CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017186	Amycolatopsis mediterranei S699, complete sequence	27 crisprs	csa3,WYL,DEDDh,casR,cas4,cas6e,cas5,cas7,cse2gr11,cas8e,cas3,DinG	7	45	4	0

1. NC_017186

CRISPR-Cas detection and classification

Crispr_ID: NC_017186_1

• CRISPR_ID: NC_017186_1
• CRISPR_location: 70618-70717
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_1

Consensus_repeat	Method
ACTGCGGCTTTTCGGGGGCTCCGGGTGGCGGAGCCCC	CRISPRCasFinder

spacers of NC_017186_1

>1.1|70655|26|NC_017186|CRISPRCasFinder
CGGCTCGGGGCGAAGCCCTGGAGGTC

CRISPR arrays and Neighbor proteins around NC_017186_1

CRISPR arrays

The CRISPR arrays of NC_017186_1

>merge|NC_017186|1|70618-70717|CRISPRCasFinder
ACTGCGGCTTTTCGGGGGCTCCGGGTGGCGGAGCCCCCGGCTCGGGGCGAAGCCCTGGAGGTCACTGCGGCTTTTCGGGGGCTCCGGGTGGCGGAGCCCC

>NC_017186|1|1|70618-70717|CRISPRCasFinder
ACTGCGGCTTTTCGGGGGCTCCGGGTGGCGGAGCCCC	CGGCTCGGGGCGAAGCCCTGGAGGTC
ACTGCGGCTTTTCGGGGGCTCCGGGTGGCGGAGCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013222025.1|78495_79881_+|amidase	unknown	unknown	gnl|CDD|235915
NC_017186.1|WP_013222015.1|68991_69576_+|class-F-sortase	unknown	unknown	gnl|CDD|320678
NC_017186.1|WP_013222024.1|77730_78486_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|379263
NC_017186.1|WP_013222014.1|68209_68995_+|hypothetical-protein	unknown	unknown	gnl|CDD|237019
NC_017186.1|WP_013222011.1|63302_63677_-|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl|CDD|223619
NC_017186.1|WP_176742126.1|63818_67037_+|penicillin-acylase-family-protein	unknown	unknown	gnl|CDD|376618
NC_017186.1|WP_034284829.1|73080_74025_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223674
NC_017186.1|WP_013222009.1|61551_62283_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|214473
NC_017186.1|WP_013222022.1|75555_76329_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_017186.1|WP_014466497.1|69561_70602_-|patatin-like-phospholipase-family-protein	unknown	unknown	gnl|CDD|224666
NC_017186.1|WP_176742127.1|71593_73084_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|173859
NC_017186.1|WP_013222026.1|79953_81165_-|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NC_017186.1|WP_013222013.1|67095_68136_+|PLP-dependent-transferase	unknown	unknown	gnl|CDD|99738
NC_017186.1|WP_014466499.1|74024_74831_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_017186.1|WP_034284833.1|76321_77734_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143467
NC_017186.1|WP_013222021.1|74827_75559_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|223521
NC_017186.1|WP_013222010.1|62398_63151_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|214473
NC_017186.1|WP_013222008.1|59928_61164_-|DUF3662-and-FHA-domain-containing-protein	unknown	unknown	gnl|CDD|378850
NC_017186.1|WP_003079002.1|59366_59828_-|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|224630
NC_017186.1|WP_013222017.1|70722_71466_-|FadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225097

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013222025.1|78495_79881_+|amidase	gnl|CDD|235915	PRK07042, PRK07042, amidase; Provisional.	0
NC_017186.1|WP_013222015.1|68991_69576_+|class-F-sortase	gnl|CDD|320678	cd05829, Sortase_F, Sortase domain found in the class F family of sortases. Class F sortases are mainly present in Actinobacteria, Chlorobacteria and Firmicutes. Their functions are largely unknown.	2.56401e-56
NC_017186.1|WP_013222024.1|77730_78486_+|SDR-family-oxidoreductase	gnl|CDD|379263	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase.	3.50278e-60
NC_017186.1|WP_013222014.1|68209_68995_+|hypothetical-protein	gnl|CDD|237019	PRK11907, PRK11907, bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase.	0.000188145
NC_017186.1|WP_013222011.1|63302_63677_-|FKBP-type-peptidyl-prolyl-cis-trans-isomerase	gnl|CDD|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	4.19969e-41
NC_017186.1|WP_176742126.1|63818_67037_+|penicillin-acylase-family-protein	gnl|CDD|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	2.36873e-81
NC_017186.1|WP_034284829.1|73080_74025_+|ABC-transporter-permease	gnl|CDD|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.86039e-111
NC_017186.1|WP_013222009.1|61551_62283_-|trypsin-like-serine-protease	gnl|CDD|214473	smart00020, Tryp_SPc, Trypsin-like serine protease. Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.	6.81885e-22
NC_017186.1|WP_013222022.1|75555_76329_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	1.70598e-105
NC_017186.1|WP_014466497.1|69561_70602_-|patatin-like-phospholipase-family-protein	gnl|CDD|224666	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only].	9.36144e-12
NC_017186.1|WP_176742127.1|71593_73084_+|ABC-transporter-substrate-binding-protein	gnl|CDD|173859	cd08494, PBP2_NikA_DppA_OppA_like_6, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_017186.1|WP_013222026.1|79953_81165_-|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	8.55599e-62
NC_017186.1|WP_013222013.1|67095_68136_+|PLP-dependent-transferase	gnl|CDD|99738	cd00614, CGS_like, CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.	1.16449e-111
NC_017186.1|WP_014466499.1|74024_74831_+|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	4.6034e-86
NC_017186.1|WP_034284833.1|76321_77734_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143467	cd07149, ALDH_y4uC, Uncharacterized ALDH (y4uC) with similarity to Tortula ruralis aldehyde dehydrogenase ALDH21A1. Uncharacterized aldehyde dehydrogenase (ORF name y4uC) with sequence similarity to the moss Tortula ruralis aldehyde dehydrogenase ALDH21A1 (RNP123) believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and similar sequences are included in this CD.	1.16863e-178
NC_017186.1|WP_013222021.1|74827_75559_+|ABC-transporter-ATP-binding-protein	gnl|CDD|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.18868e-113
NC_017186.1|WP_013222010.1|62398_63151_-|trypsin-like-serine-protease	gnl|CDD|214473	smart00020, Tryp_SPc, Trypsin-like serine protease. Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.	8.27638e-20
NC_017186.1|WP_013222008.1|59928_61164_-|DUF3662-and-FHA-domain-containing-protein	gnl|CDD|378850	pfam12401, DUF3662, Protein of unknown function (DUF2662). This domain family is found in bacteria, and is approximately 120 amino acids in length. The family is found in association with pfam00498.	2.18895e-45
NC_017186.1|WP_003079002.1|59366_59828_-|FHA-domain-containing-protein	gnl|CDD|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	6.09676e-20
NC_017186.1|WP_013222017.1|70722_71466_-|FadR-family-transcriptional-regulator	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	3.27042e-44

Protein sequences

>NC_017186.1|WP_014466497.1|69561_70602_-|patatin-like-phospholipase-family-protein
MDAAKRNGVGLALSGGGYRAMLFHAGALWRLNELGWLPKLTTVSSVSGGSIAAGVLAHAWTKLWFGEDGVAENFGKEVVQPIRKLARTNLDVPVTLKAMMMPWRSAGEELARRYAKHLFGDCCLADLDPAGPHFVFTATSLQDGSLWWFFRQPGPHGQIPLATAVAASSAFPPMLSPVVIPDPHRAGHKIVLSDAGVYDNLGLDPIENQRATVLVSDAGKKMKHEDRPRHNWPMQLLRVLTVMDNQVRELRTGSLLKSYEDKTYAGTYWATYSDIEHFELPDALPAPVEQTRKLAETKTRLTRMSESTQDQLINWGYAVCDAGMRRWVCPGTGLKPEFPYPGSGVG
>NC_017186.1|WP_013222015.1|68991_69576_+|class-F-sortase
MTVRRAGAALALVLALAGCGTAEPPKAAAPAPAPASVPVTVPFKGLRPTSVKIPKIGAESSLLAVAVKPDGSISVPSVRTPMQAAWYKLSPVPGDVGPAIVLGHVDGDKKPGIFFKLKDLAPGDEVDIDRSDGRKLKFVVDRVTQVPKDTFPRDAVYGNSAKPELRLITCGGAFDHAEHSYKDNIVVYANLADA
>NC_017186.1|WP_013222014.1|68209_68995_+|hypothetical-protein
MSRFAGIVSAGALITFAAAPAALAQTTSETPTTPATTETTSETTTTAPPTSATTTPSTSVTTTGTTAPNPTREVTKTTTPGTTTSTSAESEPPKDDYQDNTGHGFVGLGGEGVLVIACAAGRPGEVATQYLSVTGGPDQDEADGRLWNYSVRVVDAPAGTTTAKFSWTCGGVEGNGTVEFEQEQPPTSTVTATSTPTSTSTSTTSSSAPASSTAPITTASITAVPSTTATSTTPAGNAAPKAQVKVAPKGGVETGFGGTAW
>NC_017186.1|WP_013222013.1|67095_68136_+|PLP-dependent-transferase
MDDWTPRTKAIAAGRPHGPGEPLNTPLVATSTYQAGGDFAYARGDGTPTWHALEEAVGALEGGHATAFASGVATLSAVLDLLPVGSRVAVPTFSYAVTRGVLAHAQKLGKLAVTELEPTDTEAWVAEAATSDLVWLESPTNPTLDVMAIEPIAAAARGRVVVDNTFATPLQQRPLELGADVVVHSATKLIGGHSDLLLGITVAKDPAVAAELRGARTRVGATPGALEAWLALRGLRTMPVRLAEQSRTAALLAERLAGHPAVRRVRYPGFGMMVSFDLADAETADRFCASVRLIRSATSLGGVESLVERRAWLAGEERVPAGLIRFSVGLEDPEDLWDDLAFALPE
>NC_017186.1|WP_176742126.1|63818_67037_+|penicillin-acylase-family-protein
MRRRIRALTVTALGALVAGLTQVAVTAPAAQAAVSPDDYCGGQCSDILPPGEQGSATLAEILAHKLLGTRPAHSADQLGKYSSLAGGYKTLTTSAINQYFNDSSFGVPADQVASTTKPRADVTIVRDKALGVPHITGTTRAGTEFGAGYAAGQDRLWLMDVLRHAARGQLSPFAGGAASNRELEQQFFSNAPYTEAELQAQIDRTAASGPRGAQGLADAQAYVDGINKYISDAYNGRYFPGEYVLTGHVDSITNAGSIDPFKLTDLVALASLVGAEFGAGGGGEVQNAIAKLAMQEKYGVVQGEKVWRSLRAEDDPEAVKTLHDGQTFPYGKTPANAAGQAMPDKNSVTPQPVVFDKTGSASTATPSTVDVAAPAEQEPARGIFENGVLPGNMLSEKHGMSNALLVSGAKTASGHPVAVFGPQTGYFAPQLLMLQELQGPGISARGAAFAGLSLYVLLGRGQDYSWSATTSAQDIIDTYALQLCDPSGNAPTKDSNYYTYQGKCVPMDTVEVKNAWKPTVADGTAAGSYTLRSYRTRYGPVQSRATVGGKPVAYTALRSSYFHEVDSLIGFQELNDPTFVKSAADFQRAAQDINFTFNWFYADSKDIAYFNSGANPVRPSDVDPNMPVWGDQGHDWVGWNPAGNVANYTPASQHPQSINQDYYVSWNNAQANGYAAAGADKSAVHRVDLLDSRVKKLIASGTKVTRVNLTQAMSEAALADLRAERVLPLLLQVLDKTPATGAAADAEAKLKTWLSHGQLRTETSPGSKAYADADAIRIFDAWWPLLVQAEFKPGMGDDAYNAMTGVLGINESPSGWQNGNGQHTGQPHKGSSFQFGWWGYVSKDIRQVLGQPVAGPLAQTFCGGGDVTACRQGLVDSLTTAAGQAANTVYPGDANCSAGDQWCADSIIQNPLGGITQDKISWQNRPTFQQVVEYAAHRGDNVANLAAAKTVSATSAETGFYDSPASNAIDGNASTRWASDWSDDQAITVDLGSVQQVSRVMLNWESAYGKSYRIQLSPDAVNWTDAAVVTDGDGGQDNLAFDATPARFVKLQGVQRGTKYGYSLYEFEVYAH
>NC_017186.1|WP_013222011.1|63302_63677_-|FKBP-type-peptidyl-prolyl-cis-trans-isomerase
MTLEKPLIDRPDGPPPAELEITDITVGDGAEATAGKSVTVHYVGVSHSTGEEFDASWNRGEPLRFGLGAGQVISGWDQGVAGMKIGGRRKLVIPPHLAYGDRGAGGVIKPGETLVFVVDLVGVN
>NC_017186.1|WP_013222010.1|62398_63151_-|trypsin-like-serine-protease
MRVRAVLSAALLTLAAGLATAPAASAVANGADVPAGQFGFAAKLTMTDIPKPNGTKYTSACSGALIAAQWIITAGHCFHDANRNRVSGPVPYPTSVLLGTVDQNAPGVTRNVVTVYQSSANDIAIATLDADVTGITPLTVNRVTPSAGQLLTLAGWGSLTSVNPAPSTKLQQGTVQVGQVGTATLGVLGVAPTSTTSACVYDSGAPYFVAGGDGGQLVSVESTGPDCPHHQLETTSRVDVVADWIASHTG
>NC_017186.1|WP_013222009.1|61551_62283_-|trypsin-like-serine-protease
MRLRALLAAAVLTVSTAPAAWAVAHGSDVPPGQYGFVAKLAMTKIPRPDGSTYSSFCTGALVAPDWVLTTGHCFHDAHRDRVSGKTPYPTTVTLGLTDEATESGIARKATEVLQAKENDVALVRLDSPVTTVTPLTVTRAAPKVGQQLTLAGWGSLTSSDPKPATRLQEGTVAVAKVDPTTLGVRGAAPEITTSACTYDSGAPYFSGNELVAVEATGPDCPHAGIETTSRADVIADWTATHTA
>NC_017186.1|WP_013222008.1|59928_61164_-|DUF3662-and-FHA-domain-containing-protein
MGRAERFDRRLENLVGNTFARMFGGNVVTQEVAIALERESEENVRELAGGRQLAPNHYIVSLGAADHERMAGDEQRVTQVLAKAVAEHLAAAGLDTYGDVVVSLERNEALHTGQFKTRSSVDPDARPSGAGSPRSARPSNAGDPAMSQPPGYGQYDQGDPYGQQGQYGYGQQGGQQPGYDQGYGQQGGYDQYGGQQPQGGGYDQYGQPQQGGGYDQYGQQPQAGYDQGYAQPQGGGYDQGGYQQPQGGGYDQGYGQPQGGGYDQGGYQQGGYDQYGQQQPQGGYDQYGQQQAYGQPAADPYAQQQGGYGQPAPGRQLAASLQLDDGSNRTYSLKQGGNVVGRGQDADFRLPDTGVSRRHLEITWDGQSATLADIGSTNGTTVNGTPVQTWQLADGDVIRVGHSSLVFRTQG
>NC_017186.1|WP_003079002.1|59366_59828_-|FHA-domain-containing-protein
MPELVVQLTRVGFLVLLWLFVFAALRVVRSDLYAASGMRVQVPTFGRKKEKKPRNSKSPQQLLVTHGALAGTRIALDGRPILIGRADDSTLVLDDDYASTRHARIAQRGEDWYVEDLGSTNGTYLDRAKVTAPLRVPLGVPIRIGKTVIELRP
>NC_017186.1|WP_013222017.1|70722_71466_-|FadR-family-transcriptional-regulator
MRFEPVAPVRAYERVVEQIEQAVVSGALKPGERLPSERELMTQFGVGRSTVREALRVLQAAEMIRSRPGDPRGPEVLAASPAALHRSMHRLARADHVGLAELLQFRMILDGSAHLLAAGLRTEEDLTGLDAALESMREGVSRGYAEFSRADVAFHEVIARISRNPLLVVSEEVVRGVVLELIEDKLEHASNRTSLMRTWLAHHAEVLDAIRAADGAGAAQLAKQALYDNYAEYVPAGQRPLLTPLLQ
>NC_017186.1|WP_176742127.1|71593_73084_+|ABC-transporter-substrate-binding-protein
MKARIPAVAAVLLLAVSGCSAGSSASVSAGPNTLSVGFTAEPANFDFTRTDGAAIPQALLYNVYEGLVRLDAQGRVVPLLAKSWTISPDRKTYDFQLQQGVKFSNGAPFTAEDVKFSLLRVKTDWTISIKANMDVIDHVDVEAPDHARVVLSKPSNGWLFSLTSRLGAMFSPTGIADLANKPVGTGPYVVAARKRGDSVVLKANPAYWGRKPAYGTVVLKYIKDPTALNNALFSNGIDVISAITAPDSIPQFQADDRFQVVQGTSNSEVTLAMNNARPPLNDVRVRQALTYAIDRKALLDTAWAGRGTLIGSMVPPTDPWYEDLANVHPFDPAKAKALLTEAHATNLNLRLRIPNLPYAVSAAQVVQSQLADVGVRTTIEPLDFPAVWLKQVFTDHDYDLSIIQHVEARDITTFGKPKYYWGYDSKRVQQLLAEADSGTPEQQVADMKQVARQLNTDAAADWLFLFPNVIVAKAKVGGFVQNQVSESFDLTGLAPR
>NC_017186.1|WP_034284829.1|73080_74025_+|ABC-transporter-permease
MTARVLRRVAIFVVSVLVASIVVFLFMAVLPGDPAQVALGVNATPELLAKTRAEFGIDRPLVTQYFDWIGGVLHGDFGRSYVTRDAIGPQLLDRLGVTLWLVGAGMLVALVIAIPAGTFAAVKHRKAAGASVSGLSQIGVAIPAFLAGIILVQIFAVQLRWLPSGGWTPPDQDAGEFLRGLILPALSLGLVQGAVLTRYVRSAVLDTLGQDYLRTARSKGLRPGQALVRHGLRNASVPVVTVLGLQLATLLIGAVVVERVFVLPGLGSMLLDAVSARDLLTVQGIVLVLVAGVLLVNFVVDLLYTVLDPRLRGS
>NC_017186.1|WP_014466499.1|74024_74831_+|ABC-transporter-permease
MRNLVIGGILVGLVVLAALLSFAWTPFDPVKVDAAHRLLGFTGSHWFGTDKFGRDLLSQLMVGARTTVYVGVVAVGIAAVIGTPLGILAGMSPRWLGEFVMRVNDLVLAFPALLLAIMFGAVFGADTLTAMVAIGIATIPSFARIARSGTLQVMSTEFVLAARAGGRSRLNIALRHVLPNISGLLIVQASVSFAIAVLAEAALSFLGFGTRPPTPSWGRMLQESQELLTVQPRLALVPGIAIAVAVLGFNLLGDGLRDRLDPRLAARL
>NC_017186.1|WP_013222021.1|74827_75559_+|ABC-transporter-ATP-binding-protein
MTLSVRGLSVSTLVRDVSFEIGAGERVGLIGESGSGKSLTALAIMGLLPEELPASGSVVLHDHELLEMSEKDLSRLRGDELAMVFQEPMTALNPAMRVGRQVTEPGRLRGRRHRAEDLLSAVGLPGTARAYPHQLSGGQRQRVVLAMALANEPSLLICDEPTTALDVTVQAQILSLIKTSLPAESALLFITHDLAVVASVCERVLVMLDGEIVEAGSTREVLTSPKHEYTRKLLDASDLEARR
>NC_017186.1|WP_013222022.1|75555_76329_+|ABC-transporter-ATP-binding-protein
MTVIEVRDLERRYARRDVHALRGVSFDVEAGQRFGIVGESGSGKSTLVRLLAALDKPTAGTVSFQGRRIDNLPERRLGFLRSELQIVFQDPMGSLDPRMRVRDIVSEPLGRREPDRVAELLAAVGLPADAAQRYPHQFSGGQRQRISIARALAPNPSVLIADEPVSALDVSVRGQILDLLGSLVEQFALTLVFVSHDLGVVRHVCDRVAVMRRGEIVELGDVPQVYDAPRHEYTRELLEAAPNLRAELARLRGGEDA
>NC_017186.1|WP_034284833.1|76321_77734_+|aldehyde-dehydrogenase-family-protein
MPEYPDGLPIGGGWVSTVDAEEIVFPYDGSVIGTAPVGTPELATRAVSEAVAIAREVASLPSRVRRSLLNDVAAAIRSRREEFENLLVLETGKPLVDCRVEVARTIVTWEAAAEEVSRLHGETVPLDLLPSGDGLVGFWKRKPIGVVVGIAGFNYPLLLASHKIAPAIAAGCPVIVKPAPQTPLATLWLVHLVRSVAPIAAMVQLVTGDAAVGAALTTDRRIGAVSFTGSAAVGHRIARDAAPTKTLLELGSNAALVVAPDADLDAAVDAVLRGGFYASGQACISVQRVLVVASVAEEFTERLVGRLDEVVVGDPRDEKTRVSALIDPASTARVAAWIEQAGARRVGGGVDGTVLRPTVLLDVPDGVEAWDEEIFGPVVCVRTVSDVDEAFAAVNASRYGLHASVYSRSLHTAFRALDELEVGGVVVNEVPGFRSDTMPYGGVKDSGIGREGPRFAVEELTVTRMAVLRP
>NC_017186.1|WP_013222024.1|77730_78486_+|SDR-family-oxidoreductase
MNYSTLFRLDGRRAVVLGAGGIGREAARALAAHGADVVCADRDLEAAREAGVGEPYEIDLLAPGAVDKAASDLGPLDVVVLTAATNVRKRLLDYTREEFDRVIALNLGVTFEVVRVFGADMVARGRGSIIGFSSIRGTTVEPGQGPYAATKAGLVQLFRTAAAEFGPAGVRVNAIAPGVVETPLTAQIKANPEWYAAYAAKGALGRWARPEELAGAVVYLASDASSFVTGSVLAVDGGWTAVDGRFDPPAS
>NC_017186.1|WP_013222025.1|78495_79881_+|amidase
MTELPDLTAVELVAQYRAKTLSPVEVTEAVLTRIEEREPELHALYAYDPSGARDDAKASEARWASNEPLGPIDGVPLTLKENIATRGTPVPLGTAATALVPAAEDAPAAARVRESGAVLLAKTTMPDYGMLTSGLSSFHTTARNPWQLSATPGGSSAGAGAAAAAGYGPLHVGTDIGGSIRLPAGWCGLTGLKPSFGRVPVDPPFLGRVAGPMTRTVADTTLLMSVLSRPDPRDHLCLPPSELDWSSTALPVGGLRVGLQLESGPGLPVDPAIRDAVTAAARAFEAAGAVVEPVEPFLTREMLDGLDVFWRTRAWSDLAALPRDRRAKVLPYIADWAAGGADASGVDVYRGFAQIDVMSVAALRATSAFDVVLSPVCPVAAPPAEWASPTNDPARPFEHIAFTVPYNMSGQPAVSLNCGYTDDGRPIGLQIAGRRFDDLGVLRVAAAYEGLRPPQRPWPIG
>NC_017186.1|WP_013222026.1|79953_81165_-|IS110-family-transposase
MKVRPLVWVGIDVGKAHHHACVMDPAGTVVFSQKVANDQAAIEQLVARAGQAAGEVRWAIDLTSNAAALLIAVLIASGQQVVYVPGRVVNRMTGVFRGEAKSDAKDARVIAETARMRTDLTPVTATDDLVIELTRLSAHREDLMADWVRGVNRLRDLLTGIFPALERAFDYSTRSALILITGFQTPQAIREAGETGVAGYLREHGAWAKGIPGMTADALAAAHAQTVQLPGEATTATLIAGLARQLLALDRQIKNTDKLLTSQFRQHPQAEIIESLPGLGPILGAEFLVVTGGNLTAFATPGRLASYAGLVPVPQDSGRVTGNLRRPKRYNRRLRRVFYMAALSSLKAGGPSRAFYDRKRSERLIHTQALLALARRLVDVLWALLRDSRTYTPTAPQPATAAA

Crispr_ID: NC_017186_2

• CRISPR_ID: NC_017186_2
• CRISPR_location: 301018-301110
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_2

Consensus_repeat	Method
GGCTTTCACGGGGGTCCGGGTGGCGGAGCCCC	CRISPRCasFinder

spacers of NC_017186_2

>2.1|301050|29|NC_017186|CRISPRCasFinder
CGGCGCGGGGCGGAGCCCCGGATGGCACG

CRISPR arrays and Neighbor proteins around NC_017186_2

CRISPR arrays

The CRISPR arrays of NC_017186_2

>merge|NC_017186|2|301018-301110|CRISPRCasFinder
GGCTTTCACGGGGGTCCGGGTGGCGGAGCCCCCGGCGCGGGGCGGAGCCCCGGATGGCACGGGCTTTCACGGGGGTCCGGGTGGCGCAGCCCC

>NC_017186|2|2|301018-301110|CRISPRCasFinder
GGCTTTCACGGGGGTCCGGGTGGCGGAGCCCC	CGGCGCGGGGCGGAGCCCCGGATGGCACG
GGCTTTCACGGGGGTCCGGGTGGCGCAGCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013222225.1|288419_290135_+|DUF2156-domain-containing-protein	unknown	unknown	gnl|CDD|235095
NC_017186.1|WP_013222227.1|292075_293704_+|cellulose-binding-domain-containing-protein	unknown	unknown	gnl|CDD|119365
NC_017186.1|WP_013222238.1|303325_303745_-|ATP-binding-protein	unknown	unknown	gnl|CDD|340413
NC_017186.1|WP_013222240.1|304583_305000_-|anti-sigma-factor	unknown	unknown	gnl|CDD|273879
NC_017186.1|WP_013222231.1|297541_298585_-|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NC_017186.1|WP_013222243.1|307164_307596_-|hypothetical-protein	unknown	unknown	gnl|CDD|226158
NC_017186.1|WP_013222230.1|296550_297468_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NC_017186.1|WP_003078104.1|305690_306044_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_017186.1|WP_013222241.1|305163_305472_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NC_017186.1|WP_013222226.1|290622_291867_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_034284974.1|306103_306892_+|metal-dependent-hydrolase	unknown	unknown	gnl|CDD|377294
NC_017186.1|WP_013222228.1|293700_295047_+|cellulose-binding-domain-containing-protein	unknown	unknown	gnl|CDD|119360
NC_017186.1|WP_013222234.1|300209_300953_+|3D-domain-containing-protein	unknown	unknown	gnl|CDD|270620
NC_017186.1|WP_013222236.1|301791_302769_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381312
NC_017186.1|WP_013222239.1|303807_304587_-|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274373
NC_017186.1|WP_013222232.1|298763_299435_+|HNH-endonuclease	unknown	unknown	gnl|CDD|377857
NC_017186.1|WP_013222235.1|301134_301773_-|nitroreductase-family-protein	unknown	unknown	gnl|CDD|376405
NC_017186.1|WP_013222229.1|295161_296463_-|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|99735
NC_017186.1|WP_013222233.1|299445_300084_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|378924
NC_017186.1|WP_013222237.1|302811_303312_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013222225.1|288419_290135_+|DUF2156-domain-containing-protein	gnl|CDD|235095	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX.	1.22264e-174
NC_017186.1|WP_013222227.1|292075_293704_+|cellulose-binding-domain-containing-protein	gnl|CDD|119365	cd06548, GH18_chitinase, The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.	1.12528e-109
NC_017186.1|WP_013222238.1|303325_303745_-|ATP-binding-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	5.41358e-19
NC_017186.1|WP_013222231.1|297541_298585_-|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.10773e-18
NC_017186.1|WP_013222243.1|307164_307596_-|hypothetical-protein	gnl|CDD|226158	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only].	0.00246291
NC_017186.1|WP_013222230.1|296550_297468_+|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.48332e-43
NC_017186.1|WP_003078104.1|305690_306044_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	6.16431e-22
NC_017186.1|WP_013222233.1|299445_300084_+|alpha/beta-hydrolase	gnl|CDD|378924	pfam12697, Abhydrolase_6, Alpha/beta hydrolase family. This family contains alpha/beta hydrolase enzymes of diverse specificity.	4.30409e-13
NC_017186.1|WP_013222241.1|305163_305472_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.98525e-23
NC_017186.1|WP_034284974.1|306103_306892_+|metal-dependent-hydrolase	gnl|CDD|377294	pfam04307, YdjM, LexA-binding, inner membrane-associated putative hydrolase. YdjM is a family of putative LexA-binding proteins. Members are predicted to be membrane-bound metal-dependent hydrolases that may be acting as phospholipases. It is a member of the SOS network, that rescues cells from UV and other DNA-damage. Expression of YdjM is regulated by LexA.	8.5924e-10
NC_017186.1|WP_013222228.1|293700_295047_+|cellulose-binding-domain-containing-protein	gnl|CDD|119360	cd06543, GH18_PF-ChiA-like, PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in archaea but also in eukaryotes and prokaryotes. PF-ChiA exhibits hydrolytic activity toward both colloidal and crystalline (beta/alpha) chitins at high temperature.	6.72293e-103
NC_017186.1|WP_013222234.1|300209_300953_+|3D-domain-containing-protein	gnl|CDD|270620	cd14667, 3D_containing_proteins, Non-mltA associated 3D domain containing proteins, named for 3 conserved aspartate residues. This family contains the 3D domain, named for its 3 conserved aspartates, including similar uncharacterized proteins. These proteins contain the critical active site aspartate of mltA-like lytic transglycosylases where the 3D domain forms a larger domain with the N-terminal region. This domain is also found in conjunction with numerous other domains such as the Escherichia coli MltA, a membrane-bound lytic transglycosylase comprised of 2 domains separated by a large groove, where the peptidoglycan strand binds. Domain A is made up of an N-terminal and a C-terminal portion, corresponding to the 3D domain and Domain B is inserted within the linear sequence of domain A. MltA is distinct from other bacterial LTs, which are similar to each other. Escherichia coli peptidoglycan lytic transglycosylase (LT) initiates cell wall recycling in response to damage, during bacterial fission, and cleaves peptidoglycan (PG) to create functional spaces in its wall. PG chains (also known as murein), the major components of the bacterial cell wall, are comprised of alternating beta-1-4-linked N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), and lytic transglycosylases cleave this beta-1-4 bond.	1.15302e-15
NC_017186.1|WP_013222240.1|304583_305000_-|anti-sigma-factor	gnl|CDD|273879	TIGR01924, Serine-protein_kinase_RsbW, serine-protein kinase RsbW. This model describes the anti-sigma B factor also known as serine-protein kinase RsbW. Sigma B controls the general stress regulon in B subtilis and is activated by cell stresses such as stationary phase and heat shock. RsbW binds to sigma B and prevents formation of the transcription complex at the promoter. RsbV (anti-anti-sigma factor) binds to RsbW to inhibit association with sigma B, however RsbW can phosphorylate RsbV, causing disassociation of the RsbV/RsbW complex. Low ATP level or environmental stress causes the dephosphorylation of RsbV.	4.86483e-06
NC_017186.1|WP_013222239.1|303807_304587_-|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	1.83075e-90
NC_017186.1|WP_013222232.1|298763_299435_+|HNH-endonuclease	gnl|CDD|377857	pfam07510, DUF1524, Protein of unknown function (DUF1524). This family of uncharacterized proteins contain a conserved HXXP motif. A similar motif is seen in protein families in the His-Me finger endonuclease superfamily which suggests this family of proteins may also act as endonucleases.	7.83231e-09
NC_017186.1|WP_013222236.1|301791_302769_-|aldo/keto-reductase	gnl|CDD|381312	cd19086, AKR_AKR11C1, AKR11C family of aldo-keto reductase (AKR). Bacillus subtilis uncharacterized oxidoreductase YqkF is a founding member of aldo-keto reductase family 11 member C1 (AKR11C1). It may function as oxidoreductase. This family also includes Bacillus halodurans AKR11C1, an NADPH-dependent 4-hydroxy-2,3-trans-nonenal reductase.	5.35624e-104
NC_017186.1|WP_013222229.1|295161_296463_-|aspartate-aminotransferase-family-protein	gnl|CDD|99735	cd00610, OAT_like, Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, alanine-glyoxylate aminotransferase, dialkylglycine decarboxylase, 4-aminobutyrate aminotransferase, beta-alanine-pyruvate aminotransferase, adenosylmethionine-8-amino-7-oxononanoate aminotransferase, and glutamate-1-semialdehyde 2,1-aminomutase. All the enzymes belonging to this family act on basic amino acids and their derivatives are involved in transamination or decarboxylation.	4.92728e-150
NC_017186.1|WP_013222235.1|301134_301773_-|nitroreductase-family-protein	gnl|CDD|376405	pfam00881, Nitroreductase, Nitroreductase family. The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.	3.66988e-20
NC_017186.1|WP_013222237.1|302811_303312_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.65464e-05

Protein sequences

>NC_017186.1|WP_013222234.1|300209_300953_+|3D-domain-containing-protein
MRFAHVLALTAIAAGSFLAAPAASAATLPACRHFYTGSIPDRPVTGGHGPGTLVGAVDVGNRLPAPGSVSGGLGTDGKVAFTFARVAGAKAYRAFRNGQALQWISDWGQPTLTVTDASPCQNANYQLYAMTAEDNSPGSLGQVSTAYRLDGANRLAAYRIPAGTTLNYRVTAYNDVAQTALGYQAGPGFCAVDARNIPWGTRFSVPGYGECYAADIGSWISGDIVDVWLPGSQADAWGIQRLTLTVR
>NC_017186.1|WP_013222233.1|299445_300084_+|alpha/beta-hydrolase
MTTFALIHGGGGSGWDFHLLIPELAARGHDAVAPDLPITDSSAGLAEFTETVLAALGDRTDVAVVGHSYGGFTAPLVAAKVRARLLVYLAGMIPAPGEPPGQWWGNTGFEAPKGLTETEQFFNGVPADLAEQCQAHGREQASKEWDEPWPLPAHPDVPTRVLLARDDRFFVPDFQRRVARERLGIEPDELDGPHCVPLSHPGALADRLVSYL
>NC_017186.1|WP_013222232.1|298763_299435_+|HNH-endonuclease
MAARGFRLSVTQRTLLVVTILALALFGYWATRGAGAAPPTSGAPVPVSAADAQKQLDELAIGARTSMDGYSREKFPHWDSQGSGCDTREVVLKRDGKDVKTDKDCRPTSGTWTSVYDEETWTKATDVDIDHMVPLGQAWASGAKSWTTEKREQFANDLTRPQLFAVTDNLNQQKSDKAPDEWKPPLVAFWCTYATDWIVVKHYYGLTITQGEKTALTDMLRRC
>NC_017186.1|WP_013222231.1|297541_298585_-|sel1-repeat-family-protein
MPGRLKKFDEFFQRKAAEGGNVVAMARMGAAMRERGELPEAESWYRKAAMGGDRVSMTALAHLLAERGAQEEAERWYHEAALAGEPHGMQHLAKSCERRGKRDDARHWYGEAARTGDLPSMAALGRLLREDGKGDEAESWLRQAAEAGFTGAMIDLGVVLRDRGQAAEAARWWRSAVQAGDLAATCQLGRQAERLGRPSDAESWYRQGARGGHVEAVTRLGLLLHRRGDLEEAETWYLEAAERGDPAAMTNLGVLARNRGDEGEAAAWYRKAAEHGSIPALTNLGHLAEHREDLATAEQWFRRAAETGDVQGMLSLARMLRARGAAHEAELWLARAETVQDEREHQH
>NC_017186.1|WP_013222230.1|296550_297468_+|LysR-family-transcriptional-regulator
MLNPWRLRLLSRLDTLGTVRAVAQDANLSASSVSQQLAVLEAETRTQLLERTGRRVRLTPAGLMLARRARVILDHMDTVEAELRSLGEEPAGLVRLGAFQSAIHTLAVPAVTRLAHPHLEVQLLELEPHESIPALRGGDADVIITTTDFVELPLGPDLDIVPLATDPIVLVTPPEAPRGPAVLSAYADAPWALDAPQSYMANLTLRLCRESGFEPRVVCRFSNYLMTLQHVEAGLSIALLPGLAVDRRYRVATRELATPVTRTIAAVVRRGTPLRAGVNVVLDALRQPPELPELPEWVGLRSSSP
>NC_017186.1|WP_013222229.1|295161_296463_-|aspartate-aminotransferase-family-protein
MAESFWADVDRHLVRYGGTFTPEIIDRAEGSFLFTEDGRRILDFTSGQMSAILGHSHPEIVETVRRQVGKLDHLFSGMLSRPVADLARRLAETLPAPLEKALLLTTGAESNEAAVRMAKLVTGKHEIVSFARSWHGMTQAAASATYSAGRRGYGPATPGNFAIPAPNAYRPDFTDASGSLDWRRQLDFGFEMIDAQSVGSLAACLVEPILSSGGIIEPPPGYFAALAEKCRERGMLLILDEAQTGLCRTGNWYAFERDGIVPDILTLSKTLGAGLPLAAVLTSAAIEQEAHDRGFLFFTTHVSDPLPAAVGNTVLDVLTRDRLDARALSLGAVLRRGLEELAAGHEVVGDIRGRGLLAGLELVVDRETKRSSDELGARVTQRCLELGLHMNIVQLPGMGGVFRIAPPLTASEEEIALGLSILDQAIGEAVKLL
>NC_017186.1|WP_013222228.1|293700_295047_+|cellulose-binding-domain-containing-protein
MTRRWWPALGLAAAAATIGAMFVIAPANAAGGVSATFSKGSDWGTGYEGKYTIANGSGSTLATWTVEFDLPSGAKISSLWDGSYTASGQHVTVKNTWNGNVANGGSASFGFNVAYSGSYAAPSNCKLNGGSCAAGGTPPTTTTPPTTTTPPTTTPPPAGGRGAPYLYMGWGSPPNPQTVMNATGIKWFTMAFINASGGCTPAWDSSRPLSGSADANAIAQIKAAGGQVIPSFGGWSGNKLGPNCSTPSALAGAYQQVINAYGLKAIDIDIENSDEFENEAVQDRILGALKIVKQNNPGIQTILTFGTSTTGPNYYGNRLIDQSKALGANVDVFTIMPFDFGGGANMYNSTVSAANGLRDKLKSTFGWSDATAYAHLGISGMNGLSDQQELTDLPTWTQITNWAKSNKIARLAFWSVNRDRGCPGGGVQSACSGIAQNDWDFTKVTAGF
>NC_017186.1|WP_013222227.1|292075_293704_+|cellulose-binding-domain-containing-protein
MSRKRWHLLGLFTAVGALAIGLVTVPASAAGGVSATFSKGSDWGTGYEGKYTINNGSGSTLATWTVEFDLPSGAKIGSLWDGSYTASGQHVTVKNTWNGNVGNGASASFGFNVSYSGTYAAPANCKLNGGSCDAGGGTPTTTPTTPTQPTTTPTTPTTPTTPTTTPPPPPGGLKNVGYFVQWGVYGRNYHVKNIETSGSASKLTHINYAFGNVTNGQCTANDDPYADYQKTYDAAGSVDGVADTWDQPVAGNFNQLRKLKKLHPGLKVIWSFGGWTYSGGFGQAAQNAAAFAQSCYNLLKDPRWADIWDGIDIDWEYPNACGLSCDTSGAAAYKNLMGALRSKFGSSFLITSAITADGSNGGKLDVADYGGASQYVDWYNVMTYDYFGAWAAQGPTAPHSPLTNFAGIPTPGFYSDAAIQKLKSKGVPSSKLLLGIGFYGRGWTGVTQSTPGGTATGPAPGTYEQGIEDYKVLKNTCPSTGTFAGTAYAKCGSNWWSYDTPATIGGKMSYAKQQGLGGAFFWELTGDTTGGELISAMKNGLS
>NC_017186.1|WP_013222226.1|290622_291867_+|hypothetical-protein
MEEHAEPQPEAAPKRRVVRAADEPVHRLLGWQRLAGNQAVVAMLGKSEPAVPVQRLMVRMPNPYGEGMHNMVGDAEVDEIEESLTAKGAAGAGGKHAWDGSWTFPPTPTTEASVFYGHGNRAKLGGVTPVDFVADVSDDQRQLKKDTAFKFVACGGGRAQAAAGTAYGHEVAEFLRASQTIVPGEDWSGALKATEGLVYYTNTYKTVVPEIPPAIDKLLIARTATAESNVRKRVTALVRDQLAAVATAQRARDFAEFRDAVATWYESDAALAGRAASVRKIVIPVAGLSNTWLGAKLNSAMDTMFGGDVGWLSLQEAFLQTLSSGNCLFDVYQLFAGIEADMKLVAKAIWAEFRNELQRQAAVPARDTGPAGRIGTHDPSTAASPDERFAKWQDFGDVLWTQWKANRLQGGNPT
>NC_017186.1|WP_013222225.1|288419_290135_+|DUF2156-domain-containing-protein
MVTGTRAQITWKAAGATTVGVITWVTRLAGLMTLGSILIPAGRRSLRGHLAEWLELPQEATVAAATVALVMGVLLVMLAAGLRRRKRRAWQLAVGATVLLTMSHLGLKHVFGAGLVSVVLLVGLIANRRYFVAKPDPVVGRWRAVRVFVQLALAGFVINVILLSVAPRAALEPMGFGDRLAESALALVAASGPAVFHQMWLEDFTTAVGLLFGLAALLVSAYFLLRSAEPAPRLSDEEVARLRRLLDEHGERDSLGYFALRRDKFAVFSRTGKAAVTYRVIAGVALCSADPLGDHEAWPGAIEEYLEVCRRGGWVPAAMGVSELGATVWARFGLEVLEIGDEAVVDAAGFTLDGRTMRGVRQAAARTKRAGYKVLVRRAEDLRPGELEELEVLAATWRGTDTERGFSMALGRMGDPRSVLVTAEQGGRVRGVLQFVPWGPTGLSLDVMRRDRSADNGVNELMISELLLAAGRHGVSQVSLNFAAFRALMEQGQRIGAGPVAKTAAKVLHFFSRWIQIETLYRFNAKFQPRWVPRYLVYPGVRELPRVGIATFEAEGLGGRSPRLLRLLRRA
>NC_017186.1|WP_013222235.1|301134_301773_-|nitroreductase-family-protein
MMTPEELLTTTRTVRKRLDLERPVPLDLVKHCIQVALQAPSGSNTQRWQWLVVTDVDQRAALGEIYRRACEEYLASPNAAGKLFADDPERAQVQQRVGDSVAYLADRMGDVPVLVVPCLETASSELPPGNQAGLWASLLPAVWSFMLAARSVTLGTAWTTLHLKYEQEAAEVLGLPKNVHQAALIPTAFYTGDTFKPAARQPLDEVLHLDRW
>NC_017186.1|WP_013222236.1|301791_302769_-|aldo/keto-reductase
MENRKIARLGREVSVVGLGCWQLGADWGEVDENDALGVLHAAADNGVTFFDTADVYGDGRSERLVGRFLAERGDVFVATKMGRRVEQVPENYVAANFREWNDRSRRNLGVDTLDLVQLHCPPTPVYSSDAVYDALDAMVDEGRIKAYGVSVETCEEALTALARPNVASVQIILNCLRLKPLERVLPAAAEAGAGIIARVPLASGLLSGRYTASTTFAENDHRNYNRHGDAFDVGETFSGVPYEVGLEAVERLRGLVPSGRTLAQFALRWIIDQPGVSTVIPGARNAGQAEANTAAAALPPLSAEATAAVRETYDELIRPLVHDRW
>NC_017186.1|WP_013222237.1|302811_303312_+|MarR-family-transcriptional-regulator
MAMTGDPERRGPEGLGTRMRHVLEILDGDVARFLADIGLDDYRPRYSPVVRALLARGPLAIRDLAEEMRVTHSAASQTVAQMHRAGFVSLEPGVDARQRIVSLTARTRELLPLIEAEWTATTEATAALEAELPYSLRALLDDIVEALERKPFRQRIGETTAAQELR
>NC_017186.1|WP_013222238.1|303325_303745_-|ATP-binding-protein
MTTSRTPQRTATAAAPLRVLLPADVTAPALARHEVRAALLRLGVGERQLEDILLATSELVTNAFEHGERPQRLELEYAAGRLTLRVHDTGRMLPELRAPSPAEARSRGLVLVQALSLDWGFERCPGGKYVWAVFPLPDA
>NC_017186.1|WP_013222239.1|303807_304587_-|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor
MSDPAGSSGNDLDVGALFTRLAALPADSPERERIRDTLVRTHLELARNLARKFRNRDEAMEDLVQIATVGLIHAVDRFDPAQGTDFLAFAVPTISGELRHHFRDNSWSVRVPRRLKELNANISAAREELTVQLSRAPKPSEIAARLGVPIEDVYEGLRAGQGRYGASLDHLLENAAHTRFGAPDAELGQAELREALRPMLESLPERERKIVALRFGSGMSQSDIARRVGVSQMQVSRLLAATLKKLRSGLDESELADGT
>NC_017186.1|WP_013222240.1|304583_305000_-|anti-sigma-factor
MEDNAPLVPEGAQVIEVRTAAIPHVVPTLRTIVADIAMRQDFDLDAVEDLRMAVDEACSLLLPASSDGRLTCVFSWNGPRIEVSVSVLADSADHEDDAGLSWQLLTALATTAERTITPENGRYLSRVDLVRESQAADS
>NC_017186.1|WP_013222241.1|305163_305472_+|WhiB-family-transcriptional-regulator
MADVSRLPNVVAEEWEWQLRGSCRGADSSLFFHTDNERGSARERREARAKAICQACPVLAQCRKHAMTVQEPYGIWGGLGEIERRQLFLRQRRAARKTMSAH
>NC_017186.1|WP_003078104.1|305690_306044_+|STAS-domain-containing-protein
MPAADQNATPPGFGITLDTDATEPRVVVTGELDLLTSPQLQEALAGLIADKRAQRVVADLTGVTFFDSSALNVVLRAQRQAGEQDVELAVVPSPAVSRVIELTGVAEHLSVSEDPQA
>NC_017186.1|WP_034284974.1|306103_306892_+|metal-dependent-hydrolase
MGRTHALTGWCAGLALAPAVGAGSVHQAVVFAATTAGFALLPDLDHPGASASRLLGWLTGALSWLLRRVSAGFYALTKGPRDENVSGKHRHLSHTVLFAAGLGLLTSWGTTEGGPWAVVGVVVFGLMLAEGALGDWLLPVSGAAVAWWFFTAPPDRAGELASISGWLGIAVAAGCLTHCLGDALTEAGCPFLFPIPIAGETWYEIRPPRVLRFRTGKKVEKRLIFPVFALLGVLLVPGVWEHTVSTFERLFIPPSSQQATTP
>NC_017186.1|WP_013222243.1|307164_307596_-|hypothetical-protein
MPRTVPEIAALVRSGLSTLDVAPFASLFAADAVYEVPFLGERIEGREAVVATLTAGGVRARAAGLTKAQVTTTLAESGFVVELVVSGPGIEFPSSVGLITVVEGEITSYRDYPDTSAAAKLARSSNPEGGERVVKAESPQIAE

Crispr_ID: NC_017186_3

• CRISPR_ID: NC_017186_3
• CRISPR_location: 763122-763205
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_3

Consensus_repeat	Method
GCCGAGGAGACCACCGAGGCTCCGGCC	CRISPRCasFinder

spacers of NC_017186_3

>3.1|763149|30|NC_017186|CRISPRCasFinder
GAGGAGGCTCCCGCTGCCGAGGAGGCCAAG

CRISPR arrays and Neighbor proteins around NC_017186_3

CRISPR arrays

The CRISPR arrays of NC_017186_3

>merge|NC_017186|3|763122-763205|CRISPRCasFinder
GCCGAGGAGACCACCGAGGCTCCGGCCGAGGAGGCTCCCGCTGCCGAGGAGGCCAAGGCCGAGGAGACCACCGAGGCTCCGGCC

>NC_017186|3|3|763122-763205|CRISPRCasFinder
GCCGAGGAGACCACCGAGGCTCCGGCC	GAGGAGGCTCCCGCTGCCGAGGAGGCCAAG
GCCGAGGAGACCACCGAGGCTCCGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013222623.1|760229_760415_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_004558887.1|761577_762648_+|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl|CDD|235359
NC_017186.1|WP_034285908.1|759852_760233_+|30S-ribosomal-protein-S13	unknown	unknown	gnl|CDD|235358
NC_017186.1|WP_071831447.1|766861_768499_+|type-VII-secretion-protein-EccB	unknown	unknown	gnl|CDD|368288
NC_017186.1|WP_013222634.1|771594_772959_-|type-VII-secretion-integral-membrane-protein-EccD	unknown	unknown	gnl|CDD|274855
NC_017186.1|WP_013222636.1|777536_779528_+|type-VII-secretion-associated-protein	unknown	unknown	gnl|CDD|212667
NC_017186.1|WP_013222631.1|768578_768881_+|hypothetical-protein	unknown	unknown	gnl|CDD|215505
NC_017186.1|WP_013222627.1|764214_764934_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013222619.1|756336_757644_+|preprotein-translocase-subunit-SecY	unknown	unknown	gnl|CDD|236412
NC_017186.1|WP_013222632.1|768877_769954_+|hypothetical-protein	unknown	unknown	gnl|CDD|377587
NC_017186.1|WP_013222624.1|760864_761470_+|30S-ribosomal-protein-S4	unknown	unknown	gnl|CDD|235411
NC_017186.1|WP_013222621.1|758239_759016_+|type-I-methionyl-aminopeptidase	unknown	unknown	gnl|CDD|235576
NC_017186.1|WP_071831453.1|763245_764145_+|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl|CDD|234577
NC_017186.1|WP_004558882.1|759532_759646_+|50S-ribosomal-protein-L36	unknown	unknown	gnl|CDD|179039
NC_017186.1|WP_004558881.1|759273_759495_+|translation-initiation-factor-IF-1	unknown	unknown	gnl|CDD|178954
NC_017186.1|WP_013222635.1|773317_777331_+|type-VII-secretion-protein-EccC	unknown	unknown	gnl|CDD|274858
NC_017186.1|WP_013222620.1|757640_758195_+|adenylate-kinase	unknown	unknown	gnl|CDD|234711
NC_017186.1|WP_034285947.1|765007_766189_-|type-VII-secretion-protein-EccE	unknown	unknown	gnl|CDD|274857
NC_017186.1|WP_004558885.1|760433_760841_+|30S-ribosomal-protein-S11	unknown	unknown	gnl|CDD|180007
NC_017186.1|WP_013222633.1|769963_771574_-|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|274856

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_004558887.1|761577_762648_+|DNA-directed-RNA-polymerase-subunit-alpha	gnl|CDD|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
NC_017186.1|WP_034285908.1|759852_760233_+|30S-ribosomal-protein-S13	gnl|CDD|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	6.79333e-76
NC_017186.1|WP_071831447.1|766861_768499_+|type-VII-secretion-protein-EccB	gnl|CDD|368288	pfam05108, T7SS_ESX1_EccB, Type VII secretion system ESX-1, transport TM domain B. EccB is a family of largely Gram-positive bacterial transmembrane componenets of the type VII secretion system characterized in Mycobacterium tuberculosis, systems ESX1-5. Translocation of virulent peptides through the membranes is thought to be mediated via a complex that includes EccB, EccC, EccD, EccE, and MycP. EccB, EccC, EccD, and EccE form a stable complex in the mycobacterial cell envelope.	1.16314e-103
NC_017186.1|WP_013222636.1|777536_779528_+|type-VII-secretion-associated-protein	gnl|CDD|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	1.40275e-79
NC_017186.1|WP_013222631.1|768578_768881_+|hypothetical-protein	gnl|CDD|215505	PLN02935, PLN02935, Bifunctional NADH kinase/NAD(+) kinase.	0.00475908
NC_017186.1|WP_013222634.1|771594_772959_-|type-VII-secretion-integral-membrane-protein-EccD	gnl|CDD|274855	TIGR03920, T7SS_EccD, type VII secretion integral membrane protein EccD. Members of this family are EccD, a component of actinobacterial type VII secretion systems (T7SS) with ten to eleven predicted transmembrane helix regions. [Protein fate, Protein and peptide secretion and trafficking].	6.16248e-59
NC_017186.1|WP_013222619.1|756336_757644_+|preprotein-translocase-subunit-SecY	gnl|CDD|236412	PRK09204, secY, preprotein translocase subunit SecY; Reviewed.	0
NC_017186.1|WP_013222632.1|768877_769954_+|hypothetical-protein	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	0.00526787
NC_017186.1|WP_013222624.1|760864_761470_+|30S-ribosomal-protein-S4	gnl|CDD|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	7.67464e-117
NC_017186.1|WP_013222621.1|758239_759016_+|type-I-methionyl-aminopeptidase	gnl|CDD|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	4.38761e-137
NC_017186.1|WP_071831453.1|763245_764145_+|tRNA-pseudouridine(38-40)-synthase-TruA	gnl|CDD|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	8.37373e-104
NC_017186.1|WP_004558882.1|759532_759646_+|50S-ribosomal-protein-L36	gnl|CDD|179039	PRK00465, rpmJ, 50S ribosomal protein L36; Reviewed.	1.02099e-12
NC_017186.1|WP_004558881.1|759273_759495_+|translation-initiation-factor-IF-1	gnl|CDD|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	5.36212e-47
NC_017186.1|WP_013222635.1|773317_777331_+|type-VII-secretion-protein-EccC	gnl|CDD|274858	TIGR03924, T7SS_EccC_a, type VII secretion protein EccCa. This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking].	0
NC_017186.1|WP_013222620.1|757640_758195_+|adenylate-kinase	gnl|CDD|234711	PRK00279, adk, adenylate kinase; Reviewed.	8.29381e-90
NC_017186.1|WP_034285947.1|765007_766189_-|type-VII-secretion-protein-EccE	gnl|CDD|274857	TIGR03923, T7SS_EccE, type VII secretion protein EccE. This model represents the transmembrane protein EccB of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccE1, EccE2, etc. This model represents a conserved core region, and many members have 200 or more additional C-terminal residues. [Protein fate, Protein and peptide secretion and trafficking].	1.01978e-34
NC_017186.1|WP_004558885.1|760433_760841_+|30S-ribosomal-protein-S11	gnl|CDD|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	2.66662e-85
NC_017186.1|WP_013222633.1|769963_771574_-|S8-family-serine-peptidase	gnl|CDD|274856	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin. Members of this family are subtilisin-related serine proteases, found strictly in the Actinobacteria and associated with type VII secretion operons. The designation mycosin is used for members from Mycobacterium. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair].	9.27465e-83

Protein sequences

>NC_017186.1|WP_004558887.1|761577_762648_+|DNA-directed-RNA-polymerase-subunit-alpha
MLISQRPALGEETVNETRSRFTIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTDIILNLKELVVSSEEDEPVTMYLRKQGPGEVTAADIVPPAGVTVHNPDLHIASLNGKGKLEIELVVERGRGYVPALQNKQAGAEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLILDVETKPSITPRDAVASAGKTLVELFGLARELNVDAEGIEIGPSPQEADTIAAYAMPIEDLDLTVRSYNCLKREGIHTVGELVSRSEADLLDIRNFGAKSIDEVKLKLVGLGLALKDSPPGFDPTAAAASYDGEGWSEGVGGIADGISDGHDDGQDYAETEQL
>NC_017186.1|WP_013222624.1|760864_761470_+|30S-ribosomal-protein-S4
MARYTGPATRISRRLKVDLIGGDQAFERRPYPPGQHGRGRIKESEYLLQSQEKQKARYTYGVLERQFVRYYKEAVRRPGKTGENLLQILESRLDNVIYRAGIARTRRQARQLVSHGHFLVNGVKVNVPSYQVTKWDIIDVRPKSFSMLPFVVAKESFGDRPIPAWLQVVQSNLRVLVHQLPERAQIDVPVQEQLIVELYSK
>NC_017186.1|WP_004558885.1|760433_760841_+|30S-ribosomal-protein-S11
MPPKSRTAAGAKKVRRKEKKNVAHGHAHIKSTFNNTIVSITDPTGAVIAWASSGHVGFKGSRKSTPFAAQMAAENAARKAAEHGMKKVDVFVKGPGSGRETAIRSLQAAGLEVGTIQDVTPQPHNGCRPPKRRRV
>NC_017186.1|WP_013222623.1|760229_760415_+|hypothetical-protein
MSVQGKKVVQMGGVQRRGSACVSPKALYARPMALRNLYTDAGSIIRRGQAEAVAAHQENAR
>NC_017186.1|WP_034285908.1|759852_760233_+|30S-ribosomal-protein-S13
MARLAGVDLPREKRLEIALTYIYGIGRTRSKQLIKAAELNADTRVKDLSDDDLAKLRVYIEENFKVEGDLRREVNADIRRKIEIGCYEGLRWRRGLPVRGQRTKTNARTRKGPKKTVAGKKKAGKK
>NC_017186.1|WP_004558882.1|759532_759646_+|50S-ribosomal-protein-L36
MKVQPSVKKICDKCKVIRRHGRIMVICENLRHKQRQG
>NC_017186.1|WP_004558881.1|759273_759495_+|translation-initiation-factor-IF-1
MAKKDGAIEVEGRVVEPLPNAMFRVELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYK
>NC_017186.1|WP_013222621.1|758239_759016_+|type-I-methionyl-aminopeptidase
MIEVKTPDELQAMRAAGLVVARTLASVRAAAKPGVSTAELDELAEQTIRDAGAVPSFKGYHGFPASICASVNEQIVHGIPAKTQVLADGDIISVDCGAILDGWHGDSAVTLAIGQVSDADLALSAATEAAMWAGIEAVRAGGRLTDISYAVQSAAERAARDDGIEYGMIVEYGGHGIGRQMHMDPFLPNVGKPGKGPRLKPGMALAIEPMLTGGGGETRELDDGWTVVTADGSRAAHWEHTVAITEDGPWVLTAPEDA
>NC_017186.1|WP_013222620.1|757640_758195_+|adenylate-kinase
MTRLVLVGPPGAGKGTQAVALSEQLRVPHISTGDLFRAHVGQETPLGQEAKRYLDSGELVPDSVTNEMVRERLAEPDAKVGFLLDGFPRNTKQAEVLGEILGDADVSLDAVIQLQVPEDVVVGRLMSRGRADDTEEVIRRRQQIYVSDTAPLLEYYADILVTVDGVGSVEEISGRVLKALRDRT
>NC_017186.1|WP_013222619.1|756336_757644_+|preprotein-translocase-subunit-SecY
MLSAFRSALATPDLRKKILFTLAIVAVYRIGATIPAPGISYGAVQACSSQAQQEGVYQLLNLFSGGALLQLSLFSTGIMPYITASIIIQLLTVVIPRFEELKKEGQSGQGKLTQYTRYLTIALAILQATGVVALADRKQLFPDCQSPIIPDNSVYSLAIIVITMTAGTAVMMWLGELITERGVGNGMSVLIFLNIAARIPVEGGNILSNAGGVGLAIVCVFGLVIIASVIFVEQGQRRIPVQYAKRMIGRRMYGGTSTYLPIKVNQAGVIPVIFASSLLYLPDLISRLVGDQNANSGWQVFIKNYIVNQSSWVHIALYFALIIFFTYFYITITFNVDERAEEMKKFGGFIPGIRPGRPTAEYLSFVLGRITLPGSLYLGIIAILPNFFLSLTGSGNNQNFPFGGTAVLIMVGVGLDTVKQIESQLMQRNYEGFLK
>NC_017186.1|WP_071831453.1|763245_764145_+|tRNA-pseudouridine(38-40)-synthase-TruA
MTADSTPDEPATPLGEGGLVRLRLDVSYDGTGFSGWARQPGRRTVQGVLEEALQRQPPGAGVPKSVVVAGRTDAGVHATGQVVHVDVVPLAPGSAGRVPVFAEGIPDLTRMAGRWNRLLPGDVRVLGARIAPEGFDARFSAVRRHYRYRVSDAPWGVDPLRRHDTLAWNRPLSTDAMNAAAAELLGLHDFAAYCKQRETGTTIRELQRLEWTRVDEHLLEVRVSADAFCHSMVRSLVGVLLLVGDGRRTDAWPAKVLESGIRDSAVAPAHGLTLLGVDYPPDAELAARAEQTRNVRTSL
>NC_017186.1|WP_013222627.1|764214_764934_-|hypothetical-protein
MSSRVRDAGQNSGVAPEFTVDPAMLDAISPSGDRGGIVLGSGLKGEPLTISALRSTPTRIVLVGGLYLARQVAMRAMAVGAWVVVATGRPTEWQVLSRAAGLRDGRPSPLVQIRRLSPVELPRPSEDAPLLVVTDGGPTPQDLFPPRSPWQTTIYVLPYLHPQAGMTANAADLVLMQRLPAGQAELAGRIWNLPPQMMRQLTTLKDDQVVALGRNLWRPLRLVTTGKEQQLLGPVRRGD
>NC_017186.1|WP_034285947.1|765007_766189_-|type-VII-secretion-protein-EccE
MANLVVLEVGLAIGLVLLAIDMSLKYVGIGIAGFALIVALLRWRGRWFTQWVGLTLRYTFRSHDRVADPLPPSTVEAMTAEETTVTGPDDARVNLLRIAVPDLVVAHGVDHERQQVGLAWNDGTWTAVLLVEPAPALITQADGAPSLPLSALAPCLEDRGVVLDSIQMIWHCYPGSAALPSDSPALSSYMEVLGPLPAAARRTTWVAIRLDPRRCPAAIRERGGGVVGAHRALIGALSRVRNALESQGVPTRPLDPDELLRAGISAAELTSVAGSPTKVTMQERWSGVTAAGIGHASYAITGWPKGKVTNSLNALTSVRALSATLAMSISPASDEGKIGLRGVVRLSARNPRELDAADQRLQGLAERLGVDLTPLRGLQVSAFAATLPIGGTA
>NC_017186.1|WP_071831447.1|766861_768499_+|type-VII-secretion-protein-EccB
MPSTPTTKSQVQAYQFVLRRMQSALVRRDAVMLHDPMRTHTRATIVGVVLGALGMIVFVVWGLLSPAPSVPEAGNIVIGEQSGTVYVVTGNPKKLIPTFNLASARLLLLAQQKSSAAGAAAGGAAATPAPAAASPASVKNPTVVSDEQLKDIPREKLTGIPDGPQLIPTDSQRISPNWAVCDQVQLDPSLPNPDTGRTNTYVFGGIAPSGLGTELRENEALLAKADNGKTYLVYRLPSSRNRPNANTVRAEIDVDNPNDAVRTALQLPPSPRKITQGLLNAIPEVAKLTPPKIQNGQAPGDFDGLTAGDVFATQQAGETTLNYWAITRSGIQRVSNAVADIIRVAKNGSSGRIQTLGLDKLAGVHTMQPTDPDYIPVDDFPRSVPTVLDATKNSSVACLGWSLAGSGPDQDAHTSVYVDTQLPGQKTGGEKFVPMTVTTPGPNRVPLNGFYLKPGFAAVVQSATGKASFGKGQIQLISDRGVRYSVPDAQTADAIGMNNRQPAPESIIGLLPTGASLNTQDVLRQFDAVPIDPNAGAYPTPQPGN
>NC_017186.1|WP_013222631.1|768578_768881_+|hypothetical-protein
MDGVVVARYAETAEGAAADLDAAAAEVGGDVTAESYGTLGAQIGLAESYGRASGALRRQLADGAEALRSAAEALRQVAIRHGGQDAEAAELIKRAGRLDG
>NC_017186.1|WP_013222632.1|768877_769954_+|hypothetical-protein
MSAGSDSLAASVPVPAGEDITAAAEPYLAYLTELAQELGVIDPVETYFRPLLGRWADLGAEADRLRQAASVAAEVSARLDDELGRLDAGWAGRDADSFVTYIRAIGAAGGDLHEALDILAGALDEMVTTVRHVVVDLVEVLVDAAELTSETMLLPAGGPKRARAQLEETQESAKALHETARDVMEAFDRLCDGVDDPDAASRTIEIRHRYPPERFKLHDDALNEAGEQATDAASSPSPGDEAMTPSSADEVLTPSSAAGQAEGRHTGAGTPDPAQPADAAVPQAPPAEQDHSASGGVPMMPMMGFGAFGSGGQVRRPSKTRPATTSSDLLGEPGLVAPPVIGEDETPQQKKPTAPPAT
>NC_017186.1|WP_013222633.1|769963_771574_-|S8-family-serine-peptidase
MAAARRPGATRRTATALLAGTIGLLSPLTLAVPAWAQAAPADGYFGTPPPVDMDKLIPDTRQPDKTYTQTKGCVQRSTLGQDIQIKNRPWGQEYLQISKAQEIVKAVRGSAGGGVRVAVIDTGVTKHPWFQDRLKSGGDYVATPTKNQPPGLEDCDGHGTEVAGIIGAKPDNPEVGFVGVAPDATIVSYRQLSENYEPAKQNSTANSSTPPSSSTNPPSGSSTELPPGGGGGTAEGDGTSPGQSNGGRQLEKAGTAGTLRTLAEIIHGIAERHEADVINMSVDNCRPASGSITEGEQQVQAAVRFAADAGIVIVAAAGNATDTCPQNDQPDARKPKTIVTPPWFADDVLSVGAIDEFGSVAPFSVHGPWVGVAAPGTKIVSLDPAEGSGSLANLTFENGDKASEIQGTSFASPYVAGLAALVKAMYPKLTAKGIVNRIKETAQHPAAPGGRDNFVGYGVIDPVAALTQVLPSEVGNQAPIPPPQMAQLPPANDHNSTPMIVALAGTAGGVLALLITLFVMHTIRRNRPAETETSRR
>NC_017186.1|WP_013222634.1|771594_772959_-|type-VII-secretion-integral-membrane-protein-EccD
MTVVAPSTRIDVALPADVAVADLLPMLLDMAKETAPDGGARHGGWALAKLGDAPLDPSRTLASLGVVDGELLQLRKRNENPPPPLYDDVVDAIAESSPDSFRPWTKETANRFGHVAGGLALFAAAVALFMSGSFYGGSALGAAIAGGIGAVACVAIGATLAKGYQAEPTGVLIAAAGGLPLAFVSGFYIVPGLSLRANLLLGAVLVIIVASVCIMVIGAGITTFIAAATAGTFGALAFLFGTLVAHPAAGIAAGTVAVALACISILPRATIWLAKLPLPHVPSNAEELKEDSGFPDYRAIERRTAIAHNYMTGLMVGCGATVAVSAIIAASAPGTFGIILGVVATLVLLLRARAYANGSQAIALLTTGLVSATGIAVGWLISASAQNRLLYVFGVLILLAAGALVVGVIFPNQRFSPPLRRTVEIIEAICIASVLPLALGVMDLYTTLRHLNFK
>NC_017186.1|WP_013222635.1|773317_777331_+|type-VII-secretion-protein-EccC
MSTLQFKKSPRLAAPRPPGGEVHLEPPPEVPRVIPGNIVMKALPVVMIVASLGMMVFMFQASNRNPMMMAMGGMMVVGTLGMMAGGGGKGGGAKRAEMDEDRKDYLRYLGQMRDRAREAMVDQRAALEWVHPDPQSLWSLAASRRMWERRQNDQDFLHLRVGRSSHRLATRLVPPQTGPVDELEPIATLALRRFVRAHSIVPDLPTQITLRGFAAVSMQGDRALTRGLTRAMLAQLVSFHSPDDVLIAVATAGRAKEEWEWAKWLPHVQHPTLSDGIGQLRMMAGSLAQIEDWLDEELRDRQRFSRNATPAPDQPHVVIIIDDAEVTREEQIVLEEGLVGVTLIDLSESLGNLAARRGLRLVVEADRLGARSAGGVEWFGRPDTLSLVETESLARLISPYRVGGAAGQDVGDEEPLLSNPSLLELLGIPGDPMTFDVQQAWRPRPIRDRYRVPFGVGEYGQPVELDIKEAAAEGMGPHGLCIGATGSGKSEFLRTLVLGLLSTHSSSTLNFVLVDFKGGATFMGLDKAPHVSAVITNLADEVTLVDRMKDALAGEMNRRQEALKNGGNFKNVWEYEKARENGADLDPLPALFIVCDEFSELLSAKPDFIDLFVAIGRLGRSLQMHMLLASQRLEEGKLRGLDSHLSYRIGLKTFSAAESRAAIGVPDAFELPSVPGGGYLKYDTSTLVRFKAAYVSGPYRPAGLKAAGPAATVVRADKRPQLFVPDFVELPKEPEPQFIEAAPKEEQRQSEEAVEPSELDVIVSRLVGQGPPAHEVWLPPLKDPNSLDTLLPNLNPTDDRGLSPVGFFGNGRLQVPLGIIDRPYEQRRDPLWADFSGAAGHGVIVGGPQTGKSTMLRTLIMSMALTHTPEEAQFYCLDLGGGTLAGLADLPHVGGVAVARREPDKARRIVAELTTLLTEREGRFGALGIDSMTEFRNRKRRGEIRPDQDPFGDAFLVVDNWRALRDDFEELETTITRLATQGLSYGVHVIISANRWADIRPAIKDMLGTRFELRLGDPTESDIDRRIAVNIPAGRPGRGLTREKLHMLGGLPRIDGSSDPETVAAGVADAVAKIKGAWRGRVAPQVRLLPELITYEDVLKLDSARDSKLVPIGVNEEDLQPVYLDFNAEPHFYAFADGESGKTNLLRQIARGISERYTAKEALILLVDYRRTMLGFIQGDSLLGYAVSAAQLESMVGDVFNSMTRRLPGPDVTQEQLKTRSWWKGPELFILVDDYDLVATSSNNPLRKISDFLPQAKDVGLHLVVVRRTGGASKAMYDPIIGKLKEIAAPGMVMNGSRDEGALVGNIKPGAMPPGRGNMLTRKYGKQLIQVSWIQPD
>NC_017186.1|WP_013222636.1|777536_779528_+|type-VII-secretion-associated-protein
MTVRVAVDFGTSSTCVVASVNGREPQVVVIDGQPLMSSAVYAAADGTLFVGQEAERQAAVDPSRYEPNPKRRIDEGELLLGENVLRVTDVVHAVLGRAVSEARRLAGDAEVDLLVLTHPADWGAIRTRLLRQAAGGLAREVALVPEPVAAAVYHAATFAPQDVKDDRTVEFSGRPGEALAVLDLGGGTVDVSVVRRLPPDPARDRAGRPQRGGFQVLATRGDPAFGGADIDQALLEHLGSLVSAADPAAWRELVEGRELADRRRRRVLRQDVRGAKETLSRHAYTDVPMPPPFADAHVTREDLERLIAAPLGRTVELTVAAIGDAGLRPKQLTAIFLVGGSSRIPMISRLVHERTGVVPTSLDQPETVVARGALRAVLVDPDRTGALPGEAMARLGAAPGGALNPAAQRTEVVRPGDVAPRPAPPRSGPGGFPNRPAPPPSPPSGQPVARPWPPPAGPPARPNPPGPPAGARPAPEPAGKSRRKLWGLIAAAVVVVAALVVAGVLVFENSGNQAESGRTLSQYDFKFVAPEDWVQTDDRVADKQVVIHPQESRDGNDLLVAQEYVMDYDATADPQRLVDALKRRADEKPALYSAFNPSLSYAGKTVIGYHESKQDRPDLQVDWYVVAKGRIRVHVGCQYATSALRDRVAAACAQAVRTVEILN

Crispr_ID: NC_017186_4

• CRISPR_ID: NC_017186_4
• CRISPR_location: 1339607-1339682
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_4

Consensus_repeat	Method
GGTGAGCCCGGCGGGGCGGGCCT	CRISPRCasFinder

spacers of NC_017186_4

>4.1|1339630|30|NC_017186|CRISPRCasFinder
CCGTGGGGGCTCGGTGGTTCCTCCGCTGGG

CRISPR arrays and Neighbor proteins around NC_017186_4

CRISPR arrays

The CRISPR arrays of NC_017186_4

>merge|NC_017186|4|1339607-1339682|CRISPRCasFinder
GGTGAGCCCGGCGGGGCGGGCCTCCGTGGGGGCTCGGTGGTTCCTCCGCTGGGGGTGAGTCCGGCGGGGCGGGCCT

>NC_017186|4|4|1339607-1339682|CRISPRCasFinder
GGTGAGCCCGGCGGGGCGGGCCT	CCGTGGGGGCTCGGTGGTTCCTCCGCTGGG
GGTGAGTCCGGCGGGGCGGGCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013223169.1|1347001_1348198_+|allantoate-amidohydrolase	unknown	unknown	gnl|CDD|236456
NC_017186.1|WP_013223171.1|1349537_1350683_+|imidazolonepropionase	unknown	unknown	gnl|CDD|237604
NC_017186.1|WP_013223162.1|1337082_1338216_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_017186.1|WP_013223160.1|1336018_1336417_+|heme-binding-protein	unknown	unknown	gnl|CDD|377163
NC_017186.1|WP_013223157.1|1333330_1334227_+|amidohydrolase	unknown	unknown	gnl|CDD|368185
NC_017186.1|WP_013223163.1|1338212_1338887_-|sensor-domain-containing-protein	unknown	unknown	gnl|CDD|379374
NC_017186.1|WP_013223155.1|1331911_1332805_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|225088
NC_017186.1|WP_013223158.1|1334216_1335527_-|acyltransferase	unknown	unknown	gnl|CDD|376607
NC_017186.1|WP_003082104.1|1331175_1331865_+|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl|CDD|225438
NC_017186.1|WP_071831517.1|1348194_1349550_+|formimidoylglutamate-deiminase	unknown	unknown	gnl|CDD|236420
NC_017186.1|WP_013223165.1|1341617_1342820_-|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_017186.1|WP_013223156.1|1332851_1333334_+|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|376590
NC_017186.1|WP_013223164.1|1340239_1341478_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_017186.1|WP_013223167.1|1343823_1345350_+|histidine-ammonia-lyase	unknown	unknown	gnl|CDD|236484
NC_017186.1|WP_013223168.1|1345352_1347005_+|urocanate-hydratase	unknown	unknown	gnl|CDD|235448
NC_017186.1|WP_013223166.1|1342956_1343739_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224332
NC_017186.1|WP_143264264.1|1340025_1340235_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223159.1|1335621_1335846_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223172.1|1350796_1351948_+|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|223727
NC_017186.1|WP_014466646.1|1336401_1337043_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013223169.1|1347001_1348198_+|allantoate-amidohydrolase	gnl|CDD|236456	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed.	2.24909e-161
NC_017186.1|WP_013223171.1|1349537_1350683_+|imidazolonepropionase	gnl|CDD|237604	PRK14085, PRK14085, imidazolonepropionase; Provisional.	0
NC_017186.1|WP_013223162.1|1337082_1338216_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.58791e-40
NC_017186.1|WP_013223160.1|1336018_1336417_+|heme-binding-protein	gnl|CDD|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	1.99062e-15
NC_017186.1|WP_013223157.1|1333330_1334227_+|amidohydrolase	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	1.9445e-22
NC_017186.1|WP_013223163.1|1338212_1338887_-|sensor-domain-containing-protein	gnl|CDD|379374	pfam13796, Sensor, Putative sensor. This family is often found at the N-terminus of proteins containing pfam07730 and pfam02518. The N-termini of proteins containing these two domains often function in stimulus sensing.	3.26937e-29
NC_017186.1|WP_013223158.1|1334216_1335527_-|acyltransferase	gnl|CDD|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	1.55052e-11
NC_017186.1|WP_003082104.1|1331175_1331865_+|cell-division-ATP-binding-protein-FtsE	gnl|CDD|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	7.72272e-126
NC_017186.1|WP_071831517.1|1348194_1349550_+|formimidoylglutamate-deiminase	gnl|CDD|236420	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated.	4.92182e-178
NC_017186.1|WP_013223165.1|1341617_1342820_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.42859e-43
NC_017186.1|WP_013223156.1|1332851_1333334_+|SsrA-binding-protein-SmpB	gnl|CDD|376590	pfam01668, SmpB, SmpB protein.	1.50881e-93
NC_017186.1|WP_013223164.1|1340239_1341478_-|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.13392e-60
NC_017186.1|WP_013223167.1|1343823_1345350_+|histidine-ammonia-lyase	gnl|CDD|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NC_017186.1|WP_013223168.1|1345352_1347005_+|urocanate-hydratase	gnl|CDD|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
NC_017186.1|WP_013223166.1|1342956_1343739_-|IclR-family-transcriptional-regulator	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	1.36991e-56
NC_017186.1|WP_013223155.1|1331911_1332805_+|ABC-transporter-permease	gnl|CDD|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	1.86236e-58
NC_017186.1|WP_013223172.1|1350796_1351948_+|FAD-dependent-monooxygenase	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	2.56718e-29
NC_017186.1|WP_014466646.1|1336401_1337043_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.63157e-42

Protein sequences

>NC_017186.1|WP_013223163.1|1338212_1338887_-|sensor-domain-containing-protein
MVSERRDPPFGGSVVFLLMNLPLGVVAFGFLTVFVSAGAGTAVVWVGVGLLAAVVLAVRGAARLERARIYALLDRYIDLPYLPLPAGKQAVRWKGRLKDPSTWRDLAYFALLFPVGLVEFVLVTTFWATSLALVGLPVYFRWLPGGEYRFPAWEVPWLTVDSTVEALPWAALGVLFVALSVALTRALAGTHARLASALLGPTVAQRHRMERWWENAEEKNLVAG
>NC_017186.1|WP_013223162.1|1337082_1338216_-|sensor-histidine-kinase
MTEAQQLEHPRPHPARTILYMIVSFVFRFVQFVLIVVGISVGVSTAVIWVGFPILLATTSFVRWSGDRERGWLGTMLRVPLPPVQRRPYEAGQPLLRRWMVRLSDPTTWRDLAYLMAAFPLACAEVVIALASVVLLPMAIWVTPWLGWLHGELALALLGPDRTKRLEQKAERLQASRARGVDAAEAERRRIERDLHDGAQQRLVAVAMSLGRAKSKFDQDPQAVRELIDEAHSDAKLAVSELRDLARGIYPAVLGDRGLDAALSAQAAKSPIPVDVSVDVDPRPPAAVETTAYFIVGETLTNIAKHSGATEAVVKVWRTDDHVVVEITDDGHGGAEVRPGGGLAGLADRAATIDGVITVVSPVGGPTVIRADLPCQW
>NC_017186.1|WP_014466646.1|1336401_1337043_-|response-regulator-transcription-factor
MRVVIAEDAVLLRAGVTRLLADEGIETVAAVDNGDDLLGALKEHRPDLAIVDVRMPPTFTDEGLRAALAARKEIPGLPVLVLSQYVEESYAVELLSGGAGGVGYLLKERVADVADFLDAVRRVAGGGTAIDPDVIAQLMARGRRNPLDALTARESEVLGLMAQGLSNTAIANSLVVSHGAVEKHIGNIFSKLGLEASAEEHRRVRAVLTYLGR
>NC_017186.1|WP_013223160.1|1336018_1336417_+|heme-binding-protein
MADADRLVDAALTAGAERGFPPLAVAVLDVTGEVITLRRADGGMPMTSRIAVAKARSALLTLNASGGLELPGPIVDGIQHLFHGDYVPYAGGVLVTDGEVILGAAGASGAHAREDEEAVRVAVERWRAQRPR
>NC_017186.1|WP_013223159.1|1335621_1335846_-|hypothetical-protein
MSDETPCVRFFGGPLDGRVQELGDAEPIPGTVIRHIHLHGGPKIETRYELGLTDRGWEYRLAAAQHEPEPDGLR
>NC_017186.1|WP_013223158.1|1334216_1335527_-|acyltransferase
MHTSRDRFLDVVRAGAILAVIAQHWIMPVLSYSDGHLATGNALATPGWWVVTWLSQVMPLVFFAGGAANLISFRRAASTQQWLAARIKRLMVPVLPLMVVWLIVPDFLRGLGVPPQPLQVGSAIAAQLLWFLAVYVLVVLLTPLMVAAHRRWGLKVPLVMGAAGLLVDVARFNDLGYLGYANAIFVWVAVHQLGFHYVEGRLGSLTRRGALTLSAAGFGITALLVAFGPYPASMIGMPGAPVSNMSPPTVLLAFLAVGQIGLLLAFRPQLNALAARPGIGDALGWLGARFMSVYLWHMPALIVVAGVTVYGLGYRTPAPGTVFWLVMAPAWFATCGMVLFGLLRLFAHFEMQRDTAVATARVPQLVAAGLLVSGGLLGLAAHGFAPLSDGIARGPVPWVVLATAGFLLAGKQIPVVDLLGRAVTVSERATLPGLKR
>NC_017186.1|WP_013223157.1|1333330_1334227_+|amidohydrolase
MTPGPADDGEVARWTASLGLPGLVDLHVHFLPKPVMDKVWAYFDRASTHYGTEWPVHYRTSEEERLATLRALGVTRFAPLVYPHKPGMAQWLTDWALEFAARVPDAVPTGTFYPEPGAGSAVDGALRAGARVFKAHVQVGAYDPRDDLLKPVWGALADAGVPVVVHCGHGPLRGDFTGLSVFEEVLARHPQLTAVLAHAAMPEFGTAFELMAKYPRVHLDTTMVGVPFAEAMSPLPPDWTARLAEFAGRVVLGTDFPNIPYSYATQLQAIAGWAADDRLGEPFLRAVLHDTPLRLLSA
>NC_017186.1|WP_013223156.1|1332851_1333334_+|SsrA-binding-protein-SmpB
MPKERGQKVIVSNRKARHDYSILDTYECGLVLVGTEVKSLREGKASLADAFATVDDGEVWLRNVHIPEYTQGTWTNHMPRRTRKLLLHRREIEKLIGKTKESGLSLVPLSMYFKDGKVKVEIALAQGKKAYDKRQTLAKRDADRDIRKAMGRALKGRFTE
>NC_017186.1|WP_013223155.1|1331911_1332805_+|ABC-transporter-permease
MRASFVFSEVVTGLRRNVTMTIAMMLTTAVSLAMLGGGLLAVRTIDKMKSNFLADVEVSVYLTDDISATDKNCTQALCQSLRTSLQSNNGVESVVFENRDQAFDRFKKIFESQPELVALTGPESLPASLHVKLKDPDRSDAIVQEYANKPGVRKVDDQKKFLDRVFNAFNGVRNMAFGAALIMAIAALLLIANTIQVSAFTRRTEVGIMRLVGATRWYTQLPFLLEAVVAGAVGAILGIIMLVLTKASFLDSVFTGDVFPKITMLELLFPVAPILLGVSVVISAITGYVTLRLYVRH
>NC_017186.1|WP_003082104.1|1331175_1331865_+|cell-division-ATP-binding-protein-FtsE
MIRLEEVSKVYKTSTRPALERVSVDIEKGEFVFLIGPSGSGKSTFLRLLLREETPSKGRVMVSNFDVAKLARRRVPRLRQTIGCVFQDFRLLANKTVAENVAFALEVIGKPGPTIKKVVPEVLELVGLDGKADRLPNELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSQDIMLLLERINRTGTTVLMATHDHSIVDSMRRRVVELQLGRVIRDDARGVYGIGR
>NC_017186.1|WP_143264264.1|1340025_1340235_+|hypothetical-protein
MTWARRSGSSLANDEDSRMGVIRAEEAVRLGEQNDRAVLTVAGHSSDVHDCAELLAMLGLDAGRRQRTA
>NC_017186.1|WP_013223164.1|1340239_1341478_-|GGDEF-domain-containing-protein
MAPRRWVLWRQGPRVIGYCLISEVVAVVLTLRPSPIAVDRRTLSILVVLLVLGVAQSETGRRVERIRRRVSGTPHINMTSVWTFAGVLLLPPLLLAVLVGGLYAHLAIRSWYRLQRVPASRTVSNAAIIVLSCYAAQSVLRLAGFSDIRSAMAHSWAGTFAIAAAGVTFFAVNAVLVLPARREVGRTPEALFGTWSDNGLEVATLCLGALNAVVLATLPGLVVLVFPPLLLLHRTVLVKQLEVAAHRDEKTGLYNTSGWHALAERTLAATARARGTFGLLMLDLDHFKQVNDTYGHLAGDAVLKAVAQSIISAVRGRGDAVGRFGGEEFVVLLPGITQPDIGAVAERIRRAISALRVPAGQLSITGLSVSIGIAVYPTAGASLQRLLDAADTALYHAKATGRNKVVHVADLV
>NC_017186.1|WP_013223165.1|1341617_1342820_-|MFS-transporter
MKKAGFGAVLAVAEFRAMWTAELLSVCGDQLARVALAVLVFQRTSSAALTALTYALTYVPSLLGGILLAGAGDRWPRRDVMVAADLARTALVAVIAVPGVPLWVLCVLVAVMTLLGGPFKAAQQALLPSVLEGERYLVGMALRNVTMQGAQLAGFAGGGALIAAFTPSAALALDAATFLLSALFLVTGVRRRAAIAQAVRPAWLSTTGAGIRLIWRDPALRTLVALNWLAGFYVVPEALAAPYAAGIGAGATLVGLLMAADPAGSVLGGVVFGKWIPEHVQVRVLGWLGIAAGLPLVVFACRPGLVVSVVLLAASGLVATGYNIQGTVSFMRRVPDAHRAQCAGVNSAGLITVQGLGAAAAGALAEVLGPAHTIAAAGAAGAAVAVPIARAWRRVGVVDR
>NC_017186.1|WP_013223166.1|1342956_1343739_-|IclR-family-transcriptional-regulator
MGDSSEVPALRRGLAVLSLLATRPGPITAAAIAREAGLPRSTTYHLLNELEAAGFVVHLPAERRYGLGIAAFELGSAYLRHDPLERLAGPLLRKLVDRVGHTAHLGVLHGNESLYLIKERPARPETLVTEVGVRLPAQLTASGRAILRHLPAAHVRALFPAAPAFVLRTGRGPRTLAELRRTLTAERRLGWSVEDGHVTDGFASVACPVFDHGARPLAAISVTLRHHCAAEPCTETWPDLAGEVAATAAELTTRIGGHPA
>NC_017186.1|WP_013223167.1|1343823_1345350_+|histidine-ammonia-lyase
MPEKVLLGPEPLTAAQVVDVVRGYAPVGLTDAAEKNLAATRLHIENLAHAVTPTYGVSTGFGALATRHIPVESRTALQRSLIRSHAAGAGPAVEPEVVRALMLLRLRTLASGYTGVRAGTAQTLAALLNADITPIVHEYGSLGCSGDLAPLAAVALALMGEGEVIHAGQLKPAAEALKQAGIEPVVLAEKEGLALTNGTDGMLGMLLLAAADLHRLFDVADLTAAMSVEALLGTDRAFAADLQALRPHPGQAKSAARMWQALQGSKIVESHRGPDCNRVQDAYSLRCAPQVHGAARDSLAHAELVGDRELMSAVDNPVVLADGRVESNGNFHGAPVAYVLDFLAIPVADVASIAERRTDRMLDKARSHGLPPFLAHDPGVDSGHMIAQYTQAAIVSELKRLAVPASVDSIPSSAMQEDHVSMGWSAARKLRKAVDGLTTVLAIELLTAARALDFRAPLEPSPVTGAVRDLLRTKVAGPGPDRHLAPEIAAAEELVRSGAVLDAARLEV
>NC_017186.1|WP_013223168.1|1345352_1347005_+|urocanate-hydratase
MSRVVRAARGTQLTAKSWQTEAALRMFHNNLDPDVAERPEDLVVYGGTGKAARNWASFDAITRELTTLDVDETLLVQSGKPVGVFRTHEWAPRVLIANSNLVGDWATWPEFRRLEQQGLTMYGQMTAGSWIYIGTQGILQGTYETFAAVAKKKFGGSLRGTLTVTAGLGGMGGAQPLAVTMNDGVAMVIECDPQRAHRRVETRYLDEVADDLDDAIARVTKAKQEKRPLSVGVVGNAAEVLPELLRRGVEVDIVTDQTSAHDPLSYLPKGVSVDDWHDYAAKKPDEFTDRSRESMADHVDAMLGFLDRGAEVFDYGNSLRGEAKLGGCERAFDFPGFVPAYIRPLFCEGNGPFRWAALSGDPEDIAATDRAMLELFPENESLARWIKLAGERVAFQGLPARICWLGYGERHLAGLRFNEMVASGELKAPVVIGRDHLDSGSVASPYRETEGMADGSDAIADWPLLNALVNTSSGASWVSIHHGGGVGMGRSIHAGQVSVADGTLLAAQKLERVLTNDPGMGVIRHVDAGYDQAADVADERGVRVPMREDA
>NC_017186.1|WP_013223169.1|1347001_1348198_+|allantoate-amidohydrolase
MTASGFLAEIAGVGRDPKRGGYSRHAFDAPEHDLREWFVERALGLGLDVETDRNGNIWAWWGPPGRNAVVTGSHLDSVPGGGAFDGPLGVVSGLSAVEALQTNGFRPRRPLAVVVFAEEEGGRFGVPCLGSRLLTGTIDADKARGLRDADGVTFAEAAGKAGVDPARMGRDTERLDRIGQFLELHVEQGRGLIDLGAPVAVGSTVIAHGRWRFSFAGQGNHAGATLLADRADPMLPAAATVTAVRRLAAQVPDARATVGRLVPTPGGTNVIASTVDLWLDARVPGQGTPGLVAEISRAASEAAQEEGCRVEVTRESYSGDVVFDDALRRDLGGWLGGPPELPTGAGHDAAILAGFVPAGMLYVRNPTGISHSPEEFAEAGDVEAGAAALATVLERLAR
>NC_017186.1|WP_071831517.1|1348194_1349550_+|formimidoylglutamate-deiminase
MTLSPRGRPPFPAYRPAPTVFWCEQAWLPGGIAAGVRIDVDGGRITGATPGSPRSGTVLTGLTLPGFANGHSHAFHRALRGRTHHERGTFWTWRERMYALASRLDPDTYYRLARGVYAEMVLGGYTSVGEFHYLHHAPGGKPYADPNAMGAALRQAAADAGIRLTLLDTCYLAGGIGVEPDEVQRRFSDGSASAWASRVSTLKEDELFRVGGAIHSVRAVPEDELSQVDDGVPGNRPLHIHLSEQRAENEQCEAATGFTPTGLLGDHGVLGERLTVVHATHLTDQDVRWLGEFRVGACFCPTTERDLGDGIGPARALRDAGVPLSIGSDSNAIVDAFEETRALELDDRLASEERGRFSAEELLEAGTHHATIGWNEVGTLAVGAGADLVTVSLDSLRTAGIEPSGVVFAASGADVRNVVVAGREVVRDGAHLLVDRPESVLAKEIEALWQS
>NC_017186.1|WP_013223171.1|1349537_1350683_+|imidazolonepropionase
MAVLITGIGELTTNDPALGRLSDAALVLDGSKVAWAGPASSAPDADERVDVEGRAVLPGWVDSHTHLVFAGDRTAEFEARMAGKPYTAGGIAITVGATREASDEQLAANLRRHVDEAARQGTTCLETKTGYGLTVADEARSARIAGKVADEVTFLGAHLVPPGADAESYVDLVCGEMLDAVAESVRWADVFCETGAFDETQSARVLKAAAERGLGLRVHGNQLGEGPGVRLAVELGAASVDHCTYLSDADLEALAAAETVATLLPACDLSTRQPLAPARRLLDAGAMVALASNANPGSSYTTSMAFCVATAVLQMRMTIEEAVWAATAGGAKALRRDDVGVLRPGARADVHVLDAPSVTHLAYRPGVPLTNLVWRAGERVR
>NC_017186.1|WP_013223172.1|1350796_1351948_+|FAD-dependent-monooxygenase
MIIIGAGLGGLSLAHGLRRAGIPCRVYERDESAGARKQGYRLHISGVGDTALREVLPPELHELFRATAGRALPHTNVYDHRLRLLTRLEGEGTHLNINRFTLRQILLHGQEVAYGKQFTHYETGADGVTAHFADGTAARGDLLVGADGINSGVRRQYLPHAQVVDAGLVHLYGRIPLTPETRALFEPEMFAVFSMMIGPDRTMAGFAPVDYPEPVAGACARLVPDLRLRDDRPYMTCSVGARWEIAGHSEAELAAMAPEDLQKVALRLVDGWHPVARAMVEHWDVPATFPQPIRTSIPIGPWEPSHVTLVGDAIHAMSPAAGAGANTALRDGAALASALAGAPPLEAVAAYETAMVDYGFAAVRESAENGRRYLGQNPLTTAG

Crispr_ID: NC_017186_5

• CRISPR_ID: NC_017186_5
• CRISPR_location: 1356881-1357109
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NC_017186_5

Consensus_repeat	Method
TCGAGAGCACTGCTCNCG	CRT

spacers of NC_017186_5

>5.1|1356899|24|NC_017186|CRT
TGCGGCGACCGGCAGTGCTCAGCT
>5.2|1356941|25|NC_017186|CRT
CGCGATGGGCGAGCGATGCTCGATA
>5.3|1356984|24|NC_017186|CRT
CATCGCGGCGCACAACGACCGGCG
>5.4|1357026|24|NC_017186|CRT
CCCGGCCCGGCGTGGTGCTCTGAA
>5.5|1357068|24|NC_017186|CRT
CGCCACTGCGAGCGATGTTCAACT

CRISPR arrays and Neighbor proteins around NC_017186_5

CRISPR arrays

The CRISPR arrays of NC_017186_5

>merge|NC_017186|5|1356881-1357109|CRT
TTGTGAGCACTGCTCTCGTGCGGCGACCGGCAGTGCTCAGCTTCGAGAGCACTGCTCTCGCGCGATGGGCGAGCGATGCTCGATATCGAGAGCACTGCTCACGCATCGCGGCGCACAACGACCGGCGTCGAGAGCACTGCTCACACCCGGCCCGGCGTGGTGCTCTGAAACAAGAGCACTGCTCACGCGCCACTGCGAGCGATGTTCAACTTCGAGAGCACCGCTCACG

>NC_017186|5|1|1356881-1357109|CRT
TTGTGAGCACTGCTCTCG	TGCGGCGACCGGCAGTGCTCAGCT
TCGAGAGCACTGCTCTCG	CGCGATGGGCGAGCGATGCTCGATA
TCGAGAGCACTGCTCACG	CATCGCGGCGCACAACGACCGGCG
TCGAGAGCACTGCTCACA	CCCGGCCCGGCGTGGTGCTCTGAA
ACAAGAGCACTGCTCACG	CGCCACTGCGAGCGATGTTCAACT
TCGAGAGCACCGCTCACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013223169.1|1347001_1348198_+|allantoate-amidohydrolase	unknown	unknown	gnl|CDD|236456
NC_017186.1|WP_013223183.1|1361378_1364375_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|366375
NC_017186.1|WP_013223171.1|1349537_1350683_+|imidazolonepropionase	unknown	unknown	gnl|CDD|237604
NC_017186.1|WP_013223188.1|1369527_1370034_+|DoxX-family-membrane-protein	unknown	unknown	gnl|CDD|284659
NC_017186.1|WP_013223187.1|1368609_1369440_-|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NC_017186.1|WP_013223184.1|1364448_1365237_-|ABC-transporter-permease	unknown	unknown	unknown
NC_017186.1|WP_013223177.1|1355828_1356575_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223180.1|1358777_1359452_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017186.1|WP_013223178.1|1356571_1356781_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_014466649.1|1354489_1355617_+|inorganic-phosphate-transporter	unknown	unknown	gnl|CDD|376541
NC_017186.1|WP_071831517.1|1348194_1349550_+|formimidoylglutamate-deiminase	unknown	unknown	gnl|CDD|236420
NC_017186.1|WP_013223176.1|1355625_1355847_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223173.1|1351931_1352795_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|334634
NC_017186.1|WP_013223174.1|1352876_1354295_-|apolipoprotein-N-acyltransferase	unknown	unknown	gnl|CDD|234721
NC_017186.1|WP_013223186.1|1366219_1368613_-|ATP-dependent-helicase-HrpB	unknown	unknown	gnl|CDD|273901
NC_017186.1|WP_013223179.1|1357206_1358781_+|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_017186.1|WP_013223172.1|1350796_1351948_+|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|223727
NC_017186.1|WP_013223185.1|1365233_1366148_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213235
NC_017186.1|WP_013223181.1|1359396_1360521_-|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|168661
NC_017186.1|WP_013223182.1|1360473_1361127_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380066

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013223169.1|1347001_1348198_+|allantoate-amidohydrolase	gnl|CDD|236456	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed.	2.24909e-161
NC_017186.1|WP_013223183.1|1361378_1364375_+|tetratricopeptide-repeat-protein	gnl|CDD|366375	pfam00931, NB-ARC, NB-ARC domain.	7.62847e-11
NC_017186.1|WP_013223171.1|1349537_1350683_+|imidazolonepropionase	gnl|CDD|237604	PRK14085, PRK14085, imidazolonepropionase; Provisional.	0
NC_017186.1|WP_013223188.1|1369527_1370034_+|DoxX-family-membrane-protein	gnl|CDD|284659	pfam07291, MauE, Methylamine utilisation protein MauE. This family consists of several bacterial methylamine utilisation MauE proteins. Synthesis of enzymes involved in methylamine oxidation via methylamine dehydrogenase (MADH) is encoded by genes present in the mau cluster. MauE and MauD are specifically involved in the processing, transport, and/or maturation of the beta-subunit and that the absence of each of these proteins leads to production of a non-functional beta-subunit which becomes rapidly degraded.	3.30951e-08
NC_017186.1|WP_013223187.1|1368609_1369440_-|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.23502e-90
NC_017186.1|WP_013223180.1|1358777_1359452_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.31973e-69
NC_017186.1|WP_014466649.1|1354489_1355617_+|inorganic-phosphate-transporter	gnl|CDD|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	2.21284e-92
NC_017186.1|WP_071831517.1|1348194_1349550_+|formimidoylglutamate-deiminase	gnl|CDD|236420	PRK09229, PRK09229, N-formimino-L-glutamate deiminase; Validated.	4.92182e-178
NC_017186.1|WP_013223173.1|1351931_1352795_-|alpha/beta-hydrolase	gnl|CDD|334634	pfam01674, Lipase_2, Lipase (class 2). This family consists of hypothetical C. elegans proteins and lipases. Lipases or triacylglycerol acylhydrolases hydrolyze ester bonds in triacylglycerol giving diacylglycerol, monoacylglycerol, glycerol and free fatty acids. Lipase EstA is a extracellular lipase from B. subtilis 168.	4.11304e-19
NC_017186.1|WP_013223174.1|1352876_1354295_-|apolipoprotein-N-acyltransferase	gnl|CDD|234721	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed.	2.29099e-21
NC_017186.1|WP_013223186.1|1366219_1368613_-|ATP-dependent-helicase-HrpB	gnl|CDD|273901	TIGR01970, ATP-dependent_RNA_helicase_HrpB, ATP-dependent helicase HrpB. This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity].	0
NC_017186.1|WP_013223179.1|1357206_1358781_+|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	7.13332e-29
NC_017186.1|WP_013223172.1|1350796_1351948_+|FAD-dependent-monooxygenase	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	2.56718e-29
NC_017186.1|WP_013223185.1|1365233_1366148_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	3.23584e-88
NC_017186.1|WP_013223181.1|1359396_1360521_-|FAD-dependent-monooxygenase	gnl|CDD|168661	PRK06753, PRK06753, hypothetical protein; Provisional.	1.90809e-79
NC_017186.1|WP_013223182.1|1360473_1361127_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|380066	pfam17940, TetR_C_31, Tetracyclin repressor-like, C-terminal domain. This is the C-terminal domain found in putative transcriptional regulator, TetR family proteins.	4.82358e-16

Protein sequences

>NC_017186.1|WP_013223178.1|1356571_1356781_-|hypothetical-protein
MAERTLADQLGGYLPEGIEALEEHERQDLADALRDARRRQAKALAEAGEEGLLYVPALLRGAVRKAVGL
>NC_017186.1|WP_013223177.1|1355828_1356575_-|hypothetical-protein
MTENYAAEAEILKLARVLDVEPARLAYLGRVDADDLQAFRGQVTDTLFDANAAALQRMALAARVVPVGVLAKIAEKVFGPLLCARIAGLVDVGRGVDVAKRLSPRFLADVAAELDPRRASAIISRIPLDTVLAVAGELAHKEDWITLGRFVGHLPDPTVQQALNRIDDPSLLRIAFVLDDKRRVDHVVGLLPAHRLGRLVTAASADEDLWTPALDLLTHLGEARRATLKPMLADLPEGFRDRVQATIK
>NC_017186.1|WP_013223176.1|1355625_1355847_+|hypothetical-protein
MHINWGSLGLVFVVALASVVVLTSLFSFGVVGLSQRESAREAGGSGSGPLAGAVVCFAACLAIIGYGIYLIVA
>NC_017186.1|WP_014466649.1|1354489_1355617_+|inorganic-phosphate-transporter
MDFSLIVLVVIVAALAFDFTNGFHDTANAMATSIATGALKPRVAVAVSAVLNLVGAFLSVEVAKTISGGIVDDTKVTPVIIFAGLVGAIVWNLVTWLIGLPSSSSHALFGGLIGATWIASGSDAVHFGKVVEKILIPALASPIVAGIVATLGTFLVYRITARAKQDTVGRTFKAGQIASASLVSLAHGTNDAQKTMGVITLTLIASGSLAPNSSPPVWVILTAGTAIALGTYLGGWRIIQTMGKKLTEIQTPQGFAAETSAAAVILTSAHLGFALSTTHVCSGGIIGSGLGRKLAEVRWGVAGRMVLAWALTLPAAAIVGALAAEVSTLGTWGTVLVGLAGVVIALGIYLASKRNPVNANSINEPEPGVTQPANA
>NC_017186.1|WP_013223174.1|1352876_1354295_-|apolipoprotein-N-acyltransferase
MNKLGWALVATVASAVLFFFGTGLDPVPELAWLAPLPVLLLAPRVPGAAAMACAFVAYLAGSAGSWSYFWHSLSIPRPAAIGILGGSALLFALSAGLFRVLVRRGHGLPAALAAPALWTVVLYVVSLLNPTGVMDTLMTTQADRPSVLRLATVTGGWGVEFLVLFVPAAVAAALAPGVRARARLSGLVVTAAVLAGLVFWTTPPLTGPPTRIALLAMGQSRWALDVATFEGRTRIQSYVDEIGRLPEGVQAVVLPEATFAVDEASRPRLVEAFTQVARAKNLDVVTGVIDTTPDGRFNAALAIPPSGPPVEYRKWHNGDSPNLGSGTRTAHLAGIGLMVCMDVNFADPSGEYGEAGTGLVLIPASDEDVDGWAHSRTALIRGVENGFSVAWSAARGTPMLADARGHVLAETHTGDRPFSVVVADVPLGPGKTPYARFGDWFAWLCGLVALAGIGTAARRPSLSPVTTNAGQL
>NC_017186.1|WP_013223173.1|1351931_1352795_-|alpha/beta-hydrolase
MRVTNGGAKRILAVLAAALTFGALAPSVAEAAPSSGWNDWGCRPSAAHPEPVVLVHGLGANDTVNWFFHAPKIAAQGYCVFSLTYGTGVLGPGVGGLASMRDSAAQLGRFVDRVRSTTGAAKVDIVGHSEGSTMPAYYLKYGGAAKVARFVGFGANYRGTTLGGLDALAKALLTSVPELGAVLRTACGACTEYLAPSAFLDDLARGGVHVPGPTYTSIVSKYDEVVTPYTSGILGEPGTTDIVLQDFCAGDASGHLSQAADPNVTGLILHALDAGYAPTCTPFTLPL
>NC_017186.1|WP_013223172.1|1350796_1351948_+|FAD-dependent-monooxygenase
MIIIGAGLGGLSLAHGLRRAGIPCRVYERDESAGARKQGYRLHISGVGDTALREVLPPELHELFRATAGRALPHTNVYDHRLRLLTRLEGEGTHLNINRFTLRQILLHGQEVAYGKQFTHYETGADGVTAHFADGTAARGDLLVGADGINSGVRRQYLPHAQVVDAGLVHLYGRIPLTPETRALFEPEMFAVFSMMIGPDRTMAGFAPVDYPEPVAGACARLVPDLRLRDDRPYMTCSVGARWEIAGHSEAELAAMAPEDLQKVALRLVDGWHPVARAMVEHWDVPATFPQPIRTSIPIGPWEPSHVTLVGDAIHAMSPAAGAGANTALRDGAALASALAGAPPLEAVAAYETAMVDYGFAAVRESAENGRRYLGQNPLTTAG
>NC_017186.1|WP_013223171.1|1349537_1350683_+|imidazolonepropionase
MAVLITGIGELTTNDPALGRLSDAALVLDGSKVAWAGPASSAPDADERVDVEGRAVLPGWVDSHTHLVFAGDRTAEFEARMAGKPYTAGGIAITVGATREASDEQLAANLRRHVDEAARQGTTCLETKTGYGLTVADEARSARIAGKVADEVTFLGAHLVPPGADAESYVDLVCGEMLDAVAESVRWADVFCETGAFDETQSARVLKAAAERGLGLRVHGNQLGEGPGVRLAVELGAASVDHCTYLSDADLEALAAAETVATLLPACDLSTRQPLAPARRLLDAGAMVALASNANPGSSYTTSMAFCVATAVLQMRMTIEEAVWAATAGGAKALRRDDVGVLRPGARADVHVLDAPSVTHLAYRPGVPLTNLVWRAGERVR
>NC_017186.1|WP_071831517.1|1348194_1349550_+|formimidoylglutamate-deiminase
MTLSPRGRPPFPAYRPAPTVFWCEQAWLPGGIAAGVRIDVDGGRITGATPGSPRSGTVLTGLTLPGFANGHSHAFHRALRGRTHHERGTFWTWRERMYALASRLDPDTYYRLARGVYAEMVLGGYTSVGEFHYLHHAPGGKPYADPNAMGAALRQAAADAGIRLTLLDTCYLAGGIGVEPDEVQRRFSDGSASAWASRVSTLKEDELFRVGGAIHSVRAVPEDELSQVDDGVPGNRPLHIHLSEQRAENEQCEAATGFTPTGLLGDHGVLGERLTVVHATHLTDQDVRWLGEFRVGACFCPTTERDLGDGIGPARALRDAGVPLSIGSDSNAIVDAFEETRALELDDRLASEERGRFSAEELLEAGTHHATIGWNEVGTLAVGAGADLVTVSLDSLRTAGIEPSGVVFAASGADVRNVVVAGREVVRDGAHLLVDRPESVLAKEIEALWQS
>NC_017186.1|WP_013223169.1|1347001_1348198_+|allantoate-amidohydrolase
MTASGFLAEIAGVGRDPKRGGYSRHAFDAPEHDLREWFVERALGLGLDVETDRNGNIWAWWGPPGRNAVVTGSHLDSVPGGGAFDGPLGVVSGLSAVEALQTNGFRPRRPLAVVVFAEEEGGRFGVPCLGSRLLTGTIDADKARGLRDADGVTFAEAAGKAGVDPARMGRDTERLDRIGQFLELHVEQGRGLIDLGAPVAVGSTVIAHGRWRFSFAGQGNHAGATLLADRADPMLPAAATVTAVRRLAAQVPDARATVGRLVPTPGGTNVIASTVDLWLDARVPGQGTPGLVAEISRAASEAAQEEGCRVEVTRESYSGDVVFDDALRRDLGGWLGGPPELPTGAGHDAAILAGFVPAGMLYVRNPTGISHSPEEFAEAGDVEAGAAALATVLERLAR
>NC_017186.1|WP_013223179.1|1357206_1358781_+|two-component-sensor-histidine-kinase
MRTVTKRRWQTALDVAVGLFLAFIVVAGTLESRSYGELAGGLVVVAGSVATARRYPAVSLGIALSGALAVPFPYGNRVPAWVIFVLVAMSYQAGLRMPRARPGVLTGTAVAVVGLPVALVFGTDGLGDWAELVAILVFAGLSPWLLGRYVRVRGELARTGWRRAEEMESRQQLVAEQARLRERARIASDMHDSLGHELSLIAVRAAALEVAGGLGDAQRDAAAQLRTSAATATERLREIIGVLREDAAPVEPVQGDLGALIARARASGLLIESTVDVAEVPPMVARAAYRVVQEALTNVAKHAPGAAVTVRVTSAGARTDVSVVNAPPPAGPLPGTASGHVGLIGLRERVRLVGGTLRAGPDAGGFAVTATLPHGAAPVERPETAPADEEAGLSTSARALELARRDVRRSLIQAVTVPLVLFGLVLAVAGIAFLYQWNSSELSTGVYERLRIGQPRTDVAPQLPENQRDARPLRSEPPRPAVPGVACEYYGTGRSWLDNDYAAYRLCFADGMLVAKDWFAEGAP
>NC_017186.1|WP_013223180.1|1358777_1359452_+|response-regulator-transcription-factor
MIKVVLADDEAMMRAGVAAILAADPGIEVVAEAADGRSAVSQVLATRPDVVLLDIRMPGLDGLGAAAEIRRLLPATGVIMLTTFGEDEYIERALGLGAGGFLLKSGDPRELLSGIHAVAGGAAFLSPKVAQRVIARLSGGQLARAAAARERIAALTPREREVLTLLGSGLSNADIAAKMFVVEGTVKAHVSTILNRLGAKNRVQAAITAYEAGLVGGDAAASTP
>NC_017186.1|WP_013223181.1|1359396_1360521_-|FAD-dependent-monooxygenase
MVGGGIGGLAAAAGLHRVGWTVTVLEKAPEFGDVGAGISLWPNALRSLDELGVDLGRRLAPQQEGRFRDRRGRRISHFDATEFARWHGRPLGAIHRRDLIAALRDAVPAESLCTGQEVTEVREDGLVRVGSKELRADLVVAADGIHSRVRHTLFPDHPEPVYTGSTAFRGVAHRPGTGLSTSFDRGTEVGVLPLTGGDVYWWISTLAAPGTRRADLEQTFGNWHDPIPALLAATPPEAVLHHDLYYLGTPLPAYTRGQIALLGDAAHAMSPFLGQGGCQAIEDAVVLAHAVSTQDTVDAALVRYDRQRRPRSQHVVRESVRMGKLGPQLTNPVAVGLRTALLKCLPAKATARAGAGITGWTPPRLRRPVPPRTP
>NC_017186.1|WP_013223182.1|1360473_1361127_+|TetR/AcrR-family-transcriptional-regulator
MQPRGRRQAADASADHYCVHVASSTFVEDSTPVECIFVERVDVIADAAIGVIAAEGMRGLTHRAVDRAAGLPVGSTSYYARTRAALLELTIARIVVLDQAPTGASGSLAEFIAGYAFEAITSGRTRMLARYEFALEATRRPELRAVYDEGGLQIRRQAAAALEAAGSADPSRHARVVVDWMEGTIFGALAGTGSLAPPDLDELVASAREILTGIGVA
>NC_017186.1|WP_013223183.1|1361378_1364375_+|tetratricopeptide-repeat-protein
MEHSRQVVHRTILAVDIESYGALRRTTPHRLTVRRGLDQALRRAFDEAGVPWFDCRHESTGDGTFVLVPAQVPKSPFVEVLSMVLARELRRHNEAHQPEEQIRLRMALHAGEVAYDDQGVTGSAINRTFRLLEAPQLKAALAESPGVLALITSDWFFDEVVRSSTVVDAATFRPVRVAVKETIATGWISLPDHFCAPHPELGIPTPPRQPATVDAHGPVIGQCTLPRDLPVFTGRAKELDILAATVTAEAEKGTLGMAIHVIDGMPGTGKTTFAVHAAYQLAAHFPDGQIFLELHGHSPSQVPVTPADALASLLFLRGVSTLGIPADLDDRARLWREKLTGKKILLLLDDAVDGEQIQPLLPGGAGCLVLITSRHRFESIADAGRVSLQTLPAAEAAAMFDRFTSPEQHEPGAVAELMTLCGNLPLAISLTAGRLRSHPSWTLRQLADDLNHSQNRLKTLRADNRSVAAAFELSYRDLDPDQQRLFRRLSLHPGSHIDAAAAAALDGNDVDATRERLEVLYLNNLLDEPSPGRYRLHDLTQAYSQSLTDPKTDKGAFERLLDYYLETVRAASQFAASPSPRLDLGPRLPMPTRKFDTEGEAIAWLTAERPTIGACINAAAASNRVRRAAELAAALYPFLEQHGYWHDAYRLQRAVLTAAQEAGDLVVEAATRADLGRVLRLLGNYHDAAATLACARDLYLELGNRLGEADVLNEAGRVQQEVSNFIGATAYLDRAHQLYEELHNPLGVAATFAQLARVQYRSCDLEAARTNAERSLDLYRLLGNEPGEMSALLTVGCAQGMSGAYACAVAAFTQALSLSRKLGDRFAEARALNNLGRMHFDCGNYGTADSYYSRAQIIYSQLDYRARVAVTLTNLGRLHHAAGNHRLAFTYMTRAADLFGDDQGWHSENLNNLGSLALEWPDAGDPAELHGRALDLARAVGVRLQVGRALEGLGRSALKAADGARGIEYLRQALALYRELAVPEAAAVRATLDELANM
>NC_017186.1|WP_013223184.1|1364448_1365237_-|ABC-transporter-permease
MTASVEIRGGGLPGAVAAEWTKFWSVRATWWCLVTGAALMLGYGTLSAITQRIGGDEPQAAPTIALGGGFYLAQFAVIALATLAVTSEYAGGGIRSTLLWTPVRPRVVLAKAAVLAPALFVYGVLLSCAGMALATAVMNGHGLPTSPEAAFTTASGMGGYFALLGLLCAGIGWALRSTAGTLVSVIVLLVPLPLIVASLGLPEAMPYFPGIAGVNAMVEAGKPNPITMTAAPYAPWVGLAICAAWAAAALLAGAAVLRRRDA
>NC_017186.1|WP_013223185.1|1365233_1366148_-|ATP-binding-cassette-domain-containing-protein
MITLRGLTKRYGEKTVVDALTCDIAAGQVTGFLGPNGAGKSTTMRMTVGLDHPQAGEALVGGRRYAELRHPLREVGALLDAKALHPGRSAGKHLLAMARSNGIAASRVEEVLATVGLSDVAGKRAGQFSLGMGQRLGIAGALLGDPGVLLFDEPVNGLDPDGVRWVRQLMRSLAAEGRTVFVSSHLMSEMQLTADHLVVIGKGRLLADAPVAEFIAGHSRTTVSVRIPADGDRSILDARLRAEGGLTRQGEPGELVVDGIHVTRAGDLVHELGIRVHGLAERTASLEQAYMELTASSVEYGVSA
>NC_017186.1|WP_013223186.1|1366219_1368613_-|ATP-dependent-helicase-HrpB
MKLPDLPVRSVLPDVVAALDERGAAVLVAPPGTGKTTLVPLALAAAAEGRVVVAEPRRLAARAAAARMAALLGEPVGETVGYAVRGDRKVSARTRIEVVTSGLLVRRVQGDPELPGVSTVLLDECHERHLDADLLLALLLDVRAGLREDLRLLATSATVASGRLAALLGDAPVVTATARTYPVEFSYLPPARGERVEVCVARAVRTALSEGDGDVLAFLPGAGEIARTAGLLRLSDVDVLPLHGRLSAAHQDDALRPRDRRRVVLATAVAESSLTVPGVRAVVDSGLARVPRVDHRRGLPGLATVRVSAAVATQRSGRAGREAPGRAYRCWAEHEQATLPAYPEPEIRTAELARLALELACWSTPDGSGLAWWDPPGEGALAAGRALLVTLGATSPDGTVTQRGRRMAELGLHPRLARALLDGSSEVGARNAAEVVALLDAGATLTDVHAELRRLRSATDEGARRWKREARRLEGLVPERRAERPAPADPALVVALAHPERLAKRRPGDAPVYLMAGGTAAELPPGSGLDAEWLAIAEATRDPGRVHGTIRLAAAADETLAVRTGAVSEVDEVTWDGDVVARRVRKLGAIVLSEKPLKNADVRGALVAGLKSEGLGLLKWSQDATRLRERMAFLHRVLGPPWPPVDDAALLSDVDSWLDLGTARRKADLANINAGTALKALLPWPEAAKLDDLAPDRLEVPSGSHIRVDYRGDQPVLAVKLQETFGWTETPVIAGVPVVLHLLSPAGRPAAITADLASFWTSGYPAVRADLRGRYPKHPWPEDPAGAVPTRHTRRRS
>NC_017186.1|WP_013223187.1|1368609_1369440_-|glutamate-ABC-transporter-substrate-binding-protein
MRWRTLLGSVLLLVTASACGPAKVSPTDSLVTRASATDHLTIGIRFDAPGLSEHTVDGRFVGFDVDVATFVASELGVSAKDITWRETTSATRETDLTSGAVDLVVASYSITDKRKQVVSFAGPYFTTGQDLLVRRTSADIAGPEALNGRRLCSVTGSTPAQQVKDKYAQAVQLVEYPRYSDCVTALLAGQIDAVTTDAVILAGYVARDPELLKIVGKPFSKESYGVGLRKDDTQGVAAVDDAIRKMISSGEWLRSLNANIGPSGYQLPPPPEVTQK
>NC_017186.1|WP_013223188.1|1369527_1370034_+|DoxX-family-membrane-protein
MLNTVGTLARLGLAAVWLVSGALKLADPGQTLIAVQAYQVLPDALENVVAIALPLVELVLGLLLLAGLATRWAAAAALGLLLVLIAGIAQSWARGLSIDCGCFGGGGQVAAGQTEYPQEILRDTGFALLAGWLLARPRTWLSLDGWLGRGRGNSGEPGHDYSGIAEGN

Crispr_ID: NC_017186_6

• CRISPR_ID: NC_017186_6
• CRISPR_location: 1632660-1632783
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_6

Consensus_repeat	Method
GCCGTGGCGGAGCCGAGCTGCCGCGGTGG	CRISPRCasFinder

spacers of NC_017186_6

>6.1|1632689|66|NC_017186|CRISPRCasFinder
AGCCGAGTCGGCCGTGGCGGAGCCGAGCTGCCGCGGTGGAGCCGAGTCGGTTGTGGAGCCGAGTCG

CRISPR arrays and Neighbor proteins around NC_017186_6

CRISPR arrays

The CRISPR arrays of NC_017186_6

>merge|NC_017186|6|1632660-1632783|CRISPRCasFinder
GCGGCGGTCGAGCGGAGTTGCCGCGGTGGAGCCGAGTCGGCCGTGGCGGAGCCGAGCTGCCGCGGTGGAGCCGAGTCGGTTGTGGAGCCGAGTCGGCCGCGGTGGGGCCGAGCTGCCGTGGCGG

>NC_017186|6|5|1632660-1632783|CRISPRCasFinder
GCGGCGGTCGAGCGGAGTTGCCGCGGTGG	AGCCGAGTCGGCCGTGGCGGAGCCGAGCTGCCGCGGTGGAGCCGAGTCGGTTGTGGAGCCGAGTCG
GCCGCGGTGGGGCCGAGCTGCCGTGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013223425.1|1631079_1632303_-|hypothetical-protein	unknown	unknown	gnl|CDD|227324
NC_017186.1|WP_013223429.1|1638448_1639930_+|glycoside-hydrolase	unknown	unknown	gnl|CDD|227721
NC_017186.1|WP_013223420.1|1625766_1626534_+|DUF4239-domain-containing-protein	unknown	unknown	gnl|CDD|372881
NC_017186.1|WP_013223430.1|1640106_1641294_-|glycoside-hydrolase-family-88-protein	unknown	unknown	gnl|CDD|226678
NC_017186.1|WP_013223421.1|1626530_1627838_+|hypothetical-protein	unknown	unknown	gnl|CDD|237864
NC_017186.1|WP_013223436.1|1649900_1651274_+|cytosine-permease	unknown	unknown	gnl|CDD|224374
NC_017186.1|WP_013223434.1|1646208_1648140_+|S8/S53-family-peptidase	unknown	unknown	gnl|CDD|173788
NC_017186.1|WP_013223428.1|1636560_1638132_+|alkaline-phosphatase-D-family-protein	unknown	unknown	gnl|CDD|226070
NC_017186.1|WP_176742142.1|1627844_1628861_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380525
NC_017186.1|WP_013223433.1|1644750_1645905_+|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NC_017186.1|WP_014466680.1|1629121_1629577_+|DUF4396-domain-containing-protein	unknown	unknown	gnl|CDD|379568
NC_017186.1|WP_013223416.1|1620159_1621302_+|CapA-family-protein	unknown	unknown	gnl|CDD|378215
NC_017186.1|WP_013223417.1|1621464_1622484_-|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|223220
NC_017186.1|WP_013223431.1|1641646_1643419_+|alpha-L-fucosidase	unknown	unknown	gnl|CDD|376461
NC_017186.1|WP_034284436.1|1635872_1636529_+|hypothetical-protein	unknown	unknown	gnl|CDD|227324
NC_017186.1|WP_013223419.1|1623871_1625341_-|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|237999
NC_017186.1|WP_013223418.1|1622483_1623875_-|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|237999
NC_017186.1|WP_013223435.1|1648230_1649766_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NC_017186.1|WP_013223424.1|1629614_1630862_-|glycoside-hydrolase-family-88-protein	unknown	unknown	gnl|CDD|369381
NC_017186.1|WP_013223432.1|1643459_1644689_-|hypothetical-protein	unknown	unknown	gnl|CDD|236653

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013223425.1|1631079_1632303_-|hypothetical-protein	gnl|CDD|227324	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown].	8.25356e-05
NC_017186.1|WP_013223429.1|1638448_1639930_+|glycoside-hydrolase	gnl|CDD|227721	COG5434, PGU1, Endopygalactorunase [Cell envelope biogenesis, outer membrane].	1.17868e-29
NC_017186.1|WP_013223420.1|1625766_1626534_+|DUF4239-domain-containing-protein	gnl|CDD|372881	pfam14023, DUF4239, Protein of unknown function (DUF4239). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 254 and 270 amino acids in length.	3.0439e-06
NC_017186.1|WP_013223430.1|1640106_1641294_-|glycoside-hydrolase-family-88-protein	gnl|CDD|226678	COG4225, COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only].	9.85077e-80
NC_017186.1|WP_013223421.1|1626530_1627838_+|hypothetical-protein	gnl|CDD|237864	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional.	4.54658e-11
NC_017186.1|WP_013223436.1|1649900_1651274_+|cytosine-permease	gnl|CDD|224374	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism].	2.13201e-59
NC_017186.1|WP_013223434.1|1646208_1648140_+|S8/S53-family-peptidase	gnl|CDD|173788	cd04056, Peptidases_S53, Peptidase domain in the S53 family. Members of the peptidases S53 (sedolisin) family include endopeptidases and exopeptidases sedolisin, kumamolysin, and (PSCP) Pepstatin-insensitive Carboxyl Proteinase. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of Asn in subtilisin. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values. Characterized sedolisins include Kumamolisin, an extracellular calcium-dependent thermostable endopeptidase from Bacillus. The enzyme is synthesized with a 188 amino acid N-terminal preprotein region which is cleaved after the extraction into the extracellular space with low pH. One kumamolysin paralog, kumamolisin-As, is believed to be a collagenase. TPP1 is a serine protease that functions as a tripeptidyl exopeptidase as well as an endopeptidase. Less is known about PSCP from Pseudomonas which is thought to be an aspartic proteinase.	5.17564e-77
NC_017186.1|WP_013223428.1|1636560_1638132_+|alkaline-phosphatase-D-family-protein	gnl|CDD|226070	COG3540, PhoD, Phosphodiesterase/alkaline phosphatase D [Inorganic ion transport and metabolism].	8.39339e-143
NC_017186.1|WP_176742142.1|1627844_1628861_-|substrate-binding-domain-containing-protein	gnl|CDD|380525	cd06302, PBP1_LsrB_Quorum_Sensing-like, periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs. Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs from other bacteria. The members of this group are homologous to a family of periplasmic pentose/hexose sugar-binding proteins that function as the primary receptors for chemotaxis and transporters of many sugar based solutes in bacteria and archaea and that are a member of the type 1 periplasmic binding protein superfamily. LsrB, which is part of the ABC transporter complex LsrABCD, binds a chemically distinct form of the AI-2 signal that lacks boron, in contrast to the Vibrio harveyi AI-2 signaling molecule that has an unusual furanosyl borate diester. Hence, many bacteria coordinate their gene expression according to the local density of their population by producing species specific AI-2. This process of quorum sensing allows LsrB to function as a periplasmic AI-2 binding protein in interspecies signaling.	2.86913e-111
NC_017186.1|WP_013223433.1|1644750_1645905_+|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	6.77197e-49
NC_017186.1|WP_014466680.1|1629121_1629577_+|DUF4396-domain-containing-protein	gnl|CDD|379568	pfam14342, DUF4396, Domain of unknown function (DUF4396). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 167 and 310 amino acids in length.	4.39742e-38
NC_017186.1|WP_013223416.1|1620159_1621302_+|CapA-family-protein	gnl|CDD|378215	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap. This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein.	9.82252e-89
NC_017186.1|WP_013223417.1|1621464_1622484_-|polyprenyl-synthetase-family-protein	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.98561e-77
NC_017186.1|WP_013223431.1|1641646_1643419_+|alpha-L-fucosidase	gnl|CDD|376461	pfam01120, Alpha_L_fucos, Alpha-L-fucosidase.	6.30929e-15
NC_017186.1|WP_034284436.1|1635872_1636529_+|hypothetical-protein	gnl|CDD|227324	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown].	1.2139e-06
NC_017186.1|WP_013223419.1|1623871_1625341_-|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	2.67099e-19
NC_017186.1|WP_013223418.1|1622483_1623875_-|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	5.50555e-18
NC_017186.1|WP_013223435.1|1648230_1649766_-|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.31163e-39
NC_017186.1|WP_013223424.1|1629614_1630862_-|glycoside-hydrolase-family-88-protein	gnl|CDD|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	3.88756e-13
NC_017186.1|WP_013223432.1|1643459_1644689_-|hypothetical-protein	gnl|CDD|236653	PRK10137, PRK10137, alpha-glucosidase; Provisional.	8.82593e-19

Protein sequences

>NC_017186.1|WP_013223425.1|1631079_1632303_-|hypothetical-protein
MIRIMKAGRVTAAVLAAGAVTALAGAPAQAATTPSNTNWTADLSTVDSNDVNVTGAGGTLTLTDAAWHRTERVFAGSEGSLTTAEHRLGSAANRVSAELTADTPKGTSVDVDVRGRTGVNDWTEWTPAGTALKSAVSEVQVRISLHSTADGVRPSVKSVALSADSVPQVNALAAATALTYKVFGTREGLTGQTTANGHVITSRDHFVALPSGRALAGKGSGTYTVRVCKTDGSRCEYAPVWDVGPWNTKDDYWNPASVRAEYKDLPQGQPEAYAAYHNGYNGGKDDLGYKVGNPAGIDLADGVFYDGLGMSDNGNVNVTYLWTGSDKTGVVSTAGDPMNVRASASTSAAIKGLAANYAKVNIECYVEGDTVAGKFGTTNIWDRIGPNNYVSDTYLQTGSDDPVAPHC
>NC_017186.1|WP_013223424.1|1629614_1630862_-|glycoside-hydrolase-family-88-protein
MSVSRRTLLTTAAGAAVAVGASTSTAAAAGTVAATPDHPDLASATRTLRQAADYAVAKLRAVAPGVTAFPVGTKFEKWTYSQNGDWVGGFWPGQLWLAWLHSGEEQFKTLALASAEKLAPRQNDTGTHDLGFLFSPSWVTAWRLTGDEKWKAGAVQAASSLIKRYNPAGRFIRAWGALSDPNNAGRVIMDTMMNLDLLAFASAQTGDPKYLEIAAAHAKTAQQHFPRPDGSTPHVFDFDPVTGAPIGPNTVQGYSPTSCWSRGQAWGVYGFTTIHRRTGDPEFLTTARRLADFALSQLTPDHVPVWDYLAPQAPDDVKDASAGVIMACGLLDLAELTHRPHYRESALRILTAVSRTCLTTKSTRAEASVARCTRNRPNEDGVEVSLPYADYYLLEGILRVLDRRKVDRAIDLSSV
>NC_017186.1|WP_014466680.1|1629121_1629577_+|DUF4396-domain-containing-protein
MSEQHGASWATAIQATLHCLTGCAIGEVLGMVLGTAFGLHNAATVVLSIVLAFVFGYGLTMRGVLKSGLGAAAAFKVALAADTVSIAVMELIDNTVVVAIPGAMNAGLAGFLFWLSLALSLAIAFVVTVPVNKWMIGRGLGHAKVHAHHQH
>NC_017186.1|WP_176742142.1|1627844_1628861_-|substrate-binding-domain-containing-protein
MRGPTKTFRLVATVPLVAALTLGGCSDQLGSAPAPSPTRVEFVPKVRGIPYFEAMDNGGLEAAKQLGLAWHSTGPATVDPAAQVTIMRDLIAKKVDVIVVAPNDPAALAGVIAEARAKGIHVLTSDTDAPGTQREVFVNQASAQGIGTALVDALMAKTGGTGQYAIVSCGPAAANLNSWIAVQKEYAAAHYPKAELVDTVYAGEDVEAATALAKQLMAGHPGLTGLIGECTTSAPGVAKAVDDEQKIGRVFTVGVGTPQAIKPFLLKGACSQSVLWNVESLGYLTAWTAKQVVDGKPLGPVNKVSLELPAVKYDAAAKTVLLGDPLLITADNVDQFKY
>NC_017186.1|WP_013223421.1|1626530_1627838_+|hypothetical-protein
MTGTRIRWAAAFGVAAAVSALLAASGWLAPPASHLTVAREPAGCTILQAENERSGAPTTLRLLSLPGGVTRRVSQAGYWINAMGYSAAQNVVYGVADGTRAGRYHGAHAVRIDAAGVVTDLGVIGRAGAPKPVWSPVTGATAGAVDGARWYVRQGSDLYTVDIDPAGADYLRVVHRTSLRPVSLAIGVDDFAVDPADGLLYGVSATSRGDSSVVTLDPASGKVAVVPGLRFPEGGAYGSVVLAPGAIYATANQAGRRSATFRLPRDGSGPATEVATGPPLVSGDAAGCLAEPPARPPTTSPPPTTPPGQSSPPPTTPPGQSSEPPPPRTETPSPEPSPEPPPPPPPVEQPVVLPPAPVPAPTPPAVVTPPPSTPAPSPPPPAPPTTHHARPEEKTEPVAQDTGRRRTQEKRRWGLTALILVLGGGAAAAHGRRHR
>NC_017186.1|WP_013223420.1|1625766_1626534_+|DUF4239-domain-containing-protein
MNIFVAGSLWVAGAACVGGLIAYLVRRFGRDDEGRPGNNDAAGQVFTIVGGLHAVLVAFVLISLYDSVSTVSQTAQSEADSLVAASWAADALPEATKDRVHQLAAAYARTVEEQEWPRLADGGEVPATGASQLDQMRQAVAEAPADDDWLLDRKTEASNQLWSVYQARQQRLAHSGAGGVGAVVWFALILGSLITAILLPNLFGGTRLAAHIVIVSTLAGTITLLLFAIYQLQNPFSGGVSVPPEAFTSALARLV
>NC_017186.1|WP_013223419.1|1623871_1625341_-|cyclic-nucleotide-binding-domain-containing-protein
MTGVPAGTPHVPNANDWVVLVVTVTDPVESEQAPSSLGRAAARTLATTTKSVPQMQGISSRWLLKLLPWVDVAAGAYRVNRRLSYAVGDGRVTFTTTGAHVRVIPPELGELAPLRGYDDQDVLTELADRFTQHEYAPGDALVEFGSPADQVFLLAHGKITKIGTGAYGDQVVLGTLADGDHFGETTLTHDDGIWEFTAKAVTTCTVLTLPRTTFNDILTRSTTLQTHLDNYRTRGTTASNDHGEAEISLASGHDGEPQLPGTFVDYEARPREYELSVAQTVLRVHSRVADLYNQPMNQIEQQLRLTVEALRERQEHELINNTDFGLLHNTDFAQRIPTRTGPPTPDDLDQLLTLVWKDPSFFLAHPTTIAAFGRECTKAGLYPTSVDLAGHQVPSWRGIPLLPCNKIPVTDTRTSSILLMRTGEQAQGVVGLHQTGLPDEYQPGLNVRFMGINDQAIISYLVSAYYSAAVLVPDALAVLENAEIGRETP
>NC_017186.1|WP_013223418.1|1622483_1623875_-|cyclic-nucleotide-binding-domain-containing-protein
MTVTEETTTSVQLSLSVRAARTLTTTTKTLPQMRGITTRWLLSQLPWVEVPAGSYRVNRRLTYTLGDGKLSFYNTGARVQVVPAELTELALLRDFGDETALRALAEAFEQREYEPGDTLFTTGTPLDTLFLLAHGKITRHTTGPYGDELHLGTATDGDHFGEELLGPHPGTWTFTARAATPVIALVLPAATYARLNGRSETLRTHVADALTRPRKPQNTKGEAAIDLAAGHDGEPLLPGTYVDYDPAPREYDLAVAQTVLRVHNRVSDLYNQPMNQLEQQLRLTVEALRERQEHELINNTDFGLLHNTDLKQRIPTRTGPPTPLDLDDLLCRRRKTRFFLAHPHAIAAFRRECTTRRIYPDTTILDGKRVTAWRGVPILPSDKIPITAAGTTTILAMRTGENDAGVIALRPKTLPDEYQPGLNVRNMNTNDHAITSYLISAYHSAAVLVPDALGALDDVQVGR
>NC_017186.1|WP_013223417.1|1621464_1622484_-|polyprenyl-synthetase-family-protein
MTTMNTRTAARPLADVLAWSKGLVDPALRTAAERLPETMRRIAAYHFGWQDADGRPAATDGGKALRPALVLLCAEAAGGEAADAVPAAVAVELVHNFSLLHDDVMDGDTTRRHRATAWTVFGTGPAVLAGDALLSLAFEVLAPSGAANAKVLSAATLALLEGQAADLDFEQRDDVTPGECIRMAEGKTAALLGAACTLGATSGPAGADRFGAFGRAVGLAFQHVDDLLGIWGDPAVTGKPVYSDLQNRKKSLPVVTALSSGTPAGADLATLYARREPLDETALARAASLVEAAGGRQWSQAQAEALLAKALRDLTAAAPPSRATAELTSLARLITTRTH
>NC_017186.1|WP_013223416.1|1620159_1621302_+|CapA-family-protein
MTKHRVAALAGVALLAAACSSPPQQAGPAPTPFPEASASSSSASAGAAPEGAFSVVATGDVLIHPALTEQAEADGGGKIDYRPLLAGIKPLISGADLGICHLETPLAPEGGPYSGYPSFSAPPEIADAIKDTGYDTCSTSSNHTIDQGADGVTRTLDKLDAAGVKHTGSARSAAEAAKPLILDVHGVKVAQVSYAFGFNGIKVPAGKPWLANQIDVDDVLAAARKAREAGAQVVIASLHWGVEYQHEPTAEQRSQAKKILASDDVDLIVGHHAHVVQPFEKIGGKWVAYGLGNSIARHSEPKGDTEEGTAARFRFVRDGDRWKVDKAEYIPTLIKLDAPIRLIDLSTSPPSPQVTKALQDTDKNILSLGADKAGLTRPGK
>NC_017186.1|WP_034284436.1|1635872_1636529_+|hypothetical-protein
MKRSKLRRIAGSGLVMAAVGALLAGGAAEATAAASGTVKTAGDPLNVRRAPTAGATAVKTVANGATVTIDCQVNGSSVTGTYGTGTLWDYVPALGGYISDTYVFTNSDTRVAPDCGVGSGSGQCADACAGEAQYRSSDSHFLVYDTNSDGYSAVVAYWLKGGAGPFYVWNSGGEGTKADKAVSVPHGSWVFYKVCVANYTTAKPDLKSCSDGITDFAA
>NC_017186.1|WP_013223428.1|1636560_1638132_+|alkaline-phosphatase-D-family-protein
MGQVNRRKVLLGGLAAVTATAASAALPSWANARTTVAAPAVHDPFQLGVASGDPLPDSVVLWTRLAPAPLSPDGFGGMPDATYAVDWEIANDAAFSSIVQSGSVSATRASAHSVHIEPTGLQPTREYFYRFRSSGYLSPVGRTRTAPAAGAAVNQLKYCFSSCQHWEEGYYHAYKGIVADDPDLVLFLGDYIYEKKSGRAAQERNPRSLAFTEDVTTLAQYRARHAQHKTDADLQAAHAIAPWIVVFDDHEVMNNWNGTTSPAPAARKAAGFQAFYENTPIRSTAKPDGASIQLYRQLMWGNLARFHMLDTRQYRSAQVADPAGDAGPACTDMRSTSRSILGATEEAWLLKQFESHPATWDFLGQQVFFATRDADGNKATCEGNDSWQGYEASRNRIQQGWVDRKVANPVVLTGDVHRHWAADLRLDYFDHSDPVIGSELVTTSVTSNSDTAAAPSAAWYANNPHVKYCKGERGYVRVTTTPSQMRADFVTTSDTSVYDPASVVIKNDASYVVQAGKPGLQKV
>NC_017186.1|WP_013223429.1|1638448_1639930_+|glycoside-hydrolase
MKKLLLITFAVAGLVVAGAGVSVAAPGGVYDVKDYGAKGNGSANDSAAIDKAITAANAAGGGTVRFTSGTYKSANTVHLKSNVTIQLDAGATITGSSADTYDKPESNQWDEYQDYGHSHFHNAMFYGDKLTNIGFTGAGTIDGGGNLITGNPKSGEADKILSLTRCDGLTLSGVKLRRGGHFAALINGCTNVVSDHLTIDTASDRDGWNIISTTNVTITNATIAANDDALVFKSDYALGAKLPNGNVTVNNAKLSAQCCNALMFGSETCGDFTGYQFSDITITSAHKSGIGIVSMDGAKISDVHYRNITMSGTYSPIMMKIGTRKRCGNNPGVGSISGITFDNVTGTHTGTNFSPTIWGADSGHRVSDVTFTGVKLSVPGGNGTMGTGVPSNTATDYNPKSIGTRPSYGWYLHYAAGIRFVNSSVEFAKDDGRPASIVNNSSDITFDHFTAEKGSKSPFDIGFQSVTGYCVKDSATTSGGTLRINTTSSTSTC
>NC_017186.1|WP_013223430.1|1640106_1641294_-|glycoside-hydrolase-family-88-protein
MSEHPLRPTRRAVLAGTLGALGALTAAGPLARAADRLPPIGGAAPPADWSRAVIDSTMKRYTPDKLGGWGYTLGLYLYGQYLFYKRTGEKKYLDYIIAWYDRFITDSGISNSFNNLDSMRSCQMLPLLYAETGRKKYKTAADQLRKRFPSYPRTSDGGMFHATSKVGQLWGDGVYMAQPFLALYGAAFGDGDYCFEESAKNIVVYFGHLREPAKNLLYHAYDEDGSESWASGTGHHSKYHWARAIGWFGMATIDILEVLPANHPRRAALIDVVNFLAAGYQRYQDASTGRWYQVVDRGGDSKNWLETSASSMYTFTMARGVQRGYLPASYQAVADRGYAGVLRKVSVGSDGLTNITDICEGTNVGDLSYYYGRARKTNDFHGLGAFLIMNEQYMH
>NC_017186.1|WP_013223431.1|1641646_1643419_+|alpha-L-fucosidase
MAAKFLRRALVACAATLAVSGLVAAPASADLQKPSQQWLRDSQAGLFLHWGMRTSPGYTSCSAWEKAITDGGWDPAYWVTEAEKLHASYLVLASFHSRLGYSRAWPSKIPGSCSTKRDFLGELVAAAKARGLKVILYMTNDAQWHDEGGHEWLDSAGYSKYKGKTVNLDSQDGFGQFSYDNFFEVMKNYPDLGGFWIDNDNAYWESHDLYQQIYQQRPDYLLSNNNEDTPIMDTISNEQKTGMTPSYDYPQATYTAMPRLTEACFKLPDTGSWWYGGSNSAVNKMLNIGRFITNSGSSIKSLMAETAMVNGKFPSNQEAFNNFAKTYLDAIWESLGGTEGAGYMYGGMQPGFWNDGAHGVITIKGGNQYVHVLTKPSTSTLKIRDNGYRVRRVTNLRTGAAISFSQGGGSLTLSGLSGWDSYDTVFKVETAGRTGTYDPATVTLKASASASGHGGQSASDGSYLTYFDNNKTLPVNLDYDLGAAKKVQYLGLNQREDSVSYARSDTEQSARIKAYKVFVSSDGKDWGSAVKSGTLPSHRGVQFVDLSAVTARYVRLQVTSTYAASSDSSRYKRLRIDETWVGSDYATAAG
>NC_017186.1|WP_013223432.1|1643459_1644689_-|hypothetical-protein
MNVTRERAAAVLAGNWLGASTVPSRALYPHQWSWDSAFIALGLRHLSPGRARRELRTLFTAQWADGRVPHIVFDPQTPPEAYFPGPSFWHAGRTSGLVQPPVHARAVLAVHRTEPDREFLAALYPKLVAWHDYLRTGRDAGGRGLVAIVHPWESGMDNSPAWDEPLTRVPPATGFVRRDLAHGDAGDRPSDDDYGRYVRLAAEYRDSGYRDFGRFAVEDPGFNALLADAELALAEIAEELDLPSAGHREAAARVQKAMQETLWDSAAGFFFARDVHTGSLVREYTCAGLLPLVLPDLAVAPALLATATGPRFRLGRVHGVPSYDLTAPGFDTGRYWRGPSWFNVGWLIRQGLLHHGEFALAERLGDDLVEIAARTDFAEYADPLTGAGHGTRTFSWTAALTVDLLSEGK
>NC_017186.1|WP_013223433.1|1644750_1645905_+|ROK-family-protein
MTTPTSAGELLQLVRTGQASTRKALLERSGLSRSTLTARLEQLQTAGLLAEGGQEDSTGGRPARQLCFDDRHAVVLAASIDTTHAEAAVTDLAGRVLARRAGAVRVADGPEPVLDRIAEWFEALRAEAARPVCGVGVSVPGPVEPGRARVTQPPIMPGWDGYPIDAHLGARFGAPVLVDNDANLMALGEHRARHPESAALVVVKVSTGIGAGLVLGGEVYRGIDGGAGDIGHIRLPDHPEARCPCGSLGCLAAVAGGGALAAKLTALGLPTESGSGVRDRITAGDPAAVRLAEVAGRQVGAVLATLVCVVNPGVVVIAGDLAEPHFVAGVREVLYRRALPRATQNLRVEIGGRGEGMAVAGAVAMVVDAVFAPAEVDRRLAARV
>NC_017186.1|WP_013223434.1|1646208_1648140_+|S8/S53-family-peptidase
MRRSSTLLLSLAVVGGLTGTLPATASAQGRQDIPQSHPLWANAQAKVADTAPAAKLSFRVYLNQRDNAGAEALAQAVSDPDSKTYRQYLSPDQVRDRFAASDATVGAVKAWLTGNGFSIGEIPSNRAYVEATGTADQTEKAFAVDLGKYRVKGQTLRAADKNLSVPANLAGDVLGVVGVDQATNLFKPDHATGSGTPSDVAPGPGFRNAPPCSAYYGEKIDTTDPAYNGKQLPYAPCGYTPSQLRSAYGIDKLGADGKGTTIAIVDAFASPTIYSDASTYAKKNDPQHPLKQSQFSQHVFPVNPVLEPADQCDAAGWYGEETLDVEAAHGLAPGADILYVGGSDCQDNSLDEALNYVVAGHKADIVSNSYGDTGEDIPADEVKVFNQISLQAVLEGIGVYFSSGDNGDEVARLGTPSPDFSASAPWITAVGGTSIAIGKDGKKIFESGWETSKSVLTNGVYGPANYTSGSGGGTSRLFEQPFYQKGVVPDALAKKNQTGNKKGRVVPDISAVGDPNTGFLVGQTQTFPEGAHYDQYRIGGTSLASPVFAGIMAVADSFDHFHHGFINPVIYKLTSRTPAISDVKHVDAAVARVDYANSVDASAGLLHSVRTLDYQGLTIHTTPGYDDVTGLGVPNGLLFLLLV
>NC_017186.1|WP_013223435.1|1648230_1649766_-|sensor-histidine-kinase
MQHPRTSAMTGLLAAGCALGVVALTLKAGEGSHSARDTALSTTTGFLFLLAGAVAHVRRPANPIGVLIALVGVALFLEDLQFAQNPVLYTIAVPLRAASSPVIAHLVLAFPHGRLRSRWERLLVAAAYLVVLGSGVVGLLVDDDPRDLLALWPGSGALADRALEPAATAVSAGVVVVLLYRWLTGRLPQRRLLSPVVVIALAGALTSGAGTALGDAHPLSGPLLQAYRILFCLWPLAFLAGVMRARVGNAEMVRLLLERDGTGLAALVQDDEVWKDSRSIDALNAAAGLVLDNQRLTAELEQRLAEVRASRARLVAAGDEERRRLERDLHDGAQQRLVSVVLLLRMAGRRSGAELPPEIRALLTGAVDELQTAITELRELARGIRPAILTEAGVVAAVRSLADRIPMEVALTVGTVPRLDAAVEATAYFVTSEALTNALKHARTDRADVRIEVAGAELRVEVTDAGVGGADPEGGSGLAGLRDRVQALGGELDVASGPGGTAVTAVIPLAG
>NC_017186.1|WP_013223436.1|1649900_1651274_+|cytosine-permease
MSGHGLDADVFGGRMPAGGRDLAIETHGIAPVPEDNRFGRPWRLFSVWFAPNLTMTAVFTGTLAASLGLGFWTGLAAMLAGTVLGSLPVAYLSTWGPRTGTGQLPLARLPFGGGVVLPGLVQWLGSIAWDALVGLFGGEALAELTGLPFWAAVLIVLVLQCALGVFGYALIHRVQAVMSVLLLLAFAALAVKVLSGHPIAGAGTASGAGLAGGVVLFTTITLSLAISWAPYASDFSRYLPVSASSRAVFWATLLGLVVSYAIGEGLGLALGSSLGDQTAAGVAQLLGGGFLGALALAVIALAAVSSNAMNDYSGSLALQTVGVRLRRPVSAVVVTVLAFALILWMHSGDLSAKFQNVLLFVSYWIPPFLGVVVPDWLARTRGGRRVDVLASVSVRPWAAVVAFLVGFGAAVPFMNTTLYTGPVAAALHGADLAYYVGLVVSLAAYFLLRGRSSVDLK

Crispr_ID: NC_017186_7

• CRISPR_ID: NC_017186_7
• CRISPR_location: 1931492-1931584
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_7

Consensus_repeat	Method
GCGGGCGTGCTCGGGTGGCATCGC	CRISPRCasFinder

spacers of NC_017186_7

>7.1|1931516|45|NC_017186|CRISPRCasFinder
GTCCGACTGCCGCGAGGGGAGTGTTGCCGTGTGTTGCTGGTGCGG

CRISPR arrays and Neighbor proteins around NC_017186_7

CRISPR arrays

The CRISPR arrays of NC_017186_7

>merge|NC_017186|7|1931492-1931584|CRISPRCasFinder
GCGGGCGTGCTCGGGTGGCATCGCGTCCGACTGCCGCGAGGGGAGTGTTGCCGTGTGTTGCTGGTGCGGGCGGGCGTGCTCGCGTGGCATCGC

>NC_017186|7|6|1931492-1931584|CRISPRCasFinder
GCGGGCGTGCTCGGGTGGCATCGC	GTCCGACTGCCGCGAGGGGAGTGTTGCCGTGTGTTGCTGGTGCGG
GCGGGCGTGCTCGCGTGGCATCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013223698.1|1935109_1936336_+|hypothetical-protein	unknown	unknown	gnl|CDD|285278
NC_017186.1|WP_013223701.1|1938345_1939692_+|glutamine-synthetase	unknown	unknown	gnl|CDD|223252
NC_017186.1|WP_013223685.1|1924741_1925242_+|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NC_017186.1|WP_013223692.1|1930056_1930926_+|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	unknown	unknown	gnl|CDD|234899
NC_017186.1|WP_013223693.1|1930984_1931419_+|helix-turn-helix-domain-containing-protein	unknown	unknown	unknown
NC_017186.1|WP_013223697.1|1934789_1935113_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NC_017186.1|WP_013223703.1|1940394_1941762_+|aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|365919
NC_017186.1|WP_013223686.1|1925241_1925913_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_034284376.1|1926934_1927522_+|DUF177-domain-containing-protein	unknown	unknown	gnl|CDD|224317
NC_017186.1|WP_013223699.1|1936419_1937382_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|184875
NC_017186.1|WP_013223691.1|1928642_1929998_+|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl|CDD|271210
NC_017186.1|WP_013223689.1|1927609_1927792_+|50S-ribosomal-protein-L32	unknown	unknown	gnl|CDD|237038
NC_017186.1|WP_176742189.1|1927805_1928555_+|ribonuclease-III	unknown	unknown	gnl|CDD|234633
NC_017186.1|WP_013223687.1|1926025_1926754_+|DivIVA-domain-containing-protein	unknown	unknown	gnl|CDD|226127
NC_017186.1|WP_013223696.1|1933789_1934692_-|SMP-30/gluconolactonase/LRE-family-protein	unknown	unknown	gnl|CDD|225921
NC_017186.1|WP_013223702.1|1939693_1940398_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl|CDD|224982
NC_017186.1|WP_013223700.1|1937591_1938116_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223695.1|1932394_1933573_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223684.1|1923985_1924678_+|ribonuclease	unknown	unknown	gnl|CDD|238340
NC_017186.1|WP_013223694.1|1931912_1932398_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013223698.1|1935109_1936336_+|hypothetical-protein	gnl|CDD|285278	pfam08006, DUF1700, Protein of unknown function (DUF1700). This family contains many hypothetical bacterial proteins and putative membrane proteins.	2.23876e-09
NC_017186.1|WP_013223701.1|1938345_1939692_+|glutamine-synthetase	gnl|CDD|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	2.51263e-136
NC_017186.1|WP_013223685.1|1924741_1925242_+|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.35512e-32
NC_017186.1|WP_013223692.1|1930056_1930926_+|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase	gnl|CDD|234899	PRK01103, PRK01103, bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase.	2.02136e-145
NC_017186.1|WP_034284376.1|1926934_1927522_+|DUF177-domain-containing-protein	gnl|CDD|224317	COG1399, COG1399, Predicted metal-binding, possibly nucleic acid-binding protein [General function prediction only].	7.29897e-27
NC_017186.1|WP_013223699.1|1936419_1937382_+|alpha/beta-fold-hydrolase	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	6.35086e-37
NC_017186.1|WP_013223691.1|1928642_1929998_+|right-handed-parallel-beta-helix-repeat-containing-protein	gnl|CDD|271210	cd14251, PL-6, Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.	1.02583e-120
NC_017186.1|WP_013223689.1|1927609_1927792_+|50S-ribosomal-protein-L32	gnl|CDD|237038	PRK12286, rpmF, 50S ribosomal protein L32; Reviewed.	1.41297e-23
NC_017186.1|WP_176742189.1|1927805_1928555_+|ribonuclease-III	gnl|CDD|234633	PRK00102, rnc, ribonuclease III; Reviewed.	7.34871e-113
NC_017186.1|WP_013223687.1|1926025_1926754_+|DivIVA-domain-containing-protein	gnl|CDD|226127	COG3599, DivIVA, Cell division initiation protein [Cell division and chromosome partitioning].	4.42596e-24
NC_017186.1|WP_013223696.1|1933789_1934692_-|SMP-30/gluconolactonase/LRE-family-protein	gnl|CDD|225921	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism].	1.74688e-73
NC_017186.1|WP_013223702.1|1939693_1940398_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl|CDD|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	8.19334e-77
NC_017186.1|WP_013223703.1|1940394_1941762_+|aldehyde-dehydrogenase	gnl|CDD|365919	pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. The family includes the following members: The prototypical members are the aldehyde dehydrogenases EC:1.2.1.3. Succinate-semialdehyde dehydrogenase EC:1.2.1.16. Lactaldehyde dehydrogenase EC:1.2.1.22. Benzaldehyde dehydrogenase EC:1.2.1.28. Methylmalonate-semialdehyde dehydrogenase EC:1.2.1.27. Glyceraldehyde-3-phosphate dehydrogenase EC:1.2.1.9. Delta-1-pyrroline-5-carboxylate dehydrogenase EC: 1.5.1.12. Acetaldehyde dehydrogenase EC:1.2.1.10. Glutamate-5-semialdehyde dehydrogenase EC:1.2.1.41. This family also includes omega crystallin, an eye lens protein from squid and octopus that has little aldehyde dehydrogenase activity.	0
NC_017186.1|WP_013223697.1|1934789_1935113_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	6.9395e-18
NC_017186.1|WP_013223684.1|1923985_1924678_+|ribonuclease	gnl|CDD|238340	cd00607, RNase_Sa, RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate specific endoribonuclease which belongs to the superfamily of microbial ribonucleases. Typical of this sub-family, the enzyme hydrolyses the phosphodiester bonds of RNA at the 3' oxygen end of guanosine residues to yield oligonucleotides with the guanosine-2',3'-cyclophosphate at the 3' end and the hydroxyl group at the 5' end. The terminal guanosine-2,3'-cyclophosphate is hydrolysed by guanyl RNAses to give guanosine-3'-phosphate.	8.07832e-42

Protein sequences

>NC_017186.1|WP_013223693.1|1930984_1931419_+|helix-turn-helix-domain-containing-protein
MVKEPGKSTLADKIDRLFHVVRRPDREPYSNEEVAKACREATGESFSTTYLWQLRTGRRDNPTKRHLEALAQFFGVPPAYFFDDEQSRKIAEELALLGALRDAGVRDLALRAVTLSSDGLDTISDMIDAIARREAGRGGPKKES
>NC_017186.1|WP_013223692.1|1930056_1930926_+|bifunctional-DNA-formamidopyrimidine-glycosylase/DNA-(apurinic-or-apyrimidinic-site)-lyase
MPELPEVEVVRLGLQVHVAGRTIREAEVLHPRAIRRHALGAEDFTQRLAGTRVEAARRRGKYLWLELSDKEALLAHLGMSGQMLVQPEGAPDEKHLRVRLRFEDDGPELRFVDQRTFGGLALDDLSDIGSEVLLPDTIAHIARDPMDPEFDLDAAVRALRSRRTEVKRALLDQTLVSGIGNIYADEALWRARLHWARPTEKLTMAKGRELLSAASDVMNAALGAGGTSFDALYVNVNGQSGYFDRSLDAYGQEGMPCHRCGTAIRREPFMNRSSFSCPRCQPRPRANSG
>NC_017186.1|WP_013223691.1|1928642_1929998_+|right-handed-parallel-beta-helix-repeat-containing-protein
MRLFFVPLIAAALVVVPGPAASAAQVRVTSLAALQSAMDKANPGDTIVLADGSYSAGSTLSIKRSGTSTAPVTVAAEHTGQATITGSKTFAFASGVSNVVLRGFKFRGSAKLSVPAGASNNRLTRNDFQLTADGNWVTVSGDDTVVDRNVFQNRTSQGVFLQILGPSGAMAKRVHVHHNYFYNHQFSGSNGGESIRLGLSDHQSYTANALIENNLFEKADGDSEAISVKSSDNVVRYNTIRDSRGYIVLRHGNRSTVEGNVLFGSGIRFHGNDHKIVNNYVANSGGRAIVFGSGDEADSGPTSKLHDRPDRDTVAYNTVIGSSSVIDGDGGNFKPKDCVVADNIVEGTSGTLVTLPSGSTVKYEGNITSGGTAGIPSRSVDPKLVKDAAGLYRLASGSPAIDAGVGSYPFAAKDFDLQARGGAYDVGADEYFATGATRVPLTKADVGPSAP
>NC_017186.1|WP_176742189.1|1927805_1928555_+|ribonuclease-III
MGGKTPGGPPADPAPLLEALGVILDPELLRLSLTHRSYAYENGGLPPNERLEFLGDAVLGLVVTDHLYNTHPDLPEGQLAKLRASVVNMHALARVARGLGEGGLGAHLLLGKGEELTGGRDKASILADGLEAVIGAVYLEHGIEIARKLVHHLFDGLLAEAPLRGAGLDWKTSLQELTASAGLGVPEYKVEDTGPDHRKEFTATVLVAGRPLGHGAGSTKKEAEQKAAETAWRSLSAEVEAQKKAEPES
>NC_017186.1|WP_013223689.1|1927609_1927792_+|50S-ribosomal-protein-L32
MAVPKRKMSRSNTRSRRSQWKAAPVQLVPCSNRACKQPKLQHIACPSCGQHNGRQVVEPA
>NC_017186.1|WP_034284376.1|1926934_1927522_+|DUF177-domain-containing-protein
MSENKTPQLDDRSPWVIDTRELGRHAGLSRALQRSVPVETPLGVPDVITIEAGSELELDLLLESVVEGVLVSGTAKALAKGTCARCLDPLTEEVEVEVQELFAYPGSATEETTDEDEIPRLIDDRIDLEPIVRDAVVLALPLAPLCTEDCAGLCIECGVKWADLEPGHGHEKIDPRWAALVERFDENAGEKPGPS
>NC_017186.1|WP_013223687.1|1926025_1926754_+|DivIVA-domain-containing-protein
MYRVFEALDELVTIVEEARGVPMTASCVVPRGDVLELLDDVRDALPAEIDDAQDVLDKRDDLIHAARKEAGETVAGANAEAERAIADATDEAERILADARARAEQMLADAHDQADRTVAAGQAEYQNLTDRSRAESERMIQAGRDAYDRAIEDGRAEQARLVAQTEVVQAAHAESARIVDEAHAEADRQRADCDAYVDGKLAEFSELLATTLRTVDSGRNHLRSPANLPSSGGRPTLYDYQV
>NC_017186.1|WP_013223686.1|1925241_1925913_+|hypothetical-protein
MPELETRLREVDVPEPPLGFDPDEVADRAARHARRRSATVLLTAVAALAALFPTTVREPVVPAAAPVPSLAEQSRIRLALAEAVTRALPGVHDLILGRSSADSTGPARMSVTAEFVDAGGRPSTFQLTVRGARAAREVVPIDGLCTWPDQTPHCVRLPLPGGGVLVLSELGYKDGNGTFVRVGINGFLYRPDGSTVILTGGLRYPLSEEQVTKVITDPAFVLR
>NC_017186.1|WP_013223685.1|1924741_1925242_+|SigE-family-RNA-polymerase-sigma-factor
MRAADDADFREFARARALTLRRTAYLLCGDWHLAEDLVQNALLKLYRVWPKITRRGPVDNYARQVLLRCWLDESRRPWRRRERRDGVVPDQPTSSPEAGISDPLLRALAEVPPKQRAAVVLRYCAGLPAAEVAEVLRCSEGTVRSQAARGLETLRGVLEHSAERSA
>NC_017186.1|WP_013223684.1|1923985_1924678_+|ribonuclease
MANYRSRLVAVLFALLATLFAGVTAASAASPAVVAQNACGNLSGYSHTTLSALPPEATTTYHLIQTDGPFPYPKNDGVVFDNREGVLPACASGYYHEYTVPTPGSSTRGTRRIVTGSAGEYFYTGDHYATFKVIDIGGGTTHACGDLSGLAKIGYSQLSSAARTVVDDVRNGTSAGTTYENREGVLPACASGYYKLFAVGTNDRVISGKAGELAYTPDHYATFKRIDLNS
>NC_017186.1|WP_013223694.1|1931912_1932398_+|hypothetical-protein
MSLPEPFDAEDFVAGLAAERGRPIELMPVSAPQGAPCGLLMSTERADYILYPTDTTALHRRHILLHEVGHLLCGHVGADAGADGVAIDAAAGRQLMPNLSPELVRRVLGRTTYSEVEEREAELVASLLAQRVVRPAEPRDPAPGVPEGVRRFDSLFGRRAP
>NC_017186.1|WP_013223695.1|1932394_1933573_+|hypothetical-protein
MIETLAYYLCTAGFAGFGYKLIEARRSQPVRTMWFLAGFGTCIAAGILVLTPAMSALAGPGPVAEWVLNLAGDELKLGAIGFAVAFTQSVWRGDGARLAPHALFTAATMVLLAACFALSEPRRVGDDTIFSDAALPFAVGDKVLFLVYSLISLGLLLAVFVRSAWHAEPGPLRAGLWLLVVGVGAAAAWTFWDVDDVVQLARTGRIGAREDLPSSVLAAVTIVFVAAGATLSAWSPAVSSVVGRVRAYRAYRRIEPLWTALRTAVPGIALDPGRKLAGGAEFALYRRVIEIRDGHLALRAHFDPDLPARAEAAARRAGVREAEVAATVEAVTLAAAIEAGRAGRRFAREPDHPAEPDTAADVATEAAWLVQVSRAWRRRDAVVERVEAATPG
>NC_017186.1|WP_013223696.1|1933789_1934692_-|SMP-30/gluconolactonase/LRE-family-protein
MDVVKTDFQLLDERFARVNGDEWTQRLHTGCRWTEGPAYFPAGRYLVFSDIPNDRTLRWDETTGRVGVFRQPSRYANGHTVDRQGRLISCEQGPRRVTRTEHDGSITVLASEYRGKRLNSPNDVVEHSDGSIWFTDPSYGIDSDYEGYRAESEIGACHVYRAAPDGSVTIVADDFSRPNGLAFSADESRLYIADTRQDPSHIRVFSVAGNGKLTGGEIFATSDSGGFDGVRVDSEGQVWAAAHDGLHCFASDGTRIGKLRIPEVCSNFTFGGARGNELFITASSSLYTLRVTVNGARYPR
>NC_017186.1|WP_013223697.1|1934789_1935113_+|PadR-family-transcriptional-regulator
MEISQLLKGVLDLAVLAVLRDEDGYGYDVLRRLRAAGLDEVGDASVYGTLRRLYKAGLLTSYVVPSEEGPHRKYYSLNEPGRVRLAESGKTWQSFASTMNALLGEAA
>NC_017186.1|WP_013223698.1|1935109_1936336_+|hypothetical-protein
MSDKPTAVRVYLARVRTALADLPASEIEEILEDVRPHLAELEAELGEGARVEALIERLGSPESYAAELRASGGYPAPGEGGTQVLATAGTGLVKPRIALWGLVFCSLGLALLAFSATVSRSLDAFGGLLLFAPVFFVSLTLLLRGGVEPVLALPEVGWLRATMAKGREQQDTGKFLRYAGSLKPAWWVVCAVVLVSFGLLLMLRHRSAVLLLPLLVLGAVGALWAGPRVRTDRRLLWMAVPISAFVIGGALGGFSVAIDLVSRGTAYSGPTSYSPSSVDHYGNDQLTYGGREVENVYAFDAEGKPLTEVYLYDEEGRPLTLTRYACEPATGGTRKLGEDNRFPRPKIEQGVTDDRGNYNGYNGYRGACRELAGVPFSAAIPKVTVPAATTTPSTSPTPTPTPTPTPTR
>NC_017186.1|WP_013223699.1|1936419_1937382_+|alpha/beta-fold-hydrolase
MTPRTDSLAPHTRVVHGYERAYRMAGSGPALLFLHGIGDDSSTWLDLLASLSADFTVIAPDLLGHGSSAKPRADYSVAAYACGMRDLLTTLDVDRVTVVGHSLGGGVAMQFAYQFPERCERLVLVGSGGVGAGVHPLLRLAAAPGAGLVLPLLGTPPAVAALRGFAGLLRLFDDADLDYVLTRYARLVEPGTRSAFLRTLRSVVDWRGQVVNMLDRCYLTEGIPTLLIWGTEDRVVPSGHALRAHRAMPGSRLVLFEGAGHFPHRADPERFLEILREFLATTPPARYDRARWGKLLRAGRPAEAPETAGVPDVPTVSSGT
>NC_017186.1|WP_013223700.1|1937591_1938116_-|hypothetical-protein
MTTAFTQQTTIGQQQARPQLPTLPTGWPIGSYESYEQAQRAVDHLAGTDFPVTDVTIVGVEPMLVERVAGKMTWGKVLGSAATSGALFGLFLGLMLSLLNPGAGLVPIVIGLVAGLGFNLLFGALGYAANRNKRGFVSQSQLVARRYDVLSQPRNAEKGRALLADLAARSAFGH
>NC_017186.1|WP_013223701.1|1938345_1939692_+|glutamine-synthetase
MLTLDELRARVDAGTVDTVLVALTDMQGRLQGKRCSAEYFLDEVVGHATEACNYLLAVDVDMNTVGGYALSSWDSGYGDFVLRPDLETLREIPWQEGTALVLADVERVQGGPVSVSPRQILRRQLDRLAERGLAAFVGTELEFIVFDDTYEAAWDKRYHGLKPANQYNVDYSMLGTARLEPLLRRIRNDMAGAGLYPESAKGECNPGQQEIAFRYTDALSTCDNHSVYKNGAKEIAAQEGKSLTFMAKYNEREGNSCHIHISLRSTEGRAVLAGDGEHGFSKLMEHFLAGQLAALHELTYFLAPNVNSYKRFVPGSFAPTAIAWGTDNRTCALRVVGHGESLRVENRVPGGDVNPYLAVAALVAAGLHGIENELELEEPFTGNAYNSDRDTVPATLPEAAAALAGSGLARAAFGDDVVDHYLNAAKVEIDAYNAAVTDWELVRGFERL
>NC_017186.1|WP_013223702.1|1939693_1940398_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MNRGKPVIGLTGYLEPAKFGVWETEAVLLHRVYVDCVVAAGGLPVLLPPVSDGYERLVSTVDGLVLTGGADVEPARYGQEPHPATYVRPERDVFEFGLFAAARKAGKPVLGVCRGLQVMSVALGGTLVQHLPESARTTEHQPAPATFGRGTVTLAEGSRAAAILGPETKTLCYHHQAIDRLGTGMQAVGWSADGTIEAAEVPGEFTMGVQWHPEQDSDDIRLFQALVEASKERE
>NC_017186.1|WP_013223703.1|1940394_1941762_+|aldehyde-dehydrogenase
MTSSFDVLNPATEEVVRTVPLTSAEETDAAIARAHAAFPAWRDVAPGDRARLLRRFADAVEADIEHLARLEVENSGHTIGNARWEAGNVRDVLNYYSAAPERLIGKQIPVPGGINVTFQEPLGVVGVIVPWNFPMPIAGWGFAPALAAGNTVVLKPAELTPLTAIRLAELAREAGIPEDVFQVLPGKGSVVGQRFVEHPAVRKVVFTGSTEVGKQIMAGCAAQVKRVTLELGGKNANIVFADSDLEKAAATAPYGVFDNAGQDCCARSLILVQASAYDRFMELLEPAVHGVVVGDPGDEKTEMGPLISAAHREKVASYVPDDAPVAFRGTAPAGRGFWFPPTVLTPPDLRHPVAAEEVFGPVVAVVPFAEEADAIRMANATEYGLSGSIWTRDAGRAFRVARGVEAGSLSVNSHSSVRYWTPFGGFKQSGLGRELGPDAAAAFTETKNVFLSTEE

Crispr_ID: NC_017186_8

• CRISPR_ID: NC_017186_8
• CRISPR_location: 2088131-2088553
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NC_017186_8

Consensus_repeat	Method
GNCGTGCGCAACCGCGAGTCCTGA	CRT
TGCGCAACCGCGAGTCCTGAGCC	CRISPRCasFinder
CCGGAAGGAGAGCTGCCGTGCGCAACCGCGAGTCCTGAG	PILER-CR

spacers of NC_017186_8

>8.1|2088155|43|NC_017186|CRT
GCCTCCCCGTCCCGAAGTCCGCGCGTACCGCCGGAGGGAGGCT
>8.2|2088222|39|NC_017186|CRT
GCCGCTGTGACCTCTGTTTGTCGTGTCGAGAGGAGGGCT
>8.3|2088285|41|NC_017186|CRT
GCTGTCGTGTCCCTTGTTCGCCTGTGTCCGGAAGGAGGGCT
>8.4|2088350|42|NC_017186|CRT
GTGGCCGTGTCCCGATGTTCGCCCGCGCCCGGAGGGAGAGCT
>8.5|2088416|41|NC_017186|CRT
ACCGATGCCCACCCAGCCGACCGCGTGCCGGAAGGAGAAGT
>8.6|2088481|46|NC_017186|CRT
GCCCAGCCGTGTACCCAGTCCGTTCCCGCCCGAGAGAGGAATCGTC
>8.7|2088158|44|NC_017186|CRISPRCasFinder
TCCCCGTCCCGAAGTCCGCGCGTACCGCCGGAGGGAGGCTGTCG
>8.8|2088225|40|NC_017186|CRISPRCasFinder
GCTGTGACCTCTGTTTGTCGTGTCGAGAGGAGGGCTGTCG
>8.9|2088288|42|NC_017186|CRISPRCasFinder
GTCGTGTCCCTTGTTCGCCTGTGTCCGGAAGGAGGGCTGTCG
>8.10|2088353|43|NC_017186|CRISPRCasFinder
GCCGTGTCCCGATGTTCGCCCGCGCCCGGAGGGAGAGCTGCTG
>8.11|2088419|42|NC_017186|CRISPRCasFinder
GATGCCCACCCAGCCGACCGCGTGCCGGAAGGAGAAGTGCCG
>8.12|2088484|47|NC_017186|CRISPRCasFinder
CAGCCGTGTACCCAGTCCGTTCCCGCCCGAGAGAGGAATCGTCACCA
>8.13|2088351|27|NC_017186|PILER-CR
TGGCCGTGTCCCGATGTTCGCCCGCGC
>8.14|2088417|26|NC_017186|PILER-CR
CCGATGCCCACCCAGCCGACCGCGTG

CRISPR arrays and Neighbor proteins around NC_017186_8

CRISPR arrays

The CRISPR arrays of NC_017186_8

>merge|NC_017186|8|2088131-2088553|CRT,CRISPRCasFinder,PILER-CR
GTCATGCGCAACCGCGAGTCCTGAGCCTCCCCGTCCCGAAGTCCGCGCGTACCGCCGGAGGGAGGCTGTCGTGCGCAATCGCGAGTCCTGAGCCGCTGTGACCTCTGTTTGTCGTGTCGAGAGGAGGGCTGTCGTGCGTAATCGCGAGTCGTGAGCTGTCGTGTCCCTTGTTCGCCTGTGTCCGGAAGGAGGGCTGTCGTGCGCAACCGCGAGTCCTGAGTGGCCGTGTCCCGATGTTCGCCCGCGCCCGGAGGGAGAGCTGCTGTGCGCAACCGCGAGTCCTGAACCGATGCCCACCCAGCCGACCGCGTGCCGGAAGGAGAAGTGCCGTGCGCAACCGCGAGTCCTGAGCCCAGCCGTGTACCCAGTCCGTTCCCGCCCGAGAGAGGAATCGTCACCATGCGCAACCGTGAGTCGTGAATT

>NC_017186|8|2|2088131-2088550|CRT
GTCATGCGCAACCGCGAGTCCTGA	GCCTCCCCGTCCCGAAGTCCGCGCGTACCGCCGGAGGGAGGCT
GTCGTGCGCAATCGCGAGTCCTGA	GCCGCTGTGACCTCTGTTTGTCGTGTCGAGAGGAGGGCT
GTCGTGCGTAATCGCGAGTCGTGA	GCTGTCGTGTCCCTTGTTCGCCTGTGTCCGGAAGGAGGGCT
GTCGTGCGCAACCGCGAGTCCTGA	GTGGCCGTGTCCCGATGTTCGCCCGCGCCCGGAGGGAGAGCT
GCTGTGCGCAACCGCGAGTCCTGA	ACCGATGCCCACCCAGCCGACCGCGTGCCGGAAGGAGAAGT
GCCGTGCGCAACCGCGAGTCCTGA	GCCCAGCCGTGTACCCAGTCCGTTCCCGCCCGAGAGAGGAATCGTC
ACCATGCGCAACCGTGAGTCGTGA

>NC_017186|8|7|2088135-2088553|CRISPRCasFinder
TGCGCAACCGCGAGTCCTGAGCC	TCCCCGTCCCGAAGTCCGCGCGTACCGCCGGAGGGAGGCTGTCG
TGCGCAATCGCGAGTCCTGAGCC	GCTGTGACCTCTGTTTGTCGTGTCGAGAGGAGGGCTGTCG
TGCGTAATCGCGAGTCGTGAGCT	GTCGTGTCCCTTGTTCGCCTGTGTCCGGAAGGAGGGCTGTCG
TGCGCAACCGCGAGTCCTGAGTG	GCCGTGTCCCGATGTTCGCCCGCGCCCGGAGGGAGAGCTGCTG
TGCGCAACCGCGAGTCCTGAACC	GATGCCCACCCAGCCGACCGCGTGCCGGAAGGAGAAGTGCCG
TGCGCAACCGCGAGTCCTGAGCC	CAGCCGTGTACCCAGTCCGTTCCCGCCCGAGAGAGGAATCGTCACCA
TGCGCAACCGTGAGTCGTGAATT

>NC_017186|8|1|2088312-2088481|PILER-CR
CCGGAAGGAGGGCTGTCGTGCGCAACCGCGAGTCCTGAG	TGGCCGTGTCCCGATGTTCGCCCGCGC
CCGGAGGGAGAGCTGCTGTGCGCAACCGCGAGTCCTGAA	CCGATGCCCACCCAGCCGACCGCGTG
CCGGAAGGAGAAGTGCCGTGCGCAACCGCGAGTCCTGAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013223834.1|2081669_2083979_+|[protein-PII]-uridylyltransferase	unknown	unknown	gnl|CDD|235123
NC_017186.1|WP_013223845.1|2094129_2095668_+|signal-recognition-particle-protein	unknown	unknown	gnl|CDD|236780
NC_017186.1|WP_013223841.1|2090091_2090454_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223836.1|2085382_2086045_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013223840.1|2089383_2089971_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_017186.1|WP_013223833.1|2081320_2081659_+|P-II-family-nitrogen-regulator	unknown	unknown	gnl|CDD|223424
NC_017186.1|WP_013223831.1|2078913_2079612_-|rRNA-(guanine-N1)-methyltransferase	unknown	unknown	gnl|CDD|236841
NC_017186.1|WP_071831524.1|2079935_2081324_+|ammonium-transporter	unknown	unknown	gnl|CDD|223083
NC_017186.1|WP_014466736.1|2088607_2089360_-|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|180440
NC_017186.1|WP_013223835.1|2084058_2085390_-|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|235870
NC_017186.1|WP_013223844.1|2092155_2093934_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_017186.1|WP_034286213.1|2090506_2091388_+|Ku-protein	unknown	unknown	gnl|CDD|238408
NC_017186.1|WP_013223846.1|2095676_2096753_+|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|238624
NC_017186.1|WP_013223848.1|2097626_2098430_+|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NC_017186.1|WP_013223830.1|2078268_2078895_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|378676
NC_017186.1|WP_013223838.1|2086712_2088017_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_017186.1|WP_013223843.1|2091666_2092146_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_017186.1|WP_013223829.1|2077417_2078272_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|236600
NC_017186.1|WP_176742119.1|2086041_2086644_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|132427
NC_017186.1|WP_013223847.1|2096799_2097525_+|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013223834.1|2081669_2083979_+|[protein-PII]-uridylyltransferase	gnl|CDD|235123	PRK03381, PRK03381, PII uridylyl-transferase; Provisional.	0
NC_017186.1|WP_013223845.1|2094129_2095668_+|signal-recognition-particle-protein	gnl|CDD|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NC_017186.1|WP_013223840.1|2089383_2089971_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.94575e-10
NC_017186.1|WP_013223833.1|2081320_2081659_+|P-II-family-nitrogen-regulator	gnl|CDD|223424	COG0347, GlnK, Nitrogen regulatory protein PII [Amino acid transport and metabolism].	1.57751e-53
NC_017186.1|WP_013223831.1|2078913_2079612_-|rRNA-(guanine-N1)-methyltransferase	gnl|CDD|236841	PRK11088, rrmA, 23S rRNA methyltransferase A; Provisional.	1.43816e-20
NC_017186.1|WP_071831524.1|2079935_2081324_+|ammonium-transporter	gnl|CDD|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	6.58223e-158
NC_017186.1|WP_014466736.1|2088607_2089360_-|glucose-1-dehydrogenase	gnl|CDD|180440	PRK06172, PRK06172, SDR family oxidoreductase.	6.18095e-82
NC_017186.1|WP_013223835.1|2084058_2085390_-|FAD-dependent-monooxygenase	gnl|CDD|235870	PRK06834, PRK06834, hypothetical protein; Provisional.	3.59423e-110
NC_017186.1|WP_013223844.1|2092155_2093934_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.60307e-163
NC_017186.1|WP_034286213.1|2090506_2091388_+|Ku-protein	gnl|CDD|238408	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku homologs are predicted to form homodimers. It is proposed that the Ku homologs are functionally associated with ATP-dependent DNA ligase and the eukaryotic-type primase, probably as components of a double-strand break repair system.	2.51351e-95
NC_017186.1|WP_013223846.1|2095676_2096753_+|amidohydrolase-family-protein	gnl|CDD|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	1.77369e-62
NC_017186.1|WP_013223848.1|2097626_2098430_+|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.01052e-09
NC_017186.1|WP_013223830.1|2078268_2078895_-|(2Fe-2S)-binding-protein	gnl|CDD|378676	pfam11575, FhuF_C, FhuF 2Fe-2S C-terminal domain. This family consists of several bacterial ferric iron reductase protein (FhuF) sequences. FhuF is involved in the reduction of ferric iron in cytoplasmic ferrioxamine B. This domain is the C-terminal domain that contains 4 conserved cysteine residues that are found to be part of a 2Fe-2S cluster.	0.0021228
NC_017186.1|WP_013223838.1|2086712_2088017_-|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	3.09927e-61
NC_017186.1|WP_013223843.1|2091666_2092146_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.02881e-14
NC_017186.1|WP_013223829.1|2077417_2078272_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	3.64095e-73
NC_017186.1|WP_176742119.1|2086041_2086644_-|TetR-family-transcriptional-regulator	gnl|CDD|132427	TIGR03384, betaine_BetI, transcriptional repressor BetI. BetI is a DNA-binding transcriptional repressor of the bet (betaine) regulon. In sequence, it is related to TetR (pfam00440). Choline, through BetI, induces the expression of the betaine biosynthesis genes betA and betB by derepression. The choline porter gene betT is also part of this regulon in Escherichia coli. Note that a different transcriptional regulator, ArcA, controls the expression of bet regulon genes in response to oxygen, as BetA is an oxygen-dependent enzyme. [Regulatory functions, DNA interactions].	1.6171e-14
NC_017186.1|WP_013223847.1|2096799_2097525_+|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.26113e-09

Protein sequences

>NC_017186.1|WP_013223838.1|2086712_2088017_-|GGDEF-domain-containing-protein
MDGARPAQPRTGRIRGALNPAHWILWQQRGSLIFYCFLVESVALAVTVPAAVTMPARGWDLAVFAVLASLGVLQAELGRKIERVRRLVSDTPHINLTSVWTFAGVLLLPPALVTALIAVLYLHLATRSLARMKRVPPFRMTLNATLVVITCYSAELVLDRLGVPDMYTALTAGWRGVTAITLAAVTYFLVSAITIVPALTITKRTVKAFFGGLGDNLLEVATLCLGLLTALTLATLPALAVAIVPPLLVLHRAVLIKQLEIAATTDEKTGLFNTTGWHLLASRELARAQRSTRSTFGVLMIDLDYFKLINDEHGHLAGDTVLRAVAATIKSAVRDYDSVGRFGGEEFVVLLPDIGPAAVLAVAERIRSAIESLRVEYEDGSRIRAIGGLSASIGVATYPDGGTAVDRLLQAADKALYRAKDAGRNQVVEGTAPA
>NC_017186.1|WP_176742119.1|2086041_2086644_-|TetR-family-transcriptional-regulator
MRARTFTESGRRAQIVRAAIAVIAEAGYLKASFSRIAKHAGLSSTGMISYHFAGKDDLLAACVTEIEEITGAFMQPRIDAAVGHVAQLRAYVEANVDLVGEHPAEVRALIDLIKNAGSRSDAVNGRLALFEEHFRTGQAAGAFGTFDARTAALSFTSGLDAVVATAAADVPEPAELARIGRELADLYVRATAPESTGESE
>NC_017186.1|WP_013223836.1|2085382_2086045_-|hypothetical-protein
MMIEQKTEPDAGLRRVVRANVRNVVFEVIVPMALFYGLRAAGVSQWWALMAGVLVAAPYVVWTVARNRKIDLVALVTLSVLVLSVVLGLLSDDPRTLVIREGWTAALGGLFGAWMLVTVFVGRPAQLTLGRTIAEIKRGAEGADAWAGRWDTDARFRRGLRINTAAWGAVLLGSAVVHIVLVYTLPIDLIALVTNVAWFGALALLIAWHVWYLRKENLDA
>NC_017186.1|WP_013223835.1|2084058_2085390_-|FAD-dependent-monooxygenase
MPDVLVAGAGPTGLLTAFELERAGADVLVLERDAEPTTQSKALGLQPRSVEVLADRGLLAAIEPHVRAKLPAGHFSGVPIDYTDLPTSFPYQLGVEQAHVAAAIEARLRTPVLRDAAVTAVAQDDEGVTVTAGGREHRAGWLVAADGGHSTVRTLLGADFPGSPARSSLVVADITLAVKPAGLAEDWQLPSSGSGYLLPLSEGRYRTVVFGEEQQRLERDEPVTAGEVQRALTAAHGPEILVGDVLWASRFGDASRQLERYRHGRVLFAGDAAHIHLPVGGQGLNLGLQDAVNLGWKLAATVHGTAPDGLLDSYHDERHPIAARVLVSTRAQAVLGVPDPDAVAVRAVVTELLAVPEARRAVAAELSGIGVTYPGITGRATDVPASQDGRAVLVGATVPAGWAGRVEGREGAAPRLVRPDGYVAWDGGPGLDEALRRWLGTPA
>NC_017186.1|WP_013223834.1|2081669_2083979_+|[protein-PII]-uridylyltransferase
MADGGELVKATERLLEGRHGRLGASALRAALVDLYEFWLGRGASAAGVDTAEPGVALVAVGGLGRRELVPFSDLDLLLVHNGNSGVGEIADALWYPLWDAKIGLDHSVRTPGEALKVASEDLRVAMGLLDARHLAGDAELSGRLVAAARDQWRRTARKQIPDMTASVRQRWARSGEIAQSAEPDLKHGRGGLRDFAVLEALAAAQLTARPGEELLEAKGLLLDVRTELRREIRRERDVLSAPEAELVAAELGFGDRFTLARKLSGAGRTIAYALDVALRSTVEPPKTRFGRRPSRTPLAENVVLHGNEVALARDAVPAKDPALLLRVAAASARTGKPIALGTLKALAESAPELRAPWPAEALNALVELLGAGEGLVDAVESLDRTGLWSRLFPEWGAVRDLPPRSPVHQWTVDRHLVRTCVEAAKLTTTVSRPDLLLIGALLHDIGKGRDADHSELGAKISAQVAARLGLSPADAATVSAMVRHHLLLPHTATRRDISEPATVARVVKTLDSDLVLVELLHALTQADSLATGPGVWTDWKARLLAQLAAGCEEVLHGKGFTAPEPMDDEQRELVAAAVASGTGEIRISSHGKVVTVLLAVPARAELLAPAAGVLALNSLEVHSAVLRGHDGGRAGVFTASPKFGSLPDATLLREQFARAVAGTLPLTQRLAAKERDYGPPPPVAPKVLWFDDETTGPDTVVLELRAADRIGLLFRVAGALRRCDAEVRWAKASTLGGAVVDSFAVTPRSGHIEPGWRREVEQAVLAAAS
>NC_017186.1|WP_013223833.1|2081320_2081659_+|P-II-family-nitrogen-regulator
MKLITAIVKPFTLDDVRSALEQLGVLGMTVSEVQGYGRQKGHTEVYRGAEYSVDFVAKLKVEVVTDDTNVEKVLEAITTAAHTGKIGDGKVWVTPVETVIRVRTGERGTDAL
>NC_017186.1|WP_071831524.1|2079935_2081324_+|ammonium-transporter
MLNAGDTAWVLASAALVMLMTPGLAFFYGGMVRAKSVLNMLMMNFIALAVVGVLWALYGFSMSFGDDAFGGFVGNFHFAGLENTFGKLAGFAVAATDTSPAVAWPGSDGLPILAFVMFQLMFAIITPALISGAIADRAKFWGWTLFVVVWVTVVYFPVAHWVFSFNGFVGENAVGGWIANNLKALDFAGGTAVHINAGAAGLALAIVLGKRKGWPKDTGRPHNVPFVLLGASLLWFGWYGFNAGSALAANDLAAVAFTNTTVATAAAVLGWLIVEQLKFGKPTTLGAASGAVAGLVAITPACGFVSPLGAIAIGLIAGLLCALAISLKFKFGFDDSLDVVGVHLVGGIVGTLLIGFFGTTSVNSLGADGLFYGGGFTQLGRQAAAAGAVLAYSFVLSFIIGFVIKKAGGFRVSTEDEVSGIDEAQHAESAYDFTGTGGGLGHPNTIPVKSATAATKLEESKA
>NC_017186.1|WP_013223831.1|2078913_2079612_-|rRNA-(guanine-N1)-methyltransferase
MNLLHARIPAGTADTAPMVAARADFLASGAYEPLADELARVCADAGGLVIDAGAGTGYYLARVLEASEAFGLALDVSAVALRRAARAHPRLGAAVWNLWEPWPVGDRVASVVLNVFAPRNGPEFHRVLRPGGLLVVAAPAPDHLRELGDLVLAVDERKDERLDATLGEYFTRTDRTEVRREVALTPRQVRQAVEMGPAAFHLDRDGRRERLDALHEPQTVTVSFTVSTYRRR
>NC_017186.1|WP_013223830.1|2078268_2078895_-|(2Fe-2S)-binding-protein
MKPDWTASATRLADAEWVRARIGGAAKLYGCARPEVLGTIWWYSLSSVLVGPAVEGLVAGTPVDPSLDAVELDLVADGRFLGARSTRPLDGGLPALGAALTGALGTAIATIAAVSGARERALGAIATDSIGNRLLWTPDPERAMTLAGPLVDAIDLSLPKPRFVRVGRTPAVRRASCCLIYEVGNPKCVSCPRQTPEEREARLRAALG
>NC_017186.1|WP_013223829.1|2077417_2078272_+|sigma-70-family-RNA-polymerase-sigma-factor
MDTLTERFEQERPRLRAVAYRMLGSAAEADDAVQETWLRFHRTDAGEIGNIPAWLTTVVARVCLSLLRTRRNHREEPLDGQPEPDDDRRDPGQEAELADTVGRALLVVLDALGPAERVAFVLHDMFAVPFDEIAPVIGKTPAATRQLASRARRRVKGGAPADADLPRRRKVVEAFLAASRGGDFEALLALLDPDVVLHADRFAGPTPAPVVLRGVESVRRGAILASERARASELALVDGAPGLFMVREGRLAVVLAFRVDDDRITGIDVIADPDRLAGLELAVL
>NC_017186.1|WP_014466736.1|2088607_2089360_-|glucose-1-dehydrogenase
MGARFAGKVVLVTGGGSGIGRATARAFADEGATVVVAGRDERRLASAVAEIGGGASAVTVDVTDSADVARMVATVVARHGRLDVAFNNAGILGSPAAAADLGEDDFGAVMGTNVTGMWLCLKHEVAHMRAHGGGAIVNMASNIGAHGRLPNMAAYAASKAAVSVLTRTAARDHIADGIRINAVSPGATDTDMSRRPGETDAGRAERLKNAIPLGRVGATAEVAAAVLWLASDEAAFTVGHDLVVDGGATA
>NC_017186.1|WP_013223840.1|2089383_2089971_-|TetR/AcrR-family-transcriptional-regulator
MSRVKEFDVGEACDGALTLFRRQGYEATSVSDLVTHLGVAKASLYATFGTKHDLYVTALKRYAERTDARVMAQLSEPGSGVAAVRRLFDSYTAEILGDETRMGCFVVNAAIELLPHDPEVARLVERSWDTLEVALTMALERAKAQDELPAGSDPATLARFLLTVLQGLRVLGKGTDAASRVNAAVSQAMRLLIQE
>NC_017186.1|WP_013223841.1|2090091_2090454_+|hypothetical-protein
MQDRLTLPPTVVATHLRSCAEELAAGLRCGGPGATTAELTDVVAQLVAGQEAISHALAGLAARVEGGSAALAAAPPLDVEVVTEVLRAAAIASRCSAEALDEVTPSFECVSESVSPDTRL
>NC_017186.1|WP_034286213.1|2090506_2091388_+|Ku-protein
MRAVWTGTIGFGSYAIPVKAYSATEEREIPLHQVHETDGGRVRVKRVCEVDGAEVPPEEMIRGYPVPGGDVVLLSDHELASLPMPGRTIAIRGFAPVPDVDPLWFAKSYYLEPEPAGTKPYVLFSEALQQSGRLALVTVALRRRETLGALRVRDQVIVLETMRWPDEVRTPDFPFQHADVDIRPGELRRAVNLVEELTGEFDPGRYPDRYREAFQALVQAKIDGAEVVQPTAAEQAEGVTRLLAALQESAAEAEDERNAAVTKAKAAASRAAKARTTAKRAATRSRGRTKASG
>NC_017186.1|WP_013223843.1|2091666_2092146_-|MarR-family-transcriptional-regulator
MQSEPARTLDETAARVTADAELAELSRRVREGVGRLNWRMRAEADRHIPGPAVLAVLSRLYRAGTQTPTELAEAERLQPQSLTRILASLDLRGHIERNPDPDDGRRSRVSITDEGLAVLRRYSAQRERWLATALESTLSPTERQLLRLAADLLIRVADA
>NC_017186.1|WP_013223844.1|2092155_2093934_-|ABC-transporter-ATP-binding-protein
MTAVAVLTEPATDADEPVPLRRIAALFRPHRGPLGALFALIVVQAGLGVVSPFLLREILDDALPHRDTLLISLLAAGMIVCAVGSGALGVATTGLSNTIGQRVMNELRVSVYGHLQRMSLGFFTRTKSGEVLSRVFNDIGGVDNVITTTAGSMVQNATTTIAITVALVLLDWQLAALSLVVVPLFLLFTLRLGKKRRNLARGRTRRMARLTTMVEESLSVTGVLLAKTMGNERAMRERFGAESREIASLERAAALAGRWQTASRAMSLTVIPALVYWIAGLALAGGASPISLGTVVAFTSMLNRLVAPASAMQTIGQNVATSKALFGRIFEVLDLPVEIADKPGARELQVRRGDVSMRGVSFRYGEDGPPTLREIDLDVPAGTTTALVGSTGSGKTTLAYLVARLYEVSSGSVTIDGTDIRDVTLASLAAGVGLVSQETYLFHDTVRENLRFAKPDATDDEIEQAAKAAHIHDTLAGLPEGYDTVVGQRGYRFSGGEKQRMAIARIMLRSPPVLILDEATSALDNRTERSVQAELDRLAAGRTTLMIAHRLSTVEHADQIVVLHEGRIAERGTHEELLARDGRYARLVHGST
>NC_017186.1|WP_013223845.1|2094129_2095668_+|signal-recognition-particle-protein
MFDTLSDRLTAALQTLTRKGKLSDADIDATAREIRIALLEADVALGVVKTFIAKIKERAKGAEVSQALNPAQQVIKIVNEELVGILGGETRRLNLAKTPPTVIMLAGLQGAGKTTLAGKLALWLKKQGHTPMLVACDLQRPNAVTQLQVVGERAGVVTFAPEPGNGVGDPVDVARRAIAEAKHAQHDVVVVDTAGRLGVDEELMKQAADIRDAVEPDEVLFVVDAMIGQDAVTTAQAFQDGVGFSGVVLTKLDGDARGGAALSVREVTGQPILFASNGEKLEDFDTFHPDRMASRILGMGDVLTLIEQAEQAFDQKQAEKAAEKLSSGQLTLEDFLEQMLAVRKMGPIGNLLGMLPGAGQMKDQLAQVDDKHLDKLQAIIRGMTPAEREDPKMINGSRRLRIANGSGVTVREVNDLVNRFFEARKMMAQMAGRFGFGGGGGSSKRKGKKGKKGGRGPTQPKVRGGFPGGMPMLPPGGQMPGGMPDLSQLGGMNDVPGFDPTKFKLPKNPKDN
>NC_017186.1|WP_013223846.1|2095676_2096753_+|amidohydrolase-family-protein
MEKTLHAAGVILPGGEPRELWITGGRISFEPVEDAESLGRDVFLVPGLVDAHCHPGIGVGGPVSLEEAADQAITDRNAGTLLIRDCGLPIDVRPLQRRADLPAIIRAGRHLALTKRYLPGLGIELDDPAQLPEAVAEQARAGDGWVKLVGDWIDRGVGDLAPLWPDDVLAEAVKVAHDLGARVTAHVFGEAALPGLIAAGIDCLEHGTGLSADQLAELARHDVALVPTLINIENFPGIADKAGKYPAYAAHMRALHAGVGEMVASAIEAGVRVFAGSDAGGMVEHGRLVDEIEALHRAGMTREQALASASWGARDWLGHPGLDDGAPADLLVYPSDPREDLGVLRHPSHIVLGGVVYA
>NC_017186.1|WP_013223847.1|2096799_2097525_+|CPBP-family-intramembrane-metalloprotease
MTDDDGARRVLGAHWCFVAFFAGIAGYYLANLIIAAAVNRNVGEFDPLELHDIGPLLLLAFVPNLLLGLGPAAGSWRWGEGLRTDFGLVPTWRDVRIGLACGVLALVVGYLLNLMLIAVYGADDVSDSPLTDLADTFDGDTVWLVLAAVIVIAGAPITEELLVRGTLWNALWFHRVPPWAVLVLTSLVFAQLHGEPTRTIALFGQGIAMGLARYLSGRVSAGVIAHAANNLPPAVLLFVAH
>NC_017186.1|WP_013223848.1|2097626_2098430_+|CPBP-family-intramembrane-metalloprotease
MTTSQPRDPAPDATPFPEPEEAAATAFLPPVPRHRWGFGAFLLVEGVLLASAAFVSVLVGNTGPGPLPMRVVLLGTMLPTMIAAGVAVLITFVRGNGPLSDLRLEWRWADVKTGFRYGCVGLVFTTLAAYLWTRLVGDANATSAISALVEDRRMSVSAALVMFVYLWLLGPICEEIIYRGLLWGAAEQLQWRSERWGRVAAFLLSTAVFAASHLEPLRTTLLLVIAVPIGLVRLVTGRLPGSIVAHQVNNFLPALTILLGALGVASF

Crispr_ID: NC_017186_9

• CRISPR_ID: NC_017186_9
• CRISPR_location: 2551218-2551314
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_9

Consensus_repeat	Method
GCTGCACCGCTGCGGTGATGGCCGGTGT	CRISPRCasFinder

spacers of NC_017186_9

>9.1|2551246|41|NC_017186|CRISPRCasFinder
CGGCTCGAAGCGCGGGCAGCGCCCAAGTAAGCAGGCCTTGC

CRISPR arrays and Neighbor proteins around NC_017186_9

CRISPR arrays

The CRISPR arrays of NC_017186_9

>merge|NC_017186|9|2551218-2551314|CRISPRCasFinder
GCTGCACCGCTGCGGTGATGGCCGGTGTCGGCTCGAAGCGCGGGCAGCGCCCAAGTAAGCAGGCCTTGCGCTGCACTGCTGCGGTGATGGCCGGTGT

>NC_017186|9|8|2551218-2551314|CRISPRCasFinder
GCTGCACCGCTGCGGTGATGGCCGGTGT	CGGCTCGAAGCGCGGGCAGCGCCCAAGTAAGCAGGCCTTGC
GCTGCACTGCTGCGGTGATGGCCGGTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013224274.1|2562124_2563102_+|neutral-zinc-metallopeptidase	unknown	unknown	gnl|CDD|225203
NC_017186.1|WP_013224266.1|2551836_2552331_+|transcriptional-repressor-NrdR	unknown	unknown	gnl|CDD|234774
NC_017186.1|WP_013224261.1|2546538_2547042_+|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238042
NC_017186.1|WP_013224256.1|2539400_2540714_-|DUF349-domain-containing-protein	unknown	unknown	gnl|CDD|377186
NC_017186.1|WP_034284350.1|2563094_2563667_-|TIGR03086-family-protein	unknown	unknown	gnl|CDD|274424
NC_017186.1|WP_013224262.1|2547084_2548533_+|GTPase-HflX	unknown	unknown	gnl|CDD|225171
NC_017186.1|WP_013224263.1|2548585_2549602_+|hypothetical-protein	unknown	unknown	gnl|CDD|379191
NC_017186.1|WP_013224269.1|2556580_2558248_-|hypothetical-protein	unknown	unknown	gnl|CDD|143636
NC_017186.1|WP_013224267.1|2552361_2555175_+|vitamin-B12-dependent-ribonucleotide-reductase	unknown	unknown	gnl|CDD|235828
NC_017186.1|WP_085931698.1|2559998_2562020_-|S9-family-peptidase	unknown	unknown	gnl|CDD|224422
NC_017186.1|WP_013224259.1|2542698_2545212_-|valine--tRNA-ligase	unknown	unknown	gnl|CDD|380147
NC_017186.1|WP_013224265.1|2550693_2551158_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|366664
NC_017186.1|WP_013224257.1|2540932_2541844_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl|CDD|234626
NC_017186.1|WP_071831492.1|2559170_2559800_+|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224103
NC_017186.1|WP_013224270.1|2558409_2559156_+|ferritin-like-domain-containing-protein	unknown	unknown	gnl|CDD|153097
NC_017186.1|WP_013224272.1|2559799_2560009_+|multidrug-SMR-transporter	unknown	unknown	gnl|CDD|224987
NC_017186.1|WP_049878229.1|2549675_2550335_-|transcriptional-repressor-LexA	unknown	unknown	gnl|CDD|234688
NC_017186.1|WP_013224258.1|2541854_2542682_+|diaminopimelate-epimerase	unknown	unknown	gnl|CDD|234768
NC_017186.1|WP_013224268.1|2555243_2556584_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013224260.1|2545221_2546475_-|MFS-transporter	unknown	unknown	gnl|CDD|340863

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013224274.1|2562124_2563102_+|neutral-zinc-metallopeptidase	gnl|CDD|225203	COG2321, COG2321, Predicted metalloprotease [General function prediction only].	3.57513e-19
NC_017186.1|WP_013224266.1|2551836_2552331_+|transcriptional-repressor-NrdR	gnl|CDD|234774	PRK00464, nrdR, transcriptional repressor NrdR.	2.60186e-77
NC_017186.1|WP_013224261.1|2546538_2547042_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.16084e-07
NC_017186.1|WP_013224256.1|2539400_2540714_-|DUF349-domain-containing-protein	gnl|CDD|377186	pfam03993, DUF349, Domain of Unknown Function (DUF349). This domain is found singly or as up to five tandem repeats in a small set of bacterial proteins. There are two or three alpha-helices, and possibly a beta-strand.	7.73551e-16
NC_017186.1|WP_034284350.1|2563094_2563667_-|TIGR03086-family-protein	gnl|CDD|274424	TIGR03086, TIGR03086, TIGR03086 family protein. This family, like pfam07398 and TIGRFAMs family TIGR030834, belongs to the larger set of probable enzymes defined in family TIGR03083. Members are found primarily in the Actinobacteria (Mycobacterium, Streptomyces, etc.). The family is uncharacterized.	2.93763e-34
NC_017186.1|WP_013224262.1|2547084_2548533_+|GTPase-HflX	gnl|CDD|225171	COG2262, HflX, GTPases [General function prediction only].	9.96662e-170
NC_017186.1|WP_013224263.1|2548585_2549602_+|hypothetical-protein	gnl|CDD|379191	pfam13449, Phytase-like, Esterase-like activity of phytase. This is a repeated domain that carries several highly conserved Glu and Asp residues indicating the likelihood that the domain incorporates the enzymic activity of the PLC-like phospho-diesterase part of the proteins.	0.00106286
NC_017186.1|WP_013224269.1|2556580_2558248_-|hypothetical-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.66194e-05
NC_017186.1|WP_013224267.1|2552361_2555175_+|vitamin-B12-dependent-ribonucleotide-reductase	gnl|CDD|235828	PRK06556, PRK06556, vitamin B12-dependent ribonucleotide reductase; Validated.	0
NC_017186.1|WP_085931698.1|2559998_2562020_-|S9-family-peptidase	gnl|CDD|224422	COG1505, COG1505, Serine proteases of the peptidase family S9A [Amino acid transport and metabolism].	0
NC_017186.1|WP_013224259.1|2542698_2545212_-|valine--tRNA-ligase	gnl|CDD|380147	NF000540, alt_ValS, valine--tRNA ligase.	0
NC_017186.1|WP_013224265.1|2550693_2551158_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|366664	pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.	1.3559e-06
NC_017186.1|WP_013224257.1|2540932_2541844_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl|CDD|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	8.51543e-144
NC_017186.1|WP_071831492.1|2559170_2559800_+|NAD(P)H-dependent-oxidoreductase	gnl|CDD|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	6.01115e-37
NC_017186.1|WP_013224270.1|2558409_2559156_+|ferritin-like-domain-containing-protein	gnl|CDD|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	1.26159e-05
NC_017186.1|WP_013224272.1|2559799_2560009_+|multidrug-SMR-transporter	gnl|CDD|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	2.792e-05
NC_017186.1|WP_049878229.1|2549675_2550335_-|transcriptional-repressor-LexA	gnl|CDD|234688	PRK00215, PRK00215, transcriptional repressor LexA.	1.75616e-112
NC_017186.1|WP_013224258.1|2541854_2542682_+|diaminopimelate-epimerase	gnl|CDD|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	8.59427e-102
NC_017186.1|WP_013224260.1|2545221_2546475_-|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.11331e-61

Protein sequences

>NC_017186.1|WP_013224265.1|2550693_2551158_+|LysM-peptidoglycan-binding-domain-containing-protein
MSILAERGHVRPATPVPAPLRPVRVLRGRRGEVHRPPTRARVVAGRRPAGAPCAAPRRVPVRWPWLAALAVASCLVVTGLGLFGGGAPGAPVPERTATVSVEQGDTLASLAARFAPESEPGAVVARIKELNRLDQAVLVPGLPLTVPVADVPAP
>NC_017186.1|WP_049878229.1|2549675_2550335_-|transcriptional-repressor-LexA
MPEVYDVDETLTVRQQQVLDVIRSWVSRFGYPPSVREIGEAVGLTSTSSVSHQLRALQRKGYLRRDANRPRAVGVLSATDDNPMGIEMDQQPVMPKAAYVPLVGRIAAGGPVLAEQAIEDVFPLPREIVGEGELFLLKVTGDSMIDAAITDGDWVVVRQQPDADNGEIVAAMIDGEATVKTFKRKGGHIWLMPHNEAYEPIPGDDATVLGKVVAVLRRL
>NC_017186.1|WP_013224263.1|2548585_2549602_+|hypothetical-protein
MRWVVALVFLAVFSGSVPASAAPAAPEPLCTVKDPRIDELSGLVSDGAKLYAINDGGSKVQVFVLGRDCKVQKVLTDKTDPFDVEDLARTPDGRLWLSDTGDNKMGRLTVALLEMSPEGKVTLHRLTYPDGQHDTEALIMDKAGTPYLITKDILGEAGVYRPSGPLASPGPTNLEKVGTVKIATTDTQGGPVGSIGSVLVTGGASTADGSVIALRTYTDAYLYAAPDGDVPAALQRTPVRIPLPGEKQGEAIAFDPDGTLLSGSEGVGQPLRAVRGAAASAAQSGAPAKGTTSTATGASAGSAEDGSGLPILPAAGITVAVVGLGWFGFSRLRRRTRR
>NC_017186.1|WP_013224262.1|2547084_2548533_+|GTPase-HflX
MTELTHTEDHDDDLYDGDPSTGEMELEDRASLRRVRGLSTELDDVTEVEYRQLRLERVVLVGVWTEGTALQSEASLAELARLAETAGSEVLEGLIQRRTKPDPATYIGSGKVRELRDIVGSTGADTVICDGELSPGQLRQLEEKVKVKVIDRTALILDIFAQHARSKEGKAQVELAQLQYLIPRLRGWGASLSRQAGGRAGGANGGVGLRGPGETKLETDRRRINKRVAKLRREIAAMDTIRETKRGRRLANEVPSVAIVGYTNAGKSSLLNALTGAGVLVEDALFATLDPTTRRAQTPDGRGYTLTDTVGFVRHLPHQLVDAFRSTLEEAADADLLVHVVDGSDPAPEEQVSAVREVLGEITRKRKEPLPPELLVINKTDASDEVSLARLRHALAGSVQVSARTGAGIAELVEVIADRLPRPEVTVDVLVPYSRGELVARAHADGEVLEEEHAEDGTRLLVRVRPDLAAALREYETNSTRA
>NC_017186.1|WP_013224261.1|2546538_2547042_+|winged-helix-turn-helix-transcriptional-regulator
MLPAKRRAATEAEAAALASGIRLRIIRLTFSEALTNKELAERLGRDPATTLHHVRRLVETGFLAAQPPRRGARGAKEIPYLSTGLSWTLDSCGDKDVEQAVLEAYLAEIAETGFEGVHQSRLVVQVAPEERAELETRLNALLEEFQSRPRRPGAERTAIYLATYPST
>NC_017186.1|WP_013224260.1|2545221_2546475_-|MFS-transporter
MHRGSLFRHADFRRLWAGDTASQFGVFVGTTAVPLLAAVTLAATPFEMGLLTAAETIAFLLIGLPAGVWVDRLRRRRVMLTADFTRFALLLSVPVSWWAGVLTLAQLLVVALFVGIATVFFDIAYQSYLPSLVGREHLLEGNAKLQAVQSTAQIAGPSAAGVLVQLVTAANTVLVTSAGFLTSALCLLRIRTVEPEPERGGHARLAPQIAEGLRFVFSDKPLRAIVGTTATANCFGGAFTAVQVLFLTRTVGLPPAAVGVLLAVGGAGGILGALCSGALTRRIGQARAIWLVPLCTMPGHLLIPLAAPDWRLGLAAFGAVAGGFGIIVYNVAQVTYRQAICPERLLGRMNASVRFVVWGTIPLGGLLGGALGEGLGLRGAMWVAVAGEVAAVLWVVCSPLRHLRDLPTEAKSGSGAA
>NC_017186.1|WP_013224259.1|2542698_2545212_-|valine--tRNA-ligase
MSTPYERPRVPDKVGVDGLEAKWVPVWESSGAYRFDRTKTRDEVYSIDTPPPTVSGSLHIGHVFSFTHTDVLARFKRMRGLEVFYPMGWDDNGLPTERRVQNHFGVRCEPSLPYDPDFRPPEKPGKDVVAISRRNFVELCESLTETDEQAFERLWRQLGLSVDWTMTYQTIGHDSRLISQRAFLRNLERGEAYQAEAPTLWDVSFRTAVAQAELEDRERPGAFHDLAFTGPDGADVVIATTRPELLPACVALVAHPDDERFKPLFGKTVRTPVFGVEVPVVAHHLADPEKGRGIAMVCTFGDTTDVTWWRELRLATRVVLGRDGRFLPDAPSGVPAEAYAPLVGKTVHTGREIMVRLLRDAGALRGEPRPITHSVKFYEKGDKPLEIVASRQWYLRNGGNDEAFRKKMLARGEELNWVPKHMRVRYSSWVENLAGDWLISRQRFFGVPIPLWYRLDSAGEPDYDARLLPDTLPVDPSSDVPPGFTEEQRGVPGGFAADPDVMDTWATSSLTPQIVGRWSIDDDLFSRVFPMDLRPQAHEIIRTWLFSTAVRAELEHGVLPWREASIAGWVLDPDRKKMSKSKGNVTTPVDLLERFGSDAVRYWAASARPGVDTAVDEGQMKVGRRLATKLLNASRFVLGLGVPMPGAAATEPLDRALLASLAVVTGQATAALEASDYARALQVTETFFWTFCDDYVELVKGRAYGDRGPDAAQSARAALVTALSALLRLFAPFLPFATEEVWSWWRSGSVHLAAWPSVAESDGDPELLSLAGHVIAAVRRAKTDAKVSMRSAVETLTVTGPAEVLERFTAIEPDIRTAGAISSVETREGDFAVEAEV
>NC_017186.1|WP_013224258.1|2541854_2542682_+|diaminopimelate-epimerase
MGGIEFLKGHGTQNDFVLLPDPAGRLELTEARVAALCDRRRGLGADGVLRVVRAAELGEPSAGEWFMDYRNADGSIAEMCGNGVRVFARYLVETGLAAEGEFVVGTRAGDRPVVVHPDRSVTVHMGPATITGTSVTVVAGRPFSGVAVDVGNPHLVSLLDDDVAGLDLREQPDFDHDLFPHGVNLEFINCLGEGALRMRVHERGVGETRACGTGTVAAVAAAFHLAGTDTGASTVDIPGGRVEVTVSRGASTLSGPAEIVARGELDEAWWVAAGS
>NC_017186.1|WP_013224257.1|2540932_2541844_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MNSPAVPVAVVGPTATGKTALAVDLACALGGEVVNADAMQLYRGMDIGTAKATEAERRGVPHHLLDVLDVTETASVAAYQRHARAEIERLLADGRVPVLAGGSGLYVQAVLDDLRFPGTDPAVRARLDAEAEQLGTPALYTRLGERDPVAAAKILPTNTRRIVRALEVIEITGEPFSANLPEPGPARYGTVVIGVDRAPEELDERVNERVGRMFEAGLVDEVRELEKRGLREGKTASRALGYQQVLAELDGDGDFAAAAAATAQATRRFVRKQRSWFRRDQRIHWFDGADPGLAARVLDTLAR
>NC_017186.1|WP_013224256.1|2539400_2540714_-|DUF349-domain-containing-protein
MAQENTSTGTPAPHPVPHALHAGHAAPPVPPAEPTPAIWGRIDDEGTVYVLTAEGERAVGVWQAGTPDEGLVHYARRFDDLRTEVELLETRLISGAGDPKHALSSATQIRDGLAEAAVVGDLAALAARLEYVIGHAEKALASAKAEREEARAAAVARKQELAEEAEKIAAESTQWKAAGDRLRAILDEWKTVKGVDRKTDDELWKRFSKAREAFNRRRGSHFAELDKQRASAKQRKEELIAEAEAISESEDWGDTAGRYKDLMTEWKAAGRAPKDSDEALWQRFRAAQDKFFARRSAVFSERDAEFTQNAARKEELLIEAEKIDAAANLEAAKSALRRIQEQWDEIGKVPRERIRELDGRLKAVQDAVKSAEDNRWRKTDPEAQARAAQFRERVEQYETQAAKARAAGDERRAKKADEQAAQWREWLQAAEAAVADR
>NC_017186.1|WP_013224266.1|2551836_2552331_+|transcriptional-repressor-NrdR
MRCPFCRHADSRVVDSREVDEGQAIRRRRSCASCGRRFTTSETMVLAVVKRSGVTEQFSRDKVVSGVRRACQGRPVDDDALQQLAQRVEESIRSAGLAEIPSHEVGLAILGPLRELDGVAYLRFASVYRSFSSVEDFEKEIADLREAMAGSVAHEESDQREDGD
>NC_017186.1|WP_013224267.1|2552361_2555175_+|vitamin-B12-dependent-ribonucleotide-reductase
MTETVGTGARAAAGKKGKTAGGLSVQRVFTTEGQHPYDQVTWEQRDVVMTNWRDGSVNFEQRGVEFPDFWSVNATNIVTSKYFRGAVGSPQRERSLKQLIDRVVHTYVKAARDHGYFAAPQDLEIFEHELTWMLLHQVFSFNSPVWFNVGTPSKQQVSACFILAVDDTMESILNWYREEGLIFKGGSGAGLNLSRIRSSKELLTSGGTASGPVSFMRGADASAGTIKSGGATRRAAKMVVLDVDHPDIEEFIQTKAREEKKIKVLRDAGFDMDLSGADISSVQYQNANNSVRVTDEFMQAVENGTEFGLRARLTGEVIDRTDAKKLFRTMAQAAWECADPGIQYDGTINDWHTCPESGRITASNPCSEYMHLDNSSCNLASLNLLKFVTPEGTFDAPLFARAVEFVITAMDVSICFADFPTEPIADTTRKFRQLGIGYANLGALLMALGHAYDSEGGRALAAAITSLMTGVSYRRSAEMARVVGAYEGYARNAEAHQRVMRKHAAANELVRTYHSNDAAVRALATEEWQKGIEIGAKHGWRNAQASVLAPTGTIGFMMDCDTTGIEPDFSLVKFKKLVGGGSMQIVNQTVPRALEALGYLTEQVEAIVEYVAQNGHVVDAPGLRPEHYEVFDCAVGERSIAPMGHVRMMAAVQPFLSGAISKTVNMPESATVEEVEEIYFQGWKLGLKALAIYRDNCKVGQPLSTAKKESAAAEPEKVVEYRPVRKRLPKKRPSQTVSFTVGGAEGYLTAGSYPDDGLGEIFVKLGKQGSTLAGVMDAFSMSISVGLQHGIPLEFYVSKFCNLRFEPAGMTDDPDIRIATSVMDYLFRRLALDYLPYEKRSQLGILSADERSAEVEATYGNPGVDLEALQSTVDASPEPHADEPEHPHREARTTTELMELRLGKAADAPLCMTCGTKMRPAGSCYACEGCGATSGCS
>NC_017186.1|WP_013224268.1|2555243_2556584_-|hypothetical-protein
MNSLKERIGSHAEACTKRALKHYGNVLRTALADGQFPMRVDSLVAVLRTATKGDSARYDDELVPYVGALVEILANVGRGNQPHREEGLIELFETTLTQLHARGNRTTDIRLLLARYSAALSNGGRRRLEIIRSAISESRDADEKLRAVLVLAKYHIDISDYDAAFRYLDECEALAEEAGTGRFEIYDVHTTRGIALFYNNIRLARHSLARGVSCELASSSPAVCRATASALHYLGRIQATRGDHRGALTHVVAAQHIKDTLNPESGQLGFFHLRTGEILLAAGNTSAGKDHLREAGRLFHDVHSRSTAEAQLNSTLAGVAAAEGNTAAAEKLLHEALASARRDNYPRGELLFSLQIFLLQLRRGTLIAAVKTATGVIGVVRRTEPGEWRWIFRRVRVSSFAFLLAFLRPGKRAEPPSPPQCPCPIHRNVPLAELLDEVKAALPPTT
>NC_017186.1|WP_013224269.1|2556580_2558248_-|hypothetical-protein
MIDVEGYGAHRRTNRHRIAIRQGVHELTEAAFAAAGIPWERCDCRDLGDGLLILAPPEIPKSDIVDAMPDQLAAAVSAHNASAAPEEQVRLRAAIHAGEVTYDDHGVVGAAVNFTFRLCDSPALKSELATAPGVLAVIVSSWIYDEVVRHGPPERVTRYRERAVAVKETNTVGWIQLPGQGGSSPASPPTRVDQFESWQYKAYVNHDQLFGTDKLIDIIVRSTGNVLADQVTSIVGAGGIGKTAIAYEAVRELRRRGHFTKVAWTSAANPQATGCSVTTEGFTTVYWLELLRDLAAQLDFDLGPSRTLWESEFARQVAGLPSGDQLLVVVDNLETLPDATDAVGRLRRMGVFKPHALLVTTRWELQSHLPDIAEFRVRPLSPEDSVLFIKHLSMADPDLQEAGDRALAPILDATEGNPFLIKLAVQQYLSSHRPLDHVLRDLRDLRAASGGGEGLAETARSYLYTASLQELERRRGTADADALLASFCVKGRGDSFHYDELEQISGIQPAAGFLATLSTACQLSIVTSFGDGSIDQLRRRYTIHSLLYDFTCGMS
>NC_017186.1|WP_013224270.1|2558409_2559156_+|ferritin-like-domain-containing-protein
MTYAHWLQDFETEAERRSQREDPPWERGAKLHPDVAKSIQRFQVGEAGDGANLIAKAAGDDTYLAAVKLFVAEEQNHARMLAGLLAAAGVPTIAKHWSDTVFVKLRRALGLRLELMVLLIAEVVALRYYRALRDGGGDPLVTQVAARILADEERHVPFHCHRLEVAFRELAKPARAAVFGAWRVLLLGVAATVAADHGAALRRLGVGRLVFVADVLTAFEAALARIRGEQPKPGPRYIPKRARPRGLF
>NC_017186.1|WP_071831492.1|2559170_2559800_+|NAD(P)H-dependent-oxidoreductase
MPQGRGDPLRRHLDSSARRSSFSRELSARYSATWTGTRTYRDLAADPVPVIGEAWTEICDALLAAGITDPAHYAGVVGTPSQKQAWAIVEPLLAELLEADVVLIGAPMYNFSIPAALKAWIDQVTFPRMSLRPKKFVIAGARGGTYAEGTPRAPFDHHERYLRDFVAGHYDVDDVRFVHAELTNALVDPHLAAREGERVASREAALAAI
>NC_017186.1|WP_013224272.1|2559799_2560009_+|multidrug-SMR-transporter
MGWVTLVLAGFVEIAWSQSVKPTENFTKPWPTLLCFVLGVVVTKDPLSVGRVAALALIVGGVVLARVTS
>NC_017186.1|WP_085931698.1|2559998_2562020_-|S9-family-peptidase
MSGMSVEDPYLWLEDVTGDDALGWVRARNDETLAELTAGARFAELRDELREVLDADDRIPYVRRRGEFLYNFWQDASHPRGLWRRTTLESYRQAEPEWELLLDVDALAEAEGENWVWQGATVLRPGYRRGLVELSRGGADATVVREFDLDAHEFVADGFTVPEAKTRIGWIDLDRVYIGTDFGPGSLTSSGYPRLAKEWRRGTPLEAATTVFEGKPDDVSIGASHDPTEGFERDFVSRAIDFYRSELHLRTPGGLVKIDVPDDASASLHREWLLVRPRTAWTVGGTEHPAGALIAIIFDAFMAGDRDFTTLFTPDEHTSLSYWAWTRHHLLLGTLRDVRTELRTLTPGPDGWQEAPLAGGPEFGSADIFDTDPDVSDEYLIDSSGFLQPSTLSYGHVGEEVEVLKQAPAFFDASDMSVAQYFATSEDGTKIPYFVVRPSGAEGGPTLLTGYGGFEVSLTPSYSGMIGRGWLARGGTYVVANIRGGGEYGPGWHTQAIKAERHRVYEDFAAVAADLVERGITTPAKLGIQGGSNGGLLMGVMLTRYPERFGAIVSQVPLLDMRRYHLLLAGASWMAEYGDPDDAAEWDYIAKYSPYQNVHSGRAYPPSLFVTSTRDDRVHPAHARKMVARMREQGHDVRYHENIEGGHGAAADNEQLAFKWALVFEFLWEQLTK
>NC_017186.1|WP_013224274.1|2562124_2563102_+|neutral-zinc-metallopeptidase
MNDAEPPWPGTARPPEPAWTPEPSPWTPGWAAAPPVPIAPPRNRLWGAVTGVLIVVVAMSLIAATIPHRVDGRALAAQGADSGRAYGGTGKPPKAVPELARNPLLGDGISPGPATCSLPELGRAADQLKAYYGALVSCLEQSWRPALEKVNEPTLTATVSVTLPEHSSCGEAPTENEAVAYYCGGDTTIYAPTDWMLSDAGLNKARHIATLAHEYGHHVQRESGILSAAADKMTSPDENSAADKEVVRRIELQANCFGALFLTAVAGPGSISRSLANAAVADYGRANNSDTHGSREHQLSWAKAGYDGKATKACDTWSAPVGEVS
>NC_017186.1|WP_034284350.1|2563094_2563667_-|TIGR03086-family-protein
MDLRELDRRTLLILDKLVAGVTSADLARPTPCAGWTLADLLRHQVSENHAFATAAREGSAPDWDAGVLGDDAYAAYRASVDDFLDAFTDDAVLERQLTINHFGTFPGSIAAHMHLVDTLAHGWDLARTLDLPYEPDAEAVYIASKLAERIPDEGREKNGSFAHSVEVPAGASELDRFLALLGRDPAWRVS

Crispr_ID: NC_017186_10

• CRISPR_ID: NC_017186_10
• CRISPR_location: 2899104-2899190
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_10

Consensus_repeat	Method
GCCCGGCCTGGCGAGCACTCTCCGGCCGG	CRISPRCasFinder

spacers of NC_017186_10

>10.1|2899133|29|NC_017186|CRISPRCasFinder
GTCCGATCGCCCGGGCGCTCAGCGGTGCC

CRISPR arrays and Neighbor proteins around NC_017186_10

CRISPR arrays

The CRISPR arrays of NC_017186_10

>merge|NC_017186|10|2899104-2899190|CRISPRCasFinder
GCCCGGCCTGGCGAGCACTCTCCGGCCGGGTCCGATCGCCCGGGCGCTCAGCGGTGCCGCCCGGCCTGGCGAGCACTCTCCGGCCGG

>NC_017186|10|9|2899104-2899190|CRISPRCasFinder
GCCCGGCCTGGCGAGCACTCTCCGGCCGG	GTCCGATCGCCCGGGCGCTCAGCGGTGCC
GCCCGGCCTGGCGAGCACTCTCCGGCCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013224589.1|2908947_2910213_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223489
NC_017186.1|WP_013224577.1|2896150_2897527_+|replication-associated-recombination-protein-A	unknown	unknown	gnl|CDD|237355
NC_017186.1|WP_013224574.1|2893282_2894011_-|metallophosphoesterase-family-protein	unknown	unknown	gnl|CDD|378975
NC_017186.1|WP_013224580.1|2899417_2899804_+|DUF948-domain-containing-protein	unknown	unknown	gnl|CDD|377605
NC_017186.1|WP_013224573.1|2892444_2893311_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238870
NC_017186.1|WP_013224576.1|2895312_2896008_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_017186.1|WP_014466857.1|2889855_2890803_+|DUF389-domain-containing-protein	unknown	unknown	gnl|CDD|377221
NC_017186.1|WP_013224572.1|2890882_2892064_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013224570.1|2888080_2889856_+|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775
NC_017186.1|WP_013224579.1|2898087_2898933_+|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224995
NC_017186.1|WP_034284342.1|2902831_2903332_+|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl|CDD|335420
NC_017186.1|WP_071831604.1|2905597_2906452_+|shikimate-dehydrogenase	unknown	unknown	gnl|CDD|234703
NC_017186.1|WP_013224588.1|2908431_2908848_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013224587.1|2907746_2908406_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|380060
NC_017186.1|WP_013224578.1|2897672_2898050_+|VOC-family-protein	unknown	unknown	gnl|CDD|380093
NC_017186.1|WP_013224586.1|2906515_2907796_+|GrpB-family-protein	unknown	unknown	gnl|CDD|377252
NC_017186.1|WP_013224581.1|2899800_2900106_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013224575.1|2894073_2895282_-|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NC_017186.1|WP_013224582.1|2900178_2902839_+|alanine--tRNA-ligase	unknown	unknown	gnl|CDD|234701
NC_017186.1|WP_013224584.1|2903328_2905608_+|endolytic-transglycosylase-MltG	unknown	unknown	gnl|CDD|224475

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013224589.1|2908947_2910213_-|alpha/beta-hydrolase	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	2.20403e-06
NC_017186.1|WP_013224577.1|2896150_2897527_+|replication-associated-recombination-protein-A	gnl|CDD|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NC_017186.1|WP_013224574.1|2893282_2894011_-|metallophosphoesterase-family-protein	gnl|CDD|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	3.16595e-17
NC_017186.1|WP_013224580.1|2899417_2899804_+|DUF948-domain-containing-protein	gnl|CDD|377605	pfam06103, DUF948, Bacterial protein of unknown function (DUF948). This family consists of bacterial sequences several of which are thought to be general stress proteins.	2.69217e-13
NC_017186.1|WP_013224573.1|2892444_2893311_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	2.28834e-42
NC_017186.1|WP_013224582.1|2900178_2902839_+|alanine--tRNA-ligase	gnl|CDD|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NC_017186.1|WP_014466857.1|2889855_2890803_+|DUF389-domain-containing-protein	gnl|CDD|377221	pfam04087, DUF389, Domain of unknown function (DUF389). Family of hypothetical bacterial proteins with an undetermined function.	3.44991e-30
NC_017186.1|WP_013224570.1|2888080_2889856_+|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NC_017186.1|WP_013224579.1|2898087_2898933_+|NAD(P)-dependent-oxidoreductase	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	5.55739e-62
NC_017186.1|WP_034284342.1|2902831_2903332_+|Holliday-junction-resolvase-RuvX	gnl|CDD|335420	pfam03652, RuvX, Holliday junction resolvase. This family of nucleases resolves the Holliday junction intermediates in genetic recombination.	1.47778e-48
NC_017186.1|WP_071831604.1|2905597_2906452_+|shikimate-dehydrogenase	gnl|CDD|234703	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed.	8.86546e-88
NC_017186.1|WP_013224587.1|2907746_2908406_-|TetR-family-transcriptional-regulator	gnl|CDD|380060	pfam17931, TetR_C_23, Tetracyclin repressor-like, C-terminal domain. This is a C-terminal domain present in putative TetR family transcriptional regulators found in bacteria.	1.14366e-41
NC_017186.1|WP_013224578.1|2897672_2898050_+|VOC-family-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.33712e-21
NC_017186.1|WP_013224586.1|2906515_2907796_+|GrpB-family-protein	gnl|CDD|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	4.35448e-70
NC_017186.1|WP_013224575.1|2894073_2895282_-|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.22481e-85
NC_017186.1|WP_013224576.1|2895312_2896008_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.71549e-14
NC_017186.1|WP_013224584.1|2903328_2905608_+|endolytic-transglycosylase-MltG	gnl|CDD|224475	COG1559, COG1559, Aminodeoxychorismate lyase [Coenzyme transport and metabolism].	1.88535e-76

Protein sequences

>NC_017186.1|WP_013224579.1|2898087_2898933_+|NAD(P)-dependent-oxidoreductase
MTVAFLGTGIMGAPMAANIAKAGLDVRVWNRTREKAEPLSDVAAVADSAASAADGADTLVTMLADGPAVAEAFEAASPASGTLWLQMSTVGLDWTDRLAALAEQAGVVFVDAPVLGTRQPAEQAQLQVLASGPEEARPKATPVFDAVAIKTQWLGPAGNGSRLKLVLNAWVLALTNGTAESLGLARALGLDPALFLETIEGGGLDVGYAHVKGGAMLSGEYPPAFPAALAAKDARLVVEAAAEDVDVAGAKAALAHLEAAVEAGHGDEDMAALYRAVVKER
>NC_017186.1|WP_013224578.1|2897672_2898050_+|VOC-family-protein
MPATLQCIVLDCPEPLVLARFYQALLGGEVDRPDPRWRVDEDWSTLHVGGLVLGFQRALDHQPPRWPDPAFPQQFHLDFEVDDFRESHEVVLANGGRLLDPDLGGRGWRVYADPAGHPFCLLGDY
>NC_017186.1|WP_013224577.1|2896150_2897527_+|replication-associated-recombination-protein-A
MAQDELFTVNADIAPPPERTTSNAGAEPQADPASSPLAVRMRPRSLGEVVGQQHLLREGAPLRRLVEGAAPASVLLYGPPGTGKTTLANLVSIATGRRFVAMSALSAGVKEVRGVIEEARRRRQYNAENTVLFIDEVHRFSKTQQDALLGAVEDRTVLLVAATTENPSFSVVSPLLSRSLVLQLRPLTDEDITALLERALADERGLGGELTLTEDARAHLVRLAGGDARRALTALEAAADAASATEAKTIDLPIVESTVDKAAVRYDRDGDQHYDVISAFIKSIRGSDVDAALHYLARMIEAGEDPRFLARRLVVHASEDIGMADPTALQSAVAAAHAVQFIGMPEGRLALAQATVHLATAPKSNSVIKGIDAALADVRAGLAGTVPPHLRDGHYAGAKKLGNAQGYRYPHDVPEGVLAQQYPPDELVGRDYYEPTQRGAERPLAERVPKLRRTIRGQ
>NC_017186.1|WP_013224576.1|2895312_2896008_-|TetR/AcrR-family-transcriptional-regulator
MSHPNRERADRILDAAGELLLRMGYRKVAIDDVARAVGIGKGTVYLHWRTKELVFQALMMRESADLTDELLAAIKADPAMILPHRMIPGSFLITHRRPLVMAILRGNAEILGSLGDVALKKQQDELGVRFEEVMLRHGLIRADVPHLNFALHAATLGFYLGDTLSDEFEGIPLQEKADVLAHLIRTAFEPPGEPDPVAVAAVAAELSSALEELVSGYRHGIYAHDPAKAPG
>NC_017186.1|WP_013224575.1|2894073_2895282_-|cytochrome-P450
MTTTMADTWGLHEAQFWLRGKQPEKRVEFAAELGMWNVYGHPEIETILRDPAAFSSDTTRLVPKELMPDPDYDMSTGSILQLDPPLHNKMRKLVSRAFTPKVVADLEPRIAAITRELLDAIPAGDRLELVEHLAYPLPVIVIAELLGVPAGDRNLFKGWVDKMFESANQVSLVKKDDKQDAAILASLEGQKALAGYLGGHVDERRKQPREDLLTKLVEAELDGERLSRSDVVNFANILLLAGHITTTMLLGNAVLCLDTHREWDERVRADRSLVPPMIEESLRYLTPFAAVARTTVREADIGGVTVPADQVLLLWVAAANRDERVFRDPDTFDPLRAENPHLAFGRGIHFCIGAPLARLEGRVALDILFDRYPTLRTIPGEPPKFQVNPNMTGVRELPLTTK
>NC_017186.1|WP_013224574.1|2893282_2894011_-|metallophosphoesterase-family-protein
MNVAVLADIHGVLPALEAVLAEPDVRAAEKIVLLGDLLAGPMPLETLERLQALGDRAVWVRGNADRELAESARTGGSFVPDPIFPWAAKQLRPADLPVLDALPLTVAVDGVLFCHATPRDDTEIVLVDSSPERWAEVLDGVSASTVVCGHTHMPFVRLADRRLVVNPGSVGMPYGARGAHWALLCDGVELRCTEYDVEAACRFLAEHCAYPDIEAWADFFVRNPASDTEALRVFSGRGTSST
>NC_017186.1|WP_013224573.1|2892444_2893311_+|SGNH/GDSL-hydrolase-family-protein
MVVDVTVMSVDVTPLPEPSRPPLAAVPPLAAVPPLNRARRLVVLGDSTAVGLGDPLPRRAGWRGVGPLVAAALGVDDSGYLNPSFAGARMRCVLTEQVPAAVAHRPDVALLVAGMNDTLRPDFDAARIADDLTEVIRRLRDTGTTVLPVRFHDHSKVFRLPPSLKRALSARVAELNAAIDEVVAREGVSCLDLGRLPGAYDLASWSVDRLHPSELGHRMLANGFTGLLADAGFAVPEPVSLTCSGGAEPSATGHVGWLVLKGIPWLWRRGREFLPYAAAIMWNSFRAR
>NC_017186.1|WP_013224572.1|2890882_2892064_+|hypothetical-protein
MTVDTSSAGDAGVGAGAEQLAIAAAVAAGESVLSRRFGSAITLVAPEDLAGSGPATVVRARVVSSFALPRTLVIKHYRDRPETGADPFAQEAVSYQLFTALAPDERMCPELVAHDGRDRVLVLEDLGRTPTLEDKLYARDSRAAERALLSWARSLGRLHASTAGREADFNALLRRLGGPAKGDSDGVDELCGRVPSLIRKRLGIPVPDEVLAQVTAALDQSRAAGFRAFSPVELSPDNNLVTGQGVRFLDFENGRVRSALVDAAQLRLPFASWPDALALPAGMSEAMIAAWRAEVVGVWPAFADDEVLAAHLTSSELLRVWLITGEELGALNLSRHAAPVSREAAFVTWWRDLAKHAGYVRMGAVSEFAARVAAALAARLGPHADLAFYPAFR
>NC_017186.1|WP_014466857.1|2889855_2890803_+|DUF389-domain-containing-protein
MLHLRAVCPPDKTAEALDILRAHAGTAHLIVHRGAAVEPAGDLVEADIAREAADEIVDALCKLELDHTGGITLEALDTALSDAADKAEEAAPGEAADAVVWQELLGRTGEESRLNVTFLAFLVIACLLAAVGVLTDSSVTIVGAMVVGPEFGPLAALAVGLVLRHRQLIRQAGAALAVGFPLAMVVTLGGTLLVRATDVFGEKAFQLQQHNEVDFVFSVGAPSLVVAMLAGAAGMLAMTSAKSAALVGVFISVTTVPAAGYAVVAAVAGEWSRCLQSVGQLLVNLLGIVAAAAIVLIVRRNGQRSPVGMRPLSRG
>NC_017186.1|WP_013224570.1|2888080_2889856_+|aspartate--tRNA-ligase
MLRTHNAGTLRAGQAGQTVTLTGWVARRRDHGGVIFIDLRDASGVAQVVFREGEMAERAHALRSEFCVKIVGEVAKRPEGNANAEIPTGEIEVLATQLEVLSEAAPLPFPIDDRVDVGEEIRLKHRYLDLRRSGPAAAMRLRSEVSRAAREVLHAQDFVEIETPTMTRSTPEGARDFLVPARLKPGSWYALPQSPQLFKQLLMVGGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVEQDDVIALGEDIVSALWKLIGHEIPRPIPRITYHEAMAKYGSDKPDLRFDLEITDMTEFFADTPFRVFQAPYVGAVVMAGGADQPRRQLDAWQEWAKQRGARGLAYILVNVDGTLGGPVAKNLSETERENVAAAAGAKPGDCIFFAAGKAASTQPLLGAARDEIGKRLGLIDENAWSFVWVVDAPLFAPVEDIGDDVAVGSGKWTAVHHAFTSPTPEWIDKFEQDPGNALAYAYDIVCNGNEIGGGSIRIHRGDVQKRVFSLMGLGEEEAQEKFGFLLDAFAFGPPPHGGIAFGWDRIVMLLAKADSLRDVIAFPKTGGGYDPLTAAPAPITAQQRKEAGIDAKPAAAPQN
>NC_017186.1|WP_013224580.1|2899417_2899804_+|DUF948-domain-containing-protein
MSAGQIAALIAAGAFVVLVVLLAIPLIKLGKTLDAATEAIERTNSNTDPLLIGANETITHVNTQLERVDGITANAQAVTGNVSALASVFTATLGGPLVKTAALSYGLSKAIKARKKKSALKAARKAGK
>NC_017186.1|WP_013224581.1|2899800_2900106_+|hypothetical-protein
MKRLFWLGVGVVTGVVLSRKAAETARQATPAGLASNLGDAVRELAGAVGSFGAEVRAGMSEREQELHDMVEERTGVTAPRAEGRHAAAARRPVRRARRAEG
>NC_017186.1|WP_013224582.1|2900178_2902839_+|alanine--tRNA-ligase
MDTHEITDRFLRHFEGRGHTRVPSAPLILDDPNLLFVNAGMVQFKPYFLGEAPPPYPRATSVQKCVRTPDIDEVGKTTRHNTFFQMAGNFSFGDYFKEGAIEAAWELITKPQTEGGFGLDPERIWATVYNDDSEAAGLWRKLTGLPGERIQARDGKDNYWDMGVPGPGGPCSEIYYDRGPAYGREGGPVADEDRYIEIWNLVFMQDVRGDLSPKLGHKPIGELPKKNIDTGMGVERVATILQGVENVYETDLVRPVIGRAEEFSGRRYGSNHADDVRFRVIADHARTGVMLIGDGVTPGNDGRGYVLRRLLRRIVRSTRLLGVQEPVLQEFAKVVRDTMGPTYPELVSGFDRINEVVRIEEEAFLSTLTSGSRIFDMAAEETKRGGGDVLAGDKAFQLHDTYGFPIDLTLEMAAEQGLTVDEEGFRTLMNEQRTRAKADAAARKTGHGDLSEYRKVLEQHGETEFLGYTDLQAEAKVVALLEDGQPVRSVSAGKKAELVLDRTPFYAESGGQVADTGVLLGDGVELKVLDVQKIVPGLYVHRVEVVDGEIGLDSKVTGSVDAHRRLSIERSHSATHLVHAAVRGAYGKRAAQAGSLNSPGRMRFDFTTPGSVSADVLTEVEQEVNDYLQTNVEVQSFTTTKDKALELGAVALFGEKYGNDVRVVDMGDYSRELCGGTHVDRIGQLGLVKLVSDASIGSGVHRVEALVGTDALKYVRKEQLLVSQLANTFKVPSDQLPGRIDDVLTRLKNAEKEIAQLKTQQVLGSAGALVDKAQEIGGVTVVAEVVPDVDGNGLRALASDIRGRLGTRPGVVALFSPAGEKLSFVVATTKAAQEKGIAAGKLVPSFAEKIGGRGGGKPDMAQGGGTNPAGAAEAVTALRSAIAGVG
>NC_017186.1|WP_034284342.1|2902831_2903332_+|Holliday-junction-resolvase-RuvX
MVNRGNRGPDRPGNDDPGRGRRLGVDVGSVRVGVALSDPAPVLASPLVTLSRDATDDTDLDQLAALVTEHEVVEVIVGLPRTLANRQGPAAELAIAYSERLAGRIAPVPVRLGDERLTTVTASRILSQRGVKGRKQRAVVDQAAAVEILQAWIDAAAAHRAREGDR
>NC_017186.1|WP_013224584.1|2903328_2905608_+|endolytic-transglycosylase-MltG
MNEQPPEPPRGRRRLREPEAATPPPSRPAPRRGDPRAAEARRTPSGEHELPRRGQASSGEYDLPQPSRRARREEPPGYDPRRGAPQPGRRRLEPPATLSPADADLGPQERRAAPARAAHARHGLDEGSEIEPPASRRRRAAPEPDEGTEIEPPASRRRRAAPEPAEGTEIEPPASRRRRAAPEPDEGSEIERPAPRRRRAAPEPDAAEDPPPRRRALPERIEPAPPRRRRAAPDAAEPQPGRRAPAPEPAEAAGPPVRRRAAPDAAESVDARRRRAAPDPDADPRREAPEPPARRLAQPGDRTVGVPEPGAEPRRRPAAPPAREEPVTDVLPALAPLPPAEPPRTSPEEPGLVAEDDEYADYDEYDDYEDYDEPEYDEEYEEPRKPRKKGKRALGWIAAIAVIALLAGGAWYGFNKFFGYDDFDGAGNEDVVFQVDDGDTTSAIGVKLTTAGIVASSKAFVKAGEGNPKLARVQHGFYVMKSHMSGASAVERLTTPASRVGQLEIRPYTQFDDITQPDGKVTPGVYSLMAKASCAQLNGKSTCVSADDLRKTVDGADLKQLGVPDWAIEPANKADRKDRRLEGLIAPGVYDVKPGSSAQDILGQLVHSSAEAIQNAGLTPQSAGPGVTPYQTLIIASIIEREAVKADFGKLSRVIYNRLAQNMRLQMDSTVNYVLDRPTLLTDEADRAKSGAYNTYRNTGLPPTPIAVASSDAIKAAVKPPDGEWLYFVKCEKNGLSCFAVSNDEHNRNRDLAKARGVI
>NC_017186.1|WP_071831604.1|2905597_2906452_+|shikimate-dehydrogenase
MSSEARKAAVLGKPVAHSLSPVLHGAAFAALGLTGWTYERIETSAEELPGLVGRLGPEWAGFSVTMPGKRAALDHADEVTPRAAAVGAANTLVRTERGWLADCTDVEGVTGALRAAGGYEPSPADTAVVLGGGGTAAAAVVGLAALGVRQVRLVVRDPARAGETLDAAKRAALDVDVLRWAETDFAALGSAAVLVNTVPPDAVAAHVAELAAVEHVLDVIYHPWPTPLAEAVAARGGRLATGLDMLLHQAFGQAEHFTGRPAPRAAMRDALRAATGDLLPLPID
>NC_017186.1|WP_013224586.1|2906515_2907796_+|GrpB-family-protein
MTSQDASSDEEVQGAWVGEAPKLNSTVTLADYDPEWPKLFEREAERIRGALGERVLVLEHVGSTSVPGLCAKPIVDILLEVPDSDEEAAYVPALEAAGYRLVIREPDWEKHRCFKGPDTNINLHVYSPGNGQTPRYRLFRDRLRSHPEERELYAAKKRELAAKTWTYIQNYADAKTEVVEEILGRARAAQYDGHSEAYAEHAEKSVTNAFYDRPAILDLAGDVDGLSVLDAGCAAGHLSALLAGRGAEVLGVDSSAGMIAVARRKFGDVARFEVADIAGPLAVPDGSIDVVTASLVLHYLADWGQALAEFRRVLKPGGVLVFSVHHPGEDWRWFGKENYFELELLEDEFPPGTVVRFHRRPLSWTFQAVRDAGFAVDRLVEPMPVADAEAADPEWTANLRTKPRFLYFRAVSPAWRAPGSGRRSPG
>NC_017186.1|WP_013224587.1|2907746_2908406_-|TetR-family-transcriptional-regulator
MAKSEETRSLIVTTAMRLFTENGYDRTTMRAIAAEAGVSVGNAYYYFSSKEQLIQGFYDEMARQHLTAARRLLTGETGFAARLKAVLLCWLDVAEPYHRFGTQFFVNAADPESPLSPFSDDSSAAREASIGLMREVVEGSDVKLDPELRDRLPELLWLYQMGVVLFWVHDRSAGTKRSRLLVERSVPLLARLAALSRLRVFRPVSREIVDLIQELAKRD
>NC_017186.1|WP_013224588.1|2908431_2908848_-|hypothetical-protein
MDLIVVAYALYLLLSIPLTVLVARTLSKHGRTFLTEVFADSPGLANAVNQLLVVGFYLVSLGFVALFLTSSTLVLTTRGVFELLSVKIGTVALVLGVMHLLNVLVFNGIRRRHLAPPAPAPVPLPYPGMPQAPPFPAP
>NC_017186.1|WP_013224589.1|2908947_2910213_-|alpha/beta-hydrolase
MTMAGTDPAAVATAVVDMAATGRYAEVEGLFAPRLRAAASADTLRVGWETEIAKIGPVRAVGDPVSEPAGAGLVRVSVPVTGAHGGLTVVMSVDDAGLLHGLRLAPPSGTTWAPPAYAEPDRFTEHEVTVGAGPLAVPGTITRPRRRGPWPGLVLLASGPADRDLTTGPNKPFKDLAWGLASRGIAVARFDKVTHVHPETGSAAGFTMADEYVPHAVAAVHLLQQQRKVDPVRVFVLGLSGGGKAAPRVAAAEPSVAGLISLAGDTLPLSRAAVRVARHLAELNPGPAAAAAVESVARQAALVEDPGLSPATPAADLLFGWPASYWLDLRGYDPVATAAGLGRPILILQGGRDYQVTAAGDLARWREGLARRPDVTIRVHDADDHLFFRGEGPSTPAGYESPQHVDPAVVTDIADWISTPR

Crispr_ID: NC_017186_11

• CRISPR_ID: NC_017186_11
• CRISPR_location: 3229412-3229519
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_11

Consensus_repeat	Method
GCCGATCCCCGTCCCGCCGGGCGTCG	CRISPRCasFinder

spacers of NC_017186_11

>11.1|3229438|56|NC_017186|CRISPRCasFinder
CCAGGCGGGATCTCGGCAGCCTGGTGGCTGGGCGCCCGCAGGTGTATCTCAGCGCA

CRISPR arrays and Neighbor proteins around NC_017186_11

CRISPR arrays

The CRISPR arrays of NC_017186_11

>merge|NC_017186|11|3229412-3229519|CRISPRCasFinder
GCCGATCCCCGTCCCGCCGGGCGTCGCCAGGCGGGATCTCGGCAGCCTGGTGGCTGGGCGCCCGCAGGTGTATCTCAGCGCAGCCGATCCCCGTCCCGTCGGGCGTCG

>NC_017186|11|10|3229412-3229519|CRISPRCasFinder
GCCGATCCCCGTCCCGCCGGGCGTCG	CCAGGCGGGATCTCGGCAGCCTGGTGGCTGGGCGCCCGCAGGTGTATCTCAGCGCA
GCCGATCCCCGTCCCGTCGGGCGTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013224882.1|3224691_3225078_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013224879.1|3221478_3222168_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_017186.1|WP_013224893.1|3234761_3235583_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|130314
NC_017186.1|WP_013224888.1|3230409_3230844_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|236092
NC_017186.1|WP_013224889.1|3231015_3231306_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013224884.1|3226784_3227459_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NC_017186.1|WP_013224885.1|3227498_3228344_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NC_017186.1|WP_049878122.1|3232610_3234725_-|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NC_017186.1|WP_013224883.1|3225125_3226757_-|acetolactate-synthase-I/II/III-large-subunit	unknown	unknown	gnl|CDD|181337
NC_017186.1|WP_014466909.1|3229672_3230284_-|phosphate-uptake-regulator-PhoU	unknown	unknown	gnl|CDD|223776
NC_017186.1|WP_013224881.1|3223316_3224705_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|223154
NC_017186.1|WP_013224898.1|3237262_3238252_+|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176237
NC_017186.1|WP_013224897.1|3236856_3237180_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|378968
NC_017186.1|WP_013224877.1|3219590_3220079_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013224880.1|3222284_3223202_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239490
NC_017186.1|WP_013224878.1|3220072_3221482_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_017186.1|WP_013224886.1|3228317_3229322_-|pirin-family-protein	unknown	unknown	gnl|CDD|224655
NC_017186.1|WP_013224890.1|3231623_3232016_-|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl|CDD|379915
NC_017186.1|WP_013224891.1|3232183_3232609_+|nitroreductase-family-deazaflavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|281995
NC_017186.1|WP_013224896.1|3236344_3236785_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013224879.1|3221478_3222168_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.22213e-84
NC_017186.1|WP_013224893.1|3234761_3235583_-|ABC-transporter-permease	gnl|CDD|130314	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein. This model describes daunorubicin resistance ABC transporter, membrane associated protein in bacteria and archaea. The protein associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	7.43091e-33
NC_017186.1|WP_013224888.1|3230409_3230844_+|single-stranded-DNA-binding-protein	gnl|CDD|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	3.46432e-80
NC_017186.1|WP_013224897.1|3236856_3237180_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	1.19118e-05
NC_017186.1|WP_013224884.1|3226784_3227459_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.62219e-37
NC_017186.1|WP_013224885.1|3227498_3228344_+|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	3.09023e-25
NC_017186.1|WP_049878122.1|3232610_3234725_-|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	6.28025e-116
NC_017186.1|WP_013224883.1|3225125_3226757_-|acetolactate-synthase-I/II/III-large-subunit	gnl|CDD|181337	PRK08266, PRK08266, hypothetical protein; Provisional.	0
NC_017186.1|WP_013224881.1|3223316_3224705_+|aspartate-aminotransferase-family-protein	gnl|CDD|223154	COG0076, GadB, Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism].	1.3656e-72
NC_017186.1|WP_013224898.1|3237262_3238252_+|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176237	cd08276, MDR7, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.68849e-150
NC_017186.1|WP_014466909.1|3229672_3230284_-|phosphate-uptake-regulator-PhoU	gnl|CDD|223776	COG0704, PhoU, Phosphate uptake regulator [Inorganic ion transport and metabolism].	3.31119e-10
NC_017186.1|WP_013224880.1|3222284_3223202_+|phosphatase-PAP2-family-protein	gnl|CDD|239490	cd03396, PAP2_like_6, PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	4.44459e-09
NC_017186.1|WP_013224878.1|3220072_3221482_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.19608e-49
NC_017186.1|WP_013224886.1|3228317_3229322_-|pirin-family-protein	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	5.62397e-62
NC_017186.1|WP_013224890.1|3231623_3232016_-|zinc-ribbon-domain-containing-protein	gnl|CDD|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	5.26815e-06
NC_017186.1|WP_013224891.1|3232183_3232609_+|nitroreductase-family-deazaflavin-dependent-oxidoreductase	gnl|CDD|281995	pfam04075, F420H2_quin_red, F420H(2)-dependent quinone reductase. This family of proteins is found in the genera Mycobacterium and Streptomyces. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. Rv1558 is an F420H(2)-dependent quinone reductase involved in oxidative stress protection.	2.55897e-29
NC_017186.1|WP_013224896.1|3236344_3236785_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.76215e-11

Protein sequences

>NC_017186.1|WP_013224886.1|3228317_3229322_-|pirin-family-protein
MSNTEAAPAELACGDRPAAADPDRPLVEVLAPRAVPLGGPRAMRVRRTLPQRSRSLIGAWCFADHYGPDAVSGPGAMDVAPHPHTGLQTVSWLFSGEIEHRDSLGTHALVRPGELNLMTGGHGICHSEVSTAATKTLHGVQLWVALPERHRHTARAFDHYVPSVNRIEGAEIRVFLGSLAGRTSPIPTFTPLLGAEVVLGPDAHMSLGVDPGFEHGVLADTGDVVVAGTRVRATELGYVGTGVRSLTLSNRGTEPARFLLLGGTPFDEEILMWWNFVGRTHEEIAAFREAWEAGSDQFGSVTGYAGERLPAPALPAVRIKPRRNPGSGQETAHG
>NC_017186.1|WP_013224885.1|3227498_3228344_+|alpha/beta-hydrolase
MPIFSAPDGTALAVHLWGSGAGPPVVCLPGGPMRAGGYLGDLGGLSTRRRLAVLDLRGTGDSEEPADPATYRCDRQVEDVEALRKHLGLERFDLLGHSAGASLAVRYAARYPRRLSRLALIAPSPRAVGFDVSPGERRRIMARRSGAPWFAAAAAAYESIAAKKATSADWAAFAPLYYGRWDAAARQHQAGEPGQRNGVAARIYNSAGAFEPETTRAALGAVTAPVLVLAGELDWIAGPAVADRFAALFPDGRAVVLPGAVHYPWLDDAPAFRSAVGGFLA
>NC_017186.1|WP_013224884.1|3226784_3227459_+|GntR-family-transcriptional-regulator
MVSYMIGASAERPVTKSQLAYETIKARILAGRYGPGYRLVLDQIGRELDVSAVPVREALRRLEAEELIEFERNVGARVVATDPVAYQHAMQTVAIVEGAATGLAAPLLTAETLGRARELNDRMRRSLAEFDPVAFTALNAEFHEVLFGACPNPNLVDLVQRCWTRLAAVRDSTFTSVPGRAPESVVEHERLLALIEGGGEPEEVERFARGHRMATLEAYLARER
>NC_017186.1|WP_013224883.1|3225125_3226757_-|acetolactate-synthase-I/II/III-large-subunit
MPMSPVIPTAADLIVGGLRAHGVDTVFGLPGVQTYDLFDSLARTGGDIRVIGARHEQTVAYMAFGYAQATGRTGVCTVVPGPGVLNASAALLSAYGASAPVVCLTSEIPRAFLGRGLGHLHEMPDQLATLRSITKWSALVEHPVQVPDALATAFREAAGGRPRPVSLAVPWDVLGLRAPAAVTGPLPLPRPAVDPVATEKATELLQSAKHPMIMVGGGARHAAAEVRALAERLQAPVVPFRGGRGIVGDDHPLGFTCVSGFERWPETDVVIGIGSRLELSWFRWPGKPAGLKTILLDIDPRQATRLEADVAIVADAADSTAALTAAVGPQRTDRTAEFTALKAAVAERVTDVGPELEYLRAIRDVLPRDGFFVEEICQVGFASYFGFEVYAPRTFVTCGHQGTLGFGYPTALGVQAAFPGRPVVSVAGDGGFMFAAQELATAVQYGLSVVAVVFDNGYYGNVHLDQERLFEGRALGGRLGNPDFARLAETFGALGLTARTPDDLRDALDKAFAAGRPALVHVPCELGVGTSPWKYLMPESDRS
>NC_017186.1|WP_013224882.1|3224691_3225078_-|hypothetical-protein
MEVLAPQWVLTASHCAGRNPTGARAGVPKGRQQDAAIRYASGPGCAPWHGTSGAALLGPDGTTVAGIHNTHNDSGEQCSADNPCEVDSAGAVTSVPGRGYGQQVAGIAACLKGSEVDLTRPGCPLTGA
>NC_017186.1|WP_013224881.1|3223316_3224705_+|aspartate-aminotransferase-family-protein
MDPRLADDLHALPDLLDAASKLAAEALAGLDRRAAAVPPVALEPLPLPADGAGARGALDEFARRWEPGFAASAGPRYLGFVTGGATPASLAGDWLTAAYDQNPASGMDSSAQDLERETVGWLAELFGLDPEFSGAFVTGATMSTVTGLAIAREWLGERAGVAVSEAGAAALGPVTVLSGSPHSSVLKALSFLGMGRSALRKVPVLPGREAVDVAKLAEALETLDGPAVVVANAGTVNTVDFDDLRAIAALKQRYGFWLHVDAAFGGFAALVPEHAALTAGLDQADSVVVDLHKWLNVPYDSAVQFTRRRDLQLRVFSNNAAYLGEIGETPDFLHLTPENSRRLRALPAWFSLVAYGRAGHREIVERCVALARDLGARIDGSPHWHLLAPVRLNVVCFTPAGEVTQDRIDTLVRDIAEDGTTFLTPTVYDGRPALRAAFSNWRTTGADVDRIFAVLERLVRLP
>NC_017186.1|WP_013224880.1|3222284_3223202_+|phosphatase-PAP2-family-protein
MILTDAPSATRPARPAPVPRAASRTAVLAASAAGFALAFVAAYLLFVRTEAGRGVENGVVRSAQSAGTTVDWAAPLREADLVVVLGGVAVLIVAISVVRRRLALGVMTLVLLAAPLVVAQLLKLYVLDRPGTGDRLGVAGHNSFPSGHASAAMAVLVALAIVLPRRFRRAALVTGGFGVAWVSAAAVALGWHRLSDTVGGGLLVAAVTCAGAAVVSARRPDGDRVPLVPVLTGFLAPPALVPAGYAVLATATSGAAQFVAALVLAALSSMAVVLLLAGPLRRVAFDPAESRVRRLRRHPVPRTHP
>NC_017186.1|WP_013224879.1|3221478_3222168_-|response-regulator-transcription-factor
MAEVLVVEDDAAVREGLQLALRRQGHVVHTAESGELGIEVLVRHRPDLVVLDLMLPGMDGFETCRRMRAAGPVPIIMLTARTDDFDIVAGLEAGADDYVAKPVEPRVLDARIRAVLRRAAVERPDGPAAAEERHGDLVIDRAALEVTKRGEPVSLTPTELKLLLELSRTPGQVYSRQQILSAVWDHDYLGDSRLVDACVQRLRAKIEDVPAKPEHVQTVRGFGYRFGRS
>NC_017186.1|WP_013224878.1|3220072_3221482_-|HAMP-domain-containing-histidine-kinase
MTAPRVRSWLAGLRPRLVAAFAVIMILGVTTAVGVSYVFARRAILEGVQDQTMLKLRDQIVAYLPTVSLPPSQATLDAFAATLKSSNALVVYGNLHATSGLSIDDVPGDLRHAVATTTNIQFQRVDVQGFPLFFVGVPVQTGGGKPSGLEVYAMTRLIDQQEAIDELARNAWLYSALALPLAVGVALLAARQVLRPVRALNTAASQLGRGRLDVRLPAKGSDELAQLVTTFNHTAAELERTVGTLRAMEADARRFVADVSHELRTPLAAMNAVTDVLDEDAEQLPPDTAVAARLVSAETRRLTRLVQDLIEISRFDAGRAELRREELDVAAAVTDSLAARGWEAGADLVTDLPAGITARLDRRRLDIVVANLVGNALRHGAPRVEVVLRKELGDVVLTVTDHGPGIPAEALPKVFDRFTKADSARARSGGSGLGLSIARENARLHGGDIVAANTGTGARFELRLPGEAW
>NC_017186.1|WP_013224877.1|3219590_3220079_-|hypothetical-protein
MVKKLVVLAVLLLVSACGVKPTPVVAAGPAPTLRVPATDGRGTDLILYFVLDDRVAPVARSSDGVAGVEAALSMLLAGPSTDERADGYTTALPRPSGAITVTPGSPATIGVPFPLRPLTGAGINQLVCTAFAALAAQGGYATGGTVALAGPDVLLPYQTCQA
>NC_017186.1|WP_014466909.1|3229672_3230284_-|phosphate-uptake-regulator-PhoU
MPTAFQQELVTLAHRLADLCDLVASTLEEATRSVLESDHTLGGRAREQAAAVTSLGAACEDQACALLALHAPREAEVKAVVAAVHTAADLTRMGGLAREVAEARESVPPEVRPALGRLGDHAAATARALREVLVGGDGTGLGDAAALVGAAEREVREWADGREGLRGAGFAVELALLAAVYGRFAATAVRIGRRAAGFAPVGA
>NC_017186.1|WP_013224888.1|3230409_3230844_+|single-stranded-DNA-binding-protein
MAGETTVTVVGNLTSDPDLRFTPAGSAVANFTVASTPRVFDRESGAWRDGDALFLRCSLWREYAENVAESLVRGARVVVHGRLRQRSYDTKEGEKRTVVELEVEEIGPSLRYATAKVTKVSRATGGEGSSAWTPEPVGAVKPPF
>NC_017186.1|WP_013224889.1|3231015_3231306_+|hypothetical-protein
MNGNEKTGSPAAHPVVNHRMRAMLRAVGAGRGRVSCSSEPDLFIDGLSCGDQFAAHALAHQGLVRAARPGRPGELVPAVLTPAGQALVNPEQRSVA
>NC_017186.1|WP_013224890.1|3231623_3232016_-|zinc-ribbon-domain-containing-protein
MLIWGWRTRIYVLAMTTFLCGRCGNPAAHAVRKAVTKFTLFFIPLFPISVKYTAQCTFCGIENRIPKEDALRLQAQEEQGQARQQAAPGYPPHPSQGAAPQAGFPQQGYPQHPSQPQGFPQPGQFPQQGQ
>NC_017186.1|WP_013224891.1|3232183_3232609_+|nitroreductase-family-deazaflavin-dependent-oxidoreductase
MPSDFALKTMNAVHRGLIKLTGGRVGWQVAMPVLELTTVGRKSGQPRSVLLTSPHQEGDAVVVVASRGGDDTHPAWFLNLRDHPDVEVSLKGGPKKPMRARVADAEERARLWPKITADFKNYAQYQTKTEREIPLVFLEPR
>NC_017186.1|WP_049878122.1|3232610_3234725_-|penicillin-binding-protein
MPNVEFVKRRGGVVPFAGLCVLAGILVAGTVAPAAIGAGLLSNQVSDSVDAISARLAAADLPLTTTVTDRDGTPIATLYAQYRLPVTAAGIATTMKAAIIAIEDRRFYTEGGVDLQGMLRAAVNDSAGGSLQGASTITQQEVKNYLINVVDRNDPAAQQADREDSLARKLREAKMAVQLNDTMSKDDILANYLNVVEFSGTVYGVGAAAQAYFGTTADKLTVAQAALLAGMVNNPSVYNPYTHPDKALQRRNLVIDDMVTNGSIPASYAATAKAAPLGLLPNGPVTPSGTCLGAAPDAGFFCAYAESYLVHAGFTADRLATGGYTIKTTLDPRVSQVSKDAVDANVPTTQDGVANTFAVVQPGQGGHQVLAMVANRNYGTDPARGETSTDIVADASNEFGAGSSFKIFTSAAALVTGQAGLDTPLPNPDSQCFPVPDAHSSCYTVHNDGHYADPITLADGLATSPNVAFVGLESQVGMPAVLDMAAKLGLRNTLATNDAGRTPDPKSGNPQYSEPQSQYFRNLLSFTLGNSPVSPLEMANVSATLMSGGVWCPPNPILSVTDRNGNAVPVAQQACERVIPEGVADTLEAGLSKDTTSGTSAEAARAAGWTRPDIGKTGTTQQSESVAFVGGVDGYAVSSMVFADGPHPREICPGTPVHLGDCGHGAFGGTVAAPPYFHAMSRLLAGVPDQPIPAADPAYLAARS
>NC_017186.1|WP_013224893.1|3234761_3235583_-|ABC-transporter-permease
MSVPLAVPPAASADPGPLRRLRVLGARVGAMCLVELQKLRRDQTELLTRAIQPALWLLIFGETFTRLRAIPTGSTPYLDFLAPGILAQSALFIAIFYGIQIIWERDAGVLAKLLVTPTPRAALVAGKAFAAGVRALVQALMVLILAAVLGVGLTANPLKLLAMAVVLVLGSAFFCCLSIVIAGIVRSRERLMGIGQAITMPLFFGSNALYPVDLMPPWLKALSHVNPLSYQVDALRGLLIGTPAHLGTDFAVLAVATAVAVAVASALLGRLAR
>NC_017186.1|WP_013224896.1|3236344_3236785_-|MarR-family-transcriptional-regulator
MTELADRLLGAVQGIRRVVRRRVRADVPGMPLPGAQVELLRVVADHPGIGVAAAARELHLANNSVSTLVNQLADAGLLRREADPADRRAARLEVTAAAADRMAAWRRARTGLVADALAELSEEDIAAIEQALPALEKLTGILKEQP
>NC_017186.1|WP_013224897.1|3236856_3237180_-|helix-turn-helix-transcriptional-regulator
MASRTATPLDHPALEDVSFSAALEALRDPHRLTMVAALAREPGQSCGAIMPPVSKPAASRHFKILRAAGLLRQWDSGTQRLNALRREEFDVRFPGLLDLALAEAARG
>NC_017186.1|WP_013224898.1|3237262_3238252_+|NAD(P)-dependent-alcohol-dehydrogenase
MRVYRPRSGRLVQREEPMPEPRRGEVLVRVRAVSLNYRDLLILNGDHIATGATDLIPVSDAAGEVVAAGEGVTRFAGGERVLNAFHPDWIAGRMPETMVGYGNGRDGWLAEYRAVPEHALVALPDSLTFEQGATLPCAAVTAWTSLEGVRPGDVVLTLGTGGVSLFAVQLAKARGARVVATTSSAAKAAKLTGLGADTVIDYVATPEWGKAVLDATGGRGADRIVEVGGPGTFAQSLVAAGTHHAEIALVGFVGRSGPPVDFMDLFRSGATVRKIWVGSREDTEDLLRWLDVWPLEPVVDSVHSFEEAEAAFRRFESRENFGKVVIATA

Crispr_ID: NC_017186_13

• CRISPR_ID: NC_017186_13
• CRISPR_location: 3580882-3580967
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_13

Consensus_repeat	Method
CCGGCTTGGGGCGAAGCCCCGGA	CRISPRCasFinder

spacers of NC_017186_13

>13.1|3580905|40|NC_017186|CRISPRCasFinder
TGTCACGGCTTCTTTGCGGGGGCTCCGGGCGGTGGAGCCC

CRISPR arrays and Neighbor proteins around NC_017186_13

CRISPR arrays

The CRISPR arrays of NC_017186_13

>merge|NC_017186|13|3580882-3580967|CRISPRCasFinder
CCGGCTTGGGGCGAAGCCCCGGATGTCACGGCTTCTTTGCGGGGGCTCCGGGCGGTGGAGCCCCCGGCCTGGGGCGAAGCCCCGGA

>NC_017186|13|12|3580882-3580967|CRISPRCasFinder
CCGGCTTGGGGCGAAGCCCCGGA	TGTCACGGCTTCTTTGCGGGGGCTCCGGGCGGTGGAGCCC
CCGGCCTGGGGCGAAGCCCCGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013225182.1|3588212_3588935_-|ArsR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|319973
NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270450
NC_017186.1|WP_176742152.1|3567387_3568386_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235935
NC_017186.1|WP_013225180.1|3586884_3587832_-|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|107205
NC_017186.1|WP_013225174.1|3580121_3580820_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NC_017186.1|WP_013225168.1|3571241_3572489_-|low-temperature-requirement-protein-A	unknown	unknown	gnl|CDD|377704
NC_017186.1|WP_013225172.1|3576525_3577290_+|MHYT-domain-containing-signal-sensor	unknown	unknown	gnl|CDD|225837
NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase	unknown	unknown	gnl|CDD|185683
NC_017186.1|WP_013225166.1|3568741_3570535_-|thiamine-pyrophosphate-requiring-protein	unknown	unknown	gnl|CDD|181344
NC_017186.1|WP_013225175.1|3580978_3582469_-|family-20-glycosylhydrolase	unknown	unknown	gnl|CDD|119333
NC_017186.1|WP_013225167.1|3570660_3571137_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_017186.1|WP_013225183.1|3589013_3590168_+|isovaleryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NC_017186.1|WP_013225164.1|3566648_3567086_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013225171.1|3576131_3576512_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NC_017186.1|WP_013225170.1|3575649_3576135_+|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|224929
NC_017186.1|WP_013225173.1|3577331_3579728_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013225176.1|3582468_3583287_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_017186.1|WP_013225184.1|3590543_3592838_-|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226418
NC_017186.1|WP_013225181.1|3587841_3588216_-|VOC-family-protein	unknown	unknown	gnl|CDD|319924

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013225182.1|3588212_3588935_-|ArsR-family-transcriptional-regulator	gnl|CDD|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	1.75055e-53
NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.3641e-98
NC_017186.1|WP_176742152.1|3567387_3568386_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|235935	PRK07109, PRK07109, short chain dehydrogenase; Provisional.	2.63382e-174
NC_017186.1|WP_013225180.1|3586884_3587832_-|pyridoxal-phosphate-dependent-enzyme	gnl|CDD|107205	cd01562, Thr-dehyd, Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.	9.12836e-78
NC_017186.1|WP_013225183.1|3589013_3590168_+|isovaleryl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	3.39986e-129
NC_017186.1|WP_013225168.1|3571241_3572489_-|low-temperature-requirement-protein-A	gnl|CDD|377704	pfam06772, LtrA, Bacterial low temperature requirement A protein (LtrA). This family consists of several bacteria specific low temperature requirement A (LtrA) protein sequences which have been found to be essential for growth at low temperatures in Listeria monocytogenes.	3.52367e-56
NC_017186.1|WP_013225172.1|3576525_3577290_+|MHYT-domain-containing-signal-sensor	gnl|CDD|225837	COG3300, COG3300, MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms].	1.47748e-32
NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase	gnl|CDD|185683	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16. The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.	3.03408e-15
NC_017186.1|WP_013225166.1|3568741_3570535_-|thiamine-pyrophosphate-requiring-protein	gnl|CDD|181344	PRK08273, PRK08273, thiamine pyrophosphate protein; Provisional.	0
NC_017186.1|WP_013225176.1|3582468_3583287_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.85483e-80
NC_017186.1|WP_013225167.1|3570660_3571137_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.96098e-11
NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.76092e-71
NC_017186.1|WP_013225174.1|3580121_3580820_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.24644e-56
NC_017186.1|WP_013225170.1|3575649_3576135_+|roadblock/LC7-domain-containing-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	1.27529e-21
NC_017186.1|WP_013225171.1|3576131_3576512_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	2.02345e-25
NC_017186.1|WP_013225175.1|3580978_3582469_-|family-20-glycosylhydrolase	gnl|CDD|119333	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	5.01817e-169
NC_017186.1|WP_013225184.1|3590543_3592838_-|LuxR-family-transcriptional-regulator	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	3.53174e-56
NC_017186.1|WP_013225181.1|3587841_3588216_-|VOC-family-protein	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.37358e-14

Protein sequences

>NC_017186.1|WP_013225174.1|3580121_3580820_-|GntR-family-transcriptional-regulator
MKRDRVRRHLLKVIENAGPGTGLASERDLAAELGVSRPTVRAAIDELTRTGLLVRQRGRGTFTSPHKVTQELATGLAVPPAEGHWTSRVVAFAVSPAPRTLAGELELEPGAPVLRVTRVRYVDDEPIAIESLALPAALVPGLRPADLEAGNFYRLLRERFGIAVQDAVQTIEPAVTDPGQAELLEIAVYAPILHIERLTRDTTGRIVELTRSSYRGDRYRITSKLRFDAESG
>NC_017186.1|WP_013225173.1|3577331_3579728_-|hypothetical-protein
MRRRILGAVLPLVLTTAVAVPLPAAADPAPAVSALTKSVQRTGSPAAHGATANWVVGYEDHATTTGAAAITDAVGAGQAYQSGSLHVPPGWTPEWSTDGSTFAGAEPASGVTAVRATNPAAGPDATQLTGALTPPVQAVTTATGGDGFSPILYRTPGGSLQAWNIYHHLGATSPKVVCTELATGTRCPGGPWPKVLNTAPGPLGTLGAGDIATTMVEQYVRDPASPAKVYYPAVTAASVGVACLDMAASANCGYWALAATGGSPAVSGITGFVETGGNLYGLISSGAVVCWTIATQSACGGQPYAPIAPPISGNPYVYGALDVVAGKVFASSSNPGTAQVPSLGCFDPATATACAGWASWRPTGPAGNFTYNAYTAFGTTGAPVGVCSSTTGGTNVTTCYALDGSALPAPPGAAALPNGTYVFNPEVVTDPSGHVRSYLPVWNGGIAGAAVCHDWTTGAACAGLPARITHPSVNGGATRDYGYAYDPPSGCLIGLGDAGVLFSMDPITGATPCVRSGGQVTLRPGDFYCDGGSHVQGYTSARLTGVDPANVDFAASRVTVVDSGGAVVPTPGFAPDGSVDLTGVSVAAHPSITVTTTLVLHSAAGFSGSLVVDFAGDAPQLCFRTTLSADCTVTSVANTATGTDSTGSFSSNTVTLPVAPGASCTPKVTVEKEICTAVHPAECGPGGAGPWAKQAPVGLLGVLAASAYWRITVTNQGPVGITSAQVVDTVEPSCQTGPFTLAAGQSKQVYCATYALLNLFPITNKAKVSYVPVNVPPGTPPSTTDWSAAKACSLLCSL
>NC_017186.1|WP_013225172.1|3576525_3577290_+|MHYT-domain-containing-signal-sensor
MEHFALGHWLLVLAYLTSVVGCALGLACAVQARHAADPRHRVRWLVLAAVSIGGVGIWLMHFVAMLGFSTPGMPVRYDIFRTVLSAILSVVAVFAGLVVVGGRAKFGWWRLALGGVITGLAVNVMHYTGMSALRVKGDFGYDGGLVALSVVIAVVAATAALWFAVFLDRLALRLLAGFVMGAAVTGMHYTGMAAVRMTMDANAPDPAGAEVFSFLFPVFVLAAIAMAVPLCAVLMAPAVSPEAAESGVEDAVAV
>NC_017186.1|WP_013225171.1|3576131_3576512_+|DUF742-domain-containing-protein
MIDDAPGDEPRRSPALARPYAWTEGRTAPAVEIAVEALVETTADGRAEAVYQTSSALAEVLELCVRPRSLMEIAALLALPLGVVRVLVSDLMQDYLVIVRDTLSDTATWDERHDLMERVLHGLRDL
>NC_017186.1|WP_013225170.1|3575649_3576135_+|roadblock/LC7-domain-containing-protein
MTELHPRRSATEPAARSLRGTLPAPPERSATLNWLVNGFVQDVSGVAHAVLVSADGLLVAADDSLPRERGDQLAAIAAGLSSLSLGTAELFTAGRVVQSVIEMEQGFLLLMSVGDGSNLVVLASTGCDIGLVGYEMTMLVERVGQKVDVPAREIPVAQDHR
>NC_017186.1|WP_013225168.1|3571241_3572489_-|low-temperature-requirement-protein-A
MTDVDEGGKRVGWVELYFDLVFVFAVGQVAHGIVADPHWARAAAALGLFATLWWTWIGFAVLYNRRGDDSRVADRLFVLAGTIPCGIAATQAHHVFEGHPAIFAAAMAAVRLILAAAHRWPRDGIDQRRISVGYAVSAVLFGVSAALPHSWASWALWAVALLQEAGFLLLGDHRERRRGERPTREARWRIMLAPPRDPNLAVDSAHLAERFGLFMILLLGELVITVGTAALERPADDLGYWLALAGGLVLAGALWWVYFSSAAEIYERMLGFSGGNPALAYSLYAGGHLLPAFALVLMAAGVNLSLAESPPTAAVWFTTAGLTIYLAGTRVFAMGSHRWYFGLARVAALAATASLAFLDRLLPAPAVVLVIAVWAAGTAAVTTVIRRRSLTDLGDDPVAFLRQAADRHRDSGSRG
>NC_017186.1|WP_013225167.1|3570660_3571137_+|MarR-family-transcriptional-regulator
MTQTWQEHDGADAALAALRAMVLIADSTVERNTEQLTLTQFRALRVVVDRTPVTMGRVARELAMNPSSVTRACDRLVALNLLEKAPNPLNRRETLLAPAGPGRQLVDRVDRDRRRVLAGVLSRLDPATRAAAITAFERFAGAVEADESDSRSLLRRAN
>NC_017186.1|WP_013225166.1|3568741_3570535_-|thiamine-pyrophosphate-requiring-protein
MSQTVGDYLLQRLREWGVEQVFAYPGDGINGIVASFGKADNQPRFVQARHEEMAAFAAVGYAKFSGKVGVCMATSGPGAIHLLNGLYDAKLDHVPVVAIVGQTARSAMGGSYQQEVDLQALFKDVASEYLVEVNVPEQLPNALDRAIRTAEASRCPTALIIPADLQEEAYSPPQHAFKQVPSSPPGTSWSRPVPAEADIDAAAEVLNAGEKVAILVGQGARGAAQEVREVAEITGAGVAKALLGKDVLPDDLPWVTGSIGLLGTRPSYELMRDCDTLLIVGSNFPYSQFLPDFGQARAVQIDLDGRLIGMRYPTEVNLVGDSAATLRALLPKLASKPDRAWRETIEKNVASWWETVEKEAAVEADPVNPMAIVSELSKRIPENAIVTADSGSSTNWYARNLRIRGDIRGSLSGTLATMGPAVPYAIGAKFAHPDRPVIALVGDGAMQMNGLAELITIARYHTLWSDPRLVICVFHNNDLNQVTWELRAMGGAPKFEESQTLPDVDYASFALSLGLAAVTVDKPDQLASAWDTALTAGKPAVLDVRCDPDVPPIPPHATFEQVKSATEAVLKGDPDAFHLVVQGVKTKLQEFLPGKNR
>NC_017186.1|WP_176742152.1|3567387_3568386_-|SDR-family-NAD(P)-dependent-oxidoreductase
MNQVVVVTGASGGIGRAVARAFGARQARVALLARGKEGLEAAADDVTRSGGTALAIPTDVAEFDQVDAAASRVERELGPIDVWVNVAFTSVFAPFDEIEPDEFRRVTDVSYLGYVHGTMAALRRMKSRDRGTIVQVGSALAYRGIPLQSAYCGAKHAIQGFNEALRCELLHDGSHVRTTMVQMPAVNTPQFSWVRSKLPHQAQPVPPIYQPEVAARAVLHAADHPRRREYWVGGSTVGTLIANAVAPGVLDRYLARTGYRSQQTGAAKPSDQPENLWAPADRARDFGAHGRFDDKATPRSAQLWASRHHGAVAAAGGALAATALAVWRRARS
>NC_017186.1|WP_013225164.1|3566648_3567086_-|hypothetical-protein
MKFTAKRVAVSGAVAGVAVVAVGATVIATAADPVSPEVVSAVPADAGHGDEGKYTTGDYVLNVHELDDDGDGITTAIGPHTMYYSKTLHGSGNRKATVVKFSAGPDSDASIVFSYPVPAPGRVVDCTASGTETAPQVRCETKPAR
>NC_017186.1|WP_013225175.1|3580978_3582469_-|family-20-glycosylhydrolase
MLIPRPAQLTRRAGSCVPTGILAGPGTRGPARLLAAYTGLPLVPDGPVIRLARKPGLGPEEYTLEVTPGRALLTASTDAGLLAGVQTIRQLHPRLPCLTIRDAPRLLWRGVLLDVARHFMPLSFLREFVDLLALHKFNVLHLHLTDDQGWRIEIDRRPRLTEVGAWRAESMVGPAGSGVFDGVPHGGFYTQRELRDLVAFAAERGVRIVPEIDLPGHVRAALAAYPSLGNRPSVALPVWTEWGISPDILGVHDEAFAFCRDVLTQVAGVFPAPYLHIGGDECPTTQWETSPVARATAASLGVRPAELHPWFLGRLHDIVAELGRRAVCWDETGHAAGRLPADLVVTAWRDPAHGALAVARGHQVVMAPHTSTYFDYRQSEDPGEPPRGPVTTLEDVYRFDPLAGGLPVSDGTAPGVLGTQAQLWTEHAPTPEHVRHLAFPRLCALAERAWSPPGRGYADFHQRLAGHLDRLRALGALPKERVRFAGALGVSGKTVP
>NC_017186.1|WP_013225176.1|3582468_3583287_-|carbohydrate-ABC-transporter-permease
MIRRIGRNVTAAVFCLVWIFPVYWMVLTAFKPAGKILSPTPEFLPLDVTLDNFAGALAKPGFVQDLANSVVVVVSVVVLSIVVAFLAATALTRFRFFGRRSFLIGVLVLQMVPVPALVIPLFLGLKSAHLLDTLPGLILTYVALVLPFTIWTLRGFLHGIPVELEEAAMVDGATRGRVMRSVLLPLVLPGLIATSVFAFITAWNDFLFAYVIMKDSSGYTLPVWLVSFSTSTGTDYGGLIAASTLFALPVVVFFALVQRHLVEGMTAGAVKG
>NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease
MLLEKAPTRERTPRVSLLPYGLLLPAAALLGLVLGYPLVRLVVISLQEYGLRSLFTGTTRFAGGDNYAAVLADPQLLPVLGRSLGFCAALVAGTLVIASGVALLLQRLGRRMRTAVTLSLIAAWALPNVASTLVWQWLFQPGYGVVNWLLTRLGFGDLTQHDWTTSPASAFTLVWLLVVWQSVPFAALTLHAGLSQIPRSYYEAAALDGAGPWRVHRTITVPFLQPILGLVTILSVIWDFTVFNQIWILTQGGPGGGTTTLGIWTFTRAFSRNDFGQGAAIAVVSVALLAGLTAVYVRRLVRSGEDL
>NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein
MARPRPLLTTQELPVRRPVLAAVLAVAAVTATACGTDTPAPAARGGELTVWLMNGDLSDKATAAITTAFEKATGAKVTVQIQEWDNINTKISTALAQDSTPDVIEIGNTDVPLFAANGALTDLNPHRDELAAGQTWLPGLAGPATVDGHLYGAPLFAGNRAVIYDKQVWADAGVTAPPKTLPELTAALDKIKAKHPAPDYSAFHFPGRYWFGALQFVWDAGGQLATQRAGKWAGALESPEALKGLQAWKDFQNAYSSPASRNVDTKAPDQAAIFSAGGAAAILDTSVNTVLKNKPELKDRLGTFPFPSGTPGKTQPVFLGGSDVVVAAKSRNSDLALAYLKAATDPAVQRDAIAGIDGWTPISTELIDRITPALPPLNAAFATAAKTSVATPAAPGWATIESDKSINTFFADIATGRRPIADAAKEFDAHLTEALGAR
>NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase
MSRSSIRTTTAALTSLATAATAALVLSGGADASPASAAAGCGVLFDDFHYSSPTDGAFGGAGWTTRNDVGSPGVPGARWLTSNISFPAVNGERVAQLTATTDGSAAGTTHAELYQNQLRFFEGTYASRVRFTDAPDSGPDGDHVNETYFTISPLRYDRDPLYSELDFSEYLPNGGWGGSTANYQTSWYTYWNNPTWDGLRTSTAQNRSFAGWHDVVTQVSGGHVKYYIDGVLTADHTTDAQGDPVYPRTPMSINYNMWFIDTAGHTSGTSAYTEQVDWTYYAGNQVVSPADAVAQAGQYRSAGTSHVDSVNGCSTPTTPPATTTPTTTPTTPTTPTTPSQPANCSSAAEWDWGTMYLEGQRVKHNAHLWQANWWTQGSEPGLTAQWRDLGHC
>NC_017186.1|WP_013225180.1|3586884_3587832_-|pyridoxal-phosphate-dependent-enzyme
MPEMRLDLARIRAAREVIDPVFLDTPLYRCEALEPVLGCAVSIKLETANPVRSFKGRGTEVVASRLAGPVVCASAGNLGQALAWSGRGRGLDVTVVASRHATAAKLERIRALGARLELVDGDHELARERAATIARRDGSRLVEDSLDLETCEGAATIGLELVDATPTFDAVLLALGGGALATGVGHVVRSGAPGTEVICVQPAGAPAMTRSWHARRVVTTGPTATIADGVAGRRPIPEVLADLLVVADNAVLVTEASIITGMRLLLEHAGLVAEPSAALGIAAILEDRDRFAGRHVVTVVCGGNVDLSAYRDWVR
>NC_017186.1|WP_013225181.1|3587841_3588216_-|VOC-family-protein
MSEQYAGVRYVVDDVQAALDFYTTHLGFTVRMSAAPAFADVVRGPLRLLLSGPASSGARATPADASAAGRNRIHLVLDDLDAEITRLTDAGVAFRTEVVSGPGGRQILLADPAGNLVELFQPAH
>NC_017186.1|WP_013225182.1|3588212_3588935_-|ArsR-family-transcriptional-regulator
MASEPPAFVRLAAHPLRWALLTALAGGDLRVRELVERVGEPQNLVSYHLRLLRGGGLVTAARSSFDGRDSYYHLDLDRCAGALAEAGAALHPTLDPAPRPQVPPPRPVAVLFLCTGNSARSPIAEALLRRRAAGAVTVTSAGSHPKAALHPGAIRALEEFGIDVRGQRPRHLDTVAGQRFDHVITVCDKVREVCPEFPHHPRRRHWSIPEPGSFPETAAELDTRVRHLLPELVPGKEVRP
>NC_017186.1|WP_013225183.1|3589013_3590168_+|isovaleryl-CoA-dehydrogenase
MAGLTEEEAAIVAVVRDFVDHDVRPVVRELDHTDTYPEALIERMKELGVFGLAVPEAWGGTPVSARCYAEVTEELACGWMSLAGAMGGHTVVAKLIVTYGTREQQERYLPRMATGEVRATMALTEPGGGSDLQALRTTARRAGESYVVDGAKTWITNARRSQLVALLCKTDPHAEPAHAGISILLAEKGAGFHVSRDLPKLGYKGVESCELSFSDFRVPVGALLGGEEGRGFAQMMRGLEIGRIQVAARALGVGRAALADSLRYAQERETFGKPIWQHQSVGNLLADMATKLEAARQLVHHAARRYDSGARADLEAGMAKLFASETAMEIALNAVRVHGGYGYSTEFDVERYFRDAPLMIVGEGTNEIQRTVITRQLIRRHRLG
>NC_017186.1|WP_013225184.1|3590543_3592838_-|LuxR-family-transcriptional-regulator
MGARSRRSAGNLPAELTSFVGRRHELGEAKRLLATARLVTLTGAGGVGKTRLALRVAADVRRAFPDGVWLVELADVGDPHLVPNTVATAFGLRVTSDQAAGLAEYLEDKQLLLVLDNCEHVADECATLVAKLLAVSAGLRVLATSRHTLHVEGEHLLHVEPLPVPGDEDAGGGPVEAVTLFADRAAAVSPGFELTPDNRATVSRICRRLEGIPLAIELAAVRVRVLAVDQVLERLDDRLGLLTSRPAAVQPRRRTLEAAIDWSFELCTPAEQRLWAQASVFPGGFDLDAAEGVCVPAADGGSALDVVAGLVDKSVLSRQNGTFGRHAWYRMLETVREYGGARLAAGGDEAGVRARQAGYYADLARRYRAEGFGPRQSEWLGRLRREHANLRAVLEHCLSGPGQASQALDIAASLWNFWYGGGLVPEGCGYLRRGLELCGERTLVRARGLYAMAFLAIQTGAPHAQLLAELDELAEELGDERLRAGHAECAGMATFFTGDLSGGAELLERALAGYRTAGDPLLVFDTLILLAAARFFLGDPRGAAAAEEALALTDRHQARWSRGYALWAVAIHRWRAGEPRQATDLLHEAVALRLPDRTLLAFLVEALAWCHSAEGEHDRVARLLGGAGAVWRLSGARVGEMSPYQAVDEQCAALARKALGEDAFAAAFAEAAGSGLDDVVRYALRERPATRAAGKAAEPGGLTRRQREIAELVARGMSNKEIAAALVLSGRTVEGHVENILVKLGLTSRTQVASWLAGQPGRPA

Crispr_ID: NC_017186_12

• CRISPR_ID: NC_017186_12
• CRISPR_location: 3575110-3575207
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_12

Consensus_repeat	Method
GGACCGGATCGCTCCGGTCGAGG	CRISPRCasFinder

spacers of NC_017186_12

>12.1|3575133|52|NC_017186|CRISPRCasFinder
GCGCCCGAGCAGAGACTCGCGCGGTGCATGGGACCGGTTCGGCGGAGCCGGC

CRISPR arrays and Neighbor proteins around NC_017186_12

CRISPR arrays

The CRISPR arrays of NC_017186_12

>merge|NC_017186|12|3575110-3575207|CRISPRCasFinder
GGACCGGATCGCTCCGGTCGAGGGCGCCCGAGCAGAGACTCGCGCGGTGCATGGGACCGGTTCGGCGGAGCCGGCGGACCGGATCGCTCCGGTCGAGG

>NC_017186|12|11|3575110-3575207|CRISPRCasFinder
GGACCGGATCGCTCCGGTCGAGG	GCGCCCGAGCAGAGACTCGCGCGGTGCATGGGACCGGTTCGGCGGAGCCGGC
GGACCGGATCGCTCCGGTCGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270450
NC_017186.1|WP_176742152.1|3567387_3568386_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235935
NC_017186.1|WP_013225174.1|3580121_3580820_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225099
NC_017186.1|WP_013225168.1|3571241_3572489_-|low-temperature-requirement-protein-A	unknown	unknown	gnl|CDD|377704
NC_017186.1|WP_013225172.1|3576525_3577290_+|MHYT-domain-containing-signal-sensor	unknown	unknown	gnl|CDD|225837
NC_017186.1|WP_013225159.1|3560893_3562738_+|RICIN-domain-containing-protein	unknown	unknown	gnl|CDD|379501
NC_017186.1|WP_013225166.1|3568741_3570535_-|thiamine-pyrophosphate-requiring-protein	unknown	unknown	gnl|CDD|181344
NC_017186.1|WP_013225160.1|3562759_3563941_-|DUF2236-domain-containing-protein	unknown	unknown	gnl|CDD|378343
NC_017186.1|WP_013225163.1|3565832_3566645_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013225175.1|3580978_3582469_-|family-20-glycosylhydrolase	unknown	unknown	gnl|CDD|119333
NC_017186.1|WP_013225167.1|3570660_3571137_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase	unknown	unknown	gnl|CDD|185683
NC_017186.1|WP_013225164.1|3566648_3567086_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013225161.1|3564110_3565268_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NC_017186.1|WP_013225170.1|3575649_3576135_+|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|224929
NC_017186.1|WP_013225171.1|3576131_3576512_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NC_017186.1|WP_013225176.1|3582468_3583287_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_017186.1|WP_013225162.1|3565317_3565836_+|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NC_017186.1|WP_013225173.1|3577331_3579728_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.3641e-98
NC_017186.1|WP_176742152.1|3567387_3568386_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|235935	PRK07109, PRK07109, short chain dehydrogenase; Provisional.	2.63382e-174
NC_017186.1|WP_013225174.1|3580121_3580820_-|GntR-family-transcriptional-regulator	gnl|CDD|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.24644e-56
NC_017186.1|WP_013225168.1|3571241_3572489_-|low-temperature-requirement-protein-A	gnl|CDD|377704	pfam06772, LtrA, Bacterial low temperature requirement A protein (LtrA). This family consists of several bacteria specific low temperature requirement A (LtrA) protein sequences which have been found to be essential for growth at low temperatures in Listeria monocytogenes.	3.52367e-56
NC_017186.1|WP_013225172.1|3576525_3577290_+|MHYT-domain-containing-signal-sensor	gnl|CDD|225837	COG3300, COG3300, MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms].	1.47748e-32
NC_017186.1|WP_013225159.1|3560893_3562738_+|RICIN-domain-containing-protein	gnl|CDD|379501	pfam14200, RicinB_lectin_2, Ricin-type beta-trefoil lectin domain-like.	7.01987e-21
NC_017186.1|WP_013225166.1|3568741_3570535_-|thiamine-pyrophosphate-requiring-protein	gnl|CDD|181344	PRK08273, PRK08273, thiamine pyrophosphate protein; Provisional.	0
NC_017186.1|WP_013225160.1|3562759_3563941_-|DUF2236-domain-containing-protein	gnl|CDD|378343	pfam09995, DUF2236, Uncharacterized protein conserved in bacteria (DUF2236). This domain, found in various hypothetical bacterial proteins, has no known function. This family contains a highly conserved arginine and histidine that may be active site residues for an as yet unknown catalytic activity.	1.10886e-09
NC_017186.1|WP_013225175.1|3580978_3582469_-|family-20-glycosylhydrolase	gnl|CDD|119333	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	5.01817e-169
NC_017186.1|WP_013225167.1|3570660_3571137_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.96098e-11
NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.76092e-71
NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase	gnl|CDD|185683	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16. The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.	3.03408e-15
NC_017186.1|WP_013225161.1|3564110_3565268_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	2.23477e-13
NC_017186.1|WP_013225170.1|3575649_3576135_+|roadblock/LC7-domain-containing-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	1.27529e-21
NC_017186.1|WP_013225171.1|3576131_3576512_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	2.02345e-25
NC_017186.1|WP_013225176.1|3582468_3583287_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.85483e-80
NC_017186.1|WP_013225162.1|3565317_3565836_+|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	2.1648e-46

Protein sequences

>NC_017186.1|WP_013225168.1|3571241_3572489_-|low-temperature-requirement-protein-A
MTDVDEGGKRVGWVELYFDLVFVFAVGQVAHGIVADPHWARAAAALGLFATLWWTWIGFAVLYNRRGDDSRVADRLFVLAGTIPCGIAATQAHHVFEGHPAIFAAAMAAVRLILAAAHRWPRDGIDQRRISVGYAVSAVLFGVSAALPHSWASWALWAVALLQEAGFLLLGDHRERRRGERPTREARWRIMLAPPRDPNLAVDSAHLAERFGLFMILLLGELVITVGTAALERPADDLGYWLALAGGLVLAGALWWVYFSSAAEIYERMLGFSGGNPALAYSLYAGGHLLPAFALVLMAAGVNLSLAESPPTAAVWFTTAGLTIYLAGTRVFAMGSHRWYFGLARVAALAATASLAFLDRLLPAPAVVLVIAVWAAGTAAVTTVIRRRSLTDLGDDPVAFLRQAADRHRDSGSRG
>NC_017186.1|WP_013225167.1|3570660_3571137_+|MarR-family-transcriptional-regulator
MTQTWQEHDGADAALAALRAMVLIADSTVERNTEQLTLTQFRALRVVVDRTPVTMGRVARELAMNPSSVTRACDRLVALNLLEKAPNPLNRRETLLAPAGPGRQLVDRVDRDRRRVLAGVLSRLDPATRAAAITAFERFAGAVEADESDSRSLLRRAN
>NC_017186.1|WP_013225166.1|3568741_3570535_-|thiamine-pyrophosphate-requiring-protein
MSQTVGDYLLQRLREWGVEQVFAYPGDGINGIVASFGKADNQPRFVQARHEEMAAFAAVGYAKFSGKVGVCMATSGPGAIHLLNGLYDAKLDHVPVVAIVGQTARSAMGGSYQQEVDLQALFKDVASEYLVEVNVPEQLPNALDRAIRTAEASRCPTALIIPADLQEEAYSPPQHAFKQVPSSPPGTSWSRPVPAEADIDAAAEVLNAGEKVAILVGQGARGAAQEVREVAEITGAGVAKALLGKDVLPDDLPWVTGSIGLLGTRPSYELMRDCDTLLIVGSNFPYSQFLPDFGQARAVQIDLDGRLIGMRYPTEVNLVGDSAATLRALLPKLASKPDRAWRETIEKNVASWWETVEKEAAVEADPVNPMAIVSELSKRIPENAIVTADSGSSTNWYARNLRIRGDIRGSLSGTLATMGPAVPYAIGAKFAHPDRPVIALVGDGAMQMNGLAELITIARYHTLWSDPRLVICVFHNNDLNQVTWELRAMGGAPKFEESQTLPDVDYASFALSLGLAAVTVDKPDQLASAWDTALTAGKPAVLDVRCDPDVPPIPPHATFEQVKSATEAVLKGDPDAFHLVVQGVKTKLQEFLPGKNR
>NC_017186.1|WP_176742152.1|3567387_3568386_-|SDR-family-NAD(P)-dependent-oxidoreductase
MNQVVVVTGASGGIGRAVARAFGARQARVALLARGKEGLEAAADDVTRSGGTALAIPTDVAEFDQVDAAASRVERELGPIDVWVNVAFTSVFAPFDEIEPDEFRRVTDVSYLGYVHGTMAALRRMKSRDRGTIVQVGSALAYRGIPLQSAYCGAKHAIQGFNEALRCELLHDGSHVRTTMVQMPAVNTPQFSWVRSKLPHQAQPVPPIYQPEVAARAVLHAADHPRRREYWVGGSTVGTLIANAVAPGVLDRYLARTGYRSQQTGAAKPSDQPENLWAPADRARDFGAHGRFDDKATPRSAQLWASRHHGAVAAAGGALAATALAVWRRARS
>NC_017186.1|WP_013225164.1|3566648_3567086_-|hypothetical-protein
MKFTAKRVAVSGAVAGVAVVAVGATVIATAADPVSPEVVSAVPADAGHGDEGKYTTGDYVLNVHELDDDGDGITTAIGPHTMYYSKTLHGSGNRKATVVKFSAGPDSDASIVFSYPVPAPGRVVDCTASGTETAPQVRCETKPAR
>NC_017186.1|WP_013225163.1|3565832_3566645_+|hypothetical-protein
MNTEQENRLREDLRLAVDGETFRTDPDVVLGRARRARRRSLVTRGAAGTGVLAVAVAAALTGIHPGGAPEVRTAAYVVERISAALDGGSDSVYRIVDHNEGSVWYQDQVTMSQYWVYGTGGTRIEAWDSTPVIDHYAHLVDTTVNHKDRTYSTEDTKLPAYVPGTLPPRSSFADRIKKSISAGGPEIAGSGEYQGHQVIKLGYPGGELWVDSATYLPVYRITTDPDGRRTTSDLAFLPRTPDLVQTVNTPQVPPGFTKVAEANTGPGHGG
>NC_017186.1|WP_013225162.1|3565317_3565836_+|SigE-family-RNA-polymerase-sigma-factor
MKQTEDAEPGRDAEFREFVRSRGTPLHRSAYLLCGDRHLADDVVQDTLVKVYQHWRRVRQADSPEAYVRRILLNEVRGRWRRRERSVPVAEFADEPAVADPSDDVIRRDGLRQALLTLPLRQRATVVLRYLEGLSERETAAVLGCSTGTVKSQSSRALAGLKSFFDRTGTML
>NC_017186.1|WP_013225161.1|3564110_3565268_+|TetR/AcrR-family-transcriptional-regulator
MTAEPAAAVRPRNRRQLIVEAGAAVFGERGYHAASMDEIAARVGITAAALYRHFPNKYALFAACANVMADRLVAALAEVAPDASLAEIFAAVTRVTVAHRETGGVYRWEARYLEREDRRLLAGKFADVVERVAAAVRREHPWPGEHLRAVAALGAIGSVTTHHNAMAQRRVGELLRAAALRVAATGPAAAHAPLVEIPAPPVPRTRRSEILAAAVPLFERDGFATVTNGRIAEAVGLVPSALYRYFPGKADILAAACLQAAGLLAQAVEHNLRGTTDPHGALSALTATYVAYSFEHSALNSVANAEIAGLPDGLRRPLVAAQREHIAVWEQHLREARPDLDARQARVLVHAGFGVVVEAGRRLRWADRPEHRAAVAALLVSALGL
>NC_017186.1|WP_013225160.1|3562759_3563941_-|DUF2236-domain-containing-protein
MSNLSRRNALSLGVALGLVGAASVVPAWASTAAADPWWVWDDEVDRLMAGVLDTGGVPAVNTALRSWVDNADPLPSGLPADLAAWLQGVNRLPSWADPVKLRRAADFNRRKDTYLFVLYGLGSGIMSTVIPREARSVYWSAGGAAMQDRAAKTFTFGYDLSEAGAFEPSGQFVVTANKTRLVHAAVRHLLPQSPHWRAVADERVPISNGDILVTFHSLGTFVHRKLKEWHVPMSAADEDAFLHQWQVAIHLLGVRDEFIPQTWAAADTQSAQVLTPLLAPTPEGKQLAADLLGLTAQIDLGVTRGFLNEFVRYVLSNEVGDWLGLPRDYAAATLIRTGWPAYIAFREGLLPIAPAAFHLFDQFVRALAMLFLNKGTSPTSTPITIPAGNRPGA
>NC_017186.1|WP_013225159.1|3560893_3562738_+|RICIN-domain-containing-protein
MDLSRQRPRVRRGLAALLITGALTGASAVALPAPAQAADESVSVDFSAAGGAPTYRASGWIYGMTENASGPPDHFYRDVNFQAMRAGGAQLDSPGGWVSGKYDRRWNATRAQLLRTRSLGGQFVLLVHDLWGADGYPISRFPGDNGDWTDYDNFLTRLIGDVRATGAPVEWDIWNEPNISLFWNRPQSQYFAMWQRAYQRIRAAFPAQAIVGPSLAGVPSTAGSWWTQYLDFVRGSNTVPDIVSWHSLPGDPVANVAAADASLGSRGIPHPRPYQINEYGASNEQNPGDGAWYIARLERAGADGLRANWASAGNLHNDLANLLVRTSSGRYQPKGEWWAYRFYASQTGQLVATKPSPGYDPFATKAAGMAKVLVGGGGTTGNVAVALQRLDTTSGVVQNNQVRVIVQRIPYNGGAAVQSPVTIQDSVAAVSGNAVTVNLPHTTIDDALSITLLPPSDGGFQSVAVAQHSQQCLDNTDLSTADGNRQQQDVCDGGAQQQWNFRPVAGVPGAYAIVNQQSGKCLEVAGASAADGAAVQQRTCTDGATNQQFSPRRVTYGGNDPHDYQLVARHSGKCVDVSGVSTAARGAVIQWTCKPVSQNSPLNQTWRLWGRGPA
>NC_017186.1|WP_013225170.1|3575649_3576135_+|roadblock/LC7-domain-containing-protein
MTELHPRRSATEPAARSLRGTLPAPPERSATLNWLVNGFVQDVSGVAHAVLVSADGLLVAADDSLPRERGDQLAAIAAGLSSLSLGTAELFTAGRVVQSVIEMEQGFLLLMSVGDGSNLVVLASTGCDIGLVGYEMTMLVERVGQKVDVPAREIPVAQDHR
>NC_017186.1|WP_013225171.1|3576131_3576512_+|DUF742-domain-containing-protein
MIDDAPGDEPRRSPALARPYAWTEGRTAPAVEIAVEALVETTADGRAEAVYQTSSALAEVLELCVRPRSLMEIAALLALPLGVVRVLVSDLMQDYLVIVRDTLSDTATWDERHDLMERVLHGLRDL
>NC_017186.1|WP_013225172.1|3576525_3577290_+|MHYT-domain-containing-signal-sensor
MEHFALGHWLLVLAYLTSVVGCALGLACAVQARHAADPRHRVRWLVLAAVSIGGVGIWLMHFVAMLGFSTPGMPVRYDIFRTVLSAILSVVAVFAGLVVVGGRAKFGWWRLALGGVITGLAVNVMHYTGMSALRVKGDFGYDGGLVALSVVIAVVAATAALWFAVFLDRLALRLLAGFVMGAAVTGMHYTGMAAVRMTMDANAPDPAGAEVFSFLFPVFVLAAIAMAVPLCAVLMAPAVSPEAAESGVEDAVAV
>NC_017186.1|WP_013225173.1|3577331_3579728_-|hypothetical-protein
MRRRILGAVLPLVLTTAVAVPLPAAADPAPAVSALTKSVQRTGSPAAHGATANWVVGYEDHATTTGAAAITDAVGAGQAYQSGSLHVPPGWTPEWSTDGSTFAGAEPASGVTAVRATNPAAGPDATQLTGALTPPVQAVTTATGGDGFSPILYRTPGGSLQAWNIYHHLGATSPKVVCTELATGTRCPGGPWPKVLNTAPGPLGTLGAGDIATTMVEQYVRDPASPAKVYYPAVTAASVGVACLDMAASANCGYWALAATGGSPAVSGITGFVETGGNLYGLISSGAVVCWTIATQSACGGQPYAPIAPPISGNPYVYGALDVVAGKVFASSSNPGTAQVPSLGCFDPATATACAGWASWRPTGPAGNFTYNAYTAFGTTGAPVGVCSSTTGGTNVTTCYALDGSALPAPPGAAALPNGTYVFNPEVVTDPSGHVRSYLPVWNGGIAGAAVCHDWTTGAACAGLPARITHPSVNGGATRDYGYAYDPPSGCLIGLGDAGVLFSMDPITGATPCVRSGGQVTLRPGDFYCDGGSHVQGYTSARLTGVDPANVDFAASRVTVVDSGGAVVPTPGFAPDGSVDLTGVSVAAHPSITVTTTLVLHSAAGFSGSLVVDFAGDAPQLCFRTTLSADCTVTSVANTATGTDSTGSFSSNTVTLPVAPGASCTPKVTVEKEICTAVHPAECGPGGAGPWAKQAPVGLLGVLAASAYWRITVTNQGPVGITSAQVVDTVEPSCQTGPFTLAAGQSKQVYCATYALLNLFPITNKAKVSYVPVNVPPGTPPSTTDWSAAKACSLLCSL
>NC_017186.1|WP_013225174.1|3580121_3580820_-|GntR-family-transcriptional-regulator
MKRDRVRRHLLKVIENAGPGTGLASERDLAAELGVSRPTVRAAIDELTRTGLLVRQRGRGTFTSPHKVTQELATGLAVPPAEGHWTSRVVAFAVSPAPRTLAGELELEPGAPVLRVTRVRYVDDEPIAIESLALPAALVPGLRPADLEAGNFYRLLRERFGIAVQDAVQTIEPAVTDPGQAELLEIAVYAPILHIERLTRDTTGRIVELTRSSYRGDRYRITSKLRFDAESG
>NC_017186.1|WP_013225175.1|3580978_3582469_-|family-20-glycosylhydrolase
MLIPRPAQLTRRAGSCVPTGILAGPGTRGPARLLAAYTGLPLVPDGPVIRLARKPGLGPEEYTLEVTPGRALLTASTDAGLLAGVQTIRQLHPRLPCLTIRDAPRLLWRGVLLDVARHFMPLSFLREFVDLLALHKFNVLHLHLTDDQGWRIEIDRRPRLTEVGAWRAESMVGPAGSGVFDGVPHGGFYTQRELRDLVAFAAERGVRIVPEIDLPGHVRAALAAYPSLGNRPSVALPVWTEWGISPDILGVHDEAFAFCRDVLTQVAGVFPAPYLHIGGDECPTTQWETSPVARATAASLGVRPAELHPWFLGRLHDIVAELGRRAVCWDETGHAAGRLPADLVVTAWRDPAHGALAVARGHQVVMAPHTSTYFDYRQSEDPGEPPRGPVTTLEDVYRFDPLAGGLPVSDGTAPGVLGTQAQLWTEHAPTPEHVRHLAFPRLCALAERAWSPPGRGYADFHQRLAGHLDRLRALGALPKERVRFAGALGVSGKTVP
>NC_017186.1|WP_013225176.1|3582468_3583287_-|carbohydrate-ABC-transporter-permease
MIRRIGRNVTAAVFCLVWIFPVYWMVLTAFKPAGKILSPTPEFLPLDVTLDNFAGALAKPGFVQDLANSVVVVVSVVVLSIVVAFLAATALTRFRFFGRRSFLIGVLVLQMVPVPALVIPLFLGLKSAHLLDTLPGLILTYVALVLPFTIWTLRGFLHGIPVELEEAAMVDGATRGRVMRSVLLPLVLPGLIATSVFAFITAWNDFLFAYVIMKDSSGYTLPVWLVSFSTSTGTDYGGLIAASTLFALPVVVFFALVQRHLVEGMTAGAVKG
>NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease
MLLEKAPTRERTPRVSLLPYGLLLPAAALLGLVLGYPLVRLVVISLQEYGLRSLFTGTTRFAGGDNYAAVLADPQLLPVLGRSLGFCAALVAGTLVIASGVALLLQRLGRRMRTAVTLSLIAAWALPNVASTLVWQWLFQPGYGVVNWLLTRLGFGDLTQHDWTTSPASAFTLVWLLVVWQSVPFAALTLHAGLSQIPRSYYEAAALDGAGPWRVHRTITVPFLQPILGLVTILSVIWDFTVFNQIWILTQGGPGGGTTTLGIWTFTRAFSRNDFGQGAAIAVVSVALLAGLTAVYVRRLVRSGEDL
>NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein
MARPRPLLTTQELPVRRPVLAAVLAVAAVTATACGTDTPAPAARGGELTVWLMNGDLSDKATAAITTAFEKATGAKVTVQIQEWDNINTKISTALAQDSTPDVIEIGNTDVPLFAANGALTDLNPHRDELAAGQTWLPGLAGPATVDGHLYGAPLFAGNRAVIYDKQVWADAGVTAPPKTLPELTAALDKIKAKHPAPDYSAFHFPGRYWFGALQFVWDAGGQLATQRAGKWAGALESPEALKGLQAWKDFQNAYSSPASRNVDTKAPDQAAIFSAGGAAAILDTSVNTVLKNKPELKDRLGTFPFPSGTPGKTQPVFLGGSDVVVAAKSRNSDLALAYLKAATDPAVQRDAIAGIDGWTPISTELIDRITPALPPLNAAFATAAKTSVATPAAPGWATIESDKSINTFFADIATGRRPIADAAKEFDAHLTEALGAR
>NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase
MSRSSIRTTTAALTSLATAATAALVLSGGADASPASAAAGCGVLFDDFHYSSPTDGAFGGAGWTTRNDVGSPGVPGARWLTSNISFPAVNGERVAQLTATTDGSAAGTTHAELYQNQLRFFEGTYASRVRFTDAPDSGPDGDHVNETYFTISPLRYDRDPLYSELDFSEYLPNGGWGGSTANYQTSWYTYWNNPTWDGLRTSTAQNRSFAGWHDVVTQVSGGHVKYYIDGVLTADHTTDAQGDPVYPRTPMSINYNMWFIDTAGHTSGTSAYTEQVDWTYYAGNQVVSPADAVAQAGQYRSAGTSHVDSVNGCSTPTTPPATTTPTTTPTTPTTPTTPSQPANCSSAAEWDWGTMYLEGQRVKHNAHLWQANWWTQGSEPGLTAQWRDLGHC

Crispr_ID: NC_017186_14

• CRISPR_ID: NC_017186_14
• CRISPR_location: 3595321-3595412
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_14

Consensus_repeat	Method
TCACCAGCCTTTGTCGCTCATCG	CRISPRCasFinder

spacers of NC_017186_14

>14.1|3595344|46|NC_017186|CRISPRCasFinder
TGCGCTCCTTCCCGGTGGCAGGGGAGTGGGACTCGGTCGCCGGGGT

CRISPR arrays and Neighbor proteins around NC_017186_14

CRISPR arrays

The CRISPR arrays of NC_017186_14

>merge|NC_017186|14|3595321-3595412|CRISPRCasFinder
TCACCAGCCTTTGTCGCTCATCGTGCGCTCCTTCCCGGTGGCAGGGGAGTGGGACTCGGTCGCCGGGGTTCACCAGCCCTTGTCGCTCATCG

>NC_017186|14|13|3595321-3595412|CRISPRCasFinder
TCACCAGCCTTTGTCGCTCATCG	TGCGCTCCTTCCCGGTGGCAGGGGAGTGGGACTCGGTCGCCGGGGT
TCACCAGCCCTTGTCGCTCATCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013225180.1|3586884_3587832_-|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|107205
NC_017186.1|WP_013225187.1|3595652_3596843_+|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NC_017186.1|WP_013225193.1|3601069_3601708_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|379115
NC_017186.1|WP_013225183.1|3589013_3590168_+|isovaleryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NC_017186.1|WP_013225185.1|3593173_3593725_-|DUF2231-domain-containing-protein	unknown	unknown	gnl|CDD|370772
NC_017186.1|WP_013225190.1|3599299_3600052_+|ZIP-family-zinc-transporter	unknown	unknown	gnl|CDD|223505
NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase	unknown	unknown	gnl|CDD|185683
NC_017186.1|WP_013225188.1|3596854_3597850_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270450
NC_017186.1|WP_013225189.1|3597932_3598775_+|phytanoyl-CoA-dioxygenase-family-protein	unknown	unknown	gnl|CDD|368580
NC_017186.1|WP_013225182.1|3588212_3588935_-|ArsR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|319973
NC_017186.1|WP_013225195.1|3602651_3603293_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NC_017186.1|WP_013225191.1|3600032_3600350_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NC_017186.1|WP_165476096.1|3598810_3598951_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013225192.1|3600376_3600976_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176871
NC_017186.1|WP_013225186.1|3594101_3595316_+|MFS-transporter	unknown	unknown	gnl|CDD|340863
NC_017186.1|WP_013225184.1|3590543_3592838_-|LuxR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226418
NC_017186.1|WP_013225181.1|3587841_3588216_-|VOC-family-protein	unknown	unknown	gnl|CDD|319924
NC_017186.1|WP_013225194.1|3601709_3602540_-|trypsin-like-serine-protease	unknown	unknown	gnl|CDD|238113

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013225180.1|3586884_3587832_-|pyridoxal-phosphate-dependent-enzyme	gnl|CDD|107205	cd01562, Thr-dehyd, Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.	9.12836e-78
NC_017186.1|WP_013225187.1|3595652_3596843_+|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.69828e-53
NC_017186.1|WP_013225193.1|3601069_3601708_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	1.77771e-12
NC_017186.1|WP_013225183.1|3589013_3590168_+|isovaleryl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	3.39986e-129
NC_017186.1|WP_013225185.1|3593173_3593725_-|DUF2231-domain-containing-protein	gnl|CDD|370772	pfam09990, DUF2231, Predicted membrane protein (DUF2231). This domain, found in various hypothetical bacterial proteins, has no known function.	7.65129e-05
NC_017186.1|WP_013225194.1|3601709_3602540_-|trypsin-like-serine-protease	gnl|CDD|238113	cd00190, Tryp_SPc, Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.	2.75098e-26
NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase	gnl|CDD|185683	cd00413, Glyco_hydrolase_16, glycosyl hydrolase family 16. The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues.	3.03408e-15
NC_017186.1|WP_013225188.1|3596854_3597850_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.41002e-97
NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein	gnl|CDD|270450	cd14747, PBP2_MalE, Maltose-binding protein MalE; possesses type 2 periplasmic binding fold. This group includes the periplasmic maltose-binding component of an ABC transport system from the phytopathogen Xanthomonas citri and its related bacterial proteins. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.3641e-98
NC_017186.1|WP_013225189.1|3597932_3598775_+|phytanoyl-CoA-dioxygenase-family-protein	gnl|CDD|368580	pfam05721, PhyH, Phytanoyl-CoA dioxygenase (PhyH). This family is made up of several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins, ectoine hydroxylases and a number of bacterial deoxygenases. PhyH is a peroxisomal enzyme catalyzing the first step of phytanic acid alpha-oxidation. PhyH deficiency causes Refsum's disease (RD) which is an inherited neurological syndrome biochemically characterized by the accumulation of phytanic acid in plasma and tissues.	3.00078e-08
NC_017186.1|WP_013225182.1|3588212_3588935_-|ArsR-family-transcriptional-regulator	gnl|CDD|319973	cd16345, LMWP_ArsC, Arsenate reductase of the LMWP family. Arsenate reductase plays an important role in the reduction of intracellular arsenate to arsenite, an important step in arsenic detoxification. The reduction involves three different thiolate nucleophiles. In arsenate reductases of the LMWP family, reduction can be coupled with thioredoxin (Trx)/thioredoxin reductase (TrxR) or glutathione (GSH)/glutaredoxin (Grx).	1.75055e-53
NC_017186.1|WP_013225195.1|3602651_3603293_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.57914e-11
NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.76092e-71
NC_017186.1|WP_013225190.1|3599299_3600052_+|ZIP-family-zinc-transporter	gnl|CDD|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	1.73872e-12
NC_017186.1|WP_013225192.1|3600376_3600976_-|SRPBCC-family-protein	gnl|CDD|176871	cd08862, SRPBCC_Smu440-like, Ligand-binding SRPBCC domain of Streptococcus mutans Smu.440 and related proteins. This family includes the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of Streptococcus mutans Smu.440 and related proteins. This domain belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Streptococcus mutans is a dental pathogen, and the leading cause of dental caries. In this pathogen, the gene encoding Smu.440 is in the same operon as the gene encoding SMU.441, a member of the MarR protein family of transcriptional regulators involved in multiple antibiotic resistance. It has been suggested that SMU.440 is involved in polyketide-like antibiotic resistance.	1.12025e-28
NC_017186.1|WP_013225186.1|3594101_3595316_+|MFS-transporter	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.82228e-38
NC_017186.1|WP_013225184.1|3590543_3592838_-|LuxR-family-transcriptional-regulator	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	3.53174e-56
NC_017186.1|WP_013225181.1|3587841_3588216_-|VOC-family-protein	gnl|CDD|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.37358e-14

Protein sequences

>NC_017186.1|WP_013225186.1|3594101_3595316_+|MFS-transporter
MGATRSAFAIRGFRLLWLAGLLSVVGDQLARVALSILVFQRTGSAALSAATYALSMLPALVSGALLSWLADRYPRRRVMVACDVIRAALVGVMAVPAVPLPLMAVLLVLVQLAEAPFSAAQGAVLPELLGSRYEAGQTVQQVTTQLCLVLGFAAAAFVVTAVGAHAALAVDAATFAASGLLIRAGLGRHPPPGSTEREATWWRRIAAGAVAVRRDRTLGTLVWLGWLALFTVVPEGLAVPFAQQAGVGGEWIGVLLAAEPGGAAVGALLLRRVARPVRVRALGVLAVGTAAPLVAFWGRPALGTALALLFVSGLCSAYQVTAGATFVQLSPPRVRGRTLGFARTGMIAGQGLGIVAGGVLAQLVGPAAAIAWAGTAGALVALAAAAAWARRRPDAVSAALPAEA
>NC_017186.1|WP_013225185.1|3593173_3593725_-|DUF2231-domain-containing-protein
MQKADRVETPAAPHRVLMAVEDADVLDVPATALAYRLRGAATSAPGRLLRGRWLGHPLHPLAVTVPIGAWLCSALFDLLPGQEEAARRLVATGLLAAPAAVLLGLFDYADLDERQRRVGLAHAAGNAVAIALFGASYTARTRGRVARGRVLGALGLAVTSAGGALGGHLAYAQGAGFFRWQSR
>NC_017186.1|WP_013225184.1|3590543_3592838_-|LuxR-family-transcriptional-regulator
MGARSRRSAGNLPAELTSFVGRRHELGEAKRLLATARLVTLTGAGGVGKTRLALRVAADVRRAFPDGVWLVELADVGDPHLVPNTVATAFGLRVTSDQAAGLAEYLEDKQLLLVLDNCEHVADECATLVAKLLAVSAGLRVLATSRHTLHVEGEHLLHVEPLPVPGDEDAGGGPVEAVTLFADRAAAVSPGFELTPDNRATVSRICRRLEGIPLAIELAAVRVRVLAVDQVLERLDDRLGLLTSRPAAVQPRRRTLEAAIDWSFELCTPAEQRLWAQASVFPGGFDLDAAEGVCVPAADGGSALDVVAGLVDKSVLSRQNGTFGRHAWYRMLETVREYGGARLAAGGDEAGVRARQAGYYADLARRYRAEGFGPRQSEWLGRLRREHANLRAVLEHCLSGPGQASQALDIAASLWNFWYGGGLVPEGCGYLRRGLELCGERTLVRARGLYAMAFLAIQTGAPHAQLLAELDELAEELGDERLRAGHAECAGMATFFTGDLSGGAELLERALAGYRTAGDPLLVFDTLILLAAARFFLGDPRGAAAAEEALALTDRHQARWSRGYALWAVAIHRWRAGEPRQATDLLHEAVALRLPDRTLLAFLVEALAWCHSAEGEHDRVARLLGGAGAVWRLSGARVGEMSPYQAVDEQCAALARKALGEDAFAAAFAEAAGSGLDDVVRYALRERPATRAAGKAAEPGGLTRRQREIAELVARGMSNKEIAAALVLSGRTVEGHVENILVKLGLTSRTQVASWLAGQPGRPA
>NC_017186.1|WP_013225183.1|3589013_3590168_+|isovaleryl-CoA-dehydrogenase
MAGLTEEEAAIVAVVRDFVDHDVRPVVRELDHTDTYPEALIERMKELGVFGLAVPEAWGGTPVSARCYAEVTEELACGWMSLAGAMGGHTVVAKLIVTYGTREQQERYLPRMATGEVRATMALTEPGGGSDLQALRTTARRAGESYVVDGAKTWITNARRSQLVALLCKTDPHAEPAHAGISILLAEKGAGFHVSRDLPKLGYKGVESCELSFSDFRVPVGALLGGEEGRGFAQMMRGLEIGRIQVAARALGVGRAALADSLRYAQERETFGKPIWQHQSVGNLLADMATKLEAARQLVHHAARRYDSGARADLEAGMAKLFASETAMEIALNAVRVHGGYGYSTEFDVERYFRDAPLMIVGEGTNEIQRTVITRQLIRRHRLG
>NC_017186.1|WP_013225182.1|3588212_3588935_-|ArsR-family-transcriptional-regulator
MASEPPAFVRLAAHPLRWALLTALAGGDLRVRELVERVGEPQNLVSYHLRLLRGGGLVTAARSSFDGRDSYYHLDLDRCAGALAEAGAALHPTLDPAPRPQVPPPRPVAVLFLCTGNSARSPIAEALLRRRAAGAVTVTSAGSHPKAALHPGAIRALEEFGIDVRGQRPRHLDTVAGQRFDHVITVCDKVREVCPEFPHHPRRRHWSIPEPGSFPETAAELDTRVRHLLPELVPGKEVRP
>NC_017186.1|WP_013225181.1|3587841_3588216_-|VOC-family-protein
MSEQYAGVRYVVDDVQAALDFYTTHLGFTVRMSAAPAFADVVRGPLRLLLSGPASSGARATPADASAAGRNRIHLVLDDLDAEITRLTDAGVAFRTEVVSGPGGRQILLADPAGNLVELFQPAH
>NC_017186.1|WP_013225180.1|3586884_3587832_-|pyridoxal-phosphate-dependent-enzyme
MPEMRLDLARIRAAREVIDPVFLDTPLYRCEALEPVLGCAVSIKLETANPVRSFKGRGTEVVASRLAGPVVCASAGNLGQALAWSGRGRGLDVTVVASRHATAAKLERIRALGARLELVDGDHELARERAATIARRDGSRLVEDSLDLETCEGAATIGLELVDATPTFDAVLLALGGGALATGVGHVVRSGAPGTEVICVQPAGAPAMTRSWHARRVVTTGPTATIADGVAGRRPIPEVLADLLVVADNAVLVTEASIITGMRLLLEHAGLVAEPSAALGIAAILEDRDRFAGRHVVTVVCGGNVDLSAYRDWVR
>NC_017186.1|WP_013225179.1|3585569_3586748_-|glycosyl-hydrolase
MSRSSIRTTTAALTSLATAATAALVLSGGADASPASAAAGCGVLFDDFHYSSPTDGAFGGAGWTTRNDVGSPGVPGARWLTSNISFPAVNGERVAQLTATTDGSAAGTTHAELYQNQLRFFEGTYASRVRFTDAPDSGPDGDHVNETYFTISPLRYDRDPLYSELDFSEYLPNGGWGGSTANYQTSWYTYWNNPTWDGLRTSTAQNRSFAGWHDVVTQVSGGHVKYYIDGVLTADHTTDAQGDPVYPRTPMSINYNMWFIDTAGHTSGTSAYTEQVDWTYYAGNQVVSPADAVAQAGQYRSAGTSHVDSVNGCSTPTTPPATTTPTTTPTTPTTPTTPSQPANCSSAAEWDWGTMYLEGQRVKHNAHLWQANWWTQGSEPGLTAQWRDLGHC
>NC_017186.1|WP_013225178.1|3584277_3585594_-|extracellular-solute-binding-protein
MARPRPLLTTQELPVRRPVLAAVLAVAAVTATACGTDTPAPAARGGELTVWLMNGDLSDKATAAITTAFEKATGAKVTVQIQEWDNINTKISTALAQDSTPDVIEIGNTDVPLFAANGALTDLNPHRDELAAGQTWLPGLAGPATVDGHLYGAPLFAGNRAVIYDKQVWADAGVTAPPKTLPELTAALDKIKAKHPAPDYSAFHFPGRYWFGALQFVWDAGGQLATQRAGKWAGALESPEALKGLQAWKDFQNAYSSPASRNVDTKAPDQAAIFSAGGAAAILDTSVNTVLKNKPELKDRLGTFPFPSGTPGKTQPVFLGGSDVVVAAKSRNSDLALAYLKAATDPAVQRDAIAGIDGWTPISTELIDRITPALPPLNAAFATAAKTSVATPAAPGWATIESDKSINTFFADIATGRRPIADAAKEFDAHLTEALGAR
>NC_017186.1|WP_013225177.1|3583283_3584207_-|sugar-ABC-transporter-permease
MLLEKAPTRERTPRVSLLPYGLLLPAAALLGLVLGYPLVRLVVISLQEYGLRSLFTGTTRFAGGDNYAAVLADPQLLPVLGRSLGFCAALVAGTLVIASGVALLLQRLGRRMRTAVTLSLIAAWALPNVASTLVWQWLFQPGYGVVNWLLTRLGFGDLTQHDWTTSPASAFTLVWLLVVWQSVPFAALTLHAGLSQIPRSYYEAAALDGAGPWRVHRTITVPFLQPILGLVTILSVIWDFTVFNQIWILTQGGPGGGTTTLGIWTFTRAFSRNDFGQGAAIAVVSVALLAGLTAVYVRRLVRSGEDL
>NC_017186.1|WP_013225187.1|3595652_3596843_+|GGDEF-domain-containing-protein
MRFLVLGVDLLALGVLVLAARAAPTPGQWVTAAWLAAAALPHLHASHVIERRRRDRAGAPYVDLCSVWIFAGVIVLPLVLELVLVAVIYAHRWVLVNRFDAVRPPHRTVYTAATLALAAAAAAAVLQSSGVHQHLAGGARPGWADLAAVVAAAAVQWAVNTGLVGTVIAWTVTVEHPRRLIGSASDNLLEVSQLALGVFVALALLWWPPAALLMIIPTFALHQCVQLDQLKLAARTDQRTGLLNAIAWHEQAEHALERTRGRIGVLMIDLDWFKRINDTHGHPVGDDVLAEVATVLTRTVRRGDTVGRYGGEEFAVLLPDVDEAEVRAIAERIRLRIRGLRITAPTGEAVTLSATIGAALDPAEPGAGLDEMIRAADDALYAGKKAGRDRVAVAGW
>NC_017186.1|WP_013225188.1|3596854_3597850_-|LacI-family-DNA-binding-transcriptional-regulator
MNPKLRDVAEHAGVSVRTVSNVVNGFRYVAPATRERVQASIDALGYRPNLAARTLRRGRTGLVALVIPEIDSPYFAELAARTVRIAGARGLTVLIDQTDGDAEREKELLHGRRSQLVDGVLFSPWAVAPAELAARTDTVPLVLLGEHDGTAGVDHVAIDNVAAAREATRHLLASGRRRVAALGIQPRSLNATARQRLAGYRQALAEAGLPAEPELEVPVRRLHRADGHRAMLGLLELSRPPDAVFCFTDELALGAVRAAADRGVAVPESVALVGFDDIEDGRYSVPALTTVSPDKDRIAELALDRLARQAADPEPPRSIVAPHHLEVRESS
>NC_017186.1|WP_013225189.1|3597932_3598775_+|phytanoyl-CoA-dioxygenase-family-protein
MTAHQTAPAPLSAADLAALTERLESDGIIGLPGAFPRAWVRQLGEDIDTAFAEARARPGGAVGRGPNRFYVEIHPEQLRGFAELAGHPWITAVAEAVLGPAYRIVEVGFDVPLEGAVDQPWHRDFPMPAETAREGRLTSLAVNVTAVDTEPDMGPFEIAPGTHRDDGCAFDHGMFPPREAWPRYRELATRKFPRMGDISIRSALTVHRGTANHSAKARPVLVLGLDAPGAGNDARHDTAVTREFWAALPESVRAHLHCPVVDVLRPITQKHTIEGLVMGA
>NC_017186.1|WP_165476096.1|3598810_3598951_+|hypothetical-protein
MADAGITEMTGRAGVVAALRRVLLAFGVGGALACLGWMALWLAMHV
>NC_017186.1|WP_013225190.1|3599299_3600052_+|ZIP-family-zinc-transporter
MPQWVEAGLWGLVGGVALVLGAAVAWWVRVPRRVVAGIMAFGAGVLISALAFDLVDEAQRSGGLVPTAGGFLGGATVYVLINVLLARRGARHRKRSGDQQPSEQDTAGSGAAIAVGALLDGIPESVVLGVSLLGGGGIGVTVLAAVFISNVPEGLSSAAGMKTAGRNARYVFGVWSGIAVASGLAALVGNLLLRSASPATVAAITAVAAGAILAMIADTMIPEAFERTELYTGLLATIGFLTAFVIEHAG
>NC_017186.1|WP_013225191.1|3600032_3600350_-|hypothetical-protein
MTVTAPPRTSKAVLVAAWSVPVLVAGQFALLSGVPIAVVLIGSLRRRANRRWAAALAAVYATALTAWLAGPGSAPSLSKFLSPVATALFTAAGVVVAAALSRRAR
>NC_017186.1|WP_013225192.1|3600376_3600976_-|SRPBCC-family-protein
MIGTRLRSALLALSVAAGLAGTATSAEATPAGALSCRGVGIDPATQLHYRTETFIKAPAAAVWELHTDVARWPAWQPAVTSAQRLDAGPLRPGSRFRWTTPAPPTPTTPATTLVITSTVGQLQPGRCVRWTGPAIGDGLRIDRGVHVWTFTPVRGGVLVRTEESWTGEQIEADPATAIRYLAPGLDAWLAALKTTAEAR
>NC_017186.1|WP_013225193.1|3601069_3601708_+|TetR/AcrR-family-transcriptional-regulator
MTSESPRERYRAQVREEIKRHAWEQIAAAGVPALSLNAIAKQVGMSGPALYRYFASRDELITALIRDAYRSLADTVRAARDAGAGLPGLAGTIRDWARSDPQRYFLVYGTPVPGYHAPDDTTAISFEVMAVLIEACAEETGEEPPTPFDAHLETHREWAGGHPAPAAALHRALSFWTRLHGVLSLELAGHFAGMKFDPDLFLAEELAALRAR
>NC_017186.1|WP_013225194.1|3601709_3602540_-|trypsin-like-serine-protease
MAVAVLTGAGLAFAHAVTGVTVAGPILAAAAGGHSLPDTAAAAPAPVPVTTSARPAPNPTLPFNAKLTSDDIPVPGGGVRNGACSGALVAPQWIVTAGHCFHDLKDARIGGRPPYTMTVTVGRLKDTDPGGYTTEVVDVRQSPVNDLAVAKLGRPIDDIVPVALATSRPSVGKQLQFAGWGSHSATVLGPSDHLKRGRFTVSGIGQATLEAQPVGTRTVENGPCPEDSGGPFFVSDDDRTGTLVAIVNTGPPCPQPGAETIARVDVVADWIREQIG
>NC_017186.1|WP_013225195.1|3602651_3603293_-|TetR/AcrR-family-transcriptional-regulator
MASARETNPEAPRPGGRPRDAALDEAIILATRERLVRDGYSLMTIGDIAADAGVSRPTLYRRWRTKFDLVVDALDYGFRKQRDSSPADLTGMAPREAFTEAVRRLDPAYFNPDAMVLMGNFAGEAIRTPELLGILREHAVEPRVTLVENVLSQLQESGDVAGDIDKHTIATLCFGSYFAAFYRGESRDEIPEAVVSVLWPAIAAKKPARRRRG

Crispr_ID: NC_017186_16

• CRISPR_ID: NC_017186_16
• CRISPR_location: 5356387-5356467
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_16

Consensus_repeat	Method
GCCCGCAACACCGGAAGCGGCGG	CRISPRCasFinder

spacers of NC_017186_16

>16.1|5356410|34|NC_017186|CRISPRCasFinder
CTCCGACGCAACCGGGCGCCCCGATGTCTCGACA

CRISPR arrays and Neighbor proteins around NC_017186_16

CRISPR arrays

The CRISPR arrays of NC_017186_16

>merge|NC_017186|16|5356387-5356467|CRISPRCasFinder
GCCCGCAACACCGGAAGCGGCGGCTCCGACGCAACCGGGCGCCCCGATGTCTCGACAGCCCGCAGCACCGGAAGCGGCGGT

>NC_017186|16|15|5356387-5356467|CRISPRCasFinder
GCCCGCAACACCGGAAGCGGCGG	CTCCGACGCAACCGGGCGCCCCGATGTCTCGACA
GCCCGCAGCACCGGAAGCGGCGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein	unknown	unknown	gnl|CDD|223540
NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein	unknown	unknown	gnl|CDD|269824
NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein	unknown	unknown	gnl|CDD|274305
NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein	unknown	unknown	gnl|CDD|274050
NC_017186.1|WP_003098516.1|5357967_5358126_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226671.1|5358122_5358572_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein	unknown	unknown	gnl|CDD|377431
NC_017186.1|WP_013226678.1|5368207_5369029_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein	unknown	unknown	gnl|CDD|226028
NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|212030
NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein	unknown	unknown	gnl|CDD|379338
NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein	unknown	unknown	gnl|CDD|224387
NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein	unknown	unknown	gnl|CDD|273730
NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein	unknown	unknown	gnl|CDD|379449

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	5.49739e-27
NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein	gnl|CDD|269824	cd14739, PAAR_3, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	1.82721e-26
NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.83282e-06
NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein	gnl|CDD|274305	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB. Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	5.17064e-29
NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.00618e-70
NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.067e-22
NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein	gnl|CDD|274050	TIGR02242, putative_secreted_protein, phage tail protein domain. This model describes a region of sequence similarity shared by a number of uncharacterized proteins in bacterial genomes, including Geobacter sulfurreducens PCA, Mesorhizobium loti, Streptomyces coelicolor A3(2), Gloeobacter violaceus PCC 7421, and Myxococcus xanthus. In all cases, the genomic region resembles a phage tail region, based on tentative identifications of neighboring genes. A region of this domain resembles a region of TIGR01634, another phage tail protein model. [Mobile and extrachromosomal element functions, Prophage functions].	2.29002e-24
NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein	gnl|CDD|377431	pfam04965, GPW_gp25, Gene 25-like lysozyme. This family includes the phage protein Gene 25 from T4 which is a structural component of the outer wedge of the baseplate that has acidic lysozyme activity. The family also includes relatives from bacteria that are also presumably lysozymes.	1.3903e-34
NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	1.1604e-06
NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	1.46325e-38
NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	2.80163e-33
NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein	gnl|CDD|226028	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only].	1.80502e-61
NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	1.22178e-07
NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein	gnl|CDD|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	5.72344e-33
NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein	gnl|CDD|224387	COG1470, COG1470, Predicted membrane protein [Function unknown].	0.00025614
NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein	gnl|CDD|273730	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein. This model represents the Vgr family of proteins, associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region, VGXXXXXX, found in the Vgr of Rhs classes G and E.	3.59266e-20
NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein	gnl|CDD|379449	pfam14065, DUF4255, Protein of unknown function (DUF4255). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 320 amino acids in length.	9.23209e-48

Protein sequences

>NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein
MPDTEEAVAVCYVVKLDDKNLGNLGAFSSCDGLGCEFVMEQREEGGNNGMVWQLPTRIKYSNIKLSRPVTEASSQITKWFASLAGGIERKTATIEARTLEGKVIASWALEGVVPVRWSGPQLSPDSPKVATETLELAHHGFLSPAKKG
>NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein
MPSPVTFTSAGSQSTAAYSSGAPSNLQRAVLKVHKPPQSGGTGQPPGDWMFDIEFQFNPKEFSVSKNAKWGRDAQPNAKKSAPPQFKGSDPAKLSLEMFIDATDKMNDAVVKKVEQLFTCCVATEDSRQHKKPSPPWVIFKWGGMTGFPAYVASVTAKYTLFTPAGTPVRAICTVNLEEISGELGGQNPTSGALAARDTHVLVAGDSLPSVAFRAYGDAGRWREIADANDIDDPMRLRPGTRLLVPALEELDG
>NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein
MANETFTNTLVVEVEGTALPDDVRVMLGYAYVDDSRNLPDTFVLRFRDPGAVVLEKGKFKVGAKIKLKVQTSDPEGPQDLLSGEVTAVAVDLDPHGTFTEVRGYDHAHRLFRGRRVAAYPNMTIADVVRKVARRANLPAGKIDDVKGVGGRPNAQLSQDNVSDWEFLSRLADVVGAQIAVRDGKLNFELPEKPSGAPSPTTKATADPLVLEAHGTLLSLRASVTAAEQVPEVRVNGWDYENKQPITATATPKNAGTDVPGVDPVALAGKFASPPFLDAAAPRRTQGEADATAKALADRFGSACTELDGVAKGNPKLRAGAAVTLTGVGQPFSGKYTLTSTRHLFNDEVGYTTEFAVSGRQERSLYGLVAGGAKPSSWPGVVPAQVTDLKDPAKLGRVKLTFPWLDKEFTSTWARTVQPGAGKDRGALVLPEVGDEVLVGFEHGDFEAPYVLGGLYNSKDTAPSKFTKAVVDGNSGEVALRGFVSRKGHKLEFAEDDGIILSSGDAKFVVKIDQKNQVIEVTSGKSVTVKAQNGVSIDAGSGPLELKGQKVSVKSQTDASIEASSQLKLNGTAGVKVEGATVSVAGQGQTELTASGVVTVRGSVVKIN
>NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein
MPPAARVGDPTGHPGVIAGPGVPTVLIGGLPAANVGTLHTCSFPPPAVHPPTPIAPPGCPTVLIGGMPAARMGDMATCGAPIVMGCPTVLIGG
>NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein
MTGKDFLGRGLAFPLHTDATGSIALVGGEREVVESIRLILATSPGERPMRPEFGCAVHDLVFAPADAATAGQIAYEVRTSLERWEPRITLDDVVVSFDQADRGTLLIDIRYRLRGTNDPRNLVFPFYVIPPHESAALDSQADGA
>NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein
MRTGIPGLPSPHPIGEQLPSVYAEDRFVQGFTGALDEVLAPVISTLDNFSGYLDPGVAPADFVGWLAHWVALGVDESWHPDQLRQLVTRSVELHRWRGTRRGLTEHVRLLTGGAVEVTDSGGVVADPQPGAPLPDPGPPWVQVRVRVPDPARVDVRRLTATVVDAVPAHVRVTVEVLEG
>NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein
MRANRAVAGIAVVAVLGGWALSGALAPTEAQAPAPVASPYRVGYVSEATTGLYQATGEGAEPALPRAVGGVDSDASAGTGGIVWVSHRAAAAGGAERDGELWFLRDGAPTALQLTNDDAVDLHPALSPDGRTVAFASERTGSRKLFVIGVDGRGLRQVTSGPATDDSPSWSPDGTRLAFSSTRDDPAGDIYTVGVDGGTPARLTTDPAADTQPAWGPARIAFTTTRFHPAGDVVLMAEAGGAVTRAVPDPGDSSEPAWSPDGRLAFTTRAKDPSGDVRQIVGETVTDISALKDIGETEPTFRSDGRPVFTELRASGTTDIWSADAAGGDRRDLTNRPGADEFDPAFSADGSQLAYTQGGRGDSVATEIIVANADGSGPRPLTGPTDGTKRERHPAWSPDATAIAFTVTVGGGESSRDVVRIARVADGRILGEIPIPPYLSGNDSQPVWSADGTKVTLTRAASRIAPPPPGRVDPSVVDIPVGQGSSAAIEKKVPTDKVPAKPDIVLLMDQTSSMGDALAAMKASLTQVMTTISTAQPDAQYAAVAFGDRDDVADKNNPNGRLFQVQRDLTKDQAAITKAFENITIGGGIDTPEDWIYALDRLATGAVTFRPDSSRIIVLVGDAPSHDPSGDHLHHDQGVTLTQAIEHLKAQGIRVVGVSAAGSGGGLDSDPAHQATQVTTATDGVLASTDPANISAVITEKIGDLRVKVQPVPFCDPGLTLTFTPEGTQQVPGGTTANFTEFAAVAPTAPLGAFLHCRVEFRLAGESTVRAGYTEDVTVRVKDPRLPLITLHDKTVTGTAPTVVEYPVTAIDADRETRLTPFCSPSSGSLFPVGATTVTCTATGRGGTATESAVVSVDPGGEYRQELWQVALAAGPDSVVPGTQRNLSPSFGTPCGVGRQGSADVSPDGAALVFQNDRSQLCVAPADGGRARVLVQSGDEGESLNDPAWSPDGTLVAYDSAFSESVPSILIVPSAGGTPRPLIDGPGGAGQPAFQRVADVGVTATAVPAAIPFSGLTTFEFVVTNHGVAAAPGVGLFVRLTAGLRPQAPITSAGTCTPDLVCALGTLAPGAQARVRFSATGAEPGPQAATGTVTTAGQDADARDNSATAVVTVGEKPVPPVTQGSLSVGLAVSAVPLFVGGDDVVLTFLVHNGSGAPMPDVRLVTQLPPQLPATSVSPGCAPGGGSCALGTLAPGQTVEIRIALAAKAAADTPVAGTVSTSGPDTDPRDNTASARVVIRQPVVTVDPGVGPLGSVPRVTGTDFPPGATVGLAWSAGISETPGLATVGVDGKFEAQFLIFHHDLTGPRTVSVTSVSGPKFGTAQSNPILVVLRTEQPPFITRG
>NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein
MGATATLSEAGLVAEPGQETSCTVTVRNAGQVVDQFAIDVVGDASGWATAEPATVNLMPGETGTVTVRFAPPRSSDVPAGTIPFGVRVFSSEDPAGSVVEEGTVELGAFTEVTAEIVPAKVEGSSKADFEVAVDNRGNRPVAVELSPLDPEDELDFRLERDRAELAPGTAAFIRMRTRPRKRFLRGQPVRHRFQVFVVADGAEPLKTEGTMVQRQLLPKWLLPVLAALLILLLALVTLWFTVLRPAVKSAAREAAEEQNHEIVKAAQDAGAGADQAKKNADQAKQNSEQAMKAVGLTPPGDASAAPGTGAGPGTPPPTRVSNAAADGTPTDFRVAADAKTDSNVNRFAEFPYTLPDATKTLVITDLILQNPRGDAGTLRLLRDSGGTKTVLLEVGLSNFRDLDHHWLQAWRFQPGDKIVLAVSCQNPADRGHCTPSVSFSGRVE
>NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor
MITDQVPVLLHATDTITHAGVTAALRSRPEIRFADEDSGEPAVVLVIVERLNEQARQLLRSLQCAGHTGVVLVAGEVEDSELLDVVGNGVSAIIRRADATPDTLVRLVKAAAVGEGALPPDLLGRLLSRVSRLQRDVLRPNGWDLAGMSQRETRVLRLVADGFETKEIADQLSYSERTVKSILHDITNRFQLRNRAHAVAFAMREGLI
>NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor
MFGSLRVLVVDDHPVFRAALCAMLDATDGMEVAGEAADGLTAVTDAGRLEPDVVLMDLNLPDLDGIEATRRIVSASPHTGVLMLTMFENEAAVFAAMRAGARGYLLKGARNEQIIRAVRVIGDGEAIFSPAIATRVLSLLGTATPRDESFPRLTLREQEILRLVARGMGNASIAEELVLSQKTVRNHVSHIFRKLRVTDRSQAIAKAKEAGIARSE
>NC_017186.1|WP_003098516.1|5357967_5358126_-|hypothetical-protein
MTYAADRLHEEVAYVAYHLHWSLDDILDLEHPDRLTYVAEIARINTRMSQGR
>NC_017186.1|WP_013226671.1|5358122_5358572_-|hypothetical-protein
MRRVMASAPVEEAPAAPAGEPRAERPKLRTEFAFELPRGYVDDEGKVHHSGVMRLATARDELIPLRDDRVRENSAFLTVVLLARVVTRIGDITDVHAGVIENLFASDLAFLQDMYRRVNSEGHTRAGVACPECGHSFVVDVAGGRLGES
>NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein
MALPDLDKAVGHSFGLEIDGVQIKQISEVSGLKMEQDVIELKQNTADGKYVIKKLPGRPKAGEVTLTRGLTEDNSFEKWVKDAHFGKMATARKGGAIIVYDYEGTALKRYKLTNAWPKSLEIGSLKAGDTSVLTEKLVITYEQMEVE
>NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein
MPTYLTPGVYVEEIEAGARPIEGVGTAVAAFVGFAADGPFNTPTLVSNWGQFTQTFGDFIEGCYLAQSVYGYFLNGGSNCYIVRIGGSRAQNNGAAPKQIEARQAVLGGYRFVAKELPEGKQGGEITVEVAEPTGDNPAEDRFTVLVKQDGKVVETHNVTTKRTKENVVTAVREKSSLITIEEVATGGAVTKPDKGTAVLSAPPKDPEAPPVPRRVAANDYVGDVADRTGFGGLEAIDEITMVAAPDLMAAYQRDLIDLDTVKAVQLAMIAHCELMGDRMAIIDPPPALNPQEIRSWRMDAAGYDSKYAALYYPWVQVLDPASGTNAFIPPSGHMAGVWARTDATRGVHKAPANEVVRGALALETHLTKAEQELLNPIGVNCVRSFSGKGIRVWGARTLSSDPAWRYLNVRRLFNYLEESILGGTQWVVFEPNDDALWARIRRTISAFLVMEWRKGALFGLTPDEAFFVKCDRETNPAEGIDLGQVICEVGIAPVKPAEFVIFRLAQMSGGTSLVNE
>NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein
MLRLQASAGNAAVSGLVALQRQGCPAPPVAPPGVTPASDPKFQSLKKDVGGQAKTAKAHPPAGAEVKKAQDAAVAPPDDKDAQAKAAQADKMAAAKPAGFDKAAFIAAVNAAIAKQAPKNLDEADKFATSGKADQVKAEVLGKVTSGKDASAKDVTDRTKEPPDPGRAVEKPVTPLPEPPAAPVLAPPDARKATPDKAPPEQTDLRAGQCETQGAMAEAGVTDQQLAESNEPEFTGALAAKREGEQHTASAPAAVRESEAGQLAAVTGAAQASGQAAMAGMTGARSSSAQRGQAAKSATKSKDEQDRARITGEIKAIFDETKTKVEGVLGALDDQVAKKFEAGEAQAKAAFTADHQARMKRFKDERYDGITGAARWAYDLFADLPAEANNLFLEAKKVYESKMQGVIGDIADFVGQKLGEAKQLIADGRARVQQKVASQSPALRKIAGEAAKEFGGQFDDLEKSVDEKQDALVEDLAQKYGEARNAVDEEIKTLQAENKGLWSKAKEAVGGAIETILKLKDMLLGVLSRAANAVGLIIAKPIEFLGNLVNAVKTGVMNFGANIVEHLKEGLKGWLLGNLASAGIEIPEALDAKGILKMVLSLLGLTWASVRARILRFIPEPVLAKLEQTLDVVKILLTEGVPGLWRWIVAKLGDLKEMVLGQIKEFVIEKIVKAGITWIISMLNPAAAFIKACKAIYDIVMFFVDKAAQIKEFVDSVLDSVESIARGGSGAVAGLIERTLAKALPMVLGFLASLLGLGGISEKIKSVLEKVQAPVGKVIDSVVGTIVKAGKKVWSKFKGKKGSGVPDPRSAGQKQQALAQAKQAADAEMRKPNATQHTVEAALPKIKDTYQLTTIALVPTSNGKFKTHLEVNPTDDTGELPLGPMAPVDEAKVYLGKRFVVKATNRVAKVTDVRPDGWVTLQYELERNAGGRSKSSEGRPAFPVLKFLANTPNGGPELAPAEGGASQTQYTIDGKTLRPEYHDVRAVFYGGSHKYSGHDAAKIAAVMRPDGRTFTCPGVPFLGIAPHVAARVKPNNADNYALDHRKSVAGHWNTQGREKSQTDRSQFYADPGNLEVLCGSCNSKKGSKDADTGAAERYRKDVEIPGFTGPDGKE
>NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein
MRGHSHENDLEPALRPKGDRIERDDHDLLGRAAAAGRTDVLGPAGMLGLQRAAGNAGTASLVEEDRSPVHDVVGSGGGTPLDTSTRVDMESRFGHDFGDVRVHTDGAAHDSAKSVNAQAYTVGSNIVFQRDKYDPSSDSGKHMLAHELTHVVQQRSGPVDGTDAGGGVKVSDPSDRFEREAVANADRLMSSPAPAGPAVQRCEDGGHAAHSEDSAAVQREEAPEAEEGEEKMAQTFVQREEEAEEEA
>NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein
MSLEYLFERLARLEQRIRDAVDSRRAADPNPDDPFRGLYLSNETIDALLEGLREPFTPFTDSVPDGRLRPLAERAGLTGVDVELLLVALAPDLDSRFEQFYGYLNDDVTRRRASAGLALRLCGIPEASAAGRARLDADSPLVTCGLLTVGEDERPFLSRTLRVPDRVVNHLLGDDRLAPELAGCAHLGTELVEVPGRERLARAIRGRVGLVYLKEQPGGGAEELGVGALAAAGYPALVVDAERWQAEPGHAELTASLRREALLRGAGIVLGPVEDPRLEALAHPAIPLVAHGTGAWDPRWSATPPLQLDALPLSAADRAELWRSRLEGRLAPGVDPGEETAHFVLGPGQIARAAKAASVTALADDGLVRTAHVRAGARSQNAAGLQRLARRIEPVVGWADLVLPAGVLSLLDELAARARYRDQVLDDWRMRPGGGRGRGVTGLFAGDSGTGKTMSAEVIASSLGLDLYTVNLATVVDKYVGETEKNLERIFTEASGVNGVLLFDEADAIFGKRSEVRDAHDRYANIESAYLLQRMETFDGIAVLATNLRANLDEAFTRRLDVIVDFPLPDVELRHRLWDRCLGVRMPRGADLDLGFLAEAFELAGGHIRSAAVTGAYLAAEAGRPVAMSDLVGAVAREYRKLGRLCLDREFGPYLAMVTDG
>NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein
MIHEVDEALRRLVKDEALRGSEVDVAFDAPTKDWAARRNAPTVNIYLYDVREDMRRRSRGLLNEYDQRGEVAARHLPPKHVKLSYLVTAWTQRPEDEHRVLSDLLLGLLRHEAVPAEVLSGSLAEMGLPVPMTVALPPPEDRAFADVWTALGGELKPSLDVVVSAPIHSGRVYPAGPPAKEGLKLDTGDGELLGHHVSATGAVEGQRRVAMARTHRKPR
>NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase
MLVENVVVAAEYRRSGVGAALVEAAFAIARQARCYKVLLAVPVRPGSRPERFHARSEPGPRGADPARSASAVTGNVSPGRSRSRCPRRGRPRRCRGPWRRPPP
>NC_017186.1|WP_013226678.1|5368207_5369029_-|hypothetical-protein
MSTLRRLAVAGAFALPLSLVIAGPATAHPLGWPNDSWSAESSSSWAGIGGAGTTDTDEGSTWWGHHWSDSDAAVAGIGGAYVTHNGESGDDGWNHAWHHPAHNGWQDGDDDDCDYDAGDQHHYVYGDNDDAPDVVDHHHHVMSHPDPVNQEPVGYVAHPVYDADDDGADDVGYYAEQHSAGVDGATSAHVVSHAGEHHATYDAEKYTAGPHGASSEGAHALAVPDYAGYHAWYTAAGVGGAAAHSVTAVADATDHDNVWADHDADSDYDYDRG

Crispr_ID: NC_017186_17

• CRISPR_ID: NC_017186_17
• CRISPR_location: 5356741-5356829
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_17

Consensus_repeat	Method
GCCCGCAACACCGGAAGCGGCGG	CRISPRCasFinder

spacers of NC_017186_17

>17.1|5356764|43|NC_017186|CRISPRCasFinder
CCCGTGCCCCGCTGGTTCCACCGTCAGCGCCGAAGTTTCGACC

CRISPR arrays and Neighbor proteins around NC_017186_17

CRISPR arrays

The CRISPR arrays of NC_017186_17

>merge|NC_017186|17|5356741-5356829|CRISPRCasFinder
GCTCGCGACACCGGCAGCGACGGCCCGTGCCCCGCTGGTTCCACCGTCAGCGCCGAAGTTTCGACCGCCCGCGCCACCGGCAGCAACGG

>NC_017186|17|16|5356741-5356829|CRISPRCasFinder
GCTCGCGACACCGGCAGCGACGG	CCCGTGCCCCGCTGGTTCCACCGTCAGCGCCGAAGTTTCGACC
GCCCGCGCCACCGGCAGCAACGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein	unknown	unknown	gnl|CDD|223540
NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein	unknown	unknown	gnl|CDD|269824
NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein	unknown	unknown	gnl|CDD|274305
NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein	unknown	unknown	gnl|CDD|274050
NC_017186.1|WP_003098516.1|5357967_5358126_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226671.1|5358122_5358572_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein	unknown	unknown	gnl|CDD|377431
NC_017186.1|WP_013226678.1|5368207_5369029_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein	unknown	unknown	gnl|CDD|226028
NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|212030
NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein	unknown	unknown	gnl|CDD|379338
NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein	unknown	unknown	gnl|CDD|224387
NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein	unknown	unknown	gnl|CDD|273730
NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein	unknown	unknown	gnl|CDD|379449

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	5.49739e-27
NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein	gnl|CDD|269824	cd14739, PAAR_3, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	1.82721e-26
NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.83282e-06
NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein	gnl|CDD|274305	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB. Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	5.17064e-29
NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.00618e-70
NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.067e-22
NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein	gnl|CDD|274050	TIGR02242, putative_secreted_protein, phage tail protein domain. This model describes a region of sequence similarity shared by a number of uncharacterized proteins in bacterial genomes, including Geobacter sulfurreducens PCA, Mesorhizobium loti, Streptomyces coelicolor A3(2), Gloeobacter violaceus PCC 7421, and Myxococcus xanthus. In all cases, the genomic region resembles a phage tail region, based on tentative identifications of neighboring genes. A region of this domain resembles a region of TIGR01634, another phage tail protein model. [Mobile and extrachromosomal element functions, Prophage functions].	2.29002e-24
NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein	gnl|CDD|377431	pfam04965, GPW_gp25, Gene 25-like lysozyme. This family includes the phage protein Gene 25 from T4 which is a structural component of the outer wedge of the baseplate that has acidic lysozyme activity. The family also includes relatives from bacteria that are also presumably lysozymes.	1.3903e-34
NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	1.1604e-06
NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	1.46325e-38
NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	2.80163e-33
NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein	gnl|CDD|226028	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only].	1.80502e-61
NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	1.22178e-07
NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein	gnl|CDD|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	5.72344e-33
NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein	gnl|CDD|224387	COG1470, COG1470, Predicted membrane protein [Function unknown].	0.00025614
NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein	gnl|CDD|273730	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein. This model represents the Vgr family of proteins, associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region, VGXXXXXX, found in the Vgr of Rhs classes G and E.	3.59266e-20
NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein	gnl|CDD|379449	pfam14065, DUF4255, Protein of unknown function (DUF4255). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 320 amino acids in length.	9.23209e-48

Protein sequences

>NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein
MPDTEEAVAVCYVVKLDDKNLGNLGAFSSCDGLGCEFVMEQREEGGNNGMVWQLPTRIKYSNIKLSRPVTEASSQITKWFASLAGGIERKTATIEARTLEGKVIASWALEGVVPVRWSGPQLSPDSPKVATETLELAHHGFLSPAKKG
>NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein
MPSPVTFTSAGSQSTAAYSSGAPSNLQRAVLKVHKPPQSGGTGQPPGDWMFDIEFQFNPKEFSVSKNAKWGRDAQPNAKKSAPPQFKGSDPAKLSLEMFIDATDKMNDAVVKKVEQLFTCCVATEDSRQHKKPSPPWVIFKWGGMTGFPAYVASVTAKYTLFTPAGTPVRAICTVNLEEISGELGGQNPTSGALAARDTHVLVAGDSLPSVAFRAYGDAGRWREIADANDIDDPMRLRPGTRLLVPALEELDG
>NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein
MANETFTNTLVVEVEGTALPDDVRVMLGYAYVDDSRNLPDTFVLRFRDPGAVVLEKGKFKVGAKIKLKVQTSDPEGPQDLLSGEVTAVAVDLDPHGTFTEVRGYDHAHRLFRGRRVAAYPNMTIADVVRKVARRANLPAGKIDDVKGVGGRPNAQLSQDNVSDWEFLSRLADVVGAQIAVRDGKLNFELPEKPSGAPSPTTKATADPLVLEAHGTLLSLRASVTAAEQVPEVRVNGWDYENKQPITATATPKNAGTDVPGVDPVALAGKFASPPFLDAAAPRRTQGEADATAKALADRFGSACTELDGVAKGNPKLRAGAAVTLTGVGQPFSGKYTLTSTRHLFNDEVGYTTEFAVSGRQERSLYGLVAGGAKPSSWPGVVPAQVTDLKDPAKLGRVKLTFPWLDKEFTSTWARTVQPGAGKDRGALVLPEVGDEVLVGFEHGDFEAPYVLGGLYNSKDTAPSKFTKAVVDGNSGEVALRGFVSRKGHKLEFAEDDGIILSSGDAKFVVKIDQKNQVIEVTSGKSVTVKAQNGVSIDAGSGPLELKGQKVSVKSQTDASIEASSQLKLNGTAGVKVEGATVSVAGQGQTELTASGVVTVRGSVVKIN
>NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein
MPPAARVGDPTGHPGVIAGPGVPTVLIGGLPAANVGTLHTCSFPPPAVHPPTPIAPPGCPTVLIGGMPAARMGDMATCGAPIVMGCPTVLIGG
>NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein
MTGKDFLGRGLAFPLHTDATGSIALVGGEREVVESIRLILATSPGERPMRPEFGCAVHDLVFAPADAATAGQIAYEVRTSLERWEPRITLDDVVVSFDQADRGTLLIDIRYRLRGTNDPRNLVFPFYVIPPHESAALDSQADGA
>NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein
MRTGIPGLPSPHPIGEQLPSVYAEDRFVQGFTGALDEVLAPVISTLDNFSGYLDPGVAPADFVGWLAHWVALGVDESWHPDQLRQLVTRSVELHRWRGTRRGLTEHVRLLTGGAVEVTDSGGVVADPQPGAPLPDPGPPWVQVRVRVPDPARVDVRRLTATVVDAVPAHVRVTVEVLEG
>NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein
MRANRAVAGIAVVAVLGGWALSGALAPTEAQAPAPVASPYRVGYVSEATTGLYQATGEGAEPALPRAVGGVDSDASAGTGGIVWVSHRAAAAGGAERDGELWFLRDGAPTALQLTNDDAVDLHPALSPDGRTVAFASERTGSRKLFVIGVDGRGLRQVTSGPATDDSPSWSPDGTRLAFSSTRDDPAGDIYTVGVDGGTPARLTTDPAADTQPAWGPARIAFTTTRFHPAGDVVLMAEAGGAVTRAVPDPGDSSEPAWSPDGRLAFTTRAKDPSGDVRQIVGETVTDISALKDIGETEPTFRSDGRPVFTELRASGTTDIWSADAAGGDRRDLTNRPGADEFDPAFSADGSQLAYTQGGRGDSVATEIIVANADGSGPRPLTGPTDGTKRERHPAWSPDATAIAFTVTVGGGESSRDVVRIARVADGRILGEIPIPPYLSGNDSQPVWSADGTKVTLTRAASRIAPPPPGRVDPSVVDIPVGQGSSAAIEKKVPTDKVPAKPDIVLLMDQTSSMGDALAAMKASLTQVMTTISTAQPDAQYAAVAFGDRDDVADKNNPNGRLFQVQRDLTKDQAAITKAFENITIGGGIDTPEDWIYALDRLATGAVTFRPDSSRIIVLVGDAPSHDPSGDHLHHDQGVTLTQAIEHLKAQGIRVVGVSAAGSGGGLDSDPAHQATQVTTATDGVLASTDPANISAVITEKIGDLRVKVQPVPFCDPGLTLTFTPEGTQQVPGGTTANFTEFAAVAPTAPLGAFLHCRVEFRLAGESTVRAGYTEDVTVRVKDPRLPLITLHDKTVTGTAPTVVEYPVTAIDADRETRLTPFCSPSSGSLFPVGATTVTCTATGRGGTATESAVVSVDPGGEYRQELWQVALAAGPDSVVPGTQRNLSPSFGTPCGVGRQGSADVSPDGAALVFQNDRSQLCVAPADGGRARVLVQSGDEGESLNDPAWSPDGTLVAYDSAFSESVPSILIVPSAGGTPRPLIDGPGGAGQPAFQRVADVGVTATAVPAAIPFSGLTTFEFVVTNHGVAAAPGVGLFVRLTAGLRPQAPITSAGTCTPDLVCALGTLAPGAQARVRFSATGAEPGPQAATGTVTTAGQDADARDNSATAVVTVGEKPVPPVTQGSLSVGLAVSAVPLFVGGDDVVLTFLVHNGSGAPMPDVRLVTQLPPQLPATSVSPGCAPGGGSCALGTLAPGQTVEIRIALAAKAAADTPVAGTVSTSGPDTDPRDNTASARVVIRQPVVTVDPGVGPLGSVPRVTGTDFPPGATVGLAWSAGISETPGLATVGVDGKFEAQFLIFHHDLTGPRTVSVTSVSGPKFGTAQSNPILVVLRTEQPPFITRG
>NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein
MGATATLSEAGLVAEPGQETSCTVTVRNAGQVVDQFAIDVVGDASGWATAEPATVNLMPGETGTVTVRFAPPRSSDVPAGTIPFGVRVFSSEDPAGSVVEEGTVELGAFTEVTAEIVPAKVEGSSKADFEVAVDNRGNRPVAVELSPLDPEDELDFRLERDRAELAPGTAAFIRMRTRPRKRFLRGQPVRHRFQVFVVADGAEPLKTEGTMVQRQLLPKWLLPVLAALLILLLALVTLWFTVLRPAVKSAAREAAEEQNHEIVKAAQDAGAGADQAKKNADQAKQNSEQAMKAVGLTPPGDASAAPGTGAGPGTPPPTRVSNAAADGTPTDFRVAADAKTDSNVNRFAEFPYTLPDATKTLVITDLILQNPRGDAGTLRLLRDSGGTKTVLLEVGLSNFRDLDHHWLQAWRFQPGDKIVLAVSCQNPADRGHCTPSVSFSGRVE
>NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor
MITDQVPVLLHATDTITHAGVTAALRSRPEIRFADEDSGEPAVVLVIVERLNEQARQLLRSLQCAGHTGVVLVAGEVEDSELLDVVGNGVSAIIRRADATPDTLVRLVKAAAVGEGALPPDLLGRLLSRVSRLQRDVLRPNGWDLAGMSQRETRVLRLVADGFETKEIADQLSYSERTVKSILHDITNRFQLRNRAHAVAFAMREGLI
>NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor
MFGSLRVLVVDDHPVFRAALCAMLDATDGMEVAGEAADGLTAVTDAGRLEPDVVLMDLNLPDLDGIEATRRIVSASPHTGVLMLTMFENEAAVFAAMRAGARGYLLKGARNEQIIRAVRVIGDGEAIFSPAIATRVLSLLGTATPRDESFPRLTLREQEILRLVARGMGNASIAEELVLSQKTVRNHVSHIFRKLRVTDRSQAIAKAKEAGIARSE
>NC_017186.1|WP_003098516.1|5357967_5358126_-|hypothetical-protein
MTYAADRLHEEVAYVAYHLHWSLDDILDLEHPDRLTYVAEIARINTRMSQGR
>NC_017186.1|WP_013226671.1|5358122_5358572_-|hypothetical-protein
MRRVMASAPVEEAPAAPAGEPRAERPKLRTEFAFELPRGYVDDEGKVHHSGVMRLATARDELIPLRDDRVRENSAFLTVVLLARVVTRIGDITDVHAGVIENLFASDLAFLQDMYRRVNSEGHTRAGVACPECGHSFVVDVAGGRLGES
>NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein
MALPDLDKAVGHSFGLEIDGVQIKQISEVSGLKMEQDVIELKQNTADGKYVIKKLPGRPKAGEVTLTRGLTEDNSFEKWVKDAHFGKMATARKGGAIIVYDYEGTALKRYKLTNAWPKSLEIGSLKAGDTSVLTEKLVITYEQMEVE
>NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein
MPTYLTPGVYVEEIEAGARPIEGVGTAVAAFVGFAADGPFNTPTLVSNWGQFTQTFGDFIEGCYLAQSVYGYFLNGGSNCYIVRIGGSRAQNNGAAPKQIEARQAVLGGYRFVAKELPEGKQGGEITVEVAEPTGDNPAEDRFTVLVKQDGKVVETHNVTTKRTKENVVTAVREKSSLITIEEVATGGAVTKPDKGTAVLSAPPKDPEAPPVPRRVAANDYVGDVADRTGFGGLEAIDEITMVAAPDLMAAYQRDLIDLDTVKAVQLAMIAHCELMGDRMAIIDPPPALNPQEIRSWRMDAAGYDSKYAALYYPWVQVLDPASGTNAFIPPSGHMAGVWARTDATRGVHKAPANEVVRGALALETHLTKAEQELLNPIGVNCVRSFSGKGIRVWGARTLSSDPAWRYLNVRRLFNYLEESILGGTQWVVFEPNDDALWARIRRTISAFLVMEWRKGALFGLTPDEAFFVKCDRETNPAEGIDLGQVICEVGIAPVKPAEFVIFRLAQMSGGTSLVNE
>NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein
MLRLQASAGNAAVSGLVALQRQGCPAPPVAPPGVTPASDPKFQSLKKDVGGQAKTAKAHPPAGAEVKKAQDAAVAPPDDKDAQAKAAQADKMAAAKPAGFDKAAFIAAVNAAIAKQAPKNLDEADKFATSGKADQVKAEVLGKVTSGKDASAKDVTDRTKEPPDPGRAVEKPVTPLPEPPAAPVLAPPDARKATPDKAPPEQTDLRAGQCETQGAMAEAGVTDQQLAESNEPEFTGALAAKREGEQHTASAPAAVRESEAGQLAAVTGAAQASGQAAMAGMTGARSSSAQRGQAAKSATKSKDEQDRARITGEIKAIFDETKTKVEGVLGALDDQVAKKFEAGEAQAKAAFTADHQARMKRFKDERYDGITGAARWAYDLFADLPAEANNLFLEAKKVYESKMQGVIGDIADFVGQKLGEAKQLIADGRARVQQKVASQSPALRKIAGEAAKEFGGQFDDLEKSVDEKQDALVEDLAQKYGEARNAVDEEIKTLQAENKGLWSKAKEAVGGAIETILKLKDMLLGVLSRAANAVGLIIAKPIEFLGNLVNAVKTGVMNFGANIVEHLKEGLKGWLLGNLASAGIEIPEALDAKGILKMVLSLLGLTWASVRARILRFIPEPVLAKLEQTLDVVKILLTEGVPGLWRWIVAKLGDLKEMVLGQIKEFVIEKIVKAGITWIISMLNPAAAFIKACKAIYDIVMFFVDKAAQIKEFVDSVLDSVESIARGGSGAVAGLIERTLAKALPMVLGFLASLLGLGGISEKIKSVLEKVQAPVGKVIDSVVGTIVKAGKKVWSKFKGKKGSGVPDPRSAGQKQQALAQAKQAADAEMRKPNATQHTVEAALPKIKDTYQLTTIALVPTSNGKFKTHLEVNPTDDTGELPLGPMAPVDEAKVYLGKRFVVKATNRVAKVTDVRPDGWVTLQYELERNAGGRSKSSEGRPAFPVLKFLANTPNGGPELAPAEGGASQTQYTIDGKTLRPEYHDVRAVFYGGSHKYSGHDAAKIAAVMRPDGRTFTCPGVPFLGIAPHVAARVKPNNADNYALDHRKSVAGHWNTQGREKSQTDRSQFYADPGNLEVLCGSCNSKKGSKDADTGAAERYRKDVEIPGFTGPDGKE
>NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein
MRGHSHENDLEPALRPKGDRIERDDHDLLGRAAAAGRTDVLGPAGMLGLQRAAGNAGTASLVEEDRSPVHDVVGSGGGTPLDTSTRVDMESRFGHDFGDVRVHTDGAAHDSAKSVNAQAYTVGSNIVFQRDKYDPSSDSGKHMLAHELTHVVQQRSGPVDGTDAGGGVKVSDPSDRFEREAVANADRLMSSPAPAGPAVQRCEDGGHAAHSEDSAAVQREEAPEAEEGEEKMAQTFVQREEEAEEEA
>NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein
MSLEYLFERLARLEQRIRDAVDSRRAADPNPDDPFRGLYLSNETIDALLEGLREPFTPFTDSVPDGRLRPLAERAGLTGVDVELLLVALAPDLDSRFEQFYGYLNDDVTRRRASAGLALRLCGIPEASAAGRARLDADSPLVTCGLLTVGEDERPFLSRTLRVPDRVVNHLLGDDRLAPELAGCAHLGTELVEVPGRERLARAIRGRVGLVYLKEQPGGGAEELGVGALAAAGYPALVVDAERWQAEPGHAELTASLRREALLRGAGIVLGPVEDPRLEALAHPAIPLVAHGTGAWDPRWSATPPLQLDALPLSAADRAELWRSRLEGRLAPGVDPGEETAHFVLGPGQIARAAKAASVTALADDGLVRTAHVRAGARSQNAAGLQRLARRIEPVVGWADLVLPAGVLSLLDELAARARYRDQVLDDWRMRPGGGRGRGVTGLFAGDSGTGKTMSAEVIASSLGLDLYTVNLATVVDKYVGETEKNLERIFTEASGVNGVLLFDEADAIFGKRSEVRDAHDRYANIESAYLLQRMETFDGIAVLATNLRANLDEAFTRRLDVIVDFPLPDVELRHRLWDRCLGVRMPRGADLDLGFLAEAFELAGGHIRSAAVTGAYLAAEAGRPVAMSDLVGAVAREYRKLGRLCLDREFGPYLAMVTDG
>NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein
MIHEVDEALRRLVKDEALRGSEVDVAFDAPTKDWAARRNAPTVNIYLYDVREDMRRRSRGLLNEYDQRGEVAARHLPPKHVKLSYLVTAWTQRPEDEHRVLSDLLLGLLRHEAVPAEVLSGSLAEMGLPVPMTVALPPPEDRAFADVWTALGGELKPSLDVVVSAPIHSGRVYPAGPPAKEGLKLDTGDGELLGHHVSATGAVEGQRRVAMARTHRKPR
>NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase
MLVENVVVAAEYRRSGVGAALVEAAFAIARQARCYKVLLAVPVRPGSRPERFHARSEPGPRGADPARSASAVTGNVSPGRSRSRCPRRGRPRRCRGPWRRPPP
>NC_017186.1|WP_013226678.1|5368207_5369029_-|hypothetical-protein
MSTLRRLAVAGAFALPLSLVIAGPATAHPLGWPNDSWSAESSSSWAGIGGAGTTDTDEGSTWWGHHWSDSDAAVAGIGGAYVTHNGESGDDGWNHAWHHPAHNGWQDGDDDDCDYDAGDQHHYVYGDNDDAPDVVDHHHHVMSHPDPVNQEPVGYVAHPVYDADDDGADDVGYYAEQHSAGVDGATSAHVVSHAGEHHATYDAEKYTAGPHGASSEGAHALAVPDYAGYHAWYTAAGVGGAAAHSVTAVADATDHDNVWADHDADSDYDYDRG

Crispr_ID: NC_017186_15

• CRISPR_ID: NC_017186_15
• CRISPR_location: 5355889-5356032
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017186_15

Consensus_repeat	Method
GCCCGCAACACCGGAAGCGGCGG	CRISPRCasFinder

spacers of NC_017186_15

>15.1|5355912|37|NC_017186|CRISPRCasFinder
TGCGGCGGGCCCGGTCACCGGTGCCAATCCATCGGCA
>15.2|5355972|37|NC_017186|CRISPRCasFinder
CACGGCGGCCCCGGTTACCGGCGCCGACCCGTCGACG

CRISPR arrays and Neighbor proteins around NC_017186_15

CRISPR arrays

The CRISPR arrays of NC_017186_15

>merge|NC_017186|15|5355889-5356032|CRISPRCasFinder
GCCCGTGACACGGGAAGCGGCGGTGCGGCGGGCCCGGTCACCGGTGCCAATCCATCGGCAGCCCGCGCAACCGGAAGCGGCGACACGGCGGCCCCGGTTACCGGCGCCGACCCGTCGACGGCCCGCGCCACCGGAAGCGGAGGT

>NC_017186|15|14|5355889-5356032|CRISPRCasFinder
GCCCGTGACACGGGAAGCGGCGG	TGCGGCGGGCCCGGTCACCGGTGCCAATCCATCGGCA
GCCCGCGCAACCGGAAGCGGCGA	CACGGCGGCCCCGGTTACCGGCGCCGACCCGTCGACG
GCCCGCGCCACCGGAAGCGGAGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein	unknown	unknown	gnl|CDD|223540
NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein	unknown	unknown	gnl|CDD|269824
NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein	unknown	unknown	gnl|CDD|274305
NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein	unknown	unknown	gnl|CDD|274050
NC_017186.1|WP_003098516.1|5357967_5358126_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226671.1|5358122_5358572_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein	unknown	unknown	gnl|CDD|377431
NC_017186.1|WP_013226678.1|5368207_5369029_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein	unknown	unknown	gnl|CDD|377718
NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein	unknown	unknown	gnl|CDD|226028
NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|212030
NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein	unknown	unknown	gnl|CDD|379338
NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein	unknown	unknown	gnl|CDD|224387
NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein	unknown	unknown	gnl|CDD|273730
NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein	unknown	unknown	gnl|CDD|379449

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	5.49739e-27
NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein	gnl|CDD|269824	cd14739, PAAR_3, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	1.82721e-26
NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.83282e-06
NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein	gnl|CDD|274305	TIGR02800, Protein_TolB, tol-pal system beta propeller repeat protein TolB. Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	5.17064e-29
NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.00618e-70
NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.067e-22
NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein	gnl|CDD|274050	TIGR02242, putative_secreted_protein, phage tail protein domain. This model describes a region of sequence similarity shared by a number of uncharacterized proteins in bacterial genomes, including Geobacter sulfurreducens PCA, Mesorhizobium loti, Streptomyces coelicolor A3(2), Gloeobacter violaceus PCC 7421, and Myxococcus xanthus. In all cases, the genomic region resembles a phage tail region, based on tentative identifications of neighboring genes. A region of this domain resembles a region of TIGR01634, another phage tail protein model. [Mobile and extrachromosomal element functions, Prophage functions].	2.29002e-24
NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein	gnl|CDD|377431	pfam04965, GPW_gp25, Gene 25-like lysozyme. This family includes the phage protein Gene 25 from T4 which is a structural component of the outer wedge of the baseplate that has acidic lysozyme activity. The family also includes relatives from bacteria that are also presumably lysozymes.	1.3903e-34
NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	1.1604e-06
NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	1.46325e-38
NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	2.80163e-33
NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein	gnl|CDD|226028	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only].	1.80502e-61
NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	1.22178e-07
NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein	gnl|CDD|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	5.72344e-33
NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein	gnl|CDD|224387	COG1470, COG1470, Predicted membrane protein [Function unknown].	0.00025614
NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein	gnl|CDD|273730	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein. This model represents the Vgr family of proteins, associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region, VGXXXXXX, found in the Vgr of Rhs classes G and E.	3.59266e-20
NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein	gnl|CDD|379449	pfam14065, DUF4255, Protein of unknown function (DUF4255). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 320 amino acids in length.	9.23209e-48

Protein sequences

>NC_017186.1|WP_013226669.1|5354547_5354994_-|phage-tail-protein
MPDTEEAVAVCYVVKLDDKNLGNLGAFSSCDGLGCEFVMEQREEGGNNGMVWQLPTRIKYSNIKLSRPVTEASSQITKWFASLAGGIERKTATIEARTLEGKVIASWALEGVVPVRWSGPQLSPDSPKVATETLELAHHGFLSPAKKG
>NC_017186.1|WP_013226668.1|5353782_5354544_-|LysM-peptidoglycan-binding-domain-containing-protein
MPSPVTFTSAGSQSTAAYSSGAPSNLQRAVLKVHKPPQSGGTGQPPGDWMFDIEFQFNPKEFSVSKNAKWGRDAQPNAKKSAPPQFKGSDPAKLSLEMFIDATDKMNDAVVKKVEQLFTCCVATEDSRQHKKPSPPWVIFKWGGMTGFPAYVASVTAKYTLFTPAGTPVRAICTVNLEEISGELGGQNPTSGALAARDTHVLVAGDSLPSVAFRAYGDAGRWREIADANDIDDPMRLRPGTRLLVPALEELDG
>NC_017186.1|WP_013226667.1|5351966_5353790_-|VgrG-related-protein
MANETFTNTLVVEVEGTALPDDVRVMLGYAYVDDSRNLPDTFVLRFRDPGAVVLEKGKFKVGAKIKLKVQTSDPEGPQDLLSGEVTAVAVDLDPHGTFTEVRGYDHAHRLFRGRRVAAYPNMTIADVVRKVARRANLPAGKIDDVKGVGGRPNAQLSQDNVSDWEFLSRLADVVGAQIAVRDGKLNFELPEKPSGAPSPTTKATADPLVLEAHGTLLSLRASVTAAEQVPEVRVNGWDYENKQPITATATPKNAGTDVPGVDPVALAGKFASPPFLDAAAPRRTQGEADATAKALADRFGSACTELDGVAKGNPKLRAGAAVTLTGVGQPFSGKYTLTSTRHLFNDEVGYTTEFAVSGRQERSLYGLVAGGAKPSSWPGVVPAQVTDLKDPAKLGRVKLTFPWLDKEFTSTWARTVQPGAGKDRGALVLPEVGDEVLVGFEHGDFEAPYVLGGLYNSKDTAPSKFTKAVVDGNSGEVALRGFVSRKGHKLEFAEDDGIILSSGDAKFVVKIDQKNQVIEVTSGKSVTVKAQNGVSIDAGSGPLELKGQKVSVKSQTDASIEASSQLKLNGTAGVKVEGATVSVAGQGQTELTASGVVTVRGSVVKIN
>NC_017186.1|WP_013226666.1|5351672_5351954_-|PAAR-domain-containing-protein
MPPAARVGDPTGHPGVIAGPGVPTVLIGGLPAANVGTLHTCSFPPPAVHPPTPIAPPGCPTVLIGGMPAARMGDMATCGAPIVMGCPTVLIGG
>NC_017186.1|WP_013226665.1|5351230_5351665_-|GPW/gp25-family-protein
MTGKDFLGRGLAFPLHTDATGSIALVGGEREVVESIRLILATSPGERPMRPEFGCAVHDLVFAPADAATAGQIAYEVRTSLERWEPRITLDDVVVSFDQADRGTLLIDIRYRLRGTNDPRNLVFPFYVIPPHESAALDSQADGA
>NC_017186.1|WP_013226663.1|5348732_5349272_-|phage-tail-protein
MRTGIPGLPSPHPIGEQLPSVYAEDRFVQGFTGALDEVLAPVISTLDNFSGYLDPGVAPADFVGWLAHWVALGVDESWHPDQLRQLVTRSVELHRWRGTRRGLTEHVRLLTGGAVEVTDSGGVVADPQPGAPLPDPGPPWVQVRVRVPDPARVDVRRLTATVVDAVPAHVRVTVEVLEG
>NC_017186.1|WP_013226661.1|5343670_5347699_-|PD40-domain-containing-protein
MRANRAVAGIAVVAVLGGWALSGALAPTEAQAPAPVASPYRVGYVSEATTGLYQATGEGAEPALPRAVGGVDSDASAGTGGIVWVSHRAAAAGGAERDGELWFLRDGAPTALQLTNDDAVDLHPALSPDGRTVAFASERTGSRKLFVIGVDGRGLRQVTSGPATDDSPSWSPDGTRLAFSSTRDDPAGDIYTVGVDGGTPARLTTDPAADTQPAWGPARIAFTTTRFHPAGDVVLMAEAGGAVTRAVPDPGDSSEPAWSPDGRLAFTTRAKDPSGDVRQIVGETVTDISALKDIGETEPTFRSDGRPVFTELRASGTTDIWSADAAGGDRRDLTNRPGADEFDPAFSADGSQLAYTQGGRGDSVATEIIVANADGSGPRPLTGPTDGTKRERHPAWSPDATAIAFTVTVGGGESSRDVVRIARVADGRILGEIPIPPYLSGNDSQPVWSADGTKVTLTRAASRIAPPPPGRVDPSVVDIPVGQGSSAAIEKKVPTDKVPAKPDIVLLMDQTSSMGDALAAMKASLTQVMTTISTAQPDAQYAAVAFGDRDDVADKNNPNGRLFQVQRDLTKDQAAITKAFENITIGGGIDTPEDWIYALDRLATGAVTFRPDSSRIIVLVGDAPSHDPSGDHLHHDQGVTLTQAIEHLKAQGIRVVGVSAAGSGGGLDSDPAHQATQVTTATDGVLASTDPANISAVITEKIGDLRVKVQPVPFCDPGLTLTFTPEGTQQVPGGTTANFTEFAAVAPTAPLGAFLHCRVEFRLAGESTVRAGYTEDVTVRVKDPRLPLITLHDKTVTGTAPTVVEYPVTAIDADRETRLTPFCSPSSGSLFPVGATTVTCTATGRGGTATESAVVSVDPGGEYRQELWQVALAAGPDSVVPGTQRNLSPSFGTPCGVGRQGSADVSPDGAALVFQNDRSQLCVAPADGGRARVLVQSGDEGESLNDPAWSPDGTLVAYDSAFSESVPSILIVPSAGGTPRPLIDGPGGAGQPAFQRVADVGVTATAVPAAIPFSGLTTFEFVVTNHGVAAAPGVGLFVRLTAGLRPQAPITSAGTCTPDLVCALGTLAPGAQARVRFSATGAEPGPQAATGTVTTAGQDADARDNSATAVVTVGEKPVPPVTQGSLSVGLAVSAVPLFVGGDDVVLTFLVHNGSGAPMPDVRLVTQLPPQLPATSVSPGCAPGGGSCALGTLAPGQTVEIRIALAAKAAADTPVAGTVSTSGPDTDPRDNTASARVVIRQPVVTVDPGVGPLGSVPRVTGTDFPPGATVGLAWSAGISETPGLATVGVDGKFEAQFLIFHHDLTGPRTVSVTSVSGPKFGTAQSNPILVVLRTEQPPFITRG
>NC_017186.1|WP_013226660.1|5342172_5343507_-|hypothetical-protein
MGATATLSEAGLVAEPGQETSCTVTVRNAGQVVDQFAIDVVGDASGWATAEPATVNLMPGETGTVTVRFAPPRSSDVPAGTIPFGVRVFSSEDPAGSVVEEGTVELGAFTEVTAEIVPAKVEGSSKADFEVAVDNRGNRPVAVELSPLDPEDELDFRLERDRAELAPGTAAFIRMRTRPRKRFLRGQPVRHRFQVFVVADGAEPLKTEGTMVQRQLLPKWLLPVLAALLILLLALVTLWFTVLRPAVKSAAREAAEEQNHEIVKAAQDAGAGADQAKKNADQAKQNSEQAMKAVGLTPPGDASAAPGTGAGPGTPPPTRVSNAAADGTPTDFRVAADAKTDSNVNRFAEFPYTLPDATKTLVITDLILQNPRGDAGTLRLLRDSGGTKTVLLEVGLSNFRDLDHHWLQAWRFQPGDKIVLAVSCQNPADRGHCTPSVSFSGRVE
>NC_017186.1|WP_013226659.1|5341539_5342166_+|response-regulator-transcription-factor
MITDQVPVLLHATDTITHAGVTAALRSRPEIRFADEDSGEPAVVLVIVERLNEQARQLLRSLQCAGHTGVVLVAGEVEDSELLDVVGNGVSAIIRRADATPDTLVRLVKAAAVGEGALPPDLLGRLLSRVSRLQRDVLRPNGWDLAGMSQRETRVLRLVADGFETKEIADQLSYSERTVKSILHDITNRFQLRNRAHAVAFAMREGLI
>NC_017186.1|WP_013226658.1|5340783_5341434_+|response-regulator-transcription-factor
MFGSLRVLVVDDHPVFRAALCAMLDATDGMEVAGEAADGLTAVTDAGRLEPDVVLMDLNLPDLDGIEATRRIVSASPHTGVLMLTMFENEAAVFAAMRAGARGYLLKGARNEQIIRAVRVIGDGEAIFSPAIATRVLSLLGTATPRDESFPRLTLREQEILRLVARGMGNASIAEELVLSQKTVRNHVSHIFRKLRVTDRSQAIAKAKEAGIARSE
>NC_017186.1|WP_003098516.1|5357967_5358126_-|hypothetical-protein
MTYAADRLHEEVAYVAYHLHWSLDDILDLEHPDRLTYVAEIARINTRMSQGR
>NC_017186.1|WP_013226671.1|5358122_5358572_-|hypothetical-protein
MRRVMASAPVEEAPAAPAGEPRAERPKLRTEFAFELPRGYVDDEGKVHHSGVMRLATARDELIPLRDDRVRENSAFLTVVLLARVVTRIGDITDVHAGVIENLFASDLAFLQDMYRRVNSEGHTRAGVACPECGHSFVVDVAGGRLGES
>NC_017186.1|WP_013226672.1|5358576_5359020_-|phage-tail-protein
MALPDLDKAVGHSFGLEIDGVQIKQISEVSGLKMEQDVIELKQNTADGKYVIKKLPGRPKAGEVTLTRGLTEDNSFEKWVKDAHFGKMATARKGGAIIVYDYEGTALKRYKLTNAWPKSLEIGSLKAGDTSVLTEKLVITYEQMEVE
>NC_017186.1|WP_013226673.1|5359091_5360645_-|phage-tail-sheath-family-protein
MPTYLTPGVYVEEIEAGARPIEGVGTAVAAFVGFAADGPFNTPTLVSNWGQFTQTFGDFIEGCYLAQSVYGYFLNGGSNCYIVRIGGSRAQNNGAAPKQIEARQAVLGGYRFVAKELPEGKQGGEITVEVAEPTGDNPAEDRFTVLVKQDGKVVETHNVTTKRTKENVVTAVREKSSLITIEEVATGGAVTKPDKGTAVLSAPPKDPEAPPVPRRVAANDYVGDVADRTGFGGLEAIDEITMVAAPDLMAAYQRDLIDLDTVKAVQLAMIAHCELMGDRMAIIDPPPALNPQEIRSWRMDAAGYDSKYAALYYPWVQVLDPASGTNAFIPPSGHMAGVWARTDATRGVHKAPANEVVRGALALETHLTKAEQELLNPIGVNCVRSFSGKGIRVWGARTLSSDPAWRYLNVRRLFNYLEESILGGTQWVVFEPNDDALWARIRRTISAFLVMEWRKGALFGLTPDEAFFVKCDRETNPAEGIDLGQVICEVGIAPVKPAEFVIFRLAQMSGGTSLVNE
>NC_017186.1|WP_013226674.1|5360926_5364271_+|hypothetical-protein
MLRLQASAGNAAVSGLVALQRQGCPAPPVAPPGVTPASDPKFQSLKKDVGGQAKTAKAHPPAGAEVKKAQDAAVAPPDDKDAQAKAAQADKMAAAKPAGFDKAAFIAAVNAAIAKQAPKNLDEADKFATSGKADQVKAEVLGKVTSGKDASAKDVTDRTKEPPDPGRAVEKPVTPLPEPPAAPVLAPPDARKATPDKAPPEQTDLRAGQCETQGAMAEAGVTDQQLAESNEPEFTGALAAKREGEQHTASAPAAVRESEAGQLAAVTGAAQASGQAAMAGMTGARSSSAQRGQAAKSATKSKDEQDRARITGEIKAIFDETKTKVEGVLGALDDQVAKKFEAGEAQAKAAFTADHQARMKRFKDERYDGITGAARWAYDLFADLPAEANNLFLEAKKVYESKMQGVIGDIADFVGQKLGEAKQLIADGRARVQQKVASQSPALRKIAGEAAKEFGGQFDDLEKSVDEKQDALVEDLAQKYGEARNAVDEEIKTLQAENKGLWSKAKEAVGGAIETILKLKDMLLGVLSRAANAVGLIIAKPIEFLGNLVNAVKTGVMNFGANIVEHLKEGLKGWLLGNLASAGIEIPEALDAKGILKMVLSLLGLTWASVRARILRFIPEPVLAKLEQTLDVVKILLTEGVPGLWRWIVAKLGDLKEMVLGQIKEFVIEKIVKAGITWIISMLNPAAAFIKACKAIYDIVMFFVDKAAQIKEFVDSVLDSVESIARGGSGAVAGLIERTLAKALPMVLGFLASLLGLGGISEKIKSVLEKVQAPVGKVIDSVVGTIVKAGKKVWSKFKGKKGSGVPDPRSAGQKQQALAQAKQAADAEMRKPNATQHTVEAALPKIKDTYQLTTIALVPTSNGKFKTHLEVNPTDDTGELPLGPMAPVDEAKVYLGKRFVVKATNRVAKVTDVRPDGWVTLQYELERNAGGRSKSSEGRPAFPVLKFLANTPNGGPELAPAEGGASQTQYTIDGKTLRPEYHDVRAVFYGGSHKYSGHDAAKIAAVMRPDGRTFTCPGVPFLGIAPHVAARVKPNNADNYALDHRKSVAGHWNTQGREKSQTDRSQFYADPGNLEVLCGSCNSKKGSKDADTGAAERYRKDVEIPGFTGPDGKE
>NC_017186.1|WP_013226675.1|5364304_5365048_-|DUF4157-domain-containing-protein
MRGHSHENDLEPALRPKGDRIERDDHDLLGRAAAAGRTDVLGPAGMLGLQRAAGNAGTASLVEEDRSPVHDVVGSGGGTPLDTSTRVDMESRFGHDFGDVRVHTDGAAHDSAKSVNAQAYTVGSNIVFQRDKYDPSSDSGKHMLAHELTHVVQQRSGPVDGTDAGGGVKVSDPSDRFEREAVANADRLMSSPAPAGPAVQRCEDGGHAAHSEDSAAVQREEAPEAEEGEEKMAQTFVQREEEAEEEA
>NC_017186.1|WP_013226676.1|5365151_5367137_-|ATP-binding-protein
MSLEYLFERLARLEQRIRDAVDSRRAADPNPDDPFRGLYLSNETIDALLEGLREPFTPFTDSVPDGRLRPLAERAGLTGVDVELLLVALAPDLDSRFEQFYGYLNDDVTRRRASAGLALRLCGIPEASAAGRARLDADSPLVTCGLLTVGEDERPFLSRTLRVPDRVVNHLLGDDRLAPELAGCAHLGTELVEVPGRERLARAIRGRVGLVYLKEQPGGGAEELGVGALAAAGYPALVVDAERWQAEPGHAELTASLRREALLRGAGIVLGPVEDPRLEALAHPAIPLVAHGTGAWDPRWSATPPLQLDALPLSAADRAELWRSRLEGRLAPGVDPGEETAHFVLGPGQIARAAKAASVTALADDGLVRTAHVRAGARSQNAAGLQRLARRIEPVVGWADLVLPAGVLSLLDELAARARYRDQVLDDWRMRPGGGRGRGVTGLFAGDSGTGKTMSAEVIASSLGLDLYTVNLATVVDKYVGETEKNLERIFTEASGVNGVLLFDEADAIFGKRSEVRDAHDRYANIESAYLLQRMETFDGIAVLATNLRANLDEAFTRRLDVIVDFPLPDVELRHRLWDRCLGVRMPRGADLDLGFLAEAFELAGGHIRSAAVTGAYLAAEAGRPVAMSDLVGAVAREYRKLGRLCLDREFGPYLAMVTDG
>NC_017186.1|WP_013226677.1|5367133_5367793_-|DUF4255-domain-containing-protein
MIHEVDEALRRLVKDEALRGSEVDVAFDAPTKDWAARRNAPTVNIYLYDVREDMRRRSRGLLNEYDQRGEVAARHLPPKHVKLSYLVTAWTQRPEDEHRVLSDLLLGLLRHEAVPAEVLSGSLAEMGLPVPMTVALPPPEDRAFADVWTALGGELKPSLDVVVSAPIHSGRVYPAGPPAKEGLKLDTGDGELLGHHVSATGAVEGQRRVAMARTHRKPR
>NC_017186.1|WP_071831583.1|5367981_5368293_+|GNAT-family-N-acetyltransferase
MLVENVVVAAEYRRSGVGAALVEAAFAIARQARCYKVLLAVPVRPGSRPERFHARSEPGPRGADPARSASAVTGNVSPGRSRSRCPRRGRPRRCRGPWRRPPP
>NC_017186.1|WP_013226678.1|5368207_5369029_-|hypothetical-protein
MSTLRRLAVAGAFALPLSLVIAGPATAHPLGWPNDSWSAESSSSWAGIGGAGTTDTDEGSTWWGHHWSDSDAAVAGIGGAYVTHNGESGDDGWNHAWHHPAHNGWQDGDDDDCDYDAGDQHHYVYGDNDDAPDVVDHHHHVMSHPDPVNQEPVGYVAHPVYDADDDGADDVGYYAEQHSAGVDGATSAHVVSHAGEHHATYDAEKYTAGPHGASSEGAHALAVPDYAGYHAWYTAAGVGGAAAHSVTAVADATDHDNVWADHDADSDYDYDRG

Crispr_ID: NC_017186_18

• CRISPR_ID: NC_017186_18
• CRISPR_location: 5780710-5780792
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_18

Consensus_repeat	Method
CGGGGCGGAGCCCCGGTTGTCAC	CRISPRCasFinder

spacers of NC_017186_18

>18.1|5780733|37|NC_017186|CRISPRCasFinder
TGCTGTTCGGGGGTTCCGGGCGGCGGAGCCCCCGGCT

CRISPR arrays and Neighbor proteins around NC_017186_18

CRISPR arrays

The CRISPR arrays of NC_017186_18

>merge|NC_017186|18|5780710-5780792|CRISPRCasFinder
CGGGGCGGAGCCCCGGTTGTCACTGCTGTTCGGGGGTTCCGGGCGGCGGAGCCCCCGGCTCGGGGCGGAGCCCCGGTTGTCAC

>NC_017186|18|17|5780710-5780792|CRISPRCasFinder
CGGGGCGGAGCCCCGGTTGTCAC	TGCTGTTCGGGGGTTCCGGGCGGCGGAGCCCCCGGCT
CGGGGCGGAGCCCCGGTTGTCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013227042.1|5786277_5786742_-|SRPBCC-family-protein	unknown	unknown	gnl|CDD|176859
NC_017186.1|WP_013227040.1|5784760_5785561_+|GAF-and-ANTAR-domain-containing-protein	unknown	unknown	gnl|CDD|377145
NC_017186.1|WP_013227037.1|5781732_5782524_+|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|168831
NC_017186.1|WP_013227039.1|5784197_5784719_+|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|376622
NC_017186.1|WP_013227043.1|5786877_5787291_+|phage-holin-family-protein	unknown	unknown	gnl|CDD|377816
NC_017186.1|WP_013227027.1|5774885_5775749_-|non-homologous-end-joining-DNA-ligase	unknown	unknown	gnl|CDD|240131
NC_017186.1|WP_013227028.1|5775745_5776690_-|non-homologous-end-joining-DNA-ligase	unknown	unknown	gnl|CDD|235658
NC_017186.1|WP_013227026.1|5774242_5774875_+|UdgX-family-uracil-DNA-binding-protein	unknown	unknown	gnl|CDD|274850
NC_017186.1|WP_013227032.1|5778267_5778996_-|GAF-and-ANTAR-domain-containing-protein	unknown	unknown	gnl|CDD|377145
NC_017186.1|WP_013227044.1|5787287_5787593_+|DUF3618-domain-containing-protein	unknown	unknown	gnl|CDD|378834
NC_017186.1|WP_013227038.1|5782555_5784073_-|CYTH-and-CHAD-domain-containing-protein	unknown	unknown	gnl|CDD|214880
NC_017186.1|WP_013227030.1|5777635_5777833_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227031.1|5778012_5778225_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227041.1|5785639_5786113_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227036.1|5781286_5781736_+|anti-sigma-factor	unknown	unknown	gnl|CDD|235217
NC_017186.1|WP_013227033.1|5779289_5779655_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_017186.1|WP_013227025.1|5773734_5774151_-|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341390
NC_017186.1|WP_013227034.1|5779685_5780651_-|TIGR03557-family-F420-dependent-LLM-class-oxidoreductase	unknown	unknown	gnl|CDD|274645
NC_017186.1|WP_013227029.1|5776686_5777619_-|Ku-protein	unknown	unknown	gnl|CDD|238408
NC_017186.1|WP_013227035.1|5780894_5781224_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013227040.1|5784760_5785561_+|GAF-and-ANTAR-domain-containing-protein	gnl|CDD|377145	pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.	5.40439e-18
NC_017186.1|WP_013227037.1|5781732_5782524_+|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor	gnl|CDD|168831	PRK07122, PRK07122, RNA polymerase sigma factor SigF; Reviewed.	5.51906e-122
NC_017186.1|WP_013227039.1|5784197_5784719_+|hemerythrin-domain-containing-protein	gnl|CDD|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	0.00193466
NC_017186.1|WP_013227044.1|5787287_5787593_+|DUF3618-domain-containing-protein	gnl|CDD|378834	pfam12277, DUF3618, Protein of unknown function (DUF3618). This domain family is found in bacteria, and is approximately 50 amino acids in length.	9.65675e-06
NC_017186.1|WP_013227028.1|5775745_5776690_-|non-homologous-end-joining-DNA-ligase	gnl|CDD|235658	PRK05972, ligD, ATP-dependent DNA ligase; Reviewed.	5.94678e-111
NC_017186.1|WP_013227026.1|5774242_5774875_+|UdgX-family-uracil-DNA-binding-protein	gnl|CDD|274850	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain. This model represents a clade within the uracil-DNA glycosylase superfamily. Among characterized proteins, it most closely resembles the Thermus thermophilus uracil-DNA glycosylase TTUDGA, which acts uracil (deamidated cytosine) in both single-stranded DNA and U/G pairs of double-stranded DNA. This domain may occur either as a stand-alone protein or as the C-terminal domain of a fusion with another domain that always pairs with a particular radical-SAM family protein.	6.13305e-88
NC_017186.1|WP_013227032.1|5778267_5778996_-|GAF-and-ANTAR-domain-containing-protein	gnl|CDD|377145	pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.	2.17304e-18
NC_017186.1|WP_013227038.1|5782555_5784073_-|CYTH-and-CHAD-domain-containing-protein	gnl|CDD|214880	smart00880, CHAD, The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family. It has conserved histidines that may chelate metals.	4.82158e-44
NC_017186.1|WP_013227043.1|5786877_5787291_+|phage-holin-family-protein	gnl|CDD|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	1.43223e-24
NC_017186.1|WP_013227042.1|5786277_5786742_-|SRPBCC-family-protein	gnl|CDD|176859	cd07817, SRPBCC_8, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	4.64843e-53
NC_017186.1|WP_013227036.1|5781286_5781736_+|anti-sigma-factor	gnl|CDD|235217	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional.	8.97587e-13
NC_017186.1|WP_013227033.1|5779289_5779655_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.00364e-16
NC_017186.1|WP_013227025.1|5773734_5774151_-|CBS-domain-containing-protein	gnl|CDD|341390	cd04622, CBS_pair_HRP1_like, CBS pair domain found in Hypoxic Response Protein 1 (HRP1) -like proteinds. Mycobacterium tuberculosis adapts to cellular stresses by upregulation of the dormancy survival regulon. Hypoxic response protein 1 (HRP1) is encoded by one of the most strongly upregulated genes in the dormancy survival regulon. HRP1 is a 'CBS-domain-only protein; however unlike other CBS containing proteins it does not appear to bind AMP. The biological function of the protein remains unclear, but is thought to contribute to the modulation of the host immune response. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	2.74047e-44
NC_017186.1|WP_013227034.1|5779685_5780651_-|TIGR03557-family-F420-dependent-LLM-class-oxidoreductase	gnl|CDD|274645	TIGR03557, F420_G6P_family, F420-dependent oxidoreductase, G6PDH family. Members of this protein family include F420-dependent glucose-6-phosphate dehydrogenases (TIGR03554) and related proteins. All members of this family come from species that synthesize coenzyme F420, with the exception of those that belong to TIGR03885, a clade within this family in which cofactor binding may instead be directed to FMN. [Unknown function, Enzymes of unknown specificity].	3.92252e-172
NC_017186.1|WP_013227029.1|5776686_5777619_-|Ku-protein	gnl|CDD|238408	cd00789, KU_like, Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku homologs are predicted to form homodimers. It is proposed that the Ku homologs are functionally associated with ATP-dependent DNA ligase and the eukaryotic-type primase, probably as components of a double-strand break repair system.	2.75779e-104
NC_017186.1|WP_013227027.1|5774885_5775749_-|non-homologous-end-joining-DNA-ligase	gnl|CDD|240131	cd04861, LigD_Pol_like, LigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for non-homologous end joining (NHEJ)-mediated repair of DNA double-strand breaks (DSB). NHEJ-mediated DNA DSB repair is error-prone. PaeLigD is monomeric, containing an N-terminal phosphoesterase module, a central polymerase (Pol) domain, and a C-terminal ATP-dependent ligase domain. Mycobacterium tuberculosis (Mt)LigD, also found in this group, is monomeric and contains the same modules but these are arranged differently: an N-terminal Pol domain, a central phosphoesterase module, and a C-terminal ligase domain. It has been suggested that LigD Pol contributes to NHEJ-mediated DNA DSB repair in vivo, by filling in short 5'-overhangs with ribonucleotides; the filled in termini would then be sealed by the associated LigD ligase domain, resulting in short stretches of RNA incorporated into the genomic DNA. The PaeLigD Pol domain in vitro, in a manganese-dependent fashion, catalyzes templated extensions of 5'-overhang duplex DNA, and nontemplated single-nucleotide additions to blunt-end duplex DNA; it preferentially adds single ribonucleotides at blunt DNA ends. PaeLigD Pol adds a correctly paired rNTP to the DNA primer termini more rapidly than it does a correctly paired dNTP; it has higher infidelity as an RNA polymerase than it does as a DNA polymerase, which is in keeping with the mutagenic property of NHEJ-mediated DNA DSB repair. The MtLigD Pol domain similarly is stimulated by manganese, is error-prone, and prefers adding rNTPs to dNTPs in vitro. The MtLigD Pol domain has been shown to prefer DNA gapped substrates containing a 5'-phosphate group at the gap.	1.24989e-105

Protein sequences

>NC_017186.1|WP_013227034.1|5779685_5780651_-|TIGR03557-family-F420-dependent-LLM-class-oxidoreductase
MRIGYTLMTEQTGPDDLVRFAAGAERAGFDFEVMSDHYSPWLDEQGHAPYAWAVLGAVTQVTERAELMTYVTCPTMRYHPAVVAQKAATVQALSGGRFTLGLGAGENLNEHVIGRGWPPANVRHEMLAEAVQIIGGLFDGGYFDYEGKHFRVDSAKLWDLPRTRVPIGVAVSGSQSVQRFAPVADVMIAVEPKVELSQEWDATKLGGAPSRKVGQLPVSWGTDRDAAVKRAHEQFRWFAGGWKVNAELPGPAGFAGATQFVREDDVAGSIPCGPDAEPIVEAVREFEKAGFTDVALVQIGGDQQEGFLDFAEKELLPALRG
>NC_017186.1|WP_013227033.1|5779289_5779655_+|STAS-domain-containing-protein
MNLPRARHPNLRLRTAWPAPHAVLVTARGELDSATAADLATLLSDRLWATPEQLVVDLSEVDFLGVAGVRVLLHAALQAGQGGTGLLVVTGANAVVRRALRVTGADRRLALADRRPAPAPA
>NC_017186.1|WP_013227032.1|5778267_5778996_-|GAF-and-ANTAR-domain-containing-protein
MTGGHEQLTARLDEVTLAMESLTGMLDSELDLGQMLQAVCDHAVQVVPGADMASITLVREGVPETVASTDQRAVNFDREQYRIGDGPCLRAAETGQPVRVGVGAVGDLWPQFVTSAEQLGVASFLAAPLTVDEDMSGAVNLFGFGEHGFSELGTKILELYTATVVIGLRSARRYFAARELVDQLNRALETRAVIDQAKGILMAAHRITAEEAFQRLVKRSQDGNRKLHEVAAEFVAAVATTT
>NC_017186.1|WP_013227031.1|5778012_5778225_+|hypothetical-protein
MGTQIRISREDGSLPCEICGFPTMHVAQVVADDGTVLGRTLVCTTCQRSKHRPEPAPVESEAPPDEVPAG
>NC_017186.1|WP_013227030.1|5777635_5777833_-|hypothetical-protein
MRDKRNDLRPVADLLVDGGDAAELERTRHKAALAVAARAKDPEDCARLLDMLGLHRTGRRSTDVA
>NC_017186.1|WP_013227029.1|5776686_5777619_-|Ku-protein
MARPVWSGALSLGLVTVPVELYPAVADHTIHFHQFERGTADRIRNRRVNERTGEEVTQGEIVKGYDLGGGDHVLVEPDELDEIAPERSRRIDIEQFVELDEIDPWFFDKTYWLKPAKEDFAKAYGLLLQAMDRSEKAGVAKFVLRGKEYLAAVRAGEGVMVLNTLHFVADLRKPKDVMGKLPEVPKPRPKELDMALALVDEMTAPWKPEDYRDEYSQRVEELIKAKEAGKEIAHEEEPEPSADVVDLFEALSRSVKNRKSGGKEPKKKAAKKPELAELSKSDLDKLAREQGVKGRSKMTRAQLEKALKAS
>NC_017186.1|WP_013227028.1|5775745_5776690_-|non-homologous-end-joining-DNA-ligase
MTGPGWREPTLATLTDRRFSDEDWIFERKLDGVRAICVRDSGTPTLYSRNHKVMDNAYPEIVEALAAQGGPRFVADGEIVAFDGANTSFAALQPRIHVSDPDRARATGVRVYYYLFDLLYLDDRDTTALPLRQRKALLREAFGFADPLRLSAHRNTEGEKFFEEACRRGWEGVIAKRADAPYHHGRSPDWLKFKCAQGQEFVIGGFTDPQGARHGFGALLLGYHDDDGLRYAGKVGTGFDERLLTSLHARLRDRETARSPFAGPVKEPGAHWVRPELVAQIGFSEWTRDGRLRHPRFAGLREDKKAADVVRERA
>NC_017186.1|WP_013227027.1|5774885_5775749_-|non-homologous-end-joining-DNA-ligase
MKTSHPDKVFYPEDGLTKGDVVEYYRAVADVMLPHLRGRPLTLRRFPDGIGKPGWFQKHPGEHFPDSIRVERVPRRGGGTDEYVVCEDAATLEYLANQGTVEFHVWLSTADAPERPDRLVLDLDPPDGTPVTELRTVARRIRDHYERVGLTAFVQATGGRGFHVLAPLDAKSETDVVLELSRALADRVAGDDPDRLTTAQRKDQRGDRIFLDANRNGYAQTFVAPYSLRARPGAAAATPLDWRELGTADPAGWSLVKEKRRLARKEDPWRDLDEHAGSAEAALKQLG
>NC_017186.1|WP_013227026.1|5774242_5774875_+|UdgX-family-uracil-DNA-binding-protein
MPDSRGAEPPDTTDLDRLRSAASGCQACPLYQDATQTVFGEGTARAKVLVVGEQPGDKEDLAGEPFVGPAGKLLDRAFEEAGFDRRSLYVTNAVKHFKFKRDERGKRRIHQKPGRTEVVACRPWLLAELRSVRPELVLLLGATAAQSLLGPKFRLTAHRGEPLEPPEELAGLVPAAMATVHPSAVLRAPDRDEAYASFVADLQAAAKLLG
>NC_017186.1|WP_013227025.1|5773734_5774151_-|CBS-domain-containing-protein
MTTARDIMTSDATCARESDTVHDAAVTMARKGVGALPICGEDNRLKGMITDRDIVVKVLAEGKDPRAVHVGELAQGEVVTIGADDDAQEILRTMSEHRVRRLPVIDGHDLVGIVAQADVARALSNPSAGELVEALSYD
>NC_017186.1|WP_013227035.1|5780894_5781224_+|hypothetical-protein
MPQSWSGKRERQYEHIKDSAEDRGASTKRATEIAARTVNKNRAQSGESRQASKTSLKDKSPQQRGGERSGNRKGPGGPTKEQLYNEAKKKNIDGRSKMTKKELERALGR
>NC_017186.1|WP_013227036.1|5781286_5781736_+|anti-sigma-factor
MEEPRSDSSFGGKQSVDELLDELVELRLPAMAEQIPLVRMLTHGVVSRADFGLDAIADAKMAVDEACAQLVQLAELGSQLQCRFRLAPDGLHVIVSTRSSDPRPPSDRTFGWHVLTTLSRSVTAHCDALPGGGAGIVTIELVLNPGTSA
>NC_017186.1|WP_013227037.1|5781732_5782524_+|SigB/SigF/SigG-family-RNA-polymerase-sigma-factor
MSSERKTLLHRPDEYAHCEPLFQELGSLDTADPRRDVVRSKLVTELLPLAEHIATRFSGRGEPREDLVQVARIGLINAVDRFDPARGHDFLSFAVPTIMGEVRRHFRDTGWSVRVPRRLKELHLSLSQGSAVLSQRLGRAPTPTELAEHLNLDVDEVREGLLAGNAYQALSVDKPVHDDAEALSLADTMGEPDHEMAMVENHEALQPLLQELPKRERAILVMRFFGGLTQTQIADRVGISQMHVSRLLSQTLEQLRGKLTGEG
>NC_017186.1|WP_013227038.1|5782555_5784073_-|CYTH-and-CHAD-domain-containing-protein
MAAPSQVTERERKYEIVAGSGVPRLVGVGGVETQDDPVEHVLDASYYDTETFRLARSGITLRRRVGGPDAGWHLKLPVSADERQELQLPLGGDPHKVPGRLRRLVRAYTLGEKLVPIAHLRTDRFAHRLADAGGRTIATLTDDHVTGEAGGATARFDEWRELELELDPAAEPALLGEFDHALTEAGASVSPWPSKLRRLVGDRVSAPPRPGKKPSAGDVVLAALREHYGRLRRADVGVRLDAEDSVHQMRVAIRKLRSTLRTFGSLIDEKETASVTTELQWLGRELSPARDTEVTEERLREQLDEVPSELVFGPLRQFLTRHFAREAEVGRARALAALTGKRYLQLLRKLDTLLEEPPLTAKARKPAKAGLRKPLRKAAKKLSRAEAAARGLTGVELETALHDVRKKAKRARYAADTVKPVYGKKLAKWRKNVKAVQGTLGEHQDTVVGREILHHLAIAGHGEGQNTFTFGMLHAQDAGRAAKLRETFAREWRRLRKGGRPGWLG
>NC_017186.1|WP_013227039.1|5784197_5784719_+|hemerythrin-domain-containing-protein
MNGNQSATDLTTVLAGDHRELDRLCTELELGQGSPENRKDLADHLIAELVRHSVAEEPYLDGDGDLAEADRLMRQLEGAGPQETRFERLLGGLIRAVRRHVREEGPAAVREIGRTCSADRQAELGREVLETREAAPTLPHPDLADRVPQADQLWPGPGFVDRARAALRAPASG
>NC_017186.1|WP_013227040.1|5784760_5785561_+|GAF-and-ANTAR-domain-containing-protein
MSVGEEEWARERAWFGRDGEPEPGPLARQFADLTRTLLDVTPTVAGVLKLVVGAATALIPDAHLVSVTLRDADGTFHTPVGTAPIAEQLDQVQYDHGEGPCVESARPDGPAVGWSQDLGRDPRWPAFGPAAARHGFHSVLATALLPDARPPRLSGALNIYSRTPGAFDARAIDLALLLATHASLALAHTQAVAAAELESAHLRRAVDSRDVIGQAKGILMQRRGITADEAFDVLRRASQDLNVKLADLAKALAARHTEVDLPASEA
>NC_017186.1|WP_013227041.1|5785639_5786113_-|hypothetical-protein
MTTNAYLSFLAIGVALIVIDGQIIYRSGRRYLENSYGDPAAGASMTRLVTVLFHLATLGVLALISTIDMGGSDLPGVVGRIGVLLLILALAHAITLGVLARIRGEQEVEAVVQRGPRPRVDAAEQQQAATVTPVPGQDGRYPAASPTLENRSPYSAQ
>NC_017186.1|WP_013227042.1|5786277_5786742_-|SRPBCC-family-protein
MSTITEIVDVEVPVSTAYNQWTQFEEFPRFMEGVEEIRQVDATHTHWVTRFGGVTREFDATITEQHPDERVAWTSDSGPDHAGVITFHRLDDSHTRVTAQMDIDPEGFAENVADKLGVLGRRVKGDLKRFKEFIEQRGGRETGAWRGDVDRPGR
>NC_017186.1|WP_013227043.1|5786877_5787291_+|phage-holin-family-protein
MIEEVNKKPASDRSVGELVTDLTDEVKRLVRDEMRLAAFELQRKGKKMGLGAGLFGAAGLFAFLGAGTLVAAAVLALALVVPGWLAAVLVAVALFLVAGIAALVGKKEVTQGVPPVPEEAISGVREDVATVKQGVRT
>NC_017186.1|WP_013227044.1|5787287_5787593_+|DUF3618-domain-containing-protein
MSGDFPKNAEEARLDRDATREELTETLEALGQKLDVKARVKENVDEKLDQATAKVADVTNEPTAVKFRQGADAVRANPLPVFAGVLGLLILIRLILRRRNS

Crispr_ID: NC_017186_19

• CRISPR_ID: NC_017186_19
• CRISPR_location: 6436780-6437778
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 16 spacers
• Cas_protein_info: cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NC_017186_19

Consensus_repeat	Method
GTTGTCCCCGCACGCGCGGGGCTGGTCCC	CRISPRCasFinder
TCCCCGCGCACGCGGGGCTGGTCC	CRT
CGCACGCGGGGCTGGTCC	PILER-CR

spacers of NC_017186_19

>19.1|6436809|30|NC_017186|CRISPRCasFinder
GTCGTGTAGCGGGTGTCGTCGTCGTTGGGG
>19.2|6436868|31|NC_017186|CRISPRCasFinder
TGCCCGTGGCGGAACCTGATCGTCACCAAGC
>19.3|6436928|32|NC_017186|CRISPRCasFinder
GCGCCTTCGTCCCAGCTGGCCGGCTCGACGAT
>19.4|6436989|29|NC_017186|CRISPRCasFinder
AGGGAGATCGACACGTCGGACAGCGTTTC
>19.5|6437047|31|NC_017186|CRISPRCasFinder
GGAAGCCGGTTGAGCTTCGCGCCGCACCGTC
>19.6|6437107|30|NC_017186|CRISPRCasFinder
CAGGCCGACTACGAGAAGCAGAGCCCGCAG
>19.7|6437166|32|NC_017186|CRISPRCasFinder
ATCCCGCAGTAGCGACAGGTGTCGCCGTCGCG
>19.8|6437227|32|NC_017186|CRISPRCasFinder
CACACGATCGGCGGTTTCACCCGACCTTCGCG
>19.9|6437288|32|NC_017186|CRISPRCasFinder
GCATTGGCTAGATTGTTCTGGAAAGTCTGATC
>19.10|6437349|32|NC_017186|CRISPRCasFinder
GTCTCGAACGTCGTGGGCGAGACGACGTGCTC
>19.11|6437410|32|NC_017186|CRISPRCasFinder
GACTTCAAGCTGCGCCTGGTCACCCTCGGCGT
>19.12|6437471|32|NC_017186|CRISPRCasFinder
CCGTTCGGGTCGCACTCGTACGTGGGCAGATC
>19.13|6437532|34|NC_017186|CRISPRCasFinder
CCGTCACCTGCCCGCCGGGCTACACCAGCCTGTT
>19.14|6437595|33|NC_017186|CRISPRCasFinder
GACGGCGTCAAGAACTGGTACGACGAAGTGGCA
>19.15|6437657|32|NC_017186|CRISPRCasFinder
TACGTGTACGTTGGCGCCTACGGAACAGGAAC
>19.16|6437718|31|NC_017186|CRISPRCasFinder
GCTCGGGCAGCTCAACCTCGCCACTGTCTAC
>19.17|6436808|35|NC_017186|CRT
TGTCGTGTAGCGGGTGTCGTCGTCGTTGGGGACGT
>19.18|6436867|36|NC_017186|CRT
CTGCCCGTGGCGGAACCTGATCGTCACCAAGCCGCT
>19.19|6436927|37|NC_017186|CRT
CGCGCCTTCGTCCCAGCTGGCCGGCTCGACGATATTT
>19.20|6436988|34|NC_017186|CRT
CAGGGAGATCGACACGTCGGACAGCGTTTCGCGG
>19.21|6437046|36|NC_017186|CRT
CGGAAGCCGGTTGAGCTTCGCGCCGCACCGTCCGTT
>19.22|6437106|35|NC_017186|CRT
GCAGGCCGACTACGAGAAGCAGAGCCCGCAGGAGC
>19.23|6437165|37|NC_017186|CRT
GATCCCGCAGTAGCGACAGGTGTCGCCGTCGCGGTTT
>19.24|6437226|37|NC_017186|CRT
GCACACGATCGGCGGTTTCACCCGACCTTCGCGGTCG
>19.25|6437287|37|NC_017186|CRT
CGCATTGGCTAGATTGTTCTGGAAAGTCTGATCGTTG
>19.26|6437348|37|NC_017186|CRT
CGTCTCGAACGTCGTGGGCGAGACGACGTGCTCGTTG
>19.27|6437409|37|NC_017186|CRT
CGACTTCAAGCTGCGCCTGGTCACCCTCGGCGTGTCG
>19.28|6437470|37|NC_017186|CRT
GCCGTTCGGGTCGCACTCGTACGTGGGCAGATCGTCG
>19.29|6437531|39|NC_017186|CRT
CCCGTCACCTGCCCGCCGGGCTACACCAGCCTGTTGTCG
>19.30|6437594|38|NC_017186|CRT
GGACGGCGTCAAGAACTGGTACGACGAAGTGGCAGTCG
>19.31|6437656|37|NC_017186|CRT
CTACGTGTACGTTGGCGCCTACGGAACAGGAACGTCG
>19.32|6437717|36|NC_017186|CRT
CGCTCGGGCAGCTCAACCTCGCCACTGTCTACCTTG
>19.33|6436867|42|NC_017186|PILER-CR
CTGCCCGTGGCGGAACCTGATCGTCACCAAGCCGCTTCCCAT
>19.34|6436927|43|NC_017186|PILER-CR
CGCGCCTTCGTCCCAGCTGGCCGGCTCGACGATATTTTCCCCG
>19.35|6436988|40|NC_017186|PILER-CR
CAGGGAGATCGACACGTCGGACAGCGTTTCGCGGTTCCCG
>19.36|6437046|42|NC_017186|PILER-CR
CGGAAGCCGGTTGAGCTTCGCGCCGCACCGTCCGTTTGCCCG

CRISPR arrays and Neighbor proteins around NC_017186_19

CRISPR arrays

The CRISPR arrays of NC_017186_19

>merge|NC_017186|19|6436780-6437778|CRISPRCasFinder,CRT,PILER-CR
GGTTTCCCCGCGAACCCGGGGCTGGTCCTGTCGTGTAGCGGGTGTCGTCGTCGTTGGGGACGTTTTCCCCGCACGCGGGGCTGGTCCCTGCCCGTGGCGGAACCTGATCGTCACCAAGCCGCTTCCCATCGCACGCGGGGCTGGTGCCGCGCCTTCGTCCCAGCTGGCCGGCTCGACGATATTTTCCCCGCGCACGCGGGGCGGGTCCCAGGGAGATCGACACGTCGGACAGCGTTTCGCGGTTCCCGCGCACGCGGGGCTGGTCCCGGAAGCCGGTTGAGCTTCGCGCCGCACCGTCCGTTTGCCCGCGCACGCGGGGCCGGTCCGCAGGCCGACTACGAGAAGCAGAGCCCGCAGGAGCTCCCCGTGCACGCGGGGTTGGTCCGATCCCGCAGTAGCGACAGGTGTCGCCGTCGCGGTTTTCCCCGCACGCACGGGGCTGGTCCGCACACGATCGGCGGTTTCACCCGACCTTCGCGGTCGTCCCCGCGCACGCGGGGCTGATCCCGCATTGGCTAGATTGTTCTGGAAAGTCTGATCGTTGTCCCCGCGCACGCTGGGCTGATCCCGTCTCGAACGTCGTGGGCGAGACGACGTGCTCGTTGTCCCCGCGCACGCGGGGTTGGTCCCGACTTCAAGCTGCGCCTGGTCACCCTCGGCGTGTCGTCCCCGCGAACGCGGGGCTGGTCCGCCGTTCGGGTCGCACTCGTACGTGGGCAGATCGTCGTCCCCGCGCACGCGGGGCTTGGGTCCCGTCACCTGCCCGCCGGGCTACACCAGCCTGTTGTCGTCCCCGCGCACACGAGGCTGGTCCGGACGGCGTCAAGAACTGGTACGACGAAGTGGCAGTCGTCCCTGCACACGCGGGGCTGGTCCCTACGTGTACGTTGGCGCCTACGGAACAGGAACGTCGTCCCCGCGCACGCGGGGCTGGTCCCGCTCGGGCAGCTCAACCTCGCCACTGTCTACCTTGTTCCCACGCACGCGGGGCTGGTCCCT

>NC_017186|19|18|6436780-6437778|CRISPRCasFinder
GGTTTCCCCGCGAACCCGGGGCTGGTCCT	GTCGTGTAGCGGGTGTCGTCGTCGTTGGGG
ACGTTTTCCCCGCACGCGGGGCTGGTCCC	TGCCCGTGGCGGAACCTGATCGTCACCAAGC
CGCTTCCCATCGCACGCGGGGCTGGTGCC	GCGCCTTCGTCCCAGCTGGCCGGCTCGACGAT
ATTTTCCCCGCGCACGCGGGGCGGGTCCC	AGGGAGATCGACACGTCGGACAGCGTTTC
GCGGTTCCCGCGCACGCGGGGCTGGTCCC	GGAAGCCGGTTGAGCTTCGCGCCGCACCGTC
CGTTTGCCCGCGCACGCGGGGCCGGTCCG	CAGGCCGACTACGAGAAGCAGAGCCCGCAG
GAGCTCCCCGTGCACGCGGGGTTGGTCCG	ATCCCGCAGTAGCGACAGGTGTCGCCGTCGCG
GTTTTCCCCGCACGCACGGGGCTGGTCCG	CACACGATCGGCGGTTTCACCCGACCTTCGCG
GTCGTCCCCGCGCACGCGGGGCTGATCCC	GCATTGGCTAGATTGTTCTGGAAAGTCTGATC
GTTGTCCCCGCGCACGCTGGGCTGATCCC	GTCTCGAACGTCGTGGGCGAGACGACGTGCTC
GTTGTCCCCGCGCACGCGGGGTTGGTCCC	GACTTCAAGCTGCGCCTGGTCACCCTCGGCGT
GTCGTCCCCGCGAACGCGGGGCTGGTCCG	CCGTTCGGGTCGCACTCGTACGTGGGCAGATC
GTCGTCCCCGCGCACGCGGGGCTTGGGTC	CCGTCACCTGCCCGCCGGGCTACACCAGCCTGTT
GTCGTCCCCGCGCACACGAGGCTGGTCCG	GACGGCGTCAAGAACTGGTACGACGAAGTGGCA
GTCGTCCCTGCACACGCGGGGCTGGTCCC	TACGTGTACGTTGGCGCCTACGGAACAGGAAC
GTCGTCCCCGCGCACGCGGGGCTGGTCCC	GCTCGGGCAGCTCAACCTCGCCACTGTCTAC
CTTGTTCCCACGCACGCGGGGCTGGTCCCT

>NC_017186|19|3|6436784-6437776|CRT
TCCCCGCGAACCCGGGGCTGGTCC	TGTCGTGTAGCGGGTGTCGTCGTCGTTGGGGACGT
TTTCCCCGCACGCGGGGCTGGTCC	CTGCCCGTGGCGGAACCTGATCGTCACCAAGCCGCT
TCCCATCGCACGCGGGGCTGGTGC	CGCGCCTTCGTCCCAGCTGGCCGGCTCGACGATATTT
TCCCCGCGCACGCGGGGCGGGTCC	CAGGGAGATCGACACGTCGGACAGCGTTTCGCGG
TTCCCGCGCACGCGGGGCTGGTCC	CGGAAGCCGGTTGAGCTTCGCGCCGCACCGTCCGTT
TGCCCGCGCACGCGGGGCCGGTCC	GCAGGCCGACTACGAGAAGCAGAGCCCGCAGGAGC
TCCCCGTGCACGCGGGGTTGGTCC	GATCCCGCAGTAGCGACAGGTGTCGCCGTCGCGGTTT
TCCCCGCACGCACGGGGCTGGTCC	GCACACGATCGGCGGTTTCACCCGACCTTCGCGGTCG
TCCCCGCGCACGCGGGGCTGATCC	CGCATTGGCTAGATTGTTCTGGAAAGTCTGATCGTTG
TCCCCGCGCACGCTGGGCTGATCC	CGTCTCGAACGTCGTGGGCGAGACGACGTGCTCGTTG
TCCCCGCGCACGCGGGGTTGGTCC	CGACTTCAAGCTGCGCCTGGTCACCCTCGGCGTGTCG
TCCCCGCGAACGCGGGGCTGGTCC	GCCGTTCGGGTCGCACTCGTACGTGGGCAGATCGTCG
TCCCCGCGCACGCGGGGCTTGGGT	CCCGTCACCTGCCCGCCGGGCTACACCAGCCTGTTGTCG
TCCCCGCGCACACGAGGCTGGTCC	GGACGGCGTCAAGAACTGGTACGACGAAGTGGCAGTCG
TCCCTGCACACGCGGGGCTGGTCC	CTACGTGTACGTTGGCGCCTACGGAACAGGAACGTCG
TCCCCGCGCACGCGGGGCTGGTCC	CGCTCGGGCAGCTCAACCTCGCCACTGTCTACCTTG
TTCCCACGCACGCGGGGCTGGTCC

>NC_017186|19|2|6436849-6437105|PILER-CR
CGCACGCGGGGCTGGTCC	CTGCCCGTGGCGGAACCTGATCGTCACCAAGCCGCTTCCCAT
CGCACGCGGGGCTGGTGC	CGCGCCTTCGTCCCAGCTGGCCGGCTCGACGATATTTTCCCCG
CGCACGCGGGGCGGGTCC	CAGGGAGATCGACACGTCGGACAGCGTTTCGCGGTTCCCG
CGCACGCGGGGCTGGTCC	CGGAAGCCGGTTGAGCTTCGCGCCGCACCGTCCGTTTGCCCG
CGCACGCGGGGCCGGTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NC_017186.1|WP_013227602.1|6421783_6422272_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	unknown	unknown	gnl|CDD|375821
NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|379021
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|378243
NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|379274

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.9e-55	182.0	0.0
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	1.5e-46	153.2	0.3
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	3e-31	103.3	3.9
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.9e-59	195.7	0.0
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	2.3e-96	318.3	3.8
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	5e-111	366.4	1.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.80328e-21
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.75313e-78
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.02918e-12
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	7.65375e-42
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	gnl|CDD|375821	pfam18395, Cas3_C, Cas3 C-terminal domain. This is the C-temrinal domain of Cas3 proteins. The C-terminal domain (CTD) is shown to completely wrap ssDNA inside the helicase. Deletion of the CTD (aa 819-924) reduced CRISPR interference. It is suggested that the CTD regulates the N-terminal HD nuclease activity by functioning as a substrate filter.	5.47198e-09
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	0.00914745
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	gnl|CDD|379021	pfam13020, DUF3883, Domain of unknown function (DUF3883). This is a domain is uncharacterized. It is found on restriction endonucleases.	1.15745e-05
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.44632e-24
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	gnl|CDD|379274	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies).	1.9456e-07
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.53205e-80
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	9.17843e-107
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	9.95055e-141

Protein sequences

>NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein
MIEEPVELAKDLTRLVLQQADSVVAMYLAGAKYEQPVTREQKESIESIIAADYDGRTVVELLQNGHDAHDSGRSDGKLEFLLDENEGAHGVLYAANGGRPLDQENFRSMCLIARSSKRPDEGIGNKGVGFKSVLQLSDCPEVYSARHEGAGRFDGFRFRFGRPDDFDGLAARSKENWPGLADELRENVSTLKITVPLFETPTVVEDFARRGYSTVVRLPLRSASTRDHARDQLEELAHDEVPFHLFLTRVAEIVVRSQAGETESRRRLTRSTRARRGTSTLSVEHIDLGEQREYVILKRVVAETGIRAAIRASLDDNAIGSGWAGWQGAAEVSVAVPLGAALSQGRVYTFLPLGPGSPCPIAALVNGPFFTRLDRRDVHESIPLNDFLFAEIAALCADAVVAACRGDLELPDEVPLDLVCWAPGWTQRLIAALQALGVELVDLPVLPPLQHQGEGLTFKSALLWSYRGAVFTPEAVTAAGETRLIRYSIDEQRLRRLRKLAKATDHPVEARPADLAGFAETLADDLLRRGESYEVWAGFYDDLSVVLTDVTLIRGHRVFLTEGGILRTSIEDDDLMIYFGPVRGEAGELPELPEVVRDRLAFMPADINWSDERGQRPGRRWLEAIVREYRTDAVLDLIGKVMYDTEAEEVRSACLRFAFDLWQDTPAERRATALGRAGLLVRTRSGWKAPAEAYFDAGWGGPAGKIDRQLADLVKATALISGTLAAVGQSLLFKPELGEATLDDVRTFFEALGVRHGLVPLTVRASRFQLQGKTLKNPRTVPVFPIEISVATQAAWRELAARHSGKPSYDSTRYQPAGGIAYLPGQEEWSEFDDTARRLYFQLVLHGLEVWPATTLWTYFQASSDSVRVTWPTFVAAFLVRADWIPQTTPGDRGKQFFRPMSDAWWVGNTDTPDYLSADPAAFRSLLTDRVRVHLQRLGARFWDDPGTAADRLRELTSVVRLRGPRMSLVRNAYEQAWRDLADRGEEVPHEVIVSVHGSLGVLDLDQEGPAVYTLDEDGAVQAALLIQTPLPMLAVRSPGVAERVRQTLVSDGVSRLRAASAATVQVLADGTDPLTMKSQPLTDLGGDWLPLLVDAIADRRRQALPAAGITVGATAGALRDSVGLVLADSITAVIDGHPVDQEFAPSSMRVVSPEGDPVIVALRGTGEPWVVLQSAAAALAEFRGGPPIADSVRLALIDLTQRCGDRTPTLDDLAVVLKLPVTELQSLAGDAASTRFEVTPVLGLLACLDPGIAEELQGDRIGDQQEMLDWLSRRGFDADEILALAGQNDLLDATRQLDIPLAQANAGLRAVNLPLLHNDIGHRQQFDAYLQRHRPELQDQLRDRFVARFRRGEPLDEYLRLRDLPGLEPDSTWLDTYWHLPDHVVQARLDLWLASVGEPLAGKDRLPPVDELRDRGRRAVMRTLERARIVIEAWLQRNTAGTGARPAEIAGTLEKMVQTGFLDFEVPRTSAVVVWLGEHGQWPVGMPATTEPRQLDLTDGDLKAAESRLNAGHDTAKRRTETVRYAGKTYSTGTEDRDSLIRAVRESVPQGVLDTSATADRMAPLPPSSSAVSGSSSGEWRAPVLSAEKTRLIGLAGEIVAGEWLNAKFGLQPEDTWVSGYRAEYLADGKGNDSCGYDFLVTLPDRTLLYEVKATTDNARQFTLGESEVRRANALRPHEEYHILFISNVLDPDKMRLRVLPNPFSVGGLASYQVVGRSLNLRFRSAD
>NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein
MMTKHPSNSDLPHEGDLNHGEERDRLTRPAVRPIPKWVVVTGVPLMMVIAISAAWLLLSTGATRDQLDALRTAGTLGVGFGGVVALWLAVRRQRSTEHDLLQKYQAHELAERVAAQNQAAADRAAAHAEHDARERRLTDLYLKAVEHLGSAHAPVRHGGLYALERVAQDNPSQRQTVVDVVCAYLRAPYTPPNTSRASRLGLKRPLQSSTRSRATNSARARETTTTSAHTRTISASLEEREVRMTAQRLLKRHLSLDIHDNSTGLFWDNIDLDLAGATLVSFDFRGCRVKHCTFLHSTFVGPARFDNAVFTGEASFARSAFTAEARFSGATFANETWFKGATFTDGPIFNGTTFSGEYFFQEVNFAGNAQFDGTLFTEGTPVEVSAHLDGQSRSASP
>NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein
MAFPNRWTASSSAAAALANSPTRRIREVQRIEQGMGRGVRDSDDHCAVLLVGSKLAMATRDPDWKKLFSPATRAQLDLSNQVAVQLKGQGLDAVRSALTACLDRDPNWVERSRRALAEIRYLDAGTIRPEAIAIRAAFDLASAGQYSAAADEIQRAINGIEDTLLRTEGQLPAPRHPPSSPSSSKASPSRRTERCSSRWSE
>NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase
MDDVEKWCPEPLWLLAQPLLPEAPQRHQGGGRRRLDDRVVLAAILYVLQTGCAWSALPASFGVSAPTAHRRFTEWVETEVFARLHQAVLDLLGSAGAIDWSRASVDGMHVRAVKGGDLTGPSPVDRGKRGSKIHAISDRSGLPLAVGVSAANRNDHLELEAVVDAVVPVKGPAGRPRRRPRKLHADKGYDYPTCRKALRRRGIIARIARRGIESPKRLGRHRYVIERTLEWVSRFRRLARRYERKAAHFTAFTQLACAVICYRRAIKLDLLTHNNPK
>NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein
MLGINATLADIEWDEDRTPQAEAAWERLGSHLGFTSTRPEKLYGKGPDNLWALAGDRHAVVEMKTGCTTDMIAKKDVDQLGGSVRWDQDNHPGITSIPGITSIPIMVHPSRIVNHQGTPVPGMRVITAAKLDELKTAVRSFAVALADGQGRWYDEQGVSVQLTQARLTAGKFLNAFTEVNLVES
>NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein
MSPRERDAHELRQLARETADQLASFAHIFSAADRRNDRVTPPELFTLAGLLEDAAAVLGEDARVKPLIFSFKDTIVPQKELNFDIAYRYLTPIVRAIRSRYNLPGSPHASPASKPRRRVDVRIDTDRHDRAQSDGDRDSGT
>NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein
MSLTDEQWDALGLDRVVVRDRAEFFIGYAGSEAPLFDVDGVIDAFRDGPLGDETDQKVAKFTDTDDAGPAGLLRRRMAEAAGRPGRRPWARTAERADALRHAAQAALLGDTREGRNLLLQSASLYRELGLPFGDFLSAAAVGPGDAAFEAAGQLRSIIFGSETAPEARRVDEGYFSLPRRLLAPAQQIAVLFTALSSADGVDGFGIGIDLLRRASQATQATSVGVTGRPVALWWECGVRLAELTYGRPSARDDLRTTIAELATAHGQALRTAQFDRYHWPRALSKMDLVDLDLTGLTAISNRVLRQLGEPEWSMFEDFRDLTPLSQVSVQVGIRLSGPGRPRTPASGPSPSPEPTPGPAAASDYVPESRSPSLWARS
>NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein
MIVQWCCKGMAKLPEREAERILTGGTGIRCRSWLTVAPKPFPLGKNLDRLTEDNLDRHVNKYSDPDPVTGAPFHDVTPFISLSAGCVDRQVAIERNETHSALRTALTFATTDYSQPGPNWPRCAGWVFYCYVLTGVNRAVSIPSVAEEYRELNLGRSYSRWQPQGEVMAKINVPSRQILCAVHWTPLPSGESKWDEVLWNLRFTHPAALLGERNML
>NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein
MEIAKLIVAALTPLSVALIGVVLTRSMRRLEHSNWLNQKLIEKRIEVLGEALPKLNDLYCYFSWIGTWASLSPVDVLQRKRDLDRLFHANRAFFTSSAFDVYGAFIDLLFETYAQPGKGARLRTEMTSHNGNRADVYPKKWEEGWSEMFSGVPRTSSLLTVKKCYEGLVMTFSAEVGIERSDAVGR
>NC_017186.1|WP_013227602.1|6421783_6422272_+|hypothetical-protein
MEAARDDLSHVSVPDLLGRYAAILQELQDRGVVRTRNAPLGDYAEYLAAQVYDGELAANSLKSYDLLAADGRRIQVKARTVAPDTRAGAVFSVFHSFEFDIAVLITFDSATYALRQAREVPAADLETAGRHSDHVNGRLIRITAGIRLGVDVTARFRAVASR
>NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase
MDRGTEAWLRSLTFDRVGVRLAFEEAFDAVLATRAQRARLDAAITELAAPPVFAPVMGRLACLHGVSTLTAFGLVTEIGDWRRFTGASIGAYVSLVPADSSSGEHRHQGAITKTGNSDGQRLLVEAA
>NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease
MRKTVRVLPDMDRWRQLISEYGQLQQLTGHTPQTRGQRFNNMIAELLQCWGIQATANVRAAGEIDVAFAIDGVRFVVEAKWEKTKADTGRIAKLQKRVRQRLSGTYGVFLSMSGYSPEALDDIADGDRLEVLLLSIEHWEAMLGGLVPPQELFNLVRDRASFYGEPYTPLAQLFAPAEIPDIRLGPPSEMTDGPLLEAVDGLDAQVVLSGIESGQLGIACHGQNSLLVTTEHGILDVDFEAHTVTMAAPVPDCQRNVLANEDGSIVFLRRSGVGLFRDGQITTVGGGLSGNSCLCRHPDGSLWVFDNGGLLDHSASVTRLDDKLGLQKRHKINYSPANAFTSA
>NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein
MLRLFDAPVYRDWLFWFMLAWAALDFVSVLTLGPPSGLPRWLTALIGAAFFALVCGLVPAWIRLRLRRRRHGHGRMATKER
>NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MFLSKLTINVHSRTFRRDYANVHDMHRTLMSVYPDVPADTPKRQAHGVLWRLDSNRGSYVQYVQSHTRPDWDKLPDGHLNAPAEIRPLQPVLDAITAGRKLAFRFVANPTRCDNKTRQRIPLRQPADQIDWLIRQGQTHGFVIPATAAGPDIAITPTATITGRKSEPSKITIEPVRFDGHLIVTDPAAFTDAFSNGIGRAKAYGCGLISLAPSRTL
>NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTHTLALCFDAPMQSWGLRSRGILRDTAREPTKSGVVGLLAAATGVERDDEAGIATLAALRLGVRVDREGLLERDYHTTQNVPTTTGSGHRTVVSERYYLADALFLVAIEGPETLLSELADAVTNPRWPLFFGRRAFVSARPLFDDGLHAGNLEQILREHRWLEHPDRAGAMIPGQQQIALRTVVDCPTGTVGAEPRHDVPRSFAHGARSFATRTVLVGEVPLTDNMIPAGDTTCS
>NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MIIELHLLQSFPVSNLNRDDVGQPKTATFGGSTRGRISSQCLKRSARQLFTDHGLTDTETGIRTKRLRNEAAALLTKRGRDEQEAAGVVTAGLEQLGFGVDQDKGLTEYLLFVGTTAIEHLAGYCDDRWDTLAAVAAAKDGKKKPAKAKPDKNDLAEAKRMLDATRVADVALFGRMIADNKDFNVDAASQVAHALSTHAVATEFDYYTAVDDLKPEAESGADMIGTVDFNAACYYRYANLDLDRLRQNLAGDDELVARAARAWLGAFIHAVPSGKQNSMAARTMPDTLLGVVRDGGAWNLANAFLKPVTGEDIMAASTASLTQHFQQLRAFYGSSSIRAAVAASVTGQLPDMDGTDTAASIDEFTSRILAAGTTPA
>NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSTPVAQRRDGFISALYALNAGLESSIPKRRSEARQVLARLRRSLVTARPEPAAYEVVFRHDPPESEQDAWILVAGLFALHPKASRRGDRSIGTAMQALQDKRGDSATRRFEQLLGRDRAGLPHHLRQIVRLLAAEGIPVNYAALLDDLVVLMGDKYSEDTAHRIRLRWARDFHRKRKTTTTDNGEPAPAPTTVENPA
>NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSATFDLTTESWIPVVYLDEPDGAETLVGLRELFSSAHRIRRIVGETPPMTAALYRLALAILHRAYGPARLPEWEKLWTTETFAPALLAAYLDRPGLSFDLFDLQRPFLQCPGLPEGKKSTVAKLIPHRAVGNRVTLFDHTTAQDRVELTPAAAARWLVTAQAFDPGGMKTPYKTDKSSERAPCNYFGVVLVEGANLKETLLLNAVRYDAQASDDAPAWEAPTPSPEPDKRRSRGWTDVLTWPSRRICLLPEHTNGATVVANAVLTPGTRLVGERPEIERMAAYRTPRTPSGKPKPDAPMLPIRLQPVRGVWRHSVELLLVDPWSEERTRLRPQALKQLATLAEHGSIPADTVYTLRVFGQRLDANASVVEAYLEEEVPAPVALIRAGDDALTGLVGCAIELAEEAGAALRAMQREYHKDMRAEPDVTLDLAYWPALPTPFAAFLRALNDARLAGQSEQRAMAGWRRAVTSVAEQAADSWAAGIAADGRSLNMIGKHLGAVLDRLRTIARTYDAQIAKYLTKDGHE
>NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein
MTGGDDELAELSVRVVLYRRDQDGELKPVYPDSDGLLESATVLAAPINVPAAVVRALLDSEVPADFAADPWLNRHRALVFTDGQCRVAGYELRYHDKFGVYASEET
>NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3
MLDTAAVAERLAPLLLRGRVRSELAAAFGVLGDAWGWTAFLCAVHDLGKYSPTFQALNFPLSSARLGSWAVRDLELVAKLHGVPRRVDTPHGLLTALHLQELLVSWGASRRTAVMIAAALGGHHGHFPAGEVVAQARREINAHGERVWAEQRTTLVAELARLRGLPDPRTLDWAQVDLSVPAAVGLAALTTVSDWIASDTSNFAFAEDEVDLAAYAKDAAVQAEAAVDRLKMSSWSPPGGARFDELFGQSPRSVQEVIERVTADLEGSALVVVEAPTGEGKTKAALQATATMVSQFGLAGSYLGMPTQATSNQMFAVMQAMLTRLGDPTTVSLVHSAAREVLAEPAEVGVDEPGTLDAEAQAWFTRKRSLLSVLGCGTIDQALKGAFRSGHVFVRLAGLANKVVVFDEVHAYDTYMSTLLQRLLMWLGALGAPVVLLSATLPSSRRAELIAAWQAGYRGCYPQEINVPPASKPYPRVTVADTAEVVDHPVEISELNRDRVVHLEHVPDERVVDWLLVAAQGRCVAVVHNLVRRATETYAELERRIKELPEEDRPVLLAINGTLPTGARRRVEQELQGFFGENGMRPRRAIVVGTQAIEQSLDLDFDALITDLAPIDLVFQRAGRVHRHRRDAARGRLTVAITGVVDTPAGPQFPAYLRTVYAPIVLMRTWAALKDLDRIESWTTMAQLVDEVYGDQVACPRGWEAAWRRESDRLAVAQHNDREAAAESYLPQPHMVEVLSELTERPRALRTRKSTGRKR

Crispr_ID: NC_017186_23

• CRISPR_ID: NC_017186_23
• CRISPR_location: 6444434-6444702
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NC_017186_23

Consensus_repeat	Method
GTCGTCCCCTCGCAAGCGGGGCTG	CRISPRCasFinder

spacers of NC_017186_23

>23.1|6444458|37|NC_017186|CRISPRCasFinder
GTCCCGTAGGTCCCAGGACACGACTCCTGGCGCCCCC
>23.2|6444519|37|NC_017186|CRISPRCasFinder
ATCCCGTCTCCGGGTTGAACCCGAGCCGCCAGTCCAC
>23.3|6444580|37|NC_017186|CRISPRCasFinder
ATCCCTGGATCTGGAGTCGGTCGTACTCGCCGAGGTT
>23.4|6444641|37|NC_017186|CRISPRCasFinder
GTCCCCAGGAGTCCGGCGACAACCCGACTGTGGTGAA

CRISPR arrays and Neighbor proteins around NC_017186_23

CRISPR arrays

The CRISPR arrays of NC_017186_23

>merge|NC_017186|23|6444434-6444702|CRISPRCasFinder
GTCGTCCCCTCGCAAGCGGGGCTGGTCCCGTAGGTCCCAGGACACGACTCCTGGCGCCCCCGTCGTCCCCTCGCAAGCGGAGCTGATCCCGTCTCCGGGTTGAACCCGAGCCGCCAGTCCACGTCGTCTCCGCGCACTCGGGGCTGATCCCTGGATCTGGAGTCGGTCGTACTCGCCGAGGTTGTCGTCCCTGCGCACGCGGGGCTGGTCCCCAGGAGTCCGGCGACAACCCGACTGTGGTGAAGTTGTCCTCGCGTAGGCGGGGCTGG

>NC_017186|23|22|6444434-6444702|CRISPRCasFinder
GTCGTCCCCTCGCAAGCGGGGCTG	GTCCCGTAGGTCCCAGGACACGACTCCTGGCGCCCCC
GTCGTCCCCTCGCAAGCGGAGCTG	ATCCCGTCTCCGGGTTGAACCCGAGCCGCCAGTCCAC
GTCGTCTCCGCGCACTCGGGGCTG	ATCCCTGGATCTGGAGTCGGTCGTACTCGCCGAGGTT
GTCGTCCCTGCGCACGCGGGGCTG	GTCCCCAGGAGTCCGGCGACAACCCGACTGTGGTGAA
GTTGTCCTCGCGTAGGCGGGGCTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NC_017186.1|WP_013223344.1|6453920_6454244_-|IS3-family-transposase	unknown	unknown	gnl|CDD|225511
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|378243
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	unknown	unknown	gnl|CDD|375821
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|379021
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
NC_017186.1|WP_013227617.1|6454593_6456450_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|379274

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.9e-55	182.0	0.0
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	1.5e-46	153.2	0.3
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	3e-31	103.3	3.9
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.9e-59	195.7	0.0
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	2.3e-96	318.3	3.8
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	5e-111	366.4	1.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.80328e-21
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.75313e-78
NC_017186.1|WP_013223344.1|6453920_6454244_-|IS3-family-transposase	gnl|CDD|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.26793e-07
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.02918e-12
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.56766e-47
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	7.65375e-42
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	gnl|CDD|375821	pfam18395, Cas3_C, Cas3 C-terminal domain. This is the C-temrinal domain of Cas3 proteins. The C-terminal domain (CTD) is shown to completely wrap ssDNA inside the helicase. Deletion of the CTD (aa 819-924) reduced CRISPR interference. It is suggested that the CTD regulates the N-terminal HD nuclease activity by functioning as a substrate filter.	5.47198e-09
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	0.00914745
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	gnl|CDD|379021	pfam13020, DUF3883, Domain of unknown function (DUF3883). This is a domain is uncharacterized. It is found on restriction endonucleases.	1.15745e-05
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.44632e-24
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	gnl|CDD|379274	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies).	1.9456e-07
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.53205e-80
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	9.17843e-107
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	9.95055e-141

Protein sequences

>NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein
MLRLFDAPVYRDWLFWFMLAWAALDFVSVLTLGPPSGLPRWLTALIGAAFFALVCGLVPAWIRLRLRRRRHGHGRMATKER
>NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease
MRKTVRVLPDMDRWRQLISEYGQLQQLTGHTPQTRGQRFNNMIAELLQCWGIQATANVRAAGEIDVAFAIDGVRFVVEAKWEKTKADTGRIAKLQKRVRQRLSGTYGVFLSMSGYSPEALDDIADGDRLEVLLLSIEHWEAMLGGLVPPQELFNLVRDRASFYGEPYTPLAQLFAPAEIPDIRLGPPSEMTDGPLLEAVDGLDAQVVLSGIESGQLGIACHGQNSLLVTTEHGILDVDFEAHTVTMAAPVPDCQRNVLANEDGSIVFLRRSGVGLFRDGQITTVGGGLSGNSCLCRHPDGSLWVFDNGGLLDHSASVTRLDDKLGLQKRHKINYSPANAFTSA
>NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase
MDRGTEAWLRSLTFDRVGVRLAFEEAFDAVLATRAQRARLDAAITELAAPPVFAPVMGRLACLHGVSTLTAFGLVTEIGDWRRFTGASIGAYVSLVPADSSSGEHRHQGAITKTGNSDGQRLLVEAA
>NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein
MIEEPVELAKDLTRLVLQQADSVVAMYLAGAKYEQPVTREQKESIESIIAADYDGRTVVELLQNGHDAHDSGRSDGKLEFLLDENEGAHGVLYAANGGRPLDQENFRSMCLIARSSKRPDEGIGNKGVGFKSVLQLSDCPEVYSARHEGAGRFDGFRFRFGRPDDFDGLAARSKENWPGLADELRENVSTLKITVPLFETPTVVEDFARRGYSTVVRLPLRSASTRDHARDQLEELAHDEVPFHLFLTRVAEIVVRSQAGETESRRRLTRSTRARRGTSTLSVEHIDLGEQREYVILKRVVAETGIRAAIRASLDDNAIGSGWAGWQGAAEVSVAVPLGAALSQGRVYTFLPLGPGSPCPIAALVNGPFFTRLDRRDVHESIPLNDFLFAEIAALCADAVVAACRGDLELPDEVPLDLVCWAPGWTQRLIAALQALGVELVDLPVLPPLQHQGEGLTFKSALLWSYRGAVFTPEAVTAAGETRLIRYSIDEQRLRRLRKLAKATDHPVEARPADLAGFAETLADDLLRRGESYEVWAGFYDDLSVVLTDVTLIRGHRVFLTEGGILRTSIEDDDLMIYFGPVRGEAGELPELPEVVRDRLAFMPADINWSDERGQRPGRRWLEAIVREYRTDAVLDLIGKVMYDTEAEEVRSACLRFAFDLWQDTPAERRATALGRAGLLVRTRSGWKAPAEAYFDAGWGGPAGKIDRQLADLVKATALISGTLAAVGQSLLFKPELGEATLDDVRTFFEALGVRHGLVPLTVRASRFQLQGKTLKNPRTVPVFPIEISVATQAAWRELAARHSGKPSYDSTRYQPAGGIAYLPGQEEWSEFDDTARRLYFQLVLHGLEVWPATTLWTYFQASSDSVRVTWPTFVAAFLVRADWIPQTTPGDRGKQFFRPMSDAWWVGNTDTPDYLSADPAAFRSLLTDRVRVHLQRLGARFWDDPGTAADRLRELTSVVRLRGPRMSLVRNAYEQAWRDLADRGEEVPHEVIVSVHGSLGVLDLDQEGPAVYTLDEDGAVQAALLIQTPLPMLAVRSPGVAERVRQTLVSDGVSRLRAASAATVQVLADGTDPLTMKSQPLTDLGGDWLPLLVDAIADRRRQALPAAGITVGATAGALRDSVGLVLADSITAVIDGHPVDQEFAPSSMRVVSPEGDPVIVALRGTGEPWVVLQSAAAALAEFRGGPPIADSVRLALIDLTQRCGDRTPTLDDLAVVLKLPVTELQSLAGDAASTRFEVTPVLGLLACLDPGIAEELQGDRIGDQQEMLDWLSRRGFDADEILALAGQNDLLDATRQLDIPLAQANAGLRAVNLPLLHNDIGHRQQFDAYLQRHRPELQDQLRDRFVARFRRGEPLDEYLRLRDLPGLEPDSTWLDTYWHLPDHVVQARLDLWLASVGEPLAGKDRLPPVDELRDRGRRAVMRTLERARIVIEAWLQRNTAGTGARPAEIAGTLEKMVQTGFLDFEVPRTSAVVVWLGEHGQWPVGMPATTEPRQLDLTDGDLKAAESRLNAGHDTAKRRTETVRYAGKTYSTGTEDRDSLIRAVRESVPQGVLDTSATADRMAPLPPSSSAVSGSSSGEWRAPVLSAEKTRLIGLAGEIVAGEWLNAKFGLQPEDTWVSGYRAEYLADGKGNDSCGYDFLVTLPDRTLLYEVKATTDNARQFTLGESEVRRANALRPHEEYHILFISNVLDPDKMRLRVLPNPFSVGGLASYQVVGRSLNLRFRSAD
>NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein
MMTKHPSNSDLPHEGDLNHGEERDRLTRPAVRPIPKWVVVTGVPLMMVIAISAAWLLLSTGATRDQLDALRTAGTLGVGFGGVVALWLAVRRQRSTEHDLLQKYQAHELAERVAAQNQAAADRAAAHAEHDARERRLTDLYLKAVEHLGSAHAPVRHGGLYALERVAQDNPSQRQTVVDVVCAYLRAPYTPPNTSRASRLGLKRPLQSSTRSRATNSARARETTTTSAHTRTISASLEEREVRMTAQRLLKRHLSLDIHDNSTGLFWDNIDLDLAGATLVSFDFRGCRVKHCTFLHSTFVGPARFDNAVFTGEASFARSAFTAEARFSGATFANETWFKGATFTDGPIFNGTTFSGEYFFQEVNFAGNAQFDGTLFTEGTPVEVSAHLDGQSRSASP
>NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein
MAFPNRWTASSSAAAALANSPTRRIREVQRIEQGMGRGVRDSDDHCAVLLVGSKLAMATRDPDWKKLFSPATRAQLDLSNQVAVQLKGQGLDAVRSALTACLDRDPNWVERSRRALAEIRYLDAGTIRPEAIAIRAAFDLASAGQYSAAADEIQRAINGIEDTLLRTEGQLPAPRHPPSSPSSSKASPSRRTERCSSRWSE
>NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase
MDDVEKWCPEPLWLLAQPLLPEAPQRHQGGGRRRLDDRVVLAAILYVLQTGCAWSALPASFGVSAPTAHRRFTEWVETEVFARLHQAVLDLLGSAGAIDWSRASVDGMHVRAVKGGDLTGPSPVDRGKRGSKIHAISDRSGLPLAVGVSAANRNDHLELEAVVDAVVPVKGPAGRPRRRPRKLHADKGYDYPTCRKALRRRGIIARIARRGIESPKRLGRHRYVIERTLEWVSRFRRLARRYERKAAHFTAFTQLACAVICYRRAIKLDLLTHNNPK
>NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein
MLGINATLADIEWDEDRTPQAEAAWERLGSHLGFTSTRPEKLYGKGPDNLWALAGDRHAVVEMKTGCTTDMIAKKDVDQLGGSVRWDQDNHPGITSIPGITSIPIMVHPSRIVNHQGTPVPGMRVITAAKLDELKTAVRSFAVALADGQGRWYDEQGVSVQLTQARLTAGKFLNAFTEVNLVES
>NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein
MSPRERDAHELRQLARETADQLASFAHIFSAADRRNDRVTPPELFTLAGLLEDAAAVLGEDARVKPLIFSFKDTIVPQKELNFDIAYRYLTPIVRAIRSRYNLPGSPHASPASKPRRRVDVRIDTDRHDRAQSDGDRDSGT
>NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein
MSLTDEQWDALGLDRVVVRDRAEFFIGYAGSEAPLFDVDGVIDAFRDGPLGDETDQKVAKFTDTDDAGPAGLLRRRMAEAAGRPGRRPWARTAERADALRHAAQAALLGDTREGRNLLLQSASLYRELGLPFGDFLSAAAVGPGDAAFEAAGQLRSIIFGSETAPEARRVDEGYFSLPRRLLAPAQQIAVLFTALSSADGVDGFGIGIDLLRRASQATQATSVGVTGRPVALWWECGVRLAELTYGRPSARDDLRTTIAELATAHGQALRTAQFDRYHWPRALSKMDLVDLDLTGLTAISNRVLRQLGEPEWSMFEDFRDLTPLSQVSVQVGIRLSGPGRPRTPASGPSPSPEPTPGPAAASDYVPESRSPSLWARS
>NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MFLSKLTINVHSRTFRRDYANVHDMHRTLMSVYPDVPADTPKRQAHGVLWRLDSNRGSYVQYVQSHTRPDWDKLPDGHLNAPAEIRPLQPVLDAITAGRKLAFRFVANPTRCDNKTRQRIPLRQPADQIDWLIRQGQTHGFVIPATAAGPDIAITPTATITGRKSEPSKITIEPVRFDGHLIVTDPAAFTDAFSNGIGRAKAYGCGLISLAPSRTL
>NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTHTLALCFDAPMQSWGLRSRGILRDTAREPTKSGVVGLLAAATGVERDDEAGIATLAALRLGVRVDREGLLERDYHTTQNVPTTTGSGHRTVVSERYYLADALFLVAIEGPETLLSELADAVTNPRWPLFFGRRAFVSARPLFDDGLHAGNLEQILREHRWLEHPDRAGAMIPGQQQIALRTVVDCPTGTVGAEPRHDVPRSFAHGARSFATRTVLVGEVPLTDNMIPAGDTTCS
>NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MIIELHLLQSFPVSNLNRDDVGQPKTATFGGSTRGRISSQCLKRSARQLFTDHGLTDTETGIRTKRLRNEAAALLTKRGRDEQEAAGVVTAGLEQLGFGVDQDKGLTEYLLFVGTTAIEHLAGYCDDRWDTLAAVAAAKDGKKKPAKAKPDKNDLAEAKRMLDATRVADVALFGRMIADNKDFNVDAASQVAHALSTHAVATEFDYYTAVDDLKPEAESGADMIGTVDFNAACYYRYANLDLDRLRQNLAGDDELVARAARAWLGAFIHAVPSGKQNSMAARTMPDTLLGVVRDGGAWNLANAFLKPVTGEDIMAASTASLTQHFQQLRAFYGSSSIRAAVAASVTGQLPDMDGTDTAASIDEFTSRILAAGTTPA
>NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSTPVAQRRDGFISALYALNAGLESSIPKRRSEARQVLARLRRSLVTARPEPAAYEVVFRHDPPESEQDAWILVAGLFALHPKASRRGDRSIGTAMQALQDKRGDSATRRFEQLLGRDRAGLPHHLRQIVRLLAAEGIPVNYAALLDDLVVLMGDKYSEDTAHRIRLRWARDFHRKRKTTTTDNGEPAPAPTTVENPA
>NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSATFDLTTESWIPVVYLDEPDGAETLVGLRELFSSAHRIRRIVGETPPMTAALYRLALAILHRAYGPARLPEWEKLWTTETFAPALLAAYLDRPGLSFDLFDLQRPFLQCPGLPEGKKSTVAKLIPHRAVGNRVTLFDHTTAQDRVELTPAAAARWLVTAQAFDPGGMKTPYKTDKSSERAPCNYFGVVLVEGANLKETLLLNAVRYDAQASDDAPAWEAPTPSPEPDKRRSRGWTDVLTWPSRRICLLPEHTNGATVVANAVLTPGTRLVGERPEIERMAAYRTPRTPSGKPKPDAPMLPIRLQPVRGVWRHSVELLLVDPWSEERTRLRPQALKQLATLAEHGSIPADTVYTLRVFGQRLDANASVVEAYLEEEVPAPVALIRAGDDALTGLVGCAIELAEEAGAALRAMQREYHKDMRAEPDVTLDLAYWPALPTPFAAFLRALNDARLAGQSEQRAMAGWRRAVTSVAEQAADSWAAGIAADGRSLNMIGKHLGAVLDRLRTIARTYDAQIAKYLTKDGHE
>NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein
MTGGDDELAELSVRVVLYRRDQDGELKPVYPDSDGLLESATVLAAPINVPAAVVRALLDSEVPADFAADPWLNRHRALVFTDGQCRVAGYELRYHDKFGVYASEET
>NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3
MLDTAAVAERLAPLLLRGRVRSELAAAFGVLGDAWGWTAFLCAVHDLGKYSPTFQALNFPLSSARLGSWAVRDLELVAKLHGVPRRVDTPHGLLTALHLQELLVSWGASRRTAVMIAAALGGHHGHFPAGEVVAQARREINAHGERVWAEQRTTLVAELARLRGLPDPRTLDWAQVDLSVPAAVGLAALTTVSDWIASDTSNFAFAEDEVDLAAYAKDAAVQAEAAVDRLKMSSWSPPGGARFDELFGQSPRSVQEVIERVTADLEGSALVVVEAPTGEGKTKAALQATATMVSQFGLAGSYLGMPTQATSNQMFAVMQAMLTRLGDPTTVSLVHSAAREVLAEPAEVGVDEPGTLDAEAQAWFTRKRSLLSVLGCGTIDQALKGAFRSGHVFVRLAGLANKVVVFDEVHAYDTYMSTLLQRLLMWLGALGAPVVLLSATLPSSRRAELIAAWQAGYRGCYPQEINVPPASKPYPRVTVADTAEVVDHPVEISELNRDRVVHLEHVPDERVVDWLLVAAQGRCVAVVHNLVRRATETYAELERRIKELPEEDRPVLLAINGTLPTGARRRVEQELQGFFGENGMRPRRAIVVGTQAIEQSLDLDFDALITDLAPIDLVFQRAGRVHRHRRDAARGRLTVAITGVVDTPAGPQFPAYLRTVYAPIVLMRTWAALKDLDRIESWTTMAQLVDEVYGDQVACPRGWEAAWRRESDRLAVAQHNDREAAAESYLPQPHMVEVLSELTERPRALRTRKSTGRKR
>NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA
>NC_017186.1|WP_013223344.1|6453920_6454244_-|IS3-family-transposase
MPPRKRRSYPAEYKVEAAHRVIDSGRTIAEVARELGLDAGMLSVWVKDERRRVTAAEVHGENPLEAAERAELLRLRGQVAELEKDNAFLVKASAYFAAMQKNRPGSL
>NC_017186.1|WP_013227617.1|6454593_6456450_-|hypothetical-protein
MSDGDVMVFNGLSRFAVPVEKPVLLDDDGFLLATSDARWRSGEAVSPVPVAELPTEVVSFALLAAGGAGKTVTFTELANAEPDARRIDTSALTIDGLERELDDACFHESAVYLDGLDQAASVEARLFPWLERYLTAPARRGMRSRLACRAAAWDAVLGRALFQQMTAFTVWKLAPLDRDTASKAVEHAIGVSEVDSAAFMKALVGAKLGRLSGCVGQLVAVARYWNAQGVLPRSAADAMKFEIEYLLRETDERRQPRLPLDRSMRVAQRLGAFTMFAGNQALTVRAVGDRATLPVSDLPSDAEPDQPARTIEPLDYGAVLDTALFDSGPAGSVMFRHQRYLEYLAAAYLVQRGIRAGQIPVLLGVHVNGLLPTPRIGVASWLAALAPDLVAQLFIDNAAMFASAAAVVELPSDEARAALVKGLLEAAARDDAEPDWRLDRTGLLHAGLTEQLAEYLGRGPANAPQLWWIARLAAAGGCRTLAPALARAALEPAWFGYVRRAAVAAVADLGEDDLQLSLRQLLAEPTDTDPDADNEVRAAVIDALYPRLLSTVELTQALRPHRSMLFGGYLQSLRELPSRVPENDLADFVAWLADHAWRSDVRDDDQFEDLYAGVIKRA

Crispr_ID: NC_017186_22

• CRISPR_ID: NC_017186_22
• CRISPR_location: 6441951-6442222
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NC_017186_22

Consensus_repeat	Method
GTTGTCCCCGCACGCGCGGGGCTGGTCCC	CRISPRCasFinder

spacers of NC_017186_22

>22.1|6441980|32|NC_017186|CRISPRCasFinder
TGCACGACCGGCCAATCGACCGCCTTGTAGTC
>22.2|6442041|32|NC_017186|CRISPRCasFinder
ACGAAGTAGATGCCCGCGTGCTGGATGGTGAG
>22.3|6442102|31|NC_017186|CRISPRCasFinder
ATGCCGGTCACACCGCTCGGATGCCGCCGTT
>22.4|6442162|32|NC_017186|CRISPRCasFinder
TGGGTGGCCGACTTCCTCGGCCTGGACAAGCT

CRISPR arrays and Neighbor proteins around NC_017186_22

CRISPR arrays

The CRISPR arrays of NC_017186_22

>merge|NC_017186|22|6441951-6442222|CRISPRCasFinder
GTTGTCCCCGCACGCGCGGGGCTGGTCCCTGCACGACCGGCCAATCGACCGCCTTGTAGTCGTTGTCCCCGCACGCGCAGGGCTGGTCCCACGAAGTAGATGCCCGCGTGCTGGATGGTGAGGTTGTCCCCGCACACGCGGGGCTGGTCCCATGCCGGTCACACCGCTCGGATGCCGCCGTTGTCGTCCCCACGCACGCGGAGCTGGTCCTTGGGTGGCCGACTTCCTCGGCCTGGACAAGCTGTCGTCCCCGCGCACGCGGGGCCGGTCCG

>NC_017186|22|21|6441951-6442222|CRISPRCasFinder
GTTGTCCCCGCACGCGCGGGGCTGGTCCC	TGCACGACCGGCCAATCGACCGCCTTGTAGTC
GTTGTCCCCGCACGCGCAGGGCTGGTCCC	ACGAAGTAGATGCCCGCGTGCTGGATGGTGAG
GTTGTCCCCGCACACGCGGGGCTGGTCCC	ATGCCGGTCACACCGCTCGGATGCCGCCGTT
GTCGTCCCCACGCACGCGGAGCTGGTCCT	TGGGTGGCCGACTTCCTCGGCCTGGACAAGCT
GTCGTCCCCGCGCACGCGGGGCCGGTCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|378243
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	unknown	unknown	gnl|CDD|375821
NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|379021
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|379274

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.9e-55	182.0	0.0
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	1.5e-46	153.2	0.3
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	3e-31	103.3	3.9
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.9e-59	195.7	0.0
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	2.3e-96	318.3	3.8
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	5e-111	366.4	1.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.80328e-21
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.75313e-78
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.02918e-12
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.56766e-47
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	7.65375e-42
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	gnl|CDD|375821	pfam18395, Cas3_C, Cas3 C-terminal domain. This is the C-temrinal domain of Cas3 proteins. The C-terminal domain (CTD) is shown to completely wrap ssDNA inside the helicase. Deletion of the CTD (aa 819-924) reduced CRISPR interference. It is suggested that the CTD regulates the N-terminal HD nuclease activity by functioning as a substrate filter.	5.47198e-09
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	0.00914745
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	gnl|CDD|379021	pfam13020, DUF3883, Domain of unknown function (DUF3883). This is a domain is uncharacterized. It is found on restriction endonucleases.	1.15745e-05
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.44632e-24
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	gnl|CDD|379274	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies).	1.9456e-07
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.53205e-80
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	9.17843e-107
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	9.95055e-141

Protein sequences

>NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase
MDRGTEAWLRSLTFDRVGVRLAFEEAFDAVLATRAQRARLDAAITELAAPPVFAPVMGRLACLHGVSTLTAFGLVTEIGDWRRFTGASIGAYVSLVPADSSSGEHRHQGAITKTGNSDGQRLLVEAA
>NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein
MIEEPVELAKDLTRLVLQQADSVVAMYLAGAKYEQPVTREQKESIESIIAADYDGRTVVELLQNGHDAHDSGRSDGKLEFLLDENEGAHGVLYAANGGRPLDQENFRSMCLIARSSKRPDEGIGNKGVGFKSVLQLSDCPEVYSARHEGAGRFDGFRFRFGRPDDFDGLAARSKENWPGLADELRENVSTLKITVPLFETPTVVEDFARRGYSTVVRLPLRSASTRDHARDQLEELAHDEVPFHLFLTRVAEIVVRSQAGETESRRRLTRSTRARRGTSTLSVEHIDLGEQREYVILKRVVAETGIRAAIRASLDDNAIGSGWAGWQGAAEVSVAVPLGAALSQGRVYTFLPLGPGSPCPIAALVNGPFFTRLDRRDVHESIPLNDFLFAEIAALCADAVVAACRGDLELPDEVPLDLVCWAPGWTQRLIAALQALGVELVDLPVLPPLQHQGEGLTFKSALLWSYRGAVFTPEAVTAAGETRLIRYSIDEQRLRRLRKLAKATDHPVEARPADLAGFAETLADDLLRRGESYEVWAGFYDDLSVVLTDVTLIRGHRVFLTEGGILRTSIEDDDLMIYFGPVRGEAGELPELPEVVRDRLAFMPADINWSDERGQRPGRRWLEAIVREYRTDAVLDLIGKVMYDTEAEEVRSACLRFAFDLWQDTPAERRATALGRAGLLVRTRSGWKAPAEAYFDAGWGGPAGKIDRQLADLVKATALISGTLAAVGQSLLFKPELGEATLDDVRTFFEALGVRHGLVPLTVRASRFQLQGKTLKNPRTVPVFPIEISVATQAAWRELAARHSGKPSYDSTRYQPAGGIAYLPGQEEWSEFDDTARRLYFQLVLHGLEVWPATTLWTYFQASSDSVRVTWPTFVAAFLVRADWIPQTTPGDRGKQFFRPMSDAWWVGNTDTPDYLSADPAAFRSLLTDRVRVHLQRLGARFWDDPGTAADRLRELTSVVRLRGPRMSLVRNAYEQAWRDLADRGEEVPHEVIVSVHGSLGVLDLDQEGPAVYTLDEDGAVQAALLIQTPLPMLAVRSPGVAERVRQTLVSDGVSRLRAASAATVQVLADGTDPLTMKSQPLTDLGGDWLPLLVDAIADRRRQALPAAGITVGATAGALRDSVGLVLADSITAVIDGHPVDQEFAPSSMRVVSPEGDPVIVALRGTGEPWVVLQSAAAALAEFRGGPPIADSVRLALIDLTQRCGDRTPTLDDLAVVLKLPVTELQSLAGDAASTRFEVTPVLGLLACLDPGIAEELQGDRIGDQQEMLDWLSRRGFDADEILALAGQNDLLDATRQLDIPLAQANAGLRAVNLPLLHNDIGHRQQFDAYLQRHRPELQDQLRDRFVARFRRGEPLDEYLRLRDLPGLEPDSTWLDTYWHLPDHVVQARLDLWLASVGEPLAGKDRLPPVDELRDRGRRAVMRTLERARIVIEAWLQRNTAGTGARPAEIAGTLEKMVQTGFLDFEVPRTSAVVVWLGEHGQWPVGMPATTEPRQLDLTDGDLKAAESRLNAGHDTAKRRTETVRYAGKTYSTGTEDRDSLIRAVRESVPQGVLDTSATADRMAPLPPSSSAVSGSSSGEWRAPVLSAEKTRLIGLAGEIVAGEWLNAKFGLQPEDTWVSGYRAEYLADGKGNDSCGYDFLVTLPDRTLLYEVKATTDNARQFTLGESEVRRANALRPHEEYHILFISNVLDPDKMRLRVLPNPFSVGGLASYQVVGRSLNLRFRSAD
>NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein
MMTKHPSNSDLPHEGDLNHGEERDRLTRPAVRPIPKWVVVTGVPLMMVIAISAAWLLLSTGATRDQLDALRTAGTLGVGFGGVVALWLAVRRQRSTEHDLLQKYQAHELAERVAAQNQAAADRAAAHAEHDARERRLTDLYLKAVEHLGSAHAPVRHGGLYALERVAQDNPSQRQTVVDVVCAYLRAPYTPPNTSRASRLGLKRPLQSSTRSRATNSARARETTTTSAHTRTISASLEEREVRMTAQRLLKRHLSLDIHDNSTGLFWDNIDLDLAGATLVSFDFRGCRVKHCTFLHSTFVGPARFDNAVFTGEASFARSAFTAEARFSGATFANETWFKGATFTDGPIFNGTTFSGEYFFQEVNFAGNAQFDGTLFTEGTPVEVSAHLDGQSRSASP
>NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein
MAFPNRWTASSSAAAALANSPTRRIREVQRIEQGMGRGVRDSDDHCAVLLVGSKLAMATRDPDWKKLFSPATRAQLDLSNQVAVQLKGQGLDAVRSALTACLDRDPNWVERSRRALAEIRYLDAGTIRPEAIAIRAAFDLASAGQYSAAADEIQRAINGIEDTLLRTEGQLPAPRHPPSSPSSSKASPSRRTERCSSRWSE
>NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase
MDDVEKWCPEPLWLLAQPLLPEAPQRHQGGGRRRLDDRVVLAAILYVLQTGCAWSALPASFGVSAPTAHRRFTEWVETEVFARLHQAVLDLLGSAGAIDWSRASVDGMHVRAVKGGDLTGPSPVDRGKRGSKIHAISDRSGLPLAVGVSAANRNDHLELEAVVDAVVPVKGPAGRPRRRPRKLHADKGYDYPTCRKALRRRGIIARIARRGIESPKRLGRHRYVIERTLEWVSRFRRLARRYERKAAHFTAFTQLACAVICYRRAIKLDLLTHNNPK
>NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein
MLGINATLADIEWDEDRTPQAEAAWERLGSHLGFTSTRPEKLYGKGPDNLWALAGDRHAVVEMKTGCTTDMIAKKDVDQLGGSVRWDQDNHPGITSIPGITSIPIMVHPSRIVNHQGTPVPGMRVITAAKLDELKTAVRSFAVALADGQGRWYDEQGVSVQLTQARLTAGKFLNAFTEVNLVES
>NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein
MSPRERDAHELRQLARETADQLASFAHIFSAADRRNDRVTPPELFTLAGLLEDAAAVLGEDARVKPLIFSFKDTIVPQKELNFDIAYRYLTPIVRAIRSRYNLPGSPHASPASKPRRRVDVRIDTDRHDRAQSDGDRDSGT
>NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein
MSLTDEQWDALGLDRVVVRDRAEFFIGYAGSEAPLFDVDGVIDAFRDGPLGDETDQKVAKFTDTDDAGPAGLLRRRMAEAAGRPGRRPWARTAERADALRHAAQAALLGDTREGRNLLLQSASLYRELGLPFGDFLSAAAVGPGDAAFEAAGQLRSIIFGSETAPEARRVDEGYFSLPRRLLAPAQQIAVLFTALSSADGVDGFGIGIDLLRRASQATQATSVGVTGRPVALWWECGVRLAELTYGRPSARDDLRTTIAELATAHGQALRTAQFDRYHWPRALSKMDLVDLDLTGLTAISNRVLRQLGEPEWSMFEDFRDLTPLSQVSVQVGIRLSGPGRPRTPASGPSPSPEPTPGPAAASDYVPESRSPSLWARS
>NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein
MIVQWCCKGMAKLPEREAERILTGGTGIRCRSWLTVAPKPFPLGKNLDRLTEDNLDRHVNKYSDPDPVTGAPFHDVTPFISLSAGCVDRQVAIERNETHSALRTALTFATTDYSQPGPNWPRCAGWVFYCYVLTGVNRAVSIPSVAEEYRELNLGRSYSRWQPQGEVMAKINVPSRQILCAVHWTPLPSGESKWDEVLWNLRFTHPAALLGERNML
>NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein
MEIAKLIVAALTPLSVALIGVVLTRSMRRLEHSNWLNQKLIEKRIEVLGEALPKLNDLYCYFSWIGTWASLSPVDVLQRKRDLDRLFHANRAFFTSSAFDVYGAFIDLLFETYAQPGKGARLRTEMTSHNGNRADVYPKKWEEGWSEMFSGVPRTSSLLTVKKCYEGLVMTFSAEVGIERSDAVGR
>NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease
MRKTVRVLPDMDRWRQLISEYGQLQQLTGHTPQTRGQRFNNMIAELLQCWGIQATANVRAAGEIDVAFAIDGVRFVVEAKWEKTKADTGRIAKLQKRVRQRLSGTYGVFLSMSGYSPEALDDIADGDRLEVLLLSIEHWEAMLGGLVPPQELFNLVRDRASFYGEPYTPLAQLFAPAEIPDIRLGPPSEMTDGPLLEAVDGLDAQVVLSGIESGQLGIACHGQNSLLVTTEHGILDVDFEAHTVTMAAPVPDCQRNVLANEDGSIVFLRRSGVGLFRDGQITTVGGGLSGNSCLCRHPDGSLWVFDNGGLLDHSASVTRLDDKLGLQKRHKINYSPANAFTSA
>NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein
MLRLFDAPVYRDWLFWFMLAWAALDFVSVLTLGPPSGLPRWLTALIGAAFFALVCGLVPAWIRLRLRRRRHGHGRMATKER
>NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MFLSKLTINVHSRTFRRDYANVHDMHRTLMSVYPDVPADTPKRQAHGVLWRLDSNRGSYVQYVQSHTRPDWDKLPDGHLNAPAEIRPLQPVLDAITAGRKLAFRFVANPTRCDNKTRQRIPLRQPADQIDWLIRQGQTHGFVIPATAAGPDIAITPTATITGRKSEPSKITIEPVRFDGHLIVTDPAAFTDAFSNGIGRAKAYGCGLISLAPSRTL
>NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTHTLALCFDAPMQSWGLRSRGILRDTAREPTKSGVVGLLAAATGVERDDEAGIATLAALRLGVRVDREGLLERDYHTTQNVPTTTGSGHRTVVSERYYLADALFLVAIEGPETLLSELADAVTNPRWPLFFGRRAFVSARPLFDDGLHAGNLEQILREHRWLEHPDRAGAMIPGQQQIALRTVVDCPTGTVGAEPRHDVPRSFAHGARSFATRTVLVGEVPLTDNMIPAGDTTCS
>NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MIIELHLLQSFPVSNLNRDDVGQPKTATFGGSTRGRISSQCLKRSARQLFTDHGLTDTETGIRTKRLRNEAAALLTKRGRDEQEAAGVVTAGLEQLGFGVDQDKGLTEYLLFVGTTAIEHLAGYCDDRWDTLAAVAAAKDGKKKPAKAKPDKNDLAEAKRMLDATRVADVALFGRMIADNKDFNVDAASQVAHALSTHAVATEFDYYTAVDDLKPEAESGADMIGTVDFNAACYYRYANLDLDRLRQNLAGDDELVARAARAWLGAFIHAVPSGKQNSMAARTMPDTLLGVVRDGGAWNLANAFLKPVTGEDIMAASTASLTQHFQQLRAFYGSSSIRAAVAASVTGQLPDMDGTDTAASIDEFTSRILAAGTTPA
>NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSTPVAQRRDGFISALYALNAGLESSIPKRRSEARQVLARLRRSLVTARPEPAAYEVVFRHDPPESEQDAWILVAGLFALHPKASRRGDRSIGTAMQALQDKRGDSATRRFEQLLGRDRAGLPHHLRQIVRLLAAEGIPVNYAALLDDLVVLMGDKYSEDTAHRIRLRWARDFHRKRKTTTTDNGEPAPAPTTVENPA
>NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSATFDLTTESWIPVVYLDEPDGAETLVGLRELFSSAHRIRRIVGETPPMTAALYRLALAILHRAYGPARLPEWEKLWTTETFAPALLAAYLDRPGLSFDLFDLQRPFLQCPGLPEGKKSTVAKLIPHRAVGNRVTLFDHTTAQDRVELTPAAAARWLVTAQAFDPGGMKTPYKTDKSSERAPCNYFGVVLVEGANLKETLLLNAVRYDAQASDDAPAWEAPTPSPEPDKRRSRGWTDVLTWPSRRICLLPEHTNGATVVANAVLTPGTRLVGERPEIERMAAYRTPRTPSGKPKPDAPMLPIRLQPVRGVWRHSVELLLVDPWSEERTRLRPQALKQLATLAEHGSIPADTVYTLRVFGQRLDANASVVEAYLEEEVPAPVALIRAGDDALTGLVGCAIELAEEAGAALRAMQREYHKDMRAEPDVTLDLAYWPALPTPFAAFLRALNDARLAGQSEQRAMAGWRRAVTSVAEQAADSWAAGIAADGRSLNMIGKHLGAVLDRLRTIARTYDAQIAKYLTKDGHE
>NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein
MTGGDDELAELSVRVVLYRRDQDGELKPVYPDSDGLLESATVLAAPINVPAAVVRALLDSEVPADFAADPWLNRHRALVFTDGQCRVAGYELRYHDKFGVYASEET
>NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3
MLDTAAVAERLAPLLLRGRVRSELAAAFGVLGDAWGWTAFLCAVHDLGKYSPTFQALNFPLSSARLGSWAVRDLELVAKLHGVPRRVDTPHGLLTALHLQELLVSWGASRRTAVMIAAALGGHHGHFPAGEVVAQARREINAHGERVWAEQRTTLVAELARLRGLPDPRTLDWAQVDLSVPAAVGLAALTTVSDWIASDTSNFAFAEDEVDLAAYAKDAAVQAEAAVDRLKMSSWSPPGGARFDELFGQSPRSVQEVIERVTADLEGSALVVVEAPTGEGKTKAALQATATMVSQFGLAGSYLGMPTQATSNQMFAVMQAMLTRLGDPTTVSLVHSAAREVLAEPAEVGVDEPGTLDAEAQAWFTRKRSLLSVLGCGTIDQALKGAFRSGHVFVRLAGLANKVVVFDEVHAYDTYMSTLLQRLLMWLGALGAPVVLLSATLPSSRRAELIAAWQAGYRGCYPQEINVPPASKPYPRVTVADTAEVVDHPVEISELNRDRVVHLEHVPDERVVDWLLVAAQGRCVAVVHNLVRRATETYAELERRIKELPEEDRPVLLAINGTLPTGARRRVEQELQGFFGENGMRPRRAIVVGTQAIEQSLDLDFDALITDLAPIDLVFQRAGRVHRHRRDAARGRLTVAITGVVDTPAGPQFPAYLRTVYAPIVLMRTWAALKDLDRIESWTTMAQLVDEVYGDQVACPRGWEAAWRRESDRLAVAQHNDREAAAESYLPQPHMVEVLSELTERPRALRTRKSTGRKR
>NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA

Crispr_ID: NC_017186_20

• CRISPR_ID: NC_017186_20
• CRISPR_location: 6438603-6438875
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 4 spacers
• Cas_protein_info: cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NC_017186_20

Consensus_repeat	Method
GTTGTCCCCGCACGCGCGGGGCTGGTCC	PILER-CR
GTTGTCCCCGCACGCGCGGGGCTGGTCCC	CRISPRCasFinder
GTTGTCCCCGCACGCGCGGGGCTGGTCC	CRT

spacers of NC_017186_20

>20.1|6438631|33|NC_017186|PILER-CR,CRT
GGGAGCACTCGCATGACGACCACGGAGCCGGCG
>20.2|6438692|33|NC_017186|PILER-CR,CRT
CTGGTTGATCCGGATGTCCCAGTCGTCCACCGC
>20.3|6438753|33|NC_017186|PILER-CR,CRT
CACGGTGGCGGTGGCCTGCTGATACTGGGCGTC
>20.4|6438632|32|NC_017186|CRISPRCasFinder
GGAGCACTCGCATGACGACCACGGAGCCGGCG
>20.5|6438693|32|NC_017186|CRISPRCasFinder
TGGTTGATCCGGATGTCCCAGTCGTCCACCGC
>20.6|6438754|32|NC_017186|CRISPRCasFinder
ACGGTGGCGGTGGCCTGCTGATACTGGGCGTC
>20.7|6438815|32|NC_017186|CRISPRCasFinder
GACGGTTGGGGCAACCTGAAGGCGGCCGGCCT
>20.8|6438814|33|NC_017186|CRT
AGACGGTTGGGGCAACCTGAAGGCGGCCGGCCT

CRISPR arrays and Neighbor proteins around NC_017186_20

CRISPR arrays

The CRISPR arrays of NC_017186_20

>merge|NC_017186|20|6438603-6438875|PILER-CR,CRISPRCasFinder,CRT
GTTGTCCCTGCACGCGCGGGGCTGGTCCGGGAGCACTCGCATGACGACCACGGAGCCGGCGGTTGTCCCCGCACGCGCGGGGCTGGTCCCTGGTTGATCCGGATGTCCCAGTCGTCCACCGCGTTGTCCCCGCACGCGCGGGGCTGGTCCCACGGTGGCGGTGGCCTGCTGATACTGGGCGTCGTTGTCCCCGCACGCGCGGGGCTGGTCCAGACGGTTGGGGCAACCTGAAGGCGGCCGGCCTGTCGTCCCCGCACGCGCGGGGGCTAGTAC

>NC_017186|20|3|6438603-6438813|PILER-CR
GTTGTCCCTGCACGCGCGGGGCTGGTCC	GGGAGCACTCGCATGACGACCACGGAGCCGGCG
GTTGTCCCCGCACGCGCGGGGCTGGTCC	CTGGTTGATCCGGATGTCCCAGTCGTCCACCGC
GTTGTCCCCGCACGCGCGGGGCTGGTCC	CACGGTGGCGGTGGCCTGCTGATACTGGGCGTC
GTTGTCCCCGCACGCGCGGGGCTGGTCC

>NC_017186|20|19|6438603-6438875|CRISPRCasFinder
GTTGTCCCTGCACGCGCGGGGCTGGTCCG	GGAGCACTCGCATGACGACCACGGAGCCGGCG
GTTGTCCCCGCACGCGCGGGGCTGGTCCC	TGGTTGATCCGGATGTCCCAGTCGTCCACCGC
GTTGTCCCCGCACGCGCGGGGCTGGTCCC	ACGGTGGCGGTGGCCTGCTGATACTGGGCGTC
GTTGTCCCCGCACGCGCGGGGCTGGTCCA	GACGGTTGGGGCAACCTGAAGGCGGCCGGCCT
GTCGTCCCCGCACGCGCGGGGGCTAGTAC

>NC_017186|20|4|6438603-6438874|CRT
GTTGTCCCTGCACGCGCGGGGCTGGTCC	GGGAGCACTCGCATGACGACCACGGAGCCGGCG
GTTGTCCCCGCACGCGCGGGGCTGGTCC	CTGGTTGATCCGGATGTCCCAGTCGTCCACCGC
GTTGTCCCCGCACGCGCGGGGCTGGTCC	CACGGTGGCGGTGGCCTGCTGATACTGGGCGTC
GTTGTCCCCGCACGCGCGGGGCTGGTCC	AGACGGTTGGGGCAACCTGAAGGCGGCCGGCCT
GTCGTCCCCGCACGCGCGGGGGCTAGTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|378243
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	unknown	unknown	gnl|CDD|375821
NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|379021
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|379274

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.9e-55	182.0	0.0
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	1.5e-46	153.2	0.3
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	3e-31	103.3	3.9
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.9e-59	195.7	0.0
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	2.3e-96	318.3	3.8
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	5e-111	366.4	1.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.80328e-21
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.75313e-78
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.02918e-12
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.56766e-47
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	7.65375e-42
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	gnl|CDD|375821	pfam18395, Cas3_C, Cas3 C-terminal domain. This is the C-temrinal domain of Cas3 proteins. The C-terminal domain (CTD) is shown to completely wrap ssDNA inside the helicase. Deletion of the CTD (aa 819-924) reduced CRISPR interference. It is suggested that the CTD regulates the N-terminal HD nuclease activity by functioning as a substrate filter.	5.47198e-09
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	0.00914745
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	gnl|CDD|379021	pfam13020, DUF3883, Domain of unknown function (DUF3883). This is a domain is uncharacterized. It is found on restriction endonucleases.	1.15745e-05
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.44632e-24
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	gnl|CDD|379274	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies).	1.9456e-07
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.53205e-80
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	9.17843e-107
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	9.95055e-141

Protein sequences

>NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase
MDRGTEAWLRSLTFDRVGVRLAFEEAFDAVLATRAQRARLDAAITELAAPPVFAPVMGRLACLHGVSTLTAFGLVTEIGDWRRFTGASIGAYVSLVPADSSSGEHRHQGAITKTGNSDGQRLLVEAA
>NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein
MIEEPVELAKDLTRLVLQQADSVVAMYLAGAKYEQPVTREQKESIESIIAADYDGRTVVELLQNGHDAHDSGRSDGKLEFLLDENEGAHGVLYAANGGRPLDQENFRSMCLIARSSKRPDEGIGNKGVGFKSVLQLSDCPEVYSARHEGAGRFDGFRFRFGRPDDFDGLAARSKENWPGLADELRENVSTLKITVPLFETPTVVEDFARRGYSTVVRLPLRSASTRDHARDQLEELAHDEVPFHLFLTRVAEIVVRSQAGETESRRRLTRSTRARRGTSTLSVEHIDLGEQREYVILKRVVAETGIRAAIRASLDDNAIGSGWAGWQGAAEVSVAVPLGAALSQGRVYTFLPLGPGSPCPIAALVNGPFFTRLDRRDVHESIPLNDFLFAEIAALCADAVVAACRGDLELPDEVPLDLVCWAPGWTQRLIAALQALGVELVDLPVLPPLQHQGEGLTFKSALLWSYRGAVFTPEAVTAAGETRLIRYSIDEQRLRRLRKLAKATDHPVEARPADLAGFAETLADDLLRRGESYEVWAGFYDDLSVVLTDVTLIRGHRVFLTEGGILRTSIEDDDLMIYFGPVRGEAGELPELPEVVRDRLAFMPADINWSDERGQRPGRRWLEAIVREYRTDAVLDLIGKVMYDTEAEEVRSACLRFAFDLWQDTPAERRATALGRAGLLVRTRSGWKAPAEAYFDAGWGGPAGKIDRQLADLVKATALISGTLAAVGQSLLFKPELGEATLDDVRTFFEALGVRHGLVPLTVRASRFQLQGKTLKNPRTVPVFPIEISVATQAAWRELAARHSGKPSYDSTRYQPAGGIAYLPGQEEWSEFDDTARRLYFQLVLHGLEVWPATTLWTYFQASSDSVRVTWPTFVAAFLVRADWIPQTTPGDRGKQFFRPMSDAWWVGNTDTPDYLSADPAAFRSLLTDRVRVHLQRLGARFWDDPGTAADRLRELTSVVRLRGPRMSLVRNAYEQAWRDLADRGEEVPHEVIVSVHGSLGVLDLDQEGPAVYTLDEDGAVQAALLIQTPLPMLAVRSPGVAERVRQTLVSDGVSRLRAASAATVQVLADGTDPLTMKSQPLTDLGGDWLPLLVDAIADRRRQALPAAGITVGATAGALRDSVGLVLADSITAVIDGHPVDQEFAPSSMRVVSPEGDPVIVALRGTGEPWVVLQSAAAALAEFRGGPPIADSVRLALIDLTQRCGDRTPTLDDLAVVLKLPVTELQSLAGDAASTRFEVTPVLGLLACLDPGIAEELQGDRIGDQQEMLDWLSRRGFDADEILALAGQNDLLDATRQLDIPLAQANAGLRAVNLPLLHNDIGHRQQFDAYLQRHRPELQDQLRDRFVARFRRGEPLDEYLRLRDLPGLEPDSTWLDTYWHLPDHVVQARLDLWLASVGEPLAGKDRLPPVDELRDRGRRAVMRTLERARIVIEAWLQRNTAGTGARPAEIAGTLEKMVQTGFLDFEVPRTSAVVVWLGEHGQWPVGMPATTEPRQLDLTDGDLKAAESRLNAGHDTAKRRTETVRYAGKTYSTGTEDRDSLIRAVRESVPQGVLDTSATADRMAPLPPSSSAVSGSSSGEWRAPVLSAEKTRLIGLAGEIVAGEWLNAKFGLQPEDTWVSGYRAEYLADGKGNDSCGYDFLVTLPDRTLLYEVKATTDNARQFTLGESEVRRANALRPHEEYHILFISNVLDPDKMRLRVLPNPFSVGGLASYQVVGRSLNLRFRSAD
>NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein
MMTKHPSNSDLPHEGDLNHGEERDRLTRPAVRPIPKWVVVTGVPLMMVIAISAAWLLLSTGATRDQLDALRTAGTLGVGFGGVVALWLAVRRQRSTEHDLLQKYQAHELAERVAAQNQAAADRAAAHAEHDARERRLTDLYLKAVEHLGSAHAPVRHGGLYALERVAQDNPSQRQTVVDVVCAYLRAPYTPPNTSRASRLGLKRPLQSSTRSRATNSARARETTTTSAHTRTISASLEEREVRMTAQRLLKRHLSLDIHDNSTGLFWDNIDLDLAGATLVSFDFRGCRVKHCTFLHSTFVGPARFDNAVFTGEASFARSAFTAEARFSGATFANETWFKGATFTDGPIFNGTTFSGEYFFQEVNFAGNAQFDGTLFTEGTPVEVSAHLDGQSRSASP
>NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein
MAFPNRWTASSSAAAALANSPTRRIREVQRIEQGMGRGVRDSDDHCAVLLVGSKLAMATRDPDWKKLFSPATRAQLDLSNQVAVQLKGQGLDAVRSALTACLDRDPNWVERSRRALAEIRYLDAGTIRPEAIAIRAAFDLASAGQYSAAADEIQRAINGIEDTLLRTEGQLPAPRHPPSSPSSSKASPSRRTERCSSRWSE
>NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase
MDDVEKWCPEPLWLLAQPLLPEAPQRHQGGGRRRLDDRVVLAAILYVLQTGCAWSALPASFGVSAPTAHRRFTEWVETEVFARLHQAVLDLLGSAGAIDWSRASVDGMHVRAVKGGDLTGPSPVDRGKRGSKIHAISDRSGLPLAVGVSAANRNDHLELEAVVDAVVPVKGPAGRPRRRPRKLHADKGYDYPTCRKALRRRGIIARIARRGIESPKRLGRHRYVIERTLEWVSRFRRLARRYERKAAHFTAFTQLACAVICYRRAIKLDLLTHNNPK
>NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein
MLGINATLADIEWDEDRTPQAEAAWERLGSHLGFTSTRPEKLYGKGPDNLWALAGDRHAVVEMKTGCTTDMIAKKDVDQLGGSVRWDQDNHPGITSIPGITSIPIMVHPSRIVNHQGTPVPGMRVITAAKLDELKTAVRSFAVALADGQGRWYDEQGVSVQLTQARLTAGKFLNAFTEVNLVES
>NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein
MSPRERDAHELRQLARETADQLASFAHIFSAADRRNDRVTPPELFTLAGLLEDAAAVLGEDARVKPLIFSFKDTIVPQKELNFDIAYRYLTPIVRAIRSRYNLPGSPHASPASKPRRRVDVRIDTDRHDRAQSDGDRDSGT
>NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein
MSLTDEQWDALGLDRVVVRDRAEFFIGYAGSEAPLFDVDGVIDAFRDGPLGDETDQKVAKFTDTDDAGPAGLLRRRMAEAAGRPGRRPWARTAERADALRHAAQAALLGDTREGRNLLLQSASLYRELGLPFGDFLSAAAVGPGDAAFEAAGQLRSIIFGSETAPEARRVDEGYFSLPRRLLAPAQQIAVLFTALSSADGVDGFGIGIDLLRRASQATQATSVGVTGRPVALWWECGVRLAELTYGRPSARDDLRTTIAELATAHGQALRTAQFDRYHWPRALSKMDLVDLDLTGLTAISNRVLRQLGEPEWSMFEDFRDLTPLSQVSVQVGIRLSGPGRPRTPASGPSPSPEPTPGPAAASDYVPESRSPSLWARS
>NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein
MIVQWCCKGMAKLPEREAERILTGGTGIRCRSWLTVAPKPFPLGKNLDRLTEDNLDRHVNKYSDPDPVTGAPFHDVTPFISLSAGCVDRQVAIERNETHSALRTALTFATTDYSQPGPNWPRCAGWVFYCYVLTGVNRAVSIPSVAEEYRELNLGRSYSRWQPQGEVMAKINVPSRQILCAVHWTPLPSGESKWDEVLWNLRFTHPAALLGERNML
>NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein
MEIAKLIVAALTPLSVALIGVVLTRSMRRLEHSNWLNQKLIEKRIEVLGEALPKLNDLYCYFSWIGTWASLSPVDVLQRKRDLDRLFHANRAFFTSSAFDVYGAFIDLLFETYAQPGKGARLRTEMTSHNGNRADVYPKKWEEGWSEMFSGVPRTSSLLTVKKCYEGLVMTFSAEVGIERSDAVGR
>NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease
MRKTVRVLPDMDRWRQLISEYGQLQQLTGHTPQTRGQRFNNMIAELLQCWGIQATANVRAAGEIDVAFAIDGVRFVVEAKWEKTKADTGRIAKLQKRVRQRLSGTYGVFLSMSGYSPEALDDIADGDRLEVLLLSIEHWEAMLGGLVPPQELFNLVRDRASFYGEPYTPLAQLFAPAEIPDIRLGPPSEMTDGPLLEAVDGLDAQVVLSGIESGQLGIACHGQNSLLVTTEHGILDVDFEAHTVTMAAPVPDCQRNVLANEDGSIVFLRRSGVGLFRDGQITTVGGGLSGNSCLCRHPDGSLWVFDNGGLLDHSASVTRLDDKLGLQKRHKINYSPANAFTSA
>NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein
MLRLFDAPVYRDWLFWFMLAWAALDFVSVLTLGPPSGLPRWLTALIGAAFFALVCGLVPAWIRLRLRRRRHGHGRMATKER
>NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MFLSKLTINVHSRTFRRDYANVHDMHRTLMSVYPDVPADTPKRQAHGVLWRLDSNRGSYVQYVQSHTRPDWDKLPDGHLNAPAEIRPLQPVLDAITAGRKLAFRFVANPTRCDNKTRQRIPLRQPADQIDWLIRQGQTHGFVIPATAAGPDIAITPTATITGRKSEPSKITIEPVRFDGHLIVTDPAAFTDAFSNGIGRAKAYGCGLISLAPSRTL
>NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTHTLALCFDAPMQSWGLRSRGILRDTAREPTKSGVVGLLAAATGVERDDEAGIATLAALRLGVRVDREGLLERDYHTTQNVPTTTGSGHRTVVSERYYLADALFLVAIEGPETLLSELADAVTNPRWPLFFGRRAFVSARPLFDDGLHAGNLEQILREHRWLEHPDRAGAMIPGQQQIALRTVVDCPTGTVGAEPRHDVPRSFAHGARSFATRTVLVGEVPLTDNMIPAGDTTCS
>NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MIIELHLLQSFPVSNLNRDDVGQPKTATFGGSTRGRISSQCLKRSARQLFTDHGLTDTETGIRTKRLRNEAAALLTKRGRDEQEAAGVVTAGLEQLGFGVDQDKGLTEYLLFVGTTAIEHLAGYCDDRWDTLAAVAAAKDGKKKPAKAKPDKNDLAEAKRMLDATRVADVALFGRMIADNKDFNVDAASQVAHALSTHAVATEFDYYTAVDDLKPEAESGADMIGTVDFNAACYYRYANLDLDRLRQNLAGDDELVARAARAWLGAFIHAVPSGKQNSMAARTMPDTLLGVVRDGGAWNLANAFLKPVTGEDIMAASTASLTQHFQQLRAFYGSSSIRAAVAASVTGQLPDMDGTDTAASIDEFTSRILAAGTTPA
>NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSTPVAQRRDGFISALYALNAGLESSIPKRRSEARQVLARLRRSLVTARPEPAAYEVVFRHDPPESEQDAWILVAGLFALHPKASRRGDRSIGTAMQALQDKRGDSATRRFEQLLGRDRAGLPHHLRQIVRLLAAEGIPVNYAALLDDLVVLMGDKYSEDTAHRIRLRWARDFHRKRKTTTTDNGEPAPAPTTVENPA
>NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSATFDLTTESWIPVVYLDEPDGAETLVGLRELFSSAHRIRRIVGETPPMTAALYRLALAILHRAYGPARLPEWEKLWTTETFAPALLAAYLDRPGLSFDLFDLQRPFLQCPGLPEGKKSTVAKLIPHRAVGNRVTLFDHTTAQDRVELTPAAAARWLVTAQAFDPGGMKTPYKTDKSSERAPCNYFGVVLVEGANLKETLLLNAVRYDAQASDDAPAWEAPTPSPEPDKRRSRGWTDVLTWPSRRICLLPEHTNGATVVANAVLTPGTRLVGERPEIERMAAYRTPRTPSGKPKPDAPMLPIRLQPVRGVWRHSVELLLVDPWSEERTRLRPQALKQLATLAEHGSIPADTVYTLRVFGQRLDANASVVEAYLEEEVPAPVALIRAGDDALTGLVGCAIELAEEAGAALRAMQREYHKDMRAEPDVTLDLAYWPALPTPFAAFLRALNDARLAGQSEQRAMAGWRRAVTSVAEQAADSWAAGIAADGRSLNMIGKHLGAVLDRLRTIARTYDAQIAKYLTKDGHE
>NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein
MTGGDDELAELSVRVVLYRRDQDGELKPVYPDSDGLLESATVLAAPINVPAAVVRALLDSEVPADFAADPWLNRHRALVFTDGQCRVAGYELRYHDKFGVYASEET
>NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3
MLDTAAVAERLAPLLLRGRVRSELAAAFGVLGDAWGWTAFLCAVHDLGKYSPTFQALNFPLSSARLGSWAVRDLELVAKLHGVPRRVDTPHGLLTALHLQELLVSWGASRRTAVMIAAALGGHHGHFPAGEVVAQARREINAHGERVWAEQRTTLVAELARLRGLPDPRTLDWAQVDLSVPAAVGLAALTTVSDWIASDTSNFAFAEDEVDLAAYAKDAAVQAEAAVDRLKMSSWSPPGGARFDELFGQSPRSVQEVIERVTADLEGSALVVVEAPTGEGKTKAALQATATMVSQFGLAGSYLGMPTQATSNQMFAVMQAMLTRLGDPTTVSLVHSAAREVLAEPAEVGVDEPGTLDAEAQAWFTRKRSLLSVLGCGTIDQALKGAFRSGHVFVRLAGLANKVVVFDEVHAYDTYMSTLLQRLLMWLGALGAPVVLLSATLPSSRRAELIAAWQAGYRGCYPQEINVPPASKPYPRVTVADTAEVVDHPVEISELNRDRVVHLEHVPDERVVDWLLVAAQGRCVAVVHNLVRRATETYAELERRIKELPEEDRPVLLAINGTLPTGARRRVEQELQGFFGENGMRPRRAIVVGTQAIEQSLDLDFDALITDLAPIDLVFQRAGRVHRHRRDAARGRLTVAITGVVDTPAGPQFPAYLRTVYAPIVLMRTWAALKDLDRIESWTTMAQLVDEVYGDQVACPRGWEAAWRRESDRLAVAQHNDREAAAESYLPQPHMVEVLSELTERPRALRTRKSTGRKR
>NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA

Crispr_ID: NC_017186_21

• CRISPR_ID: NC_017186_21
• CRISPR_location: 6441416-6441811
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 6 spacers
• Cas_protein_info: cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NC_017186_21

Consensus_repeat	Method
GTTGTCCCCGCACGCGCGGGGCTGGTCCC	CRISPRCasFinder
GTCGTCCCCGCGTACGCGGGGCTGGTCC	CRT

spacers of NC_017186_21

>21.1|6441445|32|NC_017186|CRISPRCasFinder
ACGATGCCGCGCTCGACGAACACCTCGTTCCC
>21.2|6441506|32|NC_017186|CRISPRCasFinder
TCGGCCAGCACCCGGCGGAGGTTCCGGATACT
>21.3|6441567|32|NC_017186|CRISPRCasFinder
ATCGATTCGCTGAGGACCTCCGGCAGCACGAT
>21.4|6441628|32|NC_017186|CRISPRCasFinder
GTGAAGGGCCTCTCCCCGGCCGGGCAGCGGTA
>21.5|6441689|32|NC_017186|CRISPRCasFinder
CACACCGGCAAGCCCGAGGCGATCCTCACGCA
>21.6|6441750|32|NC_017186|CRISPRCasFinder
GACACGACGGCGAGCCGGTCGTCGCGTTCCTT
>21.7|6441444|33|NC_017186|CRT
CACGATGCCGCGCTCGACGAACACCTCGTTCCC
>21.8|6441505|33|NC_017186|CRT
CTCGGCCAGCACCCGGCGGAGGTTCCGGATACT
>21.9|6441566|33|NC_017186|CRT
GATCGATTCGCTGAGGACCTCCGGCAGCACGAT
>21.10|6441627|33|NC_017186|CRT
GGTGAAGGGCCTCTCCCCGGCCGGGCAGCGGTA
>21.11|6441688|33|NC_017186|CRT
CCACACCGGCAAGCCCGAGGCGATCCTCACGCA
>21.12|6441749|33|NC_017186|CRT
CGACACGACGGCGAGCCGGTCGTCGCGTTCCTT

CRISPR arrays and Neighbor proteins around NC_017186_21

CRISPR arrays

The CRISPR arrays of NC_017186_21

>merge|NC_017186|21|6441416-6441811|CRISPRCasFinder,CRT
GTTATCCCCGCACGCGCGGGGCTGGTCCCACGATGCCGCGCTCGACGAACACCTCGTTCCCGTCGTCCCCGCGTACGCGGGGCTGGTCCCTCGGCCAGCACCCGGCGGAGGTTCCGGATACTGTCGTCCCCACGTACGCGGGGCTGGTCCGATCGATTCGCTGAGGACCTCCGGCAGCACGATGTCGTCCCCGCGCACCTGGGGCTGGTCCGGTGAAGGGCCTCTCCCCGGCCGGGCAGCGGTAGTCGTCCCCGCGTACGCGGGGCTGGTCCCCACACCGGCAAGCCCGAGGCGATCCTCACGCAGTCGTCCCTGCGTTCGCGGGGCTGGTCCCGACACGACGGCGAGCCGGTCGTCGCGTTCCTTGTCGTCCCCGCGTACGCGGGGCTCCTCCCA

>NC_017186|21|20|6441416-6441811|CRISPRCasFinder
GTTATCCCCGCACGCGCGGGGCTGGTCCC	ACGATGCCGCGCTCGACGAACACCTCGTTCCC
GTCGTCCCCGCGTACGCGGGGCTGGTCCC	TCGGCCAGCACCCGGCGGAGGTTCCGGATACT
GTCGTCCCCACGTACGCGGGGCTGGTCCG	ATCGATTCGCTGAGGACCTCCGGCAGCACGAT
GTCGTCCCCGCGCACCTGGGGCTGGTCCG	GTGAAGGGCCTCTCCCCGGCCGGGCAGCGGTA
GTCGTCCCCGCGTACGCGGGGCTGGTCCC	CACACCGGCAAGCCCGAGGCGATCCTCACGCA
GTCGTCCCTGCGTTCGCGGGGCTGGTCCC	GACACGACGGCGAGCCGGTCGTCGCGTTCCTT
GTCGTCCCCGCGTACGCGGGGCTCCTCCCA

>NC_017186|21|5|6441416-6441809|CRT
GTTATCCCCGCACGCGCGGGGCTGGTCC	CACGATGCCGCGCTCGACGAACACCTCGTTCCC
GTCGTCCCCGCGTACGCGGGGCTGGTCC	CTCGGCCAGCACCCGGCGGAGGTTCCGGATACT
GTCGTCCCCACGTACGCGGGGCTGGTCC	GATCGATTCGCTGAGGACCTCCGGCAGCACGAT
GTCGTCCCCGCGCACCTGGGGCTGGTCC	GGTGAAGGGCCTCTCCCCGGCCGGGCAGCGGTA
GTCGTCCCCGCGTACGCGGGGCTGGTCC	CCACACCGGCAAGCCCGAGGCGATCCTCACGCA
GTCGTCCCTGCGTTCGCGGGGCTGGTCC	CGACACGACGGCGAGCCGGTCGTCGCGTTCCTT
GTCGTCCCCGCGTACGCGGGGCTCCTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|378243
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	unknown	unknown	gnl|CDD|375821
NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|379021
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|379274

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.9e-55	182.0	0.0
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	1.5e-46	153.2	0.3
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	3e-31	103.3	3.9
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.9e-59	195.7	0.0
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	2.3e-96	318.3	3.8
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	5e-111	366.4	1.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.80328e-21
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.75313e-78
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.02918e-12
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.56766e-47
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	7.65375e-42
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	gnl|CDD|375821	pfam18395, Cas3_C, Cas3 C-terminal domain. This is the C-temrinal domain of Cas3 proteins. The C-terminal domain (CTD) is shown to completely wrap ssDNA inside the helicase. Deletion of the CTD (aa 819-924) reduced CRISPR interference. It is suggested that the CTD regulates the N-terminal HD nuclease activity by functioning as a substrate filter.	5.47198e-09
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	0.00914745
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	gnl|CDD|379021	pfam13020, DUF3883, Domain of unknown function (DUF3883). This is a domain is uncharacterized. It is found on restriction endonucleases.	1.15745e-05
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.44632e-24
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	gnl|CDD|379274	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies).	1.9456e-07
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.53205e-80
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	9.17843e-107
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	9.95055e-141

Protein sequences

>NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase
MDRGTEAWLRSLTFDRVGVRLAFEEAFDAVLATRAQRARLDAAITELAAPPVFAPVMGRLACLHGVSTLTAFGLVTEIGDWRRFTGASIGAYVSLVPADSSSGEHRHQGAITKTGNSDGQRLLVEAA
>NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein
MIEEPVELAKDLTRLVLQQADSVVAMYLAGAKYEQPVTREQKESIESIIAADYDGRTVVELLQNGHDAHDSGRSDGKLEFLLDENEGAHGVLYAANGGRPLDQENFRSMCLIARSSKRPDEGIGNKGVGFKSVLQLSDCPEVYSARHEGAGRFDGFRFRFGRPDDFDGLAARSKENWPGLADELRENVSTLKITVPLFETPTVVEDFARRGYSTVVRLPLRSASTRDHARDQLEELAHDEVPFHLFLTRVAEIVVRSQAGETESRRRLTRSTRARRGTSTLSVEHIDLGEQREYVILKRVVAETGIRAAIRASLDDNAIGSGWAGWQGAAEVSVAVPLGAALSQGRVYTFLPLGPGSPCPIAALVNGPFFTRLDRRDVHESIPLNDFLFAEIAALCADAVVAACRGDLELPDEVPLDLVCWAPGWTQRLIAALQALGVELVDLPVLPPLQHQGEGLTFKSALLWSYRGAVFTPEAVTAAGETRLIRYSIDEQRLRRLRKLAKATDHPVEARPADLAGFAETLADDLLRRGESYEVWAGFYDDLSVVLTDVTLIRGHRVFLTEGGILRTSIEDDDLMIYFGPVRGEAGELPELPEVVRDRLAFMPADINWSDERGQRPGRRWLEAIVREYRTDAVLDLIGKVMYDTEAEEVRSACLRFAFDLWQDTPAERRATALGRAGLLVRTRSGWKAPAEAYFDAGWGGPAGKIDRQLADLVKATALISGTLAAVGQSLLFKPELGEATLDDVRTFFEALGVRHGLVPLTVRASRFQLQGKTLKNPRTVPVFPIEISVATQAAWRELAARHSGKPSYDSTRYQPAGGIAYLPGQEEWSEFDDTARRLYFQLVLHGLEVWPATTLWTYFQASSDSVRVTWPTFVAAFLVRADWIPQTTPGDRGKQFFRPMSDAWWVGNTDTPDYLSADPAAFRSLLTDRVRVHLQRLGARFWDDPGTAADRLRELTSVVRLRGPRMSLVRNAYEQAWRDLADRGEEVPHEVIVSVHGSLGVLDLDQEGPAVYTLDEDGAVQAALLIQTPLPMLAVRSPGVAERVRQTLVSDGVSRLRAASAATVQVLADGTDPLTMKSQPLTDLGGDWLPLLVDAIADRRRQALPAAGITVGATAGALRDSVGLVLADSITAVIDGHPVDQEFAPSSMRVVSPEGDPVIVALRGTGEPWVVLQSAAAALAEFRGGPPIADSVRLALIDLTQRCGDRTPTLDDLAVVLKLPVTELQSLAGDAASTRFEVTPVLGLLACLDPGIAEELQGDRIGDQQEMLDWLSRRGFDADEILALAGQNDLLDATRQLDIPLAQANAGLRAVNLPLLHNDIGHRQQFDAYLQRHRPELQDQLRDRFVARFRRGEPLDEYLRLRDLPGLEPDSTWLDTYWHLPDHVVQARLDLWLASVGEPLAGKDRLPPVDELRDRGRRAVMRTLERARIVIEAWLQRNTAGTGARPAEIAGTLEKMVQTGFLDFEVPRTSAVVVWLGEHGQWPVGMPATTEPRQLDLTDGDLKAAESRLNAGHDTAKRRTETVRYAGKTYSTGTEDRDSLIRAVRESVPQGVLDTSATADRMAPLPPSSSAVSGSSSGEWRAPVLSAEKTRLIGLAGEIVAGEWLNAKFGLQPEDTWVSGYRAEYLADGKGNDSCGYDFLVTLPDRTLLYEVKATTDNARQFTLGESEVRRANALRPHEEYHILFISNVLDPDKMRLRVLPNPFSVGGLASYQVVGRSLNLRFRSAD
>NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein
MMTKHPSNSDLPHEGDLNHGEERDRLTRPAVRPIPKWVVVTGVPLMMVIAISAAWLLLSTGATRDQLDALRTAGTLGVGFGGVVALWLAVRRQRSTEHDLLQKYQAHELAERVAAQNQAAADRAAAHAEHDARERRLTDLYLKAVEHLGSAHAPVRHGGLYALERVAQDNPSQRQTVVDVVCAYLRAPYTPPNTSRASRLGLKRPLQSSTRSRATNSARARETTTTSAHTRTISASLEEREVRMTAQRLLKRHLSLDIHDNSTGLFWDNIDLDLAGATLVSFDFRGCRVKHCTFLHSTFVGPARFDNAVFTGEASFARSAFTAEARFSGATFANETWFKGATFTDGPIFNGTTFSGEYFFQEVNFAGNAQFDGTLFTEGTPVEVSAHLDGQSRSASP
>NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein
MAFPNRWTASSSAAAALANSPTRRIREVQRIEQGMGRGVRDSDDHCAVLLVGSKLAMATRDPDWKKLFSPATRAQLDLSNQVAVQLKGQGLDAVRSALTACLDRDPNWVERSRRALAEIRYLDAGTIRPEAIAIRAAFDLASAGQYSAAADEIQRAINGIEDTLLRTEGQLPAPRHPPSSPSSSKASPSRRTERCSSRWSE
>NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase
MDDVEKWCPEPLWLLAQPLLPEAPQRHQGGGRRRLDDRVVLAAILYVLQTGCAWSALPASFGVSAPTAHRRFTEWVETEVFARLHQAVLDLLGSAGAIDWSRASVDGMHVRAVKGGDLTGPSPVDRGKRGSKIHAISDRSGLPLAVGVSAANRNDHLELEAVVDAVVPVKGPAGRPRRRPRKLHADKGYDYPTCRKALRRRGIIARIARRGIESPKRLGRHRYVIERTLEWVSRFRRLARRYERKAAHFTAFTQLACAVICYRRAIKLDLLTHNNPK
>NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein
MLGINATLADIEWDEDRTPQAEAAWERLGSHLGFTSTRPEKLYGKGPDNLWALAGDRHAVVEMKTGCTTDMIAKKDVDQLGGSVRWDQDNHPGITSIPGITSIPIMVHPSRIVNHQGTPVPGMRVITAAKLDELKTAVRSFAVALADGQGRWYDEQGVSVQLTQARLTAGKFLNAFTEVNLVES
>NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein
MSPRERDAHELRQLARETADQLASFAHIFSAADRRNDRVTPPELFTLAGLLEDAAAVLGEDARVKPLIFSFKDTIVPQKELNFDIAYRYLTPIVRAIRSRYNLPGSPHASPASKPRRRVDVRIDTDRHDRAQSDGDRDSGT
>NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein
MSLTDEQWDALGLDRVVVRDRAEFFIGYAGSEAPLFDVDGVIDAFRDGPLGDETDQKVAKFTDTDDAGPAGLLRRRMAEAAGRPGRRPWARTAERADALRHAAQAALLGDTREGRNLLLQSASLYRELGLPFGDFLSAAAVGPGDAAFEAAGQLRSIIFGSETAPEARRVDEGYFSLPRRLLAPAQQIAVLFTALSSADGVDGFGIGIDLLRRASQATQATSVGVTGRPVALWWECGVRLAELTYGRPSARDDLRTTIAELATAHGQALRTAQFDRYHWPRALSKMDLVDLDLTGLTAISNRVLRQLGEPEWSMFEDFRDLTPLSQVSVQVGIRLSGPGRPRTPASGPSPSPEPTPGPAAASDYVPESRSPSLWARS
>NC_017186.1|WP_014467353.1|6423865_6424516_+|hypothetical-protein
MIVQWCCKGMAKLPEREAERILTGGTGIRCRSWLTVAPKPFPLGKNLDRLTEDNLDRHVNKYSDPDPVTGAPFHDVTPFISLSAGCVDRQVAIERNETHSALRTALTFATTDYSQPGPNWPRCAGWVFYCYVLTGVNRAVSIPSVAEEYRELNLGRSYSRWQPQGEVMAKINVPSRQILCAVHWTPLPSGESKWDEVLWNLRFTHPAALLGERNML
>NC_017186.1|WP_013227603.1|6423308_6423869_+|hypothetical-protein
MEIAKLIVAALTPLSVALIGVVLTRSMRRLEHSNWLNQKLIEKRIEVLGEALPKLNDLYCYFSWIGTWASLSPVDVLQRKRDLDRLFHANRAFFTSSAFDVYGAFIDLLFETYAQPGKGARLRTEMTSHNGNRADVYPKKWEEGWSEMFSGVPRTSSLLTVKKCYEGLVMTFSAEVGIERSDAVGR
>NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease
MRKTVRVLPDMDRWRQLISEYGQLQQLTGHTPQTRGQRFNNMIAELLQCWGIQATANVRAAGEIDVAFAIDGVRFVVEAKWEKTKADTGRIAKLQKRVRQRLSGTYGVFLSMSGYSPEALDDIADGDRLEVLLLSIEHWEAMLGGLVPPQELFNLVRDRASFYGEPYTPLAQLFAPAEIPDIRLGPPSEMTDGPLLEAVDGLDAQVVLSGIESGQLGIACHGQNSLLVTTEHGILDVDFEAHTVTMAAPVPDCQRNVLANEDGSIVFLRRSGVGLFRDGQITTVGGGLSGNSCLCRHPDGSLWVFDNGGLLDHSASVTRLDDKLGLQKRHKINYSPANAFTSA
>NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein
MLRLFDAPVYRDWLFWFMLAWAALDFVSVLTLGPPSGLPRWLTALIGAAFFALVCGLVPAWIRLRLRRRRHGHGRMATKER
>NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MFLSKLTINVHSRTFRRDYANVHDMHRTLMSVYPDVPADTPKRQAHGVLWRLDSNRGSYVQYVQSHTRPDWDKLPDGHLNAPAEIRPLQPVLDAITAGRKLAFRFVANPTRCDNKTRQRIPLRQPADQIDWLIRQGQTHGFVIPATAAGPDIAITPTATITGRKSEPSKITIEPVRFDGHLIVTDPAAFTDAFSNGIGRAKAYGCGLISLAPSRTL
>NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTHTLALCFDAPMQSWGLRSRGILRDTAREPTKSGVVGLLAAATGVERDDEAGIATLAALRLGVRVDREGLLERDYHTTQNVPTTTGSGHRTVVSERYYLADALFLVAIEGPETLLSELADAVTNPRWPLFFGRRAFVSARPLFDDGLHAGNLEQILREHRWLEHPDRAGAMIPGQQQIALRTVVDCPTGTVGAEPRHDVPRSFAHGARSFATRTVLVGEVPLTDNMIPAGDTTCS
>NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MIIELHLLQSFPVSNLNRDDVGQPKTATFGGSTRGRISSQCLKRSARQLFTDHGLTDTETGIRTKRLRNEAAALLTKRGRDEQEAAGVVTAGLEQLGFGVDQDKGLTEYLLFVGTTAIEHLAGYCDDRWDTLAAVAAAKDGKKKPAKAKPDKNDLAEAKRMLDATRVADVALFGRMIADNKDFNVDAASQVAHALSTHAVATEFDYYTAVDDLKPEAESGADMIGTVDFNAACYYRYANLDLDRLRQNLAGDDELVARAARAWLGAFIHAVPSGKQNSMAARTMPDTLLGVVRDGGAWNLANAFLKPVTGEDIMAASTASLTQHFQQLRAFYGSSSIRAAVAASVTGQLPDMDGTDTAASIDEFTSRILAAGTTPA
>NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSTPVAQRRDGFISALYALNAGLESSIPKRRSEARQVLARLRRSLVTARPEPAAYEVVFRHDPPESEQDAWILVAGLFALHPKASRRGDRSIGTAMQALQDKRGDSATRRFEQLLGRDRAGLPHHLRQIVRLLAAEGIPVNYAALLDDLVVLMGDKYSEDTAHRIRLRWARDFHRKRKTTTTDNGEPAPAPTTVENPA
>NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSATFDLTTESWIPVVYLDEPDGAETLVGLRELFSSAHRIRRIVGETPPMTAALYRLALAILHRAYGPARLPEWEKLWTTETFAPALLAAYLDRPGLSFDLFDLQRPFLQCPGLPEGKKSTVAKLIPHRAVGNRVTLFDHTTAQDRVELTPAAAARWLVTAQAFDPGGMKTPYKTDKSSERAPCNYFGVVLVEGANLKETLLLNAVRYDAQASDDAPAWEAPTPSPEPDKRRSRGWTDVLTWPSRRICLLPEHTNGATVVANAVLTPGTRLVGERPEIERMAAYRTPRTPSGKPKPDAPMLPIRLQPVRGVWRHSVELLLVDPWSEERTRLRPQALKQLATLAEHGSIPADTVYTLRVFGQRLDANASVVEAYLEEEVPAPVALIRAGDDALTGLVGCAIELAEEAGAALRAMQREYHKDMRAEPDVTLDLAYWPALPTPFAAFLRALNDARLAGQSEQRAMAGWRRAVTSVAEQAADSWAAGIAADGRSLNMIGKHLGAVLDRLRTIARTYDAQIAKYLTKDGHE
>NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein
MTGGDDELAELSVRVVLYRRDQDGELKPVYPDSDGLLESATVLAAPINVPAAVVRALLDSEVPADFAADPWLNRHRALVFTDGQCRVAGYELRYHDKFGVYASEET
>NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3
MLDTAAVAERLAPLLLRGRVRSELAAAFGVLGDAWGWTAFLCAVHDLGKYSPTFQALNFPLSSARLGSWAVRDLELVAKLHGVPRRVDTPHGLLTALHLQELLVSWGASRRTAVMIAAALGGHHGHFPAGEVVAQARREINAHGERVWAEQRTTLVAELARLRGLPDPRTLDWAQVDLSVPAAVGLAALTTVSDWIASDTSNFAFAEDEVDLAAYAKDAAVQAEAAVDRLKMSSWSPPGGARFDELFGQSPRSVQEVIERVTADLEGSALVVVEAPTGEGKTKAALQATATMVSQFGLAGSYLGMPTQATSNQMFAVMQAMLTRLGDPTTVSLVHSAAREVLAEPAEVGVDEPGTLDAEAQAWFTRKRSLLSVLGCGTIDQALKGAFRSGHVFVRLAGLANKVVVFDEVHAYDTYMSTLLQRLLMWLGALGAPVVLLSATLPSSRRAELIAAWQAGYRGCYPQEINVPPASKPYPRVTVADTAEVVDHPVEISELNRDRVVHLEHVPDERVVDWLLVAAQGRCVAVVHNLVRRATETYAELERRIKELPEEDRPVLLAINGTLPTGARRRVEQELQGFFGENGMRPRRAIVVGTQAIEQSLDLDFDALITDLAPIDLVFQRAGRVHRHRRDAARGRLTVAITGVVDTPAGPQFPAYLRTVYAPIVLMRTWAALKDLDRIESWTTMAQLVDEVYGDQVACPRGWEAAWRRESDRLAVAQHNDREAAAESYLPQPHMVEVLSELTERPRALRTRKSTGRKR
>NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA

Crispr_ID: NC_017186_24

• CRISPR_ID: NC_017186_24
• CRISPR_location: 6444797-6444943
• CRISPR_type: TypeI-E
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas6e,cas5,cas7,cse2gr11,cas8e,cas3

Consensus repeat of NC_017186_24

Consensus_repeat	Method
GTCGTCCCCTCGCAAGCGGGGCTG	CRISPRCasFinder

spacers of NC_017186_24

>24.1|6444821|37|NC_017186|CRISPRCasFinder
GTCCGAGCTCCGTCCGGGTTATGAACGAGTTCGGCTT
>24.2|6444882|38|NC_017186|CRISPRCasFinder
GCCCTGCGCTCTCGCGTCGCAGACCGTCATCTCCGATC

CRISPR arrays and Neighbor proteins around NC_017186_24

CRISPR arrays

The CRISPR arrays of NC_017186_24

>merge|NC_017186|24|6444797-6444943|CRISPRCasFinder
GTCGTCCCCGCGCAAACAGGACTGGTCCGAGCTCCGTCCGGGTTATGAACGAGTTCGGCTTGGTATCCCCGCGCGGGTGGGGCTGGCCCTGCGCTCTCGCGTCGCAGACCGTCATCTCCGATCGCCCCCACCTCGCAGGCGGAGCTG

>NC_017186|24|23|6444797-6444943|CRISPRCasFinder
GTCGTCCCCGCGCAAACAGGACTG	GTCCGAGCTCCGTCCGGGTTATGAACGAGTTCGGCTT
GGTATCCCCGCGCGGGTGGGGCTG	GCCCTGCGCTCTCGCGTCGCAGACCGTCATCTCCGATC
GCCCCCACCTCGCAGGCGGAGCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	unknown	unknown	gnl|CDD|379129
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl|CDD|378050
NC_017186.1|WP_013223344.1|6453920_6454244_-|IS3-family-transposase	unknown	unknown	gnl|CDD|225511
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376773
NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	unknown	unknown	gnl|CDD|222853
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl|CDD|378243
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	unknown	unknown	gnl|CDD|375821
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|379021
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl|CDD|378191
NC_017186.1|WP_013227617.1|6454593_6456450_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl|CDD|378153
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|182031
NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl|CDD|378189
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|379274

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	3.9e-55	182.0	0.0
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	1.5e-46	153.2	0.3
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	3e-31	103.3	3.9
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	2.9e-59	195.7	0.0
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	2.3e-96	318.3	3.8
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	5e-111	366.4	1.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.80328e-21
NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl|CDD|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	6.75313e-78
NC_017186.1|WP_013223344.1|6453920_6454244_-|IS3-family-transposase	gnl|CDD|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.26793e-07
NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase	gnl|CDD|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	3.02918e-12
NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase	gnl|CDD|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	5.56766e-47
NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl|CDD|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	7.65375e-42
NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein	gnl|CDD|375821	pfam18395, Cas3_C, Cas3 C-terminal domain. This is the C-temrinal domain of Cas3 proteins. The C-terminal domain (CTD) is shown to completely wrap ssDNA inside the helicase. Deletion of the CTD (aa 819-924) reduced CRISPR interference. It is suggested that the CTD regulates the N-terminal HD nuclease activity by functioning as a substrate filter.	5.47198e-09
NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	0.00914745
NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein	gnl|CDD|379021	pfam13020, DUF3883, Domain of unknown function (DUF3883). This is a domain is uncharacterized. It is found on restriction endonucleases.	1.15745e-05
NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl|CDD|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	2.44632e-24
NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein	gnl|CDD|379274	pfam13576, Pentapeptide_3, Pentapeptide repeats (9 copies).	1.9456e-07
NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.53205e-80
NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl|CDD|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	9.17843e-107
NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl|CDD|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	9.95055e-141

Protein sequences

>NC_017186.1|WP_014467360.1|6443991_6444237_+|hypothetical-protein
MLRLFDAPVYRDWLFWFMLAWAALDFVSVLTLGPPSGLPRWLTALIGAAFFALVCGLVPAWIRLRLRRRRHGHGRMATKER
>NC_017186.1|WP_013227609.1|6442309_6443341_+|restriction-endonuclease
MRKTVRVLPDMDRWRQLISEYGQLQQLTGHTPQTRGQRFNNMIAELLQCWGIQATANVRAAGEIDVAFAIDGVRFVVEAKWEKTKADTGRIAKLQKRVRQRLSGTYGVFLSMSGYSPEALDDIADGDRLEVLLLSIEHWEAMLGGLVPPQELFNLVRDRASFYGEPYTPLAQLFAPAEIPDIRLGPPSEMTDGPLLEAVDGLDAQVVLSGIESGQLGIACHGQNSLLVTTEHGILDVDFEAHTVTMAAPVPDCQRNVLANEDGSIVFLRRSGVGLFRDGQITTVGGGLSGNSCLCRHPDGSLWVFDNGGLLDHSASVTRLDDKLGLQKRHKINYSPANAFTSA
>NC_017186.1|WP_013227607.1|6437865_6438249_+|IS110-family-transposase
MDRGTEAWLRSLTFDRVGVRLAFEEAFDAVLATRAQRARLDAAITELAAPPVFAPVMGRLACLHGVSTLTAFGLVTEIGDWRRFTGASIGAYVSLVPADSSSGEHRHQGAITKTGNSDGQRLLVEAA
>NC_017186.1|WP_013227606.1|6430525_6435712_-|DUF3883-domain-containing-protein
MIEEPVELAKDLTRLVLQQADSVVAMYLAGAKYEQPVTREQKESIESIIAADYDGRTVVELLQNGHDAHDSGRSDGKLEFLLDENEGAHGVLYAANGGRPLDQENFRSMCLIARSSKRPDEGIGNKGVGFKSVLQLSDCPEVYSARHEGAGRFDGFRFRFGRPDDFDGLAARSKENWPGLADELRENVSTLKITVPLFETPTVVEDFARRGYSTVVRLPLRSASTRDHARDQLEELAHDEVPFHLFLTRVAEIVVRSQAGETESRRRLTRSTRARRGTSTLSVEHIDLGEQREYVILKRVVAETGIRAAIRASLDDNAIGSGWAGWQGAAEVSVAVPLGAALSQGRVYTFLPLGPGSPCPIAALVNGPFFTRLDRRDVHESIPLNDFLFAEIAALCADAVVAACRGDLELPDEVPLDLVCWAPGWTQRLIAALQALGVELVDLPVLPPLQHQGEGLTFKSALLWSYRGAVFTPEAVTAAGETRLIRYSIDEQRLRRLRKLAKATDHPVEARPADLAGFAETLADDLLRRGESYEVWAGFYDDLSVVLTDVTLIRGHRVFLTEGGILRTSIEDDDLMIYFGPVRGEAGELPELPEVVRDRLAFMPADINWSDERGQRPGRRWLEAIVREYRTDAVLDLIGKVMYDTEAEEVRSACLRFAFDLWQDTPAERRATALGRAGLLVRTRSGWKAPAEAYFDAGWGGPAGKIDRQLADLVKATALISGTLAAVGQSLLFKPELGEATLDDVRTFFEALGVRHGLVPLTVRASRFQLQGKTLKNPRTVPVFPIEISVATQAAWRELAARHSGKPSYDSTRYQPAGGIAYLPGQEEWSEFDDTARRLYFQLVLHGLEVWPATTLWTYFQASSDSVRVTWPTFVAAFLVRADWIPQTTPGDRGKQFFRPMSDAWWVGNTDTPDYLSADPAAFRSLLTDRVRVHLQRLGARFWDDPGTAADRLRELTSVVRLRGPRMSLVRNAYEQAWRDLADRGEEVPHEVIVSVHGSLGVLDLDQEGPAVYTLDEDGAVQAALLIQTPLPMLAVRSPGVAERVRQTLVSDGVSRLRAASAATVQVLADGTDPLTMKSQPLTDLGGDWLPLLVDAIADRRRQALPAAGITVGATAGALRDSVGLVLADSITAVIDGHPVDQEFAPSSMRVVSPEGDPVIVALRGTGEPWVVLQSAAAALAEFRGGPPIADSVRLALIDLTQRCGDRTPTLDDLAVVLKLPVTELQSLAGDAASTRFEVTPVLGLLACLDPGIAEELQGDRIGDQQEMLDWLSRRGFDADEILALAGQNDLLDATRQLDIPLAQANAGLRAVNLPLLHNDIGHRQQFDAYLQRHRPELQDQLRDRFVARFRRGEPLDEYLRLRDLPGLEPDSTWLDTYWHLPDHVVQARLDLWLASVGEPLAGKDRLPPVDELRDRGRRAVMRTLERARIVIEAWLQRNTAGTGARPAEIAGTLEKMVQTGFLDFEVPRTSAVVVWLGEHGQWPVGMPATTEPRQLDLTDGDLKAAESRLNAGHDTAKRRTETVRYAGKTYSTGTEDRDSLIRAVRESVPQGVLDTSATADRMAPLPPSSSAVSGSSSGEWRAPVLSAEKTRLIGLAGEIVAGEWLNAKFGLQPEDTWVSGYRAEYLADGKGNDSCGYDFLVTLPDRTLLYEVKATTDNARQFTLGESEVRRANALRPHEEYHILFISNVLDPDKMRLRVLPNPFSVGGLASYQVVGRSLNLRFRSAD
>NC_017186.1|WP_080582935.1|6428988_6430182_+|pentapeptide-repeat-containing-protein
MMTKHPSNSDLPHEGDLNHGEERDRLTRPAVRPIPKWVVVTGVPLMMVIAISAAWLLLSTGATRDQLDALRTAGTLGVGFGGVVALWLAVRRQRSTEHDLLQKYQAHELAERVAAQNQAAADRAAAHAEHDARERRLTDLYLKAVEHLGSAHAPVRHGGLYALERVAQDNPSQRQTVVDVVCAYLRAPYTPPNTSRASRLGLKRPLQSSTRSRATNSARARETTTTSAHTRTISASLEEREVRMTAQRLLKRHLSLDIHDNSTGLFWDNIDLDLAGATLVSFDFRGCRVKHCTFLHSTFVGPARFDNAVFTGEASFARSAFTAEARFSGATFANETWFKGATFTDGPIFNGTTFSGEYFFQEVNFAGNAQFDGTLFTEGTPVEVSAHLDGQSRSASP
>NC_017186.1|WP_013227605.1|6427890_6428496_-|hypothetical-protein
MAFPNRWTASSSAAAALANSPTRRIREVQRIEQGMGRGVRDSDDHCAVLLVGSKLAMATRDPDWKKLFSPATRAQLDLSNQVAVQLKGQGLDAVRSALTACLDRDPNWVERSRRALAEIRYLDAGTIRPEAIAIRAAFDLASAGQYSAAADEIQRAINGIEDTLLRTEGQLPAPRHPPSSPSSSKASPSRRTERCSSRWSE
>NC_017186.1|WP_085931694.1|6426959_6427792_+|IS5-family-transposase
MDDVEKWCPEPLWLLAQPLLPEAPQRHQGGGRRRLDDRVVLAAILYVLQTGCAWSALPASFGVSAPTAHRRFTEWVETEVFARLHQAVLDLLGSAGAIDWSRASVDGMHVRAVKGGDLTGPSPVDRGKRGSKIHAISDRSGLPLAVGVSAANRNDHLELEAVVDAVVPVKGPAGRPRRRPRKLHADKGYDYPTCRKALRRRGIIARIARRGIESPKRLGRHRYVIERTLEWVSRFRRLARRYERKAAHFTAFTQLACAVICYRRAIKLDLLTHNNPK
>NC_017186.1|WP_013227604.1|6426349_6426904_-|hypothetical-protein
MLGINATLADIEWDEDRTPQAEAAWERLGSHLGFTSTRPEKLYGKGPDNLWALAGDRHAVVEMKTGCTTDMIAKKDVDQLGGSVRWDQDNHPGITSIPGITSIPIMVHPSRIVNHQGTPVPGMRVITAAKLDELKTAVRSFAVALADGQGRWYDEQGVSVQLTQARLTAGKFLNAFTEVNLVES
>NC_017186.1|WP_141748470.1|6425600_6426026_-|hypothetical-protein
MSPRERDAHELRQLARETADQLASFAHIFSAADRRNDRVTPPELFTLAGLLEDAAAVLGEDARVKPLIFSFKDTIVPQKELNFDIAYRYLTPIVRAIRSRYNLPGSPHASPASKPRRRVDVRIDTDRHDRAQSDGDRDSGT
>NC_017186.1|WP_014467354.1|6424512_6425646_+|hypothetical-protein
MSLTDEQWDALGLDRVVVRDRAEFFIGYAGSEAPLFDVDGVIDAFRDGPLGDETDQKVAKFTDTDDAGPAGLLRRRMAEAAGRPGRRPWARTAERADALRHAAQAALLGDTREGRNLLLQSASLYRELGLPFGDFLSAAAVGPGDAAFEAAGQLRSIIFGSETAPEARRVDEGYFSLPRRLLAPAQQIAVLFTALSSADGVDGFGIGIDLLRRASQATQATSVGVTGRPVALWWECGVRLAELTYGRPSARDDLRTTIAELATAHGQALRTAQFDRYHWPRALSKMDLVDLDLTGLTAISNRVLRQLGEPEWSMFEDFRDLTPLSQVSVQVGIRLSGPGRPRTPASGPSPSPEPTPGPAAASDYVPESRSPSLWARS
>NC_017186.1|WP_013227610.1|6444968_6445619_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MFLSKLTINVHSRTFRRDYANVHDMHRTLMSVYPDVPADTPKRQAHGVLWRLDSNRGSYVQYVQSHTRPDWDKLPDGHLNAPAEIRPLQPVLDAITAGRKLAFRFVANPTRCDNKTRQRIPLRQPADQIDWLIRQGQTHGFVIPATAAGPDIAITPTATITGRKSEPSKITIEPVRFDGHLIVTDPAAFTDAFSNGIGRAKAYGCGLISLAPSRTL
>NC_017186.1|WP_013227611.1|6445609_6446320_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MTHTLALCFDAPMQSWGLRSRGILRDTAREPTKSGVVGLLAAATGVERDDEAGIATLAALRLGVRVDREGLLERDYHTTQNVPTTTGSGHRTVVSERYYLADALFLVAIEGPETLLSELADAVTNPRWPLFFGRRAFVSARPLFDDGLHAGNLEQILREHRWLEHPDRAGAMIPGQQQIALRTVVDCPTGTVGAEPRHDVPRSFAHGARSFATRTVLVGEVPLTDNMIPAGDTTCS
>NC_017186.1|WP_013227612.1|6446316_6447447_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MIIELHLLQSFPVSNLNRDDVGQPKTATFGGSTRGRISSQCLKRSARQLFTDHGLTDTETGIRTKRLRNEAAALLTKRGRDEQEAAGVVTAGLEQLGFGVDQDKGLTEYLLFVGTTAIEHLAGYCDDRWDTLAAVAAAKDGKKKPAKAKPDKNDLAEAKRMLDATRVADVALFGRMIADNKDFNVDAASQVAHALSTHAVATEFDYYTAVDDLKPEAESGADMIGTVDFNAACYYRYANLDLDRLRQNLAGDDELVARAARAWLGAFIHAVPSGKQNSMAARTMPDTLLGVVRDGGAWNLANAFLKPVTGEDIMAASTASLTQHFQQLRAFYGSSSIRAAVAASVTGQLPDMDGTDTAASIDEFTSRILAAGTTPA
>NC_017186.1|WP_013227613.1|6447443_6448040_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSTPVAQRRDGFISALYALNAGLESSIPKRRSEARQVLARLRRSLVTARPEPAAYEVVFRHDPPESEQDAWILVAGLFALHPKASRRGDRSIGTAMQALQDKRGDSATRRFEQLLGRDRAGLPHHLRQIVRLLAAEGIPVNYAALLDDLVVLMGDKYSEDTAHRIRLRWARDFHRKRKTTTTDNGEPAPAPTTVENPA
>NC_017186.1|WP_013227614.1|6448036_6449617_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSATFDLTTESWIPVVYLDEPDGAETLVGLRELFSSAHRIRRIVGETPPMTAALYRLALAILHRAYGPARLPEWEKLWTTETFAPALLAAYLDRPGLSFDLFDLQRPFLQCPGLPEGKKSTVAKLIPHRAVGNRVTLFDHTTAQDRVELTPAAAARWLVTAQAFDPGGMKTPYKTDKSSERAPCNYFGVVLVEGANLKETLLLNAVRYDAQASDDAPAWEAPTPSPEPDKRRSRGWTDVLTWPSRRICLLPEHTNGATVVANAVLTPGTRLVGERPEIERMAAYRTPRTPSGKPKPDAPMLPIRLQPVRGVWRHSVELLLVDPWSEERTRLRPQALKQLATLAEHGSIPADTVYTLRVFGQRLDANASVVEAYLEEEVPAPVALIRAGDDALTGLVGCAIELAEEAGAALRAMQREYHKDMRAEPDVTLDLAYWPALPTPFAAFLRALNDARLAGQSEQRAMAGWRRAVTSVAEQAADSWAAGIAADGRSLNMIGKHLGAVLDRLRTIARTYDAQIAKYLTKDGHE
>NC_017186.1|WP_013227615.1|6449613_6449934_-|hypothetical-protein
MTGGDDELAELSVRVVLYRRDQDGELKPVYPDSDGLLESATVLAAPINVPAAVVRALLDSEVPADFAADPWLNRHRALVFTDGQCRVAGYELRYHDKFGVYASEET
>NC_017186.1|WP_013227616.1|6449930_6452210_-|CRISPR-associated-helicase/endonuclease-Cas3
MLDTAAVAERLAPLLLRGRVRSELAAAFGVLGDAWGWTAFLCAVHDLGKYSPTFQALNFPLSSARLGSWAVRDLELVAKLHGVPRRVDTPHGLLTALHLQELLVSWGASRRTAVMIAAALGGHHGHFPAGEVVAQARREINAHGERVWAEQRTTLVAELARLRGLPDPRTLDWAQVDLSVPAAVGLAALTTVSDWIASDTSNFAFAEDEVDLAAYAKDAAVQAEAAVDRLKMSSWSPPGGARFDELFGQSPRSVQEVIERVTADLEGSALVVVEAPTGEGKTKAALQATATMVSQFGLAGSYLGMPTQATSNQMFAVMQAMLTRLGDPTTVSLVHSAAREVLAEPAEVGVDEPGTLDAEAQAWFTRKRSLLSVLGCGTIDQALKGAFRSGHVFVRLAGLANKVVVFDEVHAYDTYMSTLLQRLLMWLGALGAPVVLLSATLPSSRRAELIAAWQAGYRGCYPQEINVPPASKPYPRVTVADTAEVVDHPVEISELNRDRVVHLEHVPDERVVDWLLVAAQGRCVAVVHNLVRRATETYAELERRIKELPEEDRPVLLAINGTLPTGARRRVEQELQGFFGENGMRPRRAIVVGTQAIEQSLDLDFDALITDLAPIDLVFQRAGRVHRHRRDAARGRLTVAITGVVDTPAGPQFPAYLRTVYAPIVLMRTWAALKDLDRIESWTTMAQLVDEVYGDQVACPRGWEAAWRRESDRLAVAQHNDREAAAESYLPQPHMVEVLSELTERPRALRTRKSTGRKR
>NC_017186.1|WP_158314388.1|6453003_6453834_-|IS3-family-transposase
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA
>NC_017186.1|WP_013223344.1|6453920_6454244_-|IS3-family-transposase
MPPRKRRSYPAEYKVEAAHRVIDSGRTIAEVARELGLDAGMLSVWVKDERRRVTAAEVHGENPLEAAERAELLRLRGQVAELEKDNAFLVKASAYFAAMQKNRPGSL
>NC_017186.1|WP_013227617.1|6454593_6456450_-|hypothetical-protein
MSDGDVMVFNGLSRFAVPVEKPVLLDDDGFLLATSDARWRSGEAVSPVPVAELPTEVVSFALLAAGGAGKTVTFTELANAEPDARRIDTSALTIDGLERELDDACFHESAVYLDGLDQAASVEARLFPWLERYLTAPARRGMRSRLACRAAAWDAVLGRALFQQMTAFTVWKLAPLDRDTASKAVEHAIGVSEVDSAAFMKALVGAKLGRLSGCVGQLVAVARYWNAQGVLPRSAADAMKFEIEYLLRETDERRQPRLPLDRSMRVAQRLGAFTMFAGNQALTVRAVGDRATLPVSDLPSDAEPDQPARTIEPLDYGAVLDTALFDSGPAGSVMFRHQRYLEYLAAAYLVQRGIRAGQIPVLLGVHVNGLLPTPRIGVASWLAALAPDLVAQLFIDNAAMFASAAAVVELPSDEARAALVKGLLEAAARDDAEPDWRLDRTGLLHAGLTEQLAEYLGRGPANAPQLWWIARLAAAGGCRTLAPALARAALEPAWFGYVRRAAVAAVADLGEDDLQLSLRQLLAEPTDTDPDADNEVRAAVIDALYPRLLSTVELTQALRPHRSMLFGGYLQSLRELPSRVPENDLADFVAWLADHAWRSDVRDDDQFEDLYAGVIKRA

Crispr_ID: NC_017186_25

• CRISPR_ID: NC_017186_25
• CRISPR_location: 6960989-6961083
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_25

Consensus_repeat	Method
CTCCGCCACCCGAACCCCCGAAAAGCGGCTGTG	CRISPRCasFinder

spacers of NC_017186_25

>25.1|6961022|29|NC_017186|CRISPRCasFinder
ACAACCGGGGCTTCGCCCCGAGCCGGGGG

CRISPR arrays and Neighbor proteins around NC_017186_25

CRISPR arrays

The CRISPR arrays of NC_017186_25

>merge|NC_017186|25|6960989-6961083|CRISPRCasFinder
CTCCGCCACCCGAACCCCCGAAAAGCGGCTGTGACAACCGGGGCTTCGCCCCGAGCCGGGGGCTCCGCCACCCGGACCCCCGAAAAGCGGCTGTG

>NC_017186|25|24|6960989-6961083|CRISPRCasFinder
CTCCGCCACCCGAACCCCCGAAAAGCGGCTGTG	ACAACCGGGGCTTCGCCCCGAGCCGGGGG
CTCCGCCACCCGGACCCCCGAAAAGCGGCTGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013228078.1|6968731_6969346_+|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl|CDD|179647
NC_017186.1|WP_013228068.1|6958827_6959469_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl|CDD|273139
NC_017186.1|WP_013228071.1|6961723_6962158_+|hypothetical-protein	unknown	unknown	gnl|CDD|370266
NC_017186.1|WP_013228074.1|6963293_6963800_-|RloB-domain-containing-protein	unknown	unknown	gnl|CDD|379341
NC_017186.1|WP_013228077.1|6967870_6968698_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NC_017186.1|WP_013228063.1|6953808_6955218_-|amidase	unknown	unknown	gnl|CDD|236177
NC_017186.1|WP_013228064.1|6955727_6956714_-|hypothetical-protein	unknown	unknown	gnl|CDD|234919
NC_017186.1|WP_013228069.1|6959465_6960902_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl|CDD|273453
NC_017186.1|WP_013228061.1|6952173_6952734_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NC_017186.1|WP_013228060.1|6950760_6951807_+|adenosine-deaminase	unknown	unknown	gnl|CDD|236480
NC_017186.1|WP_013228075.1|6963865_6965083_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|379114
NC_017186.1|WP_013228062.1|6952799_6953837_+|quinone-dependent-dihydroorotate-dehydrogenase	unknown	unknown	gnl|CDD|235388
NC_017186.1|WP_013228076.1|6965164_6967654_-|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|224588
NC_017186.1|WP_013228067.1|6958363_6958825_-|CinA-family-protein	unknown	unknown	gnl|CDD|334938
NC_017186.1|WP_014467438.1|6957805_6958264_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_017186.1|WP_013228079.1|6969384_6969927_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013228065.1|6956737_6957577_-|PspA/IM30-family-protein	unknown	unknown	gnl|CDD|224755
NC_017186.1|WP_013228072.1|6962208_6962820_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|376405
NC_017186.1|WP_013228073.1|6962812_6963124_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013228070.1|6961122_6961632_+|amino-acid-N-acetyltransferase	unknown	unknown	gnl|CDD|236132

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013228078.1|6968731_6969346_+|NAD(P)H:quinone-oxidoreductase	gnl|CDD|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	3.21245e-47
NC_017186.1|WP_013228068.1|6958827_6959469_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl|CDD|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	2.35224e-33
NC_017186.1|WP_013228071.1|6961723_6962158_+|hypothetical-protein	gnl|CDD|370266	pfam09056, Phospholip_A2_3, Prokaryotic phospholipase A2. The prokaryotic phospholipase A2 domain is predominantly found in bacterial and fungal phospholipases, as well as various hypothetical and putative proteins. It enables the liberation of fatty acids and lysophospholipid by hydrolysing the 2-ester bond of 1,2-diacyl-3-sn-phosphoglycerides. The domain adopts an alpha-helical secondary structure, consisting of five alpha-helices and two helical segments.	5.90058e-57
NC_017186.1|WP_013228074.1|6963293_6963800_-|RloB-domain-containing-protein	gnl|CDD|379341	pfam13707, RloB, RloB-like protein. This family includes the RloB protein that is found within a bacterial restriction modification operon. This family includes the AbiLii protein that is found as part of a plasmid encoded phage abortive infection mechanism. Deletion within abiLii abolished the phage resistance. The family includes some proteins annotated as CRISPR Csm2 proteins.	3.90487e-33
NC_017186.1|WP_013228077.1|6967870_6968698_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	6.08482e-32
NC_017186.1|WP_013228063.1|6953808_6955218_-|amidase	gnl|CDD|236177	PRK08186, PRK08186, allophanate hydrolase; Provisional.	3.09173e-84
NC_017186.1|WP_013228064.1|6955727_6956714_-|hypothetical-protein	gnl|CDD|234919	PRK01209, cobD, cobalamin biosynthesis protein.	0.00197828
NC_017186.1|WP_013228069.1|6959465_6960902_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl|CDD|273453	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO. Members of this protein are the methylthiotransferase RimO, which modifies a conserved Asp residue in ribosomal protein S12. This clade of radical SAM family proteins is closely related to the tRNA modification bifunctional enzyme MiaB (see TIGR01574), and it catalyzes the same two types of reactions: a radical-mechanism sulfur insertion, and a methylation of the inserted sulfur. This clade spans alpha and gamma proteobacteria, cyano bacteria, Deinococcus, Porphyromonas, Aquifex, Helicobacter, Campylobacter, Thermotoga, Chlamydia, Streptococcus coelicolor and Clostridium, but does not include most other gram positive bacteria, archaea or eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification].	5.33991e-127
NC_017186.1|WP_013228061.1|6952173_6952734_+|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.74192e-39
NC_017186.1|WP_013228060.1|6950760_6951807_+|adenosine-deaminase	gnl|CDD|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	3.35767e-126
NC_017186.1|WP_013228075.1|6963865_6965083_-|AAA-family-ATPase	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	2.90235e-34
NC_017186.1|WP_013228062.1|6952799_6953837_+|quinone-dependent-dihydroorotate-dehydrogenase	gnl|CDD|235388	PRK05286, PRK05286, quinone-dependent dihydroorotate dehydrogenase.	1.30045e-174
NC_017186.1|WP_013228076.1|6965164_6967654_-|DNA-translocase-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	1.08418e-163
NC_017186.1|WP_013228067.1|6958363_6958825_-|CinA-family-protein	gnl|CDD|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	6.66267e-50
NC_017186.1|WP_014467438.1|6957805_6958264_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	6.18809e-08
NC_017186.1|WP_013228065.1|6956737_6957577_-|PspA/IM30-family-protein	gnl|CDD|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	4.17185e-32
NC_017186.1|WP_013228072.1|6962208_6962820_+|nitroreductase-family-protein	gnl|CDD|376405	pfam00881, Nitroreductase, Nitroreductase family. The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.	2.1832e-23
NC_017186.1|WP_013228070.1|6961122_6961632_+|amino-acid-N-acetyltransferase	gnl|CDD|236132	PRK07922, PRK07922, amino-acid N-acetyltransferase.	1.83247e-100

Protein sequences

>NC_017186.1|WP_013228069.1|6959465_6960902_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MPSPATDPAAPRRVSLLTLGCARNEVDSEELAGRLAAGGWELAADPEDSDVVVVNTCGFVESAKKDSVDTLLAASDTGKKVVAVGCMAERYGHELADSLPEADAVLGFDHYADLSARLDDVVAGRKIASHTPGDRRKLLPISPVQRPAAAETVEVPGHAQHGWGPRVLRTRLDDAPVAALKIASGCDRRCSFCAIPSFRGSFVSRQPDEIVAEAMWLAEHGVKELFLVSENSTSYGKDFGRDGATALERLLPRLAEIDGIERVRVSYLQPAETRPQLVKAIATTPGVAEYFDLSFQHSSEQVLRRMRRFGSTDSFLALCEQIREYAPEAGIRTNVIVGFPGETEHDLAELERFLTGARLDAVGVFGYSDEDGTEAETFDGKLDPEEVGRRVTRISALVEELTTQRAEDRIGTFVDVLVELDDDGELTGRAAHQAPEVDGECIILDAPEKVQVGDFLRCEVVDSAGVDLIVRAVPDADR
>NC_017186.1|WP_013228068.1|6958827_6959469_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MSALPSDAADEGLARDAPAQLPEPTPVPTLNVANLLTLSRLVLVPLFVVALFVGDGHDETWRAIATGLFAIASATDQLDGWVARKYGLITDFGKIADPIADKALTGAALVGLSVLGELGWWVTIVIAVREIGVTLLRFWVIRHGVIPASRGGKAKTMAQIAAIVAYLLPLPAGADPVRWALMGLALVLTVVTGVDYLVRAVRLRAAGRRVTGS
>NC_017186.1|WP_013228067.1|6958363_6958825_-|CinA-family-protein
MDETALVAALAARGETVAAAESLTAGLVCATLARVPGASAVLRGGLVVYATELKAALAGVDPELLAEHGAVHPEVAAQLAEGARDRCGATWGLGLTGVAGPSAQDGVEPGTVHLGLAGPGTRTVRTLDLTGTRDLIRTESVLAAFALLGEHLA
>NC_017186.1|WP_014467438.1|6957805_6958264_-|helix-turn-helix-transcriptional-regulator
MTVLLREAIGDRLRHARTNQRRTLRDISRAARVSLGYLSEVERGQKEASSELLASICQALDLPLGELLHNVAADVSALDHVEVPPVDERIVEGTPREKRGAEASAAGIEGGRLMSELIGNDLADLRVSPAPRMNTTLRTTIGQPKLASTIAA
>NC_017186.1|WP_013228065.1|6956737_6957577_-|PspA/IM30-family-protein
MANPFVKFWKYMMAAFSSKIDEHADPKVQIQQAIEEAQRNHQALTQQAASVIGNQRQLEMKLNRQLGEVEKLQASTRQALVLADEARGKGDEQKATEFENAAESFATQLVTAEQSIEDLKTLHDQSLQAAAQAKKAVERNSQMLQQKLAERTKLLSQLEQAKMQEQVSASLNQMSQLAAPGNTPSLEEVRDKIEKRYTTALGSAELAQNSVQGRMMEVQASTTQMAGQSRLQQIRASMHGDSVAQVTDGGKTAPAASSQADIQREIQARVQAEQGKNPA
>NC_017186.1|WP_013228064.1|6955727_6956714_-|hypothetical-protein
MAQQGRRRDFSELSAKLEKHIEKLPDYAVRAQEQLQKVQKYFPPAEQAGGKPAPRRPNPLQRPPVRRPDMTASLSSMASQVPAFAEARAKWDRWNHPAAKLERRKRRTSKALTLWIILTILCAVVTVAAAVGWLSPTSAAMMPQAITAFAGAVIFGTFSVRSGLKLRELKRIPIPAAPAGPPPLPPARSAAREPMERLAECEASLTELLRQLSVPSSLGMPPVSEVSVADARQTATEAAAALRGLAARIQAIERGRDSAPAREKAALDAAVAKLREQLDDGLEGYRGLVAAAGHSVAAAGDGLVTSKQALTDATDRLAGLAMALRELS
>NC_017186.1|WP_013228063.1|6953808_6955218_-|amidase
MNTLPPDPDPVPDTPPTASQRVISAFERLTEAGRPELWTTLRAVEDVLVDAKAVDERVKAGEVLPLAGTVIAVQDLIDVAAQPSGHGVPETSAAVVTRLTAAGAVVLGKTGAAQISGAWDRTKAGGNGAAVAVALGVVDLALSTGGAVPAALNAVAAVKPTRGLLPAADNVSVYANGLVAAHRALTLMTGGDRHWPADVRLGAGEHPRVAYPTDLPLGEAASLALEAVVTRLIAAGAVLTPISVLEQGFDGFDALLVPTVPEHPGIAEALADPVGVGHRLASCTAFANLLDVASVTVPVLPGDRRPFGVTFLTRAFEDQIALDLATVCTDEPMTPYPEPGEDVIVFGAHLRGQPLNADLTALGARFTGPVRTTESYRMVLLDTEPPQPGVLDGDTGLDGERWRLSPAAFEQFATTLKPPFVLERVELADGTTPLAVRCDPAAEGPGLERYESWRGYVRFASTAGLRDPG
>NC_017186.1|WP_013228062.1|6952799_6953837_+|quinone-dependent-dihydroorotate-dehydrogenase
MFFDKIVRPALYRLSYHDPELVHERTIGVLARLGKAAPALGGALRVDDPVTVLGLRFPNRVGLAAGLDKNGRALPAWAALGFGFVEAGTVTRLAQPGNPKPRLFSLPASDAVINRMGFNNDGAEALAAKLARDGKPGVPLGVSIGKSKVTPLEDAVEDYRFSLRALHPYADYFAINVSSPNTPGLRQLQDRTALAELLGELRSTSLELAGGGSPTPVLVKVAPDLTDDALAELLEVALEHGVAGIIATNTTLARDGIAPAESGLAGQAGGLSGRPLTTRAAEVVRFVHDHTGGSLPIIGVGGIMGPDDAIRLVDAGASLVQLYTGFALHGPGLVRRVSRGLAARR
>NC_017186.1|WP_013228061.1|6952173_6952734_+|GNAT-family-N-acetyltransferase
MLRPDYPITTARLILRPFTPGDLDALNSFQSRADVARYLYWGPRSRAESAAALAKRVHSSTLTKEGQLLAVAVELAATGQLIGDLNLEWLSSEHRQGEIGFVFHPDHHGKGLAAEAATELLRLGFEDLGLHRIVGRCDGRNTASAALMERLGMRREAHLKENEIVKGEWADELIYAMLEDEWKDRD
>NC_017186.1|WP_013228060.1|6950760_6951807_+|adenosine-deaminase
MPAILTGQALRAFAHALPKVELHVHLVGSASLPTVLELARRRPAAGVPTDERELAEFFTFRDFAHFLTVYLAVTSLVRDRHDIHTLVTGLAADLAAHHCRYAEVTVTPYNHLLDGMSGDDLLAGLETGRARAAELGVELAWCFDIPGEKGVRAGRETLVFALRERPAGLVSFGLGGPELGVGRAQFEPFFTRAREAGLHSVPHAGETTGPATIWSALHDLGAERIGHGTSCAADPALLEHLAAHRIPLEVCPTSNVRTGQVADIAAHPVRRMLDHGLVVTLNTDDPPMFGATLTGEYVAVAETLGLTTAELVRLAENAVAASFLDEQRKAVLRTEITEMTLPRATDFA
>NC_017186.1|WP_013228070.1|6961122_6961632_+|amino-acid-N-acetyltransferase
MPSDSLRPTVRRARIADVRKIKALVDSDAGRVLLEKDLVTLYEAVQEFWVAEVGDEVVGAAALHVLWEDIAELRTVVVDKAVRGQGVGRLLVARLVDEARELGLKRLFVLTFETRFFTGHGFVEIDGTPVSHEVYEEMRRSHDTGVAEFLDLPYVKPNTLGNSRMLLEL
>NC_017186.1|WP_013228071.1|6961723_6962158_+|hypothetical-protein
MRTTLRNLGATVTVAVSVGAGALLGTGTAAAVDIPAVTDQYLFSTSLSGFETIRNQAPYSGQLDWSSDGCSWAPDNPFGWQFLPGCHRHDFGYRNYKKQGRFTEANRLRIDDNLYSDLKSVCGSNIACKGAAWTYYEAVRKFGG
>NC_017186.1|WP_013228072.1|6962208_6962820_+|nitroreductase-family-protein
MDIDHLLSTTRAVRRKLDLDRPVEPEVLEECLNLALQAPTPGNVQAWRWLVVRDQDAKNRLGAIFREVGEAYLAERASSAPSRALASGRHLIDVIERVPVFVIPVVAGRPAGDNGVDAAFYGGIFPAVWSFQLALRSRGLGSTLTTYHLAREAEAAEILGIPDGHTQVGLLPVAYTTVPDFKPAPRTPLSEVAFLDHWGTPLS
>NC_017186.1|WP_013228073.1|6962812_6963124_-|hypothetical-protein
MSAPAGHDVTLRLGQEAAVQGKDLTVRYTRVVADSRCRPGMQCIWQGEATLAFLLKEPGRGESTTAELHSGPRTGPQATSFAASRIELVSVGEDAGEATVRIS
>NC_017186.1|WP_013228074.1|6963293_6963800_-|RloB-domain-containing-protein
MCGAEATEPAYFQGLKQARRNPAVTIKLKAKPADPDTVVRHAAGLRDNAADTYDEVWCVVDVDEFDVAKAVVTARRVRVNLAISNPCFEYWLLLHFEACTAPLTCYSDVARRLRRHVPEYDKTALRFADYASGVDAAVERSLGRGHVLTTEHEHNPATGVWALVKKVL
>NC_017186.1|WP_013228075.1|6963865_6965083_-|AAA-family-ATPase
MLRSFRLGNHRSFRDEQELLLMPAMPGDERPVVPVTAIYGANASGKSNLFKGITLARWAVLNRHLPDATGRHDIVALQDPFRLDPQSPDRPSTFVFELIAEGIQYTYGFLLQETEILEEWLYAYPEKRKRLIFERNRSAIKFGSTVADLKAKFEVLEEWIRSTVLFLSVCDRLELGPLIPVYRWFEAGVLASGFDGPSPDPEYVQWVVGDYLLRNPEARQRMIALLKVADVGIVDVVVADRKDRTRRRAAQSDLELKLLHGASSEPFDFGDESSGTRNWIGFLPMVLRALDGGLVLFVDEIDASLHPLLTAKLVGLFQDAEVNTKGAQLIFTTHDTSLLGTMLGEQVLERDQIWFVDRGAEGASHLYPLTDFKPRKDQNTERRYLAGSYGAVPVLGDFTAAVGRG
>NC_017186.1|WP_013228076.1|6965164_6967654_-|DNA-translocase-FtsK
MAGSATRKRSTGSGAKGAAARKPRTPAKPRTSSARKPPPRSRRKTPGLFGKGVRGTWNLLAKGLGTLARTVGRTRELEPEHRRDGLALGLIGLGIVAAVGVWWRAAGPIGLGVEIATRTVLGAGAVTLPLVLIVVAVALMRSEPHPETRPRMVVGTIMVVLSVLGMLHIFTALPGTNDGRMYAGGIVGAFSGGLLTMGVTTWVAVPLLILALFFGVLVFTGTPVREIPHRLRHWGLDEEELAEAEAQRSGFATDEDTVTEADPKSARLRKPSRRRQAAEAAPEQLDIDAMLAEAPTPIRPPKPKPAPEVVEKKPKKTPEPPLAVTRTVEGDYQLPPPDLLKLGDAPKSRSKANDAMIEAITGVLEQFNVDAQVTGFTRGPTVTRYEVELGPGVKVEKITALTKNIAYAVATDNVRLLAPIPGKSAVGIEVPNSDREMVRLGDVLRAPTTVKDNHPMVIGLGKDIEGHFVTANLTKMPHLLVAGSTGSGKSSFVNSMLVSLLARSTPDECRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQVNKVRHIDDYNKKVRSGEITAPPGSEREYRPYPYIMAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGAEKLIGMGDALYLPMGAGKPVRIQGAFVGDEEISAVVNYAKEQAQPDYQDGVTAQKAGEKKEIDPDIGDDLDVLLQAAELIVTSQFGSTSMLQRKLRVGFAKAGRLMDLLESRGVVGPSEGSKARDVLIKPEELESVLFMIRGGGPVDADASDDDE
>NC_017186.1|WP_013228077.1|6967870_6968698_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MLCPMLALRTDEPPRRAPAIWRTMLNIDRGLVNLVGRLTVSGRVPAQLRGKPLLMAANHIGVFDAFVLMAACKRIGINPRFMLAGGILDAPVIGPALRVSGHLRVDRKHAGTAVGQFAEAVEAMKTTREPIVVYPEGRISHDPGLWPERGKTGAARLALAAGVPVIPISQWGAHEAVYWGTETVNGPADLVPLARSGLSAPLRRPKFRVHFGDPVDLSDIDTQRPGAGVRAHAKIMQAITDGLVPLRRDELDRPRFHDPTRPTDTVSPWKPPSVL
>NC_017186.1|WP_013228078.1|6968731_6969346_+|NAD(P)H:quinone-oxidoreductase
MSTRILVVYYSSTGNTAALAESLATGAREAGADVRVRTVPETVPAEAIAQNPRWRAWIDAGPHHEFATLGDLEWADGLAVGSPTRFGGPAAQLKSYLDSTGGLWAQGKLADKVATSFTTASTAHGGLESTLLAINNVFYHWGAIVVPLGYTDPHLKESGNPYGGSFVSRKSAAPDDVALDALRLQGRRLATITTHVATGLKRAE
>NC_017186.1|WP_013228079.1|6969384_6969927_-|hypothetical-protein
MGVAAGFVLLSPVVASAAEAPTGNPTSMKVEVDDADNVTIEGTCVNSAVQAEAGYRVPGGHRPILHGDLIMQGKTGSVTYKHVPPGKYEAYIYCYEGGPGDHRGPVRTFTVGKSAQSAQPAKPTQTAPQVGVKPQGAPQTGGGPADDESTATPLLVGGAIALVGATGAGALVLRRRAARR

Crispr_ID: NC_017186_26

• CRISPR_ID: NC_017186_26
• CRISPR_location: 8279767-8280303
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of NC_017186_26

Consensus_repeat	Method
GCTCGGCTCGGCNCGGCCCGGCNCGGC	CRT

spacers of NC_017186_26

>26.1|8279794|62|NC_017186|CRT
GCTGGTCTGGGCTGCGCTCGGCTGCACTGCGCCAGGCTGAGCTTGCCCGGCGCGGTGGGGAA
>26.2|8279883|40|NC_017186|CRT
GCCGGGTTGGGTTGGGCTCCGCTCGGCCCAGCTCGCCTGG
>26.3|8279950|34|NC_017186|CRT
TGGGCTGGACTGGGCTCGGCCCGGCTCGCCCTGG
>26.4|8280011|19|NC_017186|CRT
CCGGCTCGCCCTGGGCTGG
>26.5|8280057|24|NC_017186|CRT
TCGGCCCGCCCTGGGCTGGGCTCG
>26.6|8280108|34|NC_017186|CRT
CTGGGTTCGGCTCGGCTCGGCTCGGCTCGGCTCG
>26.7|8280169|18|NC_017186|CRT
CCAGCTCGGCCCAGCTCG
>26.8|8280214|18|NC_017186|CRT
TCGGCTCGGCTCGGCTCG
>26.9|8280259|18|NC_017186|CRT
TCGGCTCGGCTCGGCTCG

CRISPR arrays and Neighbor proteins around NC_017186_26

CRISPR arrays

The CRISPR arrays of NC_017186_26

>merge|NC_017186|26|8279767-8280303|CRT
TCGGCTGCAGCGGCGGCCCGGGCCGCCGCTGGTCTGGGCTGCGCTCGGCTGCACTGCGCCAGGCTGAGCTTGCCCGGCGCGGTGGGGAACCCCGCTCGGCAGCGGCCCGGCCCGCCGCCGGGTTGGGTTGGGCTCCGCTCGGCCCAGCTCGCCTGGGCTGGGCTCGGCTCGGCCCGGCTCGCCTGGGCTGGACTGGGCTCGGCCCGGCTCGCCCTGGGCTGGACTGGGCTCGGCCCGGCTCGGCCCGGCTCGCCCTGGGCTGGGCTCGGCTCGGCCCGGCCCGGCCCGGCTCGGCCCGCCCTGGGCTGGGCTCGGCTCGGCTCGGCCCGGCCCGCCCTGGGCTGGGTTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCCCGGCCCGGCCCGGCCCAGCTCGGCCCAGCTCGGCCCGGCTCGGCCCGGCTCGGCCCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGCTCGGC

>NC_017186|26|6|8279767-8280303|CRT
TCGGCTGCAGCGGCGGCCCGGGCCGCC	GCTGGTCTGGGCTGCGCTCGGCTGCACTGCGCCAGGCTGAGCTTGCCCGGCGCGGTGGGGAA
CCCCGCTCGGCAGCGGCCCGGCCCGCC	GCCGGGTTGGGTTGGGCTCCGCTCGGCCCAGCTCGCCTGG
GCTGGGCTCGGCTCGGCCCGGCTCGCC	TGGGCTGGACTGGGCTCGGCCCGGCTCGCCCTGG
GCTGGACTGGGCTCGGCCCGGCTCGGC	CCGGCTCGCCCTGGGCTGG
GCTCGGCTCGGCCCGGCCCGGCCCGGC	TCGGCCCGCCCTGGGCTGGGCTCG
GCTCGGCTCGGCCCGGCCCGCCCTGGG	CTGGGTTCGGCTCGGCTCGGCTCGGCTCGGCTCG
GCTCGGCTCGGCCCGGCCCGGCCCGGC	CCAGCTCGGCCCAGCTCG
GCCCGGCTCGGCCCGGCTCGGCCCGGC	TCGGCTCGGCTCGGCTCG
GCTCGGCTCGGCTCGGCTCGGCTCGGC	TCGGCTCGGCTCGGCTCG
GCTCGGCTCGGCTCGGCTCGGCTCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013229257.1|8287130_8287544_+|SsgA-family-sporulation/cell-division-regulator	unknown	unknown	gnl|CDD|377399
NC_017186.1|WP_013229249.1|8278581_8279511_+|lipase	unknown	unknown	gnl|CDD|226651
NC_017186.1|WP_013229245.1|8275066_8276122_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380488
NC_017186.1|WP_013229240.1|8268485_8270240_-|beta-galactosidase	unknown	unknown	gnl|CDD|366567
NC_017186.1|WP_013229253.1|8283238_8283913_-|fasciclin-domain-containing-protein	unknown	unknown	gnl|CDD|367095
NC_017186.1|WP_013229246.1|8276763_8276949_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013229255.1|8285522_8286203_-|anti-sigma-factor	unknown	unknown	gnl|CDD|378389
NC_017186.1|WP_013229243.1|8273163_8274027_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NC_017186.1|WP_013229251.1|8281533_8282193_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|172294
NC_017186.1|WP_013229259.1|8288913_8290605_-|dihydroxy-acid-dehydratase	unknown	unknown	gnl|CDD|234861
NC_017186.1|WP_013229252.1|8282214_8283237_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274928
NC_017186.1|WP_013229241.1|8270232_8271777_-|alpha-N-arabinofuranosidase	unknown	unknown	gnl|CDD|226064
NC_017186.1|WP_014467637.1|8277784_8278384_+|hypothetical-protein	unknown	unknown	gnl|CDD|376024
NC_017186.1|WP_176742209.1|8286199_8286772_-|ECF-RNA-polymerase-sigma-factor-SigK	unknown	unknown	gnl|CDD|182015
NC_017186.1|WP_049878184.1|8271773_8273114_-|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270303
NC_017186.1|WP_176742208.1|8284006_8285530_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239028
NC_017186.1|WP_176742128.1|8276923_8277562_-|DsbA-family-protein	unknown	unknown	gnl|CDD|239322
NC_017186.1|WP_013229258.1|8287559_8288924_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341228
NC_017186.1|WP_013229250.1|8280453_8281434_-|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176228
NC_017186.1|WP_014467636.1|8274028_8274955_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013229255.1|8285522_8286203_-|anti-sigma-factor	gnl|CDD|378389	pfam10099, RskA, Anti-sigma-K factor rskA. This domain, formerly known as DUF2337, is the anti-sigma-K factor, RskA. In Mycobacterium tuberculosis the protein positively regulates expression of the antigenic proteins MPB70 and MPB83.	1.41482e-22
NC_017186.1|WP_013229257.1|8287130_8287544_+|SsgA-family-sporulation/cell-division-regulator	gnl|CDD|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	4.18407e-36
NC_017186.1|WP_013229249.1|8278581_8279511_+|lipase	gnl|CDD|226651	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only].	2.72064e-08
NC_017186.1|WP_013229245.1|8275066_8276122_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380488	cd01574, PBP1_LacI, ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of LacI is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	3.07325e-109
NC_017186.1|WP_013229240.1|8268485_8270240_-|beta-galactosidase	gnl|CDD|366567	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.	9.16508e-146
NC_017186.1|WP_013229253.1|8283238_8283913_-|fasciclin-domain-containing-protein	gnl|CDD|367095	pfam02469, Fasciclin, Fasciclin domain. This extracellular domain is found repeated four times in grasshopper fasciclin I as well as in proteins from mammals, sea urchins, plants, yeast and bacteria.	2.97926e-36
NC_017186.1|WP_014467636.1|8274028_8274955_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	3.79689e-68
NC_017186.1|WP_013229241.1|8270232_8271777_-|alpha-N-arabinofuranosidase	gnl|CDD|226064	COG3534, AbfA, Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism].	0
NC_017186.1|WP_013229243.1|8273163_8274027_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.96095e-64
NC_017186.1|WP_013229258.1|8287559_8288924_+|AMP-binding-protein	gnl|CDD|341228	cd04433, AFD_class_I, Adenylate forming domain, Class I, also known as the ANL superfamily. This family is known as the ANL (acyl-CoA synthetases, the NRPS adenylation domains, and the Luciferase enzymes) superfamily. It includes acyl- and aryl-CoA ligases, as well as the adenylation domain of nonribosomal peptide synthetases and firefly luciferases.The adenylate-forming enzymes catalyze an ATP-dependent two-step reaction to first activate a carboxylate substrate as an adenylate and then transfer the carboxylate to the pantetheine group of either coenzyme A or an acyl-carrier protein. The active site of the domain is located at the interface of a large N-terminal subdomain and a smaller C-terminal subdomain.	6.87303e-93
NC_017186.1|WP_013229259.1|8288913_8290605_-|dihydroxy-acid-dehydratase	gnl|CDD|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NC_017186.1|WP_013229252.1|8282214_8283237_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274928	TIGR04027, Luciferase-like_monooxygenase, putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family. This protein family consists of luciferase-like monooxygenases (LLM), and include KPN_01858 from Klebsiella pneumoniae as a representative member. Most are from species that lack F420 biosynthesis, so the family is likely to bind FMN as its cofactor. This family is closely associated with a binding protein-dependent ABC transporter, suggesting a role in catabolism. [Unknown function, Enzymes of unknown specificity].	5.39189e-30
NC_017186.1|WP_013229251.1|8281533_8282193_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|172294	PRK13756, PRK13756, TetR family transcriptional regulator.	2.79005e-13
NC_017186.1|WP_014467637.1|8277784_8278384_+|hypothetical-protein	gnl|CDD|376024	pfam18598, TetR_C_36, Tetracyclin repressor-like, C-terminal domain. This is a C-terminal TetR regulatory domain found in QsdR proteins (quorum-sensing degradation regulation).	2.16616e-30
NC_017186.1|WP_176742209.1|8286199_8286772_-|ECF-RNA-polymerase-sigma-factor-SigK	gnl|CDD|182015	PRK09646, PRK09646, ECF RNA polymerase sigma factor SigK.	3.79067e-85
NC_017186.1|WP_049878184.1|8271773_8273114_-|sugar-ABC-transporter-substrate-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.04056e-54
NC_017186.1|WP_176742128.1|8276923_8277562_-|DsbA-family-protein	gnl|CDD|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	6.69441e-87
NC_017186.1|WP_013229250.1|8280453_8281434_-|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176228	cd08267, MDR1, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	4.097e-116
NC_017186.1|WP_176742208.1|8284006_8285530_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|239028	cd02110, SO_family_Moco_dimer, Subgroup of sulfite oxidase (SO) family molybdopterin binding domains that contains conserved dimerization domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). .	2.26065e-71

Protein sequences

>NC_017186.1|WP_013229249.1|8278581_8279511_+|lipase
MSALTSQPTSSGSSEKIPRLRGWRAKAAGVVLAALALTTGVAAPAPAAANPYERGPDPTTASIEATSGSFATSTVTVSRLAVSGFGGGTIYYPTTTTAGTFGALSIAPGFTATQSSIAWLGPRLASQGFVVFTIDTLTTSDQPDSRGRQLLASLDYLTQQSSVRSRIDSTRLGVVGHSMGGGGTLEAARSRPTLQAAVPLTAWDLTKNWSTLQVPTLVVGAQSDTVAPVASHSIPFYTSLPSTLDRAYLELRGASHFAPNSPNTTIAKYTLSWLKRFIDNDTRYEQFLCPIPSTSLSISDYRGNCPHNG
>NC_017186.1|WP_014467637.1|8277784_8278384_+|hypothetical-protein
MTVSTDDIVRHAARLLMAGTRLDLGRMAAELGISRTTFFRRVGNRDDLMGAGLRLLSDRTWQRALDGWRAGHGEAVRTPEGRLRCLWVMEEYRREVAGSDGMRKLIEAESAVALRVLTDPRGAVQPGLVDAHVELFRADADAAGLAPLVGLPDLAFAVVRLGESFLYSDVLAARSVDLTVATTLVDTLVRGALEPVRVH
>NC_017186.1|WP_176742128.1|8276923_8277562_-|DsbA-family-protein
MRVDIWSDLVCPWCYLGKRRFERAVAEAGVDVEVVHHSFQLDPSFPRGTSKPTREVLAEKYGRTLEEADAMEAQMEERAAADGLEYHLDGVHMGNTVDGHRLVHLAQERGVADAVIDRFYRAHFTERRSLFDHESLVELAAEAGLDADEARAVLESDAYEAEVASDGEQARALGASGVPFFVIDERYGVSGAQSPEVFAQVLRRVSDGAAAG
>NC_017186.1|WP_013229246.1|8276763_8276949_+|hypothetical-protein
MLAILAAVLFGLALLMELAGFGLGPVITTGTLTTAGLLCVALHLAGVATDRSRFTRRRRRR
>NC_017186.1|WP_013229245.1|8275066_8276122_+|LacI-family-DNA-binding-transcriptional-regulator
MTVPRQTATSSASGHATRRRGPSMADVAREAGVSGQTVSRVANGKTNVDDATRERVLAAMRRVGYRPNSAARALRNGQFRSIGVIISALPTFGNSRTLDAIAAAVVPEGFSIILMPVTRPTQGEVTGAFSTLNEQAVDGVIILIEQHQLDQSEIELPHGLPVVVIDSSARYDYPVVDNDQADGAARATSHLLSLGHSTVWHIAGPPQSYSAERRRKSWQATLERAGRPVPPVVVGDWSPESGYQAGLRLAADPTVTAVFAANDQMALGLLRALHETGRGVPSEVSVVGFDDMEESAHFWPPLTTIRQSFEAVGRHAVEALLTEIETGAEAGEPVLLPTELVIRSSTAPPPA
>NC_017186.1|WP_014467636.1|8274028_8274955_-|sugar-ABC-transporter-permease
MTSTAAPPAPVPARRAPAARRPRRKWRGWLFVAPFMLVFALTFVAPVVYAFVLSLFRDQAFFGGTVFVGADNYVQVFGDPKFWEAFRRVLVFLAVQVPIMLVLALIAALAIDSARLHGAGFFRIVIFLPYAVPAVVAALMWGFIYGDHFGLAADLNHLLGTAVKPLSPSWLLTSIGNIVTWEFVGYNMLIFYSALKVIPKELFEAAAIDGAGTFRTIVSVKLPAIRGAIVVATIFSIIGSFQLFNEPNIMRNLVPNTIGTFYTPNMYAYNLSFNGQQYNYSATVAIVMGVITAVIAYVVQLRGSRKEM
>NC_017186.1|WP_013229243.1|8273163_8274027_-|carbohydrate-ABC-transporter-permease
MATFSVTQPRKSRVLTGFMALYLLYTLVPLVWLVINASKTQPALFSTSGLSFGGTFALFDNIGQTFTYNGGIFFRWLGNTLLYVVVGAGGATILATAAGYGLAKYRFPGRRAVFAVVLGAVAVPPTALAVPTFLMFSKLGLTNTPLAVIIPSLISPFGLYLIWVYAADAIPDELLEAARIDGAGEIRIFLTVTLRQLVPGIITVTLFTMVQTWNNYFLPLIMLSEPKWYPLTVGLNQWSAQANGAGAQPIFNLVLTGSLLTIIPLVVAFLLMQRFWQSGLSAGSVKQ
>NC_017186.1|WP_049878184.1|8271773_8273114_-|sugar-ABC-transporter-substrate-binding-protein
MSRFRTRAKAAAAVALAAALAVGCSSGGSSSAPAAATGTQDSVDAALKAGGEITYWSWTPSAKDQVAAFEKEYPNVKVNYVNAGTNKDEYTKLQNAIKAGSGAPDVAQIEYYALPQFALTDSLADLNQFGFGSFEKDYSASTWAQVKNGNGVYGLPQDSGPMALFYNKEVFDKNGIAVPKTWAEYIEAAKKLHTADPTKYMTSDTGDPGAVLSMIWQAGGRPFAVDGKNVKVNFGDAGTKKWTALWDQMIQGKLLAPVKEWSDDWFRALGDGTVSSLVTGAWMPGNFISSVPGASGKWAVAPMPTYDGKPVTAENGGSAQSVVKQSKNAPLAAAFVRWLNHGGGVQPFIKSGGFPSTTADLTSPAFVDQEVPYFGGQKINQVLTQASKDVAPGWSYLPYQTYANSVFSDTAGKAYLNGTGLDAGLAAWQQAIVDYGNQQGFTVSAG
>NC_017186.1|WP_013229241.1|8270232_8271777_-|alpha-N-arabinofuranosidase
MTVHIEGDAGQVIGPVPRRLFGSFVEHMGRSVYTGLYEPGHSTSDDRGFRGDVLELVRELGPTVLRYPGGNFVSGYRWEDGVGPAETRPVRLDPAWHSVEPNRFGLHEFVAWAEAAGAEVMYAVNLGTRGIQEAADVLEYCNHAGGTELSERRRANGADRPFGFKLWCLGNEMDGPWQIGHKTADEYGRLAAETARLMRMIDPGVELVVAGSSHADMPTFGSWERTVLRHTAELVDHISLHAYYQELHGDTDSYLASAAALDQYIATTAGVIDETLDELGLDKKIGISVDEWNVWDLRRWNEVDQAKLAAGGWREHPRIIEDTYTVTDAVVVGSLLSSLLRNVDRVTMANQAQLVNVIAPIRSEPGGPAWRQTTFHPFRQVAALAGGASLRLSVEGARLRTAQHGEVDLVDAAATVEDSGRGAVFLTNRATASATEVRIRLRGARFGVYAAETLTTPDGETRHTVNTADAQPVRPVPLPGTVTTSDPGGTTITVTLPPLSWTVLQLTPQAAPNA
>NC_017186.1|WP_013229240.1|8268485_8270240_-|beta-galactosidase
MPEFAIGEHDFLLDGRPFRILSGALHYFRVHPDLWADRIDKARRMGLNTIETYVAWNAHAPEPGTFDLSGGLDLDRFLRLVADAGMYAIVRPGPYICAEWDNGGLPAWLFRDPSVGVRRYEPKYLDAVREYLTKVYEVVVPHQIDRGGPVLLVQVENEYGAFGDDKRYLKALAEHTREAGVTVPLTTVDQPTPEMLEAGSLDGLHRTASFGSGAEARLAILRAHQPTGPLMCSEFWNGWFDHWGAHHHTTSAADSAAELDALLAAGASVNLYMFHGGTNFGLTNGANDKGVYQPLITSYDYDAPLDEAGDPTPKYHAFRDVIARYHKVPDTVPPPARPAPTPSGVLGDPVRLLDAPERWGTWEFHEELPAFDDLTPMPQLALLRCAVEGDRSGVLTFGEVRDRATVFFDGDLVGTLSRDHHERAIPLPRGRGELLVLVEDQGRVDYGPRIGEAKGIIGGASLQGEPLAGWDVLPLDLAALPALRPPAPESVTGAVAGPVVLRTEIDLDEPADLFLDTGEWGKGVAWLNGFALGRYWRRGPQRTLYVPRPVVRAGANELVVLELGTMLDPAARFVPRPLLGHTEA
>NC_017186.1|WP_013229250.1|8280453_8281434_-|NAD(P)-dependent-alcohol-dehydrogenase
MKALVQHVYGAASSLVLEDVPEPVPGEGEVLVRVRATSVNPYDWHFMRGEPYVARLMTGGFGLRRPPVGVLGCDLAGRVETAGTRFAPGDDVYALLPRGAHAEYVCVREDLLAPMPANLTHEQAAAMPMAAVTALVALRGVEAGQRVLVNGASGGVGTFAVQLAKALGAQVDAVCGAANAEMVRSLGAGHVFDYRAEDFTRSGRGYDVVLDIAGSRSVFACRRVLARDGTFVAVGGPAGRWVQPAGHVFSALASGPLARRRVVLADAVACADKAAALGELAGMVERGAVTPVIDRSYPFDDLREAFAYQEAGHARGKVVVTIGAPA
>NC_017186.1|WP_013229251.1|8281533_8282193_+|TetR/AcrR-family-transcriptional-regulator
MTTDARMPLSRERVLRAAVGLADEHGLRALTMRRLAEELGAEAMSLYYHVAKKEDVLDGIVDVVAGEINEAVGRIEAGPDWKTAVRERILAARQVFLRHRWAPGLFETRSSTSTEVLRYFDALVGLMRNGGFSYDLVHHALHALGSRALGFSQELFDPSAGESADVPVDLVWQLPNLVGMLSEIAHDDPHSTLGWCDDQAEFEFGLDVILDGLDRLRTQ
>NC_017186.1|WP_013229252.1|8282214_8283237_+|LLM-class-flavin-dependent-oxidoreductase
MRGGRIGTVSRPLRKLGFLTIGLFDAADPRRGHESTLEIIELGERLGFDSAWVRHRHLQYGISSPVAVLAAASQRTSRIELGTAVIPLGWENPLRLAEDLATVDLLSGGRLNPGLSVGPPMRWDDVKDALYPDTADAEDFSYDRVERLLGFVRGEPATGFSGTQGFEVFSDRVQPQSPGLGDRLWYGGASLRSAQWAGEHRMNFLTSSVVKAEGESTDFAEIQLSHIRAFREHHPAGRISQGLVVIPTDSATPHQRAKYEAYAEKRLPRTAEPQGPARTLFSPDFVGTSAEIAERLHAHKAFREIDEVAFALPFTFEHEDYVQILTDIAERLGPALGRNS
>NC_017186.1|WP_013229253.1|8283238_8283913_-|fasciclin-domain-containing-protein
MTKLRVAGIGVAAVAALSLTACSGSDTASSGSSSSSMAPSSSVPAPSSSMASGAANGVTTNADVFGPACSQLPQGSSPGSLDSMGPQPVASAASTNPLLTKLVAAVKATNLVDTLNSQEAITVFAPADPAFAALGDAKFNELAGKPAELAPILQYHVVGKRYDAKGLATAGSVDTLNTAGGPVKIEGSGDNMTVNGAKILCGNIPTKNATVFVIDKVLTPGTNK
>NC_017186.1|WP_176742208.1|8284006_8285530_-|molybdopterin-dependent-oxidoreductase
MSSGRSLRRWRAALLGVLALVAALAAGHLVAGFVGVNASPYLAVGNGAIDLTPVWLKDFAVRTFGTYDKLVLLSGMAVAMVAVAAVAGLLSRRTPVPGLVVITGVGLVGLVAVYARPDLDVVALLAPLASLVAGVATFAFLHRLARREAVSDASRRTVLLAGAGVVVGAGVAGLGGQLLAGSRDATSSREAVGRLVPARTAPMIPADADFAKLGTPPFLTSNTRFYRVDTALSVPQVRTEDWSLRLHGMVDREIRYRYADIRNRPLVERTITMTCVSNEVGGTYVSTANFVGVDLADLLDEAGVRPGAEQLFSSSVDGWTSGSPVAAALDRTRGAMLAIGMNGEPLPIEHGFPARLVIPGLYGYVSATKWVTDLEVTTWGARQAYWLKRGWGREAPIKTESRIDTPKGFETVSSGKVRVAGIAWAQHTGITKVELRMDNGPWREAMLSHEVNVRTWRMWWLEFDVAPGGHQVVCRATDKSGYTQTEMRAGTVPDGATGWHSIAFTAR
>NC_017186.1|WP_013229255.1|8285522_8286203_-|anti-sigma-factor
MTAELHMLTGAYALDAVSDVDRAEFERHLGECAACQEEVAELRATGARLAVAAAVATPPELKPVVLAEVARTRQLPPKLPVVRRLSRAKTWQLRISLFGAAAAAVVAVVLGVARTPAPVDSVLGAPDASAIQGAGQGHATLVVSRSRNQAVLLASDLPALDAGHVYQVWLIGSRGARSAGLMTSEASQRMLVAELPSDVDRIGITVEPAGGSAGPTTPAVTRISLV
>NC_017186.1|WP_176742209.1|8286199_8286772_-|ECF-RNA-polymerase-sigma-factor-SigK
MQPDEAQALAPSAEELLRRVAAGDETAFASLYDLVAGPVLGLATRVLRSHAQAEEVAQEVLVEVWRKATRYEPERGSALSWVLTIAHRRAVDRVRSHQAGVDREERAGLMDVRRPFDEVTESTLAGLEQQRVRQCLAALTELQRESIVLAYYNGYTYPEVAEVLKVAPGTVKTRIRDGLIRLRDCLGVDR
>NC_017186.1|WP_013229257.1|8287130_8287544_+|SsgA-family-sporulation/cell-division-regulator
MADPNTVITARIDFALRTFGAGPRPVPAELEYDTLDPYAVAVVLHAGPSAVRWLFGRDLLADGLLARCGDGDVRIGPAGDPALVLVELSSPDGAAVLEAPAKEIAAFLDRTYDVIPAGSESDWFDFDEELAKLSYQD
>NC_017186.1|WP_013229258.1|8287559_8288924_+|AMP-binding-protein
MSFFLTKVLAALDDGGDHVLFHCGGDVTTYRQARDRLRRLHGGLGDVETLAVDLRNRPETVLVQLAALLRGATVLMVPASAPARDRLAAVNGATVVTDRPHDWPAGDVRTLDDLDDEPGPLRPPETVRLLFPTGGTTGTPKLIRHSGIYDGMAYLFTPSPDGPGRTLLVAPMTHMTGNATVLGALLRLDTVVVHDGFDAEAVLDAIQAHRIDTLSLTPPRLAALLDHPARESTDLSSVRSLSLGAAPLPPHRLTQALDVFGPVVGQGYGLTEAPMIASISAAELIARPELRSSVGRIVPGMEARLTDGEVEVRGLSMMDGYLGGPEIGAGWLRTGDLGRFDDEGYLYLLDRVDDVVVVGEHGTKVATTVVEHALAAHPAVRSAAVFGVPGEDGQLLHAVVVASAEVTSEEVRAHARDAFGQEHYVPASVDFVAALPLTSVGKVDKRALRAAFSS
>NC_017186.1|WP_013229259.1|8288913_8290605_-|dihydroxy-acid-dehydratase
MTIDPKPRSRTVTDGIEAAPARGMLRAVGMGDGDWQKPIIGVASSWNEITPCNLSLDRLAQAAKEGVHAGGGYPLQFGTISVSDGISMGHDGMHFSLVSREVIADSVETVMQAERLDGSILLAGCDKSLPGMLMAAARLDLASVFLYAGTIAPGWVKLTDGTEKDVTLIDAFEAVGACRAGRLGTADLDRIERAICPGEGACGGMYTANTMASAAEAMGMSMPGSAAPPSADRRRDHYAHLSGEAVVGLLEKGITARDILTREAFENAITVVMALGGSTNAVLHLLAIAHEAKVSLTLDDFNTVGDRVPHLGDLKPFGKYVMNDIDRHGGIPVLMKALLDEGLIHGDALTVTGRTVAENLAALDPDPIDGEVLRTLDNPLHPTGGITILRGSLAPEGAVVKSAGFDTANFEGPARVFEREQEAMAALNEGRISAGDVVVIRYEGPKGGPGMREMLAITAAIKGAGLGKDVLLLTDGRFSGGTTGLCIGHVAPEAVDGGPIAFVRTGDRIAVDIKARSIDLLVDAAELASRRAGWEPLPTKFPEGVLGKYVKLVKSSSDGAVTS

Crispr_ID: NC_017186_27

• CRISPR_ID: NC_017186_27
• CRISPR_location: 10142210-10142316
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017186_27

Consensus_repeat	Method
GCCCCCGCCCGGCGGCCGCCGTCC	CRISPRCasFinder

spacers of NC_017186_27

>27.1|10142234|59|NC_017186|CRISPRCasFinder
CCGCCCGGCGGCCGCCGTCCCGGTCAGTCGCCCGGCTCACCGCCGCAGGGCTTCCGGCA

CRISPR arrays and Neighbor proteins around NC_017186_27

CRISPR arrays

The CRISPR arrays of NC_017186_27

>merge|NC_017186|27|10142210-10142316|CRISPRCasFinder
GCGGCCGGCCGGCGCCAGCCGCCCCCGCCCGGCGGCCGCCGTCCCGGTCAGTCGCCCGGCTCACCGCCGCAGGGCTTCCGGCAGCCCCCGCCCGGCGGCCGCCGTCC

>NC_017186|27|25|10142210-10142316|CRISPRCasFinder
GCGGCCGGCCGGCGCCAGCCGCCC	CCGCCCGGCGGCCGCCGTCCCGGTCAGTCGCCCGGCTCACCGCCGCAGGGCTTCCGGCA
GCCCCCGCCCGGCGGCCGCCGTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017186.1|WP_013230990.1|10139570_10140659_-|inositol-3-phosphate-synthase	unknown	unknown	gnl|CDD|132491
NC_017186.1|WP_176742059.1|10154809_10155136_+|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|179034
NC_017186.1|WP_013230992.1|10141521_10141917_+|DUF5318-domain-containing-protein	unknown	unknown	gnl|CDD|379953
NC_017186.1|WP_013230997.1|10149423_10150974_+|DUF2029-domain-containing-protein	unknown	unknown	gnl|CDD|227937
NC_017186.1|WP_013230989.1|10138948_10139467_-|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NC_017186.1|WP_013231003.1|10155153_10155669_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|236092
NC_017186.1|WP_013230986.1|10137097_10137556_-|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NC_017186.1|WP_013230985.1|10135890_10137108_-|MFS-transporter	unknown	unknown	gnl|CDD|341027
NC_017186.1|WP_013231001.1|10153790_10154693_+|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013230995.1|10147214_10148261_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|183212
NC_017186.1|WP_013230991.1|10140731_10141277_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NC_017186.1|WP_013230988.1|10138253_10138952_-|hypothetical-protein	unknown	unknown	unknown
NC_017186.1|WP_013230983.1|10131973_10133593_-|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl|CDD|375050
NC_017186.1|WP_013230987.1|10137622_10138261_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NC_017186.1|WP_176742060.1|10152799_10153705_+|hypothetical-protein	unknown	unknown	gnl|CDD|236362
NC_017186.1|WP_013230984.1|10133715_10135782_-|PhoX-family-protein	unknown	unknown	gnl|CDD|253386
NC_017186.1|WP_013230994.1|10144784_10147139_+|penicillin-binding-protein	unknown	unknown	gnl|CDD|223815
NC_017186.1|WP_013230996.1|10148316_10149375_+|ROK-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224851
NC_017186.1|WP_013230999.1|10151869_10152682_+|hypothetical-protein	unknown	unknown	gnl|CDD|223021
NC_017186.1|WP_014467888.1|10150984_10151758_-|deoxyribonuclease-IV	unknown	unknown	gnl|CDD|179214

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017186.1|WP_013230990.1|10139570_10140659_-|inositol-3-phosphate-synthase	gnl|CDD|132491	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type. This enzyme, inositol 1-phosphate synthase as found in Actinobacteria, produces an essential precursor for several different products, including mycothiol, which is a glutathione analog, and phosphatidylinositol, which is a phospholipid.	0
NC_017186.1|WP_013230992.1|10141521_10141917_+|DUF5318-domain-containing-protein	gnl|CDD|379953	pfam17249, DUF5318, Family of unknown function (DUF5318). This family of unknown function is mostly found in Actinobacteria.	2.03166e-85
NC_017186.1|WP_013230997.1|10149423_10150974_+|DUF2029-domain-containing-protein	gnl|CDD|227937	COG5650, COG5650, Predicted integral membrane protein [Function unknown].	4.06087e-90
NC_017186.1|WP_013230989.1|10138948_10139467_-|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.61075e-32
NC_017186.1|WP_013231003.1|10155153_10155669_+|single-stranded-DNA-binding-protein	gnl|CDD|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	7.68256e-96
NC_017186.1|WP_013230986.1|10137097_10137556_-|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.97941e-15
NC_017186.1|WP_013230985.1|10135890_10137108_-|MFS-transporter	gnl|CDD|341027	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis multidrug efflux protein YfmO, bacillibactin exporter YmfD/YmfE, uncharacterized MFS-type transporter YvmA, and similar proteins. YfmO acts to efflux copper or a copper complex, and could contribute to copper resistance. YmfD/YmfE is involved in secretion of bacillibactin. The YfmO-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.04787e-76
NC_017186.1|WP_013230995.1|10147214_10148261_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|183212	PRK11579, PRK11579, putative oxidoreductase; Provisional.	3.53935e-93
NC_017186.1|WP_013230991.1|10140731_10141277_-|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.39252e-16
NC_017186.1|WP_176742060.1|10152799_10153705_+|hypothetical-protein	gnl|CDD|236362	PRK09010, PRK09010, single-stranded DNA-binding protein; Provisional.	0.00514585
NC_017186.1|WP_013230983.1|10131973_10133593_-|carboxypeptidase-regulatory-like-domain-containing-protein	gnl|CDD|375050	pfam17210, SdrD_B, SdrD B-like domain. This family corresponds to the B-like domain from the SdrD protein. This domain has three calcium binding sites within a greek key beta sandwich fold.	9.02993e-41
NC_017186.1|WP_013230987.1|10137622_10138261_+|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	2.29848e-48
NC_017186.1|WP_176742059.1|10154809_10155136_+|30S-ribosomal-protein-S6	gnl|CDD|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	1.6518e-38
NC_017186.1|WP_013230984.1|10133715_10135782_-|PhoX-family-protein	gnl|CDD|253386	pfam05787, DUF839, Bacterial protein of unknown function (DUF839). This family consists of several bacterial proteins of unknown function that contain a predicted beta-propeller repeats.	2.94794e-172
NC_017186.1|WP_013230994.1|10144784_10147139_+|penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	7.4926e-119
NC_017186.1|WP_013230996.1|10148316_10149375_+|ROK-family-transcriptional-regulator	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	4.90218e-36
NC_017186.1|WP_013230999.1|10151869_10152682_+|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.000291087
NC_017186.1|WP_014467888.1|10150984_10151758_-|deoxyribonuclease-IV	gnl|CDD|179214	PRK01060, PRK01060, endonuclease IV; Provisional.	4.38873e-105

Protein sequences

>NC_017186.1|WP_013230992.1|10141521_10141917_+|DUF5318-domain-containing-protein
MINQRQVVDYALQRRALLAEVRSGRVGSYEACDASPYLLRAAKFHGRDGDLPCPICRQEPLTLVSWVYGDELKHVAGSAKTPEELARMAGSFAEFTVYDVEVCRACHWNHLVRSYVLGTGEPASPRRNAGR
>NC_017186.1|WP_013230991.1|10140731_10141277_-|PadR-family-transcriptional-regulator
MLEFAILGLLHEAPMHGYVLRKRLHETLGTFRTFSYGSLYPTLRKLLRAGYLVEELDEADDRAWSRRGRRVYKLTAEGKERFGELLGDAGPQTWDDEGFGVHLAFFSRTPADVRLRILEGRRRRVEERREGMRAALARAEEKIDRYTRELHRLGLETSEREVRWLNELIAHEQAERQGPET
>NC_017186.1|WP_013230990.1|10139570_10140659_-|inositol-3-phosphate-synthase
MGENRRVRVAIVGVGNCAASLVQGVQYYRDADPANRVPGLMHVDFGGYHVRDIEFVAAFDVDAKKVSRDLSEAIFASENNTIKIADVPPLGVTVQRGHTHDGLGRFYRETIEESDETPVDIVAALREAKADVLVSYLPVGSEVADKFYAQAAIDAGVAFVNALPVFIASDPEWAQKFTDAGVPIVGDDIKSQVGATITHRVLAKLFEDRGVQLDRTMQLNVGGNMDFLNMKELERLESKKISKTQSVTSQVDRDLGKGNVHIGPSDYVQWLDDRKWAYVRLEGRAFGDVPLNLEYKLEVWDSPNSAGIIIDAVRAAKIALDRGIGGPILSASSYFMKSPPEQYDDATARDAVEKFIRGEVER
>NC_017186.1|WP_013230989.1|10138948_10139467_-|SigE-family-RNA-polymerase-sigma-factor
MGESAPGDLGVPTFHDLFREYFGQMTRLAHLLGADDAENVAQEAFVKLHQRWDSLTDHSRVAGYLRTIVVNMSRSRTRHLRVVRRTPQDRPPDELSAEVRAVANWEHQRLRAVLVRLSRRQREVLVLRYWLDLSTAAIAETLGISQGTVKATTHHAMENLRKHLGDDLGGER
>NC_017186.1|WP_013230988.1|10138253_10138952_-|hypothetical-protein
MTDLERKLAETLREQAGEVTPNLDAAWAEQQRRQQRRPRRRRAAVWGAPLAAVLVVLTSVLLATQVNTGQAPPPAAHPGEPLVLPKPEYLTLSALQVTDTPAVITTFAGQSNTWSTYVFTATVAGAPRFCLAAVPRGDQLIPDAPQYGTKSPLCMPIADRGDLLAGYVGEDGGPLPAGKAVYVVDPRRRADLRLFDAAGNLSQPQSDANVGDYLAYLTDVNPGSPPVRFEVS
>NC_017186.1|WP_013230987.1|10137622_10138261_+|HAD-family-phosphatase
MDAVIFDLDGVLVDSERIWDEVRRAVVAEHGGTWRDEATRALQGMSTPEWARYLVEELGAQLTPPEIATLVVKRMAARYAEEPPLIPGAVDVVRQVSARWPVAIASSSPVILIKGFLDVTGLPVGAAVSSEQVGAGKPAPDVYLRAAELLGVAPSECAAVEDTTNGLRSALAAGMAVYAVPNPHFPPDPEVLKQATAVVEKITDLPGALGLS
>NC_017186.1|WP_013230986.1|10137097_10137556_-|MarR-family-transcriptional-regulator
MTSAITDLAHRLRPLVFRLYHQVRRQTPQLTLTLTQGSVLSELVNGGPRRMSALAEFERVKLPSMTDVVGRLERLGLATRRPDPADGRAVLVEVTDEGLRFYAELVTAREEFLRERLIAMDDTDRAAIEAALPALAKLLVDAKKEALISDER
>NC_017186.1|WP_013230985.1|10135890_10137108_-|MFS-transporter
MSAEHHSSLLDAVKGQPKQVWITAFAAVIAFMGIGLVDPILLSIAKGLDATPSQVTLLFSSYLGVQVVAMLVTGAASARFGAKRTVLAGLTLIVAATALCAAAGSIEQLVGLRAVWGLGNAFFIATALSVIVGAATGGQSGAILLYEAALGVGLSVGPLLGALLGSISWRGPFLGTAILMAGALVLCAVFLKSDKHEKREPIKLLDPLRALKHTGLLRTSVASALYTAAFFAVLAWSPFVLGWSAIAVGLVFCGWGLCVAVAGVALAPRLAARLGERHAAAAAVFGYAVLMLVLAVPSKPVLVAGIIVSGLVSGLLNTLFTGTAMSISEAPRPVASAGYNFCRWLGGAVAATLVGHVAEWFGSPQAPFVASAVLCVVAGALLSLREKKADPHTLPKEAVLVGEEF
>NC_017186.1|WP_013230984.1|10133715_10135782_-|PhoX-family-protein
MLDRLLPLFPAHPGGRSPVTCEYRCGNACAHPEANETDNEYFGDVVKDISRRRVFKAGAVMAAAAGGFAALSGTAAAAPAAPAPRPPRPVPGTDFTPVPPNKLDAVSIPDGYAQRVVVRWGDPVVAGAPKFDFTNQTAAAQAKQFGYNNDFVGLIPQDPLGLSNLLVVNHEYTTEVHMFPAGQYDPANPTEEQAKIAWAAHGLSVLQARRDPIHGGLEVVPSRYGRRITLDTIFEVRGPAAGSKFLQTSADPSGRKVRGTQNNCSGGVTPWGTVLSGEENFDQYFANSDKVTDPVAAARLKRYSVGAGPSTRKWERFDKRWDVSQEPNEPNRFGWVVEIDPNDPDSTPVKHTALGRFKHEAANIKITADGRVAVYSGDDSRFEYIYKFVSKGKYKPGTSAHARRHNSALLDEGTLYVGRFTGDSPAAEIDGKGTLPADGEFDGTGEWIPLVSGDKSFVDGFTAEEVYVFTRQAADKVAATKMDRPEDIEPNPVNGRIYAALTNNSDRGATGKAGVDEPNPRVGNKNGHILEWEEDCGDAASTRFSWRLLLVCGDPQAADTYFGGFPKDQVSPISCPDNVAFDRHGNLWIATDGNALGANDGLFSVPVTGPERGHVKQFLSVPVGAETCGPVVTDNLVLVAVQHPGENATSSANPTSHWPDGGTAQPRPAIVSVWKKGRFGLPGRIGER
>NC_017186.1|WP_013230983.1|10131973_10133593_-|carboxypeptidase-regulatory-like-domain-containing-protein
MIFSRRTAAVAVVAIAAAVVPASASIAEDAPPVCGGLAANPSVELAARNGAPDGYVFAPAAPVPPGTPAAKVPKLLTEREYAVDGQRAAVVQTPDGKTSTAYQTERFVPGGVYGLSVWTASRAPRYEPATGLRFYDATGTQIQETKLVAGHYAGDGALVRQDFPAATAPSKAAAVKFFATTTLDRLHWDCVDLQLAAYSVKKEVQNPATGAWASFATVTAGETAHYRVTVTNEGTEDLTGITVQDPWCPGTFEPFALAAGANRQLTCDHPDLTVADSGHVNTAKVTGVRYPGGTLGDKTASATITVLPPPAIAKIGDFVWADRNRDGLQDPDEPGVAGVKVTLKDGAGGTIGTATTDDKGKYGFEKLKDGTYQVCFAVPADFTVTRRDAGSDDRDSDADPGGCTAPRTVGAPSHEDFAVDLGLLSPTNRIGDFAWADTNGNGVQDAGEPGLAGVKVVLKDASGKQVASVVTGSGGTYGFDGLADGTYQVCFTAEGRHPTARGVGDAARDSDADLVSGCAEPRTLGPAKREDRTVDVGFA
>NC_017186.1|WP_013230994.1|10144784_10147139_+|penicillin-binding-protein
MYTDRNRSRSGRRPVPRGRYQPRRPLPRLDEPDEPDDLATDVTPVPPPEPRNRRRWKTVRRVLYVLSGLFFLVPAVAFVITYFAVDVPSPDKVAQSQGQAVTYLYADGTEMGKDVPAGGNRQILDPAQIPDVVKKAVIATEDASFETNSGFDLSGIARAAYNQAIGGSGGGSTISQQYIKKATGDDAPTLTRKWVELAKSFKMNQTYEKADIITAYLNIIYFGRGAYGIQAAAQAYFGKDAAQLNYSEAALLAGLIQQPGRSENATVARDRWGTALDRMLRNGYLTAADRTAAKFPTPVPLVESRPGNKLNPFVKKQVKAELAAAGIPEEKYYSGGFQVFTTIDSKAQEAAEKAVAEGMAGQTDDRILDALVAVDPKSGGVLAYYGGEPIVKGPNGEDQAGRDWADEAHNPGSSMKPFDLTAFLKGGRGLNAVFDGRSPRTFPDVPLPVRNAGTTSSCSEQCTVAEAMQRSTNTVFYDMVLNVTKPGGVAEAAQEAGIRTKNTGGRSVLFTGDNNISIGGGQTAVTPADMAAGYATFAAGGVQHGRHFVQKVTNSQGETAYEANVRATDAFADNDRGKSRQIAGNVTAALAPVIPFSRLTCPPGHECAGKTGTQQHTPGTDEPASAANTNSQTWMVGYTPSVSAAVWVGGDGDKALHGPTGQPLTPSVVAGPVWQRFMQLYLTGKPAERFDRVQAITSPQDDQLQFQLQQQQQQQQFQQQQQQQQQQDQDQQEQRFTIGRGGNQDQQQQQQQQQNRVRRDGRGPGRGNGNDTGQSNTGQSNFGP
>NC_017186.1|WP_013230995.1|10147214_10148261_-|Gfo/Idh/MocA-family-oxidoreductase
MADDLRVGILGYGIGGRVFHAPLVAATPGLTPAVITTSSNAAQARIDHPGAEIVPDADALFERAGDLDLVVVSTPNRTHVPLALRAIEAGLPVVVDKPFAPTAAEAEQVVGAAKAAGVGLTVFQNRRLDSDFLTVRKVLDSGRLGEVFRFESRYDRWVPKPKDNWREFGDPAEAGGLLYDLGAHIVDQALQLFGPVTRVYAETDRRRAGVQVDDDVFVALHHANGVRSHLWATALAGTQNPRFRVLGDRATFTKYGLDVQEPQIKAGLRPGDAGWGTEPASDAGRLGVGPDVETVPTEVGRYEQFYAQVRDALRGEGEFPVDPASSVEALRVIEAAHRAGVEGTVVEL
>NC_017186.1|WP_013230996.1|10148316_10149375_+|ROK-family-transcriptional-regulator
MADTGVNLRDVREHNRALLLTHILRAGGLSRVELAERTGLTQQAVSKIVPELFDTGLLDEQRQPSAGVGKPRTALRIRAGAKHALGARLDRDEYRVLRANLVGEVEETAGGPLPPGFTPAQAVDAIGATARELADGFDVLGLGLGAVGPLDHLAGLVRDATNMPGWHDVPLRELLEQRTGLPVTLDKNTNAAAFARLWPHGEPTATAVVLVGTGIGVGLLIDGRLYRGPRTNAGEFGHTTIAYDGPRCACGRRGCVEIMAKQAPDTRTAAGFLGIGLADLVQVLDLERIVLAGRAVRDEPDVHREAVSARLEELLPLPHWQRIEVVEDASGEEIVTRGAAAEVLASYYANPA
>NC_017186.1|WP_013230997.1|10149423_10150974_+|DUF2029-domain-containing-protein
MPEETTREPEPGPVTLTRAERIVPSWNEPLAAAVTRPLGGPLGEHAAVGRHWFWSPQRVGLLLATLALMLCWFGKGSCIQQYQDSSGATQLDWRAGRPFVAMCYSDIVPLYGSERLDRPATFPYYTSWKESSQTAENNTRYMEYPVLTGLFQWANAKLAAGWLNVAETGWLPGALPVAIYFDITAFFLAVAWLVTVWATGRTMRRRPWDMVLVAISPLVLVHAFTNFDAIATAFTATGLLAWARKRPLLAGVLLGLGATAKLYPLFLLGVLFALCLRAGKLTPFWKTAGAAVVTWLAVNAPFILTATRGWWEFFRMSALRPMDPDSLYNVFSYTSGWAGFDGVLQKNQTPTYLNITVAVLFLTCCAGIAYLALAAPRRPRVGQLAFLVVAAFLLTNKVWSPQYSLWLVPLAVLAIPRWRLLLGWMLIDAVVWVPRMFYYLGVDHKGLPEGWFLGTVVVRDLAVIGLCVLVVREIYRPATDLVRMDGDDDPAGGFLDGARDVIIPNATRRRRKAVGV
>NC_017186.1|WP_014467888.1|10150984_10151758_-|deoxyribonuclease-IV
MLIGAHVRDDDPLPAVVERKAEVVQFFLSDPQGWKAPKPHPHGEAIKADPVEVFIHSPYLINVASLNNRIRIPSRKNVTQHADGAAAIGAKGLIVHGGHVGANDDAEAGLDNWRKLFEREQEKGGFKVPILIENTAGGENAMTRDLDVIARLWDKVGEFGAGFCLDTCHAFAAGWDLATAVGRVKAITGRIDLVHLNNSRDEFGSTRDRHANVVQGDGTIDPEVLVAVAREAGAPVVVETPADGQAADIAYLREQLG
>NC_017186.1|WP_013230999.1|10151869_10152682_+|hypothetical-protein
MMGKHVTRITALGFTIAASAALAAPGVASADPSPTLGGDCQATLQQGSANGLVLDAGAPLNAPNQLTIGLDSSSRNTNGSAPLLTLPLGDTVKALGIGRVPLVGDAAAKGVCPVAQGTVNAVGNLTQGVAAELPPLPLPPAPGPKPPQPAPPTPPGPNPPSPGPGPNPPGSSTGPVVTGQGNAGLPGDAISGIFTNAALLPGSLVQAPVIAQIIPGQQVPPPTVDAERSGTAEALPAVTPPAKLPMLLAVLALAIVAAALVRAWIRRSPA
>NC_017186.1|WP_176742060.1|10152799_10153705_+|hypothetical-protein
MQDRTRRATAVGAAAVVLAGSAVLGLPGTASADTKTVPCGSTVDAKPGDHIQGSLLGLPLIDLGIVTQATTVLTTTVSGLLNTVCKVTVNVVNTVVSPVPVVGAPAASAINQGVQGVTSGTQQGLRSLSGGGQPAPQQPGGTGGNPQQPPAQGGSGGAPQQGGTPAGTMPIPDANSPLLPGFASTPVFGGFPFTLGTGYAPMRDYGGIPFATAGLFTPSPAIRYGSQIPGYAPQYGLTGPDGASDGNSGIQTAGQAEALPSASDGFTTGSNLPMLIAVLALSGVSAGLVRTWVLRRMAAGN
>NC_017186.1|WP_013231001.1|10153790_10154693_+|hypothetical-protein
MLVRKIPTWQTTRRALTLTAVAAFVTGGAFLSTGTASAATTLVSNSCTGSVTGQMGDQVAIDGASVKTLVTNGANNAGTLAVGSWAGDSIAKNHSIPVGQVPNSAGGEANGAAIGKAVRTALAASGTWGLGLDWNKTLNSVESTVAAGCGLTLLASNYVAPSTPAQQGSGSAVQQGGTGTAPGGASGNLSNLNPGTAGGTGGSAPMRDYSGIPTATAGTAVAPGVRYPANGTLPGDASAPQAGGGDQNGQGADIRDAGNAQSLASNSASNDVQLPMLIAVIVLAGVTAGLVRTWVLRRAA
>NC_017186.1|WP_176742059.1|10154809_10155136_+|30S-ribosomal-protein-S6
MSRHYEVMVILDPTLDERTVAPTLDTFLNVIRTSGGSVEKVDVWGRRRLSYEIKKHAEGIYALLDLNSSSDAVKELDRQLSLQETVLRTKVMRREVKRAAAKPAAAKA
>NC_017186.1|WP_013231003.1|10155153_10155669_+|single-stranded-DNA-binding-protein
MAGDTVITVVGNLTSDPELRFTPSGAAVANFTVASTPRTLDKQSGEWKDGEALFLRCNIWRQAAENVAESLTRGARVVVQGRLKQRSFETKEGEKRTVVELEVDEIGPSLRYATAKVNKVSRGGGGDFGGGGGGGGNRGGGGGGMPADDPWGSAPAASSGGGGGFSDEPPF

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	2183107-2183135	0	1.0
NC_017186_26	26.8|8280214|18|NC_017186|CRT	8280214-8280231	18	NC_017186.1	8280289-8280306	0	1.0
NC_017186_26	26.8|8280214|18|NC_017186|CRT	8280214-8280231	18	NC_017186.1	8280294-8280311	0	1.0
NC_017186_26	26.8|8280214|18|NC_017186|CRT	8280214-8280231	18	NC_017186.1	8280299-8280316	0	1.0
NC_017186_26	26.9|8280259|18|NC_017186|CRT	8280259-8280276	18	NC_017186.1	8280289-8280306	0	1.0
NC_017186_26	26.9|8280259|18|NC_017186|CRT	8280259-8280276	18	NC_017186.1	8280294-8280311	0	1.0
NC_017186_26	26.9|8280259|18|NC_017186|CRT	8280259-8280276	18	NC_017186.1	8280299-8280316	0	1.0
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	557412-557440	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	2916209-2916237	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	5989687-5989715	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	6196696-6196724	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	8163985-8164013	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	71547-71575	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	247667-247695	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	247727-247755	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	247788-247816	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	1133584-1133612	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	3315693-3315721	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	3320040-3320068	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	3377297-3377325	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	7397398-7397426	1	0.966
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	9965535-9965563	1	0.966
NC_017186_26	26.7|8280169|18|NC_017186|CRT	8280169-8280186	18	NC_017186.1	5200267-5200284	1	0.944
NC_017186_26	26.8|8280214|18|NC_017186|CRT	8280214-8280231	18	NC_017186.1	8307405-8307422	1	0.944
NC_017186_26	26.9|8280259|18|NC_017186|CRT	8280259-8280276	18	NC_017186.1	8307405-8307422	1	0.944
NC_017186_1	1.1|70655|26|NC_017186|CRISPRCasFinder	70655-70680	26	NC_017186.1	1133588-1133613	2	0.923
NC_017186_1	1.1|70655|26|NC_017186|CRISPRCasFinder	70655-70680	26	NC_017186.1	7397402-7397427	2	0.923
NC_017186_1	1.1|70655|26|NC_017186|CRISPRCasFinder	70655-70680	26	NC_017186.1	2681721-2681746	2	0.923
NC_017186_1	1.1|70655|26|NC_017186|CRISPRCasFinder	70655-70680	26	NC_017186.1	8888544-8888569	2	0.923
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	557286-557314	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	557349-557377	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	580730-580758	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	824870-824898	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	1455611-1455639	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	7434897-7434925	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	7627943-7627971	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	8429222-8429250	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	8927885-8927913	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	10032795-10032823	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	1842484-1842512	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	2167284-2167312	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	2497833-2497861	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	2613929-2613957	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	2817060-2817088	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	3537721-3537749	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	5078196-5078224	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	5780701-5780729	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	7298534-7298562	2	0.931
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_017186.1	8652672-8652700	2	0.931
NC_017186_26	26.4|8280011|19|NC_017186|CRT	8280011-8280029	19	NC_017186.1	2047133-2047151	2	0.895
NC_017186_26	26.4|8280011|19|NC_017186|CRT	8280011-8280029	19	NC_017186.1	4313863-4313881	2	0.895
NC_017186_26	26.4|8280011|19|NC_017186|CRT	8280011-8280029	19	NC_017186.1	5071229-5071247	2	0.895
NC_017186_26	26.4|8280011|19|NC_017186|CRT	8280011-8280029	19	NC_017186.1	7612726-7612744	2	0.895
NC_017186_26	26.6|8280108|34|NC_017186|CRT	8280108-8280141	34	NC_017186.1	8280273-8280306	2	0.941
NC_017186_26	26.6|8280108|34|NC_017186|CRT	8280108-8280141	34	NC_017186.1	8280278-8280311	2	0.941
NC_017186_26	26.6|8280108|34|NC_017186|CRT	8280108-8280141	34	NC_017186.1	8280283-8280316	2	0.941

1. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 2183107-2183135, mismatch: 0, identity: 1.0

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgagccggggg	Protospacer
*****************************

2. spacer 26.8|8280214|18|NC_017186|CRT matches to position: 8280289-8280306, mismatch: 0, identity: 1.0

tcggctcggctcggctcg	CRISPR spacer
tcggctcggctcggctcg	Protospacer
******************

3. spacer 26.8|8280214|18|NC_017186|CRT matches to position: 8280294-8280311, mismatch: 0, identity: 1.0

tcggctcggctcggctcg	CRISPR spacer
tcggctcggctcggctcg	Protospacer
******************

4. spacer 26.8|8280214|18|NC_017186|CRT matches to position: 8280299-8280316, mismatch: 0, identity: 1.0

tcggctcggctcggctcg	CRISPR spacer
tcggctcggctcggctcg	Protospacer
******************

5. spacer 26.9|8280259|18|NC_017186|CRT matches to position: 8280289-8280306, mismatch: 0, identity: 1.0

tcggctcggctcggctcg	CRISPR spacer
tcggctcggctcggctcg	Protospacer
******************

6. spacer 26.9|8280259|18|NC_017186|CRT matches to position: 8280294-8280311, mismatch: 0, identity: 1.0

tcggctcggctcggctcg	CRISPR spacer
tcggctcggctcggctcg	Protospacer
******************

7. spacer 26.9|8280259|18|NC_017186|CRT matches to position: 8280299-8280316, mismatch: 0, identity: 1.0

tcggctcggctcggctcg	CRISPR spacer
tcggctcggctcggctcg	Protospacer
******************

8. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 557412-557440, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

9. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 2916209-2916237, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

10. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 5989687-5989715, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

11. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 6196696-6196724, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

12. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 8163985-8164013, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaatcggggcttcgccccgagccggggg	Protospacer
****.************************

13. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 71547-71575, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

14. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 247667-247695, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

15. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 247727-247755, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

16. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 247788-247816, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

17. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 1133584-1133612, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgagccggggg	Protospacer
*** *************************

18. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 3315693-3315721, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

19. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 3320040-3320068, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

20. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 3377297-3377325, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

21. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 7397398-7397426, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgagccggggg	Protospacer
*** *************************

22. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 9965535-9965563, mismatch: 1, identity: 0.966

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccgggccggggg	Protospacer
********************.********

23. spacer 26.7|8280169|18|NC_017186|CRT matches to position: 5200267-5200284, mismatch: 1, identity: 0.944

ccagctcggcccagctcg	CRISPR spacer
ccagctcggcccagcgcg	Protospacer
*************** **

24. spacer 26.8|8280214|18|NC_017186|CRT matches to position: 8307405-8307422, mismatch: 1, identity: 0.944

tcggctcggctcggctcg	CRISPR spacer
tcggctcagctcggctcg	Protospacer
*******.**********

25. spacer 26.9|8280259|18|NC_017186|CRT matches to position: 8307405-8307422, mismatch: 1, identity: 0.944

tcggctcggctcggctcg	CRISPR spacer
tcggctcagctcggctcg	Protospacer
*******.**********

26. spacer 1.1|70655|26|NC_017186|CRISPRCasFinder matches to position: 1133588-1133613, mismatch: 2, identity: 0.923

cggctcggggcgaagccctggaggtc	CRISPR spacer
cggctcggggcgaagccccggatgtc	Protospacer
******************.*** ***

27. spacer 1.1|70655|26|NC_017186|CRISPRCasFinder matches to position: 7397402-7397427, mismatch: 2, identity: 0.923

cggctcggggcgaagccctggaggtc	CRISPR spacer
cggctcggggcgaagccccggatgtc	Protospacer
******************.*** ***

28. spacer 1.1|70655|26|NC_017186|CRISPRCasFinder matches to position: 2681721-2681746, mismatch: 2, identity: 0.923

cggctcggggcgaagccctggaggtc	CRISPR spacer
cggcccggggcgaagccccggaggtc	Protospacer
****.*************.*******

29. spacer 1.1|70655|26|NC_017186|CRISPRCasFinder matches to position: 8888544-8888569, mismatch: 2, identity: 0.923

cggctcggggcgaagccctggaggtc	CRISPR spacer
cggctcggggcgaagccccggatgtc	Protospacer
******************.*** ***

30. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 557286-557314, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcgtcgccccgggccggggg	Protospacer
*********** ********.********

31. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 557349-557377, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggctttgccccgggccggggg	Protospacer
*************.******.********

32. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 580730-580758, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggctccgccccgggccggggg	Protospacer
************.*******.********

33. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 824870-824898, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggctccgccccgggccggggg	Protospacer
************.*******.********

34. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 1455611-1455639, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgggccggggg	Protospacer
*** ****************.********

35. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 7434897-7434925, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgacccggggg	Protospacer
*** ***************** *******

36. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 7627943-7627971, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acattcggggcttcgccccgagccggggg	Protospacer
*** .************************

37. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 8429222-8429250, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgggccggggg	Protospacer
*** ****************.********

38. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 8927885-8927913, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgggccggggg	Protospacer
*** ****************.********

39. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 10032795-10032823, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggctccgccccgagccggggg	Protospacer
*** ********.****************

40. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 1842484-1842512, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccctgggccggggg	Protospacer
******************.*.********

41. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 2167284-2167312, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgggccggggg	Protospacer
*** ****************.********

42. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 2497833-2497861, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccgaggcttcgccccgggccggggg	Protospacer
*******.************.********

43. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 2613929-2613957, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
accaccggggcttcgccccgggccggggg	Protospacer
** *****************.********

44. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 2817060-2817088, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggctccgccccgggccggggg	Protospacer
************.*******.********

45. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 3537721-3537749, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggcttcgccccaggccggggg	Protospacer
*******************..********

46. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 5078196-5078224, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggctccgccccgggccggggg	Protospacer
************.*******.********

47. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 5780701-5780729, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggggctccgccccgggccggggg	Protospacer
************.*******.********

48. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 7298534-7298562, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acatccggggcttcgccccgggccggggg	Protospacer
*** ****************.********

49. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to position: 8652672-8652700, mismatch: 2, identity: 0.931

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccggagcttcgccccgggccggggg	Protospacer
********.***********.********

50. spacer 26.4|8280011|19|NC_017186|CRT matches to position: 2047133-2047151, mismatch: 2, identity: 0.895

ccggctcgccctgggctgg	CRISPR spacer
ccggctcgccctcggcggg	Protospacer
************ *** **

51. spacer 26.4|8280011|19|NC_017186|CRT matches to position: 4313863-4313881, mismatch: 2, identity: 0.895

ccggctcgccctgggctgg	CRISPR spacer
ccggctcgccatcggctgg	Protospacer
********** * ******

52. spacer 26.4|8280011|19|NC_017186|CRT matches to position: 5071229-5071247, mismatch: 2, identity: 0.895

ccggctcgccctgggctgg	CRISPR spacer
ccggctcgacctgggcggg	Protospacer
******** ******* **

53. spacer 26.4|8280011|19|NC_017186|CRT matches to position: 7612726-7612744, mismatch: 2, identity: 0.895

ccggctcgccctgggctgg	CRISPR spacer
ccggctcgcctcgggctgg	Protospacer
**********..*******

54. spacer 26.6|8280108|34|NC_017186|CRT matches to position: 8280273-8280306, mismatch: 2, identity: 0.941

ctgggttcggctcggctcggctcggctcggctcg	CRISPR spacer
ctcggctcggctcggctcggctcggctcggctcg	Protospacer
** **.****************************

55. spacer 26.6|8280108|34|NC_017186|CRT matches to position: 8280278-8280311, mismatch: 2, identity: 0.941

ctgggttcggctcggctcggctcggctcggctcg	CRISPR spacer
ctcggctcggctcggctcggctcggctcggctcg	Protospacer
** **.****************************

56. spacer 26.6|8280108|34|NC_017186|CRT matches to position: 8280283-8280316, mismatch: 2, identity: 0.941

ctgggttcggctcggctcggctcggctcggctcg	CRISPR spacer
ctcggctcggctcggctcggctcggctcggctcg	Protospacer
** **.****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017186_1	1.1|70655|26|NC_017186|CRISPRCasFinder	70655-70680	26	MN693271	Marine virus AFVG_25M119, complete genome	12142-12167	3	0.885
NC_017186_5	5.2|1356941|25|NC_017186|CRT	1356941-1356965	25	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	101129-101153	3	0.88
NC_017186_5	5.3|1356984|24|NC_017186|CRT	1356984-1357007	24	MH825706	Streptomyces phage Microdon, complete genome	33975-33998	3	0.875
NC_017186_5	5.3|1356984|24|NC_017186|CRT	1356984-1357007	24	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	514325-514348	3	0.875
NC_017186_5	5.2|1356941|25|NC_017186|CRT	1356941-1356965	25	MN035621	Leviviridae sp. isolate H1_Bulk_29_scaffold_509 RNA-dependent RNA polymerase (H1Bulk29509_000001) gene, partial cds; hypothetical protein (H1Bulk29509_000002) and hypothetical protein (H1Bulk29509_000003) genes, complete cds; and hypothetical protein (H1Bulk29509_000004) gene, partial cds	892-916	4	0.84
NC_017186_5	5.2|1356941|25|NC_017186|CRT	1356941-1356965	25	MN034612	Leviviridae sp. isolate H4_Bulk_48_scaffold_2658 sequence	563-587	4	0.84
NC_017186_5	5.2|1356941|25|NC_017186|CRT	1356941-1356965	25	MN034028	Leviviridae sp. isolate H2_Rhizo_Litter_49_scaffold_1266 hypothetical protein (H2RhizoLitter491266_000001) gene, partial cds; hypothetical protein (H2RhizoLitter491266_000002) and hypothetical protein (H2RhizoLitter491266_000003) genes, complete cds; and RNA-dependent RNA polymerase (H2RhizoLitter491266_000004) gene, partial cds	2708-2732	4	0.84
NC_017186_8	8.13|2088351|27|NC_017186|PILER-CR	2088351-2088377	27	NZ_KY362371	Pseudomonas syringae pv. syringae strain UMAF1029 plasmid pPs1029, complete sequence	13399-13425	4	0.852
NC_017186_8	8.13|2088351|27|NC_017186|PILER-CR	2088351-2088377	27	NZ_KY362370	Pseudomonas syringae pv. syringae strain UMAF0158 plasmid pPs0158, complete sequence	13392-13418	4	0.852
NC_017186_8	8.13|2088351|27|NC_017186|PILER-CR	2088351-2088377	27	NZ_CP005971	Pseudomonas syringae UMAF0158 plasmid unnamed, complete sequence	40588-40614	4	0.852
NC_017186_8	8.14|2088417|26|NC_017186|PILER-CR	2088417-2088442	26	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1912353-1912378	4	0.846
NC_017186_8	8.14|2088417|26|NC_017186|PILER-CR	2088417-2088442	26	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	702367-702392	4	0.846
NC_017186_8	8.14|2088417|26|NC_017186|PILER-CR	2088417-2088442	26	NZ_CP021082	Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence	366054-366079	4	0.846
NC_017186_5	5.3|1356984|24|NC_017186|CRT	1356984-1357007	24	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	881770-881793	5	0.792
NC_017186_8	8.14|2088417|26|NC_017186|PILER-CR	2088417-2088442	26	NZ_CP020372	Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence	466884-466909	5	0.808
NC_017186_8	8.14|2088417|26|NC_017186|PILER-CR	2088417-2088442	26	NC_011143	Phenylobacterium zucineum HLK1 plasmid, complete sequence	98292-98317	5	0.808
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP041018	Sphingobium fuliginis ATCC 27551 plasmid pSF1, complete sequence	125922-125950	5	0.828
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	655593-655621	5	0.828
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP033227	Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence	467139-467167	5	0.828
NC_017186_20	20.4|6438632|32|NC_017186|CRISPRCasFinder	6438632-6438663	32	NZ_CP027859	Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence	776199-776230	5	0.844
NC_017186_20	20.4|6438632|32|NC_017186|CRISPRCasFinder	6438632-6438663	32	NZ_CP032054	Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence	377968-377999	5	0.844
NC_017186_20	20.4|6438632|32|NC_017186|CRISPRCasFinder	6438632-6438663	32	NZ_CP016560	Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence	35225-35256	5	0.844
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	223493-223521	5	0.828
NC_017186_3	3.1|763149|30|NC_017186|CRISPRCasFinder	763149-763178	30	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	38222-38251	6	0.8
NC_017186_3	3.1|763149|30|NC_017186|CRISPRCasFinder	763149-763178	30	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1724128-1724157	6	0.8
NC_017186_8	8.14|2088417|26|NC_017186|PILER-CR	2088417-2088442	26	NC_021911	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence	229992-230017	6	0.769
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP047174	Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence	14816-14844	6	0.793
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	NZ_CP032686	Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence	374920-374949	6	0.8
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	NZ_CP032691	Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence	366237-366266	6	0.8
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	NZ_CP045331	Labrenzia sp. THAF191b plasmid pTHAF191b_c, complete sequence	37880-37909	6	0.8
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	NZ_CP045347	Labrenzia sp. THAF187b plasmid pTHAF187b_c, complete sequence	15563-15592	6	0.8
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	NZ_CP045336	Labrenzia sp. THAF191a plasmid pTHAF191a_c, complete sequence	86755-86784	6	0.8
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	NZ_CP045382	Labrenzia sp. THAF35 plasmid pTHAF35_b, complete sequence	16356-16385	6	0.8
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	828351-828379	6	0.793
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013589	Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence	817101-817129	6	0.793
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	803642-803670	6	0.793
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	795709-795737	6	0.793
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	816286-816314	6	0.793
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013546	Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence	810037-810065	6	0.793
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	828351-828379	6	0.793
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	795709-795737	6	0.793
NC_017186_19	19.6|6437107|30|NC_017186|CRISPRCasFinder	6437107-6437136	30	NZ_CP032326	Azospirillum brasilense strain MTCC4035 plasmid p5, complete sequence	29558-29587	6	0.8
NC_017186_19	19.7|6437166|32|NC_017186|CRISPRCasFinder	6437166-6437197	32	MH834621	Arthrobacter phage Nandita, complete genome	39366-39397	6	0.812
NC_017186_19	19.7|6437166|32|NC_017186|CRISPRCasFinder	6437166-6437197	32	MH834627	Arthrobacter phage Ryan, complete genome	39919-39950	6	0.812
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NC_011892	Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence	164897-164928	6	0.812
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP029211	Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence	112956-112987	6	0.812
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	153754-153785	6	0.812
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	806477-806508	6	0.812
NC_017186_21	21.4|6441628|32|NC_017186|CRISPRCasFinder	6441628-6441659	32	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	228115-228146	6	0.812
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	MH576973	Mycobacterium phage Bromden, complete genome	33544-33575	6	0.812
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	42490-42518	6	0.793
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NZ_CP026653	Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence	36000-36028	6	0.793
NC_017186_2	2.1|301050|29|NC_017186|CRISPRCasFinder	301050-301078	29	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	79162-79190	7	0.759
NC_017186_3	3.1|763149|30|NC_017186|CRISPRCasFinder	763149-763178	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2568889-2568918	7	0.767
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP011600	Phytobacter ursingii strain CAV1151 plasmid pCAV1151-215, complete sequence	23957-23985	7	0.759
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_AP018757	Metakosakonia sp. MRY16-398 plasmid pMRY16-398_1, complete sequence	180725-180753	7	0.759
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	1448785-1448813	7	0.759
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	543079-543107	7	0.759
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP021805	Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence	168724-168752	7	0.759
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP021217	Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence	979876-979904	7	0.759
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	MH632120	Mycobacterium phage Thonko, complete genome	40740-40768	7	0.759
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	AP018479	Mycobacterium phage GS4E DNA, complete sequence	31302-31331	7	0.767
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	MT310877	Mycobacterium phage VA6, complete genome	31169-31198	7	0.767
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	MT658804	Mycobacterium phage BengiVuitton, complete genome	31277-31306	7	0.767
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	NC_023597	Mycobacterium phage 20ES, complete genome	31315-31344	7	0.767
NC_017186_19	19.1|6436809|30|NC_017186|CRISPRCasFinder	6436809-6436838	30	MT310886	Mycobacterium phage AN3, complete genome	31695-31724	7	0.767
NC_017186_19	19.3|6436928|32|NC_017186|CRISPRCasFinder	6436928-6436959	32	NC_015583	Novosphingobium sp. PP1Y plasmid Mpl, complete sequence	305125-305156	7	0.781
NC_017186_19	19.4|6436989|29|NC_017186|CRISPRCasFinder	6436989-6437017	29	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	262957-262985	7	0.759
NC_017186_19	19.10|6437349|32|NC_017186|CRISPRCasFinder	6437349-6437380	32	KY555145	Caulobacter phage Ccr29, complete genome	183233-183264	7	0.781
NC_017186_19	19.10|6437349|32|NC_017186|CRISPRCasFinder	6437349-6437380	32	KY555143	Caulobacter phage Ccr2, complete genome	176380-176411	7	0.781
NC_017186_19	19.10|6437349|32|NC_017186|CRISPRCasFinder	6437349-6437380	32	KY555142	Caulobacter phage Ccr10, complete genome	175905-175936	7	0.781
NC_017186_20	20.3|6438753|33|NC_017186|PILER-CR,CRT	6438753-6438785	33	NC_011892	Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence	164897-164929	7	0.788
NC_017186_20	20.3|6438753|33|NC_017186|PILER-CR,CRT	6438753-6438785	33	NZ_CP029211	Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence	112955-112987	7	0.788
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP040937	Hymenobacter sp. DG01 plasmid unnamed, complete sequence	120777-120808	7	0.781
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP028350	Pantoea vagans strain PV989 plasmid pPV989-508, complete sequence	384430-384461	7	0.781
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NC_014258	Pantoea vagans C9-1 plasmid pPag3, complete sequence	187504-187535	7	0.781
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP038854	Pantoea vagans strain LMG 24199 plasmid unnamed1, complete sequence	351464-351495	7	0.781
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP006588	Hymenobacter sp. APR13 plasmid pHA, complete sequence	107286-107317	7	0.781
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP010410	Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence	66006-66037	7	0.781
NC_017186_21	21.2|6441506|32|NC_017186|CRISPRCasFinder	6441506-6441537	32	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	155273-155304	7	0.781
NC_017186_21	21.2|6441506|32|NC_017186|CRISPRCasFinder	6441506-6441537	32	NC_008441	Streptomyces laurentii plasmid pSLS DNA, complete sequence	2186-2217	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK919470	Gordonia phage Mellie, complete genome	14250-14281	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MN234179	Gordonia phage Pipp, complete genome	14483-14514	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MN010762	Gordonia phage MintFen, complete genome	14489-14520	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MT553336	Gordonia phage BlingBling, complete genome	14489-14520	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_031265	Gordonia phage Guacamole, complete genome	14493-14524	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MF919521	Gordonia phage Lysidious, complete genome	15013-15044	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MN369740	Gordonia phage Delian, complete genome	14513-14544	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK801724	Gordonia phage PhrostedPhlake, complete genome	14865-14896	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MH576969	Gordonia phage Zarbodnamra, complete genome	14488-14519	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK864263	Gordonia phage Melba, complete genome	14489-14520	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MN062704	Gordonia phage JuJu, complete genome	14417-14448	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK878896	Gordonia phage Begonia, complete genome	15021-15052	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK501729	Gordonia phage Walrus, complete genome	14712-14743	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MT723942	Gordonia phage Archis, complete genome	14700-14731	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK967389	Gordonia phage JasperJr, complete genome	14493-14524	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK501730	Gordonia phage Barco, complete genome	14489-14520	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	KU963251	Gordonia phage UmaThurman, complete genome	14617-14648	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	KX557274	Gordonia phage CaptainKirk2, complete genome	14513-14544	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MT723936	Gordonia phage Hitter, complete genome	14489-14520	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_031237	Gordonia phage Obliviate, complete genome	14279-14310	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_030921	Gordonia phage Utz, complete genome	14484-14515	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MN585963	Gordonia phage Wocket, complete genome	14730-14761	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1639653-1639684	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MK977705	Gordonia Phage Mollymur, complete genome	26365-26396	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP023450	Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p1, complete sequence	112681-112712	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP010956	Sphingobium sp. YBL2 plasmid 2pYBL2-2, complete sequence	40657-40688	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_015595	Sphingobium chlorophenolicum L-1 plasmid pSPHCH01, complete sequence	94934-94965	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP018225	Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL4, complete sequence	133327-133358	7	0.781
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP013265	Sphingobium baderi strain DE-13 plasmid pDE1, complete sequence	147979-148010	7	0.781
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	89759-89790	7	0.781
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	118065-118096	7	0.781
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP047175	Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence	68376-68407	7	0.781
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	217471-217502	7	0.781
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	153753-153785	7	0.788
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	806477-806509	7	0.788
NC_017186_21	21.8|6441505|33|NC_017186|CRT	6441505-6441537	33	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	155273-155305	7	0.788
NC_017186_21	21.8|6441505|33|NC_017186|CRT	6441505-6441537	33	NC_008441	Streptomyces laurentii plasmid pSLS DNA, complete sequence	2186-2218	7	0.788
NC_017186_21	21.10|6441627|33|NC_017186|CRT	6441627-6441659	33	NZ_CP044079	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence	228115-228147	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK919470	Gordonia phage Mellie, complete genome	14249-14281	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MN234179	Gordonia phage Pipp, complete genome	14482-14514	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MN010762	Gordonia phage MintFen, complete genome	14488-14520	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MT553336	Gordonia phage BlingBling, complete genome	14488-14520	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	NC_031265	Gordonia phage Guacamole, complete genome	14492-14524	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MF919521	Gordonia phage Lysidious, complete genome	15012-15044	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MN369740	Gordonia phage Delian, complete genome	14512-14544	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK801724	Gordonia phage PhrostedPhlake, complete genome	14864-14896	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MH576969	Gordonia phage Zarbodnamra, complete genome	14487-14519	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK864263	Gordonia phage Melba, complete genome	14488-14520	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MN062704	Gordonia phage JuJu, complete genome	14416-14448	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK878896	Gordonia phage Begonia, complete genome	15020-15052	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK501729	Gordonia phage Walrus, complete genome	14711-14743	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MT723942	Gordonia phage Archis, complete genome	14699-14731	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK967389	Gordonia phage JasperJr, complete genome	14492-14524	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK501730	Gordonia phage Barco, complete genome	14488-14520	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	KU963251	Gordonia phage UmaThurman, complete genome	14616-14648	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	KX557274	Gordonia phage CaptainKirk2, complete genome	14512-14544	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MT723936	Gordonia phage Hitter, complete genome	14488-14520	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	NC_031237	Gordonia phage Obliviate, complete genome	14278-14310	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	NC_030921	Gordonia phage Utz, complete genome	14483-14515	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MN585963	Gordonia phage Wocket, complete genome	14729-14761	7	0.788
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MK977705	Gordonia Phage Mollymur, complete genome	26364-26396	7	0.788
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	118064-118096	7	0.788
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_CP047175	Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence	68376-68408	7	0.788
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	760058-760089	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	945478-945509	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	745525-745556	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	341963-341994	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	753771-753802	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	743276-743307	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	547395-547426	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1411474-1411505	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	1097748-1097779	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	1005014-1005045	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	664273-664304	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	667148-667179	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	183730-183761	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1532250-1532281	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	264021-264052	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	904879-904910	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	766592-766623	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1116649-1116680	7	0.781
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	891013-891044	7	0.781
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP035092	Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence	400767-400798	7	0.781
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NC_008688	Paracoccus denitrificans PD1222 plasmid 1, complete sequence	648115-648146	7	0.781
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_LR134468	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence	116395-116426	7	0.781
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP023000	Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence	284959-284990	7	0.781
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_023285	Streptomyces sp. F8 plasmid pFRL5, complete sequence	125872-125900	7	0.759
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NC_011962	Rhodobacter sphaeroides KD131 plasmid pRSKD131A, complete sequence	80702-80730	7	0.759
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NZ_CP020810	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed1, complete sequence	48805-48833	7	0.759
NC_017186_25	25.1|6961022|29|NC_017186|CRISPRCasFinder	6961022-6961050	29	NZ_CP020041	Streptomyces sp. 3211 isolate 3 plasmid p3211-2, complete sequence	185933-185961	7	0.759
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	1548757-1548785	8	0.724
NC_017186_19	19.2|6436868|31|NC_017186|CRISPRCasFinder	6436868-6436898	31	NZ_CP012899	Burkholderia sp. CCGE1001 plasmid pCCGE1001a, complete sequence	62996-63026	8	0.742
NC_017186_19	19.2|6436868|31|NC_017186|CRISPRCasFinder	6436868-6436898	31	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	99375-99405	8	0.742
NC_017186_19	19.5|6437047|31|NC_017186|CRISPRCasFinder	6437047-6437077	31	NZ_CP013071	Sphingobium indicum B90A plasmid pSRL1, complete sequence	67357-67387	8	0.742
NC_017186_19	19.5|6437047|31|NC_017186|CRISPRCasFinder	6437047-6437077	31	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	1439111-1439141	8	0.742
NC_017186_19	19.10|6437349|32|NC_017186|CRISPRCasFinder	6437349-6437380	32	NZ_CP024312	Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence	254232-254263	8	0.75
NC_017186_19	19.11|6437410|32|NC_017186|CRISPRCasFinder	6437410-6437441	32	NC_006362	Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence	19765-19796	8	0.75
NC_017186_19	19.11|6437410|32|NC_017186|CRISPRCasFinder	6437410-6437441	32	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	247073-247104	8	0.75
NC_017186_19	19.11|6437410|32|NC_017186|CRISPRCasFinder	6437410-6437441	32	NZ_CP045303	Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence	154456-154487	8	0.75
NC_017186_20	20.3|6438753|33|NC_017186|PILER-CR,CRT	6438753-6438785	33	AF069529	Bacteriophage HK97, complete genome	18138-18170	8	0.758
NC_017186_20	20.3|6438753|33|NC_017186|PILER-CR,CRT	6438753-6438785	33	NC_002167	Enterobacteria phage HK97, complete genome	18138-18170	8	0.758
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	AF069529	Bacteriophage HK97, complete genome	18138-18169	8	0.75
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NC_002167	Enterobacteria phage HK97, complete genome	18138-18169	8	0.75
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	1930153-1930184	8	0.75
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	1697151-1697182	8	0.75
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP040824	Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence	79626-79657	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MK494119	Mycobacterium Phage Niklas, complete genome	30633-30664	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MK310138	Mycobacterium phage Shaobing, complete genome	30630-30661	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MF185722	Mycobacterium phage Peanam, complete genome	30630-30661	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1451013-1451044	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	150957-150988	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP048634	Rhizobium oryzihabitans strain M15 plasmid p2, complete sequence	12138-12169	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP048638	Rhizobium oryzihabitans strain M15 plasmid p6, complete sequence	48929-48960	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP048639	Rhizobium oryzihabitans strain M15 plasmid p7, complete sequence	12902-12933	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1473723-1473754	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MN096355	Mycobacterium phage Purky, complete genome	5817-5848	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MK016499	Mycobacterium phage Mangethe, complete genome	5845-5876	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MK919480	Mycobacterium phage Techage, complete genome	5848-5879	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MF919492	Mycobacterium phage Arib1, complete genome	5845-5876	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NC_041969	Mycobacterium phage Jebeks, complete genome	5845-5876	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NC_023552	Mycobacterium phage Donovan, complete genome	5845-5876	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MN693323	Marine virus AFVG_25M87, complete genome	11504-11535	8	0.75
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MF472894	Mycobacterium phage Majeke, complete genome	5845-5876	8	0.75
NC_017186_21	21.2|6441506|32|NC_017186|CRISPRCasFinder	6441506-6441537	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1606082-1606113	8	0.75
NC_017186_21	21.2|6441506|32|NC_017186|CRISPRCasFinder	6441506-6441537	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	207179-207210	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_031230	Gordonia phage Yvonnetastic, complete genome	28505-28536	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MH020241	Gordonia phage Fenry, complete genome	14259-14290	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	MH153808	Gordonia phage Petra, complete genome	14890-14921	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	KX557275	Gordonia phage CarolAnn, complete genome	14516-14547	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP022747	Sphingobium hydrophobicum strain C1 plasmid p1, complete sequence	180946-180977	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_016165	Rhodobacter phage RcapMu, complete genome	3892-3923	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	JF974309	Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces	58357-58388	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP013345	Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence	52037-52068	8	0.75
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP048608	Pseudomonas fluorescens strain DR133 plasmid unnamed, complete sequence	17127-17158	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP013855	Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence	81984-82015	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MN657146	Cryobacterium sp. strain ANT_H28B plasmid pA28BH2, complete sequence	27541-27572	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	148232-148263	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_006911	Streptomyces sp. F11 plasmid pFP11, complete sequence	14360-14391	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	585330-585361	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	KY087992	Mycobacterium phage Mitti, complete genome	54562-54593	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP012575	Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence	7760-7791	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	CP048046	Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence	7320-7351	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP048050	Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence	94213-94244	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP048048	Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence	9625-9656	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	1163829-1163860	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1020971-1021002	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_HG938354	Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence	970432-970463	8	0.75
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP021084	Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence	112455-112486	8	0.75
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	MK494119	Mycobacterium Phage Niklas, complete genome	30633-30665	8	0.758
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	MK310138	Mycobacterium phage Shaobing, complete genome	30630-30662	8	0.758
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	MF185722	Mycobacterium phage Peanam, complete genome	30630-30662	8	0.758
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	MN693323	Marine virus AFVG_25M87, complete genome	11504-11536	8	0.758
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1639653-1639685	8	0.758
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	NC_031230	Gordonia phage Yvonnetastic, complete genome	28504-28536	8	0.758
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MH020241	Gordonia phage Fenry, complete genome	14258-14290	8	0.758
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	MH153808	Gordonia phage Petra, complete genome	14889-14921	8	0.758
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	KX557275	Gordonia phage CarolAnn, complete genome	14515-14547	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	MN657146	Cryobacterium sp. strain ANT_H28B plasmid pA28BH2, complete sequence	27540-27572	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NC_010510	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence	89758-89790	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	585329-585361	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_CP012575	Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence	7760-7792	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	CP048046	Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence	7320-7352	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_CP048050	Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence	94213-94245	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_CP048048	Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence	9624-9656	8	0.758
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	217471-217503	8	0.758
NC_017186_22	22.1|6441980|32|NC_017186|CRISPRCasFinder	6441980-6442011	32	NZ_CP053712	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence	15514-15545	8	0.75
NC_017186_22	22.1|6441980|32|NC_017186|CRISPRCasFinder	6441980-6442011	32	NZ_CP014581	Burkholderia sp. OLGA172 plasmid pOLGA2, complete sequence	50178-50209	8	0.75
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NC_016624	Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence	309152-309183	8	0.75
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP029356	Azospirillum sp. CFH 70021 plasmid unnamed1	480167-480198	8	0.75
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1019226-1019257	8	0.75
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP029363	Streptomyces globisporus strain TFH56 plasmid pTFSG2, complete sequence	21050-21081	8	0.75
NC_017186_26	26.6|8280108|34|NC_017186|CRT	8280108-8280141	34	NZ_LR594691	Variovorax sp. WDL1 plasmid 3	300744-300777	8	0.765
NC_017186_26	26.6|8280108|34|NC_017186|CRT	8280108-8280141	34	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	707886-707919	8	0.765
NC_017186_16	16.1|5356410|34|NC_017186|CRISPRCasFinder	5356410-5356443	34	NZ_CP040823	Paraoceanicella profunda strain D4M1 plasmid pD4M1E, complete sequence	72540-72573	9	0.735
NC_017186_19	19.2|6436868|31|NC_017186|CRISPRCasFinder	6436868-6436898	31	NZ_CP032324	Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence	424273-424303	9	0.71
NC_017186_19	19.3|6436928|32|NC_017186|CRISPRCasFinder	6436928-6436959	32	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	304170-304201	9	0.719
NC_017186_19	19.3|6436928|32|NC_017186|CRISPRCasFinder	6436928-6436959	32	NZ_AP022333	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence	211010-211041	9	0.719
NC_017186_19	19.3|6436928|32|NC_017186|CRISPRCasFinder	6436928-6436959	32	NC_022049	Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence	321813-321844	9	0.719
NC_017186_19	19.6|6437107|30|NC_017186|CRISPRCasFinder	6437107-6437136	30	MN317029	Aeromonas phage vB_AhyS-A18P4, complete genome	52663-52692	9	0.7
NC_017186_19	19.7|6437166|32|NC_017186|CRISPRCasFinder	6437166-6437197	32	NZ_CP042825	Rhizobium sp. WL3 plasmid unnamed2, complete sequence	275530-275561	9	0.719
NC_017186_19	19.8|6437227|32|NC_017186|CRISPRCasFinder	6437227-6437258	32	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	1419193-1419224	9	0.719
NC_017186_19	19.8|6437227|32|NC_017186|CRISPRCasFinder	6437227-6437258	32	NC_014838	Pantoea sp. At-9b plasmid pPAT9B01, complete sequence	12157-12188	9	0.719
NC_017186_19	19.10|6437349|32|NC_017186|CRISPRCasFinder	6437349-6437380	32	MT889391	Mycobacterium phage MiniMac, complete genome	41968-41999	9	0.719
NC_017186_19	19.11|6437410|32|NC_017186|CRISPRCasFinder	6437410-6437441	32	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	524746-524777	9	0.719
NC_017186_19	19.11|6437410|32|NC_017186|CRISPRCasFinder	6437410-6437441	32	NC_006362	Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence	33272-33303	9	0.719
NC_017186_19	19.11|6437410|32|NC_017186|CRISPRCasFinder	6437410-6437441	32	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	29244-29275	9	0.719
NC_017186_19	19.15|6437657|32|NC_017186|CRISPRCasFinder	6437657-6437688	32	NC_022877	Bacillus thuringiensis YBT-1518 plasmid pBMB0232, complete sequence	50725-50756	9	0.719
NC_017186_19	19.15|6437657|32|NC_017186|CRISPRCasFinder	6437657-6437688	32	NC_022877	Bacillus thuringiensis YBT-1518 plasmid pBMB0232, complete sequence	51663-51694	9	0.719
NC_017186_20	20.3|6438753|33|NC_017186|PILER-CR,CRT	6438753-6438785	33	MH067969	Arthrobacter sp. strain ANT_H2 plasmid pA2H2, complete sequence	22225-22257	9	0.727
NC_017186_20	20.5|6438693|32|NC_017186|CRISPRCasFinder	6438693-6438724	32	NC_012527	Deinococcus deserti VCD115 plasmid 1, complete sequence	203996-204027	9	0.719
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	MH067969	Arthrobacter sp. strain ANT_H2 plasmid pA2H2, complete sequence	22225-22256	9	0.719
NC_017186_20	20.6|6438754|32|NC_017186|CRISPRCasFinder	6438754-6438785	32	NZ_CP013125	Pseudomonas mendocina S5.2 plasmid pPME5, complete sequence	181278-181309	9	0.719
NC_017186_20	20.7|6438815|32|NC_017186|CRISPRCasFinder	6438815-6438846	32	NC_004808	Streptomyces rochei plasmid pSLA2-L DNA, complete sequence	33807-33838	9	0.719
NC_017186_20	20.7|6438815|32|NC_017186|CRISPRCasFinder	6438815-6438846	32	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	1345895-1345926	9	0.719
NC_017186_20	20.7|6438815|32|NC_017186|CRISPRCasFinder	6438815-6438846	32	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	1164628-1164659	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP028972	Aminobacter sp. MSH1 plasmid pUSP4, complete sequence	11689-11720	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1840739-1840770	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	751241-751272	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	801919-801950	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	873344-873375	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1463567-1463598	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1068132-1068163	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	629182-629213	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	790174-790205	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	235840-235871	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	877690-877721	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1200943-1200974	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	3407-3438	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	1600056-1600087	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	805407-805438	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	704739-704770	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	804008-804039	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	991106-991137	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	278317-278348	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	801212-801243	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1184077-1184108	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	877679-877710	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	576821-576852	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	991073-991104	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	991074-991105	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	771812-771843	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	991087-991118	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	771835-771866	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	991087-991118	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1160220-1160251	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	991076-991107	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	771835-771866	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	806553-806584	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	787246-787277	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	841480-841511	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	878362-878393	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	991076-991107	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	771835-771866	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	926320-926351	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	991072-991103	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	771835-771866	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	771835-771866	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	991087-991118	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1187026-1187057	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	991098-991129	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	991076-991107	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1187026-1187057	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1225918-1225949	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1445929-1445960	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	716183-716214	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	892227-892258	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	1537042-1537073	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1221090-1221121	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1822606-1822637	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	867194-867225	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	911920-911951	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	867194-867225	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	911920-911951	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	867194-867225	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	867198-867229	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	911920-911951	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	911920-911951	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	911920-911951	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1165602-1165633	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1273240-1273271	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	867194-867225	9	0.719
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	911922-911953	9	0.719
NC_017186_21	21.2|6441506|32|NC_017186|CRISPRCasFinder	6441506-6441537	32	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	421416-421447	9	0.719
NC_017186_21	21.2|6441506|32|NC_017186|CRISPRCasFinder	6441506-6441537	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	331074-331105	9	0.719
NC_017186_21	21.3|6441567|32|NC_017186|CRISPRCasFinder	6441567-6441598	32	MN855771	Siphoviridae sp. isolate 189, complete genome	24967-24998	9	0.719
NC_017186_21	21.3|6441567|32|NC_017186|CRISPRCasFinder	6441567-6441598	32	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	230890-230921	9	0.719
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_010721	Methylorubrum populi BJ001 plasmid pMPOP02, complete sequence	20571-20602	9	0.719
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_015974	Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence	93158-93189	9	0.719
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NZ_CP005085	Sphingobium sp. TKS plasmid pTK1, complete sequence	402258-402289	9	0.719
NC_017186_21	21.5|6441689|32|NC_017186|CRISPRCasFinder	6441689-6441720	32	NC_009621	Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence	844108-844139	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP012185	Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence	574370-574401	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP025552	Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence	24787-24818	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP012182	Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence	474164-474195	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP022567	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK03, complete sequence	198319-198350	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MK224497	Mycobacterium phage Henu3, complete genome	3365-3396	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	KJ944841	Mycobacterium phage Cheetobro, complete genome	53842-53873	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MN945904	Mycobacterium phage Eponine, complete genome	55268-55299	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	AP018469	Mycobacterium phage Y10 DNA, complete genome, note: sample1	54590-54621	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MF140402	Mycobacterium phage Chancellor, complete genome	54288-54319	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	AP018470	Mycobacterium phage Y2 DNA, complete genome	54590-54621	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	KT361920	Mycobacterium phage Slarp, complete genome	53845-53876	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MT310882	Mycobacterium phage JF1, complete genome	54590-54621	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	AP018471	Mycobacterium phage Y10 DNA, complete genome, note: sample2	54590-54621	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MH051258	Mycobacterium phage SamScheppers, complete genome	54942-54973	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MF140435	Mycobacterium phage Wintermute, complete genome	54646-54677	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_027365	Mycobacterium virus Fionnbarth, complete genome	54666-54697	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_011892	Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence	197281-197312	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_047992	Microbacterium phage Zeta1847, complete genome	33287-33318	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP013538	Rhizobium phaseoli strain R630 plasmid pRphaR630a, complete sequence	55093-55124	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	426291-426322	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP034999	Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence	227938-227969	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP050090	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b4, complete sequence	111522-111553	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MK433264	Gordonia phage Tiamoceli, complete genome	53878-53909	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MT952843	Gordonia phage Twonlo, complete genome	54579-54610	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	MK977704	Gordonia Terrae phage RoadKill, complete genome	53988-54019	9	0.719
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	KR053200	Gordonia phage GTE6, complete genome	55232-55263	9	0.719
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	1451013-1451045	9	0.727
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	NC_016165	Rhodobacter phage RcapMu, complete genome	3892-3924	9	0.727
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	JF974309	Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces	58357-58389	9	0.727
NC_017186_21	21.11|6441688|33|NC_017186|CRT	6441688-6441720	33	NZ_CP022747	Sphingobium hydrophobicum strain C1 plasmid p1, complete sequence	180945-180977	9	0.727
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NC_006911	Streptomyces sp. F11 plasmid pFP11, complete sequence	14360-14392	9	0.727
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	1163828-1163860	9	0.727
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1020970-1021002	9	0.727
NC_017186_22	22.1|6441980|32|NC_017186|CRISPRCasFinder	6441980-6442011	32	NZ_CP014169	Sphingomonas panacis strain DCY99 plasmid unnamed, complete sequence	302055-302086	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	58941-58972	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP054620	Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence	378844-378875	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP013531	Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence	646255-646286	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP013584	Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence	646255-646286	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5121083-5121114	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	659921-659952	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	210763-210794	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP021127	Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence	382552-382583	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	451127-451158	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	514146-514177	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	431335-431366	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	688028-688059	9	0.719
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_LR594676	Variovorax sp. PBS-H4 plasmid 2	111008-111039	9	0.719
NC_017186_26	26.6|8280108|34|NC_017186|CRT	8280108-8280141	34	NC_013859	Azospirillum sp. B510 plasmid pAB510e, complete sequence	239822-239855	9	0.735
NC_017186_26	26.6|8280108|34|NC_017186|CRT	8280108-8280141	34	MN693688	Marine virus AFVG_250M167, complete genome	32043-32076	9	0.735
NC_017186_19	19.3|6436928|32|NC_017186|CRISPRCasFinder	6436928-6436959	32	NZ_CP031947	Ruegeria sp. AD91A plasmid unnamed1, complete sequence	415392-415423	10	0.688
NC_017186_19	19.8|6437227|32|NC_017186|CRISPRCasFinder	6437227-6437258	32	NZ_CP022370	Bosea sp. AS-1 plasmid unnamed1, complete sequence	5648-5679	10	0.688
NC_017186_19	19.20|6436988|34|NC_017186|CRT	6436988-6437021	34	NZ_CP020812	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed3, complete sequence	60762-60795	10	0.706
NC_017186_19	19.23|6437165|37|NC_017186|CRT	6437165-6437201	37	MH834621	Arthrobacter phage Nandita, complete genome	39362-39398	10	0.73
NC_017186_19	19.23|6437165|37|NC_017186|CRT	6437165-6437201	37	MH834627	Arthrobacter phage Ryan, complete genome	39915-39951	10	0.73
NC_017186_20	20.5|6438693|32|NC_017186|CRISPRCasFinder	6438693-6438724	32	NZ_CP017304	Rhodococcus sp. YL-1 plasmid pYLL2 sequence	28438-28469	10	0.688
NC_017186_20	20.5|6438693|32|NC_017186|CRISPRCasFinder	6438693-6438724	32	NC_005073	Rhodococcus erythropolis linear plasmid pBD2, complete sequence	28054-28085	10	0.688
NC_017186_20	20.8|6438814|33|NC_017186|CRT	6438814-6438846	33	NC_004808	Streptomyces rochei plasmid pSLA2-L DNA, complete sequence	33807-33839	10	0.697
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	KY945355	Mycobacterium phage Shandong1, complete genome	30384-30415	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP031117	Rubrobacter indicoceani strain SCSIO 08198 plasmid unnamed2, complete sequence	3531-3562	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP020740	[Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence	130591-130622	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NC_017324	Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence	1503231-1503262	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	315701-315732	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	859068-859099	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	213567-213598	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	192124-192155	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	442348-442379	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	CP016643	Mycobacterium sp. djl-10 plasmid djl-10_3, complete sequence	13154-13185	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP021794	Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence	1096817-1096848	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	183068-183099	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	203845-203876	10	0.688
NC_017186_21	21.4|6441628|32|NC_017186|CRISPRCasFinder	6441628-6441659	32	CP000663	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence	157233-157264	10	0.688
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP013381	Burkholderia sp. Bp5365 strain MSMB43 plasmid pMSMB43, complete sequence	285326-285357	10	0.688
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_011143	Phenylobacterium zucineum HLK1 plasmid, complete sequence	259683-259714	10	0.688
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	615987-616018	10	0.688
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP009547	Burkholderia sp. 2002721687 plasmid pBTU, complete sequence	137646-137677	10	0.688
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	3407-3439	10	0.697
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	1600056-1600088	10	0.697
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	576820-576852	10	0.697
NC_017186_21	21.7|6441444|33|NC_017186|CRT	6441444-6441476	33	KY945355	Mycobacterium phage Shandong1, complete genome	30384-30416	10	0.697
NC_017186_21	21.9|6441566|33|NC_017186|CRT	6441566-6441598	33	MN855771	Siphoviridae sp. isolate 189, complete genome	24966-24998	10	0.697
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NZ_CP022567	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK03, complete sequence	198318-198350	10	0.697
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NC_011892	Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence	197281-197313	10	0.697
NC_017186_21	21.12|6441749|33|NC_017186|CRT	6441749-6441781	33	NC_047992	Microbacterium phage Zeta1847, complete genome	33287-33319	10	0.697
NC_017186_22	22.1|6441980|32|NC_017186|CRISPRCasFinder	6441980-6442011	32	MH992209	Apis mellifera associated microvirus 17 isolate INH_SP_257, complete genome	4144-4175	10	0.688
NC_017186_22	22.2|6442041|32|NC_017186|CRISPRCasFinder	6442041-6442072	32	NZ_CP032827	Sphingomonas sp. YZ-8 plasmid unnamed2, complete sequence	21342-21373	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NC_015951	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence	253282-253313	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP016084	Streptomyces sp. SAT1 plasmid unnamed4, complete sequence	8076-8107	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	619909-619940	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP024427	Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence	4076-4107	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP039425	Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence	31316-31347	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP020443	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence	128521-128552	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NZ_CP039430	Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence	31316-31347	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	MN062714	Microbacterium Phage DirtyBubble, complete genome	24063-24094	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	MT024860	Microbacterium phage Stromboli, complete genome	24433-24464	10	0.688
NC_017186_22	22.4|6442162|32|NC_017186|CRISPRCasFinder	6442162-6442193	32	NC_016435	Gordonia phage GRU1, complete genome	37874-37905	10	0.688
NC_017186_21	21.1|6441445|32|NC_017186|CRISPRCasFinder	6441445-6441476	32	MK305889	Gordonia phage Mutzi, complete genome	38735-38766	11	0.656
NC_017186_21	21.2|6441506|32|NC_017186|CRISPRCasFinder	6441506-6441537	32	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	410572-410603	11	0.656
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	313454-313485	11	0.656
NC_017186_21	21.6|6441750|32|NC_017186|CRISPRCasFinder	6441750-6441781	32	KX815338	Streptomyces phage Joe, complete genome	37471-37502	11	0.656
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NC_017327	Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence	301211-301239	12	0.586
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	172212-172240	12	0.586
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP021801	Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence	69801-69829	12	0.586
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	1292917-1292945	12	0.586
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	51523-51551	12	0.586
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	84433-84461	12	0.586
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP019483	Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence	192563-192591	12	0.586
NC_017186_10	10.1|2899133|29|NC_017186|CRISPRCasFinder	2899133-2899161	29	NZ_CP019486	Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence	156447-156475	12	0.586

1. spacer 1.1|70655|26|NC_017186|CRISPRCasFinder matches to MN693271 (Marine virus AFVG_25M119, complete genome) position: , mismatch: 3, identity: 0.885

cggctcggggcgaagccctggaggtc	CRISPR spacer
gcgctcggggcgaagccctggcggtc	Protospacer
  ******************* ****

2. spacer 5.2|1356941|25|NC_017186|CRT matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.88

cgcgatgggcgagcgatgctcgata	CRISPR spacer
cgcaatgggcgagcgatgcgcgatt	Protospacer
***.*************** **** 

3. spacer 5.3|1356984|24|NC_017186|CRT matches to MH825706 (Streptomyces phage Microdon, complete genome) position: , mismatch: 3, identity: 0.875

catcgcggcgcacaacgaccggcg	CRISPR spacer
gatcgcggcgcacaaggaccggct	Protospacer
 ************** ******* 

4. spacer 5.3|1356984|24|NC_017186|CRT matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 3, identity: 0.875

catcgcggcgcacaacgaccggcg	CRISPR spacer
catcgcggcgctcaacgacctgcc	Protospacer
*********** ******** ** 

5. spacer 5.2|1356941|25|NC_017186|CRT matches to MN035621 (Leviviridae sp. isolate H1_Bulk_29_scaffold_509 RNA-dependent RNA polymerase (H1Bulk29509_000001) gene, partial cds; hypothetical protein (H1Bulk29509_000002) and hypothetical protein (H1Bulk29509_000003) genes, complete cds; and hypothetical protein (H1Bulk29509_000004) gene, partial cds) position: , mismatch: 4, identity: 0.84

cgcgatgggcgagcgatgctcgata	CRISPR spacer
cgcgaaaggcgagcgatgctcgaat	Protospacer
***** .****************  

6. spacer 5.2|1356941|25|NC_017186|CRT matches to MN034612 (Leviviridae sp. isolate H4_Bulk_48_scaffold_2658 sequence) position: , mismatch: 4, identity: 0.84

cgcgatgggcgagcgatgctcgata	CRISPR spacer
cgcgagaggcgagcgatgctcgagt	Protospacer
***** .****************  

7. spacer 5.2|1356941|25|NC_017186|CRT matches to MN034028 (Leviviridae sp. isolate H2_Rhizo_Litter_49_scaffold_1266 hypothetical protein (H2RhizoLitter491266_000001) gene, partial cds; hypothetical protein (H2RhizoLitter491266_000002) and hypothetical protein (H2RhizoLitter491266_000003) genes, complete cds; and RNA-dependent RNA polymerase (H2RhizoLitter491266_000004) gene, partial cds) position: , mismatch: 4, identity: 0.84

cgcgatgggcgagcgatgctcgata	CRISPR spacer
cgcgaaaggcgagcgatgctcgaat	Protospacer
***** .****************  

8. spacer 8.13|2088351|27|NC_017186|PILER-CR matches to NZ_KY362371 (Pseudomonas syringae pv. syringae strain UMAF1029 plasmid pPs1029, complete sequence) position: , mismatch: 4, identity: 0.852

-tggccgtgtcccgatgttcgcccgcgc	CRISPR spacer
ggggacat-tcccgatgttcgcccgcgc	Protospacer
  ** *.* *******************

9. spacer 8.13|2088351|27|NC_017186|PILER-CR matches to NZ_KY362370 (Pseudomonas syringae pv. syringae strain UMAF0158 plasmid pPs0158, complete sequence) position: , mismatch: 4, identity: 0.852

-tggccgtgtcccgatgttcgcccgcgc	CRISPR spacer
ggggacat-tcccgatgttcgcccgcgc	Protospacer
  ** *.* *******************

10. spacer 8.13|2088351|27|NC_017186|PILER-CR matches to NZ_CP005971 (Pseudomonas syringae UMAF0158 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.852

-tggccgtgtcccgatgttcgcccgcgc	CRISPR spacer
ggggacat-tcccgatgttcgcccgcgc	Protospacer
  ** *.* *******************

11. spacer 8.14|2088417|26|NC_017186|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.846

ccgatgcccacccagccgaccgcgtg	CRISPR spacer
gcgatgcccaccgagccgaccgcgaa	Protospacer
 *********** *********** .

12. spacer 8.14|2088417|26|NC_017186|PILER-CR matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 4, identity: 0.846

ccgatgcccacccagccgaccgcgtg	CRISPR spacer
tctatgccgacccagccgaccgcgag	Protospacer
.* ***** *************** *

13. spacer 8.14|2088417|26|NC_017186|PILER-CR matches to NZ_CP021082 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI1, complete sequence) position: , mismatch: 4, identity: 0.846

ccgatgcccacccagccgaccgcgtg	CRISPR spacer
gcgatgcccacccagccgaaagcggg	Protospacer
 ******************  *** *

14. spacer 5.3|1356984|24|NC_017186|CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 5, identity: 0.792

catcgcggcgcacaacgaccggcg	CRISPR spacer
gatcgcggcgcacaacgacctcgc	Protospacer
 *******************    

15. spacer 8.14|2088417|26|NC_017186|PILER-CR matches to NZ_CP020372 (Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence) position: , mismatch: 5, identity: 0.808

ccgatgcccacccagccgaccgcgtg	CRISPR spacer
gcgatggccacccagccgtccgcgcc	Protospacer
 ***** *********** *****. 

16. spacer 8.14|2088417|26|NC_017186|PILER-CR matches to NC_011143 (Phenylobacterium zucineum HLK1 plasmid, complete sequence) position: , mismatch: 5, identity: 0.808

ccgatgcccacccagccgaccgcgtg	CRISPR spacer
tcgatgaccagccagccgaccgcgat	Protospacer
.***** *** *************  

17. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP041018 (Sphingobium fuliginis ATCC 27551 plasmid pSF1, complete sequence) position: , mismatch: 5, identity: 0.828

gtccgatcgcccgggcgctcagcggtgcc-	CRISPR spacer
gagcgatcgcccgagcgctcagc-gtgcgg	Protospacer
*  **********.********* ****  

18. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 5, identity: 0.828

--gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
cggcccg--tgcccgggcgctcagcagtgcc	Protospacer
  *.***  .***************.*****

19. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP033227 (Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence) position: , mismatch: 5, identity: 0.828

gtccgatcgcccgggcgctcagcggtgcc-	CRISPR spacer
gagcgatcgcccgagcgctcagc-gtgcgg	Protospacer
*  **********.********* ****  

20. spacer 20.4|6438632|32|NC_017186|CRISPRCasFinder matches to NZ_CP027859 (Streptomyces clavuligerus strain ATCC 27064 plasmid pCLA1, complete sequence) position: , mismatch: 5, identity: 0.844

-ggagcactcgcatgacgaccacggagccggcg	CRISPR spacer
tggagc-cgcgcaggacgaccacggaaccggcc	Protospacer
 ***** * **** ************.***** 

21. spacer 20.4|6438632|32|NC_017186|CRISPRCasFinder matches to NZ_CP032054 (Streptomyces clavuligerus strain F1D-5 plasmid pSCL1, complete sequence) position: , mismatch: 5, identity: 0.844

-ggagcactcgcatgacgaccacggagccggcg	CRISPR spacer
tggagc-cgcgcaggacgaccacggaaccggcc	Protospacer
 ***** * **** ************.***** 

22. spacer 20.4|6438632|32|NC_017186|CRISPRCasFinder matches to NZ_CP016560 (Streptomyces clavuligerus strain F613-1 plasmid pSCL4, complete sequence) position: , mismatch: 5, identity: 0.844

-ggagcactcgcatgacgaccacggagccggcg	CRISPR spacer
tggagc-cgcgcaggacgaccacggaaccggcc	Protospacer
 ***** * **** ************.***** 

23. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 5, identity: 0.828

--acaaccggggcttcgccccgagccggggg	CRISPR spacer
cgacga--ggggcatcgccccgagccggcgg	Protospacer
  **.*  ***** ************** **

24. spacer 3.1|763149|30|NC_017186|CRISPRCasFinder matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 6, identity: 0.8

gaggaggctcccgctgccgaggaggccaag	CRISPR spacer
gcggaagctcccgctgccgaggacgctccg	Protospacer
* ***.***************** **.  *

25. spacer 3.1|763149|30|NC_017186|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.8

gaggaggctcccgctgccgaggaggccaag	CRISPR spacer
gccgcgactcccgctgccgcggaggccgag	Protospacer
*  * *.************ *******.**

26. spacer 8.14|2088417|26|NC_017186|PILER-CR matches to NC_021911 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1f, complete sequence) position: , mismatch: 6, identity: 0.769

ccgatgcccacccagccgaccgcgtg	CRISPR spacer
atcatgcccacccagccgagcgcgcc	Protospacer
 . **************** ****. 

27. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP047174 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gtccgagcgcccgggccctcagcgcgaac	Protospacer
****** ********* *******  . *

28. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to NZ_CP032686 (Rhizobium sp. CCGE531 plasmid pRCCGE531c, complete sequence) position: , mismatch: 6, identity: 0.8

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gcagttacgcggatgtcgtcgtcgttgggg	Protospacer
*. **   ****.*****************

29. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to NZ_CP032691 (Rhizobium sp. CCGE532 plasmid pRCCGE532c, complete sequence) position: , mismatch: 6, identity: 0.8

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gcagttacgcggatgtcgtcgtcgttgggg	Protospacer
*. **   ****.*****************

30. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to NZ_CP045331 (Labrenzia sp. THAF191b plasmid pTHAF191b_c, complete sequence) position: , mismatch: 6, identity: 0.8

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gtcgtgtagcggctgtcttcgtcggccgga	Protospacer
************ **** ****** . **.

31. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to NZ_CP045347 (Labrenzia sp. THAF187b plasmid pTHAF187b_c, complete sequence) position: , mismatch: 6, identity: 0.8

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gtcgtgtagcggctgtcttcgtcggccgga	Protospacer
************ **** ****** . **.

32. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to NZ_CP045336 (Labrenzia sp. THAF191a plasmid pTHAF191a_c, complete sequence) position: , mismatch: 6, identity: 0.8

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gtcgtgtagcggctgtcttcgtcggccgga	Protospacer
************ **** ****** . **.

33. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to NZ_CP045382 (Labrenzia sp. THAF35 plasmid pTHAF35_b, complete sequence) position: , mismatch: 6, identity: 0.8

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gtcgtgtagcggctgtcttcgtcggccgga	Protospacer
************ **** ****** . **.

34. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

35. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013589 (Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

36. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

37. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

38. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

39. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013546 (Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

40. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

41. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 6, identity: 0.793

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acgtcgaacgacacgtcggacagcgcttt	Protospacer
* *  ** *****************.**.

42. spacer 19.6|6437107|30|NC_017186|CRISPRCasFinder matches to NZ_CP032326 (Azospirillum brasilense strain MTCC4035 plasmid p5, complete sequence) position: , mismatch: 6, identity: 0.8

caggccgactacgagaagcagagcccgcag	CRISPR spacer
tatgccgactacgagaagctgagcaagctg	Protospacer
.* **************** ****  ** *

43. spacer 19.7|6437166|32|NC_017186|CRISPRCasFinder matches to MH834621 (Arthrobacter phage Nandita, complete genome) position: , mismatch: 6, identity: 0.812

atcccgcagtagcgacaggtgtcgccgtcgcg	CRISPR spacer
ttgaggcagtagcggcaggagtcgccgtcgcg	Protospacer
 *   *********.**** ************

44. spacer 19.7|6437166|32|NC_017186|CRISPRCasFinder matches to MH834627 (Arthrobacter phage Ryan, complete genome) position: , mismatch: 6, identity: 0.812

atcccgcagtagcgacaggtgtcgccgtcgcg	CRISPR spacer
ttgaggcagtagcggcaggagtcgccgtcgcg	Protospacer
 *   *********.**** ************

45. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NC_011892 (Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence) position: , mismatch: 6, identity: 0.812

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
aacgcggcggtggcctgcggatcctgggcgtg	Protospacer
*  *.************* *** ******** 

46. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP029211 (Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence) position: , mismatch: 6, identity: 0.812

acggt-ggcggtggcctgctgatactgggcgtc	CRISPR spacer
-cgctgggcggtggcctgctgatcccgggcaac	Protospacer
 ** * ***************** *.****. *

47. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 6, identity: 0.812

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
acgatgccgcgctcgaccaacaccgggatcgt	Protospacer
***************** ******  * ** .

48. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 6, identity: 0.812

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
acgatgccgcgctcgaccaacaccgggatcgt	Protospacer
***************** ******  * ** .

49. spacer 21.4|6441628|32|NC_017186|CRISPRCasFinder matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

gtgaagggcctctccccggccgggcagcggta	CRISPR spacer
gcgcttggcctctcccctgccgggcagcggca	Protospacer
*.*   *********** ************.*

50. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to MH576973 (Mycobacterium phage Bromden, complete genome) position: , mismatch: 6, identity: 0.812

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
accgtggccgactacttcggcctggacaaggt	Protospacer
   ********** *.************** *

51. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

acaaccggggcttcgccccgagccggggg	CRISPR spacer
gcgcccggggctccgccgcgagccgggga	Protospacer
.*. ********.**** **********.

52. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to NZ_CP026653 (Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

acaaccggggcttcgccccgagccggggg	CRISPR spacer
gcggcgggggcttcgtcccgcgccggggg	Protospacer
.*..* *********.**** ********

53. spacer 2.1|301050|29|NC_017186|CRISPRCasFinder matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 7, identity: 0.759

cggcgcggggcggagccccggatggcacg	CRISPR spacer
cggcgcggggcggggccccggcccgcttc	Protospacer
*************.******* . ** . 

54. spacer 3.1|763149|30|NC_017186|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.767

gaggaggctcccgctgccgaggaggccaag	CRISPR spacer
ccggaggcgcccgcggccgaggaggaagag	Protospacer
  ****** ***** **********  .**

55. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP011600 (Phytobacter ursingii strain CAV1151 plasmid pCAV1151-215, complete sequence) position: , mismatch: 7, identity: 0.759

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gtggtgatgcccggacgctcagcggtgcc	Protospacer
**   . .******.**************

56. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_AP018757 (Metakosakonia sp. MRY16-398 plasmid pMRY16-398_1, complete sequence) position: , mismatch: 7, identity: 0.759

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gtggtgatgcccggacgctcagcggtgcc	Protospacer
**   . .******.**************

57. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 7, identity: 0.759

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
cgacgattgcccgggcgatcagcggtcgc	Protospacer
   ****.********* ********  *

58. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.759

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
cgacgattgcccgggcgatcagcggtcgc	Protospacer
   ****.********* ********  *

59. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP021805 (Sinorhizobium meliloti strain T073 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.759

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
cgacgattgcccgggcgatcagcggtcgc	Protospacer
   ****.********* ********  *

60. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP021217 (Sinorhizobium meliloti RU11/001 plasmid pSymA, complete sequence) position: , mismatch: 7, identity: 0.759

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
cgacgattgcccgggcgatcagcggtcgc	Protospacer
   ****.********* ********  *

61. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to MH632120 (Mycobacterium phage Thonko, complete genome) position: , mismatch: 7, identity: 0.759

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
acccgatcgaccgggcgctcaacggcgtg	Protospacer
..******* ***********.***.*. 

62. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to AP018479 (Mycobacterium phage GS4E DNA, complete sequence) position: , mismatch: 7, identity: 0.767

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gagtagaagcgggtgtcgtcgtccttgtgg	Protospacer
*    * **************** *** **

63. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to MT310877 (Mycobacterium phage VA6, complete genome) position: , mismatch: 7, identity: 0.767

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gagtagaagcgggtgtcgtcgtccttgtgg	Protospacer
*    * **************** *** **

64. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to MT658804 (Mycobacterium phage BengiVuitton, complete genome) position: , mismatch: 7, identity: 0.767

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gagtagaagcgggtgtcgtcgtccttgtgg	Protospacer
*    * **************** *** **

65. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to NC_023597 (Mycobacterium phage 20ES, complete genome) position: , mismatch: 7, identity: 0.767

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gagtagaagcgggtgtcgtcgtccttgtgg	Protospacer
*    * **************** *** **

66. spacer 19.1|6436809|30|NC_017186|CRISPRCasFinder matches to MT310886 (Mycobacterium phage AN3, complete genome) position: , mismatch: 7, identity: 0.767

gtcgtgtagcgggtgtcgtcgtcgttgggg	CRISPR spacer
gagtagaagcgggtgtcgtcgtccttgtgg	Protospacer
*    * **************** *** **

67. spacer 19.3|6436928|32|NC_017186|CRISPRCasFinder matches to NC_015583 (Novosphingobium sp. PP1Y plasmid Mpl, complete sequence) position: , mismatch: 7, identity: 0.781

gcgccttcg-----tcccagctggccggctcgacgat	CRISPR spacer
-----ttcgtcacttcccagctggccggatcgatgat	Protospacer
     ****     ************** ****.***

68. spacer 19.4|6436989|29|NC_017186|CRISPRCasFinder matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 7, identity: 0.759

agggagatcgacacgtcggacagcgtttc	CRISPR spacer
acggggatcgaaacgtcggacagcgcaat	Protospacer
* **.****** *************.  .

69. spacer 19.10|6437349|32|NC_017186|CRISPRCasFinder matches to KY555145 (Caulobacter phage Ccr29, complete genome) position: , mismatch: 7, identity: 0.781

gtctcgaacgtcgtgggcgagacgacgtgctc	CRISPR spacer
ggttccagggtcatgggcgagacgacgtgatc	Protospacer
* .** *. ***.**************** **

70. spacer 19.10|6437349|32|NC_017186|CRISPRCasFinder matches to KY555143 (Caulobacter phage Ccr2, complete genome) position: , mismatch: 7, identity: 0.781

gtctcgaacgtcgtgggcgagacgacgtgctc	CRISPR spacer
ggttccagggtcatgggcgagacgacgtgatc	Protospacer
* .** *. ***.**************** **

71. spacer 19.10|6437349|32|NC_017186|CRISPRCasFinder matches to KY555142 (Caulobacter phage Ccr10, complete genome) position: , mismatch: 7, identity: 0.781

gtctcgaacgtcgtgggcgagacgacgtgctc	CRISPR spacer
ggttccagggtcatgggcgagacgacgtgatc	Protospacer
* .** *. ***.**************** **

72. spacer 20.3|6438753|33|NC_017186|PILER-CR,CRT matches to NC_011892 (Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence) position: , mismatch: 7, identity: 0.788

cacggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
aaacgcggcggtggcctgcggatcctgggcgtg	Protospacer
 *  *.************* *** ******** 

73. spacer 20.3|6438753|33|NC_017186|PILER-CR,CRT matches to NZ_CP029211 (Aquabacterium olei strain NBRC 110486 plasmid pTB101, complete sequence) position: , mismatch: 7, identity: 0.788

-cacggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
tcgctg-ggcggtggcctgctgatcccgggcaac	Protospacer
 *.* * ***************** *.****. *

74. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP040937 (Hymenobacter sp. DG01 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
acgctctgggtggcctgctcgtactgggcgta	Protospacer
*** *   *********** .********** 

75. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP028350 (Pantoea vagans strain PV989 plasmid pPV989-508, complete sequence) position: , mismatch: 7, identity: 0.781

acggtg-gcggtggcctgctgatactgggcgtc	CRISPR spacer
-cggtatttggcggcctgctgattctgggcgtg	Protospacer
 ****.  .**.*********** ******** 

76. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NC_014258 (Pantoea vagans C9-1 plasmid pPag3, complete sequence) position: , mismatch: 7, identity: 0.781

acggtg-gcggtggcctgctgatactgggcgtc	CRISPR spacer
-cggtatttggcggcctgctgattctgggcgtg	Protospacer
 ****.  .**.*********** ******** 

77. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP038854 (Pantoea vagans strain LMG 24199 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

acggtg-gcggtggcctgctgatactgggcgtc	CRISPR spacer
-cggtatttggcggcctgctgattctgggcgtg	Protospacer
 ****.  .**.*********** ******** 

78. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP006588 (Hymenobacter sp. APR13 plasmid pHA, complete sequence) position: , mismatch: 7, identity: 0.781

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
acgctctgggtggcctgctcgtactgggcgta	Protospacer
*** *   *********** .********** 

79. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP010410 (Xanthomonas sacchari strain R1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
atgtagccgccatcgacgaacacctcgtcgcc	Protospacer
*.*  *****  ****************. **

80. spacer 21.2|6441506|32|NC_017186|CRISPRCasFinder matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 7, identity: 0.781

tcggccagcacccggcggaggttccggatact	CRISPR spacer
ggggccagcgcccggcggaggttctggaccat	Protospacer
  *******.**************.***.  *

81. spacer 21.2|6441506|32|NC_017186|CRISPRCasFinder matches to NC_008441 (Streptomyces laurentii plasmid pSLS DNA, complete sequence) position: , mismatch: 7, identity: 0.781

tcggccagcacccggcggaggttccg-gatact	CRISPR spacer
gcgaccagcacccggcggatgttccacgacag-	Protospacer
 **.*************** *****. **.*  

82. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK919470 (Gordonia phage Mellie, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

83. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MN234179 (Gordonia phage Pipp, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

84. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MN010762 (Gordonia phage MintFen, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

85. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MT553336 (Gordonia phage BlingBling, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

86. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_031265 (Gordonia phage Guacamole, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

87. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MF919521 (Gordonia phage Lysidious, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

88. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MN369740 (Gordonia phage Delian, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

89. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK801724 (Gordonia phage PhrostedPhlake, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

90. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MH576969 (Gordonia phage Zarbodnamra, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

91. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK864263 (Gordonia phage Melba, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

92. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MN062704 (Gordonia phage JuJu, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

93. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK878896 (Gordonia phage Begonia, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

94. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK501729 (Gordonia phage Walrus, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

95. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MT723942 (Gordonia phage Archis, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

96. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK967389 (Gordonia phage JasperJr, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

97. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK501730 (Gordonia phage Barco, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

98. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to KU963251 (Gordonia phage UmaThurman, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

99. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to KX557274 (Gordonia phage CaptainKirk2, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

100. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MT723936 (Gordonia phage Hitter, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

101. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_031237 (Gordonia phage Obliviate, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

102. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_030921 (Gordonia phage Utz, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

103. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MN585963 (Gordonia phage Wocket, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gagaccggcaagcccgaggcggtcctcaactg	Protospacer
 * ******************.******  ..

104. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cacaccggcgagcccgatgcgatcccggcggt	Protospacer
*********.******* *******. .**  

105. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MK977705 (Gordonia Phage Mollymur, complete genome) position: , mismatch: 7, identity: 0.781

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
acctccggcaagcccgaggcggtcttcaccaa	Protospacer
  * *****************.**.****  *

106. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP023450 (Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

cacacc-ggcaagcccgaggcgatcctcacgca	CRISPR spacer
-actccgggcgagcccgaggcgatcttcactgc	Protospacer
 ** ** ***.**************.****   

107. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP010956 (Sphingobium sp. YBL2 plasmid 2pYBL2-2, complete sequence) position: , mismatch: 7, identity: 0.781

cacacc-ggcaagcccgaggcgatcctcacgca	CRISPR spacer
-actccgggcgagcccgaggcgatcttcactgc	Protospacer
 ** ** ***.**************.****   

108. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_015595 (Sphingobium chlorophenolicum L-1 plasmid pSPHCH01, complete sequence) position: , mismatch: 7, identity: 0.781

cacacc-ggcaagcccgaggcgatcctcacgca	CRISPR spacer
-actccgggcgagcccgaggcgatcttcactgc	Protospacer
 ** ** ***.**************.****   

109. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP018225 (Tardibacter chloracetimidivorans strain JJ-A5 plasmid pHSL4, complete sequence) position: , mismatch: 7, identity: 0.781

cacacc-ggcaagcccgaggcgatcctcacgca	CRISPR spacer
-actccgggcgagcccgaggcgatcttcactgc	Protospacer
 ** ** ***.**************.****   

110. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP013265 (Sphingobium baderi strain DE-13 plasmid pDE1, complete sequence) position: , mismatch: 7, identity: 0.781

cacacc-ggcaagcccgaggcgatcctcacgca	CRISPR spacer
-actccgggcgagcccgaggcgatcttcactgc	Protospacer
 ** ** ***.**************.****   

111. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 7, identity: 0.781

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aacacgacggcgagcgcgtcgtcgcgctgttc	Protospacer
.**************  *********.* .*.

112. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gctcctacggcgtgccggccgtcgcgttcctg	Protospacer
* . * ****** *****.************ 

113. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP047175 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

gacacga---cggcgagccggtcgtcgcgttcctt	CRISPR spacer
---tcgagctcggcgagccgggcgtcgcgctcctc	Protospacer
    ***   *********** *******.****.

114. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 7, identity: 0.781

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gacacgacgtcgagccggttgtcgacatgctc	Protospacer
********* *********.****   * **.

115. spacer 21.7|6441444|33|NC_017186|CRT matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 7, identity: 0.788

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gacgatgccgcgctcgaccaacaccgggatcgt	Protospacer
 ***************** ******  * ** .

116. spacer 21.7|6441444|33|NC_017186|CRT matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 7, identity: 0.788

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gacgatgccgcgctcgaccaacaccgggatcgt	Protospacer
 ***************** ******  * ** .

117. spacer 21.8|6441505|33|NC_017186|CRT matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 7, identity: 0.788

ctcggccagcacccggcggaggttccggatact	CRISPR spacer
cggggccagcgcccggcggaggttctggaccat	Protospacer
*  *******.**************.***.  *

118. spacer 21.8|6441505|33|NC_017186|CRT matches to NC_008441 (Streptomyces laurentii plasmid pSLS DNA, complete sequence) position: , mismatch: 7, identity: 0.788

ctcggccagcacccggcggaggttccg-gatact	CRISPR spacer
cgcgaccagcacccggcggatgttccacgacag-	Protospacer
* **.*************** *****. **.*  

119. spacer 21.10|6441627|33|NC_017186|CRT matches to NZ_CP044079 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

ggtgaagggcctctccccggccgggcagcggta	CRISPR spacer
cgcgcttggcctctcccctgccgggcagcggca	Protospacer
 *.*   *********** ************.*

120. spacer 21.11|6441688|33|NC_017186|CRT matches to MK919470 (Gordonia phage Mellie, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

121. spacer 21.11|6441688|33|NC_017186|CRT matches to MN234179 (Gordonia phage Pipp, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

122. spacer 21.11|6441688|33|NC_017186|CRT matches to MN010762 (Gordonia phage MintFen, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

123. spacer 21.11|6441688|33|NC_017186|CRT matches to MT553336 (Gordonia phage BlingBling, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

124. spacer 21.11|6441688|33|NC_017186|CRT matches to NC_031265 (Gordonia phage Guacamole, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

125. spacer 21.11|6441688|33|NC_017186|CRT matches to MF919521 (Gordonia phage Lysidious, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

126. spacer 21.11|6441688|33|NC_017186|CRT matches to MN369740 (Gordonia phage Delian, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

127. spacer 21.11|6441688|33|NC_017186|CRT matches to MK801724 (Gordonia phage PhrostedPhlake, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

128. spacer 21.11|6441688|33|NC_017186|CRT matches to MH576969 (Gordonia phage Zarbodnamra, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

129. spacer 21.11|6441688|33|NC_017186|CRT matches to MK864263 (Gordonia phage Melba, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

130. spacer 21.11|6441688|33|NC_017186|CRT matches to MN062704 (Gordonia phage JuJu, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

131. spacer 21.11|6441688|33|NC_017186|CRT matches to MK878896 (Gordonia phage Begonia, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

132. spacer 21.11|6441688|33|NC_017186|CRT matches to MK501729 (Gordonia phage Walrus, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

133. spacer 21.11|6441688|33|NC_017186|CRT matches to MT723942 (Gordonia phage Archis, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

134. spacer 21.11|6441688|33|NC_017186|CRT matches to MK967389 (Gordonia phage JasperJr, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

135. spacer 21.11|6441688|33|NC_017186|CRT matches to MK501730 (Gordonia phage Barco, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

136. spacer 21.11|6441688|33|NC_017186|CRT matches to KU963251 (Gordonia phage UmaThurman, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

137. spacer 21.11|6441688|33|NC_017186|CRT matches to KX557274 (Gordonia phage CaptainKirk2, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

138. spacer 21.11|6441688|33|NC_017186|CRT matches to MT723936 (Gordonia phage Hitter, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

139. spacer 21.11|6441688|33|NC_017186|CRT matches to NC_031237 (Gordonia phage Obliviate, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

140. spacer 21.11|6441688|33|NC_017186|CRT matches to NC_030921 (Gordonia phage Utz, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

141. spacer 21.11|6441688|33|NC_017186|CRT matches to MN585963 (Gordonia phage Wocket, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgagaccggcaagcccgaggcggtcctcaactg	Protospacer
* * ******************.******  ..

142. spacer 21.11|6441688|33|NC_017186|CRT matches to MK977705 (Gordonia Phage Mollymur, complete genome) position: , mismatch: 7, identity: 0.788

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cacctccggcaagcccgaggcggtcttcaccaa	Protospacer
*  * *****************.**.****  *

143. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cgctcctacggcgtgccggccgtcgcgttcctg	Protospacer
** . * ****** *****.************ 

144. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_CP047175 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

cgacacga---cggcgagccggtcgtcgcgttcctt	CRISPR spacer
---ctcgagctcggcgagccgggcgtcgcgctcctc	Protospacer
   * ***   *********** *******.****.

145. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

146. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

147. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

148. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

149. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

150. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

151. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

152. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

153. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

154. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

155. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

156. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

157. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

158. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

159. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

160. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

161. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

162. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

163. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 7, identity: 0.781

acgaagtagatgcccgcgtgctggatggtgag--	CRISPR spacer
gcgaagtagagtcccgcgtgctgga--gcgatcc	Protospacer
.*********  *************  *.**   

164. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP035092 (Paracoccus denitrificans strain ATCC 19367 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.781

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
ggggtggacgacttccccggcctggatctgcc	Protospacer
 ****** ********.*********.  **.

165. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NC_008688 (Paracoccus denitrificans PD1222 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.781

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
ggggtggacgacttccccggcctggatctgcc	Protospacer
 ****** ********.*********.  **.

166. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_LR134468 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 26, complete sequence) position: , mismatch: 7, identity: 0.781

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
aagctggccgacctcgtcggcctggacacggt	Protospacer
 .* ********.** ************ * *

167. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP023000 (Rhizobium sp. 11515TR strain 10195 plasmid p11515TR-B, complete sequence) position: , mismatch: 7, identity: 0.781

tgggtggccgacttcctcggcctggacaagct---	CRISPR spacer
tggcttgccgacttcctcggcct---ccatcttgg	Protospacer
*** * *****************   * * **   

168. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to NC_023285 (Streptomyces sp. F8 plasmid pFRL5, complete sequence) position: , mismatch: 7, identity: 0.759

acaaccggggcttcgccccgagccggggg	CRISPR spacer
ggcactggggcttcgccccgagacgggca	Protospacer
.  **.**************** **** .

169. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to NC_011962 (Rhodobacter sphaeroides KD131 plasmid pRSKD131A, complete sequence) position: , mismatch: 7, identity: 0.759

acaaccggggcttcgccccgagccggggg	CRISPR spacer
ctatgcggggcttcgccccgaggcgcggc	Protospacer
 .*  ***************** ** ** 

170. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to NZ_CP020810 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

acaaccggggcttcgccccgagccggggg	CRISPR spacer
acaaccgtggctgcgccccgagcatcgcc	Protospacer
******* **** **********   *  

171. spacer 25.1|6961022|29|NC_017186|CRISPRCasFinder matches to NZ_CP020041 (Streptomyces sp. 3211 isolate 3 plasmid p3211-2, complete sequence) position: , mismatch: 7, identity: 0.759

acaaccggggcttcgccccgagccggggg	CRISPR spacer
cggaccggggcttcgccccgatcccgaag	Protospacer
  .****************** ** *..*

172. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 8, identity: 0.724

gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
cgacgatcgcccgggcgatcagcggacgg	Protospacer
   ************** *******    

173. spacer 19.2|6436868|31|NC_017186|CRISPRCasFinder matches to NZ_CP012899 (Burkholderia sp. CCGE1001 plasmid pCCGE1001a, complete sequence) position: , mismatch: 8, identity: 0.742

tgcccg---tggcggaacctgatcgtcaccaagc	CRISPR spacer
---acgaattggcggaacctgaacgtcagcaaag	Protospacer
    **   ************* ***** ***. 

174. spacer 19.2|6436868|31|NC_017186|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.742

tgcccgtggcggaacctgatcgtcaccaagc	CRISPR spacer
ggcccgtcgctgaacctgatcgtcctggaga	Protospacer
 ****** ** ************* . .** 

175. spacer 19.5|6437047|31|NC_017186|CRISPRCasFinder matches to NZ_CP013071 (Sphingobium indicum B90A plasmid pSRL1, complete sequence) position: , mismatch: 8, identity: 0.742

ggaagccggttgagcttcgcgccgcaccgtc	CRISPR spacer
gcctgccggttgatcatcgcgccgcactggg	Protospacer
*   ********* * ***********.*  

176. spacer 19.5|6437047|31|NC_017186|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

ggaagccggttgagcttcgcgccgcaccgtc	CRISPR spacer
ccagggtggctgagctgcgcgccgcaccgtt	Protospacer
  *.* .**.****** *************.

177. spacer 19.10|6437349|32|NC_017186|CRISPRCasFinder matches to NZ_CP024312 (Rhizobium sp. NXC24 plasmid pRspNXC24a, complete sequence) position: , mismatch: 8, identity: 0.75

gtctcgaacgtcgtgggcgagacgacgtgctc	CRISPR spacer
tcctctaatgtcgtgggcgagacgacgacgac	Protospacer
 .*** **.******************    *

178. spacer 19.11|6437410|32|NC_017186|CRISPRCasFinder matches to NC_006362 (Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence) position: , mismatch: 8, identity: 0.75

gacttcaagctgcgcctggtcaccctcggcgt	CRISPR spacer
cgctcgatgctgcacctggtcaacctcggcgc	Protospacer
 .**. * *****.******** ********.

179. spacer 19.11|6437410|32|NC_017186|CRISPRCasFinder matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 8, identity: 0.75

gacttcaagctgcgcctggtcaccctcggcgt	CRISPR spacer
ggcggtatcctgcgcctgggcaacctcggcgt	Protospacer
*.*  .*  ********** ** *********

180. spacer 19.11|6437410|32|NC_017186|CRISPRCasFinder matches to NZ_CP045303 (Azotobacter salinestris strain KACC 13899 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gacttcaagctgcgcctggtcaccctcggcgt	CRISPR spacer
tgccttgagcagcgcctggtcacccttggctt	Protospacer
 .*.*..*** ***************.*** *

181. spacer 20.3|6438753|33|NC_017186|PILER-CR,CRT matches to AF069529 (Bacteriophage HK97, complete genome) position: , mismatch: 8, identity: 0.758

cacggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
ctgcgtggcggtggcctgctgatagtcggagag	Protospacer
*   ******************** * ** *  

182. spacer 20.3|6438753|33|NC_017186|PILER-CR,CRT matches to NC_002167 (Enterobacteria phage HK97, complete genome) position: , mismatch: 8, identity: 0.758

cacggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
ctgcgtggcggtggcctgctgatagtcggagag	Protospacer
*   ******************** * ** *  

183. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to AF069529 (Bacteriophage HK97, complete genome) position: , mismatch: 8, identity: 0.75

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
tgcgtggcggtggcctgctgatagtcggagag	Protospacer
   ******************** * ** *  

184. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NC_002167 (Enterobacteria phage HK97, complete genome) position: , mismatch: 8, identity: 0.75

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
tgcgtggcggtggcctgctgatagtcggagag	Protospacer
   ******************** * ** *  

185. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
tggttggcgttggcctgctgatgctggcggcc	Protospacer
  * ***** ************.****  *.*

186. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 8, identity: 0.75

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
tggttggcgttggcctgctgatgctggcggcc	Protospacer
  * ***** ************.****  *.*

187. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP040824 (Paraoceanicella profunda strain D4M1 plasmid pD4M1F, complete sequence) position: , mismatch: 8, identity: 0.75

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
gcggtggcgctggcctgcggatacgcgccgct	Protospacer
.******** ******** *****  * **..

188. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MK494119 (Mycobacterium Phage Niklas, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
cagccgccgcgctcggcgaacacctcgttgag	Protospacer
  * .**********.*************   

189. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MK310138 (Mycobacterium phage Shaobing, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
cagccgccgcgctcggcgaacacctcgttgag	Protospacer
  * .**********.*************   

190. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MF185722 (Mycobacterium phage Peanam, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
cagccgccgcgctcggcgaacacctcgttgag	Protospacer
  * .**********.*************   

191. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gtgacgccgcgctcggcgaacacctcgcgggc	Protospacer
..**.**********.***********.   *

192. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gccgggctacgctcgaggaacacgtcgttccc	Protospacer
.* . **..******* ****** ********

193. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP048634 (Rhizobium oryzihabitans strain M15 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.75

acgatg-ccgcgctcgacgaacacctcgttccc	CRISPR spacer
-cgagatccgcgctcgacggacgcctcgttgtt	Protospacer
 *** . ************.**.******* ..

194. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP048638 (Rhizobium oryzihabitans strain M15 plasmid p6, complete sequence) position: , mismatch: 8, identity: 0.75

acgatg-ccgcgctcgacgaacacctcgttccc	CRISPR spacer
-cgagatccgcgctcgacggacgcctcgttgtt	Protospacer
 *** . ************.**.******* ..

195. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP048639 (Rhizobium oryzihabitans strain M15 plasmid p7, complete sequence) position: , mismatch: 8, identity: 0.75

acgatg-ccgcgctcgacgaacacctcgttccc	CRISPR spacer
-cgagatccgcgctcgacggacgcctcgttgtt	Protospacer
 *** . ************.**.******* ..

196. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 8, identity: 0.75

acgatgcc-gcgctcgacgaacacctcgttccc	CRISPR spacer
-ccttactggcgcgggacgaacacctcgttccg	Protospacer
 *  *.*. ****  ***************** 

197. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MN096355 (Mycobacterium phage Purky, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
aacacgtcgggctcgacgaacaccgcgttcgg	Protospacer
*  *.*.** ************** *****  

198. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MK016499 (Mycobacterium phage Mangethe, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
aacacgtcgggctcgacgaacaccgcgttcgg	Protospacer
*  *.*.** ************** *****  

199. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MK919480 (Mycobacterium phage Techage, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
aacacgtcgggctcgacgaacaccgcgttcgg	Protospacer
*  *.*.** ************** *****  

200. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MF919492 (Mycobacterium phage Arib1, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
aacacgtcgggctcgacgaacaccgcgttcgg	Protospacer
*  *.*.** ************** *****  

201. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NC_041969 (Mycobacterium phage Jebeks, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
aacacgtcgggctcgacgaacaccgcgttcgg	Protospacer
*  *.*.** ************** *****  

202. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NC_023552 (Mycobacterium phage Donovan, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
aacacgtcgggctcgacgaacaccgcgttcgg	Protospacer
*  *.*.** ************** *****  

203. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MN693323 (Marine virus AFVG_25M87, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc---	CRISPR spacer
acgatgcagcgctcgaggaaca---cggaccaggg	Protospacer
******* ******** *****   **  **    

204. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MF472894 (Mycobacterium phage Majeke, complete genome) position: , mismatch: 8, identity: 0.75

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
aacacgtcgggctcgacgaacaccgcgttcgg	Protospacer
*  *.*.** ************** *****  

205. spacer 21.2|6441506|32|NC_017186|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.75

tcggccagcacccggcggaggttccggatact--	CRISPR spacer
tcgggcagcacccggcggagctt--ggccgccgc	Protospacer
**** *************** **  ** ..*.  

206. spacer 21.2|6441506|32|NC_017186|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.75

tcggccagcacccggcggaggttccggatact--	CRISPR spacer
tcgggcagcacccggcggagctt--ggccgccgc	Protospacer
**** *************** **  ** ..*.  

207. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_031230 (Gordonia phage Yvonnetastic, complete genome) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
atgtccggcaagcccgaggcggtcttcaccaa	Protospacer
    *****************.**.****  *

208. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MH020241 (Gordonia phage Fenry, complete genome) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccgggaagcccgaggcggtcctcaactg	Protospacer
 * ***** ************.******  ..

209. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to MH153808 (Gordonia phage Petra, complete genome) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaactggcaagcccgaggcggtcctcaactg	Protospacer
 * **.***************.******  ..

210. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to KX557275 (Gordonia phage CarolAnn, complete genome) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaaccggcaagcccgaagcggtcctcaactg	Protospacer
 * **************.***.******  ..

211. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP022747 (Sphingobium hydrophobicum strain C1 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
ggcgacggcaagcccgaggctatcatcacaga	Protospacer
 .*. *************** *** ****. *

212. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_016165 (Rhodobacter phage RcapMu, complete genome) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
catctcgacaagcccgaagcgatcctcaccgc	Protospacer
**. .**.*********.***********   

213. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
catctcgacaagcccgaagcgatcctcaccgc	Protospacer
**. .**.*********.***********   

214. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP013345 (Sphingopyxis macrogoltabida strain 203N plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaaatctgcaagcccgaggcgatcgtcgcgac	Protospacer
 * *.* ***************** **.**  

215. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP048608 (Pseudomonas fluorescens strain DR133 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gacgccggcaaccccgaggcgatcgccaacaa	Protospacer
 **.******* ************ .**   *

216. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP013855 (Pseudonocardia sp. HH130630-07 plasmid pLS2-1, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cgcagcgcggcgagccgggcgtcgcgttcccc	Protospacer
 .**  .*********** ***********..

217. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MN657146 (Cryobacterium sp. strain ANT_H28B plasmid pA28BH2, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
accgcgacggcgagccggtcgccgcgatcggc	Protospacer
. *.*****************.**** **  .

218. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gacacgacggcgggccggtcgtccgccacccc	Protospacer
************.**********   . **..

219. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_006911 (Streptomyces sp. F11 plasmid pFP11, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cccgcgacggcgagccggtcaccgcgttcggc	Protospacer
  *.****************..*******  .

220. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
tgatcgccggcgagccggtcgtcgccttcatc	Protospacer
 .  ** ****************** *** *.

221. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to KY087992 (Mycobacterium phage Mitti, complete genome) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccccg	Protospacer
.. ******.**************** .**. 

222. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP012575 (Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
taacgggcggcgagccggtcggcgcgctcctg	Protospacer
 *   *.************** ****.**** 

223. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to CP048046 (Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
taacgggcggcgagccggtcggcgcgctcctg	Protospacer
 *   *.************** ****.**** 

224. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP048050 (Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
taacgggcggcgagccggtcggcgcgctcctg	Protospacer
 *   *.************** ****.**** 

225. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP048048 (Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
taacgggcggcgagccggtcggcgcgctcctg	Protospacer
 *   *.************** ****.**** 

226. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
accacgacgacgagcctgtcgtcgcggccgtg	Protospacer
. *******.****** ********* .* * 

227. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
accacgacgacgagcctgtcgtcgcggccgtg	Protospacer
. *******.****** ********* .* * 

228. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_HG938354 (Neorhizobium galegae bv. orientalis str. HAMBI 540 plasmid pHAMBI540a, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cgctcgacggcgagacgatcgtcgcgtcgcgt	Protospacer
 .* ********** **.*********. * *

229. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP021084 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence) position: , mismatch: 8, identity: 0.75

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gcagcaaaggccagccggtcgtcgtgttcctc	Protospacer
*  .*.* *** ************.******.

230. spacer 21.7|6441444|33|NC_017186|CRT matches to MK494119 (Mycobacterium Phage Niklas, complete genome) position: , mismatch: 8, identity: 0.758

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
ccagccgccgcgctcggcgaacacctcgttgag	Protospacer
*  * .**********.*************   

231. spacer 21.7|6441444|33|NC_017186|CRT matches to MK310138 (Mycobacterium phage Shaobing, complete genome) position: , mismatch: 8, identity: 0.758

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
ccagccgccgcgctcggcgaacacctcgttgag	Protospacer
*  * .**********.*************   

232. spacer 21.7|6441444|33|NC_017186|CRT matches to MF185722 (Mycobacterium phage Peanam, complete genome) position: , mismatch: 8, identity: 0.758

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
ccagccgccgcgctcggcgaacacctcgttgag	Protospacer
*  * .**********.*************   

233. spacer 21.7|6441444|33|NC_017186|CRT matches to MN693323 (Marine virus AFVG_25M87, complete genome) position: , mismatch: 8, identity: 0.758

cacgatgccgcgctcgacgaacacctcgttccc---	CRISPR spacer
cacgatgcagcgctcgaggaaca---cggaccaggg	Protospacer
******** ******** *****   **  **    

234. spacer 21.11|6441688|33|NC_017186|CRT matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.758

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gcacaccggcgagcccgatgcgatcccggcggt	Protospacer
 *********.******* *******. .**  

235. spacer 21.11|6441688|33|NC_017186|CRT matches to NC_031230 (Gordonia phage Yvonnetastic, complete genome) position: , mismatch: 8, identity: 0.758

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
catgtccggcaagcccgaggcggtcttcaccaa	Protospacer
*    *****************.**.****  *

236. spacer 21.11|6441688|33|NC_017186|CRT matches to MH020241 (Gordonia phage Fenry, complete genome) position: , mismatch: 8, identity: 0.758

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccgggaagcccgaggcggtcctcaactg	Protospacer
* * ***** ************.******  ..

237. spacer 21.11|6441688|33|NC_017186|CRT matches to MH153808 (Gordonia phage Petra, complete genome) position: , mismatch: 8, identity: 0.758

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaactggcaagcccgaggcggtcctcaactg	Protospacer
* * **.***************.******  ..

238. spacer 21.11|6441688|33|NC_017186|CRT matches to KX557275 (Gordonia phage CarolAnn, complete genome) position: , mismatch: 8, identity: 0.758

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
cgaaaccggcaagcccgaagcggtcctcaactg	Protospacer
* * **************.***.******  ..

239. spacer 21.12|6441749|33|NC_017186|CRT matches to MN657146 (Cryobacterium sp. strain ANT_H28B plasmid pA28BH2, complete sequence) position: , mismatch: 8, identity: 0.758

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
caccgcgacggcgagccggtcgccgcgatcggc	Protospacer
*. *.*****************.**** **  .

240. spacer 21.12|6441749|33|NC_017186|CRT matches to NC_010510 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD01, complete sequence) position: , mismatch: 8, identity: 0.758

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gaacacgacggcgagcgcgtcgtcgcgctgttc	Protospacer
 .**************  *********.* .*.

241. spacer 21.12|6441749|33|NC_017186|CRT matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 8, identity: 0.758

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
ctgatcgccggcgagccggtcgtcgccttcatc	Protospacer
* .  ** ****************** *** *.

242. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_CP012575 (Clavibacter michiganensis subsp. capsici strain PF008 plasmid pCM2, complete sequence) position: , mismatch: 8, identity: 0.758

-cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gtaacg-ggcggcgagccggtcggcgcgctcctg	Protospacer
 ..**. *.************** ****.**** 

243. spacer 21.12|6441749|33|NC_017186|CRT matches to CP048046 (Clavibacter michiganensis subsp. capsici strain 1207 plasmid pCM2_1207, complete sequence) position: , mismatch: 8, identity: 0.758

-cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gtaacg-ggcggcgagccggtcggcgcgctcctg	Protospacer
 ..**. *.************** ****.**** 

244. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_CP048050 (Clavibacter michiganensis subsp. capsici strain 1101 plasmid pCM2_1101, complete sequence) position: , mismatch: 8, identity: 0.758

-cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gtaacg-ggcggcgagccggtcggcgcgctcctg	Protospacer
 ..**. *.************** ****.**** 

245. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_CP048048 (Clavibacter michiganensis subsp. capsici strain 1106 plasmid pCM2_1106, complete sequence) position: , mismatch: 8, identity: 0.758

-cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gtaacg-ggcggcgagccggtcggcgcgctcctg	Protospacer
 ..**. *.************** ****.**** 

246. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 8, identity: 0.758

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
ggacacgacgtcgagccggttgtcgacatgctc	Protospacer
 ********* *********.****   * **.

247. spacer 22.1|6441980|32|NC_017186|CRISPRCasFinder matches to NZ_CP053712 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.75

tgcacgaccggccaatcgaccgccttgtagtc	CRISPR spacer
agcacgaccggccaatcgagcacctgatcgat	Protospacer
 ****************** *.*** .* * .

248. spacer 22.1|6441980|32|NC_017186|CRISPRCasFinder matches to NZ_CP014581 (Burkholderia sp. OLGA172 plasmid pOLGA2, complete sequence) position: , mismatch: 8, identity: 0.75

tgcacgaccggccaatcgaccgccttgtagtc	CRISPR spacer
tgttcgaccgcccaatcgaccgcattgatacc	Protospacer
**. ****** ************ ***  ..*

249. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NC_016624 (Azospirillum lipoferum 4B plasmid AZO_p5, complete sequence) position: , mismatch: 8, identity: 0.75

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gagctggccgacttcatcggcctggacacctg	Protospacer
 .* *********** ************  . 

250. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP029356 (Azospirillum sp. CFH 70021 plasmid unnamed1) position: , mismatch: 8, identity: 0.75

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gagctggccgacttcatcggcctggacacctg	Protospacer
 .* *********** ************  . 

251. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
tgggtggccgaattcctgggcctgcccgacgc	Protospacer
*********** ***** ******  *.*  .

252. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP029363 (Streptomyces globisporus strain TFH56 plasmid pTFSG2, complete sequence) position: , mismatch: 8, identity: 0.75

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gagatggccgactgcttcggcctggacccggt	Protospacer
 .*.********* *.***********  * *

253. spacer 26.6|8280108|34|NC_017186|CRT matches to NZ_LR594691 (Variovorax sp. WDL1 plasmid 3) position: , mismatch: 8, identity: 0.765

ctgggttcggctcggctcggctcggctcggctcg	CRISPR spacer
cgccctgcggctcggctcggctcggctcggccgt	Protospacer
*    * ************************.  

254. spacer 26.6|8280108|34|NC_017186|CRT matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

ctgggt--tcggctcggctcggctcggctcggctcg	CRISPR spacer
--gggccgccggctcggctcggcttggcccggctgc	Protospacer
  ***.  .***************.***.*****  

255. spacer 16.1|5356410|34|NC_017186|CRISPRCasFinder matches to NZ_CP040823 (Paraoceanicella profunda strain D4M1 plasmid pD4M1E, complete sequence) position: , mismatch: 9, identity: 0.735

ctccgacgcaaccgggcgccccgatgtctcgaca	CRISPR spacer
gggcgtccggacagggcgccccgatgtcccgaca	Protospacer
   ** *  .** ***************.*****

256. spacer 19.2|6436868|31|NC_017186|CRISPRCasFinder matches to NZ_CP032324 (Azospirillum brasilense strain MTCC4035 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.71

tgcccgtggcggaacctgatcgtcaccaagc	CRISPR spacer
ggcccgtcgctgaacctgatcgtcctggaaa	Protospacer
 ****** ** ************* . .*. 

257. spacer 19.3|6436928|32|NC_017186|CRISPRCasFinder matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gcgccttcgtcccagctggccggctcgacgat	CRISPR spacer
aaggcttcgtcccagcttaccggctcgaactc	Protospacer
. * ************* .*********   .

258. spacer 19.3|6436928|32|NC_017186|CRISPRCasFinder matches to NZ_AP022333 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49a, complete sequence) position: , mismatch: 9, identity: 0.719

gcgccttcgtcccagctggccggctcgacgat	CRISPR spacer
tgacgatcgtcccagcgggccggctcggcggc	Protospacer
  .*  ********** **********.**..

259. spacer 19.3|6436928|32|NC_017186|CRISPRCasFinder matches to NC_022049 (Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence) position: , mismatch: 9, identity: 0.719

gcgccttcgtcccagctggccggctcgacgat	CRISPR spacer
atgacctcgtcccagctggcgggcacgacctg	Protospacer
..* *.************** *** ****   

260. spacer 19.6|6437107|30|NC_017186|CRISPRCasFinder matches to MN317029 (Aeromonas phage vB_AhyS-A18P4, complete genome) position: , mismatch: 9, identity: 0.7

caggccgactacgagaagcagagcccgcag	CRISPR spacer
gaggccgactacgagaagcagaatttctgc	Protospacer
 *********************.... .. 

261. spacer 19.7|6437166|32|NC_017186|CRISPRCasFinder matches to NZ_CP042825 (Rhizobium sp. WL3 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

atcccgcagtagcgacaggtgtcgccgtcgcg	CRISPR spacer
tgattgccatagcgacaggtatcgccatcgcg	Protospacer
   ..** .***********.*****.*****

262. spacer 19.8|6437227|32|NC_017186|CRISPRCasFinder matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 9, identity: 0.719

cacacgatcggcggtttcacccgaccttcgcg	CRISPR spacer
attccgatcggcgatttcacccgacctaagac	Protospacer
  . *********.*************  *  

263. spacer 19.8|6437227|32|NC_017186|CRISPRCasFinder matches to NC_014838 (Pantoea sp. At-9b plasmid pPAT9B01, complete sequence) position: , mismatch: 9, identity: 0.719

cacacgatcggcggtttcacccgaccttcgcg	CRISPR spacer
cacacgatcggcggttttacgcgcaaaaccca	Protospacer
*****************.** **     * *.

264. spacer 19.10|6437349|32|NC_017186|CRISPRCasFinder matches to MT889391 (Mycobacterium phage MiniMac, complete genome) position: , mismatch: 9, identity: 0.719

gtctcgaacgtcgtgggcgagacgacgtgctc	CRISPR spacer
ataccgaacgtcgtgggcgagaagccggaaac	Protospacer
.* .****************** * ** .  *

265. spacer 19.11|6437410|32|NC_017186|CRISPRCasFinder matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 9, identity: 0.719

gacttcaagctgcgcctggtcaccctcggcgt	CRISPR spacer
cggtcggtgctgcacctggtcaccctcggcgc	Protospacer
 . *. . *****.*****************.

266. spacer 19.11|6437410|32|NC_017186|CRISPRCasFinder matches to NC_006362 (Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence) position: , mismatch: 9, identity: 0.719

gacttcaagctgcgcctggtcaccctcggcgt	CRISPR spacer
cgctcggtgctgcacctggtcactctcggcgc	Protospacer
 .**. . *****.*********.*******.

267. spacer 19.11|6437410|32|NC_017186|CRISPRCasFinder matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 9, identity: 0.719

gacttcaagctgcgcctggtcaccctcggcgt	CRISPR spacer
cggtcgatgctgcacctgatcaccctcggcgc	Protospacer
 . *. * *****.****.************.

268. spacer 19.15|6437657|32|NC_017186|CRISPRCasFinder matches to NC_022877 (Bacillus thuringiensis YBT-1518 plasmid pBMB0232, complete sequence) position: , mismatch: 9, identity: 0.719

tacgtgtacgttggcgcctacggaacaggaac	CRISPR spacer
taactgtacgttggtgcctacggtacaatcta	Protospacer
**  **********.******** ***.    

269. spacer 19.15|6437657|32|NC_017186|CRISPRCasFinder matches to NC_022877 (Bacillus thuringiensis YBT-1518 plasmid pBMB0232, complete sequence) position: , mismatch: 9, identity: 0.719

tacgtgtacgttggcgcctacggaacaggaac	CRISPR spacer
taactgtacgttggtgcctacggtacaatcta	Protospacer
**  **********.******** ***.    

270. spacer 20.3|6438753|33|NC_017186|PILER-CR,CRT matches to MH067969 (Arthrobacter sp. strain ANT_H2 plasmid pA2H2, complete sequence) position: , mismatch: 9, identity: 0.727

cacggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
ctgggtggcggtggcctgatgatcctgtcccag	Protospacer
*  *************** **** ***  *   

271. spacer 20.5|6438693|32|NC_017186|CRISPRCasFinder matches to NC_012527 (Deinococcus deserti VCD115 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

tggttgatccggatgtcccagtcgtccaccgc	CRISPR spacer
ccgaacagccggatgtgccagtcgtccagcgt	Protospacer
. *   * ******** *********** **.

272. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to MH067969 (Arthrobacter sp. strain ANT_H2 plasmid pA2H2, complete sequence) position: , mismatch: 9, identity: 0.719

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
tgggtggcggtggcctgatgatcctgtcccag	Protospacer
  *************** **** ***  *   

273. spacer 20.6|6438754|32|NC_017186|CRISPRCasFinder matches to NZ_CP013125 (Pseudomonas mendocina S5.2 plasmid pPME5, complete sequence) position: , mismatch: 9, identity: 0.719

acggtggcggtggcctgctgatactgggcgtc	CRISPR spacer
gccacaaccgtggcctgctgatcctggccgtc	Protospacer
.* ....* ************* **** ****

274. spacer 20.7|6438815|32|NC_017186|CRISPRCasFinder matches to NC_004808 (Streptomyces rochei plasmid pSLA2-L DNA, complete sequence) position: , mismatch: 9, identity: 0.719

gacggttggggcaacctgaaggcggccggcct	CRISPR spacer
tccacctggcgcatcctgaaggcggccggctg	Protospacer
  *. .*** *** ****************. 

275. spacer 20.7|6438815|32|NC_017186|CRISPRCasFinder matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 9, identity: 0.719

gacggttggggcaacctgaaggcggccggcct	CRISPR spacer
gagaccgcaggccgcctgaaggcggccggcct	Protospacer
** . .  .*** .******************

276. spacer 20.7|6438815|32|NC_017186|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 9, identity: 0.719

gacggttggggcaacctgaaggcggccggcct	CRISPR spacer
gagaccgcaggccgcctgaaggcggccggcct	Protospacer
** . .  .*** .******************

277. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP028972 (Aminobacter sp. MSH1 plasmid pUSP4, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
ctactgccgcgctcgacgaaaacctcgcccgg	Protospacer
 .. **************** ******..*  

278. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

279. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

280. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

281. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

282. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

283. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

284. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

285. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

286. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

287. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

288. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

289. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tggatgccgcgctcgaagagcacctcataggg	Protospacer
  ************** **.******.*    

290. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tggatgccgcgctcgaagagcacctcataggg	Protospacer
  ************** **.******.*    

291. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

292. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

293. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

294. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

295. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

296. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

297. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

298. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

299. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tcgatgccgcgatcgaagaacaccttggaata	Protospacer
 ********** **** ********.*   . 

300. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

301. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

302. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

303. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

304. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

305. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

306. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

307. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

308. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

309. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

310. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

311. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

312. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

313. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

314. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

315. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

316. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

317. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

318. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

319. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

320. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

321. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

322. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

323. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

324. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

325. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

326. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

327. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

328. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gtgatgccgagcttgacgaacaccttgcgcag	Protospacer
..******* ***.***********.*. *  

329. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

330. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

331. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

332. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

333. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

334. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

335. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

336. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

337. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

338. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

339. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

340. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gagatgccgcgctcgccgaactccttggatgc	Protospacer
. ************* ***** ***.*  . *

341. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

342. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

343. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 9, identity: 0.719

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcctcgccgcgctcgacgatcatctcgtacgt	Protospacer
.*  .************** **.***** * .

344. spacer 21.2|6441506|32|NC_017186|CRISPRCasFinder matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 9, identity: 0.719

tcggccagcacccggcggaggttccggatact	CRISPR spacer
ggcgacagcacccggcggagcttgcggagccg	Protospacer
   * *************** ** ****  * 

345. spacer 21.2|6441506|32|NC_017186|CRISPRCasFinder matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

tcggccagcacccggcggaggttccggatact	CRISPR spacer
tcggccagcacccggacgaggttgagtccccg	Protospacer
***************  ******  *  . * 

346. spacer 21.3|6441567|32|NC_017186|CRISPRCasFinder matches to MN855771 (Siphoviridae sp. isolate 189, complete genome) position: , mismatch: 9, identity: 0.719

atcgattcgctgaggacctccggcagcacgat	CRISPR spacer
gacatcgcgctgatgaccttcggcagcacgaa	Protospacer
. *. . ****** *****.*********** 

347. spacer 21.3|6441567|32|NC_017186|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 9, identity: 0.719

atcgattcgctgaggacctccggcagcacgat	CRISPR spacer
ccggattcgcggaggatctccggcagggtgag	Protospacer
 . ******* *****.********* ..** 

348. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_010721 (Methylorubrum populi BJ001 plasmid pMPOP02, complete sequence) position: , mismatch: 9, identity: 0.719

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gtcgccggccagcccgagacgatcctcggccg	Protospacer
  *.***** ********.********.  *.

349. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_015974 (Sphingobium sp. SYK-6 plasmid pSLPG, complete sequence) position: , mismatch: 9, identity: 0.719

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
accccgggcgagcccgaggcgatcttcactgc	Protospacer
  * * ***.**************.****   

350. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NZ_CP005085 (Sphingobium sp. TKS plasmid pTK1, complete sequence) position: , mismatch: 9, identity: 0.719

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
accccgggcgagcccgaggcgatcttcactgc	Protospacer
  * * ***.**************.****   

351. spacer 21.5|6441689|32|NC_017186|CRISPRCasFinder matches to NC_009621 (Sinorhizobium medicae WSM419 plasmid pSMED02, complete sequence) position: , mismatch: 9, identity: 0.719

cacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
gaagccggcacgcccgaggcgatcttcgacaa	Protospacer
 * .****** *************.**.   *

352. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP012185 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-2, complete sequence) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cggagttcggcgagcccgtcgtcgcgttcccg	Protospacer
 . *   ********* *************. 

353. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP025552 (Streptomyces rimosus strain WT5260 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
tgcacggcgtcgagccggtcgtcgccggcttc	Protospacer
 .****.** ***************   *.*.

354. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP012182 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-1, complete sequence) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cggagttcggcgagcccgtcgtcgcgttcccg	Protospacer
 . *   ********* *************. 

355. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP022567 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK03, complete sequence) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aactcgacggcgagccggccgtcgcggaagaa	Protospacer
.** **************.*******      

356. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MK224497 (Mycobacterium phage Henu3, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

357. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to KJ944841 (Mycobacterium phage Cheetobro, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

358. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MN945904 (Mycobacterium phage Eponine, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

359. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to AP018469 (Mycobacterium phage Y10 DNA, complete genome, note: sample1) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

360. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MF140402 (Mycobacterium phage Chancellor, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

361. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to AP018470 (Mycobacterium phage Y2 DNA, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

362. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to KT361920 (Mycobacterium phage Slarp, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

363. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MT310882 (Mycobacterium phage JF1, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

364. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to AP018471 (Mycobacterium phage Y10 DNA, complete genome, note: sample2) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

365. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MH051258 (Mycobacterium phage SamScheppers, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

366. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MF140435 (Mycobacterium phage Wintermute, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

367. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_027365 (Mycobacterium virus Fionnbarth, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aggacgacgacgagccggtcgtcgcggccgcc	Protospacer
.. ******.**************** .* ..

368. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_011892 (Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
atcacgacggcgagccgggcgacgcggacgcg	Protospacer
. **************** ** ****  * . 

369. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_047992 (Microbacterium phage Zeta1847, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cgcatgacggcgagccggtggtcgcggtggcg	Protospacer
 .**.************** ****** *  . 

370. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP013538 (Rhizobium phaseoli strain R630 plasmid pRphaR630a, complete sequence) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
tcccagacgacgcgccggtcgtcgcgtttcgg	Protospacer
  *  ****.** ***************.*  

371. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
acgacgacgaccagccggtcgtcgcggccatg	Protospacer
.  ******.* ************** .* * 

372. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP034999 (Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence) position: , mismatch: 9, identity: 0.719

gacacga----cggcgagccggtcgtcgcgttcctt	CRISPR spacer
----tgatgttcggcgagccgatcgtcgcgctccag	Protospacer
    .**    **********.********.***  

373. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP050090 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b4, complete sequence) position: , mismatch: 9, identity: 0.719

gacacga----cggcgagccggtcgtcgcgttcctt	CRISPR spacer
----tgatgttcggcgagccggtcgtcgcactccag	Protospacer
    .**    ******************..***  

374. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MK433264 (Gordonia phage Tiamoceli, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cggccgacggcgtgccggtcgtcgggtggcta	Protospacer
 .  ******** *********** **  ** 

375. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MT952843 (Gordonia phage Twonlo, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cggccgacggcgtgccggtcgtcgggtggcta	Protospacer
 .  ******** *********** **  ** 

376. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to MK977704 (Gordonia Terrae phage RoadKill, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cggccgacggcgtgccggtcgtcgggtggcta	Protospacer
 .  ******** *********** **  ** 

377. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to KR053200 (Gordonia phage GTE6, complete genome) position: , mismatch: 9, identity: 0.719

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
cggccgacggcgtgccggtcgtcgggtggcta	Protospacer
 .  ******** *********** **  ** 

378. spacer 21.7|6441444|33|NC_017186|CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 9, identity: 0.727

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
ggtgacgccgcgctcggcgaacacctcgcgggc	Protospacer
 ..**.**********.***********.   *

379. spacer 21.11|6441688|33|NC_017186|CRT matches to NC_016165 (Rhodobacter phage RcapMu, complete genome) position: , mismatch: 9, identity: 0.727

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
tcatctcgacaagcccgaagcgatcctcaccgc	Protospacer
.**. .**.*********.***********   

380. spacer 21.11|6441688|33|NC_017186|CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 9, identity: 0.727

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
tcatctcgacaagcccgaagcgatcctcaccgc	Protospacer
.**. .**.*********.***********   

381. spacer 21.11|6441688|33|NC_017186|CRT matches to NZ_CP022747 (Sphingobium hydrophobicum strain C1 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

ccacaccggcaagcccgaggcgatcctcacgca	CRISPR spacer
tggcgacggcaagcccgaggctatcatcacaga	Protospacer
. .*. *************** *** ****. *

382. spacer 21.12|6441749|33|NC_017186|CRT matches to NC_006911 (Streptomyces sp. F11 plasmid pFP11, complete sequence) position: , mismatch: 9, identity: 0.727

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
acccgcgacggcgagccggtcaccgcgttcggc	Protospacer
   *.****************..*******  .

383. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gaccacgacgacgagcctgtcgtcgcggccgtg	Protospacer
 . *******.****** ********* .* * 

384. spacer 21.12|6441749|33|NC_017186|CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 9, identity: 0.727

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gaccacgacgacgagcctgtcgtcgcggccgtg	Protospacer
 . *******.****** ********* .* * 

385. spacer 22.1|6441980|32|NC_017186|CRISPRCasFinder matches to NZ_CP014169 (Sphingomonas panacis strain DCY99 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

tgcacgaccggccaatcgaccgccttgtagtc	CRISPR spacer
agcaggaccggccaatcgacagcccgacagaa	Protospacer
 *** *************** ***. ..**  

386. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gaactggccgacttcatcggcctggacacctg	Protospacer
 .. *********** ************  . 

387. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP054620 (Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gaactggccgacttcatcggcctggacacctg	Protospacer
 .. *********** ************  . 

388. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP013531 (Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
ctggcggccgatttcctcggcctggcggatca	Protospacer
. **.******.*************  .* * 

389. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP013584 (Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
ctggcggccgatttcctcggcctggcggatca	Protospacer
. **.******.*************  .* * 

390. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
cgggtggccgcgttcctcggcctgtcctaaga	Protospacer
.*********  ************  * *.  

391. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
ctggcggccgatttcctcggcctggcggatca	Protospacer
. **.******.*************  .* * 

392. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gagctggccgacttcatcgggctggacacctg	Protospacer
 .* *********** **** *******  . 

393. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP021127 (Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
ctggcggccgacttcctcgacctggcggatca	Protospacer
. **.**************.*****  .* * 

394. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
cgcatggtcgactttctcggcctggacatttg	Protospacer
.* .***.******.*************  . 

395. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
cgcatggtcgactttctcggcctggacatctg	Protospacer
.* .***.******.*************  . 

396. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gcgctggccgacttcctccgcctcgacgacga	Protospacer
  * ************** **** ***.*   

397. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
ctggcggccgatttcctcggcctggcagatcg	Protospacer
. **.******.*************  .* * 

398. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_LR594676 (Variovorax sp. PBS-H4 plasmid 2) position: , mismatch: 9, identity: 0.719

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
tacatcttcgacttcctcgacctggacgagcg	Protospacer
*. .*  .***********.*******.*** 

399. spacer 26.6|8280108|34|NC_017186|CRT matches to NC_013859 (Azospirillum sp. B510 plasmid pAB510e, complete sequence) position: , mismatch: 9, identity: 0.735

ctgggttcggctcggctcggctcggctcggctcg	CRISPR spacer
accggcccggctcggctcggcccggcccggccgg	Protospacer
 . **..**************.****.****. *

400. spacer 26.6|8280108|34|NC_017186|CRT matches to MN693688 (Marine virus AFVG_250M167, complete genome) position: , mismatch: 9, identity: 0.735

ctgggttcggctcggctcggctcggctcggctcg	CRISPR spacer
gctagtcgggctcggctcggctcgactcgacttg	Protospacer
 . .**. ****************.****.**.*

401. spacer 19.3|6436928|32|NC_017186|CRISPRCasFinder matches to NZ_CP031947 (Ruegeria sp. AD91A plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gcgccttcgtcccagctggccggctcgacgat	CRISPR spacer
aaagcttcatcccagctgaccggctcgaactc	Protospacer
. . ****.*********.*********   .

402. spacer 19.8|6437227|32|NC_017186|CRISPRCasFinder matches to NZ_CP022370 (Bosea sp. AS-1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

cacacgatcggcggtttcacccgaccttcgcg	CRISPR spacer
ggccatggcggcggtttcacacgacctgcgca	Protospacer
 .*   . ************ ****** ***.

403. spacer 19.20|6436988|34|NC_017186|CRT matches to NZ_CP020812 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.706

cagggagatcgacacgtcggacagcgtttcgcgg	CRISPR spacer
tgcggtcgccgacacgtcggacagcgttacccgc	Protospacer
.. **  ..******************* * ** 

404. spacer 19.23|6437165|37|NC_017186|CRT matches to MH834621 (Arthrobacter phage Nandita, complete genome) position: , mismatch: 10, identity: 0.73

gatcccgcagtagcgacaggtgtcgccgtcgcggttt	CRISPR spacer
tttgaggcagtagcggcaggagtcgccgtcgcggagc	Protospacer
  *   *********.**** *************  .

405. spacer 19.23|6437165|37|NC_017186|CRT matches to MH834627 (Arthrobacter phage Ryan, complete genome) position: , mismatch: 10, identity: 0.73

gatcccgcagtagcgacaggtgtcgccgtcgcggttt	CRISPR spacer
cttgaggcagtagcggcaggagtcgccgtcgcggagc	Protospacer
  *   *********.**** *************  .

406. spacer 20.5|6438693|32|NC_017186|CRISPRCasFinder matches to NZ_CP017304 (Rhodococcus sp. YL-1 plasmid pYLL2 sequence) position: , mismatch: 10, identity: 0.688

tggttgatccggatgtcccagtcgtccaccgc	CRISPR spacer
aggttgttccagatgtcccagtcggtgtggac	Protospacer
 ***** ***.************* .    .*

407. spacer 20.5|6438693|32|NC_017186|CRISPRCasFinder matches to NC_005073 (Rhodococcus erythropolis linear plasmid pBD2, complete sequence) position: , mismatch: 10, identity: 0.688

tggttgatccggatgtcccagtcgtccaccgc	CRISPR spacer
aggttgttccagatgtcccagtcggtgtagac	Protospacer
 ***** ***.************* .    .*

408. spacer 20.8|6438814|33|NC_017186|CRT matches to NC_004808 (Streptomyces rochei plasmid pSLA2-L DNA, complete sequence) position: , mismatch: 10, identity: 0.697

agacggttggggcaacctgaaggcggccggcct	CRISPR spacer
ctccacctggcgcatcctgaaggcggccggctg	Protospacer
   *. .*** *** ****************. 

409. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to KY945355 (Mycobacterium phage Shandong1, complete genome) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
caaccgccgcggtcggcgaacacctcgttgag	Protospacer
  . .****** ***.*************   

410. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP031117 (Rubrobacter indicoceani strain SCSIO 08198 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcgacgccgcgctcgacgagcaccctgccgaa	Protospacer
.***.**************.****..*..   

411. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP020740 ([Pseudomonas] mesoacidophila strain ATCC 31433 plasmid pATCC31433, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcgatgccgcgctcgacgatcgcccaccgcag	Protospacer
.****************** *.**.  . *  

412. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NC_017324 (Sinorhizobium meliloti BL225C plasmid pSINMEB01, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

413. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

414. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gcattgccgcgctcgaagaagacctcggcgtg	Protospacer
.*. ************ *** ****** . . 

415. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

416. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

417. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

418. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to CP016643 (Mycobacterium sp. djl-10 plasmid djl-10_3, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
ttgatgccgtgctcgacgatcaccttcgaatc	Protospacer
 .*******.********* *****.    .*

419. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP021794 (Sinorhizobium meliloti strain USDA1157 plasmid psymA, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

420. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

421. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 10, identity: 0.688

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgagtgccgcgctcgacggagacctcgaccga	Protospacer
  ..**************.* ****** .*  

422. spacer 21.4|6441628|32|NC_017186|CRISPRCasFinder matches to CP000663 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence) position: , mismatch: 10, identity: 0.688

gtgaagggcctctccccggccgggcagcggta	CRISPR spacer
gctccgggccccgccccggccgggcagcccgc	Protospacer
*.   *****.* ***************    

423. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP013381 (Burkholderia sp. Bp5365 strain MSMB43 plasmid pMSMB43, complete sequence) position: , mismatch: 10, identity: 0.688

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
tcggcgccggcgagccgggcgtcgcgtatcag	Protospacer
   .** *********** ******** .*  

424. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_011143 (Phenylobacterium zucineum HLK1 plasmid, complete sequence) position: , mismatch: 10, identity: 0.688

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gcgacgacggtcagccggtcgtcgcgccagcc	Protospacer
*  *******. **************..  ..

425. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 10, identity: 0.688

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
ggtggtacggcgcgccgttcgtcgcgttcgaa	Protospacer
*...  ****** **** ***********   

426. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP009547 (Burkholderia sp. 2002721687 plasmid pBTU, complete sequence) position: , mismatch: 10, identity: 0.688

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
tcggcgccggcgagccgggcgtcgcgtatcag	Protospacer
   .** *********** ******** .*  

427. spacer 21.7|6441444|33|NC_017186|CRT matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 10, identity: 0.697

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
atggatgccgcgctcgaagagcacctcataggg	Protospacer
   ************** **.******.*    

428. spacer 21.7|6441444|33|NC_017186|CRT matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 10, identity: 0.697

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
atggatgccgcgctcgaagagcacctcataggg	Protospacer
   ************** **.******.*    

429. spacer 21.7|6441444|33|NC_017186|CRT matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
gtcgatgccgcgatcgaagaacaccttggaata	Protospacer
  ********** **** ********.*   . 

430. spacer 21.7|6441444|33|NC_017186|CRT matches to KY945355 (Mycobacterium phage Shandong1, complete genome) position: , mismatch: 10, identity: 0.697

cacgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
ccaaccgccgcggtcggcgaacacctcgttgag	Protospacer
*  . .****** ***.*************   

431. spacer 21.9|6441566|33|NC_017186|CRT matches to MN855771 (Siphoviridae sp. isolate 189, complete genome) position: , mismatch: 10, identity: 0.697

gatcgattcgctgaggacctccggcagcacgat	CRISPR spacer
cgacatcgcgctgatgaccttcggcagcacgaa	Protospacer
 . *. . ****** *****.*********** 

432. spacer 21.12|6441749|33|NC_017186|CRT matches to NZ_CP022567 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK03, complete sequence) position: , mismatch: 10, identity: 0.697

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
aaactcgacggcgagccggccgtcgcggaagaa	Protospacer
 .** **************.*******      

433. spacer 21.12|6441749|33|NC_017186|CRT matches to NC_011892 (Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence) position: , mismatch: 10, identity: 0.697

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
tatcacgacggcgagccgggcgacgcggacgcg	Protospacer
.. **************** ** ****  * . 

434. spacer 21.12|6441749|33|NC_017186|CRT matches to NC_047992 (Microbacterium phage Zeta1847, complete genome) position: , mismatch: 10, identity: 0.697

cgacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gcgcatgacggcgagccggtggtcgcggtggcg	Protospacer
  .**.************** ****** *  . 

435. spacer 22.1|6441980|32|NC_017186|CRISPRCasFinder matches to MH992209 (Apis mellifera associated microvirus 17 isolate INH_SP_257, complete genome) position: , mismatch: 10, identity: 0.688

tgcacgaccggccaatcgaccgccttgtagtc	CRISPR spacer
ggcacgaccggcctatcggccgccggatttaa	Protospacer
 ************ ****.*****  .*    

436. spacer 22.2|6442041|32|NC_017186|CRISPRCasFinder matches to NZ_CP032827 (Sphingomonas sp. YZ-8 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

acgaagtagatgcccgcgtgctggatggtgag	CRISPR spacer
taccggccgatgcgcgcctgctggatggtgac	Protospacer
    .*. ***** *** ************* 

437. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NC_015951 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gacgtggccgtgttcctcggcctggacgtcgg	Protospacer
 . *******  ***************.    

438. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP016084 (Streptomyces sp. SAT1 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gacgtgggcgtcttcctcggcctggacgtcgg	Protospacer
 . **** ** ****************.    

439. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gaactggcggacttcatcggcctggacacctg	Protospacer
 .. **** ****** ************  . 

440. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP024427 (Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
agggcggccgacatcctcggcctgttccgcga	Protospacer
 ***.******* ***********  * .   

441. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP039425 (Citricoccus sp. SGAir0253 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
tactaccccgacttcatcgccctggacaagga	Protospacer
*.     ******** *** **********  

442. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP020443 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
agggcggccgacatcctcggcctgttccgcga	Protospacer
 ***.******* ***********  * .   

443. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NZ_CP039430 (Citricoccus sp. SGAir0453 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
tactaccccgacttcatcgccctggacaagga	Protospacer
*.     ******** *** **********  

444. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to MN062714 (Microbacterium Phage DirtyBubble, complete genome) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
aacctggccaacctcctcggcctggactcccc	Protospacer
 .  *****.**.**************   *.

445. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to MT024860 (Microbacterium phage Stromboli, complete genome) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
aacctggccaacctcctcggcctggactcccc	Protospacer
 .  *****.**.**************   *.

446. spacer 22.4|6442162|32|NC_017186|CRISPRCasFinder matches to NC_016435 (Gordonia phage GRU1, complete genome) position: , mismatch: 10, identity: 0.688

tgggtggccgacttcctcggcctggacaagct	CRISPR spacer
gatgaggctgacttcctcggcctgcacagcgg	Protospacer
 . * ***.*************** ***.   

447. spacer 21.1|6441445|32|NC_017186|CRISPRCasFinder matches to MK305889 (Gordonia phage Mutzi, complete genome) position: , mismatch: 11, identity: 0.656

acgatgccgcgctcgacgaacacctcgttccc	CRISPR spacer
tgattgccgccctcgccgaacacctcggcgag	Protospacer
  . ****** **** *********** .   

448. spacer 21.2|6441506|32|NC_017186|CRISPRCasFinder matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 11, identity: 0.656

tcggccagcacccggcggaggttccggatact	CRISPR spacer
ctctccagcacccggcggcggttcgggtccag	Protospacer
..  ************** ***** ** .   

449. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 11, identity: 0.656

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
agggttttcgcgacccggtcgacgcgttcctt	Protospacer
.. ..  . **** ******* **********

450. spacer 21.6|6441750|32|NC_017186|CRISPRCasFinder matches to KX815338 (Streptomyces phage Joe, complete genome) position: , mismatch: 11, identity: 0.656

gacacgacggcgagccggtcgtcgcgttcctt	CRISPR spacer
gacacgacggccagccgatcgtcatcgctgac	Protospacer
*********** *****.*****..  ..  .

451. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NC_017327 (Sinorhizobium meliloti SM11 plasmid pSmeSM11c, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

452. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

453. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP021801 (Sinorhizobium meliloti strain USDA1021 plasmid psymA, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

454. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

455. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

456. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

457. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP019483 (Sinorhizobium meliloti strain B401 plasmid pSymA, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

458. spacer 10.1|2899133|29|NC_017186|CRISPRCasFinder matches to NZ_CP019486 (Sinorhizobium meliloti strain B399 plasmid pSymA, complete sequence) position: , mismatch: 12, identity: 0.586

-----gtccgatcgcccgggcgctcagcggtgcc	CRISPR spacer
gcgaccgctgatcgcccgggcaatcgtcg-----	Protospacer
       *.************. **. **     

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1538493 : 1582883	43	Acinetobacter_phage(28.57%)	integrase,transposase	attL 1538692:1538710|attR 1589764:1589782
DBSCAN-SWA_2	4670147 : 4677779	7	Bacillus_phage(16.67%)	NA	NA
DBSCAN-SWA_3	6405357 : 6460869	43	Acinetobacter_phage(100.0%)	transposase,integrase	attL 6399763:6399783|attR 6441361:6441381
DBSCAN-SWA_4	8559516 : 8633698	59	Salmonella_phage(14.29%)	transposase,protease,tRNA,integrase	attL 8555328:8555345|attR 8590943:8590960

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017186|1538493:1582883|DBSCAN-SWA
CATGCCTCCTCGCAAGCGCCGGTCGTACCCGGCGGAGTACAAGGTCGAGGCTGCTCACCGCGTGATCGATTCCGGCCGGACGATCGCGGAGGTCGCCCGCGAGCTGGGTCTCGACGCGGGCATGCTGAGTGTCTGGGTCAAGGACGAGCGGCGCCGGGTGACCGCGGCCGAGGTGCACGGCGAGAACCCTCTGGAGGCGGCCGAGCGGGCCGAGCTGCTGCGGCTGCGCGGGCAGGTGGCCGAGCTGGAGAAGGACAACGCGTTCCTGGTAAAAGCCTCGGCGTACTTTGCCGCGATGCAGAAGAACCGGCCCGGTTCGCTCTGATGGCCAAGTACGCCGGCCCCGACGAGTCCGCCGACACTGCCGGCAGGGTCCCACTTCGGAACGAACGTCGGTTCTCGGTCCGGCGCATGGCGCGACTGCTGAATGTGTCGAGGTCCGGCTACTACGCACACGCCACACGCGCCGCCGCAACGGTCCTGGCGCCGCGCCGGCAACGCCGGGCCGACCTGGAGGTGAAGATCACCCAGGCGCACCAGGACTCCGGTGGCACTTACGGGTCGCCGCGTATCACCGCGGAACTTCGCGACCAGGGCGAGGTGGTCACGGCGAAGACGGTTGCCAAGATCATGGCCGGGGTGGGGCTGGAGGGCATCAGTCCGCGCACGTTCAAGGTGCGCACGACGGTGGTCGATCCGGCCGCGTCGTTCCCGCCGGACCTGGTCGGCCGGCACTTCGACCGGGGCCGGACCGACGCGGTCTGGCTGACCGACATCACGTATCTGACGTGTGGTGAGGGCGACATGTTCCTGTGTGCGATTCGGGACGGTCATTCCCGGAAAGTGCTGGGCTACAGCGTTTCTGACCACATCAGCGCCGAGATGGTCACTGCCGCCATCGACGACGCGGTGGCCGGCCGGGGCAGCGGGTGCCGCGGCACGATTCTGCATTCGGACCGCGGCGGCGAGTTCACGGCGAACGTGACGGCGCAGGCATGCTTCGGTCACGGGCTGCGCCGGTCGATGGGCGAGACCGGGATCTGCTGGGACAACAGCCCGGCGGAATCATTCTGGTCGACGTTCAAACATGAGGAATACTACCGGCACGTCTACGCGACGAAAACGGAACTCGTTGCCGCGATTGACAAATGGCTGAATTTCTACAACAGTAGGCGGCGCCACTCCTCGATCGGGATGCTCAGCCCCAACGACTACGAGAAGTCGCTGCCAGTGGTTGCTTGAACTGTGTAAGCCCCTGTCCACCGTTCGGGGTGAACCTCACAGCAGATCGATGACGCGTTGCGGGCCGTTGCCCGCAAGAAGGTGCCGTTCGAAGGCACGTGGACCAAGGCGCCCTACCCGGAGCGTTCCCACGACGGCCGGACCTTCGCGGTCCTGGTCGACGACCCGGAGATCGAAGCGCTGGTGGTCGACCGGGCGACCGGCGAGGTCTTCGTCCTGGACGGCTCGGTCGGCCTGGTCAACCGGTCGTTGAGCCGGTTCGCCGAGTCCGCGGCGGCGTACGCGGCCGCGCGGAAGCGGGCGAAGTCCATCGACGAGGACGACGACGAGGCCCTCGAAGCCAACGGCGAACAGGCGTTGAAGGCCATCCGCGCGATCGACGCGGACGCCGTCGCAGACGAAAACCAGTTCTGGGCCGTCGCCACCGAGGAACTCGGCTACGGCATGTGAGACACCTGCGCGTCAGGACAGTCCCAGGCCGGCCATCCTGACGGAATTCCGGTGGTCACCACGGTGGCGTGCCGATGTCCGGACAGGCAAGTCTGGCAAGAAGAACGGGCACTTCTCCCCGGGCGCCGTCCTTTTTGGTGCGTCGTGGCCTCGGTCGGCGATGAAGTGAAATGGTCATGCAGGTGGAGTCGTCCATTTTGGGTCAGTCGATTATTGACATTCCGCCGCGCTCGATAATGGTGTGCGCAATCTGAAAGACTCGGGAAACGACAACGGATTGCGCGTTTCTGTCGGCGACAAATGGAGTTCGCATGCTCTTCGGTGACGGGAAAGTACGCGCCGACTACACGGATTTCGTGGAACGTCAGATCGCCGATGTCCGCCGTGTCCACGCCGGCGAAGAGGATCTTTCCGCCTCGCACGCGGAACCATCGGCAAGCCCCAACGGGGAACGGCTGGTGGCTCGGCATCCGGTCTGAGGACTGCGTTGCGCGATCGGCGTCGTGTCGCTGGTTCGGTCCCGCGGGAAGCCGTGGCAGCTGCGTTGCGGGACGGATGTGTCGAGGCGCGCGGATTCGAGGTGGTGCCGTGGTCGGCGCGACCAGCGACATGAGCGCGTGGTCGGGGATGATCACGCGGACGCCACGGCGACCGAGTGTGTAGCCTCGGCAGCTGTGAGCTGGCTGCCCGACGACTTCGTCCACCCCGTCTACACGCCCGTGCCCGGTACCGCGCTTCACCTGCGGCCGATCCGCGAGACGGACACTGCTATCGACTACCCCGCTGTGATGGGCTCCCGGGAGCGCTTGTGGAGCATCTTCGGTCCGGCCTGGTCATGGCCCAAGGAGACGATGACCTATGAAGAGGACCGCCTCGACCTGCTGCGGCACGAGAAGGAGATAGCCGCGCACCAGTCGTTCAACTATGCGCTGCTGGACGAGGAGGAGACCGCGATCCTGGGCTGTGTGTACATCGACCCGCCCGAGCGCACCGGTTCCGACGGCGAGGTGTCCTGGTGGGTGGTGGACGACCTCGTCGGCAGCGAGGTGGAGCGTGCGCTCGATGCGCTGGTGCCGCAGTGGATCGCCACCGACTGGCCCTTCCGCCGGCCCCGCTTTCTGGGCCGCGACATCACCTGGCAGGACTGGCTCGCGTTGCCACCGATCTCGTGACACTTCTCAAGCGGTAGCCGGATCGGCGGACTGTCGGCGGTAGCGACGAGGGAAGGCCACGGGGGCTTCAGGAGTTGTCGCGGGCGAGCAGGCCGTCGACGAGGAGTTGCAGCATCCGGGTGGCCTGGTCGGTGTCGGCGGCGGCCAGCATGATGCCGGCCATGCTGGCGGAGATGTCGGCCGGTCGGACGTCGGCGCGCAGGGTGCCGTCGGCCCGGCCGGCGTCGAGGATGGTGGCGATGGCGACCTCGAGACGCTCGCGGGTGTGGCCGGAGTTGAGCGCGCCGCTGGCGATCACCGCGCGCAGGGCTTCGGCCATGCCGCGTTTCGTGGCGACGAAGTCCTGGTAGCGGCGCATCCATTCGCGCATGGCGTCGGTCGGCGGAAGCTCGGTCACCAAGTCCGCGGCCATGGCACAGAGGCGGGCGAGTTCGCTGCGGTAGACCTCCTCGACCAAGGCGTCACGGGACGGGAAGTTGCGGTAGAGCGTGCCGACACCGACGCCCGCCTCGCGGGCGATGGCCTCGATCTTGACGGGGCCGGAGCCGGAGGTGAGGGCGCGGGTGGCCGCCTCCACGATGCGCCGGCGGTTGCGCTGGGCGTCGGTGCGGGTGCCAGGGCGTCGCTCGTCCTCGGAAACGGGATCACCTCACAAGCGGAATCGGTTCCGCTTCTGCTAGGGTCGGACAGGGTCAAGCGGAATCGGTTCCGCTTATGGTCATCGTAGCGGGAGGACCACGGCCATGACCGCATCGCGTGCGTCTGCGTACGGGAAACTGGGCGACCACGACGTGCTGAGGGTCGGCTTCGGTGCCATGCAGCTGGAACACGCCGACCCCGACGCTGCCGTCAGGGTGCTCCGTCGCGCGATCGAACTCGGTGTCGACCACGTCGACACGGCTCAGTTCTACGGGCCGGTCAATGACCTGATCAGGACCGCATTGCATCCGTACGCCGCCGGACTGCGGATTGTCACCAAGGTCGGCGCGGTGGCCCACGAGACCGAGCGGCTGGTCGCCGCCCAGAAGCCGGCGGAGCTGCGGGCGTCGGTCGAGGAGAACCTGCGCGCACTGGGTACCGACCACCTGGCGGTGGTCGATCTTCGCCGCGCCGACGTGCCGCCGGGCATTGTCGCCACCGGCGACCAGGTGGTCGATCTGGACAGTCAGCTGGCCGAACTGATCGCCCTGCGCGACGAGGGCAAGATCGGCGGCATCGGGCTGAGCCACGTCGACCTCGCCCAGCTGCGGCAGGCTCTTCCGGCCGGCATCGTCTGCGTCCAGAACCTGTACAACGTCCTCACCCGGGGCCACGAAGACGTGCTGACCGAGTGCGCCGAGCAGGGCATCGCCTGGGTGCCGTACTGCCCGCTCGGATCGGCTTTCGACCGGCTGCCCAGCGTCACCGACAACCCGGTCGTCCTCGCGCACGCCCGGCGCCTCGGCATCACCCCGGCTCAGGCCGGGCTGGCCTGGCTGCTCGGGCACAGCCCGGCCACGCTGCTGATACCCGGCACCCGCAACCTCGCGCACCTGGCCGACAACGTCGCGGTCGCCCGGATCGAGCTGGACCACGAAGCAACGACGGCCTTCGACGCTCTGGCCCAGGATGTGTCCGCTCAAGCGGACCTGGACGCGCATTCCGAGGCGTCGCGCCGATGACGGCCGAAATTCCCTGGCGTTCGCTTGCTGATCGAAATCCACCCCGATCCCGAACCCGGGCCGACCATGAGGATCCCCGCACGACGCTGACCCCGGGTGAGGAGAACGGCATGGGCTGTCAGGGCATCGGCACAAGACGTGGCTGATGCCGGCGGCGCTCCGATGTGACGGAGCGACCAGCAGCACGAGCGATTGCCGGCCGGTTGATGTGCAGGCGCTCGAAAGCCTGATCTCCTACACTCTCGCCATGTTCGAGTACCACGGCTGGATAACGCTTCGCTCGACCGCCGAAGCGCTCGACGATGAACCGCCACTCCGGCTCGGCGAGATCCAAGACCTGGTCGACGAGCTCGCTGGTTACGCGTTGATGGATCTTCAGCCGATGAACGGCACCTACTACATCCATCTGGGCGGGAACCCGAATCGCAGCGGGCAGCGCGGGCCGGCGGTGATCGACTTGTTCGCCAAGGTCGGCAGGCTTGCCCCCGGATCTTACGGGCTGCTGTACGTCCACGACGCCGACCACACGCTGAGCTTCCGTGTCTTCCGGCTGGTCCGGGGCACGGTCACCGAGCACCCGGACCACCTTTTGTCACCAGTGATCCCCACATTGGAAGACGCCGAGACGAGCTGACATCGCGGACCACGCGTGTTCGGCCGGCGCAGCGTCACCCTGGAACCGATGACAACCTGGTTCCGCACGCGGACGTTCTGAGGGGTATGCGGGTAGATCCCAGTTTCGAAGTGTTCGTCGAAGGCAGTTCGACGGCGTTGCTGCGCACCGCGTACCTGCTGACCGGCGACCGCGGGCACGCCGAGGACCTGTTGCAGACGGCGCTGTTGCGCACCGCCCGGCATTGGCCGCGGGCGCGTGACTCGCCTCAGGCGTATGCACGCACGGTGTTGCTGAACCTGTCGCGGGACCGGGTCAGGGCGTTGTTCCGGCGCCCGAGGGAGGCCCCGATGCCACCCGACGTGGACACGCTGCACGCGGTCGACGCCGGGTACGAGCAGGTCTCCGAGCGCCGCGTGGTGCTGCGCGCGCTGGCCGAACTGCCGATCCGCCAACGGCAGGTCATCGTGCTGCGCTTCTTCGAGGACATGTCCGTCGAGCAGACCGCCGGGCTGCTCGGCTTCAGCTCCGGGACGGTCAAGTCGCACACATCCCGGGCTTTGGCCAGGCTGCGCGAGCTGCTGGCCGACCACGACTCACTCCAGGAGGTTCCCCGTGCTCACCGATGAGCAGTACGGCCGCCGGATCGGTGACCGGCTGCGGCACGAGCTCGACGACGTCCACGCGAGCCCGGACCTGGTCCGCAAGCTCCGCCACCGCCGGACCAGGCGCACGTGGGCGATCACCGGTGCCATCGCCACCCCGGTGGCCGCCGCGGCCGTCGTCGCAGTGGTCGTCTCGACCCAGGCCACCCCCCACCGATCCACCACCGCAGCGCCCACCAGTGCGGCGTCCACCAGCGCTCAGCCCCGGATCGTCACCGTGGCGTACATCCAGGCGGAGACGGTGAAGGCACTCGGCCAGGGCACCCAGTACGTCATCTACTCGAAGGACACCTACGAGAGCGGCTACTACGAGACCTGGACCGACAAGGCGACCCAGCGGTACCGCAACGACATCTACACCCGCCTTCCGGCCGCCACCCAGGCGGGTCGCGCCGGGGACGGGAAGATGACCCTCCCGTCCGGCCCGCCCACAGCCCCGTCCGGGCCGCCCCACCGCCAACAGTCGCACGCCGTCAAAGGCCCGGGGGAGAGCCAGGAGATCACCACGGTCGACTGGGAGAACAAATGGTGGTCCGTCGACCACCTGAGGGACGACAAACCGCAAACCCCGATCCCGGACCCCACCGATCCGGACGGCATGAGGAAGGCGGTGGCCGAGGGCAAGGTCGAGCTGGTGGGCCAGGAGAAGATCGGCACCGTCGACACCCACCACCTCCGGGTGATCGGCCCCCGGCGCGAGTACAAGATCGACCTGTGGGTCGACAGCACGACGTACCTGCCGGTCAAGGAAACCGCAGTCAAGGCCGGCAACAAGCAGGGCGGTGACGAATTCCCGGAGTCCAAGGGCGAAGCGATCACCTACACCTGGCTGCCCCGGACAGAAGAGAATCTCGCCAAATTGACGCTGACCCCACCCGCCGACTTCAAACAGCTCAAGTAGACCCCAAGCAACAGCCCGCATGGACCCGGGCGAAGCCCTGCAGCTTCGAAGTGGCCCTTCAAGCGCGTCCGCGGCGCCAGCCCATCGGGCTGGCGCCGCGGCCGAGCCACCTCAGTCCGTGACCCTCCTCGGTCGTTTGTTCCCAGTCACGCTCAGCGGCATGTGAGTGGGTTTCAAGGGCCCCGAGTCCGGACCTGAAGGGCGTCGACTAGCGCCGTTCTCGGTGCGGATCATCGTGCTGCCGGTCCTCGATCAGCAGATCCGCTCGGCCGGAACGTCCACGTACCTCGTACCCGAGCTCGTGCATGCCAGTGGCGCATACGACGACTGGCTGCGCGAACTCGTACGCAAGCTTGCCTGAACGCATGGCGGCAGCAATCAAGCACCGGATCGTGCGGCGGCCAGACATGCGGCGCTACGCATCGATGTCTCGTTGATTCCCGGTCTGTCCTGCGCCGTGACGGCGCGGCCGGCGGCGGCGGCGCCGAACGTCCGCACAGCGGCACGAGAGTGATCGGGAATCTCGCGGCGGCTTCGACGTCGGCGAGGTTTGTACGCTGGGGGGATGGAGGCGGAACTGGCTCGCGAGCTGGAGCGGGTGGGGGCGGTCGCGCTGAGGACGACGGCGTGCGGCCTGGCCTGGGTGGTCGCGTTGGGGGTCCTCTGAGGTTCACCCCGAACGGTGGACAGGGGCTTACACAGTTCAAGCAACCACTGGCAGCGACTTCTCGTAGTCGTTGGGGCTGAGCATCCCGATCGAGGAGTGGCGCCGCCTACTGTTGTAGAAATTCAGCCATTTGTCAATCGCGGCAACGAGTTCCGTTTTCGTCGCGTAGACGTGCCGGTAGTATTCCTCATGTTTGAACGTCGACCAGAATGATTCCGCCGGGCTGTTGTCCCAGCAGATCCCGGTCTCGCCCATCGACCGGCGCAGCCCGTGACCGAAGCATGCCTGCGCCGTCACGTTCGCCGTGAACTCGCCGCCGCGGTCCGAATGCAGAATCGTGCCGCGGCACCCGCTGCCCCGGCCGGCCACCGCGTCGTCGATGGCGGCAGTGACCATCTCGGCGCTGATGTGGTCAGAAACGCTGTAGCCCAGCACTTTCCGGGAATGACCGTCCCGAATCGCACACAGGAACATGTCGCCCTCACCACACGTCAGATACGTGATGTCGGTCAGCCAGACCGCGTCGGTCCGGCCCCGGTCGAAGTGCCGGCCGACCAGGTCCGGCGGGAACGACGCGGCCGGATCGACCACCGTCGTGCGCACCTTGAACGTGCGCGGACTGATGCCCTCCAGCCCCACCCCGGCCATGATCTTGGCAACCGTCTTCGCCGTGACCACCTCGCCCTGGTCGCGAAGTTCCGCGGTGATACGCGGCGACCCGTAAGTGCCACCGGAGTCCTGGTGCGCCTGGGTGATCTTCACCTCCAGGTCGGCCCGGCGTTGCCGGCGCGGCGCCAGGACCGTTGCGGCGGCGCGTGTGGCGTGTGCGTAGTAGCCGGACCTCGACACATTCAGCAGTCGCGCCATGCGCCGGACCGAGAACCGACGTTCGTTCCGAAGTGGGACCCTGCCGGCAGTGTCGGCGGACTCGTCGGGGCCGGCGTACTTGGCCATCAGAGCGAACCGGGCCGGTTCTTCTGCATCGCGGCAAAGTACGCCGAGGCTTTTACCAGGAACGCGTTGTCCTTCTCCAGCTCGGCCACCTGCCCGCGCAGCCGCAGCAGCTCGGCCCGCTCGGCCGCCTCCAGAGGGTTCTCGCCGTGCACCTCGGCCGCGGTCACCCGGCGCCGCTCGTCCTTGACCCAGACACTCAGCATGCCCGCGTCGAGACCCAGCTCGCGGGCGACCTCCGCGATCGTCCGGCCGGAATCGATCACGCGGTGAGCAGCCTCGACCTTGTACTCCGCCGGGTACGACCGGCGCTTGCGAGGAGGCATGAGGACATCCTTCCAGCAGAACCCCTGGTCCTGCTAACTCGGTGTCCACTACCCGGGGTGAACCTCACTCCTGATCTCGTACCCCAGCGGCAGCGACATCGTGTCGTCCGTTGCGTTTGCAGTGATCGCGGCGTCGGTGTGCTTCACGCCGGGGGCGGTGCTGTGGTGGATGCGCTACGAGTCGGTCCGGCGCACCGGCTGGCGAGCCGTGACGGTCCAGGCGGTGATCGTGAGCGAACCGGCAGGGTGCCTCGCCGTCGCTCTCGCCGCGGTCCCCGGGCCATCGGTGGATCCCGAGCGGAAGCTCGACTACGTCGTCCGGTACCGCGACGGCGAAGGTGCTCGGCTGCGGGGTGGAGCCAGCTTGTGGCACCGCCCTCCGCTGTTGGCGTTCGATCGCGCGCAGCCTGGGTGGGTCGGTGGCACGGGCCGCTCGTGCGTCGTCCTGTTCGCCGGCGGGGGCTGGGGTCCCCGCCGTCCGCGTGCTGTGCCCGCGACGTTCCTCGCCGACCTTCCCGCACGCCCGCAGTAGCGGGCCGGGGCCACCGAGATCAGGGAGCGGGGTCGTGCCGCCGTCGTGGGAGCGAGGAGGCGTAGGCCGGTGATGTGGAGTCCGATCAGCATCGGCAGGTGTGGATCGAACTGAAGCCGCCACCGTGTGGTCGTTACCGACCGACGGCGACGCCGACATCCGCTCAGCAGCATGAGCGCGCGTCGGCCGAGAGGGTGAGGCACTGTTGAGGCACAATCGGGCCATGCCGTTGTTCGAGACTTTGTGACCGGGAGTACTCGACCGCCCGATTTGCGCAGCGGGCCTGTCCTTGTCCGGTGGGAAGCGGCCATTCGAGTGAGAACAGCCCATTGGAGTGTGAATCATTGTCCGAACGGTGATCTGATGTGGGACCGGCGAAACCGGCGGGGGCAGGGTGATGACGAAATCGACGGCAGCGGTTCACCGTACGATCGTCGTGGTCGACGTCGAGGGGTTCGGCGCGTGGCAACGGACGAATCACCACCAGCTCGCGGTCCGGCGCGGGCTCTACAGCTGCCTGCGGACCTCCTTCGACCGAGCCGGCATCCCTTGGGAATCCTGTGAAACGGAAGACCGCGGTGACGGCGTCTTCGTCCTCGCGCCGCCGGAAGTGCCGAAAAGTCTCTTCGTGGAGTCACTTCCCGCCCGGGTGGTGGACGCACTCGCGGAGCACAACCACCTGCACGGGCCCGAAGCCCGCATCAGGTTGCGGCTCGCGGTGCACGCAGGAGAAATCAACTACGACGACCACGGCGTCACAGCCGCGTCGGTGAACCTGACGTTTCGCCTCGCGAACTCGTCCGAGTTGAAGGCCGCGCTGGCAGGGTCGCGGGGCATACTCGCCCTCATCACGTCGAACTGGTTCTTCGACGAGGTGGTGCGGCACAGCATCGCCGCCAGGCCAGGCACTTACCGAAATGTGACTGTCTCAGCCAAAGAGACCGTCACTTCGGCGTGGATCGCCCTGCCCGACAACCCCTACAGCGACATCGTCGACCCAGCGAGACAACCGAGTCCCGCAGCAGGCGCCGAACGCCCTGTGCTCCCTATACCCCGGCATCTCCCGGCGAGCACCGCCCATTACACCGGCCGCCTCCCCGACATCGCCAAGCTCGACTCGTTGCTTGTCGAGCCCGGGGCGAGCGGGCCCGGCGAGACCACGATATTCCTGATCGTCGGCGCTGCCGGTATGGGTAAGACCGCGCTGGCCGTTCACTGGGCACACGCGGTGAGAAGCCAATTCACCGACGGCGACATCTACATCGATCTGCACGGCTACGACCCGGTCGCGCCCACACCGCTCGAGCAGATCCTGGAACGGGTGCTCAGAGCGCTGGGTGTCACCACCCGGAACATGCCGGCGGACCTCGAGGGACAGACGGCGCTCTACCGCTCACTGCTGGCCGACCGGCGTGTCCTGATCGTTCTCGACAACGCCGCCACACCAGAGCAAGTCCGCCCGTTGCTCCCCGGATCGGCCACGTGCCGGGTGCTCATCACCAGTCGCCACCGGATGTCCGGTCTGGTCGCCCGAGAGGGCGCCGCCCGGTTGACCCTCGATCCGCTCCACCCGACGGAGGCGTACTCCCTCCTCGGGCAGATCGTCGGTGAAGACCGGGTCGCGGTCGAGGGTGCCGCGGCTGCCGAGATCACGCGCGCATGCGCATACCTTCCGCTCGCGCTGCGCATCGCCGCCGAACGCGTCGCCGCGCACCCCAGACTCACCCTTGCCGAACTCGCTCGCCAGCTGTCCGGCGAACGCGACCGGCTCGACCTGTTGGCCGCGGACGACGACGAGAGCACGGCGGTGCGCGTCGTGTTCTCCTGGTCCTATCGGGCGCTGCCGCCGGCCGTTTCCCACGTGTTCCGCTTGCTCGGCTTGCACTCCGGCCCGGACATCTCGCTCCCGGCTGCCGCGGCGCTGACCAACCTCACCATCGAGCAAACTCAGCGCAATCTCGACGCTCTCGCCAGCGTGCATCTCGTGGAGGAGGTCGACCACAACCGCTACCGTCTCCACGACCTGCTTCGGTTGTACGCTGCGGAACGCGCCGGCGAGGACGAAACCGAAGCCGACCGCAGTGACGCCAAACTGCGTCTGCTGACCTGGTACCTGCATTCCGCCGACGCCGCCGACCGTCAACTCGCACCACGTCGGCGACATGCCCCGCTCGGCGAACCACCCGTCGGCTGCCGTCCTCTGACCTTCGAAACCCAGGGGCGCGCTTGGCAATGGTGCGAGGCGGAACGCCTCAACCTCGTCGCCGCGACTCGACAGGCCTCGGCCGAGGCGCACCTGGACATCGCTTGGCAACTCCCGACCGCGTTGTGGGGCTATTTCACCCTGCGGACTCCCTGGGTCGACTGGATCAGCGCCTACCGTATCGGGCTCGCCGCGGCCGAGCAGCAGGCCGACCGGAGCGGATACGCTTGGCTGCTCGCGGGTCTGGGAATCGCGTACCGCAACCTCCGCCGGTACGACGATGCGATCGACAGCTTCGAGCGCGCACTCGATGTCTGGCGCGAACTGGGCGACCGTTACGCCGAGGCGTGGACCCTGGGAAGTCTGAGCATCGCCCTGTGGGAGCTGGAGAGGTTCGCCGATGCCTTGGCCCGTTCCCAGGAGGCTCTCACCTTGTTTCGCACAGTGGACAGCCCGTACGGCGAGAGCCAGGCCCTGCACTGCTTCGGCGACGCCTGCCGCGGTCTCGGACGGTACGTCGAGGCGATTGACTATCTCCAACAGGCACTGCACTTGCGACGGGGGAGCGGCGACCCGGGCGGTGAATCCCAGATCCTCAAAAGCCTCGGGGACACCTACCGGGACCTCGACGAACTCGACAAGGCCGAAGAGCATTACCGGCAGGCGCTCGGGATGTGGCGTGAGGTCGGCGACCGCTGGAGCGAAGCGAGGAGCCTCACGGCGATCGGTGACATAGCGAAGATCCTCGGCAACCTCGACACGGCGGTTGAATGCTGGCGTCAGGCACTTGAGATCTGCGAGGAACTCGGTGCCCCACAGACCGCGGAGATCGACGCCCGGCTGAAACACGCGGCAAACGCATCTTCAGACAAGAGGCAATGAACTGACGAACCGGTCGTGTGGTTCGTCAGTGCGCGAAGTAAGGGGACTCGAACCCCTGACCCCCTCATTGCCAGTGAGGGTCGATCATCGTCCTGACCTGCGGTGATAGAGAATCGCCTAGTGAAATGATGGGCTTGACCGCCGTTGCTTGCAACGGTGTGTTGTTGAGTGCGGTTGTGACAGGGGGTTTGCCCCAGCTGCGTCCCAGCGAAAATTGGTGAGAGGAATGGCCGCGCTCGTCCGGACATCCAGTGCGGCCGACAGACGAGTCATGCCTGGATCCAGGCGAGCAACGTCGGACCCGGCTGAGTCGAGTAGCCGGAGCCCGCAGCCAAGCGGCGTCAGGTGTACGGCCCGCGCGCAGGCTGAGTTGTCGCTGAGCGTGGTCCGCCGGGATGCGCGCCGGCCGCCGCTCGAGGCCATGGCCACTGTCGAGCCTGGGAGCATCGCTCCTTGGGTGGCGGCTCGGCTGCACATCATGAAGAGCCAGGGTTGACAGTTGTAGACTACAACTCAATACTGGTGACATGGCCGCTCGGAACCAACTCGTCGACGCGCTGCACGAGGCGATCATCTTGTTCTCCCGCAACACGCGGGTGCGGGCGAACCAGATGTACGACGGGATGTCCTTCGTCGCGTACTCGGTGCTGTCCTATGTCGGAGGACGTCGGGATGCCACCGCATCGGGCCTGGCTGACTCCTACCACCTGGAGAAGTCCACGGTCAGTCGTCAGCTGTCCGAGTTGGAGGCCGCGGGCCTGCTGCGACGGTCCGCGAACACCGACCAACCCCGCACCAAGCGGTTGGAGTTGACCGCGGAAGGTCGACGTCGATTGCTCGATATTCGCGCTCATCAGCGAAATGGCCTCCAGGAGCGCCTCAGCTCCTGGTCCGATGAGGACGTCACCCGATTCGCTGAGCTCTTCGGTCGTTTCGTCCACGACCTCTGACCTTCGAGCGTTCCATCACCCACGCAAGGGAGCGTTGTCATGCCGCAGCCCGATCTTCGTCGTGCCCTCATTGAGGAGGAGCAGCGGATCGACGCCGAGATGGATCTCGAGGCGCACAATGCCAAGAGCCCCTACAACGTTGCCGGGTACCGGCCGGTGCGCAGGGAGCTGTCGCACTCACCGGTCCGCATCAGCGGCACTCTGCCGGCCGACCTCGACGGCGCGTACCTCCGCAACGGCACCAACACGCAGTTCGACGACTCCAAGGTCCGCCTGCACGCGTTCTCCGGCGCCGGCATGATCCATGAAATCCAGATCCGGGACGGCGCGGCCACCTACTCCAACTTCTACGTTCGCACGCCGCGGTTCGAAGCCGACCGCGCAGCGGGACGCGAGGTCTACGCCGAGTTCTCCGATCTGGTGGCCGGAAGGCCGGGTGCGCAGAGGTTGGAGCTGGTCGAGAAGAAGATCGAAGCCGGCATGGTGCCGCCGCTCGACCCGTTCGAACGCACCCCCGGCTCCACCTCGATCCGCTACCACCACGGCCGGCTCTACTGCCTGCAGGAGACCGGCTACGCGTTCGTGCTCAACACTCAGGTCGATGCCGATGGCCGGCTCGTGCTCGACGGCACCGGCACCCTGGAGACATGGGACGGCGAGTGGGAAGGCCCGTTCTCGGCCCACCCACGAATCGACCCGGACAGCCACGACGTCTACAACATCAGCGTGGAGCGTTCCGGCCGGATCATCGCGGGCCAGATCCATGAGGGTGAGCTCGTCGCCCAGGCCGAGGTACACCATCAGACCTCCGAGACCGGCTCGATGGGCTGGCTGCACGACTTCTTCCTCACGGCCGGTCATCTGGTGTTCCCCGACATCTCGGTCCGAGTTGCGCCCACTGGACTCACCGGCCCCGACGGCAGCCTGTTTCACCACGACGGCGAGTACCGGATGCGCTGGGGAGTGGTTCCCCGCGTCATCGACGAGAACGTGGGCGTCCAGTGGTTCGAGACGGACCACGTCGGCACCATCTGGCACGTCATCAACGGCTGGGAACAGACCGGGGAGGACGGTCACGCCCAGATCGTGCTGCACTCGCCCGTGTTCGCCGGCTATCCGGCCGGCATCCCGATCCACACCCCCGAGGAGCCCCCGGCTCAGGTCAAGACCTGGGTACTGGATCTCGACACCGGCAAGGTCGTCGACGACCGCCTTCTGCTCGACCACGGCTACGAGCGACCCAGCCTGAACCTGGACTACGTCGGCCGTCCCAGCCGCTACTGCTACCTGCTCGACGAGCACGGCGACGGATACATGGGGAAAGGCGTGCTGAAGTACGACCTCATCGACGAGAAGGAAGTCGCTTACCTCGACTACGGCGACATGTATGGCGGCGAGGCTCTGTTCGTTCCGCGTAGCGGCTCGACCGAGGAGGACGACGGATACCTTCTCGACCTGCTCATGGCCGCCGAGAGAGCCGAACTGATCATCATCGACGCTCGGACGATGATCGAGCTCGCTCGCCTGCACCTGCCCCAACGGGTGCCGTTCGGAGTGCACGCCACCTGGCTGACCACCGAAGAGATCGCCCGGCTGGCTTAGGCCGTCCGCGGTCGCCGTGCCGGCGGGCGCGGTGTAGACGGTCAGGTGCAGGCCGGGGTCGGCAGGCAGCTCCATCGACTCGACGTCCAGGTCGAGCCGGCCCACTACCGGCTGGTGCACACGCTTGCGTGCCGGTGGAGCCGAACGTCCTGAGATGCCCACCGCTGCCGATTGCGGCCGGCTTCCATGCGTGCCGGCGCGGCTGCTGCGCTCCATGCGCACGTAGTAGTCGACCGATACCCCTGCTGGTAGAGCTACCTCTTCGCGACGCAGGCCTTTGACCGGCGGTTGCCGCCGTAGGCGGGCAGCCTGGCCCGCTCGGGCGTGATCCGCGCGCGACTTCGCATGGATGCCCGAACCCACGACGAACGGAATGGCTGACCGATGCGTTCAGGGTGACGTTCCCTCATTTGTCCGTAGTGGACGTCCGGGTGTGGTCGGCGACGGTATCGAACGGCACCCCGTCGAGGCAGGGATCGTTCGGGTCGATGGCACGGACGACGCGGCGGCTGATGTCGCGTAGCTGACGCTGTTGGGTGTTGGTGAGGGTGTCGAACACGAGCCGCCGTACTTCGGCGACGTGTCCCGGTGCCGTGGCGACGACTTTGTCCCAGCCGGTGTCGGTCAGGATCGCCAGGGTGAAGCGCCCGTCGGTGGGATCGGGGGCGCGGCGGACCCAGCCGCGTTTCTCCAGCCGGGCGACGACCTGCGACAACCGCGCCAGTGAGCCCTCGGCGAAGGCGGCGAGCACGCTCATCCGCAGCGTGTGCTCGGGTGTCATCGACAGGCCGGCGAGTACCTGGTACTCGAAGTGGCTGATCTGCGCGTCGCGCTGGAGCTGTGCGTCGATGGCCACCGGGAGCCGTGCGAGCATCCCGGTCAGGGTGAGCCAGGTCTGCAGCTGCTCTTCGTCGAGCCAGCGCGGCTCCGCAACATCACTCATGCCCCCGAGGATAACTCGCCTGTGACCAAAGATGACTTGCATCTTTAAGTCATCGCGGCCTAGTGTCACTTAAAGCATTAAGTCATCGAGTGGCCGGAGGGCCTTGTGAACATCGTCTTGTGGATCATCGCCGGTCTGCTCGCCGCCGCTTTCGCCGCTGCTGGTGCGATGAAGCTGACGCAGCCGAAAGAGAAGCTCGCCGCGTCCGGCATGGCCTGGACCGAGGACGTCAGCCCCGGCCTGGTCAAGCTGATCGGCGGCCTGGAGGTCCTCGCCGCGATCGGCCTGATCCTGCCCGCCGTGCTCGACATCGCCCCCGTCCTGGTGCCGTTCGCCGCACTCGGCCTCGTCCTGATCATGATCGGCGCGATCGTGACCCACGCCCGTCGCAAGGAGACCCAGGCCATCGGCATCAACGTGGTCCTGCTGCTGCTCGCCGCCGTCGTCGTCTGGGGCCGGTTCGGCCCGTACTCCTTCGGCTCCTGAGCTGACATGTCACATCCGGCCATCCCGTAACGCCACATTCAAGGAGCACCTCATGCGCGCAATTCACGTCCCGGCCGCCGGCGAGCAGCCGCAGGTCGGTGACCTGCCCGTCCCCGCTGTTGCCGACGGCTCCGTGCTGATCCGGGTCAAGGCCGCTGCGCTGAACCCGGTCGACAACGCCATCGCCGCCGGCTACCTCGCCGGCATGCTGCCGCACGAGTACCCGCTGGTGCTCGGCCGTGACGCCGCCGGTGTCGTGGAGGCCGTCGGCGCCGGTGTCGAGCACGTCAAGCCGGGCGACGAGGTGTTCGGCCACGTGCTGCTCGCACCGCCGGTGCAGGCCGGCACCCTCGCCGAGTACGCCGTCCTGCCCGCTGCCGCGGTCGCGATCAAGCCCGCCGCCCTCTCGTTCGTCGAGGCTGCCGCGCTGCCGCTGGCCGCCGCGGCCGCCGTGCAGGCTGTCGACGCCATCGAGGCGAAGCCCGGGCAGACCGTTCTGGTCAACGGCGCGTCCGGCGGCGTCGGCTCCTACGCCGTGCAGTTGCTGGCCGCCGGCGGGGTCACCGTCATCGCCACCGGCAGCGACACCGGCCGGCTCACCGGTCTCGGCGCGACCACGGTGGTGGACCGGGCGGCCGGACCGATCGCCGAGCAGGTTCTCGCCGCCTACCCCGGCGGCGTCGACGCCGTGGTCAACCTGTTCGGGCACAGCGCCGATGACATCCCGCTCGCCGCCGTGCGCCGCGGCGGCAAGGTATCCGCCCTCACCCAGGTGCCCGAGGCCGACGCCGGTACCGCCGCGGGCGTCACCGTGACCCCGATCATGGCCGCGGCCGTCCGGGAAGTCACCGGACCGCTCGCCGAGCAGGCCGCCGCCGGCACCCTCAAGGTCGACGTCGGCTCGGTCATCACCCTCGACCAGGCCCTCGACGGGCTCGCCACCATCGCCGCCGGACACGCCAAGGGTAAGACCGTCGTCACTCTCGACAACTGATCACCAGCGCAAGACGGGTAGGGCTCCTCGCCCGCTGAGCCCTACCCGTCTCCCCGTCGCCAATCCCGCCCGCACGACTTGCCGAAGGATTCTTCATGACCACCAGCGCTCCCGCCACCAAAGCCGCCTGGAGTTCCACCCTCGCCGCCGCGGGAATCGGTGCCGTGGGCGGGTTGCTCGTCAACGCCGCCATCGCCTGGGCCGGTCAAGCCCTGCTCGGTGCCCCGGACGAGTTCCGGCAACTCACCCTGCCCGTCTACGGTCCGCTCACGATCATCGGCGCGCTGGCCGGCGCGATCGGCTGGCGCCTGATCGTCAACCGCAGCCGCAACGCCGCCCGCCTGCTGACCTGGCTCGTGCCCGCCGTCGTGGCGCTGTCCCTGATCCCCGACCTGATGCTGCTGTCCTCGAAGTCGCAGCCCGGCACCACCGTCGGCGGCGTCGTCGCTCTCATGCTCATGCACCTGGGGGTCGCCGCGGTGGCCGTTCCCGCCTACCGGCGGTTCATGCCGCCTCGCTCCTGACCGCAGCTCCTTCTCTCACCCCGAGGCGTGACCATGACGAACCGCAGCGTCCACGACCTGCTCAACCTGGCCAACCCGGCCGGTGCCTACGACGCGCTGCTGACCCGGGTGCTGCCGCAAGCGCGTGTCCAGCGCCGTTGGGAACCATCCGACGGGCCGCTGCCGTCGCTGTTCGTCAGCCACGGCGCCCCGCCCACCCTCGACGACCCGCAATGGCTCGACGACCTGTTCACCTGGGGACAGGCAATGCCCAAGCCCCGCGGGATCGTCATCGTCTCCGCCCACTGGGAGAACGCCCCCGCCGCGCTGTCCGGCTCGGCCGCCGGCACACCACTCTTCTACGACTTCGGCGGCTTCCACCCCCGCTACTACACCCTGCAGTACGCCACCCCGGACGCCACCGACCTAGCCCGCCGCATCGCCAGCACCATGTCCTCCACCGGACCTGTGCACCAGTTCACCGACCGCGGCCTCGACCATGGCGCCTTCATCCCGCTCATGGCGATGTACCCGGCCGCCGACGTGCCGGTCGTGCAACTGTCCATGCCCAGCCTCGACCCCCAAGCCCTGCTCAGACTGGGCCAGCGGCTGCGCCGGCTGCGCGAGGAAGGCATCCTCGTCATCGGCTCCGGGTTCATGACCCACAACTTCGCCGTCATGCGCAAACCCGCCCTCGTCGACTACACCATCGCCTTCGACACCTGGGCCGCCGACGCCATCAGCCGCGGCGACGTCGACACCCTCACCGACTACCGCGCCAAGGCACCCGGCGCCGACATCGCTCACCCCACCGCCGACCATTACGTACCGCTGCTGCTCACCCTCGGCGCCGCGACCGACCTGAGCACCGCGACCTCAGCCATCGAACGCATCCACTACGGCAACTCCATCCGCTCGATTCAGCTCGACTGACTCCGTGCGAAGCCTCAGCTCGCCCAGCGTGCCGGCGGGTAACCGCTTGCCGGTGCGCCGGCCGCTGACGGATTCTCCGGCCCGAACGTGGCGGCTGCCATGGCTCGCGCCGCTTCCTGGCCGTCGTTTCCGGGAGTCAGCGCGGTAGCGGGTCGCCGAGCGCCGTGACGGCACGGGACGGGCTGGGGCGGCCGAGTTTTGCGGCGAGCCAGATGCTGGTGTCGACCATCTTCTGCAGGTCGATACCCGTCTCGATGCCGAGGCCGTGCAGGTGCCACAGGAGGTCTTCGGTGGCGAGGTTCCCGGTGGCGCTGCCCGCGTAGGGGCAGCCGCCCAGGCCGCCGGCGCTGGCGTCGATCGTCGTGACGCCGTGGCCGAGCGCGGTGAAGGTGTTGGCCAGGGCTTGGCCGTAGGTGTCGTGGAAGTGCACGGCGATCGCGTCGACCGGGATTCCCGCAGCGGCCAAGGCGTCGAGCACGGCGACGACGCGGCCGGGTGTCGCGACCCCGATGGTGTCGCCCAGGCTGAGTTGGGTGCAACCGAGCGCCATCATCCTCGTGGCGACCTCGACCACGCGCTCGACAGGTACCTCGCCCTCCCACGGGTCGCCGAAGCACATGGACAGGTAGCCACGCACTCCAAGGCCCGCTTCGCGGGCGCGGGCAACGACCGGCGTGAACATCGCCAGGGATTCGTCGACCGTGCGGTTGAGGTTCCGCCTGGCGAACGTTTCGGTGACGCTGCCGAACACTGCGATGTCGCGCACGCCGGCCGCGAGCGCGCGCTCCAGGCCGCGCTCGTTGGGTACCAGGACGGGGTACCGCACTCCTGGTGCGAGGGTGATCGCGTCGAGGAGCTCTTCGGCATCGGCCAGCTGGGGAATCCACTTCGCGGGCACGAAGCTGGTCGTCTCGATGAGAGTGTGCCCGGCGTCGACCAATCGCGCGACGAATTCGGCCTTGACCTCGACCGGCAGCACGGCCTGCTCGTTCTGCAGCCCGTCCCGGGGGCCGACCTCGCAGATCGTCACCCGGGACGGCAGCCCGTGCAGCGGCGTTGTTCCGTAGTCCATGTCAGGCGTTCCTGATCGCGGCGGCTTCGCCGAGGTCGAGGATCCGGACGGACTTCTCCCGCATCTCGATCTTGCGGACCTTGCCGGTGACGGTCATCGGGAACTCGTCGACGACCAGGACGTAGCGCGGGATTTTGTAGTGCGCGAGCTTGCCGGTGGCGAAGGCCCGCAGGGTTTCGGCGGTCACCTCGGCCGCGTGATCGCGGAGCTTGACCCAGGCGCAGAGCTCCTCGCCGTACTTGACGTCGGGTACGCCGATGACCTGGGCGTCGACGATGTCGGGGTGAGTGTAAAGGAATTCTTCGATCTCGCGGGGGTAGATGTTTTCCCCGCCGCGGATGACCATGTCCTTGATCCGGCCGGTGATGTTGACGTAGCCGTCGGCGTCCATCACCGCGAGGTCGCCGGTGTGCATCCACCGGGCGGCGTCGATCGCCTCGGCGGTCTTCCCGGGGTCGTTCCAGTAGCCCAGCATGACCGAGTAGCCGCGGGTGCACAGTTCGCCCGCTTCGCCGCGGGGCACGGTCAGGCCGGTGGCCGGGTCGACCAGTTTGATCTCCAGGTGCGGGTGGACCCGCCCGACGGTCGAGACGCGCAGGTCGAGGGAGTCGTCCATGCGCGTCTGGGTCGAGACGGGGCTGGTTTCGGTCATGCCGTAGCAGATGGTGACTTGTTCCATGCCCATCCGGGACACGACCTGCTTCATCACCTCGACCGGGCACGGCGATCCGGCCATGATCCCGGTGCGCAGGCTGGAGAGGTCGTAGGCGGCGAATTTCGGGTGGTTGAGTTCGGCGATGAACAACATGGTCGGTACCCCGTAGAGCGAGGTGCACCGTTCTCGCTGCACCGCTTCGAGGGTCGCTTCGGGGTCGAAGCCCTGGGCGGGGATGACCATGGTGGCACCGTGGGAGGTGCAGGCCAGGTTGCCCATCACCATGCCGAAGCAGTGGTAGAACGGCACCGGGATGCAGACCCGGTCCGCCGGTGTGTAGCCGCAGAGTGCGCCGACGAAGTAGCCGTTGTTGAGGATGTTGTGGTGCGACAGGGTCGCGCCCTTGGGGAAGCCCGTCGTCCCCGAGGTGTACTGGATGTTGATCGGGTCATCGGGTGACAGCGCGGCCTGCGCCGCCGCCAGCCGGGCCGCGTCGCCGCACCGGCCGGCCGCGAGCAGTTCGTCCCATGCTCCCGACCCGATCAGCACCACCGAACGAAGCTCGGGACAGTTCCCGCGGACCTCTTCGATCATCCCGGCGTAGTCCGAGGTCTTGAACGCCCGTGCCGACACCAATACCGAGATCCCGGCCTGCTTCAGCACGTATTCGAGTTCGTGCGTGCGATAGCTCGGGTTGATGTTCACGAGGATGGCGCCGATCTTGGCTGTCGCGTATTGCAGCAGCGTCCATTCGGCCATGTTCGGTGCCCAGATTCCGACGCGGTCGCCCTTCACCACGCCGGTTTTCAGCAGACCCAGGGCGAGAGCGTCGACGTCGTCGCGCAGCTGCGCGTAGGTCCATCGTCGGTCCGTCGGGACCTCGACCAGCGCCTCCCGGTCCGGGTCCGCGGCGACGGTGCGGTCGAAATCGTCCCCGATGGTGTCGCCCAGCAAGGGCACCTCGGAGGGGCCGGAGGCGTAACTGCCGTTCACGCTCGACCTTCCGCCGGAGCGGGGACCACGGGGAGCACGACGCGGGAAAGCCGGGACGCGTCGTGGGCGATCACCTGCCGGGCCGGGCGCGACTGCGTGCCCAGGGGTTCGCCGGTGTTGAGGTTGCGGTCCCACCGGGGGAAGTTGCTGGAGGTGACGTGGACCCGGATGCGGTGCCCCGCGCGGAACACGTAGCTGGTGGACCACAGGTCGACGACCTGTTCGGTGAACTCGCCCGGCGTCGCCACCGCGCGGACGATGCCGTCGACGACGTTCCGGGAGACGCCGCGGGTGTCGACGTCGCAGAGCCGGACGACCCAGTCGGTCGTCGGCGCGTCGGTCGCCGCGGTGAGGTGGGCTCGGACGCGGCCGGTGACCTCGAGGTCGTCGGCGAGCGGGTCAGTCGTGTAGAGCAAGACGTCGGGCCGGGCTTCGATCTTGGCTTGGTCCAGGGGGCCGGGCGGGAACTCGTTGGACATCAGCAGGGCGCCGCCGGTGGTCGGCACCGGGTCGGCGGAGTCGTAGGTGAAGGCGCCGGTTTCTTCTTCGGTTTCCGGGGCGTCGAAGGCGAGCCGGTTGCCGGCGCGCAGGAACAGGTCGGTGTCGACGGCGCGGGCGAGGGGCCACTCCTGCTCCTCGCGCCACTGGTTGGTGCCCATGACGAACAGCAGGACCGGCGGCAGCTCGGGCTGCGAAGGTTCGTCGCCGGGGGAGAGCCACCGGCGGAGCCAGCCGAGTTCGAGGTCGGCGAATCGGCCGCGGAAGCCGAGGAGTTCGGTGCTGGCGGCCATCCCGAAGTTGACGTCGCCCAGGTATCCCATGGTGCCGGTGTGCGACCACGGGCCCATGATCAGGTTCGCGGGGCGGCCGGCCGCGCGCATCGCGGTGAAGTTGTCGAGGGTGCCCTGGCTGAAGATGTCGTACCAGCCGCCGGTGTGCAGGCTCGGCAGGTCGATCTCTGCCTGCCGGCCGGCGACGCGGCAGGAGTCGCTCCACTCCGGTTCCCGCCGGGACCGTTCGAAGCCGAGCTCGGGGATGCCGTGCCGTTCGAAGACGGGATGGTGGCCGGCGGGCAGCTCCCAGTAGGTGGTGTGCGCGACCGCGTCGGTGTCGCCGACCAGGGCCATGAGCGCCTGCCCCTGGGCCATCGGGTCGCCGGCGTACCGGCGGAGCAGCGTGTCCACGCCCTGCATGAGCGACCACGGCACGGTGATCCCGAGTTCTTGGGCCCCGCCGCGGGCGAAGAGCCCGTCGTCCGGCTCGGACCAAGTGACCATCGGCGAGATCGCCTTCAGCTCCGGCGGCTTGGCGAGCGCGGCCATCCACTGGGTGTTGCCCAGGTAGCTGGGCCCGAACATCCCGACGGACCCGTTCGAACCCGGGAGCGCCGCGGCCCAGCGGACGGTGTCGTAGCCGTCGTCCATCTCGTAGGTCCACGGCTCCCATTCGCCGTCGGAGGCGTAGCGACCCCGGGTGTCCTGGACGACGACGAGGAATCCGCGCCGCGCCCGGCCGACCGGGTCCATCAGGCCGGCCAGCATCGGCTGGTTCTTGCCGTAGGGCAGCCGGGCCAGCAGCACGGGCCACGGGCCGTCGGCCGTCGGCCGGTACACGTCGGCCCGCAGCACGACACCGTCGCGCATGGTGGCCGGCACGTCGTGTTCGATCGTCACGTCAAGCACAGGGGGCCTCGTTCCTCGCACCGATGAGAGCGACCGGACCCTGACAGACCGGCGAGACCCGCGGCACACCCGAACGGGTGTAGCGGCACGAACGCCGGTGCGGTGTCCTGAGCCGGGACCGTGACAGCAGCCTCCGGGGAAGTGTTTGATGTGGACATGCGGGTGCACTCGCTCCTCGAGCTGGAGGAGCAGTACGCGAACTTGCTCGCGGCGCTCGACCGTGGCGAGGCGTTGCGTCGCGCCCTGGCATTGCTCGCCGACGGTTCGGAAGTCGCGTGGACGGCCCGTCCGGACGCGGACGGCGTGCTGACGCTCGACCAGGTCACCGGCGACCGGACCGGCGTGCTCCGCGCCCTCCGGGTGCCGCCCAGCACGGGGCTGACCGGCAAGGTGTTCCGGGCCGGGCGCGCGGAGTGGGTCGACGACTACTTCGGCAGCCAGGAAATCACCCACGACTTCGATCGCCACATCGCCACCGAAAACGTGCGGCGCGTGCTGGCTGTCCCGCTGCTGCGCGACGGGGAGACGCTCGGGGTTCTCGCGATCGGCCCGCGGGAGGACGGAACGTTCGGCGACCGCGAGATCGAACACGCCTCGGCGATCGCGGCCCAGGCCGCGCTGGCGATCTCGCTCGCCGAACGCGCGCGGCTGAGCCGGGAGATCGCGGTTCACGAGGAGCGCCGGCGGATGGCGGCCGATCTGCACGACAGCGTCGGTGCGTTGCTGTTCGCCATCGGCTCGGGCATGGCCGATCTCGCCGAGTCCACCCAGGCCGATCCGGAACTGCGTGCTCGTCTCGAGGGGCTCCGGCGGCAGGCCGTGGACGCGACCACGGCGCTGCGCGAGTCGCTGCGCACGCTGCGCTCCTCGCCGGCCGCGCTCGCGCTCGGGGTCGCCTTGCGCGCCGACTGCGAGGCCTTCGCCGACCGCACCGGCCTTCCCGCCGAGCTCGTCATCCTCGACGAAGACCCGCCCGAACTCGCACCGTCCCGATCGGACACACTCCTCACCGCGGTCCGCGAAGCCCTGCTGAACGTTGAAAAACACGCCCACGCCAGCGCCGTCACCGTGTCGGTGCAGCACAGCAATCCCTGGCTCACCGTTGCCGTGCACGACGACGGCGTGGGACTCGGCCCGGACTACACGCCGGGTCTCGGTCTCACCAGCAGCGCCGAAGCGCTTGGCCGGCTGGGCGGTTCGGTCCGTGTCGTGTCCGATCCGGACGGTGGCACGATCTGGCGGGCCCGGTTGCCGTGCTGACTCGTGAGCGGACCCGGATCGTGATCGTGGACGACCACCCGGTCGTCCACGACGGCGTCGCGGCCCAGCTGCAGCGGTACCCGGACATGGTCGTCGTCGGCCACGCGGGCACCGGCGCGGAGGCGGTGACCGTCTGCGCCGCGGAACACCCCGACGTCGTGCTGCTCGACCTGCGGCTGCCCGACTGCCTCGCCGCCGACGTCGTGCCCGCACTGCACCGGGTCAGCCCGGACAGCCGCATCCTCTTGTTCACCGCGTTCCCGGAACACGTCGCCGTGGCACCGACCCTGGCCGCCGGCGCCTGCGGCATCCTGGTCAAACATGCCGGCGCCATTGCCATCCGTGATGCGATCCGCAGCGTCGTCCGCACCGGCGCCTTCCGAACCGGCACGCCCGCCTCGTCGACCGCACCGGTCACCGCCCGCGAGTACGACGTCCTGCGGCTCGTCGCGGCCGGGCACACCAACCCCGAGATCGGCACCGAGCTGAACCTGTCGATCAACACCGTCAAGACTTACCTGTGGACCGTGATGCAGAAACTCGCCGCCCGCAACCGAGCCCAGCTCATCGCCAACGCGCGCGGGCAGGGCCTGCTCTGACTCGTCCTTTGTGGACTAGCGGGCAACTGCCGGTGAAGACGGCTCCACTGCCGGACGGTCCGGTAGCGCAGTCGTTCCGTGCCTGGATCGCCATGCGCCGACCTGGCCAGCGATGAGTCCACGCAGGCGCGGTGGGCCTCAAGCGGCGAGTGCCAGGGGAGCGAGCGGGAAACGGTCCTCGAAAAGCGCCTGCAGAAGGCCGGGCAGCTCAGCGGGCAGGAGCTTGTCGCGGCAGGTCGAGACTGCGGCGGCTGACCAGCCGTCGTCGATCATCCAGGTTTTGTGGCTGTGTCGTAGGCCGTGGAAGGTGAGGCCGGGCTTGGCGGGTTGGAGGCGGATGGCGGGGTTGGGGATGTGGTGGTTGCCGTCGGCGGCGGGGCGGAAGGCTCGGCGGGAGAAGTTGCTGCGTCGGTGCCATTCGAGGTTGGGGGTGACGAAGACCTGGCGGTGGTTGTGGGTGGTCATGTGCCAGCGCAGGAGGCGGACGAGGAACGGGGGCAGGCTGATGGTTCGTTCGGACTCGTCGGTTTTGAGGTGGCTGAGGTAGAGCGGGCCGCTGCAAGGCTCGTGGAGCGCGCCGATGTCGGGGTCGAGGTAGATGGAGCCGGTGTCGTCGTCGTAGAGGTGGACGTTGTCGCGGTCGAGGCCGGTGAGTTCGCCCCAGCGGGCTCCGGTCCAGCCGCCAGTGACGATGAGGACTGCACCGCAGGGTCCGTACTTGAGGGCGACTTGGTCGGCGACGTGGAGGACTTCGGCGGGTTCGCCCCAGATCTTGCACGGGGTGCGCTGGGCGCGGCGGCGGCGGGCGACGAGGGGGTTTGCGGCGATCAGCTTCTCCGGTACGGCGTCGGAGAGCAGGAGTGAGAAGCATTTGATGATGCTGTCGACCGTGGTCTTGGCCAGCCCAGAGGCACGCAGCTTCTTCTCCCAGGTGCGGATGCCGAGGTTGGTGAGTTCGGAGAAGGTGGTGGTGCCCCAGCGGGGGAGGATGTGGATTTTGAGGAAGCTGCGGTAGTTCTCTTCGGTGCGTTGGTCGATGTCGAGGGAGTCGAGCCAGGCGGGGGCGAATTGGGCGATGGTGGTGCGGCCGTCTTCGGGGTCGATCCAGGTCCCGGTACGTTGTTCGTGGAGCATGGTGCTGATGTGGTCGTCGGCGGCGGTGGCGGTGGGGAAGCCGGAGATGGCGCCTTTGGTGCCGTCGGTGCGGCGGTAGCGGACTCGCCAGGTGTCGTCGCCGGCGGGTTCGGTCCAGGGCACGGTGAACTCCTGTGCTGTGGTGAGGGGGTCGCGTGGTGGTGCGTGTCCAGGACCGCTCCATAGGCGACAGAGGGGAAGCGTGTTCGGCGAAGAACCTCGTCGTGGTACCGGAACGGGTTTCAGTGACTGGTGCGGCGTCGGCGTCCGGGGCGACCGGTCTGGTCACGGTTGCTCGGTCCGCGGTGGCCTGCGGCGATGATCGCGCGGAGGTCGTCTTCGGTGAAGCGCAGGTGCTTGCCGACGAAGGTGCACGGGATGAGACGCTGGCCGGCTTTGCGGCGGAGCCAGGACTCGCCGACGGTCAGCCGCTCAGCCGCGGCTGCCGGCGTGTGGAGCAGCCGGCCTGCTTCATCGGTGGAGGAGTCGGCGGGCGGTAGTTCGAGCGCCACCGGGGCGGATCGCCGCAGGGCTTCATCGTCGGTCTGCATGGCTGCCTCGCAGTGAGCGACGGATCGTGGTCGCTGCTAACTCCGTCCAGCCGCATCGGAGGAGACAGGACTGCGGTGATGCGCGGCGAACCGCTTCGTGACGAGATTCGGCGAGGGAGCTGAGCTGCCGCCGATGGCATGAAGGTGCGCCCAAAGAACCTCTGGCGTCCACCTGTCCGAGGGACGCTGCTGGGGCACTTTTCGTGACCCCATTTCGCCGCCGTCGGCGCGGTGCCCCAGTTTTGCCCCAGCTACCCGCCGGTAGCTGAACTTCTTCTTGACGAAACTCAAGATCCGGTACAACGAAAAAACCGCCCTACCTGGATCTTCAAATCCGGTGGGCGGTGTTTCGTCACTGTGGAGCTAAGGGGACTCGAACCCCTGACCCCCTCACTGCCAGTGAGGTGCGCTACCAGCTGCGCCATAGCCCCGAGGCGAAGGTGAACTCCGCATCTCGTATGCCCACACATTACACCCCGCCCAGACCCCCTCCACGCGGGGGTCCCGGCAACGTCGTCAAGCGATCGACACCCCGCTCACCAGCATCTTCACACCTTATTTTTAGTCATGTATTGACCTCCGACTGTGGCCGCCGTTACATTTTGCGCGGTTGTGACGCCGAGGTCCCCGCCCGTTACGCCGCGTCTTCAAACCGGGCACACCTCTCGATGACGCCGCGCACGCGGCAGAGGAGGCTTCGATGACGAGACGGCGGGTGATGGCGCTGCTCGCGGCAGCGTCGGTTCTGGTCGGAAGCATGACGACGACAAGAGCTGAAGCCGCTGTTGCCCCGGACGGGTGGTACACCGTTGCCGCCGGGAACAGTGGGAAGTGCGTTGATGCCCGGGGCGCCGGGACAGCCGATGGGACCGTTGTCCAGCAGTACACCTGCAACCAGACCGCCTCGCAGCAGTGGCAGTTCCAGTCCACCGGGGACGGCTACTTCCGGATCAACGCCCGCACCAACCCGGCCGCCGCCTGGGACGTCACGAACGTCTCGACCGCCGATGGTGGCCTGCTCCAGCTCTGGACCTACGGAGGCGGCGCCAACCAGCAGTGGCAGGCCGTCGACGAAGGCGGCAACCGGTACCACTTCGTCAGCCGCAACAGTGGGAAGTGCCTCGACGTCCCCGGCGCCTCCACCGCCGATGTGCAGCTCCAGCAGTACACCTGCAACGGCACCGCCGCCCAGTCCTTCATGCTGACCCCCGTGAACACGAGCCAGCCGGGCCAGCCGGACTTCGGGCCGAACGTCGTGATCTTCGACCCGTCGATGCCGAGCTCGGCCATCCAAAGCCGGCTCGACAGCATCTTCGCCCAGCAGGAACGCAACCAGTTCGGCAGCCAGCGCTACGCCGTCATGTTCAAGCCCGGCACCTACGCCAACGACGTCAACGTCGGCTTCTACACGCAGGTACTGGGCCTCGGCCTGAGCCCCGACGCCGTCACGATCAACGGCGCCGTGCACGTCGAGGCCGACTGGTTCCCGCCGCAGAACGCCACCCAGAACTTCTGGCGCGGCGCCGAGAACCTGTCCGTGAACCCGAACGGGGGCGCCGACCGCTGGGCCGTCAGCCAGGCCGCGCCCTACCGCCGCATGCACGTCCGCGGTGACCTGCAGCTCGACGACGGCGGCTGGGCCAGCGGCGGCTGGATCTCCGACACGAAGATCGACGGCCAGGTCCGCTCCGGCTCGCAGCAGCAGTGGATCTCCCGCAACTCGCAGTTCGGCAGCTGGAACGGCTCGAACTGGAACATGGTCTTCGCCGGGGTCCAGGGCGCGCCCGCCAACACCTTCCCGGCGCCGCCCTACACGACCGTCGGCCAGACGCCGGTCGTGCGCGAAAAGCCCTTCCTCTACCTCGACAGCGCCGGGAACTACCAGGTGTTCGTCCCGAGTGTGAAGACCAACGCGGCCGGCACGACCTGGGCGAACGGCACCGCCCCGGGCACGTCGATCCCGATCGACCGGTTCTACATCGCCAAGCCCGGCGCCACCGCCGCCGACCTGAACGCCGCGCTCGCCGCGGGCAAGAACCTGCTGGTCACGCCCGGTGTCTACCACCTGAACCAGACGCTGCGCGTCACCCGTCCGGACACCGTCGTGCTCGGCCTCGGCATCGCCACGCTGACCCCGGACAACGGCCTCACCGCGATGACCGTCGACGACGTCGACGGCGTCAAGGTCGCCGGCCTGCTCATCGACGCCGGCACGACCAGCTCGGCCACGCTCATGCAGGTCGGCCCGGCAGGCTCGGCCGCGAACCACGCGGCGAACCCGACGTCGCTGCACGACGTCTTCTTCCGGATCGGCGGCGCCGCCGTCGGCAAGGCGGCCACCAGCCTGGTCGTCAACAGCAGCAACGTGATCGGCGACCACATGTGGATCTGGCGCGCCGACCACGCCGAGCGCAACGAATACGTCGGCTGGAGCACCAACACCGCCGACACCGGGCTCGTCGTCAACGGCAACGACGTCACGATGTACGGCCTCTTCGTCGAGCACTACCAGAAGACGCAGGTGGTCTGGAACGGCAACGGCGGCCGGACGTACTTCTTCCAGAACGAGATGCCCTACGACGTGCCGGACCAGGCGAGCTGGATGAACGGCTCGACGCCGGGCTTCTCCGCCTACAAGGTCGGCCCGAACGTCACCAGTCACGAGGCGTGGGGGCTGGGCAGCTACTGCTACTTCAGCACCAACCCGTCGGTCGCCAGCGCGCACGCGTACGAGGCGCCGAACACGCCGGGTGTCCGGTTCCACGACATGGTCACCGTCTCCCTCAACTACCAGGGCACGATCACGCACGTGATCAACAACACCGGTCCGGTGACGCCGTCCGGGACCAAGGCCGTCAACCTGGTGAGTTACCCCTGAGCACCGGCGTGCGCCGTGGTGGCGGCCGCGGCGCACGCCGGTCCTTTGTGGATACGCCCGAACGGGGTGTTCCGGGAGCCGGACGGGGTAATCCACGCGATACTGAGTGCTCCCAAAGCTGAATCCCTCGATCCGGGAGCGGCAGATGACCTCCTTCGCAGCGTTCACCGTCGTCGAACCCCGCAAAGCCTGGCCGCTGGTGGCCGTCCGCGGTGTGTTCGCCGTGCTCTTCGGGCTCTTCGCGCTGATCTGGCCCGGCGCCACCGTGCTCGTCCTGGCGATCCTGTACGGCGTGTACGCGATCGTCGACGGCATCGGCGGTCTGATGCAGGCGTTCCGCCCGGGCGACACCGGGCACCGGGTGGCCTACGGTGTCCTCGGTGCGCTCGGCATCGTCGCCGGGATCCTCGTCCTGGTCTGGCCCGGCATCACCGTCCTGCTGCTGGCCCTGCTGGTCGGCTTCTGGGCGATCATCACCGGCATCGCCGAGGTCGCCGCGGCGATCCGGCTGCGCAAGCAGATCCAGGGCGAGGCCTTCCTCATCCTGGCCGGCGCGATCTCGCTGATCGCGGGCATCCTCATCGTGATCAACCCGATCGCCGGCGCGTTCGGCATCGCGCTGCTCGTCGGCATCTACGCCCTCATCTACGGCATCGTGCTGCTGGTGCTGGCCTTCCGGCTGCGCAAGCTGGGAACAGCAGACGCGCAAAACTGAGTAACGTGCGGGGGTGTCGACCCGCGAACTGGTGGTGCTGGGCACCGCGAGCCAGGTGCCCACGCGCCACCGCAACCAGAACGGCTACCTCCTGCGCTGGGACGGCGAGGGCATCCTCTTCGACCCCGGCGAAGGCACCCAGCGGCAGATGCTGCGGGCCGGCGTGGCCGCCACGGACATCACGCGGATCTGCGTCACGCACTTCCACGGCGACCACAGCCTCGGCCTGTCGGGGGTGATCCAGCGGCTGTCGCTGGACAAGGTCGCCCACCCGGTCGACGCCCACTTCCCGGCGTCCGGCGCGCACTACTTCGAACGCATGCGGCACGCGACGGCCTTCTACGAGCAGGCCGACCTGCGGGAACACCCGATCGCCGAGGACGGCCCGATCGCGACCGGCAAGCTCACCCTCGAGGCCAGGCGCCTCAGCCATCCCGTCGAGGCGTTCGGCTACCGGCTGACCGAGCCCGACGGCCGCACCATGCTCCCCGAGCGGCTGCGCGAGCACGGCATCGCGGGCCCGGACGTCGGCCGGCTGCAGCGCGAAGGGCGCCTGGGGACCACCACGATCGAGGACGTCAGCACGCCGAGGCACGGTCAGCGGTTCGCGTTCGTGATGGACACCCGGCTGTGCGACGCGGTGTACGCCCTCAGCGAAAACGCCGACATGCTCGTGATCGAGTCGACGTTCCTGGCCGAGGACACCTCCCTGGCGAAAGACTTCGGCCACCTCACCGCGCAGCAGGCCGCCCGCGTCGCCGCCGAGTCCGGCGTCCGGCAGCTCGTCCTGACGCACTTCTCGCAGCGCTACCCCGATCCGGCGCGCTTCCTGGAAGAGGCGAAGGGCGAGTTCGACGGCGAGATCGTCGTGGCGCAGGACCTGGAGCGGGTCCAGGTGCCGAAACGGCGGTCTTTCCCAACGGCGTGAGAAGCGCCGTAGGCTGCATCTCGTGAGCCAGCCGATCCTGATGACCGTCGACGACGATCCCGCCGTGTCCCGCTCGGTCGCCCGTGACCTGCGCCGGCGCTACGGGAAGGACTACCGCGTCATCCGCGCCGACTCCGGCCCGGACGCCCTCGACGCGCTGCGCGAGATCAAGCTGCGCGGCGACGCCGTCGCGGCGATCCTCGCCGACTACCGGATGCCGCAGATGGACGGGATCGCCTTCCTCGAGAAGGCGATGGACCTGTTCCCGCACGCCCGCCGCGCCCTGCTGACCGCCTACGCCGACACCGACGCCGCGATCCAGGCGATCAACGTCGTCGACGTCGACCACTACCTGCTCAAGCCGTGGGACCCGCCGGAGGAGAAGCTCTACCCGGTGATCGACGCGCTGGTCGAGACCTGGAAAGCGGTCGGCGACAAGCCGGTCGAAGAGGTCAAGCTCATCGGCCACCGCTACAACTCGCCCTCGTTCCACCTGCGCGACTTCCTCGCGCGCAACGCCGTCCCGTACCGCTGGTACTCGGTCGACGACGACGAGGGCGGCCGGATCCTGCAGGCCGCCGAGGCGACCGACAAGGACATCCCGGTGGTCGTCACGCCGGACGGCACCGTCCTCAAGAACCCGACCGGCAGCGAGATCGCCGACGCGGTCGGGTTGTCGACCCGGCCGGCGCAGGAGTTCTACGACCTCGTCGTCATCGGCGGCGGCCCGGCCGGCCTCGGTGCCGCGGTGTACGGCGCCTCCGAAGGCCTGCGCACGGTGCTCGTCGAGAAGAAGGCCACCGGCGGCCAGGCCGGCACCAGCTCGCGCATCGAGAACTACCTCGGCTTCCCCGACGGCGTCTCCGGCGCGCAGCTGACCGACCGCGCCCGGCGCCAGGCCCAGAAGTTCGGCGCCGAGGTGCTGACCGCCCGCGACGTCGTCGGTCTCCAGGCCCGCGGTTCGCAGCGGGTGATCACCTTCGGTGACGGCAGTGAGATCGCGGCGCACTCGGTGATCCTGGCCAGCGGCGTCAACTACCGCGCCCTGGAGGCCGACGGCATCGAGGAGCTGAGCGGCCGCGGCGTCTACTACGGCTCGGCCGCGACCGAGGCGCCCGAGTGCAAGGGCGAGCACGTCTACATCGTCGGCGGCGCCAACTCCGCCGGGCAGGCCGCGGTGTTCTTCTCCCGCCACGCCAGCGACGTCACGATCCTGGTGCGCGGTGCGTCGCTGGAGTCCTCGATGTCGCACTACCTGATCGAGCAGATCGCCGGGATCGAGAACATCCACGTCCGCACGCACACCACCGTCAAGGAGGTGCACGGCGACGGCCACCTCGAGCGGCTCACGCTGTGCGAGAACGGCGTCACCGAGACGGTCGACACCGGGCACCTGTTCATCTTCATCGGCGCCGCCCCGCGCACCGACTGGCTCGGCGACGCCATCCACCGCGACGAGCACGGGTTCGTGTGCACCGGGCCGGACCTGCTGAGCGCCGGGCAGCGGCCGGCGGGCTGGCCGCTCGACCGTGATCCGCACTACCTCGAGTCGTCGATCCCGGGCGTGTTCGTGGCCGGTGACGTGCGGTCGCAGTCGGTCAAGCGGGTGGCCTCCGCGGTCGGCGAGGGCGCGATGGCCGTGACGCTGGTACACCGGTACCTGGAGGAACAATGAGCGCACTGCCGCGGGAAGAGCTTCGCGGCCTCTTCCTGTTCGAACACCTTTCCGAAGCCCAGCTCGACTGGGTCGCCGCCAACGGCGTGATCGAGGAGTACGAAGGCGACACGTTCGTCATCCGCGAGGGCGACGAGGCGACCTGCTTCTACGTGATCCTGAACGGCGCCGTCCGGATGACGCGGCTGGTCAGCGGCACCGAAGTCGAGACCAACCGGTCCGACCAGCGCGGCGCCTACTTCGGCGCGACGCAGTTCTTCGTGCACCAGGACGCCGAGCACCGCTACGGCGCTTCGGTGCAGGCGCTGAGCGACCTGACGCTGCTGGCGCTGCCGTCGAAGGAGTTCTCCACCGAGTTCCGCAGGTGGTTCCCGATGGCGACGCACCTGCTGGAAGGCATGTACCTCGGCTGGCGCAACAGCGACACGGTGATCGGCTCCCGCCGTCGCCTGCTGGCGCTCGGCGAGCTCTCGGCCGGCCTGACGCACGAGCTGAACAACCCGGCCGCGGCCGCCGTCCGGGCGACGTCCGCCCTGCGCGAACGCGTCGCCGGGATGCGGCACAAGCTCGCCTTCCTGGCCAAGAAGGACATCGACCCGGAGCTGCTCTACCAGCTCATCGACGTCCAGGAACGCCTGGTCAAGCAGGTCGTGCAGGCCGAGAAGCTGACGGCGATGCAGCAGTCCGACCGCGAGGACGAGATCGGCGACTGGTTCGACGACCGCGGCATCGACGGCGGCTGGGACCTCGCCGACATCTACGTCCGCGCCGGGCTGACCACCGCCGACCTGGACAACGTCCTGGAGCAGGTGGGCGACACCTTCATCGACGGCGCCGTTCGCTGGCTCGCCTACGCGCTCGAAACCGAGATGCTGATGGGCGAGATCGAGGACTCCACGACCCGGATCTCCGCGCTGGTCGGCAAGGCCAAGCAGTACTCGCAGATGGACCGGGCGCCGCACCAGTGGGTCGACGTCCACGACGGCCTCGACTCCACGCTCGTGATGCTGTCGGGCAAGATCGGCGGCGGCATCCGCGTCGTCAAGGAGTACGACCGCAGCCTGCCGAAGATCCCGGCGTACCCGGCCGAGCTGAACCAGGTCTGGACGAACATCATCGACAACGCCCTCGGCGCGATGAAGGGCGAGGGCACGCTGAGGCTGCGGACGTGGCGCGTCGACGACCAGATCCGCGTCGAAATCGGCGACACCGGCCCGGGCATCCCCGCGGACATCAAGCCGCGGATCTTCGAGCCGTTCTTCACGACCAAGCCGGTCGGCGAGGGCACCGGGCTGGGCCTGGACATCTCGTGGAAGATCGTCGTCGAACGGCACCAGGGCGACCTGCGCGTCGAATCCGAGCCGGGGAACACCCGGTTCGAGGTCTGCCTGCCGACGGTCGAGCAGGCCTCGCTCTGATGGCTTCCGTCCCGACGGTCACGACCGAACTCGGGGCGCTGGTCGGGCAGGCGGGCGACGGCGTCCGCGTCTGGCGCGGGATCCCGTACGCCCGTCCGCCGGTCGGTGAGCTGCGGTGGAAGGCCCCGCAGCCGCCGTCGCTGTCCGGCGGCGTGCACGTGGCGACCGAGTACGGGCCGCACGCGATGCAGTCGCCGGACCCGATGAACCCGGCCGCCGTGTGCGACGAGGACTGCCTGTACCTCAACGTCTGCACGCCGGAGGGACCCGCGCCCGAGGGCGGGTGGCCGGTGCTGTTCTGGCTGCACGGCGGCGGCTACCGCGTCGGCCACGGCGAGCAGCTGGGCGACGGCGAGGAGTTCGCGCGCGCCGGGATCGTCGTGGTCACCATCAACTACCGGCTCGGCTCGCTCGGCTTCCTGCACCTCGCCGGGATCTTCGGCGAGTCCGAAGTGGACGCCGGGGTCTGCGGGTTCCTCGACCAGGTCGAGGCCTTGAAGTGGGTGCGCCGCAACGTCTCCGCGTTCGGCGGGGACCCAGAGCGGATCACCGTCTACGGCGTCTCGGCGGGCGCGAAGAGCGTCGGGAACCTGCTGGGCAGCCCGCTGGGCGCGGGGTTGTTCGACCAGGCCATCAGCAGTTCCGGCGGCGCGGACCACGTGGCGACGCCGGAGGCCGGGACCGCGCTGGCGCGGCGGCTGCTGGACGAGGTCGGCTGCCAGGACCTCGCCGCCTTGCGGTCGCTGCCGGCCAAGGAGTTCGTCGAAGCGCAAGAACGGATCCTGAGCGGCTTCCAGGCGCTGTGGCTCTGGCGGCCGACGCTGCACCCGCGCGTGCTGCCCGAGGTGCCGATCGGGCCGATCCGGCGGGGGAGCGCGGCGGGGATCCCGCTGCTGGTCGGCTGCAACAGCAACGAAGGCAGCACGTACGCGATGATGCTCGGCGACGACGTCGCCACGGCGCCGGCTTCCGGTGTGCTCACGAACATCCTCGGCGACGCAGGGGCGTCACAGCTTCTCGAGACGTACCTTCGGCGCGTTCCCGACCTGAAGGCCGCTCGGATCGCCGCGCTGGGCGACGAGCGCTACGGCATTCCGACGCAGCGGCTCGCCGACGCGCAGTCCGCGCACGCTCCCGTTTACCGGTACCGGATCGACATCGCCGCGCCCGGCGTGCCCGAGCAGCTCGACGGCGGCCACGGCACCGAAACCACGATGGCGTGGAAGGTCCCGCTGCCCTTGGCCGCGCAGGGGACCGCCGTGAACCCGGCGCGCGAGCGGGCGGCGCTGCTCGTCCACCGCGCCTGGGTGCGGTTCATCCGCGACGGCGTCGCCGACGCGGACGGTCCCGAATGGCCACCCTACGGCCCGGAACTGCGCCCGGTGCTGGTTTTCCGGGAAGACACCGATCTGGTGCTCGATCCACGCGCCGACGAGCGGAAAGCCTGGGGCGACACGGAATGGGCGTCCGGGACCTGGTTCCCGGTGACCTGAGACCGTTCATTCACCCGCCGTTCACTTCGAACCGGCTCGCTCCCGCGTCCAATGAGCGAAAGCCCGTCGAGGGGAGTGGCCGAGTGAAACGCCGGGTGTCGATCGGACTGGCCGTGGTGCTGGTGCTGGCCGTCGTGGGGGTGATCATCTGGGGTCGCGGTGACGACAGTGCCGCGGGCTCCACGACGACGGTGCGCGGGGTGATCGGTTCGGAGAAGCAGGCCTTCTTCACCGACCAGCGCGTCGTCGACGCCTTCGCGCGCCACGGCCTGAAGGTCGAAGTGGACACCGCGGGCTCGCGGCAGATCGCGACGACCGTCGACCTCGGCAAGTACGCGTTCGCGTTCCCCTCGTCCTCACCCGCGGCGCAGAAGATCCAGCGCGACCGCAAGGTGACGACGGTCTACACGCCGTTCCAGTCGCCGATGGCCGTCGCCTCGTTCGAGCCGATCGTTTCCCTGTTGCGGGCCAACGGGACCGTGCACAAGGGGGCAGGCGACTACGATGTCCTCGACATCGCGAAGTACCTGGACCTGACGAAGGCCGGGACGCGCTGGGACCAGCTGCCGGGCAACACCGCCTATCCGGCGCGCAAGAACGTCCTGGTCACCACGACCGACCCGCGCGAGTCGAACTCCGCGGCGATGTACCTGTCGATCGTTTCCTTCGTGGCCAACGGGAACGCCGTCGTCAGCACGCCCGACCAGGAGGCGAAGGTGCTGCCGTCGGTGGCGAAGCTGTTCCTCGACCAGGGGTACACGCAGAACAGCACCGAAGGGCCGTTCGAGGACTACCTCTCGGCCGGCATGGGCAAGACGCCGCTGGCGCTGATCTACGAGTCGCAGTACGTCGGCCGCGTGCTGAGCGGCGACGGCTCGATCCGGCCGGACATGCGGATGCTCTACACCGCGCCGACGGTGTACTCGAAGCACACGCTGGTGCCGTTGACCGGCGACGGCGACAAGGTCGGGCAGCTCCTCGCGACCGACCCCGAGCTGGGCAGGCTCGCCGCGACCTTCGGCTTCCGCACGACCGACCCGAAGCTGTTCGCCGAGGTCGCCGCGTCGGCCCACCCGCCGGCCGACCTCGTGGACGCCGTCGAACCGCCGTCGTTCGAAACGCTCGAGCGGCTGCTCGACGCCGTCGGCAAGCAGTACTGACATGGACTTCGCGCTCACCCCGCCCGAGCCGGTCACCGCGATCCCTTCCGAACGCGCGGCCGGGCTGATCACGCTCAGCGAGGACACGCGGTCGGCAGTCTCCGTTCGCGCTTCGGAGTTCGCGTCCCGGCTCGAAGCCCTCGACGTCCGGTCGCCGGAGTTCACCGACCTGCTCGACGAGCTGCTGACCGTCGGCGAGGCCGACATGCGCGCGGCGGCCGGGGTCGCCGGAACGATGCTCGACCGGTCGTTGCGCAGTGCGGCGTCCCCCCAGGACGGCGTCACGACGAGCCTCGCGAGCCTGCGCCGGACGGTCGCCGAGCTGGACCCGGCGAAGCTGCCGCTCACCGGCCGGAAGCTGCTGGGGGTGTTCCCGGTCGCGGCCGGCGCGAAGCGGGCGCTGGATCGCTACCGCGCGGCGAACGAGCCGGTCAACGCCCTGGTCGTCGACCTGCGCGGCCGCCAGGACGTCCTGCGCCGCGACAACGCCTCGATCAAGGGCGAGCGCGAGCGGTTGTGGAAGGTGATGGGGAAGCTCGCCGAGGCGGCCGCCCTTGCCGAGGCCGTCGACGGCGCGATCGAAGCACAGGCGGGCGTCTTCGACCTGACGGATCCCGCGCGCGCCAACGCGTTGCGCGCGGACGTGCTGTACCCGATCCGGCAACGGCACCAGGACCTGCTGACCCAGCTCGCCGTCAGCGCGCAGGGCTACCTCGCGCTGGACCTGGTGCGCAAGAACAACGACGAGCTGATCCGCGGTGTCGAACGGGCGGTGTCGACGACCGTGTCCGCACTGCGGGTCGCGTTGCTGGTCAGCGGGGCGCTGGCGAGCCAGCGGGACGTCCTCGACGAGGTCGCGGCCCTCCAGGCGACCACCGACGGGCTGATCCGCGCGAACACCGAGCTGCTGGACCTGCAGTCCGCGGAGATCCGCCGGGCGAGCAGCGACCCGGCCGTCGCGACCGAGACGATCCGGCAGTCCTTCGATCGGATCTACGCCTCGATCGACGCGATCGACGGGTTCCGCGCCGACGCCGTCCGCACGATGGCCACGACCGTCGAGTCGCTGTCCGGCGAGATCCGCCGCGCCGAAGACCACCTGCGACGCTCGCACGAGGGGGAAGCATGAGAAAACTCTGGGGGCTCGCGCTCGCTGCCTTGCTGCTGGCGGGGTGTTCCGATCCGGCGGCCGCGCCGCAAAGCGAGTCCGCGCCCGAACCGGGGACGCTGCGGATCCTCGCGGGCAGCGAGCTGGCGGACATGCAGCCGGTGCTCGACGAAGCCGCGCAAGCCACCGGGGTGAAGGTGAAGTTCACCTTCACCGGCACCTTGGAAGGCGCCGAAGCGCTGGCGAACGGCAGCGCCGACGGCAAGTACGACGCCGTGTGGTTCTCGTCGAACCGCTATCCCGCCGGCCTTCCCGAAGCGGCGAAACGGCTCGGCAACCAGGTCAAGATCATGAGCTCGCCGGTGGTGCTGGGCCTGGCCACGCCGGTGGTGCAGCGGCTGGGCTGGGCCGGCAAGCCGGTCAGCTGGGGTGAGATCGCCGCGCAGGCCGGGAAGAAGGCGTTCAGCTACGGGATGACGGACCCGTCGGCGTCGAACTCCGGGTTCTCGGCGCTGGTCGGGGTCGCGTCGGCGCTGGCGGGCGCGGGCAACGCGATCGACGCCCGGCAGATCGCTTCGGTCACTCCGCAGCTGACGCAGTTCTTCAGCGCCCAAACGCTTTCGGCGGGGTCTTCGGGCTGGTTGTCGGACGCGTACGTCCGGCGCGCGACCGGGCCGGACGCGGTCGACGGGCTGATCAACTACGAGTCCGTGCTGCTGTCGGCGAACGCGTCCGGGAAGCTGCCCCAGCCGCTCACCCTGGTCTACCCGAGCGACGGGGTCGTCACCGCCGACTACCCGCTCACCCTGCTGGCGGACGCCGGTTCCGACGCGCGCTCGGCCCACCAGCGGCTCGCGGACCACCTGCGGACGCCGGCGGTGCAGAAGCGGATCATGGAGACCACGCAACGGCGTCCGGTCGTGCCCGGGGTCGCGCTGGGGCCGCAGTTCGCGCAGCGAGACCTCGTCGAACTGCCGTTCCCGGCGACGCAGCAGGCGGTCGACGCGTTGCTGTCGGCCTACTTCGACAAGCTCCGGCGTCCCTCGCGGACGCTTTACGTGCTCGACACGTCCGGCTCGATGGCGGGCGCGCGGATCGACTCGCTGCGGTCCGCACTGGTCGGGCTGACCGGCGCGGACACCTCCTTGACCGGCCGGTTCCGGCGGTTCCGGAGCCGGGAGGAGGTGACGATGCTGCCGTTCAACACCGGGCCCGGGGCACCGCGGACGTTCACCGTGCCGGAGGAGAACCCGGCGGCCGAACTGGCGCAGATCAAGACGTTCGCCGAAGGACTGGTTGCCCGGGGCGGAACGGCGATCTACGACAGCCTTTCCCGGGCGTACCAGGTGCTCGAGCCGCTGATGGCCGCGGACCCGGACCGGTTCACCTCCATCGTGCTGATGACCGACGGCGAGAACGCGAACGGCTCGTCACTGCCGGACTTCCTGACGTCGCTGGCGTCGCTGCCGCCCGCGATGAAGCAGGTTCCGGTGTTCACGGTCCTGTTCGGGGAAGGCAGCAGCGACGAGCTGACCCAGGTCGCGACGCGGACCGGCGGCAAGGTGTTCGACGCGCGCAACGTCCAGCTGTCCCGGGTGTTCCAGGAGATTCGCGGGTACCAATGATGCTGCGTTATCTGGGCTCGACCAAGAACCTCGCCGGCTGCGTCGGCGGCCTGCTCGGCGTCGGGCTGTACCTGATCGGGGTGGTCGGGTGGTTCTGGCCGTTCGTCGTGGTGGCGCTCTACGCCGCGGGAGCGCTGCTCGCGCCGGGGGAGAAGGTGCGGCTGGTACCCGATGCGTCCGCCGGGCTGCGGGAGTCGCTGGACGCGCTCGAGGCCACGGTTTCCGCGCAGGCGTCCCGGATGCCGCCGTCCTCTGTGGACACTGTGCACCGGATCGCCGAGGTGCTTCGCGACCTGCTTTCCCGGCCTCGGCGGCTCTCGGGTGACCCCGAGCTGCAGCACGCCGTCGTCCGGCTCGCGGGCACGGATTTGCCGCTGTCGCTGGAAACCTACCTCAACCTACCGCGGTGGTTCGCGGCGCGGCGTGCCGGTGCGGGCTCGGAATTGGTGACCCAGCTGGGTTTGCTCGAGGCGGAGGCGCACCGGGTGGCCGAACGGTTCTACGCGACGGAGGTCGACCGGCAGGCCGATCACACGCGGTATCTGCGGGATCGGGAAACCTGAACCCCTGTGGGTGACGACGTTCGAACGCGCGTTCGAGTAGTGTGGTCGATGTCTCACAGGGAAGGGGAAATCATGAACGCGTACCGAGGTTCGGCAGAGTCAGCGTCATCGCGGCGGTGGTCAGCCAGCTCAGCAGGTCCGGCAGGGGAATGCGGGAGAGGCGGTCCGGCCATTCCTCCGCCACTGTGTGCAGCACGAGCTCGTCGTGCCGCGGCTCCACCTTCGTCAGGTTCAGGCCGGGCGGAAGTTCCGGCAGGGGAAGCACGATGGGCCGGAAGCGGCGGGGCGGCCGCAGCTGCCGCTGTCCGATGTGGAGGGTCTGCGGCACGAGCACCACACCGTCGGCCGCCACCTGCGGGCGGAGCGTCAGGTGGCCCCAGTGCGGTCGCTTGGCCCAGTGGATCCGCAGCAGGCCGCCGTCGGCCGGAGTCGCGACGATCCCGGGGCGGGCTTTCGCCACCCGGTCCTGCAGCACCTCGGCGGAGACGGCGATCGCCAGCTGCACCCGCGCGGGTTTGGCGGCCGGCGTGGGCAGCGAGCGGAGGCGGACGTCTTCGGCGAAAACGGTGACGCGGCGCAGCGGGATGGTTCCGGGCTCGCCGTCGTCTTCGGGCTCTGGCCAATCGACGTCCTCGGCGACGATCCGGACGTCGCCGAGGCGTCCGGTGGCCAGCCGCAGGCTGTCGGCCGGGTAGTCGAGTTCGGCGAGGGTGAGGCCGACCTCGCGGCCACCCACCTGCGCGGTCAGCCGCCGGCCGACGAGCTGTTCGGTGACGGTGCGCACCAGGGCGGCCGGCGTGACCGGGACGTTCGGCAGGAGCGAACGCCCGGCCGCGGCCAAGCCGGCCAGCTCGGGCCAGGGTGACCAGCCGTCGAACCACCTGCCGTCGCTCATCCGCCCAGTGTCGCCCACGGACACCGGCGGCGGCGACGGCGGGTGGTTCCCGGCCGGCCCAGCGGATCGCCTCCGGTCACCGTCCCGCGAAGCGGGCGATGATGCCGGTCACGACCAGCCAGAACACCGCGGCCAGGCCGAAGTCGAGGATCACCTGCAGGTTGCCGTCGCCGACCGGGAACAGGCCGGGCCAGAACAGGGCGAGAGGAACCGCCAGTGACTTGATGAACTGGAAGAAGGAGTTACCGGCGTTGGCACCGGCCAGCACCATGATCATGTAAAGAACTTCGATCCCCGCGAAGATCGCGCCGATCGCCGTGATGACCCGCACGGCCGTGTTCCGTCTGGTGGTGGTTTGCCAAGGAGACATGCCGCGAAAATTCCCGGATCAGGTGACGGATCAAACGCTCCAAGGCCCAGATTGCGCCGTTTGGCCGCTTCTCTTGCTCTCCGTCAGTACTCCGGCACAAGTGGTGAGCGACTGAGGTCCGGTGTCGGCGCGCTTGTCCTTTTTCGTCGTCTCTGCTCAAGGAGCTGTGGTCATCAGGTTCGTCCGCTGCCCAATAACGAACCCCGGCTGCGGGCGTTGTTCGACAGGCTCACTCAGCACGGAACGCTGCCAGCCGCGGTGAACCAGTCGGCCATGGCCGGGCATCGCCGCTCCCGTTCGCCCGCACTGCGGCACATCGCCGTTCGCTACTCCGGCCGGCTAGAGATCGACGCGTCGGCTTCGACGATCCCCGGCGGCGAGGCCATCAGCAGCCACACCCGGGGCATCTGCTCCGGCATCCACCCGGCGATCGAGCACGCCATCGCCCGCAGATCAGCCACCCGGCCGTTGTGGAAACTCACTCCTGCTGCGGCGGCTCGGACGGCATCGCCAAGGCCGGTCGGCAGCCTGAAAACCGTTCTCCAGCAATACAACAAGGTCATCCGCGCACCTGGCCGCTCACACAGGCATCACTCGCCCGCACCGCTGCAACCCGTGCCACGCCCACAACGGCACCCCACGCCCGCCGCGGCTAGACATCACACGGACCCGCCCCGGTGCACAGGCTCTCCGCCTGAGTAGCTGTGTCATCGGCCCCTACTCGCCGCGTCACCGAGCAGCCGGGCGACGGCCCAGTCCTGCACAGCGAGCCCGACGGACTTGAACACGGTCCGCCCACTGACCACCGGAGGCGTGCGCAAGGCCGCCCCGAGCTCGATCAGGTCACCACGGTCGAGGACTCCGCTCTCCACCGCATGGATCACCTCGCCAGCCTCCTCAAGAGCGGCGTCGACCTGATCCACCACCACGCACCCCGCGGTGGCGAGCAGTTCGGCGGGCAGCTCCCGCATGGACGGCAGGTACGACCCGATCGCGTTGACATGAACCCGGTCCGGCAAGTCATCGACAGCGAAGAGAGGAGTACTGGACGAAGTAGCGCAACAGACGATCTCCGCGTCGGACACCGCGTCCGGGGCGCTCGAAGCCACCCGAATCGCCACCGATGGGAACTCGGCACTCAACCGGCCCGCCAACGCCTCCGCACGCGAGAGGTCGCGCCCGAACACCGTTACGCGGCGCATCGGACGCACCGCCGCCACCGCGCGCACCTGGTCGGCGGCCTGGGCTCCGGTGCCGAGGAGTGCCAGGCTGCTGGCCTCGGCCGGGGCGAGCAGGTCCGTGGCGACGCCGGACACCGCGCCGGTGCGCAGGGTGGTGACCTCGACGGCGTCGGCGACCACCTGGCCGTCGGCGGTGTTCCACACCAGCGTGCCCAGGATCATCGGTGCCCGGCCGGGGACCAGGTTGAGCGTCTTCACGACCGTCGTCGACGTCGGTGTGTGGCAGGCGGTCATCACGAGCGTCGTGGCTCCGGCGAAGGACAGCCGTTGCGGCACCACGAAACGGCCGGCGGCGAGGTCGAGGAATGCCTCGCGGACCGCTTCGACGGCGGCCGGCATCGGGACGGCCCTCCGGACATCGTCGGCGTCGAGCATGCGCGGCCCCTCCGGCGTCGGAACTGCCGCTAGCCTGGCGTCAGTGTCAGGGTGGTGTTGCCGCTGTTGCGGTGGTTGGGATCCTGGCTGCTGGTGATCTGGCTCGTAGCCTCGCTGCCGCCTGATATGCGGGTTGGCGATCATGCGTTGTGCCGGTCGCCGGTGGTCGGGGCCGACCGGCGTGACTTGATAGGAGCGTGGCAGCGCCCCTCGCTGAGGTGTGTCCGCCGGCCGGCCCAGCCGTCCCTTCGAGCTGGAAGGAGACCATCCCCATGGTGGTGCTGGGTATCGATGTCCACAAGGGCACCCACACAGCGGTCGTGGTGGACCAGGTGGGCCGCAAGCTGGGCGAGAAGACCGTGCGAGCCACGGATGCCGGTCACCGGCAGCTGCTGCGCTGGGCGTTGCGGAACTGGCCGGATGCCGAATCGGTGTTCGCGGTGGAGGACTGCCGGCACGTGTCGAGCAGGCTGGAACGGGCGCTGCTCACCGCGGGGCAGACCGTGGTCCGGGTGCCGCCGAAGCTGATGGCTGGGGCTCGCTCGTCGGCGCGCACGCGAGGCAAGTCCGACCCGATCGACGCGCTGGCCATCGCCCGAGCCGCGCTGCGCGAACCGAACCTGCCGACCGCGACACACGACAGCGTCTCGCGGGAGATCAAGCTGCTGGTCGACCACCGCGAAGATCTGGTCAACACCCACACCCGGATGCAGAACCGGCTGCGCTGGCACCTGCACGAACTCGACCCCGAGCTCAACCCCACCGCACGGGGACTCGATCGGCTGTGCGAACTGGACCGGCTGGCCGCCTGGCTCCATCAACAGCCCACGTCCATGGTGGTGCGCATCGCCGCCGAGCTGGTCACCGACATCCGGGCCCTCACCGTCCGCGCCAACGCACTGGAGCGGGAACTCGCCCAGCGAATGACGCACGTCGCGCCCCGCCTGCTCGCCTTGCCCGGCTGTGGTGCGCTGACCGCGGCAAAAATCGCCGGCGAGACCGCCAACGTGACCCGGTTCCGCTCCGAAGCCTGCTTCGCCATGCACACAGGTGTCGCCCCCATCCCCGCCTCCTCGGGCAAGACCAACCGGCATCGGCTGGCCCGCGGCGGCAACCGGCAACTCAACGCCGCACTGCACCGCATCGCCGTCACCCAGATCCGCCTGGACGGTCCCGGCCGCAACTACACCCAGCGACGCCGAAGCACCGGAGACACCACCATGGAAGCACTCCGCGCCCTCAAACGACGCCTCGCACCCATCGTCTACAACACCCTCCAAGCCGACACGACCACCCGACCAACCCACCACCCAGCAGCGGCTTGA

Protein sequences of DBSCAN-SWA_1

>NC_017186|1538493:1582883|1546816_1547140_-|WP_013223344.1|transposase|DBSCAN-SWA
MPPRKRRSYPAEYKVEAAHRVIDSGRTIAEVARELGLDAGMLSVWVKDERRRVTAAEVHGENPLEAAERAELLRLRGQVAELEKDNAFLVKASAYFAAMQKNRPGSL
>NC_017186|1538493:1582883|1543225_1543651_+|WP_013223350.1|DBSCAN-SWA
MQALESLISYTLAMFEYHGWITLRSTAEALDDEPPLRLGEIQDLVDELAGYALMDLQPMNGTYYIHLGGNPNRSGQRGPAVIDLFAKVGRLAPGSYGLLYVHDADHTLSFRVFRLVRGTVTEHPDHLLSPVIPTLEDAETS
>NC_017186|1538493:1582883|1578747_1579572_-|WP_013223378.1|DBSCAN-SWA
MSDGRWFDGWSPWPELAGLAAAGRSLLPNVPVTPAALVRTVTEQLVGRRLTAQVGGREVGLTLAELDYPADSLRLATGRLGDVRIVAEDVDWPEPEDDGEPGTIPLRRVTVFAEDVRLRSLPTPAAKPARVQLAIAVSAEVLQDRVAKARPGIVATPADGGLLRIHWAKRPHWGHLTLRPQVAADGVVLVPQTLHIGQRQLRPPRRFRPIVLPLPELPPGLNLTKVEPRHDELVLHTVAEEWPDRLSRIPLPDLLSWLTTAAMTLTLPNLGTRS
>NC_017186|1538493:1582883|1540858_1541356_+|WP_013223347.1|DBSCAN-SWA
MSWLPDDFVHPVYTPVPGTALHLRPIRETDTAIDYPAVMGSRERLWSIFGPAWSWPKETMTYEEDRLDLLRHEKEIAAHQSFNYALLDEEETAILGCVYIDPPERTGSDGEVSWWVVDDLVGSEVERALDALVPQWIATDWPFRRPRFLGRDITWQDWLALPPIS
>NC_017186|1538493:1582883|1545899_1546730_-|WP_158314388.1|transposase|DBSCAN-SWA
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA
>NC_017186|1538493:1582883|1539791_1540184_+|WP_013223346.1|DBSCAN-SWA
MRAVARKKVPFEGTWTKAPYPERSHDGRTFAVLVDDPEIEALVVDRATGEVFVLDGSVGLVNRSLSRFAESAAAYAAARKRAKSIDEDDDEALEANGEQALKAIRAIDADAVADENQFWAVATEELGYGM
>NC_017186|1538493:1582883|1574304_1575381_+|WP_013223374.1|DBSCAN-SWA
MKRRVSIGLAVVLVLAVVGVIIWGRGDDSAAGSTTTVRGVIGSEKQAFFTDQRVVDAFARHGLKVEVDTAGSRQIATTVDLGKYAFAFPSSSPAAQKIQRDRKVTTVYTPFQSPMAVASFEPIVSLLRANGTVHKGAGDYDVLDIAKYLDLTKAGTRWDQLPGNTAYPARKNVLVTTTDPRESNSAAMYLSIVSFVANGNAVVSTPDQEAKVLPSVAKLFLDQGYTQNSTEGPFEDYLSAGMGKTPLALIYESQYVGRVLSGDGSIRPDMRMLYTAPTVYSKHTLVPLTGDGDKVGQLLATDPELGRLAATFGFRTTDPKLFAEVAASAHPPADLVDAVEPPSFETLERLLDAVGKQY
>NC_017186|1538493:1582883|1545419_1545557_+|WP_014466672.1|DBSCAN-SWA
MRIIVLPVLDQQIRSAGTSTYLVPELVHASGAYDDWLRELVRKLA
>NC_017186|1538493:1582883|1541423_1541933_-|WP_013223348.1|DBSCAN-SWA
MEAATRALTSGSGPVKIEAIAREAGVGVGTLYRNFPSRDALVEEVYRSELARLCAMAADLVTELPPTDAMREWMRRYQDFVATKRGMAEALRAVIASGALNSGHTRERLEVAIATILDAGRADGTLRADVRPADISASMAGIMLAAADTDQATRMLQLLVDGLLARDNS
>NC_017186|1538493:1582883|1571306_1572728_+|WP_013223372.1|DBSCAN-SWA
MSALPREELRGLFLFEHLSEAQLDWVAANGVIEEYEGDTFVIREGDEATCFYVILNGAVRMTRLVSGTEVETNRSDQRGAYFGATQFFVHQDAEHRYGASVQALSDLTLLALPSKEFSTEFRRWFPMATHLLEGMYLGWRNSDTVIGSRRRLLALGELSAGLTHELNNPAAAAVRATSALRERVAGMRHKLAFLAKKDIDPELLYQLIDVQERLVKQVVQAEKLTAMQQSDREDEIGDWFDDRGIDGGWDLADIYVRAGLTTADLDNVLEQVGDTFIDGAVRWLAYALETEMLMGEIEDSTTRISALVGKAKQYSQMDRAPHQWVDVHDGLDSTLVMLSGKIGGGIRVVKEYDRSLPKIPAYPAELNQVWTNIIDNALGAMKGEGTLRLRTWRVDDQIRVEIGDTGPGIPADIKPRIFEPFFTTKPVGEGTGLGLDISWKIVVERHQGDLRVESEPGNTRFEVCLPTVEQASL
>NC_017186|1538493:1582883|1579648_1579903_-|WP_013223379.1|DBSCAN-SWA
MRVITAIGAIFAGIEVLYMIMVLAGANAGNSFFQFIKSLAVPLALFWPGLFPVGDGNLQVILDFGLAAVFWLVVTGIIARFAGR
>NC_017186|1538493:1582883|1581830_1582883_+|WP_013223381.1|transposase|DBSCAN-SWA
MVVLGIDVHKGTHTAVVVDQVGRKLGEKTVRATDAGHRQLLRWALRNWPDAESVFAVEDCRHVSSRLERALLTAGQTVVRVPPKLMAGARSSARTRGKSDPIDALAIARAALREPNLPTATHDSVSREIKLLVDHREDLVNTHTRMQNRLRWHLHELDPELNPTARGLDRLCELDRLAAWLHQQPTSMVVRIAAELVTDIRALTVRANALERELAQRMTHVAPRLLALPGCGALTAAKIAGETANVTRFRSEACFAMHTGVAPIPASSGKTNRHRLARGGNRQLNAALHRIAVTQIRLDGPGRNYTQRRRSTGDTTMEALRALKRRLAPIVYNTLQADTTTRPTHHPAAA
>NC_017186|1538493:1582883|1548066_1550757_+|WP_013223353.1|DBSCAN-SWA
MMTKSTAAVHRTIVVVDVEGFGAWQRTNHHQLAVRRGLYSCLRTSFDRAGIPWESCETEDRGDGVFVLAPPEVPKSLFVESLPARVVDALAEHNHLHGPEARIRLRLAVHAGEINYDDHGVTAASVNLTFRLANSSELKAALAGSRGILALITSNWFFDEVVRHSIAARPGTYRNVTVSAKETVTSAWIALPDNPYSDIVDPARQPSPAAGAERPVLPIPRHLPASTAHYTGRLPDIAKLDSLLVEPGASGPGETTIFLIVGAAGMGKTALAVHWAHAVRSQFTDGDIYIDLHGYDPVAPTPLEQILERVLRALGVTTRNMPADLEGQTALYRSLLADRRVLIVLDNAATPEQVRPLLPGSATCRVLITSRHRMSGLVAREGAARLTLDPLHPTEAYSLLGQIVGEDRVAVEGAAAAEITRACAYLPLALRIAAERVAAHPRLTLAELARQLSGERDRLDLLAADDDESTAVRVVFSWSYRALPPAVSHVFRLLGLHSGPDISLPAAAALTNLTIEQTQRNLDALASVHLVEEVDHNRYRLHDLLRLYAAERAGEDETEADRSDAKLRLLTWYLHSADAADRQLAPRRRHAPLGEPPVGCRPLTFETQGRAWQWCEAERLNLVAATRQASAEAHLDIAWQLPTALWGYFTLRTPWVDWISAYRIGLAAAEQQADRSGYAWLLAGLGIAYRNLRRYDDAIDSFERALDVWRELGDRYAEAWTLGSLSIALWELERFADALARSQEALTLFRTVDSPYGESQALHCFGDACRGLGRYVEAIDYLQQALHLRRGSGDPGGESQILKSLGDTYRDLDELDKAEEHYRQALGMWREVGDRWSEARSLTAIGDIAKILGNLDTAVECWRQALEICEELGAPQTAEIDARLKHAANASSDKRQ
>NC_017186|1538493:1582883|1555827_1556256_+|WP_013223359.1|DBSCAN-SWA
MTTSAPATKAAWSSTLAAAGIGAVGGLLVNAAIAWAGQALLGAPDEFRQLTLPVYGPLTIIGALAGAIGWRLIVNRSRNAARLLTWLVPAVVALSLIPDLMLLSSKSQPGTTVGGVVALMLMHLGVAAVAVPAYRRFMPPRS
>NC_017186|1538493:1582883|1576506_1578114_+|WP_013223376.1|DBSCAN-SWA
MRKLWGLALAALLLAGCSDPAAAPQSESAPEPGTLRILAGSELADMQPVLDEAAQATGVKVKFTFTGTLEGAEALANGSADGKYDAVWFSSNRYPAGLPEAAKRLGNQVKIMSSPVVLGLATPVVQRLGWAGKPVSWGEIAAQAGKKAFSYGMTDPSASNSGFSALVGVASALAGAGNAIDARQIASVTPQLTQFFSAQTLSAGSSGWLSDAYVRRATGPDAVDGLINYESVLLSANASGKLPQPLTLVYPSDGVVTADYPLTLLADAGSDARSAHQRLADHLRTPAVQKRIMETTQRRPVVPGVALGPQFAQRDLVELPFPATQQAVDALLSAYFDKLRRPSRTLYVLDTSGSMAGARIDSLRSALVGLTGADTSLTGRFRRFRSREEVTMLPFNTGPGAPRTFTVPEENPAAELAQIKTFAEGLVARGGTAIYDSLSRAYQVLEPLMAADPDRFTSIVLMTDGENANGSSLPDFLTSLASLPPAMKQVPVFTVLFGEGSSDELTQVATRTGGKVFDARNVQLSRVFQEIRGYQ
>NC_017186|1538493:1582883|1551746_1553309_+|WP_013223355.1|DBSCAN-SWA
MPQPDLRRALIEEEQRIDAEMDLEAHNAKSPYNVAGYRPVRRELSHSPVRISGTLPADLDGAYLRNGTNTQFDDSKVRLHAFSGAGMIHEIQIRDGAATYSNFYVRTPRFEADRAAGREVYAEFSDLVAGRPGAQRLELVEKKIEAGMVPPLDPFERTPGSTSIRYHHGRLYCLQETGYAFVLNTQVDADGRLVLDGTGTLETWDGEWEGPFSAHPRIDPDSHDVYNISVERSGRIIAGQIHEGELVAQAEVHHQTSETGSMGWLHDFFLTAGHLVFPDISVRVAPTGLTGPDGSLFHHDGEYRMRWGVVPRVIDENVGVQWFETDHVGTIWHVINGWEQTGEDGHAQIVLHSPVFAGYPAGIPIHTPEEPPAQVKTWVLDLDTGKVVDDRLLLDHGYERPSLNLDYVGRPSRYCYLLDEHGDGYMGKGVLKYDLIDEKEVAYLDYGDMYGGEALFVPRSGSTEEDDGYLLDLLMAAERAELIIIDARTMIELARLHLPQRVPFGVHATWLTTEEIARLA
>NC_017186|1538493:1582883|1551284_1551707_+|WP_013223354.1|DBSCAN-SWA
MAARNQLVDALHEAIILFSRNTRVRANQMYDGMSFVAYSVLSYVGGRRDATASGLADSYHLEKSTVSRQLSELEAAGLLRRSANTDQPRTKRLELTAEGRRRLLDIRAHQRNGLQERLSSWSDEDVTRFAELFGRFVHDL
>NC_017186|1538493:1582883|1538493_1538817_+|WP_013223344.1|transposase|DBSCAN-SWA
MPPRKRRSYPAEYKVEAAHRVIDSGRTIAEVARELGLDAGMLSVWVKDERRRVTAAEVHGENPLEAAERAELLRLRGQVAELEKDNAFLVKASAYFAAMQKNRPGSL
>NC_017186|1538493:1582883|1568137_1568707_+|WP_013223369.1|DBSCAN-SWA
MTSFAAFTVVEPRKAWPLVAVRGVFAVLFGLFALIWPGATVLVLAILYGVYAIVDGIGGLMQAFRPGDTGHRVAYGVLGALGIVAGILVLVWPGITVLLLALLVGFWAIITGIAEVAAAIRLRKQIQGEAFLILAGAISLIAGILIVINPIAGAFGIALLVGIYALIYGIVLLVLAFRLRKLGTADAQN
>NC_017186|1538493:1582883|1572727_1574221_+|WP_013223373.1|DBSCAN-SWA
MASVPTVTTELGALVGQAGDGVRVWRGIPYARPPVGELRWKAPQPPSLSGGVHVATEYGPHAMQSPDPMNPAAVCDEDCLYLNVCTPEGPAPEGGWPVLFWLHGGGYRVGHGEQLGDGEEFARAGIVVVTINYRLGSLGFLHLAGIFGESEVDAGVCGFLDQVEALKWVRRNVSAFGGDPERITVYGVSAGAKSVGNLLGSPLGAGLFDQAISSSGGADHVATPEAGTALARRLLDEVGCQDLAALRSLPAKEFVEAQERILSGFQALWLWRPTLHPRVLPEVPIGPIRRGSAAGIPLLVGCNSNEGSTYAMMLGDDVATAPASGVLTNILGDAGASQLLETYLRRVPDLKAARIAALGDERYGIPTQRLADAQSAHAPVYRYRIDIAAPGVPEQLDGGHGTETTMAWKVPLPLAAQGTAVNPARERAALLVHRAWVRFIRDGVADADGPEWPPYGPELRPVLVFREDTDLVLDPRADERKAWGDTEWASGTWFPVT
>NC_017186|1538493:1582883|1561720_1562830_+|WP_013223364.1|DBSCAN-SWA
MDMRVHSLLELEEQYANLLAALDRGEALRRALALLADGSEVAWTARPDADGVLTLDQVTGDRTGVLRALRVPPSTGLTGKVFRAGRAEWVDDYFGSQEITHDFDRHIATENVRRVLAVPLLRDGETLGVLAIGPREDGTFGDREIEHASAIAAQAALAISLAERARLSREIAVHEERRRMAADLHDSVGALLFAIGSGMADLAESTQADPELRARLEGLRRQAVDATTALRESLRTLRSSPAALALGVALRADCEAFADRTGLPAELVILDEDPPELAPSRSDTLLTAVREALLNVEKHAHASAVTVSVQHSNPWLTVAVHDDGVGLGPDYTPGLGLTSSAEALGRLGGSVRVVSDPDGGTIWRARLPC
>NC_017186|1538493:1582883|1543761_1544259_+|WP_013223351.1|DBSCAN-SWA
MFVEGSSTALLRTAYLLTGDRGHAEDLLQTALLRTARHWPRARDSPQAYARTVLLNLSRDRVRALFRRPREAPMPPDVDTLHAVDAGYEQVSERRVVLRALAELPIRQRQVIVLRFFEDMSVEQTAGLLGFSSGTVKSHTSRALARLRELLADHDSLQEVPRAHR
>NC_017186|1538493:1582883|1556289_1557168_+|WP_014466677.1|DBSCAN-SWA
MTNRSVHDLLNLANPAGAYDALLTRVLPQARVQRRWEPSDGPLPSLFVSHGAPPTLDDPQWLDDLFTWGQAMPKPRGIVIVSAHWENAPAALSGSAAGTPLFYDFGGFHPRYYTLQYATPDATDLARRIASTMSSTGPVHQFTDRGLDHGAFIPLMAMYPAADVPVVQLSMPSLDPQALLRLGQRLRRLREEGILVIGSGFMTHNFAVMRKPALVDYTIAFDTWAADAISRGDVDTLTDYRAKAPGADIAHPTADHYVPLLLTLGAATDLSTATSAIERIHYGNSIRSIQLD
>NC_017186|1538493:1582883|1538903_1539734_+|WP_158314388.1|transposase|DBSCAN-SWA
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA
>NC_017186|1538493:1582883|1557304_1558240_-|WP_013223361.1|DBSCAN-SWA
MDYGTTPLHGLPSRVTICEVGPRDGLQNEQAVLPVEVKAEFVARLVDAGHTLIETTSFVPAKWIPQLADAEELLDAITLAPGVRYPVLVPNERGLERALAAGVRDIAVFGSVTETFARRNLNRTVDESLAMFTPVVARAREAGLGVRGYLSMCFGDPWEGEVPVERVVEVATRMMALGCTQLSLGDTIGVATPGRVVAVLDALAAAGIPVDAIAVHFHDTYGQALANTFTALGHGVTTIDASAGGLGGCPYAGSATGNLATEDLLWHLHGLGIETGIDLQKMVDTSIWLAAKLGRPSPSRAVTALGDPLPR
>NC_017186|1538493:1582883|1565814_1567992_+|WP_176742222.1|DBSCAN-SWA
MTRRRVMALLAAASVLVGSMTTTRAEAAVAPDGWYTVAAGNSGKCVDARGAGTADGTVVQQYTCNQTASQQWQFQSTGDGYFRINARTNPAAAWDVTNVSTADGGLLQLWTYGGGANQQWQAVDEGGNRYHFVSRNSGKCLDVPGASTADVQLQQYTCNGTAAQSFMLTPVNTSQPGQPDFGPNVVIFDPSMPSSAIQSRLDSIFAQQERNQFGSQRYAVMFKPGTYANDVNVGFYTQVLGLGLSPDAVTINGAVHVEADWFPPQNATQNFWRGAENLSVNPNGGADRWAVSQAAPYRRMHVRGDLQLDDGGWASGGWISDTKIDGQVRSGSQQQWISRNSQFGSWNGSNWNMVFAGVQGAPANTFPAPPYTTVGQTPVVREKPFLYLDSAGNYQVFVPSVKTNAAGTTWANGTAPGTSIPIDRFYIAKPGATAADLNAALAAGKNLLVTPGVYHLNQTLRVTRPDTVVLGLGIATLTPDNGLTAMTVDDVDGVKVAGLLIDAGTTSSATLMQVGPAGSAANHAANPTSLHDVFFRIGGAAVGKAATSLVVNSSNVIGDHMWIWRADHAERNEYVGWSTNTADTGLVVNGNDVTMYGLFVEHYQKTQVVWNGNGGRTYFFQNEMPYDVPDQASWMNGSTPGFSAYKVGPNVTSHEAWGLGSYCYFSTNPSVASAHAYEAPNTPGVRFHDMVTVSLNYQGTITHVINNTGPVTPSGTKAVNLVSYP
>NC_017186|1538493:1582883|1558241_1559888_-|WP_013223362.1|DBSCAN-SWA
MNGSYASGPSEVPLLGDTIGDDFDRTVAADPDREALVEVPTDRRWTYAQLRDDVDALALGLLKTGVVKGDRVGIWAPNMAEWTLLQYATAKIGAILVNINPSYRTHELEYVLKQAGISVLVSARAFKTSDYAGMIEEVRGNCPELRSVVLIGSGAWDELLAAGRCGDAARLAAAQAALSPDDPINIQYTSGTTGFPKGATLSHHNILNNGYFVGALCGYTPADRVCIPVPFYHCFGMVMGNLACTSHGATMVIPAQGFDPEATLEAVQRERCTSLYGVPTMLFIAELNHPKFAAYDLSSLRTGIMAGSPCPVEVMKQVVSRMGMEQVTICYGMTETSPVSTQTRMDDSLDLRVSTVGRVHPHLEIKLVDPATGLTVPRGEAGELCTRGYSVMLGYWNDPGKTAEAIDAARWMHTGDLAVMDADGYVNITGRIKDMVIRGGENIYPREIEEFLYTHPDIVDAQVIGVPDVKYGEELCAWVKLRDHAAEVTAETLRAFATGKLAHYKIPRYVLVVDEFPMTVTGKVRKIEMREKSVRILDLGEAAAIRNA
>NC_017186|1538493:1582883|1547240_1547672_+|WP_141748528.1|DBSCAN-SWA
MSSVAFAVIAASVCFTPGAVLWWMRYESVRRTGWRAVTVQAVIVSEPAGCLAVALAAVPGPSVDPERKLDYVVRYRDGEGARLRGGASLWHRPPLLAFDRAQPGWVGGTGRSCVVLFAGGGWGPRRPRAVPATFLADLPARPQ
>NC_017186|1538493:1582883|1542099_1543017_+|WP_013223349.1|DBSCAN-SWA
MTASRASAYGKLGDHDVLRVGFGAMQLEHADPDAAVRVLRRAIELGVDHVDTAQFYGPVNDLIRTALHPYAAGLRIVTKVGAVAHETERLVAAQKPAELRASVEENLRALGTDHLAVVDLRRADVPPGIVATGDQVVDLDSQLAELIALRDEGKIGGIGLSHVDLAQLRQALPAGIVCVQNLYNVLTRGHEDVLTECAEQGIAWVPYCPLGSAFDRLPSVTDNPVVLAHARRLGITPAQAGLAWLLGHSPATLLIPGTRNLAHLADNVAVARIELDHEATTAFDALAQDVSAQADLDAHSEASRR
>NC_017186|1538493:1582883|1564805_1565114_-|WP_013223367.1|DBSCAN-SWA
MQTDDEALRRSAPVALELPPADSSTDEAGRLLHTPAAAAERLTVGESWLRRKAGQRLIPCTFVGKHLRFTEDDLRAIIAAGHRGPSNRDQTGRPGRRRRTSH
>NC_017186|1538493:1582883|1580649_1581558_-|WP_013223380.1|DBSCAN-SWA
MLDADDVRRAVPMPAAVEAVREAFLDLAAGRFVVPQRLSFAGATTLVMTACHTPTSTTVVKTLNLVPGRAPMILGTLVWNTADGQVVADAVEVTTLRTGAVSGVATDLLAPAEASSLALLGTGAQAADQVRAVAAVRPMRRVTVFGRDLSRAEALAGRLSAEFPSVAIRVASSAPDAVSDAEIVCCATSSSTPLFAVDDLPDRVHVNAIGSYLPSMRELPAELLATAGCVVVDQVDAALEEAGEVIHAVESGVLDRGDLIELGAALRTPPVVSGRTVFKSVGLAVQDWAVARLLGDAASRGR
>NC_017186|1538493:1582883|1559884_1561570_-|WP_013223363.1|DBSCAN-SWA
MLDVTIEHDVPATMRDGVVLRADVYRPTADGPWPVLLARLPYGKNQPMLAGLMDPVGRARRGFLVVVQDTRGRYASDGEWEPWTYEMDDGYDTVRWAAALPGSNGSVGMFGPSYLGNTQWMAALAKPPELKAISPMVTWSEPDDGLFARGGAQELGITVPWSLMQGVDTLLRRYAGDPMAQGQALMALVGDTDAVAHTTYWELPAGHHPVFERHGIPELGFERSRREPEWSDSCRVAGRQAEIDLPSLHTGGWYDIFSQGTLDNFTAMRAAGRPANLIMGPWSHTGTMGYLGDVNFGMAASTELLGFRGRFADLELGWLRRWLSPGDEPSQPELPPVLLFVMGTNQWREEQEWPLARAVDTDLFLRAGNRLAFDAPETEEETGAFTYDSADPVPTTGGALLMSNEFPPGPLDQAKIEARPDVLLYTTDPLADDLEVTGRVRAHLTAATDAPTTDWVVRLCDVDTRGVSRNVVDGIVRAVATPGEFTEQVVDLWSTSYVFRAGHRIRVHVTSSNFPRWDRNLNTGEPLGTQSRPARQVIAHDASRLSRVVLPVVPAPAEGRA
>NC_017186|1538493:1582883|1562823_1563429_+|WP_013223365.1|DBSCAN-SWA
MLTRERTRIVIVDDHPVVHDGVAAQLQRYPDMVVVGHAGTGAEAVTVCAAEHPDVVLLDLRLPDCLAADVVPALHRVSPDSRILLFTAFPEHVAVAPTLAAGACGILVKHAGAIAIRDAIRSVVRTGAFRTGTPASSTAPVTAREYDVLRLVAAGHTNPEIGTELNLSINTVKTYLWTVMQKLAARNRAQLIANARGQGLL
>NC_017186|1538493:1582883|1578110_1578677_+|WP_013223377.1|DBSCAN-SWA
MMLRYLGSTKNLAGCVGGLLGVGLYLIGVVGWFWPFVVVALYAAGALLAPGEKVRLVPDASAGLRESLDALEATVSAQASRMPPSSVDTVHRIAEVLRDLLSRPRRLSGDPELQHAVVRLAGTDLPLSLETYLNLPRWFAARRAGAGSELVTQLGLLEAEAHRVAERFYATEVDRQADHTRYLRDRET
>NC_017186|1538493:1582883|1569657_1571310_+|WP_013223371.1|DBSCAN-SWA
MSQPILMTVDDDPAVSRSVARDLRRRYGKDYRVIRADSGPDALDALREIKLRGDAVAAILADYRMPQMDGIAFLEKAMDLFPHARRALLTAYADTDAAIQAINVVDVDHYLLKPWDPPEEKLYPVIDALVETWKAVGDKPVEEVKLIGHRYNSPSFHLRDFLARNAVPYRWYSVDDDEGGRILQAAEATDKDIPVVVTPDGTVLKNPTGSEIADAVGLSTRPAQEFYDLVVIGGGPAGLGAAVYGASEGLRTVLVEKKATGGQAGTSSRIENYLGFPDGVSGAQLTDRARRQAQKFGAEVLTARDVVGLQARGSQRVITFGDGSEIAAHSVILASGVNYRALEADGIEELSGRGVYYGSAATEAPECKGEHVYIVGGANSAGQAAVFFSRHASDVTILVRGASLESSMSHYLIEQIAGIENIHVRTHTTVKEVHGDGHLERLTLCENGVTETVDTGHLFIFIGAAPRTDWLGDAIHRDEHGFVCTGPDLLSAGQRPAGWPLDRDPHYLESSIPGVFVAGDVRSQSVKRVASAVGEGAMAVTLVHRYLEEQ
>NC_017186|1538493:1582883|1554790_1555732_+|WP_013223358.1|DBSCAN-SWA
MRAIHVPAAGEQPQVGDLPVPAVADGSVLIRVKAAALNPVDNAIAAGYLAGMLPHEYPLVLGRDAAGVVEAVGAGVEHVKPGDEVFGHVLLAPPVQAGTLAEYAVLPAAAVAIKPAALSFVEAAALPLAAAAAVQAVDAIEAKPGQTVLVNGASGGVGSYAVQLLAAGGVTVIATGSDTGRLTGLGATTVVDRAAGPIAEQVLAAYPGGVDAVVNLFGHSADDIPLAAVRRGGKVSALTQVPEADAGTAAGVTVTPIMAAAVREVTGPLAEQAAAGTLKVDVGSVITLDQALDGLATIAAGHAKGKTVVTLDN
>NC_017186|1538493:1582883|1575382_1576510_+|WP_013223375.1|DBSCAN-SWA
MDFALTPPEPVTAIPSERAAGLITLSEDTRSAVSVRASEFASRLEALDVRSPEFTDLLDELLTVGEADMRAAAGVAGTMLDRSLRSAASPQDGVTTSLASLRRTVAELDPAKLPLTGRKLLGVFPVAAGAKRALDRYRAANEPVNALVVDLRGRQDVLRRDNASIKGERERLWKVMGKLAEAAALAEAVDGAIEAQAGVFDLTDPARANALRADVLYPIRQRHQDLLTQLAVSAQGYLALDLVRKNNDELIRGVERAVSTTVSALRVALLVSGALASQRDVLDEVAALQATTDGLIRANTELLDLQSAEIRRASSDPAVATETIRQSFDRIYASIDAIDGFRADAVRTMATTVESLSGEIRRAEDHLRRSHEGEA
>NC_017186|1538493:1582883|1568720_1569635_+|WP_013223370.1|DBSCAN-SWA
MSTRELVVLGTASQVPTRHRNQNGYLLRWDGEGILFDPGEGTQRQMLRAGVAATDITRICVTHFHGDHSLGLSGVIQRLSLDKVAHPVDAHFPASGAHYFERMRHATAFYEQADLREHPIAEDGPIATGKLTLEARRLSHPVEAFGYRLTEPDGRTMLPERLREHGIAGPDVGRLQREGRLGTTTIEDVSTPRHGQRFAFVMDTRLCDAVYALSENADMLVIESTFLAEDTSLAKDFGHLTAQQAARVAAESGVRQLVLTHFSQRYPDPARFLEEAKGEFDGEIVVAQDLERVQVPKRRSFPTA
>NC_017186|1538493:1582883|1540495_1540663_+|WP_155258922.1|DBSCAN-SWA
MLFGDGKVRADYTDFVERQIADVRRVHAGEEDLSASHAEPSASPNGERLVARHPV
>NC_017186|1538493:1582883|1554357_1554738_+|WP_013223357.1|DBSCAN-SWA
MNIVLWIIAGLLAAAFAAAGAMKLTQPKEKLAASGMAWTEDVSPGLVKLIGGLEVLAAIGLILPAVLDIAPVLVPFAALGLVLIMIGAIVTHARRKETQAIGINVVLLLLAAVVVWGRFGPYSFGS
>NC_017186|1538493:1582883|1553715_1554252_-|WP_013223356.1|DBSCAN-SWA
MSDVAEPRWLDEEQLQTWLTLTGMLARLPVAIDAQLQRDAQISHFEYQVLAGLSMTPEHTLRMSVLAAFAEGSLARLSQVVARLEKRGWVRRAPDPTDGRFTLAILTDTGWDKVVATAPGHVAEVRRLVFDTLTNTQQRQLRDISRRVVRAIDPNDPCLDGVPFDTVADHTRTSTTDK
>NC_017186|1538493:1582883|1563567_1564686_-|WP_013223366.1|integrase|DBSCAN-SWA
MPWTEPAGDDTWRVRYRRTDGTKGAISGFPTATAADDHISTMLHEQRTGTWIDPEDGRTTIAQFAPAWLDSLDIDQRTEENYRSFLKIHILPRWGTTTFSELTNLGIRTWEKKLRASGLAKTTVDSIIKCFSLLLSDAVPEKLIAANPLVARRRRAQRTPCKIWGEPAEVLHVADQVALKYGPCGAVLIVTGGWTGARWGELTGLDRDNVHLYDDDTGSIYLDPDIGALHEPCSGPLYLSHLKTDESERTISLPPFLVRLLRWHMTTHNHRQVFVTPNLEWHRRSNFSRRAFRPAADGNHHIPNPAIRLQPAKPGLTFHGLRHSHKTWMIDDGWSAAAVSTCRDKLLPAELPGLLQALFEDRFPLAPLALAA
>NC_017186|1538493:1582883|1544245_1545196_+|WP_013223352.1|DBSCAN-SWA
MLTDEQYGRRIGDRLRHELDDVHASPDLVRKLRHRRTRRTWAITGAIATPVAAAAVVAVVVSTQATPHRSTTAAPTSAASTSAQPRIVTVAYIQAETVKALGQGTQYVIYSKDTYESGYYETWTDKATQRYRNDIYTRLPAATQAGRAGDGKMTLPSGPPTAPSGPPHRQQSHAVKGPGESQEITTVDWENKWWSVDHLRDDKPQTPIPDPTDPDGMRKAVAEGKVELVGQEKIGTVDTHHLRVIGPRREYKIDLWVDSTTYLPVKETAVKAGNKQGGDEFPESKGEAITYTWLPRTEENLAKLTLTPPADFKQLK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013223344.1|1538493_1538817_+|transposase	IS3 family transposase	NA	NA	NA	NA
1538692:1538710	attL	NA	NA	NA	NA
WP_158314388.1|1538903_1539734_+|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-30	33.0
WP_013223346.1|1539791_1540184_+	SUKH-4 family immunity protein	NA	NA	NA	NA
WP_155258922.1|1540495_1540663_+	hypothetical protein	NA	NA	NA	NA
WP_013223347.1|1540858_1541356_+	hypothetical protein	NA	NA	NA	NA
WP_013223348.1|1541423_1541933_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013223349.1|1542099_1543017_+	aldo/keto reductase	NA	NA	NA	NA
WP_013223350.1|1543225_1543651_+	hypothetical protein	NA	NA	NA	NA
WP_013223351.1|1543761_1544259_+	SigE family RNA polymerase sigma factor	NA	NA	NA	NA
WP_013223352.1|1544245_1545196_+	hypothetical protein	NA	NA	NA	NA
WP_014466672.1|1545419_1545557_+	hypothetical protein	NA	NA	NA	NA
WP_158314388.1|1545899_1546730_-|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-30	33.0
WP_013223344.1|1546816_1547140_-|transposase	IS3 family transposase	NA	NA	NA	NA
WP_141748528.1|1547240_1547672_+	hypothetical protein	NA	NA	NA	NA
WP_013223353.1|1548066_1550757_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_013223354.1|1551284_1551707_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_013223355.1|1551746_1553309_+	carotenoid oxygenase family protein	NA	NA	NA	NA
WP_013223356.1|1553715_1554252_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013223357.1|1554357_1554738_+	DoxX family protein	NA	NA	NA	NA
WP_013223358.1|1554790_1555732_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_013223359.1|1555827_1556256_+	hypothetical protein	NA	NA	NA	NA
WP_014466677.1|1556289_1557168_+	dioxygenase	NA	NA	NA	NA
WP_013223361.1|1557304_1558240_-	hydroxymethylglutaryl-CoA lyase	A0A1V0SKU2	Klosneuvirus	1.7e-36	33.6
WP_013223362.1|1558241_1559888_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.7e-26	29.8
WP_013223363.1|1559884_1561570_-	CocE/NonD family hydrolase	NA	NA	NA	NA
WP_013223364.1|1561720_1562830_+	GAF domain-containing protein	NA	NA	NA	NA
WP_013223365.1|1562823_1563429_+	response regulator transcription factor	NA	NA	NA	NA
WP_013223366.1|1563567_1564686_-|integrase	tyrosine-type recombinase/integrase	B4XYR4	Lactobacillus_phage	4.2e-05	24.1
WP_013223367.1|1564805_1565114_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_176742222.1|1565814_1567992_+	RICIN domain-containing protein	NA	NA	NA	NA
WP_013223369.1|1568137_1568707_+	HdeD family acid-resistance protein	NA	NA	NA	NA
WP_013223370.1|1568720_1569635_+	ribonuclease Z	NA	NA	NA	NA
WP_013223371.1|1569657_1571310_+	response regulator	G3MA85	Bacillus_virus	2.7e-32	30.0
WP_013223372.1|1571306_1572728_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_013223373.1|1572727_1574221_+	carboxylesterase/lipase family protein	A0A1S5V000	Saudi_moumouvirus	1.7e-33	35.7
WP_013223374.1|1574304_1575381_+	hypothetical protein	NA	NA	NA	NA
WP_013223375.1|1575382_1576510_+	toxic anion resistance protein	NA	NA	NA	NA
WP_013223376.1|1576506_1578114_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_013223377.1|1578110_1578677_+	hypothetical protein	NA	NA	NA	NA
WP_013223378.1|1578747_1579572_-	hypothetical protein	NA	NA	NA	NA
WP_013223379.1|1579648_1579903_-	hypothetical protein	NA	NA	NA	NA
WP_013223380.1|1580649_1581558_-	ornithine cyclodeaminase family protein	NA	NA	NA	NA
WP_013223381.1|1581830_1582883_+|transposase	IS110 family transposase	NA	NA	NA	NA
1589764:1589782	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017186|4670147:4677779|DBSCAN-SWA
GTCATGACTGCCTCCTGGGATGGGTGCCGACGCCGACGTGGGCGAACCCGGCCTCGGCGAGGACGTCGGGATCGAGCAGGTTGCGGCTGTCGACGACGACCGCCCGGTCGGCCGCGACGGCCAGCCGGGCCCAGTCGAGGTCCCGGAACTCGGGCCACTCGGTGAGCACGACGAGCGCCGCGGCGTCCTTGGCCACCAGGTACGGGTCGTCGACGACCTGGACCGCCCCCGTGCCGGGCACGCACGCGACGGCCGGGTCGTGCGCGGTCAGCTCGGCACCCGCGCGGGCCAGGTCGTCGGCCACGGCCAGGGCGGGGGAGTCGCGCAGGTCGCCGGTGCCCGCCTTGAAGGCCAGGCCCAGCAGGCCGATGCGGGCTCCGGCGAGGGACCCGGCCGGAGAACCGGTCACGGCCTGCCGCACGGCCCGCACCACCCGGGCGCGCTGCCGGGCGTTGACGCGGACCGCGTCGCGCAGGATGCCGAAGTCGACGCCCGCCGCCTCGGCCGCGTGCAGCAGGGCGGAGGTGTCCTTCGGCAGGCACGAACCACCCCAGCCGGGGCCGGGGGCGAGGAACTCCGGGCCGATCCGCGCGTCGAGGCCCATGGTGCGCGAGACCTCGCGGACGTCCGCGCCGAACCGCTCGCACAGTTCGGCCAGGACGTTCACGTAGGACAGTTTCACGGCGAGGAACGCGTTGCTCGCGTACTTCGCGAGTTCGGCGCTGGCCGAATCGGTCGCCACCACCGGGGCGCCGGTCGGCTCGTACAGCCGGGCGACCCGCCGCGCCGCCGGCGAGTCCGCCGGGTCCGTGCCGACGACGACCCGGTCCGGGTGCAGGAAGTCTTCGACGGCGTGCCCTTCGCGGAGGAACTCCGGGTTGGCCACCACCGGCAGGTCGTCGCGGCCCAGCAGGCGGGGCAGCCGCGCCGCGGTGCCGACCGGCACCGTCGACTTGGTGACCAGCACGCAGCCGGGCCGCAGCAGCCGCCCGAGCTGCGGCACGACGTGTTCGAGCACGCCGAGGTCGGGGCGCCCGTCCTCGGCCGGCGGCGTCGGCAGGCACAGGAAGACGAGGTCCGCGCCGTAGAGCTCCGACTGGGCGGTGGTGAAGCTCAGCGTCCGGTCGGCGAGGCCCTGGCCGACGAGCTCGGCCAGACCGGGCTCCGCGATCGACACGACGCCACGGCCCAGTTCGTCCACTTTGGACGCGTCGGCGTCCACGCAGGTGACCCGGTGCCCGAGCCGCGCGAAGCAGCCGGCACTGGTCAGCCCGACGTAGCCCGCGCCGACGATCCCGATGTGCTCAGCCATGCGCCACCCGCACTTCCAGGGCCGAACGCGTCGCGGCCAGCACGCGCTCCTCGCCGAGCAGCAGCAAGCCGCCGTCGGGCTCCTCGCCGTGCGGGTCGCCGACATTGCCCGCCCACAGCACGACGTGCTGCCGCGCGGACGGCGGCGGGCCCCACAGCCGCGGCGGCGTCGGGCCGAACAGCAGCACCGACGGCGTGCCGAACGCCGTGGCGAGGTGTCCGACACCGGTGTCGCCGCAGACGACGAGTGCCGCCCCGGCCACCAGCGCGGCCAGTTCCGCCAAGCCGGTGCGCCCGGCCAGCACGGCGTCCTCGCCGAGCCCGGCCGCCTCGGCGATCGAAACCGCGAGGTCGCGTTCGGCGGCGCTGCCGGTGAGCACCACGCGGTGCCCGCGCGCGGCGAGGTCCCGCACGACGGTCGCGAACCGCCCGGGCGGCCACCGCCGGGCCGGGAACGCCGCGCCGGGGTGCACCACGACGGCGTCCGGGGCCGGGCTCGGGCCCGGCGGCACGGGCAGGGTCAGCGCCGACCGGTCCGCCGCCAGGTGGTGGTATTCGACGAGCCGGCACCAGCGGTCGACCTCGTGCAGGTCGTCGCGCCACTCGAGGCCCGCGACGTCGGGGAAGTCGGGGTGGCGGTGGGTCAGCAGCTCGGCGGGATCGGCGACGAGCAGGTCGTGGATGCTCTCCGGGCCGCTGCCGTGCAGGTTCACCGCGAGCCGCGGCGGCGGGCCGGGCCAGGCGAGCTCGCCGAGCTTCGGGGTCGGCAGCAGCTCGTCGACCGCGTCGATCAGCTCGACGAGGTCCCGCAGGCTTTCCGGCGCGGCCAGCACCAGCCGGTCGCCGGGGTACCCTGCGCGCAAGGCGCGCAGCGCGGGTACCGCCGTCAGCAGGTCCCCGACGCCGAGCGCGCGCAGGACGAGGACCGCGGCACTCACGGCCACGACCCCTCCTCCGAAGCGCACACGACCAGCTCGCGGACCTCGGCGCCCGGCGGCTGCTGCAGCGCGAACACGACGGTGTTCGCGACGTGCTCGGGCTGGTTGAGCTTCGCGTCCGGCGGCGGCTTGTACTGGTCGGTGCGGTCGTCGAAGAAGTGCGTCCACATCCCGCCCGGGATGAGCAGCGTGACGCCGACGCGCCCGGCCAGCTCGGCGGCGAGCGCGCGGGTGAACCCGACGACACCGAACTTCGAGGCGCAGTAGGCGGTCGCGTCGCTCACCGCCTTGATGCCCAGGGTGGACGCGACCGTGACGACTGTGCCGTGGGAGCGTTCCAGGTAGGGGAGCGCGGCGCGGATCACCGCGGCCGTGCCGAGCAGGTTCACCTTGACGACCCGCTCCCAGTCCTCTGTGGACACTTCGCCGAGCGGGCCGCAGGCGTCGGTGCCGGCGGCGGTGAAGACGCCGTCCAGGCCGCCCGCTCGCTCGGCGAGCTCACGCACCGCCGCCTCGGTCGCGGCGGTGTCGGTCAGGTCGGCTTCGACGTATTCGGCCGGATCTTGCGGGCGGACGCGGTCGAGGACGTACGGGGTGCCACCGGCCTTGCGGACGGCGTCGACGGTGGCGGCGCCGAGTCCGGACGCACCGCCGGTGATCAGGACGTTGCCGAGGGGTCGCATCGCTCTCCTTCGCGGGCGAGGGGGTTCAGGCACTGGCCGCCGCGGCGACCAGCCGGGACGTCGAGTAACCGGGCACGGTCGGGACGAGCACGACTTCGCCGCCGTGCCGTTCGACCACTTCGCGTTCGGGCAGGACCGCTTCCGCGTAGTCGCCGCCCTTCACCCACACGTCCGGGCGCAGCTTCTCCAGGACGGCGGTGGGCGAAGGCTCGTCGAAGACGGCGACGGCGTCCACAAAGGACAGAGCGCAGAGGAGTCGGGCGCGGTCGCGGTCGCGGACCAGCGGGCGGCCGGGGCCCTTCAGACCCCGCACCGACGCGTCGGAATTGAGGCAGACGACGAGCGCGTCGCCGAGGGCGCGGGCCTGCCGCAGCAGGCTCACGTGCCCGGGGTGCAGCAGGTCGAAGCAGCCGCCGGTGGCGATCAGTCGGCCGCCGGTTGCGCGGATCCGCTCGGCGAGGCCGAAGGCGTCGGTCGCCGGCTGCGGGTCGGGCACCGGGCCGTCGTTCGTGGACAGCGCGGTCGCGCCGCCGGCGGCGACGAACCGGGCGGCCGCCTCGACCGCGGTCACCACGGCTTCGGTCGTGTCCGCGCCGCCGAGCAGGGCCGCGGCGGCCGCGGCGGCGAACCGGTCGCCCGCGCCGCACGTGTCGGGCGCGGCGTGGCCCGGCATCCGTGCCGCGGCGGGGATCGGGACGGTCGTTTCGCCGAGGCCGTCGGCCAGCACCGCGCCGCGGGCCCCGGTGGTCACCGCGACCGCGTCGGCGTGCCAATGGCCGCGCAGCAGCTTGGCGAGCTCGGCCGGTTCCTCGTGCCCGGCGAGCACCGCGCGCGCCTCGGCGAGGTTCGGGGTGACCAGCCGCGTGCCGGGCACCGGCTGGGCGCCGCGGGGGTGCGGGTCCCAGACCACCGGGATCCGCTCGGCCAGCTCCCGCAGGACCCGCCGGACGTCCGGGTTGCGCGTCAGGCCGCGGCCGTAGTCGGCCACGAGGATCGCGCCGGCCTCCGCCAGGACGTCGTGCACCCGGGTGGGCAGCGGGTCGGCGGTCGCCGTGCCGTCGCCGGAATCCAGGCGCAGCAACGACTGCCCGCCCGCGCGGATCCGGGTCTTGCACACCGTCGTGCCGCGCAGCGGCAGCGGCAGCACGGTGACGTCCGGTTCCAGCAGCCCGGTGAGGGCGTGGCCGCCTTCGTCGTCACCCAGCGGCGTGACCAGGACGACCTCGGCCGCCGACCGCGCGGCCAGCAGCGCGGCCAAGCCGGCCCCGCCCGGGCGGCGGCGCCGGTCCGTCAGGTCGACCACCGGCACCGGCGCCTCCGGGCACAGCCGCTCGGCGGTGCCTTCGGCGTCGACGTCCAGCAGCGTGTCGCCGAGGACGACCAGTGGCCTCACGCGGTCACCCCGAGCGCGGTGTCGAGGGCCGCGCACAGGCCGTGCACCAGCACCAGGTGCATTTCCTGCACGGTCGCGACGGTCGGCGCTTCGACCGTCACGGCGTCGTCGCACAGGGCGGCGAGGGGGTTCGGGGCGGGCCCGGTCAGCGCCCAGGTCGTCACGCCCAGCTCGTGCGCGGCCTTCGCGGCGGCGACGACGTTCTGGCTGCCACCGCTGGTGGACAGGCACACCAGCACGTCGCCCGGCCGCCCGTGCGCGTGCACCTGGCGAGCGAAGACCTCGTGGTCGCCGTAGTCGTTGACGATCGCCGTGGTCGCGGACGTGTCCGCGTGCAGCGCGATGGCCGAGAGGGGACGGCGTTCGTGGCGGAACCGGCCGACGAGCTCGCCGGTCAGGTGCTGGGCTTCGGCCGCGCTGCCGCCGTTGCCGCAGGCGAGCAGCCGGCCGCCGGCTTCGAACACGCCGACCAGGTGCCGTCCCCACGCGGTTATCTTGGGGGCGGATTCGCGGGTCCGCTCGGCGGCTTCGGCCAACGCGGCGAGATGGTCTTCCATCACGGCACCTCCTTCTCCTCCGGCGACGCCGCGCCGGTTCGAGTGGATCGGGGACGCCGGAGCACGAACGGCCCCAGCGCGAGCAGGTCGATCGGGGCCGAGCCGAAGCACTCCAGCGCGTCCCGCGGCGAGTCGACCATCGGGCGGCCCGCGGTGTTGAGGCTGGTGTTGATCACGACCGGCAGGCCGGTCCGGCGCTCGAAGCCGGCCAGCATCCGGGCCAGCACCGGGTTTTCGCGTTCTTCGACGGTCTGCACGCGGGCGGTGCCGTCCACGTGCGTGATGGCCGGGATGCGGTCGCGCCATTCTTCGGCGACGTCGTGCACGAACAGCATGTACGGGCTGGGCAGCGGGCCGCGGGCGAAGATCTCGGCCGCCCGCTCGGCCCGCACCATCGGCGCCACCGGGCGGAACTGCTCGCGGCCCTTGACGTCGTTGAGCCGCTCGAGGTTGGCCTGGCGGCCCGGGTGGGCCAGCAGCGACCGGTGCCCGAGCGCCCGCGGGCCGAACTCGGCGCGGCCCTGGAACCAGGCGATCACCTCGTCGTTCGCCAGCGCTTCGGCGACGGTCTCGGCGAGGTCGTCCGGTCGCTCGTAGGGGAGTTTGGCCTTGATCAGGATTTCTTCGAGTTCGTCGTCGGTCCACCCGCGACCGAGCCCGGCGTCTCCCATGGACGTGCGGGGCTCCCCGGCTTCGGCCGCGAGCTGCAGGGCGGCGCCGAGCGCGGTGCCCGCGTCCCCGGCGGCGGGCTGCACCCAGATCCGGTCGAACGGGCCTTCGGCGTGCAGCCGGCTGTTGGCGACGCAGTTGAGCGCGATCCCGCCCGCCATCGCCAGGTCGCGTTGGCCGGTGGCGTCGTGCAGCCAGTCCGCCAGCTCCAGCAGGATGTCTTCGAGGACTTTCTGGACACTCGCGGCGAGATCGGCGTGCTGCCGGCTGAGCTGCTCGCCGGCTTTGCGGCGTGGGGCCAGCGAGGCCAGGTCGACGCCGGAGGCGTGGAACCCGCCGTCGCCGGTGACGTGGACGTGCTCGCAGAGTTCGTCGAGGAATTCGGGCTTGCCGTAGGAGGCGAGCGCCATGACCTTGTACTCGTCGCTGGACCGCGCGAAGCCGAGGTGCTCGGTCAGGTCCTCGTAGAGCAGGCCGAGGGAGTCCGGCAGCTTCTGCGCCGCCAGTTCCTTGAACCGGCCGTCGCGGTACTCACCGGCCAGGTAGGACGTGCTCTCGCCGCGGCCGTCGGCGACGAGCACGGCGCAGTCGCCGAACGGTGCGGCGAGCGCGGCCGACGCCGCGTGCGCGACGTGGTGCCGGACGAACTTGACGATGCCCGGGTCGAGTCCGGGCAAAGCGGACTTCAGGAACAGGGGCGCCCGCTTCGCGAATTCCGTCCGCAGCTCCTCGCCGCTCGGGTCGTGCCCGGGCAGGCCCGGCTCGACCAGGGCGGGGTCGTAGGAGTATCCGACGGCGTCGAGGTCCTTCGCGGACAGCCCCGCCTGGGCCAGGCACCAGGCGGCGGCCTGGGCGGGCTGTTCCCACGTGGAGAACGGCACCGCCTGCTTGCCGTGCTTGCGGCGGCTGAATCGTTCCTCTTCCGCCGCGGCGACGATCTCCCCGTCCACCACCAGTGCGGCGGCCGGGTCGTGGAAGACGGCATTGATCCCGAGTATGCGCATCGACCTGCCTCTGGCGTTCCGGTGCGGACTCGTGAGGCCCGCTCTCGCCTATAGCGCTACCCGGCGAAGTCGTTGATAAACGGTCGCGCGCAAAAGCCCTGGGCGTCGCTACTCAGTGTGACGGAGCCCGGCGGAACCACGCCGCAGTGCGACGGAGACCGTCTTCGGAGTCGACCTTCGGTTCCCAGCCGAGGACGTCACGCGCGAGGGAGATGTCGGGACACCGCCGCTGCGGGTCGTCGACGACGGCGTCGATGTACTCGATCGGCGAGCGGGACCCGGTGAGGTGCTTGATGCGCTCGGCCACTTGGCGAACGGTCAGTTCCTCCGGGTTGCCGATGTTGACCGGCCCCGGGTGGTCCGCCCGGGCGAGGGCCAGCAGGCCGCGGGCGGTGTCCTCGACGTAGCAGATCGAGCGGGTCTGCTCGCCGGTGCCGGTGACCGTGATGGGCTCGTTCTTGAGCGCCTGGTCGAGGAAGGCCGGGATCATCCGGCCGTCGTGGGCGCGCATGCCGGGGCCGTAGGTGTTGAAGATCCGCGCGATCGCCGTGTCGACGCCGAATTCGCGGCGGTAGGCCGACGTCAGCGCTTCGGCGTAGCGCTTGGCTTCGTCGTAGACGCTGCGCGGCCCGATCGGGTTGACGTTGCCCCAGTACCCCTCCTGCTGCGGGTGTTCCAGGGGATCGCCGTAGACCTCGCTGGTCGAGGCGAGCACGAACCGGGCACGAGCGCGGCGGGCCAGCTCGAGCGCGTTCTCGGTACCGTGCGAGCCCGCGCGCAGGGTTTCCAGGGGCAGGGCCAGGTAGTCGCGGGGCGACGCTGCCGAAGCGAGGTGGAAGACGACGTCGGCTTCGCAGCTCGGCGGCATCGGCTGCGTGACGTCGTGGCGCACGAACCGGAACCCCGCGTAGCGGCGCAGGTGGTCCAGGCTGTCCGCCGAGGACGTCGCGAGGTTGTCGACGGCGATGACTTCGATGTCCTCTTCGAGCAGCAGCTCGCACAGGTGCGCGCCGACGAAGCCGGCACCCCCGGTCACCACCGCACGCCCGAACCGCCTGGTCACTCCCGGATCCGTCAT

Protein sequences of DBSCAN-SWA_2

>NC_017186|4670147:4677779|4675027_4676701_-|WP_013226120.1|DBSCAN-SWA
MRILGINAVFHDPAAALVVDGEIVAAAEEERFSRRKHGKQAVPFSTWEQPAQAAAWCLAQAGLSAKDLDAVGYSYDPALVEPGLPGHDPSGEELRTEFAKRAPLFLKSALPGLDPGIVKFVRHHVAHAASAALAAPFGDCAVLVADGRGESTSYLAGEYRDGRFKELAAQKLPDSLGLLYEDLTEHLGFARSSDEYKVMALASYGKPEFLDELCEHVHVTGDGGFHASGVDLASLAPRRKAGEQLSRQHADLAASVQKVLEDILLELADWLHDATGQRDLAMAGGIALNCVANSRLHAEGPFDRIWVQPAAGDAGTALGAALQLAAEAGEPRTSMGDAGLGRGWTDDELEEILIKAKLPYERPDDLAETVAEALANDEVIAWFQGRAEFGPRALGHRSLLAHPGRQANLERLNDVKGREQFRPVAPMVRAERAAEIFARGPLPSPYMLFVHDVAEEWRDRIPAITHVDGTARVQTVEERENPVLARMLAGFERRTGLPVVINTSLNTAGRPMVDSPRDALECFGSAPIDLLALGPFVLRRPRSTRTGAASPEEKEVP
>NC_017186|4670147:4677779|4670147_4671458_-|WP_013226115.1|DBSCAN-SWA
MAEHIGIVGAGYVGLTSAGCFARLGHRVTCVDADASKVDELGRGVVSIAEPGLAELVGQGLADRTLSFTTAQSELYGADLVFLCLPTPPAEDGRPDLGVLEHVVPQLGRLLRPGCVLVTKSTVPVGTAARLPRLLGRDDLPVVANPEFLREGHAVEDFLHPDRVVVGTDPADSPAARRVARLYEPTGAPVVATDSASAELAKYASNAFLAVKLSYVNVLAELCERFGADVREVSRTMGLDARIGPEFLAPGPGWGGSCLPKDTSALLHAAEAAGVDFGILRDAVRVNARQRARVVRAVRQAVTGSPAGSLAGARIGLLGLAFKAGTGDLRDSPALAVADDLARAGAELTAHDPAVACVPGTGAVQVVDDPYLVAKDAAALVVLTEWPEFRDLDWARLAVAADRAVVVDSRNLLDPDVLAEAGFAHVGVGTHPRRQS
>NC_017186|4670147:4677779|4673103_4674471_-|WP_013226118.1|DBSCAN-SWA
MRPLVVLGDTLLDVDAEGTAERLCPEAPVPVVDLTDRRRRPGGAGLAALLAARSAAEVVLVTPLGDDEGGHALTGLLEPDVTVLPLPLRGTTVCKTRIRAGGQSLLRLDSGDGTATADPLPTRVHDVLAEAGAILVADYGRGLTRNPDVRRVLRELAERIPVVWDPHPRGAQPVPGTRLVTPNLAEARAVLAGHEEPAELAKLLRGHWHADAVAVTTGARGAVLADGLGETTVPIPAAARMPGHAAPDTCGAGDRFAAAAAAALLGGADTTEAVVTAVEAAARFVAAGGATALSTNDGPVPDPQPATDAFGLAERIRATGGRLIATGGCFDLLHPGHVSLLRQARALGDALVVCLNSDASVRGLKGPGRPLVRDRDRARLLCALSFVDAVAVFDEPSPTAVLEKLRPDVWVKGGDYAEAVLPEREVVERHGGEVVLVPTVPGYSTSRLVAAAASA
>NC_017186|4670147:4677779|4672391_4673078_-|WP_013226117.1|DBSCAN-SWA
MRPLGNVLITGGASGLGAATVDAVRKAGGTPYVLDRVRPQDPAEYVEADLTDTAATEAAVRELAERAGGLDGVFTAAGTDACGPLGEVSTEDWERVVKVNLLGTAAVIRAALPYLERSHGTVVTVASTLGIKAVSDATAYCASKFGVVGFTRALAAELAGRVGVTLLIPGGMWTHFFDDRTDQYKPPPDAKLNQPEHVANTVVFALQQPPGAEVRELVVCASEEGSWP
>NC_017186|4670147:4677779|4674467_4675028_-|WP_013226119.1|DBSCAN-SWA
MEDHLAALAEAAERTRESAPKITAWGRHLVGVFEAGGRLLACGNGGSAAEAQHLTGELVGRFRHERRPLSAIALHADTSATTAIVNDYGDHEVFARQVHAHGRPGDVLVCLSTSGGSQNVVAAAKAAHELGVTTWALTGPAPNPLAALCDDAVTVEAPTVATVQEMHLVLVHGLCAALDTALGVTA
>NC_017186|4670147:4677779|4671450_4672401_-|WP_013226116.1|DBSCAN-SWA
MAVSAAVLVLRALGVGDLLTAVPALRALRAGYPGDRLVLAAPESLRDLVELIDAVDELLPTPKLGELAWPGPPPRLAVNLHGSGPESIHDLLVADPAELLTHRHPDFPDVAGLEWRDDLHEVDRWCRLVEYHHLAADRSALTLPVPPGPSPAPDAVVVHPGAAFPARRWPPGRFATVVRDLAARGHRVVLTGSAAERDLAVSIAEAAGLGEDAVLAGRTGLAELAALVAGAALVVCGDTGVGHLATAFGTPSVLLFGPTPPRLWGPPPSARQHVVLWAGNVGDPHGEEPDGGLLLLGEERVLAATRSALEVRVAHG
>NC_017186|4670147:4677779|4676813_4677779_-|WP_176742236.1|DBSCAN-SWA
MTDPGVTRRFGRAVVTGGAGFVGAHLCELLLEEDIEVIAVDNLATSSADSLDHLRRYAGFRFVRHDVTQPMPPSCEADVVFHLASAASPRDYLALPLETLRAGSHGTENALELARRARARFVLASTSEVYGDPLEHPQQEGYWGNVNPIGPRSVYDEAKRYAEALTSAYRREFGVDTAIARIFNTYGPGMRAHDGRMIPAFLDQALKNEPITVTGTGEQTRSICYVEDTARGLLALARADHPGPVNIGNPEELTVRQVAERIKHLTGSRSPIEYIDAVVDDPQRRCPDISLARDVLGWEPKVDSEDGLRRTAAWFRRAPSH

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013226115.1|4670147_4671458_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	7.0e-60	34.9
WP_013226116.1|4671450_4672401_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_013226117.1|4672391_4673078_-	SDR family oxidoreductase	A0A0K0KVL6	Prochlorococcus_phage	9.7e-05	27.8
WP_013226118.1|4673103_4674471_-	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase	A0A0F7LBI5	uncultured_marine_virus	4.3e-12	37.0
WP_013226119.1|4674467_4675028_-	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	5.9e-08	31.8
WP_013226120.1|4675027_4676701_-	carbamoyltransferase	A0A1B1IVF2	uncultured_Mediterranean_phage	8.9e-52	32.4
WP_176742236.1|4676813_4677779_-	GDP-mannose 4,6-dehydratase	A0A2K9KZK0	Tupanvirus	2.1e-66	42.6

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_017186|6405357:6460869|DBSCAN-SWA
ATCACGCTTCCCCTAGCGACCCGCCGCCTGCAACGGGATGCGGTTCGCGGGTGAGCACCGCGAGGGCCGCAGCAACGTCGTGGATCGAGGCTTTAACGTAGGTTGCGGTTGTTCCGGCCTGATTCAACGTGGTCGAACTCTGATGACCGGCATAGGCTTGGGCGACCGCGTAGCCATGCGTACGTTCAACCCAGGTGAGAGTCGTGTGGCGCAGCCAGTGGGTAGAGATACCTTGATGCGCGACCCATGGCAGGTGTCGTCCTACGCGGTCCCACAGGTGGTCGTAGCGACGCCTGGTGATGGGGCGTTTCCGTCGATAGCGCAGGAGCGGTTCATCGGGATCAACGGCGCCTCGACCTTCGCCGTGTGAAATCAAGTGGGCCATCAAGCTGGGCGAGACGGGTTGCCACCGACTGGTGTTCGCCTTCTCGCGCAGGTAGATCAGGCACTGATGCCGGTCGAGATCTCGTGGCCTCAGTTGCAAGGCCCCGCCGCGGCGGCATGCGGTCTCGGTGTGGAGCCGGAGAAGGAGTGAGTCGAGCTCAGGATCGTCGCCAGTCGAGCCGGCCACGCCGTTGATCTCTGTGAGTTCTAAGGCAGTGAGTGCACGCCGGGGCGATGGTAAGCGACGTGGCTTGCTGACGCGGGCAGCGGGATTCGCTACCCGTGTGATCAGCCGGTCGTCTTCAGCATGGTGGTAGAGGCACCTTGCTGCAGCGATGAAGCTCTCGGCTGCGCCGGTTCCGCCGCGGAAGTTGTTACGGCTGACCGCGTTCGCCTTGACTTCTTCGGCGAGTTGCTTGACCTCAGACGGGGTGGGTTCGTCGATTCTCCGACTTCCCCAGCTGGTTTCCAGGTGCTTCCAGTAGGAAGCGTAGGTAGAACGTGTACCTAATGACACAGCCGCGGCCACCACCGGAATATACTCGCTGAAGGTCGGCACAGACGTCGGGCACTCAGACTGATCAGCTACCAGGTCGGCTGGGTCGACGCCCAGCCGCTCCAGCAGAAGACGTGCCGCGGCCAGATCGTCAGCCCGGTCAGCGCAGCGTGACTGCTGTGCTGCCATGGTCACTGCGCGGCTGTCGCGCGCGCCGGGTGATAGCGGGACATCATCTGATCCAGGACCGAGAATGAGTGCACCACCAGCGTGTCGTGTTCAACCGCAGCCGCTAGTAAGACACCGTCGCCGCCGTGGATTCCGGACCGAAACCGCGCCGCAGCCGGAAGCACCACACTGCACTGCTTCGTTACGCGGCTCACGCTGCGTGTTGCGGGACGAAGTACAATGATACCGTCAGACGTCTGCAGTGCGAGCTGATCTCCAACTTTCCAGTTCAACGCAAGAAGAAGCCTTCGCGCAGACAGTCTGCCCGAGGAGTCAACTCGGCTGATCTCGTACTGCATGGACCCGTCGCTCAGCAATGACTGCAGTTCAGCCATTGGCAATACCGGAGAACGCTGAGCATGCATAGGCCGTGAATAGCTCGGAATGAGCGCTGCGACCACCGCGTCGGCAACAGCAGGGGACACTGCAGCAAACGGAGGCGAGTCGTCTCGAGCAACTTGCCCGCCAACGGCATCAGTCTGATCAACCACGGCATCTCCCGCCAGCTTGGCCGACACAAAGATCAACAGCAACCGAGTCCGGCAGCACCGCCGCGGCTCGCCAGCTCAACGTGTCTCGATGGTCCCGTCAGTTGAGATACGCCGTTTGCTGGACGTGTTTGATGCGCCTGTATTTCCAAGGTCACGGAGAATTTTAGGTCTCGGCCGTCTCGATTGGGCAGTCTCGCGAGTCCGCGAACGTCTCGCAGGAGTGGCCTGAGCTCCCTCCAGGTATCCGGCCGCCTGTTCCACGCAGCCAAGTGGGCTAGGGAGGTTGTCGAGTCGATTGTCAGCCGGCGGCGATAGTGCCAGACCGGTGGCCCCGTGCAAGCCCCCGGTACAGAACGCCGTATCCCCGATGAGGTACGCACAGCTACCACGCGGCCTGGACGTCGCTCCGACCTGGAGATCTCCGCGACACTGACCCTCGTCGAGTTCGGCCGAGGCCACTGGGGACGGTCATGACGCGAACTCACCGGCATGACCTGTCACTGGGGATCCAGTGTTTCTTCACCGGCCTCATCGCGGTCGGCGCCGCGTTCGCCTCCTACCGGCACGGCCTCCACTTCGCTCTGCGCTTCGGCGCGGACGAGGCGACCGCCTGGATCTGGCCACTCATCATCGACGGCCTGCTCACCATCGCTACCGTCGAGCTCTGGAAAGCTGCCGGGAGCAAGTGGCAGGCCTAGCTCGCGTTCGTATTCGGCATCTCGCTCTCGCTCTGCGCCAACATCGCCTCGGCTCCCGAACTGAGCATCTTCGGCATCATGGTGGCCGCTTGCCCGCCCCTTGCCCTGTTGCTCGCTGTCGAATTACTGAACCGAGCTTTGAAGCGCCGACGCTCGCCGTCGGCACAGGCCTTCAAAATCCCACGGGAAGCAGAGGCGGCCGACTTGTCCACAGAGTCGGATGAGCCTGTGGACAAAACCGCGGAGCAACGGATGTGGGAGTTCTATGAAAAAGAGCGGCGGCAGGGGCGCACGCCGACCGGGGCCGACCTCGACCGGATCGCCGGCACCCACAACTACGGGCGCCGCATCCTGCGCAAGTGGCGCGCCGCCGACCTGACCACGTCGACGACGACTTGATCCTCACTCCTGGCGGCGTCGCGGGAGGGATAACGATTTCGGCCGCGGCAAGACCTGCAGCCGGGGAAGGGGCAGGCTGCCGTCCGGTCGGCGGTGCCCGCCAGCCCGCTCCTTCCCGAGCCGGAGGAGCCGCATTCGCCACGCTTTCACGCCTGCGGCTTCTCCTCGCTCTGGATGATGTCCTCCGCGACTTCCTTCGGCACGGAACCATTGGTCTTCGGTCCGATCACTGGCGCCAGGACGACGATCCCGTGCATCCGCCGCGCCTGTGACCGAAGCGCCCGGATCTCCTGGGCCTGAGATTCTCCAGGAGCAAGGCGTTCGAGCTGGGCCAGGTGCGGCTCGAGCGGCGACAGATCGACCGACACCTCGGCCAGGGCCTTGACCAGTTCGGCGGTGAGCGGCCTTCTGGGCTCACCGGTCCTGATGTCCGGCCAGGTGACCAGGGCCCGGACACCCAGGCTGATATTGGACGCCTGAGCGAGGTAGTAGTCGACTTCGGACAGGACGTCGTGGACCGTCCGGTACACCGCGTCCCATGCGGTGTCGCGCCGGGCCGCGGCCGCGATCGCCTCCTCCTTCGCGCGCTGACAGTTGTCGTGCGCGATCTCGGCGGCTTCTTCCGCGAGAACCAAGGCGGTGGGCGGCCGCGCTTCGTCTTCGGCCCGCAACGCTTCCAGCTGCTCGAGCTTCGGGTTCTCCGCGTAGAGGTGGGCCAAGAACACGACCCAGGGCAAGGTCACGAACAACAGCACCAGGACCGGGGCCATGGCGTTGCGAAGGGTCCCGTCGCTCACCTGGGAGGCCCCGAGCCGAGCCGACGCGGCGAGCCCGAAGGAGATTGAAGCCGCCGTCAAGATCAGGGTGGCTCCCAGGCCGGGCAGGTGGCGGGTGATCCAGCGCGCCGCGCGCACCAGGTGACGGCTGCGTCCGGACGCCGACGACATCACGTACGCGGGGGCCTTCAGCATCCCGTGGCGCAGACGGGCGACGTGCTCCGCGAGAACGTGCGATGCGACGATCACGACCACCGGGCTGAGCAGGCCGAGGAAGAACCCGCCGGTCATGCCGATGACCAGGTGTCCCCAGTCCGTCCGCCCGACCTGCAAACCGCTTATGGTCAAGTAGATCTGGAAGAAGAACAGCTCGTCGAAAGCGATGACGACGCCGTCAGCCGTGCGGGCGAGCAGGCGCCGGTATCGGCGTTTGCCGCCGGTCTCCAGCGAGGCCAGGTCGAGGTGCCGGTCGGGGTGCAGGTGCGGCGGCGTCGTCCGCTGTGGCGGGTCCTCGTAGGACGGCGGCGGGTCCCGCCCTGGTGCTCCGGCATGTCGTCGAGGTCGGCCGGAAGATCGGCCATCCTCCGTTGATAGCGGAGCTCCTCGAGGCGCCGCGCGAGCAGGACGGCCCCGGCCCCTTCCCGTTCCTGGGCGAGAACGAGCTGCTCGTGAGCTTGTTCGAGCCCGCCGCCAGTCGAAGTCAGCTCGCCCTTTCTGGCCTCGCAGGCGGTGTACACACCCGCCTTGGCGATGAGCTCGCCACGTACGTCGCCGAAGACCTTCTCGCGCTCCGAAAACCGGGATCTGCCGTTGACCAGTTCGTGGATGAGGTCCTCTCGCATCCGCCGCTCGTGTGGCGCGAAGGGCCGGTTGCTGCGCCACCTGCGCCAGAACGAGGGTTTCTTCGGACGATCTTCACGACCGCGGAGGTCCGGCGGGTCGTCGTCAGTGCTCATGGGTCAGCGTCCTTTCGTGGGAGTGACGATGTCGAGGACGATCCGGCGGTTGCGTTGAGCAGCCTGCTCGATCAGGTTGCCGGCCGGGTCGATGTCGTTTACGACCTGCTCGCTGCTGCCCACACCGCGGGCGGGAGCCAGCGCCTCGGCCGGGACGTGCTGCTCGATGAAGTAGTTCCGCACTGCTTCGGCGCGCTGGACCGACAGGAGGTCCCGGCCGGGGATCGGGCCCCAGGTGGCGGTGTGACCGGTGATGGTGGCATGGGCGCCGGGGCCCTGCAGGATCGTCACGTACGGGCGGAGCACAGCTTCGGCGGCCGGCGCCAGCACGGGCGAGTTTGGGTCGAAGAGCGCCTGCGCCGACAGCGACACGCTGCCGGTGCCGACCGGCGGCTTCGGCTGCGGAGGTGCCGCGGCGAATACGGCGTCGGCGGGCACGTTCGCCGGTGCTCCGTCGAGGATGTCCCCGGACTTGCGTTCGAGCCGCGGTTTGGCCACGCCGGCGGCCTTGAGGATTTCGCCCCAGACGGAGACGATCCAGCGCTGCTCGCCCTCGGTCATCTGCCGCCGCCCCTGCGATGTCTGCCCCAGCTCGAGGATCTGCACGTCCACGCCCTGCAGACCCGGGATTTCGGCGTCGCCGGCGAGCATCTTGGCGACCGATTCCGGAGTGGCGTCGCCGGCCAGCGGGACGCGCAGGTCCAGCGGCGCGGTGTTGTCCAGCCCGTTGGACACGGCCACCACGCTGACCGGCCCGTGCTCGGTACCGATCTGGCGGCTGACTTTCTGCAGCGCGTCGAGCAGGCTGCTGTCGGGCTGCTGGGGGACGAGGGAGGAGGTCCAGGCATCGAGGCATCCGAGAACCCGGCGCACGTAGCCGTCGCGGTCGGCGTCGACGTCCGTGCGGTACCGGGCGACGCGGTTGGTCTGCTTCCAGAACGCCGCCCCGTCGCTGCGTCCCTGGATCTGGCCGACGTCGATGAGCACCCGGCCGCCGCCGGTGTGCGCGTCGAGCATGTCGTGCAGCTTCTCGCCCAGCTCGGCGGGCATCTTGATGCGCGGGGCGTCGGCGGTGTGGTCGACCAGCACCTCCAGGCGGGAGTCGGGGTCGCCCGGGTCCGGCGCCGCGGCCTGGTAGGCCGGCAAGGTCTCGTCGCACGTCGGCTCGTCGACCCCGCATGCCGCCGAGATCGCCATCGGGCAGCCGACGAAGACGCCGGCAATGAGGACACGCACTCGGGGTGGTCGCCTCCGGCGAGGTGAAGACATCGGTTCTCCAGTTCATCCGTTCGGTGTTCCTGTCCGTAGCCGGCGAGCGTAGGAAGGCCGATCACGACGGCGAGTCCACAAAAGAGGGGAAGAAATTGGACTTAAGGCCATGAGCGGCAGAGCACAGGACCTGACGCCGGAGGCGGCCGCCGAGCTCCTTCTCGAGAGCTTCCGCGGCGAGGGCTACCGCAAGCTCGACGTCAAGGCCTGCGCGCACGTGCTCGGCATCGGCAAGAGCAGCTTCACCAGCCGCTTCGGCCGCAAGCGCGCGATGATGATCATCACGGCGTTGTGGTGCTGGCTGGAGAATCCCGTCTCGCCGTGCACCGAACGCCACACCGTCGGCGAGGCACGACGTCTTCTCCACGACGTGGCGGAGAACATCGCCGGGTTCCTGCACCGCGAACGCACACTGATGGTTCAGCTGGTGTACGGGCTCAGCGACATCTCCAACTACGAAAAGAACGATGACGAGAAGGCCTGGCGGAGCGAGTCGTTCGGCGAGCCCTGGGCCACGGTGCTGCGCGCCGCGCGGACGCACAACCGCTGGGTCGGGTTCGCGCCGCGACTGCGAGAAGGTGTCGAGGTGGCCGCGCGAGCCGTCGGCCACCTCGACACCGCGGCGCACCAGTCGATGGCCGACGCTCTGTCGGACCTGCTGCTGCGCGTCTGGTGGCAGAACACCCACGCCCCGGCAACGGTGATCGCCGAGCAGGTGACGGGGCTGTGGTTCTCCGGGATGCTGCTGCCGGCGACCGGTCCGTGGGTCGGCCGGGCGTACGCGGCCGAACAACAGCTGCTCCGCGCGCTGCGGCCCGAGCATGCCCCGACCTGGGAGATCGCCAGCCGGACCGAACTGGGAACCGCACTGATCTCCGGCCAGACACTGTGGCGACGCGCGCTGCGGGAGTTCGGCCTGGCGTTGACGGAGTTCTCGCAGCTGGAAGATTCACTGCGCGCTCAGCCCAGCCCCCTGCTGATCGGAAGCCTGCGCAGCAGGCACGGACAGTGCGCGCTGCGCTACGGCGACTATCCCCAAGCGCAGACCAGTCTGACCGAGGCGCTTCGAGAGGCGCGCCGGCTCGGCAACGAACACGACATCGCCCGGGCGCGCACCAACCTCGCCGAGCTGTACATGCGGACCGGCCGAGTCACCGAAGCCCTGACCCTCGCCCGGCAGGCCGTCGCCGCCCGCCCGCTGCGTCCGGTCTGGTCCAGCCCCGTACCGCGATTGTGGGACGCGGCGGTGGTGAGCACGGTGGTGCTGACCCGGGCGCACCTGCACGCGGGCCAGGTCACGGATGCGGTCCGGCTGGCCGAGGACCTGCTTGAGGTGATCGACGGGGAGGGCGGGCGGGCGGTCGCGCCGGACGGCCCGACCGCCGCGCTGGCGCGCGCCACCCACGGCCGCGCACTGCTGGCGGCCGGTCACCCGGACCTCGCCCGCCGGTCTGTCACCGATGCCGTCACGGCCGCGGCGAACGCGACCGGCCGCCACTCACTGCTGACCAGGCAGGCACGGACGCTGGAAGCTCGCTGCTACCTGGCCCTCGGTGATCCGGAGTCCGCCTGCCGGATTCTCGATGAGCTCGTACAGGACGAGAACTGGGTAGCCGAGCACATGTCCTTCCGGCACGCCCTCTCCGTGCGCGTTTGGCTCGGCGCTGCCTGGCTTGCCGCGGGAGACGCCGCCCGCAGTGCGCAGGTGCTCGACGACGGCCTCGCGCTGCTGAGGCGTCACCTCACCGATCCTGATCCTCAAAGCATCGAGTACCGGCGCGTCGCCGCGGTGACGGCCTGGCAGCTCGATCAAGCCGCCGCGGTCGCCGACCTCGAACGGCTCGTCGACGCCTCGTCGTCCACGCCCGTCCTCCCGCGGCACGTCGACCTGCTGCACGATCTCGGCCAGGCTTACGCGGCACGAGGCGAGGGGCACCGTGCGCGCCAGACCTTTCGCCGCGCGCTGAGGGAAGGCGAAACCGGCATCGACCCCGCGCACCCCAGCGTGCTCGCGGTCCGCGTCGCGCTGGCCCGGCTGCAGCTCGACGACTCTCCGGAGCACGCCGCGAAGCTGCTGGAACCGGTCCTGTCCGACCGGCCGCTGGCCCACGGGCTGACGGCCCTGGCCAAGACGCACCCGCTGCTGTCCGCCGCCCGCTCACTGCGGGACCGGATCGCGAAGAGCTCCGGGACGCAGTGAGCGGGCGCGGACATCAGCCGTGAGCGAGACCGGCCCGCCGCCACCGCCGGTCCAGCGCGTCGGCGTACTCCTGCGGCACGCCTCGGCTGCGAAACCGCTTCTCCGCCAACACGAACGGACCCGCGACGTAGGCGCAAGCGAGCGTCGGCAGGGCGACGAACTCAGGACTGCTCATCGTCGCGGCCGATGCCATCGAAGGCGAGCTTGCCGCCGCGCGCGGTCCCCACTCGCCGATGCCGGGCAGTCGCGACAGGCGTTCGATCAACCCGGCGCGCAGCACGGCGATCTCGTCCGGCCGCTCGCTGATGAGGTAAGCGCTGATCTCGACCGCCGTGGCCAGGGCTTCGGCGGCAAGCAGGCGCCGGCCGAACTGCCAGCGGACCGGCGCGGCGCTCCGGGCGAGCAGGTCGAGGTGCGTGCCCACGTGCAGCCCGAGCCAGACCCGCAACTGTGCCTCGGTGATCAGGCGGGGCGTCGCGGCGAAGAGCGGTCCGCAGCCGGTCGCCAGCCAGCCGCGCCAGGTCAGCATCGCCGGAATCGCCAGGTCGGCGCACCGGTGGCCCCGGACCGCGGCCGGCCGGTCGACGGCCGTGCGCTCCAGGACCTCGGCGACTCGACGCGCGGTGGTAGCGACCCGGCGTTGGTAGCCCGGGCCGTCGGGCTCAGGCGCTTCCCGGCGGTCCAGGAGGCGCGCGAGACGACCGGCCGCTTCCTGTACAGCGTCCGGCAGACGGGTTGCGATCGGCCTGGTCGGGACGTAGCGCATCGACGGCATCGGCCGGATCCCGAACCGCGACACCGAGATGTCGCCGAGCGCGCTGACCCGCTCGGCGAACCGCCACCCGACCGGGCCGATCGACGGGACCACGCGCAAGACGGCATCCGCCAGGTCTCCGTCACCCGTGGCCAGCGCCTGCACCAGCAGCTCGGCCATGCCCCGCGCGCGCCAGTCCGCCCGCTCGCCGTCCCAGGCCGGCACGTCGAGGGCCGCCTCCACCAGCATCCCGGCCGACAGCGGCGTCGCGGTCATCGCTGCTCCCCGGCACGCGTTTCCGCACGGGTCCACAGCCGGACCCGCAGCAGGTGCCGCCGGGGATCGGTGAACGCCGTGCGGGAGTGCAGGACGCGGCGGTTGTCGAACACCAGCACGTCCCCGGCCTGCAACGGCAGGTCGAGCGCGCCGGAGGCAGCGGCCAGGTGCTCCCGGAAGCTCGCCGCAACGGCGTTGTGCGGACGCGCCACCTCGAGGTTGTCCCAGCGCCACCGGACGGTGTCCGAGGCCAGGACCGGGAACTGTCGGATGCTGCCGCCGCCGAACACCGCCGGCGGACGCCAGCTGAACGACGGCTGCCGCAGCGCGGTGACGACGTCGGCGTCCAGACCCGTGCGAGCGTGCCGCTGGTGCAGCAGCCGGCTGACGCCGCCGTCGGCCGCGGGACGGACGCACAGCAACGCCACCAAGTCCTCCGGGACGTCGCGGTAGGCGGCATCGGTGTGCCACTCGGCAGCGCCCGCACGCACACTGAACGTCGCGTGCACGTCCGTGGTGGCCGGCCGGACGGGCCAGATCGCGGTGCCACCGTCACGCGCGGAGATCTTCCCGAAGACGCTCATCAGGTCGCCGACCGCGCCACGGTCGACGGTCCGGCCGTCGGTGAACTCGCACCCGCGCAGCAGGACGAACCCGGTTGTGTGCAGGTGCCGACGGCTCTCGTCGATCGGCATGGAGAACGTCACGATCGTTCCTCGTTTCGCTTGCGTGGCCCCGCCGCGGGAGGCGGGTGACGACCACGCGCCGACGTTCTCGCCGTTTCCTGGGATTTCCGGTTTCCGGCTCCGTTCGGAACCAGCCCGGAAACTCCGTGCGGTGGCGCGGCCCGGGATTGGGCAAGATGGCGTCGTGACGGACGAGGTGGCGCTGGCGGCGCTGGGTGAGGTGCTGAGCCGTCGCTGCTGGAGCACCCAGCAGCGAGACGACGCCGAGTCCGCACAGCGCATCATCGACGAGATCGCCCGATCGGACATCGACAAAACCGTTCTCGTCGCTCTGCTCGGCGGCGTGCGCGCCGCCTTCCTGCCAGACGAGCTCACCGACGAACTCGCCGAAGCGGCAGCGACTTCCGCGCGTCAGCTGATGCCGACCCGGCTCGCCGATACCGAACGGCTGGCCGTCGCCGCCGCGCTCGGCGTCTTGGCGGACAGCGGGCGCCCGGCCCGCCGTACGGCCGACTTCGTGGCCGTGGCCCTTTCGGCGCACCACATCGAACAGGACCAGCTGGGGCGCTGGGCCGCCGAGCGGGCCCTTGCGGCCGCGGACGACCTCACGCCGAGCCAAGAAACGGCAGCGGCGTTCGTGCTCGCCCTGATCAGCCAGGACCGCGCGGATATCCTTCGAGCGTACGAACTGGCCGCGACTCTGCCGCCGGATGACCCGCGGGCCCGCCAGGCGGAAAGGCTGCGTGCGACCCTCCACCCGGATCTGCCTTCGCAGCTCGAGCCGGCCGGGGACGCGGTCCGCGCGGGCAACCGGGAGGCTGCCGCACGATCGCTGGCGGAGGACTTCGGCCGGCTTCACGACGAGACCGGGAATCCGGTCGTCGGTGGCCTGGCCGAGGCGATGGCCGCGCTGGGCGAACGGGAGGTGGACGTCGAAGCGGCCCGGCGCGGGCTCACCACGGTCGTGCGGGCCCTGCGGTCCCGGCAGCGCTACGGACAGGTGCCGGCAGTGGCCAGGACCGGCATCGACATGATCGCGAGCATGCTCACCATCGACGCCACCGCGGCCACGGCCGACCTGTTGGCCGAGTTCCTCGAGGCGCTGGCCGACGCCGGCCTGTCCGACATCGTCCTCGACGAGCACCTCGATGTCCTTCCGGCCCTGGTCCAGGCGCGGTTCGCCGATGTGGCCAGTGCCCTGCCCACCTGGCCCGACCTCGCCGGCTGCGTGCACGGCCTGCGGGGACGTCCGGCGTTGCTGCTGCGGCGGCAGCGCATGTTCGCCACGAAGAACGCGTCGGTGCTCAGCATGTACGTCGAGCCGCCGGACTCGGTCGCCATCAAGTCGACGTTGCTGACCGACGCCGACGCCGCGGTGCTGCGGAGGTTCGGGCGCGCCCGCCCGGCGGAGCTGCGCGCGACCGACCTGCGCGAGGTCAACCGCTTGATCAGCTCCTTGCTGCCGGCCGCGCTGCTGGAGCGCCTCGCCGATGCCGGTCGGCAGCCGATCGTGATCGTGCCGGACGGCGAACTGTGGTCGCTGCCGTGGCAGGCGGCGCCGGTGTTCGACGACGTCACCGTCGCCCTGACTCCTTCCCTGTCCGTGCACGCCCGGCTGGCTCCTACGTCAGGCGTCGTGCGCACCGTCGTCACCCTCATCGATCCCGGCGTCGAAGGTGCCGACGAGGTCAGCGCCGCGCTCGAAGCCGCCCAACGGTCGGGCACGCTGACCGTCGCCCACTACTCCCCCGGTGTTACGCAGACCTGCGATCTGCTTCTGGTCTTCGCCCACGGCGAGGGCACCGGCCTGAGCTTCCGCACCGGTACCGCGGCACAGCCGGTGCCGGCGCTGCAGGTCGCCACCGAGGTGAAAGCCGGCGCGGCCGTCGTGGCCGCCTGCCGGGCCTTGGCCGCGCCACCGGTCTCGTTTCCGATCACGCTGCCTTCGGCGATGCTGCTGTCCGGGTTCTCGACCGTGATCGGCGGCCTGTGGCTGCTCCCGGCCGAGCCGACCGCACGGATCGTGGCCGATCTGATCCACCGGCTCGCGTCCGGCACCGAACTGGTGACGGCCTTGACAGCGGCGCGTGCATCCGTGCCCGACTTGCTCGATCAGCGCTGGGGGCTGGCCGTGCATGGGCTCACATGACCGGCGAGCATTCCGAGGGTCGCCAGTCCCTCGAACACGACTTGGTCGTCGTGCTCACCTCCGTCCTCACCCGGGCCTGCACCGGCGCCTCCAACCCCGAGGACGCCGCCTTGGCCCGGAAGCTGGTCCACGACCTGCACCAGCCCAAAGTGGACAAGTTCGTCCGCGCCTCCGCCGTGGCCGCGGTCATGGCGGCTTTCCCGCCGCAAGAAGCGCCCGATCGCAAGCTCGTGCTCGCCGCCCGCACCAGCGCCCGGGTCCTGTGCGAGCCCGATCAGCCGGAACCGTGGATCCTGCTCGGCGGGCAGGCACTGGCGTTGCTGTCCGCGGGCGGGCACTCGGACCAGCCGGCCGTCGACTTCCTTCTCGCCGCCGAAGCCATGCGCAAGGTCGAGCAGTACAACCTGGCCACCTGGGCCATCCGGCGGGCACTGGCCGAGGGCGGGCTCGACCAGCAGCGGCTCGTACACGCACACCTGATGCTGTGGCTGGTCACCCATGATCCGGAAACCGGCGCACAAGCGCGGGCGGGCGCGGCGCTGCTGCCCGAGGACAACGTCGTCCGGCGAGCGATCGAAGCGACGGTGTGGCCCGGGTCCCCCGGCACCGGCGACGCCGGTGTCCTCGACAGCCGGGTCACCGGGGCACTGCGGATGCTGAAAGTTCTCGACGGAATCATCGGCGAGGGACACGACGACGACATGCTGCGAGGTCTGCGGCAGGCCATCGAGGCCTACTCCCGGCCCACGCTCGATCTCGGACAGGCACGCGCGGGACTGACCCGGGCGATCGGGTTCTGGCGTTCCCGGCGCGGGCTCGGCCAGGTTCCCCGCGCGGCGACCGCGGGCCTGGACGCCGCTATTACGTTGCTGCTGATCGACGCCACATCCGAGCAGGTCATCCTGCTGTGCGAGCTGCTGGAGGCCCTCGCCGACGCCGGCCTCACCCGCGACCAAGTCGACTGGGCCGCCGACTCGATGTCACCAGCCGCTTTGCAGGCGTCGCTGGCTCGCCGCGCGTCTCAAGAGCCTGTCTGGCCCGACCTGGAGCTGCTGTTCGACCGGCTCGCCGACCGCCACGTCCTGCTGGTGCACCCGCGACGTGGCCTCGGCGACGCCGACGTCGTCGTCCTCTATCTGCGCCCGCCGGGCGGCTACCTCTTGAACCGCGTGTGGCTCGACGCCGAAGACCAGCGCACCCTCGATCGCCTGAGCGGCCGCCCGCTGTCCGGCTTGCGCTCGGTCAGCCAGGACGATGTGGACCGGCTCGCCGGCAAGATCATTTCGCCGGCCTTCGCCGAGGCCCTCGACCAGTCCAGCACGCAGGAACTGGTGATAGTGCCAGCCGGGGCGCTGGCGACCGTCCCCTGGTCGAGCGCGACCGTGCATGGCCGTTCCTGGACGACTCGCCCGATCACCGTCGCGGCGTCGATGTCGGTGGCCGCGGCCGTGCCGCCGATCGCCTCCGCGCGACGCCGGGTGCACGCGATCATCGACAGCAGCGTCCAGGGAGGAAAGGAGCTGCTGTCTGTCCTGAAGGAACACGCGACCGTCCACACGAAGCTGCCTGCGGCACCACATCCGGACGACGTCCTGGTGATCTTCGCGCACGGGACCGGCGCCGGTCTCGAGTACCGGTTGCACCTGCCGGACGGCCCGGTCGACGTCCTCTCGCTCGCCAGGGCCCGGCTGCCGCAGCGGGTCATCCTGGCGGCGTGCCGTTCCGGCGGGCCTCCGCCGGAGGCGTTCCCGCTCGCGGTGCCCACGGCGCTGCTCCTCGCCGGCGCCACCACCGTCGTGGCGGGCTTGTGGCCGCTGCCTGCCGCCTCGACAGCCCGGATCCTCGCCGACGCGCTGCTCGAACCCGAGAGCGGGCTTGCCGACGCGGTCCGGGCGGCGATCGGCCGAAGCGGCTTCACCACGGTCATCGACCGGGCCGGCCTCGCCGTCTTCGGACGCGACGATCGATGAGCCGCGCTCGTCTTCGTCAATCGAAGCAGGATTCGAACACCAAGGGCCGGTACACGGCGACTTGGTCGCCGTTGTAGCGGACGCCGAGCTCAGCGGTGAACTCGTACCCGGACTCCGCTTCCGTGAATCCTAGGGTGACCAGGAAGTTGTCGACCTCGTCGGGGAGCAGCGAGTGCCGCACGCCGACCTCGCCCTCGTCACCGTCGACGAGCAGGTCGTAGCCTGCCGAAGGAGCGTAAGCGGTCAAGTAACTTTTACGGTCGAGGATTCGTAGGCTGACGCGGGTCAGATTGGCCACCGACGGACCCGTGTTGCGCACGCGGACGTCCAGGACGACACAGCGAAACTTCTGGAAGACCTGCACGTCGTCGATGCTGACGGCGGTCGCCGTCGTCACGGCCGCAGACTCGAGGTCGAGCGAACCGATGTCCGCAGTGGCCTCGGCATCGTGAACCGCATCCGCGGCCATGCTGACAGCTCGCTTCGCCTGATCGAATTCGGTGCGGAGGCGACCCAGGTCATGGCGGTTCCCGGTCTCCTTGTCCACGGTCTTGTAGAACTTCAGCCCTCTGGGCTCCCACGGCGTGTCCCGTTCGTTGGGCCGCAGCTTGGCGACGTTCGACGTGCTGTAGTGCAGAGCGGCAGCCACATCCACTTGTTTGCCGAACTTCTGTTCCAGCTCGTCCAAGGCCTTACGGCCGGCCTTCTTCAACCTCGCCTTGGCCGTGTTCAGCCGCTCTGTCGCGACCTTGTAGGCGTGGCGGGCCTTCGCCAGCTCGTCGTCCGCGGTCATGCTCACCTCTCGAGGCTCAGACGATGTCGAGCCTAGGCGCTGCCGACGCCGCTTCGGCCGCGGCGACGATGGCATGCGCGTCGGCGACGTTGGCCACCCGGACGGCCACGGCCGGAATCGCGCGTTTCGTAGGCCGGGTCGTATAGACGGCGAGGTACTTGGTGGCCCGGTTGTAGATCGCGGCCTTGGCCTGGTTCCAGTCCACTTCCAGGACCTGCTTGCGCACGATGCCGACGAAGAGGAACAACAGCCGTTGGCGCACGACGCGACCAGGCAGGATAAGGTCCGCCAGAAGCGTCGACTTGCCCGAGCCAGCAGGCCCCGGATGACGGTAAAGCAGGCGATCCGTCCAACCCAGCCGCGCGAGCAGCTCGTCGCGGCTCAGCCTGGCGGGTTGAGCGGGATCACGAACGATGCTGAACATCTCGCGCGCGAGATGTTCAGCATCGCGGCTGACTGGGTCCTGGTCCGGGCTCAGCAGTGGATCGACGAGGAGGATCCCGAACTTGAACTCGAAGTCGCACAGGAATGAAACGAACGCGTCGTCATCAAGGCCGCTGCATGTCCGCAGCGCTCGCCACGCCGGCTCCCACTGCGTGATCTCGGATAGTTGCGCTAGTTCAGCCCATCGGGTGATGCCCGTTCGGCGGACGCGGTCTTGCACGGGCAAAAAAGCCTGCCCTTGAAAGGTGGCGAGACTTCGCGTCCCCGACGCGGTCGACTTCCCGATCGGCGAGGTCACCGTAGCCTTGGTGGTGGACGGGGTGTTATTAGTACATAGGCACACGACCAGCTTCCCAGTCGTCACTCCCCGTAGCCTTCGCCACGCCTGTGCCAGCTCGTGCAGTAGTGCCGGCCCGTCCTTCGAGGCGCTTGTCAGGTCAGCCCAGGTGTACGTACTCGGGTACTGGGACCCTTCACTTGAAGCGCGTAGCGCGCACCACCCGCACCGAACTGGAAGTCATCCGCGACGCCGGCGGCAGGATCCGCGAGTTGCACCCACTCAATCGTGGACATTTTGGCCAGCACGACACGGGCGGCAAGATCGTACTGGCCACCGAGCCGACAATCGCCCGAACTTCGCCCTCGCTTGGTTTCACGTCGCCGCACCTGCCTGCTGCCTCACGAATCGACAAGGCTACCGGCTCGCTGCCTCGATGCGAGGACGGCACGCCTTGACGCCGACCGCATACAGGCGCCAGATCTGCCCGGCCAGGTCTGGCTACCTCCTCATTTCGTGGCGGAGCGGTCTGTCCGCCAGATGCGTCGTTCAGCTGAGCGCCGGCTTCGTGAGTCACGATGACGTACGGCTTACCGACTTCTGCAGCGAAGCGCCCCCAGCCAGCCGCTCGGCGGAGAATTGTCAGTAGAAGTTGCGGGGCGTCACGTTGCGTCGCTGTCCACGTGGCAGTGCGTCCTGGCCGAGGCGGTCAGTTCGGCCGAGTTCGGCATCGGGGCGTTGATTACGCGGCACGAACGCCGGGCGGTTCGGGTCGATACTGCTGATCTCGACCGGGCCGCTGGGGCGCCGGGCGTGCATCGTCGGCCGGACCTTGCCGAGCTGGAGTGCTGCGCCGACCGCGGAGGCAATGGTGCGGCAGGGTTGGCCGGGCACAGCCCGACAATCAGGGCAGTGGTGATCGCTGCGTTCGGCTGGCGGCGTGCTTGTGCGTCGCTTACTCCTGGGGCCGCCCATCGGGGTGCCAACAAGACCGCGCAGACCGCGCTGACCTTTCTTCTTCACCATGCCGAGGTTCTACACCCGCGAGTCTGGGCGAAGCGTCGCTCCGACTCGGCGAGTCGGGGAGATCAGCGGAACGGGCGCACGACGGTAACGAGCGGCGTCCTTGCTACGTCATCGAGGGCAGCGACAGACGGTCGCACGGCAGAAGGATGTACAAAGTGGAAGCAGCGCGCGACGATCTCAGCCATGTGTCCGTACCGGACCTGCTGGGCAGGTACGCCGCCATCCTGCAGGAGCTGCAAGACCGCGGCGTCGTGCGGACCCGCAACGCTCCCCTGGGTGACTACGCCGAGTACCTCGCGGCCCAGGTCTACGACGGGGAGTTGGCCGCAAACTCGCTGAAGTCCTACGACCTGCTCGCCGCCGATGGCCGCCGGATTCAGGTGAAGGCCCGCACCGTCGCGCCGGACACCCGGGCGGGTGCCGTGTTCTCGGTCTTCCACTCCTTCGAATTCGACATCGCGGTGCTGATCACCTTCGACAGCGCCACCTACGCGCTGCGCCAGGCCAGAGAGGTGCCGGCCGCCGATCTCGAAACTGCCGGTCGGCACTCCGACCACGTCAACGGGCGCCTAATCAGGATCACCGCCGGCATTCGGCTCGGCGTGGATGTCACGGCGAGGTTCCGTGCCGTCGCCTCGCGGTAGCTGCCGGAGGTTGTGCGGTCTCAGCTCTGCGCCGGAGCGTGAACGAGGACGAACCGGCGATTCGTACGGTCCCAGCAGAACGCGTGGATCTGCTCCCACAACGCGGGCAACCGCCAGTGCGGCGCCACCTCCGGGGCAGACACCATCGAGTCCGGGAGTGCCATCCATGCCGATCAGGTAGTCGGTCGGCTCGAGTACCTGCCGCCACAGCTTCCATGTCGGTTCGCCGATGATGACGGACCCGATGACGTCGGAGGTGATCTGCAGCCCGCTGAACTCGGGCCGGATGGGGATGCGCCACTTCCGCTCGTGCAGCCAGTCGCTGGTGTAGGCGTCGAACTTCACCGCCCAGTCCCGCTGGTTTGGCGTCAAGGTCCGGTGCTGGGCCTCGCGGGTATACCAGACCGGTACGCCGTCGGAGCAGTAGACCCACTCGCGGGTGAACAGCAGTGCCCAGGGCGGGAACGCGCGGTCGTTGAGCAGCCAGTGCAGGTGCTCGACGGGGCTTTCGGAGAAGCACGCTATCAGAACCGCGCGGCCCGCTCACCCAGAGAATGTTCGCCAGCCGGTCAGCCGGGGTCATCGCGGTGATTCCGGGGTCCAGCCGGGCGGATGTGCCGATGCCCGGCGGCCGGTCGCAGAAGTAATAGATCAGGTTGGACTGCGCCGCTCCCGGTTCGCGCAGTTGCAGGATGGCGACGGTCATGACGCGTCGGCCAGGGCGCGGTAGAGCGAGGCGACCGACGAGTTCTTGCTGGTGCGGTTGGTCAGCTTCTTCGCGATCTCCGGCATCGAGGTATCCTTGTCCCGCAGGGCACGGACGAAACCAGCATGTCCTCGTCGATCACCTTCGGCCGGCCGCCGTGGTTGCCCTTCGCCGCGGCAGCCTTCGTCCGTGCCGGGTGGCCACCCTCGGCTACGGAGCACGCTCGTCCCATGTTTCGTCGATGGCGCGGATGATCCGGCCTCGATGCGTAACAGCGGCGCACCTCGCCGCGACCTACCAGCCGTCGGGTCGGGCGCGCCTGGAGGGCGTATGGAGATCGCGAAACTGATCGTGGCCGCGCTGACTCCGTTGTCCGTGGCTCTCATCGGCGTTGTGCTGACGCGGTCCATGCGCCGTCTCGAGCACAGCAACTGGTTGAACCAGAAATTGATCGAGAAGCGAATCGAAGTGCTCGGCGAGGCGCTGCCCAAGCTGAACGACCTGTACTGCTACTTCTCTTGGATCGGCACCTGGGCATCACTTTCCCCAGTGGATGTGCTGCAGCGTAAACGTGACTTGGACCGGCTCTTCCACGCCAACCGAGCGTTCTTCACATCATCCGCGTTCGACGTCTACGGAGCCTTCATCGATCTGCTTTTCGAAACATACGCACAGCCGGGAAAGGGCGCACGGTTGCGCACCGAGATGACCTCACACAACGGCAACCGAGCCGATGTTTATCCCAAGAAATGGGAAGAGGGTTGGAGTGAGATGTTCTCCGGAGTTCCGCGGACTTCGTCCCTGCTGACTGTCAAGAAGTGCTACGAAGGCTTGGTGATGACATTCAGCGCGGAGGTCGGCATCGAGCGATCGGACGCGGTCGGCCGATGATCGTCCAGTGGTGCTGCAAGGGAATGGCGAAGCTGCCCGAGCGCGAGGCGGAACGGATACTCACCGGCGGAACGGGGATCCGGTGCCGAAGCTGGCTCACTGTCGCTCCGAAACCCTTCCCGCTCGGCAAGAACCTCGACCGTTTGACTGAGGACAACCTCGACCGCCATGTCAACAAATACAGCGATCCCGACCCTGTCACCGGAGCCCCGTTCCACGACGTCACCCCGTTCATCTCTCTTTCCGCGGGGTGCGTGGATCGACAGGTGGCCATCGAACGAAATGAGACGCACTCCGCATTGCGTACCGCCTTAACTTTCGCGACAACGGATTATTCCCAGCCGGGACCGAACTGGCCACGCTGCGCTGGCTGGGTTTTCTACTGCTACGTTCTCACCGGCGTCAACCGCGCGGTCTCGATCCCCTCGGTGGCTGAGGAATATCGGGAGCTGAATCTCGGCAGATCCTACTCACGGTGGCAGCCCCAAGGCGAGGTGATGGCGAAGATCAACGTGCCGTCTAGGCAGATACTCTGTGCGGTGCACTGGACCCCATTGCCGTCAGGCGAGTCGAAATGGGACGAAGTCCTGTGGAACCTGAGGTTCACCCACCCGGCGGCATTGCTCGGCGAACGGAACATGTTGTGAGCCTGACGGACGAGCAGTGGGACGCGTTGGGCCTGGACAGGGTCGTGGTGCGGGACAGGGCGGAGTTCTTCATCGGCTATGCCGGCAGCGAGGCCCCGCTCTTCGACGTCGACGGCGTCATCGACGCCTTCCGGGACGGTCCGCTCGGCGACGAGACAGACCAGAAGGTCGCCAAGTTCACCGATACCGACGATGCCGGCCCGGCGGGCCTGCTTCGCCGGAGAATGGCCGAAGCGGCGGGTCGACCGGGACGCAGGCCGTGGGCCAGAACGGCGGAGCGAGCCGACGCGCTACGCCATGCAGCGCAAGCTGCCCTTCTCGGCGATACACGCGAGGGCAGGAACCTCTTGCTTCAGTCGGCGAGCCTGTACCGTGAACTCGGGCTTCCCTTCGGCGACTTCCTCTCCGCGGCGGCCGTCGGGCCGGGTGACGCCGCCTTCGAAGCGGCAGGGCAGCTTCGATCAATCATCTTCGGCTCGGAAACAGCACCGGAGGCGCGAAGGGTCGACGAAGGGTATTTCTCTCTTCCGCGGCGTCTCCTGGCACCTGCCCAGCAGATCGCGGTCCTCTTCACCGCGCTGTCCTCCGCCGATGGTGTCGATGGGTTTGGCATCGGCATCGATCTGCTCCGTCGAGCGAGTCAAGCGACCCAGGCGACGTCGGTGGGGGTGACCGGCCGGCCGGTCGCACTCTGGTGGGAGTGCGGTGTGCGTCTCGCCGAGCTGACTTACGGACGGCCGTCCGCACGAGATGACCTGCGAACGACGATCGCGGAGCTGGCCACCGCGCACGGCCAGGCACTGCGAACAGCCCAGTTCGACCGCTATCACTGGCCCCGCGCGCTCTCCAAGATGGACCTGGTCGACCTCGACTTGACGGGCCTGACCGCGATTTCGAACCGGGTTCTGCGCCAGCTCGGCGAACCGGAGTGGTCCATGTTCGAAGACTTCCGGGACTTGACCCCGCTCTCACAAGTCTCAGTCCAGGTCGGGATCCGCCTCAGCGGTCCCGGCAGGCCCCGGACTCCGGCGTCGGGCCCCTCGCCGTCTCCGGAGCCGACGCCCGGCCCCGCCGCAGCGTCCGACTACGTCCCGGAGTCTCGATCCCCGTCGCTCTGGGCACGGTCGTGACGATCGGTGTCGATCCGGACGTCGACTCGTCTGCGGGGTTTCGATGCCGGACTCGCGTGGGGTGAACCAGGAAGGTTGTACCTGGATCTGATGGCCCGGACGATCGGAGTCAGGTACCGGTAGGCTATGTCGAAATTGAGCTCCTTTTGGGGGACGATCGTGTCCTTGAACGAGAAGATCAGGGGTTTCACTCGGGCATCCTCGCCCAGGACGGCTGCCGCATCTTCGAGCAGACCCGCCAGCGTGAATAATTCAGGTGGCGTGACGCGATCGTTACGTCGGTCGGCCGCAGAGAAGATGTGCGCGAACGAAGCCAGCTGGTCGGCAGTTTCTCTGGCCAGTTGGCGCAGTTCGTGCGCATCTCGTTCGCGCGGGGACACGGCGGCCCCCTCTAGGTGGCGCGACGGCCGGCTGCCGAACATGGTAGTGGATGAGGCGCCCGTTCTGGCGGAGTGCTCGGCGAGGTCGGGCCTCGCGCAAACCCTCGTGCCGCTCGTCCAGTTGGTCCATCGCTCCTGAAGGTGGCACAAGCCGACTCGGCTTCTAGACGTCCCGTCGGCTCGTCCCCGGGCCACGCCCCCCTCGGGGTCGGCTCGTCGTCGATGCCGCTGCCGTCACGGCGCAGTGCCTTGCGCACCAGTTCGACCGACTGGTTGTCGAATTTGTCCTTTAGCCACCTACAACAGCTGTGACCTCGGTGTTGTCAGGATTCGACCAGGTTGACCTCGGTGAACGCGTTGAGAAACTTTCCGGCGGTCAGCCGTGCCTGGGTGAGCTGCACCGACACTCCCTGCTCGTCGTACCAACGGCCTTGTCCATCGGCCAGCGCCACGGCGAACGACCGCACCGCAGTCTTGAGCTCGTCGAGTTTGGCGGCCGTGATCACCCGCATCCCGGGCACTGGCGTTCCCTGGTGATTCACGATCCGGCTGGGGTGCACCATGATCGGGATGCTGGTGATGCCCGGGATGCTGGTGATGCCCGGGTGGTTGTCCTGGTCCCAGCGGACGGAGCCGCCGAGCTGGTCGACGTCCTTCTTCGCGATCATGTCGGTGGTGCAGCCCGTCTTCATCTCGACGACCGCGTGGCGGTCACCGGCCAGTGCCCAGAGGTTGTCCGGGCCTTTGCCATACAGCTTCTCCGGCCGGGTCGACGTGAACCCCAGGTGCGACCCGAGCCGTTCCCAGGCAGCCTCGGCCTGGGGTGTGCGGTCCTCGTCCCACTCGATGTCGGCGAGGGTGGCGTTGATGCCGAGCACTAAGACCGCATCTCGTTTGGGCGTGTTGCAAGGTAGGCGATATCGTTGATCAACGATGGACGATGTGGAGAAGTGGTGCCCGGAGCCGTTGTGGCTGCTGGCGCAGCCGTTGCTGCCCGAGGCGCCGCAACGCCACCAGGGCGGTGGTCGGCGGCGTTTGGATGACCGTGTGGTGCTGGCGGCCATCCTGTATGTACTGCAGACCGGATGTGCCTGGTCAGCGCTGCCGGCGTCGTTCGGGGTCAGTGCCCCGACCGCGCATCGCCGGTTTACCGAGTGGGTCGAGACGGAGGTGTTCGCCCGGCTGCACCAGGCGGTGCTGGATTTGCTCGGCTCGGCCGGGGCGATCGACTGGTCACGCGCGTCGGTAGACGGCATGCACGTCCGGGCGGTCAAAGGGGGGACCTGACCGGCCCGAGCCCGGTCGACCGGGGCAAACGCGGCAGCAAGATCCACGCGATCAGCGACCGCAGTGGTCTCCCGCTGGCGGTGGGCGTATCCGCGGCCAACCGCAACGACCACCTCGAACTGGAGGCCGTCGTCGATGCCGTGGTCCCGGTCAAGGGGCCTGCCGGCAGGCCTCGTCGCCGACCACGCAAGTTGCACGCGGACAAGGGCTATGACTACCCGACCTGCCGAAAGGCGTTGCGACGGCGCGGCATCATTGCCCGGATCGCCCGCCGGGGCATCGAGTCGCCCAAACGGCTCGGCCGCCACCGGTACGTCATCGAACGGACCCTGGAGTGGGTTTCCCGGTTTCGCAGGCTGGCACGCCGCTACGAACGCAAGGCCGCCCACTTCACCGCATTCACCCAACTCGCCTGCGCGGTGATCTGCTACCGCCGAGCCATCAAACTGGACCTGCTCACCCACAACAACCCCAAATGAGATGTGGTCTAACTGCACGCCGTCGGTGCCGTACTCCGCGGTGAGGAAGGCGGCGGCGGCCTGAGCCTGCGCGACGACAGCCTGGACTCGCACAGTCGTTACTCCGACCAGCGGCTTGAGCAGCGCTCCGTTCTCCTGGACGGCGAGGCCTTGCTGCTGCTGGGCGAGCTGGGGGGGTGACGTGGTGCAGGTAGCTGGCCTTCTGTTCGCAGCAGCGTGTCCTCGATGCCGTTGATGGCACGCTGGATCTCATCGGCCGCGGCGCTGTATTGGCCGGCGGAGGCCAGGTCGAACGCTGCGCGGATCGCGATGGCCTCCGGGCGGATCGTCCCGGCGTCGAGGTAGCGGATCTCGGCCAGTGCGCGGCGGCTGCGTTCGACCCAGTTTGGGTCCCGATCCAGGCACGCAGTCAATGCCGATCGGACGGCGTCGAGCCCCTGGCCCTTGAGCTGGACCGCGACTTGGTTACTGAGGTCGAGCTGCGCGCGGGTCGCCGGGGAGAACAGCTTCTTCCAGTCAGGGTCGCGAGTGGCCATGGCCAGCTTCGAGCCGACCAGCAGTACCGCGCAGTGGTCGTCGCTGTCGCGGACCCCGCGTCCCATGCCCTGCTCGATGCGCTGCACTTCGCGGATCCGGCGCGTGGGGCTGTTGGCCAGCGCGGCGGCCGCGCTGCTCGACGCCGTCCATCGGTTCGGGAATGCCATCGATGATCAACAACTCGCAGGCTGTTTAGGTAAGTCGACGCCGTCGTACTTGTTGATCAACACGACAACCCCGACGTGGCGTGCGCGCAGCTCGGCTACGCCGGCGCGGGTCCCGGTCAGAGAAGTCGGCGTCACCCTGCACCCGGGCCGTCCCACGTGCACAGGGCTGGCCCGGCGCTTCCCACGTCGTCAGACCGGTCCATCCCAGCCGTACCAGCTCGGGTGGGCCGAACGCCTCCGAGCAGACCGTCTTCGCCGGCATCTGCAGGTGCCGACTCCGGCGTCGTCCGATTGCCGACCTCGTGCACCGAACTCGTCCCGCGCAGGCGGGGACGGTCCCGGTCCCGCCAGTGCCGAGGTGCAGACTTCGGTTCCTCAAAAAGTCGTATGCCCTGGCGTTCGATCCGCTCACGACACACCGCAAGATTACATGGACATTGACTTACACGGTCGCGTTGCGTGATGTTCTCCCTTCACGGAAGGCTCTGACGCATGATGACAAAGCACCCTTCGAACTCGGATCTCCCGCACGAAGGCGACCTCAACCATGGCGAGGAACGCGATCGACTGACGCGACCGGCTGTACGACCGATTCCGAAGTGGGTCGTCGTTACCGGTGTCCCACTGATGATGGTCATCGCGATCAGTGCCGCATGGCTGCTGTTGAGCACCGGAGCGACGAGAGATCAACTGGATGCATTGCGGACTGCTGGCACCCTAGGAGTCGGATTCGGTGGCGTAGTGGCCCTCTGGCTTGCCGTTCGCCGGCAGAGGTCTACCGAACACGACTTACTCCAGAAATACCAAGCCCACGAACTGGCAGAACGAGTAGCGGCTCAGAATCAGGCCGCCGCCGACAGAGCTGCCGCTCACGCCGAGCACGACGCTCGTGAGCGCCGCCTCACCGACCTCTACCTCAAGGCTGTCGAACACCTTGGCTCCGCCCACGCACCCGTGCGCCACGGTGGCCTCTATGCCTTGGAACGCGTCGCCCAGGACAACCCGAGTCAGCGGCAGACCGTCGTCGACGTCGTATGCGCATACTTGCGCGCCCCTTACACCCCGCCGAACACATCAAGAGCTAGCAGGCTCGGACTCAAGCGACCACTGCAAAGCTCTACCCGTAGTCGGGCGACCAACTCAGCGCGCGCACGTGAAACAACAACGACGTCAGCGCATACTCGGACCATCAGCGCATCACTGGAGGAGCGCGAAGTCCGTATGACCGCTCAACGACTGCTCAAACGTCACCTCTCCCTCGACATCCACGACAACTCAACTGGACTGTTCTGGGACAACATCGACCTCGACCTGGCTGGCGCCACGCTCGTCAGTTTCGATTTCCGCGGCTGCCGAGTCAAACACTGCACCTTCCTCCATAGCACCTTCGTCGGCCCGGCCCGATTCGACAACGCAGTATTCACCGGAGAGGCTTCGTTCGCTAGATCAGCGTTCACAGCTGAAGCGCGTTTCTCTGGCGCAACTTTCGCGAATGAAACATGGTTCAAGGGCGCGACATTTACGGACGGCCCAATATTCAACGGAACCACGTTCTCCGGAGAGTACTTTTTCCAGGAGGTCAACTTCGCCGGTAACGCACAATTTGACGGCACACTGTTCACTGAGGGAACCCCCGTTGAGGTGTCTGCCCATCTTGACGGGCAGAGCAGGTCAGCTTCGCCGTGACGCCGGTAGCGGATGACCCACCTGGATGCACATTGAGGGGAGATACCCATCTCGGCGACGACATGGGCGATCGGGTCGAGCCTGGCAACGCACAAGCCAGCGGCAGCCCTAGACAGACAACGGGACATTACAGTGTAGAATGGAATGACCTTTTACTCGGCGGACGATTTGCCGCACTTCTCATACTGCCGCCGAAAGACCCGCCCCTCGCCTCAGGTTCGGCCAGCCGTCGTAAACGTCATGACCGATAACAGTTAGCCAGGACAAGCTCGACGACCGCGCGTTAGCACTCAGCACGGCGACGACCTCGCTGCGCACCGGCAGCCGCTGCGGTTTCCGAAGCTCAGTCGGCGGAGCGGAATCGAAGGTTCAACGACCGGCCGACCACCTGGTAAGACGCCAGGCCGCCTACCGAGAATGGGTTCGGGAGCACCCGGAGCCGCATCTTGTCCGGATCAAGGACGTTCGAGATGAAGAGAATGTGATACTCCTCGTGGGGTCTCAGTGCATTCGCCCGGCGGACCTCCGACTCGCCGAGGGTGAACTGGCGAGCATTGTCGGTTGTGGCCTTCACTTCATAGAGCAGCGTTCGGTCCGGGAGCGTGACGAGAAAATCGTATCCACACGAATCGTTTCCCTTCCCATCAGCGAGGTATTCGGCGCGGTAGCCAGAAACCCACGTGTCCTCCGGTTGCAGACCGAACTTCGCATTCAGCCATTCGCCAGCCACAATTTCACCAGCGAGCCCGATCAACCTGGTCTTTTCTGCCGACAGTACCGGTGCGCGCCACTCTCCCGAGCTGCTTCCGCTGACCGCAGAGCTGCTCGGGGGAAGGGGAGCCATCCGGTCGGCTGTGGCGGAGGTGTCAAGAACGCCTTGCGGGACGCTTTCGCGGACCGCCCGGATCAGGCTGTCGCGGTCCTCTGTACCGGTGGAATAGGTCTTTCCGGCGTAACGAACGGTTTCAGTCCGACGCTTCGCCGTATCGTGGCCGGCGTTGAGCCGGGACTCGGCGGCCTTGAGATCTCCGTCGGTCAGATCCAGCTGCCGGGGCTCGGTGGTGGCGGGCATTCCGACCGGCCATTGCCCGTGCTCGCCCAGCCAGACCACCACCGCGCTGGTGCGTGGCACCTCGAAGTCCAGGAATCCTGTTTGGACCATCTTTTCGAGTGTGCCGGCGATCTCCGCCGGACGCGCGCCAGTGCCCGCGGTGTTGCGTTGCAGCCACGCCTCGATGACGATCCGAGCGCGCTCAAGCGTGCGCATTACGGCCCGGCGTCCTCGATCACGGAGCTCGTCGACCGGCGGGAGCCGATCTTTCCCCGCAAGTGGCTCACCGACGGACGCAAGCCACAAGTCGAGACGTGCCTGGACGACGTGGTCAGGCAAGTGCCAGTAGGTGTCGAGCCAGGTCGAATCGGGCTCCAGACCCGGCAAGTCCCGCAGACGCAGATATTCGTCGAGTGGCTCGCCGCGGCGGAACCTGGCCACGAAGCGGTCCCGTAACTGATCCTGGAGCTCCGGCCGGTGCCGTTGCAGGTAGGCGTCGAATTGCTGCCGGTGCCCGATGTCGTTGTGCAGCAGCGGCAAGTTCACCGCCCGTAGCCCGGCATTGGCCTGGGCCAGTGGAATGTCGAGCTGCCGGGTCGCGTCCAAGAGGTCGTTCTGCCCGGCGAGTGCCAGGATCTCGTCCGCGTCGAAGCCGCGGCGACTGAGCCAATCCAGCATTTCCTGTTGGTCGCCGATACGGTCTCCCTGGAGCTCTTCGGCGATGCCCGGATCGAGGCAGGCGAGCAGCCCCAACACCGGCGTTACTTCGAAGCGGGTCGACGCCGCATCCCCGGCGAGGCTCTGCAGCTCGGTGACGGGCAGCTTCAGCACGACGGCCAGGTCGTCGAGCGTGGGGGTGCGGTCGCCGCATCGCTGGGTGAGGTCAATGAGCGCGAGCCGGACGCTGTCAGCGATCGGCGGGCCCCCGCGGAACTCGGCCAACGCCGCGGCGGCGGACTGGAGCACCACCCATGGCTCGCCGGTGCCACGAAGCGCCACGATCACCGGGTCGCCTTCTGGCGAGACGACGCGCATCGAGGACGGCGCGAACTCCTGGTCCACCGGATGTCCGTCGATGACCGCGGTTATCGAGTCCGCCAGGACCAGCCCGACGGAGTCCCGTAGCGCACCGGCGGTCGCGCCGACCGTGATTCCCGCCGCCGGCAGGGCCTGACGACGCCGGTCCGCGATGGCGTCGACGAGCAGCGGAAGCCAGTCGCCGCCGAGATCAGTCAGCGGCTGGGACTTCATGGTCAGCGGGTCTGTTCCGTCCGCCAGGACCTGGACGGTGGCGGCCGACGCAGCCCGGAGGCGGCTGACTCCGTCGCTCACCAATGTCTGACGGACCCGCTCGGCCACGCCGGGACTGCGGACCGCGAGCATCGGCAGCGGAGTCTGGATCAGCAGCGCCGCCTGCACCGCGCCGTCTTCGTCGAGGGTGTAGACCGCGGGCCCCTCCTGATCGAGGTCGAGCACGCCGAGGCTGCCGTGCACGGACACGATCACCTCGTGCGGTACCTCTTCGCCACGGTCGGCAAGGTCTCGCCAAGCCTGCTCGTAAGCGTTGCGTACTAGCGACATCCGAGGTCCGCGCAGCCGGACCACCGAGGTGAGCTCCCGCAGTCGGTCCGCGGCGGTGCCCGGGTCGTCCCAGAACCGGGCGCCCAGCCTTTGAAGGTGTACGCGGACCCGGTCGGTCAGCAGCGACCGGAAAGCCGCCGGGTCCGCGCTGAGATAGTCGGGTGTGTCGGTGTTACCCACCCACCACGCGTCGGACATCGGGCGGAAGAACTGCTTGCCGCGGTCCCCCGGCGTCGTCTGCGGGATCCAGTCGGCTCGGACCAGGAACGCGGCCACGAACGTCGGCCAGGTGACCCGCACGCTGTCGGAGGAGGCTTGAAAATACGTCCAAAGAGTGGTGGCCGGCCATACTTCAAGCCCGTGCAGCACCAGCTGGAAGTAGAGCCGACGAGCCGTGTCGTCGAACTCGGACCACTCTTCCTGACCAGGCAGGTATGCGATTCCGCCCGCCGGCTGGTATCGGGTGCTGTCGTAGCTGGGCTTGCCCGAGTGTCGGGCGGCCAGCTCACGCCACGCCGCTTGGGTCGCCACACTGATCTCGATAGGGAAGACTGGGACTGTCCGCGGGTTCTTCAGGGTCTTGCCCTGGAGCTGGAAGCGACTGGCGCGCACGGTGAGCGGAACCAAGCCGTGGCGCACGCCCAAGGCCTCGAAGAATGTCCGCACGTCGTCCAGCGTCGCCTCTCCCAGCTCCGGCTTGAACAACAGACTCTGGCCCACCGCGGCCAACGTCCCGGAAATCAGTGCGGTGGCTTTCACCAAGTCGGCCAACTGCCGATCGATCTTGCCCGCCGGTCCGCCCCAGCCCGCGTCGAAGTACGCTTCCGCGGGCGCCTTCCAGCCACTGCGAGTACGTACGAGAAGACCGGCCCGGCCGAGCGCAGTGGCCCGCCGCTCCGCTGGGGTGTCCTGCCACAGATCGAAGGCGAACCGGAGACAAGCGGAGCGGACCTCCTCGGCTTCGGTGTCGTACATGACCTTGCCGATTAGGTCGAGGACGGCGTCCGTGCGGTACTCGCGGACGATCGCCTCGAGCCAGCGGCGGCCCGGCCGCTGACCGCGCTCGTCGCTCCAGTTGATGTCGGCGGGCATGAAGGCCAGCCGGTCACGTACGACCTCCGGAAGCTCAGGCAGCTCTCCCGCCTCACCGCGCACCGGGCCGAAGTAGATCATCAGGTCGTCGTCTTCGATGCTGGTGCGGAGGATCCCCCCTTCGGTGAGAAACACCCGATGGCCGCGGATAAGTGTCACATCGGTCAGCACGACGCTTAGATCGTCGTAGAACCCGGCCCAGACCTCGTAGGATTCTCCTCGTCGGAGGAGATCGTCGGCCAGGGTCTCGGCGAAGCCGGCCAGATCGGCTGGCCGCGCCTCAACCGGGTGGTCGGTGGCTTTCGCCAGCTTCCGCAGCCGTCGGAGACGTTGTTCGTCGATCGAATAGCGGATCAACCTGGTTTCGCCGGCGGCCGTGACCGCCTCGGGTGTGAAGACGGCCCCGCGGTACGACCACAGCAGCGCGGACTTGAAGGTCAAGCCTTCCCCCTGGTGCTGCAGCGGCGGAAGCACCGGCAGGTCCACGAGCTCGACGCCGAGCGCCTGCAGAGCGGCGATGAGGCGCTGCGTCCAGCCGGGCGCCCAGCAGACCAGGTCGAGCGGCACTTCGTCCGGCAGCTCCAGATCGCCGCGGCAGGCGGCGACGACCGCGTCCGCGCACAGCGCGGCGATCTCGGCGAAGAGGAAGTCGTTCAACGGAATCGACTCGTGCACGTCCCGCCGGTCAAGCCGGGTGAAGAACGGGCCGTTGACCAGTGCGGCGATCGGGCATGGCGAGCCCGGGCCGAGCGGCAGGAACGTGTAGACGCGTCCCTGGGAGAGTGCAGCTCCCAGCGGCACCGCCACGCTGACCTCGGCCGCGCCCTGCCAGCCGGCCCAACCGGAGCCGATGGCGTTGTCGTCGAGGCTCGCCCGGATCGCGGCCCGTATCCCGGTCTCGGCCACGACCCTCTTGAGGATCACGTACTCACGCTGTTCGCCCAGGTCGATGTGCTCGACGGACAGGGTGCTGGTGCCTCGCCTTGCCCGGGTGCTCCGGGTCAGGCGGCGTCTGCTCTCGGTTTCGCCGGCCTGGCTCCGGACCACGATCTCCGCGACGCGCGTAAGGAAGAGGTGGAACGGCACTTCGTCGTGCGCGAGCTCCTCGAGCTGGTCCCGCGCATGGTCGCGGGTCGAGGCCGAACGCAGCGGGAGCCGGACGACCGTCGAGTAACCGCGACGGGCGAAGTCCTCGACCACCGTGGGAGTCTCGAAGAGCGGAACCGTGATCTTCAGGGTCGAAACATTCTCCCGCAGCTCATCCGCCAGGCCCGGCCAGTTTTCCTTCGACCGGGCGGCCAGCCCGTCGAAGTCGTCAGGCCGGCCGAAGCGGAACCGGAAGCCGTCGAAACGCCCTGCTCCTTCGTGCCGGGCGCTGTACACCTCCGGGCAGTCGGATAGCTGCAGCACGCTCTTGAAACCGACCCCCTTGTTCCCGATGCCTTCGTCGGGCCGTTTGCTGCTCCGGGCGATCAAGCACATCGACCGGAAGTTCTCCTGATCGAGCGGCCGTCCGCCGTTGGCCGCGTATAGCACGCCGTGTGCGCCCTCGTTCTCGTCGAGGAGGAACTCGAGCTTCCCATCGGACCGGCCGGAGTCGTGCGCGTCGTGCCCGTTCTGCAGCAGCTCGACCACGGTCCGCCCGTCGTAGTCCGCGGCGATGATGCTCTCGATCGATTCCTTCTGCTCGCGGGTCACCGGCTGCTCGTACTTCGCCCCGGCCAGGTACATCGCCACGACTGAATCGGCCTGCTGCAGCACCAGCCGGGTGAGGTCCTTGGCCAGCTCGACAGGCTCTTCGATCACACATAGTGATCGAAGGAGGCGCAGACGGCGTTACGGCGCCCGGTCACTGCGTCTTACCGATCGTCCCGTGCCGAGACGATGAGACGCTCGTGAGATAGGCGGACCCGAGGCCTAGAAGCATTGAATCTCGTCCGGCTCGGTGGTCTCGCGGGGTGCAGTCTCGGGGATCCTGCGCCGAGCGAACACCGTCAACAGCGCAACGTCTACCTCAGAACCGACGTCAGGAGCATCGCTCTTCGCGAGCGACAACGAAACTCGCCTCGGCAGCAACGTGAACAAGAAACACTGTTTCGAATGACAGACTTGCATGTCATCAAATTGTCGTCCCTGTACACGCGGGGCTGGTCCCGTGCCGTCCGGCAGCTGGACGACCTGCTCGCCGTTGTCTCCGGACATGCGGGGCCGGTCCTCAGGACGGCCGCGAGCGGTATCGAATAGTCGAGCCGTCCCCGCACCCGCGGGGCTGATCCCGGGTTGACATCAAAGGCTGCGCACCAGCGCAGGTCTTCCCCGCAAGTGCGGGGCTGGTCCCTCCGCAGCCAGCTTCTTCAGGTCGTCCGTCTTGTCGTCTCCGCGCACGCGGGGCTCGTCCGCGCCGAGCAAGCGAAACAGCGGCGACAAGATCGAGTTGTCGCCGCACAGGGCTGGTCACCCACCCGACTGCGCCAGGTCCCGTAGAACGGGTCACCCCCGCAGCCTCGAGGCTGGCCCTATCATCGACCCCGTAGCTGCTGGAGCGCCAACAGTCCCCTCGTCGCACGCGCAGGCAGATCCTGACAAGTTGGGCGATAACTTCAAGGAGGTAACGAGCGTCCTTGATTACCGCCAACTATTTCTCCGCAGCAGAGACGTGTGGGTGCGACGCAGTTCCTTGCGTCGCGCCGACCGTGAAGCATCCGGAAGACGCGATGACCACCGGTCTGGCGGGCGCTCACTGGAGGGTGTCACGGTGAACACCGAACAACTTCGTCGACTAGGCAAGATCAGCATCGGCAGACGCTGCGAACACCCGAGCCAAACTGAATAGAAAACACTGTTTCACTTGGTAGAGTCGCAGGTCAGCAAGAGGTTTCCCCGCGAACCCGGGGCTGGTCCTGTCGTGTAGCGGGTGTCGTCGTCGTTGGGGACGTTTTCCCCGCACGCGGGGCTGGTCCCTGCCCGTGGCGGAACCTGATCGTCACCAAGCCGCTTCCCATCGCACGCGGGGCTGGTGCCGCGCCTTCGTCCCAGCTGGCCGGCTCGACGATATTTTCCCCGCGCACGCGGGGCGGGTCCCAGGGAGATCGACACGTCGGACAGCGTTTCGCGGTTCCCGCGCACGCGGGGCTGGTCCCGGAAGCCGGTTGAGCTTCGCGCCGCACCGTCCGTTTGCCCGCGCACGCGGGGCCGGTCCGCAGGCCGACTACGAGAAGCAGAGCCCGCAGGAGCTCCCCGTGCACGCGGGGTTGGTCCGATCCCGCAGTAGCGACAGGTGTCGCCGTCGCGGTTTTCCCCGCACGCACGGGGCTGGTCCGCACACGATCGGCGGTTTCACCCGACCTTCGCGGTCGTCCCCGCGCACGCGGGGCTGATCCCGCATTGGCTAGATTGTTCTGGAAAGTCTGATCGTTGTCCCCGCGCACGCTGGGCTGATCCCGTCTCGAACGTCGTGGGCGAGACGACGTGCTCGTTGTCCCCGCGCACGCGGGGTTGGTCCCGACTTCAAGCTGCGCCTGGTCACCCTCGGCGTGTCGTCCCCGCGAACGCGGGGCTGGTCCGCCGTTCGGGTCGCACTCGTACGTGGGCAGATCGTCGTCCCCGCGCACGCGGGGCTTGGGTCCCGTCACCTGCCCGCCGGGCTACACCAGCCTGTTGTCGTCCCCGCGCACACGAGGCTGGTCCGGACGGCGTCAAGAACTGGTACGACGAAGTGGCAGTCGTCCCTGCACACGCGGGGCTGGTCCCTACGTGTACGTTGGCGCCTACGGAACAGGAACGTCGTCCCCGCGCACGCGGGGCTGGTCCCGCTCGGGCAGCTCAACCTCGCCACTGTCTACCTTGTTCCCACGCACGCGGGGCTGGTCCCTCGATCGAATGTCCGAGGAATTTGACGCGGCCCCGGCACCGGCTGTCGAAGTCGTTGCTGCGGCAGGGTTGCTCTATGACGGCACTGCATGGACCGGGGCACTGAAGCCTGGCTGCGGTCGCTGACCTTTGACCGGGTCGGGGTCCGGCTGGCCTTCGAGGAGGCCTTCGACGCGGTGCTTGCTACGCGGGCTCAGCGGGCCCGGCTGGACGCTGCGATCACCGAACTGGCGGCGCCCCCGGTGTTCGCGCCGGTTATGGGGCGGCTGGCCTGCCTGCACGGGGTAAGCACGCTGACCGCGTTCGGCCTGGTGACGGAAATCGGGGACTGGCGGCGGTTCACCGGTGCGTCGATCGGCGCCTACGTCAGTCTGGTGCCCGCGGACTCTTCGAGCGGTGAACACCGTCACCAAGGAGCGATCACCAAGACCGGTAACTCCGATGGCCAGCGGTTGCTGGTCGAGGCCGCCTGATACCACTGCAAACGCTACCGGCTCAGCCGGGAGCTGATCCGCCGCCAGGACGGCCAACCACCGGCGGTCCGGCAGCGGGCGGAGGTCGGCAATCGGCGGCTGCACTGCCACTGGACTCGCTTCGAAGCCCGCAGCAGACGCCCCGCCGTCAGCGCGGTCGCCGTCGCCCGGGAACTGGCCGGCTGGTGCTGGAGCCTCGCCACCCATGGAACCCGACACGGGCTGACTCCCCCGAAACCGCCGGCGGGAGACCGGCATGCGCAGACAGGCGCGAGGAACGACCCGCGATACAGCGATGAGCAGCACCGTCCCCAGCGAAAGTGCAATACTCGCCCCAAGACAGGTCAGCAAGTGTTGTCCCTGCACGCGCGGGGCTGGTCCGGGAGCACTCGCATGACGACCACGGAGCCGGCGGTTGTCCCCGCACGCGCGGGGCTGGTCCCTGGTTGATCCGGATGTCCCAGTCGTCCACCGCGTTGTCCCCGCACGCGCGGGGCTGGTCCCACGGTGGCGGTGGCCTGCTGATACTGGGCGTCGTTGTCCCCGCACGCGCGGGGCTGGTCCAGACGGTTGGGGCAACCTGAAGGCGGCCGGCCTGTCGTCCCCGCACGCGCGGGGGCTAGTACTACAGGGCTAGATCTCTAACATCTGGAGCCGGAGGCGGCGTCTGACGTGGTGTCGTCGGGCGTCCGCCTGGTGTTCGCGGCGCCAAGCAGACCAGCGAAGGCCGTGGTCGATGGCGTGATCATCTTTGTCGGCGAGGTTGAACAGGTGTCGGATCTCGGCGATGGTGAGCGCGATCAGGTGCCGGGTTCGGGTGGTCAGGGTGTCCGTTCTGTCCACAGGTGGAGTTCTTCTTTTTTTTGCTTTGTGTCTCATGACTGCGAGGAATGCCATGGCGAGCATCGAGAGGGTGATGTGCCGGTACCAGGCGTGGTAGAGGCGGACCTGGTAGTTGTCGAGCCCTGCTTCGTTTTTGGCTGCTTCGAAACATTCCTCGATCGGCCAGCGGGAACCGATGACGCGGACCAGTTCCGTCAGCGGTTCCCGGTGCGGGTTGTAGCAGTGAAAGTAGGCGATTTCGCCGTCTGCGATGTTCCGCCGGAACACATACTGGTGACCGTCGCCGGCGTCGACCAGTGCCCAGTCGTAGGTCCGGAAGCCCTTGGCGCCGATCCCGCAGGCGCGGCGGGACCAATCGTGGGGTTTCAGCCGTGATGCGACATGTTTGACCAGTGTCTCTATGCCGGTCGCCGAGGAGATAGCGCCGGTGCTGGTGTCGGTGTTCTTCGGCACGGCCATCGCATAGGCGATTCCTTCGGTTTCCAGATACGAGCGCAGTCCCGGATTCTGCCCGAATTCCTCGTCCGCGGCGAACCAGGCGAACGGCACCCCGGCCGCCACCGCCCGCGCGATCATGCCCTGGACCTGCTTCGGGCGGGTAGCGAACGTCACCTTCTCGGGCACACGCGCCTCGGCTCGGCGACCGGGATCGGCGCACCATGACTCAGCAGGCAGGTACAGTTCCCGATCAATGAGTACCCGATCGCCGGCCGTGTTGACGAAGGCCAGAAACACACCGATCTGACAGTTGTCTATCCGACCCAGCGTCCCCGAATACTGACGTTGAACACCCGCTGACTTGTCTCCCTTCTTCGCGAACCCGGTCGGATCCGCGATCAGCACGCCACGCGGGTCAGCGAAATGCTCCATCGCGTACGCGCGCACCAGATCCCGTGCCTCATCAGCGTCCCACGGAGACAGGTTCAACAGCCGCTGCAGGGCTTTCGGCTCCGGGTTCCCGGAATACTCCGCGATCGTCCAACCGTTCTTCCGCTCCAGCGGAGCGATCAACCCACGCAGATAATGCCGAGCATGCGCACGTGAATCCGTCCGATAGAACAACCCGTCAAGCCGCGCGCAGACATCCCGGAACTCTTGATCCCATACAGCCAGATCTTCCCGAGTCACAGTACCTGCAACCTCGCACCGCGCAGCAGAAGGAATGGTCACCGGCAAATAGTCGCACAACCCGCGATCGGTATCACGTACCGACACGCAAAGATCTAGCCCTGTAGTACTAGGGCCTGTATCGAAGTTGTCTCCGGCAGGTTGAGCTGGAGTTGACCGTGCTGGGCGTGTCGGCGGCCGAAATAGGTGAGGTCTCCGGTAATTGGTTCGTCGACCAAGAAGAACCTGAACACCGGAGACCTCGTGGACACCCTAGCGGTGGCGGGGCGGTTCGACCTGACCGACGCTCAGTGGGCAGCGCTGGAGCCGTTGCTGCCCGAGCCGAAGCGGCCTGGGCGACCGTCGATGTGGACCAAGCGGCAGCTGATCGACGCGATCCGGTGGCGGGTGCGTGCCGGCGCGCCGTGGCGCGACATCCCCGCTGGATATGGCTCATGGGCGGCGGCATATGGGCTGTTTCGGCGGTGGCAGCGTGATGGCACCTGGAAGCGGATATTGACCGCGTTGCAGGCGTTGGCCGAGGCGGCGGGGCGGATCGTCTGGGACGTGAGCGTGGACTCCACGATCGCGCGGGCGCATCAGCATGCCGCAGGTGCGCGTAAAAAGGGGATCTGCAGGCCGAGCCGCCAGGCGGGGTGACCGCCGAGCCGGATGATCATGCGTTGGGCCGGTCCCGCGGTGGGTGGACCACGAAGTTGCATCTGGGCTGTGAGCAGGGTCAGAAGCCGTTGTCGATCGTATTGACCGCCGGGCAGCGTGGCGACAGCCCGCAGTTCATTCCTGTCCTGCGTGGTATCCGGGTGCCCCGGCTGGCCGGTGGTGGGCGGCCGCGCACCCGGCCGGATCGGGTGCTGGCGGATAAGGCTTACACCTCTAAGGCAAACCGGGCTCACCTGCGCAAACGTGGGATCAAGGCGACCATCCCGAGCAAAACTGATCAGGACGCGCACCGCAAGGCCAAGGGGTCGAAGGGCGGCCGGCCACCGGCTTTCGACCCCGAAACCTACAAGCAGCGTCACGCCGTGGAGTGCGGTATCAACCGGCTCAAACGCCACCGCGCCGTAGCCACTCGTTACGACAAACTCGCTGTCCGCTACGAAGCCACCATCCACATCGCAGCCATCGACGAATGGCTCTGACCGACTTCGATACAGGCCCTAGGTCCCGGCTGCCCGATCCAGTGGTGCCAGTCGTCGTTATCCCCGCACGCGCGGGGCTGGTCCCACGATGCCGCGCTCGACGAACACCTCGTTCCCGTCGTCCCCGCGTACGCGGGGCTGGTCCCTCGGCCAGCACCCGGCGGAGGTTCCGGATACTGTCGTCCCCACGTACGCGGGGCTGGTCCGATCGATTCGCTGAGGACCTCCGGCAGCACGATGTCGTCCCCGCGCACCTGGGGCTGGTCCGGTGAAGGGCCTCTCCCCGGCCGGGCAGCGGTAGTCGTCCCCGCGTACGCGGGGCTGGTCCCCACACCGGCAAGCCCGAGGCGATCCTCACGCAGTCGTCCCTGCGTTCGCGGGGCTGGTCCCGACACGACGGCGAGCCGGTCGTCGCGTTCCTTGTCGTCCCCGCGTACGCGGGGCTCCTCCCAGGACGTCGCCGGACTCCCCATCGAGAGGCGGGCTACGCCCGAGAAGGCCCGCCCGACCTCATCACCGCCGAGTCGTCCCGTCAGTAGCGAAGTGAACGAGAAACACTGTTTCCAATGATAGATTCGCAGGTCAGCAAGTGTTGTCCCCGCACGCGCGGGGCTGGTCCCTGCACGACCGGCCAATCGACCGCCTTGTAGTCGTTGTCCCCGCACGCGCAGGGCTGGTCCCACGAAGTAGATGCCCGCGTGCTGGATGGTGAGGTTGTCCCCGCACACGCGGGGCTGGTCCCATGCCGGTCACACCGCTCGGATGCCGCCGTTGTCGTCCCCACGCACGCGGAGCTGGTCCTTGGGTGGCCGACTTCCTCGGCCTGGACAAGCTGTCGTCCCCGCGCACGCGGGGCCGGTCCGGCGGAGAGCGACAATAGCTCTCCGCCGAGAGCACTATCTGAACTGCGTTCGCTGCCAGTTGGGGTTAAAAGTGAGGTAACCGTGCGGATGCGCAAGACTGTCCGGGTGTTACCTGACATGGACCGATGGCGGCAACTCATCAGTGAGTACGGGCAGCTACAGCAGCTAACCGGGCACACACCTCAGACACGTGGTCAGCGCTTCAACAACATGATCGCTGAACTCCTACAATGTTGGGGCATCCAGGCCACGGCCAATGTCCGAGCCGCCGGCGAGATCGACGTCGCGTTCGCCATCGACGGCGTCCGCTTCGTCGTCGAGGCCAAGTGGGAGAAGACCAAGGCGGACACCGGACGTATCGCCAAGCTGCAGAAACGCGTCCGGCAGCGCTTGTCCGGCACCTACGGTGTATTCCTCTCCATGTCGGGCTACAGCCCAGAAGCTCTCGACGATATAGCCGACGGCGACCGGCTCGAAGTGCTCCTCCTGAGCATCGAACACTGGGAAGCCATGCTCGGCGGACTGGTGCCGCCACAGGAGCTGTTCAACCTGGTTCGCGATCGGGCCTCGTTCTACGGTGAGCCGTACACCCCCCTCGCCCAGTTGTTCGCGCCCGCCGAGATACCCGACATCCGCCTCGGGCCGCCGAGCGAGATGACTGACGGCCCCCTGCTTGAAGCTGTCGACGGTTTGGACGCGCAGGTCGTTCTGTCCGGCATCGAATCCGGTCAACTCGGGATCGCCTGTCACGGCCAGAACAGTCTGCTGGTGACGACTGAACACGGAATTCTCGACGTCGACTTCGAGGCGCACACGGTGACAATGGCTGCGCCGGTGCCTGACTGCCAGCGGAACGTGCTAGCCAACGAGGACGGATCGATCGTGTTCCTCCGTCGATCCGGCGTGGGGCTATTTCGCGATGGCCAGATCACGACAGTCGGTGGCGGTCTTTCTGGGAACAGCTGCCTATGCCGGCATCCAGATGGCAGTCTTTGGGTCTTCGACAACGGCGGACTGCTCGACCACAGCGCCTCCGTAACCAGACTGGACGACAAGCTCGGCCTTCAAAAACGGCATAAAATTAATTACTCGCCCGCCAATGCATTCACCTCGGCGTGACTTTCTGCCGATTCGTTACTGACGGTCGGAAACGCAGGCTATCTTGTCTCGTCGCCAGCGACCGATCAGGAGTCACGGCATACCGACGCTCAGTCGAATCCCATGGGATTAATCGCGCTCGATGAAACCTCCTTCCTGACCGTTGGCGACAGCGTTTCCCTTCGCTGGACGGAGATTGAAACATGGACCAGCCGAGAGTTAGCGCGAGTCGCGCTAGCACCCTCGGTCACTGAGCTTGCGTTGGCAGTCAACGGTGACCTGTACCTAGCCGCCTACCAGGCTACAACTAACCGCGGCCGCATGTCGTTTGCTGTCATTCGCGCGCGGTTGCCACCCGAACTGGGCGATCTCAGACTACACGCGGATCTCGCGATGGCGACCGTTGCCACACGGTCCATAACTGACACCAGCAAGGAAGAAAGGGACGATCGTCCGACTCCCGGTCTATTGCCGGTCTATTGCCGGAGAAACGTCAGAAGAGTAGCGACCCAGGCGCAGTTCCCGGCACGACCGCATCAAATTCATCAGGCGATACAGTCCCTTCCGACAGAACGACGCCAGAACGAAGAGGGACCGCACTCCGGACTGGCGACGATGTCGGTACTACATTCTCAGTTCCGCCGGCGCCGTTGCCGAAGCGGATGAATGCAGTGCTGCGACTGTTCGACGCGCCGGTCTATCGGGACTGGTTGTTCTGGTTCATGCTGGCATGGGCCGCGCTCGACTTCGTGTCGGTACTGACACTCGGTCCGCCGAGCGGCCTGCCCAGATGGCTGACCGCGCTGATCGGCGCCGCATTCTTTGCCCTGGTGTGCGGACTTGTCCCAGCGTGGATTCGCCTCAGACTTCGACGTCGGCGCCACGGTCACGGCCGGATGGCCACGAAAGAGAGGTAGGAGGACTCGCAGAAGCCTAACTGAGCGAGCGTGCGACTACCGGCACTCCGTCGGTCGTGGCAGTTGAGGGCAGCACCGAAAGCAGCGTGTGCGACGTCGTGAGCAAGCTCCATGGGCTGGCTGATCGAGGGGGGCCTCGGTCGGAGCACGAGTCGAGCTGACGCCGACAACAGCGCCACACCTACTTCATTGAGGTGTCGTCCCCTCGCAAGCGGGGCTGGTCCCGTAGGTCCCAGGACACGACTCCTGGCGCCCCCGTCGTCCCCTCGCAAGCGGAGCTGATCCCGTCTCCGGGTTGAACCCGAGCCGCCAGTCCACGTCGTCTCCGCGCACTCGGGGCTGATCCCTGGATCTGGAGTCGGTCGTACTCGCCGAGGTTGTCGTCCCTGCGCACGCGGGGCTGGTCCCCAGGAGTCCGGCGACAACCCGACTGTGGTGAAGTTGTCCTCGCGTAGGCGGGGCTGGTCCCATCTTCACGATGTTCTCCCACACGATCGTGCCGTCACCCCGCGCAGGGGGGCTGGTCCCGCAGAAAGCCTCCTCCCAGGCCCGTCAGGACGTCGTCCCCGCGCAAACAGGACTGGTCCGAGCTCCGTCCGGGTTATGAACGAGTTCGGCTTGGTATCCCCGCGCGGGTGGGGCTGGCCCTGCGCTCTCGCGTCGCAGACCGTCATCTCCGATCGCCCCCACCTCGCAGGCGGAGCTGGTCCCCATGTTGTTCCCGTCATATGTCAGAGCGTTCGCGATGGGGCGAGGCTGATCAGGCCGCAGCCGTAGGCTTTGGCGCGTCCGATGCCGTTGCTGAAGGCGTCAGTGAAGGCGGCTGGGTCGGTAACGATGAGGTGTCCGTCGAACCGGACCGGTTCGATAGTGATCTTGCTCGGTTCGCTTTTGCGTCCGGTGATGGTGGCGGTGGGGGTAATGGCGATGTCAGGTCCGGCTGCGGTGGCGGGGATGACGAAGCCGTGGGTTTGGCCTTGGCGGATCAGCCAGTCGATCTGGTCGGCCGGTTGCCGGAGGGGAATCCGTTGACGGGTCTTGTTGTCGCACCTGGTGGGATTGGCGACGAAGCGGAAGGCGAGTTTCCGGCCGGCGGTGATGGCGTCGAGAACTGGTTGCAGGGGACGGATTTCGGCGGGTGCGTTCAGGTGTCCGTCGGGGAGCTTGTCCCAGTCGGGGCGGGTGTGGCTTTGGACGTATTGGACGTAGCTGCCGCGGTTGCTGTCCAGGCGCCAGAGCACGCCGTGGGCTTGCCGTTTCGGGGTGTCGGCGGGGACGTCGGGATAGACCGACATCAGGGTCCGGTGCATGTCATGGACGTTCGCGTAGTCGCGGCGGAAGGTGCGCGAGTGTACATTTATGGTGAGTTTGCTCAGGAACACGTGGTGTCTCCGGCGGGGATCATGTTGTCGGTCAGCGGGACTTCGCCGACGAGTACCGTGCGAGTGGCGAAGCTACGGGCACCGTGGGCGAAGGAGCGGGGGACGTCGTGACGTGGTTCGGCACCCACGGTGCCGGTCGGACAGTCGACAACGGTGCGTAAGGCGATCTGCTGCTGACCTGGGATCATCGCACCGGCTCGGTCGGGGTGTTCGAGCCAGCGGTGCTCACGCAGGATCTGCTCAAGGTTGCCAGCATGGAGACCGTCGTCAAACAGCGGACGGGCGGACACGAAGGCGCGGCGGCCAAAGAACAGCGGCCAGCGAGGGTTCGTTACCGCATCGGCCAGCTCGCTGAGCAGGGTTTCTGGTCCTTCGATCGCGACGAGGAACAGGGCGTCGGCGAGGTAGTAGCGTTCGCTGACGACCGTGCGGTGCCCGGATCCGGTTGTGGTGGGCACGTTCTGCGTGGTGTGGTAGTCCCGTTCGAGCAGGCCTTCCCGGTCGACGCGGACACCGAGACGCAGCGCGGCCAGCGTGGCGATGCCGGCTTCGTCGTCGCGTTCGACTCCGGTGGCAGCGGCCAGCAGTCCGACGACTCCGGATTTGGTGGGTTCTCGGGCGGTGTCACGCAAGATGCCGCGGGAGCGTAGACCCCAGGACTGCATGGGGGCGTCGAAGCACAGCGCCAGCGTGTGGGTCATGCCGGTGTCGTCCCGGCGGCGAGGATGCGGGAGGTGAACTCGTCGATGCTGGCGGCGGTGTCGGTGCCGTCCATGTCGGGCAGTTGCCCGGTGACCGATGCCGCGACGGCGGCTCGGATGCTGCTGGAGCCGTAGAACGCGCGTAGCTGCTGGAAGTGCTGGGTGAGGCTGGCGGTGGAGGCGGCCATGATGTCTTCGCCGGTGACCGGCTTGAGGAAGGCATTGGCCAGGTTCCAGGCTCCGCCGTCACGGACGACGCCGAGGAGGGTGTCGGGCATGGTCCGCGCGGCCATCGAGTTCTGCTTCCCGCTCGGCACGGCGTGGATGAACGCGCCGAGCCAGGCCCGGGCAGCGCGGGCGACCAACTCGTCATCACCGGCGAGGTTCTGGCGGAGCCGGTCGAGGTCGAGGTTGGCGTAGCGGTAGTAGCAGGCGGCGTTGAAGTCGACGGTGCCGATCATGTCCGCGCCCGATTCCGCTTCGGGTTTGAGGTCGTCGACGGCGGTGTAGTAGTCGAACTCGGTGGCGACGGCGTGGGTGGACAGAGCGTGGGCGACCTGGGAGGCGGCGTCGACGTTGAAGTCCTTGTTGTCGGCGATCATGCGGCCGAACAGGGCGACGTCGGCGACACGGGTGGCGTCGAGCATCCGCTTGGCCTCGGCGAGGTCATTCTTGTCCGGTTTGGCCTTAGCCGGCTTCTTCTTCCCGTCCTTGGCCGCGGCGACAGCGGCGAGCGTGTCCCACCGGTCGTCGCAGTAGCCGGCGAGGTGTTCGATCGCGGTGGTGCCGACGAACAGCAGGTATTCGGTGAGGCCCTTGTCCTGGTCGACGCCGAAGCCGAGCTGTTCCAGTCCGGCGGTGACCACTCCGGCTGCCTCTTGCTCGTCGCGGCCGCGTTTGGTCAGCAGCGCTGCCGCCTCGTTGCGCAGCCGTTTGGTGCGGATGCCGGTTTCGGTGTCGGTCAGGCCGTGGTCGGTGAACAGCTGGCGGGCGGAGCGTTTGAGGCACTGGCTGGAGATCCGGCCGCGGGTGCTGCCGCCGAACGTGGCGGTCTTGGGCTGGCCGACGTCGTCACGGTTGAGGTTGCTGACCGGGAAGGACTGCAGCAGGTGAAGTTCGATGATCACGCGGGGTTCTCCACAGTGGTCGGGGCGGGTGCCGGTTCGCCGTTGTCGGTCGTGGTGGTTTTGCGTTTGCGGTGGAAGTCGCGGGCCCAGCGCAGCCGGATCCGGTGCGCGGTGTCCTCGCTGTACTTGTCGCCCATCAGGACGACAAGGTCGTCGAGCAGGGCGGCGTAGTTGACCGGGATCCCCTCGGCCGCCAGCAAGCGGACGATCTGGCGCAGATGGTGCGGCAGCCCGGCCCGGTCCCGGCCGAGCAGCTGCTCGAACCGGCGGGTGGCCGAGTCGCCGCGCTTGTCCTGCAGCGCCTGCATCGCGGTGCCGATCGAACGGTCCCCGCGGCGACTGGCCTTTGGGTGCAGCGCGAACAACCCCGCGACGAGTATCCAGGCGTCCTGCTCGGACTCGGGCGGGTCATGGCGGAACACGACCTCGTACGCGGCAGGTTCCGGGCGCGCGGTGACCAGGCTGCGACGCAGCCGCGCCAGCACCTGGCGAGCCTCCGAGCGCCGTTTCGGGATGCTGGACTCGAGGCCGGCGTTCAACGCGTACAGGGCGGAGATGAACCCATCCCGCCGCTGGGCAACCGGTGTGCTCACTCGTGGCCGTCCTTCGTGAGGTACTTCGCGATCTGGGCGTCGTACGTGCGGGCGATCGTGCGCAGCCGATCCAGGACGGCGCCCAAGTGCTTGCCGATCATGTTCAGGCTGCGTCCATCCGCGGCAATCCCGGCAGCCCAGCTGTCCGCGGCCTGCTCCGCCACGGAGGTGACCGCGCGTCGCCAGCCGGCCATGGCGCGCTGTTCGGACTGCCCGGCCAAGCGCGCGTCGTTCAGAGCGCGCAAGAACGCGGCGAACGGTGTCGGCAGCGCGGGCCAGTAGGCCAGATCCAACGTGACGTCGGGCTCGGCGCGCATGTCCTTGTGGTACTCCCGCTGCATCGCGCGCAGTGCCGCGCCGGCCTCCTCGGCCAGCTCAATCGCGCACCCGACCAACCCGGTCAACGCGTCGTCCCCGGCCCGGATCAAGGCGACCGGCGCCGGGACTTCCTCTTCGAGGTATGCCTCGACGACGCTCGCGTTCGCATCGAGCCGCTGGCCGAACACCCTCAGCGTGTACACGGTGTCGGCCGGGATGGAGCCGTGTTCGGCGAGTGTGGCGAGCTGTTTGAGCGCCTGCGGACGCAGGCGGGTGCGTTCTTCGGACCAGGGGTCGACCAGCAGCAGCTCGACGCTGTGCCGCCACACGCCGCGGACTGGTTGCAGCCGGATCGGCAGCATCGGCGCGTCCGGTTTCGGTTTGCCGCTCGGTGTGCGCGGAGTTCGGTAGGCGGCCATGCGTTCGATCTCCGGACGCTCACCGACCAGGCGCGTACCGGGCGTAAGAACTGCGTTCGCCACCACGGTTGCGCCGTTGGTGTGCTCTGGGAGTAAGCAGATGCGCCGTGACGGCCAGGTGAGGACGTCGGTCCATCCCCGCGATCGGCGTTTGTCCGGTTCCGGTGACGGTGTCGGTGCCTCCCATGCCGGTGCGTCGTCGGAGGCCTGGGCGTCGTAGCGCACGGCGTTCAGCAGCAGCGTTTCCTTGAGGTTGGCGCCTTCGACGAGGACGACGCCGAAGTAGTTGCAGGGGGCCCGCTCGGATGATTTGTCGGTCTTGTACGGGGTCTTCATCCCACCGGGGTCGAAGGCCTGTGCTGTCACCAGCCATCGCGCCGCAGCCGCCGGGGTCAGCTCGACCCGGTCTTGCGCGGTGGTGTGGTCAAACAGCGTCACCCGGTTCCCGACGGCCCGGTGCGGGATCAGCTTCGCGACCGTCGACTTCTTGCCCTCCGGCAGTCCCGGGCATTGCAGGAAGGGACGTTGCAGATCGAAGAGGTCGAAGGACAGGCCCGGCCGGTCGAGGTAGGCGGCCAGCAGCGCCGGGGCGAACGTCTCGGTCGTCCACAACTTCTCCCACTCCGGCAAGCGAGCCGGCCCGTAGGCGCGGTGCAAGATGGCCAGCGCCAGCCGATACAGCGCCGCGGTCATCGGCGGGGTCTCCCCCACGATTCGACGGATCCGGTGTGCTGACGAGAACAGCTCCCGCAGTCCCACCAGTGTCTCGGCACCGTCGGGTTCGTCGAGGTAGACCACTGGAATCCACGATTCGGTGGTGAGGTCGAAGGTCGCGCTCATGTCTCCTCGCTCGCGTAGACCCCGAACTTGTCGTGATATCGCAGCTCGTACCCTGCGACGCGGCACTGGCCGTCGGTGAACACCAGCGCACGATGCCGGTTCAGCCACGGATCCGCAGCGAAGTCCGCGGGCACCTCGGAATCCAGCAACGCCCGCACCACCGCCGCGGGCACGTTGATCGGCGCCGCCAGCACCGTCGCCGACTCCAGCAGGCCATCCGAGTCCGGATACACCGGCTTCAGCTCGCCGTCCTGGTCGCGGCGGTAGAGAACCACCCGCACCGACAGCTCGGCCAGTTCGTCGTCGCCTCCGGTCAACGCTTCCTCCCCGTGGACTTCCGAGTTCGCAACGCACGAGGCCGTTCGGTCAGCTCGGATAGCACCTCGACCATGTGCGGCTGCGGAAGATACGACTCCGCCGCAGCCTCACGATCGTTGTGCTGCGCGACCGCCAAACGGTCACTTTCCCGGCGCCACGCTGCTTCCCAACCCCGCGGGCACGCGACCTGATCGCCGTACACCTCGTCCACCAGCTGCGCCATCGTCGTCCACGACTCGATCCGATCGAGGTCCTTGAGCGCGGCCCAGGTGCGCATCAGCACAATCGGCGCGTACACCGTCCGCAGATACGCCGGGAACTGCGGCCCAGCCGGAGTGTCGACGACCCCGGTAATCGCCACCGTCAGCCGGCCTCGCGCCGCGTCGCGGCGGTGGCGGTGCACCCGGCCTGCGCGCTGGAACACCAGGTCGATCGGTGCCAGGTCGGTGATCAGCGCGTCGAAATCGAGGTCGAGGCTCTGCTCGATCGCCTGCGTCCCGACCACGATTGCCCGACGCGGCCTCATACCGTTTTCACCGAAGAAGCCTTGCAGCTCCTGCTCGACGCGTCGCCGCGCGCCGGTGGGCAAGGTGCCGTTGATTGCCAGCAACACCGGCCGATCTTCCTCGGGAAGCTCCTTGATGCGGCGTTCCAGCTCGGCGTAGGTCTCGGTGGCGCGCCGGACCAAGTTGTGCACGACCGCCACACAGCGACCCTGCGCAGCCACCAGCAACCAGTCGACCACCCGCTCGTCGGGAACGTGCTCGAGGTGGACGACGCGGTCCCGGTTGAGTTCCGAGATCTCCACCGGATGGTCAACGACCTCGGCAGTGTCGGCCACGGTGACACGCGGGTACGGCTTCGACGCCGGCGGGACGTTGATCTCCTGCGGGTAGCAGCCGCGGTACCCCGCCTGCCACGCGGCGATCAGCTCGGCTCGGCGGCTCGAGGGCAACGTCGCCGACAACAGCACCACCGGCGCGCCCAGCGCGCCCAGCCACATCAGCAGCCGCTGCAGCAGAGTGGACATGTAGGTGTCGTAGGCGTGGACCTCGTCGAACACGACCACCTTGTTCGCCAATCCCGCCAGCCGGACGAACACGTGACCCGACCGGAACGCCCCCTTCAACGCCTGATCGATCGTCCCGCACCCGAGCACGGACAACAGGCTCCGCTTGCGCGTGAACCACGCCTGCGCCTCGGCATCCAGCGTGCCCGGTTCGTCCACACCGACCTCGGCGGGCTCCGCCAGGACCTCCCGGGCCGCAGAATGCACCAAGCTCACCGTGGTCGGATCGCCGAGACGCGTCAGCATCGCCTGCATCACGGCGAACATCTGGTTGCTGGTCGCCTGTGTTGGCATCCCAAGATACGACCCCGCCAGACCGAACTGAGAAACCATCGTCGCAGTGGCCTGCAGCGCGGCCTTCGTCTTTCCCTCCCCGGTTGGCGCCTCCACCACCACCAGCGCCGACCCCTCGAGGTCGGCGGTCACCCGCTCGATCACTTCCTGCACGGAGCGAGGCGACTGGCCGAAAAGCTCATCAAAACGAGCACCGCCAGGAGGCGACCAGGAGCTCATCTTCAGCCGATCAACCGCCGCTTCAGCCTGCACAGCCGCATCCTTGGCGTAAGCCGCGAGATCGACCTCGTCTTCGGCGAAGGCGAAGTTGCTCGTATCCGAGGCGATCCAGTCGCTCACCGTCGTCAGCGCAGCCAACCCCACCGCCGCCGGGACCGACAGGTCCACCTGCGCCCAGTCCAGGGTCCGTGGGTCCGGCAAGCCTCTGAGCCGAGCCAACTCGGCGACCAAGGTCGTCCGCTGCTCCGCCCACACCCGCTCACCATGGGCGTTGATCTCACGCCGGGCCTGCGCAACGACCTCACCGGCCGGGAAATGACCATGATGCCCACCCAGAGCCGCGGCGATCATGACCGCCGTGCGCCTCGACGCACCCCATGAGACCAAGAGCTCCTGCAAGTGCAACGCGGTGAGCAATCCATGCGGCGTATCGACCCGGCGCGGCACCCCATGCAGCTTCGCCACGAGTTCCAGATCCCGTACCGCCCATGACCCCAGCCGCGCCGACGACAACGGAAAATTCAACGCCTGAAAAGTCGGCGAATACTTCCCAAGATCATGAACAGCGCACAAGAACGCCGTCCAGCCCCACGCATCACCCAGCACTCCGAACGCTGCTGCCAGCTCGGACCGCACCCTCCCCCGCAACAACAGCGGCGCCAACCGCTCCGCCACCGCCGCCGTATCCAGCATGTGACAGATCAGCGGATGACAACCAGCTCGCTTCGCCGACTTTCCCCACGGCAGCCAAACATCAGACACCGCCCCACGCACCCCTAACCATGCGTCCCCCTCGACTGCGCTTCCCCACCAATCGCCAGCTAAGGCTCGGCACTCTATACCTGCCTCAAACATCCCTCCGCCACCTCCCCCCTTGAAATCGCCAGCTACAACAAGGTCTGGACAATTCACGTCCGTTGTCAAACCGGGCCAGGATGCAGCTCCACCGCTGAGACCCTCGACGTATCCCGCCATAACAAATTGCCATACTGTGATGACGGCCCGCGCGGAGCTGGTCCGGTCAGTACGCGGCGACGCCGGCTACCAGCCAGTCGCCGCCACGTACGCGGATCGGTCATTCACTTCCGAGTGCCTCGGACGGTCGGGGTCGTCGTCCCCCACCGGCGGGCTGGCCCCAGCGACGGCCGCGGCCAGTCCTGGTTCACCCTGTGATCCCTGCGCACGCCGCGGTGGTCACGGCGCGCCGAGGATTCCGGTCGCTGGTGGGCGTCATCCCCGCGCACGGGCTGGTCTCAATGTTCGTGCGCTGAGGCTGGCCGACCATGCGTCGTCTCCGGCGCACGCGGGGCCGGTCCGTCGTCGAGCAGCGTGCGAAGATCGGCGTTGACCTTGATTGTCCCCGCAGACGCCGAGCTGTCCCGACGCCTGGAACACACGTCCATGCCCTGCGTCTTGTCGTCCCCGCGCACGCGGGGCTAGTCCTCTCTGAGGTTCACCCCGAACGGTGGACAGGGGCTTACACAGTTCAAGCAACCACTGGCAGCGACTTCTCGTAGTCGTTGGGGCTGAGCATCCCGATCGAGGAGTGGCGCCGCCTACTGTTGTAGAAATTCAGCCATTTGTCAATCGCGGCAACGAGTTCCGTTTTCGTCGCGTAGACGTGCCGGTAGTATTCCTCATGTTTGAACGTCGACCAGAATGATTCCGCCGGGCTGTTGTCCCAGCAGATCCCGGTCTCGCCCATCGACCGGCGCAGCCCGTGACCGAAGCATGCCTGCGCCGTCACGTTCGCCGTGAACTCGCCGCCGCGGTCCGAATGCAGAATCGTGCCGCGGCACCCGCTGCCCCGGCCGGCCACCGCGTCGTCGATGGCGGCAGTGACCATCTCGGCGCTGATGTGGTCAGAAACGCTGTAGCCCAGCACTTTCCGGGAATGACCGTCCCGAATCGCACACAGGAACATGTCGCCCTCACCACACGTCAGATACGTGATGTCGGTCAGCCAGACCGCGTCGGTCCGGCCCCGGTCGAAGTGCCGGCCGACCAGGTCCGGCGGGAACGACGCGGCCGGATCGACCACCGTCGTGCGCACCTTGAACGTGCGCGGACTGATGCCCTCCAGCCCCACCCCGGCCATGATCTTGGCAACCGTCTTCGCCGTGACCACCTCGCCCTGGTCGCGAAGTTCCGCGGTGATACGCGGCGACCCGTAAGTGCCACCGGAGTCCTGGTGCGCCTGGGTGATCTTCACCTCCAGGTCGGCCCGGCGTTGCCGGCGCGGCGCCAGGACCGTTGCGGCGGCGCGTGTGGCGTGTGCGTAGTAGCCGGACCTCGACACATTCAGCAGTCGCGCCATGCGCCGGACCGAGAACCGACGTTCGTTCCGAAGTGGGACCCTGCCGGCAGTGTCGGCGGACTCGTCGGGGCCGGCGTACTTGGCCATCAGAGCGAACCGGGCCGGTTCTTCTGCATCGCGGCAAAGTACGCCGAGGCTTTTACCAGGAACGCGTTGTCCTTCTCCAGCTCGGCCACCTGCCCGCGCAGCCGCAGCAGCTCGGCCCGCTCGGCCGCCTCCAGAGGGTTCTCGCCGTGCACCTCGGCCGCGGTCACCCGGCGCCGCTCGTCCTTGACCCAGACACTCAGCATGCCCGCGTCGAGACCCAGCTCGCGGGCGACCTCCGCGATCGTCCGGCCGGAATCGATCACGCGGTGAGCAGCCTCGACCTTGTACTCCGCCGGGTACGACCGGCGCTTGCGAGGAGGCATGAGGACATCCTTCCAGCAGAACCCCTGGTCCTGCTAACTCGGTGTCCACTACCCGGGGTGAACCTCAGTTCGCCAACGCGACTGTCGCCTGTGGCGGAGCGGAAGGCAGCGTGTCGAGAAGCCATCCAGCGTCCTCGCTGGTGAGCAGCCCCAGGGTCAACACCGCGTACCAGGTTTTCTCCCCGACGGCTGCTGCGTCGACGGCTAGAGCCCGGCGGCGTTCGGGAGCACCATCAGCCCAAGGAATCTGCTTGATTCGAGCCGATGGGCGATGCCACAGACCGGACCGGACCAAGCCGACAAGCAACCGGGCCAGCCCCGCGCGAACGGCTTCGTCGCCAACCTGCGGCTAGGCCCGCTTGATCACGCCGGCATAGAGGTCTTCGAATTGGTCGTCATCGCGGACATCGCTTCGCCAAGCGTGGTCGGCCAGCCAGGCGACAAAGTCGGCGAGGTCGTTCTCGGGAACGCGGCTGGGCAACTCTCGCAACGACTGGAGATAGCCGCCGAACAGCATCGATCGGTGCGGTCTAAGCGCCTGGGTGAGCTCGACGGTGCTTAACAGCCGAGGATAAAGAGCATCGATCACCGCGGCACGGACTTCGTTGTCCGCGTCAGGGTCGGTGTCGGTCGGCTCGGCGAGCAGTTGGCGCAGCGACAGCTGGAGATCGTCCTCGCCGAGGTCGGCGACGGCGGCGACTGCAGCTCGGCGTACGTAGCCGAACCACGCCGGCTCCAAAGCGGCACGGGCCAGCGCGGGCGCGAGGGTACGGCAGCCGCCCGCCGCGGCCAGCCGGGCGATCCACCAGAGCTGCGGCGCGTTCGCCGGACCCCTCCCGAGGTATTCGGCCAGCTGCTCGGTCAGCCCCGCGTGGAGCAGTCCTGTCCGGTCGAGTCGCCAATCAGGCTCCGCGTCGTCCCGGGCTGCAGCTTCGAGCAAGCCCTTCACGAGAGCCGCTCGTGCTTCGTCAGATGGCAGCTCGACCACCGCAGCGGCAGAAGCGAACATCGCGGCGTTGTCGATGAACAACTGCGCGACCAGATCTGGGGCTAGAGCGGCCAACCAGGATGCGACGCCGATCCGCGGGGTTGGCAACAAGCCGTTGACGTGCACGCCGAGCAGAACCGGAATCTGCCCAGCGCGGATTCCTCGCTGGACCAGGTAGGCGGCAGCAAGATACTCGAGGTAACGCTGGTGCCGGAACATCACCGAACCCGCCGGCCCGGAATCGAACAACGCTGTGTCGAGCACTGCTCCGTAGTCGAGGGGCTCGATGGTCCGTGCAGGCTGATCCGGCTCCGCGTCCGACGGGAGATCACTGACCGGAAGCGTTGCGCGATCCCCCACCGCCCTGACGGTGAGTGCCTGGTTGCCGGCGAACATCGTAAAGGCGCCGAGCCGCTGGGCCACCCGCATTGACCGGTCCAGCGGCAGCCGTGGCTGCCGACGCTCGTCGGTCTCGCGAAGCAGGTACTCGATCTCGAATTTCATCGCGTCCGCCGCGCTGCGTGGTAGCACACCCTGTGCATTCCAGTACCGCGCGACAGCGACGAGTTGGCCCACGCACCCGGATAGTCTGCCGAGCTTGGCCCCGACCAGTGCCTTCATGAACGCCGCGGAGTCGACCTCCGACACACCGATCGCGTGCTCAACCGCCTTGGATGCAGTGTCGCGGTCAAGCGGGGCCAGCTTCCACACGGTGAACGCAGTCATCTGCTGAAACAGCGCCCGGCCGAGTACCGCGTCCCACGCGGCCGCGCGGCACGCGAGCCGCGAGCGCATCCCGCGACGTGCGGGCGCAGTCAAGTACCGCTCAAGCCACGGGAACAGGCGCGCTTCGACGGACGCCGCCTGATCGAGGCCGTCCAGGTAAACCGCGGATTCGTGGAAGCACGCGTCGTCCAGTTCCCGCTCAAGCCCGTCGATCGTGAGCGCGGAGGTGTCGATCCGCCGGGCGTCCGGCTCTGCATTGGCGAGTTCGGTGAAAGTAACGGTCTTGCCGGCGCCACCAGCAGCAAGCAACGCAAAACTCACCACCTCGGTCGGCAGTTCGGCCACCGGGACCGGCGACACCGCCTCTCCCGATCGCCACCGGGCGTCCGACGTCGCCAGGAGGAAGCCGTCGTCATCGAGGAGAACCGGCTTCTCCACCGGCACAGCAAACCGGCTCAGACCGTTGAAAACCATGACATCGCCGTCCGACACAGATCATCACTATAGGTAGACTTGTGTGACGTCCTGTGTCCGGGTTCTGCGAGGCACGGCATCGTCACTCCATCAACCTCCCGCCCACACTCCGCGAACGGCTGGCCAGCACCCCATGACAGCGTTTCCGGTACCCACAGGTGAGCACCGGATTTCGTGGCGTCCTGTTTTTGTCCACTAAGCCAGATTCGTCCACTCGGTGGGCTCTTTCACCGAGAGTGAAGCCTGGTCGATCGACACGCGCAGTTGACGTCGCGCCCAACCTCGTCGGCTGCACCGTTACGCGCAGCAGAAGATCCTTCCGAATCCGACGCGAGCTTGTAACCTTATGACGAAGTTCCTCTAAAACCGAAATTCGCAGGAGGGAAGTTGCAACACGGGGTCGCGAGATGGCGATATAGGACCACGCAAGCAGACGGGAGTCAACACAGCTGAGGAGCTCGAGATGGAGGAAATGCCGGCGTGGAAGGTGAAACTGGTCCGCGTCGTGGTCTGGGTGCTCTTCGGAGTCATCTTCGGCCTCCTGCCGGTGATCATCGCAGCGTTCAGGGACTCGGTATCACCCGAAGGGCTCAACCTCGACAAGATGCTGGGAAGTGGTGAACTTCTGATCGTCGGAGCGGTCATCGCCGCAGGCGCAACGGGAGAACTCTTTGCCTCCAGCCGAGGGAGGTCCACCGACGGGATAGTAGCCAACCTAATGTGGATATTTGCCGGGTTTGCCGTCATTGCCGCCTTCGCAGCTGACACGATTTTGTATCTCATCGCTGTCGGACCATCACACTCAGCTATGACCAGCTTGTCTTTGATCTTCTTTTCGGCGACAGTAGTGGGGACCACCATCGCGGTAGGAACGGCGGCATGAGATGAACGCATTGGTGTGGGCCGTCGTGGCCATGTCAGTCAGCGCCCTGACCGCTCTGGGGTCTCTAGCCATGGCGGTCGTGGCTAGGTTGCGTCCTCGTAAGCAGCCAACGCGTGTCCAAATTCGGACACCGAGCACCCAGGTCGCAGTCGAGCTCGACCCCGGCGCGTCTGACCAACAGGCGAAGGAGGTATTCGTCCAGGCGCTCGGACAGACACGTCAAGGCATCACAGCGTCTTCGCCGAGGGCTTCCAACTGCTGAACTCGTGAGCAGTGCACATCAGCTCAATCTCACCCACATGAGTGAGTTTCGCCTGACGAGAGAAGCGGTGACCGTCCCCGCGCTCCTGCTGGTGCTCGCGGCGAACGGGCCCGAACCTTCGCGCGCGCACCCACAGCTGAGTTCTCACCGACCGCGCCGTCACCTCATCCGTCGCCGCGCGTTGCAGCGGGATCAGGCGGACGACGTTGTCGTGCGCCTCAAGCTGCAAGCCACATTGCTGCCGCCACCCGCCTACGAGGCTTTGCTGACTACTACCGCGGACCAGCAAAACCGGGACCAGCACTGGGCCGTGACCGACTGGGATGGCAAAAGCATGGCCCACGCCGCCCACCACAACGACAGCACGACCAAGGGCTTCTCCTAGAGTCGTGCCGGCGCAGAGACCATCTTGGCGGGGCTATGATCGTCGCCAGCGCGATGGTCGTGCGGCGCTCATACCGGCCCAGCACCGGTTCGGCCAGGCGTGTCCGCCACGAACGCATTGACCGCCCGAGAACAGCTGGCTCGTTCAGTAGTCATTAGGGCCCCGTCCGCGCCGTCTTCGTCGCTGGCCTTCGGAGGCCCGGGAGCAGATGTCGGAGGCAGGCCGCGCCGCGCGCATCACCGGCGTGGTGTGTCGCCGGCCGCGAAGACGACAGTTCCACGGCATAGTCGCGGGCAAGGCGAGCAGCCGCGTCCTGACCGACGAGCGGTGCACCGCTGCGGGCCCGCACTGACCACCTGGGAGATCATCCATAGGGCGCGCTGATGTACGGGATCGGGCTGACTTCGGTTTCCAGCATGCTGGACGAATCGTGTCGGCCAAGGTGCCGGAGCGGGACACGGCCCGGCTCCGGGGGCGATCAACACCGTCCTGCAGATCGGCGTCGCGGCCGGTTTCGCGATCTCCGGAACCCTGCTGGTCCCGTCAGTCGCGGCCGGCGAGCCTTCACCTCGGCGACCACCACGACCCTAGCGGCGGAGGCGGCCATTTTCGTCGCCGCGGCGGTCGCGCCCCTGGTGATTCCGCCGGGGAATGCACGTCGAGCAGTGAGCCAATCCCAGCCGGTCGCGATCACGCGCCGCCATCGCCGTGTCGACGGCGAAACGCACTCAGCAGCACCGTTCCCCCGCCGACACCGCCGACAAGCGTCGGACCTAGCAACCCGATCGCCGCCAAGCCGATCGAAGCGACAACTACCAAGAGCAGAAGCATCCGCACGAACGACTCGCGGTCGTCGGCGAAGGCCAGCTCGACAAGCCGAGCCAGCTGCCTCCAGCCGGCCGAATCCACCGCTCGACCGCTCTGCGACCGGTCCACACGTGGTCTGTCCATTTCCGCTCCCAACACGACTCACCGAGGGCTTCCGCTACCGATGGAATCCACTATCTCAGCAGGTCAACGGCGGTTTTACCCTCGATGACATCTCGTTACGCTCATCTGAGGCGGCTCAGAAACGGTGTGATCCCAGGCCGAAACCAGGGTGTGCGAGCCTATCGGTCCCCGCTCGCGCGCATTGGTCATCGGTAACTCGGTTTATGATGAGTTACGTTGCGTGATGCCGCGAGAGGAGACGCCATGGGGCGCGCTTGGCACCAGCCGGACCTGCCTCCCGGCCCGGTCCGAGCGCTGAAGACCGCGTTGCACCGGCTGCATGCGAAAGCCGGGTATCCCAGCGTCATGCAGGTCGCCCGCTGGATCGCCCGGAATTGGACAGAGGAAGACAGCAGCCGCCCGTTCTCGACAACCACGTGCCACAAGGCGCTGATCACCGGCGAACTGCCGAACCGGAACGTGATGCTCTGGGTCGTCGATGCGTTCATCGGGCTAGGGCGCATTGGCGACGAGGAAGCAATCCTCGATTCGTTTGAGCGGCTGTGGCAGGACGCTCACGACGACCGGGTTCACCCGCGTTCGGCTACCGAAGGCCCTGGCGCCCCGACAATGCCGCGGTCCGATACCGGAACACAACCTGATCCGAACGGGGATCTCTCGCTAGCCAGTGGCCAGGAATTCCACCACCACCTCGGCGAATTCGTCGACCACCTGACTCAGTTCGCAGTCCTCCGCGAAGCCGACGGGCGACGTCTCACCATCCAGATCCTCAACGACGATCCGGATTGCAGCGTCGCTGTCGCCGAGCATTCGACAGCGCGGCCGCACCTCTTCGCCCTCGTCCTGGCCTGTCACAAGCAGCCGGGCGCTCTCATCCGGCTGTTGGACGTGATCGACATGCTGACGGGGTCGGACGGCCCGCCGACCGATCAAGCCAGGGCCATGCTCAAGGTGCCGGCCTCGCCAGGTCCGATATCGCAAGCCGACGACCTGGGCGAAGTCGTCGACGCACTGGAAAGAGTGCCCGAGCTCCGCGAACTCGCCGGGCGCAACCTCGCCATCGAGATGCTCACGGAATCTCTGGGGATCGACCTCGGCGTCGAAGAGATACCGATAACCCGACCGCACATCGCCGCCATCGCGAAAGCGTGCATCGTGCACCACCCCGGCACGTTGGTGAAGTTCGCCGAAGCCGTATCTGTCATATCGCCGAACTCCAAATCGACCGTTTTCGCCCTCGAGAAGGTCAAGAACTACACGCGCATGCGGGCCGGCGCCGGTTAGCACACCCGAGACTCCGGAAACCTCGGCCAGGAACGGCAAACCACGTCCGCCAACTCGTCGGAGACCTCCTCGGCGAGGTCCTGCGGGGTTCCGAAAGTCGGTTACTGGCGCTGACCAGGGACTTTACACGGCTCGTTCGTACTCGTTGATCAGACCTCCGAGCAGCCGCTGCCGCTTGATCCGCTGAAAGTTGAGGTCTGCCGCAGGATGGGTCGGCCGGGGTGGACGAAGCTCGCGGGAACGGTCGGGCCGGCGCCCGTTGTAGTGCCGGACGTACTCGGCGAGCACGGCCCGCAGATGCCTCTCGTTCAGAATCAACATACGGTCCGTGAGTTCGGTTCTGGTTGTCAGCACGAACCGCTCGGCATAGCAGTTCGCCTGAGGAGAACGTGGCGGAATCCTGATCGCCTCGATGCCCACATCAGCCAAGACGGCATCGAAGGAGGCCGCGAACTGACCGGCTCGGTCACGAATGAGGAATCTGAGCCCGTCGAGTCGATCCCCGAGATCCAGCACGAGGTTCCTGATCTGCTGGGTGGTCCATCTGCCGTCCGGATTCGTTGTCGTGCCCAGGACGTGGACATAGCGGCTGCCAACTTCCAGCACAAAGAACACGTAGATCCGCTTGAGAGTGAGCACGCAATCGACGTGGAAGAAGTCGCAGGCCAGCAT

Protein sequences of DBSCAN-SWA_3

>NC_017186|6405357:6460869|6423308_6423869_+|WP_013227603.1|DBSCAN-SWA
MEIAKLIVAALTPLSVALIGVVLTRSMRRLEHSNWLNQKLIEKRIEVLGEALPKLNDLYCYFSWIGTWASLSPVDVLQRKRDLDRLFHANRAFFTSSAFDVYGAFIDLLFETYAQPGKGARLRTEMTSHNGNRADVYPKKWEEGWSEMFSGVPRTSSLLTVKKCYEGLVMTFSAEVGIERSDAVGR
>NC_017186|6405357:6460869|6448036_6449617_-|WP_013227614.1|DBSCAN-SWA
MSATFDLTTESWIPVVYLDEPDGAETLVGLRELFSSAHRIRRIVGETPPMTAALYRLALAILHRAYGPARLPEWEKLWTTETFAPALLAAYLDRPGLSFDLFDLQRPFLQCPGLPEGKKSTVAKLIPHRAVGNRVTLFDHTTAQDRVELTPAAAARWLVTAQAFDPGGMKTPYKTDKSSERAPCNYFGVVLVEGANLKETLLLNAVRYDAQASDDAPAWEAPTPSPEPDKRRSRGWTDVLTWPSRRICLLPEHTNGATVVANAVLTPGTRLVGERPEIERMAAYRTPRTPSGKPKPDAPMLPIRLQPVRGVWRHSVELLLVDPWSEERTRLRPQALKQLATLAEHGSIPADTVYTLRVFGQRLDANASVVEAYLEEEVPAPVALIRAGDDALTGLVGCAIELAEEAGAALRAMQREYHKDMRAEPDVTLDLAYWPALPTPFAAFLRALNDARLAGQSEQRAMAGWRRAVTSVAEQAADSWAAGIAADGRSLNMIGKHLGAVLDRLRTIARTYDAQIAKYLTKDGHE
>NC_017186|6405357:6460869|6419104_6419881_-|WP_013227600.1|DBSCAN-SWA
MTADDELAKARHAYKVATERLNTAKARLKKAGRKALDELEQKFGKQVDVAAALHYSTSNVAKLRPNERDTPWEPRGLKFYKTVDKETGNRHDLGRLRTEFDQAKRAVSMAADAVHDAEATADIGSLDLESAAVTTATAVSIDDVQVFQKFRCVVLDVRVRNTGPSVANLTRVSLRILDRKSYLTAYAPSAGYDLLVDGDEGEVGVRHSLLPDEVDNFLVTLGFTEAESGYEFTAELGVRYNGDQVAVYRPLVFESCFD
>NC_017186|6405357:6460869|6445609_6446320_-|WP_013227611.1|DBSCAN-SWA
MTHTLALCFDAPMQSWGLRSRGILRDTAREPTKSGVVGLLAAATGVERDDEAGIATLAALRLGVRVDREGLLERDYHTTQNVPTTTGSGHRTVVSERYYLADALFLVAIEGPETLLSELADAVTNPRWPLFFGRRAFVSARPLFDDGLHAGNLEQILREHRWLEHPDRAGAMIPGQQQIALRTVVDCPTGTVGAEPRHDVPRSFAHGARSFATRTVLVGEVPLTDNMIPAGDTTCS
>NC_017186|6405357:6460869|6409172_6409784_-|WP_141748473.1|DBSCAN-SWA
MSTDDDPPDLRGREDRPKKPSFWRRWRSNRPFAPHERRMREDLIHELVNGRSRFSEREKVFGDVRGELIAKAGVYTACEARKGELTSTGGGLEQAHEQLVLAQEREGAGAVLLARRLEELRYQRRMADLPADLDDMPEHQGGTRRRPTRTRHSGRRRRTCTPTGTSTWPRWRPAANADTGACSPARLTASSSLSTSCSSSRST
>NC_017186|6405357:6460869|6407425_6407653_+|WP_013227592.1|DBSCAN-SWA
MTRTHRHDLSLGIQCFFTGLIAVGAAFASYRHGLHFALRFGADEATAWIWPLIIDGLLTIATVELWKAAGSKWQA
>NC_017186|6405357:6460869|6444968_6445619_-|WP_013227610.1|DBSCAN-SWA
MFLSKLTINVHSRTFRRDYANVHDMHRTLMSVYPDVPADTPKRQAHGVLWRLDSNRGSYVQYVQSHTRPDWDKLPDGHLNAPAEIRPLQPVLDAITAGRKLAFRFVANPTRCDNKTRQRIPLRQPADQIDWLIRQGQTHGFVIPATAAGPDIAITPTATITGRKSEPSKITIEPVRFDGHLIVTDPAAFTDAFSNGIGRAKAYGCGLISLAPSRTL
>NC_017186|6405357:6460869|6421783_6422272_+|WP_013227602.1|DBSCAN-SWA
MEAARDDLSHVSVPDLLGRYAAILQELQDRGVVRTRNAPLGDYAEYLAAQVYDGELAANSLKSYDLLAADGRRIQVKARTVAPDTRAGAVFSVFHSFEFDIAVLITFDSATYALRQAREVPAADLETAGRHSDHVNGRLIRITAGIRLGVDVTARFRAVASR
>NC_017186|6405357:6460869|6456895_6457315_+|WP_014467361.1|DBSCAN-SWA
MEEMPAWKVKLVRVVVWVLFGVIFGLLPVIIAAFRDSVSPEGLNLDKMLGSGELLIVGAVIAAGATGELFASSRGRSTDGIVANLMWIFAGFAVIAAFAADTILYLIAVGPSHSAMTSLSLIFFSATVVGTTIAVGTAA
>NC_017186|6405357:6460869|6460320_6460869_-|WP_013227619.1|transposase|DBSCAN-SWA
MLACDFFHVDCVLTLKRIYVFFVLEVGSRYVHVLGTTTNPDGRWTTQQIRNLVLDLGDRLDGLRFLIRDRAGQFAASFDAVLADVGIEAIRIPPRSPQANCYAERFVLTTRTELTDRMLILNERHLRAVLAEYVRHYNGRRPDRSRELRPPRPTHPAADLNFQRIKRQRLLGGLINEYERAV
>NC_017186|6405357:6460869|6426959_6427791_+|WP_085931694.1|transposase|DBSCAN-SWA
MDDVEKWCPEPLWLLAQPLLPEAPQRHQGGGRRRLDDRVVLAAILYVLQTGCAWSALPASFGVSAPTAHRRFTEWVETEVFARLHQAVLDLLGSAGAIDWSRASVDGMHVRAVKGGDLTGPSPVDRGKRGSKIHAISDRSGLPLAVGVSAANRNDHLELEAVVDAVVPVKGPAGRPRRRPRKLHADKGYDYPTCRKALRRRGIIARIARRGIESPKRLGRHRYVIERTLEWVSRFRRLARRYERKAAHFTAFTQLACAVICYRRAIKLDLLTHNNPK
>NC_017186|6405357:6460869|6407905_6408052_+|WP_155258934.1|DBSCAN-SWA
MWEFYEKERRQGRTPTGADLDRIAGTHNYGRRILRKWRAADLTTSTTT
>NC_017186|6405357:6460869|6443991_6444237_+|WP_014467360.1|DBSCAN-SWA
MLRLFDAPVYRDWLFWFMLAWAALDFVSVLTLGPPSGLPRWLTALIGAAFFALVCGLVPAWIRLRLRRRRHGHGRMATKER
>NC_017186|6405357:6460869|6458652_6458913_-|WP_141748525.1|DBSCAN-SWA
MDRPRVDRSQSGRAVDSAGWRQLARLVELAFADDRESFVRMLLLLVVVASIGLAAIGLLGPTLVGGVGGGTVLLSAFRRRHGDGGA
>NC_017186|6405357:6460869|6457614_6457962_+|WP_141748524.1|DBSCAN-SWA
MSEFRLTREAVTVPALLLVLAANGPEPSRAHPQLSSHRPRRHLIRRRALQRDQADDVVVRLKLQATLLPPPAYEALLTTTADQQNRDQHWAVTDWDGKSMAHAAHHNDSTTKGFS
>NC_017186|6405357:6460869|6428988_6430182_+|WP_080582935.1|DBSCAN-SWA
MMTKHPSNSDLPHEGDLNHGEERDRLTRPAVRPIPKWVVVTGVPLMMVIAISAAWLLLSTGATRDQLDALRTAGTLGVGFGGVVALWLAVRRQRSTEHDLLQKYQAHELAERVAAQNQAAADRAAAHAEHDARERRLTDLYLKAVEHLGSAHAPVRHGGLYALERVAQDNPSQRQTVVDVVCAYLRAPYTPPNTSRASRLGLKRPLQSSTRSRATNSARARETTTTSAHTRTISASLEEREVRMTAQRLLKRHLSLDIHDNSTGLFWDNIDLDLAGATLVSFDFRGCRVKHCTFLHSTFVGPARFDNAVFTGEASFARSAFTAEARFSGATFANETWFKGATFTDGPIFNGTTFSGEYFFQEVNFAGNAQFDGTLFTEGTPVEVSAHLDGQSRSASP
>NC_017186|6405357:6460869|6449613_6449934_-|WP_013227615.1|DBSCAN-SWA
MTGGDDELAELSVRVVLYRRDQDGELKPVYPDSDGLLESATVLAAPINVPAAVVRALLDSEVPADFAADPWLNRHRALVFTDGQCRVAGYELRYHDKFGVYASEET
>NC_017186|6405357:6460869|6405357_6406425_-|WP_014467348.1|integrase|DBSCAN-SWA
MAAQQSRCADRADDLAAARLLLERLGVDPADLVADQSECPTSVPTFSEYIPVVAAAVSLGTRSTYASYWKHLETSWGSRRIDEPTPSEVKQLAEEVKANAVSRNNFRGGTGAAESFIAAARCLYHHAEDDRLITRVANPAARVSKPRRLPSPRRALTALELTEINGVAGSTGDDPELDSLLLRLHTETACRRGGALQLRPRDLDRHQCLIYLREKANTSRWQPVSPSLMAHLISHGEGRGAVDPDEPLLRYRRKRPITRRRYDHLWDRVGRHLPWVAHQGISTHWLRHTTLTWVERTHGYAVAQAYAGHQSSTTLNQAGTTATYVKASIHDVAAALAVLTREPHPVAGGGSLGEA
>NC_017186|6405357:6460869|6420802_6421060_+|WP_141748472.1|DBSCAN-SWA
MKRVARTTRTELEVIRDAGGRIRELHPLNRGHFGQHDTGGKIVLATEPTIARTSPSLGFTSPHLPAASRIDKATGSLPRCEDGTP
>NC_017186|6405357:6460869|6413266_6414283_-|WP_013227596.1|DBSCAN-SWA
MTATPLSAGMLVEAALDVPAWDGERADWRARGMAELLVQALATGDGDLADAVLRVVPSIGPVGWRFAERVSALGDISVSRFGIRPMPSMRYVPTRPIATRLPDAVQEAAGRLARLLDRREAPEPDGPGYQRRVATTARRVAEVLERTAVDRPAAVRGHRCADLAIPAMLTWRGWLATGCGPLFAATPRLITEAQLRVWLGLHVGTHLDLLARSAAPVRWQFGRRLLAAEALATAVEISAYLISERPDEIAVLRAGLIERLSRLPGIGEWGPRAAASSPSMASAATMSSPEFVALPTLACAYVAGPFVLAEKRFRSRGVPQEYADALDRRWRRAGLAHG
>NC_017186|6405357:6460869|6430525_6435712_-|WP_013227606.1|DBSCAN-SWA
MIEEPVELAKDLTRLVLQQADSVVAMYLAGAKYEQPVTREQKESIESIIAADYDGRTVVELLQNGHDAHDSGRSDGKLEFLLDENEGAHGVLYAANGGRPLDQENFRSMCLIARSSKRPDEGIGNKGVGFKSVLQLSDCPEVYSARHEGAGRFDGFRFRFGRPDDFDGLAARSKENWPGLADELRENVSTLKITVPLFETPTVVEDFARRGYSTVVRLPLRSASTRDHARDQLEELAHDEVPFHLFLTRVAEIVVRSQAGETESRRRLTRSTRARRGTSTLSVEHIDLGEQREYVILKRVVAETGIRAAIRASLDDNAIGSGWAGWQGAAEVSVAVPLGAALSQGRVYTFLPLGPGSPCPIAALVNGPFFTRLDRRDVHESIPLNDFLFAEIAALCADAVVAACRGDLELPDEVPLDLVCWAPGWTQRLIAALQALGVELVDLPVLPPLQHQGEGLTFKSALLWSYRGAVFTPEAVTAAGETRLIRYSIDEQRLRRLRKLAKATDHPVEARPADLAGFAETLADDLLRRGESYEVWAGFYDDLSVVLTDVTLIRGHRVFLTEGGILRTSIEDDDLMIYFGPVRGEAGELPELPEVVRDRLAFMPADINWSDERGQRPGRRWLEAIVREYRTDAVLDLIGKVMYDTEAEEVRSACLRFAFDLWQDTPAERRATALGRAGLLVRTRSGWKAPAEAYFDAGWGGPAGKIDRQLADLVKATALISGTLAAVGQSLLFKPELGEATLDDVRTFFEALGVRHGLVPLTVRASRFQLQGKTLKNPRTVPVFPIEISVATQAAWRELAARHSGKPSYDSTRYQPAGGIAYLPGQEEWSEFDDTARRLYFQLVLHGLEVWPATTLWTYFQASSDSVRVTWPTFVAAFLVRADWIPQTTPGDRGKQFFRPMSDAWWVGNTDTPDYLSADPAAFRSLLTDRVRVHLQRLGARFWDDPGTAADRLRELTSVVRLRGPRMSLVRNAYEQAWRDLADRGEEVPHEVIVSVHGSLGVLDLDQEGPAVYTLDEDGAVQAALLIQTPLPMLAVRSPGVAERVRQTLVSDGVSRLRAASAATVQVLADGTDPLTMKSQPLTDLGGDWLPLLVDAIADRRRQALPAAGITVGATAGALRDSVGLVLADSITAVIDGHPVDQEFAPSSMRVVSPEGDPVIVALRGTGEPWVVLQSAAAALAEFRGGPPIADSVRLALIDLTQRCGDRTPTLDDLAVVLKLPVTELQSLAGDAASTRFEVTPVLGLLACLDPGIAEELQGDRIGDQQEMLDWLSRRGFDADEILALAGQNDLLDATRQLDIPLAQANAGLRAVNLPLLHNDIGHRQQFDAYLQRHRPELQDQLRDRFVARFRRGEPLDEYLRLRDLPGLEPDSTWLDTYWHLPDHVVQARLDLWLASVGEPLAGKDRLPPVDELRDRGRRAVMRTLERARIVIEAWLQRNTAGTGARPAEIAGTLEKMVQTGFLDFEVPRTSAVVVWLGEHGQWPVGMPATTEPRQLDLTDGDLKAAESRLNAGHDTAKRRTETVRYAGKTYSTGTEDRDSLIRAVRESVPQGVLDTSATADRMAPLPPSSSAVSGSSSGEWRAPVLSAEKTRLIGLAGEIVAGEWLNAKFGLQPEDTWVSGYRAEYLADGKGNDSCGYDFLVTLPDRTLLYEVKATTDNARQFTLGESEVRRANALRPHEEYHILFISNVLDPDKMRLRVLPNPFSVGGLASYQVVGRSLNLRFRSAD
>NC_017186|6405357:6460869|6447443_6448040_-|WP_013227613.1|DBSCAN-SWA
MSTPVAQRRDGFISALYALNAGLESSIPKRRSEARQVLARLRRSLVTARPEPAAYEVVFRHDPPESEQDAWILVAGLFALHPKASRRGDRSIGTAMQALQDKRGDSATRRFEQLLGRDRAGLPHHLRQIVRLLAAEGIPVNYAALLDDLVVLMGDKYSEDTAHRIRLRWARDFHRKRKTTTTDNGEPAPAPTTVENPA
>NC_017186|6405357:6460869|6446316_6447447_-|WP_013227612.1|DBSCAN-SWA
MIIELHLLQSFPVSNLNRDDVGQPKTATFGGSTRGRISSQCLKRSARQLFTDHGLTDTETGIRTKRLRNEAAALLTKRGRDEQEAAGVVTAGLEQLGFGVDQDKGLTEYLLFVGTTAIEHLAGYCDDRWDTLAAVAAAKDGKKKPAKAKPDKNDLAEAKRMLDATRVADVALFGRMIADNKDFNVDAASQVAHALSTHAVATEFDYYTAVDDLKPEAESGADMIGTVDFNAACYYRYANLDLDRLRQNLAGDDELVARAARAWLGAFIHAVPSGKQNSMAARTMPDTLLGVVRDGGAWNLANAFLKPVTGEDIMAASTASLTQHFQQLRAFYGSSSIRAAVAASVTGQLPDMDGTDTAASIDEFTSRILAAGTTPA
>NC_017186|6405357:6460869|6424512_6425646_+|WP_014467354.1|DBSCAN-SWA
MSLTDEQWDALGLDRVVVRDRAEFFIGYAGSEAPLFDVDGVIDAFRDGPLGDETDQKVAKFTDTDDAGPAGLLRRRMAEAAGRPGRRPWARTAERADALRHAAQAALLGDTREGRNLLLQSASLYRELGLPFGDFLSAAAVGPGDAAFEAAGQLRSIIFGSETAPEARRVDEGYFSLPRRLLAPAQQIAVLFTALSSADGVDGFGIGIDLLRRASQATQATSVGVTGRPVALWWECGVRLAELTYGRPSARDDLRTTIAELATAHGQALRTAQFDRYHWPRALSKMDLVDLDLTGLTAISNRVLRQLGEPEWSMFEDFRDLTPLSQVSVQVGIRLSGPGRPRTPASGPSPSPEPTPGPAAASDYVPESRSPSLWARS
>NC_017186|6405357:6460869|6421244_6421628_-|WP_141748471.1|DBSCAN-SWA
MVKKKGQRGLRGLVGTPMGGPRSKRRTSTPPAERSDHHCPDCRAVPGQPCRTIASAVGAALQLGKVRPTMHARRPSGPVEISSIDPNRPAFVPRNQRPDAELGRTDRLGQDALPRGQRRNVTPRNFY
>NC_017186|6405357:6460869|6426349_6426904_-|WP_013227604.1|DBSCAN-SWA
MLGINATLADIEWDEDRTPQAEAAWERLGSHLGFTSTRPEKLYGKGPDNLWALAGDRHAVVEMKTGCTTDMIAKKDVDQLGGSVRWDQDNHPGITSIPGITSIPIMVHPSRIVNHQGTPVPGMRVITAAKLDELKTAVRSFAVALADGQGRWYDEQGVSVQLTQARLTAGKFLNAFTEVNLVES
>NC_017186|6405357:6460869|6442309_6443341_+|WP_013227609.1|DBSCAN-SWA
MRKTVRVLPDMDRWRQLISEYGQLQQLTGHTPQTRGQRFNNMIAELLQCWGIQATANVRAAGEIDVAFAIDGVRFVVEAKWEKTKADTGRIAKLQKRVRQRLSGTYGVFLSMSGYSPEALDDIADGDRLEVLLLSIEHWEAMLGGLVPPQELFNLVRDRASFYGEPYTPLAQLFAPAEIPDIRLGPPSEMTDGPLLEAVDGLDAQVVLSGIESGQLGIACHGQNSLLVTTEHGILDVDFEAHTVTMAAPVPDCQRNVLANEDGSIVFLRRSGVGLFRDGQITTVGGGLSGNSCLCRHPDGSLWVFDNGGLLDHSASVTRLDDKLGLQKRHKINYSPANAFTSA
>NC_017186|6405357:6460869|6453003_6453834_-|WP_158314388.1|transposase|DBSCAN-SWA
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA
>NC_017186|6405357:6460869|6425600_6426026_-|WP_141748470.1|DBSCAN-SWA
MSPRERDAHELRQLARETADQLASFAHIFSAADRRNDRVTPPELFTLAGLLEDAAAVLGEDARVKPLIFSFKDTIVPQKELNFDIAYRYLTPIVRAIRSRYNLPGSPHASPASKPRRRVDVRIDTDRHDRAQSDGDRDSGT
>NC_017186|6405357:6460869|6459156_6460197_+|WP_013227618.1|DBSCAN-SWA
MGRAWHQPDLPPGPVRALKTALHRLHAKAGYPSVMQVARWIARNWTEEDSSRPFSTTTCHKALITGELPNRNVMLWVVDAFIGLGRIGDEEAILDSFERLWQDAHDDRVHPRSATEGPGAPTMPRSDTGTQPDPNGDLSLASGQEFHHHLGEFVDHLTQFAVLREADGRRLTIQILNDDPDCSVAVAEHSTARPHLFALVLACHKQPGALIRLLDVIDMLTGSDGPPTDQARAMLKVPASPGPISQADDLGEVVDALERVPELRELAGRNLAIEMLTESLGIDLGVEEIPITRPHIAAIAKACIVHHPGTLVKFAEAVSVISPNSKSTVFALEKVKNYTRMRAGAG
>NC_017186|6405357:6460869|6417114_6419088_+|WP_013227599.1|DBSCAN-SWA
MTGEHSEGRQSLEHDLVVVLTSVLTRACTGASNPEDAALARKLVHDLHQPKVDKFVRASAVAAVMAAFPPQEAPDRKLVLAARTSARVLCEPDQPEPWILLGGQALALLSAGGHSDQPAVDFLLAAEAMRKVEQYNLATWAIRRALAEGGLDQQRLVHAHLMLWLVTHDPETGAQARAGAALLPEDNVVRRAIEATVWPGSPGTGDAGVLDSRVTGALRMLKVLDGIIGEGHDDDMLRGLRQAIEAYSRPTLDLGQARAGLTRAIGFWRSRRGLGQVPRAATAGLDAAITLLLIDATSEQVILLCELLEALADAGLTRDQVDWAADSMSPAALQASLARRASQEPVWPDLELLFDRLADRHVLLVHPRRGLGDADVVVLYLRPPGGYLLNRVWLDAEDQRTLDRLSGRPLSGLRSVSQDDVDRLAGKIISPAFAEALDQSSTQELVIVPAGALATVPWSSATVHGRSWTTRPITVAASMSVAAAVPPIASARRRVHAIIDSSVQGGKELLSVLKEHATVHTKLPAAPHPDDVLVIFAHGTGAGLEYRLHLPDGPVDVLSLARARLPQRVILAACRSGGPPPEAFPLAVPTALLLAGATTVVAGLWPLPAASTARILADALLEPESGLADAVRAAIGRSGFTTVIDRAGLAVFGRDDR
>NC_017186|6405357:6460869|6454593_6456450_-|WP_013227617.1|DBSCAN-SWA
MSDGDVMVFNGLSRFAVPVEKPVLLDDDGFLLATSDARWRSGEAVSPVPVAELPTEVVSFALLAAGGAGKTVTFTELANAEPDARRIDTSALTIDGLERELDDACFHESAVYLDGLDQAASVEARLFPWLERYLTAPARRGMRSRLACRAAAWDAVLGRALFQQMTAFTVWKLAPLDRDTASKAVEHAIGVSEVDSAAFMKALVGAKLGRLSGCVGQLVAVARYWNAQGVLPRSAADAMKFEIEYLLRETDERRQPRLPLDRSMRVAQRLGAFTMFAGNQALTVRAVGDRATLPVSDLPSDAEPDQPARTIEPLDYGAVLDTALFDSGPAGSVMFRHQRYLEYLAAAYLVQRGIRAGQIPVLLGVHVNGLLPTPRIGVASWLAALAPDLVAQLFIDNAAMFASAAAVVELPSDEARAALVKGLLEAAARDDAEPDWRLDRTGLLHAGLTEQLAEYLGRGPANAPQLWWIARLAAAGGCRTLAPALARAALEPAWFGYVRRAAVAAVADLGEDDLQLSLRQLLAEPTDTDPDADNEVRAAVIDALYPRLLSTVELTQALRPHRSMLFGGYLQSLRELPSRVPENDLADFVAWLADHAWRSDVRDDDQFEDLYAGVIKRA
>NC_017186|6405357:6460869|6449930_6452210_-|WP_013227616.1|DBSCAN-SWA
MLDTAAVAERLAPLLLRGRVRSELAAAFGVLGDAWGWTAFLCAVHDLGKYSPTFQALNFPLSSARLGSWAVRDLELVAKLHGVPRRVDTPHGLLTALHLQELLVSWGASRRTAVMIAAALGGHHGHFPAGEVVAQARREINAHGERVWAEQRTTLVAELARLRGLPDPRTLDWAQVDLSVPAAVGLAALTTVSDWIASDTSNFAFAEDEVDLAAYAKDAAVQAEAAVDRLKMSSWSPPGGARFDELFGQSPRSVQEVIERVTADLEGSALVVVEAPTGEGKTKAALQATATMVSQFGLAGSYLGMPTQATSNQMFAVMQAMLTRLGDPTTVSLVHSAAREVLAEPAEVGVDEPGTLDAEAQAWFTRKRSLLSVLGCGTIDQALKGAFRSGHVFVRLAGLANKVVVFDEVHAYDTYMSTLLQRLLMWLGALGAPVVLLSATLPSSRRAELIAAWQAGYRGCYPQEINVPPASKPYPRVTVADTAEVVDHPVEISELNRDRVVHLEHVPDERVVDWLLVAAQGRCVAVVHNLVRRATETYAELERRIKELPEEDRPVLLAINGTLPTGARRRVEQELQGFFGENGMRPRRAIVVGTQAIEQSLDLDFDALITDLAPIDLVFQRAGRVHRHRRDAARGRLTVAITGVVDTPAGPQFPAYLRTVYAPIVLMRTWAALKDLDRIESWTTMAQLVDEVYGDQVACPRGWEAAWRRESDRLAVAQHNDREAAAESYLPQPHMVEVLSELTERPRALRTRKSTGRKR
>NC_017186|6405357:6460869|6409787_6411020_-|WP_013227594.1|DBSCAN-SWA
MRVLIAGVFVGCPMAISAACGVDEPTCDETLPAYQAAAPDPGDPDSRLEVLVDHTADAPRIKMPAELGEKLHDMLDAHTGGGRVLIDVGQIQGRSDGAAFWKQTNRVARYRTDVDADRDGYVRRVLGCLDAWTSSLVPQQPDSSLLDALQKVSRQIGTEHGPVSVVAVSNGLDNTAPLDLRVPLAGDATPESVAKMLAGDAEIPGLQGVDVQILELGQTSQGRRQMTEGEQRWIVSVWGEILKAAGVAKPRLERKSGDILDGAPANVPADAVFAAAPPQPKPPVGTGSVSLSAQALFDPNSPVLAPAAEAVLRPYVTILQGPGAHATITGHTATWGPIPGRDLLSVQRAEAVRNYFIEQHVPAEALAPARGVGSSEQVVNDIDPAGNLIEQAAQRNRRIVLDIVTPTKGR
>NC_017186|6405357:6460869|6415153_6417118_+|WP_013227598.1|DBSCAN-SWA
MTDEVALAALGEVLSRRCWSTQQRDDAESAQRIIDEIARSDIDKTVLVALLGGVRAAFLPDELTDELAEAAATSARQLMPTRLADTERLAVAAALGVLADSGRPARRTADFVAVALSAHHIEQDQLGRWAAERALAAADDLTPSQETAAAFVLALISQDRADILRAYELAATLPPDDPRARQAERLRATLHPDLPSQLEPAGDAVRAGNREAAARSLAEDFGRLHDETGNPVVGGLAEAMAALGEREVDVEAARRGLTTVVRALRSRQRYGQVPAVARTGIDMIASMLTIDATAATADLLAEFLEALADAGLSDIVLDEHLDVLPALVQARFADVASALPTWPDLAGCVHGLRGRPALLLRRQRMFATKNASVLSMYVEPPDSVAIKSTLLTDADAAVLRRFGRARPAELRATDLREVNRLISSLLPAALLERLADAGRQPIVIVPDGELWSLPWQAAPVFDDVTVALTPSLSVHARLAPTSGVVRTVVTLIDPGVEGADEVSAALEAAQRSGTLTVAHYSPGVTQTCDLLLVFAHGEGTGLSFRTGTAAQPVPALQVATEVKAGAAVVAACRALAAPPVSFPITLPSAMLLSGFSTVIGGLWLLPAEPTARIVADLIHRLASGTELVTALTAARASVPDLLDQRWGLAVHGLT
>NC_017186|6405357:6460869|6414279_6414990_-|WP_013227597.1|DBSCAN-SWA
MTFSMPIDESRRHLHTTGFVLLRGCEFTDGRTVDRGAVGDLMSVFGKISARDGGTAIWPVRPATTDVHATFSVRAGAAEWHTDAAYRDVPEDLVALLCVRPAADGGVSRLLHQRHARTGLDADVVTALRQPSFSWRPPAVFGGGSIRQFPVLASDTVRWRWDNLEVARPHNAVAASFREHLAAASGALDLPLQAGDVLVFDNRRVLHSRTAFTDPRRHLLRVRLWTRAETRAGEQR
>NC_017186|6405357:6460869|6427890_6428496_-|WP_013227605.1|DBSCAN-SWA
MAFPNRWTASSSAAAALANSPTRRIREVQRIEQGMGRGVRDSDDHCAVLLVGSKLAMATRDPDWKKLFSPATRAQLDLSNQVAVQLKGQGLDAVRSALTACLDRDPNWVERSRRALAEIRYLDAGTIRPEAIAIRAAFDLASAGQYSAAADEIQRAINGIEDTLLRTEGQLPAPRHPPSSPSSSKASPSRRTERCSSRWSE
>NC_017186|6405357:6460869|6411162_6413253_+|WP_013227595.1|DBSCAN-SWA
MSGRAQDLTPEAAAELLLESFRGEGYRKLDVKACAHVLGIGKSSFTSRFGRKRAMMIITALWCWLENPVSPCTERHTVGEARRLLHDVAENIAGFLHRERTLMVQLVYGLSDISNYEKNDDEKAWRSESFGEPWATVLRAARTHNRWVGFAPRLREGVEVAARAVGHLDTAAHQSMADALSDLLLRVWWQNTHAPATVIAEQVTGLWFSGMLLPATGPWVGRAYAAEQQLLRALRPEHAPTWEIASRTELGTALISGQTLWRRALREFGLALTEFSQLEDSLRAQPSPLLIGSLRSRHGQCALRYGDYPQAQTSLTEALREARRLGNEHDIARARTNLAELYMRTGRVTEALTLARQAVAARPLRPVWSSPVPRLWDAAVVSTVVLTRAHLHAGQVTDAVRLAEDLLEVIDGEGGRAVAPDGPTAALARATHGRALLAAGHPDLARRSVTDAVTAAANATGRHSLLTRQARTLEARCYLALGDPESACRILDELVQDENWVAEHMSFRHALSVRVWLGAAWLAAGDAARSAQVLDDGLALLRRHLTDPDPQSIEYRRVAAVTAWQLDQAAAVADLERLVDASSSTPVLPRHVDLLHDLGQAYAARGEGHRARQTFRRALREGETGIDPAHPSVLAVRVALARLQLDDSPEHAAKLLEPVLSDRPLAHGLTALAKTHPLLSAARSLRDRIAKSSGTQ
>NC_017186|6405357:6460869|6453920_6454244_-|WP_013223344.1|transposase|DBSCAN-SWA
MPPRKRRSYPAEYKVEAAHRVIDSGRTIAEVARELGLDAGMLSVWVKDERRRVTAAEVHGENPLEAAERAELLRLRGQVAELEKDNAFLVKASAYFAAMQKNRPGSL
>NC_017186|6405357:6460869|6408198_6409161_-|WP_013227593.1|DBSCAN-SWA
MQVGRTDWGHLVIGMTGGFFLGLLSPVVVIVASHVLAEHVARLRHGMLKAPAYVMSSASGRSRHLVRAARWITRHLPGLGATLILTAASISFGLAASARLGASQVSDGTLRNAMAPVLVLLFVTLPWVVFLAHLYAENPKLEQLEALRAEDEARPPTALVLAEEAAEIAHDNCQRAKEEAIAAAARRDTAWDAVYRTVHDVLSEVDYYLAQASNISLGVRALVTWPDIRTGEPRRPLTAELVKALAEVSVDLSPLEPHLAQLERLAPGESQAQEIRALRSQARRMHGIVVLAPVIGPKTNGSVPKEVAEDIIQSEEKPQA
>NC_017186|6405357:6460869|6419897_6420623_-|WP_013227601.1|DBSCAN-SWA
MTSPIGKSTASGTRSLATFQGQAFLPVQDRVRRTGITRWAELAQLSEITQWEPAWRALRTCSGLDDDAFVSFLCDFEFKFGILLVDPLLSPDQDPVSRDAEHLAREMFSIVRDPAQPARLSRDELLARLGWTDRLLYRHPGPAGSGKSTLLADLILPGRVVRQRLLFLFVGIVRKQVLEVDWNQAKAAIYNRATKYLAVYTTRPTKRAIPAVAVRVANVADAHAIVAAAEAASAAPRLDIV
>NC_017186|6405357:6460869|6423865_6424516_+|WP_014467353.1|DBSCAN-SWA
MIVQWCCKGMAKLPEREAERILTGGTGIRCRSWLTVAPKPFPLGKNLDRLTEDNLDRHVNKYSDPDPVTGAPFHDVTPFISLSAGCVDRQVAIERNETHSALRTALTFATTDYSQPGPNWPRCAGWVFYCYVLTGVNRAVSIPSVAEEYRELNLGRSYSRWQPQGEVMAKINVPSRQILCAVHWTPLPSGESKWDEVLWNLRFTHPAALLGERNML
>NC_017186|6405357:6460869|6437865_6438249_+|WP_013227607.1|transposase|DBSCAN-SWA
MDRGTEAWLRSLTFDRVGVRLAFEEAFDAVLATRAQRARLDAAITELAAPPVFAPVMGRLACLHGVSTLTAFGLVTEIGDWRRFTGASIGAYVSLVPADSSSGEHRHQGAITKTGNSDGQRLLVEAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
6399763:6399783	attL	NA	NA	NA	NA
WP_014467348.1|6405357_6406425_-|integrase	site-specific integrase	NA	NA	NA	NA
WP_013227592.1|6407425_6407653_+	DUF2637 domain-containing protein	NA	NA	NA	NA
WP_155258934.1|6407905_6408052_+	hypothetical protein	NA	NA	NA	NA
WP_013227593.1|6408198_6409161_-	hypothetical protein	NA	NA	NA	NA
WP_141748473.1|6409172_6409784_-	hypothetical protein	NA	NA	NA	NA
WP_013227594.1|6409787_6411020_-	OmpA family protein	NA	NA	NA	NA
WP_013227595.1|6411162_6413253_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_013227596.1|6413266_6414283_-	hypothetical protein	NA	NA	NA	NA
WP_013227597.1|6414279_6414990_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_013227598.1|6415153_6417118_+	hypothetical protein	NA	NA	NA	NA
WP_013227599.1|6417114_6419088_+	CHAT domain-containing protein	NA	NA	NA	NA
WP_013227600.1|6419104_6419881_-	hypothetical protein	NA	NA	NA	NA
WP_013227601.1|6419897_6420623_-	hypothetical protein	NA	NA	NA	NA
WP_141748472.1|6420802_6421060_+	hypothetical protein	NA	NA	NA	NA
WP_141748471.1|6421244_6421628_-	hypothetical protein	NA	NA	NA	NA
WP_013227602.1|6421783_6422272_+	hypothetical protein	NA	NA	NA	NA
WP_013227603.1|6423308_6423869_+	hypothetical protein	NA	NA	NA	NA
WP_014467353.1|6423865_6424516_+	hypothetical protein	NA	NA	NA	NA
WP_014467354.1|6424512_6425646_+	hypothetical protein	NA	NA	NA	NA
WP_141748470.1|6425600_6426026_-	hypothetical protein	NA	NA	NA	NA
WP_013227604.1|6426349_6426904_-	hypothetical protein	NA	NA	NA	NA
WP_085931694.1|6426959_6427791_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_013227605.1|6427890_6428496_-	hypothetical protein	NA	NA	NA	NA
WP_080582935.1|6428988_6430182_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_013227606.1|6430525_6435712_-	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_013227607.1|6437865_6438249_+|transposase	IS110 family transposase	NA	NA	NA	NA
WP_013227609.1|6442309_6443341_+	restriction endonuclease	NA	NA	NA	NA
6441361:6441381	attR	NA	NA	NA	NA
WP_014467360.1|6443991_6444237_+	hypothetical protein	NA	NA	NA	NA
WP_013227610.1|6444968_6445619_-	type I-E CRISPR-associated protein Cas6/Cse3/CasE	NA	NA	NA	NA
WP_013227611.1|6445609_6446320_-	type I-E CRISPR-associated protein Cas5/CasD	NA	NA	NA	NA
WP_013227612.1|6446316_6447447_-	type I-E CRISPR-associated protein Cas7/Cse4/CasC	NA	NA	NA	NA
WP_013227613.1|6447443_6448040_-	type I-E CRISPR-associated protein Cse2/CasB	NA	NA	NA	NA
WP_013227614.1|6448036_6449617_-	type I-E CRISPR-associated protein Cse1/CasA	NA	NA	NA	NA
WP_013227615.1|6449613_6449934_-	hypothetical protein	NA	NA	NA	NA
WP_013227616.1|6449930_6452210_-	CRISPR-associated helicase/endonuclease Cas3	NA	NA	NA	NA
WP_158314388.1|6453003_6453834_-|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-30	33.0
WP_013223344.1|6453920_6454244_-|transposase	IS3 family transposase	NA	NA	NA	NA
WP_013227617.1|6454593_6456450_-	hypothetical protein	NA	NA	NA	NA
WP_014467361.1|6456895_6457315_+	hypothetical protein	NA	NA	NA	NA
WP_141748524.1|6457614_6457962_+	hypothetical protein	NA	NA	NA	NA
WP_141748525.1|6458652_6458913_-	hypothetical protein	NA	NA	NA	NA
WP_013227618.1|6459156_6460197_+	hypothetical protein	NA	NA	NA	NA
WP_013227619.1|6460320_6460869_-|transposase	transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_017186|8559516:8633698|DBSCAN-SWA
CATGCGCCCCAGCACCCCGAAAACGCTCGCCCTGCTCGCCGCGGTCGCCGTTCTGACCGGGCTCGGCACCGGCACCGCCGCGGCCGAGCCGCTCACCCGTGGCTGGCCCGCCCCGATCGACGCCGCGCACTGGGAGAACCAGGACCACATGACCTGGTCCGACTACCGCAAGGTGCCCGGCACGAACTGGGCCGACCCCGCGCTCAAGCCCACCCAGCGCACCTTCAAGGGCGCCGTCGTCCTCGCCGACTACCCGGACCAGGACTTCGTCGTCACGAAGCCGGCGAACTCGACGATCTTCGGCAACCCCGCGCCGACGGCGGCGAACATCCCGCGGGCGAACGTCGCGCAGTACTACCAGGACTTCCTCAACAAGCCCGAAGCCCTCAACAACGGCCACACGATCAACGAGTACTGGATGGAGGACTCCGGCGGCCGGTTCGGCGTGCAGCTGACCGCCTTCGGGCCGTACCGGATGCCCGGCAAGTCCTATGAGTACGGCATGGAGTTCCAGCCGAGCGCCTGCCCGCCCGGCGCGAACTGCGCCCGCGACATCCGCAAGGACGCCGGGGACGCCTGGCGCGCCGACGTCGGCGACACCGCGAAGCAGTTCGACTTCGTCTTCTACCTCTCCGCCGGCCAGGACGAGAGCTCGACCTGGCAGGAGTTCGGCGAGATGAAGTTCGGGACGAAGGAGAACGTGCCCGACAGCTTCGGGCCGCCGAACCACGACCTGCCGAACTACGCGGCCACCCGGTACGTGCCGTGGACGTCGTGGGCGTCGGCGGCCAGCATCTGGCCCAACGCCCAGAACGGCAGCTCGGTGCAGGCCGAAAGCTCCGGGCAGTCGACCTACGCCCACGAGTTCAGCCACATCCTTGGCATCGGCGACAACTACAACAACCCGTTCGGCGTCCCGCCGTCGCGCAGCTACAGCGGGCCGTGGGACATGCTGTCGCGCGGCACGTTCAACGGGCCCGGCGGGCCGCACACGCGCTGGCAGATCCCGGCGACGCAGGGCAGCTCGATGGGCGCGCAGCACCAGCTGCGCAACAAGCTGAAGCTCGGCATCGTCGACTCCGCCGACGTGCTGCAGCTGGACCGCACCGAGCTGGCGGCTTCGGGGCCGGTGTCGGCGCGGTTGACCGCGCGCGAGGCCGAGGCGCAGCCCGGCGCGTTCGCCGGCCTGAACATCAAGCTCACCGGCGGGGACAAGGCGCCGAAGTGCGACCGGTCGAAGGACCCGTTCTGCGACGGCGGCGGCTACGACAACTACACCGTCGAAGTCGTCGACCGGATGGGCTCGGACTCCTTCGCGCCCGACTCGGGCGTGCTGATCACGAAGACGAAGAACCAGGACAACGCCCCGTTCGACTGGGTGATCGACGCCAACCCGCAGGACATCGGCATCACCGACTACACGAAGCCGGACGGGACGCCGGTGAAGATCACCGTCGGTGACTACCGGCAGCTGAACGACGCCCTGTTCAAGGCGGGCACCGAAGCGGCGAGCCCGTACGAGTACACCGACGAGGCGAACCGCCTGCGGTTCCTGATCACGGACGTGGCCCGCGACCGCCACGGGATCCTGTCCTACACGGTGACGGTGGCTTCGCTGGACGGCTCGGGCGGCCAGGCCCGCGAGGCGGCGCTGACCCCGGCCCTCCCGGCCATCGCCCGTGGCGGGCTGGCCACCTGCGAATTCGGCCTGCTGAACACGGGCTCGGCACGGGGTGCGAAGGCACCGTACGACACGGACACGTACCGCTTGAGCGTGTCGACGGACACCCGCGGCTGGGAGGTCCGGCTGCCGAACGAGCTGGCGACGGCGAAGTTCGGCGGGTTCGCGAAGGTGGCGGCGTACGCGAAGCGCGGCCAAGGCGGTGACCTGGCCGCGAGGGTGAAGCTGACGGCGACGTCGGTGAGCGACCCGTCGAAGACCGCGACGGCCAGCTGCACGGCGTTCGGCTTCTAGCACCCCGCTGACATGCAGTGAATGACTCATTCCTGGCGTCTGACGACAGGAATGAGTCATTCACTGCGCGCGGCGCGCCCGGCACTGCGTGCGGCGCCCCCGCGCGAGGCCGGATCAGCCCAATCGGCGAGCGGTGACGAACCGGGCGCGGCCCGTCAGATCCGTGTGGCCCTCCACCCCGGTCAGCACCCGGCGCGCCCGGACCAGGGCCGGGACCGCCGAACCGTGCGTGTCGTCGTGCTCGATCGCCAGGCCGCCGCCCGGGCGCAGCAGCCTCGCGCCCGCCGCGATCGCGTGGCGGATCACCGCCAGGCCGCTCTCCTCCGCGAACACCGCGCGCGGTGGGTCGTGCTCCGCGACCTCCGGGGGCACCGGGGTGCCCTCCGGGACGTAGGGCGGGTTGCACAACACCAGGTCGACCAGGCCGTCGAGCTCGGCGAACATCGTCGGGTCGCCGATGTCGCCCGAATACAACCGGATCGGGGTGTTACCCGCGTCGGCGTGCACGTCGGCGTTGTGGCGGGCCCAGGCCAGCGCCTGCGGGTCGATGTCCACCGCGTAGACGACCGCGTCCGGGCGCGCGTGGGCCACCGCCAGCGCCAGCGCGCCCGAGCCCGTGCACAGGTCCACCACCACCGGGAACTCCCGGCCCTGCAGGAACTTGACCCCCCACTCGAGCAGCAGCTCGGTCTCCGGCCGCGGGACGAACACCCCGGCGCCGACCGCGACGGTGATGTCGCCGAGCGCGGCCCAGCCGGTCAGGTACTGCAGGGGGATGCGCTTGGCGCGCTGCTGGACGAGCTGGCCGATGGCCTCGATGACCGGCGGGTCGACCAGCGGCACCATCGGCAGCCGGCCGCGTTCGACCCCGAGCACGTGCGCGGCGATCACCTCGGCGTCGAACCGCGGCGAGGCCACGCCCGCGCGCTCGAGGATCCGGGTGGCCTCGATGATGGCCAGGCGCAGCGGCTGCCGATTCACTCGTCGTCCTTCACCTCGTCGAGCCTGGCACACCAGGCGGAACTCCCCCGTGAGGACACGCGCCGGTCCCACCCGACCAGCGTATCGAGGCGCCCGGGCCAGTACCCCGCCAGCGCCGTCCGGCACCCCGATCCGGTCGTCCGTCGCGGCCCGGCAGCCGGACCTCGGCCCCGGCCGCCTCGCGGAGCCGGCGCTGCTCGCCGACGACCTCGGCCACCGCGCCGCCGGGCCACCCTCGACCTGCTCGCCGAGCTGTTCCGCACCGGCCGCGGGTCCTTCACTCCCCCCGGCCGGCGGGCCGGTGCCGGTCATCGCCGGCGGCAACGCGAGGGCGGCGTTGCGGCGCGTCCCCCGGGATCGCAGAGCGCCGGCCGGCCCGGCCGCGACGGTGGGCTGACCCGGGTCCCGGGATCGCGCCAGGCCGGATCTTCTAGGATGCAGGGCACCGGGTCGGGGATTCGCCTGCTCCACGGCGCCGCTCGGACCTTTCCGCACCGAAACTCCCGGGGAGCCCCGCAGTGCCCACAGAGCCGATCACCCGCCGGGTGGCGTTCATCTTCCCGATCTACAACGAGGAAGAGAACATCGACCTGCTGCACCGGACGGTGGACGAGGTGACCGCCCCCCTCGCCGGGAAGTACGACTTCAGTTTCCTCTACGTCGACGACGGCAGCCGGGACGGCTCGCTGGCCAAGCTCACCGAGCTCAGCGCCCGCGACCAGCGGGTCACCGTGGTCGAACTGTCCCGCAACTTCGGCCACCAGATGGCCGTCACCGCCGGGCTGGACCTGGTCGACGCCGACGCCGTCGTCATCATGGACAGCGACATGCAGGACCCGCCGCGGGTGGCGCTCGAACTGATCGAGAAGTGGGAAGAGGGCTTCGACGTCGTCTACGCGCAGCGGCGCTCGCGGCAGGACTCGGCGTTCAAGAAGCTCACCGCCGGCGGGTTCTACTGGTTCCTGCGGAAGATGGCCGCGGTCGACATCCCGAAGAACACCGGCGACTTCCGGCTGATCGACCGCAAGGTGGTCGACGAGCTGCGCAAGTACCGCGAGCGCGACCGCTTCCTGCGCGGGCTGGTCAGCTACATCGGCTTCAAGCAGACGGCCGTGCTGTTCGACCGCGACAAGCGGCACGCCGGCGTCACGGGCTACCCGCTGCGCAAGATGCTGCGCTTCGCCGCCGACGGCATCCTCGGCTTCTCGGTGACGCCGCTGCGGATGATCACGCGCATGGGGTACCTGATCTCGTTCCTGAGCTTCGTCGGGATCCTCTACGTCGGCGGCGTCAAGCTGTTCGCCCCGCAGACCGCGGTGCCCGGCTGGGCCTTCCTCGGGATCGCGATGTTCTTCCTCGGCGGCATCCAGATCATCATGCTCGGCGTGCTCGGCAGCTACATCGGCCGCACGTACTCCCAGGTGCAGAACCGGCCGCTCTACGGCGTCGCGTCGGTGCGCACCGGCCCGGGGACGCCGGTCGAGGCCCGCGAGGGCGCCGACGCGGGAAGAGGCGCACGGTGAAGCTGATCTCGGCGACCCAGCTGCGCTTCGGGCTGGTCGGCGTGGGCAACACCCTCGTCGACGCCCTCGGCTACGCGCTGCTGGTGACGCTGGGCGTCCCGCTGTTCGTGGCGAACTTCATCTCGACGACCACGGGCATGCTGCTCAGCTTCACCCTGAACCGGAACTTCACCTTCCGCGCCAAGGACGGCGACGTCCGCCGCCAGGCGCTGCTGTTCTTCGCCGTCACCGCGTTCGGGCTGTGGGTGGTGCAGGCGGCGATCATCTTCGCCGTCACCGCGGCGTTCCCCGGCGTGAACCTGCTGCTCCCGAAGTTCGCCGGGATCGCGGTCGGCCTGGTCTGGAACTACGTGCTCTACAACAAGGTCGTCTTCCGGCAGCGGCCCGCGGCGGCCGAGCCGCCGGTCGCGGAGGTCACGCATGACTAGGACGGCCGAGCCGTCCCTGACCACCGATCAGGTCGAGCCGGAACGCGCGGAGACGGCCCCGGCCGGTCGCCGGGCCGCCTGGGTGCACGGCGACTACGCCCGCGTCTTCGCCGTGGTGCTGGCCTGGAACGTGGTGCTGATCGCCGTCGCGTACCTGTTCGCGCCGTCCAGCCCGGTCGACGAGGGCATCCCGAAGACGGGCATCGGCTCGACGATGAGCCTCCTGGCGCACACCTACCGCTGGGACGCCGGCAACTACGGCGAAATCGCCGTGCACGCCTACACCGGCAGCTACGCCCCGACGCGGGCGTTCTACCCGGTGTTCCCGGTCCTGGTCTGGCTGGTCCAGACGGTCAGCTTCGGCACGCTCGGCCTGCTCGCCGCCGGCTTCCTGGTCAACCTGGTGGCCACCTGGCTGGCCGCGGTGGCGCTGCTGAAGATCGGGCGCCACTTCTTCGACGGCGAGCGGGCCCCGTGGCTGGTCGTCGCGGCGTTCCTCACCGCACCCGCCGCGTTCTTCCTGCACTCGTTCTACAGCGAGGCGGTGTTCTGCGCGCTGGGCTTCTGGGCCTACCTGTTCGCGCTGCGCCGCCAATGGCTCTGGATGGGACTGACGCTCATCCCGCTGACGGCCTCCCGCATCACGGCGGCGGTGTTCGTCGGCCTGTGCTTCCTGGAGTTCTGGCGGTCGAAGGACTGGAAGCTGCGCGGCCTGCTGTCGCCGAACCTGCTGTGGTTCCCGGCGGCGTTCCTCGGTCTCGGCGGCGTGCTGGTCGCCATGAAGATCCAGACCGGGGACTTCTTCGCCAGCTTCAACGCGCTCAAGGGCGTGCGGGAGTGGTCGTACCACCAGTTCAACCCGAACATCCTCGGCACGCTCTGGCGCGAAGCCAAGATCACCGGTCACGCGCTGCTCGGGGACACCCCGATGGACGCGTGGACGCTGATGAGCCACGTGCTGCCGATGATCGGCCTGGCACTGCTGTTCGCGTCCTCGGTGTACGTCCTGGTGGCGCTGCGCGCGAAGGGTGTCCCGCTGGCGTTGTTCGGGTTCGCGTCGATCGTGATGCTGACGATGAACAACAACGTGGTGTCGGTCCACCGCTACCTGCTGCCGTGCCTGGTGATGTACGTGGCACTGGTCCTGTTCGGCGAGCGCCGCCCGAAGCTGCGTGGCGCGGTGCACGTGGTCCTGTACGCGAACGCGCTGGTCTGCGGAATGATCTACCTGCGCTTCATCACCGGTTTCTGGTCCGGCTGAGCGCTCCGGGCCCACCAGCAGGCGCACGTCCGGCCTGCTGGCGCCCCCCGGCCGCCGTCAGCCCGACTGAGCCGCCAGGCGCTCTTCGCGGTCCGCGGTCGCCAGTGCGTCCAGCACGCCGTCCAGGTCGCCGTCCAGGACCTGGTCGAGGTTGTACGCCTTGTAGTTCACCCGGTGGTCGGAAATCCGGTTCTCCGGGAAGTTGTACGTCCGCACGCGCTCCGAGCGGTCCACCGTGCGGACTTGCGAACGGCGGGCGTCGGACGCCTTCGCCGCCGCCTCCTCCTCCGCGACCGCCTGCAGGCGGGCCTGGAGCACCTGCAGCGCCCGGGCACGGTTCTGGATCTGGGACTTCTCGTTCTGGCAGGACACCACGATGCCGGTCGGCAGGTGGGTGATCCGGACCGCCGAGTCGGTCGTGTTGACGCTCTGGCCGCCCGGGCCCGACGACCGGAACACGTCGATGCGCAGGTCGTTCGGGTCGATCTCGACCTCGACCTCTTCCGGCTCCGGGTAGATCAGCACGCCGGACGCCGACGTGTGGATGCGGCCCTGCGACTCGGTCGCCGGCACGCGCTGGACGCGGTGGACACCGCCCTCGAACTTCAGGCGGGACCACACCCCGTCCACGGCGGCCGCCTTGCTCTTGATCGACAGCGTCACGTCCTTGAAGCCGCCCAGGTCGGAGTCCACCGAGTCGAGGACCTCGGCCTTCCAGCCGTGGCGCTCGGCGTAGCGCAGGTACATGCGCAGGAGGTCGCCGGCGAACAGGGCCGACTCCTCGCCGCCCTCGCCGGACTTGATCTCCATCACGACGTCGGAGCCGTCGTACGGGTCGCGCGGGAGCAGCAGCTCGGTGAGCCTCGACTCGAGATCGGGGATCCGCGCGGCCAGCTCTTCGGCCTCGGCCGCGAACTCCGCGTCCTCCGAAGCCATCTCCCGCGCGGCCGCGAGGTCGTCGCGGACGGTGTCCAGGTCGTGGACGGCCCGCACCACCGGCGTCAGCTCGGCGTAGCGGCGGCCGAGCTTGCGGGCGCGCGCCTGGTCGGCGTGCACGGCGGGGTCCGCGAGCTGCGTCTCCAGCTCCGCGTGCTCAGCGAGCAGCCCCTTGAGCGAGCTCGAATCCACCTCTGCCACCTCTCAGCCCGAAAAAACCAAAGACAAGAAACGGCGCCCACCCGGAAGTCCGGGTGGGCGCCGTGGAAAAAGCTACTTGGCGTCGGCGTCCTTCTTCTGCCGCTTGCCGTAGCGAGCCTCGAAGCGCGCGACCCGGCCACCGGTGTCCATGATCTTCTGCTTGCCCGTGTAGAACGGGTGGCAGTTGGAGCAGATCTCGACGTGGATGCTGCCGTTGGTCTTGGTGCTGCGCGTGGTGAAGCTGTTGCCGCAGTCGCAGTTCACTTCGGTGACTACGTACTCGGGGTGAATACCGCTCTTCATGGTGTCCTCTCTCGTTGGCTCCGGGTCCCCAGTCGTTCCACGGGGTGAACCGGCGCCGGACTTCAGCGGGTAATTCTGCCAGACGAGCTGACGAGTACTGGAACGTACCCCGCTGACCAGCTATTCCCGGCGCGGAAGGGCCTCCCCGGGCACCCCGGGAAGACCCTTCCGCAGGCCAGGACTCAGTCGTCTTCGCCGCCACCGAGGGCGGTCTTCGAGACCTGCATGAGGAACTCGACGTTGGTCTTGGTCTTGCGCAGCCGCGAGATCAGCAGGTCGATGGCCTGCTGCGAGTCGAGCGCGTGCAGCACCCGGCTCAGCTTCACGGTCACGGCCAGCTCGTCCGGGTTCAGCAGCAGCTCGTCCTTGCGGGTACCGGACGGGTTGACGTCGACGGCCGGGAACACCCGGCGCTCGGCGATCTTCCGGTCGAGCTTGAGCTCCGCGTTACCGGTGCCCTTGAACTCCTCGAAGATGACCGTGTCCATCGTCGAGCCGGTTTCCACCATCGCCGTGGCGAAGATGGTCAGCGAGCCGCCGTTCTCGATGTTGCGCGCCGCGCCGAGGAACCGCTTCGGCGGGTAGAGCGCGGTCGAGTCGACACCACCGGACAGGATCCGGCCGGACGCCGGAGCCGCCAGGTTGTAGGCCCGGCCCAGTCGGGTGATCGAGTCGAGCAGCACGACGACGTCGTGGCCCATCTCGACCAGGCGCTTGGCCCGCTCGATGGACAGCTCCGCGACCGAGGTGTGGTCGGCCGGCGGCCGGTCGAAGGTCGAGGCGATGACCTCGCCCTTCACCGAGCGCTGCATGTCGGTGACCTCTTCCGGACGCTCGTCGACCAGGACGACCATCAGGTGGCACTCGGGGTTGTTCGTGGAGATCGCGTTCGCGATGTCCTGCATGATCGTGGTCTTGCCGGCCTTCGGCGGCGAGACGATCAGGGCGCGCTGCCCCTTGCCGACCGGCATGATCAGGTCGATCACGCGGGTGGTGAGCTTGTGCGACTCGGTCTCGAGGCGCAGCCGCTCGTTCGGGTACAGCGGGGTCAGCTTGGTGAAGTCCGGACGGCGCTTGGCCTCGTCGGGCTCCAGGCCGTTGATCGAGTCGACGCGCACCAGCGGGTTGAACTTCTGCCGCTGCTGCTCGCCGTCACGCGGCTGGCGCACGACACCGGTGATGGCGTCACCGCGGCGCAGGCCGTACTTGCGGACCAGCGACAGCGAGACGTACACGTCGTTCGGGCCGGCGAGGTAGCCGGAGGTCCGCACGAACGCGTAGTTGTCGAGCACGTCCAGGATGCCCGCCACGGGCAGCAGGACGTCGTCGTCGCGGATCTCGGTGTCCGGCGAACCGCCCTCGCGCTGGCCGCCACCGCTGCCCCGGCGACGACGGTCGCGGAAGCGACGGCCGCGACGGCCGCCTTCCTCGTCGTCGTCCGGCTGCTGGTTGCGGTTGTCCTGCCCGCCGCGGTTGCCGTCCTGCTGGTTGTTGCGCTGACGGTTGCCGTCCTGGCGGTTGTCGTTCCGGTTGTCGCCGCGGTTGCCACCGCCCTGGCGCTGCTGGTCGCGGTTGCGGTCGCCCTGCTGGCGGTCGCCGCCCTGACCCTGCTGACGGTCACCCTGACCCTGCTGGCGGTCGCCGCCCTGTTGACGGTCGCCCTGGCCCTGCTGACGGTCGCCGCCCTGCTGGGTGTCGGGCGATCCGGCGGCCCGGTTGGACCCGCGGCGACGCCGGCTGCGGCCGCCCTCCTCGGACTGGCCGTCCTGGCCCTGCGGGGTGTCCTGCCGGTCCTGCTGCGGGCGCTCGGCCTGCGGCGGGGCGTCCGACGGCGCGGAGGCGGGCGCCTCGGCCTTCGGCTCCGGCTTGGTCTCCGCCGGAGCGGCGGGCGCCTCGGCCTTCGCCTTCGGGGCCGCCTTCGGCGGCTCGCCGACGCCGTCCAGCGGCAACGTCTCGGCCGCCGCACGCGGCTTGCGGGACTTGCCCTGGCGCTCACGGATCGCGGCGATCAGATCGCCCTTGCGCATGCCCGTCGTCTCGCCGACGCCGAGCTCCCCAGCCAGCGAACGCAGTTCGGCGACGGTCTTTCCGGTCAGCCCGCCGACCGCCCGCTTGGGAGCGGGGGCCGTGCCGTTCGAACCGGCCGTGTCGCTACCCACGTCGCTCAAAAGATCGGTGTTGCTCACACATGTCCTTCCTGACCGATCCACGCCTCCAGGCGGATCAGCGGACTGCCGCTCGCTTCTGATCGCGAACCGGCGTAGTTGCCCCCCGATACGCGAGATGAGCTCTTCGGCCGTGCGGAACACAGCTGGAGCGCCTCCACCACAGGGGTTTGCGTCCTCCATTCGGAGGACACGGAATTCGGCACCGCCGAGACCGGAAACCCGCCTGCGTCCCTCCGCGTTACCCCGCGTGCCAGGCGGTGCGGATTCGGCGGATCGACGAAGGATGCGATCCGGGGGAATCCCCGGGACCGGCATCGGGTGCGGAAACGCACGGTGATCGAACGCCCCCGAGGGTAGACCGCAGCGGTGCCGGGTGCAACAACCACCCCCCGCGTGGCGGGTGTGGCGGCAGGCACGTGACCCACCCTTTACTGAGCCGCAACCTGCACGCCCGCAAGATCCACGGGCAGCTCGAGAACGTCGAAGTCGTCAACGCCGACCCCGGGCGGAAGTATTCCCGTGGTGGTCAGCGCCAGCACCGTCGGACCGGCACCGGAAATCGCGGCGGCCACTCCGTGTGCACGGAGCGTCGCCACCAGCTCCGTGCTCGCCGGGTACGCGGGGGCGCGGTAGCTCTGGTGCAGGCGGTCCTCGGTGGCCGGGAGCAGGAGCGCCGGCTGCGTCGTCAGCGCGTGGACGGCGAGCGCGGCGCGGCCGGCGTTGTGCGCGGCGTCGGCGTGCGGCACGGTCGCCGGCAGCAGGCCGCGCGTGGTGGCGGTGGCCGAGCGGACCGACGGCACGGCCACGACCGGCCGGATCGAGGTGTGCGGCGTGAGCCGTTCGGCGTGGAAGCGCCCGCCGTCGCACCAGGCCAGGACCAGGCCGCCGAGCAGGCTGGCCGCGGCGTTGTCGGCGTGGCCTTCGAACCCGGCGGCCAGCTGCAGCGCTTCGAACGCGTCGAGTTCCCGGCCGGCGAGGGCGTACCCGGCGGCCACCCCGGACACCACCGCGGCCGCGGACGAGCCGAGGCCGCGCGCGTGCGGGATCGCGTTGAAGCAGCGCAGGTGCAGGCCGGGCGGCTCGACGCCGAGGTGCGCGCAGGTCGCGTGGATCGCCCGCACGACCAGGTGCGTCTCGTCGGTGGGGACGTCGGCGACGCCACCGGCGCCGGCGTCCGTCACCTCGACCTTGAGCCCGGCGTCGGTGACCCGCACTTCGACCACGTCGTAGAGGCTCAGCGCCATCCCGAAGGCGTCGAAGCCCGGCCCGAGGTTCGCAGTGGACGCCGGGACGGTGATCCGGAAGCCGGTCACCGCAGGTCCAGCGCCGCCGCGACCGCCGAGGGGTCCACGGCGAGGGGTTCGACCTCGACGTTGCCCGCGAGCGCCGTCTGCGGGTCCTTCAGGCCGTGTCCGGTGACCGTGCAGACGACCCGCGAACCGCGCGGGAGCCTGCCGTCGGCGGCCGTGGCCAGCAGGCCCGCCACGCTGGTGGCCGACGCCGGCTCGACGAAGACGCCTTCGCGGCCGGCCAGCAGCCGGTAGGCCTCGAGGATCTTCTCGTCGGTGACGGCTTCGAAGAGGCCCTCCGACTCGTCCTTGGCCTTCACCGCGGCGGTCCACGACGCCGGGCTGCCGATCCGGATCGCCGTCGCGATCGTGTCCGGGTCGCGCACCGGCTCGCCGTGCACCAGCGGCGCCGCACCGGCCGCCTGGAAGCCGAACATCCGCGGGGTGTTCTTCACCACATCGTCGGCGGCGTACTCCGAATACCCCGCCCAGTAGGCGGTGATGTTCCCGGCGTTGCCGACCGGCAGGCAGTGGATGTCCGGCGCGGTGCCGAGCACGTCGCAGATCTCGAAGGCCGCGGTCTTCTGGCCGGCGATGCGCACCGGGTTGACCGAGTTGACCAGGGTGACCGGGTAGTCGGCCGCGGTCTTGCGGGCCAGCTCGAGGCAGTCGTCGAAGTTGCCGTCGACCTGCAGGATCCGCGCACCGTGCAGGACGGCCTGGGCGAGCTTGCCCATGGCGATCTTGCCCTGCGGCACCAGCACGGCGCAGGTGAGGCCGGCGCGGGCGGCGTAGGCGGCGGCCGAGGCGGAGGTGTTGCCGGTCGACGCGCAGATCACCGCCTTGAGCCCGCTGGCGAGCGCGTGCGTGATGGCCACGGTCATCCCGCGGTCCTTGAACGAGCCGGTCGGGTTGGCCCCCTCGACCTTGAGGTACACCTCGCAGCCGGTCAGCTCGGACAGGTGGTGGGCGGGCAGCAGCGGCGTGTTGCCCTCCCCGAGCGTGACGACTCGCGCCCCGTCCGGGACCGGGACACGATCCCGGTACGCCTCGATGAGTCCGGGCCACGGGTGCCTGATCACTGGTCTTCGCCTTCCACGCGCATCACGCTGACAACTTCGTGTACCACGTCGAGCCGGCCGATCTCGTCCACAGTGGACTGCAATGCCGCGTCGGGTGCCTGGTGCGTCACCACGACCAGGCTCGCGCGGTCGCCGACGTCGCTCTGGCGCACCGCCGCGATGCTGACGCCGTGGTCGGCGAACGCCTGCGCCACCTGGGCGAGCACGCCGGCGCGGTCGGCCACCGACAGGCTGACGTGGTACCGGGTCGGCGTCTGGCCCATCGGCCGCACCGGCAGGGCCGCGTGCGCGGATTCGCGCGGGCCGCGGCCGCCGACGACCCGGTTGCGGGCCACCGCGACGAGGTCGCCGAGCACCGCGCTCGCGGTCGGGGCCCCGCCCGCGCCCTGGCCGTAGAACATCAGCTCGCCGGCCGCGTCGGCCTCGACGTAGACGGCGTTGAACGCGCCGCCGACCCCCGCGAGCTGGTGGCGGCGCGGGATCATCACCGGGTGCACGCGGGCGGACACCGACTCGACGCCGTCATCGTCGGTGACCCGCTCGCAGATGGCCAGCAGCTTCACCGTGCGCCCGAGCCCCCGGGCCGCCGCGAGGTCGGAGGCGGTGACGTCGGCGATGCCCTCGCGGTGCACGTCCGACGCCGTCACGCGGGTGTGGAAGGCGAGGGAAGCGAGGATCGCGGCCTTCGACGCGGCGTCGTAGCCGTCGACGTCGGCGGTCGGATCGGCCTCGGCGTACCCGAGCCGGCTGGCCTCGTCGAGCGTCTCGGCGTAGCCGGCGCCGGTGGAGTCCATCGCCGAGAGGATGTAGTTCGTGGTGCCGTTGACGATGCCCATCACCCGGGTGATCCGGTCGCCCGCGAGGGATTCGCGCAGCGGCCGCAGCAGCGGGATGGCCCCGGCCACCGCGGCCTCGAAGTAGAGGTCGGCGCCCGCGGCGTCGGCCGCCTCGAACAGGTCCGCGGAGTGCTCGGCCAGCAGTGCCTTGTTCGCCGTGACGACCGACTTCCCGGCCTTCAACGCGGCGAGCAGCCAGCCGCGCACCGGCTCGATGCCGCCGACCAGTTCGACAACGACGTCGACGTCGTCACTGGTCACGAGCTTTTCGGCGTCGGCGGTCAGCAGCTCCGGCGGCAGCTCGGGGTGCTTGTCCGGACGGCGGACGGCGATGCCGGCCAGCTCGACCGGCGCGCCCGCCCGCGCGGCCAGCTCCCCCGCCTGCTCGGTGAGCAGCCGGGCGACCTCGCCGCCGACGGTCCCGCAGCCCAGCAGCGCGACCCTGATCGGACGTCGGTCGGCTGCAGGCAGTTCGGAAGCAGACACGGTGTTTCAGACCTCCAGGCGCAGCATGTCGTCGGTCGTCTCCCGCCGCAGCAGCAGCCGTGAGCTGCCGTTGCGCACGGCGACCACGGCCGGGCGGGGCATCCGGTTGTACGTGCTCGCCATCGAGTAGCAGTACGCGCCGGTCGCCGCGACCGCCAGCAGGTCGCCGGGAGCCAGCGTGTCGGGCAGCCAGCAGTCTCGTACGACGATGTCGCCGGACTCACAGTGTTTTCCCACGACCCGGGACAACACGGCCGGTACCGGCTGTTCGTTGTCGCCCGCGGAGCGGGAAACCAGCCGGACGTCGTAGACCGCGTCGTAGAGCGCGGTGCGGATGTTGTCACTCATCCCGCCGTCGACGCTGACGTACCGCCGCGCCGACTCGTCGCCGAGCGAGACGTCCTTGATGGTGCCGACCTCGTAGAGCGTGATCGTGCCCGGACCGGCGATCGCGCGGCCCGGCTCACCGGCGATCCGCGGCACCGGCAAGCCCGCGTAGGCGCACTCCTTGCGGACGATCTCGCGGATCTGCGTGATCATCTGCGCGGGCGGCGGCGGGTTGTCCTTCTCGGTGTAGGCGATGCCGAAGCCGCCGCCGAGGTCGACCAGGCTCAGCTGGTCGAGCAGCTCGGGGCCGTGTTCCTTGGCCAGGTCGGCGAGCAGCCCGACGACGCGGCGGGCGGCGACCTCGAAGCCGTCGGCGTCGAAGATCTGCGAGCCGATGTGGCTGTGCAGGCCGACGAGCTTGAGCGAACGCGCGTTGAGCACCCGGCGGACCGCCTCGGCGGCGTCGCCGCTCGCCAGCGAGAACCCGAACTTCTGGTCCTCGTGGGCGGTCGCGATGAACTCGTGGGTGTGCGCCTCGACGCCGACGGTCACCCGGATCAGCACGGACTGCACGACGTCGTGGCGGGCGGCGATGTCGGCCAGCCGGGCGATCTCGAAGTACGAGTCGAGCACCACCGTGCCGACCCCGGCGACGACCGCGGCTTCCAGCTCGGCGGGCGACTTGTTGTTGCCGTGGAAGGTGATCCGCTCGGCCGGGAAGTCGGCGCGCTGCGCCACGGCGAGCTCGCCGCCGCTGCAGACGTCCAGGCTCAGCCCCTGCTCGGCCACCCAGCGGGCGATCTCGATGGACAGGAACGCCTTCGACGCGTAGTGCACCAGCGACGGGTCGTCGAAGGCCTCGGCGTAGTCCGCGCACCGGGACTTGAAGTCGGCTTCGTCGACCACGAACAGCGGCGTGCCGTGCTGCTCGGCGAGCTCGCGGACGTCGACGCCGGCGATCCGGACGACACCGTCGGCGGCGCGGAAGGTGTTGCGCGGCCACACTTTCGCGGGCAGCTTGTCGAGCTCCTCGACCCCGGACGGCTGGTGCCCGGAAGTGTCGGCGTGGGTGTAGACGTCGGCGTGCCTGGGGCCCGCGGGGTGCGCCATTTCTTACATCCGTTCCGGAGCGGAGACACCGACCAGCGCGAGACCGTTGGCGAGCACCACGCGCGCCGCCTCGCAAAGAGCCACCCGGGCGTGGTTGGCGGGGGTGGCCGCCTCGTCGCCCTTGGGCAGCACGCGGGCCTCGCGGACCGCGTAGAACTTGTGGAGCGCGCCCGCGAGCTCCTCCAGGTAGCGCGCGATCCGGTGCGGCTCCCGCATTTCGGCCGCGCGGCGCACGGTCTCCGGGAACTCGCCGATCGTGCGGATCAGGTCGCCCTCGACCGGCAGTGTCAGCTGACCCAAGTCGACGTCCTCCGTGGACTTGAGACCGAGGTCCGCCGCCCCGCGCAGCATCGTGCACAGGCGCGCGTGGGCGTACTGGACGTAGTAGACGGGGTTGTCGTTGGAGTGCTTGCGCAGCAGATCCAGGTCGACGTCCAAAGTGGAGTCGACGGAGTAGCGGATCAGCTCGTAGCGGGCCGGGTCGACGCCGACGGCCTCGACGAGGTCCTCCATGGTGATCACGGTGCCTGCGCGCTTGGACATCCGGACCGGCTTGCCGTCGCTGACCAGGTTGACCATCTGGCCGATCAGCACCTCGACCGTGGCGGGGTCGTCGCCGAAGGCCGCCGCGGCCGCCTTGAGCCGCGCGGTGTAGCCGTGGTGGTCCGCGCCGAGCATGTAGATGCACAGGTCGAAGCCGCGGTTGCGCTTGTCCTTGAAGTAGGCCAGGTCACCGGCGATGTAGGCCGGGTTGCCGTCCTGCTTGATGACGACGCGGTCCTTGTCGTCGCCGTACTCCGACGACTTCAGCCACCAGGCGCCTTCGTCGAAGTACAGGTTCCCGGAGTCCTTCAGCTGCTGGACGGCGGCGTCGACCGCGCCGGACTCGTGCAGCGAGTTCTCGTGGAAGTAGACGTCGAAGTCGGTGCCGAAGTCGTGCAGGCTCTGCTTGATCTCGGAGAACATCAGGTTGATGCCGATCCGGCGGAACGTCTCGTGCCGCTCGGCCTCCGGCAGCGACAGCGCGCTCGGCTCGGCCTTGATGACCTCGGCGGCGATGTCGTTGATGTAGCCGCCCGCGTAGCCGTCTTCCGGCGCGGGCTCGCCCTTCGCGGCCGCGATCAGGGACCGGACGAACCGGTCGATCTGGGCGCCGGCGTCGTTGAAGTAGTACTCGCGGGTGACGTCGGCGCCCTGCGCGGCCAGCACCCGGCCCAGCGCGTCGCCGACCGCGGCCCAGCGGGTGCCGCCGAGGTGGATCGGGCCGGTCGGGTTGGCCGAGACGAACTCGAGGTTGATCCGCGTGCCGGCCAGCGCGTCGCCGCGCCCGTAGGCCGCGCCGGCGTCGAGCACCTGGCGCACGATGTCGCCCTGCGCGGCGGCGGCGAGGCGGAAGTTGAGGAAGCCGGGGCCGGCGACCTCGGCCGAGGCGACGCCGTCGTCCGCCGAGACCGCCGCCGCGAGCGCCTCGGCGAAGTCACGCGGCTTGAGGCCGGCCTTCTTGGCCACCTGGAGGGCGAGGTTCGTCGCGTAGTCGCCGTGGTCGGGGTTGCGCGGGCGTTCGATGGTCACCTGCTCCGGCAGCACGGCGTCGTCGATGCCGCGTGCGGCGAGCACCTGCACGGCGGAGCTGCGGACCAGGTCGGCGAGAGCGGCGGGAGTCACTTGCCGAATTCTAGGTGTGCCCAGGTCGGGCGGTTGCATCGGTCTCGGCCACGTCACGGCAGGTGGGTGTGTGAGGCGTTAACGGTAGTCAGACGCGTGGTCTCTACACTGGCCCGGGCGGGAATCCGTCCGCAGCCACCAGAGGGAGAACGCGGGAGCCATGGCGAACGGGACAACTCGGAAAAAGGGGTCGGCGGTGAAGGCGGCCCGTGGTTCCGTGGTGAGCAAGAAGGGCACCCCGTGGGGCACGATCATCGCCGTCGTCGCCATCGTGGCGCTGGCCGCCTCGGTGATCATCTACTACATGGTGCAGTCCGCGCCGAAGCGTGCCCAGGCCGACCGTGAGGCCGCCGCCGCGTCGTTCGCGCCGACCGCGTCCGAGCCGGACCCCTCGAAGCGCATTCCCGGCGTGGTGACCGCGACCTACACCGGCAGTGTCCACGTGCTCCCGACCGAGCGCGTCGCCTACGACAAGACCCCGCCGTTCGGCGGCCCGCACGACCAGACGTGGGCCACCTGCACCGGCATCGTGTACCCGACCGCCGTCCGCACCGAGAACATGGTGCACGCGCTCGAGCACGGCGCCGTCTGGATCGCCTACAACCCGCAGCAGATCACGGGTGACGCGCTCAACATGCTGAGCGTCCGCGCCAAGGGCAAGCCGTACACGATGCTGTCGCCCTACCCGGGCCTGGACAAGCCGATCTCGCTGCAGTCGTGGGGCCACCAGCTCAAGGTGGACGACGCCAACGACGCGCGCATCGACGAGTTCATCGCGGCGCTGCGGAGCAACCCGAACGGCGTCTACCCCGAGGTCGGCGCGTCCTGCGACGCGGTTCCGGGCCAGTTCGACCCGGACAACCCGCCGCCGTTCAACCCGGCGAAGCCGGGCCCCGACGCGAAGCCGATGGACTACAAGGGCAGCACCGCCGCGCAGGGTGAGCAGGGCATGCCGCAGTCCGCGCCGGCGTCCGCCCCCGCTTCGGCGCCCGCTTCCGCCCCGACGACGAAGTGACCACCGAAGCCGGCCTCGACACCGATGAGGTCACCGAGCAGCCGACCTGGTCGCGCTGGGTGATCATCGGCGGGACGCTCCTCGCGGTCCTGCTGATCGGCGCGACGGCGGGGATGTTCTTCACCCGCGCCGTCGACGACCCGGCCACGGCCACCCCGGCCGCCGGTTCGGTCGAGGTCGGCTTCGCCCAGGACATGTCGACGCACCACCTCCAGGCGGTGACGATGGCGGGTATCGCCCGCGACCGCACGACCGACCCGGAGATCAAGCAGCTGTCGTTCGACATCGAACGCACGCAGCTCGAACAGGTCGGCCGCATGAAGGGCTGGCTCATGCTGTGGGACCAGCCCGAGCAGCCGATCGGCGCGCCGATGCAGTGGATGACGGAAACGATGACGGGCCACGACGGGATGTCGATGGCCCCATCCTCGGTCAACCCGGCGGAAGGCCCGCTGATGCCGGGCATGGCGACGGACACGGATCTGAAGAAACTGCGCTCGCTTTCGGGCCGCGAATTCGACGTGTATTTCCTCCAGCTGATGTTGCGCCACCACCAAGGCGGGACGTCAATGGCCCAGTACGCGGCGGCGCATTCCACGCTGCCGGCGTTGAAGGCGCTGGTGAACAGCATCTTGACGTCCCAGGGCGCGGAGATGGACCAGATCAAGCTGATGCTTTCCGGCCGGGGCGCCCAGCCACTGCCGGCCTAGCCGTCAGAACTCGAGGTTCATCGTGTTGCCGTCGCCGATCTGCACGCCCTTCGAGTCGGTCACCGTGACGTGGTACTTGCCCGCCCGGGCGCCCTCTGGGTCCGCCTCGCGCAGCACGGCCCGCGCGGCTTCGAGCACCGCGGCGTCGTCTCCCACGTTCGCCGCGGCCAGCTCCGCCGCCAGCTCCTCGGGGTCGTCCGGCAGCCGGCCGATGAGGCGCCGTACGCCGGACTTCAAGCCGTCGTAGGCTTTCTTCACCGCGTCCGTCGCCGTTTCCTTCGCTGCCGCCGCCGCGCCCGCCGCCAACGCGGTCATCACCAGTTCCACAGCCTCGATCGCCACTGCACGCTCCCGGAGTCGAGCCGCCGTCTCCGGACAGTCTCCCGGAGCGGGGCCGCCGTTACAGCGTCACCAGGAGAGTTCTTGGCAGCGGCGGGCGCACTGCGGCGCCTCCACCTGCAGCGTCGCGTGCTCGATCGCGTACCGCGAAGACAGCAGGTTCTGCGCCTCCGTCAGCACGTCCGACTGCTTCGCCGGCGGCGCCAGCGTCAGGTGCGCCGAAGCCACCTCCATGCCGGACGTCAACGTCCAGACGTGCAGGTCGTGCACGTCCGCCACGCCCGGGAGGGCCGCCAGCTCCGCGTTGATCGCGCCGACGTCGACGCCCTGGGGCGCGTGCTGGAACAGGATGCGCAGCGCCCGGCGGGCCAGCGTCCACGTGCGGGGCAGCACGAACAGCCCGATCGCGACACCGATGATCGGGTCGGCGTAGCGCCAGCCCGTCAGCAGCGTCACCGCGCCGCTGATCAGGACGCCGACCGAGCCGATCAGGTCGGCCAGCACTTCGAGGTACGCGCCGCGGACGTTGAGGCTCTCCTTCGCCCCCGACCGCAGCACGGCGAACGACACCAGGTTGGCCACCAGGCCGGCCACCGCGACCAGCAGCACCGGCAGGCCCGGCACCGCCGGTGGCTCGCCGATGCGGCCGACGGCCTCGATCAGGACGTACCCCGCGACGCCGAACAGCAGCAGCGCGTTGGCCAGCGCGGCCAGCACCTCCGCGCGGTAGAGCCCGAAAGTGCGGCTGACCGTGGGCCCGCTGCGCCGCGCCAGGATGATCGCGGCCAGCGCCATGCCGACCCCGAGGACGTCGGTGAACATGTGGGCGGCGTCCGAGAGCAGGGCCAGCGAGCCGGTCGTCACGCTGACGACGAACTCGAGCACCATGAACCCGGCGCCGATGCCCAGGGCGATGGCCAGCCGTCGCACGTAGCGCCCCGACGCGCTCGCCGGCGCGATCGCGTGCCCGTGGCCGTGTCCCTGACCCATGCCGCCTCCGTTCCCGGTTCGCCGTCGGGTCAAACATATAGTCGGATGCGCATATGTGCAACAGAGGCCAGCCCAGGGTCATTCACGGGCAAGCTACCGCGCGCGGCCGGGCCACCCAATCCACCAGGCGGGGTTTCCCGCCAGGCGGACTCGTCACGCTTCGGCGTCGACCATCCGGGCGAGCAGGTCCCGCAACCGGACGCGGTCCGCCGGTACGAGCGCGGCCAGCGGTTCGGCCGCGAAGCCCAGCGCCCGCCGGAAGTTCCGCGCCAGCTCGGCCCCCGCCGGCGTGGCCACGATGTTCTTGATCCGCCGGTCCCGTTCACCCGGTCGACGCTCCACCAGCCCGCGGGCCTCGAGCCGGTCGATGATCCCGGTCACGTTGGACCGCTCGGACTTCAGCTTCTCGGCGATCCGGTGCATGGGCAGTGGTTCGTCGAGCGCGACGAGCACCTTCGCCTGCACCGTCGTCAGTCCCTGCGCCGCCGCCGCGGCCTCGTACGACTCGACGAACCGGTCGACGATCCGCCCGAGCAGGGCGACGACGTCTTCGGTGATCGGGTCAGCGCTCATCAGCCGAGTGTATGCCGATAGTTGACTGCATGAACCATCCATGCCTATAGTCATTTTAGTTCACTACCTTAACCATCACTCCCCTGAACAGATCGAGGTTCGTCAGATGAGCAACGACCGCGTCGCCCTGATCACCGGCACGTCCTCCGGAATCGGACTGGCCACGGCGGTACTGGCGGCCCGGCGAGGCTTTCGCACGGTCGCGACGCTGCGCGACACCGGCCGCGCCGACCGCCTGCGCGAGGCCGCCGCCGACGCCGGCGTCGAACTGGACGTCCGCCCGCTCGACGTCACCGACGCCCACTCCGTCAGCGCGGCGGTCGCCGGTGTCCTCGCCGACTACGGCCGGCTCGACGTCCTGGTCAACAACGCCGGCGCCGGTCACATCGGCACGATCGAGCAGGAGCCCGTCTCGGCGGTTCGCGAGACGATGGAGGTCAACTTCTTCGGCGTCGCCGAGACGACCAAGGCCGCGATGCCGGCCCTGCGCGCCAGCGGTGGCCGCCTGATCACGGTGACCAGCGTCGGCGGCGTGATCGGCCAGCCGTTCAACGAGGCCTACTGCGCGGCGAAGTTCGCCGTCGAAGGCATGATGGAAGCCCTGGCGCCGGTCGCCGCGGCGCAAGGTGTCACGGTGTGCGTCATCGAGCCGGGTGCGGTCGCGACGGAGTTCGTCAACAACGTCGGCGTCGACGAGCGGCTCTTCGCCGAGGCCGGTCCGTACGCCGAGTCCCTGCAGAAGTACATCGCCAACGTCACGCAGTCGTTCCAGAGCGCCCAGACCGCCGACGAGGTCGCCGAAGTGATCCTGGGCGCGATGACGGCGGACGCGCCCGCCTTCCGCATCCAGACGTCGAAGTGGGCCGAGGAGTTCGCGGCGCTCAAGTTCGCCGACCTGGACGGCTCGGCCGTGCAGCGGCTGACCGGCGGCTGGCTCGCCTAACGCACCAGCCGGAAGAACCCGCGCACCTGCTCGACGAACAACCCGGGCTGCTCCAGCGCGGCGAAGTGCCCACCGACGGGCAGCTGCTCGAACCAGCGCAGGTCGGTGTAGCGCTGCTCGGCCTGCCGCCGCGACGGCCGCACGATTTCCTTCGGGAACACCGAAACCCCGGCCGGAACGTCCACCGTGGACAGATCACGGTCGTTGTTCGCCCAGTACATCCGCGCGGACGAGGCCGCCGTCGCGGTGAACCAGTAGACGGAGATCGCGTCCAGGATGCTTTGCCGGTCGACGGCGTCCTCCGGCCGGCCCTTGTTGTCGGTCCAGGCCCAGAACTTCTCGGCGATCCAGGCGGCCTGGCCCGCGGGCGAGTCGGTGAGGGCGTAGCCGAGCGTCTGCGGGCGGGTGCCCTGCTGGGCGGAGTAGCCGCTGCCGCTGCGCCGGAACTCCTCGAGATCGGCGAGGGCCCGGCGCTCCTCGGGCGTCGGATCGGCGGTGTCCATCCGCACGGGCGCGAAGTTGACGTGCACGCCGGCAACGTGGCCGGACCGCGCCACAGCGTTGGTGACGGCGGCACCCCAATCGCCGCCCTGGGCGCCGTAGCGGTCGTAGCCGAGCGACGTCATGAGCCCGTCCCACAGCTCGGCCACCCGCCCGATCTTCAGCGCGGGCTTGTCACTCCACCCGAACCCGGGCAGCGACGGCGCGACGACGTGGAAGGCATCGGCGGGATCGCCCCCGTGCTTCGCGGGATCGGTGAGCGGCCCGATGACGTCGAGGAATTCGAGCACGGACCCGGGCCAGCCGTGGGTCAGCACGAGCGGCAGCGCCTCGGCCACCGGCGACCGGACGTGCAGGAAGTGCAGGCCGACCCCGTCGACGGTGGTCCGGAACTGGGGGAAGGCATTGAGCCGGCGGGCGAACCCGAAGTCGTATTCCTCGCCCCAGTCCCGGCAGAGCTCGCGCACATAGGCGAGCGGAACACCCTGCGACCAGTCATCGACGGTCTCGGCCTCGGGCCACCGAGTCCGCCGCAGCCGCTCCCGCAGATCGGCGACATCGGCCTCATCGAGAGCTACCTGGAACGACTCGGCCATTTCGGCTCCTTCAGGTGGGCCTCCCACGCTAGCGACGACCCGCCGAACCGATCAACTTCACGGCGTTGACCAGGGAGGTTGCCGGTCCGGCCACCTGCGGGAGGTGGGTCGCGGGGCATGCGCTAAGCTTTCGAAGTCGCCCAGCGATGGGCCCTCGTAGCTCAGGGGATAGAGCACTGCCCTCCGGAGGCAGGTGTCGCAGGTTCGAATCCTGCCGAGGGCACTCTCTTTGATCACGCAAAACCGGCCCCTACCAGCGAGAACGCGGTAGGGGCCGATCTGTGTCTTACCCGGCGGACCACGGCGGACTGCGGCCGAATCCGGGGGCCAGCGGCCAATGTACGGCCAAACGCTCACCGGCCCGAGCCGAGCGCCGTCTCCACCTGCCGCCGCGCGGCCTGCTCACCGCCGTCGAGGAAGCTGGCGTAGATCTCCAGCAGCACCGAGACCGAGTGGCCAGCCCACGCAGCGACCGTCGCGGGGTCAACGCCCGCGGCCAGCTGGGTGCTGACGGCCGCGCGCCGAAGGTCGTACGGACGCCCGGCAAGCGGCGTCGCGCGGACCTGCTCGGTTAGCACGGCCTTGCGAGCGGCACGCCAGGCGCGGGTGTAGGTAATCATCGGGATCTCGCCCCCCTGCTCAGCCTGGAACAGTCGGCCATCCGGCCCATACCCGAACTGCCGCACATGCCGCCAGAGCAACCGAGTCAAGTCCGGCGGGAACGCCACGGTGCGTTCCTCGTCGTCGTCCCGGGACTTGAGCGGCCGGTCGTCGCGGGTTTTCCCACTGTCCGTCCAGCGGCCACCGACGTGCGGCTCCGCCTTGTCGAGACGGAACCCGCCCCAGTCGTACTCGAACTCGTTCGCGTCCCCGTTCCACACCGGCTCGGGGAAGGACGCCAGGTTTCGCTTGTTCAGCGACACGGCTTCCTCCGGCCGCAGGCCGGCGTAGTACATGGTGCCGAAGAACGCTTCCAGCCGTGGCCCGCTGCGTGGCAGCGCGCCGACGCCGGCCAGCAACGTGCGGGCCTGGATGGGGTTCGGAACCGCCCGCTTGTCAACCTTGCGTTTGCCCTTCGGCATCGCCGTCCACTTCACCGACGCCAGCGGGTTCGCCTCGATCAGCCTCTTTCGATGGCGAACTCGAGCGCGTTGAACAGCACGCTCCTTACCCTTGCCTGCACCTTACAACGTATGGTTACCTTACATGGTAAGGCGTGAGGGGGTCTCGCATGAAAGCTGCGGTGCACACCAGGTACGGCCCGCCGGAGGTCGTTCGGATCCGCGAGGTGGACAGGCCGGCGATCGGGGACCGGGACGTGCTCGTCCGGGTGCACGCGACGACGGTGAACCGGACGGACTGTGCCTACCGGGCGGCGAGGCCCCTCTTCATGCGACTGCTCACGGGCATCGCCCGGCCTCGGCGGACGATCATGGGAACCGAGTTCGCCGGACAGGTCGAGGCAGTCGGCCGTGGTGTCATGTCCTTCTCGGTAGGCGACCAGGTGTTCGGGTACAACGAGGGCGCGTTCGGCGCGCACGCCGAGTACCTGTCGGTGCCGGAGGACGGATCGATCGCGACCATGCCGGCGGGCGTGACCTTCGAGCAGGCCGCTCCCGGTACCGAGGGGGCGCACTACGCGCTCGCGTGTATCAGGCATGCGGGGACCCGGGCCGGACAGGACGTCCTCGTCTACGGCGCGACCGGCGGGATCGGCTCGGCAGCCGTGCAGTTGCTGAAGAGTCTCGACGTCACTGTGACCGCGGTGTGCGCCACGGAGAGCCTGGCGCTGGTGAAACGCCTGGGCGCGGACCGGGTCGTCGACTACACGGTAGGGGACTTCACCGAGGACGAGCAGACCTACGACGCGGTGTTCGACGCGGTGGGCAAGAGCACGTTCGGCCACTGCAGACGACTGCTCAAACCCGGCGGGGTATACCTGTCCTCCGAGTTGGGGCCCTGGGCTCAGAACCTCATGCTGGCATTGGTCACCCCGCTGCTGCGCGGGAGGAAGGTGAAGTTCCCGTTCCCGCGGGACAACCAGGCCATCGTTCGCCACCTGCGAGAGTTGATCGAGTCCGGGGACTTCACGCCGGTCATCGACCGTCGGTATGCCCTGGACCAGATCGTCGATGCCTACCGGTATGTGGAGGCCGGACAGAAAATCGGCAACGTCGTGATCACCGTCACGGACGTGGACTGACCGATGGCGTTGCGGGACAGCCCTTTCAGTCTCTGGCAGGCTGCTGTGCTGCGATTGTCTCCAATTGGCGTACGCCGTCTTCTGCCTGGATCAGGTGACCGAGCCGGTTGGCACAGGCAGTGACCCCAGAAGGATTGGTCGGCAGCACCGCCGCCGTGGCACCGTGGTGGATCACGGCGGCGCGACGTAACTGTTCAGGCCATTTCGATTGTTGTTGGTAGCCAGGGGTTTCCGGTGATGGCGTCGCGGAGTGCGGCGATGATGTGGAGTCCGTTTTTGCGGGCGGTGGAGATGTAGCCGCGGACGCGTAGCCAGGCGTGGGCGCCGTGCCGGGTTCGCCAGCCACCGGAGATCTTCAGCTGGGCTTTGATCATGCGTGGTCGCCTCGGCCGGGCCGGTTGCAGTCGTGACCTGGCGGCAACCTCCGCACCGCAGCCGGTGCAGGCGGTGCTCGGTCACCGACGGACGCACCGGTGGCAGGTCCACGACTTGGCGGCGGATCACCCCGGCACGGTCGGTGCGGCGCAGACCCCCGCCGCATCCCGAGCACGCCGACGATGCGTGGTCGACGACCATGTCCGGATTTTCGACCAATGACAAGTTCGCTCCGGGCGTGCCGGGCTGCTTGCCCGGTTTGCGTCCGGTCTTGCCGCGCAGCGACTTGGGGGCGGGTTTGCTGAACCGGTCGCCGTTGCCCAGGCCATCTCAGCAATCAGCCTCGCCCTCGACGACCCCCGACTTTCCCGCCGAAATCTTCCGATGACCCCCACCCGGGCCAGTAACCCGATCGGCCGCGGTAGACAGCGAACTCGTCGCGAAACCAGCGCCACGCGATGACCATCACGTGAAGCTTCGCGTCGACGTGATCGAGCCGTTCGCGGCTGCGGTCGGCGCGAACGAGCTCCGGCTCAGCCGCGTGGTCCCTGGACCAAACCGGTTCTTCCGTCCACCTGCCCTTGAACTCGCCCATCGCGCGGACGTTCTCGGGCCCACGCCGGGCTGGCCGTGGTCTCCTTGCTCGCTCGGTTATCGCCTGCTGGGACGTCGAAGCCACCGCACCACGCTTCGACAGCTCGCGCAGGCATGACAGACATCAGTCAGAGACTACGTCCAGGCGGGATCACGGCCGGTCAGGCCGATGATGCGGTCCAAGGTGGGTGCGTCGGCCGGCACCGCGACCTCCGGTCCGTACATGCCCATTTCTCGTCCCTGCTCCACGCCGGCGACCACCGTGTCGTGCAGGTGCGCCAGCAGGTCGGCGGGCAGTTCCAGCCGCTGCCCGGTCGCGACCGCCAGATCCCAGCCGTGCACGGCCAGCTCGCCGACGATCATGTCTCCCATGACGGGCGCGGGCAGCGTGTGCGGCGTGCCCATGCTCGTCTCGCCCTCCCAGGCGCTCGGCTGCGCCCACGACGACGTGATGTCGTCCAGCAGGGCGAGCAGGCGGCCGCGCCAGTCGCCGGCCGCCAAGTCCACATCGGACTCGGCGGCCGCCGGCTGCGGAACGGACTCCTTGCGGCCAGCGCCGGCGAGCGACGGGCCCCAGAACAGGAGGTGGTTGACCAATGCCCGCACGTCGTACTCCGTACACGGAGTCTTGTTGGCGAGCTGGTCATCGGTGATGGTGCGGGCGGCCGCGGCCATGGCCTCGGCCGCGTTGGATACATGTGACATGACGGCCACGCTAGGCGGCGCCGGCCGGAGGGGTATTGAACAAAGACGACGTACACTTTGCTGTGTGGGGCGGGACGTTCGTGAGCTGCGGGGTGCGTGGACCAGGTATCAGCGCCACGCGTTCCACCACCCGTCGCCGGCGCTCGCGCCATGGGTGGAGCGGTACTGGGAGGCTCGCTGGGACTACGCCGAGCCCTACCGGCAGAAGATCGTGCCGTACCCGAACGTGCACCTGTCGTTCAGCGGCGGCCGCGCGGACGTCAACGGTGTCCGCAGCGGCTACCAGCTCAAGGTCCTCGAGGGCCGCGACCACGTCTTCGGCGTCGCGTTCCGGCCGGGCTGCTTCCGCCCGTTCCTCGGTGCCTCCGTCTCGACGATCACCGACCGCGTCATCCCGGTGACCGCGGTGTTCGGCCCGGACCTGCCCACGACGCTCGACGTGCCGACCGTGGATGCGTTCCTGTTGAAACACCTGCCGGACGACGACCCTCGCGTGCGCCAGGCGGTGGCCGCGGTCGAGCTGATCGCCAACGACAAGGCCATGACCAGGGTCGAACGCCTCGCCGACGAGCTGGGCCTGAGCATGCGGGGGCTACAACGGCTGTTCGCGGAGCACGTCGGCATCGGGCCCAAGTGGGTGATCCGCCGCTACCGCCTGCACGAGGTGACCGCCCGCATGGCCGCCGGCGGGGCGATCGACTGGGCCGCACTGGCGGCAGACCTCGGCTACGCCGACCAGGGCCACTTCATCCGCGACTTCAAGAGCATGTTCGGCGAGCCACCGACCTGGTACGCACAGCGGTATTAGTCCGCCCCGGCGACCTGACCGGCCTGGTCGCCCGACCCCGGCAACGAGTCTCTACCGAACCCGGGGCGGTTCAGCTTGGTCAGCCGGTCCGGATCCACCGGCCGGTCCCCACAGCCCCGAATCTCGATGTTCGACGAATACGGCGAAGGCAACCAGATCGCGAAGACCGCGGAAAACGCCTCCATGACACCCGTCGGCTCCGGCCTGCTCGCCCTCGACGAAGACGGGACGGCCTGCTCGTCGGACCACTACCTGCGCCTGACCGCCGACGGCGGCCGCATGCGCGAACAACGCGTTTCCCCAGTGGCTCCAGGTCGATCTCGGCGCGGCGACGGCAGTAACGCGGATCGTGCCGGCGGTGCCACCGTCGAGTGCGTGGGCCGCCCGCACGCAGACCCTGGCCGTGTCCGGCTCCTCCGACGGCACCACGTTCGACACCCTGGCTCCCGCGACGGCCTACCCGTTCGATCCAGCGCGAGGCGACCTTGCGCGGCGAGTTCCCTGGTTCGCGCGGCCTCGCGTCGTTTGGTGTCCTCCGGTGGTGCCTTCGGGCACGGTGGTCACCATGTCGACAAGAAATTCCATGATCGTGTTTCCCGTTCAGTCGAGTCGGGAGACCTGATAGTGGCTGATGAGCCAGGTGTCGCCGGTGCGGCGCAGGATGACGCCGAGATACACCGGCAGCACCGGCCGGTCGGTGAAGCCGAAGTCGACGCTGAGGTAGCCGAGGACCAGATCGTCGGCGAGAACCCGGATTTGCAAGACGGTGTAGTCAGCGGTCATGCCGATGGGCTGGCCGTGGTAGTACGCAGCCACGCTGTCCGGGCCGACGCTGTCCGGGTGCAGGCCTTGGAAGATCGCGTCGCCGGTGAAGCAGGTCGCGACGCGCTTCGGGTCGTGCGCGTCGACCGCGGACTTCCACCGGTCGAGCACGGTCGTGAGGATGTCGGTCTCAGTGCTTGTCATGACGAATCTTCTTTGTCTGTGACAGATTTGTCGTCGGCGTGCCCAGGTCGTGCGGGAACCGCTGCCGTAGCGCGGCTGCGGCGACCGCCGCCAGTGCGACCACGCCGGCGCCGACCAGCAACGCCACGTGGTAACCGTTGCGCAGCAACGGGGTCACGACCGCCGGGCCGAGGATTTGCCCGGCGCTCGGCCCGGTGTGCCGGCATGGGCAGCCACCAGGCGAGGATCGCGCACACCACGGTCAGCCCGGCCGCGCTCCACCACGCCTGCTGCCAGGTACCGGTGGTGTGCAGGACGAGCACCAGGCCGCCGGAGAGCGCGATCCCCGCTCCGACGCCGCCGAAGCCCCAGCCGACGAGATGCTGCGCGCGAGCGCGCAGTCCCGCGAGCAGTGCGCTCACGGCGATGACGAAGATCAACGCGCCGACGGCTGATGCGGCCACACCAGCCGCTGCGGCGCCGCCCGGTCCGGCCGCGGCGCCACCTCGTCGATCAGCAGGTCGGTTGCAAGCCTGGCGTCGCCTGGCCATGTCGATCTCGCCGACAGCCGCGACGATCACAACTTCGGGTTCCTCGATGGCTGAAACCGCGAGGAGGGCGAGCGTCTCCGGCTCGGCTGTCTGCGCGCCGTGAGGTTCACCCCGGGTAGTGGACACCGAGTTAGCAGGACCAGGGGTTCTGCTGGAAGGATGTCCTCATGCCTCCTCGCAAGCGCCGGTCGTACCCGGCGGAGTACAAGGTCGAGGCTGCTCACCGCGTGATCGATTCCGGCCGGACGATCGCGGAGGTCGCCCGCGAGCTGGGTCTCGACGCGGGCATGCTGAGTGTCTGGGTCAAGGACGAGCGGCGCCGGGTGACCGCGGCCGAGGTGCACGGCGAGAACCCTCTGGAGGCGGCCGAGCGGGCCGAGCTGCTGCGGCTGCGCGGGCAGGTGGCCGAGCTGGAGAAGGACAACGCGTTCCTGGTAAAAGCCTCGGCGTACTTTGCCGCGATGCAGAAGAACCGGCCCGGTTCGCTCTGATGGCCAAGTACGCCGGCCCCGACGAGTCCGCCGACACTGCCGGCAGGGTCCCACTTCGGAACGAACGTCGGTTCTCGGTCCGGCGCATGGCGCGACTGCTGAATGTGTCGAGGTCCGGCTACTACGCACACGCCACACGCGCCGCCGCAACGGTCCTGGCGCCGCGCCGGCAACGCCGGGCCGACCTGGAGGTGAAGATCACCCAGGCGCACCAGGACTCCGGTGGCACTTACGGGTCGCCGCGTATCACCGCGGAACTTCGCGACCAGGGCGAGGTGGTCACGGCGAAGACGGTTGCCAAGATCATGGCCGGGGTGGGGCTGGAGGGCATCAGTCCGCGCACGTTCAAGGTGCGCACGACGGTGGTCGATCCGGCCGCGTCGTTCCCGCCGGACCTGGTCGGCCGGCACTTCGACCGGGGCCGGACCGACGCGGTCTGGCTGACCGACATCACGTATCTGACGTGTGGTGAGGGCGACATGTTCCTGTGTGCGATTCGGGACGGTCATTCCCGGAAAGTGCTGGGCTACAGCGTTTCTGACCACATCAGCGCCGAGATGGTCACTGCCGCCATCGACGACGCGGTGGCCGGCCGGGGCAGCGGGTGCCGCGGCACGATTCTGCATTCGGACCGCGGCGGCGAGTTCACGGCGAACGTGACGGCGCAGGCATGCTTCGGTCACGGGCTGCGCCGGTCGATGGGCGAGACCGGGATCTGCTGGGACAACAGCCCGGCGGAATCATTCTGGTCGACGTTCAAACATGAGGAATACTACCGGCACGTCTACGCGACGAAAACGGAACTCGTTGCCGCGATTGACAAATGGCTGAATTTCTACAACAGTAGGCGGCGCCACTCCTCGATCGGGATGCTCAGCCCCAACGACTACGAGAAGTCGCTGCCAGTGGTTGCTTGAACTGTGTAAGCCCCTGTCCACCGTTCGGGGTGAACCTCACCGGGTGCGGGCCAGCCAGTAGATCGGCAGCTTCAGCATCTCTCGCCCAGCGCCTTGTCGAAGGGGGCAACATCGGCCTCGGCGATCGCAAGCCCGCGACTGCTCCACACCCGCGGCGCCCAGTACCCACTGGAGGAAGCATGGGTGAAGCGCGCGGTGATCGTCCAGTCAGCCACGGCGGTGAGGGTCGGCACGACGACTCCCTGCGGTCGCGGCCCTCAGGTTCGCCACACCGTAGTGGATCATGTCCGGACAGTGGTACCACCGGCGGCACATGGGTGGTGCGCCGACCGGCCGGTCGTGGCGCCGAAGACCGAGGTCAGCGGCACGCTTGCGGAAGCCAGACTAGACGTTGTTAACCTGAGATTCACCTATCGATCACCAGATGAGGGTAACCATGCGAGGTTGGCAGACGTGCACAACGAACAGCCGGTAGAGCTCGCTCCACGGTCGGTGGCCCAGCTCACCCAGGACCCAGCCTGGACGGTCACCCGCACCGGCACGACCGGGCAATGGCTCACCGCCGAGCGGGTCCTCGAGCGAAACGGGCACCGTCGGCTCGTCGGACTGACGCCCATCCAGCCCGGCGTCGTCGCCCTCATACTCTGGGACGACGGCGAGGTCGTCGAACACCTCCGCGGCACCGAAGCCGAAGCATGCACGACCGCACACCGCTGGGTCGCGGAGTTCCTGGCCGGGACGCGCTGAGCCGAGCGGGTGCGCGGCGGGCCGGAGCCCGCCGCGCACTCGGTTCAGCGCCGGGTGATCTCCCAGAGCACGTTGTCGCCGTGCTGCTGGGTCCAGAACAGCCGCCAGCCTCCTCCGAACGGGGTCGGCCGCTGGGCGCCGAGGACGCCCTGCGGCGACGGGTCGCCGTTGGACGCGTGGATGCCGGTGATCTCGTTGTCGCCGTCGTTCTGGAACCCGGTCCGGCCGGACAACGCCGAGTCCAGCGTCGCCGACGGGTCGCGGCCCTCCGCGAGGAACCGCACCGGCTGGGCGCCGTGAGCGTAGTCGGCGCGCAGGTCGAACAGGTACGCCGAGTCCAGCAGCCCGCGCTGGGTGTGCAGGCTGTCGCCCGCGTCCTCGACGAAGGCGACGTGGTCATTGTCCAGGAACGTCACGTTGTCCAGACCGGTGTGCTCCTTGTCGCCGTTGTAGACCAGCGACAACGTGCCGGTGTCGGCCTTCGGGTCGGCCTGGCTGAGCTTGAGCACCGCACCCCAGCCGCCGTAGCCGTCGTTGGCCGTGCTGGTGGCGTTGGTGTCGCCGGTCTCGTCGAAGTAGAACTCGCGGAAGCCGCTGCCCGGCCGGAACTGCCCGTTCTCCGGCCGCTTGAACGGGGTGGCCCCGGCCGCCTTGGCCAGCGCGTTCGCGTCGAACCCGGCCGAGGCCGGATCGGTCGCGGTGTCGTGGATGGTCACCCACTTCGTGCCGAAGGACAGGCCGTAGGTGTGCAGGTCCTTGGTGTCGTCGCTGAAGGCGTTGCCCTGCGGATGCGCGGCGTCGATCGGCTGGAACGCGATCGGGGCCCCGGTGCGCCGCGAGAACACCTGCAACACCTGCAGCTTGCCCTGCGTCAGATCGCCCCTGTCGCCCGGCACGTAGCGGTAGACGAAGCTGTTGGGCAGTTTGGCGTTGGTTCCGGGCACGGTGGCGCCGCCGGAGTCTTCGACCACCCACAGGTTGCCCGCGGAGTCGTTCTGGATGCCCTCGTAGCCGCCGCGGCCCAGCGCCCCGGAGATGTCCTCGGTCCGGGATCCATCCAGAGTGGACTGCCAGACACCGCCGCCGGCGCCGAGCTCGGCGGTGAACAGCAGCCGCCGCGCCCACGGGTCCCACGTGGACCCGTCGAAGTTCGGCAGCGGCTTGCCGTCGGTGGTCGCGGTGGCCAGCAGCGTGACCCGGTGGGCGGTGTCGGCGTCGAGGTTGACCCGCGTGATGAAACCGGTGGCGCCCGCCTCGTGGCCCTGGAAGACGAAGTGCGTGCCGTAGTCGTAGTGCGGGTCGGCACCGCGCTGACCGTGCAGCACCAGGTAGGTGTTCTTGTCCGGCTCGGTCTTGGACGCCTCCACCAGGTGCCCGGCCGCGGGCAGGTCACCCGGGGCCGGCAGCAGCGGACCGTCGCCGCGGTAGCCGAAGAACGGGATGTCCGCGACCGGGTTCTCCAGCCGGTTCGAACCCTGCGCAGCGACCCACCCGGCCAATTCCGGGGACAACGCGTTCGCCACGGTGAGCCCGGCCACCTTGGCGTTCGCCGGGACCCCGGTGAGCGCGAGACCGCGACCGGCGCCGTGCTGGCCCATCCCCTGCGCCGGCGCCCCCGCCACCACCGTCGCCGCCAGGGCCAGCCCGCCCGCGGCCACCAGCACCGTCCTGGCCTTCGTTCGCCTGCTTGGTCTCATCTCGAAGCCTCCAGCGTCCGGGAACACCGAGAGCCAAGACGGCGAAAGACACGGCAGCGGCGCGGTTCGATGACCAGCGGACGTACACAGACCCAACAACCGCTAACTGGTGCACCGAGGACGAAATACCACGGCCAGTGCGCGAATTTCCCTTACCAAGCAACAACTTCAACGGAAAATGCCCGCCGCCGGTTCCGACTGGGTCGCGGGAATCGCGTCGAAGCCCCGGACAGGCTCGCCCTGACGCGCATGAATTCCCCGCGGGCCGGGTATGCGGCCGACATGACGACTTCACCGTTCGAGCCGGACCCGAAGCTGGGTGAGCAGGACATCGCGGCCGCCGACCCCGGTCAGGGGGCGCCGAACACCGCCGAGGGGTTCGGCGCCGGCGAGACCGGACCTGATGTGATCATCCCGGAAGACGCGGGCACCGAAGAAGACCCGCGATAACAATCGGGCAAAACGGGTATCAGATCTTCATGACCGAGGGTCGAGTGGCGGTGTTCGCGCCGTCCCCCCAGCTGACGGTGACTGTGGAAGAGACCGCCGGGGTGCCGGACGTCCACGTGCATGCGGGTGGGCAGGGGGTGTGGCAGTCGCGGATGATCCAGTCGCTGGGAGCCACCCCGGTGCTGTGCTGCGCGCTCGGCGGGGAGACCGGGCAGGTGCTGCGACACCTGATCGGCGTCGAGCTCCAGATCCGGGACGTCGCCGCGCGCAACGGCGCCTACGTGCACGACCGGCGGGAGGGCCACCGCGACGAGGTGGTGCGGATGCCGGCCGACGCGTTGTCGCGGCACGAGCTGGACGACCTCTACGAGCTGACGCTGGTCGCGGGCCTCGGTGCGGACGTCACCGTGCTCAGCGGCCCGGCCGAGGACGACGTCCCGGTGCCCCACTCGGTGTACGAGCGGCTCGCCCGGGACCTCGCCGGCCAGGGAGCCCGGGTAGTGGTGGACCTGTCCGGGGAACGGCTCGCCCGGGCGCTCGCGGGCGGCCCGGAGGTGGTGAAGGTCAGCCACGAGGAACTGGTGACCGACGGGCTGGCGGAGTCGGACACGCTGCCCGACCTCGCGAAAAGCTGCCGCGAGGTGGCGAAGTGTGGGGCGCGCGCGGTCGTCGTGTCGCGGGCGGCGGAGGACACGCTCGCCCTCGTCGAAGATGAGCTGTGGCTGGTGGAGTCGCCCGAGCTGACGCCGGTGGACCCACGCGGCGGCGGCGACTCGATGACCGCGGGACTGGCGGTCGGCTTGGCTCAGGGCCGGTCGCTGGAAGAGGCGCTGAAACTCGGAGCGGCGGCCGGAGCGGTGAACGTGACGCGACACGGCCTCGGATCGGGCAGCAGCGCAGCAGTGCGCGAGCTGGCGCGGCGCGTGCGCCTCAAGAACTGGGAGGACACCGGATGCGGGCACTGATCACGAACGACGACGGCATCGGCTCACCGGGACTGGCGGCGCTCGCCCGCGGCGCGGTGGCGCACGGCTGGACGGTCGTCGTCGCCGCGCCCGCCGAGGAGGCCAGCGGGACCAGCGCGGGCCTGTCCGCCGCCGGGGACGACGGCCGGATCACCGTCGAGCAGCGGCAGCTGCCGGGCCTGCCGGACGTGCCCGCCCACGCGGTCGCGGCGCATCCGGGGCTGATCGCGCTGGCGGCGGCGCAGGGAGCGTTCGGCGAGCCGCCGGAGGTCGTGCTGTCCGGGGTGAACCGCGGCGCGAACGTCGGCCGCGCGGTCCTGCACTCGGGAACCGTCGGGGCGGCGTTGACCGCGTCACTCAACGGGGCCCGCGCACTCGCCGTGTCCCTCGACGTGGGGCTCGAGCCGGGTCCGCACCAGCATTGGGACACCGCGGTCACCGTTGCGGCGACACTGTTCGACCGGCTCGCCGCAATGCCGGCCGGGACGGTCCTCAACCTGAACGTACCGAACCGGGCCGAGGTGGGGACGCCGCGGCGGGCCGGGCTGGCCGAGTTCGGGACGGTGCGCAGCCACGTCGAGAACGGTGACGACGGAGCGATCAGCCTCACCGCCGTCGTCGTCGAGGGCGATCTGCCGCCGGGCAGCGACGCCCGGCTCCTGGCCGAGGGCCACCCGACAGTGACGGCACTGCGATCGGTGACCGAGGACCCCAACATGCGGCTTTGACCGGCCAAAGCGGGGTTCGGCGGCGCCCGGCCATGCGGCGGCCCGTCGACGGACAGTGGACTCGAGGATCGTCAGCGTGGCTTTATGGACAAACTGGAAACCGCCGAGGAAGCGCCTGCCCCGGCACAGCCTCCGTCCGGGCGACTTGGCACTCATGGCCGCCCCCGGAATACCTGCCAGTAATCATCAATCCACTGCCACGTGTAGCCCTTATCCTTAAGATACTTGAGCTCCCGCTGATAAGTATTCCCCATCCTGCATAGCGGCTTGCAAGGGTCGGTGACCAGGCGCACGTCACGATCGCCATTGAGCCTTGTCCCGGTCGACGACGACCCATTCTCGAAACCTCCGCCCGGCAGGGACGAACGGCGCGCCGTTGCCCGCATCGACGCGCTGACATCGGTGAAGAAATCGGACGGTCGCTCAGGCATCGCTCAACTCCGGACCGACCTGGAGCGAGTAGTAGCCGGTGGTGGCCAGCCGGCGCGACCACGACGCTGCCGGGCCTTCCACGGTGACCTCGCCACTGACGAGCCCGTCGGCCCGGCCGGCTTCTCCGGCGGCCCGGGGGTCGAGAAACGCAGAAGTGGTCGTGCTGACGCACGCGTCCAATCAACGTCCAGTCGGCATCCAAGGTGGCGCAGCAGGCTGGTGCTCGTCAGCACCGGGTGGTCCCCAACCCGGGAACCGTTCCGGCCGATCGACTCCAGGAGATGCTCTATGCGTAGGCAATTCCTTGCTCACGGCTTCATCGCCTCCTCGGTGGCGAAGCCCTTGGTCGTCCTGGTAGCACTCATTGCCGCCTTCGTGGTCGCCCCGGGTGCGGCGTCCGCCGCATCCGGGGGCGACACCTCGGCGACTGCGGGATGGAGCACCTTCCCCAAGCCCGTCACCGACACCTCGAAGCAGCTCAGCAGCGGCGAAGCGAGAACCGACACCGTCAATGCGGTCTTCACCTGCAACTACTACAGCGTCTCCCCGTACTACGTCATCGACTTCACCTGCAACGTGACGCAGGGCGCCATCCAGCTCTGGGTGAACTGCACGGACGGACGCCACCTGCTCAGCGGCATCATGCGCGCAGTCGGCACCTACAACGCGCGGTCCATCTGCGGCCCGCCCGCGAGTTTGGTCAACTTCGGCGCCAACCAGCTCGCCTGAACTGAGAACGCGACAACCGACTGGACCGGTCCTCTTCGCCGCGCGGCGGAGAGGACCGGTCCGCACCATGTGCGAAACCGTTCCGGCGACAGGCGTTCCGTGTTGCGAAGGGCCGGCGTTGTCCGGCCCGAATCACCCAGAACCGTCAGAGCACCGGACGTTGTTGCTTCCGGCCCTCCCCTATTGACAGTACGTGAATCGCTGCGAAGAGTGGGCGATCTGTGGCTGCGCAACTGGAGGTGGCTGTGCATGTACAGGTGCTGGGGCCCGTGCGGGTGTGGCAGGACGGAGAGGAACTCGATCTAGGTCCACCGGGCCGTCGGGCCCTGCTCGGGGTTCTCGCGCTGGCCAGGGGCCGGGCTCTTCGGCGGACAGCGCTGGTTGACGCGTTATGGGGTGACACGCCGCCACCGAGCGCGACGAACATCATCCAGACGCATGTCAAACACCTGCGGCGAGTGCTCGACCCGGAGCGGCACGCGTACGCGCGCAGCCAGCGGATTCCTACGGTCGGCGACGGATATGCGTTGCGGATCTCACCGGATCAGAGTGACGTGGACCGGTTCTACCGCCAGGTACAGGCCGCCGAGCAGGAACGCCAGGCGGGCCGGTCGGATCAGACGGCGGCGATGCTGGGCGAGGCGCTCGGGTTGTGGCATGGGCAGCCACTCGCCGACCTGCCCGCTCTCGTAGGCCACCCGACGGTTCTCACGCTGTTCGAGGCACGGCGCGACGCGGTGCTGGCCTACGCCGAGGCGCTGCTCACAACCGGACGTGCCTCCGAAGCGTTGCCGGTCGTCATCGAGGAGACGGCGACGCACCCGCTCGACGAGGCCCTCGCGGCCATGCTCGTCCGGATGTACACAGCGTCCGGACAGCGGGACAAGGGATTTGCCGTATACGACCTGACCCGCAAACTGCTCGCCGCAGAACTGGGCGTCGCCCCCGGACCCGATCTGGCCGAGGCACACGCGATGCTCGTCCGGGAAACAGCCTCGACAGCGCCGTTCGCGTCGAAGCGACACCTACCGGCCGAGCTGCCGGCGAAGGTGTCAGAGGTGGTCGACCGGGCACGGCAACAGGACGAGCGCTTGGCCGGCCAGGTGGTGCCCGCCCGCCACCGAAGCGGGCGCCGGACAAACGCCTTGGCTCGCTACGAACAGCTCAAGCAACACCTGGGTATCGACCCCGGCCCACCGCTGTGGCAGGCGCACCACCACGTCCTCACCGCCGAGCCGGCAGTAGCCACCCCGGTAGGCACCGAACGTGCACCCGTGCCCCGCCAACTGCCCGCCCCACCGCGGCCGTTCACCGGCCGGGTCGCCGAACTCGCCGAACTCACCGCGGCAATGCGGGCCCAAGCCGAACCAGGCGGCACGGTGGTGATCTCCGCCATCGGCGGCACCGGCGGCATCGGCAAGACCTGGCTCGCCCTCCACTGGGCTCACCAGCACATCGACCGTTTCCCCGACGGGCAACTGTTCGTAAATCTTCGCGGCTTCGACCCTACCGGCGACCCGCTGACCACACAGACGGCGGTGCGCGGATTCCTGGCGGCTCTGAGCGTCGAGCCCTCGGCCATCCCGGCCGAACTGGACGCGCAGGTGGGGTTGTACCGCAGTCTGCTCGCCGGCAAACGAATGCTGGTCGTACTGGACAACGCCCGCGACACGGCCCAGCTCGCACCGCTGCTTCCGGGCAGCCCCAGCTGCGCGGTGCTCGTCACGAGCCGCAGCCGGCTGTCCGGGCTGGTGACCGCACACGACGCCCACCCGCTGACGATGGACGTGCTCTCCGAATCCGCAGCTCGTCAACTGCTGCAGGCTCGGCTGGGGGCCCAGCGGCCGGCCGCCGAACCTGGTGCGATGGCCGAGTTGATCGCCTGCTGCGGAGGATTCCCGCTGGCGTTGAGCATTGTCGCCAGTCAGGCCCGAGCCCACCCGCAATTCCCGTTGGCGGCACTGGCCGCCGAACTGCGCGACGCCTCGACGCGGTTGGGCGCTCTGGACGACACCGATCAGGCCGTCGGCGTACCGGCGGTGCTGTCGTGGTCCTACCGCGCCCTCACCCCCGAAGGGGCGCGGACGTTCGGGCTGATCGGTCTCGCGCCGGGACCGGACATCGATTTGCCGGCCACGGCCTGCCTCACCGGCTTGCCCATCGACGCGGCCCGGCGCGTGTTGCGCGCCTTGGACCAGGTTTCCCTGGTGCACCAGCATGTTCCTGGCCGATGGCGGATGCATGACCTGGTCCGGCTCTACGCCGCCGACCAGGCCCGCCAGGATCAGCCCCATGCCGACCGGGAGGCAGCGCTGCGCCGGGTTGTGGCCTTCTACCTGCACACCGCCGACGCCGCCGACCAGCTCCTGGACCCCCACCGCCAGCCCATCCGGCTCGATCCGCCCCCACCCGGTTGCCTTCCCTACCCGTTGTCCGATGCCTCGGCGGCCCTGGCCTGGTTCGACACCGAGCACGCGTGCCTGCTGGCCGCCCATCGTGCCGCGATCTCGAACGGGTGGCACCAGACCGTGTGGCAGTTGACCTGCACCCTGTTCACCTTCCACCACCGCCGGGGACACCGCCACGACCTCCTCGCCGTGTGCCGGACAGGTGCGGTGGCCGCGGAACACCTCCCCGACCCCGACATCCACGTCCGTGCTCACCAGCGTCTCGGACGTGCCTACGCAGATCTGTGGCGACTCGAGGAGGCGATCGACCACCTGCGCCGGTCTCTCGCAATCGCCTGTCAATACCACGACCACACCAACCAGGCCCACGCCCATCACGCACTCGCGCGGGTCTGGGAGCAGCAGGGCGACAACCGACTGGCCCTGGAGCAGGCCACCCACGCCCTGAACCTGTTTCGCTCCCTCGACGATCCGGTATGGCACGCCGCCACGCTCAACATGGTGGGCTGGCTCTCCGCCCAGCTCGGCGAGTACGAGCAGGCCCGCCGGCACTGCCAGGCCGCGCTGACCCTGCAGCGCCACCACCAGGACCCCGACGGTGAAGCGATCACCCTGGACAGCTTGGGCTACATCGATCACCACACCGGCCGCCACCGTCAGGCCATCTGCCACTACCAGCAGGCCCTCACCCTGCGCCGCGCCATCGGCCACACCTACGAAGTCGCAAAGAATCTCGACGCGATGGGCCGGCCGTACACGGCCCTCGGCCAACCTGATCAGGCCCGCGCGGTGTTGCGGGAGGCGTTGGAGTGGTACCGGCAACTGGGCCGCGGGGAGGACGCTGCACGGGTGCAACAGCAACTGGACGACCATTTCCGCGACCTGACACCCTCGTGATCGGCTCGACGTCGGGGACCCCGCCACATGCACCGGCCCTTCACCATCCTCGGACTCACAACCTGATCAACGATCTTGGAACGACCGCGCGGGCTGCGCCGGTCGATAGGCGAGACCGGGATCGCTGGGACAAACAGCGCAGCGGAGTCGTTCTGGTCGACGTCCAAACGCGAAGGGTACAACCGGCACATAGACGGACTCGTTGCCCGCGATTGACACGTCGATCCATTTCTGGGACAGTCGACAGCGGCACTTCGCAATCGAGATCCCGAGTTCTGGCGACTACGAAAAGTCGCCGCCAGCGGCTGCGTGAATCGCGTGAGCGCCTGCCCGCCGTTCAGCGTAAATCTCAGGGAACTCTTACCGATCCGAAAGTCCCAGGTCGCCTTCCCGGACGGTCAAAGGGGCGTTGGGCAGCACTAGCCTGCTTTCCGCAAGGCTCCAGTTGTGCGGAATACGGCCGCGCGGTTGACCGAAGGTGCAGCAATGCTGTCCGAACGCATGAACGAGCGTCCTCGCACGGGACCCGGCGAATACACGCGATCAGTGCGAACAAGACCGGGAGAGCAAGTGACCGTGGTGGAAGGCACCGTCCCTGCCGGGAAACTGGTCGCCACCGGCCGGTGGAAGCATGGCCGCGCACCCGAGGGTCAGGACGAGCGGGAATGACAGCCGTCGTCGCGCCCGGCGCCCTGCCGCTGATCGGTCATCTGGTTCCGTTGGTGCACAACAGGTTGGAGTTCCTGAGAGAGCTGCCAGCGTACGGGGATCTCGTCCGGGTCCGCGTCGGTCCCTGGCAGGCACTGGTCGTCACCAGTGCCGAATTGACCCACCAGGTGCTGCAGGACGACCGCACGTTCGACAAGGGCGGCTACCTGTACGACCGCATCCGGGAGACCGGGGGCAACGGACTCGTCAGCTGCGCCCATCGTGACCACCGAAGGCAGCGTCGCCTGGTGCAGCCGTCCTTTCACCGCGACCGGCTGCCCGGGTACCTGCAGGTGATGAGCAAGCAGATCGACGAGGTGCTGGGGCACTGGCGGGACGGCCGGGCCGTGGACGTCCATGCCGACATGCAGACCGTCACCGCGCGCACGATGCTACCCAGCGGCCTGCCCTCCTCGGTCATGGCGCAGATGATCGAGGACATGAACGTCGTGCTGGCGGGTGTGGTGTGGCGTTCGATCCTTCCCCGGAGGCTGGACAAGGTCCCCCTACCGGCCAACCGGAGGTATCACCGCGCACAGGAACGGCTCAGGCGTATCGTCACCGAAGTCATCGCCGACTACCGTTCGAGCGACACCGACCACGCCGACCTGTTGTCCGGCCTGCTCGCCTTCTGCGACCCGCACGACGGCGCGCCAGGCCTGTCCGACGCCGAAATCCACGACCAGGTACTCACCTTCCTCTTGGCCGGCACGGAAACCACGGCGAACGTGGTGAGCTGGGCCTTGCACCTGGTGGCACGGAATCCTGACATCGAACGACGGCTGCGCGCCGAAGCGGCCGGTGTCGCAGGCACCACACTGGACGATCTGTCGCGGCTCACTCTGGCGCGCAACGTCATCCTCGAGACGGTGCGGTTGTTCCCCCCGGTTCCCCTGCTCACCCGGATCACCACGAAGGACACGCGGCTCGGCGGGCATTTCCTTCCGGACGGTACCACCGTGGTCTACAGCCCCTACGTGGTTCAACACCAGGGTGCGCACTTCGCGGACCCCGAAGACTTCCGGCCCGACCGGTGGGACGGCGATGGGGAGCCGCTGCGACCGCCGCGCGGGGCGCTGTTCGCTTTCGGTGGTGGCGCGCGCCGGTGCGTCGGCGACACCTTCGGGCTTGCCGAAGCCATGGTGATGCTGTCGACCATCACACATCGGTGGTCGATGCGGTCGCTGCCGGGTTCGCGGGTACGTCCCGCGCAAAGTCTGGTGCTCGGTCCCCGGACCCTGCGCATGCGTCCGCAAGCGGCGACCCCGGGAGCATGCTCATGACTCGCGCCGAGCCTCGGGACAACTGGTTCTATCCGCGTGACATCGAGGACGATCTGAAGGGCACCGACCTTCCCGAGGAGATCGTCGCCGAGACCTTGGCCTGCGCGTGGGAGTACACCCGATGCGTGATACCCCAGTTCATCGACTGGGATCGGTACATCGCCTTCACCCGGATCATCGTGATCGGGATCATCGCAGAGTTCCGCGGCGGTCTGGTGGACGTGGCCGCAGGCGACAACCTGTTGGGCTACGACCTGGACGAACTGCTCGACACCGTGTTCGCGGGCACTCCCGGACACGAGGAGATGGCCCGCGAATACCGCACCTTCCTCCTCATCACCGCGGACAAATCGAGTGAGCGATGCAACTCGGAACTGTTCCGCCGGTATGTGAACGCGCTTACCCGGTCCCCCAAGGACTGGTTCCGCCTCCGTGACAGCGACGCTCTCGCACGGTTCACGATAGCCGCCGCCATGGCGTGCAACGACATCACCGACACATGGTTCAGTGAGGAGGAGTTCCAGATCCTCACTGAGCTCGGCGACACCCTCTACGACGCGGTCGCGTACTACAAACACCGCGCCGAGGGGGAGACCAACAGCACGTTCGCCTACGTCGGTCACGAACTGCGCGCCGAGTCCTATCGCCGCTGCCGGGAAGCCCTCTGGGCGTTGGACGTGGCATGGGCACGCGCGCCCGCGCACCGGGCCACCATCAATTTCCTGCGATATTTCGGCGGGCCGATCCACATGATGATGCGGAGATACCGGTTCACCGAGGAGGACCTGACGATCGGGAGGCCCGAGACCGAGCACGTGGTGGCTCAGACCCGCCAGAACATCAAACTCTGGCATCGTGTCGACGTGACCGAGAAGAGCACCCACAGCGTCCGCTACGCGAACGTGGTCGCCCGCAGCGAAGAACTGATGTTTCCCGGTTTGGCCGACATGCTGGAGAGCGCCGCCGACGCGCACTGCGACCACTGCCGCCACCGCCTCTCTTACGGCGCCGAACCACTCGGCCGGTTCGGCGGCGTCGAACTCTGCGACAGCTGCCGAGCGGACTGGGCTACCTATTTGCGAACCTTCCCGGCCCGCGCGGCGGAAGTCTTCCCGCTCGTTGGCGTTGAGCAGGCGATCGTGGGCTTGGCGTAGTGCTGCGGAGAGCCGCCGGACGCCGAGCGCACCGGTGACGCGTGCAAGCGGCCGTCCGGCGGTAATTCCCCGTACCGGGCGTCCTACCGGTGTCGACGCCGGCGTTCCCCCGGCGACCGCCGCGTGCTCACAGGTCCCGGTGGTCGACGCGGTCGAGGACGGTGTCGGGTACCGGACGGCTGGTGGTCACCCGGAAGTCCTGCACGGCGTCGAGTGTGAAGGTCGGGACGCCCGTGGCCTTGTCCGCGCGGACGTGGTGGAAGTCGGCGTCGGTGACGTCCCTGAGCATGTGGGCCGGCCGGGTGTCGGTCCGCTCGTAGCGGACTTCGACGTTGTCGAACGTGAGCCCCCTGGCGTGCCTGATGAACCAGCCGTAGGCCGGCAGCGTGCCGAACATGGCCGGCTCGGGGTAGCCGGTCTCCAGTTCCGGCGGGTTCGCCACCGCGTCGGCGGGGGTCAGGCCGCCGGCCGTGTGCTGCCGGACGTTGCTGATCCGGATGTCCTCCACGTTGTGCCCGGGAATGCCGGCGATGGTCGACGGGTACTGGGGGTCGGTGTTGGCGGCGACGACGTCGCTGATGCTGACGCGGCGCAGCGTGCCGACCGGAATCCCGGCGGGACCGCGCATCCGGGCGCCCAGCCGGAGGAAGATCGGCGTCTGCACGTGCCGCATGGTGAGGTTGCTGATCGTCACGTCCTCCAGCACCCCACCGTCCACGGTCTCCAGCGCCAGCCCGCGGCAGTACTCGAAGACGATGTTCGAGATGGCGATGTTCTTGAACCCGCCGTTGGACTCGGTGCCGAACTTGATCCGGCCGACGCGGGAGTAGGGGCCGGTCCGGAACGTCCCGTCGACCAGCGTCCCGAGGTCGTAGCCGCTCACCAGGCAGTTGTCGATGGTGACGTTCTCGGTCGCTCGCAGCTGGTTGAGGGCGTAGGAACTCTTCAGCACGATGCCGTCGTCGTAGGGCGAGTTGACCGTCGTGTTGGCGATGCGCACGTTGCGGCAGCAGTCGAGGTTGATGCCGTCCCGGTTGGTGTCGATGACCAGGCCGTCGATGCGGAAGTTGTCCACGCCGGTGGGCAGGACGGCGAAGTGCCCGCCGTTGACGATGGTCAGGTCGCGAATCGCGATGTTGCGGCACAGCTTGAGCGCGATCGCCTTGTTCCCCTGCAGTGGCGCGGATTCCTGGTCCCCCGAGGCGACGAGGCCGGAGCCGTCGATCCGGCCCGGGCCGTGGAGGGTGACGTCCTCGACGCCCTCGCCCCAGATCAGGCTGTTGTGCCAGTGGCTGTGCCCGAAGTCCTGGTACGGGTTGCCCGCCCCCGGCTCGGCGGGGTCGTAGCCGCGCCCGCCCGCCGGCTTGGCGGCGAGCAGGGTGGCGTTCTGGTCGAAGTACAGCGCGACCCGGCTCCTCAGCCGGATCGAGTAGCTCGCGTACTTCCCGGGCGGGAAGTACACCGTGCCACCGGTGCTCGCCGCCGCGTCGATGGCCCGGTTGACGGCGTCGCTGTCGATGGTCGTGCCGTCACCGGCAGCGCCGAACTTGCGGACGTCGAACACGGTGCCGGTGGTCCCCACGGGGTCGGCGACCGCGGTTGCGGTCCCGGCCAGCGGGGCCGCCAGACCGGCGGCTCCCACGGTGACGACGCGACGACGACTCAGGAGCATGTCCATCCACCTCATCAACGGAAGGCCCGGCCGGAACCGGCTGATCGGAAAGTGTCTTCGCGCCGCGGCCGGTGATCCTCACGTCGTTGTGGGAGACCGCCGGCCGCGGCGCCCGCCACGTCAGGTGCCGAGGGTGACGTGGAAGATCTTTTCGTTGCTGTTGTTGGGAATACTGTCCTTGTCGCCGTTGTTGGTCGTCGTCAGCCACAGGCCGCCGTCGGGGGCGGGCTCGACGGTGCGCAGCCGGCCGTAGGTGCCGTTGAAGTACGTCTGCACGTTGGTCAGTTCGCTGCCGCTGATCACCTCGCGGTACATCCGGGTCCCGCGTTCGCAGGCGACGTAGAGCACGTCACGCACGACGGCGATGCCGCTGCAGGAGCCTTCGGCGACCGGGTAGGTGTGCTTCGGCGTGATGAACCCGGCGGTGCCGCAGCTGCCCGAGGTGCCCTCGCACGCGGGCCAGCCGTAGTTGCCGCCCTTGGTGATCAGGTTCGTCTCGTCCATGACGGAGTTGCCGAACTCCTGCTCCCACAGCCGGCCTTGGGAGTCGAACGCCAGACCCTGCGGGTTGCGGTGCCCGTAGCTCCACACGTAGTTGCCGAACGGGTTGTCCGAGGGCACGGTGCCGTCGGGGTTGAGCCGGAGGACCTTGCCGTTGAGGCTGGTGGTGTTCTGGGCGTTGTCGCCGTTCTGGGCGTCGCCGGTGCCGGCGTAGAGCTTGCCGTCGGGGCCGAAGCGCAGCCGGCCACCGTCGTGGAACTTGTTGCGCAGGATCCCGCTGAGCAGGATCTGCTCGCTGCTCGTGGTGAGCTTGTCGTTCTCCAGCTTGATCCGCACGATCCGGTTGTCGGAGGGCGAGGTGTGCATGATGTAGAGCCAGTGGTCGCTGCCGTAGGTGGACGAGACGGCCAGGCCGGTCAGGCCGCCCTCGCCGTCGGTGCTCTGCACGTTGGGCACGGTGCCGACGGTGGTCTTGGCGCCGGTGGCCGGGTTGAGGTGGACGATGTCCTGGGCGTCGCGGCGGGTGTAGAGGATGGTGCCGTCGGGCAGGGTGGCCAGGCCCCACGGGATGTCGGTGTCGGTGGCGATCTGCGTGACCGCGCACACCGAAGCGCCGCAGGCGCCGCCCGTGGTCACGGTGGCGGTGTTGCTGTGCGCGGAGACGTTGGCCTGCGCGTCCCGGGCGACCACGTAGTACTGGTAGGTGGTGTTCGCGGCCAGGGCACTGTCGGTGAAGGTCGTGGCCGGCGGGGTGCTCGCGGTGCCGGTGACCGTGCCGATCTTGGCGTTGTCGCGGTAGATGTCGTAGGCGCGGACCCCGATGTTGTCGCTCGCGGCGGTCCAGCGCAGCGTGACGGTCGTGCCGGCCGCGGTGCCGGACAGGGCGGCCGGCGCGGTCGGGGGCTGGGTGTCGGCCTGGCACTGCGGCGGGGTGATCGGCACCGTCGTGCTGGCCTGCGAGACGTTGCCCGCGGCGTCCCGGGCGTTGACGTAGAGGCCCCAGGTGGTGCCGGGCACGACGGTGAGGTCGGTGGAGAGCGTGGCACCGCTCACCGACTTGATCAGCTGGCCGTCGTGGTAGACGTCGTAGAACGCCACCCCGACGTTGTCGGTCGACGCGTTCCACGCGAAGGTCACCGTGTCGCAGGCCAGGTTGCTCACCCGTGGGTTGCCCGGCACGGTGGGTGGCTGCGTGTCGCCGCCTGACGCCGTGCGCCACTGCTGGTTGGCTTGGCCGTTGCACGTCCACAGCCCGACCGCGGTGCTGTTGGCGGTCCCGGCGCCGGTCACGTCCAGGCACAGGCCCGACTGCACGCCGACGATCGTCCCGGTGGAGTCGATCCGCCACTTCTGATTGGCCCCGCCGTTGCAGGTGTAGATCTGCACGACCGCCGGTGCGGTGGTGGCCTGACCGGCGACGTCCAGGCACTTCGGGCTGTCGTACACCCGCAGCTCGCCGGCCGCGGTGAACGTCCACGCCTGGTTGGCCTGCCCGTTGCAGTCGTAGATGTCCACGCCGGCCTTGTCCGCCTGCGACTGGCCGACCACGTCCAGGCACCGCCCGGAGGCGACCCCGACGATGGTCGAACCGGTCACCGCCGCCGCCGGCACCGCGACGGCCCCCACACCCGCGACGGCGGCCACCACCGCCGCGGTGAGCCGCACCGGCGACCACCGTCGCCTGTTCGAGGTGAACGCTTTCATCAGACCTCCACGTCGAGATCAACGATCGACCGGCCCGCACGGCCGGCTCGGCGCGGCACCGGCCGGCACCGCGTCCGGGAACACGGATGGCGGTCCGCCCGGGATGTCTCCCCAGCCGGAAGCCCGCCGTTGTGGAGCCGGAGAAGGCCGGACCTCCGCCCGGGGGGGGCCGGCCCTCTCCGACGATCAGGACGGGCGCGGCGTCAGGCCTTGGCCCACTTCTGGTTGCTGCCGCCGGAGCAGTCCCAGATCTGGACCTTGCTGCCGTTGGCGGTGGCGGCGCCGTTGACGTCGAGGCACTTGTTCGCGCCCACGGCGGTGATGCTGCCGTCGCCGTTGAGCCGGAACTGCTGGTTGCCGCCGCCGGTGCAGTCCCAGATCGCCACCGCCGTGCCGTTGGCCGTGGCGTTGCCGGACACGTCCAGGCACTTGGTGTTGCCGTAGACCCGCAGCTCTCCGGCCGCGGTCGAGGTGAACGCCTGGTTCGCCCCGCCGTGGCAGTCCCAGATCTCGGCCGGCGTGCCGTTGGCCTGCGACGCGCCGGTGATGTCCAGGCACCGCCCCGATCCCTGACCCCGCAACGCGAACGTGCCGGGGTTGGCCACCCCGCCGCCGGTGACGACGTACATCGCGGCGCCGTGGCCCGGCACCGACGCGCTGATCGCGCCGCTGGTGGTGCCCGTGGAGTGCGCCCAGAGGTCACGCACCGAGTAGCTCGAGGCCGACCCGAGACCGATCTGTGAGGCGGAGGTGCTGATCGTGCTCGTGCCGCTGCCGCGGTTGAGCAGCACGACCGCCATGGAACCGTTGGCCATCGGCTTGGTCCAGACCTCCGTGTCGCCGTAGTCGGCGATCCGGTTGCCCTGCCGCCCGCCCCAGTCCTGGTTGACCCCGATGACTTCGGTGTTGGTCAGGATCGACCGCGTGGCGGCGCTCATGGTGCGCAGGTCGTTGCCGGCCAGCAGCGGGGCGTTGAGCAGCGCCCACAGGCTGAAGTGCGCCCGGGCCTCGGTGTCGGACAGGCCGTTGCCGACCTCGAGCATGTCCGGGTCGTTCCACGCGCCCGGTTTGGCGAGCCCGGCCCAGCCGGGCTGGGCGTCGAGGATGCCCAGCACCGAACCCCAGTTCCCCTGGATGTCCCAGGTGGTGCGCCACGAGTTGCCCGTCGCCGGCCCCCACTGGTTGACGCTGTCGCCACCCCAGTTGCAGATCGCGAACAGGATCGGCCGCCCGGACTTCGCCAGGGCGTCCCGCATCGCGACGTAGCGGTCCTGACCGCTACGACCCTGGTGATCACCGCAGTTGTCGTACTTCAGGTAGTCAATCCCCCACGATGCCCACAGGTTCGCGTCCCGCTGCTCGTTGCCCAGGCTCGCCGGGTAACCCTGGCACGTCGTCGTACCGGCCGAGGAGTAGATGCCCAGCTTCAGCCCCTTGCCGTGCACGTAGTCGGCCAGCGCCTTCATGCCACTGGGGAACTTGGTGTGGTCCGGCACCAGGTTTCCGCTGCTGTCCCGGTTCCACTCCGACCAGCAGTCGTCGATGTTGACGTACTGGTAGCCGGCCGCGGCCATGCCGCTGGACACCATCACGTCGGCGGTCTGCCGGACCAGGGTCTCGTTCACGTTGCAGCCGAAGCTGTTCCAGTCGTTCCAGCCCAGCTGCGGCGTGCGGGCCAGGTTGTTCTCCAATGCCTGGGCCGGCTGCTGGACGGAGAGCAGCGCGATCGGCACCGCGGCCGCGGCCAGCACGGCCGAAAACGCTGATCGCCAGAACTTGCGCACAGATCCTCCTCGGTGAGTCTGAGCGTCGTGTGCGGTCCGGTGGGACGCGGAGACCGGACGGCACCGGGAATGCCCGGTGCCGTCCGGGAGCGCTCCCAGAGGGGGCACTCGGAGGGGTGTCGTGGGGGTGGGTGGTCGTGGTGGTCTGCCAAGACGACGGTGCCGGTGAGCGGGCGGGCGCCGGGCCGGTAACGCGGAGCGTGCCGCGGAACCGGCCCCGACCAGCAGTTCGTTGCTTGGCGAAAGTATTCGTTGGAAGCCACCTGAAAATGTCAAAGTCTCCTGGTCCTGTCAAGCACCTCATCTGGCCAGACCACGGCGTCGTCCGCCTCCTCCGACGCCCCGGTCACCAAGCAGAGCCGGATTGACCTGCGGAAATCCCGGCGCAGGAGTAAATTTCATGATCCGGCACCGTCGGGGCGCCCGGAAACCCCGGCCGGGCGAGACTGCGCAGCTTGATGGCTTTTGTTCGATTCGACCACCACTGCGCGACCCGCACGCGTGCCGGACAAGATCGAATACTCCAAACAGGCGCTGATACTTTCCATATCGAAGTAATACCCCCGGCGCGGCCGGCTGCACGTGTGCGGCACCACGATGTGCGACAAGGACAACGCCCGCGTCCAGCTGCGTGGCGTGCGCAGCGTTCGCCGCGGCGGACGTCCGCACGGGCCTTTGCTTGGTCCCGCCGCCGTGTTAGCGTTCACACCGGCGGGCTTTCGTTGGAGCACGGCCAATGGCGGATCGACGTCGGAAACCGGCACGCCATACCGGCCGAACGTGGTGGACAGACAGGTACTCACGTCAACGACGATGGGAGTTCCCATGCTCCGGAAGCTCTTGTGCGCGGCCAGGTCCGCGACGGTTCCGCAGTGCCCCGATGAGCCACGGACGGTGATCCGTCCGGTCGGCCGGCGACGGGCTCGGCCGCAGCGCCGGGTCGTCCACCGGAGGCAAGTGTCGTGACCCTCGTCAACCGGCAGAGTCACCTCGCCTCCGACGCGTAGGAAGCCTCGGCCGCCGACAGCACGCACTTCCCGGTGGCACCACCCGGGCCACTCCAGCCGGCCATTCCGGTCGCCGCGCGCCCGACCGCGTCCGCGGCGGAGCGCTCCGCAGAACGCCGAAGGCGCCCTGCGGGAACACGCCGCGTGTGAACGACAACGGTTTGCCTGCCGGCTCGCTCCCCCGTGCCATTGCGCGTCCGGTCACCCAAGTCAAGGAGTCAACAGGAATGCCAAAACACAGAAAGCTGTTCCGGTCATGGGCCGCGGTGTCCGCACTGCTCGCGGCGGTCTCGGTGATCGGCGCCGGCGTCGCGCACGCCGACAGCACCGGCGCGCTCCGTGGCGTCGCCTCCGGCCGCTGCCTGGACGTGACCGGGCGCAGCCAGGCCGACGGAGCCCTCATGCAGGTCTGGGACTGCAACGGCGGCACCAATCAGCAGTGGACACTCACCGCGCTCAACCAGTTGACCGTGTACGGCACCAAGTGCCTGGACGTGCCCGGTCACGCGACCGCGGCCGGCACCCGGGTGCAGATCTGGAGCTGCAACGGCGGGACGAACCAGCAGTGGCGCGTCAACGCCGACGGCACGGTGACCGGCGTCGAATCCGGGCTGTGCCTGGACGTGAGCGGAGGCGGCGCCTCCGCGAACAGCACCCCGGTGGTGCTCTGGACCTGCAACGGCCAGAGCAACCAGCAATGGACCGGCCTGACGCCCACCGGGCCGGGCGGCGGGAACCTGCCGTCGAGTTTCCGGTGGACGGACCAAGGTCCCCTGATCAGCGCGAAGCCCGTGTCCGGGCACAACATCGTGTCGGTGAAGGACCCGAGCATCGTCCGGTACAACGGGCAATGGCTGGTGTACGCCACCACCGCGGACACGTCCGGCGCCTGGAGTGTCGAGTACACGCACTTCACCGATTTCTCGCAGGCCGCGTCGGCGTCGCAATACCACCTGAGCGACAACCCGAACCTCGGCCACCGGTACATGGCCGCGCCGCAGGTGTTCTACTTCGCCCCGCAGAACAAGTGGTACCTGGTGTTCCAGCAGGGACCGCCCGCCTTCTCGACCAACACCGACCCGACCCAGCCGCAGAACTGGAGCACGCCGACGAACTTCTTCGCCAGTACGCCGCCCGTGGTCGACCAGCACGGGGGCGGCTGGCTGGACTTCTTCGTCACCTGTGACACCGCCAACTGCTACCTGTTCTACGCCAACGACGCCGGTGACATCTTCCGGTCGCAGACCACGGTGGCGAACTTCCCCAACGGCTTCGGCAACACGGCGGTGGTGCTGCACGACGACAACCGGGGCAACCTGTTCGAAGCCACCGCCGTGTACAAGGTCAAGGGCTCCAGCACCTACCTGATGCTCGTGGAGGGCTGGGATTCGGTCGGCCACCGCGTCTACCGCGCCTGGACCGCGCCCAGCCTGAGCGGGTCCTGGACCCAGATCGCGAACCCGTTCGCCGGTCTGGCCAACGTGACGTTCCCCAGTGGACAGTGGACCAACGACGTCAGCCACGGGGAACTGATCCGCACCGGGTACGACCAGACCATGGAGATCGATCCCTGCCACCTGCAGCTTCTCTACCAGGGAGTGAACCCGAACTCCACGAACGTGCCGTACTCGCAGCTGCCGTACCAGCTCGGCCTGCTCACCCAGACCAACCCCTGCTGACCGCGCTGCCGTGCCCCGGCCGCATGAGCCGGGGCACGGCACCGGCCACCGTCCCATGGGAGCGCTCCCAGAGGAATCTCGTACACGCCCATAGGAGTCCCAGACATGCCCAGAGCAGTGCGTGCCCGACGCCCCTGGCCCCTGGCCACCATGGCGGTCCTCGCCGTCTCGACCGTGGTCACGGTCGCTCCCGCCGACGCCGCCACCGCCGCGCCGGGCCCCGACCTGGCCGTGGACGTCCTCGCCGATCGGCAGCCGATCAGCGAGGACATCTACGGAATGAACTTCGCGAGCGAGGAACTGGCCGCGGAGCTCCGGTTGCCCGTACAGCGGTGGGGCGGCAACTCCACCACCCGCTACAACTTCCGGTTCGACAACACCAACCGCGCCTCCGACTGGTACTTCGAGAACATCGACGAGGCGACCCCGGACCCGGCGGCGCTGCCGGACGGGTCGGTCACCGACCTGACCCACGAGCGGAACGTGCGCACCGGCAGCAAGAGCCTGTTCACCGTCCCGCTGATCGGCTGGGTGCCGAAGGCCCGGGGCAAGGCGTGCGGGTTCTCGGTGGCGAAGTACGGCCCCCAGCAGAGCACCGATTCGTGGGCCCCGGACTGCGGCAACGGCGTCCGGCCCGACGGCACGAACGTCACCGGGAACGACCCGCACGACACCAGCGTCGAGGCGGGCGCGCAGTACGTCGAGGACTGGATCCACCACCTCACGGGCAAGTACGGCACCGCGGCCGGCGGGGGCGTCCGCTACTACGACCTGGACAACGAACCCGACCTGTGGCAGCACACCCACCGCGACGTGCACCCGCAGGGCGCGGGCGCGGTGGAGCTGCGCGACCGCACCTACGACATCGGAGCCGCGGTGAAGGCCGCCGACCCCTCGGCCAAGACGATGGGGCCGGTGGGCTGGGGTTACATGTCGCTGCTGCACTCCGGCCTCGGCGACGCGGACCGCCCGAACCACGGCGGCGTGGACTTCGGCGAGTGGTACCTGGCCCAGATGCGCGCCTACGAGCAGCAGCACGGCGTGCGCATCCTGGACTACTACGACAACCACATCTACCCGCAGCAGTCCGGGGTCTCCTCGAGCGATGCCGGCGACGCCGGCACCCAGGCGCTGCGGCTGCGTTCGACCCGCCAGCTCTGGGACCCGACCTACGTCGACGAGTCGTGGATCAACGACAAGATCAGGTTCATCCCCCGGATGAAGGACATGGTCGCGCGGAACTACCCCGGCACGAAGACCGCCATCACCGAGTACAGCTGGGGCGCCTTCGACTCCGTGAACGGCGCGCTGGCCCAGGCCGACGTGCTGGGCATCTTCGGTCGCGAAGGCCTGGACCTGGCCACGCTGTGGACCGCTCCGAGCGCCGGCCAGCCGGTCGCCGACGCCTTCCGGATGTACCGCGACTACGACGGCCGGGGCGGCCGGTTCGGGGACACCCGGATCCGCGCCACGAGCACCGACCAGGACAAGGTGTCGATCTACGGCGCCGAGCGCGCCACCGACGGTGCCACCACCCTGATGGTCGTCAACAAGACCGGTGGCGACCTGACCAGCCCGGTGGCGATGTCCGGCCGGGGTGCCGGCACGGCGCAGGTCTACCGCTACAGCGGCGCCGACCCGACGGGCATCGTCCACGAAGCCGACCAGGCGGTGTCGGCGACCGGGTTCACCGCCACCCTGCCCGCCGGCTCCATCACCCTGTACGTCATCCCGAAGGACGACACGCCCACGCTCCCGGCGCCGGGCGCGCCCACGGCGTCGGACCTCACCGCGACCGGCGTCACGCTGTCCTGGCCCGCGGTCACCGGCGCGGCGGACTACACCGTCGAACGGGACGGCAGCCCGGCCGGCCGCACCGCCACCACGACCCTCGCGGTCACCGGCCTGAAACCCGACACCGCCTACACCTTCACCGTCCGCGCCAACAACGCCGCCGGCACCTCCTCGCCGCCGTCACCGGCGCTGACCGTGCGCACCAAGCCGGACCAGTCCGGCACCGGGTGCACCGCGGCGGTGACGGTGACCGGCAAGTGGCCAGGGCAGTTCCAGCTCGACCTGACCGTCCGGAACCGCGGCACCACGTCCGGCACGGGCTGGACGGCGAGCTTGGGCCTGGCCGGTGGCATGTCCGTGGCCCAGACGTGGAACGGGGTCACCACCACCACGGGGACCACCGCCACCGTGCGCAACGCCTCGTGGAACGGCGCGCTCGCCCCCGGTGCCTTCGCCACCGCCGGGATGATCCTCAACGGTGACCCGGCCGGCTGGACTCCCACGCCGACCTGCTCCCTGACCTGACCCACCGGCCGCGGTCGCGCCCTCGCCGGAGGGTGCGGCCGCGGCCGCACGCCGTCCGCCGCGGCGGTCCATCCTGATCACCGGGATAGCATGGTGCGGTGACGGCCGACGACCCGGGTTCCCCGCCCAGCATCGGGCCGGTCCCGAGGTTGGCCGCCACCACCTGGACGGGCACGGCGGACGGCACCCGCGCCCAGATCTTCGCCGAGGTCCTGACCTTCGGCCCGATCTCCCGCATCGAGGTCGCCCGCAGGCTGGGCCTGTCGCAGTCCACCGTCACCAAGGCGGTCACCCCCTTGATCGACTCCGGCTACCTCGTCGAGGCCGGCAGCAGGGTCGACGGCCCCGGCCGCCCGCAGCGCCTCATCCGGGTCGCGGCCGGCCGGTACCACGCCATCGGCGTCCAGCTCGGGCCCGCGGGCGTCACCGGCGTCCTCACCGACCTGCGGGCCAACACCCTGACCCGCCTGTACCACCCGCTGCCCGAAGGCCACGAACCGCACACCGTCCTGGCCGCCGCCGCCGGCCTCATCGGCAGGCTGCGTTCCGCCGCGCCTCGCGGCCTGCTCGGCGTGGGCGTCTCGCTGGGCGGCCACGTCGACCCGGCCACCGGCCGCTGCGTGCACTCCGGCATCCTCGGCTGGGACGACATCAACGTCGCCGCCCTGCTCACCACCGCCACGGGCCTGCCCATCGTCGTCAACAACGACGTCAACGCCGTGGTCATCGCCGAACAGTGGTTCGGCGCGGGCCGCGGCGTCCGCTCCTTCGCGGTCGTCGCCGTCAGCGCCGGCATCGGCTGCGGCCTGCTGCTCAACGGCGAACTCCACACCGGTGCCACCGGACTGGCGGGCGAATTCGGCCACCTGCCCCTCAATCCCGGCGGGCCGCCCTGCAGCTGCGGCAACACCGGCTGCCTGGAAGCCGTCGCCGCCGATCCCGCGGTCATCGCGGCCACCGCCGCCCAGGGCGGTCCGCGCTGCGACAGCACCGAAGAAGTGGCCGCACTGGCCCGGTCGGGCAACGCGGCGGCCCTGGCCGCCTACACGGCCATGGGCGAAGCACTGGGCCGGGGCCTGGCCGCCCTGTGCAACCTGCTCAACCTCGGCAAGATCATCCTCACCGGCCACGGTATGAAAGCCTTCGACGTGTTCGAAAGCGCGTGCCTGACCGCGTTCCACCGCCACGCCTTCTCCACCGCGGCAACGGATTGCGAACTCACCCTGGAGCCGGGCGGCGACGACCTCTGGGCCAGGGGCGCGGCCTGCCTGGTCATCCGCGAAGCGGCCGGCGCCGCACATCCCTGACCGGACGGGGTGGCGGTCCAGGACGGCACCGGACCGGATCCCTTGACCTCGCAAGACGTCCGTGCGGTCCCCCGAGCCGGAGATCGCCGCTGCCGGAACCGGTCGAGGCGTCCACAAGAGACACGAGTTCGCGCCCGCACGGGGAACCGGCGCACGCTCCCGATCCGGGGCACAGGCCTCGCGAGGTGGCCCTTGACCGGGCGCGGGAGCCGCCCTATCGTGAATTGGGTTTGTTTCCCGCAGAAAGTTACCCCTGTTCGCCCCGAACGCCGCCACCGTTGGCGTCCGTTCGACGTGGCCTTCCAGTGATGACTCCGCGAAGAGTTTCACCGGATGGCCCGGCCCTCGTCTGGGAGCGTTCCCAGACCAGGGGGACGGACGACGGCCTGCCAGACCAGCGTGGCGATGGAGGACCTGTGGCCCAGCGACAACGACGTCCGCTCGCCCAACCCAGCCCTCTCCTGGGGGACGAAAAGGCTTCCCCGGAGGCGAAGCGCACGGTCCTGCGGAGGCGTTCCGTCCTGGCCGGCGCCGGTGCGCTGGCCGCGAGCGCGGCTCTGCCCCGCCTCGAGCCCACCGCGGAGGCGGCGACGGCGAGCCGTCGCGTGGTGTACGACCTCAACCCGGACTGGCGATTCGTCCAGGCCGACGTCCCCGGGGCGAACGCGACCACGTTCGACGACTCCTCGTGGACGACGGTGAGCGTGCCGCACACCTACAACGACGTCGACTCGTTCGACAACTGGATCACCAGCTCCGGCGAGAGCGCGGTCGCCATGCAGATCACCTGGTACCGCAAGCACTTCACCATGCCGGCCGGTCTGGCCGGGATGAAGGTGTTCCTGGAGTTCGAACGGGTGCGGCAGGCGGCCACGGTGTACGTCAACGGCGTCCAGGTGGGATTGTGCGAATTCGGGGTCTCCCCGTTCGGCTTCGACATCACCGACCGGATCAGGTTCGGCGCGGACAACGTGATCGCGGTGAAGGCCGACAACACGAAGTGGCGGCCTGAGCAGGCCGGCGGGGTCGGGTTCCAATGGGACACCCGTGACTTCTACCCCGAGTACGGCGGGTTGACCCACAACGTCCGGATGCACGTGCTGCCCAGGACGTACTTCACGCTGCCGCTGTCCATGAACCTGGGCACCACGGGCACCTACGTCTTCCCGAGCGCGTTCAACATCCCCGGCGCGACCGCGGCGATCACCGCGCAGGCGCAGGTACGCAACGAAGACTCCGCCGCGCGGACCGTCACCGTGTCGGCGAACCTGATCGACGCCGGCGGCGCCCTGCACGCGACCATCGCCGGTTCGGCGGTCAGCGTGGCCCCGGGCGAGACCCGGGTGGTGACGCTCTCCCAACGGATTCCCGGCCTCCGCTTCTGGAGCCCGGCCTCGCCCTCCCTGTACACGGTCGAGATGGTGCTGAGCATCGACGGTGCGGTGGTCGACGCCTACCCGGTGGTGACCGGCTTCCGCAAGACCGCGTTCCAGGGCGGCACCACCGCCGGTGGCGTGTACCTCAACGACCAGTACGTCTACCTGACCGGGTATGCCGTGCGGACCACCAACGAATGGGCCGTCATCGGCGGCGCGGTGCCGGAGTGGCTGACCGGGCTGGACGGGCAGCTGATCCGGGACAGCCACGCCAACCTGATCCGGTGGATGCACGTCTCCGCCCCGCCCAACCAGATCCGGATGACCGACAAGTACGGCATCGTGTCCGTCCAGCCGGCCGGCGACAAGGAGTCCGACGTCACCGGCCGGCAGTGGGACCAGCGGGTCGAGCAGATGCGGGCCTCGATGGTCTACTTCCGCAACAGCCCCAGCATCCTGTTCTGGGAGGCCGGCAACAACTGGATCACGGCCGCGCACATGAGCCAGATGCTCGACCTGCGCAGGACCTGGGACCCCGCCGGCGGACGGGCGATCGGCTGCCGGGCCATCTCGGACAGCTCCGCGTACGGGGGAACCGCGGCCGTGGACGCGGCCGAGTACGTGGGCACCATGCTCAACCGGCACTACTCGGTCTACGCGCGCGACCGCAAACCCGTCATCGAGTGCGAGTACACCCGTGACGAGGCGCCCCGCCGGGTGTGGGACAACTACTCCCCACCCGACTTCGGCTACCGCACCGGACCGGACGTCACCTACCACTGGACGTCCGAGGACTTCGCCGCCACCGTCGCCGCGAGCAGCCGGTACGAGTTCTGGTCGCAGCGCATCCAGGGGCCCGGCGACCGCCGCTACGCCGGCGCCGCCGCGTTGATCTGGGCCGACTCCAACCAGCACGGCCGCCAGTACAACTGGGAGTGCGCCCGGCTGTCCGGTCGGGTCGACGCGGTGCGCATTCCCAAGGAGTCCCTGCACAGCTACCGGGTCATGCAGAACCCGGCGGCCGACATCCACGTCATCGGCCACTGGACGTACCCGTCCGGCACCAGGAAGACCATCCACGTGCTGGCTTCCGCCGCCGTCCACGAGGTGCGGTTGCTGGTCAACGGCACCCAGGTCGGCAGCAACAGCTCACCGGCCTACGACTTCCTGTACTCCTTCCCGGACGTCGCCTGGCAGTCCGGCACCATCACCGCGGTCGGCTACACCACCGGCGGCACCGAGGTCGTCCGCGCGTCCAAGACCACCACCGGCGCGGCGGTCGCCCTCAAGCTCACCCCGTACACGGCGCCGGGCGGACTGCGAGCCGACGGGAGTGACGTCGCGTTCTTCGACGTGGAAGCCGTCGACAGCGCCGGCCGCCGGATGCCGACCCACCAGGCCCGGGTGGACTTCACCCTGACCGGCCCCGGCACGTTCCTCGGCGGCTTCAACTCCCACATCCCGGGCAGTGTGCACAAGTCCGCCGTCGAGACCGAGGCCGGCGTCAACCGGGTCTTCGTCCGCGCCACCCGCGGCGCCGGCACGCTCACCCTGCGCGCTACGGCGTCCGGGCTGACCGCCGCGACCGCCACCGTCACGTCGACCGCCTTCACCACGACCGGCGGGCTCACCGTCCTCCGCTCCTGAACCCGAGGTTTTCCGGACGAACCCTATGGAGAAGAACATGAGTGGACAACGACGCCTGCTCGCCCTGGTCGCCGGTCTCGTGCTGGCCCTGCTGGGGTCCGCGGGAGTCCAGCTCGCCGCGGCTCCCGCCGCCCGGGCCTCCACCGGCCAGTTCCACGGCGTGAACTGGGCGGATCAGCGGGACAACTTCCTGTGGGACGAGAACGTCCCCATCGGACTGTCCAAATCGGACAATTACGCGACCACCTACACCAAGGCCACGGCGGTCCTGAAGGGATTCCAGGGCCTGGGCACCAACACCGTCCGGTTCGGCATCAACCCCCAGACCACCGCGTCGTCCTGGTGGGGAAGCCTCACCGCCGCCTACGACGCGGCGAGTGCCCTGGGCATGAACGTGATGATCGCGCCCTGGACACCACCGGACGGCAGCGGCCGGATCAACGGCGAGTCGGCCGCCTTCTACCGGATGTGGGACACCGTCATCGCCAAGTACGGCGGCAAGAGCAACTTTTACTTCGACATGATCAACGAGCCGTGGGGGTACGGCGCGACCGAGCTGACCAACCTGGCCGCCGACTGGCTGGCGCACTACCCCGCCATCCCGCGCGGGCGCATGGTGATCCCGGGGCTGTGGGCCGACCAGGACATCTGCACGGTCGGTGCCGACTCGCGCCTCAACGGCACCCTGCTGTCGATCCACCTGTACACCCTCGGCGGGGAGACGCACCCGACCGCCGCGGAGTGGGCCGCCACCTTCAGAAGCCGGTTGTGCGGCTACGCCGACCGGGCCGTGCTGAGCGAGTTCGGCGTCCCGATGAACACCGGCATCAACTACAACGGGCCGCGCGACGGTACCAACAACGTGTCCTACCTCTACGGTCTCACCGACACCGTCCGCAGTCTCGGCATGGGTTCGCTGCTGTGGACCGGGGTGAAGCAGGCCGACCAGACGGTGGGCCCCGGCCCCTGCTTCAACGCGTCCTGCGCGATCACGTCCCTCGCCGGCAGCGGAACCAATCTCTCGCTGACGGTGACCAACCAGTCCGGCCTCGACCGGTTCCGCTACGGCTGGGGACTGAACGACAACCCCGGTGGCGGTAGTGGCGGCAGCGGCGGGGTGCTGCGGGGCGCCGGATCCAACCGGTGCCTGGACGTGCCGGGCGTCAGCCAGGCCGATGGCACCCGGCTGCAGATCTGGGACTGCAACGGGGGCACCAATCAGCAGTGGGCGGCCTTGTCCAACGGCGCCTTGCAGGTCTACGGCAGCAAGTGCCTCGACGTGCCCGGACACGCCACCGCCTCGGGCACCCGGGTCCAGATCTACACCTGCAACGGCGGCGCCAACCAGCAATGGCGGCTCGGCTCCGACGGCACCGTCATCGGAGTCGAATCCGGGCTGTGCCTCGACGTCACCGGTGCCGCCACCGCCAACGCCACCCCCGTCGCCATCGCCACCTGCAACGGCGGCACCAACCAGAAGTGGACCCGTCAATAGCCCTCCCGGCATCCCGGCGGCGGGCGGCTTCGTCAAGACGTCCGCCGCCGTATCCCGGTCCTCGCGCACCAGCACCGATCAGTTGGGGAGTCCCCATGCGACCACACCACTCACCGCGCGGCCGGCACCTCCGGCGTCTGCTGGCCGGCGGCACAGCGAGCATCCTGATGACCGCCGCGGCCCTGCTGCCCGCCGCACCGGCCGGCGCCGCGACGTCCGCGTCCGTCACCGTCAACACCGCCGCCACCCTGGGCACGATCCCGGCGGCCGGGCACGGTCTCAACTTCGCGATCTACGACGGCCACATGAACGACGCCGCCATCCCCGGTCTGGTGAGCGGGGCCCGGTTCAGCGCCCTGCGGTACCCCGGCGGCTCCTACGCGGACGGATACCACTGGCAGACCCACACGATGGAGGACGGCGGGTACGTCGCCCCCAACACCGGCTTCGACACCTTCATGTCCACCGTGCGGACCGCGGGCGCCCAAGCCGTCGTCACCGCCAACTACGGCAGTGGCACCCCCGCCGAAGCGGCGGCCTGGGTCCGCTACGCCAACATCACCCACGGGTACGGCGTCAAGACCTGGGAAATCGGCAACGAGGTCTACGGCAACGGCTACTACGGCGCCAACTGGGAGCACGACACGCACGCGGACAAGAGCCCGAGGGCGTACGCGAACAACGTCCTGCAGTTCATCTCCGCGATGAAGGCCGTCGACAGCACCATCAAGATCGGCGTGGTGCTCACCACGCCGGGCGGCTGGCCCGACGGCATCGTCCACTCCGGGGACGCCATGGACTGGAACAACACCGTCATGTCCATCGTCCGGGACCAAGCGGACTTCGCCATCGTGCACTGGTACCCGGGCGCCGGGTCCGCCCGCGACGCGCTGAGCAAGCCGCGGCAGATCGCCTCGACCGTCGCCGCGGTCCGCACGGTGATCGGCAAGTACGCCGGGGCCAACGCCGGCCGGGTCGGCATCGCCGTCACCGAGACCAACCCCGGTTTCCAGCTCACCAGCGCCACCTCGGCCCTGTTCGCCACGGACTCCTACCTCACCTGGTGGGAAAACGGCGCGTTCAACCTGGACTGGTGGGACATGCACAACGGCTCGAACACCCCCGCCAGTCCCGCCGATGACGGCACCACCGACTACCACGACGAAGGCATCCTCTCCAGCGCCAGCACCACGGAACCACCGCTCAACACCCCGCTGCCGCCCTACTACGGGCTCGCCATGACCGGCCGCGCCGGGGCACCGGGCGACACCCTGCTCGCGACGTCTTCCAGCAACTCCCTCCTGGTCAGCCACGCCGTCAAGACGAGCACCGGGGTCAACGTCGTCCTGATCAACCAGGACCTCGGCAACTCGGCCACCGTGTCGCTGTCCTACAACGGCTACACGCCGAACGGCACCACCACGGTCGACCAGTGGAAGAAGGGGGACACCTCGATCAGCACCACGACGCAGGCATCGGCGAACTCGATCACCGTCGCGCCCTACTCCGTCACGGTCCTGCACACCGCCGGCGGCGGCGGGAGCAACCCGGCCGCCGGCGTGCTCAAGGGAGCCGGATCCGGCCGCTGCGTCGACGTGCCGGGGGCGGTCAGCACCAACGGCACCCAGGTGGCGTTGTGGGACTGCCACGGCGGTACCAACCAGCAGTGGACGTACACGTCCGGCCGGCAGCTGACCGTCTACGGAACGAAGTGCCTGGACGCCGCGGCCCAGGGCACGACCGCCGGCACCAAGGCGCAGATCTGGGACTGCACCGGCGCCGCGAACCAGCAGTGGAACCTCAACGCGGACGGCACCGTGACCGGCGTCCAGTCCGGGTTGTGCCTGGACGCCGCCGCGAACGGGACCGCCAACGGCACCCCGATCCAGTTGTGGACCTGCAACGGCGGCAGCAACCAGCGGTGGTCCCGGTGAGACGCGGCATCACCCGCGCCTTCGGCGTGGCGGTTGGCCTCGTCCTGGGTCTTGCCGTGCCTCCGGTGACGACCGCGGCAGCCGGCGTGACGACCTGGTGGTGGGTGGACTGCGCGTCCGCCGGCAACGGCAACGGCACGGCACAGTCCAGTCCCTGGAACACCCTGAGCTCGGTCAACGCCCACACCTTCAAAGCCGGTGACGGACTCGTCTTCGCCACCGGCACCAGCTGCCGCGGACAGCTGGCCCTGCGCGGGTCGGGCGCCAGTGGCAACCCCATCGTCATCGGGCAGTGGCGAAGCGGCCACGGGTCGGGCAAGCCGATCCTCGCCGGCGGCGGGGTCACGCCGGCCACCGTGTACCTGCACGACAACGAGTACGTGACCGTCGAGGATCTCGAAGTCACCAACAGCGGCGCGAGCGCGGGAGACCGGGCCGGCATCCTCGCCTACAACGACACCGGCAGCACCTTGCACGGCATCACCATCACCGCCAACACCGTCGACAACGTGAACGGCTACCGGTGGGGCTACTACGGCGTCAACGCCGGGATCGCCGTGGACATCGACGGCGGGCTCGCGAACCCCGGCGTCTACAGTGGCGTGACCATCTCGGACAACGCCGTGTGGAACGTCAACCGGGCCGGCGTCTGGGTGGGCAGCCTGGCGGAGAACGGCGCCATCTCCGCGCGCAGCACCGGCGTCACCATCTCGGGCAACCAGATGACCGACCTGGGTGCGGACGGCATCGTGACGCGCTACACCAGCGGCGCGCAGATACTCAACAACGTCGTCTACGACGCCGGCAGCTGGTCCGGGGGCGCGAACTCGGGCAGCCCGAGCTACTACAACCCCTATCCGGACGGTATCTGGCCGGTCAACAGCGACAACCCGGTCGTCCAGGGCAACGAGGTGTTCGGTTTCGTGTCGCAGGGCGCGGGTGACGGCGACGCCCTGGACTGCGACCTGCACACCACCAACTGCCTCATGCAGGACAACTACAGCCACGACAACGTCGACGGCCTCTGGATGGACTGCAGTGGTGCCGGGGGCCGAGGCGAAGTGTTCCGCTACAACATCTCGCAGAACGACGCCACCGCCCGCAACGGCATCTTCAACAACGGCTGCGGCGGGTCTCCGACTCCCGCCGTCTACAACAACACGGTGTACATCGGCTCCGGCAGCCCCAAGATCGACAGCGCGAACCGGGCGAACTGGGGCAGCGGGACGGCCTTCACCGACAACATCATCGACAACCAGGGCAACGGCGGCTTCGGCACCAGTGCCCGCTGGGATCACACCCTCTTCCACGGCTCGGGCAACCGGCCCGCCGACAACACGAACGCGGTCGTGGGTGACCCGAGGTTCGCGCACCCGAACGGCGCCGGCAACGGCCGCGGCACGGCGGCCGCCGCCTACGCCCTGTCCAGCGGCTCGGCGGCGATCGGCACCGCGGTGGCCATCGCCGGTGCTCCCGGGCGGGATTTCTCCGGCAACAGCGTCTGCGCCAGTCCTGACATCGGAGCCATGCAGAACCTGTGCGGTCCGGCGGGCCAGGTGAACAACCCGGGATTCGAGACGGGCAGCCTGAGTCCCTGGACCAACCTGGCCGGCGCCGGCGTGGTCGGCGACAACGCGCACACCGGCAGCTACGCCGTGCGGACCGGAAACGTCAACTCCGGTGTGTCGCAGACGGTTTACGGGCTCGCGTCCAACCGCACCTACACCCTCACCGGCTGGGTGAAGTCGAGCAACGGCAGCGACGCCGTCTACGTCGGCGTCAAGAACTACGGCGGCACGGAGACCAGCATCCCCGCCACCTCGAGCACCTACACGCGGATCAGCGTCACGTTCACCACGGGCTCGGGCAGCACCAGCGCAACCATCTACTGCTGGAAGAACGGGGGCAGCGCCGCAAGCTACTGCGACGACTTCTCCGTCAGTTGACGCACGACGAGCGAGGAGGCGTCATCGGATGCGTCGGCCAGAAGCCGGAAGACGATCGGTTCCCCGCAACTCGGCCCGCGGGCGCCGGTGCACTACGTGGGCGGCTCTGGTGCTCGCCGCCGCGGTCGCGGTGATCGTCGTCCACCAGACGTCGGCACCCCCGGCCGGCCAGGACCCCGCGGCGCCGCTGCCGGACGGCCCGGTGCTCACCGTCGGCACCGACCCGGTCGACTCACGCGAGTTCCTGCTGCAGATGGGCACGAACCGCGCTGAGGTCTTCCAGTACTTCTATGATCACTACGGAGTGCGGGACACCGCCGGCTTCTGGACCACGCCGCACGGCGAGACCACACCCCTGGCCATGCTCAAGCAACGCACCACGCAGCAGCTGGTCCGCCTCACCGTGCAGCTTCAGCTGGCCCGCGCCCGCAACCTGGTGGAGGACATCACCTACGGGGCACTGGTGGCCGGTATGCCAGAGGAGAACCAGCGCCGGACGGCCGCCGTAGCGCAGCACAGACCGGTGTACGGTCTGACGTCCTTCACCGAGGAAACGTACTTCAACCACGTCACCACCAACCTGGCGGTGGAACTCAAGCAGAGTACGGAACAAGGCATGAAGCCACCCCCGACCGCGGTGCTGCACCAGCTCTACGAACAGTTGCGCGAGCAGAACTTCTCCTGCCCGCCACCCGGCCGGCAACAGCACGGCGAGTCCTCGGCGAAATCGCAGTACTGCGCCGATGGTCAGCAGTATTTGCCGTTCGTCGCGGTCGAGCCCCAGGTGGTGCAACGTTGGAAGGACGACCAGTTCGAATCCCTGATAGCCGCGAACATCCGTGCGGCCCACGTGGAGATCAACCACATGGTGTTCGACAAGATCGAAGCGCAGTAAACCGTCCGCCAAGCTTGCCTCGACCATCAACGTGCCGACGAAAACCCCTGGTCAGACCCGTTCCCATCCTATGGTAGTCCTGCCGAGGGCACCCTCTTTGATCACGCGAGCCGGTTCCGGCCGGGGCCGGTGGTCCCGGAGGAGGTCCTCGCGAAGTCGGTGACCGCGTTGCTGGGGCCGGAACACGCCACTCCCGCTCAGGTCCGGGCCACGGCCGTCGAGGGCATCCAAGCCCTCGCCGACGGTCGCGCGACGGCCCTCGAGCTCATCGCCGCGCCCGCCAGGCCGGTCTCCGCCGTCTGAACACACTCCGGCGACCGGAAATTTTCGCCGCCGGCATCCGCTCGCTGCACCAGGTCAGCGCGCCGGGCTCGGTAAACGACCGCCCATCGGCCGATTGACGTCCGTGCCGCGGCCGGTAACGTGTGGGAGCGCTCCCACACGCCGGCGGCAGGAGTTTCCTCATGGGTGCTCAACGACGACACCACCTCAGGCCCGGAACGGCGAGCGGCTGTGTGCTGGCCGCGTTGCTGACCGCACAAGTCATCGCCGCGCCCCCGGCTTCCGCCGCCGGGCTCAGCCTGTCGGTGGGCGTGTCCGCCGCCCGGCACCCGATCAGCCCCGGCATCTACGGCCTCAACGGCGGCGATCCGGCGTTCAACGCCGAAATCGGCCAGACGGTGGCGCGCTGGGGCGGCAACGCCAGCAGCCGCTACAACTTCAAGAACCACACCTACAACACCGGCAGCGACTGGTACTTCGAAAACATCGTCGCCGACCAGGAACACTCCGTCGAGGGCATGGTCGGGTCCAACCTCGGCCGCGGCATCAAGCCGGTCGTCACCGTGCCCCTGAGCGGCTGGGTGGCCAAGGACTCGCCGTCGTCCCACCCGTTCGCCTGCGGGTTCCCGGCGACCCGGTTCCCGCAGCAGGACAGCTTCGACCAGTGGGATCCCCACTGCGGCAACGGAAAGCTCAACCAGGAGAACCTCACCGGCGTCCCCACCGACACCTCGGTCCCGGCGGACGCGGCGTTCGACGGCGAAATGGTTTCGCACCTGGTGGACCAGTTCGGCACCGCGGCCCAAGGTGGCGTGCCGATCTACGAACTCGACAACGAGCCGGTGCTCTGGTCCAGCACGCACCGGGACGTGCACCCCGATCCGGTCTCGGACGACGAACTGGGCGGCAAGGGCACCGCGGCCGCCGCGGCGATCAAGGCCGCCGACCCCAGCGCGGCTGTCCTCGGCCCGTCCGGGTGGGGATACTGCGAGTGGGTTGCGTCCGGAGTGGACGGTTGCGGGCCGGGTGCCGACTCGGCCGCGCACGGCGGGCTCAACCTCTCCCAGTGGTACCTCAAGAACATGAAGGACTACAGCGACGCCCACGGCGGCAAGCGCTTCCTCGACTACTTCGACCAGCACTTCTACCCCCAGATCAGCGGCGACAAGACGCCGGAAGCCAATGCGCTGCGGCTGCGGTCCATCCGGTCGCTGTGGGATCCGACCTACGTCGAGGAGTCCTGGATCGGCCCGAGCGGGGTCAACGCGCCGCCGCTGCAGTTCATCCGCACGATGAAGTCGTGGGTCGACCGGTACTACCCCGGGACCAAGACCGCCATCACCGAGTACAACTGGGGCGCGCTGGACGACATCAACGGCGCGCTGGCGGAGGCCGACATCCTGGGTGTCTTCGGCCGTGAGGGCCTCGACCTCGCCACGATGTGGGGCGAACCGAAGCCGACCGACCCGGGCGCGTACGCGTTCCGGATGTACCGCAACTACGACGGCGCGGGCAGCCGGTTCGGTGACGTCAGCGTGTCGGCGACCGCCGCCGATCAGGGTCAGCTGGCGGTGTATGCGGCGCAGCGGTCCTCCGACCAGGCGCTGACCGTCATGGTCGTCAACAAGACCGGCGGCGACCTGACCTCGCCGCTGTCGGTGGCCGGGTTCGACAACGCCGCTGCGGCACAGCGGTTCACCTACAGCCCGGCCAACCTGGGCGCCATCGTGCGCGGTGACGACCTCCCGGCGAGCAACGGCCACGTCGACGCGACCTACCCGGCGAACTCCATCACGCTGCTGGTCCTGCCGGCGGCCGGGTGCTCGGCAAGCCTGTCCGTCAACGGCGACTGGGGCACCGGACACGTCGCGACGGTGACCGTCACCAACGACCGCCGCACGGCGATCACCGGATGGCGGGTCAGCTGGACCTGGCCCGGCGACCAGCGGATCACCAACTCGTGGAACACCACGCTGAAGCAGAACGCCGCGAGCGTGGTCGCCTCCGATGCGGGGTGGAACGGCCCGATCGGCGCGGGCGGCAGCACGACCTTCGGGTTCCAGGCGACCGGGACGGCACCACCACCGAAGCTGACCTGCACGCCTGCCTGAGAAAGCTGCTTCCGCGCCGGTTCTGAAACCGCGCCTGCCGTTCTGCGGCGGCGAACGGGACCGATGCCGCTGCCCCGGCGGATGCCGACCCCGGGCCAGCGGTGGCGCTGCTGGAGCGGGAGGCCGGGTTGCGAACCGTCACTCCCGCTTCGCGGCGGGCTGGAGCTCAGTCTTGGGTGCGGAGTTCGGAATTGAGGCGCTGGGCTTCGTGGAGCTGGTCTTCGAGGCTGACGATGCGGCAGGCGGCGTCGATCGCGGTGCCGTGATCGACCAGTTCCCGCACGCGGGCGGCCAGCCGCAGCTGGTAGCGGGAGTAGCGGCGGTGCCCGCCGGCGGAGCGCTGCGGCGTGATCAGCCCGGCTTCGTCGAGGCTGCGCAGGAAACCCTGCGTGGTGCCGAGCATGTCCGCGGCCCGGCCCATGGTGTAGGCGGGGTAGTGCTCATCGTCGAACTTGTCGGCCGCATCCGGCGCGGCCGGTCCTGCTTGGTCAGGAATCATTCCACCTCCGCATCACAAAGGACCCCGGATGCCGCGCACGGCATCCGGGGTCCTCAAAGGGTTGGGTTTCACCATTGTCAACCGGCGCGACCGCCGGCTTCCTGCACCCGCGACCGGTCGAAAACCGGAACTCGCGGGGATCGCTCATTCGTGACCGAGCACCACCTCCGAACTCGATGGGACTACGGCACCCGCGCGGCGCTACTTCCCGGCCGCTGCGGGCGATCCAATGATGCTCCCGATCCCTTCTCTCCTGTGTTTTCCACTTACCGGGTACTGCTGTTACTTCGGGTACTGCTACTTCAGGTACTGCCACTGCACTTGCTGCTGCGGACGTCACTGCCGGAACCCTTCCACTGATCGGTCCCAGCACGCTGACGCCGCTGGTCACTGCCCGGAGCCCCGTTCACTGATCGGCTCCGGCCACCTGACCGGTCCTGCCACTGCACTCAACACTTACAACACTCAACACTTGCAACTTGCACTGCACTTGCACGGAAAACAACTACGGGTACTACTCCGGTCACCAGCCGAAACCTTGTTCCGTGATCGGCTCCGCGCTGCCTGACCGTCTTGTCTCACCTCGCGGGTAGTTACGTCCTCTCCCGCGCCTGCTTGACGTTGTCTCTCTCGCTACGAGAAGAACACTACACACACCCGCCATCCAATGTCTACTCCAGTCGGCATAGATTTTCTGTGGCGTGTCGGTCTGACGGTGAGGAAGAGGGGTGCGACCGTGAGTGACGAGGCCGTCCGGGAGCCGCTCGAGGAGCGTTACGGCCTGACCGAGGTCGCCGACCTCGGGGAGTACGCCGTGGCGCTGACGCGGTTGCTGGAGCGGGGACGGCGGGAGCGGTGCGTGGCGGTGTTGTCGGAGGCCGAGGCCTACGCGGCGGCGGAGCTGCTCGGGCAGTTCGCGCAGCTCGACCCGCACGCCGCGCTGAACCAGCTGGCCGGGTCGCTGGCGAGCCGGCTCTACAGCCGCCTCGGCGCGTGACTCCGATCCCGCGCCCGGCGGGACGCTCACTCCGGCGGTGCACGGAACCCCTCGGCGGCCGGGCCGAGTCATGCGGGTGATCGCGGATGAAGAGGCGCCTCAGGAACAGGCCACCGCGGCGCACGGCACTGCGTCGCTCCCGCCGCAAGACACTTCCGCCCAGACCGTCTTGCTGCCGGCCGGGTGCTCGGCCACGCCCCAGGAGCAGGCGAGCTTGTCCACGATGTGCATGCCGCGGCCACCAGGGCGCTCGAGCGACGGCACGGTGAGCTGGGGGTGGTCCGGGCAGTTGTCGTCGACTTCGATCCGGACCCGGCACGGGCTCGGCGTGTGGCTCATCCGGACCTGCAGCGGGCCCTCGCCGTGGTCGTAGGCGTTGGTCACCAGCTCCGTGGCCACCAGCAGCACATCGCCCAGGTGGGCGTCAGCCACCCGGGCCAGTGCCCGGGACGCCCAGCGACGGATCTCGACCAGCGCCGGGGCGGTGGTCCCGCGCAGGTCCATCGACCACGACGGCGGGGCCGGGGCCGGCTCGTTGCTCGGCTCGGGCATGACGAATCAACCCTTCCAGGCTCTCCGCCCTCGCTGCTGAAGACGTCCGCTCTCTGGCGGTACCCCGGCCGTGGCCGGGCCAACCCTCGCTCGGCGGGCAGACCGTCACCACCTCGCCGTTCGAGGCCGCCATCACCAGATTCCCCCGGGTGGCGTAGCGCAGACCCCCAATCGGTGTGATTTCCCGGACGGCTGGGTAGTCAGCTGCCCAGGTCTGGGGTTTCGGCGCGCAGGAGCCCAGGACCAGGCTTCGCCGGTCCAGACCCGAGGCCGGCGAAGCCGCCCCGGCACTCCTGGAGACGCCCGATCGACCGGACGGCAACCCGTGCAGCTTCACGGCGAAGAAGAGGACCGAGATGCGCCCGGACCTTCTCGCGGGTTCTGCGTTCCGGGGCGGGTTCGGGTCGGTGCCGGGGCGGCCGGGTGATCGCTGAAAGCGTTTTCAGTACAGACGACCCGCTTGGCCCACTCGGGGTGCCGCCGGCCGGTGCTACCGTCGCCTCACCGGAGATCCCGCTCCCGGTGGGAGCGCTCTCGGATCCGGTGTCCGGCACATTCTTGCCCGCAAGGAGGCGTGCAAATGGGTTCGCACGGAAGCATTCCCCGCAAGAAAGCGCTTGCAGTGAGCGCCGCGCTCGTCACGATCGCCGCGTTGGCACCGCCATCCGCCGCCGCCGCGGCCACCACCCTCTACGTGGCGCCCAACGGCAAGGACTCCGCCGCCGGTACGCAGGCGGATCCGACCACCCTGCCCGCGGCGCTCACGCGGATCGGTTCCGGTGGCACCATTTCGCTGCGTGGCGGCACCTACTCCTACGCCCAGACCGTCACCATCGCGCCGGGCAACAGCGGCACCTCCAGCGCGCGCAAGACGCTCTCGGCGTATCCGGGCGAGACGCCCGTGCTGAACTTCTCGGCCATGAAAGAAGATCCGGCCAACCGCGGGCTCGCCGTCAACGGCTCCTACTGGCGCGTCGCCGGCATCGTCGTCGAACGGGCCGGGGACAACGGGATCTTCGTCGGCGGGAGCAACAACGTCCTCGAACGCGTCGTCACCCGCTTCAACCACGATTCCGGGCTGCAGATCTCCCGGATGGCGTCGAGCACGCCGAAGGACCAGTGGCCGTCGAACAACCTCGTCGTCAGCTCGGAATCGCACGACAACGCCGATTCCGACGGCGAGGACGCCGACGGGTTCGCCGCGAAACTCACCGCCGGCCCCGGCAACGTCTTCCGCTACGACGTCTCCCACAACAACATCGACGACGGCTGGGACCTCTACACCAAGACCGACACCGGCCCGATCGGCCCGGTGACCATCGAGGACTCCCTGTCCTACGCCAACGGCACCCTCAGCAACGGCACGGTCAACAAGAACGGCGACCGCAACGGCTTCAAGCTCGGCGGCGACAAGATCGCGGTCAACCACATCGTCCGGCGCGACATCGCCTACCGCAACGGCCACCACGGGTTCACCTACAACAGCAACCCCGGCTCGATGTCCGTTTCGGACAACGTCGGCATCGACAACGCCGAACGCAACTTCTCCTTCGACACCGGCACTTCGGTGTTCCGCAACGACACTTCGTGCCGCTTCCTCAGCGGCGGCTCGAACGACAAGACCGTCGGCAGCGTCGACAGTTCCGACCAGTTCTGGACCGGCAAGAACGGCTCCCGGTGCTCGTCCTACGCCGGCACGATGAAGTGGTCCTTCGCCTCCGACGGCCGGCTCGTGGTCACCTTCGGCTGAGCAACCGCCGTGCGTGGGCCGGCCGGGTGAACCGGCTCACGCACGGCGTGGCGAACCTGTTGAAATGCTGTGAACCGGACAGACCTGGCACTCCCCGCGGCACCCGTGCGTTCTCCGGGTAGCAGAAACGGAGGGATCATGGGTGCACTAGGGACACTGCTCGGGTTCGCGCTCAGCCTGTACCTGCTCGTGCTGATCGCGCGGATGGTGCTGGACTGGGTCGCGGTGGTGGCGAGCACCCCGCCGTGGGCGCGGCGCGCCCGGGGCCTGGCCTACGCCGCGACCGAGCCGGTGATCGGGCCGGTGCGGCGGGTCGTGCGGCCGGTGCGGATCGGCGGGCTCTCGCTCGATCTGGCCTTCACGCTGGTGTTCGTCGGCGTGATCGTGCTGCGGAGCATCGTGTACGTCCTCTAACGCGTGCCGCGGAAACTGGCGGACAGCCGGTCGACGCTGCGCTCGAGTTCGGCGCGCAGCCCCCGCAGGTCGACGCCGTCGGGGTCGATCAGGGCCTGCATCGAGATCCCGCGCAGCTGGGCCAGCATCGCCGAAGCGTAGGAATCGGGGTCGCGGACACCGGTGATGGACCCGTCCGCGACCCCGCTGGCCACGGTCTGGGCGATGGCGAACCGGAACCGGCGGTCGGCCTCCGTCAGCGCGCCGCGCAGGGCCGAGTACTCCGCCGCCGCGTCGCCCCACAGGGCCAGGAACGCGTGGTTGAGCGTCGGCATCGTGCGGATCAGCTCGAAGATGATGTCCAGCAGCGCGCGCAGCATGTCCATCGGCGTTGCGTTCGCCGACCCGGTGCGGGCCGCGACCGCCTCGCTGTAGGCGTCGGTGAACTCCTCGACGGCGTACTCGACGAGCCGCTGCCCGAGCCCGTCCTTGTCGCCGAAGTGCTGGAAGACGACCGACCGCGCGTAGCCGGAGCGGGCGCAGACGCCGCCGATCTTCAACCTGCCGAAGCCCTCTTCGGCGATCAGGTGAGCAGCGGCATCCAGGATGCGTGCCTCGACGGCGCCCTCGCCGTCCTCCTGGATCCGGCCTTCGGCGGCGCGGTCCACCCGGGTCATGTTAGCGACTGCAACCGCGGCGCACTGGCCGAGCCGTCAGCGGACGGTGCGAGGACCGTCAGCGGCCGCCCGCAATCTCGGCGTCGGCACTCACCGACCCGAGAGGAACCCTCCGATGACCGCCAAGACCGTGCTCGTTTCCGGGGCAGGCATCGCCGGCCCGTCCGCCGCCCACTGGCTGCACCGCGGCGGCTACCAGGTGACCGTCGTCGAGTCCGCGCCCGGTCTGCGCCCCGGCGGCCAGGCCGTCGACTTCCGCGGCGAGCAGGTGAAACTGCTGGCCGCGATGGGCGTTCTCGACGAGATCCGCCGGTACGAGACGGCGATGGGCGACCAGACCGTGCTCGGTCTCGACGGCCGTCCGGTGCTGACCGTGCCCGGCGCCGCCTGGAGCGGCGAGGTCGAGATCCTGCGGGGCGATCTCGCGCGGATCCTCTACGAAAACACCGCGGACCACACCGAATACGTCTTCGGTGACCGCGTCACGAGCCTCACCGAGACCGCGGACGGCGTCGAAGTCACCTTCCGCCACGGCGCACCGCGCACGTTCGACCTGGTCGTCGGGGCCGACGGTGTGCACTCCGGCGTGCGGGCCGCCGCCTTCGGGCCGGAGCCGGACTTCCGGACGGACCTCGGCTTCGGCATCGCCGGCTACACCGTGCCCAACCACCTCGGGCTCGACCACACCAGCATCATGTACAACGAGCCCGGCCGCGGCCTCATGGTGGGCAGCCACCGCCTGCCGGACCGGCTGCACGTCGGCCTGGTCTTCGCCGCCGACGGCGTCGAGTTCCACCGCCGCACCGCCGTCGAACAGAGCAGGCTGATCACGCAGTTGTTCGCGGACACCGGCTGGGAGACACCGAAGCTGCTCGAGGCGCTGCCCGCGGCCGACGACCTGTACGTCGATTCGATCAGCCAGATCCACCTCGACCGCTGGTCGAAGGGGCGGGTCGTGCTCCTGGGCGACGCCGCCTGGTGCGCCGGGCCGGGCGGGTCCGGCACCGGGCTCGCGATGATGGGCGCCCAGGTGCTGGCCGGCGAGCTCGCGGCGGCCGGCGGCGACCACGTGACGGCGTTCGCGAAGTACGAGCAGCGGCTGCGCAAGCCGGCCACGGTGGGGCAGAAGAACGGCAAGGGCGCCGGCAACTTCCTCGCGCCGCGCACGGCGGCGAAGATCCGCAGCCGCAACCGCGCCTACCGGATGCTGAGCACGCGGCTGCTCGGCGGCATCTTCCTCAAGATGACCGATCGGGCGGCCAACGCGCTCGAATACCGGGAATACCCGGCGCTCACCGCCGCGTGGTTCCGCTCATCGGGGGATCCGGCTGGCGGCCGGGCGTGAGGTAGGTCACTCTCGACGCCATGTCCCCACCTCGGGCCGCCGATGCTCCGGTCCGGACAGCGCTCGCCGGACTTGCGGTGCTCGCCCTCGGCGTGCTCACGGCGTTGAACGCGCGGTCCCTGCCGGTGCTCGGCGACGGGACGACCTACTCGGCCGAGTTCACCGAAGCGGCCGGGCTGAGCGAGGGCAACGACGTCCGCGTCGCCGGCGTCGAGGTCGGGCGGGTGTCGGACGTGCGGCTGCGCGGCGACCACGTGCTGGTTTCGTTCCGGGCCAAGGGTGCCTGGCTGGGCGACGCGACGAGCGCGGCGATCCGGCTGAAGACCGTGCTGGGCCAGAAGTACCTCGCCCTCGACCCGCAGGGCGAGGGCACGCTCGACCCGGGGCAGCCCATCCCGCGGTCCCGCACCACGGTGCCCTACGACATCCTCGCGGCGTTCGGCACCCTGTCGTCCACAGTGGACCATATTGATACCGCGCGGCTGGCGAAGAGCTTCGACACGCTGTCGGCGACGCTGGCGAACACGCCGCAGAGCGTCCGCGCCGCGCTCACCGGGCTCTCGCGGCTGTCGGACACGCTCGCTTCACGCGACAGCCAGCTCGCCAGGCTGCTGGGTAACACGCGGGTGGTGTCGCAGACGCTCGTCGACCGCGACGCGGCGGTGCGCCGCCTCCTGGATGACGGAAACCAGCTGCTCGCGGAGGTGTCCAACCGCGAGGCGGCGATCAGCACCCTGCTCGACGGCTCGCGGCAGCTCGCGACGGAGTTGTCCGGGCTGATCAACGAATCCCGCGTCGGCCCGCTGCTCACCCAGCTCGACCAGCTGACGTCGATGCTGCAGCGCAACCAGGACGCACTGGCTGCCGGGATCCGCGCCTTCGCGCCGTTCGTCCGGCTGGGGACCAACCTCGCCGGGAGCGGCCGGTGGATCGACGGCTACCTGTGCGGGCTGGTGCTGCCGTCCTTCGGGCCGGTGAACGAAGAAGGCTGCCACGGTTAGGGTTTCGGTTTCGCCGATCGGAGGTCGGCGAAACCGGTTTCCACAAGCGGGGCTCGCTGTGGACAAGTTGGGCGCCTCATGGCTGTTCCGGCGATTCCGTCGGTGGGCGCCGATAGACTGGACTTGGGCACGCCCCCCTGGGAGGGCCACGGCTCCGGCAAAGTCTTTGTGCTGGTCAGGTGGGTATTCCGAGCAGGGTGAGGGCTCGGGTGGTGTTGCGGGCGGTGTGGCGGAGTGCTTGGGCGATGTTGGTGTGTCCGGCTTGTCGGTGTGTGCTGGTGGCGAGGTTGCGGAGGCTGGCCATGACGCGGGGTGCGGTTCCTGTGCGGGTTCGGGATTGGTCTTCTTTGTCGGTGACGTCGCGGACCCAGTGGAGTTTGTTTTCGATGTGCCAGTGGCTGCGGACGTAGCCTCCGATGTGGGCGGGGTGGGCGTAGCGGCCGGTGAGGCTGGTGAGGCCGAGAGCGGCGTGGGCGGAGCGTTTCTGGCTGGTGTGGTGGGTGGTGTAGCGCTCGATGAGGAACGCGTGCGTGGCGTGGGGGAAGTCGATGGCCGGGTAGCCGAGGAAATCGCCCAGGGGTGCGAGCTGGACGGTGCGGCGTTCGCTGCGGCCGTGCCCGCTGCCGCTGGTGATGTGGGCGGGGATTTCGTGCCAGGGCAGGGTGTCGAGCAGGCCGTGGAGCCGGTGTTGGTTCTCCTTGACGGTGAACACGTAGTATGCGCCGCGTTGATGCAGGTAGCGGGCGTGTTCGACGGTGGTGTGCAGGGCGTCGGCGGTGACCACCCGCCCGGTCAGGTCGATGGTGTCCAGCAGCGGTTGGAACCAGGTGATTTCGCTGCTGCCGACCGGGACCTGGCGTTGACCGAGCACTGTTGCCGTGTTGTGGGTGATCGCGGCAAGCAGGTGCACCCCGGCACCGCCGGTGCGGGCGAACGTGCCGCGCAAGGATTTGCCGTCCACCGCGATCGCCGCTGGTGGGGTCTCGGCCGGGTCGGTGGTGCTGGTGTCGCGGTGGGCGAGCCAGCTGCTGATCACGTCGTCGAGGATGTCGCCGTCGACCCGGCCGGCCACGCGCCGCACGGTGGCCTCATCGGGTGCTGCATACCGGGCATGGCGGGGGTCGAATCGTGCGCCCAGCGCGGCCAGCACCGACTGTGGGGCGTCGGCGGCCCATTCGCCGATCGCGGTGAACGACTGGGCTCCGGCCACCACGGCTGCGGCGGCGAGCGCCAGGATCGACCCGATCGAATGTCGCACACCCCGTCGATCTCGTGGATCAGGGAT

Protein sequences of DBSCAN-SWA_4

>NC_017186|8559516:8633698|8585060_8585630_-|WP_071831756.1|DBSCAN-SWA
MSHVSNAAEAMAAAARTITDDQLANKTPCTEYDVRALVNHLLFWGPSLAGAGRKESVPQPAAAESDVDLAAGDWRGRLLALLDDITSSWAQPSAWEGETSMGTPHTLPAPVMGDMIVGELAVHGWDLAVATGQRLELPADLLAHLHDTVVAGVEQGREMGMYGPEVAVPADAPTLDRIIGLTGRDPAWT
>NC_017186|8559516:8633698|8589795_8590089_+|WP_013229557.1|DBSCAN-SWA
MHNEQPVELAPRSVAQLTQDPAWTVTRTGTTGQWLTAERVLERNGHRRLVGLTPIQPGVVALILWDDGEVVEHLRGTEAEACTTAHRWVAEFLAGTR
>NC_017186|8559516:8633698|8591855_8592236_+|WP_013229559.1|DBSCAN-SWA
MTSGRTQTQQPLTGAPRTKYHGQCANFPYQATTSTENARRRFRLGRGNRVEAPDRLALTRMNSPRAGYAADMTTSPFEPDPKLGEQDIAAADPGQGAPNTAEGFGAGETGPDVIIPEDAGTEEDPR
>NC_017186|8559516:8633698|8576282_8577101_+|WP_013229545.1|DBSCAN-SWA
MKAARGSVVSKKGTPWGTIIAVVAIVALAASVIIYYMVQSAPKRAQADREAAAASFAPTASEPDPSKRIPGVVTATYTGSVHVLPTERVAYDKTPPFGGPHDQTWATCTGIVYPTAVRTENMVHALEHGAVWIAYNPQQITGDALNMLSVRAKGKPYTMLSPYPGLDKPISLQSWGHQLKVDDANDARIDEFIAALRSNPNGVYPEVGASCDAVPGQFDPDNPPPFNPAKPGPDAKPMDYKGSTAAQGEQGMPQSAPASAPASAPASAPTTK
>NC_017186|8559516:8633698|8579293_8579713_-|WP_013229549.1|DBSCAN-SWA
MSADPITEDVVALLGRIVDRFVESYEAAAAAQGLTTVQAKVLVALDEPLPMHRIAEKLKSERSNVTGIIDRLEARGLVERRPGERDRRIKNIVATPAGAELARNFRRALGFAAEPLAALVPADRVRLRDLLARMVDAEA
>NC_017186|8559516:8633698|8559516_8561490_+|WP_013229532.1|protease|DBSCAN-SWA
MRPSTPKTLALLAAVAVLTGLGTGTAAAEPLTRGWPAPIDAAHWENQDHMTWSDYRKVPGTNWADPALKPTQRTFKGAVVLADYPDQDFVVTKPANSTIFGNPAPTAANIPRANVAQYYQDFLNKPEALNNGHTINEYWMEDSGGRFGVQLTAFGPYRMPGKSYEYGMEFQPSACPPGANCARDIRKDAGDAWRADVGDTAKQFDFVFYLSAGQDESSTWQEFGEMKFGTKENVPDSFGPPNHDLPNYAATRYVPWTSWASAASIWPNAQNGSSVQAESSGQSTYAHEFSHILGIGDNYNNPFGVPPSRSYSGPWDMLSRGTFNGPGGPHTRWQIPATQGSSMGAQHQLRNKLKLGIVDSADVLQLDRTELAASGPVSARLTAREAEAQPGAFAGLNIKLTGGDKAPKCDRSKDPFCDGGGYDNYTVEVVDRMGSDSFAPDSGVLITKTKNQDNAPFDWVIDANPQDIGITDYTKPDGTPVKITVGDYRQLNDALFKAGTEAASPYEYTDEANRLRFLITDVARDRHGILSYTVTVASLDGSGGQAREAALTPALPAIARGGLATCEFGLLNTGSARGAKAPYDTDTYRLSVSTDTRGWEVRLPNELATAKFGGFAKVAAYAKRGQGGDLAARVKLTATSVSDPSKTATASCTAFGF
>NC_017186|8559516:8633698|8608435_8609887_+|WP_013229569.1|DBSCAN-SWA
MPKHRKLFRSWAAVSALLAAVSVIGAGVAHADSTGALRGVASGRCLDVTGRSQADGALMQVWDCNGGTNQQWTLTALNQLTVYGTKCLDVPGHATAAGTRVQIWSCNGGTNQQWRVNADGTVTGVESGLCLDVSGGGASANSTPVVLWTCNGQSNQQWTGLTPTGPGGGNLPSSFRWTDQGPLISAKPVSGHNIVSVKDPSIVRYNGQWLVYATTADTSGAWSVEYTHFTDFSQAASASQYHLSDNPNLGHRYMAAPQVFYFAPQNKWYLVFQQGPPAFSTNTDPTQPQNWSTPTNFFASTPPVVDQHGGGWLDFFVTCDTANCYLFYANDAGDIFRSQTTVANFPNGFGNTAVVLHDDNRGNLFEATAVYKVKGSSTYLMLVEGWDSVGHRVYRAWTAPSLSGSWTQIANPFAGLANVTFPSGQWTNDVSHGELIRTGYDQTMEIDPCHLQLLYQGVNPNSTNVPYSQLPYQLGLLTQTNPC
>NC_017186|8559516:8633698|8632588_8633698_-|WP_080582981.1|transposase|DBSCAN-SWA
MPDPRDRRGVRHSIGSILALAAAAVVAGAQSFTAIGEWAADAPQSVLAALGARFDPRHARYAAPDEATVRRVAGRVDGDILDDVISSWLAHRDTSTTDPAETPPAAIAVDGKSLRGTFARTGGAGVHLLAAITHNTATVLGQRQVPVGSSEITWFQPLLDTIDLTGRVVTADALHTTVEHARYLHQRGAYYVFTVKENQHRLHGLLDTLPWHEIPAHITSGSGHGRSERRTVQLAPLGDFLGYPAIDFPHATHAFLIERYTTHHTSQKRSAHAALGLTSLTGRYAHPAHIGGYVRSHWHIENKLHWVRDVTDKEDQSRTRTGTAPRVMASLRNLATSTHRQAGHTNIAQALRHTARNTTRALTLLGIPT
>NC_017186|8559516:8633698|8605620_8607201_-|WP_013229568.1|DBSCAN-SWA
MRKFWRSAFSAVLAAAAVPIALLSVQQPAQALENNLARTPQLGWNDWNSFGCNVNETLVRQTADVMVSSGMAAAGYQYVNIDDCWSEWNRDSSGNLVPDHTKFPSGMKALADYVHGKGLKLGIYSSAGTTTCQGYPASLGNEQRDANLWASWGIDYLKYDNCGDHQGRSGQDRYVAMRDALAKSGRPILFAICNWGGDSVNQWGPATGNSWRTTWDIQGNWGSVLGILDAQPGWAGLAKPGAWNDPDMLEVGNGLSDTEARAHFSLWALLNAPLLAGNDLRTMSAATRSILTNTEVIGVNQDWGGRQGNRIADYGDTEVWTKPMANGSMAVVLLNRGSGTSTISTSASQIGLGSASSYSVRDLWAHSTGTTSGAISASVPGHGAAMYVVTGGGVANPGTFALRGQGSGRCLDITGASQANGTPAEIWDCHGGANQAFTSTAAGELRVYGNTKCLDVSGNATANGTAVAIWDCTGGGNQQFRLNGDGSITAVGANKCLDVNGAATANGSKVQIWDCSGGSNQKWAKA
>NC_017186|8559516:8633698|8584127_8584532_-|WP_141748543.1|transposase|DBSCAN-SWA
MVVDHASSACSGCGGGLRRTDRAGVIRRQVVDLPPVRPSVTEHRLHRLRCGGCRQVTTATGPAEATTHDQSPAEDLRWLANPARRPRLATRPRLHLHRPQKRTPHHRRTPRRHHRKPLATNNNRNGLNSYVAPP
>NC_017186|8559516:8633698|8566892_8567123_-|WP_013229538.1|DBSCAN-SWA
MKSGIHPEYVVTEVNCDCGNSFTTRSTKTNGSIHVEICSNCHPFYTGKQKIMDTGGRVARFEARYGKRQKKDADAK
>NC_017186|8559516:8633698|8585784_8586438_+|WP_013229555.1|DBSCAN-SWA
MERYWEARWDYAEPYRQKIVPYPNVHLSFSGGRADVNGVRSGYQLKVLEGRDHVFGVAFRPGCFRPFLGASVSTITDRVIPVTAVFGPDLPTTLDVPTVDAFLLKHLPDDDPRVRQAVAAVELIANDKAMTRVERLADELGLSMRGLQRLFAEHVGIGPKWVIRRYRLHEVTARMAAGGAIDWAALAADLGYADQGHFIRDFKSMFGEPPTWYAQRY
>NC_017186|8559516:8633698|8626434_8626695_+|WP_013229579.1|DBSCAN-SWA
MSDEAVREPLEERYGLTEVADLGEYAVALTRLLERGRRERCVAVLSEAEAYAAAELLGQFAQLDPHAALNQLAGSLASRLYSRLGA
>NC_017186|8559516:8633698|8616561_8618031_+|WP_013229573.1|DBSCAN-SWA
MEKNMSGQRRLLALVAGLVLALLGSAGVQLAAAPAARASTGQFHGVNWADQRDNFLWDENVPIGLSKSDNYATTYTKATAVLKGFQGLGTNTVRFGINPQTTASSWWGSLTAAYDAASALGMNVMIAPWTPPDGSGRINGESAAFYRMWDTVIAKYGGKSNFYFDMINEPWGYGATELTNLAADWLAHYPAIPRGRMVIPGLWADQDICTVGADSRLNGTLLSIHLYTLGGETHPTAAEWAATFRSRLCGYADRAVLSEFGVPMNTGINYNGPRDGTNNVSYLYGLTDTVRSLGMGSLLWTGVKQADQTVGPGPCFNASCAITSLAGSGTNLSLTVTNQSGLDRFRYGWGLNDNPGGGSGGSGGVLRGAGSNRCLDVPGVSQADGTRLQIWDCNGGTNQQWAALSNGALQVYGSKCLDVPGHATASGTRVQIYTCNGGANQQWRLGSDGTVIGVESGLCLDVTGAATANATPVAIATCNGGTNQKWTRQ
>NC_017186|8559516:8633698|8587038_8587404_-|WP_013229556.1|DBSCAN-SWA
MTSTETDILTTVLDRWKSAVDAHDPKRVATCFTGDAIFQGLHPDSVGPDSVAAYYHGQPIGMTADYTVLQIRVLADDLVLGYLSVDFGFTDRPVLPVYLGVILRRTGDTWLISHYQVSRLD
>NC_017186|8559516:8633698|8590133_8591753_-|WP_013229558.1|DBSCAN-SWA
MLVAAGGLALAATVVAGAPAQGMGQHGAGRGLALTGVPANAKVAGLTVANALSPELAGWVAAQGSNRLENPVADIPFFGYRGDGPLLPAPGDLPAAGHLVEASKTEPDKNTYLVLHGQRGADPHYDYGTHFVFQGHEAGATGFITRVNLDADTAHRVTLLATATTDGKPLPNFDGSTWDPWARRLLFTAELGAGGGVWQSTLDGSRTEDISGALGRGGYEGIQNDSAGNLWVVEDSGGATVPGTNAKLPNSFVYRYVPGDRGDLTQGKLQVLQVFSRRTGAPIAFQPIDAAHPQGNAFSDDTKDLHTYGLSFGTKWVTIHDTATDPASAGFDANALAKAAGATPFKRPENGQFRPGSGFREFYFDETGDTNATSTANDGYGGWGAVLKLSQADPKADTGTLSLVYNGDKEHTGLDNVTFLDNDHVAFVEDAGDSLHTQRGLLDSAYLFDLRADYAHGAQPVRFLAEGRDPSATLDSALSGRTGFQNDGDNEITGIHASNGDPSPQGVLGAQRPTPFGGGWRLFWTQQHGDNVLWEITRR
>NC_017186|8559516:8633698|8579819_8580656_+|WP_013229550.1|DBSCAN-SWA
MSNDRVALITGTSSGIGLATAVLAARRGFRTVATLRDTGRADRLREAAADAGVELDVRPLDVTDAHSVSAAVAGVLADYGRLDVLVNNAGAGHIGTIEQEPVSAVRETMEVNFFGVAETTKAAMPALRASGGRLITVTSVGGVIGQPFNEAYCAAKFAVEGMMEALAPVAAAQGVTVCVIEPGAVATEFVNNVGVDERLFAEAGPYAESLQKYIANVTQSFQSAQTADEVAEVILGAMTADAPAFRIQTSKWAEEFAALKFADLDGSAVQRLTGGWLA
>NC_017186|8559516:8633698|8614118_8616536_+|WP_013229572.1|DBSCAN-SWA
MVYDLNPDWRFVQADVPGANATTFDDSSWTTVSVPHTYNDVDSFDNWITSSGESAVAMQITWYRKHFTMPAGLAGMKVFLEFERVRQAATVYVNGVQVGLCEFGVSPFGFDITDRIRFGADNVIAVKADNTKWRPEQAGGVGFQWDTRDFYPEYGGLTHNVRMHVLPRTYFTLPLSMNLGTTGTYVFPSAFNIPGATAAITAQAQVRNEDSAARTVTVSANLIDAGGALHATIAGSAVSVAPGETRVVTLSQRIPGLRFWSPASPSLYTVEMVLSIDGAVVDAYPVVTGFRKTAFQGGTTAGGVYLNDQYVYLTGYAVRTTNEWAVIGGAVPEWLTGLDGQLIRDSHANLIRWMHVSAPPNQIRMTDKYGIVSVQPAGDKESDVTGRQWDQRVEQMRASMVYFRNSPSILFWEAGNNWITAAHMSQMLDLRRTWDPAGGRAIGCRAISDSSAYGGTAAVDAAEYVGTMLNRHYSVYARDRKPVIECEYTRDEAPRRVWDNYSPPDFGYRTGPDVTYHWTSEDFAATVAASSRYEFWSQRIQGPGDRRYAGAAALIWADSNQHGRQYNWECARLSGRVDAVRIPKESLHSYRVMQNPAADIHVIGHWTYPSGTRKTIHVLASAAVHEVRLLVNGTQVGSNSSPAYDFLYSFPDVAWQSGTITAVGYTTGGTEVVRASKTTTGAAVALKLTPYTAPGGLRADGSDVAFFDVEAVDSAGRRMPTHQARVDFTLTGPGTFLGGFNSHIPGSVHKSAVETEAGVNRVFVRATRGAGTLTLRATASGLTAATATVTSTAFTTTGGLTVLRS
>NC_017186|8559516:8633698|8569719_8570604_-|WP_013229540.1|DBSCAN-SWA
MTGFRITVPASTANLGPGFDAFGMALSLYDVVEVRVTDAGLKVEVTDAGAGGVADVPTDETHLVVRAIHATCAHLGVEPPGLHLRCFNAIPHARGLGSSAAAVVSGVAAGYALAGRELDAFEALQLAAGFEGHADNAAASLLGGLVLAWCDGGRFHAERLTPHTSIRPVVAVPSVRSATATTRGLLPATVPHADAAHNAGRAALAVHALTTQPALLLPATEDRLHQSYRAPAYPASTELVATLRAHGVAAAISGAGPTVLALTTTGILPPGVGVDDFDVLELPVDLAGVQVAAQ
>NC_017186|8559516:8633698|8572990_8574421_-|WP_013229543.1|DBSCAN-SWA
MAHPAGPRHADVYTHADTSGHQPSGVEELDKLPAKVWPRNTFRAADGVVRIAGVDVRELAEQHGTPLFVVDEADFKSRCADYAEAFDDPSLVHYASKAFLSIEIARWVAEQGLSLDVCSGGELAVAQRADFPAERITFHGNNKSPAELEAAVVAGVGTVVLDSYFEIARLADIAARHDVVQSVLIRVTVGVEAHTHEFIATAHEDQKFGFSLASGDAAEAVRRVLNARSLKLVGLHSHIGSQIFDADGFEVAARRVVGLLADLAKEHGPELLDQLSLVDLGGGFGIAYTEKDNPPPPAQMITQIREIVRKECAYAGLPVPRIAGEPGRAIAGPGTITLYEVGTIKDVSLGDESARRYVSVDGGMSDNIRTALYDAVYDVRLVSRSAGDNEQPVPAVLSRVVGKHCESGDIVVRDCWLPDTLAPGDLLAVAATGAYCYSMASTYNRMPRPAVVAVRNGSSRLLLRRETTDDMLRLEV
>NC_017186|8559516:8633698|8625365_8625698_-|WP_013229578.1|DBSCAN-SWA
MIPDQAGPAAPDAADKFDDEHYPAYTMGRAADMLGTTQGFLRSLDEAGLITPQRSAGGHRRYSRYQLRLAARVRELVDHGTAIDAACRIVSLEDQLHEAQRLNSELRTQD
>NC_017186|8559516:8633698|8565740_8566811_-|WP_014467685.1|DBSCAN-SWA
MDSSSLKGLLAEHAELETQLADPAVHADQARARKLGRRYAELTPVVRAVHDLDTVRDDLAAAREMASEDAEFAAEAEELAARIPDLESRLTELLLPRDPYDGSDVVMEIKSGEGGEESALFAGDLLRMYLRYAERHGWKAEVLDSVDSDLGGFKDVTLSIKSKAAAVDGVWSRLKFEGGVHRVQRVPATESQGRIHTSASGVLIYPEPEEVEVEIDPNDLRIDVFRSSGPGGQSVNTTDSAVRITHLPTGIVVSCQNEKSQIQNRARALQVLQARLQAVAEEEAAAKASDARRSQVRTVDRSERVRTYNFPENRISDHRVNYKAYNLDQVLDGDLDGVLDALATADREERLAAQSG
>NC_017186|8559516:8633698|8593188_8593929_+|WP_013229561.1|DBSCAN-SWA
MRALITNDDGIGSPGLAALARGAVAHGWTVVVAAPAEEASGTSAGLSAAGDDGRITVEQRQLPGLPDVPAHAVAAHPGLIALAAAQGAFGEPPEVVLSGVNRGANVGRAVLHSGTVGAALTASLNGARALAVSLDVGLEPGPHQHWDTAVTVAATLFDRLAAMPAGTVLNLNVPNRAEVGTPRRAGLAEFGTVRSHVENGDDGAISLTAVVVEGDLPPGSDARLLAEGHPTVTALRSVTEDPNMRL
>NC_017186|8559516:8633698|8578219_8579140_-|WP_013229548.1|DBSCAN-SWA
MGQGHGHGHAIAPASASGRYVRRLAIALGIGAGFMVLEFVVSVTTGSLALLSDAAHMFTDVLGVGMALAAIILARRSGPTVSRTFGLYRAEVLAALANALLLFGVAGYVLIEAVGRIGEPPAVPGLPVLLVAVAGLVANLVSFAVLRSGAKESLNVRGAYLEVLADLIGSVGVLISGAVTLLTGWRYADPIIGVAIGLFVLPRTWTLARRALRILFQHAPQGVDVGAINAELAALPGVADVHDLHVWTLTSGMEVASAHLTLAPPAKQSDVLTEAQNLLSSRYAIEHATLQVEAPQCARRCQELSW
>NC_017186|8559516:8633698|8567305_8569309_-|WP_013229539.1|DBSCAN-SWA
MSNTDLLSDVGSDTAGSNGTAPAPKRAVGGLTGKTVAELRSLAGELGVGETTGMRKGDLIAAIRERQGKSRKPRAAAETLPLDGVGEPPKAAPKAKAEAPAAPAETKPEPKAEAPASAPSDAPPQAERPQQDRQDTPQGQDGQSEEGGRSRRRRGSNRAAGSPDTQQGGDRQQGQGDRQQGGDRQQGQGDRQQGQGGDRQQGDRNRDQQRQGGGNRGDNRNDNRQDGNRQRNNQQDGNRGGQDNRNQQPDDDEEGGRRGRRFRDRRRRGSGGGQREGGSPDTEIRDDDVLLPVAGILDVLDNYAFVRTSGYLAGPNDVYVSLSLVRKYGLRRGDAITGVVRQPRDGEQQRQKFNPLVRVDSINGLEPDEAKRRPDFTKLTPLYPNERLRLETESHKLTTRVIDLIMPVGKGQRALIVSPPKAGKTTIMQDIANAISTNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPADHTSVAELSIERAKRLVEMGHDVVVLLDSITRLGRAYNLAAPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTIFATAMVETGSTMDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLNPDELAVTVKLSRVLHALDSQQAIDLLISRLRKTKTNVEFLMQVSKTALGGGEDD
>NC_017186|8559516:8633698|8580652_8581753_-|WP_013229551.1|DBSCAN-SWA
MAESFQVALDEADVADLRERLRRTRWPEAETVDDWSQGVPLAYVRELCRDWGEEYDFGFARRLNAFPQFRTTVDGVGLHFLHVRSPVAEALPLVLTHGWPGSVLEFLDVIGPLTDPAKHGGDPADAFHVVAPSLPGFGWSDKPALKIGRVAELWDGLMTSLGYDRYGAQGGDWGAAVTNAVARSGHVAGVHVNFAPVRMDTADPTPEERRALADLEEFRRSGSGYSAQQGTRPQTLGYALTDSPAGQAAWIAEKFWAWTDNKGRPEDAVDRQSILDAISVYWFTATAASSARMYWANNDRDLSTVDVPAGVSVFPKEIVRPSRRQAEQRYTDLRWFEQLPVGGHFAALEQPGLFVEQVRGFFRLVR
>NC_017186|8559516:8633698|8622020_8622806_+|WP_013229576.1|DBSCAN-SWA
MLAAAVAVIVVHQTSAPPAGQDPAAPLPDGPVLTVGTDPVDSREFLLQMGTNRAEVFQYFYDHYGVRDTAGFWTTPHGETTPLAMLKQRTTQQLVRLTVQLQLARARNLVEDITYGALVAGMPEENQRRTAAVAQHRPVYGLTSFTEETYFNHVTTNLAVELKQSTEQGMKPPPTAVLHQLYEQLREQNFSCPPPGRQQHGESSAKSQYCADGQQYLPFVAVEPQVVQRWKDDQFESLIAANIRAAHVEINHMVFDKIEAQ
>NC_017186|8559516:8633698|8626794_8627247_-|WP_013229580.1|DBSCAN-SWA
MPEPSNEPAPAPPSWSMDLRGTTAPALVEIRRWASRALARVADAHLGDVLLVATELVTNAYDHGEGPLQVRMSHTPSPCRVRIEVDDNCPDHPQLTVPSLERPGGRGMHIVDKLACSWGVAEHPAGSKTVWAEVSCGGSDAVPCAAVACS
>NC_017186|8559516:8633698|8599060_8600386_+|WP_013229564.1|DBSCAN-SWA
MTAVVAPGALPLIGHLVPLVHNRLEFLRELPAYGDLVRVRVGPWQALVVTSAELTHQVLQDDRTFDKGGYLYDRIRETGGNGLVSCAHRDHRRQRRLVQPSFHRDRLPGYLQVMSKQIDEVLGHWRDGRAVDVHADMQTVTARTMLPSGLPSSVMAQMIEDMNVVLAGVVWRSILPRRLDKVPLPANRRYHRAQERLRRIVTEVIADYRSSDTDHADLLSGLLAFCDPHDGAPGLSDAEIHDQVLTFLLAGTETTANVVSWALHLVARNPDIERRLRAEAAGVAGTTLDDLSRLTLARNVILETVRLFPPVPLLTRITTKDTRLGGHFLPDGTTVVYSPYVVQHQGAHFADPEDFRPDRWDGDGEPLRPPRGALFAFGGGARRCVGDTFGLAEAMVMLSTITHRWSMRSLPGSRVRPAQSLVLGPRTLRMRPQAATPGACS
>NC_017186|8559516:8633698|8574424_8576086_-|WP_013229544.1|tRNA|DBSCAN-SWA
MTPAALADLVRSSAVQVLAARGIDDAVLPEQVTIERPRNPDHGDYATNLALQVAKKAGLKPRDFAEALAAAVSADDGVASAEVAGPGFLNFRLAAAAQGDIVRQVLDAGAAYGRGDALAGTRINLEFVSANPTGPIHLGGTRWAAVGDALGRVLAAQGADVTREYYFNDAGAQIDRFVRSLIAAAKGEPAPEDGYAGGYINDIAAEVIKAEPSALSLPEAERHETFRRIGINLMFSEIKQSLHDFGTDFDVYFHENSLHESGAVDAAVQQLKDSGNLYFDEGAWWLKSSEYGDDKDRVVIKQDGNPAYIAGDLAYFKDKRNRGFDLCIYMLGADHHGYTARLKAAAAAFGDDPATVEVLIGQMVNLVSDGKPVRMSKRAGTVITMEDLVEAVGVDPARYELIRYSVDSTLDVDLDLLRKHSNDNPVYYVQYAHARLCTMLRGAADLGLKSTEDVDLGQLTLPVEGDLIRTIGEFPETVRRAAEMREPHRIARYLEELAGALHKFYAVREARVLPKGDEAATPANHARVALCEAARVVLANGLALVGVSAPERM
>NC_017186|8559516:8633698|8592280_8593201_+|WP_013229560.1|DBSCAN-SWA
MAVFAPSPQLTVTVEETAGVPDVHVHAGGQGVWQSRMIQSLGATPVLCCALGGETGQVLRHLIGVELQIRDVAARNGAYVHDRREGHRDEVVRMPADALSRHELDDLYELTLVAGLGADVTVLSGPAEDDVPVPHSVYERLARDLAGQGARVVVDLSGERLARALAGGPEVVKVSHEELVTDGLAESDTLPDLAKSCREVAKCGARAVVVSRAAEDTLALVEDELWLVESPELTPVDPRGGGDSMTAGLAVGLAQGRSLEEALKLGAAAGAVNVTRHGLGSGSSAAVRELARRVRLKNWEDTGCGH
>NC_017186|8559516:8633698|8618126_8619965_+|WP_013229574.1|DBSCAN-SWA
MRPHHSPRGRHLRRLLAGGTASILMTAAALLPAAPAGAATSASVTVNTAATLGTIPAAGHGLNFAIYDGHMNDAAIPGLVSGARFSALRYPGGSYADGYHWQTHTMEDGGYVAPNTGFDTFMSTVRTAGAQAVVTANYGSGTPAEAAAWVRYANITHGYGVKTWEIGNEVYGNGYYGANWEHDTHADKSPRAYANNVLQFISAMKAVDSTIKIGVVLTTPGGWPDGIVHSGDAMDWNNTVMSIVRDQADFAIVHWYPGAGSARDALSKPRQIASTVAAVRTVIGKYAGANAGRVGIAVTETNPGFQLTSATSALFATDSYLTWWENGAFNLDWWDMHNGSNTPASPADDGTTDYHDEGILSSASTTEPPLNTPLPPYYGLAMTGRAGAPGDTLLATSSSNSLLVSHAVKTSTGVNVVLINQDLGNSATVSLSYNGYTPNGTTTVDQWKKGDTSISTTTQASANSITVAPYSVTVLHTAGGGGSNPAAGVLKGAGSGRCVDVPGAVSTNGTQVALWDCHGGTNQQWTYTSGRQLTVYGTKCLDAAAQGTTAGTKAQIWDCTGAANQQWNLNADGTVTGVQSGLCLDAAANGTANGTPIQLWTCNGGSNQRWSR
>NC_017186|8559516:8633698|8563990_8564422_+|WP_013229535.1|DBSCAN-SWA
MKLISATQLRFGLVGVGNTLVDALGYALLVTLGVPLFVANFISTTTGMLLSFTLNRNFTFRAKDGDVRRQALLFFAVTAFGLWVVQAAIIFAVTAAFPGVNLLLPKFAGIAVGLVWNYVLYNKVVFRQRPAAAEPPVAEVTHD
>NC_017186|8559516:8633698|8582106_8582850_-|WP_013229552.1|integrase|DBSCAN-SWA
MKWTAMPKGKRKVDKRAVPNPIQARTLLAGVGALPRSGPRLEAFFGTMYYAGLRPEEAVSLNKRNLASFPEPVWNGDANEFEYDWGGFRLDKAEPHVGGRWTDSGKTRDDRPLKSRDDDEERTVAFPPDLTRLLWRHVRQFGYGPDGRLFQAEQGGEIPMITYTRAWRAARKAVLTEQVRATPLAGRPYDLRRAAVSTQLAAGVDPATVAAWAGHSVSVLLEIYASFLDGGEQAARRQVETALGSGR
>NC_017186|8559516:8633698|8601667_8603218_-|WP_013229566.1|DBSCAN-SWA
MDMLLSRRRVVTVGAAGLAAPLAGTATAVADPVGTTGTVFDVRKFGAAGDGTTIDSDAVNRAIDAAASTGGTVYFPPGKYASYSIRLRSRVALYFDQNATLLAAKPAGGRGYDPAEPGAGNPYQDFGHSHWHNSLIWGEGVEDVTLHGPGRIDGSGLVASGDQESAPLQGNKAIALKLCRNIAIRDLTIVNGGHFAVLPTGVDNFRIDGLVIDTNRDGINLDCCRNVRIANTTVNSPYDDGIVLKSSYALNQLRATENVTIDNCLVSGYDLGTLVDGTFRTGPYSRVGRIKFGTESNGGFKNIAISNIVFEYCRGLALETVDGGVLEDVTISNLTMRHVQTPIFLRLGARMRGPAGIPVGTLRRVSISDVVAANTDPQYPSTIAGIPGHNVEDIRISNVRQHTAGGLTPADAVANPPELETGYPEPAMFGTLPAYGWFIRHARGLTFDNVEVRYERTDTRPAHMLRDVTDADFHHVRADKATGVPTFTLDAVQDFRVTTSRPVPDTVLDRVDHRDL
>NC_017186|8559516:8633698|8631432_8632413_+|WP_034285067.1|DBSCAN-SWA
MSPPRAADAPVRTALAGLAVLALGVLTALNARSLPVLGDGTTYSAEFTEAAGLSEGNDVRVAGVEVGRVSDVRLRGDHVLVSFRAKGAWLGDATSAAIRLKTVLGQKYLALDPQGEGTLDPGQPIPRSRTTVPYDILAAFGTLSSTVDHIDTARLAKSFDTLSATLANTPQSVRAALTGLSRLSDTLASRDSQLARLLGNTRVVSQTLVDRDAAVRRLLDDGNQLLAEVSNREAAISTLLDGSRQLATELSGLINESRVGPLLTQLDQLTSMLQRNQDALAAGIRAFAPFVRLGTNLAGSGRWIDGYLCGLVLPSFGPVNEEGCHG
>NC_017186|8559516:8633698|8622935_8623109_+|WP_014467698.1|DBSCAN-SWA
MVPEEVLAKSVTALLGPEHATPAQVRATAVEGIQALADGRATALELIAAPARPVSAV
>NC_017186|8559516:8633698|8561604_8562471_-|WP_013229533.1|DBSCAN-SWA
MNRQPLRLAIIEATRILERAGVASPRFDAEVIAAHVLGVERGRLPMVPLVDPPVIEAIGQLVQQRAKRIPLQYLTGWAALGDITVAVGAGVFVPRPETELLLEWGVKFLQGREFPVVVDLCTGSGALALAVAHARPDAVVYAVDIDPQALAWARHNADVHADAGNTPIRLYSGDIGDPTMFAELDGLVDLVLCNPPYVPEGTPVPPEVAEHDPPRAVFAEESGLAVIRHAIAAGARLLRPGGGLAIEHDDTHGSAVPALVRARRVLTGVEGHTDLTGRARFVTARRLG
>NC_017186|8559516:8633698|8594691_8595090_+|WP_013229562.1|DBSCAN-SWA
MAKPLVVLVALIAAFVVAPGAASAASGGDTSATAGWSTFPKPVTDTSKQLSSGEARTDTVNAVFTCNYYSVSPYYVIDFTCNVTQGAIQLWVNCTDGRHLLSGIMRAVGTYNARSICGPPASLVNFGANQLA
>NC_017186|8559516:8633698|8564414_8565683_+|WP_013229536.1|DBSCAN-SWA
MTRTAEPSLTTDQVEPERAETAPAGRRAAWVHGDYARVFAVVLAWNVVLIAVAYLFAPSSPVDEGIPKTGIGSTMSLLAHTYRWDAGNYGEIAVHAYTGSYAPTRAFYPVFPVLVWLVQTVSFGTLGLLAAGFLVNLVATWLAAVALLKIGRHFFDGERAPWLVVAAFLTAPAAFFLHSFYSEAVFCALGFWAYLFALRRQWLWMGLTLIPLTASRITAAVFVGLCFLEFWRSKDWKLRGLLSPNLLWFPAAFLGLGGVLVAMKIQTGDFFASFNALKGVREWSYHQFNPNILGTLWREAKITGHALLGDTPMDAWTLMSHVLPMIGLALLFASSVYVLVALRAKGVPLALFGFASIVMLTMNNNVVSVHRYLLPCLVMYVALVLFGERRPKLRGAVHVVLYANALVCGMIYLRFITGFWSG
>NC_017186|8559516:8633698|8612304_8613513_+|WP_013229571.1|DBSCAN-SWA
MTADDPGSPPSIGPVPRLAATTWTGTADGTRAQIFAEVLTFGPISRIEVARRLGLSQSTVTKAVTPLIDSGYLVEAGSRVDGPGRPQRLIRVAAGRYHAIGVQLGPAGVTGVLTDLRANTLTRLYHPLPEGHEPHTVLAAAAGLIGRLRSAAPRGLLGVGVSLGGHVDPATGRCVHSGILGWDDINVAALLTTATGLPIVVNNDVNAVVIAEQWFGAGRGVRSFAVVAVSAGIGCGLLLNGELHTGATGLAGEFGHLPLNPGGPPCSCGNTGCLEAVAADPAVIAATAAQGGPRCDSTEEVAALARSGNAAALAAYTAMGEALGRGLAALCNLLNLGKIILTGHGMKAFDVFESACLTAFHRHAFSTAATDCELTLEPGGDDLWARGAACLVIREAAGAAHP
>NC_017186|8559516:8633698|8629407_8630067_-|WP_013229583.1|DBSCAN-SWA
MTRVDRAAEGRIQEDGEGAVEARILDAAAHLIAEEGFGRLKIGGVCARSGYARSVVFQHFGDKDGLGQRLVEYAVEEFTDAYSEAVAARTGSANATPMDMLRALLDIIFELIRTMPTLNHAFLALWGDAAAEYSALRGALTEADRRFRFAIAQTVASGVADGSITGVRDPDSYASAMLAQLRGISMQALIDPDGVDLRGLRAELERSVDRLSASFRGTR
>NC_017186|8559516:8633698|8562989_8563994_+|WP_013229534.1|DBSCAN-SWA
MPTEPITRRVAFIFPIYNEEENIDLLHRTVDEVTAPLAGKYDFSFLYVDDGSRDGSLAKLTELSARDQRVTVVELSRNFGHQMAVTAGLDLVDADAVVIMDSDMQDPPRVALELIEKWEEGFDVVYAQRRSRQDSAFKKLTAGGFYWFLRKMAAVDIPKNTGDFRLIDRKVVDELRKYRERDRFLRGLVSYIGFKQTAVLFDRDKRHAGVTGYPLRKMLRFAADGILGFSVTPLRMITRMGYLISFLSFVGILYVGGVKLFAPQTAVPGWAFLGIAMFFLGGIQIIMLGVLGSYIGRTYSQVQNRPLYGVASVRTGPGTPVEAREGADAGRGAR
>NC_017186|8559516:8633698|8595335_8598395_+|WP_013229563.1|DBSCAN-SWA
MHVQVLGPVRVWQDGEELDLGPPGRRALLGVLALARGRALRRTALVDALWGDTPPPSATNIIQTHVKHLRRVLDPERHAYARSQRIPTVGDGYALRISPDQSDVDRFYRQVQAAEQERQAGRSDQTAAMLGEALGLWHGQPLADLPALVGHPTVLTLFEARRDAVLAYAEALLTTGRASEALPVVIEETATHPLDEALAAMLVRMYTASGQRDKGFAVYDLTRKLLAAELGVAPGPDLAEAHAMLVRETASTAPFASKRHLPAELPAKVSEVVDRARQQDERLAGQVVPARHRSGRRTNALARYEQLKQHLGIDPGPPLWQAHHHVLTAEPAVATPVGTERAPVPRQLPAPPRPFTGRVAELAELTAAMRAQAEPGGTVVISAIGGTGGIGKTWLALHWAHQHIDRFPDGQLFVNLRGFDPTGDPLTTQTAVRGFLAALSVEPSAIPAELDAQVGLYRSLLAGKRMLVVLDNARDTAQLAPLLPGSPSCAVLVTSRSRLSGLVTAHDAHPLTMDVLSESAARQLLQARLGAQRPAAEPGAMAELIACCGGFPLALSIVASQARAHPQFPLAALAAELRDASTRLGALDDTDQAVGVPAVLSWSYRALTPEGARTFGLIGLAPGPDIDLPATACLTGLPIDAARRVLRALDQVSLVHQHVPGRWRMHDLVRLYAADQARQDQPHADREAALRRVVAFYLHTADAADQLLDPHRQPIRLDPPPPGCLPYPLSDASAALAWFDTEHACLLAAHRAAISNGWHQTVWQLTCTLFTFHHRRGHRHDLLAVCRTGAVAAEHLPDPDIHVRAHQRLGRAYADLWRLEEAIDHLRRSLAIACQYHDHTNQAHAHHALARVWEQQGDNRLALEQATHALNLFRSLDDPVWHAATLNMVGWLSAQLGEYEQARRHCQAALTLQRHHQDPDGEAITLDSLGYIDHHTGRHRQAICHYQQALTLRRAIGHTYEVAKNLDAMGRPYTALGQPDQARAVLREALEWYRQLGRGEDAARVQQQLDDHFRDLTPS
>NC_017186|8559516:8633698|8588511_8589342_+|WP_158314388.1|transposase|DBSCAN-SWA
MARLLNVSRSGYYAHATRAAATVLAPRRQRRADLEVKITQAHQDSGGTYGSPRITAELRDQGEVVTAKTVAKIMAGVGLEGISPRTFKVRTTVVDPAASFPPDLVGRHFDRGRTDAVWLTDITYLTCGEGDMFLCAIRDGHSRKVLGYSVSDHISAEMVTAAIDDAVAGRGSGCRGTILHSDRGGEFTANVTAQACFGHGLRRSMGETGICWDNSPAESFWSTFKHEEYYRHVYATKTELVAAIDKWLNFYNSRRRHSSIGMLSPNDYEKSLPVVA
>NC_017186|8559516:8633698|8571658_8572984_-|WP_013229542.1|DBSCAN-SWA
MSASELPAADRRPIRVALLGCGTVGGEVARLLTEQAGELAARAGAPVELAGIAVRRPDKHPELPPELLTADAEKLVTSDDVDVVVELVGGIEPVRGWLLAALKAGKSVVTANKALLAEHSADLFEAADAAGADLYFEAAVAGAIPLLRPLRESLAGDRITRVMGIVNGTTNYILSAMDSTGAGYAETLDEASRLGYAEADPTADVDGYDAASKAAILASLAFHTRVTASDVHREGIADVTASDLAAARGLGRTVKLLAICERVTDDDGVESVSARVHPVMIPRRHQLAGVGGAFNAVYVEADAAGELMFYGQGAGGAPTASAVLGDLVAVARNRVVGGRGPRESAHAALPVRPMGQTPTRYHVSLSVADRAGVLAQVAQAFADHGVSIAAVRQSDVGDRASLVVVTHQAPDAALQSTVDEIGRLDVVHEVVSVMRVEGEDQ
>NC_017186|8559516:8633698|8588101_8588425_+|WP_013223344.1|transposase|DBSCAN-SWA
MPPRKRRSYPAEYKVEAAHRVIDSGRTIAEVARELGLDAGMLSVWVKDERRRVTAAEVHGENPLEAAERAELLRLRGQVAELEKDNAFLVKASAYFAAMQKNRPGSL
>NC_017186|8559516:8633698|8610004_8612206_+|WP_013229570.1|DBSCAN-SWA
MRARRPWPLATMAVLAVSTVVTVAPADAATAAPGPDLAVDVLADRQPISEDIYGMNFASEELAAELRLPVQRWGGNSTTRYNFRFDNTNRASDWYFENIDEATPDPAALPDGSVTDLTHERNVRTGSKSLFTVPLIGWVPKARGKACGFSVAKYGPQQSTDSWAPDCGNGVRPDGTNVTGNDPHDTSVEAGAQYVEDWIHHLTGKYGTAAGGGVRYYDLDNEPDLWQHTHRDVHPQGAGAVELRDRTYDIGAAVKAADPSAKTMGPVGWGYMSLLHSGLGDADRPNHGGVDFGEWYLAQMRAYEQQHGVRILDYYDNHIYPQQSGVSSSDAGDAGTQALRLRSTRQLWDPTYVDESWINDKIRFIPRMKDMVARNYPGTKTAITEYSWGAFDSVNGALAQADVLGIFGREGLDLATLWTAPSAGQPVADAFRMYRDYDGRGGRFGDTRIRATSTDQDKVSIYGAERATDGATTLMVVNKTGGDLTSPVAMSGRGAGTAQVYRYSGADPTGIVHEADQAVSATGFTATLPAGSITLYVIPKDDTPTLPAPGAPTASDLTATGVTLSWPAVTGAADYTVERDGSPAGRTATTTLAVTGLKPDTAYTFTVRANNAAGTSSPPSPALTVRTKPDQSGTGCTAAVTVTGKWPGQFQLDLTVRNRGTTSGTGWTASLGLAGGMSVAQTWNGVTTTTGTTATVRNASWNGALAPGAFATAGMILNGDPAGWTPTPTCSLT
>NC_017186|8559516:8633698|8630182_8631412_+|WP_013229584.1|DBSCAN-SWA
MTAKTVLVSGAGIAGPSAAHWLHRGGYQVTVVESAPGLRPGGQAVDFRGEQVKLLAAMGVLDEIRRYETAMGDQTVLGLDGRPVLTVPGAAWSGEVEILRGDLARILYENTADHTEYVFGDRVTSLTETADGVEVTFRHGAPRTFDLVVGADGVHSGVRAAAFGPEPDFRTDLGFGIAGYTVPNHLGLDHTSIMYNEPGRGLMVGSHRLPDRLHVGLVFAADGVEFHRRTAVEQSRLITQLFADTGWETPKLLEALPAADDLYVDSISQIHLDRWSKGRVVLLGDAAWCAGPGGSGTGLAMMGAQVLAGELAAAGGDHVTAFAKYEQRLRKPATVGQKNGKGAGNFLAPRTAAKIRSRNRAYRMLSTRLLGGIFLKMTDRAANALEYREYPALTAAWFRSSGDPAGGRA
>NC_017186|8559516:8633698|8627827_8628997_+|WP_071831505.1|DBSCAN-SWA
MGSHGSIPRKKALAVSAALVTIAALAPPSAAAAATTLYVAPNGKDSAAGTQADPTTLPAALTRIGSGGTISLRGGTYSYAQTVTIAPGNSGTSSARKTLSAYPGETPVLNFSAMKEDPANRGLAVNGSYWRVAGIVVERAGDNGIFVGGSNNVLERVVTRFNHDSGLQISRMASSTPKDQWPSNNLVVSSESHDNADSDGEDADGFAAKLTAGPGNVFRYDVSHNNIDDGWDLYTKTDTGPIGPVTIEDSLSYANGTLSNGTVNKNGDRNGFKLGGDKIAVNHIVRRDIAYRNGHHGFTYNSNPGSMSVSDNVGIDNAERNFSFDTGTSVFRNDTSCRFLSGGSNDKTVGSVDSSDQFWTGKNGSRCSSYAGTMKWSFASDGRLVVTFG
>NC_017186|8559516:8633698|8577097_8577811_+|WP_013229546.1|DBSCAN-SWA
MTTEAGLDTDEVTEQPTWSRWVIIGGTLLAVLLIGATAGMFFTRAVDDPATATPAAGSVEVGFAQDMSTHHLQAVTMAGIARDRTTDPEIKQLSFDIERTQLEQVGRMKGWLMLWDQPEQPIGAPMQWMTETMTGHDGMSMAPSSVNPAEGPLMPGMATDTDLKKLRSLSGREFDVYFLQLMLRHHQGGTSMAQYAAAHSTLPALKALVNSILTSQGAEMDQIKLMLSGRGAQPLPA
>NC_017186|8559516:8633698|8603332_8605417_-|WP_013229567.1|DBSCAN-SWA
MKAFTSNRRRWSPVRLTAAVVAAVAGVGAVAVPAAAVTGSTIVGVASGRCLDVVGQSQADKAGVDIYDCNGQANQAWTFTAAGELRVYDSPKCLDVAGQATTAPAVVQIYTCNGGANQKWRIDSTGTIVGVQSGLCLDVTGAGTANSTAVGLWTCNGQANQQWRTASGGDTQPPTVPGNPRVSNLACDTVTFAWNASTDNVGVAFYDVYHDGQLIKSVSGATLSTDLTVVPGTTWGLYVNARDAAGNVSQASTTVPITPPQCQADTQPPTAPAALSGTAAGTTVTLRWTAASDNIGVRAYDIYRDNAKIGTVTGTASTPPATTFTDSALAANTTYQYYVVARDAQANVSAHSNTATVTTGGACGASVCAVTQIATDTDIPWGLATLPDGTILYTRRDAQDIVHLNPATGAKTTVGTVPNVQSTDGEGGLTGLAVSSTYGSDHWLYIMHTSPSDNRIVRIKLENDKLTTSSEQILLSGILRNKFHDGGRLRFGPDGKLYAGTGDAQNGDNAQNTTSLNGKVLRLNPDGTVPSDNPFGNYVWSYGHRNPQGLAFDSQGRLWEQEFGNSVMDETNLITKGGNYGWPACEGTSGSCGTAGFITPKHTYPVAEGSCSGIAVVRDVLYVACERGTRMYREVISGSELTNVQTYFNGTYGRLRTVEPAPDGGLWLTTTNNGDKDSIPNNSNEKIFHVTLGT
>NC_017186|8559516:8633698|8619922_8621911_+|WP_013229575.1|DBSCAN-SWA
MDLQRRQQPAVVPVRRGITRAFGVAVGLVLGLAVPPVTTAAAGVTTWWWVDCASAGNGNGTAQSSPWNTLSSVNAHTFKAGDGLVFATGTSCRGQLALRGSGASGNPIVIGQWRSGHGSGKPILAGGGVTPATVYLHDNEYVTVEDLEVTNSGASAGDRAGILAYNDTGSTLHGITITANTVDNVNGYRWGYYGVNAGIAVDIDGGLANPGVYSGVTISDNAVWNVNRAGVWVGSLAENGAISARSTGVTISGNQMTDLGADGIVTRYTSGAQILNNVVYDAGSWSGGANSGSPSYYNPYPDGIWPVNSDNPVVQGNEVFGFVSQGAGDGDALDCDLHTTNCLMQDNYSHDNVDGLWMDCSGAGGRGEVFRYNISQNDATARNGIFNNGCGGSPTPAVYNNTVYIGSGSPKIDSANRANWGSGTAFTDNIIDNQGNGGFGTSARWDHTLFHGSGNRPADNTNAVVGDPRFAHPNGAGNGRGTAAAAYALSSGSAAIGTAVAIAGAPGRDFSGNSVCASPDIGAMQNLCGPAGQVNNPGFETGSLSPWTNLAGAGVVGDNAHTGSYAVRTGNVNSGVSQTVYGLASNRTYTLTGWVKSSNGSDAVYVGVKNYGGTETSIPATSSTYTRISVTFTTGSGSTSATIYCWKNGGSAASYCDDFSVS
>NC_017186|8559516:8633698|8629135_8629411_+|WP_013229582.1|DBSCAN-SWA
MGALGTLLGFALSLYLLVLIARMVLDWVAVVASTPPWARRARGLAYAATEPVIGPVRRVVRPVRIGGLSLDLAFTLVFVGVIVLRSIVYVL
>NC_017186|8559516:8633698|8570600_8571662_-|WP_013229541.1|DBSCAN-SWA
MIRHPWPGLIEAYRDRVPVPDGARVVTLGEGNTPLLPAHHLSELTGCEVYLKVEGANPTGSFKDRGMTVAITHALASGLKAVICASTGNTSASAAAYAARAGLTCAVLVPQGKIAMGKLAQAVLHGARILQVDGNFDDCLELARKTAADYPVTLVNSVNPVRIAGQKTAAFEICDVLGTAPDIHCLPVGNAGNITAYWAGYSEYAADDVVKNTPRMFGFQAAGAAPLVHGEPVRDPDTIATAIRIGSPASWTAAVKAKDESEGLFEAVTDEKILEAYRLLAGREGVFVEPASATSVAGLLATAADGRLPRGSRVVCTVTGHGLKDPQTALAGNVEVEPLAVDPSAVAAALDLR
>NC_017186|8559516:8633698|8623321_8625199_+|WP_013229577.1|DBSCAN-SWA
MLAALLTAQVIAAPPASAAGLSLSVGVSAARHPISPGIYGLNGGDPAFNAEIGQTVARWGGNASSRYNFKNHTYNTGSDWYFENIVADQEHSVEGMVGSNLGRGIKPVVTVPLSGWVAKDSPSSHPFACGFPATRFPQQDSFDQWDPHCGNGKLNQENLTGVPTDTSVPADAAFDGEMVSHLVDQFGTAAQGGVPIYELDNEPVLWSSTHRDVHPDPVSDDELGGKGTAAAAAIKAADPSAAVLGPSGWGYCEWVASGVDGCGPGADSAAHGGLNLSQWYLKNMKDYSDAHGGKRFLDYFDQHFYPQISGDKTPEANALRLRSIRSLWDPTYVEESWIGPSGVNAPPLQFIRTMKSWVDRYYPGTKTAITEYNWGALDDINGALAEADILGVFGREGLDLATMWGEPKPTDPGAYAFRMYRNYDGAGSRFGDVSVSATAADQGQLAVYAAQRSSDQALTVMVVNKTGGDLTSPLSVAGFDNAAAAQRFTYSPANLGAIVRGDDLPASNGHVDATYPANSITLLVLPAAGCSASLSVNGDWGTGHVATVTVTNDRRTAITGWRVSWTWPGDQRITNSWNTTLKQNAASVVASDAGWNGPIGAGGSTTFGFQATGTAPPPKLTCTPA
>NC_017186|8559516:8633698|8582984_8583956_+|WP_176742245.1|DBSCAN-SWA
MKAAVHTRYGPPEVVRIREVDRPAIGDRDVLVRVHATTVNRTDCAYRAARPLFMRLLTGIARPRRTIMGTEFAGQVEAVGRGVMSFSVGDQVFGYNEGAFGAHAEYLSVPEDGSIATMPAGVTFEQAAPGTEGAHYALACIRHAGTRAGQDVLVYGATGGIGSAAVQLLKSLDVTVTAVCATESLALVKRLGADRVVDYTVGDFTEDEQTYDAVFDAVGKSTFGHCRRLLKPGGVYLSSELGPWAQNLMLALVTPLLRGRKVKFPFPRDNQAIVRHLRELIESGDFTPVIDRRYALDQIVDAYRYVEAGQKIGNVVITVTDVD
>NC_017186|8559516:8633698|8577814_8578153_-|WP_013229547.1|DBSCAN-SWA
MAIEAVELVMTALAAGAAAAAKETATDAVKKAYDGLKSGVRRLIGRLPDDPEELAAELAAANVGDDAAVLEAARAVLREADPEGARAGKYHVTVTDSKGVQIGDGNTMNLEF
>NC_017186|8559516:8633698|8600382_8601540_+|WP_013229565.1|DBSCAN-SWA
MTRAEPRDNWFYPRDIEDDLKGTDLPEEIVAETLACAWEYTRCVIPQFIDWDRYIAFTRIIVIGIIAEFRGGLVDVAAGDNLLGYDLDELLDTVFAGTPGHEEMAREYRTFLLITADKSSERCNSELFRRYVNALTRSPKDWFRLRDSDALARFTIAAAMACNDITDTWFSEEEFQILTELGDTLYDAVAYYKHRAEGETNSTFAYVGHELRAESYRRCREALWALDVAWARAPAHRATINFLRYFGGPIHMMMRRYRFTEEDLTIGRPETEHVVAQTRQNIKLWHRVDVTEKSTHSVRYANVVARSEELMFPGLADMLESAADAHCDHCRHRLSYGAEPLGRFGGVELCDSCRADWATYLRTFPARAAEVFPLVGVEQAIVGLA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
8555328:8555345	attL	NA	NA	NA	NA
WP_013229532.1|8559516_8561490_+|protease	M6 family metalloprotease domain-containing protein	NA	NA	NA	NA
WP_013229533.1|8561604_8562471_-	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_013229534.1|8562989_8563994_+	glycosyltransferase family 2 protein	A8CG95	Salmonella_phage	6.5e-50	36.8
WP_013229535.1|8563990_8564422_+	GtrA family protein	NA	NA	NA	NA
WP_013229536.1|8564414_8565683_+	hypothetical protein	NA	NA	NA	NA
WP_014467685.1|8565740_8566811_-	peptide chain release factor 1	W8EDB3	Pseudomonas_phage	3.1e-05	37.5
WP_013229538.1|8566892_8567123_-	50S ribosomal protein L31	NA	NA	NA	NA
WP_013229539.1|8567305_8569309_-	transcription termination factor Rho	NA	NA	NA	NA
WP_013229540.1|8569719_8570604_-	homoserine kinase	NA	NA	NA	NA
WP_013229541.1|8570600_8571662_-	threonine synthase	NA	NA	NA	NA
WP_013229542.1|8571658_8572984_-	homoserine dehydrogenase	NA	NA	NA	NA
WP_013229543.1|8572990_8574421_-	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_013229544.1|8574424_8576086_-|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_013229545.1|8576282_8577101_+	DUF3105 domain-containing protein	NA	NA	NA	NA
WP_013229546.1|8577097_8577811_+	DUF305 domain-containing protein	NA	NA	NA	NA
WP_013229547.1|8577814_8578153_-	hypothetical protein	NA	NA	NA	NA
WP_013229548.1|8578219_8579140_-	cation transporter	NA	NA	NA	NA
WP_013229549.1|8579293_8579713_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_013229550.1|8579819_8580656_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_013229551.1|8580652_8581753_-	epoxide hydrolase	NA	NA	NA	NA
WP_013229552.1|8582106_8582850_-|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_176742245.1|8582984_8583956_+	zinc-binding dehydrogenase	NA	NA	NA	NA
WP_141748543.1|8584127_8584532_-|transposase	IS66 family transposase zinc-finger binding domain-containing protein	NA	NA	NA	NA
WP_071831756.1|8585060_8585630_-	TIGR03086 family protein	NA	NA	NA	NA
WP_013229555.1|8585784_8586438_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_013229556.1|8587038_8587404_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_013223344.1|8588101_8588425_+|transposase	IS3 family transposase	NA	NA	NA	NA
WP_158314388.1|8588511_8589342_+|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-30	33.0
WP_013229557.1|8589795_8590089_+	hypothetical protein	NA	NA	NA	NA
WP_013229558.1|8590133_8591753_-	DUF839 domain-containing protein	NA	NA	NA	NA
8590943:8590960	attR	NA	NA	NA	NA
WP_013229559.1|8591855_8592236_+	hypothetical protein	NA	NA	NA	NA
WP_013229560.1|8592280_8593201_+	1-phosphofructokinase	NA	NA	NA	NA
WP_013229561.1|8593188_8593929_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.3e-15	35.0
WP_013229562.1|8594691_8595090_+	hypothetical protein	NA	NA	NA	NA
WP_013229563.1|8595335_8598395_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_013229564.1|8599060_8600386_+	cytochrome P450	V5UQK0	Mycobacterium_phage	1.6e-27	25.1
WP_013229565.1|8600382_8601540_+	hypothetical protein	NA	NA	NA	NA
WP_013229566.1|8601667_8603218_-	glycoside hydrolase family 28 protein	NA	NA	NA	NA
WP_013229567.1|8603332_8605417_-	PQQ-dependent sugar dehydrogenase	NA	NA	NA	NA
WP_013229568.1|8605620_8607201_-	ricin-type beta-trefoil lectin domain protein	A0A2P0VP48	Tetraselmis_virus	1.9e-48	30.2
WP_013229569.1|8608435_8609887_+	ricin-type beta-trefoil lectin domain protein	NA	NA	NA	NA
WP_013229570.1|8610004_8612206_+	cellulose binding domain-containing protein	NA	NA	NA	NA
WP_013229571.1|8612304_8613513_+	ROK family transcriptional regulator	NA	NA	NA	NA
WP_013229572.1|8614118_8616536_+	DUF4982 domain-containing protein	NA	NA	NA	NA
WP_013229573.1|8616561_8618031_+	ricin-type beta-trefoil lectin domain protein	NA	NA	NA	NA
WP_013229574.1|8618126_8619965_+	ricin-type beta-trefoil lectin domain protein	NA	NA	NA	NA
WP_013229575.1|8619922_8621911_+	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_013229576.1|8622020_8622806_+	hypothetical protein	NA	NA	NA	NA
WP_014467698.1|8622935_8623109_+	hypothetical protein	NA	NA	NA	NA
WP_013229577.1|8623321_8625199_+	cellulose binding domain-containing protein	NA	NA	NA	NA
WP_013229578.1|8625365_8625698_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_013229579.1|8626434_8626695_+	hypothetical protein	NA	NA	NA	NA
WP_013229580.1|8626794_8627247_-	ATP-binding protein	A0A1V0E640	Streptomyces_phage	1.2e-11	41.7
WP_071831505.1|8627827_8628997_+	pectate lyase	NA	NA	NA	NA
WP_013229582.1|8629135_8629411_+	YggT family protein	NA	NA	NA	NA
WP_013229583.1|8629407_8630067_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_013229584.1|8630182_8631412_+	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_034285067.1|8631432_8632413_+	MCE family protein	NA	NA	NA	NA
WP_080582981.1|8632588_8633698_-|transposase	ISAs1 family transposase	NA	NA	NA	NA