CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015733	Pseudomonas putida S16, complete sequence	3 crisprs	WYL,DEDDh,RT,csa3,casR,DinG,cas3	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015733_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015733_1

1190745-1190845

Orphan

Consensus_repeat	Method
AGTCCGTCCGTATTACTAATGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015733_1

>merge|NC_015733|1|1190745-1190845|CRISPRCasFinder
AGTCCGTCCGTATTACTAATGGCGAAGCCCCTGCGCTTTTGGCGGCGCTCCGTCCAAGCTGATGGTCTAGGTGTTCAAAGTCCGTGCGTATTACTAATGGC

>NC_015733|1|1|1190745-1190845|CRISPRCasFinder
AGTCCGTCCGTATTACTAATGGC	GAAGCCCCTGCGCTTTTGGCGGCGCTCCGTCCAAGCTGATGGTCTAGGTGTTCAA
AGTCCGTGCGTATTACTAATGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015733.1\|WP_031325854.1\|1200150_1200585_+\|hypothetical-protein	unknown	unknown	unknown
NC_015733.1\|WP_038410353.1\|1183409_1184621_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271182
NC_015733.1\|WP_038408924.1\|1194902_1195274_+\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|184361
NC_015733.1\|WP_013971149.1\|1199030_1199975_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_015733.1\|WP_080563743.1\|1198166_1198331_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_015733.1\|WP_013971144.1\|1191072_1191393_-\|hypothetical-protein	unknown	unknown	unknown
NC_015733.1\|WP_010951896.1\|1188734_1189091_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551
NC_015733.1\|WP_049798428.1\|1184751_1185777_+\|hypothetical-protein	unknown	unknown	unknown
NC_015733.1\|WP_013971137.1\|1178525_1179281_+\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_015733.1\|WP_013971148.1\|1195818_1197291_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|380294
NC_015733.1\|WP_013971145.1\|1191395_1192982_-\|P-type-conjugative-transfer-protein-TrbL	unknown	unknown	gnl\|CDD\|131830
NC_015733.1\|WP_038408920.1\|1186002_1186953_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|129804
NC_015733.1\|WP_080563740.1\|1193175_1194015_-\|P-type-conjugative-transfer-protein-TrbJ	unknown	unknown	gnl\|CDD\|131827
NC_015733.1\|WP_013971139.1\|1181524_1183102_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NC_015733.1\|WP_144241748.1\|1197279_1198155_-\|hypothetical-protein	unknown	unknown	unknown
NC_015733.1\|WP_013971138.1\|1179976_1181446_+\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
NC_015733.1\|WP_013971142.1\|1187183_1188716_-\|IS66-like-element-ISPpu15-family-transposase	unknown	unknown	gnl\|CDD\|376980
NC_015733.1\|WP_003257977.1\|1179332_1179890_+\|hypothetical-protein	unknown	unknown	unknown
NC_015733.1\|WP_080563739.1\|1189150_1189303_+\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|283558
NC_015733.1\|WP_080563741.1\|1194236_1194602_-\|TraK-oriT-binding-protein	unknown	unknown	gnl\|CDD\|379959

Protein	Function_ID	Function_description	E-value
NC_015733.1\|WP_038410353.1\|1183409_1184621_+\|site-specific-integrase	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.37246e-59
NC_015733.1\|WP_038408924.1\|1194902_1195274_+\|CopG-family-transcriptional-regulator	gnl\|CDD\|184361	PRK13877, PRK13877, conjugal transfer transcriptional regulator TraJ.	1.73885e-24
NC_015733.1\|WP_013971149.1\|1199030_1199975_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.21552e-24
NC_015733.1\|WP_080563743.1\|1198166_1198331_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.75666e-11
NC_015733.1\|WP_038408920.1\|1186002_1186953_-\|hypothetical-protein	gnl\|CDD\|129804	TIGR00721, Tfx_protein, DNA-binding protein, Tfx family. PSI-BLAST starting with one member of this family converges with significant hits only to other members of the family, which is restricted to the Archaea. Homology is strongest in the helix-turn-helix-containing N-terminal region. Tfx from Methanobacterium thermoautotrophicum is associated with the operon for molybdenum formyl-methanofuran dehydrogenase and binds a DNA sequence near its promoter. [Regulatory functions, DNA interactions].	0.00107867
NC_015733.1\|WP_010951896.1\|1188734_1189091_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	6.17683e-43
NC_015733.1\|WP_080563740.1\|1193175_1194015_-\|P-type-conjugative-transfer-protein-TrbJ	gnl\|CDD\|131827	TIGR02780, TrbJ_protein, P-type conjugative transfer protein TrbJ. The TrbJ protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer. TrbJ is a homolog of the F-type TraE protein (which is believed to be an inner membrane pore-forming protein, TIGR02761) as well as the vir system VirB5 protein.	6.54579e-51
NC_015733.1\|WP_013971137.1\|1178525_1179281_+\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.69754e-11
NC_015733.1\|WP_013971145.1\|1191395_1192982_-\|P-type-conjugative-transfer-protein-TrbL	gnl\|CDD\|131830	TIGR02783, probable_conjugal_transfer_protein_TrbL, P-type conjugative transfer protein TrbL. The TrbL protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer. TrbL is a homolog of the F-type TraG protein (which is believed to be a mating pair stabilization pore-forming protein, pfam07916) as well as the vir system VirB6 protein. [Cellular processes, Conjugation].	7.56039e-66
NC_015733.1\|WP_013971139.1\|1181524_1183102_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_015733.1\|WP_013971138.1\|1179976_1181446_+\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NC_015733.1\|WP_013971142.1\|1187183_1188716_-\|IS66-like-element-ISPpu15-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.96949e-130
NC_015733.1\|WP_013971148.1\|1195818_1197291_+\|N-6-DNA-methylase	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	3.81311e-22
NC_015733.1\|WP_080563739.1\|1189150_1189303_+\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|283558	pfam05930, Phage_AlpA, Prophage CP4-57 regulatory protein (AlpA). This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant, overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins.	6.16392e-06
NC_015733.1\|WP_080563741.1\|1194236_1194602_-\|TraK-oriT-binding-protein	gnl\|CDD\|379959	pfam17273, DUF5338, Family of unknown function (DUF5338). This is a family of unknown function which can be found mostly in Proteobacteria.	7.67926e-06

>NC_015733.1|WP_080563739.1|1189150_1189303_+|AlpA-family-phage-regulatory-protein
MECGDDGSLTKFPRRIAVSSRKVVWDLAEIEEWIDTCREFGPPPRPGMAV
>NC_015733.1|WP_010951896.1|1188734_1189091_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MRPDSKVEKVYLYPKPVDFRKSIDGLTALVELDIKVAVFDPVLFVFLNKARNRIKVLYWERNGFCLWLKRLEAERFKTSPDATDEAIVLTVQELNWLLDGFDLWRNRPHQVLTPRFVA
>NC_015733.1|WP_013971142.1|1187183_1188716_-|IS66-like-element-ISPpu15-family-transposase
MISVPDNLPDDPAALKLLLAQLLAERTVDKGQIVDLKEQVKLLRDRLFNRKSEQTVESNTPQLALFNEPESQWVPTADDADEEVVAPSKQRGKRKPLSADLPRIEVIHDLPEHELTCACGCRKHVVGEQTSEQLDIVPMQIRVLKHVRKIYGCRGCETAPVTADKPAQLIEKSMASPSVLAMLLTTKYVDGLPLHRFETVLNRHGIEIPRQTLARWVIQCSEHFQPLLNLMRDRLLESPVIHCDETRVQVLKEPDRDPTSQSWMWVQASGPPDRQVVLFDYTTSRAQEVPLRLLEGYRGYVMTDDYAGYNALALQPGVERLACMAHVRRKFVEAQKVQPKGKTGRADVALTMINKLYGIERDLKDASDEQRFIGRQERSLPILEQLKSWLDKTHSQVTPQSVLGKAVLYLANNWNRLERYVEAGHLPIDNNLAERAIKPFVIGRKAWLFSDTPKGATASAQIYSLVETAKVNGQEPYTWLRHVLERLPHASSVAAYEALLPWNCSPEMPR
>NC_015733.1|WP_038408920.1|1186002_1186953_-|hypothetical-protein
MVDMKKQTTIAIWEGCDPSVAEALHRFLDRWEPYSTASKRYAIVRLVEELIDPAVAAYVETLPSRYTGHIPGAGTNVAFSAIMQLVGVAAMVRLQRQLLRAFVLTHDKQSEDDRRFIATLETLIELVLACKRKQPSNKDLGGLNGQRLKGFCRFCGARAELALFAEGEGQRDLDEHLRLSNLYCTTHRPKTPDGRWNPAYRQAMRSVAQFDLELARLSRQCAMRAEPKAKSGDELVDAYIFRYMLSQTLHLADEAELRNLARLMVDMKLTDRRKQILVLQKFGFNQSEIARRLEIERQAVSKALRSIPDCFRLSTP
>NC_015733.1|WP_049798428.1|1184751_1185777_+|hypothetical-protein
MNVINLPSEDETLGPLMLDHIYVTEGASVKDVEGSLSPISPDEKSWDKLALSGLSLAAIATMRTTPIGLLVSAVGAAAVSPFFVQLISRYAVANAEERKQLNEAQALEAARFAAYMRKHSVTPALAEKAGFRFEPGHPLVGKVYKRHPLAGAATHDKHNLYIPSERYDQILLAEREAELIKMLVDMGATRIQISKKSAEVARSSIDGSASTDVAGYGGSSASYSSKNDQARNAMDSREFRLRGKQWHEGDRLTRADYFWLAFEPSWAAVVMAREIGACEAASLEIKETTSFSNDRNIEFQIQAQMLQAGANAQITASTKEETEYFITVEFAPAKEPRNQGA
>NC_015733.1|WP_038410353.1|1183409_1184621_+|site-specific-integrase
MLTDTKLRNLKPQDKLYKVIDRDGLYVAVTPAGSISFRYNYSINGRQETITFGRYGLGGITLAEARERLGEAKKMVAAGKSPAKEKARAKARTKGAETFDAWAEKWLRGYQMADSTRDMRRSVYERELKPKFGNQKLVEITHEDLRALTDAIVERGAPATAVHSREIVLQVFRWAIERGQKVENPADLVRPASIAKFEPRDRALTPDEIALMYQYMDRIGTATSVRAAAKLLLLTMVRKSELTNATWNEINFSEALWTIPKERMKRRNPHLVFLSQQALDFFIALKTLAGGSDYVLPSRYDSDLPMSAATINQVLTLTYRLAQKEGVPLGKFGPHDLRRTASTLLHEAGYNSDWIEKCLAHEQKGVRAVYNKAEYRDQRRAMLQDWADMIDEWTLDKPRKTNR
>NC_015733.1|WP_013971139.1|1181524_1183102_+|glutamine-hydrolyzing-GMP-synthase
MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFNPRGIILAGGPESVHEANSPRAPQAVFDLNVPVLGICYGMQTMAEQMGGKVEGSDLREFGYARVDVVGKSRLLDGIEDHIDADGVLGLDVWMSHGDKVTQMPGNFHVLASTPSCPIAGMFDDARGYYGVQFHPEVTHTKQGGRILSRFVQDICGCEALWTPSNIVEDAIAQVREQVGSANVLLGLSGGVDSSVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMAMFKENMGVKVIRADAEKQFLDNLAGEADPEKKRKIIGRTFIDVFDAEASKLENIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDFMTARWAHLPYELLETVSGRIINEIDGISRVTYDVSSKPPATIEWE
>NC_015733.1|WP_013971138.1|1179976_1181446_+|IMP-dehydrogenase
MLRISQEALTFDDILLVPGYSEVLPNEVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGGIGIIHKNMTIEQQASEVRKVKKFEAGVVKDPITIDADATVRDLFDLTRLNNISGVPVLANGDLVGIVTSRDVRFESRLDAKVRDVMTPKERLVTVREGADKNEVRELLHKHRLEKVLIVDDKFNLKGMMTVKDIEKAKAYPLASKDDQGRLRVGAAVGTGKDTGERVAALVAAGVDVVVVDTAHGHSKGVIDRVRWVKETYPQVQVIGGNIATGAAAKALAEAGADAVKVGIGPGSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIRFSGDLSKAIVAGASCVMMGSMFAGTEEAPGEVELFQGRSYKAYRGMGSLGAMAQAQGSSDRYFQDSSAGAEKLVPEGIEGRVPYKGALAAIIHQLMGGLRSSMGYTGSATIEEMRTKPEFVRITGAGMAESHVHDVQITKEAPNYRVG
>NC_015733.1|WP_003257977.1|1179332_1179890_+|hypothetical-protein
MNTQSIIVPKLSTVPVHEARARAILRWLVREKVVEEQLTTCGRTGNRMGHALAEGARKVALHPEKLPFGEQVNGLEVMLKRCIYTPTEGFLEEAGCPECRREVGEPLFESLEEWMPAVSDNFTCPLCGFEDDINGFIYLQPCAFSNLGFIFNNWGEAGFTQAFLDSFADWLDQPVAVVQVKLPQG
>NC_015733.1|WP_013971137.1|1178525_1179281_+|sulfite-exporter-TauE/SafE-family-protein
MLAQLSFSGLDWLPILLGVGAAYIVFGIAGFGTALVAGPVLIHFMPLSRIIPLLVLLDFVAAFGNLLPSRRDVVRGELLRLLPFMAIGCALGVVFLLQLKSDLLLLLMGLFVTAYALYGLAVKVRPASLSGFWAMPMGTAGGLFGALFGSGGFLYALYLSARLEVKEQVRATQSALISCSTVVRLTLFLIAGVYADQSLLLLAACLLPVMLVGLWAGRRLTHRLSREAFVRLVTWLVLASGLALIGRYLSA
>NC_015733.1|WP_013971144.1|1191072_1191393_-|hypothetical-protein
MNSILMFAGFVVLASTLAIAMWAFGRWLRSKGYGPLLDRLGRQCTALQLRVSPLALSASFHMFSGVQHLNRLPLLGSKSNAAQAQQILMAIRATQEAQRLDSPGDR
>NC_015733.1|WP_013971145.1|1191395_1192982_-|P-type-conjugative-transfer-protein-TrbL
MDTRLLLFLALASAFVSGNAMATSDLSHADTSVQGLLDLVLHQSHQWSGKLYDYAIRLFWLLASIQFIWTFIPLVMKQADFGEIVGELLRFVLVVGFFLAIMKYSVEWSSAIVDSFRDAAASASGLSRALEPGDMLAVALDFGRTMVKGISVFSPAKGLLIAVCAILVLACFAFIAAFMFVTLVESYVIINASVLFFGFGGSQWTRDFAIAPMRFTVAIGAKLFVLTLIVGLIVQSAKQWLAAYTNDEASLMTMVGLALVCCYLTKTIPDLIGGMISGTSMGGGSAIGGMAAAGAAGAAAAIATIATAGAAAPATVGALGAAGSSGAAGTGAGAAGAGGGLAGAINSSFAGASSAGGAAPAVGGATPTGVGANTGGGAVAKTASSAGVKTGGGATTQSAPPSSGTQQAAKQTGKASQSGDDNDQKATPKGGAVSSGNALSQAANGGAKALGVIASLTVPGMENAHSASLGAGPPQPAHGASSSLKSATPAAEALAMESNVIRPDTHTSSNSGGTDVSSITSSNDHPEK
>NC_015733.1|WP_080563740.1|1193175_1194015_-|P-type-conjugative-transfer-protein-TrbJ
MRNISAARFKDKTLSENISNETPASPFQKFLRQAAYSTKIVGAAFIAMAVYIASTPAYAIYCSNCSTFYQQMFEYAEAVNTALNTAEQLQTQVQQYQSMITQGTGLPDSMFGSIAADLRNVMNIYDRSQALGRQIQNMDSQFSRAFPGFNSYLNQAANSAESPAQDRFQAWSEQGRDNVKAALEAANLNTSTFETEGEQLDRMMTRSQSAVGRMQALQAGNEIASQNVQQLQKLRDLVATQINMQGNYLAQQGDRAAASEATELQFEARKNTRGGVKGY
>NC_015733.1|WP_080563741.1|1194236_1194602_-|TraK-oriT-binding-protein
MKNTPKEGLSGAGRVAFLARLEEFRVLIQAGWPVTVVYENHGGDKTSLSYSQFARYVGKYIRTPTKRGAQRARATDGTQPPTTPLLEQRQSTHPTQPSTMSKRQPGFQHDPSSGNNRDDLI
>NC_015733.1|WP_038408924.1|1194902_1195274_+|CopG-family-transcriptional-regulator
MTEDTKGKAQPRRRGKPIEVWVTDEEKATITERAEEAGMSRSGYLRALGLNTPMRSVVDLKAVSDLAKVNGDLGRAAGLLKLWLVKRPGGGIRPINLDALISDFRTLQSQILNLMSQIVNNKK
>NC_015733.1|WP_013971148.1|1195818_1197291_+|N-6-DNA-methylase
MKKQILKQYFTDAPEIKSLMCQLLGDVTNLSVLEPSVGHGSFLSGLIGSPSKIDAVDVDADALNVTRQRFGHLNLSLHHKDFIRIFDGDLLTGYDAICETLYDAVISNPPYGLYFDLDYRRQLKKRYPNFYVKESYGLFFMLSILRLKENGRYVFIVPDTFLTSVSHKPLREFIVSAAAPTHIIRFSSRRFETVNFGYGNLCIIAGDRKSLDTTGSVYWADLFDDELPLNLTSVLQSSVASKDLVRGVSTGWSSGMLVEEGRDSANHTVLGDIAECRTGIYTGDNERFIGFDPRRIPRRINGHPIPWEEVKSDKLTAAEMETGIKSGKAYVPLIRGGHRQPFEQPSSAVHWSEESVSFYKTNKKARLQNSSFYFRRGISVPMVSTSRISAALMENAVFDQGVVGIFPKEERDIPFLLIYLNSSIASRKVKEITNGSANNSANYLKRLAVPKLTEEQYRVAAEIYAKAKTDNALPQDVCDKFIESLDVLPL
>NC_015733.1|WP_144241748.1|1197279_1198155_-|hypothetical-protein
MTLDLNKLKFDILDNFHRDLRPAVDEISRLNIEHQKKAQAVNSLAGQIRNAWINWIASLPTTDRTNASLVLQYCYSVASLEYRNKVWPYEYMAFSRRVGELWEGFCSAAWNFPNRANVQRFSHPHFDDVRRTLRARLDSNIGGHARKTELQADIDILFDIIGDINMREDEVFEVDGIPHVIDFKSGFGSNEKGNMLRLQTVGRAYKLWNLNTRLLLLVRQSTNNNYLRVLQNLGLWEVHTSDNAYNLISELTGADIQQVRRMIIDWEHDLSPEFINHLSEQTTDLRAYLEW
>NC_015733.1|WP_080563743.1|1198166_1198331_-|helix-turn-helix-transcriptional-regulator
MSAGLSQEQLANLCDLDRTYIGGIERGERNPALKNIYRLAKALDVSLSNLFESI
>NC_015733.1|WP_013971149.1|1199030_1199975_-|helix-turn-helix-transcriptional-regulator
MPSTSPYLDTDFSFDSPGSLAEAGVLDSRKARIMGSATGHYRAQTVHTGLQYFDCNLQFPEPLKIDKVLPQSLCIVQLFDGAWQHKVDGTLNRYTPGQLHLLGLGESLEAQDQLPADSHARMAGVRIAGDYLHELARDEAQLIPLLALTADGMRFDQLPHCPAVSRLLQQLYLSPYTGGLRRLHCESLSLAIVLELARHLIGPAQATSRPDRGLRDLAIEARRLLDAQLSAPPTAASLARQLGVGETTLRRAFREEFGRPILQYVRQQRLELARSLLLQRLWQVSQVAYHVGYANPANFCHAYKAYFGHPPGSE
>NC_015733.1|WP_031325854.1|1200150_1200585_+|hypothetical-protein
MFAYRKWVALLVASLIFWLSQAHAEQRPDVAEQVVAYMGTEGVKVWTLRIGERAANEALVQIEGVDHDWDMRIQKMQVEKTTKDTRYSTTVDGKKFVVLVVQSGWGGELYLPGEPQPMQVGYSEGLSRQGNAQAFLTDYLAKQQ

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Crispr_ID: NC_015733_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015733_2

2358288-2358392

Orphan

Consensus_repeat	Method
CATCGAGGGTGGCGACGGCAACGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015733_2

>merge|NC_015733|2|2358288-2358392|CRISPRCasFinder
CATCGAGGGTGGCGACGGCAACGACCAACTGCGTGGTGGTGCCGGCGACGACATCATCAGCGACATGGGTGGTGACGACAACATCCAGGGTGGCGACGGCAACGA

>NC_015733|2|2|2358288-2358392|CRISPRCasFinder
CATCGAGGGTGGCGACGGCAACGA	CCAACTGCGTGGTGGTGCCGGCGACGACATCATCAGCGACATGGGTGGTGACGACAA
CATCCAGGGTGGCGACGGCAACGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015733.1\|WP_013972066.1\|2361918_2362527_-\|L(+)-tartrate-dehydratase-subunit-beta	unknown	unknown	gnl\|CDD\|236192
NC_015733.1\|WP_013972069.1\|2365010_2365922_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176168
NC_015733.1\|WP_013972057.1\|2337737_2339150_+\|amino-acid-decarboxylase	unknown	unknown	gnl\|CDD\|215475
NC_015733.1\|WP_013972067.1\|2362523_2363423_-\|L(+)-tartrate-dehydratase-subunit-alpha	unknown	unknown	gnl\|CDD\|181309
NC_015733.1\|WP_013972059.1\|2340948_2342856_+\|sugar-phosphate-isomerase/epimerase-and-4-hydroxyphenylpyruvate-domain-containing-protein	unknown	unknown	gnl\|CDD\|225726
NC_015733.1\|WP_038409303.1\|2345961_2347290_-\|TolC-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|273829
NC_015733.1\|WP_013972058.1\|2339284_2340658_-\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NC_015733.1\|WP_044046962.1\|2367685_2370202_+\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|223288
NC_015733.1\|WP_031325771.1\|2345007_2345871_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_015733.1\|WP_013972061.1\|2343629_2344991_-\|chromate-efflux-transporter	unknown	unknown	gnl\|CDD\|273350
NC_015733.1\|WP_013972071.1\|2366811_2367510_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|380375
NC_015733.1\|WP_013972070.1\|2365983_2366469_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238245
NC_015733.1\|WP_013972073.1\|2370209_2375009_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|339245
NC_015733.1\|WP_013972074.1\|2375332_2376259_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|366166
NC_015733.1\|WP_013972065.1\|2348638_2350375_-\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NC_015733.1\|WP_024086774.1\|2342933_2343602_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|372616
NC_015733.1\|WP_013972068.1\|2363477_2364815_-\|dicarboxylate/amino-acid:cation-symporter	unknown	unknown	gnl\|CDD\|234968
NC_015733.1\|WP_013972075.1\|2378076_2378502_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319916
NC_015733.1\|WP_013972064.1\|2347291_2348632_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NC_015733.1\|WP_013972056.1\|2336611_2337556_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109

Protein	Function_ID	Function_description	E-value
NC_015733.1\|WP_013972066.1\|2361918_2362527_-\|L(+)-tartrate-dehydratase-subunit-beta	gnl\|CDD\|236192	PRK08228, PRK08228, L(+)-tartrate dehydratase subunit beta; Validated.	1.91646e-150
NC_015733.1\|WP_013972069.1\|2365010_2365922_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176168	cd08479, PBP2_CrgA_like_9, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 9. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.94402e-112
NC_015733.1\|WP_013972057.1\|2337737_2339150_+\|amino-acid-decarboxylase	gnl\|CDD\|215475	PLN02880, PLN02880, tyrosine decarboxylase.	9.95656e-143
NC_015733.1\|WP_013972067.1\|2362523_2363423_-\|L(+)-tartrate-dehydratase-subunit-alpha	gnl\|CDD\|181309	PRK08230, PRK08230, tartrate dehydratase subunit alpha; Validated.	0
NC_015733.1\|WP_013972059.1\|2340948_2342856_+\|sugar-phosphate-isomerase/epimerase-and-4-hydroxyphenylpyruvate-domain-containing-protein	gnl\|CDD\|225726	COG3185, COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only].	1.42007e-142
NC_015733.1\|WP_038409303.1\|2345961_2347290_-\|TolC-family-outer-membrane-protein	gnl\|CDD\|273829	TIGR01844, Proteases_secretion_protein_PrtF, type I secretion outer membrane protein, TolC family. Members of this model are outer membrane proteins from the TolC subfamily within the RND (Resistance-Nodulation-cell Division) efflux systems. These proteins, unlike the NodT subfamily, appear not to be lipoproteins. All are believed to participate in type I protein secretion, an ABC transporter system for protein secretion without cleavage of a signal sequence, although they may, like TolC, participate also in the efflux of smaller molecules as well. This family includes the well-documented examples TolC (E. coli), PrtF (Erwinia), and AprF (Pseudomonas aeruginosa). [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Porins].	1.0467e-80
NC_015733.1\|WP_013972058.1\|2339284_2340658_-\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.1829e-153
NC_015733.1\|WP_044046962.1\|2367685_2370202_+\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	2.50817e-20
NC_015733.1\|WP_031325771.1\|2345007_2345871_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	3.2347e-54
NC_015733.1\|WP_013972061.1\|2343629_2344991_-\|chromate-efflux-transporter	gnl\|CDD\|273350	TIGR00937, Chromate_transport_protein, chromate transporter, chromate ion transporter (CHR) family. Members of this family probably act as chromate transporters, and are found in Pseudomonas aeruginosa, Alcaligenes eutrophus, Vibrio cholerae, Bacillus subtilis, Ochrobactrum tritici, cyanobacteria and archaea. The protein reduces chromate accumulation and is essential for chromate resistance. [Transport and binding proteins, Anions].	1.01681e-58
NC_015733.1\|WP_013972071.1\|2366811_2367510_-\|pirin-family-protein	gnl\|CDD\|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	2.156e-75
NC_015733.1\|WP_013972070.1\|2365983_2366469_+\|cysteine-hydrolase	gnl\|CDD\|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	4.7797e-18
NC_015733.1\|WP_013972073.1\|2370209_2375009_-\|hypothetical-protein	gnl\|CDD\|339245	pfam14496, NEL, C-terminal novel E3 ligase, LRR-interacting. This NEL or novel E3 ligase domain is found at the C-terminus of bacterial virulence factors. Its sequence is different from those of the eukaryotic HECT and RING-finger E3 ligases, and it subverts the host ubiquitination process. At the N-terminus of the family-members there is a series of LRR repeats, and the NEL domain interacts with the most N-terminal repeat. The key residue for the ligation step is the cysteine, eg found at position 386 in UniProtKB:E7K2H2. The LRR section sequesters this active site until invasion has occurred.	1.10389e-40
NC_015733.1\|WP_013972074.1\|2375332_2376259_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.62697e-19
NC_015733.1\|WP_013972065.1\|2348638_2350375_-\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NC_015733.1\|WP_024086774.1\|2342933_2343602_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.99644e-12
NC_015733.1\|WP_013972068.1\|2363477_2364815_-\|dicarboxylate/amino-acid:cation-symporter	gnl\|CDD\|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	0
NC_015733.1\|WP_013972075.1\|2378076_2378502_+\|VOC-family-protein	gnl\|CDD\|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.97651e-49
NC_015733.1\|WP_013972064.1\|2347291_2348632_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	1.53397e-113
NC_015733.1\|WP_013972056.1\|2336611_2337556_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.2536e-59

>NC_015733.1|WP_013972065.1|2348638_2350375_-|type-I-secretion-system-permease/ATPase
MHKPPRTRSELADVLFRLRRSFFALAAFSGVINVMMLTPAIYMLQVYDRALVSRNVTTLTMLTLLVIGLFMLMSALEMVRTRVLIRVGNFLDMDLNRRIFSAAFERNLSRAGGNPAQALQDLAQVRQFLTGNGLFAFFDAPWTPIYLLVCYLIHPLLGLITLIGSLILVGLAYLTEKATQKPLAEANQAALSSASYANNNLRNAEVIEAMGMLPAIGKRWFQGHLRILQMQTLASDRAAIISSTGRFVRITLQSVILGAGALLAIEGKITPGMMIACSILTGRALAPVEQVIAAWKQLQGSRCAWGRLNDLLHDYPQRPPSMSLQRPMGMLAVENVVAGAPGTSNSIVRGVSFSLVPGESLGIIGPSASGKSTLARLLVGVWPTQAGKVRLDGADIFTWNKAELGPWLGYLPQDVELFEGTIAENIARFAEVDSEAVIRAARSSGVHDMILRFPQGYDTRLAADGSPLSGGQKQRIALARALYGEPNLVVLDEPNANLDDVGEKALVDALAELKARGATVILISHRPNVLCAVDKVLMLRDGAVHMLGSRDEVFAALRKASVIPTATAAPLASVKVRE
>NC_015733.1|WP_013972064.1|2347291_2348632_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MQMTQHTELIPAEARHEIDLDIHRPARWGVWLVVAGFGGFLLWSGLAPLDAGVVATGTVKVSSNRKAVQHLTGGTVEAILVREGDVVKKGQEVVRLDALRAVAEQGAVSAQYIVSKTVENRLEAERDGRDQVTFDPALLKHYGGDPRLLAAMDLQQRLLDTRRAGLAGELSILEENLAATAVQLKGLQQVYGARASQIGFLNQELQGTRVLAAEGYVPRNRLLELERNNADLSAGQAENLNNIARARSQATEIKLRILQRQHDYLKEVESQLTDTAKENTTLADRLRALDYEVTHTVIRSPIDGMVQALSIATVGGIIQPGAKIMEVVPLDQPLQVDAMIPVQAIDKMVPGLDVDLAFPAFNHAKTPNIPGRVKTISADRLMDEESKQPYYLAQVEVTQDGMALLGSNHIRPGMPATVTIKTGERNLLSYLLKPMLERVDASFKEQ
>NC_015733.1|WP_038409303.1|2345961_2347290_-|TolC-family-outer-membrane-protein
MNRPCLMLCLLGLSVQASAMDLKQAWDLLQYQGPIYRAAVHEKEAGSENRAIGQAGLLPQINAVGYFNKVNGSQRQSGRDNDLDYDSKGANVRLRQPLFNKQKMAEYHQGQQRADYSVAVFDAKTQDAAVRLADAYFDVLLASETITLAKAKLNAFEEQLASAKRRMELGAGTITDIDESIARRDLAEADLIEAQDNLVNARRKLEEYIGETPESLTTLQPGFNTPPLMPGNLQDWLVKAQADSPLIHARRHNYELAEEEVKRARAGHWPTLDFVAGYTAGSSQSISELNQRNHYSSIGLELNIPLYSGGSTSALTRQASANSSKALDELDATRQEVISDTTREYRGVQSGALRIQALEKAVASNERSLRSARKGFREGGTSTNSDVLNAEELLFDARHDLFEAKLNYLMSRLRLASSVGSLGDDDIQQINDYLGPELVVSN
>NC_015733.1|WP_031325771.1|2345007_2345871_-|GGDEF-domain-containing-protein
MPVDLQALYPRLIHLMLDTVFVVDRGNQIIFVSDACEALLGYQACELIGTPITDYMHPDDLAITRASIVRVMNGQPHYDFRNRYIRKDGSIVHILWSASWSDEANARIGVARDITAQHQAEEELRFLAHHDPLTRLANRAMFNERLGTALVAARHHNHPLALLFIDINDFKDINDNHGHSVGDRVLCILARRLEGCVGATDTVARMGGDEFTVLLTDYASPEAIAEQVARILAAMAEPLGAEFAGIGAPSCSIGVARFPEDGNDADMLLRHADGDMYRIKRQRAAAS
>NC_015733.1|WP_013972061.1|2343629_2344991_-|chromate-efflux-transporter
MTEHLQGAAEQTRGHISRIEALLFWLKLGFISFGGPAGQIAIMHQELVERRRWISERRFLHALNYCMLLPGPEAQQLATYIGWLMHRTWGGVIAGTLFVLPSLFILIGLSWVYLAWGEVPVVAGIFYGIKPAVTAIVVHAAHRIGTRALKNGWLWAIAAASFVAIFALDVPFPLIVLAAALLGHVGGRLLPGQFAPGGGHGATRASQGPAVIDDDTPAPEHTRFSWGRLLGLLLVGAALWLLPMGVLMATFGWQGTLTQMGWFFTKAALLTFGGAYAVLPYVYQGAVGHYGWLSPTQMIDGLALGETTPGPLIMVVAFVGFVGGYLHPMFGTDQAFMAGAVAASLVTWFTFLPSFLFILAGGPLVESTHNELKFTAPLTGITAAVVGVILNLALFFGYHVLWPAGFDGRFDWPSALIALAAAVALFRYKRGVIQVLIACALAGLATHLLTGAQ
>NC_015733.1|WP_024086774.1|2342933_2343602_-|class-I-SAM-dependent-methyltransferase
MRNPEDALLDSWQHNAQAWIDAVRSGSIESRRQVTDQAILLAILGRQPERVLDLGCGEGWLLRALGDRGVEAVGVDGDRALVDAARAAGSAEVHLASYAQLAAGQAYVGKDYDLICANFALLQQDIIPLLVAMNALLAPGGALVIQTLHPWSVADGDYQDGWREESFAGFGGDWQVMPWYFRTLASWLNALDMAGLRLVSLQEPQHPQSALPQSLLLVAERP
>NC_015733.1|WP_013972059.1|2340948_2342856_+|sugar-phosphate-isomerase/epimerase-and-4-hydroxyphenylpyruvate-domain-containing-protein
MQRSIATVSLSGTLPEKLEAIAAAGFDGVEIFENDLLYYAGSPRQVRQMCADLGIAITLFQPFRDFEGCRRDRLQKNLDRAERKFDLMQELGTDLVLVCSNVQADALGEEQLLLDDLRLLAEHAGKRGLRIGYEALAWGRHVNTYQQVWNLVRQADHPALGVILDSFHTLSLKGDPSAIRDIPGDKIFFVQMADAPILAMDVLEWSRHFRCFPGQGEMDMAGFLAPILATGYRGPLSLEIFNDGFRAAPPRQNAADGLRSLLYLEEHTRLRLEQEGTSIEPGVLFTPPAASAYDGVEFLEFAVDEAVGARLGSWLKRLGFADAGKHRSKEVQLLRQGDINIVLNAEPYSFGHNFFEAHGPSLCATALRVKDQQAALKRATAFRGQPFRGLVGPNECEVPAVRAPDGSLLYLVEQGTAGQTLYDTDFSLDKNATATGGLRRIDHMALALPAESLDSWVLFYKSLFDFEADDEVVLPDPYGLVKSRALRSQCGTLRLPLNISENRNTAIAHALSSYRGSGVHHIAFDCDDIFREVARAKLAGVPLLEIPLNYYDDLAARFDFDDEFLSELAYYNVLYDRDAQGGELFHVYTEPFEERFFFEIIQRKGGYAGYGAANVAVRLAAMAKARSGAARKPVL
>NC_015733.1|WP_013972058.1|2339284_2340658_-|MHS-family-MFS-transporter
MAHSSSQAKKATASGWIGSALEYYDFFIYAQAAALIFPQIFFPNTDPKMAIIASLATYGVGYLARPVGAFVLGHWGDTRGRKNVLLLCMFLMGLSTMAVGLLPTYHDIGLLAPALLVVLRLVQGFAVAGEISGASSMIMEHAPFGRRGYYASFTLQGVQAGQVLAAAVFLPLAYFMPSEAFNDWGWRIPFLLSAFVLIAGFIIRKEVHETPAFVKEEKQDKVAKSPISEAFRHSWKHMVLVMFMALMNVIPVVATIFGAAYAVQPAYGIGFDKSVYLWIPVVGNIVAVLVIPFVGNLSDKIGRRPTMIAGCLGSGLLAFVYLYAISIQNVPLAFASSIVMWGMVYQGYNAVFPSFYPELFHTRYRVSAMAIAQNIGTMLTAMLPALFALVAPPGSDNIPLVVGSLAFFITCVCALAAYIAPETHRLAMEDLGNPDAKPMDKTAYEASRKGSFQAVSN
>NC_015733.1|WP_013972057.1|2337737_2339150_+|amino-acid-decarboxylase
MTPEQFRQYGHQLIDLIADYRQTVGERPVMAQVEPGYLKAALPAQAPRQGEPFAAILDDVNQLVMPGLSHWQHPDFYGYFPSNGTLSSVLGDFLSTGLGVLGLSWQSSPALSELEETTLDWLRQLLGLSGQWSGVIQDTASTSTLVALICARERASDYALVRGGLQAQAKPLIVYVSAHAHSSVDKAALLAGFGRDNIRLIPTDERYALRPEALQVAIEQDLAAGNQPCAVVATTGTTATTALDPLRPIGEIAQAHGLWLHVDSAMAGSAMILPECRWMWDGIELADSLVVNAHKWLGVAFDCSIYYVRDPQHLIRVMSTNPSYLQSSVDGEVKNLRDWGIPLGRRFRALKLWFMLRSEGVEALQARLRRDLDNAQWLAGQIGAAAEWEVLAPVQLQTLCIRHRPAGLEGEALDAHTKGWAERLNASGDAYVTPATLDGRWMVRVSIGALPTEREHVEQLWARLQEVVKG
>NC_015733.1|WP_013972056.1|2336611_2337556_+|LysR-family-transcriptional-regulator
MNPAFASLSLAHLRTLDHLLQLKNLSHAAERLGVSQSALSRQLAHLREAFDDPLLVRQGRGYVLSEHAEALVEPLRQVLEELHALRQPAVFDPGRCERRFCLAASDYVAEHMLPLLVAALEREAPGVSLEYRTWQAGQYALLASGEIDLATTLFDESPPNLHGRLLGEDRAVCLMRNDHPLAAHGALSQADYLSHKHVRISGGGDKDSFIDRHLRAQGLQRRVSLEVPFFSATVQVIANSQALATVPEHIARQLCRLHDLAWRPLGFIDHSQRYWVVWHQRLQASAEHRWLRNRVFELWRQSQFGVQGGHAGLP
>NC_015733.1|WP_013972066.1|2361918_2362527_-|L(+)-tartrate-dehydratase-subunit-beta
MKKILSTPISDEDLANLNVGDVVYLTGQLVTCRDVAHRRLIELGRELPVDLRGGAIFHAGPIVRKKDDGSFEMVSIGPTTSMRMEKFEKQFIEQTGVKLIVGKGGMGPETTTGCLENMAVHAVFPGGCAVLAATQVEEIERAEWQDLGMPETLWVNRVREFGPLIISIDTKGNNLFEQNKARFNERKGAVIEKINSQVRFIK
>NC_015733.1|WP_013972067.1|2362523_2363423_-|L(+)-tartrate-dehydratase-subunit-alpha
MDKETAVSSLTDVMAKFTAYIGKRLPRDVKEKTAKLRAAETNPLAIAVYDSMADNQEYADKLNRPSCQDTGVIQYFVSAGARFPLLGEMEGILENATREATIQGPLRHNAVETFIEKNTGTNTGSKIPWLDWEIIPDADYAIVDVYMAGGGCTLPGSAKVLMPGQGYEGVTEFVFDVITSRGVNACPPLLVGVGVSTSVETAARLSKKAILREVDSSHPNESAAMMEKLLEEGLNEIGIGPQGLTGNSSVMGVNIESSARHPSTIGVAVSTGCWAHRRGKIRINADLSYDILSHEGVVL
>NC_015733.1|WP_013972068.1|2363477_2364815_-|dicarboxylate/amino-acid:cation-symporter
MAKRLFGKLYVQVLIGVTLGVLIGVFWPQVGADLKPVGDAFIKLIKMVFAPIIFATVVLGIAKMENMKELGRVGVRALIYFEVLSTFALVLGLVVVNIVQPGQGMNVDPATLDAKSISTYTAAAAGNSGGFIDFLLHVIPGSVTDAFAKNEILPILLFSTLFGIALSHLGPRGKPMVDVLEAFSHGMFFIVGMIMRVAPLAACGAMAFTVGKYGLGSIVSLGKLMATMYLTCFLFVVVVLGAIARLCGFNLWKFLKYLKEELFTVLGTSSSESVVPQLMNKLEKVGVSKPVVGLVIPSGLTFNPDGQCIYYTMAAIFIAQATNTPLTLMDQLIVLGVLLLTSKGSAGVTGSGFITLAATLATMDNIPVAGMVLLLGVDRFMSEARAITNTIGNAVGTVAIANWVGALDKQRMAQALDGQLPADPEPEAAVPHPALARMEAGTPAP
>NC_015733.1|WP_013972069.1|2365010_2365922_+|LysR-family-transcriptional-regulator
MNPVSELAFFTQLIRVGSLAGTARELNLTPPAVSKRLAQLEQRLGVRLLNRTTRSISLTAEGETYLVNAKRILGEIEEMERQVSSSRAEPKGLLRVNAPLGFGRTHVGPAVSSFAKRYPEVEVQLHLTDRPIALPNDAIDVAIRFGELPDSRLIARKIAANRRRLCASPGYLEAHGTPEAPKDLASHNCIVLRQNDAAFGIWRLSRGKQSESVKVHGSLSTNDGEVALNWALDGQGILLRAEWNLADHLRSGRLVEVLGDYQTPPADIYAVYLERLNLSAKVSCFVEHLRAFFRQGDSLAAWH
>NC_015733.1|WP_013972070.1|2365983_2366469_+|cysteine-hydrolase
MRQVLLIVDVQSTFSPPEWLVDGLRRLSANIPTIASVELHDEQVTPFERQLGWHPAAEDESLVEADQVFVKHGYGQSAEAIDYIRQLGVERVLVCGLQTETCVLAAGFALFDAGLMPTLVTDMTVGSSLDRSGKLGIDLWKHHFRQVTTSAEVLAEVASRG
>NC_015733.1|WP_013972071.1|2366811_2367510_-|pirin-family-protein
MLQLRPFESLGHANHGWLDAHHHFSFAEYYDPARMHWGNLRVWNDDLIAAGSGFPPHPHRDMEIITYVREGAISHQDSLGNKGRTEAGDVQVMSAGTGIVHSEYNLEDVDTRIFQIWIVPERTGEAPQWGTRPFPKGERGEGFVTLASGRAGDEDSLQIRTDARLVAATLRAGETAEYRFDTARRGYLVPAKGLVEVNGLRAKARDGVAIEQEEVLRVTAIEDSEIVLVDVA
>NC_015733.1|WP_044046962.1|2367685_2370202_+|UvrD-helicase-domain-containing-protein
MRRTCPLILFFNGVTVAHEQPQAPADLTPPAQLPWFRRLAARLLGRGLTRLQAQHRDSWFLGHASGQRSGHADGVREGFERGRVEGYEAGRQVLVIRDTRPDTAAVPGRDDNLFDDWRLPLTAELKKRFKADVAQRLPAEAQPSAAQWKLIFSDTPSTCVVAGAGAGKSTSLVLRILLLRHYLGYELDAMTVVTFTRESRKDFIKRLLQVFALWQINLQPLQARELVRTFHSRILPLVRSLPGFGQVRAFETLGNEMPAGREAEAESNPFDLRLNDAQRQQLNQCYSTLLGESPRFAELVGLLRSEALQLKPLDPNNPDVQKRAQVTQLAAQRDEELCDVIEDLWFAAGAWPIKGIEPCRETIEIRGSRFHVHGRLAGQGPLLVLGFDPAESAQYQRPGAKLAVRAEWAVKRTLLQAFCDQPLIWLDNYAMARRLAASLAGDAVAGPGFEYKVKGELAPAPLLDAFVGAANFIENLGLEVNTAVAAMSFPSGDSDALFFEALALYWKALEAHLLDQSPPVMSYNRMFALFGENNPENLQLLPDPLLRPLAHLMIDEFQDVSPQIVSWLRASLAEIRRRGPAMHTGRHAQHSSLLCVGDDWQSIYGWRGSSPKYFMEFTKAFPSPANTRVMLVDNYRCQQQVIDAAEHLVKGTPAIAGKKARASGPAAELPGSPVKVFDRDEAALGETLIEHYQRGETVMMLYRKGSDRALMNEHLQGVLHAEAALPAEQRRLRQLTYHSAKGLQADAVFMLGDCQYLTSSPYKNQVYRQAGLGKAGDAQPFDTAQKEEVQRLAYVAVTRAVRHCYWHVEAANAEAAAAPRASSQVDGRQAFFEDLRGH
>NC_015733.1|WP_013972073.1|2370209_2375009_-|hypothetical-protein
MHPDHTRRVVQSVRKDYLDENGSPYAWYAAASDEDQARLRQLISARNAGFKALQALLDDFRQISELCKPLLEGRLGPDVEVDKAQYLHQPFKVYTTLENVPGLDFSLGGDDTYIKRPEGPPQKRSLLEAALHNFEGPDEVGPFDTLTLGTDNVASLPGLEPEAFVNLCRSLNLGQQYQDHLQGIYEGPRKAAIEQQWIDASQQALKIEAMIAYLKGLLTLKGHNALVQLCDNESTPRYGEHKLRCWRFSLFGIPLHGVLLIGPDEADQTNPCMLYIPHDSEHPVREFASLQKAGSLMRQRLVQTTFRQHLISFADQDNQVELSRKLENALFEHDASTRKPKNKPELHFKRTRLAFPIWQVLYRDHKRRVKATARAIAVPTADADAKARKERLQHWLDAGMNVLNVAAFFVPGLDAAMLGVFAYDLMDSVFTGFEAWEEGDTQEALQQLESLAINAAVIAGFAVGSKALKASGFVDALESVWKGGRERLWHPDMGPYSTSSSLPVGVQKNAQGLYIIDGKTHVWLQGKLYEVFETDGQWHVRHPDAPDAYTPALRNLGDQRWQLAHDNPLEWDDAQLLEGLGRFGQGLDASDQLAALRITEVDADTLRRSQVTGSQPPPLLADTLLRLRLADDVEGIITRVRHGQPLAAHMNFALPELVQLPGWPENYRLKVFTGAEKWGEADYFGAQPKADTVQIEIGREELDDGELSKIVLAGMDEDVIQQLLPDTPVEQRPGALNELLANHLTARRHEIFASMLESHRAPLGDEAQTLGRQFPGLPDNALEELVAHADSTERERLKNGRVPLRVAEEARYLQARARLDRALTGLYRADLANADSQLLRDALVAEQPQASEAELFASAVADRSGCAVLLGQQSIKPGFRSPMRLAHGRIGYPLSGRGAAISTSAATSRLNRLFPSLNSKQITALSDELSRTRDLGSAIQQLETEWQTLDSNLESWYKSAPDIFRRQDREKCAESLKEAWRREGSAKLGTLVLEKIQISELPAITASLPYIRELKLNDLQLQRLDRAFLSCFPNLQVLRVTNIATINPQALFEALEAVPKLQTLDLTNNTVVTLSPTAQRVLAAMPGLRELNLTGNNLTLDQATLAFLCDQPLNILKLSRNRITLDENLATRFQDMIHPQQLDLSFNSLQHAPDVRYMARLQHLDLDRTQLHAFPPGLSTLMNQRQYQLRYLNLSSNHIPNVPDLVNILRSPYVRDVAARVRDRRWLFNYNNLEAEPARQLRARGVNIFEHPPERQEWQRLWRDSATDHQVQVWSDLFDQNDNGDLQAVLERLTDSVEARRDLRSLRARVWELLEQAHGDAVLRERLNEVAKIFPPTCGDAGADAFSALEVELLIHQVSGEAQDTAKPILDLYRKLYRREKVNELADRISLQRGLRKRALQEHAGQLPDRDVLDVAAAFPDADLTTGLVDDIEVRLALRQSLSEDLDFPEPSSGMLYRDLAKINQQIIDNVRDAVVELDADTTARQLWISERPVWVDYLKRKYASQFEAITDFWRPGLDYLFYCLDESQEAITHLDKSIIRALAPEMPGLALDENGTLRRVPLSGKAYFKAMEALTKAQEEVEAGLLLSLTRQEDILDA
>NC_015733.1|WP_013972074.1|2375332_2376259_+|alpha/beta-fold-hydrolase
MHSLCSPKDHLLDLDGIEIAVRTWGAEDGIPVLALHGWLDNAASFERLAPMLDGCFVVAPDLVGHGRSDHRRHDSGYYLWEHAEDMLAVADSLGMVQFHVLAHGMGTGVASLLAAMTSGIASMTFLDGMGAPFTVAEDDRVQHLARAYRLKRMVQRSQLQGFAEPDVGRFEDLDTALAQRRERLDTELSEEAARLLALRDLLQLGEGYCWRHDPRLVLPEPMPLTEREACDLLSQIRCPLYLLFGRQGAFTGEAFTRRQAALPSQAKISWHPGGHHFHLDAPDRALVDQLLRILARHEGGVLQRLVNE
>NC_015733.1|WP_013972075.1|2378076_2378502_+|VOC-family-protein
MRPFVIKHIDHLVLRVSDLERSVAFYTQLLGCTVSRVREDLGMVHLATGTAMIDLVTLDGPLGKPGGAAPGTEGRNLHHFCLRIEPFDEAALTAYLQAAGVEVEPAEKRYGAEGEGLSLYCYDPDGNQVELKGPVPATEAP

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Crispr_ID: NC_015733_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015733_3

4259650-4259737

Orphan

Consensus_repeat	Method
AGCGCCGCGCGGGCGGCGCTCGGTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015733_3

>merge|NC_015733|3|4259650-4259737|CRISPRCasFinder
AGCGCCGCGCGGGCGGCGCTCGGTCTCACAGGCGCAGAAAGTACAACGGCAAACACTCGAGAAGCGCCGCGCGGGCGGCGCTCGATCT

>NC_015733|3|3|4259650-4259737|CRISPRCasFinder
AGCGCCGCGCGGGCGGCGCTCGGTCT	CACAGGCGCAGAAAGTACAACGGCAAACACTCGAGA
AGCGCCGCGCGGGCGGCGCTCGATCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015733.1\|WP_013973606.1\|4255754_4256087_-\|flagellar-hook-basal-body-complex-protein-FliE	unknown	unknown	gnl\|CDD\|178948
NC_015733.1\|WP_013973616.1\|4269491_4271057_-\|flagellar-hook-associated-protein-3	unknown	unknown	gnl\|CDD\|171679
NC_015733.1\|WP_013973047.1\|4266930_4267914_+\|IS5-like-element-IS2000-family-transposase	unknown	unknown	gnl\|CDD\|225581
NC_015733.1\|WP_013973607.1\|4256304_4257660_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_015733.1\|WP_044047133.1\|4263647_4263998_-\|flagellar-protein-FlaG	unknown	unknown	gnl\|CDD\|377090
NC_015733.1\|WP_013973611.1\|4261737_4262133_-\|flagellar-export-chaperone-FliS	unknown	unknown	gnl\|CDD\|235560
NC_015733.1\|WP_013973603.1\|4252004_4252787_-\|flagellar-assembly-protein-FliH	unknown	unknown	gnl\|CDD\|235562
NC_015733.1\|WP_044047132.1\|4248003_4249695_-\|fused-response-regulator/phosphatase	unknown	unknown	gnl\|CDD\|369272
NC_015733.1\|WP_013973610.1\|4261426_4261720_-\|hypothetical-protein	unknown	unknown	unknown
NC_015733.1\|WP_013973604.1\|4252948_4253968_-\|flagellar-motor-switch-protein-FliG	unknown	unknown	gnl\|CDD\|235561
NC_015733.1\|WP_013973609.1\|4259781_4261257_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_015733.1\|WP_013973601.1\|4250200_4250653_-\|flagella-biosynthesis-chaperone-FliJ	unknown	unknown	gnl\|CDD\|235563
NC_015733.1\|WP_162097114.1\|4257659_4258856_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|236901
NC_015733.1\|WP_013973612.1\|4262213_4263569_-\|flagellar-filament-capping-protein-FliD	unknown	unknown	gnl\|CDD\|236141
NC_015733.1\|WP_013973605.1\|4253960_4255739_-\|flagellar-M-ring-protein-FliF	unknown	unknown	gnl\|CDD\|235668
NC_015733.1\|WP_013973600.1\|4249703_4250009_-\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|132914
NC_015733.1\|WP_013973602.1\|4250659_4252015_-\|flagellar-protein-export-ATPase-FliI	unknown	unknown	gnl\|CDD\|168181
NC_015733.1\|WP_013973617.1\|4271070_4273113_-\|flagellar-hook-associated-protein-FlgK	unknown	unknown	gnl\|CDD\|235558
NC_015733.1\|WP_013973614.1\|4264074_4266093_-\|flagellar-biosynthesis-protein-FliC	unknown	unknown	gnl\|CDD\|236344
NC_015733.1\|WP_044047134.1\|4268140_4269070_-\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|238426

Protein	Function_ID	Function_description	E-value
NC_015733.1\|WP_013973606.1\|4255754_4256087_-\|flagellar-hook-basal-body-complex-protein-FliE	gnl\|CDD\|178948	PRK00253, fliE, flagellar hook-basal body protein FliE; Reviewed.	7.91567e-41
NC_015733.1\|WP_013973616.1\|4269491_4271057_-\|flagellar-hook-associated-protein-3	gnl\|CDD\|171679	PRK12717, flgL, flagellar hook-associated protein 3.	0
NC_015733.1\|WP_013973047.1\|4266930_4267914_+\|IS5-like-element-IS2000-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	1.04352e-33
NC_015733.1\|WP_013973607.1\|4256304_4257660_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NC_015733.1\|WP_044047133.1\|4263647_4263998_-\|flagellar-protein-FlaG	gnl\|CDD\|377090	pfam03646, FlaG, FlaG protein. Although important for flagella the exact function of this protein is unknown.	5.49807e-22
NC_015733.1\|WP_013973611.1\|4261737_4262133_-\|flagellar-export-chaperone-FliS	gnl\|CDD\|235560	PRK05685, fliS, flagellar export chaperone FliS.	5.22975e-60
NC_015733.1\|WP_013973603.1\|4252004_4252787_-\|flagellar-assembly-protein-FliH	gnl\|CDD\|235562	PRK05687, fliH, flagellar assembly protein FliH.	1.23618e-83
NC_015733.1\|WP_044047132.1\|4248003_4249695_-\|fused-response-regulator/phosphatase	gnl\|CDD\|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	6.91452e-44
NC_015733.1\|WP_013973604.1\|4252948_4253968_-\|flagellar-motor-switch-protein-FliG	gnl\|CDD\|235561	PRK05686, fliG, flagellar motor switch protein G; Validated.	4.85433e-162
NC_015733.1\|WP_013973609.1\|4259781_4261257_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	2.5186e-163
NC_015733.1\|WP_013973601.1\|4250200_4250653_-\|flagella-biosynthesis-chaperone-FliJ	gnl\|CDD\|235563	PRK05689, fliJ, flagella biosynthesis chaperone FliJ.	2.98165e-53
NC_015733.1\|WP_162097114.1\|4257659_4258856_-\|PAS-domain-containing-protein	gnl\|CDD\|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	2.11541e-52
NC_015733.1\|WP_013973612.1\|4262213_4263569_-\|flagellar-filament-capping-protein-FliD	gnl\|CDD\|236141	PRK08032, fliD, flagellar capping protein; Reviewed.	1.28595e-49
NC_015733.1\|WP_013973605.1\|4253960_4255739_-\|flagellar-M-ring-protein-FliF	gnl\|CDD\|235668	PRK06007, fliF, flagellar basal body M-ring protein FliF.	0
NC_015733.1\|WP_013973600.1\|4249703_4250009_-\|STAS-domain-containing-protein	gnl\|CDD\|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	8.81331e-19
NC_015733.1\|WP_013973602.1\|4250659_4252015_-\|flagellar-protein-export-ATPase-FliI	gnl\|CDD\|168181	PRK05688, fliI, flagellar protein export ATPase FliI.	0
NC_015733.1\|WP_013973617.1\|4271070_4273113_-\|flagellar-hook-associated-protein-FlgK	gnl\|CDD\|235558	PRK05683, flgK, flagellar hook-associated protein FlgK; Validated.	0
NC_015733.1\|WP_013973614.1\|4264074_4266093_-\|flagellar-biosynthesis-protein-FliC	gnl\|CDD\|236344	PRK08869, PRK08869, polar flagellin E.	4.4e-72
NC_015733.1\|WP_044047134.1\|4268140_4269070_-\|ketoacyl-ACP-synthase-III	gnl\|CDD\|238426	cd00830, KAS_III, Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.	1.51259e-95

>NC_015733.1|WP_162097114.1|4257659_4258856_-|PAS-domain-containing-protein
MRAPDPQGQTPVEQDSRQGVEQAFALFNQVSSQLSQSYSLLEARVSELKGELAVVSAQRIDELSEKERLANRLQNLLDLLPGGVIVIDGQGLVREANPAACELLGEPLVGQLWRQVIARSFAPRKDDGHEVSLRDGRRLSIATRSLDAEPGQLVLLNDLTETRRLQDQLARHERLSSLGRMVASLAHQIRTPLSAAMLYASHLADPGQDLGAETRQRFAGTLKERLHELEHQVRDMLVFARGELPLGDRVTPKALFQALQQAAQAHVQGHAVRWQCDSHLGELLCNRDTLIGALLNLIENALQASDGPARLKVHLFRRERSLHLCVSDAGSGIDADLLGRLGEPFLTTKATGTGLGLAVVKAVVRAHQGTLRLRSKVGRGTCVRVELPLIGGQLAEGM
>NC_015733.1|WP_013973607.1|4256304_4257660_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MTIKVLLVEDDRVLRQALGDTLEIGGFAYQAVGSAEEALEAVLEEAFSLVVSDVNMPGMDGHQLLARLRRQQPQLPVLLMTAHAAVERAVEAMRQGAADYLVKPFEPKALLSLVERHAAGRVAEEEGPVACEPASRQLLELAARVARSDSTVLISGESGTGKEVLARYIHQQSARAAQPFVAINCAAIPDNMLEATLFGHEKGAFTGAIAAQVGKFEQAEGGTLLLDEISEMPMALQAKLLRVLQEREVERVGGRKPISLDIRVLATTNRDLAGEVAAGRFREDLYYRLSVFPLAWRPLRERPGDILQLAERLLARHVAKMKHAPVRLSPQAQDCLQAYAWPGNVRELDNALQRALILQQGGVIEAADFCLAGAIPLSAGTEPSLEVVAEAGGLGDDMRRHEYQMIIDTLRAERGRRKEAAERLGISPRTLRYKLAQMRDAGFDVEASLFG
>NC_015733.1|WP_013973606.1|4255754_4256087_-|flagellar-hook-basal-body-complex-protein-FliE
MSQGVEFNRLMLDMRAMQADAMSLPKVAAAPELAPGQSTFADMLGQAIGKVHETQQASTQLANAFEIGKSGVDLTDVMIASQKASVSMQALTQVRNKLVQAYQDIMQMPV
>NC_015733.1|WP_013973605.1|4253960_4255739_-|flagellar-M-ring-protein-FliF
MAEAVVDNAPAKSGPPAAKPPLFGMAFLENIAQMPMLRQIGLMVGLAASVAIGFAVVLWSQQPDYRPLYGSLAGMDTKQVMDTLAAADIPYNVEPNSGALLVKADDLSRARLKLAAAGVAPSDGNVGFELLDKEQGLGTSQFMEATRYRRSLEGELARTVSSLNNVKGARVHLAIPKSSVFVRDERKPSASVLVELYPGRALEAGQVMAIVNLVATSVPELDKSQVTVVDQKGNLLSEQIQDTALTQAGKQFDYSRRVESMLTQRVHNILQPVLGNDRYKAEVSADLDFSAVESTSEQFNPDQPALRSEQSVDEQRASSQGPQGVPGALSNQPPGAASAPQTTGGAATPAAAIQPGQPLVDANGQQIMDPATGQPMLAPYPSDKRQQSTKNFELDRSISHTRQQQGRMTRLSVAVVVDDQVKIDPATGDTTRAPWGAEDLARFTRLVQDAVGFDASRGDSVTVINVPFAADRGEEIADIAFYQQPWFWDIVKQVLGVVFILVLVFGVLRPVLNNITGGGKQAAPDSDMELGGMMGLDGELANDRVTLGGPTSILLPSPSEGYEAQLNAIKGLVAEDPGRVAQVVKEWINADE
>NC_015733.1|WP_013973604.1|4252948_4253968_-|flagellar-motor-switch-protein-FliG
MSDNRAVTAKLSRVDKAAILLLSLGETDAAQVLRHMGPKEVQRVGVAMAQMGNVHRDQVEQVMSEFVEIVGDQTSLGVGSDAYIRKMLNQALGEDKANGLVDRILLGGNTSGLDSLKWMEPRAVADVIRYEHPQIQAIVVAYLDPDQAGEVLSNFDHKVRLDIVLRVSSLNTVQPAALKELNQILEKQFSGNSNAARTTLGGIKRAADIMNFLDSSVEGALMDAIREIDSDLSEQIEDLMFVFNNLADVDDRGIQALLREVSSDVLVVSLKGADERVKDKIFKNMSKRASELLRDDLEAKGPVRVSDVETAQKEILTIARRMAEAGEIVLGGKGAEEMI
>NC_015733.1|WP_013973603.1|4252004_4252787_-|flagellar-assembly-protein-FliH
MPTKEHHPSDLIRARDLEGVDVWALPSFDPEPEAEPEPEPEPEVVEEEVEEVPLEEVQPLTLEELEAIRQEAYNEGFATGEREGFHSTQLKVRQEAEEALKTKLESLDRLMTNLMEPIAEQDTQIEKALVHLVAHMTRQVIGRELRSDSSQITQVLREALKLLPMGADNIRIHLNPQDFELAKALRERHEESWRLLEDSALLPGGCRIETAHSRIDATMETRIEKAVAQLFDQLHDHSLHPAAADMSIDLDSLVDTPDAP
>NC_015733.1|WP_013973602.1|4250659_4252015_-|flagellar-protein-export-ATPase-FliI
MHLERTSFGKRLGSYAEAIELPAQPIVEGRLLRMVGLTLEAEGLRAAVGSRCLVINDDSYHPVQVEAEVMGFAGPKVFLMPVGSIVGIAPGARVVPLDDGGRLPMGMSMLGRVLDGAGRALDGKGGMKAEDWVPMDGPVINPLNRDPISKPLDVGIRSINGLLTVGRGQRLGLFAGTGVGKSVLLGMMTRFTEAEIIVVGLIGERGREVKEFIEHILGEEGLKRSVVVASPADDAPLMRLRAAMYCTRIAEYFRDKGKNVLLLMDSLTRFAQAQREIALAIGEPPATRGYPPSVFAKLPKLVERAGNGEPGGGSITAFYTVLSEGDDQQDPIADSARGVLDGHFVLSRRLAEEGHYPAIDIEASISRVMPQVVDADHLRQAQKFKQLWSRLSQSRDLISVGAYVAGGDPETDLAIALQSKLVEFLRQGLRENVGMAQSRDQLGAIFTPPAG
>NC_015733.1|WP_013973601.1|4250200_4250653_-|flagella-biosynthesis-chaperone-FliJ
MALPGRAARLAPVVDMAEEAERKAAQRLGQFQQQVATAQAKLAELERFREDYQLQWINRGGQGVNGSWLVNYQRFLGQLETAMTQQRQSLVWHQNNLNNARGTWQQAYARVEGLRKLVQRYLEEARRAEDKREQRLLDELSQRLPRQNHL
>NC_015733.1|WP_013973600.1|4249703_4250009_-|STAS-domain-containing-protein
MAVETDFSQDGKKLTIKIKGRFDFGKHQEFRDAYERQPSRPDSVVVDLKDTTYLDSSALGMLLLLRDHAGGDESDVRVVHASSDVRKILAISNFEKLFDIS
>NC_015733.1|WP_044047132.1|4248003_4249695_-|fused-response-regulator/phosphatase
MPAEQALTVLVAEDGAADRLLLAQIVRRQGHQVFTAENGEQAVALFVERRPQLVLLDALMPVMDGFEAARQIKALAGEALVPIIFLTSLNEEEGLVRCLEAGGDDFMAKPYSAVILGAKIRAMDRLRRLQATVLEQRDQIARHHHHLLNEQRVAKAVFDKVAHSGCLAAPNIRYLQSPYALFNGDLMLAAFTPSGDMRVLLGDFTGHGLPAAVGAMPLAEVFYGMTAKGYGMAQVLREMNAKLKRILPVDMFCCALLLNLSMQRGSVEVWNGGMPDGYRLAVDGQVLSALGSRHLPLGILDAERFDDSTEVLPLAPGERLLLLSDGVLDTADDQERLFGVQRLRRVLADNHDPARLFDEVMQALERFGGRPRDDISLCDIRMFCAEEQVPAPMIYSDSGRSSPLDWSLGFEVRGESLKRFNPVPYLVQLLQEIHGLRARTGNLHSVLSELYSNALEHGVLGLDSQLKRDGQGFADYYQERARRLGVLTDGYVRIDFKVEPHADGGRLMIEVRDSGAGFDVQGVLSRPTLEQGLSGRGLNLVRRLASSACWSEGGRCAHVEFVW
>NC_015733.1|WP_013973609.1|4259781_4261257_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MWRETKILLIDDDSARRRDLAVVLNFLGEENLACSSQDWQQVVEPLSSSREVLCVLIGTVNAPGSVLGLVKTVTGWDEFLPVLLLGEISSAEFPEDLRRRVLSNLEMPPSYSQLLDSLHRTQVYREMYDQARERGRQREPNLFRSLVGTSRAIQHVRQMMQQVADTDASVLILGESGTGKEVVARNLHYHSRRREAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSIDVRIIAATHKNLETMIEEGTFREDLYYRLNVFPIEMAPLRERVEDIPLLMNELISRMEHEKRGSIRFNSASIMSLCRHGWPGNVRELANLVERMAIMHPYGVIGVSELPKKFRYVDDEDEQMVDSLRSDLEERVAINGHTPNFSNHAMLPPEGLDLKDYLGSLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKMRKYGMSRQGGEEQAED
>NC_015733.1|WP_013973610.1|4261426_4261720_-|hypothetical-protein
MSALQQIEDTRLALSEALQARDWAAIGELDLACRALMDEVLQDEQEDEAAVRANLEALMAVYRQLIDVASDERQSLVGQMANINQAKQATKVYHLFS
>NC_015733.1|WP_013973611.1|4261737_4262133_-|flagellar-export-chaperone-FliS
MHPMRALRQYQKVNTHAQISEATPHRLVQLLMEGSLDRMAQAKGAIARGDVAQKGVMLGKAIDIIGGLREGLDKEKTDNPEELDRLDSLYDYMARRLTQANLHSDPAIIDEVAQLMITVKSGWDAIASAEQ
>NC_015733.1|WP_013973612.1|4262213_4263569_-|flagellar-filament-capping-protein-FliD
MASSTISGLGSGLDISGIVKALADAEKAPKQTQINTQTQTATTSLSAIGTVKSALDTFRAAIAKLNTASSFSGLASSSSDETIAKIKLGDGASSGNYALEVTQLATASKISTQVYEKTSTVVNDSGEAQTLTISQGSSTHSVTIANGATLQEARDTINGQLQSKGITANIVTDANGSRLIFSSTKMGEGTELTLGGDASMAADVTTIAKPQNAKYTLDGLALESASNTVTGAVSGVDITLVKEGKANLGVTSNNDTLKSSVQSFVTAYNALMTAVNAQTKVTTGSDGAATGAAALTGDATMRSLVNSVRNEITRSVGTTGLRTLSQLGINTVQKTGLLEFTDTKWDAAVKTYGADISGLFTGKEGLLTRLTNTTEDYVKTGGILESRQTNLTNQLKELAEAQTALDRRITSLTDTLTKKYNAMDTMVAQLKATSDSVMTTLNALNKSNSDD
>NC_015733.1|WP_044047133.1|4263647_4263998_-|flagellar-protein-FlaG
MDMSVKLGLSYPASAAPDVSTSKRQAHEQAASEPVDKESKPVAKAELESAVSAIQDFVKASERQLDFSIDDSTGQVVVKVIARQSGEVIRQLPTEVALKLAENLKDANSLLFDTQA
>NC_015733.1|WP_013973614.1|4264074_4266093_-|flagellar-biosynthesis-protein-FliC
MALTVNTNITSLGVQKNLNRASDALGTSMSRLSSGLKINSAKDDAAGLQISNRLTSQISGLNVAVKNANDGISIAQTAEGAMQASTNILQRMRELALQSANGSNSDEDRTSLQQEFTALSGELTRISSTTTFGGRNLLDGTFTSTSFQVGANANETISFGMKSVSASELKGNYNEASVDAGTNKLSAVVTGKADVISSNANVVSGTKFDIENKTLGAAAVGTLTVGGQNIALVASDDLDSIVKKINDEGLADVVASKEDGKLKISNDSGTAVAIGGTAATVAALGLPTSVADADSETGSEQLGPQTVNTAGDLIIGSSVVKLAASDTLEDVVNKINNFSSETGVTAKIAKDANGLGSLSLSSKTDFTIGKSTTAAVATKFGFATTPTADVTVKTTTGLTSSASIKLNDQTFDFATGSTLSDIVSKINDGAGAPGMGEGTKATGVVASASADGRLILTSADGKDVKLENNSAGALNSLGLSSGNTKAKLTEDTSITVNNVEIKFKKDDDMSAIAASINSSSSGVTATVNKDGTLALAGDQDIEISDGSNGTGLAALGLSAGTTKAVKMDTSVNDLSILDAASAQQAIQALDGAIQQVDSQRSQLGAIQNRFDSTVDNLQSIAENSTAARSRVQDADFASETAELTKQQTLQQASTAILSQANQLPSSVLKLLG
>NC_015733.1|WP_013973047.1|4266930_4267914_+|IS5-like-element-IS2000-family-transposase
MSQMSFSDFEYAGKRKQTRRERFLAEMEQVVPWSGLVALIEPHYPKAGGGRKPYPLETMLRIHLLQNWFSLSDPAMEEALYEITSMRQFARLTLSAPIPEDTTIMNFRHLLEKHQLAAGILETINNYLQDKGLSLRQGTIVDATIIHAPSSTKNKEGKRDPEMHQTKKGNQYYFGMKAHIGADAESGLVHHVHGTAANVADVTEVAQLLHGEENVVCADAGYTGVEKRPEHEGRQVIWQVAARRSTYKHLSKRSVLYQAKRKIEKAKAQVRAKVEHPFRVIKRQFGYVKTRFRGLAKNTAQLTTLFALSNLWMVRRQLLPAAGEVRP
>NC_015733.1|WP_044047134.1|4268140_4269070_-|ketoacyl-ACP-synthase-III
MIGIKSIASYVPSAGLDNYVQGAKFGKDEEFMFGKIGASFLPRKAEEQETSDLCVEAAQALFASNPDLDPQSIDALIVVTQNGDEEGLPHTAAIVQSKLGLSTRVAAFDVSLGCSGYVYGLYAIKGFMEAAGLKNGLLITADPYSKIVDPEDRNTTMLFGDAATATWMGENAVWNLGEARFGTDGSGAEHLKVTDGKFFMNGRQVFNFALVKVPAHLHELLDASGLKSSDIDAFCIHQGSAAIVDAVARRFEEQHPEKFVKDMLETGNTVSSSVPLLLQKHMLDGSWKRVAISGFGVGLSWGSAILYRD
>NC_015733.1|WP_013973616.1|4269491_4271057_-|flagellar-hook-associated-protein-3
MRISTAQFYETSATGYSQNYSNLAKITEQVTSKSRIQSAGDDPVGAARLLVLQQQSALLDQYSGNMTTVKNALLQEESVLSTINDALQRASELAIQAGNGGLSDADRTSIASEIKEIEANVFGLLNSRDANGDYMFGGSKSSTPPYVRNADGTYSYQGDQTQLSLQVSDTLRLATNDTGYSIFDQATNNSRTQSNLVAPSPDDGKVLLSGGLLTSATTYSNQFAAGQPYTVTFTSATEYSVKDAAGNDITNETAGKGKFDVNTEGGKMISLRGVDFEINLNLAEGDDADAVVAGHVFTLEAKPDTLTATRSAGNPSTAQVTGSSVTDPEAYRSTFPSNGAVIRFTSDTEYSLYAQPYSADSKPIATGTVGAGNAVTVAGVTYQFDSTPAQGDQFSVNANTHRTQNVLDTLGQLRSALEKPLDSPEAQAALKAATDSAISNLASARDRIDITRGSIGARGNSLDIQAQENESLGLANKSTQSAIGDTDMASATIQLTLQQAMLEASQLAFARISQLSLFDKI
>NC_015733.1|WP_013973617.1|4271070_4273113_-|flagellar-hook-associated-protein-FlgK
MSSLISIGLSGLSASQAALSVTSNNIANAATSGYSRQQTIQAAGPSHNIGAGFLGTGTTLSDVRRIYSAYLDNQLQTATSLQADSVAFQDQITSVDKLLADRDTGISSVLTAFFSALQTASAKPGDVASRQLLLTQAQTLSNRFNAVSTQLNQQNEVINSQLDTLAGQVNKLTGSIAEYNKQIAAASATGNTPNSLLDARSEAVRQLNELVGVTVQERDGNYDVYLGSGQSLVTGNKANTLSVQPGTADKSQASLRINYESFSSDVTSVITGGTIGGLLRYRQDVLTPSMNELGRVALVVADSINSQLGQGLDANGQFGSSLFSSINSATAVAQRSLASSNNSAGSGNLNVTIADSGALSTYDYEVKFTSANQYSVRRSDGTDMGTFDLSADPAPVIDGFTLSLNGGGLAAGDSFKVIPTRSAAGSITTTLTDANKLAFAGPISATAGSGNSGTGTITQPTLGESLNIYGGADTALVQQAIRDSMPVRVVFDAASGGSQGYKLYDAKGTQIGTGSVVPGQDNKLSIAVPMRDASGNPILDGSGNPRTFAVETTIGGSPATNDSFTLSFNADGKADNRNANALLDLQTKSTVGTNSGTGTSFTSAYASLVERVGAKASQAAIDTTATQAVFKSAAESRSAVSGVNLDDEAASLVKFQHYYTASSQIIKAAQETFSTLINAL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

282628 : 344853

Bacillus_phage(28.57%)

holin,bacteriocin,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_169774668.1\|282628_283078_-\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_013970457.1\|283220_283622_+	RNA-binding protein S4	NA	NA	NA	NA
WP_023662013.1\|283751_284546_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_013970459.1\|284667_285567_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_013970460.1\|285746_287288_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	6.6e-126	46.9
WP_013970461.1\|287502_287943_+	thioesterase family protein	NA	NA	NA	NA
WP_013970462.1\|287998_288481_-	hypothetical protein	NA	NA	NA	NA
WP_024087994.1\|288798_291144_-	FdhF/YdeP family oxidoreductase	NA	NA	NA	NA
WP_013970464.1\|291149_291980_-	formate dehydrogenase accessory sulfurtransferase FdhD	NA	NA	NA	NA
WP_013970465.1\|292165_292606_+	peptidoglycan-binding protein LysM	NA	NA	NA	NA
WP_003257447.1\|292717_293380_-	GMP/IMP nucleotidase	NA	NA	NA	NA
WP_013970466.1\|293444_294011_+	ADP compounds hydrolase NudE	NA	NA	NA	NA
WP_013970467.1\|294007_294826_+	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_013970468.1\|294997_295453_-	YiiD C-terminal domain-containing protein	NA	NA	NA	NA
WP_013970469.1\|295452_296859_-	sigma-54-dependent Fis family transcriptional regulator	W8CYM9	Bacillus_phage	3.9e-08	28.7
WP_024087997.1\|296855_298670_-	sensor histidine kinase	NA	NA	NA	NA
WP_013970471.1\|298712_299258_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	4.6e-50	53.9
WP_013970472.1\|299537_300644_+	agmatine deiminase	M1I1E2	Acanthocystis_turfacea_Chlorella_virus	4.3e-103	50.6
WP_013970473.1\|301158_303237_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_013970474.1\|303742_305062_+	OprD family porin	NA	NA	NA	NA
WP_013970475.1\|305179_306847_-	FMN-binding glutamate synthase family protein	NA	NA	NA	NA
WP_013970476.1\|306962_308351_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_023661060.1\|308352_309072_-	response regulator	W8CYM9	Bacillus_phage	1.1e-30	34.1
WP_013970478.1\|309212_311510_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_013970481.1\|313416_313623_-	DUF3079 domain-containing protein	NA	NA	NA	NA
WP_003257464.1\|313949_314198_-	hypothetical protein	NA	NA	NA	NA
WP_013970482.1\|314761_315037_+	DUF3077 domain-containing protein	NA	NA	NA	NA
WP_013970483.1\|315360_316596_-	methyltransferase	NA	NA	NA	NA
WP_013970484.1\|316720_317410_-	ABC transporter permease	NA	NA	NA	NA
WP_013970485.1\|317409_318102_-	ABC transporter permease	NA	NA	NA	NA
WP_013970486.1\|318156_318909_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003257472.1\|318920_319694_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.4e-21	32.0
WP_013970487.1\|320359_321745_+	GABA permease	NA	NA	NA	NA
WP_013970488.1\|321926_322370_-	hypothetical protein	NA	NA	NA	NA
WP_162097111.1\|322427_323300_-	polyphosphate kinase 2	NA	NA	NA	NA
WP_003257478.1\|323781_324054_-	oxidative damage protection protein	NA	NA	NA	NA
WP_013970490.1\|324050_325118_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_023661917.1\|325114_327361_-	AsmA family protein	NA	NA	NA	NA
WP_013970492.1\|327666_329328_+	OFA family MFS transporter	NA	NA	NA	NA
WP_003255736.1\|329566_330160_+	imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_013970493.1\|330160_330799_+	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_013970494.1\|330799_331060_+	DUF2164 domain-containing protein	NA	NA	NA	NA
WP_003257484.1\|331087_331825_+	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_013970495.1\|331835_332606_+	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_003257485.1\|332723_333902_-\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.9e-24	36.2
WP_169774667.1\|333898_334747_-\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_003257486.1\|334828_335776_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013970497.1\|336229_337606_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_015268639.1\|338063_339170_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_003257487.1\|339289_339547_-	hypothetical protein	NA	NA	NA	NA
WP_013970499.1\|339967_340444_-	thioesterase family protein	NA	NA	NA	NA
WP_013970500.1\|340454_341420_-	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_024088001.1\|341438_342323_-	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_013970502.1\|342444_343389_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_024088002.1\|343536_344481_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_038408553.1\|344601_344853_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

DBSCAN-SWA_2

1094919 : 1102698

Thermobifida_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013971076.1\|1094919_1095774_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	6.2e-09	32.8
WP_015269060.1\|1095776_1096241_-	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_003255135.1\|1096253_1096562_-	ribosome-associated translation inhibitor RaiA	A0A0K1LP60	Escherichia_phage	4.4e-05	34.1
WP_044046900.1\|1096641_1098135_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_003257916.1\|1098310_1099036_-	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.9e-23	27.0
WP_023660773.1\|1099036_1099561_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_013971080.1\|1099547_1100120_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_013971081.1\|1100128_1100653_-	HAD family hydrolase	A0A140XBD6	Dickeya_phage	1.2e-26	47.4
WP_013971082.1\|1100665_1101640_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	1.0e-36	32.8
WP_012270662.1\|1101888_1102698_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.5e-25	32.5

DBSCAN-SWA_3

1345722 : 1425802

Pseudomonas_phage(40.0%)

plate,tail,integrase,holin,terminase,capsid,protease,portal,tRNA,head

attL 1352430:1352463|attR 1422219:1422252

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013971264.1\|1345722_1347006_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_004375437.1\|1347275_1348904_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.2e-157	52.9
WP_013971265.1\|1348907_1349753_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.1e-50	42.0
WP_013971266.1\|1349906_1351196_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	7.4e-139	59.4
WP_004375443.1\|1351363_1351645_+	cell division protein FtsB	NA	NA	NA	NA
WP_013971268.1\|1351641_1352349_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
1352430:1352463	attL	NA	NA	NA	NA
WP_013971269.1\|1352481_1353378_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013971270.1\|1353485_1354598_+	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	8.0e-33	29.5
WP_013971271.1\|1354606_1355461_+	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_013971272.1\|1355637_1356111_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_013971273.1\|1356107_1357166_+\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_013971274.1\|1357153_1357903_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	4.4e-67	52.2
WP_015269209.1\|1357938_1358577_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.7e-40	51.2
WP_023662488.1\|1358794_1359652_+	peptidoglycan DD-metalloendopeptidase family protein	I3PV79	Clostridium_phage	1.9e-13	36.2
WP_013971277.1\|1359760_1360768_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	5.0e-34	35.8
WP_004375459.1\|1361384_1361708_-	ferredoxin family protein	NA	NA	NA	NA
WP_038408954.1\|1361848_1364422_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	7.6e-26	22.7
WP_038408956.1\|1364472_1365450_-\|integrase	tyrosine-type recombinase/integrase	A0A1B0VP19	Pseudomonas_phage	1.1e-131	70.8
WP_013971280.1\|1365462_1365657_-	DUF4224 domain-containing protein	A0A2H4JC20	uncultured_Caudovirales_phage	5.7e-19	67.7
WP_013971281.1\|1365695_1366055_-	hypothetical protein	NA	NA	NA	NA
WP_038408963.1\|1366231_1366420_-	hypothetical protein	NA	NA	NA	NA
WP_038408967.1\|1366416_1366812_-	DUF2591 family protein	A0A1B0VMD7	Pseudomonas_phage	1.1e-13	37.6
WP_013971283.1\|1366808_1367321_-	hypothetical protein	A0A1B0VM38	Pseudomonas_phage	1.2e-07	57.1
WP_038408969.1\|1367317_1367671_-	DUF4884 domain-containing protein	A0A2H4J399	uncultured_Caudovirales_phage	2.7e-11	45.3
WP_144241749.1\|1367667_1368018_-	hypothetical protein	A0A023NGB2	Nitrincola_phage	9.0e-23	50.0
WP_038408974.1\|1368527_1368752_-	hypothetical protein	NA	NA	NA	NA
WP_013971286.1\|1368748_1369411_-	hypothetical protein	NA	NA	NA	NA
WP_038408976.1\|1369473_1370136_+	hypothetical protein	NA	NA	NA	NA
WP_038408978.1\|1370157_1371033_-	hypothetical protein	A0A2H4J418	uncultured_Caudovirales_phage	1.2e-95	55.9
WP_038408980.1\|1371166_1371556_+	hypothetical protein	NA	NA	NA	NA
WP_013971288.1\|1371639_1372401_-	hypothetical protein	A0A2H4J7T1	uncultured_Caudovirales_phage	1.5e-123	85.8
WP_013971289.1\|1372513_1372894_+	hypothetical protein	NA	NA	NA	NA
WP_013971290.1\|1372964_1373423_-	hypothetical protein	A0A2H4J101	uncultured_Caudovirales_phage	3.1e-47	61.8
WP_038408982.1\|1373419_1373689_-	hypothetical protein	NA	NA	NA	NA
WP_013971292.1\|1373707_1374091_-	helix-turn-helix transcriptional regulator	A0A2H4JA92	uncultured_Caudovirales_phage	9.5e-26	59.8
WP_013971293.1\|1374482_1374923_-	tellurite resistance protein	A0A2H4P7E3	Pseudomonas_phage	1.8e-28	48.3
WP_049798432.1\|1375265_1375544_-	DUF1654 domain-containing protein	NA	NA	NA	NA
WP_080563747.1\|1375659_1376391_-	LexA family transcriptional regulator	K7P850	Enterobacteria_phage	6.9e-49	49.5
WP_080563748.1\|1376421_1376652_+	helix-turn-helix domain-containing protein	W6MWX8	Pseudomonas_phage	7.7e-07	49.2
WP_080563749.1\|1376788_1377646_+	replication protein	B5WZX9	Pseudomonas_phage	5.4e-37	37.7
WP_038408984.1\|1377635_1378448_+	ATP-binding protein	A0A2H4J3E5	uncultured_Caudovirales_phage	6.8e-98	67.5
WP_013971297.1\|1378450_1378747_+	DUF1364 domain-containing protein	A0A220NQY2	Salmonella_phage	2.6e-31	69.9
WP_013971298.1\|1378743_1379172_+	VRR-NUC domain-containing protein	A0A2D1GNH3	Pseudomonas_phage	4.0e-49	75.7
WP_038408986.1\|1379168_1380467_+\|integrase	site-specific integrase	A0A2D1GND4	Pseudomonas_phage	9.8e-131	57.2
WP_144241750.1\|1380463_1380748_+	hypothetical protein	NA	NA	NA	NA
WP_038410364.1\|1380744_1381062_+	hypothetical protein	A0A2D1GNG3	Pseudomonas_phage	2.6e-29	59.0
WP_038408988.1\|1381074_1381746_+	hypothetical protein	J7HXH6	Pseudomonas_phage	1.5e-58	53.5
WP_013971302.1\|1382059_1382383_+\|holin	phage holin, lambda family	A0A1W6JTC7	Pseudomonas_phage	1.7e-28	63.2
WP_013971303.1\|1382386_1382707_+	HNH endonuclease	B5WZZ4	Pseudomonas_phage	1.7e-28	59.8
WP_038408990.1\|1382841_1383309_+\|terminase	phage terminase small subunit P27 family	Q9B019	Phage_GMSE-1	5.5e-44	59.7
WP_049798433.1\|1383268_1385077_+\|terminase	terminase large subunit	A0A0U2C138	Paracoccus_phage	9.5e-116	41.3
WP_010954706.1\|1385073_1385262_+	hypothetical protein	Q8W6U8	Burkholderia_virus	1.3e-07	63.5
WP_013971306.1\|1385264_1386536_+\|portal	phage portal protein	A4JWZ9	Burkholderia_virus	1.1e-150	63.9
WP_013971307.1\|1386532_1387504_+	S49 family peptidase	A4JX00	Burkholderia_virus	1.5e-91	55.3
WP_038408992.1\|1387565_1388879_+\|capsid	phage major capsid protein	A4JX01	Burkholderia_virus	1.3e-146	61.2
WP_049798434.1\|1388853_1389180_+	hypothetical protein	NA	NA	NA	NA
WP_038408995.1\|1389182_1389734_+	hypothetical protein	NA	NA	NA	NA
WP_013971311.1\|1389736_1390111_+\|head,tail	head-tail adaptor protein	U5P0R0	Shigella_phage	6.7e-16	35.7
WP_038408997.1\|1390103_1390607_+	hypothetical protein	M1FPE2	Enterobacteria_phage	2.8e-09	32.2
WP_013971313.1\|1390637_1391231_+	hypothetical protein	B5TK65	Pseudomonas_phage	5.4e-52	51.5
WP_013971314.1\|1391236_1391440_+	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	2.2e-05	60.0
WP_013971315.1\|1391439_1392927_+\|tail	phage tail sheath subtilisin-like domain-containing protein	B5TK67	Pseudomonas_phage	2.2e-163	59.3
WP_013971316.1\|1392980_1393328_+\|tail	phage tail tube protein	B5TK68	Pseudomonas_phage	2.8e-32	54.8
WP_013971317.1\|1393324_1393621_+\|tail	phage tail assembly protein	B5TK69	Pseudomonas_phage	1.2e-28	71.0
WP_013971318.1\|1393750_1395706_+\|tail	phage tail tape measure protein	Q8W620	Enterobacteria_phage	1.3e-115	50.8
WP_013971319.1\|1395698_1396961_+	DNA circularization N-terminal domain-containing protein	B5TK71	Pseudomonas_phage	4.5e-64	37.6
WP_013971320.1\|1396964_1398074_+	hypothetical protein	B5TK72	Pseudomonas_phage	3.3e-103	56.2
WP_013971321.1\|1398082_1398583_+\|plate	phage baseplate assembly protein	B5TK73	Pseudomonas_phage	8.3e-54	67.3
WP_013971322.1\|1398579_1398966_+	phage GP46 family protein	B5TK74	Pseudomonas_phage	5.6e-26	51.6
WP_038409005.1\|1398955_1399999_+\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	3.7e-72	43.4
WP_013971324.1\|1399989_1400634_+	YmfQ family protein	NA	NA	NA	NA
WP_013971325.1\|1400636_1401404_+	hypothetical protein	A0A2H4J9C3	uncultured_Caudovirales_phage	2.6e-22	53.5
WP_038409008.1\|1401406_1401598_+	hypothetical protein	NA	NA	NA	NA
WP_013971327.1\|1404036_1404765_+	hypothetical protein	NA	NA	NA	NA
WP_013971328.1\|1404816_1406025_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_038409010.1\|1406152_1406692_+	glycoside hydrolase family 104 protein	Q9MC90	Pseudomonas_phage	7.6e-45	58.6
WP_013971330.1\|1406688_1407054_+	hypothetical protein	H2BDA0	Pseudomonas_phage	1.9e-15	44.1
WP_144241808.1\|1407062_1407326_+	hypothetical protein	H2BDD7	Pseudomonas_virus	2.0e-19	60.0
WP_013971332.1\|1407425_1407872_+	hypothetical protein	NA	NA	NA	NA
WP_013971333.1\|1407968_1410209_-	calcium-binding protein	NA	NA	NA	NA
WP_038409012.1\|1410829_1412581_+	type I secretion system permease/ATPase	G3M9Y6	Bacillus_virus	4.0e-10	28.4
WP_038410367.1\|1412777_1413002_+	hypothetical protein	A0A2H4JG60	uncultured_Caudovirales_phage	7.7e-28	83.8
WP_038409014.1\|1413075_1413369_+	hypothetical protein	A0A2H4JER5	uncultured_Caudovirales_phage	1.0e-35	72.2
WP_038409016.1\|1413365_1413659_+	hypothetical protein	NA	NA	NA	NA
WP_013971338.1\|1414101_1414584_+	CinA family protein	B5TK85	Pseudomonas_phage	2.8e-59	78.0
WP_013971339.1\|1414687_1415755_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	6.4e-112	62.0
WP_015269215.1\|1415776_1416247_+	recombination regulator RecX	NA	NA	NA	NA
WP_013971341.1\|1416296_1417415_-	LOG family protein	NA	NA	NA	NA
WP_013971342.1\|1417577_1417787_+	hypothetical protein	NA	NA	NA	NA
WP_013971343.1\|1417800_1418220_-	quorum-sensing-regulated virulence factor family protein	NA	NA	NA	NA
WP_013971344.1\|1418441_1419152_+	DTW domain-containing protein	NA	NA	NA	NA
WP_013971345.1\|1419230_1419881_+	response regulator transcription factor	NA	NA	NA	NA
WP_004375479.1\|1419954_1420320_+	diacylglycerol kinase	NA	NA	NA	NA
WP_004375481.1\|1420316_1421243_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004375483.1\|1421364_1422144_+	ferredoxin--NADP reductase	NA	NA	NA	NA
WP_013971347.1\|1423488_1423983_-\|protease	SprT family zinc-dependent metalloprotease	NA	NA	NA	NA
1422219:1422252	attR	NA	NA	NA	NA
WP_003252385.1\|1424115_1424715_-	YIP1 family protein	NA	NA	NA	NA
WP_012270926.1\|1424977_1425802_+\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	1.5e-105	71.6

DBSCAN-SWA_4

1918136 : 2012268

uncultured_Caudovirales_phage(61.9%)

plate,tail,integrase,holin,terminase,transposase,capsid,protease,portal,tRNA,head

attL 1943322:1943355|attR 2017495:2017528

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013970314.1\|1918136_1919090_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_013971722.1\|1919199_1922508_-	DEAD/DEAH box helicase	V9XTV7	Choristoneura_murinana_nucleopolyhedrovirus	2.0e-50	31.4
WP_013971723.1\|1922512_1923085_-	peptidoglycan binding protein CsiV	NA	NA	NA	NA
WP_031324543.1\|1926712_1928176_+	glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_044046931.1\|1928371_1929370_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_013971726.1\|1929572_1930967_+	Si-specific NAD(P)(+) transhydrogenase	NA	NA	NA	NA
WP_013971727.1\|1931009_1931732_-	glycerophosphodiester phosphodiesterase	NA	NA	NA	NA
WP_013971728.1\|1931763_1932348_-	PilZ domain-containing protein	NA	NA	NA	NA
WP_044046932.1\|1932431_1933682_+	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_169774647.1\|1933689_1934373_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	2.4e-40	42.5
WP_013971731.1\|1934434_1935676_+	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_044046933.1\|1935810_1937163_-	heavy metal sensor histidine kinase	NA	NA	NA	NA
WP_013971734.1\|1937159_1937840_-	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	1.5e-26	34.7
WP_013971735.1\|1938047_1938878_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	A0A126HHM5	Vibrio_phage	1.0e-32	36.0
WP_004376395.1\|1939003_1939267_-	DUF4404 family protein	NA	NA	NA	NA
WP_013971737.1\|1939389_1939953_-	hypothetical protein	NA	NA	NA	NA
WP_015269550.1\|1940152_1940860_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_013971739.1\|1940999_1941299_-	PilZ domain-containing protein	NA	NA	NA	NA
WP_015269551.1\|1941580_1942765_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_013971741.1\|1942761_1943244_+	STAS domain-containing protein	NA	NA	NA	NA
1943322:1943355	attL	NA	NA	NA	NA
WP_044046934.1\|1943384_1945235_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_013971743.1\|1945441_1946368_-	transaldolase	A0A1D7SEQ4	Cyanophage	8.5e-12	30.0
WP_044046935.1\|1946713_1947724_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_013971745.1\|1947825_1948947_+\|integrase	site-specific integrase	L7TP61	Pseudomonas_virus	1.1e-130	60.6
WP_148265635.1\|1949193_1950282_+	hypothetical protein	NA	NA	NA	NA
WP_013971746.1\|1950271_1950598_+	STAS-like domain-containing protein	A0A2H4J4X6	uncultured_Caudovirales_phage	7.9e-05	29.8
WP_044046936.1\|1950614_1951124_+	hypothetical protein	NA	NA	NA	NA
WP_013971747.1\|1951869_1952133_-	pyocin activator PrtN family protein	A0A2K8HN48	Pseudomonas_phage	1.7e-21	59.8
WP_044046938.1\|1952509_1953007_-	hypothetical protein	NA	NA	NA	NA
WP_044046939.1\|1953092_1953341_-	pyocin activator PrtN family protein	A0A2H4J8B4	uncultured_Caudovirales_phage	7.5e-16	55.8
WP_148265675.1\|1953337_1953814_-	hypothetical protein	NA	NA	NA	NA
WP_013971752.1\|1954151_1954856_-	hypothetical protein	A0A0U4JEE2	Pseudomonas_phage	9.9e-37	41.0
WP_016485750.1\|1954953_1955178_+	helix-turn-helix domain-containing protein	A0A0R6PIJ0	Moraxella_phage	5.6e-10	39.7
WP_042914267.1\|1955307_1955796_+	hypothetical protein	A0A2H4JFM0	uncultured_Caudovirales_phage	2.5e-31	54.7
WP_013971754.1\|1955788_1955992_+	TraR/DksA C4-type zinc finger protein	A0A2H4JDJ0	uncultured_Caudovirales_phage	4.3e-17	63.2
WP_013971755.1\|1959016_1959556_+	hypothetical protein	NA	NA	NA	NA
WP_044046940.1\|1959762_1960110_+\|holin	holin	A0A2H4J893	uncultured_Caudovirales_phage	1.1e-41	75.5
WP_044046941.1\|1960125_1960374_-	hypothetical protein	A0A2H4J888	uncultured_Caudovirales_phage	1.4e-14	53.7
WP_044046942.1\|1960491_1960836_+	hypothetical protein	A0A2H4JBW4	uncultured_Caudovirales_phage	1.0e-18	51.4
WP_013971757.1\|1961002_1961584_+	hypothetical protein	A0A2H4JG15	uncultured_Caudovirales_phage	2.9e-58	62.2
WP_044046943.1\|1961588_1963628_+\|terminase	phage terminase large subunit family protein	A0A2H4J898	uncultured_Caudovirales_phage	8.3e-302	79.7
WP_013971759.1\|1963629_1963836_+	hypothetical protein	A0A2H4JA19	uncultured_Caudovirales_phage	1.1e-17	67.6
WP_044046944.1\|1963832_1965314_+\|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	1.1e-215	74.1
WP_013971761.1\|1965310_1966462_+\|protease	Clp protease ClpP	A0A2H4JDI2	uncultured_Caudovirales_phage	1.9e-125	63.9
WP_013971762.1\|1966458_1966806_+\|head	head decoration protein	A0A2H4JF15	uncultured_Caudovirales_phage	1.5e-38	73.5
WP_013971763.1\|1966867_1967863_+\|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	5.9e-144	72.2
WP_013971764.1\|1967865_1968180_+	hypothetical protein	A0A2H4J879	uncultured_Caudovirales_phage	3.7e-28	58.7
WP_013971765.1\|1968176_1968839_+	hypothetical protein	A0A2H4JBV1	uncultured_Caudovirales_phage	5.6e-74	63.9
WP_013971766.1\|1968831_1969362_+	hypothetical protein	A0A2H4J881	uncultured_Caudovirales_phage	1.9e-32	47.2
WP_013971767.1\|1969358_1969961_+\|plate	phage baseplate assembly protein V	A0A2H4JG06	uncultured_Caudovirales_phage	7.9e-51	65.7
WP_013971768.1\|1970003_1970273_+	hypothetical protein	NA	NA	NA	NA
WP_013971769.1\|1970275_1970602_+	GPW/gp25 family protein	A0A2H4JA09	uncultured_Caudovirales_phage	2.8e-34	65.7
WP_013971770.1\|1970598_1971579_+\|plate	baseplate J/gp47 family protein	Q37840	Escherichia_phage	8.6e-47	38.9
WP_013971771.1\|1971575_1972388_+\|tail	phage tail protein I	V5YTN0	Pseudomonas_phage	7.0e-18	37.3
WP_044046945.1\|1972384_1973263_+\|tail	phage tail protein	A2I2X8	Vibrio_virus	2.3e-19	37.8
WP_013971773.1\|1973269_1974010_+	hypothetical protein	NA	NA	NA	NA
WP_013971774.1\|1974032_1974494_+	hypothetical protein	A0A077K9S5	Ralstonia_phage	2.3e-18	46.7
WP_013971775.1\|1974588_1975755_+\|tail	phage tail sheath family protein	A0A2H4J869	uncultured_Caudovirales_phage	3.0e-187	85.2
WP_013971776.1\|1975767_1976277_+\|tail	phage major tail tube protein	Q7M2A5	Pseudomonas_phage	3.4e-63	68.5
WP_013971777.1\|1976322_1976619_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_013971778.1\|1976751_1980240_+\|tail	phage tail tape measure protein	A0A2H4JG00	uncultured_Caudovirales_phage	2.3e-70	34.1
WP_013971779.1\|1980249_1981095_+\|tail	phage tail protein	A0A2H4J875	uncultured_Caudovirales_phage	3.7e-78	54.6
WP_010953963.1\|1981069_1981276_+\|tail	tail protein X	A0A2H4J9Z9	uncultured_Caudovirales_phage	2.5e-17	62.7
WP_013971781.1\|1981334_1982378_+	phage late control protein	A0A2H4JBF6	uncultured_Caudovirales_phage	5.6e-145	72.3
WP_013971782.1\|1982414_1982966_+	glycoside hydrolase family 19 protein	A0A2H4JHX4	uncultured_Caudovirales_phage	7.0e-62	66.5
WP_013971783.1\|1982962_1983523_+	hypothetical protein	A0A2H4JBH9	uncultured_Caudovirales_phage	2.3e-28	46.0
WP_044046946.1\|1983676_1984471_+	DNA adenine methylase	Q8W6S4	Burkholderia_virus	1.2e-99	66.5
WP_013971785.1\|1984503_1984779_-	hypothetical protein	NA	NA	NA	NA
WP_044046947.1\|1985439_1986384_+	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_044046948.1\|1986505_1986739_-	hypothetical protein	NA	NA	NA	NA
WP_044046949.1\|1986890_1987265_+	hypothetical protein	NA	NA	NA	NA
WP_013971786.1\|1987916_1989578_-	AIPR family protein	NA	NA	NA	NA
WP_024086588.1\|1990088_1990958_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_013971788.1\|1991364_1992402_+	sterol desaturase family protein	NA	NA	NA	NA
WP_044046951.1\|1992435_1993329_-	allantoinase PuuE	NA	NA	NA	NA
WP_013971790.1\|1993328_1994201_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_024086592.1\|1994384_1995302_-	amidohydrolase family protein	NA	NA	NA	NA
WP_013971792.1\|1995390_1996719_-	MFS transporter	NA	NA	NA	NA
WP_024086593.1\|1996797_1997775_-	hydroxyacid dehydrogenase	M1I636	Acanthocystis_turfacea_Chlorella_virus	8.9e-28	32.5
WP_013971794.1\|1998010_1998688_+	RraA family protein	NA	NA	NA	NA
WP_013971795.1\|1998820_2000002_+	MFS transporter	NA	NA	NA	NA
WP_013971796.1\|2000006_2001341_-	MFS transporter	NA	NA	NA	NA
WP_013971797.1\|2001387_2002308_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_024086594.1\|2002541_2003858_+	OprD family porin	NA	NA	NA	NA
WP_024086595.1\|2004106_2004823_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013971800.1\|2005357_2005840_+	formate dehydrogenase subunit gamma	NA	NA	NA	NA
WP_013971801.1\|2005833_2007411_+	formate dehydrogenase beta subunit	NA	NA	NA	NA
WP_013971802.1\|2007407_2010290_+	formate dehydrogenase subunit alpha	NA	NA	NA	NA
WP_013971803.1\|2010286_2010490_+	formate dehydrogenase subunit delta	NA	NA	NA	NA
WP_013971804.1\|2010632_2011496_-	universal stress protein	NA	NA	NA	NA
WP_013971805.1\|2011650_2012268_+\|tRNA	tRNA hydroxylase	NA	NA	NA	NA
2017495:2017528	attR	NA	NA	NA	NA

DBSCAN-SWA_5

2682907 : 2756438

Pseudomonas_phage(33.33%)

transposase,integrase

attL 2690768:2690783|attR 2755116:2755131

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085982910.1\|2682907_2684069_+\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.2e-82	52.9
WP_013972331.1\|2684204_2686148_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.8e-24	34.7
WP_044046998.1\|2687245_2688133_+	methylisocitrate lyase	NA	NA	NA	NA
WP_044046999.1\|2689487_2692082_+	Fe/S-dependent 2-methylisocitrate dehydratase AcnD	NA	NA	NA	NA
2690768:2690783	attL	NA	NA	NA	NA
WP_038410410.1\|2692215_2694816_+	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_013972336.1\|2695219_2695693_-	thioesterase family protein	NA	NA	NA	NA
WP_013972337.1\|2696154_2696889_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_049798444.1\|2696948_2697797_+	amidohydrolase	NA	NA	NA	NA
WP_049798445.1\|2697817_2698603_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_085982934.1\|2698612_2699608_+	oxidoreductase	NA	NA	NA	NA
WP_038409449.1\|2699621_2700959_+	phenylacetate--CoA ligase family protein	NA	NA	NA	NA
WP_013972341.1\|2701021_2702200_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_080563775.1\|2702295_2703381_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.2e-26	36.1
WP_123083716.1\|2703492_2704506_+	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_123083715.1\|2704505_2705777_+	ABC transporter permease	NA	NA	NA	NA
WP_044047000.1\|2705779_2706616_+	ABC transporter permease	NA	NA	NA	NA
WP_080563776.1\|2706748_2707636_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_085982917.1\|2708154_2709011_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.5e-18	40.5
WP_013972347.1\|2709252_2710173_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013972348.1\|2710274_2711621_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_038409454.1\|2711685_2713182_+	CoA-acylating methylmalonate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_038409455.1\|2713425_2714730_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_013972351.1\|2715007_2715637_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_038409457.1\|2715633_2716023_-	RidA family protein	NA	NA	NA	NA
WP_038409458.1\|2716081_2717389_-	OprD family porin	NA	NA	NA	NA
WP_044047001.1\|2717462_2718788_-	MHS family MFS transporter	NA	NA	NA	NA
WP_038409460.1\|2718927_2720154_-	Zn-dependent hydrolase	NA	NA	NA	NA
WP_038409461.1\|2720182_2721112_-	glyoxylate/hydroxypyruvate reductase A	M1HUW8	Acanthocystis_turfacea_Chlorella_virus	1.3e-07	31.3
WP_013972357.1\|2721108_2721864_-	class II aldolase/adducin family protein	NA	NA	NA	NA
WP_013972358.1\|2721877_2723173_-	MHS family MFS transporter	NA	NA	NA	NA
WP_013972359.1\|2723329_2724307_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_038409464.1\|2724356_2724590_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_013972360.1\|2724600_2726016_-	amino acid permease	NA	NA	NA	NA
WP_038409465.1\|2726360_2726783_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_013972362.1\|2726966_2728019_+	ornithine cyclodeaminase	A0A1V0SL93	Klosneuvirus	4.1e-95	52.3
WP_013972363.1\|2728051_2728990_+	hypothetical protein	NA	NA	NA	NA
WP_024086516.1\|2729688_2730669_-\|transposase	IS5-like element ISPa26 family transposase	A0A077K814	Ralstonia_phage	3.2e-94	56.7
WP_148265637.1\|2731627_2731819_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_044047250.1\|2732171_2733419_-\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A077KET4	Ralstonia_phage	1.0e-92	46.7
WP_013972366.1\|2733785_2735054_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	2.0e-40	31.3
WP_015270146.1\|2736328_2737351_+	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_013972369.1\|2737863_2739249_+	hypothetical protein	NA	NA	NA	NA
WP_013972370.1\|2739248_2740604_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_013972371.1\|2740792_2742103_-	MFS transporter	NA	NA	NA	NA
WP_013972372.1\|2742168_2743482_-	L-fuconate dehydratase	NA	NA	NA	NA
WP_193384130.1\|2743583_2743784_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_193384131.1\|2743802_2744531_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_013972373.1\|2744615_2745800_-\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	8.6e-126	59.6
WP_013972374.1\|2745969_2746146_-	hypothetical protein	A0A2H4J7S3	uncultured_Caudovirales_phage	7.2e-21	77.6
WP_013972375.1\|2746160_2746895_-	metallophosphoesterase	A0A2H4J0P0	uncultured_Caudovirales_phage	3.4e-141	91.8
WP_013972376.1\|2746946_2747408_-	hypothetical protein	B5WZU9	Pseudomonas_phage	3.0e-58	71.2
WP_013972377.1\|2747454_2747997_-	hypothetical protein	A0A1B0VP29	Pseudomonas_phage	3.0e-09	36.8
WP_080563778.1\|2748352_2748997_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_148265638.1\|2748993_2749428_+	hypothetical protein	NA	NA	NA	NA
WP_044047002.1\|2749541_2749736_-	hypothetical protein	NA	NA	NA	NA
WP_013972380.1\|2750077_2750623_-	hypothetical protein	J9Q748	Salmonella_phage	3.8e-20	35.6
WP_044047004.1\|2750738_2751239_+	hypothetical protein	NA	NA	NA	NA
WP_013972381.1\|2751180_2751735_-	hypothetical protein	A0A2H4JAQ1	uncultured_Caudovirales_phage	4.8e-10	57.1
WP_148265640.1\|2751843_2752533_+	hypothetical protein	NA	NA	NA	NA
WP_044047006.1\|2752770_2753277_-	hypothetical protein	A0A2H4J7C8	uncultured_Caudovirales_phage	1.4e-08	33.3
WP_013972383.1\|2753284_2753902_-	YqaJ viral recombinase family protein	A0A1B0VMB3	Pseudomonas_phage	8.5e-101	84.4
WP_013972384.1\|2753885_2754647_-	ERF family protein	A0A125RNR3	Pseudomonas_phage	2.4e-81	67.5
WP_044047007.1\|2754657_2755782_-	hypothetical protein	A0A1B0VN89	Pseudomonas_phage	2.8e-57	65.0
2755116:2755131	attR	NA	NA	NA	NA
WP_013972386.1\|2756070_2756247_-	hypothetical protein	NA	NA	NA	NA
WP_013972387.1\|2756243_2756438_-	hypothetical protein	A0A1B0VMB8	Pseudomonas_phage	9.4e-14	61.3

DBSCAN-SWA_6

2759456 : 2792069

Pseudomonas_phage(73.53%)

terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044047251.1\|2759456_2759774_+	DUF1654 domain-containing protein	A0A2K8HZW3	Pseudomonas_phage	6.0e-18	53.2
WP_013972390.1\|2759830_2760169_-	hypothetical protein	NA	NA	NA	NA
WP_009396425.1\|2760683_2760905_+	hypothetical protein	NA	NA	NA	NA
WP_009396426.1\|2761040_2761937_-	hypothetical protein	NA	NA	NA	NA
WP_013972392.1\|2761961_2762201_-	hypothetical protein	NA	NA	NA	NA
WP_013972393.1\|2762203_2763058_-	LexA family transcriptional regulator	A0A0S2SYF7	Pseudomonas_phage	1.9e-74	51.4
WP_013972394.1\|2763145_2763322_+	helix-turn-helix domain-containing protein	A0A0S2SYB8	Pseudomonas_phage	3.6e-12	64.4
WP_013972395.1\|2763387_2763576_+	hypothetical protein	B5WZX7	Pseudomonas_phage	7.0e-14	64.5
WP_044047010.1\|2763594_2763774_+	hypothetical protein	NA	NA	NA	NA
WP_044047011.1\|2764073_2764898_+	replication protein	W6MYB0	Pseudomonas_phage	5.8e-28	35.9
WP_013972397.1\|2764894_2766286_+	AAA family ATPase	A0A125RNK2	Pseudomonas_phage	6.1e-163	64.9
WP_013972398.1\|2766285_2766921_+	hypothetical protein	A0A0S2SYE7	Pseudomonas_phage	8.4e-19	33.3
WP_044047012.1\|2766988_2767210_+	hypothetical protein	NA	NA	NA	NA
WP_044047013.1\|2767209_2767512_+	hypothetical protein	A0A2H4JG78	uncultured_Caudovirales_phage	7.3e-05	45.8
WP_158308189.1\|2767508_2767682_+	hypothetical protein	NA	NA	NA	NA
WP_013972399.1\|2767678_2768260_+	ead/Ea22-like family protein	A0A2H4J8S0	uncultured_Caudovirales_phage	2.1e-16	70.0
WP_013972400.1\|2768252_2768723_+	hypothetical protein	A0A2H4J106	uncultured_Caudovirales_phage	4.5e-62	69.9
WP_044047014.1\|2768719_2769034_+	hypothetical protein	A0A2H4J249	uncultured_Caudovirales_phage	1.3e-12	43.6
WP_013972402.1\|2769024_2769627_+	recombination protein NinG	L7TH85	Pseudomonas_virus	1.9e-57	55.8
WP_193384132.1\|2769623_2769770_+	hypothetical protein	A0A2H4J3D6	uncultured_Caudovirales_phage	8.0e-18	95.7
WP_013972404.1\|2769766_2770456_+	hypothetical protein	Q9MC44	Pseudomonas_phage	1.2e-47	45.4
WP_044047015.1\|2770694_2771204_+	acyloxyacyl hydrolase	A0A2H4J0I5	uncultured_Caudovirales_phage	4.9e-86	97.0
WP_013972406.1\|2771378_2771690_+	hypothetical protein	A0A1B0VME9	Pseudomonas_phage	3.2e-16	50.5
WP_013972407.1\|2771689_2771959_+	hypothetical protein	A0A1B0VME7	Pseudomonas_phage	1.9e-17	57.6
WP_013972408.1\|2771995_2772232_-	hypothetical protein	NA	NA	NA	NA
WP_148265679.1\|2772312_2772507_+	hypothetical protein	NA	NA	NA	NA
WP_013972410.1\|2772515_2773139_+	hypothetical protein	A0A1B0VRJ1	Pseudomonas_phage	5.6e-84	69.6
WP_013972411.1\|2773170_2773647_+	DUF2280 domain-containing protein	A0A0S2SY97	Pseudomonas_phage	1.3e-53	80.0
WP_044047016.1\|2773618_2774917_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	7.9e-149	60.7
WP_044047017.1\|2774919_2776326_+	DUF4055 domain-containing protein	A0A0H5AWC7	Pseudomonas_phage	1.3e-173	64.6
WP_013972414.1\|2776325_2777402_+	hypothetical protein	A0A0H5BBX3	Pseudomonas_phage	7.6e-97	51.8
WP_013972415.1\|2777553_2778300_+	hypothetical protein	A0A0H5AWD1	Pseudomonas_phage	3.5e-93	77.2
WP_013972416.1\|2778309_2779278_+	hypothetical protein	A0A0H5ARK0	Pseudomonas_phage	1.4e-142	79.8
WP_013972417.1\|2779320_2779617_+	hypothetical protein	A0A0H5BBX8	Pseudomonas_phage	3.4e-07	55.0
WP_013972418.1\|2779616_2779988_+	hypothetical protein	A0A0S2SYB7	Pseudomonas_phage	2.3e-29	55.1
WP_013972419.1\|2779989_2780373_+	hypothetical protein	A0A059VA70	Pseudomonas_phage	1.1e-26	49.2
WP_013972420.1\|2780375_2780762_+	hypothetical protein	A0A059VF88	Pseudomonas_phage	1.0e-27	48.8
WP_013972421.1\|2780758_2781166_+	hypothetical protein	NA	NA	NA	NA
WP_042930044.1\|2781275_2781455_+	hypothetical protein	NA	NA	NA	NA
WP_042930042.1\|2781459_2781648_+	hypothetical protein	NA	NA	NA	NA
WP_013972422.1\|2781742_2782912_+	Ig domain-containing protein	A0A2I6PG25	Plesiomonas_phage	6.3e-12	24.8
WP_013972423.1\|2782969_2783455_+	hypothetical protein	NA	NA	NA	NA
WP_044047018.1\|2783562_2783799_+	hypothetical protein	NA	NA	NA	NA
WP_044047019.1\|2783854_2784184_+	superinfection immunity protein	A0A0S2SY85	Pseudomonas_phage	9.7e-11	50.8
WP_044047020.1\|2784240_2787150_+\|tail	phage tail length tape measure family protein	A0A0S2SYD9	Pseudomonas_phage	2.5e-78	30.4
WP_044047021.1\|2787146_2787458_+	hypothetical protein	NA	NA	NA	NA
WP_172402806.1\|2787532_2787679_+	hypothetical protein	NA	NA	NA	NA
WP_044047022.1\|2787705_2788158_+	hypothetical protein	NA	NA	NA	NA
WP_013972428.1\|2788154_2788634_+	DUF1833 family protein	J7I404	Pseudomonas_phage	8.2e-27	44.6
WP_044047023.1\|2788636_2789044_+	hypothetical protein	Q9MC96	Pseudomonas_phage	2.0e-18	38.2
WP_013972429.1\|2789009_2792069_+	hypothetical protein	B5WZT8	Pseudomonas_phage	8.2e-221	40.9

DBSCAN-SWA_7

3824106 : 3832800

uncultured_Caudovirales_phage(75.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003251184.1\|3824106_3824778_+	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	2.1e-105	91.0
WP_013973275.1\|3825012_3826392_+	uracil-xanthine permease	H9YQ34	environmental_Halophage	1.6e-27	51.1
WP_013973276.1\|3826576_3826969_+	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	9.3e-53	79.1
WP_024087386.1\|3826970_3827330_+	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	1.6e-35	63.3
WP_013973278.1\|3827329_3827626_+	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	3.5e-28	63.6
WP_013973279.1\|3827622_3827958_+	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	5.7e-43	76.6
WP_013973280.1\|3827954_3828959_+	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	8.3e-154	79.8
WP_013973281.1\|3829051_3830011_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_013973282.1\|3830127_3831519_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_003258877.1\|3831519_3832800_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.6e-96	54.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015733

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection