CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017380	Helicobacter pylori SNT49 plasmid pHPSNT, complete sequence	0 crisprs	NA	0	0	0	0
NC_017376	Helicobacter pylori SNT49, complete genome	3 crisprs	cas2,csx1,DEDDh	0	4	0	0

1. NC_017376

CRISPR-Cas detection and classification

Crispr_ID: NC_017376_1

• CRISPR_ID: NC_017376_1
• CRISPR_location: 375348-375491
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_017376_1

Consensus_repeat	Method
AGAAAGGCTCTCTAGCGTTACTGAAGAAATCATTTCAAAAAAACAAGAAGAATT	CRISPRCasFinder

spacers of NC_017376_1

>1.1|375402|36|NC_017376|CRISPRCasFinder
ACAGAGCAAAGAAACCAAAGAGGGTAAGCATGATGG

CRISPR arrays and Neighbor proteins around NC_017376_1

CRISPR arrays

The CRISPR arrays of NC_017376_1

>merge|NC_017376|1|375348-375491|CRISPRCasFinder
AGAAAGGCTCTCTAGCGTTACTGAAGAAATCATTTCAAAAAAACAAGAAGAATTACAGAGCAAAGAAACCAAAGAGGGTAAGCATGATGGAGAAAGGCTCTCTAGCGTTACTGAAGAAATCATTTCAAAAAAACTAGAAGAATT

>NC_017376|1|1|375348-375491|CRISPRCasFinder
AGAAAGGCTCTCTAGCGTTACTGAAGAAATCATTTCAAAAAAACAAGAAGAATT	ACAGAGCAAAGAAACCAAAGAGGGTAAGCATGATGG
AGAAAGGCTCTCTAGCGTTACTGAAGAAATCATTTCAAAAAAACTAGAAGAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017376.1|WP_000051425.1|372814_373048_+|cell-division-topological-specificity-factor-MinE	unknown	unknown	gnl|CDD|188120
NC_017376.1|WP_000599261.1|373851_374256_+|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl|CDD|234639
NC_017376.1|WP_000833979.1|369020_369959_-|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl|CDD|224577
NC_017376.1|WP_000056304.1|383367_384144_+|flagellar-assembly-protein-FliH	unknown	unknown	gnl|CDD|235850
NC_017376.1|WP_001052079.1|387816_388572_+|DUF3883-domain-containing-protein	unknown	unknown	gnl|CDD|379021
NC_017376.1|WP_001117119.1|375602_376484_-|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|223638
NC_017376.1|WP_000603081.1|384140_385997_+|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl|CDD|129308
NC_017376.1|WP_001168319.1|369955_370738_-|NAD+-synthase	unknown	unknown	gnl|CDD|184435
NC_017376.1|WP_000829922.1|379916_380585_+|hypothetical-protein	unknown	unknown	gnl|CDD|239486
NC_017376.1|WP_000742665.1|368545_369088_+|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase	unknown	unknown	gnl|CDD|274661
NC_017376.1|WP_000810807.1|376483_378034_-|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl|CDD|273193
NC_017376.1|WP_001207574.1|370995_371988_+|ketol-acid-reductoisomerase	unknown	unknown	gnl|CDD|235491
NC_017376.1|WP_000373169.1|378042_379659_-|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl|CDD|235437
NC_017376.1|WP_001019089.1|372011_372818_+|septum-site-determining-protein-MinD	unknown	unknown	gnl|CDD|225447
NC_017376.1|WP_000699930.1|374663_374969_+|hypothetical-protein	unknown	unknown	unknown
NC_017376.1|WP_000841123.1|373054_373855_+|DNA-protecting-protein-DprA	unknown	unknown	gnl|CDD|273238
NC_017376.1|WP_080004651.1|374352_374541_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276807
NC_017376.1|WP_000201853.1|382349_383381_+|flagellar-motor-switch-protein-FliG	unknown	unknown	gnl|CDD|272961
NC_017376.1|WP_000364683.1|380628_382332_+|flagellar-basal-body-M-ring-protein-FliF	unknown	unknown	gnl|CDD|129310
NC_017376.1|WP_000660814.1|385993_387802_+|elongation-factor-4	unknown	unknown	gnl|CDD|235462

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017376.1|WP_000051425.1|372814_373048_+|cell-division-topological-specificity-factor-MinE	gnl|CDD|188120	TIGR01215, Cell_division_topological_specificity_factor, cell division topological specificity factor MinE. This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division].	9.5424e-26
NC_017376.1|WP_000599261.1|373851_374256_+|Holliday-junction-resolvase-RuvX	gnl|CDD|234639	PRK00109, PRK00109, Holliday junction resolvase RuvX.	1.26165e-34
NC_017376.1|WP_000833979.1|369020_369959_-|tetraacyldisaccharide-4'-kinase	gnl|CDD|224577	COG1663, LpxK, Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane].	1.89042e-87
NC_017376.1|WP_000056304.1|383367_384144_+|flagellar-assembly-protein-FliH	gnl|CDD|235850	PRK06669, fliH, flagellar assembly protein H; Validated.	1.71714e-64
NC_017376.1|WP_001052079.1|387816_388572_+|DUF3883-domain-containing-protein	gnl|CDD|379021	pfam13020, DUF3883, Domain of unknown function (DUF3883). This is a domain is uncharacterized. It is found on restriction endonucleases.	1.48876e-15
NC_017376.1|WP_000810807.1|376483_378034_-|single-stranded-DNA-specific-exonuclease-RecJ	gnl|CDD|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_017376.1|WP_000603081.1|384140_385997_+|1-deoxy-D-xylulose-5-phosphate-synthase	gnl|CDD|129308	TIGR00204, 1-deoxy-D-xylulose-5-phosphate_synthase, 1-deoxy-D-xylulose-5-phosphate synthase. DXP synthase is a thiamine diphosphate-dependent enzyme related to transketolase and the pyruvate dehydrogenase E1-beta subunit. By an acyloin condensation of pyruvate with glyceraldehyde 3-phosphate, it produces 1-deoxy-D-xylulose 5-phosphate, a precursor of thiamine diphosphate (TPP), pyridoxal phosphate, and the isoprenoid building block isopentenyl diphosphate (IPP). [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine, Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	0
NC_017376.1|WP_001168319.1|369955_370738_-|NAD+-synthase	gnl|CDD|184435	PRK13980, PRK13980, NAD synthetase; Provisional.	5.94766e-122
NC_017376.1|WP_000829922.1|379916_380585_+|hypothetical-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.47481e-11
NC_017376.1|WP_000742665.1|368545_369088_+|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase	gnl|CDD|274661	TIGR03585, PseH, UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase. Sequences in this family are members of the pfam00583 (GNAT) superfamily of acetyltransferases and are proposed to perform a N-acetylation step in the process of pseudaminic acid biosynthesis in Campylobacter species. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci. Significantly, many genomes containing other components of this pathway lack this gene, indicating that some other N-acetyl transferases may be incolved and/or the step is optional, resulting in a non-acetylated pseudaminic acid variant sugar.	2.39608e-60
NC_017376.1|WP_001117119.1|375602_376484_-|RluA-family-pseudouridine-synthase	gnl|CDD|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.93194e-69
NC_017376.1|WP_001207574.1|370995_371988_+|ketol-acid-reductoisomerase	gnl|CDD|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	7.35211e-180
NC_017376.1|WP_000373169.1|378042_379659_-|CTP-synthase-(glutamine-hydrolyzing)	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_017376.1|WP_001019089.1|372011_372818_+|septum-site-determining-protein-MinD	gnl|CDD|225447	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning].	3.57452e-151
NC_017376.1|WP_000841123.1|373054_373855_+|DNA-protecting-protein-DprA	gnl|CDD|273238	TIGR00732, Protein_smf, DNA protecting protein DprA. Disruption of this gene in both Haemophilus influenzae and Helicobacter pylori drastically reduces the efficiency of transformation with exogenous DNA, but with different levels of effect on chromosomal (linear) and plasmid (circular) DNA. This difference suggests the DprA is not active in recombination, and it has been shown not to affect DNA binding, leaving the intermediate step in natural transformation, DNA processing. In Strep. pneumoniae, inactivation of dprA had no effect on the uptake of DNA. All of these data indicated that DprA is required at a later stage in transformation. Subsequently DprA and RecA were both shown in S. pneumoniae to be required to protect incoming ssDNA from immediate degradation. Role of DprA in non-transformable species is not known. The gene symbol smf was assigned in E. coli, but without assignment of function. [Cellular processes, DNA transformation].	5.48924e-95
NC_017376.1|WP_080004651.1|374352_374541_+|tetratricopeptide-repeat-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	0.00065307
NC_017376.1|WP_000201853.1|382349_383381_+|flagellar-motor-switch-protein-FliG	gnl|CDD|272961	TIGR00207, Flagellar_motor_switch_protein_FliG, flagellar motor switch protein FliG. The fliG protein along with fliM and fliN interact to form the switch complex of the bacterial flagellar motor located at the base of the basal body. This complex interacts with chemotaxis proteins (eg CHEY). In addition the complex interacts with other components of the motor that determine the direction of flagellar rotation. The model contains putative members of the fliG family at scores of less than 100 from Agrobacterium radiobacter and Sinorhizobium meliloti as well as fliG-like genes from treponema pallidum and Borrelia burgdorferi. That is why the suggested cutoff is set at 20 but was set at 100 to construct the family. [Cellular processes, Chemotaxis and motility].	6.16419e-166
NC_017376.1|WP_000364683.1|380628_382332_+|flagellar-basal-body-M-ring-protein-FliF	gnl|CDD|129310	TIGR00206, Flagellar_M-ring_protein, flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF). Component of the M (cytoplasmic associated) ring, one of four rings (L,P,S,M) which make up the flagellar hook-basal body which is a major portion of the flagellar organelle. Although the basic structure of the flagella appears to be similar for all bacteria, additional rings and structures surrounding the basal body have been observed for some bacteria (eg Vibrio cholerae and Treponema pallidum). [Cellular processes, Chemotaxis and motility].	0
NC_017376.1|WP_000660814.1|385993_387802_+|elongation-factor-4	gnl|CDD|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0

Protein sequences

>NC_017376.1|WP_000699930.1|374663_374969_+|hypothetical-protein
MKIMHQVRDFLDSCKQTIQKNSNEIFQKTKRALFKEESQKIREQVVKIVEKCLKEKGMKLSDFNEEELKIMFEAEEKRLLEQIQTKHFKEVWEKGENEQGK
>NC_017376.1|WP_080004651.1|374352_374541_+|tetratricopeptide-repeat-protein
MLVLCVDWGGGLMAEPNHEELFNLGMLSYDKQDFSKARKYFEKACKPGDKEACDDLYQLLEI
>NC_017376.1|WP_000599261.1|373851_374256_+|Holliday-junction-resolvase-RuvX
MILACDVGLKRIGIAVLLNGVILPLEAILRRNRNQASKDLSDLLREKNIQVLVVGKPNESYTDTNARIEHFIKLVDFKGEIVFINEDRSSIETYENLEHLSKKNKRLAIKDGRLDSLSACRILERYYQQVLKKR
>NC_017376.1|WP_000841123.1|373054_373855_+|DNA-protecting-protein-DprA
MKSNFQYSALENIPKVFDILKDPPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGVDIIAQENALPKTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPVKGSFLARNRLVIALSDAVIIPQADLKSGSMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDHHLKEMPEMKDEFLEYCAKNPSYEEAYLKFGDKLLEYELLGKIKRINHIVVLA
>NC_017376.1|WP_000051425.1|372814_373048_+|cell-division-topological-specificity-factor-MinE
MSLFDFFKNKGSATTATDRLKLILAKERTLNLPYMEEMRKEIIAVIQKYTKSSDIHFKTLDSNQSVETIEVEIILPK
>NC_017376.1|WP_001019089.1|372011_372818_+|septum-site-determining-protein-MinD
MAIVVTITSGKGGVGKSTTTANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKTKNLSFLAASQSKDKNILDREKVAILINALRADFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIIDAKSNRAKRGEEVHKHLIINRLKPELVANGEMISIEEVLKILCLPLIGIIPEDHHIISATNKGEPVIRTDCESAKAYQRITRRILGEEVEYVEFKAKRGFFSALKGIFS
>NC_017376.1|WP_001207574.1|370995_371988_+|ketol-acid-reductoisomerase
MALPIYYDKDIDLGVIQSLQVGVIGYGAQGEAQALNLRDSKVRVRIGLYQGSLSVSKAKKEGFEVLGVKELVQQSDVIMALLPDELHKEVLEKEVIPFLKEGQIVGFAHGFSVHFNQVVLPKGVGAILVAPKGPGSALREEYLKNKGLYHLIAIEQESSKYNAKAVALSYAKAMGGGRMGVLETSFKEECESDLFGEQAVLCGGLEAIVRMGFETLIKAGYPEELAYFECVHEVKLVADLLHYKGVEGLRKHISNTAEFGAIKNREPMGNLLKKRMQKILKKIQNGSFAKDFLLEKSLNYPRLNTERKALKETKIEQIGEILRTPFNHKK
>NC_017376.1|WP_001168319.1|369955_370738_-|NAD+-synthase
MQKDYQKLIVYLCDFLEKEVQKRGFKKVVYGLSGGLDSAVVGVLCQKVFKENAHALLMPSSVSMPESKTDALNLCEKFSIPYTEYSIAPYDALFGSHFKDASLTRKGNFCARLRMAFLYDYSLKSDSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELACYLNIPKKILNKPPSADLFMGQSDEKDLGYPYSVIDPLLKDIEALFKNKPIDAETLAHLGYDRALIKNIISRIQKNAFKLESPAIAQQFNPK
>NC_017376.1|WP_000833979.1|369020_369959_-|tetraacyldisaccharide-4'-kinase
MKSDKPFLERYFYDPTLLQKGLIFVLYPFSLIYQGTATLKRKMAKKHDFKIPLISVGNLIAGGSGKTPFILETAPRYQEVAVVSRGYQRDSKGLVVVSVKGNILVSQKTAGDEAYLLALNLKQASVIVSEKRDLGVLKALELGAKIVFLDDGFRFNFNQFNLLLKPKIPPYYPFCLPSGLYRESIKSYKEAHLVITEDKDYQRITSISHPTKRMLLVTAIANPSRLDAFLPKEVVKKLYFKDHAPFDLELLEKEFYQNNAASLLVTPKDLVKLQDCNLPLSVLDLKLEIDPKILERIDRYILSYPCNTKERL
>NC_017376.1|WP_000742665.1|368545_369088_+|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase
MKKNYSYGNIQAVDFTHLNDEEKLLVLEFRNHPNTALWMYSAFISLKTHLQFIEDLKNSPNHRYFLFKEEGVYLGVGSITKINFFHKHGYLGIYKNPFLKNGGETILKALERIAFEEFQLNSLHLEVMENNFKAIAFYEKNHYELEGRLKGFISKEKEFIDVLLYYKDKKGYNDQFSLKS
>NC_017376.1|WP_001117119.1|375602_376484_-|RluA-family-pseudouridine-synthase
MPFVEEEFEILKPTKALFFVRDVLKCSLKEAQRHLDKQRLKHNQQAVRKSQMIQGIVSLIHFKPNEKTQALVFETKDFGVFDKPAQVYTHPKGYFYHESLLDCIQSHLGKNAHPAHRLDYETSGLVLAGKTLQSTKDLKALFMQKKVKKTYLALAHGLVEKSMKIDKPILTPQNIQKDLRIRSKISPLGKPSITLVEPLSYNPFLDISLLKITPLTGRTHQIRLHLSSIGHRIVGERLYGVADEEAREYLQLKRENNAPLLMLHAFRLGFEFKGAIYEITSPMPQRFMPFLKD
>NC_017376.1|WP_000810807.1|376483_378034_-|single-stranded-DNA-specific-exonuclease-RecJ
MKQKLKAQIKERVVSIAYNEKGFPSPFLFKDLKKAVLKIIEAMRANTEILVVGDYDADGVISSTIMAKFFESLNYKHVRIVIPNRFIDGYGISKKFLEKHHAPLIITVDNGISAFEAARFCKEKNYTLIITDHHCLHHDEVPDAYAVINPKQPDCDFIQKEVCGALVAFYLCYGIHQLLGKEKSHSSELLCLAGVATIADMMPLTFFNRFLVSKALYFLQKESLGAMGFLRQREIFRKRSLKASDISFSIAPLINSAGRMQDAKMALDFLSANNFQDGYSLYERLKACNMKRKMIQQQVFEEAFKHAMVGEKIIVAFKDNWHEGVLGIVASKLVEATQKPSLVFTFKEGVYKGSARSSSNIDLIDALNGVSSLLLGYGGHRQACGLSVGKNNLISLFETLENFDFKVLPFCEKEPPLTLKLKDIDRELLEIIETGEPYGQENPEPLFQAQNLEVIEEKIIKESHQVLRFKDKECVKEAIYFNTERFLKAGEKVSAIFSVELDEYSNEPKMFVKSLL
>NC_017376.1|WP_000373169.1|378042_379659_-|CTP-synthase-(glutamine-hydrolyzing)
MDRAKFIFVTGGVLSSLGKGISSSSIATLLQHCNYQVSILKIDPYINIDPGTMSPLEHGEVFVTSDGAETDLDIGHYERFLNRNLTRLNNFTTGQIFSSVIEKERKGEYLGKTIQIVPHVTDEIKRRIKSAAKGLDFLIVEVGGTVGDMEGMFYLEAIRQLKLELGNEKVINVHVTLIPYIQTTNELKTKPTQHSVQELRRLGVTPQIILARSPKPLDKELKNKIALSCDVEQDSVIVATDTKSIYACPILFLQEGILTPIARRFNLNKLHPKMAAWNTLVEKIIAPKHKVRVGFVGKYLSLKESYKSLIEALIHAGAHLDTQVNIEWLDSENFNEKTDLEGVDAILVPGGFGERGIEGKICAIQRARLEKLPFLGICLGMQLAIVEFCRNVLGLKGANSTEFNQRCEYPVVYLIGDFMDQNHQKQVRTYNSPLGGTMRLGEYECEIVPNSLLEKAYKKPSIKERHRHRYEINPKYRQEWENKGLKVVGFGANHLIEAIELEDHPFFVGVQFHPEFTSRLQSPNPIILDFIKSALHKS
>NC_017376.1|WP_000829922.1|379916_380585_+|hypothetical-protein
MAENSFKNVSTQPKVFFLLPAKTLFLLGGIFSAFFILIVGLVFFDHAHLMDNAIFNFARSTPFNSSPILTLILQNTARLGSSQFVLPLSLLVGVFLSLYRRNLTLGVWFVLSVILFEALLESLKHLLAHSIQWLSRNANFPNATALSLTLFYGLLVLLIPHLITHQTLKNVLFYSLFGLIFLIGLVLILLGVSFSSVLGGFCLGALGACFSIGIYLSVFQKI
>NC_017376.1|WP_000364683.1|380628_382332_+|flagellar-basal-body-M-ring-protein-FliF
MDLKVLLQRIVDFFIKLNKKQKIALIAAGVLITALLVFLLLYPFKEKDYAQGGYGVLFEGLDSSDNALILQHLQQNQIPYKVSKDDTILIPKDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFDQNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKIKPDMKLSPTQILGIKNLIAAAVPKLTIDNVKIVNENGESIGEGDILENSKELALEQLHYKQNFENILENKIVNILAPIVGGKNKVVARVNAEFDFSQKKSTKETFDPNNVVRSEQNLEEKKEGASKKQVGGVPGVVSNIGPVQGLKDNKEPEKYEKSQNTTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIALKDGANTLEYEPLSDESLQKINALVKQAIGYNQNRGDDVAVSNFEFNPMAPMIDNATLSEKIMHKTQKILGSFTPLIKYVLVFIVLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNATFSEEEVRYEIILEKIRGTLKERPDEIATLFKLLIKDEISSDGAKG
>NC_017376.1|WP_000201853.1|382349_383381_+|flagellar-motor-switch-protein-FliG
MATKLTPKQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQIGAAVLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEAKKVMDKLTKSLQTQKNFAYLGKIKPQQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRVSTVLENKLESLTSYKIEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMFTFEDIVKLDNFAIREILKVADKKDLSLALKTSTKDLTDKFLNNMSSRAAEQFVEEMQYLGAVKIKDVDVAQRKIIEIVQSLQEKGVIQTGEEEDVIE
>NC_017376.1|WP_000056304.1|383367_384144_+|flagellar-assembly-protein-FliH
MSLNSRKNLIQKDHLNKHDIQKYEFKSMANLPPKTNSNGASLETPNPQEPLEKKAIENDLIDCLLKKTDELSSHLVKLQMQFEKAQEESKALIENAKNDGYKIGFKEGEEKMRNELTHSVNEEKNQLLHAITALDEKMKKSEDHLMALEKELSAIAIDIAKEVILKEVEDNSQKVALALAEELLKNVLDATDIHLKVNPLDYPYLNERLQNASKIKLESNEAISKGGVMITSSNGSLDGNLMERFKTLKESVLENFKV
>NC_017376.1|WP_000603081.1|384140_385997_+|1-deoxy-D-xylulose-5-phosphate-synthase
MILQNKTFDLNPNDIAGLELVCQTLRSRILEVVSANGGHLSSSLGAVELIVSMHALFDCQKNPFIFDTSHQAYAHKLLTGRFESFSTLRQFKGLSGFTKPSESAYDYFIAGHSSTSVSIGVGVAKAFCLKRVLGMPIALLGDGSISAGIFYEALNELGDRKYPMIMILNDNEMSISTPIGALSKALSQLMKGPFYQSFRSKVKKILSTLPESVNYLASRFEESFKLITPGVFFEELGINYIGPINGHDLSAIIETLKLAKELKEPVLIHAQTLKGKGYKIAEGRYEKWHGVGPFDLDTGLSKKSKSAILSPTEAYSNTLLELAKKDEKIVGVTAAMPSGTGLDKLIDAYPLRFFDVAIAEQHALTSSSAMAKEGFKPFVSIYSTFLQRAYDSIVHDACISSLPIKLAIDRAGIVGEDGETHQGLLDVAYLRSIPNMVIFAPRDNETLKNAVRFANEHDSSPCAFRYPRGSFALKEGVFEPSGFVLGQSELLKKEGEILLIGYGNGVGRAHLVQLALKEKNIECALLDLRFLKPLDQNLSAIIAPYQKLYVFSDNYKLGGVASAILEFLSEQNILKPVKSFEIIDEFIMHGNTALVEKSLGLDTESLTDAILKDLGQER
>NC_017376.1|WP_000660814.1|385993_387802_+|elongation-factor-4
MKEKTPMKNIRNFSIIAHIDHGKSTLADCLIAECNAISNREMTSQVMDTMDIEKERGITIKAQSVRLNYTFKGENYILNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANTYIALDNNLEILPVINKIDLPNANVLEVKQDIEDTIGIDCSNANEVSAKAKLGIKDLLEKIITTIPAPSGDFNAPLKALIYDSWFDNYLGALALVRIMDGSINTEQEILVMGTGKKHGVLGLYYPNPLKKIPTKSLECGEIGIVSLGLKSVTDIAVGDTLTDAKNPTPKPIEGFMPAKPFVFAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFGFRVGFLGLLHMEVIKERLEREFGLNLIATAPTVVYEVHLTDNSIKYVQNPSELPPENHIACIKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDKLKSCTKGYASFDYEPIENREAHLVKLDVRVAGDVVDALSIIIDKNKAYEKGRALVETMKELIPRQLFEVAIQASVGNKIIARETIKSVGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVELPQEAFLAILKID
>NC_017376.1|WP_001052079.1|387816_388572_+|DUF3883-domain-containing-protein
MAKHKNYEILNLIGYALAKFDNDFIKEFGFSTKNAFFEYCVQIGLADTTGVIKNRMDLFDYFFPNKRKGWWQKGDAYIHRKLWIDSLFKDEDAKGFSHIVKLFLQEQYGIQLDITPNAYLKTRYKSMQETGLEAELYFLNHYKNIKIFSCGRLKDMRLFGDGYDFYIQTNKQGFLVEVKGIREKQGTLRLTQKEYEQAQTYSHDYVLVVVLNLSEKPHLLSIANPLKHLEFKACERKQKSILEYHLIGQIK

Crispr_ID: NC_017376_2

• CRISPR_ID: NC_017376_2
• CRISPR_location: 972795-972994
• CRISPR_type: Orphan
• Repeat_type: I-B
• Spacer_info: 3 spacers

Consensus repeat of NC_017376_2

Consensus_repeat	Method
CTTCAATCAAGGGACTTATAATTTTAATA	CRT
TTCAATCAAGGGACTTATCATTTTAAT	CRISPRCasFinder

spacers of NC_017376_2

>2.1|972824|31|NC_017376|CRT
ACAGCGCCACTTTAAGCTCCAATCATAGCGC
>2.2|972884|28|NC_017376|CRT
GTGCTCAATCTGCTTTTGAAAACAGCAG
>2.3|972941|25|NC_017376|CRT
GTAACGCCAGCTTCAATAACGACAC
>2.4|972823|33|NC_017376|CRISPRCasFinder
AACAGCGCCACTTTAAGCTCCAATCATAGCGCT
>2.5|972883|30|NC_017376|CRISPRCasFinder
AGTGCTCAATCTGCTTTTGAAAACAGCAGC
>2.6|972940|27|NC_017376|CRISPRCasFinder
GGTAACGCCAGCTTCAATAACGACACC

CRISPR arrays and Neighbor proteins around NC_017376_2

CRISPR arrays

The CRISPR arrays of NC_017376_2

>merge|NC_017376|2|972795-972994|CRT,CRISPRCasFinder
CTTCAATCAAGGGATTTACAATTTTAGTAACAGCGCCACTTTAAGCTCCAATCATAGCGCTTTCAATCAAGGGACTTATCATTTTAATAGTGCTCAATCTGCTTTTGAAAACAGCAGCTTCAATCAAGGGACTTATAATTTTAATGGTAACGCCAGCTTCAATAACGACACCTTCAATCAAGGGACTTATAGCTTTAATA

>NC_017376|2|1|972795-972994|CRT
CTTCAATCAAGGGATTTACAATTTTAGTA	ACAGCGCCACTTTAAGCTCCAATCATAGCGC
TTTCAATCAAGGGACTTATCATTTTAATA	GTGCTCAATCTGCTTTTGAAAACAGCAG
CTTCAATCAAGGGACTTATAATTTTAATG	GTAACGCCAGCTTCAATAACGACAC
CTTCAATCAAGGGACTTATAGCTTTAATA

>NC_017376|2|2|972796-972993|CRISPRCasFinder
TTCAATCAAGGGATTTACAATTTTAGT	AACAGCGCCACTTTAAGCTCCAATCATAGCGCT
TTCAATCAAGGGACTTATCATTTTAAT	AGTGCTCAATCTGCTTTTGAAAACAGCAGC
TTCAATCAAGGGACTTATAATTTTAAT	GGTAACGCCAGCTTCAATAACGACACC
TTCAATCAAGGGACTTATAGCTTTAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017376.1|WP_000894506.1|955355_957383_+|ATP-dependent-helicase	unknown	unknown	gnl|CDD|223288
NC_017376.1|WP_080004674.1|982433_983414_+|zinc-metalloprotease-HtpX	unknown	unknown	gnl|CDD|235081
NC_017376.1|WP_001240221.1|970101_970794_-|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl|CDD|198414
NC_017376.1|WP_001052437.1|981349_982495_+|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl|CDD|272903
NC_017376.1|WP_000041788.1|985680_986340_+|hypothetical-protein	unknown	unknown	unknown
NC_017376.1|WP_000688648.1|970937_971936_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|273675
NC_017376.1|WP_001248509.1|961917_963462_-|outer-membrane-beta-barrel-protein-HofG	unknown	unknown	gnl|CDD|334957
NC_017376.1|WP_001126052.1|966756_970014_-|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl|CDD|235393
NC_017376.1|WP_001160303.1|979242_980352_+|Hop-family-outer-membrane-protein-HopJ/HopK	unknown	unknown	gnl|CDD|280099
NC_017376.1|WP_000070347.1|983972_984884_+|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|223220
NC_017376.1|WP_080004705.1|954213_955362_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|223897
NC_017376.1|WP_000998465.1|963708_966150_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|273808
NC_017376.1|WP_000426949.1|983414_983957_+|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl|CDD|129173
NC_017376.1|WP_001128389.1|980417_980624_-|4-oxalocrotonate-tautomerase-family-protein	unknown	unknown	gnl|CDD|129125
NC_017376.1|WP_001229972.1|966320_966752_-|hypothetical-protein	unknown	unknown	gnl|CDD|376519
NC_017376.1|WP_001099596.1|980771_981353_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|273176
NC_017376.1|WP_000812553.1|959511_961101_+|Hop-family-adhesin-AlpB	unknown	unknown	gnl|CDD|280099
NC_017376.1|WP_000592453.1|957930_959490_+|Hop-family-adhesin-AlpA	unknown	unknown	gnl|CDD|280099
NC_017376.1|WP_000236873.1|986341_986944_+|6-pyruvoyl-tetrahydropterin-synthase-family-protein	unknown	unknown	gnl|CDD|223792
NC_017376.1|WP_000722448.1|984880_985684_+|5'/3'-nucleotidase-SurE	unknown	unknown	gnl|CDD|234732

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017376.1|WP_000894506.1|955355_957383_+|ATP-dependent-helicase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	2.49057e-135
NC_017376.1|WP_080004674.1|982433_983414_+|zinc-metalloprotease-HtpX	gnl|CDD|235081	PRK02870, PRK02870, heat shock protein HtpX; Provisional.	0
NC_017376.1|WP_001240221.1|970101_970794_-|Bax-inhibitor-1/YccA-family-protein	gnl|CDD|198414	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins. This family is comprised of bacterial relatives of the mammalian members of the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. In plants, BI-1 like proteins play a role in pathogen resistance. A characterized prokaryotic member, Escherichia coli YccA, has been shown to interact with ATP-dependent protease FtsH, which degrades abnormal membrane proteins as part of a quality control mechanism to keep the integrity of biological membranes.	3.48067e-52
NC_017376.1|WP_001052437.1|981349_982495_+|tRNA-pseudouridine(13)-synthase-TruD	gnl|CDD|272903	TIGR00094, tRNA_pseudouridine_synthase_D, tRNA pseudouridine synthase, TruD family. an EGAD loading error caused one member to be called surE, but that's an adjacent gene. MJ11364 is a strong partial match from 50 to 230 aa. [Protein synthesis, tRNA and rRNA base modification].	3.60308e-141
NC_017376.1|WP_000688648.1|970937_971936_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	1.43202e-157
NC_017376.1|WP_001248509.1|961917_963462_-|outer-membrane-beta-barrel-protein-HofG	gnl|CDD|334957	pfam02521, HP_OMP_2, Putative outer membrane protein. This family consists of putative outer membrane proteins from Helicobacter pylori (campylobacter pylori).	1.50063e-178
NC_017376.1|WP_001126052.1|966756_970014_-|carbamoyl-phosphate-synthase-large-subunit	gnl|CDD|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NC_017376.1|WP_001160303.1|979242_980352_+|Hop-family-outer-membrane-protein-HopJ/HopK	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	2.85561e-47
NC_017376.1|WP_000070347.1|983972_984884_+|polyprenyl-synthetase-family-protein	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.00228e-74
NC_017376.1|WP_080004705.1|954213_955362_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	1.22039e-52
NC_017376.1|WP_000998465.1|963708_966150_-|TonB-dependent-receptor	gnl|CDD|273808	TIGR01786, hemoglobin-haptoglobin-binding_protein, TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein. This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	5.25801e-46
NC_017376.1|WP_000426949.1|983414_983957_+|GTP-cyclohydrolase-I-FolE	gnl|CDD|129173	TIGR00063, GTP_cyclohydrolase_1, GTP cyclohydrolase I. alternate names: Punch (Drosophila),GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate in prokaryotes, of tetrahydrobiopterin in vertebrates, and of pteridine-containing pigments in insects. [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	1.19934e-105
NC_017376.1|WP_001128389.1|980417_980624_-|4-oxalocrotonate-tautomerase-family-protein	gnl|CDD|129125	TIGR00013, Probable_tautomerase_K2, 4-oxalocrotonate tautomerase family enzyme. 4-oxalocrotonate tautomerase is a homohexamer in which each monomer is very small, at about 62 amino acids. Pro-1 of the mature protein serves as a general base. The enzyme functions in meta-cleavage pathways of aromatic hydrocarbon catabolism. Because several Arg residues located near the active site in the crystal structure of Pseudomonas putida are not conserved among all members of this family, because the literature describes a general role in the isomerization of beta,gamma-unsaturated enones to their alpha,beta-isomers, and because of the presence of fairly distantly related paralogs in Campylobacter jejuni, the family is regarded as not necessarily uniform in function. [Energy metabolism, Other].	2.56644e-24
NC_017376.1|WP_001229972.1|966320_966752_-|hypothetical-protein	gnl|CDD|376519	pfam01300, Sua5_yciO_yrdC, Telomere recombination. This domain has been shown to bind preferentially to dsRNA. The domain is found in SUA5 as well as HypF and YrdC. It has also been shown to be required for telomere recombniation in yeast.	0.000333464
NC_017376.1|WP_001099596.1|980771_981353_+|recombination-protein-RecR	gnl|CDD|273176	TIGR00615, Recombination_protein_RecR, recombination protein RecR. All proteins in this family for which functions are known are involved in the initiation of recombination and recombinational repair. RecF is also required. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	1.72604e-98
NC_017376.1|WP_000812553.1|959511_961101_+|Hop-family-adhesin-AlpB	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	1.61717e-53
NC_017376.1|WP_000592453.1|957930_959490_+|Hop-family-adhesin-AlpA	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	6.53186e-55
NC_017376.1|WP_000236873.1|986341_986944_+|6-pyruvoyl-tetrahydropterin-synthase-family-protein	gnl|CDD|223792	COG0720, COG0720, 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism].	2.17651e-20
NC_017376.1|WP_000722448.1|984880_985684_+|5'/3'-nucleotidase-SurE	gnl|CDD|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	5.23927e-126

Protein sequences

>NC_017376.1|WP_000688648.1|970937_971936_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MKIFINGFGRIGRCVLRAILERSDTNPHLEVIGINDPVNWEILAYLLEHDSTHGLLHKEARYSNGKLIIGSLEIPVFNSIKDLKGVDVILECSGKFLEPKVLENYLLLGAKKVLLSAPFIGEYDEKQYPTLVYGVNHFLYQNQAIVSNASCTTNAIAPICSILDKAFNIKEGMLTTIHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSMIDLSLFLEKKASKDPINDLLIEASKGALKGVLEIDLKERVSSDFISNPSSVIIAPDLTFTLENMVKIMGWYDNEWGYSHRLVDMAQFVYHY
>NC_017376.1|WP_001240221.1|970101_970794_-|Bax-inhibitor-1/YccA-family-protein
MALYDRADSRNAYAEDSLLHESELVGFVKTTYKFFAGSLLLATIGALLGLMNFQAVVQYKWVFFIAEIAAFFGLMFSKSKPGLNLFMLFAFTSLSGVTLVPLLGMVIAKAGLGAIWQALGMTTIVFGLMSVYALKTKNDLANMGKMLFIALIVVLVCSLINLFLGSPMFQVVIAGASAILFSLYIAYDTQNIVKGMYDSPIDAAVSLYLDFLNVFISILQIIGIFSDRDK
>NC_017376.1|WP_001126052.1|966756_970014_-|carbamoyl-phosphate-synthase-large-subunit
MPKRADISNILLIGSGPIVIGQACEFDYSGTQSCKTLKSLGYRVILINSNPATVMTDPEFSHQTYIQPITPENIAAIIKKEKIDAILPTMGGQTALNAVMQMHQKGMLEGVELLGAKIEAIKKGEDRQAFKEAMLKIGMDLPKGRYAYNELEALEAINEIGFPAIIRASFTLAGGGSGVAYNIEEFQELAKNALDASPINEILIEESLLGWKEYEMEVIRDSKDNCIIVCCIENIDPMGVHTGDSITIAPSLTLTDKEYQRMRDASFAILREIGVDTGGSNVQFAIHPETLRMVVIEMNPRVSRSSALASKATGFPIAKVATMLAVGFSLDEIKNDITNTPASFEPSLDYIVVKIPRFAFEKFAGVSSTLGTSMKSIGEVMAIGGNFLEALQKALCSLENNWLGFESLSKDLEAIKKEIRRPNPKRLLYIADAFRLGVSVDEVFELCQIDRWFLSQIQKLVKAEEGINSSVLTDAKKLRGLKNLGFSDARIAAKIKENENLEVSPFEVELARSNLQIAPHFEEVDTCAAEFLSLTPYLYSTYAPNPLPPIENKQEKQEKKILIIGSGPNRIGQGIEFDYCCVHASFALKDLNIKSVMLNCNPETVSTDYDTSDTLYFEPIHFECVKSIIQRERVDGIIVHFGGQTPLKLAKDLAKMQAPIIGTPFKVIDIAEDREKFSLFLKELDIKQPENGMAKSVDEAYSIANVIGFPIIVRPSYVLGGQHMQILENIEELRHYLESVTHSLEISPKNPLLIDKFLEKAVELDVDAICDKKEVYIAGILQHIEEAGIHSGDSACFIPSTLNPEILDEIERVSAKIALHLGVVGLLNIQFAVYENSLYLIEVNPRASRTVPFLSKALGVPLAKVATRVMVLEDLKEALKFYDKKNIVEYSKGVYKPKMPHFVALKEAVFPFNKLYGSDLILGPEMKSTGEVMGIARSLGLAFFKAQTACFNPIKNKGLIFASIKDKDKEEACVLMKRLVQLGFELCATEGTHKALEKAGVKSLKVLKISEGRPNIMDLMMNGEISMAINTSDHKSQDDAKLIRASVLKNHVSYFTTLSAIEVLLLALEESSKEDELLALQDYLK
>NC_017376.1|WP_001229972.1|966320_966752_-|hypothetical-protein
MALVYLAQSDTTIGLLSKDSEKLNALKNRPKNQSVLIESADFTTLKSLVRAPNAFKNFIRRSLKTTFIYPNSKAVRVVRGRHGDFLKRFKTLYSTSANLTQCAYDKEIASNLADVIVSDERGLFESASSKIFKLYKNKKVRVR
>NC_017376.1|WP_000998465.1|963708_966150_-|TonB-dependent-receptor
MNDKRFRKYWSFSIFLSLLGMFELEAKEEEKEERKTERKKDKKKNAQHTLGKVTTQAAKIFNYNNQTTISSKELERRQANQIGDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGAAQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALIGAIKMETKSASDFIPKGKDYAISGAATFLTNFGDRETVMGAYRNHHFDALLYYTHQNIFYYRDGDNAMKNLFDPKAENKVTGSPSEQNNVMAKINGYLSERDTLTLSYNMTRDNANRPLRANFTGTFLPYSCGDFNAFPNEKNPSDCLFENDASLFKTYSVNLVHNVSLNYEREGGSRFGDPKLKINGYTSIRNVQIDPLFRPSDIATIIPFTPNPKLGEENECVAQGGIYDALKQTCSITFKSLGGGSVVANKNLFIINSGFNANVIHTIDHKNDNLLEYGLNYQNLTTFDKAIPNSELVKPGDAPDACLRVTGPNDPNMNGRCQRNGATANVVGVYAQANYTLHPMITLGAGTRYDVYTLVDKDWQLHITQGFSPSAALNVSPLENLNFRLSYAYVTRGPMPGGLVWMRQDNLRYNRNLKPEIGQNVEFNTEYSSQYFDFRAAGFVQLISNYINQFSSTLFVTNLPAQDIIYVPGYEVSGTAKYKGFSLGLSVARSWPSLKGRLIADVYELAATTGNVFILTASYKIPRTGLSITWLSRFVTDLSYCSYSPYRNGPTDIDRRPSDCPKTPGIFHVHKPGYGVSSFFITYKPTYKKLKGLSLNAVFNNVFNQQYIDQASPVMSPDEPNQDKYARGMAEPGFNARFEISYKF
>NC_017376.1|WP_001248509.1|961917_963462_-|outer-membrane-beta-barrel-protein-HofG
MRQEKYFLTSSLSLLSFLLCPVEAFDYRFSGRVENFSKIGFNNSQINTKKGIYPTESFIDIVTLAQVKVNLLPKGTENHRLSVSLGGAIAAIPYDKTKNDINQANGKIFGSIVENFIGGYHGYFFNKYLGPAYAGTSQSASYHARPYVVDTAFLKYDYKDVFGFKAGRYEANIDFMSGSNQGWEVYYQPYKTETQRLRFWWWSSFGRGLAFNSWIYEFFATVPYLKKGGNPNNSNDFINYGWHGITTTYSYKGLDAQFFYYFAPKTYNAPGFKLVYDTNRNFENVGFRSQSMIMTTFPLYYRGWYNPETNTYSLEDSTPHGSLLGRNGVTLNIRQVFWWDNFNWSIGFYNTFGNSDAFLGSHTMPRGNNTSYIANEISVTTRHAGMIGYDFWDNTAYDGLADAITNANTFTFYTSVGGIHKRFAWHVFGRVSHANKNALGQVGRANEYSLQFNASYAFTESVLLNFRITYYGARINKGYQAGYFGAPKFNNPDGDFSANYQDRSYMMTNLTLKF
>NC_017376.1|WP_000812553.1|959511_961101_+|Hop-family-adhesin-AlpB
MKQNLKPFKMIKENLMTQSQKVRFLAPLSLALSLSFNPVGAEEDGGFMTFGYELGQVVQQVKNPGKIKAEELAGLLNSSTTNNTNINIAGTGGNVAGTLGNLFMNQLGNLIDLYPTLNTSNIHQCGATNSGGSSGATTAATTSNSPCFQGNLSLYNEMVGSIKTLSQNLKNNIFQGNNNTTSQNLSNQLSELNTASVYLTYMNSFLNANNQAGGIFQNHTNQAYGNGVTAQQIAYILKQASITMGPSGDSGAAGAFLDAALAQHVFNSANAGNDLSAKEFTSLVQNIVNTSQNALTLANNANISNSTGYQVSYGGNIDQARSTQLLNNTTNTLAKVSALNNELKANPWLGNFAAGNSSQVNAFNGFITKIGYKQFFGENKNVGLRYYGFFSYNGAGVGNGPTYNQVNLLTYGVGTDVLYNVFSRSFGSRSLNAGFFGGIQLAGDTYISTLRNSPQLASRPTATKFQFLFDVGLRMNFGILKKDLKSHNQHSIEIGVQIPTIYNTYYKAGGAEVKYFRPYSVYWVYGYAF
>NC_017376.1|WP_000592453.1|957930_959490_+|Hop-family-adhesin-AlpA
MIKKNRTLFLSLALCASISYAEDDGGFFTVGYQLGQVMQDVQNPGGAKSDELARELNADVTNNILNNNTGGNVAGALSNAFSQYLYSLLGAYPTKLNGSDVSANALLSGAVGSGTCAAAGTAGSSSLNTQSACTAAGYYWLPSLTDRVLSTIGSQTNYGTNTNFPNMQQQLTYLNAANVFFNAMNKALEAKNRTSSNASGTSGATGSDGQTYSQNAIQYLQGQQNILNNAANLLKQDELLLEAFNSAVAANIGNKEFNSAAFTGLVQGIIDQSQLVYNELTKNTISGSAVDSAGINSNQANAVQGRASQLPNALYNAQVTLDKITALNNQVKSMPYLPQFRAGNSRSTNILNGFYTKIGYKQFFGKKRNIGLRYYGFFSYNGASVGFRSTQNNVGLYTYGVGTDVLYNIFSRSYQNRSVDMGFFSGIQLAGETFQSTLRDDPNVKLHGKINNTHFQFLFDFGMRMNFGKLDGKSNRHNQHTVEFGVVVPTIYNTYYKSAGTTVKYFRPYSVYWSYGYSF
>NC_017376.1|WP_000894506.1|955355_957383_+|ATP-dependent-helicase
MLETLPLNPEQKKAASALKGYNLVIASAGTGKTSTIVGRILYLLDNGIKPEEILLLTFTNKASNEMIARVAKYSKLSSKIEAGTFHAVAYRYLKEHYPNLSLKQPKELRKLLESIVDTKNAIDDDKKPYTPQHLYALYSLYTNALKQEDFSAWLSHKNPEHTPYAAFYENILEEFENTKKKHNYIDYNDLLLLFKQAMLERPSPYKEVLCDEFQDTNPLQESILDAINPPSLFCVGDYDQSIYAFNGADISIISNFTQKYQNARVFTLTKNYRSSKEILDLANQVIQRNERIYPKNLEVVKSGHFNKPALLNYNDNIAQCQDIAKRIVMRKNFKEVAVIFRNNASADQLEAALRSYNVPSKRKGSASFFESKEVALALDICALIFNPKDIMAAIHVLSCISDIGSNTAKDIHEALMLLGNGDLKSALIQPNKEAKIYTKKKEITSMGLFEEIFALENSSRFNGVIDKAFHSHPVLMHPKISLNGAKMLSDFFILYTKAPTHSPSALIKHILESAFFQTFKTRLLKERSKNKDGSYNEFKKLQAQKRFNEKMDLLSSLAKNYQNLGRFLNGTLIGSSEATQGCGVNLLSVHASKGLEFKDVYIIDLMEGRFPNHKLMNTGGGIEEERRLFYVAITRAKENLWLSYAKNELRENAKPKEHKPSVFLYEAGLLKPDLK
>NC_017376.1|WP_080004705.1|954213_955362_+|class-I-SAM-dependent-methyltransferase
MNNLDIKTLGQVFTPKKIVDFMLTLKHNQGNVLEPSAGDGSFLRRLKKAVGIEIDPKICPKNALCMDFFDYPLENQFDTIIGNPPYVKHKDIVPSTKDKLNYSLFDERSNLYLFFIEKAIKHLKPKGELIFITPRDFLKSTSSVKLNEWIYKEGTITHFFELGDQKVFPNAMPNCVIFRFCKGNFSRITNDGLQFLCKKGILYFLNQSYTQKLSEVFQVKVGAVSGCDKIFKNEKYGNLEFVTSITKRTHVLEKMVFVNEPNDYLLQHKDSLMQRKIKKFNESNWFEWGRMHHISPKKRIYVNAKTRQKNPFFIHQCPNYDGSILALFPYNQNLDLQNLCDKLNAINWQELGFVCDGRFLFSQRSLENALLPKDFLNEGKTC
>NC_017376.1|WP_001160303.1|979242_980352_+|Hop-family-outer-membrane-protein-HopJ/HopK
MQFPKTLLHSSFFLPLFLSFCIAEENGAYASVGFEYSISHAIQHNDPFLNQERIRIISNAQNKIYKLNQIKNEITSMPNTFNYINNALKNNSKLTPTEMQAEKYYLQSTFQNIEKIMVLSGGVSSNPQLAQALEKMQEPTTNPLEFEENLRNLEAQFTQSQNRMLSSLSSQTAAISNSLNALDPNSYSKNISSMYGVSLSVGYKHFFTKKKNQGFRYYLFYDYGYTNFGFVGNGFDGLGKMNNHLYGLGIDYLYNFIDNAKKHSSVGFYVGFALAGSSWVGSGLGMWVSQTDFINNYLTNYQAKMHTSFFQIPLNFGVRVNVNRHNGFEMGLKIPLAVNSFYETHGKGLNTSLFFKRLVMFNVSYVYSF
>NC_017376.1|WP_001128389.1|980417_980624_-|4-oxalocrotonate-tautomerase-family-protein
MPLINIKLVPENGGPTNEQKQQLIEGVSELMVKVLNKNKASVVVIIDEVDPNNYGLGGESVHHLRQKN
>NC_017376.1|WP_001099596.1|980771_981353_+|recombination-protein-RecR
MNTYKNSLNHFLNLVDCLEKIPNVGKKSAFKMAYHLGLENPYLALKITHALENALENLKTCASCNALSESEVCEICSDESRQNSQICMVLHPRDVFILEDLKDFLGRYYVLNSIEEVDFNALEKRLIEENIKEIIFAFPPTLANDSLMLYIEDKLQHFHLTFTKIAQGVPTGVNFENIDSVSLSRAFNSRIKA
>NC_017376.1|WP_001052437.1|981349_982495_+|tRNA-pseudouridine(13)-synthase-TruD
MNLNFMPLLHAYNHASIDFHFNSSTRDFCVHEVPLYEWSNTGEHAVIQVRKSGLSTLEMLQIFSQILGVKIAELGYAGLKDKNALTTQFISLPKKYAPLLEKSTSNFQERNLKILSLNYHHNKIKLGHLKGNRFFMRFKKMTPLNAQKTKQVLEQIAQFGMPNYFGSQRFGKFNDNHQEGLKILQNQTKFAHQKLNAFLISSYQSYLFNALLSKRLEISKIISAFSLKENLEFFKQKNLNINSNTLKALKNQAHPFKILEGDVMCHYPYGKFFDALELEKEGERFLKKEAVPTGLLDGKKALYAKNLSLEIEKEFQHNLLSSHAKTLGSRRFFWVFVENVTSQYIKEKAQFELGFYLPKGSYASALLKEIKHEKGENNDEF
>NC_017376.1|WP_080004674.1|982433_983414_+|zinc-metalloprotease-HtpX
MRARCSKKSSMRKEKIMTNFEKIIAQNRLKTNAVLATYCVIFAFIGLLVDVIRINANDLGIALFKLMTFQIFPAITLIMFLVAFVVIVVCIQNFSSIMLSGDEYKLIDTSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWNESNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLLLQIVLPFLTLLLQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYANNDYKGIDQNSTRSAAYLFNAEMFSTHPSVKNRIQSLRRRVI
>NC_017376.1|WP_000426949.1|983414_983957_+|GTP-cyclohydrolase-I-FolE
MENFFNQFFENIGEDKNREGLKETPKRVQELWKFLYKGYKEDPKVALKSAYFQGVCDEMIVAQNIEFYSTCEHHLLPFLGNISLGYIPKEKIVGISAIAKLIEIYSKRLQIQERLTTQIAETFDEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDPKTRAEFMQLLKS
>NC_017376.1|WP_000070347.1|983972_984884_+|polyprenyl-synthetase-family-protein
MSNPNLSFYYNECERFESFLNHHHLHLESFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCSLVGQKDYSNQQTEYFKIALSIECLHTYSLIHDDLPCMDNASLRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNALLESHIIVELVKILSANGGIKGMILGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLMMGLVASGIKDEELFKWLQAFGLKTGLCFQVLDDIIDVTQDEKESGKTTHLDGAKNSFVNLLGLKKASGYAQTLKTEVLNDLNLLKPAYPLLQENLNALLNTLFKGKT
>NC_017376.1|WP_000722448.1|984880_985684_+|5'/3'-nucleotidase-SurE
MKKILLTNDDGYHAKGIKALEQALEEMAEIYVVAPKHEKSACSQCITITAPLRAEKIKGKEGRHYRIDDGTPSDCVYLAINELFKHVCFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTKGYPLKGRKLLNVNVPNCSLQEYKGERITPKGYRLYKKEVHKRTDPKNESYFWLGLHPLEWQKRENEDRLSDFDAIASNHASITPLNLDLTSYDDLKSLESWHEGMLK
>NC_017376.1|WP_000041788.1|985680_986340_+|hypothetical-protein
MSKNHRLAFLGLIVGVFFFFNACQHRLHMEYYSEVTGDYLFNYNSTIVVAYDRSDAMTSYYINVIVYELQKLGFYNVFTQAEFPLDKAKNVIYARIVRNISAVPFYQYNYQLIDQVNKPCYFLGGQFYCSQTPTDYYAINGFSEQILMSANSHFILDWYDVVLQKRVLYVDGSVSGRTCGYQMLYRDLIKSTIKRIDFNRPERYYYNLRLPLYQPCYRE
>NC_017376.1|WP_000236873.1|986341_986944_+|6-pyruvoyl-tetrahydropterin-synthase-family-protein
MVIRRLYQFCASHVVRNCSSIKCAQNIHGHNYEVEVFIETNRLDRANMALDFGLMQQEMQTFIDSFDHAHHFWDKESVEFQRFIENHCVRYVKCSFNLSAESYALMFLYYLTRILQKSVFSNNEGELKVSSVRVHETKNGYAESFLKDLENPHFKSLVHPNCVSFSQGIQNLWHDKDFFNKIVSDEKQCFFHAKPLHQIP

Crispr_ID: NC_017376_3

• CRISPR_ID: NC_017376_3
• CRISPR_location: 1539420-1539528
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NC_017376_3

Consensus_repeat	Method
TTTTGTTGTAAAACTTATTTTTTTAA	CRISPRCasFinder

spacers of NC_017376_3

>3.1|1539446|57|NC_017376|CRISPRCasFinder
CAAGCTCTTTTATTGTTTGAATGTAAAAAATGCTAAAAAGCATTTTTTAGGTTTCAT

CRISPR arrays and Neighbor proteins around NC_017376_3

CRISPR arrays

The CRISPR arrays of NC_017376_3

>merge|NC_017376|3|1539420-1539528|CRISPRCasFinder
TTTTGTTGTAAAACTTATTTTTTTAACAAGCTCTTTTATTGTTTGAATGTAAAAAATGCTAAAAAGCATTTTTTAGGTTTCATTTTTGTTGTAAAACTTATTTTTTTAA

>NC_017376|3|3|1539420-1539528|CRISPRCasFinder
TTTTGTTGTAAAACTTATTTTTTTAA	CAAGCTCTTTTATTGTTTGAATGTAAAAAATGCTAAAAAGCATTTTTTAGGTTTCAT
TTTTGTTGTAAAACTTATTTTTTTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017376.1|WP_000152053.1|1545851_1546994_+|alanine-dehydrogenase	unknown	unknown	gnl|CDD|223758
NC_017376.1|WP_000751642.1|1532626_1534069_-|hypothetical-protein	unknown	unknown	unknown
NC_017376.1|WP_014536827.1|1554333_1555197_-|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|236281
NC_017376.1|WP_000461837.1|1536394_1536634_+|DUF2443-domain-containing-protein	unknown	unknown	gnl|CDD|371028
NC_017376.1|WP_014536824.1|1549757_1550612_+|NAD(+)/NADH-kinase	unknown	unknown	gnl|CDD|223139
NC_017376.1|WP_000713200.1|1548844_1549573_-|outer-membrane-protein	unknown	unknown	gnl|CDD|280099
NC_017376.1|WP_000380564.1|1534297_1535665_-|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl|CDD|273037
NC_017376.1|WP_154079247.1|1541376_1541712_+|DUF45-domain-containing-protein	unknown	unknown	gnl|CDD|307807
NC_017376.1|WP_000604377.1|1544679_1545648_-|arginase	unknown	unknown	gnl|CDD|162262
NC_017376.1|WP_001204418.1|1550626_1552201_+|DNA-repair-protein-RecN	unknown	unknown	gnl|CDD|223571
NC_017376.1|WP_000539080.1|1553522_1553819_+|hypothetical-protein	unknown	unknown	unknown
NC_017376.1|WP_000837037.1|1530711_1531059_+|hypothetical-protein	unknown	unknown	unknown
NC_017376.1|WP_000549196.1|1541800_1544326_-|TonB-dependent-receptor-family-protein	unknown	unknown	gnl|CDD|227113
NC_017376.1|WP_000451926.1|1538451_1539078_+|FAD-dependent-thymidylate-synthase	unknown	unknown	gnl|CDD|224270
NC_017376.1|WP_000922956.1|1535816_1536359_+|hypothetical-protein	unknown	unknown	gnl|CDD|223846
NC_017376.1|WP_001158362.1|1528758_1530630_-|ATP-dependent-DNA-helicase-RecG	unknown	unknown	gnl|CDD|273192
NC_017376.1|WP_000668024.1|1531062_1531698_+|outer-membrane-protein	unknown	unknown	gnl|CDD|280099
NC_017376.1|WP_000334426.1|1536634_1538428_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|273462
NC_017376.1|WP_000667782.1|1552197_1553505_+|fibronectin-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224212
NC_017376.1|WP_000780318.1|1531694_1532447_-|exodeoxyribonuclease-III	unknown	unknown	gnl|CDD|139971

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017376.1|WP_014536827.1|1554333_1555197_-|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	6.5e-37	121.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017376.1|WP_000152053.1|1545851_1546994_+|alanine-dehydrogenase	gnl|CDD|223758	COG0686, Ald, Alanine dehydrogenase [Amino acid transport and metabolism].	7.65407e-176
NC_017376.1|WP_014536827.1|1554333_1555197_-|3'-5'-exonuclease	gnl|CDD|236281	PRK08517, PRK08517, 3'-5' exonuclease.	2.99573e-137
NC_017376.1|WP_000461837.1|1536394_1536634_+|DUF2443-domain-containing-protein	gnl|CDD|371028	pfam10398, DUF2443, Protein of unknown function (DUF2443). This is a small family of highly conserved proteins from bacteria, in particular Helicobacter species, The structure is a bundle of alpha helices. The function is not known.	1.96254e-34
NC_017376.1|WP_000713200.1|1548844_1549573_-|outer-membrane-protein	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	2.31776e-46
NC_017376.1|WP_000380564.1|1534297_1535665_-|chromosomal-replication-initiator-protein-DnaA	gnl|CDD|273037	TIGR00362, DnaA, chromosomal replication initiator protein DnaA. DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair].	7.74525e-161
NC_017376.1|WP_154079247.1|1541376_1541712_+|DUF45-domain-containing-protein	gnl|CDD|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	2.15313e-33
NC_017376.1|WP_014536824.1|1549757_1550612_+|NAD(+)/NADH-kinase	gnl|CDD|223139	COG0061, nadF, NAD kinase [Coenzyme metabolism].	4.0069e-79
NC_017376.1|WP_001204418.1|1550626_1552201_+|DNA-repair-protein-RecN	gnl|CDD|223571	COG0497, RecN, ATPase involved in DNA repair [DNA replication, recombination, and repair].	1.89664e-128
NC_017376.1|WP_001158362.1|1528758_1530630_-|ATP-dependent-DNA-helicase-RecG	gnl|CDD|273192	TIGR00643, ATP-dependent_DNA_helicase_RecG, ATP-dependent DNA helicase RecG. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_017376.1|WP_000549196.1|1541800_1544326_-|TonB-dependent-receptor-family-protein	gnl|CDD|227113	COG4772, FecA, Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism].	0
NC_017376.1|WP_000451926.1|1538451_1539078_+|FAD-dependent-thymidylate-synthase	gnl|CDD|224270	COG1351, THY1, Predicted alternative thymidylate synthase [Nucleotide transport and metabolism].	5.63382e-72
NC_017376.1|WP_000922956.1|1535816_1536359_+|hypothetical-protein	gnl|CDD|223846	COG0775, Pfs, Nucleoside phosphorylase [Nucleotide transport and metabolism].	3.36495e-06
NC_017376.1|WP_000604377.1|1544679_1545648_-|arginase	gnl|CDD|162262	TIGR01229, rocF_arginase, arginase. This model helps resolve arginases from known and putative agmatinases, formiminoglutamases, and other related proteins of unknown specifity. The pathway from arginine to the polyamine putrescine may procede by hydrolysis to remove urea (arginase) followed by decarboxylation (ornithine decarboxylase), or by decarboxylation first (arginine decarboxylase) followed by removal of urea (agmatinase).	1.78936e-136
NC_017376.1|WP_000668024.1|1531062_1531698_+|outer-membrane-protein	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	1.66995e-34
NC_017376.1|WP_000334426.1|1536634_1538428_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|273462	TIGR01135, glmS, glucosamine--fructose-6-phosphate aminotransferase (isomerizing). The member from Methanococcus jannaschii contains an intein. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Central intermediary metabolism, Amino sugars].	0
NC_017376.1|WP_000667782.1|1552197_1553505_+|fibronectin-binding-domain-containing-protein	gnl|CDD|224212	COG1293, COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription].	1.64778e-45
NC_017376.1|WP_000780318.1|1531694_1532447_-|exodeoxyribonuclease-III	gnl|CDD|139971	PRK13911, PRK13911, exodeoxyribonuclease III; Provisional.	0

Protein sequences

>NC_017376.1|WP_000451926.1|1538451_1539078_+|FAD-dependent-thymidylate-synthase
MEVICKHYTPLDIASQAIRTCWQSFEYSDDGGCKDKELIHRVGNIFRHSSTLEHLYYNFEIKGLSRGALQELSRHRIASLSVKSSRYTLRELKEVESFLPLNETNLERAREFLVFVDNEKVNAMSVLALENLRVLLSEHNIKNDLAKYAMPESYKTHLAYSINARSLQNLLTLRSSNKALKEMQDLAKALFDALPCEHQYLFEDCLKH
>NC_017376.1|WP_000334426.1|1536634_1538428_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGDSEKKSVLLEGLKELEYRGYDSAGLAVLSGDCLEVFKTQGKLENLKSELKNKEFLDFGVSVAHTRWATHGKPSSANAHPHFTENLALVHNGIIENYASLKKELENKGHAFLSQTDTEVIAHLLEETLKSESDLLKAFEKSISLLKGSYAILMLHKRAKESLFYAKSSSPLVVGKGKDGVFFASSLSVLAPKVDQFVILEENSVGRISLENFKDLKNIENMKDYAFENKDYSKGDFRNYLEKEIYEQHSSLLECLEGRLEALNVYCEIDPKFLENVSEITLCSCGSSYHASLASVYLFERLAKIRARAILASEYRYAHFKSNPNELFIAISQSGETADTLEALKLAKAQGLKTISLCNAPFSMMSRISDHTLLIRAGVERSVASTKAFSSQVMLLWLLSVYIGKQLGTISKEEEKIQAKNMLNSVNAMKVEPRLHEKIKRLSKRYLHGHGFFYIGRDVFYPLALEGALKLKEISYLHAEGYASAEMKHGPIALVDSNLFTIALLSKHLLFDKTKSNIEELSARDSTICVLSSEILEIADDFIQLEESESYMEEFFRMNLAVQLLALEIAMRLNHDVDHPRNLAKSVTVE
>NC_017376.1|WP_000461837.1|1536394_1536634_+|DUF2443-domain-containing-protein
MFEKIRKILADIEDSQNEIEMLLKLANLSLGDFIEIKRGSMDMPKGVNEAFFTQLSEEVERLKELINALNKIKKGLLVF
>NC_017376.1|WP_000922956.1|1535816_1536359_+|hypothetical-protein
MLLCAGRNETLKGATPIGVGLIESAIHLTRMCLKNPHAESLIFIGSAGSYSPEIELLSVFESVCGYQIEESFSHLNSYTPLDNFIQIETKEEALFERVCVNSSNYIHTNEMFAKKMAQKGVLLENMEFFSVLSVAKIFSLKAKGIFCVSNYIGLNVHKEFKENHAKVKQILENVIDSLRL
>NC_017376.1|WP_000380564.1|1534297_1535665_-|chromosomal-replication-initiator-protein-DnaA
MDTNNNIEKEILALIKQEVSLIEYENCLSQLKYNPNASKSDIAFFYAPNMLLCNWITAKHGALLKKILSQNKVGMHLAHSVDVRIEVAPKIQISAQTNINYKAIKTSVKDSYTFENFVVGSCNNTVYEIAKKVAQSDTPPYNPVLFYGGTGLGKTHILNAIGNHALEKRKKVVLVTSEDFLTDFLKHLDNKAMDSFKKKYRHCDFFLLDDAQFLQGKPKLEEEFFHTFNDLHANSKQIVLISDRSPKNIAGLEDRLKSRFEWGITAKVMPPDLETKLSIVKQKCQLNKITLPEEVMEYIAQHISDNIRQMEGAIIKISVNANLMNATIDLNLAKTVLEDLQKDHAEGSSLENILLAVAQSLNLKSSEIKVSSRQKNVALARKLVVYFARLYTPNPTLSLAQFLDLKDHSSISKMYSNVKKILEEEKSPFILSLREEIKNRLTELNDKKTAFNSSE
>NC_017376.1|WP_000751642.1|1532626_1534069_-|hypothetical-protein
MKKTLCLSFFLTFSNPLQALVIELLEEIKTSPHKGTFKAKVLDSKEPKQVLGVYNISPHKKLTLTITHISTAIVYQPLDEKLSLETTLNPNRPTIPRNTQIVFSSKELKESHPHQMPSLNAPMQKPQNKPHSSQQPPQNFSYPEPKLGSKNSKNSLLQPLITPSKTSPTNEVKTPTNDTKPPLKHSSEDQENNLFIAPPTEKTLPNNTPNTDISENNESHENNRDNVEKQAIRDPNIKEFACGKWVYDDENLQAYRPSILKRVDEDKQTATDITPCDYSHAENKSGKITTPYTKISVHKTEPLEEPQTFEAKNNFTILQARSSTEKCKRARARKDGTIRQCYLIEEPLKQAWESEYQITTQLVKAVYERPKQDDQVEPTFYETSELAYSSTRKSEVTRNELNLNEKFMEFVEVYEGHYLNDIVKESSEYKEWVKNHVRFKEGVCMVLEIEEQPRAKSTPLSIENSRVVCVKKGNYLFNEV
>NC_017376.1|WP_000780318.1|1531694_1532447_-|exodeoxyribonuclease-III
MKLVSWNVNGLRACMTKGFMDFFNSVDADVFCIQESKMQQEQNTFEFKGYFDFWNCALKKGYSGVVTFSKKEPLSVSYGINIEEHDKEGRVVTCEFESFYLVNVYTPNSQQALSRLSYRMSWEVEFKKFLKALELKKPVIVCGDLNVAHNEIDLENPKTNRKNAGFSDEERGKFNELLNAGFIDTFRYFYPNKEKAYTWWSYMQQARDKDIGWRIDYFLCSNPLKTRLKDALIYKDILGSDHCPVGLELV
>NC_017376.1|WP_000668024.1|1531062_1531698_+|outer-membrane-protein
MKFFSKDLFKKVIPLFLSVYFLNPTITQAKSRFYVASQYQVGKMIMKKYNDLKRTIEGASFSLGWEINPTNYWFYSRYYFFMDYGNVILNKRTGAQANMFTYGFGGDLIVEYNKNPLYVLSLFYGMQVAENTWTISKHSANFIIDDWRSIQGFSLKTSNFRMLGLVGFKFQTVLFHHDASIEVGVKWPFAFEYNSPFVRLFSVFISHTFYL
>NC_017376.1|WP_000837037.1|1530711_1531059_+|hypothetical-protein
MKSKITHFIAISFVLSLFSACKDEPKKSSQSHQNNTKTTQNNPINQANKDIKKIEHEEEDEKATKEVNDLINNENKIDEINNEENADPSQKRTNNVLQRATNHQDNLSSPLNRKY
>NC_017376.1|WP_001158362.1|1528758_1530630_-|ATP-dependent-DNA-helicase-RecG
MQETDNLLKTLNVKSLLEALLVYTPKGYKDLNLLEHFETGLSGVLEVDILDKRNYAKVLKIFAYSKRFYKNLELVFFNYSAFHHSQFKTGESLFIYGKLEQSSFNQAYIINTPKILTEFGKISLIFKKVKNHKKIQENLQKLISLENLKKEGIKENIARLLLEIFFPTPHFVKDFETNKNFPSQHLNALKYIEMLFYMKNLERKKLQFNAKIACPNNSERLKAFIASLPFKLTNDQQNAIKEIQSDLTSSIACKRLIVGDVGCGKTMVILASMVLAYPNKTLLMAPTSILAKQLYNEALKFLPHYFEVELLLGGSRKKRSNHLFETITHVVIGTQALLFDKRDLDEFALVITDEQHRFGTKQRYQLEKMASSKGNKPHSLQFSATPIPRTLALAKSAFVKTTMIREIPYPKEIETLVLHKRDFKIVMEKISEEIAKNHQVIVVYPLVNESEKIPYLSLSEGASFWQKRFKNVYTTSGQDKNKEEVIEEFREFGSILLATTLIEVGISLPRLSVMVILAPERLGLATLHQLRGRVSRNGLKGYCFLCTIQEENERLEKFAEELDGFKIAELDLEYRKSGDLLQGGEQSGNSFEYIDLAKDENIIAEVKQDFLKAASVLRGTFEN
>NC_017376.1|WP_154079247.1|1541376_1541712_+|DUF45-domain-containing-protein
MLENYYRQVLREKIQTYINQYEKILNESIQSFKIQKMKRIWGSCNATKRTLLFNLELIKAPSEGIEYVVVHELLHLKTRHHNEYFRDLLSLYLPNWQRAKTSLKETYLERS
>NC_017376.1|WP_000549196.1|1541800_1544326_-|TonB-dependent-receptor-family-protein
MHKKVLLVLTASLICQESLFAKEKDYTLGKVSTAGKKDKSDYSGQVNLGYSGITAPKSWQDEEVKKYTGSRTVISNKALTQQANQSIEEALQNVPGLQIRNATGVGAMPTIQIRGFGAGGSGHSDATLMLVNGIPVYMAPYAHIELDIFPVTFQAIDRIDVIKGGGSVQYGPNTYGGIVNIITKPIPNQWENQAAERITYWAKARNAGFAAPPDKTGDPSFIKSLGNNLLYNTYVRSGGMINKHVGIQAQANWVRGQGFRDNSPSSISNYWLDGVYDINENNGIKAYYQYYDFAIAQPGSLSEQDYKINRFANLRPLNQKGGRSQRFGAVYENRFGDLDRVGGTFSFTYYGQLMTRDFQVSSSYNSANMVTCFSEAACRAAGLPAGYNLAVPYYATNYNGWAEVENPVRSINNAFEPKVNLIVNTGKVKQTFIMGLRFMTTTFLQRQYLNTNECATKTSGEGAGFLCEGANVMSGWQPHIKHGVYRNWNNWRNNYTAVYLSDRIEAWDGRFFIVPGLRYAFVQYNNENAANWVQIPEKDLRKIKHMNNWMPSTNIGFIPVQGDHNVLTYFNYQRSFVPPQLDVLSYGGAEYFTQHFDTVEAGARYSYKDKFSFNADYFRIWARDFATGQYSVYTSGPMKGNVRPINGYSQGVELELYYRPIRGLQFHAAFNYIDTRVTSHGPLTDLNGDVLKGTSYNKHFPFVSPFQFIFDARYNWRKTTIGISSYFYSRAYSGISNSAAGGYYGMQYYSGGNNYESVLNSGYQCEAWCMTQHEGLLPWYWVWNIQVSQIFWENGRHRVTGSLQINNIFNMKYYFTGIGSSPAGLQPAPGRSVTAYLNYTF
>NC_017376.1|WP_000604377.1|1544679_1545648_-|arginase
MILVGLEAELGASKRGTDKGVRLLREALSTTHGDVIKGMQTITQERCVLYKEFRYAKNFEDYYLFCKENLIPCMREVFEKKEFPLILSSEHANMFGIFQAFRSVHKDKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMSESEEKAWQKLCSLGLEKGGLEIDPKCLVYFGVRSTEKSERDVIKELQIPLFSVDAIRENMQEVVQKTKESLKAVDIIYLSLDLDIMDGKLFTSTGVRENNGLSFDELKQLLGLLLESFKDRLKAVEVTEYNPTVSAKHTNEEEKQVLEILDLIINSCKIKDKKHSFARSY
>NC_017376.1|WP_000152053.1|1545851_1546994_+|alanine-dehydrogenase
MTIGLVKESMDLESRVALVPDDVALIIQKGVEVLVQNSAGANSGYSNEAYESVGAKIVDSKTAWRQDLVVKCKEPLEHEYPLLKEKATLFSYLDLAYQKSLCEMFIDKKITSICTETIAGPKNDYPILAPMSVVAGRLAAHLVQHYLLALEHVKGFMGKGVMLGGLSGAQRAKIVVVGGGVVGMESAKVLSQMGAKVTILELDYAKLQNHPYYHLYGLEVLSVNEANIIQALNGAVGLVGAVLVTASQTPKVILRRHLKRMQKQGVVIDVACDLGGCIETIHQTSHSNPVYVEEDLLHYGVPNMPGIAAKTSSVAYSHASAPYLLYYLEHGLKGFLTANTKIVANTLGGLSAYNGYITQEGIAKAFNLAFKSPLEVLKEL
>NC_017376.1|WP_000713200.1|1548844_1549573_-|outer-membrane-protein
MKKFFSQSLLALIVSVNALLAMDGNGVFLGAGYLQGQAQMHADINSQKQATNATIKGFDALLGYQFFFGKYFGLRAYGFFDYAHANSIRLKNPNYNSEAAQVAGQILGKQEINRLTSIADPKTFEPNMLTYGGAVDVMVNVINNGIMSLGAFGGVQLAGNSWLMATPSFEGLLVEQALVSKKATSFQFLFNVGARLRILKHSSIEAGVKFPMLKKNPYITAKNLDIGFRRVYSWYVNYVFTF
>NC_017376.1|WP_014536824.1|1549757_1550612_+|NAD(+)/NADH-kinase
MKDSPQTIGVFVRPTHYQNPLFEKLERAKEWVLKLLEDEGFESFMIDSLDGAKDERLVEKAYAFLCLGGDGTILGALRMTHSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDLKQGAIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYAGHTPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRSLVLGAEFCLNFCAHEDALVVIDGQATYDLKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPNKKR
>NC_017376.1|WP_001204418.1|1550626_1552201_+|DNA-repair-protein-RecN
MRDFNNAQITRLKVRQNAVFEKLDLEFKDGLSAISGASGVGKSVLIASLLGAFGLKESNASNIEVELIAPFLDTEEYGIFREDEHEPLVISVIKKEKTRYFLNQTSLSKNALKALLKGLIKRLSNDRFSQNELNDTLMLSLLDGYIHNENKAFSPLLGALEKKFTRLEKLEKERRLLENKKRFQKDLEERLNFEKMKLERLDLKEDEYERLLEQKKLLSSKEKLNDKIALALEVLENTHKITHALESVGHSAEFLKSALLEASALLEKEQAKLEECERLDIEKVLERLGMLSGIIKDYGSIMHAKERLGHVKNELHNLKEIDHHCETYHKETEQLKTECLKLCEEISGFRKEYLAGFNALLSAKAKDLLLKSPSLVLEEAPMSEKGAQKLVLNLQNSQLETLSSGEYSRLRLAFMLLEMEFLKDFKGVLVLDEMDSNLSGEESLAVSKALETLSSHSQIFAISHQVHIPALAKNHILVFKENHKSLAKTLNNEERVLEIARMIGGSENIESAISFAKEKLKAQE
>NC_017376.1|WP_000667782.1|1552197_1553505_+|fibronectin-binding-domain-containing-protein
MKFFLLKKFSEFLNAQTHFNLKRLNASGFLLETFSKEKHAFILDLNVPYIGLSKKPPESVLKNTLALDFCLNKFTKNAKILQANIVDNDRILEITGAKDLAYKSENFILRLEMIPKKTNLMILDKEKCVIEAFRFNDRVAKNDILGALPFNAYEHQEEDLDFKGLLDILEKDFLSYQHKELEHKKNQIIKRLNIQKERLKEKLEKLEDPKNLQLEAKELQTQASLLLTYQHLINRHESRVVLKDFEDKECAIEIDKSMPLNAFINKKFTLSKKKKQKSQFLYLEEENLKEKIAFKENQINYVKGAQEESVLEMFMPFKNSKIKRPMSGYEVLYYKDFKIGLGKNQKENIKLLQDARANDLWMHVRDIPGSHLIVFCQKNTPKDEVIMELAKMLVKMQKDAFNSYEIDYTQRKFVKIIKGANVIYSKYRTINLKDT
>NC_017376.1|WP_000539080.1|1553522_1553819_+|hypothetical-protein
MGVSALGNVTYINQNAPLNSAIQQGARSDMLDLAQSFQNKLELAQETRALENMQAISDKDPKEGSKNRYQNSQRAKAFGLEEEEIELWHEEHLLDIVG
>NC_017376.1|WP_014536827.1|1554333_1555197_-|3'-5'-exonuclease
MSDSLLHKDIQALIARLKHQDLSLGMLEKSLSRLIYDEVNLEYLKACGLNFVETSENLITLKNLKTPFKDEVFSFIDLETTGSCPLKHEILEIGAVQVKGGEIINRFETLVKVKSVPDYIAELTGIAYEDTLNAPSAHEALQELRLFLGNSVFVAHNANFDYNFLGRYFVEKLHCPLLNLKLCTLDLSKRAILSMRYSLSFLKELLGFGIEVSHRAYADALASYKLFEICLLNLPSYIKTTMDLIDFSQCANTLIKRPPRARHQETPPPFSLFERTKGLLNIIKATS

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017376_2	2.3|972941|25|NC_017376|CRT	972941-972965	25	HQ331142	Salmonella phage S16, complete genome	134114-134138	3	0.88
NC_017376_2	2.3|972941|25|NC_017376|CRT	972941-972965	25	JX181825	Salmonella phage STML-198, complete genome	15165-15189	3	0.88
NC_017376_2	2.3|972941|25|NC_017376|CRT	972941-972965	25	KJ000058	Salmonella phage STP4-a, complete genome	133583-133607	3	0.88
NC_017376_2	2.3|972941|25|NC_017376|CRT	972941-972965	25	NC_042044	Salmonella phage Melville, complete genome	132847-132871	3	0.88
NC_017376_2	2.2|972884|28|NC_017376|CRT	972884-972911	28	NZ_CP016620	Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence	209095-209122	5	0.821
NC_017376_2	2.6|972940|27|NC_017376|CRISPRCasFinder	972940-972966	27	HQ331142	Salmonella phage S16, complete genome	134113-134139	5	0.815
NC_017376_2	2.6|972940|27|NC_017376|CRISPRCasFinder	972940-972966	27	JX181825	Salmonella phage STML-198, complete genome	15164-15190	5	0.815
NC_017376_2	2.6|972940|27|NC_017376|CRISPRCasFinder	972940-972966	27	KJ000058	Salmonella phage STP4-a, complete genome	133582-133608	5	0.815
NC_017376_2	2.6|972940|27|NC_017376|CRISPRCasFinder	972940-972966	27	NC_042044	Salmonella phage Melville, complete genome	132846-132872	5	0.815
NC_017376_2	2.2|972884|28|NC_017376|CRT	972884-972911	28	NZ_LT960613	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence	63179-63206	6	0.786
NC_017376_2	2.5|972883|30|NC_017376|CRISPRCasFinder	972883-972912	30	NZ_LT960613	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence	63178-63207	6	0.8
NC_017376_2	2.2|972884|28|NC_017376|CRT	972884-972911	28	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	752262-752289	7	0.75
NC_017376_2	2.5|972883|30|NC_017376|CRISPRCasFinder	972883-972912	30	NZ_CP016620	Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence	209094-209123	7	0.767
NC_017376_2	2.5|972883|30|NC_017376|CRISPRCasFinder	972883-972912	30	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	752261-752290	8	0.733

1. spacer 2.3|972941|25|NC_017376|CRT matches to HQ331142 (Salmonella phage S16, complete genome) position: , mismatch: 3, identity: 0.88

gtaacgccagcttcaataacgacac	CRISPR spacer
gaatcgccagcttcaataactacac	Protospacer
* * **************** ****

2. spacer 2.3|972941|25|NC_017376|CRT matches to JX181825 (Salmonella phage STML-198, complete genome) position: , mismatch: 3, identity: 0.88

gtaacgccagcttcaataacgacac	CRISPR spacer
gaatcgccagcttcaataactacac	Protospacer
* * **************** ****

3. spacer 2.3|972941|25|NC_017376|CRT matches to KJ000058 (Salmonella phage STP4-a, complete genome) position: , mismatch: 3, identity: 0.88

gtaacgccagcttcaataacgacac	CRISPR spacer
gaatcgccagcttcaataactacac	Protospacer
* * **************** ****

4. spacer 2.3|972941|25|NC_017376|CRT matches to NC_042044 (Salmonella phage Melville, complete genome) position: , mismatch: 3, identity: 0.88

gtaacgccagcttcaataacgacac	CRISPR spacer
gaatcgccagcttcaataactacac	Protospacer
* * **************** ****

5. spacer 2.2|972884|28|NC_017376|CRT matches to NZ_CP016620 (Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.821

gtgctcaatctgcttttgaaaacagcag	CRISPR spacer
atgctcactctgcttctgaaaacatctg	Protospacer
.****** *******.******** * *

6. spacer 2.6|972940|27|NC_017376|CRISPRCasFinder matches to HQ331142 (Salmonella phage S16, complete genome) position: , mismatch: 5, identity: 0.815

ggtaacgccagcttcaataacgacacc	CRISPR spacer
tgaatcgccagcttcaataactacaca	Protospacer
 * * **************** **** 

7. spacer 2.6|972940|27|NC_017376|CRISPRCasFinder matches to JX181825 (Salmonella phage STML-198, complete genome) position: , mismatch: 5, identity: 0.815

ggtaacgccagcttcaataacgacacc	CRISPR spacer
tgaatcgccagcttcaataactacaca	Protospacer
 * * **************** **** 

8. spacer 2.6|972940|27|NC_017376|CRISPRCasFinder matches to KJ000058 (Salmonella phage STP4-a, complete genome) position: , mismatch: 5, identity: 0.815

ggtaacgccagcttcaataacgacacc	CRISPR spacer
tgaatcgccagcttcaataactacaca	Protospacer
 * * **************** **** 

9. spacer 2.6|972940|27|NC_017376|CRISPRCasFinder matches to NC_042044 (Salmonella phage Melville, complete genome) position: , mismatch: 5, identity: 0.815

ggtaacgccagcttcaataacgacacc	CRISPR spacer
tgaatcgccagcttcaataactacaca	Protospacer
 * * **************** **** 

10. spacer 2.2|972884|28|NC_017376|CRT matches to NZ_LT960613 (Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence) position: , mismatch: 6, identity: 0.786

gtgctcaatctgcttttgaaaacagcag	CRISPR spacer
gtgctcaccctgcttttgaaaacgcaaa	Protospacer
******* .**************.  *.

11. spacer 2.5|972883|30|NC_017376|CRISPRCasFinder matches to NZ_LT960613 (Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence) position: , mismatch: 6, identity: 0.8

agtgctcaatctgcttttgaaaacagcagc	CRISPR spacer
agtgctcaccctgcttttgaaaacgcaaac	Protospacer
******** .**************.  *.*

12. spacer 2.2|972884|28|NC_017376|CRT matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 7, identity: 0.75

gtgctcaatctgcttttgaaaacagcag	CRISPR spacer
caaggcaatctccttttgaaaacagcaa	Protospacer
  .  ****** ***************.

13. spacer 2.5|972883|30|NC_017376|CRISPRCasFinder matches to NZ_CP016620 (Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.767

agtgctcaatctgcttttgaaaacagcagc	CRISPR spacer
gatgctcactctgcttctgaaaacatctgg	Protospacer
..****** *******.******** * * 

14. spacer 2.5|972883|30|NC_017376|CRISPRCasFinder matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 8, identity: 0.733

agtgctcaatctgcttttgaaaacagcagc	CRISPR spacer
tcaaggcaatctccttttgaaaacagcaac	Protospacer
   .  ****** ***************.*