CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015558	Streptococcus parauberis KCTC 11537, complete genome	1 crisprs	cas3,DinG,csm6,csa3,DEDDh	0	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015558_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015558_1

1826608-1826693

Orphan

Consensus_repeat	Method
TGTTGATAACCTTGGTTATTTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015558_1

>merge|NC_015558|1|1826608-1826693|CRISPRCasFinder
TGTTGATAACCTTGGTTATTTTGTTGATAATTATTTTGAGGTTGTTGGTTATTATTCTGAGGCTGTTGATAACCTTGGTTATTTTG

>NC_015558|1|1|1826608-1826693|CRISPRCasFinder
TGTTGATAACCTTGGTTATTTTG	TTGATAATTATTTTGAGGTTGTTGGTTATTATTCTGAGGC
TGTTGATAACCTTGGTTATTTTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015558.1\|WP_003108699.1\|1826004_1826493_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_015558.1\|WP_003108723.1\|1830926_1831118_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_041828628.1\|1824909_1825095_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_041828620.1\|1822792_1822972_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_013794416.1\|1827921_1828953_-\|DUF1351-domain-containing-protein	unknown	unknown	gnl\|CDD\|377772
NC_015558.1\|WP_003108729.1\|1831411_1831615_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NC_015558.1\|WP_003108696.1\|1825094_1825421_-\|DUF1372-family-protein	unknown	unknown	gnl\|CDD\|254062
NC_015558.1\|WP_013794414.1\|1823904_1824450_-\|DUF1642-domain-containing-protein	unknown	unknown	gnl\|CDD\|369557
NC_015558.1\|WP_041828629.1\|1825763_1826012_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_041828626.1\|1824439_1824682_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_041828623.1\|1823302_1823521_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_041828630.1\|1827386_1827920_-\|phosphoribosyl-ATP-diphosphatase	unknown	unknown	gnl\|CDD\|212147
NC_015558.1\|WP_041828622.1\|1823049_1823316_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_041828624.1\|1823513_1823915_-\|endodeoxyribonuclease-RusA	unknown	unknown	unknown
NC_015558.1\|WP_003108726.1\|1831192_1831375_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_151191588.1\|1829976_1830930_-\|DnaD-domain-protein	unknown	unknown	gnl\|CDD\|130775
NC_015558.1\|WP_041828632.1\|1829696_1829975_-\|hypothetical-protein	unknown	unknown	unknown
NC_015558.1\|WP_080560930.1\|1828956_1829628_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377346
NC_015558.1\|WP_080560929.1\|1827027_1827390_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_015558.1\|WP_013794418.1\|1831883_1832573_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225484

Protein	Function_ID	Function_description	E-value
NC_015558.1\|WP_041828630.1\|1827386_1827920_-\|phosphoribosyl-ATP-diphosphatase	gnl\|CDD\|212147	cd11540, NTP-PPase_u3, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea. This family corresponds to a group of uncharacterized hypothetical proteins from bacteria and archaea, showing a high sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, members in this family consist of a single MazG-like domain that contains a well conserved divalent ion-binding motif EXX[E/D].	1.08565e-24
NC_015558.1\|WP_003108699.1\|1826004_1826493_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.95629e-08
NC_015558.1\|WP_013794416.1\|1827921_1828953_-\|DUF1351-domain-containing-protein	gnl\|CDD\|377772	pfam07083, DUF1351, Protein of unknown function (DUF1351). This family consists of several bacterial and phage proteins of around 230 residues in length. The function of this family is unknown.	3.45154e-17
NC_015558.1\|WP_013794418.1\|1831883_1832573_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	2.2149e-21
NC_015558.1\|WP_080560930.1\|1828956_1829628_-\|hypothetical-protein	gnl\|CDD\|377346	pfam04404, ERF, ERF superfamily. The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family includes proteins related to ERF.	2.34363e-13
NC_015558.1\|WP_003108696.1\|1825094_1825421_-\|DUF1372-family-protein	gnl\|CDD\|254062	pfam07116, DUF1372, Protein of unknown function (DUF1372). This family consists of several Streptococcus bacteriophage sequences and related proteins from Streptococcus species. Members of this family are typically around 100 residues in length and their function is unknown.	6.00985e-07
NC_015558.1\|WP_151191588.1\|1829976_1830930_-\|DnaD-domain-protein	gnl\|CDD\|130775	TIGR01714, hypothetical_phage_protein, phage replisome organizer, putative, N-terminal region. This model represents the N-terminal domain of a small family of phage proteins. The protein contains a region of low-complexity sequence that reflects DNA direct repeats able to function as an origin of phage replication. The region covered by this model is N-terminal to the low-complexity region. [Mobile and extrachromosomal element functions, Prophage functions].	9.85133e-22
NC_015558.1\|WP_013794414.1\|1823904_1824450_-\|DUF1642-domain-containing-protein	gnl\|CDD\|369557	pfam07852, DUF1642, Protein of unknown function (DUF1642). The sequences making up this family are derived from various hypothetical phage and prophage proteins. The region in question is approximately 140 amino acids long.	1.68675e-12
NC_015558.1\|WP_003108729.1\|1831411_1831615_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00737569
NC_015558.1\|WP_080560929.1\|1827027_1827390_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.36669e-16

>NC_015558.1|WP_003108699.1|1826004_1826493_-|helix-turn-helix-transcriptional-regulator
MQVFDGAKVKENRKRFNLTQYELSAMTNITQARISDIERNVTTVRSEEIISLSRALICDKDNFYSDKKDVKVIMNTFKKGKKEVNSTKQRQIISPFSAYSKNLEYGIRKPETKQLELFDEKSLIGQDLSGFVIISNQEYTKLLDAKERLEKFENIFSEVKNE
>NC_015558.1|WP_041828629.1|1825763_1826012_-|hypothetical-protein
MNNKQYHEKVKVDLQCPFCGHCKIIKLLPFRKAVKCPSCGQKVFLEYAGRFKGELDKHDNFFHAYEPFKLDNINDDFRGVFK
>NC_015558.1|WP_003108696.1|1825094_1825421_-|DUF1372-family-protein
MKSKFKKIINLLKHLGNLWILISISVLPAFTYVKVDEIEKKIDVIEHKVQKPTIKYQTDSVGGIGYVSVKDGNVITVPGYGQFLLNDSEAAIIQVGDKVPSYVLKRGN
>NC_015558.1|WP_041828628.1|1824909_1825095_-|hypothetical-protein
MSEIKILDACCGSRLFWFDKNEEHTIFMDIRQETFKPLFGQQRGTTHWMTFMKFELTGNGG
>NC_015558.1|WP_041828626.1|1824439_1824682_-|hypothetical-protein
MKIEDIERIIAEYLKFRTDSNGYAVINVEDFLKYFRFSYEQLNSNDNHDHYFEWVIDKSGYRRKCKKCGEIFFEVITNED
>NC_015558.1|WP_013794414.1|1823904_1824450_-|DUF1642-domain-containing-protein
MKIEEALYLPVKREGFIYSTDNGECKSHYRTLDGEEVSSSFKAKTKEELLYQPKKEVPQMIFDVIESFDDDVDYLHQHMRRQSNEVREWLTHNERDFYEAWLAYPNITVEKEKLYTVEIPNPNTPAITVLARSIVGDVVMCNEFDTCWKNNSRYQLTEQEIRKDFDWAWQQKFQKEVANEL
>NC_015558.1|WP_041828624.1|1823513_1823915_-|endodeoxyribonuclease-RusA
MNFEFLLPRNTKNVDLNLVINSNDRFHFHKKARMTSQLKSLAHYEAITFKGIPFSEKNPCQVHVTVYSPTKSKLDPPNLYPTVKALVDGLTVAGIWKDDNYKIIQLMTFKYGGLSHKKGHYKIVLDIEEVKNV
>NC_015558.1|WP_041828623.1|1823302_1823521_-|hypothetical-protein
MFKLYFEINGETKLQSEHQTQSQAIDAVKQFIKDKSSLPVRNNWGMHIKNNELIIDYGAHNARYIIKGDVKL
>NC_015558.1|WP_041828622.1|1823049_1823316_-|hypothetical-protein
MLSYDRNKKEVVKIRLLNPYFEEEIEVSESYDDIKNQLKYYGLGNLNFITVTKRNYNKRIVDNTILINPKNFSSVEISKHIIDGDIKL
>NC_015558.1|WP_041828620.1|1822792_1822972_-|hypothetical-protein
MSLNKTRKRSIEKSKRDLQRHNKKKIEKATKQIALAIGYSNSIARSLFNNFAEAFNDKK
>NC_015558.1|WP_080560929.1|1827027_1827390_-|helix-turn-helix-transcriptional-regulator
MKNRIKELREQNNLTQEELANKINVTKLTISNWENDKNKIKSDDAKELAKIFGVSIDYLVGYVNENKNVEHDSDFVKITTAEFNDLWKARQELYDLKIALRILKNAMAFATNEEIEEKND
>NC_015558.1|WP_041828630.1|1827386_1827920_-|phosphoribosyl-ATP-diphosphatase
MEFIEISEKTKQWSIDRNLNTANPLKQFQKLNEEYGELNSGIAKDKPDVIKDSIGDCLVVLTILAQQLNIDDIDHLLLLGNSNYYTKGMASTESLILYGSKAIGEMASTLQNMTYNPGAINNIARVKFAIRNITGVLDKIAINFGFVTKHCFEFAYNEIKDRKGKMIDGVWVKEADL
>NC_015558.1|WP_013794416.1|1827921_1828953_-|DUF1351-domain-containing-protein
MVKDVTNSVPTTIDATIPQWKYSNENVVFLTNEQKLLYEQQVKKESEPYQNYISTIETYKSDQAILAALNNKDKSVNAARLQLERLYMKPITDLKNWLKVANKPMDKARTNLDKQIKEFKQRDKELKLSTVKSVFEQLAEAAELNIQLFDNYYKDFLKASDFKSDSYELKPVTIKKINDIFDKVQAEENLKKENIELIKESAADAELISTSYITLFERGAGLADVLKQIKEDAKAVELEKKAIEERRLAQEKAEDERKAEIERLAAENANANIKAYDTDTGEILEDDTFSHEPSETIAEVPNFEPSEPVTKILKITSHIGQSQIDALYEYLEDNFINYEELGE
>NC_015558.1|WP_080560930.1|1828956_1829628_-|hypothetical-protein
MKFKYRNAEDIYNKFKKIDSDWELIASDDLFEICGRLFVKSTVTVQRLVKDILEKREATAFAELDNVPVYKNGNQQMQIPQWTGAVGSYARKYALQGLFAIGEDDVDDLSNEIENNHQNSQYNNQPPQQPTQMSVPNNNQQQAPQNNQQSQQEPLIDNFQLDVIKKKIVQISNITNVPFEVVSNHILVSNNLNSFEQVGINSFNKFIKYLDNQIAKKLAKKGV
>NC_015558.1|WP_041828632.1|1829696_1829975_-|hypothetical-protein
MSENEKVIFTADQEFEYKKQADRMQEFYEMMHELSALSKIPLILGIVDDKNHTIEITSDLLHRVSHAIKDVLDGQEPDKAMHSVFNIEDIGE
>NC_015558.1|WP_151191588.1|1829976_1830930_-|DnaD-domain-protein
MTKKTKTKIYFWLRLDNNFFKNLAIKQLRRISGGDTYIIIYIKMMLLSLETEGFIYFEGVLDNIAEEIAMALDEQIEDVQMTLSYFTKKGLVQIGEDGAEMLQVPALIDQETNWNRYKRNQKKLEQSNESWKNSNHIPTNSNLIPTEIEIEKEIKIDKEIKIDKEKEVDTANGDQQPEYTFFDLCNDFKENLGHREKWTPLRMDDLRYWSQDYGNDLVREALVTAVRQGKSSFAYIDSILKNWERDGLTTVELVRNHEEQRKNKISKQSQQQKPNIPDWSKVNDPDYVEKTLSPEEQEEAKKKMLERLKKIREKEEE
>NC_015558.1|WP_003108723.1|1830926_1831118_-|hypothetical-protein
MTHTKFNIITILPAGSKLKDGTVLTEQTKFSSDEFEKNPLMLPADHPVNQFLLRISIDRWRAN
>NC_015558.1|WP_003108726.1|1831192_1831375_-|hypothetical-protein
MEELALSTVGYFIVLAVLVIVLIIILASECPVNIDIDTSEDNEQKETPAYLSRYGRIIQM
>NC_015558.1|WP_003108729.1|1831411_1831615_-|helix-turn-helix-domain-containing-protein
MSKNAFEKLIDDTGIKRKVIAERLDISRSSLYKKAKNPRKMGTDEMAEFADVLGIDTEAVFNAILKT
>NC_015558.1|WP_013794418.1|1831883_1832573_+|helix-turn-helix-domain-containing-protein
MLKKYRTINNMTMEELAEAVGKTKSTISKWESGTRAPKIYEIEDIAQYFDISPQRMMFGDNISKIQSIFENLNPDRQSAVIEFAEKQINDQENNVISINDSRKRISAYVEGVVAAGDGTYQEDNLHMEVNLIEDEVPDKYDTIAQVVGDSMEPVINNDDLLFIKVTSQVDPNEIGIFQINNKNFVKKLRRDYDGQYYLQSLNSKYDDIYFNEDDNIRTIGLVIDNYREV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015558_1	1.1\|1826631\|40\|NC_015558\|CRISPRCasFinder	1826631-1826670	40	MK448925	Streptococcus phage Javan386, complete genome	8408-8447	0	1.0
NC_015558_1	1.1\|1826631\|40\|NC_015558\|CRISPRCasFinder	1826631-1826670	40	MK448927	Streptococcus phage Javan394, complete genome	9549-9588	0	1.0

1. spacer 1.1|1826631|40|NC_015558|CRISPRCasFinder matches to MK448925 (Streptococcus phage Javan386, complete genome) position: , mismatch: 0, identity: 1.0

ttgataattattttgaggttgttggttattattctgaggc	CRISPR spacer
ttgataattattttgaggttgttggttattattctgaggc	Protospacer
****************************************

2. spacer 1.1|1826631|40|NC_015558|CRISPRCasFinder matches to MK448927 (Streptococcus phage Javan394, complete genome) position: , mismatch: 0, identity: 1.0

ttgataattattttgaggttgttggttattattctgaggc	CRISPR spacer
ttgataattattttgaggttgttggttattattctgaggc	Protospacer
****************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

582942 : 590391

Streptococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041828689.1\|582942_585144_-	sulfatase-like hydrolase/transferase	W6LM83	Streptococcus_phage	3.1e-262	67.8
WP_004234288.1\|585461_586622_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	7.9e-140	63.4
WP_013793827.1\|586621_587302_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	6.1e-92	70.7
WP_013793828.1\|587362_588541_+	chorismate synthase	A0A291AU41	Pandoravirus	4.4e-37	32.7
WP_013793829.1\|588588_588927_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	1.4e-20	43.8
WP_041828418.1\|589038_590391_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-34	26.7

DBSCAN-SWA_2

594813 : 603706

uncultured_Caudovirales_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003106565.1\|594813_596013_+	CapA family protein	A0A2H4J5Z6	uncultured_Caudovirales_phage	8.7e-41	31.6
WP_003105811.1\|596194_596509_+	50S ribosomal protein L21	NA	NA	NA	NA
WP_003103972.1\|596518_596842_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003104751.1\|596869_597163_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_003106566.1\|597376_598285_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	2.0e-05	27.2
WP_003106567.1\|598288_598735_+	signal peptidase II	NA	NA	NA	NA
WP_003106568.1\|598734_599622_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.4e-08	25.6
WP_003105283.1\|599827_600349_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_003105983.1\|600365_601622_+	uracil transporter	Q9KX94	Enterobacteria_phage	4.9e-63	38.1
WP_013793833.1\|601665_602598_+	aspartate carbamoyltransferase catalytic subunit	M1HGA5	Paramecium_bursaria_Chlorella_virus	2.0e-24	31.3
WP_013793834.1\|602617_603706_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	3.1e-61	36.7

DBSCAN-SWA_3

882545 : 927900

Streptococcus_phage(81.4%)

head,integrase,tail,capsid,portal,terminase,protease

attL 885119:885139|attR 927942:927962

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003104040.1\|882545_883244_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	9.6e-16	31.6
WP_003106994.1\|883252_884044_+	hypothetical protein	NA	NA	NA	NA
WP_013793981.1\|884086_884698_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	1.1e-47	50.5
885119:885139	attL	NA	NA	NA	NA
WP_041828424.1\|885340_885592_-	hypothetical protein	A0A1B0RX98	Streptococcus_phage	6.7e-12	48.1
WP_013793982.1\|885707_886679_-	DUF3825 domain-containing protein	A8ATW5	Listeria_phage	1.2e-35	37.0
WP_013793983.1\|886772_886964_-	CsbD family protein	J7KJ36	Streptococcus_phage	2.3e-12	60.3
WP_013793984.1\|887052_888300_-	N-acetylmuramoyl-L-alanine amidase	A0A0B5A075	Streptococcus_phage	4.3e-136	87.1
WP_013793985.1\|888303_888489_-	hypothetical protein	Q938J5	Temperate_phage	4.1e-19	83.1
WP_013793986.1\|888535_888856_-	hypothetical protein	D7RWE5	Brochothrix_phage	5.5e-19	53.7
WP_013793987.1\|889033_889363_-	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	2.2e-18	47.2
WP_013793988.1\|889411_891268_-	phage protein	A0A097PAT0	Streptococcus_pyogenes_phage	4.1e-98	36.9
WP_013793989.1\|891277_894526_-	hypothetical protein	A0A286QMY8	Streptococcus_phage	1.2e-169	33.5
WP_049775718.1\|894525_896082_-\|tail	phage tail protein	A0A286QPQ5	Streptococcus_phage	6.0e-151	50.0
WP_013793990.1\|896078_900587_-	transglycosylase SLT domain-containing protein	A0A2P0VJB7	Streptococcus_phage	0.0e+00	65.9
WP_013793991.1\|900761_901151_-\|tail	tail fiber protein	A0A2I6QQU1	Streptococcus_phage	2.4e-24	51.7
WP_013793992.1\|901215_901830_-\|tail	tail protein	A0A220GKE1	Streptococcus_phage	4.8e-80	72.4
WP_013793993.1\|901845_902220_-	DUF806 family protein	A0A286QQM7	Streptococcus_phage	1.1e-29	49.6
WP_013793994.1\|902223_902640_-\|tail	tail component protein	A0A286QQY0	Streptococcus_phage	7.6e-45	64.5
WP_041828425.1\|902641_902989_-\|head	phage head closure protein	A0A2I6QQX9	Streptococcus_phage	2.8e-32	61.6
WP_041828426.1\|902963_903308_-\|head,tail	phage gp6-like head-tail connector protein	A0A286QPH4	Streptococcus_phage	5.5e-25	55.6
WP_013793995.1\|903321_904509_-\|capsid	phage major capsid protein	A0A286QSM8	Streptococcus_phage	3.1e-139	65.1
WP_013793996.1\|904524_905220_-\|protease	Clp protease ClpP	A0A286QQD7	Streptococcus_phage	9.0e-83	72.1
WP_013793997.1\|905226_906345_-\|portal	phage portal protein	A0A2I6QR11	Streptococcus_phage	2.4e-141	65.8
WP_100190759.1\|906393_906579_-	DUF1056 family protein	A0A2I6QQZ6	Streptococcus_phage	1.6e-10	57.9
WP_013793998.1\|906587_908459_-\|terminase	terminase large subunit	A0A286QRK5	Streptococcus_phage	1.3e-285	75.8
WP_013793999.1\|908470_908932_-\|terminase	phage terminase small subunit P27 family	A0A286QRF4	Streptococcus_phage	7.4e-57	72.5
WP_013794000.1\|909886_910204_-	hypothetical protein	NA	NA	NA	NA
WP_013794001.1\|910424_910841_-	DUF722 domain-containing protein	A7J289	Streptococcus_phage	1.5e-61	82.6
WP_013794002.1\|910833_911136_-	helix-turn-helix transcriptional regulator	A3F633	Streptococcus_phage	1.4e-19	52.9
WP_151191592.1\|911175_911610_-	DUF1642 domain-containing protein	W6LLF4	Streptococcus_phage	1.6e-29	56.6
WP_049775719.1\|911899_912112_-	hypothetical protein	A0A0B5A5X4	Streptococcus_phage	3.1e-10	97.1
WP_013794004.1\|912271_912664_-	DUF3310 domain-containing protein	A1EAD4	Streptococcus_phage	1.5e-29	83.3
WP_013794005.1\|912667_913993_-	DEAD/DEAH box helicase	A7J284	Streptococcus_phage	2.7e-221	84.0
WP_013794007.1\|914641_917038_-	DNA primase	A7J282	Streptococcus_phage	1.7e-253	84.3
WP_013794008.1\|917042_918965_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	85.9
WP_013794009.1\|919007_919571_-	DUF2815 family protein	D2J040	Enterococcus_phage	3.9e-52	58.2
WP_013794010.1\|919583_920738_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	4.1e-189	82.9
WP_013794011.1\|920737_921079_-	hypothetical protein	A7J277	Streptococcus_phage	8.8e-15	49.6
WP_013794012.1\|921170_921383_-	hypothetical protein	A7J276	Streptococcus_phage	4.0e-10	57.6
WP_041828427.1\|921603_921786_-	hypothetical protein	NA	NA	NA	NA
WP_041828428.1\|921913_922162_-	helix-turn-helix domain-containing protein	A0A0B5A536	Streptococcus_phage	2.8e-39	96.3
WP_080560916.1\|922244_922448_-	helix-turn-helix transcriptional regulator	Q6SE98	Lactobacillus_prophage	3.6e-08	45.9
WP_080560917.1\|922571_922787_+	hypothetical protein	NA	NA	NA	NA
WP_013794013.1\|923140_923332_-	hypothetical protein	A7J270	Streptococcus_phage	1.3e-23	87.3
WP_041828430.1\|923402_923618_+	hypothetical protein	NA	NA	NA	NA
WP_013794014.1\|923830_924301_+	hypothetical protein	NA	NA	NA	NA
WP_041828431.1\|924262_924454_-	hypothetical protein	NA	NA	NA	NA
WP_041828432.1\|924523_924721_+	hypothetical protein	NA	NA	NA	NA
WP_013794015.1\|925181_925535_+	helix-turn-helix transcriptional regulator	M1I9X0	Streptococcus_phage	1.8e-42	75.9
WP_041828433.1\|925538_925883_+	phage protein	A3F612	Streptococcus_phage	1.4e-28	55.0
WP_013794016.1\|925894_926320_+	hypothetical protein	NA	NA	NA	NA
WP_013794017.1\|926811_927900_+\|integrase	site-specific integrase	Q38159	Streptococcus_phage	3.1e-170	82.3
927942:927962	attR	NA	NA	NA	NA

DBSCAN-SWA_4

956566 : 964464

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041828438.1\|956566_957172_-	acetyltransferase	A0A2K9L5T5	Tupanvirus	1.7e-13	41.6
WP_013794034.1\|957164_957785_-	sugar transferase	NA	NA	NA	NA
WP_013794035.1\|957801_959028_-	aminotransferase class V-fold PLP-dependent enzyme	A0A2K9L470	Tupanvirus	1.5e-27	29.6
WP_013794036.1\|959031_960834_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	6.5e-24	28.7
WP_013794037.1\|960837_961557_-	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	3.6e-58	54.0
WP_003108307.1\|961567_962260_-	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	2.5e-48	48.5
WP_013794038.1\|962268_963000_-	tyrosine protein phosphatase	NA	NA	NA	NA
WP_003107044.1\|963000_964464_-	LCP family protein	A0A1X9I5X1	Streptococcus_phage	4.7e-105	49.5

DBSCAN-SWA_5

1368014 : 1452779

114

Streptococcus_phage(48.28%)

integrase,tail,holin,portal,terminase

attL 1362849:1362866|attR 1455848:1455865

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1362849:1362866	attL	NA	NA	NA	NA
WP_003108116.1\|1368014_1368617_+	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	1.1e-23	35.9
WP_013794219.1\|1368609_1370832_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_013794220.1\|1370861_1372196_-	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	2.5e-65	33.9
WP_003108114.1\|1372287_1373112_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	3.8e-72	56.4
WP_003105446.1\|1373108_1374569_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.9e-104	42.7
WP_041828469.1\|1374795_1375050_-	hypothetical protein	E4ZFJ0	Streptococcus_phage	1.5e-11	56.5
WP_013794221.1\|1375101_1376391_-	peptidoglycan endolysin	A0A0B5A075	Streptococcus_phage	5.9e-128	81.4
WP_041828470.1\|1376394_1376673_-\|holin	phage holin	A0A0B5A2E7	Streptococcus_phage	1.7e-40	91.3
WP_013794222.1\|1376669_1376990_-	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	2.4e-30	58.7
WP_151191585.1\|1377168_1379820_-	SGNH/GDSL hydrolase family protein	A0A0B5A5V2	Streptococcus_phage	4.1e-83	39.5
WP_013794224.1\|1379801_1382756_-	hypothetical protein	A0A0B5A7F4	Streptococcus_phage	0.0e+00	90.1
WP_013794226.1\|1384247_1386449_-	hypothetical protein	A0A097PAU2	Streptococcus_pyogenes_phage	1.5e-102	47.6
WP_041828473.1\|1386441_1386903_-	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	4.3e-57	70.6
WP_041828475.1\|1386875_1387196_-	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	1.1e-35	69.9
WP_013794228.1\|1387209_1387737_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.8e-62	78.7
WP_013794230.1\|1388155_1388557_-	hypothetical protein	A0A097PAT9	Streptococcus_pyogenes_phage	2.1e-36	64.0
WP_041828476.1\|1388553_1388868_-	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	2.7e-26	55.8
WP_013794231.1\|1388864_1389200_-	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	5.6e-22	52.7
WP_013794232.1\|1389368_1390268_-	hypothetical protein	A0A097PAW2	Streptococcus_pyogenes_phage	9.0e-67	77.5
WP_041828478.1\|1390283_1390856_-	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	2.5e-22	39.9
WP_041828481.1\|1391334_1391634_-	hypothetical protein	NA	NA	NA	NA
WP_041828483.1\|1391785_1392094_-	hypothetical protein	NA	NA	NA	NA
WP_013794234.1\|1392659_1393580_-	hypothetical protein	A0A097PBF2	Streptococcus_pyogenes_phage	2.6e-53	61.8
WP_013794235.1\|1393590_1395129_-\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	8.5e-166	69.5
WP_041828484.1\|1395128_1396352_-\|terminase	PBSX family phage terminase large subunit	O34057	Streptococcus_phage	6.1e-183	76.1
WP_041828486.1\|1396338_1396827_-\|terminase	terminase small subunit	O34056	Streptococcus_phage	1.1e-47	62.3
WP_041828487.1\|1397665_1398100_-	DUF1492 domain-containing protein	A0A0B5A564	Streptococcus_phage	2.6e-32	56.5
WP_041828489.1\|1398369_1398615_-	hypothetical protein	A0A0B5A0A0	Streptococcus_phage	4.5e-37	90.1
WP_049775732.1\|1398956_1399529_-	DUF1642 domain-containing protein	W6LLF4	Streptococcus_phage	3.4e-27	49.2
WP_041828490.1\|1399518_1399761_-	hypothetical protein	NA	NA	NA	NA
WP_041828492.1\|1399757_1400144_-	hypothetical protein	NA	NA	NA	NA
WP_041828494.1\|1400324_1400546_-	hypothetical protein	NA	NA	NA	NA
WP_041828495.1\|1400542_1400725_-	hypothetical protein	D6PSV1	Lactobacillus_phage	6.5e-09	56.9
WP_041828496.1\|1400727_1401138_-	hypothetical protein	D2IZL0	Enterococcus_phage	1.4e-11	40.0
WP_013794237.1\|1401134_1401422_-	hypothetical protein	NA	NA	NA	NA
WP_049775733.1\|1401418_1401787_-	DUF1642 domain-containing protein	A0A0B5A2G5	Streptococcus_phage	3.6e-30	56.6
WP_041828498.1\|1401779_1402025_-	hypothetical protein	NA	NA	NA	NA
WP_041828499.1\|1402021_1402471_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	8.8e-39	54.4
WP_041828500.1\|1402647_1403637_-	DUF1351 domain-containing protein	A0A060QNS1	Streptococcus_phage	3.3e-102	58.9
WP_013794238.1\|1403647_1404418_-	phage recombination protein Bet	M1PFN1	Streptococcus_phage	6.5e-90	83.5
WP_013794239.1\|1404773_1405121_-	hypothetical protein	NA	NA	NA	NA
WP_041828502.1\|1405117_1405345_-	hypothetical protein	Q938N1	Temperate_phage	1.4e-21	65.8
WP_013794241.1\|1405850_1406102_-	replication protein	A0A060QMU7	Streptococcus_phage	6.4e-15	49.4
WP_041828504.1\|1406216_1406441_-	hypothetical protein	J7KBY5	Streptococcus_phage	5.5e-26	73.0
WP_041828506.1\|1406471_1406726_-	hypothetical protein	NA	NA	NA	NA
WP_041828507.1\|1406739_1406925_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_041828509.1\|1407006_1407210_-	helix-turn-helix transcriptional regulator	Q6SE98	Lactobacillus_prophage	1.4e-07	44.3
WP_041828510.1\|1407309_1407522_+	hypothetical protein	NA	NA	NA	NA
WP_041828511.1\|1407502_1407769_-	hypothetical protein	NA	NA	NA	NA
WP_013794242.1\|1407979_1408705_-	oxidoreductase	Q938N5	Temperate_phage	7.9e-106	77.9
WP_041828512.1\|1408732_1408945_-	helix-turn-helix transcriptional regulator	A0A141E0W0	Streptococcus_phage	1.5e-25	85.5
WP_041828514.1\|1408997_1409381_+	DUF2513 domain-containing protein	A0A2H4J4K9	uncultured_Caudovirales_phage	9.9e-15	34.6
WP_013794243.1\|1409744_1410500_+	helix-turn-helix domain-containing protein	A0A1S5SD15	Streptococcus_phage	1.5e-86	62.1
WP_013794244.1\|1410568_1411336_+	NINE protein	A0A097BY93	Leuconostoc_phage	5.0e-10	57.4
WP_013794245.1\|1411493_1412591_+\|integrase	site-specific integrase	Q938N9	Temperate_phage	1.2e-129	62.7
WP_041828469.1\|1412872_1413127_-	hypothetical protein	E4ZFJ0	Streptococcus_phage	1.5e-11	56.5
WP_013794221.1\|1413178_1414468_-	peptidoglycan endolysin	A0A0B5A075	Streptococcus_phage	5.9e-128	81.4
WP_041828470.1\|1414471_1414750_-\|holin	phage holin	A0A0B5A2E7	Streptococcus_phage	1.7e-40	91.3
WP_013794222.1\|1414746_1415067_-	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	2.4e-30	58.7
WP_151191585.1\|1415245_1417897_-	SGNH/GDSL hydrolase family protein	A0A0B5A5V2	Streptococcus_phage	4.1e-83	39.5
WP_013794246.1\|1417878_1420830_-	hypothetical protein	A0A0B5A7F4	Streptococcus_phage	0.0e+00	87.2
WP_013794247.1\|1420830_1422315_-	hypothetical protein	A0A097PAW9	Streptococcus_pyogenes_phage	3.8e-163	56.2
WP_041828515.1\|1424503_1424965_-	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	2.4e-55	71.7
WP_041828516.1\|1424937_1425255_-	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	6.6e-41	77.1
WP_013794249.1\|1425270_1425777_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	6.6e-67	84.7
WP_041828518.1\|1425789_1426200_-	DUF5072 domain-containing protein	A0A097PAW5	Streptococcus_pyogenes_phage	6.1e-55	77.2
WP_041828519.1\|1426203_1426605_-	antigen C	A0A097PAT9	Streptococcus_pyogenes_phage	7.1e-40	70.2
WP_041828520.1\|1426601_1426913_-	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	2.7e-26	58.3
WP_013794250.1\|1426909_1427251_-	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	1.1e-38	75.7
WP_041828521.1\|1427259_1427541_-	hypothetical protein	A0A097PBF3	Streptococcus_pyogenes_phage	4.8e-27	68.1
WP_041828523.1\|1427554_1428445_-	hypothetical protein	A0A097PAW2	Streptococcus_pyogenes_phage	2.1e-68	77.3
WP_013794251.1\|1428460_1429033_-	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	3.3e-38	53.7
WP_041828481.1\|1429351_1429651_-	hypothetical protein	NA	NA	NA	NA
WP_041828525.1\|1429802_1430087_-	hypothetical protein	NA	NA	NA	NA
WP_041828526.1\|1430087_1430375_-	hypothetical protein	A0A1S5SA91	Streptococcus_phage	8.4e-19	52.7
WP_013794252.1\|1430495_1431416_-	hypothetical protein	A0A097PBF2	Streptococcus_pyogenes_phage	4.6e-58	64.8
WP_013794253.1\|1431402_1432713_-\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	1.0e-159	65.7
WP_041828527.1\|1432712_1433933_-\|terminase	PBSX family phage terminase large subunit	W6LLG2	Streptococcus_phage	2.5e-189	78.6
WP_041828529.1\|1433919_1434408_-\|terminase	terminase small subunit	A0A1S5SF14	Streptococcus_phage	1.1e-47	60.6
WP_041828530.1\|1435125_1435575_-	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	1.8e-55	79.3
WP_041828531.1\|1436024_1436393_-	hypothetical protein	NA	NA	NA	NA
WP_041828532.1\|1436389_1436605_-	hypothetical protein	A0A0B5A7H3	Streptococcus_phage	5.3e-34	94.3
WP_041828533.1\|1436601_1436847_-	hypothetical protein	A0A0B5A0A0	Streptococcus_phage	8.2e-39	93.8
WP_041828535.1\|1436843_1437062_-	hypothetical protein	J7KDL2	Streptococcus_phage	5.1e-08	50.7
WP_041828536.1\|1437058_1437250_-	hypothetical protein	NA	NA	NA	NA
WP_151191595.1\|1437246_1437738_-	DUF1642 domain-containing protein	W6LLF4	Streptococcus_phage	1.4e-34	59.1
WP_013794256.1\|1437816_1438452_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.2e-99	83.3
WP_013794257.1\|1438489_1438912_-	hypothetical protein	A0A141E1Q1	Streptococcus_phage	4.8e-55	72.9
WP_041828538.1\|1438914_1439106_-	hypothetical protein	NA	NA	NA	NA
WP_151191596.1\|1439108_1439309_-	hypothetical protein	A0A0B5A5X4	Streptococcus_phage	7.9e-08	91.4
WP_041828542.1\|1439329_1439617_-	hypothetical protein	NA	NA	NA	NA
WP_080560926.1\|1439613_1439976_-	DUF1642 domain-containing protein	A0A0B5A2G5	Streptococcus_phage	3.7e-19	52.0
WP_041828543.1\|1439978_1440215_-	hypothetical protein	NA	NA	NA	NA
WP_041828544.1\|1440211_1440571_-	hypothetical protein	NA	NA	NA	NA
WP_041828546.1\|1440567_1441017_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	5.2e-39	54.4
WP_013794258.1\|1441360_1442158_-	hypothetical protein	J7KGZ1	Streptococcus_phage	1.4e-111	73.2
WP_013794259.1\|1442150_1443086_-	recombinase RecT	Q708Q2	Streptococcus_phage	2.2e-108	69.9
WP_041828551.1\|1443240_1443450_-	hypothetical protein	NA	NA	NA	NA
WP_041828552.1\|1443436_1443778_-	hypothetical protein	NA	NA	NA	NA
WP_041828554.1\|1443755_1444001_-	hypothetical protein	Q938N1	Temperate_phage	1.4e-14	50.7
WP_013794260.1\|1444034_1444790_-	DnaD domain protein	L0P704	Lactobacillus_phage	2.9e-34	58.8
WP_041828556.1\|1444801_1445026_-	hypothetical protein	J7KBY5	Streptococcus_phage	2.1e-25	71.6
WP_041828509.1\|1445392_1445596_-	helix-turn-helix transcriptional regulator	Q6SE98	Lactobacillus_prophage	1.4e-07	44.3
WP_080560927.1\|1445719_1445935_+	hypothetical protein	NA	NA	NA	NA
WP_013794261.1\|1445849_1446251_-	hypothetical protein	NA	NA	NA	NA
WP_041828728.1\|1446461_1447190_-	oxidoreductase	A0A141E1D3	Streptococcus_phage	4.0e-97	73.4
WP_041828558.1\|1447201_1447429_-	helix-turn-helix transcriptional regulator	A0A1X9I5Q5	Streptococcus_phage	9.0e-16	64.2
WP_041828514.1\|1447481_1447865_+	DUF2513 domain-containing protein	A0A2H4J4K9	uncultured_Caudovirales_phage	9.9e-15	34.6
WP_141768389.1\|1448211_1448961_+	helix-turn-helix domain-containing protein	E8ZDN4	Streptococcus_phage	3.6e-85	64.9
WP_013794264.1\|1449029_1449458_+	hypothetical protein	A0A1X9I6G5	Streptococcus_phage	2.5e-19	50.5
WP_013794265.1\|1449622_1450720_+\|integrase	site-specific integrase	Q938N9	Temperate_phage	2.9e-120	58.9
WP_013794266.1\|1450860_1451508_-	DUF1648 domain-containing protein	NA	NA	NA	NA
WP_004234704.1\|1451494_1451776_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003106271.1\|1451951_1452779_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.5e-129	81.0
1455848:1455865	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1455916 : 1466855

Streptococcus_phage(81.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003106258.1\|1455916_1456276_-	Spx/MgsR family RNA polymerase-binding regulatory protein	M1PLC0	Streptococcus_phage	4.0e-34	59.3
WP_003106256.1\|1456272_1456773_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.4e-37	51.6
WP_013794268.1\|1456841_1458017_-	3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	1.2e-172	78.4
WP_004234714.1\|1458064_1458613_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	9.1e-46	51.7
WP_003106251.1\|1458635_1459727_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	4.8e-163	76.5
WP_003106250.1\|1459843_1460476_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_003104681.1\|1460503_1460899_-	hypothetical protein	NA	NA	NA	NA
WP_003102867.1\|1461919_1462243_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	6.3e-31	61.0
WP_003104246.1\|1462232_1463033_-	signal peptidase II	NA	NA	NA	NA
WP_003104949.1\|1463029_1463905_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.3e-74	50.7
WP_003105765.1\|1463917_1464574_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.6e-68	63.5
WP_003106248.1\|1464636_1465299_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.2e-60	55.6
WP_003106074.1\|1465380_1466091_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.2e-17	32.4
WP_003103139.1\|1466090_1466855_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-17	25.3

DBSCAN-SWA_7

1482066 : 1494482

Streptococcus_phage(50.0%)

integrase

attL 1482374:1482388|attR 1498967:1498981

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003103661.1\|1482066_1482858_-	pyruvate formate lyase-activating protein	A0A2P0VNQ0	Tetraselmis_virus	1.1e-23	30.5
1482374:1482388	attL	NA	NA	NA	NA
WP_003106235.1\|1482930_1484265_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_013794276.1\|1484427_1484970_-	SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	4.9e-36	44.9
WP_003105061.1\|1484979_1485765_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_003104290.1\|1485761_1486595_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.7e-24	32.2
WP_037619743.1\|1486587_1487541_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	1.3e-36	51.8
WP_013794278.1\|1487653_1488814_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	3.0e-123	56.7
WP_013794279.1\|1489039_1489570_-	helix-turn-helix domain-containing protein	A0A1X9I723	Streptococcus_phage	9.5e-16	69.8
WP_013794280.1\|1489928_1490546_+	hypothetical protein	A0A192Y918	Salmonella_phage	1.9e-12	39.8
WP_041828561.1\|1490571_1490751_+	hypothetical protein	NA	NA	NA	NA
WP_003103900.1\|1490918_1491098_+	hypothetical protein	NA	NA	NA	NA
WP_041828562.1\|1491084_1491393_+	hypothetical protein	NA	NA	NA	NA
WP_041828564.1\|1491385_1491580_+	hypothetical protein	NA	NA	NA	NA
WP_013794281.1\|1491591_1491864_+	helix-turn-helix transcriptional regulator	A0A1X9I5U9	Streptococcus_phage	9.4e-20	53.5
WP_013794282.1\|1491999_1492866_+	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	8.9e-88	56.1
WP_013794283.1\|1492907_1494482_+	DNA primase	A0A1X9I717	Streptococcus_phage	5.3e-163	53.7
1498967:1498981	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1745094 : 1832573

Streptococcus_phage(72.09%)

tRNA,tail,holin,capsid,portal,terminase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013794378.1\|1745094_1745976_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_004235411.1\|1746819_1747857_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_004235414.1\|1748828_1749167_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013794379.1\|1749808_1750318_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	3.1e-40	55.8
WP_013794380.1\|1750382_1752098_-	alkaline phosphatase	NA	NA	NA	NA
WP_004235433.1\|1752342_1752978_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_013794382.1\|1752987_1754112_-	ABC transporter permease	NA	NA	NA	NA
WP_003105277.1\|1754113_1754830_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.6e-24	30.0
WP_004347143.1\|1755160_1756333_+	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_004235441.1\|1756399_1757503_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	Q6GZ03	Mycoplasma_phage	1.5e-26	34.0
WP_004235442.1\|1757489_1758251_-	HAD family hydrolase	NA	NA	NA	NA
WP_041828610.1\|1758250_1759744_-	hypothetical protein	NA	NA	NA	NA
WP_041828611.1\|1759763_1761071_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_045406944.1\|1761112_1761967_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_003105195.1\|1761976_1762861_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_003104461.1\|1762864_1763182_-	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_004235451.1\|1763438_1763729_-	hypothetical protein	NA	NA	NA	NA
WP_004235454.1\|1763737_1764406_-	fructose-6-phosphate aldolase	E3SKN5	Synechococcus_phage	8.3e-25	34.7
WP_013794383.1\|1764432_1766847_-	glycyl radical protein	NA	NA	NA	NA
WP_004347156.1\|1767006_1768272_-	reactive intermediate/imine deaminase	NA	NA	NA	NA
WP_013794384.1\|1768929_1769286_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_003102756.1\|1769410_1770184_+	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_003105842.1\|1770256_1770613_-	DUF2200 family protein	NA	NA	NA	NA
WP_004347158.1\|1772744_1773602_+	hypothetical protein	M1PFV6	Streptococcus_phage	1.6e-25	57.4
WP_003104670.1\|1773614_1774886_+	hypothetical protein	M1PLC8	Streptococcus_phage	4.3e-131	66.3
WP_013794386.1\|1775016_1777278_+	bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB	NA	NA	NA	NA
WP_013794389.1\|1779502_1781008_+	transcriptional regulator	NA	NA	NA	NA
WP_003108619.1\|1781035_1781908_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_013794390.1\|1781894_1782872_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_013794391.1\|1782889_1783519_+	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	7.7e-49	47.9
WP_003104647.1\|1783613_1784417_-	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	1.8e-10	31.2
WP_013794392.1\|1784425_1785310_-	ABC transporter permease	NA	NA	NA	NA
WP_003105619.1\|1787779_1788178_-	single-stranded DNA-binding protein	A0A1X9IGF2	Lactococcus_phage	5.8e-26	42.8
WP_013794394.1\|1788315_1788942_-\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_003103432.1\|1788957_1789275_-	thioredoxin family protein	NA	NA	NA	NA
WP_003102775.1\|1789274_1789556_-	DUF4651 domain-containing protein	NA	NA	NA	NA
WP_003105090.1\|1789918_1790986_+	glutamyl aminopeptidase	NA	NA	NA	NA
WP_003104671.1\|1790997_1791768_+	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_013794395.1\|1791784_1792438_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_003108636.1\|1792890_1793103_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003108638.1\|1793213_1794407_-	acetate kinase	NA	NA	NA	NA
WP_003103712.1\|1794462_1795419_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_080560935.1\|1796412_1796688_-	competence protein ComGE	NA	NA	NA	NA
WP_049775746.1\|1796648_1796996_-	hypothetical protein	NA	NA	NA	NA
WP_013794397.1\|1797078_1797399_-	competence protein ComG	NA	NA	NA	NA
WP_013794398.1\|1798051_1798777_-	lysin	Q2I7P1	Streptococcus_phage	7.4e-104	78.7
WP_013794399.1\|1798769_1799234_-\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	3.1e-47	62.7
WP_013794400.1\|1799449_1799788_-	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	2.9e-18	51.2
WP_013794401.1\|1799836_1801693_-	phage protein	A0A097PAT0	Streptococcus_pyogenes_phage	1.8e-98	36.6
WP_013794404.1\|1805246_1806692_-\|tail	tail protein	A0A286QQK5	Streptococcus_phage	8.2e-70	36.3
WP_013794405.1\|1806688_1810495_-	tape measure protein	A0A1P8VVL4	Streptococcus_phage	7.9e-189	64.2
WP_041828613.1\|1810514_1811102_-	phage protein	A0A1P8VVK8	Streptococcus_phage	4.6e-72	67.0
WP_041828614.1\|1811528_1811984_-	hypothetical protein	A0A1P8VVM4	Streptococcus_phage	9.5e-57	72.7
WP_003108657.1\|1811986_1812394_-\|capsid	phage capsid protein	A0A1P8VVK7	Streptococcus_phage	7.4e-53	77.3
WP_003108659.1\|1812394_1812751_-\|capsid	phage capsid protein	A0A1P8VVL8	Streptococcus_phage	1.0e-34	60.2
WP_041828616.1\|1812750_1813077_-\|capsid	phage capsid protein	K4K7N7	Streptococcus_phage	2.1e-34	61.1
WP_013794407.1\|1813066_1813456_-	hypothetical protein	K4JXK7	Streptococcus_phage	9.0e-40	67.2
WP_003108665.1\|1813496_1813748_-	hypothetical protein	A0A1P8VVQ1	Streptococcus_phage	1.5e-08	48.1
WP_003108667.1\|1813759_1814644_-	hypothetical protein	A0A1P8VVM7	Streptococcus_phage	3.4e-111	70.4
WP_013794408.1\|1814666_1815245_-	scaffold protein	A0A1C9LX53	Streptococcus_phage	1.1e-41	49.7
WP_013794409.1\|1815380_1816493_-\|capsid	phage capsid protein	K4JXL1	Streptococcus_phage	4.6e-145	70.4
WP_013794410.1\|1816548_1818066_-\|portal	phage portal protein	M1IFC5	Streptococcus_phage	5.7e-223	78.3
WP_013794411.1\|1818128_1819439_-\|terminase	PBSX family phage terminase large subunit	U4KJA9	Streptococcus_phage	5.1e-204	77.5
WP_013794412.1\|1820010_1820826_-	hypothetical protein	A0A1S5SDW7	Streptococcus_phage	5.0e-40	43.9
WP_041828618.1\|1820829_1821156_-	hypothetical protein	NA	NA	NA	NA
WP_013794413.1\|1821199_1822300_-	DUF4417 domain-containing protein	A0A1S5S8J8	Streptococcus_phage	5.2e-141	67.3
WP_041828619.1\|1822419_1822806_-	hypothetical protein	A0A1S5SED1	Streptococcus_phage	2.0e-23	43.1
WP_041828620.1\|1822792_1822972_-	hypothetical protein	NA	NA	NA	NA
WP_041828622.1\|1823049_1823316_-	hypothetical protein	NA	NA	NA	NA
WP_041828623.1\|1823302_1823521_-	hypothetical protein	NA	NA	NA	NA
WP_041828624.1\|1823513_1823915_-	endodeoxyribonuclease RusA	A0A141DZF7	Streptococcus_phage	3.8e-41	60.0
WP_013794414.1\|1823904_1824450_-	DUF1642 domain-containing protein	Q938L9	Temperate_phage	1.7e-20	44.4
WP_041828626.1\|1824439_1824682_-	hypothetical protein	NA	NA	NA	NA
WP_041828628.1\|1824909_1825095_-	hypothetical protein	A0A097PAU8	Streptococcus_pyogenes_phage	1.5e-13	33.8
WP_003108696.1\|1825094_1825421_-	DUF1372 family protein	NA	NA	NA	NA
WP_041828629.1\|1825763_1826012_-	hypothetical protein	A0A1S5SEE7	Streptococcus_phage	7.3e-19	55.4
WP_003108699.1\|1826004_1826493_-	helix-turn-helix transcriptional regulator	K4JTK7	Streptococcus_phage	1.6e-22	40.4
WP_013794415.1\|1826507_1827035_-	single-stranded DNA-binding protein	M1IRC1	Streptococcus_phage	5.5e-48	77.1
WP_080560929.1\|1827027_1827390_-	helix-turn-helix transcriptional regulator	A0A2P0VHA0	Streptococcus_phage	9.6e-12	59.4
WP_041828630.1\|1827386_1827920_-	phosphoribosyl-ATP diphosphatase	M1I9W2	Streptococcus_phage	5.4e-27	41.2
WP_013794416.1\|1827921_1828953_-	DUF1351 domain-containing protein	A0A141DZG5	Streptococcus_phage	2.5e-28	33.6
WP_080560930.1\|1828956_1829628_-	hypothetical protein	A0A097PBE8	Streptococcus_pyogenes_phage	1.5e-26	55.2
WP_041828632.1\|1829696_1829975_-	hypothetical protein	NA	NA	NA	NA
WP_151191588.1\|1829976_1830930_-	DnaD domain protein	A0A2I6QQV2	Streptococcus_phage	5.6e-35	42.4
WP_003108723.1\|1830926_1831118_-	hypothetical protein	NA	NA	NA	NA
WP_003108726.1\|1831192_1831375_-	hypothetical protein	NA	NA	NA	NA
WP_003108729.1\|1831411_1831615_-	helix-turn-helix domain-containing protein	A0A1X9I5S3	Streptococcus_phage	1.0e-10	50.0
WP_013794418.1\|1831883_1832573_+	helix-turn-helix domain-containing protein	A0A1S5S8S8	Streptococcus_phage	2.9e-57	49.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage