CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_015968	Enterobacter soli, complete sequence	1 crisprs	RT,cas3,DEDDh,csa3,WYL,DinG	1	0	5
NC_015969	Enterobacter soli plasmid pENTAS02, complete sequence	0 crisprs	NA	0	0	1
NC_015963	Enterobacter soli plasmid pENTAS01, complete sequence	1 crisprs	NA	0	1	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015968_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015968_1

540230-540376

Orphan

Consensus_repeat	Method
GTTTTCTCCCTCTCCCTGTGGGAGAGGGTTGGGGTGAGGGCATCAGGCCGCAC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_015968_1

>merge|NC_015968|1|540230-540376|CRISPRCasFinder
GTTTTCTCCCTCTCCCTGTGGGAGAGGGTTGGGGTGAGGGCATCAGGCCGCACAAGGTAAAAGCAAAACGGCAACCTCGGTTGCCGTTTTTAGTGTTTTCTCCCTCTCCCTGTGGGAGAGGGTTGGGGTGAGGGCATCAGGCCGCAC

>NC_015968|1|1|540230-540376|CRISPRCasFinder
GTTTTCTCCCTCTCCCTGTGGGAGAGGGTTGGGGTGAGGGCATCAGGCCGCAC	AAGGTAAAAGCAAAACGGCAACCTCGGTTGCCGTTTTTAGT
GTTTTCTCCCTCTCCCTGTGGGAGAGGGTTGGGGTGAGGGCATCAGGCCGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015968.1\|WP_014068718.1\|536932_537733_-\|hypothetical-protein	unknown	unknown	unknown
NC_015968.1\|WP_014068728.1\|546994_547393_+\|amino-acid-binding-protein	unknown	unknown	gnl\|CDD\|153180
NC_015968.1\|WP_014068720.1\|538603_538900_-\|SH3-domain-containing-protein	unknown	unknown	unknown
NC_015968.1\|WP_014068726.1\|545127_546543_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143456
NC_015968.1\|WP_014068716.1\|535106_535973_-\|hypothetical-protein	unknown	unknown	unknown
NC_015968.1\|WP_014068723.1\|542168_543557_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NC_015968.1\|WP_014068730.1\|548566_549034_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|179596
NC_015968.1\|WP_014068713.1\|532622_533621_-\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|183400
NC_015968.1\|WP_014068727.1\|546678_547002_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
NC_015968.1\|WP_014068719.1\|537970_538576_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|237133
NC_015968.1\|WP_014068721.1\|539103_540225_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|225406
NC_015968.1\|WP_014068724.1\|543659_544139_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NC_015968.1\|WP_167320598.1\|548206_548368_+\|hypothetical-protein	unknown	unknown	unknown
NC_015968.1\|WP_014068715.1\|534238_535048_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_015968.1\|WP_014068717.1\|536000_536909_-\|glycoside-hydrolase	unknown	unknown	gnl\|CDD\|119373
NC_015968.1\|WP_014068729.1\|547364_548060_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_015968.1\|WP_014068722.1\|541966_542128_+\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|227744
NC_015968.1\|WP_014068725.1\|544125_545028_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176163
NC_015968.1\|WP_014068714.1\|533819_534242_+\|FosA/FosA2-family-fosfomycin-resistance-glutathione-transferase	unknown	unknown	gnl\|CDD\|319908
NC_015968.1\|WP_014068712.1\|531888_532371_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015968.1\|WP_014068729.1\|547364_548060_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.98084e-13
NC_015968.1\|WP_014068728.1\|546994_547393_+\|amino-acid-binding-protein	gnl\|CDD\|153180	cd04908, ACT_Bt0572_1, N-terminal ACT domain of a novel protein composed almost entirely of two tandem ACT domains. Included in this CD is the N-terminal ACT domain of a novel protein composed almost entirely of two tandem ACT domains as seen in the uncharacterized structure (pdb 2F06) of the Bt0572 protein from Bacteroides thetaiotaomicron and related ACT domains. These tandem ACT domain proteins belong to the superfamily of ACT regulatory domains.	0.00195191
NC_015968.1\|WP_014068726.1\|545127_546543_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143456	cd07138, ALDH_CddD_SSP0762, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like. The 6-oxolauric acid dehydrogenase (CddD) from Rhodococcus ruber SC1 which converts 6-oxolauric acid to dodecanedioic acid, and the aldehyde dehydrogenase (locus SSP0762) from Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 and other similar sequences, are included in this CD.	0
NC_015968.1\|WP_014068721.1\|539103_540225_+\|cupin-domain-containing-protein	gnl\|CDD\|225406	COG2850, COG2850, Uncharacterized conserved protein [Function unknown].	4.18688e-155
NC_015968.1\|WP_014068714.1\|533819_534242_+\|FosA/FosA2-family-fosfomycin-resistance-glutathione-transferase	gnl\|CDD\|319908	cd07244, FosA, fosfomycin resistant protein subfamily FosA. This subfamily family contains FosA, a fosfomycin resistant protein. FosA is a Mn(II) and K(+)-dependent glutathione transferase. Fosfomycin inhibits the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase (MurA), which catalyzes the first committed step in bacterial cell wall biosynthesis. FosA, catalyzes the addition of glutathione to the antibiotic fosfomycin, (1R,2S)-epoxypropylphosphonic acid, making it inactive. FosA is a Mn(II) dependent enzyme. It is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.	3.16965e-72
NC_015968.1\|WP_014068730.1\|548566_549034_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|179596	PRK03573, PRK03573, transcriptional regulator SlyA; Provisional.	5.02187e-21
NC_015968.1\|WP_014068713.1\|532622_533621_-\|tryptophan--tRNA-ligase	gnl\|CDD\|183400	PRK12282, PRK12282, tryptophanyl-tRNA synthetase II; Reviewed.	0
NC_015968.1\|WP_014068722.1\|541966_542128_+\|DUF1127-domain-containing-protein	gnl\|CDD\|227744	COG5457, COG5457, Uncharacterized conserved small protein [Function unknown].	5.94931e-11
NC_015968.1\|WP_014068727.1\|546678_547002_+\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	2.87203e-17
NC_015968.1\|WP_014068719.1\|537970_538576_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|237133	PRK12553, PRK12553, ATP-dependent Clp protease proteolytic subunit; Reviewed.	1.38544e-103
NC_015968.1\|WP_014068715.1\|534238_535048_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.86865e-14
NC_015968.1\|WP_014068717.1\|536000_536909_-\|glycoside-hydrolase	gnl\|CDD\|119373	cd00599, GH25_muramidase, Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.	2.50294e-34
NC_015968.1\|WP_014068723.1\|542168_543557_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	4.07526e-120
NC_015968.1\|WP_014068725.1\|544125_545028_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176163	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 5. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.5276e-89
NC_015968.1\|WP_014068724.1\|543659_544139_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	3.94348e-26

>NC_015968.1|WP_014068721.1|539103_540225_+|cupin-domain-containing-protein
MAYQLNLNWPEFLEKYWQKQPVVLKNAFPNFVDPITPDELAGLAMEPEVDSRLVSHFNGKWQASNGPFEHFDDLGETGWSLLAQAVNHWHMPAAELVRPFRVLPDWRLDDLMISFSVPGGGVGPHIDQYDVFIIQGMGSRRWRVGDKLPMRQFCPHPALLHVDPFEPIIDEDLAPGDILYIPPGFPHDGFTHETALNYSVGFRGPNGRDLISSFADYALENDLGGEHYSDPDLTCREHPGRVEQYELDRIRQMMIDMISKPDDFTKWFGSFVSTPRHELDVAAAEPPYTPEEVLDALQGGETLTRLSGLRVLNIGGSFFINSEQLETVDANAADALCRFTSLGQAELGAALQNPAFVEELTDLINQGYWYFEE
>NC_015968.1|WP_014068720.1|538603_538900_-|SH3-domain-containing-protein
MSDFIEFPATGNVKTTTGVYTRRDNPSVFSPVACELPAGSRVTVLGAVVGDAVEGNAHWYRIDEDTFIWAGACTRLDPYPAFPENNRVNWMAVVFEVR
>NC_015968.1|WP_014068719.1|537970_538576_+|ATP-dependent-Clp-protease-proteolytic-subunit
MHYTMKESDNKDKAEGTHGAGALQQKLLDSRSIVISGEIDQALAEKVITQLILLQSISNDPIKLYINSQGGHVEAGDTIHDFIKFIRPEVHVIGTGWVASAGITIFLAAKKEHRYSLPNTRFMIHQPLGGVRGQATDIEIEAREIIRMLDRVNKLIADATGQPLEKVKKDTDRNFWMSPSEALDYGIVGKMITHYDDLKLD
>NC_015968.1|WP_014068718.1|536932_537733_-|hypothetical-protein
MPKASSGTLFWILGSLILFIAAPVIIENQQFAWLLTLVAMIIFCMGVGYAINGRLNGIFIDYRNRLSLSKLQALCWSMLILSAIYTAALLRIQKGILNPLEITLNEPLLAIMGISLTSLAAAPAILNAKADNNVTAQAAQQVSQALNKPVEDIIPAGKIFSFSSAELASWLDLFRGEENTNAGSADLGKIQQFVITFILLAIYGMSLWDFFSHPVAELNTFPDVSDHMSWLLGISHAGYLAYKAAPHGDASTPPPSTNNTTSSGAG
>NC_015968.1|WP_014068717.1|536000_536909_-|glycoside-hydrolase
MSNYPEIPLTGSVTTTVLVNVRQGAPSLQAPVVQKLAAGQTLAVLAAVIGDAFEGNAHWYRISISTFIWAGACTPASAHSITAPLQESSIDLSPVPLVVDLYHGDSVTSFQQAKNAGLAAVIHKATTGRKGRDDQYDNRRSDALAAGLLWGAYHWGTAANIAEQVDNFLTYANPDQNTLVALDFETTPGNQMTAQGVRDFSDAIFAKLNRRPVIYGSNLLREALGSTRDAFYHGHRLWLAQYGAHPTLPVHWDNYWLWQYTDGPTGPAGCRTVPGIPGNSRGHLDCNYFPGTLADLKSQWAS
>NC_015968.1|WP_014068716.1|535106_535973_-|hypothetical-protein
MVKHIGLVFVSGLLLAGCVQNNPLYKGFSSPEVDSTITTTSDTLMQILLNPPAVPEGTTKPVDVDHRDAIITKECANAGTAVDDEKGCQAQRNDAIYTLMTGSEQVCLAHRRSIYGNDAMFNISAGTLTSLFAGVATVVTPTVSKSIFSALAMFSNSERSLVNEVVYKQMIVTAVDTKIQQTRDTKAVAIVQHLKTDSMKDYPLSRALNDFMAYHNSCSFMEGLRLALANGTQNPTENKINTLNNRMLLNNAQMNIYCSGKKTDQAMCDSLVERNKAITDELKTLEVQ
>NC_015968.1|WP_014068715.1|534238_535048_-|GNAT-family-N-acetyltransferase
MELTAVSALHFSAAILTDILERCFQDYFVPFSLTPEAFALRFGSEGLSYEDSCVWLRGDEPVAIALIMRRAGAARLGAFAILPEYRGKGLARGMLTPLFTTLKAKGISPFYLEVIHENTAAIALYEALGFRISQGLWGFKGETTDVRMNGELREATLNDLLRAVWSAPGERMPWQLDPLSLHLMPCEIISDGAGAWAAFTTHNMKPLLRFLFVAPGSRGQGHARRMLQNLSALHPGICTPVAVPERFAPLFASAGYQPLAITQFEMTQG
>NC_015968.1|WP_014068714.1|533819_534242_+|FosA/FosA2-family-fosfomycin-resistance-glutathione-transferase
MLQSLNHLTLAVSNLQKSLAFWHDVLGLTLHARWDTGAYLTCGDLWLCLSYDETRRVVPPQDSDYTHYAFSVAEQDFEPFSHRLEQAGVTVWKQNKSEGASFYFLDPDGHKLELHVGNLAARLAACREKPYAGMTFYLQG
>NC_015968.1|WP_014068713.1|532622_533621_-|tryptophan--tRNA-ligase
MSTTILTGDRPTGPLHLGHYVGSLRQRVALQQTHNQFVLIADLQGLTDNGSNPQKIRDNIPEVLADYLAAGIDPNLTTICLQSALPALAELTMLYMNIVTVARVERNPTVKNEIAQKGFARSLPVGFMAYPISQAADITAFKAECVPVGDDQLPMIEQTNEIVHKMNSLLPAPVLRHCKAMLSDTSRLPGIDGSAKMSKSLGNTLHLSASEETIHRAVSAMYTDPNHLKVNDPGQIEGNVVFTYLDAFHPDKDKVAAMKAHYQTGGLGDRVCKNELEACLQELIAPMRERRAMYMRDRGELMAMLKRGTERAQGVTQATLREVKVGLGVPVF
>NC_015968.1|WP_014068712.1|531888_532371_-|hypothetical-protein
MQFYTNEFTAELKAEIDRSPFSDEELAAMPEDARAIIAEQEAFHRQHPVTAIWRIATAGSQTRLGGVVLPVAREATMLMDDGSYTSLIVKGDRVAYPDGTLATIMTSAGSAFSWKRQGVVLVGSLLDNDDEIISTPLGSTYLVTREGIPPYEDFLTWPGE
>NC_015968.1|WP_014068722.1|541966_542128_+|DUF1127-domain-containing-protein
MEFHENRSKRPFIAFVWMWKTVKNWYRINRTRRILSRMSDEQLKDVGLSRFDV
>NC_015968.1|WP_014068723.1|542168_543557_-|PLP-dependent-aminotransferase-family-protein
MKPGYHDIYTRYRDNITRGVLKPGDKVPAIRVLAEELKVARKTVETAYAILTGEGYLVSQGARGTRVNPDLLLPGHDAPAEQATGTLPESLISQRERSGFLRPGIPALDSFPYKKWLLLAGQATRSMRQEEMLNPPVLGWYPLRQAIARYLNISRGLSCTAEQVLITSGYSGSLRLILDTLASRSDKVVFEDPGYFMGQQLLKRIVPRLHTVPVDRSGMDTGYLLRHHHDARFAIVTPSHQSPLAVTLSLPRKQQLLDWASQNEAWIIEDDYDGEFHYTRKVLPSLKSLDQHDRVIFMGTFSKTIMPSLRMGYVVMPASTVAAFTDCADIVTSGQPVLTQKILTTFLNEGHFFRHLKKMRALYQIRRDWMIAALQEVYGDLFFTEQNDGGMHIVAFLSKGSGDREVARCWQQHQLQVNALSEWYRGSGKRYGLVMGYNNVRTYQEALNLLEGPKQQTLELLG
>NC_015968.1|WP_014068724.1|543659_544139_+|carboxymuconolactone-decarboxylase-family-protein
MSTRVNHHKATPALAKALSDLSMEVAKTSIDPALKHLIDIRVSQLNGCTFCLDMHSKEAKIAGERELRLYHLAAWRESPLFSAREKAALAFTEALTQIGVHGVSDALYRSVAEHFSDVEISELNFAIVAINAWNRLGITSRMEPGSLDVAYGLNKANLE
>NC_015968.1|WP_014068725.1|544125_545028_-|LysR-family-transcriptional-regulator
MHRSGLTELEVVLAVVRRGGFRAAAQELGMSATAVSNAVAGLESRLQTRLFNRTTRSVALTDAGQRFVARVGPALQEIRQASEEIHSDNDAPAGTLRLNVPNNIGPLFLDNLLIAYMQRYPKMRVETVSEARMIDIVAEGYDAGIRLAESVPQDMVAVALTPDIRQLIVATPDHFARYGIPQTPDDLLHHQGIGMRMSHGGLYRWELERRGEQYALAVPPRFATSDLFASIRAVKAGLGVGFLPELYIRQELESGELVSVLEDWTQPFAGLRLYYPGHRHVPPGLRALVALVREREITPD
>NC_015968.1|WP_014068726.1|545127_546543_+|aldehyde-dehydrogenase-family-protein
MHHIEQIFINGEFVTPHGTVRFDLYNPATAQVIGQVRLADEVDAERAIAAAKAAFPAWANTTRQERIAALKRMHAAVVARHDELLEAIIEEYGAPASRSAWMASYPADVIAQAIDALESFAFTTTAGAARVQMTPLGVAGLITPWNSDAGFICGKLATALAAGCTAVIKPSEMSALQTQIITEALRDAGLPPGVFNIVTGRGDTVGETISRHPDVAKISFTGSTHTGKAILRNAAESFKRVTLELGGKSPTIMLDDVDLAQAVPLVIQAGFMNSGQACVAGTRILVPQSRKAEMEHALAQAVAAVRSGDPRDSATEVGPMVSEKQWQRVQGYIRKGTEEGARLLAGGEGRPKGTQDGWFVRPTLFADVNNQMAIAREEIFGPVLCVIPYRDEEEAIAIANDTDYGLSALVLGSDAGRAQRVAEQIQSGRVLVNTLAHEPKAPFGGFKHSGVGREMGTWGISAFMEPKSILS
>NC_015968.1|WP_014068727.1|546678_547002_+|antibiotic-biosynthesis-monooxygenase
MIAVLFEAKAEPAHQARYLQLAAELKPLLADIDGFIDIERFQSLTTDGKILSLSWWRDEEAIRNWKHNVFHLAAQEEGRASIFAFYRIRVAQVIREYSSETGGHADV
>NC_015968.1|WP_014068728.1|546994_547393_+|amino-acid-binding-protein
MYDIHVIFENAPGELARFGQLLGRNGVGLEGGGVFGVDAHFLVEEGEKARRVLLAAGFRVQAVTKPLIRKLKQERPGELGEIACALAVQGVSILTQYSDHANHLILLTDNDKLAAEITEPWAAYVKDPITSR
>NC_015968.1|WP_014068729.1|547364_548060_+|winged-helix-turn-helix-transcriptional-regulator
MLKTQLPPDNSAALEQAIAAVAAAMADPSRVKMLCALMDGRAWTATELSTAADVAPSTASGHLARLVEGRLITCLSQGRHRYYHLAGHDVAALVEQMMGLSWSRITPPETTAPKGMREARTCYDHLAGTVAVQIYDFMQAEGWLEADGSALTLYGREQFLKLGILLSAHPRRKACCACLDWSERRFHLGGEAGAALLTHLENKGWIQRVAGYREVVVTASGRSAVRKYFSR
>NC_015968.1|WP_167320598.1|548206_548368_+|hypothetical-protein
MDAPRGRYLHGRFIAPDPKAERNKLRVSRSDDFLAGSPGRQGGGGEPPWHVHR
>NC_015968.1|WP_014068730.1|548566_549034_+|MarR-family-transcriptional-regulator
MSEDDLFSRRPMGMRMAMIVRQWRAVIDDAIVDTGLTQSSWTVMMQLQQLGDNVSVSELAEVQGIELPPLMRTLTQLEKQGYLLRTTSPYDKRIRLLALTPEGKAILNTLTQVIETFQARVSQNIAPEHIEIFSATLNQIACNLRTIREEDNKTE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_015968_1	1.1\|540283\|41\|NC_015968\|CRISPRCasFinder	540283-540323	41	NC_015968.1	452270-452310	0	1.0
NC_015968_1	1.1\|540283\|41\|NC_015968\|CRISPRCasFinder	540283-540323	41	NC_015968.1	3999547-3999587	1	0.976

1. spacer 1.1|540283|41|NC_015968|CRISPRCasFinder matches to position: 452270-452310, mismatch: 0, identity: 1.0

aaggtaaaagcaaaacggcaacctcggttgccgtttttagt	CRISPR spacer
aaggtaaaagcaaaacggcaacctcggttgccgtttttagt	Protospacer
*****************************************

2. spacer 1.1|540283|41|NC_015968|CRISPRCasFinder matches to position: 3999547-3999587, mismatch: 1, identity: 0.976

aaggtaaaagcaaaacggcaacctcggttgccgtttttagt	CRISPR spacer
aaggtaaatgcaaaacggcaacctcggttgccgtttttagt	Protospacer
******** ********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

2146908 : 2155490

Escherichia_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014070141.1\|2146908_2147523_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	6.2e-27	34.2
WP_014070142.1\|2147567_2148422_-	dimethyl sulfoxide reductase anchor subunit family protein	A0A077SK59	Escherichia_phage	1.2e-23	33.2
WP_014069571.1\|2148423_2149041_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	1.4e-74	59.1
WP_014070143.1\|2149051_2151490_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	1.4e-215	49.3
WP_014070144.1\|2151634_2151928_-	DUF1161 domain-containing protein	NA	NA	NA	NA
WP_080562856.1\|2152038_2152749_+	YnfC family lipoprotein	NA	NA	NA	NA
WP_014070146.1\|2152770_2153331_-	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_014070147.1\|2153346_2153685_-	DUF1283 family protein	NA	NA	NA	NA
WP_041162057.1\|2153837_2154164_+	YnfA family protein	A0A218MNG8	uncultured_virus	3.2e-22	54.5
WP_014070149.1\|2154275_2155490_+	starvation-sensing protein RspA	Q6A202	Oenococcus_phage	5.7e-48	30.0

DBSCAN-SWA_2

2863178 : 2911035

Cronobacter_phage(28.85%)

integrase,head,tail,holin,terminase

attL 2896643:2896658|attR 2916526:2916541

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014070777.1\|2863178_2863496_-	hypothetical protein	K7PGV5	Enterobacterial_phage	3.1e-38	75.2
WP_014070778.1\|2863495_2863735_-	hypothetical protein	K7P7N3	Enterobacteria_phage	2.6e-29	76.9
WP_014070779.1\|2863939_2865769_+	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	1.2e-65	30.3
WP_014070780.1\|2865803_2867966_-	hypothetical protein	F1C5A8	Cronobacter_phage	9.5e-38	59.1
WP_014070781.1\|2868024_2870502_-\|tail	phage tail protein	F1C5A7	Cronobacter_phage	0.0e+00	89.1
WP_014070782.1\|2870488_2870905_-	C40 family peptidase	F1C5F2	Cronobacter_phage	2.4e-67	85.3
WP_014070783.1\|2870867_2871338_-	hypothetical protein	F1C5F1	Cronobacter_phage	6.5e-77	90.4
WP_014070784.1\|2871337_2871835_-	hypothetical protein	F1C5F0	Cronobacter_phage	1.0e-88	90.9
WP_014070785.1\|2871834_2874168_-	tape measure protein	A0A1B1W284	Salmonella_phage	8.4e-149	49.2
WP_014070786.1\|2874225_2874600_-	hypothetical protein	A0A0M4QWT0	Salmonella_phage	7.9e-25	53.4
WP_014070787.1\|2874672_2875416_-	hypothetical protein	G0ZNE7	Cronobacter_phage	4.4e-59	50.4
WP_014070788.1\|2875466_2876222_-	Ig domain-containing protein	G0ZNE6	Cronobacter_phage	7.1e-57	51.8
WP_014070789.1\|2876281_2876665_-	hypothetical protein	F1C5E4	Cronobacter_phage	3.2e-37	55.9
WP_014070790.1\|2876661_2877030_-	hypothetical protein	F1C5E3	Cronobacter_phage	3.9e-45	74.6
WP_014070792.1\|2877427_2877775_-	hypothetical protein	G0ZNE2	Cronobacter_phage	1.6e-32	60.9
WP_014070793.1\|2877767_2878103_-	hypothetical protein	G8GWD9	Rhodobacter_phage	1.0e-31	66.3
WP_014070795.1\|2878266_2878545_-	hypothetical protein	NA	NA	NA	NA
WP_014070796.1\|2878544_2878925_-	hypothetical protein	F1C5E2	Cronobacter_phage	1.5e-31	56.9
WP_014070798.1\|2879337_2880393_-	DUF2184 domain-containing protein	R9TMI8	Aeromonas_phage	1.2e-102	52.9
WP_014070799.1\|2880389_2880851_-	hypothetical protein	B1GS72	Salmonella_phage	2.2e-29	50.3
WP_014070800.1\|2880850_2882221_-	hypothetical protein	F1C5D9	Cronobacter_phage	6.1e-123	52.1
WP_014070801.1\|2882244_2882589_+	hypothetical protein	NA	NA	NA	NA
WP_064555895.1\|2882589_2883597_-\|head	phage head morphogenesis protein	F1C5D8	Cronobacter_phage	3.8e-114	68.5
WP_014070803.1\|2883523_2884993_-	DUF1073 domain-containing protein	F1C5D7	Cronobacter_phage	9.0e-149	57.0
WP_014070804.1\|2885005_2886478_-\|terminase	terminase	A0A1W6JNY3	Morganella_phage	1.0e-248	82.5
WP_014070805.1\|2886477_2886993_-\|terminase	terminase small subunit	I6PDJ6	Cronobacter_phage	1.5e-66	75.3
WP_014070806.1\|2887022_2887229_+	hypothetical protein	NA	NA	NA	NA
WP_014070807.1\|2887386_2887605_-	hypothetical protein	NA	NA	NA	NA
WP_014070808.1\|2887734_2888184_-	hypothetical protein	NA	NA	NA	NA
WP_014070809.1\|2888649_2888874_-	hypothetical protein	A0A2H4J182	uncultured_Caudovirales_phage	2.3e-19	58.1
WP_041162086.1\|2889128_2889650_-	DUF2514 domain-containing protein	A0A291LBG9	Klebsiella_phage	1.3e-06	32.1
WP_088201865.1\|2889646_2890090_-	lysozyme	A0A0M4R365	Salmonella_phage	1.7e-47	66.4
WP_014070812.1\|2890073_2890415_-\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	6.3e-29	54.2
WP_014070813.1\|2891946_2892282_+	hypothetical protein	NA	NA	NA	NA
WP_014070814.1\|2892504_2893320_-	antitermination protein	K7P7B9	Enterobacteria_phage	2.3e-122	80.1
WP_014070816.1\|2893431_2894043_-	recombination protein NinG	A0A0M4RU10	Salmonella_phage	1.5e-60	71.4
WP_014070817.1\|2894035_2894206_-	NinE family protein	G8C7V4	Escherichia_phage	6.9e-21	87.3
WP_014070818.1\|2894198_2894654_-	recombination protein NinB	I6R9D0	Salmonella_phage	5.6e-33	47.2
WP_014070821.1\|2895435_2895777_-	hypothetical protein	NA	NA	NA	NA
WP_014070822.1\|2895779_2896091_-	hypothetical protein	NA	NA	NA	NA
WP_014070823.1\|2896087_2896384_-	DUF4406 domain-containing protein	A0A222YYT7	Escherichia_phage	1.3e-27	65.2
WP_014070824.1\|2896380_2896956_-	winged helix-turn-helix transcriptional regulator	G8C7U7	Escherichia_phage	6.9e-12	42.1
2896643:2896658	attL	NA	NA	NA	NA
WP_014070825.1\|2896957_2897647_-	replication P family protein	G8C7U6	Escherichia_phage	1.6e-127	96.9
WP_014070826.1\|2897643_2898579_-	replication protein	K7PGZ0	Enterobacteria_phage	1.4e-70	85.3
WP_014070827.1\|2898764_2899307_-	toxin YdaT domain-containing protein	M9NZI6	Enterobacteria_phage	3.1e-86	90.6
WP_000102594.1\|2899324_2899558_-	hypothetical protein	A0A0P0ZDD7	Stx2-converting_phage	2.6e-18	62.3
WP_014070828.1\|2899599_2900352_+	LexA family transcriptional regulator	A0A286S2B2	Klebsiella_phage	4.5e-72	63.5
WP_014070829.1\|2901421_2901610_+	hypothetical protein	NA	NA	NA	NA
WP_014070830.1\|2901620_2901779_+	hypothetical protein	G8C7T3	Escherichia_phage	4.6e-19	86.5
WP_000607101.1\|2901775_2901985_+	cell division protein FtsZ	M9NZE2	Enterobacteria_phage	3.9e-34	97.1
WP_014070831.1\|2902055_2902451_+	hypothetical protein	NA	NA	NA	NA
WP_014070832.1\|2902444_2902606_+	hypothetical protein	NA	NA	NA	NA
WP_014070833.1\|2902583_2903240_+	exodeoxyribonuclease X	A0A1W5PTR6	Pseudoalteromonas_phage	4.6e-20	33.3
WP_014070834.1\|2903243_2903909_+	hypothetical protein	A0A2D1GLT5	Escherichia_phage	4.9e-46	45.2
WP_014070835.1\|2903920_2904634_+	hypothetical protein	A0A2L1IV75	Escherichia_phage	1.6e-13	32.3
WP_014070836.1\|2904645_2904798_+	DUF1317 family protein	NA	NA	NA	NA
WP_014070837.1\|2904794_2906039_+	phosphoadenosine phosphosulfate reductase family protein	Q8W6P3	Burkholderia_virus	1.0e-44	34.0
WP_014070838.1\|2906050_2906653_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014070839.1\|2906649_2907231_-	hypothetical protein	NA	NA	NA	NA
WP_014070840.1\|2907475_2907706_+	hypothetical protein	S4TRP7	Salmonella_phage	8.5e-06	38.4
WP_014070841.1\|2907794_2907941_+	hypothetical protein	NA	NA	NA	NA
WP_041162087.1\|2907941_2908160_+	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	1.1e-18	66.2
WP_014070843.1\|2908159_2908672_+	class I SAM-dependent methyltransferase	H9C170	Pectobacterium_phage	1.6e-68	77.1
WP_014070844.1\|2908634_2908874_+	DUF4222 domain-containing protein	Q6H9Z8	Enterobacteria_phage	2.4e-11	47.4
WP_176408562.1\|2908883_2909051_+	stationary-phase-induced ribosome-associated protein	NA	NA	NA	NA
WP_014070845.1\|2909242_2909443_+	hypothetical protein	G8C7S1	Escherichia_phage	7.4e-22	72.7
WP_014070846.1\|2909451_2909697_+	excisionase family protein	Q8W657	Enterobacteria_phage	9.4e-27	67.9
WP_014070847.1\|2909742_2911035_+\|integrase	site-specific integrase	S4TSP2	Salmonella_phage	1.5e-176	66.2
2916526:2916541	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2973526 : 2981334

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014070907.1\|2973526_2974138_+	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	A0A2H4UVM0	Bodo_saltans_virus	1.6e-14	29.6
WP_014070908.1\|2974176_2975157_-	LPS O-antigen chain length determinant protein WzzB	NA	NA	NA	NA
WP_014070909.1\|2975350_2976355_+	NAD-dependent epimerase	A0A2K9KZK0	Tupanvirus	2.3e-18	24.5
WP_014070910.1\|2976411_2977578_-	UDP-glucose 6-dehydrogenase	A0A1J0FA55	Only_Syngen_Nebraska_virus	6.5e-110	52.7
WP_014070911.1\|2977829_2979236_-	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	1.5e-36	28.0
WP_014070912.1\|2979387_2980254_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	7.0e-109	65.6
WP_014070913.1\|2980269_2981334_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.0e-101	53.8

DBSCAN-SWA_4

3262336 : 3352527

Enterobacteria_phage(16.67%)

tRNA,integrase,head,tail,holin,portal,terminase,protease,capsid

attL 3307690:3307707|attR 3353246:3353263

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014071142.1\|3262336_3263149_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_014071143.1\|3263148_3264162_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_014071144.1\|3264229_3265366_-	4-phosphoerythronate dehydrogenase PdxB	A0A2R8FDS8	Brazilian_cedratvirus	3.6e-20	26.9
WP_014071145.1\|3265479_3266484_+	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_014071146.1\|3266552_3267731_-	MFS transporter	NA	NA	NA	NA
WP_014071147.1\|3267799_3269017_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_014071148.1\|3269175_3271176_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_014071149.1\|3271238_3271514_-	YfcL family protein	NA	NA	NA	NA
WP_014071150.1\|3271527_3272073_-	elongation factor P hydroxylase	NA	NA	NA	NA
WP_014071151.1\|3272072_3272882_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_014071152.1\|3272881_3273706_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_014071153.1\|3273708_3274794_-	chorismate synthase	A0A291AU41	Pandoravirus	8.5e-88	46.9
WP_041162095.1\|3274854_3275787_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_014071154.1\|3275932_3276484_+	endonuclease SmrB	NA	NA	NA	NA
WP_014071155.1\|3276521_3277007_-	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_014071156.1\|3277216_3279364_-	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_014071157.1\|3279363_3280674_-	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_014071158.1\|3280912_3281197_-	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_014071159.1\|3281568_3282915_+	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_014071160.1\|3282959_3283712_-	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_014071161.1\|3284026_3284956_+	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	3.1e-139	84.2
WP_014071162.1\|3285204_3285525_-	hypothetical protein	K7PGV5	Enterobacterial_phage	1.5e-40	77.4
WP_014071163.1\|3285524_3285764_-	hypothetical protein	K7P7E2	Enterobacteria_phage	9.8e-29	73.4
WP_128738905.1\|3285833_3286274_+	hypothetical protein	NA	NA	NA	NA
WP_014071165.1\|3286370_3288386_-	hypothetical protein	A0A291AXF7	Shigella_phage	7.7e-34	52.4
WP_014071166.1\|3288431_3291509_-	kinase	A0A286S259	Klebsiella_phage	8.7e-271	47.9
WP_014071167.1\|3291505_3291886_-	hypothetical protein	A0A286S2A6	Klebsiella_phage	2.5e-50	72.2
WP_014071168.1\|3291896_3292379_-	DUF1833 family protein	A0A286S2B1	Klebsiella_phage	2.6e-60	73.1
WP_014071169.1\|3292375_3292846_-	hypothetical protein	A0A286S298	Klebsiella_phage	1.5e-52	59.4
WP_014071170.1\|3292845_3295266_-\|tail	phage tail tape measure protein	A0A286S1S3	Klebsiella_phage	3.5e-142	43.0
WP_041162097.1\|3295269_3295524_-	hypothetical protein	A0A286S1P2	Klebsiella_phage	1.8e-25	65.1
WP_041162098.1\|3295535_3295916_-\|tail	phage tail assembly chaperone family protein, TAC	K7PJU9	Enterobacteria_phage	6.1e-41	70.2
WP_014071172.1\|3295966_3296449_-	hypothetical protein	Q9MCU9	Escherichia_phage	9.1e-50	57.7
WP_014071173.1\|3296502_3296871_-	hypothetical protein	K7PHI9	Enterobacteria_phage	3.7e-43	67.2
WP_041162260.1\|3296867_3297353_-	HK97 gp10 family phage protein	A0A0U3TGT7	Pseudomonas_phage	2.0e-44	56.9
WP_014071175.1\|3297345_3297681_-\|head	phage head closure protein	A0A286S2A2	Klebsiella_phage	5.9e-48	84.7
WP_014071176.1\|3297685_3297898_-	hypothetical protein	A0A286S2A5	Klebsiella_phage	4.8e-11	63.9
WP_014071177.1\|3297966_3298290_-\|head,tail	phage gp6-like head-tail connector protein	K7PKT4	Enterobacteria_phage	1.1e-19	45.5
WP_167320596.1\|3298333_3298525_+	hypothetical protein	NA	NA	NA	NA
WP_014071179.1\|3298671_3299880_-\|capsid	phage major capsid protein	U5P0G9	Shigella_phage	1.9e-189	83.4
WP_176408566.1\|3299894_3300545_-\|head,protease	HK97 family phage prohead protease	Q8W628	Enterobacteria_phage	1.9e-103	85.6
WP_014071181.1\|3300534_3301764_-\|portal	phage portal protein	Q8HAD4	Salmonella_phage	6.3e-204	82.9
WP_014071183.1\|3301957_3303691_-\|terminase	terminase large subunit	Q8HAD6	Salmonella_phage	0.0e+00	93.1
WP_014071184.1\|3303687_3304182_-\|terminase	phage terminase small subunit P27 family	Q8HAD7	Salmonella_phage	1.9e-82	91.5
WP_014071185.1\|3304313_3304664_-	HNH endonuclease	K7PHK9	Enterobacteria_phage	7.5e-54	79.3
WP_014071186.1\|3304772_3304961_-	hypothetical protein	A0A2I7RUD6	Vibrio_phage	8.5e-20	82.0
WP_014071188.1\|3305171_3305738_-	hypothetical protein	K7PHH7	Enterobacteria_phage	2.3e-60	77.3
WP_014071189.1\|3305734_3306175_-	lysozyme	A0A0M4R365	Salmonella_phage	3.3e-46	65.8
WP_014071190.1\|3306161_3306503_-\|holin	phage holin, lambda family	Q8SBE1	Shigella_phage	6.3e-29	54.2
WP_014071191.1\|3306674_3307079_-	antitermination protein	S5M7R9	Escherichia_phage	2.1e-31	52.4
WP_014071192.1\|3307068_3307713_-	DNA methyltransferase	I6PDF5	Cronobacter_phage	3.8e-83	65.9
3307690:3307707	attL	NA	NA	NA	NA
WP_014071193.1\|3307709_3308327_-	recombination protein NinG	A0A1W6JNX3	Morganella_phage	4.7e-43	57.9
WP_014071194.1\|3308323_3309295_-	toprim domain-containing protein	A0A1B5FPA8	Escherichia_phage	3.0e-108	62.2
WP_014071195.1\|3309291_3310821_-	DEAD/DEAH box helicase	A0A286N2P9	Klebsiella_phage	9.2e-205	67.2
WP_014071196.1\|3310813_3311089_-	NUMOD4 domain-containing protein	NA	NA	NA	NA
WP_014071198.1\|3311563_3312034_-	hypothetical protein	K7PJS5	Enterobacterial_phage	1.7e-61	76.9
WP_014071199.1\|3312059_3312257_-	Cro/Cl family transcriptional regulator	H9C161	Pectobacterium_phage	1.1e-12	51.7
WP_014071200.1\|3312352_3313006_+	helix-turn-helix domain-containing protein	K7PLZ5	Enterobacterial_phage	3.7e-70	58.5
WP_041162262.1\|3313412_3314486_+	RelA/SpoT domain-containing protein	A0A1B0VBT5	Salmonella_phage	4.4e-52	39.3
WP_014071202.1\|3314868_3315228_+	hypothetical protein	NA	NA	NA	NA
WP_014071203.1\|3315269_3316082_+	DUF2303 family protein	NA	NA	NA	NA
WP_014071204.1\|3316168_3317008_+	DNA-binding protein	A0A2H4J902	uncultured_Caudovirales_phage	1.6e-73	55.8
WP_014071205.1\|3317209_3318001_+	hypothetical protein	A0A1R3Y5S0	Salmonella_virus	1.3e-24	57.0
WP_128738906.1\|3317946_3318954_+	phosphoadenosine phosphosulfate reductase family protein	A0A193GZ89	Enterobacter_phage	1.7e-186	98.1
WP_014071207.1\|3318957_3319347_+	hypothetical protein	H6WRY2	Salmonella_phage	9.4e-21	69.6
WP_014071208.1\|3319348_3319915_+	3'-5' exoribonuclease	A0A192Y6E0	Salmonella_phage	1.6e-69	66.7
WP_014071209.1\|3319925_3320111_+	50S ribosomal protein L7/L12	A0A2R2Z2X2	Escherichia_phage	2.6e-13	57.9
WP_014071210.1\|3320094_3321264_-\|integrase	site-specific integrase	A0A2R2Z2Y0	Escherichia_phage	2.3e-195	83.5
WP_014071211.1\|3321718_3323008_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.4e-73	39.6
WP_014071212.1\|3323007_3323949_+	hypothetical protein	A0A1W6JPD1	Morganella_phage	8.4e-07	48.9
WP_000153152.1\|3324062_3324275_+	AlpA family phage regulatory protein	A0A1W6JPE9	Morganella_phage	6.9e-10	49.2
WP_014071213.1\|3324324_3324504_-	hypothetical protein	A0A2H4JB52	uncultured_Caudovirales_phage	4.4e-10	54.2
WP_001118612.1\|3324635_3324812_+	host cell division inhibitor Icd-like protein	Q7M2A7	Enterobacteria_phage	4.2e-05	55.6
WP_014071214.1\|3324804_3325164_+	hypothetical protein	NA	NA	NA	NA
WP_014071215.1\|3325195_3325480_+	hypothetical protein	NA	NA	NA	NA
WP_014071216.1\|3325476_3325866_+	DUF5375 family protein	NA	NA	NA	NA
WP_014071217.1\|3325862_3328535_+	TOPRIM and DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	2.1e-58	34.6
WP_014071218.1\|3328935_3329697_+\|capsid	phage capsid morphogenesis protein encoded in CP-933I	NA	NA	NA	NA
WP_014071219.1\|3329696_3329969_+	ogr/Delta-like zinc finger family protein	A0A2I8TV89	Erwinia_phage	1.4e-07	44.9
WP_014071220.1\|3330292_3331963_+	hypothetical protein	NA	NA	NA	NA
WP_014071221.1\|3332662_3333139_+	WbuC family cupin fold metalloprotein	NA	NA	NA	NA
WP_088201875.1\|3333445_3334366_+	kdo(2)-lipid IV(A) palmitoleoyltransferase	A0A1W6JP29	Morganella_phage	9.8e-77	53.9
WP_099458937.1\|3334706_3334778_+	membrane protein YpdK	NA	NA	NA	NA
WP_014071223.1\|3334845_3336069_-	alanine transaminase	NA	NA	NA	NA
WP_014071224.1\|3336455_3338153_+	sensor histidine kinase	NA	NA	NA	NA
WP_014071225.1\|3338166_3338898_+	response regulator transcription factor	A0A2R2ZGH8	Clostridioides_phage	6.5e-15	25.1
WP_014071226.1\|3338935_3339901_-	glucokinase	NA	NA	NA	NA
WP_014071227.1\|3340105_3341341_+	ion channel protein	NA	NA	NA	NA
WP_014071228.1\|3341341_3343000_-	indolepyruvate decarboxylase	NA	NA	NA	NA
WP_014071229.1\|3343184_3344183_+	aldo/keto reductase	NA	NA	NA	NA
WP_014071230.1\|3344309_3344645_+	DUF2502 domain-containing protein	NA	NA	NA	NA
WP_014071231.1\|3344679_3345918_-	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_014071232.1\|3346268_3347456_+	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_074392908.1\|3347500_3349654_-	EAL domain-containing protein	NA	NA	NA	NA
WP_014071234.1\|3350314_3350671_+	putative DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_128738936.1\|3350693_3351068_+	putative DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_014071236.1\|3351111_3352527_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
3353246:3353263	attR	NA	NA	NA	NA

DBSCAN-SWA_5

4190828 : 4293257

uncultured_Caudovirales_phage(50.0%)

tRNA,integrase,head,tail,portal,terminase,protease,capsid

attL 4213227:4213250|attR 4297686:4297709

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014071964.1\|4190828_4193684_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.7e-141	36.9
WP_014071965.1\|4193807_4194311_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014071966.1\|4194394_4195414_+	NAD(P)-dependent alcohol dehydrogenase	A0A0G2YAX3	Acanthamoeba_polyphaga_mimivirus	1.9e-44	30.7
WP_014071967.1\|4195506_4197153_-	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_014071968.1\|4197290_4198796_+	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	1.1e-82	43.6
WP_128738943.1\|4198775_4199717_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	3.1e-17	36.8
WP_041162137.1\|4200403_4204864_+	glutamate synthase large subunit	NA	NA	NA	NA
WP_014071970.1\|4204873_4206292_+	glutamate synthase small subunit	NA	NA	NA	NA
WP_014071971.1\|4206327_4206795_-	YhcH/YjgK/YiaL family protein	NA	NA	NA	NA
WP_014071972.1\|4206806_4207661_-	N-acetylmannosamine kinase	NA	NA	NA	NA
WP_014071973.1\|4207641_4208346_-	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_014071974.1\|4208350_4209841_-	MFS transporter	Q6JIH2	Burkholderia_virus	1.1e-08	22.7
WP_014071975.1\|4209933_4210827_-	N-acetylneuraminate lyase	NA	NA	NA	NA
WP_014071976.1\|4210949_4211732_-	transcriptional regulator NanR	NA	NA	NA	NA
WP_041162289.1\|4211834_4212332_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	8.6e-27	53.7
WP_014071978.1\|4212337_4212976_-	stringent starvation protein A	NA	NA	NA	NA
4213227:4213250	attL	NA	NA	NA	NA
WP_003860436.1\|4213284_4213677_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_014071979.1\|4213692_4214121_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_014071980.1\|4214411_4215536_-	cell division protein ZapE	NA	NA	NA	NA
WP_014071981.1\|4215725_4216124_+	DUF1043 family protein	NA	NA	NA	NA
WP_014071982.1\|4216295_4217663_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	1.3e-21	26.8
WP_014071983.1\|4217755_4218823_+	outer membrane-stress sensor serine endopeptidase DegS	NA	NA	NA	NA
WP_014071984.1\|4218909_4219848_-	malate dehydrogenase	NA	NA	NA	NA
WP_003860428.1\|4220245_4220716_+	transcriptional regulator ArgR	NA	NA	NA	NA
WP_014071985.1\|4221094_4221358_+	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_014071986.1\|4221464_4221731_+	peroxide/acid stress response protein YhcN	NA	NA	NA	NA
WP_014071987.1\|4221798_4222071_-	barstar family protein	NA	NA	NA	NA
WP_014071988.1\|4222116_4223571_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_014071989.1\|4223659_4225627_-	p-hydroxybenzoic acid efflux pump subunit AaeB	NA	NA	NA	NA
WP_014071990.1\|4225632_4226565_-	p-hydroxybenzoic acid efflux pump subunit AaeA	NA	NA	NA	NA
WP_003860416.1\|4226572_4226776_-	AaeX family protein	NA	NA	NA	NA
WP_014071991.1\|4226955_4227882_+	HTH-type transcriptional activator AaeR	NA	NA	NA	NA
WP_014071992.1\|4228099_4228714_+	YagU family protein	NA	NA	NA	NA
WP_014071993.1\|4228764_4230210_-\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_014071994.1\|4230296_4234097_-	AsmA2 domain-containing protein YhdP	NA	NA	NA	NA
WP_014071995.1\|4234140_4235610_-	ribonuclease G	NA	NA	NA	NA
WP_014071996.1\|4235599_4236193_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_014071997.1\|4236202_4236691_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_014071998.1\|4236690_4237707_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_000913396.1\|4237769_4238813_-	rod shape-determining protein MreB	F2Y0P3	Organic_Lake_phycodnavirus	6.7e-05	22.3
WP_014071999.1\|4239093_4241034_-	RNase E specificity factor CsrD	NA	NA	NA	NA
WP_014072000.1\|4241217_4242192_+	oxidoreductase	NA	NA	NA	NA
WP_014072001.1\|4242269_4243271_+	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_014072002.1\|4243271_4243871_+	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_014072003.1\|4244105_4244558_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_014072004.1\|4244579_4245044_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_014072005.1\|4245054_4246404_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_014072006.1\|4246512_4246755_+	YhdT family protein	NA	NA	NA	NA
WP_014072007.1\|4246744_4248196_+	sodium/pantothenate symporter	NA	NA	NA	NA
WP_014072008.1\|4248207_4249089_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_014072009.1\|4249226_4249967_+	carbonic anhydrase family protein	NA	NA	NA	NA
WP_014072010.1\|4250297_4251263_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_000462905.1\|4251286_4251583_+	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_014072011.1\|4251751_4252516_+	abortive infection family protein	NA	NA	NA	NA
WP_014072012.1\|4252555_4252810_+	hypothetical protein	NA	NA	NA	NA
WP_041162292.1\|4253262_4253601_-	hypothetical protein	NA	NA	NA	NA
WP_014072014.1\|4253609_4254209_-\|tail	tail assembly protein	K7P6V1	Enterobacteria_phage	4.7e-72	73.2
WP_014072015.1\|4254222_4255884_-\|terminase	terminase large subunit	A0A2H4JB64	uncultured_Caudovirales_phage	0.0e+00	97.6
WP_000113647.1\|4255867_4256224_-\|terminase	phage terminase small subunit P27 family	A0A2H4JHS3	uncultured_Caudovirales_phage	5.5e-60	99.2
WP_014072018.1\|4256499_4256943_-	HNH endonuclease	A0A2H4JAS8	uncultured_Caudovirales_phage	6.8e-76	89.1
WP_001549740.1\|4256942_4257236_-\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JD08	uncultured_Caudovirales_phage	9.4e-42	81.4
WP_014072019.1\|4257228_4257567_-\|head	phage head closure protein	A0A2H4JHK5	uncultured_Caudovirales_phage	4.3e-22	47.7
WP_014072020.1\|4257563_4258799_-\|portal	phage portal protein	A0A2H4JFJ9	uncultured_Caudovirales_phage	2.8e-236	97.1
WP_000848270.1\|4258800_4259361_-\|head,protease	HK97 family phage prohead protease	A0A2H4JB68	uncultured_Caudovirales_phage	7.7e-101	98.4
WP_014072021.1\|4259412_4260579_-\|capsid	phage major capsid protein	A0A2H4JED2	uncultured_Caudovirales_phage	1.3e-214	99.2
WP_041162293.1\|4260962_4261565_+	hypothetical protein	NA	NA	NA	NA
WP_014072023.1\|4261642_4262152_+	hypothetical protein	NA	NA	NA	NA
WP_014072024.1\|4262186_4262447_-	hypothetical protein	NA	NA	NA	NA
WP_014072025.1\|4262661_4264026_-	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	4.4e-259	96.9
WP_014072026.1\|4264022_4264391_-	hypothetical protein	A0A2H4JCX7	uncultured_Caudovirales_phage	1.8e-61	98.4
WP_006178882.1\|4264387_4264609_-	hypothetical protein	A0A2H4JBA1	uncultured_Caudovirales_phage	3.4e-12	57.1
WP_128738910.1\|4264601_4264814_-	hypothetical protein	A0A2H4JFH8	uncultured_Caudovirales_phage	7.1e-23	93.4
WP_128738911.1\|4264779_4265850_-	host cell division inhibitor Icd-like protein	A0A2H4JGN8	uncultured_Caudovirales_phage	7.0e-26	31.8
WP_014072030.1\|4265860_4266070_-	AlpA family phage regulatory protein	A0A2H4JB58	uncultured_Caudovirales_phage	3.1e-31	97.1
WP_014072031.1\|4266185_4267028_-	hypothetical protein	NA	NA	NA	NA
WP_014072032.1\|4267024_4268248_-\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.4e-235	96.3
WP_014072033.1\|4268620_4268785_+	DUF2556 family protein	NA	NA	NA	NA
WP_014072034.1\|4268924_4271006_+	bifunctional diguanylate cyclase/phosphodiesterase	G3MA91	Bacillus_virus	4.9e-23	37.1
WP_014072035.1\|4271000_4271648_-	acrEF/envCD operon transcriptional regulator	NA	NA	NA	NA
WP_014072036.1\|4272047_4273187_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_014072037.1\|4273198_4276309_+	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_008502867.1\|4276612_4276834_+	lipoprotein	NA	NA	NA	NA
WP_014072039.1\|4277324_4278350_+	amino acid ABC transporter substrate-binding protein	A0A1B1IT51	uncultured_Mediterranean_phage	2.8e-72	39.7
WP_014072040.1\|4278417_4279599_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_014072041.1\|4279608_4280712_+	ABC transporter permease	NA	NA	NA	NA
WP_014072042.1\|4280719_4281478_+	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.9e-20	30.8
WP_014072043.1\|4287334_4287889_+	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_014072044.1\|4287864_4288113_-	DUF1488 domain-containing protein	NA	NA	NA	NA
WP_041162295.1\|4288109_4288928_-	shikimate dehydrogenase	NA	NA	NA	NA
WP_014072046.1\|4288932_4289505_-	L-threonylcarbamoyladenylate synthase type 1 TsaC	A0A291ATS8	Pandoravirus	1.1e-09	28.3
WP_014072047.1\|4289497_4290052_-	topoisomerase DNA-binding C4 zinc finger domain-containing protein	NA	NA	NA	NA
WP_014072048.1\|4290079_4290553_-	DUF494 domain-containing protein	NA	NA	NA	NA
WP_041162296.1\|4290524_4291649_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_014072050.1\|4291776_4292286_+	peptide deformylase	E3SLL2	Synechococcus_phage	5.1e-19	40.3
WP_014072051.1\|4292309_4293257_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	35.0
4297686:4297709	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_015969

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

55 : 32350

Enterobacteria_phage(42.86%)

head,integrase,terminase,plate,holin,tail,capsid,portal

attL 6944:6955|attR 32369:32380

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014072459.1\|55_310_-	ogr/Delta-like zinc finger family protein	S4TNZ3	Salmonella_phage	1.9e-06	39.4
WP_014072460.1\|349_1486_-	phage late control D family protein	B9A7A9	Serratia_phage	1.8e-160	75.2
WP_041162341.1\|1639_2821_+\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	7.2e-173	75.7
WP_014072462.1\|2821_3334_+\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	2.1e-60	65.9
WP_014072463.1\|3386_3704_+\|tail	phage tail assembly protein	B9A7B2	Serratia_phage	1.7e-20	54.1
WP_032424037.1\|3709_3865_+\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	2.7e-11	63.3
WP_014072464.1\|3851_6818_+\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	1.4e-265	53.6
WP_014072465.1\|6832_7321_+\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	2.4e-66	74.1
6944:6955	attL	NA	NA	NA	NA
WP_014072466.1\|7474_7879_-\|tail	tail fiber assembly protein	U5P083	Shigella_phage	1.2e-26	50.0
WP_014072467.1\|7890_9942_-\|tail	phage tail protein	Q7Y4D4	Escherichia_virus	5.4e-91	81.0
WP_014072468.1\|9953_10481_-\|tail	phage tail protein I	Q858V5	Yersinia_virus	1.3e-73	75.0
WP_014072469.1\|10473_11370_-\|plate	baseplate J/gp47 family protein	A0A0A7NPY5	Enterobacteria_phage	1.6e-103	66.8
WP_014072470.1\|11356_11725_-	GPW/gp25 family protein	A0A0A7NQ90	Enterobacteria_phage	7.0e-34	62.6
WP_014072471.1\|11721_12297_-\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	1.4e-68	66.1
WP_014072472.1\|12293_12932_-	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	3.5e-57	53.6
WP_014072473.1\|12909_13395_-\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	1.7e-59	64.9
WP_014072474.1\|13399_13936_-	DUF2514 family protein	A0A0M4S5V1	Salmonella_phage	4.4e-29	76.8
WP_014072475.1\|13932_14373_-	lysozyme	A0A0M5M782	Salmonella_phage	4.1e-65	83.6
WP_014072476.1\|14359_14692_-\|holin	phage holin, lambda family	A0A0M3ULH4	Salmonella_phage	6.5e-47	90.0
WP_014072477.1\|14701_14902_-\|tail	tail protein X	A0A0A7NV57	Enterobacteria_phage	1.5e-22	77.3
WP_014072478.1\|14901_15426_-\|head	head completion/stabilization protein	A0A0A7NPU2	Enterobacteria_phage	5.4e-40	50.6
WP_014072479.1\|15524_16382_-\|terminase	terminase	B9A7B6	Serratia_phage	3.1e-69	62.2
WP_014072480.1\|16427_17477_-\|capsid	phage major capsid protein, P2 family	A0A0M3ULA3	Salmonella_phage	4.8e-104	51.9
WP_014072481.1\|17500_18337_-\|capsid	GPO family capsid scaffolding protein	A0A0A7NRY7	Enterobacteria_phage	5.4e-98	66.2
WP_014072482.1\|18496_20227_+	helix-turn-helix domain-containing protein	A0A0A7NV54	Enterobacteria_phage	4.2e-270	77.2
WP_014072483.1\|20226_21285_+\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	1.1e-143	70.8
WP_014072484.1\|21721_22360_-	hypothetical protein	NA	NA	NA	NA
WP_014072485.1\|22363_23362_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_014072486.1\|23520_25920_-	replication endonuclease	A0A0M4RTM8	Salmonella_phage	0.0e+00	87.3
WP_014072487.1\|25923_27225_-	phosphoadenosine phosphosulfate reductase family protein	Q8W6P3	Burkholderia_virus	2.1e-40	33.2
WP_014072488.1\|27224_28196_-	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A0M4QWR0	Salmonella_phage	1.1e-137	81.3
WP_014072489.1\|28197_28410_-	hypothetical protein	A0A0M4R514	Salmonella_phage	3.1e-18	66.7
WP_041162342.1\|28495_28726_-	DUF2724 domain-containing protein	A0A0M4S6M9	Salmonella_phage	6.9e-32	86.8
WP_128738957.1\|28715_28919_-	DUF4761 family protein	A0A0M5M1I3	Salmonella_phage	1.4e-15	58.8
WP_014072492.1\|28926_29130_-	hypothetical protein	R9TMQ7	Vibrio_phage	6.4e-05	46.2
WP_014072494.1\|29440_29824_+	helix-turn-helix transcriptional regulator	Q6QID2	Burkholderia_phage	4.0e-24	58.6
WP_014072495.1\|29833_30463_+	membrane protein	NA	NA	NA	NA
WP_014072496.1\|30479_31346_+	BRCT domain-containing protein	NA	NA	NA	NA
WP_014072497.1\|31342_32350_+\|integrase	tyrosine-type recombinase/integrase	Q1I119	Pasteurella_virus	1.1e-105	56.1
32369:32380	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_015963

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015963_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015963_1

145565-145694

Orphan

Consensus_repeat	Method
CTGGGACCATGGTCCCACCTGTCGCAGAGCTGCATTCAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_015963_1

>merge|NC_015963|1|145565-145694|CRISPRCasFinder
CTGGGACCATGGTCCCACCTGTCGCAGAGCTGCATTCAACAGTACGACATCTGCATCCCAGACCGAAACCTCACTGTTCTTTGATGAGACTGGGACCATGGTCCCACCTGTCACAGAGCTGCATTCAACA

>NC_015963|1|1|145565-145694|CRISPRCasFinder
CTGGGACCATGGTCCCACCTGTCGCAGAGCTGCATTCAACA	GTACGACATCTGCATCCCAGACCGAAACCTCACTGTTCTTTGATGAGA
CTGGGACCATGGTCCCACCTGTCACAGAGCTGCATTCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015963.1\|WP_014063951.1\|147903_148434_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_015963.1\|WP_014063944.1\|137250_137733_-\|hypothetical-protein	unknown	unknown	unknown
NC_015963.1\|WP_088201860.1\|146643_147812_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_015963.1\|WP_014063956.1\|153263_153530_-\|hypothetical-protein	unknown	unknown	unknown
NC_015963.1\|WP_014063950.1\|144459_145440_+\|ParB/RepB/Spo0J-family-plasmid-partition-protein	unknown	unknown	gnl\|CDD\|184254
NC_015963.1\|WP_014063959.1\|155250_156432_+\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|182539
NC_015963.1\|WP_014063945.1\|137757_139239_-\|type-VI-secretion-system-contractile-sheath-large-subunit	unknown	unknown	gnl\|CDD\|274538
NC_015963.1\|WP_014063942.1\|134994_136791_-\|type-VI-secretion-system-baseplate-subunit-TssF	unknown	unknown	gnl\|CDD\|274541
NC_015963.1\|WP_014063941.1\|134050_135004_-\|type-VI-secretion-system-baseplate-subunit-TssG	unknown	unknown	gnl\|CDD\|377755
NC_015963.1\|WP_014063943.1\|136783_137197_-\|GPW/gp25-family-protein	unknown	unknown	gnl\|CDD\|226049
NC_015963.1\|WP_041162338.1\|149951_151190_-\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NC_015963.1\|WP_014063957.1\|153647_154436_-\|MipA/OmpV-family-protein	unknown	unknown	gnl\|CDD\|377682
NC_015963.1\|WP_014063946.1\|139228_139735_-\|type-VI-secretion-system-contractile-sheath-small-subunit	unknown	unknown	gnl\|CDD\|377529
NC_015963.1\|WP_014063958.1\|154561_155254_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015963.1\|WP_014063948.1\|141526_142537_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NC_015963.1\|WP_014063960.1\|156523_157669_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_015963.1\|WP_014063949.1\|143293_144460_+\|plasmid-partitioning-protein-SopA	unknown	unknown	gnl\|CDD\|184261
NC_015963.1\|WP_014063952.1\|148438_148708_-\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|226860
NC_015963.1\|WP_014063947.1\|140532_141273_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NC_015963.1\|WP_049796706.1\|151415_152126_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015963.1\|WP_014063951.1\|147903_148434_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.000186182
NC_015963.1\|WP_088201860.1\|146643_147812_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	3.33316e-141
NC_015963.1\|WP_014063957.1\|153647_154436_-\|MipA/OmpV-family-protein	gnl\|CDD\|377682	pfam06629, MipA, MltA-interacting protein MipA. This family consists of several bacterial MltA-interacting protein (MipA) like sequences. As well as interacting with the membrane-bound lytic transglycosylase MltA, MipA is known to bind to PBP1B, a bifunctional murein transglycosylase/transpeptidase. MipA is considered to be a structural protein mediating the assembly of MltA to PBP1B into a complex.	9.28934e-48
NC_015963.1\|WP_014063950.1\|144459_145440_+\|ParB/RepB/Spo0J-family-plasmid-partition-protein	gnl\|CDD\|184254	PRK13698, PRK13698, ParB/RepB/Spo0J family plasmid partition protein.	0
NC_015963.1\|WP_014063945.1\|137757_139239_-\|type-VI-secretion-system-contractile-sheath-large-subunit	gnl\|CDD\|274538	TIGR03355, VI_chp_2, type VI secretion protein, EvpB/VC_A0108 family. Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis].	0
NC_015963.1\|WP_014063942.1\|134994_136791_-\|type-VI-secretion-system-baseplate-subunit-TssF	gnl\|CDD\|274541	TIGR03359, VI_chp_6, type VI secretion protein, VC_A0110 family. This protein family is associated with type VI secretion in a number of pathogenic bacteria. Mutation is associated with impaired virulence, such as impaired infection of plants by Rhizobium leguminosarum.	1.05073e-170
NC_015963.1\|WP_014063941.1\|134050_135004_-\|type-VI-secretion-system-baseplate-subunit-TssG	gnl\|CDD\|377755	pfam06996, T6SS_TssG, Type VI secretion, TssG. This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssG. TssG is homologs to phage tail proteins and is required for proper assembly of the Hcp tube in bacteria.One other member in this family, SciB (Q93IT4) from Salmonella enterica, is thought to be involved in virulence.	6.38385e-60
NC_015963.1\|WP_014063943.1\|136783_137197_-\|GPW/gp25-family-protein	gnl\|CDD\|226049	COG3518, COG3518, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	8.28493e-05
NC_015963.1\|WP_041162338.1\|149951_151190_-\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	4.0507e-49
NC_015963.1\|WP_014063959.1\|155250_156432_+\|two-component-sensor-histidine-kinase	gnl\|CDD\|182539	PRK10549, PRK10549, two-component system sensor histidine kinase BaeS.	4.27099e-63
NC_015963.1\|WP_014063946.1\|139228_139735_-\|type-VI-secretion-system-contractile-sheath-small-subunit	gnl\|CDD\|377529	pfam05591, T6SS_VipA, Type VI secretion system, VipA, VC_A0107 or Hcp2. VipA is a family of Gram-negative bacterial proteins that form part of the type VI pathogenic secretion system. Members have been variously defined as VC_A0107 family, Hcp2 and VipA, for ClpV-interacting proteins. VipB and VipA proteins interact very closely to form the shaft of the pathogenic penetrating needle system.	2.23492e-61
NC_015963.1\|WP_014063958.1\|154561_155254_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.58297e-68
NC_015963.1\|WP_014063948.1\|141526_142537_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	0.000302144
NC_015963.1\|WP_014063960.1\|156523_157669_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	7.7398e-61
NC_015963.1\|WP_014063949.1\|143293_144460_+\|plasmid-partitioning-protein-SopA	gnl\|CDD\|184261	PRK13705, PRK13705, plasmid-partitioning protein SopA; Provisional.	0
NC_015963.1\|WP_014063952.1\|148438_148708_-\|DUF1778-domain-containing-protein	gnl\|CDD\|226860	COG4453, COG4453, Uncharacterized protein conserved in bacteria [Function unknown].	2.80287e-23
NC_015963.1\|WP_014063947.1\|140532_141273_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	1.09107e-22

>NC_015963.1|WP_014063950.1|144459_145440_+|ParB/RepB/Spo0J-family-plasmid-partition-protein
MKRAPVIPKHSVKNAPAEIEQPASVAPAAPMVDSLIARVGAMARGNSILLPVCGREVKFTLEAIPGDTAETASRVWSGNERDQELLTEDALDDLIPSFLLSGQQTPAFGRRVSGVIEVADGSRRRKAAILTSSDYRILVGDLDDEQMMALSRLGNDYRPTSAYERGKRYAYRLENEFGGNVSALADAENISRKIITRCINTARLPKPVVALFIHPGELSARAGEALYKAFTGKEDLLQQLTAQLHEQKKAGVIFEGDEVIGLLTGKLKESSSAKVNLSTRHQFVPGASVLYKGDKVIFNLDKTRLPAECIEKIEGILRELQQNKSL
>NC_015963.1|WP_014063949.1|143293_144460_+|plasmid-partitioning-protein-SopA
MGLMNTLDQCIAAGHEMTKAIAVAQFNDDSPEARKITRRWRVGEAADLIGVSSQAIRDAEKAGRLPHPDMEMRGRVEQRVGYTIEQINHMRDVFGTRLRRPDDSVPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDLHIHAEDTLLPFYLGERDDAAYAVKPTCWPGLDIIPSCLALHRIETELMGRYDDGKLPTEPHMMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDMLRDLLKNVDLQGFEPDVRILLTKYSNNNGSQSPWMEEQIRDAWGSMVLKNVVRETDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALAIWEPVCNEIFDRLIKPRWEIR
>NC_015963.1|WP_014063948.1|141526_142537_-|replication-initiation-protein
MAKENNELPLNLEEVNKTTGEVVKLDVNSASTVQPVALMRLGLFVPTLKSTSRSKTNRKNVTDATEELVQLSIAKSEGYTDVRITGSRLDMDTDFKVWLGIIRSMSECGVKNDTLELSFVEFVKMCGFDSRRSNKKMRDRISNSLFKLASVTLKFQSETKGWTTHLVQSAYYDINEDVVEIKAEPKLFELYHMDRRVLLRLKAIDALQRKESAQALYTYIESLPQNPAPISMKRMRDRLNLTSNVYTQNHTVRKAMTQLKDIGYLDYTEFKRGRSTYFSVHYRNSKLISSTVKVPRKTEEETPEQNYDEVINALKAAGIDPQKLAKALASVKPDND
>NC_015963.1|WP_014063947.1|140532_141273_+|site-specific-integrase
MNNVIPLQNSPERVSILPIAPGVDFSTAVALRRMATSSGVTPAYLLAPEVSALLFYMPDQRHHMLFATMWNTGIRIGEARTLTPESFDLDGLRPFVKVLSEKVRARRRRPPKDEVRLVPLTDANYVRQLQSWMITIRPKRREPLWSVTDETMRNWLKQGIQRAASDGVHFSIPVTPHTFRHSYIMHMLYHRQPKKVIQSLVGHKDPRSMEVYTRVFALELAATIAVPFTGDGRDAADILRSLPPDK
>NC_015963.1|WP_014063946.1|139228_139735_-|type-VI-secretion-system-contractile-sheath-small-subunit
MSNTQHKLDKARPPRVQITYDVEIGDATEAKELPLVIGVMGDFTESSDSLRDRKFVSVDKDNFDEIMSSMMPSAEFQVESVLPGKEGYIPVSLTFNSMEDFSPASIAHQVEPLKQLLELREQLSDLRNRVASNERLKEQLLAIVEKENVSYSEGNQDQTKQPGDDNEQ
>NC_015963.1|WP_014063945.1|137757_139239_-|type-VI-secretion-system-contractile-sheath-large-subunit
MNNERIATLSEGNAVTESYLDQIIDNTQAIRRESDRGRVRLQLNNFLEEVVSGSVVISSNLIGSIEERIVAIDELLSKQISVIMHNTAFQKRESSWRGLQKLIKASVTDNTKIRLLQCNKQDLIKDFRSASDFDQSMLFKCVYESEYGTFGGVPFSAFVGDFEFDNTPQDIDLLEQISHVAAAAHAPFFSAAAPGMLSMNSFTDMSRPRDMAKLFETTDYARWRSFRQTDDSRYVGLTLPKVLGRLPYGTKTIPVESFSFEENIAENESSTDYLWVNAAYELAERVVSSFEDYGWCAAIRGVEGGGLVNALPAYNYISENGERLMQCPTQVAISDRREKELSDLGFIPLVHCKGTDYAVFFAVQSVNKPRLYNSDEANANAKLTSQLPYILVTSRFAHYLKSMVRDKVGSFMSRTECQDYLQKWIMKYVVASDVAGATTKARYPLRDARIEVVDVPGSPGTYRAIAYIKPHFQLEGVNMSLRLVADLPAAASS
>NC_015963.1|WP_014063944.1|137250_137733_-|hypothetical-protein
MASLPNCQFFKISADGKELKGYSKDDEYKNYIEGYSLGSVSSYKSAYGHEFDPVSARILVKPGDVGELYGKFLDKETHKFEVTIVHRTTNGNKPFEHKINVYSGCTIESLAIVAMEDGNTFYDLTFTFGKVSVELNAIGDDGKPEKIGPYVYNVVESKSE
>NC_015963.1|WP_014063943.1|136783_137197_-|GPW/gp25-family-protein
MSLLQLLSDNNPTDESDSYTEENQIKFLLDELKMLFSSRTFFTYIGDVPLVNSSILNYGIDENMVEGNINNQQFDLIEQYIEILLSRFEPRFASVSVAINKVTIFKVYIEISAWYENYPIKLMLDWDIERRRFNLNE
>NC_015963.1|WP_014063942.1|134994_136791_-|type-VI-secretion-system-baseplate-subunit-TssF
MNRILSYYQKELAFLKKHGKAFAEQYPKIARRLGFNDGTSEDPHVERLLESFALLTSRIHQRLDDDMPELTEALLTSVAPQFLRSKPSTCIVEIEPDRNLSSITDKSIIPAGVQLYTRNITEAVCNFQTIYPVTLLPLTVEEANLYFSDDDLLWHLGLKFKVWAGGKIEGEPLRFFLHGQSNVVNIIYTLICSEINKLTLKLEGKIYELKKSDISTVGFEQSDVFIIDDPRVAPIHTLLQNYFFFPSMFHFIDVKLPSEFNATASAVFDIEITFNRMHLTHMLEKLVNTIDAQFFRLNCTPAVNIFPQRAEPIALSENTAEYPVIVDHRKRHTISVWAINNVYIQRKQDNTVITMPVQPLLGIDYSRNEGACDFFWQSFVRGTGNATSPYNMFISFSDRNNSNSKISTLDLVSINLTCTNHNVPNLMVNGHPEGDFESDLPIPALKIRALSKPTRPVSPPEKGEMLWRLVSLLSLNYTLLNGHEGAKVLREQLKLYNWNDNPSITKMINLITYIDVEPVVSRIIKNDPQSLARGISITLTFSDEALNEPEYYLMCCFIERYLALHAPVNSFTKVTTKIEHEEHTLRHWPVRAGKLAWI
>NC_015963.1|WP_014063941.1|134050_135004_-|type-VI-secretion-system-baseplate-subunit-TssG
MDLITIVSKFNFYQQVRTLLHKLRTDELSGTEVLDKKIHFVSTLSLDSPDGQVAKIEHDVAGDSVVVTVNMNGLTGAMGALPTAYSEWLLERHHIYSDKSAKAFLDIFGHRLYCLDYLAWQKNHLYARVEVEREKPLHRANLALTGLLNSRSIFDSEHYAHLFSSSVKSMVNLEVWLGHYYGVTVHITPFVGRWSSVDCNETCLLGMAEQPLGIAPMLGHFRWDIQSYFNITFGPIYESDSYPYLPDGELYQELWNRIFYYVGPGLNFKVFLNIVGGIPSSLGEEQLGRHMCIGSKEKSRLLQVCKPFNFDNMMKGK
>NC_015963.1|WP_088201860.1|146643_147812_+|IS3-family-transposase
MKRRNFSPEFKRESAQLVVDQNYTVSDAAKAMDVGLSTMTKWVKQLRDERQGKTPNASPITPEQIEIRELKKKLQRIEMENEIFKKGYRALDVRLPEQFSIIGKLRARYPVVTLCHVFGVHRSSYKYWKNRPEKPDGKRAVLRSQVLELHGISHGSAGARSIATMATQRGYQMGRWLAGRLMKELRLVSCQQPTHRYRRGGHEHVAIPNHLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPDSRLTMKALEMAWETRGKPVGVMFHSDQGSHYTSRQFRQLLWRYRIRQSMSRRGNCWDNSPMERFFRSLKNEWVPVTGYVSFSDAVHAITDYIVGYYSVLRPHEYNGGLPPNESENRYRKNSNTVASFS
>NC_015963.1|WP_014063951.1|147903_148434_-|GNAT-family-N-acetyltransferase
MDGLKVEIFSEEVEYDLSNFDCGEEYLNTFLTDHLKRQHIGKVLRGYVLVTREDKPRVMGYYTLSGSCFEKEQLPSKTQQKRVPYKNVPSVTLGRLAIDKSIQRQGYGDALVTHAMKVVYLASQAVGIHGMFVEALNDNAKKFYLGLGFVQLKGANSNALFYPTKAIEELFGAQDE
>NC_015963.1|WP_014063952.1|148438_148708_-|DUF1778-domain-containing-protein
MSALKKQRIDLRLNEDDKSMIEEAAAMTNQSISQFMVSTASERAAEVIDQHRRLILNEESWNLVMEAISNPPAPNDRLKRAAKRLQKLE
>NC_015963.1|WP_041162338.1|149951_151190_-|IS91-family-transposase
MSPVLYSAAYIPRPAKLLFTVDDDWNTFLEKFGDSVTPWTRLCIKRMLACGTTEMGVRRYCCSSPDCTHSRFFCQSCKSKACSACSFKATEQWVSQQSHILPDCDWQHITFTMPHLLWPFFSNNWPLLNALFRAATRAMLRWARKQGVEVGIFCALHTYGRQLNQPPHIHLSVTRGGLDIKHGVRRDLFFKKHAVEEIWRGAVIRLLRHSYNLINPGRMPGLEHIRDKKQWQRYLQAQYGRRWKVHFAKKTRGVWRSVKYLGRYLKRPPVSAAKLRHYSGGAVVHNYYDHRTQQYRQQTLTQEEMIGRYISHIPAKHFKMVRYYGFLSNRKRGTLLPKVYEALEMEARKKPEQPGFAALMKEFLRTDPYKCILCGNRLRFTSAQAGRHASELVAERLHAINRKRWLRAQSAG
>NC_015963.1|WP_049796706.1|151415_152126_-|hypothetical-protein
MIDDDADQEPRAPELSQDVQALINNGLEFLDKAREELEASKAKFSVVSFWTAVEILLKVPLVHEHWTLVCSGKKVVRSKYVAGDFQSVTYDETCTRLGDILEKPLPKETMTVFDKVRQHRNRVVHFYHSAFTEADQEQIQKEQADAWFALNRLMRDEWQSIFGAKDSYTWKLAHGETRLLRGSEFYAAVRLRQVKEELDALAKSGKQIAVCDICKQKAQVTQSHSTGSEERTLLIT
>NC_015963.1|WP_014063956.1|153263_153530_-|hypothetical-protein
MKNDILLVILLLGLSAMAHLLLFLYLTPQEIKPLLMQLLHPGRYRGRPYTEKKRVPPEYENAYRNNSYLSVTLDNLHDGMMTLPLPVR
>NC_015963.1|WP_014063957.1|153647_154436_-|MipA/OmpV-family-protein
MITRKLMLYMTCFTLTGLATTARADDASPQQPTLSVGLAGQNLPRYSGSDKQRWQVVPLVQARDGAFFLDTQKGIGYDLQNDSGLYLEHTLGYNLGRSDRDSDWRDGSDKLRGMGKIKATVNTAFAVGWTLTPWLTVEGKATLPLSDSQGVNYQTSATLIPLQTASDTVAFSTAALFGDSRYMNTVYGVSDRQSARSGYAPYQAAGGFYGTDSNLTWSHQFTPNWGALLSVDYTWLDSHAKNSPIVSRRNGTSAMLGVLYTF
>NC_015963.1|WP_014063958.1|154561_155254_+|response-regulator-transcription-factor
MSGKRILIIEDDADAADVLSAYLARESYAVSVAGDGPSGLEMSQRLKPDLILLDVMLPGMNGTEVLAAVRRRGNTPVIMVTAMGDIPDRIGALRYGADDYVVKPYNPGEVVARVQAVLRRVTQAPEASLLRWQGLEVDTVMMTAGVRDEHGELAAIVLTPTEFSLLATLLQAPVRPFSRQHLLEHCLPESDALERSVDTHVYNLRKKLEGAGIHGVLVNVRGVGYRFSQP
>NC_015963.1|WP_014063959.1|155250_156432_+|two-component-sensor-histidine-kinase
MKTLQQQTLWRWICVRILALAIGSVVVIAVCMWLRFAVQSLWNLHRMPPALREEFTLLRAHPEINPARFHEIVDTWWGLRYSDPSIASADWLTVGLLVGVMIPFIVALGLRAARPLSLQFSRLAAAARVVTSGDFSARVTQVDNAPLEMVRFTQDFNAMMQQLARYDRELRASHVAMAHELRSPLTAAIGRLQGMMDGVFTPEPRQLAMVMKQLQLLSRLTDELHLLSLADAGQLTLNKTQTDLTALLRERVAWLGPQAQTAGMTLSLTSREPCPCLADPVRLGQVITIVLENALRYATEGGDVTVSAQATPERARMVFRDRGPGVPADFLPVMFERFTRGESSRARHSGGSGLGLSIARGICEAHGGTIHAAPGETGGLVITVTLPAHHGRK
>NC_015963.1|WP_014063960.1|156523_157669_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MTENFPDFTDCVRQALRHLFTADRLSALLPVVLMLPVCLLLAACGDKPEKPAPPRPVRTVTVPAPSAAGTFLQTGEIRPHDEVTLGFRLDGRLLTRSVDVGDHVAAGQVLGTLENSTSQNQLDSARADLDSTRAAEQLAALNLRRMTQLMPSGAIARVQLDTARSDWQAAASRRRSSEAALNTARENLGWTRLVAPAAGVVTQVSAEPGQVVSAGQTVVSLAVSSGRDAVIDVADPQAFSRPAGGFRVSLLADPTVSVTGTLRDISPQADAQTRTWRVRVTLDNPTPAMALGASVQVGLAGTGPAVMRLPASALTRVQGRPAVFVVDSASRRLQLRPVTLAGFTASDILVSAGVRPGEPVVTAGVSKLREGEVVASGEAGE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015963_1	1.1\|145606\|48\|NC_015963\|CRISPRCasFinder	145606-145653	48	NC_015963	UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS01, complete sequence	145606-145653	0	1.0

1. spacer 1.1|145606|48|NC_015963|CRISPRCasFinder matches to NC_015963 (UNVERIFIED_ORG: Enterobacter soli plasmid pENTAS01, complete sequence) position: , mismatch: 0, identity: 1.0

gtacgacatctgcatcccagaccgaaacctcactgttctttgatgaga	CRISPR spacer
gtacgacatctgcatcccagaccgaaacctcactgttctttgatgaga	Protospacer
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Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

88327 : 130024

Escherichia_phage(57.14%)

integrase,transposase,plate

attL 119668:119681|attR 122020:122033

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014063907.1\|88327_88912_+\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	1.4e-47	51.3
WP_014063908.1\|89379_89931_+	type I fimbrial protein, A chain	NA	NA	NA	NA
WP_014063909.1\|90003_90555_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_049796703.1\|91575_94107_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_167320615.1\|94084_94309_+	hypothetical protein	NA	NA	NA	NA
WP_128738954.1\|94305_94563_+	hypothetical protein	NA	NA	NA	NA
WP_014063912.1\|94690_95299_+	fimbrial protein	NA	NA	NA	NA
WP_014063913.1\|95502_96303_+	EAL domain-containing protein	NA	NA	NA	NA
WP_014063914.1\|96299_96698_+	hypothetical protein	NA	NA	NA	NA
WP_157506106.1\|97394_97559_+	hypothetical protein	NA	NA	NA	NA
WP_014063917.1\|97714_98416_+	hypothetical protein	NA	NA	NA	NA
WP_014063918.1\|98503_99316_+	hypothetical protein	NA	NA	NA	NA
WP_064555910.1\|99774_100353_-	serine/threonine protein kinase	NA	NA	NA	NA
WP_088201860.1\|100575_101744_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.9e-173	94.7
WP_014063922.1\|102000_102612_+\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	2.9e-53	53.9
WP_014063923.1\|103115_104105_+\|integrase	tyrosine-type recombinase/integrase	A0A0K0N6I5	Gordonia_phage	1.7e-05	34.7
WP_014063924.1\|104354_106709_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014063925.1\|106710_108003_-	lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family protein	NA	NA	NA	NA
WP_014063926.1\|108004_109567_-	aspartate aminotransferase family protein	S4W1T5	Pandoravirus	9.9e-13	28.6
WP_041162320.1\|110218_110896_-	hypothetical protein	NA	NA	NA	NA
WP_157506106.1\|111134_111299_-	hypothetical protein	NA	NA	NA	NA
WP_014063914.1\|111995_112394_-	hypothetical protein	NA	NA	NA	NA
WP_014063913.1\|112390_113191_-	EAL domain-containing protein	NA	NA	NA	NA
WP_014063928.1\|113395_114394_-	fimbrial protein	NA	NA	NA	NA
WP_014063929.1\|114384_117117_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_014063930.1\|117177_117948_-	molecular chaperone	NA	NA	NA	NA
WP_014063909.1\|118135_118687_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_014063931.1\|118759_119281_-	hypothetical protein	NA	NA	NA	NA
119668:119681	attL	NA	NA	NA	NA
WP_014063907.1\|119777_120362_-\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	1.4e-47	51.3
WP_014063932.1\|120940_122056_-	hypothetical protein	NA	NA	NA	NA
122020:122033	attR	NA	NA	NA	NA
WP_014063933.1\|122042_124577_-	type VI secretion system ATPase TssH	A0A1C3S747	Escherichia_phage	3.8e-86	29.7
WP_014063934.1\|124596_128031_-	hypothetical protein	NA	NA	NA	NA
WP_014063935.1\|128039_128648_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_014063936.1\|128650_130024_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015968

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_015969

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_015963

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection