CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_015726	Cupriavidus necator N-1 chromosome 1, complete sequence	2 crisprs	c2c9_V-U4,DinG,csa3,DEDDh,WYL,cas3,RT	0	6
NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	0 crisprs	cas14j,PD-DExK,DEDDh,csa3	0	4
NC_015723	Cupriavidus necator N-1 chromosome 2, complete sequence	3 crisprs	DEDDh,c2c9_V-U4,csa3,DinG,RT,cas14j	1	0
NC_015724	Cupriavidus necator N-1 plasmid pBB2, complete sequence	0 crisprs	RT,c2c9_V-U4	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015726_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015726_1

1432689-1432783

Orphan

Consensus_repeat	Method
CGCGCCGGTGCCGGCGCTGGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015726_1

>merge|NC_015726|1|1432689-1432783|CRISPRCasFinder
CGCGCCGGTGCCGGCGCTGGCGCGCTACGGCGGGCGCCCGGTCTACTTCAGCGAATTCATCGTGCGTGCTGACGCGCCGGTGCAGGCGCTGGCGC

>NC_015726|1|1|1432689-1432783|CRISPRCasFinder
CGCGCCGGTGCCGGCGCTGGCGC	GCTACGGCGGGCGCCCGGTCTACTTCAGCGAATTCATCGTGCGTGCTGA
CGCGCCGGTGCAGGCGCTGGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015726.1\|WP_011615045.1\|1430142_1430412_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274645
NC_015726.1\|WP_013956407.1\|1430430_1431318_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176107
NC_015726.1\|WP_148271572.1\|1437517_1437709_+\|hypothetical-protein	unknown	unknown	unknown
NC_015726.1\|WP_013956401.1\|1422351_1423074_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380313
NC_015726.1\|WP_013956414.1\|1437955_1438774_+\|DUF2092-domain-containing-protein	unknown	unknown	gnl\|CDD\|378283
NC_015726.1\|WP_013956412.1\|1435267_1436164_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226605
NC_015726.1\|WP_011615043.1\|1427978_1428704_+\|(Fe-S)-binding-protein	unknown	unknown	gnl\|CDD\|223325
NC_015726.1\|WP_013956406.1\|1428733_1430146_+\|iron-sulfur-cluster-binding-protein	unknown	unknown	gnl\|CDD\|224062
NC_015726.1\|WP_013956418.1\|1441304_1442057_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NC_015726.1\|WP_148271571.1\|1423346_1424570_+\|D-alanyl-D-alanine-endopeptidase	unknown	unknown	gnl\|CDD\|236952
NC_015726.1\|WP_013956415.1\|1438785_1439271_+\|hypothetical-protein	unknown	unknown	unknown
NC_015726.1\|WP_013956410.1\|1433360_1434407_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270296
NC_015726.1\|WP_013956416.1\|1439324_1440359_-\|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235388
NC_015726.1\|WP_013956408.1\|1431469_1432471_+\|ornithine-cyclodeaminase-family-protein	unknown	unknown	gnl\|CDD\|225280
NC_015726.1\|WP_013956405.1\|1426957_1427743_-\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NC_015726.1\|WP_013956417.1\|1440447_1441236_-\|arginyltransferase	unknown	unknown	gnl\|CDD\|234939
NC_015726.1\|WP_013956404.1\|1426066_1426816_-\|FadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225097
NC_015726.1\|WP_013956413.1\|1436339_1437317_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|225531
NC_015726.1\|WP_013956411.1\|1434471_1435266_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224026
NC_015726.1\|WP_013956403.1\|1424638_1426051_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354

Protein	Function_ID	Function_description	E-value
NC_015726.1\|WP_011615045.1\|1430142_1430412_+\|hypothetical-protein	gnl\|CDD\|274645	TIGR03557, F420_G6P_family, F420-dependent oxidoreductase, G6PDH family. Members of this protein family include F420-dependent glucose-6-phosphate dehydrogenases (TIGR03554) and related proteins. All members of this family come from species that synthesize coenzyme F420, with the exception of those that belong to TIGR03885, a clade within this family in which cofactor binding may instead be directed to FMN. [Unknown function, Enzymes of unknown specificity].	0.00122307
NC_015726.1\|WP_013956407.1\|1430430_1431318_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176107	cd08415, PBP2_LysR_opines_like, The C-terminal substrate-domain of LysR-type transcriptional regulators involved in the catabolism of opines and that of related regulators, contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate-domain of LysR-type transcriptional regulators, OccR and NocR, involved in the catabolism of opines and that of LysR for lysine biosynthesis which clustered together in phylogenetic trees. Opines, such as octopine and nopaline, are low molecular weight compounds found in plant crown gall tumors that are produced by the parasitic bacterium Agrobacterium. There are at least 30 different opines identified so far. Opines are utilized by tumor-colonizing bacteria as a source of carbon, nitrogen, and energy. NocR and OccR belong to the family of LysR-type transcriptional regulators that positively regulates the catabolism of nopaline and octopine, respectively. Both nopaline and octopalin are arginine derivatives. In Agrobacterium tumefaciens, NocR regulates expression of the divergently transcribed nocB and nocR genes of the nopaline catabolism (noc) region. OccR protein activates the occQ operon of the Ti plasmid in response to octopine. This operon encodes proteins required for the uptake and catabolism of octopine. The occ operon also encodes the TraR protein, which is a quorum-sensing transcriptional regulator of the Ti plasmid tra regulon. LysR is the transcriptional activator of lysA gene encoding diaminopimelate decarboxylase, an enzyme that catalyses the decarboxylation of diaminopimelate to produce lysine. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.33264e-65
NC_015726.1\|WP_013956416.1\|1439324_1440359_-\|quinone-dependent-dihydroorotate-dehydrogenase	gnl\|CDD\|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	0
NC_015726.1\|WP_013956401.1\|1422351_1423074_+\|nitroreductase	gnl\|CDD\|380313	cd02136, PnbA_NfnB-like, nitroreductase similar to Mycobacterium smegmatis NfnB. Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.	1.87242e-41
NC_015726.1\|WP_013956414.1\|1437955_1438774_+\|DUF2092-domain-containing-protein	gnl\|CDD\|378283	pfam09865, DUF2092, Predicted periplasmic protein (DUF2092). This domain, found in various hypothetical prokaryotic proteins, has no known function.	4.4543e-87
NC_015726.1\|WP_013956412.1\|1435267_1436164_-\|ABC-transporter-permease	gnl\|CDD\|226605	COG4120, COG4120, ABC-type uncharacterized transport system, permease component [General function prediction only].	7.35099e-127
NC_015726.1\|WP_011615043.1\|1427978_1428704_+\|(Fe-S)-binding-protein	gnl\|CDD\|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	7.38771e-59
NC_015726.1\|WP_013956406.1\|1428733_1430146_+\|iron-sulfur-cluster-binding-protein	gnl\|CDD\|224062	COG1139, COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion].	0
NC_015726.1\|WP_148271571.1\|1423346_1424570_+\|D-alanyl-D-alanine-endopeptidase	gnl\|CDD\|236952	PRK11669, pbpG, D-alanyl-D-alanine endopeptidase; Provisional.	2.65757e-89
NC_015726.1\|WP_013956417.1\|1440447_1441236_-\|arginyltransferase	gnl\|CDD\|234939	PRK01305, PRK01305, arginyl-tRNA-protein transferase; Provisional.	2.49187e-142
NC_015726.1\|WP_013956410.1\|1433360_1434407_+\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	4.70463e-133
NC_015726.1\|WP_013956418.1\|1441304_1442057_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.37375e-134
NC_015726.1\|WP_013956408.1\|1431469_1432471_+\|ornithine-cyclodeaminase-family-protein	gnl\|CDD\|225280	COG2423, COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism].	3.28342e-104
NC_015726.1\|WP_013956405.1\|1426957_1427743_-\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	9.44872e-75
NC_015726.1\|WP_013956404.1\|1426066_1426816_-\|FadR-family-transcriptional-regulator	gnl\|CDD\|225097	COG2186, FadR, Transcriptional regulators [Transcription].	2.88108e-50
NC_015726.1\|WP_013956413.1\|1436339_1437317_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|225531	COG2984, COG2984, ABC-type uncharacterized transport system, periplasmic component [General function prediction only].	1.97809e-116
NC_015726.1\|WP_013956411.1\|1434471_1435266_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224026	COG1101, PhnK, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	3.1164e-147
NC_015726.1\|WP_013956403.1\|1424638_1426051_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	7.5512e-118

>NC_015726.1|WP_013956408.1|1431469_1432471_+|ornithine-cyclodeaminase-family-protein
MSDIHLTYINGKDIARLEMTDAEILDAVEQALVAQGNGQTVIEPRVHLIPDPAFNGHFNVLRGYVAPLGLAGVKIVGDFVDNYKLGLPSEMAMLNLFDPRTGMPVAMIDATFITDARTGALTALGAKHLARRNSKVLGHIGARGTSYWNVRLLDSLFDFDEIRVHSRRPESRNAFAARLERDLGKKIVVTEDWESCVRGADIVIEASRLERPTPMLKTEWIKPGAFIVPYGTMSAVELSLTDIMTRMVVDDWGQCKGGMFGSLRAHVEAGKLSEQTLYAELGEIVAGRKPGRQSDDETNLFWHRGLSLSDIALGHAILKKAESRGLGQRLLYA
>NC_015726.1|WP_013956407.1|1430430_1431318_-|LysR-family-transcriptional-regulator
MKMNLRQIEVFRAVMLTGSISGASKLLYVSQPAISRLMSHTEQRLGLELFRRTKGRLYPTPEARRLLGEVNAVYEGIERVNEIAEDLAANRTGSLRLTCSPNLGQTVLPRAIASFRAAHPAVRVVVRTQIPGNMLRALLSGQVDLAVSNMPLVHPNLEARLLVKNAIVALVPVDHRLATRSWVRPAELVGEDLIGYGPDVPFGLLVHEMFGSEGNQPDMRVQVEQAHVARALAQAGAGIALVDAMTVFGQSWPNIVAVPVRTKVNASVQIFHVQTEPLSRLSLEFVDTLTGMMKG
>NC_015726.1|WP_011615045.1|1430142_1430412_+|hypothetical-protein
MSAANNEALARMRAALDQHLAGSMPAGDLVRAWREAGTGLALPPVYGQAMEELLRRLEMSAVFAQDSCSFSSSAVTDQLTRWLDKAATV
>NC_015726.1|WP_013956406.1|1428733_1430146_+|iron-sulfur-cluster-binding-protein
MQVHSMEFKARAGQKLADQRLQQNLKKLSTKFVTARADAIRDIDFDATREALKERRNRALENLDVWLATFEENATRRGATVLFAETTADAARLVAEIAQKHGVKKVIKSKSMVTEEMRLNQVLGEMGVQSIETDLGEYILQINDSEPPSHIIAPVVHKDKDEIADLFARVHHKPRLTEIPEMTREAREVLRPEFLSADMGVTGGNFIIAETGSVAVVTNEGNEGMCTVMPRVHVAVTGIEKVLPTLEDLATVMRLLPRSATGQAISNYFSLLTGPRAEGERDGPEHMYFVLVDGGRTGLIGGDFQEMLRCIRCGACMNHCPVYQKIGGHAYGWVYPGPMGSVLTPSYVGLANAIDLPQAATMCGECNRVCPASIPLSDLLRKLREKQMERGLRPWQERFALQAWGYVAKRPELYAFATRIGAWLLGRMGGSNKLIASLPMAGKGWTETRDMPAPSGRTFRELYKERRARS
>NC_015726.1|WP_011615043.1|1427978_1428704_+|(Fe-S)-binding-protein
MRVGLFATCLVDLMRPEIGFSVLKLLEAAGYEVMVPEAQTCCGQPAYNSGERAVSRDLAEKFLREFEMFDYIVVPSGSCGGMIRQHYGDLLHNDPELNGRYERLRERVFELTDFLVNVARVQTLPSSFSGHVTYHDSCSGLRELGVKQQPRELLSRLPGVQLTEMKDCEACCGFGGTFSVKYGNISTAIVDEKCANIKASGADTVVLGDLGCILNIEGRLRRTGDSSTRVLHIAQVLAGDA
>NC_015726.1|WP_013956405.1|1426957_1427743_-|IclR-family-transcriptional-regulator
MSDADKSPGKTSIQVIERMMTLLDALAQHADPVSLKELSLATGLHPSTAHRILNDMVACRFVDRSDPGSYRLGMRLLELGNLVKARLSVRDAALAPMRALHRVTGQTVNLSVRQGDEIVYIERAYSERSGMQVVRAIGGRAPLHLTSVGKLFLAADEAARVRNYATRTGLAGHTRTSITDLTKLERELSWVRSNGYARDNEELELGVRCIAAGIYDDSRRLVAGLSLSAPADRLQDSWLQNLKDTALQISRGMGYVTEAAA
>NC_015726.1|WP_013956404.1|1426066_1426816_-|FadR-family-transcriptional-regulator
MRTRAVTLTEQVTRQLRADIENGTYPVGSRLPTGRQLAEQYGVSAAVIREVTEHLRSQGFVESRQGVGCTVRSRTGAAGFQLPREPDIDASGLADLYDLRIDLEGAAAALAAARRSDEDVAALSGLLQRLHAHLYDPQPAADIDAAFHIGIAAATHNPYYRQLLQYLNLQLHQAVATARANTLRQAGLAETVHAEHEAIVDAIRRGDAAAARAAAVTHLQCAARRLGLVLRTRADETSTARASSHPSLS
>NC_015726.1|WP_013956403.1|1424638_1426051_-|FAD-binding-oxidoreductase
MQTGQFAQRLTEALGADTVLTNPDDIAPWLSDWRGIYRGQAQAVLRPRTVDEVSRALALCQQAAVPVVPRGGNTGLCGGATPDAQAQNVVLSLDRMNAVRSLDTIANTMVAEAGCILGNLRRAAQDANRLLPLSLAAEDSCQIGGNLATNAGGVNVVRYGMARELVLGVEAVLPNGEVFHGLRTLRKDNTGYDLKQLLIGSEGTLGVITAAALRLFPRTDTRSVVLAAVASPAQSLALYELLFAQCGARLQAFEFFTGDCLDLVLTHAEGVQEPFAQRYPAYVLVELADTTDEAALNALLERVIGEALERELCLDAAVSASLAQLQALWKLREEISEAQRADGPHLKHDISLPIEQIPAFMTSMETRLRGLDPAIRPFIFGHFGDGNLHYNLSRPAGAPRDWAATQGDAVTDAVLDEVMRYGGSISAEHGIGQLKRHAFLAMKDPLELRLMREIKAVFDPAGIMNPGKLL
>NC_015726.1|WP_148271571.1|1423346_1424570_+|D-alanyl-D-alanine-endopeptidase
MFRSDSIFSRFFGSAPLSAVAAAVLVSVSMVAAPVALAATTSATTQKTPKKQAKSANAEKKSASKTVAKSSRGGKVAKSEASSTRKVVVLRNGKRHTVVAQRAAPVRAVFTPAKPSLGEAMGLRDTDDALALRSSVALVMDQNSNEVLFQKNASAVLPIASITKLMTALVVMDARLPMDEVLTISEDDRDTEKHSSSRLRFGTQLTRQELLLLALMSSENRAASALGRNYPGGLPAFVQAMNRKARELGMNDSHFVDSSGLSSSNVSSATDLVRMVNAAYRNPTIREFSTQTEHEVNVMGRTQHYVSTNRLVRGGNWEIGLQKTGFISEAGQCLVMQAKVQGRNVVMVFLDSAGKLSRFADANRVKEWLEHAPSPSSPQRGFPSSPNLTQAPGGAHAILASQQSRGI
>NC_015726.1|WP_013956401.1|1422351_1423074_+|nitroreductase
MNKMSHEVQFGSQDAVDCVDRAILTRRSVRAFLDTQVPRRTVEEILAVASRAPSGTNTQPWRVYVLSGEAKAKLCADVLCAYEDPERDSKYLEEYPYYPREWADPYLSRRRKVGWDLYGLLEISREDKARMHEQHARNFRFFDAPVGMIFTIDRIMEQGSWLDYGMFLQSIMVAARARGLDTCPQAAFTQFHKIIGSHLRLPPEEMVVCGMSLGFADPEAIENQLTTEREPVSEFARFLS
>NC_015726.1|WP_013956410.1|1433360_1434407_+|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKTAVKPDVEAAVKPAVNPVLRRMAMRCILACIAACAPWLAAAPALAQPPGYPAKPVRIVVPFAAGGPADVLGRAVGEGIAKATGQSVLVENKAGAAGTIGVDMVAKAAPDGYTLALVPVGNIAVNPTLMPNLPYKPADLAPVAMLATAENVLVVNAATPVKSLAELLKLAGQKPGELSFASPGAGSQAHLAGELLQLDAHVKLNHVPYKGISPAMTDVVGGQVTMMFAQMSAALPYIKAGKLRPLGVASAKRSAVLPDVPTIAEQGFPKFEALSWYALMAPAGTPAEIVRKLSQHVDAVLADATLKEKLATLGMEAAGGTPQQLATTIQKESTRWAGVIRQRHITID
>NC_015726.1|WP_013956411.1|1434471_1435266_-|ABC-transporter-ATP-binding-protein
MLRAQDLKLTFNPGTPIETRALRGLSLEIPSGQFVAVIGSNGAGKSTFLNAISGDQMVDSGRIAIDDTDVTRQPAWDRAQLVARVFQDPMAGTCEALTIEENMALAMARGSRRGFRPALNRVSRELFREKLRLLNLGLENRLTDRIGLLSGGQRQAVSLLMASLQPSRILLLDEHTAALDPKTAAFVLELTARIVEESKLTTMMVTHSMRQALDYGQRTVMLHQGQVVLDVSGDKRKGLDVPDLLKMFEQTRHEQLDDDALLLG
>NC_015726.1|WP_013956412.1|1435267_1436164_-|ABC-transporter-permease
MSLFSLLGALEIGLIFSLVALGVLISFRILNFPDLTVDGSFPLGGAVAATLIAAGQDPFVATAVAIAAGALAGFITGWLNVRLKIMDLLASILMMIALYSVNLRIMGRPNVPLITEPTLFTILQPEWLPDYVLRPLVLLVVVVVAKVGLDWFFSSQLGLAMRATGANPRMARSQGIPTGRATLAGMALSNALVALAGALFAQTQGGSDISMGIGTIVIGLAAVIIGETILPARRLIWTTLAVVLGAILYRFFIALALNSDFIGLKAQDLNLVTAALVTIALVLPATRKKLFARKNGGA
>NC_015726.1|WP_013956413.1|1436339_1437317_-|ABC-transporter-substrate-binding-protein
MKSIRGLAATKSILGGAVALALLYGGAVQAQTVKVLSIVDHPALDAIRDGVRAELKAAGYDADKSLKWEYQSAQGNTGTAAQIARKFVGDNPNAIVAIATPSAQAVVAATKTVPVVYSGVTDPVAAQLVKSWSASGTNVTGVSDKLPLDKQVALIKRVVPKAKTVGMVYNPGEANSVVVVKELKELLAKDGLTLKEAAAPRTVDIGPAAKSLIGKVDVIYTNTDNNVVSAYESLVKVANESKIPLVAADTDSVKRGAVAALGINYGDLGHQTGKVVVRILKGEKPGAIASQTSDNLELFVNTGAAAKQGVTLSPELVKEAKTVIK
>NC_015726.1|WP_148271572.1|1437517_1437709_+|hypothetical-protein
MDSHHAEVGHRMLSDARNPPSRRILLRGIHILLVDYPDCGGDIFMQLRDPGVEAFLDPWLSPA
>NC_015726.1|WP_013956414.1|1437955_1438774_+|DUF2092-domain-containing-protein
MYRVLSIAVLGVSLAACSSPAPTASAPVTQPASVQPAASTEPAAASKPAANAVDPAVIQALNNMGTYLSTLKRFSVDIDLDGERVLADGQKLQHSATAKVDIDRPNKMRAQMRSARAQRDLIYDGKTVTLYQPAQKYYASAGVTENLGDLIVHLRQRFGIEVPIGDLFLWGTPAAPVDNITSAMYAGSDYIDGTLCDHYALRQEAVDWQIWIASGSRPVPRKVVMTNRADEARPQSVTWLDWKLKPAFKDSVFHFTPPQGAREAKFVPLKTQ
>NC_015726.1|WP_013956415.1|1438785_1439271_+|hypothetical-protein
MKRVETSLLAVLGAVVLATYGWVPQAEARGGGHAAGRGGGGGGAQVSNVRADARTNNVRSASVNSVSANRNVNVNTNRNVNVNVDTHGGCCGGWDNDYHPVATAAAVTATVAVTAAVVGSVVRSVPPSCVPVSYGGMVYQQCGSTWYQPQGTQYVVVNAPY
>NC_015726.1|WP_013956416.1|1439324_1440359_-|quinone-dependent-dihydroorotate-dehydrogenase
MLNALYPLFRPALFSMDAEDAHHFTLNNLLRARRMGLGGCIGNKIADDPRTVMGVRFPNPVGLAAGLDKDGAYIDGLAALGFGSIEVGTVTPRAQPGNPRPRMFRLPQADALINRMGFNNGGVDAFVANVRASRWKAEGGVLGLNIGKNADTPIERANDDYLYCLERVYPHASYVTVNISSPNTKNLRQLQGASELDSLLSTLKDAQQRLADQHKRYVPLALKIAPDLDADQVGNIGDALVRHKIDGVIATNTTISREAVKGLPHAEEAGGLSGRPVFEASTRVVRALHGVVGDAVPIIGVGGIFGGADARAKIDAGAKLVQVYSGLIYRGPALVRECAAALRG
>NC_015726.1|WP_013956417.1|1440447_1441236_-|arginyltransferase
MSKLKELPLSALQFYATAPYACSYLDGRMARSQVATPAHLINADVYSRLVRAGFRRSGIFTYRPYCDECHACTPCRVVVDQFAPDRSQRRAWSRHQHLQALVAPLTYVEEHYSLYLLYQSMRHAGGGMDQDSRDQYEQFLLQSRVNSRLVEFREPPGSPEAGRLRMVSMIDVLDDGLSSVYTFYDPLERNASYGTYNILWQIRQTRELGLPHLYLGYWIADSRKMAYKARFRPLQVLTGNHWHAFEDEAGDTATAAPAPTRE
>NC_015726.1|WP_013956418.1|1441304_1442057_-|leucyl/phenylalanyl-tRNA--protein-transferase
MIAWLDPQDPFPPVAEALGPDSEAPGLLAASRDLSPQRLLLAYRQGIFPWYSSGQPVLWWSTDPRMVLPPSALRVSLNLRKTLRRVLRDADWEIRVDDDFLAVMRACATTPRDGQDGTWITDDIIAAYGTLHRNGMAHSVESWYRGERVGGLYGVALGRMFFGESMFAHRTDASKIALAALCAFLGNHGVAMIDCQQETDHLASLGARPIPRAEFVAHVRAATAQPAISPWRFDKSVLERWAGTPAAPAG

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Crispr_ID: NC_015726_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015726_2

3301504-3301612

Orphan

Consensus_repeat	Method
GTAGCCGCCGCGCTCTTCGGCCAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015726_2

>merge|NC_015726|2|3301504-3301612|CRISPRCasFinder
GTAGCCGCCGCGCTCTTCGGCCAGCAGCTTGAGCGAGTCTTGCGGCAGGATGCCACGGTCCCACAGCGAGCCTTCATAGGTGCTGTAGCGGCCGCGCTCTTCGGCCAGC

>NC_015726|2|2|3301504-3301612|CRISPRCasFinder
GTAGCCGCCGCGCTCTTCGGCCAGC	AGCTTGAGCGAGTCTTGCGGCAGGATGCCACGGTCCCACAGCGAGCCTTCATAGGTGCT
GTAGCGGCCGCGCTCTTCGGCCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015726.1\|WP_041228145.1\|3296628_3297252_-\|hypothetical-protein	unknown	unknown	unknown
NC_015726.1\|WP_041228469.1\|3287906_3288950_+\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238883
NC_015726.1\|WP_013958029.1\|3290054_3290951_-\|4-hydroxy-tetrahydrodipicolinate-synthase	unknown	unknown	gnl\|CDD\|188637
NC_015726.1\|WP_013958041.1\|3308592_3308898_-\|hypothetical-protein	unknown	unknown	unknown
NC_015726.1\|WP_013958044.1\|3311424_3311967_+\|hypoxanthine-guanine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181675
NC_015726.1\|WP_013958039.1\|3304842_3306465_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_015726.1\|WP_049800577.1\|3291269_3292244_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_015726.1\|WP_013958045.1\|3312014_3312629_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_015726.1\|WP_013958035.1\|3297518_3298361_+\|hypothetical-protein	unknown	unknown	unknown
NC_015726.1\|WP_013958032.1\|3293824_3295036_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_015726.1\|WP_013958031.1\|3292342_3293683_+\|D-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|235096
NC_015726.1\|WP_013958033.1\|3295070_3296594_+\|M81-family-metallopeptidase	unknown	unknown	gnl\|CDD\|227763
NC_015726.1\|WP_041228472.1\|3312735_3313164_-\|type-II-secretion-system-protein	unknown	unknown	gnl\|CDD\|225076
NC_015726.1\|WP_013958040.1\|3306490_3308596_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_015726.1\|WP_049800625.1\|3286463_3287288_-\|hypothetical-protein	unknown	unknown	unknown
NC_015726.1\|WP_013958047.1\|3313555_3313966_-\|general-secretion-pathway-protein-GspG	unknown	unknown	unknown
NC_015726.1\|WP_013958038.1\|3304228_3304846_-\|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD	unknown	unknown	gnl\|CDD\|236984
NC_015726.1\|WP_013958043.1\|3309975_3311370_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NC_015726.1\|WP_013958042.1\|3308904_3309843_-\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|226621
NC_015726.1\|WP_013958036.1\|3299478_3300663_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|235968

Protein	Function_ID	Function_description	E-value
NC_015726.1\|WP_041228469.1\|3287906_3288950_+\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238883	cd01847, Triacylglycerol_lipase_like, Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Members of this subfamily might hydrolyze triacylglycerol into diacylglycerol and fatty acid anions.	8.40624e-49
NC_015726.1\|WP_013958029.1\|3290054_3290951_-\|4-hydroxy-tetrahydrodipicolinate-synthase	gnl\|CDD\|188637	cd00950, DHDPS, Dihydrodipicolinate synthase (DHDPS). Dihydrodipicolinate synthase (DHDPS) is a key enzyme in lysine biosynthesis. It catalyzes the aldol condensation of L-aspartate-beta- semialdehyde and pyruvate to dihydropicolinic acid via a Schiff base formation between pyruvate and a lysine residue. The functional enzyme is a homotetramer consisting of a dimer of dimers. DHDPS is member of dihydrodipicolinate synthase family that comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways.	1.65262e-107
NC_015726.1\|WP_013958044.1\|3311424_3311967_+\|hypoxanthine-guanine-phosphoribosyltransferase	gnl\|CDD\|181675	PRK09162, PRK09162, hypoxanthine-guanine phosphoribosyltransferase; Provisional.	5.88518e-114
NC_015726.1\|WP_013958039.1\|3304842_3306465_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	5.16284e-170
NC_015726.1\|WP_049800577.1\|3291269_3292244_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.32707e-77
NC_015726.1\|WP_013958045.1\|3312014_3312629_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.7488e-27
NC_015726.1\|WP_013958031.1\|3292342_3293683_+\|D-serine-ammonia-lyase	gnl\|CDD\|235096	PRK02991, PRK02991, D-serine dehydratase; Provisional.	0
NC_015726.1\|WP_013958033.1\|3295070_3296594_+\|M81-family-metallopeptidase	gnl\|CDD\|227763	COG5476, COG5476, Uncharacterized conserved protein [Function unknown].	1.42429e-113
NC_015726.1\|WP_041228472.1\|3312735_3313164_-\|type-II-secretion-system-protein	gnl\|CDD\|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	0.00037791
NC_015726.1\|WP_013958040.1\|3306490_3308596_-\|PAS-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.26372e-24
NC_015726.1\|WP_013958032.1\|3293824_3295036_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.92338e-99
NC_015726.1\|WP_013958038.1\|3304228_3304846_-\|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD	gnl\|CDD\|236984	PRK11789, PRK11789, 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD.	6.71013e-123
NC_015726.1\|WP_013958043.1\|3309975_3311370_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NC_015726.1\|WP_013958042.1\|3308904_3309843_-\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|226621	COG4137, COG4137, ABC-type uncharacterized transport system, permease component [General function prediction only].	1.98055e-69
NC_015726.1\|WP_013958036.1\|3299478_3300663_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|235968	PRK07209, PRK07209, ribonucleotide-diphosphate reductase subunit beta; Validated.	0

>NC_015726.1|WP_013958036.1|3299478_3300663_-|ribonucleotide-diphosphate-reductase-subunit-beta
MLSWDDDVQATPQAAPQPALQPAVAATADQQGVLPPAATQPGILGDNPNAAAAQSNRRVNAADKRVINGSTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIIKRNLGFFVTADSLAANNIVLGTYRQITAPECRQYLLRQAFEEAIHTHAYQYIVESLGLNEAEIFNAYHEVQSIRDKDEFLIPFIDTLTDPSFKTGTPENDQKLLKSLIVFACIMEGLFFYVGFTQILAMGRQNKMTGAAEQYQYILRDESLHCNFGIDLINQIKLENPHLWTAEFKAEITELFKKAVDLEYRYAEDTMPRGVLGLNAPMFKGYLRFICNRRCQQIGLDQLFANEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWD
>NC_015726.1|WP_013958035.1|3297518_3298361_+|hypothetical-protein
MSVAAIYTEQQEWAANRGIAFDTRGYVPNLDLNLMRPLSPATFAAFANGDGGELVERGDKPAKMRALHSSSALAANIFDFWTDCADATPLMNALALPSCPTAALFESKLSTGLDSHANLDVCLPLANGIMAGLESKFTEWLRGKATQAGKAFRPPYLAQGRSRWEEVGLPRAQALAEALQAGREAFRHIGAPQLLKHALALARQYESRWVLRYVYFDWPGPHGERHRDEIRRFHELVGDELKFKAISYQAIFGELCSASRPEHQPYLAYLGGRYFRQPMG
>NC_015726.1|WP_041228145.1|3296628_3297252_-|hypothetical-protein
MFDLIDALLFDDAFVQLWEPQYDAIAHDEAEYQSVVQAVRKDVDSIDAIREATLRRILEWKSARTKGHVHWWNYGLYIETVRDCLSMHGDDRLDAICKLPGVRERVGSTILHFIYPDTYPIFDIRTLEALRYLGADLGKSFSVNNYYRFREYLISTQVELNRWTLRELDRAIFAFHKRSPEIFGATLGNGRRAQSTTHPHYCPRSGA
>NC_015726.1|WP_013958033.1|3295070_3296594_+|M81-family-metallopeptidase
MTSDQLPVRIAVAGLIHETNTYAAEFAGMTPLRAFEQHRGNEILAAFDKSNHQVGGFIEGARRSGATLIPTYVGQATPSGTIEAGAYAAMKHEILDGIRATLPVDGVLLALHGAGVADGTEDVEGDLALAVRALVGPGVPIAAVYDLHGNMTDAMRDACDLTLPCKLYPHTDFHDRGVEAVELLLEMIRGGLTPVTATRRLPMLPYIATTQEGFIPAEVNDVCRKLAAQPGVIDCSWFHGFPYADIAAPCPAVVCTTTGDAALAQRCADEVAQWIWSHREAFRPTFPPPAQGVALALSAAEGPVVVNEYADNPGGGTPGDGTHLLRALLDANPPAGTCCFASINDAAVVAQAQRAGVGATIRVSLGGKQGRFQGTPIEADAYVKCITDGRFVNRPGAMFEGVRFDLGAMCRLIIHGVDVIVASRAEQIYDVEPFALHGLDVTGYKLIAIKGANHFRAGYRTVAKQIISVDSEGLSTAAIASFPRERLVGEFWPLWDEVQFDGGADVA
>NC_015726.1|WP_013958032.1|3293824_3295036_+|MFS-transporter
MLCYVVAYLDRVNIGIAKLNMLADLQFSEAAYGLGAGLFFIGYMLFEVPSNLIMHRVGARRWIARIMISWGLLSGVMAFVTTPLQFYTVRFLLGVAEAGFYPGVILYLTYWFPNRRRAKVTAIFQAGIPIAGLLGSPLSGWILERFHLVGGHAGWQWVFVLEALPTLPLAIGVLWILTDRVKDAKWLTPAQRQLIENDIAQDDHGREHIPLTGILRDMRICKIILMTFPAMMALYTLGFYLPTLIKDAGAVSGVQIGLLSAIPYCVAVVAMVLVGRSSDRHGERRWHLASIMLVGAFGLVASVFAGQNLVLAVISLSIAAAGIISFSPIMWTLPTAFLGGATAAACIGAINSLANLGGFVSPYLIGWIRDTYHSTAPAIFIIAGALVASALIALSFDPKKVNR
>NC_015726.1|WP_013958031.1|3292342_3293683_+|D-serine-ammonia-lyase
MATLPLTRDLLAILQSRQPLLWLNPRLGQPLPASAPSTELIASAEARLARCAPLMATLFPELGSSHRQVESQLMPATALQHAIVGNDGAEGAWFIKRDDELPIAGSIKARGGFHEVLAIAESIAIEHGVLKPAGDRRLLATAAARALFSQYSVTVGSTGNLGLSIGVMAAALGFDAVVHMSADAKAWKKDRLRKRGVRVVEHEGDYAEAVAAGRDQALAAPRCHFVDDERSALLFFGYAAAARHLARQLAEAGRVVDAAHPLFIYLPCGVGGAPGGITYGLKALFGEHVHCFFAEPVASPCVLVQLASGAQAPVSVYDIGLDNRTDADGLAVGQASHLVSPLMASQLAGVFTVPDDQLYVQLLALKTSMGVEVEPSAAAGIGGPGWLRRSPEGQAYVRDHGLHMHDATHVIWATGGSLVPPEELRRFQDYAATLAGHASGAMQQAA
>NC_015726.1|WP_049800577.1|3291269_3292244_-|LysR-family-transcriptional-regulator
MRMQLDSSVLGALRCFEAAGRLLSFTKAAESLSLTQSAVSQQIRHLEDRLGYMLFVRQPRNLKLTPKGEAMFETTTRALHEIQQTIQRLGLPNAPLQVNCLPSYALQWLMPRLTEFHREQPDVSVRLKAEFQALDRQSMEAEDIDVAVRYDPVRYSQLQADVLLDEYLIPVATPEYLTQHPGLSDGASLDGVVLLHDASPWVGAAEFVEWRTWLEAFHPTWIGHLEGPQFNLSSLAISAALNHQGVAMGRTALVYDEIRSGRLVNVFGKHVRAPARYMLLSRNPEDRRVIIFSTWLKAECARFDTARMELLSLDGVPRRARLGR
>NC_015726.1|WP_013958029.1|3290054_3290951_-|4-hydroxy-tetrahydrodipicolinate-synthase
MQEVDYLYRGIWLPLVTPFRNHEVDHVALRRLVAHYRGSGLAGLVVCGSTGEAAALDEAEQLAVLDTVLAEAGELPVMMGLAGNNLRDVLSRLDRIGERPLAGVLAPAPYYIRPSQEGLKGYFRDLADRSTAPLVLYDIPYRTGVTLSAETLLSLANHGNIRGIKDCGGNAETTQALIADGRLAVLSGEDHQLLATLCMGGQGAIVASAHIRPDLFSALWRAVAEQRLSVARHLFHALIPLIRLMFAEPNPGPVKTLLARHGWLSDELRLPMTSASTALAEQLAIACDALDSVRANAL
>NC_015726.1|WP_041228469.1|3287906_3288950_+|SGNH/GDSL-hydrolase-family-protein
MKARHQSLFDLVRSGLLCVTVALFAACGGGDDGKPAVNPPLQFQVVSFGDSISDVGTYAPVAQLVGGGRFTTNPGQVWTQDVANFFGGTLTAAQTGGYGAPVRNHADGLGYAQGGARVTDPNGINFKANGLGALTVPIATQLQNHLSAHGNFNDGQLVLVQGGGSDILIHADAVVGGSETLGDANQAVTLAAQQLAAIVGKILQSGAKHVVVSNVGNIGVSPLGVSDNSLGSLLTGMTLTFNSALTNALQTAGIQNQVINIDQFGFINDVLAHFKEKGFQVSNTGTGCNLQLLSKEIEVSSLFCSPKTYTVPDADQTYMFADEVHPTTHLHALFATLVEQAVQAASK
>NC_015726.1|WP_049800625.1|3286463_3287288_-|hypothetical-protein
MLGDFSLQCLAQGDSWFSINTLRPFSGSNLLMNMWLSRSAIAVDCADPGDTLAHMLDSRQDPLFYSFLVGPHDQAWSVILLSGGGNDLIDAIQTTPNDANGHRRPPNDRLLLTEDEWDGPDAISTFISRPGWIAFTRYMLDQYRALDFLRRISAQNQNTPIITHTYDYATPRNSGAGLGRGPWLFPALQVYGIPEGNWIDLANEFTDRLADEVIRQAGIPNFHVAETRDTLDPAGTDDDGATADWENEIHPTADGYGKLGVKFVDKIAEVLHIP
>NC_015726.1|WP_013958038.1|3304228_3304846_-|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD
MSKPEHRYLPDADGWVPAARRVPSPNFDERPAGMPVDLVVLHNISLPPGQFGSGDIEAFFQNRLDPNKHPFFATIHQVQVSAHFLVTREGELVQFVPCTQRAWHAGQSDFFGRARCNDFSIGIEIEGCDDLPFTLAQYDTVAALVPALLVAYPVRAIAGHSDIAPGRKTDPGPHFDWARFARQAGVAPGMLPYQCPGAAGQVTNS
>NC_015726.1|WP_013958039.1|3304842_3306465_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MPPRMPRAPDPILVIDDEADLRELLDISIRRMGHDVVLAGSLAEAREKLAQGRYSLVLTDMRLGDGLGIEIVRQLSAAPERIPVAVITAYGSADNAVEALKAGAFDYIAKPVSLEQLRSLVLNALGRQQRDSTDAEAAAAEQAADRAAALLPGHSAAMQEVRRSLSRLARSMAPVVISGESGSGKERAARAIHATSGRAAHPFIAVNCGAIPENLMESEFFGHVKGAFTGADGERGGFFQAANGGTLLLDEVADLPLPMQVKLLRALQERRVRKIGASREDAVDVRVMCASHKDLAAMVAAGQFRQDLYYRLNVLALRMPTLRERGEDIPVLARAILDHLAVRYGDPRPKRLSPAALQRLVAYPFPGNVRELENLLERAYAFAESEEIELADLGPLDAGAERAGLMHAPAPAMAPNYYAPWGAAGMWAPVPPAAAPAPALAEPPPVAPTPASAPEPEPAGDPAERACRGIVFPIDLPARLEAVERELILQALAQTNFNRTAAAPLLGLNLRQLRYRIQQLGIREAMDAADRSAVEGEGTP
>NC_015726.1|WP_013958040.1|3306490_3308596_-|PAS-domain-containing-protein
MTEPASSGWQRLNAWRGLAQLWRQPEPPDFHWRLLRYFCWTRVAVGLLLVGFALMRRGEPASVTAVTNAIPPVPFDLGALGGIEHAAAMTIAVPYLGIALAMLAGTLWRRHFHLRVRVQVLADLALLALVFSVLGRGGQAEGLAMIFLLPALEAGALTSLLFALFAASISALVVMSGPFMHTILLRQADAGLLGSGLFGLVFMIAALLMYMLANRQIAQERLALAREQELRLQQLVNRLMVNDMQDGVMLVRANGAVVAANPAAVVLLGVQPHERIYSRRLGGAAGQGGEAVLFDLRRIPRLQPLMEMLRDWLHSKDDVPRILQLLPMASGTALADGTMQHTRLRLRFVLPGLAGLRSTMAHGRTVPATLDTAAWSELSPEAAGRLRLAIAQNEAMAWSQEDEALLRNEMRDTVLVHIESWERIAEQVQQEKLAAMGRLVASIAHQIRNPLAAISQASELLGDSGRRDPAAQDHGGADVDIDARLLRIINDNVRRLDQVVSDVLQMSRRPRTGRSTVHLAQALPEIVERWRAEMRSRRPRAGETRPAGRADINANAIRLTVDVAQPVVFDASQLQQVLGNLLDNAWRYCSRLPGSIRLLAHALDQHHAELIVWNDGAEVAREHQRSLFEPFFTSNAQGTGLGLFMARELCGANDAQVRYGAIALPALLERTGMLAPAARDTLPAKAFVLTLRIESADAAAA
>NC_015726.1|WP_013958041.1|3308592_3308898_-|hypothetical-protein
MARILILLAVVLGVIWWLRARAEARLAEHRARQARQAGERTGAAGPADDATAEPMVQCAQCGVHLPQGEAIAWRGLHYCRRSHLPDESRAEGGDGSSGPRP
>NC_015726.1|WP_013958042.1|3308904_3309843_-|cytochrome-c-biogenesis-protein-CcsA
MVIVLYALTALLYCGLAYHGWATRHPHVATAAGQAGGATSAVLVAGGGPIPPAGGAHGEGRPAWWHVLMLAALASHGLLLHETIFPAERMMFGFAFALSAMLWLGVGIYWIESFFFSLAGLGLIVIPVALVASLMPLAFPGSQILGYAARPLFKLHFIIANVAYGLFTLAAFHAFLMLLAERRLHGFRHAPARPPEQQPSEWLGRWLDLLPPLLTLEKLLFRLIGAGFVLLTLTIGSGLLFSEELFGRAFRLDHKTVFALISWAMFGGILAGRIFRGWRGKVALRWVIASFGILLLAYVGSRFVIEVVLHRL
>NC_015726.1|WP_013958043.1|3309975_3311370_+|signal-recognition-particle-protein
MLDNLTQRLARVVKTMRGEARLTEANTAEMLREVRLAMLEADVALPVVREFVARVKEKAMGEEVVSSLTPGQALVGVVQRELTAVIGGADAASGNNKEAELNLAVQPPAIILMAGLQGAGKTTTVGKLAKWLKENKKKKVLTVSCDVYRPAAIAQLKTVSEQVGADFFPSQPDQKPVDIARAAVDWARKHYHDVLIVDTAGRLGIDELMMQEIAALHAELKPAETLFVVDAMLGQDAVNTAKAFNDTLPLTGVVLTKLDGDARGGAALSVRHITGRPIKFVGVGEKLDGLEPFYPDRMAQRILGMGDILALVEEAQRGVDMEAAEKLAKKIKKTGDFDLEDFKAQIGQMKKMGGLGSLVDKLPAQFAQQAQGANMDQAEKQVARMEGIINSMTPTERAKPELIKASRKRRIAAGAGVPVQEVNRLLNQFDQMQSMMKKLKGGGMMKMMRQMGAMKGGMKGLFNR
>NC_015726.1|WP_013958044.1|3311424_3311967_+|hypoxanthine-guanine-phosphoribosyltransferase
MMSAVQARELWANSEEIVSAAEVQASLDRMATEITAKMGDAFPLVLSVMGGAVVFTGMLLPKLAFPLEFDYIHLSRYNNKTVGGEMQWRVAPRESVKDRVVLVLDDILDEGETMAAIRERIMDMGAREFHAAVLCEKTLTKIKPMHPDFCGFAVPDRYVFGCGMDAKGYWRNLDSIRALV
>NC_015726.1|WP_013958045.1|3312014_3312629_-|LysE-family-translocator
MEVSQLAAGTGVFAAFAGFALVSSITPGPNNTMLLASGVNFGFVRTVPHLLGVSIGFALMVGLVGLGLGSLFHAFPWTWQVLRVVATVYLIWLAWKLATAGGVQDQQVKRPMGFWAAAAFQWVNPKAWVMAVGACSTYVLHGNLLLNVLLLAGIFGVVNLPSVAMWALCGSALRRWLARPRVLRAFNIGMAVLLLASLWPILGA
>NC_015726.1|WP_041228472.1|3312735_3313164_-|type-II-secretion-system-protein
MGALVALAILGEMLSQFGVLWATQDRRAREADLLAHGNKIRRAIGAYYDANPAGQYPKRLDELVLDPRQPVVARYLRRAWRDPLPKGGEWGIVPGPDNGIVGVYSQAPGTPLRVGGFTPANAGFADKGSYQEWIFVHQPEAN
>NC_015726.1|WP_013958047.1|3313555_3313966_-|general-secretion-pathway-protein-GspG
MGTPEPSAELTVRRAQENELRRVLRELRKAIDDYKDAADAGKIQRKVGDSGYPPSLEALAEGVPDATDPGGERRLYFLRRLPRDPLCGCPDEPAARNWRLRSYQSPPDDPREGGVVFDVMSRNSGEALDGNHYDQW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

233860 : 281815

Salmonella_phage(15.38%)

tRNA,holin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013955325.1\|233860_234211_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_013955326.1\|234272_235103_+	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_013955327.1\|235111_235471_+	TfoX/Sxy family protein	NA	NA	NA	NA
WP_013955328.1\|235522_236281_+	Mut7-C ubiquitin/RNAse domain-containing protein	NA	NA	NA	NA
WP_013955329.1\|236440_237025_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_013955330.1\|237131_239084_+	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	1.2e-10	37.7
WP_013955331.1\|239190_240213_+	complex I NDUFA9 subunit family protein	NA	NA	NA	NA
WP_013955332.1\|240398_241097_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_013955333.1\|241153_242389_+	multifunctional CCA addition/repair protein	A0A0F6YPT7	Sinorhizobium_phage	1.1e-78	45.6
WP_013955334.1\|242385_242823_-	universal stress protein	NA	NA	NA	NA
WP_013955335.1\|242864_243698_-	ABC transporter ATP-binding protein	M1IC18	Acanthocystis_turfacea_Chlorella_virus	1.4e-08	30.9
WP_013955336.1\|243694_244441_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.1e-15	26.9
WP_148271556.1\|244437_245460_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_013955338.1\|245456_246353_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_041228274.1\|246378_247614_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013955340.1\|247855_249247_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_013955341.1\|249260_250289_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.4e-23	30.9
WP_049800586.1\|250300_251233_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_013955343.1\|251234_252089_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_013955344.1\|252098_252293_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_013955345.1\|252309_253497_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_080569529.1\|253512_254367_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_011614433.1\|254453_254855_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_013955347.1\|254964_255909_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	3.3e-104	70.9
WP_041227695.1\|255981_256809_-	hypothetical protein	NA	NA	NA	NA
WP_013955349.1\|257099_258464_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L277	Tupanvirus	5.4e-31	34.6
WP_013955350.1\|258581_260420_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	4.9e-144	45.3
WP_013955351.1\|261150_261780_+	cytochrome b/b6 domain-containing protein	NA	NA	NA	NA
WP_013955352.1\|261801_262575_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_041227697.1\|262639_262912_+	pentapeptide MXKDX repeat protein	NA	NA	NA	NA
WP_013955354.1\|263158_263596_+	hypothetical protein	NA	NA	NA	NA
WP_013955356.1\|264314_264950_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_049800573.1\|266497_267658_-\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	4.9e-134	60.3
WP_049800541.1\|267712_268012_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.5e-36	69.8
WP_013955359.1\|268082_269504_-\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	6.4e-83	37.5
WP_013955360.1\|269685_270627_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013955361.1\|270745_271738_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_013955362.1\|272032_272500_+	bacterioferritin	NA	NA	NA	NA
WP_013955363.1\|272980_273424_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013955364.1\|273448_274438_-	CDF family Co(II)/Ni(II) efflux transporter DmeF	NA	NA	NA	NA
WP_013955365.1\|274817_276278_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_013955366.1\|276607_277939_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_013955367.1\|278048_279566_+	CoA-acylating methylmalonate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_013955368.1\|279645_279996_+	VOC family protein	NA	NA	NA	NA
WP_013955369.1\|280002_280167_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_049800588.1\|280300_281461_-\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	3.8e-134	60.3
WP_049800541.1\|281515_281815_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.5e-36	69.8

DBSCAN-SWA_2

838353 : 847156

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013955853.1\|838353_839736_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.5e-70	36.7
WP_013955854.1\|839816_840764_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	5.5e-14	28.1
WP_013955855.1\|840792_841788_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	1.6e-27	32.4
WP_080569532.1\|841943_842330_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_013955857.1\|842567_843869_+	nitrate reductase	Q9KX94	Enterobacteria_phage	1.0e-143	64.8
WP_013955858.1\|844004_844907_+	cysteine synthase CysM	C3U2M1	Lactococcus_phage	1.7e-52	41.7
WP_013955859.1\|844976_846083_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_013955860.1\|846232_847156_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	1.0e-41	34.0

DBSCAN-SWA_3

1180918 : 1273211

102

Burkholderia_phage(16.13%)

tRNA,terminase,tail,integrase,protease,transposase,head,plate,holin,portal

attL 1189288:1189304|attR 1199081:1199097

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013956158.1\|1180918_1181584_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_013956159.1\|1181600_1182173_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_013956160.1\|1182310_1183195_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_013956161.1\|1183243_1184476_+	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_013956162.1\|1184543_1185332_+	MBL fold metallo-hydrolase	A0A2I7SDH3	Paenibacillus_phage	2.6e-25	31.6
WP_193351051.1\|1185870_1187076_-	cupin domain-containing protein	NA	NA	NA	NA
WP_041227837.1\|1187087_1187615_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_013956166.1\|1187696_1188746_-	hypothetical protein	NA	NA	NA	NA
WP_013956167.1\|1188742_1191373_-	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	1.0e-25	24.0
1189288:1189304	attL	NA	NA	NA	NA
WP_013956168.1\|1191617_1192898_+\|integrase	integrase family protein	C7BGE7	Burkholderia_phage	5.1e-140	57.0
WP_013956169.1\|1192905_1193160_-	hypothetical protein	NA	NA	NA	NA
WP_080569566.1\|1193162_1193636_-	DUF3850 domain-containing protein	A0A191SB19	Nostoc_phage	2.3e-05	44.4
WP_013956171.1\|1194021_1194300_-	DUF4031 domain-containing protein	A0A125RNQ7	Pseudomonas_phage	1.7e-24	69.8
WP_013956172.1\|1194296_1194578_-	hypothetical protein	NA	NA	NA	NA
WP_013956173.1\|1194570_1194819_-	hypothetical protein	NA	NA	NA	NA
WP_013956174.1\|1194811_1195441_-	hypothetical protein	NA	NA	NA	NA
WP_013956175.1\|1195443_1195914_-	hypothetical protein	NA	NA	NA	NA
WP_013956176.1\|1195910_1196666_-	hypothetical protein	R9TN97	Rhizobium_phage	8.5e-10	53.6
WP_013956177.1\|1196687_1198715_-	ParB N-terminal domain-containing protein	G8DH78	Emiliania_huxleyi_virus	5.6e-32	28.9
WP_013956178.1\|1198737_1199157_-	hypothetical protein	NA	NA	NA	NA
1199081:1199097	attR	NA	NA	NA	NA
WP_013956179.1\|1199153_1199513_-	hypothetical protein	NA	NA	NA	NA
WP_013956180.1\|1199523_1199754_-	hypothetical protein	NA	NA	NA	NA
WP_158310019.1\|1199755_1199893_-	hypothetical protein	NA	NA	NA	NA
WP_080569567.1\|1199889_1200111_-	AlpA family phage regulatory protein	C7BGF0	Burkholderia_phage	3.1e-21	68.6
WP_013956182.1\|1200110_1200623_-	hypothetical protein	NA	NA	NA	NA
WP_041228332.1\|1200909_1201353_-	S24 family peptidase	Q6J1N3	Burkholderia_virus	1.4e-20	44.9
WP_013956185.1\|1201729_1201987_+	hypothetical protein	NA	NA	NA	NA
WP_148271561.1\|1202212_1202503_+	hypothetical protein	NA	NA	NA	NA
WP_049800548.1\|1202536_1202749_+	hypothetical protein	NA	NA	NA	NA
WP_013956188.1\|1202745_1203096_+	hypothetical protein	NA	NA	NA	NA
WP_013956189.1\|1203092_1203506_+	hypothetical protein	NA	NA	NA	NA
WP_158310020.1\|1203514_1203688_+	hypothetical protein	NA	NA	NA	NA
WP_013956190.1\|1203687_1204755_+	hypothetical protein	NA	NA	NA	NA
WP_148271610.1\|1204766_1205066_+	hypothetical protein	NA	NA	NA	NA
WP_013956192.1\|1205068_1205455_+	hypothetical protein	NA	NA	NA	NA
WP_148271562.1\|1205652_1206096_+	hypothetical protein	NA	NA	NA	NA
WP_158310021.1\|1206263_1206425_+	hypothetical protein	NA	NA	NA	NA
WP_013956193.1\|1206425_1207016_+	hypothetical protein	A0A0K1Y721	Rhodobacter_phage	3.9e-34	37.2
WP_013956194.1\|1207123_1207642_+\|terminase	terminase small subunit	NA	NA	NA	NA
WP_013956195.1\|1207598_1209647_+\|terminase	phage terminase large subunit family protein	R9TMM4	Vibrio_phage	7.6e-130	41.5
WP_013956196.1\|1209659_1209881_+	hypothetical protein	A0A219Y8X9	Aeromonas_phage	6.9e-05	54.5
WP_013956197.1\|1209882_1211334_+\|portal	phage portal protein	A0A1B2LRR5	Wolbachia_phage	7.9e-81	40.8
WP_013956198.1\|1211398_1213453_+\|head	peptidase U35 phage prohead HK97	B7SYD7	Stenotrophomonas_phage	2.6e-69	31.1
WP_013956199.1\|1213536_1213869_+	DUF2190 family protein	NA	NA	NA	NA
WP_013956200.1\|1213868_1214171_+	hypothetical protein	NA	NA	NA	NA
WP_013956201.1\|1214167_1214743_+	hypothetical protein	NA	NA	NA	NA
WP_013956202.1\|1214763_1214952_+	DUF2635 domain-containing protein	NA	NA	NA	NA
WP_013956203.1\|1214951_1216433_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0C4UQS0	Shigella_phage	2.4e-93	41.1
WP_013956204.1\|1216481_1216847_+\|tail	phage tail tube protein	A0A2P1A4D6	Alteromonadaceae_phage	9.1e-10	34.2
WP_013956205.1\|1216846_1217176_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_013956206.1\|1217255_1218977_+	hypothetical protein	NA	NA	NA	NA
WP_013956207.1\|1219040_1220204_+	DNA circularization N-terminal domain-containing protein	A0A2P9JZK2	Alteromonadaceae_phage	1.7e-33	29.9
WP_013956208.1\|1220200_1221400_+\|plate	baseplate protein	A0A2P9JZK3	Alteromonadaceae_phage	9.9e-37	28.6
WP_041228340.1\|1221420_1221963_+\|plate	phage baseplate assembly protein	Q8SBG6	Shigella_phage	6.9e-38	49.2
WP_013956210.1\|1221962_1222421_+	phage GP46 family protein	A0A2P9JZK5	Alteromonadaceae_phage	3.8e-29	50.4
WP_013956211.1\|1222422_1223475_+\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	1.6e-62	44.9
WP_013956212.1\|1223465_1224131_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_013956213.1\|1224155_1225352_+	hypothetical protein	A0A1D8KLY0	Synechococcus_phage	3.8e-20	29.5
WP_148271611.1\|1225666_1226386_+\|tail	phage tail protein	A9YX14	Burkholderia_phage	4.5e-53	57.6
WP_041227841.1\|1226643_1227501_+	hypothetical protein	NA	NA	NA	NA
WP_013956216.1\|1227588_1228230_+	glycoside hydrolase family 19 protein	F1C5D2	Cronobacter_phage	2.1e-57	56.2
WP_013956217.1\|1228252_1228549_+\|holin	phage holin family protein	C7BGD7	Burkholderia_phage	1.6e-17	51.1
WP_013956218.1\|1228532_1229072_+	DUF2514 family protein	Q3HQV1	Burkholderia_phage	1.3e-09	39.5
WP_013956219.1\|1229091_1229472_-	hypothetical protein	NA	NA	NA	NA
WP_013956220.1\|1229476_1229725_-	hypothetical protein	NA	NA	NA	NA
WP_148271612.1\|1229779_1230364_-	hypothetical protein	A0A291AUV6	Sinorhizobium_phage	5.3e-28	46.0
WP_013956222.1\|1230600_1230783_-	hypothetical protein	NA	NA	NA	NA
WP_148271564.1\|1230843_1231386_-	hypothetical protein	NA	NA	NA	NA
WP_041228342.1\|1231903_1232338_-	universal stress protein	NA	NA	NA	NA
WP_010808971.1\|1232786_1233002_-	YdcH family protein	NA	NA	NA	NA
WP_013956226.1\|1233225_1234044_-	inositol monophosphatase	NA	NA	NA	NA
WP_013956227.1\|1234166_1235066_+	RNA methyltransferase	NA	NA	NA	NA
WP_013956228.1\|1235371_1236115_+	serine O-acetyltransferase	NA	NA	NA	NA
WP_013956229.1\|1236145_1236943_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_013956230.1\|1237009_1237510_-	peptidyl-prolyl cis-trans isomerase	A0A076FI46	Aureococcus_anophage	8.6e-11	34.0
WP_013956231.1\|1237531_1238116_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_013956232.1\|1238187_1238889_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_013956233.1\|1239172_1240561_+\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	2.0e-41	33.2
WP_013956234.1\|1240557_1241397_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_010808961.1\|1241512_1242484_+	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_013956235.1\|1242581_1243901_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_010808959.1\|1244024_1245275_+	aspartate kinase	NA	NA	NA	NA
WP_148271565.1\|1246011_1249386_+	EAL domain-containing protein	NA	NA	NA	NA
WP_148271613.1\|1249481_1250105_+	hypothetical protein	NA	NA	NA	NA
WP_013956238.1\|1250352_1250532_-	hypothetical protein	NA	NA	NA	NA
WP_013956239.1\|1250732_1254236_+	pyruvate carboxylase	NA	NA	NA	NA
WP_013956240.1\|1254321_1254672_-	hypothetical protein	NA	NA	NA	NA
WP_041228345.1\|1256794_1258096_-	MFS transporter	Q6JIH2	Burkholderia_virus	2.1e-56	34.3
WP_013956243.1\|1258247_1259228_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_013956244.1\|1259298_1262865_-	indolepyruvate ferredoxin oxidoreductase family protein	NA	NA	NA	NA
WP_013956245.1\|1262956_1263991_-	Ldh family oxidoreductase	NA	NA	NA	NA
WP_013956246.1\|1263987_1264692_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_013956247.1\|1264698_1265853_-	UxaA family hydrolase	NA	NA	NA	NA
WP_013956248.1\|1265858_1266149_-	UxaA family hydrolase	NA	NA	NA	NA
WP_013956249.1\|1266366_1266828_+	hypothetical protein	NA	NA	NA	NA
WP_013956250.1\|1266817_1267183_+	hypothetical protein	NA	NA	NA	NA
WP_013956251.1\|1267235_1268207_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_013956252.1\|1268240_1269035_+	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_013956253.1\|1269151_1270270_+	Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha	NA	NA	NA	NA
WP_013956254.1\|1270292_1270643_+	NAD(P) transhydrogenase subunit alpha	NA	NA	NA	NA
WP_013956255.1\|1270639_1272109_+	NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta	NA	NA	NA	NA
WP_041228346.1\|1272161_1273211_-\|transposase	transposase	Q19ZT4	Mycobacterium_virus	1.1e-39	43.3

DBSCAN-SWA_4

1361981 : 1371346

Burkholderia_virus(42.86%)

integrase

attL 1354936:1354950|attR 1368973:1368987

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1354936:1354950	attL	NA	NA	NA	NA
WP_013956330.1\|1361981_1362392_+	integration host factor subunit alpha	A0A1P8CWT5	Bacillus_phage	2.9e-12	40.0
WP_013956331.1\|1362508_1362934_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_013956332.1\|1363194_1364499_+	hypothetical protein	NA	NA	NA	NA
WP_013956333.1\|1364500_1365619_-\|integrase	tyrosine-type recombinase/integrase	Q6JIJ8	Burkholderia_virus	3.2e-82	46.2
WP_085959680.1\|1365615_1365855_-	DUF4224 domain-containing protein	Q6JIJ7	Burkholderia_virus	2.0e-10	51.5
WP_013956335.1\|1365908_1366433_-	DUF1643 domain-containing protein	A0A0U1W068	Pseudomonas_phage	2.5e-21	42.7
WP_148271566.1\|1366443_1366887_-	hypothetical protein	NA	NA	NA	NA
WP_013956337.1\|1366883_1367516_-	hypothetical protein	Q5QF30	Pseudomonas_virus	1.6e-38	42.9
WP_148271567.1\|1367560_1367800_+	hypothetical protein	NA	NA	NA	NA
WP_013956339.1\|1367802_1368867_-	site-specific DNA-methyltransferase	Q8W6P4	Burkholderia_virus	3.6e-115	57.8
WP_041227854.1\|1368902_1369538_+	hypothetical protein	NA	NA	NA	NA
1368973:1368987	attR	NA	NA	NA	NA
WP_013956341.1\|1369555_1371346_-	DNA cytosine methyltransferase	L7TH64	Pseudomonas_virus	7.8e-187	62.7

DBSCAN-SWA_5

3127944 : 3137259

Methanothermobacter_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013957881.1\|3127944_3129147_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	9.9e-37	30.6
WP_011615967.1\|3129218_3129719_+	dUTP diphosphatase	A0A289ZTC1	Serratia_phage	1.8e-40	54.2
WP_013957882.1\|3129773_3130622_-	VOC family protein	NA	NA	NA	NA
WP_041228104.1\|3130664_3131672_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_013957884.1\|3131847_3134142_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	3.1e-172	43.2
WP_010814998.1\|3134138_3134465_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.3e-12	46.9
WP_010814999.1\|3134977_3135184_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.9e-20	75.8
WP_013957885.1\|3135397_3135859_-	VOC family protein	NA	NA	NA	NA
WP_013957886.1\|3136008_3137259_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	8.8e-12	64.8

DBSCAN-SWA_6

3665661 : 3671722

uncultured_Caudovirales_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013958328.1\|3665661_3666249_-	phosphoheptose isomerase	A0A067XQR2	Caulobacter_phage	1.4e-15	32.0
WP_013958330.1\|3666725_3667634_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.8e-35	40.8
WP_013958331.1\|3667721_3668489_-	septal ring lytic transglycosylase RlpA family protein	H2BCY4	Synechococcus_phage	1.3e-18	53.2
WP_013958332.1\|3668770_3669421_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_013958333.1\|3669425_3670082_+	exonuclease	A0A2L0UZL4	Agrobacterium_phage	3.9e-35	40.4
WP_010812133.1\|3670289_3670517_+	hypothetical protein	NA	NA	NA	NA
WP_013958334.1\|3670600_3670966_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	2.4e-18	44.4
WP_013958335.1\|3671140_3671722_+	N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	1.8e-20	41.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_015727

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

291536 : 342405

uncultured_virus(22.22%)

integrase,transposase

attL 305513:305540|attR 325204:325231

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080569627.1\|291536_292010_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_041228990.1\|292352_297860_+	AAA family ATPase	Q67624	IC4_retrovirus	1.3e-06	27.2
WP_013958777.1\|299759_300440_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_013958778.1\|300571_301654_+	alkene reductase	NA	NA	NA	NA
WP_013958779.1\|301707_302496_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_041229179.1\|302617_303487_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_013958781.1\|303492_304494_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
305513:305540	attL	NA	NA	NA	NA
WP_080569628.1\|305831_306107_+	hypothetical protein	NA	NA	NA	NA
WP_148271735.1\|306057_307311_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.8e-42	42.0
WP_013958784.1\|307409_307658_+	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_049800699.1\|307740_308265_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_013958786.1\|308569_309652_-	maleylacetate reductase	NA	NA	NA	NA
WP_013958788.1\|309664_310669_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_041228993.1\|310829_311768_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_148271736.1\|312985_313462_+	hypothetical protein	NA	NA	NA	NA
WP_013958792.1\|313563_314523_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	4.2e-62	44.1
WP_148271737.1\|314616_315162_+	hypothetical protein	NA	NA	NA	NA
WP_158310033.1\|315158_315425_+	hypothetical protein	NA	NA	NA	NA
WP_080569629.1\|315471_316071_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_013958796.1\|316067_317801_+	carbamoyltransferase	A0A1D8KNV1	Synechococcus_phage	1.8e-31	30.1
WP_013958797.1\|317775_318642_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_013958798.1\|318673_319381_+	NUDIX hydrolase	NA	NA	NA	NA
WP_013958800.1\|320742_321897_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_013958801.1\|322227_322611_-	type II toxin-antitoxin system death-on-curing family toxin	D0R0D2	Streptococcus_phage	5.6e-10	41.7
WP_013958802.1\|322617_322848_-	hypothetical protein	NA	NA	NA	NA
WP_013958803.1\|323025_324327_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013958804.1\|324428_324806_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_013958805.1\|324805_325042_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_013958806.1\|325274_326453_-	DUF1016 family protein	A0A0U2BZN7	Salmonella_phage	1.6e-63	76.2
325204:325231	attR	NA	NA	NA	NA
WP_013958809.1\|327861_329625_-	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_041228994.1\|329801_331352_+	methylmalonyl-CoA carboxyltransferase	NA	NA	NA	NA
WP_041228995.1\|331407_334725_+	carbamoyl phosphate synthase large subunit	NA	NA	NA	NA
WP_013958812.1\|334768_337240_+	CoA transferase	NA	NA	NA	NA
WP_013958813.1\|337283_338312_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_013958814.1\|338499_338850_-	DNA-binding protein	A0A222YXG1	Escherichia_phage	9.9e-30	54.7
WP_013958815.1\|338849_339152_-	type II toxin-antitoxin system HigB family toxin	A0A0P0ZE17	Stx2-converting_phage	4.9e-09	40.6
WP_013958816.1\|339370_339670_-	hypothetical protein	NA	NA	NA	NA
WP_013952233.1\|341145_342405_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.7e-39	44.1

DBSCAN-SWA_2

641603 : 733417

uncultured_virus(21.43%)

integrase,transposase

attL 641365:641381|attR 660178:660194

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
641365:641381	attL	NA	NA	NA	NA
WP_013959084.1\|641603_643235_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q7ZJT6	Amphotropic_murine_leukemia_virus	1.6e-05	26.7
WP_013959085.1\|643241_644111_+	TniB family NTP-binding protein	NA	NA	NA	NA
WP_013958800.1\|644740_645895_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_041229029.1\|646735_647461_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_013959088.1\|647571_648552_+	nitrilase	NA	NA	NA	NA
WP_041229030.1\|648553_649489_+	threonine/serine dehydratase	NA	NA	NA	NA
WP_041229031.1\|650246_651140_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	1.1e-05	28.9
WP_013959092.1\|651294_652911_+	MFS transporter	Q6JIH2	Burkholderia_virus	3.4e-40	32.0
WP_013959093.1\|652943_653870_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_099047508.1\|654283_655419_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	4.2e-13	26.5
WP_013959098.1\|657550_659404_-	cation acetate symporter	NA	NA	NA	NA
WP_041229032.1\|659413_659764_-	DUF485 domain-containing protein	NA	NA	NA	NA
WP_013959100.1\|660023_660947_+	LysR family transcriptional regulator	NA	NA	NA	NA
660178:660194	attR	NA	NA	NA	NA
WP_148271755.1\|661097_662351_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.8e-41	41.5
WP_013959102.1\|662755_663649_-	SDR family oxidoreductase	M1HZA6	Acanthocystis_turfacea_Chlorella_virus	1.0e-09	23.5
WP_013959103.1\|663753_664587_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_041229245.1\|664780_665470_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_041229033.1\|665569_666277_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_013959106.1\|666411_667422_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_013959107.1\|667523_670946_-	adenylate/guanylate cyclase domain-containing protein	NA	NA	NA	NA
WP_013959108.1\|671106_672450_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_013959109.1\|672632_673343_+	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_013959110.1\|673356_674526_+	M20 family metallopeptidase	NA	NA	NA	NA
WP_158310038.1\|674527_674863_+	DUF485 domain-containing protein	NA	NA	NA	NA
WP_148271811.1\|674904_676773_+	cation acetate symporter	NA	NA	NA	NA
WP_148271756.1\|677148_678501_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_013959115.1\|678936_679401_-	hypothetical protein	NA	NA	NA	NA
WP_013959116.1\|679435_679792_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_049800717.1\|680121_680505_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_041229250.1\|680536_680782_-	plasmid stabilization protein	NA	NA	NA	NA
WP_013959119.1\|680973_682206_+	DNA-binding protein	NA	NA	NA	NA
WP_041229034.1\|682189_682462_+	H-NS histone family protein	NA	NA	NA	NA
WP_041229036.1\|682730_683846_+	H-NS histone family protein	NA	NA	NA	NA
WP_013959122.1\|683921_685181_+	RES domain-containing protein	NA	NA	NA	NA
WP_148271757.1\|685927_686428_+	hypothetical protein	NA	NA	NA	NA
WP_013952233.1\|686387_687647_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.7e-39	44.1
WP_148271758.1\|690078_690678_+	hypothetical protein	Q8LTB7	Lactobacillus_phage	2.7e-11	37.4
WP_013959128.1\|691269_692061_-	hypothetical protein	NA	NA	NA	NA
WP_013959129.1\|692087_693929_-	hypothetical protein	NA	NA	NA	NA
WP_013959130.1\|694102_694840_-	hypothetical protein	NA	NA	NA	NA
WP_013959132.1\|696869_697574_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_041229041.1\|699856_700891_+	H-NS histone family protein	NA	NA	NA	NA
WP_013959138.1\|701312_702044_+	hypothetical protein	NA	NA	NA	NA
WP_148271759.1\|702411_703008_+	hypothetical protein	NA	NA	NA	NA
WP_041229042.1\|704142_704982_+	hypothetical protein	NA	NA	NA	NA
WP_080569683.1\|705757_706072_+	H-NS histone family protein	NA	NA	NA	NA
WP_013959144.1\|706147_706906_+	tol-pal system protein YbgF	NA	NA	NA	NA
WP_158310039.1\|708764_709505_-	FRG domain-containing protein	A0A1S6KZX9	Salmonella_phage	7.3e-06	31.0
WP_013959146.1\|709510_710065_-	YfbU family protein	NA	NA	NA	NA
WP_080569639.1\|711112_711511_-	HNH endonuclease	NA	NA	NA	NA
WP_148271760.1\|713184_716349_+	hypothetical protein	Q858S3	Enterobacteria_phage	1.1e-13	39.6
WP_148271761.1\|717960_719250_+	hypothetical protein	NA	NA	NA	NA
WP_148271762.1\|720061_722224_+	endonuclease	NA	NA	NA	NA
WP_013959154.1\|722869_723595_-	hypothetical protein	NA	NA	NA	NA
WP_158310040.1\|723756_724308_-	hypothetical protein	NA	NA	NA	NA
WP_013959157.1\|725365_726121_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	7.9e-08	24.6
WP_013959158.1\|726253_727735_+	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	2.9e-22	26.6
WP_013959160.1\|729375_730887_-	ATP-binding protein	NA	NA	NA	NA
WP_049800720.1\|731273_731780_+	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	3.1e-08	29.6
WP_148271735.1\|732163_733417_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.8e-42	42.0

DBSCAN-SWA_3

740618 : 786470

Acidithiobacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158310041.1\|740618_740789_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_013959172.1\|744898_745189_+	hypothetical protein	NA	NA	NA	NA
WP_013959173.1\|745721_745922_+	hypothetical protein	NA	NA	NA	NA
WP_013959174.1\|746580_747264_+	hypothetical protein	NA	NA	NA	NA
WP_041229260.1\|747872_748994_+	hypothetical protein	NA	NA	NA	NA
WP_013958589.1\|750118_750415_+\|transposase	IS3 family transposase	A9YX41	Burkholderia_phage	1.3e-11	40.4
WP_013959177.1\|750411_750999_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.7e-27	39.3
WP_017510466.1\|751042_752296_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	7.4e-43	42.0
WP_041229049.1\|753069_753330_+	hypothetical protein	NA	NA	NA	NA
WP_041229262.1\|753410_755018_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	1.2e-66	35.4
WP_013954297.1\|755073_755427_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_013954296.1\|755407_755896_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_013959180.1\|756442_756694_+	hypothetical protein	NA	NA	NA	NA
WP_158310042.1\|757729_757900_+	hypothetical protein	NA	NA	NA	NA
WP_013959184.1\|757920_758361_+	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_013959185.1\|758388_759672_-	MFS transporter	NA	NA	NA	NA
WP_013959187.1\|760158_761580_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_013959188.1\|761626_762538_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_148271765.1\|762673_763465_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_013959190.1\|763450_763867_-	hypothetical protein	NA	NA	NA	NA
WP_013959191.1\|764026_764308_-	hypothetical protein	NA	NA	NA	NA
WP_013959193.1\|765589_766024_+	CopG family transcriptional regulator	NA	NA	NA	NA
WP_013959194.1\|766077_767268_+	PHB depolymerase family esterase	NA	NA	NA	NA
WP_085959710.1\|768067_768649_+\|transposase	transposase	NA	NA	NA	NA
WP_063712361.1\|769112_769763_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_148271766.1\|769842_770544_-	helix-turn-helix transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	2.1e-07	40.5
WP_013959201.1\|770689_772030_-	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	1.5e-49	32.9
WP_013959202.1\|772290_772707_+	cupin domain-containing protein	NA	NA	NA	NA
WP_041229052.1\|772769_773090_+	ferredoxin family protein	NA	NA	NA	NA
WP_012354456.1\|773931_774393_+	excisionase family DNA-binding protein	K4ICM4	Acidithiobacillus_phage	9.9e-54	74.7
WP_013959204.1\|774395_774968_+	PIN domain-containing protein	K4HZX4	Acidithiobacillus_phage	6.7e-68	65.3
WP_013959205.1\|775312_775681_+	calcium-binding protein	NA	NA	NA	NA
WP_013959206.1\|775912_777691_+	hypothetical protein	NA	NA	NA	NA
WP_041229053.1\|778067_779498_+	hypothetical protein	NA	NA	NA	NA
WP_041229054.1\|779490_780177_+	DUF4194 domain-containing protein	NA	NA	NA	NA
WP_013959209.1\|780166_783838_+	hypothetical protein	NA	NA	NA	NA
WP_041229055.1\|784928_786470_+\|transposase	IS21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

1413924 : 1438841

Wolbachia_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_035827570.1\|1413924_1414221_-\|transposase	transposase	NA	NA	NA	NA
WP_013959773.1\|1414469_1414685_-	hypothetical protein	NA	NA	NA	NA
WP_013959774.1\|1414753_1415011_-	hypothetical protein	NA	NA	NA	NA
WP_013959775.1\|1415029_1416325_-	hypothetical protein	NA	NA	NA	NA
WP_041229359.1\|1416427_1417750_-	hypothetical protein	NA	NA	NA	NA
WP_013959777.1\|1418008_1418653_-	response regulator transcription factor	NA	NA	NA	NA
WP_013959778.1\|1418655_1419513_-	sensor histidine kinase	NA	NA	NA	NA
WP_013959779.1\|1419681_1420140_-	response regulator transcription factor	NA	NA	NA	NA
WP_013959780.1\|1420057_1420249_-	response regulator transcription factor	NA	NA	NA	NA
WP_013959781.1\|1420815_1422237_+\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	5.4e-82	37.0
WP_013959782.1\|1422276_1423242_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	2.7e-08	30.0
WP_080569694.1\|1424035_1424245_+	hypothetical protein	NA	NA	NA	NA
WP_148271790.1\|1424561_1425344_+	phytanoyl-CoA dioxygenase family protein	NA	NA	NA	NA
WP_013959784.1\|1425349_1426579_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_041228685.1\|1426592_1427645_-\|transposase	transposase	A0A0R8V9X2	Thermobifida_phage	2.1e-30	35.7
WP_013959785.1\|1427734_1428577_+	hypothetical protein	NA	NA	NA	NA
WP_148271791.1\|1428748_1430002_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	9.7e-43	42.0
WP_013959787.1\|1430470_1431745_-	thioredoxin family protein	NA	NA	NA	NA
WP_148271792.1\|1431838_1432087_+	hypothetical protein	NA	NA	NA	NA
WP_013959788.1\|1435061_1435637_-	S26 family signal peptidase	NA	NA	NA	NA
WP_013959789.1\|1435633_1436167_-	DUF2840 domain-containing protein	NA	NA	NA	NA
WP_013959790.1\|1436235_1437657_+\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	1.7e-83	37.7
WP_013953603.1\|1437818_1438841_+\|transposase	IS110 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_015723

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015723_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015723_1

2683665-2683810

Orphan

Consensus_repeat	Method
CGCAGAAACAGGTACGCTTCGCC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_015723_1

>merge|NC_015723|1|2683665-2683810|CRISPRCasFinder
CGCAGAAACAGGTACGCCGGCGGGAGCAGGGCACAACGTCATGGCACGCAGAAACGGGTACGCCCCCAAAGATGCGAGGCGGATGGCCACCAGGTCGCGCCGCGGCAACCATGGCATGTCTGCGCAGAAACGGGTACGGCACGCAC

>NC_015723|1|1|2683665-2683810|CRISPRCasFinder
CGCAGAAACAGGTACGCCGGCGG	GAGCAGGGCACAACGTCATGGCA
CGCAGAAACGGGTACGCCCCCAA	AGATGCGAGGCGGATGGCCACCAGGTCGCGCCGCGGCAACCATGGCATGTCTG
CGCAGAAACGGGTACGGCACGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015723.1\|WP_013954096.1\|2676435_2676825_+\|hypothetical-protein	unknown	unknown	unknown
NC_015723.1\|WP_013954101.1\|2681775_2683092_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|379017
NC_015723.1\|WP_013954098.1\|2678448_2678919_-\|hypothetical-protein	unknown	unknown	unknown
NC_015723.1\|WP_189374659.1\|2679631_2680927_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NC_015723.1\|WP_013954093.1\|2672531_2674133_-\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NC_015723.1\|WP_041228759.1\|2670277_2672446_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227113
NC_015723.1\|WP_013954094.1\|2674306_2675380_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NC_015723.1\|WP_010811149.1\|2681427_2681631_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_015723.1\|WP_013954097.1\|2676955_2678323_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_015723.1\|WP_041228761.1\|2676086_2676290_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015723.1\|WP_041228759.1\|2670277_2672446_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227113	COG4772, FecA, Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism].	0
NC_015723.1\|WP_013954101.1\|2681775_2683092_+\|IS4-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	4.68017e-28
NC_015723.1\|WP_189374659.1\|2679631_2680927_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.53129e-169
NC_015723.1\|WP_013954094.1\|2674306_2675380_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	8.15106e-50
NC_015723.1\|WP_013954093.1\|2672531_2674133_-\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NC_015723.1\|WP_010811149.1\|2681427_2681631_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.31341e-34
NC_015723.1\|WP_013954097.1\|2676955_2678323_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.01011e-145

>NC_015723.1|WP_013954101.1|2681775_2683092_+|IS4-family-transposase
MLSEQVHTALELSEPASFARLSEHLPMAWIEHALAATGTASVRRRRLPAEQVVWLVIALALYRHQSIPDVLETLDLALPNDASACVSKSGIAQARERLGDKPLLWLFEQTARAWVAQDAAHYKWKGLALYAMDGTTFRTADSPENRLHFGAQSYASGKVASYPQVRGVSLTAVPTHLVADIAFGRYGCNEMLYAKPLIERIPDDSLTIFDKGFLAAEILWGLRMGGSERHFLIPAKKNLQWELLSGSADDGIVQMKVSPQARRKNPALPETWTARAIRDEESERVLLTSLTDRRRFKAADILACYRRRWEIETSYRELKQTMLGAELTLRSRQPEGVHQEIWGALIAYNLVRLEMAKAALEARVEPTDLSFVLALRLIQGELTWAAGMAPGKLPAHLQRMRAKLQLAIVQKRRGRKCPRVVKALPKRYTVRFLRKDLN
>NC_015723.1|WP_010811149.1|2681427_2681631_+|cold-shock-protein
MQTGIVKWFNDAKGFGFIKPDAGGDDLFAHFSEIRADGFKSLQENQRVQFEVKNGPKGLQAANITPL
>NC_015723.1|WP_189374659.1|2679631_2680927_-|NCS2-family-permease
MIERLFRLREHQTDVRTEILAGVTTFLTMAYIIFVNPSILGDAGMPKDAVFVATCLAAAIGTLIMGFYANYPIAMAPGMGLNAYFAYTVVKGMGFAWEAALGAVFISGCLFLLVTLFRVREMIVNGIPHSIRVAITAGIGLFLAIVALKNAGIVTASPATLVTIGDLHQPSAVLAIIGFFVIVALDHLRVKGAILIGILLTTLLSFAFAGNTFHGVFSAPPSLSPTLFKLDISAALSIGIINVVLVFFLVELFDATGTLMGVANRAGLLKAGKMDRLNKALMSDSTAIMAGSFLGTSSTTAYIESASGVQAGGRTGLTAVTVAVLFLAALFIAPLAGTVPAYATAPALLYVSCLMLRELLEVDWNDVTEVVPAVMTALGMPFTYSVANGVAFGFISYAALKLLTGRARSVPVMVWIIAAVFIFKFYYLPGH
>NC_015723.1|WP_013954098.1|2678448_2678919_-|hypothetical-protein
MTAGEIRRPAIGPVRETNNRSIRSIHHAWAAVGEAAGEAPSKRAVQEGATADVAALLAEDSELSDSARAAVANLLRRHRLLEGELARQRTLLQEWILSQLTYKTLYYQYSGQSPQAPRLELMREKETVRRRIRDQLQAGADYLAAPDEQLRSLSSS
>NC_015723.1|WP_013954097.1|2676955_2678323_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MDRLCKASRTAQIVVVSRHEDFGFDPSGSATGWEIRRVQQIRDLERVVRACPPMAGVIDLQSDYSDAEFAQLEQALQYLHITWVAITSDEMLAQERVRRLIRDYCVDYVRMPFSMPELLYTLKHAQGMASLHGVRPQETASRGTMIGECAAMRAMFRSLAKVAHNEAPVFISGESGTGKELAAQAIHDASSRRKGPFIAINCGAIPSHLVQSELFGYEKGAFTGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGMITRLGGHQSIPLNLRIISATHVDLVAAQADGRFRSDLFHRLCVLTLTIPALRERGEDILQLANAVLTEHGHEAHRRIRGFSACATQAMMQYAWPGNVRELINRVRRAIVMTDNRKITAEDLQLHGGAELPRKTLDAIREEAEREAIRTVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVESQPTAGE
>NC_015723.1|WP_013954096.1|2676435_2676825_+|hypothetical-protein
MTAGMLAATVLAVFSSSAAAASYAWFDRPEAASANSHAAVSNDVYVRGFGWAWGELQLSPDTSSGAAMPTPGRQARDKPERGAIVPWRQQDENGPPRHPRGKLSMNLAAEPMDAASGGSGASQPRAVVR
>NC_015723.1|WP_041228761.1|2676086_2676290_+|hypothetical-protein
MTARRRSYRLAGPPPSVVDLLSSPLLPHPRARTPPAAPAAQGAGCAATARQGVARTAFRRHAGKRRA
>NC_015723.1|WP_013954094.1|2674306_2675380_-|YihY/virulence-factor-BrkB-family-protein
MRSMMNARALAAQTVTRRHAQRTRDPPGASRQHQAVTDNTERPSTSAGNAAPQPRRRRPHWLPDRHTGTRTLRVVAAAINSWFAHRAASKGAALSFYMLFSLAPILVLVISIAGLFFGAEAARGEIFSQLEGLVGEQGAAAIQEILAATHRAGGSGMAALVATAILFVGATSAFAELKSSLDDIWHVPVPATAGWQQLLRARLLSFSLVLVLAFMLLVSLIVNAALAVVERLWGQLWTQSWFAPVADVISTAFSFAVVTALFAVIFKMLPNARIAWRDVTMGAVITALLFSVGKRLIGLYLGNSAVASSYGAAGSVVALMLWVYYSAQIFFFGAELTRQYALQFGSLRGKPADKLAE
>NC_015723.1|WP_013954093.1|2672531_2674133_-|peptide-chain-release-factor-3
MSSLVSEIARRRTFAIISHPDAGKTTLTEKLLWFGGAIQVAGEVRARKADRHATSDWMELEKQRGISVTSSVMQFPYRRETANGKAQENIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSVNGVEAQTIKLLNVCRLRDTPILTFINKLDREGRSPIELLDEIEEVLQIQCAPMTWPIGMGKAFRGVYHLIDDKVQLFDPHGEKGTAAILDGLDNPELDRILGSQAEELRIEIELVRGASHTFDKDAFLNGKQTPVYFGSAINNFGVQSLLDALCELSPPPLARNTDSRVVEPQEPKFTGFVFKIQANMDPRHRDRIAFVRVCSGRFERGMKLLHVSAGKTVAINNAITFMAQDRNTTEEAYAGDIIGVPNHGTIRLGDVFTEGEPLKFTGIPSFAPEFFRRARLNNPLKVKQLQKGLQQLAEEGATQMFRPLASNDLVLGAVGILQFDVVAHRLEHEYGVDAIFESHECATARWLKGTPAEIEKLIAKAGHNVALDGAGDHVYLAPSMVNLRLTQERFPELQFLETREIV
>NC_015723.1|WP_041228759.1|2670277_2672446_+|TonB-dependent-siderophore-receptor
MQPAFRLSGGAIGAALLFAQLAALPAHAADPAPVSAPAANPEATLNTVTVVGNWLENANEAKVLEHPGARTIVDRETFQEAGANNVREVLRRIPGVQVQENNGTGGSDVSLNVGVRGLTSRLSPRSTILMDGVPLAVAPYGQPQLSMAPLSLGNLETIDVVRGAGSVRYGPQNVGGIINFVTRPVPKLFAADASVSTDIYSHGGSVKTNPTAFIGGTNDNGLGGALLYSGIHGNGYRESNDHVNIDDLMLKGAYRISKTDELSAAFHYYEGRAGMPGGLTSAQYAADPFQSVRPYDNFDGRRSDFSLKYSHNDNNRKFEVLTYYTDSFRGSNIEQQGTGAQANLRRLTAAPRNYHTFAIEPRYSQLFRGESMSHEVSVGYRFLREASDEKASRTLFYTPGTVDPTTLPSPVYQSRTGGTTANAVYLDDTINVGSWTITPGLRYEFIRSYVTDNFSGARNDVSSNEPLPSLAVMYHVSDQWKLFANAGVSFGPLQYFQIAQTTNGLTPEKAKTYEVGTHFNANGWGGELTLFNIDFDDELQLRGGTGGAPDAWTNLGATTHRGVESSLRYDFGALDKSLAGLSAYATYTFTEATYNQGNFAGRDLPFYSRHVATVGMRYARNRWALNVDGFAQSKQHSPGDPSTSTSYQTAESANGALGDIPGYALLNMRLGYDFGKSAQNLKVAVGVKNVFDKRYFTRSTDNNAGKYVGMPRTFYIQASLAY

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Crispr_ID: NC_015723_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015723_2

2683921-2684101

Orphan

Consensus_repeat	Method
CGCAGAAACAGGTACGCTTCGCC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_015723_2

>merge|NC_015723|2|2683921-2684101|CRISPRCasFinder
CGCAGAAACGGGTACGCTGGGCCGAGGAAGTCCGGTGGCAGGCACGCAGAAACAGGTACGCTTCGCCGCGCACAAGACTCCCGGGGCGGGACGCAGAAATGGGTACGCCGCAGAAACAGGTACGCTGCGCCAGCACGGCAGTCGCTTTTCAGGCCAGCGCAGAAACAGGTACGGTTTCAGG

>NC_015723|2|2|2683921-2684101|CRISPRCasFinder
CGCAGAAACGGGTACGCTGGGCC	GAGGAAGTCCGGTGGCAGGCA
CGCAGAAACAGGTACGCTTCGCC	GCGCACAAGACTCCCGGGGCGGGA
CGCAGAAATGGGTACGCCGCAGA	AACAGGTACGCTGCGCCAGCACGGCAGTCGCTTTTCAGGCCAG
CGCAGAAACAGGTACGGTTTCAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015723.1\|WP_013954096.1\|2676435_2676825_+\|hypothetical-protein	unknown	unknown	unknown
NC_015723.1\|WP_013954101.1\|2681775_2683092_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|379017
NC_015723.1\|WP_013954098.1\|2678448_2678919_-\|hypothetical-protein	unknown	unknown	unknown
NC_015723.1\|WP_189374659.1\|2679631_2680927_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NC_015723.1\|WP_013954093.1\|2672531_2674133_-\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NC_015723.1\|WP_041228759.1\|2670277_2672446_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227113
NC_015723.1\|WP_013954094.1\|2674306_2675380_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NC_015723.1\|WP_010811149.1\|2681427_2681631_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_015723.1\|WP_013954097.1\|2676955_2678323_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_015723.1\|WP_041228761.1\|2676086_2676290_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015723.1\|WP_041228759.1\|2670277_2672446_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227113	COG4772, FecA, Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism].	0
NC_015723.1\|WP_013954101.1\|2681775_2683092_+\|IS4-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	4.68017e-28
NC_015723.1\|WP_189374659.1\|2679631_2680927_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.53129e-169
NC_015723.1\|WP_013954094.1\|2674306_2675380_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	8.15106e-50
NC_015723.1\|WP_013954093.1\|2672531_2674133_-\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NC_015723.1\|WP_010811149.1\|2681427_2681631_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.31341e-34
NC_015723.1\|WP_013954097.1\|2676955_2678323_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.01011e-145

>NC_015723.1|WP_013954101.1|2681775_2683092_+|IS4-family-transposase
MLSEQVHTALELSEPASFARLSEHLPMAWIEHALAATGTASVRRRRLPAEQVVWLVIALALYRHQSIPDVLETLDLALPNDASACVSKSGIAQARERLGDKPLLWLFEQTARAWVAQDAAHYKWKGLALYAMDGTTFRTADSPENRLHFGAQSYASGKVASYPQVRGVSLTAVPTHLVADIAFGRYGCNEMLYAKPLIERIPDDSLTIFDKGFLAAEILWGLRMGGSERHFLIPAKKNLQWELLSGSADDGIVQMKVSPQARRKNPALPETWTARAIRDEESERVLLTSLTDRRRFKAADILACYRRRWEIETSYRELKQTMLGAELTLRSRQPEGVHQEIWGALIAYNLVRLEMAKAALEARVEPTDLSFVLALRLIQGELTWAAGMAPGKLPAHLQRMRAKLQLAIVQKRRGRKCPRVVKALPKRYTVRFLRKDLN
>NC_015723.1|WP_010811149.1|2681427_2681631_+|cold-shock-protein
MQTGIVKWFNDAKGFGFIKPDAGGDDLFAHFSEIRADGFKSLQENQRVQFEVKNGPKGLQAANITPL
>NC_015723.1|WP_189374659.1|2679631_2680927_-|NCS2-family-permease
MIERLFRLREHQTDVRTEILAGVTTFLTMAYIIFVNPSILGDAGMPKDAVFVATCLAAAIGTLIMGFYANYPIAMAPGMGLNAYFAYTVVKGMGFAWEAALGAVFISGCLFLLVTLFRVREMIVNGIPHSIRVAITAGIGLFLAIVALKNAGIVTASPATLVTIGDLHQPSAVLAIIGFFVIVALDHLRVKGAILIGILLTTLLSFAFAGNTFHGVFSAPPSLSPTLFKLDISAALSIGIINVVLVFFLVELFDATGTLMGVANRAGLLKAGKMDRLNKALMSDSTAIMAGSFLGTSSTTAYIESASGVQAGGRTGLTAVTVAVLFLAALFIAPLAGTVPAYATAPALLYVSCLMLRELLEVDWNDVTEVVPAVMTALGMPFTYSVANGVAFGFISYAALKLLTGRARSVPVMVWIIAAVFIFKFYYLPGH
>NC_015723.1|WP_013954098.1|2678448_2678919_-|hypothetical-protein
MTAGEIRRPAIGPVRETNNRSIRSIHHAWAAVGEAAGEAPSKRAVQEGATADVAALLAEDSELSDSARAAVANLLRRHRLLEGELARQRTLLQEWILSQLTYKTLYYQYSGQSPQAPRLELMREKETVRRRIRDQLQAGADYLAAPDEQLRSLSSS
>NC_015723.1|WP_013954097.1|2676955_2678323_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MDRLCKASRTAQIVVVSRHEDFGFDPSGSATGWEIRRVQQIRDLERVVRACPPMAGVIDLQSDYSDAEFAQLEQALQYLHITWVAITSDEMLAQERVRRLIRDYCVDYVRMPFSMPELLYTLKHAQGMASLHGVRPQETASRGTMIGECAAMRAMFRSLAKVAHNEAPVFISGESGTGKELAAQAIHDASSRRKGPFIAINCGAIPSHLVQSELFGYEKGAFTGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGMITRLGGHQSIPLNLRIISATHVDLVAAQADGRFRSDLFHRLCVLTLTIPALRERGEDILQLANAVLTEHGHEAHRRIRGFSACATQAMMQYAWPGNVRELINRVRRAIVMTDNRKITAEDLQLHGGAELPRKTLDAIREEAEREAIRTVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVESQPTAGE
>NC_015723.1|WP_013954096.1|2676435_2676825_+|hypothetical-protein
MTAGMLAATVLAVFSSSAAAASYAWFDRPEAASANSHAAVSNDVYVRGFGWAWGELQLSPDTSSGAAMPTPGRQARDKPERGAIVPWRQQDENGPPRHPRGKLSMNLAAEPMDAASGGSGASQPRAVVR
>NC_015723.1|WP_041228761.1|2676086_2676290_+|hypothetical-protein
MTARRRSYRLAGPPPSVVDLLSSPLLPHPRARTPPAAPAAQGAGCAATARQGVARTAFRRHAGKRRA
>NC_015723.1|WP_013954094.1|2674306_2675380_-|YihY/virulence-factor-BrkB-family-protein
MRSMMNARALAAQTVTRRHAQRTRDPPGASRQHQAVTDNTERPSTSAGNAAPQPRRRRPHWLPDRHTGTRTLRVVAAAINSWFAHRAASKGAALSFYMLFSLAPILVLVISIAGLFFGAEAARGEIFSQLEGLVGEQGAAAIQEILAATHRAGGSGMAALVATAILFVGATSAFAELKSSLDDIWHVPVPATAGWQQLLRARLLSFSLVLVLAFMLLVSLIVNAALAVVERLWGQLWTQSWFAPVADVISTAFSFAVVTALFAVIFKMLPNARIAWRDVTMGAVITALLFSVGKRLIGLYLGNSAVASSYGAAGSVVALMLWVYYSAQIFFFGAELTRQYALQFGSLRGKPADKLAE
>NC_015723.1|WP_013954093.1|2672531_2674133_-|peptide-chain-release-factor-3
MSSLVSEIARRRTFAIISHPDAGKTTLTEKLLWFGGAIQVAGEVRARKADRHATSDWMELEKQRGISVTSSVMQFPYRRETANGKAQENIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSVNGVEAQTIKLLNVCRLRDTPILTFINKLDREGRSPIELLDEIEEVLQIQCAPMTWPIGMGKAFRGVYHLIDDKVQLFDPHGEKGTAAILDGLDNPELDRILGSQAEELRIEIELVRGASHTFDKDAFLNGKQTPVYFGSAINNFGVQSLLDALCELSPPPLARNTDSRVVEPQEPKFTGFVFKIQANMDPRHRDRIAFVRVCSGRFERGMKLLHVSAGKTVAINNAITFMAQDRNTTEEAYAGDIIGVPNHGTIRLGDVFTEGEPLKFTGIPSFAPEFFRRARLNNPLKVKQLQKGLQQLAEEGATQMFRPLASNDLVLGAVGILQFDVVAHRLEHEYGVDAIFESHECATARWLKGTPAEIEKLIAKAGHNVALDGAGDHVYLAPSMVNLRLTQERFPELQFLETREIV
>NC_015723.1|WP_041228759.1|2670277_2672446_+|TonB-dependent-siderophore-receptor
MQPAFRLSGGAIGAALLFAQLAALPAHAADPAPVSAPAANPEATLNTVTVVGNWLENANEAKVLEHPGARTIVDRETFQEAGANNVREVLRRIPGVQVQENNGTGGSDVSLNVGVRGLTSRLSPRSTILMDGVPLAVAPYGQPQLSMAPLSLGNLETIDVVRGAGSVRYGPQNVGGIINFVTRPVPKLFAADASVSTDIYSHGGSVKTNPTAFIGGTNDNGLGGALLYSGIHGNGYRESNDHVNIDDLMLKGAYRISKTDELSAAFHYYEGRAGMPGGLTSAQYAADPFQSVRPYDNFDGRRSDFSLKYSHNDNNRKFEVLTYYTDSFRGSNIEQQGTGAQANLRRLTAAPRNYHTFAIEPRYSQLFRGESMSHEVSVGYRFLREASDEKASRTLFYTPGTVDPTTLPSPVYQSRTGGTTANAVYLDDTINVGSWTITPGLRYEFIRSYVTDNFSGARNDVSSNEPLPSLAVMYHVSDQWKLFANAGVSFGPLQYFQIAQTTNGLTPEKAKTYEVGTHFNANGWGGELTLFNIDFDDELQLRGGTGGAPDAWTNLGATTHRGVESSLRYDFGALDKSLAGLSAYATYTFTEATYNQGNFAGRDLPFYSRHVATVGMRYARNRWALNVDGFAQSKQHSPGDPSTSTSYQTAESANGALGDIPGYALLNMRLGYDFGKSAQNLKVAVGVKNVFDKRYFTRSTDNNAGKYVGMPRTFYIQASLAY

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Crispr_ID: NC_015723_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015723_3

2684259-2684415

Orphan

Consensus_repeat	Method
CGCAGAAACAGGTACGCTTCGCC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_015723_3

>merge|NC_015723|3|2684259-2684415|CRISPRCasFinder
CGCAGAAACGGGTACGGTTTGTGGGGTAGCCGCTGTGGAAAAGGCTGTGGAGCCAGCGAGTTATCCCCGCAGAAACCAGTTCGCGCCACCCGCAGATACAGGTTCGGCTCGCCGCAGATATGGGTTCGGCCTTTCGCAGAATCGAGTACGCTTGTCC

>NC_015723|3|3|2684259-2684415|CRISPRCasFinder
CGCAGAAACGGGTACGGTTTGTG	GGGTAGCCGCTGTGGAAAAGGCTGTGGAGCCAGCGAGTTATCCC
CGCAGAAACCAGTTCGCGCCACC	CGCAGATACAGGTTCGGCTCGCCGCAGATATGGGTTCGGCCTTT
CGCAGAATCGAGTACGCTTGTCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015723.1\|WP_013954096.1\|2676435_2676825_+\|hypothetical-protein	unknown	unknown	unknown
NC_015723.1\|WP_013954101.1\|2681775_2683092_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|379017
NC_015723.1\|WP_013954098.1\|2678448_2678919_-\|hypothetical-protein	unknown	unknown	unknown
NC_015723.1\|WP_189374659.1\|2679631_2680927_-\|NCS2-family-permease	unknown	unknown	gnl\|CDD\|225161
NC_015723.1\|WP_013954093.1\|2672531_2674133_-\|peptide-chain-release-factor-3	unknown	unknown	gnl\|CDD\|179105
NC_015723.1\|WP_041228759.1\|2670277_2672446_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227113
NC_015723.1\|WP_013954094.1\|2674306_2675380_-\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NC_015723.1\|WP_010811149.1\|2681427_2681631_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_015723.1\|WP_013954097.1\|2676955_2678323_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_015723.1\|WP_041228761.1\|2676086_2676290_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015723.1\|WP_041228759.1\|2670277_2672446_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227113	COG4772, FecA, Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism].	0
NC_015723.1\|WP_013954101.1\|2681775_2683092_+\|IS4-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	4.68017e-28
NC_015723.1\|WP_189374659.1\|2679631_2680927_-\|NCS2-family-permease	gnl\|CDD\|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	2.53129e-169
NC_015723.1\|WP_013954094.1\|2674306_2675380_-\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	8.15106e-50
NC_015723.1\|WP_013954093.1\|2672531_2674133_-\|peptide-chain-release-factor-3	gnl\|CDD\|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NC_015723.1\|WP_010811149.1\|2681427_2681631_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.31341e-34
NC_015723.1\|WP_013954097.1\|2676955_2678323_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	1.01011e-145

>NC_015723.1|WP_013954101.1|2681775_2683092_+|IS4-family-transposase
MLSEQVHTALELSEPASFARLSEHLPMAWIEHALAATGTASVRRRRLPAEQVVWLVIALALYRHQSIPDVLETLDLALPNDASACVSKSGIAQARERLGDKPLLWLFEQTARAWVAQDAAHYKWKGLALYAMDGTTFRTADSPENRLHFGAQSYASGKVASYPQVRGVSLTAVPTHLVADIAFGRYGCNEMLYAKPLIERIPDDSLTIFDKGFLAAEILWGLRMGGSERHFLIPAKKNLQWELLSGSADDGIVQMKVSPQARRKNPALPETWTARAIRDEESERVLLTSLTDRRRFKAADILACYRRRWEIETSYRELKQTMLGAELTLRSRQPEGVHQEIWGALIAYNLVRLEMAKAALEARVEPTDLSFVLALRLIQGELTWAAGMAPGKLPAHLQRMRAKLQLAIVQKRRGRKCPRVVKALPKRYTVRFLRKDLN
>NC_015723.1|WP_010811149.1|2681427_2681631_+|cold-shock-protein
MQTGIVKWFNDAKGFGFIKPDAGGDDLFAHFSEIRADGFKSLQENQRVQFEVKNGPKGLQAANITPL
>NC_015723.1|WP_189374659.1|2679631_2680927_-|NCS2-family-permease
MIERLFRLREHQTDVRTEILAGVTTFLTMAYIIFVNPSILGDAGMPKDAVFVATCLAAAIGTLIMGFYANYPIAMAPGMGLNAYFAYTVVKGMGFAWEAALGAVFISGCLFLLVTLFRVREMIVNGIPHSIRVAITAGIGLFLAIVALKNAGIVTASPATLVTIGDLHQPSAVLAIIGFFVIVALDHLRVKGAILIGILLTTLLSFAFAGNTFHGVFSAPPSLSPTLFKLDISAALSIGIINVVLVFFLVELFDATGTLMGVANRAGLLKAGKMDRLNKALMSDSTAIMAGSFLGTSSTTAYIESASGVQAGGRTGLTAVTVAVLFLAALFIAPLAGTVPAYATAPALLYVSCLMLRELLEVDWNDVTEVVPAVMTALGMPFTYSVANGVAFGFISYAALKLLTGRARSVPVMVWIIAAVFIFKFYYLPGH
>NC_015723.1|WP_013954098.1|2678448_2678919_-|hypothetical-protein
MTAGEIRRPAIGPVRETNNRSIRSIHHAWAAVGEAAGEAPSKRAVQEGATADVAALLAEDSELSDSARAAVANLLRRHRLLEGELARQRTLLQEWILSQLTYKTLYYQYSGQSPQAPRLELMREKETVRRRIRDQLQAGADYLAAPDEQLRSLSSS
>NC_015723.1|WP_013954097.1|2676955_2678323_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MDRLCKASRTAQIVVVSRHEDFGFDPSGSATGWEIRRVQQIRDLERVVRACPPMAGVIDLQSDYSDAEFAQLEQALQYLHITWVAITSDEMLAQERVRRLIRDYCVDYVRMPFSMPELLYTLKHAQGMASLHGVRPQETASRGTMIGECAAMRAMFRSLAKVAHNEAPVFISGESGTGKELAAQAIHDASSRRKGPFIAINCGAIPSHLVQSELFGYEKGAFTGANQRKIGWIEQAQGGTLFLDEIGDLPLESQVALLRFLQQGMITRLGGHQSIPLNLRIISATHVDLVAAQADGRFRSDLFHRLCVLTLTIPALRERGEDILQLANAVLTEHGHEAHRRIRGFSACATQAMMQYAWPGNVRELINRVRRAIVMTDNRKITAEDLQLHGGAELPRKTLDAIREEAEREAIRTVMASHGFHVVPAARELNVSRVTLYRLMHKHNIRVESQPTAGE
>NC_015723.1|WP_013954096.1|2676435_2676825_+|hypothetical-protein
MTAGMLAATVLAVFSSSAAAASYAWFDRPEAASANSHAAVSNDVYVRGFGWAWGELQLSPDTSSGAAMPTPGRQARDKPERGAIVPWRQQDENGPPRHPRGKLSMNLAAEPMDAASGGSGASQPRAVVR
>NC_015723.1|WP_041228761.1|2676086_2676290_+|hypothetical-protein
MTARRRSYRLAGPPPSVVDLLSSPLLPHPRARTPPAAPAAQGAGCAATARQGVARTAFRRHAGKRRA
>NC_015723.1|WP_013954094.1|2674306_2675380_-|YihY/virulence-factor-BrkB-family-protein
MRSMMNARALAAQTVTRRHAQRTRDPPGASRQHQAVTDNTERPSTSAGNAAPQPRRRRPHWLPDRHTGTRTLRVVAAAINSWFAHRAASKGAALSFYMLFSLAPILVLVISIAGLFFGAEAARGEIFSQLEGLVGEQGAAAIQEILAATHRAGGSGMAALVATAILFVGATSAFAELKSSLDDIWHVPVPATAGWQQLLRARLLSFSLVLVLAFMLLVSLIVNAALAVVERLWGQLWTQSWFAPVADVISTAFSFAVVTALFAVIFKMLPNARIAWRDVTMGAVITALLFSVGKRLIGLYLGNSAVASSYGAAGSVVALMLWVYYSAQIFFFGAELTRQYALQFGSLRGKPADKLAE
>NC_015723.1|WP_013954093.1|2672531_2674133_-|peptide-chain-release-factor-3
MSSLVSEIARRRTFAIISHPDAGKTTLTEKLLWFGGAIQVAGEVRARKADRHATSDWMELEKQRGISVTSSVMQFPYRRETANGKAQENIVNLLDTPGHEDFSEDTYRTLTAVDSAVMVIDSVNGVEAQTIKLLNVCRLRDTPILTFINKLDREGRSPIELLDEIEEVLQIQCAPMTWPIGMGKAFRGVYHLIDDKVQLFDPHGEKGTAAILDGLDNPELDRILGSQAEELRIEIELVRGASHTFDKDAFLNGKQTPVYFGSAINNFGVQSLLDALCELSPPPLARNTDSRVVEPQEPKFTGFVFKIQANMDPRHRDRIAFVRVCSGRFERGMKLLHVSAGKTVAINNAITFMAQDRNTTEEAYAGDIIGVPNHGTIRLGDVFTEGEPLKFTGIPSFAPEFFRRARLNNPLKVKQLQKGLQQLAEEGATQMFRPLASNDLVLGAVGILQFDVVAHRLEHEYGVDAIFESHECATARWLKGTPAEIEKLIAKAGHNVALDGAGDHVYLAPSMVNLRLTQERFPELQFLETREIV
>NC_015723.1|WP_041228759.1|2670277_2672446_+|TonB-dependent-siderophore-receptor
MQPAFRLSGGAIGAALLFAQLAALPAHAADPAPVSAPAANPEATLNTVTVVGNWLENANEAKVLEHPGARTIVDRETFQEAGANNVREVLRRIPGVQVQENNGTGGSDVSLNVGVRGLTSRLSPRSTILMDGVPLAVAPYGQPQLSMAPLSLGNLETIDVVRGAGSVRYGPQNVGGIINFVTRPVPKLFAADASVSTDIYSHGGSVKTNPTAFIGGTNDNGLGGALLYSGIHGNGYRESNDHVNIDDLMLKGAYRISKTDELSAAFHYYEGRAGMPGGLTSAQYAADPFQSVRPYDNFDGRRSDFSLKYSHNDNNRKFEVLTYYTDSFRGSNIEQQGTGAQANLRRLTAAPRNYHTFAIEPRYSQLFRGESMSHEVSVGYRFLREASDEKASRTLFYTPGTVDPTTLPSPVYQSRTGGTTANAVYLDDTINVGSWTITPGLRYEFIRSYVTDNFSGARNDVSSNEPLPSLAVMYHVSDQWKLFANAGVSFGPLQYFQIAQTTNGLTPEKAKTYEVGTHFNANGWGGELTLFNIDFDDELQLRGGTGGAPDAWTNLGATTHRGVESSLRYDFGALDKSLAGLSAYATYTFTEATYNQGNFAGRDLPFYSRHVATVGMRYARNRWALNVDGFAQSKQHSPGDPSTSTSYQTAESANGALGDIPGYALLNMRLGYDFGKSAQNLKVAVGVKNVFDKRYFTRSTDNNAGKYVGMPRTFYIQASLAY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015723_1	1.1\|2683688\|23\|NC_015723\|CRISPRCasFinder	2683688-2683710	23	KC170285	Uncultured bacterium plasmid pMBUI2, complete sequence	27480-27502	2	0.913

1. spacer 1.1|2683688|23|NC_015723|CRISPRCasFinder matches to KC170285 (Uncultured bacterium plasmid pMBUI2, complete sequence) position: , mismatch: 2, identity: 0.913

gagcagggcacaacgtcatggca	CRISPR spacer
gagcagggcacagcgccatggca	Protospacer
************.**.*******

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015726

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_015727

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_015723

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection