CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015276	Marinomonas mediterranea MMB-1, complete sequence	10 crisprs	RT,cas2,cas1,PD-DExK,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,cmr1gr7,csa3,cas3,DEDDh,DinG,WYL,cas6f,cas7f,cas5f,cas8f,cas3f	0	43	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015276_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_1

693589-693695

TypeIII

Consensus_repeat	Method
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CRISPRCasFinder

1 spacers

cas2,cas1,PD-DExK,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,cmr1gr7

The CRISPR arrays of NC_015276_1

>merge|NC_015276|1|693589-693695|CRISPRCasFinder
TCGTCACACGTCTCAACGGCCAGCGGGTCGGAAACCTAAAGGAATGGCACTAATTGGCTATCGCCCAAAGTGTCTCAACGGCCTAAGCGGCCAGCGGATTTGAAGCA

>NC_015276|1|1|693589-693695|CRISPRCasFinder
TCGTCACACGTCTCAACGGCCAGCGGGTCGGAAAC	CTAAAGGAATGGCACTAATTGGCTATCGCCCAAAGT
GTCTCAACGGCCTAAGCGGCCAGCGGATTTGAAGCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013659852.1\|690062_690728_+\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|334855
NC_015276.1\|WP_013659853.1\|690727_691525_+\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|238817
NC_015276.1\|WP_013659849.1\|686563_687172_-\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|376738
NC_015276.1\|WP_013659851.1\|688919_689903_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226691
NC_015276.1\|WP_013659858.1\|698596_701470_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_015276.1\|WP_013659848.1\|685332_686550_-\|flagella-assembly-protein-FlgT	unknown	unknown	gnl\|CDD\|379855
NC_015276.1\|WP_013659866.1\|708522_709794_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|224286
NC_015276.1\|WP_013659854.1\|691686_692148_+\|DUF2489-domain-containing-protein	unknown	unknown	gnl\|CDD\|378470
NC_015276.1\|WP_013659865.1\|706612_708520_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_015276.1\|WP_013659850.1\|687620_688676_+\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NC_015276.1\|WP_041647744.1\|687257_687449_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013659855.1\|692155_692527_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013659861.1\|702959_704075_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|213662
NC_015276.1\|WP_013659863.1\|704493_705396_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_015276.1\|WP_013659856.1\|692601_693429_+\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|182386
NC_015276.1\|WP_013659864.1\|705395_706613_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|370625
NC_015276.1\|WP_083799838.1\|704071_704494_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_015276.1\|WP_013659857.1\|698321_698600_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015276.1\|WP_013659859.1\|701478_702249_-\|hypothetical-protein	PD-DExK	mkCas0090_PD-DExK_CAS-I:CAS-III	unknown
NC_015276.1\|WP_013659860.1\|702289_702859_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013659852.1\|690062_690728_+\|dienelactone-hydrolase-family-protein	gnl\|CDD\|334855	pfam02230, Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.	1.70803e-45
NC_015276.1\|WP_013659853.1\|690727_691525_+\|inositol-monophosphatase	gnl\|CDD\|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	2.04253e-87
NC_015276.1\|WP_013659849.1\|686563_687172_-\|LPP20-family-lipoprotein	gnl\|CDD\|376738	pfam02169, LPP20, LPP20 lipoprotein. This family contains the LPP20 lipoprotein, which is a non-essential class of lipoprotein.	5.57795e-13
NC_015276.1\|WP_013659851.1\|688919_689903_+\|hypothetical-protein	gnl\|CDD\|226691	COG4240, COG4240, Predicted kinase [General function prediction only].	2.84665e-50
NC_015276.1\|WP_013659858.1\|698596_701470_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.60253e-82
NC_015276.1\|WP_013659848.1\|685332_686550_-\|flagella-assembly-protein-FlgT	gnl\|CDD\|379855	pfam16539, FlgT_M, Flagellar assembly protein T, middle domain. FlgT_M is the middle region of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilize both ring structures. FlgT-N and FlgT-M are thought to be involved in the H-ring and the T-ring formation, respectively. and FlgT-M is also required for the stable association of FlgT with the basal body.	3.46655e-49
NC_015276.1\|WP_013659866.1\|708522_709794_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	5.29332e-33
NC_015276.1\|WP_013659854.1\|691686_692148_+\|DUF2489-domain-containing-protein	gnl\|CDD\|378470	pfam10675, DUF2489, Protein of unknown function (DUF2489). This is a bacterial family of uncharacterized proteins.	9.42447e-35
NC_015276.1\|WP_013659865.1\|706612_708520_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	4.16287e-49
NC_015276.1\|WP_013659850.1\|687620_688676_+\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NC_015276.1\|WP_013659861.1\|702959_704075_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	1.08344e-27
NC_015276.1\|WP_013659863.1\|704493_705396_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	5.37972e-62
NC_015276.1\|WP_013659856.1\|692601_693429_+\|mechanosensitive-ion-channel	gnl\|CDD\|182386	PRK10334, PRK10334, small-conductance mechanosensitive channel MscS.	4.58526e-87
NC_015276.1\|WP_013659864.1\|705395_706613_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|370625	pfam09700, Cas_Cmr3, CRISPR-associated protein (Cas_Cmr3). CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.	6.37989e-71
NC_015276.1\|WP_083799838.1\|704071_704494_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	8.58959e-35
NC_015276.1\|WP_013659857.1\|698321_698600_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.14213e-17

>NC_015276.1|WP_013659856.1|692601_693429_+|mechanosensitive-ion-channel
MNDLNDLLDQGSEWGPWLVDIAIGLAAGIVIFFVGRFLAKKIAKWCERRMLKSNVDKAVAGFTSSIVYALIFAASTLMALGQVGVQTTSFIAILGAAGLAIGLALQGSLSNFASGVLIILLRPFRAGDFIDAAGQMGVVDRIELFHTELKTPDNRVVIIPNSSIMGGSIVNFSREATRRLDLVIGISYESDIRLAKELLEGILNSEDRILKDPAYVIAVGELADSSVNFNVRPWVKSEDYWGVRADLLEKIKYTFDENGVGIPYPQMDVHVTKAD
>NC_015276.1|WP_013659855.1|692155_692527_+|hypothetical-protein
MFWQIFLSITVCFGLLSGLLIFFIRFKQRVPYYIIEHQKCIRLLDLAVKGRLLEHDWHVFIGMSIRTDEQVEALRKKCVVIDEAFCRGTRLYKGRQCVVFSEEGINQLSVLLDEWQHKANYQA
>NC_015276.1|WP_013659854.1|691686_692148_+|DUF2489-domain-containing-protein
MSTLSFVVALVVSVIVIIVSIGVILRQLKKNKLRKEKIAEGEKRLADERAKRVESIQVILQAVKNDENLTWIEASIRIKNLLDQLSLDLSEHETIKAFYAVEEETQHIPTHEQWRELPIKARMSFLKEMDDVEAKHKSTLEEARVALLAFPLE
>NC_015276.1|WP_013659853.1|690727_691525_+|inositol-monophosphatase
MTTLNEYLDFAKTLAKQAGLMMLEARKSSSFERNYKSDHELVTSVDLAIDQYLCSELASRYPKHKIFSEESTPDLLVDKANSAPVWVLDPIDGTVNFAHGLPHVAVSIGLFFDGKRQLGVIEAPFLQQTYWAVAGQGAYCNGERLSVSQQDVLRNSVVATGFPYQKAALGSLIPKVTRILENCQDIRRNGSAALDLCAVAHGLMDAYFESVKPWDMAAGAIIAEEAGATVGHFSEIRAEWPEPLNGDCLLVSTPKLYEPLRLLLK
>NC_015276.1|WP_013659852.1|690062_690728_+|dienelactone-hydrolase-family-protein
MAAPLEAIYVETNANPTYAVIWLHGLGADGNDFKGVVPSLGLGNSAVRFVFPHAPIRPVTINGGMPMRAWYDILEMDLDRKVDMSNIDESCEQISALVEEQIAQGIAAENIVIAGFSQGGVIAYQMALTSKYRFAGVMALSTYLADFESVPDANSVPNEETPFLIHHGSYDPVVEPTLGARAKAILTDKGFDTTYQSYPMPHSVCPAQIEDIASWLKGIVS
>NC_015276.1|WP_013659851.1|688919_689903_+|hypothetical-protein
MRTSSELKTELAKSMPGSLSQRLRFDVEQTLKSLYADESLADRIDDLFLPFSNWVSERSRPNVGPLILGMSGAQGCGKTTFCTVVSHILKKGFDLNAVVLSLDDLYLTRSDRMKYSQETHDLFSVRGVPGTHDVELADTIIQRLKELKDGEVMFLPVFDKSMDDRKPVHRWTQVEGPVDVVFFEGWCVGLGEMPRKTLQEPINELEATRDGDGEWRRLVNDHLKHGYRALFEHIDILLWMRAPNYEVVYEWRNKQERTLEDHLYDIHGGILDTLDIKVMSSDELKEFMQHYERLTRFMLSSMSGRADVVFTLNSAQKVIHWEVPIEH
>NC_015276.1|WP_013659850.1|687620_688676_+|DNA-polymerase-IV
MRKVIHIDADCFYAAVEMRDDPSLKDLPVAIGGPSNSRGVLATANYKAREFGVRSAMPSSLAKRLCPDLLIIPGNMSKYREASQQMHEIFRDYTDIIEPLSLDEAYLDVSNSTAFGGSATRIAQDIRKRIECSIGITVSAGVATNKFLAKVASDWNKPNGIKAVTPDELQSFVENIPVARISGVGKVAQEKLQRMGVVACRDLKAVPLEQLIKSFGSMAYRLLQFSQGIDDRPVQVSRERKSVSVEHTFAYDLNSVDESVVQLPNILEELKIRVKRNRCEQHICKYYLKLKFNDFTQTTIERPIVGKLEDSVFTALLIEAHARHNKPVRLIGAGYRLTPPILKQLELFPFH
>NC_015276.1|WP_041647744.1|687257_687449_-|hypothetical-protein
MRVFPVKIITSLVVGVFLSGCTYNHYYQNKTAMVPTPNSDTAMEQNATINKKPKQKLKIYRVH
>NC_015276.1|WP_013659849.1|686563_687172_-|LPP20-family-lipoprotein
MSVFKHLPLLAIISIALTACSGGPVLSPECTSVSPCNNSISNLTTGEEKDIEIIDVVPRDPIIVNATGYSAPISRKNLSKSQARLMSLRGSKLDAYRNLAERVYGLKIDGTSSISNMMTTHDELRTYVDAYLVGAKVVSQRELEDGTFETVVEMALQENFRQCVSSPSSILSNPACQVRPRYNTSSSSQSGNSATTSLYTVE
>NC_015276.1|WP_013659848.1|685332_686550_-|flagella-assembly-protein-FlgT
MWTSRNVFSTLLITLTVSVLSITSAFATTIQAQGDAIIYNNDVADARYRATEQAIKQATLQASSRLSVTESLTNGQSASQLRLQAAGKTQNTRILSESVEDNILSLVVEVDITPESMCDNGASNLYRKSVAITSFELQTPQQARLGALYNISRELPKSLAQEINRQGYLKALSATNISVYPDLINAPTSTNYDGSLTNITRLGEDLGVQYVISGVIRDIGEIYPKHPDQKTPLNNLLSWAKKEDQQRKMVLDLYVYDGFSGALIFEHHYDESGEWDTDESDKVRFGSGKFWTLNYGKVVAQILKGSAIDTSEQLRCQPFVANIFRTEGNLIHLSAGSLAGIKKGDQFRVYRRYEIYNQLQNTQTQLNNANINVTITQVQPNFAIGELSVDAKILNVQQQDVVIAW
>NC_015276.1|WP_013659857.1|698321_698600_-|CRISPR-associated-endonuclease-Cas2
MRIYLACFDIEDDKKRRKLSNLLLEYGDRVQYSVFEISLKDENELHKLRKKCSKYTEEADSLRFYWLNKESRKHSQDVWGNPIAVFPAAVLL
>NC_015276.1|WP_013659858.1|698596_701470_-|CRISPR-associated-endonuclease-Cas1
MLNSPLIDAVLPLRSVVITLRWLSPSKTGFLHHAGLHAWVRFLAGSPEQFSDFIVVEPIENGHISYQAGDGYRFRITVLNGGESLLDTLFSSLKRLPESAANHPDIAGAFSDNLVLEKIEDTFEHHQVTQIEDLSVFDINALMLETAVWSRQRRFKVAFNTPARLVKPKPEDGTELKGQNRYCRDKSDLNWQLFTHRLTDTFINLFQSRTGERLQRQNWPEAQLHAGLAVWLNNSYTNKKEKKVKDASGMLAQMQIEIDDDFPADLLALLVLGQYIGMGQNRAFGMGQYQLQDAYGYCSYPRPQAAKSLLEKSLSDASLHQACQTMYPRQANFDSSDTDEEHHDAIDELLTKLYVSRERIFKREFTPSQLHSVEIEKPEGGTRLLSVPNWHDRTLQKAVTECLGNTLEHIWMKHSYGYRKGHSRLQARDQINQYIQQGYEWVLESDIESFFDSVNWLNLEQRLKLLLPNEPLVPLLMQWVSAAKQTEDEQTLARHNGLPQGAPISPILANLLLDDLDQDMIAKGHQIVRYADDFVLLFKSKAAAESALDDIITALKEHHLAINLEKTRIVEASQGFRYLGYLFVDGYAIETKREYRKEHAQLDKQLNASSLENEPSLQQEPAVQNEQSTLIGEREKLGTLLIIAGDIAMLSSEKQRLIVEQYDELHTYPWATLSSVLLVGPHHITTPALKSAMFHNVPVHFASQYGRYQGVSAGAAPSVFGADFWLLQAQYLQQETNALNISQVLIQARIEGIRAVISRREKDAPELNKIQRLDEKRLRAETLDQLRGYEGQASKQLWAFFQRILEEDWGFTGRNRRPPKDPINALLSLGYTYLYSLVDSVNRTVGLYPWQGALHQRHGYHHTLASDLMEPWRYLVEHVVLTLINRHQIHKDDFVIKENGCEMSSGARKTLLKELLVQLTKVPKGGNSLLTEMSNQSYRLALSCKMQQRFIAWSPKR
>NC_015276.1|WP_013659859.1|701478_702249_-|hypothetical-protein
MNNAKTKSDTDGEQYLKDSFQREQELLESKLLFANQNITHNGERGEVNEKHFIEYLRSHLPKRYSVDSAIVVDSNGKTSNQIDIVVYDNQYTPTLFAQQDFCYVPAEAVYAVIEVKPEVNRDYIEYAQKQAYSVEALERTSIEITHAGGVYKPKPLFKIITGLIALKTGWQEGLASNSFKDAIQMPYTNQTRLDFVTSLQGGHFDCFEKGNEHYSQQNHLTFFLFRLLSQLQSLGTVPAVDWNKYANVLTEQSKPD
>NC_015276.1|WP_013659860.1|702289_702859_-|hypothetical-protein
MELLTKFWSLLSNYGNALNLIAIVISVIALSRSLSKSVPILYRLGKALSSHEILIYADDRYEDLKETLEDSGLFDPKKIKKVGINNLDKIRSADICIVHYQCAKNSIIKENDRLNLQEHQRDNTISRIINLKSNNNSLIVYAPHGERLQNEEFGLLDSKNNTALTNFRGRLVSDVLISMIAMKRQKALF
>NC_015276.1|WP_013659861.1|702959_704075_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MSSVQLVPQRLFNIYEMHLKSRTSNGLHSGLLLDKGYPASSTGVNTDKEAKARFIKSICGIKASELYTKEFNQWLRLTSKKSNSGKHTNNFEQLPLTLSNRLLIGLNGGGALETGCMINHHNGMPYIPGSSIKGAVRNFASRNLKDHESVWVQFFGNKPEDDLEDPFAGLITFHDAWWIPNSAPSENAGNFSNFPFIQDIVTTHHAEYYSKEGKSLATDFDDPIPNSLISVHGSFLFVIGGNENYLGVVKQMLEKTLKENGIGAKSTAGYGYFDEADESITKQFSILLSDTENTNTTPHSSELIREVSEIKLSKIPDIFGRNRNKTKNEKGKDYRSLCLLVCKHFGDEIANWATESGNKAKAYKELKEFLE
>NC_015276.1|WP_083799838.1|704071_704494_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MSVRQHKIAEAAYDCVNKRIEEGIDQKKYAALANKLPNLILQNGLAQATGFLMAKNESTNEHKKLLNDLAFVVNSGHLENQNTPNSDNGKELHQQIIQSDMTKFMQLTQQSLDASGALRRYVQGLMDTNKKDDDSQEETL
>NC_015276.1|WP_013659863.1|704493_705396_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MDLNIYHLHTHSALHCGTGQSAGIVDLPIARDKATHLPIVPGSSLRGVLRDKIRANEKDIEKALFGPRDIQSSEQSFAGALSLGDANLLVLPIRSLNGIVAYATCPFVLRNYANDTKISVKETPLPQPSAQQALVSNENVNVIQHDNHTELLVLEDLDISAEKDEKVQAWAKKIAEAVYSEQSDLKDEFINRFVVLSDNVFSYLSTTATELRTRIRITEKTGVVKEGALWSEENLPANAILWGVYSLSDSRDKKQELTAPELKEKLSASYTLQMGGNAGIGRGLVSLFTKKEEKETGGQE
>NC_015276.1|WP_013659864.1|705395_706613_-|type-III-B-CRISPR-module-associated-protein-Cmr3
MHTHDQKENTYLLDPKAPLIIRSGRPFDEQAGADDARFPPPSTMAGALRAAYARANNIGFNKENTQDILSKAIKGPLPVKQSTEEDIKTLLVPKPEDAQYYYDQAGNIEIVRLSPRELDENEGWDLPRRLLPVSYHDDQEKRHGKPAKGAQWWSLKDLLEWRLHKPINYKEVHKNGWIPPADDIRTHVAINPQSFAAEDGQLFQTSGLPMWQVKKENQSAFPDEKILLAGCINGDLFPEAHSKNDTPQSLNIGGERRLAEILTEDQLWPQPDEQILRDILEGEALSLTLLTPAIFKDGWLPCQQDENGHFIYRPPNTNTLELELVSAAIGRWTAQSGWDLAKHQPKPSRKLVPAGAVYWFRVREGNKHDLEQLWFSNISTKEQDRKDGFGLVLPHSTTLSASGAK
>NC_015276.1|WP_013659865.1|706612_708520_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MNTYLITIAIGPVQSLIEAARRTRDLWTGSWVLSECAKAAAKSLHDNQANLPNTGSSCLIFPSPESPETELLPSDFNDQYANISNVIRAEIQAEETDDIKVIAEQAKQAAKNRLTAIAESALNSAKGLPIRRDLWHNQIEHILEMFAVWVKVEDNQYQTASKKLNALLLARKASRHFENPEISEEHGSLLKSSLDGASESVVALEEKDKTTSEESNSIVSFKSGSIKRYKRKLGLANKEVLDALGVIKRLSGKAEQFTPYPRICADDWLNTLSNDQQESLSLHFDKLKNATDSDYGDACLVTDVKGNNNAYSDFPFDGELLYDFRLQNALQNTERDKSLSTSEQRVLGELQNSLRSINSNPVPYGVILKADGDNMGELFSQAQSATQSRAISQALHKFASSVRQLVQKHQGHAIYAGGDDVLAMLPLDQAIPCAEGLIDEFSNCMSSIIQEHHLDITKVPSLSVGLAIGHFMQPLGHLRARAVRAEKLAKGDHLPSDKKRNALSICLGLRSGPEVSWRCRWDDEETINALKTVMNAYSGNAQELSSRTGFAIRSVALQFAWSKTSSEIISPIQQAELKRLLDNLNKKGGEHKISKEMIALLTQQAEHIGLEALADLLIIARWLSAKAMSDLGAME
>NC_015276.1|WP_013659866.1|708522_709794_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MARTRLVDSSQLDALQSALSSLDQESQWQTYECTLITPMYGGGVEAGEVDKQMPIRASEIRGHLRFWWRLLYGTQDSKETFDREKAIWGGIAANPKDIKKSLVSIKVTTHAPIHLKPSTTYTDVKNGNTNKINKNSLGYAFGAASILTENEEDICWLSEGTRFTLYIKLDIPEPSHKNKEDIEEQINSSIKYWANFGGLGARTRRGFGSIYSSAFSIKSNTEIESLIKKLTNSKFALLQSKSASAVTAWETASQRLSSFRQIGIGRKSHKNRSTWPEPDQLRRFTDKNDNGKHKPEHKAGNVFPRAAFGMPILFKFKSSSDPQTLRLLPQGAERFASPLIIRPIQLQEGCVAIALLLPNWQQALTQELELQTEKDDTFLVANKEPPMSWGERNGAELASLITPMQGRADNPLEAFLDYFEKGR

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Crispr_ID: NC_015276_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_2

693937-698090

TypeIII

Consensus_repeat	Method
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CRISPRCasFinder
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACA	PILER-CR
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	PILER-CR
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACNNNNNNNNN	CRT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	PILER-CR
CGGCCAGCGGGTCTGAAAC	PILER-CR

58 spacers

cas2,cas1,PD-DExK,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,cmr1gr7

The CRISPR arrays of NC_015276_2

>merge|NC_015276|2|693937-698090|CRISPRCasFinder,PILER-CR,PILER-CR,CRT,PILER-CR,PILER-CR
TTGTTACACGCCTAAGCGGTCAGCGGGTCTGAAACAATAAAATAGTGTGACACGTCACAAACTGGAGAGGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAGAAAAAATCAACGAAGTAAAAGACTGTAAGCGGCGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATGCTATAAGCATTTCCTGCGGAGAGGGCGAATTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGTTAGTGAAGAAATATTTGTCTCAACGGCCTAAGCGGTCAGCGGGTCTGAAACTGACAATAAATAGGAGGATGTCTATGAAGACTACTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAAAAACCATGCTTAACAGCTCTCAGCAAAAGCGCCTAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATAGGCCGTTTAATGTCACAACATCTAATAAATTCGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAGAAGCTAAGGCTAAGACGGCTGAGACTAAGAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTGAAGACCCAGAAAAAAAACTCAAGCGGTTAATAGGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTTACAATGAATGGGATACTCCACTAAATGGAACAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTACGAAGATTTCGAGATTCAAACGGGCAACACAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATGACAAGTTCGATAAATTTCTAGAAGATAGCACGGTCTCAACGGCCAGCGGGTCTGAAACCTAACACACTAGAAGATATCAAGAAGCTAGAGAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTATGAAAACTATTACTTCTGCTACTAGCAGAAGGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACCGCAGTTGGCCTAGACTTCGGTCTTGCACTCAAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCAACAATAAGGAAGGTGATCTACGACAACACGGCGGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACCCCAACACCAAACGCGCTACAATTAGCTCTATGTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTGCAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTGCAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCTCTATTCCAGATCACATCCGTCTGCTCATGGTAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACCAAAAACATTATTAATTAATGACATCTGCGAAAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTTAAGTGGAAATGTGGCCGAATATCTCGGTATTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAAAGAAATGAGTTTTGAATTCGCTCTAGCAGAGGGTCTCAACGGCCTAAGTGGCCAGCGGGTCTGAAACCGTAATACTTGCGCGTTGCGTATCAGAGCTTAGCAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAACACAGAAAAAGCCAACGAGCAGATACTTGAAGCGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGATAATGAATTCGATTGCTACCTTAATTACAGGGGTAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGGGTACACAGTCTTCCAATCTTTCAGGAAAGAAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCTCGAAACCGGCTTCATAAAGTTCCCCATCGACATAACTCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTAATTCCTATGGCCGACGCACGCCTTAGCGAAACGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAATAAACAGCAAAAGCAAAATAAATCAATTAACAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGGTGATTTCGCACCAACCAACGCTACATTACCAGATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTTATTGAACTTCATTGGAAATCTTTCCATGAAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAGAACAAGTCAGTGTTACCGACGTCTCAGCAGAATGCCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCGGGAATCTGGGCTCCCGATGTGTACAAGCAAGGAGGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGCTGTAAGCAAAGACACCAGAGAGCTGGTTAATGTCTTCGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACACTTATCGCACTAGCGCTTACGACAATTTTTACAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCTGTAGAAAAACAATGGAATGACCTACAGTTTTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAACTGATTCGGCGCCTGAAACGGTGGAAGAGGCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTAAAATGATTAAAAAACAAGCTCTGAACCTATTTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGTGCTAGAACTTGAAGTTGAAGTTGAAAATGTGTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATATATTTTAAAGCACATGGGCGGAGAATTACCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAACGAAGGTGTTGTTTCGTTGGATGAACTTCCAGGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATAATGGTCTCACAAATCTCTGGAGCTGGTACTCTCAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAAGAAGAGTTCATAAACTCTATTACTTCTGCTAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGAAGGGAAAAAAACAAGCTAAGTATACAAAGTCTGAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGTGAAGTAGTTATTATCTGGAGCAAACGCTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAAAAAAACAGACATTTGGCTGTACATCGACACCGCTGCAAAGCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCTCTGTTTATTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCTCTGTTTATTTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTGAGCCTGTAGTGATCATGGAAGGAAATAGATTCTCTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAACCAACTAGAAGAAGAAACTAGTTATTACTTAAGGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAGGTTGTGAAGCCTTCTTTAAGCAACTATTTTGAGTCTCAACGGCCTAAGCGGCCAGTGGGTCTGAAACAGGCAAGGATGCCTCCCAAAAGGGGACAAGGAAGGTCTCAACGGCCAGCGGGTCTGAAACGCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAACGGCCAGCGGGTCTGAAACGCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAACGGCCAGCGGGTCTGAAAC

>NC_015276|2|2|693937-698090|CRISPRCasFinder
TTGTTACACGCCTAAGCGGTCAGCGGGTCTGAAAC	AATAAAATAGTGTGACACGTCACAAACTGGAGAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAAAAAATCAACGAAGTAAAAGACTGTAAGCGGC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGCTATAAGCATTTCCTGCGGAGAGGGCGAATTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGTTAG	TGAAGAAATATTTGTCTCAACGGCCTAAGCGGTCAGCGGGTCTGAAACTGACAATAAATAGGAGGATGTCTATGAAGACTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAACCATGCTTAACAGCTCTCAGCAAAAGCGCCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAGGCCGTTTAATGTCACAACATCTAATAAATTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAAGCTAAGGCTAAGACGGCTGAGACTAAGAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAAGACCCAGAAAAAAAACTCAAGCGGTTAATAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTACAATGAATGGGATACTCCACTAAATGGAACAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TACGAAGATTTCGAGATTCAAACGGGCAACACAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGACAAGTTCGATAAATTTCTAGAA
GATAGCACGGTCTCAACGGCCAGCGGGTCTGAAAC	CTAACACACTAGAAGATATCAAGAAGCTAGAGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTATGAAAACTATTACTTCTGCTACTAGCAGAAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CGCAGTTGGCCTAGACTTCGGTCTTGCACTCAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCAACAATAAGGAAGGTGATCTACGACAACACGGCG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CCCAACACCAAACGCGCTACAATTAGCTCTATGT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CAGCTGCAAAAATTAAAGCCTCATGAGCACAGAGAAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CAGCTGCAAAAATTAAAGCCTCATGAGCACAGAGAAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCTCTATTCCAGATCACATCCGTCTGCTCATGGTA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CAAAAACATTATTAATTAATGACATCTGCGAAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTAAGTGGAAATGTGGCCGAATATCTCGGTATTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAGAAATGAGTTTTGAATTCGCTCTAGCAGAGG
GTCTCAACGGCCTAAGTGGCCAGCGGGTCTGAAAC	CGTAATACTTGCGCGTTGCGTATCAGAGCTTAGCAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACACAGAAAAAGCCAACGAGCAGATACTTGAAGC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GATAATGAATTCGATTGCTACCTTAATTACAGGGGTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGGTACACAGTCTTCCAATCTTTCAGGAAAGAAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTCGAAACCGGCTTCATAAAGTTCCCCATCGACATAACTCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAATTCCTATGGCCGACGCACGCCTTAGCGAAAC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AATAAACAGCAAAAGCAAAATAAATCAATTAACAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGTGATTTCGCACCAACCAACGCTACATTACCAGAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTATTGAACTTCATTGGAAATCTTTCCATGAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAACAAGTCAGTGTTACCGACGTCTCAGCAGAAT
GCCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCGGGAATCTGGGCTCCCGATGTGTACAAGCAAGGAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GCTGTAAGCAAAGACACCAGAGAGCTGGTTAATGTCTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ACTTATCGCACTAGCGCTTACGACAATTTTTACA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGTAGAAAAACAATGGAATGACCTACAGTTTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACTGATTCGGCGCCTGAAACGGTGGAAGAGGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAAAATGATTAAAAAACAAGCTCTGAACCTATTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGCTAGAACTTGAAGTTGAAGTTGAAAATGTGTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATATATTTTAAAGCACATGGGCGGAGAATTACCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACGAAGGTGTTGTTTCGTTGGATGAACTTCCAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAATGGTCTCACAAATCTCTGGAGCTGGTACTCTCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAGAAGAGTTCATAAACTCTATTACTTCTGCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GAAGGGAAAAAAACAAGCTAAGTATACAAAGTCTGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGAAGTAGTTATTATCTGGAGCAAACGCTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAAAACAGACATTTGGCTGTACATCGACACCGCTGCAAAGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTAATAAAAAGTACTCTTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTTAATAAAAAGTACTCTTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAGCCTGTAGTGATCATGGAAGGAAATAGATTCTCTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACCAACTAGAAGAAGAAACTAGTTATTACTTAAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGGTTGTGAAGCCTTCTTTAAGCAACTATTTTGA
GTCTCAACGGCCTAAGCGGCCAGTGGGTCTGAAAC	AGGCAAGGATGCCTCCCAAAAGGGG
ACAAGGAAGGTCTCAACGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATG
TCTCATATGGTCTCAACGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATG
TCTCATATGGTCTCAACGGCCAGCGGGTCTGAAAC

>NC_015276|2|1|693946-694111|PILER-CR
GCCTAAGCGGTCAGCGGGTCTGAAACAATAAAATAGT	GTGACACGTCACAAACTGGAGAGGTCTCAACG
GCCTAAGCGGCCAGCGGGTCTGAAACAGAAAAAATCA	ACGAAGTAAAAGACTGTAAGCGGCGTCTCAACGG
CCTAAGCGGCCAGCGGGTCTGAAACATGCTATAAGCATTTCCTGCGGAGAGGGCGAATTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGTTAGTGAAGAAATATTTGTCTCAACGGCCTAAGCGGTCAGCGGGTCTGAAAC	TGACAATAAATAGGAGGATGTCTATGAAGACTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAACCATGCTTAACAGCTCTCAGCAAAAGCGCCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAGGCCGTTTAATGTCACAACATCTAATAAATTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAAGCTAAGGCTAAGACGGCTGAGACTAAGAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAAGACCCAGAAAAAAAACTCAAGCGGTTAATAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTACAATGAATGGGATACTCCACTAAATGGAACAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TACGAAGATTTCGAGATTCAAACGGGCAACACAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGACAAGTTCGATAAATTTCTAGAAGATAGC
ACGGTCTCAACGGCCAGCGGGTCTGAAACCTAACA	CACTAGAAGATATCAAGAAGCTAGAGAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTATGA	AAACTATTACTTCTGCTACTAGCAGAAGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCGCAGT	TGGCCTAGACTTCGGTCTTGCACTCAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCAAC	AATAAGGAAGGTGATCTACGACAACACGGCGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCCCAAC	ACCAAACGCGCTACAATTAGCTCTATGTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCTCT	ATTCCAGATCACATCCGTCTGCTCATGGTAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAAAAA	CATTATTAATTAATGACATCTGCGAAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTTAAG	TGGAAATGTGGCCGAATATCTCGGTATTTTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAAAGAA	ATGAGTTTTGAATTCGCTCTAGCAGAGGGTCTCA
ACGGCCTAAGTGGCCAGCGGGTCTGAAACCGTAAT	ACTTGCGCGTTGCGTATCAGAGCTTAGCAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAACACA	GAAAAAGCCAACGAGCAGATACTTGAAGCGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGATAAT	GAATTCGATTGCTACCTTAATTACAGGGGTAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGGGTACACAGTCTTCCAATCTTTCAGGAAAGAAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCTCGAAACCGGCTTCATAAAGTTCCCCATCGACATAACTCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAATTCCTATGGCCGACGCACGCCTTAGCGAAAC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AATAAACAGCAAAAGCAAAATAAATCAATTAACAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGTGATTTCGCACCAACCAACGCTACATTACCAGAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTATTGAACTTCATTGGAAATCTTTCCATGAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAACAAGTCAGTGTTACCGACGTCTCAGCAGAAT
GCCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCGGGAATCTGGGCTCCCGATGTGTACAAGCAAGGAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GCTGTAAGCAAAGACACCAGAGAGCTGGTTAATGTCTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ACTTATCGCACTAGCGCTTACGACAATTTTTACA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGTAGAAAAACAATGGAATGACCTACAGTTTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACTGATTCGGCGCCTGAAACGGTGGAAGAGGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAAAATGATTAAAAAACAAGCTCTGAACCTATTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGCTAGAACTTGAAGTTGAAGTTGAAAATGTGTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATATATTTTAAAGCACATGGGCGGAGAATTACCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACGAAGGTGTTGTTTCGTTGGATGAACTTCCAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAATGGTCTCACAAATCTCTGGAGCTGGTACTCTCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAGAAGAGTTCATAAACTCTATTACTTCTGCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GAAGGGAAAAAAACAAGCTAAGTATACAAAGTCTGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGTGAAGTAGTTATTATCTGGAGCAAACGCTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAAAACAGACATTTGGCTGTACATCGACACCGCTGCAAAGCTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TGAGCCTGTAGTGATCATGGAAGGAAATAGATTCTCTTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AACCAACTAGAAGAAGAAACTAGTTATTACTTAAGGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AGGTTGTGAAGCCTTCTTTAAGCAACTATTTTGAGTCTCAACGGCCTAAG
CGGCCAGTGGGTCTGAAAC	AGGCAAGGATGCCTCCCAAAAGGGGACAAGGAAGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA


>NC_015276|2|2|694195-695773|PILER-CR
	GTGACACGTCACAAACTGGAGAGGTCTCAACG
GCCTAAGCGGCCAGCGGGTCTGAAACAGAAAAAATCA	ACGAAGTAAAAGACTGTAAGCGGCGTCTCAACGG
CCTAAGCGGCCAGCGGGTCTGAAACATGCTATAAGCATTTCCTGCGGAGAGGGCGAATTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGTTAGTGAAGAAATATTTGTCTCAACGGCCTAAGCGGTCAGCGGGTCTGAAAC	TGACAATAAATAGGAGGATGTCTATGAAGACTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAACCATGCTTAACAGCTCTCAGCAAAAGCGCCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAGGCCGTTTAATGTCACAACATCTAATAAATTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAAGCTAAGGCTAAGACGGCTGAGACTAAGAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAAGACCCAGAAAAAAAACTCAAGCGGTTAATAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTACAATGAATGGGATACTCCACTAAATGGAACAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TACGAAGATTTCGAGATTCAAACGGGCAACACAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGACAAGTTCGATAAATTTCTAGAAGATAGC
ACGGTCTCAACGGCCAGCGGGTCTGAAACCTAACA	CACTAGAAGATATCAAGAAGCTAGAGAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTATGA	AAACTATTACTTCTGCTACTAGCAGAAGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCGCAGT	TGGCCTAGACTTCGGTCTTGCACTCAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCAAC	AATAAGGAAGGTGATCTACGACAACACGGCGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCCCAAC	ACCAAACGCGCTACAATTAGCTCTATGTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCTCT	ATTCCAGATCACATCCGTCTGCTCATGGTAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAAAAA	CATTATTAATTAATGACATCTGCGAAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTTAAG	TGGAAATGTGGCCGAATATCTCGGTATTTTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAAAGAA	ATGAGTTTTGAATTCGCTCTAGCAGAGGGTCTCA
ACGGCCTAAGTGGCCAGCGGGTCTGAAACCGTAAT	ACTTGCGCGTTGCGTATCAGAGCTTAGCAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAACACA	GAAAAAGCCAACGAGCAGATACTTGAAGCGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGATAAT	GAATTCGATTGCTACCTTAATTACAGGGGTAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGGGTACACAGTCTTCCAATCTTTCAGGAAAGAAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCTCGAAACCGGCTTCATAAAGTTCCCCATCGACATAACTCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAATTCCTATGGCCGACGCACGCCTTAGCGAAAC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AATAAACAGCAAAAGCAAAATAAATCAATTAACAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGTGATTTCGCACCAACCAACGCTACATTACCAGAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTATTGAACTTCATTGGAAATCTTTCCATGAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAACAAGTCAGTGTTACCGACGTCTCAGCAGAAT
GCCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCGGGAATCTGGGCTCCCGATGTGTACAAGCAAGGAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GCTGTAAGCAAAGACACCAGAGAGCTGGTTAATGTCTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ACTTATCGCACTAGCGCTTACGACAATTTTTACA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGTAGAAAAACAATGGAATGACCTACAGTTTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACTGATTCGGCGCCTGAAACGGTGGAAGAGGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAAAATGATTAAAAAACAAGCTCTGAACCTATTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGCTAGAACTTGAAGTTGAAGTTGAAAATGTGTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATATATTTTAAAGCACATGGGCGGAGAATTACCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACGAAGGTGTTGTTTCGTTGGATGAACTTCCAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAATGGTCTCACAAATCTCTGGAGCTGGTACTCTCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAGAAGAGTTCATAAACTCTATTACTTCTGCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GAAGGGAAAAAAACAAGCTAAGTATACAAAGTCTGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGTGAAGTAGTTATTATCTGGAGCAAACGCTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAAAACAGACATTTGGCTGTACATCGACACCGCTGCAAAGCTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TGAGCCTGTAGTGATCATGGAAGGAAATAGATTCTCTTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AACCAACTAGAAGAAGAAACTAGTTATTACTTAAGGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AGGTTGTGAAGCCTTCTTTAAGCAACTATTTTGAGTCTCAACGGCCTAAG
CGGCCAGTGGGTCTGAAAC	AGGCAAGGATGCCTCCCAAAAGGGGACAAGGAAGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA


>NC_015276|2|1|694195-697910|CRT
GTCTCAACGGCCTAAGCGGTCAGCGGGTCTGAAAC	TGACAATAAATAGGAGGATGTCTATGAAGACTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAACCATGCTTAACAGCTCTCAGCAAAAGCGCCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAGGCCGTTTAATGTCACAACATCTAATAAATTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAAGCTAAGGCTAAGACGGCTGAGACTAAGAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAAGACCCAGAAAAAAAACTCAAGCGGTTAATAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTACAATGAATGGGATACTCCACTAAATGGAACAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TACGAAGATTTCGAGATTCAAACGGGCAACACAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGACAAGTTCGATAAATTTCTAGAAGATAGCACG
GTCTCAACGGCCAGCGGGTCTGAAACCTAACACAC	TAGAAGATATCAAGAAGCTAGAGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTATGAAAACTATTACTTCTGCTACTAGCAGAAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CGCAGTTGGCCTAGACTTCGGTCTTGCACTCAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCAACAATAAGGAAGGTGATCTACGACAACACGGCG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CCCAACACCAAACGCGCTACAATTAGCTCTATGT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CAGCTGCAAAAATTAAAGCCTCATGAGCACAGAGAAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CAGCTGCAAAAATTAAAGCCTCATGAGCACAGAGAAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCTCTATTCCAGATCACATCCGTCTGCTCATGGTA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CAAAAACATTATTAATTAATGACATCTGCGAAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTAAGTGGAAATGTGGCCGAATATCTCGGTATTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAGAAATGAGTTTTGAATTCGCTCTAGCAGAGG
GTCTCAACGGCCTAAGTGGCCAGCGGGTCTGAAAC	CGTAATACTTGCGCGTTGCGTATCAGAGCTTAGCAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACACAGAAAAAGCCAACGAGCAGATACTTGAAGC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GATAATGAATTCGATTGCTACCTTAATTACAGGGGTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGGTACACAGTCTTCCAATCTTTCAGGAAAGAAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTCGAAACCGGCTTCATAAAGTTCCCCATCGACATAACTCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAATTCCTATGGCCGACGCACGCCTTAGCGAAAC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AATAAACAGCAAAAGCAAAATAAATCAATTAACAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGTGATTTCGCACCAACCAACGCTACATTACCAGAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTATTGAACTTCATTGGAAATCTTTCCATGAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAACAAGTCAGTGTTACCGACGTCTCAGCAGAAT
GCCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCGGGAATCTGGGCTCCCGATGTGTACAAGCAAGGAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GCTGTAAGCAAAGACACCAGAGAGCTGGTTAATGTCTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ACTTATCGCACTAGCGCTTACGACAATTTTTACA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGTAGAAAAACAATGGAATGACCTACAGTTTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACTGATTCGGCGCCTGAAACGGTGGAAGAGGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAAAATGATTAAAAAACAAGCTCTGAACCTATTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGCTAGAACTTGAAGTTGAAGTTGAAAATGTGTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATATATTTTAAAGCACATGGGCGGAGAATTACCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACGAAGGTGTTGTTTCGTTGGATGAACTTCCAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAATGGTCTCACAAATCTCTGGAGCTGGTACTCTCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAGAAGAGTTCATAAACTCTATTACTTCTGCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GAAGGGAAAAAAACAAGCTAAGTATACAAAGTCTGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGAAGTAGTTATTATCTGGAGCAAACGCTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAAAACAGACATTTGGCTGTACATCGACACCGCTGCAAAGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTAATAAAAAGTACTCTTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTTAATAAAAAGTACTCTTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAGCCTGTAGTGATCATGGAAGGAAATAGATTCTCTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACCAACTAGAAGAAGAAACTAGTTATTACTTAAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGGTTGTGAAGCCTTCTTTAAGCAACTATTTTGA
GTCTCAACGGCCTAAGCGGCCAGTGGGTCTGAAAC

>NC_015276|2|3|695886-697265|PILER-CR
	GTGACACGTCACAAACTGGAGAGGTCTCAACG
GCCTAAGCGGCCAGCGGGTCTGAAACAGAAAAAATCA	ACGAAGTAAAAGACTGTAAGCGGCGTCTCAACGG
CCTAAGCGGCCAGCGGGTCTGAAACATGCTATAAGCATTTCCTGCGGAGAGGGCGAATTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGTTAGTGAAGAAATATTTGTCTCAACGGCCTAAGCGGTCAGCGGGTCTGAAAC	TGACAATAAATAGGAGGATGTCTATGAAGACTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAACCATGCTTAACAGCTCTCAGCAAAAGCGCCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAGGCCGTTTAATGTCACAACATCTAATAAATTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAAGCTAAGGCTAAGACGGCTGAGACTAAGAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAAGACCCAGAAAAAAAACTCAAGCGGTTAATAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTACAATGAATGGGATACTCCACTAAATGGAACAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TACGAAGATTTCGAGATTCAAACGGGCAACACAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGACAAGTTCGATAAATTTCTAGAAGATAGC
ACGGTCTCAACGGCCAGCGGGTCTGAAACCTAACA	CACTAGAAGATATCAAGAAGCTAGAGAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTATGA	AAACTATTACTTCTGCTACTAGCAGAAGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCGCAGT	TGGCCTAGACTTCGGTCTTGCACTCAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCAAC	AATAAGGAAGGTGATCTACGACAACACGGCGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCCCAAC	ACCAAACGCGCTACAATTAGCTCTATGTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCTCT	ATTCCAGATCACATCCGTCTGCTCATGGTAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAAAAA	CATTATTAATTAATGACATCTGCGAAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTTAAG	TGGAAATGTGGCCGAATATCTCGGTATTTTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAAAGAA	ATGAGTTTTGAATTCGCTCTAGCAGAGGGTCTCA
ACGGCCTAAGTGGCCAGCGGGTCTGAAACCGTAAT	ACTTGCGCGTTGCGTATCAGAGCTTAGCAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAACACA	GAAAAAGCCAACGAGCAGATACTTGAAGCGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGATAAT	GAATTCGATTGCTACCTTAATTACAGGGGTAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGGGTACACAGTCTTCCAATCTTTCAGGAAAGAAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCTCGAAACCGGCTTCATAAAGTTCCCCATCGACATAACTCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAATTCCTATGGCCGACGCACGCCTTAGCGAAAC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AATAAACAGCAAAAGCAAAATAAATCAATTAACAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGTGATTTCGCACCAACCAACGCTACATTACCAGAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTATTGAACTTCATTGGAAATCTTTCCATGAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAACAAGTCAGTGTTACCGACGTCTCAGCAGAAT
GCCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCGGGAATCTGGGCTCCCGATGTGTACAAGCAAGGAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GCTGTAAGCAAAGACACCAGAGAGCTGGTTAATGTCTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ACTTATCGCACTAGCGCTTACGACAATTTTTACA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGTAGAAAAACAATGGAATGACCTACAGTTTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACTGATTCGGCGCCTGAAACGGTGGAAGAGGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAAAATGATTAAAAAACAAGCTCTGAACCTATTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGCTAGAACTTGAAGTTGAAGTTGAAAATGTGTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATATATTTTAAAGCACATGGGCGGAGAATTACCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACGAAGGTGTTGTTTCGTTGGATGAACTTCCAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAATGGTCTCACAAATCTCTGGAGCTGGTACTCTCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAGAAGAGTTCATAAACTCTATTACTTCTGCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GAAGGGAAAAAAACAAGCTAAGTATACAAAGTCTGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGTGAAGTAGTTATTATCTGGAGCAAACGCTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAAAACAGACATTTGGCTGTACATCGACACCGCTGCAAAGCTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TGAGCCTGTAGTGATCATGGAAGGAAATAGATTCTCTTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AACCAACTAGAAGAAGAAACTAGTTATTACTTAAGGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AGGTTGTGAAGCCTTCTTTAAGCAACTATTTTGAGTCTCAACGGCCTAAG
CGGCCAGTGGGTCTGAAAC	AGGCAAGGATGCCTCCCAAAAGGGGACAAGGAAGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA


>NC_015276|2|4|697314-698090|PILER-CR
	GTGACACGTCACAAACTGGAGAGGTCTCAACG
GCCTAAGCGGCCAGCGGGTCTGAAACAGAAAAAATCA	ACGAAGTAAAAGACTGTAAGCGGCGTCTCAACGG
CCTAAGCGGCCAGCGGGTCTGAAACATGCTATAAGCATTTCCTGCGGAGAGGGCGAATTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGTTAGTGAAGAAATATTTGTCTCAACGGCCTAAGCGGTCAGCGGGTCTGAAAC	TGACAATAAATAGGAGGATGTCTATGAAGACTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAACCATGCTTAACAGCTCTCAGCAAAAGCGCCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAGGCCGTTTAATGTCACAACATCTAATAAATTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAAGCTAAGGCTAAGACGGCTGAGACTAAGAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TGAAGACCCAGAAAAAAAACTCAAGCGGTTAATAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTACAATGAATGGGATACTCCACTAAATGGAACAAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TACGAAGATTTCGAGATTCAAACGGGCAACACAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGACAAGTTCGATAAATTTCTAGAAGATAGC
ACGGTCTCAACGGCCAGCGGGTCTGAAACCTAACA	CACTAGAAGATATCAAGAAGCTAGAGAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTATGA	AAACTATTACTTCTGCTACTAGCAGAAGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCGCAGT	TGGCCTAGACTTCGGTCTTGCACTCAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCAAC	AATAAGGAAGGTGATCTACGACAACACGGCGGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCCCAAC	ACCAAACGCGCTACAATTAGCTCTATGTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAGCTG	CAAAAATTAAAGCCTCATGAGCACAGAGAAATGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTCTCT	ATTCCAGATCACATCCGTCTGCTCATGGTAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACCAAAAA	CATTATTAATTAATGACATCTGCGAAAAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACTTTAAG	TGGAAATGTGGCCGAATATCTCGGTATTTTGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAAAGAA	ATGAGTTTTGAATTCGCTCTAGCAGAGGGTCTCA
ACGGCCTAAGTGGCCAGCGGGTCTGAAACCGTAAT	ACTTGCGCGTTGCGTATCAGAGCTTAGCAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACAACACA	GAAAAAGCCAACGAGCAGATACTTGAAGCGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGATAAT	GAATTCGATTGCTACCTTAATTACAGGGGTAAGTCTCA
ACGGCCTAAGCGGCCAGCGGGTCTGAAACGGGTACACAGTCTTCCAATCTTTCAGGAAAGAAATGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCTCGAAACCGGCTTCATAAAGTTCCCCATCGACATAACTCTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAATTCCTATGGCCGACGCACGCCTTAGCGAAAC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATGGGGCTGAAGACCCACTAGAAAAACTCAAGCTATTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AATAAACAGCAAAAGCAAAATAAATCAATTAACAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGTGATTTCGCACCAACCAACGCTACATTACCAGAT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TTTATTGAACTTCATTGGAAATCTTTCCATGAAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGAACAAGTCAGTGTTACCGACGTCTCAGCAGAAT
GCCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCGGGAATCTGGGCTCCCGATGTGTACAAGCAAGGAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GCTGTAAGCAAAGACACCAGAGAGCTGGTTAATGTCTTC
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ACTTATCGCACTAGCGCTTACGACAATTTTTACA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGTAGAAAAACAATGGAATGACCTACAGTTTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACTGATTCGGCGCCTGAAACGGTGGAAGAGGCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TAAAATGATTAAAAAACAAGCTCTGAACCTATTTTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GTGCTAGAACTTGAAGTTGAAGTTGAAAATGTGTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATATATTTTAAAGCACATGGGCGGAGAATTACCT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AACGAAGGTGTTGTTTCGTTGGATGAACTTCCAG
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATAATGGTCTCACAAATCTCTGGAGCTGGTACTCTCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAGAAGAGTTCATAAACTCTATTACTTCTGCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GAAGGGAAAAAAACAAGCTAAGTATACAAAGTCTGA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGTGAAGTAGTTATTATCTGGAGCAAACGCTTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AAAAAAACAGACATTTGGCTGTACATCGACACCGCTGCAAAGCTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	ATGGCGGAATTTTAATTAAGGTAACTAATACAAGCAAAGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TTCTCTGTTTATTTTTTTAATAAAAAGTACTCTTTCGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	TGAGCCTGTAGTGATCATGGAAGGAAATAGATTCTCTTGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AACCAACTAGAAGAAGAAACTAGTTATTACTTAAGGTCTCAACGGCCTAAG
CGGCCAGCGGGTCTGAAAC	AGGTTGTGAAGCCTTCTTTAAGCAACTATTTTGAGTCTCAACGGCCTAAG
CGGCCAGTGGGTCTGAAAC	AGGCAAGGATGCCTCCCAAAAGGGGACAAGGAAGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA
CGGCCAGCGGGTCTGAAAC	GCAGAAGACATTAATTGGGATAATGTCTCATATGGTCTCAA
CGGCCAGCGGGTCTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013659852.1\|690062_690728_+\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|334855
NC_015276.1\|WP_013659853.1\|690727_691525_+\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|238817
NC_015276.1\|WP_013659849.1\|686563_687172_-\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|376738
NC_015276.1\|WP_013659851.1\|688919_689903_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226691
NC_015276.1\|WP_013659858.1\|698596_701470_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_015276.1\|WP_013659848.1\|685332_686550_-\|flagella-assembly-protein-FlgT	unknown	unknown	gnl\|CDD\|379855
NC_015276.1\|WP_013659866.1\|708522_709794_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|224286
NC_015276.1\|WP_013659854.1\|691686_692148_+\|DUF2489-domain-containing-protein	unknown	unknown	gnl\|CDD\|378470
NC_015276.1\|WP_013659865.1\|706612_708520_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_015276.1\|WP_013659850.1\|687620_688676_+\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NC_015276.1\|WP_041647744.1\|687257_687449_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013659855.1\|692155_692527_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013659861.1\|702959_704075_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|213662
NC_015276.1\|WP_013659863.1\|704493_705396_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_015276.1\|WP_013659856.1\|692601_693429_+\|mechanosensitive-ion-channel	unknown	unknown	gnl\|CDD\|182386
NC_015276.1\|WP_013659864.1\|705395_706613_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|370625
NC_015276.1\|WP_083799838.1\|704071_704494_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_015276.1\|WP_013659857.1\|698321_698600_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015276.1\|WP_013659859.1\|701478_702249_-\|hypothetical-protein	PD-DExK	mkCas0090_PD-DExK_CAS-I:CAS-III	unknown
NC_015276.1\|WP_013659860.1\|702289_702859_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013659852.1\|690062_690728_+\|dienelactone-hydrolase-family-protein	gnl\|CDD\|334855	pfam02230, Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.	1.70803e-45
NC_015276.1\|WP_013659853.1\|690727_691525_+\|inositol-monophosphatase	gnl\|CDD\|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	2.04253e-87
NC_015276.1\|WP_013659849.1\|686563_687172_-\|LPP20-family-lipoprotein	gnl\|CDD\|376738	pfam02169, LPP20, LPP20 lipoprotein. This family contains the LPP20 lipoprotein, which is a non-essential class of lipoprotein.	5.57795e-13
NC_015276.1\|WP_013659851.1\|688919_689903_+\|hypothetical-protein	gnl\|CDD\|226691	COG4240, COG4240, Predicted kinase [General function prediction only].	2.84665e-50
NC_015276.1\|WP_013659858.1\|698596_701470_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.60253e-82
NC_015276.1\|WP_013659848.1\|685332_686550_-\|flagella-assembly-protein-FlgT	gnl\|CDD\|379855	pfam16539, FlgT_M, Flagellar assembly protein T, middle domain. FlgT_M is the middle region of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilize both ring structures. FlgT-N and FlgT-M are thought to be involved in the H-ring and the T-ring formation, respectively. and FlgT-M is also required for the stable association of FlgT with the basal body.	3.46655e-49
NC_015276.1\|WP_013659866.1\|708522_709794_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	5.29332e-33
NC_015276.1\|WP_013659854.1\|691686_692148_+\|DUF2489-domain-containing-protein	gnl\|CDD\|378470	pfam10675, DUF2489, Protein of unknown function (DUF2489). This is a bacterial family of uncharacterized proteins.	9.42447e-35
NC_015276.1\|WP_013659865.1\|706612_708520_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	4.16287e-49
NC_015276.1\|WP_013659850.1\|687620_688676_+\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NC_015276.1\|WP_013659861.1\|702959_704075_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	1.08344e-27
NC_015276.1\|WP_013659863.1\|704493_705396_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	5.37972e-62
NC_015276.1\|WP_013659856.1\|692601_693429_+\|mechanosensitive-ion-channel	gnl\|CDD\|182386	PRK10334, PRK10334, small-conductance mechanosensitive channel MscS.	4.58526e-87
NC_015276.1\|WP_013659864.1\|705395_706613_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|370625	pfam09700, Cas_Cmr3, CRISPR-associated protein (Cas_Cmr3). CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.	6.37989e-71
NC_015276.1\|WP_083799838.1\|704071_704494_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	8.58959e-35
NC_015276.1\|WP_013659857.1\|698321_698600_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.14213e-17

>NC_015276.1|WP_013659856.1|692601_693429_+|mechanosensitive-ion-channel
MNDLNDLLDQGSEWGPWLVDIAIGLAAGIVIFFVGRFLAKKIAKWCERRMLKSNVDKAVAGFTSSIVYALIFAASTLMALGQVGVQTTSFIAILGAAGLAIGLALQGSLSNFASGVLIILLRPFRAGDFIDAAGQMGVVDRIELFHTELKTPDNRVVIIPNSSIMGGSIVNFSREATRRLDLVIGISYESDIRLAKELLEGILNSEDRILKDPAYVIAVGELADSSVNFNVRPWVKSEDYWGVRADLLEKIKYTFDENGVGIPYPQMDVHVTKAD
>NC_015276.1|WP_013659855.1|692155_692527_+|hypothetical-protein
MFWQIFLSITVCFGLLSGLLIFFIRFKQRVPYYIIEHQKCIRLLDLAVKGRLLEHDWHVFIGMSIRTDEQVEALRKKCVVIDEAFCRGTRLYKGRQCVVFSEEGINQLSVLLDEWQHKANYQA
>NC_015276.1|WP_013659854.1|691686_692148_+|DUF2489-domain-containing-protein
MSTLSFVVALVVSVIVIIVSIGVILRQLKKNKLRKEKIAEGEKRLADERAKRVESIQVILQAVKNDENLTWIEASIRIKNLLDQLSLDLSEHETIKAFYAVEEETQHIPTHEQWRELPIKARMSFLKEMDDVEAKHKSTLEEARVALLAFPLE
>NC_015276.1|WP_013659853.1|690727_691525_+|inositol-monophosphatase
MTTLNEYLDFAKTLAKQAGLMMLEARKSSSFERNYKSDHELVTSVDLAIDQYLCSELASRYPKHKIFSEESTPDLLVDKANSAPVWVLDPIDGTVNFAHGLPHVAVSIGLFFDGKRQLGVIEAPFLQQTYWAVAGQGAYCNGERLSVSQQDVLRNSVVATGFPYQKAALGSLIPKVTRILENCQDIRRNGSAALDLCAVAHGLMDAYFESVKPWDMAAGAIIAEEAGATVGHFSEIRAEWPEPLNGDCLLVSTPKLYEPLRLLLK
>NC_015276.1|WP_013659852.1|690062_690728_+|dienelactone-hydrolase-family-protein
MAAPLEAIYVETNANPTYAVIWLHGLGADGNDFKGVVPSLGLGNSAVRFVFPHAPIRPVTINGGMPMRAWYDILEMDLDRKVDMSNIDESCEQISALVEEQIAQGIAAENIVIAGFSQGGVIAYQMALTSKYRFAGVMALSTYLADFESVPDANSVPNEETPFLIHHGSYDPVVEPTLGARAKAILTDKGFDTTYQSYPMPHSVCPAQIEDIASWLKGIVS
>NC_015276.1|WP_013659851.1|688919_689903_+|hypothetical-protein
MRTSSELKTELAKSMPGSLSQRLRFDVEQTLKSLYADESLADRIDDLFLPFSNWVSERSRPNVGPLILGMSGAQGCGKTTFCTVVSHILKKGFDLNAVVLSLDDLYLTRSDRMKYSQETHDLFSVRGVPGTHDVELADTIIQRLKELKDGEVMFLPVFDKSMDDRKPVHRWTQVEGPVDVVFFEGWCVGLGEMPRKTLQEPINELEATRDGDGEWRRLVNDHLKHGYRALFEHIDILLWMRAPNYEVVYEWRNKQERTLEDHLYDIHGGILDTLDIKVMSSDELKEFMQHYERLTRFMLSSMSGRADVVFTLNSAQKVIHWEVPIEH
>NC_015276.1|WP_013659850.1|687620_688676_+|DNA-polymerase-IV
MRKVIHIDADCFYAAVEMRDDPSLKDLPVAIGGPSNSRGVLATANYKAREFGVRSAMPSSLAKRLCPDLLIIPGNMSKYREASQQMHEIFRDYTDIIEPLSLDEAYLDVSNSTAFGGSATRIAQDIRKRIECSIGITVSAGVATNKFLAKVASDWNKPNGIKAVTPDELQSFVENIPVARISGVGKVAQEKLQRMGVVACRDLKAVPLEQLIKSFGSMAYRLLQFSQGIDDRPVQVSRERKSVSVEHTFAYDLNSVDESVVQLPNILEELKIRVKRNRCEQHICKYYLKLKFNDFTQTTIERPIVGKLEDSVFTALLIEAHARHNKPVRLIGAGYRLTPPILKQLELFPFH
>NC_015276.1|WP_041647744.1|687257_687449_-|hypothetical-protein
MRVFPVKIITSLVVGVFLSGCTYNHYYQNKTAMVPTPNSDTAMEQNATINKKPKQKLKIYRVH
>NC_015276.1|WP_013659849.1|686563_687172_-|LPP20-family-lipoprotein
MSVFKHLPLLAIISIALTACSGGPVLSPECTSVSPCNNSISNLTTGEEKDIEIIDVVPRDPIIVNATGYSAPISRKNLSKSQARLMSLRGSKLDAYRNLAERVYGLKIDGTSSISNMMTTHDELRTYVDAYLVGAKVVSQRELEDGTFETVVEMALQENFRQCVSSPSSILSNPACQVRPRYNTSSSSQSGNSATTSLYTVE
>NC_015276.1|WP_013659848.1|685332_686550_-|flagella-assembly-protein-FlgT
MWTSRNVFSTLLITLTVSVLSITSAFATTIQAQGDAIIYNNDVADARYRATEQAIKQATLQASSRLSVTESLTNGQSASQLRLQAAGKTQNTRILSESVEDNILSLVVEVDITPESMCDNGASNLYRKSVAITSFELQTPQQARLGALYNISRELPKSLAQEINRQGYLKALSATNISVYPDLINAPTSTNYDGSLTNITRLGEDLGVQYVISGVIRDIGEIYPKHPDQKTPLNNLLSWAKKEDQQRKMVLDLYVYDGFSGALIFEHHYDESGEWDTDESDKVRFGSGKFWTLNYGKVVAQILKGSAIDTSEQLRCQPFVANIFRTEGNLIHLSAGSLAGIKKGDQFRVYRRYEIYNQLQNTQTQLNNANINVTITQVQPNFAIGELSVDAKILNVQQQDVVIAW
>NC_015276.1|WP_013659857.1|698321_698600_-|CRISPR-associated-endonuclease-Cas2
MRIYLACFDIEDDKKRRKLSNLLLEYGDRVQYSVFEISLKDENELHKLRKKCSKYTEEADSLRFYWLNKESRKHSQDVWGNPIAVFPAAVLL
>NC_015276.1|WP_013659858.1|698596_701470_-|CRISPR-associated-endonuclease-Cas1
MLNSPLIDAVLPLRSVVITLRWLSPSKTGFLHHAGLHAWVRFLAGSPEQFSDFIVVEPIENGHISYQAGDGYRFRITVLNGGESLLDTLFSSLKRLPESAANHPDIAGAFSDNLVLEKIEDTFEHHQVTQIEDLSVFDINALMLETAVWSRQRRFKVAFNTPARLVKPKPEDGTELKGQNRYCRDKSDLNWQLFTHRLTDTFINLFQSRTGERLQRQNWPEAQLHAGLAVWLNNSYTNKKEKKVKDASGMLAQMQIEIDDDFPADLLALLVLGQYIGMGQNRAFGMGQYQLQDAYGYCSYPRPQAAKSLLEKSLSDASLHQACQTMYPRQANFDSSDTDEEHHDAIDELLTKLYVSRERIFKREFTPSQLHSVEIEKPEGGTRLLSVPNWHDRTLQKAVTECLGNTLEHIWMKHSYGYRKGHSRLQARDQINQYIQQGYEWVLESDIESFFDSVNWLNLEQRLKLLLPNEPLVPLLMQWVSAAKQTEDEQTLARHNGLPQGAPISPILANLLLDDLDQDMIAKGHQIVRYADDFVLLFKSKAAAESALDDIITALKEHHLAINLEKTRIVEASQGFRYLGYLFVDGYAIETKREYRKEHAQLDKQLNASSLENEPSLQQEPAVQNEQSTLIGEREKLGTLLIIAGDIAMLSSEKQRLIVEQYDELHTYPWATLSSVLLVGPHHITTPALKSAMFHNVPVHFASQYGRYQGVSAGAAPSVFGADFWLLQAQYLQQETNALNISQVLIQARIEGIRAVISRREKDAPELNKIQRLDEKRLRAETLDQLRGYEGQASKQLWAFFQRILEEDWGFTGRNRRPPKDPINALLSLGYTYLYSLVDSVNRTVGLYPWQGALHQRHGYHHTLASDLMEPWRYLVEHVVLTLINRHQIHKDDFVIKENGCEMSSGARKTLLKELLVQLTKVPKGGNSLLTEMSNQSYRLALSCKMQQRFIAWSPKR
>NC_015276.1|WP_013659859.1|701478_702249_-|hypothetical-protein
MNNAKTKSDTDGEQYLKDSFQREQELLESKLLFANQNITHNGERGEVNEKHFIEYLRSHLPKRYSVDSAIVVDSNGKTSNQIDIVVYDNQYTPTLFAQQDFCYVPAEAVYAVIEVKPEVNRDYIEYAQKQAYSVEALERTSIEITHAGGVYKPKPLFKIITGLIALKTGWQEGLASNSFKDAIQMPYTNQTRLDFVTSLQGGHFDCFEKGNEHYSQQNHLTFFLFRLLSQLQSLGTVPAVDWNKYANVLTEQSKPD
>NC_015276.1|WP_013659860.1|702289_702859_-|hypothetical-protein
MELLTKFWSLLSNYGNALNLIAIVISVIALSRSLSKSVPILYRLGKALSSHEILIYADDRYEDLKETLEDSGLFDPKKIKKVGINNLDKIRSADICIVHYQCAKNSIIKENDRLNLQEHQRDNTISRIINLKSNNNSLIVYAPHGERLQNEEFGLLDSKNNTALTNFRGRLVSDVLISMIAMKRQKALF
>NC_015276.1|WP_013659861.1|702959_704075_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MSSVQLVPQRLFNIYEMHLKSRTSNGLHSGLLLDKGYPASSTGVNTDKEAKARFIKSICGIKASELYTKEFNQWLRLTSKKSNSGKHTNNFEQLPLTLSNRLLIGLNGGGALETGCMINHHNGMPYIPGSSIKGAVRNFASRNLKDHESVWVQFFGNKPEDDLEDPFAGLITFHDAWWIPNSAPSENAGNFSNFPFIQDIVTTHHAEYYSKEGKSLATDFDDPIPNSLISVHGSFLFVIGGNENYLGVVKQMLEKTLKENGIGAKSTAGYGYFDEADESITKQFSILLSDTENTNTTPHSSELIREVSEIKLSKIPDIFGRNRNKTKNEKGKDYRSLCLLVCKHFGDEIANWATESGNKAKAYKELKEFLE
>NC_015276.1|WP_083799838.1|704071_704494_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MSVRQHKIAEAAYDCVNKRIEEGIDQKKYAALANKLPNLILQNGLAQATGFLMAKNESTNEHKKLLNDLAFVVNSGHLENQNTPNSDNGKELHQQIIQSDMTKFMQLTQQSLDASGALRRYVQGLMDTNKKDDDSQEETL
>NC_015276.1|WP_013659863.1|704493_705396_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MDLNIYHLHTHSALHCGTGQSAGIVDLPIARDKATHLPIVPGSSLRGVLRDKIRANEKDIEKALFGPRDIQSSEQSFAGALSLGDANLLVLPIRSLNGIVAYATCPFVLRNYANDTKISVKETPLPQPSAQQALVSNENVNVIQHDNHTELLVLEDLDISAEKDEKVQAWAKKIAEAVYSEQSDLKDEFINRFVVLSDNVFSYLSTTATELRTRIRITEKTGVVKEGALWSEENLPANAILWGVYSLSDSRDKKQELTAPELKEKLSASYTLQMGGNAGIGRGLVSLFTKKEEKETGGQE
>NC_015276.1|WP_013659864.1|705395_706613_-|type-III-B-CRISPR-module-associated-protein-Cmr3
MHTHDQKENTYLLDPKAPLIIRSGRPFDEQAGADDARFPPPSTMAGALRAAYARANNIGFNKENTQDILSKAIKGPLPVKQSTEEDIKTLLVPKPEDAQYYYDQAGNIEIVRLSPRELDENEGWDLPRRLLPVSYHDDQEKRHGKPAKGAQWWSLKDLLEWRLHKPINYKEVHKNGWIPPADDIRTHVAINPQSFAAEDGQLFQTSGLPMWQVKKENQSAFPDEKILLAGCINGDLFPEAHSKNDTPQSLNIGGERRLAEILTEDQLWPQPDEQILRDILEGEALSLTLLTPAIFKDGWLPCQQDENGHFIYRPPNTNTLELELVSAAIGRWTAQSGWDLAKHQPKPSRKLVPAGAVYWFRVREGNKHDLEQLWFSNISTKEQDRKDGFGLVLPHSTTLSASGAK
>NC_015276.1|WP_013659865.1|706612_708520_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MNTYLITIAIGPVQSLIEAARRTRDLWTGSWVLSECAKAAAKSLHDNQANLPNTGSSCLIFPSPESPETELLPSDFNDQYANISNVIRAEIQAEETDDIKVIAEQAKQAAKNRLTAIAESALNSAKGLPIRRDLWHNQIEHILEMFAVWVKVEDNQYQTASKKLNALLLARKASRHFENPEISEEHGSLLKSSLDGASESVVALEEKDKTTSEESNSIVSFKSGSIKRYKRKLGLANKEVLDALGVIKRLSGKAEQFTPYPRICADDWLNTLSNDQQESLSLHFDKLKNATDSDYGDACLVTDVKGNNNAYSDFPFDGELLYDFRLQNALQNTERDKSLSTSEQRVLGELQNSLRSINSNPVPYGVILKADGDNMGELFSQAQSATQSRAISQALHKFASSVRQLVQKHQGHAIYAGGDDVLAMLPLDQAIPCAEGLIDEFSNCMSSIIQEHHLDITKVPSLSVGLAIGHFMQPLGHLRARAVRAEKLAKGDHLPSDKKRNALSICLGLRSGPEVSWRCRWDDEETINALKTVMNAYSGNAQELSSRTGFAIRSVALQFAWSKTSSEIISPIQQAELKRLLDNLNKKGGEHKISKEMIALLTQQAEHIGLEALADLLIIARWLSAKAMSDLGAME
>NC_015276.1|WP_013659866.1|708522_709794_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MARTRLVDSSQLDALQSALSSLDQESQWQTYECTLITPMYGGGVEAGEVDKQMPIRASEIRGHLRFWWRLLYGTQDSKETFDREKAIWGGIAANPKDIKKSLVSIKVTTHAPIHLKPSTTYTDVKNGNTNKINKNSLGYAFGAASILTENEEDICWLSEGTRFTLYIKLDIPEPSHKNKEDIEEQINSSIKYWANFGGLGARTRRGFGSIYSSAFSIKSNTEIESLIKKLTNSKFALLQSKSASAVTAWETASQRLSSFRQIGIGRKSHKNRSTWPEPDQLRRFTDKNDNGKHKPEHKAGNVFPRAAFGMPILFKFKSSSDPQTLRLLPQGAERFASPLIIRPIQLQEGCVAIALLLPNWQQALTQELELQTEKDDTFLVANKEPPMSWGERNGAELASLITPMQGRADNPLEAFLDYFEKGR

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Crispr_ID: NC_015276_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_3

710346-710944

TypeIII

Consensus_repeat	Method
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CRISPRCasFinder
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACNNNNNNNNN	CRT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	PILER-CR

8 spacers

cmr1gr7,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,PD-DExK,cas1,cas2

The CRISPR arrays of NC_015276_3

>merge|NC_015276|3|710346-710944|CRISPRCasFinder,CRT,PILER-CR
TCGTCACACGTCTCAACGACCAGCGGGTCTGAAACAGAACGCACTTGTGCGCGCAGGTTTATGCGTCAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGACTTAATCCATCTGACGTGTTCTCAACTTCTATCTAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACCTATCGTATAGCTGAAGACTTGAGCAAGTATTACTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACAGCTTGATGAGGAGATGATGGCAATACCGCCAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATTCTGCTCCCATGCCTCCCAGTCTTCGTTCAGTAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACATTGATAATTTCCGCCATAACGAAGATAATATCTTGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACTCTGAATACTAACGAAAAATAGAAACCCCAACCCCCAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAACGGGGAATTGGTTTGCGTGGCGGAGATCTTTAAAGTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC

>NC_015276|3|3|710346-710944|CRISPRCasFinder
TCGTCACACGTCTCAACGACCAGCGGGTCTGAAAC	AGAACGCACTTGTGCGCGCAGGTTTATGCGTCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GACTTAATCCATCTGACGTGTTCTCAACTTCTATCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CTATCGTATAGCTGAAGACTTGAGCAAGTATTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGCTTGATGAGGAGATGATGGCAATACCGCCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATTCTGCTCCCATGCCTCCCAGTCTTCGTTCAGTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATTGATAATTTCCGCCATAACGAAGATAATATCTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGAATACTAACGAAAAATAGAAACCCCAACCCCCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGGGAATTGGTTTGCGTGGCGGAGATCTTTAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC

>NC_015276|3|2|710355-710944|CRT
GTCTCAACGACCAGCGGGTCTGAAACAGAACGCAC	TTGTGCGCGCAGGTTTATGCGTCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GACTTAATCCATCTGACGTGTTCTCAACTTCTATCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CTATCGTATAGCTGAAGACTTGAGCAAGTATTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGCTTGATGAGGAGATGATGGCAATACCGCCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATTCTGCTCCCATGCCTCCCAGTCTTCGTTCAGTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATTGATAATTTCCGCCATAACGAAGATAATATCTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGAATACTAACGAAAAATAGAAACCCCAACCCCCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGGGAATTGGTTTGCGTGGCGGAGATCTTTAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC

>NC_015276|3|5|710416-710944|PILER-CR
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GACTTAATCCATCTGACGTGTTCTCAACTTCTATCTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	CTATCGTATAGCTGAAGACTTGAGCAAGTATTACTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	AGCTTGATGAGGAGATGATGGCAATACCGCCAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATTCTGCTCCCATGCCTCCCAGTCTTCGTTCAGTAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	ATTGATAATTTCCGCCATAACGAAGATAATATCTT
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	TCTGAATACTAACGAAAAATAGAAACCCCAACCCCCA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC	GGGGAATTGGTTTGCGTGGCGGAGATCTTTAAA
GTCTCAACGGCCTAAGCGGCCAGCGGGTCTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013659866.1\|708522_709794_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|224286
NC_015276.1\|WP_013659858.1\|698596_701470_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_015276.1\|WP_013659874.1\|718553_718802_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|234588
NC_015276.1\|WP_013659870.1\|714069_714615_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239948
NC_015276.1\|WP_013659865.1\|706612_708520_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_015276.1\|WP_013659871.1\|714640_715897_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|226911
NC_015276.1\|WP_013659868.1\|712687_713572_+\|DUF72-domain-containing-protein	unknown	unknown	gnl\|CDD\|182366
NC_015276.1\|WP_013659861.1\|702959_704075_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|213662
NC_015276.1\|WP_013659863.1\|704493_705396_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_015276.1\|WP_013659875.1\|718818_719364_+\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NC_015276.1\|WP_013659872.1\|716014_716782_-\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|226621
NC_015276.1\|WP_041647746.1\|712187_712691_+\|transcription-elongation-factor-GreB	unknown	unknown	gnl\|CDD\|179345
NC_015276.1\|WP_083799838.1\|704071_704494_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_015276.1\|WP_013659869.1\|713662_713974_+\|NIF3-1	unknown	unknown	gnl\|CDD\|225860
NC_015276.1\|WP_013659864.1\|705395_706613_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|370625
NC_015276.1\|WP_013659857.1\|698321_698600_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015276.1\|WP_013659859.1\|701478_702249_-\|hypothetical-protein	PD-DExK	mkCas0090_PD-DExK_CAS-I:CAS-III	unknown
NC_015276.1\|WP_013659860.1\|702289_702859_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_049787743.1\|711391_711829_-\|transcription-elongation-factor-GreB	unknown	unknown	gnl\|CDD\|179345
NC_015276.1\|WP_013659873.1\|716966_718367_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013659866.1\|708522_709794_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	5.29332e-33
NC_015276.1\|WP_013659858.1\|698596_701470_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.60253e-82
NC_015276.1\|WP_013659874.1\|718553_718802_+\|30S-ribosomal-protein-S16	gnl\|CDD\|234588	PRK00040, rpsP, 30S ribosomal protein S16; Reviewed.	1.83577e-43
NC_015276.1\|WP_013659870.1\|714069_714615_-\|NUDIX-hydrolase	gnl\|CDD\|239948	cd04511, Nudix_Hydrolase_4, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, U=I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.31737e-69
NC_015276.1\|WP_013659865.1\|706612_708520_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	4.16287e-49
NC_015276.1\|WP_013659871.1\|714640_715897_-\|HlyC/CorC-family-transporter	gnl\|CDD\|226911	COG4536, CorB, Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism].	1.7654e-174
NC_015276.1\|WP_013659868.1\|712687_713572_+\|DUF72-domain-containing-protein	gnl\|CDD\|182366	PRK10302, PRK10302, hypothetical protein; Provisional.	3.82679e-60
NC_015276.1\|WP_013659861.1\|702959_704075_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	1.08344e-27
NC_015276.1\|WP_013659863.1\|704493_705396_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	5.37972e-62
NC_015276.1\|WP_013659875.1\|718818_719364_+\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	5.10657e-67
NC_015276.1\|WP_013659872.1\|716014_716782_-\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|226621	COG4137, COG4137, ABC-type uncharacterized transport system, permease component [General function prediction only].	2.83304e-45
NC_015276.1\|WP_049787743.1\|711391_711829_-\|transcription-elongation-factor-GreB	gnl\|CDD\|179345	PRK01885, greB, transcription elongation factor GreB; Reviewed.	1.37031e-82
NC_015276.1\|WP_083799838.1\|704071_704494_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	8.58959e-35
NC_015276.1\|WP_013659869.1\|713662_713974_+\|NIF3-1	gnl\|CDD\|225860	COG3323, COG3323, Uncharacterized protein conserved in bacteria [Function unknown].	8.94465e-36
NC_015276.1\|WP_013659864.1\|705395_706613_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|370625	pfam09700, Cas_Cmr3, CRISPR-associated protein (Cas_Cmr3). CRISPR is a term for Clustered Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This highly divergent family, found in at least ten different archaeal and bacterial species, is represented by TM1793 from Thermotoga maritima.	6.37989e-71
NC_015276.1\|WP_013659857.1\|698321_698600_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.14213e-17
NC_015276.1\|WP_041647746.1\|712187_712691_+\|transcription-elongation-factor-GreB	gnl\|CDD\|179345	PRK01885, greB, transcription elongation factor GreB; Reviewed.	1.35844e-82
NC_015276.1\|WP_013659873.1\|716966_718367_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0

>NC_015276.1|WP_013659866.1|708522_709794_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MARTRLVDSSQLDALQSALSSLDQESQWQTYECTLITPMYGGGVEAGEVDKQMPIRASEIRGHLRFWWRLLYGTQDSKETFDREKAIWGGIAANPKDIKKSLVSIKVTTHAPIHLKPSTTYTDVKNGNTNKINKNSLGYAFGAASILTENEEDICWLSEGTRFTLYIKLDIPEPSHKNKEDIEEQINSSIKYWANFGGLGARTRRGFGSIYSSAFSIKSNTEIESLIKKLTNSKFALLQSKSASAVTAWETASQRLSSFRQIGIGRKSHKNRSTWPEPDQLRRFTDKNDNGKHKPEHKAGNVFPRAAFGMPILFKFKSSSDPQTLRLLPQGAERFASPLIIRPIQLQEGCVAIALLLPNWQQALTQELELQTEKDDTFLVANKEPPMSWGERNGAELASLITPMQGRADNPLEAFLDYFEKGR
>NC_015276.1|WP_013659865.1|706612_708520_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MNTYLITIAIGPVQSLIEAARRTRDLWTGSWVLSECAKAAAKSLHDNQANLPNTGSSCLIFPSPESPETELLPSDFNDQYANISNVIRAEIQAEETDDIKVIAEQAKQAAKNRLTAIAESALNSAKGLPIRRDLWHNQIEHILEMFAVWVKVEDNQYQTASKKLNALLLARKASRHFENPEISEEHGSLLKSSLDGASESVVALEEKDKTTSEESNSIVSFKSGSIKRYKRKLGLANKEVLDALGVIKRLSGKAEQFTPYPRICADDWLNTLSNDQQESLSLHFDKLKNATDSDYGDACLVTDVKGNNNAYSDFPFDGELLYDFRLQNALQNTERDKSLSTSEQRVLGELQNSLRSINSNPVPYGVILKADGDNMGELFSQAQSATQSRAISQALHKFASSVRQLVQKHQGHAIYAGGDDVLAMLPLDQAIPCAEGLIDEFSNCMSSIIQEHHLDITKVPSLSVGLAIGHFMQPLGHLRARAVRAEKLAKGDHLPSDKKRNALSICLGLRSGPEVSWRCRWDDEETINALKTVMNAYSGNAQELSSRTGFAIRSVALQFAWSKTSSEIISPIQQAELKRLLDNLNKKGGEHKISKEMIALLTQQAEHIGLEALADLLIIARWLSAKAMSDLGAME
>NC_015276.1|WP_013659864.1|705395_706613_-|type-III-B-CRISPR-module-associated-protein-Cmr3
MHTHDQKENTYLLDPKAPLIIRSGRPFDEQAGADDARFPPPSTMAGALRAAYARANNIGFNKENTQDILSKAIKGPLPVKQSTEEDIKTLLVPKPEDAQYYYDQAGNIEIVRLSPRELDENEGWDLPRRLLPVSYHDDQEKRHGKPAKGAQWWSLKDLLEWRLHKPINYKEVHKNGWIPPADDIRTHVAINPQSFAAEDGQLFQTSGLPMWQVKKENQSAFPDEKILLAGCINGDLFPEAHSKNDTPQSLNIGGERRLAEILTEDQLWPQPDEQILRDILEGEALSLTLLTPAIFKDGWLPCQQDENGHFIYRPPNTNTLELELVSAAIGRWTAQSGWDLAKHQPKPSRKLVPAGAVYWFRVREGNKHDLEQLWFSNISTKEQDRKDGFGLVLPHSTTLSASGAK
>NC_015276.1|WP_013659863.1|704493_705396_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MDLNIYHLHTHSALHCGTGQSAGIVDLPIARDKATHLPIVPGSSLRGVLRDKIRANEKDIEKALFGPRDIQSSEQSFAGALSLGDANLLVLPIRSLNGIVAYATCPFVLRNYANDTKISVKETPLPQPSAQQALVSNENVNVIQHDNHTELLVLEDLDISAEKDEKVQAWAKKIAEAVYSEQSDLKDEFINRFVVLSDNVFSYLSTTATELRTRIRITEKTGVVKEGALWSEENLPANAILWGVYSLSDSRDKKQELTAPELKEKLSASYTLQMGGNAGIGRGLVSLFTKKEEKETGGQE
>NC_015276.1|WP_083799838.1|704071_704494_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MSVRQHKIAEAAYDCVNKRIEEGIDQKKYAALANKLPNLILQNGLAQATGFLMAKNESTNEHKKLLNDLAFVVNSGHLENQNTPNSDNGKELHQQIIQSDMTKFMQLTQQSLDASGALRRYVQGLMDTNKKDDDSQEETL
>NC_015276.1|WP_013659861.1|702959_704075_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MSSVQLVPQRLFNIYEMHLKSRTSNGLHSGLLLDKGYPASSTGVNTDKEAKARFIKSICGIKASELYTKEFNQWLRLTSKKSNSGKHTNNFEQLPLTLSNRLLIGLNGGGALETGCMINHHNGMPYIPGSSIKGAVRNFASRNLKDHESVWVQFFGNKPEDDLEDPFAGLITFHDAWWIPNSAPSENAGNFSNFPFIQDIVTTHHAEYYSKEGKSLATDFDDPIPNSLISVHGSFLFVIGGNENYLGVVKQMLEKTLKENGIGAKSTAGYGYFDEADESITKQFSILLSDTENTNTTPHSSELIREVSEIKLSKIPDIFGRNRNKTKNEKGKDYRSLCLLVCKHFGDEIANWATESGNKAKAYKELKEFLE
>NC_015276.1|WP_013659860.1|702289_702859_-|hypothetical-protein
MELLTKFWSLLSNYGNALNLIAIVISVIALSRSLSKSVPILYRLGKALSSHEILIYADDRYEDLKETLEDSGLFDPKKIKKVGINNLDKIRSADICIVHYQCAKNSIIKENDRLNLQEHQRDNTISRIINLKSNNNSLIVYAPHGERLQNEEFGLLDSKNNTALTNFRGRLVSDVLISMIAMKRQKALF
>NC_015276.1|WP_013659859.1|701478_702249_-|hypothetical-protein
MNNAKTKSDTDGEQYLKDSFQREQELLESKLLFANQNITHNGERGEVNEKHFIEYLRSHLPKRYSVDSAIVVDSNGKTSNQIDIVVYDNQYTPTLFAQQDFCYVPAEAVYAVIEVKPEVNRDYIEYAQKQAYSVEALERTSIEITHAGGVYKPKPLFKIITGLIALKTGWQEGLASNSFKDAIQMPYTNQTRLDFVTSLQGGHFDCFEKGNEHYSQQNHLTFFLFRLLSQLQSLGTVPAVDWNKYANVLTEQSKPD
>NC_015276.1|WP_013659858.1|698596_701470_-|CRISPR-associated-endonuclease-Cas1
MLNSPLIDAVLPLRSVVITLRWLSPSKTGFLHHAGLHAWVRFLAGSPEQFSDFIVVEPIENGHISYQAGDGYRFRITVLNGGESLLDTLFSSLKRLPESAANHPDIAGAFSDNLVLEKIEDTFEHHQVTQIEDLSVFDINALMLETAVWSRQRRFKVAFNTPARLVKPKPEDGTELKGQNRYCRDKSDLNWQLFTHRLTDTFINLFQSRTGERLQRQNWPEAQLHAGLAVWLNNSYTNKKEKKVKDASGMLAQMQIEIDDDFPADLLALLVLGQYIGMGQNRAFGMGQYQLQDAYGYCSYPRPQAAKSLLEKSLSDASLHQACQTMYPRQANFDSSDTDEEHHDAIDELLTKLYVSRERIFKREFTPSQLHSVEIEKPEGGTRLLSVPNWHDRTLQKAVTECLGNTLEHIWMKHSYGYRKGHSRLQARDQINQYIQQGYEWVLESDIESFFDSVNWLNLEQRLKLLLPNEPLVPLLMQWVSAAKQTEDEQTLARHNGLPQGAPISPILANLLLDDLDQDMIAKGHQIVRYADDFVLLFKSKAAAESALDDIITALKEHHLAINLEKTRIVEASQGFRYLGYLFVDGYAIETKREYRKEHAQLDKQLNASSLENEPSLQQEPAVQNEQSTLIGEREKLGTLLIIAGDIAMLSSEKQRLIVEQYDELHTYPWATLSSVLLVGPHHITTPALKSAMFHNVPVHFASQYGRYQGVSAGAAPSVFGADFWLLQAQYLQQETNALNISQVLIQARIEGIRAVISRREKDAPELNKIQRLDEKRLRAETLDQLRGYEGQASKQLWAFFQRILEEDWGFTGRNRRPPKDPINALLSLGYTYLYSLVDSVNRTVGLYPWQGALHQRHGYHHTLASDLMEPWRYLVEHVVLTLINRHQIHKDDFVIKENGCEMSSGARKTLLKELLVQLTKVPKGGNSLLTEMSNQSYRLALSCKMQQRFIAWSPKR
>NC_015276.1|WP_013659857.1|698321_698600_-|CRISPR-associated-endonuclease-Cas2
MRIYLACFDIEDDKKRRKLSNLLLEYGDRVQYSVFEISLKDENELHKLRKKCSKYTEEADSLRFYWLNKESRKHSQDVWGNPIAVFPAAVLL
>NC_015276.1|WP_049787743.1|711391_711829_-|transcription-elongation-factor-GreB
MDYLWRKERPEITKIVTWAAGLGDRSENADYQYNKRKLREIDRRVRFLRKTLDDIKVVDYHPQQDGKIFFGAWVELEDEDENTIFFRIVGTEEIYGRKDYISIDSPMARACLKKEVDDEVIVKAPSGDKSWVVNKITYRHEQQNI
>NC_015276.1|WP_041647746.1|712187_712691_+|transcription-elongation-factor-GreB
MSRYRPPAPKKSAYLTKEGADKLLAELKYLWKEKRPAVTQTVSDAAKQGDRSENAEYIYGKKQLREIDRRVRYLEKRLDHCTVVDRAPNDVSRIFFGAWVTLEHEDGKLETFRIVGPDELDHHSDYISIDSPVAKALLKKEEGDEVTIRRAEGEKLYYIDSVEYRAL
>NC_015276.1|WP_013659868.1|712687_713572_+|DUF72-domain-containing-protein
MTIHDGQPYLRYGMAQWQHSAWVNWLYSSSVPSAERLREYSKVFQSVEVGSTFYTDIEENQLKRWYDQVNDDFRFCFKAPQTVTHQIVERPFQERLTDWKRFQMKLASLDKKLGPTMVQFPQQLDASSLPEILALIESWELLAPLSIEVRHLHYFDKGEVESEFLRYLSNQSVDKVVMDSRPVFSTEAYSESLKDAQRKKPRVPCHAVATAQSPVVRFIGHPDLERNHVWLDQWAAKLKSWLERGLKPTVFVHSSDNIAAPTLASWLDDKLVANSALPFKQVNLPETQEQIALL
>NC_015276.1|WP_013659869.1|713662_713974_+|NIF3-1
MYSLVFYVPETHLEVVKDAVFAVGGGQIGDYEKCCWQTLGQGQFKPTANATPFIGEAGGDVESVDEYRVEMVLKSELKVQVVTALKSAHPYEEVAYHLISIET
>NC_015276.1|WP_013659870.1|714069_714615_-|NUDIX-hydrolase
MRYCPKCGHQVSMEIPEGDNRQRAVCPQCHHIDYDNPRLITGTIPLFDGKILLCKRNIEPRIGYWTLPAGFMENQETTSEGALRETVEECGSNAICKQAFSMISIPKINQIHLFYIAELPQPDFHATEESSEVALFALDDIPWEDLAFSSVEMTLRLFIEDHSKGSYGFHEDTIRINSIPR
>NC_015276.1|WP_013659871.1|714640_715897_-|HlyC/CorC-family-transporter
MNDVPLGILGGILFFLILFSGFFSSSETSMLSINKYRLKHLVKNGHRSASKASKLLERPDRLIGVILIGNNFVNILASAIATIIAVRIWGDAGVAIATAALTFIILIFAEVTPKTIATIHPEKIAFPASWALTVLLKTLYPLVVIVNTLSNGLIRLLGIKPANSEQNTLNSEELRTIVNEASGLIPAAHQEMLISILDLEKVSVDDIMVPRNEVVGIDIEDSIEEIIEQICQSRHTRMPVYNGEINKVIGVLHARNAALFLREENPTKAALLKATLPPYFIPESTPLNTVLLNFQKDHQQMGIVVDEYGDVQGIAALEDVLEEIVGEFTPPTQDEEEEIQSLEDGAFRIDGSTHIRDINKTLEWHLPTDGPKTLNGLIIETLEFIPERPTSLWVDNYLIEIQEIEDKVVKYAKLHLRR
>NC_015276.1|WP_013659872.1|716014_716782_-|cytochrome-c-biogenesis-protein-CcsA
MTQLTLWLACITSIVAGGTYFKRPGAQMTQLFGSLAIGIHMLALVQLLRSQDGFNFLTIGLLIALIGNTFLWFSNRNKDLSLLLCFAYPLAAIIIALNAIEPWKLEQLHSQSFGTSIHILIASVAYSLFMAACGVGILLSIQEHQLKHHKLKQLLRVPPLQVLERLMFEFLWAAFILLTATIATGFYFIEDMFAQHLAHKTFFTISSWLVFASLLVGRHFLGWRGQLSVKWTLSGFILLMLAYFGSKIALQIISM
>NC_015276.1|WP_013659873.1|716966_718367_+|signal-recognition-particle-protein
MFDNLSNRLTSSLDKIRGRAKLTEDNIKDVLREVRMALLEADVALPVVKDFIAAVKERAVGTEVTKSLSPGQVFLKIVKQELEAVMGQANDELNLRATPPAVILLAGLQGAGKTTSAGKLAKFLKERQKKSVAVVSADVYRPAAIKQLETLASDVGVDFIPSDISQKPIDIANNAIDVARKAHKDVLIVDTAGRLAIDEDMMAEIKALHGAINPVETLFVVDSMTGQDAANTAKAFGDVLPLTGVILTKTDGDARGGAALSVRHITGKPIKFLGVGEKTDALEPFHPDRLASRILGMGDMLSLIEQAEQKIDKEKAEKLAGKLQKGKGFDLEDFKEQLQQMKNMGGMTSMLDKLPGMGQLGDIQDKVNDKMFVQMEALINSMTPAERRFPDKINGSRKKRISTGAGLQIQDLNRLLKQHKQMQKMMKKMGSKGGMKKMMRGLGGMMPGGLPGGGGNFPGGGFPPKF
>NC_015276.1|WP_013659874.1|718553_718802_+|30S-ribosomal-protein-S16
MVTIRLSRGGSKKRPFYHLNVADSRRARDGRYIERVGFFNPIARGQEERLRVDLDRVNHWVGQGAQLSDRVAQLVKEADKNA
>NC_015276.1|WP_013659875.1|718818_719364_+|ribosome-maturation-factor-RimM
MSALKQATAPEQALVVGRITSVYGVKGWVKLYSHTEPMTGIFDYSHWWLKTSTGWKRIELNQGRTQGRGLVASIKGYADRDIVREICGQDIYIDVKDLPELDDGDFYWSQLEGLTVTTKEGVLLGKVSQLMETGANDVVVVRACEGSYDREERLIPYVPETYILDVNLESKAMVVDWDPEF

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Crispr_ID: NC_015276_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_4

1731633-1732016

Orphan

Consensus_repeat	Method
TGCCGGTATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGA	PILER-CR

3 spacers

The CRISPR arrays of NC_015276_4

>merge|NC_015276|4|1731633-1732016|PILER-CR
GCCGATATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGAGTTCGACTCTTGGTGTCGGCACCATTTCTTGGTAAATACAATTTGTTTTAGTTCTTTATGCCGGTATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGAGTTCGACTCTTGGTGCCGGCACCATCTCTAAGCGAGTTTCTCGCCGAGTTTGTAAAAGAAATAAAGCATGTTTGCCGGTATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGAGTTCGACTCTTGGTGCCGGCACCATTACATCGCAAAACATATCTGCCGGTATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGA

>NC_015276|4|6|1731633-1732016|PILER-CR
GCCGATATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGAG	TTCGACTCTTGGTGTCGGCACCATTTCTTGGTAAATACAATTTGTTTTAGTTCTTTAT
GCCGGTATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGAG	TTCGACTCTTGGTGCCGGCACCATCTCTAAGCGAGTTTCTCGCCGAGTTTGTAAAAGAAATAAAGCATGTTT
GCCGGTATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGAG	TTCGACTCTTGGTGCCGGCACCATTACATCGCAAAACATATCT
GCCGGTATAGCTCAGTTGGTAGAGCATCTGACTTGTAATCAGAGGGTCCCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013660733.1\|1742808_1743672_+\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119324
NC_015276.1\|WP_013660726.1\|1735540_1735939_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100005
NC_015276.1\|WP_013660719.1\|1724520_1725423_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_041647817.1\|1733793_1734138_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_015276.1\|WP_013660728.1\|1736916_1737933_-\|ring-hydroxylating-dioxygenase-ferredoxin-reductase-family-protein	unknown	unknown	gnl\|CDD\|99805
NC_015276.1\|WP_013660729.1\|1738035_1738530_-\|benzoate-1,2-dioxygenase-small-subunit	unknown	unknown	gnl\|CDD\|132276
NC_015276.1\|WP_013660722.1\|1728081_1728408_+\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|235518
NC_015276.1\|WP_013660731.1\|1740218_1741181_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
NC_015276.1\|WP_013660715.1\|1721964_1722372_-\|ectoine-synthase	unknown	unknown	gnl\|CDD\|183953
NC_015276.1\|WP_013660725.1\|1734304_1735486_-\|benzoate/H(+)-symporter-BenE-family-transporter	unknown	unknown	gnl\|CDD\|281578
NC_015276.1\|WP_190273431.1\|1726853_1727972_+\|tRNA-guanosine(34)-transglycosylase-Tgt	unknown	unknown	gnl\|CDD\|234642
NC_015276.1\|WP_013660727.1\|1736119_1736905_-\|1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate-dehydrogenase	unknown	unknown	gnl\|CDD\|183772
NC_015276.1\|WP_013660730.1\|1738540_1739887_-\|benzoate-1,2-dioxygenase-large-subunit	unknown	unknown	gnl\|CDD\|132273
NC_015276.1\|WP_013660720.1\|1725759_1726821_+\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	unknown	unknown	gnl\|CDD\|234666
NC_015276.1\|WP_013660716.1\|1722384_1723680_-\|diaminobutyrate--2-oxoglutarate-transaminase	unknown	unknown	gnl\|CDD\|236437
NC_015276.1\|WP_013660724.1\|1730347_1731262_+\|protein-translocase-subunit-SecF	unknown	unknown	gnl\|CDD\|237275
NC_015276.1\|WP_013660714.1\|1721104_1721920_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_015276.1\|WP_013660732.1\|1741490_1742666_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380667
NC_015276.1\|WP_013660717.1\|1723699_1724203_-\|diaminobutyrate-acetyltransferase	unknown	unknown	gnl\|CDD\|131459
NC_015276.1\|WP_013660723.1\|1728484_1730338_+\|protein-translocase-subunit-SecD	unknown	unknown	gnl\|CDD\|235615

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013660733.1\|1742808_1743672_+\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119324	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	2.64717e-68
NC_015276.1\|WP_013660726.1\|1735540_1735939_-\|RidA-family-protein	gnl\|CDD\|100005	cd02198, YjgH_like, YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	8.57585e-46
NC_015276.1\|WP_041647817.1\|1733793_1734138_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	9.25198e-19
NC_015276.1\|WP_013660728.1\|1736916_1737933_-\|ring-hydroxylating-dioxygenase-ferredoxin-reductase-family-protein	gnl\|CDD\|99805	cd06209, BenDO_FAD_NAD, Benzoate dioxygenase reductase (BenDO) FAD/NAD binding domain. Oxygenases oxidize hydrocarbons using dioxygen as the oxidant. As a Class I bacterial dioxygenases, benzoate dioxygenase like proteins combine an [2Fe-2S] cluster containing N-terminal ferredoxin at the end fused to an FAD/NADP(P) domain. In dioxygenase FAD/NAD(P) binding domain, the reductase transfers 2 electrons from NAD(P)H to the oxygenase which insert into an aromatic substrate, an initial step in microbial aerobic degradation of aromatic rings. Flavin oxidoreductases use flavins as substrates, unlike flavoenzymes which have a flavin prosthetic group.	1.54679e-121
NC_015276.1\|WP_013660729.1\|1738035_1738530_-\|benzoate-1,2-dioxygenase-small-subunit	gnl\|CDD\|132276	TIGR03232, benzo_1_2_benB, benzoate 1,2-dioxygenase, small subunit. Benzoate 1,2-dioxygenase (EC 1.14.12.10) belongs to the larger family of aromatic ring-hydroxylating dioxygenases. Members of this family should all act on benzoate, but several have additional known activities on various benozate analogs. Some members actually may be named more suitably according to such alternate an activity, such as 2-chlorobenzoate 1,2-dioxygenase (1.14.12.13).	6.16008e-73
NC_015276.1\|WP_013660722.1\|1728081_1728408_+\|preprotein-translocase-subunit-YajC	gnl\|CDD\|235518	PRK05585, yajC, preprotein translocase subunit YajC; Validated.	6.5908e-47
NC_015276.1\|WP_013660731.1\|1740218_1741181_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	8.59728e-19
NC_015276.1\|WP_013660715.1\|1721964_1722372_-\|ectoine-synthase	gnl\|CDD\|183953	PRK13290, ectC, L-ectoine synthase; Reviewed.	3.60353e-78
NC_015276.1\|WP_013660725.1\|1734304_1735486_-\|benzoate/H(+)-symporter-BenE-family-transporter	gnl\|CDD\|281578	pfam03594, BenE, Benzoate membrane transport protein.	2.42781e-131
NC_015276.1\|WP_190273431.1\|1726853_1727972_+\|tRNA-guanosine(34)-transglycosylase-Tgt	gnl\|CDD\|234642	PRK00112, tgt, queuine tRNA-ribosyltransferase; Provisional.	0
NC_015276.1\|WP_013660727.1\|1736119_1736905_-\|1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate-dehydrogenase	gnl\|CDD\|183772	PRK12823, benD, 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Provisional.	7.89009e-165
NC_015276.1\|WP_013660730.1\|1738540_1739887_-\|benzoate-1,2-dioxygenase-large-subunit	gnl\|CDD\|132273	TIGR03229, benzo_1_2_benA, benzoate 1,2-dioxygenase, large subunit. Benzoate 1,2-dioxygenase (EC 1.14.12.10) belongs to the larger family of aromatic ring-hydroxylating dioxygenases. Members of this family all act on benzoate, but may have additional activities on various benozate analogs. This model describes the large subunit. Between the trusted and noise cutoffs are similar enzymes, likely to act on benzoate but perhaps best identified according to some other activity, such as 2-chlorobenzoate 1,2-dioxygenase (1.14.12.13). [Energy metabolism, Other].	0
NC_015276.1\|WP_013660720.1\|1725759_1726821_+\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	gnl\|CDD\|234666	PRK00147, queA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional.	0
NC_015276.1\|WP_013660716.1\|1722384_1723680_-\|diaminobutyrate--2-oxoglutarate-transaminase	gnl\|CDD\|236437	PRK09264, PRK09264, diaminobutyrate--2-oxoglutarate transaminase.	0
NC_015276.1\|WP_013660724.1\|1730347_1731262_+\|protein-translocase-subunit-SecF	gnl\|CDD\|237275	PRK13022, secF, protein translocase subunit SecF.	1.41263e-137
NC_015276.1\|WP_013660714.1\|1721104_1721920_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.18095e-05
NC_015276.1\|WP_013660732.1\|1741490_1742666_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380667	cd20014, PBP1_RPA0668_benzoate-like, type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs. This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).	5.49004e-154
NC_015276.1\|WP_013660717.1\|1723699_1724203_-\|diaminobutyrate-acetyltransferase	gnl\|CDD\|131459	TIGR02406, L-24-diaminobutyric_acid_acetyltransferase, diaminobutyrate acetyltransferase. This enzyme family is the EctA of ectoine biosynthesis. Ectoine is a compatible solute, analagous to trehalose, betaines, etc., found often in halotolerant organisms. EctA is L-2,4-diaminobutyric acid acetyltransferase, also called DABA acetyltransferase. [Cellular processes, Adaptations to atypical conditions].	6.28425e-60
NC_015276.1\|WP_013660723.1\|1728484_1730338_+\|protein-translocase-subunit-SecD	gnl\|CDD\|235615	PRK05812, secD, preprotein translocase subunit SecD; Reviewed.	0

>NC_015276.1|WP_013660724.1|1730347_1731262_+|protein-translocase-subunit-SecF
MKVTNIPFMAMRKIVAMFSVLLILISIGSLATKGLQFGLDFTGGTLVEVKYDEAPNLDDVRAVLAQNNYSDVVVQNFGSPTDVVVRMANSYTATLGDEVLVALKENGKVGVSLQRSEFVGAQVGEELREQGGLGMLLALAIVMLYVAVRFQFKFSIASVAALAHDVVITLGVFSLFEIEFDLTVLAALLAVIGYSLNDTIVVCDRIRENFRIMRETEPEELINESINQTLGRTIITSMTTLFVLVVLFLFGGEAINNFSFALLVGIVIGTYSSIFVAANLLLAQNIKKEDLIPAPKEELEDELP
>NC_015276.1|WP_013660723.1|1728484_1730338_+|protein-translocase-subunit-SecD
MLNKYPLWKYLLILAVLVFGVVYALPNLYPDDPALQISTQKATSTVDERTLKTARNALDKAGIELKAAELTSAGGTLRFDNGEDQLAAKPVIAAALGDGYVTALNLVPTTPDWLASLGAGPAKLGLDLRGGVHFLLEVDTPAALKQRLEVAGSEMKAALRKERIRYRSVEIKDGVMSIRFLKDSDRDLAESLLKDDFGDYLYRTVEDGKSFFLTIGFSEAEQKEIEAYALEQNLTTLRNRVNELGVAEPLVQRQGSNRIVVELPGVQDTAAAKRIIGATANLEFRLEAGLDANASDTETLTFRNGSGRTAQLEKDIIITGDSVSDANSSFDENGRPQVNISLDSKGGKQMAKVTRSAVGRNMAVVFIEHKSRSRFVEQEDGSLKEVRRSYSEKGIISLATIQTTLGNSFRITGLDSPRESSELALLLRAGALAAPIYFVEERTIGPSLGAENIKLGVTSAQIGMLVVMLFMLIYYKVFGVFANVSLILNIVLLMAFMSLMSATLTLPGIAGIVLTMGMAVDANVLIFSRIKEELANGLPSQQAIHSGFNRAFTTIFDANITTLLVAVILFAVGTGPVKGFAVTLSLGILTSMFTAIVVTRAQVNLVYGGRKNKRLYI
>NC_015276.1|WP_013660722.1|1728081_1728408_+|preprotein-translocase-subunit-YajC
MIALISPAYAEGGAPADAGIFNIVLLVGFVIIFYFLMWRPQAKRAKEHRNLIASLAKGTEVVTSGGILGKVTKVDDNYIVLEVSDEVEMKFQKASVTSVLPKGTLKSI
>NC_015276.1|WP_190273431.1|1726853_1727972_+|tRNA-guanosine(34)-transglycosylase-Tgt
MDFEVHATSGKARRATLSFPRGNVETPAFMPVGTYGTVKGMLTKDIEEIGADIILGNTFHLWLRPGTEVVKEHGDLHDFTQWKKPILTDSGGFQVFSLGEMRKITEDGVSFRSPVDGSKVFLNPEISMEVQRELGSDIVMIFDECTPYPATETEAAKSMRMSLRWAQRSKDAHGDSPSALFGIIQGSMYENLRDESLEGLTDIGFDGYAIGGLSVGEPKHEMMKVLDHVAHKMPEDKPRYLMGVGKPEDLVEGVRRGVDMFDCVMPTRNARNGHLFTSDGVVRIRNAKNRHDTRPLDEECDCYTCKNFSRAYLHHLDKCQEMVGAQLNTIHNLRYYQTLMAGLRTALDEGRFDAFVDEFYAKRGMETPPLSK
>NC_015276.1|WP_013660720.1|1725759_1726821_+|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA
MKVSDYHFNLPDELIARYPMPERSSSRLLQLHGQTGELKHGVFSDVLSLVEPGDLMVFNNTRVIPARVFGQKASGGKVEVLVERLLSSTEILAHVRASKSPKPGNELYLGTDRNESFKAVMVERDANLFRLQFENPVLEVLEKVGHMPLPPYIERPDEDSDQERYQTVYNEKPGAVAAPTAGLHFDDELLEKLAEKGVDTAFVTLHVGAGTFQPVKVDDVKDHIMHSEYAEVSQEVVDKVRQAKANGKRVIAVGTTSVRSLESASQSGQIEPMADDTSIFIYPGYEFKTVDALVTNFHLPESTLIMLISAFAGYSNVMAAYKAAVDEKYRFFSYGDAMFITRNPEASGPQSEE
>NC_015276.1|WP_013660719.1|1724520_1725423_+|hypothetical-protein
MSYARSIVLVVFAVILSACAGRATDPEAQMKRIDADFRFVNKLTCSIRNKENDEFCSCQVDVLSEVTPDGLKRKLVRGRASSAQYELAEIMVENSDRLEACKANYSSKSLLKAEPESNALHQVLIKYKDKILAPGDEQEFDHSHLSLGHRYILQNQIADTEGKLSVPLNATLTKIEGAAFYYSVYVGEEDKTYENVIAWKNGVLYRVGKGGDLIPYYSDSACKFVIGVCEYKDYRGKSRYVNTEYINGVWVRNLKGVGSKQRLVKEVFDKDGMILYQLNKSLGKWEYVRVDEANLSLSEK
>NC_015276.1|WP_013660717.1|1723699_1724203_-|diaminobutyrate-acetyltransferase
MLESRAIRFHEPIRLNGKEVYDLVKNSPPLDENSMYCNFLQCEHFSDTSVCAKQGDTLVGFISAYLLPNNNNTLFIWQVAISKEARGQGLALKMIEHLLERLHLKNVCHIETTITHENQSSWRLFEKVASALSCEIHSSEWLNKETHFQSQHSTEMLVKIGPFQTQH
>NC_015276.1|WP_013660716.1|1722384_1723680_-|diaminobutyrate--2-oxoglutarate-transaminase
MKIFEEIESEVQCYARSFPCVFNRAKGEFMWDEDGNRYLDFLAGAGTLNYGHNNALLKKELLNYIENDGITHGLDMHTKAKGEFLQTFSDKILKPRNLRYTVQFTGPTGTNAVEAAMKIARNVTGQSNIVTFTNGFHGVSLGALAATGNSHHRDAAGTSLTGTHRIPYDGYLGDNIDTTEYLDKVLSDSSSGINSPAAVIVETVQGEGGINAARIEWLRSLQTVCRKHSILLIIDDIQAGCGRTGDYFSFEEAGLEPDIVTLSKSLGGYGLPFAVVLMKPELDQWKPGEHNGTFRGNNLAFVTAKHAIDHYWSDNHFSNEIKRKGQYVSQRLTAMADKFGDGKFTVKGRGMFQGINCINGEIAGKITKNAFTKGLLIETSGADDQVVKLLCPLIIGDENLKAGLDIVELAIQETCEDFDSFPNETLYFKAS
>NC_015276.1|WP_013660715.1|1721964_1722372_-|ectoine-synthase
MIVRNLADAEKSNRRIVSPEGSWESTRLLLKDDNMGFSFHITTIYKDADFQLHYKNHLESVYCMSGRGEVEDLATGEKHPITPGTVYILDKHDKHMLRAFEEMKMACVFNPPITGAEVHNSEGAYELEDTPLATL
>NC_015276.1|WP_013660714.1|1721104_1721920_+|helix-turn-helix-transcriptional-regulator
MNLDFQNNLRLLCSYYKSIAEVCRRLQINRPQFNRYLNGKTVPADSTMRRICDFFGVTQSEMLLPHNQFQRLVQARPINQDTSVSERSIEQTHFDRLNHVGQKDLDKYCGYYFEYYISMSCPGQILRTLVHIESQDGKTYYQRIERFNPKTSKKPFHGIYQGVVQFLSDRLFLMDYEAHTKVEVTQTILYPSFKNRVERLKGLRLGVSGSGERVPCCVRVVYEYLGKSLDRKKALSMSGLYDMASNEIDDDIKEAIRNDIDEGEWHFRGRF
>NC_015276.1|WP_041647817.1|1733793_1734138_+|LysR-family-transcriptional-regulator
MALPAAAEELNLTRSAVSHQLSMLEDVVGFPLTKRDGRGLVLTQKGKSYAIEAKKALMILLEASHVNDGEEVTGELIVSCAPGLANYWLCHKISTFTNKSMQGTRPPFRQIGSY
>NC_015276.1|WP_013660725.1|1734304_1735486_-|benzoate/H(+)-symporter-BenE-family-transporter
MLKDLHISTITAGLVAVLVSYSGPLAIFFQAANSANISQEMMTSWVFAISIGAAISGIALSIYFRIPIITAWSAPGTALLVTLFPNLSLNEAVGAYITAAIIIFCIGISGWFDAVIRWIPKSVAAAMMAGILFNFGISAFQAFNSVPVLTFLMLIGFVVFKAISKTYCLILLVVLCSILSITVLHADFSHFTWQLASPIWISPQWSWSSTFSLALPLVIVSLTGQFLPGFTILKTFNYHVPTRPVISVLGLVSLPIAFFGGITTVIAAITAPICTSPDAHPDHNKRYIAGIFNGVFYLIGGIFAGSIVLFFTTFPAQMIAIIAGLALLGAIFNSLSLALEDKSNIDAATITFMTTASGIQLLGIGSAFWGVVLGTGVYTLIRAMRTQKARQEL
>NC_015276.1|WP_013660726.1|1735540_1735939_-|RidA-family-protein
MTTTKRKAIVPKGMEFVRDDIGYAPAVLVGNTLYISGQIGRNAERQLVEDRRQQFIQCFDNMKAVLEEAGMTFSHVVEVTSYHTDMRDLPLYMEIRDLYFGDCLPAWTAIGAASLCGIPGYFLEVKAIAVKT
>NC_015276.1|WP_013660727.1|1736119_1736905_-|1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate-dehydrogenase
MRAPRFENKVAVVTGSAQSIGRQVALQMAQEHATLVLLDRSELIYDVAEEAKAAGAEDVLVIIADLEKFTDSHNAINASVEKFGRIDILINNVGGTIWAKPFEHYEEAQIEAEIRRSLYPTLWCCHAVLETMQRQKSGNIINVSSIATRSINRTPYSAAKGGVNAMTASLAFENAKHGIRVNAVAPGGTDVGERKIPRNLEAMSEQEKIWYQEIVDQTIDSSLMGRYSSTEEQANVILFFASDESSYLTGSLLPVGGGDLG
>NC_015276.1|WP_013660728.1|1736916_1737933_-|ring-hydroxylating-dioxygenase-ferredoxin-reductase-family-protein
MYKIALNFEDGVTRFVQTLSGETVADAAYRSGLNIPMDCRDGACGTCKCKSESGQFEMEGYIEDALSDEEVEAGMVLTCCMRLETDCAISVPASSEVCVRSAQEDITGTIFDIKRLSDSTLSFSIAGDQVQSMNFLPGQYVNVHVPETDQKRAYSFSSLVQKENDAASFLIRMVPNGLMSTFMAETAKIGDSLTLSGPFGSFYLRDIKRPVLMLAGGTGLAPFLAMLESIKATGTNHPIHLIYGVTHDADLVEMEKLEALTSTMEQVTFSACVASEESNWPLKGYVTQHISPSHLNDGDLDIYLCGPPPMVEAVSQFMNEKDITPVNFYYEKFAASSH
>NC_015276.1|WP_013660729.1|1738035_1738530_-|benzoate-1,2-dioxygenase-small-subunit
MTIQYDEVRNFLYAEARCLDDKQWDEWLTYYHPEVDYWMPSWDDDGELVTDPQREVSLMYYPHKGGLEDRIFRIKTERSSASSLPEARTSHMINNIEIMNSSGDSTEVRYNWCTNSYRYQTVDTYFGTTSITLVTNEDGQIQIKRKKIILVNDYIHHVIDVYHV
>NC_015276.1|WP_013660730.1|1738540_1739887_-|benzoate-1,2-dioxygenase-large-subunit
MHNELITKIKSMMEVDTDKGLYRARRDMFTDPELFDLEMKHIFEGNWIYLAHESQIPNKNDFFTGYMGRQPIFITRNKDDELNCFINACSHRGAMLCRTKKGNKSVMTCPFHGWSFNNSGKLIKVKDATDAGYPASFNCDGSHNLKKVACFESYRGFLFGSINPDVKPLTEHLGEAAKIIDMIVDQSPQGLEVLRGSSTYTYDGNWKMQAENGADGYHVSSVHWNYVATTSRRKLGPVEDETKAMDASTWNKQQGGFYAFEQGHILLWLRWPNPEDRPLAERRAALEKDFGVEKADWMISNLRNLCLYPNVFLMDQFSSQIRTFRPISANQTEVTIYCIAPKGESDTARAQRIRQYEDFFNASGMATPDDLEEFRSCQQGFLASDLPWNDLSRGAEHWVKGPDEAAEKINLNPLLSGRKSEDEGLFKTQHQYWVETMTSAIQKDNEQQ
>NC_015276.1|WP_013660731.1|1740218_1741181_+|AraC-family-transcriptional-regulator
MFANALSNAVIFNQAHPLEVSDYINSHIGHHTLLPESVRDSDEFCSQLKHRDFAELGLSSIHYGNEVKIHCADLNDIYHFQVVTRGQCCWQFEEESLLLKPGQALMMNPHEKMDISYSADCEKIIVKVPQTFIRDLCLEQNRVISSSGILFERKVIELDKSLGFLSLMGAILHEANDAELDLLQMQLPYRDLLIRKLFQQFDNNTPALLDSDPNDRNFTALLQHIEENIKEDIGVEELANVGHISVRKVYNLFAKHYHITPKVFIKQSKLKHLRQEIITNNNIRNITEIALDYGFSHLGRFSSDYRKMFSELPSETLKRR
>NC_015276.1|WP_013660732.1|1741490_1742666_+|ABC-transporter-substrate-binding-protein
MKNKNKILNTALLGMSLVSLSSSVIAADQGPIKVGVMLPFSGVYGGLGEATRNGLKMALQEHAEDLKGRDIEFIEMDTEAKPSRAPEIANSLLNKSHADFIIGPVHSGVAMGMIKVLKKKDTIMIIPNAGANAATGPLCAPNIFRTSFSAWQPSYPMGKIALEQGFKKVVTLSWNYGFGKESLDAFEESFTSGGGEIVKKMLIPFPKTEFQSYLSEIGSIQPDAVFVFFAGGGAVKFVKDYDAMGLKGKIPLLGAGFLTEGTLAAQGDSAEGVLTTLHYADPLDNAENNAFRKNYSEKFGKPSDLYAVQGYDTGLMIASAVNALNGDISDQKALINALENTKIKSPRGDFTFSKAHNPIQNVYLRRVENGENQVVKLAAPDLEDPARGCLM
>NC_015276.1|WP_013660733.1|1742808_1743672_+|branched-chain-amino-acid-ABC-transporter-permease
MDSTLFFVQLINGLQYGLLLFLIASGLTLVFGVMGILNLAHGSMFMVGAYLAWYFVQQTGSFAASAAISAVIALLIGFVVERTLIRRLYKRNHLDQVLLTIGMIFVFNAMQGLLWGNDPLGVDVPEALSASIPLTGIIEYPVYRIFVALFCVVVAVGMYYVINKTRLGMLIRAGESDREMVECLGIDINRLYTIVFAIGVMLSAVAGVVAAPISSIVPGMGEHILITCFVVVVIGGMGSIKGAFIGALMVGLVDTFASVLVPELSSMMIYIFMAFILLIKPQGLFSS

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Crispr_ID: NC_015276_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_5

2572933-2573059

Orphan

Consensus_repeat	Method
GGGGAGGAGCAAGTTGCGAGTCAGGTTTAACTGGGGGATTTAGTAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015276_5

>merge|NC_015276|5|2572933-2573059|CRISPRCasFinder
GGGGAGGAGCAAGTTGCGAGTCAGGTTTAACTGGGGGATTTAGTAGACAAGACCCCCTCCCAACCTCCCCCTTAAACAAGGGGGAGGAGCAAGTTGCGAGTCAGGTTTAACTGGGGTATTTAGTAGA

>NC_015276|5|4|2572933-2573059|CRISPRCasFinder
GGGGAGGAGCAAGTTGCGAGTCAGGTTTAACTGGGGGATTTAGTAGA	CAAGACCCCCTCCCAACCTCCCCCTTAAACAAG
GGGGAGGAGCAAGTTGCGAGTCAGGTTTAACTGGGGTATTTAGTAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013661485.1\|2574110_2575964_+\|penicillin-binding-protein-activator	unknown	unknown	gnl\|CDD\|380562
NC_015276.1\|WP_013661481.1\|2569488_2570271_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013661487.1\|2576317_2576911_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|237567
NC_015276.1\|WP_013661480.1\|2568490_2569276_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013661490.1\|2579799_2580279_-\|YcgN-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|235356
NC_015276.1\|WP_013661482.1\|2570524_2571769_+\|YcaO-like-family-protein	unknown	unknown	gnl\|CDD\|376866
NC_015276.1\|WP_013661484.1\|2573212_2574076_-\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|223390
NC_015276.1\|WP_013661493.1\|2581736_2582330_-\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NC_015276.1\|WP_013661477.1\|2565723_2566464_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013661491.1\|2580278_2580569_-\|YcgL-domain-containing-protein	unknown	unknown	gnl\|CDD\|377477
NC_015276.1\|WP_013661483.1\|2571768_2572881_+\|TfuA-domain-containing-protein	unknown	unknown	gnl\|CDD\|380274
NC_015276.1\|WP_013661475.1\|2560263_2561313_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238017
NC_015276.1\|WP_013661492.1\|2580583_2581735_-\|ribonuclease-D	unknown	unknown	gnl\|CDD\|130455
NC_015276.1\|WP_013661479.1\|2567143_2568301_+\|S53-family-peptidase	unknown	unknown	gnl\|CDD\|173788
NC_015276.1\|WP_013661488.1\|2577005_2577788_-\|class-II-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|372525
NC_015276.1\|WP_041647905.1\|2577780_2579676_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238742
NC_015276.1\|WP_013661478.1\|2566644_2566944_+\|DUF1330-domain-containing-protein	unknown	unknown	gnl\|CDD\|377765
NC_015276.1\|WP_013661476.1\|2561337_2565711_+\|protein-kinase	unknown	unknown	gnl\|CDD\|274846
NC_015276.1\|WP_013661474.1\|2558596_2559373_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|272971
NC_015276.1\|WP_013661486.1\|2575920_2576313_+\|YraN-family-protein	unknown	unknown	gnl\|CDD\|237119

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013661485.1\|2574110_2575964_+\|penicillin-binding-protein-activator	gnl\|CDD\|380562	cd06339, PBP1_YraM_LppC_lipoprotein-like, periplasmic binding component of lipoprotein LppC, an immunodominant antigen. This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).	4.91013e-60
NC_015276.1\|WP_013661487.1\|2576317_2576911_+\|SIS-domain-containing-protein	gnl\|CDD\|237567	PRK13936, PRK13936, phosphoheptose isomerase; Provisional.	4.10026e-66
NC_015276.1\|WP_013661488.1\|2577005_2577788_-\|class-II-glutamine-amidotransferase	gnl\|CDD\|372525	pfam13230, GATase_4, Glutamine amidotransferases class-II. This family captures members that are not found in pfam00310.	6.58487e-126
NC_015276.1\|WP_013661490.1\|2579799_2580279_-\|YcgN-family-cysteine-cluster-protein	gnl\|CDD\|235356	PRK05170, PRK05170, YcgN family cysteine cluster protein.	1.34779e-66
NC_015276.1\|WP_013661482.1\|2570524_2571769_+\|YcaO-like-family-protein	gnl\|CDD\|376866	pfam02624, YcaO, YcaO cyclodehydratase, ATP-ad Mg2+-binding. YcaO is an ATP- an Mg2+-binding protein involved in the peptidic biosynthesis of azoline. There three motifs involved in the binding are, in UniProtKB:P75838, 71-79: Sx3ExxER, 184-203: Sx6Ex3Qx3ExxER, and 286-290: RxxxE. Three slightly different functional families are represented in this family, proteins involved in TOMM (thiazole/oxazole-modified microcin) biogenesis, non-TOMM proteins such as UniProtKB:P75838, and TfuA-associated non-TOMM proteins involved in trifolitoxin biosynthesis. UniProtKB:P75838 hydrolyzes ATP to AMP and pyrophosphate.	2.23948e-92
NC_015276.1\|WP_013661475.1\|2560263_2561313_+\|FHA-domain-containing-protein	gnl\|CDD\|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	4.78745e-11
NC_015276.1\|WP_013661493.1\|2581736_2582330_-\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	8.80062e-111
NC_015276.1\|WP_013661484.1\|2573212_2574076_-\|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase	gnl\|CDD\|223390	COG0313, COG0313, Predicted methyltransferases [General function prediction only].	1.34958e-121
NC_015276.1\|WP_013661483.1\|2571768_2572881_+\|TfuA-domain-containing-protein	gnl\|CDD\|380274	NF033432, ThioGly_TfuA_rel, TfuA-related McrA-glycine thioamidation protein.	2.79342e-65
NC_015276.1\|WP_013661492.1\|2580583_2581735_-\|ribonuclease-D	gnl\|CDD\|130455	TIGR01388, Ribonuclease_D, ribonuclease D. This model describes ribonuclease D, a 3'-exonuclease shown to act on tRNA both in vitro and when overexpressed in vivo. Trusted members of this family are restricted to the Proteobacteria; Aquifex, Mycobacterial, and eukaryotic homologs are not full-length homologs. Ribonuclease D is not essential in E. coli and is deleterious when overexpressed. Its precise biological role is still unknown. [Transcription, RNA processing].	7.79523e-105
NC_015276.1\|WP_013661479.1\|2567143_2568301_+\|S53-family-peptidase	gnl\|CDD\|173788	cd04056, Peptidases_S53, Peptidase domain in the S53 family. Members of the peptidases S53 (sedolisin) family include endopeptidases and exopeptidases sedolisin, kumamolysin, and (PSCP) Pepstatin-insensitive Carboxyl Proteinase. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of Asn in subtilisin. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values. Characterized sedolisins include Kumamolisin, an extracellular calcium-dependent thermostable endopeptidase from Bacillus. The enzyme is synthesized with a 188 amino acid N-terminal preprotein region which is cleaved after the extraction into the extracellular space with low pH. One kumamolysin paralog, kumamolisin-As, is believed to be a collagenase. TPP1 is a serine protease that functions as a tripeptidyl exopeptidase as well as an endopeptidase. Less is known about PSCP from Pseudomonas which is thought to be an aspartic proteinase.	8.05793e-67
NC_015276.1\|WP_041647905.1\|2577780_2579676_-\|VWA-domain-containing-protein	gnl\|CDD\|238742	cd01465, vWA_subgroup, VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the VWA domain in these proteins. The members do have a conserved MIDAS motif. The biochemical function however is not known.	7.84296e-11
NC_015276.1\|WP_013661478.1\|2566644_2566944_+\|DUF1330-domain-containing-protein	gnl\|CDD\|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	8.07544e-24
NC_015276.1\|WP_013661491.1\|2580278_2580569_-\|YcgL-domain-containing-protein	gnl\|CDD\|377477	pfam05166, YcgL, YcgL domain. This family of proteins formerly called DUF709 includes the E. coli gene ycgL. homologs of YcgL are found in gammaproteobacteria. The structure of this protein shows a novel alpha/beta/alpha sandwich structure.	2.0609e-35
NC_015276.1\|WP_013661476.1\|2561337_2565711_+\|protein-kinase	gnl\|CDD\|274846	TIGR03903, TOMM_kin_cyc, TOMM system kinase/cyclase fusion protein. This model represents proteins of 1350 in length, in multiple species of Burkholderia, in Acidovorax avenae subsp. citrulli AAC00-1 and Delftia acidovorans SPH-1, and in multiple copies in Sorangium cellulosum, in genomic neighborhoods that include a cyclodehydratase/docking scaffold fusion protein (TIGR03882) and a member of the thiazole/oxazole modified metabolite (TOMM) precursor family TIGR03795. It has a kinase domain in the N-terminal 300 amino acids, followed by a cyclase homology domain, followed by regions without named domain definitions. It is a probable bacteriocin-like metabolite biosynthesis protein. [Cellular processes, Toxin production and resistance].	3.52228e-135
NC_015276.1\|WP_013661474.1\|2558596_2559373_-\|PAS-domain-containing-protein	gnl\|CDD\|272971	TIGR00229, Sensor_protein_FixL, PAS domain S-box. The PAS domain was previously described. This sensory box, or S-box domain occupies the central portion of the PAS domain but is more widely distributed. It is often tandemly repeated. Known prosthetic groups bound in the S-box domain include heme in the oxygen sensor FixL, FAD in the redox potential sensor NifL, and a 4-hydroxycinnamyl chromophore in photoactive yellow protein. Proteins containing the domain often contain other regulatory domains such as response regulator or sensor histidine kinase domains. Other S-box proteins include phytochromes and the aryl hydrocarbon receptor nuclear translocator. [Regulatory functions, Small molecule interactions].	0.000379044
NC_015276.1\|WP_013661486.1\|2575920_2576313_+\|YraN-family-protein	gnl\|CDD\|237119	PRK12497, PRK12497, YraN family protein.	6.61995e-44

>NC_015276.1|WP_013661483.1|2571768_2572881_+|TfuA-domain-containing-protein
MSSNMIVFAGPSIRKEKILETLPEADVRPPAKQGDVYLATRDKPQVILLIDGFFESVPAVWHKEVLYAMSNGIHVYGSSSMGALRAAELVPFGMVGVGDIFENYASLTFEDDDEVALTHGPAELGFMPISRAMADLRHDLTCAKNNGILTEEHAQAIETHLKSLWYPERNHAALITFANTLLDSRTLTLLESFLKNEAVSLKEQDAEQLIRLAADIDLAHLAPKKVDYTLQENDAWQTLINDVSPTRATRIEVDLPENRSDSIDTDDPLAKFDATLRARALEHAEAIGIEFKPWVRPAFHKVVTKWGCVDEDGQIDFGKVSQKMLALGLSTQQFDRWIEREAMLLAYAYQVEVGNEHIIDATLFAAGESV
>NC_015276.1|WP_013661482.1|2570524_2571769_+|YcaO-like-family-protein
METQQVKAYTTGTHRTVSPKETLEKITPLLLKMGITRLADVTGLDDIGVPVITACRPNAKAISVSQGKGVSVDAAKASAAMEAIETWHAENIDLPTRFCSFNALKENHVVVDLDTLPKMDVKPFNPDERRLWIEAQDLNREHSYYVPYDLAHCDFTLPLPQGSGCFQLSTNGLASGNTVNEAASHALCELIERDAMTLWSFLSSEEQGKRKVDLSTITDPTIGGLLNKLEEADVAVSVWDATSDIGIATFVCTIINKTESQYRPLYSMSGSGTHVDKHVAIMRAITEAVQARLTLISGSRDDASIKIYETRQQMEYQRRIRKELMETPSFVDFNKIDSWIFDTIEEDLELQIAKLAAQGLPCPLFIDLTKTEFDIPVVKVISPGLEGIHDVPGYKFGKRALAFQANVKAVKESL
>NC_015276.1|WP_013661481.1|2569488_2570271_+|hypothetical-protein
MSNCPYEFNEESIQDVFIMRPNGKIAYLPYSVYSDLSRIIESVEVNGDAQRFFLNKDGSYPFNLAGPTVTKVIDWNLQTDEGEPKVHPKQSDVTPQAGYFLDLRRMSMDRLSMIFIGEEPNYPADQAVTDLPRSDSGYQLVPEAFQHQLKETPEQDHLYLAFFNHPNKTRSINQFYSYSVAYITAEELDKWEYSAELLGKLADGHEGLEPNVDFTTKHLETYYGETGVQATALSPMDLEGSPLAMACLTCYVANLRTFKG
>NC_015276.1|WP_013661480.1|2568490_2569276_+|hypothetical-protein
MSNYPYEFNEESIQDVFIMRPNGKIAYLPYSFYSDPSRVIESVEVNGDAQRFFLNEDGSYPFNLAGPAVTKVIDWNLQTENGEPKVHPKQSDIRPQAGYFLDLRRMSIDRLSMIFIGEEPNYPADQAVTDLPRSDSGYQLVPEAFQHQLKETPEQDHLYLAFFNHPNKTRSINQFYSYSVAYITADELTQWEYSAELLGKLADGHEGLEPNVDFTTKHLETYYGETGVQATALSPMDTKGSAFPSQCLLACYIANIRTFKG
>NC_015276.1|WP_013661479.1|2567143_2568301_+|S53-family-peptidase
MEQFTPNTSVTTPFSGSENPFLNSVSQRLKQALSHYHTPKAVADFYQFPENLGEGQTIGVMTLGGAFNPEELNAYCKHFNIDMPEVSIVGTEPVLSEENKKFADLETNMDIQLIAGLTPKAKIVLYYGKDFCDAFQDIIDDKENTPSVINICWAIGEKYLTRKEKETLLSQANQLCERGVTLLAASGDEGIFQSGTTAKRRVPGINLPAGFPNVIACGGTALTPSGIETVWNEAPFSSGGGFSLMTPAPEFQTEALSHYNHCHPEIGTHNIATPDLSANASIEYPSAVMRDGKLAKAWGTSTSAPILTALIARIKTELKNPFGDINALLYQHIGSDVFNSKIEGENGYPSGHKWNPCVGLGSPNGMKLLAAIKQYLSENKVDHNM
>NC_015276.1|WP_013661478.1|2566644_2566944_+|DUF1330-domain-containing-protein
MSVFAVVELTVTDPSWMEKYSENVTPMLLKCGGRYVTATETIDLIEGSDKPQLMGIVEFPSREKAKEFYNSDEYSPYRDARLKGAKCRYLLIDVENGES
>NC_015276.1|WP_013661477.1|2565723_2566464_+|hypothetical-protein
MIENQQQTLNDILESMNDIYIILPDKRVAYLTLDNYKNPDRVVESVSVDGEFIKRVFLNYEGVYPSNLLSPAVTKVIEWNLEDSENLETGYFIDLRKLGMNRVNMVDVLENNSPEADTPIPSQNLPKTDNLFIPVPNEKKYQLRETPQKNNLYIAYFSEPTKTRSDSECYSYKVAYIPHDDIENYIVSETDTVSIQHLKAYYGDTRVQAGSINPLDIGYSPDALAQEVNTSLAFAACYVANLETFK
>NC_015276.1|WP_013661476.1|2561337_2565711_+|protein-kinase
MRQIENNLTTEVNQRFTNISTRFISNAYELLHKIGEGGFGVVYKAVYKRTGQPVAIKFLHISQEKDTGQQARQLARFERESNIVSQLSHAHIVRLLDKGVMDDTTVFSVFEFVEGTSLSDHIKQHGALSINETYDIMLQVLDAIVYAHSQGIIHRDVKPSNIMLNHSGAKLHAKLLDFGISTLTLGQQPEDYRAITITQESLGTPTYCSPEQLRGELTTFSTDLYMWGLVFIECLTGAPAVPGTSVAEIYHQHLNDVPIKIPAPLLDHPLGALLEKTLRKNPKDRIDDAQVLFDDLSSLLVNNLVGKLLPDSSNATSLNSLENTGANNTATLLLRTDDPNFIPSVATQSIERRYMTVLSLTINVLHTDRYDAAEADVVEALFQSTQNQYIDVARRYGGFHVGNLSNQSVFYFGYPVGSDHDARLAARTALEILSLSKRQASYLTKKHGCTFETNCGIHSGIMLKRSNQVPEGFTSHTATQMAQAASNRQILCSADTQAILSPYYNFTENRHAEKNNTAQRHAELTSERVIEAFGFIRGTRNAYPLVGRQTELNQIRASITRPEQYAPEDKALHNTTNTRDTNQAVYIHGDAGVGKSRLIQELRRHESTRSQKIFQCLPEHQNNALYPVLTVIKRHLTQHTLEDSSEYRHLVDTLVDAEFTGSKDEITTLLAIWLNLPDIDNKSLSSLSPAAQKELLFEGLAYLLHENTTLHPLYIFEDIHWADNTTLEFIAALQSTAQQTKQQQSEQTVTQIEQGLGSDNLNSDDLKSASEYDDESKAQHKSESNNENKAEHNDQPSIVITSRNELPAQLNDSSIYPIALAPLDQAATEAFISELFGGADISDAVKNVLLERTDGIPLFIEELATAMRRNNTVRIQNNTVDFTDPDNIDQIPSSLRESIQSKIDHLVYAKDTLQLASSFGRQFSYNLLVAASPYSELQVQNDLDELINNQVIIQQRHVDGDRYLFKHALVRDAGYDSIDTQARPAIHGLIADAIQEHADISDRFVATELAQHYEKAGVPEQACQWYNQAATAAKDTFAIDDAIHLYEAALTNVRRAQINQPLLNAVATDDQHESHNSNTSEALTLKLKDILDGLAACLSRDGQHENARTYLEELNSLLEIDKQYEWLASSLVALGKTYEVIHQHNDALKYYEQALAVLEKAPHSEEPDKSNWWQVWLEIKSAKVYVYYWLVDTEKMHVILIDLEDKLFRLGNHLKLAHFYLNKLQFLYRIKSYAPCDDYIAPSKNAIKYAKSSHCKITLATTVFGLGFSLILCKEYKEAVKNLEIALKQAESNCDKTLTIRCLVYLSIAYRLTGNIHSCRVNAEKAVLVLKSSPMEEYRAVSLANISWCYFRQKKYSDSCHNIKESLIIWNEIGEKIAFPFLWTSHLHAIVLKKYYGDIVYPNQLTELDLAKEILKEKQSKLPEEIVKTLREIITFGEIGLSEIDKIENVTSKHKLI
>NC_015276.1|WP_013661475.1|2560263_2561313_+|FHA-domain-containing-protein
MPDAIKKNTKAGKTNGLDINQNALPISANTFAGGILQSSSGQLIYLRQYHSFGRMQGCHTLLSREDISRIHALICWKNDRWHLEDKSTNGVWINDQKVAKDTPIELHINDKIILSSRDGESFKVLSLLPPCDLLIHINPSKPAIPLNKPQTDINENISMTYGSLGWKFIDRSKGGQPFPIQNGELLQCGGAYYRLQTNIIEHDTLINRPTAHSASDLDFKLEVSDDEEHIKLIIQDAHQTTEVAGHRIQSQLYLLLCLARKSIADKEAGYSDNNRGWIALRQLSKTLGIEPENTRIRLHRLRTRLRDSVSFSGFDACELLQLKDGEIRFNSENITVIKGNDSENRKEHH
>NC_015276.1|WP_013661474.1|2558596_2559373_-|PAS-domain-containing-protein
MKNNGLCVVVLSSFVGFSSSTLLFKGLSSEYGVLALALLIFSFIGLVVCIIRRKKELKELHSVDNDSAMPTRNMFDGIEMLQRFSRKVGSLTRQRDEARRSHKHAEKGRQFAEQILEAVLNNHQIAALLIDRNGKIIEANDSVLTIVGSRREKVIHRNVEFLTCFPFLRDIYKRNWLAELSANGPAILGRSHEGIIYSHNGGISLRCDWEMKEITLDNQRMYLAFIQPSIGQVVKKRFTLVKSSYEPRAKRRPPAQPL
>NC_015276.1|WP_013661484.1|2573212_2574076_-|16S-rRNA-(cytidine(1402)-2'-O)-methyltransferase
MVTQTTPDVRGSFYIVATPIGNLDDISARALKVLENSDFIAAEDTRHSKKLLNHFGIETRLFSVHDHNERDKVDYIKSLLDDGKNIALVSDAGTPLISDPGYHVVNGLRDDGYNVVPVPGPSALITALCASGLPTDQFSFLGFLPAKSKARKDIVSNWVNVPGTVVFYESTHRIIDSVKDINEVHGNQVTLSLARELTKTFETFLHGTPATILDMFAEDSNQTRGEFVVMASLKKDDVDEEEAKANEMLDLLLPEVSVKKASEIVAKFLDLKKNQVYKLALEKSKND
>NC_015276.1|WP_013661485.1|2574110_2575964_+|penicillin-binding-protein-activator
MRSLHSRIIALSTFTLLLVGCGSIETNEDTASAAGSQPEIPLIVEETAPTDPVEFALWRAQNAESIEQSILLYFHAAKEMMAVEEWESAASILNEKVTPFSSSVQFQGYLLLAQANAELQKPLDALSALSRAKRLPIAQTPASENQLGLQRALVLEALENWPATLKERLKLSLTLPPDQRADNQSKLWLAAQNLTNVELDYLRNDNNIILRGWLDVSSLLRDQSLTLEQQLNAFSQWRTSHPSHPASINPPIDFQLIASLGDLIPTSIALMLPMSNELKPASDAILEGFLKTYYATTGLRPKIKVIDTDQYEHVEQAYLDATSDTPDVVIGPLRKSNVARLANTYLSIPTITLNRLENNQSRDNLFYFSLNVADDISELINVAKQAGAEKAAILTTQATWALRQGDEFNAVAEEAAVPVAMNLSYEDTPRGRQNAIKKILLVDESEKRQKMVSKWIGEPIESISRAREDLDYIFFVGKITDAKQIRPLVDFYFADHIPLLSTNSLNDTPPYKLAKKEDIERILFTEIPELLVETNDTGSTDSNLILRLKAMGSDALLLANRYPVFEQLANARLSAKTGIITLDEQGVFHRRPNIVTYRKGKIVDAQTAFKFQGEETQ
>NC_015276.1|WP_013661486.1|2575920_2576313_+|YraN-family-protein
MLKLLSSFKEKKLSKKHSTSGKVAEHLAAEFLERNGLTVIDRNFHSRYGEIDIICKEGEVVVFVEVKFRKNHTRGKAVESITPSKLSKILLTAQYWIKRHKHEHSPVRFDAVTFDKIIDETSLNWLKAII
>NC_015276.1|WP_013661487.1|2576317_2576911_+|SIS-domain-containing-protein
MDLQEAIYTQFAQSFEAQQQALESLPPYIEHAAKVLFGSIASGGKVICIGNGTSAHLSQYFSTLLSDRMDRERPGLPAFSLNADAPTILSITHNDSYHDVFSKQITALGNPGDVLFVIANKGNTSPIIQAIQAAHERKIAIIALTTPDAKNVSSLTSRDDTEIKINLTGTARVQECQITVIHTLVDLLERQLFGYED
>NC_015276.1|WP_013661488.1|2577005_2577788_-|class-II-glutamine-amidotransferase
MCELLGMSANVPTDICFSFSGLRARGGRTGPHKDGWGMAMYRDRQVWSIHDPRPSADSDMAEVMSQTSLKCDIVISHIRQANVGNVCLPNTHPFSRMLWGETWVYAHNGQLEGSDKLALDHYHPIGSTDSERAFCWILGRLAARYGDQRPSLEVLSSFLYELTSGLKQKGVFNMMLSDGDSLFCYCTTKLHWITRRAPFKKATLSDEDVSVDFKEVTTDKDVVTVIATQPLTEDEVWNQMEEGGLCVFNAGEVVFKRNTV
>NC_015276.1|WP_041647905.1|2577780_2579676_-|VWA-domain-containing-protein
MQSLLCGALLLVCSIVFPKAFADTQFRIIVDASGSMVISDPDKLTSEALKLISNLAPEEHATLGVWLFGEEPRVLLPEAPINKETKAKLASYVDNYVTQDLKTDLESIIELLLKTPDTPSLSDGFDRHWILVTDGMVDVSLDKDVNEASRRRIMTTLTEALEKRGIHLHTVSMTGYTDEDMLKQLAVKTNASHTEVASPEELLDTFDRIFAQADPAEELPFEGNTFFIDPSIDEVTLLVFHESSNVTPQLLKPNAVNVPLVSNGSVAVSRTPYYTLVTITSPESGTWEIKNVDIERSSIRIITSLNAQATKISPVVFVNEPVFSTVGLFESNNLIKDPKVLDLMDVTQELSLITGDSRQILEKQPMIQAASQFKNKVEKLTTEGNYSIASKVDGQTFTRKLTQYFSVFPAIKFESANRGENFVAFSATPTNLRLNTLRSNVKLELAYKNGTTEVQEMPFVGQGYWEKVFPIDPESVIRAKAKLIGITQTGIRFEYESEPWTVERKAAGDVTLSKGDQVLSTEALTALATTNREVMPVVVAPQITIVAEEDVETEPDVTEAAETDANAEPEVADSLPETPPEEVATFGMGDWLLYGGLNLLAVILIGGGYFVYRRIKRNKQNTEEIEVEDDV
>NC_015276.1|WP_013661490.1|2579799_2580279_-|YcgN-family-cysteine-cluster-protein
MIAKRYEPFWKTTTLEDMESDQWESICDGCGKCCLQKLQDDETDEVYYTDLSCHQLDIAKCQCKVYETRELLVESCLTLKVEDIPEFHWLPDTCSYRVLSETGDLPNWHPLVVGDDKEMQRQGLKVSHYAVSESKVDEEDWDTHIIRWVHGMPESYDPF
>NC_015276.1|WP_013661491.1|2580278_2580569_-|YcgL-domain-containing-protein
MSRIIIEIFRSSKKDEMYLYVEKSKGLTEIPEALMERFGKGISAMTMLLTEESKLARADASAVMKAIQEQGFYLQLPPVRDDYLLDLYKTPTEAAY
>NC_015276.1|WP_013661492.1|2580583_2581735_-|ribonuclease-D
MTIVDQSYDIVWVETDAELASWCEYWSTLNVIAVDTEFLRRTTYYPITGLIQISEGEKAVLIDPQTITEWAPLKDLMVNLDVMKVFHACSEDLDVFDRLLGVLPTPFYDTQIGEAYANGQWSVSYVKLIQAYLSIEVAKDETRSDWTVRPLTEAQKRYAALDVVYLAKVYPQQIEMLQKKNMLDWALEDCDTLKWQYMQNGDPEQNWSNVKAAWRLSPKSLTLLRMLFIWREEQAKSEDVPKGQVLKDRSLWAIAKFMPDHHKAISKTEDLTGKQHRLYGDTILEKVKVIKSLSEDEYQLMLPMPLPSQAGELSKSIKSYIRKRSEELGVAPEAVMKRKLLDPIVRHLYEGGELDWSNPAMVGWRKDTIIEPILSNFGEQSSN
>NC_015276.1|WP_013661493.1|2581736_2582330_-|recombination-protein-RecR
MFSPLIKELMESLRCLPGVGPKSAQKMALYLLERDSQGADRLANALRDALDKVGRCATCRTLTEDTECSICLDQARDGTRLCIVETPADVIAMENAGSFDGRYFVLLGHLSPIDGIGPEELGLDRLENLVRNTDVEEVIIATNSTIEGEATSHYISELLKPLNIELSRLAQGVPMGGELEYVDGNTLALALKGRKKL

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Crispr_ID: NC_015276_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_6

3643810-3646958

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCTGCGTGTACGGCAGCGAAC	PILER-CR
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CRISPRCasFinder
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CRT

52 spacers

cas6f,cas7f,cas5f,cas8f,cas3f,cas1,WYL

The CRISPR arrays of NC_015276_6

>merge|NC_015276|6|3643810-3646958|PILER-CR,CRISPRCasFinder,CRT
TTTCTAAGCTGCGTGTGCGGCAGCGAACGCGAGGCTTAGGCATAAAAAACCGCTGATGCTTTCTAAGCTGCGTGTACGGCAGCAAACATAAAAGCAGAGTACGAAAACGCCAGAAGTCGATTTCTAAGCTGCGTGTGCGGCAGCGAACGGGCAGATTACTGCATACATCGAACAGCTTCTTTCTAAGCTGCGCGTACGGCAGCGAACAAGTTTTTTCAGAGTGTTGAATGCTGTTTGCTTTTCTAAGCTGCGTGTACGGCAACGAACCCGCTCAAGCGGAATCTGAACACCACAATCTATTTCTAAGCTGCGTGTACGGCAGCGAACCTCTCGCTTGCGAGGCGGCGGGAGCATGGCGCTTTCTAAGCTGCGTGTGCGGCAGCGAACAGATAGGGCATAGATAATTTCGGCCATCTGGTTTTCTAAGCTGCGTGTACGGCAGCGAACCCGTTACAAACACGGATTACGGCGCGATTGAGTTTCTAAGCTGCGTGTACGGCAGCGAACTGGTTCACCATCCCCTACTTCACCTTCAAAATTTTCTAAGCTGCGTGTACGGCAGCGAACTTCCCCTGTCAAAACACAAACAACGTTCACAATTTCTAAGCTGCGTGTACGGCAGCGAACCGCCCATATTGCCTTGTCTGCGTTTTTTCTAAGTTTCTAAGCTGCGTGTACGGCAGCGAACATAGTTTCCGTTTATGTTCACTCCCTTCGGCAATTTCTAAGCTGCGTGTACGGCAGCGAACATAGGCTGAATCTGTTCTAGTAATTGTGCGGATTTCTAAGCTGCGTGTACGGCAGCGAACTTCAACCCATTTACCTCATAGCGAGCGTTACGTTTCTAAGCTGCGTGTACGGCAGCGAACTTTAAAGGAGCTTTACTAGCCCCTCTTATAAATTTCTAAGCTGCGTGTACGGCAGCGAACGTCTTCACCTAGTTGAGTTACCTTATCTTCTATTTCTAAGCTGCGTGTACGGCAGCGAACATGCTAGCTCACTTTCCTTATGTAGACACATATTTCTAAGCTGCGTGTACGGCAGCGAACGTGTTGTTACTCTTTAAACCGCTTATCATTAATTTCTAAGCTGCGTGTACGGCAGCGAACCTCGCCTTTAAGAGCGTTAACGCCTTCAACTATTTCTAAGCTGCGTGTACGGCAGCGAACTCGTGCACACGAGCATACTGGAATATCTCAGATTTCTAAGCTGCGTGTACGGCAGCGAACTAAAAGTTTGGACTGTAACTTGCCCACATTGTTTTCTAAGCTGCGTGTACGGCAGCGAACAGAGTTTTTGAACTTTAACGGCTCTACGTTATTTTCTAAGCTGCGTGTACGGCAGCGAACTACATCCCCACCCCCGGGATACATGCTTGTTATTTCTAAGCTGCGTGTACGGCAGCGAACTCTACCATAACAAAATCCTCTTATATCGTTATTTTCTAAGCTGCGTGTACGGCAGCGAACGAAGATATAAGGGCAAGCTTTGGTAGTGTTGCTTTCTAAGCTGCGTGTACGGCAGCGAACTGGCGCGTCTTAACGCTACGACTAACGCGTCGTTTCTAAGCTGCGTGTACGGCAGCGAACAAGAGCTAGAGCAGAGAATCGAGGGAGTGGGTTTTCTAAGCTGCGTGTACGGCAGCGAACCAAGGGGAACAAATGAATCAAACGATTAACAATTTCTAAGCTGCGTGTACGGCAGCGAACATACGAGGTGGAGGGCGCAACGATCCCGACAATTTCTAAGCTGCGTGTACGGCAGCGAACTGGATTTGCTTGCTCAAGTGGCGGGGCTTGGCTTTCTAAGCTGCGTGTACGGCAGCGAACAATTTATTACCTTTTTTAGCGTTTACCTCTTCTTTCTAAGTTGCGTGTACGGCAGCGAACTCAGAAGACAACGTGTACACGCTGTATAAGGATTTCTAAGCTGCGTGTACGGCAGCGAACAACAGTGGAAACAGGAACCCCAATGGCTCTAATTTCTAAGCTGCGTGTACGGCAGCGAACCTCTTGCTTGCTATTTTTCATAGTCTCGCTAATTTCTAAGCTGCGTGTACGGCAGCGAACAGGGACTTGCGTTATTTGGGATTTGGAATGAATTTCTAAGCTGCGTGTACGGCAGCGAACTGGGTGGGGGTGTAAAGAACCTTTATGCCAAATTTCTAAGCTGCGTGTACGGCAGCGAACTGGGTGGGGGTGTAAAGAACCTTTATGCCAAATTTCTAAGCTGCGTGTACGGCAGCGAACAAGAGCGTGCGATATGTTTAAGAATCGGGTCATTTCTAAGCTGCGTGTACGGCAGCGAACCCCAGCAAAAACGCTTCATTCGCTTTTTGTTGTTTCTAAGCTGCGTGTACGGCAGCGAACCAAACATACACTTATGAACCAGATGATGATGATTTCTAAGCTGCGTGTACGGCAGCGAACATTTTGGCCTGTATTGCTGTTTCAATGTCGGGTTTCTAAGCTGCGTGTACGGCAGCGAACTCACTGCGTTAATGTAAACCCTTGCATCTTCTTTTCTAAGCTGCGTGTACGGCAGCGAACATTCATATGATACCTAGAGTTGACAGAGTGGATTTCTAAGCTGCGTGTACGGCAGCGAACGGTTACCTCCCAGAGGCACAGTTTACGACATTTTTCTAAGCTGCGTGTACGGCAGCGAACCCTCTCTTAACTCATTACAAACATCTTGTGAATTTCTAAGCTGCGTGTACGGCAGCGAACCTCCTCTATCATATCCGCTAGAGCATCTTATATTTCTAAGCTGCGTGTACGGCAGCGAACGACAATTTATCTATAAAAGAGATTGACAAGAATTTCTAAGCTGCGTGTACGGCAGCGAACTAAGACACCCCTTCGGATAGTTGCGGCATAGCTTTCTAAGCTGCGTGTACGGCAGCGAACACACTAGGGAAAAAGTAGAAGCACATTATTTATTTCTAAGCTGCGTGTACGGCAGCGAACATTAGCAGAATCGAAGCACATCCCGTACATTATTTCTAAGCTGCGTGTACGGCAGCGAACCGTACTAAGCGTATGCTAAGAAACAACTTAAATTTCTAAGCTGCGTGTACGGCAGCGAACTTATGCTTTGCTGTGAATGGATTCATGGATGCTTTCTAAGCTGCGTGTACGGCAGCGAAC

>NC_015276|6|7|3643810-3646958|PILER-CR
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCGAGGCTTAGGCATAAAAAACCGCTGATGC
TTTCTAAGCTGCGTGTACGGCAGCAAAC	ATAAAAGCAGAGTACGAAAACGCCAGAAGTCGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GGGCAGATTACTGCATACATCGAACAGCTTC
TTTCTAAGCTGCGCGTACGGCAGCGAAC	AAGTTTTTTCAGAGTGTTGAATGCTGTTTGCT
TTTCTAAGCTGCGTGTACGGCAACGAAC	CCGCTCAAGCGGAATCTGAACACCACAATCTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCTCGCTTGCGAGGCGGCGGGAGCATGGCGC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGATAGGGCATAGATAATTTCGGCCATCTGGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCGTTACAAACACGGATTACGGCGCGATTGAG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGTTCACCATCCCCTACTTCACCTTCAAAAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTCCCCTGTCAAAACACAAACAACGTTCACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CGCCCATATTGCCTTGTCTGCGTTTTTTCTAAG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATAGTTTCCGTTTATGTTCACTCCCTTCGGCAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATAGGCTGAATCTGTTCTAGTAATTGTGCGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTCAACCCATTTACCTCATAGCGAGCGTTACG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTTAAAGGAGCTTTACTAGCCCCTCTTATAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GTCTTCACCTAGTTGAGTTACCTTATCTTCTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATGCTAGCTCACTTTCCTTATGTAGACACATA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GTGTTGTTACTCTTTAAACCGCTTATCATTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCGCCTTTAAGAGCGTTAACGCCTTCAACTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCGTGCACACGAGCATACTGGAATATCTCAGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TAAAAGTTTGGACTGTAACTTGCCCACATTGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AGAGTTTTTGAACTTTAACGGCTCTACGTTAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TACATCCCCACCCCCGGGATACATGCTTGTTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCTACCATAACAAAATCCTCTTATATCGTTAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GAAGATATAAGGGCAAGCTTTGGTAGTGTTGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGCGCGTCTTAACGCTACGACTAACGCGTCG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AAGAGCTAGAGCAGAGAATCGAGGGAGTGGGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CAAGGGGAACAAATGAATCAAACGATTAACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATACGAGGTGGAGGGCGCAACGATCCCGACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGATTTGCTTGCTCAAGTGGCGGGGCTTGGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AATTTATTACCTTTTTTAGCGTTTACCTCTTC
TTTCTAAGTTGCGTGTACGGCAGCGAAC	TCAGAAGACAACGTGTACACGCTGTATAAGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AACAGTGGAAACAGGAACCCCAATGGCTCTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCTTGCTTGCTATTTTTCATAGTCTCGCTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AGGGACTTGCGTTATTTGGGATTTGGAATGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGGTGGGGGTGTAAAGAACCTTTATGCCAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGGTGGGGGTGTAAAGAACCTTTATGCCAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AAGAGCGTGCGATATGTTTAAGAATCGGGTCA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCCAGCAAAAACGCTTCATTCGCTTTTTGTTG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CAAACATACACTTATGAACCAGATGATGATGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTTTGGCCTGTATTGCTGTTTCAATGTCGGG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCACTGCGTTAATGTAAACCCTTGCATCTTCT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTCATATGATACCTAGAGTTGACAGAGTGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GGTTACCTCCCAGAGGCACAGTTTACGACATT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCTCTCTTAACTCATTACAAACATCTTGTGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCCTCTATCATATCCGCTAGAGCATCTTATA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GACAATTTATCTATAAAAGAGATTGACAAGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TAAGACACCCCTTCGGATAGTTGCGGCATAGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ACACTAGGGAAAAAGTAGAAGCACATTATTTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTAGCAGAATCGAAGCACATCCCGTACATTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CGTACTAAGCGTATGCTAAGAAACAACTTAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTATGCTTTGCTGTGAATGGATTCATGGATGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC

>NC_015276|6|5|3643810-3646958|CRISPRCasFinder
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCGAGGCTTAGGCATAAAAAACCGCTGATGC
TTTCTAAGCTGCGTGTACGGCAGCAAAC	ATAAAAGCAGAGTACGAAAACGCCAGAAGTCGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GGGCAGATTACTGCATACATCGAACAGCTTC
TTTCTAAGCTGCGCGTACGGCAGCGAAC	AAGTTTTTTCAGAGTGTTGAATGCTGTTTGCT
TTTCTAAGCTGCGTGTACGGCAACGAAC	CCGCTCAAGCGGAATCTGAACACCACAATCTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCTCGCTTGCGAGGCGGCGGGAGCATGGCGC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGATAGGGCATAGATAATTTCGGCCATCTGGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCGTTACAAACACGGATTACGGCGCGATTGAG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGTTCACCATCCCCTACTTCACCTTCAAAAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTCCCCTGTCAAAACACAAACAACGTTCACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CGCCCATATTGCCTTGTCTGCGTTTTTTCTAAG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATAGTTTCCGTTTATGTTCACTCCCTTCGGCAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATAGGCTGAATCTGTTCTAGTAATTGTGCGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTCAACCCATTTACCTCATAGCGAGCGTTACG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTTAAAGGAGCTTTACTAGCCCCTCTTATAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GTCTTCACCTAGTTGAGTTACCTTATCTTCTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATGCTAGCTCACTTTCCTTATGTAGACACATA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GTGTTGTTACTCTTTAAACCGCTTATCATTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCGCCTTTAAGAGCGTTAACGCCTTCAACTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCGTGCACACGAGCATACTGGAATATCTCAGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TAAAAGTTTGGACTGTAACTTGCCCACATTGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AGAGTTTTTGAACTTTAACGGCTCTACGTTAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TACATCCCCACCCCCGGGATACATGCTTGTTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCTACCATAACAAAATCCTCTTATATCGTTAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GAAGATATAAGGGCAAGCTTTGGTAGTGTTGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGCGCGTCTTAACGCTACGACTAACGCGTCG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AAGAGCTAGAGCAGAGAATCGAGGGAGTGGGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CAAGGGGAACAAATGAATCAAACGATTAACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATACGAGGTGGAGGGCGCAACGATCCCGACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGATTTGCTTGCTCAAGTGGCGGGGCTTGGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AATTTATTACCTTTTTTAGCGTTTACCTCTTC
TTTCTAAGTTGCGTGTACGGCAGCGAAC	TCAGAAGACAACGTGTACACGCTGTATAAGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AACAGTGGAAACAGGAACCCCAATGGCTCTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCTTGCTTGCTATTTTTCATAGTCTCGCTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AGGGACTTGCGTTATTTGGGATTTGGAATGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGGTGGGGGTGTAAAGAACCTTTATGCCAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGGTGGGGGTGTAAAGAACCTTTATGCCAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AAGAGCGTGCGATATGTTTAAGAATCGGGTCA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCCAGCAAAAACGCTTCATTCGCTTTTTGTTG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CAAACATACACTTATGAACCAGATGATGATGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTTTGGCCTGTATTGCTGTTTCAATGTCGGG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCACTGCGTTAATGTAAACCCTTGCATCTTCT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTCATATGATACCTAGAGTTGACAGAGTGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GGTTACCTCCCAGAGGCACAGTTTACGACATT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCTCTCTTAACTCATTACAAACATCTTGTGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCCTCTATCATATCCGCTAGAGCATCTTATA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GACAATTTATCTATAAAAGAGATTGACAAGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TAAGACACCCCTTCGGATAGTTGCGGCATAGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ACACTAGGGAAAAAGTAGAAGCACATTATTTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTAGCAGAATCGAAGCACATCCCGTACATTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CGTACTAAGCGTATGCTAAGAAACAACTTAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTATGCTTTGCTGTGAATGGATTCATGGATGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC

>NC_015276|6|3|3643810-3646958|CRT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCGAGGCTTAGGCATAAAAAACCGCTGATGC
TTTCTAAGCTGCGTGTACGGCAGCAAAC	ATAAAAGCAGAGTACGAAAACGCCAGAAGTCGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GGGCAGATTACTGCATACATCGAACAGCTTC
TTTCTAAGCTGCGCGTACGGCAGCGAAC	AAGTTTTTTCAGAGTGTTGAATGCTGTTTGCT
TTTCTAAGCTGCGTGTACGGCAACGAAC	CCGCTCAAGCGGAATCTGAACACCACAATCTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCTCGCTTGCGAGGCGGCGGGAGCATGGCGC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGATAGGGCATAGATAATTTCGGCCATCTGGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCGTTACAAACACGGATTACGGCGCGATTGAG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGTTCACCATCCCCTACTTCACCTTCAAAAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTCCCCTGTCAAAACACAAACAACGTTCACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CGCCCATATTGCCTTGTCTGCGTTTTTTCTAAG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATAGTTTCCGTTTATGTTCACTCCCTTCGGCAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATAGGCTGAATCTGTTCTAGTAATTGTGCGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTCAACCCATTTACCTCATAGCGAGCGTTACG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTTAAAGGAGCTTTACTAGCCCCTCTTATAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GTCTTCACCTAGTTGAGTTACCTTATCTTCTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATGCTAGCTCACTTTCCTTATGTAGACACATA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GTGTTGTTACTCTTTAAACCGCTTATCATTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCGCCTTTAAGAGCGTTAACGCCTTCAACTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCGTGCACACGAGCATACTGGAATATCTCAGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TAAAAGTTTGGACTGTAACTTGCCCACATTGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AGAGTTTTTGAACTTTAACGGCTCTACGTTAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TACATCCCCACCCCCGGGATACATGCTTGTTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCTACCATAACAAAATCCTCTTATATCGTTAT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GAAGATATAAGGGCAAGCTTTGGTAGTGTTGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGCGCGTCTTAACGCTACGACTAACGCGTCG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AAGAGCTAGAGCAGAGAATCGAGGGAGTGGGT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CAAGGGGAACAAATGAATCAAACGATTAACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATACGAGGTGGAGGGCGCAACGATCCCGACAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGATTTGCTTGCTCAAGTGGCGGGGCTTGGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AATTTATTACCTTTTTTAGCGTTTACCTCTTC
TTTCTAAGTTGCGTGTACGGCAGCGAAC	TCAGAAGACAACGTGTACACGCTGTATAAGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AACAGTGGAAACAGGAACCCCAATGGCTCTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCTTGCTTGCTATTTTTCATAGTCTCGCTAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AGGGACTTGCGTTATTTGGGATTTGGAATGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGGTGGGGGTGTAAAGAACCTTTATGCCAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TGGGTGGGGGTGTAAAGAACCTTTATGCCAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	AAGAGCGTGCGATATGTTTAAGAATCGGGTCA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCCAGCAAAAACGCTTCATTCGCTTTTTGTTG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CAAACATACACTTATGAACCAGATGATGATGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTTTGGCCTGTATTGCTGTTTCAATGTCGGG
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TCACTGCGTTAATGTAAACCCTTGCATCTTCT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTCATATGATACCTAGAGTTGACAGAGTGGA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GGTTACCTCCCAGAGGCACAGTTTACGACATT
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CCTCTCTTAACTCATTACAAACATCTTGTGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CTCCTCTATCATATCCGCTAGAGCATCTTATA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	GACAATTTATCTATAAAAGAGATTGACAAGAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TAAGACACCCCTTCGGATAGTTGCGGCATAGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ACACTAGGGAAAAAGTAGAAGCACATTATTTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	ATTAGCAGAATCGAAGCACATCCCGTACATTA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	CGTACTAAGCGTATGCTAAGAAACAACTTAAA
TTTCTAAGCTGCGTGTACGGCAGCGAAC	TTATGCTTTGCTGTGAATGGATTCATGGATGC
TTTCTAAGCTGCGTGTACGGCAGCGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013662449.1\|3658384_3659581_+\|aspartate/tyrosine/aromatic-aminotransferase	unknown	unknown	gnl\|CDD\|181731
NC_015276.1\|WP_013662441.1\|3647708_3648746_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|378222
NC_015276.1\|WP_013662435.1\|3639000_3639687_+\|DUF480-domain-containing-protein	unknown	unknown	gnl\|CDD\|377312
NC_015276.1\|WP_013662438.1\|3641807_3642710_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176122
NC_015276.1\|WP_013662442.1\|3648787_3649783_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	pfam09614_cas5f_CAS-I-F	gnl\|CDD\|378221
NC_015276.1\|WP_041647967.1\|3649779_3651060_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	cd09735_cas8f_CAS-I-F	gnl\|CDD\|378220
NC_015276.1\|WP_013662444.1\|3651049_3651217_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662445.1\|3651445_3654820_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3f	cd09673_cas3f_CAS-I-F	gnl\|CDD\|274201
NC_015276.1\|WP_041648875.1\|3657011_3658193_-\|methyltransferase	unknown	unknown	gnl\|CDD\|379330
NC_015276.1\|WP_013662433.1\|3637707_3638157_+\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|378058
NC_015276.1\|WP_013662430.1\|3634432_3635365_-\|choline-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|188316
NC_015276.1\|WP_013662447.1\|3655922_3656786_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NC_015276.1\|WP_013662446.1\|3654816_3655794_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
NC_015276.1\|WP_013662436.1\|3639724_3640768_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_015276.1\|WP_013662439.1\|3642865_3643564_+\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NC_015276.1\|WP_013662437.1\|3640799_3641738_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NC_015276.1\|WP_013662440.1\|3647087_3647693_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	pfam09618_cas6f_CAS-I-F	gnl\|CDD\|378224
NC_015276.1\|WP_013662432.1\|3636454_3637651_+\|putative-C-S-lyase	unknown	unknown	gnl\|CDD\|275146
NC_015276.1\|WP_013662431.1\|3635431_3636013_-\|transcriptional-regulator-BetI	unknown	unknown	gnl\|CDD\|179115
NC_015276.1\|WP_013662434.1\|3638192_3638996_+\|sterol-desaturase-family-protein	unknown	unknown	gnl\|CDD\|225546

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013662449.1\|3658384_3659581_+\|aspartate/tyrosine/aromatic-aminotransferase	gnl\|CDD\|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
NC_015276.1\|WP_013662441.1\|3647708_3648746_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NC_015276.1\|WP_013662435.1\|3639000_3639687_+\|DUF480-domain-containing-protein	gnl\|CDD\|377312	pfam04337, DUF480, Protein of unknown function, DUF480. This family consists of several proteins of uncharacterized function.	4.91438e-81
NC_015276.1\|WP_013662438.1\|3641807_3642710_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.43525e-77
NC_015276.1\|WP_013662442.1\|3648787_3649783_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	3.64942e-148
NC_015276.1\|WP_041647967.1\|3649779_3651060_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|378220	pfam09611, Cas_Csy1, CRISPR-associated protein (Cas_Csy1). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	2.83027e-156
NC_015276.1\|WP_013662445.1\|3651445_3654820_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|274201	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST. The helicase in many CRISPR-associated (cas) gene clusters is designated Cas3, and most Cas3 proteins are described by model TIGR01587. Members of this family are considerably larger, show a number of motifs in common with TIGR01587 sequences, and replace Cas3 in some CRISPR/cas loci in a number of Proteobacteria, including Yersinia pestis, Chromobacterium violaceum, Erwinia carotovora subsp. atroseptica SCRI1043, Photorhabdus luminescens subsp. laumondii TTO1, Legionella pneumophila, etc.	0
NC_015276.1\|WP_041648875.1\|3657011_3658193_-\|methyltransferase	gnl\|CDD\|379330	pfam13679, Methyltransf_32, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.72287e-20
NC_015276.1\|WP_013662433.1\|3637707_3638157_+\|DUF1801-domain-containing-protein	gnl\|CDD\|378058	pfam08818, DUF1801, Domain of unknown function (DU1801). This large family of bacterial proteins is uncharacterized. They contain a presumed domain about 110 amino acids in length.	7.84055e-08
NC_015276.1\|WP_013662430.1\|3634432_3635365_-\|choline-ABC-transporter-substrate-binding-protein	gnl\|CDD\|188316	TIGR03414, ABC_choline_bnd, choline ABC transporter, periplasmic binding protein. Partial phylogenetic profiling () vs. the genome property of glycine betaine biosynthesis from choline consistently reveals a member of this ABC transporter periplasmic binding protein as the best match, save for the betaine biosynthesis enzymes themselves. Genomes often carry several paralogs, one encoded together with the permease and ATP-binding components and another encoded next to a choline-sulfatase gene, suggesting that different members of this protein family interact with shared components and give some flexibility in substrate. Of two members from Sinorhizobium meliloti 1021, one designated ChoX has been shown experimentally to bind choline (though not various related compounds such as betaine) and to be required for about 60 % of choline uptake. Members of this protein have an invariant Cys residue near the N-terminus and likely are lipoproteins. [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_015276.1\|WP_013662447.1\|3655922_3656786_-\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	3.406e-07
NC_015276.1\|WP_013662446.1\|3654816_3655794_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	1.67292e-172
NC_015276.1\|WP_013662436.1\|3639724_3640768_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.40048e-59
NC_015276.1\|WP_013662439.1\|3642865_3643564_+\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	2.66299e-72
NC_015276.1\|WP_013662437.1\|3640799_3641738_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	9.56632e-39
NC_015276.1\|WP_013662440.1\|3647087_3647693_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	7.5384e-71
NC_015276.1\|WP_013662432.1\|3636454_3637651_+\|putative-C-S-lyase	gnl\|CDD\|275146	TIGR04350, aminotransferase_class_I_and_II, putative C-S lyase. Members of this subfamily are probable C-S lyases from a family of pyridoxal phosphate-dependent enzymes that tend to be (mis)annotated as probable aminotransferases. One member is PatB of Bacillus subtilis, a proven C-S-lyase. Another is the virulence factor cystalysin from Treponema denticola, whose hemolysin activity may stem from H2S production. Members of the seed alignment occur next to examples of the enzyme 5-histidylcysteine sulfoxide synthase, from ovothiol A biosynthesis, and would be expected to perform a C-S cleavage of 5-histidylcysteine sulfoxide to leave 1-methyl-4-mercaptohistidine (ovothiol A).	4.2161e-149
NC_015276.1\|WP_013662431.1\|3635431_3636013_-\|transcriptional-regulator-BetI	gnl\|CDD\|179115	PRK00767, PRK00767, transcriptional regulator BetI; Validated.	4.34144e-76
NC_015276.1\|WP_013662434.1\|3638192_3638996_+\|sterol-desaturase-family-protein	gnl\|CDD\|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	1.24392e-37

>NC_015276.1|WP_013662439.1|3642865_3643564_+|pirin-family-protein
MITLRNANDRGHANFGWLDSYHTFSFGSYYDPAHMGFSHLRVINDDTVAPSAGFDTHGHRDMEIISLVTQGRIAHKDSVGNIKELPKGEYQLMSAGAGIYHSEFNAKDDETLKFLQIWIQPNKQGGKPGYQQKAFGEDAGITPIITPTGEHGTLAIKQDMQLMQVILEKGQTETVNANSERRYYVHQIEGELTLNNGTTLRPGDGAMIQSEDTLTLQNDQEQRVKAILFDLV
>NC_015276.1|WP_013662438.1|3641807_3642710_-|LysR-family-transcriptional-regulator
MHNAITLDNLRVVEAIRQSGSFAGAAQVLHKVPSALTYTVTKLEDDLGLLLFERSKKGARLTAAGTLVLEQGRPILEAVARLEESMRAFEAGWEPCLRIAHDVILSTGPLLQVIGEFLDRELPVEVVYDSVAVGGGWDSLISEQCDIAVGVSGDFPKGEFEVKAIGTFSFLFAIAPTHPLALLDRPVSAQDLREYPSIVVSDSSRVLPKISSGIFESKQTVKVPDMASKIAAQCMGLGVGYLPTHLVQDKLKDGSLVERECEIPRADMTAYIAWRKAKKGKGLRWFVEHLSAADWGLCRD
>NC_015276.1|WP_013662437.1|3640799_3641738_-|AEC-family-transporter
MTIILAVLPVFLLLVLGVFLRRIRFLPDDTWVGFDRLVYWVLFPALLFNKTSQIDLYSPMIPTYATLLLGALVVTAAVSFLGGFLLKLAPPQNSSLLQASVRYNTFITLAIAQQLYGSEGLVLATIGAAVLIPTINVFLVISMVLMHGDRNASVIRLVVKELFRNPLVLSIATGLSVNALGWSPVLILTNVTEILSQATLPLVLLAVGASVRLDAVKDVGKAFVWGSVSRMLVFPAVIFALCVQLDISGLPAAIALLFGFSPTATSAYALARQLGGDAPQMAAHITLQTGLCLVTIPLSIALTQWWMEGAFS
>NC_015276.1|WP_013662436.1|3639724_3640768_+|Gfo/Idh/MocA-family-oxidoreductase
MNEVRWGILGTGNIARTFANDFRHAKTGTLKAVASRNKDNADSFANDHDIELAMVDYYSLINSQEVDVVYIATPHSTHYELARAAILSGKAVLCEKPFTLNEAQAKELFELAEAHQVFMMEAMWTRFIPALEQAIEWIEEGEIGELLGIQASFNFKGPTDPEHRLLNPELGGGALLDVGIYPIFLAQLFLGRPDFVQNQVVIGDTDVDLFEQIMLGWESGQLASLEASILSPAPNRATLTGTQGYIEFGPEWYKSKSVRLIKADNSERAVEFDYEGEGYQFEVEEVNRCLIEGLLQSPNHSWQNTLNQLSTMDEIRQDMGVIYPEDGTSLDQDELDHHHHEHHHHKH
>NC_015276.1|WP_013662435.1|3639000_3639687_+|DUF480-domain-containing-protein
MSYYELNPMEARVIGCLIEKSITTPEQYPLSLNALVNACNQKSSRDPVVNYSELDVQDTIETLVERALITEVTLGSRVAKYQHRFCNTEFSDLQFSAGETAVVCLQLLRGAQTPGEIRSRSGRLHTFSSLHEVDEALANLKEMTGGPFIEMLPKEPGRRERRFQSTLCLEREAIDASLHEAESTTSTTQSNNATRPSLPDAIKRIDELESKLAELTERLETLEQADRL
>NC_015276.1|WP_013662434.1|3638192_3638996_+|sterol-desaturase-family-protein
MTDYTLRVIVFFAVFAALIVWQWRSPRSTLQKWRYRWRHNLLLFSSGVLVVRVAQPTLLSLVAYSYNEGLLTYIDLPSTISVFVGIVLLDVAIYWQHRVFHTVPLLWRLHRVHHTDPELDISSAVRFHPLEILLSLCIKSAVIVVLGIPALSVLLFDILLNAASLFNHTNARLPKKIEKIVRLIIVTPDHHRIHHSRDINEANSNYAFFLSIWDKIFDSYTHSAKQGDLQIAIGLPQTKQYEPKGILSLFTMPFWTHSRTTKEVKGD
>NC_015276.1|WP_013662433.1|3637707_3638157_+|DUF1801-domain-containing-protein
MHGKSTSVEASQTIDTPTIAGDEIEVTNYISEAAPEVRSDLSQLIGLIQLIAPEATLHLERGVPVFYLGQHWTFSVIAHQKRVSLIFDDFDIQDEGFSFRERLKKASFGDHCISFKKLNEGNLNVIAELLGKLKVDTLRKYPLQKKSIH
>NC_015276.1|WP_013662432.1|3636454_3637651_+|putative-C-S-lyase
MDKSVFDKVIDRTHMSSAKWNRYSDDVIPMWVADMDFDSPNCIKTAIQKRVEEGVLGYTMIPESLKSILVNHCQNAYDWQVEANHLIHLPGLVCALHLAARALTSEDDSIIVPGPVYYHLTKAPELANRHLESVPLLIENSVESITEKAIDNMSEKDRWVIDKEKFETACAAKNAKMIMLCNPHNPGGTVYRREELEEIHALAKKYDLIIVSDEIHCDLILDDQKHIPIASLNEDAAQRTITLMSPSKTYNVAGLGYAFAVIANNQLRTQFNKARQSVVPDPNLLGLVAAEAAYKDGEAWRQELLAYLRKNREFIKNSLKDLPLKMASSEATYLAWIDASELNLDDPYRFFLEAGVATSSGSDFGNSQFIRLNFGCPTSIIEQAMMRISKAISTLDKT
>NC_015276.1|WP_013662431.1|3635431_3636013_-|transcriptional-regulator-BetI
MPKVGMPEIRKPQLVQAAIQAIDKYGFSGATVGVISKKAGVSPAIINHYFGGKNGLFEETMKTLIREFFEILSQERELVKNSTTKEKVMSVVRASINQAQTKPEIVKVWMGFWASSMHSPSLYRLQNVYARRLQTTLVIVLKEAFEGEEARNIAATVAAMIDGMWLRGSLAGDLDCDKAAGHIRDYLDLVFER
>NC_015276.1|WP_013662430.1|3634432_3635365_-|choline-ABC-transporter-substrate-binding-protein
MFKKVTKTALAVALAGSASLSMADCSTVRFSDVGWTDITATTAVTSAVLEGLGYKTKTQLLSVPVTYSSLANNDIDVFLGNWMPTMTADITPYLEAGTVEDLGPNLNGAKYTLAVNKAAYDAGVKDFADLAENRRKFSGRIYGIEPGNDGNRLIQDMIDTNAFDLGDFQVVESSEAGMLSQVSRSVRRNKWIVFLGWAPHPMNANFEMEYLSGGDDYFGPNFGGSSVHTNVRKGYVQECSNVGALLTNLKFTLDMENEIMGSILDKGESPEAAATSWLKANPAALDSWLEGVSTLSGGEGLPAVKSHLGL
>NC_015276.1|WP_013662440.1|3647087_3647693_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MNYYQDITLLPSDDIGMHFLWSKVMMQLHLALVEIQDANQKAPVASSFPNYREAAQNKPAYVGNKIRLFATNKADLERLNIQKWMNRLEDYLHIKSISEVDPSKVQGYESFSRLRKPGNVDYMIRRRMKGLDKSHEEASDYFKDYKVSDNFKRLPFIQMKSLQKDREFRLVVKRKTLEQAVETDFVFNTYGLNKDVALPKF
>NC_015276.1|WP_013662441.1|3647708_3648746_-|type-I-F-CRISPR-associated-protein-Csy3
MAKKDNNIASVLAFEKKLVPSDGYLYGTSWESRKDSSQVKPLNLQEKSVRGTISNRLKAAVKNDPAKLNAEVEKANLQRVDACSLGTDQDTLNLQFTLKVLGGIFKPSACNNALFKQSYETAAKAYIETHSFKELARRYAINLANGRFLWRNRVGAEQIEIIISARNGETNEEFTFNAFDFSTRHFDTTTADIDALAALIAKALASEDGFLLLDVNCFVQMGRAQEVYPSEELVLDKGKGEKSKILYHVGGVAAMHSQKLGNALRTIDTWYAEFQDSDLSVGPIAIEPYGAVTNLGKAFRTPKDKQDFYSFFDVWARGEQLSREEDEHYVMATLVRGGVFGESDK
>NC_015276.1|WP_013662442.1|3648787_3649783_-|type-I-F-CRISPR-associated-protein-Csy2
MSDVKKLLMLPHIQVHNANALSSPYTIGFPAMTAWLGAVHALQRRLNQHGIGVRFEAVGVVSHDVNLQTYKGTNDFVSSIIGTGNPLDKSGERSSFIEEARCHLEVSLVIECSHIEIEDQEQALAAIVHLLNGSMKLAGGDIQKFTQPYFMVVEEGDDENMRRFKRALMPGYALIERRDLIVEAMKEGADALEAIIDHLAIHHTCTVSQADSEKENEEENAAGENIEKVDWKTHRKTRDGMSLGWLVPIATGFQGVSELGEAKNQRDPDTPHRFAESVVTLGEFKMPHRLNRVEELLWRYHQEGDLYLCHQSSHEHLSSSLNEDQEYSEFE
>NC_015276.1|WP_041647967.1|3649779_3651060_-|type-I-F-CRISPR-associated-protein-Csy1
MMDKNIQAFFEERKAAWLKKNLKASMSEVEVRQTEQECDEVFALKNWLPNAAKRAGQMSISTHPCTFSHPSARKNKNGYASAIIARSNRGEDGFLRTGNIDVEADALGNAAALDVYKFLTLKLADGQSLIQHIEQDSEQSKSLLELSNIAEGETYEQLKQGFLAMTSVDDNVITSSKIKQVYFPVSSDSTNQAYHQLSILTPSGIVFEMRKRLDAMRFGDEIKAAREKRKNNEQHENYREIYDLTTIGYGGTKPQNISVLNNQNGGKAHLLMSLPPQIEKRDIHFPNTDFFAQSINYFKCRDTFLRLHKLYQSDENNMHVRADRDDMYQNIVDYIIETMWQVRSVASEQYLETMSQLNQTQIIWLCAHTAEIRDTTDDWLDAILSSITQFVFHGYEKVLGKKAVKLGDAEKKHMAKIVEQNKEMLR
>NC_015276.1|WP_013662444.1|3651049_3651217_-|hypothetical-protein
MSKRLVKKETVTITRTEEISVLEEEGKVADWKRGMVALIVQLLKRFSIWKGNDDG
>NC_015276.1|WP_013662445.1|3651445_3654820_-|type-I-F-CRISPR-associated-helicase-Cas3
MMVTLVSQCEKNALKKTRRVLDAFANRIGDNTWQTLITEDGLLTVKKMLRKTASKNTAVSCHWIRSRSRSQLLWVVGNRKKFNDEGVVPVNTTRRNLLKSEIENDWHYLPLIKSLTAVAALLHDWGKASALFQEKLTPNSKNTFKGDPIRHEWISVLLLHALVKSSDGTDEGWLTQLSNGSLNENEPKQPLVNITSPLGSLPPLAQLVAWLVVSHHRLPLPPNQNDFKAEKAESIEQMLNRIQQTWGYENRYDEAEYAQRVKKCFQFPKGRLGQSSKWLSKLKRWSKQLLEHQMQAQTCIENGSFRLVLTHARLCLMLGDHYYSSQDAAKNWQDKTGLFANTDRKTKTLKQKLDEHLVGVAHHATQTAHLLPAFEKEPPVAEAVQSLRKPSPAGFKWQDKAVQKIQSWSAEKQRDKKHCGFFAINMASTGCGKTFANAKVMRALSKDQKSLRFILALGLRSLTLQTGHEYRERVGLDESELAVQIGSRAVIELDQRNAQKDKLDENAYEISGSESQETLLSGHIDYDCAIPEEGLATVLTQTRDKAFLYSPVLACTIDHIMGATETKRGGRYILPTLRLMSSDLVIDEIDDFTSDDLIAIGRLIQLAGMLGRKVMISSATIPPYMAEGYFNAYREGWNLYCQTRDAEHTIGCAWIDEFTTKVSNIASHELKAAIPEYRQQHADFIAKRVEQLNKQLARRKATLVECHEIIEKHQTQRQQDATVIESKQDAYFKAVFEQAWQLHKNHYLKDEQTNLKVSFGVVRVANISPCVALTRYLLEQDYPESIQVRVMAYHSQQVMLLRSEQEKHLDDVLKRKEKSGDAPKAFSNDIIRAHLKSIRSSHPEAKNALFILVATPVEEVGRDHDFDWAVVEPSSYRSIIQLAGRVKRHREGEVGQPNIGLMQYNLKGLRHSSDADQVVFHRPGFESGKVLLNNKRLDQLLDVEKVQQRLDAVPRIQQPQHIQAKTINKAKTASSLSDLEHIMNWHWLANYKDNGAGKLGGWLTQHWFLTALPQALTPFRGDDSTLKIYLVFDDRHQHLTFCEKDDEGHPVNRESVLNIQHVSLSDVARARLWLTRDFKESCEQLAQEKDTTPYIASLRYGEVRFNFDEKKHYLYSDQLGLVKK
>NC_015276.1|WP_013662446.1|3654816_3655794_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MEQFSPSDMKTILHSKRANMYYLEYCRVMQKDGRVLYLTEAKKENQYYNIPIANTTVLLLGTGTSITQAAMRMLSQAGVLVGFCGGGGTPLHMASEIEWLTPQSEYRPTEYLHGWLQFWFDDDKRLAAAKCFQNARIDFLDKIWNKDKDLKSEGFTTQDSMLLKAFETFHQRTEDAKKQSDLLLTEAQLTKVLYKFAANTMKIEDFTRQHQSTDIANDFLNHGNYLAYGLAASCLWVLGIPHGFAVMHGKTRRGALVFDLADLIKDAIVLPWAFVCAAENATEQEFRQQILQKFTDHKAMDFMFDTVKTIALQDYSSAQIEEQNL
>NC_015276.1|WP_013662447.1|3655922_3656786_-|WYL-domain-containing-protein
MEDKAAGHLKQREGHQHHWLIELIVFWEGQINATRLIETFGITRQTASQWLKQYQDDTNNTLKYSATAKAQVITQDFTPRYINQTIDEYLNWLELGSFPSESLTGSERSHIYKIRPPNRFVSPLVIRPLIKAIRNKTAVDCEYLSVKSADPIGRLIYPHSFVKAANRWHIRAYCEYRKNYLDFVISRFQSVEYDGKPAQNSHHDDTHWNAEIELILAPDSRLNDKQKRVIEQDYGMENGQLIIKTRAALVKYTLDDLQIKTKMLEADPQAQQLICVNYPDIKQWLYD
>NC_015276.1|WP_041648875.1|3657011_3658193_-|methyltransferase
MQNLSLTDKFKALDQWLTATQPLWQVATFAQTHWPWQHDYPKLVAYLKQHDDLPLEDVLSDIEKVLIEHVDGFQPAPFISLNELEASQKRELPSYFKSGIKGRKWAQIESFSKLVPIADSTLEWCAGKGHLGKAIAYRTPTRVVSLEWQQALCDAGEQDAQKLALNQTFVCADVLKGEANDALQQVKSAVALHACGDLHRILIEQSLANQLDAVTLSPCCYHLTQEDTYTPLSKTAQQSTLKLSKHDLRLAVKEIATAGKREQKQRDRELTYRLGFDAWQRQHRQIDEYLPVSKAPDAIMKQGFDAYCQWAATQKQLTLHSLESFSEYEQIGDIRKRRVLKVEAITQYFRRPLELWLVLDRALRLEESGYRVEIGEFCDKSITPRNLLIRATK
>NC_015276.1|WP_013662449.1|3658384_3659581_+|aspartate/tyrosine/aromatic-aminotransferase
MFKHLKAVPGDPLLALIVAHQQDTNPKKIDLGVGVYKNDSGQTPILESVKKAEAFMVENEITKSYLGVYGAPEFSPIIQDLLLGKDSNVIKQGRIQSTQTPGGTGALKVAADFISANLDGARLWVSDPTWGNHQSIFNSAGVEVITYPYYDAVTNGVRFEEMMATLEAETTEGDVLLLHACCHNPTGVDLNLEHWEALTELVNKRNLLPLIDAAYQGFGDGLEEDMAGLRYMAERVPSLLVANSFSKNFGIYRDRCGGLSVIAETAEEAKNAFSIIGQAIRANYSMPPAHGATLVHTIMTDPDLKALWETEVTQMRDRINDLRSKLVQKLAASGASKDFSFIEQQRGMFSYSGLSLEQVRQLRSEYSIYIADSGRMSIAGISDQNIDYLSESIAKVVG

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Crispr_ID: NC_015276_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_7

3896421-3898668

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CRISPRCasFinder
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CRT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	PILER-CR

37 spacers

The CRISPR arrays of NC_015276_7

>merge|NC_015276|7|3896421-3898668|CRISPRCasFinder,CRT,PILER-CR
ATACTAAGCTGCGTGTGCGGCAGCGGACGTTATCAAAACGGGTAACGGAAAGCTCTATATTTTCTAAGCTGCGTGTGCGGCAGCGAACGGCTTTCGATTGTCGCAATGGCGCGAATAATGTTTCTAAGCTGCGTGTGCGGCAGCGAACTTGGGACGAGATAAGCACGACGAGATGTGTATTTTCTAAGCTGCGTGTGCGGCAGCGAACGTTCCGATTCTCAAAATCTCGGAGGCATAGAGTTTCTAAGCTGCGTGTGCGGCAGCGAACAGTTTTGATGATTACTATGACTTCATATTCAATTTCTAAGCTGCGTGTGCGGCAGCGAACAGACGTGTTACGGAGGATGGGACACTGGGGGATTTCTAAGCTGCGTGTGCGGCAGCGAACTATGAAGTTTTTTAAAGGTAAAGCGGTCAAGTTTTCTAAGCTGCGTGTGCGGCAGCGAACGCAGAATACGACCTTCTCAGCGCTCGTAGAAATTTCTAAGCTGCGTGTGCGGCAGCGAACCCGATTTAACAACTAAAACCGTGTACACAATCTTTCTAAGCTGCGTGTGCGGCAGCGAACCTGGTCAGTATGTCGAATTAACAAAATACATATTTCTAAGCTGCGTGTGCGGCAGCGAACCCAAAGAATGTTTAAGAGAGTTCATGGTGAATTTTCTAAGCTGCGTGTGCGGCAGCGAACCCTGTTCGTGATTTGTATATGTGTTTTGAACATTTCTAAGCTGCGTGTGCGGCAGCGAACATGATACAAATTCGGAACTTCTAGACATGACATTTCTAAGCTGCGTGTGCGGCAGCGAACCCAGGTGAATGTGTTTAACACGGTGACCGAGATTTCTAAGCTGCGTGTGCGGCAGCGAACATCCGCGCTATCGCGCGGAAATCAAAGGGAAATTTCTAAGCTGCGTGTGCGGCAGCGAACGTAAAAGACGATGACTTAAACGACGATAAAGATTTCTAAGCTGCGTGTGCGGCAGCGAACTTGCACCCGGTACAGCGCGTGTTGTATTACAATTTCTAAGCTGCGTGTGCGGCAGCGAACACGGGGTGTTGTATCAATCACACGCTTAGCAATTTCTAAGCTGCGTGTGCGGCAGCGAACGCGATTAATGGTGCCCACGGAACGATAATAGATTTCTAAGCTGCGTGTGCGGCAGCGAACTTCAAGGTCTTTGCGCTCTCCAGAGGCTATAATTTCTAAGCTGCGTGTGCGGCAGCGAACCTAACGCCTTTTGACTTGGAGTAGTTACCAAATTTCTAAGCTGCGTGTGCGGCAGCGAACAAAAGCCGCGAACGACTTATTTCTAACGAGGTTTTCTAAGCTGCGTGTGCGGCAGCGAACTTTACGTGATGATGCTCGCTCCGGTGTGAAATTTTCTAAGCTGCGTGTGCGGCAGCGAACGATGCCCAGTGCCGTCATGTAGTCTGGGTCGATTTCTAAGCTGCGTGTGCGGCAGCGAACAGACGCTAATTACGTGCTGAGCGAGCTAATGCTTTCTAAGCTGCGTGTGCGGCAGCGAACATTACGTGCAAAGCTCGCTAATGCGTCGATTATTTCTAAGCTGCGTGTGCGGCAGCGAACAAGGGGAAGTCGGTTGCGGATTCGGTAAGTCATTTCTAAGCTGCGTGTGCGGCAGCGAACGAGAATATTCGTCTCGGCGCGATGCTCGGCAATTTCTAAGCTGCGTGTGCGGCAGCGAACGAAAAGACCTGTAATGTTATTTTTTGATAAACTTTCTAAGCTGCGTGTGCGGCAGCGAACCCTCCAATGTACAGTCTAGTTAACAGATTAAATTTCTAAGCTGCGTGTGCGGCAGCGAACAGCATTTCGCTTTTCAATTAGAGTTATATACTTTTCTAAGCTGCGTGTGCGGCAGCGAACTAAACCGAGACGATATCCGAGACGAATTGTTCTTTCTAAGCTGCGTGTGCGGCAGCGAACACGAGTTTTCATGTCCTCGGTGACGTGTTTTATTTCTAAGCTGCGTGTGCGGCAGCGAACTTGTTTTTAAGGCCATTCATTTGCCGCTTGAATTTCTAAGCTGCGTGTGCGGCAGCGAACCATTTTATGTGGCTGTTGGCGGGGCGGTTCTATTTCTAAGCTGCGTGTGCGGCAGCGAACTGCGTCGGGCATGTTTTTTATCAATTCGTAAATTTCTAAGCTGCGTGTGCGGCAGCGAACGATCCCGCAATGGTGGGGTGATTTCCAAGTCTTTTCTAAGCTGCGTGTGCGGCAGCGAAC

>NC_015276|7|6|3896421-3898668|CRISPRCasFinder
ATACTAAGCTGCGTGTGCGGCAGCGGAC	GTTATCAAAACGGGTAACGGAAAGCTCTATAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GGCTTTCGATTGTCGCAATGGCGCGAATAATG
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGGGACGAGATAAGCACGACGAGATGTGTAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GTTCCGATTCTCAAAATCTCGGAGGCATAGAG
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGTTTTGATGATTACTATGACTTCATATTCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGACGTGTTACGGAGGATGGGACACTGGGGGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TATGAAGTTTTTTAAAGGTAAAGCGGTCAAGT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCAGAATACGACCTTCTCAGCGCTCGTAGAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCGATTTAACAACTAAAACCGTGTACACAATC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CTGGTCAGTATGTCGAATTAACAAAATACATA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCAAAGAATGTTTAAGAGAGTTCATGGTGAAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCTGTTCGTGATTTGTATATGTGTTTTGAACA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATGATACAAATTCGGAACTTCTAGACATGACA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCAGGTGAATGTGTTTAACACGGTGACCGAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATCCGCGCTATCGCGCGGAAATCAAAGGGAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GTAAAAGACGATGACTTAAACGACGATAAAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGCACCCGGTACAGCGCGTGTTGTATTACAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ACGGGGTGTTGTATCAATCACACGCTTAGCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCGATTAATGGTGCCCACGGAACGATAATAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTCAAGGTCTTTGCGCTCTCCAGAGGCTATAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CTAACGCCTTTTGACTTGGAGTAGTTACCAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AAAAGCCGCGAACGACTTATTTCTAACGAGGT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTTACGTGATGATGCTCGCTCCGGTGTGAAAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GATGCCCAGTGCCGTCATGTAGTCTGGGTCGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGACGCTAATTACGTGCTGAGCGAGCTAATGC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATTACGTGCAAAGCTCGCTAATGCGTCGATTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AAGGGGAAGTCGGTTGCGGATTCGGTAAGTCA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GAGAATATTCGTCTCGGCGCGATGCTCGGCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GAAAAGACCTGTAATGTTATTTTTTGATAAAC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCTCCAATGTACAGTCTAGTTAACAGATTAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGCATTTCGCTTTTCAATTAGAGTTATATACT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TAAACCGAGACGATATCCGAGACGAATTGTTC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ACGAGTTTTCATGTCCTCGGTGACGTGTTTTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGTTTTTAAGGCCATTCATTTGCCGCTTGAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CATTTTATGTGGCTGTTGGCGGGGCGGTTCTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TGCGTCGGGCATGTTTTTTATCAATTCGTAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GATCCCGCAATGGTGGGGTGATTTCCAAGTCT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC

>NC_015276|7|4|3896421-3898668|CRT
ATACTAAGCTGCGTGTGCGGCAGCGGAC	GTTATCAAAACGGGTAACGGAAAGCTCTATAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GGCTTTCGATTGTCGCAATGGCGCGAATAATG
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGGGACGAGATAAGCACGACGAGATGTGTAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GTTCCGATTCTCAAAATCTCGGAGGCATAGAG
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGTTTTGATGATTACTATGACTTCATATTCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGACGTGTTACGGAGGATGGGACACTGGGGGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TATGAAGTTTTTTAAAGGTAAAGCGGTCAAGT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCAGAATACGACCTTCTCAGCGCTCGTAGAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCGATTTAACAACTAAAACCGTGTACACAATC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CTGGTCAGTATGTCGAATTAACAAAATACATA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCAAAGAATGTTTAAGAGAGTTCATGGTGAAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCTGTTCGTGATTTGTATATGTGTTTTGAACA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATGATACAAATTCGGAACTTCTAGACATGACA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCAGGTGAATGTGTTTAACACGGTGACCGAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATCCGCGCTATCGCGCGGAAATCAAAGGGAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GTAAAAGACGATGACTTAAACGACGATAAAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGCACCCGGTACAGCGCGTGTTGTATTACAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ACGGGGTGTTGTATCAATCACACGCTTAGCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCGATTAATGGTGCCCACGGAACGATAATAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTCAAGGTCTTTGCGCTCTCCAGAGGCTATAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CTAACGCCTTTTGACTTGGAGTAGTTACCAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AAAAGCCGCGAACGACTTATTTCTAACGAGGT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTTACGTGATGATGCTCGCTCCGGTGTGAAAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GATGCCCAGTGCCGTCATGTAGTCTGGGTCGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGACGCTAATTACGTGCTGAGCGAGCTAATGC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATTACGTGCAAAGCTCGCTAATGCGTCGATTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AAGGGGAAGTCGGTTGCGGATTCGGTAAGTCA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GAGAATATTCGTCTCGGCGCGATGCTCGGCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GAAAAGACCTGTAATGTTATTTTTTGATAAAC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCTCCAATGTACAGTCTAGTTAACAGATTAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGCATTTCGCTTTTCAATTAGAGTTATATACT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TAAACCGAGACGATATCCGAGACGAATTGTTC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ACGAGTTTTCATGTCCTCGGTGACGTGTTTTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGTTTTTAAGGCCATTCATTTGCCGCTTGAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CATTTTATGTGGCTGTTGGCGGGGCGGTTCTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TGCGTCGGGCATGTTTTTTATCAATTCGTAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GATCCCGCAATGGTGGGGTGATTTCCAAGTCT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC

>NC_015276|7|8|3896481-3898668|PILER-CR
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GGCTTTCGATTGTCGCAATGGCGCGAATAATG
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGGGACGAGATAAGCACGACGAGATGTGTAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GTTCCGATTCTCAAAATCTCGGAGGCATAGAG
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGTTTTGATGATTACTATGACTTCATATTCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGACGTGTTACGGAGGATGGGACACTGGGGGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TATGAAGTTTTTTAAAGGTAAAGCGGTCAAGT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCAGAATACGACCTTCTCAGCGCTCGTAGAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCGATTTAACAACTAAAACCGTGTACACAATC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CTGGTCAGTATGTCGAATTAACAAAATACATA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCAAAGAATGTTTAAGAGAGTTCATGGTGAAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCTGTTCGTGATTTGTATATGTGTTTTGAACA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATGATACAAATTCGGAACTTCTAGACATGACA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCAGGTGAATGTGTTTAACACGGTGACCGAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATCCGCGCTATCGCGCGGAAATCAAAGGGAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GTAAAAGACGATGACTTAAACGACGATAAAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGCACCCGGTACAGCGCGTGTTGTATTACAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ACGGGGTGTTGTATCAATCACACGCTTAGCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GCGATTAATGGTGCCCACGGAACGATAATAGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTCAAGGTCTTTGCGCTCTCCAGAGGCTATAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CTAACGCCTTTTGACTTGGAGTAGTTACCAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AAAAGCCGCGAACGACTTATTTCTAACGAGGT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTTACGTGATGATGCTCGCTCCGGTGTGAAAT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GATGCCCAGTGCCGTCATGTAGTCTGGGTCGA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGACGCTAATTACGTGCTGAGCGAGCTAATGC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ATTACGTGCAAAGCTCGCTAATGCGTCGATTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AAGGGGAAGTCGGTTGCGGATTCGGTAAGTCA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GAGAATATTCGTCTCGGCGCGATGCTCGGCAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GAAAAGACCTGTAATGTTATTTTTTGATAAAC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CCTCCAATGTACAGTCTAGTTAACAGATTAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	AGCATTTCGCTTTTCAATTAGAGTTATATACT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TAAACCGAGACGATATCCGAGACGAATTGTTC
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	ACGAGTTTTCATGTCCTCGGTGACGTGTTTTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TTGTTTTTAAGGCCATTCATTTGCCGCTTGAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	CATTTTATGTGGCTGTTGGCGGGGCGGTTCTA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	TGCGTCGGGCATGTTTTTTATCAATTCGTAAA
TTTCTAAGCTGCGTGTGCGGCAGCGAAC	GATCCCGCAATGGTGGGGTGATTTCCAAGTCT
TTTCTAAGCTGCGTGTGCGGCAGCGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013662662.1\|3905031_3905448_+\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NC_015276.1\|WP_013662652.1\|3889817_3890852_-\|divergent-polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|377404
NC_015276.1\|WP_013662658.1\|3900382_3901927_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448
NC_015276.1\|WP_013662653.1\|3890852_3892124_-\|S41-family-peptidase	unknown	unknown	gnl\|CDD\|223864
NC_015276.1\|WP_013662650.1\|3886997_3887909_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182689
NC_015276.1\|WP_013662659.1\|3902091_3902934_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_015276.1\|WP_013662661.1\|3903905_3904574_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662663.1\|3905463_3905718_+\|glutaredoxin-3	unknown	unknown	gnl\|CDD\|274017
NC_015276.1\|WP_013662664.1\|3905766_3906243_+\|protein-export-chaperone-SecB	unknown	unknown	gnl\|CDD\|180234
NC_015276.1\|WP_013662655.1\|3893374_3894910_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463
NC_015276.1\|WP_013662648.1\|3884839_3885721_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|183080
NC_015276.1\|WP_013662651.1\|3887995_3889111_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380565
NC_015276.1\|WP_085987022.1\|3884129_3884846_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223487
NC_015276.1\|WP_013662665.1\|3906548_3908207_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225559
NC_015276.1\|WP_013662666.1\|3908279_3908879_+\|penicillin-binding-protein-activator-LpoB	unknown	unknown	gnl\|CDD\|372439
NC_015276.1\|WP_013662657.1\|3898995_3900267_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223737
NC_015276.1\|WP_013662649.1\|3885717_3886998_-\|high-affinity-branched-chain-amino-acid-ABC-transporter-permease-LivM	unknown	unknown	gnl\|CDD\|236896
NC_015276.1\|WP_013662654.1\|3892166_3893303_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|227278
NC_015276.1\|WP_013662660.1\|3903054_3903858_+\|DUF1338-domain-containing-protein	unknown	unknown	gnl\|CDD\|319960
NC_015276.1\|WP_013662656.1\|3895168_3896095_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013662662.1\|3905031_3905448_+\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.17316e-28
NC_015276.1\|WP_013662652.1\|3889817_3890852_-\|divergent-polysaccharide-deacetylase-family-protein	gnl\|CDD\|377404	pfam04748, Polysacc_deac_2, Divergent polysaccharide deacetylase. This family is divergently related to pfam01522 (personal obs:Yeats C).	6.92259e-91
NC_015276.1\|WP_013662658.1\|3900382_3901927_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0
NC_015276.1\|WP_013662653.1\|3890852_3892124_-\|S41-family-peptidase	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	2.56327e-115
NC_015276.1\|WP_013662650.1\|3886997_3887909_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|182689	PRK10740, PRK10740, high-affinity branched-chain amino acid ABC transporter permease LivH.	4.36747e-102
NC_015276.1\|WP_013662659.1\|3902091_3902934_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.52249e-36
NC_015276.1\|WP_013662666.1\|3908279_3908879_+\|penicillin-binding-protein-activator-LpoB	gnl\|CDD\|372439	pfam13036, LpoB, Peptidoglycan-synthase activator LpoB. This is a family of Gram-negative bacterial outer membrane lipoproteins. LpoB is required for the function of the major peptidoglycan synthase enzyme PBP1B. It interacts with PBP1B protein via the UvrB-like non-catalytic domain on that protein. LpoB has a 54-aa-long flexible N-terminal stretch followed by a globular domain with similarity to the N-terminal domain of the prevalent periplasmic protein TolB. The long, flexible N-terminal region of LpoB enables it to span the periplasm and reach its docking site in PBP1B. Peptidoglycan is the essential polymer within the sacculus that surrounds the cytoplasmic membrane of bacteria.	2.50919e-51
NC_015276.1\|WP_013662663.1\|3905463_3905718_+\|glutaredoxin-3	gnl\|CDD\|274017	TIGR02181, GRX_bact, Glutaredoxin, GrxC family. Glutaredoxins are thioltransferases (disulfide reductases) which utilize glutathione and NADPH as cofactors. Oxidized glutathione is regenerated by glutathione reductase. Together these components compose the glutathione system. Glutaredoxins utilize the CXXC motif common to thioredoxins and are involved in multiple cellular processes including protection from redox stress, reduction of critical enzymes such as ribonucleotide reductase and the generation of reduced sulfur for iron sulfur cluster formation. Glutaredoxins are capable of reduction of mixed disulfides of glutathione as well as the formation of glutathione mixed disulfides. This family of glutaredoxins includes the E. coli protein GrxC (Grx3) which appears to have a secondary role in reducing ribonucleotide reductase (in the absence of GrxA) possibly indicating a role in the reduction of other protein disulfides. [Energy metabolism, Electron transport].	1.00539e-46
NC_015276.1\|WP_013662664.1\|3905766_3906243_+\|protein-export-chaperone-SecB	gnl\|CDD\|180234	PRK05751, PRK05751, preprotein translocase subunit SecB; Validated.	1.7859e-70
NC_015276.1\|WP_013662655.1\|3893374_3894910_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NC_015276.1\|WP_013662648.1\|3884839_3885721_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|183080	PRK11300, livG, leucine/isoleucine/valine transporter ATP-binding subunit; Provisional.	6.98604e-132
NC_015276.1\|WP_013662651.1\|3887995_3889111_-\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380565	cd06342, PBP1_ABC_LIVBP-like, type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.	1.08244e-138
NC_015276.1\|WP_085987022.1\|3884129_3884846_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223487	COG0410, LivF, ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism].	2.39773e-131
NC_015276.1\|WP_013662665.1\|3906548_3908207_+\|hypothetical-protein	gnl\|CDD\|225559	COG3014, COG3014, Uncharacterized protein conserved in bacteria [Function unknown].	1.77209e-08
NC_015276.1\|WP_013662657.1\|3898995_3900267_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	8.90602e-69
NC_015276.1\|WP_013662649.1\|3885717_3886998_-\|high-affinity-branched-chain-amino-acid-ABC-transporter-permease-LivM	gnl\|CDD\|236896	PRK11301, livM, leucine/isoleucine/valine transporter permease subunit; Provisional.	7.08732e-164
NC_015276.1\|WP_013662654.1\|3892166_3893303_-\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	1.75246e-65
NC_015276.1\|WP_013662660.1\|3903054_3903858_+\|DUF1338-domain-containing-protein	gnl\|CDD\|319960	cd16350, VOC_like, uncharacterized subfamily of the vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.52829e-133
NC_015276.1\|WP_013662656.1\|3895168_3896095_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	3.56159e-81

>NC_015276.1|WP_013662656.1|3895168_3896095_-|LysR-family-transcriptional-regulator
MRHYIPSSTALKCFEASVRHLSFTRAAEELHLTQSAVSRQIRNLEEFLSRELFIRLNKRLVLTGTGDAYYKEILPLLDAMEGASLRMLRREDEKTTLRIASLPTLASYWLIPKLNEFQELHPEFQIKVSALESGAQIESDNTDIILHYGGDHWPKAISHHLMGEQVIAVCSPELIGLSSPRRSLPSSVDLKNKTVSANVLNYELIHLSARVNAWPDWFAANKLEQSALSGATFEHFHMLLEAAKQSMGAAILPTFIAEQSLARGELIAPFGDAIDTPHEYFLSYPADRADLEQVVMFRDWLIEKMRSS
>NC_015276.1|WP_013662655.1|3893374_3894910_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSKKTTALFILDGWGYSETSKSNAIAAATTPNWDALWASKPHTLIKTSGMAVGLPDGQMGNSEVGHMNLGAGRVVYQNFTRISKAIDDGSFFENTELVNTVDKAVAAGKAVHILGLLSAGGVHSHHEHIMAMAELAVKRGAKAIYVHGFTDGRDTPPRSAQGPVSELDAKLKALGVGKIATLTGRYFAMDRDNRWERVQQAYDAIVSGNGLYEAESAEQAIAAAYERDENDEFVKATVIGDAVKVDDGDAIVFANFRPDRARQLTRAFTDASFSGFERNETPSLSGFVTFTEYASDISASVAFPPVALSNTLGEILSKENKTQLRIAETEKYAHVTFFFNGGEEAVFAGEERELIPSPDVATYDLKPEMSAPEVTDKLVEVIEAGKYDTIICNFANGDMVGHSGIFDAAVQAVEAVDACIGRVIEALEKNGGQCLITADHGNVEQMLSDDGSQPLTSHTLEPVPLVLYTPEENVSIKEGALCDIAPTLLDMMGMVKPDEMTGESLLVRNKA
>NC_015276.1|WP_013662654.1|3892166_3893303_-|peptidoglycan-DD-metalloendopeptidase-family-protein
MLFRVFFGLCLLCLSSLGVAAAQPQTPEEARQQIETLQKDLKKLNGWLKEIKSERSDVEKQLESKEQSIQLLHKKIQELQLSLKKGEQQLSELSKQQRNLQLSIQQQNDQIAAQLRAVYRSGEQDGLKLLLSDNQSADAMRLVHYNRYFSQARQSVINGYVNEVRELSLVEKSIRSHRAQQIQEQTNLQKQRTALKAERLQRKTLLAKLNQDLKTGNQKQAQLSKNQKQLSALLERLEEALVDIQIPDQDVSFASQKGKLVKPIARLTKVPDNGQINLGGITLKAKEGDNVRAIFHGRVVFADWMRGFGFLIILDHGDGYMSLYGYNQSILKDVGEWVAANEVIATVGSSGGRLDPGLFFAIRHNSVPLSPLKWVGRG
>NC_015276.1|WP_013662653.1|3890852_3892124_-|S41-family-peptidase
MRIINNILCGVALVLTVTPSMAEEKSSIPLEEIQSFVETFETIREGYVEDLDDRAILDKALKGMVAALDPHSNYLTSEEMKEFEKVTSGNYAGIGVEVEMADNVLTIVTPIDGSPAKEAGLEPGDVVVRIDSQLVSGMSLQDVTILMRGEVGTSVRLDVERDGQIKEYEIERRLIDESSITSKWLDKDDGIAYIRLSQFQGDSGEEFASAIKQLKQDQPIEGVILDLRNNPGGVLQSAVSIVDSLVDNGMIVYTDGRHQLSKTEFKASKRATVLPDAPVVVMINEGSASASEVVAGALQDHKRAVILGTESFGKGTVQTVVPLTNGAAVKLTTALYFTPKGRSIQAQGIRPDIIIPQADITVPDDAFFIKEAELKGHISNGTGGEERTSSDVQSGLSQLAASDFQLFQALTILQSVPKLTKKL
>NC_015276.1|WP_013662652.1|3889817_3890852_-|divergent-polysaccharide-deacetylase-family-protein
MNRTESLKSCYRYKVVALFLSVVASVYSVFVNAHDDASSLGPIVTAPKATTSISSPAEIDWLPNDLYVSNVDGLFDEEAPADASSPVGSGSLEPFIVPFSPFYQRVRLTPPSEVIRKDKVKSREQLPRISIIIDDLGYNRRGMESSLNLPVEVALAILPHTPFGKKTALKSIEQNRVTLLHAPMENQRELKLGPGGLYASMGEEEFKSVLRDDLASLPGIKGVNNHMGSLLTTDSQAMNWVMQVIGDRSLFFVDSVTSADSVAYTMALRHSINTTKRDVFLDNIRSEKKIEQQFLKLIQLAHQNGHAIAIGHPYPETMAYLSKRLADLSKLSVRLVPIDELMGQ
>NC_015276.1|WP_013662651.1|3887995_3889111_-|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MSNAVVKKTLVSLAIAGAMTAAQADVVIGVAGPHTGAYAAFGAQLWNGASAAAKAINDAGGIDGEMIKLVKADDACEPKQAVSVANRLVDSDEAVAVVGHFCSSSSIPASNIYEEAGVLQVTPASTNPGYTDRGLPNVFRVCGRDDQQGDVAASYIVDELGATRVAVIHDKDTYGKGLADAMKSTLNAYGVKEVLYEGLTRGEKDFNALVTKIRSVDADVVYFGGLHSEAGPLVRQMREQGLTAKFISGDGIVSDEFVSVAGSADYVDGVLMTFGADPTSYAAGKAVVKKFRDSGVEPEGYVMYSYAAMQVVAEALKNADLDPVKASDWLHANKVETVMGTKAFDEKGDLLVSDYVMYEWDKQGKYSMLGM
>NC_015276.1|WP_013662650.1|3886997_3887909_-|branched-chain-amino-acid-ABC-transporter-permease
MDIILQQLVNGLSLGSVYGLIAIGYTMVYGIIGMINFAHGDVYMVSAYITAVAIALLSFFGIESFPVIIFGTLIFTIFVTGVYGWVIERVAYRPLRGSSRLSILISAIGMSLILQNYVQLSQGAKQQGVPTLLSGAIRFDIGDGFVQITYMKLFILVASFVGMAVLTYIIQKTKLGRMCRATQQDPKMASILGIDTDKIISTVFVIGATMAALAGVLVTLDYGGFDFYVGFIIGIKAFTAAVLGGIGSLPGAMLGGIILGLSEALFAGLISSDYKDVFSFSLLVVILIFRPSGLLGKPEVEKV
>NC_015276.1|WP_013662649.1|3885717_3886998_-|high-affinity-branched-chain-amino-acid-ABC-transporter-permease-LivM
MSQAATGIELKKTVIDSVLAGLLALIVFGPIVGLVLDGFDFNAEPKRLFMIVAVVMAGRFAASCFFQSTKGKDFLYKHSSKDEGVHVLSPDHKSKLKWIIPLTIVIAFLVPFIASKYILTVVILGLIYVLLGLGLNIVVGLAGLLDLGFVGFYAIGAYGLALGYEHLGLGFWSMLPIAAIVAAIFGAILGFPVLRMHGDYLAIVTLGFGEIIRLVLTNWTELTHGPNGMNAPLPTFFGMEFKRRASEGHVPFHEFFGLSYSSAYKYIFIYLILLLVVLGVLYVKKRLTQMPIGRAWEALREDEIACRSLGLNHVLVKLSAFMIGASTGGLAGVFFATYQGFVNPSSFTFFESALILAIVVLGGMGSTLGVVIAAFVLTVAPEMLREFADYRVLAFGILMVLMMIWKPRGLVRMTRIGVASREGNVK
>NC_015276.1|WP_013662648.1|3884839_3885721_-|ATP-binding-cassette-domain-containing-protein
MSQDSILKVENLVMHFGGIKALNDVNFEIKRGSVSALIGPNGAGKTTVFNCLTGFYKATGGSIMLHASGKSTSVIEVLGEPFQVSDYLNPVAFIKRLKYKMFGGSHLVNRAGLARTFQNIRLFKEMSVVENLLVAQHMRVNRGMFAGILKTKAFKESEEEALERAFYWLGVVDLKEFANRLAGELSYGQQRRLEIARAMCTNPEIVCLDEPAAGLNPSETEALTKMIRVLRDEHNTTVLLIEHDMGMVMNISDYIVVLDHGEVIARGGPDDIKSNPKVIAAYLGAEEGEEVTL
>NC_015276.1|WP_085987022.1|3884129_3884846_-|ABC-transporter-ATP-binding-protein
MMTSLMEFKEVDVHYGPIQALKKVSLEVNEGEIVTMIGANGAGKSTLLMSIFGQPRVSAGQIIYRGEDISKKSAHYVASNGLAQSPEGRRIFPGMTVEENLLMGTIPIGMDHADEDMRKMFDLFPRLEERRNQRASTMSGGEQQMLAIARALMSRPKLLLLDEPSLGLAPIIVKQIFEILKDVASTGMTIFLVEQNANHALKLADRGYVMVNGEIRMTGTGDELLVNPEVREAYLGGH
>NC_015276.1|WP_013662657.1|3898995_3900267_-|FAD-binding-oxidoreductase
MIDSDCNSLWRASSPAAPELTSLSSDMVVDVAIVGAGFTGLSAALHLAKKGFSVVVLEAQEVGFGGSGRNVGLANAGLWLEPDELDKQLGLEDGKRLYDALSVAPDTVFSLIDEYQIECEATRHGTLHAGVGKAGLAQLQRRCDQLQQRGAPVQLLGMSDAQTRIGSEKFCGALFDPRAGTIQPLAYARGLAHAALKEGATIFEYSPVTSIVPEQDSWKLDTEKGSVSAEKVVLATNAYCEFGVQEQARKFVPIFYSQLATKPLTEKELERVLPNKEGCWDTCTVMSSFRLDQQGRLIFGGMGGTGQRLTNWATQRVHELFPTLSNLEWDYCWTGKIAYSEDHLPHCQQLQRGLFSVAGYSGRGIGPGTVMGKELAHWFAGDIESLSAPTSVLRDTPLRELKRVFYEVGAKAYHLGQSKHLLT
>NC_015276.1|WP_013662658.1|3900382_3901927_-|aldehyde-dehydrogenase-family-protein
MTLTCLETLGINSLKQGDRYFSVLTGNVCEMGQGDAFSAHSPIDGAVLSQFNNAVPEQLSSVASELQDAFKALRVIPAPRRGELVRRIGEEARKYKEELAQVISLEAGKILPEALGEVQEWIDVCDFAVGQSRMLHGLSIVSERPGHRMMEQWQPLGPVAVITAFNFPMAVWAWNAMLGLVCGDPILLKPSEKAPLCALAMYQIAQNVIADMPDIPKASVSVMIGGRDLGEAIASNPVFPLVSATGSTAMGKAVAQTVAARLGRSLLELGGNNAMIVSPTADLDLALRAIVFSAAGTAGQRCTTLRRLITHESVVDGLVERLVKSYSSLSIGNPMEEGNLVGPLIDEGSFGRMQASLAAAKEQGGEVVYGGERVTEGVPASGFYVKPAIVRIAHDAPIVQEETFAPILYVLTYSEFEDAIEIQNNVPQGLSSAVFTESMREAELFMSPAGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWRNYMRRTTNTINYGGDLPLAQGIVFE
>NC_015276.1|WP_013662659.1|3902091_3902934_+|LysR-family-transcriptional-regulator
MDIRSLRYFIAVFEERSLSAAAKRCFVAQPSISATLAQLEEDLSTKLFVRHSKGVSPTDSGSQLYPHACRMVNDLNSLRGLFSENTTPLSLTISLTPFLSGAFISQVIKKMLDEISGLTLNLIDESESADLRFTCSRYTSEDDVFYPLWEDDYVIAMPEGHWLSEFPSLSIKQIDRQPFISRTPCDILESWNYLMQKQGLKTDIRAQVKTEEYALDLVAAGLGISLIPEHSSRGRSDICIRPINDVKLKRVVGLAHCKDRSFPAHLINTILSSKQQLLLT
>NC_015276.1|WP_013662660.1|3903054_3903858_+|DUF1338-domain-containing-protein
MNTNDFFDSLWSKYTQITPQAQRIQSLFQDQGETVLNDHVAFRTFNNSPIELEKLEPQLSALGYKAYGAFRFENKHLKARCYKHESDTLAPKIFLSELITEELPAVCQEIITKLTEQIALNAVQSPDIFWAGTLWDKISEEDYLTLAEHSEYAAWLSTMGLQANHFTVSINHLKKFPTIEEVNSLLQNEGYTLNSVGGIVKGSPQLYLEQSSTMADKVEVTFANDIKRTIPSCFYEFAKRHKQPDGVLFDSFIEGNADKIFDSTNAQ
>NC_015276.1|WP_013662661.1|3903905_3904574_-|hypothetical-protein
MFSFGRKANENAVTKGQWLKCISAFLAVLLLSACSSSAHKSNFEEKRKETQVALSEKLESLWERAHIIPDLQRGAPLVSHSERGQNAILQQNAANLQLADGLLASLNKRVLDRKSDGKKGDRIRLTLVLASDKNQMAFSADPIEVWRGDVSEWVLSSPAGERLSVRVVWNEQGPLYLEGQQTADVSLAMPSTPFITNLFYYGNAVTAQKALSLLLSVDVNIK
>NC_015276.1|WP_013662662.1|3905031_3905448_+|rhodanese-like-domain-containing-protein
MIDQILEFSTNHWEMVAVFFFVLAAVVFVEMRGNARGITTASLTDLVNNKNAAVIDIRPTKEFRAGHITGAINIPANKLKDKNAELEKHKSNPIILVCKTGMTAGSNAKELIKAGFEVYKLQGGIAEWENANLPLVKA
>NC_015276.1|WP_013662663.1|3905463_3905718_+|glutaredoxin-3
MADVTIYSSDYCPFCVRAKQLLDMKNVSFNEINVDGNRTLRQEMMEKSGRHTVPQIWIDNHHVGGCDELFALEREQKLDPMLSV
>NC_015276.1|WP_013662664.1|3905766_3906243_+|protein-export-chaperone-SecB
MADENNQEAQQAQGPVLQMQRVFLKDISFESPRSPMIFQEEWKPELGLELNTKSRQVGENVYEVVLEITVNVKNEGEPAYLVQVQQGGLFTISGLEEQQLHHALGAFCPGTLFPYARENIDAIVVKGSFSPVMLAPINFDALYLESLQKQQPEAETTQ
>NC_015276.1|WP_013662665.1|3906548_3908207_+|hypothetical-protein
MRFIVVCLVTLFINGCATYRNDIDEGLTLAHEGNWKAAEESMDKALDSSQDQLLFYLEKGALAQYQGDYQRSNELLEEAEKISDTFFSSTYSNRAWALLTNPRQSDYRGNGLERVYISYLKSLNYLALSGQATNTSKKQQLMDSALVEARRIDLKLNEIAAQSTSYSELNAKEDQAFYMKALEWLGNFYQGGRSSEQYEYREDAWARYLEGIQYEKSKEYDDARISYESAAQLYEAGYAKQYDLTPDAATRAWLDAIRMMDKGGWSNAEINEAIDVHLTPSYKTLLEEYNEHDAEIVVLEHQGFVPAKKEMSLLLLADPAAYSLVLEPLHGGGNTKENDAFRWFTMVYSDATPLSLIANYKAGGAWRAFDGLFNKRVILGRPVWSQLSATGLEGMLMNQPLRITVPFYPRFSLDQSKTDVTAGTFTDNLSLRMTSLADISLQNQLKTAQRDIYESLIRELIRGWLAYQVQSNIEDQGASMLIGLVSQVAVFASSASDTRNWLTLPAQVRLTRMPIESGSYTPSYSVGNKTFNMAETSIEKDGLVIWNIRNPN
>NC_015276.1|WP_013662666.1|3908279_3908879_+|penicillin-binding-protein-activator-LpoB
MFKSLSRSIFVLFTVLTITACSSGGVKRISTDEEVALSDRWNDTDSRLVAEAMMGEMLTFPWYRQYKVEHDGNPTVIIQSIRNKSHEHIPVDTFINDIKRSFLKEGKVDFVVSGEEREDIRTEREDQEMNAAEGTAAEFGQEQGAQFALSGTINSIVDSNGDQRVTFYQVDLKLINMTTNREVWNGQKKIKKLADKGFF

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Crispr_ID: NC_015276_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_8

3931695-3931826

Orphan

Consensus_repeat	Method
GATGTGCTTGTAATGTCGTTGAATGACCTCCTTTTAATCTCCCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015276_8

>merge|NC_015276|8|3931695-3931826|CRISPRCasFinder
GATGTGCTTGTAATGTCGTTGAATGACCTCCTTTTAATCTCCCCCTCTAATTTTCTTCTCGATAGCGGGGGAGAAACTGTCCGCAGCGATGTGCTTGTAATGTCGTTGAATAACCTCCTTTTAATCTCCCCC

>NC_015276|8|7|3931695-3931826|CRISPRCasFinder
GATGTGCTTGTAATGTCGTTGAATGACCTCCTTTTAATCTCCCCC	TCTAATTTTCTTCTCGATAGCGGGGGAGAAACTGTCCGCAGC
GATGTGCTTGTAATGTCGTTGAATAACCTCCTTTTAATCTCCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013662689.1\|3934493_3934805_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380355
NC_015276.1\|WP_049787792.1\|3928061_3928916_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|197666
NC_015276.1\|WP_013662685.1\|3928996_3929770_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662692.1\|3937886_3940325_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|131764
NC_015276.1\|WP_013662682.1\|3927131_3927428_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|367760
NC_015276.1\|WP_013662693.1\|3940330_3940636_-\|NIPSNAP-family-protein	unknown	unknown	gnl\|CDD\|311781
NC_015276.1\|WP_013662679.1\|3924626_3925289_-\|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl\|CDD\|235552
NC_015276.1\|WP_013662690.1\|3935162_3936791_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NC_015276.1\|WP_041648935.1\|3942515_3943259_+\|histidine-utilization-repressor	unknown	unknown	gnl\|CDD\|188194
NC_015276.1\|WP_013662683.1\|3927492_3927981_-\|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase	unknown	unknown	gnl\|CDD\|179953
NC_015276.1\|WP_013662694.1\|3940636_3940861_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_041648931.1\|3922862_3923504_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_015276.1\|WP_013662691.1\|3936782_3937709_-\|histone-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|212541
NC_015276.1\|WP_013662687.1\|3931906_3933673_-\|gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|223482
NC_015276.1\|WP_013662686.1\|3929874_3931158_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662695.1\|3940967_3942350_-\|formimidoylglutamate-deiminase	unknown	unknown	gnl\|CDD\|236420
NC_015276.1\|WP_013662678.1\|3923749_3924517_+\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|236702
NC_015276.1\|WP_013662681.1\|3926688_3926928_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|366598
NC_015276.1\|WP_013662688.1\|3933963_3934326_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662680.1\|3925301_3926702_-\|anthranilate-synthase-component-I	unknown	unknown	gnl\|CDD\|273819

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013662689.1\|3934493_3934805_+\|cupin-domain-containing-protein	gnl\|CDD\|380355	cd02226, cupin_YdbB-like, Bacillus subtilis YdbB and related proteins, cupin domain. This family includes bacterial proteins homologous to YdbB, a Bacillus subtilis protein of unknown function. It also includes protein Nmb1881 From Neisseria meningitidis, also of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.0543e-06
NC_015276.1\|WP_049787792.1\|3928061_3928916_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	4.04158e-10
NC_015276.1\|WP_013662692.1\|3937886_3940325_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|131764	TIGR02717, Uncharacterized_protein_MJ0590, acetyl coenzyme A synthetase (ADP forming), alpha domain. Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.	1.11837e-60
NC_015276.1\|WP_013662682.1\|3927131_3927428_+\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	3.00963e-06
NC_015276.1\|WP_013662693.1\|3940330_3940636_-\|NIPSNAP-family-protein	gnl\|CDD\|311781	pfam07978, NIPSNAP, NIPSNAP. Members of this family include many hypothetical proteins. It also includes members of the NIPSNAP family which have putative roles in vesicular transport. This domain is often found in duplicate.	1.83057e-24
NC_015276.1\|WP_013662679.1\|3924626_3925289_-\|aminodeoxychorismate/anthranilate-synthase-component-II	gnl\|CDD\|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	1.96681e-96
NC_015276.1\|WP_041648935.1\|3942515_3943259_+\|histidine-utilization-repressor	gnl\|CDD\|188194	TIGR02018, Histidine_utilization_repressor, histidine utilization repressor, proteobacterial. This model represents a proteobacterial histidine utilization repressor. It is usually found clustered with the enzymes HutUHIG so that it can regulate its own expression as well. A number of species have several paralogs and may fine-tune the regulation according to levels of degradation intermediates such as urocanate. This family belongs to the larger GntR family of transcriptional regulators. [Energy metabolism, Amino acids and amines, Regulatory functions, DNA interactions].	5.28994e-115
NC_015276.1\|WP_013662683.1\|3927492_3927981_-\|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase	gnl\|CDD\|179953	PRK05174, PRK05174, bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase.	4.15478e-86
NC_015276.1\|WP_041648931.1\|3922862_3923504_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	6.34559e-37
NC_015276.1\|WP_013662687.1\|3931906_3933673_-\|gamma-glutamyltransferase	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	0
NC_015276.1\|WP_013662690.1\|3935162_3936791_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	5.78946e-77
NC_015276.1\|WP_013662695.1\|3940967_3942350_-\|formimidoylglutamate-deiminase	gnl\|CDD\|236420	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated.	0
NC_015276.1\|WP_013662678.1\|3923749_3924517_+\|YdcF-family-protein	gnl\|CDD\|236702	PRK10494, PRK10494, envelope biogenesis factor ElyC.	1.38053e-55
NC_015276.1\|WP_013662681.1\|3926688_3926928_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|366598	pfam01371, Trp_repressor, Trp repressor protein. This protein binds to tryptophan and represses transcription of the Trp operon.	1.42754e-15
NC_015276.1\|WP_013662691.1\|3936782_3937709_-\|histone-deacetylase-family-protein	gnl\|CDD\|212541	cd11599, HDAC_classII_2, Histone deacetylases and histone-like deacetylases, classII. This subfamily includes eukaryotic as well as bacterial Class II histone deacetylase (HDAC) and related proteins. Deacetylases of class II are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues of histones (EC 3.5.1.98) and possibly other proteins to yield deacetylated histones/other proteins. In D. discoideum, where four homologs (HdaA, HdaB, HdaC, HdaD) have been identified, HDAC activity is important for regulating the timing of gene expression during development. Also, inhibition of HDAC activity by trichostatin A is shown to cause hyperacetylation of the histone and a delay in cell aggregation and differentiation.	1.15894e-168
NC_015276.1\|WP_013662680.1\|3925301_3926702_-\|anthranilate-synthase-component-I	gnl\|CDD\|273819	TIGR01820, Anthranilate_synthase_component_1, anthranilate synthase component I, archaeal clade. This model represents an archaeal clade of anthranilate synthase component I enzymes. This enzyme is responsible for the first step of tryptophan biosynthesis from chorismate. The Sulfolobus enzyme has been reported to be part of a gene cluster for Trp biosynthesis [Amino acid biosynthesis, Aromatic amino acid family].	8.12045e-133

>NC_015276.1|WP_013662686.1|3929874_3931158_-|hypothetical-protein
MDPVYFSHGYREREAPFAAHFASLMQQVNFLPSLDPPSEDVNAAKLERHLGYTTGGIAVVANRDTGPSAHILHEVSMCLRARKPLLVFLEDTIPDGLISDRILQYRFSSKSYIREVREHLHAIKLFRSYVGSSPTPRYQSVGRQRSCVLIGMNALSEDYRDGIEHEIQSRGYRLIYFADTGQGIVQPGESHFEIANCSLAICCVDSKSVLDGYLLGVVQDALVPTILLSGKKNSPRNKRVPSEYQRRWVDPKNYEKGISVVTKQINLFEEDFLELDKSSEANTYAHMLALSASATGEYSHDVRTSIIQEVTMGDKYITKGQVGAVGSNAHAHDMNFNQVWQEKNGDIDLEVLAIELSQLRDHLRGIVSLPEHDAAIGAIANAEVAAKEGDGPEAMSWLSKSGKWTLDAATKISLGVATAAIKTSLGV
>NC_015276.1|WP_013662685.1|3928996_3929770_-|hypothetical-protein
MKSKKNYLFYAVVDWLFKKSPVKYFVGCVIGVAGMLASGGLSLDVASGSLKLAYTNELTALSGLVVIICMMVSYGAVRMQMKERYQKIVNEHEKKQLELRGTLEKEMLDIISAKERELEKVKADLELEKVKSANRHKNIGGASKQLLDDIKCLERVFAGLCGSGRLLAKDINGVKLDVYIADAIINQHKYKHVYNADPNLKESWNSMLGKLDASQRAITRAMNGESLDVTPVASAAMSISEFLGKVSDSGHLVLTET
>NC_015276.1|WP_049787792.1|3928061_3928916_-|helix-turn-helix-domain-containing-protein
MTVPLPSFYQPFQPTLTSQGQSHFGIDVQLLKPNESLEGVVYAFVQVKVDQPTVYPIVPDGTNILFFSKCRESFGGTQAKILEVPLATPKGEYFGIWFYPGAIRHVFNVDLAEAKGCIHDLDYLQSPKSPELRFVHERIYEQDSFQGRALLCEHLLTSLLSKNSHFSKFVAYLSHALNLINRAEGTLSVDALAAQVGCSARHLNRVFQLHIGASVKTFSQTIRMNCFLKRRSQRSEGVVLPALHHGIDLGFFDQSHLIKSFKKYGVHSLSPTASDFMSGFYNAK
>NC_015276.1|WP_013662683.1|3927492_3927981_-|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase
MQFSHSDILAMSEGGFFGEGNAQLPSDLMLMVDHIDQLGFTGGHYGRGFLSAQLAIRPDHWFFACHFKGDPVMPGCLGLDALWQLLGVFLGCSGLPGKGRALGVGNVRFSGQIYPDDSRIEYHIHVKRIIKKPLGMGIADGFVLLNDKVIYEAKDLKVGLIR
>NC_015276.1|WP_013662682.1|3927131_3927428_+|antibiotic-biosynthesis-monooxygenase
MPKVIRVFRVEIVPELRIEFEEKFRRISVGALDSQPGCLDITIGFPSPTTPNEYSMISTWESHEKLVEFLGDKWDQALIPDGMEHFAKHYSVHHYTVA
>NC_015276.1|WP_013662681.1|3926688_3926928_-|helix-turn-helix-domain-containing-protein
MQKLIQFLREVENDAQMERKLNALLTPNEVSEMQHRLQIFELLRQGIPQREIAKQLGVGIATVTRGSRAFKELQKNDSV
>NC_015276.1|WP_013662680.1|3925301_3926702_-|anthranilate-synthase-component-I
MTPFKKVPPRIELPRKPKYVTISSNCDFFGLFKKVEKRFENCFMLESLGEDSYISRHSIIGFDPEKQLWAEGNQLFIQERDGATESYESDNPYYLLRSIVPQNIISRGYAGGLTGYIGYDSMNYFEPSLDLQTSDMFDGFRFGLYTDGLILDKMTGEVFYFYYENNRLELVEEMLNAPIPENGALTITPTGDSMSRGDHADAVAKVKEDIIDGKIFQVEVGFKKWFELDGDTIGIYEQLREVNPSPQMYYVKFGEQKVIGASPELLFRLRQGEMETFPLAGTAKRGVDEKEDRDFARVLLNDPKEIAEHNMIVDLHRNDIGRVARFGTVKVRSLMDIKRFSHVQHISSEIVGIIADEHDMFSALASNFPAGTLTGAPKIEAMKIIDDLESDGRGPYGGAVGQFSFNGDCMFAIPIRTVFANGKKAYVQTCGGNVYDSNAADEFEEIQRKFAGTKRVLDQFSPQNEQ
>NC_015276.1|WP_013662679.1|3924626_3925289_-|aminodeoxychorismate/anthranilate-synthase-component-II
MKVYIIDNYDSFTYNLYQYIGEILMGEQSRGDLESFEVVVKRNDEVTLEDLKAAAPDRIIISPGPGSPDNEAYFGVCAQVIRELGKSIPLMGVCLGMQGICHVFGGNVVKAPLPMHGKTSPISHNGEGIFHDIPDQLEIMRYHSLIAESESLPEVLEVTSSVGHLAVEDFDNHDVIHQGGDFEIMGVRHKQYPIQGIQFHPESFATEGGRDLIKNFLLQA
>NC_015276.1|WP_013662678.1|3923749_3924517_+|YdcF-family-protein
MILFYIKKFIGMILMPIPLTLLTLTLALCLLSRFPKLSKCLIILSILLLGLTSWSPVANRLIATVESEYSVFDIAQPVDVVIVLGSGHNEYVNMPAVMQLGRSAIFRLEEGLRILRANPSARLFVSGYGAGGKTPHAEILKQAAIELGIAPTRIITFPLAKDTEDEARMMASFLKDDKERTNNRIALVTEASHLKRAMRFYRNEDINTLPAPAFKLGASESDLRITAAAAYKSQRAFYEWLGLTWQAIKSQILNN
>NC_015276.1|WP_041648931.1|3922862_3923504_-|LysE-family-translocator
MALDTWFTFAFASLALALLPGPTILAVVSYSLSHGKRVSLILVSAVALGDATALFASLVGLGALLSTSAMLFTIVKVIGAVYLLFLGFRMITSRGTSGVNDDAILQRSRRKLFMNTYFITALNPKGIIFFIAFLPQFVIQNGESSSTYAQLWILAVTFVVIASSICAAYALLASSARRLFTSKKVSRRVDIFGGFFMVVAGVWAMFSRRAAIS
>NC_015276.1|WP_013662687.1|3931906_3933673_-|gamma-glutamyltransferase
MNRQTFSSSLTALCAMFAVNNDAWANQAADAVAPEHSSGFHSTQLNISNDWMVTAANPTASQAGADVIQKGGSAIDAMVAIQLMLGLVEPQSSGIGGGAFLVYWDANANKLTTFDGRETAPQAATPRLFQNENGEPLKFYDAVVGGRSVGTPGTLKLLWDTHQKYGKLAWSDLIEPIAKRAESGFEISPRLATLITKDSKRLSRFPETKAYFFDEKGEPKKQGTLLKNPDYAATLRRIAADGADAFYKGEIAQDIIETVQGAPGNPGVLSQIDFDSYQIKERSPVCVAYQQYDVCGMGPPSSGALTVGQILGLTSAFPLNEWGPDAAESWQVLGDASRLAFADRGRYMADEDYVPMPTAGLLDKNYLANRANLITPKTALNSVDAGSPPWQYATTLGDDIAIELPSTSHFNVVDKDGNVVSITTTIENGFGSRLMTNGFLLNNELTDFSFKSHDKEGHPIANRLEPGKRPRSSMSPTIIMKNGKPYMAIGSPGGSRIIGYVAQSIIAHTQWGMDIQSAINLPHILNRFGTMDLEKGTDAERHKAALEAMGFKVNVRDLNSGLHAIRITDDGQLEGAADPRREGTAIGG
>NC_015276.1|WP_013662688.1|3933963_3934326_+|hypothetical-protein
MGIVVCVCMILILLMSIRTPLKRKLDPHKTELAVITLLAGLWNTGWYGFQNLGDYWGNAAFISGLLMMLTSLPLLENHRMLMTLSKHYKKLPPLFNRIALCALCVCAALYAYALILMQFD
>NC_015276.1|WP_013662689.1|3934493_3934805_+|cupin-domain-containing-protein
MKIIRSKEFTADKAWKAIDIANMQGITTRLHWTDQAYKWHVNDGEEVFVVLDGQVEMQYKEGSTIQTTQLNTGDIFFASVGTEHVATPLGEARILVVEKEGSV
>NC_015276.1|WP_013662690.1|3935162_3936791_+|EAL-domain-containing-protein
MVLAKSRHKLFVLSQKLYSRKSLIIIVSCAVSTLITFSLSHFMLQHSEKNGLNRYSNSILQNIQYKKDDIGQILSKPIVSIDNLCSDDDITFLREYLWSHKYIKDVGRIVNDDVACTAGWGKLTTPVQLPTPTKSWPSGSKHWRNVNDMFRDNVRVNLLAYKNTIVVLAPTSYEQNLLKPPHTDLAIATADGQYVFQVVGDLSSNELMEKVKSTNFHQLAIHTCLKDNSICVWAFKKKSGLWAQSDFFLGFLSVIAVLISGGLFQLLNTIYNTRNSMQSRLKRALLHKSLFVVFQPKVNLQDERITGIEALVRWQDEHFGTVPPDEFVTVAEQYQLMPLLSRLVIEKSLQEAGELLKNDSSLHLSINLSMADLSDESLLEFIDLQRSQQGIAKHRLIFEITERSAVGFDQIEQSVDRFVSHGYRISLDDFGTGYANLSWLSKIKAAEIKVDKIFTQSIGKNTTNQNMLSAIFKLVENLELQTVFEGIESKEQADYIVSQNKNAIGQGWLFAKPMKIEELQQFIKTKTSYSESQQKQDDFALT
>NC_015276.1|WP_013662691.1|3936782_3937709_-|histone-deacetylase-family-protein
MTTAYLSHYKCEKHKIDPEHPESPFRLGAIQDRLISGQLLDYLTLIDAQAVELEHLYDTHSRNYVDHIISSAPLEGMIELDAETVMTPHSLNAALYAAGAVVQAVDLVMDKKVENAFCAVRPPGHHAEYAKSMGFCFFNNVAVGAQYAITHHGLERIAIVDFDVHHGNGTEDIFQGNRNVLFASSYQHPFYPYSDPGESHDNIIHIPLEAGTNGETFRMAMSNQLLSALDAFRPELIMISAGFDAHKEDSLGQLRLGADDYAWITDQLVVAADKHCDGKIVSVLEGGYHLDALGRAAFQHIRSLMKLR
>NC_015276.1|WP_013662692.1|3937886_3940325_+|GNAT-family-N-acetyltransferase
MTQHALHTLFSPHSVIALTGKNPNDPLMLALLSHLCAPSTDKRKSFNKITLVGCLPNGDNLTSYPHSESLSALSSQGSNTSDTLAILCSQLDKSLENTIKECSEAGINALLMLTWVPDSPAHIQRLLRRYNMRLLGPNSFGVCTPSRGFNAWLGLTSPISGRLALLSQSGTIASAVVDWATWQGIGFSHVVATGTPIDVMPHQVMDYLSNDFQTQSILMYIQNVGNPTRFLSSLRSTSRSKPVAVVTEHSLGADDRVLDAALSRTGAVRGHRLNDLVAAASVMTNARRVQEGSLIIIGNGAGPGELAAQKAQELNVDLLTPSLELQTRLESVMDNRGSIGSVTTVWASCPTDLFIDLAETALSDHHCGAVLLMLSPTALIDLQSLQEQVVQLHKKQRKLVMVCLMGGGHIVDLRTRINEASIPTFRTPETAIEGYQFLELFQRNQKLAKQSPDSHAFRFQVDVNQARQHIQERLTQGMTDLSHRDLEHLFTLFHIAISPSPQHSLLSTPISLRVFQDATFGPVIALSFGGSHHSSKYVEAVGLPPLNTILAKDLIARALPNTECFELEALLRNLSSMVCELPELLELHLMEVAIHEDGSISTNASASITPRPDLRRYEHLAIQPYPRQWLSEAKLNSTTTTTIRPVLPRDAWMMAEFVKNLSHESRYFRFIANISELTPKMLANMTHIDYDREMALLAVIEQNNESKLIGAARYIDNFDDKSCEFAVVIGDDYQGLGLASYLMRKLFIIANDKGLRIMKGIVLSENVHMIEFCKRLGFSIQRDPDDYSQVIATVKLTDELIENSTNKLKKLD
>NC_015276.1|WP_013662693.1|3940330_3940636_-|NIPSNAP-family-protein
MVTCYVKYVVDPYKLDEFETYAKLWIPLVNKFGGHHSGYFLPSEGASNIALALFSFPSLAEYERYRTDSMQDAQCIAAFEYAEKTKCIISYERSFFRPVFE
>NC_015276.1|WP_013662694.1|3940636_3940861_-|hypothetical-protein
MRASLREKVIQVCEKKIAQKGETVGVSFYAFFANKNDDPALLMEAATWWIQTHKLDHFEKAKKILTLVGEREQL
>NC_015276.1|WP_013662695.1|3940967_3942350_-|formimidoylglutamate-deiminase
MTQFFAKRAYVSLSNTNDVYQWKNDVAFTVEQGKITAIEVDVEKNDSMKVLEGPVLPTASNLHSHAFQRLMAGMAEVALNPEDSFWSWRDVMYKTVSTLLPEEVEVIASKLYIELLKGGFTQVGEFHYVHNVPEGGAYPESTCLGEAILRAGDRTKMGVTLLPALYQYAGFGELPPNDGQVRFVQSTDAYIDQYRAYQHLIKDSDRHRLGICFHSLRATNFNAMKQVLGTLDGGQPIHIHIAEQTKEVEDCLDYSGRRPVEWLLSEFDVNAQWCLIHATHLNETEVEGIANSGASVGICTTTEANLGDGFFPATEYEAAGGVWGVGSDSHVSTSLQEELRWLEYGQRLQHQKRNRLYGESQPYIGDHLFAMSKRGGDQACGVQTGLSIGARADFMVWSTAEPFVSASQSKDLLNRWLFGLSSNVIKDVYVAGECVIDNYQHELDGRINDAFNEIVARRFR
>NC_015276.1|WP_041648935.1|3942515_3943259_+|histidine-utilization-repressor
MNPLLHDLFAHIPDTPQPIYARLKQAIAHKIASGEWQANQRVPSEAEMVTAIGVSRMTVNRALRELTAEGILTRQQGLGTFVAPQKAHSALFEVHNISEEVASRGGVYRAEKILLERRKATMEEAVNLGMRANQEIFCSVILHFENDLPIQLEERVVNAHLAPEYGNQDYTKQTPYVYLMKAAPMTEGEHLVEAVLPTQEECELLNVDATEPCLQIKRRTWSSDQIVTTARLLHPGSRFQLFGHFSN

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Crispr_ID: NC_015276_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_9

4070916-4071014

Orphan

Consensus_repeat	Method
CCATAAACCTAGCACCAGACAAAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015276_9

>merge|NC_015276|9|4070916-4071014|CRISPRCasFinder
CCATAAACCTAGCACCAGACAAATTCGCGCCAGTCAAATCCGCTTTAGACAAATACGCGCCAGATAAATTTGCTACCATAAAGCTAGCACCAGACAAAT

>NC_015276|9|8|4070916-4071014|CRISPRCasFinder
CCATAAACCTAGCACCAGACAAAT	TCGCGCCAGTCAAATCCGCTTTAGACAAATACGCGCCAGATAAATTTGCTA
CCATAAAGCTAGCACCAGACAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013662792.1\|4064102_4064507_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|374224
NC_015276.1\|WP_013662797.1\|4067271_4067895_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662804.1\|4072903_4073446_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662808.1\|4077006_4077258_-\|YfhL-family-4Fe-4S-dicluster-ferredoxin	unknown	unknown	gnl\|CDD\|274938
NC_015276.1\|WP_148231055.1\|4065653_4066169_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662806.1\|4075153_4076254_+\|potassium-channel-protein	unknown	unknown	gnl\|CDD\|369572
NC_015276.1\|WP_190273409.1\|4065239_4065452_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662809.1\|4077317_4077806_-\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NC_015276.1\|WP_013662800.1\|4069001_4069508_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662803.1\|4071779_4072862_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_148231056.1\|4068494_4068722_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662805.1\|4074671_4075145_+\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|223297
NC_015276.1\|WP_013662799.1\|4068367_4068517_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182915
NC_015276.1\|WP_013662798.1\|4067904_4068309_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662796.1\|4066369_4067233_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662810.1\|4077962_4078505_-\|YggT-family-protein	unknown	unknown	gnl\|CDD\|376765
NC_015276.1\|WP_013662811.1\|4078514_4079336_-\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
NC_015276.1\|WP_013662807.1\|4076346_4076886_-\|DUF924-domain-containing-protein	unknown	unknown	gnl\|CDD\|377592
NC_015276.1\|WP_013662801.1\|4069632_4070583_-\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_083799816.1\|4073695_4074097_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|222904

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013662808.1\|4077006_4077258_-\|YfhL-family-4Fe-4S-dicluster-ferredoxin	gnl\|CDD\|274938	TIGR04041, glycine_radical_enzyme_activase_YjjW_family, glycine radical enzyme activase, YjjW family. Members of this family are radical SAM enzymes, designated YjjW in E. coli, that are paired with and appear to activate a glycyl radical enzyme of unknown function, designated YjjI. This activase and its target are found in Clostridial species as well as E. coli and cousins. Members of this family may be misannotated as pyruvate formate lyase activating enzyme. [Protein fate, Protein modification and repair].	4.93765e-08
NC_015276.1\|WP_013662792.1\|4064102_4064507_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	5.29459e-64
NC_015276.1\|WP_013662799.1\|4068367_4068517_-\|hypothetical-protein	gnl\|CDD\|182915	PRK11032, PRK11032, zinc ribbon-containing protein.	0.00981094
NC_015276.1\|WP_013662806.1\|4075153_4076254_+\|potassium-channel-protein	gnl\|CDD\|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	1.1278e-10
NC_015276.1\|WP_013662809.1\|4077317_4077806_-\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	6.41826e-89
NC_015276.1\|WP_013662810.1\|4077962_4078505_-\|YggT-family-protein	gnl\|CDD\|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	5.51153e-11
NC_015276.1\|WP_013662811.1\|4078514_4079336_-\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	1.48819e-104
NC_015276.1\|WP_013662807.1\|4076346_4076886_-\|DUF924-domain-containing-protein	gnl\|CDD\|377592	pfam06041, DUF924, Bacterial protein of unknown function (DUF924). This family consists of several hypothetical bacterial proteins of unknown function. Structurally, this family resembles TPR-like repeats.	1.16324e-90
NC_015276.1\|WP_013662805.1\|4074671_4075145_+\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.46615e-87
NC_015276.1\|WP_083799816.1\|4073695_4074097_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|222904	PHA02601, int, integrase; Provisional.	8.51951e-29

>NC_015276.1|WP_013662801.1|4069632_4070583_-|hypothetical-protein
MAHDKTLTELKWFKWALWGPIGTGVLVATAIGIADFTNEDLRVCFTSACVNDAIGRLKFPLAIASLAFPLVALVASHHRSVQTAAQISRSDKQIEATDKKNSFENCIKHRGIFMDFLSDIEKREKIKFISKEHIYTDIFAQNDYTYFSYYCDDMQASGDPSILDDGLVSYENFFHKIYFHLVSLNDFWDEDYIMPDRKPYAFKDNMYSFSRLVFPDYYVGERLSFDYSSIEGRLQNDYYLMLSILDTLEYFCLSKKYLDDKCNVFNKLKSDFYDRLHGYSQHLTTERVKVRAILNDKGETTGFEQILDDDDELIPF
>NC_015276.1|WP_013662800.1|4069001_4069508_+|hypothetical-protein
MREAAGGCLVFIVLAAIVLLFMKSCGGDSQEELVESLAPNAQDYVVLASEEYATPSDKKGLKFTIYSEDSYTFEKRGQTLIKAAYDLLEDKDLYEVVIRLSALPSIKPKYIHAGLINYHPHKEDTWGNKKEYIWNVTASPNKIIDGQLEEDGKLYPLKYMAVKSYLKK
>NC_015276.1|WP_148231056.1|4068494_4068722_-|hypothetical-protein
MLRGELRRSALDSRCRAVQINLEYYSTEWMVCELLRRDWRLVEHNGETLGPTCPACVQQHKEELQEAPHVQDETH
>NC_015276.1|WP_013662799.1|4068367_4068517_-|hypothetical-protein
MFKTKPIDKDAVFRQMRIVIVCEECHTEGYFYDAEGDVLCPHCIKKLVS
>NC_015276.1|WP_013662798.1|4067904_4068309_+|hypothetical-protein
METIADLSLYIDSNIKFSLFFKFMLILSFFEVAFILGCNIIIWSAYLIKVVFSILFRKEIYNQTPPSISLAPLAYKFLSKVASGSMDILRRYELHKNQEKTEEPLREHLKDIKKSNLEAEMLSEEKTNKSSDIS
>NC_015276.1|WP_013662797.1|4067271_4067895_+|hypothetical-protein
MLDTHCSENKPVYLSRRRSFSDSSTTSGLKETFEHIQRSNNVIPIKGDISIRYYHCEALEICQTYLRRNSTFSSVKDSDLFKTSIHKIFELAEFKKAILDQKINKRKKHTLYNIELFEMNSKNKTNRFVNCSRLRRGDIKELFPSTNKPTTYKLNKYEKIKFDLLSDFFDYSDAHEASINLIVIFTSLLREEDRNLFAYNYKSILQT
>NC_015276.1|WP_013662796.1|4066369_4067233_+|hypothetical-protein
MNSRKNTNTATKFIFDNFNAMDSIKDIEHFINEVVHNTLIHKRLHSKYPLSILSEDDLDSRLFPKSIMRIARKHQQIITHSFQDTKCTYKHHSTHQIFLSIIEKIFFTDAIIRKAPIRVAEKESKKKIELIRHLLAKSISKELITMDFIGEDQLLYSSALLSILSKCPSYLDTRNELKLSADVAIKTKKGHTSNILKRENTIHLIDDIRISNVNALQLMGATQQKNMERDILDILQSNKTIMASDPRAVHVELEMPDKNLSCFMVSYHDTSMTPLDYYPFKVVIKDR
>NC_015276.1|WP_148231055.1|4065653_4066169_+|hypothetical-protein
MTALDNYGEGANVLNAHVQSRLASFMEDMQIASTAKMIDSYISGTPASCVNINTIAGSLAGATDTLLDSTNDLLTELDQGITNYDASTLPLNKFEALLDRVSNTLEANAATILGTISNETQELAKMYETHKKMAMVMAVPALIKDDCIRPLLVRVAGAELIPLLTDEMKFF
>NC_015276.1|WP_190273409.1|4065239_4065452_+|hypothetical-protein
MIAHSNDVSGGIDGLFVKDLYCHCHNPDCCASFVVRAAHTHYLQPPRNSVLDMAKALVKKHEEQLELGGI
>NC_015276.1|WP_013662792.1|4064102_4064507_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MKYPIVLHTDDGDSYSVTVPDVPGCFSAGTTLNEAIDMAEEAIFFHLEGMLEDGEDVPVASEIAVYKDNPDFADGIWAVASVDITPLLGKSEKINVTLPHLLISKIDKAVASNPQYKNRSAFLAQVSRKELKLA
>NC_015276.1|WP_013662803.1|4071779_4072862_+|hypothetical-protein
MAQANFEYEAIRYLVDKCGLYESVYQGEQQVMVRNSSPLCLDIKELLAEIKKWAIDSGKAFGNTCPNGMSLSNRVFCYDITEYNGTYLAAFWNEVPKGKRGVGTLPKDKPVKDQVPSNAKISPSDIPGYMTYFLFAPKYNNMFLPIKLRQPGETANNLATSNMKQYLLNYIRDHSEYRIKSENGSYTFSDKPRGTKNRLPHSSLTPRLDWTKVKDDADLETVFANASSVTKLTYKFNQPDKIKSKANKRLFSIKQAVQDVKDHDKHLDPRREIEMIIPVTGISKQELDELVRDFEEYDKTQAFNVGFKLQKDSREYWLDKTYRKKDGRLMVMVQPKNNDFPILKDLHQKLFSELENFLAS
>NC_015276.1|WP_013662804.1|4072903_4073446_+|hypothetical-protein
MTNFIVQLLASEKGVAWLSGLSWVVIFGAAILSFLPGMDVQAMDLISISNSMITISAIIFGIMGAWLSLVKVEYREQIKEKVPKRENVQDILNKAENLSGIITTSCVILFICIIYNFAYYVFSNYAFFQSIKSELKGLSLSVLVFLGGIQIRLLIAIMWSGVDHVLDLYSLKDQLEDERD
>NC_015276.1|WP_083799816.1|4073695_4074097_+|tyrosine-type-recombinase/integrase
MIKSDRSRPNFGHMFAGSCSRAFRSAIADAEIFLPRGQLTHVMRHTFAVHFMRDKGSIFDLQKILGHKTLKMTLRYAKFHPDYLTDAIHKNPTRFNAARRDRNRSLIIWTLLDTAHSRSGSEKNVLRVIISLS
>NC_015276.1|WP_013662805.1|4074671_4075145_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MLHIVLYQPEIPPNTGNVIRLCANTGYQLHLIEPFGFDLDDKKLRRAGLDYHEFTHVKKYANWDAFIAQNENIGTLYALTTKGSRTHSEAEFKENDVLVFGPETRGLPAEFIEALPKPQRLRLPMQADSRSLNLSNTVAVMVYESWRQLDYKMSSTD
>NC_015276.1|WP_013662806.1|4075153_4076254_+|potassium-channel-protein
MNSLGLFLKKKSHGRQRYKKIVYQHAIKDLRRRFVMLAAIIVIHSIAMVFFEDLNWWQAFWLTMTSASTTGYGDISAATFWGQLTTIVLIYGLGITLLAQIASDYVELRLIQRDMRVKGKMEWSTMRDHLLIINTPALHTERYLKLLITQISNTPELEDTPIQILTPHFPDGLPEELREMGVVHHTGDATEPGKLESAGVDKAKYIIVLSPDSQNDHSDSIVFDTLHRVHETGASAFLLAEAVNDLNRDRFRKAGANAVIRPIRAYPEMLVRSLIAPGTEQVLENLFRYQGDHTVRIDVNLSNVTWAEIVTRLIQENIGTALGYENEFGNIVTHPDTHASITARSLIVLVGDDTNLPSGSKIKALF
>NC_015276.1|WP_013662807.1|4076346_4076886_-|DUF924-domain-containing-protein
MLANDVIELWFESCTPEQWYKKDVEFDRKLTELFGEVLEKAAKGELYLWRSSAIGRLAEIIVLDQFSRNIYRDTPRAFSQDPMALVLAQEAVSLALDQQLPLIQRSFLYMPYMHSESLVIHDEAMRLFSQPGLEHNYEFELKHKVIIERFGRYPHRNALLGRPSSLEEAAFLSEPDSSF
>NC_015276.1|WP_013662808.1|4077006_4077258_-|YfhL-family-4Fe-4S-dicluster-ferredoxin
MSLIITDECINCDVCEPECPNEAISQGEEIYVIDPAKCTECVGHYDEPQCVQVCPVDCIPKDKDYVETEEELMEKYLVLTGQL
>NC_015276.1|WP_013662809.1|4077317_4077806_-|pantetheine-phosphate-adenylyltransferase
MSTIAVYPGTFDPITNGHADLVERAAKLFSKVIVAVAASPKKRPALSHDLRIELAENVLGHLHNVEVVGFDNLLTEFTRSVNGQVVVRGLRAVSDFEYEFQLANMNRVIAPDVESLFLTPSEKHSYISSTLVREIASLDGDFGQFVHPEVEKVLKEHYQNAK
>NC_015276.1|WP_013662810.1|4077962_4078505_-|YggT-family-protein
MGGDPFILVVKTLGSLYLFVVMLRLLLQLSRADFYNPISQAIVKATSPILLPLRKVIPPIGRLDTASVVLALAVQFAMVFLILMIAGFNSTPAHYVIYTIAGLFYNLLQLYFWAVIITVILSWIAPHADHPGAMIVRQICEPLYRACHKVLPSLGGLDLSPIFIFLAITILQNFIRPYVI
>NC_015276.1|WP_013662811.1|4078514_4079336_-|pyrroline-5-carboxylate-reductase
MSLRIAFIGVGNMASAIIGGLVSSGYPSDKICGTSLNTDSFAALEEKFGLTMMTSNTDAIAAADVVFLCVKPNQVRSVLEQAAEVITPRQMFVSVAAGVEIGSIESWLPVSAAVVRSMPNTPALVNCGASGLVANTVASVEQKEWISTVFKSFGDCVWVNNEEQMHQVTALSGSAPAYFFRVLESMIKSGVDQGMTEEDSRKLASLTMLGAAKMATELDESIAQLRINITSPNGTTEQALNSLNDANIDKVMDDAMRACVKRSKELAEEMAKS

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Crispr_ID: NC_015276_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015276_10

4118177-4118290

Orphan

Consensus_repeat	Method
AGGAGCAGATGGCAGATCATTTAATGTACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015276_10

>merge|NC_015276|10|4118177-4118290|CRISPRCasFinder
AGGAGCAGATGGCAGATCATTTAATGTACTTTTTTCTTAGCAATGAGAGAGCTATAACCCCCTCCCAACCCCTTAGTAAGGAGAAGGAGTAGATGGCAGATCATTTAATGTACT

>NC_015276|10|9|4118177-4118290|CRISPRCasFinder
AGGAGCAGATGGCAGATCATTTAATGTACT	TTTTTCTTAGCAATGAGAGAGCTATAACCCCCTCCCAACCCCTTAGTAAGGAGA
AGGAGTAGATGGCAGATCATTTAATGTACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015276.1\|WP_013662841.1\|4109589_4110153_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|129813
NC_015276.1\|WP_013662853.1\|4121756_4122653_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_015276.1\|WP_013662859.1\|4127626_4128406_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662847.1\|4116231_4116783_+\|ATP-dependent-protease-subunit-HslV	unknown	unknown	gnl\|CDD\|235477
NC_015276.1\|WP_013662843.1\|4111895_4112690_-\|thermonuclease-family-protein	unknown	unknown	gnl\|CDD\|214615
NC_015276.1\|WP_148231134.1\|4126088_4126706_+\|hypothetical-protein	unknown	unknown	unknown
NC_015276.1\|WP_013662852.1\|4120659_4121637_-\|asparaginase	unknown	unknown	gnl\|CDD\|199207
NC_015276.1\|WP_013662842.1\|4110389_4111658_-\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|235976
NC_015276.1\|WP_013662848.1\|4116814_4118140_+\|ATP-dependent-protease-ATPase-subunit-HslU	unknown	unknown	gnl\|CDD\|235364
NC_015276.1\|WP_013662854.1\|4122813_4124547_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|223097
NC_015276.1\|WP_013662845.1\|4113169_4115401_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514
NC_015276.1\|WP_013662851.1\|4119387_4120596_-\|L-2-hydroxyglutarate-oxidase	unknown	unknown	gnl\|CDD\|183292
NC_015276.1\|WP_013662846.1\|4115459_4116092_+\|SPOR-domain-containing-protein	unknown	unknown	gnl\|CDD\|335993
NC_015276.1\|WP_013662849.1\|4118369_4118747_+\|DUF971-domain-containing-protein	unknown	unknown	gnl\|CDD\|226066
NC_015276.1\|WP_013662858.1\|4126763_4127543_+\|toll/interleukin-1-receptor-domain-containing-protein	unknown	unknown	gnl\|CDD\|379328
NC_015276.1\|WP_013662844.1\|4112698_4112914_-\|50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234576
NC_015276.1\|WP_013662850.1\|4118764_4119391_+\|SCP2-sterol-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225706
NC_015276.1\|WP_013662838.1\|4107799_4109023_-\|quorum-sensing-autoinducer-CAI-1-synthase	unknown	unknown	gnl\|CDD\|180866
NC_015276.1\|WP_013662837.1\|4106697_4107732_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|381085
NC_015276.1\|WP_013662856.1\|4125485_4125968_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350373

Protein	Function_ID	Function_description	E-value
NC_015276.1\|WP_013662841.1\|4109589_4110153_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	4.77631e-59
NC_015276.1\|WP_013662853.1\|4121756_4122653_-\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	7.52264e-12
NC_015276.1\|WP_013662847.1\|4116231_4116783_+\|ATP-dependent-protease-subunit-HslV	gnl\|CDD\|235477	PRK05456, PRK05456, ATP-dependent protease subunit HslV.	3.33068e-126
NC_015276.1\|WP_013662843.1\|4111895_4112690_-\|thermonuclease-family-protein	gnl\|CDD\|214615	smart00318, SNc, Staphylococcal nuclease homologues.	7.45949e-21
NC_015276.1\|WP_013662852.1\|4120659_4121637_-\|asparaginase	gnl\|CDD\|199207	cd08963, L-asparaginase_I, Type I (cytosolic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type I L-asparaginases, which are highly specific for asparagine and localized in the cytosol. Type I L-asparaginase acts as a dimer. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase. One example of an enzyme with no L-glutaminase activity is the type I L-asparaginase from Wolinella succinogenes.	3.10811e-109
NC_015276.1\|WP_013662842.1\|4110389_4111658_-\|malate-dehydrogenase	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NC_015276.1\|WP_013662848.1\|4116814_4118140_+\|ATP-dependent-protease-ATPase-subunit-HslU	gnl\|CDD\|235364	PRK05201, hslU, ATP-dependent protease ATPase subunit HslU.	0
NC_015276.1\|WP_013662854.1\|4122813_4124547_-\|arginine--tRNA-ligase	gnl\|CDD\|223097	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	0
NC_015276.1\|WP_013662845.1\|4113169_4115401_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NC_015276.1\|WP_013662851.1\|4119387_4120596_-\|L-2-hydroxyglutarate-oxidase	gnl\|CDD\|183292	PRK11728, PRK11728, L-2-hydroxyglutarate oxidase.	0
NC_015276.1\|WP_013662846.1\|4115459_4116092_+\|SPOR-domain-containing-protein	gnl\|CDD\|335993	pfam05036, SPOR, Sporulation related domain. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.	1.16561e-12
NC_015276.1\|WP_013662849.1\|4118369_4118747_+\|DUF971-domain-containing-protein	gnl\|CDD\|226066	COG3536, COG3536, Uncharacterized protein conserved in bacteria [Function unknown].	6.44074e-52
NC_015276.1\|WP_013662858.1\|4126763_4127543_+\|toll/interleukin-1-receptor-domain-containing-protein	gnl\|CDD\|379328	pfam13676, TIR_2, TIR domain. This is a family of bacterial Toll-like receptors.	3.93665e-20
NC_015276.1\|WP_013662844.1\|4112698_4112914_-\|50S-ribosomal-protein-L31	gnl\|CDD\|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	1.71237e-39
NC_015276.1\|WP_013662850.1\|4118764_4119391_+\|SCP2-sterol-binding-domain-containing-protein	gnl\|CDD\|225706	COG3165, COG3165, Uncharacterized protein conserved in bacteria [Function unknown].	3.1985e-16
NC_015276.1\|WP_013662838.1\|4107799_4109023_-\|quorum-sensing-autoinducer-CAI-1-synthase	gnl\|CDD\|180866	PRK07179, PRK07179, quorum-sensing autoinducer synthase.	0
NC_015276.1\|WP_013662837.1\|4106697_4107732_+\|response-regulator-transcription-factor	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	2.30907e-06
NC_015276.1\|WP_013662856.1\|4125485_4125968_+\|hypothetical-protein	gnl\|CDD\|350373	cd14523, DSP_DUSP19, dual specificity phosphatase domain of dual specificity protein phosphatase 19. Dual specificity protein phosphatase 19 (DUSP19), also called low molecular weight dual specificity phosphatase 3 (LMW-DSP3) or stress-activated protein kinase (SAPK) pathway-regulating phosphatase 1 (SKRP1), functions as a protein-serine/threonine phosphatase (EC 3.1.3.16) and a protein-tyrosine-phosphatase (EC 3.1.3.48). It is an atypical DUSP; it contains the catalytic dual specificity phosphatase domain but lacks the N-terminal Cdc25/rhodanese-like domain that is present in typical DUSPs or MKPs. DUSP19 interacts with the MAPK kinase MKK7, a JNK activator, and inactivates the JNK MAPK pathway.	0.000509223

>NC_015276.1|WP_013662848.1|4116814_4118140_+|ATP-dependent-protease-ATPase-subunit-HslU
MSKMTPRETVNALDQHIIGQQSAKRAVAIALRNRWRRMQLPEDMRAEVTPKNILMIGPTGVGKTEIARRLAKLSNAPFIKIEATKFTEVGYVGRDVESIIRDLVEMAIKMLREQETTRMRHKAEDAAEDRILDALLPPARGGDPELNNESNTRQIFRKKLREGQLDDKEIDIDVSETPVGVEIMAPPGMEEMTSQLQNMFSSMGNDRKKRRKLKVKDALRQVRDEEAAKLVNEDELKARAVEAVEQNGIVFLDEIDKVAKSGERSSGEVSREGVQRDLLPLVEGCTVNTKYGMIKTDHILFIASGAFHLTKPSDLIPELQGRLPIRVELDALTVEDFKRILVEPSASLTKQYVALAKTENIDINFTDEGITRIAEIACQVNETVENIGARRLHTVLERLLEEVSYSASDMPDDQQVNITAEYVDEQLGEVVKDEDLSQYIL
>NC_015276.1|WP_013662847.1|4116231_4116783_+|ATP-dependent-protease-subunit-HslV
MTTILTVRKENEVVVGGDGQVSLGNTVMKGNARKVRRLYKGEVIAGFAGGTADAFTLFERFEGQLEKHQGHLVRAAVDLAKDWRSDKALRKLEAMLVVANKENTLIITGTGDVVEPQHGALAIGSGGNYAEAAARALIDNTDLSAKDIVEKSLNIAADICVFTNHNLTIETIAIDPALEDQTN
>NC_015276.1|WP_013662846.1|4115459_4116092_+|SPOR-domain-containing-protein
MAAKGSRPRKGATRKAATPPPKRKTSWWMWLIVPAIVFGFIYGLMQLSQVEQTTKPQTQVKTQAPTKSTSTPAKAEQKPKVVESQKKPVETAKRAEKDKFEFYQILQDSEVDTSHVDAYEYEPRGEQDFLYMLQAASFRSSTDADRLRAELILSGLPAAIRETTGENGAPWYRVTVGPYLSRSEKSRAQDKLVAKGIESYTYKIPRPEGK
>NC_015276.1|WP_013662845.1|4113169_4115401_+|primosomal-protein-N'
MQETLLTTQPYIKVALPVPMRRTFDYKVPKAIAVRHILQPGMRVKVPFGKSQRIGIIESLASESDWDDAQIKPLSALLDDAPVLDTEILSICEWAARYYHHPIGEVLFHALPVLLRKGESADFRTETWWFPSETGLKTPLDELKRAPRQVEFLKAVQQHENGLSQQVVSTLGLAPAAGKSLEEKGLVYREQRQFLKMAETHAHQKQVPPILNDEQQVATDHIIHNTGTFHVSLLDGITGSGKTEVFLRVIDKLIKEDKQVLVMVPEIGLTPQTLKRFENRLDTDIVLMHSNMTDRERLDAWLLCRQGHAKVIIGTRSAVFMPIKNLGMIIIDEEHDASYKQQDGFRYHARDLAIKQAQSANAPVLLASATPSFESLNNARQQKFAWLKLRKRAGSAQMPTIERVDLRGQTLVHGLSEYTLETMKQCLARKEQVLVFLNRRGFAPTLMCHECGWIAACDHCDVNMTVHRKANKLHCHHCDHHKALIFECPECHSRELFTVGEGTEQVEAALIPLFKDTPILRIDRDSTQRKSALTQITQKIHEHDQAILVGTQMLAKGHHFPNVTLVVVMDADAGLFSADFRGMERTAQLITQVSGRAGRASKPGQVLLQTYHPDHEAIECLCERSYEEFALEGLQERADLALPPFYHQIIVRAESADEWEATQFLTHLREMLMPYCEAGIGFVGPYSAIIVRKAGQHRALLSIKSPKRGNLHRLAAIASQWLEQEFRSRKIRFAIDVDPLETY
>NC_015276.1|WP_013662844.1|4112698_4112914_-|50S-ribosomal-protein-L31
MQKEIHPNYTTVTATCTCGNTLTLNSTLGKDLHIDVCSQCHPFYTGQQKMLDTGGRVDRFNKRFGARRSTK
>NC_015276.1|WP_013662843.1|4111895_4112690_-|thermonuclease-family-protein
MKHCFLKKRQFILALFLCLFALESFGQTVTIEPLCRANGSVKLASVKRVVDGDTVYFQDGRKVRLVGVNTPELDHKHGLHEPFAMEATLYLKSLIGKEVYWQSALNDRDRYGRKLYYLFDKDRISIASRLLSAGLGYRIAIPPNTKYQDCLIQSERKARNAHHGLWRAPHNWQPKAGFTKVSVTITSITRNRGGWWLETNQDLVINLPRLISELWSEQDVYSLKNKRIEARGWQHQRNSQSKRFKSWVLIVKHPNDLLDVSSDA
>NC_015276.1|WP_013662842.1|4110389_4111658_-|malate-dehydrogenase
MAEDLKQAALEYHENPVPGKLNITISKPTATARDLSLAYSPGVAEPCREIAKDPETAYRYTGKGNLVAVISDGSAVLGLGNIGPLASKPVMEGKGVLFKRFAGVNSVDVEVESESPQAFIDTVARIANTYGGINLEDIKAPECFEIERELIERCNIPVFHDDQHGTAIVTAAGLLNALELQEKNIADAKIVCLGAGAAATACMKLIIACGAQSENIYVLDRKGVIHSGRDDLNKYKSMFAIDTDARTLDDAIDGADVFIGVSGPDLLSGDQLKKMAPKPVVFACSNPDPEISPEVAHSVRDDLIMATGRSDYPNQVNNVLGFPFIFRGALDVRATKINEEMKVAAVNALKDLAKEPAPQDVIDAYGGGALEFGKEYILPKPMDSRLLTEVSGAVAKAAVDSGVASLPYPDFYPLESLDRFEA
>NC_015276.1|WP_013662841.1|4109589_4110153_-|TIGR00730-family-Rossman-fold-protein
MKVAVFCGSSLGHSKVYERAVAELGAFFAENGIEVVYGGGHVGLMGVIANAVLAAGGKVTGVIPTHLEQREIAHPSLTELHVVTDMHERKAKMADLADAFVALPGGVGTLEEIFEVYTWAQIGLHKKPCAFYNVDGYYDLMFEMIVSMHREGFVKKPYVDMLIKESQPEGLLRAFEDYVAPQEKWNS
>NC_015276.1|WP_013662838.1|4107799_4109023_-|quorum-sensing-autoinducer-CAI-1-synthase
MSVNSKSYPRYLEEKVRQHELRRAALNGRNILHGLTPTASSIQLISNDYLRLAGHPEVRYAQKKVLENEDNLVLMSSAFMHGDNPQIFFEERMATFLDAEETVLCQSGYSANVGLIQAILEDTDTPVYIDMMAHMSLWDGAKFSGAKIQPFRHNNVDQLMYLINKNGPGLVIVDSIYSTNGSVCPLQELVDAAYDKGCVLLVDESHSLGTHGPYGRGMVVQYGLQNKVMFRTASLAKAFAGRAGLVTCPTGFGDYFKCTSKPSIFSSALLPYEIAGLDMTLNLILESDYKREKLRKNASFLRQSLEGLGYNTDHSASQIIALESGTEWQTMILKDALENRGVFGSVFLAPATAKNRALVRFSVNADLTDAQLVKIIQVCEEIREEVDFLQWRSTRKRKVPRAEAVLV
>NC_015276.1|WP_013662837.1|4106697_4107732_+|response-regulator-transcription-factor
MLKPKKKVINAYYHPTTAVFLDDHRAFLNSVPLALEDDIAYQAFSTPHNALEYINNHTCHDSLIQKNDFITDGSKAHHYTLNAAIIESKARFNERFAEPSVLITDYALSGYDLNGLEVCESIKHPNVKKVLLTGVADEQIAIEALNNKVIDYYIKKSSPDVFKLVNQLIHQYQQDYIRETTQVIHESLKLSKPLIEDPAIIEYFYSILKQHHTFEYQVLIESTASSLDFLLLDESAQVKRLLVLDPDDLAVHVEVAQDAHADDELLDELRSGNKIPFFPTADGFYHPDIKKEWENYLHPCVEIVGEKATYLAAFIANPDDRFTSIPAAEITSFHDYLQTVGTHV
>NC_015276.1|WP_013662849.1|4118369_4118747_+|DUF971-domain-containing-protein
MLTPTKIHYHKKSRELELVFSDNQAFRLSAEYLRVHSPSAEVRGHGQQLPILQFGKKDVAIQNIEAAGNYALKITFDDGHDTGLYSWEYLYNIGKNQEELWQMYLSRLEKEGKTRDTSVIQIHQL
>NC_015276.1|WP_013662850.1|4118764_4119391_+|SCP2-sterol-binding-domain-containing-protein
MESISLSALSAIEKAINLALEQDSPSLERLTKLSGQQIFLEVDDFNLILQVHIHETGVMLFKPESMEEVELDPKLDTHVKGPSSAYRKLLEGDGFFDGDLRIQGNAQALMTLHKVLENFELDWEGILADYIGDLPASTLARLLRYQWGITKEVSTQARIQLVNHLQSNSQLLPSKIEFDHLVDDLERFGVQLDRFEAKLRLSERKKNS
>NC_015276.1|WP_013662851.1|4119387_4120596_-|L-2-hydroxyglutarate-oxidase
MTYDYIVIGGGIVGVSTAWQLQQRFPDKKVLLLEKEAVFSKHQTGHNSGVIHAGVYYAPGSLKATFCKAGVQATISFCEENDIPYNQCGKLLVATTPLEVERMQALFERCQQNEIDVELLSADQLKKREPNIQGLGAIYVKSTAIVNYQEVTTKMAKCFTDIGGEARLKHDVVELQEYDDLITVGAIHQGCEVEYQGKFLVTCSGLMADRTTKMLGIKTDFQIIPYRGEYYQLPEKYNNLVNHLIYPIPDPDLPFLGVHLTRMIDGSVTVGPNAVQGWKREGYGRINIDLRDIFDMITFPGFWRVTKKHFRSGLVETKNSLWKPGYLKLVQKYCPQITVDDLKRYPAGIRAQAVMRDGTLVHDFLFAESPRSLHVCNAPSPAATSAIPIGEYIVDKVEDKQV
>NC_015276.1|WP_013662852.1|4120659_4121637_-|asparaginase
MKIYIAYTGGTIGMKESDDGLIPDPDFAEVLQKQLEEVTAKSDVKNEYCVYRYPELIDSSNATPEEWRKIALDVSTRWDDFDAFIVLHGTDTMAYTSSALYYMLENASKPVVVTGSQVPMFQARTDGLNNVLGAISACNEGKHGVSLFFGSLLIAGNRAHKANTTDWQAFSSPNYPVLGTLGIDWVWTPLTSEHQDMTERLPEMQAGAVTLLPVFPGVSAQSWSGLLTDQVKGAVLLSYGAGNAPDKDDALLAMLKNATERGVCIVNVSQCGAGSVVAGAYAAGSALVKAGVVSGQDMTYEAAFTKLHVAIGCGLEGAALRAEFE
>NC_015276.1|WP_013662853.1|4121756_4122653_-|DMT-family-transporter
MQIFFVLLVLIWSTGFITGKFIVGLVDPNIYLAIRFALTGLLFLIGALLFKRSFPSFSELPKHILAGILLNGLYLGFAYVAVANGLPAGVMALIGSLQPILVTLLAFLIMKEKTSATGLVGMAVAIFGLYLVIGPSLHVEDHSYGIAMVSLGILAIFCLSFGSVYQKMSISQSDIVTTMAIQNLAAAAVSCVFVFVLGERLLIVNATSLALFAWGILVLSCGGVFLLVWLYRKVQASLVSSLLLLVPPLAAIESYFIFGESMTWVQISGVVTTLAGVYMSRLNIKFGQAKKEPVQQSH
>NC_015276.1|WP_013662854.1|4122813_4124547_-|arginine--tRNA-ligase
MNIQTLLNQRIQAAMIAAGAPEESPALVRQSAKVQFGDYQANGIMGVAKKLKTNPRAFAEQVLEKLDLTDLADKVEIAGPGFINVFLKNAWLAQEQKSLRKSERLDVVTVSEPQTVVVDYSAPNLAKEMHVGHLRSTVIGDAVVRTLEFLGHKVVRQNHVGDWGTQFGMLLAYMERLRAESSEISMALSDLETFYREAKKCFDDDEAFSVRARELVVKLQSGDEECKALWQDFINISLEHCEETYQMLGVSLERKNVMPESAYNDDLQNVINDLDAKGLIKEDQGAKCVFLEEFANKDGEITPIIVQKTGGGFLYSTTDLAAVRYRQNVLKADRALYFVDARQSLHFEQIFTLSRKAGFADDSISLEHMPFGTVMGSDGKPFKTRSGGVAKLSALLEEAQERAYKLVASKNPDMAEDELRNIGRVVGVASVKYADLSKNRTSDYVFNWDTMLSFEGNTAPYLQYAYSRVASIVRNADIDAAALQGDISVIEDQERALAVKLVQFEEAIQQVGNDGMPHFLCAYLYELAGTFMSFYEACPILKADEEVKNSRLQLALNTASTLKLGLSLLGIETLERM
>NC_015276.1|WP_013662856.1|4125485_4125968_+|hypothetical-protein
MQEIHERVIVTNDLSCTRGNSEVAVVHACKSPCHQGAVGYRGKLPSTHPNYLVLEQEYDLFLNIIDPPIPLFMPPLFTEFLAFANKHWSQDRKLLIHCNQGESRAPSLAMLFLAKGVFAIPDTSYEVARLEFEKLYSRYNPGKGIETYFSKNWSQLGSNF
>NC_015276.1|WP_148231134.1|4126088_4126706_+|hypothetical-protein
MALTLIGLIPWAPKWLESVKFGDFEAKFRKIKEELDATKQEVSLLKHRYSELEDDYLNECKKFDPDASPQVLNKLATSLKGKAKGLSSVDFLFRDLNLNSPQHIAFGAACAMQVRPAFHALDAVTNLLSALAKKPDINGYRLKTIYRLLMAIDEVVRLNEKNQDVELVSKKQSESIKKMTVLVVDNPQCRNDDTAKLASKIAEKL
>NC_015276.1|WP_013662858.1|4126763_4127543_+|toll/interleukin-1-receptor-domain-containing-protein
MAFDIFISHASEDKEIVARPIASFLDENTELTVWYDEFTLNPGDSLSEKIDYGLANSRYGLVVISPAFMSKNWPKKELRGLNALNVEGQNKLIPVWHNVAKEEVISFSPTIADVYALNTANGVSSVCDEIIKVVVSVETSIDELIDKAQKLLKDGEFELSVMSASKALRQHLEFIALQRLGPKYFRKKGIKRFSLLQLLDALHSKGGIIPKDSESEIDRKKLNSLRNIAVHGSKKKELGFKNSNAFIVQVRIIIRESKI
>NC_015276.1|WP_013662859.1|4127626_4128406_+|hypothetical-protein
MDLVSKSGYSVANSLAKSFASNVIERWTRHRAEKFFIEFQNKLLANRLEGDVQVNVSEEIEEILSTDIGSEVVFDAYRRVSLSKSKDIGPRIIGILTAELCIENRTTNDFEELIFSVAETLNDSEMADSVSTIKHWLSLSKHGKCKGYLAGSAYIEDDELKYVLDHSVIEDISYMANSKEVNLSTDSLYEEFGSGVQKLKSLGVLTTRIQQSTFSYHEDSERHIDQDGTAQVTLKLVTFPLSYRRILSLIEQAYSDAEL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015276_6	6.51\|3646839\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646839-3646870	32	KY626177	Marinomonas phage CPG1g, complete genome	2023-2054	0	1.0
NC_015276_6	6.51\|3646839\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646839-3646870	32	MF481197	Marinomonas phage CB5A, complete genome	3094-3125	0	1.0
NC_015276_6	6.51\|3646839\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646839-3646870	32	NC_047821	Marinomonas phage CPP1m, complete genome	2024-2055	0	1.0
NC_015276_6	6.52\|3646899\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646899-3646930	32	KY626177	Marinomonas phage CPG1g, complete genome	8481-8512	1	0.969
NC_015276_6	6.52\|3646899\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646899-3646930	32	MF481197	Marinomonas phage CB5A, complete genome	9543-9574	1	0.969
NC_015276_6	6.52\|3646899\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646899-3646930	32	NC_047821	Marinomonas phage CPP1m, complete genome	8482-8513	1	0.969
NC_015276_2	2.78\|694794\|24\|NC_015276\|CRT	694794-694817	24	MN693975	Marine virus AFVG_250M1117, complete genome	46454-46477	3	0.875
NC_015276_6	6.50\|3646779\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646779-3646810	32	MF481197	Marinomonas phage CB5A, complete genome	5581-5612	3	0.906
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP045197	Acinetobacter indicus strain TQ23 plasmid p23TQ-NDM, complete sequence	36315-36340	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP034756	Enterobacter hormaechei subsp. hoffmannii strain Eh1 plasmid p2, complete sequence	89545-89570	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP044475	Acinetobacter schindleri strain HZE33-1 plasmid pHZE33-1-1, complete sequence	11088-11113	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP044446	Acinetobacter indicus strain CMG3-2 plasmid pCMG3-2-1, complete sequence	82463-82488	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP044484	Acinetobacter schindleri strain HZE30-1 plasmid pHZE30-1-1, complete sequence	27607-27632	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP045133	Acinetobacter indicus strain TQ18 plasmid p18TQ-NDM, complete sequence	10833-10858	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_KT965092	Acinetobacter towneri strain G165 plasmid pNDM-GJ01, complete sequence	24052-24077	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP045130	Acinetobacter indicus strain TQ04 plasmid p4TQ-NDM, complete sequence	35773-35798	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_023322	Acinetobacter bereziniae strain CHI-40-1 plasmid pNDM-40-1, complete sequence	17161-17186	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_KC887917	Enterobacter cloacae isolate ECL3 plasmid pECL3-NDM-1, complete sequence	19729-19754	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP044451	Acinetobacter indicus strain MMS9-2 plasmid pMMS9-2-1, complete sequence	83619-83644	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP010370	Acinetobacter nosocomialis strain 6411 plasmid p6411-9.012kb, complete sequence	26229-26254	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_018994	Escherichia coli plasmid pNDM-1_Dok01, complete sequence	131922-131947	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP020854	Klebsiella pneumoniae strain KPN528 plasmid pKPN528-1, complete sequence	64465-64490	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP032278	Acinetobacter sp. WCHAc010034 plasmid pNDM1_010034, complete sequence	38037-38062	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP026617	Acinetobacter sp. SWBY1 plasmid pSWBY1, complete sequence	11812-11837	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP012754	Klebsiella pneumoniae strain KP617 plasmid KP-p1, complete sequence	17569-17594	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_KM210086	Acinetobacter lwoffii strain JN49-1 plasmid pNDM-JN01, complete sequence	12680-12705	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP031736	Klebsiella pneumoniae subsp. pneumoniae strain Klebsiella pneumoniae plasmid pKPM502, complete sequence	73345-73370	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP027532	Acinetobacter baumannii strain AR_0088 plasmid unnamed2, complete sequence	24585-24610	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP026127	Acinetobacter baumannii strain ABNIH28 plasmid pNDM-0285, complete sequence	10914-10939	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_025000	Acinetobacter lwoffii strain Iz4b plasmid pNDM-Iz4b, complete sequence	18867-18892	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP010399	Acinetobacter baumannii strain 6200 plasmid p6200-47.274kb, complete sequence	9034-9059	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP035935	Acinetobacter cumulans strain WCHAc060092 plasmid pNDM1_060092, complete sequence	43550-43575	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_020818	Acinetobacter baumannii strain GF216 plasmid pNDM-AB, complete sequence	15161-15186	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP020068	Klebsiella pneumoniae strain AR_0068 plasmid unitig_1, complete sequence	244462-244487	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_KJ003839	Acinetobacter pittii strain Acinetobacter pitti plasmid pNDM-AP, complete sequence	27808-27833	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP028929	Klebsiella pneumoniae strain AR_0153 plasmid unnamed1, complete sequence	159539-159564	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP016921	Klebsiella pneumoniae isolate 11 plasmid pIncHI1B_DHQP1300920, complete sequence	43526-43551	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	CP050156	Klebsiella pneumoniae plasmid Carbapenemase(NDM-1)_IncH1B, complete sequence	222433-222458	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP022612	Klebsiella pneumoniae strain CDC 0106 plasmid unnamed1, complete sequence	147195-147220	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	AMXH01000087	Acinetobacter pittii strain XM1570 plasmid pXM1, complete sequence, whole genome shotgun sequence	18867-18892	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_JQ739157	Acinetobacter pittii strain ABCA95 plasmid pABCA95, complete sequence	5924-5949	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_AP018748	Klebsiella pneumoniae strain KP33 plasmid pKP3301, complete sequence	100773-100798	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_019985	Acinetobacter baumannii ZW85-1 plasmid pAbNDM-1, complete sequence	19961-19986	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP046043	Acinetobacter towneri strain 19110F47 plasmid p19110F47-1, complete sequence	29514-29539	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	LC483156	Acinetobacter pittii SU1805 plasmid pSU1805NDM DNA, complete sequence	28309-28334	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_017261	Buchnera aphidicola str. Ua (Uroleucon ambrosiae) plasmid pLeu, complete sequence	3735-3760	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP006799	Klebsiella pneumoniae subsp. pneumoniae PittNDM01 plasmid p1, complete sequence	17569-17594	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP015617	Acinetobacter schindleri strain ACE plasmid p2AsACE, complete sequence	36818-36843	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	MT002974	Acinetobacter baumannii strain AB17 plasmid pAB17, complete sequence	28383-28408	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP032142	Acinetobacter sp. WCHAc010052 plasmid pNDM1_010052, complete sequence	19093-19118	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_022589	Providencia rettgeri strain 09ACRGNY2001 plasmid pPrY2001, complete sequence	73289-73314	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP026425	Acinetobacter sp. ACNIH1 plasmid pNDM-9c17, complete sequence	22368-22393	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	CP046596	Acinetobacter indicus strain FS42-2 plasmid pFS42-2-1, complete sequence	34835-34860	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	LC537594	Acinetobacter lwoffii SU1904 plasmid pSU1904NDM DNA, complete sequence	30947-30972	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_019268	Acinetobacter lwoffii plasmid pNDM-BJ01, complete sequence	18867-18892	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_019281	Acinetobacter lwoffii plasmid pNDM-BJ02, complete sequence	17758-17783	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NC_025116	Acinetobacter sp. M131 plasmid pM131_NDM1, complete sequence	27465-27490	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_MK053934	Acinetobacter nosocomialis strain IEC38057 plasmid pIEC38057, complete sequence	28383-28408	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_AP018143	Escherichia coli strain M214 isolate M214 plasmid pM214_AC2, complete sequence	143026-143051	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP045128	Acinetobacter indicus strain XG03 plasmid pXG03-X3, complete sequence	26492-26517	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_KM210088	Acinetobacter sp. JN247 plasmid pNDM-JN02, complete sequence	12680-12705	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP041229	Acinetobacter haemolyticus strain AN54 plasmid pAhaeAN54e, complete sequence	35692-35717	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP032132	Acinetobacter chinensis strain WCHAc010005 plasmid pNDM1_010005, complete sequence	30692-30717	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP044464	Acinetobacter schindleri strain HZE23-1 plasmid pHZE23-1-1, complete sequence	89877-89902	5	0.808
NC_015276_2	2.11\|694724\|26\|NC_015276\|CRISPRCasFinder	694724-694749	26	NZ_CP034406	Klebsiella pneumoniae strain NH34 plasmid pNH34.1, complete sequence	259776-259801	5	0.808
NC_015276_6	6.40\|3646179\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646179-3646210	32	MN582060	Podoviridae sp. ctg2L5, complete genome	36180-36211	5	0.844
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	AP019525	Tenacibaculum phage PTm5 DNA, complete genome	192302-192333	6	0.812
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	AP019524	Tenacibaculum phage PTm1 DNA, complete genome	191241-191272	6	0.812
NC_015276_2	2.52\|697628\|36\|NC_015276\|CRISPRCasFinder,CRT	697628-697663	36	CP048748	Buchnera aphidicola (Microlophium carnosum) isolate MCAR-56B plasmid pLeu, complete sequence	6912-6947	7	0.806
NC_015276_6	6.1\|3643838\|31\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3643838-3643868	31	NZ_CP045339	Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence	51068-51098	7	0.774
NC_015276_6	6.33\|3645759\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645759-3645790	32	NZ_CP029096	Pseudomonas aeruginosa strain AR439 plasmid unnamed2, complete sequence	271116-271147	7	0.781
NC_015276_6	6.47\|3646599\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646599-3646630	32	MK448861	Streptococcus phage Javan174, complete genome	33458-33489	7	0.781
NC_015276_2	2.7\|694444\|34\|NC_015276\|CRISPRCasFinder,PILER-CR,CRT	694444-694477	34	MT446411	UNVERIFIED: Escherichia virus TH40, complete genome	39298-39331	8	0.765
NC_015276_2	2.7\|694444\|34\|NC_015276\|CRISPRCasFinder,PILER-CR,CRT	694444-694477	34	MT446415	UNVERIFIED: Escherichia virus TH44, complete genome	118998-119031	8	0.765
NC_015276_2	2.12\|694785\|33\|NC_015276\|CRISPRCasFinder	694785-694817	33	MN694803	Marine virus AFVG_250M814, complete genome	11850-11882	8	0.758
NC_015276_2	2.62\|694724\|32\|NC_015276\|PILER-CR	694724-694755	32	AY082070	Bacteriophage phi3626, complete genome	15623-15654	8	0.75
NC_015276_2	2.62\|694724\|32\|NC_015276\|PILER-CR	694724-694755	32	NC_003524	Clostridium phage phi3626, complete genome	15623-15654	8	0.75
NC_015276_2	2.63\|694791\|33\|NC_015276\|PILER-CR	694791-694823	33	MN694803	Marine virus AFVG_250M814, complete genome	11850-11882	8	0.758
NC_015276_3	3.4\|710595\|34\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	710595-710628	34	NZ_AP014825	Geminocystis sp. NIES-3709 plasmid pGM3709_04, complete sequence	31360-31393	8	0.765
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP032297	Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence	214108-214140	8	0.758
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP036488	Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence	351243-351275	8	0.758
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NC_017060	Rahnella aquatilis HX2 plasmid PRA1, complete sequence	439314-439346	8	0.758
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP034838	Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence	424336-424368	8	0.758
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP034838	Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence	426958-426990	8	0.758
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP034839	Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence	424336-424368	8	0.758
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP034839	Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence	426958-426990	8	0.758
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP034837	Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence	380843-380875	8	0.758
NC_015276_6	6.2\|3643897\|33\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3643897-3643929	33	NZ_CP030360	Salinibacter ruber strain SP38 plasmid pSR76, complete sequence	5431-5463	8	0.758
NC_015276_6	6.6\|3644137\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644137-3644168	32	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	202786-202817	8	0.75
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	CP047390	Agrobacterium sp. CGMCC 11546 plasmid pB	232394-232425	8	0.75
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NC_003064	Agrobacterium fabrum str. C58 plasmid At, complete sequence	269598-269629	8	0.75
NC_015276_6	6.25\|3645279\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645279-3645310	32	NZ_CP039041	Piscirickettsia salmonis strain Psal-072 plasmid unnamed1, complete sequence	96895-96926	8	0.75
NC_015276_6	6.28\|3645459\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645459-3645490	32	NC_014534	Gloeothece verrucosa PCC 7822 plasmid Cy782202, complete sequence	5268-5299	8	0.75
NC_015276_6	6.34\|3645819\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645819-3645850	32	NZ_CP013105	Paraburkholderia caribensis strain MWAP64 plasmid 2, complete sequence	331812-331843	8	0.75
NC_015276_6	6.39\|3646119\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646119-3646150	32	NZ_CP040850	Enterococcus faecium strain F17E0263 plasmid p_unnamned1, complete sequence	94042-94073	8	0.75
NC_015276_6	6.41\|3646239\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646239-3646270	32	MT811961	Vibrio phage vB_pir03, complete genome	191425-191456	8	0.75
NC_015276_6	6.47\|3646599\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646599-3646630	32	NZ_AP014823	Geminocystis sp. NIES-3709 plasmid pGM3709_02, complete sequence	16285-16316	8	0.75
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	KC465899	Pelagibacter phage HTVC008M, complete genome	56750-56781	8	0.75
NC_015276_6	6.51\|3646839\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646839-3646870	32	NC_011738	Gloeothece citriformis PCC 7424 plasmid pP742401, complete sequence	213203-213234	8	0.75
NC_015276_7	7.36\|3898549\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3898549-3898580	32	NZ_CP016745	Lactococcus lactis subsp. cremoris strain JM2 plasmid pMPJM2, complete sequence	72913-72944	8	0.75
NC_015276_7	7.36\|3898549\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3898549-3898580	32	NZ_CP016746	Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence	181109-181140	8	0.75
NC_015276_2	2.31\|696138\|36\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	696138-696173	36	MN855673	Bacteriophage sp. isolate 200, complete genome	2017-2052	9	0.75
NC_015276_2	2.59\|693983\|32\|NC_015276\|PILER-CR	693983-694014	32	NC_031077	Enterobacter phage Tyrion, complete genome	20368-20399	9	0.719
NC_015276_2	2.62\|694724\|32\|NC_015276\|PILER-CR	694724-694755	32	NC_021529	Vibrio phage nt-1, complete genome	17446-17477	9	0.719
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP032297	Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence	211485-211517	9	0.727
NC_015276_5	5.1\|2572980\|33\|NC_015276\|CRISPRCasFinder	2572980-2573012	33	NZ_CP034837	Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence	383466-383498	9	0.727
NC_015276_6	6.3\|3643958\|31\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3643958-3643988	31	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	739749-739779	9	0.71
NC_015276_6	6.6\|3644137\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644137-3644168	32	NC_016585	Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence	1006964-1006995	9	0.719
NC_015276_6	6.17\|3644799\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644799-3644830	32	NZ_KY503037	Pseudomonas fluorescens strain PC24 plasmid pPHE24, complete sequence	26672-26703	9	0.719
NC_015276_6	6.17\|3644799\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644799-3644830	32	NC_014124	Pseudomonas putida plasmid pDK1, complete sequence	5768-5799	9	0.719
NC_015276_6	6.17\|3644799\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644799-3644830	32	NC_008275	Pseudomonas putida MT53 plasmid pWW53, complete sequence	5844-5875	9	0.719
NC_015276_6	6.29\|3645519\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645519-3645550	32	CP047036	Rhodobacter sphaeroides strain DSM 158 plasmid pDx, complete sequence	2950-2981	9	0.719
NC_015276_6	6.30\|3645579\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645579-3645610	32	MG592488	Vibrio phage 1.115.A._10N.222.49.B11, partial genome	31394-31425	9	0.719
NC_015276_6	6.30\|3645579\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645579-3645610	32	MG592489	Vibrio phage 1.115.B._10N.222.49.B11, partial genome	31393-31424	9	0.719
NC_015276_6	6.34\|3645819\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645819-3645850	32	MN694202	Marine virus AFVG_250M1202, complete genome	11685-11716	9	0.719
NC_015276_6	6.47\|3646599\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646599-3646630	32	MK893987	Staphylococcus phage PMBT8, complete genome	59200-59231	9	0.719
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	NZ_LR135205	Enterococcus faecium isolate E7171 plasmid 3	19439-19470	9	0.719
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	NC_011774	Bacillus cereus G9842 plasmid pG9842_140, complete sequence	4207-4238	9	0.719
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	NZ_CP008815	Enterococcus faecalis ATCC 29212 plasmid 1, complete sequence	1751-1782	9	0.719
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	MF498774	Aeromonas phage AS-yj, partial genome	99752-99783	9	0.719
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	MH791398	UNVERIFIED: Aeromonas phage Asswx_1, complete genome	47344-47375	9	0.719
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	MN871442	UNVERIFIED: Aeromonas phage Aszh-1, complete genome	209422-209453	9	0.719
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	MN871441	UNVERIFIED: Aeromonas phage AsSzw2, complete genome	114421-114452	9	0.719
NC_015276_7	7.1\|3896449\|32\|NC_015276\|CRISPRCasFinder,CRT	3896449-3896480	32	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	475643-475674	9	0.719
NC_015276_7	7.7\|3896809\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3896809-3896840	32	MN693605	Marine virus AFVG_25M414, complete genome	17383-17414	9	0.719
NC_015276_7	7.10\|3896989\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3896989-3897020	32	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	34334-34365	9	0.719
NC_015276_7	7.10\|3896989\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3896989-3897020	32	MT080596	UNVERIFIED: Staphylococcus phage vB_SauM_EW42, complete genome	124683-124714	9	0.719
NC_015276_7	7.10\|3896989\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3896989-3897020	32	MT080593	UNVERIFIED: Staphylococcus phage vB_SauM_EW36, complete genome	60745-60776	9	0.719
NC_015276_7	7.11\|3897049\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897049-3897080	32	AP013512	Uncultured Mediterranean phage uvMED DNA, complete genome, group G21, isolate: uvMED-CGR-C84-MedDCM-OCT-S29-C65	21027-21058	9	0.719
NC_015276_7	7.11\|3897049\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897049-3897080	32	MN693620	Marine virus AFVG_250M617, complete genome	2719-2750	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP028227	Lactobacillus plantarum strain SRCM101187 plasmid unnamed1, complete sequence	40417-40448	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP025691	Lactobacillus plantarum strain IRG1 plasmid pIRG101, complete sequence	19844-19875	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP021502	Lactobacillus plantarum strain SRCM102022 plasmid pPL2022-1, complete sequence	7147-7178	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP021475	Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-4, complete sequence	61918-61949	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP016271	Lactobacillus plantarum subsp. plantarum strain CGMCC 1.557 plasmid pLp1, complete sequence	16313-16344	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP024060	Lactobacillus plantarum strain KACC 92189 plasmid unnamed2	38637-38668	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP032360	Lactobacillus plantarum strain ZFM55 plasmid unnamed1, complete sequence	41838-41869	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP023303	Lactobacillus plantarum strain pc-26 plasmid p.pc-2602, complete sequence	4775-4806	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP032643	Lactobacillus plantarum strain ZFM9 plasmid unnamed1, complete sequence	7353-7384	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP035146	Lactobacillus plantarum strain SRCM103357 plasmid unnamed3	9374-9405	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP035146	Lactobacillus plantarum strain SRCM103357 plasmid unnamed3	69830-69861	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP028262	Lactobacillus plantarum strain SRCM102737 plasmid unnamed1, complete sequence	14854-14885	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP048024	Lactobacillus plantarum strain CACC 558 plasmid p2CACC558, complete sequence	43833-43864	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP028223	Lactobacillus plantarum strain SRCM101105 plasmid unnamed1, complete sequence	5087-5118	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP028276	Lactobacillus plantarum strain SRCM100995 plasmid unnamed1, complete sequence	55570-55601	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP028244	Lactobacillus plantarum strain SRCM101518 plasmid unnamed3, complete sequence	6191-6222	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	NZ_CP054261	Lactobacillus plantarum strain TCI507 plasmid unnamed2	29620-29651	9	0.719
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	MK368614	Vibrio phage 2 TSL-2019, complete genome	67798-67829	9	0.719
NC_015276_7	7.29\|3898129\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3898129-3898160	32	NC_018069	Solibacillus silvestris StLB046 plasmid pSSIL1, complete sequence	1637-1668	9	0.719
NC_015276_7	7.31\|3898249\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3898249-3898280	32	MN047793	Xanthomonas phage Xoo-sp13, complete genome	270978-271009	9	0.719
NC_015276_7	7.36\|3898549\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3898549-3898580	32	CP016196	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence	48592-48623	9	0.719
NC_015276_2	2.41\|696846\|35\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	696846-696880	35	AP014136	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C47-MedDCM-OCT-S34-C10, * SEQUENCING IN PROGRESS *	10461-10495	10	0.714
NC_015276_2	2.41\|696846\|35\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	696846-696880	35	AP014135	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C47-MedDCM-OCT-S32-C28, * SEQUENCING IN PROGRESS *	6703-6737	10	0.714
NC_015276_2	2.41\|696846\|35\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	696846-696880	35	NZ_CP012203	Alteromonas macleodii strain HOT1A3 plasmid pAM1A3, complete sequence	13676-13710	10	0.714
NC_015276_2	2.41\|696846\|35\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	696846-696880	35	NZ_CP039853	Salinimonas sp. KX18D6 plasmid plas12, complete sequence	337716-337750	10	0.714
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1898813-1898844	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	616355-616386	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1898846-1898877	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1898811-1898842	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	618771-618802	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	618776-618807	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1480125-1480156	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1449118-1449149	10	0.688
NC_015276_6	6.9\|3644317\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3644317-3644348	32	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1449118-1449149	10	0.688
NC_015276_6	6.39\|3646119\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646119-3646150	32	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	858454-858485	10	0.688
NC_015276_6	6.47\|3646599\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646599-3646630	32	AB711120	Bacillus phage PM1 DNA, complete genome	4901-4932	10	0.688
NC_015276_6	6.49\|3646719\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3646719-3646750	32	NC_029073	Geobacillus virus E3, complete genome	69879-69910	10	0.688
NC_015276_7	7.9\|3896929\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3896929-3896960	32	NC_017472	Lactobacillus amylovorus GRL1118 plasmid p2, complete sequence	41118-41149	10	0.688
NC_015276_7	7.21\|3897649\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897649-3897680	32	MN562221	Photobacterium phage PDCC-1, complete genome	170829-170860	10	0.688
NC_015276_6	6.24\|3645219\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645219-3645250	32	NC_014838	Pantoea sp. At-9b plasmid pPAT9B01, complete sequence	79212-79243	11	0.656
NC_015276_6	6.29\|3645519\|32\|NC_015276\|PILER-CR,CRISPRCasFinder,CRT	3645519-3645550	32	MH067977	Arthrobacter sp. strain ANT_H8 plasmid pA8H1, complete sequence	1391-1422	11	0.656
NC_015276_7	7.23\|3897769\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897769-3897800	32	NZ_CP051294	Mesorhizobium sp. NZP2077 plasmid pMSNZP2077A, complete sequence	24147-24178	11	0.656
NC_015276_7	7.23\|3897769\|32\|NC_015276\|CRISPRCasFinder,CRT,PILER-CR	3897769-3897800	32	NZ_CP033363	Mesorhizobium sp. NZP2077 plasmid pMSNZP2077NSa, complete sequence	24147-24178	11	0.656

1. spacer 6.51|3646839|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to KY626177 (Marinomonas phage CPG1g, complete genome) position: , mismatch: 0, identity: 1.0

cgtactaagcgtatgctaagaaacaacttaaa	CRISPR spacer
cgtactaagcgtatgctaagaaacaacttaaa	Protospacer
********************************

2. spacer 6.51|3646839|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MF481197 (Marinomonas phage CB5A, complete genome) position: , mismatch: 0, identity: 1.0

cgtactaagcgtatgctaagaaacaacttaaa	CRISPR spacer
cgtactaagcgtatgctaagaaacaacttaaa	Protospacer
********************************

3. spacer 6.51|3646839|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_047821 (Marinomonas phage CPP1m, complete genome) position: , mismatch: 0, identity: 1.0

cgtactaagcgtatgctaagaaacaacttaaa	CRISPR spacer
cgtactaagcgtatgctaagaaacaacttaaa	Protospacer
********************************

4. spacer 6.52|3646899|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to KY626177 (Marinomonas phage CPG1g, complete genome) position: , mismatch: 1, identity: 0.969

ttatgctttgctgtgaatggattcatggatgc	CRISPR spacer
ttatgctttgctgtgaatggattcattgatgc	Protospacer
************************** *****

5. spacer 6.52|3646899|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MF481197 (Marinomonas phage CB5A, complete genome) position: , mismatch: 1, identity: 0.969

ttatgctttgctgtgaatggattcatggatgc	CRISPR spacer
ttatgctttgctgtgaatggattcattgatgc	Protospacer
************************** *****

6. spacer 6.52|3646899|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_047821 (Marinomonas phage CPP1m, complete genome) position: , mismatch: 1, identity: 0.969

ttatgctttgctgtgaatggattcatggatgc	CRISPR spacer
ttatgctttgctgtgaatggattcattgatgc	Protospacer
************************** *****

7. spacer 2.78|694794|24|NC_015276|CRT matches to MN693975 (Marine virus AFVG_250M1117, complete genome) position: , mismatch: 3, identity: 0.875

tagaagatatcaagaagctagaga	CRISPR spacer
tggaagatatcaagaagctaggta	Protospacer
*.*******************. *

8. spacer 6.50|3646779|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MF481197 (Marinomonas phage CB5A, complete genome) position: , mismatch: 3, identity: 0.906

attagcagaatcgaagcacatcccgtacatta	CRISPR spacer
attagcagcatcgaagcacataccgtacatga	Protospacer
******** ************ ******** *

9. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP045197 (Acinetobacter indicus strain TQ23 plasmid p23TQ-NDM, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

10. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP034756 (Enterobacter hormaechei subsp. hoffmannii strain Eh1 plasmid p2, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

11. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP044475 (Acinetobacter schindleri strain HZE33-1 plasmid pHZE33-1-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

12. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP044446 (Acinetobacter indicus strain CMG3-2 plasmid pCMG3-2-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

13. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP044484 (Acinetobacter schindleri strain HZE30-1 plasmid pHZE30-1-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

14. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP045133 (Acinetobacter indicus strain TQ18 plasmid p18TQ-NDM, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

15. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_KT965092 (Acinetobacter towneri strain G165 plasmid pNDM-GJ01, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

16. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP045130 (Acinetobacter indicus strain TQ04 plasmid p4TQ-NDM, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

17. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_023322 (Acinetobacter bereziniae strain CHI-40-1 plasmid pNDM-40-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

18. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_KC887917 (Enterobacter cloacae isolate ECL3 plasmid pECL3-NDM-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

19. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP044451 (Acinetobacter indicus strain MMS9-2 plasmid pMMS9-2-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

20. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP010370 (Acinetobacter nosocomialis strain 6411 plasmid p6411-9.012kb, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

21. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_018994 (Escherichia coli plasmid pNDM-1_Dok01, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

22. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP020854 (Klebsiella pneumoniae strain KPN528 plasmid pKPN528-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

23. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP032278 (Acinetobacter sp. WCHAc010034 plasmid pNDM1_010034, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

24. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP026617 (Acinetobacter sp. SWBY1 plasmid pSWBY1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

25. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP012754 (Klebsiella pneumoniae strain KP617 plasmid KP-p1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

26. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_KM210086 (Acinetobacter lwoffii strain JN49-1 plasmid pNDM-JN01, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

27. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP031736 (Klebsiella pneumoniae subsp. pneumoniae strain Klebsiella pneumoniae plasmid pKPM502, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

28. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP027532 (Acinetobacter baumannii strain AR_0088 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

29. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP026127 (Acinetobacter baumannii strain ABNIH28 plasmid pNDM-0285, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

30. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_025000 (Acinetobacter lwoffii strain Iz4b plasmid pNDM-Iz4b, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

31. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP010399 (Acinetobacter baumannii strain 6200 plasmid p6200-47.274kb, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

32. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP035935 (Acinetobacter cumulans strain WCHAc060092 plasmid pNDM1_060092, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

33. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_020818 (Acinetobacter baumannii strain GF216 plasmid pNDM-AB, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

34. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP020068 (Klebsiella pneumoniae strain AR_0068 plasmid unitig_1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

35. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_KJ003839 (Acinetobacter pittii strain Acinetobacter pitti plasmid pNDM-AP, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

36. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP028929 (Klebsiella pneumoniae strain AR_0153 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

37. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP016921 (Klebsiella pneumoniae isolate 11 plasmid pIncHI1B_DHQP1300920, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

38. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to CP050156 (Klebsiella pneumoniae plasmid Carbapenemase(NDM-1)_IncH1B, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

39. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP022612 (Klebsiella pneumoniae strain CDC 0106 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

40. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to AMXH01000087 (Acinetobacter pittii strain XM1570 plasmid pXM1, complete sequence, whole genome shotgun sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

41. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_JQ739157 (Acinetobacter pittii strain ABCA95 plasmid pABCA95, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

42. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_AP018748 (Klebsiella pneumoniae strain KP33 plasmid pKP3301, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

43. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_019985 (Acinetobacter baumannii ZW85-1 plasmid pAbNDM-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

44. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP046043 (Acinetobacter towneri strain 19110F47 plasmid p19110F47-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

45. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to LC483156 (Acinetobacter pittii SU1805 plasmid pSU1805NDM DNA, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

46. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_017261 (Buchnera aphidicola str. Ua (Uroleucon ambrosiae) plasmid pLeu, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
ttgactagttcgataaatttctttat	Protospacer
 **** ****************  *

47. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP006799 (Klebsiella pneumoniae subsp. pneumoniae PittNDM01 plasmid p1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

48. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP015617 (Acinetobacter schindleri strain ACE plasmid p2AsACE, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

49. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to MT002974 (Acinetobacter baumannii strain AB17 plasmid pAB17, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

50. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP032142 (Acinetobacter sp. WCHAc010052 plasmid pNDM1_010052, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

51. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_022589 (Providencia rettgeri strain 09ACRGNY2001 plasmid pPrY2001, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

52. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP026425 (Acinetobacter sp. ACNIH1 plasmid pNDM-9c17, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

53. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to CP046596 (Acinetobacter indicus strain FS42-2 plasmid pFS42-2-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

54. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to LC537594 (Acinetobacter lwoffii SU1904 plasmid pSU1904NDM DNA, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

55. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_019268 (Acinetobacter lwoffii plasmid pNDM-BJ01, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

56. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_019281 (Acinetobacter lwoffii plasmid pNDM-BJ02, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

57. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NC_025116 (Acinetobacter sp. M131 plasmid pM131_NDM1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

58. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_MK053934 (Acinetobacter nosocomialis strain IEC38057 plasmid pIEC38057, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

59. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_AP018143 (Escherichia coli strain M214 isolate M214 plasmid pM214_AC2, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

60. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP045128 (Acinetobacter indicus strain XG03 plasmid pXG03-X3, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

61. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_KM210088 (Acinetobacter sp. JN247 plasmid pNDM-JN02, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

62. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP041229 (Acinetobacter haemolyticus strain AN54 plasmid pAhaeAN54e, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

63. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP032132 (Acinetobacter chinensis strain WCHAc010005 plasmid pNDM1_010005, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

64. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP044464 (Acinetobacter schindleri strain HZE23-1 plasmid pHZE23-1-1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

65. spacer 2.11|694724|26|NC_015276|CRISPRCasFinder matches to NZ_CP034406 (Klebsiella pneumoniae strain NH34 plasmid pNH34.1, complete sequence) position: , mismatch: 5, identity: 0.808

atgacaagttcgataaatttctagaa	CRISPR spacer
atgacaagttcgataagtttcaactc	Protospacer
****************.**** *

66. spacer 6.40|3646179|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MN582060 (Podoviridae sp. ctg2L5, complete genome) position: , mismatch: 5, identity: 0.844

caaacatacacttatgaaccagatgatgatga	CRISPR spacer
caaacatacacttctgaaccagaagatattgt	Protospacer
************* ********* ***. **

67. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to AP019525 (Tenacibaculum phage PTm5 DNA, complete genome) position: , mismatch: 6, identity: 0.812

-acactagggaaaaagtagaagcacattattta	CRISPR spacer
gatatta-gcaaaaggtagaagtacattattta	Protospacer
 *.*.** * ****.*******.**********

68. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to AP019524 (Tenacibaculum phage PTm1 DNA, complete genome) position: , mismatch: 6, identity: 0.812

-acactagggaaaaagtagaagcacattattta	CRISPR spacer
gatatta-gcaaaaggtagaagtacattattta	Protospacer
 *.*.** * ****.*******.**********

69. spacer 2.52|697628|36|NC_015276|CRISPRCasFinder,CRT matches to CP048748 (Buchnera aphidicola (Microlophium carnosum) isolate MCAR-56B plasmid pLeu, complete sequence) position: , mismatch: 7, identity: 0.806

ttctctgtttatttttttaataaaaagtactctttc	CRISPR spacer
ctctctttttatttttttaataaaaaatacttataa	Protospacer
.***** *******************.****. *

70. spacer 6.1|3643838|31|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045339 (Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence) position: , mismatch: 7, identity: 0.774

-gcgaggcttaggcataaaaaaccgctgatgc	CRISPR spacer
cgtgaaattt-ggcataaaaaagcgctgatga	Protospacer
 *.**...** *********** ********

71. spacer 6.33|3645759|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029096 (Pseudomonas aeruginosa strain AR439 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

aacagtggaaacaggaaccccaatggctctaa---	CRISPR spacer
aacagtggcaagaggaaccccaat---ttgaagta	Protospacer
******** ** ************   *. **

72. spacer 6.47|3646599|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MK448861 (Streptococcus phage Javan174, complete genome) position: , mismatch: 7, identity: 0.781

gacaatttatctataaaagagattgacaagaa	CRISPR spacer
gagtttatctctataaaacagattggcaagaa	Protospacer
**   * * ********* ******.******

73. spacer 2.7|694444|34|NC_015276|CRISPRCasFinder,PILER-CR,CRT matches to MT446411 (UNVERIFIED: Escherichia virus TH40, complete genome) position: , mismatch: 8, identity: 0.765

agaagctaaggctaagacggctgagactaagaat	CRISPR spacer
cgaagctaaggctaagaaagctgagcatgagtac	Protospacer
 **************** .******  *.** *.

74. spacer 2.7|694444|34|NC_015276|CRISPRCasFinder,PILER-CR,CRT matches to MT446415 (UNVERIFIED: Escherichia virus TH44, complete genome) position: , mismatch: 8, identity: 0.765

agaagctaaggctaagacggctgagactaagaat	CRISPR spacer
tgaagctaaggctaagaaagctgagcatgagtac	Protospacer
 **************** .******  *.** *.

75. spacer 2.12|694785|33|NC_015276|CRISPRCasFinder matches to MN694803 (Marine virus AFVG_250M814, complete genome) position: , mismatch: 8, identity: 0.758

ctaacacactagaagatatcaagaagctagaga	CRISPR spacer
ccaacacgccagaagatatcaagaagttgagaa	Protospacer
*.*****.*.****************.*....*

76. spacer 2.62|694724|32|NC_015276|PILER-CR matches to AY082070 (Bacteriophage phi3626, complete genome) position: , mismatch: 8, identity: 0.75

atgacaagttcgataaatttctagaagatagc	CRISPR spacer
aagctattttcgataagtttgtagaagatagt	Protospacer
* * .*  ********.*** **********.

77. spacer 2.62|694724|32|NC_015276|PILER-CR matches to NC_003524 (Clostridium phage phi3626, complete genome) position: , mismatch: 8, identity: 0.75

atgacaagttcgataaatttctagaagatagc	CRISPR spacer
aagctattttcgataagtttgtagaagatagt	Protospacer
* * .*  ********.*** **********.

78. spacer 2.63|694791|33|NC_015276|PILER-CR matches to MN694803 (Marine virus AFVG_250M814, complete genome) position: , mismatch: 8, identity: 0.758

ctaacacactagaagatatcaagaagctagaga	CRISPR spacer
ccaacacgccagaagatatcaagaagttgagaa	Protospacer
*.*****.*.****************.*....*

79. spacer 3.4|710595|34|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014825 (Geminocystis sp. NIES-3709 plasmid pGM3709_04, complete sequence) position: , mismatch: 8, identity: 0.765

agcttgatgaggagatgatggcaataccgccaaa	CRISPR spacer
cacgggagaaggagatgatggcattaccgcaaaa	Protospacer
 .*  ** .************** ****** ***

80. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP032297 (Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcaggg	Protospacer
.**.********************** .  ..*

81. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP036488 (Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcaggg	Protospacer
.**.********************** .  ..*

82. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NC_017060 (Rahnella aquatilis HX2 plasmid PRA1, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcaggg	Protospacer
.**.********************** .  ..*

83. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP034838 (Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcaggg	Protospacer
.**.********************** .  ..*

84. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP034838 (Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcatgg	Protospacer
.**.********************** .   .*

85. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP034839 (Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcaggg	Protospacer
.**.********************** .  ..*

86. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP034839 (Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcatgg	Protospacer
.**.********************** .   .*

87. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP034837 (Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence) position: , mismatch: 8, identity: 0.758

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccaacctcccccttcgcaggg	Protospacer
.**.********************** .  ..*

88. spacer 6.2|3643897|33|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030360 (Salinibacter ruber strain SP38 plasmid pSR76, complete sequence) position: , mismatch: 8, identity: 0.758

ataaaagcagagtacgaaaacgccagaagtcga	CRISPR spacer
ttaaaagcaaagtacgcaaacgccatgaggctc	Protospacer
 ********.****** ******** .** *

89. spacer 6.6|3644137|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ctctcgcttgcgaggcggcgggagcatggcgc	CRISPR spacer
cgtgcgctggcgaggcggcgcgagcatggtag	Protospacer
* . **** *********** ********..

90. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to CP047390 (Agrobacterium sp. CGMCC 11546 plasmid pB) position: , mismatch: 8, identity: 0.75

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ttgctcgccatccccttcttcaccttcatggg	Protospacer
* *.**.********* *********** ..

91. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_003064 (Agrobacterium fabrum str. C58 plasmid At, complete sequence) position: , mismatch: 8, identity: 0.75

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ttgctcgccatccccttcttcaccttcatggg	Protospacer
* *.**.********* *********** ..

92. spacer 6.25|3645279|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039041 (Piscirickettsia salmonis strain Psal-072 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gaagatataagggcaagctttggtagtgttgc----	CRISPR spacer
aaagatataagcgcaggctttggt----ttgtacag	Protospacer
.********** ***.********    ***.

93. spacer 6.28|3645459|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_014534 (Gloeothece verrucosa PCC 7822 plasmid Cy782202, complete sequence) position: , mismatch: 8, identity: 0.75

caaggggaacaaatgaatcaaacgattaacaa	CRISPR spacer
cagatagaacaaatcaatcaaaccattaaaca	Protospacer
**.. .******** ******** *****  *

94. spacer 6.34|3645819|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013105 (Paraburkholderia caribensis strain MWAP64 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.75

ctcttgcttgctatttttcatagtctcgctaa	CRISPR spacer
cagttgcttgctatttcccatagtctgccaag	Protospacer
*  *************..********  * *.

95. spacer 6.39|3646119|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040850 (Enterococcus faecium strain F17E0263 plasmid p_unnamned1, complete sequence) position: , mismatch: 8, identity: 0.75

cccagcaaaaacgcttcattcgctttttgttg	CRISPR spacer
cgcccaatgaacacttgattcgctttttgttg	Protospacer
* *   * .***.*** ***************

96. spacer 6.41|3646239|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MT811961 (Vibrio phage vB_pir03, complete genome) position: , mismatch: 8, identity: 0.75

attttggcctgtattgctgtttcaatgtcggg	CRISPR spacer
aggttggcctttattgctgcttcaataaaagg	Protospacer
*  ******* ********.******.  .**

97. spacer 6.47|3646599|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014823 (Geminocystis sp. NIES-3709 plasmid pGM3709_02, complete sequence) position: , mismatch: 8, identity: 0.75

gacaatttatctataaaagagattgacaagaa	CRISPR spacer
tctaatttatctataaaagatagtgatataaa	Protospacer
  .***************** * ***.* .**

98. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to KC465899 (Pelagibacter phage HTVC008M, complete genome) position: , mismatch: 8, identity: 0.75

acactagggaaaaagtagaagcacattattta	CRISPR spacer
tctatgttcaaaaagtagaagaacattattta	Protospacer
 *  *.   ************ **********

99. spacer 6.51|3646839|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_011738 (Gloeothece citriformis PCC 7424 plasmid pP742401, complete sequence) position: , mismatch: 8, identity: 0.75

cgtactaagcgtatgctaagaaacaacttaaa	CRISPR spacer
cctgttgcgcgtattctaagaaataacttaag	Protospacer
* *..*. ****** ********.*******.

100. spacer 7.36|3898549|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016745 (Lactococcus lactis subsp. cremoris strain JM2 plasmid pMPJM2, complete sequence) position: , mismatch: 8, identity: 0.75

tgcgtcgggcatgttttttatcaattcgtaaa	CRISPR spacer
atcgtcaggcatgtttttaatcaatggatgaa	Protospacer
  ****.*********** ******  .*.**

101. spacer 7.36|3898549|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016746 (Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence) position: , mismatch: 8, identity: 0.75

tgcgtcgggcatgttttttatcaattcgtaaa	CRISPR spacer
atcgtcaggcatgtttttaatcaatggatgaa	Protospacer
  ****.*********** ******  .*.**

102. spacer 2.31|696138|36|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MN855673 (Bacteriophage sp. isolate 200, complete genome) position: , mismatch: 9, identity: 0.75

aataaacagcaaaagcaaaataaatcaattaacaaa	CRISPR spacer
cattgagttaaaaagcaaaataaaacaattaaaaaa	Protospacer
 ** .*    ************** ******* ***

103. spacer 2.59|693983|32|NC_015276|PILER-CR matches to NC_031077 (Enterobacter phage Tyrion, complete genome) position: , mismatch: 9, identity: 0.719

taaaatagtgtgacacgtcacaaa-----ctggagag	CRISPR spacer
aaaaatagcgtgacatgtcacaaaggccgctt-----	Protospacer
 *******.******.********     **

104. spacer 2.62|694724|32|NC_015276|PILER-CR matches to NC_021529 (Vibrio phage nt-1, complete genome) position: , mismatch: 9, identity: 0.719

atgacaagttcgataaatttctagaagatagc	CRISPR spacer
tcaatgagttcgaaaactttctagaagatgac	Protospacer
 ..*..******* ** ************..*

105. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP032297 (Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence) position: , mismatch: 9, identity: 0.727

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccagcctcccccttcgcaggg	Protospacer
.**.***********.********** .  ..*

106. spacer 5.1|2572980|33|NC_015276|CRISPRCasFinder matches to NZ_CP034837 (Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence) position: , mismatch: 9, identity: 0.727

caagaccccctcccaacctcccccttaaacaag	CRISPR spacer
taaaaccccctcccagcctcccccttcgcaggg	Protospacer
.**.***********.********** .  ..*

107. spacer 6.3|3643958|31|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 9, identity: 0.71

gggcagattactgcatacatcgaacagcttc	CRISPR spacer
aggcagattgctgcatacatcgatcgagagg	Protospacer
.********.************* *..

108. spacer 6.6|3644137|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_016585 (Azospirillum lipoferum 4B plasmid AZO_p1, complete sequence) position: , mismatch: 9, identity: 0.719

ctctcgcttgcgaggcggcgggagcatggcgc	CRISPR spacer
ggcgcccttggaaggcggcgggagcatggaag	Protospacer
  * * **** .***************** .

109. spacer 6.17|3644799|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY503037 (Pseudomonas fluorescens strain PC24 plasmid pPHE24, complete sequence) position: , mismatch: 9, identity: 0.719

atgctagctcactttccttatgtagacacata	CRISPR spacer
cagccagctcactttccttctgtaggaaggga	Protospacer
  **.************** *****. * . *

110. spacer 6.17|3644799|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_014124 (Pseudomonas putida plasmid pDK1, complete sequence) position: , mismatch: 9, identity: 0.719

atgctagctcactttccttatgtagacacata	CRISPR spacer
cagccagctcactttccttctgtaggaaggga	Protospacer
  **.************** *****. * . *

111. spacer 6.17|3644799|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_008275 (Pseudomonas putida MT53 plasmid pWW53, complete sequence) position: , mismatch: 9, identity: 0.719

atgctagctcactttccttatgtagacacata	CRISPR spacer
cagccagctcactttccttctgtaggaaggga	Protospacer
  **.************** *****. * . *

112. spacer 6.29|3645519|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to CP047036 (Rhodobacter sphaeroides strain DSM 158 plasmid pDx, complete sequence) position: , mismatch: 9, identity: 0.719

atacgaggtggagggcgcaacgatcccgacaa	CRISPR spacer
tcagcagggggagggcgcagcgatcccgtctc	Protospacer
 .*  *** **********.******** *

113. spacer 6.30|3645579|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MG592488 (Vibrio phage 1.115.A._10N.222.49.B11, partial genome) position: , mismatch: 9, identity: 0.719

tggatttgcttgctcaagtggcggggcttggc	CRISPR spacer
gagaactgcttgcgcaagtgacggggcttata	Protospacer
 .** .******* ******.********.

114. spacer 6.30|3645579|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MG592489 (Vibrio phage 1.115.B._10N.222.49.B11, partial genome) position: , mismatch: 9, identity: 0.719

tggatttgcttgctcaagtggcggggcttggc	CRISPR spacer
gagaactgcttgcgcaagtgacggggcttata	Protospacer
 .** .******* ******.********.

115. spacer 6.34|3645819|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MN694202 (Marine virus AFVG_250M1202, complete genome) position: , mismatch: 9, identity: 0.719

ctcttgcttgctatttttcatagtctcgctaa	CRISPR spacer
ctcttgcttgctattatccatagttccctgtt	Protospacer
*************** *.******..* .

116. spacer 6.47|3646599|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MK893987 (Staphylococcus phage PMBT8, complete genome) position: , mismatch: 9, identity: 0.719

gacaatttatctataaaagagattgacaagaa	CRISPR spacer
caagaaaaatataaaaaagagattgacaagat	Protospacer
 * .*   ** ** *****************

117. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135205 (Enterococcus faecium isolate E7171 plasmid 3) position: , mismatch: 9, identity: 0.719

acactagggaaaaagtagaagcacattattta	CRISPR spacer
ataaattagaaaaagaagaagcacagtatttg	Protospacer
*.*    .******* ********* *****.

118. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_011774 (Bacillus cereus G9842 plasmid pG9842_140, complete sequence) position: , mismatch: 9, identity: 0.719

acactagggaaaaagtagaagcacattattta	CRISPR spacer
atccataccaaaaagtaggatcacattattta	Protospacer
*. *  .  *********.* ***********

119. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP008815 (Enterococcus faecalis ATCC 29212 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

acactagggaaaaagtagaagcacattattta	CRISPR spacer
ataagttagaaaaagaagaagcacagtatttg	Protospacer
*.*    .******* ********* *****.

120. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MF498774 (Aeromonas phage AS-yj, partial genome) position: , mismatch: 9, identity: 0.719

acactagggaaaaagtagaagcacat---tattta	CRISPR spacer
tggctaaagaaaaagtagaagcacatgcacat---	Protospacer
  .***..******************   .**

121. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MH791398 (UNVERIFIED: Aeromonas phage Asswx_1, complete genome) position: , mismatch: 9, identity: 0.719

acactagggaaaaagtagaagcacat---tattta	CRISPR spacer
tggctaaagaaaaagtagaagcacatgcacat---	Protospacer
  .***..******************   .**

122. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MN871442 (UNVERIFIED: Aeromonas phage Aszh-1, complete genome) position: , mismatch: 9, identity: 0.719

acactagggaaaaagtagaagcacat---tattta	CRISPR spacer
tggctaaagaaaaagtagaagcacatgcacat---	Protospacer
  .***..******************   .**

123. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MN871441 (UNVERIFIED: Aeromonas phage AsSzw2, complete genome) position: , mismatch: 9, identity: 0.719

acactagggaaaaagtagaagcacat---tattta	CRISPR spacer
tggctaaagaaaaagtagaagcacatgcacat---	Protospacer
  .***..******************   .**

124. spacer 7.1|3896449|32|NC_015276|CRISPRCasFinder,CRT matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 9, identity: 0.719

gttatcaaaacgggtaacggaaagctctatat	CRISPR spacer
gggcctgagaccggtaacggaaagctcgatat	Protospacer
*   ...*.** *************** ****

125. spacer 7.7|3896809|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MN693605 (Marine virus AFVG_25M414, complete genome) position: , mismatch: 9, identity: 0.719

tatgaagttttttaaaggtaaagcggtcaagt	CRISPR spacer
tatgaatgtttttaaaggtaaagatcctcaat	Protospacer
******  ***************   .. *.*

126. spacer 7.10|3896989|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 9, identity: 0.719

ctggtcagtatgtcgaattaacaaaatacata	CRISPR spacer
taggtcaatatgtagaattaacaaaacctttt	Protospacer
. *****.***** ************. . *

127. spacer 7.10|3896989|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MT080596 (UNVERIFIED: Staphylococcus phage vB_SauM_EW42, complete genome) position: , mismatch: 9, identity: 0.719

ctggtcagtatgtcgaattaacaaaatacata	CRISPR spacer
ataattctcatgtcgaattagcaaaatactta	Protospacer
 *..*.  .***********.******** **

128. spacer 7.10|3896989|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MT080593 (UNVERIFIED: Staphylococcus phage vB_SauM_EW36, complete genome) position: , mismatch: 9, identity: 0.719

ctggtcagtatgtcgaattaacaaaatacata	CRISPR spacer
ataattctcatgtcgaattagcaaaatactta	Protospacer
 *..*.  .***********.******** **

129. spacer 7.11|3897049|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to AP013512 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G21, isolate: uvMED-CGR-C84-MedDCM-OCT-S29-C65) position: , mismatch: 9, identity: 0.719

ccaaagaatgtttaagagagttcatggtgaat	CRISPR spacer
ctaaagattgtttaagagagtttatatcatct	Protospacer
*.***** **************.**. ..  *

130. spacer 7.11|3897049|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MN693620 (Marine virus AFVG_250M617, complete genome) position: , mismatch: 9, identity: 0.719

ccaaagaatgtttaagagagttcatggtgaat	CRISPR spacer
aaacggattggttaagagagttcatggttgaa	Protospacer
  * .** ** ***************** .*

131. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028227 (Lactobacillus plantarum strain SRCM101187 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

132. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025691 (Lactobacillus plantarum strain IRG1 plasmid pIRG101, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

133. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021502 (Lactobacillus plantarum strain SRCM102022 plasmid pPL2022-1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

134. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021475 (Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-4, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

135. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016271 (Lactobacillus plantarum subsp. plantarum strain CGMCC 1.557 plasmid pLp1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

136. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024060 (Lactobacillus plantarum strain KACC 92189 plasmid unnamed2) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

137. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032360 (Lactobacillus plantarum strain ZFM55 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

138. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023303 (Lactobacillus plantarum strain pc-26 plasmid p.pc-2602, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

139. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032643 (Lactobacillus plantarum strain ZFM9 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

140. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035146 (Lactobacillus plantarum strain SRCM103357 plasmid unnamed3) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

141. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035146 (Lactobacillus plantarum strain SRCM103357 plasmid unnamed3) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

142. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028262 (Lactobacillus plantarum strain SRCM102737 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

143. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP048024 (Lactobacillus plantarum strain CACC 558 plasmid p2CACC558, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

144. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028223 (Lactobacillus plantarum strain SRCM101105 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

145. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028276 (Lactobacillus plantarum strain SRCM100995 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

146. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028244 (Lactobacillus plantarum strain SRCM101518 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

147. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054261 (Lactobacillus plantarum strain TCI507 plasmid unnamed2) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
acagatatttttgacttggaggacttaccaaa	Protospacer
 .*.   .************* * ********

148. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MK368614 (Vibrio phage 2 TSL-2019, complete genome) position: , mismatch: 9, identity: 0.719

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
gtgttcctttttgaattagagtagttaccaat	Protospacer
 *. . *.****** **.*************

149. spacer 7.29|3898129|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NC_018069 (Solibacillus silvestris StLB046 plasmid pSSIL1, complete sequence) position: , mismatch: 9, identity: 0.719

gaaaagacctgtaatgttattttttgataaac	CRISPR spacer
acggagaactgtaatgttattatttgaatgac	Protospacer
. ..*** ************* *****  .**

150. spacer 7.31|3898249|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MN047793 (Xanthomonas phage Xoo-sp13, complete genome) position: , mismatch: 9, identity: 0.719

agcatttcgcttttcaattagagttatatact	CRISPR spacer
atccacacgcttttctattagagttaaataaa	Protospacer
* *  . ******** ********** ***

151. spacer 7.36|3898549|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to CP016196 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence) position: , mismatch: 9, identity: 0.719

tgcgtcgggcatgttttttatcaattcgtaaa	CRISPR spacer
agggataaacatgttttttatcagttggtaaa	Protospacer
 * * ....**************.** *****

152. spacer 2.41|696846|35|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to AP014136 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C47-MedDCM-OCT-S34-C10, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 10, identity: 0.714

gtgctagaacttgaagttgaagttgaaaatgtgtt	CRISPR spacer
aagctagaacttggagttgaagttgaaataccaac	Protospacer
. ***********.**************   .. .

153. spacer 2.41|696846|35|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to AP014135 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C47-MedDCM-OCT-S32-C28, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 10, identity: 0.714

gtgctagaacttgaagttgaagttgaaaatgtgtt	CRISPR spacer
aagctagaacttggagttgaagttgaaataccaac	Protospacer
. ***********.**************   .. .

154. spacer 2.41|696846|35|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012203 (Alteromonas macleodii strain HOT1A3 plasmid pAM1A3, complete sequence) position: , mismatch: 10, identity: 0.714

gtgctagaacttgaagttgaagttgaaaatgtgtt	CRISPR spacer
gaaatgtctgttggggttgaagttgaaaatgtgtt	Protospacer
* . *.    ***..********************

155. spacer 2.41|696846|35|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039853 (Salinimonas sp. KX18D6 plasmid plas12, complete sequence) position: , mismatch: 10, identity: 0.714

gtgctagaacttgaagttgaagttgaaaatgtgtt	CRISPR spacer
gaaatgtctgttggggttgaagttgaaaatgtgtt	Protospacer
* . *.    ***..********************

156. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

157. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

158. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

159. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

160. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

161. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

162. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

163. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

164. spacer 6.9|3644317|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 10, identity: 0.688

tggttcaccatcccctacttcaccttcaaaat	CRISPR spacer
ctgaacaccatcccttccttcaccttcaccga	Protospacer
. *  *********.* ***********  .

165. spacer 6.39|3646119|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 10, identity: 0.688

cccagcaaaaacgcttcattcgctttttgttg	CRISPR spacer
gttggcaaaaacgctttattagcttttcttga	Protospacer
 ...************.*** ******. * .

166. spacer 6.47|3646599|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to AB711120 (Bacillus phage PM1 DNA, complete genome) position: , mismatch: 10, identity: 0.688

gacaatttatctataaaagagattgacaagaa	CRISPR spacer
cacaatttaactataacagagattcggcatct	Protospacer
 ******** ****** ******* .  *

167. spacer 6.49|3646719|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_029073 (Geobacillus virus E3, complete genome) position: , mismatch: 10, identity: 0.688

acactagggaaaaagtagaagcacattattta	CRISPR spacer
cggtaaataaaaaagtaaaagcacaatattta	Protospacer
  .. *. .********.******* ******

168. spacer 7.9|3896929|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NC_017472 (Lactobacillus amylovorus GRL1118 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.688

ccgatttaacaactaaaaccgtgtacacaatc	CRISPR spacer
attatttaacagcttaaaccgtgtacctgttt	Protospacer
 . ********.** *********** .. *.

169. spacer 7.21|3897649|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to MN562221 (Photobacterium phage PDCC-1, complete genome) position: , mismatch: 10, identity: 0.688

ctaacgccttttgacttggagtagttaccaaa	CRISPR spacer
tgttccttttttgaattagagtagttaccaat	Protospacer
.   * ..****** **.*************

170. spacer 6.24|3645219|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to NC_014838 (Pantoea sp. At-9b plasmid pPAT9B01, complete sequence) position: , mismatch: 11, identity: 0.656

tctaccataacaaaatcctcttatatcgttat	CRISPR spacer
agacgcataacaaaatcatctcatatcgaaca	Protospacer
     ************ ***.******

171. spacer 6.29|3645519|32|NC_015276|PILER-CR,CRISPRCasFinder,CRT matches to MH067977 (Arthrobacter sp. strain ANT_H8 plasmid pA8H1, complete sequence) position: , mismatch: 11, identity: 0.656

atacgaggtggagggcgcaacgatcccgacaa	CRISPR spacer
tctagaggtggagggcccaccgatccctctcc	Protospacer
 .  ************ ** *******  .

172. spacer 7.23|3897769|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051294 (Mesorhizobium sp. NZP2077 plasmid pMSNZP2077A, complete sequence) position: , mismatch: 11, identity: 0.656

tttacgtgatgatgctcgctccggtgtgaaat	CRISPR spacer
gcgtcgtgatgatgcgcgccccggtgtccggc	Protospacer
 .  *********** ***.*******  ...

173. spacer 7.23|3897769|32|NC_015276|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033363 (Mesorhizobium sp. NZP2077 plasmid pMSNZP2077NSa, complete sequence) position: , mismatch: 11, identity: 0.656

tttacgtgatgatgctcgctccggtgtgaaat	CRISPR spacer
gcgtcgtgatgatgcgcgccccggtgtccggc	Protospacer
 .  *********** ***.*******  ...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

636192 : 645287

uncultured_Mediterranean_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013659808.1\|636192_637560_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A0N7G7I9	Chrysochromulina_ericina_virus	4.2e-31	36.7
WP_013659809.1\|637561_639391_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1I1B8	Acanthocystis_turfacea_Chlorella_virus	4.9e-128	44.8
WP_013659810.1\|639454_640150_+	acylneuraminate cytidylyltransferase family protein	A0A1B1IVD3	uncultured_Mediterranean_phage	2.7e-10	35.9
WP_013659811.1\|640146_642399_+	N-acetylneuraminate synthase family protein	A0A1B1IVE2	uncultured_Mediterranean_phage	3.1e-31	34.4
WP_013659812.1\|642415_643429_+	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	K7Y9E1	Megavirus	1.2e-48	36.9
WP_041647740.1\|643425_644601_+	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	A0A2K9L0G1	Tupanvirus	3.7e-28	31.7
WP_013659814.1\|644600_645287_+	pseudaminic acid cytidylyltransferase	A0A1B1IVD3	uncultured_Mediterranean_phage	3.8e-09	39.8

DBSCAN-SWA_2

1133108 : 1142675

Vibrio_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013660187.1\|1133108_1134509_-	PhoH family protein	A0A2I7SAD7	Vibrio_phage	1.6e-102	45.5
WP_013660188.1\|1134848_1136681_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	4.1e-34	34.5
WP_013660189.1\|1136790_1138854_-	DNA primase	A0A1S5RG58	Helicobacter_phage	6.2e-47	35.5
WP_013660190.1\|1138876_1139323_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	2.2e-21	42.4
WP_013660191.1\|1139469_1139685_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_013660192.1\|1140078_1141113_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.7e-106	56.8
WP_013660193.1\|1141228_1141582_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_013660194.1\|1141559_1142675_-\|tRNA	tRNA nucleotidyltransferase	A0A2I7SAR1	Vibrio_phage	1.1e-53	44.8

DBSCAN-SWA_3

1988696 : 2052137

Vibrio_virus(23.68%)

protease,portal,tail,plate,transposase,terminase,holin,head,capsid,tRNA,integrase

attL 1992185:1992200|attR 2054529:2054544

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013660961.1\|1988696_1989083_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	6.4e-22	42.2
WP_013660962.1\|1989139_1990105_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	5.5e-70	49.4
WP_041647842.1\|1990395_1994259_+	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	4.6e-51	25.5
1992185:1992200	attL	NA	NA	NA	NA
WP_013660964.1\|1994287_1995130_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_013660965.1\|1995454_1997755_+	EAL domain-containing protein	A0A127AWB9	Bacillus_phage	3.9e-13	29.0
WP_041648479.1\|1997840_1998983_-	PQQ-dependent sugar dehydrogenase	NA	NA	NA	NA
WP_013660967.1\|1999238_2000189_-	transaldolase	A0A0E3G6C9	Synechococcus_phage	4.6e-13	36.4
WP_013660968.1\|2000202_2001249_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_013660969.1\|2001441_2002584_+\|integrase	site-specific integrase	I6NSG1	Burkholderia_phage	9.1e-56	37.9
WP_013660970.1\|2002561_2002921_-	pyocin activator PrtN family protein	NA	NA	NA	NA
WP_013660971.1\|2002910_2003141_-	hypothetical protein	NA	NA	NA	NA
WP_013660972.1\|2003143_2003575_-	hypothetical protein	NA	NA	NA	NA
WP_013660973.1\|2003594_2003783_-	carbon storage regulator CsrA	H2BD56	Pseudomonas_phage	1.1e-08	56.9
WP_013660974.1\|2004044_2005169_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_013660975.1\|2005168_2005717_+	DUF4411 family protein	NA	NA	NA	NA
WP_013660976.1\|2005713_2006364_-	LexA family transcriptional regulator	K7P850	Enterobacteria_phage	5.9e-52	51.2
WP_013660977.1\|2006477_2006690_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013660978.1\|2006737_2007178_+	phage regulatory CII family protein	NA	NA	NA	NA
WP_013660979.1\|2007181_2007871_+	DUF2786 domain-containing protein	L7P7W8	Pseudomonas_phage	1.0e-06	28.7
WP_013660980.1\|2007867_2008806_+	hypothetical protein	A0A068C8G6	Acinetobacter_phage	6.8e-25	45.1
WP_013660981.1\|2008815_2009163_+	hypothetical protein	NA	NA	NA	NA
WP_013660982.1\|2009165_2009360_+	hypothetical protein	NA	NA	NA	NA
WP_013660983.1\|2009332_2009860_+	hypothetical protein	NA	NA	NA	NA
WP_013660984.1\|2009856_2011023_+\|integrase	site-specific integrase	A0A2D1GND4	Pseudomonas_phage	4.5e-50	34.3
WP_013660985.1\|2011165_2012524_+	hypothetical protein	NA	NA	NA	NA
WP_013660987.1\|2013128_2013728_-	hypothetical protein	NA	NA	NA	NA
WP_013660988.1\|2014093_2014669_+	KilA-N domain-containing protein	A0A2H4IZE1	uncultured_Caudovirales_phage	1.8e-20	40.8
WP_041647849.1\|2014740_2015184_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A218MND2	uncultured_virus	3.0e-31	49.7
WP_013660990.1\|2015180_2016452_+	translesion error-prone DNA polymerase V subunit UmuC	I6RSM4	Salmonella_phage	3.9e-132	55.9
WP_013660991.1\|2016566_2016827_+	hypothetical protein	NA	NA	NA	NA
WP_013660992.1\|2017191_2017485_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_013660993.1\|2017481_2018000_+	hypothetical protein	A0A1B2ANT4	Pseudoalteromonas_phage	5.1e-14	35.5
WP_013660994.1\|2017996_2018164_+	hypothetical protein	NA	NA	NA	NA
WP_013660995.1\|2018345_2018825_+	DUF1441 family protein	A5LH26	Enterobacteria_phage	2.3e-21	39.7
WP_013660996.1\|2018824_2020876_+\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	1.1e-163	44.5
WP_013660997.1\|2020872_2021073_+	hypothetical protein	NA	NA	NA	NA
WP_013660998.1\|2021072_2022572_+\|portal	phage portal protein	A0A219Y9V7	Aeromonas_phage	9.6e-98	40.6
WP_013660999.1\|2022600_2023629_+\|protease	Clp protease ClpP	A0A2I7SCY8	Paenibacillus_phage	1.1e-20	34.0
WP_013661000.1\|2023662_2024025_+\|head	head decoration protein	R9TP46	Rhizobium_phage	2.9e-08	37.3
WP_013661001.1\|2024034_2025054_+\|capsid	major capsid protein	A0A0A8ILA9	Aurantimonas_phage	7.9e-43	34.6
WP_013661002.1\|2025053_2025419_+	hypothetical protein	NA	NA	NA	NA
WP_013661003.1\|2025408_2025900_+	hypothetical protein	NA	NA	NA	NA
WP_013661004.1\|2025896_2026436_+	hypothetical protein	NA	NA	NA	NA
WP_013661005.1\|2026432_2027098_+\|plate	phage baseplate assembly protein V	A2I2X5	Vibrio_virus	7.7e-39	44.8
WP_013661006.1\|2027111_2027309_+	hypothetical protein	A0A0H4ISU1	Pseudoalteromonas_phage	8.1e-05	48.1
WP_013661007.1\|2027308_2027650_+	hypothetical protein	B0ZSF8	Halomonas_phage	1.6e-16	44.2
WP_013661008.1\|2027636_2028638_+\|plate	baseplate J/gp47 family protein	Q6R4V6	Vibrio_virus	4.6e-72	43.3
WP_013661009.1\|2028597_2029350_+\|tail	phage tail protein I	Q6R4V7	Vibrio_virus	1.6e-37	41.4
WP_013661010.1\|2029346_2029883_+	hypothetical protein	D4HTV6	Vibrio_phage	2.1e-34	46.9
WP_013661011.1\|2029887_2030589_+	hypothetical protein	NA	NA	NA	NA
WP_013661012.1\|2030585_2030999_+	hypothetical protein	NA	NA	NA	NA
WP_013661013.1\|2031081_2031270_+	hypothetical protein	NA	NA	NA	NA
WP_013661014.1\|2031269_2032439_+\|tail	tail protein	Q6R4W2	Vibrio_virus	1.7e-110	55.0
WP_013661015.1\|2032440_2032947_+\|tail	phage major tail tube protein	Q6R4W3	Vibrio_virus	1.8e-48	56.0
WP_013661016.1\|2033002_2033572_+\|tail	phage tail assembly protein	Q6R4W4	Vibrio_virus	8.3e-26	39.3
WP_041647855.1\|2033703_2036550_+\|tail	phage tail tape measure protein	A2I2Y1	Vibrio_virus	7.7e-80	43.9
WP_013661018.1\|2036751_2037699_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.9e-39	35.7
WP_013661019.1\|2038076_2038835_+	hypothetical protein	NA	NA	NA	NA
WP_013661020.1\|2038996_2039644_+	hypothetical protein	NA	NA	NA	NA
WP_013661021.1\|2039782_2040175_+\|tail	phage tail protein	B0ZSH2	Halomonas_phage	9.4e-29	49.2
WP_013661022.1\|2040158_2040368_+\|tail	tail protein X	A2I2Y3	Vibrio_virus	1.9e-12	47.8
WP_013661023.1\|2040358_2041369_+	hypothetical protein	A2I2Y5	Vibrio_virus	5.3e-92	51.1
WP_013661024.1\|2041601_2041757_+	hypothetical protein	NA	NA	NA	NA
WP_013661026.1\|2041943_2042438_+	hypothetical protein	NA	NA	NA	NA
WP_013661027.1\|2042526_2043474_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.2e-40	36.4
WP_013661028.1\|2044744_2045893_-	hypothetical protein	NA	NA	NA	NA
WP_013661029.1\|2046017_2046878_+	BRCT domain-containing protein	NA	NA	NA	NA
WP_013661030.1\|2047243_2047810_+	KilA-N domain-containing protein	I6R977	Salmonella_phage	3.6e-21	54.0
WP_013661031.1\|2047863_2048721_-	endonuclease	A0A2P0VMP9	Tetraselmis_virus	3.8e-22	34.8
WP_013661032.1\|2048817_2048985_-	hypothetical protein	NA	NA	NA	NA
WP_013661033.1\|2049206_2049410_-	hypothetical protein	NA	NA	NA	NA
WP_013661034.1\|2049542_2050379_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_013661035.1\|2050359_2051229_-	hypothetical protein	NA	NA	NA	NA
WP_041647858.1\|2051834_2052137_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
2054529:2054544	attR	NA	NA	NA	NA

DBSCAN-SWA_4

4653444 : 4665729

Vibrio_phage(33.33%)

tRNA,tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_190273440.1\|4653444_4653603_-\|tail	phage tail protein	NA	NA	NA	NA
WP_013663292.1\|4653619_4653991_-\|tail	phage tail protein	NA	NA	NA	NA
WP_013663293.1\|4653990_4656009_-	hypothetical protein	K7RVY9	Vibrio_phage	1.0e-25	41.8
WP_013663294.1\|4656146_4656398_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_013663295.1\|4656610_4657108_-\|tail	phage major tail tube protein	NA	NA	NA	NA
WP_013663296.1\|4657110_4658205_-\|tail	tail sheath protein	A7YGT4	Campylobacter_phage	3.2e-42	30.5
WP_013663297.1\|4658217_4658679_-	hypothetical protein	NA	NA	NA	NA
WP_013663298.1\|4658678_4659479_-	hypothetical protein	NA	NA	NA	NA
WP_013663299.1\|4659475_4659985_-	hypothetical protein	NA	NA	NA	NA
WP_013663300.1\|4659972_4660545_-\|tail	phage tail protein I	NA	NA	NA	NA
WP_013663301.1\|4660541_4661354_-\|plate	baseplate J/gp47 family protein	A0A0M4REB7	Salmonella_phage	2.4e-18	26.0
WP_013663302.1\|4661350_4661662_-	GPW/gp25 family protein	Q8H9N4	Vibrio_phage	1.0e-06	42.6
WP_013663303.1\|4661658_4662198_-\|plate	phage baseplate assembly protein V	K4NXJ5	Burkholderia_phage	7.9e-10	32.0
WP_013663304.1\|4662384_4662846_+	hypothetical protein	M4R2L2	Vibrio_phage	8.5e-05	38.0
WP_013663305.1\|4662848_4663091_+	hypothetical protein	NA	NA	NA	NA
WP_013663307.1\|4663348_4663552_-	hypothetical protein	NA	NA	NA	NA
WP_148231147.1\|4663613_4664027_-	lysozyme	A0A088FB05	Idiomarinaceae_phage	1.2e-26	49.2
WP_190273414.1\|4664236_4664917_+	helix-turn-helix transcriptional regulator	A0A125RN88	Pseudomonas_phage	1.1e-24	33.3
WP_013663310.1\|4664946_4665729_-\|tRNA	tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA	S4VW33	Pandoravirus	2.2e-13	29.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015276

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection