CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017537	Listeria monocytogenes M7, complete sequence	3 crisprs	DinG,WYL,casR,cas6,cas8b2,cas7,cas5,cas3,cas2,DEDDh,RT,csa3	3	10	5	8

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017537_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017537_1

510180-510764

Orphan

Consensus_repeat	Method
GATGTAAGTAATTTTGATACNAGTTCAGTAACTNATATG	CRT

7 spacers

The CRISPR arrays of NC_017537_1

>merge|NC_017537|1|510180-510764|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATGTGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTGGATGTAAGTCATTTTGATACGAGTTCAGTAACTAATATGTCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTGGATGTAAGCAACCTTGATACGAGTTCAGTAACTAATATGTATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTGGATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATGTATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTAGATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATGGTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTGGATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATGCGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTAGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGGCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTTGATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

>NC_017537|1|1|510180-510764|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATG	TGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTG
GATGTAAGTCATTTTGATACGAGTTCAGTAACTAATATG	TCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTG
GATGTAAGCAACCTTGATACGAGTTCAGTAACTAATATG	TATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTG
GATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATG	TATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTA
GATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATG	GTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTG
GATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATG	CGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTA
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	GCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTT
GATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017537.1\|WP_012581916.1\|507732_509271_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NC_017537.1\|WP_012581910.1\|513390_514353_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NC_017537.1\|WP_003725208.1\|516994_518098_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl\|CDD\|237717
NC_017537.1\|WP_012581921.1\|500343_501291_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NC_017537.1\|WP_012581920.1\|501447_503043_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NC_017537.1\|WP_012581922.1\|499190_500339_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NC_017537.1\|WP_012581909.1\|518187_518667_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NC_017537.1\|WP_003721271.1\|518824_519190_+\|heme-oxygenase-IsdG	unknown	unknown	gnl\|CDD\|183970
NC_017537.1\|WP_012581919.1\|503177_504461_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|271377
NC_017537.1\|WP_012581913.1\|512150_512636_+\|hypothetical-protein	unknown	unknown	unknown
NC_017537.1\|WP_012581917.1\|505554_507105_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NC_017537.1\|WP_012581918.1\|504461_505562_+\|DUF917-domain-containing-protein	unknown	unknown	gnl\|CDD\|226065
NC_017537.1\|WP_003728986.1\|515143_516844_+\|oleate-hydratase	unknown	unknown	gnl\|CDD\|227060
NC_017537.1\|WP_012581925.1\|495455_496142_-\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|226146
NC_017537.1\|WP_012581923.1\|497034_499194_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
NC_017537.1\|WP_012581924.1\|496162_496918_-\|DUF4866-family-protein	unknown	unknown	gnl\|CDD\|379782
NC_017537.1\|WP_012581914.1\|511657_512131_+\|hypothetical-protein	unknown	unknown	unknown
NC_017537.1\|WP_003735640.1\|514473_515034_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379534
NC_017537.1\|WP_003733328.1\|513044_513311_+\|hypothetical-protein	unknown	unknown	unknown
NC_017537.1\|WP_012581912.1\|512663_512969_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|273478

Protein	Function_ID	Function_description	E-value
NC_017537.1\|WP_012581916.1\|507732_509271_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	5.93123e-19
NC_017537.1\|WP_003725208.1\|516994_518098_+\|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl\|CDD\|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	0
NC_017537.1\|WP_012581921.1\|500343_501291_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	3.27176e-102
NC_017537.1\|WP_012581920.1\|501447_503043_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.08161e-58
NC_017537.1\|WP_012581922.1\|499190_500339_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	3.60668e-54
NC_017537.1\|WP_012581909.1\|518187_518667_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	9.93072e-45
NC_017537.1\|WP_003721271.1\|518824_519190_+\|heme-oxygenase-IsdG	gnl\|CDD\|183970	PRK13316, PRK13316, heme oxygenase IsdG.	3.55164e-70
NC_017537.1\|WP_012581919.1\|503177_504461_+\|cytosine-permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	8.96878e-96
NC_017537.1\|WP_012581910.1\|513390_514353_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.28639e-44
NC_017537.1\|WP_012581917.1\|505554_507105_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.05299e-105
NC_017537.1\|WP_012581918.1\|504461_505562_+\|DUF917-domain-containing-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
NC_017537.1\|WP_003728986.1\|515143_516844_+\|oleate-hydratase	gnl\|CDD\|227060	COG4716, COG4716, Myosin-crossreactive antigen [Function unknown].	0
NC_017537.1\|WP_012581925.1\|495455_496142_-\|DUF1275-domain-containing-protein	gnl\|CDD\|226146	COG3619, COG3619, Predicted membrane protein [Function unknown].	5.77882e-69
NC_017537.1\|WP_012581923.1\|497034_499194_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	3.24483e-28
NC_017537.1\|WP_012581924.1\|496162_496918_-\|DUF4866-family-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	1.89267e-121
NC_017537.1\|WP_003735640.1\|514473_515034_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	3.74116e-25
NC_017537.1\|WP_012581912.1\|512663_512969_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	1.28025e-05

>NC_017537.1|WP_012581916.1|507732_509271_+|helix-turn-helix-domain-containing-protein
MREYLDSKSQKKVALLEKIFYAENHTCTQEELLNELNITYPTLISTIKTINFDIERFGYKEFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLSSFPNLQALAKKVHVSYSGIKKEIKELNEELSERNLYISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVRYDEITDLLESCPKEIYRADSIDKAMMIHYYVAMHLLRDRMNCHIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASERVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIVYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>NC_017537.1|WP_012581917.1|505554_507105_+|hydantoinase/oxoprolinase-family-protein
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIEHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGMAEIGNPELVAHIPTDFAEKAYKKIADMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDADQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>NC_017537.1|WP_012581918.1|504461_505562_+|DUF917-domain-containing-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPDEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTDSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>NC_017537.1|WP_012581919.1|503177_504461_+|cytosine-permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGIQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVSGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>NC_017537.1|WP_012581920.1|501447_503043_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKIDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERVIEASKQMGEHELVQLHLDERDFYTARKPIFQDGMQAMHLFMMKEKGALTADVAMQVTEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFALMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKSLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>NC_017537.1|WP_012581921.1|500343_501291_-|MoxR-family-ATPase
MSIEPSIKINEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>NC_017537.1|WP_012581922.1|499190_500339_-|DUF58-domain-containing-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRSFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKTLTIYPTYFPDVLEKISESSPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>NC_017537.1|WP_012581923.1|497034_499194_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHVVMIIIVSGIYYAKGGILAGNWLGSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHILVILLLAVFVFSSLMLPKKAPIFPDPIPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDKFPIQLTEQTTGVTNTAEISFASSSDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVAKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDTKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTPENTPEQNNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVALLALAIIFRRRIRSYLLLRSLKNSPEFGKTYHRLMKLLASYGYVRESSETLRHFGTRVDAELTTTEFSRLTKMYEAQVYSNNLTEKVITAEETQLVQQVIARLTK
>NC_017537.1|WP_012581924.1|496162_496918_-|DUF4866-family-protein
MTTIFPKEQNVTPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETAIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>NC_017537.1|WP_012581925.1|495455_496142_-|DUF1275-domain-containing-protein
MARSRQISESIGLGLLLALAGGFMDAYSYIERGQVFANAQTGNILLFGINLSEGNWAIAIQYFWPVVSFTVGIAISEVIHRRDIRRLHWRQLSVLIEVVILIGVAFIPLDHNLIANSLISFVCGIQVESFRKMHGRGIATTMCIGNLRSATQNLCDYFEYKEKQYLRNSLLYFTVILSFIIGAVVGNFFIQLFAQYAILVCAFIQFIAFMMMFIDRESKIIIKKLPTK
>NC_017537.1|WP_012581914.1|511657_512131_+|hypothetical-protein
MKKKKVVVISLLLLLVSVIGISSYFLFKDKINLLDVDPSAVEWNGKKQKDTSGEENTIAIPGFEKVTLYANETKQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKPLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>NC_017537.1|WP_012581913.1|512150_512636_+|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGATSDVITSSFKSNNSVVTMANPVIGSFSGYAMDETEVSKIQIGSPQGDKKAGAYQTTLTFTAAFK
>NC_017537.1|WP_012581912.1|512663_512969_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKRKLVLAMVLISFCGMFFLSPDRVQASHTVVEVLISEDDLDVSEENVQEIPKKELAASSDKDNKQHTLPKAGDTVTNYTLLGLVLILIWLIMQRKRKKKE
>NC_017537.1|WP_003733328.1|513044_513311_+|hypothetical-protein
MARIEYGEEIQKSLLVLYSRGSTIDSICKEYGIPRYEFHKWMKLHDSDKLETKEVETFLQIRELKQQKNKLEEEILFLNEAINLLESP
>NC_017537.1|WP_012581910.1|513390_514353_-|HD-domain-containing-protein
MKMTDPLYGTFEIEPVLAELIQSPLVSRLAHVHQGGSSYLVNPLWDLSRLDHSIGVMLFIRKFGGSLEEQIAGLLHDVSHTAFSHVVDYALDFEEEDYHEQIFEDFVKTSTIPAILEKYGYSFEGIFDDISKWKILEQEAPELCADRIDYTLQDLYRHGKISLAEVEEFLQALVMVDGRLYLANIALAEWFVAQYYSEVIDYFYDPLNVYSYEILAEAMRIAFQQETITNADLRLTDAELLAKLNANSDAWEKIQLLESPHLEENEVDFTYHHKKKMRLINPSVLVDGRLIPADELSGKVREMNDWASEKSKHGSYIKVT
>NC_017537.1|WP_003735640.1|514473_515034_+|TetR/AcrR-family-transcriptional-regulator
MAESLITKKAIAGGLMELCQHKRFEKISIADITNICGLNRQTFYYHFTDKYDLLTWTYENDFFHCLADGITLENWDKHVLKMLESIKENADFYKNTVSADASILSFCFSKLTNSLFMDLFEKIDTNGAVNEADRVFYAEFFSYGCSGVLIKWITRGFKEAPETIANQLFRLAKDTEFLANSMYREN
>NC_017537.1|WP_003728986.1|515143_516844_+|oleate-hydratase
MKNKKRTLVALTGAAIGTGIAAKKISEQKAAEKERAVDEAIKARYYGDKQVYFVGGGIASLAGAVYLIRDANFDGKNIHIIEGMHILGGSNDGAGSVEHGFVCRGGRMLNEETYENFWDLFSSIPSLDMPNFSVTEEILNFDHLHPTHAQARLVDKDRNILDAHSMGFNNNDRMLMTKLLATPEEKLDNLTIRDWFDEHFFETNFWYMWQTTFAFQKWSSLFEFRRYMNRMMLEFSRIDTLEGVTRTPLNQYESLILPLKTFLDKHHVDFTINQTVEDIDFKDAPGITATALHLSDGSTIELGPDDDVIMTNACMTDSATLGDMNTPAPKPEEKPISGELWYKVAQKKPNLGNPEPFFGHEEETNWQSFTVTCHGDKLLKRIERFTGNIPGSGALMTFKDSNWLMSTVVAAQPHFKAQDANTTIFWGYGLYPDRVGDFVKKPMKECTGEEILYELMCHLNWQDDFEEIKADIINVIPCYMPYIDAQFEPRAMSDRPAVVPEGSTNFAMISQFVEIPKDMVFTEEYSVRAARIAVYTLLDIDKKICPVTPHNRDPKVLAKATQTMFR
>NC_017537.1|WP_003725208.1|516994_518098_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
>NC_017537.1|WP_012581909.1|518187_518667_+|AraC-family-transcriptional-regulator
MEVEIVERNAFTAVGKKRTFSVENDAQKEKISQFWQEANTNGDAERINELAEFATIDGILGVCQMNGDKMDYYIAIESELTPPEDMEKLTIPASKWAIFKSVGPLPNAIQKVWEYIYGEWFQTSNYTHGNAPELEVYTEGDTTAADYYSEVWIPVVEKD
>NC_017537.1|WP_003721271.1|518824_519190_+|heme-oxygenase-IsdG
MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK

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Crispr_ID: NC_017537_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017537_2

541639-542057

Unclear

I-A

Consensus_repeat	Method
GTTTTAGTTACTTAATGTGAAATGTAAAT	PILER-CR
GTTTTAGTTACTTAATGTGAAATGTAAAT	CRISPRCasFinder
GTTTTAGTTACTTAATGTGAAATGTAAATN	CRT

6 spacers

cas6

The CRISPR arrays of NC_017537_2

>merge|NC_017537|2|541639-542057|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGTTACTTAATGTGAAATGTAAATTTTCCCCAACTGCGCCCTGTTTTAATTGCTTAACGTTTTAGTTACTTAATGTGAAATGTAAATATATACTGGCAAGTTTATCTTGATGTTTCTGACTATCGTTTTAGTTACTTAATGTGAAATGTAAATCGTATATTTAATTTTCGGCATATAATCCCATCAATGTTTTAGTTACTTAATGTGAAATGTAAATCTGTTCATTTATTTTTCAGTCCTATGTTCATTGCCTCGTTTTAGTTACTTAATGTGAAATGTAAATCCGGAAGATTTAGCAGTGGATCCATTTCCGTTTGAAGTTTTAGTTACTTAATGTGAAATGTAAATAATCGTCACGATGGGAAAGTCGTTGATAGCGCGCCACGTTTTAATTACTTATCATAAATATAAATC

>NC_017537|2|1|541639-541991|PILER-CR
GTTTTAGTTACTTAATGTGAAATGTAAAT	TTTCCCCAACTGCGCCCTGTTTTAATTGCTTAAC
GTTTTAGTTACTTAATGTGAAATGTAAAT	ATATACTGGCAAGTTTATCTTGATGTTTCTGACTATC
GTTTTAGTTACTTAATGTGAAATGTAAAT	CGTATATTTAATTTTCGGCATATAATCCCATCAAT
GTTTTAGTTACTTAATGTGAAATGTAAAT	CTGTTCATTTATTTTTCAGTCCTATGTTCATTGCCTC
GTTTTAGTTACTTAATGTGAAATGTAAAT	CCGGAAGATTTAGCAGTGGATCCATTTCCGTTTGAA
GTTTTAGTTACTTAATGTGAAATGTAAAT

>NC_017537|2|1|541639-541991|CRISPRCasFinder
GTTTTAGTTACTTAATGTGAAATGTAAAT	TTTCCCCAACTGCGCCCTGTTTTAATTGCTTAAC
GTTTTAGTTACTTAATGTGAAATGTAAAT	ATATACTGGCAAGTTTATCTTGATGTTTCTGACTATC
GTTTTAGTTACTTAATGTGAAATGTAAAT	CGTATATTTAATTTTCGGCATATAATCCCATCAAT
GTTTTAGTTACTTAATGTGAAATGTAAAT	CTGTTCATTTATTTTTCAGTCCTATGTTCATTGCCTC
GTTTTAGTTACTTAATGTGAAATGTAAAT	CCGGAAGATTTAGCAGTGGATCCATTTCCGTTTGAA
GTTTTAGTTACTTAATGTGAAATGTAAAT

>NC_017537|2|2|541639-542057|CRT
GTTTTAGTTACTTAATGTGAAATGTAAAT	TTTCCCCAACTGCGCCCTGTTTTAATTGCTTAAC
GTTTTAGTTACTTAATGTGAAATGTAAAT	ATATACTGGCAAGTTTATCTTGATGTTTCTGACTATC
GTTTTAGTTACTTAATGTGAAATGTAAAT	CGTATATTTAATTTTCGGCATATAATCCCATCAAT
GTTTTAGTTACTTAATGTGAAATGTAAAT	CTGTTCATTTATTTTTCAGTCCTATGTTCATTGCCTC
GTTTTAGTTACTTAATGTGAAATGTAAAT	CCGGAAGATTTAGCAGTGGATCCATTTCCGTTTGAA
GTTTTAGTTACTTAATGTGAAATGTAAAT	AATCGTCACGATGGGAAAGTCGTTGATAGCGCGCCAC
GTTTTAATTACTTATCATAAATATAAATC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017537.1\|WP_003725719.1\|539055_540327_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NC_017537.1\|WP_041176481.1\|544250_544610_-\|Lin0512-family-protein	unknown	unknown	gnl\|CDD\|131113
NC_017537.1\|WP_012581891.1\|543545_544226_+\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153212
NC_017537.1\|WP_012581888.1\|547875_549306_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NC_017537.1\|WP_012581896.1\|532692_533343_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
NC_017537.1\|WP_003725715.1\|536629_537028_+\|hypothetical-protein	unknown	unknown	unknown
NC_017537.1\|WP_003730559.1\|537685_538732_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
NC_017537.1\|WP_012581892.1\|542785_543322_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|213029
NC_017537.1\|WP_003725716.1\|537038_537689_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
NC_017537.1\|WP_012581895.1\|533451_535512_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_017537.1\|WP_012581886.1\|550594_551317_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_017537.1\|WP_003725724.1\|544616_545075_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NC_017537.1\|WP_003721289.1\|536145_536613_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NC_017537.1\|WP_003727301.1\|538747_539041_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
NC_017537.1\|WP_012581893.1\|542133_542775_-\|hypothetical-protein	unknown	unknown	unknown
NC_017537.1\|WP_012581889.1\|545455_547297_+\|LapB-repeat-containing-protein	unknown	unknown	gnl\|CDD\|380190
NC_017537.1\|WP_012581887.1\|549426_550242_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NC_017537.1\|WP_012581894.1\|535515_536118_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
NC_017537.1\|WP_003721301.1\|547397_547829_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NC_017537.1\|WP_003725720.1\|540466_541402_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929

Protein	Function_ID	Function_description	E-value
NC_017537.1\|WP_003725719.1\|539055_540327_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	1.81393e-177
NC_017537.1\|WP_041176481.1\|544250_544610_-\|Lin0512-family-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	2.27468e-65
NC_017537.1\|WP_012581888.1\|547875_549306_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	1.55499e-102
NC_017537.1\|WP_012581896.1\|532692_533343_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	6.25172e-64
NC_017537.1\|WP_012581889.1\|545455_547297_+\|LapB-repeat-containing-protein	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	1.15539e-120
NC_017537.1\|WP_012581891.1\|543545_544226_+\|type-1-glutamine-amidotransferase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	1.54211e-60
NC_017537.1\|WP_012581892.1\|542785_543322_-\|hypothetical-protein	gnl\|CDD\|213029	cd11375, Peptidase_M54, Peptidase family M54, also called archaemetzincins or archaelysins. Peptidase M54 (archaemetzincin or archaelysin) is a zinc-dependent aminopeptidase that contains the consensus zinc-binding sequence HEXXHXXGXXH/D and a conserved Met residue at the active site, and is thus classified as a metzincin. Archaemetzincins, first identified in archaea, are also found in bacteria and eukaryotes, including two human members, archaemetzincin-1 and -2 (AMZ1 and AMZ2). AMZ1 is mainly found in the liver and heart while AMZ2 is primarily expressed in testis and heart; both have been reported to degrade synthetic substrates and peptides. The Peptidase M54 family contains an extended metzincin concensus sequence of HEXXHXXGX3CX4CXMX17CXXC such that a second zinc ion is bound to four cysteines, thus resembling a zinc finger. Phylogenetic analysis of this family reveals a complex evolutionary process involving a series of lateral gene transfer, gene loss and genetic duplication events.	0.000170261
NC_017537.1\|WP_003725716.1\|537038_537689_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	5.23266e-109
NC_017537.1\|WP_012581895.1\|533451_535512_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	3.82523e-80
NC_017537.1\|WP_012581886.1\|550594_551317_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.40258e-33
NC_017537.1\|WP_003725724.1\|544616_545075_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	9.49445e-13
NC_017537.1\|WP_003721289.1\|536145_536613_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	3.45565e-37
NC_017537.1\|WP_003727301.1\|538747_539041_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.39912e-27
NC_017537.1\|WP_003730559.1\|537685_538732_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
NC_017537.1\|WP_012581887.1\|549426_550242_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.85144e-49
NC_017537.1\|WP_012581894.1\|535515_536118_+\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	8.84641e-75
NC_017537.1\|WP_003721301.1\|547397_547829_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NC_017537.1\|WP_003725720.1\|540466_541402_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	6.72103e-154

>NC_017537.1|WP_003725720.1|540466_541402_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGADRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSNIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>NC_017537.1|WP_003725719.1|539055_540327_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAILSSIINMAIIFKIADWTQKDVENVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>NC_017537.1|WP_003727301.1|538747_539041_+|PTS-sugar-transporter-subunit-IIB
MKKKKIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>NC_017537.1|WP_003730559.1|537685_538732_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEQPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPDELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>NC_017537.1|WP_003725716.1|537038_537689_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLEVLEKNGIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNAELAKECTLAGADLIVVGSYLFEGDIEANLEKLSKGVLTE
>NC_017537.1|WP_003725715.1|536629_537028_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMFVVMIYATTILYAKWTLAYYLPKKMNQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>NC_017537.1|WP_003721289.1|536145_536613_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQDKEKLLTEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>NC_017537.1|WP_012581894.1|535515_536118_+|SIS-domain-containing-protein
MDKQAILDNIHQTWQEEANAISRLPEVTSEEALVKTVETIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGATENPDSVIAKEADIFFPVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>NC_017537.1|WP_012581895.1|533451_535512_+|BglG-family-transcription-antiterminator
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTAKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYTFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADINDSNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>NC_017537.1|WP_012581896.1|532692_533343_+|transaldolase
MHLDSANLEDVKKIQTSSIFKGITTNPTILVKEKCNRQTAIKRILEHTDKQVFVQTVGFSYEEILADARMLLAMFGKEKIAIKIPAHEAGINVIDTLKKEDKTIQILGTAIYSADQAIAAALAGADFVAPYVNRMSAANIDPFKEIAGMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYLQMTNKVLAVEAIRVFNKDATLYEK
>NC_017537.1|WP_012581893.1|542133_542775_-|hypothetical-protein
MKKFVTAMLFLTFLLLVGCSAQNEKAAPPSEKEVKVTKETKISKNGSIDADYDIPEDSKELENKSEDIVKVKLVKNKKIGDYDKEKMEYSSTISEVEVLETYKGTFKKGDKIDVSEPWYLNEGAYESIENYIALEQEQEYTLFLRGGHDSEKLSSIISMGYGKFNEDLKETDATLTDFENLGEVEAYNFISEEQEEVTNYTEIKEDVLKEFND
>NC_017537.1|WP_012581892.1|542785_543322_-|hypothetical-protein
MKQSKKSWKVMAAIVIILSITFTTTLTSNAADLRNGSAFSFKLSDPKGKFNNGATISAHKKAFDTAYAKINASSSRIKLVRSGSGPTIRTRSTNKRDEWYGQMSGNSKGSTITINKYTTTRDKFNQANYNKTALHEMGHAFGMKHQSSSSITVMKQGKYAYNDYTTLDKNNIKYKYGK
>NC_017537.1|WP_012581891.1|543545_544226_+|type-1-glutamine-amidotransferase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKSTSDKLSFFPESLNVFHWHQDTFALPAGATRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILQIDEAFITSGKYVQSVEVMREKDVPEDNKQMLEAILDYLINPKTI
>NC_017537.1|WP_041176481.1|544250_544610_-|Lin0512-family-protein
MEQILFIQTGFGVDVHGQNITKAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADKLDEDAIRAIIPYGTVTIEKIAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>NC_017537.1|WP_003725724.1|544616_545075_-|winged-helix-turn-helix-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTTAGKELENELGAAQRKQMAEIFANSSDTDGLHFTEVMEGYAKNRPGAALIKDFKE
>NC_017537.1|WP_012581889.1|545455_547297_+|LapB-repeat-containing-protein
MKKVLKIFLVTICMFIMIYPSTAAHAEETSDVVNIPDDNLKAYLNGQLKQSGVAPITKKQLATITNVTLSGTSYTDLTGLEEADNLVTLSLNNTNIKTLEPIKNQTSLTYITVSGDNVKDSLFVDLNGLVNLQSLSISGSEVTHNVFKMFNKLPKLTYLYAQNSMKITDISELASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNEANQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSSRLSITDDGITVSGVTKEEFDNLNEIEYNARYDFPTGSYPTPPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDATSEEQFLKDIHAETDDGTAVQSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLHATNDRGQQADPVTVIVTVTASDGGHVNPIPPTPEVKPTPQEETDPTIIPEPQSENSEDQVKENNTKTEEKANKTSLTTKENKVEKADKAEKAEKANQAKTKALPQTGDTNKNGLPIAGVMLSLAALLIIRKSKS
>NC_017537.1|WP_003721301.1|547397_547829_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NC_017537.1|WP_012581888.1|547875_549306_-|CapA-family-protein
MKKLTYIIITGLVLVFIVGAFWITNSTNKTEQKATPTETPKKAKPANVKTISSQAKKTLNSLASSGADKASISDLNQLIKELKSYQVEKNDSGTYLQNLTACLEAVKSYTTGKADEKALGKVYPDFLASEQKLSAIEKTSQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFKKNNGNNTYVFKNCLPWFKSDDYTVINAESAFTNATKAENKMWRIKSDPAHVAFLPASGVDAANLANNHTMDYFQVGYDETLKAFKDNNIPVFNADAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTQEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>NC_017537.1|WP_012581887.1|549426_550242_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDQRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGISPKGFADSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NC_017537.1|WP_012581886.1|550594_551317_+|CRISPR-associated-endoribonuclease-Cas6
MRLKINCDFDSKIIPKDFQSKVVSLFKAGIMKSSPERYENLFGGNKHKQYTFSVYLPKPQNKGAEIQLNEANCIINFSTGDAETGIIFYNALMSLRGSKVLFGAGNHITVKNIQIVPEKKIIGKRTVLRTLSPVVSRDHNRETFKNWFYSFEDEEFEPTLKRNMLPYLIDAFGEQARYDLEKLKITPISMKKVVVYCHEIHIESSVGIFELEAEAYLQKYLVENGLGTMTGSGFGMIEQL

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Crispr_ID: NC_017537_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017537_3

557670-559450

Unclear

I-A

Consensus_repeat	Method
GTTTTAACTACTTATTATGAAATGTAAAT	PILER-CR
GTTTTAACTACTTATTATGAAATGTAAAT	CRISPRCasFinder
GTTTTAACTACTTATTATGAAATGTAAAT	CRT

27 spacers

cas2,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NC_017537_3

>merge|NC_017537|3|557670-559450|PILER-CR,CRISPRCasFinder,CRT
GTTTTAACTACTTATTATGAAATGTAAATTTTTTTTGGCTTTTTCTTTAGACACTTTTAACTTGTTTTAACTACTTATTATGAAATGTAAATTTGTTTGGAAAACGTGCGCGCCAGCCTTCTTTTTTGTTTTAACTACTTATTATGAAATGTAAATTGTATTCTTATAATGAGCTTTGCAAAATGGTTCCCCGTTTTAACTACTTATTATGAAATGTAAATTCACCAATTCATGTCCTACTAGCTTCGGACGTTTCATGTTTTAACTACTTATTATGAAATGTAAATACGGTTGAATAAAACGAATAATAAACTGCATGTATGTTTTAACTACTTATTATGAAATGTAAATAAGCTAGTCGCGAACAATTAAGCGCGTTAGCCCCGTTTTAACTACTTATTATGAAATGTAAATCAACGCTTTTTATTGATATGATACTATATGACATTAGTTTTAACTACTTATTATGAAATGTAAATTGCTTCTTGCTGTTCTTTCTCTTTTTTAAGATTTCATGTTTTAACTACTTATTATGAAATGTAAATGTCTTTTAGCCTGCTTTTGGTTAAAGTGGGGTTGTCGTTTTAACTACTTATTATGAAATGTAAATTACTTAGCACCTACAAGACTAGCATCACCCTGCGCAGTTTTAACTACTTATTATGAAATGTAAATATCTACAGAACTCTCCGACTCTTGCACTTCCGTGATAGTTTTAACTACTTATTATGAAATGTAAATATTGGACCGGAAACTGCAGGCGACTTACTTAATTATCGTTTTAACTACTTATTATGAAATGTAAATACAGTCAAATGATGATGACCAACTTCCTCTGCCAAAGGTTTTAACTACTTATTATGAAATGTAAATTACATTAGTGTATCGAAATCCGTATCGAAAATTTCTACGTTTTAACTACTTATTATGAAATGTAAATAAAATTGATCATCAGGTAAACTAGCAACATCAAGTTGTTTTAACTACTTATTATGAAATGTAAATGGAAACGCCGTCTTCCGTCGTTCTAAATTTAAAACTGTTTTAACTACTTATTATGAAATGTAAATTATAAATTAAGGATAAGGAGTGTTTTTGGATGGCGTTTTAACTACTTATTATGAAATGTAAATCTTTCTGGAGCAACTTTTAAAGTGAAAGACAGTGAGTTTTAACTACTTATTATGAAATGTAAATTATCTTTATCTGTAGCTAGTTTGAAATCATCTTCATGTTTTAACTACTTATTATGAAATGTAAATGAAAGTAAAGAAATCAAGCCTAAATTTGTTTTCCGGTGTTTTAACTACTTATTATGAAATGTAAATGGTTTTAACTTCTAGGTTATTTTGTGCATTTTTTGGGTTTTAACTACTTATTATGAAATGTAAATTATTCTTTTAAAGTTGGCGGTAGTATGGTAACTAGTTTTAACTACTTATTATGAAATGTAAATATGTCTGCGTGCCCCAGTCTCTCTTGGATTACTTTGGTTTTAACTACTTATTATGAAATGTAAATTTTTCAATGTGCGAGTATGCTCCTCTGGAAATTCCTGTTTTAACTACTTATTATGAAATGTAAATATCTTGAACCGCTCCCCATGCTTTTTTAGCGCCATCAGTTTTAACTACTTATTATGAAATGTAAATTAACAATGAAAAACGGATTTACAAAATTAGCGTCCGTTTTAACTACTTATTATGAAATGTAAATACTAACAAAGCACCTGTAAAAGCTAATGCAATCGGAGTTTTAACTACTTATTATGAAATCATAAA

>NC_017537|3|2|557670-559385|PILER-CR
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTTTTGGCTTTTTCTTTAGACACTTTTAACTT
GTTTTAACTACTTATTATGAAATGTAAAT	TTGTTTGGAAAACGTGCGCGCCAGCCTTCTTTTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TGTATTCTTATAATGAGCTTTGCAAAATGGTTCCCC
GTTTTAACTACTTATTATGAAATGTAAAT	TCACCAATTCATGTCCTACTAGCTTCGGACGTTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	ACGGTTGAATAAAACGAATAATAAACTGCATGTAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAGCTAGTCGCGAACAATTAAGCGCGTTAGCCCC
GTTTTAACTACTTATTATGAAATGTAAAT	CAACGCTTTTTATTGATATGATACTATATGACATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGCTTCTTGCTGTTCTTTCTCTTTTTTAAGATTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	GTCTTTTAGCCTGCTTTTGGTTAAAGTGGGGTTGTC
GTTTTAACTACTTATTATGAAATGTAAAT	TACTTAGCACCTACAAGACTAGCATCACCCTGCGCA
GTTTTAACTACTTATTATGAAATGTAAAT	ATCTACAGAACTCTCCGACTCTTGCACTTCCGTGATA
GTTTTAACTACTTATTATGAAATGTAAAT	ATTGGACCGGAAACTGCAGGCGACTTACTTAATTATC
GTTTTAACTACTTATTATGAAATGTAAAT	ACAGTCAAATGATGATGACCAACTTCCTCTGCCAAAG
GTTTTAACTACTTATTATGAAATGTAAAT	TACATTAGTGTATCGAAATCCGTATCGAAAATTTCTAC
GTTTTAACTACTTATTATGAAATGTAAAT	AAAATTGATCATCAGGTAAACTAGCAACATCAAGTT
GTTTTAACTACTTATTATGAAATGTAAAT	GGAAACGCCGTCTTCCGTCGTTCTAAATTTAAAACT
GTTTTAACTACTTATTATGAAATGTAAAT	TATAAATTAAGGATAAGGAGTGTTTTTGGATGGC
GTTTTAACTACTTATTATGAAATGTAAAT	CTTTCTGGAGCAACTTTTAAAGTGAAAGACAGTGA
GTTTTAACTACTTATTATGAAATGTAAAT	TATCTTTATCTGTAGCTAGTTTGAAATCATCTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	GAAAGTAAAGAAATCAAGCCTAAATTTGTTTTCCGGT
GTTTTAACTACTTATTATGAAATGTAAAT	GGTTTTAACTTCTAGGTTATTTTGTGCATTTTTTGG
GTTTTAACTACTTATTATGAAATGTAAAT	TATTCTTTTAAAGTTGGCGGTAGTATGGTAACTA
GTTTTAACTACTTATTATGAAATGTAAAT	ATGTCTGCGTGCCCCAGTCTCTCTTGGATTACTTTG
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTCAATGTGCGAGTATGCTCCTCTGGAAATTCCT
GTTTTAACTACTTATTATGAAATGTAAAT	ATCTTGAACCGCTCCCCATGCTTTTTTAGCGCCATCA
GTTTTAACTACTTATTATGAAATGTAAAT	TAACAATGAAAAACGGATTTACAAAATTAGCGTCC
GTTTTAACTACTTATTATGAAATGTAAAT

>NC_017537|3|2|557670-559450|CRISPRCasFinder
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTTTTGGCTTTTTCTTTAGACACTTTTAACTT
GTTTTAACTACTTATTATGAAATGTAAAT	TTGTTTGGAAAACGTGCGCGCCAGCCTTCTTTTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TGTATTCTTATAATGAGCTTTGCAAAATGGTTCCCC
GTTTTAACTACTTATTATGAAATGTAAAT	TCACCAATTCATGTCCTACTAGCTTCGGACGTTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	ACGGTTGAATAAAACGAATAATAAACTGCATGTAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAGCTAGTCGCGAACAATTAAGCGCGTTAGCCCC
GTTTTAACTACTTATTATGAAATGTAAAT	CAACGCTTTTTATTGATATGATACTATATGACATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGCTTCTTGCTGTTCTTTCTCTTTTTTAAGATTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	GTCTTTTAGCCTGCTTTTGGTTAAAGTGGGGTTGTC
GTTTTAACTACTTATTATGAAATGTAAAT	TACTTAGCACCTACAAGACTAGCATCACCCTGCGCA
GTTTTAACTACTTATTATGAAATGTAAAT	ATCTACAGAACTCTCCGACTCTTGCACTTCCGTGATA
GTTTTAACTACTTATTATGAAATGTAAAT	ATTGGACCGGAAACTGCAGGCGACTTACTTAATTATC
GTTTTAACTACTTATTATGAAATGTAAAT	ACAGTCAAATGATGATGACCAACTTCCTCTGCCAAAG
GTTTTAACTACTTATTATGAAATGTAAAT	TACATTAGTGTATCGAAATCCGTATCGAAAATTTCTAC
GTTTTAACTACTTATTATGAAATGTAAAT	AAAATTGATCATCAGGTAAACTAGCAACATCAAGTT
GTTTTAACTACTTATTATGAAATGTAAAT	GGAAACGCCGTCTTCCGTCGTTCTAAATTTAAAACT
GTTTTAACTACTTATTATGAAATGTAAAT	TATAAATTAAGGATAAGGAGTGTTTTTGGATGGC
GTTTTAACTACTTATTATGAAATGTAAAT	CTTTCTGGAGCAACTTTTAAAGTGAAAGACAGTGA
GTTTTAACTACTTATTATGAAATGTAAAT	TATCTTTATCTGTAGCTAGTTTGAAATCATCTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	GAAAGTAAAGAAATCAAGCCTAAATTTGTTTTCCGGT
GTTTTAACTACTTATTATGAAATGTAAAT	GGTTTTAACTTCTAGGTTATTTTGTGCATTTTTTGG
GTTTTAACTACTTATTATGAAATGTAAAT	TATTCTTTTAAAGTTGGCGGTAGTATGGTAACTA
GTTTTAACTACTTATTATGAAATGTAAAT	ATGTCTGCGTGCCCCAGTCTCTCTTGGATTACTTTG
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTCAATGTGCGAGTATGCTCCTCTGGAAATTCCT
GTTTTAACTACTTATTATGAAATGTAAAT	ATCTTGAACCGCTCCCCATGCTTTTTTAGCGCCATCA
GTTTTAACTACTTATTATGAAATGTAAAT	TAACAATGAAAAACGGATTTACAAAATTAGCGTCC
GTTTTAACTACTTATTATGAAATGTAAAT	ACTAACAAAGCACCTGTAAAAGCTAATGCAATCGGA
GTTTTAACTACTTATTATGAAATCATAAA

>NC_017537|3|3|557670-559450|CRT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTTTTGGCTTTTTCTTTAGACACTTTTAACTT
GTTTTAACTACTTATTATGAAATGTAAAT	TTGTTTGGAAAACGTGCGCGCCAGCCTTCTTTTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TGTATTCTTATAATGAGCTTTGCAAAATGGTTCCCC
GTTTTAACTACTTATTATGAAATGTAAAT	TCACCAATTCATGTCCTACTAGCTTCGGACGTTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	ACGGTTGAATAAAACGAATAATAAACTGCATGTAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAGCTAGTCGCGAACAATTAAGCGCGTTAGCCCC
GTTTTAACTACTTATTATGAAATGTAAAT	CAACGCTTTTTATTGATATGATACTATATGACATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGCTTCTTGCTGTTCTTTCTCTTTTTTAAGATTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	GTCTTTTAGCCTGCTTTTGGTTAAAGTGGGGTTGTC
GTTTTAACTACTTATTATGAAATGTAAAT	TACTTAGCACCTACAAGACTAGCATCACCCTGCGCA
GTTTTAACTACTTATTATGAAATGTAAAT	ATCTACAGAACTCTCCGACTCTTGCACTTCCGTGATA
GTTTTAACTACTTATTATGAAATGTAAAT	ATTGGACCGGAAACTGCAGGCGACTTACTTAATTATC
GTTTTAACTACTTATTATGAAATGTAAAT	ACAGTCAAATGATGATGACCAACTTCCTCTGCCAAAG
GTTTTAACTACTTATTATGAAATGTAAAT	TACATTAGTGTATCGAAATCCGTATCGAAAATTTCTAC
GTTTTAACTACTTATTATGAAATGTAAAT	AAAATTGATCATCAGGTAAACTAGCAACATCAAGTT
GTTTTAACTACTTATTATGAAATGTAAAT	GGAAACGCCGTCTTCCGTCGTTCTAAATTTAAAACT
GTTTTAACTACTTATTATGAAATGTAAAT	TATAAATTAAGGATAAGGAGTGTTTTTGGATGGC
GTTTTAACTACTTATTATGAAATGTAAAT	CTTTCTGGAGCAACTTTTAAAGTGAAAGACAGTGA
GTTTTAACTACTTATTATGAAATGTAAAT	TATCTTTATCTGTAGCTAGTTTGAAATCATCTTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	GAAAGTAAAGAAATCAAGCCTAAATTTGTTTTCCGGT
GTTTTAACTACTTATTATGAAATGTAAAT	GGTTTTAACTTCTAGGTTATTTTGTGCATTTTTTGG
GTTTTAACTACTTATTATGAAATGTAAAT	TATTCTTTTAAAGTTGGCGGTAGTATGGTAACTA
GTTTTAACTACTTATTATGAAATGTAAAT	ATGTCTGCGTGCCCCAGTCTCTCTTGGATTACTTTG
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTCAATGTGCGAGTATGCTCCTCTGGAAATTCCT
GTTTTAACTACTTATTATGAAATGTAAAT	ATCTTGAACCGCTCCCCATGCTTTTTTAGCGCCATCA
GTTTTAACTACTTATTATGAAATGTAAAT	TAACAATGAAAAACGGATTTACAAAATTAGCGTCC
GTTTTAACTACTTATTATGAAATGTAAAT	ACTAACAAAGCACCTGTAAAAGCTAATGCAATCGGA
GTTTTAACTACTTATTATGAAATCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017537.1\|WP_003740448.1\|561584_562589_+\|ROK-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224851
NC_017537.1\|WP_012581878.1\|567287_568028_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NC_017537.1\|WP_003730183.1\|562620_563937_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|133432
NC_017537.1\|WP_012581888.1\|547875_549306_-\|CapA-family-protein	unknown	unknown	gnl\|CDD\|225399
NC_017537.1\|WP_003721310.1\|557193_557472_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_017537.1\|WP_012581880.1\|559522_559891_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
NC_017537.1\|WP_003730181.1\|560037_561453_+\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_017537.1\|WP_003730185.1\|564998_565442_+\|hypothetical-protein	unknown	unknown	unknown
NC_017537.1\|WP_012581877.1\|568267_569743_+\|hypothetical-protein	unknown	unknown	unknown
NC_017537.1\|WP_012581886.1\|550594_551317_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_017537.1\|WP_012581883.1\|553866_554490_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
NC_017537.1\|WP_012581876.1\|569735_571232_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227617
NC_017537.1\|WP_003721316.1\|564138_564891_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NC_017537.1\|WP_012581889.1\|545455_547297_+\|LapB-repeat-containing-protein	unknown	unknown	gnl\|CDD\|380190
NC_017537.1\|WP_012581885.1\|551332_553021_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09754_cas8b2_CAS-I-B	gnl\|CDD\|187884
NC_017537.1\|WP_012581884.1\|553010_553880_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NC_017537.1\|WP_012581887.1\|549426_550242_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NC_017537.1\|WP_012581882.1\|554707_556891_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_017537.1\|WP_003721301.1\|547397_547829_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NC_017537.1\|WP_012581879.1\|565487_567149_-\|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl\|CDD\|223732

Protein	Function_ID	Function_description	E-value
NC_017537.1\|WP_003740448.1\|561584_562589_+\|ROK-family-transcriptional-regulator	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	5.58402e-21
NC_017537.1\|WP_012581878.1\|567287_568028_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	5.20301e-52
NC_017537.1\|WP_003730183.1\|562620_563937_-\|6-phospho-beta-glucosidase	gnl\|CDD\|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NC_017537.1\|WP_012581888.1\|547875_549306_-\|CapA-family-protein	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	1.55499e-102
NC_017537.1\|WP_003721310.1\|557193_557472_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.1393e-30
NC_017537.1\|WP_012581880.1\|559522_559891_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	2.99459e-41
NC_017537.1\|WP_003730181.1\|560037_561453_+\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.51452e-80
NC_017537.1\|WP_012581886.1\|550594_551317_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.40258e-33
NC_017537.1\|WP_012581883.1\|553866_554490_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	8.56288e-25
NC_017537.1\|WP_012581876.1\|569735_571232_+\|hypothetical-protein	gnl\|CDD\|227617	COG5298, COG5298, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_017537.1\|WP_003721316.1\|564138_564891_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.24308e-64
NC_017537.1\|WP_012581889.1\|545455_547297_+\|LapB-repeat-containing-protein	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	1.15539e-120
NC_017537.1\|WP_012581885.1\|551332_553021_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	4.00353e-23
NC_017537.1\|WP_012581884.1\|553010_553880_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	2.98892e-55
NC_017537.1\|WP_012581887.1\|549426_550242_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.85144e-49
NC_017537.1\|WP_012581882.1\|554707_556891_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	4.57689e-59
NC_017537.1\|WP_003721301.1\|547397_547829_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
NC_017537.1\|WP_012581879.1\|565487_567149_-\|SulP-family-inorganic-anion-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	6.94056e-147

>NC_017537.1|WP_003721310.1|557193_557472_+|CRISPR-associated-endonuclease-Cas2
MYVILIYDISIENGGAKVWRNVFKICKKYLTHVQKSVFEGEITPALLVKLRMELDKYIRDDQDSVIVFSSRQQRWLEKEFWGLTDEKTSNFF
>NC_017537.1|WP_012581882.1|554707_556891_+|CRISPR-associated-helicase/endonuclease-Cas3
MHKYLAKSNPEETIQEHTDNLLKNYQRLKKLYPAVEIDWYLLELVCLLHDLGKMNLLFQTKLGNASGKGKEIPHGYLSVAFVPDSKLEEMGYSEDEIKVVYQAVARHHERKYDFSDSEWKNEIIRLEEQWEGFNYSQLGENAEYSSEVEMLYFYPGSRIFEGNSVADTETFKKYVLLKGLLNRIDFAASGGIDVELENDFLIDSMDVQLAHFKAENPEADWNALQKYMMQHQNENIVVIAETGMGKTEAGLLWLGNNKGFFTLPLRAAINAIYERITKNIVTTNQAERVGLLHSETYSQYLLHEGNAEMDIDEYYTRTRQMSLPITICTLDQLFDFVFRYAGFEHKLATLSYSKVIIDEIQMYSPDLLAYLILGLSYIDKFGGKFCIMTATLPGIVTDLLLENGVDFVQPEEKFVSSRIRHSMEMVHTEIESEFIKPFFNNNRILVICNTISKAKKIYSELKDHFQGEEIHLIHSQFIKRDRSAKEKAIFKDGQKDSTKKCIWVATQVVEASLDIDFDLLFTELSDVNGLFQRMGRCYRNRALDVDTNVYVFDGGAKVCSGVGIFIDKLIFENSKAILNEHAGVLTEEKKMELVEQVYSAEALRGSEFYNDLIGTINYVKAFDSYELDKAEVRMRFRNINSVSVIPEEVWQDNVEEINSYFVTLRKTSKEISTKEKMIARTNLAEFMVSVPDYLYKKGESVVREINRYESVIEFKCGYSSDVGVFMR
>NC_017537.1|WP_012581883.1|553866_554490_+|type-I-B-CRISPR-associated-protein-Cas5
MKAIRVKLWQDLVNFKKPTSFQLKETYPLPPYSTVIGMVHTLCGFTSYHEMKISIQGKYFSKVNDLATRYEFKNGMTYDASRHQIKVDKYGVSRGVSTVELIVDLELLLHIIPEDSSLVPIIEKAFSEPIEFPSLGRREDIATIQKVDIVDVEKRQPSKSTEISDGYNAYVPISLTENNSIHFKSHESSVGRDKLLGTRYLLTEKYE
>NC_017537.1|WP_012581884.1|553010_553880_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKNKGLAMTIIFQAESANYGESLGNISSLKKISRNNGDQYTYISRQAIRYNLMDQIGEKEAPVKAEGGGDKKVIQFLSEATITDFPELDFFGYLKTEKGSGGQKRSAKVRLSNAISLETFKGDLDFLTNKGQADKLNENMNIAQAEIHKSYYRYTITIDLDQIGIDGEIALDNKEKARRVKKLMDTVAFLYRDIRGRREDLKPLFVIGGVYDVKNPVFQNIVDVADNNIVIKNIKDLLTYEDIKENTRVGIIDGQFANSDEVKAELKAESVPAFFNDIKGKIDAYYESN
>NC_017537.1|WP_012581885.1|551332_553021_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MQTEIELRADDWLINAGLVGFLNIVGKENVRINGQSIYFKADLLVGFEDKYFNFFIQEYKETLAWFKIVSYKDTMERFRAEDFASFDEKALNDLNKYMKDVVKFYLKKSNYIKVFSLIDAKANVTKWLENLNAINLTKKQQWEDVKVDIVEKVKRNYIQLDFIIDFCLGEKGLKYLGAKNLIYSVINKGWTGTSFLYTKTKFADPYLDYKTSFLDPVLDYVDSDLSKAKYNCFNCNLPIKNLKTGLSFMNDIGFDIEKKTSHVWDFNNDVATCPICRLIYSCVPAGFTYVYGEGMFVNDSYGVEELHRVNERMRNSILRFNQDGINSTNTYRALVESITMEHENNRRYELADIQLVRYENEHYRFNLLSKKMLHIVNDSKGILKSLIRCGYKEGNLNVNLYKEVIQHLMNNENLFTLIHKLIYYKQTSVNGLYYNMGHVSGILDINTKFLKEMEVMTNISQNQLWFVQNCGKEFKEGYVKKKSENKISGITYKLLNSLKVNDKDGFMDTLLNSYSYLSMPIPDVFIKMFSNNEAFKSVGYAFMLGVGGEKTKKENGGNTDEK
>NC_017537.1|WP_012581886.1|550594_551317_+|CRISPR-associated-endoribonuclease-Cas6
MRLKINCDFDSKIIPKDFQSKVVSLFKAGIMKSSPERYENLFGGNKHKQYTFSVYLPKPQNKGAEIQLNEANCIINFSTGDAETGIIFYNALMSLRGSKVLFGAGNHITVKNIQIVPEKKIIGKRTVLRTLSPVVSRDHNRETFKNWFYSFEDEEFEPTLKRNMLPYLIDAFGEQARYDLEKLKITPISMKKVVVYCHEIHIESSVGIFELEAEAYLQKYLVENGLGTMTGSGFGMIEQL
>NC_017537.1|WP_012581887.1|549426_550242_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDQRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGISPKGFADSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>NC_017537.1|WP_012581888.1|547875_549306_-|CapA-family-protein
MKKLTYIIITGLVLVFIVGAFWITNSTNKTEQKATPTETPKKAKPANVKTISSQAKKTLNSLASSGADKASISDLNQLIKELKSYQVEKNDSGTYLQNLTACLEAVKSYTTGKADEKALGKVYPDFLASEQKLSAIEKTSQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFKKNNGNNTYVFKNCLPWFKSDDYTVINAESAFTNATKAENKMWRIKSDPAHVAFLPASGVDAANLANNHTMDYFQVGYDETLKAFKDNNIPVFNADAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTQEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>NC_017537.1|WP_003721301.1|547397_547829_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>NC_017537.1|WP_012581889.1|545455_547297_+|LapB-repeat-containing-protein
MKKVLKIFLVTICMFIMIYPSTAAHAEETSDVVNIPDDNLKAYLNGQLKQSGVAPITKKQLATITNVTLSGTSYTDLTGLEEADNLVTLSLNNTNIKTLEPIKNQTSLTYITVSGDNVKDSLFVDLNGLVNLQSLSISGSEVTHNVFKMFNKLPKLTYLYAQNSMKITDISELASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNEANQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSSRLSITDDGITVSGVTKEEFDNLNEIEYNARYDFPTGSYPTPPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDATSEEQFLKDIHAETDDGTAVQSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLHATNDRGQQADPVTVIVTVTASDGGHVNPIPPTPEVKPTPQEETDPTIIPEPQSENSEDQVKENNTKTEEKANKTSLTTKENKVEKADKAEKAEKANQAKTKALPQTGDTNKNGLPIAGVMLSLAALLIIRKSKS
>NC_017537.1|WP_012581880.1|559522_559891_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAEFAETVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVAVLLV
>NC_017537.1|WP_003730181.1|560037_561453_+|multidrug-efflux-MFS-transporter
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGENGWGSATVLVSIIVGGLALGLFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGVGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK
>NC_017537.1|WP_003740448.1|561584_562589_+|ROK-family-transcriptional-regulator
MAIPRDLKELNKKNIKSILRQQGAMTKAEIAEVTGLSVVTVNKLIRDLVENEEILEQDNSVATGGRRAVSYEINPNFQQVLVISLQEKWKKITYSFSVYNLLGEPEFVEDMSGEDLDITALKRNTKDLVCAFPKISCVVIGVPGIEIGGKLRAMDFPLLLNVQLRETLEAEVNLPVLVETDTNAAILGYKNRPVKEENIVGLYYPERFPPGAGLLMNGEILKGQNGLAGEIKHMPLQVDWDNFDFSVDEIKAHIRKMVLLTMSFYDPETIVLYTNFYFGQKDFTEELTEELKQVYPYAVLPEIVLSRKFTTDYRIGLLAFGIDYLENNMTDWRI
>NC_017537.1|WP_003730183.1|562620_563937_-|6-phospho-beta-glucosidase
MTKGIKIATIGGGSSYTPELIEGFIKRQDELPVRELWLVDVEAGREKLEIVGNLAKRMVEKAGVDMEVHLTLDREEALKGADFVTTQLRVGLLDARVKDERIPNSYGVVGQETNGPGGMFKGLRTIPVILDICKDMERLCPDAWLINFANPAGMVTEAVLRYSNQKKVVGLCNGPIGIERNIAETLGVDVSEIYVEFVGLNHMVFAKTVYHNGKDVTKDVVFKMTEDEAGSSLKNINATGWDKTFLRTLNMIPIDYLRYYWQTKQQLEDQARAYAEHGTRAEVVKKVEAELFELYKQEELAEKPKQLEQRGGAYYSEAACNLINSIYNDKRDIQIVNTRNNGAILDIDPDSAVETNCVITRQGPIPLASGRLPIAINGIIQEIKTFERLTAEAAVTGDYDKALLAMTINPLTPSESVAREMLDELLEAHKEYLPNFFK
>NC_017537.1|WP_003721316.1|564138_564891_+|MurR/RpiR-family-transcriptional-regulator
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFSEFRVKLQLYLEEQKLAQIDMADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGVGSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLSDKICMIAISVEGENEDIIRYIHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIAREIRTQLDKEKM
>NC_017537.1|WP_003730185.1|564998_565442_+|hypothetical-protein
MYSNMKEKVVFTLIMCSLMILCMSSYNIFLENGIGTDSLLIVLKAFVPFLFIGFLLDFFVVGKIVYRLHALLVSEDASKFKKIIMMQLLMVTFMCVLMSTLSLIVNQGEWSHLGFLILRNYFVALFLQIFIVSPFVRLISPRIFALL
>NC_017537.1|WP_012581879.1|565487_567149_-|SulP-family-inorganic-anion-transporter
MFKHILLSLNGYKISYLRNDVISGVGVAALTIPVAMGYAQVAGLPPIYGLYASFLPVIAYVIFASSPQLIFGIDATASAITGSIILGTAGLAAGSKEAIALAPILAFFCAIFLVLFSVLKLGRFAKYISAPVLSGFISGLSVSIIMGQIPKIMGLKESGDSFFSSLGIIFGQFFQSNWISFAMGVVTVIIVITCKKVIPKIPMSLVVLILGTMAAYFFRLDQYNVDIVGKIPVGFPSLALPDFGASSWALAIGGGLVCAIATFAGSLLPSESFAMRNKYTIDDNRELFAYGISNFVAAFSGCSPASASVSRTAANEQFRGKTQMVSIVAATIIALIVAFLSGLLYYMPQPVLSGIVFAALVGIIDVDVLKGLFKVSRREATVWIVAALGTLLVGVIFGVLLGIFLSFINVVSRSMKSPIAILGVIEGRHGYFDLKRKPEAKPIPNVVIYRYSASLFFGNFNKFADGLKEAVQDDTKLVIFEASAIINIDTTATESMKDLLKWLDDKGIEYYFADLIDHLKTSFRKHDLGYIIDNGYTKKTVEDALDAYHAEHK
>NC_017537.1|WP_012581878.1|567287_568028_-|MerR-family-transcriptional-regulator
MQIKDLAELTGVSVRTLHHYDKIGLLVPQKDDWNGYRIYSENDVDKLQQILFFKELDFPLKKIKQILDDPFFDKNVALDLQRHLLIEKKQRIETMLATLDQTIRNEKGEITMTNKEKFTGFDFSTNPYEEEAKKRWGDKVVEKANEKVNNMSEKEKLTLKESFDAEFRHLASVRELAPESEEAQLAIDHFFHYLNDTHGNIYSLEAFAGLGEMYVADERFTKNIDQFGDGLSHFLKEAMNIYAKTK
>NC_017537.1|WP_012581877.1|568267_569743_+|hypothetical-protein
MKGKIKSSSMWLWHHLTPQIFAVICVFIITLIALFVPPYIGMADNGDFFRIFSSNGLFVNNTNYDALQFGHFVKEFGIYQYFNENQVAIYSSQSIFIQMALLLNKLFWSTTVFDVRFLGGLQLALLLPAIYLLVAGLTAKMKGWPGYVVAALTVFIFADTAYTAYFNSFFSEGLILIMMLYISAGFLLLYQHKYNDYAMLGLIFVASLILITAKQQNAPIAVVIAVCGILVFFIRKNRAFRISAAATFFVIFLSGVVMYAFIPGEFVTINQYQTMTRGVLLDSENPEKSLEEMGMNSEFALLKGTNFYQKYKMIDLDSKLMEKEFYPNYNFVTVLSYYLENPKQFGKMLDLSAQNSFSIRPFEMGNFEKATGYKFKEKTHFFSIYSDVKEKLAPAKFTFLILWALVFLICYGVSAFKHFREKNIRGMLLFDLVVLLIGSGFAVILVTIVGDGEADLTKHNFLFNVCFDLTMLIGAASLLEVYLKKRGERNA
>NC_017537.1|WP_012581876.1|569735_571232_+|hypothetical-protein
MRKKMIVSILLAFVIFVVGEHSVIAKSDDGVVVFYDSLATGTENEGNMDALLRMLNSLGKRVTIYSWEENPDLSQTSEIIVLQNKKDGLSNEWTNKLAKSKAKIAYIGGNPPTFITDKLELKTKVMTDASITIQTAAGLSGKPQLVNETNLITSYKGTSFGEMDAAENGQAAYGIQAGNYAYAPIFQADNTSEFALMDVLKALFDIKTTTNQYAFITGVNPFIDFDLLKKTADTFYEKGIPFIVSAGPVFYNQDFQAAKNYAEILRYVQAKNGTIMMNVPAVTYGDSPAGELERIMQKSVHFFAENDVAPLGVTAELYWNFDKVYGVEGFAPFNTGILLPNQKIIHTTKVNNGSAFEKSPYSVANDLYATTTEGRNFPIDIAITYSFFDNEKELKAAAEELANDNISDFRFQDHEVKTNKDTIESSAGSLYINNQSVTLDDDLNYIKTKNKTVKQAGSLEGFFGYQNTFFTIVIVLSLGIIGVLFVFGYRLYMKKYMK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017537_3	3.11\|558345\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558345-558381	37	NC_017537.1	80782-80818	0	1.0
NC_017537_3	3.19\|558867\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558867-558902	36	NC_017537.1	1265069-1265104	2	0.944
NC_017537_3	3.24\|559191\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559191-559226	36	NC_017537.1	2703464-2703499	2	0.944

1. spacer 3.11|558345|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to position: 80782-80818, mismatch: 0, identity: 1.0

atctacagaactctccgactcttgcacttccgtgata	CRISPR spacer
atctacagaactctccgactcttgcacttccgtgata	Protospacer
*************************************

2. spacer 3.19|558867|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to position: 1265069-1265104, mismatch: 2, identity: 0.944

tatctttatctgtagctagtttgaaatcatcttcat	CRISPR spacer
tatcttcatctgtagctagtttaaaatcatcttcat	Protospacer
******.***************.*************

3. spacer 3.24|559191|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to position: 2703464-2703499, mismatch: 2, identity: 0.944

ttttcaatgtgcgagtatgctcctctggaaattcct	CRISPR spacer
ttttcaatatgcgagtaagctcctctggaaattcct	Protospacer
********.******** ******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017537_3	3.7\|558084\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558084-558119	36	NC_009813	Listeria phage B054, complete genome	25999-26034	0	1.0
NC_017537_3	3.13\|558477\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558477-558513	37	AJ312240	Bacteriophage PSA complete genome	21457-21493	0	1.0
NC_017537_3	3.7\|558084\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558084-558119	36	MH341453	Listeria phage PSU-VKH-LP041, complete genome	26472-26507	1	0.972
NC_017537_3	3.21\|558998\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558998-559033	36	DQ003637	Listeria phage A500, complete genome	25196-25231	1	0.972
NC_017537_3	3.8\|558149\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558149-558185	37	KJ094023	Listeria phage LP-101, complete genome	20315-20351	2	0.946
NC_017537_3	3.13\|558477\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558477-558513	37	NC_009812	Listeria phage B025, complete genome	26375-26411	2	0.946
NC_017537_3	3.13\|558477\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558477-558513	37	KJ094023	Listeria phage LP-101, complete genome	25873-25909	2	0.946
NC_017537_3	3.19\|558867\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558867-558902	36	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	231210-231245	2	0.944
NC_017537_3	3.19\|558867\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558867-558902	36	NC_003216	Listeria phage A118, complete genome	22480-22515	2	0.944
NC_017537_3	3.19\|558867\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558867-558902	36	AJ242593	Bacteriophage A118 complete genome	22480-22515	2	0.944
NC_017537_3	3.20\|558932\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558932-558968	37	KJ094022	Listeria phage LP-030-3, complete genome	24012-24048	2	0.946
NC_017537_3	3.21\|558998\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558998-559033	36	KJ094022	Listeria phage LP-030-3, complete genome	32172-32207	2	0.944
NC_017537_3	3.21\|558998\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558998-559033	36	MH341452	Listeria phage PSU-VKH-LP040, complete genome	23234-23269	2	0.944
NC_017537_3	3.21\|558998\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558998-559033	36	KP399678	Listeria phage vB_LmoS_293, complete genome	23735-23770	2	0.944
NC_017537_3	3.24\|559191\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559191-559226	36	MH341452	Listeria phage PSU-VKH-LP040, complete genome	25212-25247	2	0.944
NC_017537_3	3.24\|559191\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559191-559226	36	DQ003637	Listeria phage A500, complete genome	26746-26781	2	0.944
NC_017537_3	3.13\|558477\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558477-558513	37	MT500540	Listeria phage LP-HM00113468, complete genome	20325-20361	3	0.919
NC_017537_3	3.8\|558149\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558149-558185	37	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	230207-230243	4	0.892
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	JB137888	Sequence 7 from Patent WO2012159774	48410-48445	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	KJ094025	Listeria phage LP-032 contig 2, partial genome	37781-37816	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	MH299806	Listeria phage LP-KV022, complete genome	5235-5270	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	MN114083	Listeria phage LP-013, complete genome	65380-65415	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	NC_021785	Listeria phage LP-110, complete genome	28081-28116	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	MN128593	Listeria phage LP-031, complete genome	65188-65223	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	NC_021787	Listeria phage LP-037, complete genome	22112-22147	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	MN904502	Listeria phage LP-018, complete genome	65004-65039	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	KJ094020	Listeria phage LP-026, complete genome	49282-49317	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	KJ094021	Listeria phage LP-114, complete genome	55231-55266	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	MN114082	Listeria phage LP-010, complete genome	64349-64384	4	0.889
NC_017537_3	3.27\|559386\|36\|NC_017537\|CRISPRCasFinder,CRT	559386-559421	36	JX442241	Listeria phage P70, complete genome	5235-5270	4	0.889
NC_017537_3	3.8\|558149\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558149-558185	37	MK075006	Staphylococcus phage phiSP119-3, complete genome	26312-26348	7	0.811
NC_017537_3	3.8\|558149\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558149-558185	37	AP019562	Staphylococcus phage SP276 DNA, complete genome	35339-35375	7	0.811
NC_017537_3	3.8\|558149\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558149-558185	37	MK075003	Staphylococcus phage phiSP44-1, complete genome	22926-22962	7	0.811
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	LC557520	Staphylococcus phage vB_SsapH-Golestan101-M DNA, complete genome	116646-116679	8	0.765
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	NC_030946	Streptococcus phage phiARI0923, complete genome	18825-18858	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	KY065482	Streptococcus phage IPP42, complete genome	14204-14237	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	KY065483	Streptococcus phage IPP43, complete genome	14644-14677	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	KY065489	Streptococcus phage IPP51, complete genome	14642-14675	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	KY065484	Streptococcus phage IPP44, complete genome	14361-14394	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	KY065481	Streptococcus phage IPP41, complete genome	14025-14058	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	NC_027396	Streptococcus phage SpSL1, complete genome	2030-2063	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	KY065449	Streptococcus phage IPP5, complete genome	15402-15435	9	0.735
NC_017537_3	3.1\|557699\|34\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	557699-557732	34	MN694145	Marine virus AFVG_250M840, complete genome	29048-29081	9	0.735
NC_017537_3	3.26\|559322\|35\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559322-559356	35	HC318808	Sequence 63 from Patent WO2010000854	1719-1753	9	0.743
NC_017537_3	3.26\|559322\|35\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559322-559356	35	HC318804	Sequence 59 from Patent WO2010000854	1722-1756	9	0.743
NC_017537_3	3.26\|559322\|35\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559322-559356	35	HC318806	Sequence 61 from Patent WO2010000854	1722-1756	9	0.743
NC_017537_3	3.26\|559322\|35\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559322-559356	35	JQ011317	Escherichia phage TL-2011b, complete genome	37437-37471	9	0.743

1. spacer 3.7|558084|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_009813 (Listeria phage B054, complete genome) position: , mismatch: 0, identity: 1.0

caacgctttttattgatatgatactatatgacatta	CRISPR spacer
caacgctttttattgatatgatactatatgacatta	Protospacer
************************************

2. spacer 3.13|558477|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to AJ312240 (Bacteriophage PSA complete genome) position: , mismatch: 0, identity: 1.0

acagtcaaatgatgatgaccaacttcctctgccaaag	CRISPR spacer
acagtcaaatgatgatgaccaacttcctctgccaaag	Protospacer
*************************************

3. spacer 3.7|558084|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to MH341453 (Listeria phage PSU-VKH-LP041, complete genome) position: , mismatch: 1, identity: 0.972

caacgctttttattgatatgatactatatgacatta	CRISPR spacer
caacgctttttattgatatgatactatatgacatca	Protospacer
**********************************.*

4. spacer 3.21|558998|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to DQ003637 (Listeria phage A500, complete genome) position: , mismatch: 1, identity: 0.972

ggttttaacttctaggttattttgtgcattttttgg	CRISPR spacer
ggttttaacttctaggttattttgtgcatgttttgg	Protospacer
***************************** ******

5. spacer 3.8|558149|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 2, identity: 0.946

tgcttcttgctgttctttctcttttttaagatttcat	CRISPR spacer
tgcttcttgctgttctttctcttttttaagattcaat	Protospacer
*********************************. **

6. spacer 3.13|558477|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.946

acagtcaaatgatgatgaccaacttcctctgccaaag	CRISPR spacer
acagtcaaatgatgatgaccaagttcctctgccaatg	Protospacer
********************** ************ *

7. spacer 3.13|558477|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 2, identity: 0.946

acagtcaaatgatgatgaccaacttcctctgccaaag	CRISPR spacer
acagtcaaatgatgatgaccaagttcctctgccaatg	Protospacer
********************** ************ *

8. spacer 3.19|558867|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 2, identity: 0.944

tatctttatctgtagctagtttgaaatcatcttcat	CRISPR spacer
tatcttcatctgtagctagtttaaaatcatcttcat	Protospacer
******.***************.*************

9. spacer 3.19|558867|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_003216 (Listeria phage A118, complete genome) position: , mismatch: 2, identity: 0.944

tatctttatctgtagctagtttgaaatcatcttcat	CRISPR spacer
tatcttcatctgtagctagtttaaaatcatcttcat	Protospacer
******.***************.*************

10. spacer 3.19|558867|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to AJ242593 (Bacteriophage A118 complete genome) position: , mismatch: 2, identity: 0.944

tatctttatctgtagctagtttgaaatcatcttcat	CRISPR spacer
tatcttcatctgtagctagtttaaaatcatcttcat	Protospacer
******.***************.*************

11. spacer 3.20|558932|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KJ094022 (Listeria phage LP-030-3, complete genome) position: , mismatch: 2, identity: 0.946

gaaagtaaagaaatcaagcctaaatttgttttccggt	CRISPR spacer
gaaagtaaagaaatcaagcctaaatttgttttccgac	Protospacer
***********************************..

12. spacer 3.21|558998|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KJ094022 (Listeria phage LP-030-3, complete genome) position: , mismatch: 2, identity: 0.944

ggttttaacttctaggttattttgtgcattttttgg	CRISPR spacer
tgttttaacttctaggttattttgtgcatgttttgg	Protospacer
 **************************** ******

13. spacer 3.21|558998|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to MH341452 (Listeria phage PSU-VKH-LP040, complete genome) position: , mismatch: 2, identity: 0.944

ggttttaacttctaggttattttgtgcattttttgg	CRISPR spacer
ggttttaacttctaggttattttgtgcatgtttcgg	Protospacer
***************************** ***.**

14. spacer 3.21|558998|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KP399678 (Listeria phage vB_LmoS_293, complete genome) position: , mismatch: 2, identity: 0.944

ggttttaacttctaggttattttgtgcattttttgg	CRISPR spacer
ggttttaacttctaggttattttgtgcatgtttcgg	Protospacer
***************************** ***.**

15. spacer 3.24|559191|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to MH341452 (Listeria phage PSU-VKH-LP040, complete genome) position: , mismatch: 2, identity: 0.944

ttttcaatgtgcgagtatgctcctctggaaattcct	CRISPR spacer
ttttcaatatgcgagtaagctcctctggaaattcct	Protospacer
********.******** ******************

16. spacer 3.24|559191|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to DQ003637 (Listeria phage A500, complete genome) position: , mismatch: 2, identity: 0.944

ttttcaatgtgcgagtatgctcctctggaaattcct	CRISPR spacer
ttttcaatgtgtgagtatgctcctctagaaattcct	Protospacer
***********.**************.*********

17. spacer 3.13|558477|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 3, identity: 0.919

acagtcaaatgatgatgaccaacttcctctgccaaag	CRISPR spacer
acagtcaaatgatgatgtccaacttcctctgctaatg	Protospacer
***************** **************.** *

18. spacer 3.8|558149|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 4, identity: 0.892

tgcttcttgctgttctttctcttttttaagatttcat	CRISPR spacer
cgcttcttgccgttctttctcttttttaagattcaat	Protospacer
.*********.**********************. **

19. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to JB137888 (Sequence 7 from Patent WO2012159774) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

20. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to KJ094025 (Listeria phage LP-032 contig 2, partial genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

21. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to MH299806 (Listeria phage LP-KV022, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

22. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to MN114083 (Listeria phage LP-013, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

23. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to NC_021785 (Listeria phage LP-110, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

24. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to MN128593 (Listeria phage LP-031, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

25. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to NC_021787 (Listeria phage LP-037, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

26. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

27. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to KJ094020 (Listeria phage LP-026, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

28. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to KJ094021 (Listeria phage LP-114, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

29. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to MN114082 (Listeria phage LP-010, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ttaaataaagcacctgtaaaagctaatgcaatcgga	Protospacer
 . **.******************************

30. spacer 3.27|559386|36|NC_017537|CRISPRCasFinder,CRT matches to JX442241 (Listeria phage P70, complete genome) position: , mismatch: 4, identity: 0.889

actaacaaagcacctgtaaaagctaatgcaatcgga	CRISPR spacer
ataaataaagcacctgtgaaagctaatgcaatcgga	Protospacer
*. **.***********.******************

31. spacer 3.8|558149|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to MK075006 (Staphylococcus phage phiSP119-3, complete genome) position: , mismatch: 7, identity: 0.811

tgcttcttgctgttctttctcttttttaagatttcat----	CRISPR spacer
tgcttcttgcttttctttctcttttt----gcttcattcga	Protospacer
*********** **************    ..*****

32. spacer 3.8|558149|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to AP019562 (Staphylococcus phage SP276 DNA, complete genome) position: , mismatch: 7, identity: 0.811

tgcttcttgctgttctttctcttttttaagatttcat----	CRISPR spacer
tgcttcttgcttttctttctcttttt----gcttcattcga	Protospacer
*********** **************    ..*****

33. spacer 3.8|558149|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to MK075003 (Staphylococcus phage phiSP44-1, complete genome) position: , mismatch: 7, identity: 0.811

tgcttcttgctgttctttctcttttttaagatttcat----	CRISPR spacer
tgcttcttgcttttctttctcttttt----gcttcattcga	Protospacer
*********** **************    ..*****

34. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to LC557520 (Staphylococcus phage vB_SsapH-Golestan101-M DNA, complete genome) position: , mismatch: 8, identity: 0.765

tttttttggctttttctttagacacttttaactt	CRISPR spacer
tttttttagctttttctttagatacacatttcct	Protospacer
*******.**************.** . *  *.*

35. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_030946 (Streptococcus phage phiARI0923, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

36. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KY065482 (Streptococcus phage IPP42, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

37. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KY065483 (Streptococcus phage IPP43, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

38. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KY065489 (Streptococcus phage IPP51, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

39. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KY065484 (Streptococcus phage IPP44, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

40. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KY065481 (Streptococcus phage IPP41, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

41. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_027396 (Streptococcus phage SpSL1, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

42. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to KY065449 (Streptococcus phage IPP5, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
ccatcttagctttttctttatacacttttaaagg	Protospacer
.. *.**.************ **********

43. spacer 3.1|557699|34|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to MN694145 (Marine virus AFVG_250M840, complete genome) position: , mismatch: 9, identity: 0.735

tttttttggctttttctttagacacttttaactt	CRISPR spacer
tattttcggcttcttctttagacactccattttt	Protospacer
* ****.*****.*************..   .**

44. spacer 3.26|559322|35|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to HC318808 (Sequence 63 from Patent WO2010000854) position: , mismatch: 9, identity: 0.743

taacaatgaaaaacggatttacaaaattagcgtcc	CRISPR spacer
tgacaatgcaatacggatttacaaaatcaaatgcg	Protospacer
*.****** ** ***************.*.   *

45. spacer 3.26|559322|35|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to HC318804 (Sequence 59 from Patent WO2010000854) position: , mismatch: 9, identity: 0.743

taacaatgaaaaacggatttacaaaattagcgtcc	CRISPR spacer
tgacaatgcaatacggatttacaaaatcaaatgcg	Protospacer
*.****** ** ***************.*.   *

46. spacer 3.26|559322|35|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to HC318806 (Sequence 61 from Patent WO2010000854) position: , mismatch: 9, identity: 0.743

taacaatgaaaaacggatttacaaaattagcgtcc	CRISPR spacer
tgacaatgcaatacggatttacaaaatcaaatgcg	Protospacer
*.****** ** ***************.*.   *

47. spacer 3.26|559322|35|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to JQ011317 (Escherichia phage TL-2011b, complete genome) position: , mismatch: 9, identity: 0.743

taacaatgaaaaacggatttacaaaattagcgtcc	CRISPR spacer
tgacaatgcaatacggatttacaaaatcaaatgcg	Protospacer
*.****** ** ***************.*.   *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

70213 : 110809

Listeria_phage(89.13%)

holin,integrase,portal,protease,capsid,terminase,tail

attL 71288:71332|attR 109693:109737

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012582203.1\|70213_71170_+	NAD(P)-binding domain-containing protein	M1H502	Paramecium_bursaria_Chlorella_virus	6.5e-31	29.9
71288:71332	attL	NA	NA	NA	NA
WP_012582202.1\|71437_72616_-\|integrase	site-specific integrase	A0A0B5CTW8	Listeria_phage	6.2e-116	55.3
WP_012582201.1\|72698_73247_-	hypothetical protein	NA	NA	NA	NA
WP_014588975.1\|73266_73779_-	ImmA/IrrE family metallo-endopeptidase	A0A1S7FYX8	Listeria_phage	1.5e-66	73.2
WP_012582200.1\|73802_74138_-	helix-turn-helix transcriptional regulator	A0A1S7FZ25	Listeria_phage	2.0e-32	64.2
WP_012582199.1\|74409_74613_+	helix-turn-helix domain-containing protein	A0A1S7FZ40	Listeria_phage	5.6e-17	68.8
WP_012582198.1\|74613_74799_+	helix-turn-helix domain-containing protein	A0A1S7FYV9	Listeria_phage	1.0e-17	71.9
WP_012582197.1\|75065_75332_+	hypothetical protein	A0A1S7FYW4	Listeria_phage	1.5e-25	74.4
WP_012582196.1\|75337_75595_+	hypothetical protein	Q8W5X5	Listeria_phage	3.9e-31	87.7
WP_014588976.1\|75612_75951_+	DUF3310 domain-containing protein	E2GLY2	Acinetobacter_phage	5.6e-14	52.0
WP_012582194.1\|75943_76174_+	hypothetical protein	A0A1S7FYX1	Listeria_phage	1.7e-14	57.9
WP_012582193.1\|76170_76386_+	hypothetical protein	NA	NA	NA	NA
WP_012582192.1\|76382_77135_+	hypothetical protein	A0A1S7FZ47	Listeria_phage	1.1e-09	34.3
WP_012582191.1\|77136_78318_+	DUF2800 domain-containing protein	A0A1S7FYX0	Listeria_phage	1.1e-173	75.6
WP_012582190.1\|78401_78983_+	DUF2815 family protein	A0A1S7FZ05	Listeria_phage	2.7e-64	73.1
WP_012582189.1\|79276_80914_+	DNA polymerase	A0A1S7FZ18	Listeria_phage	5.3e-259	80.2
WP_012582188.1\|80926_81151_+	hypothetical protein	NA	NA	NA	NA
WP_012582186.1\|81597_81984_+	hypothetical protein	M1PLH5	Streptococcus_phage	2.4e-08	32.8
WP_012582185.1\|81983_82253_+	hypothetical protein	NA	NA	NA	NA
WP_012582184.1\|82253_82625_+	hypothetical protein	NA	NA	NA	NA
WP_041176601.1\|82822_82990_+	hypothetical protein	NA	NA	NA	NA
WP_012582182.1\|82986_83421_+	hypothetical protein	A8ATD9	Listeria_phage	7.0e-33	56.3
WP_012582180.1\|83637_83820_+	hypothetical protein	NA	NA	NA	NA
WP_012582179.1\|83853_86292_+	virulence-associated E family protein	A0A1S7FZ15	Listeria_phage	0.0e+00	85.4
WP_012582178.1\|86597_86876_+	VRR-NUC domain-containing protein	A0A1S7FZ22	Listeria_phage	6.0e-30	74.2
WP_012582177.1\|86875_88267_+	DEAD/DEAH box helicase	A0A1S7FYY5	Listeria_phage	2.8e-216	80.2
WP_012582176.1\|88250_88616_+	nucleoside triphosphate pyrophosphohydrolase family protein	A0A1S7FYY8	Listeria_phage	1.0e-29	58.7
WP_012582175.1\|88615_89158_+	hypothetical protein	A0A1S7FZ07	Listeria_phage	1.8e-62	71.6
WP_041176473.1\|89295_89628_+	hypothetical protein	A0A060AG27	Listeria_phage	2.5e-38	65.8
WP_041176474.1\|89628_89937_+	HNH endonuclease	A0A1S7FZ53	Listeria_phage	2.5e-45	85.3
WP_003768814.1\|90059_90413_+\|terminase	P27 family phage terminase small subunit	A0A1S7FYW6	Listeria_phage	1.7e-45	80.3
WP_012582174.1\|90399_92046_+\|terminase	terminase large subunit	A0A1S7FZ68	Listeria_phage	1.4e-291	87.4
WP_012582173.1\|92057_93266_+\|portal	phage portal protein	A0A1S7FYX7	Listeria_phage	1.7e-193	84.9
WP_012582172.1\|93262_94093_+\|protease	Clp protease ClpP	A0A1S7FZ23	Listeria_phage	2.5e-103	71.4
WP_012582171.1\|94126_95272_+\|capsid	phage major capsid protein	A0A1S7FZ31	Listeria_phage	9.4e-186	86.3
WP_012582170.1\|95409_95706_+	hypothetical protein	A0A1S7FYY9	Listeria_phage	3.4e-31	68.4
WP_094153171.1\|95815_96022_+	hypothetical protein	A0A1S7FZ08	Listeria_phage	2.8e-24	79.1
WP_041176475.1\|96023_96425_+	hypothetical protein	A0A1S7FYZ7	Listeria_phage	2.8e-44	66.4
WP_012582169.1\|96411_96837_+	hypothetical protein	A0A1S7FZ20	Listeria_phage	3.6e-58	82.1
WP_012582168.1\|96852_97440_+	hypothetical protein	A0A1S7FZ79	Listeria_phage	9.3e-81	73.8
WP_012582167.1\|97450_97702_+	plasmid partitioning protein	NA	NA	NA	NA
WP_012582166.1\|97764_98136_+	hypothetical protein	A0A1S7FZ84	Listeria_phage	5.7e-44	69.9
WP_012582165.1\|98315_102710_+\|tail	phage tail tape measure protein	A0A1S7FYZ4	Listeria_phage	0.0e+00	69.7
WP_012582164.1\|102706_103615_+	hypothetical protein	A0A1S7FZ36	Listeria_phage	8.3e-137	80.3
WP_012582163.1\|103614_104640_+	hypothetical protein	A0A1S7FZ49	Listeria_phage	2.5e-158	78.0
WP_012582162.1\|104642_105413_+	hypothetical protein	A0A1S7FZ03	Listeria_phage	4.9e-114	74.2
WP_003768842.1\|105412_105712_+	hypothetical protein	A0A1S7FZ19	Listeria_phage	1.4e-24	56.3
WP_012582161.1\|105708_105870_+	hypothetical protein	NA	NA	NA	NA
WP_014588982.1\|105899_106121_+	hypothetical protein	NA	NA	NA	NA
WP_003768869.1\|106122_106533_+	hypothetical protein	NA	NA	NA	NA
WP_014588983.1\|106542_106797_+\|holin	phage holin	Q8W5Y9	Listeria_phage	5.1e-36	90.4
WP_012582159.1\|106796_107030_+	hypothetical protein	R4IBI3	Listeria_phage	7.8e-31	88.3
WP_012582158.1\|107032_107959_+	N-acetylmuramoyl-L-alanine amidase family protein	R4ICC5	Listeria_phage	1.0e-158	86.0
WP_014588984.1\|107983_108403_+	hypothetical protein	A0A0B5CTT3	Listeria_phage	1.2e-29	47.9
WP_012582157.1\|108451_108715_-	AcrIIA4 family anti-CRISPR protein	A0A2D0TCG7	unidentified_phage	4.2e-33	81.6
WP_012582156.1\|108939_109128_-	hypothetical protein	NA	NA	NA	NA
WP_012582155.1\|109159_109363_-	hypothetical protein	A8ATJ3	Listeria_phage	2.0e-22	77.3
WP_041176476.1\|109943_110270_+	hypothetical protein	NA	NA	NA	NA
109693:109737	attR	NA	NA	NA	NA
WP_003728958.1\|110305_110809_-	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	6.9e-08	42.9

DBSCAN-SWA_2

1196926 : 1297047

115

Listeria_phage(81.82%)

holin,tRNA,integrase,portal,protease,plate,capsid,terminase,tail

attL 1196128:1196144|attR 1291909:1291925

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1196128:1196144	attL	NA	NA	NA	NA
WP_012581500.1\|1196926_1197979_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.3e-29	34.9
WP_012581499.1\|1197978_1200387_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003729718.1\|1200548_1201250_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.6e-33	35.8
WP_012581497.1\|1201263_1204674_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_003729716.1\|1204771_1205224_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012581496.1\|1205239_1208440_+	MMPL family transporter	NA	NA	NA	NA
WP_012581495.1\|1208543_1209218_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	7.5e-50	47.7
WP_041176503.1\|1209255_1210182_-	ribonuclease HIII	NA	NA	NA	NA
WP_012581493.1\|1210335_1210599_+	cell division protein ZapA	NA	NA	NA	NA
WP_003729712.1\|1210598_1211141_+	CvpA family protein	NA	NA	NA	NA
WP_012581492.1\|1211233_1212946_+	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	1.5e-17	24.4
WP_012581491.1\|1212968_1215326_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.0e-21	50.4
WP_012581490.1\|1215407_1215719_+	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	7.0e-19	39.6
WP_012581489.1\|1215794_1217606_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_003729709.1\|1217799_1219014_+	aspartate kinase	NA	NA	NA	NA
WP_014598970.1\|1219071_1219566_-	YslB family protein	NA	NA	NA	NA
WP_012581487.1\|1219713_1220514_+	glutamate racemase	NA	NA	NA	NA
WP_003726032.1\|1220526_1221273_+	ribonuclease PH	NA	NA	NA	NA
WP_012581486.1\|1221276_1221888_+	XTP/dITP diphosphatase	NA	NA	NA	NA
WP_003726034.1\|1221924_1222449_+	metallophosphoesterase	NA	NA	NA	NA
WP_012581485.1\|1222734_1223889_-\|integrase	site-specific integrase	Q8W5Y3	Listeria_phage	6.7e-208	94.8
WP_003730990.1\|1224020_1224635_-	hypothetical protein	A0A059T7Z1	Listeria_phage	7.7e-78	77.0
WP_012581484.1\|1224685_1225138_-	ImmA/IrrE family metallo-endopeptidase	R4IBK9	Listeria_phage	8.2e-77	90.0
WP_012581483.1\|1225154_1225478_-	helix-turn-helix transcriptional regulator	A0A059T6G1	Listeria_phage	8.5e-36	71.0
WP_003730994.1\|1225877_1226081_-	hypothetical protein	NA	NA	NA	NA
WP_012581482.1\|1226147_1226339_+	helix-turn-helix transcriptional regulator	Q8W5X9	Listeria_phage	4.6e-21	86.9
WP_003730996.1\|1226360_1226603_+	hypothetical protein	A8ATD2	Listeria_phage	3.9e-41	93.8
WP_003730997.1\|1226605_1226791_+	hypothetical protein	A8ATD3	Listeria_phage	3.7e-28	98.4
WP_009929542.1\|1227025_1227178_+	hypothetical protein	A8ATD4	Listeria_phage	1.5e-19	100.0
WP_012581481.1\|1227314_1227602_+	hypothetical protein	A0A059T7V3	Listeria_phage	1.2e-44	94.7
WP_010991288.1\|1229579_1229768_+	hypothetical protein	NA	NA	NA	NA
WP_012581477.1\|1229764_1230058_+	hypothetical protein	A8ATM4	Listeria_phage	8.9e-32	78.4
WP_012581476.1\|1230074_1230473_+	hypothetical protein	A0A0B5CYR4	Listeria_phage	6.8e-35	56.4
WP_012581475.1\|1230473_1230644_+	hypothetical protein	A0A059T7N2	Listeria_phage	6.7e-24	94.4
WP_012581474.1\|1230643_1230832_+	hypothetical protein	D7RWG4	Brochothrix_phage	8.8e-09	45.0
WP_012581473.1\|1230828_1231284_+	pentapeptide repeat-containing protein	A0A060AFJ6	Listeria_phage	6.2e-40	85.9
WP_003727764.1\|1231280_1231466_+	hypothetical protein	A0A059T5G1	Listeria_phage	4.1e-27	100.0
WP_003769971.1\|1231462_1231753_+	hypothetical protein	Q8W5X0	Listeria_phage	2.2e-43	88.5
WP_012581472.1\|1231749_1231929_+	hypothetical protein	A8ATE3	Listeria_phage	5.8e-26	100.0
WP_012581471.1\|1231925_1232099_+	hypothetical protein	A0A059T5G3	Listeria_phage	3.4e-23	96.5
WP_012581470.1\|1232095_1232479_+	hypothetical protein	A8ATE8	Listeria_phage	1.6e-65	98.4
WP_012581469.1\|1232480_1232960_+	siphovirus Gp157 family protein	R4IBM0	Listeria_phage	7.4e-76	96.9
WP_010991282.1\|1232979_1233669_+	AAA family ATPase	R4IDY8	Listeria_phage	1.2e-130	100.0
WP_014589050.1\|1233732_1234989_+	DEAD/DEAH box helicase	R4IBK4	Listeria_phage	4.9e-220	95.0
WP_012581467.1\|1235011_1235497_+	DUF669 domain-containing protein	R4ICE5	Listeria_phage	5.1e-85	96.3
WP_012581466.1\|1235519_1237808_+	primase	A8ATF3	Listeria_phage	0.0e+00	91.3
WP_012581465.1\|1238141_1238459_+	VRR-NUC domain-containing protein	A8ATF4	Listeria_phage	2.1e-50	94.2
WP_003731659.1\|1238460_1238673_+	hypothetical protein	NA	NA	NA	NA
WP_012581464.1\|1239262_1239796_+	DUF3310 domain-containing protein	A8ATF5	Listeria_phage	8.7e-78	80.6
WP_009917712.1\|1239796_1240222_+	DUF722 domain-containing protein	A0A059T6H4	Listeria_phage	8.0e-74	100.0
WP_010991275.1\|1240319_1241063_+	DUF559 domain-containing protein	NA	NA	NA	NA
WP_012581463.1\|1241537_1241852_+	HNH endonuclease	A8ATF8	Listeria_phage	8.5e-57	98.1
WP_012581462.1\|1241957_1242257_+\|terminase	P27 family phage terminase small subunit	A8AT94	Listeria_phage	5.8e-39	83.8
WP_012581461.1\|1242253_1243894_+\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	2.7e-250	76.2
WP_012581460.1\|1243905_1245036_+\|portal	phage portal protein	A8AT96	Listeria_phage	9.8e-204	92.8
WP_012581459.1\|1245032_1245749_+\|protease	Clp protease ClpP	A0A1S5SFF8	Streptococcus_phage	1.0e-65	57.0
WP_012581458.1\|1245775_1246927_+\|capsid	phage major capsid protein	A8AT98	Listeria_phage	4.1e-213	98.7
WP_012581457.1\|1246933_1247104_+	hypothetical protein	A8AT99	Listeria_phage	1.2e-20	92.9
WP_003731645.1\|1247113_1247413_+	hypothetical protein	A8ATA0	Listeria_phage	5.3e-48	100.0
WP_003731644.1\|1247396_1247762_+	hypothetical protein	A8ATA1	Listeria_phage	1.3e-64	100.0
WP_003731643.1\|1247758_1248160_+	hypothetical protein	A8ATA2	Listeria_phage	2.1e-68	100.0
WP_012581456.1\|1248156_1248540_+	hypothetical protein	A8ATA3	Listeria_phage	3.8e-67	100.0
WP_012581455.1\|1248561_1249149_+\|tail	phage tail protein	A8ATA4	Listeria_phage	4.0e-108	100.0
WP_009917698.1\|1249219_1249552_+	hypothetical protein	A8ATA5	Listeria_phage	1.8e-52	99.1
WP_009917697.1\|1249602_1249752_+	hypothetical protein	A8ATA6	Listeria_phage	3.0e-20	100.0
WP_012581452.1\|1254684_1255515_+\|tail	phage tail family protein	A8ATA8	Listeria_phage	1.7e-157	100.0
WP_012581451.1\|1255524_1257117_+\|tail	phage tail protein	A8ATA9	Listeria_phage	1.2e-303	100.0
WP_012581450.1\|1257116_1257341_+	hypothetical protein	A8ATB0	Listeria_phage	1.5e-34	100.0
WP_012581449.1\|1257340_1259260_+	hypothetical protein	A8ATB1	Listeria_phage	0.0e+00	99.8
WP_014589054.1\|1259271_1260546_+\|plate	phage baseplate upper protein	A8ATB2	Listeria_phage	6.1e-218	96.5
WP_012581447.1\|1260562_1260883_+	hypothetical protein	A8ATB3	Listeria_phage	5.5e-27	81.1
WP_012581446.1\|1260883_1261030_+	XkdX family protein	A0A059T6D9	Listeria_phage	1.1e-19	100.0
WP_012581445.1\|1261055_1261511_+	hypothetical protein	A8ATB5	Listeria_phage	1.2e-67	100.0
WP_012581444.1\|1261477_1261873_+	hypothetical protein	A8ATB6	Listeria_phage	2.4e-64	100.0
WP_012581443.1\|1261885_1262134_+\|holin	phage holin	A8ATB7	Listeria_phage	1.4e-38	100.0
WP_012581442.1\|1262133_1262964_+	M15 family metallopeptidase	A8ATB8	Listeria_phage	2.3e-149	89.1
WP_012581441.1\|1263343_1263610_+	hypothetical protein	NA	NA	NA	NA
WP_041176506.1\|1263602_1263932_+	hypothetical protein	NA	NA	NA	NA
WP_012581439.1\|1263924_1264494_+	hypothetical protein	NA	NA	NA	NA
WP_012581438.1\|1264564_1265014_-	anti-CRISPR protein AcrIIA1	Q9T196	Listeria_phage	3.8e-74	97.3
WP_012581437.1\|1265018_1265369_-	AcrIIA2 family anti-CRISPR protein	Q9T195	Listeria_phage	1.2e-56	98.3
WP_012581436.1\|1265400_1265778_-	anti-CRISPR protein AcrIIA3	Q9T194	Listeria_phage	1.3e-67	99.2
WP_012581435.1\|1265883_1266093_-	hypothetical protein	A0A059T7Z0	Listeria_phage	8.0e-27	95.7
WP_012581433.1\|1266966_1267407_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_012581432.1\|1267860_1268271_+	Cys-Gln thioester bond-forming surface protein	NA	NA	NA	NA
WP_014589057.1\|1268313_1269987_+	hypothetical protein	NA	NA	NA	NA
WP_003736406.1\|1270299_1270719_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_003736407.1\|1270721_1270964_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012581430.1\|1271470_1271839_+	hypothetical protein	NA	NA	NA	NA
WP_014589058.1\|1271907_1272363_+	SUKH-3 domain-containing protein	NA	NA	NA	NA
WP_012581428.1\|1272577_1272940_+	hypothetical protein	NA	NA	NA	NA
WP_012581427.1\|1273607_1277297_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_012581426.1\|1277419_1278778_+	DUF1254 domain-containing protein	NA	NA	NA	NA
WP_003723540.1\|1278819_1279413_-	YdeI family protein	NA	NA	NA	NA
WP_012581425.1\|1279549_1279957_-	VOC family protein	NA	NA	NA	NA
WP_003723542.1\|1280121_1280721_+	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	2.9e-29	40.5
WP_003723543.1\|1280753_1281014_-	hypothetical protein	NA	NA	NA	NA
WP_012581424.1\|1281137_1282550_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.2e-51	32.1
WP_003730329.1\|1282574_1282838_+	DUF3116 family protein	NA	NA	NA	NA
WP_012581423.1\|1283003_1283480_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_003730327.1\|1283516_1283762_-	hypothetical protein	NA	NA	NA	NA
WP_012581422.1\|1283758_1284964_-	MFS transporter	NA	NA	NA	NA
WP_003726052.1\|1285168_1285828_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_003726053.1\|1285867_1286062_-	hypothetical protein	NA	NA	NA	NA
WP_003730323.1\|1286128_1286977_-	YitT family protein	NA	NA	NA	NA
WP_003723553.1\|1287307_1287445_-	hypothetical protein	NA	NA	NA	NA
WP_003736429.1\|1287595_1288309_+	trehalose operon repressor	NA	NA	NA	NA
WP_012581421.1\|1288339_1289986_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_003727531.1\|1290004_1291489_-	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_012581420.1\|1291606_1292068_+	NUDIX hydrolase	NA	NA	NA	NA
1291909:1291925	attR	NA	NA	NA	NA
WP_003726717.1\|1292106_1292571_-	hypothetical protein	NA	NA	NA	NA
WP_012581419.1\|1292759_1293674_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_012581418.1\|1293698_1294946_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.5e-107	52.3
WP_003736436.1\|1294929_1295760_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.2e-46	42.4
WP_012581417.1\|1295907_1297047_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_3

1846643 : 1854929

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012581151.1\|1846643_1847210_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	1.7e-26	39.1
WP_012581150.1\|1847206_1848256_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.1
WP_003722245.1\|1848274_1849702_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
WP_012581149.1\|1849686_1851906_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.6e-160	41.2
WP_012581148.1\|1851898_1852582_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003722248.1\|1852585_1852831_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_012581147.1\|1852842_1853556_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	6.1e-42	38.3
WP_003729814.1\|1853636_1854929_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_4

2529540 : 2537368

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003722604.1\|2529540_2530512_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
WP_012580771.1\|2530519_2531488_-	YvcK family protein	A1IMD5	Streptococcus_phage	8.8e-68	42.9
WP_003729205.1\|2531489_2532365_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
WP_012580770.1\|2532472_2534203_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.1e-174	53.5
WP_012580769.1\|2534230_2535292_-	galactose mutarotase	NA	NA	NA	NA
WP_003729208.1\|2535307_2536291_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	1.8e-52	38.4
WP_003739737.1\|2536408_2537368_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.5e-88	54.1

DBSCAN-SWA_5

2621870 : 2710600

105

Listeria_phage(83.58%)

holin,tRNA,portal,integrase,protease,plate,capsid,terminase,tail

attL 2653821:2653835|attR 2708063:2708077

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012580731.1\|2621870_2623541_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_003723610.1\|2623537_2623987_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_012580730.1\|2624064_2624718_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_077904926.1\|2624752_2624977_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_012580729.1\|2625011_2626334_-	HD domain-containing protein	A0A1B1ISR1	uncultured_Mediterranean_phage	5.8e-30	32.7
WP_012580728.1\|2626348_2627185_-	lipoyl-[GcvH]:protein N-lipoyltransferase	NA	NA	NA	NA
WP_003729274.1\|2627503_2627704_-	hypothetical protein	NA	NA	NA	NA
WP_003729275.1\|2627726_2628050_-	YxeA family protein	NA	NA	NA	NA
WP_012580727.1\|2628203_2629865_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003726112.1\|2629999_2630614_-	SdpI family protein	NA	NA	NA	NA
WP_012580726.1\|2630637_2631270_-	nicotinamidase	NA	NA	NA	NA
WP_003726114.1\|2631270_2631795_-	dihydrofolate reductase	NA	NA	NA	NA
WP_012580725.1\|2631797_2632796_-	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_003729280.1\|2632892_2633165_-	hypothetical protein	NA	NA	NA	NA
WP_003729281.1\|2633213_2634125_-	cation transporter	NA	NA	NA	NA
WP_012580724.1\|2634292_2635120_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_012580723.1\|2635234_2636107_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_012580722.1\|2636119_2636410_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_012580721.1\|2636457_2638542_-	LapB repeat-containing protein	NA	NA	NA	NA
WP_012580719.1\|2638949_2641271_-	InlB B-repeat-containing protein	NA	NA	NA	NA
WP_003729288.1\|2641622_2642294_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-36	40.2
WP_012580718.1\|2642293_2643382_-	ABC transporter permease	NA	NA	NA	NA
WP_012580717.1\|2643460_2644840_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	4.0e-58	48.3
WP_012580716.1\|2644836_2645514_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.4e-58	48.6
WP_012580715.1\|2645560_2646346_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_012580714.1\|2646407_2646884_-	DUF1641 domain-containing protein	NA	NA	NA	NA
WP_012580713.1\|2646883_2649871_-	formate dehydrogenase subunit alpha	NA	NA	NA	NA
WP_012580712.1\|2650368_2651211_+	S-adenosyl-l-methionine hydroxide adenosyltransferase family protein	NA	NA	NA	NA
WP_012580711.1\|2651260_2652742_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_003728385.1\|2652842_2653730_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
2653821:2653835	attL	NA	NA	NA	NA
WP_012582427.1\|2659523_2660552_-	P-loop NTPase	NA	NA	NA	NA
WP_012582426.1\|2660820_2662347_+	GW domain-containing glycosaminoglycan-binding protein	A0A0K2CP65	Brevibacillus_phage	1.2e-26	48.7
WP_012582425.1\|2662389_2663241_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.8e-48	37.6
WP_012582424.1\|2663262_2663685_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_012582423.1\|2663806_2664169_-	hypothetical protein	NA	NA	NA	NA
WP_012582422.1\|2664412_2665282_+	DUF4969 domain-containing protein	NA	NA	NA	NA
WP_012582421.1\|2665878_2666313_-	hypothetical protein	A0A0B5CTT3	Listeria_phage	1.2e-80	100.0
WP_012582420.1\|2666331_2667276_-	N-acetylmuramoyl-L-alanine amidase	Q8W5Y8	Listeria_phage	9.5e-168	91.7
WP_012582419.1\|2667268_2667529_-\|holin	phage holin	Q8W5Y9	Listeria_phage	1.6e-40	100.0
WP_012582418.1\|2667549_2667954_-	hypothetical protein	Q8W5Z0	Listeria_phage	2.8e-44	90.3
WP_003743972.1\|2667932_2668376_-	hypothetical protein	Q8W5Z1	Listeria_phage	8.0e-77	100.0
WP_012582417.1\|2668412_2668571_-	hypothetical protein	Q9T1A1	Listeria_phage	2.5e-12	78.8
WP_012582416.1\|2668575_2668854_-	hypothetical protein	A8ATB3	Listeria_phage	7.6e-17	56.8
WP_012582415.1\|2668850_2669936_-\|plate	BppU family phage baseplate upper protein	A0A059T7W9	Listeria_phage	2.4e-82	95.7
WP_012582414.1\|2669932_2670958_-	hypothetical protein	A0A0B5D157	Listeria_phage	1.3e-173	90.9
WP_012582413.1\|2670958_2671981_-\|tail	phage tail protein	A0A0B5D0G3	Listeria_phage	5.4e-193	98.5
WP_012582412.1\|2671995_2672823_-\|tail	phage tail family protein	A0A059T6D8	Listeria_phage	1.1e-154	96.7
WP_012582411.1\|2672819_2678186_-	tape measure protein	Q9T1A7	Listeria_phage	0.0e+00	95.6
WP_003735024.1\|2678196_2678796_-	bacteriophage Gp15 family protein	A0A0B5CTW0	Listeria_phage	1.9e-76	72.0
WP_003769943.1\|2678801_2679224_-\|tail	phage tail assembly chaperone	Q9T1A9	Listeria_phage	5.9e-69	97.9
WP_012582410.1\|2679278_2679518_-	Ig-like domain-containing protein	A0A059T5E4	Listeria_phage	5.2e-22	75.9
WP_012582409.1\|2679540_2679978_-	hypothetical protein	A0A0B5CYN3	Listeria_phage	4.2e-78	98.6
WP_012582408.1\|2679980_2680388_-\|capsid	minor capsid protein	A8ASK1	Listeria_phage	5.9e-66	98.5
WP_012582407.1\|2680387_2680726_-\|capsid	minor capsid protein	A8ASK0	Listeria_phage	3.2e-57	98.2
WP_012582406.1\|2680725_2681088_-	hypothetical protein	Q9T1B4	Listeria_phage	1.5e-60	94.2
WP_010990219.1\|2681087_2681483_-	hypothetical protein	A0A059T5E3	Listeria_phage	6.7e-67	99.2
WP_012582405.1\|2681501_2682503_-	hypothetical protein	A0A059T6D4	Listeria_phage	1.4e-185	99.4
WP_012582404.1\|2682502_2683093_-	phage scaffolding protein	Q9T1B8	Listeria_phage	9.1e-76	92.0
WP_012582403.1\|2683171_2684311_-\|capsid	phage minor capsid protein	A0A0B5D147	Listeria_phage	3.8e-203	96.6
WP_012582402.1\|2684311_2686081_-\|portal	phage portal protein	A0A059T657	Listeria_phage	1.8e-265	95.5
WP_012582401.1\|2686093_2687425_-\|terminase	PBSX family phage terminase large subunit	A8ASJ2	Listeria_phage	3.1e-249	94.4
WP_012582400.1\|2687393_2687936_-\|terminase	terminase small subunit	A8ASJ1	Listeria_phage	5.4e-91	98.9
WP_012582399.1\|2687974_2688274_-	hypothetical protein	A0A2H4JBC0	uncultured_Caudovirales_phage	6.5e-14	38.4
WP_003735131.1\|2688847_2689282_-	hypothetical protein	A8ASQ1	Listeria_phage	4.3e-75	99.3
WP_012582398.1\|2689300_2689465_-	hypothetical protein	A8ASQ0	Listeria_phage	2.5e-20	94.4
WP_012582397.1\|2689593_2689977_-	DUF2481 family protein	A0A0B5CYS3	Listeria_phage	4.4e-63	98.4
WP_014589139.1\|2689980_2690385_-	DUF1064 domain-containing protein	A8ASP7	Listeria_phage	1.6e-60	88.8
WP_033533856.1\|2690329_2690512_-	hypothetical protein	A8ASP6	Listeria_phage	8.5e-17	79.4
WP_012582394.1\|2690529_2691072_-	HNH endonuclease	A0A1W6JNP0	Staphylococcus_phage	7.1e-43	52.7
WP_012582393.1\|2691087_2691567_-	single-stranded DNA-binding protein	A0A059T5E0	Listeria_phage	4.8e-75	89.4
WP_012582392.1\|2691563_2691965_-	hypothetical protein	A8ATZ6	Listeria_phage	3.9e-54	82.0
WP_012582391.1\|2691976_2692204_-	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	3.9e-35	97.3
WP_012582390.1\|2692196_2692397_-	hypothetical protein	NA	NA	NA	NA
WP_012582389.1\|2692393_2692594_-	hypothetical protein	A8ASP4	Listeria_phage	6.5e-18	74.6
WP_012582388.1\|2692615_2692999_-	hypothetical protein	A8ATZ3	Listeria_phage	1.5e-55	90.6
WP_012582387.1\|2692995_2693457_-	hypothetical protein	D9J0I6	Brochothrix_phage	8.2e-16	33.1
WP_012582386.1\|2693453_2693627_-	hypothetical protein	A0A059T7N2	Listeria_phage	4.7e-25	93.0
WP_012582385.1\|2693627_2694017_-	hypothetical protein	A0A0B5CYR4	Listeria_phage	3.8e-30	54.6
WP_012581477.1\|2694033_2694327_-	hypothetical protein	A8ATM4	Listeria_phage	8.9e-32	78.4
WP_010991288.1\|2694323_2694512_-	hypothetical protein	NA	NA	NA	NA
WP_010991289.1\|2694504_2694903_-	hypothetical protein	A0A0B5CYQ9	Listeria_phage	3.4e-66	92.9
WP_014589047.1\|2694899_2696180_-	DNA (cytosine-5-)-methyltransferase	A0A1X9I6Y5	Streptococcus_phage	8.4e-119	54.6
WP_012582382.1\|2696486_2696774_-	hypothetical protein	A0A059T7V3	Listeria_phage	4.4e-44	93.7
WP_012582381.1\|2696770_2697691_-	DnaD domain-containing protein	A0A0B5D175	Listeria_phage	2.1e-140	90.5
WP_012582380.1\|2697711_2698527_-	recombinase RecT	A0A0B5CTU3	Listeria_phage	5.9e-150	99.3
WP_010991174.1\|2698526_2699486_-	YqaJ viral recombinase family protein	A8ATY5	Listeria_phage	1.3e-177	99.4
WP_003731815.1\|2699718_2699907_-	hypothetical protein	A0A0B5CU43	Listeria_phage	1.7e-28	98.4
WP_003734955.1\|2699922_2700213_-	hypothetical protein	A0A0B5CYM2	Listeria_phage	1.0e-48	100.0
WP_012582379.1\|2700237_2700771_-	hypothetical protein	A0A0B5CU01	Listeria_phage	1.2e-82	93.2
WP_012582378.1\|2700895_2701684_-	phage antirepressor Ant	Q9T178	Listeria_phage	1.4e-135	93.1
WP_012582377.1\|2701695_2701971_-	hypothetical protein	A8ASM5	Listeria_phage	2.7e-38	83.0
WP_012582376.1\|2701999_2702281_-	hypothetical protein	A0A0B5D168	Listeria_phage	1.2e-46	97.8
WP_003735007.1\|2702292_2702487_-	hypothetical protein	A0A059T6E5	Listeria_phage	1.3e-26	100.0
WP_003727743.1\|2702710_2702977_-	hypothetical protein	A0A059T7Q1	Listeria_phage	2.5e-41	100.0
WP_012582375.1\|2702997_2703231_-	helix-turn-helix transcriptional regulator	A8ASM3	Listeria_phage	1.6e-31	95.9
WP_012582374.1\|2703392_2703869_+	helix-turn-helix transcriptional regulator	A8ASM2	Listeria_phage	2.2e-56	78.9
WP_012582373.1\|2704024_2704192_+	hypothetical protein	NA	NA	NA	NA
WP_012582372.1\|2704246_2704852_+	hypothetical protein	NA	NA	NA	NA
WP_003770015.1\|2704913_2705789_+	hypothetical protein	A0A0B5D0D1	Listeria_phage	2.2e-150	94.5
WP_012582371.1\|2705856_2707050_+\|integrase	site-specific integrase	A0A0B5CTZ4	Listeria_phage	2.2e-217	100.0
WP_003726075.1\|2707135_2707528_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_003727703.1\|2707549_2707987_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_012582370.1\|2708181_2708928_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
2708063:2708077	attR	NA	NA	NA	NA
WP_003728530.1\|2708933_2709731_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_003727701.1\|2709733_2710600_-	energy-coupling factor ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.5e-10	25.5

Anti-CRISPR protein detection

Acr_ID: NC_017537.1|WP_012582157.1|108451_108715_-|AcrIIA4-family-anti-CRISPR-protein

Click the colored protein region to show detailed information

Acr_ID: NC_017537.1|WP_012581432.1|1267860_1268271_+|Cys-Gln-thioester-bond-forming-surface-protein

Click the colored protein region to show detailed information

Acr_ID: NC_017537.1|WP_003726053.1|1285867_1286062_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_017537.1|WP_003723553.1|1287307_1287445_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_017537.1|WP_012582373.1|2704024_2704192_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_017537.1|WP_012582372.1|2704246_2704852_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_017537.1|WP_003735007.1|2702292_2702487_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_017537.1|WP_003727743.1|2702710_2702977_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_017537.1|WP_012582157.1|108451_108715_-|AcrIIA4-family-anti-CRISPR-protein

108451_108715_-

87 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|14	0.8160919540229885	1	1.0

70213-110809

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.11\|558345\|37\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558345-558381	37	80818-80782	0

1. spacer 3.11|558345|37|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 80818-80782, mismatch: 0

atctacagaactctccgactcttgcacttccgtgata	CRISPR spacer
atctacagaactctccgactcttgcacttccgtgata	Protospacer
*************************************

NC_017537.1|WP_012581432.1|1267860_1268271_+|Cys-Gln-thioester-bond-forming-surface-protein

1267860_1268271_+

136 aa aa

1196926-1297047

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.19\|558867\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558867-558902	36	1265069-1265104	2

1. spacer 3.19|558867|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 1265069-1265104, mismatch: 2

tatctttatctgtagctagtttgaaatcatcttcat	CRISPR spacer
tatcttcatctgtagctagtttaaaatcatcttcat	Protospacer
******.***************.*************

NC_017537.1|WP_003726053.1|1285867_1286062_-|hypothetical-protein

1285867_1286062_-

64 aa aa

1196926-1297047

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.19\|558867\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558867-558902	36	1265069-1265104	2

1. spacer 3.19|558867|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 1265069-1265104, mismatch: 2

tatctttatctgtagctagtttgaaatcatcttcat	CRISPR spacer
tatcttcatctgtagctagtttaaaatcatcttcat	Protospacer
******.***************.*************

NC_017537.1|WP_003723553.1|1287307_1287445_-|hypothetical-protein

1287307_1287445_-

45 aa aa

1196926-1297047

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.19\|558867\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	558867-558902	36	1265069-1265104	2

1. spacer 3.19|558867|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 1265069-1265104, mismatch: 2

tatctttatctgtagctagtttgaaatcatcttcat	CRISPR spacer
tatcttcatctgtagctagtttaaaatcatcttcat	Protospacer
******.***************.*************

NC_017537.1|WP_012582373.1|2704024_2704192_+|hypothetical-protein

2704024_2704192_+

55 aa aa

2621870-2710600

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.24\|559191\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559191-559226	36	2703499-2703464	2

1. spacer 3.24|559191|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 2703499-2703464, mismatch: 2

ttttcaatgtgcgagtatgctcctctggaaattcct	CRISPR spacer
ttttcaatatgcgagtaagctcctctggaaattcct	Protospacer
********.******** ******************

NC_017537.1|WP_012582372.1|2704246_2704852_+|hypothetical-protein

2704246_2704852_+

201 aa aa

2621870-2710600

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.24\|559191\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559191-559226	36	2703499-2703464	2

1. spacer 3.24|559191|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 2703499-2703464, mismatch: 2

ttttcaatgtgcgagtatgctcctctggaaattcct	CRISPR spacer
ttttcaatatgcgagtaagctcctctggaaattcct	Protospacer
********.******** ******************

NC_017537.1|WP_003735007.1|2702292_2702487_-|hypothetical-protein

2702292_2702487_-

64 aa aa

2621870-2710600

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.24\|559191\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559191-559226	36	2703499-2703464	2

1. spacer 3.24|559191|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 2703499-2703464, mismatch: 2

ttttcaatgtgcgagtatgctcctctggaaattcct	CRISPR spacer
ttttcaatatgcgagtaagctcctctggaaattcct	Protospacer
********.******** ******************

NC_017537.1|WP_003727743.1|2702710_2702977_-|hypothetical-protein

2702710_2702977_-

88 aa aa

2621870-2710600

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017537_3	Unclear	3.24\|559191\|36\|NC_017537\|PILER-CR,CRISPRCasFinder,CRT	559191-559226	36	2703499-2703464	2

1. spacer 3.24|559191|36|NC_017537|PILER-CR,CRISPRCasFinder,CRT matches to NC_017537 position: 2703499-2703464, mismatch: 2

ttttcaatgtgcgagtatgctcctctggaaattcct	CRISPR spacer
ttttcaatatgcgagtaagctcctctggaaattcct	Protospacer
********.******** ******************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017537

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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