CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017272	Thermus thermophilus SG0.5JP17-16, complete genome	2 crisprs	cas6,DEDDh,csa3,cas3,Cas9_archaeal	0	0	0	0
NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	7 crisprs	cas7,csb2gr5,cas3,cas8u1,cas2,cas1,cas4,cas8b5,cas5,cas6,cas8c,cas7b,csa3	1	69	3	0

1. NC_017272

CRISPR-Cas detection and classification

Crispr_ID: NC_017272_1

• CRISPR_ID: NC_017272_1
• CRISPR_location: 537373-537480
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NC_017272_1

Consensus_repeat	Method
CGGGCCTCCGCCTGGAGGGGGAGG	CRISPRCasFinder

spacers of NC_017272_1

>1.1|537397|60|NC_017272|CRISPRCasFinder
GGGACGGGCCGTTGCGCTTGCGGCTTGTAGGGGAGGGGCTTGAGGCCGAGGCCCGGCTTT

CRISPR arrays and Neighbor proteins around NC_017272_1

CRISPR arrays

The CRISPR arrays of NC_017272_1

>merge|NC_017272|1|537373-537480|CRISPRCasFinder
CGGGCCTCCGCCTGGAGGGGGAGGGGGACGGGCCGTTGCGCTTGCGGCTTGTAGGGGAGGGGCTTGAGGCCGAGGCCCGGCTTTCGGGCCTCGGCCTGGAGGGGGAGG

>NC_017272|1|1|537373-537480|CRISPRCasFinder
CGGGCCTCCGCCTGGAGGGGGAGG	GGGACGGGCCGTTGCGCTTGCGGCTTGTAGGGGAGGGGCTTGAGGCCGAGGCCCGGCTTT
CGGGCCTCGGCCTGGAGGGGGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017272.1|WP_014510008.1|542618_543677_+|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl|CDD|369642
NC_017272.1|WP_008631894.1|523904_525095_+|thiolase-family-protein	unknown	unknown	gnl|CDD|238383
NC_017272.1|WP_008631899.1|530559_531012_+|DivIVA-domain-containing-protein	unknown	unknown	gnl|CDD|377456
NC_017272.1|WP_008631905.1|533190_533457_-|acylphosphatase	unknown	unknown	gnl|CDD|184679
NC_017272.1|WP_014510007.1|541547_542579_+|L-threonine-3-dehydrogenase	unknown	unknown	gnl|CDD|176184
NC_017272.1|WP_008631910.1|543662_544073_-|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl|CDD|223149
NC_017272.1|WP_008631900.1|530972_531518_-|YdcF-family-protein	unknown	unknown	gnl|CDD|99750
NC_017272.1|WP_008631916.1|549171_550872_-|hypothetical-protein	unknown	unknown	unknown
NC_017272.1|WP_014510012.1|547167_548220_+|hypothetical-protein	unknown	unknown	unknown
NC_017272.1|WP_008631895.1|525091_525400_-|DUF503-domain-containing-protein	unknown	unknown	gnl|CDD|377364
NC_017272.1|WP_014510011.1|546422_547166_+|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|176648
NC_017272.1|WP_081466123.1|531691_533203_+|GTPase-HflX	unknown	unknown	gnl|CDD|274455
NC_017272.1|WP_014510005.1|529915_530551_+|YggS-family-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|143483
NC_017272.1|WP_014510003.1|526509_528978_-|BamA/TamA-family-outer-membrane-protein	unknown	unknown	gnl|CDD|227116
NC_017272.1|WP_081466074.1|529023_529851_+|purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|350160
NC_017272.1|WP_014510009.1|544091_545000_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl|CDD|234626
NC_017272.1|WP_011172663.1|550868_551504_-|uridine-kinase	unknown	unknown	gnl|CDD|235492
NC_017272.1|WP_014509880.1|525416_525941_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_017272.1|WP_008631915.1|548197_549187_-|polysaccharide-pyruvyl-transferase-CsaB	unknown	unknown	gnl|CDD|132648
NC_017272.1|WP_014510010.1|545007_546423_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl|CDD|234572

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017272.1|WP_014510011.1|546422_547166_+|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	7.8e-38	124.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017272.1|WP_014510008.1|542618_543677_+|PQQ-dependent-sugar-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	2.66452e-123
NC_017272.1|WP_008631894.1|523904_525095_+|thiolase-family-protein	gnl|CDD|238383	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.	0
NC_017272.1|WP_008631899.1|530559_531012_+|DivIVA-domain-containing-protein	gnl|CDD|377456	pfam05103, DivIVA, DivIVA protein. The Bacillus subtilis divIVA1 mutation causes misplacement of the septum during cell division, resulting in the formation of small, circular, anucleate mini-cells. Inactivation of divIVA produces a mini-cell phenotype, whereas overproduction of DivIVA results in a filamentation phenotype. These proteins appear to contain coiled-coils.	3.69093e-32
NC_017272.1|WP_008631905.1|533190_533457_-|acylphosphatase	gnl|CDD|184679	PRK14433, PRK14433, acylphosphatase; Provisional.	1.84978e-48
NC_017272.1|WP_014510007.1|541547_542579_+|L-threonine-3-dehydrogenase	gnl|CDD|176184	cd05281, TDH, Threonine dehydrogenase. L-threonine dehydrogenase (TDH) catalyzes the zinc-dependent formation of 2-amino-3-ketobutyrate from L-threonine via NAD(H)- dependent oxidation. THD is a member of the zinc-requiring, medium chain NAD(H)-dependent alcohol dehydrogenase family (MDR). MDRs have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria) and have 2 tightly bound zinc atoms per subunit. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose.	0
NC_017272.1|WP_008631910.1|543662_544073_-|Hsp20/alpha-crystallin-family-protein	gnl|CDD|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	2.06567e-23
NC_017272.1|WP_008631900.1|530972_531518_-|YdcF-family-protein	gnl|CDD|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	5.44612e-42
NC_017272.1|WP_008631895.1|525091_525400_-|DUF503-domain-containing-protein	gnl|CDD|377364	pfam04456, DUF503, Protein of unknown function (DUF503). Family of hypothetical bacterial proteins.	1.85894e-24
NC_017272.1|WP_014510011.1|546422_547166_+|3'-5'-exonuclease	gnl|CDD|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	1.98296e-45
NC_017272.1|WP_081466123.1|531691_533203_+|GTPase-HflX	gnl|CDD|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	4.1553e-169
NC_017272.1|WP_014510005.1|529915_530551_+|YggS-family-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|143483	cd00635, PLPDE_III_YBL036c_like, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins. This family contains mostly uncharacterized proteins, widely distributed among eukaryotes, bacteria and archaea, that bear similarity to the yeast hypothetical protein YBL036c, which is homologous to a Pseudomonas aeruginosa gene that is co-transcribed with a known proline biosynthetic gene. YBL036c is a single domain monomeric protein with a typical TIM barrel fold. It binds the PLP cofactor and has been shown to exhibit amino acid racemase activity. The YBL036c structure is similar to the N-terminal domain of the fold type III PLP-dependent enzymes, bacterial alanine racemase and eukaryotic ornithine decarboxylase, which are two-domain dimeric proteins. The lack of a second domain in YBL036c may explain limited D- to L-alanine racemase or non-specific racemase activity.	3.38593e-97
NC_017272.1|WP_014510003.1|526509_528978_-|BamA/TamA-family-outer-membrane-protein	gnl|CDD|227116	COG4775, COG4775, Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane].	2.28526e-85
NC_017272.1|WP_081466074.1|529023_529851_+|purine-nucleoside-phosphorylase	gnl|CDD|350160	cd09009, PNP-EcPNPII_like, purine nucleoside phosphorylases similar to human PNP and Escherichia coli PNP-II (XapA). Human PNP catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. Patients with PNP deficiency typically present with severe immunodeficiency, neurological dysfunction, and autoimmunity. Escherichia coli PNPII, product of the xapA/pndA gene, catalyzes the phosphorolysis of xanthosine, inosine and guanosine with equal efficiency and has been referred to as xanthosine phosphorylase and inosine-guanosine phosphorylase. E. coli PNPII is also capable of converting nicotinamide to nicotinamide riboside, and may be involved in the NAD+ salvage pathway. It is one of two purine nucleoside phosphorylases found in E. coli, which also contains PNPI, which displays a different substrate specificity and belongs to a different subgroup of the nucleoside phosphorylase-I (NP-I) family than PNPII. NP-I family members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	5.94817e-151
NC_017272.1|WP_014510009.1|544091_545000_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl|CDD|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	5.62011e-131
NC_017272.1|WP_011172663.1|550868_551504_-|uridine-kinase	gnl|CDD|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	4.08695e-127
NC_017272.1|WP_014509880.1|525416_525941_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.69218e-17
NC_017272.1|WP_008631915.1|548197_549187_-|polysaccharide-pyruvyl-transferase-CsaB	gnl|CDD|132648	TIGR03609, S_layer_CsaB, polysaccharide pyruvyl transferase CsaB. The CsaB protein (cell surface anchoring B) of Bacillus anthracis adds a pyruvoyl group to peptidoglycan-associated polysaccharide. This addition is required for proteins with an S-layer homology domain (pfam00395) to bind. Within the larger group of proteins described by pfam04230, this model represents a distinct clade that nearly exactly follows the phylogenetic distribution of the S-layer homology domain (pfam00395). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	2.30228e-109
NC_017272.1|WP_014510010.1|545007_546423_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl|CDD|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0

Protein sequences

>NC_017272.1|WP_008631905.1|533190_533457_-|acylphosphatase
MPRLVALVKGRVQGVGYRAFAQKKALELGLSGYAENLPDGRVEVVAEGPKEALELFLHHLKQGPRLARVEAVEVQWGEEAGLKGFHVY
>NC_017272.1|WP_081466123.1|531691_533203_+|GTPase-HflX
MGRPLSLVLDREGRVVRVAVGDAKDVPFPEEGWSERRLSGYRLLHTHLGPGGLSRPDLSVLFLRRLDNLAALEVEADGRPGLLHLAFLSPPRALEEDWRVLPPKPFHQYLDLDLWGEVMALEEELSRQARVLEVRDGSGERALLVGVDTGEGPEAEAVLRELAELTRTAGGVPVKQILVFRKSLDPRYLVGLGKLEELKSLAYHENASTLIFGVDLTPAQAREIERVTGLKVLDRTQLILDIFALHAKTPEAQAQVELAQLRYLLPRLVGKGKEMSRLGGGIGTRGPGETKLEVDRRRLQDRIAHLSRKLQDYALRRKEARQKRKRRGVPLVAVVGYTNAGKTTLLRALTRAGEEGEDKLFATLRPLTRRGFLPGVGEVLFTDTVGFIRHMPEELLTAFRATLEEVREADVLVHVLDASEEGALERHRVVRDLLLDLGVEAPVVLALNKADRAAPYDLYFLGERLGGVPVSALKGTGLKELKEALARALLDLGVRPQAWAQYT
>NC_017272.1|WP_008631900.1|530972_531518_-|YdcF-family-protein
MGRVVLWLLLLALLPAYAQETYDWIVVLGAAQYGGRPSPALERRLEAALALYQRGLAPKIAVAGGKAKGDLWSEGEVGCRHLVARGVPEEALFCETRSRSTYENLLFLKPHLEGRLLLVTDAPHLPRALFLARLLGLEAEGYPVPGNYPLGYWAKEALYRLWLYLGLRPQGVFSSRFNASR
>NC_017272.1|WP_008631899.1|530559_531012_+|DivIVA-domain-containing-protein
MDLSPLDVRYQEFPRAFRGYHRGAVREYLARVAEAMEALIQENEALKERLRALEEENARLKEAEGELKRAVVAAERIARELKAQAEREAELLRKEAQAAKERLLQEAAQELKRLRAEIERARQEKALFLGQVRALFEGYLEALKRLEKTP
>NC_017272.1|WP_014510005.1|529915_530551_+|YggS-family-pyridoxal-phosphate-dependent-enzyme
MGLPQVLERIAQACRRAGRRPEEVRLVAVTKGRSVEEIREKVLAYGTFPLGESRVQEALKKMDLLQAEWHLVGHLQRNKAKFAPRFALVHSLDSLRLAEALEKVGEKAGVRLKVLVEVNLGREPQKHGVLEEELPELMARLGEMPHLEVLGLMTVPPIGPEGVVRPIFRRLSQLADRYGLPERSMGMSDDYEWAVEEGATLVRVGRALFVD
>NC_017272.1|WP_081466074.1|529023_529851_+|purine-nucleoside-phosphorylase
MPGMELYDKIQEAVAYVRSKTDFVPEVGLVLGSGLGPLADEVEKVAEIPYGEIPHFPVSTAPGHAGRLILGRLEGKPVLVYKGRVHYYEGYSAEEVVFPVRVGFFLGARTFLLTSAAGGLNPRFRAGGIMLHLDYINFAGANPLRGKNDERLGPRFPVMFEAYDPELIELARKVARRQDLHLFEGVYAWFMGPSFASRAELKLLRELGADAIGMSTVPEVIALRHLGARVLGLSTITDMAVPEREHHATEEEVLRVAAETGPVFRRYVRGILAAL
>NC_017272.1|WP_014510003.1|526509_528978_-|BamA/TamA-family-outer-membrane-protein
MKRLLALGLLALTALAAPLREIVVEGADPVLQALARAALPFGVGDEPQDLEAARRAILETGYFRDVRLALEGDVLKIVLVPNPPIAAVRVETEAFPEERLLAFLEQNFAIGKGATYNPVRAQEAAEALARAYRQAGFPFTPKVAVEAKEDKEGIALTFRVEERPEVKAVRLLGVSLLPEEELRKGLEALKGSFDFAKYQEALRAIAKRYEEAGYRFSGPDLQASALEEGVLTVQVRELKVARVEGEGLPLEGFPLKPKDPLNYQKLLEGIQDLSRKLSRVVNFTLLPQGDEVVVRLELGPEGGRIERVEVSGNTALPTEALLGLLRLKPGEVYTPALAQEDAARVAERYREEGYEVADVRYSFQDGVYRLEVVELKIGGYRLEWQGGHRTRDEVVLRELPKPGSLLNVQGLRKAIARLMATGLLAEPPRVSLAPGEKPDEAVVVLGLKEARTGLFQPAIGWSSLEGWSGSLAFKETNLFGLAHQVGLDLAFIQNDARDNLSFAAAYTVPWLYLDYLDLKEVRTSLAFSLYSTPIGNTKLLDGTTDTGWEYTERRTGASLSLSRPLSRDLSNLRTSLGLSLRRSAYLLEVYDPGAPCDTTGQDASRPCDPPGANTYKDPTYVRTLLPDAGWTLRLDTTLAYLDVDDPRFRTQGYEASLATGLGLSLPDAGGRSFFVPLVATGKTYVPLDAEKRQALAFRLSAGTLLGYPPESERFYLSGGGSEALLLRGYEDRKYGGLSFATASVEYRYDFRLSPQGGTNLYGILFTDLGLADNTGGVKWGAGIGIRLDLDVFGALLPSLRLDYAFSPESPTGRIHFRIGPMF
>NC_017272.1|WP_014509880.1|525416_525941_-|IS630-family-transposase
MRLLAYDEHRLGLKPVYRRVWARRGERPLAVGAHRYRWFYVCTFVEPETGESLSLLVDGIDTEVMGWVLRELRAWLGEGEEAWVVLDRAGWHVSGRVEVPEGVRLVFLPPYSPELQPVERVWPLVNEAVANRYFRDLEEMMEAVAERCRVLAQDPETLRRHTLFHWWPRTKELA
>NC_017272.1|WP_008631895.1|525091_525400_-|DUF503-domain-containing-protein
MKAYLGLYTARLETPARSLKEKRALIKPALERLKARFPVSAARLYGLDAWGYEVVGFTLLGNDPAWVEETMRAAARFLAEAGGFQVALEEFRLEAFELDGLI
>NC_017272.1|WP_008631894.1|523904_525095_+|thiolase-family-protein
MREVYVVAAVRTPIGKFGGVFKDVSPVDLGAHAMREALARAGVEGKALDLYVFGNVLRAGHGQLLPRQAALKAGIPKEVDGYQVDMVCASGMMAVLNAVQFLRTGEAHLVLAGGMESMSQAGFYLSHRARWGYKFLLGAPENLQDILLRDGLSDPFTGEAMGEQAERLAQDHGVTRQEIDEAAYLSHKRAAEATEKGLFAWEIAPMEVQGRKGPVVVDRDEGIRPETTLESLAALRPAFKKDGVLTAGNSSQISDGAAALLLASEEAVKAHGLKPLARVLGGAWAAGEPWRFPEAPIPAAKRLLDRLGMRVSDFGLFENNEAFALNNVLFSRLLDVPYERLNVFGGAVALGHPIGASGARILVTLLNALRAKGEERGLAAICHGTGGSVAFAVERV
>NC_017272.1|WP_014510007.1|541547_542579_+|L-threonine-3-dehydrogenase
MRALAKLAPEEGLTLVDRPVPEPGPGEVLVRVEAASICGTDLHIWKWDAWARGRIRPPLVTGHEFSGVVEAVGPGVKRPQVGDHVSLESHVVCHACPACRTGNYHVCLNTQILGVDRDGGFAEYVVVPAENAWVNPKDLPFEVAAILEPFGNAVHTVYAGSGVSGKSVLITGAGPIGLMAAMVARASGAGPILVSDPNPYRLAFARPYADRLVNPLEEDLLEVVRRVTGSGVEVLLEFSGSEAAIHQGLMALIPGGEARILGIPSDPIRFDLAGELVMRGITAFGIAGRRLWQTWMQGTALVYSGRVDLSPLITHRLPLSRYREAFGLLASGQAVKVILDPKA
>NC_017272.1|WP_014510008.1|542618_543677_+|PQQ-dependent-sugar-dehydrogenase
MDRRRFLVGLLGLGLARGQGLRVEEVVGGLEVPWALAFLPDGGMLISERPGRIRLFREDRLSTYAELSVYHRGESGLLGLALHPRFPQEPYVYAYRTVAEGGLRNQVVRLRHLGERGVLDRVVLDGIPARPHGLHSGGRIAFGPDGMLYVTTGEVYERELAQDLASLGGKILRLTPEGEPAPRNPFLGRRGARPEVYSLGHRNPQGLAWHPRTGELFSSEHGPSGELGYGHDEVNLIVPGGNYGWPRVVGRGNDPRYRDPLYVWPQGFPPGNLAFFRGDLYVAGLRGQALLRLVLEGERGRWRVLRVETALSGFGRLREVQVGPDGALYVTTSNRDGRGQVRPGDDRVLRLL
>NC_017272.1|WP_008631910.1|543662_544073_-|Hsp20/alpha-crystallin-family-protein
MLERRDRLETLRKLKELQERIAELAYLLTGEEPAAWTPRVDLLETEEHYVLLVDLPGVRPEDLELLEEGQRVTLAGVRHPLPGTYLLEERPMGTFRRTLDLPGPIEEGTAQATLRNGVLEVRFRKKPATALPLKEA
>NC_017272.1|WP_014510009.1|544091_545000_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MEAIPVLAGPTGSGKTFLALRLGEEVPVEVVSADATMVYRGLDIGTDKPTPEERARVPHHLVDVLEPHEAMSVARFLALAEEAIAHVLSRGKLPLVVGGTGYYIRALSEGLHDLPPPDPGVQEALWAELEARGLEALLAELARASPEDARRVGKNPRRLVRALEVLRRTGTPPARFPKRPPRFRYKKLVLWPDRAWLFPRLEERAKAQFARGLVEEVRGLLARYPRMPTALQAIGYKEVAGHLLGEYGLEEALERDIRAVKAYAKRQYTWFRHEPGDVVYLPRGGEEAYVGFRDWLRLHFGL
>NC_017272.1|WP_014510010.1|545007_546423_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MLAHEIRARVARGEVSPREVAQAYLKRVQELDPGLGAFLSLNERLLEEAEGVDPGLPLAGLVVAVKDNIATRGLRTTAGSRLLENFVPPYEATAVGRLRALGALVLGKTNLDEFGMGSSTEHSAFFPTKNPFDPHRVPGGSSGGSAAALAADLAPLALGSDTGGSVRQPAAFCGVYGLKPTYGRVSRFGLIAYASSLDQIGPMARSVRDLALLMDAMAGPDPLDATSLDLPPRFQEALEGPLPPLRLGVVREALAGNSPGVERALEEALKVFRELGLSVREVSWPSLPQALAAYYILAPAEASSNLARYDGTLYGRRAEGEEVEGMMEATRALFGLEVKRRVLVGTFVLSSGYYEAYYGRAQAFRRRLKAEAQALFREVDLLLLPTTPHPAFPFGARRDPLAMYREDLYTVGANLTGLPALSFPAGFEGHLPVGLQLLAPWGEDERLLRAALAFEEATARAHLRAPLGEAL
>NC_017272.1|WP_014510011.1|546422_547166_+|3'-5'-exonuclease
MEAAFRYRMATRLARRLREAGRPLPLPALGEALGLRGPVERVVRPLLDGRFLLEEAVGLWEWRYPFPLEGEAVVVLDLETTGLAPGLDEVIEVGLLRLEGGRRLPFQSLVRPSRPPSPFVERLTGIPREALEEAPSLEEVLEKAYPLLADATLVIHNAAFDLGFLRPALEGLGYRLENPVVDSLRLARRGLPGLRRYGLDALSEVLELPRRTCHRALEDVERTLAVVHEVYYMLTSGRPRTLWELGR
>NC_017272.1|WP_014510012.1|547167_548220_+|hypothetical-protein
MTARYVLTSACIQTGTMALTVSLRQRLLGREQVRFVDEDGEAYTVEVDWKAGVLRGLGPYYQKRRLSANETVLLLFRGEEVELKAAPRPGQRPPAREREARPEETSPPPEPQKRRVRVAPYPKEVLFPHEPLEPPGATEDLRRLGFQLEEGPPWVYRAFSGRRRLTLVLLRLGEGEVERLKPYRLQGAYTALLAPESQRDRVPEGVGFVSPEALTRLARLKGRFPLTPWDLEDLLKEGRVDLEAVEALEDRLAAELSERGAFAALLLLLARKPLGEVFLLADLEAEALEEGLVPEVVRQGVEVLAQPPFLLLKRLSPGEFLLRQSVEEALEDLRAFAEGLAGRLSRARSL
>NC_017272.1|WP_008631915.1|548197_549187_-|polysaccharide-pyruvyl-transferase-CsaB
MVVGVAGYYGFRNAGDEAILEAIARELKARGHEVVALSGDPKRTREDHGLKAYHRLNPLALLRADLWLLGGGGLLQDATSALSLTYYLSVLRLARLFRKRVVVFNQSLGPLSPWGERRVQKALKGVPVILRDQDSLEYARRLGIPAALGADPALLLPPPPVPREEDLVLVIPRAGVREEALTTLYVAANHLVHEGKQVLVLLLQPGYDDEVAEVFRLHRIERTSDPRRLLYLAAQAGYVISMRLHGLILAAAAGTPFAALSYDPKVAAFAKETGAYYQELPGEPIKLYKAALYGRFPDWEKVARLKERARKSFDLALGEGVPIKGSGRG
>NC_017272.1|WP_008631916.1|549171_550872_-|hypothetical-protein
MRAFLHLLLFLALLPSLFALAPRLRAQAPGPVALVLDAEAVREEARARGEDLMAALARYQALGVNGVAFPERLVRDWVGEGVLLYRQGRELVEMGLSARPGWHYLKGDPALLALLERAYDLPSERLGEWLGFPVDVQALPAFYNLEELRQAKAMGLYVMVRPLNHRLRRLEAGLPLVPKEADAVVFLGLEALGYPYRLGEAKALVPVPVALIEGTPQAGLGAFRDKGILRLFSLRYEWLLTLKPEEAAEKYGLAARERSHQILYLRPYPYPEDTARLLKRLQEELKASGLPLGAPSPRALAPSPLRYAAWVGVLAGLGLLALGLPVYGPLVAFLLLLFALGYAGSQAGPLLAALVFPVLGFLGPRNGLWMWARSLGYALLGAVFLSALGSTEEALSGLAPFKGVSLTLLVPPLLVAYSFLEKNFKEALTRLFLHPVRLGEVALGGLALGLLLLALLRRGNDAPIVPELELKLRALLQDVMVRPRFKEVFGHALFPLALLLPWPRWVQNGLLFLASLGIASILNTFSHYHTPLPISFFRVLNGALLGLSLGLVGVILVRRLRAWWSA
>NC_017272.1|WP_011172663.1|550868_551504_-|uridine-kinase
MSAPKPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYDHPDAFDLALYLEHAQALLRGLPVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKELRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQYLEQVKPMHLHFVEPTKRYADVIVPRGGQNPVALEMLAAKALARLARMGAA

Crispr_ID: NC_017272_2

• CRISPR_ID: NC_017272_2
• CRISPR_location: 1543969-1544074
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017272_2

Consensus_repeat	Method
CCAGGGCCGCCTGGGCGAGGAGGA	CRISPRCasFinder

spacers of NC_017272_2

>2.1|1543993|58|NC_017272|CRISPRCasFinder
GGAGGCCCGCGAGCCACCGCATCCTTACCCTAGAACCCCCGTTCGGCGGAGATCAGGG

CRISPR arrays and Neighbor proteins around NC_017272_2

CRISPR arrays

The CRISPR arrays of NC_017272_2

>merge|NC_017272|2|1543969-1544074|CRISPRCasFinder
CCAGGGCCGCCTGGGCGAGGAGGAGGAGGCCCGCGAGCCACCGCATCCTTACCCTAGAACCCCCGTTCGGCGGAGATCAGGGCCAGCGCCGCCTGGGCGAGGAGGA

>NC_017272|2|2|1543969-1544074|CRISPRCasFinder
CCAGGGCCGCCTGGGCGAGGAGGA	GGAGGCCCGCGAGCCACCGCATCCTTACCCTAGAACCCCCGTTCGGCGGAGATCAGGG
CCAGCGCCGCCTGGGCGAGGAGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017272.1|WP_008633212.1|1536462_1537650_+|glycine-C-acetyltransferase	unknown	unknown	gnl|CDD|130884
NC_017272.1|WP_014510734.1|1535479_1536367_-|DUF4032-domain-containing-protein	unknown	unknown	gnl|CDD|379077
NC_017272.1|WP_014510737.1|1539375_1541280_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl|CDD|235542
NC_017272.1|WP_011173641.1|1553362_1553746_+|hypothetical-protein	unknown	unknown	gnl|CDD|224929
NC_017272.1|WP_014510738.1|1541327_1542287_-|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234993
NC_017272.1|WP_014510736.1|1538852_1539236_-|hypothetical-protein	unknown	unknown	unknown
NC_017272.1|WP_014510741.1|1544628_1545933_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_017272.1|WP_081466108.1|1548506_1549271_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NC_017272.1|WP_011173631.1|1542863_1543484_-|50S-ribosomal-protein-L25	unknown	unknown	gnl|CDD|235534
NC_017272.1|WP_008633233.1|1552775_1553360_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NC_017272.1|WP_014510733.1|1534731_1535421_+|transposase	unknown	unknown	gnl|CDD|376573
NC_017272.1|WP_008633218.1|1542296_1542848_-|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|235457
NC_017272.1|WP_041444918.1|1546548_1548507_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_017272.1|WP_014510742.1|1545901_1546552_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_017272.1|WP_014510735.1|1537651_1538866_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|378996
NC_017272.1|WP_081466109.1|1551446_1552445_-|porphobilinogen-synthase	unknown	unknown	gnl|CDD|236450
NC_017272.1|WP_155983627.1|1534372_1534489_-|hypothetical-protein	unknown	unknown	unknown
NC_017272.1|WP_008633232.1|1552457_1552775_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
NC_017272.1|WP_011173642.1|1553733_1554075_+|hypothetical-protein	unknown	unknown	gnl|CDD|214939
NC_017272.1|WP_014510745.1|1549288_1551004_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017272.1|WP_008633212.1|1536462_1537650_+|glycine-C-acetyltransferase	gnl|CDD|130884	TIGR01825, 8-amino-7-oxononanoate_synthase_1, pyridoxal phosphate-dependent acyltransferase, putative. This model represents an enzyme subfamily related to three known enzymes; it appears closest to glycine C-acteyltransferase, shows no overlap with it in species distribution, and may share that function. The three closely related enzymes are glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase), 5-aminolevulinic acid synthase, and 8-amino-7-oxononanoate synthase. All transfer the R-group (acetyl, succinyl, or 6-carboxyhexanoyl) from coenzyme A to an amino acid (Gly, Gly, Ala, respectively), with release of CO2 for the latter two reactions.	0
NC_017272.1|WP_014510734.1|1535479_1536367_-|DUF4032-domain-containing-protein	gnl|CDD|379077	pfam13224, DUF4032, Domain of unknown function (DUF4032). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is approximately 170 amino acids in length. The family is found in association with pfam06293.	5.05831e-08
NC_017272.1|WP_014510737.1|1539375_1541280_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl|CDD|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0
NC_017272.1|WP_011173641.1|1553362_1553746_+|hypothetical-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	1.6697e-09
NC_017272.1|WP_014510738.1|1541327_1542287_-|D-alanine--D-alanine-ligase	gnl|CDD|234993	PRK01966, ddl, D-alanine--D-alanine ligase.	2.00403e-159
NC_017272.1|WP_014510733.1|1534731_1535421_+|transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	0.000417239
NC_017272.1|WP_014510741.1|1544628_1545933_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.28043e-38
NC_017272.1|WP_081466108.1|1548506_1549271_-|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	2.85027e-58
NC_017272.1|WP_014510742.1|1545901_1546552_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.88086e-64
NC_017272.1|WP_008633233.1|1552775_1553360_+|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	4.42001e-106
NC_017272.1|WP_008633218.1|1542296_1542848_-|aminoacyl-tRNA-hydrolase	gnl|CDD|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	4.37512e-87
NC_017272.1|WP_041444918.1|1546548_1548507_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.06973e-107
NC_017272.1|WP_011173631.1|1542863_1543484_-|50S-ribosomal-protein-L25	gnl|CDD|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	4.0154e-58
NC_017272.1|WP_014510735.1|1537651_1538866_+|SAM-dependent-methyltransferase	gnl|CDD|378996	pfam12950, TaqI_C, TaqI-like C-terminal specificity domain. This domain is found at the C-terminus of the TaqI protein and is involved in DNA-binding and substrate recognition.	2.55005e-17
NC_017272.1|WP_081466109.1|1551446_1552445_-|porphobilinogen-synthase	gnl|CDD|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NC_017272.1|WP_011173642.1|1553733_1554075_+|hypothetical-protein	gnl|CDD|214939	smart00960, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	3.26848e-08
NC_017272.1|WP_008633232.1|1552457_1552775_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	5.28342e-22

Protein sequences

>NC_017272.1|WP_011173631.1|1542863_1543484_-|50S-ribosomal-protein-L25
MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYVPLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSLHASDLKLPPGVELAVSPEETIAAVVPPEDVEKLAEEAAAEVAEPEVIKKGKEEEEE
>NC_017272.1|WP_008633218.1|1542296_1542848_-|aminoacyl-tRNA-hydrolase
MFLVVGQGNPGERYARTRHNLGFMVLDRLGLSFRPRGEALVAEAEGGFFLKPLTYYNLTGRAVAPLARFYKIPPERILVVHDEMDLPLGRIRFKAGGSAAGNRGVLSIEEALGTRAFHRLRLGIGKPPDPSRGAEYVLSPFREEELPVVERVLEAAKEAVWCWVREGLPPCAGRFNGLDLSLG
>NC_017272.1|WP_014510738.1|1541327_1542287_-|D-alanine--D-alanine-ligase
MRVLLIAGGVSPEHEVSLLSAEGVLRHMPFPTDLAVIARDGRWLFGEKALAALEAKAAPEGEHPFPPPLPWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVTASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPMVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT
>NC_017272.1|WP_014510737.1|1539375_1541280_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MSYDASAIRVLKGLEGVRHRPAMYIGGTGVEGYHHLFKEILDNAVDEALAGYATEILVRLNEDGSLTVEDNGRGIPVDLMPEEGKPAVEVIYTTLHSGGKFEQGAYKVSGGLHGVGASVVNALSEWTVVEVFREGKHHRIAFSRGEVTEPLRVVGEAPRGKTGTRVTFKPDPEIFGNLRFDPSEIRARLREVAYLVAGLKLVFQDRQHGKEEVFLDKGGVASFAKALAEGEDLLYEKPFLIRGTHGEVEVEVGFLHTQGYNAEILTYANMIPTRDGGTHLTAFKSAYSRALNQYAKKAGLNKEKGPQPTGDDLLEGLYAVVSVKLPNPQFEGQTKGKLLNPEAGTAVGQVVYERLLEILEENPRIAKAVYEKALRAAQAREAARKARELVRRQNPLESDELPGKLADCQTENPEEAELFIVEGDSAGGSAKQGRDRRFQAILPLRGKILNVEKAGLSKALKNAEVRAMVSAIGVGIGGDGEAHFDLEGLRYHKIIIMTDADVDGSHIRTLLLTFFYRYMRPLIERGHVYIAQPPLYRLQVGRKVEYLYSDEELQARLKELEGKSYEVQRFKGLGEMNPEQLWETTMNPEKRVLKRVELQDALEASELFEKLMGQEVAPRREFIEEHARYAELDI
>NC_017272.1|WP_014510736.1|1538852_1539236_-|hypothetical-protein
MVGVFLHASLGLFLLVAVPALALVGLFGFFRPLPSRFYAFLRGVAWVAILQVLLGFLLFLQGLRPKDGLHLLYGLLLAAGLHYLGGLEPGGWFYRGLKDPPKRPEVFVALGLLFCVGLVLRVYLTGR
>NC_017272.1|WP_014510735.1|1537651_1538866_+|SAM-dependent-methyltransferase
MLFPPSLPPTPSGRSLGRVETPPGLVRFMVGLAEAPKGGRVLEPACADGPFLRAFREAHGTGYRFVGVEIDPHALDLPPWAEGVVADFLLWEPGEAFDLILGNPPYGALGAGARLPAPLRAAYRRNFATWRGRYNLYGAFLEKGVRLLREGGTLCFVVPAGWMVLEEFAFLRAFLAREGALEVYYLGRAFPGLKVRATVLRFRKGGRGLRLYDAEGKPPELLLEDPLWQGKMVRFPHPEALALEREGLPMGRLFRLHFAARSPEVRAHPLTQKAPGPGLVPVLTGRNLLPGRIDYETPYSGLYFPQAEVHRLKPFYAFPRLVVGHTRHYRVVAAWDGQAYPWREEFHLLPKEGVRVDWEGVVAYLNGPLAQAYYRGLYREVVPHLTRVMLERFPLPRDLVLTGP
>NC_017272.1|WP_008633212.1|1536462_1537650_+|glycine-C-acetyltransferase
MNLDLRARVREELERLKREGLYISPKVLEAPQEPVTRVEGREVVNLASNNYLGFANHPYLKEKARQYLEKWGVGSGAVRTIAGTFTYHLELEEALARFKGTESALVLQSGFTANQGVLGALLKEGDVVFSDELNHASIIDGLRLTKATRLVYRHADVAHLEELLRTHDTEGLKLIVTDGVFSMDGDIAPLDRIVPLAKRYGAVVYVDDAHGSGVLGEKGKGTVHHFGFHQDPDVVQVATLSKAWAGIGGYAAGARELKDLLINKARPFLFSTSHPPAVVGALLGALELIQKEPERVERLWENTRYFKRELARLGYDTLGSQTPITPVLFGEAPLAFEASRLLLEEGVFAVGIGFPTVPRGKARIRNIVTAAHTKEMLDKALEAYAKVGRRLGIIR
>NC_017272.1|WP_014510734.1|1535479_1536367_-|DUF4032-domain-containing-protein
MRAELQAETEAERLERRAKLHELLHRLRGEPNVLLPFHQALALRPKGEHPLGLRTIEVDKVVGSVDRYEDFDHHFLPKTPHTLERWKRLRALQLSGVEFPPIEVYQVGEAYFVKDGNHRVALAKATGQKYIDAYVIALDVPVPVGAKDTLKDLILKAEYANFLEKTRLKELVPEAEDILFSTLGRYDILLDHIATRRYFKGLEENREIPWEEAVVDWYENLYKPTVEAIRRLGLLREFPGRTEADLYLWVMDHRYFLAQELGADLGPEEAARSYEARFGPWWKRLGGWLKKAILG
>NC_017272.1|WP_014510733.1|1534731_1535421_+|transposase
MRPSWRGFPGNWRPISSRSPRRKAKRLRTRRRHTWRRFPPLYLMDTTGLAYRSKDRFLRFRRGKEVRRVRGHARLLALMRWDRERRLLWPWGGVVGEGYAPDPRLGGEVLKRFPPSRGWLLADAGFDGKEVWGVLGEAGVRPVIRLRGGGEAREEARVRAREGWDPEVYRFRGVVEGVFGGMKTRLGGGYLWERKPWTAMARAFLELIAYGLRVLLSLLPPPPGYKAIY
>NC_017272.1|WP_155983627.1|1534372_1534489_-|hypothetical-protein
MGLASLRRKPRLSIRREIYTRPPDLCKASPVQINKAKT
>NC_017272.1|WP_014510741.1|1544628_1545933_-|HAMP-domain-containing-histidine-kinase
MATAFSSLRARLFALLLLALFLLLAPLAWLSAREAERAASEDLRRALYTRLYLLQAEGIQDEERLLLELFRLAQLFGGGVGFVLREGEARFTQLGDWPLPPGLPAALAAEGVYQGVFRGTLYVALAQEGLAYGLAVPLEGVSGLGRRLLARYALWGGGLLLGVFLLAALALSWALRPLRDLEKALRARVPEDLSPLPDPGLAELRPVVAALNALFARVGRLLAELAEKEEAARRFARHASHELRTPLTALKGYLEVLRRKDEPRALEGALREAGRMEALLAGLLRLSRLEALPPQRVPLDLRAFLEAQGLEVQGEGRVLADPELLALAVENVLENARRHGRLPVRAELSREGEGVWVWLVDAGPGFPEDLLPRVLEPFVHGGKGTGLGLALVAAVARAHGGRVRVENRGGAGVGLYLPLAPLKVSPGAPFGEGG
>NC_017272.1|WP_014510742.1|1545901_1546552_-|response-regulator-transcription-factor
MRVLLVEDDPGVREALELGLSLEGHEVRAVDRPEEALGLLSWAEVVILDVLLPRGDGFSLLRAIRERSEVPVLMLTALDGVEWRVKGLREGADDYLVKPYSLQELLARLEALVRRARRREEVLAYKDLRLYPRRMEAFRGERRLALSPKAFLLLKAFLEAPEEVLSKEALMRKVWGEEVEPATLEVHLSALRKALGEPSPIQTVRGYGYRLFLPEG
>NC_017272.1|WP_041444918.1|1546548_1548507_-|protein-kinase
MALLLAALLVLLTALLAVRLPAWASALLLGLLAGSGYALGVRSEALPAGALLLLGALAAPRLYLGPRRRKRPERRPPGPKRPAAAGTTAEREALSQRYEILEKVGLGGMATVYKAKDRKTGRLVALKVPQERFLGDPRFVRRFHREAEVLTRMDHPNIVKVYDHGQVEGVHYIAMEFLDGEGLDKLIEERRLSLRQAAAILARVADALKHIHAQGIVHRDIKPGNIMVLKGALREDGVDPRGVRLMDFGIAAGRVLTRLTITGARIGTPVYMSPEQAKGQKLDHRSDIYSLGIVLYEALTGQPPFTGGYETVIHQQIFQMPTPPKQLRPEIPQALSDLVLRMLEKDPAKRPGLDEVVRVLEGPWEEEDELSEAQYLLVAVEAKKGAVRLLDLEGTPARLLFGVGSGAGQFPSPPLAVAADPEGGIWVAVFQHGERLVHRLSPQGEVLLSTGPYGMKPGEFLLPVGLAVLEDQVFVLDGETATVSRLDLAGRYQGRFGGQGLGRGTFQDPKALVAAEGHLFVLDYGNRQVQRLTPEGEYLSRYAFRRSREDGALRLLGGVGAGEGRLYLYDVEAVKVRVLDLSGRLLASYPLPLLEGEDRMSLVELLPVGRILYAARRGSSRIHRISLDTGEALPPLEVYAPVRGLALWRRTP
>NC_017272.1|WP_081466108.1|1548506_1549271_-|serine/threonine-protein-phosphatase
MEPMRIAPRLSVAAVSHVGRRQNNEDFHRVLPLETPAGLLLLLAVADGMGGLEAGEWASKLAIEALSEAARGYAEHLQSGRPAVGLARVMEKGFLLARRRVEREAERPGRRGMGTTLTAFLYADWIKEGVVGHIGDSRAYRFGPTGVFRLTEDHSWVAERVKEGVLTRTEAERHPYRNVLTRALGLPEARFDLVEVRLAPGEGVLLVTDGLYGHVPEEEWRLGRDLQASLEAMVAEALRRGGDDNVTAVALRVE
>NC_017272.1|WP_014510745.1|1549288_1551004_+|hypothetical-protein
MDHLDDLVDLYEYRVEDLLQGRTPKGGKQALLRLRQLLIQSRLPGPLAKRFRQADARFRAQRRAPAPEAEAPVELPTIAVPEEPEPPPPEASPLAALALKVWRLQVERDVKARLEALLAGRREELRLIHAFLDNFALYRETPGFKRDFNLSRFVPTRPIPSLSDTLVDLDDPKVAQALVVDFLETARELPKLLPLPPEETRTYVRRFLNRLLEWEGAYNLPPKPDLLALRRALEEARRLGAGEKEVAQLEERLRKAAQEARRRELLLEEEKGRFRVALEKVVALLSLLPTPQGETPWPRVPEPGQEEEGLLTLRLAPGPVVLGPLTLTLSHAGGTWYLGLEGEDHPLEDTFVLPWEDLEVWAVRENDLLHLRLEARSGLRLYELLAEGRLLAYLLHPGKDYAYLRLLRGLSARLKGEFQAQAFGPALAEKYRKAPEEALQDFARKGLDLTLKRLGQADPLPLLQEVGKALGLEAEAQTLGQGLREYLGRRPPTRETLGGEVHFLALTPEPQALKVDQHALSVRLEEDAVYLGQAGEVPRRLKDLLVYRLGGKALILAREGRRLAYTLLPLP
>NC_017272.1|WP_081466109.1|1551446_1552445_-|porphobilinogen-synthase
MSIVEGMERPRRLRSPLLRPLVAEVELSPKHLILPLFVKEGGEMEEVSSMPGVFRHPLSGLPRVAEEALKAGLGGVILFGVLPQEAKDPLGKGAYAEDGVVQRAIRLLKQEFPELLVVADTCLCEYTDHGHCGVVKEGPLGFYVDNDATLDLLARTALSQAQAGADVVAPSAMMDGQVKAIREALDRGGFAHVPILSYAVKYASAFYGPFREAAQSAPGFGDRSGYQMDPRAGLWDALREAALDDLEGADMLMVKPALPYLDVLSALKGRFAKPLFAYQVSGEYAMLKAAVLKGWLDERRAVLESLFALRRAGAQGILTYYALEAARWLKEA
>NC_017272.1|WP_008633232.1|1552457_1552775_+|YbaB/EbfC-family-nucleoid-associated-protein
MNFQKLLKEAQKAQKKAAEVQERLERMTVVGSAQGLVEVEANGHGKILALRLKPEALKAFQDDPEGLEDLLLVAIQDAQTKAHELSEKEMAKELGGVGQMLGKLF
>NC_017272.1|WP_008633233.1|1552775_1553360_+|recombination-protein-RecR
MRYPESLLKLTRALSRLPGIGPKTAQRLALHLAFHKEEAEALAEALEGLKRVRACRECGNLAEGELCPICQDEDRDRSLLAVVESVADLYALERSGEFRGLYHVLGGALNPLEGIGPKELNLEGLFRRLEGVEEVVLATSMTVEGEATALYLAEELKKRGVRVTRPAYGLPVGGSLEYADEVTLGRALEGRRPV
>NC_017272.1|WP_011173641.1|1553362_1553746_+|hypothetical-protein
MRIGPELLQDLLDQVEGSLAAAIGTPDGLLVEGVRKRPLDLEAAIAEHAALWRQARAAYARSLGAEEVGELLVGGTGVVGYLRSMRTRDPEPLFLLLLLTPEANLGQARLAARRLLDRAGGVVAWPT
>NC_017272.1|WP_011173642.1|1553733_1554075_+|hypothetical-protein
MAYLTGLSALGVDQAVFTGMDGLVIEALGQGPPSAEALAAELAALARRMDPLAQALGGKVLRFTLATEDREVLAVRVGEFLLGAVVHRGLNRKAVGQELSRIALRLEEAWREG

2. NC_017273

CRISPR-Cas detection and classification

Crispr_ID: NC_017273_1

• CRISPR_ID: NC_017273_1
• CRISPR_location: 102879-103876
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 13 spacers
• Cas_protein_info: cas8u1,cas3,csb2gr5,cas7

Consensus repeat of NC_017273_1

Consensus_repeat	Method
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CRISPRCasFinder
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CRT
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	PILER-CR

spacers of NC_017273_1

>1.1|102916|38|NC_017273|CRISPRCasFinder,CRT
TGGCCCGGGAGCAACGTGGACCTCATCCGGGAGAAGTA
>1.2|102991|36|NC_017273|CRISPRCasFinder,CRT
CTCACCAACGGGGACGTACAGGAGGGGGACCTCCTC
>1.3|103064|38|NC_017273|CRISPRCasFinder,CRT
AGCGCCTTCGGCGGCGAGGAAATGTGCCCGGCGTGCAA
>1.4|103139|35|NC_017273|CRISPRCasFinder,CRT
CGCTCTCGACTTCGACCGCCTCACCGGCATCGGGG
>1.5|103211|38|NC_017273|CRISPRCasFinder,CRT
AAGGTTCTGGAGGCCCACAGCCTGGAGTGCATTCCCTA
>1.6|103286|38|NC_017273|CRISPRCasFinder,CRT
TGGCCGATGCGGTGAACGTTTACAGGGGCGCGCAGGCC
>1.7|103361|37|NC_017273|CRISPRCasFinder,CRT
GTCTTCCTCGACCCCCCGTACCGGGGCTACGAGGACG
>1.8|103435|36|NC_017273|CRISPRCasFinder,CRT
AGGTTCGGGCAAGAGGTGGCCGACTACGTGGAGGCC
>1.9|103508|38|NC_017273|CRISPRCasFinder,CRT
GTTTGCGGGGGGGTATGGGGTTTGGGGGGTGAGCCCCG
>1.10|103583|36|NC_017273|CRISPRCasFinder,CRT
CCCGAGGAGGCCCTGCACGACCTCATGGTCTGGGCC
>1.11|103656|38|NC_017273|CRISPRCasFinder,CRT
TGCCCCAGTATGGCGATGGTCATGGCCCGGTCCGCCCA
>1.12|103731|35|NC_017273|CRISPRCasFinder,CRT
CAGGTCATGGGAATGTCGTAGTGGACCAGCCACTC
>1.13|103803|37|NC_017273|CRISPRCasFinder,CRT
CCCACGGCGGCTAGGGCCTCCCTAGCCCGCCCCAGTT
>1.14|102916|42|NC_017273|PILER-CR
TGGCCCGGGAGCAACGTGGACCTCATCCGGGAGAAGTAGTTG
>1.15|102991|40|NC_017273|PILER-CR
CTCACCAACGGGGACGTACAGGAGGGGGACCTCCTCGTTG
>1.16|103064|42|NC_017273|PILER-CR
AGCGCCTTCGGCGGCGAGGAAATGTGCCCGGCGTGCAAGTTG
>1.17|103139|39|NC_017273|PILER-CR
CGCTCTCGACTTCGACCGCCTCACCGGCATCGGGGGTTG
>1.18|103211|42|NC_017273|PILER-CR
AAGGTTCTGGAGGCCCACAGCCTGGAGTGCATTCCCTAGTTG
>1.19|103286|42|NC_017273|PILER-CR
TGGCCGATGCGGTGAACGTTTACAGGGGCGCGCAGGCCGTTG
>1.20|103361|41|NC_017273|PILER-CR
GTCTTCCTCGACCCCCCGTACCGGGGCTACGAGGACGGTTG
>1.21|103435|40|NC_017273|PILER-CR
AGGTTCGGGCAAGAGGTGGCCGACTACGTGGAGGCCGTTG
>1.22|103508|42|NC_017273|PILER-CR
GTTTGCGGGGGGGTATGGGGTTTGGGGGGTGAGCCCCGGTTG
>1.23|103583|40|NC_017273|PILER-CR
CCCGAGGAGGCCCTGCACGACCTCATGGTCTGGGCCGTTG
>1.24|103656|42|NC_017273|PILER-CR
TGCCCCAGTATGGCGATGGTCATGGCCCGGTCCGCCCAGTTG
>1.25|103731|39|NC_017273|PILER-CR
CAGGTCATGGGAATGTCGTAGTGGACCAGCCACTCGTTG
>1.26|103803|41|NC_017273|PILER-CR
CCCACGGCGGCTAGGGCCTCCCTAGCCCGCCCCAGTTGTTA

CRISPR arrays and Neighbor proteins around NC_017273_1

CRISPR arrays

The CRISPR arrays of NC_017273_1

>merge|NC_017273|1|102879-103876|CRISPRCasFinder,CRT,PILER-CR
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGTGGCCCGGGAGCAACGTGGACCTCATCCGGGAGAAGTAGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGCTCACCAACGGGGACGTACAGGAGGGGGACCTCCTCGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGAGCGCCTTCGGCGGCGAGGAAATGTGCCCGGCGTGCAAGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGCGCTCTCGACTTCGACCGCCTCACCGGCATCGGGGGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGAAGGTTCTGGAGGCCCACAGCCTGGAGTGCATTCCCTAGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGTGGCCGATGCGGTGAACGTTTACAGGGGCGCGCAGGCCGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGGTCTTCCTCGACCCCCCGTACCGGGGCTACGAGGACGGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGAGGTTCGGGCAAGAGGTGGCCGACTACGTGGAGGCCGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGGTTTGCGGGGGGGTATGGGGTTTGGGGGGTGAGCCCCGGTTGCATCCAAGCTTCACAGCTTGGTTACGTTGCAGGCCCGAGGAGGCCCTGCACGACCTCATGGTCTGGGCCGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGTGCCCCAGTATGGCGATGGTCATGGCCCGGTCCGCCCAGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGCAGGTCATGGGAATGTCGTAGTGGACCAGCCACTCGTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGGCCCACGGCGGCTAGGGCCTCCCTAGCCCGCCCCAGTTGTTACATCCAAGCTTCACAGCTTGGCTACGTTGCAGG

>NC_017273|1|1|102879-103876|CRISPRCasFinder
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGGCCCGGGAGCAACGTGGACCTCATCCGGGAGAAGTA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CTCACCAACGGGGACGTACAGGAGGGGGACCTCCTC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AGCGCCTTCGGCGGCGAGGAAATGTGCCCGGCGTGCAA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CGCTCTCGACTTCGACCGCCTCACCGGCATCGGGG
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AAGGTTCTGGAGGCCCACAGCCTGGAGTGCATTCCCTA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGGCCGATGCGGTGAACGTTTACAGGGGCGCGCAGGCC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	GTCTTCCTCGACCCCCCGTACCGGGGCTACGAGGACG
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AGGTTCGGGCAAGAGGTGGCCGACTACGTGGAGGCC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	GTTTGCGGGGGGGTATGGGGTTTGGGGGGTGAGCCCCG
GTTGCATCCAAGCTTCACAGCTTGGTTACGTTGCAGG	CCCGAGGAGGCCCTGCACGACCTCATGGTCTGGGCC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGCCCCAGTATGGCGATGGTCATGGCCCGGTCCGCCCA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CAGGTCATGGGAATGTCGTAGTGGACCAGCCACTC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CCCACGGCGGCTAGGGCCTCCCTAGCCCGCCCCAGTT
GTTACATCCAAGCTTCACAGCTTGGCTACGTTGCAGG

>NC_017273|1|1|102879-103876|CRT
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGGCCCGGGAGCAACGTGGACCTCATCCGGGAGAAGTA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CTCACCAACGGGGACGTACAGGAGGGGGACCTCCTC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AGCGCCTTCGGCGGCGAGGAAATGTGCCCGGCGTGCAA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CGCTCTCGACTTCGACCGCCTCACCGGCATCGGGG
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AAGGTTCTGGAGGCCCACAGCCTGGAGTGCATTCCCTA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGGCCGATGCGGTGAACGTTTACAGGGGCGCGCAGGCC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	GTCTTCCTCGACCCCCCGTACCGGGGCTACGAGGACG
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AGGTTCGGGCAAGAGGTGGCCGACTACGTGGAGGCC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	GTTTGCGGGGGGGTATGGGGTTTGGGGGGTGAGCCCCG
GTTGCATCCAAGCTTCACAGCTTGGTTACGTTGCAGG	CCCGAGGAGGCCCTGCACGACCTCATGGTCTGGGCC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGCCCCAGTATGGCGATGGTCATGGCCCGGTCCGCCCA
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CAGGTCATGGGAATGTCGTAGTGGACCAGCCACTC
GTTGCATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CCCACGGCGGCTAGGGCCTCCCTAGCCCGCCCCAGTT
GTTACATCCAAGCTTCACAGCTTGGCTACGTTGCAGG

>NC_017273|1|1|102883-103876|PILER-CR
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGGCCCGGGAGCAACGTGGACCTCATCCGGGAGAAGTAGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CTCACCAACGGGGACGTACAGGAGGGGGACCTCCTCGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AGCGCCTTCGGCGGCGAGGAAATGTGCCCGGCGTGCAAGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CGCTCTCGACTTCGACCGCCTCACCGGCATCGGGGGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AAGGTTCTGGAGGCCCACAGCCTGGAGTGCATTCCCTAGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGGCCGATGCGGTGAACGTTTACAGGGGCGCGCAGGCCGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	GTCTTCCTCGACCCCCCGTACCGGGGCTACGAGGACGGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	AGGTTCGGGCAAGAGGTGGCCGACTACGTGGAGGCCGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	GTTTGCGGGGGGGTATGGGGTTTGGGGGGTGAGCCCCGGTTG
CATCCAAGCTTCACAGCTTGGTTACGTTGCAGG	CCCGAGGAGGCCCTGCACGACCTCATGGTCTGGGCCGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	TGCCCCAGTATGGCGATGGTCATGGCCCGGTCCGCCCAGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CAGGTCATGGGAATGTCGTAGTGGACCAGCCACTCGTTG
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG	CCCACGGCGGCTAGGGCCTCCCTAGCCCGCCCCAGTTGTTA
CATCCAAGCTTCACAGCTTGGCTACGTTGCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017273.1|WP_014511092.1|110776_111001_-|addiction-module-toxin,-HicA-family	unknown	unknown	gnl|CDD|377942
NC_017273.1|WP_014511084.1|92846_96101_+|ATP-binding-protein	unknown	unknown	gnl|CDD|224400
NC_017273.1|WP_014511085.1|96535_97618_+|CRISPR-associated-protein	cas7	cd09738_cas7_CAS-I-U	gnl|CDD|378223
NC_017273.1|WP_014511087.1|98977_101743_+|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl|CDD|187827
NC_017273.1|WP_014511086.1|97617_98991_+|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl|CDD|274005
NC_017273.1|WP_124105779.1|114652_115132_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511088.1|101739_102750_+|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	unknown
NC_017273.1|WP_008633013.1|115570_115759_-|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511081.1|91438_91798_+|hypothetical-protein	unknown	unknown	gnl|CDD|377579
NC_017273.1|WP_014511090.1|106483_109528_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|224000
NC_017273.1|WP_014511079.1|89404_89557_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|224514
NC_017273.1|WP_014511093.1|111135_111687_+|transposase	unknown	unknown	gnl|CDD|315923
NC_017273.1|WP_014511082.1|91810_92233_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NC_017273.1|WP_014511089.1|103912_106480_+|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl|CDD|378929
NC_017273.1|WP_014511091.1|110221_110692_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|197775
NC_017273.1|WP_029766039.1|109711_110065_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511083.1|92236_92794_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379154
NC_017273.1|WP_014511096.1|113211_114177_-|recombinase-XerD	unknown	unknown	gnl|CDD|274042
NC_017273.1|WP_014511080.1|89674_91261_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	unknown	unknown	gnl|CDD|273793
NC_017273.1|WP_081466172.1|115345_115525_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017273.1|WP_014511088.1|101739_102750_+|hypothetical-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	3.2e-17	57.6	0.2
NC_017273.1|WP_014511085.1|96535_97618_+|CRISPR-associated-protein	cas7	cd09738_cas7_CAS-I-U	5.6e-17	57.0	0.0
NC_017273.1|WP_014511087.1|98977_101743_+|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09696_cas3_CAS-I-U	2.6e-105	347.7	0.0
NC_017273.1|WP_014511086.1|97617_98991_+|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	2.9e-56	186.1	20.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017273.1|WP_014511092.1|110776_111001_-|addiction-module-toxin,-HicA-family	gnl|CDD|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	2.12117e-12
NC_017273.1|WP_014511084.1|92846_96101_+|ATP-binding-protein	gnl|CDD|224400	COG1483, COG1483, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.10727e-64
NC_017273.1|WP_014511085.1|96535_97618_+|CRISPR-associated-protein	gnl|CDD|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	6.39388e-18
NC_017273.1|WP_014511087.1|98977_101743_+|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|187827	cd09696, Cas3_I, CRISPR/Cas system-associated protein Cas3; Distinct Cas3 family with HD domain fused to C-termus of Helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DNA helicase Cas3; This protein includes both DEAH and HD motifs; signature gene for Type I.	8.67255e-100
NC_017273.1|WP_014511086.1|97617_98991_+|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl|CDD|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	2.14706e-49
NC_017273.1|WP_014511093.1|111135_111687_+|transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.03622e-17
NC_017273.1|WP_014511081.1|91438_91798_+|hypothetical-protein	gnl|CDD|377579	pfam05973, Gp49, Phage derived protein Gp49-like (DUF891). This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.	0.000249751
NC_017273.1|WP_014511090.1|106483_109528_+|AAA-family-ATPase	gnl|CDD|224000	COG1074, RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair].	4.57292e-84
NC_017273.1|WP_014511079.1|89404_89557_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	2.83054e-06
NC_017273.1|WP_014511082.1|91810_92233_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.64369e-09
NC_017273.1|WP_014511089.1|103912_106480_+|PD-(D/E)XK-nuclease-family-protein	gnl|CDD|378929	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	7.66056e-26
NC_017273.1|WP_014511091.1|110221_110692_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.02014e-06
NC_017273.1|WP_014511083.1|92236_92794_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379154	pfam13384, HTH_23, Homeodomain-like domain.	0.000212146
NC_017273.1|WP_014511096.1|113211_114177_-|recombinase-XerD	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	7.78944e-07
NC_017273.1|WP_014511080.1|89674_91261_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	1.13948e-11

Protein sequences

>NC_017273.1|WP_014511088.1|101739_102750_+|hypothetical-protein
MSAVWLEGLSLEGFPVAALAAYGALRLLVEEEGMEGVRLVFRDPQSRPVPGLLGVGEGELLCRLARRLRRVPPLPPELLEREKLEGLSPEEMRRLASADPRARRFLPALLLPLPGGGAFPSPLDTSKGQQRLTKTLRENWEAARRTHLLKGLRRVLFSGVLLGPGEVLWTWARVRGRASRRRSPLEFGLVGWHPSQYRQWAEGAREPSGLPFHEKVRIHPVATLLAWEAVPLFLLYPAPDGVRAAGVHDPEGRPSLLLPTPGHPVSLEALRALLLQAPLALQDPRAWPPEVALWRSPRLGHPKRQKDPYPVYVEARPVLRGPQAGAQTPGGSRRGR
>NC_017273.1|WP_014511087.1|98977_101743_+|type-I-U-CRISPR-associated-helicase/endonuclease-Cas3
MEALERAFAENPLTLEDFPGFFLEATGHEPYPWQEALLRRVVREGWPEAVAVPTGAGKTMVLAVALFLMALDPKAHRRVVYVVNRRLVVDQAHEVALGLKERLEEALARPSGEATPLVRAARRLAALGGGKPLEVVRLRGGVPRPRPTLQDPARPAVVLATVDMAGSRLLFRGYGVPRGLLPVEGALFGTDALYLLDEAHLEAPFLATLEAVAGLPGPWGRPGVRAVALTATPEGLGRGGIFRLGEADARHPRLGRILTASRRVWLRESPSRRRGKDLVAHALRLGEELGGPVAVVANRVGRALEVYRELGRAFPGRALLLTGRMRPRERDLNFARTRALQERLNRGEVAFVVATQALEVGADLDFAGMVTELADLSALKQRLGRVNRRGQRERAEVVVLGERETEAKEARPYLPEALQATWAWLAGLGAEGGVDLSPEALAQRMEAQPPPSEAFGRPRPPMPFLEAFLPLLAHTDPLVPLDPGPFLHGLERAAPEVEVVWRADLPETAEEVEAYLEAAPPGPKEGVRLPLYAVRAWLQGGAADLADLEGQEEEALRPGPPREGKAFRFDGEGVEEVSLRDPRLRPGDLLLVPAGFGGLSEGHWDPEAREPVPDVAEWGEERPRFLRLHPKVLAQALEDPEGAEGFGQELKERLLGAEGRREAREEVRRFLEERLSDFRAEWRPLVQAFLEGPFEVWPWGEGWGYGGYVLRLRQENPLYGSGRPEALEAHSRKVAEAVEDFARRLGLDPGVRAPFRRSALWHDLGKQDPRMQFWFLLSAGEAVDPSSRPLAKSGTRLTRKELERLRKEAGYPLGQRHEHVAARPLLGSHPLEAHLVATHHGRGRPLPAPSPDAPGFSVPLWAPWASWPGPPYGESAHGLERLESGYLENFLGLLKGMGPWGLAYGEALLRLADYLASGGEA
>NC_017273.1|WP_014511086.1|97617_98991_+|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MYLAFFVRYAVDAHRGKGPRGREFPPHEVRLRGGLVRSWALEGKPEEATKALEWLETLPPPGVLAPRVLEGNWRTRVAYVPPHDLPQPPGHREKVPLLHHVLPLSGRLLAYAYPLEGREEEAEAQLPTLGRLAGRISYLGTSRNLVWVEARLVEDPLGAYREEAGQEPWLLVPAEAGDLWMRVAPPGFLRLAEERFQARVRELPHRWVPYREPEALRSSQSLSPWGAWRVLALDPPLPLEWAPLFAHAARRALLSLLPPGAPPELTGHGAGGGPLRAPHLALVPLPNVGHRYGDGRVLGLAFLLPREAGGAVELALLEALLRLEEVRLDGLAVRLLPPDGRWALREGRWRRPARRFASVTPVVFDRYPKRGDVLAALRFSARAAGFPEPEEAWVLPYPRPQGVPLSRDFRLPPGVEGYVAHAEVLFPEPVSGPVLLGRGRYLGLGLFVPLEVEDGGA
>NC_017273.1|WP_014511085.1|96535_97618_+|CRISPR-associated-protein
MRPLLSQMALEVQVPLRVANPSGLVRSPAFSVDGGPFAPLRQTRYIRGEPVETVLLDSVESQANRQEALLYRHLPLPDVQVELFDGRRVSQYEAPGRILDAIFREATLGGQPSHQTPLFQAIARGGEEAERALFRHSPLTLVYGGWLSYGDISPEVAPKWPRLVALEILGLEPREAHRTSSRLDPLGVPGELPLPEAMSQALKEQGKKGRLSEAGLGRIPPTASPMDVAVRGAVLVGAVSLVGLRNLRLPQEAKEVLLALALLGLALQHKEGYRLRSGADLVPEEGGCLRVRALPSGEEVCLEVEPLREELDRLLGELPEELRWPGEPVVLQANETLNQLYRNALLGKAERAKAKREKEG
>NC_017273.1|WP_014511084.1|92846_96101_+|ATP-binding-protein
MALSNREIVGKGLDLLRSGLRPFVEREYRRVYGEEWVREAGEVLKGDRASLQDPDAQALLKLMDYRWNEVFDEKLGRWGRTLVKELLEFRNRWAHQGAFSFEDAHRALDSMTRLLEMIAAEEAQETVRMARELLRRRFEEEAKREAERAVKQSLAVVPQGLKPWREVVTPHPDVASGRYSEAEFAADLAQVHRGEAGEEYGNPLEFYRRTHLTSGLKRLLLNALKRLAGEGGDPVVELQTAFGGGKTHSMLALYHLFGGAVDPGEVPGLEDLLAQAGVARVPLARRAVFVGTAFSPARPHPKPEGVVVRTLWGEIAYQLGGVEGYRMLEEEDRTGVAPGSDVLKELFDRFSPALVLIDEWVAFLRNLYGEEGLPAGTFDQNLTFAQALTEAAKRSPRALVVASLPASDAEVGGGGGREALLRLQNVFGRLESVWQPATQDETYEIVRRRLFQPLSAEGYRVRDAVVREYVRYYREHRGEFPSEVLEPRYEERMRLAYPIHPELFDRLYEDWATLEGFQRTRGVLRLLASVVYTLWVRGDTSPLILPGGLPLDADGPRYELVRHLSRHQEGFDQVIDSDIDGPNAKAFALEKERPSLGRHQAARRAARAVFLATAPAGAAPTGKPRGVEGVRVKLGVAHPGESPALFTEALKALSERLVYFHAEGDRYWFETRPSLNRMAQDRAAAVSREEALMELEERLRAWAKGRPALFQGVHAAPAGSGEVADEPSLRLVVLSPRTPYAKGGSEAERWAREVLEGRGRAPRRYRNTLLFLAPEAVLVPDLEEAARQYLAWRSIWEDRESLNLGAADVRQVESRLRQAEDTLRLRLEEAYRHLLVFHQPDPKAPDLEVDALRLLGSGNPLERAASKAQNEGLVLVRWHPEFLGETLARYGFWEVAEPEGVLPLRRLWEDLASYLYLPRLKDEGVLLATVAQGVKEGRFGYAERLEGGVPKGVVLGEEVAPSLGGYLLKPEVAARFLKEKTGEDVPPPPDGEGDDEKVPVPPPPRPSRPRRFYLKKTLRMESLLPEVRALAEEVLLHLYKEGGVRLEVVLEAHAEAPEGFPEDLERVLRENSRVLGAEAFFEED
>NC_017273.1|WP_014511083.1|92236_92794_+|helix-turn-helix-domain-containing-protein
MESKSETIRRLYREGKSVSEIAKSLGLSYQRVYNTLKRSGFLKPKGRGPSPSGEPDPEAYARFLQGLEIRSMELMEVHAKLERSPKGKLSFRMGLEAFGPEPREGGFSAGLALSLDFQDEEGPFGFLRLRVRAGYATPLFPDEPLFRTFRERNLIVHLWPYLRLYVDFLTAQMGLPRLVLPAWKV
>NC_017273.1|WP_014511082.1|91810_92233_+|helix-turn-helix-domain-containing-protein
MGNNINFSDYFRESMKDPEARRLYREVLDEELSWLLSYLREERRLSQKEVAERLGVSRGRVSQLETSAGLSMSLESLARYAQALGLSLRLEFADERGEVLARFSLAADEPVAETTNPAWENAGAGWEPASGKASWASWAA
>NC_017273.1|WP_014511081.1|91438_91798_+|hypothetical-protein
MAQYRVELYRDARGYSQVLEFFNTLKRSNPKLLAFAQRLLKNLEEHGPDLRPPLAKPLKGLQAPIWELRHPSGLRLYYWRQGATLFVVAAGEVKKRDEADPDLLEFAVKAYRESQRNVN
>NC_017273.1|WP_014511080.1|89674_91261_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKAKPKAARKRTSQKRAKAFTGVHALLLFPSGEDHKATLDLMRRFSAGVRYAYNRLLEGQTREALKRENGPLRTFFRLNTRYADDAVMKAQAVLDSARERGEDPRKVVFGGRKLFETLRRRHLSGKPLKEVKREWKEKRQGLLYSRGDRTKGGNLNLRLEAEDGALWLRVNLGNGRYAWALVKTSHPNLSALVERVHASLPYNVELSLKDGKVHATFTWEEEPTPLAATKENGVLGIDVNSDPYHLALAVVGPDGNLKRHLTLSLEEVDRAPNRGTKELLLWKIAHQVVSLAEEHGVAVATERLKHLPKGRRGDGSGRAFRRKQHRFAYASLLRKVHSLARKKGVQVVEVNPQDTSAIGMLKYAPQLSLSKDVAAAYVIGRRALGFKEKLPKGYGKLLRDERFRDHAQGFYASRVRELQAKKAQEQNPYLRRRLSREIGKAKRHLSLLSSLQGSPGSQEGSTEGRNLLGGNPWRVLRVGLFLPLLGREVPRDLSPLKVILHRGAWEGWKGGLGPPPGGGPKCANVHFG
>NC_017273.1|WP_014511079.1|89404_89557_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MRKPLDYYLSLKYPVLLVAEPEGGYTALHPDLEGCVSVGETPEEVQTVGK
>NC_017273.1|WP_014511089.1|103912_106480_+|PD-(D/E)XK-nuclease-family-protein
MRAEDPGLIHVTPNRAVARRLGVPYRTLAGLARELLRDGGLLVASPYRARRLLVQAVREALAPKDPQGLAAALEGPVRTLLLLAQASGQGEEALARLAEEASPRLARVARAARRYGELLRGRRLLDPVEVLPKAAALGKRLPLRLWRYPYLGTGELAFLKGVAAPGSEVELLLPEGAWGEANRRAKEALEEVGLKVRPLELAGLGRAFLQGGGVGRVQALRFPDMEAEVRHVLASLKGLLRGGLPPGEVALVARDDRRYGPLVAAVGFDQGLPVRLLYRVPVGESRVGSLAALLAQALQDFPYEATLRLLFHPLFPWERKVDLDQARLRRPSGEAWKGLGLPGELLELAQGKTGGELVQGLRRALSPLRKRLEGWPRERAALEALLEGLGELEEEDREGFFQGISELLYHLTVPAQPGYGGVELHTPLARYGGAFRHLFVLGMAEGLTPVPVAEDPFLGLSEVEELERFGLFPEKPWEAAAREALVFAALLGSLKEDGEAVLTYPEVVEGRPVPMSPFLERLGLEPRSPGRTLVGSLVEARRLGLWEGDPLQEAMERALEAERARLEGEASSPHHGATGRPFLPASLSVSQLEDLATCPFRFYAKHLLRPRGDREAGDGDREDLGTFVHQVLARVFRAALEKDARRGEEVRALAAGGLLGEAFSRVEEEWKGRPNSPFFLRRPDWPHRRRWVLGLLARAFEDDKQFLRGDVKIVGVEVEAKLGRGFRGMVPGYEGLEVRGIIDRVEERSGSRFYLDYKLGSTSPRVKDPRTGKLSADLQLSLYILLHGEGRGAGVYYLLASREAKTVNLDRGALWAIFKEIRRTLKSGAFEPRPDAKAEACRSCPVELLCRYEGR
>NC_017273.1|WP_014511090.1|106483_109528_+|AAA-family-ATPase
MEANLYVAGAGTGKTYTLAERYLGFLEEGLSPLQVVAVTFTERAALELRHRVRQMVGERSLGHKERVLAELEAAPIGTLHALAARVCREFPEEAGVPADFQVMEDLEAALLLEAWLEEALLEALQDPRYAPLVEAVGYEGLLDTLREVAKDPLAARELLEKGLGEVAKALRLEAWRALRRRMEELFHGERPEERYPGFPKGWRTEEPEVVPDLLAWAGEVKFNKKPWLEYKGDPALERLLKLLGGVKEGFSPGPADERLEEVWPLLRELAEGVLARLEERRFRARRLGYADLEVHALRALEREEVRAYYRGRFRRLLVDEFQDTNPVQVRLLQALFPDLRAWTVVGDPNQSIYSFRRADPKVMERFQAEAAKEGLRVRRLEKSHRYHQGLADFHNRFFPPLLPGYGAVSAERKPEGEGPWVFHFQGDLEAQARFIAQEVGRLLSEGFQVYDLGEKAYRPMSLRDVAVLGRTWRDLARVAEALRRLEVPAVEAGGGNLLETRAFKDAYLALRFLGDPKDEEALVGLLRSPFFALTDGEVRRLAEARGEGETLWEVLEREGDLSAEAERARETLRGLLRRKALEAPSRLLQRLDGATGYTGVAARLPQGRRRVKDWEGTLDLVRKLEVGSEDPFLVARHLRLLLRSGLSVERPPLEAGEAVTLLTVHGAKGLEWPVVFVLNVGGWNRLGSWKNNKTKPLFRPGLALVPPVLDEEGNPSALFHLAKRRVEEEEKQEENRLLYVAATRASERLYLLLSPDLSPDKGDLDPQTLIGAGSLEKGLEATEPERPWSGEEGEVEVLEERIQGLPLEALPVSLLPLAARDPEAARRRLLGEPEPEGGEAWEPDGPQETEEEVPGGAGVGRMTHALLERFEAPEDLEREGRAFLEESFPGAEGEEVEEALRLARTFLTAEVFAPYRGNAVAKEVPVALELLGVRLEGRADRVGEDWVLDYKTDRGVDAKAYLLQVGVYALALGKPRALVADLREGKLYEGASQQVEEKAEEVLRRLMGGDRPEA
>NC_017273.1|WP_029766039.1|109711_110065_+|hypothetical-protein
MTERFLEVAKVSEAPLRARQAFPFPVRALHADATSFHVHGRYEGGEEEVGVLRIVHGDSRDHRPDLKPWGMGLVCADTEGHPPPLRSPGREGQRRQDPGGPVVPLPGGPGPLGGGLS
>NC_017273.1|WP_014511091.1|110221_110692_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MVRSWDVTYPCYIEHDPESGTYGGFCVDLPVFVAGKASVEEARKALEEGVAYYLAHLEVEERPFPRPGATPPPDLEEERDRLIPVEIRPSPVNPVSLAIEKALRRKGLKRKDLAERMGVPPSVVTRILDPLYFGHTLSTLRRVAEALEKDLVVAFR
>NC_017273.1|WP_014511092.1|110776_111001_-|addiction-module-toxin,-HicA-family
MGRLKRLSGRELRRLLRRHGFAPIKGRGKGSHEVWRNPQGMEVVIAVHDKDIVPIGTLKGILRQAGIPEEEVRQ
>NC_017273.1|WP_014511093.1|111135_111687_+|transposase
MRLTKHQRRPRLELKLRPHPDNLGHRLGLKPVYRRVWAPRGKTPLAWVRPRYRWLYVYGFARPSTGESEFWLLPPVNAAAFSEVLRQFARLRGSGERKLLLVILDRAGWHVSGRVEVPEGVGLVFLPPYSPELQPVERVWPLVNEAVAERCLVLAQDPETLRRRTLFHWWPRTKASAYTPSYS
>NC_017273.1|WP_014511096.1|113211_114177_-|recombinase-XerD
MREGLGLEVWDHPEERRRVVGEALERWDEGVLKEALWAYLVRHRKKPDRAAPHYVGYFVRWLALKGRRWPHLEPEDPKAFLLEAKERGFPGGERGPLSWGTVERARASLRHLFPFLDWAGHPMPSHVRLPSRQELPVVAPSRAMPEEAYQDLLEKAGAYPLAYWRPLLRVLLVLLGEVGLTVKEVADLWKEDVREKSLLVRGTKLREVPLSPLAREVLADWLPQRAFLASHQPLPYPHLLLKPAPGKNRGKPLGLGEAKWILTEFADFAGVKAEGKRRADLALPLRWRAIRRFLKEGHPREKVAYWTGMKSLVVPGWGEEG
>NC_017273.1|WP_124105779.1|114652_115132_+|hypothetical-protein
MQQDREHPLYYLDAETLLVATYIWVDDELKALQAQDFKLPPKQKHQKATLAELLTLAIFLLLQGQDLAKGYLAAKTTLKAYFPSLPHLSRFYRVLQKAQGLLAHLAMRLSGGQGLLQVVDLKPIPLAHGHRIHGLSLPEAAMGVGPLGAFAGYVHKLFP
>NC_017273.1|WP_081466172.1|115345_115525_+|hypothetical-protein
MGRVRNWIETSFSVMVRSSGLHRIEARSYWGLVARVNLILLVHNLIRSRVLLRMAGVEL
>NC_017273.1|WP_008633013.1|115570_115759_-|hypothetical-protein
MRLEGGGAWATAEVQVEALPARVVLSACSEGGACRSLALPREGGPFRLEGLSLAAKLLRYFC

Crispr_ID: NC_017273_2

• CRISPR_ID: NC_017273_2
• CRISPR_location: 116844-117310
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: cas2,cas1,cas4,cas8b5,cas5,cas3,cas6

Consensus repeat of NC_017273_2

Consensus_repeat	Method
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	PILER-CR
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CRISPRCasFinder
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CRT

spacers of NC_017273_2

>2.1|116880|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CCTCTCTGCCGCGAGCATCCTTCACCTCCAAAGGAA
>2.2|116952|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
ACCTCCAAAAACCTGCAGAGGAAAGAGCCTCACCAG
>2.3|117024|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CTACACGAAGCTCTGGAACAGGGGGGGCGGTAAGCT
>2.4|117096|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT
GGGTCTCGTCCTTCCCGTCCTTCCTAGGCATACTC
>2.5|117167|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
GGACCTCGCCATTTCCACCAGGGAGGACGCGGACTA
>2.6|117239|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
TATCACCGACGCCGCCATCGTACAAACCGGGAGTAG

CRISPR arrays and Neighbor proteins around NC_017273_2

CRISPR arrays

The CRISPR arrays of NC_017273_2

>merge|NC_017273|2|116844-117310|PILER-CR,CRISPRCasFinder,CRT
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCTCTCTGCCGCGAGCATCCTTCACCTCCAAAGGAAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACACCTCCAAAAACCTGCAGAGGAAAGAGCCTCACCAGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCTACACGAAGCTCTGGAACAGGGGGGGCGGTAAGCTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGGGTCTCGTCCTTCCCGTCCTTCCTAGGCATACTCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGGACCTCGCCATTTCCACCAGGGAGGACGCGGACTAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTATCACCGACGCCGCCATCGTACAAACCGGGAGTAGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

>NC_017273|2|2|116844-117310|PILER-CR
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCTCTCTGCCGCGAGCATCCTTCACCTCCAAAGGAA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ACCTCCAAAAACCTGCAGAGGAAAGAGCCTCACCAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTACACGAAGCTCTGGAACAGGGGGGGCGGTAAGCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGGTCTCGTCCTTCCCGTCCTTCCTAGGCATACTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGACCTCGCCATTTCCACCAGGGAGGACGCGGACTA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TATCACCGACGCCGCCATCGTACAAACCGGGAGTAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

>NC_017273|2|2|116844-117310|CRISPRCasFinder
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCTCTCTGCCGCGAGCATCCTTCACCTCCAAAGGAA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ACCTCCAAAAACCTGCAGAGGAAAGAGCCTCACCAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTACACGAAGCTCTGGAACAGGGGGGGCGGTAAGCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGGTCTCGTCCTTCCCGTCCTTCCTAGGCATACTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGACCTCGCCATTTCCACCAGGGAGGACGCGGACTA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TATCACCGACGCCGCCATCGTACAAACCGGGAGTAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

>NC_017273|2|2|116844-117310|CRT
GTATCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CCTCTCTGCCGCGAGCATCCTTCACCTCCAAAGGAA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	ACCTCCAAAAACCTGCAGAGGAAAGAGCCTCACCAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	CTACACGAAGCTCTGGAACAGGGGGGGCGGTAAGCT
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGGTCTCGTCCTTCCCGTCCTTCCTAGGCATACTC
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	GGACCTCGCCATTTCCACCAGGGAGGACGCGGACTA
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	TATCACCGACGCCGCCATCGTACAAACCGGGAGTAG
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017273.1|WP_124105779.1|114652_115132_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl|CDD|224124
NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_017273.1|WP_014511093.1|111135_111687_+|transposase	unknown	unknown	gnl|CDD|315923
NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187766
NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|273625
NC_017273.1|WP_014511096.1|113211_114177_-|recombinase-XerD	unknown	unknown	gnl|CDD|274042
NC_017273.1|WP_011229075.1|115834_116065_+|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	unknown
NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|379205
NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	gnl|CDD|235175
NC_017273.1|WP_029766039.1|109711_110065_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511097.1|116061_116475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|224761
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NC_017273.1|WP_008633013.1|115570_115759_-|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	unknown
NC_017273.1|WP_081466172.1|115345_115525_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NC_017273.1|WP_014511092.1|110776_111001_-|addiction-module-toxin,-HicA-family	unknown	unknown	gnl|CDD|377942
NC_017273.1|WP_014511091.1|110221_110692_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|197775

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	1.4e-47	157.2	0.0
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	4.3e-34	113.3	0.0
NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	3.1e-286	946.3	0.0
NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	1.7e-141	464.9	0.0
NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	3.6e-24	79.5	0.0
NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.2e-100	331.3	0.0
NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	2.8e-35	116.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.70281e-44
NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	2.50216e-16
NC_017273.1|WP_014511093.1|111135_111687_+|transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.03622e-17
NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.78454e-25
NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	8.15991e-114
NC_017273.1|WP_014511097.1|116061_116475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|224761	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.62294e-07
NC_017273.1|WP_014511096.1|113211_114177_-|recombinase-XerD	gnl|CDD|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	7.78944e-07
NC_017273.1|WP_014511092.1|110776_111001_-|addiction-module-toxin,-HicA-family	gnl|CDD|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	2.12117e-12
NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein	gnl|CDD|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	6.81597e-08
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.85041e-32
NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein	gnl|CDD|235175	PRK03918, PRK03918, DNA double-strand break repair ATPase Rad50.	1.30374e-06
NC_017273.1|WP_014511091.1|110221_110692_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.02014e-06
NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.21535e-34
NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|273625	TIGR01439, Uncharacterized_protein_Mb2626, looped-hinge helix DNA binding domain, AbrB family. This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609. [Regulatory functions, DNA interactions].	0.000568486

Protein sequences

>NC_017273.1|WP_014511097.1|116061_116475_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MIPERLVLDAGPLIALLHRSDPDHEEAVRGFRRLAEGGARLFLPMPVLFEVFKWLLFQAGPKAAREGLAKVEEGVVVVPFTLEDLEEVRLLLARLPGWGGTLEDAGVALLALRLGAPVWTLNYRDLGAFPALRFWTP
>NC_017273.1|WP_011229075.1|115834_116065_+|ribbon-helix-helix-protein,-CopG-family
MMMCDMRVTIYLPDHLAQEVEAYRKARPGLSLSALVRELLERELVKRPEALLEVAGLVERAELSAREHDALIREER
>NC_017273.1|WP_008633013.1|115570_115759_-|hypothetical-protein
MRLEGGGAWATAEVQVEALPARVVLSACSEGGACRSLALPREGGPFRLEGLSLAAKLLRYFC
>NC_017273.1|WP_081466172.1|115345_115525_+|hypothetical-protein
MGRVRNWIETSFSVMVRSSGLHRIEARSYWGLVARVNLILLVHNLIRSRVLLRMAGVEL
>NC_017273.1|WP_124105779.1|114652_115132_+|hypothetical-protein
MQQDREHPLYYLDAETLLVATYIWVDDELKALQAQDFKLPPKQKHQKATLAELLTLAIFLLLQGQDLAKGYLAAKTTLKAYFPSLPHLSRFYRVLQKAQGLLAHLAMRLSGGQGLLQVVDLKPIPLAHGHRIHGLSLPEAAMGVGPLGAFAGYVHKLFP
>NC_017273.1|WP_014511096.1|113211_114177_-|recombinase-XerD
MREGLGLEVWDHPEERRRVVGEALERWDEGVLKEALWAYLVRHRKKPDRAAPHYVGYFVRWLALKGRRWPHLEPEDPKAFLLEAKERGFPGGERGPLSWGTVERARASLRHLFPFLDWAGHPMPSHVRLPSRQELPVVAPSRAMPEEAYQDLLEKAGAYPLAYWRPLLRVLLVLLGEVGLTVKEVADLWKEDVREKSLLVRGTKLREVPLSPLAREVLADWLPQRAFLASHQPLPYPHLLLKPAPGKNRGKPLGLGEAKWILTEFADFAGVKAEGKRRADLALPLRWRAIRRFLKEGHPREKVAYWTGMKSLVVPGWGEEG
>NC_017273.1|WP_014511093.1|111135_111687_+|transposase
MRLTKHQRRPRLELKLRPHPDNLGHRLGLKPVYRRVWAPRGKTPLAWVRPRYRWLYVYGFARPSTGESEFWLLPPVNAAAFSEVLRQFARLRGSGERKLLLVILDRAGWHVSGRVEVPEGVGLVFLPPYSPELQPVERVWPLVNEAVAERCLVLAQDPETLRRRTLFHWWPRTKASAYTPSYS
>NC_017273.1|WP_014511092.1|110776_111001_-|addiction-module-toxin,-HicA-family
MGRLKRLSGRELRRLLRRHGFAPIKGRGKGSHEVWRNPQGMEVVIAVHDKDIVPIGTLKGILRQAGIPEEEVRQ
>NC_017273.1|WP_014511091.1|110221_110692_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MVRSWDVTYPCYIEHDPESGTYGGFCVDLPVFVAGKASVEEARKALEEGVAYYLAHLEVEERPFPRPGATPPPDLEEERDRLIPVEIRPSPVNPVSLAIEKALRRKGLKRKDLAERMGVPPSVVTRILDPLYFGHTLSTLRRVAEALEKDLVVAFR
>NC_017273.1|WP_029766039.1|109711_110065_+|hypothetical-protein
MTERFLEVAKVSEAPLRARQAFPFPVRALHADATSFHVHGRYEGGEEEVGVLRIVHGDSRDHRPDLKPWGMGLVCADTEGHPPPLRSPGREGQRRQDPGGPVVPLPGGPGPLGGGLS
>NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2
MRELYLVIAYDTPDDRRRARLAKLLKGFGERRQYSVFEARLTREQWAHLKGKLEALVNKEEDVLAVYFLPPEAVGRTWRIGHEGLKRLEDPDFV
>NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1
MAEGGGGVGVVYVLENEAYLSKEGGTLKVSRRAGREVLLQKPLIAVEEIVILGNAVVTPALLKHCAQEGVGIHYLSRTGTYYAGLTRTPSKNAPARVAQFKAHLEPTWKLALAQRFVLGKIRNGLVFLRRNGAEGWEGLKEALLEAERAQDEEALRGAEGRAADLYFRAFAELLPEEFAFGERSRRPPRDPANSLLSLAYTLLAKQCESALLVAGLDPYVGYLHEVRYGRPSLALDLMEEFRSVLADSVVLSLLNNRRVILEDFDDSEGFPRLRKEAWPKFLRAWEERLNERIQHPLLGKRLAYREILLAQARILVKHLLGELPRYEPFAVR
>NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4
MGHGGAVEYLPLSKVNTVVYCPRRFYLEYVLGEAHANHHLIEGHYLHERAYTEPGEESGLWVWSDRLGLLGVVDRLEWRRGEACPVEYKLGRAKEEAYLSDAVQLAAQALCLRESRGIEARRGFVYYHKSHTRREVVFTLELFRAVEAAVVRMRALLRSPRPPRVEVPPSKCEGCSVRGACQPELWRKGVAGWA
>NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein
MERVMVQASTVARAKRLVADVRFGEAPREALLAYKEALDEPEFGAFLERIDPRIVRYLRVAPGGSQALSDPKGKDLLLYLHPLPGERQMRAAYEVAIEGFLEHLETRGYPVVERGAGWVKVYVSPKAPSLDLEGAWKAYIEEAFSLEGLSARLLPLLNSVRLAGRGISAPKVPVPTLGARDFLAAWYLANLLSVKERLAWRDQEIRRLEEEVSRLPEGSERSRKLRELEKRRQDQEKELKKYGGELRKKWEEIVRKEAEKAEKRRRLEERLQRAKPKDKARIQDELRALESPLAEWALEGLGKAKDDPGRLWTWLDPESPEAPGAIQRLKPYLGRFGPLAKGQLNTAVGNKFTKILEELLRLLSLSSPEVEVPPLVSETPFTLDLRDPGDKADVCYGCGRPLGKDKLKASKLVFASPSQRLQSGNGQDEPWVCPSCAALALLSPIKPGEGSVLVRVGSYGAPEAAKHFARLLVTGTLHVAAGRYLLLNSPQVGGKPLTQALGRVVYALQALGQEVNPKVLERFPFYLVEGAQEIPLPPRALWLSHVLQRAFASRPDEGGEVNRPLGEALRYALGDLPWHALYTLARRYGRVADRFSLEDGLMRYASLLEKEVGMKENTDLSQRFRDVAGLTGLLSAWVGYVEGQVGRNSQEAKRAVVKLLDNLERPGDFLYVAAYHLDSTQARLYEAGGAFFYQEAKRLLQEAGARAQEAEEGSGRFLNVSQDDLHRVYAHLAARYPGKAWEGFIYEVRLSLASRFPQYIRMEKEG
>NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein
MPPKEERFSSATGGGRPWRRFGGWPRLLWRRTFRLWLPLPNMYAIALRIRPTSALTFRVLPGSILDIATYPFVPPTTLSGWLRRLFWAQEGLLPPDQREGNTPRFYVLPRRYLPLGAYPVGEWRVHRTHRHGPRAFTHSEFSRLRREGKPPKGGDLQLHTWEYLLAEEFLGAVLAEKEEDLRRLQGLVGYGAKLGKEGFAYLEAVGEPLEVRLEEGDAPFTPVRAEAWGGAIQGAYPLYRFRFGEAEDPDPASPDPSPVIGYEGAYFVLPRGRGLAKGFSLEGRFFAWDLVEFLWARASGGSSS
>NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'
MGEGIGRVFFLKDKVGFQPLSNHQGLVVKLLESWREGDEPLALSPKTKERLLLAARYHDDGKRFTFRIVPDGKGGLTYSFRGHRFRVAQAVQDPYAQALIRGHHDYSTREVVNLAADFLEEGLGHRFPEDLFLLMMADQLEAELAVRLWQGQAGEVRPFVEFDLLPDGEGGFLLDPWPFRVDEVALDFLVYFHPYRGEEAEVVEGWGRALVGALEEGKVPEAFQEETRRVRLRPWAAEARKADDPEAFYARFGLEPTPFQREVFKVAEGDPAHLLLAPTGTGKTEAAAFPALARGERLVFVLPTRSLVDDLEGRFRRYLKILAQEEGRPKALVVDTGHRQARFRFSPDGQEEATKERHLYHADVILTTLDKLLYRYFGYAEGVKSYTFPRRIHDRRTLFVFDEVHLYEATAWANFRHLIASLYKAGVRFLVMSATMPGTYREELLLEGTLEHPPAKRPSRVLRYMPQGNPMEIIQSHRGKRVLVVLEEVKEAAELYKRLKGEGVFLYHGRLAEGQRRRVFGEVKRRDEAQEPYLLITTPAIEVGVDLDAEVLVTTLCPPENLLQRLGRVNRRGRGQGEAYVVGETYPDYLGSLPEGYLELLKALDGQDLAQGGEERLRQAIRYPKYLDPRAETFFEALQEYVYGLDLTQEPLHRKGFVATRGWTPSVRLRQGEDEVEVPIDRLVGRKEELTPVRVVERLLTDGERGNRRWEEVPLRSGELYGRELVVDYPYPYDAELGFVELPKVFQRLRHPDPQRVQLLYAPEKDAGETPEGVMDTDQVTGGGRRVLWYLGESAWAESAKSGEVAEETEEEEEEGD
>NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6
MPQAVVLELVGEKPPLYPGRYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRVGPEGATLKGILRLRLTALDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL
>NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MELAKLSRKGQLSIPKRLLKALGVEGEAYFLVELAPEGGLLLRPAGVYPLEVYTEERLQELLAEDTLTEEERTRLAALAR
>NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein
MPPSPVRLHRLFLDANVLFAACWQEGRAQALLELAPRAKVLLLTSPHALEEARRNLEAKRPEALECLQRIRERVQTVPEAPMALVRKALAEGLPLKDAPILAAAWKAGAEALVTGDRRHFGHLMGRRVRGLWVVSLAEALAGVMGLLEDKG
>NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein
MKGYGVVVVVDTPPALRSEALEAVLRAADYAVLPTPPAPLDLEALVETVRRAVRPLGVAHRVLLTRVDPRSLGEALEAQTALMEAGVPAFHAFVRAYKAHERAALDGKPITRWRGPNAREAEADYRRVAEELLRELARTPERREA

Crispr_ID: NC_017273_3

• CRISPR_ID: NC_017273_3
• CRISPR_location: 128169-128930
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 10 spacers
• Cas_protein_info: cas6,cas3,cas5,cas8b5,cas4,cas1,cas2

Consensus repeat of NC_017273_3

Consensus_repeat	Method
GTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAAC	PILER-CR
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CRISPRCasFinder
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CRT

spacers of NC_017273_3

>3.1|128205|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
ATTAGTCACGGCCCAAATGGCCGACGGCGACTACGA
>3.2|128277|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CCGTTTAGAAAGCCAGCTTCTGAGCGCCCCTGAGGGAG
>3.3|128351|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT
TCCCGTGGCCTCCAGGGCCTCGGCTCCTCCCTCGGGG
>3.4|128424|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT
AACTCCCCGGCGAGATGGGCCACAGAGCGAACCCCTT
>3.5|128497|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CACTACCTAGTGCACCAGATGCACTAGTCTCGGGGCT
>3.6|128570|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
GCCGTGCGGCGTGCCGGGTGGTCTACGGCCCCCCGC
>3.7|128642|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
ACTACCAAGGGGCGAGAGGAGAGATTTGGTTCGGGA
>3.8|128714|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CCCGTAGCCGCCATTTGCTTTCCAAGCCACCACCT
>3.9|128785|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT
TTCTCGCACCCCTCCTCCTCGGCGCGTGGGTCCACCAC
>3.10|128859|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CAGATCTACCTCGGCCCGGGCGCCCTCGTGGACCCC

CRISPR arrays and Neighbor proteins around NC_017273_3

CRISPR arrays

The CRISPR arrays of NC_017273_3

>merge|NC_017273|3|128169-128930|PILER-CR,CRISPRCasFinder,CRT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACATTAGTCACGGCCCAAATGGCCGACGGCGACTACGAGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCCGTTTAGAAAGCCAGCTTCTGAGCGCCCCTGAGGGAGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACTCCCGTGGCCTCCAGGGCCTCGGCTCCTCCCTCGGGGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACAACTCCCCGGCGAGATGGGCCACAGAGCGAACCCCTTGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCACTACCTAGTGCACCAGATGCACTAGTCTCGGGGCTGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACGCCGTGCGGCGTGCCGGGTGGTCTACGGCCCCCCGCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACACTACCAAGGGGCGAGAGGAGAGATTTGGTTCGGGAGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCCCGTAGCCGCCATTTGCTTTCCAAGCCACCACCTGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACTTCTCGCACCCCTCCTCCTCGGCGCGTGGGTCCACCACGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCAGATCTACCTCGGCCCGGGCGCCCTCGTGGACCCCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC

>NC_017273|3|3|128169-128930|PILER-CR
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	ATTAGTCACGGCCCAAATGGCCGACGGCGACTACGA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CCGTTTAGAAAGCCAGCTTCTGAGCGCCCCTGAGGGAG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TCCCGTGGCCTCCAGGGCCTCGGCTCCTCCCTCGGGG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	AACTCCCCGGCGAGATGGGCCACAGAGCGAACCCCTT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CACTACCTAGTGCACCAGATGCACTAGTCTCGGGGCT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GCCGTGCGGCGTGCCGGGTGGTCTACGGCCCCCCGC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	ACTACCAAGGGGCGAGAGGAGAGATTTGGTTCGGGA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CCCGTAGCCGCCATTTGCTTTCCAAGCCACCACCT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTCTCGCACCCCTCCTCCTCGGCGCGTGGGTCCACCAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CAGATCTACCTCGGCCCGGGCGCCCTCGTGGACCCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC

>NC_017273|3|3|128169-128930|CRISPRCasFinder
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	ATTAGTCACGGCCCAAATGGCCGACGGCGACTACGA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CCGTTTAGAAAGCCAGCTTCTGAGCGCCCCTGAGGGAG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TCCCGTGGCCTCCAGGGCCTCGGCTCCTCCCTCGGGG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	AACTCCCCGGCGAGATGGGCCACAGAGCGAACCCCTT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CACTACCTAGTGCACCAGATGCACTAGTCTCGGGGCT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GCCGTGCGGCGTGCCGGGTGGTCTACGGCCCCCCGC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	ACTACCAAGGGGCGAGAGGAGAGATTTGGTTCGGGA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CCCGTAGCCGCCATTTGCTTTCCAAGCCACCACCT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTCTCGCACCCCTCCTCCTCGGCGCGTGGGTCCACCAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CAGATCTACCTCGGCCCGGGCGCCCTCGTGGACCCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC

>NC_017273|3|3|128169-128930|CRT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	ATTAGTCACGGCCCAAATGGCCGACGGCGACTACGA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CCGTTTAGAAAGCCAGCTTCTGAGCGCCCCTGAGGGAG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TCCCGTGGCCTCCAGGGCCTCGGCTCCTCCCTCGGGG
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	AACTCCCCGGCGAGATGGGCCACAGAGCGAACCCCTT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CACTACCTAGTGCACCAGATGCACTAGTCTCGGGGCT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	GCCGTGCGGCGTGCCGGGTGGTCTACGGCCCCCCGC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	ACTACCAAGGGGCGAGAGGAGAGATTTGGTTCGGGA
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CCCGTAGCCGCCATTTGCTTTCCAAGCCACCACCT
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	TTCTCGCACCCCTCCTCCTCGGCGCGTGGGTCCACCAC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC	CAGATCTACCTCGGCCCGGGCGCCCTCGTGGACCCC
GTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017273.1|WP_014511110.1|131908_132850_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|234698
NC_017273.1|WP_014511109.1|131499_131862_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl|CDD|224124
NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_017273.1|WP_008633599.1|137440_137683_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|273625
NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187766
NC_017273.1|WP_014511097.1|116061_116475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|224761
NC_017273.1|WP_014511111.1|132852_133329_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350222
NC_017273.1|WP_011229075.1|115834_116065_+|ribbon-helix-helix-protein,-CopG-family	unknown	unknown	unknown
NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|379205
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NC_017273.1|WP_008633013.1|115570_115759_-|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014630458.1|134817_135138_-|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|225209
NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	gnl|CDD|235175
NC_017273.1|WP_014511107.1|137004_137460_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|379205
NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	unknown
NC_017273.1|WP_014511116.1|138954_140715_-|GMC-family-oxidoreductase	unknown	unknown	gnl|CDD|225186
NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|273040
NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|273625

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	3.6e-24	79.5	0.0
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	1.4e-47	157.2	0.0
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	4.3e-34	113.3	0.0
NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein	cas8b5	mkCas0131_cas8b5_CAS-I-B	3.1e-286	946.3	0.0
NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	1.7e-141	464.9	0.0
NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	1.2e-100	331.3	0.0
NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	2.8e-35	116.8	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017273.1|WP_014511110.1|131908_132850_-|tyrosine-type-recombinase/integrase	gnl|CDD|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	5.99641e-78
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.70281e-44
NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	2.50216e-16
NC_017273.1|WP_008633599.1|137440_137683_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|273625	TIGR01439, Uncharacterized_protein_Mb2626, looped-hinge helix DNA binding domain, AbrB family. This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609. [Regulatory functions, DNA interactions].	0.000519482
NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.78454e-25
NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	8.15991e-114
NC_017273.1|WP_014511097.1|116061_116475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|224761	COG1848, COG1848, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	2.62294e-07
NC_017273.1|WP_014511111.1|132852_133329_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350222	cd09874, PIN_MT3492-like, VapC-like PIN domain of the hypothetical protein MT3492 of Mycobacterium tuberculosis CDC1551 and other uncharacterized, annotated PilT protein domain proteins. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis CDC1551, hypothetical protein MT3492, and similar bacterial and archaeal proteins are included in this subfamily. They are PIN domain homologs of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	3.21075e-26
NC_017273.1|WP_014511107.1|137004_137460_-|PIN-domain-containing-protein	gnl|CDD|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	6.81597e-08
NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein	gnl|CDD|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	6.81597e-08
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.85041e-32
NC_017273.1|WP_014511116.1|138954_140715_-|GMC-family-oxidoreductase	gnl|CDD|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	4.71102e-84
NC_017273.1|WP_014630458.1|134817_135138_-|antibiotic-biosynthesis-monooxygenase	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	7.87173e-31
NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein	gnl|CDD|235175	PRK03918, PRK03918, DNA double-strand break repair ATPase Rad50.	1.30374e-06
NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4	gnl|CDD|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.21535e-34
NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|273625	TIGR01439, Uncharacterized_protein_Mb2626, looped-hinge helix DNA binding domain, AbrB family. This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609. [Regulatory functions, DNA interactions].	0.000568486

Protein sequences

>NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6
MPQAVVLELVGEKPPLYPGRYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRVGPEGATLKGILRLRLTALDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL
>NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'
MGEGIGRVFFLKDKVGFQPLSNHQGLVVKLLESWREGDEPLALSPKTKERLLLAARYHDDGKRFTFRIVPDGKGGLTYSFRGHRFRVAQAVQDPYAQALIRGHHDYSTREVVNLAADFLEEGLGHRFPEDLFLLMMADQLEAELAVRLWQGQAGEVRPFVEFDLLPDGEGGFLLDPWPFRVDEVALDFLVYFHPYRGEEAEVVEGWGRALVGALEEGKVPEAFQEETRRVRLRPWAAEARKADDPEAFYARFGLEPTPFQREVFKVAEGDPAHLLLAPTGTGKTEAAAFPALARGERLVFVLPTRSLVDDLEGRFRRYLKILAQEEGRPKALVVDTGHRQARFRFSPDGQEEATKERHLYHADVILTTLDKLLYRYFGYAEGVKSYTFPRRIHDRRTLFVFDEVHLYEATAWANFRHLIASLYKAGVRFLVMSATMPGTYREELLLEGTLEHPPAKRPSRVLRYMPQGNPMEIIQSHRGKRVLVVLEEVKEAAELYKRLKGEGVFLYHGRLAEGQRRRVFGEVKRRDEAQEPYLLITTPAIEVGVDLDAEVLVTTLCPPENLLQRLGRVNRRGRGQGEAYVVGETYPDYLGSLPEGYLELLKALDGQDLAQGGEERLRQAIRYPKYLDPRAETFFEALQEYVYGLDLTQEPLHRKGFVATRGWTPSVRLRQGEDEVEVPIDRLVGRKEELTPVRVVERLLTDGERGNRRWEEVPLRSGELYGRELVVDYPYPYDAELGFVELPKVFQRLRHPDPQRVQLLYAPEKDAGETPEGVMDTDQVTGGGRRVLWYLGESAWAESAKSGEVAEETEEEEEEGD
>NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein
MPPKEERFSSATGGGRPWRRFGGWPRLLWRRTFRLWLPLPNMYAIALRIRPTSALTFRVLPGSILDIATYPFVPPTTLSGWLRRLFWAQEGLLPPDQREGNTPRFYVLPRRYLPLGAYPVGEWRVHRTHRHGPRAFTHSEFSRLRREGKPPKGGDLQLHTWEYLLAEEFLGAVLAEKEEDLRRLQGLVGYGAKLGKEGFAYLEAVGEPLEVRLEEGDAPFTPVRAEAWGGAIQGAYPLYRFRFGEAEDPDPASPDPSPVIGYEGAYFVLPRGRGLAKGFSLEGRFFAWDLVEFLWARASGGSSS
>NC_017273.1|WP_014511101.1|120738_123039_+|hypothetical-protein
MERVMVQASTVARAKRLVADVRFGEAPREALLAYKEALDEPEFGAFLERIDPRIVRYLRVAPGGSQALSDPKGKDLLLYLHPLPGERQMRAAYEVAIEGFLEHLETRGYPVVERGAGWVKVYVSPKAPSLDLEGAWKAYIEEAFSLEGLSARLLPLLNSVRLAGRGISAPKVPVPTLGARDFLAAWYLANLLSVKERLAWRDQEIRRLEEEVSRLPEGSERSRKLRELEKRRQDQEKELKKYGGELRKKWEEIVRKEAEKAEKRRRLEERLQRAKPKDKARIQDELRALESPLAEWALEGLGKAKDDPGRLWTWLDPESPEAPGAIQRLKPYLGRFGPLAKGQLNTAVGNKFTKILEELLRLLSLSSPEVEVPPLVSETPFTLDLRDPGDKADVCYGCGRPLGKDKLKASKLVFASPSQRLQSGNGQDEPWVCPSCAALALLSPIKPGEGSVLVRVGSYGAPEAAKHFARLLVTGTLHVAAGRYLLLNSPQVGGKPLTQALGRVVYALQALGQEVNPKVLERFPFYLVEGAQEIPLPPRALWLSHVLQRAFASRPDEGGEVNRPLGEALRYALGDLPWHALYTLARRYGRVADRFSLEDGLMRYASLLEKEVGMKENTDLSQRFRDVAGLTGLLSAWVGYVEGQVGRNSQEAKRAVVKLLDNLERPGDFLYVAAYHLDSTQARLYEAGGAFFYQEAKRLLQEAGARAQEAEEGSGRFLNVSQDDLHRVYAHLAARYPGKAWEGFIYEVRLSLASRFPQYIRMEKEG
>NC_017273.1|WP_041444555.1|118798_119383_-|CRISPR-associated-protein-Cas4
MGHGGAVEYLPLSKVNTVVYCPRRFYLEYVLGEAHANHHLIEGHYLHERAYTEPGEESGLWVWSDRLGLLGVVDRLEWRRGEACPVEYKLGRAKEEAYLSDAVQLAAQALCLRESRGIEARRGFVYYHKSHTRREVVFTLELFRAVEAAVVRMRALLRSPRPPRVEVPPSKCEGCSVRGACQPELWRKGVAGWA
>NC_017273.1|WP_081466159.1|117830_118829_-|CRISPR-associated-endonuclease-Cas1
MAEGGGGVGVVYVLENEAYLSKEGGTLKVSRRAGREVLLQKPLIAVEEIVILGNAVVTPALLKHCAQEGVGIHYLSRTGTYYAGLTRTPSKNAPARVAQFKAHLEPTWKLALAQRFVLGKIRNGLVFLRRNGAEGWEGLKEALLEAERAQDEEALRGAEGRAADLYFRAFAELLPEEFAFGERSRRPPRDPANSLLSLAYTLLAKQCESALLVAGLDPYVGYLHEVRYGRPSLALDLMEEFRSVLADSVVLSLLNNRRVILEDFDDSEGFPRLRKEAWPKFLRAWEERLNERIQHPLLGKRLAYREILLAQARILVKHLLGELPRYEPFAVR
>NC_017273.1|WP_011174371.1|117549_117834_-|CRISPR-associated-endonuclease-Cas2
MRELYLVIAYDTPDDRRRARLAKLLKGFGERRQYSVFEARLTREQWAHLKGKLEALVNKEEDVLAVYFLPPEAVGRTWRIGHEGLKRLEDPDFV
>NC_017273.1|WP_014511097.1|116061_116475_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MIPERLVLDAGPLIALLHRSDPDHEEAVRGFRRLAEGGARLFLPMPVLFEVFKWLLFQAGPKAAREGLAKVEEGVVVVPFTLEDLEEVRLLLARLPGWGGTLEDAGVALLALRLGAPVWTLNYRDLGAFPALRFWTP
>NC_017273.1|WP_011229075.1|115834_116065_+|ribbon-helix-helix-protein,-CopG-family
MMMCDMRVTIYLPDHLAQEVEAYRKARPGLSLSALVRELLERELVKRPEALLEVAGLVERAELSAREHDALIREER
>NC_017273.1|WP_008633013.1|115570_115759_-|hypothetical-protein
MRLEGGGAWATAEVQVEALPARVVLSACSEGGACRSLALPREGGPFRLEGLSLAAKLLRYFC
>NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MELAKLSRKGQLSIPKRLLKALGVEGEAYFLVELAPEGGLLLRPAGVYPLEVYTEERLQELLAEDTLTEEERTRLAALAR
>NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein
MPPSPVRLHRLFLDANVLFAACWQEGRAQALLELAPRAKVLLLTSPHALEEARRNLEAKRPEALECLQRIRERVQTVPEAPMALVRKALAEGLPLKDAPILAAAWKAGAEALVTGDRRHFGHLMGRRVRGLWVVSLAEALAGVMGLLEDKG
>NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein
MKGYGVVVVVDTPPALRSEALEAVLRAADYAVLPTPPAPLDLEALVETVRRAVRPLGVAHRVLLTRVDPRSLGEALEAQTALMEAGVPAFHAFVRAYKAHERAALDGKPITRWRGPNAREAEADYRRVAEELLRELARTPERREA
>NC_017273.1|WP_014511109.1|131499_131862_+|hypothetical-protein
MKRKRLAELVREEAGDLQEAPAPREERPGEAPHGGGLEGSPPGEGQGERPLPPYLTYVRKECRLRPDQLDALTALARRLNRERRGKGERITENTLIRWAVDMLLENYRNSDIFHSEDKGD
>NC_017273.1|WP_014511110.1|131908_132850_-|tyrosine-type-recombinase/integrase
MVAAQDPHAELLHRFRRYLEMEEGRSPRTAKEYLMDAGLFARWFRERHGRPPRFEEVGSQHIRAFLASREVSPHRAGRVLASLRKLFRYLAEVEGLPILKDPTEGVKRPKLPRRLPVYLTPPEVARLLQAAYQNRSPRVALRDWALLAFLYGTGLRLSEALALTYADITYQDGIPHAIRVQGKGGKERVVVLSPTAQRALHQWLKHRNLEGHPTSPYIWSHTTGPNRGKPFSARAVEAMVKRVARRAGLKDWRRITPHKLRHSYASALVEAGRGIDEVKELLGHSSISTTQVYVHVSRKRLEEAARALPDVVG
>NC_017273.1|WP_014511111.1|132852_133329_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MPSSRTSDAEPLFLDTSVLVRLYYLEPEDPFEWAVDLAQRPGTLLAASHLAYVETLATFHALRRGRAITSRRQASLSAAFRADWPAFLRVPLSPPVVQLAGALAEEHPLRGADALQLASFAWLWEKEGKGRFFTLDRRLYLVARDLVPTVPVPAFEEV
>NC_017273.1|WP_014630458.1|134817_135138_-|antibiotic-biosynthesis-monooxygenase
MFVTMNRIPVRPEYAEQFEEAFRQRARLVDRMPGFIRNLVLRPKDPGDPYVVMTLWESEEAFRAWTESPAFKEGHARSGTLPKEAFLGPSRLEAFEVVLDSEGQDA
>NC_017273.1|WP_014511107.1|137004_137460_-|PIN-domain-containing-protein
MPPSPVRLHRLFLDANVLFAACWQEGRAQALLELAPRAKVLLLTSPHALEEARRNLEAKRPEALECLQRIRERVQTVPEAPMALVRKALAEGLPLKDAPILAAAWKAGAEALVTGDRRHFGHLMGRRVRGLWVVSLAEALAGVMGLLEDKG
>NC_017273.1|WP_008633599.1|137440_137683_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MELAKLSRKGQLSIPKRLLKALGVEGEAYFLVELAPEGGLLLRPAGVYPLEVYTEERLQELLAEDTLTEEERARLAALAR
>NC_017273.1|WP_014511116.1|138954_140715_-|GMC-family-oxidoreductase
MAKRLKPVDVVLVGVGWTGGILAKELAQAGYRVVGLERGHYRDTIPDFQLPWIHDELRYAVRYELMQDLSRETITFRNNRNQTARPMRVLGSFLPGEGLGGAGVHWNGVTWRFLPYDFEMRTKTLERYGPSAIPEGSTIQDWGITYEELEPYYDKFEYTCGIAGKAGNLKGVIQPGGNPFEGPRNREYPNPPMKTSYAGHLFRQAAQELGYHPFPQPSANVTQPYTNPDGVQLGACVYCGYCERFGCEVNAKASPQTTVLPVAFRTGNFELRTEAYVTRINLSPDKRQAVSVSYVDLKTGEEYEQPAEVICLTSYVLNNVRLLLLSGIGKPYDPVTGQGVVGRNYAYQAFTSVVLFFEDKVFNPFMGAGALGVSIDDFNGDNFDHGGLGFIGGGNIACSTTGARPIQSLRVPPGTPRWGAEWKKAVARYYQRNFSISFQGGVLPYRTNYLDLDPTYKDAFGLPLLRMTFDWGPNEHRASQFAAQVLERIARAIGPKTYVINRLSEHYSIVPYQSTHNTGGAVMGSDPSTSVVNKYLQSWDVPNVFVVGASAFPQNAGYNPTGTVGALAFWAADAVKRYLQRPGPLV

Crispr_ID: NC_017273_4

• CRISPR_ID: NC_017273_4
• CRISPR_location: 136049-136163
• CRISPR_type: Unclear
• Repeat_type: III-A
• Spacer_info: 1 spacers
• Cas_protein_info: cas6,cas3,cas5

Consensus repeat of NC_017273_4

Consensus_repeat	Method
CAATCCCCTTACGGGGCTCAATCCCTTGCAAC	CRISPRCasFinder

spacers of NC_017273_4

>4.1|136081|51|NC_017273|CRISPRCasFinder
GATGACTCCAAGCCCATTGCTAAGGTTGGTTGACGACTATGAGTTCGGTCG

CRISPR arrays and Neighbor proteins around NC_017273_4

CRISPR arrays

The CRISPR arrays of NC_017273_4

>merge|NC_017273|4|136049-136163|CRISPRCasFinder
CAATCCCCTTACGGGGCTCAATCCCTTGCAACGATGACTCCAAGCCCATTGCTAAGGTTGGTTGACGACTATGAGTTCGGTCGCAATCCCCTTACGGGGCTCAATCCCTTGCAAC

>NC_017273|4|4|136049-136163|CRISPRCasFinder
CAATCCCCTTACGGGGCTCAATCCCTTGCAAC	GATGACTCCAAGCCCATTGCTAAGGTTGGTTGACGACTATGAGTTCGGTCG
CAATCCCCTTACGGGGCTCAATCCCTTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017273.1|WP_014511110.1|131908_132850_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|234698
NC_017273.1|WP_014511109.1|131499_131862_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl|CDD|224124
NC_017273.1|WP_014511122.1|147953_148760_-|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NC_017273.1|WP_014511118.1|142382_143474_-|IS4-family-transposase	unknown	unknown	gnl|CDD|376573
NC_017273.1|WP_008633599.1|137440_137683_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|273625
NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	unknown
NC_017273.1|WP_041445145.1|149059_150145_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|316042
NC_017273.1|WP_014511121.1|147346_147874_-|hypothetical-protein	unknown	unknown	gnl|CDD|260008
NC_017273.1|WP_014511117.1|140718_141519_-|gluconate-2-dehydrogenase-subunit-3-family-protein	unknown	unknown	gnl|CDD|379295
NC_017273.1|WP_014511107.1|137004_137460_-|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|379205
NC_017273.1|WP_014511111.1|132852_133329_-|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350222
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|273848
NC_017273.1|WP_014511116.1|138954_140715_-|GMC-family-oxidoreductase	unknown	unknown	gnl|CDD|225186
NC_017273.1|WP_014630458.1|134817_135138_-|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl|CDD|225209
NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein	unknown	unknown	gnl|CDD|379205
NC_017273.1|WP_014511120.1|144775_146944_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|334157
NC_017273.1|WP_041445142.1|143659_144760_+|transposase	unknown	unknown	gnl|CDD|379252
NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|273625

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein	cas5	cls000047_cas5_CAS-I-B	1.7e-141	464.9	0.0
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	1.4e-47	157.2	0.0
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	4.3e-34	113.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017273.1|WP_014511110.1|131908_132850_-|tyrosine-type-recombinase/integrase	gnl|CDD|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	5.99641e-78
NC_017273.1|WP_014511118.1|142382_143474_-|IS4-family-transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	2.43217e-09
NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.70281e-44
NC_017273.1|WP_041445145.1|149059_150145_-|AAA-family-ATPase	gnl|CDD|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	3.58574e-09
NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	2.50216e-16
NC_017273.1|WP_014511121.1|147346_147874_-|hypothetical-protein	gnl|CDD|260008	cd09276, Rnase_HI_RT_non_LTR, non-LTR RNase HI domain of reverse transcriptases. Ribonuclease H (RNase H) is classified into two families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). Ribonuclease HI (RNase HI) is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes. RNase HI has also been observed as an adjunct domain to the reverse transcriptase gene in retroviruses, long-term repeat (LTR)-bearing retrotransposons and non-LTR retrotransposons. RNase HI in LTR retrotransposons perform degradation of the original RNA template, generation of a polypurine tract (the primer for plus-strand DNA synthesis), and final removal of RNA primers from newly synthesized minus and plus strands. The catalytic residues for RNase H enzymatic activity, three aspartatic acids and one glutamic acid residue (DEDD), are unvaried across all RNase H domains. The position of the RNase domain of non-LTR and LTR transposons is at the carboxyl terminal of the reverse transcriptase (RT) domain and their RNase domains group together, indicating a common evolutionary origin. Many non-LTR transposons have lost the RNase domain because their activity is at the nucleus and cellular RNase may suffice; however LTR retrotransposons always encode their own RNase domain because it requires RNase activity in RNA-protein particles in the cytoplasm. RNase H inhibitors have been explored as an anti-HIV drug target because RNase H inactivation inhibits reverse transcription.	9.26304e-13
NC_017273.1|WP_008633599.1|137440_137683_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|273625	TIGR01439, Uncharacterized_protein_Mb2626, looped-hinge helix DNA binding domain, AbrB family. This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609. [Regulatory functions, DNA interactions].	0.000519482
NC_017273.1|WP_014511117.1|140718_141519_-|gluconate-2-dehydrogenase-subunit-3-family-protein	gnl|CDD|379295	pfam13618, Gluconate_2-dh3, Gluconate 2-dehydrogenase subunit 3. This family corresponds to subunit 3 of the Gluconate 2-dehydrogenase enzyme that catalyzes the conversion of gluconate to 2-dehydro-D-gluconate EC:1.1.99.3.	2.65863e-43
NC_017273.1|WP_014511107.1|137004_137460_-|PIN-domain-containing-protein	gnl|CDD|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	6.81597e-08
NC_017273.1|WP_014511111.1|132852_133329_-|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350222	cd09874, PIN_MT3492-like, VapC-like PIN domain of the hypothetical protein MT3492 of Mycobacterium tuberculosis CDC1551 and other uncharacterized, annotated PilT protein domain proteins. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis CDC1551, hypothetical protein MT3492, and similar bacterial and archaeal proteins are included in this subfamily. They are PIN domain homologs of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	3.21075e-26
NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6	gnl|CDD|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.85041e-32
NC_017273.1|WP_014511116.1|138954_140715_-|GMC-family-oxidoreductase	gnl|CDD|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	4.71102e-84
NC_017273.1|WP_014630458.1|134817_135138_-|antibiotic-biosynthesis-monooxygenase	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	7.87173e-31
NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein	gnl|CDD|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	6.81597e-08
NC_017273.1|WP_014511120.1|144775_146944_+|AAA-family-ATPase	gnl|CDD|334157	pfam00580, UvrD-helicase, UvrD/REP helicase N-terminal domain. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Some members have large insertions near to the carboxy-terminus relative to other members of the family.	6.40386e-15
NC_017273.1|WP_041445142.1|143659_144760_+|transposase	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	0.000467782
NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|273625	TIGR01439, Uncharacterized_protein_Mb2626, looped-hinge helix DNA binding domain, AbrB family. This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609. [Regulatory functions, DNA interactions].	0.000568486

Protein sequences

>NC_017273.1|WP_014630458.1|134817_135138_-|antibiotic-biosynthesis-monooxygenase
MFVTMNRIPVRPEYAEQFEEAFRQRARLVDRMPGFIRNLVLRPKDPGDPYVVMTLWESEEAFRAWTESPAFKEGHARSGTLPKEAFLGPSRLEAFEVVLDSEGQDA
>NC_017273.1|WP_014511111.1|132852_133329_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MPSSRTSDAEPLFLDTSVLVRLYYLEPEDPFEWAVDLAQRPGTLLAASHLAYVETLATFHALRRGRAITSRRQASLSAAFRADWPAFLRVPLSPPVVQLAGALAEEHPLRGADALQLASFAWLWEKEGKGRFFTLDRRLYLVARDLVPTVPVPAFEEV
>NC_017273.1|WP_014511110.1|131908_132850_-|tyrosine-type-recombinase/integrase
MVAAQDPHAELLHRFRRYLEMEEGRSPRTAKEYLMDAGLFARWFRERHGRPPRFEEVGSQHIRAFLASREVSPHRAGRVLASLRKLFRYLAEVEGLPILKDPTEGVKRPKLPRRLPVYLTPPEVARLLQAAYQNRSPRVALRDWALLAFLYGTGLRLSEALALTYADITYQDGIPHAIRVQGKGGKERVVVLSPTAQRALHQWLKHRNLEGHPTSPYIWSHTTGPNRGKPFSARAVEAMVKRVARRAGLKDWRRITPHKLRHSYASALVEAGRGIDEVKELLGHSSISTTQVYVHVSRKRLEEAARALPDVVG
>NC_017273.1|WP_014511109.1|131499_131862_+|hypothetical-protein
MKRKRLAELVREEAGDLQEAPAPREERPGEAPHGGGLEGSPPGEGQGERPLPPYLTYVRKECRLRPDQLDALTALARRLNRERRGKGERITENTLIRWAVDMLLENYRNSDIFHSEDKGD
>NC_017273.1|WP_014511108.1|131065_131503_+|ParA-family-protein
MKGYGVVVVVDTPPALRSEALEAVLRAADYAVLPTPPAPLDLEALVETVRRAVRPLGVAHRVLLTRVDPRSLGEALEAQTALMEAGVPAFHAFVRAYKAHERAALDGKPITRWRGPNAREAEADYRRVAEELLRELARTPERREA
>NC_017273.1|WP_014511107.1|130552_131008_+|PIN-domain-containing-protein
MPPSPVRLHRLFLDANVLFAACWQEGRAQALLELAPRAKVLLLTSPHALEEARRNLEAKRPEALECLQRIRERVQTVPEAPMALVRKALAEGLPLKDAPILAAAWKAGAEALVTGDRRHFGHLMGRRVRGLWVVSLAEALAGVMGLLEDKG
>NC_017273.1|WP_014511106.1|130329_130572_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MELAKLSRKGQLSIPKRLLKALGVEGEAYFLVELAPEGGLLLRPAGVYPLEVYTEERLQELLAEDTLTEEERTRLAALAR
>NC_017273.1|WP_014511105.1|127134_127929_+|CRISPR-associated-endoribonuclease-Cas6
MPQAVVLELVGEKPPLYPGRYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRVGPEGATLKGILRLRLTALDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL
>NC_017273.1|WP_014511104.1|124681_127135_+|CRISPR-associated-helicase-Cas3'
MGEGIGRVFFLKDKVGFQPLSNHQGLVVKLLESWREGDEPLALSPKTKERLLLAARYHDDGKRFTFRIVPDGKGGLTYSFRGHRFRVAQAVQDPYAQALIRGHHDYSTREVVNLAADFLEEGLGHRFPEDLFLLMMADQLEAELAVRLWQGQAGEVRPFVEFDLLPDGEGGFLLDPWPFRVDEVALDFLVYFHPYRGEEAEVVEGWGRALVGALEEGKVPEAFQEETRRVRLRPWAAEARKADDPEAFYARFGLEPTPFQREVFKVAEGDPAHLLLAPTGTGKTEAAAFPALARGERLVFVLPTRSLVDDLEGRFRRYLKILAQEEGRPKALVVDTGHRQARFRFSPDGQEEATKERHLYHADVILTTLDKLLYRYFGYAEGVKSYTFPRRIHDRRTLFVFDEVHLYEATAWANFRHLIASLYKAGVRFLVMSATMPGTYREELLLEGTLEHPPAKRPSRVLRYMPQGNPMEIIQSHRGKRVLVVLEEVKEAAELYKRLKGEGVFLYHGRLAEGQRRRVFGEVKRRDEAQEPYLLITTPAIEVGVDLDAEVLVTTLCPPENLLQRLGRVNRRGRGQGEAYVVGETYPDYLGSLPEGYLELLKALDGQDLAQGGEERLRQAIRYPKYLDPRAETFFEALQEYVYGLDLTQEPLHRKGFVATRGWTPSVRLRQGEDEVEVPIDRLVGRKEELTPVRVVERLLTDGERGNRRWEEVPLRSGELYGRELVVDYPYPYDAELGFVELPKVFQRLRHPDPQRVQLLYAPEKDAGETPEGVMDTDQVTGGGRRVLWYLGESAWAESAKSGEVAEETEEEEEEGD
>NC_017273.1|WP_081466160.1|123800_124715_+|hypothetical-protein
MPPKEERFSSATGGGRPWRRFGGWPRLLWRRTFRLWLPLPNMYAIALRIRPTSALTFRVLPGSILDIATYPFVPPTTLSGWLRRLFWAQEGLLPPDQREGNTPRFYVLPRRYLPLGAYPVGEWRVHRTHRHGPRAFTHSEFSRLRREGKPPKGGDLQLHTWEYLLAEEFLGAVLAEKEEDLRRLQGLVGYGAKLGKEGFAYLEAVGEPLEVRLEEGDAPFTPVRAEAWGGAIQGAYPLYRFRFGEAEDPDPASPDPSPVIGYEGAYFVLPRGRGLAKGFSLEGRFFAWDLVEFLWARASGGSSS
>NC_017273.1|WP_014511107.1|137004_137460_-|PIN-domain-containing-protein
MPPSPVRLHRLFLDANVLFAACWQEGRAQALLELAPRAKVLLLTSPHALEEARRNLEAKRPEALECLQRIRERVQTVPEAPMALVRKALAEGLPLKDAPILAAAWKAGAEALVTGDRRHFGHLMGRRVRGLWVVSLAEALAGVMGLLEDKG
>NC_017273.1|WP_008633599.1|137440_137683_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MELAKLSRKGQLSIPKRLLKALGVEGEAYFLVELAPEGGLLLRPAGVYPLEVYTEERLQELLAEDTLTEEERARLAALAR
>NC_017273.1|WP_014511116.1|138954_140715_-|GMC-family-oxidoreductase
MAKRLKPVDVVLVGVGWTGGILAKELAQAGYRVVGLERGHYRDTIPDFQLPWIHDELRYAVRYELMQDLSRETITFRNNRNQTARPMRVLGSFLPGEGLGGAGVHWNGVTWRFLPYDFEMRTKTLERYGPSAIPEGSTIQDWGITYEELEPYYDKFEYTCGIAGKAGNLKGVIQPGGNPFEGPRNREYPNPPMKTSYAGHLFRQAAQELGYHPFPQPSANVTQPYTNPDGVQLGACVYCGYCERFGCEVNAKASPQTTVLPVAFRTGNFELRTEAYVTRINLSPDKRQAVSVSYVDLKTGEEYEQPAEVICLTSYVLNNVRLLLLSGIGKPYDPVTGQGVVGRNYAYQAFTSVVLFFEDKVFNPFMGAGALGVSIDDFNGDNFDHGGLGFIGGGNIACSTTGARPIQSLRVPPGTPRWGAEWKKAVARYYQRNFSISFQGGVLPYRTNYLDLDPTYKDAFGLPLLRMTFDWGPNEHRASQFAAQVLERIARAIGPKTYVINRLSEHYSIVPYQSTHNTGGAVMGSDPSTSVVNKYLQSWDVPNVFVVGASAFPQNAGYNPTGTVGALAFWAADAVKRYLQRPGPLV
>NC_017273.1|WP_014511117.1|140718_141519_-|gluconate-2-dehydrogenase-subunit-3-family-protein
MNRRRFFKLVGAAAGFTVLTPGAQAQAKGHPHEAQAAPAQVSPQKPQALPVRPEAYNFFSPEEAAFVEAAVDRLIPADELGPGGREAGCAYFIDQQLAGAYGAAAKWYMGGPWGESTPQQGYQLPLTPREVYRTGIAAVNRYCQLTYGHSFAQLNPEQQDEVLRGLEAGRIDLVSLGGPPAQTFFNMLLGNTVEGYFSDPVYGGNRNKVGWRLVGFPGVAAAYVSFIENFNQPYEVEPVGIADVAGGVVDLDEHGHPIHRPLAKRR
>NC_017273.1|WP_014511118.1|142382_143474_-|IS4-family-transposase
MEQLTPLINALKRYWKADLRRLTFLAALVMALVTARTTSGPRLALSLGSIASPDPRSAYRRFQRFLAWPGLDGEGYARFIFALLRPQGLLLVMDRTEWELGKSKVNLLMLAFLYQGLAVPLFWSFLPHDGNSSTPERIALMERALAFLRAHFPHLRVEGFLADREFIGEAWFRYLEEKGIPRCIRIKANTRMWRLGSGPRAWELFASLKVGESRVPRRRYWVYGRRMWVVGLRLGVREWLIVATDLDPHRVLEVYGLRWGIERLFGALKGRGFDLEATHVTRGERLSRLLVPLSLAFVWAFRTGLVLHRVRPVRPKKHGRLGQSLFRAGLDLLTLWALALWGAGGGRRGSPLGLCPMEVLACT
>NC_017273.1|WP_041445142.1|143659_144760_+|transposase
MRPVALSLLWTILALMPTPHLRESLKALLFLFLTGHGKARPQHSKTKSPSALSRFLNRYPWPTRALIRLAREEAQKALDRARRRKGPKPRLLVVLDLVTLEKRGHFPHLPLSFFHGKWGLHLVVLYLVYGDLRVPWAYRLWRGKGEKGLSLLALSLLASLPLWMRRTFRIRVAADAAFGTAWFLFGVRRLGLETVVGMRRDRRLRGGGRLLDLRRQGSRVYLWGLSFPVWVAWYRYPLPQGGWEWRYVVATFPATPRTMLTWGRRRFTVEHFFRAAKSEFSLGQFGQRTALGVHRFLVLSLLAYLLAHWVGVEGKGSWREAREGAARVLLPELVVQVILRELHALGLGPPGGGSEGLCGVCGRCRF
>NC_017273.1|WP_014511120.1|144775_146944_+|AAA-family-ATPase
MLSPFGGEEETKAIPLEEEILLAWRVFSAALPPNFLAPVSASLHTLVREAEGKEGAELEAYAWERLEELARTSVVKDAIQSFLEVAAEKPEVLRAGLLWFRTWNRLSPEEREALYRKAERFKPTAELASKASFLQGPPPPPKPLSPSVQAARSSPPRFTPTPEQEEAVRAFLSREDMKLVAVAGSGKTTTLRLMAQSAPKERLLYVAFNRSVRDEAERTFPGNVEVLTLHGLAHRHVVRGSGAYQRKLAARNGRVTPGDVLEALELPRERYALAYVIRSTLEAFLRSASEVPTPAHIPPEYREVLQRRDKDPFSERYVLKAVRLIWKLMQDPDDSFPLSFDGFVKIWAQAGAKIRGYDAVLVDEAQDLSPVFLQVLEAHRGELRRVYVGDPRQQIYGWRGAVNAMDKLDAPERKLTWSFRFGEDLARGVRRFLAHVGSPIELHGKAPWDTEVSLARPEPPYTALCRTNAGAVEAVTSFLLEEGREGARVFVVGGVDEIAWLLRDAHLLKVGGEREKPHPELALVENWEELEELAKEVNHPQARMLVRLARRYDLLELARLLKHAQADEEGKADLVVSTLHKAKGREWDRVVLWGDFIPVWDEKVREFYRKQGALDELKEEENVVYVALTRARRFLGLDQLPDLHERFFQGEGLVKPPSVSPLSVGGAGVSADLLRELEVRVLAKLEDRLKEVAEVLAALLVEEASKAVAEAMREMGLLGEEG
>NC_017273.1|WP_014511121.1|147346_147874_-|hypothetical-protein
MSKPVVVYTDASVDTERGVGGLAVLGLVQAKGGGRFSASLSLPVEDSTLAEVMAVKLALEVVLVTLGPGTQVTLFCDNESVVEHLQNGKRNGRQDLNRALEGVARLRGLLRVTFRHKPRCSTPEMRWVDARAKEALEWARKGGPIVPGIQASKPEPSRAKPKGLLWRILRWILGG
>NC_017273.1|WP_014511122.1|147953_148760_-|hypothetical-protein
MLWDDDMGWEIEEDLDWEDREALEEYRYWLDWADGVLNQDPEPGEASEAEAEVDLLPGPELPEEVLEALAEAPLAYGWSLTEALQELEQEAGMFLEGRVRVKLHLLRLLLGLLPLAEDEPLLKLRVREDAASEPRLVPLTKGDLRRVVEGWLELYALDFPSQVYEEMKAFRRFLERSLWEKHPALAPLLLVCTALWDHLEALHDPDLDLPPWAPALVREALKRRKRALKRRFGPNDLAAFGLTQSLEESDDLYELVALEAFLGLAEGE
>NC_017273.1|WP_041445145.1|149059_150145_-|AAA-family-ATPase
MGSTSELSAAKASGGMTLEEARSFLRRLKSRRDKEEGARPILQVWQGGALSGVLLAGEVALLYGEAKVGKSRAAVALLGWPDGERAAPDSPSEDGGDAVRSRSWRVRAPLDLRFYLYHATETRYAHLRKYAQTLGAEGLTEHILPFNDVGELERALQAIQRLAEEKKAPALVVVDSLIKLVPPQQSENEAKAMDEVMARLKRAISPSEREPLVGLVVIHHATKGNSGPRGSGAIAANADHIFRLEPRREGEEDWGLLLYERGRGDVWREVEEVLRVRVRGLRRASSSSAKGVKRASKRSRESYIERARERFGGRIFSEEELFRYLTDELGLPESRARGNISLWKSREKLLSQGEGLFFKKG

Crispr_ID: NC_017273_5

• CRISPR_ID: NC_017273_5
• CRISPR_location: 172053-172528
• CRISPR_type: TypeI
• Repeat_type: I-C,III-B
• Spacer_info: 6 spacers
• Cas_protein_info: cas3,cas5,cas8c,cas7b,cas4,cas1,cas2

Consensus repeat of NC_017273_5

Consensus_repeat	Method
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	CRISPRCasFinder
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	CRT
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	PILER-CR

spacers of NC_017273_5

>5.1|172090|33|NC_017273|CRISPRCasFinder,CRT
ATAAGCGCCGCCGCGTAGAAGCCCAGCTTGGTC
>5.2|172160|38|NC_017273|CRISPRCasFinder,CRT,PILER-CR
AGGGCCCGGGCGGGGGTGGGGGGACGCCCCCCGTGGAG
>5.3|172235|35|NC_017273|CRISPRCasFinder,CRT,PILER-CR
GCGTTGGGGATGCCGCTTTCCCTTGCCCAAGCCGT
>5.4|172307|37|NC_017273|CRISPRCasFinder,CRT,PILER-CR
AAGTGTGGGGGCTGGCGGGGTGGGGGTTGGGGGCGGT
>5.5|172381|39|NC_017273|CRISPRCasFinder,CRT,PILER-CR
ATGATCTCAGGCAGCTACAGCGTCATCGCTAATGTCAAC
>5.6|172457|35|NC_017273|CRISPRCasFinder,CRT,PILER-CR
TCGCACGGCGCGGTAGAGCGCAGGATTTTCACCAG

CRISPR arrays and Neighbor proteins around NC_017273_5

CRISPR arrays

The CRISPR arrays of NC_017273_5

>merge|NC_017273|5|172053-172528|CRISPRCasFinder,CRT,PILER-CR
GTTTGTTTCCTTACCGGCCCTTTCGGGCCGGTGCAACATAAGCGCCGCCGCGTAGAAGCCCAGCTTGGTCGTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAACAGGGCCCGGGCGGGGGTGGGGGGACGCCCCCCGTGGAGGTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAACGCGTTGGGGATGCCGCTTTCCCTTGCCCAAGCCGTGTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAACAAGTGTGGGGGCTGGCGGGGTGGGGGTTGGGGGCGGTGTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAACATGATCTCAGGCAGCTACAGCGTCATCGCTAATGTCAACGTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAACTCGCACGGCGCGGTAGAGCGCAGGATTTTCACCAGGTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC

>NC_017273|5|5|172053-172528|CRISPRCasFinder
GTTTGTTTCCTTACCGGCCCTTTCGGGCCGGTGCAAC	ATAAGCGCCGCCGCGTAGAAGCCCAGCTTGGTC
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	AGGGCCCGGGCGGGGGTGGGGGGACGCCCCCCGTGGAG
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	GCGTTGGGGATGCCGCTTTCCCTTGCCCAAGCCGT
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	AAGTGTGGGGGCTGGCGGGGTGGGGGTTGGGGGCGGT
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	ATGATCTCAGGCAGCTACAGCGTCATCGCTAATGTCAAC
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	TCGCACGGCGCGGTAGAGCGCAGGATTTTCACCAG
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC

>NC_017273|5|4|172053-172528|CRT
GTTTGTTTCCTTACCGGCCCTTTCGGGCCGGTGCAAC	ATAAGCGCCGCCGCGTAGAAGCCCAGCTTGGTC
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	AGGGCCCGGGCGGGGGTGGGGGGACGCCCCCCGTGGAG
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	GCGTTGGGGATGCCGCTTTCCCTTGCCCAAGCCGT
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	AAGTGTGGGGGCTGGCGGGGTGGGGGTTGGGGGCGGT
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	ATGATCTCAGGCAGCTACAGCGTCATCGCTAATGTCAAC
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	TCGCACGGCGCGGTAGAGCGCAGGATTTTCACCAG
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC

>NC_017273|5|4|172123-172528|PILER-CR
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	AGGGCCCGGGCGGGGGTGGGGGGACGCCCCCCGTGGAG
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	GCGTTGGGGATGCCGCTTTCCCTTGCCCAAGCCGT
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	AAGTGTGGGGGCTGGCGGGGTGGGGGTTGGGGGCGGT
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	ATGATCTCAGGCAGCTACAGCGTCATCGCTAATGTCAAC
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	TCGCACGGCGCGGTAGAGCGCAGGATTTTCACCAG
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017273.1|WP_014511138.1|165469_166465_+|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|270367
NC_017273.1|WP_014511140.1|167448_167913_+|TRAP-transporter-small-permease	unknown	unknown	gnl|CDD|377284
NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
NC_017273.1|WP_014511143.1|169912_170665_+|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|377121
NC_017273.1|WP_014511144.1|170769_171990_+|ATP-binding-protein	unknown	unknown	gnl|CDD|224292
NC_017273.1|WP_014511153.1|182363_183308_+|DNA-methylase-N-4/N-6-domain-containing-protein	unknown	unknown	gnl|CDD|334588
NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NC_017273.1|WP_143829195.1|159920_161008_+|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NC_017273.1|WP_155983634.1|186201_187044_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238742
NC_017273.1|WP_014511137.1|164696_165473_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl|CDD|273839
NC_017273.1|WP_014511141.1|167909_169211_+|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl|CDD|129868
NC_017273.1|WP_014511139.1|166492_167449_+|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270320
NC_017273.1|WP_014511136.1|163936_164710_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224041
NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NC_017273.1|WP_014511155.1|187120_188101_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	gnl|CDD|187782
NC_017273.1|WP_014511142.1|169213_169900_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293815

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	6.1e-25	82.0	0.4
NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	1.1e-40	134.5	0.0
NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	4e-147	484.4	0.3
NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	2.3e-47	156.4	0.0
NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	2.4e-98	323.6	0.0
NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	8e-73	239.2	0.0
NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	3.3e-158	522.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017273.1|WP_014511138.1|165469_166465_+|transporter-substrate-binding-domain-containing-protein	gnl|CDD|270367	cd13649, PBP2_Cae31940, Substrate binding domain of an uncharacterized protein similar to ABC-type transporter for thiamin biosynthetic pathway intermediates; a member of the type 2 periplasmic binding fold superfamily. This subfamily includes the periplamic-binding protein Cae31940 which is phylogenetically similar to the ThiY/THI5 family. ThiY is the periplasmic N-formyl-4-amino-5-(aminomethyl)-2-methylpyrimidine (FAMP) binding component of the ABC transport system (ThiXYZ). FAMP is imported into cell by the transporter, where it is then incorporated into the thiamin biosynthetic pathway. The closest structural homologs of ThiY are THI5, which is responsible for the synthesis of 4-amino-5-(hydroxymethyl)-2-methylpyrimidine phosphate (HMP-P) in the thiamin biosynthetic pathway of eukaryotes, and periplasmic binding proteins involved in alkanesulfonate/nitrate and bicarbonate transport. After binding the ligand, They interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ThiY/THI5 proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.98103e-138
NC_017273.1|WP_014511140.1|167448_167913_+|TRAP-transporter-small-permease	gnl|CDD|377284	pfam04290, DctQ, Tripartite ATP-independent periplasmic transporters, DctQ component. The function of the members of this family is unknown, but DctQ homologs are invariably found in the tripartite ATP-independent periplasmic transporters.	1.166e-13
NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	2.56319e-177
NC_017273.1|WP_014511143.1|169912_170665_+|LamB/YcsF-family-protein	gnl|CDD|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	1.13785e-141
NC_017273.1|WP_014511144.1|170769_171990_+|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	3.44902e-61
NC_017273.1|WP_014511153.1|182363_183308_+|DNA-methylase-N-4/N-6-domain-containing-protein	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	6.08837e-08
NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	5.19726e-87
NC_017273.1|WP_143829195.1|159920_161008_+|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	3.03253e-36
NC_017273.1|WP_155983634.1|186201_187044_+|VWA-domain-containing-protein	gnl|CDD|238742	cd01465, vWA_subgroup, VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the VWA domain in these proteins. The members do have a conserved MIDAS motif. The biochemical function however is not known.	1.2845e-11
NC_017273.1|WP_014511137.1|164696_165473_+|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	6.65239e-70
NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0
NC_017273.1|WP_014511141.1|167909_169211_+|TRAP-transporter-large-permease-subunit	gnl|CDD|129868	TIGR00786, TRAP_transporter_permease_protein_SiaT, TRAP transporter, DctM subunit. The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family (TC 2.A.56)- DctM subunit TRAP-T family permeases generally consist of three components, and these systems have so far been found in Gram-negative bacteria, Gram-postive bacteria and archaea. Only one member of the family has been both sequenced and functionally characterized. This system is the DctPQM system of Rhodobacter capsulatus (Forward et al., 1997). DctP is a periplasmic dicarboxylate (malate, fumarate, succinate) binding receptor that is biochemically well-characterized. DctQ is an integral cytoplasmic membrane protein with 4 putative transmembrane a-helical spanners (TMSs). DctM is a second integral cytoplasmic membrane protein with 12 putative TMSs. These proteins have been shown to be both necessary and sufficient for the proton motive force-dependent uptake of dicarboxylates into R. capsulatus. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.63493e-93
NC_017273.1|WP_014511139.1|166492_167449_+|TRAP-transporter-substrate-binding-protein	gnl|CDD|270320	cd13602, PBP2_TRAP_BpDctp6_7, Substrate-binding domain of a pyroglutamic acid binding DctP subfamily of the tripartite ATP-independent periplasmic transporters; contains the type 2 periplasmic binding protein fold. DctP6 and DctP7 groups of the TRAP transporters that involved in pyroglutamic acid transport. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.78908e-134
NC_017273.1|WP_014511136.1|163936_164710_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	2.9037e-125
NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.94166e-52
NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.03066e-23
NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	3.92528e-42
NC_017273.1|WP_014511155.1|187120_188101_+|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.61431e-92
NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.01861e-89
NC_017273.1|WP_014511142.1|169213_169900_+|MBL-fold-metallo-hydrolase	gnl|CDD|293815	cd07729, AHL_lactonase_MBL-fold, quorum-quenching N-acyl-homoserine lactonase, MBL-fold metallo-hydrolase domain. Acyl Homoserine Lactones (also known as AHLs) are signal molecules which coordinate gene expression in quorum sensing, in many Gram-negative bacteria. Quorum-quenching N-acyl-homoserine lactonase (also known as AHL lactonase, N-acyl-L-homoserine lactone hydrolase, EC 3.1.1.81) catalyzes the hydrolysis and opening of the homoserine lactone rings of AHLs, a reaction that can block quorum sensing. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	8.24058e-33

Protein sequences

>NC_017273.1|WP_014511144.1|170769_171990_+|ATP-binding-protein
MERAFLPRAAGPLLERLLQVFPVVAVMGARQVGKSTLVRHLPALKGYLYLSLDDLDLRLQAEADPRALLERGDRLILDEVQRVPELLLAIKRSVDEARTPGRFVLTGSAHLLLHAHLGETLAGRAAHLVLWPMTRREQRGLGRTGPWEELLALPLQAWPSLLREARDLREDWRSAVARGGFPVPALLLKDWEERQLWLRAYLQTYLERDVPALRAVENLPELRKLMEALALRSGSLLNQSELSRDLGISQPTVHRYLNLLEVSFLLVRLRGYARSRTKRLIKSPKVYLPDPALALYLAGGRPSGAHLETLVLLDLLAFRDAQKHPPGLYYWRTASGQEVDFVLEAGEKLLPVEVKATSRPTPKDAHGLLAFLAEYPEAPGGLLLHGGEEVFPLVDRVVAAPWWAVA
>NC_017273.1|WP_014511143.1|169912_170665_+|LamB/YcsF-family-protein
MKVDLNADAGESYGAFTYGHDREIFPLVTSANLACGFHGGSPGRILEAVRLAKAHGVAVGAHPGFPDLVGFGRREMALSPEEVYADVLYQIGALSAFLKAEGLPLHHVKPHGALYLKACRDRETARAIALAVKAFDPGLPLVVLPGTVYEEEARKAGLRVVLEAFPERAYLRNGQLAPRSMPGSWITDPEEAARRALRMVLEGKVEALDGGEVEVRADTLCIHGDNPNAPEVARAVREALEQAGVEVRAF
>NC_017273.1|WP_014511142.1|169213_169900_+|MBL-fold-metallo-hydrolase
MKVIPVHTGFPGRSHRGYLGLSGAYLVVGSRLLLYDTLGFGEREGLYARLEALGVSPLDVTGVVLSHLHFDHAANADLFPWAEVYVHEAELRHAEQVAKDPRLDPACLAHLPKALPRLTAVPEGALEEGLSLLHLPGHTPGLLGLAVEGVGVLASDAVKSRFDLEGPPAPPCLDPERALKSRERLYRFPRLFPGHDVPLRREGDRFLPEGEACLEVALPHGAKVTLKL
>NC_017273.1|WP_014511141.1|167909_169211_+|TRAP-transporter-large-permease-subunit
MSLLTTGLLLVLLLFLLLLLGVYVGLALLLVGLAGLALFTTAPPGPNVATALWTSTSSWSLAALPLFVWMGEILYRSRLAQELFQGLAPLLGRLPGGLLHMNVVASALFAAVIGSSAATTATVGRFTLPELLRQGYPKALALGSLAGAGTLGFMIPPSIVMIVYGVMAEVSVARLFMAGVVPGLLLTLLFMLTVALLAHRHRKALPRGPSPASREALKGLLSVLPVLFLILLVLGSIYLGVATPTEAAAIGVAGAFLLTVLRREFGLELFRESLLGAVRTTSMIGLILAGAGVLTLAMGFTGIPRALATWAVEAGITPIALVLFLSLVYILLGWFLDGISIVVLTISVILPVVKAIGLDPLWFGVYLVLMVELAQITPPVGFNLFVLQSLSGEDLFRIARYSLPFMGVLLLMVALLVAFPGLATWLPRTMTGG
>NC_017273.1|WP_014511140.1|167448_167913_+|TRAP-transporter-small-permease
MLKGLYRLSELLALLLGLFVLLVILAQVVGRFLGFVVPSALELAGFATAGLIFLGLGPTFRAGGHIRVELLLRRLPPKARAPLGRAALGLGAAASLYAAFHLWAKTLESLRFGDLAPGLLPLPLWIPLAVVAFGMSVFAVALLEALLRSFRERP
>NC_017273.1|WP_014511139.1|166492_167449_+|TRAP-transporter-substrate-binding-protein
MKRLVTALSLLALGALAQTWNMATPYPPANFHTQNILQFVKEVEEATGGRLKITVHPGGSLFPHPQILPAVRNGQVQMGEVFMSLLANENPLFNLDSIPFVVSGYEDAWRLYQAQRPEVERWLAQRGVVFLYAVPWPPQGLYTKKPVNSAQDLKGLRFRAYNPATARLAELLGMTPVQVEAADIPQAFATGIVEAMITSPTTGVDSQAWDFARYFYDVKAWIPKNMVVIGRRAFESLSPQDREALLQAAKRAEERGWKLPQEEEAKALRTLAQRGMQVVKPSPQLMADLKKAGETMILEWQRQAGATGIRVYRQYLGR
>NC_017273.1|WP_014511138.1|165469_166465_+|transporter-substrate-binding-domain-containing-protein
MKRIGVLALAVLLAFGFAQKRVVLGVGGKTAVVYLPLTVVERLGYFKDEGLDVVIQDLQAGSRALQALVGGSVEVVMGYYDHTIQMQAQGRDIVAFVEVGRYPAIVLGVRSDLADEVKSIADLKGKRVGVTAPGSSTHFFLNYLLVKNGLKPTDVSVIGVSVGAQAVAAVQNKQVDAISNVEPAITLLQERGLIKVLADTRTTKGTREVLGGEYPAAVLYTTRAWLERNPDTAQKLVNAMVRGLRWMQGKSPEEIAQVLPEEYFLGDRDLYLKVLRNSLESFSPTGRFSETAPLRPLTVLSAFDERVKRAKIDLKRTYTNEFVDRALQNLR
>NC_017273.1|WP_014511137.1|164696_165473_+|ABC-transporter-permease
MRGLRVRLWQAGLLLGFLFLWEWASRTGRIDPFFFSLPSEIAQRVFRWFATGEIYPHLYITTVEMLLAFALGTLLGVVFGLWLALAPAVAAVLDPYVKALNAIPRVVLAPIFTLWFGLGVLSKVALGVTLVFFVAFFNTYQGVKEVSPLVLQNARLLGAKPSHLLRHVYLPAAASWIFSSLRTSIGFAVIGAVVGEYLGSAAGLGYLIAQAEGVFDTTGVFAGMVVLMAFVLVLDALVGMVERKLLVWQPKAQGGGSA
>NC_017273.1|WP_014511136.1|163936_164710_+|ABC-transporter-ATP-binding-protein
MSFLEFRRLSVAFGDYVAVEGVSLRVAEGEFVSLVGPTGCGKSTLLNAAAGLLSPSEGEVWVAGRPLKGLNPLAGYLFQQDAILPWKTALDNVALPLVFRGTPWGEARERARAWLAKVGLERFAQRFPHQLSGGQRKRVGLAQVLIADPKLLLMDEPFSALDVQTRQLMENELLRLWQEDRKTVLFVTHDLEEAIALSDRVVVMAAGPRSRPIGDFPIPLPRPRDVAEVRLTPEFLRLHREIWELLRGEVLRAHAGT
>NC_017273.1|WP_143829195.1|159920_161008_+|IS3-family-transposase
MRRWSAKEKAKIVLEVLSGQRTVAEACRAYGVAESLLYRWQREFLENAHAAFTSGCAEQEARIRELERLVGQMALELEVPKKSLGTLPAKERRELVKALKGAYPLRLLSRVLRVPRSTLYYRPQDPPPEERALRERLRALAAAWPRYGYRRLTALLRGEGVQVGEKRVRSLMREEGLLLPRKGPSPRTTFPGGLPPEGVKNPLPGLEVTRPHQVWVADLSYVVLGEGVAYLAVVMDLHTRKVLGVALGPRLSQGLTLGALEMALREGCPEVHHSDRGVQYTSRAYVERLLGLGVRLSYAGTGRPWENGHAERLIRTVKEEWVALREYRTLQEARASPLLAFKPSGLTGEPRGVYRRKELPWR
>NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'
MGRKEILRGDPLLGTLAQGFGAGYPNRFSSSTTAFAALREPPGVSARTWGSRIALIIGCMDPKAHTPNPQGAWHALKDHLEAVSRLAGGFAQHFGTPSLGQALALLHDLGKATRDFQAYLKVAAEGKRTNSVPHAVWGAALAYVALGSGQHEGWEAFGLPVMGHHAGLPKRGEAASKLAQALKEEPFKEVAAFLRSSELRTRLEGLLNEALKEVRSKTAGDPLRLDFLVRMAFSALVDADYLDTEAHFDPSVARLRQEGYSLEKLWERFHRDQEALLQRVRPSLVNSVRREVYEACLQAAELSPGLFRLTVPTGGGKTRSGLAFALRHALKHGLRRVVVAIPYTSIIDQTAQVYREILGEEAVLEHHSAYEPPLGEEQEENVLRQRLTTENWDAPLVVTTTVQLFESLFSNRPSKMRKVHRLARSVILLDEVQTLPPELLKPTLEALRLLATPVEEGGYGATVVLSTATQPTFEVIPTFQGLPVREIVPDYPRHFARLQRVVYERRPKPLSWEELSRELQTRPQVMVVLNTRKDALALLEALGEDPHAYHLSTLLCPAHRREVLEEVRRRLREGAPVRLISTQVVEAGVDLDFPEVWRAIGPLDRVVQAAGRCNREGRLDKGKVVLFWPEEGTTPRGPYRVGVEKARLLLEEYPPERLHDPGLYQAYFKELFTTVKTDKGIQEHRKDLDYPEVARRYRLIQEDTVSVVVPYGEGLARLEAFQKAPSLQNWRRLQAFVVGLFRNQVRERCGFLEAVPGFQDLYVWRGSYDPRRGLVEEYADPSDLIV
>NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5
MARLRVKVWGEYACFSRPEFKVERVSYPVPTPSAARGLLEAIFWKPEFRYEVRRIGVLRLGTPFALLRNEVGNRMGAKPFFVEDARQQRTSLVLKDVAYLVEADMVLRPHATDPLPKYLEQFERRLKKGQYHHTPYLGTREFPAYFSPPDGEVPDGGLNLDLGPMLFDLAFVEAPGRPELTFKRPGRGEVQGYALPLFFHARIREGWLEVPPEKYQELYRLEEGHAKGA
>NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MRFPPRSTRSSTGWRKAMLRELKEAFHRFRKEGVLLPLAYKRKSVSWFIRLEGGKARLEGPYGKKEGVEPVPAPDRQRSGKASEGNLKPYLLADDARYVLGLPEEGKEEEAALLHKGFKELTEKAWRETQSPHVKEVLDLLSSPELGDLREEFRQKGGKPRDLLAFKVHGVLPTELEEVQAFWARHLAEEIQGDKGYCALCGNFGPVLRIFPREVVVLGQKCQLVSFNQKAFESFGKEQAANAPLCFTCASQVVDTLDHLIRSERHSRPLYREEEGGLRNQLAVFWLSEKVEVPLETPVDLEAILGAVLSGAPVQTPPADLTQLQELLATPWTGKAWPLNLDETRFHLAVLSANKGRLVVREWFAVSLGRLKETLGRFLEGTRLVRPWGEAPHPVPVGALVQALGDGNPGLVRGLLRTAYLGTPPPHALSLAIHLLRNPKALTPEEREDWGRLHALVAALKLWLFYGKEEAKRMAELDKERKNPAYLSGRLLAVLEEAQKRASSYTLRRTLVDRFYGAASTTPAATFGVLLRLSTTAHLPKVGQELNQAVEEILSRLDEAGGFPRTLNLVGQAEFALGFYHQRAYFRANRAGKKGESGQGGS
>NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSARYLDPKKRHEFVFLFDVRDGNPNGDPDAGNLPRVDPETMHGLVTDVALKRKIRDYIALTREGKPRFAIFVQSRVALNRLILEGFQEAGIEPVSIQLAEEQMANESLLEHLDGLAEAGFSREESTLYYSGQATTEKEIAKLLMGEEEAVAPFKKELEKLAKELAKAVKGRKITEEDREKAQAKLLERFFDIRMFGAVLSTGLNAGQVRGPVQLTFARSLDPIAPLEVSITRVAITREEDRARKETEMGRKPLVPYGLYRAHGFFNPFLAAKTGVQPEDLEALWDALQNLFELDRSAARGEMTVRGLAVFSHEDGKGNAPAHRLFGLIRVERREGVEAPRSFADYRVRAPKEGSLEAHGFPGVHLAWLVRPEGLEDLPPHVG
>NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4
MWDESIPISALQHFVYCPRQCALIHLEGVWEDNLYTLRGRRAHEGVDLPEGLVREGVRVEYALPLFSERLGLVGRADVVEFHGGVPYPVEHKVGPRRARKADEVQLCAQALCLEEMLGVEVPKGALFYRASRRRREVVFTPALRAFVEETVEKVQELLRTAQLPPPVNDARCRDCSLAEACMPYLVDLVREGDS
>NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MNRLLLNTLFVQTQGAYLRLEGDTVRVEVEGAVRLQVPLHHLGGLVLFGNVLVSPFLLARCAEDGRPIVWLSEHGRFHGRLEGRTSGNVLLRRAQHQALDREEKALALAKTFVYAKVRNARLVLLRALRERGSSAPLDEALREHEAVLADLSRAKDLEEVRGLEGQAAAAYFRAFGEMLLTPEFSFTGRIKRPPRDPVNALLSFLYTLLVADAVAALEGVGLDPQVGYLHALRPGRPSLALDLVEEFRAWWADRLALTLINRRQITLKHFVERPGGAVYLSEEGRREVLTAYQRRKQEEVTHPLLKETVPIGLLLHLQARLLARYLRGDLPRYPAFLAR
>NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2
MHRLDVLVAYDVDTQSEDGQRRLRRVAQVCKNYGQRVQLSLFECRVTLAQLEDLEAKLLKIMDLEKDSLRIYVLYGGREKSLRAHGKDRYTDFDEPLIL
>NC_017273.1|WP_014511153.1|182363_183308_+|DNA-methylase-N-4/N-6-domain-containing-protein
MKRNAWEVYGEVLKTARELGLEGEEQEVTKALLAWPRERFHAFAARVGLKAKYLRHDLLPIAFLPEPLREALQGGLPLREAHRLHRLLKRGELSLQDLTGKDPKALMALPARPGEVDPRLPVWFFPPEPWEEALPMAVARALVRLYTKEGELVLDPMAGRGTVVEAARALGRRAWGGDIAPRGPLVEWADILDLPQRFRKEAALVVLHPPTFSAWLREEGYREEAEERYGEYIRHISSFLDLCRPALAPGGKLVLVARPRRALTRKDLEAGHDFFLAPWERALAEADFHPLSYHLAVSQDGRQDWHLFVGEARG
>NC_017273.1|WP_155983634.1|186201_187044_+|VWA-domain-containing-protein
MSAGVKWCALFPNCLHLLLGDRTRPRFLFLLSDGLANEGLTDLEALAREAREAARAGVYTFTLGFGEGYDRALLARMAREGGGVHRYVAEGELQGALAEELAFLKGPVNLGVRVALGGAEVHLAPFAPKEARVLLLPVGEARTLEVEERLPGGAVLYRLPLPGPAPEGSEAWREVELEALLAEGGRLLEREAASAAEAQALAEEAKELALRLQAHPLGESDRALALLTVLEAFRKAMERLAARYEAWASDRVAREGTAYAAHLSFPQRLARLRYRDRTKA
>NC_017273.1|WP_014511155.1|187120_188101_+|LacI-family-transcriptional-regulator
MPSGKPLTIRDLAKAARVSVATVSRALNGRPGVSQATRERILALAREWGFVPNAAAREMVGVATAVGILFAPGVRRHTPYFTLLLEALSEALWREGLRVAEMEVDPKGKPRQEALGYILLGAHEGDRRVEALSREGVPFVLVGVGEGIPWVAPQDVEGGYLATRHLVDLGHRTIAHLTGYPEHQAGRERLLGYRKALAEAGIPFREDLVLDGAFDPLTAYRTVRKAWEQGLRFTALFAASDEMALGAWAALEDLGVRVPEEVSLVGYDDLPEFGERLTTVRQDIPTIARKAVALLLEARDGMPPRGLRVPVRLVVRGTTRRREVGA

Crispr_ID: NC_017273_6

• CRISPR_ID: NC_017273_6
• CRISPR_location: 180589-181953
• CRISPR_type: TypeI
• Repeat_type: I-C,III-B
• Spacer_info: 18 spacers
• Cas_protein_info: cas2,cas1,cas4,cas7b,cas8c,cas5,cas3

Consensus repeat of NC_017273_6

Consensus_repeat	Method
GTTTCAATCCTCACCGGCCCTTTCGGGCCGGTGCAAC	PILER-CR
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CRISPRCasFinder
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CRT

spacers of NC_017273_6

>6.1|180626|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
AGGACGGCCATTGGAGACGCCGTCCTACCCTATCTG
>6.2|180699|39|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CCCCGCCACGTGGCGCGCAGGATGGCCCACGCCTCCCGA
>6.3|180775|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CTTGGCGCGTGGGAGGAGGTCCGGAGGGGGCTCAA
>6.4|180847|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
TCGGGGATGGTCTTACCCTCCAGAGCGGCGTGCCAA
>6.5|180920|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CTCCCCCCCCTATAGTCCCCCCCCAAAACTCGGACC
>6.6|180993|40|NC_017273|PILER-CR,CRISPRCasFinder,CRT
GATTACTCACCCTGGGTGAGTAAACTGATTGGGGGTAGGT
>6.7|181070|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
ATTCACATCGTGGGGGCGGCCACCCCCACCGTGGCC
>6.8|181143|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CGGTTGATCTCCTCCGGGGTCATGGAAGCTAAATC
>6.9|181215|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
TCCGACCTACCCGACTTCTCCCAGGAGGCCAACCGC
>6.10|181288|39|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CAGAGCAGTGTGCCAGTCTCTGGGGTGTTTGACGGGGTA
>6.11|181364|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT
GTCTACGGGAAGGCCTTCGCCCTCCGGAGGGCGGAGA
>6.12|181438|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT
TAGAAGACTCTAACGTCAGGGACCAGCTCTCCCAAACC
>6.13|181513|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CCCTCAACCTTCGCCACGCCCTCCTGGGGCGCCGG
>6.14|181585|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT
ACCAGGAGGCGTTATGACCCCACAGGAGGCCATCCA
>6.15|181658|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CAGCATGGCCTGCTCTAGGCGCGCTTCGTACTCTTCGG
>6.16|181733|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT
CTTGGCGGGAATGCCGAGCCTGGCGGCCATGAGCCGC
>6.17|181807|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT
ACGTTTCAGCTCCTCCAGGAGGTACTTCGCCGTGGCCA
>6.18|181882|35|NC_017273|CRISPRCasFinder,CRT
GTAGGGGTGGGCCGCCAGCACCAGGCCCGGGGTCG

CRISPR arrays and Neighbor proteins around NC_017273_6

CRISPR arrays

The CRISPR arrays of NC_017273_6

>merge|NC_017273|6|180589-181953|PILER-CR,CRISPRCasFinder,CRT
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACAGGACGGCCATTGGAGACGCCGTCCTACCCTATCTGGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCCCCGCCACGTGGCGCGCAGGATGGCCCACGCCTCCCGAGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCTTGGCGCGTGGGAGGAGGTCCGGAGGGGGCTCAAGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACTCGGGGATGGTCTTACCCTCCAGAGCGGCGTGCCAAGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCTCCCCCCCCTATAGTCCCCCCCCAAAACTCGGACCGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACGATTACTCACCCTGGGTGAGTAAACTGATTGGGGGTAGGTGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACATTCACATCGTGGGGGCGGCCACCCCCACCGTGGCCGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCGGTTGATCTCCTCCGGGGTCATGGAAGCTAAATCGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACTCCGACCTACCCGACTTCTCCCAGGAGGCCAACCGCGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCAGAGCAGTGTGCCAGTCTCTGGGGTGTTTGACGGGGTAGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACGTCTACGGGAAGGCCTTCGCCCTCCGGAGGGCGGAGAGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACTAGAAGACTCTAACGTCAGGGACCAGCTCTCCCAAACCGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCCCTCAACCTTCGCCACGCCCTCCTGGGGCGCCGGGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACACCAGGAGGCGTTATGACCCCACAGGAGGCCATCCAGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCAGCATGGCCTGCTCTAGGCGCGCTTCGTACTCTTCGGGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACCTTGGCGGGAATGCCGAGCCTGGCGGCCATGAGCCGCGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACACGTTTCAGCTCCTCCAGGAGGTACTTCGCCGTGGCCAGTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAACGTAGGGGTGGGCCGCCAGCACCAGGCCCGGGGTCGGTTGCACCGGCTCGAAAGGGCCGGTGAGGATTGGCCC

>NC_017273|6|5|180589-181881|PILER-CR
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	AGGACGGCCATTGGAGACGCCGTCCTACCCTATCTG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CCCCGCCACGTGGCGCGCAGGATGGCCCACGCCTCCCGA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTTGGCGCGTGGGAGGAGGTCCGGAGGGGGCTCAA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TCGGGGATGGTCTTACCCTCCAGAGCGGCGTGCCAA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTCCCCCCCCTATAGTCCCCCCCCAAAACTCGGACC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GATTACTCACCCTGGGTGAGTAAACTGATTGGGGGTAGGT
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ATTCACATCGTGGGGGCGGCCACCCCCACCGTGGCC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CGGTTGATCTCCTCCGGGGTCATGGAAGCTAAATC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TCCGACCTACCCGACTTCTCCCAGGAGGCCAACCGC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CAGAGCAGTGTGCCAGTCTCTGGGGTGTTTGACGGGGTA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GTCTACGGGAAGGCCTTCGCCCTCCGGAGGGCGGAGA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TAGAAGACTCTAACGTCAGGGACCAGCTCTCCCAAACC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CCCTCAACCTTCGCCACGCCCTCCTGGGGCGCCGG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ACCAGGAGGCGTTATGACCCCACAGGAGGCCATCCA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CAGCATGGCCTGCTCTAGGCGCGCTTCGTACTCTTCGG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTTGGCGGGAATGCCGAGCCTGGCGGCCATGAGCCGC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ACGTTTCAGCTCCTCCAGGAGGTACTTCGCCGTGGCCA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC

>NC_017273|6|6|180589-181953|CRISPRCasFinder
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	AGGACGGCCATTGGAGACGCCGTCCTACCCTATCTG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CCCCGCCACGTGGCGCGCAGGATGGCCCACGCCTCCCGA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTTGGCGCGTGGGAGGAGGTCCGGAGGGGGCTCAA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TCGGGGATGGTCTTACCCTCCAGAGCGGCGTGCCAA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTCCCCCCCCTATAGTCCCCCCCCAAAACTCGGACC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GATTACTCACCCTGGGTGAGTAAACTGATTGGGGGTAGGT
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ATTCACATCGTGGGGGCGGCCACCCCCACCGTGGCC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CGGTTGATCTCCTCCGGGGTCATGGAAGCTAAATC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TCCGACCTACCCGACTTCTCCCAGGAGGCCAACCGC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CAGAGCAGTGTGCCAGTCTCTGGGGTGTTTGACGGGGTA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GTCTACGGGAAGGCCTTCGCCCTCCGGAGGGCGGAGA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TAGAAGACTCTAACGTCAGGGACCAGCTCTCCCAAACC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CCCTCAACCTTCGCCACGCCCTCCTGGGGCGCCGG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ACCAGGAGGCGTTATGACCCCACAGGAGGCCATCCA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CAGCATGGCCTGCTCTAGGCGCGCTTCGTACTCTTCGG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTTGGCGGGAATGCCGAGCCTGGCGGCCATGAGCCGC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ACGTTTCAGCTCCTCCAGGAGGTACTTCGCCGTGGCCA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GTAGGGGTGGGCCGCCAGCACCAGGCCCGGGGTCG
GTTGCACCGGCTCGAAAGGGCCGGTGAGGATTGGCCC

>NC_017273|6|5|180589-181953|CRT
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	AGGACGGCCATTGGAGACGCCGTCCTACCCTATCTG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CCCCGCCACGTGGCGCGCAGGATGGCCCACGCCTCCCGA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTTGGCGCGTGGGAGGAGGTCCGGAGGGGGCTCAA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TCGGGGATGGTCTTACCCTCCAGAGCGGCGTGCCAA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTCCCCCCCCTATAGTCCCCCCCCAAAACTCGGACC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GATTACTCACCCTGGGTGAGTAAACTGATTGGGGGTAGGT
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ATTCACATCGTGGGGGCGGCCACCCCCACCGTGGCC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CGGTTGATCTCCTCCGGGGTCATGGAAGCTAAATC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TCCGACCTACCCGACTTCTCCCAGGAGGCCAACCGC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CAGAGCAGTGTGCCAGTCTCTGGGGTGTTTGACGGGGTA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GTCTACGGGAAGGCCTTCGCCCTCCGGAGGGCGGAGA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	TAGAAGACTCTAACGTCAGGGACCAGCTCTCCCAAACC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CCCTCAACCTTCGCCACGCCCTCCTGGGGCGCCGG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ACCAGGAGGCGTTATGACCCCACAGGAGGCCATCCA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CAGCATGGCCTGCTCTAGGCGCGCTTCGTACTCTTCGG
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	CTTGGCGGGAATGCCGAGCCTGGCGGCCATGAGCCGC
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	ACGTTTCAGCTCCTCCAGGAGGTACTTCGCCGTGGCCA
GTTGCACCGGCCCGAAAGGGCCGGTGAGGATTGAAAC	GTAGGGGTGGGCCGCCAGCACCAGGCCCGGGGTCG
GTTGCACCGGCTCGAAAGGGCCGGTGAGGATTGGCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NC_017273.1|WP_014511162.1|196520_197834_+|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|235687
NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl|CDD|188360
NC_017273.1|WP_014511143.1|169912_170665_+|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|377121
NC_017273.1|WP_014511144.1|170769_171990_+|ATP-binding-protein	unknown	unknown	gnl|CDD|224292
NC_017273.1|WP_014511161.1|195102_196527_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143404
NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NC_017273.1|WP_155983634.1|186201_187044_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238742
NC_017273.1|WP_014511157.1|189448_190555_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl|CDD|273839
NC_017273.1|WP_014511153.1|182363_183308_+|DNA-methylase-N-4/N-6-domain-containing-protein	unknown	unknown	gnl|CDD|334588
NC_017273.1|WP_014511158.1|190551_191916_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_017273.1|WP_014511156.1|188168_189401_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270451
NC_017273.1|WP_014511159.1|191919_193704_+|amylo-alpha-1,6-glucosidase	unknown	unknown	gnl|CDD|225942
NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl|CDD|350688
NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_017273.1|WP_014511155.1|187120_188101_+|LacI-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	gnl|CDD|187782
NC_017273.1|WP_014511142.1|169213_169900_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293815
NC_017273.1|WP_049780439.1|193706_195071_-|PucR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|377939

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	2.4e-98	323.6	0.0
NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	1.1e-40	134.5	0.0
NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	4e-147	484.4	0.3
NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	2.3e-47	156.4	0.0
NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	6.1e-25	82.0	0.4
NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	8e-73	239.2	0.0
NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	3.3e-158	522.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	3.92528e-42
NC_017273.1|WP_014511162.1|196520_197834_+|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl|CDD|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	2.56319e-177
NC_017273.1|WP_014511143.1|169912_170665_+|LamB/YcsF-family-protein	gnl|CDD|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	1.13785e-141
NC_017273.1|WP_014511144.1|170769_171990_+|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	3.44902e-61
NC_017273.1|WP_014511161.1|195102_196527_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	5.19726e-87
NC_017273.1|WP_155983634.1|186201_187044_+|VWA-domain-containing-protein	gnl|CDD|238742	cd01465, vWA_subgroup, VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the VWA domain in these proteins. The members do have a conserved MIDAS motif. The biochemical function however is not known.	1.2845e-11
NC_017273.1|WP_014511157.1|189448_190555_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.87924e-28
NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0
NC_017273.1|WP_014511153.1|182363_183308_+|DNA-methylase-N-4/N-6-domain-containing-protein	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	6.08837e-08
NC_017273.1|WP_014511158.1|190551_191916_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	7.47015e-77
NC_017273.1|WP_014511156.1|188168_189401_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.84382e-83
NC_017273.1|WP_014511159.1|191919_193704_+|amylo-alpha-1,6-glucosidase	gnl|CDD|225942	COG3408, GDB1, Glycogen debranching enzyme [Carbohydrate transport and metabolism].	2.95585e-81
NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'	gnl|CDD|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.94166e-52
NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.03066e-23
NC_017273.1|WP_014511155.1|187120_188101_+|LacI-family-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	3.61431e-92
NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.01861e-89
NC_017273.1|WP_014511142.1|169213_169900_+|MBL-fold-metallo-hydrolase	gnl|CDD|293815	cd07729, AHL_lactonase_MBL-fold, quorum-quenching N-acyl-homoserine lactonase, MBL-fold metallo-hydrolase domain. Acyl Homoserine Lactones (also known as AHLs) are signal molecules which coordinate gene expression in quorum sensing, in many Gram-negative bacteria. Quorum-quenching N-acyl-homoserine lactonase (also known as AHL lactonase, N-acyl-L-homoserine lactone hydrolase, EC 3.1.1.81) catalyzes the hydrolysis and opening of the homoserine lactone rings of AHLs, a reaction that can block quorum sensing. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	8.24058e-33
NC_017273.1|WP_049780439.1|193706_195071_-|PucR-family-transcriptional-regulator	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	5.01544e-32

Protein sequences

>NC_017273.1|WP_014511151.1|180097_180397_+|CRISPR-associated-endonuclease-Cas2
MHRLDVLVAYDVDTQSEDGQRRLRRVAQVCKNYGQRVQLSLFECRVTLAQLEDLEAKLLKIMDLEKDSLRIYVLYGGREKSLRAHGKDRYTDFDEPLIL
>NC_017273.1|WP_014511150.1|179075_180095_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MNRLLLNTLFVQTQGAYLRLEGDTVRVEVEGAVRLQVPLHHLGGLVLFGNVLVSPFLLARCAEDGRPIVWLSEHGRFHGRLEGRTSGNVLLRRAQHQALDREEKALALAKTFVYAKVRNARLVLLRALRERGSSAPLDEALREHEAVLADLSRAKDLEEVRGLEGQAAAAYFRAFGEMLLTPEFSFTGRIKRPPRDPVNALLSFLYTLLVADAVAALEGVGLDPQVGYLHALRPGRPSLALDLVEEFRAWWADRLALTLINRRQITLKHFVERPGGAVYLSEEGRREVLTAYQRRKQEEVTHPLLKETVPIGLLLHLQARLLARYLRGDLPRYPAFLAR
>NC_017273.1|WP_014511149.1|178494_179079_+|CRISPR-associated-protein-Cas4
MWDESIPISALQHFVYCPRQCALIHLEGVWEDNLYTLRGRRAHEGVDLPEGLVREGVRVEYALPLFSERLGLVGRADVVEFHGGVPYPVEHKVGPRRARKADEVQLCAQALCLEEMLGVEVPKGALFYRASRRRREVVFTPALRAFVEETVEKVQELLRTAQLPPPVNDARCRDCSLAEACMPYLVDLVREGDS
>NC_017273.1|WP_041445161.1|177353_178505_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSARYLDPKKRHEFVFLFDVRDGNPNGDPDAGNLPRVDPETMHGLVTDVALKRKIRDYIALTREGKPRFAIFVQSRVALNRLILEGFQEAGIEPVSIQLAEEQMANESLLEHLDGLAEAGFSREESTLYYSGQATTEKEIAKLLMGEEEAVAPFKKELEKLAKELAKAVKGRKITEEDREKAQAKLLERFFDIRMFGAVLSTGLNAGQVRGPVQLTFARSLDPIAPLEVSITRVAITREEDRARKETEMGRKPLVPYGLYRAHGFFNPFLAAKTGVQPEDLEALWDALQNLFELDRSAARGEMTVRGLAVFSHEDGKGNAPAHRLFGLIRVERREGVEAPRSFADYRVRAPKEGSLEAHGFPGVHLAWLVRPEGLEDLPPHVG
>NC_017273.1|WP_049780437.1|175545_177354_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MRFPPRSTRSSTGWRKAMLRELKEAFHRFRKEGVLLPLAYKRKSVSWFIRLEGGKARLEGPYGKKEGVEPVPAPDRQRSGKASEGNLKPYLLADDARYVLGLPEEGKEEEAALLHKGFKELTEKAWRETQSPHVKEVLDLLSSPELGDLREEFRQKGGKPRDLLAFKVHGVLPTELEEVQAFWARHLAEEIQGDKGYCALCGNFGPVLRIFPREVVVLGQKCQLVSFNQKAFESFGKEQAANAPLCFTCASQVVDTLDHLIRSERHSRPLYREEEGGLRNQLAVFWLSEKVEVPLETPVDLEAILGAVLSGAPVQTPPADLTQLQELLATPWTGKAWPLNLDETRFHLAVLSANKGRLVVREWFAVSLGRLKETLGRFLEGTRLVRPWGEAPHPVPVGALVQALGDGNPGLVRGLLRTAYLGTPPPHALSLAIHLLRNPKALTPEEREDWGRLHALVAALKLWLFYGKEEAKRMAELDKERKNPAYLSGRLLAVLEEAQKRASSYTLRRTLVDRFYGAASTTPAATFGVLLRLSTTAHLPKVGQELNQAVEEILSRLDEAGGFPRTLNLVGQAEFALGFYHQRAYFRANRAGKKGESGQGGS
>NC_017273.1|WP_014511146.1|174923_175613_+|type-I-C-CRISPR-associated-protein-Cas5
MARLRVKVWGEYACFSRPEFKVERVSYPVPTPSAARGLLEAIFWKPEFRYEVRRIGVLRLGTPFALLRNEVGNRMGAKPFFVEDARQQRTSLVLKDVAYLVEADMVLRPHATDPLPKYLEQFERRLKKGQYHHTPYLGTREFPAYFSPPDGEVPDGGLNLDLGPMLFDLAFVEAPGRPELTFKRPGRGEVQGYALPLFFHARIREGWLEVPPEKYQELYRLEEGHAKGA
>NC_017273.1|WP_155983633.1|172553_174914_+|CRISPR-associated-helicase-Cas3'
MGRKEILRGDPLLGTLAQGFGAGYPNRFSSSTTAFAALREPPGVSARTWGSRIALIIGCMDPKAHTPNPQGAWHALKDHLEAVSRLAGGFAQHFGTPSLGQALALLHDLGKATRDFQAYLKVAAEGKRTNSVPHAVWGAALAYVALGSGQHEGWEAFGLPVMGHHAGLPKRGEAASKLAQALKEEPFKEVAAFLRSSELRTRLEGLLNEALKEVRSKTAGDPLRLDFLVRMAFSALVDADYLDTEAHFDPSVARLRQEGYSLEKLWERFHRDQEALLQRVRPSLVNSVRREVYEACLQAAELSPGLFRLTVPTGGGKTRSGLAFALRHALKHGLRRVVVAIPYTSIIDQTAQVYREILGEEAVLEHHSAYEPPLGEEQEENVLRQRLTTENWDAPLVVTTTVQLFESLFSNRPSKMRKVHRLARSVILLDEVQTLPPELLKPTLEALRLLATPVEEGGYGATVVLSTATQPTFEVIPTFQGLPVREIVPDYPRHFARLQRVVYERRPKPLSWEELSRELQTRPQVMVVLNTRKDALALLEALGEDPHAYHLSTLLCPAHRREVLEEVRRRLREGAPVRLISTQVVEAGVDLDFPEVWRAIGPLDRVVQAAGRCNREGRLDKGKVVLFWPEEGTTPRGPYRVGVEKARLLLEEYPPERLHDPGLYQAYFKELFTTVKTDKGIQEHRKDLDYPEVARRYRLIQEDTVSVVVPYGEGLARLEAFQKAPSLQNWRRLQAFVVGLFRNQVRERCGFLEAVPGFQDLYVWRGSYDPRRGLVEEYADPSDLIV
>NC_017273.1|WP_014511144.1|170769_171990_+|ATP-binding-protein
MERAFLPRAAGPLLERLLQVFPVVAVMGARQVGKSTLVRHLPALKGYLYLSLDDLDLRLQAEADPRALLERGDRLILDEVQRVPELLLAIKRSVDEARTPGRFVLTGSAHLLLHAHLGETLAGRAAHLVLWPMTRREQRGLGRTGPWEELLALPLQAWPSLLREARDLREDWRSAVARGGFPVPALLLKDWEERQLWLRAYLQTYLERDVPALRAVENLPELRKLMEALALRSGSLLNQSELSRDLGISQPTVHRYLNLLEVSFLLVRLRGYARSRTKRLIKSPKVYLPDPALALYLAGGRPSGAHLETLVLLDLLAFRDAQKHPPGLYYWRTASGQEVDFVLEAGEKLLPVEVKATSRPTPKDAHGLLAFLAEYPEAPGGLLLHGGEEVFPLVDRVVAAPWWAVA
>NC_017273.1|WP_014511143.1|169912_170665_+|LamB/YcsF-family-protein
MKVDLNADAGESYGAFTYGHDREIFPLVTSANLACGFHGGSPGRILEAVRLAKAHGVAVGAHPGFPDLVGFGRREMALSPEEVYADVLYQIGALSAFLKAEGLPLHHVKPHGALYLKACRDRETARAIALAVKAFDPGLPLVVLPGTVYEEEARKAGLRVVLEAFPERAYLRNGQLAPRSMPGSWITDPEEAARRALRMVLEGKVEALDGGEVEVRADTLCIHGDNPNAPEVARAVREALEQAGVEVRAF
>NC_017273.1|WP_014511142.1|169213_169900_+|MBL-fold-metallo-hydrolase
MKVIPVHTGFPGRSHRGYLGLSGAYLVVGSRLLLYDTLGFGEREGLYARLEALGVSPLDVTGVVLSHLHFDHAANADLFPWAEVYVHEAELRHAEQVAKDPRLDPACLAHLPKALPRLTAVPEGALEEGLSLLHLPGHTPGLLGLAVEGVGVLASDAVKSRFDLEGPPAPPCLDPERALKSRERLYRFPRLFPGHDVPLRREGDRFLPEGEACLEVALPHGAKVTLKL
>NC_017273.1|WP_014511153.1|182363_183308_+|DNA-methylase-N-4/N-6-domain-containing-protein
MKRNAWEVYGEVLKTARELGLEGEEQEVTKALLAWPRERFHAFAARVGLKAKYLRHDLLPIAFLPEPLREALQGGLPLREAHRLHRLLKRGELSLQDLTGKDPKALMALPARPGEVDPRLPVWFFPPEPWEEALPMAVARALVRLYTKEGELVLDPMAGRGTVVEAARALGRRAWGGDIAPRGPLVEWADILDLPQRFRKEAALVVLHPPTFSAWLREEGYREEAEERYGEYIRHISSFLDLCRPALAPGGKLVLVARPRRALTRKDLEAGHDFFLAPWERALAEADFHPLSYHLAVSQDGRQDWHLFVGEARG
>NC_017273.1|WP_155983634.1|186201_187044_+|VWA-domain-containing-protein
MSAGVKWCALFPNCLHLLLGDRTRPRFLFLLSDGLANEGLTDLEALAREAREAARAGVYTFTLGFGEGYDRALLARMAREGGGVHRYVAEGELQGALAEELAFLKGPVNLGVRVALGGAEVHLAPFAPKEARVLLLPVGEARTLEVEERLPGGAVLYRLPLPGPAPEGSEAWREVELEALLAEGGRLLEREAASAAEAQALAEEAKELALRLQAHPLGESDRALALLTVLEAFRKAMERLAARYEAWASDRVAREGTAYAAHLSFPQRLARLRYRDRTKA
>NC_017273.1|WP_014511155.1|187120_188101_+|LacI-family-transcriptional-regulator
MPSGKPLTIRDLAKAARVSVATVSRALNGRPGVSQATRERILALAREWGFVPNAAAREMVGVATAVGILFAPGVRRHTPYFTLLLEALSEALWREGLRVAEMEVDPKGKPRQEALGYILLGAHEGDRRVEALSREGVPFVLVGVGEGIPWVAPQDVEGGYLATRHLVDLGHRTIAHLTGYPEHQAGRERLLGYRKALAEAGIPFREDLVLDGAFDPLTAYRTVRKAWEQGLRFTALFAASDEMALGAWAALEDLGVRVPEEVSLVGYDDLPEFGERLTTVRQDIPTIARKAVALLLEARDGMPPRGLRVPVRLVVRGTTRRREVGA
>NC_017273.1|WP_014511156.1|188168_189401_+|ABC-transporter-substrate-binding-protein
MKKAFLALLALLGLAFAQTQVRISGWGGTDIAIVSGLLKEVVQPKLDKEGIRVVYEPIEGDYTQWLFNALSAGTAPDLFYVDVFWSESLFATGRVEPLDAYFSKQEIAEFLPNLIQAFTYRGKLYGIPKDFNTLALQYNTDLFDEAGVAYPNQQDTWETFEAKLRQVQAKLKDVAGLCVVPDFARFGAFAFATGWKPFDEKGRTVLDKNFRRAFEWYTGLVKRGAARVAQDLGEGWTGGCFGSEKAATALEGAWIAGFLRDKAPNLPYRTTFLPLDPVTKKRGNFIFTVSWSLNAASKNKEAAVKVLKALTSPEAQQWVLERGLAIPSRKALANNPYFQRAGKEPELNRVVFQGSLAQGGHVYPFKFLAYGGDWMRPINDALQAVMTGQKSVDQALKEAQAALDRLTGRR
>NC_017273.1|WP_014511157.1|189448_190555_+|sugar-ABC-transporter-permease
MRLKARTLEALYALLLLVPFLFTLAVFFLYAFVRALYFSFTDYDLFSPPRFVGLANYLSLFRDPFFLTALGHTLAYSFVVTTLQTVLALLVAVALNQPLRGIAFFRTLYYLPSVVSTAAASLLLLWLFQRTGLVNQALSLLLGHLPHLGAFALFFLVFQTAQVFWERRRGVPVPFFDPALALLSAPLALLAAWGLGAAGVVVPREVRVEIPWLPTTATFLGIPYPLWAIILMNTYTTVPTFMVLFLAGLKGIPKTLYEAAALDGATPWTMFTRITVPLLRPVLFLVITLGLIGTLQLFDQVLFVGGSGGAPLEATITLAYYVYGNVFPSGATPRVGLASAAALFLAGLTLVIVLLQRRFGVGERGWSA
>NC_017273.1|WP_014511158.1|190551_191916_+|carbohydrate-ABC-transporter-permease
MSPREAARRRWARVAWVYGLLLAFGVFFVGPFLMGFLASLKPNPLEWPFTLRFAQVSPKNWAAAWRLGRAGSGDPWLGGMRPGREVVLEVAYFWPEDTPPPLEATVPRRRPGAGMGAVFETPYAADHVRLLGPELVEKAPAHLGEGEGYVYRFRLRVDYPGEGPFLERVPLDIQAPRGALYLGATLDPTRFERRGRVASWDNVVPGLLGYVFHNYVRAFREARSLETGESLFLRWTLNSFLLAAVKVATTLVFASMAGYALARLRFPGRQALFLFMLFSMMVPGQVTFISNYLVLRDGIFGLSKLFGVETLLNTYTGLILSGLVGAGAVFIMKQFFESIPREVEEAALIDGATPWQTLFRIVLPMSTPALGAVAILTFQGTWNEFFWPFVVLTSPREIYTLPLGLLSFRNAYGQVGDWGLILAGGFFSMVPVLILFAVFQRYFVEGVSVGALKE
>NC_017273.1|WP_014511159.1|191919_193704_+|amylo-alpha-1,6-glucosidase
MVLPLKEDDTYLVLNTRGFAEEGAEGFYRHDTRFLARYRLLLPEGLALLESRTPRPDRLIQDWARFQGPDGELYLRRSLQVERGRVREALSLHNLGRKPLEVRLGLEVEGSFEDLFQARGWSPSSRGHRGLAYRAPDGVELRVEVLPPWPLEGLTLHLAPGEVRNLGFEVRLESPLGTPGTLPSYEAFLDAFPQGEGPWAKPLRQALMDLRALLLATPEGPIPAAGIPWFVAPFGRDSLLTAFMLLPWGKEVARGVLRYLARRQGRARDPFREEEPGKILHEVRLGELSRLGKVPFARYYGTVDATPLFLVLLGRYLDLTGDLALVRELKPNWEAALAWMAAADLDGDGLLEFAPSGGGLSVHSWKDSHDSMSHKDGRLAEPPLAVSEVQGYAYAAHLAAREFYRALGEEERAREEERRAQALFALIQERFWLEELGTYALALDRRKTPLRVKASDAGHLLWAGAVPEERARKLARTLLSEELWTGWGVRTLGAKEARYNPLSYHNGSVWPHDTALFAGGLFRYGLRAEGEQVAQALLELALSQPDLRLPELVGGFPREEGLPPVPYPVACRPQAWDAAALVYLYALRKGVRAW
>NC_017273.1|WP_049780439.1|193706_195071_-|PucR-family-transcriptional-regulator
MPPEAKGQPVAGPTVAEALRHPVLARAELVGGRQGLSRRIAWVHVSELLDVARFLQGNELLLTTGMALAHASPGAREAYLSSLAERGIAALGIELVQWMRSLPGDFSAWADAAGIPLLVFREEVRFEAISQAICTLVLSRRTALLEALEEATRALLEGFAEGGLPGFAAALERLLPGQRVAVRPGPGPEEPGLWIPLTAGEEVLGVLGLVPGEGLDEVGRLVAERAAHLLAAHLAMARAQEEARRREALERLNALLLPDLFPGPPPYHPAWMGLALGEGVGEEALWPLLGEGVEAWGWRVGGARLFLLGGRRPALERVARALEGRDGVGVGPVVDGGCGARHTLREALWRLRYGQDALGLAPLLVPDPELHLAYARARLAPLLGLPPGRRRALGETLRVLLEEGNRTRAADRLGIRRQSLYRRLALLESLLGPLTPGRPDLLLALRILTEAGEL
>NC_017273.1|WP_014511161.1|195102_196527_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MLKNLIGGRWQEAHRPTLPVYNPATGEVLEEVPLSGPEEVDQAVEAASRAFPSWSQTPLTERVRLMFRFKELLEKHFEDLARLVTLHHGKTLEEARGEVRRGIEVVDFALSAPTLLQGRTLREVTRGVDQNLFHYPLGVVAGIPPFNFPVIIPLWMFPIAVVAGNTFVLKPSERTPLGAVRLAELFLEAGFPEGVLNLVHGSKEAAEALVQHPEVRAVQFVGSEPVARRIYALAAQSGKRVSAAGGAKNHLVIMPDADLDLAVPAILNSAFGNAGERCLAGSVAVGVGEVGQELLERVVEAARALKVGPGWEEGVQVGPLIREEHRRKVVAYIQRGLEEGAGLALDGRGVEGPGFFLGPTVLDRVSPRMAVGREEIFGPVLSVSYANTLEEAIRQANAVPYGNMACIFTTSGKAAREFRERVQAGMVGVNVGVAQPFAFYPFSGWKNSFFGDLHPHGPDAFLFYTQRKVVVERW
>NC_017273.1|WP_014511162.1|196520_197834_+|aminotransferase-class-III-fold-pyridoxal-phosphate-dependent-enzyme
MVDLKTLHRRHVLTPWSAQRELDPPLLVRGEGSWLYDADGRRYLDLSSGLVAVNLGHGHPRPVRAIAEQAATLAYAAPSFFHDKRALLAKALSDLAPWPEGGRVFFTPSGTEANEDALKFVRHLTGRFKVLAAYRSFHGATHGAAALTGENRRFPAEPTVPGVVHFFAPYPYRSPFFTEDPEEETRRALDHLEKVLLHEDPGRVAAIFLEPVVGSNGVIVYPEGYLKGVREICDRHGILLVFDEVMTGFGRVGEAFAALRFGVAPDLITFAKGVTSAYAPLGGVLMREGLAERFDDTPLPTGHTYSGHPLAVAAGLAALEAYREEGLFARAYRLEAALRDLLKPLEGHPLVGEVRGVGAFFGVELVRDRRTKEPLSPWHAPPSPAMKALHKALLERGVYLFAKHNVLLLAPPLTVGEEELAFGVEALKRALDELPSL

Crispr_ID: NC_017273_7

• CRISPR_ID: NC_017273_7
• CRISPR_location: 265744-265948
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: csa3

Consensus repeat of NC_017273_7

Consensus_repeat	Method
TCGGAAGACTTGGGGAGAAAGTATCGGAAGACTTGGG	CRT

spacers of NC_017273_7

>7.1|265781|20|NC_017273|CRT
GCGTCGGGGGGTGCGGGGTA
>7.2|265838|19|NC_017273|CRT
GTGTTGGCCCCCTCCCCTA
>7.3|265894|18|NC_017273|CRT
GAGAAAGGGGGCGGAGAC

CRISPR arrays and Neighbor proteins around NC_017273_7

CRISPR arrays

The CRISPR arrays of NC_017273_7

>merge|NC_017273|7|265744-265948|CRT
TCGGAAGACTTGGGGAGAAAGTATCGGAAGACTTGGGGCGTCGGGGGGTGCGGGGTATCGGAAGACTTGGGGAAAAAGTATCGGAAGACTTGGGGTGTTGGCCCCCTCCCCTATCGGAAGACTTGGGGAGAAAGTATCGGAAGACTTGGGGAGAAAGGGGGCGGAGACTCGGAAGACTTGGGGCGTTTTGCGGCCGGAAAGCCCT

>NC_017273|7|6|265744-265948|CRT
TCGGAAGACTTGGGGAGAAAGTATCGGAAGACTTGGG	GCGTCGGGGGGTGCGGGGTA
TCGGAAGACTTGGGGAAAAAGTATCGGAAGACTTGGG	GTGTTGGCCCCCTCCCCTA
TCGGAAGACTTGGGGAGAAAGTATCGGAAGACTTGGG	GAGAAAGGGGGCGGAGAC
TCGGAAGACTTGGGGCGTTTTGCGGCCGGAAAGCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017273.1|WP_014511222.1|261077_261560_+|arsenate-reductase-(azurin)-small-subunit	unknown	unknown	gnl|CDD|131741
NC_017273.1|WP_014511216.1|257790_257988_+|hemerythrin	unknown	unknown	gnl|CDD|377347
NC_017273.1|WP_014511215.1|257320_257743_+|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224870
NC_017273.1|WP_014511217.1|257984_258281_+|cupin	unknown	unknown	gnl|CDD|380358
NC_017273.1|WP_014511229.1|269966_271850_-|DUF4900-domain-containing-protein	unknown	unknown	gnl|CDD|292858
NC_017273.1|WP_014511232.1|273274_273694_-|hypothetical-protein	unknown	unknown	gnl|CDD|227305
NC_017273.1|WP_014511218.1|258277_258655_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_041445177.1|269166_269460_+|hypothetical-protein	unknown	unknown	gnl|CDD|239738
NC_017273.1|WP_155983635.1|269041_269179_+|hypothetical-protein	unknown	unknown	gnl|CDD|225296
NC_017273.1|WP_014511231.1|272798_273278_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|131575
NC_017273.1|WP_014511227.1|268041_268317_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511224.1|264226_265618_+|replication-initiator-protein-A	unknown	unknown	gnl|CDD|370826
NC_017273.1|WP_014511223.1|261571_264157_+|arsenate-reductase-(azurin)-large-subunit	unknown	unknown	gnl|CDD|274261
NC_017273.1|WP_014511219.1|258698_259796_+|hypothetical-protein	unknown	unknown	gnl|CDD|379525
NC_017273.1|WP_014511221.1|260641_260980_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
NC_017273.1|WP_014511225.1|266132_267101_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|224113
NC_017273.1|WP_014511230.1|271866_272787_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|227132
NC_017273.1|WP_041445260.1|259792_259993_-|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_041445176.1|268680_268893_+|hypothetical-protein	unknown	unknown	unknown
NC_017273.1|WP_014511226.1|267097_267985_+|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|275105

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017273.1|WP_014511221.1|260641_260980_-|transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	7.6e-21	69.4	0.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017273.1|WP_014511222.1|261077_261560_+|arsenate-reductase-(azurin)-small-subunit	gnl|CDD|131741	TIGR02694, Arsenite_oxidase_subunit_AioB, arsenite oxidase, small subunit. This model represents the small subunit of an arsenite oxidase complex. It is a Rieske protein and appears to rely on the Tat (twin-arginine translocation) system to cross the membrane. Although this enzyme could run in the direction of arsenate reduction to arsenite in principle, the relevant biological function is arsenite oxidation for energy metabolism, not arsenic resistance. Homologs to both large (TIGR02693) and small subunits that score in the gray zone between the set trusted and noise bit score cutoffs for the respective models are found in Aeropyrum pernix K1 and in Sulfolobus tokodaii str. 7. [Energy metabolism, Electron transport].	1.97406e-80
NC_017273.1|WP_014511216.1|257790_257988_+|hemerythrin	gnl|CDD|377347	pfam04405, ScdA_N, Domain of Unknown function (DUF542). This domain is always found in conjunction with the HHE domain (pfam03794) at the N-terminus.	1.37191e-11
NC_017273.1|WP_014511215.1|257320_257743_+|Rrf2-family-transcriptional-regulator	gnl|CDD|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.03141e-29
NC_017273.1|WP_014511217.1|257984_258281_+|cupin	gnl|CDD|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	3.18742e-07
NC_017273.1|WP_014511229.1|269966_271850_-|DUF4900-domain-containing-protein	gnl|CDD|292858	pfam16241, DUF4900, Domain of unknown function (DUF4900). This family consists of uncharacterized proteins around 600 residues in length and is mainly found in various Thermotoga and Fervidobaterium species. The function of this family is unknown.	4.55442e-39
NC_017273.1|WP_014511232.1|273274_273694_-|hypothetical-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	0.00655815
NC_017273.1|WP_041445177.1|269166_269460_+|hypothetical-protein	gnl|CDD|239738	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.	2.17573e-25
NC_017273.1|WP_014511231.1|272798_273278_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|131575	TIGR02523, probable_type-4_fimbrial_biogenesis_protein, type IV pilus modification protein PilV. Pilus systems categorized as type IV pilins differ greatly from one another, with some showing greater similarty to type II or type III secretion systems than to each other. Members of this protein family represent the PilV protein of type IV pilus systems as found in Pseudomonas aeruginosa PAO1, Pseudomonas syringae DC3000, Neisseria meningitidis MC58, Xylella fastidiosa 9a5c, etc. [Cell envelope, Surface structures, Protein fate, Protein modification and repair].	7.38647e-05
NC_017273.1|WP_014511224.1|264226_265618_+|replication-initiator-protein-A	gnl|CDD|370826	pfam10134, RPA, Replication initiator protein A. Members of this family of bacterial proteins are single-stranded DNA binding proteins that are involved in DNA replication, repair and recombination.	1.77795e-67
NC_017273.1|WP_014511223.1|261571_264157_+|arsenate-reductase-(azurin)-large-subunit	gnl|CDD|274261	TIGR02693, Arsenite_oxidase_subunit_AioA, arsenite oxidase, large subunit. This model represents the large subunit of an arsenite oxidase complex. The small subunit is a Rieske protein. Homologs to both large and small subunits that score in the gray zone between the set trusted and noise bit score cutoffs for the respective models are found in Aeropyrum pernix K1 and in Sulfolobus tokodaii str. 7. This enzyme acts in energy metabolim by arsenite oxidation, rather than detoxification by reduction of arsenate to arsenite prior to export. [Energy metabolism, Electron transport].	0
NC_017273.1|WP_014511219.1|258698_259796_+|hypothetical-protein	gnl|CDD|379525	pfam14256, YwiC, YwiC-like protein. The YwiC-like protein family includes the B. subtilis YwiC protein, which is functionally uncharacterized. This domain family is found in bacteria, and is approximately 130 amino acids in length. There is a single completely conserved residue G that may be functionally important.	1.48253e-10
NC_017273.1|WP_014511221.1|260641_260980_-|transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	5.08843e-17
NC_017273.1|WP_014511225.1|266132_267101_+|AAA-family-ATPase	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	7.07133e-38
NC_017273.1|WP_014511230.1|271866_272787_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|227132	COG4795, PulJ, Type II secretory pathway, component PulJ [Intracellular trafficking and secretion].	3.37606e-08
NC_017273.1|WP_155983635.1|269041_269179_+|hypothetical-protein	gnl|CDD|225296	COG2452, COG2452, Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair].	8.06613e-05
NC_017273.1|WP_014511226.1|267097_267985_+|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.38915e-38

Protein sequences

>NC_017273.1|WP_014511224.1|264226_265618_+|replication-initiator-protein-A
MARKRKQDATPPLFELELAKEPRHFDEANVARLGLISIQERIPEGYASWEEEFEVLGKPVKLACYANPNVGGVPHGLDNEVSLALIALYLNAGSPPDGTFTTTAYQILKLMGFDTSGYYYRALKESLLRLTTATYVLSEAWRADGRWQSVSFRYIDKLEFTSGKEGSLDRSSVIRITLAKEIVRSLQNRYTKPIDIEFMASLKRPLSRALYRLLDAQRLSPEREEPLARLEVGLMEWAAACKIVHKRPDKVRRTLEPAHRELIERRYLRSVEYVGRGKNQTIVYVFGEEAGGIPDAEAVNLLMAEGLSFTSAYSLARRYSLGHIKERLERYRAILEAGYRPKNRLGLLVDVIRDETGKYERPTRTRRPAKRQAAQEEAEARRLEEEAAREWAEMPREAQIRRALQVAQLVLRSRISVGELEDLSRLMESGALEPRRVVEELKEALAQDRLEGWLERFRKMLPG
>NC_017273.1|WP_014511223.1|261571_264157_+|arsenate-reductase-(azurin)-large-subunit
MALIPRRDRLPIPPKNAKVYNQVCQYCNVGCGYKVYVWPVGEEGGVKPEQNAFGLDLSTPQPPLAGQSYTETMHAVTVGRDGRQYHVVIVPAKDSPINRGNYSIRGGTNALTVWSLDRGTQDRLTYPLLRVGDQFQAITWQDALTLMGLLIKGIRDRDGNDDNIAVKCYDHGGSGQGFEDNYAAGKLFFAALSVKHIAIHNRPAYNSEVWGSRERGVHELNYTYEDARLADTIVLWGANTYETATVFYVEHMLPNIQGATVAEKQQAFDPGEPAEPGYLIVIDPRKTSSYTVAAQVAPDRVMLLRPNLGTDYILANAIARAVWEKGYYDMAYLQARTDMTLFEEYKAKSLKLSVPYDEFMAQAERITGVSRAEIEKAADWIAKPKAGRFKRRTLTIYEKGIIWNMKNYDQVAAIVQLAVLTHNIGRPGTGCGRQGGHQEGYVRPPAPTPGSIYRGGPPVNVDKFLIEGKGKFYWVIANDPYLSTPNNQVFRKRIHERTTKLTEALGAGGEPGTIQERAQKILDILYQDPDALFLVVQDIYMTETARDAHLILPAAGWGEANDTSINCNSRLLRLYEKFMDPPGEAKPDWEIFKWVGLRIAELYRAEGKFEEAKKFEFGKNWKTDEDVFLAGAEEFRDNTVSEEDEAVLEAENYKGVTYKLLKELGQKGIQTPVRRDPKTGKLVGTVRRYTYRFGTEDGKFKWYGTDDWEGYPAEVAKYLEPGMAEKYPFWVTTGRAQTIWQTAYHDRHLPEKALALPLPYVEVNPEDAKRLGLKSGDLVEVYNEEGNGTFLVYVTDAVKPGTLFLVMYHWRGTSNSLVTGYTDPKTTIPWYKGTRANLRKVAGAIPSVQQTASFLQQNKFD
>NC_017273.1|WP_014511222.1|261077_261560_+|arsenate-reductase-(azurin)-small-subunit
MTQTLTRRRFVQLTAAATALFTAGGKAQLWYAPSLTYPAVKVANLSQVKTGEPIFFNYPDASSPAVLVKLGRPAIGGVGRERDIVAFSALCTHMGCPVQYEGGRFICRCHYSMFDPAKAGQTYQGLASSWLPQIPLRIDGKGDIYAVAVAGLIWGRVKNV
>NC_017273.1|WP_014511221.1|260641_260980_-|transcriptional-regulator
MTTSLHRLEALAHPARVRIVQLLAALPDEETAKDPRCGTAYGVCFCHLKEKTGLSAPTVSHHLRILREAGLVEGVRVGRWTYYRLRPGALEAVARELLGLAQRARALEERSA
>NC_017273.1|WP_041445260.1|259792_259993_-|hypothetical-protein
MVAVWAGDGVPLPDPGWVWGAVEALRGVGAFSGLLFYPWTRPRWAEQAIKDVLPAYEEVFRRAFSP
>NC_017273.1|WP_014511219.1|258698_259796_+|hypothetical-protein
MRAASVPLKSVALPTEHGGWGFTLEPLLLGLLLSPGLPTLGLFLLGLFGFLARHPLKLLYQDLRRGKRYPRTDLALKVAGVYLVLALLGFLLAAFTARGPFLLPLLLALPLGAYMAWADAQNRARELFPEIGAALFMAAFAPAGVLAGGLPQVVALGSFLTLALRDVAALYYARTQVLRARGLKPKRHPALLALWGSALLAFLLAQGRLLPYPVFLALLLLALYGSLTLFRPPVPARVVGWTQMGFGLLVVLSAALGYTLQGLPTALLGVPAVHRLLGFALVALAFLAGVYLLVKRQVPRFARALLGLYDLNALLGLLYLAFAGKVLPHPLLALFGVALLHALIKRPHPWPGIGFLLLGLLLLWH
>NC_017273.1|WP_014511218.1|258277_258655_+|hypothetical-protein
MIPASRLALTTALLWFVAANLVGLLLGVGALPYSWRPAHAHMQLLGFVALMIYGVAYHALPRFRGVVFRRPGLALFQVGLANLGLSGMALAWGLNLGPGVWGLFAGVSFLAGALFALLMLEVLWA
>NC_017273.1|WP_014511217.1|257984_258281_+|cupin
MNLLEKARYGAVRGVELLADHPEVRLVLFSLQEGQEVRGKGEPRVHLLCLEGEGLLWAGSEEVAATPGTLLACEPGEPHGAKAGEGRFLVLGIITPRP
>NC_017273.1|WP_014511216.1|257790_257988_+|hemerythrin
MEGLTLRTTVNEILRRYPEAVELLTGLGLDTCCGGAEPLEEAAKAAGQEPEAVLRALEAFLEGRT
>NC_017273.1|WP_014511215.1|257320_257743_+|Rrf2-family-transcriptional-regulator
MALRSLLKREESYALHALLLLAEEPGLSALEIAERLKAPPAFMAKVLQKLAKAGLVESRVGRKGGVWPKLPPGEISLLKVMEALSGPVVLDLCATLKRCPTEERRGFCYLKPNLVCVNQEIRKVLASLTLKDLLPESPPA
>NC_017273.1|WP_014511225.1|266132_267101_+|AAA-family-ATPase
MKQGELVPVSEMARRLGVTRERVRQMILEGKLEGVRLGRYWYVREREGGRLRRVYTFFTHAGGAGKTSLARDLGFELARRGFRVLLVDTDPQANLTSWLGVREVAPEETLLHLVDTGQLPTPRRLSEWGLDLIPASLDLARVEVRLMQRPLSTLLLRTALRKTEGYDFVLIDSLPSLGHLAALGALAGDGLLVPVETSVKGVEALVGVMEAAQEYREALEQVDPRVPRSFVRLFVPTKFDARTLGDNRVLEKIAGLEDLAPVASPIAYRPGPHRRATERAVPLQLVGDRQAREEVERLAEEFLQRVVAQDAVREGVLEEVAE
>NC_017273.1|WP_014511226.1|267097_267985_+|ParB/RepB/Spo0J-family-partition-protein
MSRLDEVLGTAILKGKKALGKEASEVLRLPLDLLRVRGQPRRRFENLEALAESIREKGVLQPLLVRRVGEAYEVVAGERRLRAAAMAGLKEVPARVLELSDKEARLFALVENLQREDLNPYEETVGVLALLSEDLGRPVEEVVALLHRMQNERRGKATQNVLGSPEARRVEEVFKALGRMNWESFVQARLPLLSLPEDLKAALEEGAIPYTAALELKKVKDESLRKALLEEARAGLSLRELKARVRGVLRKEKAPRPWPKEVAAKLARLDLEALPPERRARVEELLAELERVLGK
>NC_017273.1|WP_014511227.1|268041_268317_+|hypothetical-protein
MLLGAGEEITPLWTPPPPGNYRALVFTASVDLTQLRRPGQAAQLDPQFNISSAWSQQTVQVQSVGTLRVVPAPDTAPVLPPEPDVVGGASQ
>NC_017273.1|WP_041445176.1|268680_268893_+|hypothetical-protein
MEEVVGLLRKMKNAKEGRVRDNVVPTAEARRVEELFKALGRMSWESFVQHRLPEDLKGSLGGVEGPGGGV
>NC_017273.1|WP_155983635.1|269041_269179_+|hypothetical-protein
MSYLTAWRWFKSGKLPVPARQLPSGTILVEEPLPEGRTVRKICFA
>NC_017273.1|WP_041445177.1|269166_269460_+|hypothetical-protein
MFRVTYARVSSADQEEDLERQVERLKAFAQAQGWAVVAEVGSATKKRGRLLQVLADPGVSRIVVEKRHHLNQFGFPLVEAALRASGRRIVVLEDECG
>NC_017273.1|WP_014511229.1|269966_271850_-|DUF4900-domain-containing-protein
MRNKGVAIVLALATVLVVSGIGALIFTRTIREIRHGAQDQGIVQTLMLARGAANLGGSLLATRGRERLERIVQQTASSTDRWAYGGNTGTEAPDPVLAAQGLANVADRFQSDLDGFLCGKNFAPDGLPAEVRVRVYVTASACGEPLPPKTRLPPGRFVEGAPRTGTGSGVSQTYALPFVMVAEASLGQARRNIVLQGEYRFTIGRSSFARYALFTNVHALSNGTGVWFTDRTLFDGPVHTNGHFRFYRSAWFGGEVTSAGCLSPGSQSCQGQTVPGAYFYGEGFVRDRNMQPSAARPSYRNRYGTHAPEFTAGVDWNASFIPLPPNSQDQRTAAQESGLYLSDDILSLKLYRKCLLGETEVACSEPLDPGVLKLQYIEVTYCVKTNKGKCTQNTTEVYRYGPDGLLYQENNRGLFVPVLRNGAPVRFNGVIYTDGEVRSLSGPERSRDTDPATAPPALAEFAQITVAAQGDIRITGDLKYEKPPCMGVPTREPDGTVTPAVCDNLGVQNVLGVYSQEGNVWIAREAPRDIHIHGTLMSSGGVVGVEGYDSIPEKGSVYLLGGIIEYYYGAFGTFDPATGRNKTGYGRAFTYDRRFLQGLAPPFFPTTGQDRVTSVSVFSYGQREQVY
>NC_017273.1|WP_014511230.1|271866_272787_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MSERRGFTLLELLLALAILATLLAVAYGGVIQFMQSRSDLDAAINAQAKLRRIVEVFTQDLRSAVFGGLSATPYPSGNASISFALIEGGAGYPVLPHDSGNNQSFKRAAEAKIVVVAGALSGVGIARGDEVLMVNNLGDGVILPVTGVNPVGGEPNRWHVVHAGCGNTIDYTPNTLLFRVRTLGFRFDPTTRRLVYREGGGEEVPVAFDMERFEIHYVYEGAFGDTVTDPPGGAFTPGYDFTRPTGAPPYQVAEVATGKTYTLRRLSLVLEARFSSRGRPVSRTYTAQVELAANTQYQAKRIVPCE
>NC_017273.1|WP_014511231.1|272798_273278_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MRKALGLTLVEVLVAIAVLSLVLVAMNAVLLSSIRQTAISGSRTQAVQILNYLGRRVVGGETALLPSSGETKVYDYGSLGTAFPDLPREVRFADPALYKAEIANQGNPNWASGLGVAVNAYRIRVCWRQAGEERCTEAYTLSAPPGGAGPAAPPLPGIN
>NC_017273.1|WP_014511232.1|273274_273694_-|hypothetical-protein
MIELLVVLAVLAVVFAIGVFNGRRTLQSQEQAAFLRSLQGLFWEAATEAASRGENLVLHFTGQRLEVRRTDGTVLRALDLPPGVSLSLTQGVVARFTPPGKVADRDGRNLRQPLSFTATVGSQTYTYTVSLIGETEVVP

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NC_017273.1	265725-265743	0	1.0

1. spacer 7.2|265838|19|NC_017273|CRT matches to position: 265725-265743, mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017273_1	1.1|102916|38|NC_017273|CRISPRCasFinder,CRT	102916-102953	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	102916-102953	0	1.0
NC_017273_1	1.2|102991|36|NC_017273|CRISPRCasFinder,CRT	102991-103026	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	102991-103026	0	1.0
NC_017273_1	1.3|103064|38|NC_017273|CRISPRCasFinder,CRT	103064-103101	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103064-103101	0	1.0
NC_017273_1	1.4|103139|35|NC_017273|CRISPRCasFinder,CRT	103139-103173	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103139-103173	0	1.0
NC_017273_1	1.5|103211|38|NC_017273|CRISPRCasFinder,CRT	103211-103248	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103211-103248	0	1.0
NC_017273_1	1.6|103286|38|NC_017273|CRISPRCasFinder,CRT	103286-103323	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103286-103323	0	1.0
NC_017273_1	1.7|103361|37|NC_017273|CRISPRCasFinder,CRT	103361-103397	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103361-103397	0	1.0
NC_017273_1	1.8|103435|36|NC_017273|CRISPRCasFinder,CRT	103435-103470	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103435-103470	0	1.0
NC_017273_1	1.9|103508|38|NC_017273|CRISPRCasFinder,CRT	103508-103545	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103508-103545	0	1.0
NC_017273_1	1.10|103583|36|NC_017273|CRISPRCasFinder,CRT	103583-103618	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103583-103618	0	1.0
NC_017273_1	1.11|103656|38|NC_017273|CRISPRCasFinder,CRT	103656-103693	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103656-103693	0	1.0
NC_017273_1	1.12|103731|35|NC_017273|CRISPRCasFinder,CRT	103731-103765	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103731-103765	0	1.0
NC_017273_1	1.13|103803|37|NC_017273|CRISPRCasFinder,CRT	103803-103839	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103803-103839	0	1.0
NC_017273_1	1.14|102916|42|NC_017273|PILER-CR	102916-102957	42	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	102916-102957	0	1.0
NC_017273_1	1.15|102991|40|NC_017273|PILER-CR	102991-103030	40	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	102991-103030	0	1.0
NC_017273_1	1.16|103064|42|NC_017273|PILER-CR	103064-103105	42	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103064-103105	0	1.0
NC_017273_1	1.17|103139|39|NC_017273|PILER-CR	103139-103177	39	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103139-103177	0	1.0
NC_017273_1	1.18|103211|42|NC_017273|PILER-CR	103211-103252	42	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103211-103252	0	1.0
NC_017273_1	1.19|103286|42|NC_017273|PILER-CR	103286-103327	42	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103286-103327	0	1.0
NC_017273_1	1.20|103361|41|NC_017273|PILER-CR	103361-103401	41	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103361-103401	0	1.0
NC_017273_1	1.21|103435|40|NC_017273|PILER-CR	103435-103474	40	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103435-103474	0	1.0
NC_017273_1	1.22|103508|42|NC_017273|PILER-CR	103508-103549	42	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103508-103549	0	1.0
NC_017273_1	1.23|103583|40|NC_017273|PILER-CR	103583-103622	40	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103583-103622	0	1.0
NC_017273_1	1.24|103656|42|NC_017273|PILER-CR	103656-103697	42	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103656-103697	0	1.0
NC_017273_1	1.25|103731|39|NC_017273|PILER-CR	103731-103769	39	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103731-103769	0	1.0
NC_017273_1	1.26|103803|41|NC_017273|PILER-CR	103803-103843	41	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	103803-103843	0	1.0
NC_017273_2	2.1|116880|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	116880-116915	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	116880-116915	0	1.0
NC_017273_2	2.2|116952|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	116952-116987	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	116952-116987	0	1.0
NC_017273_2	2.3|117024|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	117024-117059	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	117024-117059	0	1.0
NC_017273_2	2.4|117096|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT	117096-117130	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	117096-117130	0	1.0
NC_017273_2	2.5|117167|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	117167-117202	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	117167-117202	0	1.0
NC_017273_2	2.6|117239|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	117239-117274	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	117239-117274	0	1.0
NC_017273_3	3.1|128205|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128205-128240	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128205-128240	0	1.0
NC_017273_3	3.2|128277|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128277-128314	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128277-128314	0	1.0
NC_017273_3	3.3|128351|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128351-128387	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128351-128387	0	1.0
NC_017273_3	3.4|128424|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128424-128460	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128424-128460	0	1.0
NC_017273_3	3.5|128497|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128497-128533	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128497-128533	0	1.0
NC_017273_3	3.6|128570|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128570-128605	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128570-128605	0	1.0
NC_017273_3	3.7|128642|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128642-128677	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128642-128677	0	1.0
NC_017273_3	3.8|128714|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128714-128748	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128714-128748	0	1.0
NC_017273_3	3.9|128785|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128785-128822	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128785-128822	0	1.0
NC_017273_3	3.10|128859|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	128859-128894	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	128859-128894	0	1.0
NC_017273_4	4.1|136081|51|NC_017273|CRISPRCasFinder	136081-136131	51	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	136081-136131	0	1.0
NC_017273_5	5.1|172090|33|NC_017273|CRISPRCasFinder,CRT	172090-172122	33	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	172090-172122	0	1.0
NC_017273_5	5.2|172160|38|NC_017273|CRISPRCasFinder,CRT,PILER-CR	172160-172197	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	172160-172197	0	1.0
NC_017273_5	5.3|172235|35|NC_017273|CRISPRCasFinder,CRT,PILER-CR	172235-172269	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	172235-172269	0	1.0
NC_017273_5	5.4|172307|37|NC_017273|CRISPRCasFinder,CRT,PILER-CR	172307-172343	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	172307-172343	0	1.0
NC_017273_5	5.5|172381|39|NC_017273|CRISPRCasFinder,CRT,PILER-CR	172381-172419	39	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	172381-172419	0	1.0
NC_017273_5	5.6|172457|35|NC_017273|CRISPRCasFinder,CRT,PILER-CR	172457-172491	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	172457-172491	0	1.0
NC_017273_6	6.1|180626|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180626-180661	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	180626-180661	0	1.0
NC_017273_6	6.2|180699|39|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180699-180737	39	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	180699-180737	0	1.0
NC_017273_6	6.3|180775|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180775-180809	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	180775-180809	0	1.0
NC_017273_6	6.4|180847|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180847-180882	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	180847-180882	0	1.0
NC_017273_6	6.5|180920|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180920-180955	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	180920-180955	0	1.0
NC_017273_6	6.6|180993|40|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180993-181032	40	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	180993-181032	0	1.0
NC_017273_6	6.7|181070|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181070-181105	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181070-181105	0	1.0
NC_017273_6	6.8|181143|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181143-181177	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181143-181177	0	1.0
NC_017273_6	6.9|181215|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181215-181250	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181215-181250	0	1.0
NC_017273_6	6.10|181288|39|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181288-181326	39	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181288-181326	0	1.0
NC_017273_6	6.11|181364|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181364-181400	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181364-181400	0	1.0
NC_017273_6	6.12|181438|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181438-181475	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181438-181475	0	1.0
NC_017273_6	6.13|181513|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181513-181547	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181513-181547	0	1.0
NC_017273_6	6.14|181585|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181585-181620	36	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181585-181620	0	1.0
NC_017273_6	6.15|181658|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181658-181695	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181658-181695	0	1.0
NC_017273_6	6.16|181733|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181733-181769	37	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181733-181769	0	1.0
NC_017273_6	6.17|181807|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181807-181844	38	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181807-181844	0	1.0
NC_017273_6	6.18|181882|35|NC_017273|CRISPRCasFinder,CRT	181882-181916	35	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	181882-181916	0	1.0
NC_017273_7	7.1|265781|20|NC_017273|CRT	265781-265800	20	NC_006462	Thermus thermophilus HB8 plasmid pTT27, complete sequence	113638-113657	0	1.0
NC_017273_7	7.1|265781|20|NC_017273|CRT	265781-265800	20	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	265781-265800	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_CP014142	Thermus parvatiensis strain RL plasmid pTP143, complete sequence	119680-119698	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NC_005838	Thermus thermophilus HB27 plasmid pTT27, complete sequence	81077-81095	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NC_005838	Thermus thermophilus HB27 plasmid pTT27, complete sequence	81190-81208	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_AP019802	Thermus thermophilus strain HC11 plasmid pHC11, complete sequence	239088-239106	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_AP019802	Thermus thermophilus strain HC11 plasmid pHC11, complete sequence	239201-239219	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NC_017588	Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence	224549-224567	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NC_017588	Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence	224662-224680	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	265725-265743	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NC_017273	Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence	265838-265856	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_AP019795	Thermus thermophilus strain AA2-29 plasmid pAA229, complete sequence	124039-124057	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_AP019795	Thermus thermophilus strain AA2-29 plasmid pAA229, complete sequence	124152-124170	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_LR027520	Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence	184013-184031	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_AP019793	Thermus thermophilus strain AA2-20 plasmid pAA220, complete sequence	153453-153471	0	1.0
NC_017273_7	7.2|265838|19|NC_017273|CRT	265838-265856	19	NZ_AP019793	Thermus thermophilus strain AA2-20 plasmid pAA220, complete sequence	153566-153584	0	1.0
NC_017273_2	2.1|116880|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	116880-116915	36	NC_017590	Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence	17226-17261	3	0.917
NC_017273_1	1.4|103139|35|NC_017273|CRISPRCasFinder,CRT	103139-103173	35	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1391327-1391361	7	0.8
NC_017273_1	1.4|103139|35|NC_017273|CRISPRCasFinder,CRT	103139-103173	35	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1682318-1682352	7	0.8
NC_017273_1	1.4|103139|35|NC_017273|CRISPRCasFinder,CRT	103139-103173	35	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	946505-946539	7	0.8
NC_017273_1	1.4|103139|35|NC_017273|CRISPRCasFinder,CRT	103139-103173	35	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1763164-1763198	7	0.8
NC_017273_6	6.5|180920|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180920-180955	36	MN694629	Marine virus AFVG_250M263, complete genome	517-552	7	0.806
NC_017273_1	1.4|103139|35|NC_017273|CRISPRCasFinder,CRT	103139-103173	35	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	802-836	8	0.771
NC_017273_1	1.4|103139|35|NC_017273|CRISPRCasFinder,CRT	103139-103173	35	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	580580-580614	8	0.771
NC_017273_5	5.1|172090|33|NC_017273|CRISPRCasFinder,CRT	172090-172122	33	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	321205-321237	9	0.727
NC_017273_6	6.5|180920|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT	180920-180955	36	MN693764	Marine virus AFVG_250M260, complete genome	517-552	9	0.75
NC_017273_6	6.13|181513|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT	181513-181547	35	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	144869-144903	11	0.686

1. spacer 1.1|102916|38|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tggcccgggagcaacgtggacctcatccgggagaagta	CRISPR spacer
tggcccgggagcaacgtggacctcatccgggagaagta	Protospacer
**************************************

2. spacer 1.2|102991|36|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ctcaccaacggggacgtacaggagggggacctcctc	CRISPR spacer
ctcaccaacggggacgtacaggagggggacctcctc	Protospacer
************************************

3. spacer 1.3|103064|38|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

agcgccttcggcggcgaggaaatgtgcccggcgtgcaa	CRISPR spacer
agcgccttcggcggcgaggaaatgtgcccggcgtgcaa	Protospacer
**************************************

4. spacer 1.4|103139|35|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cgctctcgacttcgaccgcctcaccggcatcgggg	CRISPR spacer
cgctctcgacttcgaccgcctcaccggcatcgggg	Protospacer
***********************************

5. spacer 1.5|103211|38|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

aaggttctggaggcccacagcctggagtgcattcccta	CRISPR spacer
aaggttctggaggcccacagcctggagtgcattcccta	Protospacer
**************************************

6. spacer 1.6|103286|38|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tggccgatgcggtgaacgtttacaggggcgcgcaggcc	CRISPR spacer
tggccgatgcggtgaacgtttacaggggcgcgcaggcc	Protospacer
**************************************

7. spacer 1.7|103361|37|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtcttcctcgaccccccgtaccggggctacgaggacg	CRISPR spacer
gtcttcctcgaccccccgtaccggggctacgaggacg	Protospacer
*************************************

8. spacer 1.8|103435|36|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

aggttcgggcaagaggtggccgactacgtggaggcc	CRISPR spacer
aggttcgggcaagaggtggccgactacgtggaggcc	Protospacer
************************************

9. spacer 1.9|103508|38|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtttgcgggggggtatggggtttggggggtgagccccg	CRISPR spacer
gtttgcgggggggtatggggtttggggggtgagccccg	Protospacer
**************************************

10. spacer 1.10|103583|36|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cccgaggaggccctgcacgacctcatggtctgggcc	CRISPR spacer
cccgaggaggccctgcacgacctcatggtctgggcc	Protospacer
************************************

11. spacer 1.11|103656|38|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tgccccagtatggcgatggtcatggcccggtccgccca	CRISPR spacer
tgccccagtatggcgatggtcatggcccggtccgccca	Protospacer
**************************************

12. spacer 1.12|103731|35|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

caggtcatgggaatgtcgtagtggaccagccactc	CRISPR spacer
caggtcatgggaatgtcgtagtggaccagccactc	Protospacer
***********************************

13. spacer 1.13|103803|37|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cccacggcggctagggcctccctagcccgccccagtt	CRISPR spacer
cccacggcggctagggcctccctagcccgccccagtt	Protospacer
*************************************

14. spacer 1.14|102916|42|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tggcccgggagcaacgtggacctcatccgggagaagtagttg	CRISPR spacer
tggcccgggagcaacgtggacctcatccgggagaagtagttg	Protospacer
******************************************

15. spacer 1.15|102991|40|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ctcaccaacggggacgtacaggagggggacctcctcgttg	CRISPR spacer
ctcaccaacggggacgtacaggagggggacctcctcgttg	Protospacer
****************************************

16. spacer 1.16|103064|42|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

agcgccttcggcggcgaggaaatgtgcccggcgtgcaagttg	CRISPR spacer
agcgccttcggcggcgaggaaatgtgcccggcgtgcaagttg	Protospacer
******************************************

17. spacer 1.17|103139|39|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cgctctcgacttcgaccgcctcaccggcatcgggggttg	CRISPR spacer
cgctctcgacttcgaccgcctcaccggcatcgggggttg	Protospacer
***************************************

18. spacer 1.18|103211|42|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

aaggttctggaggcccacagcctggagtgcattccctagttg	CRISPR spacer
aaggttctggaggcccacagcctggagtgcattccctagttg	Protospacer
******************************************

19. spacer 1.19|103286|42|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tggccgatgcggtgaacgtttacaggggcgcgcaggccgttg	CRISPR spacer
tggccgatgcggtgaacgtttacaggggcgcgcaggccgttg	Protospacer
******************************************

20. spacer 1.20|103361|41|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtcttcctcgaccccccgtaccggggctacgaggacggttg	CRISPR spacer
gtcttcctcgaccccccgtaccggggctacgaggacggttg	Protospacer
*****************************************

21. spacer 1.21|103435|40|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

aggttcgggcaagaggtggccgactacgtggaggccgttg	CRISPR spacer
aggttcgggcaagaggtggccgactacgtggaggccgttg	Protospacer
****************************************

22. spacer 1.22|103508|42|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtttgcgggggggtatggggtttggggggtgagccccggttg	CRISPR spacer
gtttgcgggggggtatggggtttggggggtgagccccggttg	Protospacer
******************************************

23. spacer 1.23|103583|40|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cccgaggaggccctgcacgacctcatggtctgggccgttg	CRISPR spacer
cccgaggaggccctgcacgacctcatggtctgggccgttg	Protospacer
****************************************

24. spacer 1.24|103656|42|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tgccccagtatggcgatggtcatggcccggtccgcccagttg	CRISPR spacer
tgccccagtatggcgatggtcatggcccggtccgcccagttg	Protospacer
******************************************

25. spacer 1.25|103731|39|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

caggtcatgggaatgtcgtagtggaccagccactcgttg	CRISPR spacer
caggtcatgggaatgtcgtagtggaccagccactcgttg	Protospacer
***************************************

26. spacer 1.26|103803|41|NC_017273|PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cccacggcggctagggcctccctagcccgccccagttgtta	CRISPR spacer
cccacggcggctagggcctccctagcccgccccagttgtta	Protospacer
*****************************************

27. spacer 2.1|116880|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cctctctgccgcgagcatccttcacctccaaaggaa	CRISPR spacer
cctctctgccgcgagcatccttcacctccaaaggaa	Protospacer
************************************

28. spacer 2.2|116952|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

acctccaaaaacctgcagaggaaagagcctcaccag	CRISPR spacer
acctccaaaaacctgcagaggaaagagcctcaccag	Protospacer
************************************

29. spacer 2.3|117024|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ctacacgaagctctggaacagggggggcggtaagct	CRISPR spacer
ctacacgaagctctggaacagggggggcggtaagct	Protospacer
************************************

30. spacer 2.4|117096|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gggtctcgtccttcccgtccttcctaggcatactc	CRISPR spacer
gggtctcgtccttcccgtccttcctaggcatactc	Protospacer
***********************************

31. spacer 2.5|117167|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ggacctcgccatttccaccagggaggacgcggacta	CRISPR spacer
ggacctcgccatttccaccagggaggacgcggacta	Protospacer
************************************

32. spacer 2.6|117239|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tatcaccgacgccgccatcgtacaaaccgggagtag	CRISPR spacer
tatcaccgacgccgccatcgtacaaaccgggagtag	Protospacer
************************************

33. spacer 3.1|128205|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

attagtcacggcccaaatggccgacggcgactacga	CRISPR spacer
attagtcacggcccaaatggccgacggcgactacga	Protospacer
************************************

34. spacer 3.2|128277|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ccgtttagaaagccagcttctgagcgcccctgagggag	CRISPR spacer
ccgtttagaaagccagcttctgagcgcccctgagggag	Protospacer
**************************************

35. spacer 3.3|128351|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tcccgtggcctccagggcctcggctcctccctcgggg	CRISPR spacer
tcccgtggcctccagggcctcggctcctccctcgggg	Protospacer
*************************************

36. spacer 3.4|128424|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

aactccccggcgagatgggccacagagcgaacccctt	CRISPR spacer
aactccccggcgagatgggccacagagcgaacccctt	Protospacer
*************************************

37. spacer 3.5|128497|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cactacctagtgcaccagatgcactagtctcggggct	CRISPR spacer
cactacctagtgcaccagatgcactagtctcggggct	Protospacer
*************************************

38. spacer 3.6|128570|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gccgtgcggcgtgccgggtggtctacggccccccgc	CRISPR spacer
gccgtgcggcgtgccgggtggtctacggccccccgc	Protospacer
************************************

39. spacer 3.7|128642|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

actaccaaggggcgagaggagagatttggttcggga	CRISPR spacer
actaccaaggggcgagaggagagatttggttcggga	Protospacer
************************************

40. spacer 3.8|128714|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cccgtagccgccatttgctttccaagccaccacct	CRISPR spacer
cccgtagccgccatttgctttccaagccaccacct	Protospacer
***********************************

41. spacer 3.9|128785|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ttctcgcacccctcctcctcggcgcgtgggtccaccac	CRISPR spacer
ttctcgcacccctcctcctcggcgcgtgggtccaccac	Protospacer
**************************************

42. spacer 3.10|128859|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cagatctacctcggcccgggcgccctcgtggacccc	CRISPR spacer
cagatctacctcggcccgggcgccctcgtggacccc	Protospacer
************************************

43. spacer 4.1|136081|51|NC_017273|CRISPRCasFinder matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gatgactccaagcccattgctaaggttggttgacgactatgagttcggtcg	CRISPR spacer
gatgactccaagcccattgctaaggttggttgacgactatgagttcggtcg	Protospacer
***************************************************

44. spacer 5.1|172090|33|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ataagcgccgccgcgtagaagcccagcttggtc	CRISPR spacer
ataagcgccgccgcgtagaagcccagcttggtc	Protospacer
*********************************

45. spacer 5.2|172160|38|NC_017273|CRISPRCasFinder,CRT,PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

agggcccgggcgggggtggggggacgccccccgtggag	CRISPR spacer
agggcccgggcgggggtggggggacgccccccgtggag	Protospacer
**************************************

46. spacer 5.3|172235|35|NC_017273|CRISPRCasFinder,CRT,PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gcgttggggatgccgctttcccttgcccaagccgt	CRISPR spacer
gcgttggggatgccgctttcccttgcccaagccgt	Protospacer
***********************************

47. spacer 5.4|172307|37|NC_017273|CRISPRCasFinder,CRT,PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

aagtgtgggggctggcggggtgggggttgggggcggt	CRISPR spacer
aagtgtgggggctggcggggtgggggttgggggcggt	Protospacer
*************************************

48. spacer 5.5|172381|39|NC_017273|CRISPRCasFinder,CRT,PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

atgatctcaggcagctacagcgtcatcgctaatgtcaac	CRISPR spacer
atgatctcaggcagctacagcgtcatcgctaatgtcaac	Protospacer
***************************************

49. spacer 5.6|172457|35|NC_017273|CRISPRCasFinder,CRT,PILER-CR matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tcgcacggcgcggtagagcgcaggattttcaccag	CRISPR spacer
tcgcacggcgcggtagagcgcaggattttcaccag	Protospacer
***********************************

50. spacer 6.1|180626|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

aggacggccattggagacgccgtcctaccctatctg	CRISPR spacer
aggacggccattggagacgccgtcctaccctatctg	Protospacer
************************************

51. spacer 6.2|180699|39|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ccccgccacgtggcgcgcaggatggcccacgcctcccga	CRISPR spacer
ccccgccacgtggcgcgcaggatggcccacgcctcccga	Protospacer
***************************************

52. spacer 6.3|180775|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cttggcgcgtgggaggaggtccggagggggctcaa	CRISPR spacer
cttggcgcgtgggaggaggtccggagggggctcaa	Protospacer
***********************************

53. spacer 6.4|180847|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tcggggatggtcttaccctccagagcggcgtgccaa	CRISPR spacer
tcggggatggtcttaccctccagagcggcgtgccaa	Protospacer
************************************

54. spacer 6.5|180920|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ctcccccccctatagtccccccccaaaactcggacc	CRISPR spacer
ctcccccccctatagtccccccccaaaactcggacc	Protospacer
************************************

55. spacer 6.6|180993|40|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gattactcaccctgggtgagtaaactgattgggggtaggt	CRISPR spacer
gattactcaccctgggtgagtaaactgattgggggtaggt	Protospacer
****************************************

56. spacer 6.7|181070|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

attcacatcgtgggggcggccacccccaccgtggcc	CRISPR spacer
attcacatcgtgggggcggccacccccaccgtggcc	Protospacer
************************************

57. spacer 6.8|181143|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cggttgatctcctccggggtcatggaagctaaatc	CRISPR spacer
cggttgatctcctccggggtcatggaagctaaatc	Protospacer
***********************************

58. spacer 6.9|181215|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tccgacctacccgacttctcccaggaggccaaccgc	CRISPR spacer
tccgacctacccgacttctcccaggaggccaaccgc	Protospacer
************************************

59. spacer 6.10|181288|39|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cagagcagtgtgccagtctctggggtgtttgacggggta	CRISPR spacer
cagagcagtgtgccagtctctggggtgtttgacggggta	Protospacer
***************************************

60. spacer 6.11|181364|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtctacgggaaggccttcgccctccggagggcggaga	CRISPR spacer
gtctacgggaaggccttcgccctccggagggcggaga	Protospacer
*************************************

61. spacer 6.12|181438|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

tagaagactctaacgtcagggaccagctctcccaaacc	CRISPR spacer
tagaagactctaacgtcagggaccagctctcccaaacc	Protospacer
**************************************

62. spacer 6.13|181513|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

ccctcaaccttcgccacgccctcctggggcgccgg	CRISPR spacer
ccctcaaccttcgccacgccctcctggggcgccgg	Protospacer
***********************************

63. spacer 6.14|181585|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

accaggaggcgttatgaccccacaggaggccatcca	CRISPR spacer
accaggaggcgttatgaccccacaggaggccatcca	Protospacer
************************************

64. spacer 6.15|181658|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cagcatggcctgctctaggcgcgcttcgtactcttcgg	CRISPR spacer
cagcatggcctgctctaggcgcgcttcgtactcttcgg	Protospacer
**************************************

65. spacer 6.16|181733|37|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

cttggcgggaatgccgagcctggcggccatgagccgc	CRISPR spacer
cttggcgggaatgccgagcctggcggccatgagccgc	Protospacer
*************************************

66. spacer 6.17|181807|38|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

acgtttcagctcctccaggaggtacttcgccgtggcca	CRISPR spacer
acgtttcagctcctccaggaggtacttcgccgtggcca	Protospacer
**************************************

67. spacer 6.18|181882|35|NC_017273|CRISPRCasFinder,CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtaggggtgggccgccagcaccaggcccggggtcg	CRISPR spacer
gtaggggtgggccgccagcaccaggcccggggtcg	Protospacer
***********************************

68. spacer 7.1|265781|20|NC_017273|CRT matches to NC_006462 (Thermus thermophilus HB8 plasmid pTT27, complete sequence) position: , mismatch: 0, identity: 1.0

gcgtcggggggtgcggggta	CRISPR spacer
gcgtcggggggtgcggggta	Protospacer
********************

69. spacer 7.1|265781|20|NC_017273|CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gcgtcggggggtgcggggta	CRISPR spacer
gcgtcggggggtgcggggta	Protospacer
********************

70. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_CP014142 (Thermus parvatiensis strain RL plasmid pTP143, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

71. spacer 7.2|265838|19|NC_017273|CRT matches to NC_005838 (Thermus thermophilus HB27 plasmid pTT27, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

72. spacer 7.2|265838|19|NC_017273|CRT matches to NC_005838 (Thermus thermophilus HB27 plasmid pTT27, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

73. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_AP019802 (Thermus thermophilus strain HC11 plasmid pHC11, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

74. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_AP019802 (Thermus thermophilus strain HC11 plasmid pHC11, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

75. spacer 7.2|265838|19|NC_017273|CRT matches to NC_017588 (Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

76. spacer 7.2|265838|19|NC_017273|CRT matches to NC_017588 (Thermus thermophilus JL-18 plasmid pTTJL1801, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

77. spacer 7.2|265838|19|NC_017273|CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

78. spacer 7.2|265838|19|NC_017273|CRT matches to NC_017273 (Thermus thermophilus SG0.5JP17-16 plasmid pTHTHE1601, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

79. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_AP019795 (Thermus thermophilus strain AA2-29 plasmid pAA229, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

80. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_AP019795 (Thermus thermophilus strain AA2-29 plasmid pAA229, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

81. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_LR027520 (Thermus thermophilus isolate TTHNAR1 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

82. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_AP019793 (Thermus thermophilus strain AA2-20 plasmid pAA220, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

83. spacer 7.2|265838|19|NC_017273|CRT matches to NZ_AP019793 (Thermus thermophilus strain AA2-20 plasmid pAA220, complete sequence) position: , mismatch: 0, identity: 1.0

gtgttggccccctccccta	CRISPR spacer
gtgttggccccctccccta	Protospacer
*******************

84. spacer 2.1|116880|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NC_017590 (Thermus thermophilus JL-18 plasmid pTTJL1802, complete sequence) position: , mismatch: 3, identity: 0.917

cctctctgccgcgagcatccttcacctccaaaggaa	CRISPR spacer
cctctctgccgtgagcatcctccacctccaaaggga	Protospacer
***********.*********.************.*

85. spacer 1.4|103139|35|NC_017273|CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 7, identity: 0.8

cgctctcgacttcgaccgcctcac--cggcatcgggg	CRISPR spacer
cgatctcgacttcgaccgcatcaccacgcaatccg--	Protospacer
** **************** ****  **  *** *  

86. spacer 1.4|103139|35|NC_017273|CRISPRCasFinder,CRT matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.8

cgctctcgacttcgaccgcctcac--cggcatcgggg	CRISPR spacer
cgatctcgacttcgaccgcatcaccacgcaatccg--	Protospacer
** **************** ****  **  *** *  

87. spacer 1.4|103139|35|NC_017273|CRISPRCasFinder,CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.8

cgctctcgacttcgaccgcctcac--cggcatcgggg	CRISPR spacer
cgatctcgacttcgaccgcatcaccacgcaatccg--	Protospacer
** **************** ****  **  *** *  

88. spacer 1.4|103139|35|NC_017273|CRISPRCasFinder,CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 7, identity: 0.8

cgctctcgacttcgaccgcctcac--cggcatcgggg	CRISPR spacer
cgatctcgacttcgaccgcatcaccacgcaatccg--	Protospacer
** **************** ****  **  *** *  

89. spacer 6.5|180920|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to MN694629 (Marine virus AFVG_250M263, complete genome) position: , mismatch: 7, identity: 0.806

ctcccccccctatagtccccccccaaaactcggacc---	CRISPR spacer
agaccccccctatagtccccccccaagact---accaag	Protospacer
   ***********************.***   ***   

90. spacer 1.4|103139|35|NC_017273|CRISPRCasFinder,CRT matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 8, identity: 0.771

-cgctctcgacttcgaccgcctcaccggcatcgggg	CRISPR spacer
gcgc-ctcgacttcgagcgcttcaccggcaacaccc	Protospacer
 *** *********** ***.********* *.   

91. spacer 1.4|103139|35|NC_017273|CRISPRCasFinder,CRT matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 8, identity: 0.771

-cgctctcgacttcgaccgcctcaccggcatcgggg	CRISPR spacer
gcgc-ctcgacttcgagcgcttcaccggcaacaccc	Protospacer
 *** *********** ***.********* *.   

92. spacer 5.1|172090|33|NC_017273|CRISPRCasFinder,CRT matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 9, identity: 0.727

ataagcgccgccgcgtagaagcccagcttggtc	CRISPR spacer
agcagcgccgcctcgtaggagcccagccgcgag	Protospacer
*  ********* *****.********.  *  

93. spacer 6.5|180920|36|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to MN693764 (Marine virus AFVG_250M260, complete genome) position: , mismatch: 9, identity: 0.75

ctcccccccctatagtccccccccaaaactcggacc	CRISPR spacer
agaccccccctatagtccccccccaagactactaag	Protospacer
   ***********************.***   *  

94. spacer 6.13|181513|35|NC_017273|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.686

ccctcaaccttcgccacgccctcctggggcgccgg	CRISPR spacer
tgcggcgatttcgccacgccctcctggagctccga	Protospacer
. *   . .******************.** ***.

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	13556 : 23423	9	Staphylococcus_phage(33.33%)	tRNA,transposase	NA
DBSCAN-SWA_2	89674 : 150987	46	Cafeteria_roenbergensis_virus(25.0%)	integrase,transposase	attL 130250:130283|attR 161598:161631
DBSCAN-SWA_3	350853 : 396075	42	Planktothrix_phage(40.0%)	protease,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017273|13556:23423|DBSCAN-SWA
CTCACCCTATTTGGCTGAGGGCCTCGCGGATCCTTTCCGCCTGCTCCAGGTTCTCCTTAAGCCTGGCCTCCTCCGCCGCCACCACCTCCTTGGGGGCCTTCTCCCGGAAGCTGGGGGCGGCAAGCTTCCTCTGGCTCCTTTCCGCAAGGGAGAGGAGCTCCTTGAGCCGCTTCTCCTGGCGTTTTTTCCACTCTTCCACGTCCAGAAGGCCTTCTAGGGGCATGCGGACGGTAACTTTGGGCATGGCCTTGACCAGGGCCTTTTCGGGCCTTTCGGGGAGGAGCTCGGCCCGGGCCAGGAAGCGGAAGGCCTCGAGGTTCTCCCGCACGGGGGCCGTCTCCCCCTCCAGAAAGACCCGCACCTCCTGCCCCGGGGGAAGCCCGGCCTCGGCCTTCAGGGCCCGCACCGCCGTCACCGCTTGCTTTAGGGCCTCAAAGGCCCTCTCGGCCTCCTCGTCCCTCTCTCCAGGCTCGGGCCAGGCCTCGAGGGCGAGTTCCTCCTTGCCGGTGAGGGCCTGGAAAAGCTCGCTGGTGATAAAGGGCATCATGGGGTGGAGGAGCTTGAGGAGGGTGGCGAGGGCTTCCTCCAGGGTCCTTAGGGTGTGGGCGTTTCCCGCCTTGAGGGCGGGCTTGGCCGCCTCCAGGTACCAGTCGCAGAACTCGCTCCAGACGAGCTCGTAGACCTCCCGGGCCGCCTGGGCCAGGTCCAGGGCCTCGTAGAGGGCGGTGATCTCCTCCACGCCCCGGCTTAGGCGGCTTCGCATGAAGCGGTCCGCCAGGGTGGGGGCGTCCTCCTTGGCCTGGAAGCCTTCCCGGGAGAGGAGGACAAAGCGGGCGGCGTTATAGAGCTTGTTGGCGAAGTTGCGGGCCATCTCCAGCCAGCGGGGGTCTAGCCTTATGTCCTGTCCCCCCGTGGCCAAATAGAGGAGGGCGAAGCGAAGGGCGTCGGCCCCGTAGCGCGCCACCAGCTCCAGGGGGTCTATCGTGTTCCCCTTGGACTTGGACATCTTCTGGCCCTTTTCGTCCAGGAAAAGGCCGTGGAGGAGCACGGTCTTGAAGGGCCTTTCCCCCATGAAGTGGTAGCCGGAGACCTCCATGCGGGAGACCCAGAGGAAGAGGATGTCGTACCCCGTGACCAGGACGTCCCCGGGGTAGAAGGCCTTGAGGTCCTCCGTTTCCTCGGGCCAGCCCAGGGTGGAAAGGGGCCAAAGGGCCGAGGAGAACCAGGTGTCAAAGACGTCCTCGTCCCGCCTGAGCCTCGGGCTTCCGCAGGCCTCGCAGTGGGTGGGGTCTTCCAGGTAGCGCTCGGGGCGCGGGACGTTGATGGCGCCGCAGTCCTCGCAGTACCAGGCGGGGATCTGGTGGCCCCACCAAAGCTGGCGGGAGATGTTCCAGTCCTTGACGTTCCTGAGCCAGTCCAGGTTGACCTTCTTCCAGCGCTCGGGCACGAAGGCGATGTCCCCCCGCTCCAGGCCCCTTATGACCTTTTCCGCCAGGGGCTTCATGGAAAGCCACCACTGGGGGAAGATGGCGTACTCAATGGGGGTGCCGCAGCGGGAGCAGGTGGCGAGGGCGATGGTGTAGTCCTCCTCCTTCACCAGGTGCCCCGCCTCCCGGAAAAGCTCCACCGCCTTCCTGCGGGCCTCAAAGCGGTCCAGGCCCCTGAGGGCCTCGGGTACCCGCTCGCCTTCCATCTTCCCTTCCAGGTTGATGACGGAAACGGGCTCTAGGCCGTGCCGCTCCCCGATCTCGTAGTCCAGGGGGTCGTGGGCCGGGGTGACCTTGAGGGCCCCGGTGCCGAACTCCTTCTCCACGGCGGGGTCGGCGAGGATGGGGATCCAGATCTCCGTGAGGGGGATCCGGGCCCTTTTGCCGATGAGGTGCCGGTAGCGCTCGTCCTCGGGGTGGACGGCGATGGCCTGGTCGGCGAAGACGGTTTCGGGACGGACGGTGGCGATCTCAATGAAGCCACCCCCCTCCACCTCGTAGCGCAGGGTGTAGAGCTTGCCCGGGGTGGGCTCGGTTTCCACCTCGAGGTCGGAAAGCGTGGTCTCGCACCGGGGGCACCAGTTCACGAGGCGGGGCGCCCGGTAGGCCAGGCCCTCGTGGTAGTAGCGGGAAAAGGCGTAGCGCACCGCCTTGGAGCGCTTCTCGTCCATGGTGAAGGCCTCCCGGCTCCAGTCGGCGCTGGCCCCCAGGCGCTTGAGCTGCTGGAGGATGGTCCCCCCCGACGCCTCCTTCCACTCCCAAACCCGCTTTAGGAAGGCCTCCCGGCCCAGGTCGTGCCGGGTTTTGCCCTCCTTGAGGAGGAGGCGCTCCACCACCACCTGGGTGGCGATCCCGGCGTGGTCGGTGCCGGGAAGCCACACCGCCTCAAACCCCCGCATGCGCTTGTAACGGATGAGGGCGTCTTGGAGGGAGTTGTCCAGGGCGTGGCCCATGTGGAGGCTTCCGGTGACGTTCGGGGGCGGCATGAAGATGACGAAGGGGGGTTTGCCGCTTTTGGGGTTCGCCACGAAGGGGTTCTTCGCCCACTTCTCCGCCCACTTGGGCTCCACGGACTGGGGATCGTAGGTCTTGGGTAGGTCCATGCCCCTTACTTTAGCGGATGGCCTAAGGAGGCCACAACCATAAGTATCCTCCCCTAATATTTTCGACTCCATACCCCTAGGGCAGACTGGCCTTGCCTAGTAAATTGCCTTGGGATATGGACCCCCTAGACTAGACGATGATTTAGATGTAGGACGACCCCATCCGGGAGATCAAGATGAAGAAGCCCAAAGCGGTACCGCCACAAGTGAAGTTTCAAGCCGCTCTGGAGGCCATCAAGGGGGAGAAGAGCCTGGTGGAACTCGCCCGCATCTACAACGTCCACCCCAACACCATCCTGAAGTGGAAGGCAGAGCTTATGGAGAAGGGGGCCACCGTCTTCTCCAACGAGACCCAGGAGAAGGAGCTGGAGAAGAGGATCCGCGACCTGGAGCAGCTCATCGGCAAGAAGGAAGTGGAGATCGCCCTCCTAAAAAAGCCGAACCTACGCTTCGCGTGACCCTCGGGCAGGGGAGGTGAAGCGGATGACCCTGGGCGAGCGCATCGGCCTGGCCCGCGAGGCGCTGGCCCAGGGTTTAGCTCCCCTGCCCATCGTCCTCAGGGCCCTGGAGATCCCCCGGGCCACCTGGTACTACTACCAGAAGCAGAAGGTGGCGGCGGACCGGAAGCGGGAGGAGGAAGACCTCCGCCTCAAAAGGGCCATGAAGAAGGTCTTGCTGGAACACCCCGAGTACGGCTACCGCCGGGTCACCGAGGCGCTCAAGAGGAAGGGTATCCCGGTCAACCATAAACGGGTCCACCGTCTGTTGCAGGACTTCCACCTCTCCCTGAAGCGCACCGCCCGGAGGCCCAAGCCCAACCCCCTGCTGCAGATCGTGCTTTTGGCCGGGGACAAAGCGGACCTGAGGGCCTCCCTTCTCCGGGAGAGGGAGCCGGAGCCCTTTGCGCTTCTGTACACCGACTTCACCCTTCTGCCCTACCGGGGAGGGAAGGCCTGGTTCGTGCCCATCCTGGACCATAGGACGCGGATGGTGGTGGCTTTTGGTCTAGGCCCGTCCCCTTCGGCGGAGCTGGCCCTGGAGGCCTGGGCGGAGGCCAAGGCTTTTCTCCGGACCCGGGTGGGAGGGCTCCCCAGGGTTCTGGTCCACCACGATCAGGGGGGTCCTTTTCTGAGCCACGACTGGGTGGGGACGCTTCTTAGGGAGGGGCAGCGGCTTTCCTACAGCCTGATGGGGGCGAAGGGTAACCCGGTGGTGGAGAGCTTTTTTGCGCGGTTCAAGGCGGAGGGGGGAGACCAGTTCTTGGAGGCCAAGAGCCTTGGGGAGCTAAGGGGGGTGGTGGAGGAGCGGCTACGCTACTACCACGAGAGCCGGTTGCACTCGGGGCTAGGCTACCGAACGCCGAGGGAGGTGATGGAGGAGGCGCTGGGAAAGACCTGGGAGGCGTCACACGGGAGGCAGGGTGAAGGTGTCTAAGTTCAGGGGGCCGGATCAGCTAGCCCACGTGCCGCAATCGGAGCGGGAGGCGGTAGCGGAGGAGCTCAAGGAGGTTTTCACGGTGAAGCGGCGGAGCACCGCTGAGTCCTTAGCCCAAGGTTTCATGGAGCGCTACCGGGAGCGGTATAGGCGGGCGGTGGAGGTGTTTGCCCAGGGGATAGAGGAGGCGTTGACCTATCTGGAGTTTCCTGGTAGCCACCAGGGGCAGATCAAGAGCACGAATGTGCTGGAGCGGCTTTTCCGGGAGGTGAAGCGGAGGACCAAGGTGGTGGGGGTATTCCCGAGCGAAAAGAGCCTGGCCAACCTGGCCACGGTGGTGATGCTCAGGGCCAGTGAGGACTGGGCGTTCAGGCGCTACATGGACATGGGCCCCCTCTGGGCCGCGGAGGAGAAACCCACAAAAAAGGCTACTTGACCTGGGGGTTTGAGGTAGCACACGAAGGCATTTCATTTGCGGCTCCTTCTGCGTCGTTAATGGCAAGAGCTAGGCCTTAGTTAGGCTGATTATGGGGTCGGGGATCAAGCAACTAAGGGCTTGGTCCTCGGCCCCAATGCGGAGCTTCCTACATCGGTCATCTAGCTCTCTCATAGGGAGGAAAGTATGGCTTATCTACGCCAATTTTTCGCGGAGATTTGGCTCAACTTGAACTTTTACCGGATTTATTGGCCCGACTTCTTGGCCGGTCTCTTTGCGGATATGGCGTTTTTTTACGCCATATGGATGGCCCTGGGATCGGTCGTCGTGTCTAACCCGAGCGCCGACCTTGGCGGAGGGCAGAACATCCTCTTCATGTATGCCGTCTTTGGCATAGTGGTGGGCATTTTTCAATCTGTGGCCTTCACGGTCGCCCAGGAAGCTCAGAGGGGTACGCTAGAACACTTAGCCTTGGCCCGGGGGGGTCTTGTGGTCCAGCTTCTCTTTAGGGGAGCATCGGATAGCTTGTTTATCCTGTTTAGGACGGGCGTTTTGTTGGGGGTTCTGTTGGTGCTGACGGGCGCTTCTTTCAATCCGAAACCCTTCTGGCTGCTTGCCCTGGCACTTTTGGTGGTATCAGCCTTGGGGTTTTCCCTGAGTATGGCTGCCCTCGCCCTCTACTTCAAGAAGATTCTAAGCTTTTTTACCATCATCCAGTTTAGTCTCTTGCTCTACTTCTTTTCGGTAAACCATTGGAGAGATTACATGGTGTACCTTCCCCTGGCCCCAGCTGCACACCTCTTGAGCCGAAGCTTTTCCGGGGGAGGCGAGTGGACAGAGTGGGTGGTCCTTTCTGCTTTTCTGCAGGCTTTGCTGTTCGTATGCTTCGGCCTTCTGGCCTTAGGCTACACGCATAGGTTGGTCCGTCTGCGGGGGATTTTAGGGAGGTACTGATGCGGCTTTTGGTGCAGAACGTCCACAAGCGCTTCGGGAAACTGGAGGCCCTCAAGGGGGTGAGCCTGGAGCTTGGGGCCGGGGAGATCCTGGGCCTTTTGGGCCCCAACGGGGCGGGCAAGACCACCCTCATCAAGGTCGTCCTCGGACTTCTCCTGCCCGATGGGGGGGAGGTGGTCCTGGAGGAGGACGGGGCGCGGCGCAGGCCCCAGGGCCACGAGTTCGGCGTCCTCCTGGAGGGAAGCCGCAACCTCTACGTCAACCTGAGCCTCCTGGTGAACGCCCTCTACTTCGGGGGCATCCGGGGGCTTCCCCCTAAGGAGGTCCGCCCCCGGTTTGAGGCCTGGCTGGAGCGCTTCGGCCTAAAGGACCGCCTCCACGCCCCCCTCGCCTCCCTCTCCCGGGGCATGCAGCAGAAGGCGGCCTTGGCCCTGGCCCTCGCCCTCAAGCCCCGCTTCCTCCTCCTGGACGAGCCCACCCTGGGCCTGGATCCCGTGAGCCGGAGGGAGTTTGAGGGGATCCTCCTGGAGCTTAAGAAGGAGGGCTGGGGCATCCTCCTCACCTCCCACGACCTCGAGGTGGTGGAGCGGGTGAGCGACCGCGTGGCCTTCCTCCACCGGGGGGAGGTGCGGCGGCAGGGCCCCACCCGGGCCCTCCTCCGGGACTGGGCCGGGGAGGGGTACCGGGTGCGCCTCGCCGAGCCCAAGGCGGAGGCCCTCCTCCAGGCCTTAGGCCCCGGCTGGAGCGCCGAGGGCCCCGAGGTCCTCTTCTTCCTCGGGCCGTGGGAGGCGCTGCGGGAGGTCTTGGGAAGGCTTCCCGTGGAGGTCCTCGAGGTCTCCAGGGGAACGCCGAGCCTGGAGGCCCTCTTCCTCCACCTCTTCGGGGAGGCCCGCCCTTCCCCTGGCGCACAACCTCGCACTGTCTAGCCGCACGGGGGATAGGGGGGTGTTGCCGGTCCTCGAGGGGGTCGGCGAGGGACCGCCCCCCACCCGGGTCGGCCCAGGGGATTGGCCCAAAAACGCGATGGCGGAAGGGCCTCTCGAGGCGCCCCCCCTTCCCGTTGACCCCTTACCCAACCTGTGGTAGGGTCTTGGGCAGGACGCCCAAGACTTAGGGTGTCCTGGCCGCGATGCCAGGCCGACAGGCCTGGACGCCCAGAGGCGGTGGGGGAAGTCCGGTGAAAGTCCGGCGCTGTCCCGCAACGGTAACCGGCCCAAGCGTCGCGCCCTCCGCCCCGGCCGGAAGCCCGAGTACCCGCTTCGCGGCCCTGCCCCGTAGCCCTCGAGGCAAGGGTGAAGGTGGTGAGACCCGTGGGACCTTAGCCTAACCCCCTAAAACCCGTCACGGGCCCAGCGCCCGAAAGAGGCCCTTCGGCTCTAGGAAGCTTTTCCCGCCCAAGGAGGCGCTATGCGGGAGACGCGGATGGTCTACCCCGTCTTCCCCGGGGAGACCAACCACTACGGAACCCTGTTTGGCGGAACGGTTCTGGCCTGGATGGACCAGGCGGCCTTTGTGGCCGCCACGCGCCACGCGCGCAAGAAGGTGGTAACGGTACACGCGGACGCGGTGGACTTCAAGCGCCCCGTCCCCCTGGGGGCCATCGTGGAGCTGGTGGCCCGGGTGCGGGAGGTGGGGCGCACCTCCATGCGGGTGGAGGTGGAGATGTGGGTGGAGCCGGTGAAGGAAGGCGAGGAGGCCTACCTGGCCGCCCGGGGCGGGTTTGTCCTGGTGGCGGTGGACGAAAGGGGGAGGCCAAGCCCGGTGCCTCCCCTGGAAGGAGGTGAGGCCCGTGCCCCTCACGGCGCCTAGGCTCGCCTACCGCCCCTACGAGTACCCCGAGCTCCTCCGCTTCCGGGACGCCATCCGGCACAGCTACTGGGTGCACACGGAGTTCAGCTTCCAGTCCGACCTCCAGGACCACGCCCTGGCCGACGAGAAGGAGCGCTCCCTGGTGGAGCGCGCCCTCCTCGCCATCGCCCAGGTGGAGCTCGCCGTCAAGCTCTTCTGGGCCCGGGTCTACGACCGCTTTCCCAAGCCCGAGATCGCCGAGGTGGGCCTCACCTTCGCCGAGAGCGAGGTACGGCACGCCAACGCTTACGCCCACCTCCTGGAGCTTTTGGGCCTGGAGGAGGCCTTTGGACAGGCCCTGGAGGGGGCGAGCGCCCTCCGGGACCGGGCCCAGGCCCTGGGAGAGGCCCTTCGGCGCGCCCAGGGGAAGGACCTGCGGGAATACGCCCTCGCCCTCTTCCTCTTCTCCGCCTTCACGGAACACGTCTCCCTCTTCTCCCAGTTCTACGTCCTCATGGCCCTAAACCGCCGCGGCAACCGCTACAAAGGGATCTCCAACGCCATCGAGGCCACCAGCAAGGAGGAGAACGTCCACGGCCTCTTTGGGGTGGAGCTCCTCCGTCTCCTCAGGACGGAGCACCCCGAGGCCCTGGGGGAGGAATTTCAGGAAGAGTCTCTACGCCTCGCCCAAAAGCTCTTCCGGGCCGAGGAAAACCTCCTGGGCTGGCTCTTCGCCATGGGGGAACCCTCTTTGGTGGGGCACGGAGAAACCCTGGAGTTCCTCAAGGGACGCTTCAACGAAGTCCTCGCCCTCCATGGACTCCCCGAAGCCTTCCCTGTGGACCGGGCGAGGCTTCGGGACACGGAGTGGTTCACCCTGGAGCTCCTCGCCGACAAGGAGGTGGACTTCTTCAACAAGCGGAGCGTGGCCTACGCGCGCAGGGTACAAAGCTTTGATCCGGAGGAGCTTTTCTGAAGGAGGAGGCATGACCAAGACCAAGCGGACCTACGAGCCCTGGTACTGGGCCAACGAGCACACCCGCCTCTACATGCGCCGGGGCTACCTGCTGCCCGGGGTGAGCGTGGAGGAGCGGGTGAGGGAGATCGCCCAGCGGGCCGAGGCCCTCACCAAGGTGGAGGGGTTTGGCCGCAAGTTCCAGGAGTACGTGGCCCGGGGCTGGTACTCCCTCGCCACCCCCATCTGGGCCAACTACGGCCTCAGGCGGGGCCTTCCCATCTCCTGCTACGGCACCTACGTGGAGGACGACACCGCTTCCATCCTGAGGGCGGTGGCCGAGGTGGGGATGATGAGCAAGCAGGGGGGAGGGACCTCCCTCTACCTGGGAAGGCTCCGCCCCCGGGGGGCCCCCATCCGGGACAACGGGGAGAGCAACGGCTCGTTTGCCTTCGCCTCCCTCTTTGACCGGGTGATCGAGGTCTTCAACCAGGGCTCCACCCGCAGGGGCCAGTGCGCCGCCTACCTGGACATAGAGCACCCTGACCTCGAGGAGTGGCTTTCCATCCAGCGGGAGCACTCCCCGGTTCAGTCCCTCTTCTGGGGGGTGAGCGTGGGGGACCGCTGGCTTGAGGAGATGATCGCCGGGGACGGGGAGAAGCGGGCCCGCTGGGCCAAGGTCCTGAAGAGCCGGGCCGAGGTGGGCATCCCCTACCTCTTCTTCCGGGACAACGCCAACCAAAAGGCCCCCGAGGTCTTCAAAACCCTCGGCAAGACCATCTGGGCCAGCAACCTCTGCACGGAGATCATGCTCCCCTCCTCGGAGGAGGAGAGCTTCGTCTGTTGCCTCTCCTCCCTGAACCTCCTCCACTACGAGGAGTGGAAGGACACGGACGCGGTGGAGACCCTGGTCATTTTCCTGGACTCCGTGCTGGACGACTTCATTGAGAAGGCGGAGGGCATCCCCTATATGGAACGGGCGGTGCGCTTCGCCAAGCGCTACCGGGCCATCGGCCTCGGGGTCCTGGGCTGGCACAGCTACCTCCAGTCCCAAAGAATCCCCCTGGAAAGCCCCGAGGCCTTCCGGAGGAACGCCGAGATCTTCAAGACCATACGGGAGCGGGCCGAGGAGGCCTCGAGGTGGCTGAGGAAGCGGCACCCCGAGGACGAGCTCGCCGGGGTGGGGGAGCTTAAGGAAAGGCGCAACGCCACCCTCCTCGCCATCGCTCCCACCAAGTCCAGCGCCTTCATCCTGGGCCAGGTCTCCCCCTCCATAGAGCCCTACACCAGCAACTACTACCTGAAGGACCTACAGAAAGCTCGCGTCCCCTTCAAGAACCCCTTCCTGGAGGAGGTGCTGAGGGAAAAGGGCAAGGACGAGGAAAAGGTCTGGCGGAGCATCCTGGAGCACAACGGTTCCGTGCAGCACCTGGACTTCCTCACCGATGAGGAAAAGGCGGTGTTCAAGACCTTCGCCGAAGTCTCGCAGATGACCCTGGTGAACCTGGCGGCCTCGAGGCAGAAGCACATTGACCAGGGGCAGTCCCTGAACCTTGTGATCCACCCGGAGGCCCCGCCCAAGGACGTGAACGCCCTGGTCCTCCACGCTTGGCGCTCGGGCCTCAAGGCCCTCTATTACCAGTTCAGCCAGAGCGTGGCCCAGGCCTACAGCCGGGACCTCCTCCTCTCCTGCCAAGCCTGCGAGAGCTGA

Protein sequences of DBSCAN-SWA_1

>NC_017273|13556:23423|13556_16145_-|WP_014510997.1|tRNA|DBSCAN-SWA
MDLPKTYDPQSVEPKWAEKWAKNPFVANPKSGKPPFVIFMPPPNVTGSLHMGHALDNSLQDALIRYKRMRGFEAVWLPGTDHAGIATQVVVERLLLKEGKTRHDLGREAFLKRVWEWKEASGGTILQQLKRLGASADWSREAFTMDEKRSKAVRYAFSRYYHEGLAYRAPRLVNWCPRCETTLSDLEVETEPTPGKLYTLRYEVEGGGFIEIATVRPETVFADQAIAVHPEDERYRHLIGKRARIPLTEIWIPILADPAVEKEFGTGALKVTPAHDPLDYEIGERHGLEPVSVINLEGKMEGERVPEALRGLDRFEARRKAVELFREAGHLVKEEDYTIALATCSRCGTPIEYAIFPQWWLSMKPLAEKVIRGLERGDIAFVPERWKKVNLDWLRNVKDWNISRQLWWGHQIPAWYCEDCGAINVPRPERYLEDPTHCEACGSPRLRRDEDVFDTWFSSALWPLSTLGWPEETEDLKAFYPGDVLVTGYDILFLWVSRMEVSGYHFMGERPFKTVLLHGLFLDEKGQKMSKSKGNTIDPLELVARYGADALRFALLYLATGGQDIRLDPRWLEMARNFANKLYNAARFVLLSREGFQAKEDAPTLADRFMRSRLSRGVEEITALYEALDLAQAAREVYELVWSEFCDWYLEAAKPALKAGNAHTLRTLEEALATLLKLLHPMMPFITSELFQALTGKEELALEAWPEPGERDEEAERAFEALKQAVTAVRALKAEAGLPPGQEVRVFLEGETAPVRENLEAFRFLARAELLPERPEKALVKAMPKVTVRMPLEGLLDVEEWKKRQEKRLKELLSLAERSQRKLAAPSFREKAPKEVVAAEEARLKENLEQAERIREALSQIG
>NC_017273|13556:23423|21743_23423_+|WP_014511005.1|DBSCAN-SWA
MTKTKRTYEPWYWANEHTRLYMRRGYLLPGVSVEERVREIAQRAEALTKVEGFGRKFQEYVARGWYSLATPIWANYGLRRGLPISCYGTYVEDDTASILRAVAEVGMMSKQGGGTSLYLGRLRPRGAPIRDNGESNGSFAFASLFDRVIEVFNQGSTRRGQCAAYLDIEHPDLEEWLSIQREHSPVQSLFWGVSVGDRWLEEMIAGDGEKRARWAKVLKSRAEVGIPYLFFRDNANQKAPEVFKTLGKTIWASNLCTEIMLPSSEEESFVCCLSSLNLLHYEEWKDTDAVETLVIFLDSVLDDFIEKAEGIPYMERAVRFAKRYRAIGLGVLGWHSYLQSQRIPLESPEAFRRNAEIFKTIRERAEEASRWLRKRHPEDELAGVGELKERRNATLLAIAPTKSSAFILGQVSPSIEPYTSNYYLKDLQKARVPFKNPFLEEVLREKGKDEEKVWRSILEHNGSVQHLDFLTDEEKAVFKTFAEVSQMTLVNLAASRQKHIDQGQSLNLVIHPEAPPKDVNALVLHAWRSGLKALYYQFSQSVAQAYSRDLLLSCQACES
>NC_017273|13556:23423|20758_21733_+|WP_014511004.1|DBSCAN-SWA
MPLTAPRLAYRPYEYPELLRFRDAIRHSYWVHTEFSFQSDLQDHALADEKERSLVERALLAIAQVELAVKLFWARVYDRFPKPEIAEVGLTFAESEVRHANAYAHLLELLGLEEAFGQALEGASALRDRAQALGEALRRAQGKDLREYALALFLFSAFTEHVSLFSQFYVLMALNRRGNRYKGISNAIEATSKEENVHGLFGVELLRLLRTEHPEALGEEFQEESLRLAQKLFRAEENLLGWLFAMGEPSLVGHGETLEFLKGRFNEVLALHGLPEAFPVDRARLRDTEWFTLELLADKEVDFFNKRSVAYARRVQSFDPEELF
>NC_017273|13556:23423|16619_17579_+|WP_029765920.1|transposase|DBSCAN-SWA
MKRMTLGERIGLAREALAQGLAPLPIVLRALEIPRATWYYYQKQKVAADRKREEEDLRLKRAMKKVLLEHPEYGYRRVTEALKRKGIPVNHKRVHRLLQDFHLSLKRTARRPKPNPLLQIVLLAGDKADLRASLLREREPEPFALLYTDFTLLPYRGGKAWFVPILDHRTRMVVAFGLGPSPSAELALEAWAEAKAFLRTRVGGLPRVLVHHDQGGPFLSHDWVGTLLREGQRLSYSLMGAKGNPVVESFFARFKAEGGDQFLEAKSLGELRGVVEERLRYYHESRLHSGLGYRTPREVMEEALGKTWEASHGRQGEGV
>NC_017273|13556:23423|18968_19895_+|WP_014511002.1|DBSCAN-SWA
MRLLVQNVHKRFGKLEALKGVSLELGAGEILGLLGPNGAGKTTLIKVVLGLLLPDGGEVVLEEDGARRRPQGHEFGVLLEGSRNLYVNLSLLVNALYFGGIRGLPPKEVRPRFEAWLERFGLKDRLHAPLASLSRGMQQKAALALALALKPRFLLLDEPTLGLDPVSRREFEGILLELKKEGWGILLTSHDLEVVERVSDRVAFLHRGEVRRQGPTRALLRDWAGEGYRVRLAEPKAEALLQALGPGWSAEGPEVLFFLGPWEALREVLGRLPVEVLEVSRGTPSLEALFLHLFGEARPSPGAQPRTV
>NC_017273|13556:23423|18201_18969_+|WP_014511001.1|DBSCAN-SWA
MAYLRQFFAEIWLNLNFYRIYWPDFLAGLFADMAFFYAIWMALGSVVVSNPSADLGGGQNILFMYAVFGIVVGIFQSVAFTVAQEAQRGTLEHLALARGGLVVQLLFRGASDSLFILFRTGVLLGVLLVLTGASFNPKPFWLLALALLVVSALGFSLSMAALALYFKKILSFFTIIQFSLLLYFFSVNHWRDYMVYLPLAPAAHLLSRSFSGGGEWTEWVVLSAFLQALLFVCFGLLALGYTHRLVRLRGILGRY
>NC_017273|13556:23423|20376_20778_+|WP_014511003.1|DBSCAN-SWA
MRETRMVYPVFPGETNHYGTLFGGTVLAWMDQAAFVAATRHARKKVVTVHADAVDFKRPVPLGAIVELVARVREVGRTSMRVEVEMWVEPVKEGEEAYLAARGGFVLVAVDERGRPSPVPPLEGGEARAPHGA
>NC_017273|13556:23423|17565_18015_+|WP_014511000.1|transposase|DBSCAN-SWA
MKVSKFRGPDQLAHVPQSEREAVAEELKEVFTVKRRSTAESLAQGFMERYRERYRRAVEVFAQGIEEALTYLEFPGSHQGQIKSTNVLERLFREVKRRTKVVGVFPSEKSLANLATVVMLRASEDWAFRRYMDMGPLWAAEEKPTKKAT
>NC_017273|13556:23423|16321_16603_+|WP_014510998.1|transposase|DBSCAN-SWA
MKKPKAVPPQVKFQAALEAIKGEKSLVELARIYNVHPNTILKWKAELMEKGATVFSNETQEKELEKRIRDLEQLIGKKEVEIALLKKPNLRFA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014510997.1|13556_16145_-|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	3.1e-144	38.4
WP_014510998.1|16321_16603_+|transposase	transposase	NA	NA	NA	NA
WP_029765920.1|16619_17579_+|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.0e-12	28.1
WP_014511000.1|17565_18015_+|transposase	transposase	A0A220NQR7	Corynebacterium_phage	3.7e-05	42.2
WP_014511001.1|18201_18969_+	hypothetical protein	NA	NA	NA	NA
WP_014511002.1|18968_19895_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.4e-24	33.5
WP_014511003.1|20376_20778_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_014511004.1|20758_21733_+	ribonucleotide-diphosphate reductase subunit beta	M4I0Q2	Staphylococcus_phage	7.4e-75	45.2
WP_014511005.1|21743_23423_+	ribonucleoside-diphosphate reductase subunit alpha	Q2XUY0	environmental_halophage	5.2e-177	54.4

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017273|89674:150987|DBSCAN-SWA
GGTGAAGGCCAAGCCTAAAGCCGCGCGCAAGCGTACCTCGCAGAAGAGGGCGAAAGCCTTCACCGGAGTCCACGCCCTCCTCCTCTTCCCTTCCGGAGAAGACCACAAGGCCACCCTGGACCTCATGCGCCGCTTCTCCGCTGGGGTGCGCTACGCCTACAACCGCTTGCTTGAGGGTCAGACCAGGGAAGCCCTCAAGCGGGAAAATGGCCCCCTCCGCACCTTCTTCCGCCTCAACACCCGCTACGCCGACGACGCGGTGATGAAGGCCCAGGCCGTCCTGGACTCCGCCCGGGAGAGAGGAGAAGACCCTAGGAAGGTCGTCTTCGGGGGAAGGAAGCTCTTTGAGACCCTGAGGCGCAGGCACCTCTCGGGTAAGCCCCTGAAGGAGGTCAAGCGGGAGTGGAAGGAGAAGCGCCAGGGTCTCCTCTACTCCCGGGGGGACAGGACCAAGGGGGGCAACCTCAACCTCCGCCTGGAGGCCGAGGACGGGGCTTTATGGCTCCGCGTCAACCTGGGGAACGGGAGGTACGCCTGGGCCCTGGTGAAGACCTCCCACCCGAACCTGAGCGCCCTGGTGGAGCGTGTCCACGCCTCCCTCCCCTACAACGTGGAGCTCTCCCTCAAGGACGGGAAGGTCCACGCCACCTTCACCTGGGAGGAAGAACCCACACCCCTCGCGGCCACGAAGGAGAACGGCGTCCTGGGCATAGACGTCAACTCGGACCCCTACCACCTCGCCTTGGCGGTGGTGGGGCCGGATGGAAACCTGAAGCGCCACCTCACCCTCTCCCTGGAGGAGGTGGACCGCGCTCCGAACAGGGGGACGAAGGAGCTTCTCCTGTGGAAGATCGCCCACCAGGTGGTCTCCCTAGCGGAGGAGCACGGCGTAGCCGTCGCCACGGAGCGCCTGAAGCACCTCCCCAAGGGAAGGAGAGGGGACGGCTCTGGAAGAGCTTTCCGCAGGAAGCAACACCGCTTCGCCTACGCCTCCCTCCTCCGGAAGGTCCATTCGTTGGCGAGGAAGAAAGGTGTCCAAGTCGTGGAGGTGAACCCCCAGGACACCTCCGCCATCGGGATGCTCAAGTACGCTCCCCAGCTTTCCCTGTCCAAGGACGTGGCCGCCGCTTACGTCATCGGGAGAAGGGCCTTGGGGTTCAAGGAGAAGCTTCCCAAAGGCTACGGGAAGCTTCTCCGGGACGAACGCTTCAGGGACCACGCCCAGGGCTTCTATGCCTCCAGAGTCCGGGAACTCCAAGCCAAGAAAGCGCAGGAACAAAACCCCTACCTCAGGCGCAGGCTTTCCCGGGAGATCGGGAAGGCGAAGCGCCACCTCTCCTTGCTTTCAAGCCTTCAGGGCTCGCCGGGGAGCCAAGAGGGGTCCACCGAGGGAAGGAACCTTCTTGGCGGCAATCCCTGGAGGGTCCTGAGGGTAGGCCTCTTCCTTCCCCTCCTCGGGCGCGAGGTGCCGAGGGACCTCTCCCCGCTGAAGGTCATCCTTCACCGGGGAGCGTGGGAGGGGTGGAAGGGAGGCTTAGGTCCTCCTCCTGGTGGAGGGCCGAAGTGCGCTAATGTGCACTTTGGTTGACCAGGCCCGCAGGCTCTGGCTGGAGACCGCTTACGAACACAGGGACGAGATTCCCCTTCCCTCCAAAAGGCCCTAGCGTGGCGGTTCCAGGGCCACGGGGTGGGAGCTGGCGTAAACGACCCCGCCTTGTGTTAGCCTTGACTAACCTCAAGAGGTCTACTAACATGGAGGTGTGCGGTGGCGCAGTACCGGGTGGAGCTCTATCGGGACGCCCGAGGGTACTCTCAAGTCCTGGAGTTCTTCAACACGCTCAAGAGGAGCAACCCCAAGCTTCTGGCCTTCGCCCAGCGTCTCCTCAAGAACTTGGAGGAGCACGGCCCTGACTTGCGTCCACCTTTGGCCAAGCCTCTTAAAGGGCTCCAGGCGCCCATCTGGGAGCTGCGCCATCCTTCCGGGCTTCGGCTTTACTACTGGCGGCAAGGGGCCACGCTCTTCGTCGTCGCCGCGGGAGAGGTTAAGAAACGGGACGAGGCCGACCCTGACTTGCTGGAGTTCGCGGTGAAGGCGTACAGGGAAAGCCAGAGAAACGTTAACTAGGGGGGACTTGTCATGGGAAACAACATCAACTTTAGCGACTACTTCCGGGAGTCCATGAAGGACCCGGAGGCCCGGCGGCTTTACCGGGAGGTCCTGGACGAGGAGCTCTCCTGGCTTCTCAGCTACCTGAGGGAGGAGAGGAGGCTTTCCCAGAAGGAGGTGGCCGAGCGCCTCGGGGTCTCCCGGGGCCGGGTGAGCCAGCTGGAGACCTCCGCGGGCCTCTCCATGAGCCTGGAGAGCCTGGCCCGCTACGCCCAGGCCCTGGGGCTTTCCCTGAGGCTGGAGTTCGCCGACGAGAGGGGAGAGGTCCTGGCCCGCTTCTCCCTCGCGGCGGACGAGCCCGTGGCGGAGACGACGAATCCCGCTTGGGAAAACGCCGGGGCCGGCTGGGAGCCTGCTTCCGGCAAGGCCTCCTGGGCTTCTTGGGCCGCCTAGAGCATGGAAAGCAAGTCGGAAACCATCCGCAGGCTTTACCGGGAAGGGAAGAGCGTCTCCGAGATCGCCAAGTCCCTGGGGCTGAGCTACCAGAGGGTCTACAACACCCTGAAGCGCTCGGGCTTCCTCAAGCCCAAGGGACGGGGGCCCTCGCCTTCGGGGGAGCCCGATCCCGAGGCCTACGCCAGGTTCCTCCAGGGTCTGGAGATCCGGTCCATGGAACTAATGGAGGTCCACGCGAAGCTGGAGCGTTCCCCCAAGGGGAAGCTCTCCTTCCGCATGGGCCTCGAGGCCTTCGGCCCCGAGCCGAGGGAGGGGGGCTTCTCCGCCGGGCTCGCCTTGAGCCTGGACTTCCAGGACGAGGAGGGGCCCTTCGGTTTCCTGCGGCTCAGGGTGAGGGCCGGCTACGCCACGCCCCTCTTCCCGGACGAGCCCCTCTTCCGCACCTTTAGGGAGCGAAACCTGATCGTGCACCTCTGGCCCTACCTGAGGCTTTACGTGGACTTCCTGACGGCGCAGATGGGGCTTCCCCGCCTGGTCCTGCCCGCCTGGAAGGTCTAGGAGGGGTCGCCTGCCGCCCCCTTGGGCCGTTTGGGGGCTTAAGCTTTGAGGTATGGCGCTTAGCAACCGGGAGATCGTGGGTAAGGGCCTGGACCTCCTTCGGTCCGGGCTGAGGCCTTTCGTGGAGCGGGAGTACCGACGGGTCTACGGCGAGGAATGGGTCAGGGAGGCGGGGGAGGTGCTTAAGGGGGACCGGGCTTCCCTGCAAGACCCCGACGCCCAGGCCCTCCTCAAGCTCATGGACTACCGCTGGAACGAGGTTTTTGACGAGAAGCTCGGGCGCTGGGGCAGGACCCTGGTGAAGGAGCTTCTGGAGTTCCGCAACCGCTGGGCCCACCAAGGCGCCTTCTCCTTTGAGGACGCCCACCGGGCCCTGGACAGCATGACCCGCCTCCTGGAGATGATCGCCGCCGAGGAGGCCCAGGAGACGGTCCGCATGGCCCGGGAGCTCCTCAGGCGCCGCTTTGAGGAGGAGGCGAAGCGGGAGGCGGAGCGGGCGGTCAAGCAGTCCCTGGCCGTCGTCCCCCAGGGCCTCAAGCCCTGGCGGGAGGTGGTCACGCCCCACCCCGACGTGGCCTCGGGGCGGTACAGCGAGGCGGAGTTCGCCGCCGACCTGGCCCAGGTACACCGGGGTGAGGCCGGGGAAGAGTACGGGAACCCCTTGGAGTTCTACCGCCGCACCCACCTCACCTCCGGGCTGAAGCGCCTCCTCCTCAACGCCCTGAAGCGCCTGGCGGGGGAGGGGGGGGACCCGGTGGTGGAGCTCCAGACGGCCTTTGGCGGGGGGAAGACCCACTCCATGCTTGCCCTCTACCACCTCTTCGGCGGGGCGGTGGACCCCGGGGAGGTGCCGGGCCTCGAGGACCTCCTGGCCCAGGCAGGGGTGGCCCGGGTGCCCTTGGCCCGCCGGGCGGTCTTCGTGGGCACCGCCTTTAGCCCCGCCCGTCCCCACCCCAAGCCCGAGGGGGTGGTGGTGCGCACCCTCTGGGGGGAGATCGCCTACCAGCTCGGGGGCGTGGAGGGCTACCGGATGCTGGAGGAGGAGGACCGCACGGGGGTGGCCCCGGGTTCCGACGTCCTCAAGGAGCTCTTTGACCGCTTCAGCCCGGCCCTGGTGCTCATAGACGAGTGGGTGGCCTTCCTGCGCAACCTCTACGGGGAGGAGGGCCTCCCCGCCGGGACCTTTGACCAGAACCTGACCTTCGCCCAGGCCTTGACCGAGGCGGCCAAGCGCAGCCCCCGCGCCCTGGTGGTGGCCTCCCTTCCTGCCTCCGACGCCGAGGTGGGGGGAGGAGGGGGGAGGGAGGCCCTCCTCCGGTTGCAGAACGTCTTCGGGAGGCTGGAGTCGGTGTGGCAGCCCGCTACCCAGGACGAAACCTACGAGATCGTGCGCCGCAGGCTCTTCCAGCCCCTTTCGGCGGAGGGCTACCGGGTGCGGGACGCCGTGGTGCGGGAGTACGTGCGCTACTACCGGGAGCACCGGGGGGAGTTCCCGAGCGAGGTCCTCGAGCCCCGCTACGAGGAGCGGATGCGCCTCGCCTACCCCATCCATCCGGAGCTCTTTGACCGGCTCTACGAGGACTGGGCCACCCTCGAGGGCTTCCAGCGCACCCGGGGGGTGCTCCGCCTCCTGGCCTCGGTGGTCTACACCCTCTGGGTCCGGGGGGACACCTCCCCCCTGATCCTGCCGGGGGGCCTTCCCCTGGACGCCGACGGCCCCCGCTACGAGCTCGTTCGCCACCTCTCCCGCCACCAGGAGGGGTTTGACCAGGTGATTGATTCAGACATAGACGGCCCCAACGCCAAGGCCTTCGCCCTGGAAAAGGAGCGCCCTTCCCTTGGCCGCCACCAGGCGGCCCGCCGGGCGGCCCGGGCGGTCTTTCTGGCCACCGCCCCCGCCGGGGCCGCCCCTACGGGCAAGCCCAGGGGGGTGGAGGGGGTCCGGGTCAAGCTGGGGGTGGCCCACCCCGGGGAGAGCCCGGCCCTCTTCACCGAGGCCCTGAAGGCCCTCTCCGAGCGCCTGGTCTACTTTCACGCCGAGGGGGACCGCTACTGGTTTGAGACCCGCCCGAGCCTCAACCGGATGGCCCAGGACCGGGCGGCGGCCGTATCGCGGGAGGAGGCCCTAATGGAACTGGAGGAGCGCCTGCGGGCCTGGGCCAAGGGGCGCCCCGCCCTCTTCCAGGGGGTGCACGCGGCCCCCGCGGGCTCGGGAGAGGTGGCGGACGAGCCCAGCCTGCGCCTTGTGGTCCTCTCTCCCCGGACCCCCTACGCCAAGGGGGGTTCGGAGGCGGAGCGGTGGGCCCGGGAGGTCCTGGAGGGGCGGGGCCGGGCCCCAAGGCGTTACCGCAACACCCTCCTCTTCCTCGCTCCCGAGGCCGTCCTGGTCCCCGACCTCGAGGAGGCGGCCCGCCAGTACCTGGCCTGGCGTTCCATTTGGGAAGACCGGGAGAGCCTGAACCTGGGGGCGGCGGACGTGCGCCAGGTGGAGAGCCGCCTTCGCCAGGCGGAGGACACCCTGAGGCTCCGCCTCGAGGAGGCCTACCGCCACCTCCTCGTCTTCCACCAGCCCGACCCCAAGGCTCCGGACCTGGAGGTGGACGCCCTCCGCCTCCTGGGGAGCGGCAACCCCTTGGAGCGGGCGGCCAGCAAGGCCCAGAACGAGGGGCTCGTCCTCGTGCGGTGGCACCCGGAGTTTCTGGGGGAGACCCTCGCCCGCTACGGGTTCTGGGAAGTGGCCGAGCCGGAAGGCGTCCTCCCCCTGAGGCGGCTTTGGGAAGACCTCGCCTCGTACCTCTACCTCCCCCGGTTGAAGGACGAAGGGGTGCTGCTCGCCACCGTGGCCCAGGGGGTTAAGGAGGGGCGGTTTGGTTACGCCGAGAGGCTGGAGGGCGGGGTTCCCAAGGGGGTGGTCCTCGGAGAGGAGGTGGCCCCCTCCCTGGGGGGTTACCTCCTGAAGCCCGAGGTGGCCGCCCGGTTTTTGAAGGAGAAAACCGGGGAAGACGTTCCCCCACCCCCGGACGGGGAGGGGGATGACGAGAAGGTCCCGGTCCCGCCTCCGCCTAGGCCTTCGAGGCCCCGCCGTTTCTACCTCAAGAAGACCCTGCGGATGGAAAGCCTCCTTCCCGAGGTGAGGGCCCTGGCCGAGGAGGTTCTCCTGCACCTTTACAAGGAGGGCGGTGTCCGGCTCGAGGTGGTCCTCGAGGCCCACGCCGAGGCCCCGGAGGGCTTCCCCGAAGACCTGGAGCGGGTCCTCAGGGAGAACAGCCGGGTGCTCGGGGCCGAGGCCTTCTTTGAGGAAGACTGAAGGCTGCCCATGGGCCTTCGGCCTAGAGAAGCTCCGGTGAGGACGCGCTGGGGTCTGGGGGTCTGTCCCCTCGTTTGACCCGTGTGGCCGGGATCCTCTCCAAGGGTGAGGTGGACAGCCGTGGGCTTTGGGAGGGTAGCATGGAGATTGCCCGGGCCCCTCGGCCGCGTTGCAGGTTTTTGTTGCTCAAAGTAGTCAAAAAAGCCTCTAAAACTTAAGCTCCAAGATCCGCGAGGCCCGGGCCCTTTTTTCTTTCCTTCAGTCATTGGAGGGCCTCGAGCCGGGCCCTGGCGGCCTGCCGTGGCTTTTTGGGTGGGGTGGTGGAGAGGGTCTGCTCGGGCCTCCGCGCGTCGGGGTCTCCTTTTTAAGCAAGAAAAAGAAGATTGACAAGACTTAGGCCCCGAGGTATGCTGTCCTCCGTGAGGAGGACAACAGTGCGCCCATTGCTGTCCCAGATGGCCCTCGAGGTCCAGGTTCCCCTGCGGGTGGCTAACCCCAGCGGTCTGGTCCGGTCCCCGGCCTTCTCGGTGGACGGGGGCCCCTTCGCCCCCCTCCGCCAGACCCGGTATATAAGGGGCGAGCCGGTGGAGACCGTCCTATTGGACTCCGTGGAGAGCCAGGCCAACCGCCAGGAGGCGCTCCTTTACCGCCACCTCCCTCTGCCCGACGTTCAGGTGGAGCTTTTTGATGGACGCCGCGTCTCCCAGTACGAGGCTCCGGGCCGCATCCTGGACGCCATTTTCCGGGAGGCCACCCTCGGCGGACAGCCCTCCCATCAGACTCCCCTCTTTCAGGCCATCGCCCGGGGAGGGGAGGAGGCGGAACGGGCCCTCTTCCGCCACTCCCCCCTCACCCTGGTCTACGGGGGCTGGCTCTCCTACGGGGACATTTCCCCAGAGGTGGCCCCCAAGTGGCCCAGGCTGGTGGCCCTGGAGATCCTGGGCCTGGAGCCTCGGGAGGCTCACCGCACGAGCTCCAGGTTGGACCCTCTCGGCGTCCCGGGGGAGCTTCCCCTGCCCGAGGCCATGTCCCAGGCCCTGAAGGAGCAAGGAAAGAAGGGTAGGCTTTCCGAGGCGGGCCTGGGCCGCATCCCTCCCACGGCGAGCCCCATGGACGTGGCGGTCAGGGGGGCGGTCCTGGTGGGGGCGGTCTCCCTGGTGGGCTTGAGGAACCTGCGCCTGCCCCAGGAGGCCAAGGAGGTTCTCCTCGCCCTCGCCCTCCTGGGGCTTGCCCTGCAGCACAAGGAGGGGTACAGGCTGCGCTCGGGGGCCGACCTGGTGCCCGAGGAAGGGGGTTGCCTTCGGGTCCGGGCCCTCCCTTCCGGGGAGGAGGTGTGCCTGGAGGTGGAGCCCCTGAGGGAGGAGCTGGACCGGCTCCTGGGGGAGCTCCCCGAGGAGTTGCGCTGGCCCGGGGAGCCGGTCGTCCTGCAGGCCAACGAGACCCTGAACCAGCTCTACAGAAACGCCCTCTTGGGCAAGGCCGAGAGGGCCAAGGCCAAGCGGGAGAAGGAGGGGTAGTGTACCTGGCCTTCTTCGTCCGGTACGCCGTGGACGCCCACCGGGGCAAGGGCCCCCGGGGCCGGGAGTTCCCTCCCCACGAGGTGCGCCTGCGGGGGGGGCTGGTGCGGTCCTGGGCCCTGGAAGGGAAGCCCGAGGAGGCCACGAAGGCCCTGGAGTGGCTGGAGACCCTGCCTCCGCCCGGGGTCCTGGCCCCCAGGGTCCTGGAAGGGAACTGGCGCACCCGGGTGGCCTACGTTCCTCCCCACGATCTGCCCCAGCCGCCCGGCCACAGGGAAAAGGTGCCCCTCCTGCACCATGTCCTTCCCCTCTCCGGAAGACTCCTCGCCTACGCCTACCCCCTCGAGGGCCGGGAGGAGGAGGCCGAGGCCCAGCTCCCCACCCTGGGACGCTTGGCGGGCAGGATCAGCTACCTGGGCACGAGCCGCAACCTGGTGTGGGTGGAGGCCCGGCTGGTGGAAGACCCCCTCGGGGCCTACCGGGAGGAGGCCGGCCAGGAGCCCTGGCTCCTGGTGCCTGCCGAGGCGGGGGACCTCTGGATGCGGGTCGCTCCCCCGGGCTTCCTCCGCCTGGCCGAGGAGCGGTTCCAGGCCCGGGTGCGGGAGCTTCCCCACCGCTGGGTGCCCTACCGGGAGCCTGAGGCCCTGCGGAGCTCCCAGTCCCTCTCCCCCTGGGGGGCCTGGCGGGTCTTGGCCCTGGACCCTCCCTTGCCCCTGGAGTGGGCCCCCCTCTTCGCCCACGCCGCCCGGAGGGCCCTCCTGAGCCTCCTGCCCCCGGGGGCGCCCCCAGAGCTCACCGGGCACGGGGCGGGAGGCGGTCCCCTAAGGGCCCCCCACCTGGCCCTGGTTCCCCTCCCCAACGTGGGCCACCGCTACGGGGACGGCCGCGTCCTGGGCCTGGCCTTCCTCCTGCCCCGGGAAGCGGGCGGGGCCGTGGAGCTCGCCCTCCTCGAGGCCCTCCTCAGGCTGGAGGAGGTCCGCCTGGACGGCCTGGCGGTGCGCCTCCTTCCCCCCGACGGGCGCTGGGCCCTTCGGGAGGGGCGCTGGCGGCGCCCCGCCCGCCGTTTCGCCAGCGTCACCCCCGTGGTCTTTGACCGTTACCCCAAGCGGGGGGACGTCCTCGCGGCCCTCCGCTTCTCCGCCCGGGCCGCGGGCTTCCCGGAGCCCGAGGAGGCCTGGGTCTTGCCCTACCCCCGGCCCCAGGGGGTGCCCCTAAGCCGGGACTTCCGCCTGCCCCCGGGGGTGGAAGGCTACGTGGCCCACGCGGAGGTCCTCTTCCCCGAGCCGGTTTCCGGCCCCGTTCTCCTGGGACGGGGGCGCTATTTGGGCCTTGGGCTTTTCGTCCCCTTGGAGGTGGAGGATGGAGGCGCTTGAGCGGGCCTTCGCCGAAAACCCCCTTACCCTGGAGGACTTCCCCGGCTTCTTCCTCGAGGCCACGGGGCACGAGCCCTACCCCTGGCAGGAGGCCCTCCTGCGCCGGGTGGTCCGGGAAGGGTGGCCTGAGGCGGTGGCCGTGCCCACCGGGGCGGGGAAGACCATGGTCCTGGCGGTGGCCCTGTTCCTCATGGCCCTGGACCCCAAGGCCCACCGCCGGGTGGTCTACGTGGTGAACCGCCGCCTGGTGGTGGACCAGGCCCACGAGGTGGCCCTGGGGCTCAAGGAGAGGCTGGAGGAGGCCCTGGCGCGGCCCTCCGGGGAGGCCACCCCCCTGGTCCGGGCGGCCCGCAGGCTGGCCGCCCTTGGAGGCGGCAAACCCCTGGAGGTGGTCCGGCTTCGGGGCGGGGTGCCCCGGCCCAGGCCCACCCTGCAGGACCCCGCCCGGCCCGCGGTGGTCCTGGCCACGGTGGACATGGCGGGAAGCCGGCTCCTCTTCCGCGGCTACGGGGTCCCCCGGGGGCTCCTCCCCGTGGAGGGGGCCCTCTTCGGGACGGACGCCCTCTACCTCCTGGACGAGGCCCACCTGGAGGCGCCCTTCCTCGCCACCCTGGAGGCCGTGGCGGGGTTGCCTGGCCCCTGGGGCCGCCCGGGGGTGCGGGCCGTGGCCCTCACCGCCACC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GGACGACCGCCGCTACGGCCCCCTGGTGGCCGCCGTGGGGTTTGACCAGGGCCTGCCCGTGCGCCTCCTCTACCGCGTGCCCGTGGGGGAGAGCCGGGTGGGAAGCCTCGCCGCCCTCCTGGCCCAGGCCCTCCAGGACTTCCCCTACGAGGCCACCCTGCGCCTCCTCTTCCACCCCCTCTTTCCCTGGGAGCGAAAGGTGGACCTGGACCAGGCCCGCCTGCGGAGGCCTTCCGGGGAGGCGTGGAAGGGGCTCGGCCTTCCCGGGGAGCTTCTGGAGCTCGCCCAGGGAAAGACGGGCGGGGAGCTCGTCCAGGGCCTCCGCCGGGCGCTTTCCCCCCTGAGGAAGCGGCTTGAGGGCTGGCCCCGGGAGCGGGCGGCCCTCGAGGCCCTCCTGGAAGGCCTCGGGGAGCTGGAGGAGGAGGACCGGGAGGGCTTCTTCCAGGGGATTTCCGAGCTCCTCTACCACCTCACCGTGCCCGCCCAGCCGGGGTACGGGGGGGTGGAGCTCCACACTCCCCTGGCCCGCTACGGAGGGGCCTTCCGCCACCTCTTCGTCCTGGGCATGGCGGAAGGCCTTACCCCGGTCCCGGTGGCCGAGGACCCCTTCCTGGGCCTGTCCGAGGTGGAGGAGCTGGAGCGGTTCGGGCTCTTTCCGGAGAAGCCCTGGGAGGCCGCCGCCCGGGAGGCCCTGGTCTTCGCCGCCCTTCTAGGGAGCTTGAAGGAGGACGGCGAAGCGGTCCTCACCTACCCGGAGGTGGTGGAGGGGAGGCCCGTCCCCATGAGCCCCTTCCTGGAGCGCCTGGGCCTGGAGCCCCGAAGCCCCGGGCGCACCCTGGTGGGAAGCCTGGTGGAGGCCCGCAGGCTTGGCCTGTGGGAGGGAGACCCCCTCCAGGAGGCCATGGAGCGGGCCCTCGAGGCCGAGAGGGCCCGCCTGGAAGGGGAGGCCTCCTCCCCCCACCACGGGGCCACGGGGAGGCCCTTCCTTCCCGCAAGCCTCAGCGTCTCCCAGCTTGAGGACCTGGCCACCTGCCCCTTTCGCTTCTACGCCAAGCACCTCCTCCGTCCCCGGGGGGACCGGGAGGCGGGGGACGGGGACCGGGAGGACCTGGGAACCTTCGTCCACCAGGTCCTCGCCCGCGTCTTCCGGGCCGCGCTGGAGAAGGACGCACGGAGGGGCGAGGAGGTGAGGGCCCTTGCGGCGGGGGGCCTTCTGGGGGAGGCCTTCTCGCGGGTGGAGGAGGAGTGGAAGGGGAGGCCCAATTCCCCCTTCTTCCTGAGGCGGCCCGACTGGCCTCACCGCCGGAGGTGGGTTCTGGGGCTTCTCGCCCGGGCCTTTGAGGACGACAAGCAGTTCCTGAGGGGGGACGTGAAGATCGTGGGCGTGGAGGTGGAAGCGAAGTTGGGAAGGGGGTTTAGGGGGATGGTGCCTGGCTACGAGGGCCTGGAGGTTCGGGGAATCATAGACCGCGTGGAGGAGCGCTCGGGAAGCCGCTTCTACTTGGACTACAAGCTGGGGAGCACCTCCCCCCGGGTGAAGGACCCGAGGACCGGGAAGCTCTCGGCCGACCTGCAGCTTTCCCTCTACATCCTCCTCCACGGAGAGGGCAGGGGAGCGGGGGTCTACTACCTCCTCGCTTCCAGAGAGGCGAAAACGGTAAATCTGGACCGGGGCGCGCTCTGGGCAATCTTTAAGGAGATTCGCAGGACGTTGAAAAGCGGCGCCTTTGAGCCCAGGCCCGACGCGAAGGCCGAGGCCTGCCGGTCCTGCCCCGTGGAGCTCCTTTGCCGCTACGAGGGGAGGTGAGGGATGGAGGCGAATCTCTACGTGGCGGGGGCGGGGACGGGCAAGACCTACACGCTGGCGGAGCGCTACCTCGGCTTTTTGGAAGAAGGGCTGTCCCCCCTCCAGGTGGTGGCGGTGACCTTCACGGAAAGGGCCGCCCTGGAGCTGCGCCACCGGGTGCGGCAGATGGTGGGCGAACGCTCCCTCGGCCACAAGGAGCGGGTCCTGGCCGAGCTGGAGGCGGCCCCCATAGGCACCCTCCACGCCCTGGCCGCCCGGGTCTGCCGGGAGTTCCCCGAGGAGGCGGGGGTGCCCGCGGACTTCCAGGTGATGGAGGACCTCGAGGCCGCCCTCCTCCTGGAGGCGTGGCTGGAGGAAGCCCTCCTGGAGGCGCTCCAGGACCCGAGGTACGCCCCCCTGGTGGAGGCCGTGGGGTACGAGGGGCTTCTGGACACCCTGCGGGAGGTGGCGAAGGACCCCCTGGCCGCCCGGGAACTCCTGGAGAAGGGTCTTGGGGAAGTGGCGAAGGCGCTCCGCCTCGAGGCCTGGCGGGCCCTCAGGCGCCGGATGGAGGAGCTTTTCCACGGGGAGAGGCCGGAGGAGCGGTACCCGGGCTTCCCCAAAGGATGGCGGACCGAGGAGCCTGAAGTTGTTCCCGACCTCCTGGCCTGGGCCGGGGAGGTCAAGTTCAACAAGAAACCTTGGCTTGAGTATAAGGGCGACCCCGCCCTCGAGCGGCTCCTGAAGCTTCTAGGAGGGGTGAAGGAAGGGTTTTCCCCGGGGCCTGCGGACGAGCGCCTGGAGGAGGTCTGGCCCCTCCTCCGGGAGCTGGCGGAGGGGGTTCTGGCCCGCCTGGAGGAGCGCCGCTTCCGGGCCCGGCGCCTGGGCTACGCCGACCTGGAGGTGCACGCCCTCCGTGCCTTGGAGAGGGAAGAGGTGAGGGCCTACTACCGGGGGCGCTTCCGGCGGCTCCTGGTGGACGAGTTCCAGGACACCAACCCCGTACAGGTCCGGCTCCTGCAGGCCCTCTTCCCGGACCTCCGGGCCTGGACCGTGGTGGGGGACCCCAACCAGTCCATCTACAGCTTCCGCCGCGCGGACCCCAAGGTGATGGAGAGGTTCCAGGCAGAGGCCGCGAAGGAGGGTTTGCGCGTCCGGCGCCTGGAGAAGAGCCACCGCTACCACCAGGGCCTGGCGGACTTTCACAACCGCTTCTTTCCCCCCCTTCTCCCGGGGTACGGGGCCGTGAGCGCCGAGAGGAAACCCGAAGGGGAGGGCCCGTGGGTCTTCCACTTCCAGGGGGACCTGGAGGCCCAGGCCCGCTTCATCGCCCAGGAGGTGGGGCGCCTGCTTTCGGAAGGCTTCCAGGTCTACGACCTCGGGGAGAAGGCCTACCGGCCCATGAGCCTTCGGGACGTGGCGGTCCTGGGCCGCACCTGGAGGGATCTCGCCCGGGTGGCCGAGGCCCTTCGCCGCCTGGAGGTGCCGGCGGTGGAGGCCGGGGGCGGGAACCTCCTGGAGACCCGGGCCTTCAAGGACGCCTATCTGGCCCTGAGGTTTCTGGGAGACCCCAAGGACGAGGAGGCCCTGGTGGGGCTTCTGCGTTCTCCCTTCTTCGCCCTCACCGACGGGGAGGTCCGCCGCCTGGCGGAGGCGCGGGGGGAAGGGGAGACCTTATGGGAGGTTCTGGAACGGGAGGGGGACCTTTCCGCCGAGGCCGAAAGGGCCCGGGAGACGCTCCGGGGCCTCCTCCGGCGCAAGGCCCTCGAGGCCCCAAGCCGACTCCTTCAGCGCCTGGACGGGGCCACGGGCTACACGGGGGTGGCCGCCCGTCTCCCCCAGGGCCGGAGGCGGGTGAAGGACTGGGAGGGCACCCTTGACCTGGTGCGCAAGCTGGAGGTGGGGAGCGAGGACCCCTTCCTGGTGGCCCGCCACCTCCGCCTCCTCCTCCGTAGCGGGCTTTCCGTGGAGCGCCCCCCCTTGGAGGCGGGCGAGGCCGTGACCCTCCTCACCGTCCACGGGGCCAAGGGTTTGGAGTGGCCCGTGGTGTTCGTGCTGAACGTGGGGGGGTGGAACAGGCTAGGTTCTTGGAAAAACAACAAGACCAAGCCCCTCTTCCGCCCGGGCCTGGCCCTGGTGCCCCCTGTCCTGGACGAGGAGGGCAACCCCAGCGCCCTCTTCCACCTGGCGAAGCGCCGGGTAGAAGAGGAGGAGAAGCAGGAGGAGAACCGGCTCCTCTACGTGGCCGCCACCCGGGCCTCCGAACGGCTTTACCTCCTTCTCTCCCCCGATCTCTCCCCTGATAAGGGCGACCTGGACCCCCAGACCCTGATCGGGGCAGGGTCCCTGGAGAAGGGCCTCGAGGCCACCGAGCCGGAGAGGCCCTGGTCCGGGGAGGAGGGGGAGGTGGAGGTCCTCGAGGAGAGGATCCAGGGCCTTCCCCTGGAGGCCTTGCCCGTCTCCCTCCTCCCCCTGGCGGCCAGGGATCCCGAGGCGGCCCGGAGGCGCCTTTTGGGGGAGCCCGAACCAGAAGGCGGCGAGGCCTGGGAGCCGGACGGCCCCCAGGAAACCGAGGAAGAGGTCCCGGGCGGGGCCGGGGTGGGGCGGATGACCCACGCCCTCCTGGAGCGCTTTGAGGCCCCGGAGGACCTGGAGAGGGAGGGCCGGGCCTTCCTAGAGGAAAGCTTCCCCGGGGCGGAAGGGGAGGAGGTGGAGGAGGCCCTGAGGCTTGCCCGCACCTTCCTCACTGCCGAGGTCTTCGCCCCCTACCGTGGGAACGCCGTGGCGAAAGAGGTGCCTGTGGCTTTGGAACTCCTGGGGGTGCGCCTCGAGGGCCGGGCGGACCGGGTGGGGGAGGACTGGGTCCTGGACTACAAGACGGACCGCGGGGTGGACGCGAAGGCCTACCTGCTCCAGGTGGGGGTGTACGCCCTAGCCTTGGGGAAGCCGCGGGCCCTGGTGGCGGACCTTCGGGAGGGAAAGCTCTACGAAGGGGCGAGCCAGCAGGTTGAAGAGAAGGCCGAAGAGGTCCTGCGGCGCCTCATGGGCGGCGACAGACCCGAGGCGTAGGGCTCCCGGATCAGCACCCGAAAGGCCCTGAGCAACGCCTTGGGCTTTGTCTCTTTTCCCACTCTACCTCTTCAGCCACTACTGGGAGGGCAAGCCCACGGAGTAGCCGCTGGGAGAGGGCATCCCAGGCCTCCTCAACGACGACCGCATGGGCCGCATGCTGGACACCCTCTACGAGGCGGGGTGACGGAGCGCTTCCTGGAGGTGGCCAAGGTCAGCGAAGCTCCCTTGAGGGCACGCCAGGCCTTCCCCTTCCCGGTGCGGGCCCTGCATGCGGACGCCACCAGCTTCCACGTGCACGGGCGGTACGAGGGGGGAGAGGAGGAAGTGGGGGTTCTCCGCATCGTCCACGGCGACAGCCGGGACCACCGCCCGGACCTGAAGCCGTGGGGGATGGGCCTGGTGTGCGCGGACACGGAGGGGCATCCCCCTCCTCTTCGCTCCCCAGGACGGGAAGGCCAGCGACGCCAAGACCCTGGTGGCCCTGTTGTCCCGCTTCCGGGAGGCCCAGGGCCTCTTGGCGGAGGTCTTTCCTGAAGGGGCCTGGACCCCCCTCCTCCCGGGGTACCAGGGGGTGGAGGTGGAGGCGGGGAAGGCCCTGGGGAGGCTTTTGGCCCGGGAGTTCTCTTGCGAGGTGGACGCCCAAAAGGCCCTGGAGGGGGTGAGCCGGGGCTTTCCTACCCCAGACCCCCTTCACCTAAAGGCCACCACAAGGTCCTTTTCCAGGGCCTCGGCCACCCTGCGCAGGGTGCTCAGGGTGTGGCCGAAGTACAGGGGGTCTAGAATCCGGGTCACCACGGAAGGGGGAACCCCCATGCGCTCGGCCAGGTCCTTCCGCTTGAGGCCCTTACGGCGAAGGGCCTTCTCGATGGCGAGGCTGACGGGGTTCACCGGGCTCGGCCGGATTTCCACGGGGATGAGGCGGTCCCGCTCCTCCTCCAGGTCCGGAGGGGGAGTGGCGCCGGGCCTGGGAAAGGGGCGCTCCTCCACCTCCAGGTGGGCGAGGTAGTAGGCCACTCCCTCCTCCAAGGCCTTCCGCGCCTCCTCTACGCTGGCCTTTCCCGCCACGAAGACGGGAAGGTCCACGCAGAAACCGCCGTAGGTGCCGGATTCGGGATCGTGCTCGATGTAGCAGGGGTAAGTTACGTCCCAAGATCTAACCATGGTTGAAAGCCTCCAGGACAACCACCTCAAACCGGCGTGCCCTTTTTGCTTCTGGACCAGGGCGCCGAAGCGCCCCGGCCGCGCCTACTGCCTCACCTCCTCTTCCGGTATCCCGGCCTGGCGGAGGATACCCTTGAGGGTGCCGATGGGAACGATATCCTTGTCGTGAACGGCGATAACCACTTCCATACCTTGCGGGTTGCGCCAGACCTCGTGGGATCCCTTTCCCCTCCCCTTGATGGGGGCGAAGCCGTGCCTCCGGAGAAGCCTGCGGAGCTCCCTGCCGCTCAGCCTCTTTAAACGGCCTATGGTACCTCCTTTCCGGGCCTGGGGATGGGACCCTGGGGCCCACGAGACAGGTTAGCAAAAATGCTAAAGCATGTCTAGCTCCTCTGACGAACTGAGCTCTCATAAGAACTCCCCCTGGGTTTTTGTATGGGGGTATGCGGCTGACCAAACACCAACGCCGCCCCCGGCTGGAGCTCAAGCTGCGGCCTCACCCGGACAACCTCGGACACAGGTTGGGCCTGAAGCCGGTGTACCGGCGGGTGTGGGCGCCCCGGGGGAAGACGCCCCTGGCCTGGGTGCGGCCGCGGTACCGGTGGCTGTACGTGTACGGCTTCGCGCGGCCGAGCACGGGGGAGAGCGAGTTCTGGCTTTTGCCCCCGGTGAACGCCGCGGCCTTCTCGGAGGTGCTAAGGCAGTTTGCCCGGTTGCGGGGGTCTGGGGAGAGGAAGCTCTTGCTGGTGATTCTAGACCGGGCGGGGTGGCACGTTTCGGGGCGGGTGGAGGTGCCGGAGGGGGTGGGCTTGGTCTTCCTGCCCCCTTACTCTCCCGAGCTCCAACCCGTAGAGCGGGTGTGGCCCTTGGTGAACGAGGCGGTGGCCGAGCGGTGCCTGGTCCTTGCCCAGGACCCCGAGACCCTCAGGCGGCGCACCCTGTTCCACTGGTGGCCCAGAACGAAGGCATCAGCATATACCCCTTCTTATTCTTAGAGGGGTCCAAATTTGGGGTAGCCCTTCAGGTCGCCTTTTATATGCTGAGGAGAGGGGCTAAGGTGGACGGTCAAAAGGCCTTCGGGGTGGTCCTTCTAGGGCTCATCGCCCTTTACTTCGCCCTTCAGGGGCGTGAGGGGCCCTCGGCTTCTTCTCACCAAGGAGAGGCCTCCCCCACGTGCCAGGCCCGGGTGTGGGCCGCCACCCTGGGCTACCAGGAGGTGCGGCTCCAGCTTGAAGGGCAGGCCTCCCTCATCCGCCTGGCGTGGCCCCAGGGGGGCCTCGAGGTGGAAACCCCCAAGGTGTGCTCGGCGGGGGAGTGCCGGGTGCCCATCCCCCCCGGAGTGAGGCCCGTGGAGGTGAGGGTGGACGCGTGCCCCCCTATCCGCCTGGGGGAGTGAAGGCCTGGGGTCAGCCCCTCCCTTCCAGGGGGGTACCCTTACCACGGTCAGGCCCTCCTTCTTGGCCGCCCGGTAGAGGGTTCGGTCAAAGGTGAGGAGGGCGGTGTCCGGGTAGAGCCCTTTGAGGAAGAGGGCCCCTTCCAGATGGACCGCATCCGCCCCCCTTTCGCATAGGCGGGCCGCCCTCATGTGGCCTTCCAGGGTGGGGGTGAGGACTTCCAGGTACTCCCAGAGCTCGTAGAGTTCCCGGAGGGCCTTGCGGTAGAGGGGACGGGTGAGCCTGCCGTCCCTCTGCATGGCGTGGAAGACCCCCACCGCTTCCGGGAGGGCGAAGGCGCTCGCCGCGTGGGCTTGAGCCTGGGAGAAGGCTTCTCGGGCCAAGTCGGAAAGGTCCTCCCGGAGGAGGACCTTGAGGAGGCCGCTGGTTTCCAGGAAGAGCCTCAACGCCTTTGCTCCTGGAGGTAGGCGAGGCTGGGCTTCCCGGGCTTGGGCGCCACGGGCTCAGGGAGGGGAGGCTTCCCCTTCTTGCGGGGAGGGGTGATGAGGAAAGGGGCCTCCTCCTGGGTTTTGGGGCGCGTCTTTCTCGGCATGTCCTTAGTCTACCTGGGCAAGAGGCCCGGGCGGAGTGCCGGGTCAGGGTGTTTCCTTCCGGTACGAGGGAAGCGCCTGTCCCGGAGCGACCTCGCCCGGCGCATGGGGGTGAAGCCTCCGGTGACCACGCCCATCTTTGACCCCCTTTACTTCGGCCACGGCCTGGCGACCCCGCGTGAGGGGCGAGGGCCCCCAGCCCTCGCCGAGGAGTCCAGGACCCCTTATCCCCGCTCCAGGTAGCCTAAGCCCAGGGCCTTGAGGGCCTGCACCCGGAGATCTCCTTGGCACCACCCCCGCGGTCACTTCCACCAGGGTCCACACCCTCTCCAGGTAGGCCGCCAGGGCCCCTGGCTCCTCTACGCCCCCCACCACGTACCCTAGCCCCGGGGGGCCTCACGGGCTGACGGCAAGGACCTGCGCACCAGTGTGGACTTGGGTTGACCAGTTGTGCCCCCGGATCATTCCCCTGGCCTCTTCGTCCAGCCCCACTCCAGCGGAGGCGTGCGCGGTCGTCCCCTGAGGGCGGGGTGCCTCACCCCTCCTCCCCCCACCCCGGCACCACGAGGCTCTTCATCCCGGTCCAGTAGGCCACCTTCTCCCTGGGGTGGCCTTCTTTGAGGAAGCGGCGGATGGCCCGCCAGCGCAAGGGGAGGGCGAGGTCGGCCCGCCGCTTGCCCTCCGCCTTCACCCCGGCGAAGTCCGCGAACTCGGTGAGGATCCACTTGGCCTCCCCCAGGCCAAGGGGCTTCCCCCGGTTCTTCCCCGGGGCGGGCTTGAGGAGGAGGTGGGGGTAGGGGAGGGGCTGGTGGGAGGCGAGGAAGGCCCTCTGGGGGAGCCAGTCGGCGAGGACCTCCCGGGCGAGGGGGGAGAGGGGGACTTCCCGGAGCTTGGTCCCCCGCACCAGTAGGCTCTTCTCCCGCACGTCCTCCTTCCAGAGGTCCGCCACCTCCTTCACCGTGAGGCCCACCTCCCCCAGGAGGACGAGGAGGACCCGGAGGAGGGGACGCCAGTAGGCGAGGGGATAGGCCCCGGCCTTTTCCAGGAGGTCCTGGTAGGCCTCCTCGGGCATGGCCCGGGAGGGGGCGACCACGGGGAGCTCCTGGCGGGAGGGGAGGCGCACGTGGGACGGCATGGGATGTCCGGCCCAGTCCAGGAAGGGGAAGAGGTGCCTGAGGCTCGCCCGGGCCCGCTCCACGGTGCCCCAGGAGAGGGGCCCCCTTTCCCCCCCGGGGAAGCCCCTCTCCTTGGCCTCCAGGAGGAAGGCCTTGGGGTCCTCGGGCTCCAGATGGGGCCACCGCCTCCCCTTGAGGGCGAGCCAGCGGACGAAGTAGCCCACGTAATGGGGGGCCGCCCGGTCGGGCTTCTTGCGGTGGCGCACAAGGTAGGCCCAGAGGGCCTCCTTAAGGACCCCCTCGTCCCAGCGCTCCAGCGCCTCCCCCACCACCCGCCTCCGCTCCTCGGGGTGGTCCCAGACCTCCAGCCCAAGTCCTTCTCTCATCCTCACTCCCATCTTATCACCCCACCTCCCCAACCACAACCAAATCCCGCTTCTTCCCCCCACTCCTTCCCATTCCCCTCTTCTTTCTCTCCCTTCTCTACCTCATTTCCCACGCCCTGAACCCTCTTCCCGCGAGGGCTGAGGGGGCGGGGTGGGGGAGGGGTGCAAAGCCAGCATGAAAGTGAGGAGAAGAGATGGAAAATCCCAAGCCCGATAGATGGGGCACTGCCGTCAGGTCCCCCTCCGGGGCTGGGCCACGCAACGCAGGAGGCTTCCACCCCCACCAGGGCCCCCGGTACCGCTATCCCAACGGGAGCGGGGCCTCCTGGAGCTCTTCCGCCAGGCCCCCCAGTGGCGGGTGGCGTAGGCCGCCCAAGCCTGGGGTGTTTGGGCCAAGGCTTGCTCAGGCCCGTGGTAGATTCCTTCGTGTGCTACTTGATCTGGACCCTCGGGATGTGAAAAAAGAGGGGGTGCTATGCAGCAAGATCGTGAGCACCCCCTTTACTATCTTGACGCGGAAACCCTTCTGGTGGCTACCTACATTTGGGTGGATGACGAACTCAAGGCCTTGCAAGCTCAGGACTTCAAGCTCCCCCCAAAGCAAAAGCACCAGAAGGCTACCCTGGCCGAGCTCCTAACCCTCGCCATCTTTCTCCTTTTGCAAGGCCAAGACCTCGCCAAAGGCTACCTCGCGGCCAAGACCACCCTCAAGGCCTACTTCCCCTCCCTCCCCCACCTCTCCCGCTTCTACCGGGTCCTTCAGAAGGCCCAGGGGTTGTTGGCTCACCTGGCCATGAGGCTCTCTGGGGGACAAGGCCTCCTGCAGGTGGTGGACCTCAAGCCTATCCCCCTGGCCCACGGCCACCGCATCCACGGCCTCTCTCTTCCCGAGGCCGCGATGGGGGTAGGACCTCTGGGGGCTTTCGCGGGCTACGTCCACAAGCTGTTTCCCTGACGGGAAAGCATCATGCCAGTGATGAACGAGCGGGGTCTCTTCTTTCGTTGGGCCATTCTCCCCGGTAATGCCCGGGAGACCTGGGGGAGGGACCTGCTGGACGGTCTGCCCGCGGTCCTCGGGGACCGGGGCTTTCGTTGGGTCCAGGGAGTCAAGACACCACCCTATCGGGTCAGGGGAGGAAGGGTGGTGGAGACGGGGTGGAGAGGGTGGATGGGAAGGGTACGGAACTGGATAGAGACCAGCTTCAGCGTGATGGTGCGGTCTTCGGGGCTTCATCGGATAGAGGCCCGGTCCTACTGGGGGCTGGTGGCCCGGGTGAACCTCATCCTGCTTGTTCACAACCTCATACGTAGCCGGGTGCTTCTCAGGATGGCCGGGGTGGAGCTATGAGGTAGCACACGAAGGGATTTCATCAGGGAGCGGGAGAAAGACGTGCTAGCAGAAATAGCGAAGAAGCTTAGCTGCTAGGGAGAGGCCCTCGAGGCGGAAGGGCCCCCCTTCCCGGGGCAGGGCAAGGCTCCGGCAAGCGCCCCCCTCGGAGCAAGCCGAGAGCACCACCCGGGCGGGAAGGGCCTCCACCTGGACCTCCGCCGTGGCCCAGGCCCCACCCCCTTCCAGGCGCACCCGGTAGGCCCCGGGGGGCCGTCCCCATGGGTACCCGCACCCGGAGGTAGGCCGCGCCCTGGGGGGCGGCCTGGTATGATGATGTGTGATATGCGGGTGACCATCTACCTTCCCGACCACCTGGCCCAGGAGGTGGAGGCCTACCGCAAGGCCCGCCCCGGCCTCAGCCTCTCCGCCCTGGTGCGGGAGCTCCTGGAGCGGGAGCTCGTCAAGCGCCCGGAGGCCCTCCTGGAGGTTGCGGGGCTGGTGGAGAGGGCCGAGCTTTCCGCCCGGGAGCACGACGCCCTCATCCGCGAGGAGCGGTGATCCCAGAGCGGCTGGTCTTGGACGCGGGGCCCCTCATCGCCCTCCTCCACCGCTCCGACCCGGACCACGAGGAGGCGGTGAGGGGCTTCCGCCGCCTCGCCGAGGGCGGCGCCCGGCTCTTCCTGCCCATGCCCGTCCTCTTTGAGGTGTTCAAGTGGCTCCTCTTCCAGGCGGGACCGAAGGCGGCGCGGGAGGGCCTGGCCAAGGTAGAGGAGGGGGTGGTGGTGGTGCCCTTCACCCTGGAAGACCTGGAGGAAGTGCGCCTCCTCCTCGCCCGGCTGCCCGGATGGGGGGGCACCCTGGAGGACGCGGGCGTGGCCCTCCTCGCCCTGCGGCTTGGGGCGCCCGTTTGGACGCTGAACTACCGGGACCTGGGGGCCTTTCCCGCCCTCCGCTTCTGGACCCCGTGATGGGGTTACCTGGCGGCGGCAGCGGTGCTGGCCCTCCTGCCCCCAGAGCTCTGGGGCCGGGCAAAGAGGGCGGCCTCCTACGCGGGGCTGATCCCCGAGCGGGAGGAGTCGGGAAAGAGCGTGGAGAGGAGTCGGCTCTCCAAGAAAGGACCCCCCCTCCTGCGGCGAAAGCTCTACATGGGCGCCCTGGTGGCAGTGCGCCATGACCCGGAGATGCGGGCCTTCTACCACCGCCTGCTCTCGCGGGGAAAGAGAAAGAAGCAGGCGTTGGTGGCCGTGGCCCACAAGCTCCTCAGGCGGATGATGGGCAGGCTCAGGGAGTACTACGCAACCCAGCCATACCAAGAGGTCGCTTGACAGGCAAGACAGTATCAATCCTCTACGAGGCTAACGAGGTTTGCAACCCTCTCTGCCGCGAGCATCCTTCACCTCCAAAGGAAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACACCTCCAAAAACCTGCAGAGGAAAGAGCCTCACCAGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACCTACACGAAGCTCTGGAACAGGGGGGGCGGTAAGCTGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGGGTCTCGTCCTTCCCGTCCTTCCTAGGCATACTCGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGGACCTCGCCATTTCCACCAGGGAGGACGCGGACTAGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACTATCACCGACGCCGCCATCGTACAAACCGGGAGTAGGTTTCAATCCTCTACGAGGCTAACGAGGTTTGCAACGGCCCCCTCCAGGAAGCGGCTCCAGGCGGGGGGTCTTGAGGCCATTTTCGCACGCGGGGGGATTATGCGTCAACCTGGAAGAGAAGCCGTGGGACTAAAGTGGGACTTTCCTTCTCCAGGACGAGTGCGCACGCGCACGAGGGGAAAGAACAAGTATGCAATTCAAAAGAACAGCCTTCTGTACAGCAAAAACCCCCGGTTTGGCACAGGGGGTTTGCATAAGGTGGCCTTCGCGCTCGCTAAACGAAGTCGGGGTCCTCGAGGCGCTTCAACCCCTCGTGGCCGATGCGCCAGGTGCGTCCCACCGCCTCCGGGGGCAAGAAGTACACCGCTAAAACGTCCTCCTCCTTGTTGACCAGGGCTTCCAGCTTGCCCTTGAGGTGGGCCCACTGCTCCCGGGTCAACCGGGCTTCAAACACGGAGTACTGCCGCCTTTCGCCAAAGCCCTTGAGCAGCTTGGCAAGCCGCGCCCGGCGACGGTCATCGGGGGTATCGTAGGCGATGACCAGGTACAGTTCCCTCATCGCACCGCAAAGGGCTCGTAGCGGGGAAGCTCCCCTAGGAGGTGCTTGACCAGGATCCGGGCTTGGGCTAAGAGGATTTCGCGATAGGCCAGGCGCTTTCCCAGAAGGGGGTGCTGTATCCGCTCGTTTAGTCGCTCTTCCCAAGCCCTTAAGAACTTGGGCCATGCCTCTTTCCGTAGACGGGGGAAACCTTCGCTGTCGTCAAAGTCCTCGAGGATCACCCGGCGGTTATTGAGGAGGCTTAGAACCACCGAGTCCGCAAGGACGCTCCGGAACTCTTCCATCAGGTCCAACGCCAACGAGGGGCGGCCGTAGCGCACCTCGTGGAGGTAGCCCACGTAGGGGTCAAGCCCGGCCACGAGGAGGGCGCTTTCGCACTGCTTGGCGAGGAGGGTGTAGGCCAGGGAGAGGAGGCTGTTGGCCGGGTCCCGGGGCGGGCGGCGGCTCCGTTCCCCAAAGGCGAACTCTTCCGGCAAAAGCTCTGCAAAGGCCCGGAAGTAGAGGTCGGCGGCCCGACCCTCCGCGCCCCTTAGCGCTTCCTCATCTTGGGCGCGCTCGGCCTCTAAGAGGGCTTCCTTGAGCCCTTCCCAGCCCTCGGCCCCGTTGCGCCTTAGGAAGACGAGGCCATTTCGGATCTTCCCCAAAACGAAGCGCTGGGCCAAGGCGAGCTTCCACGTGGGCTCCAGGTGGGCTTTGAACTGGGCTACCCGAGCAGGAGCGTTCTTGGACGGGGTACGGGTGAGGCCCGCGTAGTAAGTCCCGGTGCGGGAGAGGTAGTGGATACCGACACCCTCTTGGGCGCAGTGCTTGAGGAGGGCTGGGGTTACCACCGCGTTGCCCAGGATCACGATCTCCTCCACCGCGATGAGGGGTTTTTGCAGGAGCACCTCCCGCCCAGCCCGGCGGGACACCTTGAGGGTTCCCCCCTCCTTGGAAAGGTAGGCTTCGTTTTCCAGGACGTAGACTACGCCCACCCCGCCACCCCCTTCCGCCACAGCTCGGGCTGGCAGGCGCCCCGCACGCTACACCCCTCGCACTTGGAGGGGGGAACCTCTACCCTTGGGGGGCGAGGGCTTCGGAGAAGGGCCCGCATTCGGACTACAGCCGCCTCCACGGCGCGAAAGAGCTCTAGGGTGAAAACCACTTCCCGGCGGGTGTGGCTTTTGTGGTAGTAGACGAATCCCCTCCGGGCCTCGATCCCTCTGGATTCTCGGAGACAAAGGGCCTGAGCGGCAAGCTGCACGGCATCGGAGAGGTAGGCCTCTTCCTTGGCCCGGCCCAGTTTGTACTCCACGGGGCAGGCCTCCCCCCGCCGCCACTCCAGCCGATCCACCACCCCGAGAAGCCCAAGCCGGTCCGACCACACCCAAAGCCCGCTCTCCTCCCCCGGCTCGGTGTAGGCCCTTTCGTGGAGGTAGTGGCCCTCAATCAGGTGGTGGTTGGCGTGCGCTTCCCCCAGTACGTACTCCAGATAGAAGCGCCGGGGGCAGTAGACCACCGTGTTCACCTTGGAGAGGGGCAGGTATTCCACGGCTCCCCCATGGCCCATGCCTTAGACTTACCTCGGGGGCGTCGCGCCCTTGGGTGACACGTGTCTGTCACCGAGGGGAGTGACCGAAAGGTTTTAGGTTGAGCCCTGGAGGTGAACCGTGGGCCTGCGGTGGGCTTTGACCCTTCTTGTCCTGGGACTGGCCGCCTGCAACGGTGGTGGGTACAACGCCAGCGGCACCTGGGAAGGTGTGGCCACGAACCGGAACTATCCCTATGACGCTGTGACCGTGCGCTTTATCCTCCACGATCAAGGCGGAGTTCTTTCCGGTTCCCACTACGCCCTCTTAGACGTCGGGTGGGTGGACGTACGTAGGGGAAGTCCGGGGTACCCGCTCGGGCCAGGAGGCCAGCTGGCGCGTGGACGCTCCTAATGGCTACATCTTGGTGGAGGGCGCTTTCCAGGGGGAGGCCTTTCGGGGCACCTATACCGTCGCCGTTTACGGTTCGGGAAACCTTACCGCAACCCTTTTCCTCTCCCGGGCACGCGTTCAGAACTTGGGCTTTCCCCATGGGAAGGGCCCCTTGGCCCAACAGATGGCGGCGCTTCTGGAGGAAGAGCGGTAAGCCGGCTGGTCTCTTGAGAAGGAGGGGTTCGTGGTAGAATGGGCCCAAGCTATGGAAAGCCGCCTGCCGGATTTCCTTCGCCTCCTTAGGGAGAACCCCAGGGGGCTTCCCGTGCGGGAGATCGCCGCCCGGCTCGGAGTGAGGCGGCAGAGCGTCTACCGCCTGAGGGACAAGGCCCAAAGCCTCGGGGTGTGGGTGGAGACCCACGGAGAAAACCCGGCGAACCTGCCAGGTCACCTACAAGAACGCCAAAGGGGAGGTCAAAACCTACCGCTTTGACCCCTACGCCCTCATTGCCCGCGACCCGCACCTCTACCTGGTGGGGGCCAACCACAACTCCCGGCGGGCGGGGCACGACCCCGTGAAGGACCTTAGGCTGGACCAGATCCTGGACCTTCGGCTTACTCGCGAGCGTTTTAGGAAGCCCCGCTTTGACGTGCGGGCCTATGCGCAACACCGCTTCCGGGCCTTCGCCGGGGAGGGTGCTCCCGTGCGGGTCCGGGTGCGCTTTAGCCCTGAGAAGGCGGGCTTCATCCGCCGGACCCGCCGCCACCCCACCCAGGTGGTGGAGGACCTCCCCGACGGGAGCGTGGTCTGGCAGGTGGAGGTGCCCCTCTCCGAGGACCTGGTGCACTTCATCGTGGGCTACGGCCCCCACGCCACCGTGCTGGAGCCCGAGGAGCTGAGGCGGCGGGTGGTGGCCTGGGCCAAGGGGGCGGTGGCGGCAAACGAGGGCGTTTTGTCACCGGAAGGGGTGACGGGACTGGATTAACCTGCCCTGAGGTTAGGATGGAGCGGGTGATGGTACAAGCTTCTACCGTGGCTAGGGCCAAGCGGCTCGTGGCCGACGTGCGTTTCGGCGAGGCTCCTAGGGAAGCCCTCTTGGCCTATAAAGAAGCGCTTGACGAGCCGGAGTTTGGGGCCTTCCTGGAACGGATAGATCCACGGATCGTACGCTACCTGCGCGTGGCGCCTGGGGGTTCGCAGGCCCTCTCTGATCCCAAGGGCAAGGACCTGCTCCTGTACCTCCATCCCTTGCCCGGTGAGCGCCAGATGCGGGCTGCCTACGAGGTGGCCATTGAGGGCTTCCTGGAGCACCTCGAGACCCGGGGCTATCCCGTGGTGGAGCGAGGTGCAGGCTGGGTAAAGGTGTACGTGAGCCCCAAGGCCCCGTCCTTGGACCTCGAGGGGGCCTGGAAGGCCTACATAGAGGAAGCCTTTAGCCTGGAGGGGCTTTCGGCTAGGCTTCTTCCCCTTCTGAACTCCGTGCGGCTAGCCGGGCGGGGCATCAGCGCCCCCAAGGTGCCCGTGCCCACCCTGGGAGCCCGGGACTTCCTCGCCGCCTGGTACCTCGCCAACCTGCTTTCCGTCAAAGAACGCCTAGCCTGGCGGGATCAGGAGATACGCCGCCTAGAGGAGGAGGTTTCCCGCCTTCCTGAAGGTTCGGAGAGGTCCAGGAAGCTCCGGGAGCTGGAAAAGCGGCGGCAGGACCAAGAGAAGGAGCTTAAGAAATACGGGGGGGAGCTTCGGAAGAAGTGGGAAGAAATCGTCCGGAAAGAGGCGGAAAAGGCCGAAAAGCGGCGTAGGCTGGAAGAGCGGCTGCAAAGGGCCAAACCCAAGGATAAAGCCCGCATCCAGGACGAACTCCGGGCCCTCGAGTCTCCCCTCGCCGAGTGGGCTCTAGAGGGTCTGGGAAAAGCCAAAGACGACCCCGGACGGCTTTGGACGTGGCTGGACCCGGAAAGCCCCGAGGCTCCCGGGGCGATCCAGAGGCTTAAGCCGTACCTGGGGCGCTTCGGCCCTTTGGCCAAAGGACAGCTCAACACCGCTGTGGGCAACAAGTTTACCAAGATCCTCGAGGAGCTCCTCCGCCTCCTCAGCCTTTCGTCCCCCGAAGTGGAGGTGCCGCCCCTGGTTTCCGAAACCCCCTTCACCCTGGACCTAAGGGATCCGGGGGATAAAGCCGATGTCTGTTACGGGTGCGGGCGCCCTCTGGGCAAGGACAAGCTCAAGGCCAGCAAGCTGGTGTTCGCCAGCCCAAGCCAGCGCCTGCAAAGCGGAAATGGTCAGGACGAGCCCTGGGTCTGCCCTTCCTGCGCCGCCCTTGCCCTCCTTTCCCCCATCAAACCCGGGGAGGGGAGCGTCTTGGTGCGGGTAGGGAGCTATGGGGCTCCGGAGGCGGCCAAGCACTTCGCCCGCCTCCTGGTTACGGGAACCCTGCACGTGGCAGCCGGGCGCTACCTGCTCCTGAATAGCCCACAGGTGGGGGGGAAGCCCTTGACCCAAGCCTTGGGCCGCGTGGTCTACGCCCTCCAGGCCTTGGGGCAAGAAGTAAACCCCAAGGTCCTGGAGCGCTTTCCCTTCTACCTGGTGGAGGGCGCGCAAGAAATCCCCCTTCCCCCTAGAGCGCTCTGGCTTTCCCACGTCCTGCAAAGGGCCTTTGCCTCCCGGCCGGATGAGGGCGGCGAGGTCAACCGCCCCTTGGGGGAGGCCTTGCGCTATGCCCTGGGCGACCTTCCCTGGCATGCCCTGTACACCTTGGCGCGGCGCTATGGCCGGGTGGCCGATCGGTTTTCGCTGGAGGATGGCCTGATGCGGTATGCGAGCCTTTTGGAAAAGGAGGTGGGCATGAAGGAAAACACGGACCTTTCCCAACGCTTCCGGGACGTGGCCGGCCTCACCGGGCTTCTCAGCGCCTGGGTGGGGTATGTGGAGGGCCAGGTGGGCCGGAACTCCCAGGAAGCCAAACGGGCGGTGGTGAAGCTTCTGGATAACCTGGAGCGCCCTGGGGACTTCCTGTACGTGGCCGCCTACCACCTGGACAGCACCCAGGCCCGGCTTTACGAGGCGGGCGGGGCTTTCTTCTACCAGGAGGCCAAGCGGCTCCTCCAGGAGGCGGGGGCCAGGGCGCAGGAGGCGGAGGAAGGCTCGGGCCGCTTCCTGAACGTCTCCCAGGACGACCTTCACCGGGTTTACGCGCATCTGGCGGCGCGCTATCCGGGCAAGGCCTGGGAAGGGTTTATCTACGAGGTGCGTCTAAGTCTGGCCTCGAGGTTCCCCCAGTACATCCGGATGGAGAAGGAGGGTTAGGATGGCGAGCGGACTCACCCCCAAAGGCGAGGCCCTTTACCACTGGGACATCTACGCCCTGCTCTACGCCCCCCAGGAGGTCTACTTTGGCCACGAGACCCAGGTGAACGTGAACCTCATTGAGACCGTAAGCCTCCCCGACGGGAGCGAGCGGGTTTACCTTTCCCCCACCAAGCGCCGCGGGGTGGAGCGGCGGGCCCTCCTTTACGCTCCCGTGGAGCGGAATGGGCAGCACCTTTACCTCACCGACCTCCTGAACTGCGGCATCCCCAACACCTGTGGCCGGGAGAACTGCCCCGTCTGCCGGGTCTACGGGGCCTTGGTCACGGAGCGGCGGGGGAATATAGAACGCACCACTTTCATCGGCCGGCTCACCCACGGAGGTGGCGTGTCCATACCCGCTTGGCAGCCCCTGGAAAAGCAGCGGGCCATGCACCCTTCCGACCTTAGGCGGGAGTCGGGCGAAGAGCCCCAGCCCTTCAGGCGGCAGTACGGGGCTCCGGGCCTCCTCTTCCCCGTGTACAACCACGTCCTTGCCGCGAGCGAAAGGGAGTTCCGGGCGGTGGCCTACGCCTTCCTGGCAAGCCTTCCTCGGCTCGGGGCGGGCAACCCCAAAGGGCTGGACCTCTACGAGGACGAGACCTTCGGCCCCTACCTGGTCCTGGACCGCTACAAGGCCCCTTTGGGGCGGCGGGTGGTCCTCCCGCCCACCCTTAAGGACCCCGGGGAGGCCCTGGCGGAGTTCCGGCGCAGGGCGGAGGATGCCCCCGAAGGAGGAGCGCTTTTCCAGCGCCACCGGGGGAGGGCGGCCTTGGAGGCGCTTCGGAGGTTGGCCAAGGCTTTTGTGGAGGAGGACCTTCCGGCTCTGGCTTCCGCTTCCTAACATGTACGCCATCGCCCTCAGGATCCGGCCCACCTCAGCCCTCACCTTCCGGGTGCTTCCCGGCTCCATCCTGGACATCGCCACCTACCCCTTCGTCCCGCCCACCACCCTTTCGGGATGGCTAAGGCGGCTCTTCTGGGCCCAGGAGGGCCTCCTTCCCCCGGATCAGAGGGAGGGGAACACCCCCCGCTTCTACGTCCTCCCCCGGCGGTACCTTCCCCTTGGAGCGTACCCCGTGGGGGAGTGGAGGGTCCACCGCACCCATCGGCATGGGCCAAGGGCCTTCACCCACAGCGAGTTTTCCCGCTTGCGCCGGGAAGGCAAGCCCCCCAAGGGAGGGGACCTTCAGCTGCACACTTGGGAGTACCTCCTGGCCGAGGAGTTTTTGGGGGCGGTTTTGGCGGAGAAGGAGGAGGACCTCCGGCGCCTCCAGGGTCTTGTGGGCTACGGGGCCAAGCTGGGCAAGGAGGGCTTCGCCTACCTCGAGGCCGTGGGCGAACCCCTGGAGGTCCGCCTCGAGGAAGGAGATGCGCCCTTCACCCCCGTTCGTGCGGAAGCCTGGGGCGGGGCCATCCAGGGGGCTTACCCCCTCTACCGCTTCCGCTTTGGGGAGGCTGAAGACCCGGACCCCGCAAGCCCCGACCCCAGTCCGGTCATAGGGTACGAGGGGGCCTACTTTGTCCTCCCCCGTGGGCGGGGCCTGGCCAAAGGTTTTTCCTTGGAAGGGCGGTTTTTCGCTTGGGATCTGGTGGAGTTCCTATGGGCGAGGGCATCGGGAGGGTCTTCTTCCTAAAGGACAAGGTGGGCTTCCAGCCCCTTTCCAACCACCAGGGGCTCGTGGTCAAGCTCCTGGAGTCGTGGCGGGAAGGGGATGAGCCCCTGGCGCTTTCTCCAAAGACCAAGGAGCGCCTCCTCCTTGCGGCGCGGTACCACGACGACGGAAAGCGTTTTACCTTCCGCATCGTTCCAGACGGGAAGGGCGGGCTCACCTATAGCTTCCGCGGGCACCGCTTCCGGGTGGCCCAGGCCGTCCAAGACCCCTACGCCCAGGCCCTTATCCGGGGTCACCATGATTACTCCACCCGCGAGGTGGTGAACCTGGCCGCGGACTTCCTCGAGGAGGGCTTGGGCCACCGCTTCCCCGAGGACCTCTTCCTCCTCATGATGGCCGACCAGTTGGAAGCGGAGCTTGCGGTGCGGTTGTGGCAGGGGCAGGCAGGAGAGGTCCGGCCCTTCGTGGAGTTTGACCTGTTACCCGACGGCGAAGGCGGGTTTCTCTTGGACCCGTGGCCCTTCCGGGTGGACGAAGTCGCCCTGGACTTCCTGGTCTACTTCCACCCCTACCGGGGCGAGGAGGCCGAGGTCGTGGAAGGGTGGGGGCGGGCCTTGGTGGGGGCTTTGGAGGAGGGGAAGGTGCCCGAGGCCTTCCAAGAGGAAACACGCCGGGTGCGCCTCAGGCCCTGGGCGGCCGAGGCGAGGAAGGCGGACGACCCCGAGGCCTTCTACGCCCGGTTTGGCCTGGAGCCCACCCCCTTCCAAAGGGAGGTCTTCAAGGTAGCGGAGGGGGACCCCGCCCACCTCCTCCTCGCCCCCACGGGGACGGGGAAGACCGAGGCCGCAGCCTTCCCCGCCCTGGCCCGGGGGGAGCGGCTCGTCTTCGTCCTGCCCACACGGAGCCTCGTGGACGACCTGGAGGGGCGCTTTCGCCGCTATCTCAAAATCCTGGCCCAGGAGGAAGGGCGGCCTAAGGCCTTGGTGGTGGACACCGGCCACCGCCAGGCGCGCTTTCGCTTTAGCCCAGATGGCCAAGAGGAGGCCACCAAGGAGCGGCACCTCTACCACGCCGATGTCATCCTCACCACCTTGGACAAGCTCCTCTACCGCTACTTCGGCTACGCCGAGGGGGTCAAATCCTACACCTTTCCCCGGCGGATCCACGACCGGAGGACGCTTTTCGTCTTTGACGAGGTGCACCTTTACGAGGCCACCGCCTGGGCGAACTTCCGCCACCTGATCGCCTCCTTGTACAAGGCGGGCGTGCGCTTTCTGGTCATGAGCGCCACCATGCCTGGAACGTACCGGGAGGAGCTGCTCCTCGAGGGCACCCTGGAGCACCCTCCGGCCAAGCGGCCAAGCCGGGTGCTCCGCTACATGCCCCAGGGCAACCCCATGGAAATCATCCAAAGCCACCGGGGCAAGCGGGTTTTGGTGGTTCTGGAGGAGGTCAAGGAGGCGGCGGAGCTTTACAAGAGGCTCAAAGGGGAGGGGGTTTTCCTCTACCACGGCCGCCTGGCGGAGGGCCAAAGGAGAAGGGTCTTTGGGGAGGTCAAGCGCCGGGACGAGGCCCAGGAGCCTTACCTTTTAATCACCACTCCCGCCATAGAGGTGGGGGTTGACCTGGACGCAGAGGTTCTGGTCACGACCCTCTGCCCGCCGGAAAACCTTCTGCAACGCCTGGGGAGGGTGAACCGAAGGGGAAGGGGCCAAGGGGAAGCCTACGTGGTGGGGGAAACCTACCCCGACTACCTCGGAAGCCTGCCGGAGGGCTACTTGGAACTCCTAAAGGCGCTGGATGGGCAAGACTTGGCCCAAGGGGGGGAGGAGCGCCTTCGGCAGGCCATCCGCTACCCCAAGTACCTGGACCCCAGGGCGGAAACCTTCTTTGAGGCCCTGCAGGAATACGTCTACGGGCTGGACCTTACCCAAGAACCCCTCCACCGCAAGGGCTTCGTGGCCACCCGGGGTTGGACGCCCAGCGTGCGCCTCCGCCAAGGAGAGGACGAGGTGGAGGTTCCCATAGACCGGCTTGTCGGCAGGAAGGAGGAGCTCACTCCCGTCCGGGTTGTGGAGCGGCTTTTGACCGATGGGGAAAGGGGCAACCGGCGTTGGGAAGAGGTTCCCTTGCGCTCTGGGGAGCTTTACGGACGGGAGCTGGTGGTGGACTACCCCTACCCCTACGACGCAGAGCTGGGCTTTGTGGAGTTGCCCAAGGTGTTTCAGCGCCTTCGCCATCCCGACCCCCAACGGGTCCAGCTCCTCTACGCCCCGGAAAAGGATGCGGGCGAGACGCCGGAAGGCGTTATGGACACCGATCAGGTAACGGGTGGGGGGAGACGGGTTCTCTGGTATCTGGGGGAGTCGGCCTGGGCGGAATCGGCCAAGAGCGGGGAGGTGGCCGAAGAAACCGAGGAAGAGGAAGAAGAGGGGGACTGATGCCCCAGGCCGTGGTCCTCGAGCTCGTGGGGGAGAAACCCCCCCTTTACCCTGGCCGCTATGCCCACGGCCTCTTCTTTGCCCTGCTTTCCCGGGTAAGCCCGGAGCTGGCCCAGAAGCTCCACGAGGCTCCGCGCAAGCCCTTCACCCTGGCGCCGCTTCCCAGGGTTGGCCCCGAAGGGGCTACCTTGAAGGGGATCCTGAGGCTCCGCCTTACCGCCCTGGACGATGGCCTTTTTGCGCCCTTTCTGCGGGCCCTCCTGGAGGCCGCCCCGGATGGGCTTCCCCTGGGGGATAGTTCCTACCGGCTGGCGCGGGTCCTGGCTACCCGCGAGGGGCACCCCCTGGCCGGGGCCACCTCCTGGGAGGAACTCAAGGAGGCCCCCAAGCGGGAAAAGGCTACCTTTCGTTTCCTTACCCCCACGGTCTTCGCCACTTCTAAGCCGGGTGGGCGCACTCGCTACACTCCCTTGCCCGACCCCCGCCTCATCGCAGGCTCCCTCCTGGACAAGTGGCAGGCTCACAGCCCCTTTCCTTACAACCCAAAGGAAGAGGCCGCCTTGCGGGAGCTTTTTGAGTTGGACCTCGAGGTGGCAGGCTTCCGCAACCTGCGCTTCCACCGGGTACAGGCGGGGAAGGGCTTTTTCCCCGGTTTCACGGGTGAGGCGACCCTGAGGCTTTGGAGCCAGAGCCTCGAGGCCCAGGAGGCCCTGGGGCGCCTCCACGCCCTAGCCTTCTTCAGCGGCGTGGGGGCTAAGACCCCCTACGGCATGGGCCTGGCAGTCCCCCTCTAGCGAGCGCGAAGGCCACCTTATGCAAACCCCCGATGCCATATCGGGGGTTTGTGCTGTACAGAAGACTGCTCTTTTGGATTGCATACTCGCCCTTTCCCCTCGTTCGCGTGCGCACTCGTCCTGGAGAAGGAAAGTCCCACTTTAGTCCCACGGCGCCTCCCCTAGCTTGACGCATAATCCCCCCGCGTGCGAAAATGGCCTCAAGACCCCCCGCCTGGAGCCGCTTCCTGGAGGGGGCCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACATTAGTCACGGCCCAAATGGCCGACGGCGACTACGAGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCCGTTTAGAAAGCCAGCTTCTGAGCGCCCCTGAGGGAGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACTCCCGTGGCCTCCAGGGCCTCGGCTCCTCCCTCGGGGGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACAACTCCCCGGCGAGATGGGCCACAGAGCGAACCCCTTGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCACTACCTAGTGCACCAGATGCACTAGTCTCGGGGCTGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACGCCGTGCGGCGTGCCGGGTGGTCTACGGCCCCCCGCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACACTACCAAGGGGCGAGAGGAGAGATTTGGTTCGGGAGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCCCGTAGCCGCCATTTGCTTTCCAAGCCACCACCTGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACTTCTCGCACCCCTCCTCCTCGGCGCGTGGGTCCACCACGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCAGATCTACCTCGGCCCGGGCGCCCTCGTGGACCCCGTTGCAAACCTCGTTAGCCTCGTAGAGGATTGAAACCCGAGATAAAAGCCGGTCGTGTAAGGATTTATGTGTAAGGGTCCGTGTTTAATAGGGGGGCACACCTTAGCACGAGGAGGTGCCCCGTGGACCAGGATACCTTGCGGATCTTGCTGAGGGAAGCGGTGCGGGAGACGGTGGCCGAGGTTCTGCAGACGGTTCTGGAGCTGGACCGGACAGCCTTCTTGCAGGTGCACGGGGGGCGCAGGAACGGCTACTACCCCCGCAAGCTGGAGACCACCTTCGGCCAGGTGGACCTGAAGGTCCCTAGGGATCGGGAATCTCGGTATTACCCGGCTTTCCTTAAGCCCTACGCCCGCCGCCTGGTGGACGTGGGGGAAGTAGCTGTGGCCTTGTACGCCGCCGGGGTCAGTCAGCGCAAGGCGGCCGAGATATTGAGCCTGCTCTTAGGCCACCGCTACTCCCACGAGACCCTGAGCGCTCTGACCGACCAAGTCCTGGAGGCGGCAGGAGCCTTCCGCACCCGGCCTTTGCCCGAGGAGATGGCCTTCGTCTACCTGGACGGGCTTTCCCTAAAGGTCTTCAGGGAAGGAGAAGGGATCGTGCGGGAAAGCGTGTATGTGGCCCTGGGCATCGCCCCTGATGGGGAGAGACGGGTCCTGGGGTTTTGGCTGTTGCCCACGGAGAGCGCCCTGGGATGGGAGGGGGTCCTGGGGGAGCTTTGGCAGCGGGGCCTGCGGCGGGTATTGCTCTTCATCACCGACGGGCTGCCCGGGCTTCCTGAAGCGATCCGCAGGGTCTACCCTCAGGCGGAATGGCAGCGGTGCGTGGTGCACGGGGTGCGGTGGAGCCTGTCCCAGGTGCGGGCGCGGGACCGGGGCCTGCTGGCGGAGGACCTGAGGCGGGTGTACGGGGCGGAGAGCCGGGAAGAAGCTCTTGGGGCCTTGGAGTCAGCCCCGAAGGGGCTACCTTGGGGAGGTGAAGGCCGCCTGGGGTTCGCGGTACCCGGGGGTGGTGGGGCTTTGGGTACAGGATTCGGGGGCCTTCCTGCGGTTCTACGGGTACCCCAAGGTGCTTTGGCCGTACCTGCGGAGCACCAACCTGATGGAGCGGTTTATCCGGGAGCTACGGCGGGGGACGAAGGTGCGGGACCACAAGTTTCCTAAGGAAGAGGCGGTGTACAAGCTTCTTTACCTGGAGTCGGAGAGGCAGGCTGCTTCGCGAAGCGAACATCTTGCAGGGAGGTGGGCAGAACGGAAACTAAAGGGGTTCTCGGAGGTGAAGGAGGTGCTGGAGAAGATGCTTCAGGAGCGGTATGCCCCCCGTACACAGACTCTTACACATAACTCTTGACACGACCTGGGGCTCTATGCGGTATAACGGTCAAGTCTGAATAAGTGGGAAACAAAGAAACACGACTTTTTGGTATACTAACACCATGGAGCTGGCCAAACTCAGCCGCAAGGGCCAACTCTCCATCCCTAAGCGCCTCCTCAAGGCCTTGGGCGTAGAGGGGGAGGCCTACTTCCTGGTGGAACTCGCTCCCGAGGGAGGCCTTCTCCTGCGCCCCGCCGGGGTCTACCCCTTAGAGGTCTACACGGAAGAGCGCCTCCAGGAACTCCTGGCCGAGGACACCCTCACCGAGGAGGAGCGCACCCGCCTTGCCGCCCTCGCCCGTTAGGCTCCACCGCCTCTTCCTGGACGCCAACGTCCTCTTCGCTGCTTGCTGGCAAGAGGGGAGAGCGCAGGCCCTTTTGGAGCTGGCGCCGAGGGCCAAGGTCCTCCTCCTCACCTCTCCCCACGCCCTGGAGGAGGCCCGGCGCAACCTGGAGGCCAAGCGGCCCGAGGCCCTGGAGTGCCTTCAGCGGATACGGGAACGGGTGCAGACGGTCCCCGAGGCCCCTATGGCGTTGGTGCGGAAAGCGCTGGCAGAAGGCCTACCCCTTAAGGATGCCCCGATCCTGGCGGCTGCCTGGAAGGCCGGCGCCGAGGCCCTGGTGACCGGGGACCGGCGCCACTTTGGACACCTCATGGGGAGGAGGGTGAGGGGGCTCTGGGTGGTTTCGCTGGCGGAAGCCCTGGCGGGGGTGATGGGCCTCTTGGAGGACAAGGGTTAGGGGGAAAAGGCCTCAAGCCCGAACGGACGCCAAACCCCATTCCTCCGCCTGCGGCGGGTGAAGGGCTACGGGGTGGTGGTGGTGGTGGACACGCCCCCCGCCCTCCGCTCCGAGGCCCTGGAGGCGGTGCTCAGGGCGGCGGACTACGCCGTCCTCCCCACGCCCCCCGCCCCCCTGGACCTCGAGGCCCTGGTGGAGACGGTGCGGCGGGCCGTCCGCCCCCTCGGGGTGGCCCACCGGGTCCTCCTCACCCGGGTGGACCCCCGGAGCCTGGGGGAGGCCCTCGAGGCCCAGACCGCCCTCATGGAGGCCGGGGTGCCCGCCTTCCACGCCTTCGTACGGGCCTACAAGGCCCACGAGCGGGCCGCCCTGGACGGCAAGCCCATCACCCGCTGGCGCGGCCCCAACGCCCGGGAGGCGGAGGCGGACTACCGCCGGGTGGCGGAGGAGCTCCTCAGGGAGCTCGCCCGGACCCCGGAAAGGAGGGAGGCGTGAAGCGGAAGCGCCTGGCGGAGCTGGTGAGGGAGGAGGCGGGGGACCTTCAGGAGGCTCCCGCCCCCAGGGAGGAGAGGCCCGGGGAAGCCCCTCACGGGGGGGGCCTCGAGGGCTCCCCGCCGGGCGAGGGCCAAGGGGAGCGCCCCCTCCCCCCCTACCTCACCTACGTCCGCAAGGAGTGCCGCCTCCGCCCCGACCAGCTGGACGCCCTCACCGCCCTGGCCCGGAGGCTCAACCGGGAGAGGAGGGGGAAGGGGGAAAGGATCACGGAGAACACCCTCATCCGGTGGGCGGTGGACATGTTGTTGGAAAATTACCGCAATAGCGACATCTTTCACTCCGAGGACAAGGGGGATTGAACGAGGGCAAGCCAGAGGTAATGGGTGGGAGGTAATGGGTGGGATTTCACCCCACCACGTCCGGCAGCGCCCGGGCGGCCTCCTCCAGGCGCTTGCGGGACACGTGCACGTAGACCTGGGTGGTGCTGATGGAGCTGTGGCCCAGAAGCTCCTTCACCTCGTCTATCCCCCGCCCCGCCTCCACCAGGGCGCTGGCGTAGGAGTGCCGGAGCTTGTGGGGGGTGATGCGCCGCCAGTCCTTGAGCCCCGCCCGCCTCGCCACCCGCTTCACCATGGCCTCCACCGCCCGGGCGGAGAAGGGCTTCCCCCGGTTGGGCCCCGTGGTGTGGCTCCAGATGTAGGGGCTCGTGGGGTGGCCCTCGAGGTTCCGGTGCTTGAGCCACTGGTGGAGGGCCCTTTGAGCCGTGGGGGAGAGGACCACCACCCGCTCCTTACCCCCCTTCCCCTGGACCCGGATGGCGTGGGGGATGCCGTCCTGGTAGGTGATGTCGGCGTAGGTCAGGGCCAGGGCCTCGGAGAGGCGGAGGCCCGTGCCGTAGAGGAAGGCGAGGAGGGCCCAGTCCCGCAGGGCCACCCGGGGGGAGCGGTTCTGGTAGGCCGCCTGGAGGAGGCGGGCCACCTCGGGCGGGGTGAGGTAGACCGGGAGCCTCCTAGGGAGCTTGGGCCGCTTGACCCCCTCCGTGGGGTCCTTGAGGATGGGTAGGCCCTCCACCTCAGCCAGGTAGCGGAAGAGCTTCCTCAAGGAGGCCAGGACGCGCCCCGCCCTGTGGGGGCTCACCTCCCGGGAGGCCAGGAAGGCGCGGATGTGCTGGCTCCCCACCTCCTCAAAGCGGGGGGGCCTGCCGTGGCGCTCCCGGAACCAGCGGGCGAAGAGGCCCGCGTCCATGAGGTACTCCTTGGCGGTGCGGGGGGAGCGGCCCTCCTCCATCTCCAGGTACCGGCGGAAGCGGTGGAGGAGCTCGGCGTGGGGGTCTTGGGCGGCTACCATGTTCAGACCTCCTCAAAGGCGGGAACGGGCACGGTGGGGACCAGGTCCCGGGCCACGAGGTAGAGCCTGCGGTCCAGGGTGAAGAAGCGCCCCTTCCCCTCCTTCTCCCAGAGCCAGGCGAAGGAGGCGAGCTGGAGGGCGTCCGCTCCCCTCAGGGGGTGCTCCTCGGCCAAGGCGCCCGCCAGCTGGACCACGGGAGGGCTCAGGGGCACCCGGAGGAAGGCGGGCCAGTCGGCCCGGAAGGCCGCGCTCAGGGAAGCCTGGCGGCGGGAGGTGATGGCCCTTCCCCGGCGCAGGGCGTGGAAGGTGGCCAGGGTCTCCACGTAGGCCAGGTGGGAGGCGGCGAGGAGGGTCCCGGGGCGCTGAGCCAGGTCCACGGCCCACTCAAAGGGGTCCTCGGGCTCCAGGTAGTAAAGGCGCACCAGGACGCTGGTGTCCAGGAAGAGGGGCTCAGCGTCGGAGGTCCTGGAGGACGGCATCCAGGGGTACCCCCTTCACCCGGGGACGCCAGGGCTTGAAGCGGGGCTTGGGCCCCTCCGGGGGCTCCAGGGCCACCGCCTCCGCCAAGCGCCGCCACTCGGGCGCCTTGAGCAGGGCCTTCAGTCGGGGCTCCTTGGTCTTGGGCATGGCTCCATTCTACCCTTCCGGGGGAGGGTGCCCTCGAGGGCCCCCGCCCCCGCTTTCCCGAAGTATAGCATTCGCAAAAGATTCGTTTGGCGAAGTGTCGGAGGGAGGCCCAGACCGAGGAAGAGCCCCGTCCGGGAGGGCGAAAACCCCCGAAAAAAGGGCGGGCAAGGAGCCGGGGCGGCCGGCGGAGGGTTGCGACAAACGACGGAAGTTTGCGACAAACTCACAGACTTCCAGACTTACAGACTTCCAGAGTCTGGATGTCTGGAAATGCACTTCCCGGTACGGCGGGTAACATGGGTGTATGCCCAGGGACGCCCTGAAACCGGAGGTCCTGGAACACTACCTGCGCCTGGCCCAGGAGGTGGCCCCACCCACCTCCAAGGGCAACGGGGCCGCCCCTGGCGCTACAGCCACGCCCGCAAGGTGTTCCCCTGACGGGGAAGCGGTTACCTGGCCCTCCTTCCCTACCGCGCCTTCTTCCGCCTCACCTGCCGCAAGACGGAGGCCTCTCTCCAAGACCTGATGGAGGAGCCCTTCCCCTCCCACCAGTCCCTGGCCCGCTATGCCGTACAGCACCTGGACCCCGAACTCCTTGAGGCTCTCCTGGAGAGGCTTTCCCGGGAGCTGGAGGCCCACCTTGCCCCGGGGTCCTCGCCAGAGGAGGAAGGCGCTTCGGGCGAGGCCGGGGACGAGGCGCGGGTGAGGGGGGGTTTGGGGGGATGAAGACGCGGCTAGGTGGGGGATACCTGATGGAGCGGAGGCCTTGGACGGCCATGGCGCGGGCCTCTTTGGAGCTGATCGCCTACGGCCTTAGGGTTCTTCTCTCCCTCCTTCCCCCGCCTCCGGGGTGCAAGGCGATTTGCTAGGCAAGCCCTGGACCAGGTGTCCAGGTAGGGGTCAAACTCCCCCACGGGGCCGAAGGCGAAGGCCTCGAGTTCCTCCCACGGCCTCCTTGCCGCGAGCCAGAGGAGCCTTAGGCGGTTCAGCCCCTCGGTGGTGGGGCCGCCCGCGTAGGCCTCCGCCGCCTCCGCGAGCACTCCCGTTCCCCCGGCAAGCCCCAGGAGAAGGGGCCCTACCGTTTGGCGGAGGTCCGCCTTGAAGCCTTAGGCCAGGGCCACGCGGAACAACACCAAACCGATGCCGATCCGTCTCATCGCTTCCCTCCCTGCGTTTCGGACGGGGCCTTGGGGCCTTCGGGGGATGGCCTATCCATCAGGAGAAGGAGGAGGGCCGCCTTGAGGTGGGCGCGCCTCGGGACGGGGCTCTGCGCGGGGTCGGCGGGGAAGGGGGGCCTCGCCCCCTCGCCCGTGCCCTCCCTCCGGCCGAAAAGCGAGGCCTTACGCATCCTGGCCCTCCGAGTCCAGGACCACCTCAAAGGCCTCCAGCCTGCTCGGCCCCAGGAAGGCCTCCTTGGGCAGGGTGCCGCTCCGGGCGTGCCCCTCCTTGAAGGCGGGGCTTTCCGTCCAGGCCCGGAAGGCCTCCTCGCTCTCCCAGAGGGTCATGACGACGTAGGGGTCCCCCGGGTCCTTGGGCCTCAGGACCAGGTTGCGGATAAAGCCCGGCATCCGGTCCACGAGCCGGGCCCTCTGCCGGAAGGCCTCCTCAAACTGCTCGGCGTACTCGGGCCGCACGGGGATGCGGTTCATCGTCACGAACACGGGCGCACCTCCTGGAGGCCAGGCTAGCCGGGGAAGGGGAAAAAGTAAAGTATTCCACTCGGATTTTATGGATATTGGGAACGATAACTCCTCGCAACACGCCGGAACCACGCAGTGGTGCACTCAGGCCACCCTCGGGGGTGGAGCGTGCGGCTTGGCTTGTGGTAGGCGGAAAGGCGGGCGTCTCCAAGAGGCGCCGCCACACCCCGCGGGAAGCGGACCTGTAGAGCCTTCAGCGCTTCCGAGGACCAGCGAAAAGAGGGCGCCTGCGGCCTTGCGGACCATCCGGCTTCGGCTCAGGAGGTCCAGGACCAAGCTCTTGGGGGAAAGAGGAGCCGGGCGCGCACCGGCTCCAGGCCGGAAGAGAAGCTGGTCGTGGAGGAGGATGACCAGGAGCGGTCCTCAAGCTCCCCAAGGCGGCCTACCGTTATCCCGTGGTGCGGCGGGGCGACAGGCTGGAAGCCTTCGTGGTCAAGGTGGGAAAGCGGGTCTACAGCCTGGGCGTCCTCCTCAAGAACCGGCATGGGCCCTTGGGGGAGGACGGAAGTGAAGGCGGCGGTAAGCGGCCCCGGGTCGCCTGGGTTTCTTGCCGGATAACCGGCAGGAACCCCTTCCTTTTGAAGGGAGGGCCGCAGTCCTTGGGGAAGGGGTAGGTGCCCGAAAGGCTTCTCCGCCCTTTCTAGTACCGATGAATTTCCAAGAAACTGCAGGGCGGGGCAGTGGGGTCTCTTTTTCGCGAAACGTAGCTTTCGCGAAAATAGGGCCCCCAAAGGGGGTTCTTGTCCCTCCGGGCGGCGAGGCAGGCGCTTTTGGCCGTAGCGCACAAGCTGTTGCGCGAACGATGGGACGGCTCAGGGAGCACTACGCGACCCAGCCGCACCAAGAGGTCGCTTGACAAGCAAGACAGTATCAATCCCCTTACGGGGCTCAATCCCTTGCAACGATGACTCCAAGCCCATTGCTAAGGTTGGTTGACGACTATGAGTTCGGTCGCAATCCCCTTACGGGGCTCAATCCCTTGCAACTGTACCCCCCAAAGAACCCCGTCCTGGACAGCGCCGCTAGAGGGGGGGTTTGTGAGAAAGATGAAGCTTGGAATATACACACGGCGAATAACAGGGGTTTTTGAGGATTTACACCGATGCAAAGCCACAAGAGGAAGGGGCGATGAAAAGAAAAAGTGCATATTCGCCTTCCGCAAGGGAAAAACCGGCTTTCAAGATCCCCGTCCGGTGGTCCGGACAAGGGCATTATAGCATCTCGCTGAAACGGTGCACCCCGTCCAAAATTGCCCAAAAAGCCCCTTTTCCAACTTACTTCGCTTTGTGAAAGCGTGAAAAACGCCTGTTCCGTCGTGTCAAGTACCCCCTAGCCCCGAAGGTAAAAGGGCGTGCACTCCCCCCGCCCCAGAAAGGCCACCTTCAGCCTACGGGCTGGCCCGTGCCCATGCCCCCCAAGGGGCTGGCGGCCCAATTTTTGGACGGGTGCACGCTCCATGCCCCGTCCCCCGACGGGAAAACCCCTTGGAGGGTGTCTGGCGAATTCCCACCTGTAGGTAGGTTGTCGCCGGGCAGCCTCCCCCAGGCCTCTTCGGGATAGGGCCCTCGAGCCCCTTTCCCCTCCCCTCCTTTCCCCCCTTCGGGGCCTTCTTTGCTTCCTCCTCGAGGCCCCTGGTCCTGTTTCCCTAGGGGGGCTCGAGGTGCCTTCCCCAGGTCCTCCAAGACGAAGGAGACCGCCACCGCGTCCTCCTACGCCTGGAGGTCATCGTCCGGTCCCCTCTCCCGTGGCTACCCCCCAGCAGCCCCAGATCCTTGGATGATCCCCAAATGGGGCCTGGCGTGCGTTTGGGCTGGAGGCCTTTTCCCCCTAACCCTTGTCCTCCAAGAGGCCCATCACCCCCGCCAGGGCTTCCGCCAGCGAAACCACCCAGAGCCCCCTCACCCTCCTCCCCATGAGGTGTCCAAAGTGGCGCCGGTCCCCGGTCACCAGGGCCTCGGCGCCGGCCTTCCAGGCAGCCGCCAGGATCGGGGCATCCTTAAGGGGTAGGCCTTCTGCCAGCGCTTTCCGCACCAACGCCATAGGGGCCTCGGGGACCGTCTGCACCCGTTCCCGTATCCGCTGAAGGCACTCCAGGGCCTCGGGCCGCTTGGCCTCCAGGTTGCGCCGGGCCTCCTCCAGGGCGTGGGGAGAGGTGAGGAGGAGGACCTTGGCCCTCGGCGCCAGCTCCAAAAGGGCCTGCGCTCTCCCCTCTTGCCAGCAAGCAGCGAAGAGGACGTTGGCGTCCAGGAAGAGGCGGTGGAGCCTAACGGGCGAGGGCGGCAAGGCGGGCGCGCTCCTCCTCGGTGAGGGTGTCCTCGGCCAGGAGTTCCTGGAGGCGCTCTTCCGTGTAGACCTCTAAGGGGTAGACCCCGGCGGGGCGCAGGAGAAGGCCTCCCTCGGGAGCGAGTTCCACCAGGAAGTAGGCCTCCCCCTCTACGCCCAAGGCCTTGAGGAGGCGCTTAGGGATGGAGAGTTGGCCCTTGCGGCTGAGTTTGGCCAGCTCCATGATTTCAGTATACCAAAAAGTTGGGTTTTTTTGTTTCCCGCCTCTAGGCCCTAAGAATCCTGGAGGAGCCCTTGGCGCTAAATGATACCTTCGTGTGCTACCTCATAGCTCCACCCCGGCCATCCTGAGAAGCACCCGGCTACGTATGAGGTTGTGAACAAGCAGGATGAGGTTCACCCGGGCCACCAGCCCCCAGTAGGACCGGGCCTCTATCCGATGAAGCCCCAAAGACCGCACCATCACGCTGAAGCGGGTCTCTATCCAGTTCCGTACCCTTCCCATCCACCCTCTCCACCCCGTCTCCACCACCCTTCCTCCCCTGACCCGATAGGGTGGTGCCTTGACTCCCTGGACCCAACGAAAGCCCCGGTCCCCGAGGACCGCGGGCAGACCGTCCAGCAGGTCCCTCCCCCAGGTCTCCCGGGCATTACCGGGGAGAATGGCCCAACGAAAGAAGAGACCCCGCTCGTTCATCACTGGCATGATGCTTTCCCGTCAGGGAAACAGCTTGTGGAACCACGGGTTGGGAGGGCGTGGGTTCCGTCCTACCGGGCTGGGTAGCCGAGCCCCCGCCCAGGGCCTCGGAGCCCGAGGTCATGGTGGGAGCGCAAGCCCCCAAAGCCAGCAAGAGGGCCAACAAGAGGGAAGACCGCCACATTCGTCCACTTTTTCCAAGCATCATACCTATTCCATAGTAGCACAGGTTGCCACGCCTGGGCCCAAGAGGTCGTGTCAAGAGTTATGTGTAGTTATCCCCCCTTTCGGATATTCAATGCATACCCCCTTGACAAGCCAAAGGAAAAGGGGGCGCTTGGTGAGCTGTGGAAGCACACCAGACGCCCCCTTCCATCCTACCCCTGCCCCTGGAGGAACTGGTCCCCCTGCTCCAGGCATGGCTCCAAGCCCGCTTGCCAGAAGGGGAGAGAAAACCCGGCAGGCCCAGGACCTTCTCCGACCTCAGCCTCTTTCTCTTCCACCTGGTCCGCGCCCTCCTGGGCTTCTCCAGCGAACGCATGCGCCGGGAACTGGCCCGCAACCCTAGGCTCCGCAAGCGCCTCGGTCTAGAGCGCGTTCCCTCCTCTGCCACCCTCAGCGAGCGGAGCCGGAAGCTACCCTGGCCCCTCCTGCGGGGAGGGAAGCGGGTGGGCCGGGGGAGGCGGGTGCTGACCATGGGGGTAAGATCGTTTAAGAGTCGCTCTTCAACGATCCCACCCCTTTACGACAGGCTCTTAACCCTCCACAACGCCATCCTCTTCATCGCGATTTCCCCCCTACACCAGGGGTCCCGGACGCTGCAGGTACCGCTTCACCGCATCTGCGGCCCAGAAGGCCAAGGCGCCCACGGTGCCCGTGGGATTGTATCCTGCGTTTTGGGGGAAGGCGCTCGCACCCACTACGAAAACATTGGGCACATCCCAGCTTTGGAGATACTTGTTGACAACACTGGTGCTGGGGTCGCTCCCCATGACAGCTCCTCCTGTGTTGTGAGTACTTTGGTAAGGAACGATGCTGTAGTGCTCGCTCAACCGGTTGATCACGTAGGTCTTGGGACCAATGGCCCGGGCGATACGCTCCAGAACCTGGGCGGCAAACTGGGAGGCGCGATGCTCGTTGGGGCCCCAGTCAAAGGTCATCCGCAAAAGAGGAAGGCCAAAGGCGTCCTTGTAGGTCGGGTCCAGATCCAAGTAGTTTGTCCGGTAGGGCAGCACTCCCCCCTGGAAACTGATGGAGAAGTTCCGCTGGTAGTAGCGGGCCACGGCCTTTTTCCACTCCGCCCCCCAGCGCGGAGTCCCAGGAGGCACTCGCAGGGATTGGATCGGCCGCGCGCCCGTGGTGGAGCAGGCGATATTGCCCCCTCCGATGAATCCCAGGCCCCCATGGTCAAAGTTGTCCCCGTTGAAGTCGTCGATAGAAACACCCAAGGCACCAGCCCCCATGAAGGGGTTGAACACCTTGTCCTCGAAGAAGAGAACGACTGAGGTGAAGGCCTGGTATGCGTAGTTGCGCCCCACCACCCCTTGGCCGGTTACCGGGTCATAGGGTTTGCCAATACCGGAAAGGAGTAGAAGGCGTACATTGTTGAGGACATAAGAGGTGAGGCAGATGACTTCAGCGGGCTGCTCGTACTCCTCCCCTGTTTTCAGGTCCACATAGCTTACGCTTACCGCCTGTCTCTTGTCAGGGCTTAGGTTGATCCGGGTGACATAGGCTTCTGTGCGTAGCTCGAAGTTCCCCGTGCGGAAGGCCACCGGGAGGACGGTAGTCTGAGGGCTGGCCTTGGCGTTGACCTCGCACCCAAAGCGTTCGCAATAACCGCAATAGACACAAGCTCCGAGCTGCACGCCATCGGGATTGGTGTAGGGTTGGGTCACGTTGGCCGAGGGCTGAGGGAAGGGGTGGTACCCAAGCTCCTGAGCTGCCTGGCGGAAGAGGTGGCCCGCATAGCTGGTCTTCATGGGGGGATTGGGGTATTCCCGGTTTCTTGGTCCTTCAAAGGGATTGCCCCCGGGCTGGATTACCCCCTTGAGGTTGCCTGCCTTGCCGGCAATGCCGCAGGTGTACTCAAACTTGTCGTAGTAAGGCTCCAGCTCTTCGTAGGTGATACCCCAGTCCTGGATCGTGCTCCCTTCGGGAATGGCGCTCGGGCCGTAGCGCTCGAGGGTCTTGGTGCGCATCTCGAAGTCGTAGGGTAGAAATCGCCAAGTGACTCCATTCCAGTGCACCCCTGCTCCCCCAAGCCCTTCTCCGGGCAGGAAAGAGCCCAGCACCCGCATAGGCCTGGCCGTTTGGTTGCGGTTATTACGGAAAGTGATCGTCTCTCGAGAAAGGTCTTGCATGAGTTCATAGCGCACCGCGTAACGCAGTTCATCGTGGATCCACGGGAGCTGGAAATCTGGGATAGTGTCGCGGTAGTGGCCGCGCTCCAGACCCACCACCCTGTATCCCGCTTGAGCAAGCTCCTTGGCGAGGATGCCTCCCGTCCAGCCTACGCCCACCAAAACCACATCCACGGGCTTTAAGCGCTTGGCCATGGTTCACCTCCTCTTGGCCAGGGGGCGGTGAATAGGGTGACCATGCTCGTCCAGATCCACCACGCCCCCGGCCACATCGGCGATGCCCACGGGTTCCACCTCGTAGGGCTGGTTGAAGTTCTCGATAAAGCTTACGTAAGCTGCAGCCACACCCGGGAAACCCACGAGGCGCCAGCCCACCTTGTTTCGGTTACCACCGTATACCGGATCCGAAAAATAGCCTTCTACGGTGTTTCCCAGAAGCATGTTGAAGAAGGTTTGGGCCGGAGGTCCTCCTAGGCTCACGAGATCAATGCGCCCGGCCTCGAGGCCACGGAGCACCTCGTCCTGTTGCTCCGGATTCAGCTGGGCAAAAGAATGGCCGTAGGTGAGCTGGCAGTAGCGGTTTACGGCGGCAATGCCGGTTCGGTAAACCTCCCTTGGTGTTAAGGGGAGTTGGTAACCCTGTTGCGGCGTGCTCTCGCCCCAAGGGCCGCCCATGTACCACTTGGCAGCAGCGCCGTAGGCCCCTGCCAGCTGCTGGTCGATGAAGTAGGCGCAACCGGCTTCCCGACCCCCGGGCCCAAGCTCGTCCGCCGGAATCAGGCGGTCCACGGCGGCCTCCACGAAGGCCGCTTCCTCAGGGCTGAAGAAATTGTAGGCCTCTGGGCGCACGGGTAGCGCCTGGGGCTTCTGAGGGCTCACCTGGGCTGGGGCCGCCTGGGCCTCATGAGGGTGCCCCTTAGCTTGGGCTTGGGCCCCCGGCGTCAGAACCGTAAAGCCTGCCGCCGCTCCCACAAGCTTGAAGAATCTTCTACGGTTCATACGCCCTCCCGAGGAGCTTAGCTCAAGGTTAGTAAAGCTGTTAAACTTTGTCAAGTAAGAGAAAACAAAGTATGAACCGGGTTCATGTATCTTGCCCCCTGAGGGAGGCCCTACCGCCCCGGTTGCCGGGCCGCCACGCCCGCGGGATTGATGGGTAGCCACCCGCCCTGGCCTCCCCGCCGCACAGTATCCCGGTCGTGAAAGACCGCATCCACACGTCCTGATGGCCCTGCCCGACGTAGGACCCCAGGTGGCGGCAGCGGTGCTGGCCCTCCTCCCGCCCCACCTCTGGGGCCGGGCGAAGGCGGCAGCCTCCTACACGGGGCTGATCCCCGAGCGGGAAGCGTCGGGAAAGAGCGTGGAGAGGAGTCGGCTCTCCAGAAAAGGGCCTCCCCTCTTGCGGTGAAAGCTCTACATGGGGGCCCTGGTGGCGGTGCGCCATGACCCAGAGATGCGGGCCTTCTACCACCGTTTGCTCTCCCGAGGGAAGAGAAAAAAACAGGCGCTTTTAGCCGTGGCCCACAAGCTCCTCGGGCGGATGATGGGGCGGCTCAGGGAGTACTACGCGACCCAGCCGCACCAAGGGGCCGCTTGACAGGCAAGACAGTATCAACCCTATTGACTAGGGGCAATATTGCACCCGTTAACCCTTCCATAATGCCCCGGTTTCCCACACAGCTCTATCGTTTGGCACCACTTCCCTCCCCACGAGCTTGGGCAAGAGAACCCGAGTTGCCCGCTCCCTGGCCTCCCACCAGCTCCCTCCCCCCTTTCATCTCCGGGAAAAAGCCCTCTAACGTGAACCGCCTCCTCCTCCACCACAAGCAGGATCCAGGGCGTGGCAGGCGGGAAAAGCGGTTGACCTATGTACACGCCAAAACCTCCATAGGGCATAACCCCAAGGGACTTCCGCGCCTTCCTCCCCCTGCACCCCAGAGGGCAAGCGCCCAAAGGGTGAGCAGGTCCAGCCCCGCCCGGAAGAGGCTCTGTCCCAGCCTCCCGTGCTTCTTGGGCCTCACCGGACGCACCCGGTGCAGCACAAGCCCCGTCCGAAACGCCCACACGAAGGCCAGGCTCAAGGGGACCAAAAGCCGCGAAAGCCTCTCCCCCCGCGTCACGTGCGTGGCCTCCAGGTCAAATCCCCGCCCCTTCAGGGCCCCAAAGAGCCGCTCTATCCCCCACCTGAGCCCGTACACCTCCAGCACCCGGTGAGGGTCCAGGTCCGTAGCCACAATCAGCCACTCCCGGACCCCAAGGCGCAACCCCACCACCCACATGCGCCGCCCGTAGACCCAGTACCGCCGCCTGGGCACCCGGCTCTCTCCCACCTTCAGGGAGGCAAAGAGCTCCCAGGCCCGAGGGCCCGAGCCCAACCGCCACATCCGGGTGTTGGCCTTGATTCGGATGCACCGGGGGATGCCCTTCTCCTCCAGGTACCGGAACCACGCCTCCCCTATGAACTCCCGATCCGCCAGGAACCCCTCCACCCGGAGGTGGGGGAAGTGGGCCCTCAGGAAAGCCAAGGCCCTCTCCATCAGGGCGATGCGTTCGGGGGTGGAGGAGTTGCCATCGTGGGGAAGGAAGCTCCAGAACAGGGGGACGGCCAGGCCTTGGTACAGGAAGGCCAGCATCAGGAGGTTGACCTTGCTCTTCCCCAGCTCCCACTCGGTCCGGTCCATAACCAGGAGGAGCCCTTGGGGTCGGAGGAGGGCGAAGATGAAGCGGGCATAGCCCTCCCCGTCCAGCCCCGGCCAGGCCAAGAACCGCTGGAACCTTCGGTAGGCGGAGCGGGGGTCAGGGCTGGCTATGGAGCCGAGGGAAAGAGCGAGTCTGGGGCCGCTTGTGGTGCGGGCGGTGACCAGAGCCATCACCAGGGCGGCCAGGAAGGTGAGGCGCCTGAGGTCGGCCTTCCAGTATCGCTTCAAGGCGTTGATGAGTGGGGTAAGCTGTTCCATGGGGACCACCTCCTATGGGTACCTGCCCATCCACGTGGGCGCAGGTCCATCCTAAAGGGGTGGTCCCACGTTTTGACGTGTACTGAGGCGGTTGACTCAAAACTTGCACTTATTCACCGCGGGCATGAGTATGCTTGGGGACCACTTGAAGAGGGCTACTGGTTTCCCCTCTTATGAGGGGTGCCATGAGACCAGTAGCCCTATCCCTACTTTGGACCATCCTGGCCCTCATGCCAACCCCCCACCTGCGGGAATCCTTGAAGGCCCTGTTGTTCCTTTTCCTCACCGGCCACGGCAAGGCTAGACCCCAGCACAGCAAGACCAAGTCCCCCTCCGCCCTCTCCCGCTTCCTCAACCGCTACCCCTGGCCCACCCGCGCCCTCATCCGCCTGGCCCGCGAGGAGGCCCAGAAAGCCCTGGACCGGGCCAGGCGGAGAAAGGGCCCCAAGCCCCGCCTCCTGGTGGTCCTGGACCTGGTCACCCTGGAAAAGCGGGGCCACTTCCCCCACCTCCCCCTCTCCTTCTTTCACGGCAAGTGGGGCCTCCACCTCGTGGTCCTTTACCTCGTCTACGGGGACCTCCGCGTCCCCTGGGCCTACCGTCTATGGCGGGGCAAGGGGGAGAAAGGCCTCTCCCTCCTGGCCCTGAGCCTCCTGGCCTCTCTGCCCCTCTGGATGCGCCGGACCTTCCGGATACGGGTGGCCGCGGACGCGGCCTTTGGTACGGCCTGGTTCCTCTTTGGGGTGAGGCGGTTGGGCTTGGAAACGGTGGTGGGGATGCGGCGGGACCGGAGGCTGCGGGGAGGGGGAAGGCTTTTGGACCTCAGGCGGCAGGGGAGCCGGGTCTACCTGTGGGGGCTTTCCTTCCCGGTCTGGGTGGCCTGGTACCGCTACCCCCTGCCCCAAGGGGGCTGGGAGTGGCGGTACGTGGTGGCCACCTTTCCCGCCACGCCCCGGACCATGCTCACCTGGGGAAGGAGGCGGTTCACGGTAGAGCACTTCTTCCGGGCTGCGAAGAGTGAGTTCTCCCTGGGGCAGTTCGGGCAGCGGACGGCCTTGGGGGTGCACCGCTTTCTGGTGCTCTCCCTTCTGGCCTACCTGCTGGCCCACTGGGTGGGGGTGGAGGGGAAGGGGAGCTGGCGGGAGGCCAGGGAGGGGGCGGCTCGGGTTCTCTTGCCCGAGCTGGTGGTGCAGGTCATCCTGCGGGAGCTCCACGCCCTGGGTCTGGGGCCGCCCGGGGGAGGGAGTGAAGGTTTATGCGGGGTATGCGGGAGGTGCAGGTTTTGAGTATAGTGATTTCAAATGCTTTCGCCCTTTGGAGGCGAGGAAGAGACAAAAGCAATCCCCCTCGAAGAGGAAATCCTTCTCGCCTGGCGCGTCTTTTCCGCCGCCTTGCCGCCCAACTTTCTCGCCCCCGTGAGCGCTTCCCTACACACCCTGGTGAGAGAGGCGGAGGGCAAGGAAGGGGCCGAGCTCGAGGCGTACGCGTGGGAGCGTCTGGAAGAGCTCGCCCGGACCTCGGTCGTCAAGGACGCGATCCAGAGCTTTTTGGAGGTGGCGGCGGAGAAGCCCGAGGTCCTCCGGGCGGGGCTTTTGTGGTTCAGGACGTGGAATCGCCTCTCCCCGGAGGAGCGGGAAGCCCTTTACAGGAAGGCCGAACGGTTCAAGCCCACGGCGGAGCTCGCTTCCAAGGCCTCCTTTCTCCAGGGCCCTCCTCCGCCCCCTAAGCCCCTTTCCCCTTCCGTTCAAGCCGCCCGTTCTTCCCCGCCCCGCTTCACTCCCACGCCCGAGCAGGAGGAGGCCGTGCGGGCGTTCCTCTCCCGCGAGGACATGAAGCTCGTGGCCGTGGCGGGGAGCGGCAAGACCACCACTTTGCGCCTCATGGCCCAGAGCGCTCCTAAAGAGCGCCTTCTCTACGTGGCCTTCAACCGTTCCGTGCGCGACGAGGCGGAGCGCACCTTCCCCGGGAACGTGGAGGTCCTCACCCTTCACGGCCTGGCCCACCGCCACGTGGTGAGGGGAAGCGGGGCCTACCAGAGGAAGCTCGCGGCGAGGAACGGTCGCGTCACCCCGGGGGACGTCCTCGAGGCCCTGGAGCTTCCCAGGGAACGCTACGCCCTCGCCTACGTGATCCGGAGCACCTTGGAGGCCTTTCTCCGCTCGGCCTCGGAGGTGCCCACTCCCGCTCACATCCCCCCGGAGTACCGGGAGGTCCTCCAGCGCCGCGACAAGGACCCCTTCTCGGAGAGGTACGTCCTCAAGGCGGTGAGGCTCATCTGGAAGCTGATGCAGGACCCCGACGACTCCTTTCCCCTCTCCTTCGACGGCTTCGTCAAGATCTGGGCCCAGGCGGGGGCCAAGATCCGGGGGTACGACGCGGTCTTGGTGGACGAGGCCCAAGACCTCTCCCCCGTCTTCCTGCAGGTCCTCGAGGCCCACCGGGGGGAGCTCCGCCGGGTCTACGTGGGGGACCCGCGCCAGCAGATCTACGGCTGGCGCGGGGCGGTGAACGCCATGGACAAGCTGGACGCCCCGGAGAGGAAGCTCACCTGGAGCTTCCGCTTCGGCGAGGACCTCGCTCGGGGAGTGAGGCGGTTCCTGGCCCACGTGGGCTCCCCCATCGAGCTTCACGGCAAGGCCCCTTGGGACACGGAGGTCTCTCTGGCCCGCCCCGAACCCCCTTACACCGCCCTCTGCAGGACGAACGCGGGGGCGGTGGAGGCCGTCACCAGCTTCCTCCTCGAGGAGGGGCGGGAGGGCGCGAGGGTCTTCGTGGTCGGCGGCGTGGATGAGATCGCATGGCTTCTTCGGGACGCTCACCTTCTCAAGGTGGGGGGCGAGCGGGAAAAGCCTCACCCGGAGCTCGCCCTGGTGGAGAACTGGGAGGAGCTCGAGGAGCTCGCCAAGGAAGTCAACCACCCCCAGGCCCGGATGCTCGTCCGGCTCGCGCGCAGGTACGACCTCCTGGAGCTCGCTAGGCTTCTGAAGCACGCTCAGGCCGACGAAGAGGGGAAGGCGGACCTCGTGGTCTCCACCCTCCACAAGGCCAAGGGGAGAGAGTGGGACCGGGTGGTGCTCTGGGGGGACTTCATCCCCGTGTGGGACGAGAAGGTCCGGGAGTTCTACCGCAAGCAGGGGGCCTTGGACGAGCTCAAGGAGGAGGAGAATGTTGTCTACGTGGCCCTCACGCGGGCGCGGAGGTTCCTCGGGCTCGACCAGCTGCCGGACCTCCACGAGCGCTTCTTCCAGGGCGAAGGGCTCGTGAAGCCCCCTTCGGTCTCCCCGCTTTCGGTGGGCGGGGCGGGCGTGAGCGCTGACCTTCTGCGGGAGTTGGAGGTGAGGGTGCTCGCCAAGCTCGAGGACCGCTTGAAGGAGGTGGCAGAGGTCCTGGCGGCCCTCCTCGTGGAGGAGGCCTCTAAAGCAGTAGCAGAGGCCATGCGGGAGATGGGGCTCCTCGGAGAGGAGGGTTAGCCTTTCCCCTCGCTCTATGTGCACGCTCTTAGTGCCCGTCGAAACGTAGGGCCCCTCCCTTGGGGTGTGGGGGAAAGGCGCGGAGATTTTGACACACACAAAGTCTCCCACTCCGGAGCTGCCGCCGAGACCTCACCTCCGGGAATCCTTCAAGGCCCTGCTCTTTCTCCTCCACGGCCCCAGCAAGGCCAGACCCAGCACGGCCGGACCAAGTCTACCCTGCCCCCTCCTGTTCGCCGAACCGCTACCCTCGGTTCATCCGGGCCATACAAGAAAAGTGCGCAAGGAAAGCCCGGGATCAGGAAGAACCGGAGGGAGGCGAACATCGAGGCCGCCCCCCTCCTCCGGCCTTCCAGCCCCTTGAAGCCTCTTACACGCGAAGAAAGGCCTACCGTGCCGTGGCTACCCTCCCAGGATCCAGCGGAGAATCCTCCAGAGAAGCCCTTTGGGCTTGGCCCGGGAAGGCTCGGGCTTGGAGGCCTGGATCCCGGGGACGATGGGCCCGCCCTTTCTCGCCCACTCCAGAGCTTCCTTAGCCCTGGCGTCCACCCACCTCATCTCCGGGGTGCTGCACCGGGGTTTGTGGCGGAAGGTGACCCTCAGGAGCCCCCTGAGCCTGGCCACGCCTTCCAGCGCCCGGTTCAGGTCCTGCCGCCCGTTGCGCTTCCCGTTTTGGAGGTGCTCCACCACGGACTCGTTGTCGCAGAAGAGGGTGACCTGGGTCCCGGGGCCCAGGGTCACGAGGACCACCTCCAGGGCCAGCTTGACCGCCATGACCTCCGCCAGGGTGGAGTCCTCCACGGGGAGGGAGAGGGAGGCGGAAAACCTTCCCCCGCCCTTGGCCTGCACGAGCCCGAGAACCGCCAGACCACCAACGCCCCTCTCGGTGTCCACCGAAGCGTCCGTGTACACCACTACCGGCTTGCTCACCTTCTTTCCTCCTTTCTCCTGCCGGCGAAAGAACGAGGCGGCCGGTTTCCCGGCCGCCCCTCTCGCCCAAGTTCTTCGCCTACTCGCCCTCGGCCAAGCCCAGGAAGGCCTCCAGGGCCACCAGCTCGTAGAGGTCGTCGCTCTCCTCCAGGGACTGGGTGAGGCCAAAGGCGGCGAGATCGTTGGGGCCAAACCGCCTCTTCAAGGCCCGCTTGCGGCGCTTCAGCGCCTCCCGGACCAGGGCGGGGGCCCACGGGGGGAGGTCCAGGTCGGGATCGTGGAGGGCCTCGAGGTGGTCCCAAAGGGCGGTGCACACTAGGAGAAGCGGGGCCAGCGCGGGGTGCTTCTCCCAAAGGCTCCTCTCCAGGAAGCGCCGGAAGGCCTTCATCTCCTCGTAGACCTGGCTGGGGAAGTCCAGGGCGTAGAGCTCAAGCCACCCCTCCACCACCCGCCTCAGGTCGCCTTTGGTGAGCGGCACCAGCCTGGGTTCGGAGGCAGCGTCCTCCCGCACCCGAAGCTTCAAGAGGGGTTCGTCCTCCGCGAGGGGGAGGAGGCCAAGCAGGAGGCGGAGGAGGTGGAGCTTCACCCTAACCCGGCCCTCCAGAAACATCCCGGCCTCCTGTTCCAGCTCCTGGAGGGCTTCCGTCAGGCTCCACCCGTAGGCGAGGGGCGCCTCCGCAAGGGCCTCCAGAACCTCCTCGGGAAGCTCCGGCCCCGGGAGGAGGTCCACCTCGGCCTCCGCCTCCGAGGCCTCCCCGGGCTCGGGGTCCTGGTTCAGCACCCCGTCCGCCCAGTCCAACCAGTAGCGGTACTCCTCCAGAGCCTCCCGGTCCTCCCAGTCGAGGTCTTCTTCGATCTCCCAACCCATGTCGTCGTCCCAGAGCATGCTTTTCCTCCTTTCCGTTGAGAAGGCCGCCCGGCCTTCGGCCGGGCTAACCGCTTCCCCCTAGGCCCGTTCCAAAGGGGGCTTGGGGGGGTACCCCCCCTCATCAACCTCCAGGGGCCGTTAGGCCCACCCTTTTACTTCTCACTTCATTCCCTTTTCACTCCTTGGTCTGGGGCGGCCCTTCTGGGCCGCCCCGTGTTTTCTTAGCTTTTTATGGGGTGTGGGGGAAAACGAAAAAACCCCGCTCAGAACAGGATTTTCACGCGTTTTTCGCTTGAATTATGAAAGGGAGAAGAAACCTACCCTTTCTTAAAGAAGAGCCCTTCACCCTGGCTCAAGAGCTTCTCCCGAGACTTCCACAAACTGATGTTGCCCCGGGCCCTAGACTCGGGAAGCCCGAGCTCGTCCGTGAGGTAGCGGAAAAGCTCCTCCTCCGAGAAAATCCGCCCGCCGAAGCGTTCCCGAGCCCTCTCGATGTACGACTCCCTGGACCTCTTGGAGGCCCTTTTAACCCCCTTGGCGCTTGAGGAGCTGGCCCGGCGAAGCCCCCTCACCCGCACCCGCAAGACCTCCTCCACCTCCCGCCAAACGTCGCCCCGGCCCCTCTCGTAGAGGAGGAGGCCCCAGTCCTCCTCCCCCTCCCGCCTGGGCTCGAGGCGGAAGATGTGGTCGGCGTTGGCGGCGATGGCCCCGGAGCCCCGGGGACCGCTGTTGCCCTTGGTGGCGTGGTGGATGACCACAAGGCCCACCAAAGGCTCCCTCTCCGACGGCGAGATGGCCCGCTTGAGCCGGGCCATGACCTCGTCCATGGCCTTGGCCTCGTTCTCGCTCTGTTGGGGAGGAACCAGCTTGATAAGGGAGTCCACCACGACCAATGCAGGGGCCTTCTTCTCTTCGGCCAGACGCTGAATGGCCTGCAGGGCGCGCTCCAGCTCCCCCACGTCGTTGAAGGGAAGGATGTGCTCGGTGAGGCCCTCGGCCCCCAGGGTTTGGGCGTACTTCCTCAGGTGGGCGTACCGGGTCTCCGTGGCGTGGTAGAGGTAGAAGCGCAGGTCCAGGGGTGCCCTCACGCGCCAGGACCTGGAGCGCACCGCATCGCCCCCGTCCTCGCTCGGGGAATCCGGCGCGGCCCTCTCCCCATCGGGCCAGCCCAAGAGGGCCACCGCCGCCCGGCTCTTGCCCACCTTGGCCTCGCCGTAGAGGAGGGCCACCTCCCCGGCAAGAAGGACGCCGCTCAAGGCCCCCCCTTGCCAGACCTGTAAGATCGGCCTGGCGCCCTCCTCTTTGTCGCGCCGGCTCTTTAGTCTTCGGAGAAAAGAGCGGGCTTCCTCAAGGGTCATCCCGCCAGACGCCTTCGCCGCGGACAACTCGGAGGTGGATCCCATCTTGGAACCCCATGATATCCCGGGGAAAAGAGGCAGGCATTTAGACTGTAACCGTTATGAAGCCGAATGGGTCACCCCAGAACCCCTCCCCTGTGACCCCAGATCAGCTCCTCAAGAATCTCCAGTCCCTCCTGACCAGAGAAGTCTTCCGCCGCCTTCGGGAGGAAGGGCCCTACCTGGTTCAGGGCACCTTTGCCAACCATTCCCAGAAGGCATGGGGGAACTTTTACTACGGCGACTTCAAGGGAGGATCCACTTCCATCCGCCGCAAGGTTCCCCTAGGGATCACCCTCAGGGAGGGAAGGAGTTATACCCTTTTATGCTAATTCCTTCGTCCTAGGCCACCAGTGGAACAGGGTGTGCCGCCTGAGGGTCTCGGGGTCCTGGGCAAGGACCCGGCACCGCTCAGCCACCGCCTCCATCATCTCCTCAAGGTCCCGGAAGTACCGGTTGGCCACCGCCTCGTTCACCAAGGGCCACACCCGTTCCACCGGCTGCAGCTCCGGGCTGTAGGGCGGCAGGAAGACCAGCCGCACCCCCTCTGGCACCTCCACCCGCCCCGACACGTGCCACCCCGCCCGGTCCAAGACCACCCACGCCTCCTCCCCCTCCCCAAGCCAGGCCCGAAGCTCCCGCAAAACCCAGCCCATCACCTCCGTGTCTATCCCGTCCACCAAAAGGCTCAGGCTCTCCCCCGTCTCCGGCTCCACAAAGGTGCACACATAAAACCACCGGTACCGGTGCGCCCCCACCGCCAAGGGCCTCTCCCCCCGCCTGGCCCACACCCGCCGGTACACCGGCTTGAGCCCCAAACGGTGTTCGTCATACGCCAGAAGCCTCAC

Protein sequences of DBSCAN-SWA_2

>NC_017273|89674:150987|134817_135138_-|WP_014630458.1|DBSCAN-SWA
MFVTMNRIPVRPEYAEQFEEAFRQRARLVDRMPGFIRNLVLRPKDPGDPYVVMTLWESEEAFRAWTESPAFKEGHARSGTLPKEAFLGPSRLEAFEVVLDSEGQDA
>NC_017273|89674:150987|127134_127929_+|WP_014511105.1|DBSCAN-SWA
MPQAVVLELVGEKPPLYPGRYAHGLFFALLSRVSPELAQKLHEAPRKPFTLAPLPRVGPEGATLKGILRLRLTALDDGLFAPFLRALLEAAPDGLPLGDSSYRLARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTRYTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNLRFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKTPYGMGLAVPL
>NC_017273|89674:150987|118798_119383_-|WP_041444555.1|DBSCAN-SWA
MGHGGAVEYLPLSKVNTVVYCPRRFYLEYVLGEAHANHHLIEGHYLHERAYTEPGEESGLWVWSDRLGLLGVVDRLEWRRGEACPVEYKLGRAKEEAYLSDAVQLAAQALCLRESRGIEARRGFVYYHKSHTRREVVFTLELFRAVEAAVVRMRALLRSPRPPRVEVPPSKCEGCSVRGACQPELWRKGVAGWA
>NC_017273|89674:150987|132852_133329_-|WP_014511111.1|DBSCAN-SWA
MPSSRTSDAEPLFLDTSVLVRLYYLEPEDPFEWAVDLAQRPGTLLAASHLAYVETLATFHALRRGRAITSRRQASLSAAFRADWPAFLRVPLSPPVVQLAGALAEEHPLRGADALQLASFAWLWEKEGKGRFFTLDRRLYLVARDLVPTVPVPAFEEV
>NC_017273|89674:150987|110221_110692_-|WP_014511091.1|DBSCAN-SWA
MVRSWDVTYPCYIEHDPESGTYGGFCVDLPVFVAGKASVEEARKALEEGVAYYLAHLEVEERPFPRPGATPPPDLEEERDRLIPVEIRPSPVNPVSLAIEKALRRKGLKRKDLAERMGVPPSVVTRILDPLYFGHTLSTLRRVAEALEKDLVVAFR
>NC_017273|89674:150987|137440_137683_-|WP_008633599.1|DBSCAN-SWA
MELAKLSRKGQLSIPKRLLKALGVEGEAYFLVELAPEGGLLLRPAGVYPLEVYTEERLQELLAEDTLTEEERARLAALAR
>NC_017273|89674:150987|96535_97618_+|WP_014511085.1|DBSCAN-SWA
MRPLLSQMALEVQVPLRVANPSGLVRSPAFSVDGGPFAPLRQTRYIRGEPVETVLLDSVESQANRQEALLYRHLPLPDVQVELFDGRRVSQYEAPGRILDAIFREATLGGQPSHQTPLFQAIARGGEEAERALFRHSPLTLVYGGWLSYGDISPEVAPKWPRLVALEILGLEPREAHRTSSRLDPLGVPGELPLPEAMSQALKEQGKKGRLSEAGLGRIPPTASPMDVAVRGAVLVGAVSLVGLRNLRLPQEAKEVLLALALLGLALQHKEGYRLRSGADLVPEEGGCLRVRALPSGEEVCLEVEPLREELDRLLGELPEELRWPGEPVVLQANETLNQLYRNALLGKAERAKAKREKEG
>NC_017273|89674:150987|137004_137460_-|WP_014511107.1|DBSCAN-SWA
MPPSPVRLHRLFLDANVLFAACWQEGRAQALLELAPRAKVLLLTSPHALEEARRNLEAKRPEALECLQRIRERVQTVPEAPMALVRKALAEGLPLKDAPILAAAWKAGAEALVTGDRRHFGHLMGRRVRGLWVVSLAEALAGVMGLLEDKG
>NC_017273|89674:150987|130552_131008_+|WP_014511107.1|DBSCAN-SWA
MPPSPVRLHRLFLDANVLFAACWQEGRAQALLELAPRAKVLLLTSPHALEEARRNLEAKRPEALECLQRIRERVQTVPEAPMALVRKALAEGLPLKDAPILAAAWKAGAEALVTGDRRHFGHLMGRRVRGLWVVSLAEALAGVMGLLEDKG
>NC_017273|89674:150987|115345_115525_+|WP_081466172.1|DBSCAN-SWA
MGRVRNWIETSFSVMVRSSGLHRIEARSYWGLVARVNLILLVHNLIRSRVLLRMAGVEL
>NC_017273|89674:150987|111135_111687_+|WP_014511093.1|transposase|DBSCAN-SWA
MRLTKHQRRPRLELKLRPHPDNLGHRLGLKPVYRRVWAPRGKTPLAWVRPRYRWLYVYGFARPSTGESEFWLLPPVNAAAFSEVLRQFARLRGSGERKLLLVILDRAGWHVSGRVEVPEGVGLVFLPPYSPELQPVERVWPLVNEAVAERCLVLAQDPETLRRRTLFHWWPRTKASAYTPSYS
>NC_017273|89674:150987|123800_124715_+|WP_081466160.1|DBSCAN-SWA
MPPKEERFSSATGGGRPWRRFGGWPRLLWRRTFRLWLPLPNMYAIALRIRPTSALTFRVLPGSILDIATYPFVPPTTLSGWLRRLFWAQEGLLPPDQREGNTPRFYVLPRRYLPLGAYPVGEWRVHRTHRHGPRAFTHSEFSRLRREGKPPKGGDLQLHTWEYLLAEEFLGAVLAEKEEDLRRLQGLVGYGAKLGKEGFAYLEAVGEPLEVRLEEGDAPFTPVRAEAWGGAIQGAYPLYRFRFGEAEDPDPASPDPSPVIGYEGAYFVLPRGRGLAKGFSLEGRFFAWDLVEFLWARASGGSSS
>NC_017273|89674:150987|113211_114177_-|WP_014511096.1|DBSCAN-SWA
MREGLGLEVWDHPEERRRVVGEALERWDEGVLKEALWAYLVRHRKKPDRAAPHYVGYFVRWLALKGRRWPHLEPEDPKAFLLEAKERGFPGGERGPLSWGTVERARASLRHLFPFLDWAGHPMPSHVRLPSRQELPVVAPSRAMPEEAYQDLLEKAGAYPLAYWRPLLRVLLVLLGEVGLTVKEVADLWKEDVREKSLLVRGTKLREVPLSPLAREVLADWLPQRAFLASHQPLPYPHLLLKPAPGKNRGKPLGLGEAKWILTEFADFAGVKAEGKRRADLALPLRWRAIRRFLKEGHPREKVAYWTGMKSLVVPGWGEEG
>NC_017273|89674:150987|143659_144760_+|WP_041445142.1|transposase|DBSCAN-SWA
MRPVALSLLWTILALMPTPHLRESLKALLFLFLTGHGKARPQHSKTKSPSALSRFLNRYPWPTRALIRLAREEAQKALDRARRRKGPKPRLLVVLDLVTLEKRGHFPHLPLSFFHGKWGLHLVVLYLVYGDLRVPWAYRLWRGKGEKGLSLLALSLLASLPLWMRRTFRIRVAADAAFGTAWFLFGVRRLGLETVVGMRRDRRLRGGGRLLDLRRQGSRVYLWGLSFPVWVAWYRYPLPQGGWEWRYVVATFPATPRTMLTWGRRRFTVEHFFRAAKSEFSLGQFGQRTALGVHRFLVLSLLAYLLAHWVGVEGKGSWREAREGAARVLLPELVVQVILRELHALGLGPPGGGSEGLCGVCGRCRF
>NC_017273|89674:150987|120738_123039_+|WP_014511101.1|DBSCAN-SWA
MERVMVQASTVARAKRLVADVRFGEAPREALLAYKEALDEPEFGAFLERIDPRIVRYLRVAPGGSQALSDPKGKDLLLYLHPLPGERQMRAAYEVAIEGFLEHLETRGYPVVERGAGWVKVYVSPKAPSLDLEGAWKAYIEEAFSLEGLSARLLPLLNSVRLAGRGISAPKVPVPTLGARDFLAAWYLANLLSVKERLAWRDQEIRRLEEEVSRLPEGSERSRKLRELEKRRQDQEKELKKYGGELRKKWEEIVRKEAEKAEKRRRLEERLQRAKPKDKARIQDELRALESPLAEWALEGLGKAKDDPGRLWTWLDPESPEAPGAIQRLKPYLGRFGPLAKGQLNTAVGNKFTKILEELLRLLSLSSPEVEVPPLVSETPFTLDLRDPGDKADVCYGCGRPLGKDKLKASKLVFASPSQRLQSGNGQDEPWVCPSCAALALLSPIKPGEGSVLVRVGSYGAPEAAKHFARLLVTGTLHVAAGRYLLLNSPQVGGKPLTQALGRVVYALQALGQEVNPKVLERFPFYLVEGAQEIPLPPRALWLSHVLQRAFASRPDEGGEVNRPLGEALRYALGDLPWHALYTLARRYGRVADRFSLEDGLMRYASLLEKEVGMKENTDLSQRFRDVAGLTGLLSAWVGYVEGQVGRNSQEAKRAVVKLLDNLERPGDFLYVAAYHLDSTQARLYEAGGAFFYQEAKRLLQEAGARAQEAEEGSGRFLNVSQDDLHRVYAHLAARYPGKAWEGFIYEVRLSLASRFPQYIRMEKEG
>NC_017273|89674:150987|110776_111001_-|WP_014511092.1|DBSCAN-SWA
MGRLKRLSGRELRRLLRRHGFAPIKGRGKGSHEVWRNPQGMEVVIAVHDKDIVPIGTLKGILRQAGIPEEEVRQ
>NC_017273|89674:150987|116061_116475_+|WP_014511097.1|DBSCAN-SWA
MIPERLVLDAGPLIALLHRSDPDHEEAVRGFRRLAEGGARLFLPMPVLFEVFKWLLFQAGPKAAREGLAKVEEGVVVVPFTLEDLEEVRLLLARLPGWGGTLEDAGVALLALRLGAPVWTLNYRDLGAFPALRFWTP
>NC_017273|89674:150987|150462_150987_-|WP_014509880.1|transposase|DBSCAN-SWA
MRLLAYDEHRLGLKPVYRRVWARRGERPLAVGAHRYRWFYVCTFVEPETGESLSLLVDGIDTEVMGWVLRELRAWLGEGEEAWVVLDRAGWHVSGRVEVPEGVRLVFLPPYSPELQPVERVWPLVNEAVANRYFRDLEEMMEAVAERCRVLAQDPETLRRHTLFHWWPRTKELA
>NC_017273|89674:150987|131908_132850_-|WP_014511110.1|integrase|DBSCAN-SWA
MVAAQDPHAELLHRFRRYLEMEEGRSPRTAKEYLMDAGLFARWFRERHGRPPRFEEVGSQHIRAFLASREVSPHRAGRVLASLRKLFRYLAEVEGLPILKDPTEGVKRPKLPRRLPVYLTPPEVARLLQAAYQNRSPRVALRDWALLAFLYGTGLRLSEALALTYADITYQDGIPHAIRVQGKGGKERVVVLSPTAQRALHQWLKHRNLEGHPTSPYIWSHTTGPNRGKPFSARAVEAMVKRVARRAGLKDWRRITPHKLRHSYASALVEAGRGIDEVKELLGHSSISTTQVYVHVSRKRLEEAARALPDVVG
>NC_017273|89674:150987|103912_106480_+|WP_014511089.1|DBSCAN-SWA
MRAEDPGLIHVTPNRAVARRLGVPYRTLAGLARELLRDGGLLVASPYRARRLLVQAVREALAPKDPQGLAAALEGPVRTLLLLAQASGQGEEALARLAEEASPRLARVARAARRYGELLRGRRLLDPVEVLPKAAALGKRLPLRLWRYPYLGTGELAFLKGVAAPGSEVELLLPEGAWGEANRRAKEALEEVGLKVRPLELAGLGRAFLQGGGVGRVQALRFPDMEAEVRHVLASLKGLLRGGLPPGEVALVARDDRRYGPLVAAVGFDQGLPVRLLYRVPVGESRVGSLAALLAQALQDFPYEATLRLLFHPLFPWERKVDLDQARLRRPSGEAWKGLGLPGELLELAQGKTGGELVQGLRRALSPLRKRLEGWPRERAALEALLEGLGELEEEDREGFFQGISELLYHLTVPAQPGYGGVELHTPLARYGGAFRHLFVLGMAEGLTPVPVAEDPFLGLSEVEELERFGLFPEKPWEAAAREALVFAALLGSLKEDGEAVLTYPEVVEGRPVPMSPFLERLGLEPRSPGRTLVGSLVEARRLGLWEGDPLQEAMERALEAERARLEGEASSPHHGATGRPFLPASLSVSQLEDLATCPFRFYAKHLLRPRGDREAGDGDREDLGTFVHQVLARVFRAALEKDARRGEEVRALAAGGLLGEAFSRVEEEWKGRPNSPFFLRRPDWPHRRRWVLGLLARAFEDDKQFLRGDVKIVGVEVEAKLGRGFRGMVPGYEGLEVRGIIDRVEERSGSRFYLDYKLGSTSPRVKDPRTGKLSADLQLSLYILLHGEGRGAGVYYLLASREAKTVNLDRGALWAIFKEIRRTLKSGAFEPRPDAKAEACRSCPVELLCRYEGR
>NC_017273|89674:150987|91810_92233_+|WP_014511082.1|DBSCAN-SWA
MGNNINFSDYFRESMKDPEARRLYREVLDEELSWLLSYLREERRLSQKEVAERLGVSRGRVSQLETSAGLSMSLESLARYAQALGLSLRLEFADERGEVLARFSLAADEPVAETTNPAWENAGAGWEPASGKASWASWAA
>NC_017273|89674:150987|147346_147874_-|WP_014511121.1|DBSCAN-SWA
MSKPVVVYTDASVDTERGVGGLAVLGLVQAKGGGRFSASLSLPVEDSTLAEVMAVKLALEVVLVTLGPGTQVTLFCDNESVVEHLQNGKRNGRQDLNRALEGVARLRGLLRVTFRHKPRCSTPEMRWVDARAKEALEWARKGGPIVPGIQASKPEPSRAKPKGLLWRILRWILGG
>NC_017273|89674:150987|138954_140715_-|WP_014511116.1|DBSCAN-SWA
MAKRLKPVDVVLVGVGWTGGILAKELAQAGYRVVGLERGHYRDTIPDFQLPWIHDELRYAVRYELMQDLSRETITFRNNRNQTARPMRVLGSFLPGEGLGGAGVHWNGVTWRFLPYDFEMRTKTLERYGPSAIPEGSTIQDWGITYEELEPYYDKFEYTCGIAGKAGNLKGVIQPGGNPFEGPRNREYPNPPMKTSYAGHLFRQAAQELGYHPFPQPSANVTQPYTNPDGVQLGACVYCGYCERFGCEVNAKASPQTTVLPVAFRTGNFELRTEAYVTRINLSPDKRQAVSVSYVDLKTGEEYEQPAEVICLTSYVLNNVRLLLLSGIGKPYDPVTGQGVVGRNYAYQAFTSVVLFFEDKVFNPFMGAGALGVSIDDFNGDNFDHGGLGFIGGGNIACSTTGARPIQSLRVPPGTPRWGAEWKKAVARYYQRNFSISFQGGVLPYRTNYLDLDPTYKDAFGLPLLRMTFDWGPNEHRASQFAAQVLERIARAIGPKTYVINRLSEHYSIVPYQSTHNTGGAVMGSDPSTSVVNKYLQSWDVPNVFVVGASAFPQNAGYNPTGTVGALAFWAADAVKRYLQRPGPLV
>NC_017273|89674:150987|106483_109528_+|WP_014511090.1|DBSCAN-SWA
MEANLYVAGAGTGKTYTLAERYLGFLEEGLSPLQVVAVTFTERAALELRHRVRQMVGERSLGHKERVLAELEAAPIGTLHALAARVCREFPEEAGVPADFQVMEDLEAALLLEAWLEEALLEALQDPRYAPLVEAVGYEGLLDTLREVAKDPLAARELLEKGLGEVAKALRLEAWRALRRRMEELFHGERPEERYPGFPKGWRTEEPEVVPDLLAWAGEVKFNKKPWLEYKGDPALERLLKLLGGVKEGFSPGPADERLEEVWPLLRELAEGVLARLEERRFRARRLGYADLEVHALRALEREEVRAYYRGRFRRLLVDEFQDTNPVQVRLLQALFPDLRAWTVVGDPNQSIYSFRRADPKVMERFQAEAAKEGLRVRRLEKSHRYHQGLADFHNRFFPPLLPGYGAVSAERKPEGEGPWVFHFQGDLEAQARFIAQEVGRLLSEGFQVYDLGEKAYRPMSLRDVAVLGRTWRDLARVAEALRRLEVPAVEAGGGNLLETRAFKDAYLALRFLGDPKDEEALVGLLRSPFFALTDGEVRRLAEARGEGETLWEVLEREGDLSAEAERARETLRGLLRRKALEAPSRLLQRLDGATGYTGVAARLPQGRRRVKDWEGTLDLVRKLEVGSEDPFLVARHLRLLLRSGLSVERPPLEAGEAVTLLTVHGAKGLEWPVVFVLNVGGWNRLGSWKNNKTKPLFRPGLALVPPVLDEEGNPSALFHLAKRRVEEEEKQEENRLLYVAATRASERLYLLLSPDLSPDKGDLDPQTLIGAGSLEKGLEATEPERPWSGEEGEVEVLEERIQGLPLEALPVSLLPLAARDPEAARRRLLGEPEPEGGEAWEPDGPQETEEEVPGGAGVGRMTHALLERFEAPEDLEREGRAFLEESFPGAEGEEVEEALRLARTFLTAEVFAPYRGNAVAKEVPVALELLGVRLEGRADRVGEDWVLDYKTDRGVDAKAYLLQVGVYALALGKPRALVADLREGKLYEGASQQVEEKAEEVLRRLMGGDRPEA
>NC_017273|89674:150987|147953_148760_-|WP_014511122.1|DBSCAN-SWA
MLWDDDMGWEIEEDLDWEDREALEEYRYWLDWADGVLNQDPEPGEASEAEAEVDLLPGPELPEEVLEALAEAPLAYGWSLTEALQELEQEAGMFLEGRVRVKLHLLRLLLGLLPLAEDEPLLKLRVREDAASEPRLVPLTKGDLRRVVEGWLELYALDFPSQVYEEMKAFRRFLERSLWEKHPALAPLLLVCTALWDHLEALHDPDLDLPPWAPALVREALKRRKRALKRRFGPNDLAAFGLTQSLEESDDLYELVALEAFLGLAEGE
>NC_017273|89674:150987|115834_116065_+|WP_011229075.1|DBSCAN-SWA
MMMCDMRVTIYLPDHLAQEVEAYRKARPGLSLSALVRELLERELVKRPEALLEVAGLVERAELSAREHDALIREER
>NC_017273|89674:150987|140718_141519_-|WP_014511117.1|DBSCAN-SWA
MNRRRFFKLVGAAAGFTVLTPGAQAQAKGHPHEAQAAPAQVSPQKPQALPVRPEAYNFFSPEEAAFVEAAVDRLIPADELGPGGREAGCAYFIDQQLAGAYGAAAKWYMGGPWGESTPQQGYQLPLTPREVYRTGIAAVNRYCQLTYGHSFAQLNPEQQDEVLRGLEAGRIDLVSLGGPPAQTFFNMLLGNTVEGYFSDPVYGGNRNKVGWRLVGFPGVAAAYVSFIENFNQPYEVEPVGIADVAGGVVDLDEHGHPIHRPLAKRR
>NC_017273|89674:150987|89674_91261_+|WP_014511080.1|transposase|DBSCAN-SWA
MKAKPKAARKRTSQKRAKAFTGVHALLLFPSGEDHKATLDLMRRFSAGVRYAYNRLLEGQTREALKRENGPLRTFFRLNTRYADDAVMKAQAVLDSARERGEDPRKVVFGGRKLFETLRRRHLSGKPLKEVKREWKEKRQGLLYSRGDRTKGGNLNLRLEAEDGALWLRVNLGNGRYAWALVKTSHPNLSALVERVHASLPYNVELSLKDGKVHATFTWEEEPTPLAATKENGVLGIDVNSDPYHLALAVVGPDGNLKRHLTLSLEEVDRAPNRGTKELLLWKIAHQVVSLAEEHGVAVATERLKHLPKGRRGDGSGRAFRRKQHRFAYASLLRKVHSLARKKGVQVVEVNPQDTSAIGMLKYAPQLSLSKDVAAAYVIGRRALGFKEKLPKGYGKLLRDERFRDHAQGFYASRVRELQAKKAQEQNPYLRRRLSREIGKAKRHLSLLSSLQGSPGSQEGSTEGRNLLGGNPWRVLRVGLFLPLLGREVPRDLSPLKVILHRGAWEGWKGGLGPPPGGGPKCANVHFG
>NC_017273|89674:150987|98977_101743_+|WP_014511087.1|DBSCAN-SWA
MEALERAFAENPLTLEDFPGFFLEATGHEPYPWQEALLRRVVREGWPEAVAVPTGAGKTMVLAVALFLMALDPKAHRRVVYVVNRRLVVDQAHEVALGLKERLEEALARPSGEATPLVRAARRLAALGGGKPLEVVRLRGGVPRPRPTLQDPARPAVVLATVDMAGSRLLFRGYGVPRGLLPVEGALFGTDALYLLDEAHLEAPFLATLEAVAGLPGPWGRPGVRAVALTATPEGLGRGGIFRLGEADARHPRLGRILTASRRVWLRESPSRRRGKDLVAHALRLGEELGGPVAVVANRVGRALEVYRELGRAFPGRALLLTGRMRPRERDLNFARTRALQERLNRGEVAFVVATQALEVGADLDFAGMVTELADLSALKQRLGRVNRRGQRERAEVVVLGERETEAKEARPYLPEALQATWAWLAGLGAEGGVDLSPEALAQRMEAQPPPSEAFGRPRPPMPFLEAFLPLLAHTDPLVPLDPGPFLHGLERAAPEVEVVWRADLPETAEEVEAYLEAAPPGPKEGVRLPLYAVRAWLQGGAADLADLEGQEEEALRPGPPREGKAFRFDGEGVEEVSLRDPRLRPGDLLLVPAGFGGLSEGHWDPEAREPVPDVAEWGEERPRFLRLHPKVLAQALEDPEGAEGFGQELKERLLGAEGRREAREEVRRFLEERLSDFRAEWRPLVQAFLEGPFEVWPWGEGWGYGGYVLRLRQENPLYGSGRPEALEAHSRKVAEAVEDFARRLGLDPGVRAPFRRSALWHDLGKQDPRMQFWFLLSAGEAVDPSSRPLAKSGTRLTRKELERLRKEAGYPLGQRHEHVAARPLLGSHPLEAHLVATHHGRGRPLPAPSPDAPGFSVPLWAPWASWPGPPYGESAHGLERLESGYLENFLGLLKGMGPWGLAYGEALLRLADYLASGGEA
>NC_017273|89674:150987|97617_98991_+|WP_014511086.1|DBSCAN-SWA
MYLAFFVRYAVDAHRGKGPRGREFPPHEVRLRGGLVRSWALEGKPEEATKALEWLETLPPPGVLAPRVLEGNWRTRVAYVPPHDLPQPPGHREKVPLLHHVLPLSGRLLAYAYPLEGREEEAEAQLPTLGRLAGRISYLGTSRNLVWVEARLVEDPLGAYREEAGQEPWLLVPAEAGDLWMRVAPPGFLRLAEERFQARVRELPHRWVPYREPEALRSSQSLSPWGAWRVLALDPPLPLEWAPLFAHAARRALLSLLPPGAPPELTGHGAGGGPLRAPHLALVPLPNVGHRYGDGRVLGLAFLLPREAGGAVELALLEALLRLEEVRLDGLAVRLLPPDGRWALREGRWRRPARRFASVTPVVFDRYPKRGDVLAALRFSARAAGFPEPEEAWVLPYPRPQGVPLSRDFRLPPGVEGYVAHAEVLFPEPVSGPVLLGRGRYLGLGLFVPLEVEDGGA
>NC_017273|89674:150987|109711_110065_+|WP_029766039.1|DBSCAN-SWA
MTERFLEVAKVSEAPLRARQAFPFPVRALHADATSFHVHGRYEGGEEEVGVLRIVHGDSRDHRPDLKPWGMGLVCADTEGHPPPLRSPGREGQRRQDPGGPVVPLPGGPGPLGGGLS
>NC_017273|89674:150987|131499_131862_+|WP_014511109.1|DBSCAN-SWA
MKRKRLAELVREEAGDLQEAPAPREERPGEAPHGGGLEGSPPGEGQGERPLPPYLTYVRKECRLRPDQLDALTALARRLNRERRGKGERITENTLIRWAVDMLLENYRNSDIFHSEDKGD
>NC_017273|89674:150987|124681_127135_+|WP_014511104.1|DBSCAN-SWA
MGEGIGRVFFLKDKVGFQPLSNHQGLVVKLLESWREGDEPLALSPKTKERLLLAARYHDDGKRFTFRIVPDGKGGLTYSFRGHRFRVAQAVQDPYAQALIRGHHDYSTREVVNLAADFLEEGLGHRFPEDLFLLMMADQLEAELAVRLWQGQAGEVRPFVEFDLLPDGEGGFLLDPWPFRVDEVALDFLVYFHPYRGEEAEVVEGWGRALVGALEEGKVPEAFQEETRRVRLRPWAAEARKADDPEAFYARFGLEPTPFQREVFKVAEGDPAHLLLAPTGTGKTEAAAFPALARGERLVFVLPTRSLVDDLEGRFRRYLKILAQEEGRPKALVVDTGHRQARFRFSPDGQEEATKERHLYHADVILTTLDKLLYRYFGYAEGVKSYTFPRRIHDRRTLFVFDEVHLYEATAWANFRHLIASLYKAGVRFLVMSATMPGTYREELLLEGTLEHPPAKRPSRVLRYMPQGNPMEIIQSHRGKRVLVVLEEVKEAAELYKRLKGEGVFLYHGRLAEGQRRRVFGEVKRRDEAQEPYLLITTPAIEVGVDLDAEVLVTTLCPPENLLQRLGRVNRRGRGQGEAYVVGETYPDYLGSLPEGYLELLKALDGQDLAQGGEERLRQAIRYPKYLDPRAETFFEALQEYVYGLDLTQEPLHRKGFVATRGWTPSVRLRQGEDEVEVPIDRLVGRKEELTPVRVVERLLTDGERGNRRWEEVPLRSGELYGRELVVDYPYPYDAELGFVELPKVFQRLRHPDPQRVQLLYAPEKDAGETPEGVMDTDQVTGGGRRVLWYLGESAWAESAKSGEVAEETEEEEEEGD
>NC_017273|89674:150987|131065_131503_+|WP_014511108.1|DBSCAN-SWA
MKGYGVVVVVDTPPALRSEALEAVLRAADYAVLPTPPAPLDLEALVETVRRAVRPLGVAHRVLLTRVDPRSLGEALEAQTALMEAGVPAFHAFVRAYKAHERAALDGKPITRWRGPNAREAEADYRRVAEELLRELARTPERREA
>NC_017273|89674:150987|117549_117834_-|WP_011174371.1|DBSCAN-SWA
MRELYLVIAYDTPDDRRRARLAKLLKGFGERRQYSVFEARLTREQWAHLKGKLEALVNKEEDVLAVYFLPPEAVGRTWRIGHEGLKRLEDPDFV
>NC_017273|89674:150987|91438_91798_+|WP_014511081.1|DBSCAN-SWA
MAQYRVELYRDARGYSQVLEFFNTLKRSNPKLLAFAQRLLKNLEEHGPDLRPPLAKPLKGLQAPIWELRHPSGLRLYYWRQGATLFVVAAGEVKKRDEADPDLLEFAVKAYRESQRNVN
>NC_017273|89674:150987|115570_115759_-|WP_008633013.1|DBSCAN-SWA
MRLEGGGAWATAEVQVEALPARVVLSACSEGGACRSLALPREGGPFRLEGLSLAAKLLRYFC
>NC_017273|89674:150987|92846_96101_+|WP_014511084.1|DBSCAN-SWA
MALSNREIVGKGLDLLRSGLRPFVEREYRRVYGEEWVREAGEVLKGDRASLQDPDAQALLKLMDYRWNEVFDEKLGRWGRTLVKELLEFRNRWAHQGAFSFEDAHRALDSMTRLLEMIAAEEAQETVRMARELLRRRFEEEAKREAERAVKQSLAVVPQGLKPWREVVTPHPDVASGRYSEAEFAADLAQVHRGEAGEEYGNPLEFYRRTHLTSGLKRLLLNALKRLAGEGGDPVVELQTAFGGGKTHSMLALYHLFGGAVDPGEVPGLEDLLAQAGVARVPLARRAVFVGTAFSPARPHPKPEGVVVRTLWGEIAYQLGGVEGYRMLEEEDRTGVAPGSDVLKELFDRFSPALVLIDEWVAFLRNLYGEEGLPAGTFDQNLTFAQALTEAAKRSPRALVVASLPASDAEVGGGGGREALLRLQNVFGRLESVWQPATQDETYEIVRRRLFQPLSAEGYRVRDAVVREYVRYYREHRGEFPSEVLEPRYEERMRLAYPIHPELFDRLYEDWATLEGFQRTRGVLRLLASVVYTLWVRGDTSPLILPGGLPLDADGPRYELVRHLSRHQEGFDQVIDSDIDGPNAKAFALEKERPSLGRHQAARRAARAVFLATAPAGAAPTGKPRGVEGVRVKLGVAHPGESPALFTEALKALSERLVYFHAEGDRYWFETRPSLNRMAQDRAAAVSREEALMELEERLRAWAKGRPALFQGVHAAPAGSGEVADEPSLRLVVLSPRTPYAKGGSEAERWAREVLEGRGRAPRRYRNTLLFLAPEAVLVPDLEEAARQYLAWRSIWEDRESLNLGAADVRQVESRLRQAEDTLRLRLEEAYRHLLVFHQPDPKAPDLEVDALRLLGSGNPLERAASKAQNEGLVLVRWHPEFLGETLARYGFWEVAEPEGVLPLRRLWEDLASYLYLPRLKDEGVLLATVAQGVKEGRFGYAERLEGGVPKGVVLGEEVAPSLGGYLLKPEVAARFLKEKTGEDVPPPPDGEGDDEKVPVPPPPRPSRPRRFYLKKTLRMESLLPEVRALAEEVLLHLYKEGGVRLEVVLEAHAEAPEGFPEDLERVLRENSRVLGAEAFFEED
>NC_017273|89674:150987|149059_150145_-|WP_041445145.1|DBSCAN-SWA
MGSTSELSAAKASGGMTLEEARSFLRRLKSRRDKEEGARPILQVWQGGALSGVLLAGEVALLYGEAKVGKSRAAVALLGWPDGERAAPDSPSEDGGDAVRSRSWRVRAPLDLRFYLYHATETRYAHLRKYAQTLGAEGLTEHILPFNDVGELERALQAIQRLAEEKKAPALVVVDSLIKLVPPQQSENEAKAMDEVMARLKRAISPSEREPLVGLVVIHHATKGNSGPRGSGAIAANADHIFRLEPRREGEEDWGLLLYERGRGDVWREVEEVLRVRVRGLRRASSSSAKGVKRASKRSRESYIERARERFGGRIFSEEELFRYLTDELGLPESRARGNISLWKSREKLLSQGEGLFFKKG
>NC_017273|89674:150987|117830_118829_-|WP_081466159.1|DBSCAN-SWA
MAEGGGGVGVVYVLENEAYLSKEGGTLKVSRRAGREVLLQKPLIAVEEIVILGNAVVTPALLKHCAQEGVGIHYLSRTGTYYAGLTRTPSKNAPARVAQFKAHLEPTWKLALAQRFVLGKIRNGLVFLRRNGAEGWEGLKEALLEAERAQDEEALRGAEGRAADLYFRAFAELLPEEFAFGERSRRPPRDPANSLLSLAYTLLAKQCESALLVAGLDPYVGYLHEVRYGRPSLALDLMEEFRSVLADSVVLSLLNNRRVILEDFDDSEGFPRLRKEAWPKFLRAWEERLNERIQHPLLGKRLAYREILLAQARILVKHLLGELPRYEPFAVR
>NC_017273|89674:150987|92236_92794_+|WP_014511083.1|DBSCAN-SWA
MESKSETIRRLYREGKSVSEIAKSLGLSYQRVYNTLKRSGFLKPKGRGPSPSGEPDPEAYARFLQGLEIRSMELMEVHAKLERSPKGKLSFRMGLEAFGPEPREGGFSAGLALSLDFQDEEGPFGFLRLRVRAGYATPLFPDEPLFRTFRERNLIVHLWPYLRLYVDFLTAQMGLPRLVLPAWKV
>NC_017273|89674:150987|130329_130572_+|WP_014511106.1|DBSCAN-SWA
MELAKLSRKGQLSIPKRLLKALGVEGEAYFLVELAPEGGLLLRPAGVYPLEVYTEERLQELLAEDTLTEEERTRLAALAR
>NC_017273|89674:150987|114652_115132_+|WP_124105779.1|DBSCAN-SWA
MQQDREHPLYYLDAETLLVATYIWVDDELKALQAQDFKLPPKQKHQKATLAELLTLAIFLLLQGQDLAKGYLAAKTTLKAYFPSLPHLSRFYRVLQKAQGLLAHLAMRLSGGQGLLQVVDLKPIPLAHGHRIHGLSLPEAAMGVGPLGAFAGYVHKLFP
>NC_017273|89674:150987|144775_146944_+|WP_014511120.1|DBSCAN-SWA
MLSPFGGEEETKAIPLEEEILLAWRVFSAALPPNFLAPVSASLHTLVREAEGKEGAELEAYAWERLEELARTSVVKDAIQSFLEVAAEKPEVLRAGLLWFRTWNRLSPEEREALYRKAERFKPTAELASKASFLQGPPPPPKPLSPSVQAARSSPPRFTPTPEQEEAVRAFLSREDMKLVAVAGSGKTTTLRLMAQSAPKERLLYVAFNRSVRDEAERTFPGNVEVLTLHGLAHRHVVRGSGAYQRKLAARNGRVTPGDVLEALELPRERYALAYVIRSTLEAFLRSASEVPTPAHIPPEYREVLQRRDKDPFSERYVLKAVRLIWKLMQDPDDSFPLSFDGFVKIWAQAGAKIRGYDAVLVDEAQDLSPVFLQVLEAHRGELRRVYVGDPRQQIYGWRGAVNAMDKLDAPERKLTWSFRFGEDLARGVRRFLAHVGSPIELHGKAPWDTEVSLARPEPPYTALCRTNAGAVEAVTSFLLEEGREGARVFVVGGVDEIAWLLRDAHLLKVGGEREKPHPELALVENWEELEELAKEVNHPQARMLVRLARRYDLLELARLLKHAQADEEGKADLVVSTLHKAKGREWDRVVLWGDFIPVWDEKVREFYRKQGALDELKEEENVVYVALTRARRFLGLDQLPDLHERFFQGEGLVKPPSVSPLSVGGAGVSADLLRELEVRVLAKLEDRLKEVAEVLAALLVEEASKAVAEAMREMGLLGEEG
>NC_017273|89674:150987|142382_143474_-|WP_014511118.1|transposase|DBSCAN-SWA
MEQLTPLINALKRYWKADLRRLTFLAALVMALVTARTTSGPRLALSLGSIASPDPRSAYRRFQRFLAWPGLDGEGYARFIFALLRPQGLLLVMDRTEWELGKSKVNLLMLAFLYQGLAVPLFWSFLPHDGNSSTPERIALMERALAFLRAHFPHLRVEGFLADREFIGEAWFRYLEEKGIPRCIRIKANTRMWRLGSGPRAWELFASLKVGESRVPRRRYWVYGRRMWVVGLRLGVREWLIVATDLDPHRVLEVYGLRWGIERLFGALKGRGFDLEATHVTRGERLSRLLVPLSLAFVWAFRTGLVLHRVRPVRPKKHGRLGQSLFRAGLDLLTLWALALWGAGGGRRGSPLGLCPMEVLACT
>NC_017273|89674:150987|101739_102750_+|WP_014511088.1|DBSCAN-SWA
MSAVWLEGLSLEGFPVAALAAYGALRLLVEEEGMEGVRLVFRDPQSRPVPGLLGVGEGELLCRLARRLRRVPPLPPELLEREKLEGLSPEEMRRLASADPRARRFLPALLLPLPGGGAFPSPLDTSKGQQRLTKTLRENWEAARRTHLLKGLRRVLFSGVLLGPGEVLWTWARVRGRASRRRSPLEFGLVGWHPSQYRQWAEGAREPSGLPFHEKVRIHPVATLLAWEAVPLFLLYPAPDGVRAAGVHDPEGRPSLLLPTPGHPVSLEALRALLLQAPLALQDPRAWPPEVALWRSPRLGHPKRQKDPYPVYVEARPVLRGPQAGAQTPGGSRRGR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014511080.1|89674_91261_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_014511081.1|91438_91798_+	hypothetical protein	NA	NA	NA	NA
WP_014511082.1|91810_92233_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014511083.1|92236_92794_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014511084.1|92846_96101_+	ATP-binding protein	NA	NA	NA	NA
WP_014511085.1|96535_97618_+	CRISPR-associated protein	NA	NA	NA	NA
WP_014511086.1|97617_98991_+	type I-U CRISPR-associated protein Cas5/Cas6	NA	NA	NA	NA
WP_014511087.1|98977_101743_+	type I-U CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_014511088.1|101739_102750_+	hypothetical protein	NA	NA	NA	NA
WP_014511089.1|103912_106480_+	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_014511090.1|106483_109528_+	AAA family ATPase	E3T5J8	Cafeteria_roenbergensis_virus	2.5e-07	27.1
WP_029766039.1|109711_110065_+	hypothetical protein	NA	NA	NA	NA
WP_014511091.1|110221_110692_-	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_014511092.1|110776_111001_-	addiction module toxin, HicA family	NA	NA	NA	NA
WP_014511093.1|111135_111687_+|transposase	transposase	NA	NA	NA	NA
WP_014511096.1|113211_114177_-	recombinase XerD	NA	NA	NA	NA
WP_124105779.1|114652_115132_+	hypothetical protein	NA	NA	NA	NA
WP_081466172.1|115345_115525_+	hypothetical protein	NA	NA	NA	NA
WP_008633013.1|115570_115759_-	hypothetical protein	NA	NA	NA	NA
WP_011229075.1|115834_116065_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_014511097.1|116061_116475_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_011174371.1|117549_117834_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_081466159.1|117830_118829_-	CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_041444555.1|118798_119383_-	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_014511101.1|120738_123039_+	hypothetical protein	NA	NA	NA	NA
WP_081466160.1|123800_124715_+	hypothetical protein	NA	NA	NA	NA
WP_014511104.1|124681_127135_+	CRISPR-associated helicase Cas3'	A7WK98	Acidianus_filamentous_virus	2.4e-05	23.5
WP_014511105.1|127134_127929_+	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
130250:130283	attL	NA	NA	NA	NA
WP_014511106.1|130329_130572_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_014511107.1|130552_131008_+	PIN domain-containing protein	NA	NA	NA	NA
WP_014511108.1|131065_131503_+	ParA family protein	NA	NA	NA	NA
WP_014511109.1|131499_131862_+	hypothetical protein	NA	NA	NA	NA
WP_014511110.1|131908_132850_-|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	9.9e-16	29.6
WP_014511111.1|132852_133329_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_014630458.1|134817_135138_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_014511107.1|137004_137460_-	PIN domain-containing protein	NA	NA	NA	NA
WP_008633599.1|137440_137683_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_014511116.1|138954_140715_-	GMC family oxidoreductase	NA	NA	NA	NA
WP_014511117.1|140718_141519_-	gluconate 2-dehydrogenase subunit 3 family protein	NA	NA	NA	NA
WP_014511118.1|142382_143474_-|transposase	IS4 family transposase	NA	NA	NA	NA
WP_041445142.1|143659_144760_+|transposase	transposase	NA	NA	NA	NA
WP_014511120.1|144775_146944_+	AAA family ATPase	A0A126DN25	Acinetobacter_phage	2.8e-53	31.3
WP_014511121.1|147346_147874_-	hypothetical protein	NA	NA	NA	NA
WP_014511122.1|147953_148760_-	hypothetical protein	NA	NA	NA	NA
WP_041445145.1|149059_150145_-	AAA family ATPase	NA	NA	NA	NA
WP_014509880.1|150462_150987_-|transposase	IS630 family transposase	NA	NA	NA	NA
161598:161631	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_017273|350853:396075|DBSCAN-SWA
CTTGAGGCCCTGCTGGAGAGGCTTTCCCGGGAACTGGAGGCCCACCTGGCCTCCTTGCCTTCCCCTGAAGAGGATGGCCCTCCAGAGGGTGGAAGCGAGGAAGGGCAGGAGCCGGGACGTCCCCAGGCCTCTTCCCCGGGAGCCCCTCCCGGGGCGCTTTCCCCCCCACCTCATGGACACCACGGGGCTGGCCTACCGGAGCAAGGACCGGCTTCTCCGCTTTCGTCGGGGGAAGGAGGTGCGGCGGGTGCGGGGGCACGCGCGGCTTCTGGCCCTGATGCGGTGGGATAGGGAGAGGCGGCTCTTATGGCCCTGGGGTGGAGTGGTGGGGGAGGGCTACGCCCCGGACCCCCGGCTTGGGGGGGAGGTGCTGAGGCGGTTTCCTCCTTCCGGGGGGTGGCTTTTGGCGGACGCGGGGTTTGACGGGAAGGAGGTGTGGGGGGTTTTGGGGGAGGCGGGGGTGCGGCCGGTGATCCGGCTTCGGGGCGGGGGCGAGGCCAGGGAGGAGGCGCGGGTGCGGGCGCGGGAGGGGTGGGACCCTGAGGTGTACCGGTTTCGCGGGGTGGTGGAGGGGGTGTTTGGGGGGATGAAGACGCGGCTGGGTGGGGGGTACCTTTGGGAGCGGAAGCCTTGGACGGCCATGGCGCGGGCGCTTTTGGAGCTCATCGCCTACGGCCTTAGGGTTCTTCTCTCCCTTCTCCCGCCCCCTCCGGGGTACAAGGCAATTTACTAGGCAAGCCCAGGGGCCACGCTCTTCGTCGTCGCCGCGGGAGAGGTTAAAAAGCGGGACGAGGCCGACCCCGACTTGCTGAAGTTCGCGGTGAAGGCGTACAGGGAAAGCCAGAGAAACGTTAACTAGGGGGGACTTGTCATGGGAAACAACATCAACTTTAGCGACTACTTCCGGGAGTCCATGAAGGACCCGGAGGCCCGGCGGCTTTACCGGGAGGTCCTGGACGAGGAGCTCTCCTGGCTTCTCAGCTACCTGAGGGAGGAGAGGAGGCTTTCCCAGAAGGAGGTGGCCGAGCGCCTCGGGGTCTCCCGGGGCCGGGTGAGCCAGCTGGAGACCTCCGCGGGCCTCTCCATGAGCCTGGAGAGCCTGGCCCGCTACGCCCAGGCCCTGGGGCTTTCCCTGAGGCTGGAGTTCGCCGACGAGAGGGGAGAGGTCCTGGCCCGCTTCTCCCTCGCGGCGGACGAGCCCGTGGCGGAGACGACGAATCCCGCTTGGGAAAACGCCGGGGCCGGCTGGGAGCCTGCTTCCGGCAAGGCCTCCTGGGCTTCTTGGGCCGCCTAGAGCATGGAAAGCAAGTCGGAAACCATCCGCAGGCTTTACCGGGAAGGGAAGAGCGTCTCCGAGATCGCCAAGTCCCTGGGCCTGAGCTACCAGAGGGTCTACACCACCCTGAGGCGCTCGGGCCTCCTCAAGCCCAAGGGAGGGGAGCCCTCGCCTTCGGGGGAGCCCGATCCCGAGGCCTACGCCAGGTTCCTCCAGGGTCTGGAGATCCGGTCCATGGAACTAATGGAGGTCCACGCGAAGCTGGAGCGTTCCCCCAAGGGGAAGCTCTCCTTCCGCATGGGCCTCGAAGCCTTCGGCCCCGAGCCGAGGGAGGGGGGCTTCACCGCCGGGCTCGCCTTGGGCCTGGACTTCCAGGACGAGGAGGGGCCCTTCGGTTTCCTGCGGCTTAGGGTGAGGGCCGGCTACGCCACGCCCCTCTTCCCGGACGAGCCCCTCTTCCGCGCCTTTAGGGAGCGAAACCTGATCGTGCACCTCTGGCCCTACTTGAGGCTTTACGCTGACTTCCTCACGGCGCAGATGGGGCTTCCCCGCCTGGTCCTGCCCGCCTGGAAGGTCTAGGAGGGGTCGCCTGCCGCCCCCTTGGGCCGTTTGGGGGCTTAAGCTTTGAGGTATGGCGCTCAGCAACCGGGAGATCGTGGGCAAGGGCCTGGACCTCCTTCGGTCCGGGCTGAGGCCTTTCGTGGAGCGGGAGTACCGACGGGTCTACGGCGAGGAATGGGTCAGGGAGGCGGGGGAGGTGCTTAAGGGGGACCGGGCTTCCCTGCAAGACCCCGACGCCCAGGCCCTCCTCAAGCTCATGGACTACCGCTGGAACGAGGTTTTTGACGAGAAGCTCGGGCGCTGGGGCAGGACCCTGGTGAAGGAGCTTCTGGAGTTCCGCAACCGCTGGGCCCACCAAGGCGCCTTCTCCTTTGAGGACGCCCACCGGGCCCTGGACAGCATGACCCGCCTCCTGGAGATGATCGCCGCCGAGGAGGCCCAGGAGACGGTCCGCATGGCCCGGGAGCTCCTCAGGCGCCGCTTTGAGGAGGAGGCGAAGCGGGAGGCGGAGCGGGCGGTCAAGCAGTCCCTGGCCGTCGTCCCCCAGGGCCTCAAGCCCTGGCGGGAGGTGGTCACGCCCCACCCCGACGTGGCCTCGGGGCGGTACAGCGAGGCGGAGTTCGCCGCCGACCTGGCCCAGGTACACCGGGGTGAGGCCGGGGAAGAGTACGGGAACCCCTTGGAGTTCTACCGCCGCACCCACCTCACCTCCGGGCTGAAGCGCCTCCTCCTCAACGCCCTGAAGCGCCTGGCGGGGGAGGGGGGGGACCCGGTGGTGGAGCTCCAGACGGCCTTTGGCGGGGGGAAGACCCACTCCATGCTTGCCCTCTACCACCTCTTCGGCGGGGCGGTGGACCCCGGGGAGGTGCCGGGCCTCGAGGACCTCCTGGCCCAGGCAGGGGTGGCCCGGGTGCCCTTGGCCCGCCGGGCGGTCTTCGTGGGCACCGCCTTTAGCCCCGCCCGTCCCCACCCCAAGCCCGAGGGGGTGGTGGTGCGCACCCTCTGGGGGGAGATCGCCTACCAGCTCGGGGGCGTGGAGGGCTACCGGATGCTGGAGGAGGAGGACCGCACGGGGGTGGCCCCGGGTTCCGACGTCCTCAAGGAGCTCTTTGACCGCTTCAGCCCGGCCCTGGTGCTCATAGACGAGTGGGTGGCCTTCCTGCGCAACCTCTACGGGGAGGAGGGCCTCCCCGCCGGGACCTTTGACCAGAACCTGACCTTCGCCCAGGCCTTGACCGAGGCGGCCAAGCGCAGCCCCCGCGCCCTGGTGGTGGCCTCCCTTCCTGCCTCCGACGCCGAGGTGGGGGGAGGAGGGGGGAGGGAGGCCCTCCTCCGGTTGCAGAACGTCTTCGGGAGGCTGGAGTCGGTGTGGCAGCCCGCTACCCAGGACGAAACCTACGAGATCGTGCGCCGCAGGCTCTTCCAGCCCCTTTCGGCGGAGGGCTACCGGGTGCGGGACGCCGTGGTGCGGGAGTACGTGCGCTACTACCGGGAGCACCGGGGGGAGTTCCCGAGCGAGGTCCTCGAGCCCCGCTACGAGGAGCGGATGCGCCTCGCCTACCCCATCCATCCGGAGCTCTTTGACCGGCTCTACGAGGACTGGGCCACCCTCGAGGGCTTCCAGCGCACCCGGGGGGTGCTCCGCCTCCTGGCCTCGGTGGTCTACACCCTCTGGGTCCGGGGGGACACCTCCCCCCTGATCCTGCCGGGGGGCCTTCCCCTGGACGCCGACGGCCCCCGCTACGAGCTCGTTCGCCACCTCTCCCGCCACCAGGAGGGGTTTGACCAGGTGATTGATTCAGACATAGACGGCCCCAACGCCAAGGCCTTCGCCCTGGAAAAGGAGCGCCCTTCCCTTGGCCGCCACCAGGCGGCCCGCCGGGCGGCCCGGGCGGTCTTTCTGGCCACCGCCCCCGCCGGGGCCGCCCCTACGGGCAAGCCCAGGGGGGTGGAGGGGGTCCGGGTCAAGCTGGGGGTGGCCCACCCCGGGGAGAGCCCGGCCCTCTTCACCGAGGCCCTGAAGGCCCTCTCCGAGCGCCTGGTCTACTTTCACGCCGAGGGGGACCGCTACTGGTTTGAGACCCGCCCGAGCCTCAACCGGATGGCCCAGGACCGGGCGGCGGCCGTATCGCGGGAGGAGGCCCTAATGGAACTGGAGGAGCGCCTGCGGGCCTGGGCCAAGGGGCGCCCCGCCCTCTTCCAGGGGGTGCACGCGGCCCCCGCGGGCTCGGGAGAGGTGGCGGACGAGCCCAGCCTGCGCCTTGTGGTCCTCTCTCCCCGGACCCCCTACGCCAAGGGGGGTTCGGAGGCGGAGCGGTGGGCCCGGGAGGTCCTGGAGGGGCGGGGCCGGGCCCCAAGGCGTTACCGCAACACCCTCCTCTTCCTCGCTCCCGAGGCCGTCCTGGTCCCCGACCTCGAGGAGGCGGCCCGCCAGTACCTGGCCTGGCGTTCCATTTGGGAAGACCGGGAGAGCCTGAACCTGGGGGCGGCGGACGTGCGCCAGGTGGAGAGCCGCCTTCGCCAGGCGGAGGACACCCTGAGGCTCCGCCTCGAGGAGGCCTACCGCCACCTCCTCGTCTTCCACCAGCCCGACCCCAAGGCTCCGGACCTGGAGGTGGACGCCCTCCGCCTCCTGGGGAGCGGCAACCCCTTGGAGCGGGCGGCCAGCAAGGCCCAGAACGAGGGGCTCGTCCTCGTGCGGTGGCACCCGGAGTTTCTGGGGGAGACCCTCGCCCGCTACGGGTTCTGGGAAGTGGCCGAGCCGGAAGGCGTCCTCCCCCTGAGGCGGCTTTGGGAAGACCTCGCCTCGTACCTCTACCTCCCCCGGTTGAAGGACGAAGGGGTGCTGCTCGCCACCGTGGCCCAGGGGGTTAAGGAGGGGCGGTTTGGTTACGCCGAGAGGCTGGAGGGCGGGGTTCCCAAGGGGGTGGTCCTCGGAGAGGAGGTGGCCCCCTCCCTGGGGGGTTACCTCCTGAAGCCCGAGGTGGCCGCCCGGTTTTTGAAGGAGAAAACCGGGGAAGACGTTCCCCCACCCCCGGACGGGGAGGGGGATGACGAGAAGGTCCCGGTCCCGCCTCCGCCTAGGCCTTCGAGGCCCCGCCGTTTCTACCTCAAGAAGACCCTGCGGATGGAAAGCCTCCTTCCCGAGGTGAGGGCCCTGGCCGAGGAGGTTCTCCTGCACCTTTACAAGGAGGGCGGTGTCCGGCTCGAGGTGGTCCTCGAGGCCCACGCCGAGGCTCCGGAGGGATTCCCCGAGGATCTGGAGCGGGTCCTCAAGGAGAACAGCCGGGTGCTCGGGGCCGAGGCTTCCTTTGAGGAGGTCTGAGGTACGGGGGGCTGGAGTCTAGGCAGGAGGACGCGTTCTGGTGAGACTCCGTGATAAGAACTCCCCGTAGGTTTTTCCCTTACCATGAGAACATCGCGCTGGCCATGCCCTCTTCCACGGATGGCCCGGGGGCGCTGGGGAACGGGATCTGGAGGATTTCTTATTCATTCGTGTGCTACCTCAAAACTTGCACTTATGCGCCCTGAGGATACTCATGCGCCAGGACCACTTGAAAGAGGCCGCCAGTTTCCCGTCTGATGACGGGTGCCATGACCCAAGCAGCCCTATCCCTACTTTGGACCCTCCTGGCTGTTTTGCCAAGCCCCCACCTCCAGGAATCCTTCAAGGCTTTGCCCTTGCCCAAGATAGCCCCTTGGGGCTGACCTTCCTCCACGGCCACGGCAAGGCTAGACCCCAGCGCAGCAAGACCAGGTCCCCCTCTGCCCTCTCCCGCTTCCTCAACCGCTTTTCCCGCCTGCCACGCCCTGGATCCTGCTTGTGGTGGAGGAGGAGGCGGTTCACGTTAGAGGGCTTTTTCCCGGAGATGAAAGGGGGGAGGGAGCTGGTGGGAGGCCAGGGAGCGGGCAACTCGGGTTCTCTTGCCCAAGCTCGTGGGGAGGGAAGTGGTGCCAAACGATAGAGCTGTGTGGGAAACCGGGGCATTATGGAAGGGTTAACGGGTGCAATATTGCCCCTAGTCAATAGGGTTGATACTGTCTTGCCTGTCAAGCGGCCCCTTGGTGCGGCTGGGTCGCGTAGTACTCCCTGAGCCGCCCCATCATCCGCCCGAGGAGCTTGTGGGCCACGGCTAAAAGCGCCTGTTTTTTTCTCTTCCCTCGGGAGAGCAAACGGTGGTAGAAGGCCCGCATCTCTGGGTCATGGCGCACCGCCACCAGGGCCCCCATGTAGAGCTTTCACCGCAAGAGGGGAGGCCCTTTTCTGGAGAGCCGACTCCTCTCCACGCTCTTTCCCGACGCTTCCCGCTCGGGGATCAGCCCCGTGTAGGAGGCTGCCGCCTTCGCCCGGCCCCAGAGGTGGGGCGGGAGGAGGGCCAGCACCGCTGCCGCCACCTGGGGTCCTACGTCGGGCAGGGCCATCAGGACGTGTGGATGCGGTCTTTCACGACCGGGATACTGTGCGGCGGGGAGGCCAGGGCGGGTGGCTACCCATCAATCCCGCGGGCGTGGCGGCCCGGCAACCGGGGCGGTAGGGCCTCCCTCAGGGGGCAAGATACATGAACCCGGTTCATACTTTGTTTTCTCTTACTTGACAAAGTTTAACAGCTTTACTAACCTTGAGCTAAGCTCCTCCGTTACTTGCTAAGCCCTTAGGCCAGGGGAGGTTGCTCTGAAGATGTCGGGAGAAGAGCACTTACTTTTAGAAGGCTTGGGCGCAAAGATTCGAAGCCGACGTTGGCAGCTGGGGTTGACGCTCAGGGAGCTGGGTAGGCGAGCGGGTCTTTCTGCAGCCTTTTTGTCCCTAGTTGAGCGAGGGCACGCCAAACCTGCTTTGTCCTCCCTTATAAGCCTGGCGCAAGCTCTGGAAGTCAGCCCTGAGTTTTTCCTAAGCACAGGGCTATCTCATGGAAAGGAGCTCGTGAGGAGATCTTCCGAGATCATTTACTTCCACCTTGATGGGCTCCCCGTGCGGTATGCGTTCCTCTCCCGTGAAATCCCGGATAGAAAGCTGGATGTCGTACTAGTGGAGATTCCACCGGGCTACACTTCGGAGGTTTGGCAGCACCCTTATTTGGGCGAGGAGTTTATCTACGTCCTTTCCGGAAAAATCAAGGTTTTGTTAGGAAGTCGCACTTTTTGCCTTGGACCCGGTGATTCAGTTCATTTCCGCTCGGACATTAGGCATCGGTGGGCTAATACGGAGTCCGATGTGGCGAGGGTTCTCTGGGTAGGTACTCCTCCATTCTGGAGGTAGATATATGGAGAAACTGGCGTTGGCCTGGCCGGATCCGGAAGGTGTAAAAGAGCTCGGGACATTTCTCCTGCCTTCCGGGGAGCGTGTGATACTGGGTACAGCAAGGTTTCCTCAAGGCCGCCTCATACCCGAGCGCGGGTTTTCTCTTCACCAGGGCAGCGAGCTGTCATTGCTTCTTGAGGGTTCCTTGGAGGTGGAGGTGGAGGGGCGAGAGACTGGTGACATCATTCGGGCTGGTGAGGTGACGTTTATCCCGGCTGGTGTGCCGCATAGGGCCAAGGTGCTTCAACCCACGCTATTGGTTTGGGTTTGGATTGAGACAGGGAGGGAAGAGGATGGGCAGGCGGATATTGTGGATTAATCCGGTCGGCACGGACGTTTTTGATAGGGAAATGCAAGCGCTTTTCGAAGCGGAAAAGCTTCCCGACACGCAAGTAGAGGTGCGCTCGCTGCAGCGGGGTCCGCATCATCTCGAGTACCACTACTACGGCGCTTTGGTTCTGCCGGATGTGTTACACATGCTTGTCGAGGCCGAGCGTGAGGGCTTCGATGCCGCGGTGGTGGGTTGCTTTTACGACCCGGGAGTAAAGGAAGCTCGGGAGGTTGTCCGTTCTCTTCCTGTGATTTTCCCTGCCGAGGCCTGCCTTTACCTGGCAGCTACCATGGGGGACAAGTTTTCCATACTCGTAGGGAGGCGGAAGTGGATCCCCGCGATGCGGGAGAATGTGGAACGCTATGGGTTGATCCACAAATTGGCTTCCTTCAAAGAGTTGTGCATGGGAGTTCACGACTTCCAAAAAGATCCTGAAGAAACGCGACGGCGGATGATCCGTTTGGGGCGAGAAGCCATCGAGCTTGATGGAGCTGAGGTATTGATCCTCGGTTGCACCATTGAGTTTGGCTTTTTCCGAGACTTGCAAGAAGAGTTGGGTGTTCCCGTCTTGGACGCCACGGTTACCCCACTAAAGGTGGCGGAGTTGCGTGCTGAGCTAAAGCAGAGGTACGGTTGGGGCGCAAGCAAGCGTGGAGGGTACGAGACCCCGCCGCTGCACGAGATGGAAGCCTGGGGTTTGGGGGGGCAGTATCCCGGATTAGCACGTGCATGGGGAATTTCCGATGTGGGGGTTGGGGAGAAGGCGAGGAGGTGAAGCCATGAGGTTGTGGAAGCTTGGGATGGCCTTGGTCTTCATCGGTGTATTATCCCTGGCGTTGGGGCAGGAAAAGATTTTGCGGTTGGATGAGGTGGCTGTTGGGGAGCTGGATCCCGCCAAGGCCACAGATTATGCGGATTCCATTCTGATGTTCAACGTTTACGATACGTTGGTCTGGCCGGATGCCCGTGGCAAGCTTCAACCCCACCTGGCCCAGCGCTGGACGGTTTCACAGGACGGGCTCACCTATACCTTCAACCTCAGGCCCGGGGTGCGGTTTCACGACGGAGCCGAGGTGACGGCTCAGGATGTCGTCTTCTCTCTGAACCGCATGGTGGCCATCAACCAAGGATACGCTTATTTGTTCCGAGGCTGGGTCAAGGAAGCCCGAGCGATCGATCGGTATACCGTTCGGTTTACCCTTTCTGAACCATATGCGCCGTTCCTGGCAACCCTGGTCCGGCTTCCCATAATCAATAGGAACTTGGTTTTGAAGAACCTGAGGCCGGGGCCTTTCGGAGAGTTCGGGGATTACGGGCAGGCCTTCCTCTCACGGGCAGACGCGGGTTCCGGAGCCTACCGGATTGCGTCGCATGACCCACAAGCGTTGACTGTAATGGCGAAGTATCCGGCCTACTTCCTCGGCTTTGCCCAAGGAGCTCCCGACCTCGTGCGGTTGCGCTATTCTCTGGAGCCTGCCACTGTGCGCACATTAATGGTGCGGCGGGAGCACGAGGTGACAAGCCAGTGGCTTCCTCCCGAGATTTACAGGGCCTTGGCCCAGCAGGGCCTGGATCTGGTTACCGAAGGAGGCAATACCATCTTCTTCTTGAAGTTGAACAACAAACGGCCGCCCACGGATGACGTTCATTTCCGGAAAGCGATGGCCTTAGCCTTTGATTACGACGCCCTTCTCGATATCTTAAGGGTTACCGATAGGGTGCGCATGGGTAAAAAGGCTAGGGGGCCTCTTCCCGAGGGATTCCCTGGGTTTGATGCCGCCCTGCCCCTACCAAAGCGGGACCTAGCTGCGGCCAAGGCGGAGCTTGCCAAATCCAAGTATGACCCGCGGAGCATGCGGGTAGAGATCGCCTGGGTGGCGGAGGTGCCCTTGGAGGAAAAGATCGCCCTTCTTTTCCAGCAGAACATGGCTGAGCTCGGCATCCAGGTTGATGTCGTTAAGGTTCCTTGGGCCTTGATGACTGAGCGGGCGACCAAACCTGAAACCACACCTCATGTGACCAGCGTTTACGTTTCCGCTACTTTCCCAGATCCTGACTCCCTTCTTTACAGCATGTACCACTCTAAAGCGGCGGGTACTTGGCTCTCCATGTCTTGGCTTCAGGACAAGCGGGTAGACGAGTTGCTGGATCTGGGGCGTAGAACGGTTGACGAAGCTCGTAGACGCGAGATTTACGTCCAGCTGCAACGGTACCTTGTGGAAAATCAGGTGGATATCTATGGCTATGAGCAGCTTGAAGTTTTCGCCAAGCAGCCGTATGTCTCCATTCCCACACTGGAGAGCCCTGAGAAGCAGGTAGCCGGTGTTATGGCCGGAAACTGGCTTTTCAGGCTAATGAAGGTACGTCGCTAGGGGAGGAAGAGGGATGGGGCGGGCACTTTTCCGGAGGTTGGTTTGGTCCCTAGGGGTTCTTTTTGGTGTTTCGCTCCTGATCTTTGTCCTCGCGCGCGTCATTCCAGGGGATCCGGCTAGGATTGCTTTGGGACCGATGGCCACCGAGGAGCAGGTGGAAGCACTGCGGCGTGCGCTCTACCTTGACCGCCCCCTCCCTCTACAATACGTGGAATTTCTGCGCCGGGTTGTCCGAGGGGATCTTGGGTTTTCGACCTATACCAAACGCCCTGTAGTGGAAGATCTACGTGAATATCTTCCGGCTACTCTAGAGCTTGTCTTTGTGAGTGGCTTTATCATGGTTGCTCTGGGCCTTCCATTAGGAATTGTAGCCGCCCATTTTAGAGACCGTTGGCCGGACGCGTTGGCCCGCGTGCTGGCTCTTTTGGGGGTGGTGACACCGAGCTTTGTTTGGGCCATATTTCTCGTTTTAATTTTCAGTTACGCCTTGGGTTGGCTGCCGGTGATGGGTCGCCTTTCGGAGGGGCTTTCCCCTCCTCCTCGGGTTACGGGTTTTTTGACAATAGATGCCGTGCTAGCACGTGACTGGGTGGTTTTCGTAGACGCTTTGCGGCATCTTGCCCTTCCTGCTTTGGCCTTATCGCTCTCGGGCTTAGGGCAAGCGGCACGTTTGGCTCGGACCAATCTTCTTGAAACCTTTGCCAAGCCCTATATCGAGCTGGCGCGGGCTTACGGGCTATCTCCGTTCGCTATAGCTCTTAAGTATGCCCTTCGCCCCGCTATGGCCCCGACCCTCACCATAATGGGCCTTGACTTTGCGGCCATGCTTGGATCGGCCTTCTTGGTGGAGGCGGTTTTCAACTGGCCGGGCCTTGCCCGGTATATGGTTCAAGCAACGCTATACAAAGATCTAAATGCCATTGTAGGCACGGCACTGGTTGTGGCCGCCTTCTTCTTGGCCGTCAATCTACTGGTCGACCTAGTAGTTGTTTGGCTTAACCCAAGGTTGCGAATTCAGGAAAGAGAGGGGATTTAGGAGGATGCGAAGGGAATCGCTGCGGCGCTTTTGGTATCACTTTGGCCGGAATCCCTTGTCCCTTTTGGGACTAAGCGTAGTGACCTTGGTGGTTGTTGGGGCGCTGGGAGCTCCGTGGATCGCTCCTTATCCGGAGCATGCGGGCCGATTTGTGAATTTTGCGGAAGCAGGCCAGCCACCTAGCCTCCACCACTTGCTGGGCACTGATACTTTTGGCAGGGACCTCTTTAGTCGTATTCTCTTTGGTTATCGTATTTCCTTGGCGCTGGGGGTTGTAGTTCTCGGTATAGCTGTGCCGTTAGGAGTAACCCTTGGGCTTTGGGCGGGCTATATCGGCGGGGGGATCGCAACTTGGATAATGCGCCTCTCGGATGTGTTCGTGGCAATTCCTCCTCTGGTGCTGGCTATGGCGGTATTGGGTGTGGCCGAGCCCAGCCTGACCAATGCGATGATGGCGCTTACCCTGATGTGGTGGCCGTGGTACACAAGGATGATCTACAACCAGGTTCGTTCCTTGCGTTTAGAGGGCTATGTGGTTGCTGCCCAAATCATCGGGGCGTCGGCCACCCACATTATGTTTCGTGAGATCCTGCCCAATACCCTTCCGAACATCTTGACCAAGGCTGCCTTGGACATGGGATTTGTAATCCTGATTGGAGCTAGCCTCTCCTTCCTAGGGTTGGGGGTCCAACCCCCTACCCCCGATCTGGGAACCATGGTGGCCGAGGGTGCTCGCTATCTGCCGGATCTGTGGTGGTTGGCGGTCTTCCCCGGATTGGCGATCCTCTTTGTGGTACTAGGTTTTAACCTCCTGGCAGATGGCCTTCGCGATGCCTTGGGGGAGGGGTGATCGCCGTGTCTTTGCTCGAGGTGAAACAACTGAATTTGAGCCTCAGGACCCATACGGGGTTGGCTCACATTCTCAAAGACGTAAGCCTCAGGGTAGAGGCCGGAGAGCGTGTAGCCCTGGTCGGTGAAACCGGTTGTGGCAAATCGCTTACCCTGAAGGCCATTCTTGGACTTCTGGAGGGTAAAGGGTTGGTAGTTTCTGGAAAAGTTCTATTTGAAGACGAGGAAATCTTGGGCACACCGCGAATTTTGCGGCTTCGCGGAGTGCAGATAGGCTTCATTCCGCAGGATCCCGCAGCCTCGTTAAACCCCACGTTTTCTATTGCGGACCAGCTGCTCGCGGTGGTCCGACGAGTCCGAAGGAACCTCCCCAAGGAGAAAGCGTGGGCGTTAATCAAGGAGGCTCTTGTAGAAGTAGCTGTGCCTGACCCGGATCGTGTCTTGGCTTCCTATCCCTTTCAGCTTTCCGGGGGCCTTTGCCAGCGGGTCCTTATAGCCATGGCCCTGGTAAACCGCCCCAAGCTCGTATTAGCCGACGAACCAGGTACTGCTCTAGATGTTACGGTGCAGGCACAGACATTACGCGCCATGCGGCATCTGACAGAAAAAAGCGGATCTTCTGTAATCCTGGTTACACACAACCTGGGTGTGGTTCGGGAGTTTGCCGACAGGGTTTACGTGATGTATGCCGGTACAATAGTAGAGCACGGTCCTGTCAAAAGCGTTTTTCAGACACCTCGACACCCCTATACCCGAGCTTTGCTCGACTCGGTTCCCCGGCTTACAGGAGGTGGCCTGCCCCAAGGACTAGACGGCCACATCCCCGACTACACGTCTCCTCCCAAGGGGTGTCGCTTCCGTCCTCGTTGTGCCTTTGCCCGTCCGGAATGTGCGGAGGAGCAGCCTTTGCGGCAGGTGGCAGAAGGGCACGAGGTGGCGTGTGTCCTTTATGCGGAGGTGCCCCGTGGCTGACATCCTTTTAGAGGTTCGGGATCTCACCAAGGAGTTTGCTGTGGGAAGAAAGCGCGTCCGGGCGCTGAATGGAGTTTCCCTTGGCTTGGAGGAAGGGGAGATCCTAGCTGTTGTAGGGGAGAGCGGTTCAGGGAAGACAACTCTAGCCAATTTGGTTTTAGGTATTGAGATGCCGACCTACGGGGATATCCTCTATCGCGGCACACCCTTAAAAACTCCTCGACCGTTGCATATGCGGCGCCGCCTTCAGTACGTCCAGCAAAATCCGTGGACTACGCTTAATCCTCGACGTACCGTCTTTCAGAGTGTGGCGCTCCCCTTAGCGGTTCACAAGTTGACCCCTCCAAGGTTGTGGAGGGAGCGGGTGGCCGAGCTTTTACACCTTGTGGGCCTCGGACCTGAGTTCCTCGACCGCTACCCTCATGCCCTTTCCGGCGGCCAACGGCAGCGGGTGGCGATTGCACGTGCTTTGGCGGCCCAGCCTGAAATGGTAATATTGGACGAGCCTACAAGCGCTTTGGACGTGAGCGTTCAGGCGAGAGTGTTGGGTCTGTTACTGGAGATTCAGGCACGTTTTTCCTTAAGCTATCTTTTCATTAGCCATGATCTGGCTGTAGTACGTAATTTCGCGCGTAGAATATTGGTTCTTTACCGTGGTCAAGTCATGGAAACAGGGCCTACGGAGGTGGTGTTCCGGAATCCTGTGCATCCGTATACCCGCCTTCTTTTGGCTTCGGTGCCAGTAGTCTCTGAAGAGGAGGCTGCTCTTCGCCCATCCTGGCCCTGGGATGCCCAAGACCGGTTGGGACCTGGGGAAGGGTGTCCCTTCTCTTCCCGTTGTCCCTGGGCGCAAGAGCTCTGCTGGCGCGAACGGCCTTCCCTTGTGCCAATACAGAAGTCTCACTTGGTGGCATGCCACTTTGCCGAACTGTTTGTCGAGGAGGTTTCCCACCATGGATAGGCTGAAAGAGGTGCAACAGCTTTTGGAGAAAGAAGGGCTCGACGGGTGGCTTCTCTACGATTTTCGAGGGCAGAATCCGCTTGCTCTCAGTGTTCTTGGGATCGTCCATACCCTACTTACGCGTCGCTGGTTTGTCTGGGTGCCTACCGTTGGTAAGCCCCAGGCCTTGGTCCACGTTATCGAAAAAGACAATCTGCCTTGGACTTATCCTAAGCGGGTTTATGCGAGCCGAGAGTCCTTGGTAGAGGAGCTGTCTGGGTTGTTAGGGGGGGCTCGGCGTGTAGCTATGGAATACTCGCCCTTAGGTGATAACCCCTACCTTTCCCGGGTTGATGCCGGTACTGTCGATCTCCTTCGCTCCCTGGGAGTGGAGGTTGTGAGTTCGGGGAATCTCCTTCAGCTTTTCGCTGCGTGGTCTTCTGAACAGATGGCGGCGCATAGAGAAGCCGCTCGGCAGCTGGGGCAAGTCAAGGACTTGGTTTTTGCCTATATTGCTGAGGTTCTTGCGAAAGGTAAAAAGGTACGGGAGTTTGAAATTCAAGAATATGTGCAGGCCCTTTTTAGGGAACATGGATTGGAAACGGAGCATGGGCCTACTGTGGCTTTCGGTCCCAGCTCTTCTTTGCCTCACTACCGCCCCCGTCCCAAAGCTGACCGCGTGCTTTCCCAAGGAGAGGTGATCTTGCTGGATATGTGGGCCAAGCTGCCGGGTCCTAATCCCTATGCGGACATCACCTGGGTGGCCTTCTGGGGGAGGCCATCCGAGGAGGTGGTTCGGGCTTTTACCGCCGTTTTGGAGGCGCGGGACCGGTGTGTGGATTTTCTTGCTGAGGGTTTGGCTGAGGGGCGCGAGATCCGTGGATGGGAGGTGGATGCGGTTGCGAGGAGGGTCTTGGAGGGGTATGGGTTTGGTTCCTATATACAGCATAGAACCGGACATAGCCTTGGGGTTGCACAGGTTCATGGGGATGCGGTTCACTTCGACGGTTACGAGACACGTGACGATCGGCGGGTGATTCCCAACCTCGGGTATACCGTGGAGCCTGGGGTTTACTTGGGGGACTTCGGTGTAAGAACGGAAATAGATGTGCTCGTGCATCCCGCTTCTGTCGAGATCACCTCACCGGTGCAAAGACAAATAGATGCTCTTTAAAGGAGGTCAAGCAATGGCTGAGCGGAAGGTCCAAGTTGCGGTTGACGTAGGTGGAACATTTACCGATCTGGTGGCTCTGTACGCGGATCCCCACACGGGGACGCAGCGAGTGGTGACGGCCAAAGTCAATACCACGCCCCCAGAGTTCGAAAAAGGGGTGCTTCAGGTGCTTCAAAAAGGGGGGGTTCCCGTGGGGGAAACCGCCCTATTGATACATGGAACCACGGTGGTCATCAACGCCATCACCGAGCGTCGCGGGGTGAAGGTGGGATTAATCACCACCGAGGGGTTTAGAGATGTCCTGGAGATTGCTCGGGGCGATCGTCCTGACTTCTTTAACCTGCTTTACCGTAAGCCTCCACCCTTTGTGCCCCGGTACCTTCGGCGTGAGGTGCCCGGGCGTATGACTTACCGGGGCGAGGAGCGGAGTCCTCTAGATACGAATGTCCTTCCGGGTATCCTAGAGGACTTCAAAAAAGAGGGAGTGGAGGCGGTGGCGGTATGCCTCCTGCATAGTTATGCCAATCCCAGCCATGAGGAAAGGGTTGTTCAGGAAATTCGGCGCCTTTGGCCGGATGTGCCTGTAATTGCTTCGCACGAGATTACACGGGAGTGGAGGGAATACGAACGCACTAGCACTACGGTTCTCTGTGCCTATGTTCTCCCCGTAGCCCAGCGGTACTTAGATCGACTGGGTCAGGGATTGGCGGACCAAGGATTTGGCGGGCAAATCTACATTATGCATTCTAACGGTGGAGTGGAGACCCTCGAGCGGACCAAGCGGGTCCCTATTACCATGATCGAATCCGGACCTGCCGGAGGCTTTTTGGGGGCTGCGGAGCTTGGTCGGCTTCTTGGAGAACCCAACATCTTGGCCTTAGATATAGGTGGGACGACCGCCAAGTGCTCTCTTATCGTGGATGGCCAGGTTCGCATTAAGACAGATTACTGGATTGAAAGAGATCGAAAATCCTCTGGATACCCCATCATGGTTCCCGTGGTAGATGTGGTGGAAATTGGGAACGGAGGTGGAAGTATAGCGTGGGTGGACGATTTCGGCCGCCTGCACGTGGGTCCCCAGTCGGCGGGGGCCCAGCCTGGTCCGGCGGCCTACGGCCGGGGAGGTCAGGACGCTACCACTACCGACGCCAACTTGGCCTTAGGGCGCATTAATCCAAACTATTTCTGTGGCGGCGAAATAGAAGCAGATATGGACGCAGTAAACATGGCCTTGGATCGTCTTTCCGCTCGTTTAGGGATGAAGCGAGAGGAGGTGGCAAGAGGCATTATTCGCTTGGCTAATAACAATATGGTTAACGCACTTAAGCTGGTTTCGGTCAATCGGGGCTACGATCCGCGAGATTTCACCCTTATGGCCTTCGGGGGAGGTGGGGGAATGCACGCTGTGGCCCTTGCGCGGGAGTTGGGGATGCGCAAGGTGATCATTCCTTGGGCGGCGGATGTGTTTTCTGCCTTTGGAATGCTTATGACCGACCTTCGACGCGACTACCTCATTACCCAGCTGATTTCCCTGGACACTCCCCAGGCGGCTTCTCGACTGAGTTGGCTGGCGGAGAGCCTGACCCAGACCGCTTTGGAAGAACTGAAGGCGGAGGGGGTTCCCCTGGAGCGGGCTCGGCTGTTGTATTTCGGACGCATCCGGTACGAGAACCAGGAACATACCGTTGAAATCCCTCTGCCGCCCCCACCTTATCGAGAAGACAGCTTGTCTCAGATTGCCCAAACCTTCCACGAGGCCTACGAGCGGGAGTATACCTACAGGCTTAATGCGCCTTTGGAGTTCGTAACCTTGCACCTTGTGCTCGGTGTGGCTATAGACCGCCTTCAGGTGCCGCGGATGCCCCGTACAGGGCGATCGTTAGAGGAGGCGATGAAGGGTGTCCGGACAGTGGACTTTGATTTAGAGGGTGTACAGCCAGCTAAGATCTACGACGGGCACTCCTTAGAACCGGGTATGGCCTTTGAAGGGCCGGCCATTGTGGAGACCAAAGGAACAACAGTAGTGGTGCATCCTGGATGCCGGGCGGAAGTGGACGATTTCGGCAACCTGCATATTTACCTGTAGGGGGTGGGTAGCATGAGCAAGCTAGACTTCATCACCCTTGAAGTGATCCAGAATTCCTTGCAGGCCATAAGTGATGAGATGTTTGCTGCTATGCGAAAGACGGCCATGAGTCCCATCATCTACGAGGTTCTGGACATGGGAACGGCGGTTACGGACGGCCATGGGAACTTGGCGACCTCCGGGGCGGGTATACCAGCCTTTGTAGCCGTGTTGGACAAAGCCGTCCAAAGGATCATCGAGCTTAACCAGGGCGATATCCGTCCCGGAGATGTGTTTGCTACTAACGACCCCTTCTTCGGCGGGGTTACCCACCTGAACGATGTGGTTCTGGCCATGCCTGTTTTTGTGGAAGGGGAATTGGTGGCTTGGACGGCTAACATTGCCCACTGGAACGATGTGGGCGGTATGGTGCCGGGTTCCATGTCCAACGAGGCTCGGGAAATCTACCAGGAAGGTCTTCGGTTACCGGCTGTTAAAATCGTTGACCAAGGCCAACCTGTGCGGGCAGTGATGGAGATTTTGCGGGCCAACACCCGTCTTCCCGATTTCCTCTGGGGCGATCTCTGGGCAGGTGTGGCAGCGGTTCGCCTTGGAGCTAGGCGCATTCAGGATCTGGCAGCCAAATACGGTAAAGATGTTTTCGTCCAGGCTCTAGATCATTTCATGGCTTATGGGGAGGAAGTTTCTCGTCGGGCTCTAAGGGAACTACCTAAGGGAAAATTTTACCTTGAAGAAGAGCAGGATGATGGCCGGATCTTCAAGGTAACCGTGGAAATACGGGATGATCGCTTTGTGATCGATCTGCGGGATAATCCTGATCAGCACGAAGGCCCCTACAACCTGTGTCGGGACGCAACCCTGATCGCGTGTCAGCTCATCTTTAAAAATGTCACCGATCCCTTTAGTACCGTGGCTAACGCGGGGACCTTCCGTCCTCTAGAAGTGCTAACACGTCCCGGGTCTGTGTTTGACGCTCAGCCGCCCGCAGCCTTTGGCTTTTACTACGAAGTGGAAATTCGGGTATATGATCTTATTTGGCGCTGCTTGGCCCCTTACCTCGAGGATCGGCTTCCTGCCGGGCACTTTGCGTCGATTTGTGGAACCGTTATTGGAGGGCCCCATCCGGATACCGGACGCCACTTCACCATCGTGGAGCCAGAGCTCGGTGGATGGGGAGCCTCCCGGTACTCTGACGGTAACAGCGCTCTATTTAGCGGCTTCCATGGGGAAACTTTCAACTGTCCTGCTGAGGTGGCCGAAGCACGGTATGGGCTCTATGTGGAGCAGCTTCGCCTTAACGACGAACCGGGCGGCGAAGGCTATTTCAGGGGGGGTAAGGGCATTGTGCTTGATTACCGAGTTCGCTCTGATGGGTGCTTCCTAACCATCGGTTATACCCGGAGCAAACAGCGTCCTTGGGCTCTGGCGGGGGGCCGAGAAGGATCCCCGAATTACGTGGAAATATTCCGGAAAGACGGGAGAAGGGAGGTGTATTCCCAAGTTACCGCCCTGCCGCTGAATCGCGGGGATCTGATTCGCATTCACACAGGCAATGGTGGTGGATACGGTGACCCTCGTAGCCGGCCAAGAGAAAAGGTGTTAGAGGATCTGAAGAACGGGTACATCACCTCTGAAATAGCCCGTGAGGTGTACGGCCTGGAGGTTTGACGTAAGGAACCAAGGGTTCTTTTACCGAGGGGTTGTGGATGAAGGACCCCATTACCGTAGAGATCATTGCTGAAGGCCTGGAGGCGGCGGCCCAAGAGATGCTCCTGGTCCTTCAACGAACGGCCATGTCTCCGATTGTGTATGAGGTTCTCGATGCCGGTGCAGGCATCACGGATGCCGCTGGACGGCTGGTGGCCTCCGGGGCGGGCATACCTACTTTTGTGTCCATCATAGACCGCGCTGTGCGTGCGGTCCATGCACATTTCGGAGAGGACATTCGTCCTGGAGATATTTTTCTGACTAACGAACCTTCCCAAGGAGGGGTAACGCACCTTAACGATGTTGCTGCCGTCATGCCTGTCTATGCCATAGGTAGGCGGGTGGCGTGGGTGGGGGTTATTGCCCATTGGAGCGATGTGGGGGGTGGAGTAGCTGGGTCAATGATGGCCGGAGCCGGAGAGCTTTTCCAGGAAGGCATACGTATACCCCCGATCAAGGTGGCCGAAGGTGGCAAAATACTCACCCACGTTTTCCGGTTGCTTAAAACCAATTCCCGTTTACCGGACTTCCTAGAAGGAGACCTTTGGGCCCAGATTGCTGCTCTTAAGGCGGGGGAACGTCGGGTTCGTGAGCTTGCCCGGCGCTATGGTTACGAGGTCTTTGTAGATACGTTGAATGAGATCCTCGAAGCGGGGTACAAGCGGGCCCTTCAGGGCCTGGCCAATTTACCTCAGGGCGACTTTGCCCTGGAGGAAGAACAGGATGACGGCTCTTGCTTTCGCGTTAGGGTGCAAATTCGTCCCGATCAATTTGTGGTGGATCTGAGAGATAATCCTGATCAAATGCCTGGACCGTATAACCTTTATCGCGATGCGACAGAAATAGCTGCTCAAATGATCTTTAAAGCACTTGTTGATCCTAGAAGAGAAGGAGCCAACGCGGGGTTCTTCCGCCCCTTAAAGGTTATAACCCGTCCTGGATCGCTTTTTGATGCGCTACCACCGGCTGCGTGCGGTTTTTATTACGAACTTCGTATGCGGGTGTACGACCTGATTTGGCGTTGTCTCGCCACGCATCACCCTGCGCTCCTGCCTGCAGGTCACTTTGCTACTATAGGAGGTACGGTATTAAGTGGCCGTAATCCCGACAACCAAAAAGCCTATGTCTTGGTGGAGCCCCAGCCTGGAGGCTGGGGGGCTTTCTGGGAGGGAGATGGGGTTTCCACGCTTTTCAGTGCCTTCCATGGAGAAACGTACATTTGCCCCGCTGAAGTTGCCGAGGCTCGCTACGGTTTAGAAGTGGAACGGATGGCCTTGAACGAGGAAAAAGGGGGGGAGGGTCGCTATCGAGGAGGCAAAGGTTTTGTTCGGGTCTACCGTATGCGCGCGGAAGCGCTTCTTACCGTAGGTTTTACCCGCACCCGCATTCCACCTTGGGGGCTTGCAGGAGGGGGTCCGGGGACCCCAAACCGGGTAGAGATAATCTACCCAGACGGATCGATCAGACGGCTGGGTATCGCTAGTGGAGTACGCCTTCCACCGGGGGCACGGGTCCGAATCGTAACCGGCGTTGGGGGAGGTTATGGCGCACGTGGCGATTCAGAAGGCCGGTGAGAAAAGCTAAGAGTTCCCCCCATCACGAGACCGCGGTGCGCCTTCTGGAGGCCGGGCGATATTGCCTGCTGGAGCGAAGGGGGTGTGGAATGTGGGTTGAAGGATTCGGATTCAGGTTTGAAGGAATGTGGCAATGCAACTGAAAGAGTTGCTTGCTCGCATGCCTCTCTTTGATGTGTTAGCAGGGGATCCACATTTGGTCGAGGTGAGCCGCGTGGAGGCGTTGCGCGCAGGAGTGGATCCGCTGCCTGGTACGTTATACCTCGTTGAACGTGAAGATACGTTTTTGGCGTGGATCGACTCAAAACTTGCACCTCCCGCATACCCCGCATAAACCTTCACCCCCTCCCCCCGGCGGCCCCAGACCCAGGGCGTGGAGCTCCCGCAGGATGACCTGCACCACCAGCTCGGGCAAGAGAACCCGAGCTGCCCCCTCCCTGGCCTCCCGCCAGCTCCCCTTCCCCTCCACCCCCACCCAGTGGGCCAGCAGGTAGGCCAGAAGGGAGAGCACCAGAAAGCGGTGCACCCCCAAGGCCGTCCGCTGCCCGAACTGCCCCAGGGAGAACTCGCTCTTCGCAGCCCGGAAGAAGTGCTCCACCGTGAACCGCCTCCTTCCCCAGGTGAGCATGGTCCGGGGCGTGGCGGGAAAGGTGGCCACCACGTACCGCCACTCCCAGCCCCCTTGGGGCAGGGGGTAGCGGTACCAGGCCACCCAGACCGGGAAGGAAAGCCCCCACAGGTAGACCCGGCTCCCCTGCCGCCTGAGGTCCAAAAGCCTTCCCCCTCCCCGCAGCCTCCGGTCCCGCCGCATCCCCACCACCGTTTCCAAGCCCAACCGCCTCACCCCAAAGAGGAACCAGGCCGTACCAAAGGCCGCGTCCGCGGCCACCCGTATCCGGAAGGTCCGGCGCATCCAGAGGGGCAGAGAGGCCAGGAGGCTCAGGGCCAGGAGGGAGAGGCCTTTCTCCCCCTTGCCCCGCCATAGACGGTAGGCCCAGGGGACGCGGAGGTCCCCGTAGACGAGGTAAAGGACCACGAGGTGGAGGCCCCACTTGCCGTGAAAGAAGGAGAGGGGGAGGTGGGGGAAGTGGCCCCGCTTTTCCAGGGTGACCAGGTCCAGGACCACCAGGAGGCGGGGCTTGGGGCCCTTTCTCCGCCTGGCCCGGTCCAGGGCTTTCTGGGCCTCCTCGCGGGCCAGGCGGATGAGGGCGCGGGTGGGCCAGGGGTAGCGGTTGAGGAAGCGGGAGAGGGCGGAGGGGGACTTGGTCTTGCTGTGCTGGGGTCTAGCCTTGCCGTGACCGGTGAGGAAAAGGAACAACAGGGCCTTCAAGGATTCCCGCAGGTGGGGGGTTGGCATGAGGGCCAGGATGGTCCAAAGTAGGGATAGGGCCGCTTGGGTCATGGCCCCCGTCATCAGACGGGAAACCGGCGGCCCCTTTCAAGTGGTCCCCCGAGCATAACTATCCCCAGGGTGCATAAGTGCAAGTTTTGAGTTGACCGACTACACCCCCTTGCGCCAAAGCGCTCTAGGGGTTAAACTAGTAAGTAGAAGCAGGAGTCCGGCGGGGGTCAAAATGTGTCTGGCCATACCTGGTAGGATCGTAGAACTTTTAGATGAGAACGATCACTTTGCGGTGGTCGAGGTAGCCGGTGTACGGCGAAAGATCAATGTGGATCTCCTGAAACAGGAGGGCGTGCGCCCAGGGGACTGGGTGCTTATCCATGTGGGCTTCGCCATGAGTAAGGTAAGCGAAGAGCAGGCCCAAGCGCAGCTGAGGCTCTTGGCCATGCTAGACGAAGAGGCGCAGGCGGTGGAGGAGGTCCAGGGGTACCGCTTCGACTAGGGGGCAAAATGGAGTTGGAGCTTTACGGAAGCTGCACCTTAGACCAAGATGGCTGCGCAACCTGTGGGGATGTGGCTGTGCCGGTGCGGGTGCTGGCCGTGGAAGAGGGGATTGCCTTTGTGGAGGACCGGCTGGGGCAACAGACGCATGTGGCCGTGGACTTCGTTCCCGATGCCCGTCCCGGAGAGGTGATCCTCGTACACGCTGGGGTAGCCATCGGTCGGGCTCAGGAGTAAGGGATGAGATACGTCGATGAGTTCCGGGACCCGGTGTTAATTCAAAAAACTGCTGAAGAAATCCGCCGCTTGATAGATCCAAATCGGCACTATCGTATCATGGAGGTTTGCGGAGGACATACCTTTTCCATCTATCGCTTTGGCCTCCAGGACCTCCTACCTTCCAACGTCGAGCTGGTCCACGGGCCGGGATGTCCGGTTTGCGTCCTGCCCATGGGAAGGGTAGATGACGGGCTTTCCCTTTCGGAAAACCCGAGGGTAATCCTTACGGCCTTCGGGGACATGATGCGCGTCCCGGGTAGGCGAGGCAGTCCCCTGGAGCTTAAGGCAAGGGGGGCGGACATCCGCATGGTGTATTCCCCTTTGGACGCGCTTAAGCTTGCCAGAGAAAATCCCGATCGGGAAGTCGTTTTCTTTGCTATAGGTTTCGAGACCACCGCTCCCTCCACCGCCCTTACCCTTCTTCGGGCACGGGCACTAGGGGTGAAGAACTTCTCGGTCTTCTGCAATCACGTTCTGATTGTTCCTGCTATCCGGGCCATCTTAGACTCGCCGGATATGCGCTTAGATGCTTTTATCGGCCCCGGACACGTTTCCACAGTAATCGGGTGCCGCCCCTATGAGTTTATCGCTCGCGACTACGGCAAGCCGGTAGTGATCTCCGGCTTTGAGCCTTTGGACCTCCTTCAGTCCATCCTCATGATCCTACGTCAGCTCCGGGAGGGAAGGGCTGAGGTAGAAAACCAGTACAAGCGAGCCGTGCCTTGGGAGGGTAATCTGCCCGCGCTTAGGGCAATGGCCGAGGTCTTTGAGCTAAGGCCCTACTTCGAGTGGCGTGGCCTTGGCTTCATTTCGCAGTCTGCGCTTCGGCTTCGGGAGGAATTTGCTCCTTGGGATGCGGAGGTTCGCTTTGCCGTGCCTGGGGTGCGGGTGACCGATCCCAAGGCCGCCCAGTGCGGGGAGGTTCTTAAGGGTGTGCTCAAGCCTCCCCAGTGTAAGCTTTTCGGCAGGGAGTGCACGCCGGAGTACCCCATAGGGGCCCTGATGGTTTCCTCGGAAGGGGCTTGTGCCGCTTACTATCACCACGTCTACCTGCGCCAGGCCGCGGAGGGGGGAACGAATGGCTGAGGCGACCGTGCGTTTCCGCGATACCTGCATCGAGCTCGCCCATGGGGCTGGGGGGAAGGCAAGCCGCCGTCTCATCGAAGGGCTTTTTTTGCCCCTTCTGCGAAACCCAACCCTCGCGGGCCTTGCCGACGCGGCTGTTCTGGAGCTGGAAGGGCTAAGGCTTGCCCTAACAGCAGATAGTTTTGTGGTCAAGCCCATCGTTTTTCCTGGGGGCTCCCTTGGAGAACTGGCGATAAACGGCACGGTGAATGACCTGGCGATGGTGGGGGCAAGACCCCTGGCCCTCCTTGCTACCTTTATCCTTGAAGCTGGACTCGATGCGGGTGTTCTGGAAACTCAGGTAAAAGCCATGGCGCAGGCAGCCGAGAGGGCAGGGGTACCGGTGGTGGGTGGAGACACCAAGGTGGTGGAGCATGGTAAGGCTGATAGCCTCTACGTAACCACCGCAGGTCTGGGATTGGTGGACCCCCGAGTAGATCTCTCCCCAAAAGCAGTCCGCCCCGGGGACCAGGTTCTCCTTTCAGGACCCATTGGGGATCACGGGGTTACCGTGCTCCTTGCCCGAGGAGAACTGGATCTGGAGGCCAGCCTCCGGTCCGATACCCGACCCGTCTGGTTCTTGGTAGAGGCCTTGATTGAGAAAGTCGCCTCCGGTTTACGCTGGATGCGCGACCCCACCCGGGGTGGGGTGGCAACGGCCTTGAACGAGCTCGCCCGAGATGCGGGCGTGGGAGTGGTGCTCTTTGAGGAGGCCCTTCCGGTGAGGGAGGAAGTCCGGGGAGCTTGCGAGATCCTGGGCCTGGACCCGTTACATATCGCCTGCGAAGGCCAGTTCCTGGCCGTGGTGGCTAAGGAACAGGGGGAGGCGGCTCTCGAGGCCCTGCGCCGGACCCCGGGTGGGGAGGAAGCGTGTCTGGTGGGCGAGATACGGGCGGAGCCTGTGGGAACAGTGCAGGTGCTTTCGAGATACGGAGGCAGCCGAGTGGTGGACATGCTGGTGGGAGATCCCCTGCCCCGGATCTGCTAAGAGGATTAAGGCATGGCAGTCAAGGTGGCAGAACTAGCTTCTTGGGTTCGGGAGCGGCTGCTTTTGCGCAACGAGGCCTCTAGGGCTTTCTTCCCAGGGGAAGCCGTCCCCCTTGCCGAGGCCTGTCAGAAGATGGCCGAACGTTTCCTCCGGGGGGGAAGGCTGCTTGCTTTCGGAAAAGGGCCCTACGCTACCGATGCCCAGCATGTTTCCGTGGAGTTTGTCCACCCGGTAATCGTGGGCAAACGGGCCTTGCCTGCCCTAGACCTTTCCTTGGATTTCTGGCCCTGGCTTCAGGCCTTGCTTCGGCCCGAGGATATGGTCATGGGTTTCGGCCCCCCCGAGGGCGACGAAGAGGTTTCCCAAGCCCTGGTTTGGGCCCAGGCTCGTGGAGCCCAAACCTTTGCGTTACCAGGCACCCGAGGCGACTACGCGGTCAGGGCCCCCGCGGCTGATCCCTTTGTCCATCAAGAATTTCTGGAAATTCTCTACCACACCCTGTGGGAAACCGTTCACGTCTTCTTTGAGCACCGGGAGCTCGGGCACGAGGTGGGTCCGGCAGGTTTTCTCTACCCTAGCCTAGGCCAGGTGCGGCAGGACACCCGAGGAGTGGTGGGGGAAGTGGCAGCTTCCATCCAGGCTAAGGCGGAGGAAGACGAGAGGTTACGCATGAAAGTGGCCCAGGAAGAGGCCGAAACCCTGGCCGAACTCATCCAAGCCATAGGCTCGCGGCTTGCCCAAGGAGGCAAGCTCCTCCTTTTCGGCAACGGCGGCTCGGCTACCGATGCCAACGATTTCGCAATCGACTGCGTGAACCCCCCTCCAGGTTGGCGACCCATCCCCGCGGTTTCCTTGGCCCTCGAACCTGCTGTCCTTTCGGCCTTGGCCAACGACGTAGGGGCGGAGGTGATCTTCCTGCGCCAGATCCACGCCCAGGCCCGCCCTGAAGATGTGGCCATCGGCATCTCCACCAGTGGGGGTTCAAAAAACGTGCTTTTGGCCCTAGAAGAGGCCCGCCGACGGGGGCTCCTGACGGTGGCTCTTCTGGGCTACGATGGGGGGGAGGTGGTGCGACAGGGACTGGCCCATTTCCCCCTTGTGGTTCGCTCCGATTACATCCCCCGTATCCAAGAGGTTCAAGCTTCGGTCTACCACGTGATTCGGGAGGGCTTGGAGGTGTACCTTGGTTAAGCTTGAACTCTATGGAACCAAGGGTTGCCCCTATACCGCCGAGCTGCGGGAGGAGCTTGTTTGGCGGGGGATGCCCTTTGTCGAGTACGATGTAGAGGAAGATCTCGAGGCCTTGACGCGCCTCAGGAAGCTCACCGGGGGCTGGATGGTGCCCGTGCTCGTGGAAGACGGCCGGGTGGTTCAAGTGGGTTGGCAGGGCCGCGGGTGTGTGGTGGCGAATCCCGCGGGAAGGGAAGACCAGGGAAAGGCCTAAGGGAGCGGGGCTGGGAATTGGGTCTTAGAGGCCTAGCGGAGGTCCACTTGCGATTGGCCAGGAGTTAAGAGCCAAACCGCAATGAAGCAGGCTTGGCGGGTACGCGTTTGGGGGGTTGTGCAGGGGGTAGGCTTCCGTCCCTTTGTCTACCGACTGGCACAAGCGTACGGGCTGGGGGGCTGGGTAAGGAATGACGAGGAGGCGGTGGAAATGCATGTGGAGGGTCCCTCAGCTGCGCTGGAGGCTTTCTTGGAGGAGCTAAGCAACCACCCTCCGCCGGCTGCTCGGATCGACCGGGTGGTCATAGAGGAAGTGGCGCCAGAGGACCTTGTGGTCTTTGAAATCCGCGAAAGCGCCAAGCGTGACCGTCCAACGGTACGCATCTCCCCCGACCTTGCGGTCTGTCCCGCCTGCCTAAAGGAGCTTTTTGATCCTCAGGACCGGCGTTACCTTTATCCCTACATCAATTGCACAAACTGCGGCCCACGATACTCTATCGTTCTCGCTTTGCCCTACGATCGCTCCCGGACCACCATGAAGGCCTGGGCTTTGTGTCCGGTCTGTGCCCGGGAGTATGAAGACCCCCTGGATCGCCGCTTCCATGCCCAGCCCATCGCCTGCCCAGCGTGTGGGCCCCACTACTTCCTGCGAGAGGAGGATCGGCTGACCCCTGGGGACGAGGCGGCCATAAGGCGTGCGGTTGAACTCCTTAGGGAAGGAAGGATTATCGCGGTAAAGGGTCTGGGAGGATACCATTTGGCCTGCGATGCCGAGAATGCCCAGGCAGTGCAGGCGCTTAGGGAAAGAAAGTACCGCAAGGAAAAACCCTTCGCCCTTATGGTCCGGGACCTCGAGGTAGCCCGGGCTCTGATCGAGCTTACGCCAGAGGCTGAGGCCCTTCTTACTTCTTCGGCCAGGCCCATCCTCCTGGCTCCAGCCCGGCGGGAGCTCCCTGGGGTAGCCCCGGAGAACCGGGATCTGGGTGTGATGCTTCCCTATACTCCCCTTCACTACCTCCTCTTTCACTACGGAGCCCCACCGGTTTTGGTCATGACCAGCGCCAACCGATCGTCCGAACCCATGGCCTATAGGGATGAGGAGGCTCTGGAGAAGCTTTCCGGGATTGCCGATGCTTTTTTGATAGGAGAACGCCCCATTGCCCGGCGGGTGGACGACTCGGTGGTCCGGGTGGGGACGTTTGGCCCCTTGATCCTTCGGCGGGCCCGAGGGTATGCCCCAGCCATGGTGGCTCGGCTTCCCCTTTCCCCACCCCTACTTGCAGTGGGGGCGGACTTAAAAAATGCGGTGACCTTAGTGGTAGAAGGCCAGGCCCTGATGAGCCAGCATCTGGGAGACCTAGAGCATTATGAAGCCTTCATAGCGTTCCAGGAAGCCGTACAAAGCCTTCTTTCCGTATACGAGTTGGAAGCAGAGGAGATCTGGGTAGTTCATGACCTCCACCCGCAGTATCGTTCAACAGCTTATGCCCTAAGCCTTCCGGCCCGCAGCCATTATGCCGTCCAGCATCACCAGGCTCATGTGGCCGCCGTGCTCGCAGAGCGAGGGGCTTTTGAGGAGCGAGTGGTGGGTGTGGCCTTTGACGGCACAGGGTACGGGGAAGACGGCGCCATCTGGGGCGGGGAGTTCTTCCTAGGGAGTCTGGCAGAAGGACTGACGCGCGTGGGCCATCTGCGCTATGCGGCTCTTCCTGGGGGTGATGCCGCTGCTCGCTTCCCTATCCAGGCAGCGGTGGGGTTTCTAGACCAAATCGAAGAGATACCCGATCTAACCCAGCCTCCTTTCTCCTTTTCAGAGCGCTACTTAAAAGCCCGAGAGCTTTTGCGGAGTGGACTACGGGTCTTTCCCACAACCTCGGTGGGACGTCTTTTTGACACGGTGGCCGCTCTTTTGGGATTTACGCGGGAGATTACTTTCGAGGGTCAGGCAGCCATCTGGCTAGAACACCTGGCACGTAAGGCCCTGCCCGTAAAGCCCTATCCGTTCCCCTGGAATGGTAAGGAGTTGGATTTTAGGCCACTTTTGGAAGCGGTTCTCTGGGACCGAGCGCGAGGACGGGACCCTTCGGAGATCGCTCGCGCCTTCCACAGGGGGCTAGCCCAAGGTTTGGTCTCGGCAGCTGTGACCTTGGCCGAAGCCCATGGGGCTATAGCCTTGGTCCTCTCTGGCGGAGTTTTTCAGAACGCTCTTTTACTAGAGGAAATCAGGGCTTTTCTCAGAGAAGTACTGCCTGTTTGGCTACCTCGCGAAGTGCCCCCAAATGATGGGGGTATTAGCCTAGGCCAGGCAGCGCTAGCAACTTTCTCCGAGTCCTTGGCTTTGGATAGGACCTCTTAGGGAGGCTCGCTTAGGATGAGGGTGTGGGCCGGTGGCGGGTCGCCCTCCTCCTCGCCCTGGTGCTGGCCCTGGCCATCCATGCCCCCTGGGCCCTGCAGGGGGTCTACGCTCTGGCCTACCGGGCGTCGGTGGGGCGCCTTCCCCCTTTGCCGCCCCCGGGGGCCGGGGAACGCCTCCTGGTCCTTTCCCCCCATCCCGACGACGAAAGCCTATGCTGCGGGGGGCTTATCAGGGAGGCCCTGGCCCAGGGAGCCGAGGTCTTCGTGGCCTGGCTCACCAGCGGGGACGGGTTTGAGGGGGATGCGGCCCTTTTGGACCGCACCCTAAGGCCGGGCCACGGGGACTACCAGGCCCTGGCCCTGAGGCGGATGGGGGAAGCCCAAAGGGCCGCCCAAGTCCTAGGCCTTCCCCCGGACCACCTCTTCTTCCTCTGCTACCCCGATCGGGGACTCCTTCACTTCCTGGAACGCCGGGCCATCCCCTACACCTCCCCCTACACGGGTCTTGGGGCCGTGACCTACCCAGGCTGCTTCTCCCCAGGAGCCCCCTACACCGGCGAGGCCCTGGAGAAGGACCTGGAGGGGGTTCTGGAAAGGGTACGCCCTACCCTCCTCCTCGCCCCCTCGCCCCTGGACGCCCACCCTGACCACCGAGCGACCGCCTACCTGGCCCTACGGGCCCTGAGACCCGGGGTGCGGGCCCTCTTCTGGATCGTCCACGGGGGGTGGGAGTGGCCCCTGCCCAAGGGGTACCACCCAGGCCTTCCCCTGGAGCCCCCGCCTCGAGGGCGCGGCCTAAGCTGGCGGCGGCTGGACCTGCCGCCCTCCGCCGAGGAGGCCAAGCGCCAGGCCCTCCTGGCCCACCAAAGCCAGCAGCACCTCCTCTCCCGTTTCCTCATGGCCTTCGTACGCCGCAACGAGCTTTATAGCCCCCTCCCCCGCCACCCCCTGCCGGAGTCCGGGCGCTAAGGGGGTGGCGGGATCCGCAAGGCCCTGCCCGGAGGTATAACCGGGTGGGATGGGCGAGGAAGCGGAGGAGATCCGCCTGCTGTGCCGGGTGGCCCTGGGGGACGAGGAGGCCCTCCTTGCCCTCTACCGCCGCTACGCCCCGAGGGTCCACGGGCTCGCCCGGCGCATCCTCCGGGACGGGCACGAGGCCAAGGACGTGGTGCAGGAGACCTTCTTGCGCATCTGGAACCAGGCGGAGCGCTTTGATCCCGCCCTGGGCCGGCCCGCCACCTGGATCCTCACCATCGCCCATAGGCTGGCCCTGAAGCGTCTCAAGGCCCTAAAGCCCCTCTTCTTCGAGGAGGAGGGGGCGGAGGAGCGCGTGGGCGGGGACAACCACCTGGACCGCATCCGGGTGGCCCAGGCCCTGAAGGCCCTATCCCCTGAGGAAAGGAAGCTTCTGGAGCTCGCCTACTTCCAGGGCTACTCCCACAGCGAGCTCGCCCTGCTTTTGGGCTGGCCGCTTGGTACGGTGAAGAGCCGGATCCGCCGCGCCTTGGCCAAGCTGGAGGGGAAGCTCCGATGACCCACCCGGACCCCGACGACCTCCTTCGCCTGGCTTTAGACCTCCTCCCCGAGGGGCAAGGGGCGGGCCTTAGGGCCCATCTGCGCCGCTGCCCCTCCTGCCGCGCCGCCTACCGCGCCTACCTCGAGGCCTTGACCGCCTTAGCCCCTGAGGAGCCCGTGCCCCCTTCCTGGAAGGAGGAGCTAAGGGAGCGCCTCCGCCCAAGGCCCCTCCCGTCGCGCCGGCGGGTTCTGGCCCTCTGGCTTACCGCCCTCCTCCTCACCCTCCTAGGAGCCTTTGGGCTCCGGACCTGGCAGAAGGCGCTTGCCGAGAGGCGCTTTTTCGCCCTGGCGGCCGAGCCTGGGGCCCGGCTCATGCCCCTCCTCGCCCCCTCGGGGCAGCAGACGGGCTGGGCCCTGCGCACCTCGGGGGGTGAGGTGCTTCTCCTCCTCAAGTCCCCCCCGCCCCCGGGCCGGGTCTACCAGGCCTGGCTCCTCCAGGAGGGCCACCGGAAGAGCCTCGGCCTTTCCCCCACCCCCCTCCTGGAGCTGGGTCCCCTGCCCGAGGGAAGCCTGGTGGGGGTCTCGGTGGAGCCCCCCGGGGGTAGCCCCGCCCCCACCACTCCCTCGGTGGGCCGGGCGCGGATCTAGAAGGAGTGGCCATGAAGGGATGGGAAGCGGGACTGATCGCCTCCGGCCTAAGCCTGATCCTGGAAGCCCTGGGACGGAATAAGAGACTGTCGTAAAAGCTTCCCTCCCAGACCTACGCGGCGCTGGCTAGCCGCTTCACCAGCAAGTGTATCATACCCAAGTACATCCAGGCCTCCGTTACCTCGGGATGGTACTCGTAATCCTTCCCCAACCTCCGGTTCCGCCCCATCCAGGCAAAGGTGCGCTCCACCACCCACCGCTTCGGCAAGGGCTTGAACCCCTTCACCCGCTCTGTCTCCGGAAGGGGATGCGCTACCACCTCCAGCTCCAAACCAAGCCCCTCCGCTTCCCTCCGCAAACCCCGGTAGCCAAAGTCCACGTATACCTTCCTCACCCTGGGCCAATGCCTTAGCTCCAACCCCCCTAAAAGAGCCTTCCCGCCCCACCGATCATGCACATTGGCCGGGTGCACGTGGACCCTCAGCAAACGACCCCCGGTGTCCGTCACTATCTGCCGCTGCAAGATTAGCCCTTGCGGGCTGACCCGCCCTTTGACCTGCAAGCTACGGGCTAAGCCCGTGACCTTCGCCCCATCGTGTCCCCGGGGCCCCCTTTTTCACTGGTCTTGACCGACTGGCTATCCCTAACCAGGGCGCTTGGGGAGGCGTAGCGTCTTTCCCGTTCCCGGTCGCGGCGGACCAGGGCCTGGGTCACCCGTTCCCAGACACCTTCTTTCTGCCCCTGGCGGAAGTAGGGGTAGACCGTAGACCAATGGGGCAGGTCAGGAACGTACGTCTGCGGCGTGACGGGGCATAGAGCGCCACTGGATGCCGTTTTCCCGGAGGTAGAGTATGGCGTTGACGATCTCCCTTCAAGGTACGCTCCCGCGTGACCAAGGTACGCTACCGCGTGACCAAGGTACGCTCCCGCGTGACCTAGGCCCTTTTGCCGGGCGGCCGCCTGGTTTAGGGGCGGGAATGAGAGGTTCTAGGCCCACTCGGCATCCGTGAGGTCCCTGGGGTAAGATCTACGTGGAGAAGTCACCCTTCAAGGATAGCCTACTTTTACAACAGCCTCTGACTGGGCCGATAGGGAAACTCGGCGGTCCACCAAGCCGATCCCACAGGTGCTGACGTAAAGGCCATCGGCCTTACCGTGCTCGACCACCTTGGTATCGCCACCAAGAACGCTTACTCCTGCACTTTGGGCCGCTTGCTGGATGGCCTCGAGTTCCGCTTGCAAAGCTTCGCCCGGAAAACCCGCTTCGATGATCAGGCACACAAGCATGGCCACCGGTTGGGCCCCGGAAACCGCAAGGTCGTTAATCGTGCCGTTTACGGCCAGCTCACCAATAGAACCCCCGGAAAGCGCAGGGGCTTGACCACAAAGCTGTCAGCAGTAAAGGCCAGCCGGGTGTCACCTAGCTCGATCAAGGCAGCGGCCTCGAGGCTGGGGTTGCCCAATATGGGAGCAATCAACCCTTCGATCAGGCGGCGACTGGCCTCGCCCCCAGCCCCATGGGGAAGCTCGATACGGGTATCAGTAAATCGCACCTTTCCTGCCCTGGTCTCCTTCATCATCAAGCCGCCTCCACACTCGGGCATGTTGCCCATTCGGAACACGCCCCCAGCTCCACTCCAGGGAGAGCATCACTCGCTGCTTCCCCATCGTTCTTCCAACCGCCCTACCTTCCATACGCCGTAGGAGACCGCCCAGGTCAAGACAAAAAGGCCGACCAACAGATAGCCAAGCCCGCCCAGCTCCAGATTGCCCAACCAATCCCAAAATCGCCCTTTGAACCCCAGTTTTTCCCTCAACACCTGAAGCAATTCGATGCTTCCGATGAGCAGGGCGGCCACCACCGAAAGCCCCGTCACCGTCAGATTGTAGTAGAGCTTGCGCAGCGGAGTGGAAAAAGCCCACCCGTACGCCCGGGTCATGAACACCCCGTCCGCGGTATCCATCAGGCTCATACCCGCCGCAAACAGCAGGGGAAGCGCGAGAATCCCCGGCAAGGACAGGGCTTCCGCGCTTGCGGCGGAAAGGGCCAGCAGGCTGATCTGGCTCGCCGTGTCGAATCCCAGCCCGAAGAGCAGGCCTAGAGGGTAAACGTGCCAGGACTTACTGATAAAACGCCAGAGAGGTTTGGCCAGCCTCGCCACCAGTCCTCGATTCATCAGCAGAACGTCTAGCGATTCCGGCCGGTACTCGCCCCTCCGCAACGCCCTGAAAAGCCGCCAGATATCCACCCAAATTATTAAGTTCAGCAGGGCGATGACCAAGAGAAAAATCCCCGACACCAGGGTGCCGATCAGCCCTCCCACTTCCTGAAAGGCGGGGATCTTCTCCTGCAGCCATTTCGCCGCAATGGCCGTGGCTACCCCCGCAGCGAAGACGACTGTGGAGTGGCCCAAGGAAAAATAAAATCCGACGCCGGAAGGGTTTTGCCCCTGCTGCACCAGTTTTCGCACGGTGTTGTCGATCGCGGCGATATGATCGGCATCAAAGGCGTGACGGAGGCCCAAAGTGTAAGCGAGCAGGCCCATCCCCAGGATGGCCGGATGAGAGCCAGCCTCCACCAAAAGCAACGAAATCGCCAGCAGATGAAGAATACCGACAGCCAACGCGTAAGGCCACCACGGGTAACGGACATCGGCGCCGTTTTGCTTAGTCTGTGCTTCCATCATCGATCACCTCTCCCCCACCGCTTCGCGCAGGTACACGTGTATGGTAATAGGCCGCACAGGCCCCTTCCGACGATCCCATCAGCGCCCCAATGGGGCGCTCTGGTGTACACTCCTTGCCGAACAGTTTGCTCTGATGTGGCTTAAACACGCCTTTGAGCACCTCCCCGCACTGAGCGGCCTTGGGATCGGTAACTCGCACCCCTGCCACCGTGATCGGTAATCCTGCCGGGTATCGCTAGACACATCTCCCTACCTCCTTTTTTCTTTTAAAGATCATTAAAGCTCAGCAACACGTTCGTGTCAAGATGTGCCACTGACCCCAAGACAAGACTTTCGGACACGGTCTCCAAGCACTGATAAAAGTTTTTGATTTTTGAATATTTTGGGCCTCTTACGCTTATTGATTGACCCCTTGACAAGGGGGGAGCCGGTGAGATAGCTTTAGAGAAAGTAAAGGAAGAAAAGGGGGAAATAATATGGTAAGAATCGGTAGCCAGGAAGAGAGCCCCACCTTATCCGTGGCGGAGCAGAAGTTCTTCGAGCGGCTCACGGAGCCGCGCACCCTCGAGCTGCTCAGCCAGCTCCTGGACCGGTTGGAGGATGTGGTCTACCTCCTCGACGTGCTGGAGCAGTTCTTGCGCCGCGGGCCGGAGATCGCCGAGGCGGTCAACGAGGGGGTTGCCCTGCTGCGCAAGGGCCTTGGCGGTACGGCGATGCCCAATGGCTGGACCGATCTGCTCAACGCGTTGCGGCGCCTGAGGCAGGTGGTGGAGTCGCCCCAGGTGCAGGCCCTGTTCCGCGAGAGCGTGCTCGATCCCCGCGCGGTGGCGTTGGTGGGCAAGATGGCCCAGGCCATGATCGAGGCGTCGCAAGAAGCGAAGAAACCCGAACACCGGCGGCTGGGCCTCATGGGGCTCATACGGGCCCTGGGCGATCCCGAGCTGCAGCCGGCGCTGCGCTTCGCCGTAGCCTTCGCCCAGCGCTTCTCCAAGGCACTGGCCGATGCATGAGCTGTCCATCGCCCACAGCCTCGTCGAGCTGGCCACCGAGGAGGCGCGGCGCCGCGGCCTGGGGCGGATCCGGGCGGTCCACCTGCGGGTGGGCGTGCTCTCAGGGGTGGTTACGGAGGCGCTTCGGTTCTGCTTCGACGTGGCCACGGCGGGAACGCCGCTAGAAGGCGCGAGGCTGCTTGTTGACGAGGTGCCTGTGGAGATCTTCTGCCCGCGCTGCGCCGAGCCGAAGATCCTGCCGGCACCCCTGCCGATGGCCTGCCCGGTGTGCGGGACGCGGTCGGCGGAGGTGCTGCGGGGGCGGGAGCTGGAGTTGTACGCCTTGGAGGGGGAGCTGGAGTTGTACGCCTTGGAGGGGAGGGATCACGATGCCGACGCCGAGGATCGTGGAGCTTAGGCAGAACGTGCTGAAGAAGAATGACCTCCTGGCCCGGGAGCTGCGCGGGCGCTTCCGGGAGGCCGGGGTCTACGTGGTGAGCCTGGTCTCCAGTCCGGGCGCCGGGAAGACCACGCTGTTGCGGGAGACGCTGCTCCGCCTGCGGGAGCGCCACCGGGTGGCGGCCCTGGTGGGAGACCTGGCCACGGAGAACGACGCGCGCCAGCTGGGTGAGAGCGGTGCCCCGGCGCGGCAGATCACCACGGGGACCGTGTGCCATCTGGAAGCGGAGATGGTAGAGCGGGCGCTCGAGGGTTGGGACCTGGCCCAGCTCGACCTGCTCTTCATCGAGAACGTGGGGAACTTGGTCTGCCCGGCGAGCTACGACCTCGGCGAGGACCTGCGCGTGCTCCTCTTCTCGGTGACCGAGGGCGAGGACAAGCCGGCCAAGTACCCCACCATCGTCTTAGGCGCAGACCTGGTGCTGCTCACGAAGGTCGACCTGGCGGACGCCTGCGGGTTCGACCGGCAGCGCTTCCACGCCGCGCTGCAGGAGGTCCGGCCCGACGTGCCCGTGCTCGAGGTCTCCGCACGCACCGGCGAAGGGCTCGACGCATGGCTGGCGCGGCTGGAGGAGGGGGTGCGGGCGAAGCAGGGGGCCACGGTGGCGGTTCCTGGGGGCGGTGTGGACGGCGGCGGAGGGAACGCATGGTAGCGCGAGAGAAGACGGAGGTGAGGGGCTATGGCGAACCCCTTGTGGAGGCACGGGAACGCAGGGACGGGAACGCATAGTGGCGTGAGGGGAGAACGGAGGTAGGAGGTAAGGGATTATGGCGAACCTTCTGTGGATGCACGGTGGAGCGTGTAACGGCAATACGCAGTCCTTCCTCAACGCAGAGGAGCCGACGGTGGTCGACCTCGTGACCGACTTCGGCATCAACATCCTGTACCACCACTCTATCTCCATGGAGTTCGGCGAGAGCGCGCGCCGCATCCTGGAGTCGATCCTGAAGGACGAGACTCCCCTGGACATCCTGGTCTTCGAGGGCACGGTGATCCTCGGCCCCAATGGTACCGGTCGCTACAACACGTTCATGGGTCGGCCCATGAAGGATTGGCTCTGGGAGCTGGCCCACAAGGCCCAGTACGTGGTGGCTGTGGGCGATTGCGCCTCCTGGGGAGGCGTCCCCGCCACCCACCCGAACCCCACCGAGTCCATGGGGCTGCAATTCCTGAAGGACAAGCGGGGTGGCTTCCTCGGTCCGGACTTCCGTTCCCGGGCGGGGCTGCCGGTGATCAACATCCCCGGGTGTCCAGCCCACCCCGACTGGGTCACCCAGGTGCTGGTGGCCGTCGCCACCGGGCGGGCGGAGGACGTGGTGCTGGATGAGCTGCAGCGCCCCCAGACCTTCTTCAAGACCTTCACCCAGACGGGCTGCACCCGCGTGCAGTACTTCGAGTGGAAGGAACCCACCGAGGAATTCGGCCAGGGCACGCGCAAGGGTTGCCTCTTCTACGAGTTCGGCTGCCGCGGTCCGCTGACCCATTCGCCCTGCAACCGGATCCTCTGGAACCGGCAGTCGTCCAAGACCCGCGCCGGCATGCCCTGCATCGGCTGCACCGAGCCCCAGTTCCCGCACTACGACCTGGCCCCAGGGACGGTTTTCAAGACCCAGAAGATCTTCGGCGTCATCCCGCGGGAGGTCCCGTTGGGCACCGATCCCTTGAGCTATATGGTTCACGCGGCCGCCGCGCGCGCCGCCGCCCCCAAGTGGGCCCGCGAGGACATGTTCGTGCCCTAGGCCGCGAGGAGCCGGTGCAGCCTGGCTGGGCGAAAGGTGAGAGAAAAGGAGGGTGAGCTCAATGGCGGAAACCAAGGTACAAAAGCGCAGGGAGGAGGTCCACGTACATGCCCTGGGCCGCGTCGAGGGGGACCTTGACGTCCGGGTCCTCATCGAGGACGGGGTCGTGGTGGAGGCCTGGACCCAGGCCACCATGTTCCGGGGCTTCGAGATCATCCTCAAGGGTAAGGATCCCCAGGCGGGCCTCATCGTGACGCCGCGGATCTGCGGCATCTGCGGGGGAAGTCACCTCTACAAGTCGGTCTACGCGCTGGACACGGCCTGGCACACCGAGGTCCCGCCGAACGCCACGCTGATCCGTAACATCGCTCAGGCCTGCGAGACGTTGCAGAGCATCCCGCGCTGGTTCTACGCCCTGTTCGCCATCGGCCTGACGCACAAGAACTACCAGCGTAGCAAGCTCTACGAGGAAGTCTGCCGGCGCTGGGCACCCTTCACGGGGACCAGCTACGAGGTCGGCGTGGTCACCTCGGCCAAGCCCGTGGAGGTCTATGCCATCTTCGGCGGCCAGTGGCCGCACTCCAGCTTCATGGTGCCCGGCGGGGTGATGTGCGGCCCCACGCTCTCGGACATCACGCGCTCCATCTCCATCCTGGAGTACTACCGGACCACGTGGCTCGAGCCCGTGTGGCTGGGCTGCTCGGTAGACCGGTGGCTGGAGAACAAGACCTGGGGTGACGTGCTGAAGTGGCTGGAGGAGAAGCCGGAGCACTTCAACTCGGACCTTGGGCTGTTCATCCGCTACTGCATGGAGATCGGCCTCGACAAGATGGGTGCGGGACCAGGCAGGTACCTGGCCATGGGCACCTACTTCCACCCCGAGAAGTACCGCTTCCCCACCATCGAGGGGCGGAATGCGGCGCTGATCTCCCGCGCCGGCGTGTACGACGGCCGGGAGTTCCACGACTTCGACCAGGCGCGGGTGCGCGAGGACGTGACCTACTCGTACTTCCGCGGCGAGTCGTTCCTGCACCCCTTTGAGGGTGTCACGGAGCCTTTGGATCCCGCCGAGGCCGAGAAGCAGGGCAAGTACACCTGGGCGAAGGCGCCCCGCTACGACCTGCCAGGCGTGGGCCCGATCCCGCTCGAGGCGGGGCCCCTGGCGCGCCAAGTCGTGGCCGGCCGTCCGGGTGCCGAGCCGTGGCAGGACTACGATCCACTCTTCCTCAACATCGTCAAGGAGATCGGACCCAGCGTCATGGTGCGCGTCTTGGCCCGCATGCACGAGGCGGCCAAGTACTACAAGTGGGTGCGCCAGTGGCTCCAGCAGGTCGACCTCGACGAGAAGTTCTACATCAAGCCGAAGGAGTTGCCCGAGGGTCGCGGCTTCGGTGCCACGGAGGCGGCCCGGGGTGCGCTGGCCGACTGGATCGTGCTCAAGGACGGCAAGATCGAGAACTACCAGGTGATCACCCCCACGGCCTGGAACATCGGTCCGCGGGATCGCCGCGGCGAGCGCGGCCCCATCGAGACGGCCATGGTCGGCGCCACCGTGCGGAATCCCGAGGATCCGGTGGAGCTTGCACACATCGCCCAGAGCTACGACTCGTGCTTGGTCTGCACGGTCCACGCCTACGACGCCAAGACGCATAAGGAGCTGGCGCGCTTCATGGTGGGGGGCACCCAGTGACGGGCGGGCACGGGTAAGCGTGCGCCAGCCGGGTGGGGTCAGGGGGGTCGAGGGTGGTCGTCATCATCGGGTGCGGCAATCTGCTGCGGCGCGACGACGGGGTAGGCCCGCTGCTGATTCGCCGCCTCTGGGACCTCGGCCCCCCGCCCGGCGTTCGCCTGGCCGATGGCGGAACGGCAGGCATGGACGTGGCCTTCCAGATCGACGGCGCGACCGAGCTGATCATCGTGGATGCCTGCCGGACGGGCGCGGCGCCGGGCACCGTCTTCGAGGTGCCCGGGGAGGAGCTGGAGACGCCGCCCGTCACCGCCATGAACCTACACGACTTCCGCTGGCAGCACGCCCTGGCCTTCGGCCGCTGGCTCCTCAAGGACCGCTTCCCGGAAAGGGTCACGGTCTTCCTCGTCGAAGCCGAGACCCTGGAGCCCGGCATCGGACTCTCCCCGGCGGTGGAGCAGGCCGTAGAGCGCCTGGCAAGGGAGCTTTTGCGGCGTGTGGGGAACGACGGTGATGCGCGTGGAGATCACACCTAACGGGTACCTGATCCTGCCGGCCGAGGAGGCCGCCCGGTTCCCGGTGGGGACCGCTATCGCGCTGGTGCGCGGCGACGAGCTGTGGCTGATGAGGGTCAGCCACCCTGGGGGAGGGGGCCTCTTGCTCAAGATCCGCAACCCGCGCGGGGACCGGAGCGTGCTGGTGCGGGAGCTGCTGCCGGAGGCTACCGAGCCTGGGGTGCGCGAGGCCTTCTGGGACGAGGAGGCGGGGGCCCTGCGCGTTCCCCTCGCCCCGGCTTCCCAGGCGTCTCGAGGGTAGGTGATCTCGTTGATGCCGGTCTCGATCGCGCTCCGCCCCCAACCCCTCGGCGTCTTCCCGGGGATCGCGGGCTCCTTGCTGCTCCCGCCGGCCCCTGCAGGCGAGGAGGCGCTGGCCGCGCTGATGAAGGGCCGATTGCCCGAACGGTGGCCCGAGGCCTGGCAGTTCTTCGCCCGGGCAGTCGGCGGGTACACCGAGGCCGCGGTGCTGGAGGCCGTGCCGGAGGGTAACGAGGGGATCTTCAACCGCGCGGTCCTCCAGCCCGCCCCTGAGGTGTACACGTGGGCCCGGGAGCGCCTCGGAGGTGAGTACAGGCTGCTTTTGGACGCTGTGGCTTGGCGGGCTGGACTGCGGCCTGAGCCACCCGATGTACCGCCGGAGGTGGACGGCGAGCTGCGGGCCTTCTTGCTGGAATGCAGGGCCCACGCAGCGCTAGAGCGGGGTGCGCGGGAGGAGGGCGCCCTTGCGCTAAAGGCTGCGGCCGAGGCTGCGGAAGCGGTCTCCCCGGTCCTGGCGGCGCGCCTCCTGGGGGAGTGGGCCGCCGTCCGGTACGCGGACGGGGATGCTGGCGAGGAAGTGATCCGCGGCTACCGGGAAGCGCTGGAGCTGCTGGACGGCACGGGCCTGCCCGAGCTCCGTGCGGAGCTTTGGTTCCAGCTGGGTGCGGTCTACCAGTCGCGGGGAGGCGAGGGCGGCAAGGGCGCCCTCCTCGAGGCGGCGCGCTGCTACCAAGAGGCCTTGAAGGTCTTCCGGCGGGATACCTACCCGGAGGCCTATGCCCTGACGCAGATGAACCTGGCCTTGGTGTACCTGGCCATGCCTCAACACGATCGTTCGTGGCTCGTACGCGCCGCGGTGGCCGTGCAGGCGCTGCGAGAAGCGCTGCGCGTCTTCCGCCGCGAGACCCATCCGGAGATGTGGGCCAGCGCCACCTTGAATCTGGCCAACGCGTTGCAACATCTGCCGTCGTCGCATCCCGAGGACAACCTGTGGGAGGCCGTCGCCCTCTACGAGGAGGTCCTGGCGGTGCGACGCCCCGAGGACGACCCCGTGGGCTACGCGCGCGTGCTGGCCAACCAGGGCAATGCCCTCGCCCACCTGGGCGCCCTTTCGCAGGCGGAGTCGCGCCTTCAGGAGGCGCGGCGCCTATTTCTCGAGCATGGTGAGGCCGAGGCCGCCGACGCGGTGGACCGCGTGCTGGCCGAGATCGCGCAGCTCCGCACCGCGGGCGACCGTGCGGTGGGGCGCGTGCAGTCGGGCGGTGCCTCCTGACCGCCCCGCTGGAGGTACTCGGCACGACCTCTAGAAGGAGAGGAGCCATGGAACCCCACGAGCGCCAGATCATGGATCTGCTGATGAACCTGGCCGTCGAATATTTCAGCGAGCGGATCGTCCAACGCAACGAGGGTGCCGGCCGTGCCCTGGGGCGGCTGCGTAACGACCCCGACGGGGAGGGCGTGTGGCTCTCGGAGTTCGTGGAGGCTTTCTTCCGCGAACACCTCCTGGACACGCCCGGGGGCGCTTGCCTGGTGCTCCGGGCTTACGCCCAGCGTCCCTGGAGTCCACCCGAGGCCCTGGCCACGGCAACCACCGTCGGCGACGCGCTGCAGATCATGGCCAAGGCGCTGTTCGCAACCTCGCTGGCCAAAAGGACGGAGGAGGCGCTCGAGCGGGCGCTCGTCTTCGGGGGTGAGTAGGCGTGGCGACCCACGTACAGCAGGAGGAGGACTTCGAGGCCCTAGCCGCCCGGGTGGACCGGGCCCTGGCCGCGGTGCGGGCCCTGCCGGAGGAGGCTCGGGAGAAGGCGCTGGAGCTGAAGGAAGCCATCGAGGCCTTCCACCGATGCGCGCTGCGACGCTTGGTGCGCACCCTCCGGTCCACGGACCACGGCAAGGAGCTGCTGTTGCAGGCGGTGGAGGACCCGTCGGTCTACGCGATGTTCCTCCTGCACGGCATCGTGCGGCAGGACGTGGTCACGCGGGTGGCTGCGGCGCTCGAAGAGGTGCGCCCCTACCTTCGCTCCCACGGCGGTGACGTGGAGCTGGTGAAGGTGGAGGACGGGGTAGCGTACGTCCGCCTCCACGGAGCCTGCCTGGGTTGTTCCCTGTCGGCCCGCACGCTGCAGGACGGCGTGGAGGAGGTCATCAAGGCCCGCGTCCCGGAGATCCAGCGCGTGGCCGTGGTGTCGCAGGGACCGGTCGCAGGATTCGTGCCGCTCGAGGAGATCGGCGACCTGAGTGACCTGAAAGAAAGCGGCTGGGTCGAAGGGCCGCCCGTGGCCGACCTGCCCGAGGGCCGTCCGATTCGCTTCGAGGCCGGGGGGCACGACGTGCTCCTCGTCCGGCTCGGCTCGCGGATCCTGGCCTACCGCAACCAGTGCCCCCACATGGGGAACCCGCTGCATCAGGGTCCGGTGGAGGGTAGCGTGATCACCTGCCCGTGGCACGGCTTCCGGTTCGACCTCGTCTCCGGCGAGTGCCTCACCGTTCCCCACGTGCAGTTGGAGCCCTTCCCCGTACGCGTCCACGGCCAGCGGGTATGGGTACGCCCGAGCTAGCGCTGCAGGCGGAGCCGGTACGCTGGTTGGGGGCGCCTGCTCCCGGCGGCTTGGCGCTACCCCCGGCCCGGGCCGGGCGGCGGACGCTGTACGCTCCGCGGGGGGTCTACCTGGATGACCGGGTGGTAGCGGTGGCCGACAGCGGGAATCACCGCGTGCTCCTCTGGTACGGTTGGCCCAAGGCCGACCACCAGCCGGCGGACGTGGTGCTGGGGCATACGGAGTTCGAGGCGGAAGGGCCGGGCCTCTTGCACCTCCCCACCGCCGTGGCCTTGGTGGAGGGCAGGCTGCTGGTGGCGGACGCCTGGCACCACCGGATCTTGGTCTGGGACGGCTTGCCGGAGGGGAGCGGCCAGCCGCCGGACAGGGTCATCGGGCAGCCCGACCTGCGATCCACGGCCCCCAATGCCGGGGGTAGCACCGGCCCTGCAGGCTTTTACTGGCCCTACGGGTTCGCCTACGTCCACGGCTGGTTCTACGTGGCGGACACGGGCAACCGCCGGGTGCTCGGTTGGCGGGGGGTGCCCGAGGGCTTGCGTCCGGCCGATCTCGTCCTGGGCCAGCCCGATGCCTACAGCGGCGCCGAGAACCGCGGTCGGGGCGTAGGGGCGGACACGTTCCGCTGGCCGCATGCCCTGGCAGGAGACGGGACGACCCTCTACGTGGCCGATGCCGGCAACCACCGGGTACTGGGCTTCACGCCGCCCCCTGAGCAGGACCGGCCGGCGGACCTGGTCCTGGGGCAGGAGGACTTTGACCGGGACTTCGAGCTGCCCCACGTCCCCCAAGGCCCGCGGCGGCTCCGCTTTCCGTACGGTGTGGCCCTGTGCCGCGACTACCTAGCTGTGGCCGACACCGCCAATAACCGGGTACTCCTCTTTCCGGGACCGCCTCGGCGCGGCGTTTACCTCCCTGCCGCCCACGTCATCGGGCAGGCCAATTTCGCCGAGTCGGGCGAGAACCGCTGGCGGGCGGTGGGATGGGACACGCTGTGTTGGCCGTACGGCGTGTGGGGCTACCAAGACCTCCTGGCCGTCGCCGACTCCGGCAACAACCGGGTCATGATCTGGCGGCTGCGTAGGAGTTAGCGGACGTGCGCTCTGCGCCCGTGGGGAGCCTGGGCAGGGTCCGGCTGTTGCGCCTGGCCTTGTTTAAAGCAACGGGGGAGCGCGAGGGGGTTGCAATCATGCGGGCTTGGGGCCTACCTAGAGGCCGTAGAGGGCGGTGTACTTCCCCTCCAGGTAGGTTAGGAAGGGACGCTCGCTTAGGGGAGCCCCGGTAACCCGCTCCACCAAGACCCGGGGCCTATACCGGCTCCCCTCGGCGTGGATCTTCGTGCGGGACCAGTCCAGGAAGGGCCGGAACTCCCCCCGGGCGAACAGGGGCTCGAGGGGGCCGAGCTCCTCTTGGGCCTTGGCGAAGAACTGGGCGGCGTAGAGGTTGCCCAGGGTGTAGGTGGGGAAGTAGCCGAAAAGCCCCCCGGACCAGTGCACGTCCTGCATGACCCCGTCCTTGTAGTCCTTAGGGGCCACCCCCAGGTAGGCCCGGTACTTTTCCGCCCAGGCCCCGGGAAGGTCCTCCAGGGCAAGCTCTCCCCGGAAGAGGGAAAGCTCCAGCTCCAGGCGCACCAGGATATGGAGGTTATAGGTGACCTCGTCCGCCTCCACCCGGATCAGGGAGGGCTCCACGGCGTTGATGGCCCGGTGGAAGTCCTCCAGGGCCACGTCCCGGAGGCTTGGGAAGTGCTCCTTGGCCCGGGGGAAAAACCGCTCCCAAAAACCCAGAGAGCGGCCCACCAGGTTCTCCCAGGTGCGGCTTTGCGACTCGTGAACCCCCAGGGAGACCGCCTCCCCCCTTGGGGTCCCCCAGTGCTCCTTGGGCAGGCCCTGCTCGTAGAGGGCATGGCCCATCTCGTGGAGGGTGCCGAAGATGCCGGCGTTGAAGAAGTCCTCGTAGTAGCGGGTGGTGATGCGCACGTCCCCGGGGCCGATGGAGATGGCAAAGGGATGGGCGGTGGGGTCCAGGCGGCCCGCCTCGAGGTCGTAGCCGAAGGCGGCGAGAAGCTCGAGGGCAAAGGCCCTTTGGGCGTCCTTTGGGTAGTGGCGGTGAAGGATGCCGGTATCCGGCTTCTTCCCACTTCCCAAAATCCGATCCAAAAGCCCCTGAAGCCCCGCCCTAAGCCCGGCGAAAAGCCCCTCCAGCTCCTTAGCCCGCATCCCCGGCTCAAATCCATCCAAAAGGGCGTCGTAGACCTCCCCATAGGGCGGGTCCCCGGGAGCCACGGGAAGGCTATAGAGGATCTCCGCCTTCTCCTTAGTGAGGGCAAACACCCGGCGCAAGTAGGGCAGAAACCCCTGCCAGTCGTCCCTGGGACGGGCTTCCTCCCAGTAGCTTTCCGCCTCGCTTTGCGCCTGGGCCAGCTCCACCATGAGCCGCTCGGGAATGGCCCGGGTGCGCTCGTAGGCCTGCCGCCACTCCCGGACGTTGACCGCCGCATCGGATAGGGGATCCTGCACCAGGTGGGAGCCCTCCACCGCCGAAAGCCATTCCCCAACCCTGGGGTCGGTGGCCCGCTGGTGGAGGAGCCGGGCCAGGGCAGCCATCTGCCTTGCCCGGTGCTCGTGCCCCTTCTTCGGGATCATGGTGCGCTGGTCCCAGGCAGCCAAGGCCCCCAAGGAGGCCAGGTAGGCGGTTTCCCTCTGAAACTCCAAGAGCTTCTGGTAGCTCAAAACTTGCACTTATTCACCGCGGGCATGAGTATGCTTGGGGACCACTTGAAGAGGGCTACTGGTTTCCCCTCTTATGAGGGGTGCCATGAGACCAGTAGCCCTATCCCTACTTTGGACCATCCTGGCCCTCATGCCAACCCCCCACCTGCGGGAATCCTTGAAGGCCCTGTTGTTCCTTTTCCTCACCGGTCACGGCAAGGCTAGACCCCAGCACAGCAAGACCAAGTCCCCCTCCGCCCTCTCCCGCTTCCTCAACCGCTACCCCTGGCCCACCCGCGCCCTCATCCGCCTGGCCCGCGAGGAGGCCCAGAAAGCCCTGGACCGGGCCAGGCGGAGAAAGGGCCCCAAGCCCCGCCTCCTGGTGGTCCTGGACCTGGTCACCCTGGAAAAGCGGGGCCACTTCCCCCACCTCCCCCTCTCCTTCTTTCACGGCAAGTGGGGCCTCCACCTCGTGGTCCTTTACCTCGTCTACGGGGACCTCCGCGTCCCCTGGGCCTACCGTCTATGGCGGGGCAAGGGGGAGAAAGGCCTCTCCCTCCTGGCCCTGAGCCTCCTGGCCTCTCTGCCCCTCTGGATGCGCCGGACCTTCCGGATACGGGTGGCCGCGGACGCGGCTTTTGGTACGGCCTGGTTCCTCTTTGGGGTGAGGCGGTTGGGCTTGGAAACGGTGGTGGGGATGCGGCGGGACCGGAGGCTGCGGGGAGGGGGAAGGCTTTTGGACCTCAGGCGGCAGGGGAGCCGGGTCTACCTGTGGGGGCTTTCCTTCCCGGTCTGGGTGGCCTGGTACCGCTACCCCCTGCCCCAAGGGGGCTGGGAGTGGCGGTACGTGGTGGCCACCTTTCCCGCCACGCCCCGGACCATGCTCACCTGGGGAAGGAGGCGGTTCACGGTAGAGCACTTCTTCCGGGCTGCGAAGAGTGAGTTCTCCCTGGGGCAGTTCGGGCAGCGGACGGCCTTGGGGGTGCACCGCTTTCTGGTGCTCTCCCTTCTGGCCTACCTGCTGGCCCACTGGGTGGGGGTGGAGGGGAAGGGGAGCTGGCGGGAGGCCAGGGAGGGGGCGGCTCGGGTTCTCTTGCCCGAGCTGGTGGTGCAGGTCATCCTGCGGGAGCTCCACGCCCTGGGTCTGGGGCCGCCGGGGGGAGGGGGTGAAGGTTTATGCGGGGTATGCGGGAGGTGCAAGTTTTGA

Protein sequences of DBSCAN-SWA_3

>NC_017273|350853:396075|357367_357946_+|WP_014511305.1|DBSCAN-SWA
MSGEEHLLLEGLGAKIRSRRWQLGLTLRELGRRAGLSAAFLSLVERGHAKPALSSLISLAQALEVSPEFFLSTGLSHGKELVRRSSEIIYFHLDGLPVRYAFLSREIPDRKLDVVLVEIPPGYTSEVWQHPYLGEEFIYVLSGKIKVLLGSRTFCLGPGDSVHFRSDIRHRWANTESDVARVLWVGTPPFWR
>NC_017273|350853:396075|360704_361727_+|WP_014511308.1|DBSCAN-SWA
MGRALFRRLVWSLGVLFGVSLLIFVLARVIPGDPARIALGPMATEEQVEALRRALYLDRPLPLQYVEFLRRVVRGDLGFSTYTKRPVVEDLREYLPATLELVFVSGFIMVALGLPLGIVAAHFRDRWPDALARVLALLGVVTPSFVWAIFLVLIFSYALGWLPVMGRLSEGLSPPPRVTGFLTIDAVLARDWVVFVDALRHLALPALALSLSGLGQAARLARTNLLETFAKPYIELARAYGLSPFAIALKYALRPAMAPTLTIMGLDFAAMLGSAFLVEAVFNWPGLARYMVQATLYKDLNAIVGTALVVAAFFLAVNLLVDLVVVWLNPRLRIQEREGI
>NC_017273|350853:396075|389615_390875_+|WP_014511335.1|DBSCAN-SWA
MPVSIALRPQPLGVFPGIAGSLLLPPAPAGEEALAALMKGRLPERWPEAWQFFARAVGGYTEAAVLEAVPEGNEGIFNRAVLQPAPEVYTWARERLGGEYRLLLDAVAWRAGLRPEPPDVPPEVDGELRAFLLECRAHAALERGAREEGALALKAAAEAAEAVSPVLAARLLGEWAAVRYADGDAGEEVIRGYREALELLDGTGLPELRAELWFQLGAVYQSRGGEGGKGALLEAARCYQEALKVFRRDTYPEAYALTQMNLALVYLAMPQHDRSWLVRAAVAVQALREALRVFRRETHPEMWASATLNLANALQHLPSSHPEDNLWEAVALYEEVLAVRRPEDDPVGYARVLANQGNALAHLGALSQAESRLQEARRLFLEHGEAEAADAVDRVLAEIAQLRTAGDRAVGRVQSGGAS
>NC_017273|350853:396075|388843_389323_+|WP_014511333.1|protease|DBSCAN-SWA
MVVIIGCGNLLRRDDGVGPLLIRRLWDLGPPPGVRLADGGTAGMDVAFQIDGATELIIVDACRTGAAPGTVFEVPGEELETPPVTAMNLHDFRWQHALAFGRWLLKDRFPERVTVFLVEAETLEPGIGLSPAVEQAVERLARELLRRVGNDGDARGDHT
>NC_017273|350853:396075|352149_352707_+|WP_014511303.1|DBSCAN-SWA
MESKSETIRRLYREGKSVSEIAKSLGLSYQRVYTTLRRSGLLKPKGGEPSPSGEPDPEAYARFLQGLEIRSMELMEVHAKLERSPKGKLSFRMGLEAFGPEPREGGFTAGLALGLDFQDEEGPFGFLRLRVRAGYATPLFPDEPLFRAFRERNLIVHLWPYLRLYADFLTAQMGLPRLVLPAWKV
>NC_017273|350853:396075|382874_383909_-|WP_014511327.1|DBSCAN-SWA
MEAQTKQNGADVRYPWWPYALAVGILHLLAISLLLVEAGSHPAILGMGLLAYTLGLRHAFDADHIAAIDNTVRKLVQQGQNPSGVGFYFSLGHSTVVFAAGVATAIAAKWLQEKIPAFQEVGGLIGTLVSGIFLLVIALLNLIIWVDIWRLFRALRRGEYRPESLDVLLMNRGLVARLAKPLWRFISKSWHVYPLGLLFGLGFDTASQISLLALSAASAEALSLPGILALPLLFAAGMSLMDTADGVFMTRAYGWAFSTPLRKLYYNLTVTGLSVVAALLIGSIELLQVLREKLGFKGRFWDWLGNLELGGLGYLLVGLFVLTWAVSYGVWKVGRLEERWGSSE
>NC_017273|350853:396075|369454_371029_+|WP_014511315.1|DBSCAN-SWA
MKDPITVEIIAEGLEAAAQEMLLVLQRTAMSPIVYEVLDAGAGITDAAGRLVASGAGIPTFVSIIDRAVRAVHAHFGEDIRPGDIFLTNEPSQGGVTHLNDVAAVMPVYAIGRRVAWVGVIAHWSDVGGGVAGSMMAGAGELFQEGIRIPPIKVAEGGKILTHVFRLLKTNSRLPDFLEGDLWAQIAALKAGERRVRELARRYGYEVFVDTLNEILEAGYKRALQGLANLPQGDFALEEEQDDGSCFRVRVQIRPDQFVVDLRDNPDQMPGPYNLYRDATEIAAQMIFKALVDPRREGANAGFFRPLKVITRPGSLFDALPPAACGFYYELRMRVYDLIWRCLATHHPALLPAGHFATIGGTVLSGRNPDNQKAYVLVEPQPGGWGAFWEGDGVSTLFSAFHGETYICPAEVAEARYGLEVERMALNEEKGGEGRYRGGKGFVRVYRMRAEALLTVGFTRTRIPPWGLAGGGPGTPNRVEIIYPDGSIRRLGIASGVRLPPGARVRIVTGVGGGYGARGDSEGR
>NC_017273|350853:396075|387161_388790_+|WP_014511332.1|DBSCAN-SWA
MAETKVQKRREEVHVHALGRVEGDLDVRVLIEDGVVVEAWTQATMFRGFEIILKGKDPQAGLIVTPRICGICGGSHLYKSVYALDTAWHTEVPPNATLIRNIAQACETLQSIPRWFYALFAIGLTHKNYQRSKLYEEVCRRWAPFTGTSYEVGVVTSAKPVEVYAIFGGQWPHSSFMVPGGVMCGPTLSDITRSISILEYYRTTWLEPVWLGCSVDRWLENKTWGDVLKWLEEKPEHFNSDLGLFIRYCMEIGLDKMGAGPGRYLAMGTYFHPEKYRFPTIEGRNAALISRAGVYDGREFHDFDQARVREDVTYSYFRGESFLHPFEGVTEPLDPAEAEKQGKYTWAKAPRYDLPGVGPIPLEAGPLARQVVAGRPGAEPWQDYDPLFLNIVKEIGPSVMVRVLARMHEAAKYYKWVRQWLQQVDLDEKFYIKPKELPEGRGFGATEAARGALADWIVLKDGKIENYQVITPTAWNIGPRDRRGERGPIETAMVGATVRNPEDPVELAHIAQSYDSCLVCTVHAYDAKTHKELARFMVGGTQ
>NC_017273|350853:396075|352759_356014_+|WP_014511304.1|DBSCAN-SWA
MALSNREIVGKGLDLLRSGLRPFVEREYRRVYGEEWVREAGEVLKGDRASLQDPDAQALLKLMDYRWNEVFDEKLGRWGRTLVKELLEFRNRWAHQGAFSFEDAHRALDSMTRLLEMIAAEEAQETVRMARELLRRRFEEEAKREAERAVKQSLAVVPQGLKPWREVVTPHPDVASGRYSEAEFAADLAQVHRGEAGEEYGNPLEFYRRTHLTSGLKRLLLNALKRLAGEGGDPVVELQTAFGGGKTHSMLALYHLFGGAVDPGEVPGLEDLLAQAGVARVPLARRAVFVGTAFSPARPHPKPEGVVVRTLWGEIAYQLGGVEGYRMLEEEDRTGVAPGSDVLKELFDRFSPALVLIDEWVAFLRNLYGEEGLPAGTFDQNLTFAQALTEAAKRSPRALVVASLPASDAEVGGGGGREALLRLQNVFGRLESVWQPATQDETYEIVRRRLFQPLSAEGYRVRDAVVREYVRYYREHRGEFPSEVLEPRYEERMRLAYPIHPELFDRLYEDWATLEGFQRTRGVLRLLASVVYTLWVRGDTSPLILPGGLPLDADGPRYELVRHLSRHQEGFDQVIDSDIDGPNAKAFALEKERPSLGRHQAARRAARAVFLATAPAGAAPTGKPRGVEGVRVKLGVAHPGESPALFTEALKALSERLVYFHAEGDRYWFETRPSLNRMAQDRAAAVSREEALMELEERLRAWAKGRPALFQGVHAAPAGSGEVADEPSLRLVVLSPRTPYAKGGSEAERWAREVLEGRGRAPRRYRNTLLFLAPEAVLVPDLEEAARQYLAWRSIWEDRESLNLGAADVRQVESRLRQAEDTLRLRLEEAYRHLLVFHQPDPKAPDLEVDALRLLGSGNPLERAASKAQNEGLVLVRWHPEFLGETLARYGFWEVAEPEGVLPLRRLWEDLASYLYLPRLKDEGVLLATVAQGVKEGRFGYAERLEGGVPKGVVLGEEVAPSLGGYLLKPEVAARFLKEKTGEDVPPPPDGEGDDEKVPVPPPPRPSRPRRFYLKKTLRMESLLPEVRALAEEVLLHLYKEGGVRLEVVLEAHAEAPEGFPEDLERVLKENSRVLGAEASFEEV
>NC_017273|350853:396075|363516_364509_+|WP_155983637.1|DBSCAN-SWA
MSFMRRCPVADILLEVRDLTKEFAVGRKRVRALNGVSLGLEEGEILAVVGESGSGKTTLANLVLGIEMPTYGDILYRGTPLKTPRPLHMRRRLQYVQQNPWTTLNPRRTVFQSVALPLAVHKLTPPRLWRERVAELLHLVGLGPEFLDRYPHALSGGQRQRVAIARALAAQPEMVILDEPTSALDVSVQARVLGLLLEIQARFSLSYLFISHDLAVVRNFARRILVLYRGQVMETGPTEVVFRNPVHPYTRLLLASVPVVSEEEAALRPSWPWDAQDRLGPGEGCPFSSRCPWAQELCWRERPSLVPIQKSHLVACHFAELFVEEVSHHG
>NC_017273|350853:396075|361731_362577_+|WP_014511309.1|DBSCAN-SWA
MRRESLRRFWYHFGRNPLSLLGLSVVTLVVVGALGAPWIAPYPEHAGRFVNFAEAGQPPSLHHLLGTDTFGRDLFSRILFGYRISLALGVVVLGIAVPLGVTLGLWAGYIGGGIATWIMRLSDVFVAIPPLVLAMAVLGVAEPSLTNAMMALTLMWWPWYTRMIYNQVRSLRLEGYVVAAQIIGASATHIMFREILPNTLPNILTKAALDMGFVILIGASLSFLGLGVQPPTPDLGTMVAEGARYLPDLWWLAVFPGLAILFVVLGFNLLADGLRDALGEG
>NC_017273|350853:396075|394974_396075_+|WP_041444900.1|transposase|DBSCAN-SWA
MRPVALSLLWTILALMPTPHLRESLKALLFLFLTGHGKARPQHSKTKSPSALSRFLNRYPWPTRALIRLAREEAQKALDRARRRKGPKPRLLVVLDLVTLEKRGHFPHLPLSFFHGKWGLHLVVLYLVYGDLRVPWAYRLWRGKGEKGLSLLALSLLASLPLWMRRTFRIRVAADAAFGTAWFLFGVRRLGLETVVGMRRDRRLRGGGRLLDLRRQGSRVYLWGLSFPVWVAWYRYPLPQGGWEWRYVVATFPATPRTMLTWGRRRFTVEHFFRAAKSEFSLGQFGQRTALGVHRFLVLSLLAYLLAHWVGVEGKGSWREAREGAARVLLPELVVQVILRELHALGLGPPGGGGEGLCGVCGRCKF
>NC_017273|350853:396075|380080_380596_+|WP_014511325.1|DBSCAN-SWA
MGEEAEEIRLLCRVALGDEEALLALYRRYAPRVHGLARRILRDGHEAKDVVQETFLRIWNQAERFDPALGRPATWILTIAHRLALKRLKALKPLFFEEEGAEERVGGDNHLDRIRVAQALKALSPEERKLLELAYFQGYSHSELALLLGWPLGTVKSRIRRALAKLEGKLR
>NC_017273|350853:396075|376447_376708_+|WP_014511322.1|DBSCAN-SWA
MVKLELYGTKGCPYTAELREELVWRGMPFVEYDVEEDLEALTRLRKLTGGWMVPVLVEDGRVVQVGWQGRGCVVANPAGREDQGKA
>NC_017273|350853:396075|392141_393248_+|WP_014511338.1|DBSCAN-SWA
MGTPELALQAEPVRWLGAPAPGGLALPPARAGRRTLYAPRGVYLDDRVVAVADSGNHRVLLWYGWPKADHQPADVVLGHTEFEAEGPGLLHLPTAVALVEGRLLVADAWHHRILVWDGLPEGSGQPPDRVIGQPDLRSTAPNAGGSTGPAGFYWPYGFAYVHGWFYVADTGNRRVLGWRGVPEGLRPADLVLGQPDAYSGAENRGRGVGADTFRWPHALAGDGTTLYVADAGNHRVLGFTPPPEQDRPADLVLGQEDFDRDFELPHVPQGPRRLRFPYGVALCRDYLAVADTANNRVLLFPGPPRRGVYLPAAHVIGQANFAESGENRWRAVGWDTLCWPYGVWGYQDLLAVADSGNNRVMIWRLRRS
>NC_017273|350853:396075|384914_385319_+|WP_014511329.1|DBSCAN-SWA
MHELSIAHSLVELATEEARRRGLGRIRAVHLRVGVLSGVVTEALRFCFDVATAGTPLEGARLLVDEVPVEIFCPRCAEPKILPAPLPMACPVCGTRSAEVLRGRELELYALEGELELYALEGRDHDADAEDRGA
>NC_017273|350853:396075|386128_387100_+|WP_014511331.1|DBSCAN-SWA
MANLLWMHGGACNGNTQSFLNAEEPTVVDLVTDFGINILYHHSISMEFGESARRILESILKDETPLDILVFEGTVILGPNGTGRYNTFMGRPMKDWLWELAHKAQYVVAVGDCASWGGVPATHPNPTESMGLQFLKDKRGGFLGPDFRSRAGLPVINIPGCPAHPDWVTQVLVAVATGRAEDVVLDELQRPQTFFKTFTQTGCTRVQYFEWKEPTEEFGQGTRKGCLFYEFGCRGPLTHSPCNRILWNRQSSKTRAGMPCIGCTEPQFPHYDLAPGTVFKTQKIFGVIPREVPLGTDPLSYMVHAAAARAAAPKWAREDMFVP
>NC_017273|350853:396075|371330_372431_-|WP_041445286.1|transposase|DBSCAN-SWA
MTQAALSLLWTILALMPTPHLRESLKALLFLFLTGHGKARPQHSKTKSPSALSRFLNRYPWPTRALIRLAREEAQKALDRARRRKGPKPRLLVVLDLVTLEKRGHFPHLPLSFFHGKWGLHLVVLYLVYGDLRVPWAYRLWRGKGEKGLSLLALSLLASLPLWMRRTFRIRVAADAAFGTAWFLFGVRRLGLETVVGMRRDRRLRGGGRLLDLRRQGSRVYLWGLSFPVWVAWYRYPLPQGGWEWRYVVATFPATPRTMLTWGRRRFTVEHFFRAAKSEFSLGQFGQRTALGVHRFLVLSLLAYLLAHWVGVEGKGSWREAREGAARVLLPELVVQVILRELHALGLGPPGGGGEGLCGVCGRCKF
>NC_017273|350853:396075|372603_372873_+|WP_014511317.1|DBSCAN-SWA
MCLAIPGRIVELLDENDHFAVVEVAGVRRKINVDLLKQEGVRPGDWVLIHVGFAMSKVSEEQAQAQLRLLAMLDEEAQAVEEVQGYRFD
>NC_017273|350853:396075|389300_389603_+|WP_014511334.1|DBSCAN-SWA
MRVEITPNGYLILPAEEAARFPVGTAIALVRGDELWLMRVSHPGGGGLLLKIRNPRGDRSVLVRELLPEATEPGVREAFWDEEAGALRVPLAPASQASRG
>NC_017273|350853:396075|382006_382090_-|WP_155983650.1|transposase|DBSCAN-SWA
MVNAILYLRENGIQWRSMPRHAADVRS
>NC_017273|350853:396075|380592_381225_+|WP_014511326.1|DBSCAN-SWA
MTHPDPDDLLRLALDLLPEGQGAGLRAHLRRCPSCRAAYRAYLEALTALAPEEPVPPSWKEELRERLRPRPLPSRRRVLALWLTALLLTLLGAFGLRTWQKALAERRFFALAAEPGARLMPLLAPSGQQTGWALRTSGGEVLLLLKSPPPPGRVYQAWLLQEGHRKSLGLSPTPLLELGPLPEGSLVGVSVEPPGGSPAPTTPSVGRARI
>NC_017273|350853:396075|367760_369416_+|WP_014511314.1|DBSCAN-SWA
MSKLDFITLEVIQNSLQAISDEMFAAMRKTAMSPIIYEVLDMGTAVTDGHGNLATSGAGIPAFVAVLDKAVQRIIELNQGDIRPGDVFATNDPFFGGVTHLNDVVLAMPVFVEGELVAWTANIAHWNDVGGMVPGSMSNEAREIYQEGLRLPAVKIVDQGQPVRAVMEILRANTRLPDFLWGDLWAGVAAVRLGARRIQDLAAKYGKDVFVQALDHFMAYGEEVSRRALRELPKGKFYLEEEQDDGRIFKVTVEIRDDRFVIDLRDNPDQHEGPYNLCRDATLIACQLIFKNVTDPFSTVANAGTFRPLEVLTRPGSVFDAQPPAAFGFYYEVEIRVYDLIWRCLAPYLEDRLPAGHFASICGTVIGGPHPDTGRHFTIVEPELGGWGASRYSDGNSALFSGFHGETFNCPAEVAEARYGLYVEQLRLNDEPGGEGYFRGGKGIVLDYRVRSDGCFLTIGYTRSKQRPWALAGGREGSPNYVEIFRKDGRREVYSQVTALPLNRGDLIRIHTGNGGGYGDPRSRPREKVLEDLKNGYITSEIAREVYGLEV
>NC_017273|350853:396075|365675_367748_+|WP_014511313.1|DBSCAN-SWA
MAERKVQVAVDVGGTFTDLVALYADPHTGTQRVVTAKVNTTPPEFEKGVLQVLQKGGVPVGETALLIHGTTVVINAITERRGVKVGLITTEGFRDVLEIARGDRPDFFNLLYRKPPPFVPRYLRREVPGRMTYRGEERSPLDTNVLPGILEDFKKEGVEAVAVCLLHSYANPSHEERVVQEIRRLWPDVPVIASHEITREWREYERTSTTVLCAYVLPVAQRYLDRLGQGLADQGFGGQIYIMHSNGGVETLERTKRVPITMIESGPAGGFLGAAELGRLLGEPNILALDIGGTTAKCSLIVDGQVRIKTDYWIERDRKSSGYPIMVPVVDVVEIGNGGGSIAWVDDFGRLHVGPQSAGAQPGPAAYGRGGQDATTTDANLALGRINPNYFCGGEIEADMDAVNMALDRLSARLGMKREEVARGIIRLANNNMVNALKLVSVNRGYDPRDFTLMAFGGGGGMHAVALARELGMRKVIIPWAADVFSAFGMLMTDLRRDYLITQLISLDTPQAASRLSWLAESLTQTALEELKAEGVPLERARLLYFGRIRYENQEHTVEIPLPPPPYREDSLSQIAQTFHEAYEREYTYRLNAPLEFVTLHLVLGVAIDRLQVPRMPRTGRSLEEAMKGVRTVDFDLEGVQPAKIYDGHSLEPGMAFEGPAIVETKGTTVVVHPGCRAEVDDFGNLHIYL
>NC_017273|350853:396075|376789_379063_+|WP_014511323.1|DBSCAN-SWA
MKQAWRVRVWGVVQGVGFRPFVYRLAQAYGLGGWVRNDEEAVEMHVEGPSAALEAFLEELSNHPPPAARIDRVVIEEVAPEDLVVFEIRESAKRDRPTVRISPDLAVCPACLKELFDPQDRRYLYPYINCTNCGPRYSIVLALPYDRSRTTMKAWALCPVCAREYEDPLDRRFHAQPIACPACGPHYFLREEDRLTPGDEAAIRRAVELLREGRIIAVKGLGGYHLACDAENAQAVQALRERKYRKEKPFALMVRDLEVARALIELTPEAEALLTSSARPILLAPARRELPGVAPENRDLGVMLPYTPLHYLLFHYGAPPVLVMTSANRSSEPMAYRDEEALEKLSGIADAFLIGERPIARRVDDSVVRVGTFGPLILRRARGYAPAMVARLPLSPPLLAVGADLKNAVTLVVEGQALMSQHLGDLEHYEAFIAFQEAVQSLLSVYELEAEEIWVVHDLHPQYRSTAYALSLPARSHYAVQHHQAHVAAVLAERGAFEERVVGVAFDGTGYGEDGAIWGGEFFLGSLAEGLTRVGHLRYAALPGGDAAARFPIQAAVGFLDQIEEIPDLTQPPFSFSERYLKARELLRSGLRVFPTTSVGRLFDTVAALLGFTREITFEGQAAIWLEHLARKALPVKPYPFPWNGKELDFRPLLEAVLWDRARGRDPSEIARAFHRGLAQGLVSAAVTLAEAHGAIALVLSGGVFQNALLLEEIRAFLREVLPVWLPREVPPNDGGISLGQAALATFSESLALDRTS
>NC_017273|350853:396075|359062_360691_+|WP_155983636.1|DBSCAN-SWA
MWGLGRRRGGEAMRLWKLGMALVFIGVLSLALGQEKILRLDEVAVGELDPAKATDYADSILMFNVYDTLVWPDARGKLQPHLAQRWTVSQDGLTYTFNLRPGVRFHDGAEVTAQDVVFSLNRMVAINQGYAYLFRGWVKEARAIDRYTVRFTLSEPYAPFLATLVRLPIINRNLVLKNLRPGPFGEFGDYGQAFLSRADAGSGAYRIASHDPQALTVMAKYPAYFLGFAQGAPDLVRLRYSLEPATVRTLMVRREHEVTSQWLPPEIYRALAQQGLDLVTEGGNTIFFLKLNNKRPPTDDVHFRKAMALAFDYDALLDILRVTDRVRMGKKARGPLPEGFPGFDAALPLPKRDLAAAKAELAKSKYDPRSMRVEIAWVAEVPLEEKIALLFQQNMAELGIQVDVVKVPWALMTERATKPETTPHVTSVYVSATFPDPDSLLYSMYHSKAAGTWLSMSWLQDKRVDELLDLGRRTVDEARRREIYVQLQRYLVENQVDIYGYEQLEVFAKQPYVSIPTLESPEKQVAGVMAGNWLFRLMKVRR
>NC_017273|350853:396075|374229_375264_+|WP_014511320.1|DBSCAN-SWA
MAEATVRFRDTCIELAHGAGGKASRRLIEGLFLPLLRNPTLAGLADAAVLELEGLRLALTADSFVVKPIVFPGGSLGELAINGTVNDLAMVGARPLALLATFILEAGLDAGVLETQVKAMAQAAERAGVPVVGGDTKVVEHGKADSLYVTTAGLGLVDPRVDLSPKAVRPGDQVLLSGPIGDHGVTVLLARGELDLEASLRSDTRPVWFLVEALIEKVASGLRWMRDPTRGGVATALNELARDAGVGVVLFEEALPVREEVRGACEILGLDPLHIACEGQFLAVVAKEQGEAALEALRRTPGGEEACLVGEIRAEPVGTVQVLSRYGGSRVVDMLVGDPLPRIC
>NC_017273|350853:396075|379122_380031_+|WP_126170838.1|DBSCAN-SWA
MLALAIHAPWALQGVYALAYRASVGRLPPLPPPGAGERLLVLSPHPDDESLCCGGLIREALAQGAEVFVAWLTSGDGFEGDAALLDRTLRPGHGDYQALALRRMGEAQRAAQVLGLPPDHLFFLCYPDRGLLHFLERRAIPYTSPYTGLGAVTYPGCFSPGAPYTGEALEKDLEGVLERVRPTLLLAPSPLDAHPDHRATAYLALRALRPGVRALFWIVHGGWEWPLPKGYHPGLPLEPPPRGRGLSWRRLDLPPSAEEAKRQALLAHQSQQHLLSRFLMAFVRRNELYSPLPRHPLPESGR
>NC_017273|350853:396075|364501_365662_+|WP_014511312.1|DBSCAN-SWA
MDRLKEVQQLLEKEGLDGWLLYDFRGQNPLALSVLGIVHTLLTRRWFVWVPTVGKPQALVHVIEKDNLPWTYPKRVYASRESLVEELSGLLGGARRVAMEYSPLGDNPYLSRVDAGTVDLLRSLGVEVVSSGNLLQLFAAWSSEQMAAHREAARQLGQVKDLVFAYIAEVLAKGKKVREFEIQEYVQALFREHGLETEHGPTVAFGPSSSLPHYRPRPKADRVLSQGEVILLDMWAKLPGPNPYADITWVAFWGRPSEEVVRAFTAVLEARDRCVDFLAEGLAEGREIRGWEVDAVARRVLEGYGFGSYIQHRTGHSLGVAQVHGDAVHFDGYETRDDRRVIPNLGYTVEPGVYLGDFGVRTEIDVLVHPASVEITSPVQRQIDAL
>NC_017273|350853:396075|351723_352146_+|WP_014511082.1|DBSCAN-SWA
MGNNINFSDYFRESMKDPEARRLYREVLDEELSWLLSYLREERRLSQKEVAERLGVSRGRVSQLETSAGLSMSLESLARYAQALGLSLRLEFADERGEVLARFSLAADEPVAETTNPAWENAGAGWEPASGKASWASWAA
>NC_017273|350853:396075|372881_373109_+|WP_014511318.1|DBSCAN-SWA
MELELYGSCTLDQDGCATCGDVAVPVRVLAVEEGIAFVEDRLGQQTHVAVDFVPDARPGEVILVHAGVAIGRAQE
>NC_017273|350853:396075|362582_363548_+|WP_014511310.1|DBSCAN-SWA
MSLLEVKQLNLSLRTHTGLAHILKDVSLRVEAGERVALVGETGCGKSLTLKAILGLLEGKGLVVSGKVLFEDEEILGTPRILRLRGVQIGFIPQDPAASLNPTFSIADQLLAVVRRVRRNLPKEKAWALIKEALVEVAVPDPDRVLASYPFQLSGGLCQRVLIAMALVNRPKLVLADEPGTALDVTVQAQTLRAMRHLTEKSGSSVILVTHNLGVVREFADRVYVMYAGTIVEHGPVKSVFQTPRHPYTRALLDSVPRLTGGGLPQGLDGHIPDYTSPPKGCRFRPRCAFARPECAEEQPLRQVAEGHEVACVLYAEVPRG
>NC_017273|350853:396075|375276_376455_+|WP_014511321.1|DBSCAN-SWA
MAVKVAELASWVRERLLLRNEASRAFFPGEAVPLAEACQKMAERFLRGGRLLAFGKGPYATDAQHVSVEFVHPVIVGKRALPALDLSLDFWPWLQALLRPEDMVMGFGPPEGDEEVSQALVWAQARGAQTFALPGTRGDYAVRAPAADPFVHQEFLEILYHTLWETVHVFFEHRELGHEVGPAGFLYPSLGQVRQDTRGVVGEVAASIQAKAEEDERLRMKVAQEEAETLAELIQAIGSRLAQGGKLLLFGNGGSATDANDFAIDCVNPPPGWRPIPAVSLALEPAVLSALANDVGAEVIFLRQIHAQARPEDVAIGISTSGGSKNVLLALEEARRRGLLTVALLGYDGGEVVRQGLAHFPLVVRSDYIPRIQEVQASVYHVIREGLEVYLG
>NC_017273|350853:396075|393365_394898_-|WP_014511339.1|DBSCAN-SWA
MQVLSYQKLLEFQRETAYLASLGALAAWDQRTMIPKKGHEHRARQMAALARLLHQRATDPRVGEWLSAVEGSHLVQDPLSDAAVNVREWRQAYERTRAIPERLMVELAQAQSEAESYWEEARPRDDWQGFLPYLRRVFALTKEKAEILYSLPVAPGDPPYGEVYDALLDGFEPGMRAKELEGLFAGLRAGLQGLLDRILGSGKKPDTGILHRHYPKDAQRAFALELLAAFGYDLEAGRLDPTAHPFAISIGPGDVRITTRYYEDFFNAGIFGTLHEMGHALYEQGLPKEHWGTPRGEAVSLGVHESQSRTWENLVGRSLGFWERFFPRAKEHFPSLRDVALEDFHRAINAVEPSLIRVEADEVTYNLHILVRLELELSLFRGELALEDLPGAWAEKYRAYLGVAPKDYKDGVMQDVHWSGGLFGYFPTYTLGNLYAAQFFAKAQEELGPLEPLFARGEFRPFLDWSRTKIHAEGSRYRPRVLVERVTGAPLSERPFLTYLEGKYTALYGL
>NC_017273|350853:396075|350853_351585_+|WP_041445191.1|transposase|DBSCAN-SWA
MRPCWRGFPGNWRPTWPPCLPLKRMALQRVEARKGRSRDVPRPLPREPLPGRFPPHLMDTTGLAYRSKDRLLRFRRGKEVRRVRGHARLLALMRWDRERRLLWPWGGVVGEGYAPDPRLGGEVLRRFPPSGGWLLADAGFDGKEVWGVLGEAGVRPVIRLRGGGEAREEARVRAREGWDPEVYRFRGVVEGVFGGMKTRLGGGYLWERKPWTAMARALLELIAYGLRVLLSLLPPPPGYKAIY
>NC_017273|350853:396075|384388_384922_+|WP_014511328.1|DBSCAN-SWA
MVRIGSQEESPTLSVAEQKFFERLTEPRTLELLSQLLDRLEDVVYLLDVLEQFLRRGPEIAEAVNEGVALLRKGLGGTAMPNGWTDLLNALRRLRQVVESPQVQALFRESVLDPRAVALVGKMAQAMIEASQEAKKPEHRRLGLMGLIRALGDPELQPALRFAVAFAQRFSKALADA
>NC_017273|350853:396075|373112_374237_+|WP_014511319.1|DBSCAN-SWA
MRYVDEFRDPVLIQKTAEEIRRLIDPNRHYRIMEVCGGHTFSIYRFGLQDLLPSNVELVHGPGCPVCVLPMGRVDDGLSLSENPRVILTAFGDMMRVPGRRGSPLELKARGADIRMVYSPLDALKLARENPDREVVFFAIGFETTAPSTALTLLRARALGVKNFSVFCNHVLIVPAIRAILDSPDMRLDAFIGPGHVSTVIGCRPYEFIARDYGKPVVISGFEPLDLLQSILMILRQLREGRAEVENQYKRAVPWEGNLPALRAMAEVFELRPYFEWRGLGFISQSALRLREEFAPWDAEVRFAVPGVRVTDPKAAQCGEVLKGVLKPPQCKLFGRECTPEYPIGALMVSSEGACAAYYHHVYLRQAAEGGTNG
>NC_017273|350853:396075|385290_386013_+|WP_014511330.1|DBSCAN-SWA
MPTPRIVELRQNVLKKNDLLARELRGRFREAGVYVVSLVSSPGAGKTTLLRETLLRLRERHRVAALVGDLATENDARQLGESGAPARQITTGTVCHLEAEMVERALEGWDLAQLDLLFIENVGNLVCPASYDLGEDLRVLLFSVTEGEDKPAKYPTIVLGADLVLLTKVDLADACGFDRQRFHAALQEVRPDVPVLEVSARTGEGLDAWLARLEEGVRAKQGATVAVPGGGVDGGGGNAW
>NC_017273|350853:396075|391302_392160_+|WP_014511337.1|DBSCAN-SWA
MATHVQQEEDFEALAARVDRALAAVRALPEEAREKALELKEAIEAFHRCALRRLVRTLRSTDHGKELLLQAVEDPSVYAMFLLHGIVRQDVVTRVAAALEEVRPYLRSHGGDVELVKVEDGVAYVRLHGACLGCSLSARTLQDGVEEVIKARVPEIQRVAVVSQGPVAGFVPLEEIGDLSDLKESGWVEGPPVADLPEGRPIRFEAGGHDVLLVRLGSRILAYRNQCPHMGNPLHQGPVEGSVITCPWHGFRFDLVSGECLTVPHVQLEPFPVRVHGQRVWVRPS
>NC_017273|350853:396075|390922_391300_+|WP_014511336.1|DBSCAN-SWA
MEPHERQIMDLLMNLAVEYFSERIVQRNEGAGRALGRLRNDPDGEGVWLSEFVEAFFREHLLDTPGGACLVLRAYAQRPWSPPEALATATTVGDALQIMAKALFATSLAKRTEEALERALVFGGE
>NC_017273|350853:396075|357950_358307_+|WP_081466168.1|DBSCAN-SWA
MEKLALAWPDPEGVKELGTFLLPSGERVILGTARFPQGRLIPERGFSLHQGSELSLLLEGSLEVEVEGRETGDIIRAGEVTFIPAGVPHRAKVLQPTLLVWVWIETGREEDGQADIVD
>NC_017273|350853:396075|381337_381787_-|WP_155983638.1|transposase|DBSCAN-SWA
MQVKGRVSPQGLILQRQIVTDTGGRLLRVHVHPANVHDRWGGKALLGGLELRHWPRVRKVYVDFGYRGLRREAEGLGLELEVVAHPLPETERVKGFKPLPKRWVVERTFAWMGRNRRLGKDYEYHPEVTEAWMYLGMIHLLVKRLASAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041445191.1|350853_351585_+|transposase	transposase	NA	NA	NA	NA
WP_014511082.1|351723_352146_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014511303.1|352149_352707_+	hypothetical protein	NA	NA	NA	NA
WP_014511304.1|352759_356014_+	ATP-binding protein	NA	NA	NA	NA
WP_014511305.1|357367_357946_+	cupin domain-containing protein	NA	NA	NA	NA
WP_081466168.1|357950_358307_+	cupin domain-containing protein	NA	NA	NA	NA
WP_155983636.1|359062_360691_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014511308.1|360704_361727_+	ABC transporter permease	NA	NA	NA	NA
WP_014511309.1|361731_362577_+	ABC transporter permease	NA	NA	NA	NA
WP_014511310.1|362582_363548_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.5e-14	31.9
WP_155983637.1|363516_364509_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	6.5e-18	32.3
WP_014511312.1|364501_365662_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_014511313.1|365675_367748_+	hydantoinase/oxoprolinase family protein	NA	NA	NA	NA
WP_014511314.1|367760_369416_+	hydantoinase B/oxoprolinase family protein	NA	NA	NA	NA
WP_014511315.1|369454_371029_+	hydantoinase B/oxoprolinase family protein	NA	NA	NA	NA
WP_041445286.1|371330_372431_-|transposase	transposase	NA	NA	NA	NA
WP_014511317.1|372603_372873_+	HypC/HybG/HupF family hydrogenase formation chaperone	NA	NA	NA	NA
WP_014511318.1|372881_373109_+	HypC/HybG/HupF family hydrogenase formation chaperone	NA	NA	NA	NA
WP_014511319.1|373112_374237_+	hydrogenase formation protein HypD	NA	NA	NA	NA
WP_014511320.1|374229_375264_+	hydrogenase expression/formation protein HypE	NA	NA	NA	NA
WP_014511321.1|375276_376455_+	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	1.4e-11	31.9
WP_014511322.1|376447_376708_+	glutaredoxin	NA	NA	NA	NA
WP_014511323.1|376789_379063_+	carbamoyltransferase HypF	NA	NA	NA	NA
WP_126170838.1|379122_380031_+	PIG-L family deacetylase	NA	NA	NA	NA
WP_014511325.1|380080_380596_+	sigma-70 family RNA polymerase sigma factor	A0A0F6TH34	Sinorhizobium_phage	1.1e-05	26.3
WP_014511326.1|380592_381225_+	anti-sigma K factor	NA	NA	NA	NA
WP_155983638.1|381337_381787_-|transposase	transposase	NA	NA	NA	NA
WP_155983650.1|382006_382090_-|transposase	transposase	NA	NA	NA	NA
WP_014511327.1|382874_383909_-	HoxN/HupN/NixA family nickel/cobalt transporter	NA	NA	NA	NA
WP_014511328.1|384388_384922_+	DUF1641 domain-containing protein	NA	NA	NA	NA
WP_014511329.1|384914_385319_+	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_014511330.1|385290_386013_+	hydrogenase nickel incorporation protein HypB	NA	NA	NA	NA
WP_014511331.1|386128_387100_+	hydrogenase	NA	NA	NA	NA
WP_014511332.1|387161_388790_+	nickel-dependent hydrogenase large subunit	NA	NA	NA	NA
WP_014511333.1|388843_389323_+|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_014511334.1|389300_389603_+	hypothetical protein	NA	NA	NA	NA
WP_014511335.1|389615_390875_+	hypothetical protein	NA	NA	NA	NA
WP_014511336.1|390922_391300_+	hypothetical protein	NA	NA	NA	NA
WP_014511337.1|391302_392160_+	Rieske 2Fe-2S domain-containing protein	A0A0K0KWE8	Prochlorococcus_phage	7.1e-05	34.9
WP_014511338.1|392141_393248_+	hypothetical protein	NA	NA	NA	NA
WP_014511339.1|393365_394898_-	carboxypeptidase M32	NA	NA	NA	NA
WP_041444900.1|394974_396075_+|transposase	transposase	NA	NA	NA	NA