CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_015418	Clostridium botulinum BKT015925 plasmid p3BKT015925, complete sequence	0 crisprs	NA	0	0	1
NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	4 crisprs	cas14j,c2c9_V-U4,cas8b1,cas7b,cas5,cas3,cas14k,csa3,RT	1	41	6
NC_015427	Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence	0 crisprs	NA	0	0	1
NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	4 crisprs	cas14j,cas3,cas6	0	45	1
NC_015419	Clostridium botulinum BKT015925 plasmid p5BKT015925, complete sequence	0 crisprs	NA	0	0	0
NC_015425	Clostridium botulinum BKT015925, complete sequence	1 crisprs	cas3,csa3,DEDDh,RT	0	0	7

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8054 : 59114

Bacillus_phage(20.0%)

transposase,integrase

attL 4601:4618|attR 29126:29143

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4601:4618	attL	NA	NA	NA	NA
WP_013720788.1\|8054_9287_+\|transposase	IS256-like element ISCbo4 family transposase	A0A218MNI5	uncultured_virus	2.3e-52	52.1
WP_013720975.1\|9911_10703_-	esterase	NA	NA	NA	NA
WP_013720976.1\|10997_12197_-	phospholipase C	NA	NA	NA	NA
WP_039240833.1\|12462_13197_+	AAA family ATPase	NA	NA	NA	NA
WP_013720978.1\|13459_14185_+	hypothetical protein	NA	NA	NA	NA
WP_013720979.1\|14320_14488_-	hypothetical protein	NA	NA	NA	NA
WP_013720980.1\|14582_15272_+	lantibiotic protection ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.9e-57	50.7
WP_158002115.1\|15299_16013_+	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	NA	NA	NA	NA
WP_013720982.1\|16016_16826_+	lantibiotic immunity ABC transporter MutG family permease subunit	NA	NA	NA	NA
WP_013720983.1\|16925_17618_+	response regulator transcription factor	W8CYM9	Bacillus_phage	6.5e-25	31.7
WP_013720984.1\|17607_19005_+	HAMP domain-containing histidine kinase	A0A1V0SGR3	Hokovirus	3.3e-07	24.5
WP_013720986.1\|19565_19808_-	type II toxin-antitoxin system Phd/YefM family antitoxin	E4ZFM1	Streptococcus_phage	9.9e-13	47.1
WP_013720987.1\|20051_20657_+\|integrase	site-specific integrase	D2XR58	Bacillus_phage	2.1e-35	46.0
WP_013720822.1\|21209_21905_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.2e-52	48.1
WP_043920880.1\|21925_23248_-\|transposase	IS21-like element ISCbo2 family transposase	A0A059NT83	Lactococcus_phage	2.7e-43	31.7
WP_013720989.1\|23555_24260_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	9.5e-48	48.7
WP_013720990.1\|24551_25106_+	hypothetical protein	NA	NA	NA	NA
WP_013720991.1\|25175_26180_-	tyrosine recombinase XerC	A0A2R2ZHE2	Clostridioides_phage	3.9e-18	29.0
WP_013720992.1\|26193_26853_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013720993.1\|27196_27538_-	hypothetical protein	NA	NA	NA	NA
WP_013720994.1\|27609_28113_-	hypothetical protein	NA	NA	NA	NA
WP_019278580.1\|28494_29430_-	hypothetical protein	NA	NA	NA	NA
29126:29143	attR	NA	NA	NA	NA
WP_013720996.1\|29819_30746_+	hypothetical protein	J7Q326	Aeropyrum_coil-shaped_virus	9.4e-11	30.2
WP_013720997.1\|30803_31187_-	hypothetical protein	NA	NA	NA	NA
WP_019278579.1\|31404_31707_-	Dabb family protein	NA	NA	NA	NA
WP_013720999.1\|31937_33233_+	hypothetical protein	NA	NA	NA	NA
WP_013721000.1\|33479_35657_+	hypothetical protein	A0A1V0E026	Clostridioides_phage	3.2e-118	41.3
WP_013721001.1\|35836_37201_+\|transposase	IS1182-like element ISCbo5 family transposase	A0A1X9I5T2	Streptococcus_phage	8.5e-77	38.4
WP_013721002.1\|37362_37851_-	hypothetical protein	NA	NA	NA	NA
WP_013721004.1\|39187_39493_-	hypothetical protein	NA	NA	NA	NA
WP_013721005.1\|39766_40195_+	hypothetical protein	NA	NA	NA	NA
WP_013721006.1\|40331_40673_+	hypothetical protein	NA	NA	NA	NA
WP_013721007.1\|41022_41937_+	hypothetical protein	NA	NA	NA	NA
WP_013721008.1\|42010_42421_-	hypothetical protein	NA	NA	NA	NA
WP_013721009.1\|42519_43002_-	hypothetical protein	NA	NA	NA	NA
WP_013721010.1\|43414_44665_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_013721011.1\|44692_45454_-	response regulator transcription factor	NA	NA	NA	NA
WP_013721012.1\|45563_46802_-	hypothetical protein	NA	NA	NA	NA
WP_013721013.1\|48521_49559_+\|transposase	IS6 family transposase	NA	NA	NA	NA
WP_013721014.1\|49836_50838_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013721015.1\|50838_51609_-	DUF3919 family protein	NA	NA	NA	NA
WP_013721016.1\|53006_53690_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.3e-33	35.8
WP_013721017.1\|53994_54783_+	ParA family protein	E2ELL2	Clostridium_phage	6.3e-24	35.3
WP_013721018.1\|54782_55241_+	hypothetical protein	NA	NA	NA	NA
WP_013721019.1\|55322_56426_-	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_013721022.1\|58079_59114_-\|transposase	IS6 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_015417

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015417_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015417_1

16802-18148

TypeV,TypeI-B

Consensus_repeat	Method
ATTAATAAATAACATAAGATGTTTTTAAAT	PILER-CR
ATTAATAAATAACATAAGATGTTTTTAAAT	CRISPRCasFinder
ATTAATAAATAACATAAGATGTTTTTAAAT	CRT

20 spacers

c2c9_V-U4,cas14j,cas8b1,cas7b,cas5,cas3

The CRISPR arrays of NC_015417_1

>merge|NC_015417|1|16802-18148|PILER-CR,CRISPRCasFinder,CRT
ATTAATAAATAACATAAGATGTTTTTAAATGCTTTGAAAGCTTGTCCCGAATAGCTTGTACACTTATATTAATAAATAACATAAGATGTTTTTAAATGAAACACAGTTTAAAACAAATTTGGAAGTTGGAATATTAATAAATAACATAAGATGTTTTTAAATAGCTAAAAAGAATGGTGAATACCTTCCTGAAATTAATTAATAAATAACATAAGATGTTTTTAAATGAATTAATAAAATTAATACAAGACAATACAATGGAAATTAATAAATAACATAAGATGTTTTTAAATAAATTTGCCATATGCGGTCCCCAAAGTACCCATTTACATTAATAAATAACATAAGATGTTTTTAAATAAACCTACATGATGATATATGGAAAGTAGAGCTTATATTAATAAATAACATAAGATGTTTTTAAATAAGTAAGCTTTTCCAGTAACTCCCCTTACTTTTAATATTAATAAATAACATAAGATGTTTTTAAATTTAGTGCCATAGTTTGTACTCCAAATATCTAAACATTAATAAATAACATAAGATGTTTTTAAATATAAAAATTTAAGATAAATTTAAGGGAAGACACTAATATTAATAAATAACATAAGATGTTTTTAAATTGAAGCAAGAAGAAAGAAGCGAATTTATAAAAGAGTATTAATAAATAACATAAGATGTTTTTAAATTTTGCTTGTCTTTGTTTTTCTCTAACATACTCCTGTATTAATAAATAACATAAGATGTTTTTAAATTCTATTAAAGATTTTAAAGCAAGATTTTCGCTTATATTAATAAATAACATAAGATGTTTTTAAATAGGTAAAGAACAAGACGATGAGGGATATTTTAGAGAATTAATAAATAACATAAGATGTTTTTAAATTTTGTAACTGTAAAATCATTTAACTTTTTAATATCTATTAATAAATAACATAAGATGTTTTTAAATTGTGATAGAGTAGCATTTAAATATAAGGTTCTAGGTATTAATAAATAACATAAGATGTTTTTAAATACATCTAATATAGTAATAGTCTTTTCTTTATCGTTATTAATAAATAACATAAGATGTTTTTAAATAGAATTACGAAGACAGTATGAGAATGCTAGAGAACTTATTAATAAATAACATAAGGTGTTTTTAAATTTTGACAAGCCTGTTTTTTATCCATTTTTGACATTATTAATAAATAATATAAGATGTTTTTAAATGAAATCGGTTGTCCTTTTGTATAATCTCTTAATCCAATTAATAAATAACATAAGATGTTTTTAAATTTTTGTTTTGTTCAGTATCTTTTTTTGGGAGTTCCTATTAATAAATAACATTATATGTTTTTAAAC

>NC_015417|1|1|16802-18082|PILER-CR
ATTAATAAATAACATAAGATGTTTTTAAAT	GCTTTGAAAGCTTGTCCCGAATAGCTTGTACACTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	GAAACACAGTTTAAAACAAATTTGGAAGTTGGAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGCTAAAAAGAATGGTGAATACCTTCCTGAAATTA
ATTAATAAATAACATAAGATGTTTTTAAAT	GAATTAATAAAATTAATACAAGACAATACAATGGAA
ATTAATAAATAACATAAGATGTTTTTAAAT	AAATTTGCCATATGCGGTCCCCAAAGTACCCATTTAC
ATTAATAAATAACATAAGATGTTTTTAAAT	AAACCTACATGATGATATATGGAAAGTAGAGCTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AAGTAAGCTTTTCCAGTAACTCCCCTTACTTTTAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	TTAGTGCCATAGTTTGTACTCCAAATATCTAAAC
ATTAATAAATAACATAAGATGTTTTTAAAT	ATAAAAATTTAAGATAAATTTAAGGGAAGACACTAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	TGAAGCAAGAAGAAAGAAGCGAATTTATAAAAGAGT
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTGCTTGTCTTTGTTTTTCTCTAACATACTCCTGT
ATTAATAAATAACATAAGATGTTTTTAAAT	TCTATTAAAGATTTTAAAGCAAGATTTTCGCTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGGTAAAGAACAAGACGATGAGGGATATTTTAGAGA
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTGTAACTGTAAAATCATTTAACTTTTTAATATCT
ATTAATAAATAACATAAGATGTTTTTAAAT	TGTGATAGAGTAGCATTTAAATATAAGGTTCTAGGT
ATTAATAAATAACATAAGATGTTTTTAAAT	ACATCTAATATAGTAATAGTCTTTTCTTTATCGTT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGAATTACGAAGACAGTATGAGAATGCTAGAGAACTT
ATTAATAAATAACATAAGGTGTTTTTAAAT	TTTGACAAGCCTGTTTTTTATCCATTTTTGACATT
ATTAATAAATAATATAAGATGTTTTTAAAT	GAAATCGGTTGTCCTTTTGTATAATCTCTTAATCCA
ATTAATAAATAACATAAGATGTTTTTAAAT

>NC_015417|1|1|16802-18148|CRISPRCasFinder
ATTAATAAATAACATAAGATGTTTTTAAAT	GCTTTGAAAGCTTGTCCCGAATAGCTTGTACACTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	GAAACACAGTTTAAAACAAATTTGGAAGTTGGAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGCTAAAAAGAATGGTGAATACCTTCCTGAAATTA
ATTAATAAATAACATAAGATGTTTTTAAAT	GAATTAATAAAATTAATACAAGACAATACAATGGAA
ATTAATAAATAACATAAGATGTTTTTAAAT	AAATTTGCCATATGCGGTCCCCAAAGTACCCATTTAC
ATTAATAAATAACATAAGATGTTTTTAAAT	AAACCTACATGATGATATATGGAAAGTAGAGCTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AAGTAAGCTTTTCCAGTAACTCCCCTTACTTTTAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	TTAGTGCCATAGTTTGTACTCCAAATATCTAAAC
ATTAATAAATAACATAAGATGTTTTTAAAT	ATAAAAATTTAAGATAAATTTAAGGGAAGACACTAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	TGAAGCAAGAAGAAAGAAGCGAATTTATAAAAGAGT
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTGCTTGTCTTTGTTTTTCTCTAACATACTCCTGT
ATTAATAAATAACATAAGATGTTTTTAAAT	TCTATTAAAGATTTTAAAGCAAGATTTTCGCTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGGTAAAGAACAAGACGATGAGGGATATTTTAGAGA
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTGTAACTGTAAAATCATTTAACTTTTTAATATCT
ATTAATAAATAACATAAGATGTTTTTAAAT	TGTGATAGAGTAGCATTTAAATATAAGGTTCTAGGT
ATTAATAAATAACATAAGATGTTTTTAAAT	ACATCTAATATAGTAATAGTCTTTTCTTTATCGTT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGAATTACGAAGACAGTATGAGAATGCTAGAGAACTT
ATTAATAAATAACATAAGGTGTTTTTAAAT	TTTGACAAGCCTGTTTTTTATCCATTTTTGACATT
ATTAATAAATAATATAAGATGTTTTTAAAT	GAAATCGGTTGTCCTTTTGTATAATCTCTTAATCCA
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTTGTTTTGTTCAGTATCTTTTTTTGGGAGTTCCT
ATTAATAAATAACATTATATGTTTTTAAAC

>NC_015417|1|1|16802-18148|CRT
ATTAATAAATAACATAAGATGTTTTTAAAT	GCTTTGAAAGCTTGTCCCGAATAGCTTGTACACTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	GAAACACAGTTTAAAACAAATTTGGAAGTTGGAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGCTAAAAAGAATGGTGAATACCTTCCTGAAATTA
ATTAATAAATAACATAAGATGTTTTTAAAT	GAATTAATAAAATTAATACAAGACAATACAATGGAA
ATTAATAAATAACATAAGATGTTTTTAAAT	AAATTTGCCATATGCGGTCCCCAAAGTACCCATTTAC
ATTAATAAATAACATAAGATGTTTTTAAAT	AAACCTACATGATGATATATGGAAAGTAGAGCTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AAGTAAGCTTTTCCAGTAACTCCCCTTACTTTTAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	TTAGTGCCATAGTTTGTACTCCAAATATCTAAAC
ATTAATAAATAACATAAGATGTTTTTAAAT	ATAAAAATTTAAGATAAATTTAAGGGAAGACACTAAT
ATTAATAAATAACATAAGATGTTTTTAAAT	TGAAGCAAGAAGAAAGAAGCGAATTTATAAAAGAGT
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTGCTTGTCTTTGTTTTTCTCTAACATACTCCTGT
ATTAATAAATAACATAAGATGTTTTTAAAT	TCTATTAAAGATTTTAAAGCAAGATTTTCGCTTAT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGGTAAAGAACAAGACGATGAGGGATATTTTAGAGA
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTGTAACTGTAAAATCATTTAACTTTTTAATATCT
ATTAATAAATAACATAAGATGTTTTTAAAT	TGTGATAGAGTAGCATTTAAATATAAGGTTCTAGGT
ATTAATAAATAACATAAGATGTTTTTAAAT	ACATCTAATATAGTAATAGTCTTTTCTTTATCGTT
ATTAATAAATAACATAAGATGTTTTTAAAT	AGAATTACGAAGACAGTATGAGAATGCTAGAGAACTT
ATTAATAAATAACATAAGGTGTTTTTAAAT	TTTGACAAGCCTGTTTTTTATCCATTTTTGACATT
ATTAATAAATAATATAAGATGTTTTTAAAT	GAAATCGGTTGTCCTTTTGTATAATCTCTTAATCCA
ATTAATAAATAACATAAGATGTTTTTAAAT	TTTTGTTTTGTTCAGTATCTTTTTTTGGGAGTTCCT
ATTAATAAATAACATTATATGTTTTTAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015417.1\|WP_013720779.1\|15734_16076_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720788.1\|25788_27021_-\|IS256-like-element-ISCbo4-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_015417.1\|WP_013720774.1\|11877_12573_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015417.1\|WP_013720768.1\|4399_5533_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NC_015417.1\|WP_039244073.1\|13705_14836_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl\|CDD\|223747
NC_015417.1\|WP_013720778.1\|14969_15656_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_015417.1\|WP_013720789.1\|27958_30445_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224124
NC_015417.1\|WP_019279139.1\|19012_19765_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720786.1\|22846_23980_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NC_015417.1\|WP_013720785.1\|22590_22749_-\|ribbon-helix-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|289422
NC_015417.1\|WP_013720776.1\|13448_13598_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369567
NC_015417.1\|WP_013720787.1\|24146_24860_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_015417.1\|WP_013720775.1\|12565_13000_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|197640
NC_015417.1\|WP_039244075.1\|18231_18456_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|379188
NC_015417.1\|WP_039244087.1\|21620_22553_+\|hypothetical-protein	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015417.1\|WP_013720781.1\|18614_18917_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720783.1\|19761_21618_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NC_015417.1\|WP_013720769.1\|6515_7640_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NC_015417.1\|WP_013720771.1\|7864_8314_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|214947
NC_015417.1\|WP_013720772.1\|9072_10782_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015417.1\|WP_013720788.1\|25788_27021_-\|IS256-like-element-ISCbo4-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.66787e-122
NC_015417.1\|WP_013720774.1\|11877_12573_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.21742e-76
NC_015417.1\|WP_013720768.1\|4399_5533_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.86479e-33
NC_015417.1\|WP_039244073.1\|13705_14836_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.16678e-33
NC_015417.1\|WP_013720778.1\|14969_15656_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.69546e-13
NC_015417.1\|WP_013720769.1\|6515_7640_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.76344e-54
NC_015417.1\|WP_013720786.1\|22846_23980_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.25547e-33
NC_015417.1\|WP_013720785.1\|22590_22749_-\|ribbon-helix-helix-domain-containing-protein	gnl\|CDD\|289422	pfam12651, RHH_3, Ribbon-helix-helix domain. This short bacterial protein contains a ribbon-helix-helix domain that is likely to be DNA-binding.	1.83724e-10
NC_015417.1\|WP_013720776.1\|13448_13598_-\|hypothetical-protein	gnl\|CDD\|369567	pfam07878, RHH_5, CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5. This family contains bacterial proteins that form a ribbon-helix-helix fold. This fold occurs in many examples of bacterial antitoxins.	0.00132098
NC_015417.1\|WP_013720775.1\|12565_13000_+\|sensor-histidine-kinase	gnl\|CDD\|197640	smart00304, HAMP, HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain.	2.08034e-05
NC_015417.1\|WP_039244075.1\|18231_18456_-\|alkaline-phosphatase	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	0.000243887
NC_015417.1\|WP_013720787.1\|24146_24860_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.64825e-28
NC_015417.1\|WP_013720789.1\|27958_30445_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.75234e-30
NC_015417.1\|WP_039244087.1\|21620_22553_+\|hypothetical-protein	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.90234e-17
NC_015417.1\|WP_013720771.1\|7864_8314_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|214947	smart00974, T5orf172, This entry represents the putative helicase A859L.	6.13487e-22

>NC_015417.1|WP_013720779.1|15734_16076_+|hypothetical-protein
MEEIIMALGYLLLLFIVMSAISSVGIVLLYVIKNETIKNILFYCLAMWSMGIACLAAISLPTNFLGHRLINCLLGFISIMAIILKIKDPQKPNIAYIIVTASTLLGMYSLFFS
>NC_015417.1|WP_013720778.1|14969_15656_+|HAMP-domain-containing-histidine-kinase
MNNTYRIYIFITFYKFYATDKLKREKENLIKSLSHDIRTPLTAIISYSDFIKNKRYNSNEKLESYIEIIQNKAYQIQELTNLLLNTDIKPPNSDNTPLLEGKLMFEQFISEFVSALEDENFEVEIDRLALVDFKAKFDVQDISRIFDNIYSNIIKYASNLGKIQLEIFIEDNNLVFTQTNVIKDKIPNNIESHGIGLNNINKIVKSYNGEMKYILTQKIYKIEIKIPL
>NC_015417.1|WP_039244073.1|13705_14836_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MIKAVKIRLFPTKEQEVLMFKSCGVARFTYNWGLNRWNEIYKSGEKPNKIKVRTEFNNTLKKDDNYKWLKEVSGQVTAKSFDDLKDGFDRFFKGLSGYPKFKTKKKSKKSFYVRYDSIKFKDHKVNFEKIGKVKYNTNYKIPNLSKYNNPRCHFDGKYWYLTLGFEHNENQVGLNKDLSIGIDLGVKDFAVVNCLDKPIKNINKSVKIRKLKKRLKRLQRQVSRKYLMNKQNNKFIKTNNIIKLEHEIRLIYRKLNNIRNNHIHQTTNKIIKLKPHRVVMEDLNIQGMMKNKHLSKAIQEQCFYEFIRQMKYKCEWNNIKFIQVDRFYPSSKTCSCCGNVKKDLKLSDRVYKCDKCGLVIDRDYNASINLSNYKIA
>NC_015417.1|WP_013720776.1|13448_13598_-|hypothetical-protein
MTISKDKTRTQITIEKDLKKQLEQVAKEQNRSFNNLVITILKDFMSKHS
>NC_015417.1|WP_013720775.1|12565_13000_+|sensor-histidine-kinase
MIKPYKIPKLALEFIGYLVISVIIAIFNFAFLYSISISFVKKLIEKGYYSPYTISDPKLIYWLKLSCILTALVIFFIFFIFFLGEKISYILYITKSIQILKSGNLTFRIESVGNNELSKLADTINSFSIALQNHMQNEVTNSYK
>NC_015417.1|WP_013720774.1|11877_12573_+|response-regulator-transcription-factor
MNLKTQNKILIADDDDDIRQILEILFTGEGYSVITAKNGNEAIEKVDDTLDIVILDVDMPEKSGFIASMEIRKKSFVPILFLTAYSQESDKTIGYSAGADDYVTKPFSHSELLLKVKALLRRYQIYQPQTKIQSSKIVIQGLTVDIETQTVLCDGKHIPLTHTEYKILELLITNRKRIFSINHIYNSVWQDDIVADSAVMVHIKNLRKKIENDTRNPKYIKTAWGKGYYID
>NC_015417.1|WP_013720772.1|9072_10782_+|hypothetical-protein
MGNMKKKIINENTTVVDNNIIESPLFISSKREITTLGTLESFCTNKNVQNVIEVMKEGFKKSPVPIDYRNAPVVYRKWVDSRGLERELLVTYEIPDMTTMDVWNALIGLYIQKMSPIQFDTTKSTYELDADEMEFTLYELAKFMNKSIGGSNLNTLTKEIIRLNNAKYYSFSNGVIFNKKKEKYIKSKTRGMSLIVDCSFESERKAKNEKFDSESKCKVQFNKLIIDNIRYQYIKYINPKEYFALPSKGITRRLYVYLKGNSHMSDGKKYTYIKRGLGMLRNKLPMYEHQPSKIKERLKSPLKNLIKNGMITDYFYGDEDIINEKERCIYFIFKGKKDDVINNLRKKYQEKQLQLEIALDEVREENKFEMKIPEDLDKALEGIGFNNKAINKLHAEYDKWHIIKYVIWLQYEQFKNNKVIQNSAGLLRFALMGNVNLDITNKDIVQFVENEKKKFEESKLSRQEILENAYDKYVDDEIEKFKKEDGGTIYDIVYQNTLINIETQLDSQIAQLKLLQKNEGVEMPSLKLWEEFKKKKDKSELFKKNFINSIKMFRGIKTLEEFEIEFDKK
>NC_015417.1|WP_013720771.1|7864_8314_+|GIY-YIG-nuclease-family-protein
MKELQTQLEALEKDKEDVYNREQNTRAGYVYVISNIGSFGENVYKIGMTRRLEPTDRVKELSGTSVPFSFDIHAMIFSEDAPKLESKLHEVFRNNEVNKINHRKEFFKVSLEEIEKIVKEEFDKPVEFTKLAQAEEYRQSLVLENTLTI
>NC_015417.1|WP_013720769.1|6515_7640_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MLKAFKYRIYPNDSQKIQLSKTFGCARFIYNYYLAKKIDLYKTDGKFISKYDCNSHCNKELKKSEQFKWLKDVDKFALTNSIYSLDSAYKKFFKEHSGFPKFKSKKIHNYSYTTNFTNNNIQADFMNNKIKLPKLKWIKCKLHRKFEGKIKSATISQVPSGKYFVSILVDVENIQLPKNNNQIAFDLGIKEFLIDSNNNHIDNPKTLYKYEQKLTKLQRQIAHKEKGSQNWIKQRIKIARLHEKITNIRKDFLNKLSCQITNDYGIIISEDLNIKNMVKNHHLAKSISDVSWGEFTRQLAYKSEWKGRIYHKIDPWFASSQLCSNCGYKNKEVRKLSVREWICSECGTIHQRDENASKNILKQGLKELELQIAI
>NC_015417.1|WP_013720768.1|4399_5533_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MILSKKVRLYPTEIQEQKLWQSVGTARFIYNWTLNRQQENYKNGGKFIKDGDLRKEITLMKKIEEYKWLSEVSNNVAKQAVKDCCNAYKNFFKGLKDKPCFKSRKKSKPSFYNDNVKLKVKTKLVNIEKVGWIKTKEQIPMNVKYTNPRVSFDGKYWYISVGIEQEQPKIELTNESIGIDVGIKDLAICSNGMTFKNINKSKEVKRLKKVLKRKQRKVSRKYEMNKIKKGGENRCQFKKTNNINKLRKEIKLLXRKLANIRSNHIHQATNKIVKTKPSRVVMETLNIKGMIKNKHLSKAVSEQCLYDFKVKMQYKCEFYGIKFVEADKWYPSSKTCSCCGSIKKDLKLSDRIYKCDCGLTIDRDFNASINLSRYKLA
>NC_015417.1|WP_039244075.1|18231_18456_-|alkaline-phosphatase
MILLKLKIKVSDLLGKYKKNQKWLCDVTGIRPATVQNYYYETIKRINVDDIESIYRAFYELDSTITIQDLLDFI
>NC_015417.1|WP_013720781.1|18614_18917_+|hypothetical-protein
MEIKTIYLIIQGKHKDKKGKLHNIVTYTDSLETIEKYKDKILGYEVASINDLNNSEVFDDTFGVDTLRVKEGIVTYKKYLVWYEGWDIEDYLEIGQWELI
>NC_015417.1|WP_019279139.1|19012_19765_+|hypothetical-protein
MEYYELIIQSYLKQNMHYKGVPEYLGSLINYCMLRDEKLEKLHNAKGLKGYVFNTLTPFEKDGMYKQNNIYQFSIRSINLDILKRIQNAIKNINNDEMAIVNTTLTTWHQKYMESLYTYTPSVLTLKEDEVPEKLKKIKSSSKYWVNGCSNKVLVDRIEKNMIKKYNFFTGNNIENISVVSDIQVLNEYPILIKYKKANVMANKFLIKIENSKLAQDIAFITLATGLLEKGSSIGCGFCQGNYYKEVMER
>NC_015417.1|WP_013720783.1|19761_21618_+|hypothetical-protein
MIKDINNVIGKTTEQLQSEIELNYKLKKCLYIKININNNTFDCYVNKDNENIDNIDLYNFFKVRESYSIQLDSNKTMLSSGDTRMKLTSVNMFSYITKIDTIKKMSTKCNLTIKECLVKIVKEYLKNLNDNFPVFYKEMLKPLKLKKDKLEEVLNNNFKKELQWIECDERKSLISDIKDFLLNNLDKIMKTVNDFIQKEKVTEVRIYLDYPLESYKKEFELYLKSKAFNKNKYNKLQDGILYGIHNNNFTLNEDKPYLQNLTKDNTTPHLVTLDESIHTYYLFEYLLHVLDWFNDLKYDVNSNLAIGYENDNGNALIVEYDNIPFPKSNIFINCTVTNITHVKTKDKDLKQYNDINRLNNSNREDKDNLEWQFNLRLLSGKMIGRYISNNNLKVSQGEFTANMKAILYRYRQPLWSYFKYGEKFSYRQMRKIVYRLMRELFELEDTKKNPLYFRIMDGMNFGISFIDFYENNKDGGIVMKLKELSETMKRKINDKDNINEIESDEEYYYCIGKLIKFLLSKSKTENKTYTLARPFFKVKSNKIIKEKIKMLMEKYCNEISFGSYRVENVFKMVNSYEINDKISEDAQTILMVSIMDNMNEIYVKDDNKKSQNDVKGEE
>NC_015417.1|WP_039244087.1|21620_22553_+|hypothetical-protein
MKKDNRVIGLVGVGVKNGSFNQGWDGYPRQKSDGEYVATDVCLKWAYRYFWNMQGKPVFSFAKMFKNKKNDIQHFSINEKYEDMFGAKAKSEDSIKFVNNLLGVVDVMNFGIAYAGDKSVSLTGVVQFGLGINKYEDTEVETFQILSPFRNSNEKSQDKLQKTSGTYTFVDEAHYMYSFTVNPAQMNEWKTIDENIEYTQEAYEDFKEGSLVAVSSLNTRTKINCQNEFAMFIELKKDSLLYLPNLDQYVTFRKEDDKNIIDITKLSEILNSDNVKDQIDSIEIYYNSFNLTLEGDINNAKKFNIITRGI
>NC_015417.1|WP_013720785.1|22590_22749_-|ribbon-helix-helix-domain-containing-protein
MGNKQLKTRTPIGSAIDTKLYNKLKAYSKETGIPISKLLDKSISLFLESTKK
>NC_015417.1|WP_013720786.1|22846_23980_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MILSKKVRLYPTEIQEQKLWQSVGTARFIYNWTLNRQQENYKNGGKFIKDGDLRKEITLMKKIEEYKWLSEVSNNVAKQAVKDCCNAYKNFFKGLKDKPCFKSRKKSKPSFYNDNVKLKVKTKLVNIEKVGWIKTKEQIPMNVKYTNPRVSFDGKYWYISVGIEQEQPKIELTNESIGIDVGIKDLAICSNGMTFKNINKSKEVKRLKKVLKRKQRKVSRKYEMNKIKKGGENRCQFKKTNNIIKLEKEIKLLHRKLANIRSNHIHQATNKIVKTKPSRVVMETLNIKGMIKNKHLSKAVSEQCLYDFKVKMQYKCEFYGIKFVEADKWYPSSKTCSCCGSIKKDLKLSDRIYKCDCGLTIDRDFNASINLSRYKLA
>NC_015417.1|WP_013720787.1|24146_24860_+|type-I-B-CRISPR-associated-protein-Cas5
MKGFKFNVSGKTAFFRKSDINQHINFSYSNIHKPCILGLLGAIIGLDKDKYYHALKHLRIAIVPNKSYFNKSIQVYNNTTKFGNKSLNNPTTLNIREQWLEDVSWYIYVITEDDDITYDKIYEYIKEFKSVYNIYLGRKEHIANVRFIEDIDIEDIHDDIAQINSLFPYSIIKDIEANKPEYCEDRISYFLKETMPIGYDDKGLYDYDTLVHTNHEIYELNNTNNIYKINNNILYFL
>NC_015417.1|WP_013720788.1|25788_27021_-|IS256-like-element-ISCbo4-family-transposase
MRNFEVPDFDYKEEVKKCKSLDDVMGKNGLIQRMLKDVIQNILEAEMEDHLGRDKYERNSENNSKNYRNGYSKKNIRSSFGDIDVDIPRDRNAEFEPKVIKKYETVCNELDKKVIGLYARGMSTRDIQAEIEDLYGITISPSMVSKITDKVIGAATAWQNRTLDRIYPIVYMDAMHFKVRDDNRIVSKAAYICMAYDMSGHKDILGIWVGESEGAKFWLSVCNDLKNRGVKQILIACMDGLRGLPDAIKTVYPEVSIQTCIVHQIRNSLKYIASKDKKEFIKDLKLIYKATTEELALLELDNLKEKWGSKYGIVIDSWYNNWDNLSTFFEFSPEIRKMIYTTNALEGFNRQIRKFTKTRTVFPTDESLKKSLYLATMEIMEKWTSPRQNWALTLGQLTITFGNKIDEFLA
>NC_015417.1|WP_013720789.1|27958_30445_+|CRISPR-associated-helicase/endonuclease-Cas3
MFDLKIDNIYAHINKEAKETLYQHSMLTQYYYNKIDKTHNYTEILTKMINEILIKEDKQSKETSKFISDLIIRMLYYHDIGKIGLGFQQNRMDNKLDEKYIDYTYHSELSALLFIDIEYNNIKEYTFSNNRKQNNQTKTLIKDVLLRLSFLIKCHHTGLYNFDKIGYIEDLKILQDKINNNPKIIKYYDKDNINIDFSGFGSYEYKEDNLIQYVFYKFLYSILITCDSFATHHFFINNEVELSLFDEKLIKECNNKYQSTDIYKNISNYKKDNNYFEDTNINKTRCDIFLETEENLTHNLDKNIYFLEACTGSGKTNISQNLALQLLINNKTLNKIIYTFPFNTLIEQTKGVLYNNFSEANVDIVAINSIEEIKNNDEDYDNDLLKYQFLQYPITLTSHINLFSILFGYGRRGNLAFSQICNSVIILDEIQSYNHLLWNKMIEIFNILSEFLNVKFVIMSATLPTLDLFLEECKRDSVCKLINDTKRYYDNPIFKERVSIDFSMLENESITIDDVENKIDDIIKDDTKGNRILVEFITVNSADEMYDRIKSKYNDDFLVFELTNQDNQLYRKYVINKLNEKDDKGDFKNKNVVVISTQVIEAGVDIDMEVGLKDISILESEEQFLGRINRNGKDKGYAYFFSMDKTKNTYRGDFRVSYDLKNEDIQQCLTNKDFTQYYLKCINHLKDESQKQGNNNLNEFNDNLVNIKFKAISESMKLIENKSVQLYLIYKYKTKDGKIINSADILEEYKELKSIPSYAERMIKESKLKKDMNLFTYNFNIYDDKYPQIYSDIINNSLYIVENGQEYMEDTEEQYIVFKSKFNLKKYS

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Crispr_ID: NC_015417_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015417_2

25061-25619

TypeV,TypeI-B

Consensus_repeat	Method
ATTAATAGATAACAAGATTTGTTTTTAAAT	PILER-CR
ATTAATAGATAACAAGATTTGTTTTTAAAT	CRISPRCasFinder
ATTAATAGATAACAAGATTTGTTTTTAAAT	CRT

8 spacers

cas5,cas14j,cas7b,cas8b1,cas3,cas14k

The CRISPR arrays of NC_015417_2

>merge|NC_015417|2|25061-25619|PILER-CR,CRISPRCasFinder,CRT
ATTAATAGATAACAAGATTTGTTTTTAAATTGTGTTATTCAAAGCACACCCAAATAGCGAATTATATTAATAGATAACAAGATTTGTTTTTAAATTTTAAATTGTTAAAATATTTTTTAAGTTCATTTTATGAATTAATAGATAACAAGATTTGTTTTTAAATTTAAGTATATTCCATTTTGATGAAAAACAAGCAATACATTAATAGATAACAAGATTTGTTTTTAAATCAAGAAGAAATAACTTTTGAAGATAAAGAAGATTTAATTAATAGATAACAAGATTTGTTTTTAAATCAATGAAGAAATGAAAGCATCCACCAATGAGTATACATTAATAGATAACAAGATTTGTTTTTAAATTTGAGTGAAAGATGGAATGTGTTTAAAATAAATGAGATTAATAGATAACAAGATTTGTTTTTAAATGCAAGGGATTATTATAAGAAAAATAAATGTGATATTATTAATAGATAACAAGATTTGTTTTTAAATGATATTGAAAGTGGAAGAGTAATTAAAGTTTGGACATTAATAGATAACAAGATTTGTGAGAATAT

>NC_015417|2|2|25061-25554|PILER-CR
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGTGTTATTCAAAGCACACCCAAATAGCGAATTAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTTAAATTGTTAAAATATTTTTTAAGTTCATTTTATGA
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTAAGTATATTCCATTTTGATGAAAAACAAGCAATAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	CAAGAAGAAATAACTTTTGAAGATAAAGAAGATTTA
ATTAATAGATAACAAGATTTGTTTTTAAAT	CAATGAAGAAATGAAAGCATCCACCAATGAGTATAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTGAGTGAAAGATGGAATGTGTTTAAAATAAATGAG
ATTAATAGATAACAAGATTTGTTTTTAAAT	GCAAGGGATTATTATAAGAAAAATAAATGTGATATT
ATTAATAGATAACAAGATTTGTTTTTAAAT

>NC_015417|2|2|25061-25619|CRISPRCasFinder
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGTGTTATTCAAAGCACACCCAAATAGCGAATTAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTTAAATTGTTAAAATATTTTTTAAGTTCATTTTATGA
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTAAGTATATTCCATTTTGATGAAAAACAAGCAATAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	CAAGAAGAAATAACTTTTGAAGATAAAGAAGATTTA
ATTAATAGATAACAAGATTTGTTTTTAAAT	CAATGAAGAAATGAAAGCATCCACCAATGAGTATAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTGAGTGAAAGATGGAATGTGTTTAAAATAAATGAG
ATTAATAGATAACAAGATTTGTTTTTAAAT	GCAAGGGATTATTATAAGAAAAATAAATGTGATATT
ATTAATAGATAACAAGATTTGTTTTTAAAT	GATATTGAAAGTGGAAGAGTAATTAAAGTTTGGAC
ATTAATAGATAACAAGATTTGTGAGAATAT

>NC_015417|2|2|25061-25619|CRT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGTGTTATTCAAAGCACACCCAAATAGCGAATTAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTTAAATTGTTAAAATATTTTTTAAGTTCATTTTATGA
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTAAGTATATTCCATTTTGATGAAAAACAAGCAATAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	CAAGAAGAAATAACTTTTGAAGATAAAGAAGATTTA
ATTAATAGATAACAAGATTTGTTTTTAAAT	CAATGAAGAAATGAAAGCATCCACCAATGAGTATAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TTGAGTGAAAGATGGAATGTGTTTAAAATAAATGAG
ATTAATAGATAACAAGATTTGTTTTTAAAT	GCAAGGGATTATTATAAGAAAAATAAATGTGATATT
ATTAATAGATAACAAGATTTGTTTTTAAAT	GATATTGAAAGTGGAAGAGTAATTAAAGTTTGGAC
ATTAATAGATAACAAGATTTGTGAGAATAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015417.1\|WP_013720779.1\|15734_16076_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720788.1\|25788_27021_-\|IS256-like-element-ISCbo4-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_015417.1\|WP_013720785.1\|22590_22749_-\|ribbon-helix-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|289422
NC_015417.1\|WP_039244034.1\|30547_31141_+\|IS607-like-element-ISCbo10-family-transposase	unknown	unknown	gnl\|CDD\|225296
NC_015417.1\|WP_013720778.1\|14969_15656_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_015417.1\|WP_013720793.1\|34256_35663_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319271
NC_015417.1\|WP_019279139.1\|19012_19765_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720786.1\|22846_23980_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NC_015417.1\|WP_013720791.1\|31177_32590_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	gnl\|CDD\|223747
NC_015417.1\|WP_013720795.1\|36831_37215_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720796.1\|37272_39222_+\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NC_015417.1\|WP_013720787.1\|24146_24860_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_015417.1\|WP_013720792.1\|33135_33807_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NC_015417.1\|WP_013720789.1\|27958_30445_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224124
NC_015417.1\|WP_039244075.1\|18231_18456_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|379188
NC_015417.1\|WP_013720781.1\|18614_18917_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720783.1\|19761_21618_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NC_015417.1\|WP_039244087.1\|21620_22553_+\|hypothetical-protein	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015417.1\|WP_013720794.1\|35655_36750_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NC_015417.1\|WP_019279003.1\|39319_39601_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015417.1\|WP_013720788.1\|25788_27021_-\|IS256-like-element-ISCbo4-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.66787e-122
NC_015417.1\|WP_013720785.1\|22590_22749_-\|ribbon-helix-helix-domain-containing-protein	gnl\|CDD\|289422	pfam12651, RHH_3, Ribbon-helix-helix domain. This short bacterial protein contains a ribbon-helix-helix domain that is likely to be DNA-binding.	1.83724e-10
NC_015417.1\|WP_039244034.1\|30547_31141_+\|IS607-like-element-ISCbo10-family-transposase	gnl\|CDD\|225296	COG2452, COG2452, Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair].	1.97761e-55
NC_015417.1\|WP_013720778.1\|14969_15656_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.69546e-13
NC_015417.1\|WP_013720793.1\|34256_35663_+\|hypothetical-protein	gnl\|CDD\|319271	cd16414, dndB_like, DNA-sulfur modification-associated domain. Family of proteins related to dndB. dndB acts in the regulation of DNA modifications, including DNA phosphorothioation. Both have a conserved DGQHR sequence motif. These proteins show similarity to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, and other members of the ParB/Srx superfamily.	0.00148939
NC_015417.1\|WP_013720794.1\|35655_36750_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	0.000105406
NC_015417.1\|WP_013720786.1\|22846_23980_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.25547e-33
NC_015417.1\|WP_013720791.1\|31177_32590_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.45332e-20
NC_015417.1\|WP_013720796.1\|37272_39222_+\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_015417.1\|WP_013720792.1\|33135_33807_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.76702e-20
NC_015417.1\|WP_039244075.1\|18231_18456_-\|alkaline-phosphatase	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	0.000243887
NC_015417.1\|WP_013720787.1\|24146_24860_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.64825e-28
NC_015417.1\|WP_013720789.1\|27958_30445_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.75234e-30
NC_015417.1\|WP_039244087.1\|21620_22553_+\|hypothetical-protein	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.90234e-17

>NC_015417.1|WP_013720787.1|24146_24860_+|type-I-B-CRISPR-associated-protein-Cas5
MKGFKFNVSGKTAFFRKSDINQHINFSYSNIHKPCILGLLGAIIGLDKDKYYHALKHLRIAIVPNKSYFNKSIQVYNNTTKFGNKSLNNPTTLNIREQWLEDVSWYIYVITEDDDITYDKIYEYIKEFKSVYNIYLGRKEHIANVRFIEDIDIEDIHDDIAQINSLFPYSIIKDIEANKPEYCEDRISYFLKETMPIGYDDKGLYDYDTLVHTNHEIYELNNTNNIYKINNNILYFL
>NC_015417.1|WP_013720786.1|22846_23980_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MILSKKVRLYPTEIQEQKLWQSVGTARFIYNWTLNRQQENYKNGGKFIKDGDLRKEITLMKKIEEYKWLSEVSNNVAKQAVKDCCNAYKNFFKGLKDKPCFKSRKKSKPSFYNDNVKLKVKTKLVNIEKVGWIKTKEQIPMNVKYTNPRVSFDGKYWYISVGIEQEQPKIELTNESIGIDVGIKDLAICSNGMTFKNINKSKEVKRLKKVLKRKQRKVSRKYEMNKIKKGGENRCQFKKTNNIIKLEKEIKLLHRKLANIRSNHIHQATNKIVKTKPSRVVMETLNIKGMIKNKHLSKAVSEQCLYDFKVKMQYKCEFYGIKFVEADKWYPSSKTCSCCGSIKKDLKLSDRIYKCDCGLTIDRDFNASINLSRYKLA
>NC_015417.1|WP_013720785.1|22590_22749_-|ribbon-helix-helix-domain-containing-protein
MGNKQLKTRTPIGSAIDTKLYNKLKAYSKETGIPISKLLDKSISLFLESTKK
>NC_015417.1|WP_039244087.1|21620_22553_+|hypothetical-protein
MKKDNRVIGLVGVGVKNGSFNQGWDGYPRQKSDGEYVATDVCLKWAYRYFWNMQGKPVFSFAKMFKNKKNDIQHFSINEKYEDMFGAKAKSEDSIKFVNNLLGVVDVMNFGIAYAGDKSVSLTGVVQFGLGINKYEDTEVETFQILSPFRNSNEKSQDKLQKTSGTYTFVDEAHYMYSFTVNPAQMNEWKTIDENIEYTQEAYEDFKEGSLVAVSSLNTRTKINCQNEFAMFIELKKDSLLYLPNLDQYVTFRKEDDKNIIDITKLSEILNSDNVKDQIDSIEIYYNSFNLTLEGDINNAKKFNIITRGI
>NC_015417.1|WP_013720783.1|19761_21618_+|hypothetical-protein
MIKDINNVIGKTTEQLQSEIELNYKLKKCLYIKININNNTFDCYVNKDNENIDNIDLYNFFKVRESYSIQLDSNKTMLSSGDTRMKLTSVNMFSYITKIDTIKKMSTKCNLTIKECLVKIVKEYLKNLNDNFPVFYKEMLKPLKLKKDKLEEVLNNNFKKELQWIECDERKSLISDIKDFLLNNLDKIMKTVNDFIQKEKVTEVRIYLDYPLESYKKEFELYLKSKAFNKNKYNKLQDGILYGIHNNNFTLNEDKPYLQNLTKDNTTPHLVTLDESIHTYYLFEYLLHVLDWFNDLKYDVNSNLAIGYENDNGNALIVEYDNIPFPKSNIFINCTVTNITHVKTKDKDLKQYNDINRLNNSNREDKDNLEWQFNLRLLSGKMIGRYISNNNLKVSQGEFTANMKAILYRYRQPLWSYFKYGEKFSYRQMRKIVYRLMRELFELEDTKKNPLYFRIMDGMNFGISFIDFYENNKDGGIVMKLKELSETMKRKINDKDNINEIESDEEYYYCIGKLIKFLLSKSKTENKTYTLARPFFKVKSNKIIKEKIKMLMEKYCNEISFGSYRVENVFKMVNSYEINDKISEDAQTILMVSIMDNMNEIYVKDDNKKSQNDVKGEE
>NC_015417.1|WP_019279139.1|19012_19765_+|hypothetical-protein
MEYYELIIQSYLKQNMHYKGVPEYLGSLINYCMLRDEKLEKLHNAKGLKGYVFNTLTPFEKDGMYKQNNIYQFSIRSINLDILKRIQNAIKNINNDEMAIVNTTLTTWHQKYMESLYTYTPSVLTLKEDEVPEKLKKIKSSSKYWVNGCSNKVLVDRIEKNMIKKYNFFTGNNIENISVVSDIQVLNEYPILIKYKKANVMANKFLIKIENSKLAQDIAFITLATGLLEKGSSIGCGFCQGNYYKEVMER
>NC_015417.1|WP_013720781.1|18614_18917_+|hypothetical-protein
MEIKTIYLIIQGKHKDKKGKLHNIVTYTDSLETIEKYKDKILGYEVASINDLNNSEVFDDTFGVDTLRVKEGIVTYKKYLVWYEGWDIEDYLEIGQWELI
>NC_015417.1|WP_039244075.1|18231_18456_-|alkaline-phosphatase
MILLKLKIKVSDLLGKYKKNQKWLCDVTGIRPATVQNYYYETIKRINVDDIESIYRAFYELDSTITIQDLLDFI
>NC_015417.1|WP_013720779.1|15734_16076_+|hypothetical-protein
MEEIIMALGYLLLLFIVMSAISSVGIVLLYVIKNETIKNILFYCLAMWSMGIACLAAISLPTNFLGHRLINCLLGFISIMAIILKIKDPQKPNIAYIIVTASTLLGMYSLFFS
>NC_015417.1|WP_013720778.1|14969_15656_+|HAMP-domain-containing-histidine-kinase
MNNTYRIYIFITFYKFYATDKLKREKENLIKSLSHDIRTPLTAIISYSDFIKNKRYNSNEKLESYIEIIQNKAYQIQELTNLLLNTDIKPPNSDNTPLLEGKLMFEQFISEFVSALEDENFEVEIDRLALVDFKAKFDVQDISRIFDNIYSNIIKYASNLGKIQLEIFIEDNNLVFTQTNVIKDKIPNNIESHGIGLNNINKIVKSYNGEMKYILTQKIYKIEIKIPL
>NC_015417.1|WP_013720788.1|25788_27021_-|IS256-like-element-ISCbo4-family-transposase
MRNFEVPDFDYKEEVKKCKSLDDVMGKNGLIQRMLKDVIQNILEAEMEDHLGRDKYERNSENNSKNYRNGYSKKNIRSSFGDIDVDIPRDRNAEFEPKVIKKYETVCNELDKKVIGLYARGMSTRDIQAEIEDLYGITISPSMVSKITDKVIGAATAWQNRTLDRIYPIVYMDAMHFKVRDDNRIVSKAAYICMAYDMSGHKDILGIWVGESEGAKFWLSVCNDLKNRGVKQILIACMDGLRGLPDAIKTVYPEVSIQTCIVHQIRNSLKYIASKDKKEFIKDLKLIYKATTEELALLELDNLKEKWGSKYGIVIDSWYNNWDNLSTFFEFSPEIRKMIYTTNALEGFNRQIRKFTKTRTVFPTDESLKKSLYLATMEIMEKWTSPRQNWALTLGQLTITFGNKIDEFLA
>NC_015417.1|WP_013720789.1|27958_30445_+|CRISPR-associated-helicase/endonuclease-Cas3
MFDLKIDNIYAHINKEAKETLYQHSMLTQYYYNKIDKTHNYTEILTKMINEILIKEDKQSKETSKFISDLIIRMLYYHDIGKIGLGFQQNRMDNKLDEKYIDYTYHSELSALLFIDIEYNNIKEYTFSNNRKQNNQTKTLIKDVLLRLSFLIKCHHTGLYNFDKIGYIEDLKILQDKINNNPKIIKYYDKDNINIDFSGFGSYEYKEDNLIQYVFYKFLYSILITCDSFATHHFFINNEVELSLFDEKLIKECNNKYQSTDIYKNISNYKKDNNYFEDTNINKTRCDIFLETEENLTHNLDKNIYFLEACTGSGKTNISQNLALQLLINNKTLNKIIYTFPFNTLIEQTKGVLYNNFSEANVDIVAINSIEEIKNNDEDYDNDLLKYQFLQYPITLTSHINLFSILFGYGRRGNLAFSQICNSVIILDEIQSYNHLLWNKMIEIFNILSEFLNVKFVIMSATLPTLDLFLEECKRDSVCKLINDTKRYYDNPIFKERVSIDFSMLENESITIDDVENKIDDIIKDDTKGNRILVEFITVNSADEMYDRIKSKYNDDFLVFELTNQDNQLYRKYVINKLNEKDDKGDFKNKNVVVISTQVIEAGVDIDMEVGLKDISILESEEQFLGRINRNGKDKGYAYFFSMDKTKNTYRGDFRVSYDLKNEDIQQCLTNKDFTQYYLKCINHLKDESQKQGNNNLNEFNDNLVNIKFKAISESMKLIENKSVQLYLIYKYKTKDGKIINSADILEEYKELKSIPSYAERMIKESKLKKDMNLFTYNFNIYDDKYPQIYSDIINNSLYIVENGQEYMEDTEEQYIVFKSKFNLKKYS
>NC_015417.1|WP_039244034.1|30547_31141_+|IS607-like-element-ISCbo10-family-transposase
MKSKEVLELLQITRPTLTKYVKEGIIKTITLPNGRYDYNQEDVFKLFNKGVERKTYIYARVSTPKQKKDLENQVQLLKQFCFSNGWMINNVFQDVASGISFDKRKDFFKMLDDIIQNKVERVVITYKDRLSRVGFELFYYLFKKYHCEIVVMSEIGSEKLDSQEVFEEIVSLLHCYSMKMYSKRKCNKIKEVLQEED
>NC_015417.1|WP_013720791.1|31177_32590_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MTTKKDDNTVQRVEKHMINQNHELYELLNHYTFLSKNLYNYANYQLRQVFILTSKLKEDEELTTEQHEYLNSINAKVNEFNELRKVNFEKAKQRAIKQGKELNKKLKLINYFNEDNKYLGYDFLEFLLKDGIDYKSLMSQVSQQTLKLLDKNWISFFESIKDWSKHKEKYNGRPKLPKYKKKNGKNILVFTNQNCKQKKGYIQFPKCFNKYELKTNINGNLQQVRILPRNKHYVIEVVYKIEKKEKLNDNGKYISIDIGLDNFATVVNNIGLKPIIINGKGLKSINKYYNKKLSYYKEIAKRMNNLDYTNRMNRLTIKRNNKIIDFVHKASKKVIDYALANNINTIIVGNNKDWKRESNMSKVVNQSFVGIPHQEFINKLIYKCENVGLNIIITEESYTSGTSFLDNELPNKENYNKKRRVYRGLFVSNNGVKINADVNGAYQIMRKVLSNVKADEIEGVGLHPIRVNIA
>NC_015417.1|WP_013720792.1|33135_33807_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MLRSIEALKEIQRRMEVRRGDVWMVEIPQEAKEVFGSNIQTGLRPCIIISGEGNNKHANIVNILPISSKINKVYPQHTEITTYEDLRDCGLTKRSIVLSEQMMTIDKSKLIDKLGRANDKLMQRVEKGLEVQQGKNLRCVKRDNVRNFNKERFSFKKAFDKIEMINKAKDLDAELYMYLYGELKEYCEDHNVKYYEVINKYNNIKDRFKFNPTIMNNMVAMGY
>NC_015417.1|WP_013720793.1|34256_35663_+|hypothetical-protein
MKIKSRDELGKNKNEIDKLLEQELPKMYALYPKMVYDVAEQLEDKNITIGTISGLFGGITPTYKLEEVDELGSFLKAIYEVGTKYSKNKILIIPNLEKLNPENFYTETEINSINLYKKEVSKENNIIKLYVRKNAENHYVCPYISMVEYVDYYKRGLIIYNPNTQRETTKKMVKGQINEFITIHQENVNKIYNDLKNDRFNPNMLTLNIRDNEGDDPQFDDGGMNVGDFGWLKIKVDGRQHSYVDLLDGQHRTSAQEIYVEEYPNTDKYNMLNVFVFNEEQAIHHIIQENSGTKIDENSLQRRDPDNKGVAMAKELKTLSKELKGKVANDLIELTKHCQYTDVLTLGSAINNYFDIDGRKEYREIRSYLSKFFDVAIDCYKDYFNKRNLQPKELFYRKNTFIAFCDIAKKLYKFKDWEDKAFDIFEKLSIEEIESVSGNKKILKPNDYKIISNKLQKSLAEREVAIDG
>NC_015417.1|WP_013720794.1|35655_36750_+|site-specific-integrase
MANVKQYKRRFVVTEEMYNEDVKNRFIDYYYDNEQTKLNIKRTFYLTNFYMEKDLDKDIYNFNKYEIESLLKSFKATSEGSLAVRLTHIKKYIDFCISMGIRSNAINFCDTIANLKDYVVRNLDKYKYITREQLYNICDIMESSQIAVIFILFFEGIVGKEKCEMRNLKVEDVDFDNNSITIRAYDEINPRTGEIIHKPERILTNVHPRTMEYIKDAIEETVMIMPESKLFTDPEKDVAIKTGKIGKNPAPHYVVQNDYVVRKSSRKLKSDEEEENTPISMSTIINRIYYATDYFVDDENLYFVKKLNTTTLEQSGMIEELEKIEAQKGKLVVQDFKDVIASRNKRTYHSLKRLWDAIKKEKSE
>NC_015417.1|WP_013720795.1|36831_37215_+|hypothetical-protein
MGKILSKELIINGVKEREIEFEKMKNKLDDTSTILSDYRNIVLRKRKLENELQLREFEENFNNKDMDKLKSNFEILDLIHKTNLTVNKILHIMQSNNWTIKDIYKEYEKGYTRNILALLSKSNKNIC
>NC_015417.1|WP_013720796.1|37272_39222_+|NAD-dependent-DNA-ligase-LigA
MEDKTQRVKELIKELNQASDKYYNSDETVMTDKEWDDKFDKLKQLEQDTGIILSNSPTQKVGYEVKSKLDKVVHNIPLKSLGKTKSIGDLNKFIGSNEVIIMDKGDGLTCELIYENGQLLQGSTRGNGEIGEDITHNVKTFKNIPLQIDFKGYLKLSGESVILDEDFELINSKLDDEDKYSNSRNLVAGSVRQLDSNICDKRNVKFYAFSLLECEGVDFITKEEQLEFLSRLGFETIEYIKYNNSEDLEQVISKMQKSAYEKGFPIDGLVFAYNNIEYANLLGDTLHHPLHSIAYKFYDEEYETQYITTEWQVSRTGMINPVARFKPVEIEGSVVERATLHNLDYFEDLKLGQGDTIKVIKANQVIPKVMSNDTMSNTEIIPTECPVCGGKTEEKLLKTARVLICNNPECSAKHISRITHYCSRNAMNIDGLSEKTIEKFVNLGYLKDIDDIYKLEQYKEEIINIDGLGTKSYNNMIEAIEKSKYCKLENFIFALGVPNVGLGTAKLLVKQFKSIDKIMNCNLTEIYGIEGIGDVVGSEIYNYFIINTDSINLVNKLLKFIDFEEVKESSSNKLEGKTFVITGDVHVFKNRNEVKAKIEEMGGKVTGSVSKKTDYLINNDVESTSSKNQKAKDLNIPIITEEEFVEMIK
>NC_015417.1|WP_019279003.1|39319_39601_+|hypothetical-protein
MLNNIIKVEDYEVEVGDVDWELTSRYILSRELIITVKKNNEVVLSSKGKLKSEFFNYLGFLINDKGVLKTIEQIYDNPNNFLLENYELENGFF

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Crispr_ID: NC_015417_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015417_3

27115-27925

TypeV

Consensus_repeat	Method
ATTAATAGATAACAAGATTTGTTTTTAAAT	CRISPRCasFinder
ATTAATAGATAACAAGATTTGTTTTTAAAT	CRT
ATTAATAGATAACAAGATTTGTTTTTAAAT	PILER-CR

12 spacers

cas5,cas14j,cas7b,cas8b1,cas3,cas14k

The CRISPR arrays of NC_015417_3

>merge|NC_015417|3|27115-27925|CRISPRCasFinder,CRT,PILER-CR
CAACCTACATCCCCAGATTTGTTTTTAAATATTAGTTTACCACACTTTGGACACATTCTCATTAGATTAATAGATAACAAGATTTGTTTTTAAATCCGATAGTGTATTCTTTACCTTCAAATTCTACTTTAATTAATAGATAACAAGATTTGTTTTTAAATATATAATCTTTTTTATGGAGGTGATACACTTGATATTAATAGATAACAAGATTTGTTTTTAAATTGTTTAGCTAGGTAGTTTTGATAAACTTTAGTATTCATTAATAGATAACAAGATTTGTTTTTAAATTGAAATTGAGAATAAGCAAAAATCAATTCTTGTAACATTAATAGATAACAAGATTTGTTTTTAAATTCTGTACTCTCTTCTATAGTCATTTTTAATAGTGTATTAATAGATAACAAGATTTGTTTTTAAATCATTTATATGGTTCTTGCTTGTCCGATTGACTTTATAATTAATAGATAACAAGATTTGTTTTTAAATTCGTAATTGTTAATTATTATTTCAATTTTCTTATATTAATAGATAACAAGATTTGTTTTTAAATTATAAGTATAGTGATTTTAAAAATATTGATGATCTAGATTAATAGATAACAAGATTTGTTTTTAAATAAAGTAGTTATTTTGAAACTTATAAATACATTAATCATTAATAAATAACAATATTTGTTTAAACTTTAATTTGCATATGTTAAAATAGAAATAAATGTAGATTAATCTATAATATAGTTTATTTTTAAATATATTTAGTTTTAATTCGCAAGGATTAGTATATTAATAGATAACATTATATGTTCTTAAAC

>NC_015417|3|3|27115-27925|CRISPRCasFinder
CAACCTACATCCCCAGATTTGTTTTTAAAT	ATTAGTTTACCACACTTTGGACACATTCTCATTAG
ATTAATAGATAACAAGATTTGTTTTTAAAT	CCGATAGTGTATTCTTTACCTTCAAATTCTACTTTA
ATTAATAGATAACAAGATTTGTTTTTAAAT	ATATAATCTTTTTTATGGAGGTGATACACTTGAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGTTTAGCTAGGTAGTTTTGATAAACTTTAGTATTC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGAAATTGAGAATAAGCAAAAATCAATTCTTGTAAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TCTGTACTCTCTTCTATAGTCATTTTTAATAGTGT
ATTAATAGATAACAAGATTTGTTTTTAAAT	CATTTATATGGTTCTTGCTTGTCCGATTGACTTTATA
ATTAATAGATAACAAGATTTGTTTTTAAAT	TCGTAATTGTTAATTATTATTTCAATTTTCTTAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TATAAGTATAGTGATTTTAAAAATATTGATGATCTAG
ATTAATAGATAACAAGATTTGTTTTTAAAT	AAAGTAGTTATTTTGAAACTTATAAATACATTAATC
ATTAATAAATAACAATATTTGTTTAAACTT	TAATTTGCATATGTTAAAATAGAAATAAATGTAG
ATTAATCTATAATATAGTTTATTTTTAAAT	ATATTTAGTTTTAATTCGCAAGGATTAGTAT
ATTAATAGATAACATTATATGTTCTTAAAC

>NC_015417|3|3|27115-27800|CRT
CAACCTACATCCCCAGATTTGTTTTTAAAT	ATTAGTTTACCACACTTTGGACACATTCTCATTAG
ATTAATAGATAACAAGATTTGTTTTTAAAT	CCGATAGTGTATTCTTTACCTTCAAATTCTACTTTA
ATTAATAGATAACAAGATTTGTTTTTAAAT	ATATAATCTTTTTTATGGAGGTGATACACTTGAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGTTTAGCTAGGTAGTTTTGATAAACTTTAGTATTC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGAAATTGAGAATAAGCAAAAATCAATTCTTGTAAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TCTGTACTCTCTTCTATAGTCATTTTTAATAGTGT
ATTAATAGATAACAAGATTTGTTTTTAAAT	CATTTATATGGTTCTTGCTTGTCCGATTGACTTTATA
ATTAATAGATAACAAGATTTGTTTTTAAAT	TCGTAATTGTTAATTATTATTTCAATTTTCTTAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TATAAGTATAGTGATTTTAAAAATATTGATGATCTAG
ATTAATAGATAACAAGATTTGTTTTTAAAT	AAAGTAGTTATTTTGAAACTTATAAATACATTAATC
ATTAATAAATAACAATATTTGTTTAAACTT

>NC_015417|3|3|27180-27667|PILER-CR
ATTAATAGATAACAAGATTTGTTTTTAAAT	CCGATAGTGTATTCTTTACCTTCAAATTCTACTTTA
ATTAATAGATAACAAGATTTGTTTTTAAAT	ATATAATCTTTTTTATGGAGGTGATACACTTGAT
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGTTTAGCTAGGTAGTTTTGATAAACTTTAGTATTC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TGAAATTGAGAATAAGCAAAAATCAATTCTTGTAAC
ATTAATAGATAACAAGATTTGTTTTTAAAT	TCTGTACTCTCTTCTATAGTCATTTTTAATAGTGT
ATTAATAGATAACAAGATTTGTTTTTAAAT	CATTTATATGGTTCTTGCTTGTCCGATTGACTTTATA
ATTAATAGATAACAAGATTTGTTTTTAAAT	TCGTAATTGTTAATTATTATTTCAATTTTCTTAT
ATTAATAGATAACAAGATTTGTTTTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015417.1\|WP_013720779.1\|15734_16076_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720788.1\|25788_27021_-\|IS256-like-element-ISCbo4-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_015417.1\|WP_013720785.1\|22590_22749_-\|ribbon-helix-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|289422
NC_015417.1\|WP_039244034.1\|30547_31141_+\|IS607-like-element-ISCbo10-family-transposase	unknown	unknown	gnl\|CDD\|225296
NC_015417.1\|WP_013720793.1\|34256_35663_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319271
NC_015417.1\|WP_019279139.1\|19012_19765_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720786.1\|22846_23980_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14j	-	gnl\|CDD\|223747
NC_015417.1\|WP_019279003.1\|39319_39601_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720791.1\|31177_32590_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	gnl\|CDD\|223747
NC_015417.1\|WP_013720795.1\|36831_37215_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720796.1\|37272_39222_+\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NC_015417.1\|WP_013720787.1\|24146_24860_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_015417.1\|WP_013720792.1\|33135_33807_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NC_015417.1\|WP_013720798.1\|39632_40061_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720789.1\|27958_30445_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224124
NC_015417.1\|WP_013720781.1\|18614_18917_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720783.1\|19761_21618_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NC_015417.1\|WP_039244087.1\|21620_22553_+\|hypothetical-protein	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015417.1\|WP_013720794.1\|35655_36750_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NC_015417.1\|WP_039244075.1\|18231_18456_-\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|379188

Protein	Function_ID	Function_description	E-value
NC_015417.1\|WP_013720788.1\|25788_27021_-\|IS256-like-element-ISCbo4-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.66787e-122
NC_015417.1\|WP_013720785.1\|22590_22749_-\|ribbon-helix-helix-domain-containing-protein	gnl\|CDD\|289422	pfam12651, RHH_3, Ribbon-helix-helix domain. This short bacterial protein contains a ribbon-helix-helix domain that is likely to be DNA-binding.	1.83724e-10
NC_015417.1\|WP_039244034.1\|30547_31141_+\|IS607-like-element-ISCbo10-family-transposase	gnl\|CDD\|225296	COG2452, COG2452, Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair].	1.97761e-55
NC_015417.1\|WP_013720793.1\|34256_35663_+\|hypothetical-protein	gnl\|CDD\|319271	cd16414, dndB_like, DNA-sulfur modification-associated domain. Family of proteins related to dndB. dndB acts in the regulation of DNA modifications, including DNA phosphorothioation. Both have a conserved DGQHR sequence motif. These proteins show similarity to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, and other members of the ParB/Srx superfamily.	0.00148939
NC_015417.1\|WP_013720794.1\|35655_36750_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	0.000105406
NC_015417.1\|WP_013720786.1\|22846_23980_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.25547e-33
NC_015417.1\|WP_013720791.1\|31177_32590_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.45332e-20
NC_015417.1\|WP_013720796.1\|37272_39222_+\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_015417.1\|WP_013720792.1\|33135_33807_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.76702e-20
NC_015417.1\|WP_039244075.1\|18231_18456_-\|alkaline-phosphatase	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	0.000243887
NC_015417.1\|WP_013720787.1\|24146_24860_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.64825e-28
NC_015417.1\|WP_013720789.1\|27958_30445_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.75234e-30
NC_015417.1\|WP_039244087.1\|21620_22553_+\|hypothetical-protein	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.90234e-17

>NC_015417.1|WP_013720788.1|25788_27021_-|IS256-like-element-ISCbo4-family-transposase
MRNFEVPDFDYKEEVKKCKSLDDVMGKNGLIQRMLKDVIQNILEAEMEDHLGRDKYERNSENNSKNYRNGYSKKNIRSSFGDIDVDIPRDRNAEFEPKVIKKYETVCNELDKKVIGLYARGMSTRDIQAEIEDLYGITISPSMVSKITDKVIGAATAWQNRTLDRIYPIVYMDAMHFKVRDDNRIVSKAAYICMAYDMSGHKDILGIWVGESEGAKFWLSVCNDLKNRGVKQILIACMDGLRGLPDAIKTVYPEVSIQTCIVHQIRNSLKYIASKDKKEFIKDLKLIYKATTEELALLELDNLKEKWGSKYGIVIDSWYNNWDNLSTFFEFSPEIRKMIYTTNALEGFNRQIRKFTKTRTVFPTDESLKKSLYLATMEIMEKWTSPRQNWALTLGQLTITFGNKIDEFLA
>NC_015417.1|WP_013720787.1|24146_24860_+|type-I-B-CRISPR-associated-protein-Cas5
MKGFKFNVSGKTAFFRKSDINQHINFSYSNIHKPCILGLLGAIIGLDKDKYYHALKHLRIAIVPNKSYFNKSIQVYNNTTKFGNKSLNNPTTLNIREQWLEDVSWYIYVITEDDDITYDKIYEYIKEFKSVYNIYLGRKEHIANVRFIEDIDIEDIHDDIAQINSLFPYSIIKDIEANKPEYCEDRISYFLKETMPIGYDDKGLYDYDTLVHTNHEIYELNNTNNIYKINNNILYFL
>NC_015417.1|WP_013720786.1|22846_23980_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MILSKKVRLYPTEIQEQKLWQSVGTARFIYNWTLNRQQENYKNGGKFIKDGDLRKEITLMKKIEEYKWLSEVSNNVAKQAVKDCCNAYKNFFKGLKDKPCFKSRKKSKPSFYNDNVKLKVKTKLVNIEKVGWIKTKEQIPMNVKYTNPRVSFDGKYWYISVGIEQEQPKIELTNESIGIDVGIKDLAICSNGMTFKNINKSKEVKRLKKVLKRKQRKVSRKYEMNKIKKGGENRCQFKKTNNIIKLEKEIKLLHRKLANIRSNHIHQATNKIVKTKPSRVVMETLNIKGMIKNKHLSKAVSEQCLYDFKVKMQYKCEFYGIKFVEADKWYPSSKTCSCCGSIKKDLKLSDRIYKCDCGLTIDRDFNASINLSRYKLA
>NC_015417.1|WP_013720785.1|22590_22749_-|ribbon-helix-helix-domain-containing-protein
MGNKQLKTRTPIGSAIDTKLYNKLKAYSKETGIPISKLLDKSISLFLESTKK
>NC_015417.1|WP_039244087.1|21620_22553_+|hypothetical-protein
MKKDNRVIGLVGVGVKNGSFNQGWDGYPRQKSDGEYVATDVCLKWAYRYFWNMQGKPVFSFAKMFKNKKNDIQHFSINEKYEDMFGAKAKSEDSIKFVNNLLGVVDVMNFGIAYAGDKSVSLTGVVQFGLGINKYEDTEVETFQILSPFRNSNEKSQDKLQKTSGTYTFVDEAHYMYSFTVNPAQMNEWKTIDENIEYTQEAYEDFKEGSLVAVSSLNTRTKINCQNEFAMFIELKKDSLLYLPNLDQYVTFRKEDDKNIIDITKLSEILNSDNVKDQIDSIEIYYNSFNLTLEGDINNAKKFNIITRGI
>NC_015417.1|WP_013720783.1|19761_21618_+|hypothetical-protein
MIKDINNVIGKTTEQLQSEIELNYKLKKCLYIKININNNTFDCYVNKDNENIDNIDLYNFFKVRESYSIQLDSNKTMLSSGDTRMKLTSVNMFSYITKIDTIKKMSTKCNLTIKECLVKIVKEYLKNLNDNFPVFYKEMLKPLKLKKDKLEEVLNNNFKKELQWIECDERKSLISDIKDFLLNNLDKIMKTVNDFIQKEKVTEVRIYLDYPLESYKKEFELYLKSKAFNKNKYNKLQDGILYGIHNNNFTLNEDKPYLQNLTKDNTTPHLVTLDESIHTYYLFEYLLHVLDWFNDLKYDVNSNLAIGYENDNGNALIVEYDNIPFPKSNIFINCTVTNITHVKTKDKDLKQYNDINRLNNSNREDKDNLEWQFNLRLLSGKMIGRYISNNNLKVSQGEFTANMKAILYRYRQPLWSYFKYGEKFSYRQMRKIVYRLMRELFELEDTKKNPLYFRIMDGMNFGISFIDFYENNKDGGIVMKLKELSETMKRKINDKDNINEIESDEEYYYCIGKLIKFLLSKSKTENKTYTLARPFFKVKSNKIIKEKIKMLMEKYCNEISFGSYRVENVFKMVNSYEINDKISEDAQTILMVSIMDNMNEIYVKDDNKKSQNDVKGEE
>NC_015417.1|WP_019279139.1|19012_19765_+|hypothetical-protein
MEYYELIIQSYLKQNMHYKGVPEYLGSLINYCMLRDEKLEKLHNAKGLKGYVFNTLTPFEKDGMYKQNNIYQFSIRSINLDILKRIQNAIKNINNDEMAIVNTTLTTWHQKYMESLYTYTPSVLTLKEDEVPEKLKKIKSSSKYWVNGCSNKVLVDRIEKNMIKKYNFFTGNNIENISVVSDIQVLNEYPILIKYKKANVMANKFLIKIENSKLAQDIAFITLATGLLEKGSSIGCGFCQGNYYKEVMER
>NC_015417.1|WP_013720781.1|18614_18917_+|hypothetical-protein
MEIKTIYLIIQGKHKDKKGKLHNIVTYTDSLETIEKYKDKILGYEVASINDLNNSEVFDDTFGVDTLRVKEGIVTYKKYLVWYEGWDIEDYLEIGQWELI
>NC_015417.1|WP_039244075.1|18231_18456_-|alkaline-phosphatase
MILLKLKIKVSDLLGKYKKNQKWLCDVTGIRPATVQNYYYETIKRINVDDIESIYRAFYELDSTITIQDLLDFI
>NC_015417.1|WP_013720779.1|15734_16076_+|hypothetical-protein
MEEIIMALGYLLLLFIVMSAISSVGIVLLYVIKNETIKNILFYCLAMWSMGIACLAAISLPTNFLGHRLINCLLGFISIMAIILKIKDPQKPNIAYIIVTASTLLGMYSLFFS
>NC_015417.1|WP_013720789.1|27958_30445_+|CRISPR-associated-helicase/endonuclease-Cas3
MFDLKIDNIYAHINKEAKETLYQHSMLTQYYYNKIDKTHNYTEILTKMINEILIKEDKQSKETSKFISDLIIRMLYYHDIGKIGLGFQQNRMDNKLDEKYIDYTYHSELSALLFIDIEYNNIKEYTFSNNRKQNNQTKTLIKDVLLRLSFLIKCHHTGLYNFDKIGYIEDLKILQDKINNNPKIIKYYDKDNINIDFSGFGSYEYKEDNLIQYVFYKFLYSILITCDSFATHHFFINNEVELSLFDEKLIKECNNKYQSTDIYKNISNYKKDNNYFEDTNINKTRCDIFLETEENLTHNLDKNIYFLEACTGSGKTNISQNLALQLLINNKTLNKIIYTFPFNTLIEQTKGVLYNNFSEANVDIVAINSIEEIKNNDEDYDNDLLKYQFLQYPITLTSHINLFSILFGYGRRGNLAFSQICNSVIILDEIQSYNHLLWNKMIEIFNILSEFLNVKFVIMSATLPTLDLFLEECKRDSVCKLINDTKRYYDNPIFKERVSIDFSMLENESITIDDVENKIDDIIKDDTKGNRILVEFITVNSADEMYDRIKSKYNDDFLVFELTNQDNQLYRKYVINKLNEKDDKGDFKNKNVVVISTQVIEAGVDIDMEVGLKDISILESEEQFLGRINRNGKDKGYAYFFSMDKTKNTYRGDFRVSYDLKNEDIQQCLTNKDFTQYYLKCINHLKDESQKQGNNNLNEFNDNLVNIKFKAISESMKLIENKSVQLYLIYKYKTKDGKIINSADILEEYKELKSIPSYAERMIKESKLKKDMNLFTYNFNIYDDKYPQIYSDIINNSLYIVENGQEYMEDTEEQYIVFKSKFNLKKYS
>NC_015417.1|WP_039244034.1|30547_31141_+|IS607-like-element-ISCbo10-family-transposase
MKSKEVLELLQITRPTLTKYVKEGIIKTITLPNGRYDYNQEDVFKLFNKGVERKTYIYARVSTPKQKKDLENQVQLLKQFCFSNGWMINNVFQDVASGISFDKRKDFFKMLDDIIQNKVERVVITYKDRLSRVGFELFYYLFKKYHCEIVVMSEIGSEKLDSQEVFEEIVSLLHCYSMKMYSKRKCNKIKEVLQEED
>NC_015417.1|WP_013720791.1|31177_32590_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MTTKKDDNTVQRVEKHMINQNHELYELLNHYTFLSKNLYNYANYQLRQVFILTSKLKEDEELTTEQHEYLNSINAKVNEFNELRKVNFEKAKQRAIKQGKELNKKLKLINYFNEDNKYLGYDFLEFLLKDGIDYKSLMSQVSQQTLKLLDKNWISFFESIKDWSKHKEKYNGRPKLPKYKKKNGKNILVFTNQNCKQKKGYIQFPKCFNKYELKTNINGNLQQVRILPRNKHYVIEVVYKIEKKEKLNDNGKYISIDIGLDNFATVVNNIGLKPIIINGKGLKSINKYYNKKLSYYKEIAKRMNNLDYTNRMNRLTIKRNNKIIDFVHKASKKVIDYALANNINTIIVGNNKDWKRESNMSKVVNQSFVGIPHQEFINKLIYKCENVGLNIIITEESYTSGTSFLDNELPNKENYNKKRRVYRGLFVSNNGVKINADVNGAYQIMRKVLSNVKADEIEGVGLHPIRVNIA
>NC_015417.1|WP_013720792.1|33135_33807_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MLRSIEALKEIQRRMEVRRGDVWMVEIPQEAKEVFGSNIQTGLRPCIIISGEGNNKHANIVNILPISSKINKVYPQHTEITTYEDLRDCGLTKRSIVLSEQMMTIDKSKLIDKLGRANDKLMQRVEKGLEVQQGKNLRCVKRDNVRNFNKERFSFKKAFDKIEMINKAKDLDAELYMYLYGELKEYCEDHNVKYYEVINKYNNIKDRFKFNPTIMNNMVAMGY
>NC_015417.1|WP_013720793.1|34256_35663_+|hypothetical-protein
MKIKSRDELGKNKNEIDKLLEQELPKMYALYPKMVYDVAEQLEDKNITIGTISGLFGGITPTYKLEEVDELGSFLKAIYEVGTKYSKNKILIIPNLEKLNPENFYTETEINSINLYKKEVSKENNIIKLYVRKNAENHYVCPYISMVEYVDYYKRGLIIYNPNTQRETTKKMVKGQINEFITIHQENVNKIYNDLKNDRFNPNMLTLNIRDNEGDDPQFDDGGMNVGDFGWLKIKVDGRQHSYVDLLDGQHRTSAQEIYVEEYPNTDKYNMLNVFVFNEEQAIHHIIQENSGTKIDENSLQRRDPDNKGVAMAKELKTLSKELKGKVANDLIELTKHCQYTDVLTLGSAINNYFDIDGRKEYREIRSYLSKFFDVAIDCYKDYFNKRNLQPKELFYRKNTFIAFCDIAKKLYKFKDWEDKAFDIFEKLSIEEIESVSGNKKILKPNDYKIISNKLQKSLAEREVAIDG
>NC_015417.1|WP_013720794.1|35655_36750_+|site-specific-integrase
MANVKQYKRRFVVTEEMYNEDVKNRFIDYYYDNEQTKLNIKRTFYLTNFYMEKDLDKDIYNFNKYEIESLLKSFKATSEGSLAVRLTHIKKYIDFCISMGIRSNAINFCDTIANLKDYVVRNLDKYKYITREQLYNICDIMESSQIAVIFILFFEGIVGKEKCEMRNLKVEDVDFDNNSITIRAYDEINPRTGEIIHKPERILTNVHPRTMEYIKDAIEETVMIMPESKLFTDPEKDVAIKTGKIGKNPAPHYVVQNDYVVRKSSRKLKSDEEEENTPISMSTIINRIYYATDYFVDDENLYFVKKLNTTTLEQSGMIEELEKIEAQKGKLVVQDFKDVIASRNKRTYHSLKRLWDAIKKEKSE
>NC_015417.1|WP_013720795.1|36831_37215_+|hypothetical-protein
MGKILSKELIINGVKEREIEFEKMKNKLDDTSTILSDYRNIVLRKRKLENELQLREFEENFNNKDMDKLKSNFEILDLIHKTNLTVNKILHIMQSNNWTIKDIYKEYEKGYTRNILALLSKSNKNIC
>NC_015417.1|WP_013720796.1|37272_39222_+|NAD-dependent-DNA-ligase-LigA
MEDKTQRVKELIKELNQASDKYYNSDETVMTDKEWDDKFDKLKQLEQDTGIILSNSPTQKVGYEVKSKLDKVVHNIPLKSLGKTKSIGDLNKFIGSNEVIIMDKGDGLTCELIYENGQLLQGSTRGNGEIGEDITHNVKTFKNIPLQIDFKGYLKLSGESVILDEDFELINSKLDDEDKYSNSRNLVAGSVRQLDSNICDKRNVKFYAFSLLECEGVDFITKEEQLEFLSRLGFETIEYIKYNNSEDLEQVISKMQKSAYEKGFPIDGLVFAYNNIEYANLLGDTLHHPLHSIAYKFYDEEYETQYITTEWQVSRTGMINPVARFKPVEIEGSVVERATLHNLDYFEDLKLGQGDTIKVIKANQVIPKVMSNDTMSNTEIIPTECPVCGGKTEEKLLKTARVLICNNPECSAKHISRITHYCSRNAMNIDGLSEKTIEKFVNLGYLKDIDDIYKLEQYKEEIINIDGLGTKSYNNMIEAIEKSKYCKLENFIFALGVPNVGLGTAKLLVKQFKSIDKIMNCNLTEIYGIEGIGDVVGSEIYNYFIINTDSINLVNKLLKFIDFEEVKESSSNKLEGKTFVITGDVHVFKNRNEVKAKIEEMGGKVTGSVSKKTDYLINNDVESTSSKNQKAKDLNIPIITEEEFVEMIK
>NC_015417.1|WP_019279003.1|39319_39601_+|hypothetical-protein
MLNNIIKVEDYEVEVGDVDWELTSRYILSRELIITVKKNNEVVLSSKGKLKSEFFNYLGFLINDKGVLKTIEQIYDNPNNFLLENYELENGFF
>NC_015417.1|WP_013720798.1|39632_40061_+|hypothetical-protein
MLGLKYLDKFIPILKGKLLKNNTYTRELNYRGESKYNKKETWYNLRYGVYKYYIYNVKGNENCTYKEVMKKLSSNALSGVKMPDDREGVEVYRYGNMAIKVKNNEIVYICNNKGIGSFERYKFNVDTKYRDYLRKLWRIDDL

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Crispr_ID: NC_015417_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015417_4

202986-203097

Orphan

Consensus_repeat	Method
AAAGTATTGATATATAAGGGTTTGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015417_4

>merge|NC_015417|4|202986-203097|CRISPRCasFinder
AAAGTATTGATATATAAGGGTTTGCGGGGTGTCAATGATATGCAAATTTTTAATGATGAGATGAGTTAAGATAGGTAATATCGTTCAAAGTATTGATACATAAGGGTTTGCG

>NC_015417|4|4|202986-203097|CRISPRCasFinder
AAAGTATTGATATATAAGGGTTTGCG	GGGTGTCAATGATATGCAAATTTTTAATGATGAGATGAGTTAAGATAGGTAATATCGTTC
AAAGTATTGATACATAAGGGTTTGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015417.1\|WP_003367553.1\|197287_197464_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_003367529.1\|195752_195998_-\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_003367525.1\|201095_201284_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_013720965.1\|201628_201847_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_003367566.1\|196495_196879_-\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|377369
NC_015417.1\|WP_013720966.1\|202395_202851_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_003367551.1\|200712_200955_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_003367523.1\|201304_201616_+\|hypothetical-protein	unknown	unknown	unknown
NC_015417.1\|WP_039244068.1\|197476_199363_+\|cell-division-protein-FtsK	unknown	unknown	gnl\|CDD\|224588
NC_015417.1\|WP_013720964.1\|199366_199984_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197670

>NC_015417.1|WP_013720966.1|202395_202851_+|hypothetical-protein
MNNKNIEQIPFIIQELYSIVSVLESSFKGRKFTPYGHLAGSIGEVLASYYYDLELLPCSTKTHAAKTKDNKLVKIKVTQGKSIGISSKPDYLIVIKILPDGSIEEIYNGSGYLAWHNTGKTQRNGQRSISINKLNKLMEDMPINLRIPRVK
>NC_015417.1|WP_013720965.1|201628_201847_+|hypothetical-protein
MLNRCKTYEFSKKGWKQAKQDSKKIKNNRVMDLIVYSTLLGLTVGNIVKNDTFLKIVACDGTKRVVKTLIIH
>NC_015417.1|WP_003367523.1|201304_201616_+|hypothetical-protein
MVGDIFSDIIKTATLTIVWNKGLQAFGKKDYGEIIKLSGISVCGIDVIQLVSYWRKNPPAIVRIVKGTANFFEKVDNGTGKIMDGIGKFNESIKFLIDRGIVK
>NC_015417.1|WP_003367525.1|201095_201284_+|hypothetical-protein
MSNTAIIIAMGSTAIVSAITEKVLIAFNKQNESQMVNIGGLSLVGCQAVLLVTKLIKACSAL
>NC_015417.1|WP_003367551.1|200712_200955_+|hypothetical-protein
MKNIIQITHSTLRLSIKLTIRQLKFINKLIYKANNYKSTIKTNVNTKQYQQEICTYNEKVANGTSNIVDLRSYIKQQKEY
>NC_015417.1|WP_013720964.1|199366_199984_+|hypothetical-protein
MLVKLTGKYDKAILRYIEQSRFCTAKQIAKIFYKTSSQGEALARRRLNRMIEAQYLRVYRSKSFDNRNVYVFDTKANKSLKPSLHDMTILDYQAELIYSGADIIYFKPNQYWMDGKIRSDGFCVFKFNNKIYYNLIEVVVNHNDDKFKKYDDLYVTNEVQNICENEFPELIIIDSLTHKTNFKFEQNIKFKVIDLELNDFPKIFL
>NC_015417.1|WP_039244068.1|197476_199363_+|cell-division-protein-FtsK
MKFVFMHIKNKKLTQQNKNKMIDIGKSQIVVRDRKEIGKSLLKQPKYEIIESNTINKLSIKDKLSDIKSKLKEEYRKNKEIQYLNERWLDVMFNCKFINAFKKTFTLVNLKHENYGFSCRILIPDGYCIDDLDNKTTVIQNNVGCTFVLEKFSNKRYANAKFILIENCNKIPFKPVEVEPYQVCAGVDEGGHPVIFNMNIEPMVLIAGATRMGKNGCIDHAIPSWIYYCSEDDIHLYLFQFAKGDLGKYQKCKQVKCFSMSDLDKLLEVLNELKTEMSARMNMMSSMLNNFKGDNLYDYNKLNPDKKLPYIYIIIDEFMDIANSEGDKEYSKVKAHIISILQSIAEYGGALGVNYIILHQKPEKSLMPTFLKNQSNTRICFGFKDEVCGRIVLGEDRGKLVTTLQPRKAYYVSNSGEGYLYTTNLRNKNGSSRILNYIKPSMTNKKESSNVHHVSDCKVAKNDKYSKSKDSEVQFKEKVSQIKIQMDKINKHSKNSEDTPQSKGKIIEFPNQYNQDNSHHNLDATHTSNPTSQNKKYDIKITQSNNKSTSNKPIQNPNIDSNFSKVNIPKVKSKEDVIRENIKKIPNFVPYEPPKTNAKITDETDIAFKQSEKYRKDIKNENDKKGDY
>NC_015417.1|WP_003367553.1|197287_197464_+|hypothetical-protein
MPYGLLIGGWSIGMICYISLTKIGNKNNFKYADLTSRIKKAKRLDKNISKSLEDKNLF
>NC_015417.1|WP_003367566.1|196495_196879_-|restriction-endonuclease
MSPREFEVFVANLFTQLGYNAKATVETCDGGKDVIATNNKEKIYIECKHWNMNNLIGREILQKLVGSAIGDDATRAIVITTSKYNKNALEYAEKVPWLELWTMKDIIKALNKIEDNKKGYVVNCLEG
>NC_015417.1|WP_003367529.1|195752_195998_-|hypothetical-protein
MAVNKNEYKILIMLKENQCTTELKSFTYTKLCKISELSMSTVRRSIKKFLELQYVKEGCKQGISKTFYITPNGIEKLKSIM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_015417_1	1.10\|17425\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17425-17460	36	NC_015427.1	6245-6280	1	0.972

1. spacer 1.10|17425|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to position: 6245-6280, mismatch: 1, identity: 0.972

tgaagcaagaagaaagaagcgaatttataaaagagt	CRISPR spacer
tggagcaagaagaaagaagcgaatttataaaagagt	Protospacer
**.*********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015417_1	1.1\|16832\|37\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	16832-16868	37	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	16832-16868	0	1.0
NC_015417_1	1.2\|16899\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	16899-16933	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	16899-16933	0	1.0
NC_015417_1	1.3\|16964\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	16964-16998	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	16964-16998	0	1.0
NC_015417_1	1.4\|17029\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17029-17064	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17029-17064	0	1.0
NC_015417_1	1.5\|17095\|37\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17095-17131	37	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17095-17131	0	1.0
NC_015417_1	1.6\|17162\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17162-17197	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17162-17197	0	1.0
NC_015417_1	1.7\|17228\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17228-17263	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17228-17263	0	1.0
NC_015417_1	1.8\|17294\|34\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17294-17327	34	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17294-17327	0	1.0
NC_015417_1	1.9\|17358\|37\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17358-17394	37	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17358-17394	0	1.0
NC_015417_1	1.10\|17425\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17425-17460	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17425-17460	0	1.0
NC_015417_1	1.11\|17491\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17491-17526	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17491-17526	0	1.0
NC_015417_1	1.12\|17557\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17557-17591	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17557-17591	0	1.0
NC_015417_1	1.13\|17622\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17622-17657	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17622-17657	0	1.0
NC_015417_1	1.14\|17688\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17688-17723	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17688-17723	0	1.0
NC_015417_1	1.15\|17754\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17754-17789	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17754-17789	0	1.0
NC_015417_1	1.16\|17820\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17820-17854	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17820-17854	0	1.0
NC_015417_1	1.17\|17885\|37\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17885-17921	37	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17885-17921	0	1.0
NC_015417_1	1.18\|17952\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17952-17986	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	17952-17986	0	1.0
NC_015417_1	1.19\|18017\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	18017-18052	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	18017-18052	0	1.0
NC_015417_1	1.20\|18083\|36\|NC_015417\|CRISPRCasFinder,CRT	18083-18118	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	18083-18118	0	1.0
NC_015417_2	2.1\|25091\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25091-25125	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25091-25125	0	1.0
NC_015417_2	2.2\|25156\|38\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25156-25193	38	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25156-25193	0	1.0
NC_015417_2	2.3\|25224\|37\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25224-25260	37	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25224-25260	0	1.0
NC_015417_2	2.4\|25291\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25291-25326	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25291-25326	0	1.0
NC_015417_2	2.5\|25357\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25357-25392	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25357-25392	0	1.0
NC_015417_2	2.6\|25423\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25423-25458	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25423-25458	0	1.0
NC_015417_2	2.7\|25489\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25489-25524	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25489-25524	0	1.0
NC_015417_2	2.8\|25555\|35\|NC_015417\|CRISPRCasFinder,CRT	25555-25589	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	25555-25589	0	1.0
NC_015417_3	3.1\|27145\|35\|NC_015417\|CRISPRCasFinder,CRT	27145-27179	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27145-27179	0	1.0
NC_015417_3	3.2\|27210\|36\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27210-27245	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27210-27245	0	1.0
NC_015417_3	3.3\|27276\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27276-27309	34	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27276-27309	0	1.0
NC_015417_3	3.4\|27340\|36\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27340-27375	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27340-27375	0	1.0
NC_015417_3	3.5\|27406\|36\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27406-27441	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27406-27441	0	1.0
NC_015417_3	3.6\|27472\|35\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27472-27506	35	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27472-27506	0	1.0
NC_015417_3	3.7\|27537\|37\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27537-27573	37	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27537-27573	0	1.0
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27604-27637	0	1.0
NC_015417_3	3.9\|27668\|37\|NC_015417\|CRISPRCasFinder,CRT	27668-27704	37	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27668-27704	0	1.0
NC_015417_3	3.10\|27735\|36\|NC_015417\|CRISPRCasFinder,CRT	27735-27770	36	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27735-27770	0	1.0
NC_015417_3	3.11\|27801\|34\|NC_015417\|CRISPRCasFinder	27801-27834	34	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27801-27834	0	1.0
NC_015417_3	3.12\|27865\|31\|NC_015417\|CRISPRCasFinder	27865-27895	31	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	27865-27895	0	1.0
NC_015417_4	4.1\|203012\|60\|NC_015417\|CRISPRCasFinder	203012-203071	60	NC_015417	Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence	203012-203071	0	1.0
NC_015417_1	1.10\|17425\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17425-17460	36	NC_015427	Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence	6245-6280	1	0.972
NC_015417_2	2.7\|25489\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25489-25524	36	NC_015427	Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence	13112-13147	4	0.889
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NC_016770	Bacteroides phage B124-14, complete genome	29683-29716	6	0.824
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	HE608841	Bacteroides phage B124-14 complete genome	29683-29716	6	0.824
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	MT630433	Bacteroides phage vB_BfrS_23, complete genome	32925-32958	6	0.824
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	MN078104	Bacteroides phage Barc2635, complete genome	35442-35475	6	0.824
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	FJ008913	Bacteroides phage B40-8 culture-collection ATCC:51477-B1, complete genome	39802-39835	6	0.824
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NC_011222	Bacteroides phage B40-8, complete genome	39802-39835	6	0.824
NC_015417_3	3.3\|27276\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27276-27309	34	NZ_CP026534	Bacillus velezensis strain DKU_NT_04 plasmid p1_DKU_NT_04, complete sequence	127058-127091	7	0.794
NC_015417_3	3.3\|27276\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27276-27309	34	NZ_CP032858	Bacillus subtilis subsp. subtilis strain 2RL2-3 plasmid unnamed1, complete sequence	4361-4394	7	0.794
NC_015417_3	3.3\|27276\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27276-27309	34	NZ_CP032873	Bacillus subtilis subsp. subtilis strain 2KL1 plasmid unnamed1, complete sequence	25394-25427	7	0.794
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NC_028820	Yersinia phage vB_YenM_TG1, complete genome	107885-107918	7	0.794
NC_015417_1	1.3\|16964\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	16964-16998	35	NC_015427	Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence	9763-9797	8	0.771
NC_015417_1	1.14\|17688\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17688-17723	36	NZ_CP026601	Clostridiaceae bacterium 14S0207 plasmid unnamed1, complete sequence	19421-19456	8	0.778
NC_015417_1	1.16\|17820\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17820-17854	35	NZ_CP030224	Salmonella enterica strain SA20083039 plasmid pSA20083039.1, complete sequence	37610-37644	8	0.771
NC_015417_2	2.4\|25291\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25291-25326	36	MK813939	Aeromonas phage 4_L372D, complete genome	106423-106458	8	0.778
NC_015417_2	2.4\|25291\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25291-25326	36	MK804893	Aeromonas phage 2-L372D, complete genome	97728-97763	8	0.778
NC_015417_2	2.4\|25291\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25291-25326	36	NC_048770	Aeromonas phage 2_L372X, complete genome	95264-95299	8	0.778
NC_015417_2	2.4\|25291\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25291-25326	36	MK813941	Aeromonas phage 4_L372XY, complete genome	97175-97210	8	0.778
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NZ_CP023672	Clostridium septicum strain DSM 7534 plasmid unnamed1, complete sequence	2614-2647	8	0.765
NC_015417_3	3.12\|27865\|31\|NC_015417\|CRISPRCasFinder	27865-27895	31	NC_018492	Bacillus cereus FRI-35 plasmid p01, complete sequence	64887-64917	8	0.742
NC_015417_3	3.12\|27865\|31\|NC_015417\|CRISPRCasFinder	27865-27895	31	NC_011973	Bacillus cereus Q1 plasmid pBc239, complete sequence	203521-203551	8	0.742
NC_015417_1	1.16\|17820\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17820-17854	35	MN693579	Marine virus AFVG_25M167, complete genome	9709-9743	9	0.743
NC_015417_1	1.16\|17820\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17820-17854	35	MN693244	Marine virus AFVG_25M166, complete genome	24334-24368	9	0.743
NC_015417_1	1.16\|17820\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17820-17854	35	AP013387	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C42-MedDCM-OCT-S29-C52	19452-19486	9	0.743
NC_015417_2	2.7\|25489\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	25489-25524	36	NZ_CP031074	Bacillus mycoides strain BPN401 plasmid pl41, complete sequence	17075-17110	9	0.75
NC_015417_3	3.3\|27276\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27276-27309	34	MN694354	Marine virus AFVG_250M116, complete genome	22293-22326	9	0.735
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NZ_CP015920	Pediococcus pentosaceus strain wikim20 plasmid pKPP02, complete sequence	9913-9946	9	0.735
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NZ_CP029731	Citrobacter sp. CRE-46 strain AR_0157 plasmid unnamed3, complete sequence	7287-7320	9	0.735
NC_015417_1	1.10\|17425\|36\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17425-17460	36	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	40043-40078	10	0.722
NC_015417_1	1.12\|17557\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17557-17591	35	NZ_AP018283	Chondrocystis sp. NIES-4102 plasmid plasmid2 DNA, complete genome	12150-12184	10	0.714
NC_015417_1	1.16\|17820\|35\|NC_015417\|PILER-CR,CRISPRCasFinder,CRT	17820-17854	35	MT773556	Myoviridae sp. isolate BML_4 genomic sequence	179261-179295	10	0.714
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NZ_CP046399	Bacillus sp. A260 plasmid unnamed11, complete sequence	149060-149093	10	0.706
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	AP013406	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S46-C34	33603-33636	10	0.706
NC_015417_3	3.8\|27604\|34\|NC_015417\|CRISPRCasFinder,CRT,PILER-CR	27604-27637	34	NZ_AP019741	Acinetobacter radioresistens DSM 6976 = NBRC 102413 = CIP 103788 strain NBRC 102413 plasmid pARA1, complete sequence	184709-184742	10	0.706

1. spacer 1.1|16832|37|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gctttgaaagcttgtcccgaatagcttgtacacttat	CRISPR spacer
gctttgaaagcttgtcccgaatagcttgtacacttat	Protospacer
*************************************

2. spacer 1.2|16899|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gaaacacagtttaaaacaaatttggaagttggaat	CRISPR spacer
gaaacacagtttaaaacaaatttggaagttggaat	Protospacer
***********************************

3. spacer 1.3|16964|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

agctaaaaagaatggtgaataccttcctgaaatta	CRISPR spacer
agctaaaaagaatggtgaataccttcctgaaatta	Protospacer
***********************************

4. spacer 1.4|17029|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gaattaataaaattaatacaagacaatacaatggaa	CRISPR spacer
gaattaataaaattaatacaagacaatacaatggaa	Protospacer
************************************

5. spacer 1.5|17095|37|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

aaatttgccatatgcggtccccaaagtacccatttac	CRISPR spacer
aaatttgccatatgcggtccccaaagtacccatttac	Protospacer
*************************************

6. spacer 1.6|17162|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

aaacctacatgatgatatatggaaagtagagcttat	CRISPR spacer
aaacctacatgatgatatatggaaagtagagcttat	Protospacer
************************************

7. spacer 1.7|17228|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

aagtaagcttttccagtaactccccttacttttaat	CRISPR spacer
aagtaagcttttccagtaactccccttacttttaat	Protospacer
************************************

8. spacer 1.8|17294|34|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ttagtgccatagtttgtactccaaatatctaaac	CRISPR spacer
ttagtgccatagtttgtactccaaatatctaaac	Protospacer
**********************************

9. spacer 1.9|17358|37|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ataaaaatttaagataaatttaagggaagacactaat	CRISPR spacer
ataaaaatttaagataaatttaagggaagacactaat	Protospacer
*************************************

10. spacer 1.10|17425|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcaagaagaaagaagcgaatttataaaagagt	CRISPR spacer
tgaagcaagaagaaagaagcgaatttataaaagagt	Protospacer
************************************

11. spacer 1.11|17491|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttgcttgtctttgtttttctctaacatactcctgt	CRISPR spacer
tttgcttgtctttgtttttctctaacatactcctgt	Protospacer
************************************

12. spacer 1.12|17557|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tctattaaagattttaaagcaagattttcgcttat	CRISPR spacer
tctattaaagattttaaagcaagattttcgcttat	Protospacer
***********************************

13. spacer 1.13|17622|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

aggtaaagaacaagacgatgagggatattttagaga	CRISPR spacer
aggtaaagaacaagacgatgagggatattttagaga	Protospacer
************************************

14. spacer 1.14|17688|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttgtaactgtaaaatcatttaactttttaatatct	CRISPR spacer
tttgtaactgtaaaatcatttaactttttaatatct	Protospacer
************************************

15. spacer 1.15|17754|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tgtgatagagtagcatttaaatataaggttctaggt	CRISPR spacer
tgtgatagagtagcatttaaatataaggttctaggt	Protospacer
************************************

16. spacer 1.16|17820|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

acatctaatatagtaatagtcttttctttatcgtt	CRISPR spacer
acatctaatatagtaatagtcttttctttatcgtt	Protospacer
***********************************

17. spacer 1.17|17885|37|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

agaattacgaagacagtatgagaatgctagagaactt	CRISPR spacer
agaattacgaagacagtatgagaatgctagagaactt	Protospacer
*************************************

18. spacer 1.18|17952|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttgacaagcctgttttttatccatttttgacatt	CRISPR spacer
tttgacaagcctgttttttatccatttttgacatt	Protospacer
***********************************

19. spacer 1.19|18017|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gaaatcggttgtccttttgtataatctcttaatcca	CRISPR spacer
gaaatcggttgtccttttgtataatctcttaatcca	Protospacer
************************************

20. spacer 1.20|18083|36|NC_015417|CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ttttgttttgttcagtatctttttttgggagttcct	CRISPR spacer
ttttgttttgttcagtatctttttttgggagttcct	Protospacer
************************************

21. spacer 2.1|25091|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tgtgttattcaaagcacacccaaatagcgaattat	CRISPR spacer
tgtgttattcaaagcacacccaaatagcgaattat	Protospacer
***********************************

22. spacer 2.2|25156|38|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttaaattgttaaaatattttttaagttcattttatga	CRISPR spacer
tttaaattgttaaaatattttttaagttcattttatga	Protospacer
**************************************

23. spacer 2.3|25224|37|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ttaagtatattccattttgatgaaaaacaagcaatac	CRISPR spacer
ttaagtatattccattttgatgaaaaacaagcaatac	Protospacer
*************************************

24. spacer 2.4|25291|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

caagaagaaataacttttgaagataaagaagattta	CRISPR spacer
caagaagaaataacttttgaagataaagaagattta	Protospacer
************************************

25. spacer 2.5|25357|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

caatgaagaaatgaaagcatccaccaatgagtatac	CRISPR spacer
caatgaagaaatgaaagcatccaccaatgagtatac	Protospacer
************************************

26. spacer 2.6|25423|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ttgagtgaaagatggaatgtgtttaaaataaatgag	CRISPR spacer
ttgagtgaaagatggaatgtgtttaaaataaatgag	Protospacer
************************************

27. spacer 2.7|25489|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gcaagggattattataagaaaaataaatgtgatatt	CRISPR spacer
gcaagggattattataagaaaaataaatgtgatatt	Protospacer
************************************

28. spacer 2.8|25555|35|NC_015417|CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gatattgaaagtggaagagtaattaaagtttggac	CRISPR spacer
gatattgaaagtggaagagtaattaaagtttggac	Protospacer
***********************************

29. spacer 3.1|27145|35|NC_015417|CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

attagtttaccacactttggacacattctcattag	CRISPR spacer
attagtttaccacactttggacacattctcattag	Protospacer
***********************************

30. spacer 3.2|27210|36|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ccgatagtgtattctttaccttcaaattctacttta	CRISPR spacer
ccgatagtgtattctttaccttcaaattctacttta	Protospacer
************************************

31. spacer 3.3|27276|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

atataatcttttttatggaggtgatacacttgat	CRISPR spacer
atataatcttttttatggaggtgatacacttgat	Protospacer
**********************************

32. spacer 3.4|27340|36|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tgtttagctaggtagttttgataaactttagtattc	CRISPR spacer
tgtttagctaggtagttttgataaactttagtattc	Protospacer
************************************

33. spacer 3.5|27406|36|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tgaaattgagaataagcaaaaatcaattcttgtaac	CRISPR spacer
tgaaattgagaataagcaaaaatcaattcttgtaac	Protospacer
************************************

34. spacer 3.6|27472|35|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tctgtactctcttctatagtcatttttaatagtgt	CRISPR spacer
tctgtactctcttctatagtcatttttaatagtgt	Protospacer
***********************************

35. spacer 3.7|27537|37|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

catttatatggttcttgcttgtccgattgactttata	CRISPR spacer
catttatatggttcttgcttgtccgattgactttata	Protospacer
*************************************

36. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tcgtaattgttaattattatttcaattttcttat	Protospacer
**********************************

37. spacer 3.9|27668|37|NC_015417|CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tataagtatagtgattttaaaaatattgatgatctag	CRISPR spacer
tataagtatagtgattttaaaaatattgatgatctag	Protospacer
*************************************

38. spacer 3.10|27735|36|NC_015417|CRISPRCasFinder,CRT matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

aaagtagttattttgaaacttataaatacattaatc	CRISPR spacer
aaagtagttattttgaaacttataaatacattaatc	Protospacer
************************************

39. spacer 3.11|27801|34|NC_015417|CRISPRCasFinder matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

taatttgcatatgttaaaatagaaataaatgtag	CRISPR spacer
taatttgcatatgttaaaatagaaataaatgtag	Protospacer
**********************************

40. spacer 3.12|27865|31|NC_015417|CRISPRCasFinder matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

atatttagttttaattcgcaaggattagtat	CRISPR spacer
atatttagttttaattcgcaaggattagtat	Protospacer
*******************************

41. spacer 4.1|203012|60|NC_015417|CRISPRCasFinder matches to NC_015417 (Clostridium botulinum BKT015925 plasmid p1BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gggtgtcaatgatatgcaaatttttaatgatgagatgagttaagataggtaatatcgttc	CRISPR spacer
gggtgtcaatgatatgcaaatttttaatgatgagatgagttaagataggtaatatcgttc	Protospacer
************************************************************

42. spacer 1.10|17425|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015427 (Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence) position: , mismatch: 1, identity: 0.972

tgaagcaagaagaaagaagcgaatttataaaagagt	CRISPR spacer
tggagcaagaagaaagaagcgaatttataaaagagt	Protospacer
**.*********************************

43. spacer 2.7|25489|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015427 (Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence) position: , mismatch: 4, identity: 0.889

gcaagggattattataagaaaaataaatgtgatatt	CRISPR spacer
gccgagaattattataagaaaaataaatgtgatatt	Protospacer
** ..*.*****************************

44. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_016770 (Bacteroides phage B124-14, complete genome) position: , mismatch: 6, identity: 0.824

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tttaaagtgttaataattatttcaattttctttt	Protospacer
*.  ** ******* ***************** *

45. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to HE608841 (Bacteroides phage B124-14 complete genome) position: , mismatch: 6, identity: 0.824

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tttaaagtgttaataattatttcaattttctttt	Protospacer
*.  ** ******* ***************** *

46. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to MT630433 (Bacteroides phage vB_BfrS_23, complete genome) position: , mismatch: 6, identity: 0.824

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tttaaagtgttaataattatttcaattttctttt	Protospacer
*.  ** ******* ***************** *

47. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to MN078104 (Bacteroides phage Barc2635, complete genome) position: , mismatch: 6, identity: 0.824

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tttaaagtgttaataattatttcaattttctttt	Protospacer
*.  ** ******* ***************** *

48. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to FJ008913 (Bacteroides phage B40-8 culture-collection ATCC:51477-B1, complete genome) position: , mismatch: 6, identity: 0.824

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tttaaagtgttaataattatttcaattttctttt	Protospacer
*.  ** ******* ***************** *

49. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_011222 (Bacteroides phage B40-8, complete genome) position: , mismatch: 6, identity: 0.824

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tttaaagtgttaataattatttcaattttctttt	Protospacer
*.  ** ******* ***************** *

50. spacer 3.3|27276|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026534 (Bacillus velezensis strain DKU_NT_04 plasmid p1_DKU_NT_04, complete sequence) position: , mismatch: 7, identity: 0.794

atataatcttttttatggaggtga---tacacttgat	CRISPR spacer
acataatctttttgatggagctgatagtacactc---	Protospacer
*.*********** ****** ***   ******.

51. spacer 3.3|27276|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032858 (Bacillus subtilis subsp. subtilis strain 2RL2-3 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

atataatcttttttatggaggtga---tacacttgat	CRISPR spacer
acataatctttttgatggagctgatagtacactc---	Protospacer
*.*********** ****** ***   ******.

52. spacer 3.3|27276|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032873 (Bacillus subtilis subsp. subtilis strain 2KL1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

atataatcttttttatggaggtga---tacacttgat	CRISPR spacer
acataatctttttgatggagctgatagtacactc---	Protospacer
*.*********** ****** ***   ******.

53. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NC_028820 (Yersinia phage vB_YenM_TG1, complete genome) position: , mismatch: 7, identity: 0.794

tcgtaattg--ttaattattatttcaattttcttat	CRISPR spacer
--gtaacagatttaaatattaattcaattttcttac	Protospacer
  ****. *  **** ***** *************.

54. spacer 1.3|16964|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_015427 (Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence) position: , mismatch: 8, identity: 0.771

agctaaaaagaatggtgaataccttcctgaaatta	CRISPR spacer
aagcaaaaaaaatggtgaataccttccagaggtaa	Protospacer
*. .*****.***************** **..* *

55. spacer 1.14|17688|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026601 (Clostridiaceae bacterium 14S0207 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

tttgtaactgtaaaatcatttaactttttaatatct	CRISPR spacer
tagttaagattaaaatcattaaactttttactatct	Protospacer
*   ***   ********** ********* *****

56. spacer 1.16|17820|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030224 (Salmonella enterica strain SA20083039 plasmid pSA20083039.1, complete sequence) position: , mismatch: 8, identity: 0.771

acatctaatatagtaatagtcttttctttatcgtt	CRISPR spacer
acatctaatatattaattgtcttttttctcgctgt	Protospacer
************ **** *******.*.*  *  *

57. spacer 2.4|25291|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to MK813939 (Aeromonas phage 4_L372D, complete genome) position: , mismatch: 8, identity: 0.778

caagaagaaataacttttgaagataaagaagattta	CRISPR spacer
caagaagataaaacttttgaagataatctaaatgtt	Protospacer
******** * ***************   *.** *

58. spacer 2.4|25291|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to MK804893 (Aeromonas phage 2-L372D, complete genome) position: , mismatch: 8, identity: 0.778

caagaagaaataacttttgaagataaagaagattta	CRISPR spacer
caagaagataaaacttttgaagataatctaaatgtt	Protospacer
******** * ***************   *.** *

59. spacer 2.4|25291|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_048770 (Aeromonas phage 2_L372X, complete genome) position: , mismatch: 8, identity: 0.778

caagaagaaataacttttgaagataaagaagattta	CRISPR spacer
caagaagataaaacttttgaagataatctaaatgtt	Protospacer
******** * ***************   *.** *

60. spacer 2.4|25291|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to MK813941 (Aeromonas phage 4_L372XY, complete genome) position: , mismatch: 8, identity: 0.778

caagaagaaataacttttgaagataaagaagattta	CRISPR spacer
caagaagataaaacttttgaagataatctaaatgtt	Protospacer
******** * ***************   *.** *

61. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023672 (Clostridium septicum strain DSM 7534 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
tatgaaagcttaatttttatttcaatttttttat	Protospacer
*   **   ****** *************.****

62. spacer 3.12|27865|31|NC_015417|CRISPRCasFinder matches to NC_018492 (Bacillus cereus FRI-35 plasmid p01, complete sequence) position: , mismatch: 8, identity: 0.742

atatttagttttaattcgcaaggattagtat	CRISPR spacer
gttgctggttttaattcggaagtattagtaa	Protospacer
.*  .*.*********** *** *******

63. spacer 3.12|27865|31|NC_015417|CRISPRCasFinder matches to NC_011973 (Bacillus cereus Q1 plasmid pBc239, complete sequence) position: , mismatch: 8, identity: 0.742

atatttagttttaattcgcaaggattagtat	CRISPR spacer
gttgctggttttaattcggaagtattagtaa	Protospacer
.*  .*.*********** *** *******

64. spacer 1.16|17820|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to MN693579 (Marine virus AFVG_25M167, complete genome) position: , mismatch: 9, identity: 0.743

acatctaatatagtaatagtcttttctttatcgtt	CRISPR spacer
tcatctactctagtaatagtcttttcaagatcaga	Protospacer
 ****** * ****************   ***.

65. spacer 1.16|17820|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to MN693244 (Marine virus AFVG_25M166, complete genome) position: , mismatch: 9, identity: 0.743

acatctaatatagtaatagtcttttctttatcgtt	CRISPR spacer
tcatctactctagtaatagtcttttcaagatcaga	Protospacer
 ****** * ****************   ***.

66. spacer 1.16|17820|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to AP013387 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-C42-MedDCM-OCT-S29-C52) position: , mismatch: 9, identity: 0.743

acatctaatatagtaatagtcttttctttatcgtt	CRISPR spacer
tcatctactctagtaatagtcttttcaagatcaga	Protospacer
 ****** * ****************   ***.

67. spacer 2.7|25489|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031074 (Bacillus mycoides strain BPN401 plasmid pl41, complete sequence) position: , mismatch: 9, identity: 0.75

gcaagggatt----attataagaaaaataaatgtgatatt	CRISPR spacer
----gatacttccgattataagaaaaatatatctgatatt	Protospacer
    *. *.*    *************** ** *******

68. spacer 3.3|27276|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to MN694354 (Marine virus AFVG_250M116, complete genome) position: , mismatch: 9, identity: 0.735

atataatcttttttatggaggtgatacacttgat	CRISPR spacer
ttttaatcttttgtctggaggtgatactcaggtc	Protospacer
 * ********* * ************ *  * .

69. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015920 (Pediococcus pentosaceus strain wikim20 plasmid pKPP02, complete sequence) position: , mismatch: 9, identity: 0.735

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
ggcttctcattaattaatttttcaattttcttat	Protospacer
   *  *..******* * ***************

70. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029731 (Citrobacter sp. CRE-46 strain AR_0157 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.735

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
cgtcaattcttaattatgatttcaatttcataat	Protospacer
.  .**** ******** **********. * **

71. spacer 1.10|17425|36|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 10, identity: 0.722

tgaagcaagaagaaagaagcgaatttataaaagagt	CRISPR spacer
aaaaaatggaagaaagaagtaaatttataaaagaaa	Protospacer
 .**.  .***********..*************.

72. spacer 1.12|17557|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018283 (Chondrocystis sp. NIES-4102 plasmid plasmid2 DNA, complete genome) position: , mismatch: 10, identity: 0.714

tctattaaagattttaaagcaagattttcgcttat	CRISPR spacer
gaaattaaagtttttaaagcaatattttctatatc	Protospacer
   ******* *********** ******  *  .

73. spacer 1.16|17820|35|NC_015417|PILER-CR,CRISPRCasFinder,CRT matches to MT773556 (Myoviridae sp. isolate BML_4 genomic sequence) position: , mismatch: 10, identity: 0.714

acatctaatatagtaatagtcttttctttatcgtt	CRISPR spacer
tctgtaaatattgtaatagtcttttcttcatattc	Protospacer
 *  . ***** ****************.**  *.

74. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046399 (Bacillus sp. A260 plasmid unnamed11, complete sequence) position: , mismatch: 10, identity: 0.706

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
aattaattgttatttattaattcaattttgaata	Protospacer
   ********* ****** *********

75. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to AP013406 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S46-C34) position: , mismatch: 10, identity: 0.706

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
ggaatatttttaattattttttcaattttatatt	Protospacer
  .  *** ********* ********** *  *

76. spacer 3.8|27604|34|NC_015417|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019741 (Acinetobacter radioresistens DSM 6976 = NBRC 102413 = CIP 103788 strain NBRC 102413 plasmid pARA1, complete sequence) position: , mismatch: 10, identity: 0.706

tcgtaattgttaattattatttcaattttcttat	CRISPR spacer
atctgtttgttaatgattaattcaattttcaaaa	Protospacer
 . *. ******** **** **********  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1373 : 39222

Clostridium_botulinum_C_phage(50.0%)

transposase,integrase

attL 3385:3402|attR 41135:41152

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019278849.1\|1373_1511_+	hypothetical protein	Q332M5	Clostridium_botulinum_C_phage	1.9e-13	91.1
WP_013720765.1\|2263_2443_+	hypothetical protein	A0A2H4J069	uncultured_Caudovirales_phage	5.1e-14	80.8
WP_013720766.1\|2936_3140_+	hypothetical protein	NA	NA	NA	NA
3385:3402	attL	NA	NA	NA	NA
WP_013720767.1\|3795_4422_+\|transposase	IS607-like element ISCbo6 family transposase	Q331Z3	Clostridium_botulinum_C_phage	2.2e-56	57.8
WP_013720768.1\|4399_5533_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	2.2e-142	66.3
WP_013720769.1\|6515_7640_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3UZC2	Geobacillus_virus	8.0e-97	48.6
WP_013720771.1\|7864_8314_+	GIY-YIG nuclease family protein	X5JAC1	Clostridium_phage	4.7e-48	65.3
WP_013720772.1\|9072_10782_+	hypothetical protein	NA	NA	NA	NA
WP_013720774.1\|11877_12573_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.9e-28	36.4
WP_013720775.1\|12565_13000_+	sensor histidine kinase	NA	NA	NA	NA
WP_013720776.1\|13448_13598_-	hypothetical protein	NA	NA	NA	NA
WP_039244073.1\|13705_14836_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q332B3	Clostridium_botulinum_C_phage	6.2e-206	94.9
WP_013720778.1\|14969_15656_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_013720779.1\|15734_16076_+	hypothetical protein	NA	NA	NA	NA
WP_039244075.1\|18231_18456_-	alkaline phosphatase	NA	NA	NA	NA
WP_013720781.1\|18614_18917_+	hypothetical protein	Q331Y8	Clostridium_botulinum_C_phage	2.2e-41	80.0
WP_019279139.1\|19012_19765_+	hypothetical protein	NA	NA	NA	NA
WP_013720783.1\|19761_21618_+	hypothetical protein	NA	NA	NA	NA
WP_039244087.1\|21620_22553_+	hypothetical protein	NA	NA	NA	NA
WP_013720785.1\|22590_22749_-	ribbon-helix-helix domain-containing protein	NA	NA	NA	NA
WP_013720786.1\|22846_23980_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	3.6e-145	67.1
WP_013720787.1\|24146_24860_+	type I-B CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_013720788.1\|25788_27021_-\|transposase	IS256-like element ISCbo4 family transposase	A0A218MNI5	uncultured_virus	2.3e-52	52.1
WP_013720789.1\|27958_30445_+	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_039244034.1\|30547_31141_+\|transposase	IS607-like element ISCbo10 family transposase	A0A1V0SJI5	Klosneuvirus	2.5e-41	47.6
WP_013720791.1\|31177_32590_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	4.5e-89	42.1
WP_013720792.1\|33135_33807_+	type II toxin-antitoxin system PemK/MazF family toxin	Q332J9	Clostridium_botulinum_C_phage	5.4e-93	76.9
WP_013720793.1\|34256_35663_+	hypothetical protein	Q332J7	Clostridium_botulinum_C_phage	4.2e-220	79.5
WP_013720794.1\|35655_36750_+\|integrase	site-specific integrase	Q332J6	Clostridium_botulinum_C_phage	1.6e-142	70.4
WP_013720795.1\|36831_37215_+	hypothetical protein	Q332J5	Clostridium_botulinum_C_phage	9.8e-31	56.9
WP_013720796.1\|37272_39222_+	NAD-dependent DNA ligase LigA	Q332J4	Clostridium_botulinum_C_phage	0.0e+00	85.4
41135:41152	attR	NA	NA	NA	NA

DBSCAN-SWA_2

73362 : 91400

Clostridium_botulinum_C_phage(43.75%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013720837.1\|73362_73647_+	hypothetical protein	A0A068F2I2	Mycobacterium_phage	8.4e-11	39.7
WP_003368618.1\|73950_74136_+	hypothetical protein	Q332G2	Clostridium_botulinum_C_phage	5.2e-22	80.3
WP_013720838.1\|74220_75366_+	ATP-binding protein	NA	NA	NA	NA
WP_013720839.1\|75451_75616_+	hypothetical protein	NA	NA	NA	NA
WP_013720840.1\|75639_76377_-	hypothetical protein	Q332F7	Clostridium_botulinum_C_phage	7.8e-93	72.7
WP_013720841.1\|76919_77390_+	hypothetical protein	Q332F5	Clostridium_botulinum_C_phage	6.6e-21	60.0
WP_003368349.1\|77419_77560_+	hypothetical protein	NA	NA	NA	NA
WP_019279001.1\|77597_78341_+	hypothetical protein	Q332F4	Clostridium_botulinum_C_phage	2.1e-82	74.4
WP_019279002.1\|78365_78596_+	hypothetical protein	Q332F3	Clostridium_botulinum_C_phage	3.1e-32	93.4
WP_013720844.1\|78658_80779_+	anaerobic ribonucleoside-triphosphate reductase	K0NXZ0	Escherichia_virus	2.7e-154	43.3
WP_013720845.1\|80778_81288_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0K0QSK0	Citrobacter_phage	6.5e-30	42.7
WP_013720846.1\|81352_81820_+	dUTPase	Q332E8	Clostridium_botulinum_C_phage	3.7e-80	97.4
WP_141639619.1\|81812_81869_-	CRISPR-associated DxTHG motif protein	NA	NA	NA	NA
WP_013720847.1\|81848_82028_+	hypothetical protein	Q332E7	Clostridium_botulinum_C_phage	1.2e-20	76.3
WP_013720848.1\|82264_82795_+	hypothetical protein	A0A2I7R4P9	Vibrio_phage	3.8e-33	45.4
WP_013720849.1\|82941_83439_+	hypothetical protein	NA	NA	NA	NA
WP_013720850.1\|83682_84222_+	botulinum neurotoxin transcription-activating sigma factor BotR	Q9ZWV5	Clostridium_botulinum_D_phage	1.3e-89	94.4
WP_013720851.1\|84297_86169_-	botulinum neurotoxin hemagglutinin HA70 subunit	Q786X9	Clostridium_botulinum_D_phage	0.0e+00	92.9
WP_013720852.1\|86182_86623_-	hemagglutinin	Q786Y1	Clostridium_botulinum_D_phage	4.1e-73	97.3
WP_013720853.1\|86684_87581_-	ricin-type beta-trefoil lectin domain protein	Q38196	Clostridium_botulinum_phage	5.5e-141	93.0
WP_013720854.1\|87809_91400_+	non-toxic nonhemagglutinin NTNH	Q9ZX77	Clostridium_botulinum_D_phage	0.0e+00	95.7

DBSCAN-SWA_3

100541 : 112162

Clostridium_botulinum_C_phage(28.57%)

integrase

attL 96378:96394|attR 118670:118686

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
96378:96394	attL	NA	NA	NA	NA
WP_013720822.1\|100541_101237_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.2e-52	48.1
WP_013720864.1\|102930_103539_+	hypothetical protein	NA	NA	NA	NA
WP_013720865.1\|103708_107962_+	DNA topoisomerase	A0A0H3UZ54	Geobacillus_virus	0.0e+00	45.5
WP_013720867.1\|108074_108746_+	hypothetical protein	Q332C5	Clostridium_botulinum_C_phage	4.7e-113	87.4
WP_013720868.1\|108866_109265_+	hypothetical protein	G0YQG8	Erwinia_phage	9.6e-05	47.5
WP_013720869.1\|109334_109544_-	hypothetical protein	NA	NA	NA	NA
WP_013720870.1\|109550_109919_-	hypothetical protein	Q332C3	Clostridium_botulinum_C_phage	4.4e-52	87.7
WP_013720871.1\|109979_111008_-\|integrase	site-specific integrase	H7BV02	unidentified_phage	2.7e-75	45.3
WP_013720872.1\|111041_111260_-	hypothetical protein	NA	NA	NA	NA
WP_013720873.1\|111343_112162_-\|integrase	tyrosine-type recombinase/integrase	A0A0E3M2X0	Bacillus_phage	1.2e-12	23.8
118670:118686	attR	NA	NA	NA	NA

DBSCAN-SWA_4

115596 : 130224

Clostridium_botulinum_C_phage(88.24%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013720876.1\|115596_116553_-	hypothetical protein	Q332B7	Clostridium_botulinum_C_phage	2.5e-14	71.2
WP_013720878.1\|117026_117203_-	hypothetical protein	Q332B4	Clostridium_botulinum_C_phage	1.2e-20	72.4
WP_013720879.1\|117214_118711_-	DNRLRE domain-containing protein	Q332B2	Clostridium_botulinum_C_phage	1.5e-143	80.3
WP_013720880.1\|118703_119855_-	hypothetical protein	Q332B1	Clostridium_botulinum_C_phage	4.2e-194	88.5
WP_013720881.1\|119869_120487_-	hypothetical protein	Q332B0	Clostridium_botulinum_C_phage	1.8e-111	93.2
WP_013720882.1\|120531_121146_-	hypothetical protein	Q332A9	Clostridium_botulinum_C_phage	5.7e-97	94.5
WP_013720883.1\|121157_122525_-	hypothetical protein	Q332A8	Clostridium_botulinum_C_phage	1.9e-217	94.7
WP_013720884.1\|122551_122737_-	hypothetical protein	Q332A7	Clostridium_botulinum_C_phage	4.7e-23	93.0
WP_013720885.1\|122759_123122_-	hypothetical protein	Q332A6	Clostridium_botulinum_C_phage	7.8e-46	98.3
WP_013720886.1\|123180_123879_-	hypothetical protein	NA	NA	NA	NA
WP_013720887.1\|123900_124164_-	hypothetical protein	NA	NA	NA	NA
WP_019278944.1\|124433_125405_-	hypothetical protein	A0A0A0RSV1	Bacillus_phage	1.1e-06	41.0
WP_013720889.1\|125484_125817_-	membrane protein	S5MNN8	Brevibacillus_phage	3.8e-23	73.4
WP_013720891.1\|126297_126927_-	hypothetical protein	Q332A5	Clostridium_botulinum_C_phage	1.3e-104	99.0
WP_013720892.1\|126926_127226_-	hypothetical protein	Q332A4	Clostridium_botulinum_C_phage	2.7e-44	91.9
WP_013720893.1\|127455_127938_-	hypothetical protein	Q332A3	Clostridium_botulinum_C_phage	3.5e-78	96.2
WP_013720894.1\|127934_128456_-	ImmA/IrrE family metallo-endopeptidase	Q332A2	Clostridium_botulinum_C_phage	3.6e-92	99.4
WP_013720895.1\|128722_129271_-	hypothetical protein	NA	NA	NA	NA
WP_013720896.1\|129307_129463_-	hypothetical protein	NA	NA	NA	NA
WP_013720897.1\|129512_129815_-	hypothetical protein	Q331Y8	Clostridium_botulinum_C_phage	5.9e-39	79.0
WP_019279036.1\|130014_130224_+	helix-turn-helix transcriptional regulator	Q331Y7	Clostridium_botulinum_C_phage	4.1e-31	97.1

DBSCAN-SWA_5

142826 : 188279

Clostridium_botulinum_C_phage(66.67%)

tail,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013720912.1\|142826_143324_-	GNAT family N-acetyltransferase	A0A0M3ULL7	Bacillus_phage	1.6e-09	28.3
WP_013720913.1\|143326_143593_-	hypothetical protein	NA	NA	NA	NA
WP_003366606.1\|143780_144170_-	hypothetical protein	NA	NA	NA	NA
WP_013720914.1\|144147_144402_-	hypothetical protein	NA	NA	NA	NA
WP_013720915.1\|144578_144926_-	hypothetical protein	NA	NA	NA	NA
WP_013720916.1\|144936_145161_-	hypothetical protein	NA	NA	NA	NA
WP_013720917.1\|145729_150709_-	hypothetical protein	Q331Z6	Clostridium_botulinum_C_phage	0.0e+00	75.5
WP_013720918.1\|151079_152435_-\|tail	phage tail tape measure protein	Q331Z5	Clostridium_botulinum_C_phage	1.5e-182	66.7
WP_013720919.1\|152503_152971_-	hypothetical protein	Q331Z2	Clostridium_botulinum_C_phage	1.1e-44	87.4
WP_013720920.1\|152970_153531_-	hypothetical protein	Q331Z1	Clostridium_botulinum_C_phage	3.1e-73	79.6
WP_013720921.1\|153622_153925_-	hypothetical protein	Q331Y8	Clostridium_botulinum_C_phage	4.5e-39	77.0
WP_003366523.1\|154114_154309_+	helix-turn-helix transcriptional regulator	A0A139ZPH0	Marinitoga_camini_virus	1.1e-06	42.2
WP_013720922.1\|154458_154818_-	hypothetical protein	NA	NA	NA	NA
WP_013720923.1\|154831_155068_-	hypothetical protein	NA	NA	NA	NA
WP_013720924.1\|155291_155744_-	hypothetical protein	A0A0A7S1G5	Clostridium_phage	5.4e-20	39.1
WP_013720925.1\|155743_156412_-	SocA family protein	A0A0A7RUP2	Clostridium_phage	8.8e-51	46.0
WP_052306562.1\|156736_157273_-	type III toxin-antitoxin system ToxN/AbiQ family toxin	NA	NA	NA	NA
WP_013720927.1\|157761_158496_-	mono-ADP-ribosyltransferase C3	Q331X8	Clostridium_botulinum_C_phage	1.5e-91	66.8
WP_013720928.1\|159108_159564_-	hypothetical protein	Q331X7	Clostridium_botulinum_C_phage	6.2e-32	58.6
WP_013720929.1\|159740_160301_-	helix-turn-helix transcriptional regulator	Q331X6	Clostridium_botulinum_C_phage	2.7e-29	42.1
WP_013720930.1\|160323_160836_-	hypothetical protein	NA	NA	NA	NA
WP_003366439.1\|161309_161696_-	hypothetical protein	Q331X2	Clostridium_botulinum_C_phage	5.0e-59	93.0
WP_013720931.1\|161742_162657_-	N-acetylmuramoyl-L-alanine amidase	Q331X1	Clostridium_botulinum_C_phage	4.9e-153	90.9
WP_003366615.1\|162720_162960_-	hypothetical protein	NA	NA	NA	NA
WP_003366572.1\|162977_163769_-	hypothetical protein	A0A0K2FL50	Brevibacillus_phage	3.8e-29	31.7
WP_013720932.1\|163784_164525_-	hypothetical protein	NA	NA	NA	NA
WP_003366591.1\|164527_165055_-	hypothetical protein	Q331W7	Clostridium_botulinum_C_phage	8.1e-92	92.0
WP_003366411.1\|165070_165946_-	hypothetical protein	Q331W6	Clostridium_botulinum_C_phage	9.0e-64	49.5
WP_013720933.1\|165996_167202_-	hypothetical protein	Q331W5	Clostridium_botulinum_C_phage	3.0e-203	83.9
WP_003366611.1\|167216_167633_-	hypothetical protein	Q331W4	Clostridium_botulinum_C_phage	2.2e-68	93.5
WP_013720934.1\|167651_168179_-	hypothetical protein	Q331W3	Clostridium_botulinum_C_phage	4.9e-81	82.9
WP_013720935.1\|168261_169314_-	hypothetical protein	Q331W2	Clostridium_botulinum_C_phage	3.7e-189	96.6
WP_013720936.1\|169370_169916_-	hypothetical protein	Q331W1	Clostridium_botulinum_C_phage	6.2e-71	73.5
WP_013720937.1\|169961_171533_-	phage morphogeneis protein	Q331W0	Clostridium_botulinum_C_phage	1.1e-232	89.1
WP_013720938.1\|171569_171716_-	hypothetical protein	NA	NA	NA	NA
WP_013720939.1\|171743_173321_-	hypothetical protein	Q331V9	Clostridium_botulinum_C_phage	7.6e-287	93.9
WP_013720940.1\|173398_174217_-	hypothetical protein	A0A0K2FLD6	Brevibacillus_phage	9.8e-20	28.6
WP_013720941.1\|174576_175566_-	hypothetical protein	A0A218KCC8	Bacillus_phage	5.1e-23	25.8
WP_013720942.1\|175558_176491_-	hypothetical protein	NA	NA	NA	NA
WP_013720943.1\|176633_177356_-	phage regulatory protein/antirepressor Ant	Q331V6	Clostridium_botulinum_C_phage	5.3e-118	89.6
WP_013720944.1\|177357_177981_-	hypothetical protein	Q332K2	Clostridium_botulinum_C_phage	2.2e-16	37.9
WP_013720945.1\|178232_178946_-	hypothetical protein	NA	NA	NA	NA
WP_072060596.1\|179375_179930_-	phage antirepressor Ant	Q331V6	Clostridium_botulinum_C_phage	7.6e-24	41.5
WP_013720947.1\|180122_181301_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q331Z4	Clostridium_botulinum_C_phage	1.9e-218	97.7
WP_003367547.1\|181284_181896_-\|transposase	IS607 family transposase	Q331Z3	Clostridium_botulinum_C_phage	4.8e-104	98.0
WP_013720948.1\|182470_182737_-	hypothetical protein	A0A0A7RVU3	Clostridium_phage	3.4e-14	49.4
WP_013720949.1\|182970_183678_-	hypothetical protein	A0A1P8CWY0	Bacillus_phage	1.4e-22	33.0
WP_013720950.1\|184380_184605_-	hypothetical protein	NA	NA	NA	NA
WP_013720951.1\|184684_184972_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	1.2e-12	48.9
WP_013720952.1\|185254_185878_-	hypothetical protein	A0A1P8CWS4	Bacillus_phage	1.5e-41	48.5
WP_013720953.1\|186281_188279_-	hypothetical protein	A0A1P8CWS8	Bacillus_phage	7.1e-181	53.2

DBSCAN-SWA_6

192143 : 201616

Clostridium_botulinum_C_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013720958.1\|192143_192902_-	hypothetical protein	Q331U0	Clostridium_botulinum_C_phage	9.4e-118	85.7
WP_013720959.1\|193361_193547_-	hypothetical protein	NA	NA	NA	NA
WP_013720960.1\|193714_194446_-	MerR family transcriptional regulator	Q331T8	Clostridium_botulinum_C_phage	1.4e-62	64.5
WP_013720961.1\|194664_195735_-	cell division protein FtsZ	Q331T7	Clostridium_botulinum_C_phage	2.0e-177	88.0
WP_003367529.1\|195752_195998_-	hypothetical protein	Q331T6	Clostridium_botulinum_C_phage	5.8e-37	97.5
WP_003367566.1\|196495_196879_-	restriction endonuclease	Q331T5	Clostridium_botulinum_C_phage	1.0e-59	83.3
WP_003367553.1\|197287_197464_+	hypothetical protein	Q331T4	Clostridium_botulinum_C_phage	2.5e-21	86.2
WP_039244068.1\|197476_199363_+	cell division protein FtsK	Q331T3	Clostridium_botulinum_C_phage	1.6e-235	69.8
WP_013720964.1\|199366_199984_+	hypothetical protein	Q331T2	Clostridium_botulinum_C_phage	1.5e-97	83.4
WP_003367551.1\|200712_200955_+	hypothetical protein	Q331T1	Clostridium_botulinum_C_phage	6.6e-25	77.6
WP_003367525.1\|201095_201284_+	hypothetical protein	Q331T0	Clostridium_botulinum_C_phage	1.5e-21	91.9
WP_003367523.1\|201304_201616_+	hypothetical protein	Q331S9	Clostridium_botulinum_C_phage	1.1e-48	85.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_015426

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015426_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015426_1

74335-74691

Unclear

III-B

Consensus_repeat	Method
ATTTAAATACATCTCATGTTAATGTTCAAC	PILER-CR
ATTTAAATACATCTCATGTTAATGTTCAAC	CRT

5 spacers

cas3,cas6

The CRISPR arrays of NC_015426_1

>merge|NC_015426|1|74335-74691|PILER-CR,CRT
ATTTAAATACGTCTCATGTTAATGTTCAACTTTCAAACTTTTTGCCTATAGCATCTAGCTTTTGATTTAAATACATCTAATGTTAATGTTCAACTCATAAAGGTGAAATTTTAGACCTAATGGAAATGGCATTTAAATACATCTCATGTTAATGTTCAACTCCGCTTCCGTTTTCACCGAAAATATTTGTTATCGGATTTAAATACATCTCATGTTAATGTTCAACTAAAGCAAGAGTGGTTGAACTAATTAAACAAGGCTTATTTAAATACATCTCATGTTAATGTTCAACGGCAAAAAGATAACCGAGGTGGAAAATAAAGCTGAATTTAAATACATCTCATGTTAATGTTCAAC

>NC_015426|1|1|74335-74691|PILER-CR
ATTTAAATACGTCTCATGTTAATGTTCAAC	TTTCAAACTTTTTGCCTATAGCATCTAGCTTTTG
ATTTAAATACATCTAATGTTAATGTTCAAC	TCATAAAGGTGAAATTTTAGACCTAATGGAAATGGC
ATTTAAATACATCTCATGTTAATGTTCAAC	TCCGCTTCCGTTTTCACCGAAAATATTTGTTATCGG
ATTTAAATACATCTCATGTTAATGTTCAAC	TAAAGCAAGAGTGGTTGAACTAATTAAACAAGGCTT
ATTTAAATACATCTCATGTTAATGTTCAAC	GGCAAAAAGATAACCGAGGTGGAAAATAAAGCTGA
ATTTAAATACATCTCATGTTAATGTTCAAC

>NC_015426|1|1|74335-74691|CRT
ATTTAAATACGTCTCATGTTAATGTTCAAC	TTTCAAACTTTTTGCCTATAGCATCTAGCTTTTG
ATTTAAATACATCTAATGTTAATGTTCAAC	TCATAAAGGTGAAATTTTAGACCTAATGGAAATGGC
ATTTAAATACATCTCATGTTAATGTTCAAC	TCCGCTTCCGTTTTCACCGAAAATATTTGTTATCGG
ATTTAAATACATCTCATGTTAATGTTCAAC	TAAAGCAAGAGTGGTTGAACTAATTAAACAAGGCTT
ATTTAAATACATCTCATGTTAATGTTCAAC	GGCAAAAAGATAACCGAGGTGGAAAATAAAGCTGA
ATTTAAATACATCTCATGTTAATGTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015426.1\|WP_013726781.1\|69264_69909_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|223690
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09759_cas6_CAS-I-A	gnl\|CDD\|187889
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NC_015426.1\|WP_013726780.1\|68420_69260_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213231
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379719
NC_015426.1\|WP_013726796.1\|84885_85545_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|226071
NC_015426.1\|WP_013726799.1\|87286_89005_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726777.1\|64151_64979_-\|deoxyuridine-5'-triphosphate-nucleotidohydrolase	unknown	unknown	gnl\|CDD\|143638
NC_015426.1\|WP_019278497.1\|66462_68406_+\|ABC-transporter-permease	unknown	unknown	unknown
NC_015426.1\|WP_039258810.1\|73909_74197_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726795.1\|84312_84453_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726784.1\|72546_73014_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_015426.1\|WP_019278494.1\|75043_75409_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	unknown	unknown	gnl\|CDD\|273860
NC_015426.1\|WP_013726791.1\|79964_80429_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_167317602.1\|65096_66032_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726785.1\|73259_73640_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015426.1\|WP_013726777.1\|64151_64979_-\|deoxyuridine-5'-triphosphate-nucleotidohydrolase	gnl\|CDD\|143638	cd07557, trimeric_dUTPase, Trimeric dUTP diphosphatases. Trimeric dUTP diphosphatases, or dUTPases, are the most common family of dUTPase, found in bacteria, eukaryotes, and archaea. They catalyze the hydrolysis of the dUTP-Mg complex (dUTP-Mg) into dUMP and pyrophosphate. This reaction is crucial for the preservation of chromosomal integrity as it removes dUTP and therefore reduces the cellular dUTP/dTTP ratio, and prevents dUTP from being incorporated into DNA. It also provides dUMP as the precursor for dTTP synthesis via the thymidylate synthase pathway. dUTPases are homotrimeric, except some monomeric viral dUTPases, which have been shown to mimic a trimer. Active sites are located at the subunit interface.	3.29038e-16
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	gnl\|CDD\|223690	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis].	1.21561e-88
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.86929e-23
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.19116e-66
NC_015426.1\|WP_013726780.1\|68420_69260_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.76388e-92
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.66787e-122
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	gnl\|CDD\|226071	COG3541, COG3541, Predicted nucleotidyltransferase [General function prediction only].	6.0839e-33
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	5.50298e-08
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	gnl\|CDD\|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.54509e-06

>NC_015426.1|WP_039258810.1|73909_74197_+|hypothetical-protein
MFKISNDTFFKICKIVSISCILISIVGWIPTFCSILTPLWMLSVLVSPIGFIFSLITLIKYNWKLGILLALLNVIMFFSFFIVMHIGYTFFYPHN
>NC_015426.1|WP_013726785.1|73259_73640_-|hypothetical-protein
MSNSLKKSVKGNIKKVITGLIFISIIIFGIAFIKNYRTNEYIIIKTMSQAQEIAIRGEYEDYTMSKNMLKDLFKDYLLGDISKNTYEPQNKLNSILYKNEYMKAKELYLKYDKLQQKCTNSNKGKK
>NC_015426.1|WP_013726784.1|72546_73014_-|hypothetical-protein
MIKLYILVFVLKLVDCMFTTTKTKALIYGYDKFAAILKGVASITNAIILMNVVIAKSYTGIIVIGVAETLGTFLATGLFNKFKKDEEWTFFVAPRTREDSKIIADTLREQGIPTYTVEGYYNKNSVLSCIVTAKTKEESKIVYKVCKDKAKCKRI
>NC_015426.1|WP_013726783.1|71454_72474_-|nucleotidyltransferase
MNIDEIKQKLRSQEYDFLRTNEHLGNNIILLTTGGSYAYGTNIDTEEHTSDLDIRGICVERPEEIIGLSSFEQFENKETDTTIYGLRKVIKLLLNCNPNVIEILGTKDEHLFICTKAGKLLRDNLDLFISKKAIASFGGYSTAQLRRLQNALARDSYPQKEKEEHILKSIESQMLTMKDRYKEVKNEELKLYIDKSDKEDLESEIFIDISLKHYPLRDFKNIYSEMTQIVKDYDKLTHRNSKKDTLHLNKHAMHLIRLLLMGTEILEGKGVNTHREKDIELLLNIRNGKYSYNEIFEMVNDYDKQFKYAAEHTELQNNPDYKKVEELVMEINRGVINGQ
>NC_015426.1|WP_019278496.1|70130_71465_-|HD-domain-containing-protein
MDNNMEIKMPKCVGYIIHKLQEFNYEAYIVGGCVRDSLLKKTPNDWDITTSALPNKVVDIFQNLGYKIIPTGLKHGTVTIVINNEHYEVTTYRIDGEYEDNRHPKKVEFTRNLKEDLSRRDFTINSMAYNDKDGLVDYFNSKNDLESGIVKSVGDPMKRFSEDALRILRAYRFAAQLGFVIEDETLSATMQVKDNLKSISIERIRDEIDKMLLANSSIFFELSKFGVLEVILPELYQCFNVEQNNPYHVKNVFNHIINATLNIEPKLHLKLTMLLHDICKPQCKTTDEKGIDHFYNHAELSSNKSKEILKRMKYDNNTIDKVSTLVKYHDREIGSNKSIRKLLSLIGEDNFRDLLKVKEADIKAQNLKYYDERHNKLIEIEHKLNDIISKNQCFSLKDLKVNGRDLIELGYTGKEIGHILNDLLEKVLENPDLNNKDTLIGMIR
>NC_015426.1|WP_013726781.1|69264_69909_+|hypothetical-protein
MNLKLIYLSMKNLKIYYFIPLIFLYIVIPILDIGLINMSENIENSYQLIFAEAEKYIPILSLWWSTFIFKEYIDGDGNEVLYCIGSSSKLKIQHITLIFIWYIIHVSILFLGYSFFLDNVLLEFLKTIIQCFFFSSIAYMLIYTLKSTTISFMFLLIYELLCLFVRCEFIKYMSIFEGEQILSVQLISTKYAVFFLVGILFLLIGMYKNKRFYY
>NC_015426.1|WP_013726780.1|68420_69260_+|ATP-binding-cassette-domain-containing-protein
MLEILDLHKSFKRKEILKGISINLDTGIYGLLGKNGAGKTTLMRCIVNLYNTTKGNIKFEEKDIANDTSFSNNIGYLPQKFGLFKELTVYEMMEYFAVLKKLPKESMDMYIKSSLEIVNLEDRLKDKISTLSGGMIRRLGIAQAILGDPKIIIFDEPTAGLDPEERLRFKNLLSHIKKDKIIIISTHIVEDVEACCDKIIIMDDGKMLKEGSSDAIKSVAKGKVFEIPEETKINFNHFVEKTFEKDGKRFLRILSNENQEYTGLEPTIEDGYMCLLKGI
>NC_015426.1|WP_019278497.1|66462_68406_+|ABC-transporter-permease
MTNLIKSNFKIFFRSLYLSVPLLIFFIILNGYLGVGIRNLTIHKDALFYLQYSQRISVIYFIFFTFISYEYLIKSKNSNLLESISVLNKGTLKLYFSKLIVLVAIILIMTLNIFAYNFIVYIVMKVHSTSYLLHIILNHLLNIFLVSIFAVCIGSTISLYFKRFPAYALMILSVILISPISEKVPYILHMGYNIDIYFLREPFNILPPNLNWESEYLYGLSIEPYRWNLIAFWISFLSFLMILKLSKRKYKSLNITAAILLIFSLGNFYGFTKPGSILKKDYNPKNFTAFDEIYYSDDVQKEEKALFKISEYDMKLNINRELENDIIIHLNEKEPLKTYKFTLYRNYKIKKVLGKNNETLEYKRDGDYLEVINPTNNKLNEIRIVYSGSSPVFYSNCQGVLLPGYFPYYPTEGYKRMYTDGGRFVPVIRDYTVKFNISLKSNLDIASNLDKKDSKLSGQAQEVTLMGGFLKEKSVKDNIVYELLLDKMDTSVFSHIDNNINSYNKILSSNYKFTIKSKKIFQAPTTLLNRVAYNGIADFKDHIIVPGLDANVLSLDLIQSNLLKNIKKKQISDMLFEYILDKDSFTDKKRFEEMPKEMFEDPFYQIDYLFLEKINKLGGDYVIKNSYKFLIDENDKRDAMTFVKNLK
>NC_015426.1|WP_167317602.1|65096_66032_-|hypothetical-protein
MEKEISYICNCEYEYFLNKANVVGIGCGYKVQNGFYTKKLCIQVFVSRKLPSNELNSQDIVPNLYKEIPTDVKETGYFKPCSLIQKVRPILGGYVIGNEYNTAHSGTLGCLVKDSKDLFILSNNHVLTMINQAPLGTKIIQPSCQYKGDIKTDVIGNLSKYIKIKFKGAITTPTNYTDCSIAKVIDKSLVSPKIALVGMPKGINTPKLNENVKKVGAISELTTGVITSLHTTIRVNYDILKKAAIYKEQILTTQMAEGGDSGAVLLDKNNYVVALLMSGSKNTSTFNPINTVLKQLKVSIVTSDSWNEIDK
>NC_015426.1|WP_013726777.1|64151_64979_-|deoxyuridine-5'-triphosphate-nucleotidohydrolase
MEVMKKLLFLKDVEIFNKVFKKGESLDIVDKNAIMDKVKGIIVYKIEEHMNLDGVLESTQCEHFINNTMLNSLLDNKLATIDEVEFNELYFAKTKPNAIIPTKREEDAGYDVYTCETETIVIEPCSLRMIDTGIAIACNKAYFPKFFDKGGMGSKGIIVGAGVGDSGYRDSYFIPLINTNLQKTVVITTQSDEEIEKCTHFDLEQNKFITIDSNADVRVCEYVKKEDCIIKPINKAITQFVMLPVPTFNTKEVSWEQLKNIKSERGLGKLGSSGK
>NC_015426.1|WP_019278494.1|75043_75409_-|hypothetical-protein
MRKVTNILTSLSLFIFSILILIDFMIIGSDIPVNIHRNEVIFFIILNVIYILLQTAYINTVKTIPRKINIYLITFVSFIWLMLLIDELTYSYHIYCRISEIIGLTSQIYILIKYIKKVYII
>NC_015426.1|WP_013726790.1|77873_79892_-|CRISPR-associated-helicase/endonuclease-Cas3
MNDLNDKLKQYKAKSDGTTLFQHNQDLLVALEQLSKIHSIPQELKNSLIKCIKYHDIGKVTDDFQNNIESKHRNIRHEIISASAKDLDDNERLNILLHHRVLEKLAQFINNVYYKDSLNEVKNKLNIKVEDITSYLKKICRGGRENHKKLHNKDLIIQLGLLKMCDHIASAGINNIDIGLNTKEVFNFEKYRSIQEKVLNLKEVKDIIIQAPTGLGKTETALLWTNLVQNKFKGKRIFYILPYTASINALYKRFKEQNISVGVLHSKVQSLLSRDEDIENIEEELQLFKKNIKQVTICTIFQLLKAMFSCKNFEMILAQLKDSIIVIDEIHCFDLRTFAFMMESLKYLRENFGINICIMSASIPTCMLEFMKETLNINTLINADKEDFLIRHHINRVDKELVNDLDKIKAAIENNKQALLCVNNVAASQKLFSNLKEQYPNKNIKLIHGRFNARDRSEIEKDLKNCDVLIGTQAIEVSLDIDYDVLYTEMAPLDALLQRFGRVNRKGEKGIADVYIYNKSKEYNSIYDNNIIDKTDIELNNIIKNDSGIILEDKVNLYLDNIYTEFNIDEYNQYKKQINDIINNIRVGYYNENACEEMLSNDNSVQMIPVSLLSEYIKSREEKRYIEGNELFVNSKKYLSEYNKNLRIYITDRVYDIRGLVEKEIDIDNQMV
>NC_015426.1|WP_013726791.1|79964_80429_-|hypothetical-protein
MNYENSEQIEQIPVLIQKLYSIVNELETSFKGRKFTLDGHLVGSIGEVLVSYYYDLELLPNSTKTHDAKTKDNKLVQIKATQGKSIGISSKPNYLIVIKILPDGSIEEIYNGSGNLAWSNVGKVQKNGQCNISVNKLKNLMSEVPETSRIPKIR
>NC_015426.1|WP_013720788.1|81199_82432_-|IS256-like-element-ISCbo4-family-transposase
MRNFEVPDFDYKEEVKKCKSLDDVMGKNGLIQRMLKDVIQNILEAEMEDHLGRDKYERNSENNSKNYRNGYSKKNIRSSFGDIDVDIPRDRNAEFEPKVIKKYETVCNELDKKVIGLYARGMSTRDIQAEIEDLYGITISPSMVSKITDKVIGAATAWQNRTLDRIYPIVYMDAMHFKVRDDNRIVSKAAYICMAYDMSGHKDILGIWVGESEGAKFWLSVCNDLKNRGVKQILIACMDGLRGLPDAIKTVYPEVSIQTCIVHQIRNSLKYIASKDKKEFIKDLKLIYKATTEELALLELDNLKEKWGSKYGIVIDSWYNNWDNLSTFFEFSPEIRKMIYTTNALEGFNRQIRKFTKTRTVFPTDESLKKSLYLATMEIMEKWTSPRQNWALTLGQLTITFGNKIDEFLA
>NC_015426.1|WP_013726795.1|84312_84453_-|hypothetical-protein
MLNKNKKENKEKQDLFDLYQYDMLVDFKEFKSTKNRMTIGFMNLDK
>NC_015426.1|WP_013726796.1|84885_85545_-|hypothetical-protein
MERTYNVFIDNGLYVLANEIDKEIQDITLKDIKNSTNIFAKRFEEYASCEYYKKNVSMGFQNSAYTQALKKDKETKQENETRSEKVQNQYNLILSNMGNDEYCSICGKKHVNLNPNINYVKSFTRCWMPHIHANTFINYINNLEMVNICPVCLYLSMISIFNFEKAGDKIILYSSDDNDFMKDYTYDKQIEVKNNIAMCAKESKEKTNNIKSITEVIKK
>NC_015426.1|WP_013726797.1|85546_86302_-|CRISPR-associated-endoribonuclease-Cas6
MLSRKSIILQAQNDGVLDYNWNYPLSINLFNKMSLYDAKFAEFLHDEGFKSKDEKKKKFKLINFMLLFNNQKMDSEGININKNDESVLIISGYKDPMNAILQGLCINNEINLNNVIFKVIDVKEDKKVKFNKINIYKAMTPIVESIWEDNSVKFLNPYQSKYYDAIKQNLNRKYEIIYNKPYSGELKLMIENMLKIKQKSIRIKNGYIQGYSNFEILVQCNKNMQKVAYYCGLGQNSSMGAGLVNYITGGE
>NC_015426.1|WP_019278491.1|86280_86925_-|CRISPR-associated-protein-Cas5
MEFKKLVLTSKMAHFKNGINGKNQNTFRVPPISTIVGILKNIYGKDIKDFIFGYTCKYDGIFKDVTTIYKEVNLDISSAKGDRFQHDIAFIEYLVNPIITVYTNLDTPIKINDILNLGKTNCLAKCKFEKENITNKECIGYNQWTPINTGNGKIKRINKETIYNQNKGYYDYYTELFRLNEEFTAKHILEDQEEGIQLWQYRGVGDIECYQENL
>NC_015426.1|WP_013726799.1|87286_89005_-|hypothetical-protein
MENNEKINSKKKIINENTTVIDNNIIESPLFISSLKEVVEVEQLEKYIDKNRSIHRVIEVIKEDYEGTSNPKNYKNVPVVYRQWTDSKGLERQLLVTHAIPDMYTMDVWNALIGLYIQKISPIHFNNNKNTYDLDVNEMEFTLYELAKFMNKSTGGSTLDKLMKEIVRLNNAKYYSFANGVIFDKKKEKYLKSKTKGMSLILDCEFDSEKRVKDEKVNSKCKVEFNKLIIDNIRYQYIKYIDPKEYFALPSRGLTRRLYVYLKGNSHQSNGTKYTYIKRNFYVLKNNIPILEKQPSKIKERLKVPLKNLIKNGMITDYFYGDEDVINEQEPCIYFIFKGQKDEVINSLRKKYEEKQLQLEVAADNIKKDEFQMKIPENLDKTLEEIGFNAKVIKQLYAEYDKWEIIKYVIWLQQQQFKSKCTIQNPAGLLRFALMGNINLDLTNKDIVEFVENEQKKFIENKLSREEIVQNAYDKYVNEEMEKFKTEDNATHDIIYENTLINIEAQVDLQIAQLRLLEKNEGVEMPSLKLWEEFREKKDKSELFKKNFINSAKVLRGIMTLEEFKVEFGNDK
>NC_015426.1|WP_013726800.1|89440_90865_+|WG-repeat-containing-protein
MKKILKVFLVCMFMMFLTSCSNEKEISLPKDVNRISNVCYLGKNIYGIDIAPIPKGTFPKRNYKLINLKGNIISKEDIIYIDKECSFLDNGAVSVLNKDKKSMLISKDGKVIDDRYTIYSYLGNGVFAVSKNFKTGYCNSKGEDIVPPIDFMSICNVQKGDKFPYKNNEGKLGFIDTKGKTVIPFVFDGIGKYSKDANFISASKDKKWGLINKDGKTIIPFKFSWLFPCEDGNFIVELNNKCGLIDKNSKVIIPFEFDLILEIKKGTYKVLLIDKFNCNKLYGVMDNRGKTIVKPFEAFKIDYADNKNIVSNAVDDMGNSLEYTKMMHQLLDTNRKELTPDFYEEITYYKDDLFRVKNNNKYGFINRSGKVVIPVKFNNFLEFNDNFCIVDLNGKYGILDKSGHYKINPKYEDIKYLCKNSFAVKLNNKWGIVDSCDKLIKPIEYDDISSIESHIECKYNVLMKKGQKGILLKI

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Crispr_ID: NC_015426_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015426_2

75803-77677

Unclear

Consensus_repeat	Method
ATTTATAACTAACATAGTTCTATTAATAC	PILER-CR
ATTTATAACTAACATAGTTCTATTAATAC	CRISPRCasFinder
ATTTATAACTAACATAGTTCTATTAATAC	CRT

28 spacers

cas3,cas6

The CRISPR arrays of NC_015426_2

>merge|NC_015426|2|75803-77677|PILER-CR,CRISPRCasFinder,CRT
ATTTATAACTAAGATAGTTCTATTAATACTTCTTTAATTGATAAATGTAACAATTTCATTTCTGGATTTATAACTAACATAGTTCTATTAATACTCAGCTTGATACAGAGCCTCTAAGTTATTTCAATAGTCATTTATAACTAACATAGTTCTATTAATACTGAGGGCTTTTTTGATCTTTAAAACAGTTTCTATACCATTTATAACTAACATAGTTCTATTAATACTTTGAAGCTTATCACCTATAAGTTTGTATTTTTTTCATTTATAACTAACATAGTTCTATTAATACATGCAGTTTTAAAGTCTTTATTATTAGCTAGTGTTGCATTTATAACTAACATAGTTCTATTAATACCCGCATTGAATAATTTTTTAGTTAAACATTTAAATTTAATTTATAACTAACATAGTTCTATTAATACGGATTATAGTAGTAGATAGAAAATTAGATTTAAAAAGAATTTATAACTAACATAGTTCTATTAATACGCAATGGGTATGCGACTAGGTGGAGCTGGACATCAAGTATTTATAACTAACATAGTTCTATTAATACATAGTTTAAAAATGTTGTTCTTCCTCTGTTAAATAATTTATAACTAACATAGTTCTATTAATACGTGATTTAGCTGCTACAAATCCAAATGCTATTTCAACATTTATAACTAACATAGTTCTATTAATACTTCAAGGAAGTGGTATTGGTCTGAATACTCTATCTTTATTTATAACTAACATAGTTCTATTAATACCAGATTACTTGGAACAAATAAAGTCAATAGTCTCTGGATTTATAACTAACATAGTTCTATTAATACTAATTTCTTTTGCTTCATCTTTTTTACTTTCGTAGGCATTTATAACTAACATAGTTCTATTAATACCTATATATTTTTGACTACCTTCCGATTTAGTTCCATAATTTATAACTAACATAGTTCTATTAATACACAAAAAAATAACACATCCGTATCAATCGATTAGTTATTTATAACTAACATAGTTCTATTAATACGCAAGATGATAGCTGGTATGGCTAAAGATTATTTCAATTTATAACTAACATAGTTCTATTAATACGTGCAAGACGTGTCATGTTATAAGTCTTTCCTTGACCATTTATAACTAACATAGTTCTATTAATACCAATACTGAACTATCCTAAGAGTGATATTCGCTCAATTGGATTTATAACTAACATAGTTCTATTAATACAGATTATAATAGAGTGACACAAAATTAAAACAATGTATTTATAACTAACATAGTTCTATTAATACGTTAAAAGATTGCTTAATTTTAGAAGATTGCTGAAAATTTATAACTAACATAGTTCTATTAATACCAAGCAACCATGAGTTTGATTGAGCATGGTAATTTAAGATTTATAACTAACATAGTTCTATTAATACCAACATATATTCACCACTTACAAGTTTTCTCATATAATTTATAACTAACATAGTTCTATTAATACGGTTTTATTTTGAAGATGAATTTAATACTCTTTTTAAATTTATAACTAACATAGTTCTATTAATACATTCAGACGTGAGTATAAATTAGCAGCTGCCAACAATTTATAACTAACATAGTTCTATTAATACAGATGAAAGAGTTTATTTATCTAAGCAATATGGAAAATTTATAACTAACATAGTTCTATTAATACCAAGCACGTTAGTATATGCATAGATGGAAAATCTGAAGATTTATAACTAACATAGTTCTATTAATACGGAAAAAAATAAAAATATATAAACTTCAAGTACCTAAATTTATAACTAACATAGTTCTATTAATACATAGAAGGAATAAGCATTTTAGAAAATGCAGTTAAATTATTTATAACTAACATAGTTCTATTAATAC

>NC_015426|2|2|75803-77677|PILER-CR
ATTTATAACTAAGATAGTTCTATTAATAC	TTCTTTAATTGATAAATGTAACAATTTCATTTCTGG
ATTTATAACTAACATAGTTCTATTAATAC	TCAGCTTGATACAGAGCCTCTAAGTTATTTCAATAGTC
ATTTATAACTAACATAGTTCTATTAATAC	TGAGGGCTTTTTTGATCTTTAAAACAGTTTCTATACC
ATTTATAACTAACATAGTTCTATTAATAC	TTTGAAGCTTATCACCTATAAGTTTGTATTTTTTTC
ATTTATAACTAACATAGTTCTATTAATAC	ATGCAGTTTTAAAGTCTTTATTATTAGCTAGTGTTGC
ATTTATAACTAACATAGTTCTATTAATAC	CCGCATTGAATAATTTTTTAGTTAAACATTTAAATTTA
ATTTATAACTAACATAGTTCTATTAATAC	GGATTATAGTAGTAGATAGAAAATTAGATTTAAAAAGA
ATTTATAACTAACATAGTTCTATTAATAC	GCAATGGGTATGCGACTAGGTGGAGCTGGACATCAAGT
ATTTATAACTAACATAGTTCTATTAATAC	ATAGTTTAAAAATGTTGTTCTTCCTCTGTTAAATA
ATTTATAACTAACATAGTTCTATTAATAC	GTGATTTAGCTGCTACAAATCCAAATGCTATTTCAAC
ATTTATAACTAACATAGTTCTATTAATAC	TTCAAGGAAGTGGTATTGGTCTGAATACTCTATCTTT
ATTTATAACTAACATAGTTCTATTAATAC	CAGATTACTTGGAACAAATAAAGTCAATAGTCTCTGG
ATTTATAACTAACATAGTTCTATTAATAC	TAATTTCTTTTGCTTCATCTTTTTTACTTTCGTAGGC
ATTTATAACTAACATAGTTCTATTAATAC	CTATATATTTTTGACTACCTTCCGATTTAGTTCCATA
ATTTATAACTAACATAGTTCTATTAATAC	ACAAAAAAATAACACATCCGTATCAATCGATTAGTT
ATTTATAACTAACATAGTTCTATTAATAC	GCAAGATGATAGCTGGTATGGCTAAAGATTATTTCA
ATTTATAACTAACATAGTTCTATTAATAC	GTGCAAGACGTGTCATGTTATAAGTCTTTCCTTGACC
ATTTATAACTAACATAGTTCTATTAATAC	CAATACTGAACTATCCTAAGAGTGATATTCGCTCAATTGG
ATTTATAACTAACATAGTTCTATTAATAC	AGATTATAATAGAGTGACACAAAATTAAAACAATGT
ATTTATAACTAACATAGTTCTATTAATAC	GTTAAAAGATTGCTTAATTTTAGAAGATTGCTGAAA
ATTTATAACTAACATAGTTCTATTAATAC	CAAGCAACCATGAGTTTGATTGAGCATGGTAATTTAAG
ATTTATAACTAACATAGTTCTATTAATAC	CAACATATATTCACCACTTACAAGTTTTCTCATATA
ATTTATAACTAACATAGTTCTATTAATAC	GGTTTTATTTTGAAGATGAATTTAATACTCTTTTTAA
ATTTATAACTAACATAGTTCTATTAATAC	ATTCAGACGTGAGTATAAATTAGCAGCTGCCAACA
ATTTATAACTAACATAGTTCTATTAATAC	AGATGAAAGAGTTTATTTATCTAAGCAATATGGAAA
ATTTATAACTAACATAGTTCTATTAATAC	CAAGCACGTTAGTATATGCATAGATGGAAAATCTGAAG
ATTTATAACTAACATAGTTCTATTAATAC	GGAAAAAAATAAAAATATATAAACTTCAAGTACCTAA
ATTTATAACTAACATAGTTCTATTAATAC	ATAGAAGGAATAAGCATTTTAGAAAATGCAGTTAAATT
ATTTATAACTAACATAGTTCTATTAATAC

>NC_015426|2|1|75803-77677|CRISPRCasFinder
ATTTATAACTAAGATAGTTCTATTAATAC	TTCTTTAATTGATAAATGTAACAATTTCATTTCTGG
ATTTATAACTAACATAGTTCTATTAATAC	TCAGCTTGATACAGAGCCTCTAAGTTATTTCAATAGTC
ATTTATAACTAACATAGTTCTATTAATAC	TGAGGGCTTTTTTGATCTTTAAAACAGTTTCTATACC
ATTTATAACTAACATAGTTCTATTAATAC	TTTGAAGCTTATCACCTATAAGTTTGTATTTTTTTC
ATTTATAACTAACATAGTTCTATTAATAC	ATGCAGTTTTAAAGTCTTTATTATTAGCTAGTGTTGC
ATTTATAACTAACATAGTTCTATTAATAC	CCGCATTGAATAATTTTTTAGTTAAACATTTAAATTTA
ATTTATAACTAACATAGTTCTATTAATAC	GGATTATAGTAGTAGATAGAAAATTAGATTTAAAAAGA
ATTTATAACTAACATAGTTCTATTAATAC	GCAATGGGTATGCGACTAGGTGGAGCTGGACATCAAGT
ATTTATAACTAACATAGTTCTATTAATAC	ATAGTTTAAAAATGTTGTTCTTCCTCTGTTAAATA
ATTTATAACTAACATAGTTCTATTAATAC	GTGATTTAGCTGCTACAAATCCAAATGCTATTTCAAC
ATTTATAACTAACATAGTTCTATTAATAC	TTCAAGGAAGTGGTATTGGTCTGAATACTCTATCTTT
ATTTATAACTAACATAGTTCTATTAATAC	CAGATTACTTGGAACAAATAAAGTCAATAGTCTCTGG
ATTTATAACTAACATAGTTCTATTAATAC	TAATTTCTTTTGCTTCATCTTTTTTACTTTCGTAGGC
ATTTATAACTAACATAGTTCTATTAATAC	CTATATATTTTTGACTACCTTCCGATTTAGTTCCATA
ATTTATAACTAACATAGTTCTATTAATAC	ACAAAAAAATAACACATCCGTATCAATCGATTAGTT
ATTTATAACTAACATAGTTCTATTAATAC	GCAAGATGATAGCTGGTATGGCTAAAGATTATTTCA
ATTTATAACTAACATAGTTCTATTAATAC	GTGCAAGACGTGTCATGTTATAAGTCTTTCCTTGACC
ATTTATAACTAACATAGTTCTATTAATAC	CAATACTGAACTATCCTAAGAGTGATATTCGCTCAATTGG
ATTTATAACTAACATAGTTCTATTAATAC	AGATTATAATAGAGTGACACAAAATTAAAACAATGT
ATTTATAACTAACATAGTTCTATTAATAC	GTTAAAAGATTGCTTAATTTTAGAAGATTGCTGAAA
ATTTATAACTAACATAGTTCTATTAATAC	CAAGCAACCATGAGTTTGATTGAGCATGGTAATTTAAG
ATTTATAACTAACATAGTTCTATTAATAC	CAACATATATTCACCACTTACAAGTTTTCTCATATA
ATTTATAACTAACATAGTTCTATTAATAC	GGTTTTATTTTGAAGATGAATTTAATACTCTTTTTAA
ATTTATAACTAACATAGTTCTATTAATAC	ATTCAGACGTGAGTATAAATTAGCAGCTGCCAACA
ATTTATAACTAACATAGTTCTATTAATAC	AGATGAAAGAGTTTATTTATCTAAGCAATATGGAAA
ATTTATAACTAACATAGTTCTATTAATAC	CAAGCACGTTAGTATATGCATAGATGGAAAATCTGAAG
ATTTATAACTAACATAGTTCTATTAATAC	GGAAAAAAATAAAAATATATAAACTTCAAGTACCTAA
ATTTATAACTAACATAGTTCTATTAATAC	ATAGAAGGAATAAGCATTTTAGAAAATGCAGTTAAATT
ATTTATAACTAACATAGTTCTATTAATAC

>NC_015426|2|2|75803-77677|CRT
ATTTATAACTAAGATAGTTCTATTAATAC	TTCTTTAATTGATAAATGTAACAATTTCATTTCTGG
ATTTATAACTAACATAGTTCTATTAATAC	TCAGCTTGATACAGAGCCTCTAAGTTATTTCAATAGTC
ATTTATAACTAACATAGTTCTATTAATAC	TGAGGGCTTTTTTGATCTTTAAAACAGTTTCTATACC
ATTTATAACTAACATAGTTCTATTAATAC	TTTGAAGCTTATCACCTATAAGTTTGTATTTTTTTC
ATTTATAACTAACATAGTTCTATTAATAC	ATGCAGTTTTAAAGTCTTTATTATTAGCTAGTGTTGC
ATTTATAACTAACATAGTTCTATTAATAC	CCGCATTGAATAATTTTTTAGTTAAACATTTAAATTTA
ATTTATAACTAACATAGTTCTATTAATAC	GGATTATAGTAGTAGATAGAAAATTAGATTTAAAAAGA
ATTTATAACTAACATAGTTCTATTAATAC	GCAATGGGTATGCGACTAGGTGGAGCTGGACATCAAGT
ATTTATAACTAACATAGTTCTATTAATAC	ATAGTTTAAAAATGTTGTTCTTCCTCTGTTAAATA
ATTTATAACTAACATAGTTCTATTAATAC	GTGATTTAGCTGCTACAAATCCAAATGCTATTTCAAC
ATTTATAACTAACATAGTTCTATTAATAC	TTCAAGGAAGTGGTATTGGTCTGAATACTCTATCTTT
ATTTATAACTAACATAGTTCTATTAATAC	CAGATTACTTGGAACAAATAAAGTCAATAGTCTCTGG
ATTTATAACTAACATAGTTCTATTAATAC	TAATTTCTTTTGCTTCATCTTTTTTACTTTCGTAGGC
ATTTATAACTAACATAGTTCTATTAATAC	CTATATATTTTTGACTACCTTCCGATTTAGTTCCATA
ATTTATAACTAACATAGTTCTATTAATAC	ACAAAAAAATAACACATCCGTATCAATCGATTAGTT
ATTTATAACTAACATAGTTCTATTAATAC	GCAAGATGATAGCTGGTATGGCTAAAGATTATTTCA
ATTTATAACTAACATAGTTCTATTAATAC	GTGCAAGACGTGTCATGTTATAAGTCTTTCCTTGACC
ATTTATAACTAACATAGTTCTATTAATAC	CAATACTGAACTATCCTAAGAGTGATATTCGCTCAATTGG
ATTTATAACTAACATAGTTCTATTAATAC	AGATTATAATAGAGTGACACAAAATTAAAACAATGT
ATTTATAACTAACATAGTTCTATTAATAC	GTTAAAAGATTGCTTAATTTTAGAAGATTGCTGAAA
ATTTATAACTAACATAGTTCTATTAATAC	CAAGCAACCATGAGTTTGATTGAGCATGGTAATTTAAG
ATTTATAACTAACATAGTTCTATTAATAC	CAACATATATTCACCACTTACAAGTTTTCTCATATA
ATTTATAACTAACATAGTTCTATTAATAC	GGTTTTATTTTGAAGATGAATTTAATACTCTTTTTAA
ATTTATAACTAACATAGTTCTATTAATAC	ATTCAGACGTGAGTATAAATTAGCAGCTGCCAACA
ATTTATAACTAACATAGTTCTATTAATAC	AGATGAAAGAGTTTATTTATCTAAGCAATATGGAAA
ATTTATAACTAACATAGTTCTATTAATAC	CAAGCACGTTAGTATATGCATAGATGGAAAATCTGAAG
ATTTATAACTAACATAGTTCTATTAATAC	GGAAAAAAATAAAAATATATAAACTTCAAGTACCTAA
ATTTATAACTAACATAGTTCTATTAATAC	ATAGAAGGAATAAGCATTTTAGAAAATGCAGTTAAATT
ATTTATAACTAACATAGTTCTATTAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015426.1\|WP_013726781.1\|69264_69909_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|223690
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09759_cas6_CAS-I-A	gnl\|CDD\|187889
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NC_015426.1\|WP_013726780.1\|68420_69260_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213231
NC_015426.1\|WP_013726796.1\|84885_85545_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|226071
NC_015426.1\|WP_013726799.1\|87286_89005_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	unknown	unknown	gnl\|CDD\|273860
NC_015426.1\|WP_019278497.1\|66462_68406_+\|ABC-transporter-permease	unknown	unknown	unknown
NC_015426.1\|WP_039258810.1\|73909_74197_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726795.1\|84312_84453_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726784.1\|72546_73014_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278492.1\|90965_93032_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_015426.1\|WP_019278494.1\|75043_75409_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379719
NC_015426.1\|WP_013726791.1\|79964_80429_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_167317602.1\|65096_66032_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726785.1\|73259_73640_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	gnl\|CDD\|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.54509e-06
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	5.50298e-08
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	gnl\|CDD\|226071	COG3541, COG3541, Predicted nucleotidyltransferase [General function prediction only].	6.0839e-33
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	gnl\|CDD\|223690	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis].	1.21561e-88
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.19116e-66
NC_015426.1\|WP_013726780.1\|68420_69260_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.76388e-92
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.66787e-122
NC_015426.1\|WP_019278492.1\|90965_93032_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.52903e-40
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.86929e-23

>NC_015426.1|WP_019278494.1|75043_75409_-|hypothetical-protein
MRKVTNILTSLSLFIFSILILIDFMIIGSDIPVNIHRNEVIFFIILNVIYILLQTAYINTVKTIPRKINIYLITFVSFIWLMLLIDELTYSYHIYCRISEIIGLTSQIYILIKYIKKVYII
>NC_015426.1|WP_039258810.1|73909_74197_+|hypothetical-protein
MFKISNDTFFKICKIVSISCILISIVGWIPTFCSILTPLWMLSVLVSPIGFIFSLITLIKYNWKLGILLALLNVIMFFSFFIVMHIGYTFFYPHN
>NC_015426.1|WP_013726785.1|73259_73640_-|hypothetical-protein
MSNSLKKSVKGNIKKVITGLIFISIIIFGIAFIKNYRTNEYIIIKTMSQAQEIAIRGEYEDYTMSKNMLKDLFKDYLLGDISKNTYEPQNKLNSILYKNEYMKAKELYLKYDKLQQKCTNSNKGKK
>NC_015426.1|WP_013726784.1|72546_73014_-|hypothetical-protein
MIKLYILVFVLKLVDCMFTTTKTKALIYGYDKFAAILKGVASITNAIILMNVVIAKSYTGIIVIGVAETLGTFLATGLFNKFKKDEEWTFFVAPRTREDSKIIADTLREQGIPTYTVEGYYNKNSVLSCIVTAKTKEESKIVYKVCKDKAKCKRI
>NC_015426.1|WP_013726783.1|71454_72474_-|nucleotidyltransferase
MNIDEIKQKLRSQEYDFLRTNEHLGNNIILLTTGGSYAYGTNIDTEEHTSDLDIRGICVERPEEIIGLSSFEQFENKETDTTIYGLRKVIKLLLNCNPNVIEILGTKDEHLFICTKAGKLLRDNLDLFISKKAIASFGGYSTAQLRRLQNALARDSYPQKEKEEHILKSIESQMLTMKDRYKEVKNEELKLYIDKSDKEDLESEIFIDISLKHYPLRDFKNIYSEMTQIVKDYDKLTHRNSKKDTLHLNKHAMHLIRLLLMGTEILEGKGVNTHREKDIELLLNIRNGKYSYNEIFEMVNDYDKQFKYAAEHTELQNNPDYKKVEELVMEINRGVINGQ
>NC_015426.1|WP_019278496.1|70130_71465_-|HD-domain-containing-protein
MDNNMEIKMPKCVGYIIHKLQEFNYEAYIVGGCVRDSLLKKTPNDWDITTSALPNKVVDIFQNLGYKIIPTGLKHGTVTIVINNEHYEVTTYRIDGEYEDNRHPKKVEFTRNLKEDLSRRDFTINSMAYNDKDGLVDYFNSKNDLESGIVKSVGDPMKRFSEDALRILRAYRFAAQLGFVIEDETLSATMQVKDNLKSISIERIRDEIDKMLLANSSIFFELSKFGVLEVILPELYQCFNVEQNNPYHVKNVFNHIINATLNIEPKLHLKLTMLLHDICKPQCKTTDEKGIDHFYNHAELSSNKSKEILKRMKYDNNTIDKVSTLVKYHDREIGSNKSIRKLLSLIGEDNFRDLLKVKEADIKAQNLKYYDERHNKLIEIEHKLNDIISKNQCFSLKDLKVNGRDLIELGYTGKEIGHILNDLLEKVLENPDLNNKDTLIGMIR
>NC_015426.1|WP_013726781.1|69264_69909_+|hypothetical-protein
MNLKLIYLSMKNLKIYYFIPLIFLYIVIPILDIGLINMSENIENSYQLIFAEAEKYIPILSLWWSTFIFKEYIDGDGNEVLYCIGSSSKLKIQHITLIFIWYIIHVSILFLGYSFFLDNVLLEFLKTIIQCFFFSSIAYMLIYTLKSTTISFMFLLIYELLCLFVRCEFIKYMSIFEGEQILSVQLISTKYAVFFLVGILFLLIGMYKNKRFYY
>NC_015426.1|WP_013726780.1|68420_69260_+|ATP-binding-cassette-domain-containing-protein
MLEILDLHKSFKRKEILKGISINLDTGIYGLLGKNGAGKTTLMRCIVNLYNTTKGNIKFEEKDIANDTSFSNNIGYLPQKFGLFKELTVYEMMEYFAVLKKLPKESMDMYIKSSLEIVNLEDRLKDKISTLSGGMIRRLGIAQAILGDPKIIIFDEPTAGLDPEERLRFKNLLSHIKKDKIIIISTHIVEDVEACCDKIIIMDDGKMLKEGSSDAIKSVAKGKVFEIPEETKINFNHFVEKTFEKDGKRFLRILSNENQEYTGLEPTIEDGYMCLLKGI
>NC_015426.1|WP_019278497.1|66462_68406_+|ABC-transporter-permease
MTNLIKSNFKIFFRSLYLSVPLLIFFIILNGYLGVGIRNLTIHKDALFYLQYSQRISVIYFIFFTFISYEYLIKSKNSNLLESISVLNKGTLKLYFSKLIVLVAIILIMTLNIFAYNFIVYIVMKVHSTSYLLHIILNHLLNIFLVSIFAVCIGSTISLYFKRFPAYALMILSVILISPISEKVPYILHMGYNIDIYFLREPFNILPPNLNWESEYLYGLSIEPYRWNLIAFWISFLSFLMILKLSKRKYKSLNITAAILLIFSLGNFYGFTKPGSILKKDYNPKNFTAFDEIYYSDDVQKEEKALFKISEYDMKLNINRELENDIIIHLNEKEPLKTYKFTLYRNYKIKKVLGKNNETLEYKRDGDYLEVINPTNNKLNEIRIVYSGSSPVFYSNCQGVLLPGYFPYYPTEGYKRMYTDGGRFVPVIRDYTVKFNISLKSNLDIASNLDKKDSKLSGQAQEVTLMGGFLKEKSVKDNIVYELLLDKMDTSVFSHIDNNINSYNKILSSNYKFTIKSKKIFQAPTTLLNRVAYNGIADFKDHIIVPGLDANVLSLDLIQSNLLKNIKKKQISDMLFEYILDKDSFTDKKRFEEMPKEMFEDPFYQIDYLFLEKINKLGGDYVIKNSYKFLIDENDKRDAMTFVKNLK
>NC_015426.1|WP_167317602.1|65096_66032_-|hypothetical-protein
MEKEISYICNCEYEYFLNKANVVGIGCGYKVQNGFYTKKLCIQVFVSRKLPSNELNSQDIVPNLYKEIPTDVKETGYFKPCSLIQKVRPILGGYVIGNEYNTAHSGTLGCLVKDSKDLFILSNNHVLTMINQAPLGTKIIQPSCQYKGDIKTDVIGNLSKYIKIKFKGAITTPTNYTDCSIAKVIDKSLVSPKIALVGMPKGINTPKLNENVKKVGAISELTTGVITSLHTTIRVNYDILKKAAIYKEQILTTQMAEGGDSGAVLLDKNNYVVALLMSGSKNTSTFNPINTVLKQLKVSIVTSDSWNEIDK
>NC_015426.1|WP_013726790.1|77873_79892_-|CRISPR-associated-helicase/endonuclease-Cas3
MNDLNDKLKQYKAKSDGTTLFQHNQDLLVALEQLSKIHSIPQELKNSLIKCIKYHDIGKVTDDFQNNIESKHRNIRHEIISASAKDLDDNERLNILLHHRVLEKLAQFINNVYYKDSLNEVKNKLNIKVEDITSYLKKICRGGRENHKKLHNKDLIIQLGLLKMCDHIASAGINNIDIGLNTKEVFNFEKYRSIQEKVLNLKEVKDIIIQAPTGLGKTETALLWTNLVQNKFKGKRIFYILPYTASINALYKRFKEQNISVGVLHSKVQSLLSRDEDIENIEEELQLFKKNIKQVTICTIFQLLKAMFSCKNFEMILAQLKDSIIVIDEIHCFDLRTFAFMMESLKYLRENFGINICIMSASIPTCMLEFMKETLNINTLINADKEDFLIRHHINRVDKELVNDLDKIKAAIENNKQALLCVNNVAASQKLFSNLKEQYPNKNIKLIHGRFNARDRSEIEKDLKNCDVLIGTQAIEVSLDIDYDVLYTEMAPLDALLQRFGRVNRKGEKGIADVYIYNKSKEYNSIYDNNIIDKTDIELNNIIKNDSGIILEDKVNLYLDNIYTEFNIDEYNQYKKQINDIINNIRVGYYNENACEEMLSNDNSVQMIPVSLLSEYIKSREEKRYIEGNELFVNSKKYLSEYNKNLRIYITDRVYDIRGLVEKEIDIDNQMV
>NC_015426.1|WP_013726791.1|79964_80429_-|hypothetical-protein
MNYENSEQIEQIPVLIQKLYSIVNELETSFKGRKFTLDGHLVGSIGEVLVSYYYDLELLPNSTKTHDAKTKDNKLVQIKATQGKSIGISSKPNYLIVIKILPDGSIEEIYNGSGNLAWSNVGKVQKNGQCNISVNKLKNLMSEVPETSRIPKIR
>NC_015426.1|WP_013720788.1|81199_82432_-|IS256-like-element-ISCbo4-family-transposase
MRNFEVPDFDYKEEVKKCKSLDDVMGKNGLIQRMLKDVIQNILEAEMEDHLGRDKYERNSENNSKNYRNGYSKKNIRSSFGDIDVDIPRDRNAEFEPKVIKKYETVCNELDKKVIGLYARGMSTRDIQAEIEDLYGITISPSMVSKITDKVIGAATAWQNRTLDRIYPIVYMDAMHFKVRDDNRIVSKAAYICMAYDMSGHKDILGIWVGESEGAKFWLSVCNDLKNRGVKQILIACMDGLRGLPDAIKTVYPEVSIQTCIVHQIRNSLKYIASKDKKEFIKDLKLIYKATTEELALLELDNLKEKWGSKYGIVIDSWYNNWDNLSTFFEFSPEIRKMIYTTNALEGFNRQIRKFTKTRTVFPTDESLKKSLYLATMEIMEKWTSPRQNWALTLGQLTITFGNKIDEFLA
>NC_015426.1|WP_013726795.1|84312_84453_-|hypothetical-protein
MLNKNKKENKEKQDLFDLYQYDMLVDFKEFKSTKNRMTIGFMNLDK
>NC_015426.1|WP_013726796.1|84885_85545_-|hypothetical-protein
MERTYNVFIDNGLYVLANEIDKEIQDITLKDIKNSTNIFAKRFEEYASCEYYKKNVSMGFQNSAYTQALKKDKETKQENETRSEKVQNQYNLILSNMGNDEYCSICGKKHVNLNPNINYVKSFTRCWMPHIHANTFINYINNLEMVNICPVCLYLSMISIFNFEKAGDKIILYSSDDNDFMKDYTYDKQIEVKNNIAMCAKESKEKTNNIKSITEVIKK
>NC_015426.1|WP_013726797.1|85546_86302_-|CRISPR-associated-endoribonuclease-Cas6
MLSRKSIILQAQNDGVLDYNWNYPLSINLFNKMSLYDAKFAEFLHDEGFKSKDEKKKKFKLINFMLLFNNQKMDSEGININKNDESVLIISGYKDPMNAILQGLCINNEINLNNVIFKVIDVKEDKKVKFNKINIYKAMTPIVESIWEDNSVKFLNPYQSKYYDAIKQNLNRKYEIIYNKPYSGELKLMIENMLKIKQKSIRIKNGYIQGYSNFEILVQCNKNMQKVAYYCGLGQNSSMGAGLVNYITGGE
>NC_015426.1|WP_019278491.1|86280_86925_-|CRISPR-associated-protein-Cas5
MEFKKLVLTSKMAHFKNGINGKNQNTFRVPPISTIVGILKNIYGKDIKDFIFGYTCKYDGIFKDVTTIYKEVNLDISSAKGDRFQHDIAFIEYLVNPIITVYTNLDTPIKINDILNLGKTNCLAKCKFEKENITNKECIGYNQWTPINTGNGKIKRINKETIYNQNKGYYDYYTELFRLNEEFTAKHILEDQEEGIQLWQYRGVGDIECYQENL
>NC_015426.1|WP_013726799.1|87286_89005_-|hypothetical-protein
MENNEKINSKKKIINENTTVIDNNIIESPLFISSLKEVVEVEQLEKYIDKNRSIHRVIEVIKEDYEGTSNPKNYKNVPVVYRQWTDSKGLERQLLVTHAIPDMYTMDVWNALIGLYIQKISPIHFNNNKNTYDLDVNEMEFTLYELAKFMNKSTGGSTLDKLMKEIVRLNNAKYYSFANGVIFDKKKEKYLKSKTKGMSLILDCEFDSEKRVKDEKVNSKCKVEFNKLIIDNIRYQYIKYIDPKEYFALPSRGLTRRLYVYLKGNSHQSNGTKYTYIKRNFYVLKNNIPILEKQPSKIKERLKVPLKNLIKNGMITDYFYGDEDVINEQEPCIYFIFKGQKDEVINSLRKKYEEKQLQLEVAADNIKKDEFQMKIPENLDKTLEEIGFNAKVIKQLYAEYDKWEIIKYVIWLQQQQFKSKCTIQNPAGLLRFALMGNINLDLTNKDIVEFVENEQKKFIENKLSREEIVQNAYDKYVNEEMEKFKTEDNATHDIIYENTLINIEAQVDLQIAQLRLLEKNEGVEMPSLKLWEEFREKKDKSELFKKNFINSAKVLRGIMTLEEFKVEFGNDK
>NC_015426.1|WP_013726800.1|89440_90865_+|WG-repeat-containing-protein
MKKILKVFLVCMFMMFLTSCSNEKEISLPKDVNRISNVCYLGKNIYGIDIAPIPKGTFPKRNYKLINLKGNIISKEDIIYIDKECSFLDNGAVSVLNKDKKSMLISKDGKVIDDRYTIYSYLGNGVFAVSKNFKTGYCNSKGEDIVPPIDFMSICNVQKGDKFPYKNNEGKLGFIDTKGKTVIPFVFDGIGKYSKDANFISASKDKKWGLINKDGKTIIPFKFSWLFPCEDGNFIVELNNKCGLIDKNSKVIIPFEFDLILEIKKGTYKVLLIDKFNCNKLYGVMDNRGKTIVKPFEAFKIDYADNKNIVSNAVDDMGNSLEYTKMMHQLLDTNRKELTPDFYEEITYYKDDLFRVKNNNKYGFINRSGKVVIPVKFNNFLEFNDNFCIVDLNGKYGILDKSGHYKINPKYEDIKYLCKNSFAVKLNNKWGIVDSCDKLIKPIEYDDISSIESHIECKYNVLMKKGQKGILLKI
>NC_015426.1|WP_019278492.1|90965_93032_-|methyl-accepting-chemotaxis-protein
MIKKFKSIQTKFLFITILIIILALATVGITIGYQVNNQVKKDYISNSQEQMKLAERSIRIFYDQIDRNINMLASNPLIIQANKDNITSYINTTEATQMTPSKNGPIESGIYNIFEQYAKSHPGTMFVYLATKYGGYVNWPECTISKQYNPTPKAWYQTALKANGTIIRTAPYKADTGSMVISNVRCLTDSNGNVLGTIGIDVEQSVISNMLSKMKIGKTGFSMLIHNTGMVMADGNNTTNNFKNIKDVNIPGIEKVLSKDLKSFKVTIDKKQYIGSTHKIDNTDWILASFMSENELLSSAKRISSIILVISIFMLILTFILINIITKQITSPIIKSSKHLEILASGDFSQELDCKLLSREDEIGTITNGINNMKSSLMNLVVSIRNESSAIEQKVSNIVDNVKILDGDLQEISATTEELAASMEETSAVSEEMSATSQQMELSINSIAEKSEKGAVAANEINKRAAMIKENTNIAQKKAANILLHTKDQLQQAIEDSKIVDEINILSESIMQITEQTDLLALNAAIEAARAGEYGKGFSVVADEIRKLAEQSKSTVLKIQSVTTNVVSSVNNLSTNATNLLDFVSTDVANDYEVMLDVSEKYNVDAKFIDKLVAEISDTSEELLSSVQEVLGAINNVAVAANDGASGTTNIADKVSKVNYKSTEVMQEVLKSKESTDKLQQEVHKFKI

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Crispr_ID: NC_015426_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015426_3

80630-80991

Unclear

Consensus_repeat	Method
CTTTATAACTAACATAGTTCTATTAATAC	CRISPRCasFinder
CTTTATAACTAACATAGTTCTATTAATAC	CRT
CTTTATAACTAACATAGTTCTATTAATAC	PILER-CR

5 spacers

cas3,cas6

The CRISPR arrays of NC_015426_3

>merge|NC_015426|3|80630-80991|CRISPRCasFinder,CRT,PILER-CR
ACTAATAACTAACATAGTTCTATTAATACCATATCCAAGAGTACGAACTCCTACACAATCTAGATACTTTATAACTAACATAGTTCTATTAATACTTTCATGGGAAATAGCGAATTAGCCATTTCCCAATACTTTATAACTAACATAGTTCTATTAATACGAAATATATTATATAGATGTAGAATTATTGTGTCCGTGCTTTATAACTAACATAGTTCTATTAATACATATATAGAATAATATTATCCAGATAGGAGCAATGTCACTTTATAACTAACATAGTTCTATTAATACATGCATTAATGGGAATTATAGAATTAGAAGATAAGTAAGCTTTATAACTAACATAGTTCTATTAATAC

>NC_015426|3|2|80630-80991|CRISPRCasFinder
ACTAATAACTAACATAGTTCTATTAATAC	CATATCCAAGAGTACGAACTCCTACACAATCTAGATA
CTTTATAACTAACATAGTTCTATTAATAC	TTTCATGGGAAATAGCGAATTAGCCATTTCCCAATA
CTTTATAACTAACATAGTTCTATTAATAC	GAAATATATTATATAGATGTAGAATTATTGTGTCCGTG
CTTTATAACTAACATAGTTCTATTAATAC	ATATATAGAATAATATTATCCAGATAGGAGCAATGTCA
CTTTATAACTAACATAGTTCTATTAATAC	ATGCATTAATGGGAATTATAGAATTAGAAGATAAGTAAG
CTTTATAACTAACATAGTTCTATTAATAC

>NC_015426|3|3|80630-80991|CRT
ACTAATAACTAACATAGTTCTATTAATAC	CATATCCAAGAGTACGAACTCCTACACAATCTAGATA
CTTTATAACTAACATAGTTCTATTAATAC	TTTCATGGGAAATAGCGAATTAGCCATTTCCCAATA
CTTTATAACTAACATAGTTCTATTAATAC	GAAATATATTATATAGATGTAGAATTATTGTGTCCGTG
CTTTATAACTAACATAGTTCTATTAATAC	ATATATAGAATAATATTATCCAGATAGGAGCAATGTCA
CTTTATAACTAACATAGTTCTATTAATAC	ATGCATTAATGGGAATTATAGAATTAGAAGATAAGTAAG
CTTTATAACTAACATAGTTCTATTAATAC

>NC_015426|3|3|80696-80991|PILER-CR
CTTTATAACTAACATAGTTCTATTAATAC	TTTCATGGGAAATAGCGAATTAGCCATTTCCCAATA
CTTTATAACTAACATAGTTCTATTAATAC	GAAATATATTATATAGATGTAGAATTATTGTGTCCGTG
CTTTATAACTAACATAGTTCTATTAATAC	ATATATAGAATAATATTATCCAGATAGGAGCAATGTCA
CTTTATAACTAACATAGTTCTATTAATAC	ATGCATTAATGGGAATTATAGAATTAGAAGATAAGTAAG
CTTTATAACTAACATAGTTCTATTAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015426.1\|WP_013726781.1\|69264_69909_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|223690
NC_015426.1\|WP_013726803.1\|94242_95916_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09759_cas6_CAS-I-A	gnl\|CDD\|187889
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NC_015426.1\|WP_013726780.1\|68420_69260_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213231
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379719
NC_015426.1\|WP_013726796.1\|84885_85545_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_015426.1\|WP_013726799.1\|87286_89005_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|226071
NC_015426.1\|WP_039258810.1\|73909_74197_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726795.1\|84312_84453_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726784.1\|72546_73014_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278492.1\|90965_93032_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_015426.1\|WP_019278494.1\|75043_75409_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	unknown	unknown	gnl\|CDD\|273860
NC_015426.1\|WP_013726791.1\|79964_80429_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726802.1\|93062_94019_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238882
NC_015426.1\|WP_013726785.1\|73259_73640_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	gnl\|CDD\|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.54509e-06
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	5.50298e-08
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	gnl\|CDD\|226071	COG3541, COG3541, Predicted nucleotidyltransferase [General function prediction only].	6.0839e-33
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	gnl\|CDD\|223690	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis].	1.21561e-88
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.19116e-66
NC_015426.1\|WP_013726780.1\|68420_69260_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213231	cd03264, ABC_drug_resistance_like, ABC-type multidrug transport system, ATPase component. The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	6.76388e-92
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.66787e-122
NC_015426.1\|WP_019278492.1\|90965_93032_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.52903e-40
NC_015426.1\|WP_013726802.1\|93062_94019_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238882	cd01846, fatty_acyltransferase_like, Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Might catalyze fatty acid transfer between phosphatidylcholine and sterols.	6.66768e-69
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.86929e-23

>NC_015426.1|WP_013726791.1|79964_80429_-|hypothetical-protein
MNYENSEQIEQIPVLIQKLYSIVNELETSFKGRKFTLDGHLVGSIGEVLVSYYYDLELLPNSTKTHDAKTKDNKLVQIKATQGKSIGISSKPNYLIVIKILPDGSIEEIYNGSGNLAWSNVGKVQKNGQCNISVNKLKNLMSEVPETSRIPKIR
>NC_015426.1|WP_013726790.1|77873_79892_-|CRISPR-associated-helicase/endonuclease-Cas3
MNDLNDKLKQYKAKSDGTTLFQHNQDLLVALEQLSKIHSIPQELKNSLIKCIKYHDIGKVTDDFQNNIESKHRNIRHEIISASAKDLDDNERLNILLHHRVLEKLAQFINNVYYKDSLNEVKNKLNIKVEDITSYLKKICRGGRENHKKLHNKDLIIQLGLLKMCDHIASAGINNIDIGLNTKEVFNFEKYRSIQEKVLNLKEVKDIIIQAPTGLGKTETALLWTNLVQNKFKGKRIFYILPYTASINALYKRFKEQNISVGVLHSKVQSLLSRDEDIENIEEELQLFKKNIKQVTICTIFQLLKAMFSCKNFEMILAQLKDSIIVIDEIHCFDLRTFAFMMESLKYLRENFGINICIMSASIPTCMLEFMKETLNINTLINADKEDFLIRHHINRVDKELVNDLDKIKAAIENNKQALLCVNNVAASQKLFSNLKEQYPNKNIKLIHGRFNARDRSEIEKDLKNCDVLIGTQAIEVSLDIDYDVLYTEMAPLDALLQRFGRVNRKGEKGIADVYIYNKSKEYNSIYDNNIIDKTDIELNNIIKNDSGIILEDKVNLYLDNIYTEFNIDEYNQYKKQINDIINNIRVGYYNENACEEMLSNDNSVQMIPVSLLSEYIKSREEKRYIEGNELFVNSKKYLSEYNKNLRIYITDRVYDIRGLVEKEIDIDNQMV
>NC_015426.1|WP_019278494.1|75043_75409_-|hypothetical-protein
MRKVTNILTSLSLFIFSILILIDFMIIGSDIPVNIHRNEVIFFIILNVIYILLQTAYINTVKTIPRKINIYLITFVSFIWLMLLIDELTYSYHIYCRISEIIGLTSQIYILIKYIKKVYII
>NC_015426.1|WP_039258810.1|73909_74197_+|hypothetical-protein
MFKISNDTFFKICKIVSISCILISIVGWIPTFCSILTPLWMLSVLVSPIGFIFSLITLIKYNWKLGILLALLNVIMFFSFFIVMHIGYTFFYPHN
>NC_015426.1|WP_013726785.1|73259_73640_-|hypothetical-protein
MSNSLKKSVKGNIKKVITGLIFISIIIFGIAFIKNYRTNEYIIIKTMSQAQEIAIRGEYEDYTMSKNMLKDLFKDYLLGDISKNTYEPQNKLNSILYKNEYMKAKELYLKYDKLQQKCTNSNKGKK
>NC_015426.1|WP_013726784.1|72546_73014_-|hypothetical-protein
MIKLYILVFVLKLVDCMFTTTKTKALIYGYDKFAAILKGVASITNAIILMNVVIAKSYTGIIVIGVAETLGTFLATGLFNKFKKDEEWTFFVAPRTREDSKIIADTLREQGIPTYTVEGYYNKNSVLSCIVTAKTKEESKIVYKVCKDKAKCKRI
>NC_015426.1|WP_013726783.1|71454_72474_-|nucleotidyltransferase
MNIDEIKQKLRSQEYDFLRTNEHLGNNIILLTTGGSYAYGTNIDTEEHTSDLDIRGICVERPEEIIGLSSFEQFENKETDTTIYGLRKVIKLLLNCNPNVIEILGTKDEHLFICTKAGKLLRDNLDLFISKKAIASFGGYSTAQLRRLQNALARDSYPQKEKEEHILKSIESQMLTMKDRYKEVKNEELKLYIDKSDKEDLESEIFIDISLKHYPLRDFKNIYSEMTQIVKDYDKLTHRNSKKDTLHLNKHAMHLIRLLLMGTEILEGKGVNTHREKDIELLLNIRNGKYSYNEIFEMVNDYDKQFKYAAEHTELQNNPDYKKVEELVMEINRGVINGQ
>NC_015426.1|WP_019278496.1|70130_71465_-|HD-domain-containing-protein
MDNNMEIKMPKCVGYIIHKLQEFNYEAYIVGGCVRDSLLKKTPNDWDITTSALPNKVVDIFQNLGYKIIPTGLKHGTVTIVINNEHYEVTTYRIDGEYEDNRHPKKVEFTRNLKEDLSRRDFTINSMAYNDKDGLVDYFNSKNDLESGIVKSVGDPMKRFSEDALRILRAYRFAAQLGFVIEDETLSATMQVKDNLKSISIERIRDEIDKMLLANSSIFFELSKFGVLEVILPELYQCFNVEQNNPYHVKNVFNHIINATLNIEPKLHLKLTMLLHDICKPQCKTTDEKGIDHFYNHAELSSNKSKEILKRMKYDNNTIDKVSTLVKYHDREIGSNKSIRKLLSLIGEDNFRDLLKVKEADIKAQNLKYYDERHNKLIEIEHKLNDIISKNQCFSLKDLKVNGRDLIELGYTGKEIGHILNDLLEKVLENPDLNNKDTLIGMIR
>NC_015426.1|WP_013726781.1|69264_69909_+|hypothetical-protein
MNLKLIYLSMKNLKIYYFIPLIFLYIVIPILDIGLINMSENIENSYQLIFAEAEKYIPILSLWWSTFIFKEYIDGDGNEVLYCIGSSSKLKIQHITLIFIWYIIHVSILFLGYSFFLDNVLLEFLKTIIQCFFFSSIAYMLIYTLKSTTISFMFLLIYELLCLFVRCEFIKYMSIFEGEQILSVQLISTKYAVFFLVGILFLLIGMYKNKRFYY
>NC_015426.1|WP_013726780.1|68420_69260_+|ATP-binding-cassette-domain-containing-protein
MLEILDLHKSFKRKEILKGISINLDTGIYGLLGKNGAGKTTLMRCIVNLYNTTKGNIKFEEKDIANDTSFSNNIGYLPQKFGLFKELTVYEMMEYFAVLKKLPKESMDMYIKSSLEIVNLEDRLKDKISTLSGGMIRRLGIAQAILGDPKIIIFDEPTAGLDPEERLRFKNLLSHIKKDKIIIISTHIVEDVEACCDKIIIMDDGKMLKEGSSDAIKSVAKGKVFEIPEETKINFNHFVEKTFEKDGKRFLRILSNENQEYTGLEPTIEDGYMCLLKGI
>NC_015426.1|WP_013720788.1|81199_82432_-|IS256-like-element-ISCbo4-family-transposase
MRNFEVPDFDYKEEVKKCKSLDDVMGKNGLIQRMLKDVIQNILEAEMEDHLGRDKYERNSENNSKNYRNGYSKKNIRSSFGDIDVDIPRDRNAEFEPKVIKKYETVCNELDKKVIGLYARGMSTRDIQAEIEDLYGITISPSMVSKITDKVIGAATAWQNRTLDRIYPIVYMDAMHFKVRDDNRIVSKAAYICMAYDMSGHKDILGIWVGESEGAKFWLSVCNDLKNRGVKQILIACMDGLRGLPDAIKTVYPEVSIQTCIVHQIRNSLKYIASKDKKEFIKDLKLIYKATTEELALLELDNLKEKWGSKYGIVIDSWYNNWDNLSTFFEFSPEIRKMIYTTNALEGFNRQIRKFTKTRTVFPTDESLKKSLYLATMEIMEKWTSPRQNWALTLGQLTITFGNKIDEFLA
>NC_015426.1|WP_013726795.1|84312_84453_-|hypothetical-protein
MLNKNKKENKEKQDLFDLYQYDMLVDFKEFKSTKNRMTIGFMNLDK
>NC_015426.1|WP_013726796.1|84885_85545_-|hypothetical-protein
MERTYNVFIDNGLYVLANEIDKEIQDITLKDIKNSTNIFAKRFEEYASCEYYKKNVSMGFQNSAYTQALKKDKETKQENETRSEKVQNQYNLILSNMGNDEYCSICGKKHVNLNPNINYVKSFTRCWMPHIHANTFINYINNLEMVNICPVCLYLSMISIFNFEKAGDKIILYSSDDNDFMKDYTYDKQIEVKNNIAMCAKESKEKTNNIKSITEVIKK
>NC_015426.1|WP_013726797.1|85546_86302_-|CRISPR-associated-endoribonuclease-Cas6
MLSRKSIILQAQNDGVLDYNWNYPLSINLFNKMSLYDAKFAEFLHDEGFKSKDEKKKKFKLINFMLLFNNQKMDSEGININKNDESVLIISGYKDPMNAILQGLCINNEINLNNVIFKVIDVKEDKKVKFNKINIYKAMTPIVESIWEDNSVKFLNPYQSKYYDAIKQNLNRKYEIIYNKPYSGELKLMIENMLKIKQKSIRIKNGYIQGYSNFEILVQCNKNMQKVAYYCGLGQNSSMGAGLVNYITGGE
>NC_015426.1|WP_019278491.1|86280_86925_-|CRISPR-associated-protein-Cas5
MEFKKLVLTSKMAHFKNGINGKNQNTFRVPPISTIVGILKNIYGKDIKDFIFGYTCKYDGIFKDVTTIYKEVNLDISSAKGDRFQHDIAFIEYLVNPIITVYTNLDTPIKINDILNLGKTNCLAKCKFEKENITNKECIGYNQWTPINTGNGKIKRINKETIYNQNKGYYDYYTELFRLNEEFTAKHILEDQEEGIQLWQYRGVGDIECYQENL
>NC_015426.1|WP_013726799.1|87286_89005_-|hypothetical-protein
MENNEKINSKKKIINENTTVIDNNIIESPLFISSLKEVVEVEQLEKYIDKNRSIHRVIEVIKEDYEGTSNPKNYKNVPVVYRQWTDSKGLERQLLVTHAIPDMYTMDVWNALIGLYIQKISPIHFNNNKNTYDLDVNEMEFTLYELAKFMNKSTGGSTLDKLMKEIVRLNNAKYYSFANGVIFDKKKEKYLKSKTKGMSLILDCEFDSEKRVKDEKVNSKCKVEFNKLIIDNIRYQYIKYIDPKEYFALPSRGLTRRLYVYLKGNSHQSNGTKYTYIKRNFYVLKNNIPILEKQPSKIKERLKVPLKNLIKNGMITDYFYGDEDVINEQEPCIYFIFKGQKDEVINSLRKKYEEKQLQLEVAADNIKKDEFQMKIPENLDKTLEEIGFNAKVIKQLYAEYDKWEIIKYVIWLQQQQFKSKCTIQNPAGLLRFALMGNINLDLTNKDIVEFVENEQKKFIENKLSREEIVQNAYDKYVNEEMEKFKTEDNATHDIIYENTLINIEAQVDLQIAQLRLLEKNEGVEMPSLKLWEEFREKKDKSELFKKNFINSAKVLRGIMTLEEFKVEFGNDK
>NC_015426.1|WP_013726800.1|89440_90865_+|WG-repeat-containing-protein
MKKILKVFLVCMFMMFLTSCSNEKEISLPKDVNRISNVCYLGKNIYGIDIAPIPKGTFPKRNYKLINLKGNIISKEDIIYIDKECSFLDNGAVSVLNKDKKSMLISKDGKVIDDRYTIYSYLGNGVFAVSKNFKTGYCNSKGEDIVPPIDFMSICNVQKGDKFPYKNNEGKLGFIDTKGKTVIPFVFDGIGKYSKDANFISASKDKKWGLINKDGKTIIPFKFSWLFPCEDGNFIVELNNKCGLIDKNSKVIIPFEFDLILEIKKGTYKVLLIDKFNCNKLYGVMDNRGKTIVKPFEAFKIDYADNKNIVSNAVDDMGNSLEYTKMMHQLLDTNRKELTPDFYEEITYYKDDLFRVKNNNKYGFINRSGKVVIPVKFNNFLEFNDNFCIVDLNGKYGILDKSGHYKINPKYEDIKYLCKNSFAVKLNNKWGIVDSCDKLIKPIEYDDISSIESHIECKYNVLMKKGQKGILLKI
>NC_015426.1|WP_019278492.1|90965_93032_-|methyl-accepting-chemotaxis-protein
MIKKFKSIQTKFLFITILIIILALATVGITIGYQVNNQVKKDYISNSQEQMKLAERSIRIFYDQIDRNINMLASNPLIIQANKDNITSYINTTEATQMTPSKNGPIESGIYNIFEQYAKSHPGTMFVYLATKYGGYVNWPECTISKQYNPTPKAWYQTALKANGTIIRTAPYKADTGSMVISNVRCLTDSNGNVLGTIGIDVEQSVISNMLSKMKIGKTGFSMLIHNTGMVMADGNNTTNNFKNIKDVNIPGIEKVLSKDLKSFKVTIDKKQYIGSTHKIDNTDWILASFMSENELLSSAKRISSIILVISIFMLILTFILINIITKQITSPIIKSSKHLEILASGDFSQELDCKLLSREDEIGTITNGINNMKSSLMNLVVSIRNESSAIEQKVSNIVDNVKILDGDLQEISATTEELAASMEETSAVSEEMSATSQQMELSINSIAEKSEKGAVAANEINKRAAMIKENTNIAQKKAANILLHTKDQLQQAIEDSKIVDEINILSESIMQITEQTDLLALNAAIEAARAGEYGKGFSVVADEIRKLAEQSKSTVLKIQSVTTNVVSSVNNLSTNATNLLDFVSTDVANDYEVMLDVSEKYNVDAKFIDKLVAEISDTSEELLSSVQEVLGAINNVAVAANDGASGTTNIADKVSKVNYKSTEVMQEVLKSKESTDKLQQEVHKFKI
>NC_015426.1|WP_013726802.1|93062_94019_-|SGNH/GDSL-hydrolase-family-protein
MKKKFVFMFTIILTCIVVFGGIKYLTSRKKISEKITQVVAFGDSYSDNGQAKKISTQIMADPNRPKEAYLKPSDKLYWNGRYSNGNTAVEVLSQKLGVPLTNYATGGATTGEKNYSDWTDYLGNTGVLGQIEKFKKSLKTDNADPDALYFIFASANDYFKFMDYSMPGKIETVADNAVNNINTAVKTLAGLGAKKFFVVNSSDLTLVPYEITNNRTKSAAVFVNRVNKKLPESLKELQKNLNVKIMMFDLPKISDKIMKNPSKYGLVELKKECQSTYPKVKPACDNQDQYYFWDEWHYSRAVHKILGGEMYSKVKMFK
>NC_015426.1|WP_013726803.1|94242_95916_-|hypothetical-protein
MSEKSKALQKQSFIMDINILEAPFFLFNQSTKAVKVKDVKNNPNITDEVRHILEVHGIDQGESKYFNWKDSKGMTREMLALTTGQLPRKFTMDVWYGIVGLYIKKTSPINFNEQLNMFDIQSDRLYFTLYELAKFMKLTTGGSNIAKIQDAIRQLKNTQYYSFSNGSIYDKKNEEYIKTKERGLSLVLEYEFNSEKKRSSKQDMKYKCWVQLNSLVIDNIKHEFIKYLNSETYFTLPSGLTRGLYTYLEGNKYSSNGMLTYIKRNFEVLANKIPIEYKFNSDLKKKLKKPLENLIKYGIISDYFYGDKYIINKKEPCIYFIFKGKKEEIINTLRQKYEEKQLLLEVATDNIKKDEFEMEIPENLDKTLEEIGFNAKVIKQLYAEHDKWDIVKYVIWLQQQKSKNTGSVKNSAGLLRFALMGNVNLEISHKDIVEFVENQKEKFEENKISRQEILKNAYDKYVNDEIEKLKKEEDGTYNIIYENTLINIEAQVDAQIAQLRLLEKNEGVEMPSLKLWEEFKEKKEKSELFKKNFINSIKVFRGIMTLEEFKIEFEKDK

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Crispr_ID: NC_015426_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015426_4

82553-83044

Unclear

Consensus_repeat	Method
CTTTATAACTAACATAGTTCTATTAATAC	PILER-CR
CTTTATAACTAACATAGTTCTATTAATAC	CRISPRCasFinder
CTTTATAACTAACATAGTTCTATTAATAC	CRT

7 spacers

cas3,cas6

The CRISPR arrays of NC_015426_4

>merge|NC_015426|4|82553-83044|PILER-CR,CRISPRCasFinder,CRT
CTTTATAACTAACATAGTTCTATTAATACGTTTAAATTTAATAAAAATTCTGGTTGTGTAAAGGTACTTTATAACTAACATAGTTCTATTAATACTAAAACAGTTGGAATGACAATCGTTACTTCCGCTATCTTTATAACTAACATAGTTCTATTAATACGCTCAGGGTCAACTCAGCAAGTTGCTAGAAGGTGCACTTTATAACTAACATAGTTCTATTAATACAATTACTTTTAATAATAACGGTGATATAAAAGACAGCTTTATAACTAACATAGTTCTATTAATACCTAACCATTCTGGTCCCAAATCTAACATTGATTTAGATACCTTTATAACTAACATAGTTCTATTAATACCAAAATTATTATCACCTATTTCTATAACACCTTCTGACTTTATAACTAACATAGTTCTATTAATACTTTATTACCACTTAATGCTATTCTTACTTTATCTCCAACTTTATAACTAACATAGTTCTATTAATAC

>NC_015426|4|4|82553-82977|PILER-CR
CTTTATAACTAACATAGTTCTATTAATAC	GTTTAAATTTAATAAAAATTCTGGTTGTGTAAAGGTA
CTTTATAACTAACATAGTTCTATTAATAC	TAAAACAGTTGGAATGACAATCGTTACTTCCGCTAT
CTTTATAACTAACATAGTTCTATTAATAC	GCTCAGGGTCAACTCAGCAAGTTGCTAGAAGGTGCA
CTTTATAACTAACATAGTTCTATTAATAC	AATTACTTTTAATAATAACGGTGATATAAAAGACAG
CTTTATAACTAACATAGTTCTATTAATAC	CTAACCATTCTGGTCCCAAATCTAACATTGATTTAGATAC
CTTTATAACTAACATAGTTCTATTAATAC	CAAAATTATTATCACCTATTTCTATAACACCTTCTGA
CTTTATAACTAACATAGTTCTATTAATAC

>NC_015426|4|3|82553-83044|CRISPRCasFinder
CTTTATAACTAACATAGTTCTATTAATAC	GTTTAAATTTAATAAAAATTCTGGTTGTGTAAAGGTA
CTTTATAACTAACATAGTTCTATTAATAC	TAAAACAGTTGGAATGACAATCGTTACTTCCGCTAT
CTTTATAACTAACATAGTTCTATTAATAC	GCTCAGGGTCAACTCAGCAAGTTGCTAGAAGGTGCA
CTTTATAACTAACATAGTTCTATTAATAC	AATTACTTTTAATAATAACGGTGATATAAAAGACAG
CTTTATAACTAACATAGTTCTATTAATAC	CTAACCATTCTGGTCCCAAATCTAACATTGATTTAGATAC
CTTTATAACTAACATAGTTCTATTAATAC	CAAAATTATTATCACCTATTTCTATAACACCTTCTGA
CTTTATAACTAACATAGTTCTATTAATAC	TTTATTACCACTTAATGCTATTCTTACTTTATCTCCAA
CTTTATAACTAACATAGTTCTATTAATAC

>NC_015426|4|4|82553-83044|CRT
CTTTATAACTAACATAGTTCTATTAATAC	GTTTAAATTTAATAAAAATTCTGGTTGTGTAAAGGTA
CTTTATAACTAACATAGTTCTATTAATAC	TAAAACAGTTGGAATGACAATCGTTACTTCCGCTAT
CTTTATAACTAACATAGTTCTATTAATAC	GCTCAGGGTCAACTCAGCAAGTTGCTAGAAGGTGCA
CTTTATAACTAACATAGTTCTATTAATAC	AATTACTTTTAATAATAACGGTGATATAAAAGACAG
CTTTATAACTAACATAGTTCTATTAATAC	CTAACCATTCTGGTCCCAAATCTAACATTGATTTAGATAC
CTTTATAACTAACATAGTTCTATTAATAC	CAAAATTATTATCACCTATTTCTATAACACCTTCTGA
CTTTATAACTAACATAGTTCTATTAATAC	TTTATTACCACTTAATGCTATTCTTACTTTATCTCCAA
CTTTATAACTAACATAGTTCTATTAATAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015426.1\|WP_013726781.1\|69264_69909_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|223690
NC_015426.1\|WP_013726803.1\|94242_95916_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09759_cas6_CAS-I-A	gnl\|CDD\|187889
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NC_015426.1\|WP_039258810.1\|73909_74197_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726796.1\|84885_85545_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	unknown	unknown	gnl\|CDD\|226071
NC_015426.1\|WP_013726799.1\|87286_89005_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	unknown	unknown	gnl\|CDD\|273860
NC_015426.1\|WP_013726804.1\|96787_97738_+\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726795.1\|84312_84453_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726784.1\|72546_73014_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_019278492.1\|90965_93032_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_015426.1\|WP_019278494.1\|75043_75409_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379719
NC_015426.1\|WP_013726791.1\|79964_80429_-\|hypothetical-protein	unknown	unknown	unknown
NC_015426.1\|WP_013726802.1\|93062_94019_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238882
NC_015426.1\|WP_013726785.1\|73259_73640_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015426.1\|WP_019278491.1\|86280_86925_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	5.50298e-08
NC_015426.1\|WP_019278496.1\|70130_71465_-\|HD-domain-containing-protein	gnl\|CDD\|223690	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis].	1.21561e-88
NC_015426.1\|WP_013726797.1\|85546_86302_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.86929e-23
NC_015426.1\|WP_013726790.1\|77873_79892_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	7.19116e-66
NC_015426.1\|WP_013726802.1\|93062_94019_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238882	cd01846, fatty_acyltransferase_like, Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Might catalyze fatty acid transfer between phosphatidylcholine and sterols.	6.66768e-69
NC_015426.1\|WP_013720788.1\|81199_82432_-\|IS256-like-element-ISCbo4-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	4.66787e-122
NC_015426.1\|WP_019278492.1\|90965_93032_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.52903e-40
NC_015426.1\|WP_013726783.1\|71454_72474_-\|nucleotidyltransferase	gnl\|CDD\|226071	COG3541, COG3541, Predicted nucleotidyltransferase [General function prediction only].	6.0839e-33
NC_015426.1\|WP_013726800.1\|89440_90865_+\|WG-repeat-containing-protein	gnl\|CDD\|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.54509e-06

>NC_015426.1|WP_013720788.1|81199_82432_-|IS256-like-element-ISCbo4-family-transposase
MRNFEVPDFDYKEEVKKCKSLDDVMGKNGLIQRMLKDVIQNILEAEMEDHLGRDKYERNSENNSKNYRNGYSKKNIRSSFGDIDVDIPRDRNAEFEPKVIKKYETVCNELDKKVIGLYARGMSTRDIQAEIEDLYGITISPSMVSKITDKVIGAATAWQNRTLDRIYPIVYMDAMHFKVRDDNRIVSKAAYICMAYDMSGHKDILGIWVGESEGAKFWLSVCNDLKNRGVKQILIACMDGLRGLPDAIKTVYPEVSIQTCIVHQIRNSLKYIASKDKKEFIKDLKLIYKATTEELALLELDNLKEKWGSKYGIVIDSWYNNWDNLSTFFEFSPEIRKMIYTTNALEGFNRQIRKFTKTRTVFPTDESLKKSLYLATMEIMEKWTSPRQNWALTLGQLTITFGNKIDEFLA
>NC_015426.1|WP_013726791.1|79964_80429_-|hypothetical-protein
MNYENSEQIEQIPVLIQKLYSIVNELETSFKGRKFTLDGHLVGSIGEVLVSYYYDLELLPNSTKTHDAKTKDNKLVQIKATQGKSIGISSKPNYLIVIKILPDGSIEEIYNGSGNLAWSNVGKVQKNGQCNISVNKLKNLMSEVPETSRIPKIR
>NC_015426.1|WP_013726790.1|77873_79892_-|CRISPR-associated-helicase/endonuclease-Cas3
MNDLNDKLKQYKAKSDGTTLFQHNQDLLVALEQLSKIHSIPQELKNSLIKCIKYHDIGKVTDDFQNNIESKHRNIRHEIISASAKDLDDNERLNILLHHRVLEKLAQFINNVYYKDSLNEVKNKLNIKVEDITSYLKKICRGGRENHKKLHNKDLIIQLGLLKMCDHIASAGINNIDIGLNTKEVFNFEKYRSIQEKVLNLKEVKDIIIQAPTGLGKTETALLWTNLVQNKFKGKRIFYILPYTASINALYKRFKEQNISVGVLHSKVQSLLSRDEDIENIEEELQLFKKNIKQVTICTIFQLLKAMFSCKNFEMILAQLKDSIIVIDEIHCFDLRTFAFMMESLKYLRENFGINICIMSASIPTCMLEFMKETLNINTLINADKEDFLIRHHINRVDKELVNDLDKIKAAIENNKQALLCVNNVAASQKLFSNLKEQYPNKNIKLIHGRFNARDRSEIEKDLKNCDVLIGTQAIEVSLDIDYDVLYTEMAPLDALLQRFGRVNRKGEKGIADVYIYNKSKEYNSIYDNNIIDKTDIELNNIIKNDSGIILEDKVNLYLDNIYTEFNIDEYNQYKKQINDIINNIRVGYYNENACEEMLSNDNSVQMIPVSLLSEYIKSREEKRYIEGNELFVNSKKYLSEYNKNLRIYITDRVYDIRGLVEKEIDIDNQMV
>NC_015426.1|WP_019278494.1|75043_75409_-|hypothetical-protein
MRKVTNILTSLSLFIFSILILIDFMIIGSDIPVNIHRNEVIFFIILNVIYILLQTAYINTVKTIPRKINIYLITFVSFIWLMLLIDELTYSYHIYCRISEIIGLTSQIYILIKYIKKVYII
>NC_015426.1|WP_039258810.1|73909_74197_+|hypothetical-protein
MFKISNDTFFKICKIVSISCILISIVGWIPTFCSILTPLWMLSVLVSPIGFIFSLITLIKYNWKLGILLALLNVIMFFSFFIVMHIGYTFFYPHN
>NC_015426.1|WP_013726785.1|73259_73640_-|hypothetical-protein
MSNSLKKSVKGNIKKVITGLIFISIIIFGIAFIKNYRTNEYIIIKTMSQAQEIAIRGEYEDYTMSKNMLKDLFKDYLLGDISKNTYEPQNKLNSILYKNEYMKAKELYLKYDKLQQKCTNSNKGKK
>NC_015426.1|WP_013726784.1|72546_73014_-|hypothetical-protein
MIKLYILVFVLKLVDCMFTTTKTKALIYGYDKFAAILKGVASITNAIILMNVVIAKSYTGIIVIGVAETLGTFLATGLFNKFKKDEEWTFFVAPRTREDSKIIADTLREQGIPTYTVEGYYNKNSVLSCIVTAKTKEESKIVYKVCKDKAKCKRI
>NC_015426.1|WP_013726783.1|71454_72474_-|nucleotidyltransferase
MNIDEIKQKLRSQEYDFLRTNEHLGNNIILLTTGGSYAYGTNIDTEEHTSDLDIRGICVERPEEIIGLSSFEQFENKETDTTIYGLRKVIKLLLNCNPNVIEILGTKDEHLFICTKAGKLLRDNLDLFISKKAIASFGGYSTAQLRRLQNALARDSYPQKEKEEHILKSIESQMLTMKDRYKEVKNEELKLYIDKSDKEDLESEIFIDISLKHYPLRDFKNIYSEMTQIVKDYDKLTHRNSKKDTLHLNKHAMHLIRLLLMGTEILEGKGVNTHREKDIELLLNIRNGKYSYNEIFEMVNDYDKQFKYAAEHTELQNNPDYKKVEELVMEINRGVINGQ
>NC_015426.1|WP_019278496.1|70130_71465_-|HD-domain-containing-protein
MDNNMEIKMPKCVGYIIHKLQEFNYEAYIVGGCVRDSLLKKTPNDWDITTSALPNKVVDIFQNLGYKIIPTGLKHGTVTIVINNEHYEVTTYRIDGEYEDNRHPKKVEFTRNLKEDLSRRDFTINSMAYNDKDGLVDYFNSKNDLESGIVKSVGDPMKRFSEDALRILRAYRFAAQLGFVIEDETLSATMQVKDNLKSISIERIRDEIDKMLLANSSIFFELSKFGVLEVILPELYQCFNVEQNNPYHVKNVFNHIINATLNIEPKLHLKLTMLLHDICKPQCKTTDEKGIDHFYNHAELSSNKSKEILKRMKYDNNTIDKVSTLVKYHDREIGSNKSIRKLLSLIGEDNFRDLLKVKEADIKAQNLKYYDERHNKLIEIEHKLNDIISKNQCFSLKDLKVNGRDLIELGYTGKEIGHILNDLLEKVLENPDLNNKDTLIGMIR
>NC_015426.1|WP_013726781.1|69264_69909_+|hypothetical-protein
MNLKLIYLSMKNLKIYYFIPLIFLYIVIPILDIGLINMSENIENSYQLIFAEAEKYIPILSLWWSTFIFKEYIDGDGNEVLYCIGSSSKLKIQHITLIFIWYIIHVSILFLGYSFFLDNVLLEFLKTIIQCFFFSSIAYMLIYTLKSTTISFMFLLIYELLCLFVRCEFIKYMSIFEGEQILSVQLISTKYAVFFLVGILFLLIGMYKNKRFYY
>NC_015426.1|WP_013726795.1|84312_84453_-|hypothetical-protein
MLNKNKKENKEKQDLFDLYQYDMLVDFKEFKSTKNRMTIGFMNLDK
>NC_015426.1|WP_013726796.1|84885_85545_-|hypothetical-protein
MERTYNVFIDNGLYVLANEIDKEIQDITLKDIKNSTNIFAKRFEEYASCEYYKKNVSMGFQNSAYTQALKKDKETKQENETRSEKVQNQYNLILSNMGNDEYCSICGKKHVNLNPNINYVKSFTRCWMPHIHANTFINYINNLEMVNICPVCLYLSMISIFNFEKAGDKIILYSSDDNDFMKDYTYDKQIEVKNNIAMCAKESKEKTNNIKSITEVIKK
>NC_015426.1|WP_013726797.1|85546_86302_-|CRISPR-associated-endoribonuclease-Cas6
MLSRKSIILQAQNDGVLDYNWNYPLSINLFNKMSLYDAKFAEFLHDEGFKSKDEKKKKFKLINFMLLFNNQKMDSEGININKNDESVLIISGYKDPMNAILQGLCINNEINLNNVIFKVIDVKEDKKVKFNKINIYKAMTPIVESIWEDNSVKFLNPYQSKYYDAIKQNLNRKYEIIYNKPYSGELKLMIENMLKIKQKSIRIKNGYIQGYSNFEILVQCNKNMQKVAYYCGLGQNSSMGAGLVNYITGGE
>NC_015426.1|WP_019278491.1|86280_86925_-|CRISPR-associated-protein-Cas5
MEFKKLVLTSKMAHFKNGINGKNQNTFRVPPISTIVGILKNIYGKDIKDFIFGYTCKYDGIFKDVTTIYKEVNLDISSAKGDRFQHDIAFIEYLVNPIITVYTNLDTPIKINDILNLGKTNCLAKCKFEKENITNKECIGYNQWTPINTGNGKIKRINKETIYNQNKGYYDYYTELFRLNEEFTAKHILEDQEEGIQLWQYRGVGDIECYQENL
>NC_015426.1|WP_013726799.1|87286_89005_-|hypothetical-protein
MENNEKINSKKKIINENTTVIDNNIIESPLFISSLKEVVEVEQLEKYIDKNRSIHRVIEVIKEDYEGTSNPKNYKNVPVVYRQWTDSKGLERQLLVTHAIPDMYTMDVWNALIGLYIQKISPIHFNNNKNTYDLDVNEMEFTLYELAKFMNKSTGGSTLDKLMKEIVRLNNAKYYSFANGVIFDKKKEKYLKSKTKGMSLILDCEFDSEKRVKDEKVNSKCKVEFNKLIIDNIRYQYIKYIDPKEYFALPSRGLTRRLYVYLKGNSHQSNGTKYTYIKRNFYVLKNNIPILEKQPSKIKERLKVPLKNLIKNGMITDYFYGDEDVINEQEPCIYFIFKGQKDEVINSLRKKYEEKQLQLEVAADNIKKDEFQMKIPENLDKTLEEIGFNAKVIKQLYAEYDKWEIIKYVIWLQQQQFKSKCTIQNPAGLLRFALMGNINLDLTNKDIVEFVENEQKKFIENKLSREEIVQNAYDKYVNEEMEKFKTEDNATHDIIYENTLINIEAQVDLQIAQLRLLEKNEGVEMPSLKLWEEFREKKDKSELFKKNFINSAKVLRGIMTLEEFKVEFGNDK
>NC_015426.1|WP_013726800.1|89440_90865_+|WG-repeat-containing-protein
MKKILKVFLVCMFMMFLTSCSNEKEISLPKDVNRISNVCYLGKNIYGIDIAPIPKGTFPKRNYKLINLKGNIISKEDIIYIDKECSFLDNGAVSVLNKDKKSMLISKDGKVIDDRYTIYSYLGNGVFAVSKNFKTGYCNSKGEDIVPPIDFMSICNVQKGDKFPYKNNEGKLGFIDTKGKTVIPFVFDGIGKYSKDANFISASKDKKWGLINKDGKTIIPFKFSWLFPCEDGNFIVELNNKCGLIDKNSKVIIPFEFDLILEIKKGTYKVLLIDKFNCNKLYGVMDNRGKTIVKPFEAFKIDYADNKNIVSNAVDDMGNSLEYTKMMHQLLDTNRKELTPDFYEEITYYKDDLFRVKNNNKYGFINRSGKVVIPVKFNNFLEFNDNFCIVDLNGKYGILDKSGHYKINPKYEDIKYLCKNSFAVKLNNKWGIVDSCDKLIKPIEYDDISSIESHIECKYNVLMKKGQKGILLKI
>NC_015426.1|WP_019278492.1|90965_93032_-|methyl-accepting-chemotaxis-protein
MIKKFKSIQTKFLFITILIIILALATVGITIGYQVNNQVKKDYISNSQEQMKLAERSIRIFYDQIDRNINMLASNPLIIQANKDNITSYINTTEATQMTPSKNGPIESGIYNIFEQYAKSHPGTMFVYLATKYGGYVNWPECTISKQYNPTPKAWYQTALKANGTIIRTAPYKADTGSMVISNVRCLTDSNGNVLGTIGIDVEQSVISNMLSKMKIGKTGFSMLIHNTGMVMADGNNTTNNFKNIKDVNIPGIEKVLSKDLKSFKVTIDKKQYIGSTHKIDNTDWILASFMSENELLSSAKRISSIILVISIFMLILTFILINIITKQITSPIIKSSKHLEILASGDFSQELDCKLLSREDEIGTITNGINNMKSSLMNLVVSIRNESSAIEQKVSNIVDNVKILDGDLQEISATTEELAASMEETSAVSEEMSATSQQMELSINSIAEKSEKGAVAANEINKRAAMIKENTNIAQKKAANILLHTKDQLQQAIEDSKIVDEINILSESIMQITEQTDLLALNAAIEAARAGEYGKGFSVVADEIRKLAEQSKSTVLKIQSVTTNVVSSVNNLSTNATNLLDFVSTDVANDYEVMLDVSEKYNVDAKFIDKLVAEISDTSEELLSSVQEVLGAINNVAVAANDGASGTTNIADKVSKVNYKSTEVMQEVLKSKESTDKLQQEVHKFKI
>NC_015426.1|WP_013726802.1|93062_94019_-|SGNH/GDSL-hydrolase-family-protein
MKKKFVFMFTIILTCIVVFGGIKYLTSRKKISEKITQVVAFGDSYSDNGQAKKISTQIMADPNRPKEAYLKPSDKLYWNGRYSNGNTAVEVLSQKLGVPLTNYATGGATTGEKNYSDWTDYLGNTGVLGQIEKFKKSLKTDNADPDALYFIFASANDYFKFMDYSMPGKIETVADNAVNNINTAVKTLAGLGAKKFFVVNSSDLTLVPYEITNNRTKSAAVFVNRVNKKLPESLKELQKNLNVKIMMFDLPKISDKIMKNPSKYGLVELKKECQSTYPKVKPACDNQDQYYFWDEWHYSRAVHKILGGEMYSKVKMFK
>NC_015426.1|WP_013726803.1|94242_95916_-|hypothetical-protein
MSEKSKALQKQSFIMDINILEAPFFLFNQSTKAVKVKDVKNNPNITDEVRHILEVHGIDQGESKYFNWKDSKGMTREMLALTTGQLPRKFTMDVWYGIVGLYIKKTSPINFNEQLNMFDIQSDRLYFTLYELAKFMKLTTGGSNIAKIQDAIRQLKNTQYYSFSNGSIYDKKNEEYIKTKERGLSLVLEYEFNSEKKRSSKQDMKYKCWVQLNSLVIDNIKHEFIKYLNSETYFTLPSGLTRGLYTYLEGNKYSSNGMLTYIKRNFEVLANKIPIEYKFNSDLKKKLKKPLENLIKYGIISDYFYGDKYIINKKEPCIYFIFKGKKEEIINTLRQKYEEKQLLLEVATDNIKKDEFEMEIPENLDKTLEEIGFNAKVIKQLYAEHDKWDIVKYVIWLQQQKSKNTGSVKNSAGLLRFALMGNVNLEISHKDIVEFVENQKEKFEENKISRQEILKNAYDKYVNDEIEKLKKEEDGTYNIIYENTLINIEAQVDAQIAQLRLLEKNEGVEMPSLKLWEEFKEKKEKSELFKKNFINSIKVFRGIMTLEEFKIEFEKDK
>NC_015426.1|WP_013726804.1|96787_97738_+|hypothetical-protein
MVLNNNCCTSNNKENKLQQNIANICDCEYKYFLNKRNVVGVGLGYKIKNGFYTNQLCVQVFVSRKLPQNQLNSNDMIPVIYKGIPTDVKETGCFTACSFNKKIRPVLGGYSISANMNKINGTVACLVTNGVSKFALSTNHVLANINILPMKSPIVQPAYLYGGHAPTDTIASLHKYIPIRFIKGHEEPTNSTDCALGLLSKSNILSDKIALIGKVTCVKSPKLNEQVRKIGASTELTTGTITSINTTFRVNYSDDKRVLFKDQILTTHMGADGDSGSILVNKNNCAVGLLFSASPNMTGFNRLSTVLDQLDVHLPK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015426_1	1.1\|74365\|34\|NC_015426\|PILER-CR,CRT	74365-74398	34	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	74365-74398	0	1.0
NC_015426_1	1.2\|74429\|36\|NC_015426\|PILER-CR,CRT	74429-74464	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	74429-74464	0	1.0
NC_015426_1	1.3\|74495\|36\|NC_015426\|PILER-CR,CRT	74495-74530	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	74495-74530	0	1.0
NC_015426_1	1.4\|74561\|36\|NC_015426\|PILER-CR,CRT	74561-74596	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	74561-74596	0	1.0
NC_015426_1	1.5\|74627\|35\|NC_015426\|PILER-CR,CRT	74627-74661	35	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	74627-74661	0	1.0
NC_015426_2	2.1\|75832\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	75832-75867	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	75832-75867	0	1.0
NC_015426_2	2.2\|75897\|38\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	75897-75934	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	75897-75934	0	1.0
NC_015426_2	2.3\|75964\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	75964-76000	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	75964-76000	0	1.0
NC_015426_2	2.4\|76030\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76030-76065	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76030-76065	0	1.0
NC_015426_2	2.5\|76095\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76095-76131	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76095-76131	0	1.0
NC_015426_2	2.6\|76161\|38\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76161-76198	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76161-76198	0	1.0
NC_015426_2	2.7\|76228\|38\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76228-76265	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76228-76265	0	1.0
NC_015426_2	2.8\|76295\|38\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76295-76332	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76295-76332	0	1.0
NC_015426_2	2.9\|76362\|35\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76362-76396	35	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76362-76396	0	1.0
NC_015426_2	2.10\|76426\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76426-76462	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76426-76462	0	1.0
NC_015426_2	2.11\|76492\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76492-76528	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76492-76528	0	1.0
NC_015426_2	2.12\|76558\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76558-76594	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76558-76594	0	1.0
NC_015426_2	2.13\|76624\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76624-76660	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76624-76660	0	1.0
NC_015426_2	2.14\|76690\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76690-76726	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76690-76726	0	1.0
NC_015426_2	2.15\|76756\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76756-76791	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76756-76791	0	1.0
NC_015426_2	2.16\|76821\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76821-76856	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76821-76856	0	1.0
NC_015426_2	2.17\|76886\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76886-76922	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76886-76922	0	1.0
NC_015426_2	2.18\|76952\|40\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76952-76991	40	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	76952-76991	0	1.0
NC_015426_2	2.19\|77021\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77021-77056	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77021-77056	0	1.0
NC_015426_2	2.20\|77086\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77086-77121	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77086-77121	0	1.0
NC_015426_2	2.21\|77151\|38\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77151-77188	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77151-77188	0	1.0
NC_015426_2	2.22\|77218\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77218-77253	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77218-77253	0	1.0
NC_015426_2	2.23\|77283\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77283-77319	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77283-77319	0	1.0
NC_015426_2	2.24\|77349\|35\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77349-77383	35	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77349-77383	0	1.0
NC_015426_2	2.25\|77413\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77413-77448	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77413-77448	0	1.0
NC_015426_2	2.26\|77478\|38\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77478-77515	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77478-77515	0	1.0
NC_015426_2	2.27\|77545\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77545-77581	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77545-77581	0	1.0
NC_015426_2	2.28\|77611\|38\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77611-77648	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	77611-77648	0	1.0
NC_015426_3	3.1\|80659\|37\|NC_015426\|CRISPRCasFinder,CRT	80659-80695	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	80659-80695	0	1.0
NC_015426_3	3.2\|80725\|36\|NC_015426\|CRISPRCasFinder,CRT,PILER-CR	80725-80760	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	80725-80760	0	1.0
NC_015426_3	3.3\|80790\|38\|NC_015426\|CRISPRCasFinder,CRT,PILER-CR	80790-80827	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	80790-80827	0	1.0
NC_015426_3	3.4\|80857\|38\|NC_015426\|CRISPRCasFinder,CRT,PILER-CR	80857-80894	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	80857-80894	0	1.0
NC_015426_3	3.5\|80924\|39\|NC_015426\|CRISPRCasFinder,CRT,PILER-CR	80924-80962	39	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	80924-80962	0	1.0
NC_015426_4	4.1\|82582\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	82582-82618	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	82582-82618	0	1.0
NC_015426_4	4.2\|82648\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	82648-82683	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	82648-82683	0	1.0
NC_015426_4	4.3\|82713\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	82713-82748	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	82713-82748	0	1.0
NC_015426_4	4.4\|82778\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	82778-82813	36	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	82778-82813	0	1.0
NC_015426_4	4.5\|82843\|40\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	82843-82882	40	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	82843-82882	0	1.0
NC_015426_4	4.6\|82912\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	82912-82948	37	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	82912-82948	0	1.0
NC_015426_4	4.7\|82978\|38\|NC_015426\|CRISPRCasFinder,CRT	82978-83015	38	NC_015426	Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence	82978-83015	0	1.0
NC_015426_2	2.16\|76821\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76821-76856	36	NC_015427	Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence	24866-24901	3	0.917
NC_015426_2	2.13\|76624\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	76624-76660	37	NC_019777	Cyanobacterium aponinum PCC 10605 plasmid pCYAN10605.01, complete sequence	9811-9847	9	0.757
NC_015426_2	2.23\|77283\|37\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77283-77319	37	CP054565	Escherichia coli strain SCU-478 isolate rectal swab from healthy college student plasmid pSCU-478-1, complete sequence	37926-37962	9	0.757
NC_015426_1	1.4\|74561\|36\|NC_015426\|PILER-CR,CRT	74561-74596	36	NC_013379	Staphylococcus epidermidis plasmid SAP106A, complete sequence	33728-33763	10	0.722
NC_015426_1	1.4\|74561\|36\|NC_015426\|PILER-CR,CRT	74561-74596	36	NC_013944	Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK1, complete sequence	28020-28055	10	0.722
NC_015426_1	1.4\|74561\|36\|NC_015426\|PILER-CR,CRT	74561-74596	36	NC_013945	Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK3, complete sequence	28020-28055	10	0.722
NC_015426_2	2.20\|77086\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77086-77121	36	NC_017041	Rickettsia australis str. Cutlack Plasmid01, complete sequence	11044-11079	10	0.722
NC_015426_2	2.20\|77086\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77086-77121	36	KF751797	Campylobacter phage CJIE4-5, complete genome	9398-9433	10	0.722
NC_015426_2	2.20\|77086\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77086-77121	36	KF751794	Campylobacter phage CJIE4-2, complete genome	7508-7543	10	0.722
NC_015426_2	2.20\|77086\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77086-77121	36	KF751795	Campylobacter phage CJIE4-3, complete genome	7475-7510	10	0.722
NC_015426_2	2.20\|77086\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77086-77121	36	KF751796	Campylobacter phage CJIE4-4, complete genome	7513-7548	10	0.722
NC_015426_2	2.20\|77086\|36\|NC_015426\|PILER-CR,CRISPRCasFinder,CRT	77086-77121	36	KF751793	Campylobacter phage CJIE4-1, complete genome	8952-8987	10	0.722

1. spacer 1.1|74365|34|NC_015426|PILER-CR,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttcaaactttttgcctatagcatctagcttttg	CRISPR spacer
tttcaaactttttgcctatagcatctagcttttg	Protospacer
**********************************

2. spacer 1.2|74429|36|NC_015426|PILER-CR,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tcataaaggtgaaattttagacctaatggaaatggc	CRISPR spacer
tcataaaggtgaaattttagacctaatggaaatggc	Protospacer
************************************

3. spacer 1.3|74495|36|NC_015426|PILER-CR,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tccgcttccgttttcaccgaaaatatttgttatcgg	CRISPR spacer
tccgcttccgttttcaccgaaaatatttgttatcgg	Protospacer
************************************

4. spacer 1.4|74561|36|NC_015426|PILER-CR,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

taaagcaagagtggttgaactaattaaacaaggctt	CRISPR spacer
taaagcaagagtggttgaactaattaaacaaggctt	Protospacer
************************************

5. spacer 1.5|74627|35|NC_015426|PILER-CR,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ggcaaaaagataaccgaggtggaaaataaagctga	CRISPR spacer
ggcaaaaagataaccgaggtggaaaataaagctga	Protospacer
***********************************

6. spacer 2.1|75832|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ttctttaattgataaatgtaacaatttcatttctgg	CRISPR spacer
ttctttaattgataaatgtaacaatttcatttctgg	Protospacer
************************************

7. spacer 2.2|75897|38|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tcagcttgatacagagcctctaagttatttcaatagtc	CRISPR spacer
tcagcttgatacagagcctctaagttatttcaatagtc	Protospacer
**************************************

8. spacer 2.3|75964|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tgagggcttttttgatctttaaaacagtttctatacc	CRISPR spacer
tgagggcttttttgatctttaaaacagtttctatacc	Protospacer
*************************************

9. spacer 2.4|76030|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttgaagcttatcacctataagtttgtatttttttc	CRISPR spacer
tttgaagcttatcacctataagtttgtatttttttc	Protospacer
************************************

10. spacer 2.5|76095|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

atgcagttttaaagtctttattattagctagtgttgc	CRISPR spacer
atgcagttttaaagtctttattattagctagtgttgc	Protospacer
*************************************

11. spacer 2.6|76161|38|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ccgcattgaataattttttagttaaacatttaaattta	CRISPR spacer
ccgcattgaataattttttagttaaacatttaaattta	Protospacer
**************************************

12. spacer 2.7|76228|38|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ggattatagtagtagatagaaaattagatttaaaaaga	CRISPR spacer
ggattatagtagtagatagaaaattagatttaaaaaga	Protospacer
**************************************

13. spacer 2.8|76295|38|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gcaatgggtatgcgactaggtggagctggacatcaagt	CRISPR spacer
gcaatgggtatgcgactaggtggagctggacatcaagt	Protospacer
**************************************

14. spacer 2.9|76362|35|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

atagtttaaaaatgttgttcttcctctgttaaata	CRISPR spacer
atagtttaaaaatgttgttcttcctctgttaaata	Protospacer
***********************************

15. spacer 2.10|76426|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gtgatttagctgctacaaatccaaatgctatttcaac	CRISPR spacer
gtgatttagctgctacaaatccaaatgctatttcaac	Protospacer
*************************************

16. spacer 2.11|76492|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ttcaaggaagtggtattggtctgaatactctatcttt	CRISPR spacer
ttcaaggaagtggtattggtctgaatactctatcttt	Protospacer
*************************************

17. spacer 2.12|76558|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

cagattacttggaacaaataaagtcaatagtctctgg	CRISPR spacer
cagattacttggaacaaataaagtcaatagtctctgg	Protospacer
*************************************

18. spacer 2.13|76624|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

taatttcttttgcttcatcttttttactttcgtaggc	CRISPR spacer
taatttcttttgcttcatcttttttactttcgtaggc	Protospacer
*************************************

19. spacer 2.14|76690|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ctatatatttttgactaccttccgatttagttccata	CRISPR spacer
ctatatatttttgactaccttccgatttagttccata	Protospacer
*************************************

20. spacer 2.15|76756|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

acaaaaaaataacacatccgtatcaatcgattagtt	CRISPR spacer
acaaaaaaataacacatccgtatcaatcgattagtt	Protospacer
************************************

21. spacer 2.16|76821|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gcaagatgatagctggtatggctaaagattatttca	CRISPR spacer
gcaagatgatagctggtatggctaaagattatttca	Protospacer
************************************

22. spacer 2.17|76886|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gtgcaagacgtgtcatgttataagtctttccttgacc	CRISPR spacer
gtgcaagacgtgtcatgttataagtctttccttgacc	Protospacer
*************************************

23. spacer 2.18|76952|40|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

caatactgaactatcctaagagtgatattcgctcaattgg	CRISPR spacer
caatactgaactatcctaagagtgatattcgctcaattgg	Protospacer
****************************************

24. spacer 2.19|77021|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

agattataatagagtgacacaaaattaaaacaatgt	CRISPR spacer
agattataatagagtgacacaaaattaaaacaatgt	Protospacer
************************************

25. spacer 2.20|77086|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gttaaaagattgcttaattttagaagattgctgaaa	CRISPR spacer
gttaaaagattgcttaattttagaagattgctgaaa	Protospacer
************************************

26. spacer 2.21|77151|38|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

caagcaaccatgagtttgattgagcatggtaatttaag	CRISPR spacer
caagcaaccatgagtttgattgagcatggtaatttaag	Protospacer
**************************************

27. spacer 2.22|77218|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

caacatatattcaccacttacaagttttctcatata	CRISPR spacer
caacatatattcaccacttacaagttttctcatata	Protospacer
************************************

28. spacer 2.23|77283|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ggttttattttgaagatgaatttaatactctttttaa	CRISPR spacer
ggttttattttgaagatgaatttaatactctttttaa	Protospacer
*************************************

29. spacer 2.24|77349|35|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

attcagacgtgagtataaattagcagctgccaaca	CRISPR spacer
attcagacgtgagtataaattagcagctgccaaca	Protospacer
***********************************

30. spacer 2.25|77413|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

agatgaaagagtttatttatctaagcaatatggaaa	CRISPR spacer
agatgaaagagtttatttatctaagcaatatggaaa	Protospacer
************************************

31. spacer 2.26|77478|38|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

caagcacgttagtatatgcatagatggaaaatctgaag	CRISPR spacer
caagcacgttagtatatgcatagatggaaaatctgaag	Protospacer
**************************************

32. spacer 2.27|77545|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ggaaaaaaataaaaatatataaacttcaagtacctaa	CRISPR spacer
ggaaaaaaataaaaatatataaacttcaagtacctaa	Protospacer
*************************************

33. spacer 2.28|77611|38|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

atagaaggaataagcattttagaaaatgcagttaaatt	CRISPR spacer
atagaaggaataagcattttagaaaatgcagttaaatt	Protospacer
**************************************

34. spacer 3.1|80659|37|NC_015426|CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

catatccaagagtacgaactcctacacaatctagata	CRISPR spacer
catatccaagagtacgaactcctacacaatctagata	Protospacer
*************************************

35. spacer 3.2|80725|36|NC_015426|CRISPRCasFinder,CRT,PILER-CR matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttcatgggaaatagcgaattagccatttcccaata	CRISPR spacer
tttcatgggaaatagcgaattagccatttcccaata	Protospacer
************************************

36. spacer 3.3|80790|38|NC_015426|CRISPRCasFinder,CRT,PILER-CR matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gaaatatattatatagatgtagaattattgtgtccgtg	CRISPR spacer
gaaatatattatatagatgtagaattattgtgtccgtg	Protospacer
**************************************

37. spacer 3.4|80857|38|NC_015426|CRISPRCasFinder,CRT,PILER-CR matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

atatatagaataatattatccagataggagcaatgtca	CRISPR spacer
atatatagaataatattatccagataggagcaatgtca	Protospacer
**************************************

38. spacer 3.5|80924|39|NC_015426|CRISPRCasFinder,CRT,PILER-CR matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

atgcattaatgggaattatagaattagaagataagtaag	CRISPR spacer
atgcattaatgggaattatagaattagaagataagtaag	Protospacer
***************************************

39. spacer 4.1|82582|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gtttaaatttaataaaaattctggttgtgtaaaggta	CRISPR spacer
gtttaaatttaataaaaattctggttgtgtaaaggta	Protospacer
*************************************

40. spacer 4.2|82648|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

taaaacagttggaatgacaatcgttacttccgctat	CRISPR spacer
taaaacagttggaatgacaatcgttacttccgctat	Protospacer
************************************

41. spacer 4.3|82713|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

gctcagggtcaactcagcaagttgctagaaggtgca	CRISPR spacer
gctcagggtcaactcagcaagttgctagaaggtgca	Protospacer
************************************

42. spacer 4.4|82778|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

aattacttttaataataacggtgatataaaagacag	CRISPR spacer
aattacttttaataataacggtgatataaaagacag	Protospacer
************************************

43. spacer 4.5|82843|40|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

ctaaccattctggtcccaaatctaacattgatttagatac	CRISPR spacer
ctaaccattctggtcccaaatctaacattgatttagatac	Protospacer
****************************************

44. spacer 4.6|82912|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

caaaattattatcacctatttctataacaccttctga	CRISPR spacer
caaaattattatcacctatttctataacaccttctga	Protospacer
*************************************

45. spacer 4.7|82978|38|NC_015426|CRISPRCasFinder,CRT matches to NC_015426 (Clostridium botulinum BKT015925 plasmid p2BKT015925, complete sequence) position: , mismatch: 0, identity: 1.0

tttattaccacttaatgctattcttactttatctccaa	CRISPR spacer
tttattaccacttaatgctattcttactttatctccaa	Protospacer
**************************************

46. spacer 2.16|76821|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_015427 (Clostridium botulinum BKT015925 plasmid p4BKT015925, complete sequence) position: , mismatch: 3, identity: 0.917

gcaagatgatagctggtatggctaaagattatttca	CRISPR spacer
gtaaaatgatagttggtatggctaaagattatttca	Protospacer
*.**.*******.***********************

47. spacer 2.13|76624|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_019777 (Cyanobacterium aponinum PCC 10605 plasmid pCYAN10605.01, complete sequence) position: , mismatch: 9, identity: 0.757

taatttcttttgcttcatcttttttactttcgtaggc	CRISPR spacer
taatttctttttcttcatctgttttaccgttatatct	Protospacer
*********** ******** ******. *..**  .

48. spacer 2.23|77283|37|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to CP054565 (Escherichia coli strain SCU-478 isolate rectal swab from healthy college student plasmid pSCU-478-1, complete sequence) position: , mismatch: 9, identity: 0.757

ggttttattttgaagatgaatttaatactctttttaa	CRISPR spacer
gtttttattttgaagatgaatttgttaccaatataat	Protospacer
* *********************. ***.  * * *

49. spacer 1.4|74561|36|NC_015426|PILER-CR,CRT matches to NC_013379 (Staphylococcus epidermidis plasmid SAP106A, complete sequence) position: , mismatch: 10, identity: 0.722

taaagcaagagtggttgaactaattaaacaaggctt	CRISPR spacer
ttattatcgagtggttgaattacttaaacaaggcaa	Protospacer
* *     ***********.** ***********

50. spacer 1.4|74561|36|NC_015426|PILER-CR,CRT matches to NC_013944 (Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK1, complete sequence) position: , mismatch: 10, identity: 0.722

taaagcaagagtggttgaactaattaaacaaggctt	CRISPR spacer
ttattatcgagtggttgaattacttaaacaaggcaa	Protospacer
* *     ***********.** ***********

51. spacer 1.4|74561|36|NC_015426|PILER-CR,CRT matches to NC_013945 (Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK3, complete sequence) position: , mismatch: 10, identity: 0.722

taaagcaagagtggttgaactaattaaacaaggctt	CRISPR spacer
ttattatcgagtggttgaattacttaaacaaggcaa	Protospacer
* *     ***********.** ***********

52. spacer 2.20|77086|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to NC_017041 (Rickettsia australis str. Cutlack Plasmid01, complete sequence) position: , mismatch: 10, identity: 0.722

gttaaaagattgcttaattttagaagattgctgaaa	CRISPR spacer
aatagcagatggcttaattttagaatattgcttttc	Protospacer
. **. **** ************** ******

53. spacer 2.20|77086|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to KF751797 (Campylobacter phage CJIE4-5, complete genome) position: , mismatch: 10, identity: 0.722

gttaaaagattgcttaattttagaagattgctgaaa	CRISPR spacer
cttaaaagatggcttaatttaagaagaaataaataa	Protospacer
 ********* ********* ******     . **

54. spacer 2.20|77086|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to KF751794 (Campylobacter phage CJIE4-2, complete genome) position: , mismatch: 10, identity: 0.722

gttaaaagattgcttaattttagaagattgctgaaa	CRISPR spacer
cttaaaagatggcttaatttaagaagaaataaataa	Protospacer
 ********* ********* ******     . **

55. spacer 2.20|77086|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to KF751795 (Campylobacter phage CJIE4-3, complete genome) position: , mismatch: 10, identity: 0.722

gttaaaagattgcttaattttagaagattgctgaaa	CRISPR spacer
cttaaaagatggcttaatttaagaagaaataaataa	Protospacer
 ********* ********* ******     . **

56. spacer 2.20|77086|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to KF751796 (Campylobacter phage CJIE4-4, complete genome) position: , mismatch: 10, identity: 0.722

gttaaaagattgcttaattttagaagattgctgaaa	CRISPR spacer
cttaaaagatggcttaatttaagaagaaataaataa	Protospacer
 ********* ********* ******     . **

57. spacer 2.20|77086|36|NC_015426|PILER-CR,CRISPRCasFinder,CRT matches to KF751793 (Campylobacter phage CJIE4-1, complete genome) position: , mismatch: 10, identity: 0.722

gttaaaagattgcttaattttagaagattgctgaaa	CRISPR spacer
cttaaaagatggcttaatttaagaagaaataaataa	Protospacer
 ********* ********* ******     . **

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

22434 : 56725

Lactococcus_phage(30.0%)

protease,transposase,integrase

attL 19441:19456|attR 34001:34016

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
19441:19456	attL	NA	NA	NA	NA
WP_013726729.1\|22434_23253_+\|integrase	tyrosine-type recombinase/integrase	A0A2R2ZGL2	Clostridioides_phage	6.0e-09	26.4
WP_013726730.1\|23399_23801_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_019278524.1\|23825_24044_-	hypothetical protein	NA	NA	NA	NA
WP_013726732.1\|24284_25454_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_013726733.1\|25493_26510_-	phosphatidylinositol-specific phospholipase C	NA	NA	NA	NA
WP_013726734.1\|26925_27729_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_013726735.1\|27865_29125_-	MBL fold metallo-hydrolase	Q332B9	Clostridium_botulinum_C_phage	4.2e-147	63.3
WP_013726737.1\|29523_30834_+	aerolysin family beta-barrel pore-forming toxin	NA	NA	NA	NA
WP_013726738.1\|31496_33083_+	clostripain	NA	NA	NA	NA
WP_019278526.1\|33202_33583_-	hypothetical protein	NA	NA	NA	NA
WP_019278527.1\|33892_34285_+	DUF805 domain-containing protein	NA	NA	NA	NA
34001:34016	attR	NA	NA	NA	NA
WP_013726742.1\|34860_35376_-	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
WP_013726743.1\|35543_35963_-	hypothetical protein	NA	NA	NA	NA
WP_013726744.1\|36081_37377_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.2e-43	31.7
WP_013725097.1\|37369_38122_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.3e-55	45.5
WP_013726745.1\|38347_39511_-	WG repeat-containing protein	NA	NA	NA	NA
WP_013726746.1\|40118_41312_-	membrane protein	NA	NA	NA	NA
WP_013726747.1\|41532_42177_-	peptidase	NA	NA	NA	NA
WP_013726748.1\|42264_43128_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	E9P639	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-21	29.5
WP_013726749.1\|43310_44282_-	hypothetical protein	NA	NA	NA	NA
WP_019278568.1\|44420_44633_-	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	1.9e-23	79.4
WP_013726750.1\|44629_44947_-	hypothetical protein	NA	NA	NA	NA
WP_013726751.1\|45110_45785_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	D2XQ03	Bacillus_virus	6.7e-59	42.9
WP_013726752.1\|45911_46052_+	ribbon-helix-helix domain-containing protein	NA	NA	NA	NA
WP_013726753.1\|46409_46733_-	hypothetical protein	NA	NA	NA	NA
WP_013726754.1\|46729_46939_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_019278569.1\|47142_47538_-	DUF3887 domain-containing protein	NA	NA	NA	NA
WP_013726756.1\|47515_48277_-\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_019278570.1\|48329_49634_-	GHKL domain-containing protein	X5JAC0	Clostridium_phage	2.7e-19	26.4
WP_013726758.1\|49659_50361_-	response regulator transcription factor	NA	NA	NA	NA
WP_013726759.1\|50611_51505_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	A0A1B2LRR6	Wolbachia_phage	5.0e-17	34.0
WP_013726760.1\|51953_52901_-	hypothetical protein	NA	NA	NA	NA
WP_013726762.1\|53633_54929_-\|transposase	IS21-like element ISCbo2 family transposase	A0A059NT83	Lactococcus_phage	1.5e-43	32.2
WP_013726763.1\|55068_55515_-	hypothetical protein	NA	NA	NA	NA
WP_013726764.1\|55702_56725_+\|transposase	IS6 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NC_015427

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7804 : 39381

Clostridium_phage(57.14%)

head,terminase,plate,protease,capsid,portal,tail,integrase

attL 31376:31392|attR 33110:33126

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013726813.1\|7804_8794_+	hypothetical protein	Q0SPG9	Clostridium_phage	1.5e-06	45.2
WP_013726814.1\|8820_9003_+	hypothetical protein	NA	NA	NA	NA
WP_013726815.1\|9152_9446_+	hypothetical protein	NA	NA	NA	NA
WP_013726816.1\|9503_9797_+	hypothetical protein	A0A0H3UZB6	Geobacillus_virus	3.2e-05	35.6
WP_013726817.1\|9838_10219_+	hypothetical protein	NA	NA	NA	NA
WP_013726818.1\|10239_10617_+	hypothetical protein	NA	NA	NA	NA
WP_013726819.1\|10714_11866_-	cell wall-binding protein	Q332B8	Clostridium_botulinum_C_phage	4.5e-55	66.7
WP_013726820.1\|11909_12170_-	hypothetical protein	NA	NA	NA	NA
WP_013726821.1\|12235_13918_-	endopeptidase	A0A0A7RUI9	Clostridium_phage	1.1e-94	52.8
WP_080008842.1\|13988_14582_-	SGNH/GDSL hydrolase family protein	A0A0U4JWX9	Bacillus_phage	3.8e-58	57.1
WP_013726823.1\|14683_16111_-\|plate	BppU family phage baseplate upper protein	A0A0A7S181	Clostridium_phage	9.0e-29	48.9
WP_029169516.1\|16110_16809_-\|tail	phage tail component	A0A0A7RWN1	Clostridium_phage	3.0e-46	44.3
WP_013726825.1\|16810_22105_-\|tail	phage tail tape measure protein	A0A0A7RVT5	Clostridium_phage	7.7e-41	32.3
WP_158002118.1\|22160_22313_-	hypothetical protein	E2ELJ3	Clostridium_phage	4.2e-09	54.0
WP_013726828.1\|22680_23259_-\|tail	tail protein	E2ELJ1	Clostridium_phage	3.3e-46	47.9
WP_013726829.1\|23264_23600_-	hypothetical protein	A0A0K2CZA4	Paenibacillus_phage	2.3e-12	39.6
WP_013726830.1\|23688_24072_-	HK97 gp10 family phage protein	E2ELI9	Clostridium_phage	7.5e-31	49.3
WP_013726831.1\|24064_24427_-\|head	phage head closure protein	A0A0K2CZB5	Paenibacillus_phage	9.3e-07	41.9
WP_013726832.1\|24686_25832_-\|capsid	phage major capsid protein	E2ELI5	Clostridium_phage	1.5e-119	57.5
WP_013726833.1\|25833_26610_-\|protease	Clp protease ClpP	Q8W605	Listeria_phage	8.4e-37	40.3
WP_013726834.1\|26610_27720_-\|portal	phage portal protein	E2ELI3	Clostridium_phage	2.6e-84	42.1
WP_029169556.1\|27764_29411_-\|terminase	terminase	E2ELI2	Clostridium_phage	3.5e-149	48.5
WP_029169555.1\|29394_29886_-	hypothetical protein	E2ELI1	Clostridium_phage	6.0e-33	45.2
WP_141640261.1\|30069_30339_-	HNH endonuclease	A0A1S7FZ53	Listeria_phage	2.7e-19	52.8
WP_013726837.1\|30322_30946_-	hypothetical protein	NA	NA	NA	NA
WP_013726838.1\|30986_31289_-	hypothetical protein	NA	NA	NA	NA
WP_013726839.1\|31301_31448_-	hypothetical protein	NA	NA	NA	NA
31376:31392	attL	NA	NA	NA	NA
WP_013726840.1\|31504_31660_-	hypothetical protein	NA	NA	NA	NA
WP_013726841.1\|31987_32533_-\|integrase	site-specific integrase	E2ELN7	Clostridium_phage	3.2e-59	62.4
WP_013726842.1\|32765_33188_-	hypothetical protein	A0A0A7RTL7	Clostridium_phage	2.6e-32	52.8
33110:33126	attR	NA	NA	NA	NA
WP_013726843.1\|33160_33313_-	hypothetical protein	NA	NA	NA	NA
WP_029169553.1\|33481_33751_-	DUF1599 domain-containing protein	A0A2H4J4N1	uncultured_Caudovirales_phage	1.8e-18	52.3
WP_013726846.1\|34028_34493_-	hypothetical protein	Q24LD4	Clostridium_phage	4.7e-35	62.4
WP_013726847.1\|34516_34846_-	phosphoadenosine phosphosulfate reductase family protein	Q24LD4	Clostridium_phage	2.9e-07	43.0
WP_013726848.1\|34863_35241_-	hypothetical protein	L0LC12	Bacillus_phage	3.2e-10	38.0
WP_013726849.1\|35269_35593_-	hypothetical protein	NA	NA	NA	NA
WP_013726850.1\|35633_35822_-	hypothetical protein	NA	NA	NA	NA
WP_043920885.1\|35834_36038_-	hypothetical protein	NA	NA	NA	NA
WP_013726852.1\|36064_36244_-	hypothetical protein	NA	NA	NA	NA
WP_013726853.1\|36266_37043_-	hypothetical protein	NA	NA	NA	NA
WP_013726854.1\|37110_37266_-	hypothetical protein	NA	NA	NA	NA
WP_013726855.1\|37283_37763_-	hypothetical protein	A0A0A7AQW7	Bacillus_phage	4.5e-25	40.1
WP_013726856.1\|37899_38625_-	DnaD domain protein	A0A2H4JC54	uncultured_Caudovirales_phage	8.4e-23	35.7
WP_013726857.1\|38637_39381_-	hypothetical protein	S5MP04	Brevibacillus_phage	2.0e-32	36.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NC_015425

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015425_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015425_1

162095-162202

Unclear

Consensus_repeat	Method
ACCCGAAGGTCGTAGGTTCAAGTCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015425_1

>merge|NC_015425|1|162095-162202|CRISPRCasFinder
ACCCGAAGGTCGTAGGTTCAAGTCCTGTCCCCGCAACCATACATGGCGGAATAGCTCAGCTGGCTAGAGCATTCGGTTCATACCCGAAGTGTCGTAGGTTCAAGTCCT

>NC_015425|1|1|162095-162202|CRISPRCasFinder
ACCCGAAGGTCGTAGGTTCAAGTCCT	GTCCCCGCAACCATACATGGCGGAATAGCTCAGCTGGCTAGAGCATTCGGTTCATA
CCCGAAGTGTCGTAGGTTCAAGTCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015425.1\|WP_013724395.1\|167029_167569_+\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223707
NC_015425.1\|WP_162836943.1\|174654_176142_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NC_015425.1\|WP_029169678.1\|169761_170148_+\|thioesterase-family-protein	unknown	unknown	gnl\|CDD\|227783
NC_015425.1\|WP_019278274.1\|163127_165521_+\|stage-II-sporulation-protein-E	unknown	unknown	gnl\|CDD\|274328
NC_015425.1\|WP_013724398.1\|170249_171920_+\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|376511
NC_015425.1\|WP_013724383.1\|154320_155367_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|234605
NC_015425.1\|WP_013724390.1\|161065_161338_+\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|368217
NC_015425.1\|WP_019278273.1\|160590_160986_+\|spore-cortex-biosynthesis-protein-YabQ	unknown	unknown	gnl\|CDD\|131939
NC_015425.1\|WP_019278276.1\|174081_174561_+\|transcription-elongation-factor-GreA	unknown	unknown	gnl\|CDD\|234693
NC_015425.1\|WP_013724385.1\|156464_157991_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NC_015425.1\|WP_013724387.1\|159577_159856_+\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|259853
NC_015425.1\|WP_013724396.1\|167632_169621_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
NC_015425.1\|WP_013724394.1\|165621_167025_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NC_015425.1\|WP_029169532.1\|159930_160200_+\|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl\|CDD\|224109
NC_015425.1\|WP_029169507.1\|172044_172824_+\|type-III-pantothenate-kinase	unknown	unknown	gnl\|CDD\|237347
NC_015425.1\|WP_013724400.1\|172842_173805_+\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NC_015425.1\|WP_013724389.1\|160295_160586_+\|sporulation-protein-YabP	unknown	unknown	gnl\|CDD\|274341
NC_015425.1\|WP_013724384.1\|155817_156369_+\|stage-V-sporulation-protein-T	unknown	unknown	gnl\|CDD\|131898
NC_015425.1\|WP_013724386.1\|158023_159469_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|226465
NC_015425.1\|WP_013724391.1\|161394_161805_+\|RNA-binding-protein-S1	unknown	unknown	gnl\|CDD\|235614

Protein	Function_ID	Function_description	E-value
NC_015425.1\|WP_013724395.1\|167029_167569_+\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	3.2392e-91
NC_015425.1\|WP_162836943.1\|174654_176142_+\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NC_015425.1\|WP_029169678.1\|169761_170148_+\|thioesterase-family-protein	gnl\|CDD\|227783	COG5496, COG5496, Predicted thioesterase [General function prediction only].	2.38384e-30
NC_015425.1\|WP_019278274.1\|163127_165521_+\|stage-II-sporulation-protein-E	gnl\|CDD\|274328	TIGR02865, Stage_II_sporulation_protein_E, stage II sporulation protein E. Stage II sporulation protein E (SpoIIE) is a multiple membrane spanning protein with two separable functions. It plays a role in the switch to polar cell division during sporulation. By means of it protein phosphatase activity, located in the C-terminal region, it activates sigma-F. All proteins that score above the trusted cutoff to this model are found in endospore-forming Gram-positive bacteria. Surprisingly, a sequence from the Cyanobacterium-like (and presumably non-spore-forming) photosynthesizer Heliobacillus mobilis is homologous, and scores between the trusted and noise cutoffs. [Cellular processes, Sporulation and germination].	0
NC_015425.1\|WP_013724398.1\|170249_171920_+\|formate--tetrahydrofolate-ligase	gnl\|CDD\|376511	pfam01268, FTHFS, Formate--tetrahydrofolate ligase.	0
NC_015425.1\|WP_013724383.1\|154320_155367_+\|peptidylprolyl-isomerase	gnl\|CDD\|234605	PRK00059, prsA, peptidylprolyl isomerase; Provisional.	5.71669e-114
NC_015425.1\|WP_013724390.1\|161065_161338_+\|dihydroorotate-dehydrogenase	gnl\|CDD\|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	0.00111643
NC_015425.1\|WP_019278273.1\|160590_160986_+\|spore-cortex-biosynthesis-protein-YabQ	gnl\|CDD\|131939	TIGR02893, Spore_protein_YabQ, spore cortex biosynthesis protein YabQ. YabQ, a protein predicted to span the membrane several times, is found in exactly those genomes whose species perform sporulation in the style of Bacillus subtilis, Clostridium tetani, and others of the Firmicutes. Mutation of this sigma(E)-dependent gene blocks development of the spore cortex. The length of the C-terminal region, including some hydrophobic regions, is rather variable between members. [Cellular processes, Sporulation and germination].	2.90631e-17
NC_015425.1\|WP_019278276.1\|174081_174561_+\|transcription-elongation-factor-GreA	gnl\|CDD\|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	3.10773e-77
NC_015425.1\|WP_013724385.1\|156464_157991_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.34572e-126
NC_015425.1\|WP_013724387.1\|159577_159856_+\|HU-family-DNA-binding-protein	gnl\|CDD\|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	6.1232e-42
NC_015425.1\|WP_013724396.1\|167632_169621_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_015425.1\|WP_013724394.1\|165621_167025_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	1.31999e-77
NC_015425.1\|WP_029169532.1\|159930_160200_+\|RNA-binding-S4-domain-containing-protein	gnl\|CDD\|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	3.59609e-27
NC_015425.1\|WP_029169507.1\|172044_172824_+\|type-III-pantothenate-kinase	gnl\|CDD\|237347	PRK13318, PRK13318, type III pantothenate kinase.	5.28578e-154
NC_015425.1\|WP_013724400.1\|172842_173805_+\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	8.25507e-138
NC_015425.1\|WP_013724389.1\|160295_160586_+\|sporulation-protein-YabP	gnl\|CDD\|274341	TIGR02892, conserved_hypothetical_protein, sporulation protein YabP. Members of this protein family are the YabP protein of the bacterial sporulation program, as found in Bacillus subtilis, Clostridium tetani, and other spore-forming members of the Firmicutes. In Bacillus subtilis, a yabP single mutant appears to sporulate and germinate normally (), but is in an operon with yabQ (essential for formation of the spore cortex), it near-universal among endospore-forming bacteria, and is found nowhere else. It is likely, therefore, that YabP does have a function in sporulation or germination, one that is either unappreciated or partially redundant with that of another protein. [Cellular processes, Sporulation and germination].	3.5944e-24
NC_015425.1\|WP_013724384.1\|155817_156369_+\|stage-V-sporulation-protein-T	gnl\|CDD\|131898	TIGR02851, stage_V_sporulation_protein_T, stage V sporulation protein T. Members of this protein family are the stage V sporulation protein T (SpoVT), a protein of the sporulation/germination program in Bacillus subtilis and related species. The amino-terminal 50 amino acids are nearly perfectly conserved across all endospore-forming bacteria. SpoVT is a DNA-binding transcriptional regulator related to AbrB (See pfam04014). [Regulatory functions, DNA interactions, Cellular processes, Sporulation and germination].	2.43857e-93
NC_015425.1\|WP_013724386.1\|158023_159469_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|226465	COG3956, COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only].	0
NC_015425.1\|WP_013724391.1\|161394_161805_+\|RNA-binding-protein-S1	gnl\|CDD\|235614	PRK05807, PRK05807, RNA-binding protein S1.	3.3341e-72

>NC_015425.1|WP_013724391.1|161394_161805_+|RNA-binding-protein-S1
MALKLGSILEGTVVNITKFGAFIEVEGKTGLVHISEVADTYVKDIREHIKEQDKVKVKVISVDDSGRLSLSIKQAMPSRKSAKPVEIDWEKEKKKSAPSSVNFEDAISRFLKDSEERFQDIRKHQNIKGNKYSKKS
>NC_015425.1|WP_013724390.1|161065_161338_+|dihydroorotate-dehydrogenase
MKNKNKIKVMILTIIMIYACYILVHQQITIKNKKAQLENCKIELQKVNDQHQKLLDTIKMSETNRYVEQLARERLGFLKQGETVVVHKKD
>NC_015425.1|WP_019278273.1|160590_160986_+|spore-cortex-biosynthesis-protein-YabQ
MLIPIHSQFNLIFYSVLAGVLTGVLFDIYRILRGLENPNKILTFIEDILFWIFTGILVFIFLLYTGHVYVGIYLYLYIALGIYIYMRFISVHFLKIQYKLIRGIFKFLRILKNLFLYFLELMVYNVTRKNK
>NC_015425.1|WP_013724389.1|160295_160586_+|sporulation-protein-YabP
MEVKKESVESKKSNLILENRNKLMITGIVEVVCFDEKIIILDTRLGTLTIKGEGLKVQKLDVQNGEVAISGHINSCVYTTTQSKKDKDSIIARLFR
>NC_015425.1|WP_029169532.1|159930_160200_+|RNA-binding-S4-domain-containing-protein
MRLDKYLKVSRIIKRRTVAKEACESGRVFINGKVAKPSSEINEDDIIEVKFANSSLKAKVINITNHVLKADAKSMYEIIFDNMVAKEEQ
>NC_015425.1|WP_013724387.1|159577_159856_+|HU-family-DNA-binding-protein
MNKAELITSMAEKSQLTKKDAEVALKAFIESVEEALMDGDKVQLVGFGTFETRERAERKGRNPRTKEEITIPAATVPVFKAGKEFKEIVNNK
>NC_015425.1|WP_013724386.1|158023_159469_+|nucleoside-triphosphate-pyrophosphohydrolase
MIKIVGLGPGSKDAITIGTLDILKNSENVYFRTEIHPNVEYLKRLGVDFESYDNKYESSEAFDEVYESIAKDLIEKHKIHGDLVYAVPGHPLVAEKSVNLLLQLCENNRIEAKILPAISFIDAMMESLKLDPVNGVKVIDAFDIKNQILDKRVGTVITQVYNKFIASEVKLALLEYYRDDMDIYFVRAAGVEGLESIRRIHLYELDRQEDIDYLTSIYIPRNLNVATDFQDLLDIMEQLRGENGCPWDKEQDHNSLKRSLIEECYEAIDAIEKEDDENLVEELGDILLQVVFHAQIGKEEGYFNINDIIRSICDKLIKRHPHVFGNLDISDSTDVLKNWDEIKHKEKGFVTYTDELKHISKCLPALIRAEKIQKKAAKVGFDWNNIEPALNKVLEEYEEVKDVYKSHNKEKIIEEVGDLIFSVVNVARFLDIDPENALNYTIDKFISRFYYIENKVKELDKDITEMSLEELDNFWEMSKEK
>NC_015425.1|WP_013724385.1|156464_157991_+|polysaccharide-biosynthesis-protein
MKKQSLIKGTFILGFAGIFARCIGMCFRIPLTILVGDEGLGYYQMAYPLYMLFIAIASGVPLAMSKMISEQNAKSNEKGILEVLKQALLLMIILGMGTSVIILVLSNKLILLFKWDIKAYYSLIALGIAPFFIAIVSVFRGFFQGLQNMTPTAISQILEQIARVVVGIGLAIILLPKGVEYAAGGATLGAAAGGILAGIYLIRKYKRVIKDFKIRRVKFNSIVMDELLKTAIPISLGAAVGTIMNVIDSIMVPQLLLEAGFSSKNAAILYGQLTGKAAVLVNVPLTLSAAICASVVPIISEAYILKNTNKLNKNILSAIKISTVIALPSLCGLYFLSSQVLNLIFRGQAQGAMILKYSSLAIPFIILAQTTTIILQATSSKKMPIINLLIGCIIKMVITSILVPIPNINVYGAIIGTISAYVVAVVLNILLLKKKMNIKIDLTQIFIKPAYASMAMILLVVFVYIKVYNYTMSNSIACLISIFLGMISYGVFMILSGTFDYRKIKSRK
>NC_015425.1|WP_013724384.1|155817_156369_+|stage-V-sporulation-protein-T
MKATGIVRRIDDLGRVVIPKEIRRTLRIREGDPLEIFTDRDGGVILKKYSPIEELSNFSKEYAEALQNTIGNIILICDKDNIISVSGATKKEYMDRKISIELERLMEERNSVLMGEEGEKVIPITDDEETAEEYSSQVIVPIIAEGDAIGAVIIASKEDDGSFGDVEVKLAEAAASFLGKQME
>NC_015425.1|WP_013724383.1|154320_155367_+|peptidylprolyl-isomerase
MKNIRKLVATAVLCVFTMSAVGCSMIEKTPEAIKKTVVAKVGDKKITKGELDSHFGVKRYLDQFKQQYGENFEQNPQVKEQVKQIKIAVAKQIASQEALKQEAEKLKLVPNDQELKKEMDKKIQEFKKEQNIKDDKGLDSALKMSGLQKSDFEKLIKDNIIIEKLQNELTKNIKVDDKEIEKYYNTNKDKYPKDPKNPTKIHVAHIILQAKTPEDDAKAKDEIKSIKEELNKGGDFAVLAKKYSQDGSKDKGGDLGSVPTVNSGFDQDFMNAALTLKDGQISDPVKTQFGYHIIKMIKREEAPCKTLAEVKNQVKEDILQNKKNEVIKNKFKEIQDKANIKIYEDKIA
>NC_015425.1|WP_019278274.1|163127_165521_+|stage-II-sporulation-protein-E
MQYNSEILPYKRVKNVGLEQKEKKQIERLLIFKNLIYFVSAMLVSRVLLLNEDSTTAPFGIALLIASVIQSRKMVIPMSLGCFAGYMSLYDKLTSLPEYLIIIASLMVLSYLLNRKNKIRNISIIFSIISLEILLSEFFIKHLTLNVAFLTMFLQMICIIPLYFILERSLICVKALKSKHLFTSEEIISISMLISLILAGTWGVEIFDVSIRNILALNFILMISYINGSNVGAASGIAIGSIIGISSENILIFMSVYGLCGLIAGIFKESGKVLTSASYVITFLILKLYSNIDVEFKLVEIVIATTIFLIIPGKVYDKINLELDWEKKQDYLNKNYINRIKDMLFQRLYGFSNVLYNISGNLNTLADNDKLVMKNKSSALIENLADRVCSTCQMNSNCWKKETYITYTAFGELIQNHQEGNNKLPQEINRKCIKRTILLNNTKEIVNNYIINEMWRKRLSEGREIIAGQINNMASSLKEVMEEFNSDVKFNSDSEKRIRKIFENKTFKYKDIFCYEDKNNRLNVKLYLKSCGGAQLCSKKILPLINEAVEKNMCISDDGCVIDPKTSICTMTFEEAPKFYVSSYVGRQCKNGEKQNGDSYSFGKISDGSYMCIISDGMGSGPEASEESKVAVELIEKFTRFGISKATAINTVNSIMSLKFSENEKFSTLDLTSVDLYTGDTSFMKVGAVPSFIKSGKNVEVITSNTLPIGVLDKVDLEVTNKKLKNGDIIVMLSDGVLDYDNNNVGKIDWILDYLKNSNINSPKELVDGIISRAKELSGGRAKDDMTAIVCKVYSVY
>NC_015425.1|WP_013724394.1|165621_167025_+|tRNA-lysidine(34)-synthetase-TilS
MGVFNLIEKVIHTIKQNNMFEVKDKVVVAVSGGPDSICLLHILYKLKEELGITLVAAHINHCLRGEEADKDEEYVRKFCENLNIECFVKKEDVHKISKDRGISCEMAGREVRYEFFSEVLNKVGANKIAVAHNANDQAETILMRMLRGTGLEGLVGIRAVRDNIFLRPIIDITRDEIENYCDVNNLNPRIDKTNLENIYTRNKIRLELIPYIQKNFNSDVIEVLNRFSDTVKIDNDYLNKISLEKYNKYCKSEKDKIIMRAEVFNEHEAILTRIIRIALKDLKGNLHNFDKSHVYDIIDIQKKSTGKFIMLPENIRVLNSYADIHLYKNKNKINIYKGKKEYNLVINKENILDNGLKITLDIINNVEDAKFNKSSLIKYFDYDKINRDIKLRYRKNGDKFVPLGMNGTKKLKDLFIDLKIPKENRDTIPLIVFDDEISWIVGYRISDKFKINKKTKRVLKIKIEREA
>NC_015425.1|WP_013724395.1|167029_167569_+|hypoxanthine-phosphoribosyltransferase
MRNDIERVLFSEEELTAKVKEIGKQITEDYKGKDIILVGILKGSVPFMADLMKYIEIPCKIDFMDVSSYGNSTETSGVVRILKDLEFEVEGRDILIVEDIVDTGTTLEYLRTYLKSKNPNSVSVACLLNKPDRRKVEVDVKYLGYEVPDEFLVGYGLDYAEKYRNLPFIGILKESVYKK
>NC_015425.1|WP_013724396.1|167632_169621_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MGGINVKKRLSSVTIWILLLICVFFAALTLLESNKASGTVSYNQFKKYWIDNKVSRVEIKQDGRTVVGELKDKSKTQFQVVVPQTLLMQDILVNNPKPSVDVKFEPASSMPMWISWLPTIILILLMIGFWVMFMQQSQGGGGNRGVMNFGKSRAKLASPDSQKVTFKEVAGADEEKAELEEIVDFLKDPNKYLDMGARIPKGILLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKNSPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGVNEGIILVAATNRPDILDKALLRPGRFDRQILVGAPDAKGREEVLKVHVRNKHLEDNVDLKVLAKRTPGFVGADLENLMNEAALLAVRNNKKKIGMGELEEAITRVIAGPEKKSRVIHEEDRKLTAYHEAGHAIVAKFSRYSDPVHEISIIPRGMAGGYTMQLPERDKSYASKSKLKDDMVGLLGGRVAEQLILGDISTGASNDIQRVSNVARKMVMEYGMSEKLGTITFGSDHDEVFIGRDIGKSKNYSEEVAFEIDNEVKALVNEAYKKAEKILTEHVDKLHAVAKRLLEKEKISGEEFNAIVEDRPFNEQKENAIDLEKHDDVEEVKELEKDRVSEEEKNESIDAFAKDLNLEEKKEI
>NC_015425.1|WP_029169678.1|169761_170148_+|thioesterase-family-protein
MEFNVHEGTKGLMEMVVEEQHSAKKVGSGLVDVFSTPSMIALMENTSQASVKDSLPEGYATVGIEISVKHMKATPIGMKVRCETILKKVDRKKLVFEVEAYDEAGKIGEGTHTRYIVNSEEFVKNIQK
>NC_015425.1|WP_013724398.1|170249_171920_+|formate--tetrahydrofolate-ligase
MKSDIEIAQGANMKKITDIAKNLGLEEDDIELYGNYKCKISLDVLKNRQNKEDGKLILVTAINPTPAGEGKSTITVGLGQALCKLNKKAVIALREPSLGPVFGIKGGAAGGGYSQVVPMEDINLHFTGDMHAITSANNLLAAAIDNHIHQGNNLKIDSRRIVFKRVMDMNDRALRNIVVGMGGKVNGFLREDGFTITVASEIMAILCLSNNLMDLKQKFGEILVAYNINGEPVYCKDLKVQGAMAMLMKDAIKPNLVQTLENTPAIIHGGPFANIAHGCNSILATKMAMKLGEFAITEAGFGADLGGEKFLDIKCRKGNIKPDCIVLVATIRALKHHGGVDKDKLSIPNIDALKEGIGNLKKQIENMKKYGVPVVVAINKFITDSDEEIKCIKEFCKNEDVKVSLAEVWEKGGDGGINLAQKVVKVLEEDKGDFKYLYDEKLSIKEKISVIAKEIYGASEVQYDKKVEKEIKDIEDIGLDKVPICVAKTQYSLSDDPSLLGNPKNFKINVKEVRLSNGAGFIVVLTGNIMTMPGLPKIPAANRMDILEDGTIQGLF
>NC_015425.1|WP_029169507.1|172044_172824_+|type-III-pantothenate-kinase
MLFVLDAGNTNIVLGIYKGEELVLECRLGTDAKRTADEYGIQVLELLSHNNIDPKDIEGVIISSVVPNIMYSIEHMIRKYFNVEPIVVGPGVKTGINIKYDNPKSVGADRIVNAVAAHELFKKPLIIIDFGTATTYCAVTKKGDYLGGAICPGIKISAAALFEKAAKLPRIELIKPSHVICKNTVTSMQAGIVYGYIGQVDYIVSKIKQEMIELGEGEPYVIATGGFATLISEDSTTIDKVCPFLTLEGLKIIYEKNKE
>NC_015425.1|WP_013724400.1|172842_173805_+|tRNA-dihydrouridine-synthase-DusB
MKIGNLNFENNVFLAPMAGVTDIAYRGLCKEMGCGLVYTEMISAKGMYYNNENTKKLLMLSKEEKPVAAQIFGSDPLVMARACEILNEDNGVCIIDINMGCPAPKIVKNGEGSALMKTPELAAEIVLEMKKISKKPVTVKFRKGFDNDNINAIEFAKRMEQAGADAIAIHGRTRAQMYEGKADWDIIRRVKESVNIPVIGNGDVFSAEKAFQLREETNCDGIMIARGAMGNPWIFKQIQLALNNEEVIYPTSEEKIDMCIRHLNLAIQYHGELKAVREMRKHIAWYIKGIKNCTDIKNKINVEKESHNVIKILTEYKAML
>NC_015425.1|WP_019278276.1|174081_174561_+|transcription-elongation-factor-GreA
MSDSKQYIMTAEGVKKLEDELEYLKTTKRREITEKIKVALSYGDLSENSEYDEAKNEQAFVEGRIVQIENMLRNANVIDESEIPKDVVSVGAIVKVKDYDFDEEIDFHIVGSAEADPMENKISNESPVGSALIGKKVGDIVNVPVPDGISKFEILEIRI
>NC_015425.1|WP_162836943.1|174654_176142_+|lysine--tRNA-ligase
MEAKKEAEFNALVKERMQKLSNLQEQGKDPFDVYKVERTHTSQQIKDNYDELEGKNVTVAGRLMSKRVHGKAGFSDIRDRYGKIQLYIKIDDVGEEKLKEYKTFDIGDFVSITGTVFKTKTGEVTLHILDFKLLTKSLKPLPEKFHGLKDPDLRYRQRYVDLIMNEDVRETFMKRTAIIKAIREFLDNREFLEVETPILSPIAGGAAAKPFITHHNALDIDMYLRIATELYLKRLIVGGFEKVYEIGKNFRNEGIDIRHNPEFTAIELYEAYADYNDMMEITENMVAYVCEKVNGTTKVMYEGTEIDFKPPWRRITMVDAVKEFAGVDFNEVNTDEEAREIAKGKELELKKELKDCTKGDILVALFEEFGEEKLMQPTFVCDYPKENSPLTKKKRGNDALTERFEGFVYGREICNAYSELNDPIVQKERFVQQLKERELGDDEAYMMDDDFINALEIGMPPTGGLGIGIDRLIMFLTDSSSIRDVILFPTMKPTK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

26797 : 36105

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029169675.1\|26797_27010_+	DUF3006 domain-containing protein	Q0H256	Geobacillus_phage	9.3e-07	50.0
WP_013724266.1\|27289_28543_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.7e-109	52.3
WP_013724267.1\|28555_29695_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.5e-74	42.4
WP_013724268.1\|29847_30654_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	3.5e-38	36.2
WP_013724269.1\|30926_32339_+	FAD-binding protein	A0A218MMS0	uncultured_virus	7.1e-26	26.2
WP_013724270.1\|32418_33702_+	adenylosuccinate synthase	A0A285PX35	Cedratvirus	3.3e-62	34.4
WP_013724271.1\|33770_33962_+	DUF1858 domain-containing protein	NA	NA	NA	NA
WP_013724272.1\|34050_34794_+	acyl-ACP thioesterase	NA	NA	NA	NA
WP_013724273.1\|34860_36105_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	5.1e-12	37.1

DBSCAN-SWA_2

90882 : 121690

Streptococcus_phage(50.0%)

transposase,coat,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013724324.1\|90882_92307_+\|transposase	IS1182-like element ISCbo5 family transposase	A0A1X9I5T2	Streptococcus_phage	1.8e-77	38.6
WP_013724325.1\|92393_92972_-	50S ribosomal protein L25	NA	NA	NA	NA
WP_019278514.1\|93262_93910_+	hypothetical protein	NA	NA	NA	NA
WP_013724327.1\|93935_94799_-	phosphatase	NA	NA	NA	NA
WP_019278515.1\|95167_96298_+	ABC transporter permease	NA	NA	NA	NA
WP_013724330.1\|96299_97493_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_013724331.1\|97495_98203_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-32	38.0
WP_013724332.1\|98502_99186_+	nitrate/sulfite reductase	NA	NA	NA	NA
WP_013724333.1\|99325_99790_+	hypothetical protein	NA	NA	NA	NA
WP_013724334.1\|99789_100500_+	response regulator transcription factor	W8CYM9	Bacillus_phage	9.7e-40	36.9
WP_013724335.1\|100524_101970_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_013724336.1\|101959_102799_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013724337.1\|102897_103857_+	D-2-hydroxyacid dehydrogenase	Q89388	Paramecium_bursaria_Chlorella_virus	3.0e-20	28.8
WP_013724338.1\|103856_104036_+	hypothetical protein	NA	NA	NA	NA
WP_013724339.1\|104158_106219_+	hypothetical protein	NA	NA	NA	NA
WP_013724340.1\|106330_107386_+	hypothetical protein	NA	NA	NA	NA
WP_013724341.1\|107527_108583_+	sugar diacid recognition protein	NA	NA	NA	NA
WP_029169738.1\|108697_109954_+	GntP family permease	NA	NA	NA	NA
WP_013724343.1\|110190_111225_-\|transposase	IS6 family transposase	NA	NA	NA	NA
WP_029169766.1\|111348_112488_+	glycerate kinase	W6LM47	Streptococcus_phage	1.1e-45	37.4
WP_013724345.1\|112625_113261_+	HD domain-containing protein	NA	NA	NA	NA
WP_013724346.1\|113404_115198_+	EAL domain-containing protein	NA	NA	NA	NA
WP_013724347.1\|115221_115797_-	manganese catalase family protein	NA	NA	NA	NA
WP_013724348.1\|115818_116094_-\|coat	spore coat protein CotJB	NA	NA	NA	NA
WP_019278603.1\|116096_116321_-\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
WP_013724350.1\|116488_118366_+	DUF4396 domain-containing protein	NA	NA	NA	NA
WP_013724351.1\|118377_119592_+	cell wall-binding repeat-containing protein	NA	NA	NA	NA
WP_013724352.1\|119595_120168_+	hypothetical protein	NA	NA	NA	NA
WP_013724353.1\|120265_121690_-\|transposase	IS1182-like element ISCbo5 family transposase	A0A1X9I5T2	Streptococcus_phage	1.4e-77	38.6

DBSCAN-SWA_3

1173884 : 1183628

uncultured_Mediterranean_phage(83.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013725267.1\|1173884_1175015_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.6e-90	46.2
WP_013725268.1\|1175068_1175347_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.7e-06	33.0
WP_013725269.1\|1175405_1175774_+	TIGR04086 family membrane protein	NA	NA	NA	NA
WP_013725270.1\|1175848_1175986_+	six-cysteine peptide SCIFF	NA	NA	NA	NA
WP_013725271.1\|1176056_1177427_+	thioether cross-link-forming SCIFF peptide maturase	NA	NA	NA	NA
WP_013725272.1\|1177518_1178790_+	protein translocase subunit SecD	A0A1B1IVP7	uncultured_Mediterranean_phage	2.1e-05	28.6
WP_013725273.1\|1178790_1179660_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	4.1e-40	39.9
WP_013725274.1\|1179822_1180734_+	delta(24)-sterol C-methyltransferase	NA	NA	NA	NA
WP_013725275.1\|1180816_1181335_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.8e-28	43.8
WP_013725276.1\|1181435_1183628_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A1B1IUF0	uncultured_Mediterranean_phage	9.7e-14	38.3

DBSCAN-SWA_4

1296333 : 1329143

Clostridium_phage(42.31%)

portal,terminase,tail,head,plate,integrase

attL 1287766:1287783|attR 1327653:1327670

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1287766:1287783	attL	NA	NA	NA	NA
WP_013725394.1\|1296333_1297407_-\|integrase	site-specific integrase	B3GVW7	Streptococcus_phage	5.6e-31	32.5
WP_013725395.1\|1297523_1297988_-	ImmA/IrrE family metallo-endopeptidase	A0A0A7RVV2	Clostridium_phage	1.6e-38	54.9
WP_013725396.1\|1298006_1298456_-	helix-turn-helix transcriptional regulator	Q8SBN0	Clostridium_phage	4.7e-40	58.7
WP_013725397.1\|1298667_1298877_+	hypothetical protein	NA	NA	NA	NA
WP_013725398.1\|1298892_1299675_+	hypothetical protein	A0A288WG93	Bacillus_phage	4.9e-61	46.5
WP_013725399.1\|1299686_1299989_+	hypothetical protein	NA	NA	NA	NA
WP_013725400.1\|1300158_1300353_+	hypothetical protein	NA	NA	NA	NA
WP_013725401.1\|1300357_1300639_+	hypothetical protein	NA	NA	NA	NA
WP_019278333.1\|1300687_1301221_+	hypothetical protein	A0A0A7S0G6	Clostridium_phage	2.2e-49	55.4
WP_013725403.1\|1301232_1301829_+	ERF family protein	B6SBX8	Clostridium_virus	4.3e-49	51.0
WP_019278334.1\|1301840_1302032_+	hypothetical protein	NA	NA	NA	NA
WP_013725405.1\|1302050_1302887_+	DUF4373 domain-containing protein	A8ATL0	Listeria_phage	1.2e-44	40.4
WP_019278335.1\|1302861_1303554_+	ATP-binding protein	Q0H276	Geobacillus_phage	1.4e-35	39.1
WP_013725407.1\|1303566_1303731_+	hypothetical protein	NA	NA	NA	NA
WP_013725408.1\|1303769_1304192_+	hypothetical protein	NA	NA	NA	NA
WP_013725409.1\|1304246_1304414_+	hypothetical protein	NA	NA	NA	NA
WP_013725410.1\|1304410_1304590_+	hypothetical protein	NA	NA	NA	NA
WP_013725411.1\|1304601_1304883_+	hypothetical protein	NA	NA	NA	NA
WP_013725412.1\|1304908_1305229_+	hypothetical protein	A0A0A7RVR8	Clostridium_phage	6.3e-15	45.5
WP_013725413.1\|1305391_1305946_+	hypothetical protein	NA	NA	NA	NA
WP_013725414.1\|1305948_1306713_+	hypothetical protein	NA	NA	NA	NA
WP_019278337.1\|1306803_1306956_+	hypothetical protein	NA	NA	NA	NA
WP_013725416.1\|1306981_1307143_+	hypothetical protein	NA	NA	NA	NA
WP_013725417.1\|1307164_1307593_+	hypothetical protein	A0A0A7RTX6	Clostridium_phage	7.4e-11	32.5
WP_013725418.1\|1308346_1309027_+	hypothetical protein	NA	NA	NA	NA
WP_013725419.1\|1309075_1309240_+	hypothetical protein	NA	NA	NA	NA
WP_013725420.1\|1309288_1309750_+\|terminase	terminase small subunit	A0A0A8WDX8	Clostridium_phage	2.2e-29	50.3
WP_013725421.1\|1309742_1311002_+\|terminase	PBSX family phage terminase large subunit	B6CXD2	Clostridium_phage	1.6e-106	47.9
WP_013725422.1\|1311014_1312469_+\|portal	phage portal protein	A0A1S5SAF3	Streptococcus_phage	7.6e-132	52.4
WP_013725423.1\|1312455_1313727_+\|head	head protein	D2J057	Enterococcus_phage	1.6e-56	39.5
WP_013725424.1\|1313731_1313956_+	hypothetical protein	NA	NA	NA	NA
WP_013725425.1\|1314094_1314709_+	scaffold protein	A0A1S5SA01	Streptococcus_phage	7.4e-12	42.0
WP_013725426.1\|1314726_1315563_+	hypothetical protein	A0A1L2JY55	Aeribacillus_phage	1.6e-70	51.6
WP_013725427.1\|1315593_1316163_+	hypothetical protein	A0A1S5S8X7	Streptococcus_phage	4.7e-29	45.4
WP_013725428.1\|1316162_1316492_+\|head	phage head closure protein	A0A1S5SAE8	Streptococcus_phage	5.9e-08	31.8
WP_013725429.1\|1316484_1316925_+	HK97 gp10 family phage protein	A0A1S5SAB8	Streptococcus_phage	5.4e-33	55.3
WP_013725430.1\|1316934_1317303_+	hypothetical protein	NA	NA	NA	NA
WP_013725431.1\|1317304_1317931_+	hypothetical protein	A0A1S5S9Y8	Streptococcus_phage	1.6e-62	59.1
WP_013725432.1\|1317981_1318359_+	hypothetical protein	NA	NA	NA	NA
WP_019278339.1\|1318424_1318652_+	hypothetical protein	NA	NA	NA	NA
WP_019278340.1\|1318663_1321213_+\|tail	phage tail tape measure protein	A0A0A7S163	Clostridium_phage	2.0e-79	52.7
WP_013725435.1\|1321215_1321896_+	hypothetical protein	A0A0A7RWN1	Clostridium_phage	1.9e-45	44.4
WP_013725436.1\|1321897_1323205_+\|plate	BppU family phage baseplate upper protein	A0A0A7S181	Clostridium_phage	4.4e-30	47.7
WP_013725437.1\|1323221_1323440_+	hypothetical protein	NA	NA	NA	NA
WP_013725438.1\|1323546_1325235_+	endopeptidase	A0A0A7RUI9	Clostridium_phage	6.3e-138	67.1
WP_013725439.1\|1325298_1325562_+	hypothetical protein	NA	NA	NA	NA
WP_013725441.1\|1326564_1327128_+	DUF4352 domain-containing protein	A0A0S2MVG4	Bacillus_phage	8.0e-13	31.1
WP_029169461.1\|1327285_1327633_+	hypothetical protein	NA	NA	NA	NA
WP_019278342.1\|1327787_1329143_+	MBL fold metallo-hydrolase	Q332C0	Clostridium_botulinum_C_phage	9.8e-134	61.4
1327653:1327670	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1363175 : 1369987

Lactococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013725483.1\|1363175_1364054_+	site-specific tyrosine recombinase XerD	A0A1P8DJJ6	Virus_Rctr41k	3.5e-15	24.9
WP_080008825.1\|1364167_1365343_+	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	5.7e-05	30.1
WP_013725485.1\|1365678_1366431_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	2.3e-55	45.9
WP_013725486.1\|1366433_1367720_-\|transposase	IS21-like element ISCbo2 family transposase	A0A059NT83	Lactococcus_phage	6.4e-42	31.4
WP_013725487.1\|1368672_1369425_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.0e-07	27.1
WP_039240028.1\|1369411_1369987_+	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.6e-22	36.4

DBSCAN-SWA_6

1836512 : 1864872

Streptococcus_phage(33.33%)

protease,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013725912.1\|1836512_1837328_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_029169658.1\|1837629_1838445_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_019278200.1\|1838743_1839934_-	MFS transporter	NA	NA	NA	NA
WP_013725915.1\|1839996_1840422_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_013725916.1\|1840614_1840905_-	ethanolamine utilization microcompartment protein EutM	NA	NA	NA	NA
WP_013725917.1\|1840965_1841613_-	phosphate propanoyltransferase	NA	NA	NA	NA
WP_013725918.1\|1841613_1843245_-	acetaldehyde dehydrogenase (acetylating)	A0A1X9I5D4	Streptococcus_phage	7.7e-08	20.9
WP_029169510.1\|1843270_1843933_-	DUF861 domain-containing protein	NA	NA	NA	NA
WP_013725920.1\|1843966_1844230_-	EutN/CcmL family microcompartment protein	NA	NA	NA	NA
WP_013725921.1\|1844282_1845125_-	ethanolamine utilization protein EutJ	NA	NA	NA	NA
WP_013725922.1\|1845106_1845805_-	hypothetical protein	NA	NA	NA	NA
WP_013725923.1\|1845818_1846253_-	GTP-binding protein	NA	NA	NA	NA
WP_029169509.1\|1846249_1846603_-	BMC domain-containing protein	NA	NA	NA	NA
WP_013725925.1\|1846641_1847589_-\|holin	choline TMA-lyase-activating enzyme	A0A2P0VNQ0	Tetraselmis_virus	5.5e-14	27.3
WP_029169657.1\|1847720_1850261_-\|holin	choline trimethylamine-lyase	NA	NA	NA	NA
WP_029169656.1\|1850308_1851802_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_013725928.1\|1851842_1852151_-	BMC domain-containing protein	NA	NA	NA	NA
WP_013725929.1\|1852170_1852467_-	BMC domain-containing protein	NA	NA	NA	NA
WP_019278198.1\|1852518_1852785_-	hypothetical protein	NA	NA	NA	NA
WP_013725931.1\|1852771_1853881_-	membrane protein	NA	NA	NA	NA
WP_029169630.1\|1854424_1855255_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_013725933.1\|1855512_1856655_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_019278659.1\|1856966_1857314_+	hypothetical protein	NA	NA	NA	NA
WP_013725934.1\|1857365_1859381_-	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_013725935.1\|1859505_1860540_+\|transposase	IS6 family transposase	NA	NA	NA	NA
WP_013725936.1\|1860781_1862119_-	MATE family efflux transporter	NA	NA	NA	NA
WP_013725937.1\|1862272_1862845_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_013725938.1\|1863116_1863260_-	hypothetical protein	NA	NA	NA	NA
WP_013725939.1\|1863585_1864872_+\|transposase	IS21-like element ISCbo2 family transposase	A0A059NT83	Lactococcus_phage	2.6e-43	31.7

DBSCAN-SWA_7

1873413 : 1884221

Synechococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013725947.1\|1873413_1878408_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	6.2e-32	23.3
WP_013725948.1\|1878502_1880005_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.6e-39	50.3
WP_013725949.1\|1880032_1880644_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.1e-22	38.1
WP_013725950.1\|1880631_1881627_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	5.8e-67	45.1
WP_013725951.1\|1881635_1883012_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.9e-60	34.1
WP_013725952.1\|1883032_1883740_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	3.7e-39	41.0
WP_013725953.1\|1883741_1884221_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	9.1e-26	44.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage