CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017242	Brachyspira intermedia PWS/A plasmid pInt, complete sequence	0 crisprs	NA	0	0	0	0
NC_017243	Brachyspira intermedia PWS/A, complete sequence	12 crisprs	DinG,csa3	2	1	2	0

1. NC_017243

CRISPR-Cas detection and classification

Crispr_ID: NC_017243_1

• CRISPR_ID: NC_017243_1
• CRISPR_location: 199015-199123
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_1

Consensus_repeat	Method
CTGATAGAGTTTTTAAAGCGAGATTTTTTATATATAA	CRISPRCasFinder

spacers of NC_017243_1

>1.1|199052|35|NC_017243|CRISPRCasFinder
GCAAAAATAAAAAATCGAGCGTCTATCAGCTTTAG

CRISPR arrays and Neighbor proteins around NC_017243_1

CRISPR arrays

The CRISPR arrays of NC_017243_1

>merge|NC_017243|1|199015-199123|CRISPRCasFinder
CTGATAGAGTTTTTAAAGCGAGATTTTTTATATATAAGCAAAAATAAAAAATCGAGCGTCTATCAGCTTTAGCTGATAGAGTTTTTAAAGCGATATTTTTTATATATAA

>NC_017243|1|1|199015-199123|CRISPRCasFinder
CTGATAGAGTTTTTAAAGCGAGATTTTTTATATATAA	GCAAAAATAAAAAATCGAGCGTCTATCAGCTTTAG
CTGATAGAGTTTTTAAAGCGATATTTTTTATATATAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_041177136.1|207320_207782_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177135.1|203460_204801_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177134.1|202902_203382_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486676.1|195473_196085_-|dTMP-kinase	unknown	unknown	gnl|CDD|234814
NC_017243.1|WP_014486677.1|196445_197597_-|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl|CDD|234638
NC_017243.1|WP_014486672.1|191050_192853_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|223910
NC_017243.1|WP_014486671.1|189085_190258_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177132.1|199357_200629_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_049783517.1|201382_202681_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177131.1|193960_195004_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486680.1|200754_201282_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486678.1|197815_198613_-|flavin-reductase	unknown	unknown	gnl|CDD|224766
NC_017243.1|WP_014486673.1|192900_193797_-|AAA-domain-containing-protein	unknown	unknown	gnl|CDD|336785
NC_017243.1|WP_014486685.1|205836_207147_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486687.1|208161_208686_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177137.1|208778_210113_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486670.1|188632_188938_+|hypothetical-protein	unknown	unknown	gnl|CDD|379725
NC_017243.1|WP_014486668.1|187057_187831_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_017243.1|WP_041177138.1|210211_212065_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl|CDD|235362
NC_017243.1|WP_014486675.1|195088_195505_+|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|239942

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014486678.1|197815_198613_-|flavin-reductase	gnl|CDD|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	1.77749e-34
NC_017243.1|WP_014486676.1|195473_196085_-|dTMP-kinase	gnl|CDD|234814	PRK00698, tmk, thymidylate kinase; Validated.	1.0443e-52
NC_017243.1|WP_014486673.1|192900_193797_-|AAA-domain-containing-protein	gnl|CDD|336785	pfam07728, AAA_5, AAA domain (dynein-related subfamily). This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.	2.35349e-17
NC_017243.1|WP_041177138.1|210211_212065_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl|CDD|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_017243.1|WP_014486670.1|188632_188938_+|hypothetical-protein	gnl|CDD|379725	pfam15428, Imm26, Immunity protein 26. A predicted immunity protein with mostly all-beta fold and several conserved hydrophobic residues. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, usually containing a domain of the Tox-URI1 or Tox-HNH family. The protein is also found heterogeneous poly-immunity loci.	0.00455939
NC_017243.1|WP_014486668.1|187057_187831_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	9.39305e-25
NC_017243.1|WP_014486672.1|191050_192853_+|methyl-accepting-chemotaxis-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	5.4652e-56
NC_017243.1|WP_014486677.1|196445_197597_-|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl|CDD|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	1.46728e-158
NC_017243.1|WP_014486675.1|195088_195505_+|single-stranded-DNA-binding-protein	gnl|CDD|239942	cd04496, SSB_OBF, SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.	2.58351e-24

Protein sequences

>NC_017243.1|WP_014486678.1|197815_198613_-|flavin-reductase
MNDFALTKLSYGMYILTTMDNDKPVGCTINTSTQITATPTTIMISVNRNNYTNECIKKHGKFALSILSEKSDSTLIGGFGFRSSRDNNKFENVAYEMKEGLPVIKAANAYLVCKVVNSFEVYTHTIFIGELLDADIFDNQTASMTYAYYHNVVKGTTPPNASTANAYKKEDSNSNKAVYKCKTCGFEYKGDTPFEDLPEDWVCPICGEPKKNFVKVEPNKNKSSAVYKCRTCNHIYNGDIPFEDLPSDWKCPICGEPKSNFEKIS
>NC_017243.1|WP_014486677.1|196445_197597_-|phospho-N-acetylmuramoyl-pentapeptide--transferase
MLYQIFYPLRESFFGFNLFRYITFRTAGAVATALILVLLFAPNIIEKLRKLNFGQVVRDDGPETHLVKTGTPTMGGIFIVGSILISVLLWAELDNLKIILLTVSLVILSIAGFLDDFLKIKYKNSKGLPGKYKIFFQTFVGIIIGVYLYYFDKSTFLMTFELNQGIGVLEAVKVAQVPSSTIFLPFASTIYIDLKILYIPFATFVVVSMSNAVNLTDGLDGLAIGLLIIMSMALAVLSYVSGNSLIATYLKIPFISDAGEVTVFVGALIGAGLGFLWFNAHPAQVFMGDVGSLSLGGVLGIIALFIKHELLLVIIGAVYVAEALSVVLQVFSYKFFNKKRIFKMAPLHHHFEKSGWKETQVVFRFYIIGIIMALIGIATLKIR
>NC_017243.1|WP_014486676.1|195473_196085_-|dTMP-kinase
MKGKLIVLEGIDGSGKSSIGMMLTDALNSLGIKSIYTFEPTHAYYGSKLRESMLSKDLKPEEELSLFIADRKEHIKHMIKPAINDGYVIVLDRYMYSSIAYQGAKGIDKEYIYNLHKDFILEPDLVFILHLNIETALNRIMEKRGFVDRFENKHYLEEVDKVFYSFNASYIHHIDASKTQESIKDEILNTIKESKILPLDSLQ
>NC_017243.1|WP_014486675.1|195088_195505_+|single-stranded-DNA-binding-protein
MSGNANIIVIEGRLTKDPTYMKTKNGKSLCKFSIANNRFYYTNGTLQKEVYFFDLVTWGYNADRAAVTLFKGRHVLVSGELRQNIYTAKDGTKKSAIYILALDIKNLDKKSIGNTSYTKTANNQIVSDFIEENLEEVF
>NC_017243.1|WP_041177131.1|193960_195004_+|hypothetical-protein
MFKKSLYVFILIMLFISCKNNNQNSSSEKNKNGSEIQESKFYLLEGSISGEKADMYLYVNEKDKKVSGYYYTKNKKSVITGTINNKKLNLQEVDENNNMHASIVGNLSDDIVLSAEIKYEESEEVKDMEFSLNRNLPVYYADIIDYYKNESISNSIFSYHRTLFLFSKSNDMNSVDMESSINYVEEECDNYYNEWKGLLDVSNTTYEIDNTINVGYIDNKIIALDNYSSMYTGGDYTAKANIQEVFSLESSNLITIRDLISDFNNPDLISLMRDKILETGYSKEDYYEFNSITLESSSFRILPNSINFVWQANDISPYSVGITEISFTFEELKPYVKDVSPLYYLFL
>NC_017243.1|WP_014486673.1|192900_193797_-|AAA-domain-containing-protein
MEKVQIENVELTLSHPDNLNIKWTGQNDLVRQIMASWHLISEDDIPLNPRIVGKPGAGKTTLSYYVGKELLNRDVYIFQCTVDTRPEDLIIIPVISENNKISYHASSLVTAMIKGGVAILDEGNRMSEKTWASLAPLLDDRRYVESVIAGIKIKAHPDFRVIVTMNDDASTFELPEYIHSRLQPTIELPFPDVKEEYDILKMNLPFADDEILKITVGFLQKSHINNASFSVRDGINMARYAMKLYKSNIASSRDTAFLIALKSVLGTEGLRILSLNMDDRDNKDRRRNMDDDDGTNIL
>NC_017243.1|WP_014486672.1|191050_192853_+|methyl-accepting-chemotaxis-protein
MKRGLMFKFLSIFSIFLFAAFLAILFIYKPIYKAKFLKEKYFQTLNSKNETEAYVKEIKNTVNLIVNNLEANPDLETFGNFITNVQKTGSGYLNMYFGDTVPYSEGGVYINTLEEYPRTYNQISRPWYKDAIATNDIAISDPYIDFAVNELTVTFSKAIYTNGKLKGVFAIDFADMNSIMKDIKENFDESFYIVSPNGIYMTHENSDYVLEENKNLFTDPLFTSFKGNLISHVGEVKVVGNQWYAVQKTDNAPWILIFKGDASELNNQFMILMLVIFVVMVILLFLEGFLVYKIVKPLKNTIKIIDLMKEGNFNSVFNKEDLALKDESGHLVNSVNDMQNKISSIVSEIKMNMASINNSSGQISNGIDNLSDRTSSQAAAIEQVSGAIENLFSSISETSKHTNDVKEMSNKVADSTKLGVEAVTQISNNMVDISESSKEISDIIKLIQSIAFQTNILALNAAVEAARAGDQGKGFAVVATEIRSLAQNVNDAAGKITTIIENTVAKIETGDESVKHSLEILLNIESSANEVSEVLTNLYNAVSEEEGSVKEIALAMNELNNITQENADLVHNSAILGREVSNNTESVYSELEYFKLHKIG
>NC_017243.1|WP_014486671.1|189085_190258_-|hypothetical-protein
MNCYKISQLYFKRGKTMLEYKCDKCETELGYKGLCFKCKAEEERNKTLALTDDEIKEIINKYIKDLKEKNVDKELSNGIYIYDLIAYRNIDLKDIAKKALEKKIYYPEVFYYKASEEIRDELIKRIRATKDYSEGANLLSCLAMQGDDVALDCLYDFEMNPREWRKKLYVDSSVYAECAGWTFDKDKKRQILNFDKCYYLDKAQIKEEKEKSPIKIASLRDENCPECGCRNMDMAIIDGRDERLKFIGVDGIIKASCCPNCVIYNTTYSKYDLKGGSEILPFDKESENYYASEENYIEEEELNSMHNNNYILSKNEVPLFYGAFDDTLNTIGGFANWVQDWEYMKCPSCGKKMKYLMQIHWHTIESMAEGTLFIEICTDCNITAMLHQQT
>NC_017243.1|WP_014486670.1|188632_188938_+|hypothetical-protein
MFLPNDIKDNIKNYSKTNFTSEENYAFGRLIEIDKSGGDLIEIFNYTGNIPNDKDDIIKSGLMFDPLHISMAFTKKRWRFIFEELNYDRERDSNYSKIIFY
>NC_017243.1|WP_014486668.1|187057_187831_+|tetratricopeptide-repeat-protein
MSSEKYYEEGLNYFKERKYKEAIESFDKAIELDPNNSNTYYNRGITKVNLGQYEEAIKDYDKAIELNPNDSDTYNNRGIAKYNLGQYQEAIKDYDKAIELDSNDSDSYNNRGIAKKNLGQYKEAIKDYDKAIELDHNYSSAYSNRGIAKKNLGLYEEAIKDYDKAIELDTNDSNAYNNRGLAKGSLGQYKEAIKDFDKSIELNPSYSDVYNNRGVSKENLGQYKDALKDYKKALELDSNNNIAKNNIKNLQNKYGLK
>NC_017243.1|WP_041177132.1|199357_200629_-|hypothetical-protein
MKKSYIFLFIIFMFIASCGNKVTAPSVSDITYYEPNNAIRKTYYYKINDGKTDAMIAVEGTFKKLAESANAIIYVEESQIDKGITKGDILSFLREFENYIPKEIEIYGEIPDFDGNGKVIFLMANLNTNITTSITGGYFSANDLIYGKSGVPGEYLHINVPTSESTIGLMMHELQHLINYYNNAMLKNKAMDIWLNESLSESTSHLFSSTLTDSRINFFINNPYYSFYSWYFMYTDWSFVFTPGHVLLSYASSSMFMKWLDARTGGNFNIYKEIAHSDPSLTSEQRLLNITSKYGLGNDMDTVLLNWIEGVSKNEVQGLNIAPIDPTDKNFNQNGSIPLLPKSLVVYSTANNNISGNKLLTRQLGQTGLSVVINNSVNTTAGLANKEDVVNLTIKKADNLNSSIKYQRANLTDELFYIDKVID
>NC_017243.1|WP_014486680.1|200754_201282_+|hypothetical-protein
MNKFRIDVIVFFIIKLLEVKMNKKVKYIIFIISVLIFISGCKNNATNPSTFEEIGKYRGTWVADKCEAIDFNTDKWIEKEYPISIEINNDTDVLIMNVPVDSVKYLKDTIDTFDLYVSVDKAPLLPPPEITGTVSEVYYRMAFNSYNSATMVMIIKTTDNINSSIFSLIRCSLKK
>NC_017243.1|WP_049783517.1|201382_202681_-|hypothetical-protein
MFIISCGNKVTAPSVSDITYYDPNNTIIKTYTYSIKDNKDQSMIAKEGAFKKIAESANAIIYVEESQIDKGITKAGVISFLRKFENYLPREIEIYGEIPDIDGNGKVIFLMADINTNVTTTGLGGYFQPSDLINGKNGEPGEYLHVNLPVSDITLGIMMHELQHLINAYNNLMQGKSMDIWLNEALSESTSLIFSEPIAKEREYIFNTSTYYSFYTWNLVYTDGTPQGTVPVGGYGNILMSYGSSSIFMKWLDSKTGGKQEIYKEIAHSPSAPTSEQRLMNVLSKHGFANDMDTVLLDWIADINNGVVPGLKLSAIDPTDPKFNINGKIPLLPKSLVVYSTADNPQITTSGRLETRPLGKTGLSVVINNSENQGQNLAAAVIADKANVEELTIKKAANLNSSIKYQRFNLQDREYFIDKVITEEDEKNIKKQ
>NC_017243.1|WP_041177134.1|202902_203382_+|hypothetical-protein
MNKKVKYIIFIISVLIFILGCKNNATNPSTFEELGKYRGTWVADNVYMLDLSNDQFLQSGNGMTIKINSDTDTVIDNIVPISIRHLPDTVDSYYLYISTDDVPPQYLSKITAEGGQVNGAYYKLEFTSHNSLKIYMILQCRAGLNPFNLVIQKADLRSN
>NC_017243.1|WP_041177135.1|203460_204801_-|hypothetical-protein
MKKSYIFLFINFMFIISCGNTITQPSNSGEVIGDITYYDPNNTIIKTYPYNLYDGITGTFVGAEGAFKKIAESANAIIYVEESYVDKGITKEGVISFLREFEKYLPREIEIYGEIPDFDGNGKVIFLMANINTNEATTAMAGYFYQSDLIFGKEGVRGEYLHVNVPTNNDTVGTMMHELQHLINAYNNLMQGKAMDIWLNEALSESTSLIFSEPLIGEREDIFNTSTYYSFYTWKLLYTDNTPEGTVSVGGDDNIFISYASSLMFMKWIDLKTGGKQEIYKEIAHSDPSLTDEERLMSVLSKYNLGNDMNDVLLNWIEGINNGDIPGIKLSAIDPDDQKFNINGSIPLLPRSIVLYSTADNPQITSGGKLLTRPLGQTGLSAVINTSVNQESYEGIAETADVENLTIKKAANLNSSIKYQRFNLQNRGYFIDKVITEEDEKNIKKQ
>NC_017243.1|WP_014486685.1|205836_207147_-|hypothetical-protein
MKNIYIFLFAILMFIISCNKPTTSPSEPISEIINGITYYDPATAETKEYPFFRIDNVTGQNIFVKNTFKKLAVSKNAIIYLEQGINTITKDKILSFITKFEEYYPREVEIYGQPSDFDGNGKIIFLMANLNTNTAGGSFSTGGYFNPLDLSIGKGGIAGEYLHIDVGNNIDYGIGIMMHELQHLINKYVNGIKKNKAMDIWLDEALSESTSHMFDKEMVNMRAKAFNDTPYYSFYSWYFQYSKNNDIFTKPMYAASYAPVSMFMKWVDAKTGNNQEIYKKIASSSLTDSEQILLDSVKTLAPSLGNDMDTLLINWIKGINNGDIKDISNAPNISDLASSKSYEEFLINGQTQLLPKALIVCSKQDSDKITDSNIRKEDLGNGNYIVLNTRKNASAGFTSASDIVPISLTRTAVRNNNVSELTMFKKDYFTDIVITE
>NC_017243.1|WP_041177136.1|207320_207782_+|hypothetical-protein
MNKKLLSIIMVISSLFFILSCKNNVNNPNVYFQDQPITSYSGTWKGDIYDTLYNEQPLFLATIIINDDGSINYDGDIVAKEDIISKGNNTFEFILYDNLTLGNQIVALRYVNTLKITDNYTMNCFGTIDMKSGVSEEVWDTFMNTSGTLQKQQ
>NC_017243.1|WP_014486687.1|208161_208686_+|hypothetical-protein
MNKKLFSTLFIIVILASFSAIGCKNPNTDPTPTGTDIGEKYAGTWYLNATMKVEFGNPAPQNADQIIAEFAPQLDGTAVKNDQIIINDDGSIKDSAGDIIQKTDIVKEGDKYIVKLKNDYPNLPQDIFPEAGMEITFNADGAGTVATYLVMNLNNNYYNFYLFKDGKLTKNPVQ
>NC_017243.1|WP_041177137.1|208778_210113_-|hypothetical-protein
MKKTYIFLFIIFMFIISCGNKITGPSENIDGITYYDLSHAETKEYPFLKSDVITGAWIDAKSTFNKVAESQNAIIYLEKGYNKMTRDTIMSFVKQFEEYYSKEVEIYGNPSDLDLNGKIIFLMGNLNTNQTKEKPGIGGYFYGSDLTRGKGGVKGEYLHVDPSVANEDYILGVMMHELQHLINFNVNYFNTGKEMDVWLDEGLAESTSHIFSKEISDSRLKSLDKVPYYSFYSWYFKYPIDGSDANIFGTPMDFASYGPASMFMKWLDIKTGGNQEIYKKIAHSSHIKDGEQRVIQCAQELNPSLGTDMNTLLIDWIKGINNGEVPGLSIKNFASTSDNYYNLFLKNGKTLLLPKALIICTAEDANKINDTKIIKEDLKNGNYIVLNTSQNQYAGYSAESDIVSISLTKAAVPNSRYNNITESTIFKDNYFIDRVITEKDIIKK
>NC_017243.1|WP_041177138.1|210211_212065_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MNNNKYDVIVVGAGHAGIEAALSSARLGMKTLIISINLDTIGQMSCNPSIGGVAKGTIVKEIDALGGEMGKLIDKTMMQFRMLNRSKGKAVWAPRAQADKYAYKEEAAKTLYAENNLTLHQDIVTEIIVENNVLKGIRTERGREYECQAVILTTGTFLNGLIHIGKYQKQAGRIGELPAIGLSDSLRSLGLEVGRLKTGTPARVDYYSINFDILEMQKGDDEITPFSFLDEKIDIVQEPCYITYTDANIHKIIQDNIHLSPMYSGVITGIGPRYCPSIEDKVVRFADKPRHQLHLERESYRTNEVYINGFSSSLPEEVQIKMIRSLKGLEEVRILKPAYAVEYDYVNPIELKPTLETKKIEGLFLAGQINGTSGYEEAACQGLMAGINASLKIKKEAPFILKRSDGYIGVLIDDLTTKGTKEPHRMFTSQAEHRMLLRQDNADERLTELSYNIGLASKERLEKVRDKKQKTQILVEYLNKRTLTQKETEDLGFTKEAKEYRTMSLASIIKRPECGIDMIKHLIDGDYNKNVLENAEIAIKYEGYIARYLNEIRDIEKYENMLIPEDFDYSTLKSVKIDAINKLKQYKPYNISQALRIPEVDKSVVHILILALTNKKK

Crispr_ID: NC_017243_2

• CRISPR_ID: NC_017243_2
• CRISPR_location: 260121-260327
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017243_2

Consensus_repeat	Method
TGGGAATAATAAAGATTTAGAGGATCTTTATTGTT	PILER-CR
GAATAATAAGATTTAGAGGATCTTTAT	CRISPRCasFinder

spacers of NC_017243_2

>2.1|260156|52|NC_017243|PILER-CR
TCCAAGGCGTTAGAACCTTTAAGCTTAATTCTAACGGACTATAAAAAATCAG
>2.2|260243|56|NC_017243|PILER-CR
CTCCGTAAAAACAGTAACTAATAGGAAAGTTATGCTGCTTTTACTAGTGTAGTAGT
>2.3|260150|59|NC_017243|CRISPRCasFinder
TGTTTCCAAGGCGTTAGAACCTTTAAGCTTAATTCTAACGGACTATAAAAAATCAGTGA
>2.4|260236|61|NC_017243|CRISPRCasFinder
TCTCCGTAAAAACAGTAACTAATAGGAAAGTTATGCTGCTTTTACTAGTGTAGTAGTTTGG

CRISPR arrays and Neighbor proteins around NC_017243_2

CRISPR arrays

The CRISPR arrays of NC_017243_2

>merge|NC_017243|2|260121-260327|PILER-CR,CRISPRCasFinder
GAAACAACAAAGATTTAGAGGATCTTTATTGTTTCCAAGGCGTTAGAACCTTTAAGCTTAATTCTAACGGACTATAAAAAATCAGTGAGAATAATAAGATTTAGAGGATCTTTATTCTCCGTAAAAACAGTAACTAATAGGAAAGTTATGCTGCTTTTACTAGTGTAGTAGTTTGGAATAATAAGGATTTAGAGGATCTTTATCGTT

>NC_017243|2|1|260121-260327|PILER-CR
GAAACAACAAAGATTTAGAGGATCTTTATTGTTTC	CAAGGCGTTAGAACCTTTAAGCTTAATTCTAACGGACTATAAAAAATCAGTG
AGAATAATAAGATTTAGAGGATCTTTATTCTCCGT	AAAAACAGTAACTAATAGGAAAGTTATGCTGCTTTTACTAGTGTAGTAGTTTGGAA
TAATAAGGATTTAGAGGATCTTTATCGTT

>NC_017243|2|2|260123-260323|CRISPRCasFinder
AACAACAAAGATTTAGAGGATCTTTAT	TGTTTCCAAGGCGTTAGAACCTTTAAGCTTAATTCTAACGGACTATAAAAAATCAGTGA
GAATAATAAGATTTAGAGGATCTTTAT	TCTCCGTAAAAACAGTAACTAATAGGAAAGTTATGCTGCTTTTACTAGTGTAGTAGTTTGG
AATAATAAGGATTTAGAGGATCTTTAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014486724.1|250048_250555_+|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240049
NC_017243.1|WP_014486721.1|246601_247324_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486732.1|262688_263822_-|hypothetical-protein	unknown	unknown	gnl|CDD|368488
NC_017243.1|WP_041177144.1|257350_258493_-|cell-surface-protein	unknown	unknown	gnl|CDD|368488
NC_017243.1|WP_014486727.1|254569_256729_+|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl|CDD|273193
NC_017243.1|WP_014486725.1|250581_252885_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|370539
NC_017243.1|WP_014486740.1|271842_272175_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NC_017243.1|WP_014486738.1|269359_271498_-|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_017243.1|WP_041177552.1|265716_266832_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|336785
NC_017243.1|WP_041177147.1|264221_265397_-|cell-surface-protein	unknown	unknown	gnl|CDD|368488
NC_017243.1|WP_041177143.1|245961_246387_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177142.1|245290_245851_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177146.1|260675_261755_-|cell-surface-protein	unknown	unknown	gnl|CDD|368488
NC_017243.1|WP_041177149.1|271507_271828_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177148.1|268281_269028_+|DUF3108-domain-containing-protein	unknown	unknown	gnl|CDD|378635
NC_017243.1|WP_014486737.1|269092_269302_-|DUF1858-domain-containing-protein	unknown	unknown	gnl|CDD|274898
NC_017243.1|WP_014486723.1|249132_249939_+|aminopeptidase	unknown	unknown	gnl|CDD|176452
NC_017243.1|WP_041177145.1|258927_260052_-|cell-surface-protein	unknown	unknown	gnl|CDD|368488
NC_017243.1|WP_014486726.1|253217_254396_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|273380
NC_017243.1|WP_014486735.1|266873_267743_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014486724.1|250048_250555_+|NUDIX-domain-containing-protein	gnl|CDD|240049	cd04693, Nudix_Hydrolase_34, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	6.54447e-25
NC_017243.1|WP_041177552.1|265716_266832_-|AAA-family-ATPase	gnl|CDD|336785	pfam07728, AAA_5, AAA domain (dynein-related subfamily). This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.	4.15949e-40
NC_017243.1|WP_014486732.1|262688_263822_-|hypothetical-protein	gnl|CDD|368488	pfam05540, Serpulina_VSP, Serpulina hyodysenteriae variable surface protein. This family consists of several variable surface proteins from Serpulina hyodysenteriae.	9.09216e-137
NC_017243.1|WP_041177144.1|257350_258493_-|cell-surface-protein	gnl|CDD|368488	pfam05540, Serpulina_VSP, Serpulina hyodysenteriae variable surface protein. This family consists of several variable surface proteins from Serpulina hyodysenteriae.	9.63944e-132
NC_017243.1|WP_014486727.1|254569_256729_+|single-stranded-DNA-specific-exonuclease-RecJ	gnl|CDD|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	4.25552e-58
NC_017243.1|WP_014486725.1|250581_252885_+|AAA-family-ATPase	gnl|CDD|370539	pfam09511, RNA_lig_T4_1, RNA ligase. Members of this family include T4 phage proteins with ATP-dependent RNA ligase activity. Host defense to phage may include cleavage and inactivation of specific tRNA molecules; members of this family act to reverse this RNA damage. The enzyme is adenylated, transiently, on a Lys residue in a motif KXDGSL. This family also includes fungal tRNA ligases that have adenylyltransferase activity. tRNA ligases are enzymes required for the splicing of precursor tRNA molecules containing introns.i.	1.51325e-32
NC_017243.1|WP_014486740.1|271842_272175_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.85425e-14
NC_017243.1|WP_014486738.1|269359_271498_-|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.02039e-06
NC_017243.1|WP_041177147.1|264221_265397_-|cell-surface-protein	gnl|CDD|368488	pfam05540, Serpulina_VSP, Serpulina hyodysenteriae variable surface protein. This family consists of several variable surface proteins from Serpulina hyodysenteriae.	1.32913e-147
NC_017243.1|WP_014486737.1|269092_269302_-|DUF1858-domain-containing-protein	gnl|CDD|274898	TIGR03980, conserved_hypothetical_protein, hybrid cluster protein-associated redox disulfide domain. Members of this protein family resemble the domain of unknown function DUF1858 described by pfam08984, but all members contain an apparent redox-active disulfide. In at least one member protein, a cysteine in the CXXC motif is substituted by a selenocysteine. Most member proteins consist of this domain only, but a few members are fused to or adjacent to members of the hybrid-cluster (prismane) family or the nitrite/sulfite reductase family. [Energy metabolism, Electron transport].	1.3568e-20
NC_017243.1|WP_041177146.1|260675_261755_-|cell-surface-protein	gnl|CDD|368488	pfam05540, Serpulina_VSP, Serpulina hyodysenteriae variable surface protein. This family consists of several variable surface proteins from Serpulina hyodysenteriae.	1.63858e-154
NC_017243.1|WP_041177148.1|268281_269028_+|DUF3108-domain-containing-protein	gnl|CDD|378635	pfam11306, DUF3108, Protein of unknown function (DUF3108). This is a bacterial family of putative lipoproteins. Structure 3fzx, the first structural template for this large family including several homologs in the human gut microbiome and in metagenomic datasets, folds into a beta barrel that topologically looks like a small-scale porin (such as FepA). Bacteroides fragilis glyA is a putative exported protein, and this fold is of the YmcC-like type, with a predicted signal peptide SpI cleavage site AGAMA|QNQDC, and a Phobius server prediction of non-cytoplasmic localization for amino acids 21-236. The possibility of it being a membrane protein can be ruled out by the hydrophilic nature of the solvent exposed surface outside the barrels. Analysis of sequence conservation suggests that an area near Glu172/Trp206 is potentially interesting. These two residues are also conserved in Dali hit Structure 2in5, a hypothetical lipoprotein classified as a new YmcC-like fold in SCOP (SCOP:159271, with a 12-stranded meander beta-sheet folded into a deformed beta-barrel) despite large structural differences between the two structures, suggesting similarity in function.	9.06377e-13
NC_017243.1|WP_014486723.1|249132_249939_+|aminopeptidase	gnl|CDD|176452	cd08770, DAP_dppA_3, Peptidase M55, D-aminopeptidase dipeptide-binding protein family. M55 Peptidase, D-Aminopeptidase dipeptide-binding protein (dppA; DAP dppA; EC 3.4.11.-) domain: Peptide transport systems are found in many bacterial species and generally function to accumulate intact peptides in the cell, where they are hydrolyzed. The dipeptide-binding protein (dppA) of Bacillus subtilis belongs to the dipeptide ABC transport (dpp) operon expressed early during sporulation. It is a binuclear zinc-dependent, D-specific aminopeptidase. The biologically active enzyme is a homodecamer with active sites buried in its channel. These self-compartmentalizing proteases are characterized by a SXDXEG motif. D-Ala-D-Ala and D-Ala-Gly-Gly are the preferred substrates. Bacillus subtilis dppA is thought to function as an adaptation to nutrient deficiency; hydrolysis of its substrate releases D-Ala which can be used subsequently as metabolic fuel. This family also contains a number of uncharacterized putative peptidases.	2.16895e-121
NC_017243.1|WP_041177145.1|258927_260052_-|cell-surface-protein	gnl|CDD|368488	pfam05540, Serpulina_VSP, Serpulina hyodysenteriae variable surface protein. This family consists of several variable surface proteins from Serpulina hyodysenteriae.	9.7208e-151
NC_017243.1|WP_014486726.1|253217_254396_-|tetratricopeptide-repeat-protein	gnl|CDD|273380	TIGR00990, Mitochondrial_import_receptor_subunit_TOM70, mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70). [Transport and binding proteins, Amino acids, peptides and amines].	4.58248e-18
NC_017243.1|WP_014486735.1|266873_267743_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.08624e-08

Protein sequences

>NC_017243.1|WP_041177145.1|258927_260052_-|cell-surface-protein
MKKVLLTAMALLTIASASAFGMYGDRDSWIDFLVHGNQFRARMDQLGFTLGNGTIKGTFGFRSQAATTYLGNILSGGTGAVDLTTTISAGIGYTSEPFGIGVGYSYTHLHDRLGVHTPVLMINALNNNLRIAVPIQIATSSNPFNNVLGLNTEKDYMGVSTDIQIRYYTGIDAFNAIRVYFRYGQAGYKNGTTDMFAQSIGFQTRFYFLNTTVGNVGINPYLKVEFDTALVGDNKTVRAGEAAYDSQNKVFNSGSFAINSGTGKQEWEKTPYKVTAAAVLGITANSDIVSLYVEPSLGYTAEAGGKQKGAINDPTVTHKLAWGAYTELYVRPVQDLEWYFEMDVNNNTGAANYNNVPVNFAASTGITWYLPALN
>NC_017243.1|WP_041177144.1|257350_258493_-|cell-surface-protein
MKKILVTAMALLTIASASAFGMYGRGDGWIDFLVHGNQLRARMDQLGFVLGNATIKGTFGFKAEGNYWGQILSGQTDNIYLLPSISGGIGYTSEMIGIGVGYSYTMAKDYLGGYIGVHTPVLMVNALNNNLRISIPIQVAVKEYSLGNVKETYTGVAFDNIQLRYYTGIDAFNAIRVYFYYRNSTFRYNNDASKYSTSEIFGFQTRFYFLNTTVGNVGINPFVRVDFHTVLKGGVNNGEYIYKAEDVGNGRFVSGTVKQSDYYAKNPYKVSAQVALGITANSDIVSLYVEPSLGYTGNYAGQANTISTDGTITKGPDPKVEHKLAWGAYTELYIRPVQDLEWYFEMDVNNSGTKQNSGIPVYFETTTGITWYLPALNGAQ
>NC_017243.1|WP_014486727.1|254569_256729_+|single-stranded-DNA-specific-exonuclease-RecJ
MDINNLNTTILELLKLRGITSKEDIYDFFFQDIYSLSNPFNIRDVNVFVDRVKEAIENDEKILVYGDKDADGITAASIIYNTLKVVTKNVEAFVPNHTTGYGLSKAVIEEYANSGVSLIITVDCGISNAEEVEFARDLSIDIIVTDHHDIPEILPNAYAVFNPKISNTGFVSKNFSGCAVAFKLMQAFVFSYTKLYNKDIIVLDYEIDKSKNVLKRIRALKSTNFVISDEVFGFELINDNNCYKSIYADYYDELMSEDEVLEELATYMFEGDGCVLVLTGGEERLKKLLNFYERYEIYLPEYDNVYDLLQLGAKYGNVNIKTTKTLDDFALALNVNIYRYDDIAYRDLIIKMEIFRRLFYISQKQLQSYIKKKSILVLFGSVADVVPLIEENRAYVKCALKELEKPSHIRYNIILERINLLNTKIDTQAISWRLAPFINAAGRMGSPETALKLLTCEIKEEAVTLSNEVYNMNETRKSLTESNFTIVNEYIKTNSCLKLPIIVVKSKKIEQGLTGLIAGKVLSEYGKTAVIMHESDDGVCIGSIRSRGEDNARDMLDYANAYLTKFGGHKNAAGFTLNTDNFDKFQSKIIKYASSQNFQTEKNEDEFDLELSFKDIDIKLAKLLEMFEPYGCGNEEPLFMSKKVKVNSINKMKKNNKTHLRLELLQDNKKVNAIMWDKSDDEADKLLSSDYIDIIYKLKVNRFNGSEDARIYVESYKIF
>NC_017243.1|WP_014486726.1|253217_254396_-|tetratricopeptide-repeat-protein
MAEKDIKNFFNKAYDAFKSKNYKLAIEYFSEVIKLDSTIYEAYYNRANAKANINNEDSYKSAVEDYTWTIKLNDKFAAAYYNRGIINRSLGNSEEALKDFDKTIELNYNLEEAYYVRANTKASLKDYKGSIEDYNKAIEVYPHFADAYYNRALSKNALSEYKEAIKDYDKAIEYNSHFIDAYNNRGNVKEKLGNFNEAIDDYTNAIHINREFADGYFNRANAKFHIKDYKGAVEDFDELIKINPKYTKAYLNRGIIAMTMGAYQEAIKDFDKAIELDSNIADAYYNKAVALNHLGIYDEAILYYDQAIKLNPNYSESYFNRGISKSKTAYMKKEKINEDEYNKLVKESEDDFDKAYDLANEHIKHIISEGLKKLAFLNMEAADNFCKKHDIK
>NC_017243.1|WP_014486725.1|250581_252885_+|AAA-family-ATPase
MKVLILTVGPQGSGKSYTIKKANLDYYSVSSDNLRILYSGVFPDGYNGLEISEKDNAYIWNNLILSILENRFRLGQFTILDSTGLFNLNSITELAKKYGYRIVAVLFDHLSLKECIENVRKRGVGSNIPEEVIQDFFMRMKNFKLSGANIFKASDYGSAETALLEACKWDSFYLNETEFEKYDNIKVIPDLHGEYDVFKKFLEKENYFNDKKTAYIFVGDLIDRGVKSKELLDYFLNNDIGNNVYFIEGNHDVNLNFFANDIKVTSQEFYKTTYKEIKKAFTITKQVKDNSDNVVEEKILNESELNNYKKKIRNFYKKFRLYYFFTFKGKKFFINHSGIDKMYEHIPASLLNGVVTYGYGEDDNSYKSYIEVGNKFKNNHSDIIQIFGHRNVLQEELEDNLCKINDNAYCIENSVEYGEDLIILNLKYMSIESYKNDREIENLFDKEKTDSELVRHKYYDTVYSTNFSDRVFYKRLWNEQTIKARGLYRYNETNEIAGRSYDKFFNYDEVKETKLKALQNNIKFPVSVYKKYNGYLFLVFLDKTRDELIFATKSSIGTTMASWAESLLTEENKNFIKEYCKKNNTTFVFECIHLKDSAHPIVYNESFLILLDIIYNEESFRKLSYEELSSKDITEQFQVKERIEIFEAPKSNISKDEYNKYIEKIIHKYVDDFSIDYEGVVFEDANCFMVKVKCPFYIIKKALRSESMRLNRLSYSLNIHYPNNHVIFVGNKIFLKYKRENSLKEWRSLEVSEVVEAYNEVLKELGK
>NC_017243.1|WP_014486724.1|250048_250555_+|NUDIX-domain-containing-protein
MKEIWDIYDINKNKTGRFHQRGIPLKKNDYHIVIHAWVVNSNDEVIITKRHKSKKVCPNMWECTEGSILAGEDSADGALRELQEEIGLSFKKDEAVFLTSFVLEFSNTIVDSYMFRRDVNIEDLVLQENEVSDAMIVNREKYLEMCKSGEIISSIRYFYDIYDKLNNK
>NC_017243.1|WP_014486723.1|249132_249939_+|aminopeptidase
MKVFISADIEGITTTTQWPDTDAGSLTYKEHTLQMTKEVNAACEGAIDAGAKEIFVKDAHDSAMNIDQTALPECVKIHRRWSGDPYSMIEGIDESFDAIMFIGYHNAASIGNNPLSHTMNTRNVYVKLNEVLASEFMFFSYAAAYRKVPTVFLSGDKGLCEVAQNMQPNHPNLVTLPVKEGIGYSTINYSPNLMVKMIKEKTKEALSQDFKGKLLKLPNTFKLEVCYKEHGYAHKVSFYPGAKKINDTTVIFENNDYYEILRALKFIL
>NC_017243.1|WP_014486721.1|246601_247324_+|hypothetical-protein
MKKILLMILIVSVLAIGCKDNVTNPMEYMVERGSDWTSRANVRANEKIYFGPIYIVNNKHVYVTSAKIIQVDKTTSITNDIPSVTEKDERGYITSITPLESQSSGSIAYIVFTYKNTLVSASFLEEYLYKYSGEIYSNTWFEIYNENMQVAEIVIVKEITVTRKVYDDQGQYIDTVSGTFSGEKTFEVIESPSTPGKIYIMLNPSYLNFKNEDGQYYIAPYPNYINYKDIEIEIVYTIIH
>NC_017243.1|WP_041177143.1|245961_246387_-|hypothetical-protein
MYKIYSAFIIIMLFIISCNDKKLESKQYRLNISETNEVINIKSRNFDGISLIKNSSFTAYPNITINELLSPFSSVEWQDFISEDDYNRYIDIVARYDTNEYIIQFQITDQYRWELYAFEINKTPYTIDIVANELYKLYTNK
>NC_017243.1|WP_041177142.1|245290_245851_+|hypothetical-protein
MIKKIFIAVVLMNILVGCVTMQPKDNNNTATKDNAVTKDDTANNEDKKEETITREDTPKMKVTVYGADKEIQAVEINDKVYYVIGGKDVEDMTEAEIKKSSLVAPLKITEETINGTKGIVVTYYDVKVFLGKRTGTGTTVGIFEPQKNDWTTGNDIDRSLSIQIKLSRNIAGPIDIKRGSISLAFN
>NC_017243.1|WP_041177146.1|260675_261755_-|cell-surface-protein
MKKILLTAMALLAMAGASVFGMYGDQDDWIDFLTDGNQLRARMDQVGFVLGNNTIKGTFGLRSQAVGTLLGNIISGQTDNIGLDATISAGIGYTSEPFGIGVGYNFTYYNSTLGVHTPVLVMNALNNNLRIAVPVQVAVSKEPFGKGTGNNWKDYLGVSTDIQIRYYTGIDAFNAIRVYVKYGQSGYKEVQNNMDMFQQSVGFETRFYFLNTAIGNVTVNPFVKVAFNTALVGNNTMVRAGEAIYSIYAQKDIKWDKNPYDITVAAVLGITANSDIVSLYVEPSLGYQATYEGKYKTDTVDPKVIHNLAWGAYAELYITPVQDLEWYFEMDVNNSNSDGSNVPVSFAATTGITWYLPEF
>NC_017243.1|WP_014486732.1|262688_263822_-|hypothetical-protein
MKKVLLTAIALLTIASASAFGMYGRGDSWIDFLVHGNQFRARMDQIGFTLGNGTIKGTFGFRANAINLGNLGNILSGSTGNVKLDSTISAGIGYTSDMIGIGLGYNYTFANDSINGGYIGVHTPVLMVNALNNNLRISIPIQVAVKDYNNVLSYTGKTTYTGVAFNNIQLRYYTGIDAFNAIRLYFYYRNSSITREGSDYSQVSEAFGFQARFYFLNTQIGNVTVNPYLKVAYNTALQGGTIGDYTAETFVSPLTVNDGINKFKQSDVYEANAYNVTAAAVLGITANSDIITLYVEPSLGYTASYAGRPKGAVDPKVNHKLAWGAYTELYIRPVQDLEWYFEMDVNNGANTQSTGVPVYFETTTGITWYLPDLGGAQ
>NC_017243.1|WP_041177147.1|264221_265397_-|cell-surface-protein
MKKFLLTVMAILTIASGSVFGMYGADNTWLFFLIHGNQFRARMNQLGFTLGNGTIKGTFGFKANTLINGSILNTGGKGNKSPLEATISGGIGYTGDGFGIGVGYNYTYSATGTGINTHTPVVTMNFLNNNLRIALPISVAVENSIGGTVDANGNTVLSERKDYLGLSIPAQIRYYTGIDAFNYIRFELNYGLNRYNGTYGANTTSKFEAQSISFQLRLHFLNTVIGNNVTVNPFLRIDFGSTIGAKGKSVLASSALLPGGFDQRFTAWAASGWREATASEEAYDREAYDLKIIPSISLSVNTDIINLIFEPGLGYRVQDDGRKGSKLSHTLYWQAYGEIYIRPVQDLEWYFEMDVNNGVPKLQGNPIASGNNIPVVFGANTGITWYLPALQ
>NC_017243.1|WP_041177552.1|265716_266832_-|AAA-family-ATPase
MKKDNINNEEKIHQKPLMEELYKEELEALKNEDKNSKPKNWNLSPQAVRDFILGKKLKSGVEIKRKFYGDDALVERAIITLAGNRGLMLVGEPGTAKTMLSELLSAAISGNSTVTIQGTAGTNEDNIKYSWNYAMLFAKGPVEEALIPSPVYIGMNQGIITRFEEITRCPLEIQDSLISILSDKIMNIPEQNRVLFANAGFNIIATANTRDKGINEMSSALKRRFNFETVEPIKNPKLEGEIITNQCQTLLELSDIDIDIDYDVVDILATTFNELRSGKSFENAKIQELNSVMSTAEAVSVYYQSALHSYYYGDKNIKMDTVVGNLIGSVAKENKDDLPKLKNYFNNSVKIKAEKLGKRWKEYYESRNLIK
>NC_017243.1|WP_014486735.1|266873_267743_-|DMT-family-transporter
MAIFLLIGVMALSASAIFVKLANAPSSIIAFYRIFISFCFISVITISKKSSREELLSISRKEIILSIISGLSLALHYFLWFQSLSLTSVASSTVIVTLQPLFAFVAGHFFFKEQYSKLAILGFVIAVMGSVIIGWGDFQISSKALLGDFIAFISAGLISTYFIIGQYTRKRLSALTWISLTYFSAFIFLGILSYIMKIPFIGYSLNTWINILGITFISTMLGQVIFTWLLKYFSATIISMTILGEAVGTCILGYFILHESISFKQFIGIAVILIGIGLFLWEKRKTISQ
>NC_017243.1|WP_041177148.1|268281_269028_+|DUF3108-domain-containing-protein
MKKYIFIIMALISNIVFGYNQTFKVGEYIKYDVLAQVPEFNISGKVGILEAKVLAISNVNGVPAYHLYAHVYTTGAANWVYKVSDIFEAWVTTNDFKPIILKKDTSEGDWTNKESLTFYNNYYLFNDKRTVDEKVEFEGMAFDALSLVFFMRFVDKNIGTFKVNWLEGKNVKKDIRFTIENGEDLKTKLERDKLSTIRIYEKDKYGTDALIAKDKYNQVPLDVIIAEQKVYGLTIRVRGIIREYKDGK
>NC_017243.1|WP_014486737.1|269092_269302_-|DUF1858-domain-containing-protein
MINKSMSIGEIIQIFPDSVEIMMGRGLHCVGCHVASWESLEEGCRGHGMSDEVIDSIVKEINDKLEASK
>NC_017243.1|WP_014486738.1|269359_271498_-|hypothetical-protein
MSSLDEISKYIDDGDYKKAIEELDLIISREPDNARAFYMRGKSAFIELQNEEFDKNKYDARRALIYATIEYDLNKSIDIDPNIIDAYRGLMYLNRDLKNVDKEREYAQILFEKDNTAYDALLILASSYLNNGENEADFHQAIGYYDDFIKNVKPENSKVARFERGLCYYNLNILTKADIEANKLIYDFPFYDDAYFLKGIILAKNGTKSEFYDDAIFFLDRAVELNASNYNAIYERAEWYFNKENYRKAIENYNELLKHNNKYRLNALLGKIQALHDLIIENENEHYPDSQEEGKDLAEVFYLLDKVIDVIGIKSLQYRYYRGNLYAYQGEIKKAITEFKKILNENKEAWIYEKIAELYHNYAKNDDDYKEALKYLSHIDKIEYKYSTYYLSIFSNYEIKNYEAAAQLCREFFEYVNDNDDEVYYIRFIYAHSLQMIGSNDYKLILDNFKACLNSNLDKAPIYRSIAKIMLFNMPNEYINEGIYMLKKALELNDAISYHIYAKELFYGDIITPYPELAISMANIAFDIDNTLECALTVIGKAYELGRGIEQDEFKAFETYSKAMTICQNSNSKCSCSNGLIAHCYYKGIGVEKNEEMAYDIIKTTVDALGNNSHDYVALLYSYFALNNIEGFDLVTSLTLFENIENYSHNIYIIMILKRIYKRLKKHNDVRRMAKMEKKALENTGELNLNYIRKYIKNFNDFYPILNKDFTL
>NC_017243.1|WP_041177149.1|271507_271828_-|hypothetical-protein
MLIETIRFIYYLLMQTLRLYSFIWFVWIILSWLQAFGAMHLDYYNPIVNFFYQITDGIIDKIFGGRRLIVGVLDLSPLVFLLVLQLVVPIILRVIFQFLLNIVARI
>NC_017243.1|WP_014486740.1|271842_272175_-|STAS-domain-containing-protein
MVRTIIEDKTAIINIEKNIISENVDILEEKLNYVKNAGVLNLIFDFHNIEYMCSSALGLIASALRLSGENGGVVYFCSLSKQLKSLFEATKFLTIVNTADNIDEALKNIK

Crispr_ID: NC_017243_3

• CRISPR_ID: NC_017243_3
• CRISPR_location: 316960-317186
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017243_3

Consensus_repeat	Method
AATAGGCTCATAATTTTTTCTTATATCCTTTATAAAAAATTTGTTCGTTAATAAGCCC	PILER-CR
TTTCTTATATCCTTTATAAAAAATT	CRISPRCasFinder

spacers of NC_017243_3

>3.1|317019|52|NC_017243|PILER-CR
TGCCATTCTAACGAATGTCAGGCACTCACAAATTTTTTATTATAGTTTTTCT
>3.2|317130|32|NC_017243|PILER-CR
ATTCGCTTCTAGGCTATTTTAAGTAAACTTAA
>3.3|317097|48|NC_017243|CRISPRCasFinder
ATTCGCTTCTAGGCTATTTTAAGTAAACTTAAAATAGGCTCATAATTT

CRISPR arrays and Neighbor proteins around NC_017243_3

CRISPR arrays

The CRISPR arrays of NC_017243_3

>merge|NC_017243|3|316960-317186|PILER-CR,CRISPRCasFinder
AATAGGCTCATAATTTTTTTCTTATATCCTTTATAAAAAATTTGTTCGTTAATAAGCCCTGCCATTCTAACGAATGTCAGGCACTCACAAATTTTTTATTATAGTTTTTCTATTTCTTATATCCTTTATAAAAAATTATTCGCTTCTAGGCTATTTTAAGTAAACTTAAAATAGGCTCATAATTTTTTCTTATATCCTTTATAAAAAATTTGTTCGTTAATAGGCCC

>NC_017243|3|2|316960-317186|PILER-CR
AATAGGCTCATAATTTTTTTCTTATATCCTTTATAAAAAATTTGTTCGTTAATAAGCCC	TGCCATTCTAACGAATGTCAGGCACTCACAAATTTTTTATTATAGTTTTTCT
ATTTCTTATATCCTTTATAAAAAATTATTCGCTTCTAGGCTATTTTAAGTAAACTTAAA	ATAGGCTCATAATTTTTTCTTATATCCTTTAT
AAAAAATTTGTTCGTTAATAGGCCC

>NC_017243|3|3|317072-317169|CRISPRCasFinder
TTTCTTATATCCTTTATAAAAAATT	ATTCGCTTCTAGGCTATTTTAAGTAAACTTAAAATAGGCTCATAATTT
TTTCTTATATCCTTTATAAAAAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014486791.1|328078_328510_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379279
NC_017243.1|WP_014486780.1|315690_316806_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226962
NC_017243.1|WP_014486776.1|311462_312122_+|diphthine--ammonia-ligase	unknown	unknown	gnl|CDD|238952
NC_017243.1|WP_014486778.1|314032_314305_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486775.1|310883_311396_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NC_017243.1|WP_041177159.1|323149_324232_-|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380577
NC_017243.1|WP_014486774.1|310399_310666_-|YtxH-domain-containing-protein	unknown	unknown	gnl|CDD|378938
NC_017243.1|WP_014486771.1|307976_308870_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486787.1|324278_325064_-|nucleoside-phosphorylase	unknown	unknown	gnl|CDD|350167
NC_017243.1|WP_014486770.1|307229_307967_+|site-2-protease-family-protein	unknown	unknown	gnl|CDD|100079
NC_017243.1|WP_014486790.1|326798_327917_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl|CDD|99740
NC_017243.1|WP_041177156.1|318110_319640_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226364
NC_017243.1|WP_041177158.1|322032_323106_-|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380577
NC_017243.1|WP_014486772.1|308893_309958_-|hypothetical-protein	unknown	unknown	gnl|CDD|131971
NC_017243.1|WP_041177157.1|319795_320875_-|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380577
NC_017243.1|WP_014486788.1|325082_325901_-|nucleoside-phosphorylase	unknown	unknown	gnl|CDD|350167
NC_017243.1|WP_014486784.1|320942_322019_-|BMP-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380577
NC_017243.1|WP_014486779.1|314705_315659_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224005
NC_017243.1|WP_014486773.1|309983_310391_-|DUF948-domain-containing-protein	unknown	unknown	unknown
NC_017243.1|WP_014486789.1|325955_326606_-|deoxyribose-phosphate-aldolase	unknown	unknown	gnl|CDD|234784

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014486791.1|328078_328510_+|ATP-binding-protein	gnl|CDD|379279	pfam13581, HATPase_c_2, Histidine kinase-like ATPase domain.	9.10693e-19
NC_017243.1|WP_014486780.1|315690_316806_-|ABC-transporter-permease	gnl|CDD|226962	COG4603, COG4603, ABC-type uncharacterized transport system, permease component [General function prediction only].	8.6985e-81
NC_017243.1|WP_014486776.1|311462_312122_+|diphthine--ammonia-ligase	gnl|CDD|238952	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins is predicted to bind ATP. This domainhas a strongly conserved motif SGGKD at the N terminus.	2.50966e-59
NC_017243.1|WP_014486790.1|326798_327917_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	4.86153e-121
NC_017243.1|WP_014486775.1|310883_311396_+|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	2.76788e-19
NC_017243.1|WP_041177159.1|323149_324232_-|BMP-family-ABC-transporter-substrate-binding-protein	gnl|CDD|380577	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. The PnrA lipoprotein, also known as Tp0319 or TmpC, represents a novel family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC) transport system (pnrABCDE). It shows a striking structural similarity to another basic membrane lipoprotein Med which regulates the competence transcription factor gene, comK, in Bacillus subtilis. The members of PnrA-like subgroup are likely to have similar nucleoside-binding functions and a similar type 1 periplasmic sugar-binding protein-like fold.	5.39916e-66
NC_017243.1|WP_041177158.1|322032_323106_-|BMP-family-ABC-transporter-substrate-binding-protein	gnl|CDD|380577	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. The PnrA lipoprotein, also known as Tp0319 or TmpC, represents a novel family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC) transport system (pnrABCDE). It shows a striking structural similarity to another basic membrane lipoprotein Med which regulates the competence transcription factor gene, comK, in Bacillus subtilis. The members of PnrA-like subgroup are likely to have similar nucleoside-binding functions and a similar type 1 periplasmic sugar-binding protein-like fold.	1.12373e-55
NC_017243.1|WP_014486787.1|324278_325064_-|nucleoside-phosphorylase	gnl|CDD|350167	cd17767, UP_EcUdp-like, uridine phosphorylases similar to Escherichia coli Udp and related phosphorylases. Uridine phosphorylase (UP) is specific for pyrimidines, and is involved in pyrimidine salvage and in the maintenance of uridine homeostasis. In addition to E. coli Udp, this subfamily includes Shewanella oneidensis MR-1 UP and Plasmodium falciparum purine nucleoside phosphorylase (PfPNP). PfPNP is an outlier in terms of genetic distance from the other families of PNPs. PfPNP is catalytically active for inosine and guanosine, and in addition, has a weak UP activity. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	1.62955e-112
NC_017243.1|WP_014486770.1|307229_307967_+|site-2-protease-family-protein	gnl|CDD|100079	cd06158, S2P-M50_like_1, Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the S2P/M50 family of RIP proteases use proteolytic activity within the membrane to transfer information across membranes to integrate gene expression with physiologic stresses occurring in another cellular compartment. In eukaryotic cells they regulate such processes as sterol and lipid metabolism, and endoplasmic reticulum stress responses. In prokaryotes they regulate such processes as sporulation, cell division, stress response, and cell differentiation. This group includes bacterial, eukaryotic, and Archaeal S2P/M50s homologs with a minimal core protein and no PDZ domains.	5.91158e-48
NC_017243.1|WP_041177156.1|318110_319640_-|ABC-transporter-ATP-binding-protein	gnl|CDD|226364	COG3845, COG3845, ABC-type uncharacterized transport systems, ATPase components [General function prediction only].	0
NC_017243.1|WP_014486772.1|308893_309958_-|hypothetical-protein	gnl|CDD|131971	TIGR02925, hypothetical_protein_Nmul_A0241, peptidyl-prolyl cis-trans isomerase, EpsD family. Members of this family belong to the peptidyl-prolyl cis-trans isomerase family and are found in loci associated with exopolysaccharide biosynthesis. All members are encoded near a homolog of EpsH, as detected by TIGR02602.	0.00381507
NC_017243.1|WP_041177157.1|319795_320875_-|BMP-family-ABC-transporter-substrate-binding-protein	gnl|CDD|380577	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. The PnrA lipoprotein, also known as Tp0319 or TmpC, represents a novel family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC) transport system (pnrABCDE). It shows a striking structural similarity to another basic membrane lipoprotein Med which regulates the competence transcription factor gene, comK, in Bacillus subtilis. The members of PnrA-like subgroup are likely to have similar nucleoside-binding functions and a similar type 1 periplasmic sugar-binding protein-like fold.	5.02589e-67
NC_017243.1|WP_014486788.1|325082_325901_-|nucleoside-phosphorylase	gnl|CDD|350167	cd17767, UP_EcUdp-like, uridine phosphorylases similar to Escherichia coli Udp and related phosphorylases. Uridine phosphorylase (UP) is specific for pyrimidines, and is involved in pyrimidine salvage and in the maintenance of uridine homeostasis. In addition to E. coli Udp, this subfamily includes Shewanella oneidensis MR-1 UP and Plasmodium falciparum purine nucleoside phosphorylase (PfPNP). PfPNP is an outlier in terms of genetic distance from the other families of PNPs. PfPNP is catalytically active for inosine and guanosine, and in addition, has a weak UP activity. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	2.53963e-125
NC_017243.1|WP_014486784.1|320942_322019_-|BMP-family-ABC-transporter-substrate-binding-protein	gnl|CDD|380577	cd06354, PBP1_PrnA-like, periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea. The PnrA lipoprotein, also known as Tp0319 or TmpC, represents a novel family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC) transport system (pnrABCDE). It shows a striking structural similarity to another basic membrane lipoprotein Med which regulates the competence transcription factor gene, comK, in Bacillus subtilis. The members of PnrA-like subgroup are likely to have similar nucleoside-binding functions and a similar type 1 periplasmic sugar-binding protein-like fold.	3.94941e-70
NC_017243.1|WP_014486779.1|314705_315659_-|ABC-transporter-permease	gnl|CDD|224005	COG1079, COG1079, Uncharacterized ABC-type transport system, permease component [General function prediction only].	2.23005e-84
NC_017243.1|WP_014486774.1|310399_310666_-|YtxH-domain-containing-protein	gnl|CDD|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	1.77137e-14
NC_017243.1|WP_014486789.1|325955_326606_-|deoxyribose-phosphate-aldolase	gnl|CDD|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	6.77047e-127

Protein sequences

>NC_017243.1|WP_014486780.1|315690_316806_-|ABC-transporter-permease
MDFKNKLAGILEKEGFVNIFSSFLAIIIGLLLGLIILLISNVHDAFPAFMTILSGGFSGGSRGMGQVIYTATPLILTGLSVGFAFKNGLFNIGAPGQFIVGAYAAVLVAVKCTFLPPALHWFVALIVSFIAGGLWAYLPGFLKAHFNVNEVISSIMMNYIGMYLVNYLVTLTVYDMLKNQSQNIPPSSMIPTMGLNVIFRGSSANGGFFIAVIVVIIVYIILSKTTFGFELKACGLNKDASKYAGINEKRNIVLSMVIAGALAGLGGGLLYLSGVGKHIEVVDILAEEGFMGIPIALLGLSHPIGILIAGLFIAHITVGGFYMQIYDFTPEIIEMIISSIIYFSAFALLFKSIVGFISKKLIKKEEKNANE
>NC_017243.1|WP_014486779.1|314705_315659_-|ABC-transporter-permease
MDTIYFLVQQTMFFSIPLLLVALGGMFSERSGVVNIALEGIMIIGAFAGIFFISRLGANFPPMITLFLAMIISALSGLIFSLLHAYAAISMSADQVISGTALNIFAPAFAIYVTRAIQTVQQISFVNNFRIESVPILGSIPIIGGLFFKNTYITTYIGFIILALSWFVLYKTRFGLRLRSCGEHPQAADSVGINVYKMRYIGVAISGALGGLGGLVFVIPTSTNFNATVAGYGFLALAVLIFGQWKPMKILYAAFFFGLMKTLASAYSGIPILANLPISNNIYKMIPYITTIIVLAFTSKNSQAPKASGIPYDKSVR
>NC_017243.1|WP_014486778.1|314032_314305_-|hypothetical-protein
MANYEELNNLMENIDHQILFDNALKINELLKDDILLDDMMSENLFVYYFELLEMIKSNPESYQISDIDNDEKIKAINSIIRKMELSFIEF
>NC_017243.1|WP_014486776.1|311462_312122_+|diphthine--ammonia-ligase
MNKKFVMSYSGGKDSTLALYKMIKDGYIPKYIMTTINEEDEHSWFHGISKKLFYEVSKCLDIPHIAINTTHYTYRVNFIEELKKVKEEGINICAFGDIDIQMHRDWAENLCKESGFESKFPLWHQSRISLAREFVDAGFKSKIKIIDTSKLDKKYLGLDFTNELIEEFISIGIDPAGESGEFHTFVYDGPIFKKSLDIKLSEVHDFENHSSIDIICNNN
>NC_017243.1|WP_014486775.1|310883_311396_+|PaaI-family-thioesterase
MELKVLNKQNNSRMCLVCGFKNDLSLKAEFYELEDKSLCALVTFKDVHQGYPSRVHGGILAAILDETIGRAMMPYTGEDKWGVTMTLTTKYKRPVPINKEIRIIGKITSGDGRIFEGEGYILLNDDKVAVTAKGTYICMSLEKIAEMDPNNEEDWAVEKKDTDPTTINIP
>NC_017243.1|WP_014486774.1|310399_310666_-|YtxH-domain-containing-protein
MSKEVSGMFSFLLGLSAGLALGVLFAPKAGEETREDIKETMDNIKYKVDDIYHRSVLKTSELVEKGKERTNDFFEKRKKKTSEETVEE
>NC_017243.1|WP_014486773.1|309983_310391_-|DUF948-domain-containing-protein
MQDITFQINVIAISLAFIAISILILVLAIFFVLLAGYFRFTNRFDRILENIESISEKIGSIADTVNDEANKVKVTLDSIHDSFNSLTNSINNFSSITTDISNNFSIINIFKSIFALFTGKNRKRDDFTENDDEDF
>NC_017243.1|WP_014486772.1|308893_309958_-|hypothetical-protein
MIKRIFFSIFCIVLFSTFLYSQDTNWVIRIRDGEGNIKKLITVEECLSEISNLTVLRGAPENAVNALLTNDFQLWQFASQIIEQEVIYLKAVEEGYDKDEEVLKLIAKERDNQLSQIYMQSKVSDSFAVVTDAEKRKFFNDNISRIRAAVGPNVRYEQVAMEIETTILQERMRNEYDKIIETGKTKYNVKYSMDTDPCVTIEEETVPLSEFNNMFDESIKQAGANIPAALKLQAKEGMFKAFVAREIMMYEAKKEGFYETPQAKSIENFLTRSAVTSHYIDKTIRSTIPTPTEDEINLAYERYGKMYNIDSLPYADAQKALASLVIEAKTQQKYQILVTDLRYRYNIEKILIYY
>NC_017243.1|WP_014486771.1|307976_308870_-|hypothetical-protein
MKNRLSIIYFIFFILFCFSQISFARRNDFDFDVTPLIEKNKMFSVGIGGIFSEYNSWFQSGKLQILDPNNQDISRRDLYFTFMPYFKVRPIKYLELGVSTSFTYQRQDWRNDITSATNMTDEFNFDSINATMKATLLDWYLSIGVKVGLSYSFMKNTHIYSEIKDPFNIYTTIMLAGIPKVIPLNFFFCYTFDTRDNLLKDILNTGEISGGIEIITSPFITLYTGVNYIFPYTKQSSLSYLDIFVKFKATISDFLYMTVSYQKTVYGTGNAPNTSTFNFGIEYMFYTPKGSWWSLNR
>NC_017243.1|WP_014486770.1|307229_307967_+|site-2-protease-family-protein
MVYEIFSNKLSIGIISYVVFIISASTHEYSHARTAFMFGDRTAMRLGRLTLNPLAHIDILGSVVLPIIAAVTGIPVIGWMKAVPVNPNNFNNFERDQALVSFAGPFANLMIATVSFIIMKILTFTVDGTFIIYKIMMFLEHSNNGLSNFMLNALPIVLTMLFMFYMINIMLMFFNLLPFPPLDGGWILRFFLSPKGKDTYDKIYPYGFLILYALLFFGILRTILAFIQTISQHLLGKSINIIFSI
>NC_017243.1|WP_041177156.1|318110_319640_-|ABC-transporter-ATP-binding-protein
MENSEYVVEMLNITKRFKGIVANDNITIQLKRGEIHALLGENGAGKSTLMSVLFGLYKQEEGVIKVNGKEVNIDNPNTANALGIGMVHQHFKLVHNFTALENIMLGVETVKNGILQVDDARKKVMELSKTYGLEIYPDSLISDLTVGMQQRVEILKMLYKDNNILIFDEPTAVLTPSEIEELMKIMKSLTKEGKSILFITHKLNEIKEVADRCSVLRKGKYIGTIDVKSTTKEEMSEMMVGRKVSLVVEKTEAKPKDIILSVKDLNVKSSHSEKNIVKNVSFDVRAGEIVCIAGIDGNGQSELIYALTGLIEMSSGSIHLNGKDITNLSIRNKTLSGIGHIPEDRHKHGLVLDYTLGENTILQTYFTERFQNKGFLKFKEIENYANELIKRFDIRSAEGAKTIARSMSGGNQQKAIIAREIDRNPDLLIAVQPTRGLDVGAIEYIHKELIRQRDNGKAVLLVSLELDEVMNLSDRILVIYEGEIVANVNNKDLTINELGLYMAGSKRSA
>NC_017243.1|WP_041177157.1|319795_320875_-|BMP-family-ABC-transporter-substrate-binding-protein
MKKFLVLIIAVMSFILVVSCGGGGKKSGGYELALITDVGTIDDRSFNQGSWEGLTKYAQEKGISHKYYQPAQKTTDAYVDAIDLAVSAGAKLVVTPGFLFEPAVYRAQDTHPNVSFVLLDGTPQDGTYTDFRIEKNVYSVLYAEEQAGFLAGYAIVKEGYTNLGVMAGMAVPAVIRFGYGFVQGANYAAKELNMPTGSIKINYTYIGNFNATPENQTLATSWYQSGVQVIFAPAGGAGNSVMSAAEQNNGLVIGVDIDQSAESPTVITSAMKMLGESVYNAIDDFYNNKFPGGKSVILDAKVNGIGLPMATSKFQKFTQNDYDTIYQKLNNGSVKVLTDKDAKDVNQLPLDIVKVNLIQ
>NC_017243.1|WP_014486784.1|320942_322019_-|BMP-family-ABC-transporter-substrate-binding-protein
MKKIFSFIIITTAFILMISCSKTTTKEGEFDIALITEGEIDDKSYNQGAWEGLVRYAENSGKSYKYYQATEKTTEAYIDAIDSAVNEGVKLIITPNFLFETAVYKSQDKYPDVNFIIIDGVPQDGTYTDFKLEDNVHAVLYAEEQAGFLAGYSIVKEGYTNLGVIGGMPVPPVIRFGYGFVQGANYAAKELNMPIRSIKINYTYIGNFYDTLQNEELASSWYQNGVQVIFAPAGGAVKSVISAAEQNNGLVIGVDVDQSFESPTIITSAIKRIRNSVYNTVDSFYNGTFKGGEIAVLDATVNGIGLPIKTSQFKNFTENDYNAIYKELSDGNIQVLKDRSVKTVEELPVDIVEINYIK
>NC_017243.1|WP_041177158.1|322032_323106_-|BMP-family-ABC-transporter-substrate-binding-protein
MNKFLTFFIMIVFLYAVSCNDIDGEEASGYEIAVIVRNIDDKSFNQSTWEGVKDYAEHYGISYKYYRVPDKNVQETLNAIDIAVRMGAKLIITPGHIFETAIYKAQDMYTNTHFILIDGEPQDGSYNDYKTAKNTIAILYAEEEAGFLAGYSIVKEGYTNLGVLGGMALPPVIRFGYGFVQGAEFAADELKMPKGSINIKYTYVGNYDNSPANQALAASWYKSGTQVIFAPAGGAAYSVINAAENNEGLVVGIDVDQSFESPTVITSSMKLIRESVYNAVAAYYNGNFNGGKTFILDARVKGIGLPMNTSKFKVFKEYDYNIIYNSLVKKKIKVLKDTDAESVEKLPLNFVKIDYIN
>NC_017243.1|WP_041177159.1|323149_324232_-|BMP-family-ABC-transporter-substrate-binding-protein
MIKKIMLCVLFIISLFVLSCGQQADKDTNTSEIAVLIDLGPIDDKSFNQGSWEGVKDYAENYGITYKYYRVPDKDIDSYLNTIDLAVRCGAKLIVTPGYMFEPAIYKAQDMYTNVHFILIDGEPQDGTYTDYKTSSNTVAILYSEEEAGFLAGYSIVKEGYTNLGFMGGVAHPAVVRFGYGFVQGADYAAVELKLPKDSVNIKYTYVGNYDPTPENQTLATSWYRNGVQVIFAAAGAAGNSVMSAAENNNGLVIGVDVDQSFESPTVITSAIKLIRESVYNAVASYYNGNFSGGKTTVLGAQVKGIGLPMNTSKFKVFTQDDYNIIYDSLVTKNIKVLKDTDAESVEKLPLNLVKIDYIK
>NC_017243.1|WP_014486787.1|324278_325064_-|nucleoside-phosphorylase
MFPKAYYQENENLVHHLKLKKGDVGRYVIMPGDPKRCVKIAKRFDNAKLIADYREYATYTGYINGVKVSTTSHGIGGPSTAIALEELIKVGADTFIRVGTCGGMNIDVLPGDVVIVNGAIKGGGTMDNYIPKEFPCVPNIDVLEAMIEGADKIKTRTHVGVVQCKDAFYAQHAPESMAVDKELLYKWDSYIKAGCLASEMESATLFAVGAAKNVRTGAAMLVLHNQERIKNNINDPKDYTGEEAIDLIIESIKILIEKDKK
>NC_017243.1|WP_014486788.1|325082_325901_-|nucleoside-phosphorylase
MEYNEPKAFYDEEAFKNNLLQYHIKLKKGDVARYVLLPGDPKRVGYIAKFLDNPELKADYREYVTVTGKYKGVDVSVTSTGIGGPSASIAMEELIKVGADTFIRVGTAGGLSLKVKPNDLAIAQAAIKDEGTTKEYIPLEYPAIANTDVMLALRDAAKKINANYHIGVVHSKDCFYGELEPQNSFFREKFENNLKYYTLCGAIASEMECAALFACASLRKVRAGGIMHIVENTMIERMGTHLEYSDNIENMILTALEAIILLNEKDKKAEKK
>NC_017243.1|WP_014486789.1|325955_326606_-|deoxyribose-phosphate-aldolase
MNNLNKLIDHTILRPDATIDDIRKLCIEAKEYGFYSVCVNSAYVNVAYNFLLHSDVKVCSVVGFPLGAMMKEAKAYETKVAVDSGADEIDMVVNVGFLKSKKIDLFERDIKKVRDACHASVLKVIIETCLLTDEEKVLACKIAKECGADFVKTSTGFSTGGATEHDVKLMREAVGKEMGVKASGGIKTYEDALKMIEAGANRLGTSSGIAIVKSSM
>NC_017243.1|WP_014486790.1|326798_327917_-|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MKYMNLYRGYEKRKEAIDKKISSIIERSQFVFGAELDELEKELSNYTGAKYAVGVSSGHVGLVLSLLALGFNAGEDHSQKEVIVPAMTFFSTAEAPAFLGMKVRVCDIDEYFNMDVKKLESLINKNTAAIIPVNLFGQCANYDVILDIAKKNNIFVIEDACQSFGASYKNIKSCSGKLGDIAVTSFFPAKPLGCFGDGGMVFTNNEELYKNLKQLRHHGDEGGMIHVKLGTTGRLDNLQAGILLEKFKGFDADMDHRRSAAEYYNEKLKDVVKVPQVAEYTQSVHAQYVIQVEDNRDEVRAKLNELGVPTALYYPHPIHLAPVLVKKLGYKEGDMPVSEYASKHNIALPIDNDILREEQDMVIEAVKKVVNK
>NC_017243.1|WP_014486791.1|328078_328510_+|ATP-binding-protein
MSIEYCGNKVEKRLSLKIPSDRLLVPKVSNDFLDFLHSNGVKECDAFQIAFEEALTNAIIHGNNNDYNKNVSMYFYIDDEMIKVIIEDEGDGFDYFSAMICLTESQDNIYKDSGRGIFLISLYTDDFYFENNGRRIVIIKNRS

Crispr_ID: NC_017243_4

• CRISPR_ID: NC_017243_4
• CRISPR_location: 415512-415614
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_4

Consensus_repeat	Method
AGCGAGTTTATTTATAAGCAATAAA	CRISPRCasFinder

spacers of NC_017243_4

>4.1|415537|53|NC_017243|CRISPRCasFinder
AAACTATAAACGAGCAGCTGATAACTGACGAAGGAAGTTGTCAGCTAATGTAT

CRISPR arrays and Neighbor proteins around NC_017243_4

CRISPR arrays

The CRISPR arrays of NC_017243_4

>merge|NC_017243|4|415512-415614|CRISPRCasFinder
AGCGAGTTTATTTATAAGCAATAAAAAACTATAAACGAGCAGCTGATAACTGACGAAGGAAGTTGTCAGCTAATGTATAGCGAGTTTATTTATAAACAATAAA

>NC_017243|4|4|415512-415614|CRISPRCasFinder
AGCGAGTTTATTTATAAGCAATAAA	AAACTATAAACGAGCAGCTGATAACTGACGAAGGAAGTTGTCAGCTAATGTAT
AGCGAGTTTATTTATAAACAATAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014486858.1|400493_403097_-|alanine--tRNA-ligase	unknown	unknown	gnl|CDD|234701
NC_017243.1|WP_014486862.1|408061_408841_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187604
NC_017243.1|WP_014486872.1|418686_419136_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486869.1|415626_417180_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223651
NC_017243.1|WP_083818241.1|424092_425217_+|cell-surface-protein	unknown	unknown	gnl|CDD|368488
NC_017243.1|WP_014486874.1|420951_422079_+|CdaR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|226355
NC_017243.1|WP_014486865.1|410715_412191_+|leucyl-aminopeptidase	unknown	unknown	gnl|CDD|234863
NC_017243.1|WP_020064978.1|423836_423932_+|MetS-family-NSS-transporter-small-subunit	unknown	unknown	unknown
NC_017243.1|WP_041177170.1|417954_418557_-|imidazoleglycerol-phosphate-dehydratase-HisB	unknown	unknown	gnl|CDD|153419
NC_017243.1|WP_014486864.1|410049_410547_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486870.1|417181_417814_-|imidazole-glycerol-phosphate-synthase-subunit-HisH	unknown	unknown	gnl|CDD|237288
NC_017243.1|WP_041177169.1|403313_404825_-|DegQ-family-serine-endoprotease	unknown	unknown	gnl|CDD|273938
NC_017243.1|WP_014486867.1|412855_414019_+|NADH-dehydrogenase	unknown	unknown	gnl|CDD|224806
NC_017243.1|WP_014486863.1|409335_409836_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486866.1|412589_412859_+|NADH:ubiquinone-oxidoreductase	unknown	unknown	gnl|CDD|376507
NC_017243.1|WP_014486861.1|406036_408040_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014486877.1|425310_426018_-|zinc-metallopeptidase	unknown	unknown	gnl|CDD|377289
NC_017243.1|WP_014486868.1|414049_415447_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl|CDD|223965
NC_017243.1|WP_014486875.1|422311_423811_+|sodium-dependent-transporter	unknown	unknown	gnl|CDD|271366
NC_017243.1|WP_014486873.1|419441_420572_-|glycerate-kinase	unknown	unknown	gnl|CDD|376844

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014486858.1|400493_403097_-|alanine--tRNA-ligase	gnl|CDD|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NC_017243.1|WP_014486862.1|408061_408841_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187604	cd05346, SDR_c5, classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.1455e-110
NC_017243.1|WP_014486875.1|422311_423811_+|sodium-dependent-transporter	gnl|CDD|271366	cd10334, SLC6sbd_u1, uncharacterized bacterial and archaeal solute carrier 6 subfamily; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter.	0
NC_017243.1|WP_014486869.1|415626_417180_+|FAD-dependent-oxidoreductase	gnl|CDD|223651	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	2.9348e-62
NC_017243.1|WP_083818241.1|424092_425217_+|cell-surface-protein	gnl|CDD|368488	pfam05540, Serpulina_VSP, Serpulina hyodysenteriae variable surface protein. This family consists of several variable surface proteins from Serpulina hyodysenteriae.	2.44092e-153
NC_017243.1|WP_014486874.1|420951_422079_+|CdaR-family-transcriptional-regulator	gnl|CDD|226355	COG3835, CdaR, Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms].	1.47509e-46
NC_017243.1|WP_014486873.1|419441_420572_-|glycerate-kinase	gnl|CDD|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	0
NC_017243.1|WP_014486865.1|410715_412191_+|leucyl-aminopeptidase	gnl|CDD|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	3.62825e-171
NC_017243.1|WP_014486870.1|417181_417814_-|imidazole-glycerol-phosphate-synthase-subunit-HisH	gnl|CDD|237288	PRK13141, hisH, imidazole glycerol phosphate synthase subunit HisH; Provisional.	9.90824e-113
NC_017243.1|WP_041177169.1|403313_404825_-|DegQ-family-serine-endoprotease	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.85021e-167
NC_017243.1|WP_014486867.1|412855_414019_+|NADH-dehydrogenase	gnl|CDD|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	2.71378e-35
NC_017243.1|WP_014486866.1|412589_412859_+|NADH:ubiquinone-oxidoreductase	gnl|CDD|376507	pfam01257, 2Fe-2S_thioredx, Thioredoxin-like [2Fe-2S] ferredoxin.	8.08659e-10
NC_017243.1|WP_041177170.1|417954_418557_-|imidazoleglycerol-phosphate-dehydratase-HisB	gnl|CDD|153419	cd07914, IGPD, Imidazoleglycerol-phosphate dehydratase. Imidazoleglycerol-phosphate dehydratase (IGPD; EC 4.2.1.19) catalyzes the dehydration of imidazole glycerol phosphate to imidazole acetol phosphate, the sixth step of histidine biosynthesis in plants and microorganisms where the histidine is synthesized de novo. There is an internal repeat in the protein domain that is related by pseudo-dyad symmetry, perhaps as a result of an ancient gene duplication. The apo-form of IGPD exists as a catalytically inactive trimer which, in the presence of specific divalent metal cations such as manganese (Mn2+), cobalt (Co2+), cadmium (Cd2+), nickel (Ni2+), iron (Fe2+) and zinc (Zn2+), assembles to form a biologically active high molecular weight metalloenzyme; a 24-mer with 4-3-2 symmetry. Each 24-mer has 24 active sites, and contains around 1.5 metal ions per monomer, each monomer contributing residues to three separate active sites. IGPD enzymes are monofunctional in fungi, plants, archaea and some eubacteria while they are encoded as bifunctional enzymes in other eubacteria, such that the enzyme is fused to histidinol-phosphate phosphatase, the penultimate enzyme of the histidine biosynthesis pathway. The histidine biosynthesis pathway is a potential target for development of herbicides, and IGPD is a target for the triazole phosphonate herbicides.	3.60219e-119
NC_017243.1|WP_014486877.1|425310_426018_-|zinc-metallopeptidase	gnl|CDD|377289	pfam04298, Zn_peptidase_2, Putative neutral zinc metallopeptidase. Zinc metallopeptidase zinc binding regions have been predicted in some family members by a pattern match (Prosite:PS00142), of the characteristic HEXXH motif.	9.40795e-116
NC_017243.1|WP_014486868.1|414049_415447_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl|CDD|223965	COG1034, NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion].	1.38643e-18

Protein sequences

>NC_017243.1|WP_014486868.1|414049_415447_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MIVKFNVDGKTVSSQKGYTILQALSYINIDIPHLCSYKINSTNTFEEKNNILRCKLCLVKVKKKNENDYSYKYACNEIVENGMSVLNEHDDDIIRYRTSLLKAMLYMHEPICESCKADYICRLKKYLDIYNISIEASPNAFDENDINLIELKNILEKMNLPNFINANFERCINCGICEDYKVIDGYNSMITDLCPTHVFEVQRDIDNKINDDISTVRSIESFCIGCNHLCDAKYSYIDYSIKDISSPNGKKYGICDYGRKLDYYSNNTLEKPFYSGMQYEFDEAKELYHKFINDIEAESTLALNSSMYPIEDIKAFNEFIDSLGIQNLIFKKNRMATNSKNIRDNYTNINDFSIRDLKQDIKHSIFDDNYIYNEKFKKFIIVGDSLDDSDNMIDFAKKNKGNYIVFSPNFSVLAYNAYLSFPISYLGEFEGHYIDNHGKVKEMQSFLKVSKNRMSLRELLKYLYL
>NC_017243.1|WP_014486867.1|412855_414019_+|NADH-dehydrogenase
MKKFVLHSENNIENIQSYRDHFGEYLAVQKIGNSFFEDLKEYPLFKRDITQTSIYQLLTDGNIKEDYILVNAASFDYLVFKDKFLLKNNPHLILDGSVFIAKILNIKRIDIILKDYYLEERDILLKAIVEAEDANFVADIEINIYDEYGYYNKYNIRITPSFLENKKYIFDLETISQIAYLAHIGGFTFKDYGNGEYKGSNILSITGDIINPNLYEFEMYTPLRNIVKAAGGTVKEYTIKCVFTNGFLNPPIDFETFQKMTLDYECFDSLNMKMGNGGICFIQEDRCIIRVVVKIIQFGKSISCGKCSPCHYGFDLCEYYINRMLLGNSNFDDYSNLKEAVEMIKIGASCLYIRSLANCILSAMEMFRDEFVYLIENKITLYSFLKS
>NC_017243.1|WP_014486866.1|412589_412859_+|NADH:ubiquinone-oxidoreductase
MASNVKTVIEVCVGLHCSMKGAYGLLEAIRSHYDLEIGVPSSDGMLLKEMECMHNCHNAVPVLINGMECTKSSFKSIIKYIEAIHVRKR
>NC_017243.1|WP_014486865.1|410715_412191_+|leucyl-aminopeptidase
MKLKHTINFIKKHTVAVFVKVEKEQLKVCSFNEEYIKLFNSLVKDKYYNTSTPFAFAFASNTRVIYITYKEVKNYMYETWKNAGASLVKIMKDLHIDDIEVDMAELFAEIASEESYIQFCLGILLSSYSFDNYLGNKRLKEQSNIKNILLVSEHKKDTENAISKANQIASSIFWARDMVNEPSNVINSLTFVDRAKKQAESRKITTTVLTEKELKTLGMNGILGVNAGSKNPPRVFIAQYKKAKAKKHILLVGKGITFDTGGMVLKPSTSMLGMKDDMAGAAAVCGALFLISDMNLEANVTVICPLTDNKTGSAAINPGDILKMYNGVTVEVVNTDAEGRLILADALAYGIKKYNPDFVIDIATLTGACSIALGRHASGLLSNDEALSAALKEAGNDTYERVWELPMFDEYKEDIRSDIADIKNSGGRYAGVITAAQFLSYFTEGARWAHLDIAGTDMSDVNVKYISKGATGVGVYLLAKTVEKLVDIDKF
>NC_017243.1|WP_014486864.1|410049_410547_-|hypothetical-protein
MIRKIFNVAISISLLLFAVSCGTGVSRSQPEGWINDDTFRVMGMGSPSDDIDDKFRREVVAKQAAELDAKNKIAAKIVGSYIESLSSTEKGMIDEYVIQERVAGRIRGTSVIESKWDSKQNCTIVMELYSKNLKKQMDNLVTQYLNEVGMQYTAQDVAGMVRTYK
>NC_017243.1|WP_014486863.1|409335_409836_-|hypothetical-protein
MNKFIKLFIMTSMVSLFVISCGSGVSRERPEGWINDDTFRVMGMGSPAEDIDIDDKFRRELTSKQAAELDAKNKIVARIVGSYIESLSSTEKGMIDEYVIQERVAGRIRGASVVETKWDSKQNCTVVMELYSKGLKKQVDALITKYLNEVGMQYTAQDVAGMVETY
>NC_017243.1|WP_014486862.1|408061_408841_-|SDR-family-NAD(P)-dependent-oxidoreductase
MYVENIKGRTAFVSGASAGIGEAVAKMLASNGVNLILAARRIEKLETLKNELEKNHNVKVTVIKLDFSKPEDIVKAIDSLSDEDKKIDILINNAGLALGKDFYYNNPIEDSLQMIRVNCEGLIVLTRLLLPYILKSKYGHIVNLSSTAADEAYSGGAIYCATKSFVEMFGDSLRIELIDKPVKITNIKPGAVNTEFSTVRFKGDKEKADNVYKGFNPLYAEDIADNIEYALTRKSHVQISSMTIMAENQGSATIIHKNN
>NC_017243.1|WP_014486861.1|406036_408040_-|hypothetical-protein
MGDIDNTRDRLKLDELNKDARKDLFNKFVDAGGEVVPDKKKDNNVLVGSSKKGQNAVVGGNGGRGSKGSSSANTKNDSKNNKSSSAVSVQNKKNTGLFFNIKLWFNALSSGVITLMGGNVNPKFLNFIDKNVIAALLEMDTLIFNALNPSEASDIDAKAKHQKVISQFAKTLDDLELLERIKDQYNEGVYKDFLRPYKELNSTVMAESYVKEIKAMFRPLYVLHAYSSRIKLAGEKAMFAYAMVDNISKGIVNSRISAFKRAVDLIYGKYYPKLFTLLQYASKEPLETINDFNRYLNITDEDILGYYTKIRKEKEKLQETKIQQAKENIGKQKDNEEEKLSKVESIGVKLIDKCVSFKKSDNNIEYEADPFFIVPIKDKIYRIKVLIDFLDREYSAVFVSNKVRYNLVYDNQVRTDYKNDFNNIFLSLSDTNSRLNEYSELCKTINKVEEDKTMRFEQRVSMLSDKNGQRSYLAKNLRNTYVSIITPFKRKLDKLLLDKEERERIIENPNDILTFSAEIGKGKKRIQGYNVMKALTEAYYFISGLNYLITQGELSGAGILIEGDDNEEQDISIAQKQETIENTEASNNTLENVNAENNTGTENENTENNVENDENQISETEESNAENSDNNITDPNEIVLGDDGFNESLEDEDLFTESESEDENLKQ
>NC_017243.1|WP_041177169.1|403313_404825_-|DegQ-family-serine-endoprotease
MEQKKRSFMFFLNLGLTFTLVGIIISFFIFSYEKNYKKDEFLVHAQAAPEKTAFTGSLDGALAVENAIRDVVDKNMPAVVNISTEIEAGQTEEDRYADEFFRFFFGDQMPRQKRSQKSLGSGFIINEEGYVLSNYHVVKGATKIMITLYGEDGELPAQLIGYDEAYDLALLKIEANNRTFPYVALGDSDAIEPGEFAIAIGNPYGLNNTVTFGIVSAKGRSDVGANKYQRYIQTDVAINPGNSGGPLFNIHGQVIGINTLIYSTSGGSIGIGFATPINLATSVMTDLKENGRVTRGYLGIYLQDIDENLSRGLNVKQNSGVYVSEVIPDSPAAKGGLQDGDIIIEYDGEKMTKSGDLFNKVATTKVGKEVNVKYLRNGRERSTKITIEARVEDEEVVPTRQSQNNSQGSTRSWMGLDVSNITPEISQRLQIRSNERGVVVLNMTQNSKAYQYGLRPGDVIKAINGITISNTDDYDNFVKSYGNDKSFTITIKRARMTYVIIIE
>NC_017243.1|WP_014486858.1|400493_403097_-|alanine--tRNA-ligase
MTHLELREKFKEFFKSKKHAIEKSSSLIPIDDPSLLFTTAGMLQFKPYYAGIKKAPYSRVATIQKCFRLSDLENIGKTARHHTFFEMFGNFCFMGDYFKKEAIEFAWEFSTQVIKLPIERIYVSIYEKDDDAFKIWNEHIGVPKEKIVRLGKKDNFWGPAGDSGACGPCSELYIDMGEEKGCGKPDCFVGCDCERYLEFWNLVFNEFFQDTEGNLSPLPNVGIDTGMGLERLCYITQGVESNYQTDVMKPIVDAIAKKLNVKYDDKNKTKINLIADHLRALVFVISEGCTPSNEGRGYVLRRLLRRALKTASDLGHKGSFLNEITSSVVNVYKEIYDYLPKEEENVKRILKDEENKFINTISAGMNKLYAVMEENKESKVISGKDAFMLFDTYGLPIDITEEEAADHGFTVDKAGFEEAMEEQKKRSRGAGEDKRSKFGYVENYETKYVGEETDNLINGVNAKIVAVYEDNAKKDKTSSSNAVIITDVSPFYGEMGGQIGDNGYIENSKKEMIKIIDTQKKENTIIHIADCSSNSLSVGEEIKLFVNFDRRCAIRKNHTATHILQKVLELTLGSHVNQAGSFVNDEYLRFDFTHPDSISEDTLISIENQVNEVVFKSMPAVIKYMPKEEAIACGAKALFGEKYPDTVRILDIGNGFSVELCGGSHLTNTSEVGYFHIVSEGSVASGVRRIEAITGLKAANEASKLFSKVKNLAHILNASKTDELTVRAESLQNEVKKLQKEIKQLKTSGASAVSFMDNFEDLKGIKFYNLEFNEDIKEVRLYADTIKERVKDSIAVMISKTDSSNSILVQITGNALKEKKLSANNIIKDIIAAAGGRGGGKDTFAQGSIENIEKAKEEINKLKSKWL
>NC_017243.1|WP_014486869.1|415626_417180_+|FAD-dependent-oxidoreductase
MPKTRAEILHNSNKKYDIIIIGGGVMGATIALKASRVGLSVLLLDKHDFAFGSSSRTSKMLSGGFNDMNSKNLMYTIHRVRERNNLMYKASSEHFGIINPIYEHSSTGLLREEIKMMLYDMFSLFGKGKKHKSHSRNETLDALPDLINNDVIASVEYYEGLLDDSRYVIELLLKAEEFGADILNYCEVKAFEYNQKEIENVVFTDHISGRVYTASAKTILIAAGAWGHSISSLLPNGNFEDRLVYVKGSHLIIDSDLIHINKSVILPKIKSRPNVFLMRWKNNTIIGPTIKKNTHDLDCIYTTSDEAEYLLDIYNTYFSSIVNKNHIITTQSGMMPLNPSQVKIHSHPQYRLFLVEGGNFTTSSAVTMKTLVKMYGKPYKWFSNQKVVNNKFDKNAELVLNEDLVKFLIDYFGSVNLILKLNELCKNDSSLLVEVGLDYRINRGLIKYFVEVEHAMHLDDIMMRRLRFILTENDCGTLISEHIAEEMANILKWDKSRTEWEIKRYRTEIKRARVALF
>NC_017243.1|WP_014486870.1|417181_417814_-|imidazole-glycerol-phosphate-synthase-subunit-HisH
MTAIIDYEVGNLFSLMSSLKYVGIDAKLTDDEKTIKEADALILPGVGAFRDALAKLERRKDGTLKNTIIEEAKKGKLILGICLGMQMLFDKSYEYGEYNGLGLIKGNICPIEKDLKNKDLKVPHMGWNNLNIKKEDKLFKYINNMEYVYFVHSYYGKDCDESIIADSEYDVQIPAIVKNENVYGIQFHPEKSGNTGLNILRGFKDLVQKS
>NC_017243.1|WP_041177170.1|417954_418557_-|imidazoleglycerol-phosphate-dehydratase-HisB
MRVSEIERNTNETKIKIKLNIDGTGKYKNNTKVGFLDHMLDLFARHGRFDLETICDGDIHIDYHHSVEDVGIVLGKCFAEALGDLKGIKRYGNFSMPMCEALTMTAVDICGRSHLVFNSDLKHEKVGDFDTELVKEFFTAFTNSMNITLHINTLYGENTHHIIESIFKGVARALAQACEIDEKYKNEVLSTKGMLENNKN
>NC_017243.1|WP_014486872.1|418686_419136_+|hypothetical-protein
MIDSESLNSFNDYKHRITKEDVRDKIYKDSNIEKKIKEGVENYLDLSILKKYSDNAYSEYDYLNNYMLITTEVFEEGYIICDIHIDVNMKIYDYMSKGDNKNERYIALDNTYLMGLNLKFSLKEIDDDIENIELRFFNIYGISDNLHQS
>NC_017243.1|WP_014486873.1|419441_420572_-|glycerate-kinase
MKKIIIIPDSFKGSASSLEVCNYIEKGVLKVIKDADIIKIPVADGGEGTVESILYAAGGNIKKINVKNPEGKIIEAKYGIINKDKAVIEMAEASGLTLVDDKTRNPLKYSTYGTGEFIKDALNNNIKEILIGIGGSATNDCGIGMANALGYKFLDKDNNELEAIAENMIKVADIDDSNVDKRIFDIKITAACDVKNPLYGKNGATAVYGKQKGVTEESFDILDDGLKNIAKIIKEKFGKEIDYMEGAGAAGGLGGGLVAFCNAKLKRGIDAVLDIIDFESKIKDASLIITGEGAIDGQTKEGKVPVGVAKRAGNIPVIAIVGQIKEGAEIVYDLGIKSIMPLCTKAMTIEESISNTALLVENASERALRFINIDLK
>NC_017243.1|WP_014486874.1|420951_422079_+|CdaR-family-transcriptional-regulator
MYIDNEMAQRLLDKIMKVIDYEVNINIMNEYGEIIASGDKGRIGKINLGALEVLKNSENMNYFNFIDNEKESSRPGINMPLIFNNELIGVVGVTGDPKEIKLIANMIKMTTEILIEREIDIDKKTLKQTTLNNYIYKIISKENHKYLSSINIWAENNGYSFNINRMVCLIKIEKNNDYDIKKISECILNKIKLIKYFSNQDIISHIGNGQFIIIKSLNDNDKNKTVSLFFKYLRKEIKIQFSVMCGCIVNSLDNIPNSFEQANFLFNYIEYTNNDIYFIEDYILEYIVLNEGYFSSSMILKNTLNIINKNSTFKETIITICKYDLNINKTCEKLSLHRNTILHRMKKIKEILGLDPIKNHTDRIKFYIIAALLEK
>NC_017243.1|WP_014486875.1|422311_423811_+|sodium-dependent-transporter
MSHHHHRGQWGTRAGFILAAIGSAVGLGNIWRFPYMVASNGGGAFMIVFLLAMLTAGIPIMILEFSIGHKTHKSAPGALKALNPSWEWLGWLQVFTCFAIVIYYSVIIAWSLSYGLFSIQGLKWGTDTAGFFTKEYLKLQDGFSLSNFNIGVAIPLVIVWIIILVSVIGGVKDGIEKANKIFMPLLAILVVIILIRGVTLPGALAGLDYMFKPDFSKLTNPKIWIDAYGQVFYSMSVAFGIMITYSSYLPDDSDIANNAFMTGFADTSFSLFAGITVFSIIGYMAHTQGKPVSEVAGSGGIGLAFMVFPEAINSLPGLNGLFGVVFFLVLSFAGLTSAISLAEVVISSFIDKFHFNRKKVSIVIIIIQGAISMVYATGSGLSILDIVDAFINNYNIVVSGLIEIILVAWVYKLGSFKETINTVSEFRVGNWWDFCLKFLTPVFLAVMLSLKLINDFKTPYGGYPTWALFALGWSMPVIAFIAGILLAKFKDRQPNIPHQ
>NC_017243.1|WP_020064978.1|423836_423932_+|MetS-family-NSS-transporter-small-subunit
MGLDSAIFMGFSLLAIWGGFAFFLGIALRKM
>NC_017243.1|WP_083818241.1|424092_425217_+|cell-surface-protein
MKKIFIMMMASLSMSYSSIFGMYGDQDDWIDFLTDGNQFRARMDQLGFVLGNSTIKGTFGFRTQSSLTQLGYILLNNKVGTYLGATISGGIGYTSEAFSIGLGYNYTTASFLPTSDNFGSHTPVLMINALNDNLRIVIPVQILVHNGSIDQLGSYRDNYLGISTDTQIRYYTGIDAFNEIRLYVKYGQLGYKFNTQEVLARSFGFETRFYFLNTAVGNVTINPFIKVAYNTALHGFSTMVRALDGMYEEIGGYSNTTVSPQANINAKWDKNPYDVTVQAVLGVTANSDIVSLYVEPSLGYKARYLGKMQYEKVNYDFKVNHYLSWGAYAELYITPVKDLEWYFEMDVNNSDSYSTGTPVSFASTTGITWYLPEF
>NC_017243.1|WP_014486877.1|425310_426018_-|zinc-metallopeptidase
MFGYFEYYFGYIWILIPGIILGFWAQMKVKSTYAKYSRMENKRGITGAQTAKYILEGYGIDIPVERIGGTLTDHYDPSSRVLRLSHGVYDGTDVAALGVAAHEVGHAIQHNRGYAPLSIRNGFYPLCAIGDQFGPFLVLLGIMIGGAGSFSYYIMMAGIILFAFAVFFSLVTLPVEFDASNRAIKILDKGGFLDSEELDGAKKVLSAAALTYVAAAVTAILTLLRLLMLAQRRRD

Crispr_ID: NC_017243_5

• CRISPR_ID: NC_017243_5
• CRISPR_location: 610938-611043
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_5

Consensus_repeat	Method
GAGTAATGTTGGAGGCGATCAAATTG	CRISPRCasFinder

spacers of NC_017243_5

>5.1|610964|54|NC_017243|CRISPRCasFinder
GTGGGAATAAAAAAGAGGTTAAATAATTATGTCAGATAAAATAAATCAATCTAA

CRISPR arrays and Neighbor proteins around NC_017243_5

CRISPR arrays

The CRISPR arrays of NC_017243_5

>merge|NC_017243|5|610938-611043|CRISPRCasFinder
GAGTAATGTTGGAGGCGATCAAATTGGTGGGAATAAAAAAGAGGTTAAATAATTATGTCAGATAAAATAAATCAATCTAAGAGTAATGTCGGAGGCGATCAAATTG

>NC_017243|5|5|610938-611043|CRISPRCasFinder
GAGTAATGTTGGAGGCGATCAAATTG	GTGGGAATAAAAAAGAGGTTAAATAATTATGTCAGATAAAATAAATCAATCTAA
GAGTAATGTCGGAGGCGATCAAATTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_041177196.1|595892_596147_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_020004042.1|620813_621017_-|50S-ribosomal-protein-L31	unknown	unknown	gnl|CDD|234576
NC_017243.1|WP_014487024.1|619960_620665_-|hypothetical-protein	unknown	unknown	gnl|CDD|225917
NC_017243.1|WP_014487015.1|601327_603664_+|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl|CDD|308794
NC_017243.1|WP_014487020.1|613637_613880_-|DUF2442-domain-containing-protein	unknown	unknown	gnl|CDD|378424
NC_017243.1|WP_008722843.1|613882_614137_-|DUF4160-domain-containing-protein	unknown	unknown	gnl|CDD|379344
NC_017243.1|WP_014487023.1|615893_619019_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_017243.1|WP_041177195.1|594242_594707_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487011.1|594858_595860_+|restriction-endonuclease	unknown	unknown	gnl|CDD|377369
NC_017243.1|WP_014487012.1|596689_598051_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240543
NC_017243.1|WP_041177200.1|615164_615416_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487014.1|599813_600242_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177199.1|612237_613044_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177198.1|611260_612241_+|hypothetical-protein	unknown	unknown	gnl|CDD|372307
NC_017243.1|WP_014487016.1|604460_607232_+|isoleucine--tRNA-ligase	unknown	unknown	gnl|CDD|235588
NC_017243.1|WP_014487021.1|614414_615032_-|HD-domain-containing-protein	unknown	unknown	gnl|CDD|370050
NC_017243.1|WP_041177197.1|610372_610648_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_148258803.1|621245_623039_-|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|214599
NC_017243.1|WP_014487017.1|607485_610302_+|N-6-DNA-methylase	unknown	unknown	gnl|CDD|378996
NC_017243.1|WP_014487013.1|598232_599663_+|sodium:solute-symporter-family-protein	unknown	unknown	gnl|CDD|271357

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_020004042.1|620813_621017_-|50S-ribosomal-protein-L31	gnl|CDD|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	1.2742e-34
NC_017243.1|WP_014487012.1|596689_598051_+|MATE-family-efflux-transporter	gnl|CDD|240543	cd13138, MATE_yoeA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	8.56112e-119
NC_017243.1|WP_014487020.1|613637_613880_-|DUF2442-domain-containing-protein	gnl|CDD|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	2.28285e-07
NC_017243.1|WP_008722843.1|613882_614137_-|DUF4160-domain-containing-protein	gnl|CDD|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	7.13252e-22
NC_017243.1|WP_014487015.1|601327_603664_+|BspA-family-leucine-rich-repeat-surface-protein	gnl|CDD|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.88568e-50
NC_017243.1|WP_014487023.1|615893_619019_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_017243.1|WP_014487011.1|594858_595860_+|restriction-endonuclease	gnl|CDD|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	1.97786e-06
NC_017243.1|WP_041177198.1|611260_612241_+|hypothetical-protein	gnl|CDD|372307	pfam12775, AAA_7, P-loop containing dynein motor region D3. the 380 kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases. The core of the 380 kDa motor unit contains a concatenated chain of six AAA modules, of which four correspond to the ATP binding sites with P-loop signatures described previously, and two are modules in which the P loop has been lost in evolution. This particular family is the D3 and is an ATP binding site.	0.00413543
NC_017243.1|WP_014487016.1|604460_607232_+|isoleucine--tRNA-ligase	gnl|CDD|235588	PRK05743, ileS, isoleucyl-tRNA synthetase; Reviewed.	0
NC_017243.1|WP_014487021.1|614414_615032_-|HD-domain-containing-protein	gnl|CDD|370050	pfam08668, HDOD, HDOD domain.	6.30849e-05
NC_017243.1|WP_014487024.1|619960_620665_-|hypothetical-protein	gnl|CDD|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	1.16686e-39
NC_017243.1|WP_148258803.1|621245_623039_-|methyl-accepting-chemotaxis-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	2.88911e-55
NC_017243.1|WP_014487017.1|607485_610302_+|N-6-DNA-methylase	gnl|CDD|378996	pfam12950, TaqI_C, TaqI-like C-terminal specificity domain. This domain is found at the C-terminus of the TaqI protein and is involved in DNA-binding and substrate recognition.	3.29188e-23
NC_017243.1|WP_014487013.1|598232_599663_+|sodium:solute-symporter-family-protein	gnl|CDD|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	1.30511e-97

Protein sequences

>NC_017243.1|WP_041177197.1|610372_610648_+|hypothetical-protein
MITVYNKIGTSNENPPSGYNTWKEYWEDKKEIKFQKCSNLACNNDAEVGAHVYPNYSHDTTYIVPLCKECNYIYNQSPMNVERIDLLRLNQ
>NC_017243.1|WP_014487017.1|607485_610302_+|N-6-DNA-methylase
MAKYNSAKQKSYDIIGHLVDNFKNGTKSKNETETRRYYIDKFFEALDWDVGNEKGKREVIHEDIVKVKGKTKFPDYGFYFKGKRVFFVEAKDTKVDIKNDSKPAFQLRSYAWSAKLGVSILTDFEELAIYDCTVRPKENDRTEAARIKYFTYEDYLKEEVFDYIYDLFERDNVANGSLDAYSENLCNRKGSETVDVHFLNTLDELRTKLAVVISKLNKEMSEKDINYAVQQIIDRIIFLRVAEDRNVENYGLLALANPKNKNEDDFKNYGFNAENSYYCNLNYIFDKANEKYNSGLFNEDDIVKNLNIDDKTIKEIIEELYTPRNPYQFSVIPVEIIGNAYEQFLGKTITIGKNHSAKIELKPEVRKAGGVYYTPEYIVDYIVANTVGEAIKGKKPEEIANIKILDPACGSGSFLLGAYKYLLNYHIEYYNKIKDRAKFKGSKEDVIKENGDLTIWIKKQILRNNIFGVDIDSNAVEVTKLSLLMKCLEGESPASIQNNQDLFNERALPSLEDNIKCGNSLIGNDFYESQSVLYFDEETQYKINCFDWEDEFKNIFKGGGFDVVIGNPPYVRIHLLDKIQLDYFKDRYSVYKGQIDLYSLFIEKSISYLSKSNGVVSFIVPRFLKFNIDSEEVRKLFLKYNIKQLVEVGKAFKNVSTECIVFLVSKDDKKEDIKIYDYYPNKDVTFVKTMDKNMFYNFPNIIFNTIVSEEEINIINKMLSISVKVSEICSLKRGMEIGKKDIRENKSGIPTLLGEEVSKYQIVYENTYCLENHKEVSRLKLFSEVEKILIRRVANQLIATYDNENYYFIKNLYSLISKDYNLKYILGLLNSKLLNFFFKKYFTTKKEDIFPEIQAYHINELPIYKIDLNKKEEKEKYDKIIELVDSMIILNKKLISEKNPNSLNMINRQISACEKQLDNLIFSIYNLNDEERRIIEGD
>NC_017243.1|WP_014487016.1|604460_607232_+|isoleucine--tRNA-ligase
MDYSSTINLPKTAFPMKAGLKEKEPKIIKKWEDEKLYQQLRELRKGAPKCILHDGPPYANGDIHIGTSLNKIIKDIIVRYKSAKGFDSPYVPGWDCHGMPIELKVQESLGDKYKETSKFIMRKKCRAYAQKYIDIQRKEFKRLGVMGDWENPYLTMSPEYESEIVEVFAQLVEKGYIYKGLRTIHWCMDCETALAAAEIEYDDNHTSTSVYVRFPVLNKINDKLDGNVDVMIWTTTPWTLPSNMACAFNRDLEYVAVEIDGRYAIMTTSLVDTVLSKKDMKAEGRDMIPVSMEEIEKLEIAHPFIKDRKSAVVFADYVEATAGTGIVHTAPGHGMEDYQTGMNYGLEIYCPVDKAGRYTSDFPEMQGMKVRDANPKVVEILENNGSLYHKEKVTHSYPICWRCKNPLIFRATSQWFMNMTHDNIDKRTVKALDNIKWYPTWGHDRMQKMLENRPDWCLSRQRSWGVPIPAFYCKNCGKTLLTAESTRHFAEIVKTKGMDVWFELEAKDLLPEGTKCECGSCDFDKEQDILDVWFDSGVSSFAAQKTNKDLDGVFPVDIYLEGGDQYRGWFQAAIWPSMAIRGIPPYKELVTHGWTLDEQGRAMHKSAGNVVSPLEVIDKYGADILRLWCISEDFTHNARVGDNMMKAIADNYRKIRNTFRYLLGNISDFDFTKDKIEVKDLLPVDRYALSRLHSFIKVAEKACDGYEFHLFYQRLINYCVVELSATYFDIIKDRLYCDRKDSVSRRSAQTVLVEILDVLVKIIAPVLPFTTDEVWGYYKGENASSVHLELYPKADDNLIDLELEKEWASILKVRDDVLLSLERARDNSTIGKSLEAYVTICTKEPATKELLTKYEKYLNEIFIVSKVTLSDSKDDTFIEGGVSFVKTEKASHEKCVRCWGHYDSVGTDSEHKELCTRCAEAVR
>NC_017243.1|WP_014487015.1|601327_603664_+|BspA-family-leucine-rich-repeat-surface-protein
MHKYKPEILKELYEIVQDESIYLGDIDTSLIKDMSGLFSGSEREDFSGIEIWDTSNVVSMNSMFSFARKFNHNINNWNVSNVEDMGYMFRYAIKFNQPLNNWNVHKVKIMNYMFNDAMEFNQDISSWNVESVKDMTCMFEGCSKFNQPLNSWNVSNVENMYCMFAQSFEFNQPLNDWDISNVKDTSYMFYLASKFNQPLDKWNVNKVKNMSYMFGGTYNFNKYSSLENWDISQVNSMENIFQFCNNFQNFKNLKWTLYLHVLGDYYYGNDIIKDNLKEAHKIASESKNKKIISFKRKLENTYYNELKDLSDLKIFKSIEEAEDYIENNLNKKDEKKVDFIKEASVLIKDKSREVNIKVIKYIYLKYLELKKYIYRIVEIDSIIELLDKESFLSFAYNIYKETDKETAQLIYGLYGGYEALEEIYKKDGESKLFFNILSLNKENEYTIKILFNIYNNAKKMATKNNALDILIEIAKYKKNPFYNLELKYNSNIGFDKNSEKILDENYKLILNNDYSVSIFDIKESKILKSIPRNLDENKKEEIKHIREQVSNMIKKFSYILNQLLIAGDKYNYDFFKEIFIDNPIMNKFDLSLIWSLYNNSNNFITTFRYAGDGSYTNCNDEEVKIDNNSFISLASPIEMEEETITKWRQQLQDYELSQTINQLSIINIDKNNLENEIDKLQNIEIAYGTFKAFGMRYGMFPLYTEYRTIKEYTLTLDDGDTFTIKAKINGETDYADYKDKIKINIEFTNNENKEVSKRFIYTLLIFMIWDFRLTDMFN
>NC_017243.1|WP_014487014.1|599813_600242_-|hypothetical-protein
MIKKILTIFLTLFLVGILSVSCSNADKTGSGETTKGIEQYNGNNYVSTSTVSANQYLWVLVKDGKIDMVTDTDNNTAPTYGTDIDFSVTGSTSTDYVFSSADGTIAGSLRFAPDGSILVVRFTKNPDASESILNTDITCNKK
>NC_017243.1|WP_014487013.1|598232_599663_+|sodium:solute-symporter-family-protein
MGGTIVIIIVVLYLVAMLLIGVYSSKKISNSNDFALAGRNLGPVLLAGTLAATNIGGGTSLGLAEQAFGKWGLSAVWYVITASIAYLVLAFLAQRFRNAMVTTVSEYFYKRYGKANALVTSIIMGLPMIGITAAQIIASASILTVMTGWNYKLSVVIVTIVVTAYSSMGGLWGVAFTDLIQGSLVFIGSLVAIPFALNYAGGFDHVLANLTPAQKSFTAGMGWPTIISLTIMYIASYSVGPEISQRFFSARDSKSLMIGSLVGGLVCILYSLFPAFLGLIASSVVKDGLLTSELLTSEGTRYILPVLAMHTMPPVIVGLLFSALISATMSSADSDMLAVSVIATNDIYKKYINKDATDKQLLFLGRACMVAVGLISMFIAFKASNLITILMFSFSLRAAGVFIPYLFGNYTNKKLSAVASMGSLIAGSVVTIFFQYNKNINLFGVDPIIPGIVASLVVFLVLSAIIQPKPDSAKTE
>NC_017243.1|WP_014487012.1|596689_598051_+|MATE-family-efflux-transporter
MANHIGTDLTEAKVVPTLLKLLIPILLSNMLNVVYNIVDSIWIGNIIGPLGLSAVAVSFPIMLIMGSFAFGINMANGVIVSQYYGAKDYDTVSHVIKVSTTLGVIILVTVGALMLIFSRNILVMMKTPENAMDMALIYLRISILGMPFAYTYFFISSILRAVGDTVRPLIFLIVSSIINIILDPILIKGFWIIPAMGLQGAAIATVISQFTSVFISTTYLRIKNSFIKINPFVFTFDLNMTKKILKLGIPISFNQFIVAFGWLVITRLISSFGEAASATVAIVNRVESLFIMPMGALGNAVMTMSAQNIGAKKLERVKEILKSGIVIGIIISSIMSIFSITNPYLLIRMFTKDTQVFEYARSYIYTIMPIFIFYSVMFVCNGIINGAGKTIVIMAFTTSTTLILRTILAYALSPNFGLVGIWLSMGICYIINTFFSMYYLKSNKWQKNSNITL
>NC_017243.1|WP_041177196.1|595892_596147_+|hypothetical-protein
MAQNFYCEYCGAKYSSIASLTSGYCLKHPNGPNKGKHKLYEGGEKSEYFCKYCGAKNKSLQSLVNGYCLKHPNGPNKGKHSPAL
>NC_017243.1|WP_014487011.1|594858_595860_+|restriction-endonuclease
MERNYFLHRISHGYECSYPILEKGYLSTGYEMLFSEELYKIVENGDYYGEFKSYVENIWGECPKWIHHLWRFIHGFKKGDYIIVPQFGGLFSIYEIIGDNFIGKNDKELKSVLKPFINTEDYQKLDFFWKVKPVYTNIKRAEYANAELTRKMHYRGTNISCNDIAETINELLENINNNRPINLTYDILNTCSKNIFDLVRNRLNPDKFERLIGLYFKQCGADNIERPSKIDNPNGDCDIQASFDLIRTIIHVQAKFHTDYTDQWAIEQIKNFLEYKSSNEDGYSHIGWVISSCDDFSDEAKNLAIDNNILLINGKTFSEMLIKAGISSLEGNI
>NC_017243.1|WP_041177195.1|594242_594707_+|hypothetical-protein
MGKKFLTIFLSLFFVSMLSISCSNKDKTGSSDGSATTTKGIEQYNGNTYVSSKIQINNQLGYVWISVKDSKVAIKPNEDNNTSPIFDTGNYFSVTGSGTDYNFSIPDSKQNPDSIVGTLTFSDDASYVTLNITKNGDDPTGETLNKHFVCNIKK
>NC_017243.1|WP_041177198.1|611260_612241_+|hypothetical-protein
MDMMEKNPKNILISGDSLSGKSSCIKYLIMNLSNSFTTIFIDGNGDIQLPIKSHIERMKKKCYNRIPDNETTIVFIDNFHQIKNSDKRNKILEFFNKEKNIYLIITTDKLYNLQIIKNSIFDTSYEILPLGYALEDKLINNWLEIVDFTKEDFNQKRIYYSSLINNIFLKYTMPRYPFFFYTILYSLYNNTKGLSVNITSEYYCYYFLISQCLLNANIELNQFDMYLNILSEISYLFFKRITSKNIKDKKLKEEMILDFLENDYKTRYNINENISIDKILSKLHNAKIFVYSDIREYHFAYPYIYYFFLGKYFSENLNDNMEDIKK
>NC_017243.1|WP_041177199.1|612237_613044_+|hypothetical-protein
MIDNLHILENSYIIMFLIYNTKNSDILEYLNSSILSYLKNEKIMTLKNEDVNHLDKYSEKISNIVLSNIDIEKNREDHFKRMDKFEEDYNLNTDMYEEADTYDDNFLEIKKSIKSIELMGCIIRSRHASLLRDNIYRYFTNSVILSLKISNNLFGILQKEEKEFVNWIETKMLEEDIDNINNIKNIVDFIVYQIYYLISIFTIKISSQYLCSENLIYCINELKEEMPLPIIFLIEKDIKLNYKQNVDTSEIRKILSDKNISKYVKKYI
>NC_017243.1|WP_014487020.1|613637_613880_-|DUF2442-domain-containing-protein
MTFHKIKNVKALDNLILEIIFENEEIKYYDIKKLISEHKEFEILNDKTLFNLVKVDVGGYGISWNDDLDISCNTLYYSPS
>NC_017243.1|WP_008722843.1|613882_614137_-|DUF4160-domain-containing-protein
MPVISRFYGIIIKMYFQQKEHNPPHFHAIYGEYVGVIDINELKMIEGDLPNKACSLVLEWAKNNQDELLNIWNTQNFKQLEPLE
>NC_017243.1|WP_014487021.1|614414_615032_-|HD-domain-containing-protein
MEILDLERAEYELNKAYKSNPTPWAEHSRYVAKAARIIASEYNKKSTNKKLDEDNSYIFGLLHDIGRYTGISVERHLIDGYKYCINYGWEKMAQICITHAFMIQDVNTAIGKFDMPEEDFNFIKNFVANAVYDDYDLLIQLCDCLALPSGFCLLEKRFVDAALRYGTFPQSALRWKRVFEIKSYFESTIGTSIYNLLPNIKDNIF
>NC_017243.1|WP_041177200.1|615164_615416_+|hypothetical-protein
MTFIISSILSLFLLSSCSPAFDRMFHTPPYHPHARNYFDFPMLFGPHFGIHGILSIIIKILIIVALVFLVKMLYNKDKNNKKE
>NC_017243.1|WP_014487023.1|615893_619019_+|efflux-RND-transporter-permease-subunit
MKNFITFIVNRPTTVFVTLVSMFIIGFISISRLSINYLPNMEVPIISIKTTYDNAGAEEVEKSVTRIIESAVSSVNNVKTIKSKSKESESNVEIEFNWGTDLQTAADDIREAIDMVRSSLPDDADNPNISKFSTDSEPIMNIAFFGTDNLASLYDLVDSQILTRLEQVEGVAQTEIRGGLKKIICVDIDLNRLNAYSININDIVHTLSLENQNVAGGETYEGVYKYNIRTTGEFKEVNDIEDVVIMLKNQVYPVKVRDIAYVHEDYEDDSEIVRINGQKALTIAVTKESGGNIIQIARDVEKRLSTINLPSGVYYQILFNSSDTIKNSIHNVLNTVWQGALFAVLVLMIYLWDIRSVFIISISIPVSVITTFILMYFFNITINVISLSGLVLGVGMMVDNSIVVLENIFYYSNYYSKYNINKNDKRTIKINNIKSSIIGTNEVSIAITASTLTSVCVFLPFLFVKGQMGQMFSDLCITVSISLLTSLFVALTIVPLLASRLNKLNPDSKLNLLLRKSENFFNKNLHNNVEKFYVSTLAIVIKNKKKSFALISVILTISLFLLLMNIGKEGYPVSDEGTIISRLRLPVGARVEFTDMFINKMEHDIESAVSNNMAYYETRVRTGRNEHHGEVRVKLIDRENGRKLDITHYIESIRNKVNGYPGRIELNSENTAMGKPKNYSAIIIELVGDDLDRGYDVASNVIAAVNNVEGVRNVLIKEDDSNHELIFDVDRDLVSKMGININTIANIIRTSFSGTTASKMTLNNSIYVDTDIIVRLEDRNRDDISSIQKMMIPTSNGIVPISSLVSIHKSTGPIEINRKNDKRIIEINASAYGRPINEIITDIRKELNKIYIPSGFSVNFSGDYEDMQEAFVQLIVSLIMALVFVYAIIAGQFESYITPFVISLAVPFALFGALIFLYFSGNTLNVYSGIGIIMLVGIVVNNGIVLIDYMNRVVIERNISWDNAALESCKRRLRPVLMTSLTTILGLLPMIFEIGSGSEMYRPLAIAVCGGLIFSTMFTLIIIPSVYSSFRNRFNMKIRED
>NC_017243.1|WP_014487024.1|619960_620665_-|hypothetical-protein
MKFIIEDRVFETLNDMCVAVIIAKRINNQNKINDISIMLKESISNAEKEFENIKIKESEYIKCYRDAFQKLNINPNKFMCSIEALLTRISKNKGMPEINSVVDLVNAVSIKYKLPMGAHDLDSMNNEDFYIRYSVDDDTFLPFGETETEKVDNNELVYAVAHDIRTRRWIWRQSEYGKITENSSNIIFPIDAFIGINDDKAIKARDELAELLAKFFNCDIKTGIIDSKNNYMEF
>NC_017243.1|WP_020004042.1|620813_621017_-|50S-ribosomal-protein-L31
MKKDIHPQYFETDVNCACGANFKIHSVQKSLHVDICHNCHPFFTGKQKILDTAGRVDKFKKRYGLKK
>NC_017243.1|WP_148258803.1|621245_623039_-|methyl-accepting-chemotaxis-protein
MIKFILPFAIFLTIMYFIILFVYKNIYINSFFNTKTFKAVSIHDLIESKLNNVNEVIDILDSYLKINDLPYEYFGDAITNIAKLSDDYMNIYFGNTIPYPTGGIFINSLEPFPPDYDQTSRGWYKSAVGNNKNIYITDPYVDFVTKKICITFAKAVYTNNNQLKGVVAIDFAKMDDIVQNTIYEENVNLVTKNGMFINNTDENKILSENNKIFNDINFPNIQQYIIDGKNYTNIYKNNWYMVQKLETVPWSIVLSGNLSQVQNQIKALMFILLFVLIIIILLESVLVVVIVNPITASLDQAIANIKLMNDGYFNSNFNEKMLSKKDQTAELYKNIKSMQDNIGKIVYNLKENINNINSSIDTIQYGSKNLSDRTTSQAASLEELSASTESLSNSLRNTSVNTEHAKNMSLEVANSTLTGVEAVNVISNNMAEISESSKQISDITKLIQSIAFQTNILALNASVEAARAGEQGRGFAVVASEVRSLAQTVNEAANNITKIVNDTVAKIEHGNESVAYSTDVLQKISSSAKEVVNILTEISTTALNEQNSIMQINQTIISLNSITQENSSIAEESASSSNEVKNMTEDIVNDINYFKFS

Crispr_ID: NC_017243_6

• CRISPR_ID: NC_017243_6
• CRISPR_location: 1251935-1252090
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_6

Consensus_repeat	Method
TAATCCCGCTTTCCTGTATATCCAGAAACAGTTTATTAAAACTGCTCTTTAA	CRISPRCasFinder

spacers of NC_017243_6

>6.1|1251987|52|NC_017243|CRISPRCasFinder
GCTATAAGCAACAGGGTATCGAGACTACACAAAGCACCGATGGAATGTCGTA

CRISPR arrays and Neighbor proteins around NC_017243_6

CRISPR arrays

The CRISPR arrays of NC_017243_6

>merge|NC_017243|6|1251935-1252090|CRISPRCasFinder
TAATCCCGCTTTCCTGTATATCCAGAAACAGTTTATTAAAACTGCTCTTTAAGCTATAAGCAACAGGGTATCGAGACTACACAAAGCACCGATGGAATGTCGTATAATCCCGCTTTCCTGTATATCCAGAAACAGTTTATTAAAACTGCTCTTTAA

>NC_017243|6|6|1251935-1252090|CRISPRCasFinder
TAATCCCGCTTTCCTGTATATCCAGAAACAGTTTATTAAAACTGCTCTTTAA	GCTATAAGCAACAGGGTATCGAGACTACACAAAGCACCGATGGAATGTCGTA
TAATCCCGCTTTCCTGTATATCCAGAAACAGTTTATTAAAACTGCTCTTTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014487576.1|1260853_1261363_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177286.1|1259887_1260295_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487570.1|1257289_1258261_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487569.1|1256860_1257229_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487558.1|1236426_1238130_+|flagellar-M-ring-protein-FliF	unknown	unknown	gnl|CDD|235668
NC_017243.1|WP_014487567.1|1253596_1256353_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487560.1|1241683_1242136_+|flagellar-export-protein-FliJ	unknown	unknown	gnl|CDD|131526
NC_017243.1|WP_014487557.1|1235718_1236198_+|CinA-family-protein	unknown	unknown	gnl|CDD|334938
NC_017243.1|WP_041177285.1|1256570_1256837_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487575.1|1260320_1260773_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487564.1|1248228_1251342_+|hypothetical-protein	unknown	unknown	gnl|CDD|372833
NC_017243.1|WP_014487572.1|1258781_1259705_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487571.1|1258284_1258638_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487563.1|1245308_1247300_-|VacB/RNase-II-family-3'-5'-exoribonuclease	unknown	unknown	gnl|CDD|273947
NC_017243.1|WP_008724563.1|1238186_1239218_+|flagellar-motor-switch-protein-FliG	unknown	unknown	gnl|CDD|235561
NC_017243.1|WP_014487559.1|1240197_1241652_+|FliI/YscN-family-ATPase	unknown	unknown	gnl|CDD|224079
NC_017243.1|WP_012670212.1|1239259_1240162_+|flagellar-assembly-protein-FliH	unknown	unknown	gnl|CDD|235850
NC_017243.1|WP_041177284.1|1243059_1245162_+|6-bladed-beta-propeller	unknown	unknown	gnl|CDD|271320
NC_017243.1|WP_014487565.1|1252180_1253062_-|CAP-domain-containing-protein	unknown	unknown	gnl|CDD|131955
NC_017243.1|WP_014487561.1|1242156_1242882_+|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl|CDD|381617

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_012670212.1|1239259_1240162_+|flagellar-assembly-protein-FliH	gnl|CDD|235850	PRK06669, fliH, flagellar assembly protein H; Validated.	3.79275e-77
NC_017243.1|WP_014487557.1|1235718_1236198_+|CinA-family-protein	gnl|CDD|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	1.22063e-78
NC_017243.1|WP_014487558.1|1236426_1238130_+|flagellar-M-ring-protein-FliF	gnl|CDD|235668	PRK06007, fliF, flagellar basal body M-ring protein FliF.	2.03683e-130
NC_017243.1|WP_014487563.1|1245308_1247300_-|VacB/RNase-II-family-3'-5'-exoribonuclease	gnl|CDD|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	3.09433e-174
NC_017243.1|WP_014487559.1|1240197_1241652_+|FliI/YscN-family-ATPase	gnl|CDD|224079	COG1157, FliI, Flagellar biosynthesis/type III secretory pathway ATPase [Cell motility and secretion / Intracellular trafficking and secretion].	0
NC_017243.1|WP_014487564.1|1248228_1251342_+|hypothetical-protein	gnl|CDD|372833	pfam13945, NST1, Salt tolerance down-regulator. NST1 is a family of proteins that seem to be involved, directly or indirectly, in the salt sensitivity of some cellular functions in yeast. It does this without affecting sodium accumulation. It negatively affects salt-tolerance through an interaction with the splicing factor Msl1p. This interaction stresses the importance of efficient RNA processing under salt stress conditions.	0.000875734
NC_017243.1|WP_041177284.1|1243059_1245162_+|6-bladed-beta-propeller	gnl|CDD|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	1.13736e-65
NC_017243.1|WP_014487560.1|1241683_1242136_+|flagellar-export-protein-FliJ	gnl|CDD|131526	TIGR02473, conserved_hypothetical_protein, flagellar export protein FliJ. Members of this family are the FliJ protein found, in nearly every case, in the midst of other flagellar biosynthesis genes in bacgterial genomes. Typically the fliJ gene is found adjacent to the gene for the flagellum-specific ATPase FliI. Sequence scoring in the gray zone between trusted and noise cutoffs include both probable FliJ proteins and components of bacterial type III secretion systems.	1.24503e-07
NC_017243.1|WP_008724563.1|1238186_1239218_+|flagellar-motor-switch-protein-FliG	gnl|CDD|235561	PRK05686, fliG, flagellar motor switch protein G; Validated.	2.25011e-157
NC_017243.1|WP_014487565.1|1252180_1253062_-|CAP-domain-containing-protein	gnl|CDD|131955	TIGR02909, conserved_hypothetical_protein, uncharacterized protein, YkwD family. Members of this protein family represent a subset of those belonging to pfam00188 (SCP-like extracellular protein). Based on currently cuttoffs for this model, all member proteins are found in Bacteria capable of endospore formation. Members include a named but uncharacterized protein, YkwD of Bacillus subtilis. Only the C-terminal region is well-conserved and is included in the seed alignment for this model. Three members of this family have an N-terminal domain homologous to the spore coat assembly protein SafA.	2.50351e-22
NC_017243.1|WP_014487561.1|1242156_1242882_+|lytic-transglycosylase-domain-containing-protein	gnl|CDD|381617	cd16896, LT_Slt70-like, uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.66528e-45

Protein sequences

>NC_017243.1|WP_014487564.1|1248228_1251342_+|hypothetical-protein
MSNNHSKKRYSYTPDSQTYNPFDQLFNSDENTVNSDNNNNRNNNNNRNNNNNRNNNNNRNNNNNRNNNNNRNNNEIYYLSYFLREDKKNNDRDKNKIKKLLIPLLTFIVENKQFKDEKSHLKKDFAVVIRNRFEKLPSEYKDEFIKEDNMLIRQNVLEYKINNAFTEAAVFLRDFRNIMMHKNVKEDTFSRCKFKKFQGDLFTFLILNMKAAFGINDKQKSLLKEKNKEEGIKLSSDKFEIKNEYIKKVLEMNAERMGENFANVPFIYALSILAMFVESKYIKDILDLIKLKKFIEEFILSFSLRGGYKTFVPGISLEDDELYLKQIENEYIVNDEVSTTGRRLKKNLSYFNINDIDVNNDFAVYKKILKFYSYRTSFPKIEEFEDLIREFKAKEIANANKNKIEGIIEFNRNVEEHNAKVEYNKKLIKQPVPSLETDYKNIIPLLTNVFRNEDIFIKEAAEFLSLKYKSQFGNDTWTIAGNTIIWIEPNDDILFDVRRKVKPSKNGLHSIYKIVYSKKNAERYSLNRYNLRALITSILINGGVEFKKLKTTASDNCPPSNNKETNKVNNDRLLIDAIKKKSENWNRYQQASFIIKVIRRSAMKNEELHNRDSVAFFQEFARVLYLLDNRNGNVYDDIIAVMHRYKVNTSNFSDKVKNILKCHTLSEMLNQSFTLFTIPNKEIKNDSDNLLFKTWSKFAFLPYNEKNKEISDILQWNNIKTKYDIKNKNADLFDILSKVFEQEKMTPPHLVDIYNDYIKNNKIDKYRNKEIRNIIAEEMILTYISLQYVNNMNKNRNSYFRLESYEDKTDNSPLKFNLIWELNPIIKIDIKDYMKKDIRSALNWIFDVSRIKEEGKIEGKEDLQKCLTNVIRSYKIITSHDILKNKCPKVSAEIGKDILNADNIKDMVKVLIWAQKELLYFICNMEANIIYTLNKIYTQAEIDELTREDGYFNFGDLVSLHNKNIEQIKYLDNHKNNSALDIRIINVRNMLAHGRLFDKSCELNYKSAISILDDAMKRTLEKSLQDVYLKNNKYNKK
>NC_017243.1|WP_014487563.1|1245308_1247300_-|VacB/RNase-II-family-3'-5'-exoribonuclease
MKVIKLLKRINKEKELDISEYKNKYVETKKDKLRFDKMLQKSVSMGLVMKKSNTLKLTNEGKIYLERELKQITNKERDILKDRKSKSKNKKNDTGNKKTSIPKPEIKIDVNNAKKDAEIIAKAYNVPTEFPKKCLEEAKLLPDSMENVELEFDRIDLRDIRTVTIDGADSKDFDDAISIEKLNDGYKLGIHIADVSHFVVMGSALDREARKRGNSVYLIDTVYPMFPHELSNGICSLNEGVSRFTMTVFVTIDNQGNVKESTFHKSVIKSSRRLTYDYAQDVLDGIEQDEDWLVELLKNADDVKKILLQKRIDNGSIEFNLNETQIILDKGGNPKDFFIGERKETHKIIEELMLIANCEVAKRLKNIKGSIYRVHDSPDQEKLDTFTRIAFNRGYRVTRDADGNLDFHSFIESIMGKPDEKLLLTLLLRSMKQAIYDVNNIGHFGLGFEYYTHFTSPIRRYTDLLTHRLLKQALEGVNNLKPTMQQFYTNSAQWCSKTERIAVECERSLDKVKAARFMKDKVGNEYNGIVSGVTNFGIFVEIEDRGIEGLIRYAVLKSHYRYDEHEQAAYSEEDAKWYTLGDRIRIVVYKVDVKELFIDFIPASEFDNSFDDRDIIDSRDFLKKKKNKKEIYSRKSHKSSKDRKRGSKDRINRKERKKSKKRR
>NC_017243.1|WP_041177284.1|1243059_1245162_+|6-bladed-beta-propeller
MRIKLLAGIVLFLMTISLSYAFDKTPYYVNTETYDSYRELLRGVHYYNQERYDASIASFRNSLNTNPTDKFIRYWYSKSLYKAGYMSLAINEWLNITRMGYEDPIILSKINKYDSANVNEEKEDTLSNFIYLKAFSTNLNFRKNINQPIQIKVMADGSLYVLDYSDSSLKKFDINGRLIGKIAHGKRLEKQQTSWWKNVLQFVAKVYPYEKLENPRGFDIDSNGYIYIANTKKDKILKYDSNHNYITNIGVTGVSNGQLLGPSAVAVDKEGNIYVSDTGNNRIVVFDVEGNFLYSFGKLGENNGEFFSPAGIAVNDQYIYVADMGNKRIQQFDLSGNYIQTIKHNLFNEPRGLSFARDGNLYIADGSKVFYYDIVESEFTIFNNSERYTVTPTSVAESPNGNIYLTDFMSGRIDVYTRKEEYYANLDVFVDREYLNKFPVVVASVTVRDRAMNPVVGLTPENFFVTENSSVSHKVNFYDAPELHEYRFIYLIEDSLAAKAYESNIKEEISNFTMSLTNNDEVLVIHYNDQVYKADNYDARNLRILENANNFHFTGGISALDDAYYEAIRLSGNSFKKTAIIHFSVTSPDDRVFDMMNFNDVASFAKNNAVSLNQVYIGTNKSNYFLDLMTKNTYGYIIDADHSINYTDELDKMKNINFGRYFIYYNSFKNLAQSGQFRALNVKVQYRDMYGEEEVGYVVP
>NC_017243.1|WP_014487561.1|1242156_1242882_+|lytic-transglycosylase-domain-containing-protein
MIESVQRIHARIGEIQDTFNKLGFAPINTQLPTKPFAEHLNEAMAENNTENKVNNIDGSIVNDTNKKLDNGKVISGDTSSDAFKGNISFGVYDGATNNFAKAINAYKKASVESFPTKYDDIIKEAAEKYSLPENLIKAVIKQESNYVPTAVSNKGAVGLMQIMPQTGVGLGITDKEMLKDPYTNIMAGSRYLSQMLNRYNGRLDLSLSAYNAGPALVDRLQRIPNIEETQNYVKNIIGYIK
>NC_017243.1|WP_014487560.1|1241683_1242136_+|flagellar-export-protein-FliJ
MKKFDFKLEPLYKLRKNIEKQKQAEVAEVSALYNKERDGKDDCISKINDGIRIVDSMEDNNEMLTMSIYLGEYISALNSQIAIHEDNMAEISVELRKRQEVLQEASRQRRAVELLKEKKLLEYKKLMNKEEQAKLDEWKKEYVSSDAYEY
>NC_017243.1|WP_014487559.1|1240197_1241652_+|FliI/YscN-family-ATPase
MIKDENIDFDKEVKKTFEKYRKVVDDVALLKSYGKVKEVIGSLVISEGPFCKLGDMCRIYMNDDTYLDAEAIGFRNQDVLLATFGPVNGITFGNMVYSFERPLSVMCCDEILGTVLDARGKPLAGGGHNFYETPIPVSHNAVNPMNRPRIKKHIQTGVRAIDGLLTVGQGQRMAIMSGTGVGKSTLLSMIARNTNADVNVIALIGERRREVRDFIERDLGEEGLKRSVLVVATSDDAPLLRVRAAYTATTIAEYFRDKGKNVMFMVDSVTRFALAQREIGLSRGEPPTTRGYTPSVFSELAKLLERTGTSNKGSITAFYNVLVEGDDLDEPITDAVRGILDGHIVLSRDLANRGHFPAIDVNKSISRIMNEVVSNMHKRAAREFLKMSADYNEAKELIMIGGYAKGSMPEVDRAIDYKPMMDRYLQQDVYEVSSFADSKEALLSMFYSQEEIEEDLVNSGDVKKAADRTDISDNVEYANDVVIL
>NC_017243.1|WP_012670212.1|1239259_1240162_+|flagellar-assembly-protein-FliH
MPEKVFKSRSIVELTQKVNIAVPHHKSQEELDYEESQEEYRGPSIEEIEAEIAGLRAQWEEDLRDMRRKAVDEADRIIEDAKTQAFEIFKSKQNEAHVISEQAKVDASRIIQDANAEKERIQSESESIKDAAYKEGYAKGYDEGFEKSFSDSNNDLIKLTEKMKKILAETINKRNEIIDAAEAQVIEVAVLIAKRVVKMLTERDKGIVIRNIQEALRRIKGRTKITIRVNIDDLEVSARHKDEFYQMLDKIEGVTVLEDPNVDVGGCMIETDFGDIDARINTQLNEIETAIKEVEPIKGF
>NC_017243.1|WP_008724563.1|1238186_1239218_+|flagellar-motor-switch-protein-FliG
MPAEKEKDKKQRVLSGRQKVAIFLVSLGMETSSEIFKHLREEEIEQITFDIARLENIESADKDAVFREFQEMMIAQDFITQGGIDYARDLLERSVGSQKASDIINRLTSSLQVRPFDFIRRTDPAHLLNFIQGEHPQTIALILAYLEAQKAASILGALPTEIQPDVAKRIAIMDRTSPEVLREVERVLERKLSTLASEDFTSAGGIDSIVEIINSVDRSTEKSIIESLEEDDPELAEEIKKRMFVFEDIVLLDDRAIQKVLREVDSSDLAKALKSVDTDAQDKVYRNMSKRAAALLKEDMDFMGPVRLKDVEEAQQKIVNIIRKLEEQGDIVVARAGEDEMVV
>NC_017243.1|WP_014487558.1|1236426_1238130_+|flagellar-M-ring-protein-FliF
MQDFINKLTSQIKNIFAKTTTLQKAVLIGILVIGLGAIIATIMLTSRRTGTLLFQQALTQEDARNVIAVLDANNIRYQYRNGFITLNSEADKAKAELELVKEGRMPTGVDGWELFDAPRIGITDVELDINKRRSLTKAITQLLTKLDFVQEATVDLAFPKKEYLTDIDSPVTASVVIKAQPFKEEVLRDPKTVRGLQQLIAMGVDKLKPEFVTITDSTGYVLTDFTDEAANLKLKVAQEELKIVDRERKKIENKIRQTLGRIYTNRVETTIALELIWDDVSITNNLVLPIILKEDDPATPYDDSQFTNKVQVSTRTVTEDWKGQQFIPQGAAGAEENVPPGYKDKSDRWQTYTKTDSQDNYELSKRYEAIKKGSYQIGKISAAVALDGRWTKAYDQNGDPIITNGSSYVREYHPVTAEEIRNVTSLVQAAIGYDLKRGDQVSVTHIQFDHWDRFNAEDAKLMRDRFIRKTLIITMISLLILFVLALGIRAIQKELARRRRLREEELERKQMEMRRQAMMNANEEPISEMSLEDAARKKLMDEVIRVSHERPDDVAQLLRTWMADDKS
>NC_017243.1|WP_014487557.1|1235718_1236198_+|CinA-family-protein
MNYDKAKEVVDLLIQRGLKVTSAESCTGGLFAAHITSVSGSSGCFEGSFVTYSNEIKHRMINVREETLEKYGAVSEECVLEMAENSRKIMKSDIAIAISGIAGPSGGTDDKPVGLVWICLAAEGYIKAYKNIFSGDRQEVREQSVMFSLNLIENFIKKC
>NC_017243.1|WP_014487565.1|1252180_1253062_-|CAP-domain-containing-protein
MKNILILFILISYNAFTYNFVSIINDYRIANGKHPIKQNNQLDRALAKMAKMYAHKGYIDYEYISDANLNITDYSIVYTYGFTSSSSLVNFCVHNDNFLNNYDYASVAVYKIENYNYVVAGVFNGINYDDEVNEVYDLITENRNNNGAITKLKRDKNLEKMAMARAKELFEKYSHTRPNGKEFYTIMEDLNIENYWNGNGENIASGYKNAKEVMKAWMESKGHRENILDKRYTSVGVGLYVKNGKAYWVQIFGIDNPKYKDTDTEYQDNNNSTYDSYKNYDEYGDNYKNDSLY
>NC_017243.1|WP_014487567.1|1253596_1256353_+|hypothetical-protein
MKEINSYIEEISKADTQNLPIVYLLAIASENNADSTDLIRINNIVLLENKKLIYLKDLLNLFGNNFINIINDLLTKIDKEKYEIEIVYKEDNKDNKVLKISNLDNEELKKLKEKTRKFIIETIEKSKKDFKDYLFKLENWQENFNKDYFDLPFLYLLIIFRQCISDKDIYMYCINLGLDDNIINFIFADTKIYNIYIDESGKIINNEEFLVGGYFIEDINFRCWNEKARRLFYNILGKYSNNISNKKIIYHRNEIKNKKLKKNITYDVFNFVKINNGKFISICENKVKNNLFSRRYYISLLSELIMYTVRTIIVENKINLIDDKLLLIIKVSSRSYKDQYNSITFKFKDVEKFLTNAIDSKIEVSEILDKWKSDADQYLTRERYIEKLDISPVIYDGIEQVKIKYGLNTKNIDYEILDFEMASMTPDLVIADYFCNFYFNFIKVEELKNLIDIFGYMIYTNIEYNPFNSEIDFDFNMKDYYNILKRVILYKKISSSDKVTKYTREYSKKLVAKIIEYLKTDNHTNKNRYIVGALKSILENIEYQSDFIRNYSDIIDSYNVLIDLAKNNVLTNDKVLNGAIIFAINTGKLYVFNHADDDEKAREVVEDNKNYRDDVLKSVDFIDIVVLFDNISSIVYWYKYNTKYSIKALKQTLSNKNIEIEDYEKARLHGTLGQSYNINYYITNNTNDLINAKDAFIKAINYFNNNNLEIIREYSYLQNVAITAKDENEFLEYTEKYLNLISDDYKNIVELNNKIDTYLSLSNKDKGYEFFVIRLLRYCNTFKITKKSKEIANLLITNHKHFIENNIVSLEDVDIQKEYGLLLYKYNDGEIDTQYLKKCYSFMKGQLGTFNYMRMLSLYLIEILMDNESNIDKALSIIIDLSKITGAGYKIAFKGLHNKASIVNIKEWASNVRDKLYM
>NC_017243.1|WP_041177285.1|1256570_1256837_-|hypothetical-protein
MKKIISNIFSLIKSIIIIIILLHIADIFLFGNTLNIPKKGRQIFNKISQYDSKYFMDSVKNIKYHINNNFNKYKSKWENISSGNDKAV
>NC_017243.1|WP_014487569.1|1256860_1257229_-|hypothetical-protein
MSIISCTANTKPNIYHSLITIKSESHTRKPMSIYVSKTTENNYELMGIITTDKYSEEYDTGKDSYNISFYLDGGVYDIKFIWYEYKSVYPDPPYKDYKEYILQGKQIEKGINYKIDIDELIK
>NC_017243.1|WP_014487570.1|1257289_1258261_-|hypothetical-protein
MQKFYALSILFLMLFVSSLSANVNDYKNYRISIRPFNFDPNYDTYIEEIIESVLTDNGLNVFNRDKNIDKMMLEEQENIKINNPDAQSINKSLITHVVSGNIMKLEDKYICSISIKNINTYEPEKSVTKVLNDLSYNNIVKLSLDLYEKITGQQSHIRVETHQVLHNYKIQNTIPTKKISRIPAMVTGVLFIASGLAGTIYSSVELDSWHREIGGSAANEYYLYKNPNSSLSGVIQYRKLTLYNAWKKGEINTKPDNMPYFTPVGSSIILGTSIAFTIIGLGLFGWSLSDQPYFASNFDIKPTIFDENGCFDLGLQATFICKL
>NC_017243.1|WP_014487571.1|1258284_1258638_-|hypothetical-protein
MINELSNHEYKNFVILDKDIKYYRNEEIDYQSYNLNYENVNSFTNKYNAEYIMINKISRSPLNEYFLSSKMINMINGKIYLNKYEKIDNYEEFLTNSNVVLEKITNLAASISAQLKK
>NC_017243.1|WP_014487572.1|1258781_1259705_-|hypothetical-protein
MSIKEAKINAYINMADKYFYVGFKADSIFLDKYKSKNINIAYIPFLEENKSLQGYAEIFDIEFIEEKYNKEENKYYVFSIVNKIKLYSILKNRILKNENSINTYNEYLISEEDPFNRFVYLEMMYILSRKNHTYNKQIEYMNFECLELEHKYDDILPKLKEAENKLTFKVSPTGIGISKQIIDVLNYDINQYGFNISSDDNASYVFQINITLKQVEDKDTHRNNYESHFSLYILNNNVTIHTFQFQKIPEDNYIDNFEKAKDLVKYNVEKILREEFSIKLKEFLDNKIKIYNWSINNMKKYLFYLLF
>NC_017243.1|WP_041177286.1|1259887_1260295_-|hypothetical-protein
MKKTIIVSFIILMAIISCAKATNPEKKEISYFAGKYEGSMYFKYPNVIISENYTTVYINESESLTINNKYIHNDYYSTYIRKLALYSFKYTDNNSVYDGKIDILIANNSFTLTMTVSKDNEVLIPIFNVVKYNQI
>NC_017243.1|WP_014487575.1|1260320_1260773_-|hypothetical-protein
MFRFLIISMLITSSLFSETLILFPFNGIEHNDNISILEMFNEHISKTDTIKIINPPLMNYDFNSLNMKEYNEIMMNYAIKSNADYVLFGYLSYINETKKLNIKVMNIKNNNIIYSYPWSFEYIERIEYEISQKIYPDIVIKILDDSSMQF
>NC_017243.1|WP_014487576.1|1260853_1261363_-|hypothetical-protein
MRKKILYILLVLTVICSSAFAYNNNNKSIVVITFQGPVDIDNVTLSNLFEIELINLEGIKVKSGKGLYNSSYDRGKVSDSKEYYRSLYSSTYENEAIKIAKYLRSDYVLIGQINKLGNKKRLVIRVIDTNRNHIAGAQCTFENPEDIAGWIATMSKRIVDGINNSSKRY

Crispr_ID: NC_017243_7

• CRISPR_ID: NC_017243_7
• CRISPR_location: 1633280-1633376
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_7

Consensus_repeat	Method
TATCAAATAAAGACTCAGAGCTTTTGAATGA	CRISPRCasFinder

spacers of NC_017243_7

>7.1|1633311|35|NC_017243|CRISPRCasFinder
CTTTGAAGAGTTTAAAAATAAAATAACTGAAGAAA

CRISPR arrays and Neighbor proteins around NC_017243_7

CRISPR arrays

The CRISPR arrays of NC_017243_7

>merge|NC_017243|7|1633280-1633376|CRISPRCasFinder
TATCAAATAAAGACTCAGAGCTTTTGAATGACTTTGAAGAGTTTAAAAATAAAATAACTGAAGAAATATCAAATAAAGACTCAGAGATTTTGAATGA

>NC_017243|7|7|1633280-1633376|CRISPRCasFinder
TATCAAATAAAGACTCAGAGCTTTTGAATGA	CTTTGAAGAGTTTAAAAATAAAATAACTGAAGAAA
TATCAAATAAAGACTCAGAGATTTTGAATGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014487889.1|1649625_1650765_-|DUF3298-and-DUF4163-domain-containing-protein	unknown	unknown	gnl|CDD|378702
NC_017243.1|WP_041177323.1|1602059_1604186_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|185001
NC_017243.1|WP_014487886.1|1642435_1648252_+|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|234734
NC_017243.1|WP_041177325.1|1638814_1639636_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487888.1|1649147_1649486_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487878.1|1610252_1611503_-|histidine--tRNA-ligase	unknown	unknown	gnl|CDD|234586
NC_017243.1|WP_014487881.1|1638068_1638812_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487887.1|1648331_1648862_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487872.1|1604255_1605284_-|tRNA-2-selenouridine(34)-synthase-MnmH	unknown	unknown	gnl|CDD|236982
NC_017243.1|WP_014487891.1|1652912_1653977_+|CDP-glucose-4,6-dehydratase	unknown	unknown	gnl|CDD|274236
NC_017243.1|WP_041177327.1|1640133_1641516_-|gluconate-transporter	unknown	unknown	gnl|CDD|308194
NC_017243.1|WP_014487877.1|1609160_1610168_-|endolytic-transglycosylase-MltG	unknown	unknown	gnl|CDD|376862
NC_017243.1|WP_014487879.1|1611529_1613605_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014487870.1|1601213_1601915_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl|CDD|274750
NC_017243.1|WP_014487874.1|1606157_1606766_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177324.1|1608067_1609081_+|tryptophan--tRNA-ligase	unknown	unknown	gnl|CDD|234866
NC_017243.1|WP_014487885.1|1641569_1641881_-|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|376329
NC_017243.1|WP_014487875.1|1606960_1607944_+|hypothetical-protein	unknown	unknown	gnl|CDD|224688
NC_017243.1|WP_041177326.1|1639673_1640108_-|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NC_017243.1|WP_014487873.1|1605343_1606018_-|hemolysin-III-family-protein	unknown	unknown	gnl|CDD|224191

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_041177323.1|1602059_1604186_+|methyl-accepting-chemotaxis-protein	gnl|CDD|185001	PRK15041, PRK15041, methyl-accepting chemotaxis protein.	8.80841e-68
NC_017243.1|WP_014487886.1|1642435_1648252_+|excinuclease-ABC-subunit-UvrA	gnl|CDD|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_017243.1|WP_014487878.1|1610252_1611503_-|histidine--tRNA-ligase	gnl|CDD|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	0
NC_017243.1|WP_014487870.1|1601213_1601915_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	1.57059e-51
NC_017243.1|WP_014487875.1|1606960_1607944_+|hypothetical-protein	gnl|CDD|224688	COG1774, COG1774, Uncharacterized homolog of PSP1 [Function unknown].	2.09652e-56
NC_017243.1|WP_014487889.1|1649625_1650765_-|DUF3298-and-DUF4163-domain-containing-protein	gnl|CDD|378702	pfam11738, DUF3298, Protein of unknown function (DUF3298). This family of bacterial protein C-terminal regions is highly conserved but the function is not known. Several members are annotated as being endo-1,4-beta-xylanase-like, but this could not be confirmed, and the structure can be defined as a heat-shock cognate 70kd protein 44kd ATPase.	4.26935e-09
NC_017243.1|WP_014487877.1|1609160_1610168_-|endolytic-transglycosylase-MltG	gnl|CDD|376862	pfam02618, YceG, YceG-like family. This family of proteins is found in bacteria. Proteins in this family are typically between 332 and 389 amino acids in length. This family was previously incorrectly annotated and names as aminodeoxychorismate lyase. The structure of YceG was solved by X-ray crystallography.	2.87572e-105
NC_017243.1|WP_041177324.1|1608067_1609081_+|tryptophan--tRNA-ligase	gnl|CDD|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	1.22192e-177
NC_017243.1|WP_014487872.1|1604255_1605284_-|tRNA-2-selenouridine(34)-synthase-MnmH	gnl|CDD|236982	PRK11784, PRK11784, tRNA 2-selenouridine synthase; Provisional.	3.38087e-124
NC_017243.1|WP_041177327.1|1640133_1641516_-|gluconate-transporter	gnl|CDD|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	5.33075e-78
NC_017243.1|WP_014487885.1|1641569_1641881_-|HPr-family-phosphocarrier-protein	gnl|CDD|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	5.40873e-17
NC_017243.1|WP_014487891.1|1652912_1653977_+|CDP-glucose-4,6-dehydratase	gnl|CDD|274236	TIGR02622, CDP-glucose_46-dehydratase, CDP-glucose 4,6-dehydratase. Members of this protein family are CDP-glucose 4,6-dehydratase from a variety of Gram-negative and Gram-positive bacteria. Members typically are encoded next to a gene that encodes a glucose-1-phosphate cytidylyltransferase, which produces the substrate, CDP-D-glucose, used by this enzyme to produce CDP-4-keto-6-deoxyglucose. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	3.49367e-155
NC_017243.1|WP_041177326.1|1639673_1640108_-|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	3.21921e-81
NC_017243.1|WP_014487873.1|1605343_1606018_-|hemolysin-III-family-protein	gnl|CDD|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	1.2357e-50

Protein sequences

>NC_017243.1|WP_014487879.1|1611529_1613605_-|hypothetical-protein
MKKVIAFILLLYFPLFSQNSITFPDYIEDLQTKSPKKSIDWFKKNSYSDQYGVNEYVFDFYRGVSRYLSFVKFGSARTEVNRAASDFRKALELPNDPVYSYNDRAFLYLGGILTILPGDKELPARIFKYYADNCKTSNPHYPTAIYWSMYLSYITPMVYESYYETLNILSKNPNNKIYDYFSGENKPISEMMKKLKSPQDMTQKVYEWTTSNMDVYTLIKNSIPILPEEEGLSVFTAQKFDTFERYSPSKDIDEIEKEIEENEASEEDLVKTEIAPEEKEELDELQDIAKKEKTPENASNRKIPSIEKEIVDEIVIDDPKTIEYKTNILRGTKEQKDVPEPTNIETEIEDKPLYPLTILIDKSPNNGPIGVDIEDYSFNTEVSTNFVIEVSEGMYEAYISFGDKLYTNAVKVEKDKYNLFSIIIKDHTSTATNDIDSLKEEIKEELIDVDGEEEKEEVVEEKKEDVSVTVGKENTPVNRYDGNAENTRNIIREVLSRPAKVATEWFNTNPYNEYMGISVEEYTYYRGVAYYSRFLNEGRRSAEFAAQAKSDLTFAYNKKDNSNLLMRTRLYLGAVNLFAYNDLYEADKMFAEVGSSLSEDHRYYPTVLYWRSKIGVADAAKLEEFSKILSSKPKNTQILDYSSTMFKDLSSMPSYEEKITGIRAVGNSKPIYEPPKNTSKAGSTKTQEVLN
>NC_017243.1|WP_014487878.1|1610252_1611503_-|histidine--tRNA-ligase
MLDIKKPRGTNDFFYDSSKRLEYIENKIKNIVKLYGYGRIRTPLFEYTDLFTRGIGEGTDIVGKEMFTFEDRGGRSLTLRPEGTASVARAYVENSMQNEFAINKLFYLGTMYRAERPQKGRYREFNQFGVECIGNSSPLIDAEIILLNINVLKEFGIDDVNLLINTVGCSKCKPSYNNALKEAIGSRKEELCETCQKRYEGNILRILDCKNEKCKETIKDIPKFYDYVCDECKEHFDKLCEELTRIGQKFTVDPMLVRGLDYYTKTAFEVQTNALGAQSAILGGGRYDNLIGIFNNGKDVPAVGSAMGIERLLLVLENQNNIITDRLDAYIVAFKETENEVLKIMQALRANNISCDYDFAVKSIKSQFKSANKRNAKYAIVLGEDEFKRGMCKLKNMDSGEEKEISINDIHNNIEK
>NC_017243.1|WP_014487877.1|1609160_1610168_-|endolytic-transglycosylase-MltG
MKKLFIILIILVAIVSASSVAFIQYMISPISKDSEKVYFEIKQGEGASTIANKLELQGLIRNSKVFLLFAKYLKYDRKLLSGYYEVSRNMNMIEIMKHLNSGKQAMVRLTIPEGKNIYEIGTYLESQGFTTKKEFLEVCHDKEILKKYNIPSDSVEGYIFPSTYYIVKGNPTKVLVMYMIDSLFKQFPDLEERAKKMGRNVHEILTMASIVEKEMGPLDDPKLISSAYYNRLKIDKRLEADPTTIYAMTLVKGDYIEKPNLKYADLRMEHPYNTYKNTGLPPGPICSSGAKAIEAALDPADTDYIFFVADGTGKHAFSVTYEEHVENINRYIFKK
>NC_017243.1|WP_041177324.1|1608067_1609081_+|tryptophan--tRNA-ligase
MELKICQKKIMLSGIQPTGSLHIGNYLGALKNWADILNDYYGFFCIVDYHAITVEYDVSQMQKRIMDAAVEYLACGLDPNKCSIFVQSDVRAHTELAWIFNSIIPVAELERMTQYKDKSRKNVENINAALLTYPSLMAADILLYHPDIVPVGEDQEQHVELTRMIVRKFNNRYGEYFKEPDTYHGKVLRILGLDGQNKMSKSLNNHIALSLTAEETEKLIMQKAMTDTNRKLKTDPGNPDICNVYSYHKIFSSEDEQKEVCEGCKNASIGCVQCKRMLAKNINNELAPIRENINKYSNDKDYVYDVLKEGAKNASEVAEKTLYEVRNLMGLVDNKRK
>NC_017243.1|WP_014487875.1|1606960_1607944_+|hypothetical-protein
MIKNIAHIKFRGSNIGKFEHLHIENIKVKDACVIETDEGVEIGHVLNFEDIDVDLLEEENNINSDNIENNDEIHEDNETINEEEISEELKDIAAEEENNSVKVKNNKNKIFNILRIADEKDLEQYRINMEDAAEAFKICKEKVNNHNLDLKLISSYYFLDRAKLLFEFIAEERIDFRELVKDLAAHFKTRIELRQIGVRDEARSIGGCGICGRELCCKVIKGKFETITIKMAKEQGMLLNTMKISGQCGRLMCCLAHEYKAYCALKKDLPKVGTKLVFNNVPAVIKELNPLNKKLLIETEDKRLIYISVSDLKTNEEGFLIANIKAE
>NC_017243.1|WP_014487874.1|1606157_1606766_-|hypothetical-protein
MKLFLLFPLFFFMLSCVTAPEIYLNNNVIHWKEYVANKSSSDIYQNIYRFDKNADMDFIVYGYKSKIKYKLFLMKESDEAFYYKNTTLKSYIIESLPSLNLYEDALKNNDNSRLYINDYFNRTFSDRSIYLPIGLAFKDGDLYIAKTYGKDYQDRLSHWLRKNGYGTGKEWIPAINVDWNSYPVPIEHEIDWNDLEIIGKLF
>NC_017243.1|WP_014487873.1|1605343_1606018_-|hemolysin-III-family-protein
MEKSAFYIDVQNRYHKSKKIGELYSAISHGIGALLGIAGLVLMLVKTKVNPIPIIIYGTGIIFLYSFSSLYHFFPDGKVKQLFRKFDHIGIYVFIAATYTPVCIFSLPRNVGILILSVIWSCALIGILSNTVIKYKNIVLRLVLYILMGWIIIFAFKPLMNRFDIMHLNWLIWGGIFYTIGAFLYALGKKCNDKTKQFTHDIFHIFVLMGSFAHYWFLYSYVIN
>NC_017243.1|WP_014487872.1|1604255_1605284_-|tRNA-2-selenouridine(34)-synthase-MnmH
MVKVIDIEEFLKLANNDELPIIDVRSPIEYNHAHIPNAHNVYLFNDEERKDVGTIYKQIGRKEAILKGLEYVSVRMTAILKSIDEIAKKYNSTNKILMHCFRGGMRSESTAWLCSSYGYDVYMLKGGYKRYRNYVLDSFERDYKIYLLTGRTGSGKTLILNKLKSIGYNVIDLEKIAKHKGSAFGWINEGEQPSQEQFENNLSYELLKYDINSTLWFEDESLLIGRRAIPKSLFNKMREAQKIIYLDIPKECRAEYIVNTYGKYNIDDLKESILKIKKRLGGERLKESLELLDNGNIYECVLNMLYYYDKAYKLSINENKLVSIKCENNNFDNIVESIVKAI
>NC_017243.1|WP_041177323.1|1602059_1604186_+|methyl-accepting-chemotaxis-protein
MRKLQSLKVKIPFFVMLLVTVMTIILVTLIINIGSQGIRSSAIFGFESTTKVYSRMINVWLGQAIFTSEAISSGYPEFITYITTRTPESKAAVEATLKNIVANNHNVEGIVILDGAGNVIADNLDGKVVNTARNFSGTELWQKIMTGQSSMHYTVDPSPADNNKYVVKIFSPIKDSTGNIVGAISTMIDWLGFIDKELTLVKFGNTGHPFIVDKDRWVIADPIPSHVRSEVLRNADYIKYAVENESGYYEFKSPFNDKDSIATFYREPISGWSVVMSIESAELFSHITSMKRYAIIGTIIILVIASLVIVFYINKITTILHLLAIDLTSLSKGDLSWSTPPGFEKRKDEFGEIAVALINILDQLNEKVRIVYDGAYTVKASANEVAQGNIDLSNRTENQASGLEETASSMEEIASTIKSSAEHTLEGNNMMINSKKAIEEAGRIIEESTQNIEAVYESSSKISAITKIIEDIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQTTQTSVKDITTLVADSEEKIAAATETARESKEIFQNLRVQIEETAKIMQDLSSTAMEQQAGVDQVNIAITQMDMTTQQNAALVEEATAASEALFSQAEELLSAMEFFKLRGSNYKKNISKVERKKATPTTDTKAVQENKPAPKSEPQKPVTKKPELKSPIKKHHEEKMPAPTPARTVKDNEFGNTFDTSKDTSDGFESF
>NC_017243.1|WP_014487870.1|1601213_1601915_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MNILAFDTVSSSFSIALQKYDDSILEYNKEDVRNHNEEILPVLNNFLKENNISLDKIDYIVLGIGPGSFTALRIAFATVKTICYAKNIPIIGISSLETLYENIKSYEGIKASMIDARKGSIYTDIYSGNNKIKENLDITYEEFINIINSIENNDKTLTLCGDGFYKNQDYFKEKLKNYKINDIDKSFNIIKASNSIRLSIPRIKSNNFDNIFNLLPLYLRNSEAENKKMNEKQ
>NC_017243.1|WP_014487881.1|1638068_1638812_-|hypothetical-protein
MKKIFIFNIIAIFLFISCNEELITIVDEYNSPYAVYAIPGDNKVSISFWSGVIASDFAGFNIYAGTSPNFTQPDNAIKNSSGAYPTITGSNHTRTNFVREIPNYTFNNGTLYYVAVTAYGTNDLVDNKYIETTINATYPVIPRPEGTGNDAPALSANGNNVGNIDAAGGKVTPSSGWKVQYFGYQTNFNAVVIVTNNTDDAFDSEAVYSVNGLYIFKSGNQLAKIWIKSATSYQWAYQANASQWWGI
>NC_017243.1|WP_041177325.1|1638814_1639636_-|hypothetical-protein
MNIIKLFFYITISSLFFISCGLPDVTGVTLELNQPYITKVIPGQNKITVEFEAQNNEPSFSGYNIYFGDSTNPRKYRLYNQQKALPTLIETKSSTIKKYSFSIEVGSYFSTNSADIYTLKESDLNNGIPIYVWVSAYQITPQLESYYYYDNFVKMGTPRPEALNQTINVDSTINMEGRDLARLINDAGTLYFQNAANTSMMVMSGTSLNDIVVPPENGYGNINLSVKANRLYLIKIIDGNNAYYGKIYVRSVNGTSSITADYCRQTAANILSY
>NC_017243.1|WP_041177326.1|1639673_1640108_-|dUTP-diphosphatase
MLKIKIINKSDNPLPKYQTPGSSGLDLHANIDKPITLNKNDIVLIPTGLFIEIPEGYEAQIRSRSSLALKNGIFCLNSPATIDSDYRGELKIILASLTDVPFTINKGDRIAQMVFAKVEKASFEEVDTLSDTQRGEGGFGSTNK
>NC_017243.1|WP_041177327.1|1640133_1641516_-|gluconate-transporter
MISYFVIAMLAISIIVVMVLTIKFKVHPFIAMLLVAIFLAFTLHVPSNNDTNYITEISALIGKGFGNALASVGIIIVLGSVIGNILEMSGAALKLGEIVLRVVGKSHPALAMNILGFIVSIPVFCDSGYLILTPLRKAVAKKSGASPVALSVALSTGLYASHALIPPTPGPAAVVNLFGLEAHLLTIIIIGLIVAIPTSLVGAIYGIFISKYIKKPNYPDKSPTYETLISDIGGLPPTWKALAPIVVPILLMAIGSIVRFDSFRVGSGMIKNIFIFLGEPSMALFIGFLFSLLLTHKFNKEEISMWIGDGIRSSGSILAIVGASGAFAEVLKSTELAKIIPELGHIFGSLNMGLILPFIMASALKIMLGSSTIAVVTVASLFAPLLGTLGFNTPISQILVLMSIGAGSMIASHANDSYFWIVVELSGLKINDAYKARTLATFVQGITALIIIMILAFLFR
>NC_017243.1|WP_014487885.1|1641569_1641881_-|HPr-family-phosphocarrier-protein
MTLTNVVTIKSKNGMHLRPAGVLSQISSKNEYSNIGIFLLYNGVRADAKSVFNIMGLGAFQGANLILEIEYEEGMEEVAKQAEKELVYFFEEGYIHAEVPEDD
>NC_017243.1|WP_014487886.1|1642435_1648252_+|excinuclease-ABC-subunit-UvrA
MANNSIEIRGAKEHNLKNVSLSIPHKTLTTLTGVSGSGKSSLAFDTIFKEGQRRYLESLSAYARQFLGVMAKADVEHIEGLSPTISIDQKSVNKNPRSTVGTVTEIYDFFRLLFARLGIPYCSKCGHKISKQSEDQIAQSVLREFAEKRILVLAPIVRDRKGEYRKEIEEVKLAGYPRIRIDNIVYKFDEDEIPELKRYEKHTLEIVIDRIKVEDKYLSRITDDIERAIRITKGLVAFYEEHEKSEEVLETDTPENAEEDTKTKKKKIKMSKQFEIDKYYKLYTTERSCANCGHSIADIEPNLFSFNNPMGACTVCGGLGVEHVFTEKHIVKDENLNIYEGALSCFVDDHIGFDMEYGTDELEVIAKTYKIDLKKPWKDLTKTEKKYLLYGTDKEVKWRKRFWYHSKLVEERVPGILDRLKYDYETYKNSYYANFMDEVQCPKCKGKRINEDALSVKFNGKTIADFSSMTIEDLYDYFTKLKLKPNEEVIGSPIVKEIIYRLTFLVKVGLTYLTIERSSPTLSGGESQRIRLASQIGSGLEGVLYVLDEPSIGLHQSDNKKLIESLKTLRDKNNTVIVVEHDKETMEESDYLIDIGPNAGVNGGEVVGIGDYEEFIKSDRSYTAKYLRGDDDIEIPKQRREGNGKFLKVIGANQFNLKNIDVQFPLGLFIVVTGLSGSGKSTLVENILMRALHNHFYGKTLTPGSHERIEGLENIDKVIEVDQSPIGRTPRSNPATYTKVLSPIRDLFAATKLAKMRGYDKGRFSFNVKTGRCPTCEGAGVIELEMQFLSNVLVPCEECGGKRFNAETLDVKYKDKTIYDVLEMSVSEAITFFDGITSITRILKIMEDIGLGYIKLGQPSTTLSGGEAQRIKLASELHKISTGNTLYILDEPTTGLHFEDIKKLLKALDGLVEKGNTVLVVEHNLDVIKCADHIIDMGPLSGDKGGRVVAEGKPEDIINVKESLTAKELKEILKPSKKKKENIITEETKKEENTSLIIKGANKHNLKNISLTLPKNQINVITGVSGSGKTSLAFDTIFKEGQRRFVESLSTYARRFLGRFEDANVEKIEGLAPAIAIDQKNVSRNPRSTVATVTEIYDYFRLIFARVSKPHCPHCNDKNTLKAETPSILATEIVDTMDLHKLVIISPLYHSSFNHRFTFDDNDAKDIKKIIEKTREAGYVRMQINNNDYVIDDITEEDIKELSKEEIYSVGIVIDRIVVGKDKRARIADAIDRAMDLSNGVAHIKASHGIIVKESFHTKFPACLLHGILFDFEVTPRHFSFNSHWGYCEECKGLGSKPTFSIDLAIKDSTKPLFDGALDTAIHNMFSTPGKHYTDSLMRFLRRSGITKKDLYETPFNELDKKVIDAFFFGGDYSVGNVITAWHSNNDVTSEDYSEWKDQSLGKFFIDEECSSCHGERLNEIIRSYTIQNKNISQVCAMTVEENIHFFDELPNLLTERENTISKEAIKEIRTRLSFLDKVGLGYLFLSRKYATLSGGEAQRIRLASQLGSKLTGVLYVLDEPTVGLHPRDTNHLLDTLKELRNLKNTLVIVEHDRDTMKAADNIVDMGPYAGAFGGEVVFQGKYDDILKDDNSLTGNYLSERKKVFEKTAVRNEETECIKLKNVSTNNLKNIDVDIPLKKIVVVTGVSGSGKSSLIIDTLYPALKKRRLNQYSKFESVEIPSIVSDTILVDQISIVGSIRSTLVSYSKVFDKIRNIFAKTPTAKAKAFAPGRFSYNGKEGRCNICEGKGIRKIAMHFLSDMEIVCEACGGKRYNDETLSVRFKSLNIAEVLELTVDEAIEFFDFDKSIVKTLSIMSEVGLGYIKLSQRLDTFSGGELQRLKLATELAKKQGDEHIVYILDEPTTGLHFDDVNKLLIALNKLVEKGHSVIIIEHNPDVIKAADYIIDLGLEGGTNGGEIIAKGTVDQILEMKKGYTWKYI
>NC_017243.1|WP_014487887.1|1648331_1648862_-|hypothetical-protein
MKKTKNNDAAGAFRLLKLSFFIESLCRYIKGKDPDTIEAEFKQRCKKDGKWYSYDPNIWNGHPTDEEFEAYVEKLKSEGVEGEEDECTYWTEEDLAIYHEAEKLLYAISKTRENRRIIREGNIEENIFEYDEDTNELLKLLSDNNHHEALKKAKEIIQEDENPDEIMSIYHLTNNI
>NC_017243.1|WP_014487888.1|1649147_1649486_+|hypothetical-protein
MSDTKNKKEYKYTHLSTTVRITESELDLINKVVASDFVNKNQFVAFLLRDYLKKYTDENKQDDVNTLNTEDKSDNQNNSNISIADLNNSINILNQTISNLADLIKKDNTNND
>NC_017243.1|WP_014487889.1|1649625_1650765_-|DUF3298-and-DUF4163-domain-containing-protein
MKAIFLTVLCTLFIFVSCGNSNNTKQKTTSDNTTTEITPLQLSENEKANNYEVVYLVADTGEYINSEIAQNEKGNFGVIYYRDINQNLNTFNVTRAGELDEGNISATSYDNKTLEGNFPSTAYPFVAKIDGKEMTFKAAKTPVTGARIIEYTYSNVSPESSTNGQRFFQFKTAIFALKNDSKSASIDKVNLDINKDFGITDANTFNDLGKLLTAQSLISNKMTPIYDEWVKSDYISHIENYSSQFGIDYLSEKVVSINKMVYEYTGGAHGNYATINSVYSLETGNQLKIADLITDLKNADLIKLIVDKLVKIEGRDANSYFGLDELSLENNNFYLTSKGLVFTWGIYEIGPYAIGETRVLIPTEEIKPYLKDEYKTIFE
>NC_017243.1|WP_014487891.1|1652912_1653977_+|CDP-glucose-4,6-dehydratase
METLEIKEILKIFKNKNILITGHTGFKGSWLSKLLLEIGANVSGISLKANDLSLYNLLNLDNQLKSYIIDIRDLDNIKNTVTYINPDIIFHLAAQPLVIDSYNNPVYTFETNVIGTINLMEAMRELNNLECAIMITTDKVYDNKEWVWGYRENDSLGGHDPYSASKACSEIAIKSYRKSFFNNISIVSARAGNVIGGGDFADNRIIPDIVRSIEKDIPVELRNPNSVRPWQHVLDVLYGYLLLAYNIINKNSVSDSYNFAPIDEGNKFTVEYITKCFINNIGKGSYKINIQDTNKKEMNMLRLDSSLARKELGWNEKFNTEEAIKQTSIWYKEYLNNNDLNAITSKQIKEYIEG

Crispr_ID: NC_017243_8

• CRISPR_ID: NC_017243_8
• CRISPR_location: 2657551-2657648
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_8

Consensus_repeat	Method
TTATTATTGCTATGCTCGCCTCAAA	CRISPRCasFinder

spacers of NC_017243_8

>8.1|2657576|48|NC_017243|CRISPRCasFinder
CTATGAGCATAAAATAAATAAATTTATTTTATGTTTTCGGCTCGCTTT

CRISPR arrays and Neighbor proteins around NC_017243_8

CRISPR arrays

The CRISPR arrays of NC_017243_8

>merge|NC_017243|8|2657551-2657648|CRISPRCasFinder
TTATTATTGCTATGCTCGCCTCAAACTATGAGCATAAAATAAATAAATTTATTTTATGTTTTCGGCTCGCTTTTTTATATTGCTATGCTCGCCTCAAA

>NC_017243|8|8|2657551-2657648|CRISPRCasFinder
TTATTATTGCTATGCTCGCCTCAAA	CTATGAGCATAAAATAAATAAATTTATTTTATGTTTTCGGCTCGCTTT
TTTATATTGCTATGCTCGCCTCAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_041177443.1|2651749_2652412_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NC_017243.1|WP_014488751.1|2664731_2665205_-|glutathione-peroxidase	unknown	unknown	gnl|CDD|223463
NC_017243.1|WP_014488749.1|2662282_2663935_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_017243.1|WP_041177442.1|2651012_2651753_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014488741.1|2653944_2655039_-|streptolysin-associated-protein-SagC	unknown	unknown	gnl|CDD|200298
NC_017243.1|WP_014488740.1|2652386_2653733_-|streptolysin-associated-protein-SagD	unknown	unknown	gnl|CDD|274674
NC_017243.1|WP_041177445.1|2664160_2664589_-|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|293786
NC_017243.1|WP_014488743.1|2656441_2657506_+|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl|CDD|223411
NC_017243.1|WP_014488745.1|2658839_2659247_+|YbaN-family-protein	unknown	unknown	gnl|CDD|377291
NC_017243.1|WP_014488737.1|2649793_2650486_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_017243.1|WP_014488735.1|2647941_2648271_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367559
NC_017243.1|WP_014488754.1|2666550_2666697_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177441.1|2648754_2649471_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|378925
NC_017243.1|WP_083818266.1|2658036_2658702_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014488742.1|2655092_2656106_-|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl|CDD|380318
NC_017243.1|WP_041177444.1|2659263_2659869_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014488752.1|2665201_2665996_-|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl|CDD|236569
NC_017243.1|WP_014488753.1|2666008_2666533_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_041177440.1|2646603_2647266_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014488748.1|2660485_2662234_+|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl|CDD|227321

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_041177443.1|2651749_2652412_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.09109e-05
NC_017243.1|WP_014488751.1|2664731_2665205_-|glutathione-peroxidase	gnl|CDD|223463	COG0386, BtuE, Glutathione peroxidase [Posttranslational modification, protein turnover, chaperones].	3.94733e-81
NC_017243.1|WP_014488741.1|2653944_2655039_-|streptolysin-associated-protein-SagC	gnl|CDD|200298	TIGR03603, cyclo_dehy_ocin, thiazole/oxazole-forming peptide maturase, SagC family component. Members of this protein family include enzymes related to SagC, a protein involved in thiazole/oxazole cyclodehydration modifications during biosynthesis of streptolysin S in Streptococcus pyogenes from the protoxin polypeptide (product of the sagA gene). Recent evidence suggests that the YcaO/SagD-like component, not this component, performs an ATP-dependent cyclodehydration. This protein family serves as a marker for widely distributed prokaryotic systems for making a general class of heterocycle-containing bacteriocins. Note that this model does not find all possible examples of bacteriocin biosynthesis cyclodehydratases, an in particular misses the E. coli plasmid protein McbB of microcin B17 biosynthesis. [Cellular processes, Pathogenesis].	4.99525e-38
NC_017243.1|WP_014488740.1|2652386_2653733_-|streptolysin-associated-protein-SagD	gnl|CDD|274674	TIGR03604, hypothetical_protein, thiazole/oxazole-forming peptide maturase, SagD family component. Members of this protein family include enzymes related to SagD, previously referred to as a scaffold or docking protein involved in the biosynthesis of streptolysin S in Streptococcus pyogenes from the protoxin polypeptide (product of the sagA gene). Newer evidence describes an enzymatic activity, an ATP-dependent cyclodehydration reaction, previously ascribed to the SagC component. This protein family serves as a marker for widely distributed prokaryotic systems for making a general class of heterocycle-containing bacteriocins.	1.41503e-65
NC_017243.1|WP_041177445.1|2664160_2664589_-|ankyrin-repeat-domain-containing-protein	gnl|CDD|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	4.97727e-15
NC_017243.1|WP_014488743.1|2656441_2657506_+|Glu/Leu/Phe/Val-dehydrogenase	gnl|CDD|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	1.63626e-93
NC_017243.1|WP_014488745.1|2658839_2659247_+|YbaN-family-protein	gnl|CDD|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	3.72653e-41
NC_017243.1|WP_014488737.1|2649793_2650486_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.89611e-66
NC_017243.1|WP_014488735.1|2647941_2648271_-|PadR-family-transcriptional-regulator	gnl|CDD|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	1.46403e-20
NC_017243.1|WP_014488748.1|2660485_2662234_+|ABC-transporter-ATP-binding-protein/permease	gnl|CDD|227321	COG4988, CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NC_017243.1|WP_014488742.1|2655092_2656106_-|SagB/ThcOx-family-dehydrogenase	gnl|CDD|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	2.74708e-42
NC_017243.1|WP_014488752.1|2665201_2665996_-|nucleoside-triphosphate-pyrophosphohydrolase	gnl|CDD|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	7.4166e-118
NC_017243.1|WP_041177441.1|2648754_2649471_-|ABC-transporter-permease	gnl|CDD|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	8.66425e-08
NC_017243.1|WP_014488749.1|2662282_2663935_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.24045e-115

Protein sequences

>NC_017243.1|WP_014488743.1|2656441_2657506_+|Glu/Leu/Phe/Val-dehydrogenase
MEIFNYMEKYNYEELVFFNDSKTGLKAITCIHSTKLGPSLGGTRLWNYNNENEAIEDVLRLARGMSLKSACAGLDLGGGKTVIMADPKKVKGNELFWRSYGRFIESLNGRYITAEDVNTSTEEMEYVAKETNFVAGLRSKSGDPSPMTAYGVYMAIKASALKAFGTDNLGGKKISIQGLGHVGLVLCDYLAKDNVHLFVSDIDNDKVKKAVELYKAKEVDVNSIYEQDVDIFAPCGLGAIINDETIPKLKCKVIAGSANNVLKESHHGRILKEKGIVYAPDYVANAGGVINVAMENPTYNYEAAKTATEKIYNRILEIFEISDRENISTNEAADKLAMQRIESIGEIHSRYIRR
>NC_017243.1|WP_014488742.1|2655092_2656106_-|SagB/ThcOx-family-dehydrogenase
MKAKDKNLKNKLKKIEVSKEELEAKEIPLLFSVVNFSSNIPVSMYADTIGIKTSESSYRASMHSEVNRNISEEYLLNSKKSSIDLSTMLDVVGYSSFPIDASLSNRILLEEEVHKKGNAVKLPPYKNINAPIGSVIRSRRSRRDFKGKPLTMVDLSNLLYYGDGISGDFDFNLNKNEYGTITFSDKYISKLRTAPSGGGLYPIYLYIAALNINNLDKGIYKYMPFTHSLEKIKLFNDEDLENYYNNNVFGGGIDLRKTALSIYYVYSIYENSRKYGDMGLQFALIETGEIAQNIQLTAAASGILACDIGGFNKTLSEDLLNIDGNTNHVVHLTLLSK
>NC_017243.1|WP_014488741.1|2653944_2655039_-|streptolysin-associated-protein-SagC
MAKKNIKLYDNVSIFFNSDDEIRFRKGIWNFEEASLELSDLNDTIKEALIFIAKELFDDKLISFDDIVKKFSLNDKDSNFLNELISSLIGNRFLEYDDKKNNMLNTVYEFIGEYFYDIPDESKVQKNKIMFITDNDRLKEYAKLTSEDLYMNVIMMNADDIKKLEKANLTDTTDAIENMEKHKELIKLFDDISCVVVSAEKPRLNLLRNINRLLLDKSIPIVISILDGPFLNITTIKGKETGCYECFENRVVARNESLSVYNKFVKQTMNFKSNGKRTYITPILQTFTSLALYEAFLFATIGKCKLAGRVINVYIPLLEIQIQDLLRVPFCPACGNVSKAKYNEMYTSSKEIIENFSSKVILKL
>NC_017243.1|WP_014488740.1|2652386_2653733_-|streptolysin-associated-protein-SagD
MIKYYPSHKNILNKYNSICGHQTGIMDSLIIMQANSVIAENINTCTAMLPDYHKILLGDNAEVNYHLSGYGIYRDEAIIRLLGEGIERYALFTANLYFEEKLKYASYNQLKEKYPDNIIPFEYVKIYSDEDCNKLNSIGILENITEDDILSWVLLPSLFDKEKEYYVPAQNFFLSHIIRRDKKEKIFIGGFSKGSASHKSIPLALKSAITEIIECDSCMIKWYTDSKVKEIIIDDDILNEVINSILKDIDYNVRVFDYTVDKKLGYVFTVMLENKNEKSPYIVVGASSGLNPRKVIYRAFMEALAILTLNINGPLSMPADYLETVSPKNYLNLDSNVNYWADAENKDKNLKFINSKVQDKIELKKYKNLEVNTESDLEYLLKGLYNVSKYAVYLDITPSEISDKDLHVMRVYVPELVQMSMPAFPYSKHPRIIDNGGISNNEFPHPLP
>NC_017243.1|WP_041177443.1|2651749_2652412_-|CPBP-family-intramembrane-metalloprotease
MNFHTLYLSAFLVLLAISFPTSLIGIFYKLNFGRINTILPNSLSYLLFVIIVFFTGYIGSINYNISIYFVILSFIMSFVCIGIEIFEAMLIHFFKYRFWIKNIEVHEIIEKKNILFDIIIIFIGALCEEIIFRQVFFNITYNVFGINIYIVIILSAFIYSINHIYFGANAVFQKFIVGIIYSLLFVYSSFSIIAPVITHFLQNFILYILSFRRNKREALN
>NC_017243.1|WP_041177442.1|2651012_2651753_-|hypothetical-protein
MIFLNLLPYIAVSFILGIIIKFSERTNIINNICFKLMNHSRLEYNEMYVYVSTYIYWLLMIIFAVIISLIQKQNILLYLYIERKYIIYIFINIFAVISAFELIMSVISLINKDIRVNTIFNNILLVPSVDMLYSSRSNPKWTLIMFASIIKCLFFNGVIYSAVKMQFSDYGIFFTIFIVSMLFSLEEILRVNSIKQALIFTIACFVVITINALTFEYSGSLIPSVFANISFTLYYFGQFENISKYS
>NC_017243.1|WP_014488737.1|2649793_2650486_-|ABC-transporter-ATP-binding-protein
MEILISARNIEKKFNNNVILKNVNFDIHKGEIIALVGPNGSGKTTLINILLGILKADKGELKINIDNYKKHIGVQLQSTPFFEGYSVRDNILMFSALYDIKMSNEEIESITKKYGLNPKTPAIKLSGGEQKKLAIMIATMQNPDLLIFDEPTASLDPRERYNVKNMLLELAKNNKTILFTSHDLEEVEDLASKIVFLYKGEILESGSKEELLNKYNFDSLEKLYLHITNY
>NC_017243.1|WP_041177441.1|2648754_2649471_-|ABC-transporter-permease
MKTIFKLTMKKAIRDPFLIFWSIFFPLVIVISLGLFFKMESYTVHILTAMSCVSVLAYSFMTTSFNVLSQRRRGVYNLLKVTPLPLYKYIISLSCAWVIISIISCLFVFFVCALFFKLEFSFASILLFLPVIILASLLYIFISFFVSSLVKNNETASILYNIILMASMFLSDGYYSLYNAPNIVKILSKLNIFQYFLNAFRGAFYFDFHAYFIGIAVLLVCLIIALMLAVNTFRYADK
>NC_017243.1|WP_014488735.1|2647941_2648271_-|PadR-family-transcriptional-regulator
MYIESDIIRGHIDAVVLHFLKDNDSYGYELSKLITDKTNGEYEINGQTLYSAIRRLEGKKLIESYWGDESQGGRRKYYKITEEGKKFLQEEREIWLFTKKIIDKLLDIE
>NC_017243.1|WP_041177440.1|2646603_2647266_-|hypothetical-protein
MNINEFYKNIKKKYPNTKEVLEQLDEIKDMLNSKVQHYVKNGMKYEEACSKSIDELGNIDEVFEDISKDAKIVHNLYIKILTALISSFSTALLAFIVGLIVNNLSFFNETTKIGYKLTMPYFYLVLFIYIVIYSFWNFSDNIKPKIRKYSYDIYKINLKNSIIAVIIYSVIMIIVNIITYQYNNYLWFIWAFNGILNWTISIIADYHLFRSRIFEYTEKF
>NC_017243.1|WP_083818266.1|2658036_2658702_+|hypothetical-protein
MKTMIIMLILASLLYSYNSKDINNFYNAYYSSSYNIKTIENNNSQTYKNIYSLIKAKTMTNDKEKYNYLKEAINQNKDYEKSNDADYLISVSELMNYIVYYSGLSEKISFGSKSKDIYKKILETDDKNFFALLGTGVGYMHAPAIAGGSDKKAFQYFNDALSNAKEKYQKYLSYIWISQYYFKTKDEENYQKYINMCKEIYPNGELLKEALDRNNTKKKTL
>NC_017243.1|WP_014488745.1|2658839_2659247_+|YbaN-family-protein
MRILFISLGFLFMGIGIVGVVVPILPTAPFLLLSGFFFAKGSKKFHDWFISTNIYKKHLESFVKSKTMTLKSKLTILIPVTIMLSIAFIFINHLHARIALVVVLLIKYIYFFAYIKTTKEYSESIETNIELDKEN
>NC_017243.1|WP_041177444.1|2659263_2659869_+|hypothetical-protein
MKICKYIIIINIISLSLFEIAYTEEDKKNKLLSGLDNRFFSIGLYSSADTIKTSVNIEFGFKLFKYNNFEMKSYTSIVGSKIYDDNPDMYQLGFMQKFTFGNKDEYIDKITIARYAFTFVSFGFISFEPDKSGKSLFARPFYWEVGGGAGFNINVSKHVGIVLEFGGGLHDIFNGKSLGYPKKLNMAGFGRMSMGVRYYIY
>NC_017243.1|WP_014488748.1|2660485_2662234_+|ABC-transporter-ATP-binding-protein/permease
MINKRLISLMGNAKKYIAWHVIIQLVNLALNITAVIFMADIIQKASQGNVLKEDILKLAIAIFVIIILRFRFNILMANMSYHASGRVKQTLREKMYSKLLTLGSRYKEKFSTSEIVQISMEGVDQLETYFGRYLPQFFYSMIAPIVLFCVLSTISVKSAVILLICVPLIPISIIAIVQIAKRILKKYWGSYSDLGEIFLEDVQGLTTLKIYKADEKKNEEMNIEAEKFRIATMNLLFMQLNSTTIMDIIAYGGAALGVIISVLEYMKGNINLAGTFTIIMLSAEFFIPLRLLGSFFHIAMNGISASDKMFEILDMEEDDKRVNNINKENEEITFKDVSFAYNENKTILKNINMTIKEKSFVSIVGVSGSGKSTIAGLISLKNENYKGSIKIGSLELDTINKDDLYKKIVVVDHNSYLFEGTVYDNLKMAGDTITENQMNEALKKVELYDFLQTENGLNTVIMEKAANLSGGQRQRLALARAILFNADIYIFDEATSNVDVESEESIMQIIRDIAKEKTVILISHRLYNCIPSDHIYFLKDGIIMEEGTHNKLMSLNGEYAKIYNEQSNLESITKSESLSIAI
>NC_017243.1|WP_014488749.1|2662282_2663935_+|ABC-transporter-ATP-binding-protein
MRRSGIKIMAQLIGLITPLMHVMILAITTGVLGFLCAISITIFGGYAILTYLGLDSLFTIKTIFITVLVLAALRGILHYIEQLSNHYIAFKLLALIRDKVFKALRKLSPAKLEGRDKGNLIALITSDIELLEVFYAHTISPIAIGILTSLIMTIFIGSFNIVLGAIAFLGYFTIGFIIPYFSSKFGKNDGMAYRNNFGKLNSYFLDSLWGIKEILQFGYGEKRIQNIESKTDDLMDLNKKLKKYEGIISGLTTSAVSLFTLAVLIVSIMISKESNFAAIIIPTIAMASSFGPVIALSNLSNNLFMTLASGERVLNLLAEKPIVEEVYEGKKDISFNGVECEDVYFDYEGENILNDYNLEIEPNKIIGISGKSGSGKSTLLKLFMRFWDIKEGSIKISNTNIKDINTDKLRDMESYVTQETSIFKDTIENNIKIADQNATHEEVVEACKKASLHDFIMSLPNGYDTNVGELGDTLSGGEKQRIGIARSFLHKAPFILLDEPTSNLDSLNEAVILKSIKDNSENRTVVLVSHRLSTLNIADKIYKMKTDRVS
>NC_017243.1|WP_041177445.1|2664160_2664589_-|ankyrin-repeat-domain-containing-protein
MPINTNLYKRSKLYDLLSKIIKKKDDENFDLKDHINKLLELISKSTEEEVNYADNKISCLHLAVQIDNADVVAALIAKGANVNAINERGVSPLHTAIIKNQPEEVIKVLLDNGADYNIEEANFSALALAEIMNVPYMHLFKK
>NC_017243.1|WP_014488751.1|2664731_2665205_-|glutathione-peroxidase
MSIYDFNVKDINGNDVSLAKYKNKVILIVNTATRCGFTKQYKDLENIYEMYNSRGFEILDFPCNQFLNQAPESDEKIDNFCKLKYNTTFDRFKKIDVKGKNIEPLYSYLINNSNYLFNKDIKWNFTKFLIDRNGNIVRRFSSFSSYSAITKYIDKLI
>NC_017243.1|WP_014488752.1|2665201_2665996_-|nucleoside-triphosphate-pyrophosphohydrolase
MKSFEELISIIQTLRGENGCAWDKVQTFDSLIPCFLEEAYELVEAINNKDYENIKEELGDVLLHVVFFSELAKDENKFNIDDVCKNINEKLIRRHPHVFGDSNVKDVQGILKQWDKIKKEEKGTDGADEFKSVLDGIPKSLPIMEKSYKLMKKAASVGFEYEHIDDSLSKVEEELLEVKEAYKEQDKEHLEEEIGDLIMTVLDFARMNKINPVNSLIKVNEKFRKRFNYVEKTAYEMNKKLEDMSLDEMDQLWNEYKKKERENK
>NC_017243.1|WP_014488753.1|2666008_2666533_-|hypothetical-protein
MSELVIYLIIAVIWGIVSLIQKATKGNKQNKKPKQKTYTQNNKKVNNKRFNDNKNEEQIFKELQRNIKNLKNYNEEVLRENTKREEVYTSSYETSNNDREILELQEKYNSKMSQINAIKEETVSSDFNNIRTSENKRQVNHMLSSLDIKNAIIYNAILEPRRINYMRIKKSKLS
>NC_017243.1|WP_014488754.1|2666550_2666697_-|hypothetical-protein
MSNINLLLLIGFILLAVYSITTRIVNSRANKDKKENNNNYEEDNDSKE

Crispr_ID: NC_017243_9

• CRISPR_ID: NC_017243_9
• CRISPR_location: 3060791-3060893
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_9

Consensus_repeat	Method
AATATTTTACTGATTCATATACTTC	CRISPRCasFinder

spacers of NC_017243_9

>9.1|3060816|53|NC_017243|CRISPRCasFinder
TCCTTTTTCTTATTATGACTTTAATGTAAATAATATAAGTATTAAAAATGATG

CRISPR arrays and Neighbor proteins around NC_017243_9

CRISPR arrays

The CRISPR arrays of NC_017243_9

>merge|NC_017243|9|3060791-3060893|CRISPRCasFinder
AATATTTTACTGATTCATATACTTCTCCTTTTTCTTATTATGACTTTAATGTAAATAATATAAGTATTAAAAATGATGAATATTTTACTGATTCATATACTTC

>NC_017243|9|9|3060791-3060893|CRISPRCasFinder
AATATTTTACTGATTCATATACTTC	TCCTTTTTCTTATTATGACTTTAATGTAAATAATATAAGTATTAAAAATGATG
AATATTTTACTGATTCATATACTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014489086.1|3051111_3052716_+|flagellar-hook-length-control-protein	unknown	unknown	gnl|CDD|350657
NC_017243.1|WP_014489099.1|3063904_3064810_-|glycosyltransferase	unknown	unknown	gnl|CDD|275035
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	unknown	unknown	gnl|CDD|293739
NC_017243.1|WP_014489091.1|3055283_3055670_-|DUF1232-domain-containing-protein	unknown	unknown	gnl|CDD|377712
NC_017243.1|WP_014489087.1|3052790_3053585_+|flagellar-hook-capping-protein	unknown	unknown	gnl|CDD|236594
NC_017243.1|WP_041177499.1|3057585_3058767_+|N-acylglucosamine-2-epimerase	unknown	unknown	gnl|CDD|238153
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356
NC_017243.1|WP_014489085.1|3049918_3051013_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489097.1|3062697_3063072_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489089.1|3054198_3054795_-|hypothetical-protein	unknown	unknown	gnl|CDD|164795
NC_017243.1|WP_014489098.1|3063226_3063700_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489100.1|3064806_3067371_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489096.1|3061791_3062625_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489092.1|3055688_3056396_-|EcsC-family-protein	unknown	unknown	gnl|CDD|378945
NC_017243.1|WP_014489084.1|3049644_3049914_-|flagellar-biosynthesis-protein-FlhB	unknown	unknown	gnl|CDD|225166
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356
NC_017243.1|WP_014489093.1|3056528_3057401_-|DUF438-domain-containing-protein	unknown	unknown	gnl|CDD|225301
NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489090.1|3054837_3055245_-|hypothetical-protein	unknown	unknown	gnl|CDD|222810
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	unknown	unknown	gnl|CDD|368828

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014489086.1|3051111_3052716_+|flagellar-hook-length-control-protein	gnl|CDD|350657	cd17470, T3SS_Flik_C, C-terminal domain of flagellar hook-length control protein FliK and similar domains. The flagellar hook-length control protein FliK is a soluble cytoplasmic protein that is secreted during flagellar formation. It controls hook elongation by two successive events: by determining hook length and by stopping the supply of hook protein. It contains an N-terminal domain that determines hook length and a C-terminal domain that is responsible for switching secretion from the hook protein to that of the filament protein, by interacting with FlhB, the switchable secretion gate.	1.30525e-17
NC_017243.1|WP_014489099.1|3063904_3064810_-|glycosyltransferase	gnl|CDD|275035	TIGR04182, glyco_TIGR04182, glycosyltransferase, TIGR04182 family. Members of this family are glycosyltransferases restricted to the archaea. All but two members are from species with the PGF-CTERM/archaeosortase A system, a proposed maturation system for exported, glycosylated proteins as are found often in S-layers.	3.16826e-56
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	5.03223e-06
NC_017243.1|WP_014489091.1|3055283_3055670_-|DUF1232-domain-containing-protein	gnl|CDD|377712	pfam06803, DUF1232, Protein of unknown function (DUF1232). This family represents a conserved region of approximately 60 residues within a number of hypothetical bacterial and archaeal proteins of unknown function.	0.000128841
NC_017243.1|WP_014489087.1|3052790_3053585_+|flagellar-hook-capping-protein	gnl|CDD|236594	PRK09618, flgD, flagellar hook assembly protein FlgD.	1.69861e-25
NC_017243.1|WP_041177499.1|3057585_3058767_+|N-acylglucosamine-2-epimerase	gnl|CDD|238153	cd00249, AGE, AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is structurally and mechanistically distinct from the other four types of epimerases. The AGE domain monomer is composed of an alpha(6)/alpha(6)-barrel, the structure of which is also found in glucoamylase and cellulase. The active form is a homodimer. The alignment also contains subtype III mannose 6-phosphate isomerases.	3.06397e-63
NC_017243.1|WP_014489089.1|3054198_3054795_-|hypothetical-protein	gnl|CDD|164795	PHA00370, III, attachment protein.	0.00105627
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	gnl|CDD|368828	pfam06291, Lambda_Bor, Bor protein. This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the Escherichia coli host cell in animal serum. This property is a well known bacterial virulence determinant indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.	3.24795e-08
NC_017243.1|WP_014489092.1|3055688_3056396_-|EcsC-family-protein	gnl|CDD|378945	pfam12787, EcsC, EcsC protein family. Proteins in this family are related to EcsC from B. subtilis. This protein is found in an operon with EcsA and EcsB which are components of an ABC transport system. The function of this protein is unknown.	4.75201e-05
NC_017243.1|WP_014489084.1|3049644_3049914_-|flagellar-biosynthesis-protein-FlhB	gnl|CDD|225166	COG2257, COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown].	8.21771e-20
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.03733e-32
NC_017243.1|WP_014489093.1|3056528_3057401_-|DUF438-domain-containing-protein	gnl|CDD|225301	COG2461, COG2461, Uncharacterized conserved protein [Function unknown].	7.41414e-24
NC_017243.1|WP_014489090.1|3054837_3055245_-|hypothetical-protein	gnl|CDD|222810	PHA00684, PHA00684, hypothetical protein.	6.66641e-31
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.02463e-16

Protein sequences

>NC_017243.1|WP_041177499.1|3057585_3058767_+|N-acylglucosamine-2-epimerase
MSNLNEVKNEYLHMLKDNIIPFWLKNGLDKKHGGYYTALDRKGGLIETDKSVWFQGRFAWVLSTLYADFEKKQEYLDAAKSGIEFLEKYCFDKAGDGRMYFRVTEDGKPIIKRLRYYFSETFCLVAMAAYSRASGDKSYVKKAREILDNIDRYQKEGLLIPKFDAGNRPTIAFGPPMIMLATVQELRKADPENKDYYNKYIDNLLKNIQLFLYEDKKAVLEQCNPDGTLQDHFEGRLLNPGHAIESSWFILREAIERGHDETLKALGVKIFDWMWEWGWDKEYGGIIQYMDVLGKPKSEYHHDMKFWWPQTEAAIAALYCYYFTKDDKYLEKHDMVKEYTKKFIDTEYGEWFGYLHRDGRISTDLKGNMYKGPFHIPRMYMKCAEIIDAINAK
>NC_017243.1|WP_014489093.1|3056528_3057401_-|DUF438-domain-containing-protein
MTTLEFINISDSIYDLCTKYPKIKEALFDLGFDKIKNPIMFNTVSKIMTLEKAAKMKNIDNNELRKKLNEYGFELNSISNKEDRNDILKSLIVKLHCTGDIETIKREFEDKLIKVSAEEVHNAMHELIDNGMSIDEAKRFFYIRTLVLKDAMDNNTETNHKAIDIFEEENRCIEKLLNEIKSYDNINILNELYDNLNRHYIKKESLFIASLKKYGNDEPSKVMSRVDKDILNELKDIIDYGKNNKINSENIILLKEHISDMIFKEENILIPLCVSILSKEDFDNIEIKYS
>NC_017243.1|WP_014489092.1|3055688_3056396_-|EcsC-family-protein
MEEKSILSFIKMVSNMPLVKIDKHKYLVAAFASEYPSLLQTILEKGAYDAGVPLNIIDTKLREAINYEIAKSSAISFVSGLPGGIVGIGAVPADTAQFLCHALRIVQKLCYISGLPSFTLGDSMTDDEACLAAVYIGVMFEDKEAIFALNSIWKAIAEKSARIGFRVSSVVGYAVISSILKSIGIKIGSKSFMKSVSKAVPLIGGAVSAGFTYTSLNKMSNRLYNKIKESKYSIS
>NC_017243.1|WP_014489091.1|3055283_3055670_-|DUF1232-domain-containing-protein
MANDKNNKEDYVEINEDDIEILGEDGIYRKYEVYKRYQNKNKMKLRYWLPFITAVIYTLSPIDLIPDRIPIGKLDDILLLVISFMYGIKRANFSYNPIINIIIRNIILSITITGFVMMIIIYILAALL
>NC_017243.1|WP_014489090.1|3054837_3055245_-|hypothetical-protein
MNRISSSNITKLEDNEVFVFGSNTQGAHGGGAARFAMNFGAVYGKAFGLQGKTFAIPTVDYTKSGKMAVSEIKKYVDKFLAFTLEHKDLKFLVTEIGCGIAGFKVEEMAELFREALKDEYDNVYLPQRFVDYLKR
>NC_017243.1|WP_014489089.1|3054198_3054795_-|hypothetical-protein
MKTKIFILLMILILAFSCSKNNPVSALGTGSDTGIESGGTDTGTEEGSGGEDTGTGTGGEDTGTGTGEGDTGGTDTGETTIGIIYAGTYTGKAVKTRINNITEEEKVVEDVILVVNKDSTAIFKTASLGDYTFEKFEKIANNDSLYESIKSDTMLFLSFDKNTVTVNFIKKESSRESIIYGNGHEYDKGYGDLTKADY
>NC_017243.1|WP_014489087.1|3052790_3053585_+|flagellar-hook-capping-protein
MISADALRMSDKEIKILKQEVGAFNLQHNFQRDPTQNSLGKDAFLKLLTVQMSHQDPLAPMDNRDMIAQLAQFSSVEQMTEVNKNLDSMKTFYSSQTGYSMLGKSVEVMDEAGNRFLGPVEMVMENDTGVALAVRTDNGLITVRPEDVMIVHSSGDLMASEAAAVSQVREAQSEDEAAKVFESSLIDKAQIIRPSGDENNGEGINNEFGDMRAAIEAEINSATQSEVSKTDNANLNKTEKTVGMMKAEEALMNSKESGNKTIKK
>NC_017243.1|WP_014489086.1|3051111_3052716_+|flagellar-hook-length-control-protein
MVNGLGNLLSFVDTNVSSNNSPYNLNNYSYDDSFANMLNKTQTDYSAPSSVSNKIERHLNTEENQTENNYNSYDDYYNDYNQYDAEENTTIEEKVSSSSENAAKKTDETSDNAEEAKSVNNAEEQAENKSEELNASSNKDNIEAKAEKLASGNKEENVSAKEKLALTKEKAKLLLQNTSNDKKADAKEVNTSDTKENILAKADKKENTKNTEEIEKIKKQIESLNAEELSEEDEKELEDLIDSLEALKAMIENEGSEDKKEVLAENTEENIEVKDIDNPEVKEIKVASNKDNDKNIETKDINDINIEDNAMQVDNNAMADANIDMNIENKYADKKDAAEMKNNNSTVNNTISDDKGAELTIINMKDSAEGANLKGYNHYNNNVSKTHNSTNLTDNMIKFQDLMGKLVEKAQVAVNNGKSEVLMSLNPEYLGKVRLKISMDGDNLIGKIFVDNADVKDIFTKNLDTVITSLSEIGINIEGFDVMLRQDMPNDGGFGEELEAIGNRFASENSNNVEEVKADIKAYIVPERKLNLLI
>NC_017243.1|WP_014489085.1|3049918_3051013_-|hypothetical-protein
MFYNDNMLNINSKYFNLITNKNNAQIKDGDVVRYSIMRKLDNDKALINVMGNKLIALFKNGMTDKGFALVSKKNGEVTLTILKNAESLKEAREGIQNKNNANVLLNITENNSEVSTMLSQKGIKPSHENIRYFETILKYLPDLDSDKKKFILNAMSNGVYLTVEEINSLGNIFKQFNDIIGYIKNSNKNTEITEILLMLANSVIQGDDNNSNNTIAENLNNYINTNASFNIWFMLFDMLHGELSSDNSNMMMLMLKILSANRKNRNFNETAFMIPIPFVIDGEIKDVLLYISKDENNKNRLTFVVYNDDKELCKIDITKDEYENKYLITVKFFDKKLYNKLNRIKEDMEKELSIFDNIKMNYEG
>NC_017243.1|WP_014489084.1|3049644_3049914_-|flagellar-biosynthesis-protein-FlhB
MSKDNKDIKNAAALLYNREMHNAPIVISKGNNYLAKRMVDIARKHKVPVISDENTAKHLMQLEIGEEIPYSLYEAVSIILKYIYKLKAE
>NC_017243.1|WP_014489096.1|3061791_3062625_+|hypothetical-protein
MFSLRNELRKRDLETLDLFTLAFSLFKQNFINFIILSLICCLPLILTGIYFPISTFDPEKLKTYEDLINWFKNDVTIGFYINIFLSLFLDTISIISVSLLVERLIYRNVKSATWAIIRSFKFLLPTIFTTFIYFILVFLGLTFFIVPGIAFIVFFVFIKNICALRHTWGIDALKYSFYLVKPKFFKTLFLLGFIFLFQQVFAMTLFPSSLENREGLLSYFIAMIVLYIFNTYFQIITTLFFLNRDYVSSSMQENEDDEYDDEEENDGNDNDENDIEK
>NC_017243.1|WP_014489097.1|3062697_3063072_-|hypothetical-protein
MIKKIALFYLFLFALISCNANSDGSTSASAKYKEAPRESKGLTNFTGIWNAKFPNNESSIVIENGENVLYNDLKASSIEDLGNDRYKMTISADKTFSVTLKFKSDTEGTVEDDNLGIGTLAKSE
>NC_017243.1|WP_014489098.1|3063226_3063700_+|hypothetical-protein
MNTKYNKEIENQIYEIIKKDNPTFEEISKKLNINYDDLKNYINKSSKKYKKSLVKKIRKAKEEYLKDVKIKIENALIKKALGYYSKEIVREIKTDKDGKESKTKKIINKYNPPSERAIIVFFEILKNRNNKRLEKAELKRNIQEEDSRINIKVGFDN
>NC_017243.1|WP_014489099.1|3063904_3064810_-|glycosyltransferase
MKISVIIPCYNEEITIKQVIEEFRKYLPEAEINVFDNNSKDNSVKLAKEAGTIVTEVNYQGKGEVVRRAFSDIDADIYIMVDADMQYDISEIKKHIEYFLDKKLDMLNIAREVVDEDVHRKGHTFGNAMLTGFANILFGKRFNDMLSGYRIFSKRFVKSFPAASKGFEIETELTIYALQMRLSVGEVPAKYFKRPEGSHSKLNTFRDGFRILFTIIYLMMTEKPIIFFNIISIILFIIGMALGISITIEYFETLKVDRFPTAILTICLLILSALSFAIGLIMNAIGRVISENRRFKYNSVK
>NC_017243.1|WP_014489100.1|3064806_3067371_-|hypothetical-protein
MKNKLKKISLTTSIILLIFILFLIVLGNISRKGYFSDFNLKSHNEGKYTYAFRINYYNKIFRNNDIYGVYPNIQSILNNNKHIKKIDMNDYNGTPFGTLVTAKKLNVDEKIDNIDYKLQIKPIFFLIFCISIIYIICNLKSFNIYKNIMKIIYYFNNFNYRNIIKKIIIVSVPLFIFIFVLLFILGKNDRIGYLSDLNLNIDNTLKINNFNVNATKKLFTLKNTLNNKELLNYIYTNDSITNYSYNFEIKYYSKIFKNSDFYEVYIDTNKSINNNIFIKKIDMNNTIGTPFGILASDKVINENKIDNIIYTLKIKSHIIYAIFLIFFILILCYLIKVYCSITSFKSNNINGLIIKEDNIVYMLKNDYYFLFSLILIFIFLFYFIYWLFFPGYYQYWDTSEVIWRAYTENYDNWRPIIISLVLRILYSIFGYDTYYLFLINILSWFIGLYLIIVSLYTKFKNKLVILLIFLSFLGNIFFTKINSEKDFTATLILWLSLSIIFYSITGNIKNPKILFFTKALSIFIALIALLWRHNFIVTVYPILFIYLFINIEKINNVKKFILSIISIMFVLGISLIIMVKIFPLFFIDEDRAKTATYHTFLIQISACAVDSNDSNLIPKNWYLDGRNFEDVKKIYNTERGSVLADLYAVNFDRNAPFKILPPNPNIKKNIKKVWVKAIISHPISYMKHIYNYAKYIFTTEDWSTFLRKLNYRFDPEYIQQTYKFPFMSNEYYNSIHNKNIQFDKNKEKIYSFFYRYLPDINISFFVILSFVLFFISLFCMFKFNNNFLIFSFLVSFSSAATCIIVLLFSPAPLYRYISPVVHISIISLISFITFIYDIGGLKIFIKKLRSNSNI
>NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein
MKQNKKTFLLSYLVFILAIILFIVIFSILGSVERVGYLSNFNHILENKYYFTLKFESSIFKNNKIYRVYPNTNEMPDNVTNIRWSGSYYGNLVLGDSSIQLKENDKIENIKYTVKIQKNVFLFLLFIIIVFPAIYFYVIPNIYYHHKSYIFFFVLNSLLYLITSNLIMPLFSMMKLDFNIYDFLYTYLFVMIAYNLLVHYPFNLGNIKNIRIILTALFCVVSIFSFFAIESISLTVLSMVILFSDMPNLYSSLITVLPMHLKIITITVSIIYFSSLLAFVILFIFNIYKIFVERNKIASLVMIAFIIFTVFYLFLKPKNIDIWSIDFVRNAKRNGIINTLNYRINYDRLNNIKPSKELVSDSIKLLKEYESKRDVSKLYLKSTKNIFDNIKKIEDDMHSILIEASSKNSNFVYNNENIDYEYIEQLKNNYYDVYTNFEISITNDLSKIEELKKGLKRDVYLIFLESFYDYSHFRKLFNKDPFPKEYRKWADSSRKIAPNVNNGSFYARLSGLTGSSPLYPKTQSEKIENTLPDILSKNGYNTIALEEALNTYNLKTFYPSIGFKSQLFGLGTTNINTYLGTNIDNLGSPVFAAGFTILGHTDSHLSNDLNFAENNKKFLDNFEGNDKLHIIETIDNSAMTAINIIEIRDTILKHSPNAIIIFKHDHLYPYLKAIIERSSIDEKIKTNFLNDYKPSPVLIWDGTNGAYKAPENFTPENIPLFIAANLNVDYTNSVISLLYKEEIDDTISTYNKFYHTTNDSLIDNSEVSNMMIFKYENAQRTLSQDIFQGKKHYYNFIK
>NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein
MVKMIILLSIISIFAVSCSYQHRHLVGNGPQTGVTLTRKQWYALWGLVPVNDVDVEKLAGGSENYEIYTRSNAGDFFINLFTGIIGFTSRTVTVRK
>NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein
MKTLYFIITLFLISCTNNSYKDIFSNRDINFKKLSLDNDILYQNKYDISDIKVKLMPLNNSVRLTDEDKNHIIKNTGYVKDLYHIESIFWEENTQTTCLVGYMKKDNNSLEKLINYINKMERDNNILKNYFYINGKKNIQYKIQLENTVLFYTIFEAKDSKYLVLSYTFPEKNEYASMYNIANSINSVEFY
>NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein
MDKEIEDFNKDFDDEIFDMAFVLKRSCCKYNKIPWDKYYTLFVSAIALKNISANVIIENTHIIIHKKVKEPEEYLKILKDESIVKLKVRKEKDPDDFYIRFLLEDIIDTNYKDNDLNIILEKYSEIIYYKDEELGDFVLNKDINSFKKEMTWTESNISIFFDNIDEEFNKQSVDIIKKIFSNKKDIDSKLKECAAESIFKPHNMEREEFIKLISLESISIYSKNCITFYFDDIDGHTILVNSDWDFNFKPITELMFF
>NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein
MDKEIEDFNKNFDDEILDIAFVLKKQNLSAGKSKGKYYTLLVSAIAYKNIITNEIIENENLLIVKEIEDTKHYFQIFRNKTIVRLKVRKEKDSSGLYMRFLLEDIIDTNYKDNDLNIILEKYSKPVYYKDEELGDFELDKSINMFNKNIEWDNNNISISFENIDEEVNKKSVDIIRKIFASKKDIDKKLKEYISENLIEDANTWNDDDDKPHISKEEFVKLITLTSITIIYENNITFYFDDGDIFSRHVIAVDSDYDFNFEDAHIEG

Crispr_ID: NC_017243_11

• CRISPR_ID: NC_017243_11
• CRISPR_location: 3087980-3088051
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_11

Consensus_repeat	Method
ATAATAATTATTTTGGTATGGAT	CRISPRCasFinder

spacers of NC_017243_11

>11.1|3088003|25|NC_017243|CRISPRCasFinder
CTTGATAAGTATTATCATAGCCATT

CRISPR arrays and Neighbor proteins around NC_017243_11

CRISPR arrays

The CRISPR arrays of NC_017243_11

>merge|NC_017243|11|3087980-3088051|CRISPRCasFinder
ATAATAATTATTTTGGTATGGATCTTGATAAGTATTATCATAGCCATTATAATAATTATTTTGATATGGATT

>NC_017243|11|11|3087980-3088051|CRISPRCasFinder
ATAATAATTATTTTGGTATGGAT	CTTGATAAGTATTATCATAGCCATT
ATAATAATTATTTTGATATGGATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase	unknown	unknown	gnl|CDD|234947
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	unknown	unknown	gnl|CDD|293739
NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase	unknown	unknown	gnl|CDD|335802
NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein	unknown	unknown	gnl|CDD|379270
NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin	unknown	unknown	gnl|CDD|153100
NC_017243.1|WP_014489107.1|3073758_3076242_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381297
NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|379179
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	unknown	unknown	gnl|CDD|368828
NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase	unknown	unknown	gnl|CDD|153228
NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase	unknown	unknown	gnl|CDD|239945
NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein	unknown	unknown	gnl|CDD|237177
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356
NC_017243.1|WP_014489115.1|3089654_3090560_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase	unknown	unknown	gnl|CDD|240363
NC_017243.1|WP_014489113.1|3088548_3088962_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase	gnl|CDD|234947	PRK01362, PRK01362, fructose-6-phosphate aldolase.	1.13091e-142
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	5.03223e-06
NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.45176e-67
NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase	gnl|CDD|335802	pfam04466, Terminase_3, Phage terminase large subunit. Initiation of packaging of double-stranded viral DNA involves the specific interaction of the prohead with viral DNA in a process mediated by a phage-encoded terminase protein. The terminase enzymes are usually hetero-oligomers composed of a small and a large subunit. This region is found on the large subunit and possess an endonuclease and ATPase activity that require Mg2+ and a neutral or slightly basic reaction. This region is also found in bacterial sequences.	1.47436e-22
NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein	gnl|CDD|379270	pfam13569, DUF4132, Domain of unknown function (DUF4132). This domain might be involved in the biosynthesis of the molybdopterin cofactor in E.coli.	3.74866e-57
NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	1.25265e-47
NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein	gnl|CDD|379179	pfam13428, TPR_14, Tetratricopeptide repeat.	3.83113e-05
NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase	gnl|CDD|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	6.73503e-139
NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.02463e-16
NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase	gnl|CDD|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	3.9814e-71
NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase	gnl|CDD|239945	cd04501, SGNH_hydrolase_like_4, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	8.80273e-40
NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	1.90547e-08
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.03733e-32
NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase	gnl|CDD|240363	PTZ00331, PTZ00331, alpha/beta hydrolase; Provisional.	1.40038e-05
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	gnl|CDD|368828	pfam06291, Lambda_Bor, Bor protein. This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the Escherichia coli host cell in animal serum. This property is a well known bacterial virulence determinant indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.	3.24795e-08

Protein sequences

>NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase
MSVKIPYEKIVNEDFIGKEVNPINQQDIYKIALEYSNEVIKEFEDESINLLIVDPQRDFIDMEKGALPVKGAVDDIKNIIRFIYDNMERLSSIYVTLDTHRYDSIFHSIMWNDFNDKPVAPFTEITLEKILNDEIIPVYDEEIQINYVKALKEKNAQNLMIWPYHCIYATDGWLIDKQLANILLFFETSRRVYINKILKGQDSFSEMYGVIRPEVPTEYTKNYDTSWVYDIANADKIYICGEAKDYCVYESVKQFCEIYHNDKSVTETINIMMNCSSAIGDNKACEQKYEELSSKYGIKLLNI
>NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA
MNKEEAKQKIEQLTETINYHNKLYYTDDNPEIEDYEYDKLFRELENLEREFPELKKDDSPTNKVGGTILEKFEKFEHPIAMYSLSNVMNEEEFLEFDNRMQKELNQSKIKYTVENKFDGLALELIYEKGKLTVASTRGDGQVGENVTNNVKMMNNVPKSIKEKKKLIVRGEALITKKDFEALNKEREELEEIPFANARNAASGGLRQLDSAESKKRRLKFFAYQIANYKDFDLTNEYKSMEFLSELGFTVEGVHPNIDAKKVLETYYDIQEKRSKMDYEIDGLVIKVDDVKHQEKLGFLSRAPRFAVAFKFKPEEKETVLKNIEVQVGRTGALTPVAKLEPVQVGGVTVSNVTLHNPNEIKSKDIRIGDTIVVIRSGDVIPKITRVVLEKRPADSKPFEFPKKCPVCGGDTAVTDGDVIVRCINEECPSKITRYIEYFVSKPAMNMERIGKEWIAVFTKSGLVKTPADLYKITRDDLFKFERMGEKLAGYMLESIENSKNTTLKRFIYALGIRQVGETTADLLAKYFTSIDNFKKATIDDLQNIEGIGEISAKSIYDFLHNEKTLKLIDDLLAAGVNPVFEKVVTVESPLTGKNVVITGSIEGFTRNSAKEAAERLGATVQSAVSKNTNILIVGEKAGSKLKKAQDLGVEIMEADKFIKLANG
>NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein
MSDNTNNLNNRNNTTFILYIVVCSIFLIALIIIYLLFSSSIKKSMDYSIGKFETNSQIQLSNYYEFLKEMVTNESFENKEFIKNTLEEAFKPNIDLLRETLKDSKDFSINTVTFWLAFLSLIMIIFTILGIYANNKIMESNQKQSELIIKDLESKAENSFNNIGELVKENKEYIENLKSDFDNIKNSLLSEMETIKDDAIKTKDNTLNEVNSIKKEIDSNKKESEDLKSEIYEIRDESKKLLKEMREERKAQSEEGKNIIEKIKIEGNTQKEEAKDLKSEIERIKEEAEKMLKEMKEEREVQKEESEQTLEELNKKAKEIESTLKKIEKQTKQSKINADRAKVSELFNRALRENDKNNKEKAIKLYTEIINEYNSNDTDSLNNRGVLYSDKYKETKDEEYFDKALEDYNHILRIDNNDYGTYINMSFLYLNHYEINKENKESLTQAEKYLNEGLKLYTNDLELINNYGILLYFKYKEDKKTVDLNNSEMYFNKSIGNTRTKENIGETYYYLHLVYDEYAKLDENISGYSKEECEKKSKEYLQKSKDLGYKHFMDK
>NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein
MENNISNEEQIRNKFERIFQYENNKNAFLDYFYGRSNSCPTLRNYYGYEAEDIFKFYFDENTKEEDKKALSRYAEAIIKDIYKNQNVHIILRLSTGEDLEKALIESYNNTYERTIYDKKYSKATLLNNEASKYIQIQVNNFYKFSELEAYVYKDFNQYLEKVKNDNKALLNKEPRLLLTILVYLINRDDDKSLIKQLLNYIDLLKINYEETISLLFTIVDKDEEVYKRLMNILNKDNNMIYFLVNIYKDMTRTIKLYKRLFKGYSEDKGYYYYTQKLIPEYLELCNFPKECILLNTIVNNNTLFISYLTVEAKKLYDEDKETFYKLYEIIEKSKLENLYLDYAMLSSIMLASGDNKYNIDTNSIVETLKTMCVELLKIMQPIQSFDEITSKSFKYVKEEPYTNHSHYLSAIMSFDGINDEASEITTKLLKHYGIYGKISIYVSIQKIFYNRNILEAKEKLVNDKKVPLKDIYLSLLDSKDNIITLIKNNVEETKSIMEEKSFITSITANISGTISFINCIFSDELSGLIDNKFDFVFKVLDTAKSKEIKKHCVSVISNNESIVRSKVEKLANEGKEASRTVYKEIIKYWDLQKFDDDFQFTSVDEINEYLNKYYNEGHESLIKDIDENILSNILLKDKKTKAPLKIVQYVFMEYVALKEPSILKDCNKIAEFFDIDSFRNALDNIYTNWLNNKADTKLKNILIPYCIFQPEDKLLKLKTQIEEWALNARGALAAHAVYAIALNASKFALVLVDTMSVKIKNNQVKNAAKDALKKTAKALEISEDELIDKIIPDLDFDKKGMRELHYGGEANRVFKLQIKNDFTIEVTDSNDKVLKSLPAPNSKDDKETADASKKELTLIKKNIKMITSNQITRLNKVLLNGRKWSYKTFTELFVENPIMNIFALKLIWGVYDEKNNLIESFRYMEDGSFNTFDEEEYIFEDSLKNKKNITLVHPIELDEEQLSKWKTQLSDYEISQPINQLDLLFEEVKEEHIKNNKIISFEDQEITAGEIMSMANKMSFERSRDIEDGGSYTYYELKDSILNIACRIDFEYMWFGIEANEKVTFKNIAFHRLDENGNCNAEEYINPLDINKRFTSSIYGTVKSYFMK
>NC_017243.1|WP_014489107.1|3073758_3076242_-|hypothetical-protein
MKNSISNEEKIRNKFEEMFSHENNKDAFLDYFYGKSNSCPTLSKNYLYYAEEIFKFYFDENTSKGDKEVLSRYAKVIIKDIYKGNPNPNYIIITTYMIVRLCSGEDLEKVLIESYNIDIEEIYIDDKKYSKSQLKNNKGYEYIKIQNKNFNRFLILENYIGKEFNEYLEKVKNDSKVLLEKEPHLLLTILVYIINRDDDKSLIKQLLNYIDLLKINDEETISLLFTIVDKDEEVYKRLINILNKDNNIIYFIVNLDSVMITNIELCKRFFKKYSEDPTYHYFEAREVADEYLEICSFPKEYIFLNKIYCGGNTHCTSSLTVELKKLYIEDKTTFYKLYEIIEKSKLECLYLDYVVLSAIMLAVNDNKYNINANSIIEKLKEISLEFLKKRESIKSFDDIISKSIKYIKEKPNGSYSAYLSAIMLFDEINDEASKITDILLKYYRIYIKIYIYIQKIFYNKNILEIKEKLVNEKEVQLKDIYLFIKSEDDIITLIKNNLEETKNIIKEEAFINSITENTKCTISFINAIFSDELRSLIDNKFDFVFKVLDTERDQRIQNHCILIIKNYGISIRSEVEKLAVEGKKSSIKIYQEIIKYWDLQKIDADFKFKNIDEIEEYVNKQYNKEHEILIKDIDENILSNILLKDKKTVSPLKIVKYVFMEYAALKEPSILKDCNKIAEFFDIDSFRNALNNIYTNWIKNKSNTEIKNIFIQYNNLTEDKLLQLPSETTNISYTTYDIKLKNILIPYCIFQTEDKLLQLKIQIEDWASSDMNDSEELAAYAVYAMALNGSSFALSLINKIYLEVKNKKVKKAAKNVLKKAGKVLDIL
>NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein
MDKEIEDFNKNFDDEILDIAFVLKKQNLSAGKSKGKYYTLLVSAIAYKNIITNEIIENENLLIVKEIEDTKHYFQIFRNKTIVRLKVRKEKDSSGLYMRFLLEDIIDTNYKDNDLNIILEKYSKPVYYKDEELGDFELDKSINMFNKNIEWDNNNISISFENIDEEVNKKSVDIIRKIFASKKDIDKKLKEYISENLIEDANTWNDDDDKPHISKEEFVKLITLTSITIIYENNITFYFDDGDIFSRHVIAVDSDYDFNFEDAHIEG
>NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein
MDKEIEDFNKDFDDEIFDMAFVLKRSCCKYNKIPWDKYYTLFVSAIALKNISANVIIENTHIIIHKKVKEPEEYLKILKDESIVKLKVRKEKDPDDFYIRFLLEDIIDTNYKDNDLNIILEKYSEIIYYKDEELGDFVLNKDINSFKKEMTWTESNISIFFDNIDEEFNKQSVDIIKKIFSNKKDIDSKLKECAAESIFKPHNMEREEFIKLISLESISIYSKNCITFYFDDIDGHTILVNSDWDFNFKPITELMFF
>NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein
MKTLYFIITLFLISCTNNSYKDIFSNRDINFKKLSLDNDILYQNKYDISDIKVKLMPLNNSVRLTDEDKNHIIKNTGYVKDLYHIESIFWEENTQTTCLVGYMKKDNNSLEKLINYINKMERDNNILKNYFYINGKKNIQYKIQLENTVLFYTIFEAKDSKYLVLSYTFPEKNEYASMYNIANSINSVEFY
>NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein
MVKMIILLSIISIFAVSCSYQHRHLVGNGPQTGVTLTRKQWYALWGLVPVNDVDVEKLAGGSENYEIYTRSNAGDFFINLFTGIIGFTSRTVTVRK
>NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein
MKQNKKTFLLSYLVFILAIILFIVIFSILGSVERVGYLSNFNHILENKYYFTLKFESSIFKNNKIYRVYPNTNEMPDNVTNIRWSGSYYGNLVLGDSSIQLKENDKIENIKYTVKIQKNVFLFLLFIIIVFPAIYFYVIPNIYYHHKSYIFFFVLNSLLYLITSNLIMPLFSMMKLDFNIYDFLYTYLFVMIAYNLLVHYPFNLGNIKNIRIILTALFCVVSIFSFFAIESISLTVLSMVILFSDMPNLYSSLITVLPMHLKIITITVSIIYFSSLLAFVILFIFNIYKIFVERNKIASLVMIAFIIFTVFYLFLKPKNIDIWSIDFVRNAKRNGIINTLNYRINYDRLNNIKPSKELVSDSIKLLKEYESKRDVSKLYLKSTKNIFDNIKKIEDDMHSILIEASSKNSNFVYNNENIDYEYIEQLKNNYYDVYTNFEISITNDLSKIEELKKGLKRDVYLIFLESFYDYSHFRKLFNKDPFPKEYRKWADSSRKIAPNVNNGSFYARLSGLTGSSPLYPKTQSEKIENTLPDILSKNGYNTIALEEALNTYNLKTFYPSIGFKSQLFGLGTTNINTYLGTNIDNLGSPVFAAGFTILGHTDSHLSNDLNFAENNKKFLDNFEGNDKLHIIETIDNSAMTAINIIEIRDTILKHSPNAIIIFKHDHLYPYLKAIIERSSIDEKIKTNFLNDYKPSPVLIWDGTNGAYKAPENFTPENIPLFIAANLNVDYTNSVISLLYKEEIDDTISTYNKFYHTTNDSLIDNSEVSNMMIFKYENAQRTLSQDIFQGKKHYYNFIK
>NC_017243.1|WP_014489113.1|3088548_3088962_-|hypothetical-protein
MKTLLKTISLTLMIIFLASCSNDITKTGSGIDSKYQGKYSGAINRKHQNGIEDGRATFTINNDGSVKGSVTYYGGSNPEDVELSKEIIIKNSDNSYSAEINFTGLKKYTFTFNNNMLELNIVNEDNSVTSGQLTESN
>NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase
MKALIITDNFFEDSELFYPYFRLVEEGIEVDIAALNKGEIKGEYFFKVEAKLDFSEVDPSNYKALIIPGGRAPEAIRGNENVKKIIKYFVDNNLTIGAICHGQQTLISAKVLEGKDATCYIGIRDDLMNAKANYKDEKVVVCGNIITSRCPDDLPYFAKEIIKKLK
>NC_017243.1|WP_014489115.1|3089654_3090560_-|hypothetical-protein
MKKAIIKIAVCFTAVLFAVSCGNDANTVTNPPIMDDTYDFKVYLSTVSTAPNYDRINVSSDKTKVSKASSLEFSMTPGIVKEAQARITDVKKDNASSLVLDISDFTIDSTITDLTESVLTLTQSGINKVKNANLTAATEYIYNVDITFTSDNEKLKNKEAVVTVPIKILVIKNVTKTDIENIIKKANGGTITISGGDASFDLNSFQLNQSGSTITSTGDNGGTYKAQEAAELFWKITDDNLKYSPSAKTSPISGDGKTADFTITLQFKDGYEIEDSNYAFVNKDGIKLSLKLNGTGNWKEY
>NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase
MNIKFDILKPFEKWANTEKRLKIAYGGRGGGKSESIARILIAKSFEKSGVILCSREIQKSISYSTYPLLISIIKELKLEKFFNIKRNEIINKITNCKFIFLGIRECSIEEIKSIYNVRICFIEEAQTLTQRSYEILEPSIRAEKSEIWIAFNPRFETDFIYQTVSKFNLENKFYTDKNNNKYNYQEYEDNNILITFINYDGNYYFSDILNKSRLSTLKLMPKMYDHIWLGKIKNKQGKIFLYSKLKFYDDNLKENINKINSSEHKAVVDPAFGEYNCFTSAIIYTQIGEDIYLIDSGLIRNDSNSTTDESIINFLSNKNIKKILCESNFAQKELVKRLEKHFEVTPFYVHKNKAERIVNASYLIYDKVYFPKSWQKVPEGSDTDKWLKTNNGRGYIALRQLLNFDDSLVGSSIKGDAFSYLDFPDALSSLIFFGIEEIINEENDDKMNLVNAIFGE
>NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase
MKFFIDTANVDEIKKANDMGVICGVTTNPSLIAKEGRDFKKTIEEITTIVDGPISGEVKATTVKAEDMIAEAREIAKIHKNMVVKIPMTDEGLKAVKVLAKEGIKTNVTLIFSANQALLAARAGATYVSPFIGRLDDISMDGLELIRTISEIFATHAIETEIISASVRHPIHVTECALAGADIATVPYSVILQMTKHPLTDQGIEKFKKDYEAVFGK
>NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase
MFDSLKDTFTLNNGYKIPCIGFGTWQTPDGETAVNSVIEAIKSGYKHIDTAAIYGNEKSIGKAIKESGINRNELFITSKVWNKDRGYKTTLAAFEKTINDLQIDYLDLYLIHWPASVNKFNDWDNINLETWRAMTELYKAGKIKSIGVSNFMPHHLKSLMETEVKPMVDQIEFHPGFMQEETFKYCNDNNILVEAWSPLGTGKMLDNETLKIVASKYNKSVAQICIRWCLQNNTLPLPKSVTASRIKENTEIFDFVISDEDMKTINAMEYCGGSGHHPDKVNF
>NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase
MNIVCLGDSTTYGYMVGRNKVWTKILNDKFHKENKNIKFINKGINGDMISGMLVRFDMDCIKENADTVILMGGVNDIFTCKPLEKIENNFINIINKALENNIDIIVFTPITFVKEAFSFFESNNIEEFENILKEYVNFINDYTSKNNIKSIDVYDLFTNKILKENNYYDIFFDGVHLSENGHSVFASEIYKELNKYL
>NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein
MKKSNENTSLKYLELAKEKEEIGEYKEALEYYEKSIEEDPDNIEAYFGLNLINSYIEMEKELKNDDASDNINKHIEFFNIFNEFLNKK
>NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter
MSNIDNIDNNVSNVSENKLLAIIALVLLSFALGTSEFIVIGVLTEIAEGFNITEVKAGGLVSMFALAYSICTPFSAAFAGKFNRFHFIIFASILFIAGNFLCSLASNYTFLLIIRMFIAIISGALISVSISFSPYISTKDKRPMVVAWIYSGFSIASIFGVPIGTSISYYFGWRASFIFISIFSAVMLVLMFATLPKNTPTHKVKLLGQFILFKDTRFILSTFTILFGAASSYVLYTYLKPIFLDYIHIPNKYISAALLVFGVTVLFSNLLSGKLAEHNGVYRLRYVFMMQFICMIVLPFALLNAISSSIVILIIGFLMYLMNSPVQLNILDFTEREYPSCLTLASSNNSFSFNFGIALGSFVGSTIFDNFGIRWVGFGGAVLSTLAFLCIVYLYKINSKTNNV
>NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin
MDLKNSKTAENLKTAFMGEAMARCKYMYYAEKAREDGMENLALAYEKASRNEQEHGKLWFERYHGILSKDENLRDAIAGETYESEDMYLKFAKTAKDEGFTDIAMLFEHVAKIEEGHKKMFEQYLDGSNTNLDKWQCPKCGYVHKDSKAPKRCPVCEQYRVGGSN

Crispr_ID: NC_017243_12

• CRISPR_ID: NC_017243_12
• CRISPR_location: 3088247-3088329
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017243_12

Consensus_repeat	Method
ATAATAATTATTTTGGTATGGAT	CRISPRCasFinder

spacers of NC_017243_12

>12.1|3088270|37|NC_017243|CRISPRCasFinder
TTGCAGGAATATTATTATTCTGATATGCATTATAATT

CRISPR arrays and Neighbor proteins around NC_017243_12

CRISPR arrays

The CRISPR arrays of NC_017243_12

>merge|NC_017243|12|3088247-3088329|CRISPRCasFinder
ATAATAATTATTATAGTAGTTATTTGCAGGAATATTATTATTCTGATATGCATTATAATTATTCTGATTATTTTGATAGTTAT

>NC_017243|12|12|3088247-3088329|CRISPRCasFinder
ATAATAATTATTATAGTAGTTAT	TTGCAGGAATATTATTATTCTGATATGCATTATAATT
ATTCTGATTATTTTGATAGTTAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase	unknown	unknown	gnl|CDD|234947
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	unknown	unknown	gnl|CDD|293739
NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase	unknown	unknown	gnl|CDD|335802
NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein	unknown	unknown	gnl|CDD|379270
NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin	unknown	unknown	gnl|CDD|153100
NC_017243.1|WP_014489107.1|3073758_3076242_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381297
NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|379179
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	unknown	unknown	gnl|CDD|368828
NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase	unknown	unknown	gnl|CDD|153228
NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase	unknown	unknown	gnl|CDD|239945
NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein	unknown	unknown	gnl|CDD|237177
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356
NC_017243.1|WP_014489115.1|3089654_3090560_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase	unknown	unknown	gnl|CDD|240363
NC_017243.1|WP_014489113.1|3088548_3088962_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase	gnl|CDD|234947	PRK01362, PRK01362, fructose-6-phosphate aldolase.	1.13091e-142
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	5.03223e-06
NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.45176e-67
NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase	gnl|CDD|335802	pfam04466, Terminase_3, Phage terminase large subunit. Initiation of packaging of double-stranded viral DNA involves the specific interaction of the prohead with viral DNA in a process mediated by a phage-encoded terminase protein. The terminase enzymes are usually hetero-oligomers composed of a small and a large subunit. This region is found on the large subunit and possess an endonuclease and ATPase activity that require Mg2+ and a neutral or slightly basic reaction. This region is also found in bacterial sequences.	1.47436e-22
NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein	gnl|CDD|379270	pfam13569, DUF4132, Domain of unknown function (DUF4132). This domain might be involved in the biosynthesis of the molybdopterin cofactor in E.coli.	3.74866e-57
NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	1.25265e-47
NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein	gnl|CDD|379179	pfam13428, TPR_14, Tetratricopeptide repeat.	3.83113e-05
NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase	gnl|CDD|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	6.73503e-139
NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.02463e-16
NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase	gnl|CDD|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	3.9814e-71
NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase	gnl|CDD|239945	cd04501, SGNH_hydrolase_like_4, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	8.80273e-40
NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	1.90547e-08
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.03733e-32
NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase	gnl|CDD|240363	PTZ00331, PTZ00331, alpha/beta hydrolase; Provisional.	1.40038e-05
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	gnl|CDD|368828	pfam06291, Lambda_Bor, Bor protein. This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the Escherichia coli host cell in animal serum. This property is a well known bacterial virulence determinant indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.	3.24795e-08

Protein sequences

>NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase
MSVKIPYEKIVNEDFIGKEVNPINQQDIYKIALEYSNEVIKEFEDESINLLIVDPQRDFIDMEKGALPVKGAVDDIKNIIRFIYDNMERLSSIYVTLDTHRYDSIFHSIMWNDFNDKPVAPFTEITLEKILNDEIIPVYDEEIQINYVKALKEKNAQNLMIWPYHCIYATDGWLIDKQLANILLFFETSRRVYINKILKGQDSFSEMYGVIRPEVPTEYTKNYDTSWVYDIANADKIYICGEAKDYCVYESVKQFCEIYHNDKSVTETINIMMNCSSAIGDNKACEQKYEELSSKYGIKLLNI
>NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA
MNKEEAKQKIEQLTETINYHNKLYYTDDNPEIEDYEYDKLFRELENLEREFPELKKDDSPTNKVGGTILEKFEKFEHPIAMYSLSNVMNEEEFLEFDNRMQKELNQSKIKYTVENKFDGLALELIYEKGKLTVASTRGDGQVGENVTNNVKMMNNVPKSIKEKKKLIVRGEALITKKDFEALNKEREELEEIPFANARNAASGGLRQLDSAESKKRRLKFFAYQIANYKDFDLTNEYKSMEFLSELGFTVEGVHPNIDAKKVLETYYDIQEKRSKMDYEIDGLVIKVDDVKHQEKLGFLSRAPRFAVAFKFKPEEKETVLKNIEVQVGRTGALTPVAKLEPVQVGGVTVSNVTLHNPNEIKSKDIRIGDTIVVIRSGDVIPKITRVVLEKRPADSKPFEFPKKCPVCGGDTAVTDGDVIVRCINEECPSKITRYIEYFVSKPAMNMERIGKEWIAVFTKSGLVKTPADLYKITRDDLFKFERMGEKLAGYMLESIENSKNTTLKRFIYALGIRQVGETTADLLAKYFTSIDNFKKATIDDLQNIEGIGEISAKSIYDFLHNEKTLKLIDDLLAAGVNPVFEKVVTVESPLTGKNVVITGSIEGFTRNSAKEAAERLGATVQSAVSKNTNILIVGEKAGSKLKKAQDLGVEIMEADKFIKLANG
>NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein
MSDNTNNLNNRNNTTFILYIVVCSIFLIALIIIYLLFSSSIKKSMDYSIGKFETNSQIQLSNYYEFLKEMVTNESFENKEFIKNTLEEAFKPNIDLLRETLKDSKDFSINTVTFWLAFLSLIMIIFTILGIYANNKIMESNQKQSELIIKDLESKAENSFNNIGELVKENKEYIENLKSDFDNIKNSLLSEMETIKDDAIKTKDNTLNEVNSIKKEIDSNKKESEDLKSEIYEIRDESKKLLKEMREERKAQSEEGKNIIEKIKIEGNTQKEEAKDLKSEIERIKEEAEKMLKEMKEEREVQKEESEQTLEELNKKAKEIESTLKKIEKQTKQSKINADRAKVSELFNRALRENDKNNKEKAIKLYTEIINEYNSNDTDSLNNRGVLYSDKYKETKDEEYFDKALEDYNHILRIDNNDYGTYINMSFLYLNHYEINKENKESLTQAEKYLNEGLKLYTNDLELINNYGILLYFKYKEDKKTVDLNNSEMYFNKSIGNTRTKENIGETYYYLHLVYDEYAKLDENISGYSKEECEKKSKEYLQKSKDLGYKHFMDK
>NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein
MENNISNEEQIRNKFERIFQYENNKNAFLDYFYGRSNSCPTLRNYYGYEAEDIFKFYFDENTKEEDKKALSRYAEAIIKDIYKNQNVHIILRLSTGEDLEKALIESYNNTYERTIYDKKYSKATLLNNEASKYIQIQVNNFYKFSELEAYVYKDFNQYLEKVKNDNKALLNKEPRLLLTILVYLINRDDDKSLIKQLLNYIDLLKINYEETISLLFTIVDKDEEVYKRLMNILNKDNNMIYFLVNIYKDMTRTIKLYKRLFKGYSEDKGYYYYTQKLIPEYLELCNFPKECILLNTIVNNNTLFISYLTVEAKKLYDEDKETFYKLYEIIEKSKLENLYLDYAMLSSIMLASGDNKYNIDTNSIVETLKTMCVELLKIMQPIQSFDEITSKSFKYVKEEPYTNHSHYLSAIMSFDGINDEASEITTKLLKHYGIYGKISIYVSIQKIFYNRNILEAKEKLVNDKKVPLKDIYLSLLDSKDNIITLIKNNVEETKSIMEEKSFITSITANISGTISFINCIFSDELSGLIDNKFDFVFKVLDTAKSKEIKKHCVSVISNNESIVRSKVEKLANEGKEASRTVYKEIIKYWDLQKFDDDFQFTSVDEINEYLNKYYNEGHESLIKDIDENILSNILLKDKKTKAPLKIVQYVFMEYVALKEPSILKDCNKIAEFFDIDSFRNALDNIYTNWLNNKADTKLKNILIPYCIFQPEDKLLKLKTQIEEWALNARGALAAHAVYAIALNASKFALVLVDTMSVKIKNNQVKNAAKDALKKTAKALEISEDELIDKIIPDLDFDKKGMRELHYGGEANRVFKLQIKNDFTIEVTDSNDKVLKSLPAPNSKDDKETADASKKELTLIKKNIKMITSNQITRLNKVLLNGRKWSYKTFTELFVENPIMNIFALKLIWGVYDEKNNLIESFRYMEDGSFNTFDEEEYIFEDSLKNKKNITLVHPIELDEEQLSKWKTQLSDYEISQPINQLDLLFEEVKEEHIKNNKIISFEDQEITAGEIMSMANKMSFERSRDIEDGGSYTYYELKDSILNIACRIDFEYMWFGIEANEKVTFKNIAFHRLDENGNCNAEEYINPLDINKRFTSSIYGTVKSYFMK
>NC_017243.1|WP_014489107.1|3073758_3076242_-|hypothetical-protein
MKNSISNEEKIRNKFEEMFSHENNKDAFLDYFYGKSNSCPTLSKNYLYYAEEIFKFYFDENTSKGDKEVLSRYAKVIIKDIYKGNPNPNYIIITTYMIVRLCSGEDLEKVLIESYNIDIEEIYIDDKKYSKSQLKNNKGYEYIKIQNKNFNRFLILENYIGKEFNEYLEKVKNDSKVLLEKEPHLLLTILVYIINRDDDKSLIKQLLNYIDLLKINDEETISLLFTIVDKDEEVYKRLINILNKDNNIIYFIVNLDSVMITNIELCKRFFKKYSEDPTYHYFEAREVADEYLEICSFPKEYIFLNKIYCGGNTHCTSSLTVELKKLYIEDKTTFYKLYEIIEKSKLECLYLDYVVLSAIMLAVNDNKYNINANSIIEKLKEISLEFLKKRESIKSFDDIISKSIKYIKEKPNGSYSAYLSAIMLFDEINDEASKITDILLKYYRIYIKIYIYIQKIFYNKNILEIKEKLVNEKEVQLKDIYLFIKSEDDIITLIKNNLEETKNIIKEEAFINSITENTKCTISFINAIFSDELRSLIDNKFDFVFKVLDTERDQRIQNHCILIIKNYGISIRSEVEKLAVEGKKSSIKIYQEIIKYWDLQKIDADFKFKNIDEIEEYVNKQYNKEHEILIKDIDENILSNILLKDKKTVSPLKIVKYVFMEYAALKEPSILKDCNKIAEFFDIDSFRNALNNIYTNWIKNKSNTEIKNIFIQYNNLTEDKLLQLPSETTNISYTTYDIKLKNILIPYCIFQTEDKLLQLKIQIEDWASSDMNDSEELAAYAVYAMALNGSSFALSLINKIYLEVKNKKVKKAAKNVLKKAGKVLDIL
>NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein
MDKEIEDFNKNFDDEILDIAFVLKKQNLSAGKSKGKYYTLLVSAIAYKNIITNEIIENENLLIVKEIEDTKHYFQIFRNKTIVRLKVRKEKDSSGLYMRFLLEDIIDTNYKDNDLNIILEKYSKPVYYKDEELGDFELDKSINMFNKNIEWDNNNISISFENIDEEVNKKSVDIIRKIFASKKDIDKKLKEYISENLIEDANTWNDDDDKPHISKEEFVKLITLTSITIIYENNITFYFDDGDIFSRHVIAVDSDYDFNFEDAHIEG
>NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein
MDKEIEDFNKDFDDEIFDMAFVLKRSCCKYNKIPWDKYYTLFVSAIALKNISANVIIENTHIIIHKKVKEPEEYLKILKDESIVKLKVRKEKDPDDFYIRFLLEDIIDTNYKDNDLNIILEKYSEIIYYKDEELGDFVLNKDINSFKKEMTWTESNISIFFDNIDEEFNKQSVDIIKKIFSNKKDIDSKLKECAAESIFKPHNMEREEFIKLISLESISIYSKNCITFYFDDIDGHTILVNSDWDFNFKPITELMFF
>NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein
MKTLYFIITLFLISCTNNSYKDIFSNRDINFKKLSLDNDILYQNKYDISDIKVKLMPLNNSVRLTDEDKNHIIKNTGYVKDLYHIESIFWEENTQTTCLVGYMKKDNNSLEKLINYINKMERDNNILKNYFYINGKKNIQYKIQLENTVLFYTIFEAKDSKYLVLSYTFPEKNEYASMYNIANSINSVEFY
>NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein
MVKMIILLSIISIFAVSCSYQHRHLVGNGPQTGVTLTRKQWYALWGLVPVNDVDVEKLAGGSENYEIYTRSNAGDFFINLFTGIIGFTSRTVTVRK
>NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein
MKQNKKTFLLSYLVFILAIILFIVIFSILGSVERVGYLSNFNHILENKYYFTLKFESSIFKNNKIYRVYPNTNEMPDNVTNIRWSGSYYGNLVLGDSSIQLKENDKIENIKYTVKIQKNVFLFLLFIIIVFPAIYFYVIPNIYYHHKSYIFFFVLNSLLYLITSNLIMPLFSMMKLDFNIYDFLYTYLFVMIAYNLLVHYPFNLGNIKNIRIILTALFCVVSIFSFFAIESISLTVLSMVILFSDMPNLYSSLITVLPMHLKIITITVSIIYFSSLLAFVILFIFNIYKIFVERNKIASLVMIAFIIFTVFYLFLKPKNIDIWSIDFVRNAKRNGIINTLNYRINYDRLNNIKPSKELVSDSIKLLKEYESKRDVSKLYLKSTKNIFDNIKKIEDDMHSILIEASSKNSNFVYNNENIDYEYIEQLKNNYYDVYTNFEISITNDLSKIEELKKGLKRDVYLIFLESFYDYSHFRKLFNKDPFPKEYRKWADSSRKIAPNVNNGSFYARLSGLTGSSPLYPKTQSEKIENTLPDILSKNGYNTIALEEALNTYNLKTFYPSIGFKSQLFGLGTTNINTYLGTNIDNLGSPVFAAGFTILGHTDSHLSNDLNFAENNKKFLDNFEGNDKLHIIETIDNSAMTAINIIEIRDTILKHSPNAIIIFKHDHLYPYLKAIIERSSIDEKIKTNFLNDYKPSPVLIWDGTNGAYKAPENFTPENIPLFIAANLNVDYTNSVISLLYKEEIDDTISTYNKFYHTTNDSLIDNSEVSNMMIFKYENAQRTLSQDIFQGKKHYYNFIK
>NC_017243.1|WP_014489113.1|3088548_3088962_-|hypothetical-protein
MKTLLKTISLTLMIIFLASCSNDITKTGSGIDSKYQGKYSGAINRKHQNGIEDGRATFTINNDGSVKGSVTYYGGSNPEDVELSKEIIIKNSDNSYSAEINFTGLKKYTFTFNNNMLELNIVNEDNSVTSGQLTESN
>NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase
MKALIITDNFFEDSELFYPYFRLVEEGIEVDIAALNKGEIKGEYFFKVEAKLDFSEVDPSNYKALIIPGGRAPEAIRGNENVKKIIKYFVDNNLTIGAICHGQQTLISAKVLEGKDATCYIGIRDDLMNAKANYKDEKVVVCGNIITSRCPDDLPYFAKEIIKKLK
>NC_017243.1|WP_014489115.1|3089654_3090560_-|hypothetical-protein
MKKAIIKIAVCFTAVLFAVSCGNDANTVTNPPIMDDTYDFKVYLSTVSTAPNYDRINVSSDKTKVSKASSLEFSMTPGIVKEAQARITDVKKDNASSLVLDISDFTIDSTITDLTESVLTLTQSGINKVKNANLTAATEYIYNVDITFTSDNEKLKNKEAVVTVPIKILVIKNVTKTDIENIIKKANGGTITISGGDASFDLNSFQLNQSGSTITSTGDNGGTYKAQEAAELFWKITDDNLKYSPSAKTSPISGDGKTADFTITLQFKDGYEIEDSNYAFVNKDGIKLSLKLNGTGNWKEY
>NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase
MNIKFDILKPFEKWANTEKRLKIAYGGRGGGKSESIARILIAKSFEKSGVILCSREIQKSISYSTYPLLISIIKELKLEKFFNIKRNEIINKITNCKFIFLGIRECSIEEIKSIYNVRICFIEEAQTLTQRSYEILEPSIRAEKSEIWIAFNPRFETDFIYQTVSKFNLENKFYTDKNNNKYNYQEYEDNNILITFINYDGNYYFSDILNKSRLSTLKLMPKMYDHIWLGKIKNKQGKIFLYSKLKFYDDNLKENINKINSSEHKAVVDPAFGEYNCFTSAIIYTQIGEDIYLIDSGLIRNDSNSTTDESIINFLSNKNIKKILCESNFAQKELVKRLEKHFEVTPFYVHKNKAERIVNASYLIYDKVYFPKSWQKVPEGSDTDKWLKTNNGRGYIALRQLLNFDDSLVGSSIKGDAFSYLDFPDALSSLIFFGIEEIINEENDDKMNLVNAIFGE
>NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase
MKFFIDTANVDEIKKANDMGVICGVTTNPSLIAKEGRDFKKTIEEITTIVDGPISGEVKATTVKAEDMIAEAREIAKIHKNMVVKIPMTDEGLKAVKVLAKEGIKTNVTLIFSANQALLAARAGATYVSPFIGRLDDISMDGLELIRTISEIFATHAIETEIISASVRHPIHVTECALAGADIATVPYSVILQMTKHPLTDQGIEKFKKDYEAVFGK
>NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase
MFDSLKDTFTLNNGYKIPCIGFGTWQTPDGETAVNSVIEAIKSGYKHIDTAAIYGNEKSIGKAIKESGINRNELFITSKVWNKDRGYKTTLAAFEKTINDLQIDYLDLYLIHWPASVNKFNDWDNINLETWRAMTELYKAGKIKSIGVSNFMPHHLKSLMETEVKPMVDQIEFHPGFMQEETFKYCNDNNILVEAWSPLGTGKMLDNETLKIVASKYNKSVAQICIRWCLQNNTLPLPKSVTASRIKENTEIFDFVISDEDMKTINAMEYCGGSGHHPDKVNF
>NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase
MNIVCLGDSTTYGYMVGRNKVWTKILNDKFHKENKNIKFINKGINGDMISGMLVRFDMDCIKENADTVILMGGVNDIFTCKPLEKIENNFINIINKALENNIDIIVFTPITFVKEAFSFFESNNIEEFENILKEYVNFINDYTSKNNIKSIDVYDLFTNKILKENNYYDIFFDGVHLSENGHSVFASEIYKELNKYL
>NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein
MKKSNENTSLKYLELAKEKEEIGEYKEALEYYEKSIEEDPDNIEAYFGLNLINSYIEMEKELKNDDASDNINKHIEFFNIFNEFLNKK
>NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter
MSNIDNIDNNVSNVSENKLLAIIALVLLSFALGTSEFIVIGVLTEIAEGFNITEVKAGGLVSMFALAYSICTPFSAAFAGKFNRFHFIIFASILFIAGNFLCSLASNYTFLLIIRMFIAIISGALISVSISFSPYISTKDKRPMVVAWIYSGFSIASIFGVPIGTSISYYFGWRASFIFISIFSAVMLVLMFATLPKNTPTHKVKLLGQFILFKDTRFILSTFTILFGAASSYVLYTYLKPIFLDYIHIPNKYISAALLVFGVTVLFSNLLSGKLAEHNGVYRLRYVFMMQFICMIVLPFALLNAISSSIVILIIGFLMYLMNSPVQLNILDFTEREYPSCLTLASSNNSFSFNFGIALGSFVGSTIFDNFGIRWVGFGGAVLSTLAFLCIVYLYKINSKTNNV
>NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin
MDLKNSKTAENLKTAFMGEAMARCKYMYYAEKAREDGMENLALAYEKASRNEQEHGKLWFERYHGILSKDENLRDAIAGETYESEDMYLKFAKTAKDEGFTDIAMLFEHVAKIEEGHKKMFEQYLDGSNTNLDKWQCPKCGYVHKDSKAPKRCPVCEQYRVGGSN

Crispr_ID: NC_017243_10

• CRISPR_ID: NC_017243_10
• CRISPR_location: 3087665-3087781
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017243_10

Consensus_repeat	Method
ATAATAATTATTTTGGTATGGAT	CRISPRCasFinder

spacers of NC_017243_10

>10.1|3087688|25|NC_017243|CRISPRCasFinder
CCTGTGCAGTATTGTCATAAGCACT
>10.2|3087736|22|NC_017243|CRISPRCasFinder
TATCATAAGCATTATAGTCATT

CRISPR arrays and Neighbor proteins around NC_017243_10

CRISPR arrays

The CRISPR arrays of NC_017243_10

>merge|NC_017243|10|3087665-3087781|CRISPRCasFinder
ATAATATCCGTTTTGATACTGATCCTGTGCAGTATTGTCATAAGCACTATAATAATTATTTTGATAAGTATTATCATAAGCATTATAGTCATTATAATAATTATTTTGTGCAGTACC

>NC_017243|10|10|3087665-3087781|CRISPRCasFinder
ATAATATCCGTTTTGATACTGAT	CCTGTGCAGTATTGTCATAAGCACT
ATAATAATTATTTTGATAAGTAT	TATCATAAGCATTATAGTCATT
ATAATAATTATTTTGTGCAGTACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase	unknown	unknown	gnl|CDD|234947
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	unknown	unknown	gnl|CDD|293739
NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase	unknown	unknown	gnl|CDD|335802
NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein	unknown	unknown	gnl|CDD|379270
NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin	unknown	unknown	gnl|CDD|153100
NC_017243.1|WP_014489107.1|3073758_3076242_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381297
NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl|CDD|236137
NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|379179
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	unknown	unknown	gnl|CDD|368828
NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase	unknown	unknown	gnl|CDD|153228
NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase	unknown	unknown	gnl|CDD|239945
NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein	unknown	unknown	gnl|CDD|237177
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356
NC_017243.1|WP_014489115.1|3089654_3090560_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase	unknown	unknown	gnl|CDD|240363
NC_017243.1|WP_014489113.1|3088548_3088962_-|hypothetical-protein	unknown	unknown	unknown
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	unknown	unknown	gnl|CDD|378356

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase	gnl|CDD|234947	PRK01362, PRK01362, fructose-6-phosphate aldolase.	1.13091e-142
NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	5.03223e-06
NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.45176e-67
NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase	gnl|CDD|335802	pfam04466, Terminase_3, Phage terminase large subunit. Initiation of packaging of double-stranded viral DNA involves the specific interaction of the prohead with viral DNA in a process mediated by a phage-encoded terminase protein. The terminase enzymes are usually hetero-oligomers composed of a small and a large subunit. This region is found on the large subunit and possess an endonuclease and ATPase activity that require Mg2+ and a neutral or slightly basic reaction. This region is also found in bacterial sequences.	1.47436e-22
NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein	gnl|CDD|379270	pfam13569, DUF4132, Domain of unknown function (DUF4132). This domain might be involved in the biosynthesis of the molybdopterin cofactor in E.coli.	3.74866e-57
NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	1.25265e-47
NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein	gnl|CDD|379179	pfam13428, TPR_14, Tetratricopeptide repeat.	3.83113e-05
NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase	gnl|CDD|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	6.73503e-139
NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.02463e-16
NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase	gnl|CDD|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	3.9814e-71
NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase	gnl|CDD|239945	cd04501, SGNH_hydrolase_like_4, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	8.80273e-40
NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	1.90547e-08
NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein	gnl|CDD|378356	pfam10020, DUF2262, Uncharacterized protein conserved in bacteria (DUF2262). This domain, found in various hypothetical bacterial proteins, has no known function.	1.03733e-32
NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase	gnl|CDD|240363	PTZ00331, PTZ00331, alpha/beta hydrolase; Provisional.	1.40038e-05
NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein	gnl|CDD|368828	pfam06291, Lambda_Bor, Bor protein. This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the Escherichia coli host cell in animal serum. This property is a well known bacterial virulence determinant indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.	3.24795e-08

Protein sequences

>NC_017243.1|WP_014489111.1|3085883_3086795_-|nicotinamidase
MSVKIPYEKIVNEDFIGKEVNPINQQDIYKIALEYSNEVIKEFEDESINLLIVDPQRDFIDMEKGALPVKGAVDDIKNIIRFIYDNMERLSSIYVTLDTHRYDSIFHSIMWNDFNDKPVAPFTEITLEKILNDEIIPVYDEEIQINYVKALKEKNAQNLMIWPYHCIYATDGWLIDKQLANILLFFETSRRVYINKILKGQDSFSEMYGVIRPEVPTEYTKNYDTSWVYDIANADKIYICGEAKDYCVYESVKQFCEIYHNDKSVTETINIMMNCSSAIGDNKACEQKYEELSSKYGIKLLNI
>NC_017243.1|WP_014489110.1|3083090_3085082_+|NAD-dependent-DNA-ligase-LigA
MNKEEAKQKIEQLTETINYHNKLYYTDDNPEIEDYEYDKLFRELENLEREFPELKKDDSPTNKVGGTILEKFEKFEHPIAMYSLSNVMNEEEFLEFDNRMQKELNQSKIKYTVENKFDGLALELIYEKGKLTVASTRGDGQVGENVTNNVKMMNNVPKSIKEKKKLIVRGEALITKKDFEALNKEREELEEIPFANARNAASGGLRQLDSAESKKRRLKFFAYQIANYKDFDLTNEYKSMEFLSELGFTVEGVHPNIDAKKVLETYYDIQEKRSKMDYEIDGLVIKVDDVKHQEKLGFLSRAPRFAVAFKFKPEEKETVLKNIEVQVGRTGALTPVAKLEPVQVGGVTVSNVTLHNPNEIKSKDIRIGDTIVVIRSGDVIPKITRVVLEKRPADSKPFEFPKKCPVCGGDTAVTDGDVIVRCINEECPSKITRYIEYFVSKPAMNMERIGKEWIAVFTKSGLVKTPADLYKITRDDLFKFERMGEKLAGYMLESIENSKNTTLKRFIYALGIRQVGETTADLLAKYFTSIDNFKKATIDDLQNIEGIGEISAKSIYDFLHNEKTLKLIDDLLAAGVNPVFEKVVTVESPLTGKNVVITGSIEGFTRNSAKEAAERLGATVQSAVSKNTNILIVGEKAGSKLKKAQDLGVEIMEADKFIKLANG
>NC_017243.1|WP_014489109.1|3080425_3082093_-|hypothetical-protein
MSDNTNNLNNRNNTTFILYIVVCSIFLIALIIIYLLFSSSIKKSMDYSIGKFETNSQIQLSNYYEFLKEMVTNESFENKEFIKNTLEEAFKPNIDLLRETLKDSKDFSINTVTFWLAFLSLIMIIFTILGIYANNKIMESNQKQSELIIKDLESKAENSFNNIGELVKENKEYIENLKSDFDNIKNSLLSEMETIKDDAIKTKDNTLNEVNSIKKEIDSNKKESEDLKSEIYEIRDESKKLLKEMREERKAQSEEGKNIIEKIKIEGNTQKEEAKDLKSEIERIKEEAEKMLKEMKEEREVQKEESEQTLEELNKKAKEIESTLKKIEKQTKQSKINADRAKVSELFNRALRENDKNNKEKAIKLYTEIINEYNSNDTDSLNNRGVLYSDKYKETKDEEYFDKALEDYNHILRIDNNDYGTYINMSFLYLNHYEINKENKESLTQAEKYLNEGLKLYTNDLELINNYGILLYFKYKEDKKTVDLNNSEMYFNKSIGNTRTKENIGETYYYLHLVYDEYAKLDENISGYSKEECEKKSKEYLQKSKDLGYKHFMDK
>NC_017243.1|WP_014489108.1|3076900_3080227_-|DUF4132-domain-containing-protein
MENNISNEEQIRNKFERIFQYENNKNAFLDYFYGRSNSCPTLRNYYGYEAEDIFKFYFDENTKEEDKKALSRYAEAIIKDIYKNQNVHIILRLSTGEDLEKALIESYNNTYERTIYDKKYSKATLLNNEASKYIQIQVNNFYKFSELEAYVYKDFNQYLEKVKNDNKALLNKEPRLLLTILVYLINRDDDKSLIKQLLNYIDLLKINYEETISLLFTIVDKDEEVYKRLMNILNKDNNMIYFLVNIYKDMTRTIKLYKRLFKGYSEDKGYYYYTQKLIPEYLELCNFPKECILLNTIVNNNTLFISYLTVEAKKLYDEDKETFYKLYEIIEKSKLENLYLDYAMLSSIMLASGDNKYNIDTNSIVETLKTMCVELLKIMQPIQSFDEITSKSFKYVKEEPYTNHSHYLSAIMSFDGINDEASEITTKLLKHYGIYGKISIYVSIQKIFYNRNILEAKEKLVNDKKVPLKDIYLSLLDSKDNIITLIKNNVEETKSIMEEKSFITSITANISGTISFINCIFSDELSGLIDNKFDFVFKVLDTAKSKEIKKHCVSVISNNESIVRSKVEKLANEGKEASRTVYKEIIKYWDLQKFDDDFQFTSVDEINEYLNKYYNEGHESLIKDIDENILSNILLKDKKTKAPLKIVQYVFMEYVALKEPSILKDCNKIAEFFDIDSFRNALDNIYTNWLNNKADTKLKNILIPYCIFQPEDKLLKLKTQIEEWALNARGALAAHAVYAIALNASKFALVLVDTMSVKIKNNQVKNAAKDALKKTAKALEISEDELIDKIIPDLDFDKKGMRELHYGGEANRVFKLQIKNDFTIEVTDSNDKVLKSLPAPNSKDDKETADASKKELTLIKKNIKMITSNQITRLNKVLLNGRKWSYKTFTELFVENPIMNIFALKLIWGVYDEKNNLIESFRYMEDGSFNTFDEEEYIFEDSLKNKKNITLVHPIELDEEQLSKWKTQLSDYEISQPINQLDLLFEEVKEEHIKNNKIISFEDQEITAGEIMSMANKMSFERSRDIEDGGSYTYYELKDSILNIACRIDFEYMWFGIEANEKVTFKNIAFHRLDENGNCNAEEYINPLDINKRFTSSIYGTVKSYFMK
>NC_017243.1|WP_014489107.1|3073758_3076242_-|hypothetical-protein
MKNSISNEEKIRNKFEEMFSHENNKDAFLDYFYGKSNSCPTLSKNYLYYAEEIFKFYFDENTSKGDKEVLSRYAKVIIKDIYKGNPNPNYIIITTYMIVRLCSGEDLEKVLIESYNIDIEEIYIDDKKYSKSQLKNNKGYEYIKIQNKNFNRFLILENYIGKEFNEYLEKVKNDSKVLLEKEPHLLLTILVYIINRDDDKSLIKQLLNYIDLLKINDEETISLLFTIVDKDEEVYKRLINILNKDNNIIYFIVNLDSVMITNIELCKRFFKKYSEDPTYHYFEAREVADEYLEICSFPKEYIFLNKIYCGGNTHCTSSLTVELKKLYIEDKTTFYKLYEIIEKSKLECLYLDYVVLSAIMLAVNDNKYNINANSIIEKLKEISLEFLKKRESIKSFDDIISKSIKYIKEKPNGSYSAYLSAIMLFDEINDEASKITDILLKYYRIYIKIYIYIQKIFYNKNILEIKEKLVNEKEVQLKDIYLFIKSEDDIITLIKNNLEETKNIIKEEAFINSITENTKCTISFINAIFSDELRSLIDNKFDFVFKVLDTERDQRIQNHCILIIKNYGISIRSEVEKLAVEGKKSSIKIYQEIIKYWDLQKIDADFKFKNIDEIEEYVNKQYNKEHEILIKDIDENILSNILLKDKKTVSPLKIVKYVFMEYAALKEPSILKDCNKIAEFFDIDSFRNALNNIYTNWIKNKSNTEIKNIFIQYNNLTEDKLLQLPSETTNISYTTYDIKLKNILIPYCIFQTEDKLLQLKIQIEDWASSDMNDSEELAAYAVYAMALNGSSFALSLINKIYLEVKNKKVKKAAKNVLKKAGKVLDIL
>NC_017243.1|WP_014489106.1|3072927_3073731_-|DUF2262-domain-containing-protein
MDKEIEDFNKNFDDEILDIAFVLKKQNLSAGKSKGKYYTLLVSAIAYKNIITNEIIENENLLIVKEIEDTKHYFQIFRNKTIVRLKVRKEKDSSGLYMRFLLEDIIDTNYKDNDLNIILEKYSKPVYYKDEELGDFELDKSINMFNKNIEWDNNNISISFENIDEEVNKKSVDIIRKIFASKKDIDKKLKEYISENLIEDANTWNDDDDKPHISKEEFVKLITLTSITIIYENNITFYFDDGDIFSRHVIAVDSDYDFNFEDAHIEG
>NC_017243.1|WP_014489105.1|3071960_3072734_-|DUF2262-domain-containing-protein
MDKEIEDFNKDFDDEIFDMAFVLKRSCCKYNKIPWDKYYTLFVSAIALKNISANVIIENTHIIIHKKVKEPEEYLKILKDESIVKLKVRKEKDPDDFYIRFLLEDIIDTNYKDNDLNIILEKYSEIIYYKDEELGDFVLNKDINSFKKEMTWTESNISIFFDNIDEEFNKQSVDIIKKIFSNKKDIDSKLKECAAESIFKPHNMEREEFIKLISLESISIYSKNCITFYFDDIDGHTILVNSDWDFNFKPITELMFF
>NC_017243.1|WP_014489104.1|3070596_3071172_+|hypothetical-protein
MKTLYFIITLFLISCTNNSYKDIFSNRDINFKKLSLDNDILYQNKYDISDIKVKLMPLNNSVRLTDEDKNHIIKNTGYVKDLYHIESIFWEENTQTTCLVGYMKKDNNSLEKLINYINKMERDNNILKNYFYINGKKNIQYKIQLENTVLFYTIFEAKDSKYLVLSYTFPEKNEYASMYNIANSINSVEFY
>NC_017243.1|WP_014489103.1|3070284_3070575_+|hypothetical-protein
MVKMIILLSIISIFAVSCSYQHRHLVGNGPQTGVTLTRKQWYALWGLVPVNDVDVEKLAGGSENYEIYTRSNAGDFFINLFTGIIGFTSRTVTVRK
>NC_017243.1|WP_014489102.1|3067612_3070009_-|hypothetical-protein
MKQNKKTFLLSYLVFILAIILFIVIFSILGSVERVGYLSNFNHILENKYYFTLKFESSIFKNNKIYRVYPNTNEMPDNVTNIRWSGSYYGNLVLGDSSIQLKENDKIENIKYTVKIQKNVFLFLLFIIIVFPAIYFYVIPNIYYHHKSYIFFFVLNSLLYLITSNLIMPLFSMMKLDFNIYDFLYTYLFVMIAYNLLVHYPFNLGNIKNIRIILTALFCVVSIFSFFAIESISLTVLSMVILFSDMPNLYSSLITVLPMHLKIITITVSIIYFSSLLAFVILFIFNIYKIFVERNKIASLVMIAFIIFTVFYLFLKPKNIDIWSIDFVRNAKRNGIINTLNYRINYDRLNNIKPSKELVSDSIKLLKEYESKRDVSKLYLKSTKNIFDNIKKIEDDMHSILIEASSKNSNFVYNNENIDYEYIEQLKNNYYDVYTNFEISITNDLSKIEELKKGLKRDVYLIFLESFYDYSHFRKLFNKDPFPKEYRKWADSSRKIAPNVNNGSFYARLSGLTGSSPLYPKTQSEKIENTLPDILSKNGYNTIALEEALNTYNLKTFYPSIGFKSQLFGLGTTNINTYLGTNIDNLGSPVFAAGFTILGHTDSHLSNDLNFAENNKKFLDNFEGNDKLHIIETIDNSAMTAINIIEIRDTILKHSPNAIIIFKHDHLYPYLKAIIERSSIDEKIKTNFLNDYKPSPVLIWDGTNGAYKAPENFTPENIPLFIAANLNVDYTNSVISLLYKEEIDDTISTYNKFYHTTNDSLIDNSEVSNMMIFKYENAQRTLSQDIFQGKKHYYNFIK
>NC_017243.1|WP_014489113.1|3088548_3088962_-|hypothetical-protein
MKTLLKTISLTLMIIFLASCSNDITKTGSGIDSKYQGKYSGAINRKHQNGIEDGRATFTINNDGSVKGSVTYYGGSNPEDVELSKEIIIKNSDNSYSAEINFTGLKKYTFTFNNNMLELNIVNEDNSVTSGQLTESN
>NC_017243.1|WP_014489114.1|3089076_3089577_+|type-1-glutamine-amidotransferase
MKALIITDNFFEDSELFYPYFRLVEEGIEVDIAALNKGEIKGEYFFKVEAKLDFSEVDPSNYKALIIPGGRAPEAIRGNENVKKIIKYFVDNNLTIGAICHGQQTLISAKVLEGKDATCYIGIRDDLMNAKANYKDEKVVVCGNIITSRCPDDLPYFAKEIIKKLK
>NC_017243.1|WP_014489115.1|3089654_3090560_-|hypothetical-protein
MKKAIIKIAVCFTAVLFAVSCGNDANTVTNPPIMDDTYDFKVYLSTVSTAPNYDRINVSSDKTKVSKASSLEFSMTPGIVKEAQARITDVKKDNASSLVLDISDFTIDSTITDLTESVLTLTQSGINKVKNANLTAATEYIYNVDITFTSDNEKLKNKEAVVTVPIKILVIKNVTKTDIENIIKKANGGTITISGGDASFDLNSFQLNQSGSTITSTGDNGGTYKAQEAAELFWKITDDNLKYSPSAKTSPISGDGKTADFTITLQFKDGYEIEDSNYAFVNKDGIKLSLKLNGTGNWKEY
>NC_017243.1|WP_014489117.1|3093392_3094763_+|terminase
MNIKFDILKPFEKWANTEKRLKIAYGGRGGGKSESIARILIAKSFEKSGVILCSREIQKSISYSTYPLLISIIKELKLEKFFNIKRNEIINKITNCKFIFLGIRECSIEEIKSIYNVRICFIEEAQTLTQRSYEILEPSIRAEKSEIWIAFNPRFETDFIYQTVSKFNLENKFYTDKNNNKYNYQEYEDNNILITFINYDGNYYFSDILNKSRLSTLKLMPKMYDHIWLGKIKNKQGKIFLYSKLKFYDDNLKENINKINSSEHKAVVDPAFGEYNCFTSAIIYTQIGEDIYLIDSGLIRNDSNSTTDESIINFLSNKNIKKILCESNFAQKELVKRLEKHFEVTPFYVHKNKAERIVNASYLIYDKVYFPKSWQKVPEGSDTDKWLKTNNGRGYIALRQLLNFDDSLVGSSIKGDAFSYLDFPDALSSLIFFGIEEIINEENDDKMNLVNAIFGE
>NC_017243.1|WP_014489118.1|3095412_3096066_-|fructose-6-phosphate-aldolase
MKFFIDTANVDEIKKANDMGVICGVTTNPSLIAKEGRDFKKTIEEITTIVDGPISGEVKATTVKAEDMIAEAREIAKIHKNMVVKIPMTDEGLKAVKVLAKEGIKTNVTLIFSANQALLAARAGATYVSPFIGRLDDISMDGLELIRTISEIFATHAIETEIISASVRHPIHVTECALAGADIATVPYSVILQMTKHPLTDQGIEKFKKDYEAVFGK
>NC_017243.1|WP_014489119.1|3096150_3097002_-|aldo/keto-reductase
MFDSLKDTFTLNNGYKIPCIGFGTWQTPDGETAVNSVIEAIKSGYKHIDTAAIYGNEKSIGKAIKESGINRNELFITSKVWNKDRGYKTTLAAFEKTINDLQIDYLDLYLIHWPASVNKFNDWDNINLETWRAMTELYKAGKIKSIGVSNFMPHHLKSLMETEVKPMVDQIEFHPGFMQEETFKYCNDNNILVEAWSPLGTGKMLDNETLKIVASKYNKSVAQICIRWCLQNNTLPLPKSVTASRIKENTEIFDFVISDEDMKTINAMEYCGGSGHHPDKVNF
>NC_017243.1|WP_014489120.1|3097136_3097730_+|arylesterase
MNIVCLGDSTTYGYMVGRNKVWTKILNDKFHKENKNIKFINKGINGDMISGMLVRFDMDCIKENADTVILMGGVNDIFTCKPLEKIENNFINIINKALENNIDIIVFTPITFVKEAFSFFESNNIEEFENILKEYVNFINDYTSKNNIKSIDVYDLFTNKILKENNYYDIFFDGVHLSENGHSVFASEIYKELNKYL
>NC_017243.1|WP_014489121.1|3097733_3098000_-|tetratricopeptide-repeat-protein
MKKSNENTSLKYLELAKEKEEIGEYKEALEYYEKSIEEDPDNIEAYFGLNLINSYIEMEKELKNDDASDNINKHIEFFNIFNEFLNKK
>NC_017243.1|WP_014489122.1|3098119_3099334_+|MFS-transporter
MSNIDNIDNNVSNVSENKLLAIIALVLLSFALGTSEFIVIGVLTEIAEGFNITEVKAGGLVSMFALAYSICTPFSAAFAGKFNRFHFIIFASILFIAGNFLCSLASNYTFLLIIRMFIAIISGALISVSISFSPYISTKDKRPMVVAWIYSGFSIASIFGVPIGTSISYYFGWRASFIFISIFSAVMLVLMFATLPKNTPTHKVKLLGQFILFKDTRFILSTFTILFGAASSYVLYTYLKPIFLDYIHIPNKYISAALLVFGVTVLFSNLLSGKLAEHNGVYRLRYVFMMQFICMIVLPFALLNAISSSIVILIIGFLMYLMNSPVQLNILDFTEREYPSCLTLASSNNSFSFNFGIALGSFVGSTIFDNFGIRWVGFGGAVLSTLAFLCIVYLYKINSKTNNV
>NC_017243.1|WP_014489123.1|3099632_3100130_+|rubrerythrin
MDLKNSKTAENLKTAFMGEAMARCKYMYYAEKAREDGMENLALAYEKASRNEQEHGKLWFERYHGILSKDENLRDAIAGETYESEDMYLKFAKTAKDEGFTDIAMLFEHVAKIEEGHKKMFEQYLDGSNTNLDKWQCPKCGYVHKDSKAPKRCPVCEQYRVGGSN

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017243_3	3.2|317130|32|NC_017243|PILER-CR	317130-317161	32	NC_017243.1	316928-316959	0	1.0
NC_017243_3	3.3|317097|48|NC_017243|CRISPRCasFinder	317097-317144	48	NC_017243.1	316928-316975	0	1.0

1. spacer 3.2|317130|32|NC_017243|PILER-CR matches to position: 316928-316959, mismatch: 0, identity: 1.0

attcgcttctaggctattttaagtaaacttaa	CRISPR spacer
attcgcttctaggctattttaagtaaacttaa	Protospacer
********************************

2. spacer 3.3|317097|48|NC_017243|CRISPRCasFinder matches to position: 316928-316975, mismatch: 0, identity: 1.0

attcgcttctaggctattttaagtaaacttaaaataggctcataattt	CRISPR spacer
attcgcttctaggctattttaagtaaacttaaaataggctcataattt	Protospacer
************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017243_7	7.1|1633311|35|NC_017243|CRISPRCasFinder	1633311-1633345	35	NZ_CP033461	Brevibacillus laterosporus strain 1821L plasmid p1821L01, complete sequence	127776-127810	9	0.743
NC_017243_7	7.1|1633311|35|NC_017243|CRISPRCasFinder	1633311-1633345	35	NZ_AP018283	Chondrocystis sp. NIES-4102 plasmid plasmid2 DNA, complete genome	77502-77536	10	0.714

1. spacer 7.1|1633311|35|NC_017243|CRISPRCasFinder matches to NZ_CP033461 (Brevibacillus laterosporus strain 1821L plasmid p1821L01, complete sequence) position: , mismatch: 9, identity: 0.743

ctttgaagagtttaaaaataaaataactgaagaaa	CRISPR spacer
gagagagaagtttaaaaataaaataactggtgaat	Protospacer
    **..*********************. *** 

2. spacer 7.1|1633311|35|NC_017243|CRISPRCasFinder matches to NZ_AP018283 (Chondrocystis sp. NIES-4102 plasmid plasmid2 DNA, complete genome) position: , mismatch: 10, identity: 0.714

ctttgaagagtttaaaaataaaataactgaagaaa	CRISPR spacer
agagcaagagtttaaaattaaaataattgaagttc	Protospacer
     ************ ********.*****   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2988967 : 2996921	11	uncultured_virus(33.33%)	NA	NA
DBSCAN-SWA_2	3025258 : 3033864	8	Staphylococcus_phage(37.5%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017243|2988967:2996921|DBSCAN-SWA
TATGGAGTTAAAAGACTATATAAGAAATATTCAAGATTATCCTAAACAAGGCATACTTTTTAGAGATATTACCACATTACTTCAAAATAAAGATGCATTCAAATATGCAATAGATAAAATGGCTGAACAAATAAGCAGTGAAAAAATAGATTATATAGTCGGAGCAGAAAGCAGAGGTTTTTTAGTAGGTTCAGCATTAGCTTATAAACTAAACTGCGGATTTATTCCTGTAAGAAAAAAAGGAAAACTACCTTACAAGACTATTTCAGAAGAATATGCTTTAGAGTACGGCACAGATACTTTATATATGCATGAAGATGCTATTAAAAAAGGAGAGAGAGTTTTAATAGTAGATGATTTAATTGCTACAGGCGGAACTGCACTTGCTATGATAAAAATGGTTGAAAAATTAGAGGGTATAGTTGTAGGCTCTTCTTTCTTAATAGAGTTAAAAGAGTTAAACGGAAGAAAAGAAATAGAAAAATATCCTGTTCATGTTCTTATAGAGTATTAAAGAATATTACTATTTAATCAGTTATTGACTTTTAACATTTTTTATTATAGAATATAGCAAAAATTATTAAAAAAATTATCGAAATAAATACATTTTAAGGAGATATAAAATATGTCATCTATTAAACCATTAGCAGATAGAGTTCTTTTAAAAGTATTAGAACAAGAAGAAAAAACTTCAAGCGGAATACTTCTTCCAGATACAGCTAAAGAAAAAACTCAGAAAGCAGAAGTTATAGAAGTAGGAGACAGCGAAGATATAAAAGTAAAAAAAGGCGATATAGTTATATATGATAAATATGCTGGTATTCAAATAAAAGAAGGCGATACTGAATATTTAATAGTAAAAAATGAAGAGATAGTTGCTCTTATAAAATAATTAATAGCTATACAAATAAAAAATAAAAGAACACTAATCTTTAAAAAAAGATGGTGTTCTTTTTTACTAATTAGGGTTTTTGGCAGTTTATATTATTGTTAATAAAACTTTTTCGTATCATAAAGAATTAATAAGGTTAAATAATATAACAAATTATATTATTTAATTTTATTAATTTGTTCGATAATTAAATCATTAATTTCATTTCTTTAATCAGGAGATTTTTATAAATGCTAAAATATTTCATAATATTTCTTGCAATATTAAATATAGTATATGCTCAAGATAACACCACTAACAAAGATCCTGAATACAAATTCACTTACGAAAAAGAAAACAATTTTACAATATATAAAGAATCAGATGAAACTAATGAATCAAATACTACAAATACCCAAAATGAAATATCTATAATGCTTGAAAGAAGAGGCTTTCCTCTTGTTAATAGATTGGTAAGATTCACATCATTACACCCTGATATGTTTGATTTTGAAATAGATGAAAATCAAAAAGAAGAAATACTTTTAAAAGAAATTGATGAAAATGAAGAAACTGCATTAAACACTAATGAATCAGTTAATATGTATACAAATATATATGTAGTTCCTACAGATGAAAATGGAATAGCAAAGGCTAAACTGAATTTAAAAAATCCCGGAAATGGCGTTGTACTTATGCATATACTTTATGTAGGCTCTACAGGAAATACTAATATATCCTATGAAGAATATGCTTATGTGAATATAGAAGAAAAAAAGGAAAATCGTATATCTTCAAAACTATTAATTGGAGATAGCGATGATGTAAATATTAAAAGTTCCATATTAATAACATCAACTTTATTTCCGTCTTTATTTTTGGTATCTATAGCATTAATATTTATAAGCTACTTTAAACATATATATGAAGAATATAGAAACAGTAAATCAAAAATTATAATATATACTTTCTTTGGATTTGCATCTATCAAAAAGAATTTTGCTCTAATGATATTCATAATATTGACAGAGTTATTAATAGTAGCTTGTTTTCTGCTTTTAGACAGTTATATATTCTCTGTTATACTTATAGCATTCTTTATAGCAGGCTTCCTAATGAAAAGAGAAAAAATATATGCTATAGCCTTTTTTATACTAGCTTGTATTTCTACAATATACCTTTATCTCGAAACATTTTCCACTCATATTGCTACAGAATATATAGTCAACAATGCTGTTATGGGAAATCCTGTATTTGTCTTCTTTTTCTTTTTAATATTTACGGCATTAGCAGGAGGAATATATATACCTATATGTGTATTAATATTATATCAAACTGTATTTGTTATGAGTGATACATCTTTAATAACAGCTTTAATTGGAATATTTGTATCTTCTATATTCTATATTGTAAAAGTAAAAAAAGATATTCCTTTCCTATACAGACTTAATTTATTGAAAATAAAAGATAATAATAGGTAGTATATGGTTTTTGATTTATTAAGAGATTTAGAATTGCTTTTATCCGATATAGTTTTCAGCGGCATAAACAATATAGATTACAGCACTATAGACAAAATAGAAGTTTTAGCAAAAAGGTTTGAAAAAATTTCTATGGAAAATATAAAAAATTTATTAATAGAATTTACAGATTCATTAAAAAAATATAAAACAGATGAAGATAAAAGAACAAATATTAAAGAAGTATCAGACAATATTTCTAAAATAGAATTTTATATAAGAAATGCTTTATCTTATGAATAAAATTACTTTATCTTTTTATATATCTTTCCATTTCTCTATCTAAAGTCTTTCTTTTTAGAGTTTCTCTTTTATCATGAAGTTTCTTACCTTTTGCCAAAGCTAATTCAACTTTCACTTTTCCTCTAGCAAAATATAATTTAACAGGAATTAAAGTAAGCCCTTGTTCTTTGATTTTTCCTTGAAGTCTTTTTAATTCTCTTTTTTTCATCAAAAGCTTTCTTTCTCTTAAAGGTTCATGATTATTTCTATTTCCAAAATGATAAGGCGATATATGCATATTGACTATAAAAAGCTCTCCATTTTTTTTAAAAGAAGCATAGCTGTCAGACATATTAACACTTCTCTCCCTAAGAGATTTTACTTCTGTTCCAAGCAAAACTATACCTGCCTCAAATTTTTCTACAAGCTCATAATTAAAGAGAGCCTTTTTATTTTTTACTATTTCACCAGAAGAAATAGTGTTGCTACCTGATTTTTTATCCTTTTTACTAGCCATAATATATTACCATAATATTTAAGTATATAGATTATACTTAAAATAAATCAATTTGTCAATTATTCAATATATACAAAAAGAGCCGGAGTTTTTAATTCCAGCTCTTTTATCAAACTTTATAAATTTTAACTCATAGAATTAATCATATTATTCATATCTTCTATTTCTTTTTCCTGTGCTTTTATTATTCTGTTTGCTATCTCTTTTATTTTGTCATCTTTAGTATATTCTAATATCTTTTTAGAAACATCAATAGCAGCCTGATGATGTGGTATCATACCCTTAAGAAAATCTATATCATTATTTCCTGTTATTTCAATAACAGCCATATCAGCCATCATTTTATCCATAATAAGCTGCATCTCATTTCCTATAGCTACAGTATCAATATCACTGTAATCTGTATTTTTAGCATTCAATTCTTTGATCAATGCATCAAATTCTGTAACTTCTTTATTCTGTTCTGTTATTATATTATTAGCTAATTCTATCAAGTTTTCATTTTTAGTAGTTTCTAATAATTTTTGAGAAGAAAGAATAGCACCTTTATGATGAGGAATCATATTAAATAAAAAATCAGCATCTATATTAGCAGTTTTTTGAAAAGCCTGATCCATCATAGGCTGATGCATTAAATCAATAATTTCAGAACCAGATTTATGAGCAGTATGAGCTGAATGATCCATAGTGTTGGCATTAGTATCTGCAGTATCTGTATTTTTCTCTGAACAAGATATAAATAATAAAGCAGCTAAAGAAATAATAAATGTTGTTATAATTTTTTTCATTTTCCATCCTTTTATTTATTTTTTATCATTGATTTTTATTCAATCTAATAACTTTTATAATATGAAAAAAGTAAAAAATTATAATGATATTAAAAACTATATATAATTAAACAATATTAATCATCATCAAATATAGGCTTTTGTATTATGCATATGGTTTTATTGCTTTTATCAGAATCTCCGAAATATGCTTTAACGAAAGGTATTGAAACTATATTATTATTTTCTTTTAATTTAATTTCAAATACATAATTAGAAGGAAGGCTATATACATCTGTTATCTCACCATAAATATTATTATCAGTATCTATGATTTTGTACCCTATTAATTCAGCCTCATAAAAAGTATCATCATCTAATTGAGGCAAATACGAAGAATCTATAAATATATCAAGCCCTATTAATTTTTGAGCATCTTCTATATTATTTATATCTTTTAATTGGAACACAAAAGATTTGTTCTTCTTTTTAACATTTAACAGAGTAAATGTTTGATTGTTGATGATAACAGGTGTATCGTTAGTTAAAACAGGAAGAGAGGTAAAATAACTCTTATCAGAAAAAGCAATTTCTACCTCTCCTTTTAAACCATGTAAACCTGTGATTTTGCCGTAAAAAAAAATCAATTGTCAATAATCTCAAGCATTACACGTTTACCACTTTTCATGGAAGCTGCAAAAAGAATAGTACGTAATGCATGAGCAATACGACCTCTTTTACCTATAATTTTACCTATGTCGCTTTGGTTCACTTTCAATTCCAGAATCGTACTCTTCTCACCTTCAATAACCTTAACACTAACACCATCAGGCTCATCCACTAATTTTTTAGCCAAATACTCAATAAGCTCTTTTTCTTCCGTCATAGCACACTCCTTTATATATTATAAGACGTAAATTAAGCTTCGCTCTTCTCCTCAGCAGATTCAGGCTTAGCTTGTTTACGATGTTTGCGCCTTTTTTCAGGATTTTTCAATGCTCTTTTTTCTTTCTTTCAAGAGGAGCACCTTTATCTTTTTCCATTAAGCCTTCTTTTACAAGAATGCTTTTTACTACATAAGTTGGCTGTGCACCATTAGAAAGCCATTTTTTTAAACCTTCTACGTTCAACTTATATAATACATCTTTAGCTTTAGGGTTAAACCAACCTAGCTCTTCAATAAAACGACCATCGCGTGGGAAACGAGCATCTGCAGCTACGATACGATAATGAGGCTCATGTTTGCGACCTATACGTTTTAATCTTAATTTTACCACCTTTCTTTTCCTCCAAGTTTATTTACATTAATTTGTTTAAATCATCTATAGACATACCCATACCCTCTAGGGACTTTGCGAGCTTATCCATCTTTTTAGTACTGCCCATCATGTTTTTCATCATAGTAAATTGCTTTATAAGCTGATTTACATCATAAACACTTTGACCGCTTCCTTTAGATATTCTCATCTTTCTTGAATTATTCAAAGGAAATAGGGCTAATCTTTCTTTTTTAGTCATTGACTGTATAATAGCTTTATACTTTTTAAATTTCTCTTCTTCACGGCTTAAAAGTTCTGTATCTACATTAGCCATACCCGGAATCATAGATGTCATTTTACTGAGTCCGCCCATTTTAGCAGTAGCTTCTATCTGCTTCAAGAAATCATTATAATCGAAATTGTTCTCTATAACTTTCTGAAGCATTTCCTGAGCTTCTTTTTCACTTATAGCAGCACGGGCTTTTTCTACTAATTTTACTATATCACCCATACCGAGTATTTGTCCTGCCACCCTCTTAGCATCAAATACATCAATATCATCTAAATGCTCACCTACTCCGACAAACTTAACAGATGAACCTGTGGCATATTTTAGAGATAAAGCGGCACCGCCTCTAACTCCGGAATCGAATTTTGTAAGTATAACACCATTAATGCCAATATTGTTTTGGAAACTTTTTGCAACATCATAAACACTTTGACCTGCTGTAGAATCCACAACTAATAATTTTTCTGTAACATTAGCAGAGTTTACAACACGTCTTAGTTCAAGCATCATTTCTTCATCTATCTCTAAGCGTCCTGCAGTATCCACTAATATCATATTATACTGCTCTTTTTTAGCAATTGAAAGTGCTTTTTTAAGTATTTTATATGCTTTTTTCTCTTTAGTATCTATATGATAAGGAACACCAACTTCCCTAGCCAAAACGGCAAGCTGTTCCATAGCGGCAGGTCTGTGAACGTCAAGTCCTACAAGCATAACGCGTCTTTTATCTTTATAATACTTAGCCAATTTAGCAGAAGTAGTAGTTTTACCAGAACCCTGAAGTCCGAAAAGCAAAGTTATAGTTGTTTTCTCAACAGGCTCTAATTTCAAACCGCTTTCACCCTCGCCTATCATATTAACCAAAGTATCATGAACATCAGCTACAAACTGATTAGCAGGCTCTACACCTTCTAATTTTTCTTTTCCTATAGCTCTATTAGTAGCTTCTTCAAGAAACTTGTCAGCAGCTTCTAAAGATACGTCAGCAGAAAGTAATGCTTCTTTTATAGTTAACAAACTATCTGTTATATCCTTATCTGTTAGGACTTTTTTTCCTTGTATTTTAGAGAATACATTAGATATAGATTTAGTTAAATTACCAAACACTAAAAAACAACCTTATAAACATATTAATTCCAAGTCATATTATACATAATATATTTAAAAAGTCAATATTTAGCACAATTTTACAAAAAATTATATATAATAATAAAGAGCACAGTAATACATTTAAAACATTATTATCAATTTAATTTAAGTTTGCTGCTTAAGGCCTTACTTATATCTTTAGTTCCACTTGCTCCTACAGATGTTAAAAAGAATTTTTTATTAATCAATTTTTCATCTATTACTTCATTAACCAGTTTCAAATCTATTTTATCTATTATGTTATAAAGTTCTTTAAATGAAATATATTTAGATGAATACAGTTCATGTCTGGCATTTTTATTCATTATAAACTCAGCACTGAATTTACTAAATGCCATAGAACCTTTATAACTCTCTTTTGCCTCTTCAATCTCTTCTTCTGATATCCTTTCATTAACCAATCTTTCTATTTCATAATATATACTTTCTATAGTTTCTGCATATCTGTCCAAACTAGTAGAACCATGTATCTCAAATGTACCGCCATTTATAAAACTAGAATTATAACTGTATATATTATAACAAAGTCCTTTATTCTCTCTTATTGATTGAAATAATCTTGAATAAGAACTTCCTCCGAATATATCATTAACTATATTCATAGCATATCTTTTTTTATTATCGCAGGCATTATATGAAGGTGTTACTAATGAAAAATAAACCTGATTAATTTCTTGTTTCTCTTTAGTGATAGTTTTATAATAAAAAGGAAGCTCATCATTAACTGTTCTAGTTTTTTTTTCTAATTTTATTTTTTCAAGTCTATCTACAGCATAATCAATATCAAAATTTCCGGCTATAGATATAATTAAATTATTAGAATTAAAATGTTCCTTAAAATAAGAATAAATTTTATCTCTGCTTATCTTTTTTATATTATTAATATTTCCGCCTATAGGAAAACTCATAGAAGTACCTTTATAGGCAGCAGCAAAAAATTGATTAGCTGATATTTCTTCAGGGGTATCATTTGACATTTTAAGCTCTTCAATGATAACTTTTTTTTCTCTGTTTATATCATCTTCTCTGAATGCAGAATGAAGCATGATATTTTCTAAAGTATCAACTGCCCTATCAAAATATTTAGATATTATGTTAATATAAAATGAAGTTAAATGTCTTGAAGTAAAAGCATTAAATATACCGCCCACACCTTCTATATTTCTAATAAGTTCTTTTGAACTAATTTTGTCAGTTCCTTTAAAAAGCATATGCTCTATGAAATGAGTATATCCGTTTTCCTCTTTTTTCTCATTAGCACTTCCTGTTAAAAATATAAAACCTATAGATACAGTATCAAGCATAGGCATCTTTTCTAAAACAACCCTTGTACCATTTTTTAATGTTAATCTTTTTACCAT

Protein sequences of DBSCAN-SWA_1

>NC_017243|2988967:2996921|2993000_2993510_-|WP_041177493.1|DBSCAN-SWA
MIFFYGKITGLHGLKGEVEIAFSDKSYFTSLPVLTNDTPVIINNQTFTLLNVKKKNKSFVFQLKDINNIEDAQKLIGLDIFIDSSYLPQLDDDTFYEAELIGYKIIDTDNNIYGEITDVYSLPSNYVFEIKLKENNNIVSIPFVKAYFGDSDKSNKTICIIQKPIFDDD
>NC_017243|2988967:2996921|2991607_2992096_-|WP_014489037.1|DBSCAN-SWA
MASKKDKKSGSNTISSGEIVKNKKALFNYELVEKFEAGIVLLGTEVKSLRERSVNMSDSYASFKKNGELFIVNMHISPYHFGNRNNHEPLRERKLLMKKRELKRLQGKIKEQGLTLIPVKLYFARGKVKVELALAKGKKLHDKRETLKRKTLDREMERYIKR
>NC_017243|2988967:2996921|2988967_2989480_+|WP_014489034.1|DBSCAN-SWA
MELKDYIRNIQDYPKQGILFRDITTLLQNKDAFKYAIDKMAEQISSEKIDYIVGAESRGFLVGSALAYKLNCGFIPVRKKGKLPYKTISEEYALEYGTDTLYMHEDAIKKGERVLIVDDLIATGGTALAMIKMVEKLEGIVVGSSFLIELKELNGRKEIEKYPVHVLIEY
>NC_017243|2988967:2996921|2994162_2995518_-|WP_012671545.1|DBSCAN-SWA
MFGNLTKSISNVFSKIQGKKVLTDKDITDSLLTIKEALLSADVSLEAADKFLEEATNRAIGKEKLEGVEPANQFVADVHDTLVNMIGEGESGLKLEPVEKTTITLLFGLQGSGKTTTSAKLAKYYKDKRRVMLVGLDVHRPAAMEQLAVLAREVGVPYHIDTKEKKAYKILKKALSIAKKEQYNMILVDTAGRLEIDEEMMLELRRVVNSANVTEKLLVVDSTAGQSVYDVAKSFQNNIGINGVILTKFDSGVRGGAALSLKYATGSSVKFVGVGEHLDDIDVFDAKRVAGQILGMGDIVKLVEKARAAISEKEAQEMLQKVIENNFDYNDFLKQIEATAKMGGLSKMTSMIPGMANVDTELLSREEEKFKKYKAIIQSMTKKERLALFPLNNSRKMRISKGSGQSVYDVNQLIKQFTMMKNMMGSTKKMDKLAKSLEGMGMSIDDLNKLM
>NC_017243|2988967:2996921|2990088_2991318_+|WP_014489035.1|DBSCAN-SWA
MLKYFIIFLAILNIVYAQDNTTNKDPEYKFTYEKENNFTIYKESDETNESNTTNTQNEISIMLERRGFPLVNRLVRFTSLHPDMFDFEIDENQKEEILLKEIDENEETALNTNESVNMYTNIYVVPTDENGIAKAKLNLKNPGNGVVLMHILYVGSTGNTNISYEEYAYVNIEEKKENRISSKLLIGDSDDVNIKSSILITSTLFPSLFLVSIALIFISYFKHIYEEYRNSKSKIIIYTFFGFASIKKNFALMIFIILTELLIVACFLLLDSYIFSVILIAFFIAGFLMKREKIYAIAFFILACISTIYLYLETFSTHIATEYIVNNAVMGNPVFVFFFFLIFTALAGGIYIPICVLILYQTVFVMSDTSLITALIGIFVSSIFYIVKVKKDIPFLYRLNLLKIKDNNR
>NC_017243|2988967:2996921|2989591_2989858_+|WP_008722116.1|DBSCAN-SWA
MSSIKPLADRVLLKVLEQEEKTSSGILLPDTAKEKTQKAEVIEVGDSEDIKVKKGDIVIYDKYAGIQIKEGDTEYLIVKNEEIVALIK
>NC_017243|2988967:2996921|2993855_2994140_-|WP_049783513.1|DBSCAN-SWA
MVKLRLKRIGRKHEPHYRIVAADARFPRDGRFIEELGWFNPKAKDVLYKLNVEGLKKWLSNGAQPTYVVKSILVKEGLMEKDKGAPLERKKKEH
>NC_017243|2988967:2996921|2995655_2996921_-|WP_014489043.1|DBSCAN-SWA
MVKRLTLKNGTRVVLEKMPMLDTVSIGFIFLTGSANEKKEENGYTHFIEHMLFKGTDKISSKELIRNIEGVGGIFNAFTSRHLTSFYINIISKYFDRAVDTLENIMLHSAFREDDINREKKVIIEELKMSNDTPEEISANQFFAAAYKGTSMSFPIGGNINNIKKISRDKIYSYFKEHFNSNNLIISIAGNFDIDYAVDRLEKIKLEKKTRTVNDELPFYYKTITKEKQEINQVYFSLVTPSYNACDNKKRYAMNIVNDIFGGSSYSRLFQSIRENKGLCYNIYSYNSSFINGGTFEIHGSTSLDRYAETIESIYYEIERLVNERISEEEIEEAKESYKGSMAFSKFSAEFIMNKNARHELYSSKYISFKELYNIIDKIDLKLVNEVIDEKLINKKFFLTSVGASGTKDISKALSSKLKLN
>NC_017243|2988967:2996921|2991321_2991600_+|WP_014489036.1|DBSCAN-SWA
MVFDLLRDLELLLSDIVFSGINNIDYSTIDKIEVLAKRFEKISMENIKNLLIEFTDSLKKYKTDEDKRTNIKEVSDNISKIEFYIRNALSYE
>NC_017243|2988967:2996921|2993506_2993749_-|WP_014489041.1|DBSCAN-SWA
MTEEKELIEYLAKKLVDEPDGVSVKVIEGEKSTILELKVNQSDIGKIIGKRGRIAHALRTILFAASMKSGKRVMLEIIDN
>NC_017243|2988967:2996921|2992221_2992884_-|WP_041177492.1|DBSCAN-SWA
MKKIITTFIISLAALLFISCSEKNTDTADTNANTMDHSAHTAHKSGSEIIDLMHQPMMDQAFQKTANIDADFLFNMIPHHKGAILSSQKLLETTKNENLIELANNIITEQNKEVTEFDALIKELNAKNTDYSDIDTVAIGNEMQLIMDKMMADMAVIEITGNNDIDFLKGMIPHHQAAIDVSKKILEYTKDDKIKEIANRIIKAQEKEIEDMNNMINSMS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014489034.1|2988967_2989480_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.5e-31	44.7
WP_008722116.1|2989591_2989858_+	co-chaperone GroES	A0A221S4G8	uncultured_virus	5.8e-06	34.9
WP_014489035.1|2990088_2991318_+	hypothetical protein	NA	NA	NA	NA
WP_014489036.1|2991321_2991600_+	hypothetical protein	NA	NA	NA	NA
WP_014489037.1|2991607_2992096_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.5e-31	49.7
WP_041177492.1|2992221_2992884_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	7.2e-13	34.4
WP_041177493.1|2993000_2993510_-	16S rRNA processing protein RimM	NA	NA	NA	NA
WP_014489041.1|2993506_2993749_-	KH domain-containing protein	NA	NA	NA	NA
WP_049783513.1|2993855_2994140_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_012671545.1|2994162_2995518_-	signal recognition particle protein	D6PHS7	uncultured_phage	4.6e-06	31.7
WP_014489043.1|2995655_2996921_-	insulinase family protein	G3MBJ8	Bacillus_virus	1.4e-36	32.0

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017243|3025258:3033864|DBSCAN-SWA
TATGAAAAAATTATATAAAAATCTATATGTAGGTAATGACAGAGATTGCGAAGAGTTTAAAGGGGCTATAGTTCATGCTTGCCAAAGCTGTTTTGTTAGAGGCGTAAGAGGAAATATAGGCGATAAAAAAGTGTATCAAAATAATAATGATTTATATTTGAATTTACTTGATATAAGCAGCTTATCTTTTGAATATGCTTTTCCTATGATAAAGAGAGCTATGGAGTTTATAGATGAACATATAAATGATATGGAAGTATTAGTTCATTGTAATTTTGGTATGTCAAGATCTCCATCTATAGCACTTCTTTATATGGCAAGAAAAGGCTATATAAGTAATACTTCATTCAAAGATGCTTTAAGAGATTTTCATGAAATATACACTTACTATTCACCTGGAATGGGAATGTATAGATACTTCGATAATTATTGGTATGAAATAATGAGTTTTTAGAAAAATAAGATATATAAAGCTAAAAATAATTTTTTGACAAATATAAATTATAATTATATAATCCGAATAATTAAGCTATAATGTAAATTTAATATATTAGGAAATCATATAATGTGCAGATTTATTGATTTATTTGCAGGAGTAGGAGGTTTTCATTTAGCCTTTAATTCTGAATATTGTGTTTTTGCCAGTGAGATAGATAAATACGCAAGTGAAACATATAAATTAAATTTTCCTGATACAAGGTTAGAAGGGGATATTACAAAAATAGATGAAAAAGATGTTCCGGAACATGATATTCTTTGTGCCGGTTTTCCTTGTCAGCCTTTTTCTGTAGCAGGTTATAGAAAAGGGTTTGAAGATGTAAGAGGTACTTTGTTTTTTGATATTGCCAGAATAATTAAATATCATAGACCTAAAGCAGTATTATTGGAAAATGTTAAAAATCTTGAAAATCATGATAATGGTAATACTCTTAAAACAATAATAAATGTATTGCAAGATTTAAATTATTATGTATGCTATAAAATTTTAAATTCTGCTGAATATTCAAATATTCCTCAAAATAGGGAAAGAATCTTTATTGTAGCTTTTAATAAAGATACAGTATTAAATTATTCTTATTTTAAATTTCCTGAACCTGTAGAATTAACTAATACTATTCATGATTTTATAGATCAAGAAAAACAAGATGATGTTTTTTATTATAATAATACTAAGTACTATGAAATTTTTAATGAAGGAATGCTTAATAAAAATACCGTTTATCAGTGGAGAAGACATTATATAAGAGAAAATAAATCTAATTTATGTCCAACTTTGACAGCTAATATGGGAGAGGGGGGGCATAATGTTCCTATAATACGCGATGATTATGGTATAAGAAAATTGACGCCAAGAGAATGCTTTAATTTTCAAGGATATCCTAAAAATTTTAAACTTCCAAATCAATCAAATTCTAAATTATATAAACAAGCTGGTAATTCTATTGTTTATCCTTTAGTAAAAAAGATAGCAGATAATATTCTTAAAGTTATAAATAATATCAATATGTCTGAGGAAACAAATGCTGAATTTTTTTGAATTAGATAAAAAAGAAAATAAAAATTATGTCAATTTAATGAAAATAGTTGCAAAACTTTCTAGGTTATATAGTGACAGCGATACTCCATATATATATTATAGAGCTATGGAGAACTTATTTTGCTATTGTTTTGGAGCTAAAAATTTAAGCAGATCAGATATTGCATTTGATGCTAAATTAGGAAATCTTGGAATAGGATTAAAAACTTTTGTTGGTGAAAATAAAGATTATAGTTTTGAAAAAATAGCAGAATTTAATAAAGATTCAAAACTTATAAAAGATAAAAAAGATGAAAGAGAGATAATGGAATTTCTTGCTAATTTAAGGAATGATAGAATTAATCTTGCCAAGAACCTTTATGGAATATCAGAATCTTTATATCATATTATAGCAAGAAGAAAAAAATCACTCTTATTTTTTGAAACAGATTATAACGAAATTGATATTTCAAACTTAAGAATAGAAAGGCAGAAAGGAAGTAAAGAAGAAAAGTCTTTAAATTTTACAGATGGAAATCATTTATATAAGTTTAATTTCTCAAAAAGTACTTTATTTAGAAGATTTGATATTCCTAAAGAAAGTTCCTGCACAGATGTAGTTATATTTGAAAATCCTGCAGAACTTTTATTGTCAATTGATGAAATTACATATAACTTTAAACCTAAATGTGAATATGTTATTCTTCCATTGTATACAGTAAAAGAAGGAAAAAAAATAGTTCAGGAAAAATCTGCTTTGAATCAATGGAATGCAGGCGGAAGAAAGAGGGATCCTGATGAAGTATATATTACAATACCTTCATTTATAAGAAATAATTTTCCTAATTTTTTTCCAGGAAGGGATACTCCATTTATTTTGAAAACTCCTATAGGTGAAATATTAAATGCTAAAGTATGTCAAGATAATAATAAAGCATTAATGACAAATCCTAACAAAGCATTAAGTAATTGGCTTTTGAGAAATATTCTCAAATTAAAAGAATTAGAACTTGCTACTATTGAGAGATTAGAAATTTTAGGTATAGATTCTGTCATAATAACTAAGGAAAAAGCTGGAGAGTATTCTATAGATATACAAAGCTGGGGAAGTTATGAAAGATTTATAGAAGAAGTAAAAACAAACGAAAATTAATTTTATATTGGAGTTACTAATAATGTCAGATACAAAAACTCCTGAAGAAAGAAGCCGAAATATGGCAAGAATAAAAAGTGAAAATACAAAACCTGAAAATATTGTTAGAAAATATCTTTTTAAACATGGATTTAGATATAGAAAAAATGATAAAAGATATCCCGGCAAACCAGATATCGTACTTCCAAAATATCATACTATAATTTTTGTCAACGGATGTTTTTGGCATATGCATAACTGTTCAAGAGGAAGAATGCCTCTTTCTAATAAAAGCTATTGGGTACCTAAAATAAAACGCAACATAGAAAGGGACAAAAATAATATAATAAATTTAGAATCAATGGGATGGAAAGTTATTGTAATTTGGGAATGTGAACTAAAAAATAAAATTGCAGAAGAAAGACTGAAAAAGTTATGTGAAGAAATAATAAATGATAAAAATTAATAATATATTACTGATGCTTGACAATATAAAATATTTGTATTATACTATTACATATAAATCTTCGGGGCTAGGTGAAATTCCATACCGGCGGTAAAGTCCGCGAGCCTTTTTGATGTTCCTCATTCAAAAACGGCAGATTTGGTGCGATTCCAAAACCGACAGTTAAAGTCTGGATGGTAGAAGATAAAATTAATGTAAACTACTACATAAAATAATGGCTCTAATTGTTATTTTTAACATTTAGAGTTTTTTTGTTTACAAGTCAAAAAATCCGCCAATTAAAAACCTCAAAGATTAATAAAAAATATTTTTTAAGAGTATTAGCATTATGCAGAACAATATGCATGAAAAGTACATGAAAATGGCTATAGAGGAAGCTAAAAAAGGAGAAGGTTTTACAAGTCCTAATCCTTTGGTTGGTGCTGTTATAGTGAAAGACGGAAAAGTTATAGGCATTGGATACCATAAAAAATGCGGTGAAAATCATGCAGAGATTAATGCTTTTTTAGATGCCAAAGAAAAAGGCGAAAATGTTGAAGATGCTGATATATATGTAACTTTAGAGCCTTGTTCTCATTATGGAAAAACTCCTCCTTGTGCTGATGCTATTATAAAAAATAAATTAAAAAGAGTGATTATAGGATGCGTTGATTCTAATCCCAAAGTAGCAGGAAATGGCATAAAAAAATTAAAAGATGCTGGCATTGAAGTTATAGTAAATGTGCTTGAAGAAGAATGCAGAAAATTAAATGAGGTTTTCTTCTATTATATAGCTAATAAAAGACCATTTATTGTTATGAAATATGCTATGACTATTGATGGTAAAATAGCTACTGTAAGCGGAAAATCAAAATGGATAACTTCAGAAAAAACTAGAGAGCATTCTCATAGATTTAGAAATAAATACTCTGCTATAATGGTTGGAATAAATACTGTAATAGAAGATAATCCTACACTTAATTGCAGACTTCCAAATACTAGAAATCCTATAAGAATAATTTTGGATAGTTCTTTAAAAATAGATTTGTATTCTAATATTTGTAAAACTGCTAAAGAAATAAAAACTTTTATAGCTACTATTAGCGATGATGATAAAAAAATAAAAGAACTTGAAAGTTTTGGTATAGATATAATAAAAACAGAAAATGATAATGGCAAAGTTAGTTTAAAAGATTTGATGAGAATACTCGGAGAAGAAAAAGATATTGACAGTGTGTATGTTGAAGGCGGTGCTGCTTTACATGCGAGTTTATTAAAAGAAAAGCTAGTAAATAAGGCTTTGATTTATATAGCACCAAAAATATTCGGAGGTCTTGAAGCAAAAAGCCCTATAGGAGGCGAAGGGATAGATGATCCTAATGATGCTGTTAAACTTACTGAAGGCAGCATAACAAAAATAGAAGACGATTTATTTTTAGAGTATTACTTACAATATTAATAGATAAATTTTATTATTAAATTAATATACCTTGTGCTTTTTGGTACTTTTTGCCACGGGAAAAAGTACAGAAATTATTTAAGAGAGAAAATATTAATAATGTTTACTGGTATAGTTGAAGAAATAGGAACTGTTAAATCTGTACAAAGCAAAGTTATCACGATAGAAGCAAGCAAAATATTCGATGATTTGCACTTAGGTGATAGTGTTGCTGTTAATGGTACTTGTTTAACAGTATCTAGTTTTGATAATAAAATATTTAATGCAGATGTTACTCAAGAAACTTTGAACCGTACTAATTTAGGAAGTTTAAAAAACGGAAGTAAAGTTAATCTTGAAAGAGCTATGACTTTAAGCGGAAGATTTGGCGGTCATATAGTAAGCGGACATATTGACGGAGTGGGAAGCATTAAGTCTATGAAGAAAGATGACAATGCTATAATACTCACTATTGAAGTGCCTAAACACTTAATGAAGTATATAGTAGAAAAAGGTTCTGTTGCTGTTGACGGCATAAGTTTGACAGTGGCAAGTTTAACCGATAATACTTTTTCTATAGCGGTTATTCCTCATACATTGAAGGAAACTGTACTTTATTATAAAAAAGAAGGTGATAAGGTTAATATTGAAAATGATGTTATAGGCAAATATGTTGAAAGGCTTTTAACATTTAAAGAAGATAATGATGATAGTAAAAAATCCAATATAACAATGGACTTTTTACTTAAAAATGGTTTTTAATAATTATGCACTTTTTACAGCTTTTTACAGCTAATAAATATTAGGAAAAAGTTGAATAAAAAATAAAAATGGAGCATTAAAAATGGAAAATGTTTACAGCACTATTGATGAAGCTTTAGAGGATTTAAGAAACGGAAAAATTATAGTTGTTTCTGATGATGAAGATAGAGAAAATGAAGGCGATTTAATCTGTGCGGCAGAATTTGCTACTACAGAAAATATCAACTTTATGGCTACTTATGCTAAGGGTTTGATATGTATGCCTATGAGTAAAGAAATTACTAATAGATTAAATTTAAATCAAATGGTTACAAAAAATACTGATAATCATGAAACAGCTTTCACAGTATCTATTGACCATGTTGAAACTACAACAGGTATATCAGCAGTTGAAAGATCTATCACAGCTTTAAAAGTTATTGATGAAAATGCTAAACCTGAAGATTTTAGACGTCCCGGTCATATGTTCCCATTACTTGCAAAAGAAGGCGGAGTATTAGTAAGAATGGGACATACTGAAGCTACTGTTGATTTGATGAGATTAGCAGGTTTAAAAGAATGTGGTTTATGCTGCGAGATTATGAGAGATGACGGTGATATGATGAGAAGAGATGATTTGATTGATTTCGCTAAAAAACATAATCTTAAAATGATAACTGTTTCTGATTTGATTGATTATAGAAAAAAGAATGAAGATTTAATGGAGCTTTATGCTAAGGCTAAAATGCCTACTAAATATGGTGAGTTTGAAATACTTACTTTCGTAAATAAAATCACAAAAGAACATCATGTAGTTTTAACTATGGGAGATATTTCAAGCGGAGAAGATGTACTTTGCAGAGTTCATTCTGAATGTTTGACAGGCGATGCATTAGGCTCAAAAAGATGCGATTGCGGTGAACAGTATGATTATGCTATGAGAAAAATTGCTGAGGAAGGCAGGGGCATCATGGTTTATATGCGTCAGGAAGGAAGAGGAATAGGACTTGTTAATAAATTAAGAGCTTATGAACTTCAGGACAGCGGACTTGATACAGTTGATGCTAATATAGCTTTGGGCTTCAGAGATGATATGCGTGAATATTATGAGGCTTATCAAATGCTTAAAAATTTAGGTATTAAGAGCATAAAAATAATGACTAATAACCCAGATAAAATAAAGTATTTGAATAATTACGGCTTAGAGATAAAAGACAGAGTACCTATACAGATAGAAGCTTCAGAGTATGATGCATTTTATCTAAAGACTAAAAAGGAAAGAATGGGTCATATTTTAGATTAAAAAACTTGTGAGTGCCTGACATTTGCAAAAATGTCAGGGCCTATCAACGAACAAGTTTTTTATATATATATAAAACGTATGGGCCATATATAGATTGAATTTAAAAATAAAAAATTACGAGCCTCTGTAAACTGACAAAGGAAGTTGCTAGAGCTTATCACAATAGACATACAAAGCAAGCTAGTAATTTTTTATGATATAGACTAGCATTTTGACATTTATATTAATTTTATTATAATGTTTGTATTATGGATAATGTAAAATATTTTAATACATTGAATGATTATTTTGTAAGATATCTTTTATCTGATAGAGGAAGTGAAGCAATATTGTTGGATTTTATTAATTCAATAATGCTTGACTCCAATATGAAAACATTTAGAAGTGTTGAAATACTAACTCCATTTAATTATAAAGAAAATTATGAAGATAAAGAAACAATTACAGATGTAAAATGTATAACTCAAAATGGCTCAGTTGTTGTAATAGAGATTCAGCTTCAAGGAAATTCAAGGTTTCCAGAGAGAATACTTTATTATTGGGCTTCTAATTACAGCAAACTTTTAAAGCAGGGTGAAAAATATGATGCTCTAACTCCTGTAATTAGTATTAATCTTCTTAATTTTAATTTAGATGATTCAGAAAATATTCATTCCTGCTATATGATTTATGATACAGGTAATCAAAGATTATTAACTGATCATTTACAAATACACATAATTGAAGTAAAAAAATTTAAATACAATTTATTAAAACCTGATTTAAATTGCTGGCTTAAATTTTTTACTATAAAGGAAAGTGATAATAAGTAGGTTATAATGTCAGAATTAGTAAAAGAAAAGCCTATAATGGAAGAAGTACAAAGAAGATATAATAACTTCATTAAAGATAGATTGATGATGAATGAATATGATAAAAGACAAGCATATTTATATGGTAATCAAATAATGCTTGAAGAAGAACGAAGACTAGGAATTGAAGAAGGTAAAAAAGAACAGCAAATATCTATAGCTAGAAACTTTAAAAAAGCCGGCATAGATATAAAAATAATTAGTGAAAATACAGGTTTGAGTATAGAAGAAATAGAAAACTTGTGAGTATATGGCATTTACAAAATGTCAGGGTTCTAGCAAATTTAAAATATAAAGCTAGATAAATTGCGAGCCTCTGGAAACTAATAAAGAAAATTGCTAGAACTTATTTCCATAGGCATTAAAGCGAGCCAAGCAAGTAGGCACCTTTACGGGTGGCATAGCAATAATAAGAAAAAGCGAGCCGAAGCCAGCTAGTGAGTTTACTCGCTAGCTTATTTAAGGCGTAGGCAAGCATAGCAATAATAATAAAATTTTCTAGCAAATTTAAAATATATAAAGCTAGATAAATTGCGAGCCTCTGATAACTGACGAAGGAAGTTGCCAGAGCCTAGATAGCGAGCAATTTTCTAGCAAATTTAAAATATATAAAGCTAGATAAATTGCGAGCCTCTGGTAACTGACGAAGGAAGTTGCCAGGGCCTAGATAGCGAGCAATTTTCTAGCAAATTTAAAAAAGGATAGTTAATATGAAAACTTTTGAAGGAAAACTCGTTAGTGAAAAACCAATTAAAATCGGTATAGTGTGTGCTAGATTCAATGAATTCATTGTTTCTAAACTTTTGGGCGGTGCTTTAGATGCTTTATCTCGTCATAACATAAAAGACGATGATATTACTGTAGCTTGGGTGCCTGGTGCTTTTGAGATACCTCTAATAGCTTCTAAAATGGCTAAATCTAAAAAGTATGATGCTGTTGTTTGTTTGGGTGCTGTTATAAGAGGTTCTACTACTCATTATGATTATGTTTGTGCTGAAGTTTCTAAAGGTATTGCCAATGTTTCTCTTAATTCTGATATACCTGTAATGTTCGGCGTACTTACTACTGAAAACATTGAACAGGCTATTGAAAGAGCAGGAACTAAAGCTGGAAACAAGGGATTTGATTCTGCTATGGCTGCTATTGAAATGGTTAATTTAATCAGAGAGATAGAAAAGTAA

Protein sequences of DBSCAN-SWA_2

>NC_017243|3025258:3033864|3029908_3030550_+|WP_014489069.1|DBSCAN-SWA
MFTGIVEEIGTVKSVQSKVITIEASKIFDDLHLGDSVAVNGTCLTVSSFDNKIFNADVTQETLNRTNLGSLKNGSKVNLERAMTLSGRFGGHIVSGHIDGVGSIKSMKKDDNAIILTIEVPKHLMKYIVEKGSVAVDGISLTVASLTDNTFSIAVIPHTLKETVLYYKKEGDKVNIENDVIGKYVERLLTFKEDNDDSKKSNITMDFLLKNGF
>NC_017243|3025258:3033864|3030632_3031832_+|WP_014489070.1|DBSCAN-SWA
MENVYSTIDEALEDLRNGKIIVVSDDEDRENEGDLICAAEFATTENINFMATYAKGLICMPMSKEITNRLNLNQMVTKNTDNHETAFTVSIDHVETTTGISAVERSITALKVIDENAKPEDFRRPGHMFPLLAKEGGVLVRMGHTEATVDLMRLAGLKECGLCCEIMRDDGDMMRRDDLIDFAKKHNLKMITVSDLIDYRKKNEDLMELYAKAKMPTKYGEFEILTFVNKITKEHHVVLTMGDISSGEDVLCRVHSECLTGDALGSKRCDCGEQYDYAMRKIAEEGRGIMVYMRQEGRGIGLVNKLRAYELQDSGLDTVDANIALGFRDDMREYYEAYQMLKNLGIKSIKIMTNNPDKIKYLNNYGLEIKDRVPIQIEASEYDAFYLKTKKERMGHILD
>NC_017243|3025258:3033864|3026777_3027926_+|WP_014489066.1|DBSCAN-SWA
MLNFFELDKKENKNYVNLMKIVAKLSRLYSDSDTPYIYYRAMENLFCYCFGAKNLSRSDIAFDAKLGNLGIGLKTFVGENKDYSFEKIAEFNKDSKLIKDKKDEREIMEFLANLRNDRINLAKNLYGISESLYHIIARRKKSLLFFETDYNEIDISNLRIERQKGSKEEKSLNFTDGNHLYKFNFSKSTLFRRFDIPKESSCTDVVIFENPAELLLSIDEITYNFKPKCEYVILPLYTVKEGKKIVQEKSALNQWNAGGRKRDPDEVYITIPSFIRNNFPNFFPGRDTPFILKTPIGEILNAKVCQDNNKALMTNPNKALSNWLLRNILKLKELELATIERLEILGIDSVIITKEKAGEYSIDIQSWGSYERFIEEVKTNEN
>NC_017243|3025258:3033864|3028711_3029809_+|WP_041177649.1|DBSCAN-SWA
MHEKYMKMAIEEAKKGEGFTSPNPLVGAVIVKDGKVIGIGYHKKCGENHAEINAFLDAKEKGENVEDADIYVTLEPCSHYGKTPPCADAIIKNKLKRVIIGCVDSNPKVAGNGIKKLKDAGIEVIVNVLEEECRKLNEVFFYYIANKRPFIVMKYAMTIDGKIATVSGKSKWITSEKTREHSHRFRNKYSAIMVGINTVIEDNPTLNCRLPNTRNPIRIILDSSLKIDLYSNICKTAKEIKTFIATISDDDKKIKELESFGIDIIKTENDNGKVSLKDLMRILGEEKDIDSVYVEGGAALHASLLKEKLVNKALIYIAPKIFGGLEAKSPIGGEGIDDPNDAVKLTEGSITKIEDDLFLEYYLQY
>NC_017243|3025258:3033864|3033393_3033864_+|WP_012671528.1|DBSCAN-SWA
MKTFEGKLVSEKPIKIGIVCARFNEFIVSKLLGGALDALSRHNIKDDDITVAWVPGAFEIPLIASKMAKSKKYDAVVCLGAVIRGSTTHYDYVCAEVSKGIANVSLNSDIPVMFGVLTTENIEQAIERAGTKAGNKGFDSAMAAIEMVNLIREIEK
>NC_017243|3025258:3033864|3025258_3025711_+|WP_014489064.1|DBSCAN-SWA
MKKLYKNLYVGNDRDCEEFKGAIVHACQSCFVRGVRGNIGDKKVYQNNNDLYLNLLDISSLSFEYAFPMIKRAMEFIDEHINDMEVLVHCNFGMSRSPSIALLYMARKGYISNTSFKDALRDFHEIYTYYSPGMGMYRYFDNYWYEIMSF
>NC_017243|3025258:3033864|3025822_3026794_+|WP_014489065.1|DBSCAN-SWA
MCRFIDLFAGVGGFHLAFNSEYCVFASEIDKYASETYKLNFPDTRLEGDITKIDEKDVPEHDILCAGFPCQPFSVAGYRKGFEDVRGTLFFDIARIIKYHRPKAVLLENVKNLENHDNGNTLKTIINVLQDLNYYVCYKILNSAEYSNIPQNRERIFIVAFNKDTVLNYSYFKFPEPVELTNTIHDFIDQEKQDDVFYYNNTKYYEIFNEGMLNKNTVYQWRRHYIRENKSNLCPTLTANMGEGGHNVPIIRDDYGIRKLTPRECFNFQGYPKNFKLPNQSNSKLYKQAGNSIVYPLVKKIADNILKVINNINMSEETNAEFF
>NC_017243|3025258:3033864|3027948_3028371_+|WP_014489067.1|DBSCAN-SWA
MSDTKTPEERSRNMARIKSENTKPENIVRKYLFKHGFRYRKNDKRYPGKPDIVLPKYHTIIFVNGCFWHMHNCSRGRMPLSNKSYWVPKIKRNIERDKNNIINLESMGWKVIVIWECELKNKIAEERLKKLCEEIINDKN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014489064.1|3025258_3025711_+	phosphatase	A0A2I7QW36	Vibrio_phage	6.2e-08	33.6
WP_014489065.1|3025822_3026794_+	DNA cytosine methyltransferase	V5URQ5	Oenococcus_phage	9.3e-86	52.7
WP_014489066.1|3026777_3027926_+	restriction endonuclease	V5US45	Oenococcus_phage	1.8e-32	27.6
WP_014489067.1|3027948_3028371_+	DNA mismatch endonuclease Vsr	E5E3X5	Burkholderia_phage	2.5e-27	45.8
WP_041177649.1|3028711_3029809_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.0e-52	37.9
WP_014489069.1|3029908_3030550_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.8e-46	47.9
WP_014489070.1|3030632_3031832_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.8e-113	53.0
WP_012671528.1|3033393_3033864_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.4e-39	52.0