CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_014810	Helicobacter felis ATCC 49179, complete genome	2 crisprs	c2c9_V-U4,cas14j,cas3	1	0	5	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_014810_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014810_1

21958-22044

TypeV

Consensus_repeat	Method
CAAACCCCCCAAGAAACCACCCC	CRISPRCasFinder

1 spacers

c2c9_V-U4,cas14j

The CRISPR arrays of NC_014810_1

>merge|NC_014810|1|21958-22044|CRISPRCasFinder
CAAACCCCCCAAGAAACCACCCCGCCCCCCAAAAAAGCAGAAGTTAAAACAGCCGCAAAACCCCCAAAAACCCCAAAAACCCCCCAA

>NC_014810|1|1|21958-22044|CRISPRCasFinder
CAAACCCCCCAAGAAACCACCCC	GCCCCCCAAAAAAGCAGAAGTTAAAACAGCCGCAAAACCCC
CAAAAACCCCAAAAACCCCCCAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_014810.2\|WP_013468513.1\|24919_25264_-\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_049776917.1\|25260_25584_-\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_041302647.1\|19770_20046_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378838
NC_014810.2\|WP_013468504.1\|20791_21304_+\|DUF1804-family-protein	unknown	unknown	gnl\|CDD\|370140
NC_014810.2\|WP_013468502.1\|17104_18244_+\|phage-head-morphogenesis-protein	unknown	unknown	gnl\|CDD\|309383
NC_014810.2\|WP_041302649.1\|23185_23419_-\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013468786.1\|20020_20671_-\|IS607-family-transposase	unknown	unknown	gnl\|CDD\|239738
NC_014810.2\|WP_158305091.1\|23417_23570_+\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013468507.1\|22823_23189_+\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013468499.1\|13443_13674_+\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013468506.1\|22147_22831_+\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013468512.1\|24486_24918_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|177282
NC_014810.2\|WP_013468510.1\|23892_24261_-\|holin	unknown	unknown	gnl\|CDD\|368287
NC_014810.2\|WP_013468519.1\|15217_16483_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NC_014810.2\|WP_013468501.1\|16622_17054_-\|phage-virion-morphogenesis-protein	unknown	unknown	gnl\|CDD\|368274
NC_014810.2\|WP_041302646.1\|18761_19751_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl\|CDD\|223747
NC_014810.2\|WP_013468511.1\|24253_24487_-\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_041302645.1\|18386_18767_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|177958
NC_014810.2\|WP_013468500.1\|13666_15196_+\|phage-terminase-large-subunit	unknown	unknown	gnl\|CDD\|130691
NC_014810.2\|WP_013468509.1\|23591_23906_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014810.2\|WP_041302647.1\|19770_20046_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378838	pfam12323, HTH_OrfB_IS605, Helix-turn-helix domain. This is the N terminal helix-turn-helix domain of Transposase_2 pfam01385.	2.25093e-12
NC_014810.2\|WP_013468504.1\|20791_21304_+\|DUF1804-family-protein	gnl\|CDD\|370140	pfam08822, DUF1804, Protein of unknown function (DUF1804). This family of bacterial protein is uncharacterized.	0.00194895
NC_014810.2\|WP_013468501.1\|16622_17054_-\|phage-virion-morphogenesis-protein	gnl\|CDD\|368274	pfam05069, Phage_tail_S, Phage virion morphogenesis family. Protein S of phage P2 is thought to be involved in tail completion and stable head joining.	2.99798e-05
NC_014810.2\|WP_013468502.1\|17104_18244_+\|phage-head-morphogenesis-protein	gnl\|CDD\|309383	pfam04233, Phage_Mu_F, Phage Mu protein F like protein. Members of this family are found in double-stranded DNA bacteriophages, and in some bacteria. A member of this family is required for viral head morphogenesis in bacteriophage SPP1. This family is possibly a minor head protein. This family may be related to the family TT_ORF1 (pfam02956).	7.64095e-08
NC_014810.2\|WP_041302646.1\|18761_19751_-\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.72552e-35
NC_014810.2\|WP_013468510.1\|23892_24261_-\|holin	gnl\|CDD\|368287	pfam05106, Phage_holin_3_1, Phage holin family (Lysis protein S). This family represents one of a large number of mutually dissimilar families of phage holins. Holins act against the host cell membrane to allow lytic enzymes of the phage to reach the bacterial cell wall. This family includes the product of the S gene of phage lambda.	0.000421298
NC_014810.2\|WP_013468786.1\|20020_20671_-\|IS607-family-transposase	gnl\|CDD\|239738	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.	1.59875e-61
NC_014810.2\|WP_013468519.1\|15217_16483_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.30056e-60
NC_014810.2\|WP_041302645.1\|18386_18767_+\|hypothetical-protein	gnl\|CDD\|177958	PLN02324, PLN02324, triacylglycerol lipase.	0.000506321
NC_014810.2\|WP_013468500.1\|13666_15196_+\|phage-terminase-large-subunit	gnl\|CDD\|130691	TIGR01630, psiM2_ORF9, phage uncharacterized protein (putative large terminase), C-terminal domain. This model represents the C-terminal region of a set of phage proteins typically about 400-500 amino acids in length, although some members are considerably shorter. An article on Methanobacterium phage Psi-M2 ( calls the member from that phage, ORF9, a putative large terminase subunit, and ORF8 a candidate terminase small subunit. Most proteins in this family have an apparent P-loop nucleotide-binding sequence toward the N-terminus. [Mobile and extrachromosomal element functions, Prophage functions].	5.94746e-07
NC_014810.2\|WP_013468512.1\|24486_24918_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|177282	PHA00447, PHA00447, lysozyme.	7.05465e-46

>NC_014810.2|WP_013468504.1|20791_21304_+|DUF1804-family-protein
MKKALHNLVGTRNNILLAENIRTLYLQGKSYEYICQTLNITKNTINSHRKRALKEGDDWDALLLIHKRNKQHIGMSEAYFVNALIAGFEAQILHNEQLSLPELAKYTKLYFQLKAPKNNDELRAKELAHANTQRVLRVIAKLAMDMQAEEVVEFLSAHADAIIKEVFKKD
>NC_014810.2|WP_013468786.1|20020_20671_-|IS607-family-transposase
MNNLLSIGQASKVLGVSIQTLRNWEKKGLLKPDNYTKGGERRYKLESLKNINKNIVFHNDNRKTIAYARVSSADQKEDLIRQVQVLELYCSKLGFNYEVIQDLGSGMNYYKKGLTKLLNLILESQVKRLVLTHKDRLLRFGAELVFAICEAKEVEVIVINQGDENVRFEEELAKDVLEIITVFSARLYGARSKKNKQLLEQMQAVVENNVTTDPQD
>NC_014810.2|WP_041302647.1|19770_20046_-|helix-turn-helix-domain-containing-protein
MLQLTHKIELSPNNHAKTHFKKAMGCARLAYNWGLAKWRENYEKGIKSNHFALKKEFNALKKTNYPFVYEVTKYATAQPFTHLNLSISKIL
>NC_014810.2|WP_041302646.1|18761_19751_-|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MSYPRFKRKREYQGSFYIGGDQVKIIQGDKKDYLKIPNLPKIKMTEKLRFKGKINGATITQRGNKFYVSIQIDITQEEFNRTHKPIANNHTLGIDTGIKAFASLSNGLQIQAPKPLNRLTRRLKRLSRQLSKKRHSKTKNDGVKKSRNYLKASLRLNRLHTKIANTRNDFLHKLSTALVRHAKTLCMESLKVKNMLKNSKLAKALSDVSISAFNTLLEYKAKCYGQEILRADVFYPSSKTCSSCGSLKKDLTLSDRVYKCGVCGAVVDRDFNASVNLVKHLVSGVPTEFTPADMTALLSDFAKNGLVTSMVETGIQQKPLKFFSIDRIL
>NC_014810.2|WP_041302645.1|18386_18767_+|hypothetical-protein
MKKVKIGEHFKQAPGLKEGWKLQKLHFEQLKKRPAHEESYPFAQRVLAILKSAVDVLPLDPKQGRHVGSGYIEGRSLYDKAPTIEQIRGWVKDSLEIRLNKDQSAWDGHGIIYHRSYKPIKPHKIL
>NC_014810.2|WP_013468502.1|17104_18244_+|phage-head-morphogenesis-protein
MPYLESIAALMARKPALIKDPAKFKFEDHLRAFALAGVGSIDTIIDFQNALEKAIAHKQTLHDFIKANPNLAKEFSKKRLERIFSYNKVYSHTRARMLDYENTPPIAESEDGDGWYYLFESELDSAARHKAYHGVCLPRKHEFWKTHTPPLDWGCRCRLSMHSKEGLKRYNRLNDTRYQISTSPPPSVRSAKEKNAFESDVYKFLHNFFNAKLQRYAGNKEAVARLANVVRVCEAKKLRFKKLLELSKSPEQMIDFATLKPEVMQVVGAHSPLVRLSARTLTTHLEKHPETDLFDYYLAQDILQEPMAIFKDKQGSSAPGALNNYLIGVKFGRWYRLSIGVEQGENRFRSLVHGSKVRLIKKLMGAKQLIYKSKDFTLE
>NC_014810.2|WP_013468501.1|16622_17054_-|phage-virion-morphogenesis-protein
MIDLSTILTEVKLAIENHTEHAFRVQKDPVSGASWSPLKPASLKVKRPNMRAKILQNTRAMRSGVHVQIEGNKVVTQIDQSNAEKYAPFHQLGTSKMPQRRFLPFGDQGVPSEALQRDIQEILTTGRGGEDLKRQIQEMLRGS
>NC_014810.2|WP_013468519.1|15217_16483_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MLKAIKFRIYPSVEQKTLIHKHFGCARVIYNYFLAYRQKQYALGIKENYFSMQKVLTTLKKQESYAYLSECNSQSLQMALRQLTTAFDKFFSKLADYPRFKSKKHSKQSFCVPQHLRVDLGNNQVKLPKFKEAIKAKFHRHLPTNSIVKQGFISCVADKYYLSVSYEDNKPEPKPTTIRKAVGLDMGLESLVIASNGVFYPYKKFFQNLQTKLTKAQRRLSKKLKGSSNRKKQAKKVAQIHASIRNSREDYLHKISSEITNQYDLIAVETLKVRNLVKNHKLAKSIANASWSRLISLLEYKAGWKGKTLIKIDQYFPSSQICCTCGSNTGKKPLRIRNFVCPCCQTHHHRDLNASINIRNYALGMLDERHAIKVDKTRVGITRSYACGDSANGAVTKYGYILDTASYGSLKQEAHPSLAGG
>NC_014810.2|WP_013468500.1|13666_15196_+|phage-terminase-large-subunit
MNESFEDLKQYLKSLKSAFNADPKRKSAALKHFGVFAQTYFSHHLEKGDHSHFRESIYNHIKTYLDDSKICIFKAYRGAYKTTLLARMLTIWLFARNERHYMIYIGNKKEDTEETIEWLKIELTENALLRQDFQIQKGYSWRKGELAIDFEGVHKKIKSYSIEENIRGLNFLGKRPDLIICDDMENGQRIQSKKYREDIYKQFESAILKLPARKGDYNILVVGTTLHEECLLLRLEQRWNAKSYSFPLVLDFGPHIDGLSAQNIHNYDLSKVILDDPSLDKKEVLMEFLGNKNAFLAEFQNTPTNAKDAILGDFELYTQLPPQIDAIYMGIDPALGKAKGDFFAIALVHYSKAQRRYFARVHAYKEKPDKMINIVLNTYAHALSLSPYVKIGIEVVAFQAFFKDQLKKRAQELGLHFFRPIELKNTTHKEIRIDSLAPLLSERVLLIDAYSHELIAELQSYPKSAHDDCLDALEFAMRIARHKNILDYVHVRKSLAKRRFKTLHKIMLQ
>NC_014810.2|WP_013468499.1|13443_13674_+|hypothetical-protein
MVMPLESDDEEVLELFNAFLLVHSFKIQGMSSFVDVELNYSALKDFCQKHHYDTLEIFELFKSASLVVSSCFLDHE
>NC_014810.2|WP_013468506.1|22147_22831_+|hypothetical-protein
MRLEEAINLKERIEARIAKLEKMLGRVKKLIGALTPLTPEQEKAKAEQALFEQIMQADRISPEDLKALRVKFEPFEEFEGDFSDGSITSAPFLQYFKKLPPLDQQALLSASLKGLCLQVSKEVLDFQAASLLTQLYYAPQIALLALEDQDLAHLQILSAFMGEYGEITPQIAASMGGYEELRARYAQELHAFNDTWRLSPEEVAKHLQNWLNDPSLEAQVKQEVPND
>NC_014810.2|WP_013468507.1|22823_23189_+|hypothetical-protein
MTDTQKIQLRAKMLQSSPTVQKLHQVLGASIEVEQGGKPIVYLDALLSKLVCSAFTLHYLRTFSLEGLEMMPILEEIPLQYGGPAELPDNAQVKAFLSSVFERLKALNLQEFNLSKLELKR
>NC_014810.2|WP_041302649.1|23185_23419_-|hypothetical-protein
MGSPPLGGTFWLLICIIFFNGCYRVYKPVYIPTKCQIPKLERPALGSSSLAQNIKALLIYTELLEKDLEFCRVGKSH
>NC_014810.2|WP_158305091.1|23417_23570_+|hypothetical-protein
MLSFFELEDDLKPKYRDFKAECPHRITIMVAHDRSFLPGVGIGFPGIAIL
>NC_014810.2|WP_013468509.1|23591_23906_-|hypothetical-protein
MPSLKLTPLVVSVLGAMLCLAGLVYAGMWLRSLFVESETCKMGLEAQNKAILEQNIDVNNYVTRLQEQKDAITKRYEHVRALDSTCEHELKAIKRSLDVFRGGE
>NC_014810.2|WP_013468510.1|23892_24261_-|holin
MNKQDFLILGVEFRVILPYVLVLFVGFCVGWLFVLKSIKDEALSGLGDRLRYIIWGVGSSMLTTWVSFEVIGYYFHLPLGLATAISGGVGYMGAEVVGEMGLKMIRKKLGLHKEEEGKNAKP
>NC_014810.2|WP_013468511.1|24253_24487_-|hypothetical-protein
MAQETKQCGQIPLSRLDRMTRIGFLLILLNAIQTGFLAFLVYEIEDTQDHLSKSLEKVQKLEQRLDSLQSKIRRHFE
>NC_014810.2|WP_013468512.1|24486_24918_-|N-acetylmuramoyl-L-alanine-amidase
MAKTHQNIERIVIHCSDTPEGREHNAKDIERWHKERGFVRIGYHYVIKLDGSIEKGRADHEIGAHAKGYNTGSLGICYIGGRSKEGKAKDTRTPEQKQALKKLCAELAGKHPEADFCGHRDLDKGKECPCFDVKSFIKESGIV
>NC_014810.2|WP_013468513.1|24919_25264_-|hypothetical-protein
MSILRRACQILAQVFPDAHFILDSNTIQNPGLFVIIEGVERLDIQSVRLPCSLYCAFLGVGNQLWENLDPILDFFHSNPSFLEGRFDFYKMSLQEVKEHLSLAHVQFSLRLFKE
>NC_014810.2|WP_049776917.1|25260_25584_-|hypothetical-protein
MRYSDFMQEFNLEDLRTRALSLLLNPELISDSMLSWAYTESLEFCAGRKAPIYALYDFALMRLKRLLKMPFSDEDALIYENARKAIERAPLLEGPAKRFVRTRDFGL

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Click the colored protein region to show detailed information

Crispr_ID: NC_014810_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014810_2

1593567-1593837

Orphan

Consensus_repeat	Method
CACTCCCCTTATCCGCCGCTTTTTGGTAATATTTCAACGCCTGTTGGTAGTCCTGAGGC	PILER-CR

2 spacers

The CRISPR arrays of NC_014810_2

>merge|NC_014810|2|1593567-1593837|PILER-CR
CCCCCATTTCCCCGGCTTTTTGGTAATATTTCAACGCCTGTTGGTAGTCCTGAGGCACACCTTGGCCATTTTTGTACATGAAAGCCAAGCTATTATATGCCCGCACACTCCCCTTATCCGCCGCTTTTTGGTAATATTTCAACGCCTGTTGGTAGTCCTGAGGCACACCTTGCCATTTTTGTACATGAAAGCCAAGCTATTATATGCCCGCACACTCCCCTTATCCGCCGCTTTTTGGTAATATTTCAACGCCTGTTGGTAGTCCTGAGGC

>NC_014810|2|1|1593567-1593837|PILER-CR
CCCCCATTTCCCCGGCTTTTTGGTAATATTTCAACGCCTGTTGGTAGTCCTGAGGCACA	CCTTGGCCATTTTTGTACATGAAAGCCAAGCTATTATATGCCCGCACACTCC
CCTTATCCGCCGCTTTTTGGTAATATTTCAACGCCTGTTGGTAGTCCTGAGGCACACCT	TGCCATTTTTGTACATGAAAGCCAAGCTATTATATGCCCGCACACTCC
CCTTATCCGCCGCTTTTTGGTAATATTTCAACGCCTGTTGGTAGTCCTGAGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014810.2\|WP_049776978.1\|1606618_1607701_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NC_014810.2\|WP_013470053.1\|1588747_1589008_-\|ribbon-helix-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374794
NC_014810.2\|WP_148230008.1\|1603115_1604513_-\|DUF4135-domain-containing-protein	unknown	unknown	gnl\|CDD\|271200
NC_014810.2\|WP_013470055.1\|1590347_1591388_-\|SEL1-like-repeat-protein	unknown	unknown	gnl\|CDD\|276807
NC_014810.2\|WP_158305102.1\|1594095_1596357_-\|SEL1-like-repeat-protein	unknown	unknown	gnl\|CDD\|223861
NC_014810.2\|WP_013470048.1\|1580134_1581811_+\|sulfatase-like-hydrolase/transferase	unknown	unknown	gnl\|CDD\|293741
NC_014810.2\|WP_013470063.1\|1601361_1603128_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_014810.2\|WP_013470054.1\|1589000_1589576_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224113
NC_014810.2\|WP_013470060.1\|1598375_1598735_+\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013470066.1\|1608204_1610121_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378817
NC_014810.2\|WP_013470059.1\|1596343_1598029_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NC_014810.2\|WP_041302924.1\|1611074_1612157_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NC_014810.2\|WP_013470052.1\|1586996_1588445_-\|glutamate-decarboxylase	unknown	unknown	gnl\|CDD\|130848
NC_014810.2\|WP_013470056.1\|1591357_1592041_-\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|276807
NC_014810.2\|WP_013470047.1\|1579036_1579888_-\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|276807
NC_014810.2\|WP_158305103.1\|1607945_1608110_-\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013470051.1\|1586143_1586761_-\|outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|280099
NC_014810.2\|WP_148229953.1\|1584196_1586083_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|280099
NC_014810.2\|WP_148229955.1\|1610430_1611162_-\|hypothetical-protein	unknown	unknown	unknown
NC_014810.2\|WP_013470049.1\|1581864_1583985_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599

Protein	Function_ID	Function_description	E-value
NC_014810.2\|WP_049776978.1\|1606618_1607701_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	1.31898e-28
NC_014810.2\|WP_013470053.1\|1588747_1589008_-\|ribbon-helix-helix-domain-containing-protein	gnl\|CDD\|374794	pfam16777, RHH_7, Transcriptional regulator, RHH-like, CopG. RHH_7 is a ribbon-helix-helix protein family expressed by Helicobacter species. These proteins bind to specific DNA sequences with high affinity and usually act as repressors. Many are putatively named CopG.	1.57056e-27
NC_014810.2\|WP_148230008.1\|1603115_1604513_-\|DUF4135-domain-containing-protein	gnl\|CDD\|271200	cd04792, LanM-like, Cyclases involved in the biosynthesis of class II lantibiotics, and similar proteins. LanM-like proteins. LanM is a bifunctional enzyme, involved in the synthesis of class II lantibiotics. It is responsible for both the dehydration and the cyclization of the precursor-peptide during lantibiotic synthesis. The C-terminal domain shows similarity to LanC, the cyclase component of the lan operon, but the N terminus seems to be unrelated to the dehydratase, LanB.	4.33542e-38
NC_014810.2\|WP_013470055.1\|1590347_1591388_-\|SEL1-like-repeat-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	9.85137e-38
NC_014810.2\|WP_158305102.1\|1594095_1596357_-\|SEL1-like-repeat-protein	gnl\|CDD\|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	7.25869e-41
NC_014810.2\|WP_013470048.1\|1580134_1581811_+\|sulfatase-like-hydrolase/transferase	gnl\|CDD\|293741	cd16017, LptA, Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase. Lipooligosaccharide Phosphoethanolamine Transferase A (LptA) or Lipid A Phosphoethanolamine Transferase catalyzes the modification of the lipid A headgroups by phosphoethanolamine (PEA) or 4-amino-arabinose residues. Lipopolysaccharides, also called endotoxins, protect bacterial pathogens from antimicrobial peptides and have roles in virulence. The PEA modified lipid A increases resistance to the cationic cyclic polypeptide antibiotic, polymyxin. Lipid A PEA transferases usually consist of a transmembrane domain anchoring the enzyme to the periplasmic face of the cytoplasmic membrane.	9.03215e-81
NC_014810.2\|WP_013470063.1\|1601361_1603128_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.4505e-66
NC_014810.2\|WP_013470054.1\|1589000_1589576_-\|hypothetical-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	0.000296283
NC_014810.2\|WP_013470066.1\|1608204_1610121_-\|hypothetical-protein	gnl\|CDD\|378817	pfam12128, DUF3584, Protein of unknown function (DUF3584). This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.	5.68131e-06
NC_014810.2\|WP_013470059.1\|1596343_1598029_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	1.24469e-29
NC_014810.2\|WP_013470052.1\|1586996_1588445_-\|glutamate-decarboxylase	gnl\|CDD\|130848	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha., glutamate decarboxylase. This model represents the pyridoxal phosphate-dependent glutamate (alpha) decarboxylase found in bacteria (low and hi-GC gram positive, proteobacteria and cyanobacteria), plants, fungi and at least one archaon (Methanosarcina). The product of the enzyme is gamma-aminobutyrate (GABA).	0
NC_014810.2\|WP_013470056.1\|1591357_1592041_-\|sel1-repeat-family-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	3.58856e-36
NC_014810.2\|WP_013470047.1\|1579036_1579888_-\|sel1-repeat-family-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	9.58551e-07
NC_014810.2\|WP_041302924.1\|1611074_1612157_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	4.78629e-30
NC_014810.2\|WP_013470051.1\|1586143_1586761_-\|outer-membrane-beta-barrel-protein	gnl\|CDD\|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	5.18691e-21
NC_014810.2\|WP_148229953.1\|1584196_1586083_+\|hypothetical-protein	gnl\|CDD\|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	0.00020028
NC_014810.2\|WP_013470049.1\|1581864_1583985_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	6.42232e-38

>NC_014810.2|WP_013470056.1|1591357_1592041_-|sel1-repeat-family-protein
MAVVGLNRISRVALVACVLCSAGLLQAKDKKAEQLKQQSKQELQAKQYFDAGAQAYDKKQYKKAVDLFQKAAMMGNSKAYAYLSKMESQGQGVPKNWKEKIEDYYKKTGQKGNNASYEKLGDMYAEGKGVPRDYKKAIDYYQKAAEQGSAEAYNKLGMMYFEGRGMPRNYTKAFDYYQKAAGMGDAKAYNNLGLMYYNGKGVRQDYQQALEYYKKPVRWGVLMGMPI
>NC_014810.2|WP_013470055.1|1590347_1591388_-|SEL1-like-repeat-protein
MGSADGYAHLGDLYYNGKGVSRDYTKAFEYYKKAGEMGSALSYYKLGAMYYSGRGMQQDYQEAVDYYKKAGQMESPDGYVHLGDIYYSGKGVPKDYTQALSYYKKAGEMGDGVAYERLGDIYVEGQSVPRDYAKAMDYYTKAAQNGDVDGYYKVGSLYYNGQGVPQDYAKAIDYYKKAAEEGSAVSYYSLGVMYRNGQGVPIDFQKAFGYYKQAAKMGSAKAYVGLGDLYSVEGGAPGGVPRDYKKAVEYYLKAGAMGDGVAYRILGDMYISGGSPVEGGLPKDDRKAAEYYQKAGEMGESSAYAMLGDMYQDGQGVPRDLDRAKEYYKKACDMGYQDTCSPSSEF
>NC_014810.2|WP_013470054.1|1589000_1589576_-|hypothetical-protein
MIFSTINKKGGVGKTAFSFSIAKDLKLFLQSNDNSIIESLYPNKTKISAHPSLLQDCVYDFGGFIERGVLDIARNSDAILIPCTPLYNAVLRTIESIQELQGIAVPLIVLITDFQSQKEKEQVVSTLQSNFTDLHFFFFKHSRILENSMRTGLSFKELAMQTPLAKLQYKTFIDEYQCLLETLQSKGKQHG
>NC_014810.2|WP_013470053.1|1588747_1589008_-|ribbon-helix-helix-domain-containing-protein
MDKKIPNSIQEALNNKAIQENTFAKKDKAKPGRKSIPEHLKQKFVVSFYLSKEEYTILENLANQEADSVGFFIKRYVLKNLVHGKG
>NC_014810.2|WP_013470052.1|1586996_1588445_-|glutamate-decarboxylase
MLHTKSHIQRDNEKFVFKADNSSTPIFGSAESDVLLPRDKIGKNMMDPRIAYQLVSDEMMHDGNPRYNLCTFVQTYMEEEARKIMLDSMATNAIDKSEYPQTTEIEKRCVNIIANLWNANHAEDFMGTSTVGSSEACMLGGMAMKFRWRKRAQALGIDISKQKPNLIVSSGYQVVWEKFCVYWDVELREVPMSDFNNLTLDPKEAIKLCDDYTIGIVPIMGITYTGGFDDIVTLDRLLSEYNQKAKISVSIHVDAASGGLYLPFINPDLTWDFRLKNVVSISTSGHKYGLIYPGIGWVMWRDKQFLPDELIFKVAYLGDFEPTFQINFSRSGSQIWAQYYCFVRWGFEGYKAVHAKTRDVGLFLARGIKSLGLFDMINEGQNIPIICWTMNTKAQKEKQWNLYDLADRLRFNGWQVPAYPLPANFQNVSVMRIVVRADQSMEQMSLFLKDLKQAIRELDTANLVSHKHPSESDDVVPVGYTH
>NC_014810.2|WP_013470051.1|1586143_1586761_-|outer-membrane-beta-barrel-protein
MAFKIQAKSLAFLTLMAMGTPQIAQADEKSGLFIGLGYQQGKGGGGEYKKALSSGFPLYGLDAQVGGIGFVNKWFGGQVYGFFDWNNSGFFDNWRIWEQFGKSGGGKWDVYTYGGAADMIVNLIATDTLALGLVGGVQLAGNTWSYNNFSHSGFQFLFNAGGRVRLTEHVAFQAGIKFPMIPQKITAKIKDIRRYVWYVNLNYIF
>NC_014810.2|WP_148229953.1|1584196_1586083_+|hypothetical-protein
MLQLKRFLFMFFVLSAVSADVRDGFFIGGQLDLKNASPSYEMSQKNASSSSNTEVKAFALQQQLNTNIDKLTTNLNNAAIKALENVLKDSKVAYQIQNNQVSITTNINDLSPLSSFLGKLESQDNALEQAIAQEIEALNAMIANKQIPDTSKVQQASAEYANILKTLQEGSKNLAHEVDDMINDYNKALANAKTVYKDALQKHQTTQQENIQYQKEEQKYNQEKQQYDTASGVVNNYNQILGDLINNIKKDALQFNNQGNPITKVVSWSAFLNNLTSINNNFNTINAMISANKEILKNVPWDSQTFSQYQQRGYNVAGQCGAGTQVSLSLQDFITCIENSMPNLDGILPTTQYQLVEIQSWFYQEAIQISMLGGGSNQNILDTKASLISAYECYLHILSASPPIPPRAQNPYADPTPPTPVPPVSPLPSPNFNYRFNFAKIASLSTPQFATRPNFSNMTRAFNNAFYHNINITGSLMAGYQRFFSRHFGFSLNASLGYGYMHSPTYNNLSFFKRLQDVQMDLGGNLIYDFNMPKDDRSHLFYGVFAGLEGGFTEFILGAGNKNLWRTSYNLDVDLGLRFQFSTNIIKWGVDIPLMPHDINWQIGSTHLQLDESAKDMGIFITYEKLIF
>NC_014810.2|WP_013470049.1|1581864_1583985_-|methyl-accepting-chemotaxis-protein
MNLSSLRIGTKLVSLIIGVLLVIFIILSLVITYKSSETLQTEAYKTLYNVAKRHANRITPAFNQGFALLETLKATIQTSIAHNSLREDELISFIRTAFDEASWSDYCFLYLPRAAFKDRGDQAIPGFKDVGYLNKKEGFYLALKDTDVSQVGGIAPLSIEQSSGFFNDPNVKEAMLANKNTLSEPMRVNIAGDDVTSVIATVPIQDKQNRAVGFISFSINLAKMRQEIILEKTSSVYQGDIIAVVSSTGRVAAFPNTNMIGKSLLEVNPGPLTEAILKIVKEHKEGVFPYINIRHEQSFIGLVNFKVWRDIDQFWSVFIVAPKHSIFKPKEELTKLVITTAFLSLIIAGICVALLANKIISARLSVVLEGLISFFRFLNHEKISLKPLKIQSNDELGQMVSAINTNIQKIQVSLEEDEQAVSQSVNTAKIIESGDLSARITQIPANPQLKELKNVLNTMLDALERKVGSNINAINAVFEAYKQFDFTAEIQNAKGTVETTTNMLGQDIRQMLNASFAFAKELSSQSAVLKESMQTLSQSSVSQSNSLEGTARQIVQITASMQSTSAQTTEISKQAQEIKNIIGIIQDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTGKSLGEIEANANALIQSIDGIVSNIQEQTMGIERVNETVEQLEIVVQENAQIALDTDQITQKVNDIAKEIFDDVKKKKF
>NC_014810.2|WP_013470048.1|1580134_1581811_+|sulfatase-like-hydrolase/transferase
MVLDRRFWLMWLAPIVASFFSVDVQVWEGMFWHVLKVAFYSLLVFYVFYFLVEWIRFPKLVQFLKNTMLILSLSLNFIDFFASYYFHMGFTPSLVGTLLATNIRESREFLQSMVFPHMGFVLGYLAACAGFLYLVRFELILSIKQSLQTFLVLFVAFWAHNIGAFYLQKRHSFLINPNIPTRVIPVVKEIYAIVFHLKEYAQSKEIYSSLKKPYPKDYVHVDADSVSNVVLIVGESASRNFMGVYGYGVPNTPFLSALARDDAQNLFVFRDVISAFANTYSTFKTLLNYGDVENSATPWFLQKKLGRIFNLAGYQTFWIDAQDDLENNRSFALWSYPFTHRIWGNGPLDVPNATLDEWLVEAFNQRAKSKLASKNFILFHLFGSHATYTSRFPKDFAKFTPAQIPYRGLHVKNEQDKQIVADYVNSLYYTDHVLEEIFKLFKDKDAVIVYLSDHAQDIFESSDTYGHRCSDYGVEIPFVIYVSDLFKQKHPQKVQQLAQALNKPFMSDDLIHTLLPLAGIHTKDNLESKNLLSAKFDTRRKRVYCGNHVLKTQSPTAP
>NC_014810.2|WP_013470047.1|1579036_1579888_-|sel1-repeat-family-protein
MPFASLKNWGGGATLLASLFLFSACTTKIGSINPNQPTDPKMQSVYGVACKAFTWPYGNKDDDELKQQAMQQVNTQAQAYVTAANAKEAELANVNITKNIWPWFWGLMGQKCVEARGYAIPKGLSAQAQAQADAEKANKENNTTSCEGWKYVPDLESVITDSLDGEGGAPMVSPANAKNALEAFTRDSKSSDLHTKACALEGLGTLYYTGVGVKKNKRKAIELFEQEGKLGYGNGYRVLADMFRTKDIKKSEHYLELCKTTSHKPPHQPGEDGDSCQLTDLRG
>NC_014810.2|WP_158305102.1|1594095_1596357_-|SEL1-like-repeat-protein
MSCRIKICAQAYDKKQYKKAVDLFQKAAMMGNSKAYAYLEGVKQLSLNTAKDRFDVGDSNAQGGKVGVAQAYYNFGLLYYNGQGVYKNYAKAFQYFQAAGWNGSAQGYTRLGDMYYNGQGVRQDYQQALKYYNKAGAMGDGVAYRTLGDMYYNGQGVSKDEEQAVSYYTKAAKEGDVASYYNLGHMYQKGQGVPKDYMEALRFYKKASEMGNSKGYTRLGDLYYNGQGVPKDYAKAFDNYQKAAEKGSAEAYNKLGLMYYEGKGVPRDYKKALGYYQKAGEMGDFRGYIRLGDLYYNGQGVPKDYAKAFDNYQKAAEKGSAEAYNKLGLMYYEGKGVQQDYPQALEYYTKATKMGNANSYASLGTFYYDGQGAPRNYKKALEYYQKAGEMGSAKGYTRLGDLYYNGQGVPQNYQQALKYYNKAGAMGDGVAYRTLGDMYYNGQGVPQDYAKAIDYYKKAAENGDSVAYRILGDMYADGAKQAQVSHVEANIAPSAQEVVENTKPNPVEKIGEAQVDHGMDTKQHDKQQEDHVVQQDQTSPKNKNLENLEKMEKIEKENAQQYYSLGVMYRNGQGVPRDYKKAFTYYQKAGEMGDARAYNNIGTMYYNGQGVPQDYAKAIDYYKKAAEEGSAVSYYSLGVMYRNGQGVPRDYKKAFTYYQKAGEMGDARAYRVLGDMYISGGSPVEGGLPKDDGKAAKYYQKAGEMGESSAYAMLGDMYQDGQGVPKDLGKAKEYYKKACDMGYKDTCFSSSKL
>NC_014810.2|WP_013470059.1|1596343_1598029_+|replication-initiation-protein
MRQLNDLQALISVETDAVFKNALEQKQADCLKKLLELTKQVSTTPTSQIATPNQLKVIDTATQNTPNRQPATIESNTTNAEQQPLETQVITQPQPTIPHTISEKYVTFHNDVNSVSLGKLGTLETNLLFAIFNKLKDKQDELLVFDCDEIKTMVHAVKISKNELSGVVKRLWKNIRLANFWMLLPKRDESYMLFKTFAINYHDTKKTQIKSIEIQVNMPYFGYLLNFLNANFTSFELLEFQNIRSKYAKTLYRLLKQWRSTGVPPKKEWSEFRELMGISSNIKLIEVIERDILKPALKELSKLPHFENLCYKKLKTKGMGNRITHIQFYFQPVTKTSKDREQAEHDLRTIAWHIRSEKTIKQLQKQMKQKHKHDEAMKVLGLCFYKPEQPEIILAIDSVQPTPEGYEFLVKYYQDGQVFKERCAPAPNKEVLLEQIAQSGYQKLEIQTDYTLQQSSQPTLELQEHNGFKTLQGLIKPKKVQKPKQAQDLNSSNDLTEYIGRNLYMNTNGIPSSLKIKNISTLEDGQIQVEIKDIDKPRKALEPFSFKSAKHFENWFKKYEE
>NC_014810.2|WP_013470060.1|1598375_1598735_+|hypothetical-protein
MDNMDDLSVQPGVNMQARGAGQPHGGKVVNDKTAHNQVQPTRSQTQTPKGKSMKPLEEMTTRELGDKVARLSRQIVKAKTERDKAKRNLEVANAKIEKLKEQQKQASQMLMDKQAEDNK
>NC_014810.2|WP_013470063.1|1601361_1603128_-|ABC-transporter-ATP-binding-protein
MDRLVPLRTFSALCTSAPRLMVYALGLVLLTGAFPSLSVAITIKLVDLVALMLRHKNLEYKPLIEILSLGALVLFGSHVCAQALAHLQTLIAEKFSTCILSRLADKLETTADLSFLEDKERSVQINTLKNGLHIRPLNYVNNLFFNLQRLISLLSLFIVLGLMSWYLPFVMLLASAPSLLLSNHIARKHSQELDSLQDQKEALQSYLQHGLDSTKNKDNLLFNFIAAFKKDFTSKKTEYLKSFTQINQKQLIHSLFLNILVALFNASLLFLMIIVLLAKSVGVGAVAGYVQAFSMANQQLEDLVLFGRWFFVINTYFKNYFALLDAQDQAEKKQVLEEAITHIRFKEVCFSYQNKQVLHNINCAFSASKIYAIVGKNASGKSTLIKLLMGFYAPSSGEIIINHRYLLKDLNLKSYRHQLSAIFQDFSFYTGYSLENNIFMQTQPSPVQLATQERALNLLESTKELLAQFGKDIFGVQYNGQDFSGGQKQSLATLRAFLKESSCIILDEPSSAIDPIAQKDFLNFIFKMLDDKMAILITHHIISSKNVHEILVLEGGHLVERGDFNTLSNQKGLFARLYRESLRDGSKT
>NC_014810.2|WP_148230008.1|1603115_1604513_-|DUF4135-domain-containing-protein
MEFFLIPTIAKIIFDAKQSGGRDVYAMYFSNTKLLHEKLESFGILGRLCAHLRNFVLCTRSTLRRTLDALLHANLITCARDVVNVRVGLSDLHSLGFTSSLATTRDGQKFFVKQSIADPARIFYDMCDLLDVDVKKKEYVGNYHDLSITRFLPYEPNVKDARVFYRRMATLMALATALNLTDIHLENLLVHDQYPVILDFESLFTFKENQDLSDVESTLFVEQVSADFDGPIAKSFISALQGGAVRSKSFLHPFVVDDGSDNFRVSYRKLSNYESHNRIISGHRVVQPHHYLKTIISYFVKTMQGIRKNKLKILNLFSSVCLGSHRYRYILRPTAFYHFLFVRSHQPSEYMHLDAYWDKIRSKLDDVQVSHFCKSAKQEIIAYELEAIKNGLIPFFYRDSHTLNLYTIDSKVICHAFTQTLETNLVEKIHRISDRYIQENALIITKSLNKTGEIDQVARNAGWIV
>NC_014810.2|WP_049776978.1|1606618_1607701_+|replication-initiation-protein
MDVVEQKQILMRQLNDLQALISVETDAVFKNALEQKQADCLKKLLELTKQVSTTPTSQIATPNQLKVIDTATQNTPNRQPATIESNTTNAEQQPLETQVITQPQPTIPHTISEKYVTFHNDVNSVSLGKLGTLETNLLFAIFNKLKDKQDELLVFDCDEIKTMVHAVKISKNELSGVVKRLWKNIRLANFWMLLPKRDESYMLFKTFAINYHDTKKTQIKSIEIQVNMPYFGYLLNFLNANFTSFELLEFQNIRSKYAKTLYRLLKQWRSTGVPPKKECSEFRELMGISSNIKLIEVIERDILKPALKELSKLPHFENLCYKKLTTKGMGNRITHIQFYFQPVTKTSKDREQAEHDLFSH
>NC_014810.2|WP_158305103.1|1607945_1608110_-|hypothetical-protein
MQTQKDDLQREQDKLRTELINTQTQLNEQVAITTQLKADLEKSLANQKGKGRGI
>NC_014810.2|WP_013470066.1|1608204_1610121_-|hypothetical-protein
MGSIASINFKPTNNIQLHHNDRTIPPTYLLAKELGYGLGYGCECDRSGDDALALRHELITQAIERYRRTFNQPFKSRGVDKRISKVKRIEPRAYAQIMEQEKTRRKELERAHKEQLESLQANTENQQTELQALQQEKTTLEQTNTALTQENTELKNLNATQERTHQQTLTNKEQAYQQALELKNASIHALYHKNTTLSQENQTLKDNKTELETTLIDLVTIFVSQDKQDKKLTIKEAKPLLESVRKQMITINQGLGDLKLFTQEDYRALRALKDDGLSINGLKKRITQIEQEAKKRYEKLQEQYKDYLSPKQVEDKITATKALYEDYLSPSAVQELKQEHTKELESREQSHSKALQEKDIEHAQVLKEKDKTLEKVAQELKAKERQVQEHARDLADSNKALEKLTQELKAKDTEHTKELEALQTQHAKELEKARNEIDKDTKLQGYVGKVKDLLQKFVDQVINPMLEKLQTEKGAELKAVIQWKKDNEKEKAQYHAHLATLAYDLLAGKFPKINAIALLISRGGVKNAMNPEYFESIAKDRRDRFLNKHINEIEKSLNQELKPILAKIEQTREWEHKALLGGIRGLENGIAKLAEEFKNSDAYGQMLETAKGDAQYYKGKTLKLTTELEEKDKRIKNP
>NC_014810.2|WP_148229955.1|1610430_1611162_-|hypothetical-protein
MGNRITHIQFYFQPITKTKKEQEKAHHDLRTIAWHIRSEKTIKQLQQQMKQEHQHDETMEVLGLCFYKPEQPEIILAIDSIQPTPEGYEFLVKYYQDGQVFKERCAPAPNKEVLLKQIAQSGYQRLEIQTDYTLQQLSQPALELQEHNGFKTLQGLVKPKKTQKPKQTQALNSSNDLTEYIGRNLYMNTNGIPSNLKIKDVSTLESGHIQVEIKDVDKPRKALEPFSFKSVKHFENWFKKYEE
>NC_014810.2|WP_041302924.1|1611074_1612157_-|replication-initiation-protein
MDVVEQKQILMRQFNDLQALISIETDTAFRNALEQKQTDCLKKLTELAVQTARTHQFPDSAPPKKFLTPRTANQQPISTPSPATEITTQAPIQQQDPLETQLITQQQPTTHHAASEKYVTFHNDVNSVSLGKLGALETNLLFAIFNRLKDKQDELLVFEIDEIKAMIGAKTKVNINNLSKIVEKLWKNIRVANFWILYPRAKDGIMLFRRFRINYHDTKKTQVKSIEIQVNMPYFGYLLNFLNANFTSFELLEFQNIRSKYAKTLYRLLKQWRSTGVPPKKEWSEFRELMGISSNIKLIEVIERDILKPAIKELSKLPHFEHLCYKKLKQKAWAIVSPTFNSTSSQLLRLRKNKKKPTMI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_014810_2	2.1\|1593626\|52\|NC_014810\|PILER-CR	1593626-1593677	52	NC_014810.2	1569109-1569160	0	1.0
NC_014810_2	2.1\|1593626\|52\|NC_014810\|PILER-CR	1593626-1593677	52	NC_014810.2	1569217-1569268	1	0.981

1. spacer 2.1|1593626|52|NC_014810|PILER-CR matches to position: 1569109-1569160, mismatch: 0, identity: 1.0

ggcacaccttggccatttttgtacatgaaagccaagctattatatgcccgca	CRISPR spacer
ggcacaccttggccatttttgtacatgaaagccaagctattatatgcccgca	Protospacer
****************************************************

2. spacer 2.1|1593626|52|NC_014810|PILER-CR matches to position: 1569217-1569268, mismatch: 1, identity: 0.981

ggcacaccttggccatttttgtacatgaaagccaagctattatatgcccgca	CRISPR spacer
ggcacaccttgcccatttttgtacatgaaagccaagctattatatgcccgca	Protospacer
*********** ****************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3815 : 33757

Helicobacter_phage(50.0%)

terminase,head,holin,integrase,transposase

attL 3712:3771|attR 35385:35487

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3712:3771	attL	NA	NA	NA	NA
WP_041302643.1\|3815_5402_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_013468485.1\|5595_6465_+	AAA family ATPase	A0A0M3LP72	Mannheimia_phage	5.0e-30	32.7
WP_013468486.1\|6474_6795_+	hypothetical protein	NA	NA	NA	NA
WP_013468487.1\|6791_6968_+	hypothetical protein	NA	NA	NA	NA
WP_013468488.1\|7033_7285_+	hypothetical protein	NA	NA	NA	NA
WP_013468489.1\|7277_7700_+	host-nuclease inhibitor Gam family protein	NA	NA	NA	NA
WP_013468490.1\|7696_7969_+	hypothetical protein	NA	NA	NA	NA
WP_013468491.1\|8065_8992_+	hypothetical protein	NA	NA	NA	NA
WP_013468493.1\|9201_10329_+\|transposase	transposase	NA	NA	NA	NA
WP_013468494.1\|10401_10842_+	hypothetical protein	NA	NA	NA	NA
WP_013468495.1\|10917_11382_-	hypothetical protein	NA	NA	NA	NA
WP_013468496.1\|11458_12676_+	DUF935 family protein	NA	NA	NA	NA
WP_013468498.1\|13054_13411_+	hypothetical protein	NA	NA	NA	NA
WP_013468499.1\|13443_13674_+	hypothetical protein	NA	NA	NA	NA
WP_013468500.1\|13666_15196_+\|terminase	phage terminase large subunit	A0A0M3LQB7	Mannheimia_phage	6.7e-38	26.3
WP_013468519.1\|15217_16483_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5REX3	Helicobacter_phage	2.2e-127	55.4
WP_013468501.1\|16622_17054_-	phage virion morphogenesis protein	NA	NA	NA	NA
WP_013468502.1\|17104_18244_+\|head	phage head morphogenesis protein	A0A2H4IYU7	uncultured_Caudovirales_phage	1.2e-07	28.9
WP_041302645.1\|18386_18767_+	hypothetical protein	NA	NA	NA	NA
WP_041302646.1\|18761_19751_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RGV0	Helicobacter_phage	7.7e-112	63.2
WP_041302647.1\|19770_20046_-	helix-turn-helix domain-containing protein	A0A1S5RGV0	Helicobacter_phage	3.2e-31	70.5
WP_013468786.1\|20020_20671_-\|transposase	IS607 family transposase	A0A1S5RGS9	Helicobacter_phage	4.0e-93	83.2
WP_013468504.1\|20791_21304_+	DUF1804 family protein	NA	NA	NA	NA
WP_013468505.1\|21366_22146_+	hypothetical protein	NA	NA	NA	NA
WP_013468506.1\|22147_22831_+	hypothetical protein	NA	NA	NA	NA
WP_013468507.1\|22823_23189_+	hypothetical protein	NA	NA	NA	NA
WP_041302649.1\|23185_23419_-	hypothetical protein	A0A1S5RG56	Helicobacter_phage	7.3e-05	42.2
WP_158305091.1\|23417_23570_+	hypothetical protein	NA	NA	NA	NA
WP_013468509.1\|23591_23906_-	hypothetical protein	NA	NA	NA	NA
WP_013468510.1\|23892_24261_-\|holin	holin	A0A1S5RFV1	Helicobacter_phage	2.5e-23	48.6
WP_013468511.1\|24253_24487_-	hypothetical protein	NA	NA	NA	NA
WP_013468512.1\|24486_24918_-	N-acetylmuramoyl-L-alanine amidase	A0A2K9VHF1	Pseudomonas_phage	5.0e-31	46.9
WP_013468513.1\|24919_25264_-	hypothetical protein	NA	NA	NA	NA
WP_049776917.1\|25260_25584_-	hypothetical protein	NA	NA	NA	NA
WP_013468515.1\|25606_26389_-	hypothetical protein	NA	NA	NA	NA
WP_013468516.1\|26388_27222_-	mu-like prophage i protein	A0A2P9JZJ0	Alteromonadaceae_phage	2.0e-12	32.0
WP_013468517.1\|27294_31257_+	hypothetical protein	X2KR41	Campylobacter_phage	4.9e-24	30.0
WP_013468518.1\|31308_32184_+\|head	Mu-like prophage major head subunit gpT family protein	H7BVL8	unidentified_phage	5.2e-43	35.1
WP_013468519.1\|32491_33757_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5REX3	Helicobacter_phage	2.2e-127	55.4
35385:35487	attR	NA	NA	NA	NA

DBSCAN-SWA_2

159692 : 165620

Acinetobacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013468647.1\|159692_160325_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.2e-20	43.7
WP_013468648.1\|160324_161368_-	ribonucleotide-diphosphate reductase subunit beta	A2PYN0	Cyanophage	2.3e-53	34.1
WP_041303027.1\|161418_162279_-	DNA glycosylase	G3CB03	Aeropyrum_pernix_spindle-shaped_virus	3.5e-12	32.6
WP_013468650.1\|162388_163180_-	glycosyltransferase family 25 protein	A0A1S5NQ44	Burkholderia_phage	2.8e-11	27.3
WP_013468651.1\|163258_164269_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.9e-41	33.8
WP_013468652.1\|164261_165620_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	1.1e-39	41.7

DBSCAN-SWA_3

627062 : 633990

Prochlorococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013469094.1\|627062_628487_+\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	5.1e-48	34.9
WP_013469095.1\|628495_628996_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	5.2e-24	42.6
WP_013469096.1\|628992_629703_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	E3SPA9	Prochlorococcus_phage	8.2e-39	38.4
WP_013469097.1\|629705_631109_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.0e-48	33.3
WP_013469098.1\|631118_632141_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.6e-67	43.0
WP_013469099.1\|632128_632833_+	IMP cyclohydrolase	NA	NA	NA	NA
WP_013469100.1\|632832_633990_+	phosphoribosylaminoimidazolecarboxamide formyltransferase	Q58MG4	Prochlorococcus_phage	2.2e-25	27.2

DBSCAN-SWA_4

1020487 : 1036233

Helicobacter_phage(72.73%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013469483.1\|1020487_1020991_+	hypothetical protein	A0A1S5RG08	Helicobacter_phage	3.8e-30	38.0
WP_013469484.1\|1020987_1021260_+	hypothetical protein	NA	NA	NA	NA
WP_013469485.1\|1021246_1021537_+\|holin	phage holin family protein	A0A1B0XWG7	Campylobacter_phage	5.2e-08	30.3
WP_013469486.1\|1021533_1021863_+	hypothetical protein	NA	NA	NA	NA
WP_148229940.1\|1021834_1022452_-	DUF1804 family protein	A0A1S5RFH0	Helicobacter_phage	1.4e-31	36.6
WP_013469488.1\|1022461_1022941_-	hypothetical protein	NA	NA	NA	NA
WP_013469489.1\|1022937_1023828_-	hypothetical protein	A0A1S5RG14	Helicobacter_phage	2.1e-44	45.3
WP_049776951.1\|1023827_1024793_-	hypothetical protein	A0A1S5RFN3	Helicobacter_phage	5.6e-14	33.6
WP_013469492.1\|1026449_1027160_-	hypothetical protein	A0A1D8KL30	Synechococcus_phage	2.4e-06	29.9
WP_013469493.1\|1027169_1027379_-	hypothetical protein	NA	NA	NA	NA
WP_041303250.1\|1027655_1028771_-\|transposase	transposase	G9CU70	Helicobacter_phage	3.9e-136	65.4
WP_013469496.1\|1029590_1031348_-	hypothetical protein	A0A1S5RGP0	Helicobacter_phage	3.3e-198	64.0
WP_041302824.1\|1031649_1031862_-	hypothetical protein	I6P014	Helicobacter_phage	7.3e-12	54.5
WP_041302826.1\|1031912_1032671_-	site-specific DNA-methyltransferase	Q775B4	Bordetella_phage	1.4e-52	44.5
WP_158305107.1\|1032804_1036233_-	hypothetical protein	A0A1S5RFG7	Helicobacter_phage	1.1e-96	30.6

DBSCAN-SWA_5

1562010 : 1571777

Helicobacter_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041303413.1\|1562010_1563606_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.6e-101	41.3
WP_013470039.1\|1564456_1565161_+	hypothetical protein	A0A1S5RH75	Helicobacter_phage	1.5e-93	68.6
WP_041302915.1\|1565729_1566278_+	hypothetical protein	NA	NA	NA	NA
WP_148229951.1\|1566342_1567155_+	hypothetical protein	A0A1S5RG15	Helicobacter_phage	6.1e-22	35.0
WP_148229952.1\|1567236_1568445_+	hypothetical protein	A0A1S5RG62	Helicobacter_phage	3.6e-71	41.7
WP_049776973.1\|1568422_1568650_+	hypothetical protein	NA	NA	NA	NA
WP_049776975.1\|1568640_1569015_+	hypothetical protein	A0A1S5REZ7	Helicobacter_phage	2.3e-16	49.5
WP_013470042.1\|1569077_1569695_-	sel1 repeat family protein	NA	NA	NA	NA
WP_081458377.1\|1569863_1571777_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.2e-13	33.2

Anti-CRISPR protein detection

Acr_ID: NC_014810.2|WP_013470042.1|1569077_1569695_-|sel1-repeat-family-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_014810.2|WP_013470042.1|1569077_1569695_-|sel1-repeat-family-protein

1569077_1569695_-

205 aa aa

1562010-1571777

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_014810_2	Orphan	2.1\|1593626\|52\|NC_014810\|PILER-CR	1593626-1593677	52	1569109-1569160	0
NC_014810_2	Orphan	2.1\|1593626\|52\|NC_014810\|PILER-CR	1593626-1593677	52	1569217-1569268	1

1. spacer 2.1|1593626|52|NC_014810|PILER-CR matches to NC_014810 position: 1569109-1569160, mismatch: 0

ggcacaccttggccatttttgtacatgaaagccaagctattatatgcccgca	CRISPR spacer
ggcacaccttggccatttttgtacatgaaagccaagctattatatgcccgca	Protospacer
****************************************************

2. spacer 2.1|1593626|52|NC_014810|PILER-CR matches to NC_014810 position: 1569217-1569268, mismatch: 1

ggcacaccttggccatttttgtacatgaaagccaagctattatatgcccgca	CRISPR spacer
ggcacaccttgcccatttttgtacatgaaagccaagctattatatgcccgca	Protospacer
*********** ****************************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014810

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information