CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015387	Marinithermus hydrothermalis DSM 14884, complete sequence	10 crisprs	DinG,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas1,cas2,cas3,cas5,cas8c,cas7b,cas4,c2c10_CAS-V-U3,Cas14u_CAS-V,csa3,DEDDh,WYL,cas8e,cse2gr11,cas7,cas6e,Cas9_archaeal,cmr6gr7,cmr5gr11,cmr4gr7,cmr1gr7,cmr3gr5,c2c9_V-U4,cas8b1	2	64	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015387_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_1

193086-193283

TypeIII

III-A

Consensus_repeat	Method
CAGAGTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACCA	PILER-CR
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAAC	CRISPRCasFinder

2 spacers

cas2,cas1,csx1,cas10,csm2gr11,csm3gr7

The CRISPR arrays of NC_015387_1

>merge|NC_015387|1|193086-193283|PILER-CR,CRISPRCasFinder
CAGAGTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACCAGGTCCTCCCGGGCCTCGGTGCGGGTCTCCACCCCCAGCACGTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACCACTTGGCAGGTCCTTCAGGAGCGTAATACTGCAACTCCTGAGTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACAA

>NC_015387|1|1|193086-193283|PILER-CR
CAGAGTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACCA	GGTCCTCCCGGGCCTCGGTGCGGGTCTCCACCCCCAGCAC
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACCACTTG	GCAGGTCCTTCAGGAGCGTAATACTGCAACTCCTGA
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACAA

>NC_015387|1|1|193090-193281|CRISPRCasFinder
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAAC	CAGGTCCTCCCGGGCCTCGGTGCGGGTCTCCACCCCCAGCAC
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAAC	CACTTGGCAGGTCCTTCAGGAGCGTAATACTGCAACTCCTGA
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013703013.1\|198383_198836_+\|IS607-family-transposase	unknown	unknown	gnl\|CDD\|239738
NC_015387.1\|WP_013703014.1\|198876_199911_+\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NC_015387.1\|WP_013703010.1\|195919_197359_+\|RtcB-family-protein	unknown	unknown	gnl\|CDD\|376465
NC_015387.1\|WP_013703007.1\|193710_194799_+\|DUF1887-family-protein	unknown	unknown	gnl\|CDD\|312526
NC_015387.1\|WP_169311727.1\|191661_192600_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
NC_015387.1\|WP_013703006.1\|193369_193600_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013703008.1\|194842_195493_+\|PIG-L-family-deacetylase	unknown	unknown	gnl\|CDD\|225031
NC_015387.1\|WP_013702998.1\|184785_185205_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|187778
NC_015387.1\|WP_013703003.1\|189381_189936_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271199
NC_015387.1\|WP_169311726.1\|191417_191711_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271179
NC_015387.1\|WP_083804401.1\|189871_191398_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_015387.1\|WP_013703011.1\|197374_197995_+\|HAD-family-phosphatase	unknown	unknown	gnl\|CDD\|319790
NC_015387.1\|WP_013703012.1\|197996_198341_+\|DUF3208-domain-containing-protein	unknown	unknown	gnl\|CDD\|371553
NC_015387.1\|WP_041658141.1\|185204_187601_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NC_015387.1\|WP_013703009.1\|195489_195909_+\|archease	unknown	unknown	gnl\|CDD\|376680
NC_015387.1\|WP_041657745.1\|187780_188998_+\|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	gnl\|CDD\|274263
NC_015387.1\|WP_013702997.1\|184060_184786_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_015387.1\|WP_148230385.1\|189000_189255_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_041658145.1\|192608_192872_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0081_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_015387.1\|WP_041658151.1\|199978_200188_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240615

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013703013.1\|198383_198836_+\|IS607-family-transposase	gnl\|CDD\|239738	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.	1.12476e-25
NC_015387.1\|WP_013703014.1\|198876_199911_+\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	7.94704e-137
NC_015387.1\|WP_013703010.1\|195919_197359_+\|RtcB-family-protein	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	0
NC_015387.1\|WP_013703007.1\|193710_194799_+\|DUF1887-family-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	0.000145679
NC_015387.1\|WP_169311727.1\|191661_192600_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.97006e-60
NC_015387.1\|WP_013703008.1\|194842_195493_+\|PIG-L-family-deacetylase	gnl\|CDD\|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	7.42098e-36
NC_015387.1\|WP_013702998.1\|184785_185205_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|187778	cd09647, Csm2_III-A, CRISPR/Cas system-associated protein Csm2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-A.	4.93709e-10
NC_015387.1\|WP_013703003.1\|189381_189936_+\|hypothetical-protein	gnl\|CDD\|271199	cd04791, LanC_SerThrkinase, Lanthionine synthetase C-like domain associated with serine/threonine kinases. Some members of this subgroup lack the zinc binding site and the active site residues, and therefore are most likely inactive. The function of this domain is unknown.	3.40033e-14
NC_015387.1\|WP_169311726.1\|191417_191711_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271179	cd00798, INT_XerDC_C, XerD and XerC integrases, C-terminal catalytic domains. XerDC-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination of chromosomal replication, and stable plasmid inheritance. They share the same fold in their catalytic domain containing six conserved active site residues and the overall reaction mechanism with the DNA breaking-rejoining enzyme superfamily. In Escherichia coli, the Xer site-specific recombination system acts to convert dimeric chromosomes, which are formed by homologous recombination to monomers. Two related recombinases, XerC and XerD, bind cooperatively to a recombination site present in the E. coli chromosome. Each recombinase catalyzes the exchange of one pair of DNA strand in a reaction that proceeds through a Holliday junction intermediate. These enzymes can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves, and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	4.60594e-21
NC_015387.1\|WP_083804401.1\|189871_191398_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.68022e-56
NC_015387.1\|WP_013703011.1\|197374_197995_+\|HAD-family-phosphatase	gnl\|CDD\|319790	cd02603, HAD_sEH-N_like, N-terminal lipase phosphatase domain of human soluble epoxide hydrolase, Escherichia coli YihX/HAD4 alpha-D-glucose 1-phosphate phosphatase, and related domains, may be inactive. This family includes the N-terminal phosphatase domain of human soluble epoxide hydrolase (sEH). sEH is a bifunctional enzyme with two distinct enzyme activities, the C-terminal domain has epoxide hydrolysis activity and the N-terminal domain (Ntermphos), which belongs to this family, has lipid phosphatase activity. The latter prefers mono-phosphate esters, and lysophosphatidic acids (LPAs) are the best natural substrates found to date. In addition this family includes Gallus gallus sEH and Xenopus sEH which appears to lack phosphatase activity, and Escherichia coli YihX/HAD4 which selectively hydrolyzes alpha-Glucose-1-P, phosphatase, has significant phosphatase activity against pyridoxal phosphate, and has low beta phosphoglucomutase activity. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	9.45724e-47
NC_015387.1\|WP_013703012.1\|197996_198341_+\|DUF3208-domain-containing-protein	gnl\|CDD\|371553	pfam11482, DUF3208, Protein of unknown function (DUF3208). This bacterial family of proteins has no known function.	1.03729e-46
NC_015387.1\|WP_041658141.1\|185204_187601_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	1.96593e-159
NC_015387.1\|WP_013703009.1\|195489_195909_+\|archease	gnl\|CDD\|376680	pfam01951, Archease, Archease protein family (MTH1598/TM1083). This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.	5.21696e-49
NC_015387.1\|WP_041657745.1\|187780_188998_+\|TIGR02710-family-CRISPR-associated-protein	gnl\|CDD\|274263	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family. Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Archaea), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	6.73152e-95
NC_015387.1\|WP_013702997.1\|184060_184786_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.95361e-92
NC_015387.1\|WP_041658145.1\|192608_192872_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.70346e-26
NC_015387.1\|WP_041658151.1\|199978_200188_-\|hypothetical-protein	gnl\|CDD\|240615	cd12222, Caa3-IV, Caa3-Type Cytochrome Oxidase subunit 4 interacts with cyt c subunits I/III. Cytochrome c oxidase, a haem copper oxidase superfamily member, is the final step in the electron-transport chain, linking O2 reduction to transmembrane pumping in mitochondria and aerobic prokaryotes. Cytochrome c oxidase (aka Complex IV) catalyzes the reduction of O2 to 2H2O, and acts downstream of Complexes I-III: NADH-Q oxidoreductase, succinate-Q reductase, and Q-cytochrome c oxidoreductase. In Thermus thermophilus caa3-oxidase is comprised of subunit (SU) I/III, a fusion of classical SU I and SUIII, and IIc as well SU IV, which is composed of 2 connected transmembrane helices that interface with SU I/III.	3.14388e-20

>NC_015387.1|WP_041658145.1|192608_192872_+|CRISPR-associated-endonuclease-Cas2
MLYTVTYDVPDDRRRVKIANLLKSYGERVQLSVFECWLNASEVEALKQRLERVMEPSEDSVRIYSVRGAVQVLGVGKITEEENAFIV
>NC_015387.1|WP_169311727.1|191661_192600_+|CRISPR-associated-endonuclease-Cas1
MWGVIRCQSSRPARRATASPWPPRSGPRRASPGWAWRCGSRCRGSWELLQVPVLQPLVAGPLGRGGEDHHPLLVPLAPDPDGVGDPVLVGDVRVGEVQGLGEAQARAVEEGQKGPVPEAHPGGAVLVGGLERLRGVEGIATRTYFEGLASGLGPYGFGGRSRRPPRDAPNAALSYGYALLLARAWLAVVLAGLHPEVGFLHVEGRRNPALALDLMEEFRVPVVDVTVLRAFQEGVLDPAQHFEARGGGVYLNEGGRKRLVRVLAHRLNQEVRHPDGSKRTTYAGMIAYQGVRLAAAVEGRRAYHPFFLEASR
>NC_015387.1|WP_169311726.1|191417_191711_-|tyrosine-type-recombinase/integrase
MARRAGLEDWHRITPHKLRHSYASALVEAGRGINEVKELLGHSSISTTQVYVHVSQRRLEEAARTMPDVIGCPSIRRLEQGARSPFPQASSVKRWRT
>NC_015387.1|WP_083804401.1|189871_191398_+|ABC-transporter-ATP-binding-protein
MRTLWTLLEGRRGEFLRLLAVSSLVSAAEALLHPLMLKWLFDEAVVTQDFRRFGLLGLAYLAAGLSLIALFWAVSLWQKAFVNRVVLEVEGRLLAKALRLDWRDFSREGAGAFVSRVHQDVLEGLVPAVSLLVAVARQALAALAFLGVLLYLSWQATLALAILVPPLLWVAQRVGTRVRRAAEDEREGEARYLEVLSQSLKAFRALRGLPRLLRPTLAANREALGTYLDDTYRSHRLMEAQQAWSDVFMNLANTLALIVGGYFVLARVLSFGGYLAFVNAFWRAVDNTFALLRRVPEFHRHAQVLERIHGLLSSAPTPYAQPAAEARLEGVRLAYAGGALLELPQVEIRPGERLLLVGPNGAGKSTLLHVLSGYLAPQEGEVKLPARVAALTAPPELPPLTVRELVPDARLRRELGLEGLEDHRPEALSSGQRQRAAIGALLCEEADLYLLDEPLANLDPESREGVLDLILRRTAGKALVVVLHGDEALHNRFDRVVELAGPQVPDPR
>NC_015387.1|WP_013703003.1|189381_189936_+|hypothetical-protein
MTCHSGVETLRFLGLTLLASASLPRPVHLVLDAPWGFALWGLAQLPRPCLDLSRKYSVLPGHLFGVAGIIDTLLDAYLLTREPIYLARLERQLEGLRTLHLFEPSVCASLLPQGRTLEGLAAPGEGLLRVSCDFATGCAGVLRVLHRVVNPGPADFMLDEVTPDEDVMDPSGGAQGRIPAPAGG
>NC_015387.1|WP_148230385.1|189000_189255_+|hypothetical-protein
MKTLDARWAAYKAIHREKGQAEAQRYYREEVWPLVREAWREHPRVPEEMPSFAASIHTLGRSPEATILAILGTRAARAGGAKHP
>NC_015387.1|WP_041657745.1|187780_188998_+|TIGR02710-family-CRISPR-associated-protein
MQQGEVPQVLIATVGQTPDPVLASLMEHAPDGVIFIASQDSHPTAALILSEFKRELKHHTILIEEPESLTESYQAARKALKKAKEWEARVILAEITGGTKPMIAGLALALTGQGVTFSYVGGTRRDEAGRVVSGHEKIRLLEDPTTRYYTQEWSAFRQAWNAGRMLEAQAWLERILSRPLTPSEERFHRHLLGITRGMDAWDRFQHAEALERFRAHLEPALAVAEAWHHGAKVRVLTALEAAQGFLERIVQAKGKPVPELLQDLLANAERRAQAGRYDDALARLYRAVELAAEVDLYERHQLWLRKPDAWPQGVPEYLKERARGMLGLKEVLDLAFDLDLHFGASGTLAQVLRGDYERKLRPLLQRRHESILAHGTRPVTREDYEKMRDYLHSLGLEPAPEWPRW
>NC_015387.1|WP_041658141.1|185204_187601_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MPDPVYEAALAGLLHDVGKLYQRAYWNHPPPELPDRTHTAYTAWFVQRHRQAFANAGLEPDRLAHDAAHHHLRTPKGYAPDTPLAWTVYYADNYAGQEDNEEPHTPTTPLTPVFQRVSLSGPPKASGLGYDLAPHTPNAAYPSAHPNVRPEAYAQLAERLDERMLELARQDADLKALLANLTAFLQEVAWCVPSNTQSEPDIALFDHLRLTAAISAALWAYHAETDGQVTPEGLEREVEAKFLLVLGDLGGIQQHIYRIQSAQTGTGGIAKRLRARSLEVALATEALAFDVLARVGLPPLNRVMSAGGRFYLLLPNTPTAHKALEAARAAWEAWALGEGATLVPHLAAHAFPPAGFRAFPEVLQAAHKALAQAKARPFATQLHTPYPFGEAALRPCAACGVRPAVRDEAGALCRGCQRDQEVGKRLPRETVIALFAERADYAFPGVPVALGKGGAYHLRAHPNPAPSATPFEVRPLLGHLPTVQDAQRALPEGTDYAAWLEQQGLAGEEDDPNEGLSPAPERPLTFGELAALSEGVPYLGVLMLDADRMGEVFSRGFAWAETDYATPSRIASLSRMLEQFFAVEVPNLIRHPERYAQRLGWGARATWKQRRYPLIYSVYAGGDDVFLLGPWDAVLEFALDLERLYRLYTQNPTFTLSGGFVLVRPKTPVPHLAASAHAAEKAAKHAGRDRLSVFGHPVRWADLGSLAERAEALAHRFEEGVPRGMAYRLLDLWRLWRRWDEAQDPEGLRYKPQLHYLFRREDLAAQRPFLEPLFNHQSLEMRHLPVWVQWATYKTRGK
>NC_015387.1|WP_013702998.1|184785_185205_-|type-III-A-CRISPR-associated-protein-Csm2
MGKAKVYYQDKTKQRLRADLFSEEAYRDAQRLVKARVATTQVRRYFGEIRALQARYNVLKHEKGAEAAFEEIRPYLGLLKAKAYYGRRNNNNRPNDMFTLSTFLTECLDGVEDPKSFEAMVKYVEAVVAYFTPDAERRS
>NC_015387.1|WP_013702997.1|184060_184786_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MRLLKLKVIRGELEAKTGLRIGGSREGLEIGGVDNPVIRNPLTGEPYVPGSSIKGKMRSLIEWSLGDEYLVDDTKHTHSCTRADCPVCRVFGSTAADSRPDQGVRGPTRLIVRDAYLTPASRQALQEMNLERGTLFTEIKQEVFIPRLGGDANPRTMERVPAGTRFEFEMVYKVFDTGDGGQTDEQYFEEIVQKGLRLLELDALGGSTSRGYGQIRFRNLEILEIDAQTGQETRLEPVREG
>NC_015387.1|WP_013703006.1|193369_193600_+|hypothetical-protein
MHDDHENKQTDEEKKLHQELEEALKDLYELIDLRESMSGGTVTIGKKPLGNFADHPEIHEAHRTPKKNEKNEEEES
>NC_015387.1|WP_013703007.1|193710_194799_+|DUF1887-family-protein
MGILTRYLAKAMERARYDLLAAGRYAADIPEFSLHVEANNLEAARHALQEALEERVLESLRLGLPLPELDGLTLGPTTPKAERFRQLVLELWQMIQGEAPPEEAPEAPPPPKRAGPNTLEEWLASRGIKIQRRPTEESEEDREREKVLARLALFLGDRYPTLTRVYEKLKQSLSTKRQFQLSLTDASQEEISNSTQFCTSLKQYALLTSYHYKSEERRLRAKASTEGWVQNFLTGGWLESYVMQKIQKALRSKNLPHEVARGLQVTLPNGDQTELDVLVLVQGRVFWFETKTGDFQAHIAKYSKLKKTLGLSAKESFLVLLGVDKARARELSALHNVTVVNQATFLDAFLEALGLVETPAEA
>NC_015387.1|WP_013703008.1|194842_195493_+|PIG-L-family-deacetylase
MDLLLILPHPDDEVFGAGGTLIQYAERGLKTGLITLTRGDQGRTLGLCTQDELPQVREAELRRSAERLGIQHLEVHTYPDRGVAEHPEITEMLVDRLRALKPRAVLTFPPNGINGHPDHVATSRWVTQAVQQSGIQTRLYYYAPPEPYPGHEAGYLPPTHTRRIPPEILLRKLNAMAQHKTQALSVLNFMDRFPHRLAVETFHLVGYTGPEQHELI
>NC_015387.1|WP_013703009.1|195489_195909_+|archease
MIRMLDHTADVGFEVRAPTREALFETAREGLLRLMFQHPPTQGSATREVTLQAPDLEFLLVRWLNELIYLVQTAGFVPARAAITITEDAQGFTLRARLEGQPFDAEAMGWQGEIKSATFHGLEVRPETSGWWARVVLDV
>NC_015387.1|WP_013703010.1|195919_197359_+|RtcB-family-protein
MDNVPFERLDRYTYRIPRHGKMWVDAVFYANDEILAQLEAEGYASLKQLVNVATLPGIVGPALAMPDIHWGYGFPIGGVAAFDPTAGGVVSPGGVGFDINCGVRLLTTRLTREDLEPRKTRLADALYRRVPAGVGSARRDVRWSPKDLKTVLREGARALVAQGFGEAADLERIESGGRLPLADPDRVSARALERGGPQLGTLGSGNHFLEVQYVDEVYDPEAAEAYGLWVGQVTVLIHTGSRGLGHQVCQDYVERFLQAARRYGIELVDRQLAAAPIESPEGQDYLHAMAAAANFAFANRQLITHNVRLAFEDAGFLPRDHQLRVLYDLAHNNAKFEEYAGRRVLVHRKGATRAFGPGAPDVPPAFRTVGQPVLVPGDMGRYSFVLAGTPGAMTRTFGSSCHGAGRQMSRHKAKKAARKRNLIAELEAQGILVRAASRATVDEEMPEAYKDVASVVDVVHGAGIGKKVARLRPLIVVKG
>NC_015387.1|WP_013703011.1|197374_197995_+|HAD-family-phosphatase
MELRGVLFDWGGVFTVGTFDGRVVRTLAQHFGLEEARVAEAYFARVAHLEVGAWSLAEFWEALAEALGVEAPYASFELLFLSCVAPRHEMYALLAAWPPELRVGLLSNNYPVISQYLRSGPHFDRFDAVVFSNEEGVKKPDPRAFQLALERLELPAEAVLFVDDNAENLEAARQLGFRTHHFQDPEGFRAALKAEGVTLPAAPQTP
>NC_015387.1|WP_013703012.1|197996_198341_+|DUF3208-domain-containing-protein
MRAVKLFQGYLWHPKDRGLEGRALLPECLEVPFAGGAARVWVLVDAVPPPFAFFEDGTPTATQAFYQVTLLTKTERAPAELKPLSEAVAARLEPLLNALPEGVGWLLLEDLREV
>NC_015387.1|WP_013703013.1|198383_198836_+|IS607-family-transposase
MDPLLLTAHQIRERYGLHRNTLYKWEQQDLLHPVRTPGGRRRYRREEIERLLSLGLEAPPAKPKPRTVLYARVSTRKQEAFLKNQIARLEAFARERGWTYEVIAEVASGVNENRRGLVKLLNRAKNGEVERVAVRLGPHPGGGPVCTSVH
>NC_015387.1|WP_013703014.1|198876_199911_+|M42-family-metallopeptidase
MALDYTLLKELTETPGIPGWEDRVRARVLEAVKPLVDEVRTDALGNVIAHKRGRGPRVMLAAHMDEIGFYVRHVDARGFLRLQPAGGFDARNLFARQVVVHAREGDLVGVLNPGGRPIHLSTPEERKKVPEIREFFVDLGLPADEVQARVRVGDPVTLRQETLDLGRVLTGKAMDDRASVFLLIEALKALAGKTPAYDVYAVFTTQEEVGLRGAVTSAYGVEPEIGIALDVTLAVDTPGAPEEEAVTRLGEGVGIKVMDGASISDRRLVTTFVDLAEKKKIPYQMEVLPLGGTDAGAIQRARAGVPAITLSIPTRYIHTVTETVHKADLEAGVNLLVAYLLGEA
>NC_015387.1|WP_041658151.1|199978_200188_-|hypothetical-protein
MWYVTLFFIGSLVVGYVLYVALSPRSVAVEGENVDLRFIGFVLALIILAAFTISAMLILGKIDEIAPPL

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Crispr_ID: NC_015387_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_2

274044-277499

TypeI

I-C,III-B

Consensus_repeat	Method
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	PILER-CR
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CRISPRCasFinder
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CRT

47 spacers

cas2,cas1,cas4,cas7b,cas8c,cas5,cas3,c2c10_CAS-V-U3

The CRISPR arrays of NC_015387_2

>merge|NC_015387|2|274044-277499|PILER-CR,CRISPRCasFinder,CRT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCAGGCGCCTACCACGGGCCGGTCCTCGTGGTCTGGGGCAGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACACGAGGCCGCGAGCCGCCTCCGCATGCAGCTCGAGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGGCAAAACCGGGATGGTAGCTACACCCTACCCACCGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTCATGAGGGAGGGGGAGAGTAGATGCGGTACGCGCTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGCGGGGGTCGCGCACCGGGCGGACGCGGGGGACCTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACATCGAGGGCACCGCGTACACGACCCGACCCATCCGGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTCGACCCGCAACGGCAACGCCCCGTCGTACGTGATGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACACCAGGACCTGCACCTCCCCCCGTGCGTACGCTTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGGTAACGCTGTAATGAACTTGGATCTTTACGCGAGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGCGTTAGGTTTGGTTTTGGCGGGGGTCCTCACGGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCGCTCTAGAATCGATACTGTAAACCTCGTCAATTGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCTGGATGACCGCGCGGCGCTCACCGCGTTGTGCGGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACAGGCGTGGGGGGGTGGGGCTTGCGCTGGTGTATCGCGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTTGAGGGCTTCCCACACGCTCATGCCTGGCCTCCCGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACATCATGCAGCACCCCGACTGGCGTAAGTACCTGGCGTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGTGCGGGATCGCCTCATGGCCCTCTCCGGGGAGCGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACATACCCAGTCTAAACTCACGTGACTTGACATACAGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGTGTGTTTGTGGGGGAATTCAATCTCCAAGGAGACGGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCCCGCCGCGTTTGCCACGCGGCCAAACGTCCTGGCGAGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGCGCTTGGACGGGCGGGGGCCTTGACGGGCAGGGGCGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACACGGGGTGCCCGCGCACGTGCCCAGCCTGAGCGAGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCTTGTACCGAGTCCAAGCGTTGATGCTCATGGCATGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCTGCCGGCTCAGCTGGGGGGCGGCGAAAAGAATTACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACAAAGCGCACGCCCGCACGCGCGGGTTTCGGAACCGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTTGTACCGAGTCCAAGCGTTGATGCTCATGGCATACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGGGAGCCTTGGCACCCGACCTCCTCCCCCACGAAGAGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACAGGGCCTGCGCGTCGTACGCCTCCAGCTTGGGTTTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGCGCTCAGTCCTTTGCATGCTATACCTCACCTCCACCCTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCCGGGGCCTTGACGGGCACGGGCGAGCCCCGAGCCCGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACACGGAGATCGCCCAACAGTACGGTTTGGAGTACGAGTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGTCCGCCAGGTGCGGCGCGACGCGGTCCAGGACCCACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTCGTGTTTGCACCGAGTATAACGTTTTGGGTCCTTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCTCAGGCGCGAGCACGGCAGGCCTCCAGCAGCTCGAGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGGTGAGTCCGCTACCGAGCGGGATGTGCTTGCCTACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACACGGCGCTGCTCGAGGTGCAGGACCGGTTGAACCAGTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACATCGAGCGGGGGTACCTGTCCCCCATCACGTACTACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTGCCCCTCGAGCACCATGCGCTGGTAGGCGCGCCACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTCCTTGCGGGGGCGCCGGTACCTCGAGGCGCTCTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTGCCATTGCCCGCTGGGGTGGCGTAGGTGCCGGTGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCGGGGTGTCAACGAGCAGGCGAAGCGGCTTTTTAAGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCCTTCCCGTACCTCGTCGGGTACGCCCGCTTGCCCCACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACGCCCAGCGGCGCAGCGTGGGCTCGCTCACCCCGAGGGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACCCCTAGGTTGCGGTCGGTAAAAAAGACGCTCAAGCGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACAGGGTTGGTGATCGTTTTGAGGTACGCACGTAAGCGGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAACTCGAGCCGCGCGAGCTCCCCCTCCACCACGTTCACGTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC

>NC_015387|2|2|274044-277499|PILER-CR
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CAGGCGCCTACCACGGGCCGGTCCTCGTGGTCTGGGGCA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGAGGCCGCGAGCCGCCTCCGCATGCAGCTCGAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGCAAAACCGGGATGGTAGCTACACCCTACCCACC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCATGAGGGAGGGGGAGAGTAGATGCGGTACGCGCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGGGGGTCGCGCACCGGGCGGACGCGGGGGACCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCGAGGGCACCGCGTACACGACCCGACCCATCCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGACCCGCAACGGCAACGCCCCGTCGTACGTGATG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACCAGGACCTGCACCTCCCCCCGTGCGTACGCTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGTAACGCTGTAATGAACTTGGATCTTTACGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGTTAGGTTTGGTTTTGGCGGGGGTCCTCACGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CGCTCTAGAATCGATACTGTAAACCTCGTCAATTG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTGGATGACCGCGCGGCGCTCACCGCGTTGTGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGCGTGGGGGGGTGGGGCTTGCGCTGGTGTATCGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTGAGGGCTTCCCACACGCTCATGCCTGGCCTCCC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCATGCAGCACCCCGACTGGCGTAAGTACCTGGCGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTGCGGGATCGCCTCATGGCCCTCTCCGGGGAGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATACCCAGTCTAAACTCACGTGACTTGACATACAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTGTGTTTGTGGGGGAATTCAATCTCCAAGGAGACGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCCGCCGCGTTTGCCACGCGGCCAAACGTCCTGGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGCTTGGACGGGCGGGGGCCTTGACGGGCAGGGGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGGGTGCCCGCGCACGTGCCCAGCCTGAGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTTGTACCGAGTCCAAGCGTTGATGCTCATGGCAT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTGCCGGCTCAGCTGGGGGGCGGCGAAAAGAATTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AAAGCGCACGCCCGCACGCGCGGGTTTCGGAACCG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTGTACCGAGTCCAAGCGTTGATGCTCATGGCATAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGGAGCCTTGGCACCCGACCTCCTCCCCCACGAAGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGGCCTGCGCGTCGTACGCCTCCAGCTTGGGTTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGCTCAGTCCTTTGCATGCTATACCTCACCTCCACCCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCGGGGCCTTGACGGGCACGGGCGAGCCCCGAGCCC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGAGATCGCCCAACAGTACGGTTTGGAGTACGAGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTCCGCCAGGTGCGGCGCGACGCGGTCCAGGACCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGTGTTTGCACCGAGTATAACGTTTTGGGTCCTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTCAGGCGCGAGCACGGCAGGCCTCCAGCAGCTCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGTGAGTCCGCTACCGAGCGGGATGTGCTTGCCTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGCGCTGCTCGAGGTGCAGGACCGGTTGAACCAGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCGAGCGGGGGTACCTGTCCCCCATCACGTACTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TGCCCCTCGAGCACCATGCGCTGGTAGGCGCGCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCCTTGCGGGGGCGCCGGTACCTCGAGGCGCTCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TGCCATTGCCCGCTGGGGTGGCGTAGGTGCCGGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CGGGGTGTCAACGAGCAGGCGAAGCGGCTTTTTAAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCTTCCCGTACCTCGTCGGGTACGCCCGCTTGCCCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCCCAGCGGCGCAGCGTGGGCTCGCTCACCCCGAGGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCCTAGGTTGCGGTCGGTAAAAAAGACGCTCAAGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGGTTGGTGATCGTTTTGAGGTACGCACGTAAGCG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGAGCCGCGCGAGCTCCCCCTCCACCACGTTCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC

>NC_015387|2|2|274044-277499|CRISPRCasFinder
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CAGGCGCCTACCACGGGCCGGTCCTCGTGGTCTGGGGCA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGAGGCCGCGAGCCGCCTCCGCATGCAGCTCGAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGCAAAACCGGGATGGTAGCTACACCCTACCCACC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCATGAGGGAGGGGGAGAGTAGATGCGGTACGCGCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGGGGGTCGCGCACCGGGCGGACGCGGGGGACCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCGAGGGCACCGCGTACACGACCCGACCCATCCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGACCCGCAACGGCAACGCCCCGTCGTACGTGATG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACCAGGACCTGCACCTCCCCCCGTGCGTACGCTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGTAACGCTGTAATGAACTTGGATCTTTACGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGTTAGGTTTGGTTTTGGCGGGGGTCCTCACGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CGCTCTAGAATCGATACTGTAAACCTCGTCAATTG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTGGATGACCGCGCGGCGCTCACCGCGTTGTGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGCGTGGGGGGGTGGGGCTTGCGCTGGTGTATCGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTGAGGGCTTCCCACACGCTCATGCCTGGCCTCCC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCATGCAGCACCCCGACTGGCGTAAGTACCTGGCGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTGCGGGATCGCCTCATGGCCCTCTCCGGGGAGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATACCCAGTCTAAACTCACGTGACTTGACATACAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTGTGTTTGTGGGGGAATTCAATCTCCAAGGAGACGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCCGCCGCGTTTGCCACGCGGCCAAACGTCCTGGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGCTTGGACGGGCGGGGGCCTTGACGGGCAGGGGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGGGTGCCCGCGCACGTGCCCAGCCTGAGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTTGTACCGAGTCCAAGCGTTGATGCTCATGGCAT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTGCCGGCTCAGCTGGGGGGCGGCGAAAAGAATTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AAAGCGCACGCCCGCACGCGCGGGTTTCGGAACCG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTGTACCGAGTCCAAGCGTTGATGCTCATGGCATAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGGAGCCTTGGCACCCGACCTCCTCCCCCACGAAGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGGCCTGCGCGTCGTACGCCTCCAGCTTGGGTTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGCTCAGTCCTTTGCATGCTATACCTCACCTCCACCCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCGGGGCCTTGACGGGCACGGGCGAGCCCCGAGCCC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGAGATCGCCCAACAGTACGGTTTGGAGTACGAGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTCCGCCAGGTGCGGCGCGACGCGGTCCAGGACCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGTGTTTGCACCGAGTATAACGTTTTGGGTCCTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTCAGGCGCGAGCACGGCAGGCCTCCAGCAGCTCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGTGAGTCCGCTACCGAGCGGGATGTGCTTGCCTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGCGCTGCTCGAGGTGCAGGACCGGTTGAACCAGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCGAGCGGGGGTACCTGTCCCCCATCACGTACTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TGCCCCTCGAGCACCATGCGCTGGTAGGCGCGCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCCTTGCGGGGGCGCCGGTACCTCGAGGCGCTCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TGCCATTGCCCGCTGGGGTGGCGTAGGTGCCGGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CGGGGTGTCAACGAGCAGGCGAAGCGGCTTTTTAAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCTTCCCGTACCTCGTCGGGTACGCCCGCTTGCCCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCCCAGCGGCGCAGCGTGGGCTCGCTCACCCCGAGGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCCTAGGTTGCGGTCGGTAAAAAAGACGCTCAAGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGGTTGGTGATCGTTTTGAGGTACGCACGTAAGCG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGAGCCGCGCGAGCTCCCCCTCCACCACGTTCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC

>NC_015387|2|1|274044-277499|CRT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CAGGCGCCTACCACGGGCCGGTCCTCGTGGTCTGGGGCA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGAGGCCGCGAGCCGCCTCCGCATGCAGCTCGAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGCAAAACCGGGATGGTAGCTACACCCTACCCACC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCATGAGGGAGGGGGAGAGTAGATGCGGTACGCGCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGGGGGTCGCGCACCGGGCGGACGCGGGGGACCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCGAGGGCACCGCGTACACGACCCGACCCATCCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGACCCGCAACGGCAACGCCCCGTCGTACGTGATG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACCAGGACCTGCACCTCCCCCCGTGCGTACGCTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGTAACGCTGTAATGAACTTGGATCTTTACGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGTTAGGTTTGGTTTTGGCGGGGGTCCTCACGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CGCTCTAGAATCGATACTGTAAACCTCGTCAATTG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTGGATGACCGCGCGGCGCTCACCGCGTTGTGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGCGTGGGGGGGTGGGGCTTGCGCTGGTGTATCGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTGAGGGCTTCCCACACGCTCATGCCTGGCCTCCC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCATGCAGCACCCCGACTGGCGTAAGTACCTGGCGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTGCGGGATCGCCTCATGGCCCTCTCCGGGGAGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATACCCAGTCTAAACTCACGTGACTTGACATACAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTGTGTTTGTGGGGGAATTCAATCTCCAAGGAGACGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCCGCCGCGTTTGCCACGCGGCCAAACGTCCTGGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGCTTGGACGGGCGGGGGCCTTGACGGGCAGGGGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGGGTGCCCGCGCACGTGCCCAGCCTGAGCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTTGTACCGAGTCCAAGCGTTGATGCTCATGGCAT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTGCCGGCTCAGCTGGGGGGCGGCGAAAAGAATTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AAAGCGCACGCCCGCACGCGCGGGTTTCGGAACCG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTGTACCGAGTCCAAGCGTTGATGCTCATGGCATAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGGAGCCTTGGCACCCGACCTCCTCCCCCACGAAGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGGCCTGCGCGTCGTACGCCTCCAGCTTGGGTTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCGCTCAGTCCTTTGCATGCTATACCTCACCTCCACCCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCGGGGCCTTGACGGGCACGGGCGAGCCCCGAGCCC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGAGATCGCCCAACAGTACGGTTTGGAGTACGAGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GTCCGCCAGGTGCGGCGCGACGCGGTCCAGGACCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGTGTTTGCACCGAGTATAACGTTTTGGGTCCTT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CTCAGGCGCGAGCACGGCAGGCCTCCAGCAGCTCGA
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GGTGAGTCCGCTACCGAGCGGGATGTGCTTGCCTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ACGGCGCTGCTCGAGGTGCAGGACCGGTTGAACCAGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	ATCGAGCGGGGGTACCTGTCCCCCATCACGTACTAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TGCCCCTCGAGCACCATGCGCTGGTAGGCGCGCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCCTTGCGGGGGCGCCGGTACCTCGAGGCGCTCT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TGCCATTGCCCGCTGGGGTGGCGTAGGTGCCGGT
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CGGGGTGTCAACGAGCAGGCGAAGCGGCTTTTTAAG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCTTCCCGTACCTCGTCGGGTACGCCCGCTTGCCCCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	GCCCAGCGGCGCAGCGTGGGCTCGCTCACCCCGAGGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TTCACGCCGTGCGCGTCCTGCACGAGAAGCACGCGG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	CCCTAGGTTGCGGTCGGTAAAAAAGACGCTCAAGC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	AGGGTTGGTGATCGTTTTGAGGTACGCACGTAAGCG
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC	TCGAGCCGCGCGAGCTCCCCCTCCACCACGTTCAC
GTTGCACCGGCCCTTCGGGGCCGGTGAGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013703093.1\|271090_271960_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015387.1\|WP_013703098.1\|279726_280644_+\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NC_015387.1\|WP_013703101.1\|282427_282826_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013703099.1\|280725_281121_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NC_015387.1\|WP_083804404.1\|279082_279400_+\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|224629
NC_015387.1\|WP_013703092.1\|269286_271098_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|187887
NC_015387.1\|WP_052297189.1\|283776_284553_-\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|238380
NC_015387.1\|WP_013703097.1\|277668_277929_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_041657758.1\|278514_279063_+\|transposase	c2c10_CAS-V-U3	-	gnl\|CDD\|284650
NC_015387.1\|WP_013703103.1\|283423_283777_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|376737
NC_015387.1\|WP_013703100.1\|281121_282363_+\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	unknown	unknown	gnl\|CDD\|223362
NC_015387.1\|WP_013703096.1\|273563_273863_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015387.1\|WP_013703087.1\|261798_263037_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NC_015387.1\|WP_013703089.1\|264941_266246_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225139
NC_015387.1\|WP_013703088.1\|263049_264846_+\|menaquinone-biosynthesis-decarboxylase	unknown	unknown	gnl\|CDD\|163413
NC_015387.1\|WP_013703091.1\|268604_269294_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NC_015387.1\|WP_013703090.1\|266457_268593_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_015387.1\|WP_013703095.1\|272537_273560_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_015387.1\|WP_013703102.1\|282938_283427_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|238269
NC_015387.1\|WP_013703094.1\|271962_272541_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013703093.1\|271090_271960_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.45936e-133
NC_015387.1\|WP_013703098.1\|279726_280644_+\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	2.49487e-156
NC_015387.1\|WP_013703099.1\|280725_281121_+\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	2.24872e-40
NC_015387.1\|WP_083804404.1\|279082_279400_+\|restriction-endonuclease	gnl\|CDD\|224629	COG1715, Mrr, Restriction endonuclease [Defense mechanisms].	4.19661e-44
NC_015387.1\|WP_013703092.1\|269286_271098_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	2.854e-99
NC_015387.1\|WP_052297189.1\|283776_284553_-\|dihydropteroate-synthase	gnl\|CDD\|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	1.45252e-122
NC_015387.1\|WP_013703090.1\|266457_268593_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	6.3951e-55
NC_015387.1\|WP_041657758.1\|278514_279063_+\|transposase	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	6.03504e-17
NC_015387.1\|WP_013703100.1\|281121_282363_+\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	gnl\|CDD\|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	1.18785e-139
NC_015387.1\|WP_013703096.1\|273563_273863_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.30664e-23
NC_015387.1\|WP_013703087.1\|261798_263037_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.63934e-64
NC_015387.1\|WP_013703089.1\|264941_266246_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	1.77938e-121
NC_015387.1\|WP_013703088.1\|263049_264846_+\|menaquinone-biosynthesis-decarboxylase	gnl\|CDD\|163413	TIGR03701, mena_SCO4490, menaquinone biosynthesis decarboxylase, SCO4490 family. Members of this protein family are putative decarboxylases involved in a late stage of the alternative pathway for menaquinone, via futalosine, as in Streptomyces coelicolor and Helicobacter pylori. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
NC_015387.1\|WP_013703091.1\|268604_269294_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	4.44897e-79
NC_015387.1\|WP_013703103.1\|283423_283777_-\|dihydroneopterin-aldolase	gnl\|CDD\|376737	pfam02152, FolB, Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.	5.85507e-40
NC_015387.1\|WP_013703095.1\|272537_273560_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	2.00353e-171
NC_015387.1\|WP_013703102.1\|282938_283427_+\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|238269	cd00483, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is HPPK which catalyzes pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin (HP). The functional enzyme is a monomer. Mammals lack many of the enzymes in the folate pathway including, HPPK.	1.26056e-63
NC_015387.1\|WP_013703094.1\|271962_272541_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	1.12266e-37

>NC_015387.1|WP_013703096.1|273563_273863_+|CRISPR-associated-endonuclease-Cas2
MKRLDVLVTYDVETTTLEGRSRLRRVAQVCKNFGQRVQFSVFELRVTEAQLEEFEAKLLDIIDPENDSLRIYVLHGGRERSLRQYGVDRYIDFDDPLVV
>NC_015387.1|WP_013703095.1|272537_273560_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MNRVLLNTLFVQTQGAYLHLDHEVLEVKVENEVRLRVPLHHLGNVAVFGQVLVSPFLIHKLVEDGKELVYYTRSGRFRGRLQGPVQGNVLLRRAQHKALDTPQMTLELARGFVLGKIRNARGVLLRARRDDPDLAPRVEAPLQELLHLQEAVQRAVTLDELRGVEGMAAVHYFTALAHLVRVPGINFSGRNRRPPRDPVNALLSFLYTLLMNDVASALEGVGLDPQVGYLHALRPGRLALALDLMEEFRPWFTDRLALSLINRKQVSTRDFDYRPGGAVMLNEEGRKKVIVAYQKRKQEEVSHPLFKEKIPVGLVWHVQARLLARRIREDLETYVAFTPR
>NC_015387.1|WP_013703094.1|271962_272541_+|CRISPR-associated-protein-Cas4
MEEPVPISAIQHYAYCPRQYALIHIEQIWEDNLYTLRGHRAHAQVHTPEGMAREGMRVEYGLPLWSDQLGLVGQADVVEFLEDTPYPVEHKVGERRARHADTLQLTAQGLCLEEMFSVPVRKGALYYRQSRRRREVTFTPALRAEVMEVLQAIRTLQAHPALPPPVNDARCKDCSLVAACLPQARDRLEGLT
>NC_015387.1|WP_013703093.1|271090_271960_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSELHLDPTKRHEFVLLFDVKDGNPNGDPDAGNMPRVDPETMQGIVTDVALKRKVRDYVTLVKQNADGYRIFIQSESALNALIEEAAQAIGTEKNSKRPNKDLQAEMLRRYYDIRMFGAVLTTGDYNAGQVRGPLQFTFARSLDPVLPLELTITRKARTTEERMESGETEMGKKPLVPYGLYRAHGFYNPFLAGGWVSRDDLALFWEALQHLFDFDRSASRGEMHVRGLCIFSHENPKGNAPAHKLFELIRINRKTGVEAPRCFNDYTVEIGLPPSGVTLTCLVDPRKG
>NC_015387.1|WP_013703092.1|269286_271098_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MFKALVELGKALEQQGKLPPPGYYYYKEPIRWRVRVFPDRFLLTPIDRNAARPFSGRTSGVQAHFLVDEAGYALGVDRTPKGSPEKRAKEKFAAFCALLEKFLSWPDLRDKDLAREVERLLEGLRAGWGRDQLESTEIFSKEWVEFVPEVGPLQGTPLFEHPEAVRFWVTELAERAAPRGGEVIGQCAVCGQHAVRLVGRIPLGVKLVGNAPLHSFNQSAFPSYYGGSSPENNAHIGLCLPCADTASRAFNYLSQSENHRKSLISDSNKRDALTNQIALFWTKSPSAIEIGTQNLNGGELNALISEVLSESFASKPITPKPTLPQLQQLLSLPWRPVDSHLNLDDYGFYLAVLSPNVGRIALRDWMAVSLTTLKETLRTFLSATCIVPPGGGPAEPRAIGELVRALESANPNHLRGLLRTAYLGDPPPAGLLQAAVVRFRNARVLENPRESWRLRALASLLKLTLFYGKKEVERMEKLNPSHKTPAYLSGRLLAVLEEAQKRAQGFNLKRTLVERFYGAASTAPAATFGMLLRTAAVAHLPKAGRLNLLVEEILGALDDAGGFPKTLTLKEQAEFALGFYHQRASFREKTKEENLSEAEVQHE
>NC_015387.1|WP_013703091.1|268604_269294_+|type-I-C-CRISPR-associated-protein-Cas5
MERVGRVSIRVWGEYALFSRPEFKVERVSYPVITPSAARGVLEAIFWKPEIRYQIRRIGVLKPGRQVAILRNEIASRQGRTPIIVEHDRQQRTSLVLKDVAYLIEAEIHLRSHATEPVFKYTDQFRRRVERGQYHHTPYLGTREFTAFFAPMNGEAPPALDLEIGTMLFDIAFVEDNKRKELSFKRPGKTKPVKGYAQPLFFEARVENGWLEVPQALYRELRRLEGEDV
>NC_015387.1|WP_013703090.1|266457_268593_+|CRISPR-associated-helicase/endonuclease-Cas3
MYAHTKGSRGAPHPLNDHLEAVATRAAAFAQPFGGEEIAYCLGLFHDLGKATQAFQNYLSDCEAGRKPAGKVVHAVWGAWLLGAWFNELELPALSLPVLGHHAGLKSPGEASSVYAAKAAAQELREVAKFLQAWSPELPSPRSPRLSGTRGELFIRMLFSALVDADRLDTEAHFDPEAAQLRKARPNLETLWRRFEANQQALLQKTSGTLVNRIRRTIYEAALQAASLPPGFFRLTAPTGGGKTRTGLAFALKHALEHGLRRVIIAIPYTSIIDQTASEYREILGEDAVLEHHSALEVPDEEEQDPRRVMLRLASENWDHPLIVTTTVQLFESLFSHTPSRVRKLHNLSRAVILIDEVQTLPLELLRPTLDVLRELVDRYGASVVFSTATQPAFELAERVPEFTGVQVREIVPDYPRHFAALRRVHYVYCETPMAWEGVAAEIRARPQVMVVLNTRKDALRLLDALEDDPDVFHLSTLLCPAHRRAVLAEIKKRLGSGMPVRLISTQVVEAGVDLDFPEVWRAVGPLDRIVQAAGRCNREGSPSPGRTVIFTPKDGRVPQGTYRSGLGEAQVLLERYGPEALHEPEIFREYFTRLFSTVDLDKKQIQKLREELNYPEVAARYRLIEQETVPVAVPYEEGPKRLAEFLKRPGRRTWQRLQPYLVNLYRYEVIKQRDCVRKVNENLNLYEWTCVYDAVRGIHEFFADPADLVV
>NC_015387.1|WP_013703089.1|264941_266246_+|class-I-SAM-dependent-methyltransferase
MGASTPHERLKKTAQHLIEQVLPRPRPLGVRFWDGSLLPPEVPREDTVILVLKRPEVLARLLEPPLDLALGEAYLEGDFDVEGNLEKALEIAESLTPRLNPLEWAGVLRDATSLKKGLKALGVAARLKGRAHSKERDRQAIQHHYDVSNRFYRLWLDQRMVYSCAYFPQGDEDLDQAQENKLELVLKKLRLQPGERLLDVGAGWGGLIVYAAERYGAQALGVTLSKRQVEHARAVIAENGLEDRVQIELRDYRDVRGPFDKAASIGMAEHVGREKLPEYFRTLYQALRPGGLLLHHVITRGPVPPRFSKTVASGEFMRRYVFPDGEILPLWTHLKAAEEAGFEVCDVEDLRPHYAKTLRHWVARLEARFAEAVREVGAARARLWRLYMSASAYQFAAGHLAIHQVLLAKPNAKGQAAVPPSRADLYIGGGYGGR
>NC_015387.1|WP_013703088.1|263049_264846_+|menaquinone-biosynthesis-decarboxylase
MFRNLHAYLTALEQRGELVRIQAPVSHELEITEIADRMVKSGGPALLFENIPEKDFPLVIGLFGTAQRTAFALGVEALEDLADKVHRLLELEPQTGLAGLMRMLPKLGALKGFFPRRVRRAPVQEVVLRGEAVDLTRLPVQKCWPKDGGPFITLPLVITKDPETGEVNVGMYRMQVLDRASTAMHWQLHKTGRLHFEKAKRLGKRLEVAVALGGDPILTYAATAPIPPVPGVNEFNLAGFLRGAGVELVRGVTVDLPVPAEAEFVLEGYVDPAEDPVVEGPFGDHTGFYTLEDLYPRFHVTALTHRRNAIYPSTIVGRPVMEDAYLIEASERLFLPPARMILPELVDYHMPSAGVAHNWVNVAIAKRYPGQAYKVAHGLLGLGQMMFAKVIVVVDAEVPVKPGLPALTHALTHALPGRDTLLTRGPIDVLDHAARAMGFGGKLIIDGTRKLPEEGGEVPFAPQTHAELPPHPGVVAQHQWPGIWAVTLEKCHPHQARDLAQALSQYPQSVGIRLLLLTDADTDAANLEEVLWAVLNNIDPERDAWVLAGAGGPILALDGTRKLPEEGFARPWPEKIVMDPEVKRRVAARWAELGLPEG
>NC_015387.1|WP_013703087.1|261798_263037_+|sodium:proton-antiporter
MGPFEALAVLLTLTAAFAYLNERWVRLPTPVGVMLGAMLTSLGLVLLGGPTVRAWAAPLLARLEFSDLLLQGLLSFLLFAGALHVNLEDLLRRKWAILTLATLSVLTSTFLVGTLIHAALGWVGLELPYGYALLFGALISPTDPIAVLGILRKAGVPKPLEALITGESLFNDGVGIVVFRVLLGLALANGASETSLAEAGLLFLEEAGGGALLGLGIGLAAYAALRSVDRSTVEVLITLALVTGGYALAQYLHTSGPIAMVVAGLLIGNHGRLFAMSARTREHLDTFWEVTDEILNALLFVLIGLEVLILPYDPAYLAATLIAIPLVLLARLLSVGIPLGLLRLVRPLAPYTVRLMTWGGLRGGISVALALLVPPGPERDLILGMTYGVVVFSILVQGLTIGRVARYAARTP
>NC_015387.1|WP_013703097.1|277668_277929_-|hypothetical-protein
MGAVKQLTVPDDVFEGLEKLRRSMRTSRIEALRWLIRRELAFRELDRLWQEQSERNADLSEEEAMRIALEAVQEVRRASRSKGRKR
>NC_015387.1|WP_041657758.1|278514_279063_+|transposase
MRPHLLSHFVQTLTVRCTLKPTLEQAEALEATAKRFAEGCNHVLRVAKRTGTFRRFALHRLVYRDLRAMGLSANLAVQAIARVVRRKGQRAKHYQATSCDYDRPRHTSRTCSRCGHTSKASRRSQARFRCEACGFQHNADWVASVNIARRALAQGAGSAGPGHGQLALMLGHRLERLHLPAS
>NC_015387.1|WP_083804404.1|279082_279400_+|restriction-endonuclease
MTNEDKLGLDVIYIQAKQWSNPVGCPEVRKFVGALHGKKARKGVFITTSSFTKEAHDFVKHLDPKVVLIDGETLARLMIEHNVGVTVKSVYELKAVDRDFFEEPS
>NC_015387.1|WP_013703098.1|279726_280644_+|hydroxymethylbilane-synthase
MRVIVVGTRGSALALTQTRWVVERLKEQWPEAEFKIKTIQTRGDRGAPPTDRDIFVKELEEALLRGEIDIAVHSLKDLPTEQPEGLVIASIPKRVDPRDVFIGRNGIRRLEDLPEGAVVGTSSVRRKAQLLAYRPDLVVRELRGNVDTRLSALGSGEFDGIILAAAGLLRLDLRNRIDAFIDPKIMLPAPGQGALALEVREGDDIADELAYSIHHHPTDDRTTAERSFLHHLGAGCLAPVGALAHVEEDGTLRLEGVVVAPDGSSMIHGEIEGDAEEAWELGAELARDILEQGGKRILEGLRLEQ
>NC_015387.1|WP_013703099.1|280725_281121_+|transcriptional-repressor
MAMKRLTRQRKAVLEVVQRARNHPDAAWIYQEVRKLVPTISLGTVYRTLDALVEEGYLVPISRGGEATRYDANRKPHYHLICTSCGEIVDLEVELPELVGAARAAYPEHEIRAAHVEFEGVCAACRDRLAS
>NC_015387.1|WP_013703100.1|281121_282363_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase
MLEWLNALQLQGVRPGLGRIRALLARLGHPERAFPAVVVGGTNGKGSVTRALGGILEAAGYRVGVYTSPHLVRFNERIRVGGEEIQDAELAALLEEVRPHAEAVGASYFEVATVLALVHFARRGVDWAVLEVGMGGRFDATNAVDPVLSVITNVGLDHQRWLGATLAQIAREKAGILRPGRSALTAARGEGLRVLREEAGRVGARLLVLGEAFALEGVALGPEGVAFTLAYEGRHRLRAPVLGAHQAENLALAAVAARRLGVGWAAVRSGLERFMHPGRMEYLPERRLLLDGAHNPDGARALGRALEAHFSGWPRTLVLALSEDKDPRAFAAAFRECFERVVVTRYAAPRAMDPAALHAHFPGAEVVEESAKALERALAVTPPEGLVVVAGSLYLVGEVKRYLAGLEPEVRWQ
>NC_015387.1|WP_013703101.1|282427_282826_-|hypothetical-protein
MDLVGAIIAGLIGTAVMTILMYMAPAMGLPKMDVMGMLGTMFTETPSSARGIGAVMHFLMGAVFTLVYAGLWSAELGNPTAGWGILYGLVHGVIAILATPMMMRMHPRPPRCAPAPPQPQANSSGTPSTAWS
>NC_015387.1|WP_013703102.1|282938_283427_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MTRTAYVALGSNLGDRAGYLLAALSALGRTENIRLARLSRVYETAPVGPSGQGPYLNLVAEIETRLEPQPLLQTLLGIERRLGRVRRERWGPRTIDLDLLLYADVVLDAEALTLPHPRLHERAFVLAPLCDLIPDAVHPRLGRTYRALLEAVGRVGVRVWRP
>NC_015387.1|WP_013703103.1|283423_283777_-|dihydroneopterin-aldolase
MGRIVMQGLEFYGRHGVKPEEGTLGARFVVDVELEVPFEGRGDRIEETVDYAAVYATVAEVVTGERFYLIEALADRLAGEILARFARAEAVTVRVHKPHAPIPGVFRDVYAETHRAR
>NC_015387.1|WP_052297189.1|283776_284553_-|dihydropteroate-synthase
MGVLNVTPDSFSDGGRYLTVEAALLQARRMIAEGADLIDLGGESTRPGAQPVPVEEEKRRVLPLLEALLELGVPISVDTRKPEVAQAALELGAHLLNDVTGLRDARMLELAARYRVPVVIMHMPVPDPQTMMQHAHYDDVVAEVKAFLARQAARAIEAGVPQVVLDPGIGFGKRLEHNLELIRRLDELAALGHPVLLGASRKRMIGELTGVEAPAERVLGTVAAHLYGAARGAHILRVHDVRAHREALAVWEALEGGR

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Crispr_ID: NC_015387_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_3

522862-522953

Orphan

Consensus_repeat	Method
CCGGGGGAGGCGATCCCGGTGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015387_3

>merge|NC_015387|3|522862-522953|CRISPRCasFinder
CCGGGGGAGGCGATCCCGGTGGACGGCCGGGTCCTCGAGGGGCGCTCCGGTGTGAACGAGAGCCTGGTCACGGGGGAGGCGATCCCGGTGGA

>NC_015387|3|3|522862-522953|CRISPRCasFinder
CCGGGGGAGGCGATCCCGGTGGA	CGGCCGGGTCCTCGAGGGGCGCTCCGGTGTGAACGAGAGCCTGGTC
ACGGGGGAGGCGATCCCGGTGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013703350.1\|520031_520730_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_015387.1\|WP_169311725.1\|515150_515294_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234815
NC_015387.1\|WP_041657787.1\|529298_530315_-\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NC_015387.1\|WP_013703168.1\|513959_515060_-\|transposase	unknown	unknown	gnl\|CDD\|379252
NC_015387.1\|WP_013703360.1\|530391_531291_+\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NC_015387.1\|WP_013703346.1\|516470_517550_-\|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|259910
NC_015387.1\|WP_013703361.1\|531366_532248_+\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NC_015387.1\|WP_013703355.1\|525213_526503_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_015387.1\|WP_013703352.1\|521515_521923_+\|heavy-metal-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133398
NC_015387.1\|WP_013703362.1\|532202_532607_-\|HEPN-domain-containing-protein	unknown	unknown	gnl\|CDD\|368314
NC_015387.1\|WP_041657785.1\|518418_519498_+\|peptide-chain-release-factor-1	unknown	unknown	gnl\|CDD\|234801
NC_015387.1\|WP_013703347.1\|517546_518224_-\|metal-dependent-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224240
NC_015387.1\|WP_052297147.1\|524564_525026_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_148230449.1\|515304_516471_-\|metal-transporter	unknown	unknown	gnl\|CDD\|223505
NC_015387.1\|WP_013703356.1\|526506_527163_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015387.1\|WP_041657786.1\|528260_529265_-\|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	unknown	unknown	gnl\|CDD\|234893
NC_015387.1\|WP_013703357.1\|527230_528250_-\|tRNA-dihydrouridine(20/20a)-synthase-DusA	unknown	unknown	gnl\|CDD\|236991
NC_015387.1\|WP_013703363.1\|532611_532953_-\|DUF427-domain-containing-protein	unknown	unknown	gnl\|CDD\|377265
NC_015387.1\|WP_013703349.1\|519484_519964_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239217
NC_015387.1\|WP_148230450.1\|520763_521456_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181298

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013703350.1\|520031_520730_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	6.71983e-18
NC_015387.1\|WP_169311725.1\|515150_515294_-\|hypothetical-protein	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	2.96227e-16
NC_015387.1\|WP_041657787.1\|529298_530315_-\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	2.01601e-104
NC_015387.1\|WP_013703168.1\|513959_515060_-\|transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.13877e-05
NC_015387.1\|WP_013703360.1\|530391_531291_+\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	1.93827e-145
NC_015387.1\|WP_013703346.1\|516470_517550_-\|multicopper-oxidase-domain-containing-protein	gnl\|CDD\|259910	cd11024, CuRO_1_2DMCO_NIR_like, The cupredoxin domain 1 of a two-domain laccase related to nitrite reductase. The two-domain laccase (small laccase) in this family differs significantly from all laccases. It resembles the two domain nitrite reductase in both sequence and structure. It consists of two cupredoxin domains and forms trimers and hence resembles the quaternary structure of nitrite reductases more than that of large laccases. There are three trinuclear copper clusters in the enzyme localized between domains 1 and 2 of each pair of neighbor chains. Three copper ions of type 1 lie close to one another near the surface of the central part of the trimer, and, effectively, a trimeric substrate binding site is formed in their vicinity. Laccase is a blue multi-copper enzyme that catalyzes the oxidation of a variety of organic substrates coupled to the reduction of molecular oxygen to water. It displays broad substrate specificity, catalyzing the oxidation of a wide variety of aromatic, notably phenolic, and inorganic substances. Laccase has been implicated in a wide spectrum of biological activities.	6.40528e-72
NC_015387.1\|WP_013703361.1\|531366_532248_+\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	5.60659e-36
NC_015387.1\|WP_013703355.1\|525213_526503_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.74118e-47
NC_015387.1\|WP_013703352.1\|521515_521923_+\|heavy-metal-responsive-transcriptional-regulator	gnl\|CDD\|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.38197e-49
NC_015387.1\|WP_013703362.1\|532202_532607_-\|HEPN-domain-containing-protein	gnl\|CDD\|368314	pfam05168, HEPN, HEPN domain.	1.49512e-08
NC_015387.1\|WP_041657785.1\|518418_519498_+\|peptide-chain-release-factor-1	gnl\|CDD\|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NC_015387.1\|WP_013703347.1\|517546_518224_-\|metal-dependent-transcriptional-regulator	gnl\|CDD\|224240	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription].	7.37588e-51
NC_015387.1\|WP_148230449.1\|515304_516471_-\|metal-transporter	gnl\|CDD\|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	7.25614e-13
NC_015387.1\|WP_013703356.1\|526506_527163_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.78877e-71
NC_015387.1\|WP_041657786.1\|528260_529265_-\|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	gnl\|CDD\|234893	PRK01045, ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed.	3.39488e-124
NC_015387.1\|WP_013703357.1\|527230_528250_-\|tRNA-dihydrouridine(20/20a)-synthase-DusA	gnl\|CDD\|236991	PRK11815, PRK11815, tRNA dihydrouridine(20/20a) synthase DusA.	0
NC_015387.1\|WP_013703363.1\|532611_532953_-\|DUF427-domain-containing-protein	gnl\|CDD\|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	5.20672e-49
NC_015387.1\|WP_013703349.1\|519484_519964_+\|NUDIX-hydrolase	gnl\|CDD\|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	3.81347e-24
NC_015387.1\|WP_148230450.1\|520763_521456_+\|SDR-family-oxidoreductase	gnl\|CDD\|181298	PRK08219, PRK08219, SDR family oxidoreductase.	3.01369e-74

>NC_015387.1|WP_013703352.1|521515_521923_+|heavy-metal-responsive-transcriptional-regulator
MRREPRIGEVARALGLSPKAIRYYEAIGLLPPPRRTPAGYRVYGEADLERLRFVQKAKASGLTLSEIREVLTLWEAGTPPCDRVRALLDRKIAEVEAEIRALLAFRAELRRLRRAASRRGREQAVVCAILERTAG
>NC_015387.1|WP_148230450.1|520763_521456_+|SDR-family-oxidoreductase
MITGASSGIGRAIALELAQRGAHLHLVGRDPTRLEQVAEAARAAGGTARVYRADLAEDAALEALARDLAALERVDVLVHSAGVVALGPVATAPVEKLDWQYRVNLRAPFALTQALLPALERARGQVVFINSGAGLRANAGWSQYAATKHGLKALADALRAEVAPRGVRVISVYPGRTATPMQAEVHRAEGRAYHPERFVQPEDVALEVLAALSLPARAVVTDLSIRPAVG
>NC_015387.1|WP_013703350.1|520031_520730_+|tetratricopeptide-repeat-protein
MEHTSVEDLMRAGRLEEAFARAMAGEAGPIEAIRAAMDLRELVWAKRYAEALRFLEMERRTLEPYLDVDRLGAGLEAFRAGGSVEAYLDDPLLGGEAWVLEGLRRVEAGDLAGARAAFEQAVALDPRHYRAVTNLANTYLEAGEVEEAIRLYRKAIKLNEAYPEAHESLAAAYRKQGKLHESVTHFKRAQRLRLRPRQGPRTGKEPARPGLFGGRWWVWIILIVAAYLLLNR
>NC_015387.1|WP_013703349.1|519484_519964_+|NUDIX-hydrolase
MDGLRRELLVASGILMDSRGRVLLVANDWGRRGRVRYTLPGGVVEPGETVVDAVVREVREETGLRVMQMEHLAYVVQVEDKRKRERTVVMTFKVRWDGLLNPRDPDGHIVEARFFDLEEVRERLSTHTPLSEPLLYYLETGSAGRFYAYTGWSTRGHRV
>NC_015387.1|WP_041657785.1|518418_519498_+|peptide-chain-release-factor-1
MLEKLKQLETEYQALEAQLGDPGVLADPKRYRELSRRYAELGEIVRVYREYTKTLDDLEQAQALLDDPELGEMARAEKETLEARRDELERELELLLLPKDPVDAKNAIVEIRAGTGGEEAALFAGDLYNMYVRYAERLGYTVEVLDSHPTDLGGFSKVVFQVNGSGAYGVFKYESGVHRVQRVPATETQGRIHTSTATVAVLPEAEEADFELDMSEIRIDVQRASGPGGQGVNTTDSAVRVVHLPTGIIVTCQDSRSQIKNREKALTILRSRLLEMKRAEEEAKLRRTRLAQIGTGERSEKIRTYNFPQSRVTDHRIHYTTHNLEGVLAGELEELTNALKKADQERMLEELNQEAHGRA
>NC_015387.1|WP_013703347.1|517546_518224_-|metal-dependent-transcriptional-regulator
MTKTQRPQLSEAQEDYLKQILLLSETEPTVTTQALAERLQVKPASVTGMLKKLAELGLVEYTAYRGVRLSEAGEKVALEILRHHRLLEAYLTEALGYSWDEVHDEAERLEHHISEALEARIAAFLGHPTHDPHGDPIPTADLSLPETPDLTPLTDLPPGRGGRLIRVTAQDKDTLNLLAHLHLIPGARVEVVERSANGLRVRVQGERFLLPLPLTKSLWIAEDEA
>NC_015387.1|WP_013703346.1|516470_517550_-|multicopper-oxidase-domain-containing-protein
MNRSRRALLKGSLLAGLGALGAQLLRPFALAHEGHAQAPGTHQTRHGGMTTVGEVDHEKNGFDPYAFLTHWETGEVSTLPSGQTLREFNIVAVDKEIEIAPGVYFPAWTYNGQVPGPTLRVTEGDRVRVHFHNAGSHPHTIHFHGIHPASMDGVPGTGPGMIYPGESFTYEFDAYPFGCHLYHCHAIPLKRHIHKGLYGAFIIDPDPERHPEYQAAARARLLGTPENQAWQEFVMVMNGFDTNFDEENEVYAVNTVAHAYMKRPIRIERDRPVRIYLINATEFDPINSFHLHANFFDYYDHGTTLTPTLKTVDTIMQCQGQRGILEFSFNGFEPGLYMFHAHQSEFAELGWMGNFEVIE
>NC_015387.1|WP_148230449.1|515304_516471_-|metal-transporter
MPERSPTHHTWLWAVLPFAILLGLLGLFLTTDPLKPLGVTAPPLEALTVERTVLDETGIRLKVRADGSEPLTIAQIQVDGAYWEFTQDPPGPLGRLQTAWITLPYPWVEGEAHFITFVTRTGMTFEHEIPVAVESPRWTPARVLAYALLGLYVGVVPVSLGLLFYPYLRTLRAHGLRFILALTMGLLAFLLVDTLEEGLELAEGAAAAFQATPLVWLAALLSFLALFAFGRRGGRAPEGLGLATYLAFGIGLHNLGEGLAIGAAFAAGEAALGAFLVVGFTLHNLTEGIGIAAPLTRHPVRLVHFVGLAALAGLPAVLGTWAGAFAFAPHWAALLLGIGAGAILQVIVEVGAYLARTTQGRWLSPASLAGFALGLAVMYTTAFLVNVG
>NC_015387.1|WP_169311725.1|515150_515294_-|hypothetical-protein
MNAEISLKRPFWFYLGPAFLVSVGYMDPGNWATSLEAGSRDSCKKVG
>NC_015387.1|WP_013703168.1|513959_515060_-|transposase
MTQAALSLLWTLLALLPSPHLQESLKALLLLLLHGHGKARPQHSQVKSPSALSRFLNRYPWPTRALIRLARKEAEKALDRARKKKGPKPRLLVVLDLVTLEKRGRFQALPLSFFHGKWGLHLVVLYLVYGDLRIPWAYRLWRGKGEKALSRLALSLLASLPPWMRRAFRIRVAADAAFGTTRFLFGVKRLGFEAVVGMRRDRRLREGGRLGDLRRQGSRVYLWGLSFPVWVAWYRYPLPQGGWEWRYVVATFPATPRTALTWGKRRFAIEHFFRAAKSEFSLGQFGQRTALGVHRFLVLSLLAYLLAHWVGMEGEGSWREARERAARVLLPELVVQVALRELYALGLWPPGGGGEGLCGICGRCKF
>NC_015387.1|WP_052297147.1|524564_525026_-|hypothetical-protein
MQSLVARVTVNDGRTLLLGSTRVEGDAPWLSLAAPGMLIQAEGYWRGRVFVAQQVQVLEPPDWAYYRGPAVLVRAGSSGDVEAWLSEGGLFAVQSAPEAGGLVRVVAFFDGVRLRFVPEALPPPPQGLARGWLELIGHFDGERVRWQEARPFP
>NC_015387.1|WP_013703355.1|525213_526503_-|HAMP-domain-containing-histidine-kinase
MNLRTRLFLGMTAAMLLAVGVQTGAGYLSFKRTLSDALTQDLERFAQDTARAIDLEGLRPAWRPDRVPELYGRWSNGRARLTKDGRVYLVYGGRFPEAAPDWARYTLSLTNGYRLEVALEALEVRRALGEYLRTSLWVLPLTLLLALFLAALLARYLMRPIRGLTRAMEQLSRQRFPEPVPPPPGNDELRHLAESFNRMTQALQAFIERERAFTRYASHELRTPLTTLSAQVEALELGLLPPERVIPTLKSTLERMERILSSLLALTRTAPPRLEPLSAWALVERTLAALPPPARARVRSTPPLAPLALLGEPHLVQQALGNLLDNALKYAPGPVDCTLDANTTEVTITVRDYGPGVAPEMLERITEPFFRAHRGTDGLGLGLALVQHIARSLGGRLELRRAEPGLEARLVLPRAKGTAREVEARRAEA
>NC_015387.1|WP_013703356.1|526506_527163_-|response-regulator-transcription-factor
MRILLVEDEPTVAEPLRALLTREGYAVTWAPDLEAAWRALTDGEPDLAILDVMLPEDENGGFVFAQQLREAGYQGPILFLTARDALEDRVAGLDLGGDDYLVKPFALRELLARVRALLRREAQTKQSRLVRGPLEVDLAARRVRYDGRSVVLTEKEFALLEHFALYPEKTFTVEELLERCFPGTTSGPRIVRVYVHRLRQKLAPQVIETVPGGYRLGV
>NC_015387.1|WP_013703357.1|527230_528250_-|tRNA-dihydrouridine(20/20a)-synthase-DusA
MPHAPPPNPHTLSIAPMMDWTDRHFRYLMRQVSRKVRLYTEMVVDRALIHGDRARLLAFHPEEHPLALQIGSSDPDLAFEAARIGVAWGYDEINLNVGCPSNRVQEGGFGACLMADPERVREITRAMREAAPVVTVKHRIGIDHLDEYRHLARFVETVAETGVTVFIVHARKAWLQGLSPKENRAVPPLRYGEVYRLKQDFPELTIVLNGGVRTLDAAMAHLEHTDGVMIGRAAYETPWAWAGADQQVFGLDRAPSRREVVMAMLPYIEARLMEGVPLRRIARHLLNLFKGAPGGRRFRRVLSEGLLDPTAGPELVQRALEAIPDAVLDERPGKAVAAR
>NC_015387.1|WP_041657786.1|528260_529265_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase
MVERVYLAKPRGFCAGVVMAIQAVEKAARELKDQGELVVYHSIVHNDVVVRRLREAYGVHFVEDLKEIEALRKERRLADTVVFSAHGIPPTVRRQAAEMGLWQIDATCPLVTKVHSEAKRYAREGYWILLIGDSADHQEVKGTMGEAPDRTILVAVHTHVGKDPRLADPRTVKVPDPDRVVVLTQTTLSVDDTLETIAILRERFPKLVVPSRDDLCYATKNRQDAVKRIAPHVDFFLVLTSNYSSNGMRLLELARNLVGRAERIDTAQDLRPEWFAGVRTVGITSAASTPDDLVQEVVAYFRAQNPNLEVIEEGEWEQIEFREPKRKAPEEVRV
>NC_015387.1|WP_041657787.1|529298_530315_-|DNA-protecting-protein-DprA
MDWLSLALTPGVGPARFMRAFQEGAASPERVRAVLGPRIAAAYAETLADGVAERARAQAAAHGARILGLWEADYPEALRHLTDPPLVLYVRGALPPYEQSVAIVGTRRASPWAKAWTRRTARALAEAGVAVISGLARGIDTEAHAGALEGGGLTVGVLGSGLDRIYPRENQALAERVTLVSELPFGEPPRPEYFPRRNRVVAALARAVLVVEAPPKSGALITAALALELGREVLAVPGRPTDPGAAGPNRLIQEGAGLVTNAAEVLEALNLAPTPALRPELTEAEARLYAALRAAGEALPDELAEELQLTAGEVLAGLAALELKGLAQALPGGRYAAV
>NC_015387.1|WP_013703360.1|530391_531291_+|GTPase-Era
MTNAKTYSGFVAIVGKPNVGKSTLLNTMLGVKVAPITPKPQTTRKTVRGIYTEGNRQIVFVDTPGLHKPADALGEYINEQVYEALADVNLILWLVDLRHPPTDEDRLVARALEPLVGRVPILLVGNKVDAAKYPDEALEAYRALLPQIEEVRTLSALDERDVANLRAEILALLPEGPFFYPDTFTRSDQPPEQWAAEIVREEAMKRLREEVPYAVAVKVETFEERPNGVVYIQAVLYVEREGHKAIVIGKQGRMLKEIGRAARKQLEVFLNRKVYLDLEVRVYPNWRKDPEALRELGYE
>NC_015387.1|WP_013703361.1|531366_532248_+|acyltransferase
MPWLLPKSITPEADEWLERWLGELTERLADPATDRNALVAEILSEVLYARPYEELKETAPLAALALDPRNVTFEAEYYAATDPEKFARVKPLLWLWKTLDLTPLGQSIHSGVRIRRALAPFIFKRVGKNPKFFQNVEFSVGYNLELGDDVVVHRHVLLDDIGGIVIGDGASISDYANIYSHTHHVLASPDVTLKQTIIGNGVRITYHATVLAGVRIGDDAMVGTGAVVTRDVPPHAIALGIPARPRRYKVRHDCPYCRAEAPHPSDEVPKLPDRKPNPDYPDFLPPGFGTREA
>NC_015387.1|WP_013703362.1|532202_532607_-|HEPN-domain-containing-protein
MPLELRHEAWRRAEEDLQAARLLLGHSPRASLSRAYYAMHWALVAYYLEAGRSFPHRKALLRTFSEEAEGTDLAAWARRVRQAERLRERADYDLSRATSRKTAREVVIWAQELIRALRSRQASRVPNPGGRKSG
>NC_015387.1|WP_013703363.1|532611_532953_-|DUF427-domain-containing-protein
MKRLRVEPAARRVTVRFNGTVVADSTHALVLHETGLPPVYYLPPRDVRMEYLTPTDHQTRCPYKGLARYWTVRVGDHTAENAAWSYPEPDQPDAQPIAGYLAFYPDRLEVTVA

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Crispr_ID: NC_015387_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_5

742571-742659

Orphan

Consensus_repeat	Method
AACCAGATCGCGGACCTCACGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015387_5

>merge|NC_015387|5|742571-742659|CRISPRCasFinder
AACCAGATCGTGAACCTCGCGCCGCTCGCGGGGCTCACGGAGCTGCGCGTGCTGGTTTTGGGGCAGAACCGGATCGCGGACCTCACGCC

>NC_015387|5|5|742571-742659|CRISPRCasFinder
AACCAGATCGTGAACCTCGCGCC	GCTCGCGGGGCTCACGGAGCTGCGCGTGCTGGTTTTGGGGCAG
AACCGGATCGCGGACCTCACGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013703565.1\|739150_740962_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NC_015387.1\|WP_013703563.1\|736238_737306_-\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273938
NC_015387.1\|WP_013703566.1\|740991_741402_+\|NADH-quinone-oxidoreductase-subunit-15	unknown	unknown	gnl\|CDD\|371564
NC_015387.1\|WP_013703557.1\|731009_731762_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl\|CDD\|223404
NC_015387.1\|WP_013703571.1\|745302_746748_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NC_015387.1\|WP_013703562.1\|735622_736228_-\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|238836
NC_015387.1\|WP_013703560.1\|733891_734995_+\|fructose-1,6-bisphosphatase	unknown	unknown	gnl\|CDD\|376679
NC_015387.1\|WP_013703576.1\|749850_750402_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013703564.1\|737324_739151_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|223097
NC_015387.1\|WP_013703570.1\|744391_745306_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_015387.1\|WP_013703574.1\|748040_748475_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NC_015387.1\|WP_013703568.1\|742958_743777_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|224790
NC_015387.1\|WP_013703577.1\|750405_750711_+\|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl\|CDD\|234845
NC_015387.1\|WP_013703558.1\|731811_733260_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|234660
NC_015387.1\|WP_013703569.1\|743894_744320_-\|disulfide-bond-formation-protein-B	unknown	unknown	gnl\|CDD\|179540
NC_015387.1\|WP_013703559.1\|733298_733721_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013703561.1\|734978_735608_-\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|224345
NC_015387.1\|WP_013703578.1\|750857_752054_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NC_015387.1\|WP_013703572.1\|746767_747568_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|376891
NC_015387.1\|WP_013703573.1\|747648_748041_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013703565.1\|739150_740962_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NC_015387.1\|WP_013703563.1\|736238_737306_-\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	4.88019e-65
NC_015387.1\|WP_013703557.1\|731009_731762_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl\|CDD\|223404	COG0327, COG0327, Uncharacterized conserved protein [Function unknown].	4.87561e-75
NC_015387.1\|WP_013703566.1\|740991_741402_+\|NADH-quinone-oxidoreductase-subunit-15	gnl\|CDD\|371564	pfam11497, NADH_Oxid_Nqo15, NADH-quinone oxidoreductase chain 15. This protein, Nqo15, is a part of respiratory complex 1 which is a complex that plays a central role in cellular energy production in both bacteria and mitochondria. Nqo15 has a similar fold to Frataxin, the mitochondrial iron chaperone. This protein may have a role in iron-sulphur cluster regeneration in the complex. This domain represents more than half the molecular mass of the entire complex.	7.09519e-75
NC_015387.1\|WP_013703571.1\|745302_746748_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NC_015387.1\|WP_013703562.1\|735622_736228_-\|deoxynucleoside-kinase	gnl\|CDD\|238836	cd01673, dNK, Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1.113), adenosine (EC 2.7.1.76), and thymidine (EC 2.7.1.21) kinases. They are key enzymes in the salvage of deoxyribonucleosides originating from extra- or intracellular breakdown of DNA.	1.20326e-62
NC_015387.1\|WP_013703560.1\|733891_734995_+\|fructose-1,6-bisphosphatase	gnl\|CDD\|376679	pfam01950, FBPase_3, Fructose-1,6-bisphosphatase. This is a family of bacterial and archaeal fructose-1,6-bisphosphatases (FBPases). FBPase catalyzes the hydrolysis of D-fructose-1,6-bisphosphate (FBP) to D-fructose-6-phosphate (F6P) and orthophosphate and is an essential regulatory enzyme in the glyconeogenic pathway.	0
NC_015387.1\|WP_013703564.1\|737324_739151_-\|arginine--tRNA-ligase	gnl\|CDD\|223097	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	1.41393e-174
NC_015387.1\|WP_013703570.1\|744391_745306_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	7.84584e-161
NC_015387.1\|WP_013703574.1\|748040_748475_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	3.51374e-92
NC_015387.1\|WP_013703568.1\|742958_743777_-\|cyclase-family-protein	gnl\|CDD\|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	2.57361e-68
NC_015387.1\|WP_013703558.1\|731811_733260_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl\|CDD\|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
NC_015387.1\|WP_013703577.1\|750405_750711_+\|4a-hydroxytetrahydrobiopterin-dehydratase	gnl\|CDD\|234845	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated.	1.76763e-31
NC_015387.1\|WP_013703569.1\|743894_744320_-\|disulfide-bond-formation-protein-B	gnl\|CDD\|179540	PRK03113, PRK03113, putative disulfide oxidoreductase; Provisional.	1.55866e-52
NC_015387.1\|WP_013703561.1\|734978_735608_-\|deoxynucleoside-kinase	gnl\|CDD\|224345	COG1428, COG1428, Deoxynucleoside kinases [Nucleotide transport and metabolism].	6.72582e-71
NC_015387.1\|WP_013703578.1\|750857_752054_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NC_015387.1\|WP_013703572.1\|746767_747568_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|376891	pfam02673, BacA, Bacitracin resistance protein BacA. Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteristic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.	1.24849e-59
NC_015387.1\|WP_013703573.1\|747648_748041_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.25461e-73

>NC_015387.1|WP_013703566.1|740991_741402_+|NADH-quinone-oxidoreductase-subunit-15
MSENHDKALYEAWVEVLDWLKAYAVERGVRFEWEADFPDYIYRMHRPYDLPTRVMTVSLSDERGEPFFLADVSPRHAKLKQISFRVPGGHLHWHAHYEEGRGLVLGGKIPLTKEKLYQLADRARHHVDERRVERVS
>NC_015387.1|WP_013703565.1|739150_740962_-|excinuclease-ABC-subunit-UvrC
MRPADLPPLPEAPGVYLWKAGDEVIYVGKAKRLKARVTSYFHAEGKPARIAQEASSLEFIVTRDEIEALLLEANLIKAHHPRYNVLLKDDKHYPFLKLTNEPFPILLVTRRVQDDGARYWGPFPDAGAVRRIKRLIDRVFPLRKNSGYPMKRRRFPCLNHAMGRCLAPCVGQADPAAYAAVVRQVEQVLDGRIDALIAQMEARMHQAARETNFELAAEIRDQIQALKAFFNADQQAYALELGDLDFLGFARAGGYAMVQLYQMRGGRILGRANRFVEGVNEAEDAEILEAFLREHYLEATPLPPVVLLPFHVEAEAPLAAFLSQRAGRKVALRVPQRGEKARLLEFAAKNARLGLEAELKRLERKGDHPALKALAEVLRLSHRPYRIEGFDISNLMGEAVVASIAVLEGGRPKKSEYRRMRIRNLAGRPNDYVAIAEAVYRRFTGSLADKLPVPDLLLIDGGLGQVRAAAQALERAGLSVPLVGLAKREETLVLPSGERVTLPLTHPALQLLIHLRDETHRNGLRYNRKLRTQKHLKSLFDGIPGIGPRRKQVLLEHFSTLEELRQTPLETLARLPGMNRKAAQAVLEALKQHAPAQTGKIAP
>NC_015387.1|WP_013703564.1|737324_739151_-|arginine--tRNA-ligase
MLDVKSQLRTSVLQALQALGVEDPPEVVVQETPPDKPGDYGTPIAFQLARALRKPPPAIAAQLAEHLPLPQGVARAFAVGGYLNFELEPAHLIRAAAAPLEPFPKRPGKVLVEHTSVNPNKELHVGHLRNICLGDAISRILRFAGREVEVLNYIDDTGRQVAESLFALEHYGLTYDGTQKYDHWVGAAYVRLHQELADPEAKARLEPRIQEVLHRLEAGELRDEVDKIVRAQLETMHRLGAEYDVLVWESDIVREGFLAKAMALLEQTPYVSRPTQGKYAGALVIDVSAFLPGLEDPYLVLIRSNGTATYTAKDIAFQFWKMGLFKGLKFRPYAQEPSGKTLYTSAPEGEAMPFGGAKETINVIDVRQSHPQAVVRASLEVEGRPDLAARAYHLAYETVLLEGKPLSGRKGHTVSVDEVLDEAVRRARAIIAEKNPEHPDPNRAAEVVGIGAVRFAMVKTEPKKQIDFRWEQALSFEGDSGPYVQYAHARADSILRKAAEAGLTDADADPTMATPYEVQLAKVLLRFPEAVQDAAEQKTPHILAQYLLDLAAAWNAYYNAKTPEGRPATPVLQAPEGLRGARLKLVRQLRDTLRTGLELLGITAPEVM
>NC_015387.1|WP_013703563.1|736238_737306_-|trypsin-like-peptidase-domain-containing-protein
MHASWHKRVLAFAAVVFYATISWAALTSPDELARVEVIRRAILAVVKIQGTPAFSEFAEGPVWGSGFFYSPNRVVTNFHVIDGLRNITVTLQDGRTFPAQVFAVDRGIDIALLTVLGTSAPATLTFGSAKDLVPGQTAIVIGSPFGQRNLVSVGVISGKGPFEFTAQIGNPDVGLEIAEVIYTDARVEPGNSGGPLLDGQGRVVGVVDAVLGGPSGIGGLGLAIPADLVAQSIQDLERYGVPQRGYLGATLIDLSQLDPLLLRLAGLSSDLGAMVDQIEPGSPADQAGLRGASRDRLGKLTTLGDVILAINGKPVRSRHDVIQEVARYRPGDTITLTIWRGNKKLEVTVTLIARR
>NC_015387.1|WP_013703562.1|735622_736228_-|deoxynucleoside-kinase
MYIAIEGPIGVGKTTLARHLADHLNAELLLEVVEENPFLPLFYQDPQRYAFKVQVFFLLSRYKQLLPLSQPSLFTGAVVADYLFDKDYIFASLNLKDAEWELYADLYAHLSPKLPAPDLTIYLRAPVPVLLERIHRRGRPFEREISPEYLTRLTEAYDRHFERYPHPLWVLDNTEINYAENPADREWVAREVLQRVGQANL
>NC_015387.1|WP_013703561.1|734978_735608_-|deoxynucleoside-kinase
MYIAIAGNIGSGKSTLTAMLAERYRLHPVYEAVEENPYLEDFYRDMRAWAFHSQVFFLARRLEQHLKEINGRKRVVQDRTIFEDAFIFAKNLHRQGYLSERDWRTYLALYEGIAPALRMPDRLVYIRASLPTLRARIAKRGRTYERAIPDAYLQALNELYEEWVANYTLSPVLIVPGDELDFVEDAGARQWVYDALEAGGLTPPLTTEP
>NC_015387.1|WP_013703560.1|733891_734995_+|fructose-1,6-bisphosphatase
MRLTLSMLKADIGAVGGHTAPSPEVLARVREVITEGQRAVFLDSLVFHCGDDIVVALTHTRDPGDPEVHALAWEAFQEGTRVAQAQGLYGAGQDLLKDAFSGNLVGLGPQVAELQFEERPNEPVVLLAADKTEPGAYNLPLYLAFADPMHSPGLLLSPGLQAGFRFRVMDVEATEAEHVIDLAAPERLYDLAILLRDPHRFVIESIWSRKYPDEQAVAVSTTRLRNIAGRYVGKDDPVAIVRVQKIFPATEELGPCFALAPFVAGDTRGSHHLPLMPVPANTPASSYFCMPMVMGLAVSIKNGRFTRPVDMFSDPVWEHVRRHVVEKAMEMRRQGFVEPAMLPYGELEYTGIRDRLERLLEEFTVRS
>NC_015387.1|WP_013703559.1|733298_733721_-|hypothetical-protein
MRGPVFLSILTVFATLTLANPDTARAHLTYVIELTEAREVALEQCPPLQPQALPAGARVVLQTCLEIPPQLAGFTRRFAHALEGRAGFSGTYQGAFANSERYAYQTPEGMLYLAYVIAGNRVGMTYFTLDAAQGPRPGFQ
>NC_015387.1|WP_013703558.1|731811_733260_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MTPVTTVAELFALYRAPGPPHPVKGVTHDSRRVQPGFVYVALRGQRCDGHRFIPDAVQRGAVAIVGEEPLEPGVPYLRVPDARRALSRLAAAFYGFPSTRLFVIGVTGTDGKTTTSCLVHHLLTRTGRGAGLISTVGLRYGEETRLLEGHFTTPEAPEVQAALAEMVRRGLTHAVLETSSHALAQHRVADVAYDLAVWTNLSPEHLDFHGSLEAYFQAKAALVNRAGFSILNAGCPYAMRLTHRPHTTYGVQAGAYRAVRVRESTDGLRFTLEAPGFTGEAFLPMIGRYNVENALAALAAAHRAGVPLEEALPALARFSGVPGRMQILQAHPIRAVVDFAHTPKALAKALTALRPTTPGRLIVVIGAAGERDPAKRAPLGRTAVTLADFAVFTEEDARSEDVHAILQEMERGAREAGGVRGTHYALKPDRRDAIRYALSLARPGDTVVFAGKGHERTLERADETLPWDEAEEVRKALGIAID
>NC_015387.1|WP_013703557.1|731009_731762_-|Nif3-like-dinuclear-metal-center-hexameric-protein
MRRDELVNWLDEYLDLPRYPDLSLNGLQVEGRPEVTRVGVAVDAAAPVFEKALEAGVDFLIVHHGLFWGKPLAVTGPHKRRLELLFSGGINLYAAHLPLDAHPEVGNNAVLARELGLVDLEPFGEFKGVKIGFKGRFPVPESLAQIADKLGQLTGMQCLVHQGGQDPVERVGIVSGGAAWTVVEAAREGLELFITGEPKHEVFHETFERGMNAIYAGHYDTEVFGVKALAQKLQETFGLEWVFLDHPTGL
>NC_015387.1|WP_013703568.1|742958_743777_-|cyclase-family-protein
MCAPTVMDAVAARMTRRGFLGLLGAAALAGTVARAEKRVAVKGFTKVQDLTHPLSPNFPMWPGFDPIRITPLVTVEQNGFYGNRVDFWEHSGTHMDAPAHFDADGPTAEQLPVERLFAPLAVIHIAERAAKDPDAQLTPDDILAWERRYDRLPAGAFVAMYSGWEQHASNAVRYRNMDASGTMHFPGFHPDAAAMLIEEREITGIGVDTLSLDFGASTDFKTHLTVLPAGKYGLENLAHLGELPPAGATIIVGAPKHQGASGGPVRAFAVWD
>NC_015387.1|WP_013703569.1|743894_744320_-|disulfide-bond-formation-protein-B
MSTDQRNTFLLAFAWLVAIVATSGSLYFSEVRRFLPCELCWYQRILMYPLVVILGIANWYGDFAVRRYVLPLAVIGGTISLTHYLTQKVEGFALFPCKPPVPCANEYVNYFGFVTIPFMALTAFVLITLAMLLIRTRPHNR
>NC_015387.1|WP_013703570.1|744391_745306_-|signal-recognition-particle-docking-protein-FtsY
MSWFQRLKEGLKKTSQAIAQAVPWGGDPEEVLEELEFALIAADVGVEATQEILEEVRQSGKKDLREAVKQSLVLQLEPDARRAKLRKLGFTPNAKKAVVEPKGRVVLMVGVNGVGKTTTIAKLGRYYRQHGRSVMFCAGDTFRAAGGAQLGLWGERLGIPVIQGPEGSDPGALAFDAAQARKARGIDLLFVDTAGRLHTKHNLMEELKKIKRAIDKADPGEPGEVWLVLDAVTGQNGLQQAKRFHEAVGLTGVIVTKLDGTAKGGVLVPIVRELGVPIRFIGVGEGPDDLQPFDAGEFVEALLG
>NC_015387.1|WP_013703571.1|745302_746748_-|glutamate--tRNA-ligase
MVTTRIAPSPTGDPHVGTAYIAIFNYVWARKNNGKFIVRIEDTDRNRYVEGAEARIQEMIRWLGLDYDEGTDIGGPNGPYRQSERTAIYQAHAAKLIETGAAYRCFCTPERLEALREEQKKRGLPLGYDGHCRHIPPEEAEARAKAGEPHVVRLKVPRPGQTVVKDELRGLVTYDHAEVPDVVLLKSDGFPTYHLANVVDDHLMGVTDVIRGEEWLVSTPIHVLLYQAFGWEAPLWYHMPLLRAPGGAKLSKRTGHTSVDWYRERGILAEALMNYLSLMGFSMPDGREIFTLQELIEAFSWERVSLGGPVFDYEKLKWMNGKYIREVLTLEDLTQRVKPFLERAGLEWGSDAYLQRVVAAMRIRFETLEEFVEKARYFFTEAYPFEEKALKKLKAGLEYVVELKERLGTLPEMDPELTEPLIRGYAAEKGAKPGAVMQPLRAALTGTLQSPGMFELLELLGKDRVLKRLERAIQTAEAEEA
>NC_015387.1|WP_013703572.1|746767_747568_-|undecaprenyl-diphosphate-phosphatase
MDLELLRAIVLGAIQGFTEFLPISSSGFLVLGNHFLFDLERLPLWVDLATNSGTFLAAAWVLRREITTVARGFARGLTASQARHEEGWRLMLWLFLATLPAALLGLVLAPVFEALNTPRVAAVGFFITGTLLLLVPPQGGPKRTADAMTFWDALLAGLAQALALVPGISRSGSTIAVLLGRGLSPSFAARFSFLMYTLVSLGAMLLGIQEGVGKVPWGPLFGAFLSAFVFGLLGMRLLFGVLEAGHFRYFTPLLWALALLTLLSAA
>NC_015387.1|WP_013703573.1|747648_748041_-|30S-ribosomal-protein-S9
MALEQYYGTGRRKTAVARVFLRPGDGKITVNKQDFQDYFRGIIKAVSALEPLRVTGLMGRFDLYITVKGGGKSGQIDAIKLGLARALLQYDADLRAKLKPAGLLTRDAREVERKKYGKHKARRAPQYSKR
>NC_015387.1|WP_013703574.1|748040_748475_-|50S-ribosomal-protein-L13
MFKTYVPKNIEPKWVLIDAEGKTLGRLASEIAKILRGKHRPEYTPNMLTGDFVVVINAEKVRLTGKKLTDKYYTRYSGYPGGLRKIPVGEMLKKHPERVLQHAVKGMLPKGPLGRRMLKRLKVYAGPTHPHAAQKPEKLELEVK
>NC_015387.1|WP_013703576.1|749850_750402_+|hypothetical-protein
MQRFSFPWTRVERGAGVLAVVAVGVLQGGLTWRLVRLAHAANLTFPELLNTVPEVRVPYALSWFAAFAVVYAVWAGAATRSRTVLEVGEAGLRFVRPGLPVLGLGAREVRLEPGAVTRLVLEDYGMRARFWLEAEGVRFAVPLEAGVAEGGSEGTRGGRDWERHPLVQLVVARTGGRLEVKRR
>NC_015387.1|WP_013703577.1|750405_750711_+|4a-hydroxytetrahydrobiopterin-dehydratase
MRRLTREEIAAGLEGLEGWALVADRVEKTFGFASYADGVAFALRVALLAERMDHHPDALTIGWKRVVVAYVTHSVGGVTERDLEAARQVETVYARMFAPNG
>NC_015387.1|WP_013703578.1|750857_752054_+|argininosuccinate-synthase
MKIVLAYSGGLDTSIILKWLKETYGAEVIAFTADIGQGEEVEEARQKALATGATKAYALDLKEEFVREFVFPMMRAAPLYEGYYLLGTSIARPLIAKHLVAIAEREGAEAISHGATGKGNDQVRFELTAYALKPGIRVIAPWREWHFKGRSEMIAYAQDHGIPVPVTTEKPYSMDANLLHVSYEGGILEDPWAEPPTDMFRMTTHPEDAPDEPEYVEITFEAGDPVAVNGQRMSPAELLAALNRIGGRHGVGRVDLVENRFVGMKSRGVYETPGGTLLYHARRAVESLTLDREALHLRDTLAPKYAELVYNGFWFAPEREALQAMMDRIAQSVTGTARLKLYKGNAYIVGRKAPQSLYDPELASFEAEEVYNQKDAEGFIKLNALRLRVRAQAKQEAP

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Crispr_ID: NC_015387_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_4

742043-742462

Orphan

Consensus_repeat	Method
AACCAGATCGCGGACCTCACGCC	CRISPRCasFinder

6 spacers

The CRISPR arrays of NC_015387_4

>merge|NC_015387|4|742043-742462|CRISPRCasFinder
AACCGGGTCGCGGACCTCGCGCCCCTCGCGGACCTCGGGCGCCTTGCGGTGCTGGTGGCTTGGCGCAACGCGGTGACGGACCTCCAGCCTTTAGCGAACCTGACGCGGATGCGGGTGTTGAGCTTGGCCTCGAACCGCGTCACGGACCTTACGCCCCTCGCGGAACTTGCGCAGCTGGACACGCTTTTCCTCTCTGAGAACCAGATCGCGGACCTCGCGCCCCTAGCGGGCCTTACCCAGTTGAAGGTGTTGAGTTTGGATTTTAACCGTATCACGCACCTCGATCCACTTGCGAGGCTCGTGGAACTCACGGAGCTGGGACTGGACGCCAACCAGATCGCGGACCTCACGCCCCTCGCAGGGCTTACGAATCTTCAGGTCCTCTCCGCCTCCGAGAACCGGATCGCGGACCTCACGCCG

>NC_015387|4|4|742043-742462|CRISPRCasFinder
AACCGGGTCGCGGACCTCGCGCC	CCTCGCGGACCTCGGGCGCCTTGCGGTGCTGGTGGCTTGGCGC
AACGCGGTGACGGACCTCCAGCC	TTTAGCGAACCTGACGCGGATGCGGGTGTTGAGCTTGGCCTCG
AACCGCGTCACGGACCTTACGCC	CCTCGCGGAACTTGCGCAGCTGGACACGCTTTTCCTCTCTGAG
AACCAGATCGCGGACCTCGCGCC	CCTAGCGGGCCTTACCCAGTTGAAGGTGTTGAGTTTGGATTTT
AACCGTATCACGCACCTCGATCC	ACTTGCGAGGCTCGTGGAACTCACGGAGCTGGGACTGGACGCC
AACCAGATCGCGGACCTCACGCC	CCTCGCAGGGCTTACGAATCTTCAGGTCCTCTCCGCCTCCGAG
AACCGGATCGCGGACCTCACGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013703565.1\|739150_740962_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NC_015387.1\|WP_013703563.1\|736238_737306_-\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273938
NC_015387.1\|WP_013703566.1\|740991_741402_+\|NADH-quinone-oxidoreductase-subunit-15	unknown	unknown	gnl\|CDD\|371564
NC_015387.1\|WP_013703557.1\|731009_731762_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl\|CDD\|223404
NC_015387.1\|WP_013703571.1\|745302_746748_-\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NC_015387.1\|WP_013703562.1\|735622_736228_-\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|238836
NC_015387.1\|WP_013703560.1\|733891_734995_+\|fructose-1,6-bisphosphatase	unknown	unknown	gnl\|CDD\|376679
NC_015387.1\|WP_013703576.1\|749850_750402_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013703564.1\|737324_739151_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|223097
NC_015387.1\|WP_013703570.1\|744391_745306_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_015387.1\|WP_013703574.1\|748040_748475_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NC_015387.1\|WP_013703568.1\|742958_743777_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|224790
NC_015387.1\|WP_013703577.1\|750405_750711_+\|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl\|CDD\|234845
NC_015387.1\|WP_013703558.1\|731811_733260_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|234660
NC_015387.1\|WP_013703569.1\|743894_744320_-\|disulfide-bond-formation-protein-B	unknown	unknown	gnl\|CDD\|179540
NC_015387.1\|WP_013703559.1\|733298_733721_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013703561.1\|734978_735608_-\|deoxynucleoside-kinase	unknown	unknown	gnl\|CDD\|224345
NC_015387.1\|WP_013703578.1\|750857_752054_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NC_015387.1\|WP_013703572.1\|746767_747568_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|376891
NC_015387.1\|WP_013703573.1\|747648_748041_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013703565.1\|739150_740962_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NC_015387.1\|WP_013703563.1\|736238_737306_-\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	4.88019e-65
NC_015387.1\|WP_013703557.1\|731009_731762_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl\|CDD\|223404	COG0327, COG0327, Uncharacterized conserved protein [Function unknown].	4.87561e-75
NC_015387.1\|WP_013703566.1\|740991_741402_+\|NADH-quinone-oxidoreductase-subunit-15	gnl\|CDD\|371564	pfam11497, NADH_Oxid_Nqo15, NADH-quinone oxidoreductase chain 15. This protein, Nqo15, is a part of respiratory complex 1 which is a complex that plays a central role in cellular energy production in both bacteria and mitochondria. Nqo15 has a similar fold to Frataxin, the mitochondrial iron chaperone. This protein may have a role in iron-sulphur cluster regeneration in the complex. This domain represents more than half the molecular mass of the entire complex.	7.09519e-75
NC_015387.1\|WP_013703571.1\|745302_746748_-\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NC_015387.1\|WP_013703562.1\|735622_736228_-\|deoxynucleoside-kinase	gnl\|CDD\|238836	cd01673, dNK, Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1.113), adenosine (EC 2.7.1.76), and thymidine (EC 2.7.1.21) kinases. They are key enzymes in the salvage of deoxyribonucleosides originating from extra- or intracellular breakdown of DNA.	1.20326e-62
NC_015387.1\|WP_013703560.1\|733891_734995_+\|fructose-1,6-bisphosphatase	gnl\|CDD\|376679	pfam01950, FBPase_3, Fructose-1,6-bisphosphatase. This is a family of bacterial and archaeal fructose-1,6-bisphosphatases (FBPases). FBPase catalyzes the hydrolysis of D-fructose-1,6-bisphosphate (FBP) to D-fructose-6-phosphate (F6P) and orthophosphate and is an essential regulatory enzyme in the glyconeogenic pathway.	0
NC_015387.1\|WP_013703564.1\|737324_739151_-\|arginine--tRNA-ligase	gnl\|CDD\|223097	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	1.41393e-174
NC_015387.1\|WP_013703570.1\|744391_745306_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	7.84584e-161
NC_015387.1\|WP_013703574.1\|748040_748475_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	3.51374e-92
NC_015387.1\|WP_013703568.1\|742958_743777_-\|cyclase-family-protein	gnl\|CDD\|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	2.57361e-68
NC_015387.1\|WP_013703558.1\|731811_733260_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl\|CDD\|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
NC_015387.1\|WP_013703577.1\|750405_750711_+\|4a-hydroxytetrahydrobiopterin-dehydratase	gnl\|CDD\|234845	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated.	1.76763e-31
NC_015387.1\|WP_013703569.1\|743894_744320_-\|disulfide-bond-formation-protein-B	gnl\|CDD\|179540	PRK03113, PRK03113, putative disulfide oxidoreductase; Provisional.	1.55866e-52
NC_015387.1\|WP_013703561.1\|734978_735608_-\|deoxynucleoside-kinase	gnl\|CDD\|224345	COG1428, COG1428, Deoxynucleoside kinases [Nucleotide transport and metabolism].	6.72582e-71
NC_015387.1\|WP_013703578.1\|750857_752054_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NC_015387.1\|WP_013703572.1\|746767_747568_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|376891	pfam02673, BacA, Bacitracin resistance protein BacA. Bacitracin resistance protein (BacA) is a putative undecaprenol kinase. BacA confers resistance to bacitracin, probably by phosphorylation of undecaprenol. More recent studies show that BacA has undecaprenyl pyrophosphate phosphatase activity. Undecaprenyl phosphate is a key lipid intermediate involved in the synthesis of various bacterial cell wall polymers. Bacitracin, a mixture of related cyclic polypeptide antibiotics, is used to treat surface tissue infections. Its primary mode of action is the inhibition of bacterial cell wall synthesis through sequestration of the essential carrier lipid undecaprenyl pyrophosphate, C55-PP, resulting in the loss of cell integrity and lysis. The characteristic phosphatase sequence-motif in this family is likely to be the PGxSRSGG, compared with the PSGH of the PAP family of phosphatases.	1.24849e-59
NC_015387.1\|WP_013703573.1\|747648_748041_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.25461e-73

>NC_015387.1|WP_013703566.1|740991_741402_+|NADH-quinone-oxidoreductase-subunit-15
MSENHDKALYEAWVEVLDWLKAYAVERGVRFEWEADFPDYIYRMHRPYDLPTRVMTVSLSDERGEPFFLADVSPRHAKLKQISFRVPGGHLHWHAHYEEGRGLVLGGKIPLTKEKLYQLADRARHHVDERRVERVS
>NC_015387.1|WP_013703565.1|739150_740962_-|excinuclease-ABC-subunit-UvrC
MRPADLPPLPEAPGVYLWKAGDEVIYVGKAKRLKARVTSYFHAEGKPARIAQEASSLEFIVTRDEIEALLLEANLIKAHHPRYNVLLKDDKHYPFLKLTNEPFPILLVTRRVQDDGARYWGPFPDAGAVRRIKRLIDRVFPLRKNSGYPMKRRRFPCLNHAMGRCLAPCVGQADPAAYAAVVRQVEQVLDGRIDALIAQMEARMHQAARETNFELAAEIRDQIQALKAFFNADQQAYALELGDLDFLGFARAGGYAMVQLYQMRGGRILGRANRFVEGVNEAEDAEILEAFLREHYLEATPLPPVVLLPFHVEAEAPLAAFLSQRAGRKVALRVPQRGEKARLLEFAAKNARLGLEAELKRLERKGDHPALKALAEVLRLSHRPYRIEGFDISNLMGEAVVASIAVLEGGRPKKSEYRRMRIRNLAGRPNDYVAIAEAVYRRFTGSLADKLPVPDLLLIDGGLGQVRAAAQALERAGLSVPLVGLAKREETLVLPSGERVTLPLTHPALQLLIHLRDETHRNGLRYNRKLRTQKHLKSLFDGIPGIGPRRKQVLLEHFSTLEELRQTPLETLARLPGMNRKAAQAVLEALKQHAPAQTGKIAP
>NC_015387.1|WP_013703564.1|737324_739151_-|arginine--tRNA-ligase
MLDVKSQLRTSVLQALQALGVEDPPEVVVQETPPDKPGDYGTPIAFQLARALRKPPPAIAAQLAEHLPLPQGVARAFAVGGYLNFELEPAHLIRAAAAPLEPFPKRPGKVLVEHTSVNPNKELHVGHLRNICLGDAISRILRFAGREVEVLNYIDDTGRQVAESLFALEHYGLTYDGTQKYDHWVGAAYVRLHQELADPEAKARLEPRIQEVLHRLEAGELRDEVDKIVRAQLETMHRLGAEYDVLVWESDIVREGFLAKAMALLEQTPYVSRPTQGKYAGALVIDVSAFLPGLEDPYLVLIRSNGTATYTAKDIAFQFWKMGLFKGLKFRPYAQEPSGKTLYTSAPEGEAMPFGGAKETINVIDVRQSHPQAVVRASLEVEGRPDLAARAYHLAYETVLLEGKPLSGRKGHTVSVDEVLDEAVRRARAIIAEKNPEHPDPNRAAEVVGIGAVRFAMVKTEPKKQIDFRWEQALSFEGDSGPYVQYAHARADSILRKAAEAGLTDADADPTMATPYEVQLAKVLLRFPEAVQDAAEQKTPHILAQYLLDLAAAWNAYYNAKTPEGRPATPVLQAPEGLRGARLKLVRQLRDTLRTGLELLGITAPEVM
>NC_015387.1|WP_013703563.1|736238_737306_-|trypsin-like-peptidase-domain-containing-protein
MHASWHKRVLAFAAVVFYATISWAALTSPDELARVEVIRRAILAVVKIQGTPAFSEFAEGPVWGSGFFYSPNRVVTNFHVIDGLRNITVTLQDGRTFPAQVFAVDRGIDIALLTVLGTSAPATLTFGSAKDLVPGQTAIVIGSPFGQRNLVSVGVISGKGPFEFTAQIGNPDVGLEIAEVIYTDARVEPGNSGGPLLDGQGRVVGVVDAVLGGPSGIGGLGLAIPADLVAQSIQDLERYGVPQRGYLGATLIDLSQLDPLLLRLAGLSSDLGAMVDQIEPGSPADQAGLRGASRDRLGKLTTLGDVILAINGKPVRSRHDVIQEVARYRPGDTITLTIWRGNKKLEVTVTLIARR
>NC_015387.1|WP_013703562.1|735622_736228_-|deoxynucleoside-kinase
MYIAIEGPIGVGKTTLARHLADHLNAELLLEVVEENPFLPLFYQDPQRYAFKVQVFFLLSRYKQLLPLSQPSLFTGAVVADYLFDKDYIFASLNLKDAEWELYADLYAHLSPKLPAPDLTIYLRAPVPVLLERIHRRGRPFEREISPEYLTRLTEAYDRHFERYPHPLWVLDNTEINYAENPADREWVAREVLQRVGQANL
>NC_015387.1|WP_013703561.1|734978_735608_-|deoxynucleoside-kinase
MYIAIAGNIGSGKSTLTAMLAERYRLHPVYEAVEENPYLEDFYRDMRAWAFHSQVFFLARRLEQHLKEINGRKRVVQDRTIFEDAFIFAKNLHRQGYLSERDWRTYLALYEGIAPALRMPDRLVYIRASLPTLRARIAKRGRTYERAIPDAYLQALNELYEEWVANYTLSPVLIVPGDELDFVEDAGARQWVYDALEAGGLTPPLTTEP
>NC_015387.1|WP_013703560.1|733891_734995_+|fructose-1,6-bisphosphatase
MRLTLSMLKADIGAVGGHTAPSPEVLARVREVITEGQRAVFLDSLVFHCGDDIVVALTHTRDPGDPEVHALAWEAFQEGTRVAQAQGLYGAGQDLLKDAFSGNLVGLGPQVAELQFEERPNEPVVLLAADKTEPGAYNLPLYLAFADPMHSPGLLLSPGLQAGFRFRVMDVEATEAEHVIDLAAPERLYDLAILLRDPHRFVIESIWSRKYPDEQAVAVSTTRLRNIAGRYVGKDDPVAIVRVQKIFPATEELGPCFALAPFVAGDTRGSHHLPLMPVPANTPASSYFCMPMVMGLAVSIKNGRFTRPVDMFSDPVWEHVRRHVVEKAMEMRRQGFVEPAMLPYGELEYTGIRDRLERLLEEFTVRS
>NC_015387.1|WP_013703559.1|733298_733721_-|hypothetical-protein
MRGPVFLSILTVFATLTLANPDTARAHLTYVIELTEAREVALEQCPPLQPQALPAGARVVLQTCLEIPPQLAGFTRRFAHALEGRAGFSGTYQGAFANSERYAYQTPEGMLYLAYVIAGNRVGMTYFTLDAAQGPRPGFQ
>NC_015387.1|WP_013703558.1|731811_733260_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MTPVTTVAELFALYRAPGPPHPVKGVTHDSRRVQPGFVYVALRGQRCDGHRFIPDAVQRGAVAIVGEEPLEPGVPYLRVPDARRALSRLAAAFYGFPSTRLFVIGVTGTDGKTTTSCLVHHLLTRTGRGAGLISTVGLRYGEETRLLEGHFTTPEAPEVQAALAEMVRRGLTHAVLETSSHALAQHRVADVAYDLAVWTNLSPEHLDFHGSLEAYFQAKAALVNRAGFSILNAGCPYAMRLTHRPHTTYGVQAGAYRAVRVRESTDGLRFTLEAPGFTGEAFLPMIGRYNVENALAALAAAHRAGVPLEEALPALARFSGVPGRMQILQAHPIRAVVDFAHTPKALAKALTALRPTTPGRLIVVIGAAGERDPAKRAPLGRTAVTLADFAVFTEEDARSEDVHAILQEMERGAREAGGVRGTHYALKPDRRDAIRYALSLARPGDTVVFAGKGHERTLERADETLPWDEAEEVRKALGIAID
>NC_015387.1|WP_013703557.1|731009_731762_-|Nif3-like-dinuclear-metal-center-hexameric-protein
MRRDELVNWLDEYLDLPRYPDLSLNGLQVEGRPEVTRVGVAVDAAAPVFEKALEAGVDFLIVHHGLFWGKPLAVTGPHKRRLELLFSGGINLYAAHLPLDAHPEVGNNAVLARELGLVDLEPFGEFKGVKIGFKGRFPVPESLAQIADKLGQLTGMQCLVHQGGQDPVERVGIVSGGAAWTVVEAAREGLELFITGEPKHEVFHETFERGMNAIYAGHYDTEVFGVKALAQKLQETFGLEWVFLDHPTGL
>NC_015387.1|WP_013703568.1|742958_743777_-|cyclase-family-protein
MCAPTVMDAVAARMTRRGFLGLLGAAALAGTVARAEKRVAVKGFTKVQDLTHPLSPNFPMWPGFDPIRITPLVTVEQNGFYGNRVDFWEHSGTHMDAPAHFDADGPTAEQLPVERLFAPLAVIHIAERAAKDPDAQLTPDDILAWERRYDRLPAGAFVAMYSGWEQHASNAVRYRNMDASGTMHFPGFHPDAAAMLIEEREITGIGVDTLSLDFGASTDFKTHLTVLPAGKYGLENLAHLGELPPAGATIIVGAPKHQGASGGPVRAFAVWD
>NC_015387.1|WP_013703569.1|743894_744320_-|disulfide-bond-formation-protein-B
MSTDQRNTFLLAFAWLVAIVATSGSLYFSEVRRFLPCELCWYQRILMYPLVVILGIANWYGDFAVRRYVLPLAVIGGTISLTHYLTQKVEGFALFPCKPPVPCANEYVNYFGFVTIPFMALTAFVLITLAMLLIRTRPHNR
>NC_015387.1|WP_013703570.1|744391_745306_-|signal-recognition-particle-docking-protein-FtsY
MSWFQRLKEGLKKTSQAIAQAVPWGGDPEEVLEELEFALIAADVGVEATQEILEEVRQSGKKDLREAVKQSLVLQLEPDARRAKLRKLGFTPNAKKAVVEPKGRVVLMVGVNGVGKTTTIAKLGRYYRQHGRSVMFCAGDTFRAAGGAQLGLWGERLGIPVIQGPEGSDPGALAFDAAQARKARGIDLLFVDTAGRLHTKHNLMEELKKIKRAIDKADPGEPGEVWLVLDAVTGQNGLQQAKRFHEAVGLTGVIVTKLDGTAKGGVLVPIVRELGVPIRFIGVGEGPDDLQPFDAGEFVEALLG
>NC_015387.1|WP_013703571.1|745302_746748_-|glutamate--tRNA-ligase
MVTTRIAPSPTGDPHVGTAYIAIFNYVWARKNNGKFIVRIEDTDRNRYVEGAEARIQEMIRWLGLDYDEGTDIGGPNGPYRQSERTAIYQAHAAKLIETGAAYRCFCTPERLEALREEQKKRGLPLGYDGHCRHIPPEEAEARAKAGEPHVVRLKVPRPGQTVVKDELRGLVTYDHAEVPDVVLLKSDGFPTYHLANVVDDHLMGVTDVIRGEEWLVSTPIHVLLYQAFGWEAPLWYHMPLLRAPGGAKLSKRTGHTSVDWYRERGILAEALMNYLSLMGFSMPDGREIFTLQELIEAFSWERVSLGGPVFDYEKLKWMNGKYIREVLTLEDLTQRVKPFLERAGLEWGSDAYLQRVVAAMRIRFETLEEFVEKARYFFTEAYPFEEKALKKLKAGLEYVVELKERLGTLPEMDPELTEPLIRGYAAEKGAKPGAVMQPLRAALTGTLQSPGMFELLELLGKDRVLKRLERAIQTAEAEEA
>NC_015387.1|WP_013703572.1|746767_747568_-|undecaprenyl-diphosphate-phosphatase
MDLELLRAIVLGAIQGFTEFLPISSSGFLVLGNHFLFDLERLPLWVDLATNSGTFLAAAWVLRREITTVARGFARGLTASQARHEEGWRLMLWLFLATLPAALLGLVLAPVFEALNTPRVAAVGFFITGTLLLLVPPQGGPKRTADAMTFWDALLAGLAQALALVPGISRSGSTIAVLLGRGLSPSFAARFSFLMYTLVSLGAMLLGIQEGVGKVPWGPLFGAFLSAFVFGLLGMRLLFGVLEAGHFRYFTPLLWALALLTLLSAA
>NC_015387.1|WP_013703573.1|747648_748041_-|30S-ribosomal-protein-S9
MALEQYYGTGRRKTAVARVFLRPGDGKITVNKQDFQDYFRGIIKAVSALEPLRVTGLMGRFDLYITVKGGGKSGQIDAIKLGLARALLQYDADLRAKLKPAGLLTRDAREVERKKYGKHKARRAPQYSKR
>NC_015387.1|WP_013703574.1|748040_748475_-|50S-ribosomal-protein-L13
MFKTYVPKNIEPKWVLIDAEGKTLGRLASEIAKILRGKHRPEYTPNMLTGDFVVVINAEKVRLTGKKLTDKYYTRYSGYPGGLRKIPVGEMLKKHPERVLQHAVKGMLPKGPLGRRMLKRLKVYAGPTHPHAAQKPEKLELEVK
>NC_015387.1|WP_013703576.1|749850_750402_+|hypothetical-protein
MQRFSFPWTRVERGAGVLAVVAVGVLQGGLTWRLVRLAHAANLTFPELLNTVPEVRVPYALSWFAAFAVVYAVWAGAATRSRTVLEVGEAGLRFVRPGLPVLGLGAREVRLEPGAVTRLVLEDYGMRARFWLEAEGVRFAVPLEAGVAEGGSEGTRGGRDWERHPLVQLVVARTGGRLEVKRR
>NC_015387.1|WP_013703577.1|750405_750711_+|4a-hydroxytetrahydrobiopterin-dehydratase
MRRLTREEIAAGLEGLEGWALVADRVEKTFGFASYADGVAFALRVALLAERMDHHPDALTIGWKRVVVAYVTHSVGGVTERDLEAARQVETVYARMFAPNG
>NC_015387.1|WP_013703578.1|750857_752054_+|argininosuccinate-synthase
MKIVLAYSGGLDTSIILKWLKETYGAEVIAFTADIGQGEEVEEARQKALATGATKAYALDLKEEFVREFVFPMMRAAPLYEGYYLLGTSIARPLIAKHLVAIAEREGAEAISHGATGKGNDQVRFELTAYALKPGIRVIAPWREWHFKGRSEMIAYAQDHGIPVPVTTEKPYSMDANLLHVSYEGGILEDPWAEPPTDMFRMTTHPEDAPDEPEYVEITFEAGDPVAVNGQRMSPAELLAALNRIGGRHGVGRVDLVENRFVGMKSRGVYETPGGTLLYHARRAVESLTLDREALHLRDTLAPKYAELVYNGFWFAPEREALQAMMDRIAQSVTGTARLKLYKGNAYIVGRKAPQSLYDPELASFEAEEVYNQKDAEGFIKLNALRLRVRAQAKQEAP

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Crispr_ID: NC_015387_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_6

959694-963140

TypeI-E

I-E,II-B

Consensus_repeat	Method
GTAGTCCCCACGCACGTGGGGATGGACC	PILER-CR
GTAGTCCCCACGCACGTGGGGATGGACCG	CRISPRCasFinder
GTAGTCCCCACGCACGTGGGGATGGACCG	CRT

56 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,WYL

The CRISPR arrays of NC_015387_6

>merge|NC_015387|6|959694-963140|PILER-CR,CRISPRCasFinder,CRT
GTAGTCCCCACGCACGTGGGGATGGACCGAGTAACGTTTGGGGCGTGGCTACGTGGTCTAAGTAGTCCCCACGCACGTGGGGATGGACCGCCTGGGCCGCACCGATCCAGGCCGCCCAAGCGGTAGTCCCCACGCACGTGGGGATGGACCGAGAAGGCGCAAACGCAAGAAAACCCCGTATAAGTAGTCCCCACGCACGTGGGGATGGACCGTACCTGGACCCACCCCAAACACCCGAAACGAAGTAGTCCCCACGCACGTGGGGATGGACCGGGGGGGTCTTTCATGAATGGCGCTATGGGTTTGTAGTCCCCACGCACGTGGGGATGGACCGCCTTCACTAACCAGAAAAACGAAGAAAAAAGCGTAGTCCCCACGCACGTGGGGATGGACCGTGGCTGCGGCGCGTGGCTCACGCGTGCGGGGTGGTAGTCCCCACGCACGTGGGGATGGACCGGCGCGGCTCGAGCCCGTCCAGCACGCAAAACCGTAGTCCCCACGCACGTGGGGATGGACCGCCCCGCTCGAGCTGCCGGACCTCCTCCTCACTGTAGTCCCCACGCACGTGGGGATGGACCGAGATTGGGGAAACCGCTAACGTCCAGGAAACCGTAGTCCCCACGCACGTGGGGATGGACCGTCCACGGTCTCCTCCAGGACCGCGCCCCGGTCGTAGTCCCCACGCACGTGGGGATGGACCGTCTTCGTGGAGGCGGGTTGGGCTGAACCCATTGTAGTCCCCACGCACGTGGGGATGGACCGGCCAAGTGGGAACGCAAACCCTAATATTTATGTAGTCCCCACGCACGTGGGGATGGACCTCGGCCTTATCCGTGTTGGACGTGGGGGTAATCGTAGTCCCCACGCACGTGGGGATGGACCGATCAGCACCTAAGAGTGAGGTGATTAGTAATGGTAGTCCCCACGCACGTGGGGATGGACCAGAGGGACTACGCGAGGCGCAAAACCTGCTCTCGTAGTCCCCACGCACGTGGGGATGGACCGCTAGAGGTCAAGCCCATCGCGGGGTGGCTAGAGTAGTCCCCACGCACGTGGGGATGGACCGTGCCGGCTCGCTCGGGGTGGACTCGTACCTCGGTAGTCCCCACGCACGTGGGGATGGACCGTATACCCTAGTGGATATCGCGCAACTGGACACGTAGTCCCCACGCACGTGGGGATGGACCCTCTAGCCCCTGCAACACAAAGCCCCGCCCCCAGTAGTCCCCACGCACGTGGGGATGGACCAGCTCACGCCCCTGGAGCGCGTGACGTACTACAGTAGTCCCCACGCACGTGGGGATGGACCAGGACCTCCTCGCCCGTCTCCGCGTCCACGGTTCGTAGTCCCCACGCACGTGGGGATGGACCGAACGAGCACCGCGCCGCGATCATCCTGAACGCGTAGTCCCCACGCACGTGGGGATGGACCTCACGCCGAACCTCAGCAAGAACCGGGACTTCCGTAGTCCCCACGCACGTGGGGATGGACCGCTTGCCCGCGCGCGTGAGGTTGAGGCTATCGAGTAGTCCCCACGCACGTGGGGATGGACCGAACCCAGTTCCGCTCATCAAGCGCACTGAGGTGTAGTCCCCACGCACGTGGGGATGGACCTTGCTCCACAGGCCGAGCAGCGTGCGGGATTGCGTAGTCCCCACGCACGTGGGGATGGACCGAGGGTGCCGCTTACCTACAAGAGCGTCAAGGTGTAGTCCCCACGCACGTGGGGATGGACCGTTTAGTCTCGAGCTCGCTGCTCCGCGCCTCAGGTAGTCCCCACGCACGTGGGGATGGACCGCACAACGTAACGCCCGGAATGTGCCTGAGGGGGTAGTCCCCACGCACGTGGGGATGGACCGCTGGAGCGCCATTGCCTCGCCGATGCGGGGGCGTAGTCCCCACGCACGTGGGGATGGACCGGGACATAACCCTAACCTCACGCCCGAGAGCCCGTAGTCCCCACGCACGTGGGGATGGACCGGGTAGCCCGGTACTCATGCCATGCTTTTTGAAGTAGTCCCCACGCACGTGGGGATGGACCGATCTTCCCCAAGTAACGCGGATGAGGTACCCCGTAGTCCCCACGCACGTGGGGATGGACCGTAACGCGTGAAGTACTTGACGCGCTTTAGTCCGTAGTCCCCACGCACGTGGGGATGGACCGCATACAATAAATCCGCATACGCACTTATTCCGGTAGTCCCCACGCACGTGGGGATGGACCAGAGTATCCGCAAGCACGTCAAAAGCAAAAGAGGTAGTCCCCACGCACGTGGGGATGGACCGACCTCACCCCGCTAGAGATTCAGTCCTGGGCCGTAGTCCCCACGCACGTGGGGATGGACCAAGTGGGAGGAAGCCAAAGCCACCAGGGCCGTTGTAGTCCCCACGCACGTGGGGATGGACCGCCCTCCTGGACTGGTTACGGCAGGACCCGCCCGTAGTCCCCACGCACGTGGGGATGGACCGTCTGCGGAGTCAGAGCCGATGGCCCGGGCCATGTAGTCCCCACGCACGTGGGGATGGACCGAACGCCTTGAGCACCACGCCGAACGCGTCCGTAGTAGTCCCCACGCACGTGGGGATGGACCGACGTGAACGATCTGCTCAGCGCGTGGGCGCTCGTAGTCCCCACGCACGTGGGGATGGACCGGGATCGAAATGGACAAGGCCGGATGGGCGATAGTAGTCCCCACGCACGTGGGGATGGACCGGTCCAGATAGGCGAGGTACCTGTGTTCCCCGTGTAGTCCCCACGCACGTGGGGATGGACCGGAATACCATACACGGGCGATGAAATAAACCGCGTAGTCCCCACGCACGTGGGGATGGACCGTCTACGAATTATTATGCGAAGAACTTCCGCCCGTAGTCCCCACGCACGTGGGGATGGACCGTTGAGGGGTTGTAGGCCCAGGTTGCGTATTGAGTAGTCCCCACGCACGTGGGGATGGACCGCTGGGAGCCGTCAGCGGGCTCTCCATCGGTTAGTAGTCCCCACGCACGTGGGGATGGACCGCCCCTGCGGGAGGTCACGGTACGTGTGCGCTCGTAGTCCCCACGCACGTGGGGATGGACCAGCCGTCCGTGCGTTCCTCATCCGCGAACTCCAGTAGTCCCCACGCACGTGGGGATGGACCGTACCGGAATGGCCGCTTAATGTCCGGGTTTTCGTAGTCCCCACGCACGTGGGGATGGACCGAAAAAAGTCGTGAGCACGCCCGTCACGGGCAGGTAGTCCCCACGCACGTGGGGATGGACCGTTCGCCACGCCGCGCACCATGCGCCGCGGGGCGTAGTCCCCACGCACGTGGGGATGGACCGGATAATCTGCTACAATTCTACGCCATGAATACGTAGTCCCCACGCACGTGGGGATGGACCGATGCTGAATGGGCATATACACGCGGTTTTGACGTAGTCCCCACGCACGTGGGGATGGACCG

>NC_015387|6|3|959694-963139|PILER-CR
GTAGTCCCCACGCACGTGGGGATGGACC	GAGTAACGTTTGGGGCGTGGCTACGTGGTCTAA
GTAGTCCCCACGCACGTGGGGATGGACC	GCCTGGGCCGCACCGATCCAGGCCGCCCAAGCG
GTAGTCCCCACGCACGTGGGGATGGACC	GAGAAGGCGCAAACGCAAGAAAACCCCGTATAA
GTAGTCCCCACGCACGTGGGGATGGACC	GTACCTGGACCCACCCCAAACACCCGAAACGAA
GTAGTCCCCACGCACGTGGGGATGGACC	GGGGGGGTCTTTCATGAATGGCGCTATGGGTTT
GTAGTCCCCACGCACGTGGGGATGGACC	GCCTTCACTAACCAGAAAAACGAAGAAAAAAGC
GTAGTCCCCACGCACGTGGGGATGGACC	GTGGCTGCGGCGCGTGGCTCACGCGTGCGGGGTG
GTAGTCCCCACGCACGTGGGGATGGACC	GGCGCGGCTCGAGCCCGTCCAGCACGCAAAACC
GTAGTCCCCACGCACGTGGGGATGGACC	GCCCCGCTCGAGCTGCCGGACCTCCTCCTCACT
GTAGTCCCCACGCACGTGGGGATGGACC	GAGATTGGGGAAACCGCTAACGTCCAGGAAACC
GTAGTCCCCACGCACGTGGGGATGGACC	GTCCACGGTCTCCTCCAGGACCGCGCCCCGGTC
GTAGTCCCCACGCACGTGGGGATGGACC	GTCTTCGTGGAGGCGGGTTGGGCTGAACCCATT
GTAGTCCCCACGCACGTGGGGATGGACC	GGCCAAGTGGGAACGCAAACCCTAATATTTAT
GTAGTCCCCACGCACGTGGGGATGGACC	TCGGCCTTATCCGTGTTGGACGTGGGGGTAATC
GTAGTCCCCACGCACGTGGGGATGGACC	GATCAGCACCTAAGAGTGAGGTGATTAGTAATG
GTAGTCCCCACGCACGTGGGGATGGACC	AGAGGGACTACGCGAGGCGCAAAACCTGCTCTC
GTAGTCCCCACGCACGTGGGGATGGACC	GCTAGAGGTCAAGCCCATCGCGGGGTGGCTAGA
GTAGTCCCCACGCACGTGGGGATGGACC	GTGCCGGCTCGCTCGGGGTGGACTCGTACCTCG
GTAGTCCCCACGCACGTGGGGATGGACC	GTATACCCTAGTGGATATCGCGCAACTGGACAC
GTAGTCCCCACGCACGTGGGGATGGACC	CTCTAGCCCCTGCAACACAAAGCCCCGCCCCCA
GTAGTCCCCACGCACGTGGGGATGGACC	AGCTCACGCCCCTGGAGCGCGTGACGTACTACA
GTAGTCCCCACGCACGTGGGGATGGACC	AGGACCTCCTCGCCCGTCTCCGCGTCCACGGTTC
GTAGTCCCCACGCACGTGGGGATGGACC	GAACGAGCACCGCGCCGCGATCATCCTGAACGC
GTAGTCCCCACGCACGTGGGGATGGACC	TCACGCCGAACCTCAGCAAGAACCGGGACTTCC
GTAGTCCCCACGCACGTGGGGATGGACC	GCTTGCCCGCGCGCGTGAGGTTGAGGCTATCGA
GTAGTCCCCACGCACGTGGGGATGGACC	GAACCCAGTTCCGCTCATCAAGCGCACTGAGGT
GTAGTCCCCACGCACGTGGGGATGGACC	TTGCTCCACAGGCCGAGCAGCGTGCGGGATTGC
GTAGTCCCCACGCACGTGGGGATGGACC	GAGGGTGCCGCTTACCTACAAGAGCGTCAAGGT
GTAGTCCCCACGCACGTGGGGATGGACC	GTTTAGTCTCGAGCTCGCTGCTCCGCGCCTCAG
GTAGTCCCCACGCACGTGGGGATGGACC	GCACAACGTAACGCCCGGAATGTGCCTGAGGGG
GTAGTCCCCACGCACGTGGGGATGGACC	GCTGGAGCGCCATTGCCTCGCCGATGCGGGGGC
GTAGTCCCCACGCACGTGGGGATGGACC	GGGACATAACCCTAACCTCACGCCCGAGAGCCC
GTAGTCCCCACGCACGTGGGGATGGACC	GGGTAGCCCGGTACTCATGCCATGCTTTTTGAA
GTAGTCCCCACGCACGTGGGGATGGACC	GATCTTCCCCAAGTAACGCGGATGAGGTACCCC
GTAGTCCCCACGCACGTGGGGATGGACC	GTAACGCGTGAAGTACTTGACGCGCTTTAGTCC
GTAGTCCCCACGCACGTGGGGATGGACC	GCATACAATAAATCCGCATACGCACTTATTCCG
GTAGTCCCCACGCACGTGGGGATGGACC	AGAGTATCCGCAAGCACGTCAAAAGCAAAAGAG
GTAGTCCCCACGCACGTGGGGATGGACC	GACCTCACCCCGCTAGAGATTCAGTCCTGGGCC
GTAGTCCCCACGCACGTGGGGATGGACC	AAGTGGGAGGAAGCCAAAGCCACCAGGGCCGTT
GTAGTCCCCACGCACGTGGGGATGGACC	GCCCTCCTGGACTGGTTACGGCAGGACCCGCCC
GTAGTCCCCACGCACGTGGGGATGGACC	GTCTGCGGAGTCAGAGCCGATGGCCCGGGCCAT
GTAGTCCCCACGCACGTGGGGATGGACC	GAACGCCTTGAGCACCACGCCGAACGCGTCCGTA
GTAGTCCCCACGCACGTGGGGATGGACC	GACGTGAACGATCTGCTCAGCGCGTGGGCGCTC
GTAGTCCCCACGCACGTGGGGATGGACC	GGGATCGAAATGGACAAGGCCGGATGGGCGATA
GTAGTCCCCACGCACGTGGGGATGGACC	GGTCCAGATAGGCGAGGTACCTGTGTTCCCCGT
GTAGTCCCCACGCACGTGGGGATGGACC	GGAATACCATACACGGGCGATGAAATAAACCGC
GTAGTCCCCACGCACGTGGGGATGGACC	GTCTACGAATTATTATGCGAAGAACTTCCGCCC
GTAGTCCCCACGCACGTGGGGATGGACC	GTTGAGGGGTTGTAGGCCCAGGTTGCGTATTGA
GTAGTCCCCACGCACGTGGGGATGGACC	GCTGGGAGCCGTCAGCGGGCTCTCCATCGGTTA
GTAGTCCCCACGCACGTGGGGATGGACC	GCCCCTGCGGGAGGTCACGGTACGTGTGCGCTC
GTAGTCCCCACGCACGTGGGGATGGACC	AGCCGTCCGTGCGTTCCTCATCCGCGAACTCCA
GTAGTCCCCACGCACGTGGGGATGGACC	GTACCGGAATGGCCGCTTAATGTCCGGGTTTTC
GTAGTCCCCACGCACGTGGGGATGGACC	GAAAAAAGTCGTGAGCACGCCCGTCACGGGCAG
GTAGTCCCCACGCACGTGGGGATGGACC	GTTCGCCACGCCGCGCACCATGCGCCGCGGGGC
GTAGTCCCCACGCACGTGGGGATGGACC	GGATAATCTGCTACAATTCTACGCCATGAATAC
GTAGTCCCCACGCACGTGGGGATGGACC	GATGCTGAATGGGCATATACACGCGGTTTTGAC
GTAGTCCCCACGCACGTGGGGATGGACC

>NC_015387|6|6|959694-963140|CRISPRCasFinder
GTAGTCCCCACGCACGTGGGGATGGACCG	AGTAACGTTTGGGGCGTGGCTACGTGGTCTAA
GTAGTCCCCACGCACGTGGGGATGGACCG	CCTGGGCCGCACCGATCCAGGCCGCCCAAGCG
GTAGTCCCCACGCACGTGGGGATGGACCG	AGAAGGCGCAAACGCAAGAAAACCCCGTATAA
GTAGTCCCCACGCACGTGGGGATGGACCG	TACCTGGACCCACCCCAAACACCCGAAACGAA
GTAGTCCCCACGCACGTGGGGATGGACCG	GGGGGGTCTTTCATGAATGGCGCTATGGGTTT
GTAGTCCCCACGCACGTGGGGATGGACCG	CCTTCACTAACCAGAAAAACGAAGAAAAAAGC
GTAGTCCCCACGCACGTGGGGATGGACCG	TGGCTGCGGCGCGTGGCTCACGCGTGCGGGGTG
GTAGTCCCCACGCACGTGGGGATGGACCG	GCGCGGCTCGAGCCCGTCCAGCACGCAAAACC
GTAGTCCCCACGCACGTGGGGATGGACCG	CCCCGCTCGAGCTGCCGGACCTCCTCCTCACT
GTAGTCCCCACGCACGTGGGGATGGACCG	AGATTGGGGAAACCGCTAACGTCCAGGAAACC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCCACGGTCTCCTCCAGGACCGCGCCCCGGTC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCTTCGTGGAGGCGGGTTGGGCTGAACCCATT
GTAGTCCCCACGCACGTGGGGATGGACCG	GCCAAGTGGGAACGCAAACCCTAATATTTAT
GTAGTCCCCACGCACGTGGGGATGGACCT	CGGCCTTATCCGTGTTGGACGTGGGGGTAATC
GTAGTCCCCACGCACGTGGGGATGGACCG	ATCAGCACCTAAGAGTGAGGTGATTAGTAATG
GTAGTCCCCACGCACGTGGGGATGGACCA	GAGGGACTACGCGAGGCGCAAAACCTGCTCTC
GTAGTCCCCACGCACGTGGGGATGGACCG	CTAGAGGTCAAGCCCATCGCGGGGTGGCTAGA
GTAGTCCCCACGCACGTGGGGATGGACCG	TGCCGGCTCGCTCGGGGTGGACTCGTACCTCG
GTAGTCCCCACGCACGTGGGGATGGACCG	TATACCCTAGTGGATATCGCGCAACTGGACAC
GTAGTCCCCACGCACGTGGGGATGGACCC	TCTAGCCCCTGCAACACAAAGCCCCGCCCCCA
GTAGTCCCCACGCACGTGGGGATGGACCA	GCTCACGCCCCTGGAGCGCGTGACGTACTACA
GTAGTCCCCACGCACGTGGGGATGGACCA	GGACCTCCTCGCCCGTCTCCGCGTCCACGGTTC
GTAGTCCCCACGCACGTGGGGATGGACCG	AACGAGCACCGCGCCGCGATCATCCTGAACGC
GTAGTCCCCACGCACGTGGGGATGGACCT	CACGCCGAACCTCAGCAAGAACCGGGACTTCC
GTAGTCCCCACGCACGTGGGGATGGACCG	CTTGCCCGCGCGCGTGAGGTTGAGGCTATCGA
GTAGTCCCCACGCACGTGGGGATGGACCG	AACCCAGTTCCGCTCATCAAGCGCACTGAGGT
GTAGTCCCCACGCACGTGGGGATGGACCT	TGCTCCACAGGCCGAGCAGCGTGCGGGATTGC
GTAGTCCCCACGCACGTGGGGATGGACCG	AGGGTGCCGCTTACCTACAAGAGCGTCAAGGT
GTAGTCCCCACGCACGTGGGGATGGACCG	TTTAGTCTCGAGCTCGCTGCTCCGCGCCTCAG
GTAGTCCCCACGCACGTGGGGATGGACCG	CACAACGTAACGCCCGGAATGTGCCTGAGGGG
GTAGTCCCCACGCACGTGGGGATGGACCG	CTGGAGCGCCATTGCCTCGCCGATGCGGGGGC
GTAGTCCCCACGCACGTGGGGATGGACCG	GGACATAACCCTAACCTCACGCCCGAGAGCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	GGTAGCCCGGTACTCATGCCATGCTTTTTGAA
GTAGTCCCCACGCACGTGGGGATGGACCG	ATCTTCCCCAAGTAACGCGGATGAGGTACCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	TAACGCGTGAAGTACTTGACGCGCTTTAGTCC
GTAGTCCCCACGCACGTGGGGATGGACCG	CATACAATAAATCCGCATACGCACTTATTCCG
GTAGTCCCCACGCACGTGGGGATGGACCA	GAGTATCCGCAAGCACGTCAAAAGCAAAAGAG
GTAGTCCCCACGCACGTGGGGATGGACCG	ACCTCACCCCGCTAGAGATTCAGTCCTGGGCC
GTAGTCCCCACGCACGTGGGGATGGACCA	AGTGGGAGGAAGCCAAAGCCACCAGGGCCGTT
GTAGTCCCCACGCACGTGGGGATGGACCG	CCCTCCTGGACTGGTTACGGCAGGACCCGCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCTGCGGAGTCAGAGCCGATGGCCCGGGCCAT
GTAGTCCCCACGCACGTGGGGATGGACCG	AACGCCTTGAGCACCACGCCGAACGCGTCCGTA
GTAGTCCCCACGCACGTGGGGATGGACCG	ACGTGAACGATCTGCTCAGCGCGTGGGCGCTC
GTAGTCCCCACGCACGTGGGGATGGACCG	GGATCGAAATGGACAAGGCCGGATGGGCGATA
GTAGTCCCCACGCACGTGGGGATGGACCG	GTCCAGATAGGCGAGGTACCTGTGTTCCCCGT
GTAGTCCCCACGCACGTGGGGATGGACCG	GAATACCATACACGGGCGATGAAATAAACCGC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCTACGAATTATTATGCGAAGAACTTCCGCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	TTGAGGGGTTGTAGGCCCAGGTTGCGTATTGA
GTAGTCCCCACGCACGTGGGGATGGACCG	CTGGGAGCCGTCAGCGGGCTCTCCATCGGTTA
GTAGTCCCCACGCACGTGGGGATGGACCG	CCCCTGCGGGAGGTCACGGTACGTGTGCGCTC
GTAGTCCCCACGCACGTGGGGATGGACCA	GCCGTCCGTGCGTTCCTCATCCGCGAACTCCA
GTAGTCCCCACGCACGTGGGGATGGACCG	TACCGGAATGGCCGCTTAATGTCCGGGTTTTC
GTAGTCCCCACGCACGTGGGGATGGACCG	AAAAAAGTCGTGAGCACGCCCGTCACGGGCAG
GTAGTCCCCACGCACGTGGGGATGGACCG	TTCGCCACGCCGCGCACCATGCGCCGCGGGGC
GTAGTCCCCACGCACGTGGGGATGGACCG	GATAATCTGCTACAATTCTACGCCATGAATAC
GTAGTCCCCACGCACGTGGGGATGGACCG	ATGCTGAATGGGCATATACACGCGGTTTTGAC
GTAGTCCCCACGCACGTGGGGATGGACCG

>NC_015387|6|2|959694-963140|CRT
GTAGTCCCCACGCACGTGGGGATGGACCG	AGTAACGTTTGGGGCGTGGCTACGTGGTCTAA
GTAGTCCCCACGCACGTGGGGATGGACCG	CCTGGGCCGCACCGATCCAGGCCGCCCAAGCG
GTAGTCCCCACGCACGTGGGGATGGACCG	AGAAGGCGCAAACGCAAGAAAACCCCGTATAA
GTAGTCCCCACGCACGTGGGGATGGACCG	TACCTGGACCCACCCCAAACACCCGAAACGAA
GTAGTCCCCACGCACGTGGGGATGGACCG	GGGGGGTCTTTCATGAATGGCGCTATGGGTTT
GTAGTCCCCACGCACGTGGGGATGGACCG	CCTTCACTAACCAGAAAAACGAAGAAAAAAGC
GTAGTCCCCACGCACGTGGGGATGGACCG	TGGCTGCGGCGCGTGGCTCACGCGTGCGGGGTG
GTAGTCCCCACGCACGTGGGGATGGACCG	GCGCGGCTCGAGCCCGTCCAGCACGCAAAACC
GTAGTCCCCACGCACGTGGGGATGGACCG	CCCCGCTCGAGCTGCCGGACCTCCTCCTCACT
GTAGTCCCCACGCACGTGGGGATGGACCG	AGATTGGGGAAACCGCTAACGTCCAGGAAACC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCCACGGTCTCCTCCAGGACCGCGCCCCGGTC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCTTCGTGGAGGCGGGTTGGGCTGAACCCATT
GTAGTCCCCACGCACGTGGGGATGGACCG	GCCAAGTGGGAACGCAAACCCTAATATTTAT
GTAGTCCCCACGCACGTGGGGATGGACCT	CGGCCTTATCCGTGTTGGACGTGGGGGTAATC
GTAGTCCCCACGCACGTGGGGATGGACCG	ATCAGCACCTAAGAGTGAGGTGATTAGTAATG
GTAGTCCCCACGCACGTGGGGATGGACCA	GAGGGACTACGCGAGGCGCAAAACCTGCTCTC
GTAGTCCCCACGCACGTGGGGATGGACCG	CTAGAGGTCAAGCCCATCGCGGGGTGGCTAGA
GTAGTCCCCACGCACGTGGGGATGGACCG	TGCCGGCTCGCTCGGGGTGGACTCGTACCTCG
GTAGTCCCCACGCACGTGGGGATGGACCG	TATACCCTAGTGGATATCGCGCAACTGGACAC
GTAGTCCCCACGCACGTGGGGATGGACCC	TCTAGCCCCTGCAACACAAAGCCCCGCCCCCA
GTAGTCCCCACGCACGTGGGGATGGACCA	GCTCACGCCCCTGGAGCGCGTGACGTACTACA
GTAGTCCCCACGCACGTGGGGATGGACCA	GGACCTCCTCGCCCGTCTCCGCGTCCACGGTTC
GTAGTCCCCACGCACGTGGGGATGGACCG	AACGAGCACCGCGCCGCGATCATCCTGAACGC
GTAGTCCCCACGCACGTGGGGATGGACCT	CACGCCGAACCTCAGCAAGAACCGGGACTTCC
GTAGTCCCCACGCACGTGGGGATGGACCG	CTTGCCCGCGCGCGTGAGGTTGAGGCTATCGA
GTAGTCCCCACGCACGTGGGGATGGACCG	AACCCAGTTCCGCTCATCAAGCGCACTGAGGT
GTAGTCCCCACGCACGTGGGGATGGACCT	TGCTCCACAGGCCGAGCAGCGTGCGGGATTGC
GTAGTCCCCACGCACGTGGGGATGGACCG	AGGGTGCCGCTTACCTACAAGAGCGTCAAGGT
GTAGTCCCCACGCACGTGGGGATGGACCG	TTTAGTCTCGAGCTCGCTGCTCCGCGCCTCAG
GTAGTCCCCACGCACGTGGGGATGGACCG	CACAACGTAACGCCCGGAATGTGCCTGAGGGG
GTAGTCCCCACGCACGTGGGGATGGACCG	CTGGAGCGCCATTGCCTCGCCGATGCGGGGGC
GTAGTCCCCACGCACGTGGGGATGGACCG	GGACATAACCCTAACCTCACGCCCGAGAGCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	GGTAGCCCGGTACTCATGCCATGCTTTTTGAA
GTAGTCCCCACGCACGTGGGGATGGACCG	ATCTTCCCCAAGTAACGCGGATGAGGTACCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	TAACGCGTGAAGTACTTGACGCGCTTTAGTCC
GTAGTCCCCACGCACGTGGGGATGGACCG	CATACAATAAATCCGCATACGCACTTATTCCG
GTAGTCCCCACGCACGTGGGGATGGACCA	GAGTATCCGCAAGCACGTCAAAAGCAAAAGAG
GTAGTCCCCACGCACGTGGGGATGGACCG	ACCTCACCCCGCTAGAGATTCAGTCCTGGGCC
GTAGTCCCCACGCACGTGGGGATGGACCA	AGTGGGAGGAAGCCAAAGCCACCAGGGCCGTT
GTAGTCCCCACGCACGTGGGGATGGACCG	CCCTCCTGGACTGGTTACGGCAGGACCCGCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCTGCGGAGTCAGAGCCGATGGCCCGGGCCAT
GTAGTCCCCACGCACGTGGGGATGGACCG	AACGCCTTGAGCACCACGCCGAACGCGTCCGTA
GTAGTCCCCACGCACGTGGGGATGGACCG	ACGTGAACGATCTGCTCAGCGCGTGGGCGCTC
GTAGTCCCCACGCACGTGGGGATGGACCG	GGATCGAAATGGACAAGGCCGGATGGGCGATA
GTAGTCCCCACGCACGTGGGGATGGACCG	GTCCAGATAGGCGAGGTACCTGTGTTCCCCGT
GTAGTCCCCACGCACGTGGGGATGGACCG	GAATACCATACACGGGCGATGAAATAAACCGC
GTAGTCCCCACGCACGTGGGGATGGACCG	TCTACGAATTATTATGCGAAGAACTTCCGCCC
GTAGTCCCCACGCACGTGGGGATGGACCG	TTGAGGGGTTGTAGGCCCAGGTTGCGTATTGA
GTAGTCCCCACGCACGTGGGGATGGACCG	CTGGGAGCCGTCAGCGGGCTCTCCATCGGTTA
GTAGTCCCCACGCACGTGGGGATGGACCG	CCCCTGCGGGAGGTCACGGTACGTGTGCGCTC
GTAGTCCCCACGCACGTGGGGATGGACCA	GCCGTCCGTGCGTTCCTCATCCGCGAACTCCA
GTAGTCCCCACGCACGTGGGGATGGACCG	TACCGGAATGGCCGCTTAATGTCCGGGTTTTC
GTAGTCCCCACGCACGTGGGGATGGACCG	AAAAAAGTCGTGAGCACGCCCGTCACGGGCAG
GTAGTCCCCACGCACGTGGGGATGGACCG	TTCGCCACGCCGCGCACCATGCGCCGCGGGGC
GTAGTCCCCACGCACGTGGGGATGGACCG	GATAATCTGCTACAATTCTACGCCATGAATAC
GTAGTCCCCACGCACGTGGGGATGGACCG	ATGCTGAATGGGCATATACACGCGGTTTTGAC
GTAGTCCCCACGCACGTGGGGATGGACCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013703773.1\|957718_958339_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|378050
NC_015387.1\|WP_013703780.1\|967490_967982_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013703774.1\|958347_959319_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_015387.1\|WP_013703767.1\|948847_949816_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_015387.1\|WP_013703786.1\|974819_975188_+\|DUF393-domain-containing-protein	unknown	unknown	gnl\|CDD\|367833
NC_015387.1\|WP_013703782.1\|968589_970620_-\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NC_015387.1\|WP_013703770.1\|955452_955959_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|237559
NC_015387.1\|WP_013703772.1\|957078_957744_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|378243
NC_015387.1\|WP_041658284.1\|965250_965985_+\|aminotransferase-class-IV	unknown	unknown	gnl\|CDD\|376449
NC_015387.1\|WP_013703783.1\|970708_971833_+\|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380577
NC_015387.1\|WP_148230459.1\|973548_974817_+\|DUF3179-domain-containing-protein	unknown	unknown	gnl\|CDD\|371498
NC_015387.1\|WP_013703768.1\|949825_952600_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NC_015387.1\|WP_013703775.1\|959278_959635_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NC_015387.1\|WP_013703766.1\|948148_948685_-\|DUF2179-domain-containing-protein	unknown	unknown	gnl\|CDD\|235234
NC_015387.1\|WP_013703781.1\|967993_968584_-\|SCO-family-protein	unknown	unknown	gnl\|CDD\|239266
NC_015387.1\|WP_083804443.1\|953986_955456_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NC_015387.1\|WP_013703784.1\|971891_973409_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226364
NC_015387.1\|WP_013703771.1\|955955_957077_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NC_015387.1\|WP_013703779.1\|966361_967510_+\|homoserine-O-acetyltransferase	unknown	unknown	gnl\|CDD\|273596
NC_015387.1\|WP_013703777.1\|963380_965264_+\|aminodeoxychorismate-components-I/II	unknown	unknown	gnl\|CDD\|223225

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013703773.1\|957718_958339_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.95058e-65
NC_015387.1\|WP_013703774.1\|958347_959319_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.14992e-134
NC_015387.1\|WP_013703767.1\|948847_949816_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.17021e-32
NC_015387.1\|WP_013703786.1\|974819_975188_+\|DUF393-domain-containing-protein	gnl\|CDD\|367833	pfam04134, DUF393, Protein of unknown function, DUF393. Members of this family have two highly conserved cysteine residues near their N-terminus. The function of these proteins is unknown.	2.2798e-19
NC_015387.1\|WP_013703782.1\|968589_970620_-\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_015387.1\|WP_013703770.1\|955452_955959_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|237559	PRK13921, PRK13921, CRISPR-associated Cse2 family protein; Provisional.	3.44236e-60
NC_015387.1\|WP_013703772.1\|957078_957744_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	2.27766e-51
NC_015387.1\|WP_041658284.1\|965250_965985_+\|aminotransferase-class-IV	gnl\|CDD\|376449	pfam01063, Aminotran_4, Amino-transferase class IV. The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.	4.90552e-35
NC_015387.1\|WP_013703783.1\|970708_971833_+\|BMP-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380577	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. The PnrA lipoprotein, also known as Tp0319 or TmpC, represents a novel family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC) transport system (pnrABCDE). It shows a striking structural similarity to another basic membrane lipoprotein Med which regulates the competence transcription factor gene, comK, in Bacillus subtilis. The members of PnrA-like subgroup are likely to have similar nucleoside-binding functions and a similar type 1 periplasmic sugar-binding protein-like fold.	4.84587e-101
NC_015387.1\|WP_148230459.1\|973548_974817_+\|DUF3179-domain-containing-protein	gnl\|CDD\|371498	pfam11376, DUF3179, Protein of unknown function (DUF3179). This family of proteins has no known function.	2.43792e-110
NC_015387.1\|WP_013703768.1\|949825_952600_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	3.16278e-97
NC_015387.1\|WP_013703775.1\|959278_959635_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.48436e-41
NC_015387.1\|WP_013703766.1\|948148_948685_-\|DUF2179-domain-containing-protein	gnl\|CDD\|235234	PRK04164, PRK04164, hypothetical protein; Provisional.	3.9144e-59
NC_015387.1\|WP_013703781.1\|967993_968584_-\|SCO-family-protein	gnl\|CDD\|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	2.29488e-58
NC_015387.1\|WP_083804443.1\|953986_955456_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	6.25543e-110
NC_015387.1\|WP_013703784.1\|971891_973409_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226364	COG3845, COG3845, ABC-type uncharacterized transport systems, ATPase components [General function prediction only].	0
NC_015387.1\|WP_013703771.1\|955955_957077_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	1.62853e-156
NC_015387.1\|WP_013703779.1\|966361_967510_+\|homoserine-O-acetyltransferase	gnl\|CDD\|273596	TIGR01392, Homoserine_O-acetyltransferase, homoserine O-acetyltransferase. This family describes homoserine-O-acetyltransferase, an enzyme of methionine biosynthesis. This model has been rebuilt to identify sequences more broadly, including a number of sequences suggested to be homoserine O-acetyltransferase based on proximity to other Met biosynthesis genes. [Amino acid biosynthesis, Aspartate family].	1.19201e-149
NC_015387.1\|WP_013703777.1\|963380_965264_+\|aminodeoxychorismate-components-I/II	gnl\|CDD\|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	7.57852e-136

>NC_015387.1|WP_013703775.1|959278_959635_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MVVMILEKVPRSLRGELTRWLVEVDTGVFVGRVSAMVRDLLWEKVVEKAGEGRCAMAYRTNNEQGFALKLHGYQDRSLRDFDGIVLVAVQNAKALRKARKLKRLQERMREDLDNTTLE
>NC_015387.1|WP_013703774.1|958347_959319_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MPPVPNTRNLKELPKFRDGLSYLYVEHAFIEQEAQGIAIYDQEGATLVPVAALGVLFLGPGTRITHAAIRALAGNGCTVAWIGEGFARFYAQGLGDTRSARRLYLQARAWADPKLHLEVVLRLYRKRFADPLPEGITLKQIRGFEGVRVRTAYARWSRETGVPWHGRSYDRRDWGNSDPVNRALSAGAAYLYGLAHAAIVSSGFSPALGFIHTGKLLSFVYDLADLYKTEVLIPTAFLTVAESEVEVERRVRRALRERIQEVRLLERMVEDLLDLFSGLGLPEEKDLVEGDPTYPGGLWDLEGEVEGGVAYGGDDSRESAEEP
>NC_015387.1|WP_013703773.1|957718_958339_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MWISKLVLNPRSKAVRRDLANPYEMHRTLSRAVAEALGTQKERLLWRLEPTRATEPPVVLVQTLTEPNWGALETDYYAEVFPPKPFNPHLRPGQTLRFRLRANPAKRVARTGKRIALKNPEEKLAWLARRLEEGGFRLLGGENGYRARILQDVFLEARKKEALLQVQAVLFEGILEVLDPEKARATLERGVGPGKALGLGLLSLAP
>NC_015387.1|WP_013703772.1|957078_957744_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MPTLLLRLQGPMQSWGTRSRFDHRDTWPYPTKSGVLGLLAAALGRDRKEDISDLAALRMGVRVDQKGVLKVDYQTARNVLAADGRALRDVQSWRYYLSGAAFLAGVEGTEELLQQIHQALRNPRFPLYLGRKSYLPSPPPYLPDGLRPEELEEALRGYPYLLKEKPREDLLLALEAPPEQGRLVYDQPLAPFAQRRFGARYVREIVLPKEEVRLVDQQAGT
>NC_015387.1|WP_013703771.1|955955_957077_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MKLLEVHILQTVAPNNLNRDDTGSPKDAFFGGYRRARVSSQAQKRAVRTAFKEQLLLSDAERAVRTKRLVEELVRRFPGVEEDKVRLAVENALNALGFGVKEGKTEYLLFLGNRELDRLAELIRDNLDALAVEKGKGKGKTGVSGELKKSLERVLDGGKAVDLALFGRMLADRPDLGVDAAAQVAHALSTHKVDREFDFYTAVDDLNPKEDTGAGMMGDVEFYSATLYRYAVVNLEQLLENLQGDKELAVKGARAFLEAFALTLPSGKQNSFAAHNLPLFIAFRAGEGLPRNLATAFEKPLRPRPDKALSTLSVEALLEEWEKFDSVYGPLFPEEKGAINLTEARLNNTLPELKDMQDLKARVEAALRLLLEG
>NC_015387.1|WP_013703770.1|955452_955959_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MKETAKRFVAYLEALKGQKAWTRARAALRRSLAFDPGAYPPAMPYVEPFVREEGWRREAHYLVAALYALKDGDHQEGRTLARALRGKAQDSASIERRFLALLDADRDQITHRLRQAVGLVEGGLDFALLLNDLIYWFYPEKTVQARWAREFFGTPSEGSGTEATEVTK
>NC_015387.1|WP_083804443.1|953986_955456_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MEKFNLLEESWIPVLKRGTVTEIGLAEALVQAHSIERIETPSPLEEAALHRLLLSVLHRALGGPRDVDGALDLLESGVFSKEKLEAYLDRYHKRFYLFHQQTPFLQIADLPEDPPPVPWVKLRPDLASGNNPTLFDHTTEASFPTASYGEAARALLVHQTFTTGGLLKRFKVTSAKGGPLAGAAAFLSTGKNLFETLLLNLVPYAPEDDFPVWEASPLRRTDVEGYQTAWPLSGTTRVYTWPARGVRLLDEGSGVRFMAYGPGVKPGEAYFRDPMVAYRQDKKGQMLPLRLSTERSFWRDFGAMLPAAGGAWPATLAHAEALLREQSLYFRDSIRHGLRVLGQVADQAKILDVRREVYPLPPGLLEATALSDLEVGLKRAEALGQGLRSLAWTVARGMLGEKDSKELSNFAASLPLERIFWAHLDGAFPGFMARLGQSGALKGWNESLARAALEAWEATRLFVGTGGRHLKALAEGEKRLGGLLREVRA
>NC_015387.1|WP_013703768.1|949825_952600_+|CRISPR-associated-helicase/endonuclease-Cas3
MQLKEAALTLWAKSGEPPHPLLAHMLDAAAVALAILKREPGRTRKLYARDWGLPEEEALRFVAFLVGLHDLGKASPVFQAAWPEGAEQVKEAGFSWDEERVGQKEFWVAHGVFTEVLSYEFLKAKGLPRRMARRLSWALGAHHGFPAQEAEKKKAGLHLCLETPLWHEARAFLVERLWEAVEVRAPQAREAPPEAVLRVMALTSFADWIASDPNFFPYGRHPLDTSYWEEALSLAHKALNRIGWTSREPLPEKPFQALFPFPPNVLQETTADLLQEAQTPVLLLVEAPMGLGKTEAALYAYHLLQGKVGHRGLYVALPTQATANGFFLRVKEFLEKFKDGILLDLQLQHGAAVLNPQYEALLEKARPTQVYEADSLPEKYFQEAEKAAVVASSWFSAKKRAMLSPHGVGTLDQALLGVLKVKHHFIRLWGLMNRVVILDEVHAYDTYTSGLLKALLRWLRALGSSVVLMTATLPRRKREELLSAWGATREALPPYPRVAAFGKGLLGAKSLSLTLQKSVHLESAPIDVSVLSDTLREKLPGVVGAIVNTVDRAQALYRALGEGERLTLAEILDLLGKGLDKGPWPELRKAREEKGHYVVGKRLQDGTLIFLLHARFPAEERALREGIALALFGKHGPRPQKAVLVATQVAEQSLDLDFDLLYTDLAPMDLLFQRAGRLWRHERARPENHPEPVLMVGGIDQGPEFGRDLHWNRVYEDYVLLSTWLSLQERKALAVPQGLEVLLEEVYERTPDVFPVELRKRAEESFAALMERWAQEAKIAENLALSDLEMLFSQTDTAALAAEFRLDDEAEDERTQRFLTRLGDPSVPVVPLYRIGEGWFMDPQGKCRIKLKGDLTKEEALALWGRAVRLSRTPIPQILLKEEPPPAWRKSGLLRNLRPLEVGRDFGRIRVDLDPELGITYFTG
>NC_015387.1|WP_013703767.1|948847_949816_+|WYL-domain-containing-protein
MPQVTKTQRLMSMLEALKLRPMRVSDLARRYGVSERTVERDLMALATLGHEVERVGRGLYRVKDRPSALQPVEALALFAAGRLIYHQAPTRQYKSALEKLARTLPEPLRTLLLRSTEGLESRRGDSRTLEMVARALLEKRVLAFEYRSGGSKNWRPKELLVYFLEANRTNLSLYAIGYERSYHKKVLTFKLSRMRNTRLLEETYEIPGDFDPNEYLHQAWGVVGVKEKAVEVCLRFAPEAAWRVLEGEYPGLEVEEKFPDGSLQARILAAPFKGGVPWEVLAWVQSFGPRVEVLSPPELRALWLEEARQVLAKASEPVGKQG
>NC_015387.1|WP_013703766.1|948148_948685_-|DUF2179-domain-containing-protein
MEALLGALLIFALRVTDVTIGTLRLLYMVRGARTVAAGLGFLESLIWITATTQVFRHLDNLWNLFGYALGFAAGIAFGITVEGWIAAGYILVRIIHKEAPHELVRALREQKFGVTLVRGEGRDGAVWILFVVAPRRRGQVLLEAVQTLAPQAFVTIESVTQAIGGYLPRLAPAHTVRK
>NC_015387.1|WP_013703777.1|963380_965264_+|aminodeoxychorismate-components-I/II
MEALGLYRRARALGLRPALLESLGPRTAFGRRTLLGLRPTRRLEVWGGVLYEDGRLVGTALDLLERLEEGLGEGHFPAWIGFFAYEFARHLGLPARAPMPGLPEAAFCYYPEGYVWEDGRLVEAPSVLLEVDPGMPVGLPEVRLVSDYPREAFIAGVQAVQERIRAGWVYQVNLSHRFRFPAVGLDPLDYYAALRRTNPSPFMGLVEGAGWAVVSGSPERLFALREGVLSARPIAGTRRRGRTPEEDQALEAELRANVKERAEHVMLVDLLRNDLSRVAEPGTVEVSEAFTVERYSHVMHLVSEVRGVSRAGVGAALRAIFPGGTITGAPKESVMQAIAELEPVPRGAYTGSLGYVSGRGADFNILIRSLTLAGGWAYLSAGAGIVIESDPVREYEETRHKAEALLYVLGQGRPGVRPEPPRVIEAWRPPRPRRRYAARVVFLENHDSFSYNLVNYLRMLGAEVRVVDHGEPPALGGATHLVVGPGPGDPFTAGRTLEWVRAALEDGVPFLGVCLGHQALGVALGAVLERAPRPVHGEAHPVRHVGRGVFAGLPDPAPFTRYHSLHLRDLPPVLERLAWTEDGVVMGVGHRSRPAWGVQFHPESMLSPYGLELLANFLEVRGAAGDR
>NC_015387.1|WP_041658284.1|965250_965985_+|aminotransferase-class-IV
MVIVNGEPAAAAWPVAFVYHGASVFTTLRSEGGEPLWWGRHLDRLRRHAEALGLPYPGHAAFERAWELLRVQGPDLRVRLTVGEGVWCAEASPYRPLEPGVYLEGVRVHVSRWRVHPDLARYKTGNYLPYRLALAEARAAGAFEALLLDGEGCVVDGSRTSPLLYRDGVLTVFEGGLEGITREVVAEAAREMGLGVRRARLAPGALAGQLLLAGSGVGLVPVGAVRDAEVRALVERFRPGGGPR
>NC_015387.1|WP_013703779.1|966361_967510_+|homoserine-O-acetyltransferase
MTGTVVCEAWGEHEALLLHPVTDASDAATVRPRTAVLWPRTAPFVTEEGRLIPEVRVRFETYGRLSAQRDNAVLVFHALTGSAHLAGTYDAATLARLTPLERAFGPKGWWDALVGAGRPLDPERYFVVCANILGSCYGTTGPTSRNPTTGRRYGPEFPPITIRDMVRVQARLLDHLGVERALVIGGSMGGMQALEFALMYPERTAGLVVIAATERYGPWARAFNRVAREAILNDPAFRNGRYEAQPPGLAVARAVAMMSYRAPRSFEARWGADPSQSERYIAYQAQRFLRRFDANTYLTLSHAMTTHDVTRGRGALPEVLERLAMPRLFVGIDSDLLYPAPAVRALAQAARGEYAELVSPHGHDAFLIEHDQVAAVLKAFGV
>NC_015387.1|WP_013703780.1|967490_967982_-|hypothetical-protein
MRALLLTLLLLGTLAQAHGGHLELENARILVRDTEAFLEARLVYGEEEPLALTAVVLQGVEGVLEERQTQGYAPLSRIEIQPGTLEFGPETPVRVRFEIAGLELKGPTVPVTLLITPGGLVTQAVPLDTGTASVRPSLGVLLAVLLALWVLLGRYRRAKPQRP
>NC_015387.1|WP_013703781.1|967993_968584_-|SCO-family-protein
MRWRIALLVAGVLAIAGYAAYKALSPKPTFHGTMLSTPRPVPDFTLIDGDGRPRRFSAFRGKTLLVFFGYTRCPDVCPLTMQKLALAYRALGEPEDLQVVMISVDPETDTPERIQQYVTGFHPRFVGLTGTPEAIAQAASAFFIYYRARDQLVDHTATINLVDPQGRLRVVYNEANLAPQTLAEDLKPILARGGRF
>NC_015387.1|WP_013703782.1|968589_970620_-|NAD-dependent-DNA-ligase-LigA
MTREEAKKRVLELRQAIRYHNYRYYVLDDPEISDAEYDALMRELKALEARYPDLVTPDSPTQVVGAGMIESSFREIQHPTPLYSLDNAFNLEEVREFEARLERALGRPGPFEYTVEYKIDGLSVNLYYEEGFLVWGATRGNGRTGEEVTQNLLTIPDVPRRLEGAPARLEVRGEVYMPRDTFLKLNQAREEAGLPPFKNPRNAAAGSLRQQDPRVTATRGLRAYFYGIGLGLQETGVETQAELLDYLKRAGFPVEPHARVVRGVEGIETAYQAFLAQRHTVPFEADGVVVKLNNLAWQDELGYTAKSPRWAVAYKFPAEEKKTRVLEVIFQVGRTGRVTPVAVLEPVLLDGTTVSRVSLHNEAYLEELGLMLGDWVLVHKAGGIIPEVLRVLKEERTGTERPLVFPDACPACGHALVLEGKIHRCPNPLCPAQAFERIRHYASRRAMDIQGLGERHIEQMLEKGLIRTPADLYRLTKADLVSLERFGEKSAENLLAQIEASKTRGLERLLFALGIPQVGEALARTLARRFGTLDRLLEATPEELLEVEDVGELTARRIHETLHDPAMLELIEQLRAAGVSFEAKERPRSDALAGLTFVLTGELSRPRAEVKRRLEALGAKVASAVSKKTSYVVAGAGAGSKLQKARELGIPVLDEAGLEALIQQRLGQMSQAGALE
>NC_015387.1|WP_013703783.1|970708_971833_+|BMP-family-ABC-transporter-substrate-binding-protein
MKRLLLVSAMLATLLGMGSAQKLIGIAFDAGGKNDRSFNESTWKGAQRAEKDFDIQLFDFEPADPSQVGQGIRAFAEEGFDLIIGVGFANEPAITANAREFKDVNFAVIDAVPGEGKLENAVGLVFREHEGSFLVGYIAGKLTQTGVVGFIGGMDIPLIHKFEQGYKAGVEYACQEDGIECTVLINYVGNTPAAWNDPAKAKEIAINQKAQGADIIYHAAGGSGLGLIDFVKQEMCIKASDLPAGVEFIRDPFADVPKYPAYEQKCGEDARPLFFIGVDANQNFLGDTDNNPETLNHGLTSMLKRVDVATYEVIESVVNDAFQGGVREFGLENDGVGYALDEYNRALIPAAVVEALDRIKQDIIAGRIEVPASR
>NC_015387.1|WP_013703784.1|971891_973409_+|ABC-transporter-ATP-binding-protein
MSEYALELRGITKQYPLVLANDDIHLGVRWGEVLALVGENGAGKSTLMKIVYGLVEPDRGEIYVDGKRAEIRGPADAIALGIGMVHQHFMLVDPLSVVDNVILGSEPVQGVSIDYRKARAEVVRLIEELGFDLDPDARIEELPVGLQQRVEILKTLYRKARILILDEPTAVLTPQEAAELFRFLRRYVAQGNAAIIITHKLDEVMEVSDRVTVIRDGRVVGTVATQETSPPELARMMVGREVILTVEKRPKTPGEVVLEVQDLRVAEAGKKPRLDGVSFQVRAGEIVGIAGVEGNGQTELVEAVTGLRPYSGTVRYGGEILARPDARRVREWGVSHIPEDRNARGLVLDFPTRDNVILGDHYKPPFVGAFGFFVDEAVNRYAQEVVEAFDVRPRSIHLSARRYSGGNAQKIIVGRELARRPRLLVAAQPTRGVDIGAIEFIHRRIVEARDAGMAVLLVSADLNEVMSLSDRILVMYEGRIVGEVRPGEVTEEELGLMMAGMRANA
>NC_015387.1|WP_148230459.1|973548_974817_+|DUF3179-domain-containing-protein
MYVTVFLGLLFGGAAVGQSFNFVVLEVDADTANIPVNEVISGGPPPQGIPALGFTGSFNGRVPPTPAPKFIAAEAASAWLEPQEPVLAFGMNGEAKAYPLQILMWHEIANDVVGGVPVAVTFCPLCNSAFAYDRRVPLTQAQLEAVRAKNPNAPLVEPDAAYLEAYADEVGEEAAAQVVAALEVTFGTSGMLFNSNLVMFDSATSTLWAQLAAEGNVGTLTGVKLLRYPVQIVSFAEFREAFPEGVVLSRETGFSRRYGQNPYVGYDRVDQPPFLFSGPTDGRLPPKLRVVSLELGGEPVAYPFSVLEEVRVVNDAVGGVPIVVMWREGTTSALDRSSISGSKDVGAVAVFRRELDGRVLTFEWNGEAFVDQQTGSTWNLFGAATSGPLEGQRLEPVIHDNTLWFAWAAFKPETRVYGISTE
>NC_015387.1|WP_013703786.1|974819_975188_+|DUF393-domain-containing-protein
MKRALLVYDGGCGFCVRWARRWMRWDRARRLEIVAFQAPGVLERAGIGLSAAREAVWLVEEGRCYRGAAAVFRTLDLALGVPVFYAVYRLPGLGRVADGVYGWVAAHRHRFGGAGCGSHGLP

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Crispr_ID: NC_015387_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_7

1465974-1467823

Orphan

Consensus_repeat	Method
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CRISPRCasFinder
TTTCAAATCCCAGAAGGAACGGTGAAAAC	PILER-CR
TTTCAAATCCCAGAAGGAACGGTGAAAACC	CRT

27 spacers

The CRISPR arrays of NC_015387_7

>merge|NC_015387|7|1465974-1467823|CRISPRCasFinder,PILER-CR,CRT
ATTTCAAATCCCAGAAGGAACGGTGAAAACGAGACACGCGGGGTGTTTGTTCTATACTCGAGGTGTCCCGTTTCAAATCCCAGAAGGAACGGTGAAAACAGAGTTCGCGAAAGCGGTCCTTGAAGAGCTCGAGGAGTTTCAAATCCCAGAAGGAACGGTGAAAACCTCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAAGTTTCAAATCCCAGAAGGAACGGTGAAAACCTCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAAGTTTCAAATCCCAGAAGGAACGGTGAAAACCCCGGAAATGCTGATCACGAGCAGGCGGCACCCCGTCACGTTTCAAATCCCAGAAGGAACGGTGAAAACCTGCACAAGGGCATGGCAGGGGGGGCGGACGTATTGGCGTTTCAAATCCCAGAAGGAACGGTGAAAACCGCGGCCAGCGCCTCGCCGACGCCGAGCATGTCCAGGAGTTTCAAATCCCAGAAGGAACGGTGAAAACCTGCCCGCAACGGGTTCCAACCTCCGCGCCGCCGCTTCATGTTTCAAATCCCAGAAGGAACGGTGAAAACCCGGGCGCGGCGTGAGGCGGATATGTGGGCCAGGGAGGTTTCAAATCCCAGAAGGAACGGTGAAAACCTGCGGATCGTGATCGGTGTGGGCTACGTGGGAGCGGGTTTCAAATCCCAGAAGGAACGGTGAAAACCCCCGAGAGCCCGAGCCCGTTCCAGCGCTTCATTGACGTTTCAAATCCCAGAAGGAACGGTGAAAACCGAAAGAACTCCCGCTCCCGGAACTCCGGGAGCGATATTTCAAATCCCAGAAGGAACGGTGAAAACCGGTTTTCCGGTTAGGGGTTGTTCCTGTGTTTGGATGTTTCAAATCCCAGAAGGAACGGTGAAAACTAGTAACTCCAGGATCACATACCACGGAATGATTCGTTTCAAATCCCAGAAGGAACGGTGAAAACCTCCGTGCTATCTCTGTTTTTGGCCTCCCCTCCCCTGTTTCAAATCCCAGAAGGAACGGTGAAAACCCCCCCGCCCAATCCGGATCACGAAACTGCACTCGGGATTTCAAATCCCAGAAGGAACGGTGAAAACCGTGCTCGACAACCTAGCCAAAGCCTACGGGGTAGCGGTTTCAAATCCCAGAAGGAACGGTGAAAACCTTCATCTTGTCCCCCCTACGGCGTTCTTGAGGTTTACTTTCAAATCCCAGAAGGAACGGTGAAAACCGGGCCGCCTGAGGGTAGGCCTCCTCAATGATCTCGTCGAGTTTCAAATCCCAGAAGGAACGGTGAAAACCTGTTTCAGTTTGTATACCCCCCGGAAAAATGATGAGGTTTCAAATCCCAGAAGGAACGGTGAAAACCGACGCGATGCGCCCCAGGAGTTCACCGGCTTTTTCGCTTTCAAATCCCAGAAGGAACGGTGAAAACCCGGAACGCGCGCGCGACGCCTGAGCCCCGAGGAGCGCTTTCAAATCCCAGAAGGAACGGTGAAAACCGCTTGGTCTATTTATTCATCCGTGGGGGCCAGGACGATTTCAAATCCCAGAAGGAACGGTGAAAACCTGCAGAAGACCTGATGGAGCGGCTCGGCCGCCTGAATTTCAAATCCCAGAAGGAACGGTGAAAACCAGGAGGTTTGAGGTGGCCCAGGATCTGGAGAAACTCTATTTCAAATCCCAGAAGGAACGGTGAAAACCCAAACCCAGACGACGGGAGTGGTGCACGTGGAAAAGTTTCAAATCCCAGAAGGAACGGTGAAAACCGGGGACGTCATCGAGATCCGCAGGGGCGGCAGCTGGAATTTCAAATCCCAGAAGGAACGGTGAAAACC

>NC_015387|7|7|1465974-1467822|CRISPRCasFinder
ATTTCAAATCCCAGAAGGAACGGTGAAAAC	GAGACACGCGGGGTGTTTGTTCTATACTCGAGGTGTCCC
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	AGAGTTCGCGAAAGCGGTCCTTGAAGAGCTCGAGGA
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAA
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAA
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CCCGGAAATGCTGATCACGAGCAGGCGGCACCCCGTCAC
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCACAAGGGCATGGCAGGGGGGGCGGACGTATTGGC
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CGCGGCCAGCGCCTCGCCGACGCCGAGCATGTCCAGGA
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCCCGCAACGGGTTCCAACCTCCGCGCCGCCGCTTCAT
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CCGGGCGCGGCGTGAGGCGGATATGTGGGCCAGGGAG
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCGGATCGTGATCGGTGTGGGCTACGTGGGAGCGG
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CCCCGAGAGCCCGAGCCCGTTCCAGCGCTTCATTGAC
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CGAAAGAACTCCCGCTCCCGGAACTCCGGGAGCGAT
ATTTCAAATCCCAGAAGGAACGGTGAAAAC	CGGTTTTCCGGTTAGGGGTTGTTCCTGTGTTTGGAT
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	TAGTAACTCCAGGATCACATACCACGGAATGATTC
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTCCGTGCTATCTCTGTTTTTGGCCTCCCCTCCCCT
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CCCCCCGCCCAATCCGGATCACGAAACTGCACTCGGG
ATTTCAAATCCCAGAAGGAACGGTGAAAAC	CGTGCTCGACAACCTAGCCAAAGCCTACGGGGTAGCG
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTTCATCTTGTCCCCCCTACGGCGTTCTTGAGGTTTA
CTTTCAAATCCCAGAAGGAACGGTGAAAAC	CGGGCCGCCTGAGGGTAGGCCTCCTCAATGATCTCGTCGA
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGTTTCAGTTTGTATACCCCCCGGAAAAATGATGAG
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CGACGCGATGCGCCCCAGGAGTTCACCGGCTTTTTCG
CTTTCAAATCCCAGAAGGAACGGTGAAAAC	CCGGAACGCGCGCGCGACGCCTGAGCCCCGAGGAGCG
CTTTCAAATCCCAGAAGGAACGGTGAAAAC	CGCTTGGTCTATTTATTCATCCGTGGGGGCCAGGACG
ATTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCAGAAGACCTGATGGAGCGGCTCGGCCGCCTGA
ATTTCAAATCCCAGAAGGAACGGTGAAAAC	CAGGAGGTTTGAGGTGGCCCAGGATCTGGAGAAACTCT
ATTTCAAATCCCAGAAGGAACGGTGAAAAC	CCAAACCCAGACGACGGGAGTGGTGCACGTGGAAAA
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	CGGGGACGTCATCGAGATCCGCAGGGGCGGCAGCTGGA
ATTTCAAATCCCAGAAGGAACGGTGAAAAC

>NC_015387|7|4|1465975-1467822|PILER-CR
TTTCAAATCCCAGAAGGAACGGTGAAAAC	GAGACACGCGGGGTGTTTGTTCTATACTCGAGGTGTCCCG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	AGAGTTCGCGAAAGCGGTCCTTGAAGAGCTCGAGGAG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAAG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAAG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CCCGGAAATGCTGATCACGAGCAGGCGGCACCCCGTCACG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCACAAGGGCATGGCAGGGGGGGCGGACGTATTGGCG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGCGGCCAGCGCCTCGCCGACGCCGAGCATGTCCAGGAG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCCCGCAACGGGTTCCAACCTCCGCGCCGCCGCTTCATG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CCGGGCGCGGCGTGAGGCGGATATGTGGGCCAGGGAGG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCGGATCGTGATCGGTGTGGGCTACGTGGGAGCGGG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CCCCGAGAGCCCGAGCCCGTTCCAGCGCTTCATTGACG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGAAAGAACTCCCGCTCCCGGAACTCCGGGAGCGATA
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGGTTTTCCGGTTAGGGGTTGTTCCTGTGTTTGGATG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	TAGTAACTCCAGGATCACATACCACGGAATGATTCG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTCCGTGCTATCTCTGTTTTTGGCCTCCCCTCCCCTG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CCCCCCGCCCAATCCGGATCACGAAACTGCACTCGGGA
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGTGCTCGACAACCTAGCCAAAGCCTACGGGGTAGCGG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTTCATCTTGTCCCCCCTACGGCGTTCTTGAGGTTTAC
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGGGCCGCCTGAGGGTAGGCCTCCTCAATGATCTCGTCGAG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGTTTCAGTTTGTATACCCCCCGGAAAAATGATGAGG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGACGCGATGCGCCCCAGGAGTTCACCGGCTTTTTCGC
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CCGGAACGCGCGCGCGACGCCTGAGCCCCGAGGAGCGC
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGCTTGGTCTATTTATTCATCCGTGGGGGCCAGGACGA
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CTGCAGAAGACCTGATGGAGCGGCTCGGCCGCCTGAA
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CAGGAGGTTTGAGGTGGCCCAGGATCTGGAGAAACTCTA
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CCAAACCCAGACGACGGGAGTGGTGCACGTGGAAAAG
TTTCAAATCCCAGAAGGAACGGTGAAAAC	CGGGGACGTCATCGAGATCCGCAGGGGCGGCAGCTGGAA
TTTCAAATCCCAGAAGGAACGGTGAAAAC

>NC_015387|7|3|1465975-1467823|CRT
TTTCAAATCCCAGAAGGAACGGTGAAAACG	AGACACGCGGGGTGTTTGTTCTATACTCGAGGTGTCCCG
TTTCAAATCCCAGAAGGAACGGTGAAAACA	GAGTTCGCGAAAGCGGTCCTTGAAGAGCTCGAGGAG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAAG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TCCTTAGCGCGGTGAGCGGTGAGCGCCCCCCGCGCGAAG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	CCGGAAATGCTGATCACGAGCAGGCGGCACCCCGTCACG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TGCACAAGGGCATGGCAGGGGGGGCGGACGTATTGGCG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GCGGCCAGCGCCTCGCCGACGCCGAGCATGTCCAGGAG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TGCCCGCAACGGGTTCCAACCTCCGCGCCGCCGCTTCATG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	CGGGCGCGGCGTGAGGCGGATATGTGGGCCAGGGAGG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TGCGGATCGTGATCGGTGTGGGCTACGTGGGAGCGGG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	CCCGAGAGCCCGAGCCCGTTCCAGCGCTTCATTGACG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GAAAGAACTCCCGCTCCCGGAACTCCGGGAGCGATA
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GGTTTTCCGGTTAGGGGTTGTTCCTGTGTTTGGATG
TTTCAAATCCCAGAAGGAACGGTGAAAACT	AGTAACTCCAGGATCACATACCACGGAATGATTCG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TCCGTGCTATCTCTGTTTTTGGCCTCCCCTCCCCTG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	CCCCCGCCCAATCCGGATCACGAAACTGCACTCGGGA
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GTGCTCGACAACCTAGCCAAAGCCTACGGGGTAGCGG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TTCATCTTGTCCCCCCTACGGCGTTCTTGAGGTTTAC
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GGGCCGCCTGAGGGTAGGCCTCCTCAATGATCTCGTCGAG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TGTTTCAGTTTGTATACCCCCCGGAAAAATGATGAGG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GACGCGATGCGCCCCAGGAGTTCACCGGCTTTTTCGC
TTTCAAATCCCAGAAGGAACGGTGAAAACC	CGGAACGCGCGCGCGACGCCTGAGCCCCGAGGAGCGC
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GCTTGGTCTATTTATTCATCCGTGGGGGCCAGGACGA
TTTCAAATCCCAGAAGGAACGGTGAAAACC	TGCAGAAGACCTGATGGAGCGGCTCGGCCGCCTGAA
TTTCAAATCCCAGAAGGAACGGTGAAAACC	AGGAGGTTTGAGGTGGCCCAGGATCTGGAGAAACTCTA
TTTCAAATCCCAGAAGGAACGGTGAAAACC	CAAACCCAGACGACGGGAGTGGTGCACGTGGAAAAG
TTTCAAATCCCAGAAGGAACGGTGAAAACC	GGGGACGTCATCGAGATCCGCAGGGGCGGCAGCTGGAA
TTTCAAATCCCAGAAGGAACGGTGAAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013704246.1\|1479439_1479718_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704238.1\|1468511_1469264_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277331
NC_015387.1\|WP_013704234.1\|1462987_1463578_+\|FtsQ-type-POTRA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224505
NC_015387.1\|WP_013704231.1\|1459762_1460803_+\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|234825
NC_015387.1\|WP_013704235.1\|1463574_1464822_+\|cell-division-protein-FtsA	unknown	unknown	gnl\|CDD\|223918
NC_015387.1\|WP_013704245.1\|1478618_1479383_-\|LPS-export-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213185
NC_015387.1\|WP_013704241.1\|1473415_1474537_+\|methyltransferase	unknown	unknown	gnl\|CDD\|368316
NC_015387.1\|WP_013704229.1\|1457451_1458720_+\|UDP-N-acetylmuramoylalanine--D-glutamate-ligase	unknown	unknown	gnl\|CDD\|273436
NC_015387.1\|WP_013704230.1\|1458698_1459766_+\|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl\|CDD\|274033
NC_015387.1\|WP_013704243.1\|1476258_1477158_+\|delta(1)-pyrroline-2-carboxylate-reductase-family-protein	unknown	unknown	gnl\|CDD\|235996
NC_015387.1\|WP_041658335.1\|1456597_1457455_+\|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl\|CDD\|133462
NC_015387.1\|WP_013704236.1\|1464831_1465902_+\|cell-division-protein-FtsZ	unknown	unknown	gnl\|CDD\|236468
NC_015387.1\|WP_013704239.1\|1469286_1472304_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NC_015387.1\|WP_013704233.1\|1462154_1462991_+\|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl\|CDD\|237776
NC_015387.1\|WP_013704232.1\|1460799_1462158_+\|UDP-N-acetylmuramate--L-alanine-ligase	unknown	unknown	gnl\|CDD\|234757
NC_015387.1\|WP_013704242.1\|1474592_1476026_+\|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl\|CDD\|235640
NC_015387.1\|WP_013704240.1\|1472348_1473344_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl\|CDD\|236585
NC_015387.1\|WP_013704227.1\|1455851_1456595_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704237.1\|1468076_1468445_-\|response-regulator	unknown	unknown	gnl\|CDD\|333815
NC_015387.1\|WP_013704244.1\|1477145_1478609_-\|DUF3084-domain-containing-protein	unknown	unknown	gnl\|CDD\|378623

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013704238.1\|1468511_1469264_-\|metallophosphoesterase	gnl\|CDD\|277331	cd07385, MPP_YkuE_C, Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain. YkuE is an uncharacterized Bacillus subtilis protein with a C-terminal metallophosphatase domain and an N-terminal twin-arginine (RR) motif. An RR-signal peptide derived from the Bacillus subtilis YkuE protein can direct Tat-dependent secretion of agarase in Streptomyces lividans. This is an indication that YkuE is transported by the Bacillus subtilis Tat (Twin-arginine translocation) pathway machinery. YkuE belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	6.37474e-61
NC_015387.1\|WP_013704234.1\|1462987_1463578_+\|FtsQ-type-POTRA-domain-containing-protein	gnl\|CDD\|224505	COG1589, FtsQ, Cell division septal protein [Cell envelope biogenesis, outer membrane].	9.59627e-13
NC_015387.1\|WP_013704231.1\|1459762_1460803_+\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|234825	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional.	4.53187e-115
NC_015387.1\|WP_013704235.1\|1463574_1464822_+\|cell-division-protein-FtsA	gnl\|CDD\|223918	COG0849, ftsA, Cell division ATPase FtsA [Cell division and chromosome partitioning].	8.84298e-149
NC_015387.1\|WP_013704245.1\|1478618_1479383_-\|LPS-export-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213185	cd03218, ABC_YhbG, ATP-binding cassette component of YhbG transport system. The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.	4.29522e-138
NC_015387.1\|WP_013704241.1\|1473415_1474537_+\|methyltransferase	gnl\|CDD\|368316	pfam05175, MTS, Methyltransferase small domain. This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.	2.2697e-60
NC_015387.1\|WP_013704229.1\|1457451_1458720_+\|UDP-N-acetylmuramoylalanine--D-glutamate-ligase	gnl\|CDD\|273436	TIGR01087, UDP-N-acetylmuramoylalanine--D-glutamate_ligase, UDP-N-acetylmuramoylalanine--D-glutamate ligase. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	1.37891e-117
NC_015387.1\|WP_013704230.1\|1458698_1459766_+\|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl\|CDD\|274033	TIGR02210, Rod_shape-determining_protein_RodA, rod shape-determining protein RodA. This protein is a member of the FtsW/RodA/SpoVE family (pfam01098). It is found only in species with rod (or spiral) shapes. In many species, mutation of rodA has been shown to correlate with loss of the normal rod shape. Note that RodA homologs are found, scoring below the cutoffs for this model, in a number of both rod-shaped and coccoid bacteria, including four proteins in Bacillus anthracis, for example. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	2.75937e-73
NC_015387.1\|WP_013704243.1\|1476258_1477158_+\|delta(1)-pyrroline-2-carboxylate-reductase-family-protein	gnl\|CDD\|235996	PRK07340, PRK07340, delta(1)-pyrroline-2-carboxylate reductase family protein.	2.63529e-129
NC_015387.1\|WP_041658335.1\|1456597_1457455_+\|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl\|CDD\|133462	cd06852, GT_MraY, Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate. It is an integral membrane protein with possibly ten transmembrane domains.	3.68839e-82
NC_015387.1\|WP_013704236.1\|1464831_1465902_+\|cell-division-protein-FtsZ	gnl\|CDD\|236468	PRK09330, PRK09330, cell division protein FtsZ; Validated.	0
NC_015387.1\|WP_013704239.1\|1469286_1472304_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NC_015387.1\|WP_013704233.1\|1462154_1462991_+\|UDP-N-acetylmuramate-dehydrogenase	gnl\|CDD\|237776	PRK14651, PRK14651, UDP-N-acetylmuramate dehydrogenase.	9.44062e-149
NC_015387.1\|WP_013704232.1\|1460799_1462158_+\|UDP-N-acetylmuramate--L-alanine-ligase	gnl\|CDD\|234757	PRK00421, murC, UDP-N-acetylmuramate--L-alanine ligase; Provisional.	1.47795e-175
NC_015387.1\|WP_013704242.1\|1474592_1476026_+\|RNA-polymerase-sigma-factor-RpoD	gnl\|CDD\|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	2.41063e-159
NC_015387.1\|WP_013704240.1\|1472348_1473344_-\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl\|CDD\|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	4.93932e-176
NC_015387.1\|WP_013704237.1\|1468076_1468445_-\|response-regulator	gnl\|CDD\|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	1.84345e-28
NC_015387.1\|WP_013704244.1\|1477145_1478609_-\|DUF3084-domain-containing-protein	gnl\|CDD\|378623	pfam11283, DUF3084, Protein of unknown function (DUF3084). This bacterial family of proteins has no known function.	2.43066e-28

>NC_015387.1|WP_013704236.1|1464831_1465902_+|cell-division-protein-FtsZ
MEGAVIKVIGLGGAGNNAVNRMIESGLSGVEFIAANTDAQVLARSLADIRIQIGDKLTRGLGAGANPEIGERAAEENRDLIAEHLEGADLVFITAGMGGGTGTGSAPVVAEIARDLGALTIAVVTRPFSFEGPKRLRVAEEGIKKLKDRVDAMVVVNNDRLLSAVDKKMTLKDAFLIADRVLYHGVKGITDVINLPGLINVDFADVRTMLSGAGQVLMGIGAGRGENRVAQAAQSAISSPLLDRTIEGARRLLVNVVGSEELSLMEASEVVEHVREATGFEDVDILYGVTYDERAADELRVILIAAGFNEPQVSVYPSDTSRIMDFAPQGTIDPTNYEIPAFIRYGDGDYPPKRGN
>NC_015387.1|WP_013704235.1|1463574_1464822_+|cell-division-protein-FtsA
MSERIIVGLDVGTTKVCTVIGELASDGVLDIIGEGTVPSQGLKRGVVVNLERTTEAIRASVRAAERVAGVPAERVYVGVAGAHIRSVTSHGLAAIRRGHSITPADVERAIEQAKAFPFEGDHELIHALPLEYRVDGQEGIRDPVGMAGVRLEVDVHLVAGGKGPLANLRRAVEAAGLGVQGLVLQSYASGLSVLSPEELGMTVMLVDIGGGTTDVAVFRGGRLAHSAVVPLGGDHITGDIAQLLKIPFEEAERVKKKYGAALPELADPDLVLEINHEGNPMGGIPAPELARIIRPRVREILHLARSSVDEVLGPLEVSVSKVVLTGGAALMRGIEELARKQYNLPVRLGRPGGISGLTDVVSSPAHATAVGLVRFGALEDTVAGEAPLPTRPKRSRDTQETNLWERIKGIFKDFF
>NC_015387.1|WP_013704234.1|1462987_1463578_+|FtsQ-type-POTRA-domain-containing-protein
MSRLLVAVLALATAYVASLVVLPIEKVEVVGTAHLTKPEVQRLTGLYPGESWLWATSFKLRALRADPWVKAARIERPALGVVRVVVTERVPVATLVRGKEERLGLAGDGTVLPGAPRVGPEIQGFGPDRTREALEIVRLFPDATSIHYTPAGFSVNWQGRKLWAPDARSLRAVADRARMSASTEYYAYTWGVSLRR
>NC_015387.1|WP_013704233.1|1462154_1462991_+|UDP-N-acetylmuramate-dehydrogenase
MRVETVQLKGYTTLGVGGPAELWTVETPEDLKEAAQAPYRVLGNGSNLLVSDQGVPERVIKLGGVFTAWDLNLTPRNGAYITGWIGAGAMLPLLVQEAARKGLSGLEGLLGIPATVGGAVRMNAGTRYGEIADALEVVEVFHDGQLRHYRPEELGFAYRTSHLPPGGIVTRVRFRLTPSTPKAVREKMALVDQARKGQPKKKSAGCAFKNPPGDSAGRLIDVHGLKGLREGQAMVSLEHGNFIVNLGGATARDVWRLVQRIRSVIPLELEWEVWGVIE
>NC_015387.1|WP_013704232.1|1460799_1462158_+|UDP-N-acetylmuramate--L-alanine-ligase
MKHYHFMGISGVSMSALAWLLLRNGHRVTGCDLAPSELAYRLEGDGALILRGHSPDHLEGVDVLVASTAIPDHHPELAAARARGIPVLRRIELLGEILARGRSIGVTGTHGKTTTTSMLGAAFIRAGKDPMVLVGGEVADLGGNARYGEGPYRIAEVDESDPLFQHLQVNTALLTNLEDDHVAAPGQTRQNYHESFEALIQATRRFAQRAGHVVYNADWPLLEEVTAGLERVGFGLEHGAFRAEAVDLSPEGSRFRVVWDGTVLGEARLRVLGLHNVMNALGVIAVSALEGLDLEAVFAALAEFRGAHRRFERVGEINGAWVVDDYAHHPTEVAATLQAARATGRRVRVVFQPHRYLRTLQMWERFAEALQLADEAVVLEVYAAGEAPIEGVSGRLIAERLQALGHPARFMEWDEAQAYLTESARANDLILTMGAGDVWRLGVELARTGEGA
>NC_015387.1|WP_013704231.1|1459762_1460803_+|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase
MRFVVTGGGTGGHIFPAIAVGARLAELGHEVHYVGSRTGLEARLVPKHGLRFHGLTAGKFDRTAFRPGEAFKVIRGLLEARSLLRELRPDAVLATGGYAAFPFAFVAARAGVPLVVHEQNARMGLANRWLAPHARRLALAMPIPSAPAKAEVVGLPVREVRHDPQEARHALGLEPDRPTLLVLGGSQGSKVLNEALPGLLEPYLETWQVLHQTGERWLEETQGRVRHPHYHLAGFVDTTLAWAAAEIAITRAGAMTLAEAAYHRVPLLLVPLPPEIDSGAQRANARLYQERGAARMLDQGNWERFHDALAPLLDPARRAEMRRALATLSPEGAADRTARLVLEVVR
>NC_015387.1|WP_013704230.1|1458698_1459766_+|FtsW/RodA/SpoVE-family-cell-cycle-protein
MDPLLALAQLLLVGFSLLGVVTAAPELFQEHALRIGVALLVTVAAALVSPKLVVRLARPFYLLVLVLLIAVLIWGEGPEGVRRWLYLGGIAFQPSELMKLAMVAYLASFFDQHGPDYPVIGPILAVGLAVGLIALEPDFSTAVFHLFIAIFLLLVIGVPWRRLIAIGLFTSVLAVSLQGLYLSRFRYVKERFLSFLAQLNQTADPQAEGFQTNQALEAVLQGGLFGQGPGGPMPFVPAGHNDMIFAAIAFSGGWLAAAVLVLTYGLIFARGMQIAAHSHGAVSVLALGLTAVITVQAAINIGVTLGFLPVTGVALPFVSYGGSATVATGIAFGLLHSTARAALRTPPTRKQRRAS
>NC_015387.1|WP_013704229.1|1457451_1458720_+|UDP-N-acetylmuramoylalanine--D-glutamate-ligase
MSTPRLVFGLGRSGLGVLRFLARRGLPARFHDEHPRPQDLEAARALGFLEDPDPKPGAYREVIAAPGVPIDHPLLQRLREGGAEVIGEAELAYRHVPTPLIGVTGTAGKGSTTLFTAHLLRASGLRAVAGGNLDPPLVDVVEDAEVAVVELSSFQLERVVHFAPRVAVLLNLGVDHLDRHRTPEAYHQAKLNLLKNLTDQDALVYNAADPRVRQAAHRTPARLYPFTPGPTPRETNLEAAYWAARAYLEGVGLEVDEARLRAALATAPSLPGRFETFGRVGEVVFIDDSIATRTLAVQAALAAAPAPIAWILGGVSKGAALEDLRPLVARKVRVLLAIGRDGPQMARAFRDLVEVVEISETDGNTALERAIAEALARIQHGSVLLAPLAASFDQFADYKARSRAFREAAQRIGGAAWTPSSP
>NC_015387.1|WP_041658335.1|1456597_1457455_+|phospho-N-acetylmuramoyl-pentapeptide--transferase
MATALALSWFLVGMQVSLMRSLRWGKAVRAEGPKAHLEKAGTSSMGGVAFTLAATLVYLLTPDDGLRSVWLLAMGYGLLGLADDLGGLWGRPLKAREKLPLQFMMAAVFAAYALREVSYTPYPALDFVLIVLAVVGAANALNFTDGLDGLAATVSVVLLLPFSHTILAQSFIGALLGFLWHNAPKAKIFMGDAGSQLLGALIAGVFILEGKLWYLPLAAIVPVLEVLSVVVQVVYFRRTGRRILKMSPLHHHFELSGWEEPKIVFRFAVLTALATALAAGLWGGV
>NC_015387.1|WP_013704227.1|1455851_1456595_+|hypothetical-protein
MRMREGARVILAGLGLALGACAPSLTQPTAPSLLVPGGRIEGGWAVLERLTFPLAGPPLAADRSGGTLYAAYPFQLLAYREGQLVEALPLPGVPRFVRARPALVVGLEQGLFVPERGLLELPAQDAVRREDGVFWVGREGFWRGRARLVQGAFRAVAGNDRFVFALGETAYRFPDGLTFPLPAGWRAAGLAEDLYLLTPEGVVRLSPEGLELDRLEGTFDALAVDASGVWLLAGNRVIRLSLSLEER
>NC_015387.1|WP_013704237.1|1468076_1468445_-|response-regulator
MGKRVLLVDDEPFVGHLVRNLLVRDGYEVLVARNGREALDCLERGTEVHLIITDLAMPELDGFGLLEALRGKSVPPVLVLTARGHVEDERRALDLGAAGLITKPFSREGLLAAVRMHLEGSS
>NC_015387.1|WP_013704238.1|1468511_1469264_-|metallophosphoesterase
MRCGVDRFQLTRHTRTLAGLTAPVRVVHLSDLHYGPWIRKELVTRWVEAALREAPDLVVITGDFVDAGLRDGIEGLIQALDPLRAPLGVWGVWGNHDRSRFNPLDPLREALALAGVRMLENHGVQLRPDLFLAGVDDLWRGRPDPEAALAGWRGGARLLLSHNPDLLAELRTPVELVLSGHTHGGQVCLPGIGAIHTGSRYGRRFVAGWVEAPQRAFISRGLGVSALPLRWNCPPEIAVHELAPCHRSPK
>NC_015387.1|WP_013704239.1|1469286_1472304_-|preprotein-translocase-subunit-SecA
MLGLLKRIFDNNEREIQRYWKTVVEPTNALEAEVERIDDLAKAYAELREQHQKGASLDELLPRVFALTRESAKRYLGMRHYDVQLIGGAVLHEGKIAEMKTGEGKTLVATLPVALNALTGKGVHLVTVNDYLARRDAEWMRPVYRGLGLTVGVIQHSSTPDERRQAYLCDVTYVTNSELGFDYLRDNMALSPEQLVLRHDTPLHYAIVDEVDSILVDEARTPLIISGPAEKATDLYYRMAELAQKLERGEKPEPGEKDKEPTGDYTIDEKQRSVHLTERGIAKAEKLLGIEGLFSPENMEIAHMLIQAIRAKELYFRDRDYIVQDGQVIIVDEFTGRLMPGRRYGEGLHQAIEAKEGVKIERENQTLATITYQNFFRQYEKVAGMTGTAKTEEKEFQEIYGMDVIVVPTNRPVIRQDHPDVVYRSERGKFFAVVEEIAERYERGQPVLVGTISIEKSERLSAMLTEPRHYLPRLEMRVQSFLKAAAKQQGEAWERLKRLLERPANLREEALREFEPLLENAKGALKDAWEELKRSVHTLEVIRKGIPHQVLNAKHHEKEAEIVAQAGRSGTVTIATNMAGRGTDIKLGGNPEHMAAVLLEKQGFDRYEWKVELFIKKLVQGEEGEARALAAELGVSEETIEEIKRLRDACREDEKRVKELGGLAIIGTERHESRRIDNQLRGRAGRQGDPGESRFYVSFDDDLMRLFASDRVVAMLDRMGFDDSEPIEHRMVTNAIERAQKRVEDRNFAIRKQLLRFDDVMSRQREVIYAQRRTILLGKDEEVKEAALAMVEETVAGVAENYINPEIHPDDWDLASLKATLLDYIPAFETFEFEALRQEKAADAVEKIVQAGLEFYTKREEELGPPLMRAVERFVILNVVDGAWKEHLHNLDVLRQGIGLRAYGQRDPFQEYKFEATRLFNDMIAYIKGEVTKFLFRLKVEVEPPKPRAHAPVPPKAATPPARQATAAPQPAQARESGKKPKKIGRNDPCWCGSGKKYKHCHGRS
>NC_015387.1|WP_013704240.1|1472348_1473344_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MVVLGIETSCDDTGVGVVRDGRVLSNQVASQTQLHATYGGVVPELASREHTRVIDALVAAALEEAGVRLEEVDVIAATRGPGLIGALLVGLTYAKALAFALERPFVGVHHLEGHIYGALADRPDLAPPFLVLVASGGHTHLFDVPAEGRYELLGATRDDAAGEAFDKVARLLGLGYPGGPEIARLAEHGDPEAVPFTVPLKDQPGFDFSFSGLKTAAARFVEQGYRAEDIAASFQRVVVEALYTTVARAARARGRQKVVIAGGVAANQALRARFQESDLETVFPPKGMNTDNGAMIALAAWRRWQGRGDALTLAARPYLPLAEGSSPGREG
>NC_015387.1|WP_013704241.1|1473415_1474537_+|methyltransferase
MTLEAYHRLKRIPFAHGGLYAKPGARGYPDPVHDLLARTLEPIGERALDLNPGVGLTSLTLAHAGLAVDLIETSRAALRCLEATAREVRAWRVRRGLPWEVEPEAYDLVALPLPAERGSAWVRQCLIAASRALKPGGRLWLAGDRRKGFERYFKEARALVGYGVVVTRDGPYRVAVLEREGPAPAPEEAWRRFESTVLGQRLAFHHLPGVFSAGKIDPASLLLLEALEGPVRGLRVLDLGGGYGALGAPLARLGAEVTLVEDEWPAVLSAQRTLEANGLEGRVLHSDVDEALKEGEAYDIVVTNPPFHVGGNVILDVARAFVQAAYARTRPGGRFFLVANPFLKYEPLMEALFGNYRTARVDRYKVLVSEKPA
>NC_015387.1|WP_013704242.1|1474592_1476026_+|RNA-polymerase-sigma-factor-RpoD
MDKEKKRKKKAAQEVIDAPPSESTTKRRRRSAKKTEGTAEDVLESRAVRTLLQKGKKSGSLSQEEVRQVMEEALPNLDDDAFEESYEEVIDLLEGEGIDVLSEDEELEEPILEGEDDLSEDEPAIATRVSISDPVRQYLHEIGQVPLLTLEEEIDLARRVEEGEAAIEKLSEFTGLDAHLIKQVIRAQVRHGGRVPHIPGVDTEIDEETVQAVDARLRALPKPQKRYLHLARDGELARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRYKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLTRTARQLQQEKGREPSYEEIAEAMGPGWDAKRVEETFKIAQEPVSLETPIGDEKDSFYGDFIPDEHMASPVDAAAQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAYFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD
>NC_015387.1|WP_013704243.1|1476258_1477158_+|delta(1)-pyrroline-2-carboxylate-reductase-family-protein
MEHLSAETTAAHLPYPKLADAIAQVLQSWARGEAHAPERSVLSLPGGGTFLVMPATSPRIAITKLVTVHPQNATRNLPTIESEVIVIDAATGVRRGILEGKTVTARRTAALSLLAAKLLAPNPTGPLLIVGAGTQGRAHLEAFVEGLGVRQVYIASRTRQNAEALAAYAQTLGVHAEAVARPEEVLERAPLIVTATTSATPVLPPTVREDAFIAAVGAFRPEMAELPPTLIQRARVYVDTLEGAQAEAGDLIQAGVDWARVVPLQRALAQPRPTKGPVIFKSVGSALWDLAAAMLVYGT
>NC_015387.1|WP_013704244.1|1477145_1478609_-|DUF3084-domain-containing-protein
MNLWTLVGSLVLLAGLIAYVGDVVGRRVGRRHLRLFGLRPRTTALVFAILTGMIIALVAFFAFFFLAEDARRTILEAEQVRLERDRLREEVTRLSGEVQSYEGRVAQLFAERERLFQERDRLEANLNFAEFQLQEARRELEKLQAERDLLLEQVRSVREALAQREEELRKVEAERDAAEAEFLKLQAAQNQLLQELEELREAQSTVLSSADETRRRLEARLQAIREEIARLEEDRRRLRGDLNALLSEQYRLERSRRQLEEENARLAAQLEAAQLEERRLNASLARLKAEQARLEQGIEVLRQGLSRVLKDTVLAEVPLGEGRSSEQAWAEVVRKADVEARVAGFRGVLLPGEEQIDGWTGPGVLQARAQGITPEGKLVVGVRFVPTERRFVLGQVISMRELPPPRYQPERVREGLIALRKDAEERLLQAGILPERVAEGRLTLGDLARFQSSLADLTGNVVVGVVALEDLFTTGPVRVALQVLYVP
>NC_015387.1|WP_013704245.1|1478618_1479383_-|LPS-export-ABC-transporter-ATP-binding-protein
METALSHAIEEAQRARLMATGLRKRYGRREVVRGVDLTLGRGEIVALFGPNGAGKTTTFYMLVGFIRPNEGRIMLKGHDVTRMPMYRRARLGLGYLPQEPSAFRRMTVLENLLSILEHQPIPKQERMEIAMSLLEEFHIAHLKDKYAYTLSGGERRRLEIARALTTNPDFILLDEPFTGVDPKNVRDIQKLIEELRLRRGVGIFITDHSVRETLAITDRVYLMYDGQVVFHGSPEEFARDTGARNYYLGDEFEL
>NC_015387.1|WP_013704246.1|1479439_1479718_+|hypothetical-protein
MRVLGWILLILGIALALGIAGPILAVLALGLGLVGAVVGLALLPFLVLLGLVLGAIGLLVGLAAVVLKWGIPLLLVLVGLWLLLRDRAPQAA

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Crispr_ID: NC_015387_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_8

1919686-1919795

TypeIII

III-A

Consensus_repeat	Method
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACC	CRISPRCasFinder

1 spacers

csx1,cas10,cmr3gr5,cmr1gr7,cmr4gr7,cmr5gr11,cmr6gr7,c2c9_V-U4

The CRISPR arrays of NC_015387_8

>merge|NC_015387|8|1919686-1919795|CRISPRCasFinder
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACCGGATATACAACTTGCGCCCGGGGATTTTATCGGCGTGTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACC

>NC_015387|8|8|1919686-1919795|CRISPRCasFinder
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACC	GGATATACAACTTGCGCCCGGGGATTTTATCGGCGT
GTTGCAAAAAGGTCAGCCTCGTAAGGGGATTGCAACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_013704683.1\|1911104_1911449_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_015387.1\|WP_013704690.1\|1920031_1921333_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704682.1\|1910025_1911102_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|187792
NC_015387.1\|WP_013704681.1\|1909178_1909982_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|273987
NC_015387.1\|WP_013704685.1\|1912309_1913551_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl\|CDD\|224286
NC_015387.1\|WP_169311738.1\|1926004_1927669_-\|ester-cyclase	unknown	unknown	gnl\|CDD\|341411
NC_015387.1\|WP_013704686.1\|1913547_1914666_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NC_015387.1\|WP_013704689.1\|1917721_1919152_-\|TIGR02710-family-CRISPR-associated-protein	csx1	cd09747_csx1_CAS-III	gnl\|CDD\|187878
NC_015387.1\|WP_148230424.1\|1923355_1923724_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704687.1\|1914655_1916425_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cls000742_cas10_CAS-III	gnl\|CDD\|187810
NC_015387.1\|WP_013704691.1\|1922012_1923278_-\|transposase	c2c9_V-U4	-	gnl\|CDD\|223747
NC_015387.1\|WP_041658453.1\|1928669_1929668_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_015387.1\|WP_013704688.1\|1916491_1917709_-\|CRISPR-associated-protein-DxTHG-motif-protein	csx1	cd09732_csx1_CAS-III	gnl\|CDD\|187863
NC_015387.1\|WP_013704695.1\|1924521_1924791_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_041658036.1\|1925417_1925948_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704684.1\|1911451_1912306_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_015387.1\|WP_013704693.1\|1923720_1924365_-\|peptidase-C39	unknown	unknown	gnl\|CDD\|239103
NC_015387.1\|WP_174490741.1\|1927836_1928592_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224053
NC_015387.1\|WP_148230423.1\|1908973_1909210_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_169311737.1\|1924803_1924965_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|252976

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_013704683.1\|1911104_1911449_-\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	1.71332e-31
NC_015387.1\|WP_013704682.1\|1910025_1911102_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|187792	cd09661, Cmr6_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	3.37107e-53
NC_015387.1\|WP_013704681.1\|1909178_1909982_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|273987	TIGR02127, Orotidine_5'-phosphate_decarboxylase, orotidine 5'-phosphate decarboxylase, subfamily 2. This model represents orotidine 5'-monophosphate decarboxylase, the PyrF protein of pyrimidine nucleotide biosynthesis. See TIGR01740 for a related but distinct subfamily of the same enzyme. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis].	4.15647e-69
NC_015387.1\|WP_013704685.1\|1912309_1913551_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|224286	COG1367, COG1367, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	3.79054e-31
NC_015387.1\|WP_013704686.1\|1913547_1914666_-\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	3.38096e-89
NC_015387.1\|WP_013704689.1\|1917721_1919152_-\|TIGR02710-family-CRISPR-associated-protein	gnl\|CDD\|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	9.57203e-80
NC_015387.1\|WP_169311737.1\|1924803_1924965_-\|hypothetical-protein	gnl\|CDD\|252976	pfam05055, DUF677, Protein of unknown function (DUF677). This family consists of AT14A like proteins from Arabidopsis thaliana. At14a has a small domain that has sequence similarities to integrins from fungi, insects and humans. Transcripts of At14a are found in all Arabidopsis tissues and localizes partly to the plasma membrane.	0.0023838
NC_015387.1\|WP_013704691.1\|1922012_1923278_-\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.30222e-21
NC_015387.1\|WP_013704687.1\|1914655_1916425_-\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.14991e-92
NC_015387.1\|WP_041658453.1\|1928669_1929668_-\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.75351e-65
NC_015387.1\|WP_013704688.1\|1916491_1917709_-\|CRISPR-associated-protein-DxTHG-motif-protein	gnl\|CDD\|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	5.86335e-17
NC_015387.1\|WP_174490741.1\|1927836_1928592_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	2.68346e-101
NC_015387.1\|WP_013704684.1\|1911451_1912306_-\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	1.28579e-96
NC_015387.1\|WP_013704693.1\|1923720_1924365_-\|peptidase-C39	gnl\|CDD\|239103	cd02423, Peptidase_C39G, A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic). The cleavage is mediated by the transporter as part of the secretion process. Bacteriocins are antibiotic proteins secreted by some species of bacteria that inhibit the growth of other bacterial species. The bacteriocin is synthesized as a precursor with an N-terminal leader peptide, and processing involves removal of the leader peptide by cleavage at a Gly-Gly bond, followed by translocation of the mature bacteriocin across the cytoplasmic membrane. Most endopeptidases of family C39 are N-terminal domains in larger proteins (ABC transporters) that serve both functions. The proposed protease active site is conserved in this sub-family of proteins with a single peptidase domain, which are lacking the nucleotide-binding transporter signature.	7.75677e-29
NC_015387.1\|WP_169311738.1\|1926004_1927669_-\|ester-cyclase	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	2.74976e-48

>NC_015387.1|WP_013704689.1|1917721_1919152_-|TIGR02710-family-CRISPR-associated-protein
MPEKALNDPQALKEALEAAWAEYKARVEEGGDPQTLYRERVWPLLLALWRAEPPVHPGRQTFALSIHTLGTSPEAAIQAILGTGAEEVYVFHTEETRRFLPRLREETGKEVYPLEIQKSDVAAIYRKVRELLEKRPEALVALDVTGGTKAMSAGLAAAGFFFQRFFPGVRVVYVDSGEYDVKLRRPRAGTERLIVLPNPHEVVGEVDALFAKELYAKEDYGGAARYFSGLVGKTGDQAYTLYAMLAEMYAAWQALDFKEAARKGQTLQRALEKDTWLQHPLGQHLSRLRRQVELLEAAAEFLSTKDLGKQRGVLGVAATLLHLSERTAKKQPVLAALYAYRALELLLQERLYRFDRRRAETPNLSPEEEAALRDELAALLPDTDEIRVGPKLGLLEVLAFLRVLGDPVLKKKGVKELQGLAGVLKARNQALLIHGLEVPSEKQVKQVQTALRVLLGALQEELAYRTDLKTIPLERV
>NC_015387.1|WP_013704688.1|1916491_1917709_-|CRISPR-associated-protein-DxTHG-motif-protein
MGRERPRKLLITLIGQARTAEGGGRYKMVPYRFPDGTRHASAFFGVSLFEYFHRRGETPDLLIVGTSGSTWQALEDFFLLEDVGFTAEAQAFLDRWHEEAKVVEERERLLADFLGVDVTLLPVEDPPSGEVLTERVFEDLSARGSYDEIILDITHAYRFMGYVLFAILLSLRHVWRCQVRIFYGGVELPKIEGDSQVIELKALEDLVRLDEALSILQTTGNFVPYFALASEEEKAQRAYLALEVNRQENVASWLKELAEVEGPPLAKGVVSKEVKQILKELEGECFEDKLINRARFFFERDQVFKAVLLLYEGLVVAGVKRFGLGDPLNYEMRRDAQDKLEKLLRDHPNSAWVQIYKKVRLLRNAVAHGTRPRDGKVQQVLGDWRLLKDTFQEGLRLYQEIKKDQ
>NC_015387.1|WP_013704687.1|1914655_1916425_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MDWLLVLSLGPVQEFIATARRTRDLFAGSRLLSEAAQRAAEVLADAVGVERLIFPAPEGKGDLEKLGAAGIPNVLLLRVPEGQDPRVLGEKALAAAREYLRGKALEVFRAREAHLEMEAALAQVEDLLEGYYAYAPLQEGYPKTRARVMALLAARKNTRDFAPVTWGKAEFKSSLDGAREHVLRLPKDREQAEATRLSLGLRRGEYLSGPDLLKRWWRTEGSFLSTSHAAVLPFWEGVRQAGAQGLLEEAFKDLAAWVGEAARADTWHPVLRNTPFAHWNVHLLYESRLEEFLALKDEGVKARVQERLKRLWRDLGLKGVKAPPGAYYALLHADGDRMGETIDRQQDPKAHRELSRRQALEFADKVKRIVEAHQGGLVYSGGDDVLALLPLHTALRAAWALARRFRDVVKPYGKPEAPPSLSVGLAVVHHLEPLQDALDLVRRAEKLAKEGRTGEEKRNALVVAYSPRSGTELMVRGRWDEDPRLTQRLCRYADLLRMGAIPSRAAYELRGLCLEAEGVLSEEALVAEALRILGRKEMKGAYREELSRWVRTGKDVKRLADELILARPFAEALEQARVPLENREVYGAH
>NC_015387.1|WP_013704686.1|1913547_1914666_-|type-III-B-CRISPR-module-associated-protein-Cmr3
MLIEPRDPLIVRDGRPFTNSPGARARSLPFPLPQTLAGAYRARRGFSEGLRFPEDAHRVLSWGVRGPLLAEWGGAAWRLLVPRPLDMLKLGKAVYALRPLDPPEGCGTNLPEGLCPVGLPRPDLKTKPEVLPRFLYWDCVLDWLVRDAPEGFHPEGHDGPTPEVRTHVSLDPGTQTAREGFLFQTSGLEFARQQKEDSASLHGIRRMALTLWPEDGVEVEGVHPLGGERRLALWQRGGPEVPGVPEGLLEGLLARRAARVVLLTPAFFRGAFLPEGRTFFGAEVVAVVSGRPVAVSGWDLKEGKPKKSRRAVPAGSVYFVRLPEAWGEAAVRDWLLKVWFQNLSDEEQDRKDGYGLGAVGLWSGQLMRWEEA
>NC_015387.1|WP_013704685.1|1912309_1913551_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MRKEYTDAFAPRRREVEGGLVRHDGVRILTWERTYRLLTPLFGGGVEPRHADPLTAVRASEVRGQLRFWWRAVRGWQAQGSLKRLLALESRLFGSAGEGGASPLLVEVEPLEKGKEAHPFEDQPGRGFPRARRDVAHPYLAFPLQRTKQDSKNYPVRRGVRFRLRLRFPERVGDLDVKEELEAALWAWETFGGIGARTRRGFGALMREGSRPLGEAEIREKLRAYAREAGWPEGVPHLTPASLVRVVPLSWREVAEAYQAFRQSRREGQGRNRPGRSHWPEPDEVRRRTEQYAFHHKPQHPVRKFPRAQFGLPIIFHFKDREVHPDATLKPQAADRLASPLIFRPLAEKACVVAVLEAPRTPPGGVVLEWKGRECGVETRLSPEEAEKIEPLRARGGEPDPLRAFVMHLEARR
>NC_015387.1|WP_013704684.1|1911451_1912306_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MHQTETALLFIHALSPLHAGTGQGVGAIDLPIAREKATGIPYLPGSSLKGVLRERARQWDEAMLFAVFGPDTENAHEHAGALQVGDAKLLLLPVRSLYGVFAYVTSPYLLERFRREAALVGLTPPQTPTVPGRTWALAASGAQVVEGSNAYLEDLDLEVKEAPHVAEWEAWLAERTEAPVKGRLLLVHDDLMGFLLETVTEVVARIRLDDETKTVARGALWYEESLPAESVLYSLVRAERSFRKGQEMLPEAVMALFKGLLKGALQLGGKATVGRGLCRVQVGR
>NC_015387.1|WP_013704683.1|1911104_1911449_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MHTRAQRWAQDAYERVQARARTGEAGEYKDMALKLPVLIRQAGLAQALAFVESRGKAAHKSLGEDLARTLGYEGLRDLSAQARKAPLLEYLRLTREVLGAADWYKRFAQALIEE
>NC_015387.1|WP_013704682.1|1910025_1911102_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MARKEPNADSSRRDALRGIRFPSHREPHRGLWLDKYIRTVREEDTDAKRDLVREVAGCGEPKEYRAFFTRYRKALEELGAEVREARTLGRLVVGLGGEGVLETSLTLHRTYGVPYIPGSALKGLASRYAHLYLEGEAWRRNLKEFKRGAAQKALFGDLEEQGALVFFDALPLPGTYALHPDVMTPHHAEYYGGGGAPPADWDSPVPVPFLSVTGTFLLALAPVPGLSPEVARPWLEAAWRILAWALKEEGVGAKTAAGYGRMELEGGGAARAPSREGAGARFSPEYEDLKIRLRGTSYRELRAFLEAHAALIQALSPEEAQDLRQAMHAKGFLNNPRDLKRWAKGREALKQALERLGL
>NC_015387.1|WP_013704681.1|1909178_1909982_-|orotidine-5'-phosphate-decarboxylase
MWDFVEEVTRRPPLVLGVDPRPAWHPGKDKLGQIRRYSLEVMEALAPRIAAVKFQAAFFEALGPEGYALMHELAAAARVMALPVIWDVKRGDIGSTAQAYAQAYLEAYPGSAVTVNPYLGEDAVAPFLEAAARSRGMVFVLVKTSNPGSGMFQDLEVAGRPLYRVVAEAVAAWSERYAVGRWSRVGAVVGGTYPERVRELREGMPRSLFLVPGLGAQGGAVLRGEGLLLSASRALYYPGGRPDVGVALRQARAYLEALRAPMAEGSS
>NC_015387.1|WP_148230423.1|1908973_1909210_+|hypothetical-protein
MGARAEPTLPRPLQALAAGFYPQREDWGSHTLPADFLIGPDGRIQIAHYGRDIADHLPLPRLYQALGTPSSNPPPSVP
>NC_015387.1|WP_013704690.1|1920031_1921333_+|hypothetical-protein
MLKRVLRQTIGENTQRSRCLPILAALSLTLLAACAPQTTLPPIPDVTQIPMPLPTGIPQGKPVVQALPGTPMPLADEFSSYPTGAVLPAVAPDRYGLLRFNQGWEKISIVEAFTSEGKLDKAVRLEGGLGEGFLTAGAPDWTDYRVTLRVKTHEACCTESAIRARLFMNETGSKALEFRIGFYGVRLIKIAGDQSFTLIDRPELETLGRAVLRDQNWHDLSFELHSDGTVTVRVDDTEVVTWKDADYRQGGFGIGPINTTFFLDDLRIEPLASQPQPPEATAPQPGDFCGYRAGAELPHQRFEATGPVSLTLLGGYSAARDYRVGYYETARPEVSVALLEYAGAFDPAVCLTPPPTATFTPSGPFGLAHTYEHYGEKTIYTEDARNGGEPRFRAYEALNPEGRAVGVLLLLEDWVDNDYDDVGLLLEGARPVG
>NC_015387.1|WP_013704691.1|1922012_1923278_-|transposase
MGAKNEKIKASLAETRARRENQRPRTFVLKLQNLSKNKERTLERAFLEAKWLTNWIIADIERLQLPLNKVHEVEAKAGDALEPCKLRVLGAQVKQRIGRRIQEDLRGLHALKQNGHKVGRLGFKRRVDAIPFSNQAFTLRSRGKENRVHLQKLGEFRALGLHQIPQKAEVANAVLVRKPSGHYLHVTVYVPKDEPKPLPDPGNPNQATDFKAVGVDLGLKNQAALSNGFVLRWRVRETDRLKKLQRKLSRKKKGSKNREHVVHRIRREHEKLRWIKQDIRNRVLALLRQYDLVAVQPDRIKGWQALWGGKVQGAALGGLLEALRTRLPTLVATERNAPTTRTCSSCGHLNPKVPLDRRVFTCEACGFRIDRDLNAALNVLTMAWPAARALGLDRPEVTPLEWEAAGRILGPNPRIRLSHAT
>NC_015387.1|WP_148230424.1|1923355_1923724_-|hypothetical-protein
MTLRKEKTAVLRRLLLILLGLWGVGWAQPALEPVDPLVRAVPTPGRFTLNAALGYAPDARVAFGVDEAQGPYTDRFTTYGLHTSVGLGYAVTETVSLGAGFTYALAYTQTLRTYQTGGSGGL
>NC_015387.1|WP_013704693.1|1923720_1924365_-|peptidase-C39
MRLHALLCLALLAAGLGLAAPTPYCALRYTHVVGQTDWYTCGAAAVATLLTYYYADPATEREVLEIAFKETQAAGKDPLKGLTALALKRALEQRGYAVKAYRVNLEQLVAYFEAGGLPLIAHVTQPQRHFLVIAGLLRDPRTRRPHLLLADPSWGRRVLEVEDLLHDKGFSGVVLLAIPKNSAQLEQVQALQVQELAWAQQSLNRLRALRGWMP
>NC_015387.1|WP_013704695.1|1924521_1924791_-|hypothetical-protein
MKKAVPLMIAALLANAFLPVMARSNPLPPVPEVPLPAGQELSDAELLEASGAFLPLVGAFLAGAALGVGLGYVAVKVGEPALETLMGGE
>NC_015387.1|WP_169311737.1|1924803_1924965_-|hypothetical-protein
MLPEGTPLLDAELEATQGELGSLVAACTAGPAAMAFCAGLGVGLLVGAWLASR
>NC_015387.1|WP_041658036.1|1925417_1925948_+|hypothetical-protein
MTVHLTPPLFTEESLPKFRAFVAQAEAAGASKTVLGQLRGALRSAEIEWETLQQLDPATIQELRRQIAPAAQPGPAAPQGLFNCTRATAGPTTARPGAKAYAKGSCVNATNHVYARAEAAGEVRAARDAGWNGAFASAFQYGNWACASYGAASAYLSIGGFRITVDSSTAAYDRCR
>NC_015387.1|WP_169311738.1|1926004_1927669_-|ester-cyclase
MRSIARKEVVRVRPEAPIAEACRLMEENNIGCVVVSDNGKPLGLVTDRDLTLRVLRQGMDPKKTKVEQVMTREVLTLNEDMGLLEALEAVRGKPIRRFLVVNDKGELSGIFTLDDVMYLIGREMADVASIMELEAPPERPASLEGRNQAAARRIIEEGLNKGNLAALDEVIAEQLVDHDLPPGLPQGREGVKQLFTQMRRAFPDLRATIEDAIAAGDRVVLHQTLQGTHKGELFGRPPTGKRIAFREMHVIRFENGKAVEHWGITDLPERLGTAGDPAQAERNQAVVRRYFEEVWNQGRFDGLREIVTADYVNHDPAVPDAGRGPESVRALVEYYQKAFPDTRFTIEEMHAVGDRVVTRWKAQGTHKGELMGIPPTGKKVVVTGLTIDRLEGGRVKEGWTHWDTLGMLQQLGVLSSPEAAGRNKAALRRLYEALDRREFRVMDEILAKNCVAHIPGFPDPMDCATFKQFIRGLYNAFGNYEHVIEDLFAADDRVVARLILRGTHEGEFKGIAPTHKSFAINSTVIARFADGRLVEYWGSPDLLGLMQQLGVIEG
>NC_015387.1|WP_174490741.1|1927836_1928592_-|ATP-binding-cassette-domain-containing-protein
MTVYPGEVHCLLGDNGAGKSTLIKIFAGVYPPDRGEMLVEGKPVRFRSPREALDHGIATVYQDLAMIPLMSITRNFFLGREPTRGWGPFRRFDLAFAERVTREEMHKIGIDVRDPNQAVGTLSGGERQSVAIARAVYFGAKVLILDEPTSALGVKEAGVVLRYIAQARARGVGVVFITHNVHHAFPVGDRFTLLNRGRSYGTFKKGEVTREEILTMMAGGEELEALSAELEEFARTDADQESQGLDDATRS
>NC_015387.1|WP_041658453.1|1928669_1929668_-|ABC-transporter-permease
MRKPSLLRRLLGRPELGSAAGVVLVFSIFAVIAGDRGFLSWLGTVNYLEVSAQLGILAVAVSLLMIAGEFDLSIGSMIGVAGMAIAIPVKLFGWPVWAGVLLAFALALAVGYFNGWLVIRTGLPSFIVTLAALFILRGLTIGVTRLLTHRTIVSGLHPAIQEDPIAPIFTAAPFGVPAAVFWWLGLTAIGAWVLFRTAFGNWIFGAGGDAQAARNVGVPVARVKITLFMGTSFSAALLATLQVLDAGSADVLRGQLKEFEAIIASVIGGNLLTGGYGSVIGASLGALIFGMVRQGFFFTGIDTDWFQVFLGAVLLVAVMFNNYVRKRAVEAR

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Crispr_ID: NC_015387_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_9

1990739-1991228

Orphan

Consensus_repeat	Method
AACCGGGTGCAGGACCTCACCCCCCTC	CRISPRCasFinder
GGACCTCACCCCCCTCC	PILER-CR
AACCGGGTGCAGGACCTCACCCCCCTC	CRISPRCasFinder

5 spacers

The CRISPR arrays of NC_015387_9

>merge|NC_015387|9|1990739-1991228|CRISPRCasFinder,PILER-CR,CRISPRCasFinder
AACCGGGTGCAGGACCTCACCCCCCTCGCCGCGCTCGAGGACCTCGAGTACCTCGAGCTGAGCTTCAACCGGGTGCAGGACCTCACTCCCCTCCAGCACCTCACGCGGCTGCGCGTCTTGTTCCTTAGGGGGAACCGGATCCAGGACCTCACCCCCCTCCAAGGCCTCACCCGGCTTCAGGAGCTCGACCTTAGGCGCAACCGGGTGGCGGACCTCACGCCCCTGGCGCGCCTCACGGAGCTGCGGTTTTTGGTGCTGAGCTTCAACCAGGTCCGGGACCTCACCCCCCTCCAGGGCCTCGCGCGGCTTCAGGGCCTCGTCGCGAATCACAACCAAATCCAAACCCTCGCTCCCCTCCAGCACCTTCGCGCGCTCAAGACCCTCCTCCTGAGCGGAAACCAGATCCAGGACCTCACCCCCCTCCGGCCTCTCTCCGCCCTGGAGGTGCTCGACCTGAGCGCGAACCACGTGACGGACCTCACCCCCCTCG

>NC_015387|9|9|1990739-1991030|CRISPRCasFinder
AACCGGGTGCAGGACCTCACCCCCCTC	GCCGCGCTCGAGGACCTCGAGTACCTCGAGCTGAGCTTC
AACCGGGTGCAGGACCTCACTCCCCTC	CAGCACCTCACGCGGCTGCGCGTCTTGTTCCTTAGGGGG
AACCGGATCCAGGACCTCACCCCCCTC	CAAGGCCTCACCCGGCTTCAGGAGCTCGACCTTAGGCGC
AACCGGGTGGCGGACCTCACGCCCCTG	GCGCGCCTCACGGAGCTGCGGTTTTTGGTGCTGAGCTTC
AACCAGGTCCGGGACCTCACCCCCCTCCAGGGCCTCGCGCGGCTTCAGGGCCTCGTCGCGAATCACAACCAAATCCAAACCCTCGCTCCCCTCCAGCACCTTCGCGCGCTCAAGACCCTCCTCCTGAGCGGAAACCAGATCCAGGACCTCACCCCCCTC	CGGCCTCTCTCCGCCCTGGAGGTGCTCGACCTGAGCGCG


>NC_015387|9|5|1991014-1991228|PILER-CR
GGACCTCACCCCCCTCC	AGGGCCTCGCGCGGCTTCAGGGCCTCGTCGCGAATCACAACCAAATCCA
AACCCTCGCTCCCCTCC	AGCACCTTCGCGCGCTCAAGACCCTCCTCCTGAGCGGAAACCAGATCCA
GGACCTCACCCCCCTCC	GGCCTCTCTCCGCCCTGGAGGTGCTCGACCTGAGCGCGAACCACGTGAC
GGACCTCACCCCCCTCG

>NC_015387|9|10|1991135-1991227|CRISPRCasFinder
	GCCGCGCTCGAGGACCTCGAGTACCTCGAGCTGAGCTTC
AACCGGGTGCAGGACCTCACTCCCCTC	CAGCACCTCACGCGGCTGCGCGTCTTGTTCCTTAGGGGG
AACCGGATCCAGGACCTCACCCCCCTC	CAAGGCCTCACCCGGCTTCAGGAGCTCGACCTTAGGCGC
AACCGGGTGGCGGACCTCACGCCCCTG	GCGCGCCTCACGGAGCTGCGGTTTTTGGTGCTGAGCTTC
AACCAGGTCCGGGACCTCACCCCCCTCCAGGGCCTCGCGCGGCTTCAGGGCCTCGTCGCGAATCACAACCAAATCCAAACCCTCGCTCCCCTCCAGCACCTTCGCGCGCTCAAGACCCTCCTCCTGAGCGGAAACCAGATCCAGGACCTCACCCCCCTC	CGGCCTCTCTCCGCCCTGGAGGTGCTCGACCTGAGCGCG
AACCACGTGACGGACCTCACCCCCCTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_041658059.1\|1988054_1989011_+\|aldo/keto-reductase-family-protein	unknown	unknown	gnl\|CDD\|381300
NC_015387.1\|WP_013704759.1\|1998553_1998871_-\|(2Fe-2S)-ferredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239278
NC_015387.1\|WP_013704746.1\|1983837_1984833_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|276809
NC_015387.1\|WP_013704760.1\|1998867_1999251_-\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|224523
NC_015387.1\|WP_013704753.1\|1991382_1992195_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NC_015387.1\|WP_013704754.1\|1992204_1992411_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704748.1\|1985284_1985815_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NC_015387.1\|WP_148230426.1\|1995759_1996194_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704745.1\|1982719_1983046_+\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|223424
NC_015387.1\|WP_013704755.1\|1992546_1995174_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NC_015387.1\|WP_013704747.1\|1984829_1985288_-\|cytochrome-c-type-biogenesis-protein-CcmH	unknown	unknown	gnl\|CDD\|377161
NC_015387.1\|WP_013704762.1\|2002033_2002738_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176499
NC_015387.1\|WP_013704757.1\|1997538_1997757_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_015387.1\|WP_013704749.1\|1985811_1987776_-\|heme-lyase-CcmF/NrfE-family-subunit	unknown	unknown	gnl\|CDD\|224061
NC_015387.1\|WP_013704761.1\|1999423_2001991_+\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NC_015387.1\|WP_013704758.1\|1997804_1998554_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379861
NC_015387.1\|WP_013704751.1\|1989069_1990419_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NC_015387.1\|WP_041658055.1\|1983096_1983282_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704744.1\|1979699_1982723_+\|DUF2309-domain-containing-protein	unknown	unknown	gnl\|CDD\|378378
NC_015387.1\|WP_148230425.1\|1983344_1983638_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_041658059.1\|1988054_1989011_+\|aldo/keto-reductase-family-protein	gnl\|CDD\|381300	cd19074, Aldo_ket_red_shaker-like, Shaker potassium channel beta subunit family and similar proteins. This family includes voltage-gated potassium channel subunits, beta-1 (KCAB1B), beta-2 (KCAB2B) and beta-3 (KCAB3B). KCAB1B and KCAB2B are cytoplasmic potassium channel subunits that modulate the characteristics of the channel-forming alpha-subunits. KCAB3B is an accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. The family also includes Drosophila melanogaster Hk protein, a founding member of aldo-keto reductase family 6 member B1 (AKR6B1), as well as voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa, founding members of AKR6C1and AKR6C2, respectively. Hk protein, also called hyperkinetic, is a beta subunit of Shaker (Sh) K+ channels and shows high sequence homology to aldoketoreductase. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	1.32002e-165
NC_015387.1\|WP_013704759.1\|1998553_1998871_-\|(2Fe-2S)-ferredoxin-domain-containing-protein	gnl\|CDD\|239278	cd02980, TRX_Fd_family, Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.	1.04175e-16
NC_015387.1\|WP_013704746.1\|1983837_1984833_-\|c-type-cytochrome	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.02439e-14
NC_015387.1\|WP_013704760.1\|1998867_1999251_-\|acyl-CoA-thioesterase	gnl\|CDD\|224523	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism].	8.07284e-44
NC_015387.1\|WP_013704753.1\|1991382_1992195_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	3.14584e-54
NC_015387.1\|WP_013704748.1\|1985284_1985815_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.22779e-43
NC_015387.1\|WP_013704757.1\|1997538_1997757_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.9212e-29
NC_015387.1\|WP_013704745.1\|1982719_1983046_+\|P-II-family-nitrogen-regulator	gnl\|CDD\|223424	COG0347, GlnK, Nitrogen regulatory protein PII [Amino acid transport and metabolism].	2.13045e-15
NC_015387.1\|WP_013704755.1\|1992546_1995174_+\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NC_015387.1\|WP_013704747.1\|1984829_1985288_-\|cytochrome-c-type-biogenesis-protein-CcmH	gnl\|CDD\|377161	pfam03918, CcmH, Cytochrome C biogenesis protein. Members of this family include NrfF, CcmH, CycL, Ccl2.	1.51264e-41
NC_015387.1\|WP_013704749.1\|1985811_1987776_-\|heme-lyase-CcmF/NrfE-family-subunit	gnl\|CDD\|224061	COG1138, CcmF, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones].	1.92654e-139
NC_015387.1\|WP_013704761.1\|1999423_2001991_+\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NC_015387.1\|WP_013704758.1\|1997804_1998554_-\|hypothetical-protein	gnl\|CDD\|379861	pfam16575, CLP1_P, mRNA cleavage and polyadenylation factor CLP1 P-loop. CLP1_P is the P-loop carrying domain of Clp1 mRNA cleavage and polyadenylation factor, Clp1, proteins in eukaryotes. Clp1 is essential for 3'-end processing of mRNAs. This region carries the P-loop suggesting it is the region that binds adenine or guanine nucleotide.	6.96085e-24
NC_015387.1\|WP_013704751.1\|1989069_1990419_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.33436e-114
NC_015387.1\|WP_013704762.1\|2002033_2002738_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176499	cd08556, GDPD, Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins. The typical glycerophosphodiester phosphodiesterase domain (GDPD) consists of a TIM barrel and a small insertion domain named the GDPD-insertion (GDPD-I) domain, which is specific for GDPD proteins. This family corresponds to both typical GDPD domain and GDPD-like domain which lacks the GDPD-I region. Members in this family mainly consist of a large family of prokaryotic and eukaryotic glycerophosphodiester phosphodiesterases (GP-GDEs, EC 3.1.4.46), and a number of uncharacterized homologs. Sphingomyelinases D (SMases D) (sphingomyelin phosphodiesterase D, EC 3.1.4.41) from spider venom, SMases D-like proteins, and phospholipase D (PLD) from several pathogenic bacteria are also included in this family. GDPD plays an essential role in glycerol metabolism and catalyzes the hydrolysis of glycerophosphodiesters to sn-glycerol-3-phosphate (G3P) and the corresponding alcohols are major sources of carbon and phosphate. Its catalytic mechanism is based on the metal ion-dependent acid-base reaction, which is similar to that of phosphoinositide-specific phospholipases C (PI-PLCs, EC 3.1.4.11). Both, GDPD related proteins and PI-PLCs, belong to the superfamily of PI-PLC-like phosphodiesterases.	1.03928e-60
NC_015387.1\|WP_013704744.1\|1979699_1982723_+\|DUF2309-domain-containing-protein	gnl\|CDD\|378378	pfam10070, DUF2309, Uncharacterized protein conserved in bacteria (DUF2309). Members of this family of hypothetical bacterial proteins have no known function.	4.66696e-164

>NC_015387.1|WP_013704751.1|1989069_1990419_+|FAD-binding-oxidoreductase
MLAGTLRQVLGEAKVSTSPSVLEAHGRDEGYPEVRPPLAVVFAETVADVQAVLEVARREGVPVIPFGAGTSLEGALVPQGPAISLDLSRMNQILEVRPEDFVAVVEPGVTRKRLNERLRREGLFFPVDPGADASLGGMAATNASGTTTVRYGGMRANVLALQVVLANGEVLELGRAVRKTSSGYDLKDLFIGSEGTLGVITRLTLKLHPLPEHVHTLRVFFPSVERTAEAAYAILASGLPVARLELVDDLALRAVNRYLDRNYPERPALFLEFHSATAAAMQEESRFALELVREAGALEVEAAMTAEERTAQWEARHQAYWALVNLFPQRKYLITDTAVPLSRMPELVGYARALMDEMRLEGNILGHVGDGNFHTLIAARDDAYARAEAFAERLVARALELGGTATGEHGVGLRKKKYMPLEHGNALAWMARLKTLFDPEGLLNPGKVV
>NC_015387.1|WP_041658059.1|1988054_1989011_+|aldo/keto-reductase-family-protein
MRYRKLGKWGLKVSEISLGAWVTYGNTVKDKDTIREIVKLAYDHGVNFFDNADVYAHGLAEEIMGEILQEFPRHTLVLSSKVFWPMSEDVNDRGLSRKHVRESIDKSLKRLRVDYLDLYFAHRYDPEVPMEEIVTTFSGLVDEGKILYWGTSEWPASRIAEAVTFARANGLHPPVVEQPQYSMLYRERVETRILPEAERFGMGLVVWSPLAMGMLTGKYDHGLPEGSRFAQYEQFREMFLTEENREKVKELKRVADELGLTRTQLALAWVLRQGQVSSAITGASRPEQLKESLGAAGVDLPEEALKEIDAILGNAPQE
>NC_015387.1|WP_013704749.1|1985811_1987776_-|heme-lyase-CcmF/NrfE-family-subunit
MTPGAVGNLALLVALLFTVAGLVLSGLGWYTRDVRYVRMARRAAGLVFLGALAAFLALEWALLTDDFSITYTARTHSVKSPTWVKIATLWAALEGSLLLWGMLQALYTFLAARRLKDYWMAPVALGTLFAIQGFFFGVLLFVENPFTPVPNPPTDGPGPNPLLQNHWMMAVHPVLMYLGFVGLSVPFAYAVAAMVSRRYQSWVRETKWWTLIAWGFLTAAIFAGGWWSYEVLGWGGYWAWDPVENASFIPWLLATAFVHTAMVQERRGLLRGWNFGLITLTFAGTVFGTFLTRSGVIQSVHAFASGPIGPIFLGFFLVVLAVGFMLLSRISSEVRDAGSVRLVSREGALFASAVVFATMAFVVVLGTLFPLLVEATRGLKVSVGAPFFNQIFIPLGAMMLLLMGIGPVLPWKRTQSEVLRNLAWILGVLVLGFLGGLAVGWTVGVSLAVGLFAYNVAAIVLMVAEGVRTRARSTGEAWAVALVRQATQARRRYGSHVVHFGVALAALAIAFSQAYRVDAQKTLRVGETWEVLDTRITLLGVRAQDEGNRFAVLAPLELEGIGRLEPRLHYYPTRRGPLAAPDVGYTLGRDYYLTLQAFDEENGAWATLRLVVTPMVLWLWVAGALILLGTMYILWPSGQRFTASIPTATGGGRV
>NC_015387.1|WP_013704748.1|1985284_1985815_-|TlpA-family-protein-disulfide-reductase
MKRWLIWGTVLVLGGIFWWGLGRDPGELKSVLIGKPAPDFELPLFPRYQEEYGETITLERFKGQPVVVNFWASWCYPACWNEAPRLEAAWRKYRPQGVQFIGINIQDKRADAEAFLDRFGLTFPHGIDPPGRVAVDYGTYGVPETFFIDKDGIVRYRFAGEISSEELEKRIQEILP
>NC_015387.1|WP_013704747.1|1984829_1985288_-|cytochrome-c-type-biogenesis-protein-CcmH
MRRLRLWMALLLVWGGAWAVEDGPPPDLSPEVFQIAKELRCPVCQGESIAESNAELSQESRRLIAEMLAEGKSKEEILQFFVDRYGEWILYSPPRKGITLWVWIGPVLGLGAIGYGIFRYLAEVRRREEALAQAVDEAMLRRVEREIEEGEP
>NC_015387.1|WP_013704746.1|1983837_1984833_-|c-type-cytochrome
MTVGAWILLAILVLAGGVYMLAPVRGRSEPFPEDPRPEELREELNLLKNEARELVGAERRRLLARIAHLERTLQEFAPAPSTTRRPAAWVYGLAVLGVVVVGAVLWRYTLPRLPGETVTTAIRVEDALRLQELRQEAESANTAQSWLRYADFAWEVGDFTRAAEGYAAVLRLNPREPRALERMGKLLFISGRFDLAANVLVLATQLDPNEPEGWLFLGSAYYQLAQMKEAVQAWERYLALDAGDANQVAPLIEKARSLADAPLGQRVYAVSCAACHGADGQGGTGPRLKGNPVVEVSDAVRGIITQGMGAMPAIPLDEERLEALLEYLKNL
>NC_015387.1|WP_148230425.1|1983344_1983638_-|hypothetical-protein
MDIAVETRRVKCTVHPDSIHTALIHTVRRLLTPNGVQQGAQASMIYSEPLQSPPETQEAPTCTDNKIVTVVFLQVAVLRAEACVVARCVRGPAAWSW
>NC_015387.1|WP_041658055.1|1983096_1983282_-|hypothetical-protein
MHERARKSLEGLVEAVRQRTELAQAVRGETVEAGPELANFAGVTDVHAQHKRQPEDATEEA
>NC_015387.1|WP_013704745.1|1982719_1983046_+|P-II-family-nitrogen-regulator
MKGLTLYPMKKVEIIVRGEDLSFVLDLLERANVSGYTIVHNLSGKGSHGFHEGHLLFNEEDTLAMVVSVMPEEKARSILEGFAPFLNKHSGVVFVSDTMVSRIEKFKR
>NC_015387.1|WP_013704744.1|1979699_1982723_+|DUF2309-domain-containing-protein
MQLGRKLWIRSLVHVAAEAVPFFWPMRIFVHHNPLHELEELPFEEAVKVGERLFGGKGYLRRAQALKLLRNGPLKERHLKTKVRALAQRIHPRPAGIDVEALLYTLLTSERRPWQNRVRPDLPPEAVRTLAQALQEDPKAACDAFLRSIGEDLTLYEAIDQVTGAALGELIDDLVVKGVMDFLDEGQAAISMPHREQGLFQAWKALARHNLRFRLKIGPHFRALVQRFSSPEEAIEYVLTTLKIPEALWENYIRRELTRLKGIVGFIRWRQANRDYYWQRRFPADIVDYTAIRLLISLAVLQSRTRRLPFRTDYAAFTAFVRHAPEQTYLRREYFTGRAALPYAETLPPHFNRPHPFVQTYTQQKAAWEAKVFLTFLADWLEAAHLSLNALSPETILDLHALYTRVTEEEGKVWLEALEDSLLEDLLSQIRLEARPEPASPKAQVLFCIDVRSERYRRNLERLGRYETFGVAGFFGVPMAFVELHKGHEEFLCPALIRPRNVVLDMPQRREPRRENLFKRVLHDLKENILTPFITVEALGFLFGLDFVGKTFLPVGYTRAREAFLDARVHTKPLLDRLAPEEIEEVTRTLYGEVVRTALEKELGLRNVSSAQLHALFEDAVANRERSDVLSALGVPEAAHPALLRTLRETYRVERGYVELVKEKLRGIGFSREEQAALVANTLRSIGLTQGFAPLVLVLGHGSRSENNPYESALDCGACGGAAGTHNARVFCFMANHPKVRELLKQKHGISIPETTHFVPGLHNTTTDAVQLYDLEYLPSKLLPVLEGVRADLEAATLHTAQERALELGVKPEYAEVLEHAYDWSQVRPEWGLSGNYAFVIGRREVTRALDLKGKVFLHSYDYRVDPKGRLLENILSGPLIVGHWINMEHYFSTTDNEAYGSGSKVYHNVAGRIGVMTGNVSDLRTGLPAQTVLKQGEPFHLPVRLIVLLEAPFAFARTAIERVHKVRELMHKGWLNMVVLDPEERVVRRFMQGAWRVFGSVEEVQR
>NC_015387.1|WP_013704753.1|1991382_1992195_+|SDR-family-NAD(P)-dependent-oxidoreductase
MRLSGRLVLVTGASSGIGWATTRRLAHAGARLALVARRREALEALAREIQSGGGMARAYPADLGDPTAVRRMAEAVRRELGVPDALVHAAGAGRWLFVEETPPEEAVRMMQAPYFAAFFVTQAFLPGMLERGRGVVCVINSPAALQPWPGATGYVAARWALRGFTEALRLDLRGTGIAVCSVVAGRVRSAYWQHNPGAIERVPRLARLIPDLTPEAVARVVVRALEKESRLVVVPWALRVMYALHPFAPRLAEALVWRTGYRHPRAGRRG
>NC_015387.1|WP_013704754.1|1992204_1992411_+|hypothetical-protein
MNRTPFKVYRLSGFWAYLLLALAGLVGLFLTVWLLATALAVSALLLVAGGLVYAWRRFVMRRRMLPPR
>NC_015387.1|WP_013704755.1|1992546_1995174_+|leucine--tRNA-ligase
MEKYNPHAIEPKWQAYWQEKGLMKAKEEGEKQYVLMMFPYPSGDLHMGHLKNYTMGDVLARFKKQQGYTVLHPMGWDAFGLPAENAALKFGVHPAEWTFKNIASAKESLRLMGILYDWDREVTTCTPEYYRWNQWIFLKMYEKGLVYRAKGLVNWCPKCQTVLANEQVVDGRCWRHEDTLVEKKELEQWYLRITAYADRLLQDLEQLTGWPEKVKAMQRAWIGRSEGAEIAFPVKGRDVKIPVFTTRPDTLFGATFLVLAPEHPMLLELTAPERRAEVEAYVAAAKQKTELEREALGREKTGVFTGAYAINPATGEEIPIWTADYVLYGYGTGAIMAVPAHDQRDFEFARRFNLPVRVVIQPAEGGLAEPLEAAYEEPGVMVNSGPFDGTPSVEGKGRVIRWLEEKGLGRARVTYRMRDWLISRQRYWGTPIPMIHCEACGIVPVPYEDLPVVLPEIQDVEEIRPKGKSPLEAHPEFYETTCPHCGRPARRDTDTMDTFFDSSWYYLRYADPHNDRLPFDPEKADFWLPVDQYIGGIEHAVLHLLYSRFFTKFLHDIGMVRVEEPFKGLFTQGMVMGWTDYGPVQVEGETVRLSEEARVRLDLESGTLTKAELAKMGAELRAHEDGTTHLWKPAVMSKSLGNGVMVGPFVKEQGADIARITILFAAPPENDMVWTEEGVSGAWRFLNRVWRRFAEDKDALTTLEDAFDPAALSGADRALYRALHRTLKKVGEDTENLRFNTAIAALMELLNALYEYRHKHAPSPVYKRAVRYYLQMLAPFAPHLAEEVWHWLDARSVFEVPWPEVDEDALVEDTFELVVQVNGRVRGRAVLPTNVGEEEAKQAAKAIENVRRHLEGRTIVKEIYVPGKLLNIVVK
>NC_015387.1|WP_148230426.1|1995759_1996194_-|hypothetical-protein
MKKGLAVLLVFGLLLMRVTPALSAGERVEEVFPQQREAIIEVVTPNGLPLSDEDLKDARGQWENVVIGAVAGAAFEIYRQITSSDRVRDWGDVARSAAYGAITGAVGGLGGSVLEAFATGRIGAGFIAGGLAGTIEGHTTRKSR
>NC_015387.1|WP_013704757.1|1997538_1997757_+|cold-shock-protein
MEKGRVKWFNAEKGYGFIERESGGDVFVHFSAINGTGFRTLNEGDVVTFEIKQAAKGPAADNVTVVEPASQY
>NC_015387.1|WP_013704758.1|1997804_1998554_-|hypothetical-protein
MRILLVGPTDVGKTTLSLELARRAARRHGAAYRLDLDVGQGDLPGACTLFRHTPQGAHVLRRALVGRVSPMGAGLELLAASLRLARLVPEPAFLVVDTDGLTEGAFARALRYHQADAVAAREVWVIGAEGLASVFAGREDLKVRVLPPPPGVREKPREERRQRRAARLAAHFAGATHRVLPLPVPDARRLWALLDAKGWLLGYGRVEAYAGGLGLIRTPVRGRVARLERTELAATDAPGVHRLLPGWSP
>NC_015387.1|WP_013704759.1|1998553_1998871_-|(2Fe-2S)-ferredoxin-domain-containing-protein
MKPTYYPTRAHLLLCTGPRCRARGADTVFRYLWDALEREGLAYYKTGGTLRLTESSCLGACCCGPILLAYPAGAWYHGVTVPAALEVARALHEGRDLPETNRFDE
>NC_015387.1|WP_013704760.1|1998867_1999251_-|acyl-CoA-thioesterase
MSEARTLEVVFPEHTNPLGAAFGGFVLGLMDKVGSYAAARHAENPVVTVAVGRVEFKVPIRSGDLLEIVARVTRVGRTSITVAVDVYKERFGGGERTRTLATTGELVYVAVDENGRPTPVPPLEKQA
>NC_015387.1|WP_013704761.1|1999423_2001991_+|ATP-dependent-chaperone-ClpB
MNLEKWTEASRQALAQAQVLAREMGHQQIDLPHLIAVLLREPNGLPSRVLERAGQDPKAALEAAQAALARAPRVEGAQPGQYLSGQLAKAIERAEKLAEEWGDRFVAVDLLLLAAAEAGHPGLPPADQLKQAIQAIRGGRTVESEHTEGTFQALEQYGVDLTRLAQEGKLDPVIGRDEEIRRTVQILLRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKNKRIVALQMGSLLAGAKYRGEFEERLKAVIQETIQSQGEVILFIDELHTIVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDAALERRFQPVLVDEPSVEDTISILRGIKEKYEVHHGVRIADPAIVAAAVLSHRYITDRRLPDKAIDLVDEAASRLRMQLESSPEAIDTLERKKLQLEIEREALKKEKDPDSRAQLEAIENELEQLNAQIAQMRAEWEAEREALQKLREAQKKLDETRTAIEQAERSYDLNKAAELRYGVLPKLEHEVEALSEKLKHARFVRLEVTEEDIAEVVSRWTGIPVAKLLEGEREKLVRLEDELRKRVVGQDEAIVAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDSEEAMVRIDMTEYMEKHAVARLIGAPPGYVGYEEGGQLTEVVRRKPYTVILFDEIEKAHPDVFNILLQILDDGRLTDSHGRVVDFRNTVIILTSNLGSPLILEGIQQGSSYEGIRERVFRVLQEHFRPEFLNRLDEIIVFRPLTKEQIVRIVDLQLQRLQARLQEKRVTLELTPEAKTWLAERGYDPAFGARPLRRVIQREVETPLARMILEGRIPEGARVVARPGEAGLRFEAQTPAQA
>NC_015387.1|WP_013704762.1|2002033_2002738_-|glycerophosphodiester-phosphodiesterase
MPALPFASASRPVLLGHRGAPRVARENTLEAFQAALEAGLDGVEFDVQKTRDGILVVHHDFHVEGAAIAELDWPDLNRRAPWIPRLEAVLELLDAYPEAYANVELKSQPPRSDGREALLARALLAWPGRERAWVSSFDPLALVRLWRETKEIPLGLLYEQQEMLALRSCVHAEAVHPRRDLLDVDQVAALKAQGLAVVVWTVNDLEEARRLLSWGVDALIGDDPEVLLAARRNV

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Crispr_ID: NC_015387_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015387_10

2083555-2085389

TypeI-B

Consensus_repeat	Method
GTTTCAAATCCCAGAAGGAACGGTGAAAAC	PILER-CR
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CRISPRCasFinder
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CRT

27 spacers

cas2,cas1,cas4,cas3,cas7,cas8b1,cas6

The CRISPR arrays of NC_015387_10

>merge|NC_015387|10|2083555-2085389|PILER-CR,CRISPRCasFinder,CRT
GTTTTCACCGTTCCTTCTGGGATTTGAAACACGCGCTCCGCCAACTCTCCCTGATGCTCCGTGAGGGGTTTTCACCGTTCCTTCTGGGATTTGAAACTACAACACGCAACCCCTGATTTGCAACCCCCACCACAATAGTTTTCACCGTTCCTTCTGGGATTTGAAACCCCCAAACCCCTGGTTTTGCGCTACGAAAAACGCCGTTTTCACCGTTCCTTCTGGGATTTGAAACAGGATATCCACAATCGCGTCCTCAGCGCGTTCGGGGTGGTTTTCACCGTTCCTTCTGGGATTTGAAACAAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAACAGTTTTCACCGTTCCTTCTGGGATTTGAAACCGCCGTCAACGTAGCGGATGACTGCCCACGCGGGGAGTTTTCACCGTTCCTTCTGGGATTTGAAACGCGTGGGAATTAGCGTGGGAAAACCAGGACGGGTTCAGTTTTCACCGTTCCTTCTGGGATTTGAAACAAATGAGGTCCCCCCACTGTCGGATCAAAGGGCGGGGTTTTCACCGTTCCTTCTGGGATTTGAAACTCTCGTGGGCTTTGCCAAGGAGAAAAAGGCCGCCTTGGGTTTTCACCGTTCCTTCTGGGATTTGAAACCCTCGAGGCTTACAGTAACCTAGACGGTGTACAAGTTTTCACCGTTCCTTCTGGGATTTGAAACTAGTAACAACCTCAAACGCCTTGTTAGCGATGCCTTGTTTTCACCGTTCCTTCTGGGATTTGAAACCCCCAACGCAACATTATACACCGTCACTGAAACGCAGGTTTTCACCGTTCCTTCTGGGATTTGAAACGCCTCATCCACAATGAATAATAGGTTAGCTCCAGAAGTTTTCACCGTTCCTTCTGGGATTTGAAACCTCGATCCGGCGATCCCCTCGGGGCGGCATGGGCGCCGTTTTCACCGTTCCTTCTGGGATTTGAAACGGCGTGGCTGGCCGAGCGCGGCATGGACATAGAGAGTTTTCACCGTTCCTTCTGGGATTTGAAACTCAAATGGTCCATATTGCGCCGTTCCCGTCCTGGACGTTTTCACCGTTCCTTCTGGGATTTGAAACCTTTCTAGCCGGACGCAGGCGCGGCGGGTCCTGGAAGTTTTCACCGTTCCTTCTGGGATTTGAAACCTGGAGGGACGCATGGAGCGCATGGAGGAACGAGTGGGTTTTCACCGTTCCTTCTGGGATTTGAAACCACTCTAGCCCCCGCTTACCTGAGGAACACCCCCCAGTTTTCACCGTTCCTTCTGGGATTTGAAACAAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAAGTTTTCACCGTTCCTTCTGGGATTTGAAACCATGGAGTGGGTAGAACAAAACGACAACCTATCCAAAGTTTTCACCGTTCCTTCTGGGATTTGAAACTGGCTTCCGTGGTCATCTTCACTACCTCCCTTACACCTGGTTTTCACCGTTCCTTCTGGGATTTGAAACTATACCCCCACCCGGTAGGGTGGGGGGTGGGTTAGCGTGTTTTCACCGTTCCTTCTGGGATTTGAAACCCCAGTCCTCTAATTCACGGTAACTAATGACGTGTTCGTTTTCACCGTTCCTTCTGGGATTTGAAACAAGCGGCTCCTCAGTTACGAAACCACTCTAGCCCCCGCGTTTTCACCGTTCCTTCTGGGATTTGAAACACAGGTTCTCCTTCCCTCTGGTACTCACGGATCTTCTCGTTTTCACCGTTCCTTCTGGGATTTGAAACCCTCACCGCGAAACTCATCATCCAGGAACTAAAAAGTTTTCACCGTTCCTTCTGGGATTTGAAAC

>NC_015387|10|6|2083555-2085389|PILER-CR
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	ACGCGCTCCGCCAACTCTCCCTGATGCTCCGTGAGGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TACAACACGCAACCCCTGATTTGCAACCCCCACCACAATA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCCAAACCCCTGGTTTTGCGCTACGAAAAACGCC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AGGATATCCACAATCGCGTCCTCAGCGCGTTCGGGGTG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAACA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CGCCGTCAACGTAGCGGATGACTGCCCACGCGGGGA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GCGTGGGAATTAGCGTGGGAAAACCAGGACGGGTTCA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAATGAGGTCCCCCCACTGTCGGATCAAAGGGCGGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TCTCGTGGGCTTTGCCAAGGAGAAAAAGGCCGCCTTGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCTCGAGGCTTACAGTAACCTAGACGGTGTACAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TAGTAACAACCTCAAACGCCTTGTTAGCGATGCCTT
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCCAACGCAACATTATACACCGTCACTGAAACGCAG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GCCTCATCCACAATGAATAATAGGTTAGCTCCAGAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTCGATCCGGCGATCCCCTCGGGGCGGCATGGGCGCC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GGCGTGGCTGGCCGAGCGCGGCATGGACATAGAGA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TCAAATGGTCCATATTGCGCCGTTCCCGTCCTGGAC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTTTCTAGCCGGACGCAGGCGCGGCGGGTCCTGGAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTGGAGGGACGCATGGAGCGCATGGAGGAACGAGTGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CACTCTAGCCCCCGCTTACCTGAGGAACACCCCCCA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CATGGAGTGGGTAGAACAAAACGACAACCTATCCAAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TGGCTTCCGTGGTCATCTTCACTACCTCCCTTACACCTG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TATACCCCCACCCGGTAGGGTGGGGGGTGGGTTAGCGT
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCAGTCCTCTAATTCACGGTAACTAATGACGTGTTC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAGCGGCTCCTCAGTTACGAAACCACTCTAGCCCCCGC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	ACAGGTTCTCCTTCCCTCTGGTACTCACGGATCTTCTC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCTCACCGCGAAACTCATCATCCAGGAACTAAAAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC

>NC_015387|10|11|2083555-2085389|CRISPRCasFinder
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	ACGCGCTCCGCCAACTCTCCCTGATGCTCCGTGAGGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TACAACACGCAACCCCTGATTTGCAACCCCCACCACAATA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCCAAACCCCTGGTTTTGCGCTACGAAAAACGCC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AGGATATCCACAATCGCGTCCTCAGCGCGTTCGGGGTG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAACA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CGCCGTCAACGTAGCGGATGACTGCCCACGCGGGGA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GCGTGGGAATTAGCGTGGGAAAACCAGGACGGGTTCA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAATGAGGTCCCCCCACTGTCGGATCAAAGGGCGGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TCTCGTGGGCTTTGCCAAGGAGAAAAAGGCCGCCTTGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCTCGAGGCTTACAGTAACCTAGACGGTGTACAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TAGTAACAACCTCAAACGCCTTGTTAGCGATGCCTT
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCCAACGCAACATTATACACCGTCACTGAAACGCAG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GCCTCATCCACAATGAATAATAGGTTAGCTCCAGAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTCGATCCGGCGATCCCCTCGGGGCGGCATGGGCGCC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GGCGTGGCTGGCCGAGCGCGGCATGGACATAGAGA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TCAAATGGTCCATATTGCGCCGTTCCCGTCCTGGAC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTTTCTAGCCGGACGCAGGCGCGGCGGGTCCTGGAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTGGAGGGACGCATGGAGCGCATGGAGGAACGAGTGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CACTCTAGCCCCCGCTTACCTGAGGAACACCCCCCA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CATGGAGTGGGTAGAACAAAACGACAACCTATCCAAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TGGCTTCCGTGGTCATCTTCACTACCTCCCTTACACCTG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TATACCCCCACCCGGTAGGGTGGGGGGTGGGTTAGCGT
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCAGTCCTCTAATTCACGGTAACTAATGACGTGTTC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAGCGGCTCCTCAGTTACGAAACCACTCTAGCCCCCGC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	ACAGGTTCTCCTTCCCTCTGGTACTCACGGATCTTCTC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCTCACCGCGAAACTCATCATCCAGGAACTAAAAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC

>NC_015387|10|4|2083555-2085389|CRT
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	ACGCGCTCCGCCAACTCTCCCTGATGCTCCGTGAGGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TACAACACGCAACCCCTGATTTGCAACCCCCACCACAATA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCCAAACCCCTGGTTTTGCGCTACGAAAAACGCC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AGGATATCCACAATCGCGTCCTCAGCGCGTTCGGGGTG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAACA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CGCCGTCAACGTAGCGGATGACTGCCCACGCGGGGA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GCGTGGGAATTAGCGTGGGAAAACCAGGACGGGTTCA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAATGAGGTCCCCCCACTGTCGGATCAAAGGGCGGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TCTCGTGGGCTTTGCCAAGGAGAAAAAGGCCGCCTTGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCTCGAGGCTTACAGTAACCTAGACGGTGTACAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TAGTAACAACCTCAAACGCCTTGTTAGCGATGCCTT
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCCAACGCAACATTATACACCGTCACTGAAACGCAG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GCCTCATCCACAATGAATAATAGGTTAGCTCCAGAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTCGATCCGGCGATCCCCTCGGGGCGGCATGGGCGCC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	GGCGTGGCTGGCCGAGCGCGGCATGGACATAGAGA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TCAAATGGTCCATATTGCGCCGTTCCCGTCCTGGAC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTTTCTAGCCGGACGCAGGCGCGGCGGGTCCTGGAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CTGGAGGGACGCATGGAGCGCATGGAGGAACGAGTGG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CACTCTAGCCCCCGCTTACCTGAGGAACACCCCCCA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAAGAATCAAAAGCGCGAAACCCGGAACCCGCAACAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CATGGAGTGGGTAGAACAAAACGACAACCTATCCAAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TGGCTTCCGTGGTCATCTTCACTACCTCCCTTACACCTG
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	TATACCCCCACCCGGTAGGGTGGGGGGTGGGTTAGCGT
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCCAGTCCTCTAATTCACGGTAACTAATGACGTGTTC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	AAGCGGCTCCTCAGTTACGAAACCACTCTAGCCCCCGC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	ACAGGTTCTCCTTCCCTCTGGTACTCACGGATCTTCTC
GTTTTCACCGTTCCTTCTGGGATTTGAAAC	CCTCACCGCGAAACTCATCATCCAGGAACTAAAAA
GTTTTCACCGTTCCTTCTGGGATTTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015387.1\|WP_041658495.1\|2090119_2091181_-\|glucose-1-phosphate-thymidylyltransferase	unknown	unknown	gnl\|CDD\|273500
NC_015387.1\|WP_052297179.1\|2091183_2092509_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225747
NC_015387.1\|WP_013704850.1\|2095138_2095801_+\|HRDC-domain-containing-protein	unknown	unknown	gnl\|CDD\|366173
NC_015387.1\|WP_013704849.1\|2094468_2094918_-\|3D-domain-containing-protein	unknown	unknown	gnl\|CDD\|270620
NC_015387.1\|WP_013704841.1\|2083113_2083377_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015387.1\|WP_169311739.1\|2075134_2075857_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NC_015387.1\|WP_013704838.1\|2079359_2081636_+\|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_015387.1\|WP_013704847.1\|2092580_2093306_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224016
NC_015387.1\|WP_013704839.1\|2081608_2082127_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015387.1\|WP_013704836.1\|2075853_2077746_+\|type-I-B-CRISPR-associated-protein-Cas8b/Csh1	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_015387.1\|WP_013704843.1\|2086714_2087776_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|184694
NC_015387.1\|WP_148230430.1\|2095769_2096585_-\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704840.1\|2082123_2083110_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_015387.1\|WP_041658493.1\|2087785_2090041_-\|endonuclease-MutS2	unknown	unknown	gnl\|CDD\|234750
NC_015387.1\|WP_013704837.1\|2077732_2078656_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|377458
NC_015387.1\|WP_013704833.1\|2073113_2074238_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380636
NC_015387.1\|WP_041658076.1\|2079110_2079356_+\|hypothetical-protein	unknown	unknown	unknown
NC_015387.1\|WP_013704848.1\|2093331_2094459_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226957
NC_015387.1\|WP_013704842.1\|2085507_2086704_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340888
NC_015387.1\|WP_013704834.1\|2074251_2074971_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099

Protein	Function_ID	Function_description	E-value
NC_015387.1\|WP_041658495.1\|2090119_2091181_-\|glucose-1-phosphate-thymidylyltransferase	gnl\|CDD\|273500	TIGR01208, rmlA_long, glucose-1-phosphate thymidylylransferase, long form. The family of known and putative glucose-1-phosphate thymidyltransferase (also called dTDP-glucose synthase) shows a deep split into a short form (see TIGR01207) and a long form described by this model. The homotetrameric short form is found in numerous bacterial species that incorporate dTDP-L-rhamnose, which it helps synthesize, into the cell wall. It is subject to feedback inhibition. This form, in contrast, is found in many species for which it serves as a sugar-activating enzyme for antibiotic biosynthesis and or other, unknown pathways, and in which dTDP-L-rhamnose is not necessarily produced. Alternate name: dTDP-D-glucose synthase.	7.13447e-159
NC_015387.1\|WP_052297179.1\|2091183_2092509_-\|hypothetical-protein	gnl\|CDD\|225747	COG3206, GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane].	4.78726e-24
NC_015387.1\|WP_013704850.1\|2095138_2095801_+\|HRDC-domain-containing-protein	gnl\|CDD\|366173	pfam00570, HRDC, HRDC domain. The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding. Mutations in the HRDC domain cause human disease. It is interesting to note that the RecQ helicase in Deinococcus radiodurans has three tandem HRDC domains.	8.01677e-07
NC_015387.1\|WP_013704841.1\|2083113_2083377_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.65746e-28
NC_015387.1\|WP_169311739.1\|2075134_2075857_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	5.57994e-30
NC_015387.1\|WP_013704838.1\|2079359_2081636_+\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.85037e-41
NC_015387.1\|WP_013704847.1\|2092580_2093306_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224016	COG1091, RfbD, dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane].	9.21248e-60
NC_015387.1\|WP_013704839.1\|2081608_2082127_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.12123e-62
NC_015387.1\|WP_013704836.1\|2075853_2077746_+\|type-I-B-CRISPR-associated-protein-Cas8b/Csh1	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.54517e-128
NC_015387.1\|WP_013704843.1\|2086714_2087776_-\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|184694	PRK14468, PRK14468, 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN.	0
NC_015387.1\|WP_013704840.1\|2082123_2083110_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	4.2108e-167
NC_015387.1\|WP_041658493.1\|2087785_2090041_-\|endonuclease-MutS2	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0
NC_015387.1\|WP_013704837.1\|2077732_2078656_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	7.69504e-66
NC_015387.1\|WP_013704833.1\|2073113_2074238_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380636	cd19981, PBP1_ABC_HAAT-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.	2.55065e-152
NC_015387.1\|WP_013704849.1\|2094468_2094918_-\|3D-domain-containing-protein	gnl\|CDD\|270620	cd14667, 3D_containing_proteins, Non-mltA associated 3D domain containing proteins, named for 3 conserved aspartate residues. This family contains the 3D domain, named for its 3 conserved aspartates, including similar uncharacterized proteins. These proteins contain the critical active site aspartate of mltA-like lytic transglycosylases where the 3D domain forms a larger domain with the N-terminal region. This domain is also found in conjunction with numerous other domains such as the Escherichia coli MltA, a membrane-bound lytic transglycosylase comprised of 2 domains separated by a large groove, where the peptidoglycan strand binds. Domain A is made up of an N-terminal and a C-terminal portion, corresponding to the 3D domain and Domain B is inserted within the linear sequence of domain A. MltA is distinct from other bacterial LTs, which are similar to each other. Escherichia coli peptidoglycan lytic transglycosylase (LT) initiates cell wall recycling in response to damage, during bacterial fission, and cleaves peptidoglycan (PG) to create functional spaces in its wall. PG chains (also known as murein), the major components of the bacterial cell wall, are comprised of alternating beta-1-4-linked N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), and lytic transglycosylases cleave this beta-1-4 bond.	1.79616e-24
NC_015387.1\|WP_013704848.1\|2093331_2094459_-\|ABC-transporter-permease	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	2.00007e-83
NC_015387.1\|WP_013704842.1\|2085507_2086704_-\|MFS-transporter	gnl\|CDD\|340888	cd17330, MFS_SLC46_TetA_like, Eukaryotic Solute carrier 46 (SLC46) family, Bacterial Tetracycline resistance proteins, and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of the eukaryotic proteins MFSD9, MFSD10, MFSD14, and SLC46 family proteins, as well as bacterial multidrug resistance (MDR) transporters such as tetracycline resistance protein TetA and multidrug resistance protein MdtG. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. TetA proteins confer resistance to tetracycline while MdtG confers resistance to fosfomycin and deoxycholate. The Solute carrier 46 (SLC46) family is composed of three vertebrate members (SLC46A1, SLC46A2, and SLC46A3), the best-studied of which is SLC46A1, which functions both as an intestinal proton-coupled high-affinity folate transporter involved in the absorption of folates and as an intestinal heme transporter which mediates heme uptake. MFSD10 facilitates the uptake of organic anions such as some non-steroidal anti-inflammatory drugs (NSAIDs) and confers resistance to such NSAIDs. The SLC46/TetA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.15309e-50
NC_015387.1\|WP_013704834.1\|2074251_2074971_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	2.60289e-59

>NC_015387.1|WP_013704841.1|2083113_2083377_+|CRISPR-associated-endonuclease-Cas2
MYVIMAYDVNVERVVKVLHTGRRYLTWVQNSVLEGELTPALFERLKADIAKIIDPNQDAVRFYVIKRTACFEKEFLGHSKNEPGQIL
>NC_015387.1|WP_013704840.1|2082123_2083110_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKPIYIFSSGRLTRRQHTLFLETEEGKRPIPIQQVSEIYAFGELELNKRLLEFLTQHRVPMHFFNRYGYYVGTYYPREFLSSGHLTLKQAEHYLNPQLRLDLARRFVRGALWNLVRVLAYYARRDAELEAPIRTIEDLQEAVMETNSIPELMALEGNAREVYYHAWEHILPDSFTLTTRTRRPPTTPANALVSFLNSLLYTATLAQIYQTHLDPRIGYLHETNYRRHTLNLDVAEVFKPTYVDRLIFRLVNRKQLSQKHFLKEGGGVFLNDAGRKTVLKEWEDFLQSTYKHPKLGRHVSWRTTLRLELYKLEKHLLGDRPYEPFKHRG
>NC_015387.1|WP_013704839.1|2081608_2082127_+|CRISPR-associated-protein-Cas4
MGAQGPVPVSGTLIWYYAICPREAWLMGHAIEPWQDHERLALGRLLHETAYPKARREITLPGMRIDLIRQEGTALVIGEVKLSRGAHHAHRLQLGYYLMRLEAEGLQAKGELRYPHERRVQSLTLDDTLRQDVQAALEGLHQLLTQPQPPALERNPYCASCAYYGFCWVEEA
>NC_015387.1|WP_013704838.1|2079359_2081636_+|CRISPR-associated-endonuclease-Cas3''
MLEARPGEPLLEHLVRVAELAERWAPPQLKAEARIAGRVHDLFKATPWFQRYLHAPPKEQAQLKAQYGERLHHAWAGAVFGAFVSAQRGHDALAVFLAVACHHGHLKTPTALLPNKRDLLTGRFTRLDALEAQIQAVLGWEEGAKLLEALDLKAAFLEFARTDKPRFLNDLRQRFAVTRGRYWAVTWLFSALIDADKHLAAGTPSPERVPLPERVPEPFLNEVKRGAPIDPLRERLYRAVQQRIREAPLDHLFPAALTLTAPTGAGKTLTLLNAALELRTRVQAERGHTPRIVYALPYINLIEQNHAVFEAAMRHAGIPAEHALLAHHHLSEARDEDDLTETEHRLLLTESWEAELIVTTFVQVIETLYGTHNRTLKKLHRLLNHTILILDEVQALPAEHWPLLRRLLTEFVKHGNTVILATATQPALLQDALELAPHLPDWPTRVHIRRAETPPTTPPNRSRLIVANTVARSLELYAQQKALGGEVHYLSTNLTPHDRAQRIALLKQKLPHTPLTLVATPIVEAGLDLDFREGWRELGPVDAVIQVAGRINRSGNRPPEPLYLLPETNMARVYGRVLAELARSFFNTFTEGSDHALTAHLPPYFAALEARLASAQATGFIEAMTHHRFCRSGYPRRCRDGCGPTNPEGCDVCCFSLIQEEMIRIPIFIEQNDEASEALAELEAALKEPDPTRKRARLRRVRPKLARYTINPIARIAAKNLPSPLFGREDYRLVRREELEAYYDEETGFVWELKDQFL
>NC_015387.1|WP_041658076.1|2079110_2079356_+|hypothetical-protein
MDGQLEPGLHGPLWGAFMIEALEELRGPGRILHDRYPLRLAPDRTLVLAKDLGLEAEGRPVEMRYNGPVFVSGERAFALVG
>NC_015387.1|WP_013704837.1|2077732_2078656_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MKLLDGEILFLYDAKMTNPNGDPDEENKPRMDYATSRALVSDVRLKRYLRDYWLSQGRDVWVRTLNERTVSADQRLRDLQETHQREAKDREFVPWLLDRLIDVRLFGATMPIKARENESRGSGLTFTGPVQFTWGYSLHPVEIMDSSTISSTFAGRENEHGTFGKDWRIYYGLIAFMGRVSTRRGQTTHLQETDLDALEEALLKAIPAEAVTRSKFGQTPRLYLHVRYREGAYPFPPVGDLRDQVRFLPSEGLEPRKVRAVGDYRLDLTPLTEALRPHASRIEEVRLWVHPELRVQGLEGLPHLHTL
>NC_015387.1|WP_013704836.1|2075853_2077746_+|type-I-B-CRISPR-associated-protein-Cas8b/Csh1
MIRELTRLGEAVLANDEAGVLEALIEDIGNLKPKRGNAPHLVVLNLSSEGRLEWRTEVLDPPRAEAYLWLGNPRANAPKVRVTTSNLAYLLGQTFYALTEDADTPPELRAYLERVFPKLFWHDPEARGGKRKYAYLLDAQKLGLDVDWPALRDLPPKQRPAQLAKALTALFDLPKQGVLYTLAIDGTPLAQLPAYRAYMLRKLVGELFEDAKDGVCHACGARTAVNAKFTHFKIKLFINDKLSFAYGLDAENWTKNHALCQRCYTRALSGERYLERHLSTRVLGTETLIVPHLDPTPLSQETLDALSALLRETTSSLERLESVPELLDRLEPHTRLPQLTLLFIRRAQSAVKLIEAVPEVEPSRIEAVLRAIGEANRHANTLFGAPRTGAWLPGLAALLDVLPLKHEQGAPHAAPALRVLRQILLGEPLSRPRLLREFLQVLRYIHRNNPGIYATRSCRAPGGYCPEIEDAIPRMTAFLHFLEALEMLEVNPMELDTKLPGYTEPIQTLGLDAPRTALFLLGVLLARVASEQYKRGKSKPVLEKVGYQGMPLEKVRRFALELFEKLTEYRRLDASSEVVFATATELLAQPRPWPLSDEENAFYILLGYGFETRRILNAGRKEKEDDHEAA
>NC_015387.1|WP_169311739.1|2075134_2075857_+|CRISPR-associated-endoribonuclease-Cas6
MHQVTVWLRPSEPVLLPFTYREELQGLVYRRLPEKLSRWLHDEGLPTQRGRFKPFVFSRLTGKLRPQPAFKALLATGPVAFHLASPLPEVAQGFAQGLLTQPRVRLHKARFTLEELTLSEVPLPQTPALLEARAPITVYRKENGQRRYYTPFEPEFAALVLENLRAKAQALNRETSGTLHLEPVGVTPRHKKIERFRRMIIEGWMGRYRLTAPPEILWVALTAGLGALGSQGFGYVEVVS
>NC_015387.1|WP_013704834.1|2074251_2074971_-|GntR-family-transcriptional-regulator
MKYKRIKDQLLQAIRAGRYTHALPSEPALARQYGVSRMTARRALEELVREGYALRVPGKGTFLAERRFSQGFFRVRPFYAYAAAQGARPATRLVSAGFAEAPEPVAQKLGTREAVCVRRMRYLDGTPVLFETRYLRRDLCAAVLEEDLEAESLHELLVQKLGLPLTRVWQRLEASELVGELARWFGLPSGFPAFRMERVTFTFETPVTWVEYFMRGDRYVFEDTFSPQAEAAGVGERAE
>NC_015387.1|WP_013704833.1|2073113_2074238_-|ABC-transporter-substrate-binding-protein
MRQVFMALAVLLGVALAQAPVKVGVLAPLSGFAAADGRSALTGIELAVEEINAQGGLLGRPVELVVYDDQADPKQAVNFARRLVELDKVAFVIGASYSGASLAAAPVVNEAGIPFIAAYAVAPDITRDKPYVFRMGLLGTVQGRVGAELAHELGAKRVAILTIQNDFGRALEAGFRERAQVLGLEIVYRDTYPLGNKNFTPILARLRAARPEVLYASAYFSEAANLVRQVRSLGMEVRVIGQEGYDSPKFIELAGDAAEGVLITTTLDRDSTDPAVQRFLEAYRERAGIPADMVGASGYAAMQVMALAAQRAGGLDGEALREALAQLEEVETVVGHVFYWTEDGDPVKTATVQEVREGRFRRFMKFDRIEVLKP
>NC_015387.1|WP_013704842.1|2085507_2086704_-|MFS-transporter
MGPLALLFLSLFNSILGLSVLFPILAPLARELGLSEVQVGLFSTGYALMQFVMSPYWGRQSERVGRKPVLLVGILGFALSFYLFAIVAQLGFAGRLGPGVLFGLLLAARVLGGTFSSATLPTAQAYVADVTGRNERTAGMALIGAAFGLGVIFGPAIGAGLAGISLLAPIYFSASLALLNAWFVWWKLPEPQRRVGAEAAGALRPTDPRIQPLLVLGFAVSLASVALEQTVAFYFQDRLGLDATGTARAVGTALVVYGLVAVFVQGVLVRKYQWPPRVLLWVGVPAALAGFVLFIFAHGFAVLTLALVLQGFGQGLAMPGVTAALSLAVGEGEQGSVAGLGSAAQALGRMLGPVAGTGLYEFRPEYPYVFSASLLGLALFLLAVNPRVRQALEEHPGA
>NC_015387.1|WP_013704843.1|2086714_2087776_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MREPAEWNAHLPLALGDERRPILEPEPEDLPGEGYRKRQIAHWLYAWGVREFDEMTDLPRALRAELAHTWRISEFSLVQAFPSADGSTKYLYTLHDGRQTEAVYMPYKDRRTICISSMVGCPAGCTFCATGQMRFGRNLTAPEILDQLLAAAYHQGISPREIRNVVLMGMGEPLLNLTNVLKAVRRMIHKQALAMSPRRITLSTVGIPRGIYRLAEEDVGVKLALSLHAPDDETRRRIIPTAHRYAIEEIMDAVRHYYRRTKRRVTLEYTLLRGVNDHLWQAKMLAKHTRGLTAHVNLIPFNPWEGAPHEGSSREQIRRFAAVLEAAGIPVSVRWSRGRDVGAACGQLALRTP
>NC_015387.1|WP_041658493.1|2087785_2090041_-|endonuclease-MutS2
MRDARTALEFDRVRAALAERAATALGVERAQALEPYPTPAEAQAFQAAVAEALLVPYRLGGIRDLRPLLQRAREGRRLEGLELVEAAHTLSAAAELKRHLLEAETEHLAGLAARVGEHLLFRRRVAEALEEDGRVKDHATPKLRQIRRRMEPLRAQIQDRLYAVMDAHPEAVQERFITLRRDRYVIPIKAHLQHQVTGIVLDQSASGATVFLEPASVVPLNNELAKLRLEEEAEVQRVLFELTQALAADPEVDRTLEALAALDLVRAAASLAEDWRLVRPRWGEAGTYRLEGLFHPLIVNCVPNDLELDADRRLLLITGPNMGGKTVLLKSLGLAVLMAQSGLFVPARAAELPWVDALLVDIGDEQSLEHSLSTFAAHLVRLEAVLQHASPRALVLIDELGSGTDPMEGAALSQAVLEALLERGARGVITTHLTPLKAFAMEREGVLNASMAFDLERLEPTYRLVLGVPGRSYALAVARQLGFPEAVLKRAEALLGPEGRELELLLERIEAERRALEAELAQARAARAEAEALRAELEARLARIEAERQERLEAARAEADRLLKEVHERIRSLREQARKGESAKRDALRTVMQLRQKGRPEPKRPRLEGLKPGMTVEVPSYRKTGTVVRVDGEEAVVQIGVLKVSVPTAELRPRGEDAPRPKQAVVVKSGFEPELNVRGLTAVEAVEAVHDFISEALALKETPVRILHGKGTGALRRAIRDALKRDKRVASFHDAMPYEGGHGVTVVHLKV
>NC_015387.1|WP_041658495.1|2090119_2091181_-|glucose-1-phosphate-thymidylyltransferase
MKGLILAAGRGTRLRPLTHTRPKPAIRVAGRPIIHYAVENLTRSGITEIGVVVSPDTAKDIRLALNGFKDARLTYIVQEESQGLAHAVRVAREWLGDSPFVMYLGDNLFEHGVARFVKAFQQDEADAVIALVPVENPQQFGVAVVEGGRIVRLLEKPQNPPTNLAVAGVYVFTPEIHEIIAGLEPSARGEYEITDAIQGLIDRGRAVRGVTVEGWWKDTGRPHDLLDANRLLLEGLEPRVEGLVSGSRVTGRVVIEPGASVLDSTILGPALIASGAVVESAFIGPFTSVGPGAQVRRAEVEFSILEDKAVVEDVNLRIQECILGVGSKVTTRKGLPKAHKLVLGDKSVVEVGE
>NC_015387.1|WP_052297179.1|2091183_2092509_-|hypothetical-protein
MPEATSYPDEITLRDLVEVLKRRWRLLVAVPALAVAAAAAYLILWAKPAYEAAATVSISPLQVQARLEEKIQVEDQPFIGFSGYRSIAYSEPVLREVLAGLRQQDSMPEAWRDREDGELLESLADSLKLKDLSPKNAQAGLIVEHRAREGDPRLAAEIANLWVDATLRRVNAVPVERTRAVLEVLEERLSESEARYRKAQQAWEAFQRTSTLEQDQAALSAFTNERVRLEGELAQLRQNLAAIRARIQAVQAQLEGEPERLSLERSVFADPLATTLLGQRGVQEAAELRLVDQELNPVYVRLQQTLVDARTEEARLTAREAALQERLEELEARIADLKARVAEAQVRAQQVQEQLDLARSEYIALAQKRNDLRIEAASVQRSLAQVLAPAYPMFDPVAPKTALILALALVLGGMLALVWAFVADALQPAPEGANASHTMKA
>NC_015387.1|WP_013704847.1|2092580_2093306_+|NAD(P)-dependent-oxidoreductase
MRLLVTGSTGRMGRTLLPLLPTEWEVIAPRRPAVDLTRPETLDALFAAHQPEVVLHLAAYTDVARAEREREVCWRVNVEGTRALARRAPGWFVHLSTDYVFDGERGMYREEDLPNPKNFYALSKTVGEEAARQAPRPLIVRTSFKTAPWPYPRAFVDQFTSADYVDVIARELLVLLRNLERLPRAVEVLHIATERKSVYDLARRRTPSVQPMQRAEAPVYIPPDVSLDTTRWQQLKAGWGS
>NC_015387.1|WP_013704848.1|2093331_2094459_-|ABC-transporter-permease
MRLVLFLARKHLTYRRTQSLITVLGVAAGVMVLTTALSLTNGFTSALLHATLRAIPHITLFAFDPQDAPPPHHPEIQAQTPFLPAKVLLTRRAQAGRNAGADFATLLGVGEDAPAVYPGLGLEALEPGRVVLGAALAEALGALPGDRLFAVSVNQRRHELVVAGTFTTGNYLIDSSFAFTTLEDVRTLLELPGAIGGYHLRLEDPERARAVARALTQSGVFWAQTWQDANRTLIEQLALQKRVIGIVVFLIVVVAALGIANVLVLVVVEKTADIAILRVLGASAAQVAAVFALEGVLLGGLGVVLGDLLGLGLSHYFRLRPLEIPGELYFITRLPVEIRALDFAWVSALAFGTVLLASLLPLRRALRVKPGEVLR
>NC_015387.1|WP_013704849.1|2094468_2094918_-|3D-domain-containing-protein
MIHTAHPILRRFAILLGLSLLILPAKAEGPKVLILKATAYTSSVRETDATPFITATGARTRYGIIAVSRDLLQTDLPYGSLVKLEDLGRWEDGAEKGKYNPMLEGILFVVEDTMNRRKRQQIDIWMPDRALALKWGVRRVKLTIVRYGR
>NC_015387.1|WP_013704850.1|2095138_2095801_+|HRDC-domain-containing-protein
MPQRTLGIVLASAGLVYLTLLNPWTPGWPWGLAGGLGFLVLYRRSKVRDALLAGALFFGWGVGAAFADWLDYQALKLLGLGLGFGLYGWLENAAWGLWTAAGLAGIGALVFLWEIGTAVWLALALVGAGAWFVLKGEAAPPTLPPAREALYKHLYAWRVAQARREERSSAEVLPNRLVARIVQENPQDPEALREILGEERAAYTEAIWELLKARDSSPTG
>NC_015387.1|WP_148230430.1|2095769_2096585_-|hypothetical-protein
MRGWILGALALLLAACTVQLSPPIDGVLSVDGAAITIDNLPPGEMRQYRIDVEQTGTIRVQAVPEAVPQASQLELTVFNRDFVPLAKAVSRYWFGIPQVTLLGITPTPIDAYRINLKVQAGDVFFVRVANRGTLAERVEVSVASFTPRSDRSDGGTLRDGVPVTGAIEFLGEFDTYTIDPNLPSGRFLHLDYSGPIDLVAFVFASTDTGEPPLAVLEPQKNNCVPVQAGTFVLVRDRSSGSTVEGPGARAGFDEPGSGQYTLSLLGSCPVP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_015387_2	2.1\|274081\|39\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274081-274119	39	NC_015387.1	2165154-2165192	0	1.0
NC_015387_2	2.2\|274157\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274157-274191	35	NC_015387.1	2000583-2000617	0	1.0

1. spacer 2.1|274081|39|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to position: 2165154-2165192, mismatch: 0, identity: 1.0

caggcgcctaccacgggccggtcctcgtggtctggggca	CRISPR spacer
caggcgcctaccacgggccggtcctcgtggtctggggca	Protospacer
***************************************

2. spacer 2.2|274157|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to position: 2000583-2000617, mismatch: 0, identity: 1.0

acgaggccgcgagccgcctccgcatgcagctcgag	CRISPR spacer
acgaggccgcgagccgcctccgcatgcagctcgag	Protospacer
***********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015387_6	6.23\|961065\|33\|NC_015387\|PILER-CR	961065-961097	33	MH825706	Streptomyces phage Microdon, complete genome	34532-34564	4	0.879
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MH825706	Streptomyces phage Microdon, complete genome	34532-34563	4	0.875
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN871446	UNVERIFIED: Serratia phage KpLz-2_45, complete genome	220038-220069	5	0.844
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN871452	UNVERIFIED: Serratia phage KpZh_1, complete genome	41771-41802	5	0.844
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN871447	UNVERIFIED: Serratia phage KpLz_1_41, complete genome	288416-288447	5	0.844
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN871449	UNVERIFIED: Serratia phage KpXa_1, complete genome	273771-273802	5	0.844
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN871453	UNVERIFIED: Serratia phage KpZh_LPS_45, complete genome	208339-208370	5	0.844
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN871451	UNVERIFIED: Serratia phage KpYy_2_45, complete genome	20217-20248	5	0.844
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN871448	UNVERIFIED: Serratia phage KpSz_1, complete genome	20305-20336	5	0.844
NC_015387_6	6.11\|960333\|33\|NC_015387\|PILER-CR	960333-960365	33	NZ_LR134461	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence	134749-134781	6	0.818
NC_015387_6	6.29\|961431\|33\|NC_015387\|PILER-CR	961431-961463	33	AP014720	Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8	8075-8107	6	0.818
NC_015387_6	6.67\|960334\|32\|NC_015387\|CRISPRCasFinder,CRT	960334-960365	32	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	112556-112587	6	0.812
NC_015387_6	6.67\|960334\|32\|NC_015387\|CRISPRCasFinder,CRT	960334-960365	32	NZ_LR134461	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence	134750-134781	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	NC_017533	Pantoea ananatis AJ13355 plasmid pEA320, complete sequence	28709-28740	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	NC_016817	Pantoea ananatis LMG 5342 plasmid pPANA10, complete sequence	81912-81943	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	NZ_CP020944	Pantoea ananatis strain PNA 97-1R plasmid unamed1, complete sequence	81977-82008	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	NZ_CP014208	Pantoea ananatis strain R100 plasmid, complete sequence	295607-295638	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	NC_017553	Pantoea ananatis PA13 plasmid PAGR_p, complete sequence	82077-82108	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	CP054909	Pantoea ananatis strain FDAARGOS_680 plasmid unnamed1, complete sequence	152938-152969	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	NZ_CP022429	Pantoea ananatis strain YJ76 plasmid p_unamed1	200810-200841	6	0.812
NC_015387_6	6.72\|960638\|32\|NC_015387\|CRISPRCasFinder,CRT	960638-960669	32	NZ_CP035036	Pantoea ananatis strain NN08200 plasmid unnamed2, complete sequence	184638-184669	6	0.812
NC_015387_6	6.85\|961432\|32\|NC_015387\|CRISPRCasFinder,CRT	961432-961463	32	AP014720	Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8	8076-8107	6	0.812
NC_015387_6	6.98\|962225\|33\|NC_015387\|CRISPRCasFinder,CRT	962225-962257	33	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	470794-470826	6	0.818
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013597	Rhizobium sp. N741 plasmid pRspN741b, complete sequence	70900-70931	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013501	Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence	71260-71291	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013507	Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence	70900-70931	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013518	Rhizobium sp. N113 plasmid pRspN113a, complete sequence	71260-71291	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013491	Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence	71260-71291	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013513	Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence	70654-70685	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013496	Rhizobium sp. N621 plasmid pRspN621a, complete sequence	71260-71291	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013591	Rhizobium sp. N871 plasmid pRspN871a, complete sequence	71260-71291	6	0.812
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013603	Rhizobium sp. N731 plasmid pRspN731b, complete sequence	70654-70685	6	0.812
NC_015387_2	2.2\|274157\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274157-274191	35	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	127962-127996	7	0.8
NC_015387_2	2.2\|274157\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274157-274191	35	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	372289-372323	7	0.8
NC_015387_2	2.2\|274157\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274157-274191	35	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	493058-493092	7	0.8
NC_015387_2	2.2\|274157\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274157-274191	35	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	633082-633116	7	0.8
NC_015387_6	6.11\|960333\|33\|NC_015387\|PILER-CR	960333-960365	33	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	112556-112588	7	0.788
NC_015387_6	6.22\|961003\|34\|NC_015387\|PILER-CR	961003-961036	34	MK291445	Paracoccus phage vB_PyeM_Pyei1, complete genome	27250-27283	7	0.794
NC_015387_6	6.42\|962224\|34\|NC_015387\|PILER-CR	962224-962257	34	NZ_CP045548	Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence	470793-470826	7	0.794
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013597	Rhizobium sp. N741 plasmid pRspN741b, complete sequence	70900-70932	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013501	Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence	71260-71292	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013507	Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence	70900-70932	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013518	Rhizobium sp. N113 plasmid pRspN113a, complete sequence	71260-71292	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013491	Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence	71260-71292	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013513	Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence	70654-70686	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013496	Rhizobium sp. N621 plasmid pRspN621a, complete sequence	71260-71292	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013591	Rhizobium sp. N871 plasmid pRspN871a, complete sequence	71260-71292	7	0.788
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP013603	Rhizobium sp. N731 plasmid pRspN731b, complete sequence	70654-70686	7	0.788
NC_015387_6	6.58\|959784\|32\|NC_015387\|CRISPRCasFinder,CRT	959784-959815	32	NZ_CP033971	Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence	74993-75024	7	0.781
NC_015387_6	6.60\|959906\|32\|NC_015387\|CRISPRCasFinder,CRT	959906-959937	32	NC_018685	Bacillus thuringiensis MC28 plasmid pMC95, complete sequence	37794-37825	7	0.781
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	2822-2853	7	0.781
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP032314	Pannonibacter phragmitetus BB plasmid p.BB_2, complete sequence	80576-80607	7	0.781
NC_015387_6	6.78\|961004\|33\|NC_015387\|CRISPRCasFinder,CRT	961004-961036	33	MK291445	Paracoccus phage vB_PyeM_Pyei1, complete genome	27250-27282	7	0.788
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	108481-108512	7	0.781
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	1005325-1005356	7	0.781
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	1453797-1453828	7	0.781
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MH229864	Streptomyces phage UNTPL, complete genome	35063-35094	7	0.781
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NZ_CP010590	Phaeobacter gallaeciensis strain P11 plasmid pP11_b, complete sequence	55774-55805	7	0.781
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NZ_CP010675	Phaeobacter gallaeciensis strain P75 plasmid pP75_b, complete sequence	52284-52315	7	0.781
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NC_023148	Phaeobacter gallaeciensis DSM 26640 plasmid pGal_B134, complete sequence	55865-55896	7	0.781
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NZ_CP010791	Phaeobacter gallaeciensis strain P63 plasmid pP63_x_draft, complete sequence	52284-52315	7	0.781
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NZ_CP010631	Phaeobacter inhibens strain P78 plasmid pP78_b, complete sequence	52284-52315	7	0.781
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NZ_CP010619	Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_b, complete sequence	94481-94512	7	0.781
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NZ_CP010638	Phaeobacter gallaeciensis strain P73 plasmid pP73_b, complete sequence	52284-52315	7	0.781
NC_015387_6	6.98\|962225\|33\|NC_015387\|CRISPRCasFinder,CRT	962225-962257	33	NZ_CP032350	Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence	175604-175636	7	0.788
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	290884-290915	7	0.781
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NC_007764	Rhizobium etli CFN 42 plasmid p42c, complete sequence	43556-43587	7	0.781
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020908	Rhizobium etli strain NXC12 plasmid pRetNXC12b, complete sequence	54151-54182	7	0.781
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NC_021907	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1b, complete sequence	43552-43583	7	0.781
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_LR134466	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 24, complete sequence	76161-76192	7	0.781
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP006987	Rhizobium sp. IE4771 plasmid pRetIE4771a, complete sequence	192049-192080	7	0.781
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	728752-728783	7	0.781
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	981615-981646	7	0.781
NC_015387_7	7.9\|1466552\|37\|NC_015387\|CRISPRCasFinder	1466552-1466588	37	NZ_CP019063	Rahnella sp. ERMR1:05 plasmid unnamed1, complete sequence	517445-517481	7	0.811
NC_015387_7	7.51\|1467555\|37\|NC_015387\|PILER-CR	1467555-1467591	37	NZ_CP043619	Rhodobacteraceae bacterium SH-1 plasmid p1, complete sequence	44466-44502	7	0.811
NC_015387_7	7.78\|1467556\|36\|NC_015387\|CRT	1467556-1467591	36	NZ_CP043619	Rhodobacteraceae bacterium SH-1 plasmid p1, complete sequence	44466-44501	7	0.806
NC_015387_2	2.2\|274157\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274157-274191	35	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1370845-1370879	8	0.771
NC_015387_2	2.2\|274157\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274157-274191	35	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	194823-194857	8	0.771
NC_015387_6	6.8\|960150\|33\|NC_015387\|PILER-CR	960150-960182	33	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	33002-33034	8	0.758
NC_015387_6	6.11\|960333\|33\|NC_015387\|PILER-CR	960333-960365	33	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	17443-17475	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	NC_016817	Pantoea ananatis LMG 5342 plasmid pPANA10, complete sequence	81911-81943	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	NZ_CP020944	Pantoea ananatis strain PNA 97-1R plasmid unamed1, complete sequence	81976-82008	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	NC_017553	Pantoea ananatis PA13 plasmid PAGR_p, complete sequence	82076-82108	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	NZ_CP022429	Pantoea ananatis strain YJ76 plasmid p_unamed1	200809-200841	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	NC_017533	Pantoea ananatis AJ13355 plasmid pEA320, complete sequence	28709-28741	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	NZ_CP014208	Pantoea ananatis strain R100 plasmid, complete sequence	295607-295639	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	CP054909	Pantoea ananatis strain FDAARGOS_680 plasmid unnamed1, complete sequence	152938-152970	8	0.758
NC_015387_6	6.16\|960637\|33\|NC_015387\|PILER-CR	960637-960669	33	NZ_CP035036	Pantoea ananatis strain NN08200 plasmid unnamed2, complete sequence	184638-184670	8	0.758
NC_015387_6	6.20\|960881\|33\|NC_015387\|PILER-CR	960881-960913	33	NZ_CP016453	Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence	689426-689458	8	0.758
NC_015387_6	6.23\|961065\|33\|NC_015387\|PILER-CR	961065-961097	33	NZ_LR134454	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence	9692-9724	8	0.758
NC_015387_6	6.28\|961370\|33\|NC_015387\|PILER-CR	961370-961402	33	NZ_CP044989	Deinococcus sp. AJ005 plasmid p380k, complete sequence	250117-250149	8	0.758
NC_015387_6	6.31\|961553\|33\|NC_015387\|PILER-CR	961553-961585	33	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1271375-1271407	8	0.758
NC_015387_6	6.39\|962041\|33\|NC_015387\|PILER-CR	962041-962073	33	NZ_CP020716	Cnuibacter physcomitrellae strain XA(T) plasmid unnamed1, complete sequence	110372-110404	8	0.758
NC_015387_6	6.40\|962102\|33\|NC_015387\|PILER-CR	962102-962134	33	CP054922	Streptomyces sp. NA03103 plasmid unnamed2, complete sequence	104527-104559	8	0.758
NC_015387_6	6.41\|962163\|33\|NC_015387\|PILER-CR	962163-962195	33	NZ_CP010590	Phaeobacter gallaeciensis strain P11 plasmid pP11_b, complete sequence	55774-55806	8	0.758
NC_015387_6	6.41\|962163\|33\|NC_015387\|PILER-CR	962163-962195	33	NZ_CP010675	Phaeobacter gallaeciensis strain P75 plasmid pP75_b, complete sequence	52284-52316	8	0.758
NC_015387_6	6.41\|962163\|33\|NC_015387\|PILER-CR	962163-962195	33	NC_023148	Phaeobacter gallaeciensis DSM 26640 plasmid pGal_B134, complete sequence	55865-55897	8	0.758
NC_015387_6	6.41\|962163\|33\|NC_015387\|PILER-CR	962163-962195	33	NZ_CP010791	Phaeobacter gallaeciensis strain P63 plasmid pP63_x_draft, complete sequence	52284-52316	8	0.758
NC_015387_6	6.41\|962163\|33\|NC_015387\|PILER-CR	962163-962195	33	NZ_CP010631	Phaeobacter inhibens strain P78 plasmid pP78_b, complete sequence	52284-52316	8	0.758
NC_015387_6	6.41\|962163\|33\|NC_015387\|PILER-CR	962163-962195	33	NZ_CP010619	Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_b, complete sequence	94481-94513	8	0.758
NC_015387_6	6.41\|962163\|33\|NC_015387\|PILER-CR	962163-962195	33	NZ_CP010638	Phaeobacter gallaeciensis strain P73 plasmid pP73_b, complete sequence	52284-52316	8	0.758
NC_015387_6	6.42\|962224\|34\|NC_015387\|PILER-CR	962224-962257	34	NZ_CP032350	Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence	175603-175636	8	0.765
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	290884-290916	8	0.758
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NC_007764	Rhizobium etli CFN 42 plasmid p42c, complete sequence	43556-43588	8	0.758
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP020908	Rhizobium etli strain NXC12 plasmid pRetNXC12b, complete sequence	54151-54183	8	0.758
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NC_021907	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1b, complete sequence	43552-43584	8	0.758
NC_015387_6	6.58\|959784\|32\|NC_015387\|CRISPRCasFinder,CRT	959784-959815	32	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	62203-62234	8	0.75
NC_015387_6	6.62\|960028\|32\|NC_015387\|CRISPRCasFinder,CRT	960028-960059	32	CP041517	Bacillus aryabhattai strain KNU10 plasmid unnamed1, complete sequence	63912-63943	8	0.75
NC_015387_6	6.64\|960151\|32\|NC_015387\|CRISPRCasFinder,CRT	960151-960182	32	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	33002-33033	8	0.75
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	1624774-1624805	8	0.75
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1482397-1482428	8	0.75
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	227125-227156	8	0.75
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP020372	Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence	370760-370791	8	0.75
NC_015387_6	6.67\|960334\|32\|NC_015387\|CRISPRCasFinder,CRT	960334-960365	32	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	17444-17475	8	0.75
NC_015387_6	6.67\|960334\|32\|NC_015387\|CRISPRCasFinder,CRT	960334-960365	32	NZ_CP018075	Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence	97205-97236	8	0.75
NC_015387_6	6.76\|960882\|32\|NC_015387\|CRISPRCasFinder,CRT	960882-960913	32	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	918553-918584	8	0.75
NC_015387_6	6.76\|960882\|32\|NC_015387\|CRISPRCasFinder,CRT	960882-960913	32	NZ_CP016453	Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence	689427-689458	8	0.75
NC_015387_6	6.78\|961004\|33\|NC_015387\|CRISPRCasFinder,CRT	961004-961036	33	MK937595	Streptomyces phage Dubu, complete genome	34300-34332	8	0.758
NC_015387_6	6.78\|961004\|33\|NC_015387\|CRISPRCasFinder,CRT	961004-961036	33	MG945161	UNVERIFIED: Microviridae sp. isolate 405-1507, complete genome	3381-3413	8	0.758
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_LR134454	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence	9693-9724	8	0.75
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP036221	Mycobacterium avium subsp. hominissuis strain mc2 2500 plasmid unnamed1, complete sequence	20725-20756	8	0.75
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP040253	Mycobacterium avium subsp. hominissuis strain 101115 plasmid pMARIA, complete sequence	5813-5844	8	0.75
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP040245	Mycobacterium avium subsp. hominissuis strain 101034 plasmid pMARIA, complete sequence	19707-19738	8	0.75
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP040249	Mycobacterium avium subsp. hominissuis strain 101174 plasmid pMARIA, complete sequence	15733-15764	8	0.75
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MN103533	Mycobacterium phage Weirdo19, complete genome	40393-40424	8	0.75
NC_015387_6	6.81\|961188\|32\|NC_015387\|CRISPRCasFinder,CRT	961188-961219	32	NZ_CP039918	Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence	16472-16503	8	0.75
NC_015387_6	6.81\|961188\|32\|NC_015387\|CRISPRCasFinder,CRT	961188-961219	32	NZ_CP039905	Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence	16472-16503	8	0.75
NC_015387_6	6.81\|961188\|32\|NC_015387\|CRISPRCasFinder,CRT	961188-961219	32	NZ_CP039909	Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence	211330-211361	8	0.75
NC_015387_6	6.83\|961310\|32\|NC_015387\|CRISPRCasFinder,CRT	961310-961341	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1512267-1512298	8	0.75
NC_015387_6	6.83\|961310\|32\|NC_015387\|CRISPRCasFinder,CRT	961310-961341	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	442367-442398	8	0.75
NC_015387_6	6.84\|961371\|32\|NC_015387\|CRISPRCasFinder,CRT	961371-961402	32	NZ_CP044989	Deinococcus sp. AJ005 plasmid p380k, complete sequence	250118-250149	8	0.75
NC_015387_6	6.87\|961554\|32\|NC_015387\|CRISPRCasFinder,CRT	961554-961585	32	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1271376-1271407	8	0.75
NC_015387_6	6.95\|962042\|32\|NC_015387\|CRISPRCasFinder,CRT	962042-962073	32	NZ_CP020716	Cnuibacter physcomitrellae strain XA(T) plasmid unnamed1, complete sequence	110373-110404	8	0.75
NC_015387_6	6.96\|962103\|32\|NC_015387\|CRISPRCasFinder,CRT	962103-962134	32	CP054922	Streptomyces sp. NA03103 plasmid unnamed2, complete sequence	104528-104559	8	0.75
NC_015387_6	6.98\|962225\|33\|NC_015387\|CRISPRCasFinder,CRT	962225-962257	33	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	183504-183536	8	0.758
NC_015387_6	6.98\|962225\|33\|NC_015387\|CRISPRCasFinder,CRT	962225-962257	33	NZ_CP033583	Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence	129175-129207	8	0.758
NC_015387_6	6.98\|962225\|33\|NC_015387\|CRISPRCasFinder,CRT	962225-962257	33	NZ_CP010991	Pseudonocardia sp. EC080625-04 plasmid pFRP1-2, complete sequence	22806-22838	8	0.758
NC_015387_6	6.98\|962225\|33\|NC_015387\|CRISPRCasFinder,CRT	962225-962257	33	NZ_CP011667	Streptomyces sp. Mg1 plasmid pSMg1-3, complete sequence	113172-113204	8	0.758
NC_015387_6	6.105\|962653\|32\|NC_015387\|CRISPRCasFinder,CRT	962653-962684	32	KX758539	Mycobacterium phage Jaan, complete genome	3904-3935	8	0.75
NC_015387_6	6.105\|962653\|32\|NC_015387\|CRISPRCasFinder,CRT	962653-962684	32	MN703408	Mycobacterium phage Phaded, complete genome	3903-3934	8	0.75
NC_015387_6	6.105\|962653\|32\|NC_015387\|CRISPRCasFinder,CRT	962653-962684	32	NC_031279	Mycobacterium phage Bactobuster, complete genome	3900-3931	8	0.75
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	253466-253497	8	0.75
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	318558-318589	8	0.75
NC_015387_10	10.15\|2084521\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	2084521-2084555	35	NZ_CP053565	Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence	24421-24455	8	0.771
NC_015387_10	10.15\|2084521\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	2084521-2084555	35	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	27510-27544	8	0.771
NC_015387_2	2.16\|275168\|34\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	275168-275201	34	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	1004227-1004260	9	0.735
NC_015387_2	2.16\|275168\|34\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	275168-275201	34	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	823054-823087	9	0.735
NC_015387_2	2.21\|275532\|34\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	275532-275565	34	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	518680-518713	9	0.735
NC_015387_2	2.31\|276261\|37\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	276261-276297	37	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	220407-220443	9	0.757
NC_015387_2	2.42\|277063\|36\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	277063-277098	36	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	245675-245710	9	0.75
NC_015387_2	2.44\|277210\|36\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	277210-277245	36	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	245675-245710	9	0.75
NC_015387_6	6.2\|959783\|33\|NC_015387\|PILER-CR	959783-959815	33	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	62203-62235	9	0.727
NC_015387_6	6.6\|960027\|33\|NC_015387\|PILER-CR	960027-960059	33	CP041517	Bacillus aryabhattai strain KNU10 plasmid unnamed1, complete sequence	63912-63944	9	0.727
NC_015387_6	6.7\|960088\|34\|NC_015387\|PILER-CR	960088-960121	34	NZ_CP014675	Kozakia baliensis strain DSM 14400 plasmid pKB14400_1, complete sequence	192314-192347	9	0.735
NC_015387_6	6.8\|960150\|33\|NC_015387\|PILER-CR	960150-960182	33	NZ_CP029358	Azospirillum sp. CFH 70021 plasmid unnamed3	254765-254797	9	0.727
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	NZ_CP007516	Rubrobacter radiotolerans strain RSPS-4 plasmid 2, complete sequence	34157-34189	9	0.727
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	1624773-1624805	9	0.727
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	27225-27257	9	0.727
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1482396-1482428	9	0.727
NC_015387_6	6.20\|960881\|33\|NC_015387\|PILER-CR	960881-960913	33	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	918553-918585	9	0.727
NC_015387_6	6.22\|961003\|34\|NC_015387\|PILER-CR	961003-961036	34	MK937595	Streptomyces phage Dubu, complete genome	34300-34333	9	0.735
NC_015387_6	6.22\|961003\|34\|NC_015387\|PILER-CR	961003-961036	34	MG945161	UNVERIFIED: Microviridae sp. isolate 405-1507, complete genome	3381-3414	9	0.735
NC_015387_6	6.23\|961065\|33\|NC_015387\|PILER-CR	961065-961097	33	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	1005325-1005357	9	0.727
NC_015387_6	6.23\|961065\|33\|NC_015387\|PILER-CR	961065-961097	33	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	1453796-1453828	9	0.727
NC_015387_6	6.31\|961553\|33\|NC_015387\|PILER-CR	961553-961585	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	66934-66966	9	0.727
NC_015387_6	6.31\|961553\|33\|NC_015387\|PILER-CR	961553-961585	33	NZ_CP031163	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdI, complete sequence	97516-97548	9	0.727
NC_015387_6	6.42\|962224\|34\|NC_015387\|PILER-CR	962224-962257	34	NZ_CP010991	Pseudonocardia sp. EC080625-04 plasmid pFRP1-2, complete sequence	22805-22838	9	0.735
NC_015387_6	6.42\|962224\|34\|NC_015387\|PILER-CR	962224-962257	34	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	183504-183537	9	0.735
NC_015387_6	6.42\|962224\|34\|NC_015387\|PILER-CR	962224-962257	34	NZ_CP011667	Streptomyces sp. Mg1 plasmid pSMg1-3, complete sequence	113171-113204	9	0.735
NC_015387_6	6.42\|962224\|34\|NC_015387\|PILER-CR	962224-962257	34	NZ_CP033583	Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence	129175-129208	9	0.735
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	318557-318589	9	0.727
NC_015387_6	6.58\|959784\|32\|NC_015387\|CRISPRCasFinder,CRT	959784-959815	32	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	331941-331972	9	0.719
NC_015387_6	6.58\|959784\|32\|NC_015387\|CRISPRCasFinder,CRT	959784-959815	32	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	561050-561081	9	0.719
NC_015387_6	6.58\|959784\|32\|NC_015387\|CRISPRCasFinder,CRT	959784-959815	32	NC_014723	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH02, complete sequence	161477-161508	9	0.719
NC_015387_6	6.58\|959784\|32\|NC_015387\|CRISPRCasFinder,CRT	959784-959815	32	NC_015065	Granulicella tundricola MP5ACTX9 plasmid pACIX902, complete sequence	295368-295399	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	CAJDKA010000002	Enterococcus phage 163 genome assembly, contig: phage163-genome, whole genome shotgun sequence	89424-89455	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	MT856905	Enterococcus phage vB_EfaM_A2, complete genome	140198-140229	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	MW004544	Enterococcus phage EFGrKN, complete genome	139410-139441	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	MN241318	Enterococcus phage PEf771, complete genome	132460-132491	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	NC_029009	Enterococcus phage EFDG1, complete genome	139518-139549	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	MT909815	Enterococcus phage iF6, complete genome	139065-139096	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	KY549443	Enterococcus phage EFP01, complete genome	7210-7241	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	MH880817	Enterococcus phage EfV12-phi1, complete genome	143154-143185	9	0.719
NC_015387_6	6.59\|959845\|32\|NC_015387\|CRISPRCasFinder,CRT	959845-959876	32	MN027503	Enterococcus phage vB_OCPT_Ben, complete genome	11157-11188	9	0.719
NC_015387_6	6.63\|960089\|33\|NC_015387\|CRISPRCasFinder,CRT	960089-960121	33	NZ_CP014675	Kozakia baliensis strain DSM 14400 plasmid pKB14400_1, complete sequence	192314-192346	9	0.727
NC_015387_6	6.64\|960151\|32\|NC_015387\|CRISPRCasFinder,CRT	960151-960182	32	NZ_CP024427	Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence	112383-112414	9	0.719
NC_015387_6	6.64\|960151\|32\|NC_015387\|CRISPRCasFinder,CRT	960151-960182	32	NZ_CP020443	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence	122059-122090	9	0.719
NC_015387_6	6.64\|960151\|32\|NC_015387\|CRISPRCasFinder,CRT	960151-960182	32	NZ_CP029358	Azospirillum sp. CFH 70021 plasmid unnamed3	254765-254796	9	0.719
NC_015387_6	6.64\|960151\|32\|NC_015387\|CRISPRCasFinder,CRT	960151-960182	32	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	182921-182952	9	0.719
NC_015387_6	6.64\|960151\|32\|NC_015387\|CRISPRCasFinder,CRT	960151-960182	32	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1056221-1056252	9	0.719
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP007516	Rubrobacter radiotolerans strain RSPS-4 plasmid 2, complete sequence	34157-34188	9	0.719
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	27226-27257	9	0.719
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_LR134452	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence	356589-356620	9	0.719
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	176132-176163	9	0.719
NC_015387_6	6.68\|960395\|32\|NC_015387\|CRISPRCasFinder,CRT	960395-960426	32	NZ_CP032928	Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence	160891-160922	9	0.719
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	MG198779	Arthrobacter phage Urla, complete genome	37291-37322	9	0.719
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	736457-736488	9	0.719
NC_015387_6	6.84\|961371\|32\|NC_015387\|CRISPRCasFinder,CRT	961371-961402	32	NZ_CP021126	Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence	390144-390175	9	0.719
NC_015387_6	6.87\|961554\|32\|NC_015387\|CRISPRCasFinder,CRT	961554-961585	32	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	315146-315177	9	0.719
NC_015387_6	6.87\|961554\|32\|NC_015387\|CRISPRCasFinder,CRT	961554-961585	32	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	66934-66965	9	0.719
NC_015387_6	6.87\|961554\|32\|NC_015387\|CRISPRCasFinder,CRT	961554-961585	32	NZ_CP031163	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdI, complete sequence	97517-97548	9	0.719
NC_015387_6	6.87\|961554\|32\|NC_015387\|CRISPRCasFinder,CRT	961554-961585	32	NZ_CP020445	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence	111470-111501	9	0.719
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NC_015057	Granulicella tundricola MP5ACTX9 plasmid pACIX901, complete sequence	319626-319657	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MN175603	Microbacterium phage Tyrumbra, complete genome	9228-9259	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MN586042	Microbacterium phage Jayden, complete genome	9808-9839	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MN813684	Microbacterium phage Terij, complete genome	7873-7904	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MH155873	Microbacterium phage Paschalis, complete genome	10251-10282	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MH590600	Microbacterium phage KaiHaiDragon, complete genome	10146-10177	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MH271312	Microbacterium phage RobsFeet, complete genome	10152-10183	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MT818415	Microbacterium phage Scumberland, complete genome	10476-10507	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	NC_047993	Microbacterium phage Quhwah, complete genome	10606-10637	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MN062719	Microbacterium phage PiperSansNom, complete genome	10555-10586	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MN444877	Microbacterium phage Antares, complete genome	10470-10501	9	0.719
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	NC_047988	Microbacterium phage Metamorphoo, complete genome	9871-9902	9	0.719
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1093232-1093263	9	0.719
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1092373-1092404	9	0.719
NC_015387_2	2.5\|274374\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274374-274408	35	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	4280-4314	10	0.714
NC_015387_2	2.12\|274877\|35\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	274877-274911	35	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	736457-736491	10	0.714
NC_015387_2	2.31\|276261\|37\|NC_015387\|PILER-CR,CRISPRCasFinder,CRT	276261-276297	37	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	90291-90327	10	0.73
NC_015387_6	6.8\|960150\|33\|NC_015387\|PILER-CR	960150-960182	33	NZ_CP024427	Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence	112382-112414	10	0.697
NC_015387_6	6.8\|960150\|33\|NC_015387\|PILER-CR	960150-960182	33	NZ_CP020443	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence	122058-122090	10	0.697
NC_015387_6	6.8\|960150\|33\|NC_015387\|PILER-CR	960150-960182	33	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	182921-182953	10	0.697
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	NZ_LR594660	Variovorax sp. PBL-H6 plasmid 2	796583-796615	10	0.697
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	NZ_LR594667	Variovorax sp. SRS16 plasmid 2	41574-41606	10	0.697
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	NZ_LR594690	Variovorax sp. WDL1 plasmid 2	41574-41606	10	0.697
NC_015387_6	6.9\|960211\|33\|NC_015387\|PILER-CR	960211-960243	33	NZ_LR594672	Variovorax sp. PBL-E5 plasmid 2	41574-41606	10	0.697
NC_015387_6	6.12\|960394\|33\|NC_015387\|PILER-CR	960394-960426	33	NZ_CP032928	Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence	160891-160923	10	0.697
NC_015387_6	6.23\|961065\|33\|NC_015387\|PILER-CR	961065-961097	33	MG198779	Arthrobacter phage Urla, complete genome	37290-37322	10	0.697
NC_015387_6	6.28\|961370\|33\|NC_015387\|PILER-CR	961370-961402	33	NZ_CP021126	Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence	390143-390175	10	0.697
NC_015387_6	6.31\|961553\|33\|NC_015387\|PILER-CR	961553-961585	33	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	315146-315178	10	0.697
NC_015387_6	6.54\|962957\|33\|NC_015387\|PILER-CR	962957-962989	33	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1093231-1093263	10	0.697
NC_015387_6	6.60\|959906\|32\|NC_015387\|CRISPRCasFinder,CRT	959906-959937	32	NZ_CP016476	Synechococcus sp. PCC 7003 plasmid unnamed2, complete sequence	125473-125504	10	0.688
NC_015387_6	6.62\|960028\|32\|NC_015387\|CRISPRCasFinder,CRT	960028-960059	32	KF929199	Staphylococcus phage vB_SepS_SEP9, complete genome	90193-90224	10	0.688
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_LR594660	Variovorax sp. PBL-H6 plasmid 2	796583-796614	10	0.688
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_LR594667	Variovorax sp. SRS16 plasmid 2	41575-41606	10	0.688
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_LR594690	Variovorax sp. WDL1 plasmid 2	41575-41606	10	0.688
NC_015387_6	6.65\|960212\|32\|NC_015387\|CRISPRCasFinder,CRT	960212-960243	32	NZ_LR594672	Variovorax sp. PBL-E5 plasmid 2	41575-41606	10	0.688
NC_015387_6	6.76\|960882\|32\|NC_015387\|CRISPRCasFinder,CRT	960882-960913	32	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	410047-410078	10	0.688
NC_015387_6	6.76\|960882\|32\|NC_015387\|CRISPRCasFinder,CRT	960882-960913	32	NC_016567	Vibrio phage SIO-2, complete genome	42685-42716	10	0.688
NC_015387_6	6.78\|961004\|33\|NC_015387\|CRISPRCasFinder,CRT	961004-961036	33	DQ163916	Bacteriophage M6, complete genome	4459-4491	10	0.697
NC_015387_6	6.78\|961004\|33\|NC_015387\|CRISPRCasFinder,CRT	961004-961036	33	NC_007809	Pseudomonas phage M6, complete genome	4459-4491	10	0.697
NC_015387_6	6.78\|961004\|33\|NC_015387\|CRISPRCasFinder,CRT	961004-961036	33	MN183284	Microbacterium phage Mashley, complete genome	5121-5153	10	0.697
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP024582	Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence	231696-231727	10	0.688
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_LT984809	Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence	254946-254977	10	0.688
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NC_008545	Burkholderia cenocepacia HI2424 plasmid unnamed1, complete sequence	10172-10203	10	0.688
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	NZ_CP025188	Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence	173148-173179	10	0.688
NC_015387_6	6.79\|961066\|32\|NC_015387\|CRISPRCasFinder,CRT	961066-961097	32	EF523948	Burkholderia phage BcepGomr, complete genome	8841-8872	10	0.688
NC_015387_6	6.85\|961432\|32\|NC_015387\|CRISPRCasFinder,CRT	961432-961463	32	NZ_CP020926	Sphingobium yanoikuyae strain SHJ plasmid pSES220, complete sequence	117283-117314	10	0.688
NC_015387_6	6.85\|961432\|32\|NC_015387\|CRISPRCasFinder,CRT	961432-961463	32	NZ_AP018666	Sphingobium amiense strain DSM 16289 plasmid pSAMIE_3, complete sequence	920-951	10	0.688
NC_015387_6	6.85\|961432\|32\|NC_015387\|CRISPRCasFinder,CRT	961432-961463	32	NZ_CP053023	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-B-Sy, complete sequence	26614-26645	10	0.688
NC_015387_6	6.85\|961432\|32\|NC_015387\|CRISPRCasFinder,CRT	961432-961463	32	NZ_CP022747	Sphingobium hydrophobicum strain C1 plasmid p1, complete sequence	227878-227909	10	0.688
NC_015387_6	6.86\|961493\|32\|NC_015387\|CRISPRCasFinder,CRT	961493-961524	32	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	40570-40601	10	0.688
NC_015387_6	6.95\|962042\|32\|NC_015387\|CRISPRCasFinder,CRT	962042-962073	32	NZ_CP013558	Rhizobium phaseoli strain N841 plasmid pRphaN841a, complete sequence	34892-34923	10	0.688
NC_015387_6	6.96\|962103\|32\|NC_015387\|CRISPRCasFinder,CRT	962103-962134	32	NC_019387	Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence	95930-95961	10	0.688
NC_015387_6	6.97\|962164\|32\|NC_015387\|CRISPRCasFinder,CRT	962164-962195	32	NC_019387	Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence	145470-145501	10	0.688
NC_015387_6	6.100\|962348\|32\|NC_015387\|CRISPRCasFinder,CRT	962348-962379	32	NZ_JX627580	Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence	95783-95814	10	0.688
NC_015387_6	6.103\|962531\|32\|NC_015387\|CRISPRCasFinder,CRT	962531-962562	32	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	975808-975839	10	0.688
NC_015387_6	6.106\|962714\|32\|NC_015387\|CRISPRCasFinder,CRT	962714-962745	32	NZ_CP023367	Escherichia coli strain 1428 plasmid p111, complete sequence	12762-12793	10	0.688
NC_015387_6	6.107\|962775\|32\|NC_015387\|CRISPRCasFinder,CRT	962775-962806	32	MK937606	Microbacterium phage Margaery, complete genome	7805-7836	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NC_022539	Xanthomonas citri pv. fuscans plasmid pla, complete sequence	3356-3387	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020984	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6990 plasmid pA, complete sequence	33100-33131	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020986	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6992 plasmid pA, complete sequence	29611-29642	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NC_013958	Nitrosococcus halophilus Nc 4 plasmid pNHAL01, complete sequence	14060-14091	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP021008	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6975 plasmid pA, complete sequence	34708-34739	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020993	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pA, complete sequence	2726-2757	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020993	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pA, complete sequence	47031-47062	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3216691-3216722	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP021019	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167 plasmid pA, complete sequence	21017-21048	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP021017	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6991 plasmid pA, complete sequence	49316-49347	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020982	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6989 plasmid pA, complete sequence	1176-1207	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020982	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6989 plasmid pA, complete sequence	58246-58277	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020990	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6996R plasmid pA, complete sequence	17553-17584	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020999	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6165 plasmid pA, complete sequence	24767-24798	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP021002	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pA, complete sequence	35101-35132	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	CP021013	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP7767 plasmid pA, complete sequence	17711-17742	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020980	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6988R plasmid pA, complete sequence	47225-47256	10	0.688
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP020988	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6994R plasmid pA, complete sequence	42307-42338	10	0.688
NC_015387_7	7.7\|1466414\|38\|NC_015387\|CRISPRCasFinder	1466414-1466451	38	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	729948-729985	10	0.737
NC_015387_7	7.7\|1466414\|38\|NC_015387\|CRISPRCasFinder	1466414-1466451	38	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1009597-1009634	10	0.737
NC_015387_7	7.61\|1466415\|38\|NC_015387\|CRT	1466415-1466452	38	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1009598-1009635	10	0.737
NC_015387_6	6.22\|961003\|34\|NC_015387\|PILER-CR	961003-961036	34	DQ163916	Bacteriophage M6, complete genome	4459-4492	11	0.676
NC_015387_6	6.22\|961003\|34\|NC_015387\|PILER-CR	961003-961036	34	NC_007809	Pseudomonas phage M6, complete genome	4459-4492	11	0.676
NC_015387_6	6.22\|961003\|34\|NC_015387\|PILER-CR	961003-961036	34	MN183284	Microbacterium phage Mashley, complete genome	5121-5154	11	0.676
NC_015387_6	6.50\|962713\|33\|NC_015387\|PILER-CR	962713-962745	33	NZ_CP023367	Escherichia coli strain 1428 plasmid p111, complete sequence	12762-12794	11	0.667
NC_015387_6	6.85\|961432\|32\|NC_015387\|CRISPRCasFinder,CRT	961432-961463	32	NC_009507	Sphingomonas wittichii RW1 plasmid pSWIT01, complete sequence	152217-152248	11	0.656
NC_015387_6	6.93\|961920\|32\|NC_015387\|CRISPRCasFinder,CRT	961920-961951	32	MN095770	Serratia phage Slocum, complete genome	83135-83166	11	0.656
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP044082	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence	267671-267702	11	0.656
NC_015387_6	6.110\|962958\|32\|NC_015387\|CRISPRCasFinder,CRT	962958-962989	32	NZ_CP031080	Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence	159296-159327	11	0.656

1. spacer 6.23|961065|33|NC_015387|PILER-CR matches to MH825706 (Streptomyces phage Microdon, complete genome) position: , mismatch: 4, identity: 0.879

gaacgagcaccgcgccgcgatcatcctgaacgc-	CRISPR spacer
gagcgagcaccgcgccgcgatcatcc-gggcgct	Protospacer
**.*********************** *..***

2. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MH825706 (Streptomyces phage Microdon, complete genome) position: , mismatch: 4, identity: 0.875

aacgagcaccgcgccgcgatcatcctgaacgc-	CRISPR spacer
agcgagcaccgcgccgcgatcatcc-gggcgct	Protospacer
*.*********************** *..***

3. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN871446 (UNVERIFIED: Serratia phage KpLz-2_45, complete genome) position: , mismatch: 5, identity: 0.844

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aaacagcacagcgccgcgatcagcctgaacgg	Protospacer
**  ***** ************ ********

4. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN871452 (UNVERIFIED: Serratia phage KpZh_1, complete genome) position: , mismatch: 5, identity: 0.844

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aaacagcacagcgccgcgatcagcctgaacgg	Protospacer
**  ***** ************ ********

5. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN871447 (UNVERIFIED: Serratia phage KpLz_1_41, complete genome) position: , mismatch: 5, identity: 0.844

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aaacagcacagcgccgcgatcagcctgaacgg	Protospacer
**  ***** ************ ********

6. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN871449 (UNVERIFIED: Serratia phage KpXa_1, complete genome) position: , mismatch: 5, identity: 0.844

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aaacagcacagcgccgcgatcagcctgaacgg	Protospacer
**  ***** ************ ********

7. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN871453 (UNVERIFIED: Serratia phage KpZh_LPS_45, complete genome) position: , mismatch: 5, identity: 0.844

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aaacagcacagcgccgcgatcagcctgaacgg	Protospacer
**  ***** ************ ********

8. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN871451 (UNVERIFIED: Serratia phage KpYy_2_45, complete genome) position: , mismatch: 5, identity: 0.844

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aaacagcacagcgccgcgatcagcctgaacgg	Protospacer
**  ***** ************ ********

9. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN871448 (UNVERIFIED: Serratia phage KpSz_1, complete genome) position: , mismatch: 5, identity: 0.844

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aaacagcacagcgccgcgatcagcctgaacgg	Protospacer
**  ***** ************ ********

10. spacer 6.11|960333|33|NC_015387|PILER-CR matches to NZ_LR134461 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence) position: , mismatch: 6, identity: 0.818

gtccacggtctcctccaggaccgcgccccggtc---	CRISPR spacer
gtccacgttctgctccaggaccg---cctggtccgc	Protospacer
******* *** ***********   **.****

11. spacer 6.29|961431|33|NC_015387|PILER-CR matches to AP014720 (Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8) position: , mismatch: 6, identity: 0.818

gtttagtctcgagctcgctgctccgcgcctcag	CRISPR spacer
gctgcgtgtcgagctcgcttctccgcgcctcaa	Protospacer
*.*  ** *********** ************.

12. spacer 6.67|960334|32|NC_015387|CRISPRCasFinder,CRT matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 6, identity: 0.812

tccacggtctcctccaggaccgcgccccggtc	CRISPR spacer
tggaccgtctcctccaggacctcgccccgccc	Protospacer
*  ** *************** ******* .*

13. spacer 6.67|960334|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR134461 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 19, complete sequence) position: , mismatch: 6, identity: 0.812

tccacggtctcctccaggaccgcgccccggtc---	CRISPR spacer
tccacgttctgctccaggaccg---cctggtccgc	Protospacer
****** *** ***********   **.****

14. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to NC_017533 (Pantoea ananatis AJ13355 plasmid pEA320, complete sequence) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

15. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to NC_016817 (Pantoea ananatis LMG 5342 plasmid pPANA10, complete sequence) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

16. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020944 (Pantoea ananatis strain PNA 97-1R plasmid unamed1, complete sequence) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

17. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP014208 (Pantoea ananatis strain R100 plasmid, complete sequence) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

18. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to NC_017553 (Pantoea ananatis PA13 plasmid PAGR_p, complete sequence) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

19. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to CP054909 (Pantoea ananatis strain FDAARGOS_680 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

20. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP022429 (Pantoea ananatis strain YJ76 plasmid p_unamed1) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

21. spacer 6.72|960638|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP035036 (Pantoea ananatis strain NN08200 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

---gagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
caccaggg---acgcggggcggaaaacctgctctc	Protospacer
    ****   *****.**** *************

22. spacer 6.85|961432|32|NC_015387|CRISPRCasFinder,CRT matches to AP014720 (Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8) position: , mismatch: 6, identity: 0.812

tttagtctcgagctcgctgctccgcgcctcag	CRISPR spacer
ctgcgtgtcgagctcgcttctccgcgcctcaa	Protospacer
.*  ** *********** ************.

23. spacer 6.98|962225|33|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.818

aacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
atcgggttgagcaccacggcgaacgcgtccggc	Protospacer
* **  ************ ************

24. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013597 (Rhizobium sp. N741 plasmid pRspN741b, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

25. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013501 (Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

26. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013507 (Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

27. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013518 (Rhizobium sp. N113 plasmid pRspN113a, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

28. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013491 (Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

29. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013513 (Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

30. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013496 (Rhizobium sp. N621 plasmid pRspN621a, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

31. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013591 (Rhizobium sp. N871 plasmid pRspN871a, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

32. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013603 (Rhizobium sp. N731 plasmid pRspN731b, complete sequence) position: , mismatch: 6, identity: 0.812

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgcgtgac	Protospacer
..******************  ****** *.*

33. spacer 2.2|274157|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.8

acgaggccgcgagccgcctccgcatgcagctcgag	CRISPR spacer
acgaggcggcgagccgcctgcgcatggccatcgac	Protospacer
******* *********** ******    ****

34. spacer 2.2|274157|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.8

acgaggccgcgagccgcctccgcatgcagctcgag	CRISPR spacer
acgaggcggcgagccgcctgcgcatggccatcgac	Protospacer
******* *********** ******    ****

35. spacer 2.2|274157|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 7, identity: 0.8

acgaggccgcgagccgcctccgcatgcagctcgag	CRISPR spacer
acgaggcggcgagccgcctgcgcatggccatcgac	Protospacer
******* *********** ******    ****

36. spacer 2.2|274157|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 7, identity: 0.8

acgaggccgcgagccgcctccgcatgcagctcgag	CRISPR spacer
acgaggcggcgagccgcctgcgcatggccatcgac	Protospacer
******* *********** ******    ****

37. spacer 6.11|960333|33|NC_015387|PILER-CR matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 7, identity: 0.788

gtccacggtctcctccaggaccgcgccccggtc	CRISPR spacer
ctggaccgtctcctccaggacctcgccccgccc	Protospacer
 *  ** *************** ******* .*

38. spacer 6.22|961003|34|NC_015387|PILER-CR matches to MK291445 (Paracoccus phage vB_PyeM_Pyei1, complete genome) position: , mismatch: 7, identity: 0.794

aggacctcctcgcccgtctccgcgtccacggttc--	CRISPR spacer
atgaccgcctcgcccgtctccgggtcgat--ttcgg	Protospacer
* **** *************** *** *.  ***

39. spacer 6.42|962224|34|NC_015387|PILER-CR matches to NZ_CP045548 (Streptomyces sp. SYP-A7193 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

gaacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
catcgggttgagcaccacggcgaacgcgtccggc	Protospacer
 * **  ************ ************

40. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013597 (Rhizobium sp. N741 plasmid pRspN741b, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

41. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013501 (Rhizobium esperanzae strain N561 plasmid pRspN561a, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

42. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013507 (Rhizobium sp. N1341 plasmid pRspN1341b, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

43. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013518 (Rhizobium sp. N113 plasmid pRspN113a, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

44. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013491 (Rhizobium sp. N6212 plasmid pRspN6212a, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

45. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013513 (Rhizobium sp. N1314 plasmid pRspN1314b, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

46. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013496 (Rhizobium sp. N621 plasmid pRspN621a, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

47. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013591 (Rhizobium sp. N871 plasmid pRspN871a, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

48. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP013603 (Rhizobium sp. N731 plasmid pRspN731b, complete sequence) position: , mismatch: 7, identity: 0.788

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgcgtgac	Protospacer
...******************  ****** *.*

49. spacer 6.58|959784|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP033971 (Cupriavidus pauculus strain FDAARGOS_614 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

cctgggccgcaccgatccaggccgcccaagcg	CRISPR spacer
cctccacgtcaacgatccaggccgcccaggcg	Protospacer
***  .*  ** ****************.***

50. spacer 6.60|959906|32|NC_015387|CRISPRCasFinder,CRT matches to NC_018685 (Bacillus thuringiensis MC28 plasmid pMC95, complete sequence) position: , mismatch: 7, identity: 0.781

tacctggacccaccccaaacacccgaaacgaa	CRISPR spacer
tatgttcatccaccccaaacacccgatacaaa	Protospacer
**. *  *.***************** **.**

51. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 7, identity: 0.781

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
cgctgctcggcctgccggacctcctcctccac	Protospacer
* *.*****. ******************  .

52. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP032314 (Pannonibacter phragmitetus BB plasmid p.BB_2, complete sequence) position: , mismatch: 7, identity: 0.781

ccccgctcgagctgccggacctcctcctcact-	CRISPR spacer
tctcgcttgagctgccggatctcct-cagactg	Protospacer
.*.****.***********.***** *  ***

53. spacer 6.78|961004|33|NC_015387|CRISPRCasFinder,CRT matches to MK291445 (Paracoccus phage vB_PyeM_Pyei1, complete genome) position: , mismatch: 7, identity: 0.788

ggacctcctcgcccgtctccgcgtccacggttc--	CRISPR spacer
tgaccgcctcgcccgtctccgggtcgat--ttcgg	Protospacer
 **** *************** *** *.  ***

54. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 7, identity: 0.781

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gacgaccaccgcgccgcgatcatcaccaagac	Protospacer
.**** ****************** . ** .*

55. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 7, identity: 0.781

aacgagc--accgcgccgcgatcatcctgaacgc	CRISPR spacer
--ccggctgcccgcgcggcgatcatcctgaaggc	Protospacer
  * .**   ****** ************** **

56. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 7, identity: 0.781

aacgagc--accgcgccgcgatcatcctgaacgc	CRISPR spacer
--ccggctgcccgcgcggcgatcatcctgaaggc	Protospacer
  * .**   ****** ************** **

57. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MH229864 (Streptomyces phage UNTPL, complete genome) position: , mismatch: 7, identity: 0.781

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
agcgtgcaccgggccgcgatcatccgggccga	Protospacer
*.** ****** ************* *. **

58. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP010590 (Phaeobacter gallaeciensis strain P11 plasmid pP11_b, complete sequence) position: , mismatch: 7, identity: 0.781

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
tcgaaggggtcaaagccgatggcccgggcgag	Protospacer
** . **.****.**************** *

59. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP010675 (Phaeobacter gallaeciensis strain P75 plasmid pP75_b, complete sequence) position: , mismatch: 7, identity: 0.781

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
tcgaaggggtcaaagccgatggcccgggcgag	Protospacer
** . **.****.**************** *

60. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NC_023148 (Phaeobacter gallaeciensis DSM 26640 plasmid pGal_B134, complete sequence) position: , mismatch: 7, identity: 0.781

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
tcgaaggggtcaaagccgatggcccgggcgag	Protospacer
** . **.****.**************** *

61. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP010791 (Phaeobacter gallaeciensis strain P63 plasmid pP63_x_draft, complete sequence) position: , mismatch: 7, identity: 0.781

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
tcgaaggggtcaaagccgatggcccgggcgag	Protospacer
** . **.****.**************** *

62. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP010631 (Phaeobacter inhibens strain P78 plasmid pP78_b, complete sequence) position: , mismatch: 7, identity: 0.781

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
tcgaaggggtcaaagccgatggcccgggcgag	Protospacer
** . **.****.**************** *

63. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP010619 (Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_b, complete sequence) position: , mismatch: 7, identity: 0.781

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
tcgaaggggtcaaagccgatggcccgggcgag	Protospacer
** . **.****.**************** *

64. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP010638 (Phaeobacter gallaeciensis strain P73 plasmid pP73_b, complete sequence) position: , mismatch: 7, identity: 0.781

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
tcgaaggggtcaaagccgatggcccgggcgag	Protospacer
** . **.****.**************** *

65. spacer 6.98|962225|33|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP032350 (Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence) position: , mismatch: 7, identity: 0.788

aacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
atctcgttgagcaccgcgccgaacgcgcccggc	Protospacer
* * * *********.***********.***

66. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cctgccacgccgcgcaccatcagccgcgtgac	Protospacer
...*****************  ****** *.*

67. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NC_007764 (Rhizobium etli CFN 42 plasmid p42c, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgggtgac	Protospacer
..******************  **** * *.*

68. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020908 (Rhizobium etli strain NXC12 plasmid pRetNXC12b, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgggtgac	Protospacer
..******************  **** * *.*

69. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NC_021907 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1b, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
cccgccacgccgcgcaccatcagccgggtgac	Protospacer
..******************  **** * *.*

70. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR134466 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 24, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
ttcttgatgccgcgcaccatgcgcagcgtgga	Protospacer
*** . *.**************** *** **

71. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP006987 (Rhizobium sp. IE4771 plasmid pRetIE4771a, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgccgcggggc-	CRISPR spacer
ctcgcgacgccgcgcatcatgcg-cgcgagctc	Protospacer
.**** **********.****** ****.* .

72. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
atcgcgacgccgcgcacgatgcgcggtgccgc	Protospacer
 **** *********** ****** *.*  **

73. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 7, identity: 0.781

ttcgccacgccgcgcaccatgcgc-cgcggggc	CRISPR spacer
gtcgccaagccgcgcaccaggcgcatgccgag-	Protospacer
 ****** *********** **** .** *.*

74. spacer 7.9|1466552|37|NC_015387|CRISPRCasFinder matches to NZ_CP019063 (Rahnella sp. ERMR1:05 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.811

ccgggcgcggcgtgaggcggatatgtgggccagggag---	CRISPR spacer
ccggttgcggcgtgaggcggatatgt---tcagggcggat	Protospacer
**** .********************   .***** *

75. spacer 7.51|1467555|37|NC_015387|PILER-CR matches to NZ_CP043619 (Rhodobacteraceae bacterium SH-1 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.811

--ctgcagaagacctgatggagcggctcggccgcctgaa	CRISPR spacer
acctgccgctg--ctgatggagccgcgcggccgcctgaa	Protospacer
  **** *  *  ********** ** ************

76. spacer 7.78|1467556|36|NC_015387|CRT matches to NZ_CP043619 (Rhodobacteraceae bacterium SH-1 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.806

--tgcagaagacctgatggagcggctcggccgcctgaa	CRISPR spacer
cctgccgctg--ctgatggagccgcgcggccgcctgaa	Protospacer
  *** *  *  ********** ** ************

77. spacer 2.2|274157|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.771

acgaggccgcgagccgcctccgcatgcagctcgag	CRISPR spacer
acgaggcggcgagccgcctgcgcatggccgtggac	Protospacer
******* *********** ******    * **

78. spacer 2.2|274157|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 8, identity: 0.771

acgaggccgcgagccgcctccgcatgcagctcgag	CRISPR spacer
acgaggcggcgagccgcctgcgcatggccgtggac	Protospacer
******* *********** ******    * **

79. spacer 6.8|960150|33|NC_015387|PILER-CR matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 8, identity: 0.758

ggcgcggctcgagcccgtccagca-cgcaaaacc	CRISPR spacer
ggcgcggctccagcccgtccatcagcgtgagga-	Protospacer
********** ********** ** **..*..

80. spacer 6.11|960333|33|NC_015387|PILER-CR matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 8, identity: 0.758

gtccacggtctcctccaggaccgcgccccggtc	CRISPR spacer
ggccacggtctcctccacgagcgcgcgcggcga	Protospacer
* *************** ** ***** * *

81. spacer 6.16|960637|33|NC_015387|PILER-CR matches to NC_016817 (Pantoea ananatis LMG 5342 plasmid pPANA10, complete sequence) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

82. spacer 6.16|960637|33|NC_015387|PILER-CR matches to NZ_CP020944 (Pantoea ananatis strain PNA 97-1R plasmid unamed1, complete sequence) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

83. spacer 6.16|960637|33|NC_015387|PILER-CR matches to NC_017553 (Pantoea ananatis PA13 plasmid PAGR_p, complete sequence) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

84. spacer 6.16|960637|33|NC_015387|PILER-CR matches to NZ_CP022429 (Pantoea ananatis strain YJ76 plasmid p_unamed1) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

85. spacer 6.16|960637|33|NC_015387|PILER-CR matches to NC_017533 (Pantoea ananatis AJ13355 plasmid pEA320, complete sequence) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

86. spacer 6.16|960637|33|NC_015387|PILER-CR matches to NZ_CP014208 (Pantoea ananatis strain R100 plasmid, complete sequence) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

87. spacer 6.16|960637|33|NC_015387|PILER-CR matches to CP054909 (Pantoea ananatis strain FDAARGOS_680 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

88. spacer 6.16|960637|33|NC_015387|PILER-CR matches to NZ_CP035036 (Pantoea ananatis strain NN08200 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

-----agagggactacgcgaggcgcaaaacctgctctc	CRISPR spacer
ccaccaggg-----acgcggggcggaaaacctgctctc	Protospacer
     **.*     *****.**** *************

89. spacer 6.20|960881|33|NC_015387|PILER-CR matches to NZ_CP016453 (Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence) position: , mismatch: 8, identity: 0.758

ctctagcccctgcaacacaaagccccgccccca	CRISPR spacer
ctcatacccctgcaacgcaaagccgcgcccatc	Protospacer
***  .**********.******* ***** .

90. spacer 6.23|961065|33|NC_015387|PILER-CR matches to NZ_LR134454 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence) position: , mismatch: 8, identity: 0.758

gaacgagcaccgcgccgcgatcatcctgaacgc---	CRISPR spacer
gaacgagcaccgcgccgagctca---tggacatggt	Protospacer
***************** * ***   **.**..

91. spacer 6.28|961370|33|NC_015387|PILER-CR matches to NZ_CP044989 (Deinococcus sp. AJ005 plasmid p380k, complete sequence) position: , mismatch: 8, identity: 0.758

-----gagggtgccgcttacctacaagagcgtcaaggt	CRISPR spacer
ggtctgag-----cggttacctacaagagcgtcacggc	Protospacer
     ***     ** ****************** **.

92. spacer 6.31|961553|33|NC_015387|PILER-CR matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.758

gctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
ggggccgcgcccttgcctcgccgatccgggcga	Protospacer
*  *  ***** ************* **** *

93. spacer 6.39|962041|33|NC_015387|PILER-CR matches to NZ_CP020716 (Cnuibacter physcomitrellae strain XA(T) plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

aagtgggaggaagccaaagccaccagggccgtt	CRISPR spacer
aacacagaggaagccaaagccaccaccgccgag	Protospacer
**   .*******************  ****

94. spacer 6.40|962102|33|NC_015387|PILER-CR matches to CP054922 (Streptomyces sp. NA03103 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

gccctcctggactggttacggcaggacccgccc	CRISPR spacer
ggcccgctggactggttgcggcaggagccgtgg	Protospacer
* **. ***********.******** ***.

95. spacer 6.41|962163|33|NC_015387|PILER-CR matches to NZ_CP010590 (Phaeobacter gallaeciensis strain P11 plasmid pP11_b, complete sequence) position: , mismatch: 8, identity: 0.758

gtctgcggagtcagagccgatggcccgggccat	CRISPR spacer
atcgaaggggtcaaagccgatggcccgggcgag	Protospacer
.** . **.****.**************** *

96. spacer 6.41|962163|33|NC_015387|PILER-CR matches to NZ_CP010675 (Phaeobacter gallaeciensis strain P75 plasmid pP75_b, complete sequence) position: , mismatch: 8, identity: 0.758

gtctgcggagtcagagccgatggcccgggccat	CRISPR spacer
atcgaaggggtcaaagccgatggcccgggcgag	Protospacer
.** . **.****.**************** *

97. spacer 6.41|962163|33|NC_015387|PILER-CR matches to NC_023148 (Phaeobacter gallaeciensis DSM 26640 plasmid pGal_B134, complete sequence) position: , mismatch: 8, identity: 0.758

gtctgcggagtcagagccgatggcccgggccat	CRISPR spacer
atcgaaggggtcaaagccgatggcccgggcgag	Protospacer
.** . **.****.**************** *

98. spacer 6.41|962163|33|NC_015387|PILER-CR matches to NZ_CP010791 (Phaeobacter gallaeciensis strain P63 plasmid pP63_x_draft, complete sequence) position: , mismatch: 8, identity: 0.758

gtctgcggagtcagagccgatggcccgggccat	CRISPR spacer
atcgaaggggtcaaagccgatggcccgggcgag	Protospacer
.** . **.****.**************** *

99. spacer 6.41|962163|33|NC_015387|PILER-CR matches to NZ_CP010631 (Phaeobacter inhibens strain P78 plasmid pP78_b, complete sequence) position: , mismatch: 8, identity: 0.758

gtctgcggagtcagagccgatggcccgggccat	CRISPR spacer
atcgaaggggtcaaagccgatggcccgggcgag	Protospacer
.** . **.****.**************** *

100. spacer 6.41|962163|33|NC_015387|PILER-CR matches to NZ_CP010619 (Phaeobacter inhibens strain P30 isolate M4-3.1A plasmid pP30_b, complete sequence) position: , mismatch: 8, identity: 0.758

gtctgcggagtcagagccgatggcccgggccat	CRISPR spacer
atcgaaggggtcaaagccgatggcccgggcgag	Protospacer
.** . **.****.**************** *

101. spacer 6.41|962163|33|NC_015387|PILER-CR matches to NZ_CP010638 (Phaeobacter gallaeciensis strain P73 plasmid pP73_b, complete sequence) position: , mismatch: 8, identity: 0.758

gtctgcggagtcagagccgatggcccgggccat	CRISPR spacer
atcgaaggggtcaaagccgatggcccgggcgag	Protospacer
.** . **.****.**************** *

102. spacer 6.42|962224|34|NC_015387|PILER-CR matches to NZ_CP032350 (Azospirillum brasilense strain MTCC4039 plasmid p5, complete sequence) position: , mismatch: 8, identity: 0.765

gaacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
catctcgttgagcaccgcgccgaacgcgcccggc	Protospacer
 * * * *********.***********.***

103. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 8, identity: 0.758

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acctgccacgccgcgcaccatcagccgcgtgac	Protospacer
....*****************  ****** *.*

104. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NC_007764 (Rhizobium etli CFN 42 plasmid p42c, complete sequence) position: , mismatch: 8, identity: 0.758

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgggtgac	Protospacer
...******************  **** * *.*

105. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP020908 (Rhizobium etli strain NXC12 plasmid pRetNXC12b, complete sequence) position: , mismatch: 8, identity: 0.758

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgggtgac	Protospacer
...******************  **** * *.*

106. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NC_021907 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1b, complete sequence) position: , mismatch: 8, identity: 0.758

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
acccgccacgccgcgcaccatcagccgggtgac	Protospacer
...******************  **** * *.*

107. spacer 6.58|959784|32|NC_015387|CRISPRCasFinder,CRT matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

cctgggccgcaccgatccaggccgcccaagcg	CRISPR spacer
tctggcccgcaccgatccaggctgcgaggccg	Protospacer
.**** ****************.**  .. **

108. spacer 6.62|960028|32|NC_015387|CRISPRCasFinder,CRT matches to CP041517 (Bacillus aryabhattai strain KNU10 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ccttcactaaccagaaaaacgaagaaaaaagc	CRISPR spacer
aaaacacttaccagaaaaacgaaggaaattgc	Protospacer
    **** ***************.***  **

109. spacer 6.64|960151|32|NC_015387|CRISPRCasFinder,CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 8, identity: 0.75

gcgcggctcgagcccgtccagca-cgcaaaacc	CRISPR spacer
gcgcggctccagcccgtccatcagcgtgagga-	Protospacer
********* ********** ** **..*..

110. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 8, identity: 0.75

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
ccccgcttgagccgccggacctccttgagcca	Protospacer
*******.****.************.    *

111. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 8, identity: 0.75

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gcccgcttgagccgccggacctccttcagcca	Protospacer
 ******.****.************.*   *

112. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 8, identity: 0.75

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gcccgcgcgagcggccggacctccgacccggt	Protospacer
 ***** ***** ***********  *.*. *

113. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020372 (Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence) position: , mismatch: 8, identity: 0.75

-ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
atgtcgat-gagctgccggatctcctcgtcacg	Protospacer
 . .** * ***********.****** ****

114. spacer 6.67|960334|32|NC_015387|CRISPRCasFinder,CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 8, identity: 0.75

tccacggtctcctccaggaccgcgccccggtc	CRISPR spacer
gccacggtctcctccacgagcgcgcgcggcga	Protospacer
 *************** ** ***** * *

115. spacer 6.67|960334|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP018075 (Streptomyces venezuelae strain NRRL B-65442 plasmid, complete sequence) position: , mismatch: 8, identity: 0.75

tccacggtctcctccaggaccgcgcc--ccggtc	CRISPR spacer
gtgacggtcacctccaggatcgcgccgtccag--	Protospacer
 . ****** *********.******  **.*

116. spacer 6.76|960882|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

tctagcccctgcaacacaaagccccgccccca	CRISPR spacer
catagcccccgcaacacaaaaccccgccgttg	Protospacer
. *******.**********.******* ...

117. spacer 6.76|960882|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP016453 (Sphingobium sp. RAC03 plasmid pBSY17_1, complete sequence) position: , mismatch: 8, identity: 0.75

tctagcccctgcaacacaaagccccgccccca	CRISPR spacer
tcatacccctgcaacgcaaagccgcgcccatc	Protospacer
**  .**********.******* ***** .

118. spacer 6.78|961004|33|NC_015387|CRISPRCasFinder,CRT matches to MK937595 (Streptomyces phage Dubu, complete genome) position: , mismatch: 8, identity: 0.758

ggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
agtgctccgcgcccgtctccgggtccacggcgt	Protospacer
.*  **** ************ ********. .

119. spacer 6.78|961004|33|NC_015387|CRISPRCasFinder,CRT matches to MG945161 (UNVERIFIED: Microviridae sp. isolate 405-1507, complete genome) position: , mismatch: 8, identity: 0.758

ggacctcctcgcccgtctccgcgtc----cacggttc	CRISPR spacer
agacctcctcggccgtcttcgcgtcccaacgcg----	Protospacer
.********** ******.******    *.**

120. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR134454 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence) position: , mismatch: 8, identity: 0.75

aacgagcaccgcgccgcgatcatcctgaacgc---	CRISPR spacer
aacgagcaccgcgccgagctca---tggacatggt	Protospacer
**************** * ***   **.**..

121. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP036221 (Mycobacterium avium subsp. hominissuis strain mc2 2500 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
cgcgaggcccgcgccgcgatcatccgcatcac	Protospacer
 .****  *****************  * *.*

122. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP040253 (Mycobacterium avium subsp. hominissuis strain 101115 plasmid pMARIA, complete sequence) position: , mismatch: 8, identity: 0.75

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
cgcgaggcccgcgccgcgatcatccgcatcac	Protospacer
 .****  *****************  * *.*

123. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP040245 (Mycobacterium avium subsp. hominissuis strain 101034 plasmid pMARIA, complete sequence) position: , mismatch: 8, identity: 0.75

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
cgcgaggcccgcgccgcgatcatccgcatcac	Protospacer
 .****  *****************  * *.*

124. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP040249 (Mycobacterium avium subsp. hominissuis strain 101174 plasmid pMARIA, complete sequence) position: , mismatch: 8, identity: 0.75

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
cgcgaggcccgcgccgcgatcatccgcatcac	Protospacer
 .****  *****************  * *.*

125. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MN103533 (Mycobacterium phage Weirdo19, complete genome) position: , mismatch: 8, identity: 0.75

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aacgagcaccacgtcgcgatcatgggcgacga	Protospacer
**********.**.*********    .***

126. spacer 6.81|961188|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP039918 (Agrobacterium tumefaciens strain CFBP6626 plasmid pAtCFBP6626a, complete sequence) position: , mismatch: 8, identity: 0.75

cttgcccgcgcgcgtgaggttgaggctatcga	CRISPR spacer
gtcgcccgcgcgcgcgacgttgaggcgctctc	Protospacer
 *.***********.** ********  **

127. spacer 6.81|961188|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP039905 (Agrobacterium tumefaciens strain CFBP6623 plasmid pAtCFBP6623a, complete sequence) position: , mismatch: 8, identity: 0.75

cttgcccgcgcgcgtgaggttgaggctatcga	CRISPR spacer
gtcgcccgcgcgcgcgacgttgaggcgctctc	Protospacer
 *.***********.** ********  **

128. spacer 6.81|961188|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP039909 (Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence) position: , mismatch: 8, identity: 0.75

cttgcccgcgcgcgtgaggttgaggctatcga	CRISPR spacer
gtcgcccgcgcgcgcgacgttgaggcgctctc	Protospacer
 *.***********.** ********  **

129. spacer 6.83|961310|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.75

tgctccacaggccgagcagcgtgcgggattgc	CRISPR spacer
cgctccacaggccgagccgcgtgccaatctgg	Protospacer
.**************** ****** .. .**

130. spacer 6.83|961310|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

tgctccacaggccgagcagcgtgcgggattgc	CRISPR spacer
aggcgcacaggccgggcagcctgcgggacttc	Protospacer
 * . *********.***** *******.* *

131. spacer 6.84|961371|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP044989 (Deinococcus sp. AJ005 plasmid p380k, complete sequence) position: , mismatch: 8, identity: 0.75

-----agggtgccgcttacctacaagagcgtcaaggt	CRISPR spacer
gtctgag-----cggttacctacaagagcgtcacggc	Protospacer
     **     ** ****************** **.

132. spacer 6.87|961554|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.75

ctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
gggccgcgcccttgcctcgccgatccgggcga	Protospacer
  *  ***** ************* **** *

133. spacer 6.95|962042|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020716 (Cnuibacter physcomitrellae strain XA(T) plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

agtgggaggaagccaaagccaccagggccgtt	CRISPR spacer
acacagaggaagccaaagccaccaccgccgag	Protospacer
*   .*******************  ****

134. spacer 6.96|962103|32|NC_015387|CRISPRCasFinder,CRT matches to CP054922 (Streptomyces sp. NA03103 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ccctcctggactggttacggcaggacccgccc	CRISPR spacer
gcccgctggactggttgcggcaggagccgtgg	Protospacer
 **. ***********.******** ***.

135. spacer 6.98|962225|33|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 8, identity: 0.758

aacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
agcgccttgagcagcacgctgaacgcgagcagg	Protospacer
*.*********** *****.*******  *. .

136. spacer 6.98|962225|33|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP033583 (Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence) position: , mismatch: 8, identity: 0.758

aacgccttgagcaccacgccgaacgc---gtccgta	CRISPR spacer
gccgccttgagctccgcgccgaacgcggagccc---	Protospacer
. ********** **.**********   *.**

137. spacer 6.98|962225|33|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP010991 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-2, complete sequence) position: , mismatch: 8, identity: 0.758

aacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
agcgccttgagcagcacgctgaacgcgagcagg	Protospacer
*.*********** *****.*******  *. .

138. spacer 6.98|962225|33|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP011667 (Streptomyces sp. Mg1 plasmid pSMg1-3, complete sequence) position: , mismatch: 8, identity: 0.758

aacgccttgagcaccacgccgaacgc---gtccgta	CRISPR spacer
gccgccttgagctccgcgccgaacgcggagccc---	Protospacer
. ********** **.**********   *.**

139. spacer 6.105|962653|32|NC_015387|CRISPRCasFinder,CRT matches to KX758539 (Mycobacterium phage Jaan, complete genome) position: , mismatch: 8, identity: 0.75

ctgggagccgtcagcgggctctccatcggtta	CRISPR spacer
cggatcgccgccagcgggctctccttcgggga	Protospacer
* *.  ****.************* ****  *

140. spacer 6.105|962653|32|NC_015387|CRISPRCasFinder,CRT matches to MN703408 (Mycobacterium phage Phaded, complete genome) position: , mismatch: 8, identity: 0.75

ctgggagccgtcagcgggctctccatcggtta	CRISPR spacer
cggatcgccgccagcgggctctccttcgggga	Protospacer
* *.  ****.************* ****  *

141. spacer 6.105|962653|32|NC_015387|CRISPRCasFinder,CRT matches to NC_031279 (Mycobacterium phage Bactobuster, complete genome) position: , mismatch: 8, identity: 0.75

ctgggagccgtcagcgggctctccatcggtta	CRISPR spacer
cggatcgccgccagcgggctctccttcgggga	Protospacer
* *.  ****.************* ****  *

142. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
gaagacagtgcgttcatcacccgcgaactcgc	Protospacer
*  * * ******** ***.**********

143. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
atcggcaagccgcgcaccatgcgcccggcgat	Protospacer
 *** ** *****************  * *..

144. spacer 10.15|2084521|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053565 (Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

ggcgtggctggccgagcgcggcatggacatagaga	CRISPR spacer
ggcgtggctggccgagcgcggcatcgagctgctcg	Protospacer
************************ **  *.   .

145. spacer 10.15|2084521|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.771

-ggcgtggctggccgagcgcggcatggacatagaga	CRISPR spacer
tgacg-ggcaggccgagcgcggcatggagatggtcg	Protospacer
 *.** *** ****************** **.*  .

146. spacer 2.16|275168|34|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 9, identity: 0.735

gtgcgggatcgcctcatggccctctccggggagc	CRISPR spacer
gtcggggatggcttcatggccctctccgccaaag	Protospacer
**  ***** **.***************  .*.

147. spacer 2.16|275168|34|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 9, identity: 0.735

gtgcgggatcgcctcatggccctctccggggagc	CRISPR spacer
gtcggggatggcttcatggccctctccgccaaag	Protospacer
**  ***** **.***************  .*.

148. spacer 2.21|275532|34|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 9, identity: 0.735

acggggtgcccgcgcacgtgcccagcctgagcga	CRISPR spacer
ccgacgagcccgcgcccgtgaccagcctgaggag	Protospacer
 **. * ******** **** ********** ..

149. spacer 2.31|276261|37|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 9, identity: 0.757

gtccgccaggtgcggcgcgacgcggtcca-ggacccac	CRISPR spacer
tcccgccaggtccgacgcgacgcggtccaccggctcg-	Protospacer
 .********* **.**************  *.*.*.

150. spacer 2.42|277063|36|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.75

ttcacgccgtgcgcgtcctgcacgagaagcacgcgg	CRISPR spacer
cttccgccgtgcgcgtcctgatcgagaagcggaagg	Protospacer
.*. ****************  ********. . **

151. spacer 2.44|277210|36|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.75

ttcacgccgtgcgcgtcctgcacgagaagcacgcgg	CRISPR spacer
cttccgccgtgcgcgtcctgatcgagaagcggaagg	Protospacer
.*. ****************  ********. . **

152. spacer 6.2|959783|33|NC_015387|PILER-CR matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gcctgggccgcaccgatccaggccgcccaagcg	CRISPR spacer
atctggcccgcaccgatccaggctgcgaggccg	Protospacer
..**** ****************.**  .. **

153. spacer 6.6|960027|33|NC_015387|PILER-CR matches to CP041517 (Bacillus aryabhattai strain KNU10 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

gccttcactaaccagaaaaacgaagaaaaaagc	CRISPR spacer
aaaaacacttaccagaaaaacgaaggaaattgc	Protospacer
.    **** ***************.***  **

154. spacer 6.7|960088|34|NC_015387|PILER-CR matches to NZ_CP014675 (Kozakia baliensis strain DSM 14400 plasmid pKB14400_1, complete sequence) position: , mismatch: 9, identity: 0.735

gtggctgcggcgcgtggctcacgcgtgcggggtg	CRISPR spacer
gccgaagcggggcgtggcgcacgcgtgcggcgga	Protospacer
*. *  **** ******* *********** * .

155. spacer 6.8|960150|33|NC_015387|PILER-CR matches to NZ_CP029358 (Azospirillum sp. CFH 70021 plasmid unnamed3) position: , mismatch: 9, identity: 0.727

ggcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
gccgcggctcgaggtcgtccagcacgttgacgt	Protospacer
* *********** .***********. .*  .

156. spacer 6.9|960211|33|NC_015387|PILER-CR matches to NZ_CP007516 (Rubrobacter radiotolerans strain RSPS-4 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.727

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gagccgcacgagctcccggacctcctcccgcag	Protospacer
*  **** ****** *************.

157. spacer 6.9|960211|33|NC_015387|PILER-CR matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 9, identity: 0.727

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
accccgcttgagccgccggacctccttgagcca	Protospacer
.*******.****.************.    *

158. spacer 6.9|960211|33|NC_015387|PILER-CR matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.727

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gacgtcctcgaccagccggacctcctcctcgaa	Protospacer
* * . ***** * ****************.

159. spacer 6.9|960211|33|NC_015387|PILER-CR matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 9, identity: 0.727

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
agcccgcttgagccgccggacctccttcagcca	Protospacer
. ******.****.************.*   *

160. spacer 6.20|960881|33|NC_015387|PILER-CR matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

ctctagcccctgcaacacaaagccccgccccca	CRISPR spacer
tcatagcccccgcaacacaaaaccccgccgttg	Protospacer
.. *******.**********.******* ...

161. spacer 6.22|961003|34|NC_015387|PILER-CR matches to MK937595 (Streptomyces phage Dubu, complete genome) position: , mismatch: 9, identity: 0.735

aggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
cagtgctccgcgcccgtctccgggtccacggcgt	Protospacer
 .*  **** ************ ********. .

162. spacer 6.22|961003|34|NC_015387|PILER-CR matches to MG945161 (UNVERIFIED: Microviridae sp. isolate 405-1507, complete genome) position: , mismatch: 9, identity: 0.735

aggacctcctcgcccgtctccgcgtc----cacggttc	CRISPR spacer
tagacctcctcggccgtcttcgcgtcccaacgcg----	Protospacer
 .********** ******.******    *.**

163. spacer 6.23|961065|33|NC_015387|PILER-CR matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 9, identity: 0.727

gaacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gccggctgcccgcgcggcgatcatcctgaaggc	Protospacer
*   *    ****** ************** **

164. spacer 6.23|961065|33|NC_015387|PILER-CR matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 9, identity: 0.727

gaacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gccggctgcccgcgcggcgatcatcctgaaggc	Protospacer
*   *    ****** ************** **

165. spacer 6.31|961553|33|NC_015387|PILER-CR matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.727

gctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
gcgcctgcgccattgcctcgacgatgcaggccg	Protospacer
**    ************** ******.**

166. spacer 6.31|961553|33|NC_015387|PILER-CR matches to NZ_CP031163 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdI, complete sequence) position: , mismatch: 9, identity: 0.727

gctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
gcccctgcgcccttgcctcaccgatgcgggcaa	Protospacer
**.   ***** *******.********** .

167. spacer 6.42|962224|34|NC_015387|PILER-CR matches to NZ_CP010991 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-2, complete sequence) position: , mismatch: 9, identity: 0.735

gaacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
cagcgccttgagcagcacgctgaacgcgagcagg	Protospacer
 *.*********** *****.*******  *. .

168. spacer 6.42|962224|34|NC_015387|PILER-CR matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 9, identity: 0.735

gaacgccttgagcaccacgccgaacgcgtccgta	CRISPR spacer
cagcgccttgagcagcacgctgaacgcgagcagg	Protospacer
 *.*********** *****.*******  *. .

169. spacer 6.42|962224|34|NC_015387|PILER-CR matches to NZ_CP011667 (Streptomyces sp. Mg1 plasmid pSMg1-3, complete sequence) position: , mismatch: 9, identity: 0.735

gaacgccttgagcaccacgccgaacgc---gtccgta	CRISPR spacer
cgccgccttgagctccgcgccgaacgcggagccc---	Protospacer
 . ********** **.**********   *.**

170. spacer 6.42|962224|34|NC_015387|PILER-CR matches to NZ_CP033583 (Streptomyces sp. ADI95-16 plasmid pADI95-16b, complete sequence) position: , mismatch: 9, identity: 0.735

gaacgccttgagcaccacgccgaacgc---gtccgta	CRISPR spacer
cgccgccttgagctccgcgccgaacgcggagccc---	Protospacer
 . ********** **.**********   *.**

171. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
catcggcaagccgcgcaccatgcgcccggcgat	Protospacer
  *** ** *****************  * *..

172. spacer 6.58|959784|32|NC_015387|CRISPRCasFinder,CRT matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 9, identity: 0.719

cctgggccgcaccgatccaggccgcccaagcg	CRISPR spacer
ggcgacgcccatcgatccaggccgctcaagcg	Protospacer
  .*.  * **.*************.******

173. spacer 6.58|959784|32|NC_015387|CRISPRCasFinder,CRT matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 9, identity: 0.719

cctgggccgcaccgatccaggccgcccaagcg	CRISPR spacer
ggcgacgcccatcgatccaggccgctcaagcg	Protospacer
  .*.  * **.*************.******

174. spacer 6.58|959784|32|NC_015387|CRISPRCasFinder,CRT matches to NC_014723 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH02, complete sequence) position: , mismatch: 9, identity: 0.719

cctgggccgcaccgatccaggccgcccaagcg	CRISPR spacer
ggcgacgcccatcgatccaggccgctcaagcg	Protospacer
  .*.  * **.*************.******

175. spacer 6.58|959784|32|NC_015387|CRISPRCasFinder,CRT matches to NC_015065 (Granulicella tundricola MP5ACTX9 plasmid pACIX902, complete sequence) position: , mismatch: 9, identity: 0.719

cctgggccgcaccgatccaggccgcccaagcg	CRISPR spacer
ctcaacccgcaccgatcccggccgcacaaact	Protospacer
*.... ************ ****** ***.*

176. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to CAJDKA010000002 (Enterococcus phage 163 genome assembly, contig: phage163-genome, whole genome shotgun sequence) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

177. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to MT856905 (Enterococcus phage vB_EfaM_A2, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

178. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to MW004544 (Enterococcus phage EFGrKN, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

179. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to MN241318 (Enterococcus phage PEf771, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

180. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to NC_029009 (Enterococcus phage EFDG1, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

181. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to MT909815 (Enterococcus phage iF6, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atacaaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

182. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to KY549443 (Enterococcus phage EFP01, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

183. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to MH880817 (Enterococcus phage EfV12-phi1, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

184. spacer 6.59|959845|32|NC_015387|CRISPRCasFinder,CRT matches to MN027503 (Enterococcus phage vB_OCPT_Ben, complete genome) position: , mismatch: 9, identity: 0.719

agaaggcgcaaacgcaagaaaaccccgtataa	CRISPR spacer
atataaatgaaacgcaagaaaaccccacataa	Protospacer
* * ..   *****************..****

185. spacer 6.63|960089|33|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP014675 (Kozakia baliensis strain DSM 14400 plasmid pKB14400_1, complete sequence) position: , mismatch: 9, identity: 0.727

tggctgcggcgcgtggctcacgcgtgcggggtg	CRISPR spacer
ccgaagcggggcgtggcgcacgcgtgcggcgga	Protospacer
. *  **** ******* *********** * .

186. spacer 6.64|960151|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP024427 (Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence) position: , mismatch: 9, identity: 0.719

gcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
cggcggctgaagcccgtccagcacgctgagtt	Protospacer
  ****** .**************** .*...

187. spacer 6.64|960151|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020443 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

gcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
cggcggctgaagcccgtccagcacgctgagtt	Protospacer
  ****** .**************** .*...

188. spacer 6.64|960151|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP029358 (Azospirillum sp. CFH 70021 plasmid unnamed3) position: , mismatch: 9, identity: 0.719

gcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
ccgcggctcgaggtcgtccagcacgttgacgt	Protospacer
 *********** .***********. .*  .

189. spacer 6.64|960151|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

gcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
cggcggctgaagcccgtccagcacgctgagtt	Protospacer
  ****** .**************** .*...

190. spacer 6.64|960151|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

gcgcggctcgagcccgtccagca-----cgcaaaacc	CRISPR spacer
gcgcggctcgagccggtcgagcagcgcctgcg-----	Protospacer
************** *** ****     .**.

191. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP007516 (Rubrobacter radiotolerans strain RSPS-4 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
agccgcacgagctcccggacctcctcccgcag	Protospacer
  **** ****** *************.

192. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
acgtcctcgaccagccggacctcctcctcgaa	Protospacer
 * . ***** * ****************.

193. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR134452 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 10, complete sequence) position: , mismatch: 9, identity: 0.719

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
acgcgcgcgagctgacggacctcctcgacgag	Protospacer
 * *** ******* ***********  *.

194. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 9, identity: 0.719

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gcccgcgcgagcggccggacctccagcccggc	Protospacer
 ***** ***** ***********  *.*. .

195. spacer 6.68|960395|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP032928 (Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence) position: , mismatch: 9, identity: 0.719

tcttcgtggaggcgggttgggctgaacccatt	CRISPR spacer
gcttcgtggacgcgggttgggttgagatcggc	Protospacer
 ********* **********.***. .*. .

196. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to MG198779 (Arthrobacter phage Urla, complete genome) position: , mismatch: 9, identity: 0.719

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
aacgagcagcgggccgcgatcatcgagggtcg	Protospacer
******** ** ************  *...

197. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 9, identity: 0.719

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gacgtgcaccgggccgcgatcatcaccggctc	Protospacer
.*** ****** ************ . ..* *

198. spacer 6.84|961371|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP021126 (Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence) position: , mismatch: 9, identity: 0.719

agggtgccgcttacctacaagagcgtcaaggt	CRISPR spacer
ttcctgccggttacctgcaagagcgtcagcgc	Protospacer
    ***** ******.***********. *.

199. spacer 6.87|961554|32|NC_015387|CRISPRCasFinder,CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.719

ctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
gtagagcgccagtgcctcgtcgatgcgcccca	Protospacer
 *.******** *******.*******

200. spacer 6.87|961554|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.719

ctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
cgcctgcgccattgcctcgacgatgcaggccg	Protospacer
*    ************** ******.**

201. spacer 6.87|961554|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP031163 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdI, complete sequence) position: , mismatch: 9, identity: 0.719

ctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
cccctgcgcccttgcctcaccgatgcgggcaa	Protospacer
*.   ***** *******.********** .

202. spacer 6.87|961554|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020445 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

ctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
gtcaattcccatcgcctcgccgatccggggga	Protospacer
 * .* . ****.*********** ******

203. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NC_015057 (Granulicella tundricola MP5ACTX9 plasmid pACIX901, complete sequence) position: , mismatch: 9, identity: 0.719

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
cctgcggcgtcatagccgatggcctccagctt	Protospacer
.****** **** ***********.  . * *

204. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MN175603 (Microbacterium phage Tyrumbra, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

205. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MN586042 (Microbacterium phage Jayden, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

206. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MN813684 (Microbacterium phage Terij, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggcgaccg	Protospacer
  **** *.****************.   **.

207. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MH155873 (Microbacterium phage Paschalis, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

208. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MH590600 (Microbacterium phage KaiHaiDragon, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

209. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MH271312 (Microbacterium phage RobsFeet, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

210. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MT818415 (Microbacterium phage Scumberland, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

211. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to NC_047993 (Microbacterium phage Quhwah, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

212. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MN062719 (Microbacterium phage PiperSansNom, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

213. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MN444877 (Microbacterium phage Antares, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

214. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to NC_047988 (Microbacterium phage Metamorphoo, complete genome) position: , mismatch: 9, identity: 0.719

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggctcccg	Protospacer
  **** *.****************. ..**.

215. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
ccgagcacgtcgcgcacgatgcgccgcggcac	Protospacer
.. . ****.******* *********** .*

216. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.719

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
gagggcacgccgcgcacccggcgccgcgccgt	Protospacer
   * *************  ********  *.

217. spacer 2.5|274374|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.714

gcgggggtcgcgcaccgggcggacgcgggggacct	CRISPR spacer
accgactgggcggaccgggcggacgcgggggtccc	Protospacer
.* *.    *** ****************** **.

218. spacer 2.12|274877|35|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.714

ctggatgaccgcgcggcgctcaccgcgttgtgcgg	CRISPR spacer
attagtgaccgcgcggcgctcgccgcgctgccggt	Protospacer
 * ..****************.*****.**.  *

219. spacer 2.31|276261|37|NC_015387|PILER-CR,CRISPRCasFinder,CRT matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 10, identity: 0.73

gtccgccaggtgcggcgcgacgcggtccaggacccac	CRISPR spacer
gcagcgccggtgcagcgcgtcgcggtccaggacccgt	Protospacer
*.    * *****.***** ***************..

220. spacer 6.8|960150|33|NC_015387|PILER-CR matches to NZ_CP024427 (Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence) position: , mismatch: 10, identity: 0.697

ggcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
ccggcggctgaagcccgtccagcacgctgagtt	Protospacer
   ****** .**************** .*...

221. spacer 6.8|960150|33|NC_015387|PILER-CR matches to NZ_CP020443 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.697

ggcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
tcggcggctgaagcccgtccagcacgctgagtt	Protospacer
   ****** .**************** .*...

222. spacer 6.8|960150|33|NC_015387|PILER-CR matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.697

ggcgcggctcgagcccgtccagcacgcaaaacc	CRISPR spacer
ccggcggctgaagcccgtccagcacgctgagtt	Protospacer
   ****** .**************** .*...

223. spacer 6.9|960211|33|NC_015387|PILER-CR matches to NZ_LR594660 (Variovorax sp. PBL-H6 plasmid 2) position: , mismatch: 10, identity: 0.697

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gagaagctcgagttgccggacctcatcctggag	Protospacer
*    *******.*********** **** .

224. spacer 6.9|960211|33|NC_015387|PILER-CR matches to NZ_LR594667 (Variovorax sp. SRS16 plasmid 2) position: , mismatch: 10, identity: 0.697

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gagaagctcgagttgccggacctcatcctggag	Protospacer
*    *******.*********** **** .

225. spacer 6.9|960211|33|NC_015387|PILER-CR matches to NZ_LR594690 (Variovorax sp. WDL1 plasmid 2) position: , mismatch: 10, identity: 0.697

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gagaagctcgagttgccggacctcatcctggag	Protospacer
*    *******.*********** **** .

226. spacer 6.9|960211|33|NC_015387|PILER-CR matches to NZ_LR594672 (Variovorax sp. PBL-E5 plasmid 2) position: , mismatch: 10, identity: 0.697

gccccgctcgagctgccggacctcctcctcact	CRISPR spacer
gagaagctcgagttgccggacctcatcctggag	Protospacer
*    *******.*********** **** .

227. spacer 6.12|960394|33|NC_015387|PILER-CR matches to NZ_CP032928 (Agrobacterium tumefaciens strain 1D1460 plasmid pAt1D1460, complete sequence) position: , mismatch: 10, identity: 0.697

gtcttcgtggaggcgggttgggctgaacccatt	CRISPR spacer
cgcttcgtggacgcgggttgggttgagatcggc	Protospacer
  ********* **********.***. .*. .

228. spacer 6.23|961065|33|NC_015387|PILER-CR matches to MG198779 (Arthrobacter phage Urla, complete genome) position: , mismatch: 10, identity: 0.697

gaacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
caacgagcagcgggccgcgatcatcgagggtcg	Protospacer
 ******** ** ************  *...

229. spacer 6.28|961370|33|NC_015387|PILER-CR matches to NZ_CP021126 (Rhizobium sp. Kim5 plasmid pRetKim5b, complete sequence) position: , mismatch: 10, identity: 0.697

gagggtgccgcttacctacaagagcgtcaaggt	CRISPR spacer
tttcctgccggttacctgcaagagcgtcagcgc	Protospacer
     ***** ******.***********. *.

230. spacer 6.31|961553|33|NC_015387|PILER-CR matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.697

gctggagcgccattgcctcgccgatgcgggggc	CRISPR spacer
cgtagagcgccagtgcctcgtcgatgcgcccca	Protospacer
  *.******** *******.*******

231. spacer 6.54|962957|33|NC_015387|PILER-CR matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.697

gttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
accgagcacgtcgcgcacgatgcgccgcggcac	Protospacer
... . ****.******* *********** .*

232. spacer 6.60|959906|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP016476 (Synechococcus sp. PCC 7003 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

tacctggacccaccccaaacacccgaaacgaa	CRISPR spacer
tacctagaccaaccccaaacacctaatcatcc	Protospacer
*****.**** ************..*

233. spacer 6.62|960028|32|NC_015387|CRISPRCasFinder,CRT matches to KF929199 (Staphylococcus phage vB_SepS_SEP9, complete genome) position: , mismatch: 10, identity: 0.688

ccttcactaaccagaaaaacgaagaaaaaagc	CRISPR spacer
atgttgttaataagaaaaacgaagaaaaaaca	Protospacer
 . *...***. ******************

234. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR594660 (Variovorax sp. PBL-H6 plasmid 2) position: , mismatch: 10, identity: 0.688

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
agaagctcgagttgccggacctcatcctggag	Protospacer
    *******.*********** **** .

235. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR594667 (Variovorax sp. SRS16 plasmid 2) position: , mismatch: 10, identity: 0.688

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
agaagctcgagttgccggacctcatcctggag	Protospacer
    *******.*********** **** .

236. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR594690 (Variovorax sp. WDL1 plasmid 2) position: , mismatch: 10, identity: 0.688

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
agaagctcgagttgccggacctcatcctggag	Protospacer
    *******.*********** **** .

237. spacer 6.65|960212|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR594672 (Variovorax sp. PBL-E5 plasmid 2) position: , mismatch: 10, identity: 0.688

ccccgctcgagctgccggacctcctcctcact	CRISPR spacer
agaagctcgagttgccggacctcatcctggag	Protospacer
    *******.*********** **** .

238. spacer 6.76|960882|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

tctagcccctgcaacacaaagccccgccccca	CRISPR spacer
gttcaggcctgcaacgcaaagacccgccccat	Protospacer
 .* .  ********.***** ********

239. spacer 6.76|960882|32|NC_015387|CRISPRCasFinder,CRT matches to NC_016567 (Vibrio phage SIO-2, complete genome) position: , mismatch: 10, identity: 0.688

tctagcccctgcaacacaaagccccgccccca	CRISPR spacer
ggcgttccctgcaaaacaacgccccgccctga	Protospacer
  .. .******** **** *********. *

240. spacer 6.78|961004|33|NC_015387|CRISPRCasFinder,CRT matches to DQ163916 (Bacteriophage M6, complete genome) position: , mismatch: 10, identity: 0.697

ggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
ccgactccttgcccgtctccgggtccacgtagt	Protospacer
  . *****.*********** *******   .

241. spacer 6.78|961004|33|NC_015387|CRISPRCasFinder,CRT matches to NC_007809 (Pseudomonas phage M6, complete genome) position: , mismatch: 10, identity: 0.697

ggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
ccgactccttgcccgtctccgggtccacgtagt	Protospacer
  . *****.*********** *******   .

242. spacer 6.78|961004|33|NC_015387|CRISPRCasFinder,CRT matches to MN183284 (Microbacterium phage Mashley, complete genome) position: , mismatch: 10, identity: 0.697

ggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
cgtactcctcgcccgtctcctcgtcgacctccg	Protospacer
 *  **************** **** **  ..

243. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP024582 (Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gacgagtacggcgccgcgatcatcaacggcat	Protospacer
.*****.** **************   ..*..

244. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LT984809 (Cupriavidus taiwanensis isolate Cupriavidus taiwanensis STM 8555 plasmid I, complete sequence) position: , mismatch: 10, identity: 0.688

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gacgagcaccgtggcgcgatcatcgacctcat	Protospacer
.**********.* **********     *..

245. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NC_008545 (Burkholderia cenocepacia HI2424 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gccgagcgccgcgccgcgttcatccgcggcaa	Protospacer
. *****.********** ******  ..*.

246. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP025188 (Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence) position: , mismatch: 10, identity: 0.688

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gacgagtacggcgccgcgatcatcaacggcat	Protospacer
.*****.** **************   ..*..

247. spacer 6.79|961066|32|NC_015387|CRISPRCasFinder,CRT matches to EF523948 (Burkholderia phage BcepGomr, complete genome) position: , mismatch: 10, identity: 0.688

aacgagcaccgcgccgcgatcatcctgaacgc	CRISPR spacer
gaaattttccgcgcctcgatcatccggaacga	Protospacer
.* .  . ******* ********* *****

248. spacer 6.85|961432|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020926 (Sphingobium yanoikuyae strain SHJ plasmid pSES220, complete sequence) position: , mismatch: 10, identity: 0.688

tttagtctcgagctcgctgctccgcgcctcag	CRISPR spacer
cagctcttcgagctcgctgcgccgcgcctcga	Protospacer
.    ..************* *********..

249. spacer 6.85|961432|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_AP018666 (Sphingobium amiense strain DSM 16289 plasmid pSAMIE_3, complete sequence) position: , mismatch: 10, identity: 0.688

tttagtctcgagctcgctgctccgcgcctcag	CRISPR spacer
cagctcttcgagctcgctgcgccgcgcctcga	Protospacer
.    ..************* *********..

250. spacer 6.85|961432|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP053023 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-B-Sy, complete sequence) position: , mismatch: 10, identity: 0.688

tttagtctcgagctcgctgctccgcgcctcag	CRISPR spacer
cagctcttcgagctcgctgcgccgcgcctcga	Protospacer
.    ..************* *********..

251. spacer 6.85|961432|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP022747 (Sphingobium hydrophobicum strain C1 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

tttagtctcgagctcgctgctccgcgcctcag	CRISPR spacer
cagctcttcgagctcgctgcgccgcgcctcga	Protospacer
.    ..************* *********..

252. spacer 6.86|961493|32|NC_015387|CRISPRCasFinder,CRT matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 10, identity: 0.688

cacaacgtaacgcccggaatgtgcctgagggg	CRISPR spacer
gacaacgtaacgcccgaaatgcgcatctacaa	Protospacer
 ***************.****.** *  . ..

253. spacer 6.95|962042|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP013558 (Rhizobium phaseoli strain N841 plasmid pRphaN841a, complete sequence) position: , mismatch: 10, identity: 0.688

agtgggaggaagccaaagccaccagggccgtt	CRISPR spacer
tgatcgaggaagccaaagccatcaaggcgaag	Protospacer
 *   ****************.**.*** .

254. spacer 6.96|962103|32|NC_015387|CRISPRCasFinder,CRT matches to NC_019387 (Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence) position: , mismatch: 10, identity: 0.688

ccctcctggactggttacggcaggacccgccc	CRISPR spacer
tcctcctggaatgggtacggcagggggaggag	Protospacer
.********* *** *********.   *

255. spacer 6.97|962164|32|NC_015387|CRISPRCasFinder,CRT matches to NC_019387 (Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence) position: , mismatch: 10, identity: 0.688

tctgcggagtcagagccgatggcccgggccat	CRISPR spacer
cggtccaggtcaaagccgctggcccgggccag	Protospacer
.   * ..****.***** ************

256. spacer 6.100|962348|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_JX627580 (Methylobacterium oryzae CBMB20 plasmid pMOC1, complete sequence) position: , mismatch: 10, identity: 0.688

ggatcgaaatggacaaggccggatgggcgata	CRISPR spacer
cttgctaaatggacaaggctggatggccgtcg	Protospacer
    * *************.****** ** ..

257. spacer 6.103|962531|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 10, identity: 0.688

tctacgaattattatgcgaagaacttccgccc	CRISPR spacer
agtttgaattattttgagaagaacttcctgtg	Protospacer
  * .******** ** ***********  .

258. spacer 6.106|962714|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP023367 (Escherichia coli strain 1428 plasmid p111, complete sequence) position: , mismatch: 10, identity: 0.688

cccctgcgggaggtcacggtacgtgtgcgctc	CRISPR spacer
gccccgcgggagggcacggtacgtgctgatgt	Protospacer
 ***.******** ***********.  .. .

259. spacer 6.107|962775|32|NC_015387|CRISPRCasFinder,CRT matches to MK937606 (Microbacterium phage Margaery, complete genome) position: , mismatch: 10, identity: 0.688

gccgtccgtgcgttcctcatccgcgaactcca	CRISPR spacer
cgcgtcggcgcgttcctcatccgcggcgagcg	Protospacer
  **** *.****************.    *.

260. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NC_022539 (Xanthomonas citri pv. fuscans plasmid pla, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

261. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020984 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6990 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

262. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020986 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6992 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

263. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NC_013958 (Nitrosococcus halophilus Nc 4 plasmid pNHAL01, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc------	CRISPR spacer
ctcgccactcagcgcaccatgcgc------actttctg	Protospacer
.******* * *************      .*

264. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP021008 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6975 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

265. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020993 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

266. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020993 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

267. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
gccctgacggtgcgcaccatgcgccgcggcat	Protospacer
 .* . *** .****************** ..

268. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP021019 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

269. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP021017 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6991 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

270. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020982 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6989 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

271. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020982 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6989 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

272. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020990 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6996R plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

273. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020999 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6165 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

274. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP021002 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

275. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to CP021013 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP7767 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

276. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020980 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6988R plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

277. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP020988 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6994R plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
aaagccacgccgcgccccacgcgccgttttcc	Protospacer
   ************ ***.******.    *

278. spacer 7.7|1466414|38|NC_015387|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.737

cgcggccagcgcctcgccgacgccgagcatgtccagga	CRISPR spacer
cgcggcgagcgccgcgccgacgccgaggcctaacgcga	Protospacer
****** ****** *************  .   *. **

279. spacer 7.7|1466414|38|NC_015387|CRISPRCasFinder matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.737

cgcggccagcgcctcgccgacgccgagcatgtccagga	CRISPR spacer
ggccgccagcgcctcgccgacgccgcgcgcgagctcgg	Protospacer
 ** ********************* **..*  *  *.

280. spacer 7.61|1466415|38|NC_015387|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.737

gcggccagcgcctcgccgacgccgagcatgtccaggag	CRISPR spacer
gccgccagcgcctcgccgacgccgcgcgcgagctcggc	Protospacer
** ********************* **..*  *  *.

281. spacer 6.22|961003|34|NC_015387|PILER-CR matches to DQ163916 (Bacteriophage M6, complete genome) position: , mismatch: 11, identity: 0.676

aggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
tccgactccttgcccgtctccgggtccacgtagt	Protospacer
   . *****.*********** *******   .

282. spacer 6.22|961003|34|NC_015387|PILER-CR matches to NC_007809 (Pseudomonas phage M6, complete genome) position: , mismatch: 11, identity: 0.676

aggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
tccgactccttgcccgtctccgggtccacgtagt	Protospacer
   . *****.*********** *******   .

283. spacer 6.22|961003|34|NC_015387|PILER-CR matches to MN183284 (Microbacterium phage Mashley, complete genome) position: , mismatch: 11, identity: 0.676

aggacctcctcgcccgtctccgcgtccacggttc	CRISPR spacer
tcgtactcctcgcccgtctcctcgtcgacctccg	Protospacer
  *  **************** **** **  ..

284. spacer 6.50|962713|33|NC_015387|PILER-CR matches to NZ_CP023367 (Escherichia coli strain 1428 plasmid p111, complete sequence) position: , mismatch: 11, identity: 0.667

gcccctgcgggaggtcacggtacgtgtgcgctc	CRISPR spacer
agccccgcgggagggcacggtacgtgctgatgt	Protospacer
. ***.******** ***********.  .. .

285. spacer 6.85|961432|32|NC_015387|CRISPRCasFinder,CRT matches to NC_009507 (Sphingomonas wittichii RW1 plasmid pSWIT01, complete sequence) position: , mismatch: 11, identity: 0.656

tttagtctcgagctcgctgctccgcgcctcag	CRISPR spacer
cagctcttcgagctcgctgcgccgtgcctcga	Protospacer
.    ..************* ***.*****..

286. spacer 6.93|961920|32|NC_015387|CRISPRCasFinder,CRT matches to MN095770 (Serratia phage Slocum, complete genome) position: , mismatch: 11, identity: 0.656

gagtatccgcaagcacgtcaaaagcaaaagag	CRISPR spacer
cagtatccgcaaccacgtcaatagtgttcata	Protospacer
 *********** ******** **..   . .

287. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP044082 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence) position: , mismatch: 11, identity: 0.656

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
gcgatcaggccgcgcacgatgcgccgcgccat	Protospacer
 . ..** ********* **********  ..

288. spacer 6.110|962958|32|NC_015387|CRISPRCasFinder,CRT matches to NZ_CP031080 (Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence) position: , mismatch: 11, identity: 0.656

ttcgccacgccgcgcaccatgcgccgcggggc	CRISPR spacer
gcgatcaggccgcgcacgatgcgccgcgccat	Protospacer
 . ..** ********* **********  ..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015387

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection