CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_005296	Rhodopseudomonas palustris CGA009, complete genome	2 crisprs	csa3,WYL	0	1	2	0
NC_005297	Rhodopseudomonas palustris CGA009 plasmid pRPA, complete sequence	0 crisprs	NA	0	0	0	0

1. NC_005296

CRISPR-Cas detection and classification

Crispr_ID: NC_005296_1

• CRISPR_ID: NC_005296_1
• CRISPR_location: 2487767-2487845
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NC_005296_1

Consensus_repeat	Method
CGCGCATCTGAGATGCGCGATAAT	CRISPRCasFinder

spacers of NC_005296_1

>1.1|2487791|31|NC_005296|CRISPRCasFinder
TCTTGCACGCAAAGCCGGATCGTGGGATTAA

CRISPR arrays and Neighbor proteins around NC_005296_1

CRISPR arrays

The CRISPR arrays of NC_005296_1

>merge|NC_005296|1|2487767-2487845|CRISPRCasFinder
CGCGCATCTGAGATGCGCGATAATTCTTGCACGCAAAGCCGGATCGTGGGATTAACGCGCATCTGAGATGCGAGATAAT

>NC_005296|1|1|2487767-2487845|CRISPRCasFinder
CGCGCATCTGAGATGCGCGATAAT	TCTTGCACGCAAAGCCGGATCGTGGGATTAA
CGCGCATCTGAGATGCGAGATAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_005296.1|WP_011157764.1|2489713_2492842_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|350180
NC_005296.1|WP_162843685.1|2505356_2505500_-|hypothetical-protein	unknown	unknown	unknown
NC_005296.1|WP_011157766.1|2494677_2495862_-|hypothetical-protein	unknown	unknown	unknown
NC_005296.1|WP_011157768.1|2499275_2502677_-|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl|CDD|224000
NC_005296.1|WP_011157755.1|2475577_2477074_+|IMP-dehydrogenase	unknown	unknown	gnl|CDD|235507
NC_005296.1|WP_011157762.1|2486652_2487543_+|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|311449
NC_005296.1|WP_011157771.1|2506543_2510062_+|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|350769
NC_005296.1|WP_011157757.1|2478588_2479890_+|RsmB/NOP-family-class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl|CDD|223222
NC_005296.1|WP_011157761.1|2484201_2485770_+|recombinase-family-protein	unknown	unknown	gnl|CDD|214861
NC_005296.1|WP_009820572.1|2483745_2484126_-|hypothetical-protein	unknown	unknown	unknown
NC_005296.1|WP_011157767.1|2495914_2499256_-|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl|CDD|350684
NC_005296.1|WP_011157758.1|2480181_2481804_+|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl|CDD|234614
NC_005296.1|WP_042441021.1|2502676_2505289_-|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl|CDD|378929
NC_005296.1|WP_011157759.1|2482086_2483343_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271182
NC_005296.1|WP_011157770.1|2505625_2506510_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|379100
NC_005296.1|WP_009820574.1|2485766_2486651_+|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|319268
NC_005296.1|WP_042441019.1|2487848_2489702_+|type-II-toxin-antitoxin-system-HipA-family-toxin	unknown	unknown	gnl|CDD|377920
NC_005296.1|WP_009820571.1|2483314_2483605_-|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl|CDD|283558
NC_005296.1|WP_011157756.1|2477372_2478398_+|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|176190
NC_005296.1|WP_011157765.1|2492831_2494688_-|phospholipase-D-family-protein	unknown	unknown	gnl|CDD|197273

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_005296.1|WP_011157770.1|2505625_2506510_+|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	2.4e-15	51.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_005296.1|WP_011157764.1|2489713_2492842_-|DEAD/DEAH-box-helicase	gnl|CDD|350180	cd18793, SF2_C_SNF, C-terminal helicase domain of the SNF family helicases. The Sucrose Non-Fermenting (SNF) family includes chromatin-remodeling factors, such as CHD proteins and SMARCA proteins, recombination proteins Rad54, and many others. They are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.	7.19889e-05
NC_005296.1|WP_011157768.1|2499275_2502677_-|UvrD-helicase-domain-containing-protein	gnl|CDD|224000	COG1074, RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair].	9.73324e-100
NC_005296.1|WP_011157755.1|2475577_2477074_+|IMP-dehydrogenase	gnl|CDD|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NC_005296.1|WP_011157762.1|2486652_2487543_+|ParB-N-terminal-domain-containing-protein	gnl|CDD|311449	pfam07506, RepB, RepB plasmid partitioning protein. This family includes proteins with sequence similarity to the RepB partitioning protein of the large Ti (tumor-inducing) plasmids of Agrobacterium tumefaciens.	7.58058e-41
NC_005296.1|WP_011157771.1|2506543_2510062_+|DUF3883-domain-containing-protein	gnl|CDD|350769	cd18011, DEXDc_RapA, DEXH-box helicase domain of RapA. In bacteria, RapA is an RNA polymerase (RNAP)-associated SWI2/SNF2 (switch/sucrose non-fermentable) protein that mediates RNAP recycling during transcription. The ATPase activity of RapA is stimulated by its interaction with RNAP and inhibited by its N-terminal domain. The conformational changes of RapA and its interaction with RNAP are essential for RNAP recycling. RapA is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.52162e-76
NC_005296.1|WP_011157757.1|2478588_2479890_+|RsmB/NOP-family-class-I-SAM-dependent-RNA-methyltransferase	gnl|CDD|223222	COG0144, Sun, tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis].	6.55318e-82
NC_005296.1|WP_011157761.1|2484201_2485770_+|recombinase-family-protein	gnl|CDD|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	3.23295e-29
NC_005296.1|WP_011157767.1|2495914_2499256_-|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|350684	cd17926, DEXHc_RE, DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins. This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	6.61322e-36
NC_005296.1|WP_011157758.1|2480181_2481804_+|glutamine-hydrolyzing-GMP-synthase	gnl|CDD|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_005296.1|WP_042441021.1|2502676_2505289_-|PD-(D/E)XK-nuclease-family-protein	gnl|CDD|378929	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	2.35841e-16
NC_005296.1|WP_011157759.1|2482086_2483343_+|tyrosine-type-recombinase/integrase	gnl|CDD|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.20097e-53
NC_005296.1|WP_011157770.1|2505625_2506510_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.67998e-12
NC_005296.1|WP_009820574.1|2485766_2486651_+|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|319268	cd16411, ParB_N_like, ParB N-terminal, parA -binding, domain of bacterial and plasmid parABS partitioning systems. This family represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	3.11322e-47
NC_005296.1|WP_042441019.1|2487848_2489702_+|type-II-toxin-antitoxin-system-HipA-family-toxin	gnl|CDD|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	2.19286e-48
NC_005296.1|WP_009820571.1|2483314_2483605_-|AlpA-family-phage-regulatory-protein	gnl|CDD|283558	pfam05930, Phage_AlpA, Prophage CP4-57 regulatory protein (AlpA). This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant, overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins.	1.41316e-14
NC_005296.1|WP_011157756.1|2477372_2478398_+|NADP-dependent-oxidoreductase	gnl|CDD|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	0
NC_005296.1|WP_011157765.1|2492831_2494688_-|phospholipase-D-family-protein	gnl|CDD|197273	cd09176, PLDc_unchar6, Putative catalytic domain of uncharacterized hypothetical proteins with one or two copies of the HKD motif. Putative catalytic domain of uncharacterized hypothetical proteins with similarity to phospholipase D (PLD, EC 3.1.4.4). PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain one or two copies of the HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily.	1.69405e-24

Protein sequences

>NC_005296.1|WP_011157762.1|2486652_2487543_+|ParB-N-terminal-domain-containing-protein
MSDTVKIAFERKILVLPIGELLATKALPAGVRESVKYRRIAASVAEVGLIEPLSIARQKGGSYLLLDGHMRLDALRFLGATEAPCVVADDDESFTYNKRVNRLATIQEHYMIVRALDRGVSEEKLARALNVDVKVIRQRRHLLAGISGDVAELLKDKPVGHHAFQKLRKMKPIRQLEVAELMVSANNYTVSYAKALLATSKPSDLHKPDELKKATGLSAEQMGRLEREMASVSEDYKELEVSYGDDMLVLVVASGFIERLLAKPEIEGFLAGRHPEFLENFRAIVQATSLDQSTTP
>NC_005296.1|WP_009820574.1|2485766_2486651_+|ParB/RepB/Spo0J-family-partition-protein
MSAPPPEIRSVPVDLITILNPRVRNKRIFQELVNSIAHLGLKKPITVSQRPGKTRFDLVCGQGRLEAFIALGQTEIPAIVIDAAEEDCYVMSLVENLARRQHSPLELVHAIGALSARGYSHPEIAAKVDFSVEYVSAICLLLDNGEEKLIAAVERGVIPHSIAMEIARAKEGEVQQALAQAYEEKSIPGNQVLAIRQIIEQRNTSGKQLHKRGSRVGRTQKPVTSESLIRAYQRETERQKLLIKRASLARSRLLFVANAMRRLLADDHFVTLLRAEGLSTLPRALAERIGPTKA
>NC_005296.1|WP_011157761.1|2484201_2485770_+|recombinase-family-protein
MNLSESVTAEASPRPPVRAAQYVRMSTEHQKYSTENQAEIIAQYAARRGFEIVKTYEDSGKSGLRLDGRLSLQQLIADVRGGQTDFKAILVYDVSRWGRFQDADESAYYEFICREAGIAVQYCAEQFENDGSLSATIIKSMKRAMAGEYSRELSVKVFTGQCRLIRLGFRQGGAAGFGLRRYLVDEHRQPKAVLNHGEQKSLQTDRVVLRPGPPEEIEVVRRLYRMFVVQRRTETEIATALNDEGILTDLGRPWTRGTVHQVLTNEKYIGNNVYNRASFKLKAKRVVNTPDMWVRGDGAFEAIVERDFFEAAQRIIQERSRRFTDEELLGRLSALLVEKGWLSGLVIDEVEDMPSSSTFRHRFGSLVRAYQLVGYAPSRDYRYIETNRTLRTLHPDVVAQVIADIGAAGGTVRRDPVTDLLHINDEFTASLVISRCHISPAGGLRWKVRFDSGLRPSITIVARMQEDNAAIHDYYLLPWLDVGTTPNLRLAPENGILLDAYRFDTLEAFFDLTRRVPLKVAA
>NC_005296.1|WP_009820572.1|2483745_2484126_-|hypothetical-protein
MSFSEKDRKLQSKTGNSFPSPQPNEPLAAAIAAALKAEFGNTPSAHKTVAQLTRSNERAVRNWFEGKNSPSGENLVILMRHSDLVLRTMLSLADRQDLVLAIGLASLRRQLVDAVAAIDGLPLAPD
>NC_005296.1|WP_009820571.1|2483314_2483605_-|AlpA-family-phage-regulatory-protein
MSTKSEALKKRMIRRHELRQIVPLADTTIYEMEQRGEFPRRFALTPRCVVWDLAEVEAWLTDRLATARRSPIDRAPHPDVRKRKARPVKAPDQARA
>NC_005296.1|WP_011157759.1|2482086_2483343_+|tyrosine-type-recombinase/integrase
MLTDVALKNLKPREKAYKVTDRDGLYVQVSTSGTLTFRLDYRLHGRRETLTLGKYGPSGLSLARAREATIDAKRAVFEGRSPAQEKQRDKRRIKEAKSFGEFGERWLVKAPMADSTRAMRRSIFERELLPVWKNRLLTEITPDDLRAHCGKIVDRGAPATAIHVRDILKQIYGFAILHGEKVANPADDVGPASIATFVPKDRSLSPTEIRVMLKQLDHVATLPTIRLGMRLFLLTMVRKSELQDAVWDEVDFENAVWTIPKERMKRSKAHNVYLSQQCLDIMIALKTCAGNSRYLLPSRYDADAPMSRATFNRVTYAVVERAQKEGLPLEPFTVHDLRRTGSTLLNELGFNSDWIEKCLAHEDGRSSRGVYNKAEYEHQRRHMMQEWSDIIDAWVAGQKRVPVLIPPSMPMLAPDPAL
>NC_005296.1|WP_011157758.1|2480181_2481804_+|glutamine-hydrolyzing-GMP-synthase
MTAPSTSSASSVVPSGADTSPHVAAIHEKILIVDFGSQVTQLIARRVREEGVYSEIVPFQKAEAAFAEMKPKAVILSGGPASVLDDNAPSAPMTILEAGVPVLGICYGEQTLAKQLGGTVEGGHHREFGRAQIEITDDCALFDGIWQKGGKYDVWMSHGDRVTKLPAGFRAVAQAPGSPISVIADDTRKFYAMQFHPEVVHTPDGAKLLSNFVRKVAGLTGDWTMRAFREEAIEKIRAQVGTGKVICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLLRKDEGKSVVDLFRHHYNIPLVHVDVSETFLGALKGVTDPEQKRKTIGKLFIDVFEAEARRVGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRALGRELGLPDVFVGRHPFPGPGLAIRCPGEITEEKLEILRNADAVYIDQIRKAGLYDVIWQAFAVLLPVRSVGVMGDGRTYDYVVGLRAVTSTDGMTADFYPFEMSFLGATATRIINEVKGVNRVVYDVTSKPPGTIEWE
>NC_005296.1|WP_011157757.1|2478588_2479890_+|RsmB/NOP-family-class-I-SAM-dependent-RNA-methyltransferase
MTPAARLSAAIDLIAAIDAQRIPAAKALKEWGTAHRYAGSGDRSAIAGVVWDVLRRRASCAYLMEADTPRARVLGMLKLERGMTAEAIAALCDGSRFAPEPLSDAEHAALSTRTLDGAPPHVAGDYPEWLDGALAEMFGEARVAEAAAMASRAPLDLRVNTLKASRDKELASLAHLGAKLAPWSPWGLRIELPADARNPGVQAEPDFIKGAVEVQDEGSQLAALLSAARPGEQVIDLCAGAGGKTLALAAMMQGKGRLIATDGDKRQLAPIHERLSRAGVHNAEVRAPKGDADPLADIKGSADLVLVDAPCTGTGTWRRNPDAKWRMRPGALEIRLKDQAEVLARAARLVKPGGRIAYITCSVLAPENTGQVQAFTAAHPEFAVVPPAEVAAALWDKAELFLAAAWISPEGLLMTPRRTGTDGFFVSVLKRQG
>NC_005296.1|WP_011157756.1|2477372_2478398_+|NADP-dependent-oxidoreductase
MPKGQRIVLASRPVGEPTPQNFRLEEFDVPAPGEGQVLLRTIWLSLDPYMRGRMSDGPSYAQPVPVGGVMEGGTVCEVIDSKSPGFAKGDIVLAHSGWATHAIADAKPLRKIDPALGPISTAVGVLGMPGMTAYTGLLDIGQPKEGETVVVAAASGAVGSAVGQIAKVKGARAIGIAGGKDKCDYVKQELGFDDCLDHRDPDLAAKLKAACPNGIDVYFENVGGEVFEAVFPLLNAFARIPVCGLIAQYNAFETPPTPKWATALMRHVLTKRLTIRGFIVSDFAGRRQEFLREMSGWVRDGKVKYREHVTDGLENAPEAFMGLLKGANFGKQLVRVGPERA
>NC_005296.1|WP_011157755.1|2475577_2477074_+|IMP-dehydrogenase
MASVSASPQFIEALTFDDVLLKPGLSDVLPSEVDIRSRITRAIPLNIPIIASAMDTVTEARMAIAMAQAGGLGVIHRNFDPEGQAAQVRQVKKFESGMVVNPLTISPDAKLADALALMNQYGFSGIPVVTGAQGHGPGKLVGILTNRDVRFATDPAQKVSELMTHENLVTVREGVSQGEAKKLLHQHRIEKLLVVDDQYRCVGLITVKDMEKAVAHPLASKDAQGRLRVAAATTVGEGGYERTERLIEAGVDVVVVDTAHGHSARVLDAVTRIKRISNQVQVIAGNIATRDGAQALIDSGADAVKVGIGPGSICTTRIVAGVGVPQLTAIMDAVQACKKADVPVIADGGIKYSGDLAKALAAGADIAMVGSLLAGTDETPGEVFLWQGRSYKAYRGMGSVGAMARGSADRYFQQDIKDTLKLVPEGIEGQVPYKGPVGNVVHQLAGGLRAAMGYVGAKDLGEFHTKAEFVRITGAGLRESHVHDVTITRESPNYPGGV
>NC_005296.1|WP_042441019.1|2487848_2489702_+|type-II-toxin-antitoxin-system-HipA-family-toxin
MALHLVGETIDAKRAHQRAQAGELIQLVRGVYVDDQGDIEATILGHAVRIAHYLYPNAYLSSASAALLAPTPDGRLFISGRRNQRTRLRTLEIIQNEAPKHPSTAIAVIGDDLGELRVDASSPRQRFLEAFRLRSEHASAVTADMRAQMAARLVEEHGTPQAAADAVWVLARENEWYREGEGAERFLLAQPGVAKAPVNKAALDLLVAWHGEPLGRLTHDGFEWRWKPGRRAGPALVRETTPGKLPAFIESLLPEGWLAQVLHERDEREALRRGRRYMSNIVIVEGREELAALPADILTTTLAGYIDTGRFTGRYAGPARGEIEETFEQNLARIFARAETPRLSGVQIKAPMSLMPDGALVPAIDQPFTHILKPAGTAGFETLPVVEWLCLELGRSAGFDVPDAALLEMPDGMSPALVVERFDIRRGPADQRRLAMEDFCSILDLPASAKYDGTIERMARGLRPLSTDPASDLDILFRRAVFAWLIVDGDMHLKNLAVLKVAEVDAKAFTSVRFAPLYDAVTTRVFPGLGGDRMALKLNGKDDRLTRQDFLALARTIGVSAGDAETAIADLTARVADRAQGLQLPAFAADAAAAKTAQEKVIALVGERCKALAVEGD
>NC_005296.1|WP_011157764.1|2489713_2492842_-|DEAD/DEAH-box-helicase
MTDNRFEAEAALAPLKAFQRRTVDYVFDRLYGDQDPVRQFLVADEVGLGKTMVARGVIARTIEKLWDSTDRIDILYICSNQAIAAQNINRLNVLGRRELALPTRMTLIPLQVRGDQGLDANKVNFISLTPGTTFDLRSTTGVTQERALLLRMLEDRVSRPRGLHNLLQVSAGVDGWNTAVRELSLDGVDQRIIDRFRRDVEKDAELFTELEAVCDLFPRRREAYPYELNQRRNALVGRLRGKLSHACIDALKPDLIIMDEFQRFRDLLHGETPAADLARELFDYSDGKGHAARTLLLSATPYRMLTLSGDEPDDGEHYRDFLETLSFLYGRTNGPDVAKALEREMREFRGFLHALPGARNEAIGARHVVEDRLRKVMARTERVASTIERDSMVSEPPMAITILPSDLRQAAAVSDVARALDAPEITEYWKSAPYLLNFMRDYALKRLLKDQLDKPAPNLCAALERARPAMLDRDRLDAYEPLEPANGRMRGVMDDVFGDGLDQHLWIPPSLPYYGPERSGPPLTKALIFSSWSMVPDAIASILSYEAERRMGVGASGQRYFGHVRPRPIQFRQNQGRLVAMRAMHLVYPSPTLARLADPLAIFGASNETLSVEGMRKAVADRLRESVAALAERSGDTADGRDWEWAAPAVIDAMAKASSVAWVNSPYGFALLGNEEGFKEHVAELRTVTTERTFGPVPDTLIDLLVDVALGSPAVCALRALHRIAPDLAWDDHRLLKAANQISWGFRTLFNQHDAVALLRKDDDDRYWRQVLTYGVEHNLQAVLDEYVHYLLDAEGLGAKPAVDRIAGISRAISEALAIRPSQIDVEDPTVDGKKLVINKFQMRGRFAMRLADYKDEEGGAARLSSVRDAFNSPFRPFALATTSVGQEGLDFHPYCYRLYHWNLPGNPVDLEQREGRVHRFKGHAIRLNLAHRQVDVVRGRERDHDDPWQVMFDAARAETENDSDLIPYWIYEGPVKVERRVPMLPFSREVRRLEWLKRSLTVYRLAFGQPRQEDLLEYLHSLMGTAMAAEDLADLQIRLQP
>NC_005296.1|WP_011157765.1|2492831_2494688_-|phospholipase-D-family-protein
MLNRTTLDPETRVLYGDSLQPPPGYVFDAAIATTFSLDFETALAAPVSLALFAAENRDDILTHPLALLEGAERIAGRLVIYADAGHLHAQSRPHSRLCSLLERIIVEVAAPREGAFHPKLWALRYRPTRAEDPTLLRLLVLSRNLTRDRSWDISLRLDGELTRRPDANNRPLFDLLSRLPDLAVAGISDDARTLTAEVAEDIRRARWTVPDRFDEVSFAVNGFGGKIWQPTSCARLGVISPFCDTSALNLLSGLPTAEKPVIISRPDQLACVDSATLDAFERVSVLDEMAATEDGEEVSTSALQGLHAKAFIAETGWDTILTIGSGNATRPALLSGNNVELFASLRGKRSKVGSVEQIMGEKGFGRLTRTFVASELEPIDPATIAAEARLDDARRALCRGGLRLRCERIESIDGDAHPWRVWLIPTEPLPLVGIASLQVWPITRGDGHASDVLDALRAGTAVDLGAMPIVDLTRFLAFRLTADGAQVSALFSTSLVMEGLPPERHAAILRWVIDSRDAFFRYLRLLLSELGDPFGAALAAQEGSGSMAWASAADDAPLLEDMVRALCRGGERLHAIERLMTRLEAGNDTGADPIPSDFRTLWDAFRIALQDQGLSHDG
>NC_005296.1|WP_011157766.1|2494677_2495862_-|hypothetical-protein
MSSLAWIDFDEAERQRAQRIMALFQERETRDELGLGGIRDSIADHLFPGTSTIQTRLRYMLFIPWLFQMLEGSSAGADQLASEARALENRLANALKAGGESNGVIGRDAGADLQRLPSSVYWAGLGTWGIRLFPGSTDNLFSSMRHLQRARPRVRESEDSASEAQALQIWTPTLPARPTDLLDHTQFKLSLDEAQFIIDRLIAHQPHSLLAFLARSGSSQAECDNIWEHPHLADFPDDARTLVGHGAIFSSVMHGASLLYNLLLSRLRDRAEWIEKYEVRFAEWQSSLDMAGIRAWSLDAFWAAIDHPAHSIRPAAKRFVAEWLGLLTAGNVLDGALTPAARLVQDRERRLKTSQSRFANRAVRDRWTGASGVEPLTFRWAQAKSHLRDLASAE
>NC_005296.1|WP_011157767.1|2495914_2499256_-|DEAD/DEAH-box-helicase-family-protein
MLTRATAKAPEQDDLFSEEVTLLFPALLALEGRLLGSAVRQQAVPSALTPCRLKPFTVRRVSGFETNLKSGETLKIISAKTAASLDADLVLLVPGATTAQSIREALERGEGRWLHPKPIDPAALGAQAMLQRLTGVTASWEDAFHLREGRAATDDKPLYPGLRRPQIGALHAALAHATRSTDPATIVMPTGTGKTETMLALNARQGFDRLLVVVPTDALREQIAAKFETFGVLKAQSCLDVSALFPVVTRLTRIPTSIAEVDQIFDSANVIVTTMHIAGRAEPPVQEHMATRASALFIDEAHHIGARTWASFRGLFAERTPPIPVVQFTATPFREDGRRVDGEFIYTYPLKKAQQEGYFKPIRFEAVFGLDQLDADQAIIDKLGDVLAADLDAGLNHLAMARCSTIERAKHLHRLYTLAYPDYRPVIVHSQQSLKERRENLAALRRFDSRIIVCVDMLGEGFDLPELKIAALHDHHKSVAVTIQFVGRFTRQDPRLGDATVIANTGVDDVDRSLAKLYAEDADWNALVEALSSAKIERQVRRAEMFKGFSGDLSDIPLQTLEPKMNAVVYRTACDAWDPFQAEELYDAGIYLGMKLNAHKRVAIFVTRAEEQARWTTAQQAVNVTWDLHMLHWDQASGLLYISSSAKGPFDRLAKAVCGETARRVEGEEVFRSLHGFKRLILRNLGLTHHQGRGVRYSMYMGVDVADGLDSAKSQSRIKNNIFATGFLDGMPASRGCSAKGKFWSSAKVRDLTDWVDWCQDVGRTVNDPSITTDGVFKSAMRPCQINERPAVPPVAIHWPESLIMQIEERIEISFGDQPVSFTECDIELLDNARTGPLRFAVRSDDHSAEFEIVFSDGGARYPQRSGPKATIKIGSKIQSLSESFADDSPQIDFGDGSLLIYSHLYSLPEGETVEPYPVAKIEAWDWSKANIRVESQGTAKRTDSVQRTVIEALLTDPDPYDVIFDDDGKGEIADVVALRITDSVVSATLFHCKYSGADTPGARLSDLYEVCGQAQKSARWRDRPNRMLQHMLKREQKRRDRGLSSRIETGSAAAIKKLKAGWQDYRFEYDVRIVQPGLSRKAIGEEGLHLLAGVETYLLETRGMRLRVIGSD
>NC_005296.1|WP_011157768.1|2499275_2502677_-|UvrD-helicase-domain-containing-protein
MTAATNALRDDAARRTAIGVHDRSILVEAGAGSGKTAVMAGRIAAMLAEGIAPKSIAAVTFTELAASELLIRVRDFVADLAAGTIPTELRIAFPDGLSPNHSANLAAAASVIDEITCSTIHGFCQRLIKPYPVEADIDPGASVMDRNQADLAFIEIVETWLREQLSGGEGGIIAEMVLHNPGGTVGLIHKIVANLRKRRTVSAPPVSGLAPHLAAFHHAVDGLMEFIRTAPAVEEETAMLAERFAGMAAGLDSGPVIETPVGLVRLLVTQPHPDLCTKTGSFLAYKKKGKWVEAAKREGLAKTEGERLNIAADAHYAACCQAWQDLVQNVASRVLCDLIAQVQPVLARFRDYKRSAAQLDFDDLIFAARDLLRDHDDVRRSLATRFAHVLVDEFQDTDPLQTEIFWRLCGEPPAGVASADWSAFTIRPGALFLVGDPKQAIYRFRGADVSAYVRARDAYLAQDPESVLAISTNFRSCAPILTYVNDRFEALLSSEGQPGFTALDPFHADRGEALCVAALDVAVADENGKASAEQQRDGEADAIAQMCARLIGGEMILDRRSGASRPCRPGDIALLAPTGSDLWRYEEALERHGIPVATQAGKGLFRRQEIQDLIALTRVLADRRDTLALGALLRGPLVGLTEEELLDIIWALPRAEDDPERLPRLDLGVELEHIAHPLARSTIETLQALYRQTNSTTPHDLLSQAIDALRVRPILLERHRGQAERALANVDLYLSLTTSFAVRGLRAFAETMTAAWTDEARAVEGRPDAQEEAVALYTMHAAKGLEWPIVVPINTMTGIMAPESAVTDRDSDTFYCPVFGVKPVGYDAARDAEKAELDRERIRLWYVAATRARELLVLPRLDAAQSKSAWISLLDLSLAELPALDLSHLPPELDLAAGGEANDQTRDDFAAEAASIVARQRRLIWLAPSRDESADGPVLTPEAAEIWAASEAGQPDDEAVRPNVQGGRERGLILHKLLEEVLTGETPDDAGALSERARALIGEIGRPVMADPSQGLSPDELAGCVVRTLALPEIAELRPTLVPELAVYAAVDVDGVEQATVGIADATSFDIAGKPTVVIDWKSDVQPTAETLNHYRAQVRAYLDMTGTDRGLIVLVTTGQVIAVTPTTAPLAA
>NC_005296.1|WP_042441021.1|2502676_2505289_-|PD-(D/E)XK-nuclease-family-protein
MRELRLDAARQRRHGVQIMSFEQLAVRLAGGFARPIDDECLRTAIQAVLPDTTLGELESIKLLPGMVDAAADTLHKAWRAGIDLAARAGDHPRLDSIARLEAAVLAQLPPGMMRPTDLVARALERVAHAHAVLGPLEIVGITELSPCWRPLLQELTAHTSVSWTAGPRPTPPWLDAFDVTINRADPTAPAISTVSAATAYHEAIEAIRWARGLMASGEAEPADIAIAAASTGDYDDHLLALRADANLDLHFVHGIKVTTTRDGQAAAALADLLIRGFSQTRMRRLAALCGSETGPFAGLPQGWLRVLPTDAPLASPASWHRLLDRLTADDWPDATDHTPTLRGIIDLLAKGHPTAAEIGAAFLSGRALAIWRKALLAGPSGSLDATLDSLKQDDGLEACVSVAWMPASALAASPRRFVRLIGMNSSRWPRGISEDRLISDHIIPTAELDPLPVGAADRRDFETILATTSGQIVMSRARRDSEGRLLGRSALLGPASEEIYIRRNAVPAHAFSETDRLMARPDEFARDSQAISATTAWRNWHRKEITPHDGLVRADHPLLQAILGRTQSASSLRLLLRSPLGFVWRYGMRLRTPESGADPLVLDALAMGDLVHMTLDLALATLEKGGGLAAADEAQIAGAVQDAAARIAVVWESERAVPPALIWRRTLDDARILTTRALTYGDEHLPDARSFGEVAFGGATPKADTASPWDSQTPVEIPATGFRIAGYIDRLDIAGDGKRALVRDYKTGRPPKDDISLDGGRELQRCLYAFAVKALLGDDVSVSASLLFPRDQVDFQLGDPEATLTEITGYLQAARANLQSGQALIGPDTGGAYDDLAFALPANAGATYCKRKLPAATEAFGDAALVWEAQ
>NC_005296.1|WP_162843685.1|2505356_2505500_-|hypothetical-protein
MAKTPSKNEVTSKKAASAASQVLRDPKSSAAAKSAAASALTQRPNKK
>NC_005296.1|WP_011157770.1|2505625_2506510_+|WYL-domain-containing-protein
MAESLTTLKWGVERRLEFIEFRLFWEGGVNRSDIIEMFDVSVPQASKDLTLYQERAPNNALYDKSAKRYVASEHFEPHFLKPDPDGYLSRLRSVAEGLIDLSESWITQVPDTDIALTPRRDIDASVLRTVLSAVRDHRSVDIHYQSMSKDRPDPIWRRITPHAFGYDGFRWHVRGYCHVTDKFKDFLLPRVLGIGSLDEPGAPAEHDALWQERFGVEIGPHPDLTTSQKAVVAKDYGMEKGSAVLTVRYAMLFYVLKRLGLLGDAAKLPARSQHIVVVNQAETEAALEKADFAV
>NC_005296.1|WP_011157771.1|2506543_2510062_+|DUF3883-domain-containing-protein
MARLEEIRNGASVRGIASPQAAQILSVDWIGDQAINVVYRDLNGAVAEAVLYRDDEYRLEVEVNGRPWSFDGDGALLRLVTEANRIKLAHFFDPYLAIHTSLVDPLPHQISAVYGEMLPRQPLRFLLADDPGAGKTIMAGLLIKELIARSDLERCLVVAPGSLVEQWQDELGQKFNLEFDILTRDMIETSRSGNPFEDRNRLIVRLDVLARNEELQEKLASAREWDLIICDEAHRMSATYFGGDVKYTKRYQVGQKLGEACRHLLLMSATPHNGKEEDFQLFMALLDGDRFEGRFRDGVHYADTADMMRRLTKEELLRFDGRPLFPERRAYTVKYQLSELEAALYTAVTEYVRTEMNRVQRFAEGDGKKRNNVGFALQILQRRLASSPAAIYQSLKRRRERLENELGEARLAAKGRRAGFAAPDVNADILKNIEEYGQDEIDDLEDLIATGATTAETVEQLALEVETLKGLETMALGVLRSGLDAKWTQLNRILDDDLMVDADGNRRKLIIFTEPKDTLHYLVDKVRARLGNPDAVDVIHGGVSREERRKVIERFMQDRDMLVLIANDAAGEGVNLQRGHLMVNYDLPWNPNKIEQRFGRIHRIGQTEVCHLWNLVAADTREGEVYARLLEKLEAAREALGGRVYDVLGELFEGVALKDLLFQAIQYGEQEDVKARLFRQVDGAVDQGHLLELLQRRALTNDTMPEAKVEELRLEMERAEAQRLQPHHVQSFFVEAFQHLGGKMKRREEGRWEITHVPVRIRERDRQIGTGAPIQKKYERICFEKGRINQQPVATFVCPGHPLLEAVISIVREQYEQIMRQGAILVDDLDAGTDLSAVFLLEHSIQDGLATSAGKPHVVSQKLQFASINKAGEAVNAGIAPHLNLRPATPEEIASVQDVLHEDWLTTELEKTAVRFATVELAQAHVAEIKARRLPEIEKVEREVRARLKKEINYWDSRAFELKEEEKAGKKTRLSWQNAQRRAEDLAERQKRRMDQLEQERFISSQPPRVRGGMVVVPRGLLDARGIPGAAPAEGAPPPFSADADARRVIELAAMDAVIATERALGNVPSDVSAQKIGYDIASYDPRTKHLRFIEVKGRVHGADTVMITRQEVITSLHEPDKYILAIVQVEDGTARDPRYVHGALSDHEPSFEHTAIQFHLARLLERAEAPR

Crispr_ID: NC_005296_2

• CRISPR_ID: NC_005296_2
• CRISPR_location: 4073755-4073853
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_005296_2

Consensus_repeat	Method
GCCGTAGCGCGGATCGTCCGGCGA	CRISPRCasFinder

spacers of NC_005296_2

>2.1|4073779|51|NC_005296|CRISPRCasFinder
CATCACCGGGCCTTGCGGGGCAGCATTGGAATAGACCGGCGCGGCTGAACC

CRISPR arrays and Neighbor proteins around NC_005296_2

CRISPR arrays

The CRISPR arrays of NC_005296_2

>merge|NC_005296|2|4073755-4073853|CRISPRCasFinder
GCCGTAGCGCGGATCGTCCGGCGACATCACCGGGCCTTGCGGGGCAGCATTGGAATAGACCGGCGCGGCTGAACCGCCGTAGCGCGGATCGCCCGGCGA

>NC_005296|2|2|4073755-4073853|CRISPRCasFinder
GCCGTAGCGCGGATCGTCCGGCGA	CATCACCGGGCCTTGCGGGGCAGCATTGGAATAGACCGGCGCGGCTGAACC
GCCGTAGCGCGGATCGCCCGGCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_005296.1|WP_011159160.1|4083933_4084926_+|oxidoreductase	unknown	unknown	gnl|CDD|99782
NC_005296.1|WP_011159156.1|4080471_4080726_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl|CDD|225170
NC_005296.1|WP_158255410.1|4069541_4069688_+|hypothetical-protein	unknown	unknown	unknown
NC_005296.1|WP_011159147.1|4070228_4070630_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|224404
NC_005296.1|WP_119846021.1|4078409_4080302_+|diguanylate-cyclase	unknown	unknown	gnl|CDD|143635
NC_005296.1|WP_011159157.1|4080840_4081683_+|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NC_005296.1|WP_042441217.1|4066588_4067833_-|lytic-murein-transglycosylase	unknown	unknown	gnl|CDD|274067
NC_005296.1|WP_011159152.1|4075486_4076347_-|3-mercaptopyruvate-sulfurtransferase	unknown	unknown	gnl|CDD|225450
NC_005296.1|WP_011159158.1|4082100_4083144_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl|CDD|176887
NC_005296.1|WP_011159154.1|4077025_4078201_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|226346
NC_005296.1|WP_011159153.1|4076463_4076880_-|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238724
NC_005296.1|WP_042441218.1|4074481_4075474_+|hypothetical-protein	unknown	unknown	gnl|CDD|236138
NC_005296.1|WP_011159149.1|4072526_4072727_+|hypothetical-protein	unknown	unknown	unknown
NC_005296.1|WP_011159141.1|4066227_4066512_+|hypothetical-protein	unknown	unknown	unknown
NC_005296.1|WP_011159146.1|4069977_4070232_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|198034
NC_005296.1|WP_011159144.1|4068597_4069368_-|trans-aconitate-2-methyltransferase	unknown	unknown	gnl|CDD|234970
NC_005296.1|WP_011159159.1|4083147_4083903_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NC_005296.1|WP_011159148.1|4070636_4072286_-|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NC_005296.1|WP_011159143.1|4067832_4068423_-|TIGR00645-family-protein	unknown	unknown	gnl|CDD|179964
NC_005296.1|WP_011159140.1|4065647_4066007_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_005296.1|WP_011159160.1|4083933_4084926_+|oxidoreductase	gnl|CDD|99782	cd06185, PDR_like, Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur [2Fe-2S] cluster domain. Although structurally homologous to FNR, PDR binds FMN rather than FAD in it's FNR-like domain. Electron transfer between pyrimidines and iron-sulfur clusters (Rieske center [2Fe-2S]) or heme groups is mediated by flavins in respiration, photosynthesis, and oxygenase systems. Type I dioxygenase systems, including the hydroxylate phthalate system, have 2 components, a monomeric reductase consisting of a flavin and a 2Fe-2S center and a multimeric oxygenase. In contrast to other Rieske dioxygenases the ferredoxin like domain is C-, not N-terminal.	6.19714e-72
NC_005296.1|WP_011159156.1|4080471_4080726_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl|CDD|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	8.17717e-08
NC_005296.1|WP_119846021.1|4078409_4080302_+|diguanylate-cyclase	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	8.01665e-47
NC_005296.1|WP_011159147.1|4070228_4070630_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|224404	COG1487, VapC, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	3.97185e-13
NC_005296.1|WP_011159157.1|4080840_4081683_+|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	2.98233e-47
NC_005296.1|WP_042441217.1|4066588_4067833_-|lytic-murein-transglycosylase	gnl|CDD|274067	TIGR02283, Membrane-bound_lytic_murein_transglycosylase_B, lytic murein transglycosylase. Members of this family are closely related to the MltB family lytic murein transglycosylases described by TIGR02282 and are likewise all proteobacterial, although that family and this one form clearly distinct clades. Several species have one member of each family. Many members of this family (unlike the MltB family) contain an additional C-terminal domain, a putative peptidoglycan binding domain (pfam01471), not included in region described by this model. Many sequences appear to contain N-terminal lipoprotein attachment sites, as does E. coli MltB in TIGR02282. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	7.17341e-132
NC_005296.1|WP_011159152.1|4075486_4076347_-|3-mercaptopyruvate-sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.82908e-107
NC_005296.1|WP_011159158.1|4082100_4083144_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl|CDD|176887	cd08878, RHO_alpha_C_DMO-like, C-terminal catalytic domain of the oxygenase alpha subunit of dicamba O-demethylase and related aromatic ring hydroxylating dioxygenases. C-terminal catalytic domain of the oxygenase alpha subunit of Stenotrophomonas maltophilia dicamba O-demethylase (DMO) and related Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs, also known as aromatic ring hydroxylating dioxygenases). RHOs utilize non-heme Fe(II) to catalyze the addition of hydroxyl groups to the aromatic ring, an initial step in the oxidative degradation of aromatic compounds. RHOs are composed of either two or three protein components, and are comprised of an electron transport chain (ETC) and an oxygenase. The ETC transfers reducing equivalents from the electron donor to the oxygenase component, which in turn transfers electrons to the oxygen molecules. The oxygenase components are oligomers, either (alpha)n or (alpha)n(beta)n. The alpha subunits are the catalytic components and have an N-terminal domain, which binds a Rieske-like 2Fe-2S cluster, and the C-terminal catalytic domain which binds the non-heme Fe(II). The Fe(II) is co-ordinated by conserved His and Asp residues. Oxygenases belonging to this subgroup include the alpha subunits of carbazole 1,9a-dioxygenase, phthalate dioxygenase, vanillate O-demethylase, Pseudomonas putida 2-oxoquinoline 8-monooxygenase, and Comamonas testosteroni T-2 p-toluenesulfonate dioxygenase. It also includes the C-terminal domain of the lignin biphenyl-specific O-demethylase (LigX) of the 5,5'-dehydrodivanillic acid O- demethylation system of Sphingomonas paucimobilis SYK-6. This subfamily belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket.	6.43925e-60
NC_005296.1|WP_011159153.1|4076463_4076880_-|rhodanese-like-domain-containing-protein	gnl|CDD|238724	cd01447, Polysulfide_ST, Polysulfide-sulfurtransferase - Rhodanese Homology Domain. This domain is believed to serve as a polysulfide binding and transferase domain in anaerobic gram-negative bacteria, functioning in oxidative phosphorylation with polysulfide-sulfur as a terminal electron acceptor. The active site contains the same conserved cysteine that is the catalytic residue in other Rhodanese Homology Domain proteins.	1.76175e-58
NC_005296.1|WP_042441218.1|4074481_4075474_+|hypothetical-protein	gnl|CDD|236138	PRK07994, PRK07994, DNA polymerase III subunits gamma and tau; Validated.	1.62797e-11
NC_005296.1|WP_011159154.1|4077025_4078201_-|VWA-domain-containing-protein	gnl|CDD|226346	COG3825, COG3825, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_005296.1|WP_011159146.1|4069977_4070232_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	1.62014e-09
NC_005296.1|WP_011159144.1|4068597_4069368_-|trans-aconitate-2-methyltransferase	gnl|CDD|234970	PRK01683, PRK01683, trans-aconitate 2-methyltransferase; Provisional.	1.88228e-177
NC_005296.1|WP_011159159.1|4083147_4083903_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.7641e-34
NC_005296.1|WP_011159148.1|4070636_4072286_-|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NC_005296.1|WP_011159143.1|4067832_4068423_-|TIGR00645-family-protein	gnl|CDD|179964	PRK05208, PRK05208, hypothetical protein; Provisional.	2.68037e-96

Protein sequences

>NC_005296.1|WP_011159149.1|4072526_4072727_+|hypothetical-protein
MASLTTTTEVHHDEQAGPDTSLLSEIRLFWRQFFVQAFNPYRPEMYYMRGPGPAWHAKHGHKPTRH
>NC_005296.1|WP_011159148.1|4070636_4072286_-|energy-dependent-translational-throttle-protein-EttA
MARQFVYFMQGLTKAYPTRKVLDNVHLSFYPDAKIGVLGVNGAGKSTLLKIMAGIDKEYTGEAWVAEGARVGYLEQEPQLDPALTVRENVMLGVAKQKAILDRYNELAMNYSEETADEMTALQDQIESAGLWDLDSKVDQAMDALRCPPDDADVTKLSGGERRRVALCKLLLDQPDLLLLDEPTNHLDAESVSWLESHLRNYPGAILIVTHDRYFLDNVTSWILELDRGRGIPYEGNYSSWLVQKQKRLLQEGREDAAHQKTLEREQEWIASSPKARQAKSKARYQRYEELLAKASEKQTQTAQIIIPVAERLGNNVVDFEHLTKGFGDKLLIDDLTFKLPPGGIVGVIGPNGAGKTTLFRMITGQEKPDQGTITVGETVHLGYVDQSRDSLDAKKTVWEEISGGNELILLGKKEVNSRGYCSAFNFKGGDQQKKVGSLSGGERNRVHLAKMLKSGANVLLLDEPTNDLDVDTLRALEEALEDFAGCAVIISHDRWFLDRIATHILAFEDDSHVEWFEGNFQDYEKDKMRRLGQDAIIPHRAKYKKLTR
>NC_005296.1|WP_011159147.1|4070228_4070630_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MTLVDTNVLIDVLSLDQTWQVWSATALWQQSLHGSLLINEIVYAELASRYASQQALDEVIDHLNLEVEWIPRPALYIAGRVFSDYRRAGGVRTSVLADFFIGAHAAAVKIPILTRDARRYRTYFPDVALITPD
>NC_005296.1|WP_011159146.1|4069977_4070232_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MATTITSKGQVTLPKKVRDAAGIKPGDKVEVRSTASGGIYIGKSGSEADYLKKLQAIAKRYPIHGGTDEIMHELRGDVADDYER
>NC_005296.1|WP_158255410.1|4069541_4069688_+|hypothetical-protein
MTIPTEARPSEFASQILGRLPSDLDPLPIEVLKQIKVAGNKRDLSYRR
>NC_005296.1|WP_011159144.1|4068597_4069368_-|trans-aconitate-2-methyltransferase
MADWNAEQYLKFEDERTRPARDLLAQVPTTAPRKVADIGCGPGNSTALLVERWPEASVIGVDTSADMLRQARERLPQHKFIEANVAHWAPPAGTDVLFANAVFQWVPDHLKQLRRLLSGLDSGGVLAVQMPDNLDEPSHIMMREVALQEPWRHQLSKAAELRDTLPKPSVYYDALKPLCSRLEIWHTVYNHALDGPEAIVEWVKGTGLRPFIDPLELPERKTYLAAYTARIAAAYPAQADGQVLLRFPRIFIVAVK
>NC_005296.1|WP_011159143.1|4067832_4068423_-|TIGR00645-family-protein
MSMTPETPLPPKGLGLRPIPMLIFGSRWLQLPLYVGLIVAQGIYVVLFLKELWHLFQHSFDFSEQQIMLAVLGLIDVVMISNLLVMVIVGGYETFVSRLNLRGHPDEPEWLSHVNASVLKIKLAMAIIGISSIHLLRTFIEAGNLGAAGKVGGYTETGVMWQTIIHTVFILSAIGIAWVDRISNLATEEAKAHAGH
>NC_005296.1|WP_042441217.1|4066588_4067833_-|lytic-murein-transglycosylase
MRLTHAVALAVGVAVAASVAFGASVARAADPGFTRFVAELWPEAREAGVSRATFDAVTAGLEPDYKLPDLILPGRPKTGAPRQAEFVQVPADYLKEARIESLAAHGRTLMQRYRPTLDAIERKFGVPATVVLAIWGRETDYGRYKLPYDAVRVMATQAYVGRRKDQYRTEFILAMKIIGEGAVTRQEMRSSWAGATGLTQFLPSEYYKHGVDFDGDGRVDIWHSVPDALASAAQQLVNKGWQSGLRWAYEVKAPTRADCTEGVPEVTKPIGQWLREGFALARPDRLSAAEREQLTSLLQPEGIYGPAFLTTKNYFVIKEYNFSDLYVLFVGHLADRMTDPRPFATPWSATKQLRTTDVEAMQRGLERLGIYRDKIDGKAGMLTRAALGAYQKRAGLQVDCWPSEAVLRSIQAAR
>NC_005296.1|WP_011159141.1|4066227_4066512_+|hypothetical-protein
MKKTVTVLLAAATIAGSLVGVAPAAKADGGRIAAGVAGGLIGGALLGGAIAASRPAYAAPAPVYVEEPDCHWVRERFWDDYAGVWRSRRVRVCD
>NC_005296.1|WP_011159140.1|4065647_4066007_+|hypothetical-protein
MRKSMMALAAAAALAVTAVGSTAPAQAHDGFGAGIAAGLIGGALIGGALSSPYYGPGGYYYGGGYGYGPRYYSYGPRYYGYAPAPAYVASPGYYGGCYWQRQRFWDGYGWRIRRIRVCD
>NC_005296.1|WP_042441218.1|4074481_4075474_+|hypothetical-protein
MLPGFRFLFAAMTLAVSLLVFGLGAAALLRAAHEQFVNVHTVRPPAITLLARAPEAPTPSLSMLRVDSPAPPAPAAEPPAAAANQSPNTTDPVAADVAALGNGEGATPEAKAAEPAQTAALQPSAAETPAAAQAAQPPQAEQTLAAPEPASQASSPPPAAAPEAVAPAALPAATAATSADAPKPDDKPQAGAEKAVTPAAPTQTAATETAAPATPAPPVATAPSAEALPEVAPLSGPIPTPRRDPRDRTKTATNTPAAPSAATPAAPAADTPTTDVTGSIGETLPPPDATPLPVARPKPVVRRPLKKRRQVARRRTPRAEQPQSGSGVGL
>NC_005296.1|WP_011159152.1|4075486_4076347_-|3-mercaptopyruvate-sulfurtransferase
MTAHTDPLVSTDWLAERLGDPSVKIIDASFKMPGVLPLPADDYLAAHIPGAVFFDVDAVSDHASSLPHMYPSADQFARDVEALGISSGDTVVAYDAGGWVAAPRAWWMFLSFGHANIRILDGGLKKWVAEGLPTEAGKPTIAPGRFSAKLDPSFIRSRDQLVANLDSGAEQVIDARAAPRFEGSVAEPRPGLRAGHIPGSRNLPYNELFDAATGTMKPLAELRQAFERAGLDLGRPVVTSCGSGVSAAVLTLALYRLGVRGSALYDGSWSEWGLQDGPPVATGPAA
>NC_005296.1|WP_011159153.1|4076463_4076880_-|rhodanese-like-domain-containing-protein
MPQTITRGIKAMLDEANSSIETLTTADAIALHKSGASDVVIVDIRDPREIERDGKIPGSFSCTRGMLEFWIDPQSPYAKPIFQEDKKFVFYCAGGLRSALAAKTAQDMGLKPVAHIEGGFGAWRDAGGPIEAWAPKKK
>NC_005296.1|WP_011159154.1|4077025_4078201_-|VWA-domain-containing-protein
MFLQFFTSLRDAQVPVTLREYLTLMEALDADLADQSVENFYYLSRAALVKDERNLDKFDRVFGATFKGLENLLDAMDKAEIPAEWLKKLAEKYLSEEEKKQIEAMGWDKLMETLKKRLEEQKKRHQGGNKWIGTAGTSPFGAEGYNPEGVRIGQEKSRHQRAVKVWDKREFKDLDGNVELGIRNIKVALRRLRKFARTGAPDELDLDTTIRETANHGYLDVHMRPERRNAVKVLVFFDIGGSMDSHVAQVEELFSAAKSEFKHMEYFYFHNCLYEGVWKQNKRRFTDRTPTWDVLHKFPHDYKVVFVGDASMSPYEIMVPGGSVEHVNEEAGHVWLERVLRTYPHAVWLNPVAQRHWDYSESTTIIRRLFSERMYPITIEGLEGAMRELVR
>NC_005296.1|WP_119846021.1|4078409_4080302_+|diguanylate-cyclase
MSTATLVVAMFVVALGACVLGLVVWKGYDSHKIALAQSETEMRNLSHSLAEHATHTFQGADVVLDDIVSFMKWRPHPSPVFNERLRALADNLPQLSDVAILDADGQLTYASVKPVPALDNSDRSYFRYHRANDDHTLLITGPIQSRTSGVWVFVVSRRLETTDGKFFGVVVATIESEYFSTFYKTFDLGPGGSISLLHSDGRLLIQWPSLQTGRDMANMVLFQKALPRSPDGYYLTVSPFDGLTKYLAYRRVSRYPLVVTVARTEDSVLSGWREAVRSDAVVATAMLACVVLLAAGLAAQLRTRQEVQNLLRERDAHYRLIDTNMGDVIVLTDEVGILRFVSMSVETVLGLKADRLVGRLWTVLVHPDDVPFVEAVGAGLPDSPAGLCVEFRMRCPEGRLVWLEANFAYTRNEDGPTDCVVSTLRDITRRKAMEKEVEALNARLAELARTDGLTGLPNRRSLDGFVARVITSSPTLSVLMIDVDDFKGFNDHFGHQGGDDALRQLGHLFGGLVASVHGFAARYGGEEFTIVLPGADAVAAVDFAESLQAAVRTLAIRNPASARGYLTVSIGIACGTAPCDSTVLLRDADIALYEAKRRGRDCCVTAATAFVDDAAPLQPEQPSASADATS
>NC_005296.1|WP_011159156.1|4080471_4080726_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGIDSILVWLLVGAIAGWLAGLIVRGGGFGLVGNVVIGIVGAVVAGWLLPFLGVNLGVGIFRAIINSAIGAVIVLVLLAMIRRA
>NC_005296.1|WP_011159157.1|4080840_4081683_+|MoxR-family-ATPase
MKFTGTKDYVATDDLKVAVNAAIVLERPLLVKGEPGTGKTVLAEEVAKALNAPLLTWHIKSTTKAQQGLYEYDAVSRLRDSQLGDPRVSDIKNYIKRGKLWEAFTHEGRPVLLIDEIDKADIEFPNDLLLELDRMEFHVYETGETIRADKRPIVVITSNNEKELPDAFLRRCFFHYIKFPDADTMQAIVDVHFPGIKQRLVEEALKIFFEVRDVPGLKKKPSTSELLDWLKLLLNEEMSPEQLRERDPRKLIPPLHGALLKNEQDVHLFERLAFLSRREV
>NC_005296.1|WP_011159158.1|4082100_4083144_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MPAFPLNAWYAAAWDADIKHALFPRTICGKHVVMYRKADGTVAALEDACWHRLVPLSKGRLEGDTVVCGYHGLKFNPQGRCTYMPSQETINPSACVRSYPVVERHRFVWLWMGDPVLADPALVPDMHWNDDPAWAGDGKTIYAKCDWRLVVDNLMDLTHETYVHGSSIGNEAVAEAPFDVTHGDRTVTVTRWMKGIEPPPFWAAQLGKPGLVDRWQIIRFEAPGTVTIDVGVAPAGTRAPEGDRSQGVNGFVLNTMTPETDTTCHYFWAFVRNYRLSEQRLTTEIREGVSGIFREDEIILEAQQRAMLENPDRVFYNLNIDAGAMWSRKLIDRMVAQESAPKLQAAE
>NC_005296.1|WP_011159159.1|4083147_4083903_+|GntR-family-transcriptional-regulator
MNDKAAERSMSQTVRAQLALRDMVLSGQLRAGERISELQAVEITGVSRTPVRMALVRLEDEGLLQAIPSGGFMVKAFSERDILDSIELRGTMEGLAARLAAERGASVRQLEPLKQCLSDIDELVRQDPISVDAFSAYVALNARFHALLNELCGSAPVMRQIDRVAALPFASPSAFVMAQSGLAEAHQILLIAQDHHRAVIDAIENREGARAEAVMREHARLAVRNLRLALRNRTHLDLLPALTLVTQAADK
>NC_005296.1|WP_011159160.1|4083933_4084926_+|oxidoreductase
MRFAEQWTSSTVVSTRNLTSLIREIVLEPDVAVTTCAPGSHINVAVMIDGQADKRSYSLVGPPEQGRLRIAVRLAADSRGGSQAMWALKPGQRIDITHPTSLFEIDWSRQHYALIAGGIGVTPMLGIAAALARRSTELTMHYAVKSRSDAALHDELSSLLGDRLRLHAGDEDARLDLDATFRALPEGAVAVLCGPLRMLEAARHAWHQAGRPASDLCFETFGSSGRLPTSEFRVRIAATGSEIVVPRDRSMLDALNAAGFEVISDCERGECGVCAVDVTAIEGEIDHRDVFFSEHQKHDSGKMCACVSRARGTVTIDTLYRPDQLPGAVA

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_005296_1	1.1|2487791|31|NC_005296|CRISPRCasFinder	2487791-2487821	31	NZ_CP045855	Agrobacterium sp. MA01 plasmid punnamed1, complete sequence	50267-50297	8	0.742

1. spacer 1.1|2487791|31|NC_005296|CRISPRCasFinder matches to NZ_CP045855 (Agrobacterium sp. MA01 plasmid punnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

tcttgcacgcaaagccggatcgtgggattaa	CRISPR spacer
gaccacaagcaaagccggatcgagggattac	Protospacer
  ...** ************** ******* 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2118612 : 2131987	14	Geobacillus_phage(25.0%)	tail,capsid,head,portal,protease	NA
DBSCAN-SWA_2	3219530 : 3226156	8	uncultured_Mediterranean_phage(83.33%)	tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_005296|2118612:2131987|DBSCAN-SWA
GATGTTCGATCGTCTCAAGGCCTTTCTCACCGTCCCGGAAGCCAAGACGTCGCGAACCGCGCAGTTACTTGCGGTGGGATTCGGCGGAGTGGCGCGATTTACCCCGCGGGACTACGCCGGGCTGGCGCGTGAAGGCTACGTACGAAATGCAATCGTGTATCGCTGCGTCAGGCTGGTGGCGGAGAATGCCGCAGCCTGCGTGTTCGGCGTATTCGACGGCGCGCAGGAGAAGGAGGCACATCCGCTCGCGGCTTTGTTAGCGCGCCCCAATCCTCGCCAGGATGGCGCCGCGCTGCTGGAGACGCTGTATGCGCATCTTCTGCTCGCGGGCAATGCCTATATCGAGGCGGTGACGCTCGGTGAGGCCGTGCACGAGCTCTACGCGCTGCGGCCCGATCGCATCAAACTGATCCCGGGCACCGATGGCTGGGCGGAGGCGTATGATTACAGCGTCGCCGGCCGCACCGTGCGGTTCGATCAGCATGCCACTCCGGTTCCGCCGATTCTGCATCTGACGTTTTTCCACCCGCTCGACGATCATTACGGCCTAGCGCCGCTCGAAGCCGCCGCGGTCGCGGTCGACACCCACAACGCGGCGGCGCGCTGGAACAAGGCTCTGCTCGACAATTCCGCGCGGCCTTCGGGCGCGCTGGTGTACGCCGGCCCGGAAGGCGCCGTGCTCAGCGAGAACCAGTTCGAACGGCTGAAACGCGAACTGGAGAACACCTACGAAGGCGCCGCCAATGCCGGTCGGCCGCTGCTGCTCGAAGGCGGGCTGGAATGGAAGGCGATGGCGCTGTCGCCGAAGGACATGGACTTTCTCGAGGCCAAGCACGCCGCCGCACGCGAGATCGCGCTGGCGTTCGGTGTGCCGCCAATGCTGCTCGGCATTCCCGGCGACAACACGTTCTCGAACTATCAGGAAGCCAACCGCAGCTTCGTGCGCCAGACCGTGTTGCCGCTGGCGACGCGCGTCGGCAATGCTCTGGCGCAGTGGCTGTCGCCGCAATTCGGAGATGGCGTGCGCCTGGTGATCGACACCGACCGGATCGACGCGCTGTCACCCGACCGCACCGCGCTGTGGGACCGAGTCACCCGCGCGCCGTTCCTCACCCTGAACGAAAAGCGCGAAGCGGTCGGCTACGCGCCGATCGAAGGCGGCGACCGACTGGGGTGAGCCACTCGGGCCGCGGAGCTTGCCGATGTCCGATCTAATCAAGATGTTTTCCGAGCGCGGTGACCTCGCTCACGTGGCGCTGTTGCTGTGGGCGATCGGGGCCAGTCTCGGGTTGTGGTTTGTACTTCGCGAGTGGGCGGCGGCGGTGCGGCGGTTTGATGATTTCGTCCACGCGCTCGATCTGTTCAACCGCCGCGCGCGGCGCCGGGCGCAGGACGAGGAGTAGGGCGATGCAACGGCTGTCCAGCGTGCTGAGCCGGGTCCGTGCCGAGACCAAGTCGGCGCGCGATCCGCAGGCGATCTTCCGCGAATTCCTGGCGCATCTGTCCGGCGCGCAACACAAGCCGGCGCCGCGGCGCGCTGCGCCCAAGCCGCCGCGCAAGCGGTCGGCCAAGCGCGCGAAGTAACCGCTCGGTAAAACCCGCGAAGTAACCGCCGCGAACCAGCGGCACCCGCCGCGACCGACATCGCTCACCACCACGCTCTCCACCATCGCCATCCCACCTCACTCGTATCTTGCGAGGCCGCACATGCTTGCCCCGTCGCCTGCGCTCGCCCCGTCGCTTTCGCCTGCGCCGCTGCCGGCGCGGCTGTCGCTCGCCGAGGACGGCAGCATCGACGGCTATGCCAGCCTGTTCGGTGAGATCGACCAGGCCCGCGACATGGTGATGCCCGGCGCCTTCACCCAGACGCTGAAGCAGCGCGGCTTGCGCAAGATCCCGATGCTGTTCCAGCACGATCCCGCCGAGCCGGTCGGCGTCTGGCTGGAGCTGGCGGAAGACCTGCGCGGCCTGCGCGCCCGCGGCCGGCTGATCCCGGACGTGGCGCGCGGTCGTGAGCTGCTCGCGCTGCTCCGCGCCGGTGCGATCGACGGGCTGTCGATCGGCTATCGCACCGTGCGCGGCCAGATCGATCCGCGGACGCGGGTGCGGCGGCTGTACCAGGTCGATCTCTGGGAGATCTCGATCGTCACCTTTCCGCTGCTGAGCGGCGCGCGCATCGCCACCGTCAAGCACACGCCGCGGCCCTCGCCGCAGCGCGCCGCGGCGGAGGCGGCGTGGCGCCGCGTCCATGACGCGGCAGCGACCCGTTCCGGCGATGCCGCGGAGGCACCGGCATCGCCGATCCGGCGCGGGAGGATCGCGGCGACGCTGTCCACCCGCGCCGGGCGCAAACAGGCGCTGGCGAGTTTCAGCCGGCGCGGCTGAGGCGCGCGCAGGGCCCGCCGTCGATCCGCGGGGCAAGTAACACCACCCGCTTTGCCTTGCCCCTCACCCCAGCCCTCTCCCCGCAGAAGGGCGGGGAGAGGGGGCCGGCCGCGGCGCGCGGCGACGCGCCCGATCGCAACAAACACTCCATCCCCCACGAAGGACCAGCCGATGACCACGTTCGACCATGCTCCCGAGACCAAGGCCGGCTTTGCCGGCGACGATGCGCAGCAGGTGTTCGATGCCTTGATGCGCGCGTTCGAGGACTACAAGGCCGAGAACGACGCGCGGCTGAAGGCGATCGAGACCGGCAAGGGCGACGTGCTGGCCGAGGAGAAGCTGGCGCGGATCGACGCCGCGCTGGATCATCAGCAGCGCCGGCTCGACGAACTGGCGCTGAAGGCGGCGCGGCCGCAGCTTGCGGCGGAGCGGCCGCAGCCGGCCGCCGATCAGCGCGAGCACAAGAGCGCGTTCGAGGCCTATGTGCGCACCGGCGAGGCCGCCAGCCTGCGCCGGCTGGAGACCAAGGCGCTGTCGGCCGGCTCGGCGCCCGACGGCGGCTATCTGGTGCCGACCGAGCTCGAGCACACGATCAGTTCGCGGCTCGCCGCGATCTCGCCGATCCGCTCGCTGTCGACCGTGCGCGAGATCTCCGGCGGCGTGTACAAGAAACCGTTCGTCACCGCGGGGCCTGCGACCGGCTGGGTCGGCGAGGGCGACGCCCGGCCGCAGACCAATGCGCCGTCGCTGGATGCGCTGTCGTTTCCGGCGATGGAGCTGTACGCGATGCCGGCCGCGACCGCGACGCTGCTCGACGACTCTGCAGTGAATATCGACGACTGGCTGGCCGGCGAGATCGACCAGGCGTTCGCCGAGCAGGAGGGCATCGCCTTCGTGTCCGGCGATGGCGTCAGTAAGCCGAAGGGCTTCCTCGCCGTGCCGACCGCGGCCAACAGCGCCTGGAGCTGGGGCAAGCTCGGCACCATCTCGACCGGCGCCGCCGGCGCGTTCGCCGCCACCGCGCCCGGCGACGTGCTGATCGACGTGATCTACGCGCTGCGGCCGGGCTATCGCCAGAATGCCAGCTTCGTGATGAACCGGCGGACGCAGGCGGCGATCCGCAAGTTCAAGGATTCCTCCGGCGCCTATCTGTGGCAGCCGCCGGTCACCGCCGGCGGCCGCGCCAGCCTCGCCGGTTTCCCGCTCGCGGATGCCGAGGACATGCCGGACATCGCGGCGAATTCGCTGTCGATCGCGTTCGGCGACTTCCGCCGCGGCTATCTGATCGTCGATCGCCAGGGCGTGCGCGTGCTGCGCGATCCGTATTCGTCGAAGCCCTACGTGCTGTTCTACACCACCAAGCGCGTCGGCGGCGGCGTCCAGGATTTCGACGCCATCAAGCTGGTGAAGTTCGCGGCGAGCTGAGGCGCAGCGCCGGTTCTCCCTCTCCCGCGCGCGGGAGAGGGCCGGGGTGAGGGCTGTAGGGTGGGTTAGGCGCGTAGCGCCGTAACCCACCGACCACCTGTATACCGAGTGCCAAAGCATCGCAGTCTCTGTCCTTGAGCGCTCGATCACGAGCGGGACTTGATGTTGGCGAGTAGTCCTGGCAGCGTTCGGAGCTGAACAACAGGTCTGCTCTATCGGCGGTATTTCGAGCGGAGGTCGAGCGCTGATAACCTCGACCGCGAATTCGCCGGCAGTCGAAGCGGATATACGCACAGCCCATGGAGGCGGGCCGCCGCCGGAGGTCGGAGCCATGAGTAAGCTGGATCTGCACCAGATGACGACGCAAGATCTCGTGGCTCTGTTCGCCAAAGTCACGGTCGAACAGGACGACGCCTTGCTCGGCAACCAGATCTCCAGGTTCAACCGGCTATTCGGCGTGATGGCGGAGATTGCGGACGAATTAAAAGCGCGCGACGGCGACCAGCGCACCGCGCTTCTGAGCCTTTTCGAATACCCGAACATGCAGGTGCGGCTTCAGGCCGCGAAGCTCACGCTCGCCGTCGCACCAGTGAAGGCGCGTGAGCAGCTCGAAGCGATCGTATCCTCGAAATGGTTTCCACAAGCCGGCGACGCCGGCATGTGTCTCGATCTTCTGGATGATGGGACATTCAAGCCGAAATGACGACGTGGAAGGATGGAAACGCCGTCGTCAAGTTAGACATGGGGGCCATCAAGTTTTCAAGGTTCTCGGTCACTTGAGGCGTGAGAGCGGGCGCTGGACAACACCGAGAAGGAGTGTTGAACTGTGGGATCCGCCAAGTGGCTAATTTGTGGTCCTTATGCCGAGCGCCAAATCTCCCGTTGGGTTGCGTCGAAGTAGGGGTGCCTCAGAAGAGATCAATTCCGAGTAACATCGCTGTCGCAATCGGATGAATCGCTAATACTATTCTCAATGAAACGCTTCAGTTCGCCCTTCTTTATTTGCACGCCTATTCCTTTTAGGCACTCTTCTGCTGCGGAAAGCAGGGCGAATCTATCCTCTTTTCTCCAATGATTCCAGTAAACGCGATACGCGAAGTGGGCAGCAAGTGAGCTTCTTAAGAATGGTGACGGAGGCAGTTGTTTGATGGCAGATACAAGCATGTCCTTGCCTCGCTTGCTTTCGATGTCTGCTAGCCAAGCTGCGCGAATAATTTCTTCGATTGTTCCATGAACGGAAGCTTTCTCTACCGTAGTCGCAAGTACTCTCTGGCGAGCTCCCTCGCACAGTTGGTCAAGAACGCGTCTGACGCCGGTGCTCAACAAAGAGTATTCCAATACGTCGATCACGCCGCTAATGAATCGCTTGATTGTTTGTTCGTCTTGTTCATCAAGGTCTGAGATGGCTTCGATAAGCGGTTTATCTTCGAATATCTTGCGCTTGATTTCACCAAAATTGACCAGGAGCATTGCTTCGGTGGTGCGGTGAGCTATCACAGCAGATACTTGAACTAGCAGACTCGCCAGCATCTGCTTCATCTCAGCGTCAAGGTGCTCTGCTCCGGCGCCAAGAAGTAAGGTGCCAATTACCCAATTTTGGACGGCTATCCCCACACGGTCGAGCTCGTATGCTCGACGATCTTCGATACCGAATATTGCGCTATCTGCGGCTTCTTCTTTTACGCGATCGGCGACGTCCAGTATCCGCTGCTTCTTCTTTGTGTCGCCTCTTCCGTGTTCGATATCCTCTGCTGTCCTCTGAAGACGTTTCTGTATAGCCTCAATTTGCTCGGGTCGACTCATCATCGATGGACGGACTTTGTCGGTCAGTAAGATGTGCGTCTCGTCTGCCTTGAGGCCCCATTCGGATAGAGTTTCTTCGAGCCCCTCAATTATTCTGCACACCACGTGATCCGAAGCGCCGATCTCCGCATACAGGTCAAAGCAGTTCATGTTGAAGTCTGGGCCGAGGACAAAGTGTCGGGCGGCAGTCTGCGGCTCAGAAGCCAAAGCGCTTGCCAGTACGTAAGATTCTATGAATGGAAGCGAAAAGCCAACGCGATCGTTCTTAAAATGAAGAATGCCAGCGTCGACGAAGGAGTTAACAAAGGCGAGTGGATCAATCCCGAAGTCAAACTCTGTCGAAAATGATCGCGTAAAGGCAACCGTCTCCTCTTGACTGAATGAGTGCTTTTCGACGTTTAAGGCGATTGCGAGTCGCTTTAGGTATCGTAGTCTGGTTGTTCGGCTAAGTGCAACATCTGCGGTGTCGCCAGCGACAACAAACGACAAGAACCCGTCGACCGCCAACTGAATTAGTTCAGCACGTCGATTTGCTTGCAACAAGGCGGACAGAACTTCTCGTGGAATTCCTGCAAAATAGCTTGGATGTGCCGACAAATTGAAATGTTGAAAGGTTTCTCTCAGCCGAAGTGCAATGACTTCCGCTTCAGATCCCGTCATTCCAAAGTTCTTCTGAACAAAATGAGAGATCTCCAGAAACGAGATGCCGCAGAGCTCAAATGTGTCGGCTGTAACGATTTTGCCTAGTTCTGTTTCTGCGAGCTCAATAGTCTCGGCTCGCGTAATGAAGAGAAATTTGGCCGAAGGGTATTGGTCAATTTGTAGCCCAAGGTATTTGAGGCGGTTTTTCGACTTTATGGGAAGTCCATTGATGATGAATACGATCTGTATCCCGTCGTGATCTTTAAGGTGAGCAAAAGTGTATCCCGCCACAGCGGCAAATGACGATCTAGGGGGGGTAACGGATTCGCCATCTATTACGACTGGAATAATCTGCTTTCCATTAATCTCGGAAGTAAGTAGGTCGTTGGCTATCACCCAGGGTAGACTATTGTCCGGATAATGACGATTTAATCGCAGTAGCGCGTGGCTCCTGGTTATCAGGGCATCCCGTATCTCTGTGGGATCAGGTCGCGATCCAGATGATATCGTCTGGACCTGTCTCATTCTGGGGGTCGGTAGACGATATCCATATTGCTGAAGCCGGAAGTCTGGCGAGAGCTCCCGTAACTGTTCGTCGATGTGTTGACCGATATTAATGATCGTCGAAGTCAGGCTTGGTTCATTTGATTCTGGTCCGTTCTGCTCGGATGACTCAAAATGTTGGTGCGACAATCGCCGGCTTTTGACCGCTTCTACAAAGTACGGGTTTGAGAGTTGGAGGCGCAAAAACGTTGCGGCGTTAAGGGCGGCAAGTTTGCGAACGTTTCCGTTTGTTCGCTGCTCGAGTTGCGCTTTGTCTCCGTTCGCCATGTCAGATATGCCGCGAATGGTTAGTGCAATTATCGAGTGGCGACTCGCCTCTTGAAAGACACCGCCGGACTCTGTTTCGACGGCCGTCACTTTTCGGTCAATAGCGCGAAGCTTGTCGTTGTAAGTTTCGCTTTTGCTTACGGCGGCGCAGACGATAATTCCATCCGTAGTGATTGGTTTCGGTTCGTCTGGGCTCTTAAGATCGGTTAGTCCAAGCGCTGCAGCGTGTTTCGATTGCTCATTTTGCCAATTTAGATAGGCGGGCTTCAATTCTGGCTGGGTTCGGCAGAAATTGAGGGCAGTGACTATTTCGCGGGGGGTCGAGTAGTGTGAGAAGGAGAGGGAGACATCCAGTTGACCGCGCTTTTTGTCGGTTATGCTGGAGTTGTCGAGTACATCAGCGATTGTATTGCTGTAGCAAACGTCAGCCAAGCCGATATCTTTGGTAAGGCTTCCGGCGATGCCAAGACAAATAATTAGCCCAGCATCAAATTCGGCAAGTATGTCGGCGACAGCGCTGCGCGCAAATGTTCGGCCCATTCCTTCCTGTTGTACGACCAGCATTGTAATGTCGGGGCATGTGCTTAGTAATTCGTGTCGAAACGATGTAGCGGTTGAGAGGTTTGTCTTAGATGAGAACGTGTCCATAACTGCCTGGAGTTCTTCTTCGAGCGGAACTACGACAATAATGTCATACCGGCGTTTCGTCTGAGTGCGATCGGGTGGGATATTCGATTGAAGCATTATATTCTCTGTAAAATGCGGCTGGAGGACGGGATGAGTGCCGAGAGGGAGTCGAAGTTGATAGGTGATGCGTCGAAACGCAGACGGGATGGGGAGGTCGGCTGTCAGATGGTGCGTGCGGAACCGCGGGCGCTTAGGGCAGGTTCAGGTGCCTGGGCAATCTTCGCGTTTCGTGACGATCTGGACGCGTGGAAAGCATCGTGTTCTTCAGTGATAATGAATAGGCGGGGACAGCAGAAAGGCTGAGAGTGCTTATCAAGGTGGATGGGTGGTAGTATGGCCGTGATAACGGGAATGTCGCTGCGGATTGATTAGATTCTATCATGAGGCGTGGAATTGTGAACTGGGCGATTGGCGTCGTGGCTATTCATCTTTGGTTCTAGGAGGGGGAGTAGCGTGATATCCGAATTGTTTTGGTGAGTTGTGCAGCTTTAGTAAAGCTTTCCGTATTCAGTGATTGATGTCAATGTTGCGACGGGTTTTTAAGTACGACGATCCGATTTCGGTCGGAGGCTTGTGAGGATGTTGGATCGTCTTGGTAGTATGCGGTGAGGATTAGGGTGCGGATTCGGAGTTGGGGCGCTGCGGCAGATCGCCGGCCGTACTAGCGGTTCCGAGCAACGACTGCGCCGGTTCGCGCTGGTGGTTGAGCATCCGCCGCGGTGCGGCTGGCTGCAACATGGCAGCGCTTTCAGGCTGCCGCAACTGGTACGCTCACTGCTCCGCTGGCCGGCGCCGCAAGGCGTGGATGCCCGGCACAAGGCCGGGCATGACGGTGGAGCCGTTGATCGCCGAAATGCATGGCGGCCTGCTCGGCGGTGCAGGCCGAGGTCCGCCCGGTAGGGAGCTCTCTCATGCCCGACAATCCTCCGCCGCCCCGCTATTTGCCGCGCGGGCTGACGCCCGAGGCGGTCGCGGAGCTGAAGCGGCTGTACGAAAAGACCGACGTGCCGCTGACGGAGGTCGCGGCGCAGTTCGAGATCTGTCGGCACACGCTGCGCAAGGTGGCGGAGGCCGAGGGCTGGACGCCGCGGTTGGAGCGCCCCCGGGTCGGGCCGCGGCCGCCGCTGCCGGTCCGCCAGGCGCGCGGGTTTTCGCAGCAGGCGCTCGACGATCTGCGGCGGCGCTACGTCGAGACCGAAGAGCCGGTGCAGCGCATCGCCGAGGACTACCACATTCATCGCAACACGCTGGAGCGGCTGGCGATGCAGGAGGGGTGGCCGCGCCGCAAGGATCGGCCGCCGCGCGACATGCCGGTGCTGCTGCAGATCAATCGCGAAGCGACCGCGGCGCTGCAGCAGGCCCGCGCGATCGCCCCCGGCGCGCCGCTGCCGGGGTTGCCGCCGCCCGCGGCGGACACGAAGGCCGCGGGCGACACGGAGGCCGCGGCGCCTGCGCCCGAGAGCGAGGCCGAGATGGTGCCTGTGACCGAGGCATCAGCCGCAACGCCGGCGGACCAGGCGTCGCCCGAAGCGGCGCTGTCGTTGGCGCGGCGGCTGGAGCGCGCGGTCGAGACCCAGCTGCGCAAGGTCGAAAACCTGCGCGAGGACACCACGCTCGGCGGCCACCGCGCGGTCGAGGCCGAGCGGATCGCCCGCACACTGGCGGCGCTGACGCAGACGCTGTTCAAGGTCCGCCAGCTTCGCGATCCCGAACGCGCGCTCAGCGCCGCCGATGACGAGATGCCCGCCGATGCCGATGGATTCCGTCTGGAGCTTGCGCGCCGCATTGAGACGTTTGTCGGCGGCGGGACTGACCGAGCGCTTCCTGCGCCAGGCCAGCCTCCGGACGCTGGCTCACCTGCAGGATGATTTCGCCGTCTTCGCGCATCCGCATCAGGAGCCTGCGGATGCCGGCAACGACGGTGCGCCGTGGACTACCTGGCTGATGCTCGGCGGCCGCGGCGCCGGCAAGACCCGCGCCGGCGCCGAATGGGTGCGGGCGATGGTGGCCGGCACGCCGCCTTATGCGACGCGGCCGCACGGCCGGATCGCGCTGGTCGGCGAAAGCTGGCACGACGCCCGCGAGGTGATGGTGGAAGGCGAATCCGGCCTGCTGCGGATCACGCCGCGCCGCGAGCGCCCGGAATGGATCGCCACCCGCAAGCGGCTGGAATGGCCGAACGGCGCGGTCGGCGAGGTGTTCTCCGCCGACGATCCGGATAGTTTGCGCGGTCCGCAATTCGAGGCGGCGTGGTGCGACGAGCTGGCGAAATGGCGCTACGCCGAAGCCAGCTTCGACATGCTGCAATTCGGGCTGCGGCTCGGCTCCCGGCCGCGGCAACTGATCACCACGACGCCGCGGCCGCTGCCGCTGATCAAGCGGCTGCTCGGCGATCCGCATACAAGGGTGACGCGGGCGCCGACCCGCGCCAACGCCGCGCATCTGTCGCCGGCGTTTCTCGAAACCGTGGTGGCGCGCTACGCCGGCACAAGGCAGGGCCGGCAGGAGCTCGACGGCGAACTGATCGAGGACCGCCCCGACGCGCTGTGGTCACGCGACCGGATCGAGCGCGCCCGCGTCGCGGCGGCGCCGCCGCTGGTGCGGATCGTGGTGGCGATCGATCCGCCGGGCTCGTCGCGGCCGGGGGCGGACGCCTGCGGCATCGTCGCGGCGGGGCGCAGCGCGGCCGGCGATTACTACGTGCTGGAGGACGTCTCCAGCGACCGGCTGTCGCCGGCGGCCTGGGCGGCGCGCGCGATCGCGCTGTATCACCGGCTCGAGGCCGATGCGATCATCGCCGAGGTCAATATGGGCGGCGAGATGGTGCGCGCGGTGCTGCACGAGACCGACGCGGCGATCCCGGTGCGCGAGGTGCGCGCCAGCCGCGGCAAATTCGTCCGCGCCGAGCCGGTGGCGGCGCTGTACGAACAGGGCCGGGTGCGGCACGTCGGCTGCTTTCCGCTGCTCGAAGACGAGATGTGCGATTTCGCACCCACCGGGCTCTCCTCCGGCCACTCGCCGGACCGGCTCGACGCGCTGGTGTGGGCGATCACCGCGCTGATCGGCGGCGCCCATGCCGGGGGCCCAAGGATGCGGGTGTTGTGAGGGCGAAGTGGAGTGGATGGTCTGGTGCGACGGCATGGCGGCGGAACCATCGCGGGCGGCGACGGGTTGCTGCACCATCAACGCGGAAAGGTGACGCATGAGCCGTTCGATCACGATCATGATGGCGATGGTGCTGGGGTTGGCGGCGCTCGGCGCCGGCCTGATCGCCGGCAGCGGCGCGGCGCTGGCTCGCGGCGGCGCCGCCAACATCATGGACTCGCCGGGCTATCAGCGCGCGCTGCAGGAATCCCGCAAGCGGCAGCAGCAGCAGCCGGGGCCGTCGATGGCGCAGCCGTTCGCCGCGCCGCCGGTGGCATATCCGCATCCTGAGCGTCGGGTCGGGCCGAAGCGGCGGCATCGCGCGCCGCGGCATTGAGCTGTCGCGCGTCGCGCGCTCAGCAGTAGCCGTACCAGCCGCAGGCGTAGGGCAGGCGGCCGAAGATCAGGTTCGGATCGGTGCCGTAATAGCTGCGGTACAGATACGAGCGCGGCTTGCCGTAGTAACCGTGCACGATCGGCGGCACGTCGACCTCCGGCGCATACACCGGCGAGCCGCTCTCCATCTCCAGCGATTGCCGCACCCGCGGCTTCGGTTGCGGCTCCGCGAAGATCTTGCCGATCTTGCTGTGCATCGGCAGATCGGCCGCCCGCGCCGCCGGCTGGGCCAGCGGCAACGCGATCAGCAACAACAGCACGACACGCAACATGGCGGCACTCCAGGGTGAGATGCCGCGAGGGTGGGCGATTATGGTTAATAAAGATTAACCAACGCCGTGCCCGGGGAGCCGCTATCGGCTGAGCGCCGAGCCCCAGCTCTGCGCGGTGCGGGCGATCCAGTCGCGGTACAGCGTCAGCGGGGTGACGCCGGTGAGGCCGCCGCAGCCGGCGGTGTTGCCGGGGCCGGTCGACCACGACACCACGCCGACCACCACCAGCCGGTCGTTCTGCGCCTGCAGCGCCGGCCCGCCGGAATCGCCGGTGCAGGCCCCGAGGCCCGCGCGGCCGTCGGTGGCGGCGGGATCGGTGAGGCGGATCTGCAAGCGGCCGGGGCGGCCGGTCGCGGTCAGCGTCGCGCTGCGCGCGGTGCCGCCGCTTTTGCCGTCGCCGCGCCGGGTGACGCCGATGCCGGCGACGGTGAAATCCTGGCCGGCGGCGAGCGGATCCTCCGGCGCGGCGATCGGCAGCGGCGCCTTGCCGGGCAGCGGCGCGGCGAGCTTCAAAAGCGCGACGTCGGCGCTGGCGCGGTGGCCGAGGATTGCGCCCATGTCGAACTCCGGATGCGCGGCGACGCGGGCGACATCCCGCAGGCTCGGCTGCCGCTGCGCGTCGTATTGCACCACCTTGTAGTCCGCGCCGGGGCCGACGCAGTGCGCGGCGCTCAGCACCAGGTCGGGCGCGATCAGCGTCCCCGAACAGAAATTGCCGCGCGAGCCGACGATGGTGACCAAAGCGCGGCCGAGCGCGCCGGTCGCCTCGGGGGCGCCGCCGACCATTGCGGCGGCCGGTGAGGCGAGCGCGGCGCCGAGCAGACAGCCGAATGTGAGCGTGCGGATCATGGCGGCGCGTTTCGCCCGCCGCCGCGGCGCTGTCAATCGCCGATCACCATCACGAGGAACCGCCATGCCAATGCTGCTGCTGGCCGGGCCGGCCGCCGAGCCGTGGACCGTCACTGATCTGAAGAGCTTCCTGCGCGTCGAGCACGAGGCCGACGACGCGGTGATCGCCTCGCTGCTGACCGCGGCGCGCGCCCAGATCGAGGCGAGTACTTGCAAGATGCTGCTGGCGCAGCGCTGGCGGCTGGTGCTGGATGCCTGGCCGCGCGACGGCCGCCTCGTGCTGCGCAGCGGCCCGCTGCGGTCGCTGATCGCGGTGCGGACCTATGACGAGCGCGGCTACACGCATGGCCTCGATCTCGACAGCTTCGTGCTCGACCTCGCCGGCGGCGTGATCGCGTCGCCGCCCTGGGCGCTGCCGGAGCCGGGGCGCGCGGTCGCCGGCATCGAGCTCGACCTCGAGCTCGGCTACGGCACCGCGCCCGAAGATGTCCCGCCGCCGCTGCGCCACGCGGTCCGCACCCTGGCGGCGCAGTGGTACGACAACCGCGGCAGCGGTGCCGGCGCTGCGCTGCTGCCCGGCGGCGTCGCCGCGATGATCGCCGGCTATCGCGCGGTGGCGCTGTGATCGATCCCGGCCGCCTCAACCGCCGGCTGACGCTGCTGGCACCGGTCGAGACCGACGACGGGCAGGGCGGCGTGGTGCGGAGTTTTGCGGCGCAGGCGGTGCTGTGGGCCAGCGTCGTGCCGCTCGCGGCGCGCGAAGGCGTCGCGGCTGATGATAGCCGCGCGGCGCTGCGCGCCAAGATCACGCTGCGTGCTGGGGTGGCGCTGTCGCGCGCGCATCGGCTCGCCGACGGCGACAGTGTGTATCGCATCATCGCCTGGCGCAGCCGCGAGCGCGGCGCGCTGCTCGAAATCGACGCCGAGACGGAGCAGACATGA

Protein sequences of DBSCAN-SWA_1

>NC_005296|2118612:2131987|2123339_2126441_-|WP_011157396.1|DBSCAN-SWA
MLQSNIPPDRTQTKRRYDIIVVVPLEEELQAVMDTFSSKTNLSTATSFRHELLSTCPDITMLVVQQEGMGRTFARSAVADILAEFDAGLIICLGIAGSLTKDIGLADVCYSNTIADVLDNSSITDKKRGQLDVSLSFSHYSTPREIVTALNFCRTQPELKPAYLNWQNEQSKHAAALGLTDLKSPDEPKPITTDGIIVCAAVSKSETYNDKLRAIDRKVTAVETESGGVFQEASRHSIIALTIRGISDMANGDKAQLEQRTNGNVRKLAALNAATFLRLQLSNPYFVEAVKSRRLSHQHFESSEQNGPESNEPSLTSTIINIGQHIDEQLRELSPDFRLQQYGYRLPTPRMRQVQTISSGSRPDPTEIRDALITRSHALLRLNRHYPDNSLPWVIANDLLTSEINGKQIIPVVIDGESVTPPRSSFAAVAGYTFAHLKDHDGIQIVFIINGLPIKSKNRLKYLGLQIDQYPSAKFLFITRAETIELAETELGKIVTADTFELCGISFLEISHFVQKNFGMTGSEAEVIALRLRETFQHFNLSAHPSYFAGIPREVLSALLQANRRAELIQLAVDGFLSFVVAGDTADVALSRTTRLRYLKRLAIALNVEKHSFSQEETVAFTRSFSTEFDFGIDPLAFVNSFVDAGILHFKNDRVGFSLPFIESYVLASALASEPQTAARHFVLGPDFNMNCFDLYAEIGASDHVVCRIIEGLEETLSEWGLKADETHILLTDKVRPSMMSRPEQIEAIQKRLQRTAEDIEHGRGDTKKKQRILDVADRVKEEAADSAIFGIEDRRAYELDRVGIAVQNWVIGTLLLGAGAEHLDAEMKQMLASLLVQVSAVIAHRTTEAMLLVNFGEIKRKIFEDKPLIEAISDLDEQDEQTIKRFISGVIDVLEYSLLSTGVRRVLDQLCEGARQRVLATTVEKASVHGTIEEIIRAAWLADIESKRGKDMLVSAIKQLPPSPFLRSSLAAHFAYRVYWNHWRKEDRFALLSAAEECLKGIGVQIKKGELKRFIENSISDSSDCDSDVTRN
>NC_005296|2118612:2131987|2119813_2120014_+|WP_011157392.1|DBSCAN-SWA
MSDLIKMFSERGDLAHVALLLWAIGASLGLWFVLREWAAAVRRFDDFVHALDLFNRRARRRAQDEE
>NC_005296|2118612:2131987|2131666_2131987_+|WP_011157403.1|head,tail|DBSCAN-SWA
MIDPGRLNRRLTLLAPVETDDGQGGVVRSFAAQAVLWASVVPLAAREGVAADDSRAALRAKITLRAGVALSRAHRLADGDSVYRIIAWRSRERGALLEIDAETEQT
>NC_005296|2118612:2131987|2118612_2119788_+|WP_011157391.1|portal|DBSCAN-SWA
MFDRLKAFLTVPEAKTSRTAQLLAVGFGGVARFTPRDYAGLAREGYVRNAIVYRCVRLVAENAAACVFGVFDGAQEKEAHPLAALLARPNPRQDGAALLETLYAHLLLAGNAYIEAVTLGEAVHELYALRPDRIKLIPGTDGWAEAYDYSVAGRTVRFDQHATPVPPILHLTFFHPLDDHYGLAPLEAAAVAVDTHNAAARWNKALLDNSARPSGALVYAGPEGAVLSENQFERLKRELENTYEGAANAGRPLLLEGGLEWKAMALSPKDMDFLEAKHAAAREIALAFGVPPMLLGIPGDNTFSNYQEANRSFVRQTVLPLATRVGNALAQWLSPQFGDGVRLVIDTDRIDALSPDRTALWDRVTRAPFLTLNEKREAVGYAPIEGGDRLG
>NC_005296|2118612:2131987|2127295_2128252_+|WP_011157397.1|DBSCAN-SWA
MPDNPPPPRYLPRGLTPEAVAELKRLYEKTDVPLTEVAAQFEICRHTLRKVAEAEGWTPRLERPRVGPRPPLPVRQARGFSQQALDDLRRRYVETEEPVQRIAEDYHIHRNTLERLAMQEGWPRRKDRPPRDMPVLLQINREATAALQQARAIAPGAPLPGLPPPAADTKAAGDTEAAAPAPESEAEMVPVTEASAATPADQASPEAALSLARRLERAVETQLRKVENLREDTTLGGHRAVEAERIARTLAALTQTLFKVRQLRDPERALSAADDEMPADADGFRLELARRIETFVGGGTDRALPAPGQPPDAGSPAG
>NC_005296|2118612:2131987|2122752_2123124_+|WP_011157395.1|DBSCAN-SWA
MSKLDLHQMTTQDLVALFAKVTVEQDDALLGNQISRFNRLFGVMAEIADELKARDGDQRTALLSLFEYPNMQVRLQAAKLTLAVAPVKAREQLEAIVSSKWFPQAGDAGMCLDLLDDGTFKPK
>NC_005296|2118612:2131987|2129884_2130196_-|WP_011157400.1|DBSCAN-SWA
MLRVVLLLLIALPLAQPAARAADLPMHSKIGKIFAEPQPKPRVRQSLEMESGSPVYAPEVDVPPIVHGYYGKPRSYLYRSYYGTDPNLIFGRLPYACGWYGYC
>NC_005296|2118612:2131987|2121167_2122421_+|WP_011157394.1|capsid|DBSCAN-SWA
MTTFDHAPETKAGFAGDDAQQVFDALMRAFEDYKAENDARLKAIETGKGDVLAEEKLARIDAALDHQQRRLDELALKAARPQLAAERPQPAADQREHKSAFEAYVRTGEAASLRRLETKALSAGSAPDGGYLVPTELEHTISSRLAAISPIRSLSTVREISGGVYKKPFVTAGPATGWVGEGDARPQTNAPSLDALSFPAMELYAMPAATATLLDDSAVNIDDWLAGEIDQAFAEQEGIAFVSGDGVSKPKGFLAVPTAANSAWSWGKLGTISTGAAGAFAATAPGDVLIDVIYALRPGYRQNASFVMNRRTQAAIRKFKDSSGAYLWQPPVTAGGRASLAGFPLADAEDMPDIAANSLSIAFGDFRRGYLIVDRQGVRVLRDPYSSKPYVLFYTTKRVGGGVQDFDAIKLVKFAAS
>NC_005296|2118612:2131987|2130277_2131045_-|WP_042440958.1|protease|DBSCAN-SWA
MIRTLTFGCLLGAALASPAAAMVGGAPEATGALGRALVTIVGSRGNFCSGTLIAPDLVLSAAHCVGPGADYKVVQYDAQRQPSLRDVARVAAHPEFDMGAILGHRASADVALLKLAAPLPGKAPLPIAAPEDPLAAGQDFTVAGIGVTRRGDGKSGGTARSATLTATGRPGRLQIRLTDPAATDGRAGLGACTGDSGGPALQAQNDRLVVVGVVSWSTGPGNTAGCGGLTGVTPLTLYRDWIARTAQSWGSALSR
>NC_005296|2118612:2131987|2128193_2129489_+|WP_042441497.1|DBSCAN-SWA
MTERFLRQASLRTLAHLQDDFAVFAHPHQEPADAGNDGAPWTTWLMLGGRGAGKTRAGAEWVRAMVAGTPPYATRPHGRIALVGESWHDAREVMVEGESGLLRITPRRERPEWIATRKRLEWPNGAVGEVFSADDPDSLRGPQFEAAWCDELAKWRYAEASFDMLQFGLRLGSRPRQLITTTPRPLPLIKRLLGDPHTRVTRAPTRANAAHLSPAFLETVVARYAGTRQGRQELDGELIEDRPDALWSRDRIERARVAAAPPLVRIVVAIDPPGSSRPGADACGIVAAGRSAAGDYYVLEDVSSDRLSPAAWAARAIALYHRLEADAIIAEVNMGGEMVRAVLHETDAAIPVREVRASRGKFVRAEPVAALYEQGRVRHVGCFPLLEDEMCDFAPTGLSSGHSPDRLDALVWAITALIGGAHAGGPRMRVL
>NC_005296|2118612:2131987|2120318_2120996_+|WP_011157393.1|head,protease|DBSCAN-SWA
MLAPSPALAPSLSPAPLPARLSLAEDGSIDGYASLFGEIDQARDMVMPGAFTQTLKQRGLRKIPMLFQHDPAEPVGVWLELAEDLRGLRARGRLIPDVARGRELLALLRAGAIDGLSIGYRTVRGQIDPRTRVRRLYQVDLWEISIVTFPLLSGARIATVKHTPRPSPQRAAAEAAWRRVHDAAATRSGDAAEAPASPIRRGRIAATLSTRAGRKQALASFSRRG
>NC_005296|2118612:2131987|2131109_2131670_+|WP_011157402.1|head,tail|DBSCAN-SWA
MPMLLLAGPAAEPWTVTDLKSFLRVEHEADDAVIASLLTAARAQIEASTCKMLLAQRWRLVLDAWPRDGRLVLRSGPLRSLIAVRTYDERGYTHGLDLDSFVLDLAGGVIASPPWALPEPGRAVAGIELDLELGYGTAPEDVPPPLRHAVRTLAAQWYDNRGSGAGAALLPGGVAAMIAGYRAVAL
>NC_005296|2118612:2131987|2120018_2120195_+|WP_162843677.1|DBSCAN-SWA
MQRLSSVLSRVRAETKSARDPQAIFREFLAHLSGAQHKPAPRRAAPKPPRKRSAKRAK
>NC_005296|2118612:2131987|2129586_2129865_+|WP_011157399.1|DBSCAN-SWA
MSRSITIMMAMVLGLAALGAGLIAGSGAALARGGAANIMDSPGYQRALQESRKRQQQQPGPSMAQPFAAPPVAYPHPERRVGPKRRHRAPRH

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011157391.1|2118612_2119788_+|portal	phage portal protein	W8ECU7	Geobacillus_phage	2.1e-76	41.0
WP_011157392.1|2119813_2120014_+	hypothetical protein	NA	NA	NA	NA
WP_162843677.1|2120018_2120195_+	hypothetical protein	NA	NA	NA	NA
WP_011157393.1|2120318_2120996_+|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	1.7e-30	49.0
WP_011157394.1|2121167_2122421_+|capsid	phage major capsid protein	Q3HQT0	Burkholderia_phage	9.0e-73	39.8
WP_011157395.1|2122752_2123124_+	DUF2019 domain-containing protein	NA	NA	NA	NA
WP_011157396.1|2123339_2126441_-	hypothetical protein	NA	NA	NA	NA
WP_011157397.1|2127295_2128252_+	hypothetical protein	NA	NA	NA	NA
WP_042441497.1|2128193_2129489_+	DNA-packaging protein	A0A0U4IJ26	Arthrobacter_phage	9.9e-75	39.9
WP_011157399.1|2129586_2129865_+	hypothetical protein	NA	NA	NA	NA
WP_011157400.1|2129884_2130196_-	hypothetical protein	NA	NA	NA	NA
WP_042440958.1|2130277_2131045_-|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_011157402.1|2131109_2131670_+|head,tail	phage head-tail connector protein	NA	NA	NA	NA
WP_011157403.1|2131666_2131987_+|head,tail	head-tail adaptor protein	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_005296|3219530:3226156|DBSCAN-SWA
GTCAGAAGCACAGGCCCAGCATCTTGATGCTGCAGTCACGCTGCACCGACTTCGGCTGAACCGACTTGGGCTGAACCGACTTGGGCTTCGCCGGCTTTTCCTTGTCGGCCCCCTTCGCGGAAGTTGCAGCAGGCTTGGCTGACTTTGCTGGCTGCCTGGCTTTCGGCTTCTCGTCGCCGCCGGCGATCACCATCGCCCAATAGGTCCGGCCGCTCGCGCTCGATCTGACACTGGCGACGCCGACCTTGGAGGCGCCTTTCAGCAGCAGGTTGGCGCGGTGGCCCGGCGAGTTGATCCACTGCTTCAGCGTGTTCGGAAAATCCGGATAGCCGTAAGCGATGTTCTCGGCGGCGCGCGACACGTTGGCCGGCGCCACGCGCGAAGTGAACGAGCCGCCGGCTTCGTGACTGAGGACGTCCTTCGATGCCATTGCGACGGCCTGCCGCTGCGCGATCGCATTCAGCGTCGCGTCCATCACCACCTTGCCCTCGCCGTTCTTGGCGCGGAAGTCGGAGATCATCTCGGCGGGCCCGGCGGCGAAGGCGGGAGCGCTCGAAGTTGTTATCACCGCCAGTATTACCGTCATTGCGAGGAGCGCAGCGACGAAGCAATCCAGCACCGTGCACGGGGCCGTTGATTGCTTCGATGCGCTCGCAATGACGGGGAAAGACATCAGCCTTACGCCTTCGCGATCACCTTCAGCCCGCCCATGTAGGGCTGCAGCACGTCGGGGACGGCGATCGAGCCGTCTTCCTGCTGATAGTTCTCGATCACCGCGATCAGCGCACGGCCGACGGCGGTACCGGAGCCGTTCAGCGTGTGGACGAAACGCGGCTTGCCGTCCGAACCGCGCGAGCGCGCGTCCATGCGGCGGGCCTGGAAGTCGCCGCACACCGAGCACGAGGAGATTTCGCGGTACGCACCGCCCTCGCCCTGCCCCGGCATCCAGACTTCGATGTCGTAAGTCTTCTGCGACGCAAAGCCCATGTCGCCGGTGCACAGCGTCATCACCCGGTAATGCAGCCCGAGCCGGCGCAGCACTTCCTCGGCGCAGGACAGCATCCGCTCGTGCTCGTCCTTGCTCTGCTCGGGCGTCGTGATCGACACCAGCTCGACCTTGGTGAACTGATGCTGCCGGATCATGCCGCGGGTATCACGCCCCGCAGCGCCCGCCTCAGCGCGGAAGCACGGCGTCAACGCTGTGAGGCGCATCGGCAGCTCCTTCTCGTCGAGGATGGACTCGCGAACGAGATTGGTCAGTGAGACTTCGGCGGTGGGGATCAGCCAGTAACCCTCGCCACCGCTGCCAATCGCTCCGGCCGCGAACTGATCCTCGCGAAACTTCGGCAGCTGAGCGGTACCGAACATCGCGTCGTCCTTCACCAGCAGCGGCGGATTGACTTCGGTGTAGCCGTGGTCGCCGGTGTGGACGTCGAGGAAAAACTGACCGATCGCGCGTTCGAGCCGCGCGAGGCCCTTCTTCAGCACGGTGAAGCGCGCGCCGGAGAGTTTGGCCGCGGCTTCGAAGTCCATCATGCCGAGCGCTTCGCCGAGGTCGTAATGTGGCTTCGGCGTGAAACTGTAGCTCGGCTTTTCGCCGAAGCGGTGGTGCTCGACGTTGCCGTGTTCGTCGGCGCCTTCCGGCACCTCTGGCAGCGGCAGGTTCGGGATTTCCGACAGCGCCTTTTTCAGCGCCTCGTCGGCTTCCTTCACCGCCGCGTCGAGCGCCGGCATCGTGGTCTTCAGCTCGGTGACCTCGGCCATCAGCGCCTCGGCGCGGGCGTTGTCCTTGGCCTTCTTGGCGTCGCCGATCTCTTTCGACGCCGCATTACGCCGCGCCTGCGCCTGCTCGGCGGCCTGCACCGCCGCGCGGCGGACTTCGTCGAGCTTCATCAGGCTACCTGCGATCGGCGCCAGACCGCGCCTCGTGAACGCCGCGTCGAAGGCCTGCGGATTGTCGCGGATCGCTTTGATGTCGTGCATGGAATCGCCTCGTCAGGCCGGGCCCGTCCCGGCCGTCCGCGTGTCGCGGAGCAACGTCTGTAGAAGACGGCAATGCCCGGCACAAGGCCGGGCACGACAACGGAGACAGGTCAGAACTGCCAACTCAACTGGCCGCGCACCTGATCGCGACGGACCCGCTCGCCGGTGCTGCGGAACGCCAGATCCGCGATCGGCGCCGTGGCACCGAATGCGTGCTGCCAGGATGCCACCAGCCGGGGCATCGCCACCAGACCGGCGAAAGCGTAAAACTGGTCGTCAGCCGGCTGCCCAGCGTTGAAAAGCCGGCGTCATCGTTGCGGCCTGCTCCCGAGAGAGCGGTGATGCCGCCGCCTTCTACAAACCCATCGCGATGCAGATGCACCAGCGCCAGCCCGCCGAACGGCTCGGCGACGGCCTGCCCGACCGCCACGCGGTAGCCGATCTCGCCGAACGCCTGCGCGGTGGTGGCATCATAGCGCGCACCAGCGAGGCCGACATGCCAACAAATCGGATTTGCGGCGTCAACATCGCGGACGCCGAAGTCCTTTCAGAGAGAGGAAACAGCCGGGCTTAGGCGGCCGGTGTCGAGGAGTCGGTGCTGGCGTTGGCGCTAGCGCTAGCGTCTGCCGCAGCGCGCTTCTTCTCCACCATCGACACCGCGATGATCGAGCCCTCGTACAGCAGCAGCAGCGGGATCGCGAGCGAGGCCTGGCTGATCACGTCGGGCGGGGTCAGCACCGCGGCGATGATGAAGGCGCCGACGATGAAGTAGCGGCGCTTCTCCTTGAGCTGCTTGGCGGTCAGCACGCCGATCCGGCCGAGCAGCGTCAGGATCACCGGCAACTGGAACGCCAGGCCGAACGCAAAGATCAGCGACATCATCAGCGACAGATACTCGCCGACCTTGGGCAGGAGCTGGATCTGCGCGGTCTCGGCGCCGCCCATCTGCTGCATGCCGAGCGAGAACCGCACCAGCATCGGCAGCACCAGGAAGTACACCACCAGCGAGCCGAGTAGGAAGAAGCCCGGGGTGGCGATCAGGTACGGCACGAAGGCGTTGCGCTCGTGCTTGTACAAGCCCGGCGCGACGAATTTGTAGATCTGGGTAGCGATGATCGGGAACGAGATGAAGCCGGCGCCGAACATCGCCAGCTTGAGCTGGGTGAGGAAGTATTCGAGCAGCGCGGTATAGATGAACTTGGAGTTCTCCGGCCCCGCGACCCAGACGAACGGCCACACCAGCACATTGTAGATCTGCTTGGCGAAGAAGAAGCAGAAGATGAACGCGATGCCGAAGCCAAGCAGCGCCTTGATCAGCCGCGACCGCAGCTCGATCAGGTGGTCCATCAGCGGCGCCTTGGAGGCCTCGATATCCTCGGCACTCATGACGCTTTGGCGTCCTTGGTCGGTTCGGGATGCGCCAGATCCGGAGGCGCGGCATCAGGCGTGGCAAGCGCGTGCGTTTCGGCCACGACCGGCAGGTGCGGCGGTTCAGTACCCTGGGCTTCACGCACGATCGCCAGCGGCTCGGACGCCGCGGCATCATGCTGGGTCGCCTCGACGAAGGTCTCGGCGGTCGGCTGCGCTGGCGTTGTCGGCTCGGCCGGTGGGGTATCGATGTTGGTGGCCTTGTCGAGCGCCATCGCGTCGGTGACCTCGCTCGACAGCTTGGTGAGCATGTTGTTGGTGGACAGCCCGCTGGTGGCTTCCTTGACCTCGTCGAACGACTTCTTGAGGTCGGCCATCTCAGCCTCGCGCATCGCTTCCTGGAACTGCCCCTGAAATTCGGTGGCGAGCCGCCGCGCCTTGCCCATCCACTGCCCGACCGTGCGCAGCACGCCCGGCAGTTCCTTGGGGCCGATCGCGATCAGCGCGACCACCCCGATCACCATCAGTTCACTCCACCCGATGTCGAACATGAAACGTGCCGACTATGCCTCAATGCGCCCGCGCATCTGCCGGGACGCTTCCGGGCGCGCCCCGCCGTCCCCGCGGTGCGCTCACCCTCTGGTCATCCGGCGGCGCGTGCCGTCGCCGGATCAAGCGGCCCGGCAGGCGATGCCGCACGGGCTCGAAGACGGATCAGGTGCGTGCGGGGCGACTGCGCCTCAGACCGCCTTGCTGCCGACGTCGGTGCGGTTGGTCGCGCCGGGCGTCGAGGTGTGGTCGATCGACTTCACCGGCTCGGACTTTTCGGCCGTCTTTTCATCGTCCTGCAAGCCCTTCTTGAAGGACTTGATACCCTGGGCGACGTCGCCCATCAGGTCCGAAATCTTGCCACGACCGAACAGCAGCAGGACGACCGCGATAACGACGATCCAGTGCCAGATACTGAGTGAACCCATCCTGCCTTCTCCCGAAACTCGACCGGCGCGCCAGCCCTATTCACTTGCGAAGCTAGGTGAAAGAGCGGCCCGAAACAAGGATTTAAGCTGTCGCAACGGCGAGTTGATCGCGCCCGATCCAGTTCCTTGCCAAGCGTCGCGCTGACTTACTGGTGCTGATCATCCTCGCCGTGGGCGTCGTGCTCGGCGTCCTCTTCGGAGCCCTCCGGTTCAGCGGTATCGAGTTCCGGAGTATCGGTGTGGCCGGTCTCGTCATTGCCGGCTTCGACATCGTCGGACGCGACCTCGTGCGCCTCTGCGACGACGTCCTCGTCCTGATCATCCGAGGCGACCAGTTCCACTTCGACGGTCTCGATCTCGATGCTGACGTCGTCCTCGATATCGAAATCGTCGGCGTCAGCCTCTTCGGCTTCCAGCTCGCGATCGCCGACCTCACCAACCTCGACAGCGTCTTCGATCTCGCCAGCCTCGTCGGCATCCTCGGTCTCGGCGAAACCGGTTTCGGCCTCGGCCTCATCGTCGGACGTCTCGGCAAAGCCGGTCTCGGCCTCCTCCGCATCGTCCTCCGAAGTCTCGGCGAAACCAACCTCGGGCGCGGCCCCGTCGTGCGCGGCGGCTTCGGCCACGCCAAGCTCGGCCTCGCCGGTCTCCGCGGCTCCCGTGGCCTCGGCGGTTGCGGACACGCCAGCTTCGTCGGCGGCCGCGGCGTCGCCCTCCAGATCCAGCTCGGGCTGCGGCGCCAGCGACAGGTCGAGATCGCCGGGCTCGAGCGGGTCCTCGTCTTCGCGCAGCGCCGGATCGTCCGACGGCGTCGGCACGCTGAAGCCGGTCGGCAGGCGGGTGTCGAGCAGGCCGGTGCCCTTGAGTTCTTCGAGGCCCGGCAGGTCGGTGAGCGACTCCAGGCTGAACTGCGACAGGAACGCTTCGGTGGTGCCGAAGGTCAGCGGCCGGCCCGGAGTCTTGCGACGGCCACGCGGCTTGACCCAGCCGGTCTCCAGCAGCACGTCGAGCGTACCCTTCGAGGTCGCCACGCCGCGGATCTCTTCGATCTCAACACGGGTGATCGGCTGGTGATAGGCTATGATCGCCAGCATCTCGATCGCGGCACGCGACAGCTTGCGAGTCTCGGTGGACTCGCGCGTCATCAGCCACGCGAGATCGCTGGCGGTGCGGAACGTCCACTTGTTGGCAATGCGGACGAGATTCACGCCACGGCTGGCGTAGTCCTCTTGTAATTGCTTCAGCGCGACCTTGACGTCCACGCCTTCCGGCATGCGCTTGGCGAGCGCAGCCTGATCGAGCGGCTCGGGGGACGCGAACAGCAGGGCTTCGAGCAGGCGCAGCTCCTCGGGCCGGGACTGCGGCTGCTGTTCGGCGCTGTCATCAGCGAGATGTTCGACCGGCTGTTCGAACTCCACGATGCGCTTCTCCGCCAGACTTGCCATGGCTCGGTCTCCTTCTTCCACTACCCGACCGGAGTATCCGGTAAGGCTGCCGCTTCCATCGCTGGAGACGGCGGACGCTTACGAAAATACAAAGGCGCCAAGGGGCCCGACTGATGCAGCTCGACTTCACCTTCGCGCACCAGCTCGAGCGCGGCGGCGAAGCTCGACGCCAGCACGGTGGCGCGCTGGGTCGGATCGGGCATGTAGCGCAGCAGATATTCGTCGAGCCGGCTCCAATCCTCGGCGAGCCCGACCAGGCGCTCCAGCGACGCGCGCGCTTCGCTCAGCGACCACACCGTGCGCTTGGCGAGATGCACGGTCGTGAGCACGCGCGACTGACGCTGCGACGCGTAGGCACTGAGCAGGTCGTACAGCGTCGCCGTGAATTTCGGATGCTTGATCTCGGCGATCTCTTCGACCTGACCGCGCGGGAAGATGTCGCGATTGAGCTGGGCGCGGGTCATCAGCCGGTTCGCGGCTTCGCGGATCGCTTCGAGGCGGCGCAGCCGGTTGGCCAGCGCATTCGCCATGTCCTCGGCACTCGGGCCTTCCTGGGCCGGCGGCTCCGGCAACAGCAGGCGCGACTTCAGGAAGGCGAGCCACGCCGCCATCACCAGATAGTCGGCGGCGAGTTCAAGCCGGATCTTCCGCGCTTCTTCGATGAACAGCAGATACTGATCGGCCAGCGCCAGGATCGAGATCTTGTGCAGGTCGACCTTCTGCTGCCGCGCCAGCGTGAGCAGCAGGTCGAGCGGGCCTTCATAACCCTCGACGTCGATCACGAGCGCTTCGTCCTGGTCGGCCTGCTGCTCGACAGGCCGGCCAGTTTCGAATTGCAGAATCTCAGCGGTCAT

Protein sequences of DBSCAN-SWA_2

>NC_005296|3219530:3226156|3221636_3222020_-|WP_079403165.1|DBSCAN-SWA
MCWHVGLAGARYDATTAQAFGEIGYRVAVGQAVAEPFGGLALVHLHRDGFVEGGGITALSGAGRNDDAGFSTLGSRLTTSFTLSPVWWRCPGWWHPGSTHSVPRRRSRIWRSAAPASGSVAIRCAAS
>NC_005296|3219530:3226156|3219530_3220202_-|WP_011158393.1|DBSCAN-SWA
MSFPVIASASKQSTAPCTVLDCFVAALLAMTVILAVITTSSAPAFAAGPAEMISDFRAKNGEGKVVMDATLNAIAQRQAVAMASKDVLSHEAGGSFTSRVAPANVSRAAENIAYGYPDFPNTLKQWINSPGHRANLLLKGASKVGVASVRSSASGRTYWAMVIAGGDEKPKARQPAKSAKPAATSAKGADKEKPAKPKSVQPKSVQPKSVQRDCSIKMLGLCF
>NC_005296|3219530:3226156|3220207_3221512_-|WP_011158394.1|tRNA|DBSCAN-SWA
MHDIKAIRDNPQAFDAAFTRRGLAPIAGSLMKLDEVRRAAVQAAEQAQARRNAASKEIGDAKKAKDNARAEALMAEVTELKTTMPALDAAVKEADEALKKALSEIPNLPLPEVPEGADEHGNVEHHRFGEKPSYSFTPKPHYDLGEALGMMDFEAAAKLSGARFTVLKKGLARLERAIGQFFLDVHTGDHGYTEVNPPLLVKDDAMFGTAQLPKFREDQFAAGAIGSGGEGYWLIPTAEVSLTNLVRESILDEKELPMRLTALTPCFRAEAGAAGRDTRGMIRQHQFTKVELVSITTPEQSKDEHERMLSCAEEVLRRLGLHYRVMTLCTGDMGFASQKTYDIEVWMPGQGEGGAYREISSCSVCGDFQARRMDARSRGSDGKPRFVHTLNGSGTAVGRALIAVIENYQQEDGSIAVPDVLQPYMGGLKVIAKA
>NC_005296|3219530:3226156|3224003_3225302_-|WP_011158399.1|DBSCAN-SWA
MASLAEKRIVEFEQPVEHLADDSAEQQPQSRPEELRLLEALLFASPEPLDQAALAKRMPEGVDVKVALKQLQEDYASRGVNLVRIANKWTFRTASDLAWLMTRESTETRKLSRAAIEMLAIIAYHQPITRVEIEEIRGVATSKGTLDVLLETGWVKPRGRRKTPGRPLTFGTTEAFLSQFSLESLTDLPGLEELKGTGLLDTRLPTGFSVPTPSDDPALREDEDPLEPGDLDLSLAPQPELDLEGDAAAADEAGVSATAEATGAAETGEAELGVAEAAAHDGAAPEVGFAETSEDDAEEAETGFAETSDDEAEAETGFAETEDADEAGEIEDAVEVGEVGDRELEAEEADADDFDIEDDVSIEIETVEVELVASDDQDEDVVAEAHEVASDDVEAGNDETGHTDTPELDTAEPEGSEEDAEHDAHGEDDQHQ
>NC_005296|3219530:3226156|3222894_3223431_-|WP_079403164.1|DBSCAN-SWA
MFDIGWSELMVIGVVALIAIGPKELPGVLRTVGQWMGKARRLATEFQGQFQEAMREAEMADLKKSFDEVKEATSGLSTNNMLTKLSSEVTDAMALDKATNIDTPPAEPTTPAQPTAETFVEATQHDAAASEPLAIVREAQGTEPPHLPVVAETHALATPDAAPPDLAHPEPTKDAKAS
>NC_005296|3219530:3226156|3223620_3223857_-|WP_011158398.1|DBSCAN-SWA
MGSLSIWHWIVVIAVVLLLFGRGKISDLMGDVAQGIKSFKKGLQDDEKTAEKSEPVKSIDHTSTPGATNRTDVGSKAV
>NC_005296|3219530:3226156|3222082_3222898_-|WP_011158396.1|DBSCAN-SWA
MSAEDIEASKAPLMDHLIELRSRLIKALLGFGIAFIFCFFFAKQIYNVLVWPFVWVAGPENSKFIYTALLEYFLTQLKLAMFGAGFISFPIIATQIYKFVAPGLYKHERNAFVPYLIATPGFFLLGSLVVYFLVLPMLVRFSLGMQQMGGAETAQIQLLPKVGEYLSLMMSLIFAFGLAFQLPVILTLLGRIGVLTAKQLKEKRRYFIVGAFIIAAVLTPPDVISQASLAIPLLLLYEGSIIAVSMVEKKRAAADASASANASTDSSTPAA
>NC_005296|3219530:3226156|3225322_3226156_-|WP_011158400.1|DBSCAN-SWA
MTAEILQFETGRPVEQQADQDEALVIDVEGYEGPLDLLLTLARQQKVDLHKISILALADQYLLFIEEARKIRLELAADYLVMAAWLAFLKSRLLLPEPPAQEGPSAEDMANALANRLRRLEAIREAANRLMTRAQLNRDIFPRGQVEEIAEIKHPKFTATLYDLLSAYASQRQSRVLTTVHLAKRTVWSLSEARASLERLVGLAEDWSRLDEYLLRYMPDPTQRATVLASSFAAALELVREGEVELHQSGPLAPLYFRKRPPSPAMEAAALPDTPVG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011158393.1|3219530_3220202_-	CAP domain-containing protein	A0A0E3T7R5	Bacillus_phage	3.9e-06	32.7
WP_011158394.1|3220207_3221512_-|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.0e-100	47.3
WP_079403165.1|3221636_3222020_-	autotransporter domain-containing protein	NA	NA	NA	NA
WP_011158396.1|3222082_3222898_-	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	8.4e-56	48.0
WP_079403164.1|3222894_3223431_-	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_011158398.1|3223620_3223857_-	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	4.2e-08	63.6
WP_011158399.1|3224003_3225302_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	4.5e-43	51.2
WP_011158400.1|3225322_3226156_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.3e-31	34.7