| NC_015177.1|WP_013632835.1|2080070_2081264_+|N-acetylglucosamine-6-phosphate-deacetylase |
gnl|CDD|238434 |
cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.
|
7.51091e-154 |
| NC_015177.1|WP_013632841.1|2090728_2091499_-|rhamnogalacturonan-acetylesterase |
gnl|CDD|238859 |
cd01821, Rhamnogalacturan_acetylesterase_like, Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are highly branched regions in pectic polysaccharides, consisting of repeating -(1,2)-L-Rha-(1,4)-D-GalUA disaccharide units, with many rhamnose residues substituted by neutral oligosaccharides such as arabinans, galactans and arabinogalactans. Extracellular enzymes participating in the degradation of plant cell wall polymers, such as Rhamnogalacturonan acetylesterase, would typically be found in saprophytic and plant pathogenic fungi and bacteria.
|
1.4693e-84 |
| NC_015177.1|WP_013632830.1|2072964_2075508_-|ATP-dependent-Clp-protease-ATP-binding-subunit |
gnl|CDD|223616 |
COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].
|
0 |
| NC_015177.1|WP_041537372.1|2092540_2095789_+|SusC/RagA-family-TonB-linked-outer-membrane-protein |
gnl|CDD|274948 |
TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].
|
0 |
| NC_015177.1|WP_013632834.1|2078750_2080064_+|sugar-MFS-transporter |
gnl|CDD|340952 |
cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
|
5.85496e-120 |
| NC_015177.1|WP_013632844.1|2095801_2097559_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein |
gnl|CDD|185760 |
cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.
|
2.45795e-28 |
| NC_015177.1|WP_013632829.1|2071613_2072831_+|porin |
gnl|CDD|369347 |
pfam07396, Porin_O_P, Phosphate-selective porin O and P. This family represents a conserved region approximately 400 residues long within the bacterial phosphate-selective porins O and P. These are anion-specific porins, the binding site of which has a higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates, while porin P has a higher affinity for orthophosphate. In P. aeruginosa, porin O was found to be expressed only under phosphate-starvation conditions during the stationary growth phase.
|
2.33332e-20 |
| NC_015177.1|WP_083811747.1|2088934_2089411_-|DDE-type-integrase/transposase/recombinase |
gnl|CDD|222853 |
PHA02517, PHA02517, putative transposase OrfB; Reviewed.
|
1.79673e-29 |
| NC_015177.1|WP_013632836.1|2081500_2082703_-|Gfo/Idh/MocA-family-oxidoreductase |
gnl|CDD|223745 |
COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].
|
1.51345e-52 |
| NC_015177.1|WP_013632840.1|2087259_2088447_+|hypothetical-protein |
gnl|CDD|373362 |
pfam14885, GHL15, Hypothetical glycosyl hydrolase family 15. GHL15 is a family of hypothetical glycoside hydrolases.
|
3.36853e-11 |
| NC_015177.1|WP_013632838.1|2085015_2086458_+|Gfo/Idh/MocA-family-oxidoreductase |
gnl|CDD|223745 |
COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].
|
6.56434e-25 |
| NC_015177.1|WP_013631395.1|2089790_2090147_-|transposase |
gnl|CDD|225511 |
COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].
|
0.000171777 |
| NC_015177.1|WP_013632832.1|2075698_2077378_+|energy-dependent-translational-throttle-protein-EttA |
gnl|CDD|236992 |
PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.
|
0 |
| NC_015177.1|WP_013632839.1|2086486_2087242_+|glucosamine-6-phosphate-deaminase |
gnl|CDD|179028 |
PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.
|
7.17102e-103 |
| NC_015177.1|WP_013632837.1|2083633_2084650_+|LacI-family-DNA-binding-transcriptional-regulator |
gnl|CDD|224525 |
COG1609, PurR, Transcriptional regulators [Transcription].
|
2.17644e-112 |
| NC_015177.1|WP_013632827.1|2069547_2070498_-|TIGR01212-family-radical-SAM-protein |
gnl|CDD|224163 |
COG1242, COG1242, Predicted Fe-S oxidoreductase [General function prediction only].
|
1.3059e-107 |
| NC_015177.1|WP_013632833.1|2077592_2078576_+|aldo/keto-reductase |
gnl|CDD|381312 |
cd19086, AKR_AKR11C1, AKR11C family of aldo-keto reductase (AKR). Bacillus subtilis uncharacterized oxidoreductase YqkF is a founding member of aldo-keto reductase family 11 member C1 (AKR11C1). It may function as oxidoreductase. This family also includes Bacillus halodurans AKR11C1, an NADPH-dependent 4-hydroxy-2,3-trans-nonenal reductase.
|
1.71831e-104 |
| NC_015177.1|WP_148233521.1|2091495_2092251_-|rhamnogalacturonan-acetylesterase |
gnl|CDD|238859 |
cd01821, Rhamnogalacturan_acetylesterase_like, Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are highly branched regions in pectic polysaccharides, consisting of repeating -(1,2)-L-Rha-(1,4)-D-GalUA disaccharide units, with many rhamnose residues substituted by neutral oligosaccharides such as arabinans, galactans and arabinogalactans. Extracellular enzymes participating in the degradation of plant cell wall polymers, such as Rhamnogalacturonan acetylesterase, would typically be found in saprophytic and plant pathogenic fungi and bacteria.
|
1.55982e-91 |
| NC_015177.1|WP_013632828.1|2070562_2071516_+|magnesium/cobalt-transporter-CorA |
gnl|CDD|213370 |
cd12836, HpCorA-like, Mg2+ transporter Helicobacter pylori CorA-like subgroup. A bacterial subgroup of the Escherichia coli CorA-Salmonella typhimurium ZntB_like (EcCorA_ZntB-like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subgroup includes the Mg2+ transporter Helicobacter pylori CorAs (which can also transport Co2+, and Ni2+); CorA plays an important role in the viability of this pathogen. Structures of the intracellular domain of Vibrio parahaemolyticus and Salmonella typhimurium ZntB (members of the EcCorA_ZntB-like family) form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA, and Mrs2p. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.
|
4.99233e-155 |
