIRGRRSRKLKVNYRTTEEIKKRAVSILLNTEYDDFDGEKETNTGYVSLMHGSDPTYKVFASPEAEDQYISEQIETLLLDDSVNPSDICIASRTNRLVDESKKLLNEIQQKFSDIKATIRSNDSIVVSTFHNLKGHEFKHLFVRGFSKDYVPFRHPGFDIYSDIQKKEYLKKEKSLYYVVFSRAIQTLIITGVGEKSDWIV
>NC_015167.1|WP_013621948.1|2687199_2687883_-|ATP-binding-protein
MKQSETIFNPKAPHILIEGATQFELGSFNGKAINYDFPKILNYLDAKGKLCFGKNFKIYKEDHELLLELASYFIQDHEYCKKLNIDTKKGILLSGPVGCGKTTLMRLLPHLVPHKKTYNFIPCRNIVFGFNGIGFKMIEDYSDNKAYCFDDLGVEHIGRHYGKDCNVMGEILISRYEVFKQKDILTHITTNLNAVEIEERYGERVRSRMRSMFNLLSFDSNTKDKRG
>NC_015167.1|WP_013621950.1|2688586_2688859_-|helix-turn-helix-domain-containing-protein
MPTSILTTDDLYDFKLELLRELKKLLQDKAPTAIKKYLKSAEVMEMLQISPGTLQNLRINGTLPYTKIGGIILYEYEEILRILQENKVAS
>NC_015167.1|WP_013621951.1|2689039_2689873_-|RteC-domain-containing-protein
MNVTKKQIIKIEESNLRNLSVLNDGLNLSVQTLNKLRKNLRTKDNFFTQEEEISFFKYDKPFINGRIKFFSKVRRFIAEKPNASITKQIKYVHSTIDKLEKHKMRNLEFFQYTRQCNNTLDHIYFVRGKDNLDFPVDTSHYFTDPEFSTSHDNLAAQVIGYDLLSNYYDLELEYLNKKKENVIIEEVSPAILNGLSWTASKTDLVEIIYALHSAGAIRNGQAELSKMAEVCATLFDLNLNNFYKTYAEIKNREKDTTKFLDHLKRSLEKRIDLDNAK
>NC_015167.1|WP_013621952.1|2689982_2691254_-|site-specific-integrase
MRSTHTFSILFWADQKNAINGEVLIYARITVDKKRANISLKRRVPQNLWDPKKKKLRGNSHQAQSANQYLDQIYTQLFQIYQDLKFKGELITAQLIKAQYTGEADNKGKSLKNIFEYHSKKITNTLASGSIRNFGITENYVFKFLEQKRKTTDIYLNQLNFEFLSHFELFLSEVWPTGHPKALGNNTRMKHIQRLRKVVTLAYHLEWIDKDPFVRWKMTYDKTNREFLSEQELKKLENKVFISERLDRVRDLFVFSCYTGISYVDIMNLTPNHLVLGIDGGYWIMTKRQKTNTTVKVPLLGQALDIVNKYKDHPVTAVNNSLLPVLTNEKLNMFLKEVANFVGINKNLTFHMARHTFATTVTLSNGVPIETVSKLLGHSKIATTQIYARVLENKVSADMNALKNVLLNKSKDSTVAKNSKASS
>NC_015167.1|WP_013621953.1|2691642_2692155_+|adenine-phosphoribosyltransferase
MNFKEYIRDVQDFPKQGIVFKDITPLLNNAEILEKTTDALLNLVKEQKIDKVVGMESRGFFFATLLATKLKAGFVPVRKKGKLPFNVLSKPYSLEYGEDALEIHTDAIKKGDKVLIHDDVLATGGTAKAVCELIEELGGEVVQCNFLIELDFLNGKDKIANYNVDSLLHY
>NC_015167.1|WP_013621954.1|2692151_2692304_-|hypothetical-protein
MKKALFRFLAKINRLLLPSYSKKQLDLSKASKLQLAIIGWRYYVTTNAID
>NC_015167.1|WP_013621955.1|2692879_2693815_+|calcium/sodium-antiporter
MLNLVYIIIGLVFLIMGGNWLLKSSVALSLRLQIPKIVVGMTVVSFATSAPELIVSIKAALEGSPDLALGNVVGSNIANLGLVLGVIVMLGSIDVRKSFYTTDWPILMLASLVFFGFIYFDGVIKFYEGVIMVALLIVYIVYLIKFQKTAVEDEAPEDDVPLPTFKMLLFLALGGLGLWGGSELLVSGATGLARFYNVSERVIGVTVVSVGTSIPELAASIIAVIKKEKAISLGNLIGSNIFNIFAVLGITALITPLNVVDNTLLSNDILWMLGFAIILLPLVFFPKGLRLGWRDGIVLLSGYIAFVYFTI
>NC_015167.1|WP_013621956.1|2693902_2694913_-|glutamine-synthetase-beta-grasp-domain-containing-protein
MSKSKLEYIWLDGYTPTANLRSKTKVEDDFSGKLEDCPIWSFDGSSTQQAEGGSSDCLLKPVAIYPDPARKDGYLVMTEVLNADGTPHLSNSRAGIDDEDNDFWFGFEQEYFIMDKNTQLPLGFPVGGYPGPQGMYYCSVGGKNTHGRDFVEEHADLCIAAGLNFEGINQEVASGQWEFQLFAKGAKKAGDEIWIARYLLDRLTEQYGYYIEYHPKPVKGDWNGSGMHANFSNTILRTCGSKETYEKICEAFRPVTKEHIAVYGEFNDQRLTGEHETAAITDFSYGISDRGASIRIPIITVEKGWKGWLEDRRPASNGDPYKIAGRIIKTVKSAKI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015167_1	1.5\|187180\|30\|NC_015167\|CRISPRCasFinder	187180-187209	30	NZ_CP014680	Kozakia baliensis strain DSM 14400 plasmid pKB14400_6	1794-1823	8	0.733
NC_015167_1	1.2\|187006\|33\|NC_015167\|CRISPRCasFinder	187006-187038	33	NZ_CP012100	Bacillus thuringiensis strain HS18-1 plasmid pHS18-1, complete sequence	10309-10341	9	0.727
NC_015167_1	1.2\|187006\|33\|NC_015167\|CRISPRCasFinder	187006-187038	33	MF417897	Uncultured Caudovirales phage clone 9F_6, partial genome	2201-2233	11	0.667

1. spacer 1.5|187180|30|NC_015167|CRISPRCasFinder matches to NZ_CP014680 (Kozakia baliensis strain DSM 14400 plasmid pKB14400_6) position: , mismatch: 8, identity: 0.733

ggtaactgcaaaagaaactatagacgctag	CRISPR spacer
atttattgcaaaagaaactatagaggcatc	Protospacer
. * *.****************** **

2. spacer 1.2|187006|33|NC_015167|CRISPRCasFinder matches to NZ_CP012100 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-1, complete sequence) position: , mismatch: 9, identity: 0.727

cctaaaagttaaaacaaaagaactaaaagctag	CRISPR spacer
tattaaagttaaaagaaaaaaactaaaagactt	Protospacer
. * ********** ****.********* .

3. spacer 1.2|187006|33|NC_015167|CRISPRCasFinder matches to MF417897 (Uncultured Caudovirales phage clone 9F_6, partial genome) position: , mismatch: 11, identity: 0.667

cctaaaagttaaaacaaaagaactaaaagctag	CRISPR spacer
aagtaaggttaaaacaaaagaagtaaaaagccc	Protospacer
    **.*************** *****. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1540316 : 1547370

Escherichia_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013620923.1\|1540316_1541360_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.4e-86	51.4
WP_013620924.1\|1541370_1542234_+	glucose-1-phosphate thymidylyltransferase RfbA	H9NC64	Sphingomonas_phage	2.2e-99	63.1
WP_042256752.1\|1542236_1542782_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D7XFA9	Escherichia_phage	5.1e-33	45.2
WP_013620926.1\|1542778_1543558_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.7e-37	36.9
WP_013620927.1\|1543586_1544987_+	UDP-glucose 6-dehydrogenase	A0A127AXI2	Bacillus_phage	7.7e-65	34.0
WP_013620928.1\|1545031_1546156_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	2.4e-29	29.9
WP_013620929.1\|1546158_1547370_+	UDP-N-acetyl-D-mannosamine dehydrogenase	A0A127AXI2	Bacillus_phage	1.6e-26	26.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015167

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection