CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017244	Brucella melitensis M28 chromosome 1, complete sequence	1 crisprs	csa3,WYL,DEDDh	0	1	2	0
NC_017245	Brucella melitensis M28 chromosome 2, complete sequence	0 crisprs	csa3,cas3,DEDDh	0	0	0	0

1. NC_017244

CRISPR-Cas detection and classification

Crispr_ID: NC_017244_1

• CRISPR_ID: NC_017244_1
• CRISPR_location: 659621-659703
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017244_1

Consensus_repeat	Method
ATCCCGAAAAGTGCGAAGCGGTTTTCGG	CRISPRCasFinder

spacers of NC_017244_1

>1.1|659649|27|NC_017244|CRISPRCasFinder
ATAAGATGCGCGCAAGGAAAGATCTGT

CRISPR arrays and Neighbor proteins around NC_017244_1

CRISPR arrays

The CRISPR arrays of NC_017244_1

>merge|NC_017244|1|659621-659703|CRISPRCasFinder
ATCCCGAAAAGTGCGAAGCGGTTTTCGGATAAGATGCGCGCAAGGAAAGATCTGTATCCCGAAAAGTGCGAAGCGGTGTTCGG

>NC_017244|1|1|659621-659703|CRISPRCasFinder
ATCCCGAAAAGTGCGAAGCGGTTTTCGG	ATAAGATGCGCGCAAGGAAAGATCTGT
ATCCCGAAAAGTGCGAAGCGGTGTTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017244.1|WP_004686526.1|658159_659041_+|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl|CDD|235107
NC_017244.1|WP_004683395.1|667712_668924_-|MFS-transporter	unknown	unknown	gnl|CDD|341031
NC_017244.1|WP_005969508.1|654907_655564_+|endonuclease	unknown	unknown	gnl|CDD|237082
NC_017244.1|WP_002963786.1|653949_654591_+|hypothetical-protein	unknown	unknown	unknown
NC_017244.1|WP_006136158.1|652717_653806_+|porin	unknown	unknown	gnl|CDD|308243
NC_017244.1|WP_004685524.1|655626_657684_-|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl|CDD|381604
NC_017244.1|WP_002970988.1|650774_651878_-|porin	unknown	unknown	gnl|CDD|308243
NC_017244.1|WP_002963792.1|659744_660416_-|uracil-DNA-glycosylase	unknown	unknown	gnl|CDD|381681
NC_017244.1|WP_002963791.1|659131_659608_+|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|235455
NC_017244.1|WP_004685525.1|662060_664313_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl|CDD|223394
NC_017244.1|WP_004683386.1|660446_661022_-|NYN-domain-containing-protein	unknown	unknown	gnl|CDD|350235
NC_017244.1|WP_002971501.1|669175_670015_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|380379
NC_017244.1|WP_002963787.1|654646_654829_+|hypothetical-protein	unknown	unknown	unknown
NC_017244.1|WP_004683363.1|649572_650499_-|site-specific-integrase	unknown	unknown	gnl|CDD|271177
NC_017244.1|WP_002963797.1|664320_664899_+|orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|273579
NC_017244.1|WP_014489380.1|665058_665814_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|236494
NC_017244.1|WP_002966733.1|670064_670640_+|DUF2062-domain-containing-protein	unknown	unknown	gnl|CDD|225757
NC_017244.1|WP_004686524.1|666194_667529_+|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl|CDD|237356
NC_017244.1|WP_002963795.1|661418_661820_+|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl|CDD|234744
NC_017244.1|WP_004686530.1|648076_649210_-|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|181255

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017244.1|WP_004686526.1|658159_659041_+|4-hydroxy-tetrahydrodipicolinate-synthase	gnl|CDD|235107	PRK03170, PRK03170, dihydrodipicolinate synthase; Provisional.	7.73311e-177
NC_017244.1|WP_004683395.1|667712_668924_-|MFS-transporter	gnl|CDD|341031	cd17478, MFS_FsR, Fosmidomycin resistance protein of the Major Facilitator Superfamily of transporters. Fosmidomycin resistance protein (FsR) confers resistance against fosmidomycin. It shows sequence similarity with the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. This FsR family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.97193e-108
NC_017244.1|WP_005969508.1|654907_655564_+|endonuclease	gnl|CDD|237082	PRK12373, PRK12373, NADH-quinone oxidoreductase subunit E.	1.44499e-28
NC_017244.1|WP_006136158.1|652717_653806_+|porin	gnl|CDD|308243	pfam02530, Porin_2, Porin subfamily. This family consists of porins from the alpha subdivision of Proteobacteria the members of this family are related to pfam00267. The porins form large aqueous channels in the cell membrane allowing the selective entry of hydrophilic compounds this so called 'molecular sieve' is found in the cell walls of gram negative bacteria.	2.63888e-115
NC_017244.1|WP_004685524.1|655626_657684_-|lytic-transglycosylase-domain-containing-protein	gnl|CDD|381604	cd13401, Slt70-like, 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.	2.23686e-60
NC_017244.1|WP_002970988.1|650774_651878_-|porin	gnl|CDD|308243	pfam02530, Porin_2, Porin subfamily. This family consists of porins from the alpha subdivision of Proteobacteria the members of this family are related to pfam00267. The porins form large aqueous channels in the cell membrane allowing the selective entry of hydrophilic compounds this so called 'molecular sieve' is found in the cell walls of gram negative bacteria.	7.06318e-105
NC_017244.1|WP_002963792.1|659744_660416_-|uracil-DNA-glycosylase	gnl|CDD|381681	cd10031, UDG-F5_TTUDGB_like, Uracil DNA glycosylase family 5, includes Thermotoga maritima TTUDGB and similar proteins. Uracil DNA glycosylase family 5 includes Thermus thermophilus HB8 TTUDGB (also called UDGb) which is not only a UDG acting on double-stranded uracil-containing DNA, but also a hypoxanthine DNA glycosylase acting on double-stranded hypoxanthine-containing DNA (except for the C/I base pair), as well as a xanthine DNA glycosylase acting on both, double-stranded and single-stranded xanthine-containing DNA. TTUDGB also excises thymine from G:T mismatched DNA, and removes analogs of uracil from DNA, including 5-hydroxymethyluracil (hmU) and 5-fluorouracil (fU). This subfamily also contains Bradyrhizobium diazoefficiens family 5 homolog Blr5068 (UdgB) which has been found to efficiently excise uracil from ssDNA and dsDNA. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Similar to family 4 UDGs, members of this family possess four conserved cysteine residues required to coordinate the [4Fe-4S] iron-sulfur cluster. Uracil in DNA can arise as a result of mis-incorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations. Thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other.	7.75632e-104
NC_017244.1|WP_002963791.1|659131_659608_+|SsrA-binding-protein-SmpB	gnl|CDD|235455	PRK05422, smpB, SsrA-binding protein SmpB.	1.57135e-88
NC_017244.1|WP_004685525.1|662060_664313_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl|CDD|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NC_017244.1|WP_004683386.1|660446_661022_-|NYN-domain-containing-protein	gnl|CDD|350235	cd10911, PIN_LabA, PIN domain of Synechococcus elongatus LabA (low-amplitude and bright) and related proteins. This subfamily contains Synechococcus elongatus PCC 7942 LabA which participates in cyanobacterial circadian timing, it is required for negative feedback regulation of the autokinase/autophosphatase KaiC, a central component of the circadian clock system, and appears to be necessary for KaiC-dependent repression of gene expression. This subfamily belongs to the LabA-like domain family which includes the N-terminal domain of limkain b1, a human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes. Also included in the LabA-like domain family are human ZNF451, uncharacterized Bacillus subtilis YqxD, uncharacterized Escherichia coli YaiI, and the N-terminal domain of a well-conserved group of mainly bacterial proteins with no defined function, which contain a C-terminal LabA_like_C domain. Curiously Pseudomonas putida S16 NicB , which is described as a putative NADH-dependent hydroxylase involved in the microbial degradation of nicotine also falls into the LabA-like family. The PIN (PilT N terminus) domain belongs to a large nuclease superfamily. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.30427e-60
NC_017244.1|WP_002971501.1|669175_670015_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	5.72308e-33
NC_017244.1|WP_004683363.1|649572_650499_-|site-specific-integrase	gnl|CDD|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.39039e-42
NC_017244.1|WP_002963797.1|664320_664899_+|orotate-phosphoribosyltransferase	gnl|CDD|273579	TIGR01367, Orotate_phosphoribosyltransferase, orotate phosphoribosyltransferase, Thermus family. This model represents a distinct clade of orotate phosphoribosyltransferases. Members include the experimentally determined example from Thermus aquaticus and additional examples from Caulobacter crescentus, Helicobacter pylori, Mesorhizobium loti, and related species. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis].	2.00708e-76
NC_017244.1|WP_014489380.1|665058_665814_+|helix-turn-helix-domain-containing-protein	gnl|CDD|236494	PRK09391, fixK, transcriptional regulator FixK; Provisional.	3.86936e-50
NC_017244.1|WP_002966733.1|670064_670640_+|DUF2062-domain-containing-protein	gnl|CDD|225757	COG3216, COG3216, Uncharacterized protein conserved in bacteria [Function unknown].	5.43979e-83
NC_017244.1|WP_004686524.1|666194_667529_+|oxygen-independent-coproporphyrinogen-III-oxidase	gnl|CDD|237356	PRK13347, PRK13347, coproporphyrinogen III oxidase; Provisional.	0
NC_017244.1|WP_002963795.1|661418_661820_+|DNA-directed-RNA-polymerase-subunit-omega	gnl|CDD|234744	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed.	1.70484e-25
NC_017244.1|WP_004686530.1|648076_649210_-|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|181255	PRK08153, PRK08153, pyridoxal phosphate-dependent aminotransferase.	0

Protein sequences

>NC_017244.1|WP_002963791.1|659131_659608_+|SsrA-binding-protein-SmpB
MNKPKNSPARKMIAENRKARFNFEILDTLEAGLVLTGTEVKSLRANQANIAESYASFEDGEFWLINSYIPEYTQGNRFNHEPRRLRKLLVSRREMSRLFNSVSREGMTVVPLKLYFNDRGRAKLELALARGKKTHDKRETEKKRDWNREKARLLRDRG
>NC_017244.1|WP_004686526.1|658159_659041_+|4-hydroxy-tetrahydrodipicolinate-synthase
MLKGSITALVTPFDREGAFDEKAFRAFVNWQIEEGTKGLVPVGTTGETPTLSHDEHKRVIEVCIEVAAGRVPVIAGAGSNNTVEAIELAQHAEKAGADAVLVVTPYYNKPNQRGLYEHFSRVARSISIPLVIYNVPGRSIIDMTPETMGALVRDCKNIVGVKDATGKIERVSEQRAICGKEFIQLSGEDATALGFNAHGGVGCISVTSNIAPRLCAEFQEACQAGNFAKALELQDRLMPLHKALFLEPNPSGPKYALSRLGRIENVLRSPMVTIEAATAEKIDHAMKHAVLIN
>NC_017244.1|WP_004685524.1|655626_657684_-|lytic-transglycosylase-domain-containing-protein
MVSLAQSSLPPEIPTPLARPFAPTATHQSPISLVTPRPRPIAPDPMATSAVSRTDNPAVIGGTLKNGLDALSAKNVASAIASRNNLPRGSLDRQILTWAIATSGMDGVPSTEIAAAASELSGWPGMATLRRNSERALFKENPSSATIIATFGSTRPQTTEGMIALARAYVATGNSTKAHQLLSPWWTRKRLSSDDEQKILKEFSAILTREDHQRRLLHSLYNGHLQSARLLAGPAQAQSLYNAYAAVAQKSPNAASAIAAVDRSWQANPVYQFLKIRYLRRAERYNEAAELLLKAPRKASVLVDPDAWWVERRILSRELLDLGKPQLAYRLAAAHAAETPTMAAEAEFHAGWYALRALNQPKLAAPHFAKITQISARPISASRAYYWLGRAAEAGSGGDARAYYRRSAHFGTTFYGQLAAAKLNEKAPELAYPKPTEAERVRFASRPAVQAIKRLEQVGYGNKAAALYTQLSQELDSVGELALLAVMAERNDNHYMALRVGKTAAMRGLDVGALSHPLGAIPASANIKGSGKALAYAIARQESEFNVSAVSKAGARGLLQLMPATAKTVATRNGMSFSAQKLTADAAYNATLGAHFLGEQLDRFNGSYVLTFAGYNAGPRRASEWVEKYGDPRGKSVEQVVDWIERIPYSETRNYVQRVMENYEVYKTRLTGRADIKTDLVYGRR
>NC_017244.1|WP_005969508.1|654907_655564_+|endonuclease
MPLLIVQLAILIAVAFVVGCFLGRILRRRKSAGSDHERTIVAAALSTPPLAEKPEPVPPAEPVRADSDPLKRKAGLEKARIEPVEGSADSDVAAAPVLKKVPAETPDDAGRPQWREAPRRGKADELTAIEGIGKAIEAVLHELGIFHYDQIAQWTREEAIWIERRIGFPGRVEREGWIAQAAKLAEPPAKSTTKRGAKTKKAANNVRSGTRRAKKQAG
>NC_017244.1|WP_002963787.1|654646_654829_+|hypothetical-protein
MTVFPIRPFLCYDYSAKGLKCLAKYYAESLMLYLVETFWPVLVLAILIGAATGWLTAGER
>NC_017244.1|WP_002963786.1|653949_654591_+|hypothetical-protein
MKKWFWPCLTWTACLTALALWFGADRVETDIAEQTAKALEPYVWAGFYVDGRDVVLKGMAPDPDMQRAAHAALEHVWAIRDITDLTTVLQLASPYRFKIGRNAQGLVLSGFIPNNESRDQVMTAAGEVAPDIFIDDEMAVARGNQPEFMERVLFAIDLAKKLPEAEIEIVDEKLSIRGTVSDEAIYDEIEALKAAQLPYGLKLAVLDVKKSVQ
>NC_017244.1|WP_006136158.1|652717_653806_+|porin
MNIKSLLLGSAAALVAASGAQAADAIVAPESEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYSGTDRNGWDKGARFALRVSTGSETELGTLKTFTELRFNYAANNSGVDGKYGNETSSGTVMEFAYIQLGGLRVGIDESEFHTFTGYLGDVINDDVISAGSYRTGKIAYTFTGGNGFSAVIALEQGGDNDGGYTGTTNYHIDGYMPDVVGGLKYAGGWGSIAGVVAYDSVIEEWAAKVRGDVNITDQFSVWLQGAYSSAATPDQNYGQWGGDWAVWGGLKYQATQKAAFNLQAAHDDWGKTAVTANVAYELVPGFTVTPEVSYTKFGGEWKNTVAEDNAWGGIVRFQRSF
>NC_017244.1|WP_002970988.1|650774_651878_-|porin
MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYSGTDRNGWDKGARFALMFNTNSETELGTLGTYTQLRFNYTSNNSRHDGQYGDFSDDRDVADGGVSTGTDLQFAYITLGGFKVGIDESEFHTFTGYLGDVINDDVVAAGSYRTGKIAYTFTGGNGFSAVIALEQGGEDVDNDYTIDGYMPHVVGGLKYAGGWGSIAGVVAYDSVIEEWATKVRGDVNITDRFSVWLQGAYSSAATPNQNYGQWGGDWAVWGGAKFIAPEKATFNLQAAHDDWGKTAVTANVAYQLVPGFTITPEVSYTKFGGEWKDTVAEDNAWGGIVRFQRSF
>NC_017244.1|WP_004683363.1|649572_650499_-|site-specific-integrase
MIIVGETKIDTGDKYAPIIDYNLNYISGKNPKHRLVEHYSVAELTAKYINILWDDGPHKYNVRSFLGEIDEILKGARFSGFDQEMLDSIIGTLRERGNSNATINRKMAALSKLLRKAHKMGDIFNLPEFIRQKERVGRIRFLEQEEEKRLFAAIKSRCEDSYRLSVFLVDTGCRLGEAIGLTWNDIQEQRVTFWVTKSNRSRTVPLTRRARKASHIPRERLKGPFSMLNQVRFRQIWNEAKAEVGLGADDQIVPHILRHTCASRLVRGGIDIRRVQMWLGHQTLQMTMRYAHLATHDLDSCVKVLEIH
>NC_017244.1|WP_004686530.1|648076_649210_-|pyridoxal-phosphate-dependent-aminotransferase
MAQPRLTPLVESLPSTVPFIGPETLELQRGKPFEARIGANENSFGPAPSVIEAMRNEATEVWKYGDPENYALRHAIAAHHGLKAEHIMPGAGVDALLGLIVRQYVQQGDKVINSLGGYPTFNYHVAGYGGQLVTVPYRDDKPDLDALIDAAAREKPALLYIANPDNPMGTWHGGADIQSFIERLPETTLLILDEAYCETAPASAFPPFETDRPNVLRMRTFSKAYGLAGIRCGYAVGNPVAIKTFDKVRDHFAVSRMAQAAAIAALKDQAYLHEVVGKICAGRDRIAAIAEANGLHAVASATNFVAIDCGRGKDFAQAVLNGLISRDIFVRKPGTPVLDRCIRVSVGVKEQLDQFEAAFPEALEEARKICAANAENT
>NC_017244.1|WP_002963792.1|659744_660416_-|uracil-DNA-glycosylase
MISEPSPNCSICPRLHAFLQEWRQKEPAWHNAPVPPFLPGSDEDVRLLIVGLAPGLRGANRTGRPFTGDYAGELLYSTLCEFGFATGKFEARPDDSLRLLDACIVNAVRCVPPENKPVGSEINNCRQFLTPMLTRFPNLDAVVTLGTIAHQSTVRALGVPVSRHPFGHGKATDIGPLRIFSSYHCSRYNTNTGVLTDAMFRDVFKNVRAYLSEKAAGSARLSV
>NC_017244.1|WP_004683386.1|660446_661022_-|NYN-domain-containing-protein
MFDSREKIALFIDGANLYAASKTLGFDIDYRKLLKAFQKRGYLLRAYYYTALVEDQEYSSIRPLIDWLDYNGYKVVTKAAREFTDSTGRRKVKGNMDIELTVDAMQLTDTVDHFVIFSGYGDFRSLVEALQRKGRKVSVVSTLTTQPAMISDELRRQADHFIDLVSLKAEIGRDPSERAPRRQEEDFDESY
>NC_017244.1|WP_002963795.1|661418_661820_+|DNA-directed-RNA-polymerase-subunit-omega
MARVTVEDCVDKVENRFELVLLAGHRARQISQGAPITVDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEAAPAQIANAAEEIAEGIAEAGEEDVVTFDRMSEEELLAGIEGLVAPEKNDGF
>NC_017244.1|WP_004685525.1|662060_664313_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MMRQYELVERVQRYKPDVNEALLNKAYVYAMQKHGSQKRASGDPYFSHPLEVAAILTDMHLDEATIAIALLHDTIEDTTATRQEIDQLFGPEIGKLVEGLTKLKKLDLVSKKAVQAENLRKLLLAISEDVRVLLVKLADRLHNMRTLGVMREDKRLRIAEETMDIYAPLAGRMGMQDMREELEELAFRYINPDAWRAVTDRLAELLEKNRGLLQKIETDLSEIFEKNGIKASVKSRQKKPWSVFRKMESKGLSFEQLSDIFGFRVMVDTVQDCYRALGLIHTTWSMVPGRFKDYISTPKQNDYRSIHTTIIGPSRQRIELQIRTREMDEIAEFGVAAHSIYKDRGSANNPHKISTETNAYAWLRQTIEQLSEGDNPEEFLEHTKLELFQDQVFCFTPKGRLIALPRGATPIDFAYAVHTDIGDSCVGAKVNGRIMPLMTELKNGDEVDIIRSKAQVPPAAWESLVATGKARAAIRRATRSAVRKQYSGLGMRILERAFERAGKPFSKDILKPGLPRLARKDVEDVLAAVGRGELPSTDVVKAVYPDYQDTRVTTQNNPAKAGEKGWFNIQNAAGMIFKVPEGGEGAAAKVDPAATTPKPGKRALPIRGTNPDLPVRFAPEGAVPGDRIVGILQPGAGITIYPIQSPALTAYDDQPERWIDVRWDIDDQMSERFPARISVSAINSPGSLAEIAQIAAANDANIHNLSMVRTAPDFTEMIIDVEVWDLKHLNRIISQLKESASVSSAKRVNG
>NC_017244.1|WP_002963797.1|664320_664899_+|orotate-phosphoribosyltransferase
MNTDDVLAVFREAGAILEGHFILTSGLRSPVFLQKARVFMHADKTEKLCKALAEKIRAADLGPIDYVVGPAIGGLIPSYETSRHLGVPSVWVERENGVFRLRRFDVPKGARVVIVEDIVTTGLSIRETIDCMKDLGIEVVAAACIVDRSAGKADVGTRLISLAEYEVPAYPADKLPPELAAIPAVKPGSRNI
>NC_017244.1|WP_014489380.1|665058_665814_+|helix-turn-helix-domain-containing-protein
MVVVPFALDQNQKLAARTPCNVCEDCCVRSMAVCSALDDGDLAALEAIMTSKKLDTNEMLVEEGEPKLRVYSLTSGMLRIYTSLPDGRRQIAGFLFPGDFLGLADDEVYSLLAEAVVPSALCAFSAKEMERLMERFPKLKERLYQMTRLALRTARDNQLVLGRLAPVEKLASFLLVLSARAEKRGEKPNPVHLLMNRTDIADYLGLTIETVSRSFTKLKTQGLIQLRDANTVEILSRRSLAVVAGLDPDNL
>NC_017244.1|WP_004686524.1|666194_667529_+|oxygen-independent-coproporphyrinogen-III-oxidase
MHDDAIRRYAALAVPRYTSYPTAADFVPVGMDTTRRWLRQIGPEESVSLYIHVPYCSQICHYCGCNAKMAIREDVIENFVNALLGEIRTVSASLTARPRVAHLHWGGGTPSILNAGQFQTVLAAIRTAFDFDLSMEHAIELDPRTVTPLLAKTLAEMGVNRASLGVQDVDSRVQMAIGRVQPIETVAEATRLLREVGINRINFDLIYGLPLQTVETLRETCERVVTLSPDRVACYGYAHLPQRRANQRLIDENTLPDADERFRQARIVTDSFIGFGYQPVGIDHFALPDDDLAIAAREGTLNRNFQGYTNDRCGTLIGFGPSSISQFPGGYAQNISDVGQYRKRVEAGELATVRGYTLRDADRIRSAIISALMCNFCVDLNAVAPGMEFSDEFALLRPLVADGLVAVEGRTIRATENGKSLIRLVAAAFDEFRRDSVHGFSFAV
>NC_017244.1|WP_004683395.1|667712_668924_-|MFS-transporter
MSVSAAQQPSNSSADNTVLTIILATSLGHFLNDMMQSLLPAIYPMLKENYSLSFWQIGLLTFTFQMTASILQPLVGIYTDRKPMPYSLTFGMGCTLIGLVFLATAHHYSFLLLGAACVGFGSSVFHPEAARVARLASGGRHGFAQSLFQVGGNFGSSIGPLLAAFIVLPFGQISVSWFSVAALIGMFVLWYVGNWYNRYRLANANKPKPDKTLPLPRNRVIASVAVLALLVFTKYIYMASLTSYYTFYTISHFGVSVQTSQLLLFLFLGAVAAGTIIGGPIGDKIGARKVIWASILGVLPFTLALPYANLEMTAVLTIIIGLILASAFPAIIVFAQELLPGRVGMLSGLFFGFAFGMAGIAAAVLGIVADQKGIEFVYRICSYLPFLGLLTIFLPKLERRRKA
>NC_017244.1|WP_002971501.1|669175_670015_+|helix-turn-helix-transcriptional-regulator
MPENEDLQRFHEHRIAMLESMTGPAIALPTRYPDGYFVPRHSHSRAQLLCASQGVVLVTTDAGRWMIPSDHAMWIPAGVEHSVAILGDVFMRSIYISVDAISGVPNYLHVVGLTDLMRCLIIDATSHDSIPAPESRDGLVIELILRDLHTLPEYPLGLPFPSDPRLQKLCRDFVKKPSSRATIDEWADRMAMSRRSFTRHFQRETGVSLSVWRQQACLFAAVPRLSEGEPVTSVALDLGYDSVSAFTTMFRRMLGVPPKFYQPRLDVAPFERSDKAAFG
>NC_017244.1|WP_002966733.1|670064_670640_+|DUF2062-domain-containing-protein
MLFQRRYPPTRWERLRLYLWPRRSFSRSFRYGGKRILRITASPHAVAAGLAVGVFSAFTPFFGFHLIIAIVLAYFLAGNVAAAALGTTLANPLTLPFIWGSTFELGRFIMSGSVDSVPPVHLGHALETMRFEEVWTPLLKPMLFGSTILGAAFAVLVYFVTRYAVSVFRRRRLERLAEKHRLHRQRELQKA

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017244_1	1.1|659649|27|NC_017244|CRISPRCasFinder	659649-659675	27	NZ_CP013986	Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence	45587-45613	5	0.815

1. spacer 1.1|659649|27|NC_017244|CRISPRCasFinder matches to NZ_CP013986 (Klebsiella variicola strain LMG 23571 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.815

ataagatgcgcgcaaggaaagatctgt	CRISPR spacer
aacagatgctctcaaggaaagatctga	Protospacer
*  ****** * ************** 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	875615 : 887527	13	uncultured_Mediterranean_phage(90.0%)	tRNA	NA
DBSCAN-SWA_2	958236 : 966575	11	Brucella_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017244|875615:887527|DBSCAN-SWA
CTTGGCAGCATCGGATGCACATACAGGTGGAAACGACGGCACACGCGTGCCGATGGATACCCTGTGGCAAAATGAGGCCGGGCGAGGCGCAGGCGAGCCGTCACTGCTGATCGATGTGCAGGGCTTTGAAGGTCCGCTCGACCTTCTTCTGCATCTTGCGCGTAACCAGCGCGTCGATCTTGCGCGCATTTCCGTGCTGGCGCTTGCCGAACAATATCTCGGTTTCGTGGAGCAGGCGCGCGCGCTGCGTCTGGAGCTTGCCGCCGATTATCTCGTTATGGCGGCATGGCTTGCCTATCTGAAATCCAAGCTGCTGATCCCGAAGCAGCAGGGCGACGATGGCGCCACGGGCGAGGAACTCGTTGCCTCCCTGCAATTCCGGTTGAAACGGCTTGAAGCCATGCGCGATGCGGCGGCGGCACTCGTCAATCGTCATCGGCTCGGCCGCGATGTTTTCCCGCGCGGCATGCCGGAAATGGTGGTGGTGGACCGCGCCAGCCGTTTTTCCGCAACGCTTTACGATCTGCTTAGCGCCTATGCGTCGCAGCGCCAGCGCCAGGCGGTTTCCCAGGTACAGATAGAAAAACGCAGCGTCTGGTCCCTCAAGGAGGCACGCACGGCGCTTGTGCGCCTGATGGGCGCGGTGGGCGACTGGGTTTCGCTGGACCGTTTTTTGATCGATTATGCACTTTCTCCGCAGGAGAGGGCGTCGGCGCTTGCCAGTTCTTTCGCCGCATGCCTCGAGCTGGTGCGCGAAGGCAAGCTTGAAGTACGCCAGAACGCTCCGTTCGAGCCGATCTATATGCGCGCGACCCGCGAACTCGATGAATTCGATGAGGACGAAAATGCCTGAAGCAGAGCGCCGCGATTTGATGGATATGGAAGGCGTTGGGGAAGAAGAGCAGGCGGGGCCTGCCTCGCCGGTGACGCTTGCCGAGCTTGCCCGCATTGTGGAGGCGATTGTTTTTGCGTCTTCGCAGCCTGTTTGCGAGCGCGCACTTGCCGAGCGGCTTCCCGCCAATGTGGATATTGCTCCGGTTTTGAACCATCTCCAGAAGGTTTACGAGGGCAGGGGCGTGCATTTTGTGAAGGTGGGCAGTGGCTGGGCGTTTCGCACCGCGCCAGATCTCGCCTTCATCATGAACCGCGAGACTGTTCAGCAGCGCAAGCTTTCGCGCGCGGCCATGGAGGTGCTTGCCATCATTGCCTATCACCAGCCGGTGACACGCGCCGAACTTGAGGATATTCGCGGCGTGGAAACATCCAAGGGGACGCTTGATGTCTTGATGGAAACCGGCTGGATCAAGCTGCGCGGGCGCAGGCGCACGCCAGGGCGCCCGGTAACATATGGCACCACCGACGCTTTCCTCGACCATTTTGGCCTGCCGGAAATCCGCGATCTGCCCGGTCTTGAGGAATTGCGCGGCGCAGGGCTTCTCTCGGCGCGCATTCCTTCCAGTTTTGCCGTACCGATCCCCAATATCGACCCGGACGAGCTGACCGAAGGGGAGGACCCGCTGGAGGATATTGATCTGGAGGGGCTGGGTTTGCTTGCACCCAGGGGAGAATAGAACAAAATTTCTGCCTGCGACGAATTAATCCGGTTTGAAGCCGTTCATCATCACACTTCTGTTTGAAAGATTTGTTGAAAGCGCTTAAATCGTATCGGAGATAGCAGGCATATGCCGCGCCTTGGGCGGCACTGAGAGGAATAATATGGGTAGCTTTTCCATCTGGCACTGGCTGATCGTTCTGGCGGTTGTGCTTCTTCTGTTCGGCCGCGGCAAGATCCCCGAGCTGATGGGCGATGTCGCCAAGGGTATCAAGAATTTTAAGCAGGGCATGGCTGACGAAGACGCCAAGGAAGATCCGCGTACGATCGACGCCAAAGCGGAAGAACCCGTCAAGGACGTCAAGAAGACCACCAAGTCCTGATCCTTCCGGGATGAACTGCCATGGGCTGAAAACGCGCATGGCAGGTTTGTGGGCAGTGCGGCTTTTCGCCAAGAGACAGGATGTGCGCGCAGAGCGCAAGGTATCAAATTATGTTCGATATCGCTTGGTCTGAACTGCTGATTATCGCAATTGTCATGATTGTGGTGGTCGGTCCCAAGGATTTGCCGAAAATGCTTCGCGCGTTCGGCAAGGCGACTGCACGCATGCGCACCACCGCCAACGAGTTTCGCCATCAATTCAACGAGGCCTTGAAAGAGGCGGAACTTGAAGACGTCAAGACCATCATCGATGAAGCCAGAAGCCTTGATCCGCGCACAAGGCTGACACAGGTTTTTGACCCGATTCGCAGTGCTGGCGAGGATTTGCGGTCTGGTCTCCAGTCCGCAACATCAATGTCGCCAGTCACCGAGAACAAGGTGGGTGAGGTTACGACGCCGGTTGAGCCGGGCGGAACGCCAGTTCCCGTACCAATGATCACCGCGCCCGAAGAACCCGCCAAGCCTAGGAAAACATCACCGCGTCCGGCTGCAAAAGCCGGGCCGAAACCGACGACGACAAAGACTGCCAAAAAAACCGGAGCTACCCCCAAGCCGACGGCAGACAAGACCGCAACGCCGGTTAAAAAGACCACAAAGAAGACAGGAACCAAAGCGTGAACCGGGACGAGGATGAAATCGAACAGAGCGCAGCGCCTCTGCTTGAACACCTGATCGAACTGCGCCGCCGCCTTATTTGGGCTATCCTGGCTTTTTTCGTGGCATTCATTTTCTGCTTTGCTTTCGCAAAACAGCTCTTCAACCTGCTTGTGGTGCCGTATCAATGGGCCATCGACTGGGCCGGCATGGACCGCTCCAAGGCGGAATTGATCTATACCGCACCTCAGGAATTCTTCTTCACGCAGGTGAAGGTGGCCATGTTCGGCGGCATTGTGCTGGCCTTCCCGGTCATCGCCGCACAGATTTATAAATTCGTGGCTCCCGGTCTCTACAAGCACGAACGCACTGCATTTCTGCCGTTCCTGATCGCGTCGCCCATTCTGTTCCTGATCGGCGGCGCGCTCGTCTATTTCTTTTTCACGCCCATGGTGATGTGGTTCTTCCTCGCCATGCAGCAGACCGGCGGCAGCGGCGAGGTCCAGATTTCGCTTCTGCCGAAAGTGTCGGAATATCTGAGCCTCATCATGACGCTCATCTTTGCTTTTGGCCTGGTCTTCCAGTTGCCGGTGGTGACGAGCCTCATGGCGCGTGTGGGGCTGGTGACTTCGGCGGGGCTGAAGGACAAGCGCAAATATGCGATCGTCATTGCCTTCGTCGCGGCTGCGGTGCTGACCCCGCCGGACCCGGCGAGCCAGATCGGTCTTGCCTTGCCGACGATCCTTCTTTACGAGATTTCGATCTTTCTGGCGCGCATGATCGAGAAGAAGCGGGATGAGGCGCAGGCATCTGCCGACGCTGATAACAACGCTTCCTCCACCTGATCTGACGTCAGGCATCTTTGGGGCTGAAGATCGTTTAGCCTCGCTTCTGTTCAATTTCACGAAATGGCTTTTTTCCATGCTCGACATCAAATGGATTCGCGAAAACCCGGAAACCCTCGACAAGGCGCTCGCAAAGCGTGGGGCTGCTCCGCTTTCGTCCGAACTGATTGCGCTGGATGAAAAGCGCCGCGAGCATGTCGGCAAGGTGCAGGCAGCGCAGGAGCGCCGCAATGCCGCCTCGAAGGAAATCGGCAAGGCCATGGCCGCAAAGGACATGGGCACGGCTGAAAAGCTGAAGGCCGAAGTGGGCGAACTGAAAGATTTTCTCGCCCATGCGGAAGAAGACGAGCGCCGCCTCAGCAAGGAACTGAGCGACGCATTGTCCACCATTCCCAATATTCCGCTTGATGATGTGCCGCTCGGCAAGGATGAAAGCGACAATGTTGAGCTGCGCCGCATTGGCAACCCGCACAATTTCTCCTTCCAGCCGAAAGAGCATTTTGAGCTTGGCGAGGCGCTTGGATACATGGATTTCGAGCGCGCGGCCAAGCTTGCCGGTGCGCGCTTTACGGTGCTGAAAGGCCCGCTCGCCCGTCTTGAGCGCGCGCTTGGCCAGTTCATGCTCGATCTTCACACGACAGAACACGGTTATACCGAAGTCATGCCGCCGCTGATGGTGCGCGACGAAGCGGTCTATGGCACGGGGCAATTGCCGAAGTTTTCAGAAGATCTTTTCCGCACGACGGATGGCCGCTGGCTGATCCCGACGGCGGAGGTGCCGCTCACCAATCTGGTTGCCGAAGAAATTGTCGATATGAAGGGGCTGCCGCTGCGCTTCACGGCGCTGACCCCATGTTTTCGCTCGGAAGCGGGGTCGGCCGGGCGCGATACGCGCGGCATGTTGCGCCAGCATCAGTTCCTGAAAGTGGAGATGGTATCGATCACCGATGCGGAAAGCTCCGTTGCCGAGCATGAGCGCATGACGGCTTGCGCGGAAGAAGTGCTGAAGCGGCTGGGCCTGCCGTTCCGTACCGTTGTGCTTTGCACGGGCGACATGGGCTTTGGCGCACAGCGGACCTATGATATCGAGGTCTGGTTGCCGGGGCAGAACACCTATCGCGAAATTTCAAGCTGTTCGACCTGCGGTGATTTCCAGGGCCGCCGCATGAATGCCCGCTATCGCCCGGAAGGCGAGAAATCCACGCGCTTCGTGCACACCCTCAACGGGTCGGGCGCTGCTGTCGGGCGCGCGCTGATTGCGGTTATGGAAAATTACCAGCAGGAAGACGGCAGCATTCATATTCCTGAAGCATTACAGCCATATATGGGCGGCCTCACGCGGATCGAAAAAGCCGCTTGATCTGGAATTATAGCATGCCCCCAAAAGTGGGAACCGGTTTTGGGGACATGCGAAAGAACAAAGAGAGAGCAGTTTCAACGATCCCATTTCAACTGGAACCGCTGTAGTGTCTTAAGTGTCTTATCCATTTCGGCGAAGGAGTGACAAATTGCGTATTCTGCTGACGAACGATGACGGTATCCACGCTGAAGGCCTCGCTGTTCTGGAGCGAATTGCACGCAAGCTCTCCGACGATGTGTGGGTGGTGGCCCCTGAAACGGACCAGAGCGGGCTTGCCCACTCACTGACACTGTCGGAGCCGCTTCGCCTTCGCCAGATCGATGCCCGTCATTTTGCCCTGCGCGGCACTCCGACCGATTGCGTCATCATGGGGGTGCGCCATGTATTGCCGGGCGCGCCCGATCTCGTCCTCTCCGGCGTCAATTCCGGGGCGAACATGGCCGACGATGTGACCTATTCGGGCACGGTTGCCGGTGCGATGGAGGGGACATTGCTTGGTGTGCGAGCCATCGCTTTGTCGCAGGAATATGAATATGCGGGCGATCGCCGGATCGTGCCGTGGGAAACGGCGGAAGCTCATGCGCCTGAGCTTATCGGGAGGCTGATGGAGGCGGGCTGGCCGGAAGGCGTGCTGTTGAACCTCAATTTCCCGAATTGCGCTCCGGAAGAAGTGAAGGGCGTGCGCGTCACGGCACAAGGCAAGCTTAGCCATGATGCGCGCCTTGACGAGCGCCGCGATGGACGTGGTTTCCCTTATTTCTGGCTGCATTTCGGTCGCGGCAAGGCTCCGGTTGCCGACGACAGCGATATTGCTGCCATCCGTTCGGGTTGCATTTCAGTGACCCCACTCCACCTTGATCTGACCGCTCATAAGGTTCGTGCAGAACTGGGCGCGGCGCTTGGAGTGGAAGCATGAGGCAGGCAACGTCTGAACGCCCGCGGCTTTCGGACCGGGAGGGATTTGCATCCTTTGTTCTGCGGATGCGTGGGCACAGCATTGATGATCCGCAACTTTTTGCGGCAATTGAAGCAACGCCGCGCCAGAGCTTTCTGGCGGCGGCATGGTCGCATCTTGCCTATAGCCCGCGAACCGCGCCGCTTGATTGCGGTGAATATATGGAAGGCATAGACGATCAGGCGCGCGTCATTTCCGCCCTGAAGCTTGAGCCCGGCCATCGGGTTCTGGAAATCGGCACCGGCTCCGGCTTTACCGCCGCCGTTATGTCCTTGCTGTCCGGCCGTGTAACGACGGTGGAACGGTATCGAAAACTCTGCGACCACGCTCTCCAGCAGTTCGTTTCGCTGAAGCGCGAGAATATCATGGTGAAACATACAGACGGGCGCCACGGTATGCCGGGCGGGCCGTTTGACCGCATTGTCATCTGGCTCGCATGCGATGAGGTGCCGCGCCATTTCGTTGAACTGCTCGCCACCCATGGCGTCCTGATAGCCCCGATCGGCCCTGGCGATGGACGCCAGATCATGACGCGGATTTCAAAGGTTGGAAGCCGTTTTGAACAGGAAGACCTCATGCCGGTTCGATATCAGCCGTTCATCGAAGGCACGTCTTCCGTTCTTTAGAGCGCATCCCGAAAAGTGTGAAACGGTTTTCGGAAAAGATGCGCGTCAAAACAAAGGATTAGAGCGCCGATCTGATTCAATCAGATCGAAACGCGCTCTAAAACGGGTTGAATTTAAGTCCAACCATCATCCCGCTCCAAGATTTTGTTTGAGGATGATTCCAAAAAACCGCTTCGCGCTTTTGTCGGAACGGCTTCAGTTGCATTGATTTTGAGCAATGGCAGCCTCGCCAGCTTGGCATTTGCGGGCCGGAAGTGGCTGTTTGCGCGTCATTCTTGCGCTTATGGTGTTTATTTGGTGAATCTTTTTTTAGTTTCGGGGCATTCTTAACCAGAGAGTAACATTAACGCGTTTTAATCGTCTTAGTGAGTTTCGAGTATGGACGAGTTGAACATGCGTTTACCAATTTTGCAGCATACGTCCGAACGTCTCCTGCGGAATGTCGCAATCGTTCTGATTGCCGGTTTTGGAGCCGGGTGCAGTGCTGATACGATGCGCTTCACAGACGGCATTTTTACTGGTTCTACGTCCAGTCAGCCCGTCGCGCAGCAACCCGCAGGCAATGTTTATGCGTCTGCCCCCGTGGCTTCGGCCCCGCCGGTTTCAAGCGGAACGGTCCAGCGCAATTCCTTGCCGCCGGTATCGTCAGCGCCTCTGGGTGCGCCTGTCGCTGCGGCATCGACGCAGATGCGCAATCAGGTCGATCAAGCCCAGGATATGGCGGCGTCCCGCGTCAATAATACCGTCAATGCCGCTGAAACCAGGGTCGCAAGTGCCGCCACCGTTACGCATAATACGGTGAATGGCGCGAAGGAAAAGGTTCTTGGCCAGCTTCCGGCGACGGGGCAGGGCGCGCCGCGCCCGATGGACAACAATATCGCTGGCGTTCCGCAAGCGCCTGCTGTCAACGGCAAGAAATCCTCGCCGACCAATATGGCATCGGCTGGCGGCGCTATCGCAACCCCGCCATCAGTGGGCGGTGCCTACGTCGTGAAGAGCGGGGATTCGCTGTTCTCCATCGCAAAGAAGCACAATGTCCCTGTCGACCAGTTGAAGGCGGCAAACGGCCTGACCAGTGGCGCCATTCGCGTCGGGCAGTCGCTCGTTATTCCGTCTGCTGCCGCAGGTGCGCCGACACAGGTGGCCGCAATCACGCCGCAGCCGGCAAACCCGGCCAAAGCAGCCAGTGCGCCGGCCAATGGAGGTGCAGAGGTAAAGCCTTATACGCCGCCGCAGGCCAGCAACAAGGTAATCGAGGATGCGGAAAAGGATCAGGCCGCAGCGCCATCCTCAACCGGCATCTCGCAGATGCGCTGGCCGGTTCGTGGGCGCATTCTGGCAAGCTTTGGCCAGCGTGAGGGCACCTCGGTCAGCGACGGTATCGATATCATGGTGCCGGAAGGCACGCCGGTCAAAGCCGCCGAAAACGGTGTTGTGATCTATGCGGGCGATGGTTTGAAGGAATTTGGCCAGACCGTTCTGATCCGCCACGACAATGGCCTTGTGACCGTCTATGGCCATAACAGCCAGATAATGGTGCAGCGCGGCCAGAAGGTTCGCCGTGGCGAGGAAATCGCCAAGTCGGGCATGAGCGGCAACGCCAAGTCGCCGAAGCTGCACTTCGAGGTGCGCAAGAACTCGGCGCCGGTCAATCCGACCAAATATCTGGAATCATAACAGTTTCAGCAGGAAAAAATGAAAAAGGCGGGCAGGGGCCCGCCTTTTTCATTGCATGGTTTTTCCAAGCCTGCCTGCCAGATCCTGAATATATTGCCACGCAACACGGCCCGAACGGTTGCCGCGTGTGGTGGACCATTCCAGGGCTTCCCTGTGCATCTGGTCGCGGGCATAGTCGAGTTTGAAATGCGCCGCATAGCCGTCGATCATGGCAAGATAATCGTCCTGGCTGCATTTATGAAAGCCGAGCCACAGGCCGAAGCGGTCCGACAGTGAAACCTTTTCCTCGATGGCTTCTGAGGGGTTGATCGCCGTCGAGCGTTCATTGTCGATCATGTCGCGCGGCATCAGGTGGCGACGATTCGATGTTGCGTAGAAAATCACATTGTCGGGGCGTCCTTCCACGCCGCCTTCAAGTGCTGCTTTCAGCGATTTATACGATGTATCGTCATGATCGAAGGATAGGTCGTCGCAGAACAGGATGAAACGATGGCGCGTTTCCTTGATGAGATTCATCAAAACCGGCAGGCTATCGATATCCTCACGATGAATTTCGACAAGCTTCAGCGGTGTTATATCCGGAAATTCGGCGTTCACGCTCGCCTGCGCGGCCTTTACGAGCGATGATTTACCCATGCCGCGCGCGCCCCAAAGCAGAACATTATTAGCGGGAAAACCTTTTGCGAAGCGGCGGGTATTGTCCACAAGCTGGTCACGTACCAAATCTACGCCACGGATCAACGCGATATCCACGCGGTTCACACGGCTGACGGGATCGAGAACAAGCCGCTCCGGGGCCCAGACGAAACAGTCTGCGGCGTCGAGATCGGGTGTTTTTGCTTCCGGCGGTGCAATGCGTTCCAGCGCGGCTATCAAACGGTCCAGTTTCTGGCTGAGTATATCTTCGGTCGTCATTTTAGGCCCCTGATGGTAGGGGTAACGACTTAACATGCTAACGCGGAAGCGAAAAGTGTGCGACCTTGGCGCAGGCGGGTTCATCGCCGGTTGCAATTGAAGCACCAACCATTGTAATGCCGTTAATAATTTGTCTTCGTGACTTCAGAGGAGTTCCTAATGTTCGTAACACCGGCTTTCGCTCAAGCATCCGGCAGCGTTGTTGGACCAGATATGCTCATGAGCATCCTGCCGTTCATCCTGATCTTCGTCATCATGTACTTTCTCATCATCCGCCCGCAGCGGACCCAGATGAAGAAGCGTCAGGAAATGCTGAACTCCGTGCGTCGTGGCGATACGGTCGTGACGGGTGGCGGCATCGTCGGCAAGGTTCTCAAGGTTGTCGATGACAACGAACTCGAACTCGAAATTGCCGATGGCGTTCGTATTCGCGTTGTGCGTGCCACCTTGATGGATGTGCGCGTGAAGGGCGAACCTGTCGCCGACAACAAGAACAAATAATCTCTTTTTTTTGAAAGAGCAGGCGGGCTCCGGTAAGGTTTAAATAACCTGAGCCCGTTCATTATGCAGCACGCGCGCAAAATCGCGTTTGCGTGCAAATAGCCGGAAGATTTTCCCTTTGGGTGAACTCCGGCAATGCTTCATCCAAGCTGAAACGGACTTGCATTCCATGCTCTATTTTTCACGCTGGAAATCTGCACTGATATGGCTGGCAGTCCTTGTCAGCCTCATCATCGCATCTCCAAATTTTTTCTCGCGTGAAACGCTGGCAAATCTGCCGGATTTTCTGCCCAAGAAGCAGGTATCGCTGGGGCTCGACCTTTCGGGCGGTTCGCGGCTTATTCTTCAGGTGCAGAATGCAGGCAAGACCGATCTGGAGACGACTGCCAATATCATGCGGCAGCGTCTGGAAGAGCTTGGCTATGGCAATCCCGTTGTCGAGGGAGAGGGGCGCAATCAGATTCGCGTGGAGGTTCCGGGCCTTTACGATGCGCAGCTTCTCAAAGATATTCTCACCATTCGCGGAAATCTTTCCTTCCGCGCCATGGACGACACCATGTCGCCGGATGACGCCATTCGCGGCACACCGCTTGCCGATAGCGAAATCGTCTATTCCTTTGATGATCCTCCGGTTGGTTATCTTCTGAAAAAAACACCCATTCTCACCGGGCATGACATCACGGATGCCAAGGCGAGTATTTCCGCCGACGATGGCCAGCCGGTCATCACGCTGACACTGGACGACAACGGACGCCGGCGTCTGGCCGATCTGACGGCGCAGGGCAATGAGAATTCCTTCGCCATCGTCGTTGATAATCAGGTGGTTTCCGCGCCCACGGTTTCCGGCCCGCTCGACACCAGTGAATTGCAGATCGAAGGCGCATTCGATTTACAGGCCGCCAATAATATGGCCGTGGTTCTGCGCTCTGGCGCCTTGCCGCAAGCGGTGACTGTGCTTGAAGAGCGCACCATCGCCTCCGCGCTCGGTGAGGATTATGCGAGTGCGGCAGTGCTTGCGGCCCTTCTGGCGGCACTGGTGGTCGGCCTCTTCATGGTGCTTTCCTATGGCATTCTGGGTGTCATCGCCCTGGTTGCGCTTGTGGTCAATATCATCATCCTGACGGCTGTTCTGTCGCTCATTGGCGCTTCGATAAGCCTTGCGAGCATTGCAGGTCTCGTCTTGACCATCGGCCTTGCGGTCGATGCGCATATTCTGATCTATGAGCGTGTACGCGAGGATCGCCGCAAGGGCTATTCCGTCGTGCAGGCGATGGAATCGGGCTTTTATCGCGCCCTTTCCACCATTGTGGATGCCAATCTTACCACGCTTATCGCCGCACTCGTTCTGTTCCTTCTGGGGTCGGGTACGGTGCATGGTTTTGCGCTCACGGTCGCAATCGGCATCGGCACGACGCTTTTCACCACGCTCACTTTCACGCGCCTGCTGATCGCCCAATGGGTGCGCACCGCCAAGCCGAAGGAAGTGCCCAAGCGTCGCCTGAAACTGGTGCCAACCGTCACTCATATTCCCTTCATGCGCCTCCAGTTCGTAACGCTCGGCATTTCGGTGCTGGCCTGCGCAATCGTGGTCGCGCTTTTCGTCAATATCGGCTTCAACTACGGCATCGACTTTCGTGGCGGTTCGATGGTCGAGCTGCAGGCGCGCAATGGCGATGCCAATCTGGAAGATATCAACGAGCGGCTCGCGGAGCTGAATATCGATAGCGCCCGCGTTCTGCCTGCGAAATCGCCGCGCTCGGCCCTTGTCATTATCGGCAGTCAGGAAGTGGGCGACGATGCGGAGCAGACCGTTGCCGTCAAGCTTCGCGGTGAATTCGAGCAGGATTATTCCTTCCAGCGGGTCGATGTGGTCGGGCCGACCGTATCGGAACAATTGTCGCGCGCAGGCGTGCTCGCTGTCATCCTGTCGCTGATTGGCATCTTCATCTATGTCTGGTTCCGCTTCCGCTGGCAGCTCGCACTGGGCGCGGTGCTTTCCACATTGCATGATGTCGTCATTCTTTCAGGCATGTTCATCGTTTTCCGCATGGAATTCAATTTGTGGAGCGTGGCGGCAATCCTCACGATCATTGGCTATTCGCTGAACGATACGGTGGTGATCTATGACCGGGTGCGCGAGAACCTTCGCCGTTACAAGAGTGCGCCATTGCCCGCGATCATCGATGCCTCGATCAACCAGACCCTGTCGCGAACGCTGTTGACCTCTTTCGTCACCTTCCTGGCACATGTTCCGCTTTATGCTTTTGGCGGCTCGGAAATTCGCATGTTTGCGCTGGCGCTCAGTGTCGGTATCATTGTGGCGAGTTATTCTTCAATCTTCATCGCAGCACCGCTGCTTGTTCAGTTCGGTCTCAAGCCGCGCGAAACCGATGCCGGTGACGCGGTGGATGCGGAGCTTGCGCAATCGCTCAATCTGGAAAGCTGA

Protein sequences of DBSCAN-SWA_1

>NC_017244|875615:887527|876459_877185_+|WP_002964011.1|DBSCAN-SWA
MPEAERRDLMDMEGVGEEEQAGPASPVTLAELARIVEAIVFASSQPVCERALAERLPANVDIAPVLNHLQKVYEGRGVHFVKVGSGWAFRTAPDLAFIMNRETVQQRKLSRAAMEVLAIIAYHQPVTRAELEDIRGVETSKGTLDVLMETGWIKLRGRRRTPGRPVTYGTTDAFLDHFGLPEIRDLPGLEELRGAGLLSARIPSSFAVPIPNIDPDELTEGEDPLEDIDLEGLGLLAPRGE
>NC_017244|875615:887527|881319_881988_+|WP_004683704.1|DBSCAN-SWA
MRQATSERPRLSDREGFASFVLRMRGHSIDDPQLFAAIEATPRQSFLAAAWSHLAYSPRTAPLDCGEYMEGIDDQARVISALKLEPGHRVLEIGTGSGFTAAVMSLLSGRVTTVERYRKLCDHALQQFVSLKRENIMVKHTDGRHGMPGGPFDRIVIWLACDEVPRHFVELLATHGVLIAPIGPGDGRQIMTRISKVGSRFEQEDLMPVRYQPFIEGTSSVL
>NC_017244|875615:887527|880555_881323_+|WP_004683703.1|DBSCAN-SWA
MRILLTNDDGIHAEGLAVLERIARKLSDDVWVVAPETDQSGLAHSLTLSEPLRLRQIDARHFALRGTPTDCVIMGVRHVLPGAPDLVLSGVNSGANMADDVTYSGTVAGAMEGTLLGVRAIALSQEYEYAGDRRIVPWETAEAHAPELIGRLMEAGWPEGVLLNLNFPNCAPEEVKGVRVTAQGKLSHDARLDERRDGRGFPYFWLHFGRGKAPVADDSDIAAIRSGCISVTPLHLDLTAHKVRAELGAALGVEA
>NC_017244|875615:887527|884739_885081_+|WP_002964021.1|DBSCAN-SWA
MFVTPAFAQASGSVVGPDMLMSILPFILIFVIMYFLIIRPQRTQMKKRQEMLNSVRRGDTVVTGGGIVGKVLKVVDDNELELEIADGVRIRVVRATLMDVRVKGEPVADNKNK
>NC_017244|875615:887527|885199_887527_+|WP_014490079.1|DBSCAN-SWA
MGELRQCFIQAETDLHSMLYFSRWKSALIWLAVLVSLIIASPNFFSRETLANLPDFLPKKQVSLGLDLSGGSRLILQVQNAGKTDLETTANIMRQRLEELGYGNPVVEGEGRNQIRVEVPGLYDAQLLKDILTIRGNLSFRAMDDTMSPDDAIRGTPLADSEIVYSFDDPPVGYLLKKTPILTGHDITDAKASISADDGQPVITLTLDDNGRRRLADLTAQGNENSFAIVVDNQVVSAPTVSGPLDTSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVLAALLAALVVGLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLIAQWVRTAKPKEVPKRRLKLVPTVTHIPFMRLQFVTLGISVLACAIVVALFVNIGFNYGIDFRGGSMVELQARNGDANLEDINERLAELNIDSARVLPAKSPRSALVIIGSQEVGDDAEQTVAVKLRGEFEQDYSFQRVDVVGPTVSEQLSRAGVLAVILSLIGIFIYVWFRFRWQLALGAVLSTLHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSAPLPAIIDASINQTLSRTLLTSFVTFLAHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLLVQFGLKPRETDAGDAVDAELAQSLNLES
>NC_017244|875615:887527|875615_876467_+|WP_004683698.1|DBSCAN-SWA
MAASDAHTGGNDGTRVPMDTLWQNEAGRGAGEPSLLIDVQGFEGPLDLLLHLARNQRVDLARISVLALAEQYLGFVEQARALRLELAADYLVMAAWLAYLKSKLLIPKQQGDDGATGEELVASLQFRLKRLEAMRDAAAALVNRHRLGRDVFPRGMPEMVVVDRASRFSATLYDLLSAYASQRQRQAVSQVQIEKRSVWSLKEARTALVRLMGAVGDWVSLDRFLIDYALSPQERASALASSFAACLELVREGKLEVRQNAPFEPIYMRATRELDEFDEDENA
>NC_017244|875615:887527|882366_883665_+|WP_002964019.1|DBSCAN-SWA
MDELNMRLPILQHTSERLLRNVAIVLIAGFGAGCSADTMRFTDGIFTGSTSSQPVAQQPAGNVYASAPVASAPPVSSGTVQRNSLPPVSSAPLGAPVAAASTQMRNQVDQAQDMAASRVNNTVNAAETRVASAATVTHNTVNGAKEKVLGQLPATGQGAPRPMDNNIAGVPQAPAVNGKKSSPTNMASAGGAIATPPSVGGAYVVKSGDSLFSIAKKHNVPVDQLKAANGLTSGAIRVGQSLVIPSAAAGAPTQVAAITPQPANPAKAASAPANGGAEVKPYTPPQASNKVIEDAEKDQAAAPSSTGISQMRWPVRGRILASFGQREGTSVSDGIDIMVPEGTPVKAAENGVVIYAGDGLKEFGQTVLIRHDNGLVTVYGHNSQIMVQRGQKVRRGEEIAKSGMSGNAKSPKLHFEVRKNSAPVNPTKYLES
>NC_017244|875615:887527|877330_877549_+|WP_002964012.1|DBSCAN-SWA
MGSFSIWHWLIVLAVVLLLFGRGKIPELMGDVAKGIKNFKQGMADEDAKEDPRTIDAKAEEPVKDVKKTTKS
>NC_017244|875615:887527|877659_878226_+|WP_006094283.1|DBSCAN-SWA
MFDIAWSELLIIAIVMIVVVGPKDLPKMLRAFGKATARMRTTANEFRHQFNEALKEAELEDVKTIIDEARSLDPRTRLTQVFDPIRSAGEDLRSGLQSATSMSPVTENKVGEVTTPVEPGGTPVPVPMITAPEEPAKPRKTSPRPAAKAGPKPTTTKTAKKTGATPKPTADKTATPVKKTTKKTGTKA
>NC_017244|875615:887527|879123_880407_+|WP_004683702.1|tRNA|DBSCAN-SWA
MLDIKWIRENPETLDKALAKRGAAPLSSELIALDEKRREHVGKVQAAQERRNAASKEIGKAMAAKDMGTAEKLKAEVGELKDFLAHAEEDERRLSKELSDALSTIPNIPLDDVPLGKDESDNVELRRIGNPHNFSFQPKEHFELGEALGYMDFERAAKLAGARFTVLKGPLARLERALGQFMLDLHTTEHGYTEVMPPLMVRDEAVYGTGQLPKFSEDLFRTTDGRWLIPTAEVPLTNLVAEEIVDMKGLPLRFTALTPCFRSEAGSAGRDTRGMLRQHQFLKVEMVSITDAESSVAEHERMTACAEEVLKRLGLPFRTVVLCTGDMGFGAQRTYDIEVWLPGQNTYREISSCSTCGDFQGRRMNARYRPEGEKSTRFVHTLNGSGAAVGRALIAVMENYQQEDGSIHIPEALQPYMGGLTRIEKAA
>NC_017244|875615:887527|882132_882318_+|WP_002964018.1|DBSCAN-SWA
MFEDDSKKPLRAFVGTASVALILSNGSLASLAFAGRKWLFARHSCAYGVYLVNLFLVSGHS
>NC_017244|875615:887527|883713_884580_-|WP_002964020.1|DBSCAN-SWA
MTTEDILSQKLDRLIAALERIAPPEAKTPDLDAADCFVWAPERLVLDPVSRVNRVDIALIRGVDLVRDQLVDNTRRFAKGFPANNVLLWGARGMGKSSLVKAAQASVNAEFPDITPLKLVEIHREDIDSLPVLMNLIKETRHRFILFCDDLSFDHDDTSYKSLKAALEGGVEGRPDNVIFYATSNRRHLMPRDMIDNERSTAINPSEAIEEKVSLSDRFGLWLGFHKCSQDDYLAMIDGYAAHFKLDYARDQMHREALEWSTTRGNRSGRVAWQYIQDLAGRLGKTMQ
>NC_017244|875615:887527|878222_879047_+|WP_002964014.1|DBSCAN-SWA
MNRDEDEIEQSAAPLLEHLIELRRRLIWAILAFFVAFIFCFAFAKQLFNLLVVPYQWAIDWAGMDRSKAELIYTAPQEFFFTQVKVAMFGGIVLAFPVIAAQIYKFVAPGLYKHERTAFLPFLIASPILFLIGGALVYFFFTPMVMWFFLAMQQTGGSGEVQISLLPKVSEYLSLIMTLIFAFGLVFQLPVVTSLMARVGLVTSAGLKDKRKYAIVIAFVAAAVLTPPDPASQIGLALPTILLYEISIFLARMIEKKRDEAQASADADNNASST

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004683698.1|875615_876467_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.4e-31	33.5
WP_002964011.1|876459_877185_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.5e-43	45.7
WP_002964012.1|877330_877549_+	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	1.5e-07	65.1
WP_006094283.1|877659_878226_+	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_002964014.1|878222_879047_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	9.8e-44	41.1
WP_004683702.1|879123_880407_+|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.6e-104	47.2
WP_004683703.1|880555_881323_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.0e-39	40.2
WP_004683704.1|881319_881988_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	6.6e-14	38.5
WP_002964018.1|882132_882318_+	hypothetical protein	NA	NA	NA	NA
WP_002964019.1|882366_883665_+	peptidoglycan DD-metalloendopeptidase family protein	Q8SBN9	Clostridium_phage	1.0e-18	41.1
WP_002964020.1|883713_884580_-	ATP-binding protein	NA	NA	NA	NA
WP_002964021.1|884739_885081_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	9.1e-12	40.2
WP_014490079.1|885199_887527_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	6.2e-51	43.5

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017244|958236:966575|DBSCAN-SWA
CGTGAGGCGTTTCGGCTGCTTGTCCTTGGTGGCAAGCTTGGAAGACGGACGCTTCACGCCTTTGAACTTCGCTTCCCGGCGCTTCGCCTACCGGGAAGAGCGTTACAGGCGTAACAAAGCGTCACAAGTGACGCAAAGTGACGCCACAGAGGAAATTCAAAAAGAAGGGTTTCCCCATACCCCTTCCGAAGAAAATACCCCTAAAGAGGTCCAAAAGAAATCCCCCCGTTCGGTACTCGAAGCTGTCCTTTCCCAGCCGATAGCCGTCGCAGTGGTCGAGCACAGGGCCAAGATCAAAAAACCTTTGACCGAGCGCGGTGCTGAACTGCTCGCCAAGCGGCTGGCCGCCGCAAAGGATGCCTGCGGCCTCACAGCCGATCAGGCGGCGGACCCGATGATCGAGCGCGGATGGCAAGGCTTCGACGCGGAATGGGCGAAAAATGCCATGCAGTCTGGGTGGAAGCCGGAAGCCCAGCGACAGGCCAGCAGCTACAAGCCGGACAGCGAGCTTTCCCAGGAGGAACGCGACGCCCGCTGGAAGAAATTCATGAACTACGCCCGCAACAATCGGTGTTGGCACTCTGACGTGTGGGGGCCGATGCCGAATATGCTGGGTTGCCGCGTCCCTGCGCATCTCATCCTCCCGACAGATGGTCGAAAGTCGAACGGCGACCCGTGGACGGAGCAGGGGAGGATTGCAGCATGATCGCCGCCTATCACGCAAAAACTGACCGTTCGGCGTCGTATTACTGGTCGAAGAAGGATCAGGAAATTTTCAAGCCCTTACGCCTTTTCCGACAGGGCAAAGACACGCTGGAAATAGCTGAAATCATGGGCATCACCGAAGCAGATGCTCTCATGCGTGTTCACAGAGCGATCAGTTCCACGAAGCGCAAGAAGGTCCGCACCGTTCCACATGGAGAGCTAGCATGACGCCGGAGACTGCATTGATCAACGAGTACCTCGCCAAGCATGGTGCACGCCGGTTCGAGCAGGGCGCCACCAGTGGCATTCACGGGATAGCGTCATTCATGGCTGAATATGGCTACGAGGTAGCCGGAGCACCGAAAGGCGGCGTCAAGGTTCGTCGTGGCAAAGGCCAGTGGAAACGTATGTCCATGCCAGGGCTAATCGCAATGGCAGATGAAATTCGCCTTGCGCAGGGGCTTGAGCCTTTCAGCGCAGCGCACAAACAGGCAGCATAACCCCAGTCAGCGAGGAACGGACATGGCGAGGACGAAAGCGGCGAAGCTTCAAGCCAAGCGGTCGAGAGGAAGGCCAAAGAAGGAGGGAGTTTTGCGCGCACCTTCCGGTCAGATCAGCAGGGCAAAGGAACCGCCCGCAAAGGTGGCGCAACTGGCAAGGATGAGGATATTCGGCATGAGCGCATCGGAAGCATTAAGCGACTTGGCGGGGGATAATCTGGGGCGCTTGCATATGGCATGGAAGCGAGACAAGGCGGAGGGCATCAGCACGAGCCAGTATGACGCCGCAGAGCGCTACAGGGAAGTTTTCAACGACAAGCGTAAGGCGGAGTGTTCCGCTGGCGCGCACTATGACCACATAGGTTCGATTGGTGCTTCCGACCCCGATGAGTATGAGGCGTGGGTAAAGCGCGCCAAGCAGGCTTATGCCGACGCTCGTGGGGCAATAGATGAAGCACAGGCCGAAACGCGAAATAGCAATCTCTATGCTGCCGTTTAATTCATGCTTGAGAATGATCAATTCCTCCCGCATATGCTTGGAGATATTCGTCTCGCCTGTAACGCACTTTATCGTCATTTTTTCACACATAACCGCAAGAAGGTCGCATGATTGTCTTTCCATATCGAGCAAAGCAGAATAATCTGCGCATAGTTTCAGGATGCAGAATTGCGACATGAGGATTACAGCGGCTTTTCGGGCCGCTTTTTTACTGTTTGGTTACTATGAAATGTGTGGCGTTCAGTATGAGCGTTATGGTTGCAAGTGTTGCTGAAAAACTACAGACATTTCACTCGGATGATATAATTAAGAGATCAATGAATATTGGAATGTTTGGAGGGAACCGTGAACATTAAATCGCTTCTTCTTGCATCAACTGTCGTTCTCGTTGCTGCGACTGGCGCAAAGGCTGCTGACGCCGTCATTGAACAGGAACCTGCACCGGTTGTTGTTGCTCCGACCTTCACCTGGAATGGCGCCTATCTCGGCGGCCAGATCGGTTATGGTTGGGGCCGTTCGACGCTGAGCGATGAAGACACATCTATCCGAGTAAAGCCAGACGGTTTCCTCGGCGGTCTTTATGCCGGTTATAACTTTGACATGGGGAACAACTTCGTCCTCGGTGTTGACGGTGACATTACCTATAATGATCTAGATGCTAGCCACAGTGACACCGACCCAGATCTTGATCTCACCACTGGTGTTGACAGCAAGCTCCGCTGGTCAGGCGCTGTTCGCGCTCGCATGGGTGTCGCAATGGATCGATGGATGCCATACATTGCCGGTGGTGTGGCCTTCGGAAACGTTAAGAATTCAGTTTCACTCACGGACGGTATAGAGAGCATTGGGGTTTCTCAGAGCAAGACTATGACTGGCTGGGCCGCTGGCGCTGGTGTTGATTACGCGGCAACTGACAATGTCATCGTACGTCTTGAATATCGTTATACCGACTACGGCCATAAGGATTTCAGTGTAGTTGATGGCGATCTCAGCGTTGAGGCTCGCAACAAGTTTAAGACACACGACATCCGATTGGGCGTAGCTTACAAGTTCTAATCTGATATTTGATCAGATATAGAGCCGCCTTGTTCGCAGGGCGGCTTTTTTATTCGAGGCTCTGCCTCAACGGAATGCGATGGCGTTTCGCACATCGAGCGCCGATCCTCGCATGTAGCTGACGGCCAGCGAAGATAGCCGTAGTTGGAGAATGGGTCTGGGGAAGTCCTCGTAGCCAGACGGCTCGAAAGAGCGCCGACTAGGGCAGATATTCGCCCTCATGCAGTACCGCCCCACTTATCAGGGTAGCGCGAGACATGAGGGCAACGGAATTAGAACGGCGGCGCACCAGATAGTAACGGAAGCCAAGAAGCCAGTGGCTGGTGCGCAACGCTTGGTCGTTGTGATTATCTCTCGACTACAGGGGCAGCGGCAGAGCTCTTGACGAGATTAATGCCATTTATCGCATCAGCTCTGTTCACGTATCCCTCGCCACTGTCGGCAATAGTTCGGTGATTGTTGGCCAGAAGACGCCAGCGCCAGTACCCGGCGTTATCTCGATAAAGGACGTATTGCATGTCTGTCTCCTCCAAGAATGATGTGTTTCGTAAATTCCTTTTCAGCTATCGATATGATGGCGCTAAATGGAGCATTGAAATACAGGCGCGTTCTGTCGACGAAGCCAGAAAGCGCATATCGTCCCTCGCACTCGCTCGATACGATGGCGAGGTGTTCGCTCGTTATCCAGCAACTGTCGGATTTATCCCCCGCATGATTGCGTTTTTCCGAAACGCACGGTTGGCAGCTTAACCAAAACGGATTGGTTGTAAACGGGTCAAGAAATTCAACCTTAGTCTCAGCCAGCATGGGATGAAAAGGGACCTCCGAAGTGTCGCCGCTTCTCAAGCCACAGGTCACTTGCTGATCAAAGCCCGACAGCTTTGCGCAGGGCATCGTTCATACGGCCCTGCCAGCCTTTGCCGGTGGCCTTGAAGCGTTGAACTACATCCTGATCGAGCCGGATAGTAACCGGCGTCTTGGGATTGTCGATGCGCGGCCGGCCTCGAATGGCCTTCTCCATCTTGGCGGCCATATCTGGAAAGGATTCCTTGAAAGGCTTGGCCTTGGCAAGCTGTTTATCGGTGGCTTCCGGTGCATCGGGATCGCTTGCGATCATCTTCTGAATTTCTGCCTCTTCCTCCTGAGTGAGAGGGCGCTTAGAGGAAAATTTGATACCCATCAGAGCTTCCTTTCCTTCTGGCTTGCTGAACGCATGGAGATCACGGAGAGGGCTTCCGAACCAACCGGCTTGAAAATGACGGCGATGATAATCAGGCCGTTGAATTCTCCGATTGCCATCAGGCGATCTGCCTTGGTGGGGAAGACCTTAGCCGACAGGAAGAATTCGAAATGCAGGTCAGCGAAGTCCAAGCCGTGCTTGGCAATGTTGGTCTGTCGCTTCGGTTCGTCCCAGATGATCTTCATAAAACGTATGTACAATAATTCGTCTGGGCTTGCAATAATAATCGTACATACAAATAATATTTTCTGTACGTACACGTGAGGGTATTATGAACCGCCGTCGCTTCCTTTCCTTCCTCGGCCTTGCTCCTGTAGCTTTCGCTGCGCTGGGCCGAGCGTTGCAAGGTGGCATTCGGCGACCAGCCGGGCAAGGCCATGTTCGGCATCGTGCAGGGGGGCGATATCGCGCGTCTGCGCGAAAGATCGGCAGAAGCGCTCAAGGCCATGGACCTCAAGGGCTATTCGGTTGGTGGGCTTGCGGTGGGCGAGCCGCAGGAAGTCATGCTGGATATGCTGGAAGTGGTCTGCCCGATCCTGCCAACGGAAAAGCCGCGCTACCTGATGGGGGTCGGCACGCCAGATGATATTTTGAAATCCGTGGCGCGCGGGATCGATATGTTCGATTGCGTGATGCCGACGCGCGCGGGGCGCCATGGCCTTGCTTTCACCCGCTTCGGCAAGGTGAATTTGCGCAATGCGCGTCATGCGGAAGATCATCGCCCGCTCGATCCGCAATCCGATTGTCCGGCATCGCGCGATTATAGCCGCGCCTATCTGCATCATCTGGTGAAGTCCGGCGAGGCGCTCGGTGCAATGCTGCTCACCTGGAACAATCTTGCCTATTATCAATATCTCATGAAGGGCATTCGCGCGGCGATTGCCGATGGAAATTTCAGTGATTTTACCGCTGAAACCACGGAAGGCTGGGCAAGAGGCGATATGCCTGCGCTCTAGGGCCTGTCTGCATACAAGGATTCCCTTTTGCATGAAATTCTGATTCAAGGTTGTTGAAGGAGAACAGCCTTGAGCAGACGAAGCTTTACAGATGAGCAATGGAACCGGATCGAAGCATATCTTCCGGGGCGAGTTGGTACGCCCGGCCGCAGTGGCGTTGATAACCGATTATTTGTCGACGCCATCTTGTGGATGGCTGCCAATGCAGCGCACTGGCGCGATCTGCCTGCGACCTTCGGCAAATGGACAGCGGTTCATGCCCGCTTTCGGCGCTGGTCGCACGCCGGTGTATGGGAAAGGCTTTTCCATGCCCTGGCTGATACGCCGGACTTTGAATATGTCCTCATTGACAGCACCATATCGAAAGTCCACGCAGATGCGGCGGGCGCAAAAGGGGGGCTGAAGCTGCCTGCATCGGTCGCTCGCGCGGGGGATTGACGACCAAGCTGCATGCTGTTGTCGATGCTATCGGCCTACCGCTGCGAATAAAGCCAACACCCGGCCATTATGGTGACTGTCCGCAAGCTTCAAGCCTTCTATCCGGCTTGAAGGGTGTGGGGCATGTCATTGCTGATGCGGCCTATGATGCCGATCACTTAAGGGCCTTCATTGCCAGCGATCTCAAGGCAACGGCTCAGATCCAAGGCCAATCCAACACGTTCCAGTGCCCCAACAATCGACTGGAGGCTGTACAAGGAACGCCATCAGATTGAATGCTTTTTTAACAAGTTGAAACGCTATCGTCGTATTGCGCTGCGATGCGAGAAAACATTGACCGCATTCATGGGTTTCGTCCATCTCGCATGCGCTATGATCTGGTTACGTTGAATGCAGACACGCCCTAGGGCGAAGTTCTACCAGCAGATGACCGCTATTGGGGCCATGACTATCAATGAGGTCCGGTCTTTGGAAAACTACCCGCCGGTTGGCCGTGACGTGATGACAACGGCAAACACGATCCGGGCAACATTCCTCGACATCAATCAAGATTATCAGGCGTCTGACGCAGATCCTTGGGCTGATGAGGCCGATGTATCGGAGCGTGGTGAAGAAGCCAAAGATGTTCAATTCAATATGGCTCCTTCGCACAGCCAGGCAAGACGCTTGATGAAGCTCGAATGGTTCCGAGCTAACCCGAATTGGGTAGGGACGTTCAACACGAACCTGATGGGCCTTGCTGCTTTCGGCGAACGGTTGATCGGCATCCAATACCCGCTGTTCGGAATTAACAGTGTTTTTGAAGTCCTTGATTTCAAATTCATCCTTGGTGAAGGAGGCATTCTGCAAGGGGCGACCATTCAGGTCCAGTCCATGACGGACACTGCTTACCAGTGGGACACATCGCAGGAAGGCACAGCGCCGGTATCGGACGAAACTACTTCGGACGATGATTTGCCAGTTCCAGACGCGCCAGATGTTCTGATTATCGCTGGACCAGCAGCAGAACTGAGCTTCCCGCCTACCGGCAACATCCTGTTGAACTATATGGTCCGCTGGAAAAAGACGGCTGATACCGAATAGCGTGTGGCTGGTCCGCTCGAAAACGACGCAGAGAGCTTTGAAACACCGACGCTGTCAGCGCTGACACAGTACGAGTTCTAATTGGCCGTTCGTACCCAGAAGGGACGCGTAGGCGCTTACTCGGCCAGCACGATCAAAACGATGCCCTGACCACCCCAACAAACTAAGAAACCCACACCCTGCCTTGGCGGGGCGTTTTGCTATGGAGCATTCGCATGACCGTTCGCACGATTGACGAGATTTTCCGCGATTTCGTGATTGATGTGTTCCGGCATCAGGGCCGTTTCATCCTTACAAGCCTGACCTTCGCGATACGTTGAAAGCGTTGCTTGAGGGCCTTTCGGCGTTCCCTGATAACCGCGTCATTCGTCTGAACAACGCTGACGAAGGTACAGAGCCAATAATATCGTCGTGACATCTTCTGTCGCGATCCCGACGGCTGCGTATCAGGTGCTTTATATCCTGAATGTCACTCAGGAGAACACGGGGCCGGTGACGGTATCTGGCACAATTAATCGCGATCTGGTTACGAATATCAATCAGCCAGTCCCGGCAGGATACCTGATGCCTGGCATGGCGCTGCTATGCATTGATACCGGCACAGAATTGCGTTTGCTGTCCTATGGCGATGCAGAAGCCATCCTTGCCGCCGCTGAAGACGCAGCCGCACGGGCGGAGGCGGCGGCATCCGGTGTTAATCTACCCAAAATCAGCGCCGCCGATGCAGGTAAGTCTCTTATCGTTAATCAAGATGGGACCGGTTATGATGTTGGCCTTGCTGTAGAGTTTGCCACCGAAACTCAAGCAAAAGCGCCGGGTACGCCAGAGAACGATGGGTTAGTCGTAAACCTTCTCCGAACTCTGCAACAAGGTCAGGCTCGCGGGTTTTTCTCGCTGAAAGACTTTGCGACTACAGTGATTGACAATGGAAGCAACAGTGCAATTTCTGCGTTGCAGTCTGCCGATAATTCAGGTGAAACAGTCGTAATGCCAAAGACAGACGACAGTTATCTGTTTGATGGAGACGTTATAATCAATAACCCTGTCAAGTTGCGTGGCGCATCTGGTGGCTCAAAAATAAAGCGCGTCGGTGCTATTGGTCGTTTTTTACTTAGAGCAAATCATATAAATATTGGAGATTTCATAGAAGATGGGTCTGAAATGACGGGGCAAGCAGCGTTGTTCCATTTCGACACTATCGAAAATGATGCATCCAGATACATTCAACATACGCTTATTGAGAATGTTCGGTCTTTTAATTCCGGTGGGTTGATTGACGATAACAATGTAAAGGGGGCCGCAGCCACACCTTATGTTTGGGACATTTTAATTAGGAACGTTTATGCCTTCGGATGCCGTGGGCGTGGCATCCGCATGAGGGATGGCTTTGCGTTTCTGCGCTTTGAAGATGTTGAAATTGGGTTAGGGCCGCAATATGGTGGTGTAAGCCTACCAGCATATGAGTTTCGAAATTTTGAGGGGTTATTTCTTCGCCGCACCGAAGCCACTGGATTGGATGGATATACAGACCTTGGATACGTCCCAGATGCTGAACAGCGGGGGTTCATCTTTGCAGACGGAGCAGCCCTCCACATCAATAGCCTGTTTGCAGATAATAACAAGGGTGATGGCGTGTTTTGCCAAAACGTCCAATACGTAGATGGAAACGATCTCAATTCATCCATCGACGGCGGAACTGGGTTCAATTTTATCAACGTAGATCGCATAAACATCAATACGATCCGCAGTGGTGGCCGCCGGAATATGGCACCAGGAAATCTTAACACTGTTTCCCAAGGTATCTCTTTGAATGCAAATTGTCAGACTGTAATTATAGGCAACGCAGTTACCCACAACTGGTGA

Protein sequences of DBSCAN-SWA_2

>NC_017244|958236:966575|961511_961745_+|WP_002969999.1|DBSCAN-SWA
MSVSSKNDVFRKFLFSYRYDGAKWSIEIQARSVDEARKRISSLALARYDGEVFARYPATVGFIPRMIAFFRNARLAA
>NC_017244|958236:966575|961860_962175_-|WP_004683740.1|DBSCAN-SWA
MGIKFSSKRPLTQEEEAEIQKMIASDPDAPEATDKQLAKAKPFKESFPDMAAKMEKAIRGRPRIDNPKTPVTIRLDQDVVQRFKATGKGWQGRMNDALRKAVGL
>NC_017244|958236:966575|959462_959939_+|WP_002966806.1|DBSCAN-SWA
MARTKAAKLQAKRSRGRPKKEGVLRAPSGQISRAKEPPAKVAQLARMRIFGMSASEALSDLAGDNLGRLHMAWKRDKAEGISTSQYDAAERYREVFNDKRKAECSAGAHYDHIGSIGASDPDEYEAWVKRAKQAYADARGAIDEAQAETRNSNLYAAV
>NC_017244|958236:966575|964019_964712_+|WP_006135935.1|DBSCAN-SWA
MQTRPRAKFYQQMTAIGAMTINEVRSLENYPPVGRDVMTTANTIRATFLDINQDYQASDADPWADEADVSERGEEAKDVQFNMAPSHSQARRLMKLEWFRANPNWVGTFNTNLMGLAAFGERLIGIQYPLFGINSVFEVLDFKFILGEGGILQGATIQVQSMTDTAYQWDTSQEGTAPVSDETTSDDDLPVPDAPDVLIIAGPAAELSFPPTGNILLNYMVRWKKTADTE
>NC_017244|958236:966575|961342_961513_-|WP_002964095.1|DBSCAN-SWA
MQYVLYRDNAGYWRWRLLANNHRTIADSGEGYVNRADAINGINLVKSSAAAPVVER
>NC_017244|958236:966575|959164_959440_+|WP_002964092.1|DBSCAN-SWA
MTPETALINEYLAKHGARRFEQGATSGIHGIASFMAEYGYEVAGAPKGGVKVRRGKGQWKRMSMPGLIAMADEIRLAQGLEPFSAAHKQAA
>NC_017244|958236:966575|960284_960995_+|WP_004683739.1|DBSCAN-SWA
MNIKSLLLASTVVLVAATGAKAADAVIEQEPAPVVVAPTFTWNGAYLGGQIGYGWGRSTLSDEDTSIRVKPDGFLGGLYAGYNFDMGNNFVLGVDGDITYNDLDASHSDTDPDLDLTTGVDSKLRWSGAVRARMGVAMDRWMPYIAGGVAFGNVKNSVSLTDGIESIGVSQSKTMTGWAAGAGVDYAATDNVIVRLEYRYTDYGHKDFSVVDGDLSVEARNKFKTHDIRLGVAYKF
>NC_017244|958236:966575|958236_958941_+|WP_005968944.1|DBSCAN-SWA
MRRFGCLSLVASLEDGRFTPLNFASRRFAYREERYRRNKASQVTQSDATEEIQKEGFPHTPSEENTPKEVQKKSPRSVLEAVLSQPIAVAVVEHRAKIKKPLTERGAELLAKRLAAAKDACGLTADQAADPMIERGWQGFDAEWAKNAMQSGWKPEAQRQASSYKPDSELSQEERDARWKKFMNYARNNRCWHSDVWGPMPNMLGCRVPAHLILPTDGRKSNGDPWTEQGRIAA
>NC_017244|958236:966575|962174_962420_-|WP_002966807.1|DBSCAN-SWA
MKIIWDEPKRQTNIAKHGLDFADLHFEFFLSAKVFPTKADRLMAIGEFNGLIIIAVIFKPVGSEALSVISMRSASQKERKL
>NC_017244|958236:966575|965123_966575_+|WP_006135932.1|DBSCAN-SWA
MTSSVAIPTAAYQVLYILNVTQENTGPVTVSGTINRDLVTNINQPVPAGYLMPGMALLCIDTGTELRLLSYGDAEAILAAAEDAAARAEAAASGVNLPKISAADAGKSLIVNQDGTGYDVGLAVEFATETQAKAPGTPENDGLVVNLLRTLQQGQARGFFSLKDFATTVIDNGSNSAISALQSADNSGETVVMPKTDDSYLFDGDVIINNPVKLRGASGGSKIKRVGAIGRFLLRANHINIGDFIEDGSEMTGQAALFHFDTIENDASRYIQHTLIENVRSFNSGGLIDDNNVKGAAATPYVWDILIRNVYAFGCRGRGIRMRDGFAFLRFEDVEIGLGPQYGGVSLPAYEFRNFEGLFLRRTEATGLDGYTDLGYVPDAEQRGFIFADGAALHINSLFADNNKGDGVFCQNVQYVDGNDLNSSIDGGTGFNFINVDRININTIRSGGRRNMAPGNLNTVSQGISLNANCQTVIIGNAVTHNW
>NC_017244|958236:966575|958937_959168_+|WP_002964091.1|DBSCAN-SWA
MIAAYHAKTDRSASYYWSKKDQEIFKPLRLFRQGKDTLEIAEIMGITEADALMRVHRAISSTKRKKVRTVPHGELA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005968944.1|958236_958941_+	hypothetical protein	A0A076GD06	Sinorhizobium_phage	4.5e-05	46.8
WP_002964091.1|958937_959168_+	hypothetical protein	NA	NA	NA	NA
WP_002964092.1|959164_959440_+	hypothetical protein	NA	NA	NA	NA
WP_002966806.1|959462_959939_+	hypothetical protein	NA	NA	NA	NA
WP_004683739.1|960284_960995_+	porin family protein	O11861	Bartonella_henselae_phage	5.1e-41	36.8
WP_002964095.1|961342_961513_-	DUF1508 domain-containing protein	A0A2P1N580	Mycobacterium_phage	3.1e-05	45.1
WP_002969999.1|961511_961745_+	hypothetical protein	NA	NA	NA	NA
WP_004683740.1|961860_962175_-	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	2.0e-05	42.1
WP_002966807.1|962174_962420_-	BrnT family toxin	NA	NA	NA	NA
WP_006135935.1|964019_964712_+	hypothetical protein	A0A141GEY5	Brucella_phage	4.4e-106	97.5
WP_006135932.1|965123_966575_+	hypothetical protein	A0A141GEY6	Brucella_phage	1.1e-135	56.9