CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015967	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17202, complete sequence	0 crisprs	NA	0	0	0	0
NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	9 crisprs	WYL,c2c9_V-U4,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,csx20,cas6,cas2,cas1,cas14j	0	66	0	0
NC_015966	Rhodothermus marinus SG0.5JP17-172, complete genome	9 crisprs	csa3,DEDDh,Cas14u_CAS-V,cas3,DinG,cas3HD,WYL,cas6,cas8b1,cas7,cas5,cas4,cas10,csm3gr7,csx10gr5,csm2gr11,csx19,csx1,cas1,cas2,csm4gr5,csm5gr7,cas14j	0	10	0	0

1. NC_015970

CRISPR-Cas detection and classification

Crispr_ID: NC_015970_1

• CRISPR_ID: NC_015970_1
• CRISPR_location: 35432-35528
• CRISPR_type: TypeIII-A
• Repeat_type: I-A,II-B,III-A
• Spacer_info: 1 spacers
• Cas_protein_info: c2c9_V-U4

Consensus repeat of NC_015970_1

Consensus_repeat	Method
TTTCAATACCAAAAAGGTGCGATTAAAA	CRISPRCasFinder

spacers of NC_015970_1

>1.1|35460|41|NC_015970|CRISPRCasFinder
CACGTCGATCGGCACGGCGAGCCGCCGGGCTGCGGCCTGAG

CRISPR arrays and Neighbor proteins around NC_015970_1

CRISPR arrays

The CRISPR arrays of NC_015970_1

>merge|NC_015970|1|35432-35528|CRISPRCasFinder
TTTCAATACCAAAAAGGTGCGATTAAAACACGTCGATCGGCACGGCGAGCCGCCGGGCTGCGGCCTGAGTTTCAATACCAAAAAGGTGCGATTAAAA

>NC_015970|1|1|35432-35528|CRISPRCasFinder
TTTCAATACCAAAAAGGTGCGATTAAAA	CACGTCGATCGGCACGGCGAGCCGCCGGGCTGCGGCCTGAG
TTTCAATACCAAAAAGGTGCGATTAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072530.1|41244_41751_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072525.1|36217_36772_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_155816011.1|30295_32686_+|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|225829
NC_015970.1|WP_014072532.1|42290_43160_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_027614258.1|38760_39030_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072526.1|36784_37129_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072516.1|26664_27927_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl|CDD|223747
NC_015970.1|WP_014072513.1|24270_25530_+|Y-family-DNA-polymerase	unknown	unknown	gnl|CDD|176454
NC_015970.1|WP_014072512.1|23828_24263_+|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl|CDD|182350
NC_015970.1|WP_014072523.1|32713_34621_+|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|275036
NC_015970.1|WP_155816009.1|25727_26015_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072511.1|22802_23666_-|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl|CDD|198394
NC_015970.1|WP_027614259.1|38233_38605_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072518.1|28626_28866_+|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	unknown	unknown	gnl|CDD|226603
NC_015970.1|WP_014072527.1|37125_37482_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072531.1|41763_42294_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein	unknown	unknown	gnl|CDD|223786
NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein	unknown	unknown	gnl|CDD|226382
NC_015970.1|WP_155816010.1|27874_28282_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072515.1|26104_26668_+|IS607-family-transposase	unknown	unknown	gnl|CDD|239738

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072516.1|26664_27927_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	8.3e-115	379.0	10.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_014072516.1|26664_27927_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.65832e-55
NC_015970.1|WP_014072523.1|32713_34621_+|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|275036	TIGR04183, hypothetical_protein, Por secretion system C-terminal sorting domain. Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber average twenty or more copies of a C-terminal domain, represented by this model, associated with sorting to the outer membrane and covalent modification.	1.68149e-05
NC_015970.1|WP_014072511.1|22802_23666_-|GIY-YIG-nuclease-family-protein	gnl|CDD|198394	cd10447, GIY-YIG_unchar_2, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria and archaea. The family includes a group of uncharacterized hypothetical proteins, mainly found in bacteria and a few found in archaea, with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	1.55628e-34
NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein	gnl|CDD|226382	COG3864, COG3864, Uncharacterized protein conserved in bacteria [Function unknown].	5.77271e-22
NC_015970.1|WP_014072518.1|28626_28866_+|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	gnl|CDD|226603	COG4118, Phd, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	1.01369e-09
NC_015970.1|WP_014072513.1|24270_25530_+|Y-family-DNA-polymerase	gnl|CDD|176454	cd01700, PolY_Pol_V_umuC, umuC subunit of DNA Polymerase V. umuC subunit of Pol V. Pol V is a bacterial translesion synthesis (TLS) polymerase that consists of the heterotrimer of one umuC and two umuD subunits. Translesion synthesis is a process that allows the bypass of a variety of DNA lesions. TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. Pol V, RecA, single stranded DNA-binding protein, beta sliding clamp, and gamma clamp loading complex are responsible for inducing the SOS response in bacteria to repair UV-induced DNA damage.	3.38054e-156
NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	0.000569667
NC_015970.1|WP_155816011.1|30295_32686_+|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|225829	COG3292, COG3292, Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms].	1.66577e-34
NC_015970.1|WP_014072512.1|23828_24263_+|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl|CDD|182350	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit.	7.11148e-46
NC_015970.1|WP_014072515.1|26104_26668_+|IS607-family-transposase	gnl|CDD|239738	cd03769, SR_IS607_transposase_like, Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. This subfamily is composed of proteins that catalyze the transposition of insertion sequence (IS) elements such as IS607 from Helicobacter and IS1535 from Mycobacterium, and similar proteins from other bacteria and several archaeal species. IS elements are DNA segments that move to new sites in prokaryotic and eukaryotic genomes causing insertion mutations and gene rearrangements.	4.4319e-44

Protein sequences

>NC_015970.1|WP_014072523.1|32713_34621_+|T9SS-type-A-sorting-domain-containing-protein
MKQWIISVLSGMITLIAGSLYAQSYTSVEVDNIKGEPGDTVRAAIKVITTAKIAGIQVDITVTDTTVAKLVGFDSDSTVAGDVKASGGIEVTGVSSYAVAAASGVDVTREALLKMGFLILKKGTTAVKLDVVLTVEVNGNINEESHTLHTQVLGNTRPDFTEALADTTIGRNDTLNYRYVATDADGDAVTLFAVELPAGATFDAATGALLWVASVAPGSYTVSIGATDGIDTTTTRANVSVGNSAPVFTNAPADTVSVYQGATLQHDFDVTDVDGDSLWFFVENPPLDPGFSFDAATGEVVYEVPMDAEPGLYSITVGVTDGLDSTLAVLTGRVLSPAAIATVRGTADGEFLTTEGVVTRAMGRFAYIQEGDVAITLFQGSGAFRDAIEGGMIKKGDRLRVYGEVASFHELKEIYPSKYLVVSRNNPLPEAQQVTVAELAANGENYEAELITLYGFELDTKGDTVFSASRNYPIKDASVEDFGLVDLRIPSASDTEWEGQSIPQSPLAFTGVLVQYDAKYQLLAVELGDILSVVANEKTELPKEFAISGLYPNPFAGVLKLRMDMPASMEVKVVLYDVLGREIRVFEEGILPAGAGRELVIKGSDLPAGVYILRVQARGVTGQIYEKVEPVVHVK
>NC_015970.1|WP_155816011.1|30295_32686_+|T9SS-type-A-sorting-domain-containing-protein
MWIGTGGGGLAVFDGTDWTVYNTGNSPLPNDWISALAIDAAGRAWIGTMGGGLAVFDGTDWTVYNTGNSPLPVDWISALAIDAAGRAWIGANWGLAVFDGTDWTIYNTENSTLPADGVTVLTIDAAGRVLIGAHWGGLMVFDGTNWTVYNTENSGLPSDGISALAIDAAGSAWIGTMGGGLAVFDGTNWTIYNPWNSGLPADNVSDLAIDIAGRVWIGTGRGLAVFDGTDWTIYNTGNSPLPAGEVGALAVDAAGRVWIGTGRGLAVFDGTDWTIYNTGNSPLPGDGVGALAVDAAGRVWIGTQGLAVFDGTDWTVYNTGNSPLPVDWISALAIDAAGRVWIGTGGGGLAVFDGTDWTVYNTGNSPLPVDWISALAIDAAGRVWIGTMGGGFAVFDGTNWTVYNTENSGLPSDWISALAIDAGGSVWIGTNGDGLVVFDGTDWTVYNRWNSGLPSYGVNALAADAAGRVWIGRWGLTVFDGTNWTVYTPWNSGLPSNMVYALAVDAAGRVWIGTSDGLAVYQELILPGDVSGDGQVTVTDVVLTLRYIVGLITLSDTQKIAADFNQDGKVNITDAVLILRSIVGGKRFARLEDVRGQVRWGRVIEAAGRKRLPLVVEGASNVYGLELQVALPEGVEFEGVEVPEGWLEAHRVEGGWLHLAAAGLNEAQGEVVVLSLRGVVPEAGLRGVVSLNGVKEERLGDEVPVVFGLEGVYPNPVRGEAAIRYALAEEAEVRLVVYDAVGREVRRLVEGMQEEGEHRVVWDGRGEDGRPLAAGVYFVRLETPEYVATKKIVLVK
>NC_015970.1|WP_014072518.1|28626_28866_+|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin
MSEIGAYEAKTRFSELLRRVEKGECFVITRYGLPVAILKPVPSRRKRKVEEVIRDILEFGRQHSLGGLTIKALIEEGRM
>NC_015970.1|WP_155816010.1|27874_28282_+|hypothetical-protein
MGRGSRKWPVIWIAFRTETDDDAPWNGFRVGSVLEGFLEGLSEGDGIFAVERFEPLGLVEVFQDGAGLRRHGGLLVEVVGGEYYSPKFLIFLHLLPDKISVSLTGSIAGASNWLLDIERFVSGESLRRAPEGCER
>NC_015970.1|WP_014072516.1|26664_27927_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MNVHQAFRYELAPNVEQRRALAQHVGAARFAYNWGLEQCLKALEAGERIPSAVELHRAWNRWKRAHAPWWVEVSKCAPQEAFRDLERAFRSWREGRAGFPRFKRKKSLDDNKARFTGAIRVFARHIQLPRIGKVRSKEKTDRLLTLLSAGKARILSATISREADRWYVSLTCEVERPDPEPKEVRSEHDVVGIDLGLSAFAVLSDGTRIEAPRPLWKALRLLRRRSKALSRKQNGSNNYRKATLRLARLHRRVRNIRRDFLHKVTTELARTKPVLVIEDLNVKGLIRGRLSRSVADVSWSEFRRLLEYKCHWYGSRLIVVDRFFPSTQTCAQCGTAGRKLPLSERTFRCEQCGLELDRDLNAALNLWRYGLAHLTGPTGSSPGSDACGDSSDGGTASGGRSTSHGSRKQEVAGHLDCLPD
>NC_015970.1|WP_014072515.1|26104_26668_+|IS607-family-transposase
MKLSDWARKHGVSYKTAWKWWKAGILPVRARQLPTGTILVEEEAVPEAHGEVVIYARVSSAEQKGDLDRQVARLVGWATERHLRVARVVTEVASGLNGRRRRLRALLADPRVAVIIVETRDRLMRWGFDLVEAALTAQGRRILVVDDREVEDDLERDVLEVLTSLAARLYGRRSARRRARRALEAMQ
>NC_015970.1|WP_155816009.1|25727_26015_+|hypothetical-protein
MVRARVRAHLEALQARFPELLGGCAIREFPGADYAWRLFVPKSVWAEVVRRLAEDIDYDNFKAATARRQGLDGAAYVEALHAVWRTMLGLQRQQL
>NC_015970.1|WP_014072513.1|24270_25530_+|Y-family-DNA-polymerase
MPGAIALVDCASFYVSCERVFDPSLRGVPVVVLSNNDGCVIARSEEAKALGIAMGTPYFQIREKLEREGVRVFSSNYALYGDMSRRVMAVLRSFSPHVEVYSIDEAFLELPRASEEELRSEALRIRERVGRWTGIPVRVGVGLTKTLAKLASERAKAVPEQVLALMRPEHIEAVLEETPVEEVWGIGRRHAARLEALGVRTARQLRDLPDRWVRRHLSVTGLRTVWELRGISCLPLELAAPPRRTLVRSRSFGRAVTDLMELREAVTMHAARAAEKLRALGLAAGALVVFVSTGAYGRGPHYSGSQLVGLRLPSNDMRMLARAAWEGLRRVYRADCAYRKAGVLLLDLVPAGGVQGDLFAALDERSRSLMRAVDALNRRWGGETIRLASAGFARPWDMRQQRRSPRYTTSWAELPVVRA
>NC_015970.1|WP_014072512.1|23828_24263_+|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MSTRVVEVVPVRIGEPLRLPLLLSRVPAGFPSPADDYIEEALDLNELLIRHPAATFFMRVEGDSMIEAGIHSGDLLIVDRAIEPRPGHVVVAAVCGELTVKRLKLHEGRLCLMPEDGSHEPLPIREEMEVVIWGVVTCVIHPLV
>NC_015970.1|WP_014072511.1|22802_23666_-|GIY-YIG-nuclease-family-protein
MSKKRGFSVRIFIPEGDPEGLRLIEKSNWNGQGVVFPRTQFLEARKRPELQRAGVYVLWGPDDSSHLPRLYIGEGDVVAHRLEQHYRQKEFWTHAAVFTSKDENLNKAHVQYLEARLIQMASQARRALLDNANNPQRPSLSEPDQADAEAFLADMLLCLPLVGANFFEAAKKEDARSPELFLRAKGIEARGFESTEGFVGLKGSQAVKEEVPSIGSSLKELRRTLLEQKVLQEEADVLILTQNYAFSSPSAAAGVLLGRRANGRIEWKDERGRTLKEIQESLFNNPS
>NC_015970.1|WP_014072525.1|36217_36772_+|hypothetical-protein
MQTQQQQTMVGTIIADPVAPKRLLINTSNGLYYFRPASVRIGSVIRESIAQKGHATAYVDAAYRVFVTQRDGRRIELGLCLGWNRRPFDPLRPRQFGPITAISKAGRYTLYMKELYQAVYKTQIQGGDSSNILAVLPLLDPELNVDGLHVNYTGDDPIKAELAFELTLLTALLPTENPGAQLSK
>NC_015970.1|WP_014072526.1|36784_37129_+|hypothetical-protein
MKTAFQFALSGSYPEIGLALERILLETLEKLATERDAEVIHHEDLGTYLITSDARDVIEAMDRVEEVTSRFLGRIGEEGVHLSVHVPGATVGLELFGEARRREAPVNLVDILRL
>NC_015970.1|WP_014072527.1|37125_37482_+|hypothetical-protein
MKYDPPVTYQILLVIYGQSRNISLARQLEASEFMAMPVGPHLVAVRHVELEAYAAYSRLEAMRREVRARLEQAGYSGFLRWEPVLHIDVMRRIEPVEDDPKQWAYEILRKFFNKQPDP
>NC_015970.1|WP_027614259.1|38233_38605_+|hypothetical-protein
MRRAQLEMDEIREVVIRELTALPGQRRLSESEAEVEIHPSGFDYYDSMFIVNDVLFHYGFLAVGGHHLPYGTCLWWREDGVMIRMRTDGETFNPMTQLEVLVPLIFPTYAEARRGEFVLESDG
>NC_015970.1|WP_027614258.1|38760_39030_-|hypothetical-protein
MTHDGHAAHVHRIELPGPQIDQDVVLLQRRLNSFGLADARRTQDEGGNAKGAKLPDDVGKTPDVHNVELLHGFTWDRGSDEKGMLSREI
>NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein
MASEPDEESQVVWSRPDFWPREGKGIIVFEELNTAPPSVQNTLLQPFGAPPGADRYVGPHRIPRTFYLCATGNRREDHAHVVALSSALRGRAVIINIPGPNLESWTTWAAEHGVEPAVVAFIRFRPDLLYQPPPAHDETAPFPSPRAWARFVSPLVARGFTTPEMLAAAVGEEAASEFLAFLQEIDSMPDVDRLLARPDELNPEALSLSVRYAIVSALIHRVVSNPKLLAQAAAVAVHFEPELAAVFLSTLIRLGFQTQIFGLRVAHDWVKQHGKLLKI
>NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein
MSIVKARLTKEQALEIRRTLLHLHARMPFWAALVRHTSVVASRAVPTAAVTPADVVLVNPEYFFGLTTGQRIFLLAHEAAHLALRVFERLGARNRLVWNVAQDLLINELVLTDFKQRFKTGDVPPGALLLRQSVSELTSDQLYEMIMHLADEAGLELEGARHASAGRRLCAQHPDIARELRERILPFLERYTSDLLEEAPEDGKVLIEGEQDGGSWEFRVRRALAHSRLHGTQARGAEIFARVATRPRVHWRLPLAAAIRQLAARELKLDYTFMHPNHRRMQGGEVVLPTMTGARGRAVFAVDTSGSMLTLMPDGEHSYLEQALAELDSARRQFQLEVYLINCDANVYVSGWIQPYEPLPEPKGGGGTSFVPVFQHIEERKLRPNFVVVLTDGEGTYPETPPPYDVIWVVFGDRTPPFGQVIRVEL
>NC_015970.1|WP_014072530.1|41244_41751_+|hypothetical-protein
MKLHVAGMGYVPVPEKLQRKLLRAAVRTPRVASWLYTVQSGLGLSRAQIEELLERAAELPVGTLRTVLARAGALGIDLLRRMLDDRKRLHVISQLPPSVYLRVHGLAFDTLEKVLHRYGRPRRWVVEQSPDRAVDGRALRNPCGPHGRGHGLCGPVRAAHRSGIGVRH
>NC_015970.1|WP_014072531.1|41763_42294_+|hypothetical-protein
MKLRIAGVGHVPLSGQVSRELLQLAVRAPRAVRWLLETQRHMEGRLRRADALPFLERVLALPARDLAYFMTGVHPSMVLCLLHAVLERESCYRVFRSMPRPVLRRYFPVLYNPGDVDAADAVLARRGKPHRWRIVYNTEPLVKAARSTEVQPLYALLMEYPESRVFVFNSQSVELS
>NC_015970.1|WP_014072532.1|42290_43160_+|hypothetical-protein
MTPLLRPTRRWKFTPDRQQRRLLRDLADQTGTHGIALALVAVPQDAPLSAERYLEVLSNESARQRYREILRRKHRPRCLAYSIHLGPDVSYDAAALHHKHVCWRVFKTGDGPELREAQRYQELEQRLVHELLKVPTYGELAQVVRGAFRRSFERSDQVFRERGFQLLDRVPETLEPVLEGYRYRVLSRFVDVLDHIQDDQLLRMRSPSLGAPGTQERIHAVMQRYRSAVLLHVEHRGFALVAVSGRVAWSLSYPDASIAPLTRCFGVHYKQFARVLEDMTGMHEVDFPF

Crispr_ID: NC_015970_2

• CRISPR_ID: NC_015970_2
• CRISPR_location: 46177-46632
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: c2c9_V-U4,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1

Consensus repeat of NC_015970_2

Consensus_repeat	Method
GGGTCATCCCTGCGCGCGCGGGAGTCGG	PILER-CR
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CRISPRCasFinder
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CRT

spacers of NC_015970_2

>2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CAGGTGCGCCCCTACGCGGAGGTGATCAAGAAG
>2.2|46266|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CCAGAATCAGAAAACGCAGCATCTGAGGCGATG
>2.3|46327|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CACGACCGGTGAGCACGTCGAGGATCCGAAGCG
>2.4|46388|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT
TCAAGAAGGTGTTGCCATAATGAAACCGCGATA
>2.5|46449|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CTGTCCACCTTCTGCGGCCGAAAAAGACGGCGG
>2.6|46510|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CTTTGCGCTGATCTTTACGGCCCGCGTGCTTTT
>2.7|46571|34|NC_015970|CRISPRCasFinder,CRT
TTACACGCATGGAGGCGTAGCCGCCCGGCGGGAG

CRISPR arrays and Neighbor proteins around NC_015970_2

CRISPR arrays

The CRISPR arrays of NC_015970_2

>merge|NC_015970|2|46177-46632|PILER-CR,CRISPRCasFinder,CRT
GGGTCATCCCTGCGCGCGCGGGAGTCGGCAGGTGCGCCCCTACGCGGAGGTGATCAAGAAGGGGTCATCCCTGCGCGCGCGGGAGTCGGCCAGAATCAGAAAACGCAGCATCTGAGGCGATGGGGTCATCCCTGCGCGCGCGGGAGTCGGCACGACCGGTGAGCACGTCGAGGATCCGAAGCGGGGTCATCCCTGCGCGCGCGGGAGTCGGTCAAGAAGGTGTTGCCATAATGAAACCGCGATAGGGTCATCCCTGCGCGCGCGGGAGTCGGCTGTCCACCTTCTGCGGCCGAAAAAGACGGCGGGGGTCATCCCTGCGCGCGCGGGAGTCGGCTTTGCGCTGATCTTTACGGCCCGCGTGCTTTTGGGTCATCCCTGCGCGCGCGGGAGTCGGTTACACGCATGGAGGCGTAGCCGCCCGGCGGGAGGGTTCATCCCTGCGCGCGGGAGTCGGTA

>NC_015970|2|1|46177-46570|PILER-CR
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CAGGTGCGCCCCTACGCGGAGGTGATCAAGAAG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CCAGAATCAGAAAACGCAGCATCTGAGGCGATG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CACGACCGGTGAGCACGTCGAGGATCCGAAGCG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	TCAAGAAGGTGTTGCCATAATGAAACCGCGATA
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CTGTCCACCTTCTGCGGCCGAAAAAGACGGCGG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CTTTGCGCTGATCTTTACGGCCCGCGTGCTTTT
GGGTCATCCCTGCGCGCGCGGGAGTCGG

>NC_015970|2|2|46177-46632|CRISPRCasFinder
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CAGGTGCGCCCCTACGCGGAGGTGATCAAGAAG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CCAGAATCAGAAAACGCAGCATCTGAGGCGATG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CACGACCGGTGAGCACGTCGAGGATCCGAAGCG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	TCAAGAAGGTGTTGCCATAATGAAACCGCGATA
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CTGTCCACCTTCTGCGGCCGAAAAAGACGGCGG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CTTTGCGCTGATCTTTACGGCCCGCGTGCTTTT
GGGTCATCCCTGCGCGCGCGGGAGTCGG	TTACACGCATGGAGGCGTAGCCGCCCGGCGGGAG
GGTTCATCCCTGCGCGCGGGAGTCGGTA

>NC_015970|2|1|46177-46632|CRT
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CAGGTGCGCCCCTACGCGGAGGTGATCAAGAAG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CCAGAATCAGAAAACGCAGCATCTGAGGCGATG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CACGACCGGTGAGCACGTCGAGGATCCGAAGCG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	TCAAGAAGGTGTTGCCATAATGAAACCGCGATA
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CTGTCCACCTTCTGCGGCCGAAAAAGACGGCGG
GGGTCATCCCTGCGCGCGCGGGAGTCGG	CTTTGCGCTGATCTTTACGGCCCGCGTGCTTTT
GGGTCATCCCTGCGCGCGCGGGAGTCGG	TTACACGCATGGAGGCGTAGCCGCCCGGCGGGAG
GGTTCATCCCTGCGCGCGGGAGTCGGTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072530.1|41244_41751_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl|CDD|223747
NC_015970.1|WP_014072532.1|42290_43160_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	cas10	cd09680_cas10_CAS-III	gnl|CDD|274209
NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein	unknown	unknown	gnl|CDD|227209
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	gnl|CDD|187794
NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein	unknown	unknown	gnl|CDD|372298
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl|CDD|187793
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	csx1	cd09741_csx1_CAS-III	gnl|CDD|187872
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl|CDD|367635
NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein	unknown	unknown	gnl|CDD|379423
NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224586
NC_015970.1|WP_027614258.1|38760_39030_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_027614259.1|38233_38605_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_081472095.1|43246_43588_+|transposase	unknown	unknown	gnl|CDD|379129
NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein	unknown	unknown	gnl|CDD|370692
NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein	unknown	unknown	gnl|CDD|223786
NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein	unknown	unknown	gnl|CDD|226382
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_015970.1|WP_014072531.1|41763_42294_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	1.3e-68	226.6	12.3
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	cas10	cd09680_cas10_CAS-III	7.8e-88	290.3	0.0
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	csx1	cd09741_csx1_CAS-III	2.9e-32	106.7	0.0
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	2.6e-44	146.5	0.0
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	4.4e-34	113.0	0.0
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	1.8e-26	87.6	0.0
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	4.4e-73	240.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.35007e-21
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	1.91901e-64
NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein	gnl|CDD|227209	COG4872, COG4872, Predicted membrane protein [Function unknown].	0.00993409
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|187794	cd09663, Csm4_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	2.9537e-29
NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein	gnl|CDD|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	1.87311e-10
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.2545e-28
NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein	gnl|CDD|370692	pfam09787, Golgin_A5, Golgin subfamily A member 5. Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.	1.09581e-05
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	9.83611e-36
NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein	gnl|CDD|379423	pfam14020, DUF4236, Protein of unknown function (DUF4236). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 69 and 402 amino acids in length.	1.49154e-06
NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein	gnl|CDD|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	7.40216e-22
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	gnl|CDD|187872	cd09741, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	8.67464e-26
NC_015970.1|WP_081472095.1|43246_43588_+|transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.00172e-05
NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	0.000569667
NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein	gnl|CDD|226382	COG3864, COG3864, Uncharacterized protein conserved in bacteria [Function unknown].	5.77271e-22
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.59974e-87

Protein sequences

>NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MLRAYRLELEIASERKRRFLHQHFGAARFIYNWALRLVREKGFEFFKQGKGGIGKRILYYWREERDKVAPWHHEINAHTFNGAVLDLGRDLKHHSPSQLRGRSRNRHRSAHFYGIKLQHIGRRSIKLPGSRAGEFRGGVYLKVKKGTGKLYEDIQQGRIRTIKRITVSERAGRYFASVLCEVQEPEPLPCTGRVCGLDVGISSIVTVALSDGRIIKQGNPQWLAKKLRRLRRIQRSLARCKTHFPRDPGFKSLHILRRDGEVLAVFPLMWRRQNGELVPEVGDDVRILAEGVASYALLSRAPDRLEKPYRLTVGGQGSGANIELSTMRIRQGHPVRVVHLSVDRSHTMERRRKTLARAHYRVSVAREDFWHRLSTWLVRNCDVIVVESLSIKGMLRSGRFSRHIADAAWGTFFQMLQYKCERYGRTLLRVERSYPSSKKCSRCGKIRKALSLSERTYRCDQCGLKIDRDENAALNLMKLGLAHLTSPTARLAGSDAGGGTIAGGAAACT
>NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein
MGGGSHQWASEAADAAADKETLQDFVHRFTRAEAWVSPDAWRGYAALARAHEVVRHGQGEWARDGRREVHVNTTEGMWTEVRDFLRPFKGVHKRYLPGYLAMAEFCRNLKRITPAFIAALVRLPCAHFL
>NC_015970.1|WP_081472095.1|43246_43588_+|transposase
MTHNGHASSPDRRGRPRRADREILEAIVWILHTGAPGAKLPAQVHLPRSLPSVEPKRHPPTNCWPKNATNRASSNFRRAWLIYKKCAQGRRTRAAMKAGVMRFRLRQNSAIAR
>NC_015970.1|WP_014072532.1|42290_43160_+|hypothetical-protein
MTPLLRPTRRWKFTPDRQQRRLLRDLADQTGTHGIALALVAVPQDAPLSAERYLEVLSNESARQRYREILRRKHRPRCLAYSIHLGPDVSYDAAALHHKHVCWRVFKTGDGPELREAQRYQELEQRLVHELLKVPTYGELAQVVRGAFRRSFERSDQVFRERGFQLLDRVPETLEPVLEGYRYRVLSRFVDVLDHIQDDQLLRMRSPSLGAPGTQERIHAVMQRYRSAVLLHVEHRGFALVAVSGRVAWSLSYPDASIAPLTRCFGVHYKQFARVLEDMTGMHEVDFPF
>NC_015970.1|WP_014072531.1|41763_42294_+|hypothetical-protein
MKLRIAGVGHVPLSGQVSRELLQLAVRAPRAVRWLLETQRHMEGRLRRADALPFLERVLALPARDLAYFMTGVHPSMVLCLLHAVLERESCYRVFRSMPRPVLRRYFPVLYNPGDVDAADAVLARRGKPHRWRIVYNTEPLVKAARSTEVQPLYALLMEYPESRVFVFNSQSVELS
>NC_015970.1|WP_014072530.1|41244_41751_+|hypothetical-protein
MKLHVAGMGYVPVPEKLQRKLLRAAVRTPRVASWLYTVQSGLGLSRAQIEELLERAAELPVGTLRTVLARAGALGIDLLRRMLDDRKRLHVISQLPPSVYLRVHGLAFDTLEKVLHRYGRPRRWVVEQSPDRAVDGRALRNPCGPHGRGHGLCGPVRAAHRSGIGVRH
>NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein
MSIVKARLTKEQALEIRRTLLHLHARMPFWAALVRHTSVVASRAVPTAAVTPADVVLVNPEYFFGLTTGQRIFLLAHEAAHLALRVFERLGARNRLVWNVAQDLLINELVLTDFKQRFKTGDVPPGALLLRQSVSELTSDQLYEMIMHLADEAGLELEGARHASAGRRLCAQHPDIARELRERILPFLERYTSDLLEEAPEDGKVLIEGEQDGGSWEFRVRRALAHSRLHGTQARGAEIFARVATRPRVHWRLPLAAAIRQLAARELKLDYTFMHPNHRRMQGGEVVLPTMTGARGRAVFAVDTSGSMLTLMPDGEHSYLEQALAELDSARRQFQLEVYLINCDANVYVSGWIQPYEPLPEPKGGGGTSFVPVFQHIEERKLRPNFVVVLTDGEGTYPETPPPYDVIWVVFGDRTPPFGQVIRVEL
>NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein
MASEPDEESQVVWSRPDFWPREGKGIIVFEELNTAPPSVQNTLLQPFGAPPGADRYVGPHRIPRTFYLCATGNRREDHAHVVALSSALRGRAVIINIPGPNLESWTTWAAEHGVEPAVVAFIRFRPDLLYQPPPAHDETAPFPSPRAWARFVSPLVARGFTTPEMLAAAVGEEAASEFLAFLQEIDSMPDVDRLLARPDELNPEALSLSVRYAIVSALIHRVVSNPKLLAQAAAVAVHFEPELAAVFLSTLIRLGFQTQIFGLRVAHDWVKQHGKLLKI
>NC_015970.1|WP_027614258.1|38760_39030_-|hypothetical-protein
MTHDGHAAHVHRIELPGPQIDQDVVLLQRRLNSFGLADARRTQDEGGNAKGAKLPDDVGKTPDVHNVELLHGFTWDRGSDEKGMLSREI
>NC_015970.1|WP_027614259.1|38233_38605_+|hypothetical-protein
MRRAQLEMDEIREVVIRELTALPGQRRLSESEAEVEIHPSGFDYYDSMFIVNDVLFHYGFLAVGGHHLPYGTCLWWREDGVMIRMRTDGETFNPMTQLEVLVPLIFPTYAEARRGEFVLESDG
>NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein
MKTLTFADWDTVFAYLGHLARQERLLVILDEFPYLCEAAPELPSIIQRFWDLEEQHSRLFLVRCGSQPGFMEREVLGERSPLYGRRTGQLRLQPLDYREAGQFFAGYGWRDRLLAYGMLGGMPAYLQRFEPKRSLRENLLQEMLSAQGYLYEEPRFLLRMELRDVRVYASILGAIASGCTRLNEIAQRVGVAAHAVSKYLSVLQELGLIARAVPFLARAPQRSKQGRYHMLDPFLRCWYRFVYPHATLIEARQGELVYERFIRPQLDPYMGGIFEEVARAYMERYAAAELGVPPVVRTGREWAGDFDLDLMAEHADGSWTIGECKWTRRPVGVEVLRELRSRWERLGRRQRLPERVRYFIFSSGGFTPGLLRQRDGAIRLLGLAELFGEVSTTAEG
>NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MPVTLKLITRSPLHIGSGHELESFEYIIHDGFFWRLDINRVTAFLLDEIGEEALEQFSSWIEWKTDRLADARNNREQAEIRRSLTLRTFVRGELGRPDLDARLLQQLQSRSRYAMRTSFSEFRQLVREQLKDPDGRLYIPGSSLKGALRTCLLYQVLVEADEKTHRRWLAELRDSLGRAGRSLNRRERVFFSRWLEEDVFYCGVRKKGKVSWRDAQFDLLKFLRISDSSSVAADEIGVVTDVEIFLPGAEPQPQAPPVEALEAGAELQAQVGFDVSFFREAHRLLARGEKGMGTDIWIGLPEKFQRLYGLTLEEAAAMEAEELERRLLERVRKAARNFGRALKAFEKEWCRRAERGSTLQQARRLQRFYDELPDDCLRLGWGSGFAAVTVYLALREKPAWKEPLQNLLHRLFSLKEREDLLQTFPTSRRMAIDGEGTMVEEPMGWVELEWPWSATEAAATTEEEAAEDESDLWVDQIGPNSQDIIAEVVDNSRAPFTIRIFVRGLENERFPCGGASHRAIEVGQRIRVKVSQWNKKAGRPTMFSVQSIRV
>NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MTFQAVYLYPRSSFRTPLRSDTLWGLLVVALRVVAGDREADAFIEACEQGRPPIRLASAFPFVQEQSADGRPVFRHFFPRPVLPPPLLEPSQADARVVFEQMKQGKKVRRIRWLPQELFERVLRGELDEAGLQQELLQQEQSGARKRWPVLLTQDNLHTSIDRLTGTTRQENGAGQLFYSHEYYMKRGQGLFFLVEGEVARILPALRYLHHVGWGGDSSVGKGHFDWELRELELRVPEKPTHRLLLSLYSPTRAELDHIRQHRDRTFYQLERRQGYAGAHRLPGRAYLKRPLYMLSEGSLVPDPGRPLLGAVHTVMEADGVRVRHSGLALDLPARVGLS
>NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MAGFLGNIILKGKMECLTGLHIGGSKEKFEIGGVDQPVIRDPATNYPYVPGSSLKGKMRALLSFALGKAHEDPNFRSFDPNCPLQRVFGTSAESRNIGPSRLVVRDAFPDEATIRMWENLDTELLYTEIKAENSVDRLTSAANPRFPERVVRGSRFNVEFVFSVYESQDADYFRYVIEGLRLLEHSWLGRSGTRGYGQVKFKLTEPIIVTLDDYLEGTEAYRKASRSHEEMTFDLETADFNESRFNQIKQQFLQIAEKLATNQA
>NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2
MNIPGDLAKLKPEEIDSLANEMGRKYAQNVKTAQVRNVFAHINRMRTRMRRGQGIGPEMRRDLVMLKPRLAYAGGRQREVRPMSDDLRQAVDAVLNSENFEQALRNFFDLVEGIVAYHKYHGGKEN
>NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1
MDRSQIEYLGGLLHAIGLLEQLGREQFDAPGISSLQFTEQLLQHCPAFAPHAEAIREAVRQAADALPAEPPPSWLEPLLQRVRLPGHPEPTGGRVFPPRSLSDGVVYPVAPEAVGDGREACRKLWQDLQAEAVRTLQGIEDVGAALETLYTLLEKYTSYIPAPAVQARGVSLFDYSRVTAALRLCRTRAEREPAVLLVKGDVSGIQSFIYRELRGDETENPAQLLRGRSFFVALLARTVVRHLQRLFQLPDGCVLYSSGGHFVMLLPNTEDARQRLDEADRSINQALFRELNGAIQLVLAHAEADARTIEHDPSEALYRLEETLQIAKLRKGWSVLETLVGQPIGETPALPKLNPVGQALPYTDYLIEVPELPASEVPEGTRTELALSGFETTWLFVEEEALEPVLRRLGARSATVFNLRTTKIPAVAVARRTGYRLMPAGVYVPMTEASESRRPLMFEELAAIESANYPLLGFLRMDVDNLGALFVVGLREAFGEHRFGLHRTAALSRELDRFFGAHVNTLARGLDVYLVYAGGDDLFAVGSWVRVLRFARSIREKLREYCGDNPSVTISAGLSIHKEHFPITVAADAAGEEEERAKQAGKNRISLFETPVAWEQLRHLVDELAEPLLQAIIDETLPEEERVPRTFVHTLLRYSREVLDEDGRVDLGALARLNHLLHYTFARRNVREEMLQQAPDRPLVRLVQGFLLLERPDRSEWFRTFVIPAAYVLLKTRKQRD
>NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase
MATLGEQPQVVTLTLDLLAARRVTFDELVLFHTEPHYPALQRALQRLETELAQWPAYRELTVRRVLFRDEAGRPLTDVRADAEARQVYRILFREVLEVKRQRRPLHFLIAGGRKVMAAYGMAVVQLLGEAGDQVWHLISEGELLASGRMHPEPGDRVHLVPVPFLRWSALPPAATRLAVTGDPFEAMRLHEAWLDEESRRQRAWFLLHELTPAERTLLVALARTGASNSELARMLKRSPKTVANQLATVADKYRAFAGLADEVPLSRAELVAHFAPVLDRIEDPCGIDTL
>NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein
MPLHLYKTFRLGPVRLTISHRGIGLSVGTRGLRIGRTPSGRPYIRLGRGHWRLEKRGR
>NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein
MPQPAPEAFGEPSPPAPPEVPDWIADDGLLRDEGVIVGRALSTDPPAPNDGPHHWKLETIRAYYDERRAPLRAQLEAAHRQLERLQRREAVLREDLERHERALAALAEVEPRLPLTGRNLVLSVMLTVVCALTPLVLAELLPPDRFDHPMAVALALSLFGLFAVFQGRSLLVAADARLSGAPARPERWKLYAMEVLPPLAVALLIAVFVHRPEQGWFPTLAIGFAVLLLLLIPGRLLMSLLARTLPELSGWWRMFVHRRRLRRHHRQAAAALRRELEALAGLRAQLEDETIPQIQRKLAFLDARCRRKEALFRSEMELARRRNLLRARHESNGQMHTVSS
>NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein
MLAILRRKLRAEAPDTPRFTLPLPVGTEEPDPNSPHLYGQYDGGLAIDNDAFAEFLQAATRREHLSERIATLQKQREQLQEQLQRAEAAQISAQTLPERLQALERALPEARQRLEQVRRQREQCEQELQALRRSPEVPSLVQVLMYGAAGVAFLVGDIIVSKEIVAQVLYLPLEYERWLFALGLACITFVLKVAYDRLVELPFWQHIRRRFEVVILSISALALITLVFMGALRTQEIQRQHLLRSTEQTVWSLEAESPSVQQQIPTPDNTVLLVTFILSAVMFATAGAVCFSTAHTHARGYFHVYRPLREAYDALTVQEQNATRRLETLEESLTADREELARANATLALVGTPEMLRQDLKQIDEHIAGLQEQLADLLSEQRRASYRSGRERALQYRRLLTEKPAEDEVAEAPEESPAEDETGESMAASGEISSDADQEAIPLGSEENGTTLPETAHPMAIDGAPDGTADLPEGITDPDEAGAGHSAEPDEAGAESTAVVIGNIETATASTTEGADATEGASATEAASTFEGGDNESDGLAGTPDALSLEAGDAVVGDESAAAGGDSSVRAATPRSRRERGVRHGLRRPFLDIRDEILDLTA

Crispr_ID: NC_015970_3

• CRISPR_ID: NC_015970_3
• CRISPR_location: 50241-50807
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: c2c9_V-U4,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1

Consensus repeat of NC_015970_3

Consensus_repeat	Method
GGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRISPRCasFinder

spacers of NC_015970_3

>3.1|50279|39|NC_015970|CRT
GGTGATCGGGCGTATCCGGGACAAACTCCAGAGACACGG
>3.2|50356|38|NC_015970|CRT
GGAGAAAGTAATCCGGGGCTGGCTGGCCGACGGATATC
>3.3|50432|40|NC_015970|CRT
GAATACGGCGGAAGCAAACTGGTTAACGGTGCGGTCGTCT
>3.4|50510|34|NC_015970|CRT
AAACGGAGATGCCATGCGGTCGCTCCGTGAAATC
>3.5|50582|40|NC_015970|CRT
TGCTATGAACAGCGCGATTTATCAGCCGTTTTTGAATGAG
>3.6|50660|36|NC_015970|CRT
GATGGATCGGCCGATCGCCTTTCACCGGGCATTCGC
>3.7|50734|36|NC_015970|CRT
GTTGTTTAAGGATGGTTTCTTTTACAATGCGCTTGA
>3.8|50279|40|NC_015970|PILER-CR,CRISPRCasFinder
GGTGATCGGGCGTATCCGGGACAAACTCCAGAGACACGGG
>3.9|50356|39|NC_015970|PILER-CR,CRISPRCasFinder
GGAGAAAGTAATCCGGGGCTGGCTGGCCGACGGATATCG
>3.10|50432|41|NC_015970|PILER-CR,CRISPRCasFinder
GAATACGGCGGAAGCAAACTGGTTAACGGTGCGGTCGTCTG
>3.11|50510|35|NC_015970|PILER-CR,CRISPRCasFinder
AAACGGAGATGCCATGCGGTCGCTCCGTGAAATCG
>3.12|50582|41|NC_015970|PILER-CR,CRISPRCasFinder
TGCTATGAACAGCGCGATTTATCAGCCGTTTTTGAATGAGA
>3.13|50660|37|NC_015970|PILER-CR,CRISPRCasFinder
GATGGATCGGCCGATCGCCTTTCACCGGGCATTCGCG
>3.14|50734|37|NC_015970|PILER-CR,CRISPRCasFinder
GTTGTTTAAGGATGGTTTCTTTTACAATGCGCTTGAG

CRISPR arrays and Neighbor proteins around NC_015970_3

CRISPR arrays

The CRISPR arrays of NC_015970_3

>merge|NC_015970|3|50241-50807|CRT,PILER-CR,CRISPRCasFinder
CGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGTGATCGGGCGTATCCGGGACAAACTCCAGAGACACGGGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGAGAAAGTAATCCGGGGCTGGCTGGCCGACGGATATCGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGAATACGGCGGAAGCAAACTGGTTAACGGTGCGGTCGTCTGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACAAACGGAGATGCCATGCGGTCGCTCCGTGAAATCGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTGCTATGAACAGCGCGATTTATCAGCCGTTTTTGAATGAGAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGATGGATCGGCCGATCGCCTTTCACCGGGCATTCGCGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGTTGTTTAAGGATGGTTTCTTTTACAATGCGCTTGAGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|3|2|50241-50807|CRT
CGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGTGATCGGGCGTATCCGGGACAAACTCCAGAGACACGG
GGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGAGAAAGTAATCCGGGGCTGGCTGGCCGACGGATATC
GGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GAATACGGCGGAAGCAAACTGGTTAACGGTGCGGTCGTCT
GGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AAACGGAGATGCCATGCGGTCGCTCCGTGAAATC
GGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGCTATGAACAGCGCGATTTATCAGCCGTTTTTGAATGAG
AGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GATGGATCGGCCGATCGCCTTTCACCGGGCATTCGC
GGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTTGTTTAAGGATGGTTTCTTTTACAATGCGCTTGA
GGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|3|2|50242-50807|PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGTGATCGGGCGTATCCGGGACAAACTCCAGAGACACGGG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGAGAAAGTAATCCGGGGCTGGCTGGCCGACGGATATCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GAATACGGCGGAAGCAAACTGGTTAACGGTGCGGTCGTCTG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AAACGGAGATGCCATGCGGTCGCTCCGTGAAATCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGCTATGAACAGCGCGATTTATCAGCCGTTTTTGAATGAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GATGGATCGGCCGATCGCCTTTCACCGGGCATTCGCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTTGTTTAAGGATGGTTTCTTTTACAATGCGCTTGAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|3|3|50242-50807|CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGTGATCGGGCGTATCCGGGACAAACTCCAGAGACACGGG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGAGAAAGTAATCCGGGGCTGGCTGGCCGACGGATATCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GAATACGGCGGAAGCAAACTGGTTAACGGTGCGGTCGTCTG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AAACGGAGATGCCATGCGGTCGCTCCGTGAAATCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGCTATGAACAGCGCGATTTATCAGCCGTTTTTGAATGAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GATGGATCGGCCGATCGCCTTTCACCGGGCATTCGCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTTGTTTAAGGATGGTTTCTTTTACAATGCGCTTGAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072530.1|41244_41751_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl|CDD|223747
NC_015970.1|WP_014072532.1|42290_43160_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072543.1|62720_63539_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	cas10	cd09680_cas10_CAS-III	gnl|CDD|274209
NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein	unknown	unknown	gnl|CDD|227209
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	gnl|CDD|187794
NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein	unknown	unknown	gnl|CDD|372298
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl|CDD|187793
NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein	unknown	unknown	gnl|CDD|370692
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl|CDD|367635
NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein	unknown	unknown	gnl|CDD|379423
NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224586
NC_015970.1|WP_027614258.1|38760_39030_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	csx1	cd09741_csx1_CAS-III	gnl|CDD|187872
NC_015970.1|WP_081472095.1|43246_43588_+|transposase	unknown	unknown	gnl|CDD|379129
NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein	unknown	unknown	gnl|CDD|223786
NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein	unknown	unknown	gnl|CDD|226382
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_015970.1|WP_014072531.1|41763_42294_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	1.3e-68	226.6	12.3
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	cas10	cd09680_cas10_CAS-III	7.8e-88	290.3	0.0
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	csx1	cd09741_csx1_CAS-III	2.9e-32	106.7	0.0
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	2.6e-44	146.5	0.0
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	4.4e-34	113.0	0.0
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	1.8e-26	87.6	0.0
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	4.4e-73	240.3	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.35007e-21
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	1.91901e-64
NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein	gnl|CDD|227209	COG4872, COG4872, Predicted membrane protein [Function unknown].	0.00993409
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|187794	cd09663, Csm4_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	2.9537e-29
NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein	gnl|CDD|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	1.87311e-10
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.2545e-28
NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein	gnl|CDD|370692	pfam09787, Golgin_A5, Golgin subfamily A member 5. Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.	1.09581e-05
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	9.83611e-36
NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein	gnl|CDD|379423	pfam14020, DUF4236, Protein of unknown function (DUF4236). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 69 and 402 amino acids in length.	1.49154e-06
NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein	gnl|CDD|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	7.40216e-22
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	gnl|CDD|187872	cd09741, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	8.67464e-26
NC_015970.1|WP_081472095.1|43246_43588_+|transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.00172e-05
NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	0.000569667
NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein	gnl|CDD|226382	COG3864, COG3864, Uncharacterized protein conserved in bacteria [Function unknown].	5.77271e-22
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.59974e-87

Protein sequences

>NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein
MKTLTFADWDTVFAYLGHLARQERLLVILDEFPYLCEAAPELPSIIQRFWDLEEQHSRLFLVRCGSQPGFMEREVLGERSPLYGRRTGQLRLQPLDYREAGQFFAGYGWRDRLLAYGMLGGMPAYLQRFEPKRSLRENLLQEMLSAQGYLYEEPRFLLRMELRDVRVYASILGAIASGCTRLNEIAQRVGVAAHAVSKYLSVLQELGLIARAVPFLARAPQRSKQGRYHMLDPFLRCWYRFVYPHATLIEARQGELVYERFIRPQLDPYMGGIFEEVARAYMERYAAAELGVPPVVRTGREWAGDFDLDLMAEHADGSWTIGECKWTRRPVGVEVLRELRSRWERLGRRQRLPERVRYFIFSSGGFTPGLLRQRDGAIRLLGLAELFGEVSTTAEG
>NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MLRAYRLELEIASERKRRFLHQHFGAARFIYNWALRLVREKGFEFFKQGKGGIGKRILYYWREERDKVAPWHHEINAHTFNGAVLDLGRDLKHHSPSQLRGRSRNRHRSAHFYGIKLQHIGRRSIKLPGSRAGEFRGGVYLKVKKGTGKLYEDIQQGRIRTIKRITVSERAGRYFASVLCEVQEPEPLPCTGRVCGLDVGISSIVTVALSDGRIIKQGNPQWLAKKLRRLRRIQRSLARCKTHFPRDPGFKSLHILRRDGEVLAVFPLMWRRQNGELVPEVGDDVRILAEGVASYALLSRAPDRLEKPYRLTVGGQGSGANIELSTMRIRQGHPVRVVHLSVDRSHTMERRRKTLARAHYRVSVAREDFWHRLSTWLVRNCDVIVVESLSIKGMLRSGRFSRHIADAAWGTFFQMLQYKCERYGRTLLRVERSYPSSKKCSRCGKIRKALSLSERTYRCDQCGLKIDRDENAALNLMKLGLAHLTSPTARLAGSDAGGGTIAGGAAACT
>NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein
MGGGSHQWASEAADAAADKETLQDFVHRFTRAEAWVSPDAWRGYAALARAHEVVRHGQGEWARDGRREVHVNTTEGMWTEVRDFLRPFKGVHKRYLPGYLAMAEFCRNLKRITPAFIAALVRLPCAHFL
>NC_015970.1|WP_081472095.1|43246_43588_+|transposase
MTHNGHASSPDRRGRPRRADREILEAIVWILHTGAPGAKLPAQVHLPRSLPSVEPKRHPPTNCWPKNATNRASSNFRRAWLIYKKCAQGRRTRAAMKAGVMRFRLRQNSAIAR
>NC_015970.1|WP_014072532.1|42290_43160_+|hypothetical-protein
MTPLLRPTRRWKFTPDRQQRRLLRDLADQTGTHGIALALVAVPQDAPLSAERYLEVLSNESARQRYREILRRKHRPRCLAYSIHLGPDVSYDAAALHHKHVCWRVFKTGDGPELREAQRYQELEQRLVHELLKVPTYGELAQVVRGAFRRSFERSDQVFRERGFQLLDRVPETLEPVLEGYRYRVLSRFVDVLDHIQDDQLLRMRSPSLGAPGTQERIHAVMQRYRSAVLLHVEHRGFALVAVSGRVAWSLSYPDASIAPLTRCFGVHYKQFARVLEDMTGMHEVDFPF
>NC_015970.1|WP_014072531.1|41763_42294_+|hypothetical-protein
MKLRIAGVGHVPLSGQVSRELLQLAVRAPRAVRWLLETQRHMEGRLRRADALPFLERVLALPARDLAYFMTGVHPSMVLCLLHAVLERESCYRVFRSMPRPVLRRYFPVLYNPGDVDAADAVLARRGKPHRWRIVYNTEPLVKAARSTEVQPLYALLMEYPESRVFVFNSQSVELS
>NC_015970.1|WP_014072530.1|41244_41751_+|hypothetical-protein
MKLHVAGMGYVPVPEKLQRKLLRAAVRTPRVASWLYTVQSGLGLSRAQIEELLERAAELPVGTLRTVLARAGALGIDLLRRMLDDRKRLHVISQLPPSVYLRVHGLAFDTLEKVLHRYGRPRRWVVEQSPDRAVDGRALRNPCGPHGRGHGLCGPVRAAHRSGIGVRH
>NC_015970.1|WP_014072529.1|39967_41248_+|hypothetical-protein
MSIVKARLTKEQALEIRRTLLHLHARMPFWAALVRHTSVVASRAVPTAAVTPADVVLVNPEYFFGLTTGQRIFLLAHEAAHLALRVFERLGARNRLVWNVAQDLLINELVLTDFKQRFKTGDVPPGALLLRQSVSELTSDQLYEMIMHLADEAGLELEGARHASAGRRLCAQHPDIARELRERILPFLERYTSDLLEEAPEDGKVLIEGEQDGGSWEFRVRRALAHSRLHGTQARGAEIFARVATRPRVHWRLPLAAAIRQLAARELKLDYTFMHPNHRRMQGGEVVLPTMTGARGRAVFAVDTSGSMLTLMPDGEHSYLEQALAELDSARRQFQLEVYLINCDANVYVSGWIQPYEPLPEPKGGGGTSFVPVFQHIEERKLRPNFVVVLTDGEGTYPETPPPYDVIWVVFGDRTPPFGQVIRVEL
>NC_015970.1|WP_027912201.1|39131_39971_+|hypothetical-protein
MASEPDEESQVVWSRPDFWPREGKGIIVFEELNTAPPSVQNTLLQPFGAPPGADRYVGPHRIPRTFYLCATGNRREDHAHVVALSSALRGRAVIINIPGPNLESWTTWAAEHGVEPAVVAFIRFRPDLLYQPPPAHDETAPFPSPRAWARFVSPLVARGFTTPEMLAAAVGEEAASEFLAFLQEIDSMPDVDRLLARPDELNPEALSLSVRYAIVSALIHRVVSNPKLLAQAAAVAVHFEPELAAVFLSTLIRLGFQTQIFGLRVAHDWVKQHGKLLKI
>NC_015970.1|WP_027614258.1|38760_39030_-|hypothetical-protein
MTHDGHAAHVHRIELPGPQIDQDVVLLQRRLNSFGLADARRTQDEGGNAKGAKLPDDVGKTPDVHNVELLHGFTWDRGSDEKGMLSREI
>NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MPVTLKLITRSPLHIGSGHELESFEYIIHDGFFWRLDINRVTAFLLDEIGEEALEQFSSWIEWKTDRLADARNNREQAEIRRSLTLRTFVRGELGRPDLDARLLQQLQSRSRYAMRTSFSEFRQLVREQLKDPDGRLYIPGSSLKGALRTCLLYQVLVEADEKTHRRWLAELRDSLGRAGRSLNRRERVFFSRWLEEDVFYCGVRKKGKVSWRDAQFDLLKFLRISDSSSVAADEIGVVTDVEIFLPGAEPQPQAPPVEALEAGAELQAQVGFDVSFFREAHRLLARGEKGMGTDIWIGLPEKFQRLYGLTLEEAAAMEAEELERRLLERVRKAARNFGRALKAFEKEWCRRAERGSTLQQARRLQRFYDELPDDCLRLGWGSGFAAVTVYLALREKPAWKEPLQNLLHRLFSLKEREDLLQTFPTSRRMAIDGEGTMVEEPMGWVELEWPWSATEAAATTEEEAAEDESDLWVDQIGPNSQDIIAEVVDNSRAPFTIRIFVRGLENERFPCGGASHRAIEVGQRIRVKVSQWNKKAGRPTMFSVQSIRV
>NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MTFQAVYLYPRSSFRTPLRSDTLWGLLVVALRVVAGDREADAFIEACEQGRPPIRLASAFPFVQEQSADGRPVFRHFFPRPVLPPPLLEPSQADARVVFEQMKQGKKVRRIRWLPQELFERVLRGELDEAGLQQELLQQEQSGARKRWPVLLTQDNLHTSIDRLTGTTRQENGAGQLFYSHEYYMKRGQGLFFLVEGEVARILPALRYLHHVGWGGDSSVGKGHFDWELRELELRVPEKPTHRLLLSLYSPTRAELDHIRQHRDRTFYQLERRQGYAGAHRLPGRAYLKRPLYMLSEGSLVPDPGRPLLGAVHTVMEADGVRVRHSGLALDLPARVGLS
>NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MAGFLGNIILKGKMECLTGLHIGGSKEKFEIGGVDQPVIRDPATNYPYVPGSSLKGKMRALLSFALGKAHEDPNFRSFDPNCPLQRVFGTSAESRNIGPSRLVVRDAFPDEATIRMWENLDTELLYTEIKAENSVDRLTSAANPRFPERVVRGSRFNVEFVFSVYESQDADYFRYVIEGLRLLEHSWLGRSGTRGYGQVKFKLTEPIIVTLDDYLEGTEAYRKASRSHEEMTFDLETADFNESRFNQIKQQFLQIAEKLATNQA
>NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2
MNIPGDLAKLKPEEIDSLANEMGRKYAQNVKTAQVRNVFAHINRMRTRMRRGQGIGPEMRRDLVMLKPRLAYAGGRQREVRPMSDDLRQAVDAVLNSENFEQALRNFFDLVEGIVAYHKYHGGKEN
>NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1
MDRSQIEYLGGLLHAIGLLEQLGREQFDAPGISSLQFTEQLLQHCPAFAPHAEAIREAVRQAADALPAEPPPSWLEPLLQRVRLPGHPEPTGGRVFPPRSLSDGVVYPVAPEAVGDGREACRKLWQDLQAEAVRTLQGIEDVGAALETLYTLLEKYTSYIPAPAVQARGVSLFDYSRVTAALRLCRTRAEREPAVLLVKGDVSGIQSFIYRELRGDETENPAQLLRGRSFFVALLARTVVRHLQRLFQLPDGCVLYSSGGHFVMLLPNTEDARQRLDEADRSINQALFRELNGAIQLVLAHAEADARTIEHDPSEALYRLEETLQIAKLRKGWSVLETLVGQPIGETPALPKLNPVGQALPYTDYLIEVPELPASEVPEGTRTELALSGFETTWLFVEEEALEPVLRRLGARSATVFNLRTTKIPAVAVARRTGYRLMPAGVYVPMTEASESRRPLMFEELAAIESANYPLLGFLRMDVDNLGALFVVGLREAFGEHRFGLHRTAALSRELDRFFGAHVNTLARGLDVYLVYAGGDDLFAVGSWVRVLRFARSIREKLREYCGDNPSVTISAGLSIHKEHFPITVAADAAGEEEERAKQAGKNRISLFETPVAWEQLRHLVDELAEPLLQAIIDETLPEEERVPRTFVHTLLRYSREVLDEDGRVDLGALARLNHLLHYTFARRNVREEMLQQAPDRPLVRLVQGFLLLERPDRSEWFRTFVIPAAYVLLKTRKQRD
>NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase
MATLGEQPQVVTLTLDLLAARRVTFDELVLFHTEPHYPALQRALQRLETELAQWPAYRELTVRRVLFRDEAGRPLTDVRADAEARQVYRILFREVLEVKRQRRPLHFLIAGGRKVMAAYGMAVVQLLGEAGDQVWHLISEGELLASGRMHPEPGDRVHLVPVPFLRWSALPPAATRLAVTGDPFEAMRLHEAWLDEESRRQRAWFLLHELTPAERTLLVALARTGASNSELARMLKRSPKTVANQLATVADKYRAFAGLADEVPLSRAELVAHFAPVLDRIEDPCGIDTL
>NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein
MPLHLYKTFRLGPVRLTISHRGIGLSVGTRGLRIGRTPSGRPYIRLGRGHWRLEKRGR
>NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein
MPQPAPEAFGEPSPPAPPEVPDWIADDGLLRDEGVIVGRALSTDPPAPNDGPHHWKLETIRAYYDERRAPLRAQLEAAHRQLERLQRREAVLREDLERHERALAALAEVEPRLPLTGRNLVLSVMLTVVCALTPLVLAELLPPDRFDHPMAVALALSLFGLFAVFQGRSLLVAADARLSGAPARPERWKLYAMEVLPPLAVALLIAVFVHRPEQGWFPTLAIGFAVLLLLLIPGRLLMSLLARTLPELSGWWRMFVHRRRLRRHHRQAAAALRRELEALAGLRAQLEDETIPQIQRKLAFLDARCRRKEALFRSEMELARRRNLLRARHESNGQMHTVSS
>NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein
MLAILRRKLRAEAPDTPRFTLPLPVGTEEPDPNSPHLYGQYDGGLAIDNDAFAEFLQAATRREHLSERIATLQKQREQLQEQLQRAEAAQISAQTLPERLQALERALPEARQRLEQVRRQREQCEQELQALRRSPEVPSLVQVLMYGAAGVAFLVGDIIVSKEIVAQVLYLPLEYERWLFALGLACITFVLKVAYDRLVELPFWQHIRRRFEVVILSISALALITLVFMGALRTQEIQRQHLLRSTEQTVWSLEAESPSVQQQIPTPDNTVLLVTFILSAVMFATAGAVCFSTAHTHARGYFHVYRPLREAYDALTVQEQNATRRLETLEESLTADREELARANATLALVGTPEMLRQDLKQIDEHIAGLQEQLADLLSEQRRASYRSGRERALQYRRLLTEKPAEDEVAEAPEESPAEDETGESMAASGEISSDADQEAIPLGSEENGTTLPETAHPMAIDGAPDGTADLPEGITDPDEAGAGHSAEPDEAGAESTAVVIGNIETATASTTEGADATEGASATEAASTFEGGDNESDGLAGTPDALSLEAGDAVVGDESAAAGGDSSVRAATPRSRRERGVRHGLRRPFLDIRDEILDLTA
>NC_015970.1|WP_014072543.1|62720_63539_+|hypothetical-protein
MRRFWFYCLIFILGCSSEAQRDPLTACADESLAHESLTGIPRTALVFIDRSSSATASPDTRRAFETALRQQVESILPIRGGTIHVFFVHSRTTGKADARTFVQDAPLPRVSPYDSEQRQACRQYITEVRRRMQAAFDSLRQTLDARMTASVTEATDLWGIFEVISETLPASSQMPPATVLVLSDLLECMPGPERRCFESRPPTSRAQAEAWAREDAERILRSYRIRPEVLRQAHYLLISGDFANREQSRYVRYYWFALLEAFGVPYEQISIQ

Crispr_ID: NC_015970_4

• CRISPR_ID: NC_015970_4
• CRISPR_location: 58250-59274
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 13 spacers
• Cas_protein_info: csx1,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,c2c9_V-U4,csx20

Consensus repeat of NC_015970_4

Consensus_repeat	Method
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	PILER-CR

spacers of NC_015970_4

>4.1|58287|40|NC_015970|CRISPRCasFinder,CRT
TGGCACCCAGATCGTCCCGAGCCCGGTCAATATGCACGGT
>4.2|58364|36|NC_015970|CRISPRCasFinder,CRT,PILER-CR
TTGAAAAGCTTGTGCTCAACGAACAGGCGCGTATGC
>4.3|58437|41|NC_015970|CRISPRCasFinder,CRT,PILER-CR
AGGATCCTCAGGGGCAGCAGCGCATTCCGGACTGGGAGGCC
>4.4|58515|39|NC_015970|CRISPRCasFinder,CRT,PILER-CR
GATGAGCCAGACGAGGGGTGGGTAAATAAGTACTATGAC
>4.5|58591|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR
CATCGACGGGCGTGAGATGGACGAGGATGCGCTCTACGAG
>4.6|58668|36|NC_015970|CRISPRCasFinder,CRT,PILER-CR
CTGGACTGGTGCCAGCGCTACCTCGGCGAAGAGGCC
>4.7|58741|34|NC_015970|CRISPRCasFinder,CRT,PILER-CR
CGACGATCGCACGCTGCTTATGGCGCTCATTCCC
>4.8|58812|39|NC_015970|CRISPRCasFinder,CRT,PILER-CR
TCATCGAAGAGATGATGGACGTGCTCGAAAAGCTTGAGC
>4.9|58888|41|NC_015970|CRISPRCasFinder,CRT,PILER-CR
GCAAGCGCTCAGCAGGCATTGTCGTTGAGCTGTAGCCAGCA
>4.10|58966|43|NC_015970|CRISPRCasFinder,CRT,PILER-CR
CGACTTGAAAGAAAGGTTCGACGTGCTCCCGTACGAGATCCCA
>4.11|59046|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR
TCAAGGATGAGGTGCTGGGATGGACCAACAGAGCCAACAG
>4.12|59123|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR
GCGACGTGGTGAGTCCCGACACCGGCCCGGAGAGTGCTAT
>4.13|59200|38|NC_015970|CRISPRCasFinder,CRT,PILER-CR
GGATCAATGAGCTTGGTTTCCAGGAGACTCCCAGCGGC

CRISPR arrays and Neighbor proteins around NC_015970_4

CRISPR arrays

The CRISPR arrays of NC_015970_4

>merge|NC_015970|4|58250-59274|CRISPRCasFinder,CRT,PILER-CR
ATTGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTGGCACCCAGATCGTCCCGAGCCCGGTCAATATGCACGGTGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTTGAAAAGCTTGTGCTCAACGAACAGGCGCGTATGCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACAGGATCCTCAGGGGCAGCAGCGCATTCCGGACTGGGAGGCCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGATGAGCCAGACGAGGGGTGGGTAAATAAGTACTATGACGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCATCGACGGGCGTGAGATGGACGAGGATGCGCTCTACGAGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCTGGACTGGTGCCAGCGCTACCTCGGCGAAGAGGCCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCGACGATCGCACGCTGCTTATGGCGCTCATTCCCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTCATCGAAGAGATGATGGACGTGCTCGAAAAGCTTGAGCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGCAAGCGCTCAGCAGGCATTGTCGTTGAGCTGTAGCCAGCAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCGACTTGAAAGAAAGGTTCGACGTGCTCCCGTACGAGATCCCAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTCAAGGATGAGGTGCTGGGATGGACCAACAGAGCCAACAGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGCGACGTGGTGAGTCCCGACACCGGCCCGGAGAGTGCTATGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGATCAATGAGCTTGGTTTCCAGGAGACTCCCAGCGGCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|4|4|58250-59274|CRISPRCasFinder
ATTGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGCACCCAGATCGTCCCGAGCCCGGTCAATATGCACGGT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TTGAAAAGCTTGTGCTCAACGAACAGGCGCGTATGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AGGATCCTCAGGGGCAGCAGCGCATTCCGGACTGGGAGGCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GATGAGCCAGACGAGGGGTGGGTAAATAAGTACTATGAC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CATCGACGGGCGTGAGATGGACGAGGATGCGCTCTACGAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CTGGACTGGTGCCAGCGCTACCTCGGCGAAGAGGCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGACGATCGCACGCTGCTTATGGCGCTCATTCCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TCATCGAAGAGATGATGGACGTGCTCGAAAAGCTTGAGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GCAAGCGCTCAGCAGGCATTGTCGTTGAGCTGTAGCCAGCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGACTTGAAAGAAAGGTTCGACGTGCTCCCGTACGAGATCCCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TCAAGGATGAGGTGCTGGGATGGACCAACAGAGCCAACAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GCGACGTGGTGAGTCCCGACACCGGCCCGGAGAGTGCTAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGATCAATGAGCTTGGTTTCCAGGAGACTCCCAGCGGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|4|3|58250-59274|CRT
ATTGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGCACCCAGATCGTCCCGAGCCCGGTCAATATGCACGGT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TTGAAAAGCTTGTGCTCAACGAACAGGCGCGTATGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AGGATCCTCAGGGGCAGCAGCGCATTCCGGACTGGGAGGCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GATGAGCCAGACGAGGGGTGGGTAAATAAGTACTATGAC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CATCGACGGGCGTGAGATGGACGAGGATGCGCTCTACGAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CTGGACTGGTGCCAGCGCTACCTCGGCGAAGAGGCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGACGATCGCACGCTGCTTATGGCGCTCATTCCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TCATCGAAGAGATGATGGACGTGCTCGAAAAGCTTGAGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GCAAGCGCTCAGCAGGCATTGTCGTTGAGCTGTAGCCAGCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGACTTGAAAGAAAGGTTCGACGTGCTCCCGTACGAGATCCCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TCAAGGATGAGGTGCTGGGATGGACCAACAGAGCCAACAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GCGACGTGGTGAGTCCCGACACCGGCCCGGAGAGTGCTAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGATCAATGAGCTTGGTTTCCAGGAGACTCCCAGCGGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|4|3|58327-59274|PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TTGAAAAGCTTGTGCTCAACGAACAGGCGCGTATGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AGGATCCTCAGGGGCAGCAGCGCATTCCGGACTGGGAGGCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GATGAGCCAGACGAGGGGTGGGTAAATAAGTACTATGAC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CATCGACGGGCGTGAGATGGACGAGGATGCGCTCTACGAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CTGGACTGGTGCCAGCGCTACCTCGGCGAAGAGGCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGACGATCGCACGCTGCTTATGGCGCTCATTCCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TCATCGAAGAGATGATGGACGTGCTCGAAAAGCTTGAGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GCAAGCGCTCAGCAGGCATTGTCGTTGAGCTGTAGCCAGCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGACTTGAAAGAAAGGTTCGACGTGCTCCCGTACGAGATCCCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TCAAGGATGAGGTGCTGGGATGGACCAACAGAGCCAACAG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GCGACGTGGTGAGTCCCGACACCGGCCCGGAGAGTGCTAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGATCAATGAGCTTGGTTTCCAGGAGACTCCCAGCGGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl|CDD|187817
NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein	unknown	unknown	gnl|CDD|379423
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	cas10	cd09680_cas10_CAS-III	gnl|CDD|274209
NC_015970.1|WP_014072544.1|65309_65708_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein	unknown	unknown	gnl|CDD|227209
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	gnl|CDD|187794
NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein	unknown	unknown	gnl|CDD|372298
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl|CDD|187793
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl|CDD|223747
NC_015970.1|WP_012845312.1|65711_66077_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl|CDD|367635
NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224586
NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|187863
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	csx1	cd09741_csx1_CAS-III	gnl|CDD|187872
NC_015970.1|WP_012845310.1|64803_65196_+|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	unknown
NC_015970.1|WP_081472095.1|43246_43588_+|transposase	unknown	unknown	gnl|CDD|379129
NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein	unknown	unknown	gnl|CDD|370692
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815
NC_015970.1|WP_014072543.1|62720_63539_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	3.4e-70	231.7	0.0
NC_015970.1|WP_012845310.1|64803_65196_+|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	3.8e-73	238.6	0.0
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	1.3e-68	226.6	12.3
NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	3.6e-50	165.9	0.0
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	cas10	cd09680_cas10_CAS-III	7.8e-88	290.3	0.0
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	csx1	cd09741_csx1_CAS-III	2.9e-32	106.7	0.0
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	2.6e-44	146.5	0.0
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	4.4e-34	113.0	0.0
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	1.8e-26	87.6	0.0
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	4.4e-73	240.3	0.0
NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	9.6e-44	144.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein	gnl|CDD|379423	pfam14020, DUF4236, Protein of unknown function (DUF4236). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 69 and 402 amino acids in length.	1.49154e-06
NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1	gnl|CDD|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	1.91901e-64
NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein	gnl|CDD|227209	COG4872, COG4872, Predicted membrane protein [Function unknown].	0.00993409
NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|187794	cd09663, Csm4_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	2.9537e-29
NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein	gnl|CDD|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	1.87311e-10
NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.2545e-28
NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.35007e-21
NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	9.83611e-36
NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	5.09194e-80
NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein	gnl|CDD|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	7.40216e-22
NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase	gnl|CDD|187872	cd09741, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	8.67464e-26
NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein	gnl|CDD|187817	cd09686, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	9.00068e-41
NC_015970.1|WP_081472095.1|43246_43588_+|transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.00172e-05
NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein	gnl|CDD|370692	pfam09787, Golgin_A5, Golgin subfamily A member 5. Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.	1.09581e-05
NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.59974e-87
NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	1.1845e-40

Protein sequences

>NC_015970.1|WP_155816014.1|57218_58091_-|histidine-kinase
MATLGEQPQVVTLTLDLLAARRVTFDELVLFHTEPHYPALQRALQRLETELAQWPAYRELTVRRVLFRDEAGRPLTDVRADAEARQVYRILFREVLEVKRQRRPLHFLIAGGRKVMAAYGMAVVQLLGEAGDQVWHLISEGELLASGRMHPEPGDRVHLVPVPFLRWSALPPAATRLAVTGDPFEAMRLHEAWLDEESRRQRAWFLLHELTPAERTLLVALARTGASNSELARMLKRSPKTVANQLATVADKYRAFAGLADEVPLSRAELVAHFAPVLDRIEDPCGIDTL
>NC_015970.1|WP_014072539.1|54901_57115_-|CRISPR-associated-protein-Csm1
MDRSQIEYLGGLLHAIGLLEQLGREQFDAPGISSLQFTEQLLQHCPAFAPHAEAIREAVRQAADALPAEPPPSWLEPLLQRVRLPGHPEPTGGRVFPPRSLSDGVVYPVAPEAVGDGREACRKLWQDLQAEAVRTLQGIEDVGAALETLYTLLEKYTSYIPAPAVQARGVSLFDYSRVTAALRLCRTRAEREPAVLLVKGDVSGIQSFIYRELRGDETENPAQLLRGRSFFVALLARTVVRHLQRLFQLPDGCVLYSSGGHFVMLLPNTEDARQRLDEADRSINQALFRELNGAIQLVLAHAEADARTIEHDPSEALYRLEETLQIAKLRKGWSVLETLVGQPIGETPALPKLNPVGQALPYTDYLIEVPELPASEVPEGTRTELALSGFETTWLFVEEEALEPVLRRLGARSATVFNLRTTKIPAVAVARRTGYRLMPAGVYVPMTEASESRRPLMFEELAAIESANYPLLGFLRMDVDNLGALFVVGLREAFGEHRFGLHRTAALSRELDRFFGAHVNTLARGLDVYLVYAGGDDLFAVGSWVRVLRFARSIREKLREYCGDNPSVTISAGLSIHKEHFPITVAADAAGEEEERAKQAGKNRISLFETPVAWEQLRHLVDELAEPLLQAIIDETLPEEERVPRTFVHTLLRYSREVLDEDGRVDLGALARLNHLLHYTFARRNVREEMLQQAPDRPLVRLVQGFLLLERPDRSEWFRTFVIPAAYVLLKTRKQRD
>NC_015970.1|WP_014072538.1|54491_54872_-|type-III-A-CRISPR-associated-protein-Csm2
MNIPGDLAKLKPEEIDSLANEMGRKYAQNVKTAQVRNVFAHINRMRTRMRRGQGIGPEMRRDLVMLKPRLAYAGGRQREVRPMSDDLRQAVDAVLNSENFEQALRNFFDLVEGIVAYHKYHGGKEN
>NC_015970.1|WP_014072537.1|53680_54475_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MAGFLGNIILKGKMECLTGLHIGGSKEKFEIGGVDQPVIRDPATNYPYVPGSSLKGKMRALLSFALGKAHEDPNFRSFDPNCPLQRVFGTSAESRNIGPSRLVVRDAFPDEATIRMWENLDTELLYTEIKAENSVDRLTSAANPRFPERVVRGSRFNVEFVFSVYESQDADYFRYVIEGLRLLEHSWLGRSGTRGYGQVKFKLTEPIIVTLDDYLEGTEAYRKASRSHEEMTFDLETADFNESRFNQIKQQFLQIAEKLATNQA
>NC_015970.1|WP_014072536.1|52664_53684_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MTFQAVYLYPRSSFRTPLRSDTLWGLLVVALRVVAGDREADAFIEACEQGRPPIRLASAFPFVQEQSADGRPVFRHFFPRPVLPPPLLEPSQADARVVFEQMKQGKKVRRIRWLPQELFERVLRGELDEAGLQQELLQQEQSGARKRWPVLLTQDNLHTSIDRLTGTTRQENGAGQLFYSHEYYMKRGQGLFFLVEGEVARILPALRYLHHVGWGGDSSVGKGHFDWELRELELRVPEKPTHRLLLSLYSPTRAELDHIRQHRDRTFYQLERRQGYAGAHRLPGRAYLKRPLYMLSEGSLVPDPGRPLLGAVHTVMEADGVRVRHSGLALDLPARVGLS
>NC_015970.1|WP_014072535.1|50993_52646_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MPVTLKLITRSPLHIGSGHELESFEYIIHDGFFWRLDINRVTAFLLDEIGEEALEQFSSWIEWKTDRLADARNNREQAEIRRSLTLRTFVRGELGRPDLDARLLQQLQSRSRYAMRTSFSEFRQLVREQLKDPDGRLYIPGSSLKGALRTCLLYQVLVEADEKTHRRWLAELRDSLGRAGRSLNRRERVFFSRWLEEDVFYCGVRKKGKVSWRDAQFDLLKFLRISDSSSVAADEIGVVTDVEIFLPGAEPQPQAPPVEALEAGAELQAQVGFDVSFFREAHRLLARGEKGMGTDIWIGLPEKFQRLYGLTLEEAAAMEAEELERRLLERVRKAARNFGRALKAFEKEWCRRAERGSTLQQARRLQRFYDELPDDCLRLGWGSGFAAVTVYLALREKPAWKEPLQNLLHRLFSLKEREDLLQTFPTSRRMAIDGEGTMVEEPMGWVELEWPWSATEAAATTEEEAAEDESDLWVDQIGPNSQDIIAEVVDNSRAPFTIRIFVRGLENERFPCGGASHRAIEVGQRIRVKVSQWNKKAGRPTMFSVQSIRV
>NC_015970.1|WP_027614255.1|48256_49447_-|ATP-binding-protein
MKTLTFADWDTVFAYLGHLARQERLLVILDEFPYLCEAAPELPSIIQRFWDLEEQHSRLFLVRCGSQPGFMEREVLGERSPLYGRRTGQLRLQPLDYREAGQFFAGYGWRDRLLAYGMLGGMPAYLQRFEPKRSLRENLLQEMLSAQGYLYEEPRFLLRMELRDVRVYASILGAIASGCTRLNEIAQRVGVAAHAVSKYLSVLQELGLIARAVPFLARAPQRSKQGRYHMLDPFLRCWYRFVYPHATLIEARQGELVYERFIRPQLDPYMGGIFEEVARAYMERYAAAELGVPPVVRTGREWAGDFDLDLMAEHADGSWTIGECKWTRRPVGVEVLRELRSRWERLGRRQRLPERVRYFIFSSGGFTPGLLRQRDGAIRLLGLAELFGEVSTTAEG
>NC_015970.1|WP_014072533.1|44554_46084_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MLRAYRLELEIASERKRRFLHQHFGAARFIYNWALRLVREKGFEFFKQGKGGIGKRILYYWREERDKVAPWHHEINAHTFNGAVLDLGRDLKHHSPSQLRGRSRNRHRSAHFYGIKLQHIGRRSIKLPGSRAGEFRGGVYLKVKKGTGKLYEDIQQGRIRTIKRITVSERAGRYFASVLCEVQEPEPLPCTGRVCGLDVGISSIVTVALSDGRIIKQGNPQWLAKKLRRLRRIQRSLARCKTHFPRDPGFKSLHILRRDGEVLAVFPLMWRRQNGELVPEVGDDVRILAEGVASYALLSRAPDRLEKPYRLTVGGQGSGANIELSTMRIRQGHPVRVVHLSVDRSHTMERRRKTLARAHYRVSVAREDFWHRLSTWLVRNCDVIVVESLSIKGMLRSGRFSRHIADAAWGTFFQMLQYKCERYGRTLLRVERSYPSSKKCSRCGKIRKALSLSERTYRCDQCGLKIDRDENAALNLMKLGLAHLTSPTARLAGSDAGGGTIAGGAAACT
>NC_015970.1|WP_081472096.1|43491_43881_-|hypothetical-protein
MGGGSHQWASEAADAAADKETLQDFVHRFTRAEAWVSPDAWRGYAALARAHEVVRHGQGEWARDGRREVHVNTTEGMWTEVRDFLRPFKGVHKRYLPGYLAMAEFCRNLKRITPAFIAALVRLPCAHFL
>NC_015970.1|WP_081472095.1|43246_43588_+|transposase
MTHNGHASSPDRRGRPRRADREILEAIVWILHTGAPGAKLPAQVHLPRSLPSVEPKRHPPTNCWPKNATNRASSNFRRAWLIYKKCAQGRRTRAAMKAGVMRFRLRQNSAIAR
>NC_015970.1|WP_012845305.1|59562_59739_+|DUF4236-domain-containing-protein
MPLHLYKTFRLGPVRLTISHRGIGLSVGTRGLRIGRTPSGRPYIRLGRGHWRLEKRGR
>NC_015970.1|WP_155816015.1|59863_60886_+|hypothetical-protein
MPQPAPEAFGEPSPPAPPEVPDWIADDGLLRDEGVIVGRALSTDPPAPNDGPHHWKLETIRAYYDERRAPLRAQLEAAHRQLERLQRREAVLREDLERHERALAALAEVEPRLPLTGRNLVLSVMLTVVCALTPLVLAELLPPDRFDHPMAVALALSLFGLFAVFQGRSLLVAADARLSGAPARPERWKLYAMEVLPPLAVALLIAVFVHRPEQGWFPTLAIGFAVLLLLLIPGRLLMSLLARTLPELSGWWRMFVHRRRLRRHHRQAAAALRRELEALAGLRAQLEDETIPQIQRKLAFLDARCRRKEALFRSEMELARRRNLLRARHESNGQMHTVSS
>NC_015970.1|WP_014072542.1|60904_62713_+|hypothetical-protein
MLAILRRKLRAEAPDTPRFTLPLPVGTEEPDPNSPHLYGQYDGGLAIDNDAFAEFLQAATRREHLSERIATLQKQREQLQEQLQRAEAAQISAQTLPERLQALERALPEARQRLEQVRRQREQCEQELQALRRSPEVPSLVQVLMYGAAGVAFLVGDIIVSKEIVAQVLYLPLEYERWLFALGLACITFVLKVAYDRLVELPFWQHIRRRFEVVILSISALALITLVFMGALRTQEIQRQHLLRSTEQTVWSLEAESPSVQQQIPTPDNTVLLVTFILSAVMFATAGAVCFSTAHTHARGYFHVYRPLREAYDALTVQEQNATRRLETLEESLTADREELARANATLALVGTPEMLRQDLKQIDEHIAGLQEQLADLLSEQRRASYRSGRERALQYRRLLTEKPAEDEVAEAPEESPAEDETGESMAASGEISSDADQEAIPLGSEENGTTLPETAHPMAIDGAPDGTADLPEGITDPDEAGAGHSAEPDEAGAESTAVVIGNIETATASTTEGADATEGASATEAASTFEGGDNESDGLAGTPDALSLEAGDAVVGDESAAAGGDSSVRAATPRSRRERGVRHGLRRPFLDIRDEILDLTA
>NC_015970.1|WP_014072543.1|62720_63539_+|hypothetical-protein
MRRFWFYCLIFILGCSSEAQRDPLTACADESLAHESLTGIPRTALVFIDRSSSATASPDTRRAFETALRQQVESILPIRGGTIHVFFVHSRTTGKADARTFVQDAPLPRVSPYDSEQRQACRQYITEVRRRMQAAFDSLRQTLDARMTASVTEATDLWGIFEVISETLPASSQMPPATVLVLSDLLECMPGPERRCFESRPPTSRAQAEAWAREDAERILRSYRIRPEVLRQAHYLLISGDFANREQSRYVRYYWFALLEAFGVPYEQISIQ
>NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein
MERVLLSFIGTGNYQPCIYVWGDHRCKTPYFQEAAVRFFNPDQCLVLMTEMAQKKHGAALRRRIKRIVYQRSKKARAACNSKNALRKRIKRIVYRPVSIPDGRNEDELWAIFSALTDCIPEGATLIVDVTHGFRTQPMLALAALCYLRVARNVQIERIIYGAFEARHPDTSEAPVFDLTPFLTLIDWSVAAHQFIHYGQANDLARLIREIHRLTYVEQAQVQAQHAATAASWLEGFARALGLVRLAEVMTEHALRLPEALERMRQDVDQIARLRPFGLLLDITAERARSLHHPDPLSLDGLRLQAELIRHLLNYGLVQQAVTVAREAIVTRYALDLGRDPLQEREAVEHELGRLASGLQDPAVRAGYTPETHQLAELWNRLTNVRNDINHAGMRTNPETTNNLYRLASECAEAAANWIARDAHQPE
>NC_015970.1|WP_012845310.1|64803_65196_+|hypothetical-protein
MLINLSNHPASTWGKAQREASRMYGEVEDWPFPLIPPEWDAHQVAGLAQDYAERIVRRLNEAGGGRHAVHVMGEMTFTCTLVRLLHQRGILCLASTSQRIVEEDPASGKKIACFRFERFRPYPCLQALSF
>NC_015970.1|WP_014072544.1|65309_65708_+|hypothetical-protein
MRTTHNLILYITDMEPADLRTAERLIEAFEEELGCVLEYDPEHRMLSLHTAMVVEPAEASGAALRQMLHCIRHLAGRFLQEYRLIFSVSARSSASGSRPLGTVLERSPYDRLLSQLITPEYPRLLPPEPPLC
>NC_015970.1|WP_012845312.1|65711_66077_+|hypothetical-protein
MRVWLTNFFAREVPCTLEISVTLEGGEHPPQLVDFLRKRADRLWTNPDGSMLAIFIREFRLESLQERLPWFLRALELRLLRLGACHGTLAWRPAFAYDWSLEGRGCSRERALEQLLRLQRN
>NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein
MERYNLLIALGISPAVLTETIWTLAVEHPQPAIPAEIHVVTTLTGERTLRNRLFDTPDEEGLSVWARFCREVLQLDHEAPEAPQLHIHVPLRGNGLKLDDIRTWDDDRRYAELCYRVVARLCADPDAPRVVASIAGGRKTMSAHLLTAFSLYARPQDESIHVLVHPERPVLEDPTFFYPRPGSGTDVRIERVDLHLVRFRNQLEELARLHRGGQLPRTLQELESLPGLGLRPARPAEVEIVLGDRTERRLRLLDTEGRAMAQLQPVAPMPLVTLITLYEMLRRADSSEISNMQLVENEQVEALRNAAYAFCRDLAQLRPWGDTIALSRSISELNQLLAGNPLCNRYLRIHSRRTWEETFYAFGTEPPALRVCVPRALDYLQNWPFQYVPLTYLD
>NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein
MSEKLLTFLGVGDRNRQLEAQLQDRKYKRVRYFLPDTPDREIETPFVGQAILELHPDRFSQVVILGTVDSMWDTLLIHFLSDTQTEAEIDLYTELFEAIENKREAEVERLLPRLARVLEKRWRPGLQLKLIPVGRTQEELWRIFETLTGLKPSNTTLSIDITHGLRYQPFFLLLALQFFHLTRPGVRLGSVFYGALELHDYYAGRAPLFDLRPMLELMQWSLGAQAFVHYQDPEPLLELLRNTAQESLRHELRQFARQINLNLFNNFRERARKLSHQLRGLSQRQENLPAPFRLVEPFLVDFCETFASAKSDWEALLRLARRHLKYRRPALAVLAAHEAVVHRLGEVYGVNPAAKNPRGKRYGSQLVLTLKYPRVGRALPELKELVKAVDELQTIRNNTAHFRTDAEGPDPGYRLTKIRTLLTTLEEKLGHPALEQLPRLYPLERQ

Crispr_ID: NC_015970_5

• CRISPR_ID: NC_015970_5
• CRISPR_location: 72658-73245
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas1,cas2,cas6,csx1,csx20

Consensus repeat of NC_015970_5

Consensus_repeat	Method
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRT

spacers of NC_015970_5

>5.1|72695|38|NC_015970|PILER-CR,CRISPRCasFinder,CRT
GTAAACGCTCCCGAGAAGGTGTGGGATAAAGTGAAAGA
>5.2|72770|38|NC_015970|PILER-CR,CRISPRCasFinder,CRT
TGGAGGGGTTCAGAGGATGGGAATTTGCGGGCGGAGAA
>5.3|72845|39|NC_015970|PILER-CR,CRISPRCasFinder,CRT
TGAAATCGATCTTCGACTGGTCTAGCGACTCAAGCTTGA
>5.4|72921|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT
GGGACCCCCGTGTGTGCTGCAGCTTGTCTGCCACGCTGTGC
>5.5|72999|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CGTCTCCATTCTTCCACGAATGGAGAACCTGAAGTGGCGCCAGTCCA
>5.6|73083|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT
GTTTTCGTTGGGAATCGTGCATTCATCTGCAATGATATCCAGC
>5.7|73163|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CGAAGCCCGTGACAAGCTCGGGTGGCCGCTCAAGGTGGAATATCGT

CRISPR arrays and Neighbor proteins around NC_015970_5

CRISPR arrays

The CRISPR arrays of NC_015970_5

>merge|NC_015970|5|72658-73245|PILER-CR,CRISPRCasFinder,CRT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGTAAACGCTCCCGAGAAGGTGTGGGATAAAGTGAAAGAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTGGAGGGGTTCAGAGGATGGGAATTTGCGGGCGGAGAAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTGAAATCGATCTTCGACTGGTCTAGCGACTCAAGCTTGAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGGACCCCCGTGTGTGCTGCAGCTTGTCTGCCACGCTGTGCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCGTCTCCATTCTTCCACGAATGGAGAACCTGAAGTGGCGCCAGTCCAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGTTTTCGTTGGGAATCGTGCATTCATCTGCAATGATATCCAGCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCGAAGCCCGTGACAAGCTCGGGTGGCCGCTCAAGGTGGAATATCGTGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|5|4|72658-73245|PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTAAACGCTCCCGAGAAGGTGTGGGATAAAGTGAAAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGAGGGGTTCAGAGGATGGGAATTTGCGGGCGGAGAA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGAAATCGATCTTCGACTGGTCTAGCGACTCAAGCTTGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGGACCCCCGTGTGTGCTGCAGCTTGTCTGCCACGCTGTGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGTCTCCATTCTTCCACGAATGGAGAACCTGAAGTGGCGCCAGTCCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTTTTCGTTGGGAATCGTGCATTCATCTGCAATGATATCCAGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGAAGCCCGTGACAAGCTCGGGTGGCCGCTCAAGGTGGAATATCGT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|5|5|72658-73245|CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTAAACGCTCCCGAGAAGGTGTGGGATAAAGTGAAAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGAGGGGTTCAGAGGATGGGAATTTGCGGGCGGAGAA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGAAATCGATCTTCGACTGGTCTAGCGACTCAAGCTTGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGGACCCCCGTGTGTGCTGCAGCTTGTCTGCCACGCTGTGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGTCTCCATTCTTCCACGAATGGAGAACCTGAAGTGGCGCCAGTCCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTTTTCGTTGGGAATCGTGCATTCATCTGCAATGATATCCAGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGAAGCCCGTGACAAGCTCGGGTGGCCGCTCAAGGTGGAATATCGT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|5|4|72658-73245|CRT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTAAACGCTCCCGAGAAGGTGTGGGATAAAGTGAAAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGAGGGGTTCAGAGGATGGGAATTTGCGGGCGGAGAA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGAAATCGATCTTCGACTGGTCTAGCGACTCAAGCTTGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGGACCCCCGTGTGTGCTGCAGCTTGTCTGCCACGCTGTGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGTCTCCATTCTTCCACGAATGGAGAACCTGAAGTGGCGCCAGTCCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GTTTTCGTTGGGAATCGTGCATTCATCTGCAATGATATCCAGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGAAGCCCGTGACAAGCTCGGGTGGCCGCTCAAGGTGGAATATCGT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|135984
NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NC_015970.1|WP_029729972.1|68647_69637_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl|CDD|337605
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	gnl|CDD|274263
NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|187863
NC_015970.1|WP_014072544.1|65309_65708_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein	unknown	unknown	gnl|CDD|177543
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	unknown	unknown	gnl|CDD|214692
NC_015970.1|WP_014072550.1|73900_74221_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_015970.1|WP_014072549.1|73465_73840_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072546.1|69706_70573_-|J-domain-containing-protein	unknown	unknown	gnl|CDD|99751
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl|CDD|187817
NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845310.1|64803_65196_+|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	unknown
NC_015970.1|WP_012845312.1|65711_66077_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|350691

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.8e-21	70.9	0.0
NC_015970.1|WP_012845310.1|64803_65196_+|hypothetical-protein	csx20	cls000118_csx20_CAS-I:CAS-III	3.8e-73	238.6	0.0
NC_015970.1|WP_029729972.1|68647_69637_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	1.3e-100	331.5	1.4
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	1.2e-47	157.1	3.8
NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	3.6e-50	165.9	0.0
NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	9.6e-44	144.5	0.0
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	8.9e-99	325.2	0.0
NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	3.4e-70	231.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein	gnl|CDD|135984	PRK06642, PRK06642, single-stranded DNA-binding protein; Provisional.	6.79817e-05
NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	5.09194e-80
NC_015970.1|WP_029729972.1|68647_69637_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	6.72869e-07
NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	1.1845e-40
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00733985
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	gnl|CDD|214692	smart00487, DEXDc, DEAD-like helicases superfamily.	0.000608512
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	7.86656e-123
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	gnl|CDD|274263	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family. Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Archaea), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	8.28521e-39
NC_015970.1|WP_014072546.1|69706_70573_-|J-domain-containing-protein	gnl|CDD|99751	cd06257, DnaJ, DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.	1.73778e-07
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.40876e-21
NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein	gnl|CDD|187817	cd09686, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	9.00068e-41
NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein	gnl|CDD|177543	PHA03146, PHA03146, helicase-primase primase subunit; Provisional.	0.00996299
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	gnl|CDD|350691	cd17933, DEXSc_RecD-like, DEXS-box helicase domain of RecD and similar proteins. RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.8702e-34

Protein sequences

>NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1
MEAGQIYDAEVPEGPCWPVAWVYEFAYCLRRGYYAWVEGPGEPVALDTGEGVWLASDAWGGPVRWVQDGAGCPVPLLRVPRACADDSDRRPEHLMLAALADLVEAHTGQPVRRGLVLDATTGRREEITLDETLRAAWQSLDRRIRAVIHEGSVPPPRADGRCHHCPRLEVCRPFFGHAEEAAVAIMPPVRQARTLYVDEIGAVVRRKGRQLVVTVSRDGRRQELLRVPALLVDQVVLVGPVQITSQALRMLLRRNVDIVYLSGEGRFEGRLAAEFHPHVALRLAQYEAFRDPERTLTLARLFVRGKLQNMAGLLRRYADEYGSASLRAAASEINRDLERLEQVTTLEALRGVEGTASRRYFSVFGEMLRAEAHAPTGWPAFPGRNRRPPTDPVNATLGYLYALLLGNVVAACALAGLDPYVGYLHAPAYGRPSLALDLMEEFRAPAADRLALRLFNRGRLRPQHFEERNGGVYLNEAGRAVVLEAWQAHRQQTSAHPVLGMELSLARHFEAQARLLARALQEQGIAYTPFVA
>NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2
MAFWLVGYDIAEPRRLQRVARLLEDYGQRLHYSVFLCRLEAGEMRRLRQGLLHIVDLEEDRLFFLRLCRGCIDALEQMGQGRGIDPRQDHWIV
>NC_015970.1|WP_014072546.1|69706_70573_-|J-domain-containing-protein
MEQLERAHDLIEKGKHREAYLLLGECVDRALRELEADRRARRNGFVLGLGVSLLTGGLGLEDLIWGPLAYKVARTFSGGTMKPEEAGQLLIEALNLRIFLLENMPEFMTDVEESSRVLRDILLLYLMLKQKDELFDQLLPQLIGHPDPWLVVRHLSGEIGDKNFYDLDTLLFICLFLYDLRRGELYGKLYRKLRRGRESLEQELERIRRKKSGDFEGLDAALEQHYAAVLELKAPYTAEKVRRNYRRLIKACHPDRMQQASAEERRRAEERARELNEAYEYFRARLNF
>NC_015970.1|WP_029729972.1|68647_69637_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MYASMLNETGLARLRWSVVRFELAVSSPVDLGDLPASTVRGALGAALRRMVCITRLPACTDCPFRWPCIYGYLFETPPSPDGRYLRGLQDVPRPYVVRRPGLEERRFAPGERLTVELRLVGRARMYLPYLTLALVRLEENGLGRGRREGGGRFRLASAHALRPDGSLQQVYDAATRQVLAEVPEWSAAELLADEQPAEVARLRAIAPLRLKAQGRLVRQLTYRVLLRSVLSRLSSLAAFHAETELKLDYAGLLRRAEAVRVREDRMQWRDDLQRYSGRQRTTMRQGGLVGEIIFEGVPPETWPLLRLGAELHVGHSTVMGLGAYELLPL
>NC_015970.1|WP_012845314.1|67321_68662_+|TIGR02221-family-CRISPR-associated-protein
MSEKLLTFLGVGDRNRQLEAQLQDRKYKRVRYFLPDTPDREIETPFVGQAILELHPDRFSQVVILGTVDSMWDTLLIHFLSDTQTEAEIDLYTELFEAIENKREAEVERLLPRLARVLEKRWRPGLQLKLIPVGRTQEELWRIFETLTGLKPSNTTLSIDITHGLRYQPFFLLLALQFFHLTRPGVRLGSVFYGALELHDYYAGRAPLFDLRPMLELMQWSLGAQAFVHYQDPEPLLELLRNTAQESLRHELRQFARQINLNLFNNFRERARKLSHQLRGLSQRQENLPAPFRLVEPFLVDFCETFASAKSDWEALLRLARRHLKYRRPALAVLAAHEAVVHRLGEVYGVNPAAKNPRGKRYGSQLVLTLKYPRVGRALPELKELVKAVDELQTIRNNTAHFRTDAEGPDPGYRLTKIRTLLTTLEEKLGHPALEQLPRLYPLERQ
>NC_015970.1|WP_012845313.1|66130_67315_+|TIGR02584-family-CRISPR-associated-protein
MERYNLLIALGISPAVLTETIWTLAVEHPQPAIPAEIHVVTTLTGERTLRNRLFDTPDEEGLSVWARFCREVLQLDHEAPEAPQLHIHVPLRGNGLKLDDIRTWDDDRRYAELCYRVVARLCADPDAPRVVASIAGGRKTMSAHLLTAFSLYARPQDESIHVLVHPERPVLEDPTFFYPRPGSGTDVRIERVDLHLVRFRNQLEELARLHRGGQLPRTLQELESLPGLGLRPARPAEVEIVLGDRTERRLRLLDTEGRAMAQLQPVAPMPLVTLITLYEMLRRADSSEISNMQLVENEQVEALRNAAYAFCRDLAQLRPWGDTIALSRSISELNQLLAGNPLCNRYLRIHSRRTWEETFYAFGTEPPALRVCVPRALDYLQNWPFQYVPLTYLD
>NC_015970.1|WP_012845312.1|65711_66077_+|hypothetical-protein
MRVWLTNFFAREVPCTLEISVTLEGGEHPPQLVDFLRKRADRLWTNPDGSMLAIFIREFRLESLQERLPWFLRALELRLLRLGACHGTLAWRPAFAYDWSLEGRGCSRERALEQLLRLQRN
>NC_015970.1|WP_014072544.1|65309_65708_+|hypothetical-protein
MRTTHNLILYITDMEPADLRTAERLIEAFEEELGCVLEYDPEHRMLSLHTAMVVEPAEASGAALRQMLHCIRHLAGRFLQEYRLIFSVSARSSASGSRPLGTVLERSPYDRLLSQLITPEYPRLLPPEPPLC
>NC_015970.1|WP_012845310.1|64803_65196_+|hypothetical-protein
MLINLSNHPASTWGKAQREASRMYGEVEDWPFPLIPPEWDAHQVAGLAQDYAERIVRRLNEAGGGRHAVHVMGEMTFTCTLVRLLHQRGILCLASTSQRIVEEDPASGKKIACFRFERFRPYPCLQALSF
>NC_015970.1|WP_012845309.1|63542_64823_+|TIGR02221-family-CRISPR-associated-protein
MERVLLSFIGTGNYQPCIYVWGDHRCKTPYFQEAAVRFFNPDQCLVLMTEMAQKKHGAALRRRIKRIVYQRSKKARAACNSKNALRKRIKRIVYRPVSIPDGRNEDELWAIFSALTDCIPEGATLIVDVTHGFRTQPMLALAALCYLRVARNVQIERIIYGAFEARHPDTSEAPVFDLTPFLTLIDWSVAAHQFIHYGQANDLARLIREIHRLTYVEQAQVQAQHAATAASWLEGFARALGLVRLAEVMTEHALRLPEALERMRQDVDQIARLRPFGLLLDITAERARSLHHPDPLSLDGLRLQAELIRHLLNYGLVQQAVTVAREAIVTRYALDLGRDPLQEREAVEHELGRLASGLQDPAVRAGYTPETHQLAELWNRLTNVRNDINHAGMRTNPETTNNLYRLASECAEAAANWIARDAHQPE
>NC_015970.1|WP_014072549.1|73465_73840_-|hypothetical-protein
MACPVLLEFEIYIEGESDLEKDLEGLRQRLPEAEVKAYPRVFDLEVSCLVEVEAERIYDEVDRICETIKDWASSHLNGRRPCASIKWDVPRMLKGRMRVRYEEAREFMSRRREHICAQVQQHCN
>NC_015970.1|WP_014072550.1|73900_74221_-|hypothetical-protein
MRTSYRFTLHYRGRNPALMPALIRSLSQMGYGPVTGPVFTWTFEQPRLDEVLKKLQHRICRELARSGAPGEEVTVTYGPAAIAAGYVELFGEELSPDMEDWPELSR
>NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein
MEPIKPGRTVNRVILLGRLAEPPTPVPGAGEACQMILTTEERGRNAAGEPIMRLERHLLLIEEPGLTAFCLQHLQVGMTLYVEGSLRRNENPATDSIPVAVWVRRLMVASWDPGGLPDDPPV
>NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein
MNDFWYDGDFEFGDEFEGDFESDDYEGFQDLPDHRDWEEDWDEEWDDWDDELDDGRATCDFCGAPVGRYGYDDGYLTLCEDCRDQMYGD
>NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase
MEKLSNEQQRVLDHVLAWLERNDAPPIFILTGSAGTGKTLLIRHLVRALQDRRIHYALAAPTGRAARILSERTGDHARTLHSLIYIFDRYQLVEEADRQTDEPLSLQLHFALRSAEHDARLIIVDEASMVSDTAGEEELYRFGSGRLLNDLLTFARLIPKRDRPPITRLLFVGDPAQLPPVGQSVSPALSAQYLRDTFGLSAETAHLRSVYRQRKGHPILEAATALRNALEKGHYHTFRLPEQPPDLRPVGLEEAIETTATDFRRQNPSVLLCRTNALARKLNAAVRARLWGREGLPPQPGDLLLVNRNAPLHGLFNGDLVLVETVGPLEHRRVGRRGRPPVDLYFRDVELLYPHEKPRNRIRCKLLENLLESPDGQLSPDIIQALLIDFYRRHPSLKHGSSEFRLMLANDAYFNALHVRYGYAMTVHKAQGGEWKRATVVFNDWRHFRHAEFFRWAYTAITRAREELLTIGAPSFEALSDMRWQPAPSVPAPEQAAENATRFPLKALEAYHQRLSEALTAAGIETTGVELLQYAVRYHLARADRTTRIQYYYRGDGQISRIVTLGGADDPELTQQAYALFERILSEPPADSGELPENPLLREFLERAHLRLEGSGIRIVHWKEMPYALRLYFSADGENVTIDFYYNRRGVWTHAQEVGRSSSGALFARIQSLLQADS
>NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein
MTSEVPTEVIQQFHALCQRQDFKSALPLARHLRPMLIRDRRLANTWGWVLYRQLKNLQQRLQQKDGRAANNLPEHLAQQVREILVEYARLPNLHRPDLLHALMLATVCRIGTRWRGILGFLYYVRAFDTLRPEDRRPRTLQQRTYPSLEQQLTRTVAAALAKLPLEDQRPEVLNWASTQVQQRLSRFPDEPWIPYHLACYLIKKQRISEARPLLAPVLLQHHQKSWIWEKVARANQDRPAHRLTALTQALRLATKEHPVVRFRLHLYLAELLAAEQRYDEAAAQLQAARRLEKELGRNEQDRRNPLWRSYRQMLQQPWFRQRAERTDLPQEPALTIQPDVILYEHQPLQEAFGVVIHHNPDRNRTLIRLSPSEVVSVKHRRFPQASRLEPGTVVWLCLAEKRVVALEPRAGHPLPDLVRRFRGRLLQPEGRAFAFVLTEDNERIFIAPGLNRQLALEAGAMVEVLAERTIDPKKKMLSWSALKVEPVADR
>NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein
MERFWFLFAIGSLAFLIYRYNQICRKNPGLNRQVYAFTLALFLIVFIVANIYEYICAAPLFVIYLIFLLKTFFDHDKILALSALITVVASFNLMLENISVFSSFFLLAWLAFIFTVFHRKDSANSKALDGSGRRNSSDSENDRNVRLPVKAERRELELIRKTRGDLENRRFLALRVRSMRL
>NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein
MRRIALLFGLLLALPLRAQPTFDLLGGLGPARLGAGQNRSAMHGWFAAGGHLPSGVGGFLVVDLLQATAPEQSGIIWEGGYALSGVATVVAYRMTSRRLLFGTLAGPGLWQLSIDASVSGVNTAVKDHTAIGFLLGGYGLVRLGGTFTAGLLFTRRWTATEPSSVGCFVECLSRTIGNGHAGGSGLSVVIGATIR
>NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein
MRVRFLLVRLPFQQSMVLVMKELEGEQRVAIVPVVAPGETFHEEQAYRIFQEVAAGRLPAGAEELGEFEFPDEEAAQEAARDFVKNLKESLWGEVEAFGEKQQPSSVDTVLLLTVGGSTEPLVHAIRNLDLARSRVLFICSPDSRTLVEGGEGIMQRLPDMAGLERSRYDVMVWKDPDDLAGCVAALFELYRQIRREYPGARIAANYTGGTKTMSAALVIGAVLLGWELQLNVGVRQDLRQVLAGTDVPTRVAADDVLLRLELRLVRQALDRYDYGAAEGLVQEWLRTLSLGGERRTQVLLLYQIVRGLAAWDLGQYRQALVSFGLAGEHGASWLPRLRVLAEGQEDTFELVADLLLGAARRAHQRRYDDAVVRLLRALELFGTIRLRQAHGLDVGQLEPARLPERLRETLASTGYRGAVEVETVYRLLEALGDPVGRLFAKRRTSLLEALEQSRHSRLIGGNFSIDEQTYGVVRSRLEGFLHEAARLTDQTLQAPQLPRSEVLDWVGLE
>NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein
MRRLGIILRQIAARGRPNRIKNCRNPENRGWLRTPMGGGGSGMHFYLWWAQSDSERVAPLAPTENEVFLRTIRHHDEHTPLDCGHRDDYIHLSLQELQTERIDGVDCSPWTPEQRAFIEAGEAVRIILGRPGSGKTASLWRAVERHPARHLLYLTWSRELAWQAHLNFSALTPDRTIRCWHFTRLLRALTQQDEPRLTLSESRRRFREAL

Crispr_ID: NC_015970_6

• CRISPR_ID: NC_015970_6
• CRISPR_location: 79804-79997
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas1,cas2,csx1,cas14j

Consensus repeat of NC_015970_6

Consensus_repeat	Method
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCGCCTG	PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRISPRCasFinder

spacers of NC_015970_6

>6.1|79847|35|NC_015970|PILER-CR
GTCAGCGGAACGCTCTACTACAACCCATATACAGA
>6.2|79925|36|NC_015970|PILER-CR
TGTTGGCCTCGCTGGAGCAATGGGCCAGCGAACATG
>6.3|79841|41|NC_015970|CRISPRCasFinder
CGCCTGGTCAGCGGAACGCTCTACTACAACCCATATACAGA
>6.4|79919|36|NC_015970|CRISPRCasFinder
TGTTGGCCTCGCTGGAGCAATGGGCCAGCGAACATG

CRISPR arrays and Neighbor proteins around NC_015970_6

CRISPR arrays

The CRISPR arrays of NC_015970_6

>merge|NC_015970|6|79804-79997|PILER-CR,CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCGCCTGGTCAGCGGAACGCTCTACTACAACCCATATACAGAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTGTTGGCCTCGCTGGAGCAATGGGCCAGCGAACATGGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGACCGCGTG

>NC_015970|6|5|79804-79997|PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCGCCTG	GTCAGCGGAACGCTCTACTACAACCCATATACAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTGTTGG	CCTCGCTGGAGCAATGGGCCAGCGAACATGGTCGTA
ATCCCCTTTTCATCGGGTCAAGTTTTCGGACCGCGTG

>NC_015970|6|6|79804-79992|CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CGCCTGGTCAGCGGAACGCTCTACTACAACCCATATACAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGTTGGCCTCGCTGGAGCAATGGGCCAGCGAACATG
GTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|135984
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	gnl|CDD|223747
NC_015970.1|WP_014072546.1|69706_70573_-|J-domain-containing-protein	unknown	unknown	gnl|CDD|99751
NC_015970.1|WP_014072549.1|73465_73840_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	unknown	unknown	gnl|CDD|214692
NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	gnl|CDD|274263
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	unknown	unknown	gnl|CDD|99825
NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072550.1|73900_74221_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein	unknown	unknown	gnl|CDD|177543
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|350691
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl|CDD|223588

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.8e-21	70.9	0.0
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	3.8e-74	245.2	0.0
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	8.9e-99	325.2	0.0
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	1.2e-47	157.1	3.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein	gnl|CDD|135984	PRK06642, PRK06642, single-stranded DNA-binding protein; Provisional.	6.79817e-05
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.96239e-48
NC_015970.1|WP_014072546.1|69706_70573_-|J-domain-containing-protein	gnl|CDD|99751	cd06257, DnaJ, DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.	1.73778e-07
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00733985
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	gnl|CDD|214692	smart00487, DEXDc, DEAD-like helicases superfamily.	0.000608512
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	7.86656e-123
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	gnl|CDD|274263	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family. Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Archaea), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	8.28521e-39
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	gnl|CDD|99825	cd05782, DNA_polB_like1_exo, Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases. A subfamily of the 3'-5' exonuclease domain of family-B DNA polymerases. This subfamily is composed of uncharacterized bacterial family-B DNA polymerases. Family-B DNA polymerases contain an N-terminal DEDDy DnaQ-like exonuclease domain in the same polypeptide chain as the polymerase domain, similar to family-A DNA polymerases. This exonuclease domain contains three sequence motifs termed ExoI, ExoII and ExoIII, with a specific YX(3)D pattern at ExoIII. These motifs are involved in metal binding and catalysis. The exonuclease domain of family-B DNA polymerases has a fundamental role in proofreading activity. It contains a beta hairpin structure that plays an important role in active site switching in the event of a nucleotide misincorporation. Family-B DNA polymerases are predominantly involved in DNA replication and DNA repair.	1.73355e-25
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.40876e-21
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	gnl|CDD|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	3.89161e-83
NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein	gnl|CDD|177543	PHA03146, PHA03146, helicase-primase primase subunit; Provisional.	0.00996299
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00313624
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00904018
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	gnl|CDD|350691	cd17933, DEXSc_RecD-like, DEXS-box helicase domain of RecD and similar proteins. RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.8702e-34

Protein sequences

>NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein
MERFWFLFAIGSLAFLIYRYNQICRKNPGLNRQVYAFTLALFLIVFIVANIYEYICAAPLFVIYLIFLLKTFFDHDKILALSALITVVASFNLMLENISVFSSFFLLAWLAFIFTVFHRKDSANSKALDGSGRRNSSDSENDRNVRLPVKAERRELELIRKTRGDLENRRFLALRVRSMRL
>NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein
MTSEVPTEVIQQFHALCQRQDFKSALPLARHLRPMLIRDRRLANTWGWVLYRQLKNLQQRLQQKDGRAANNLPEHLAQQVREILVEYARLPNLHRPDLLHALMLATVCRIGTRWRGILGFLYYVRAFDTLRPEDRRPRTLQQRTYPSLEQQLTRTVAAALAKLPLEDQRPEVLNWASTQVQQRLSRFPDEPWIPYHLACYLIKKQRISEARPLLAPVLLQHHQKSWIWEKVARANQDRPAHRLTALTQALRLATKEHPVVRFRLHLYLAELLAAEQRYDEAAAQLQAARRLEKELGRNEQDRRNPLWRSYRQMLQQPWFRQRAERTDLPQEPALTIQPDVILYEHQPLQEAFGVVIHHNPDRNRTLIRLSPSEVVSVKHRRFPQASRLEPGTVVWLCLAEKRVVALEPRAGHPLPDLVRRFRGRLLQPEGRAFAFVLTEDNERIFIAPGLNRQLALEAGAMVEVLAERTIDPKKKMLSWSALKVEPVADR
>NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase
MEKLSNEQQRVLDHVLAWLERNDAPPIFILTGSAGTGKTLLIRHLVRALQDRRIHYALAAPTGRAARILSERTGDHARTLHSLIYIFDRYQLVEEADRQTDEPLSLQLHFALRSAEHDARLIIVDEASMVSDTAGEEELYRFGSGRLLNDLLTFARLIPKRDRPPITRLLFVGDPAQLPPVGQSVSPALSAQYLRDTFGLSAETAHLRSVYRQRKGHPILEAATALRNALEKGHYHTFRLPEQPPDLRPVGLEEAIETTATDFRRQNPSVLLCRTNALARKLNAAVRARLWGREGLPPQPGDLLLVNRNAPLHGLFNGDLVLVETVGPLEHRRVGRRGRPPVDLYFRDVELLYPHEKPRNRIRCKLLENLLESPDGQLSPDIIQALLIDFYRRHPSLKHGSSEFRLMLANDAYFNALHVRYGYAMTVHKAQGGEWKRATVVFNDWRHFRHAEFFRWAYTAITRAREELLTIGAPSFEALSDMRWQPAPSVPAPEQAAENATRFPLKALEAYHQRLSEALTAAGIETTGVELLQYAVRYHLARADRTTRIQYYYRGDGQISRIVTLGGADDPELTQQAYALFERILSEPPADSGELPENPLLREFLERAHLRLEGSGIRIVHWKEMPYALRLYFSADGENVTIDFYYNRRGVWTHAQEVGRSSSGALFARIQSLLQADS
>NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein
MNDFWYDGDFEFGDEFEGDFESDDYEGFQDLPDHRDWEEDWDEEWDDWDDELDDGRATCDFCGAPVGRYGYDDGYLTLCEDCRDQMYGD
>NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein
MEPIKPGRTVNRVILLGRLAEPPTPVPGAGEACQMILTTEERGRNAAGEPIMRLERHLLLIEEPGLTAFCLQHLQVGMTLYVEGSLRRNENPATDSIPVAVWVRRLMVASWDPGGLPDDPPV
>NC_015970.1|WP_014072550.1|73900_74221_-|hypothetical-protein
MRTSYRFTLHYRGRNPALMPALIRSLSQMGYGPVTGPVFTWTFEQPRLDEVLKKLQHRICRELARSGAPGEEVTVTYGPAAIAAGYVELFGEELSPDMEDWPELSR
>NC_015970.1|WP_014072549.1|73465_73840_-|hypothetical-protein
MACPVLLEFEIYIEGESDLEKDLEGLRQRLPEAEVKAYPRVFDLEVSCLVEVEAERIYDEVDRICETIKDWASSHLNGRRPCASIKWDVPRMLKGRMRVRYEEAREFMSRRREHICAQVQQHCN
>NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1
MEAGQIYDAEVPEGPCWPVAWVYEFAYCLRRGYYAWVEGPGEPVALDTGEGVWLASDAWGGPVRWVQDGAGCPVPLLRVPRACADDSDRRPEHLMLAALADLVEAHTGQPVRRGLVLDATTGRREEITLDETLRAAWQSLDRRIRAVIHEGSVPPPRADGRCHHCPRLEVCRPFFGHAEEAAVAIMPPVRQARTLYVDEIGAVVRRKGRQLVVTVSRDGRRQELLRVPALLVDQVVLVGPVQITSQALRMLLRRNVDIVYLSGEGRFEGRLAAEFHPHVALRLAQYEAFRDPERTLTLARLFVRGKLQNMAGLLRRYADEYGSASLRAAASEINRDLERLEQVTTLEALRGVEGTASRRYFSVFGEMLRAEAHAPTGWPAFPGRNRRPPTDPVNATLGYLYALLLGNVVAACALAGLDPYVGYLHAPAYGRPSLALDLMEEFRAPAADRLALRLFNRGRLRPQHFEERNGGVYLNEAGRAVVLEAWQAHRQQTSAHPVLGMELSLARHFEAQARLLARALQEQGIAYTPFVA
>NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2
MAFWLVGYDIAEPRRLQRVARLLEDYGQRLHYSVFLCRLEAGEMRRLRQGLLHIVDLEEDRLFFLRLCRGCIDALEQMGQGRGIDPRQDHWIV
>NC_015970.1|WP_014072546.1|69706_70573_-|J-domain-containing-protein
MEQLERAHDLIEKGKHREAYLLLGECVDRALRELEADRRARRNGFVLGLGVSLLTGGLGLEDLIWGPLAYKVARTFSGGTMKPEEAGQLLIEALNLRIFLLENMPEFMTDVEESSRVLRDILLLYLMLKQKDELFDQLLPQLIGHPDPWLVVRHLSGEIGDKNFYDLDTLLFICLFLYDLRRGELYGKLYRKLRRGRESLEQELERIRRKKSGDFEGLDAALEQHYAAVLELKAPYTAEKVRRNYRRLIKACHPDRMQQASAEERRRAEERARELNEAYEYFRARLNF
>NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein
MRRIALLFGLLLALPLRAQPTFDLLGGLGPARLGAGQNRSAMHGWFAAGGHLPSGVGGFLVVDLLQATAPEQSGIIWEGGYALSGVATVVAYRMTSRRLLFGTLAGPGLWQLSIDASVSGVNTAVKDHTAIGFLLGGYGLVRLGGTFTAGLLFTRRWTATEPSSVGCFVECLSRTIGNGHAGGSGLSVVIGATIR
>NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein
MRVRFLLVRLPFQQSMVLVMKELEGEQRVAIVPVVAPGETFHEEQAYRIFQEVAAGRLPAGAEELGEFEFPDEEAAQEAARDFVKNLKESLWGEVEAFGEKQQPSSVDTVLLLTVGGSTEPLVHAIRNLDLARSRVLFICSPDSRTLVEGGEGIMQRLPDMAGLERSRYDVMVWKDPDDLAGCVAALFELYRQIRREYPGARIAANYTGGTKTMSAALVIGAVLLGWELQLNVGVRQDLRQVLAGTDVPTRVAADDVLLRLELRLVRQALDRYDYGAAEGLVQEWLRTLSLGGERRTQVLLLYQIVRGLAAWDLGQYRQALVSFGLAGEHGASWLPRLRVLAEGQEDTFELVADLLLGAARRAHQRRYDDAVVRLLRALELFGTIRLRQAHGLDVGQLEPARLPERLRETLASTGYRGAVEVETVYRLLEALGDPVGRLFAKRRTSLLEALEQSRHSRLIGGNFSIDEQTYGVVRSRLEGFLHEAARLTDQTLQAPQLPRSEVLDWVGLE
>NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein
MRRLGIILRQIAARGRPNRIKNCRNPENRGWLRTPMGGGGSGMHFYLWWAQSDSERVAPLAPTENEVFLRTIRHHDEHTPLDCGHRDDYIHLSLQELQTERIDGVDCSPWTPEQRAFIEAGEAVRIILGRPGSGKTASLWRAVERHPARHLLYLTWSRELAWQAHLNFSALTPDRTIRCWHFTRLLRALTQQDEPRLTLSESRRRFREAL
>NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein
MSAPQLGPWKHRLTALHAELRAFLIGRARPGHTSTVFDGRVFHLRPEAYAGLRQNDRHPEAIEKAWHVFELLGRDERLAEIFPELALASLAIRTLQAGRLPAVLDTIEGIVVDEVQDLTLLELSVVVELWRRLAQRRPEPPLLLLAGDEGQTVRPSGFRWGPYKDWLSERIAPPRDYELGESLRCPANIVRTFDRAARYYRKLPREERPARQRRDSPAAPGGHLIYVATENQQQAASLIHELCEEEALVVVSLEDEVPEHIWSPALIKGLERQTVVVLNPGAVLERLDRFVSEENFAFDREDYRTEVDRLRVALSRSSETLVFLDVAPTAAQRACSLRLLGDDAVEVAPHELLNSLEQAELSLLERIQARLEEFTARIDEDPSQALQLALRARELQLRIQSLGEHIPARIAREVSRAILSATARLLVDDHPTEVDAPELQQAREAARELGLEHLRALDELVRWHRSGRTFPAALLQAACQLPDEAEWLRQALSAIAYSLHAALEHGARSPESAAVFLEDVASWLRFLDYGGNVEEAVRRLRGLAFDALLAAGNLATAEQLLEHIHPPDLLRKGRLLEARDALEEAIEVYLQAGAHTEAERVRQRLYHFRNHTLQRFRRLADQCSDPEQIPVLISMLSGAQQRLAFWYIRLCLETKHGSDDQSPLHPFLGYLEAVHAHAELLEDPELMMLGALEELSRRRHRACGAATRLLFERFGTRSMARRLLASPIGELPECSEPAVFCLAASVLETLRNCPPYQKLLAFSDHGKPTRGPAES
>NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein
MSRLRDATLLLTEAQQGVDQVLRGCQHLNDRVADLFEHLHAAANALQEAGFPELKERLDQQKTDLEKLQERQQEALRQFDALRKTLEYLHQSILRLAAGYNSLQLRLQATGEQLQTGFESLMLATSRLTDRIAAIETRQQRSLWTLAAVAGLVLLTLIVVLWP
>NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein
MNEGDRILEAERQIRQLAEELDRLFRAANLLKSAQEQLDEVAQSSRRLVEETGKFITTAGDIVARLSEADLPRQIEAITQQVREAHERLLATLQEHVAALQSLEEEESGRLRERLENLERLQEDRFEQLRDLLGAIQKGQHEGVSALREAIQQNTTAIRSLMEEESGRLRETLKALQTRVTLVLATLGVIILLLLLLIFRAG
>NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase
MDRYWYSAAARLGLWDTLPEAQQGLVNNLYRRLRFYAHAVLEGYEAFAFDKTESESLSSLLAVIDKLTIRGCPTLVDLDLETALLEGPCRQFVDAVPIEDGPVVGWKFRRFLLPVQFSDLIRATVELLELPFSSNGKDGTDDLAYPVITPELEALSSEEEHLFIEQFANVFGSHLLRKLRRQVPLQDLVPYELEEPFVRQRVDFALQIGRLRYVFEIDGRQHLEPGQRRLDDQRDQLLKNAGWQVIRIPVEVVRQGRGSQLQTLHDRLREAQLEGLEQIGRTSVLDLVASSDLYRAALYGWIYPLAVHRCLRGLAFLYRFGYLDAGRPQRVLVIEEDIPVVASAFRILHTYWDHLRALAPEVPPPPTLEVDVIGCDEIEILAPVEGTRRVTAPSGSYDLVLDHSFWLYDGSEGPLEKELQPLPPGRYVRLRRAFGLREERSLTWSAALHYDLGDLERALIAEAEGRPAEMPERKVAALRFFLQQIFRKRDFWEGQLRVIARLLQGRPTVVLLPTGGGKSLTYQYSGMLLPGMTIVVDPLISLMIDQVDNLRGFAIDMVASISSIIDTEARERIIAQMGAGKLAYVFISPERLQSDDFRQKLQDVAARLPISLAVVDEAHCVSEWGHDFRPSYLHMTHNLQKFCASAASRPTLVALTGTASFAVLTDIQAELGITDESAIVLPRSFDRKEIRFHVERVPREAKMHALKRFRSQLPYLLRVNPQRFFELSGAETNCGIVFCPHVNGELGVWEVALELGHGKCYAGKQPRSFNEQRHGKWPDFKLKVQKDFKHNRIQEIVATKSFGMGIDKPNIRYTIHICIPHSVEAFYQEAGRAGRNGKPGYAISAILYSDENWVEAMGIFNEADHRKAQKKIENIPWNSRGDLLIQLWLLYNTYRGRDDEYQRALDFWKRYVRPELKELPVGATRLLEIPFTQSRRVDDEEEETNRGALEKSIFRMVILRIVEDYTIDWNQSIFQLRVRNAAPIEIKQSLRNYLGRYKLPATADQMVQPIPEDDQEKALEAALEVLIDFVYGEIAAKRKQALRTMAELCRNFRSDRDFREAILAYLQESEFSAELRTWIGRGFDEIGLEKIRDLLGKLSSLDEIKRLVGTTRRMLDEDPGNVPLRYLSAVARALSRVESEESVLEEVVSLTLQILRLKDRLRDPDEILAALLGDLATARPELLARAADRVLRLFGTPALARRLLQGPAGSDAVVRNHAAVLLMAESLRTIRESAFYQTLVNAV
>NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease
MHLRRKREPDVVEEAIIQQKAASLHPLLGWIVCISVQRAVDNPFQPNPPHSYLAPTPDDERDMLERFWHDVQQFVDRRERICWITFNGKRFDVPFLLARTLHHGLAPVQCDLLDTYPYNQYPHCDLSKLFEGINLGLADLCALLNVSNPKEYGDGNQVQHMLETEGIEAVRRYCEADVEATMQCFARLLPLLPPACQPRG
>NC_015970.1|WP_014072560.1|93544_94675_-|transposase
MRTTFKYRLYRSKRDKHLIEQIEVAASIWNHSVALTRRYYRIYGKYPGANRLMKHIARLRRRNPYWQKLGSQAVQDVIQRLDRAYWRFFSDPKAGRPRFKKRERYSSFTLKQAGWKYPGGNRIRIGKHNYKFVLSRPIQGEIKTVTIKRDRVGRLWICFSVVTEEQPKPPAPHEAVMRPVGLDFGLKCFLTLSDGTKIQSPEFFRRGLQEVRKAHRALSRKQRGSNNYRKARVRLAKVYDRISNQRRDWFFKTAHALCERYDFIALEDLNIEGMKRRWGRKVSDLGFGEFVSILEHVARKRGVRVAKVARFFPSSRRCSCCGWVKENLSLADREWTCERCGTVHDRDENAAINICREGASSLGVGDVRPPEAAVAV
>NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein
MLKNKRPDSLWKDMLSLLNTLGEEELDILAQLIIALLTARKKFSLAEEPESDADAAKSPAGSASSRQKKKRVTIRVEYRKCGKDCRCNGGRGHGPYRYMYWVENGRLRSRYLGRA

Crispr_ID: NC_015970_7

• CRISPR_ID: NC_015970_7
• CRISPR_location: 80646-80845
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas1,cas2,csx1,cas14j

Consensus repeat of NC_015970_7

Consensus_repeat	Method
AGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC	PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRISPRCasFinder

spacers of NC_015970_7

>7.1|80684|40|NC_015970|PILER-CR
GAAAGCACGGATACCAGATGTCGTGAAGAAGAGACATATC
>7.2|80762|46|NC_015970|PILER-CR
TCGGGTCGTGATCGTCAGCGTGTTGGCGTTGCCGAGGCCGAATGGG
>7.3|80684|41|NC_015970|CRISPRCasFinder
GAAAGCACGGATACCAGATGTCGTGAAGAAGAGACATATCA
>7.4|80762|47|NC_015970|CRISPRCasFinder
TCGGGTCGTGATCGTCAGCGTGTTGGCGTTGCCGAGGCCGAATGGGC

CRISPR arrays and Neighbor proteins around NC_015970_7

CRISPR arrays

The CRISPR arrays of NC_015970_7

>merge|NC_015970|7|80646-80845|PILER-CR,CRISPRCasFinder
AGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGACGAAAGCACGGATACCAGATGTCGTGAAGAAGAGACATATCAGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGACTCGGGTCGTGATCGTCAGCGTGTTGGCGTTGCCGAGGCCGAATGGGCGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC

>NC_015970|7|6|80646-80845|PILER-CR
AGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC	GAAAGCACGGATACCAGATGTCGTGAAGAAGAGACATATC
AGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC	TCGGGTCGTGATCGTCAGCGTGTTGGCGTTGCCGAGGCCGAATGGG
CGTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC

>NC_015970|7|7|80647-80845|CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC	GAAAGCACGGATACCAGATGTCGTGAAGAAGAGACATATCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC	TCGGGTCGTGATCGTCAGCGTGTTGGCGTTGCCGAGGCCGAATGGGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTTTTCGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|135984
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	gnl|CDD|223747
NC_015970.1|WP_014072549.1|73465_73840_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	unknown	unknown	gnl|CDD|214692
NC_015970.1|WP_014072550.1|73900_74221_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	gnl|CDD|274263
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	unknown	unknown	gnl|CDD|99825
NC_015970.1|WP_014072561.1|95831_96767_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein	unknown	unknown	gnl|CDD|177543
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|350691
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl|CDD|223588

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.8e-21	70.9	0.0
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	3.8e-74	245.2	0.0
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	8.9e-99	325.2	0.0
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	1.2e-47	157.1	3.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein	gnl|CDD|135984	PRK06642, PRK06642, single-stranded DNA-binding protein; Provisional.	6.79817e-05
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.96239e-48
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00733985
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	gnl|CDD|214692	smart00487, DEXDc, DEAD-like helicases superfamily.	0.000608512
NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	7.86656e-123
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	gnl|CDD|274263	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family. Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Archaea), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	8.28521e-39
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	gnl|CDD|99825	cd05782, DNA_polB_like1_exo, Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases. A subfamily of the 3'-5' exonuclease domain of family-B DNA polymerases. This subfamily is composed of uncharacterized bacterial family-B DNA polymerases. Family-B DNA polymerases contain an N-terminal DEDDy DnaQ-like exonuclease domain in the same polypeptide chain as the polymerase domain, similar to family-A DNA polymerases. This exonuclease domain contains three sequence motifs termed ExoI, ExoII and ExoIII, with a specific YX(3)D pattern at ExoIII. These motifs are involved in metal binding and catalysis. The exonuclease domain of family-B DNA polymerases has a fundamental role in proofreading activity. It contains a beta hairpin structure that plays an important role in active site switching in the event of a nucleotide misincorporation. Family-B DNA polymerases are predominantly involved in DNA replication and DNA repair.	1.73355e-25
NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.40876e-21
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	gnl|CDD|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	3.89161e-83
NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein	gnl|CDD|177543	PHA03146, PHA03146, helicase-primase primase subunit; Provisional.	0.00996299
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00313624
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00904018
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	gnl|CDD|350691	cd17933, DEXSc_RecD-like, DEXS-box helicase domain of RecD and similar proteins. RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.8702e-34

Protein sequences

>NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein
MRRIALLFGLLLALPLRAQPTFDLLGGLGPARLGAGQNRSAMHGWFAAGGHLPSGVGGFLVVDLLQATAPEQSGIIWEGGYALSGVATVVAYRMTSRRLLFGTLAGPGLWQLSIDASVSGVNTAVKDHTAIGFLLGGYGLVRLGGTFTAGLLFTRRWTATEPSSVGCFVECLSRTIGNGHAGGSGLSVVIGATIR
>NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein
MERFWFLFAIGSLAFLIYRYNQICRKNPGLNRQVYAFTLALFLIVFIVANIYEYICAAPLFVIYLIFLLKTFFDHDKILALSALITVVASFNLMLENISVFSSFFLLAWLAFIFTVFHRKDSANSKALDGSGRRNSSDSENDRNVRLPVKAERRELELIRKTRGDLENRRFLALRVRSMRL
>NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein
MTSEVPTEVIQQFHALCQRQDFKSALPLARHLRPMLIRDRRLANTWGWVLYRQLKNLQQRLQQKDGRAANNLPEHLAQQVREILVEYARLPNLHRPDLLHALMLATVCRIGTRWRGILGFLYYVRAFDTLRPEDRRPRTLQQRTYPSLEQQLTRTVAAALAKLPLEDQRPEVLNWASTQVQQRLSRFPDEPWIPYHLACYLIKKQRISEARPLLAPVLLQHHQKSWIWEKVARANQDRPAHRLTALTQALRLATKEHPVVRFRLHLYLAELLAAEQRYDEAAAQLQAARRLEKELGRNEQDRRNPLWRSYRQMLQQPWFRQRAERTDLPQEPALTIQPDVILYEHQPLQEAFGVVIHHNPDRNRTLIRLSPSEVVSVKHRRFPQASRLEPGTVVWLCLAEKRVVALEPRAGHPLPDLVRRFRGRLLQPEGRAFAFVLTEDNERIFIAPGLNRQLALEAGAMVEVLAERTIDPKKKMLSWSALKVEPVADR
>NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase
MEKLSNEQQRVLDHVLAWLERNDAPPIFILTGSAGTGKTLLIRHLVRALQDRRIHYALAAPTGRAARILSERTGDHARTLHSLIYIFDRYQLVEEADRQTDEPLSLQLHFALRSAEHDARLIIVDEASMVSDTAGEEELYRFGSGRLLNDLLTFARLIPKRDRPPITRLLFVGDPAQLPPVGQSVSPALSAQYLRDTFGLSAETAHLRSVYRQRKGHPILEAATALRNALEKGHYHTFRLPEQPPDLRPVGLEEAIETTATDFRRQNPSVLLCRTNALARKLNAAVRARLWGREGLPPQPGDLLLVNRNAPLHGLFNGDLVLVETVGPLEHRRVGRRGRPPVDLYFRDVELLYPHEKPRNRIRCKLLENLLESPDGQLSPDIIQALLIDFYRRHPSLKHGSSEFRLMLANDAYFNALHVRYGYAMTVHKAQGGEWKRATVVFNDWRHFRHAEFFRWAYTAITRAREELLTIGAPSFEALSDMRWQPAPSVPAPEQAAENATRFPLKALEAYHQRLSEALTAAGIETTGVELLQYAVRYHLARADRTTRIQYYYRGDGQISRIVTLGGADDPELTQQAYALFERILSEPPADSGELPENPLLREFLERAHLRLEGSGIRIVHWKEMPYALRLYFSADGENVTIDFYYNRRGVWTHAQEVGRSSSGALFARIQSLLQADS
>NC_015970.1|WP_014072552.1|74875_75145_-|hypothetical-protein
MNDFWYDGDFEFGDEFEGDFESDDYEGFQDLPDHRDWEEDWDEEWDDWDDELDDGRATCDFCGAPVGRYGYDDGYLTLCEDCRDQMYGD
>NC_015970.1|WP_014072551.1|74499_74868_-|single-stranded-DNA-binding-protein
MEPIKPGRTVNRVILLGRLAEPPTPVPGAGEACQMILTTEERGRNAAGEPIMRLERHLLLIEEPGLTAFCLQHLQVGMTLYVEGSLRRNENPATDSIPVAVWVRRLMVASWDPGGLPDDPPV
>NC_015970.1|WP_014072550.1|73900_74221_-|hypothetical-protein
MRTSYRFTLHYRGRNPALMPALIRSLSQMGYGPVTGPVFTWTFEQPRLDEVLKKLQHRICRELARSGAPGEEVTVTYGPAAIAAGYVELFGEELSPDMEDWPELSR
>NC_015970.1|WP_014072549.1|73465_73840_-|hypothetical-protein
MACPVLLEFEIYIEGESDLEKDLEGLRQRLPEAEVKAYPRVFDLEVSCLVEVEAERIYDEVDRICETIKDWASSHLNGRRPCASIKWDVPRMLKGRMRVRYEEAREFMSRRREHICAQVQQHCN
>NC_015970.1|WP_014072548.1|70871_72470_-|CRISPR-associated-endonuclease-Cas1
MEAGQIYDAEVPEGPCWPVAWVYEFAYCLRRGYYAWVEGPGEPVALDTGEGVWLASDAWGGPVRWVQDGAGCPVPLLRVPRACADDSDRRPEHLMLAALADLVEAHTGQPVRRGLVLDATTGRREEITLDETLRAAWQSLDRRIRAVIHEGSVPPPRADGRCHHCPRLEVCRPFFGHAEEAAVAIMPPVRQARTLYVDEIGAVVRRKGRQLVVTVSRDGRRQELLRVPALLVDQVVLVGPVQITSQALRMLLRRNVDIVYLSGEGRFEGRLAAEFHPHVALRLAQYEAFRDPERTLTLARLFVRGKLQNMAGLLRRYADEYGSASLRAAASEINRDLERLEQVTTLEALRGVEGTASRRYFSVFGEMLRAEAHAPTGWPAFPGRNRRPPTDPVNATLGYLYALLLGNVVAACALAGLDPYVGYLHAPAYGRPSLALDLMEEFRAPAADRLALRLFNRGRLRPQHFEERNGGVYLNEAGRAVVLEAWQAHRQQTSAHPVLGMELSLARHFEAQARLLARALQEQGIAYTPFVA
>NC_015970.1|WP_014072547.1|70589_70871_-|CRISPR-associated-endonuclease-Cas2
MAFWLVGYDIAEPRRLQRVARLLEDYGQRLHYSVFLCRLEAGEMRRLRQGLLHIVDLEEDRLFFLRLCRGCIDALEQMGQGRGIDPRQDHWIV
>NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein
MRVRFLLVRLPFQQSMVLVMKELEGEQRVAIVPVVAPGETFHEEQAYRIFQEVAAGRLPAGAEELGEFEFPDEEAAQEAARDFVKNLKESLWGEVEAFGEKQQPSSVDTVLLLTVGGSTEPLVHAIRNLDLARSRVLFICSPDSRTLVEGGEGIMQRLPDMAGLERSRYDVMVWKDPDDLAGCVAALFELYRQIRREYPGARIAANYTGGTKTMSAALVIGAVLLGWELQLNVGVRQDLRQVLAGTDVPTRVAADDVLLRLELRLVRQALDRYDYGAAEGLVQEWLRTLSLGGERRTQVLLLYQIVRGLAAWDLGQYRQALVSFGLAGEHGASWLPRLRVLAEGQEDTFELVADLLLGAARRAHQRRYDDAVVRLLRALELFGTIRLRQAHGLDVGQLEPARLPERLRETLASTGYRGAVEVETVYRLLEALGDPVGRLFAKRRTSLLEALEQSRHSRLIGGNFSIDEQTYGVVRSRLEGFLHEAARLTDQTLQAPQLPRSEVLDWVGLE
>NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein
MRRLGIILRQIAARGRPNRIKNCRNPENRGWLRTPMGGGGSGMHFYLWWAQSDSERVAPLAPTENEVFLRTIRHHDEHTPLDCGHRDDYIHLSLQELQTERIDGVDCSPWTPEQRAFIEAGEAVRIILGRPGSGKTASLWRAVERHPARHLLYLTWSRELAWQAHLNFSALTPDRTIRCWHFTRLLRALTQQDEPRLTLSESRRRFREAL
>NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein
MSAPQLGPWKHRLTALHAELRAFLIGRARPGHTSTVFDGRVFHLRPEAYAGLRQNDRHPEAIEKAWHVFELLGRDERLAEIFPELALASLAIRTLQAGRLPAVLDTIEGIVVDEVQDLTLLELSVVVELWRRLAQRRPEPPLLLLAGDEGQTVRPSGFRWGPYKDWLSERIAPPRDYELGESLRCPANIVRTFDRAARYYRKLPREERPARQRRDSPAAPGGHLIYVATENQQQAASLIHELCEEEALVVVSLEDEVPEHIWSPALIKGLERQTVVVLNPGAVLERLDRFVSEENFAFDREDYRTEVDRLRVALSRSSETLVFLDVAPTAAQRACSLRLLGDDAVEVAPHELLNSLEQAELSLLERIQARLEEFTARIDEDPSQALQLALRARELQLRIQSLGEHIPARIAREVSRAILSATARLLVDDHPTEVDAPELQQAREAARELGLEHLRALDELVRWHRSGRTFPAALLQAACQLPDEAEWLRQALSAIAYSLHAALEHGARSPESAAVFLEDVASWLRFLDYGGNVEEAVRRLRGLAFDALLAAGNLATAEQLLEHIHPPDLLRKGRLLEARDALEEAIEVYLQAGAHTEAERVRQRLYHFRNHTLQRFRRLADQCSDPEQIPVLISMLSGAQQRLAFWYIRLCLETKHGSDDQSPLHPFLGYLEAVHAHAELLEDPELMMLGALEELSRRRHRACGAATRLLFERFGTRSMARRLLASPIGELPECSEPAVFCLAASVLETLRNCPPYQKLLAFSDHGKPTRGPAES
>NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein
MSRLRDATLLLTEAQQGVDQVLRGCQHLNDRVADLFEHLHAAANALQEAGFPELKERLDQQKTDLEKLQERQQEALRQFDALRKTLEYLHQSILRLAAGYNSLQLRLQATGEQLQTGFESLMLATSRLTDRIAAIETRQQRSLWTLAAVAGLVLLTLIVVLWP
>NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein
MNEGDRILEAERQIRQLAEELDRLFRAANLLKSAQEQLDEVAQSSRRLVEETGKFITTAGDIVARLSEADLPRQIEAITQQVREAHERLLATLQEHVAALQSLEEEESGRLRERLENLERLQEDRFEQLRDLLGAIQKGQHEGVSALREAIQQNTTAIRSLMEEESGRLRETLKALQTRVTLVLATLGVIILLLLLLIFRAG
>NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase
MDRYWYSAAARLGLWDTLPEAQQGLVNNLYRRLRFYAHAVLEGYEAFAFDKTESESLSSLLAVIDKLTIRGCPTLVDLDLETALLEGPCRQFVDAVPIEDGPVVGWKFRRFLLPVQFSDLIRATVELLELPFSSNGKDGTDDLAYPVITPELEALSSEEEHLFIEQFANVFGSHLLRKLRRQVPLQDLVPYELEEPFVRQRVDFALQIGRLRYVFEIDGRQHLEPGQRRLDDQRDQLLKNAGWQVIRIPVEVVRQGRGSQLQTLHDRLREAQLEGLEQIGRTSVLDLVASSDLYRAALYGWIYPLAVHRCLRGLAFLYRFGYLDAGRPQRVLVIEEDIPVVASAFRILHTYWDHLRALAPEVPPPPTLEVDVIGCDEIEILAPVEGTRRVTAPSGSYDLVLDHSFWLYDGSEGPLEKELQPLPPGRYVRLRRAFGLREERSLTWSAALHYDLGDLERALIAEAEGRPAEMPERKVAALRFFLQQIFRKRDFWEGQLRVIARLLQGRPTVVLLPTGGGKSLTYQYSGMLLPGMTIVVDPLISLMIDQVDNLRGFAIDMVASISSIIDTEARERIIAQMGAGKLAYVFISPERLQSDDFRQKLQDVAARLPISLAVVDEAHCVSEWGHDFRPSYLHMTHNLQKFCASAASRPTLVALTGTASFAVLTDIQAELGITDESAIVLPRSFDRKEIRFHVERVPREAKMHALKRFRSQLPYLLRVNPQRFFELSGAETNCGIVFCPHVNGELGVWEVALELGHGKCYAGKQPRSFNEQRHGKWPDFKLKVQKDFKHNRIQEIVATKSFGMGIDKPNIRYTIHICIPHSVEAFYQEAGRAGRNGKPGYAISAILYSDENWVEAMGIFNEADHRKAQKKIENIPWNSRGDLLIQLWLLYNTYRGRDDEYQRALDFWKRYVRPELKELPVGATRLLEIPFTQSRRVDDEEEETNRGALEKSIFRMVILRIVEDYTIDWNQSIFQLRVRNAAPIEIKQSLRNYLGRYKLPATADQMVQPIPEDDQEKALEAALEVLIDFVYGEIAAKRKQALRTMAELCRNFRSDRDFREAILAYLQESEFSAELRTWIGRGFDEIGLEKIRDLLGKLSSLDEIKRLVGTTRRMLDEDPGNVPLRYLSAVARALSRVESEESVLEEVVSLTLQILRLKDRLRDPDEILAALLGDLATARPELLARAADRVLRLFGTPALARRLLQGPAGSDAVVRNHAAVLLMAESLRTIRESAFYQTLVNAV
>NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease
MHLRRKREPDVVEEAIIQQKAASLHPLLGWIVCISVQRAVDNPFQPNPPHSYLAPTPDDERDMLERFWHDVQQFVDRRERICWITFNGKRFDVPFLLARTLHHGLAPVQCDLLDTYPYNQYPHCDLSKLFEGINLGLADLCALLNVSNPKEYGDGNQVQHMLETEGIEAVRRYCEADVEATMQCFARLLPLLPPACQPRG
>NC_015970.1|WP_014072560.1|93544_94675_-|transposase
MRTTFKYRLYRSKRDKHLIEQIEVAASIWNHSVALTRRYYRIYGKYPGANRLMKHIARLRRRNPYWQKLGSQAVQDVIQRLDRAYWRFFSDPKAGRPRFKKRERYSSFTLKQAGWKYPGGNRIRIGKHNYKFVLSRPIQGEIKTVTIKRDRVGRLWICFSVVTEEQPKPPAPHEAVMRPVGLDFGLKCFLTLSDGTKIQSPEFFRRGLQEVRKAHRALSRKQRGSNNYRKARVRLAKVYDRISNQRRDWFFKTAHALCERYDFIALEDLNIEGMKRRWGRKVSDLGFGEFVSILEHVARKRGVRVAKVARFFPSSRRCSCCGWVKENLSLADREWTCERCGTVHDRDENAAINICREGASSLGVGDVRPPEAAVAV
>NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein
MLKNKRPDSLWKDMLSLLNTLGEEELDILAQLIIALLTARKKFSLAEEPESDADAAKSPAGSASSRQKKKRVTIRVEYRKCGKDCRCNGGRGHGPYRYMYWVENGRLRSRYLGRA
>NC_015970.1|WP_014072561.1|95831_96767_+|hypothetical-protein
MKRSDVYQDERYIAMNPFVALQPQDVGETRIVRTWTDTNGFKHEFIIEAPRIAGEYAEQVFIALLYFTYQQRKKGHDLPSCVTVNQSDLFNIMHWPSTGRYSSRLKDSLDYYMSVKITTNTYRQRRELRILSTHVLAGYEIYTQGRRKRVRWEWAPDFLAQIQEGDHLYSNVNDYFSLSTPTSRRCFRLLQALTIPGGKPYVADLKHFAEIRMGMGSTRVFAHVARRLENALEELRAKKLGIGFITENPERIILARYPKDSAETLSIFAELPDRIKNQLPPPRLPGLAGQYEQREQVSRLILEIPVILKDG

Crispr_ID: NC_015970_8

• CRISPR_ID: NC_015970_8
• CRISPR_location: 91071-92220
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 14 spacers
• Cas_protein_info: csx1,cas14j

Consensus repeat of NC_015970_8

Consensus_repeat	Method
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CRT

spacers of NC_015970_8

>8.1|91108|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT
AAGAACTGGCTCATCGAGATCGGCGGGCAGGCTTATGGTCTGTA
>8.2|91189|40|NC_015970|PILER-CR,CRISPRCasFinder,CRT
TATTCCTAACCTGAACAGCGACGTCATAACCGACGAGCCC
>8.3|91266|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT
TACATCACGATTCGAGATCGCACGCGGCGAGTACTTTCTCG
>8.4|91344|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT
GGCAAAGAGACTGTATGCCAGGCGGACGTCACCCCAGCGCTTCGACG
>8.5|91428|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT
GGGATGAGCAGTCGGCGGTGTCCATCGTGCTGTTCATGTACGG
>8.6|91508|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT
GGCGAACGGGATCGTGACGTGCTTTAACGTGTTTGTGTGAAGAAAA
>8.7|91591|39|NC_015970|PILER-CR,CRISPRCasFinder,CRT
GGCATCAAGCGGGTTCTTACCCGTCTGCTTCGAGAGCGC
>8.8|91667|45|NC_015970|PILER-CR,CRISPRCasFinder,CRT
TGGCGCGCTTCAGGGCGGGCAAGTTTGTAATCTTAAGTATTCAGA
>8.9|91749|45|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CCAAATCGACAAGGACGGCAACATCGTCGTCGGCGGCCGGGTCAT
>8.10|91831|36|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CAAAACTACGGTGGGAGCCATGAAGAAGATCAAAGA
>8.11|91904|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT
TTGCGTCGTCCCTGCGGGCGGCGCAACGAGTCGCGGAGCGGGAGTG
>8.12|91987|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT
ATGAAGAAGGTAACGAGCGGGAATTTGTAGACGTGGCAAAGGAT
>8.13|92068|37|NC_015970|PILER-CR,CRISPRCasFinder,CRT
CTCAGGACGCCCCGTTCGGGTTTGCCTTCTACTGGCA
>8.14|92142|42|NC_015970|PILER-CR,CRISPRCasFinder,CRT
ACAATCAGTTCCGAGCCGTCGGGGAATATGCGTCGTACACTA

CRISPR arrays and Neighbor proteins around NC_015970_8

CRISPR arrays

The CRISPR arrays of NC_015970_8

>merge|NC_015970|8|91071-92220|PILER-CR,CRISPRCasFinder,CRT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACAAGAACTGGCTCATCGAGATCGGCGGGCAGGCTTATGGTCTGTAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTATTCCTAACCTGAACAGCGACGTCATAACCGACGAGCCCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTACATCACGATTCGAGATCGCACGCGGCGAGTACTTTCTCGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGCAAAGAGACTGTATGCCAGGCGGACGTCACCCCAGCGCTTCGACGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGGATGAGCAGTCGGCGGTGTCCATCGTGCTGTTCATGTACGGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGCGAACGGGATCGTGACGTGCTTTAACGTGTTTGTGTGAAGAAAAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACGGCATCAAGCGGGTTCTTACCCGTCTGCTTCGAGAGCGCGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTGGCGCGCTTCAGGGCGGGCAAGTTTGTAATCTTAAGTATTCAGAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCCAAATCGACAAGGACGGCAACATCGTCGTCGGCGGCCGGGTCATGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCAAAACTACGGTGGGAGCCATGAAGAAGATCAAAGAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACTTGCGTCGTCCCTGCGGGCGGCGCAACGAGTCGCGGAGCGGGAGTGGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACATGAAGAAGGTAACGAGCGGGAATTTGTAGACGTGGCAAAGGATGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACCTCAGGACGCCCCGTTCGGGTTTGCCTTCTACTGGCAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGACACAATCAGTTCCGAGCCGTCGGGGAATATGCGTCGTACACTAGTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|8|7|91071-92220|PILER-CR
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AAGAACTGGCTCATCGAGATCGGCGGGCAGGCTTATGGTCTGTA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TATTCCTAACCTGAACAGCGACGTCATAACCGACGAGCCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TACATCACGATTCGAGATCGCACGCGGCGAGTACTTTCTCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCAAAGAGACTGTATGCCAGGCGGACGTCACCCCAGCGCTTCGACG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGGATGAGCAGTCGGCGGTGTCCATCGTGCTGTTCATGTACGG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCGAACGGGATCGTGACGTGCTTTAACGTGTTTGTGTGAAGAAAA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCATCAAGCGGGTTCTTACCCGTCTGCTTCGAGAGCGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGCGCGCTTCAGGGCGGGCAAGTTTGTAATCTTAAGTATTCAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CCAAATCGACAAGGACGGCAACATCGTCGTCGGCGGCCGGGTCAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CAAAACTACGGTGGGAGCCATGAAGAAGATCAAAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TTGCGTCGTCCCTGCGGGCGGCGCAACGAGTCGCGGAGCGGGAGTG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	ATGAAGAAGGTAACGAGCGGGAATTTGTAGACGTGGCAAAGGAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CTCAGGACGCCCCGTTCGGGTTTGCCTTCTACTGGCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	ACAATCAGTTCCGAGCCGTCGGGGAATATGCGTCGTACACTA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|8|8|91071-92220|CRISPRCasFinder
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AAGAACTGGCTCATCGAGATCGGCGGGCAGGCTTATGGTCTGTA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TATTCCTAACCTGAACAGCGACGTCATAACCGACGAGCCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TACATCACGATTCGAGATCGCACGCGGCGAGTACTTTCTCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCAAAGAGACTGTATGCCAGGCGGACGTCACCCCAGCGCTTCGACG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGGATGAGCAGTCGGCGGTGTCCATCGTGCTGTTCATGTACGG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCGAACGGGATCGTGACGTGCTTTAACGTGTTTGTGTGAAGAAAA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCATCAAGCGGGTTCTTACCCGTCTGCTTCGAGAGCGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGCGCGCTTCAGGGCGGGCAAGTTTGTAATCTTAAGTATTCAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CCAAATCGACAAGGACGGCAACATCGTCGTCGGCGGCCGGGTCAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CAAAACTACGGTGGGAGCCATGAAGAAGATCAAAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TTGCGTCGTCCCTGCGGGCGGCGCAACGAGTCGCGGAGCGGGAGTG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	ATGAAGAAGGTAACGAGCGGGAATTTGTAGACGTGGCAAAGGAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CTCAGGACGCCCCGTTCGGGTTTGCCTTCTACTGGCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	ACAATCAGTTCCGAGCCGTCGGGGAATATGCGTCGTACACTA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

>NC_015970|8|5|91071-92220|CRT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	AAGAACTGGCTCATCGAGATCGGCGGGCAGGCTTATGGTCTGTA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TATTCCTAACCTGAACAGCGACGTCATAACCGACGAGCCC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TACATCACGATTCGAGATCGCACGCGGCGAGTACTTTCTCG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCAAAGAGACTGTATGCCAGGCGGACGTCACCCCAGCGCTTCGACG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGGATGAGCAGTCGGCGGTGTCCATCGTGCTGTTCATGTACGG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCGAACGGGATCGTGACGTGCTTTAACGTGTTTGTGTGAAGAAAA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	GGCATCAAGCGGGTTCTTACCCGTCTGCTTCGAGAGCGC
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TGGCGCGCTTCAGGGCGGGCAAGTTTGTAATCTTAAGTATTCAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CCAAATCGACAAGGACGGCAACATCGTCGTCGGCGGCCGGGTCAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CAAAACTACGGTGGGAGCCATGAAGAAGATCAAAGA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	TTGCGTCGTCCCTGCGGGCGGCGCAACGAGTCGCGGAGCGGGAGTG
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	ATGAAGAAGGTAACGAGCGGGAATTTGTAGACGTGGCAAAGGAT
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	CTCAGGACGCCCCGTTCGGGTTTGCCTTCTACTGGCA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC	ACAATCAGTTCCGAGCCGTCGGGGAATATGCGTCGTACACTA
GTCGTAATCCCCTTTTCATCGGGTCAAGTCTTCGGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072561.1|95831_96767_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072562.1|97141_97678_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845339.1|97769_98072_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|376852
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	unknown	unknown	gnl|CDD|214692
NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	gnl|CDD|274263
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	unknown	unknown	gnl|CDD|99825
NC_015970.1|WP_144295526.1|99007_99496_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	gnl|CDD|223747
NC_015970.1|WP_049772410.1|98699_98990_-|hypothetical-protein	unknown	unknown	gnl|CDD|227708
NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl|CDD|223588
NC_015970.1|WP_081472097.1|99875_100256_-|DUF4277-domain-containing-protein	unknown	unknown	gnl|CDD|379471
NC_015970.1|WP_012845340.1|98046_98475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350221
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|350691
NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	3.8e-74	245.2	0.0
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	1.2e-47	157.1	3.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_012845339.1|97769_98072_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.6281e-09
NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00733985
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	gnl|CDD|214692	smart00487, DEXDc, DEAD-like helicases superfamily.	0.000608512
NC_015970.1|WP_081472097.1|99875_100256_-|DUF4277-domain-containing-protein	gnl|CDD|379471	pfam14104, DUF4277, Domain of unknown function (DUF4277). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is approximately 110 amino acids in length. There is a conserved NGLGF sequence motif.	3.97875e-25
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	gnl|CDD|274263	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family. Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Archaea), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	8.28521e-39
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	gnl|CDD|99825	cd05782, DNA_polB_like1_exo, Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases. A subfamily of the 3'-5' exonuclease domain of family-B DNA polymerases. This subfamily is composed of uncharacterized bacterial family-B DNA polymerases. Family-B DNA polymerases contain an N-terminal DEDDy DnaQ-like exonuclease domain in the same polypeptide chain as the polymerase domain, similar to family-A DNA polymerases. This exonuclease domain contains three sequence motifs termed ExoI, ExoII and ExoIII, with a specific YX(3)D pattern at ExoIII. These motifs are involved in metal binding and catalysis. The exonuclease domain of family-B DNA polymerases has a fundamental role in proofreading activity. It contains a beta hairpin structure that plays an important role in active site switching in the event of a nucleotide misincorporation. Family-B DNA polymerases are predominantly involved in DNA replication and DNA repair.	1.73355e-25
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.96239e-48
NC_015970.1|WP_049772410.1|98699_98990_-|hypothetical-protein	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	7.35443e-05
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	gnl|CDD|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	3.89161e-83
NC_015970.1|WP_012845340.1|98046_98475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350221	cd09873, PIN_Pae0151-like, VapC-like PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Pyrobaculum aerophilum proteins, Pae0151 and Pae2754, and homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.80013e-31
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00313624
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00904018
NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase	gnl|CDD|350691	cd17933, DEXSc_RecD-like, DEXS-box helicase domain of RecD and similar proteins. RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.8702e-34

Protein sequences

>NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase
MDRYWYSAAARLGLWDTLPEAQQGLVNNLYRRLRFYAHAVLEGYEAFAFDKTESESLSSLLAVIDKLTIRGCPTLVDLDLETALLEGPCRQFVDAVPIEDGPVVGWKFRRFLLPVQFSDLIRATVELLELPFSSNGKDGTDDLAYPVITPELEALSSEEEHLFIEQFANVFGSHLLRKLRRQVPLQDLVPYELEEPFVRQRVDFALQIGRLRYVFEIDGRQHLEPGQRRLDDQRDQLLKNAGWQVIRIPVEVVRQGRGSQLQTLHDRLREAQLEGLEQIGRTSVLDLVASSDLYRAALYGWIYPLAVHRCLRGLAFLYRFGYLDAGRPQRVLVIEEDIPVVASAFRILHTYWDHLRALAPEVPPPPTLEVDVIGCDEIEILAPVEGTRRVTAPSGSYDLVLDHSFWLYDGSEGPLEKELQPLPPGRYVRLRRAFGLREERSLTWSAALHYDLGDLERALIAEAEGRPAEMPERKVAALRFFLQQIFRKRDFWEGQLRVIARLLQGRPTVVLLPTGGGKSLTYQYSGMLLPGMTIVVDPLISLMIDQVDNLRGFAIDMVASISSIIDTEARERIIAQMGAGKLAYVFISPERLQSDDFRQKLQDVAARLPISLAVVDEAHCVSEWGHDFRPSYLHMTHNLQKFCASAASRPTLVALTGTASFAVLTDIQAELGITDESAIVLPRSFDRKEIRFHVERVPREAKMHALKRFRSQLPYLLRVNPQRFFELSGAETNCGIVFCPHVNGELGVWEVALELGHGKCYAGKQPRSFNEQRHGKWPDFKLKVQKDFKHNRIQEIVATKSFGMGIDKPNIRYTIHICIPHSVEAFYQEAGRAGRNGKPGYAISAILYSDENWVEAMGIFNEADHRKAQKKIENIPWNSRGDLLIQLWLLYNTYRGRDDEYQRALDFWKRYVRPELKELPVGATRLLEIPFTQSRRVDDEEEETNRGALEKSIFRMVILRIVEDYTIDWNQSIFQLRVRNAAPIEIKQSLRNYLGRYKLPATADQMVQPIPEDDQEKALEAALEVLIDFVYGEIAAKRKQALRTMAELCRNFRSDRDFREAILAYLQESEFSAELRTWIGRGFDEIGLEKIRDLLGKLSSLDEIKRLVGTTRRMLDEDPGNVPLRYLSAVARALSRVESEESVLEEVVSLTLQILRLKDRLRDPDEILAALLGDLATARPELLARAADRVLRLFGTPALARRLLQGPAGSDAVVRNHAAVLLMAESLRTIRESAFYQTLVNAV
>NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein
MNEGDRILEAERQIRQLAEELDRLFRAANLLKSAQEQLDEVAQSSRRLVEETGKFITTAGDIVARLSEADLPRQIEAITQQVREAHERLLATLQEHVAALQSLEEEESGRLRERLENLERLQEDRFEQLRDLLGAIQKGQHEGVSALREAIQQNTTAIRSLMEEESGRLRETLKALQTRVTLVLATLGVIILLLLLLIFRAG
>NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein
MSRLRDATLLLTEAQQGVDQVLRGCQHLNDRVADLFEHLHAAANALQEAGFPELKERLDQQKTDLEKLQERQQEALRQFDALRKTLEYLHQSILRLAAGYNSLQLRLQATGEQLQTGFESLMLATSRLTDRIAAIETRQQRSLWTLAAVAGLVLLTLIVVLWP
>NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein
MSAPQLGPWKHRLTALHAELRAFLIGRARPGHTSTVFDGRVFHLRPEAYAGLRQNDRHPEAIEKAWHVFELLGRDERLAEIFPELALASLAIRTLQAGRLPAVLDTIEGIVVDEVQDLTLLELSVVVELWRRLAQRRPEPPLLLLAGDEGQTVRPSGFRWGPYKDWLSERIAPPRDYELGESLRCPANIVRTFDRAARYYRKLPREERPARQRRDSPAAPGGHLIYVATENQQQAASLIHELCEEEALVVVSLEDEVPEHIWSPALIKGLERQTVVVLNPGAVLERLDRFVSEENFAFDREDYRTEVDRLRVALSRSSETLVFLDVAPTAAQRACSLRLLGDDAVEVAPHELLNSLEQAELSLLERIQARLEEFTARIDEDPSQALQLALRARELQLRIQSLGEHIPARIAREVSRAILSATARLLVDDHPTEVDAPELQQAREAARELGLEHLRALDELVRWHRSGRTFPAALLQAACQLPDEAEWLRQALSAIAYSLHAALEHGARSPESAAVFLEDVASWLRFLDYGGNVEEAVRRLRGLAFDALLAAGNLATAEQLLEHIHPPDLLRKGRLLEARDALEEAIEVYLQAGAHTEAERVRQRLYHFRNHTLQRFRRLADQCSDPEQIPVLISMLSGAQQRLAFWYIRLCLETKHGSDDQSPLHPFLGYLEAVHAHAELLEDPELMMLGALEELSRRRHRACGAATRLLFERFGTRSMARRLLASPIGELPECSEPAVFCLAASVLETLRNCPPYQKLLAFSDHGKPTRGPAES
>NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein
MRRLGIILRQIAARGRPNRIKNCRNPENRGWLRTPMGGGGSGMHFYLWWAQSDSERVAPLAPTENEVFLRTIRHHDEHTPLDCGHRDDYIHLSLQELQTERIDGVDCSPWTPEQRAFIEAGEAVRIILGRPGSGKTASLWRAVERHPARHLLYLTWSRELAWQAHLNFSALTPDRTIRCWHFTRLLRALTQQDEPRLTLSESRRRFREAL
>NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein
MRVRFLLVRLPFQQSMVLVMKELEGEQRVAIVPVVAPGETFHEEQAYRIFQEVAAGRLPAGAEELGEFEFPDEEAAQEAARDFVKNLKESLWGEVEAFGEKQQPSSVDTVLLLTVGGSTEPLVHAIRNLDLARSRVLFICSPDSRTLVEGGEGIMQRLPDMAGLERSRYDVMVWKDPDDLAGCVAALFELYRQIRREYPGARIAANYTGGTKTMSAALVIGAVLLGWELQLNVGVRQDLRQVLAGTDVPTRVAADDVLLRLELRLVRQALDRYDYGAAEGLVQEWLRTLSLGGERRTQVLLLYQIVRGLAAWDLGQYRQALVSFGLAGEHGASWLPRLRVLAEGQEDTFELVADLLLGAARRAHQRRYDDAVVRLLRALELFGTIRLRQAHGLDVGQLEPARLPERLRETLASTGYRGAVEVETVYRLLEALGDPVGRLFAKRRTSLLEALEQSRHSRLIGGNFSIDEQTYGVVRSRLEGFLHEAARLTDQTLQAPQLPRSEVLDWVGLE
>NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein
MRRIALLFGLLLALPLRAQPTFDLLGGLGPARLGAGQNRSAMHGWFAAGGHLPSGVGGFLVVDLLQATAPEQSGIIWEGGYALSGVATVVAYRMTSRRLLFGTLAGPGLWQLSIDASVSGVNTAVKDHTAIGFLLGGYGLVRLGGTFTAGLLFTRRWTATEPSSVGCFVECLSRTIGNGHAGGSGLSVVIGATIR
>NC_015970.1|WP_012845328.1|79089_79635_-|hypothetical-protein
MERFWFLFAIGSLAFLIYRYNQICRKNPGLNRQVYAFTLALFLIVFIVANIYEYICAAPLFVIYLIFLLKTFFDHDKILALSALITVVASFNLMLENISVFSSFFLLAWLAFIFTVFHRKDSANSKALDGSGRRNSSDSENDRNVRLPVKAERRELELIRKTRGDLENRRFLALRVRSMRL
>NC_015970.1|WP_014072554.1|77386_78859_+|hypothetical-protein
MTSEVPTEVIQQFHALCQRQDFKSALPLARHLRPMLIRDRRLANTWGWVLYRQLKNLQQRLQQKDGRAANNLPEHLAQQVREILVEYARLPNLHRPDLLHALMLATVCRIGTRWRGILGFLYYVRAFDTLRPEDRRPRTLQQRTYPSLEQQLTRTVAAALAKLPLEDQRPEVLNWASTQVQQRLSRFPDEPWIPYHLACYLIKKQRISEARPLLAPVLLQHHQKSWIWEKVARANQDRPAHRLTALTQALRLATKEHPVVRFRLHLYLAELLAAEQRYDEAAAQLQAARRLEKELGRNEQDRRNPLWRSYRQMLQQPWFRQRAERTDLPQEPALTIQPDVILYEHQPLQEAFGVVIHHNPDRNRTLIRLSPSEVVSVKHRRFPQASRLEPGTVVWLCLAEKRVVALEPRAGHPLPDLVRRFRGRLLQPEGRAFAFVLTEDNERIFIAPGLNRQLALEAGAMVEVLAERTIDPKKKMLSWSALKVEPVADR
>NC_015970.1|WP_014072553.1|75332_77369_+|AAA-family-ATPase
MEKLSNEQQRVLDHVLAWLERNDAPPIFILTGSAGTGKTLLIRHLVRALQDRRIHYALAAPTGRAARILSERTGDHARTLHSLIYIFDRYQLVEEADRQTDEPLSLQLHFALRSAEHDARLIIVDEASMVSDTAGEEELYRFGSGRLLNDLLTFARLIPKRDRPPITRLLFVGDPAQLPPVGQSVSPALSAQYLRDTFGLSAETAHLRSVYRQRKGHPILEAATALRNALEKGHYHTFRLPEQPPDLRPVGLEEAIETTATDFRRQNPSVLLCRTNALARKLNAAVRARLWGREGLPPQPGDLLLVNRNAPLHGLFNGDLVLVETVGPLEHRRVGRRGRPPVDLYFRDVELLYPHEKPRNRIRCKLLENLLESPDGQLSPDIIQALLIDFYRRHPSLKHGSSEFRLMLANDAYFNALHVRYGYAMTVHKAQGGEWKRATVVFNDWRHFRHAEFFRWAYTAITRAREELLTIGAPSFEALSDMRWQPAPSVPAPEQAAENATRFPLKALEAYHQRLSEALTAAGIETTGVELLQYAVRYHLARADRTTRIQYYYRGDGQISRIVTLGGADDPELTQQAYALFERILSEPPADSGELPENPLLREFLERAHLRLEGSGIRIVHWKEMPYALRLYFSADGENVTIDFYYNRRGVWTHAQEVGRSSSGALFARIQSLLQADS
>NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease
MHLRRKREPDVVEEAIIQQKAASLHPLLGWIVCISVQRAVDNPFQPNPPHSYLAPTPDDERDMLERFWHDVQQFVDRRERICWITFNGKRFDVPFLLARTLHHGLAPVQCDLLDTYPYNQYPHCDLSKLFEGINLGLADLCALLNVSNPKEYGDGNQVQHMLETEGIEAVRRYCEADVEATMQCFARLLPLLPPACQPRG
>NC_015970.1|WP_014072560.1|93544_94675_-|transposase
MRTTFKYRLYRSKRDKHLIEQIEVAASIWNHSVALTRRYYRIYGKYPGANRLMKHIARLRRRNPYWQKLGSQAVQDVIQRLDRAYWRFFSDPKAGRPRFKKRERYSSFTLKQAGWKYPGGNRIRIGKHNYKFVLSRPIQGEIKTVTIKRDRVGRLWICFSVVTEEQPKPPAPHEAVMRPVGLDFGLKCFLTLSDGTKIQSPEFFRRGLQEVRKAHRALSRKQRGSNNYRKARVRLAKVYDRISNQRRDWFFKTAHALCERYDFIALEDLNIEGMKRRWGRKVSDLGFGEFVSILEHVARKRGVRVAKVARFFPSSRRCSCCGWVKENLSLADREWTCERCGTVHDRDENAAINICREGASSLGVGDVRPPEAAVAV
>NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein
MLKNKRPDSLWKDMLSLLNTLGEEELDILAQLIIALLTARKKFSLAEEPESDADAAKSPAGSASSRQKKKRVTIRVEYRKCGKDCRCNGGRGHGPYRYMYWVENGRLRSRYLGRA
>NC_015970.1|WP_014072561.1|95831_96767_+|hypothetical-protein
MKRSDVYQDERYIAMNPFVALQPQDVGETRIVRTWTDTNGFKHEFIIEAPRIAGEYAEQVFIALLYFTYQQRKKGHDLPSCVTVNQSDLFNIMHWPSTGRYSSRLKDSLDYYMSVKITTNTYRQRRELRILSTHVLAGYEIYTQGRRKRVRWEWAPDFLAQIQEGDHLYSNVNDYFSLSTPTSRRCFRLLQALTIPGGKPYVADLKHFAEIRMGMGSTRVFAHVARRLENALEELRAKKLGIGFITENPERIILARYPKDSAETLSIFAELPDRIKNQLPPPRLPGLAGQYEQREQVSRLILEIPVILKDG
>NC_015970.1|WP_014072562.1|97141_97678_+|hypothetical-protein
MQTLTLRTRLDPTPEQVDALQETLERFAQACNLTLEVARACRTFRKFKLQRLVYGQLRALGLSANLAIRAIARVDHRAKHFRPTSCDYDQRTLSLRGEHVSLSTTRGRLRIPMRLSPYHRYWLARARSVQGGRLLRDRRGRWYVHLIVRVPGDRAARSRITRPGSRTTARAAPQASSR
>NC_015970.1|WP_012845339.1|97769_98072_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MKRIVSATEARVHLGAIMREIVEKGEHVVVERGGRPYVVMLSVEEYEHLCKKPDRGVWRALVLRARERVREDVGDRPIPPPEEIIRTSREERDAGFLDLH
>NC_015970.1|WP_012845340.1|98046_98475_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MPGSWICIDASIVVRLVARPDDHVVLERWDAWLAEGRRLAAPTLLFYEVTNALHRYHRHGWMKEGTVRSALEAALALPVELHGDASLHERALEMATELGLAAAYDAHYLALAERLRAEFWTADGKLVRAVGARFDWVRLLGS
>NC_015970.1|WP_049772410.1|98699_98990_-|hypothetical-protein
MALLMVMGWALPVYALAEHRLRSVLRKRGESIPNQFGKPTQRPTMRRIFQMFEGIDVLLLPTLDGVQQQVLNLEAVHCQILRLLGPCVGKCCQDTS
>NC_015970.1|WP_144295526.1|99007_99496_-|hypothetical-protein
MRQRWLVVWSAQAEQREQAVLHKRVEKERQAAENAWRRRCRRAFASQEEAEATVEAQAKHYRCHRVEVHYRPVLHDEERGRPPAGAMPCRVGVCLEGALVAKAEAIAAARKRLGTFILATNELDERALPTEEMLWAYKGQGWDRSEVSAFSKTPGSLPIACF
>NC_015970.1|WP_081472097.1|99875_100256_-|DUF4277-domain-containing-protein
MTDLTTHIPHFGKQEMRFCGILQKQEDTNDQEIRNATSGSPGHRSRYLPGDWPGRVKGPPARARPTSVGEAVQAMVLKAPGFTGRPLYLTPEFFANKPLDRLLRPGLTAEILHDDSLGRALDMLHE

Crispr_ID: NC_015970_9

• CRISPR_ID: NC_015970_9
• CRISPR_location: 95340-95500
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas14j,csx1

Consensus repeat of NC_015970_9

Consensus_repeat	Method
AATTCGTACAGTTGATCCGCAAAA	PILER-CR

spacers of NC_015970_9

>9.1|95364|38|NC_015970|PILER-CR
CCGCTTTATTTTGACTCGAAATGCACAATTATGACCTG
>9.2|95426|57|NC_015970|PILER-CR
GAGGCATCTCCACCCCACCCGCGAAAATCGGCCAATTTCGCCGATTCCGGATCGGTC

CRISPR arrays and Neighbor proteins around NC_015970_9

CRISPR arrays

The CRISPR arrays of NC_015970_9

>merge|NC_015970|9|95340-95500|PILER-CR
ATTCGTACAGTTGATCCGCAAAACCGCTTTATTTTGACTCGAAATGCACAATTATGACCTGACTTCGTACACTTGATCCGGAGGCATCTCCACCCCACCCGCGAAAATCGGCCAATTTCGCCGATTCCGGATCGGTCAATTCGTACAGTTGATCCGTAAAA

>NC_015970|9|8|95340-95500|PILER-CR
ATTCGTACAGTTGATCCGCAAAAC	CGCTTTATTTTGACTCGAAATGCACAATTATGACCTGA
CTTCGTACACTTGATCCGGAGGCA	TCTCCACCCCACCCGCGAAAATCGGCCAATTTCGCCGATTCCGGATCGGTCAATTCG
TACAGTTGATCCGTAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015970.1|WP_014072561.1|95831_96767_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845341.1|100461_100665_-|HEPN-domain-containing-protein	unknown	unknown	gnl|CDD|368314
NC_015970.1|WP_012845339.1|97769_98072_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl|CDD|376852
NC_015970.1|WP_144295526.1|99007_99496_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	unknown	unknown	gnl|CDD|214692
NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	gnl|CDD|274263
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	unknown	unknown	gnl|CDD|99825
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	gnl|CDD|223747
NC_015970.1|WP_049772410.1|98699_98990_-|hypothetical-protein	unknown	unknown	gnl|CDD|227708
NC_015970.1|WP_027614307.1|101641_101968_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl|CDD|223588
NC_015970.1|WP_081472097.1|99875_100256_-|DUF4277-domain-containing-protein	unknown	unknown	gnl|CDD|379471
NC_015970.1|WP_012845340.1|98046_98475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl|CDD|350221
NC_015970.1|WP_014072563.1|100813_101650_+|IS982-family-transposase	unknown	unknown	gnl|CDD|372648
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_015970.1|WP_014072562.1|97141_97678_+|hypothetical-protein	unknown	unknown	unknown
NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	cas14j	-	3.8e-74	245.2	0.0
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	1.2e-47	157.1	3.8

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015970.1|WP_012845341.1|100461_100665_-|HEPN-domain-containing-protein	gnl|CDD|368314	pfam05168, HEPN, HEPN domain.	3.36234e-08
NC_015970.1|WP_012845339.1|97769_98072_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl|CDD|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.6281e-09
NC_015970.1|WP_049772410.1|98699_98990_-|hypothetical-protein	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	7.35443e-05
NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00313624
NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein	gnl|CDD|274263	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family. Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Archaea), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	8.28521e-39
NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease	gnl|CDD|99825	cd05782, DNA_polB_like1_exo, Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases. A subfamily of the 3'-5' exonuclease domain of family-B DNA polymerases. This subfamily is composed of uncharacterized bacterial family-B DNA polymerases. Family-B DNA polymerases contain an N-terminal DEDDy DnaQ-like exonuclease domain in the same polypeptide chain as the polymerase domain, similar to family-A DNA polymerases. This exonuclease domain contains three sequence motifs termed ExoI, ExoII and ExoIII, with a specific YX(3)D pattern at ExoIII. These motifs are involved in metal binding and catalysis. The exonuclease domain of family-B DNA polymerases has a fundamental role in proofreading activity. It contains a beta hairpin structure that plays an important role in active site switching in the event of a nucleotide misincorporation. Family-B DNA polymerases are predominantly involved in DNA replication and DNA repair.	1.73355e-25
NC_015970.1|WP_014072560.1|93544_94675_-|transposase	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.96239e-48
NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein	gnl|CDD|214692	smart00487, DEXDc, DEAD-like helicases superfamily.	0.000608512
NC_015970.1|WP_027614307.1|101641_101968_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	1.93491e-11
NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase	gnl|CDD|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	3.89161e-83
NC_015970.1|WP_012845340.1|98046_98475_+|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl|CDD|350221	cd09873, PIN_Pae0151-like, VapC-like PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Pyrobaculum aerophilum proteins, Pae0151 and Pae2754, and homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.80013e-31
NC_015970.1|WP_014072563.1|100813_101650_+|IS982-family-transposase	gnl|CDD|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	6.60729e-12
NC_015970.1|WP_081472097.1|99875_100256_-|DUF4277-domain-containing-protein	gnl|CDD|379471	pfam14104, DUF4277, Domain of unknown function (DUF4277). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is approximately 110 amino acids in length. There is a conserved NGLGF sequence motif.	3.97875e-25
NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00904018

Protein sequences

>NC_015970.1|WP_012845336.1|94960_95308_+|hypothetical-protein
MLKNKRPDSLWKDMLSLLNTLGEEELDILAQLIIALLTARKKFSLAEEPESDADAAKSPAGSASSRQKKKRVTIRVEYRKCGKDCRCNGGRGHGPYRYMYWVENGRLRSRYLGRA
>NC_015970.1|WP_014072560.1|93544_94675_-|transposase
MRTTFKYRLYRSKRDKHLIEQIEVAASIWNHSVALTRRYYRIYGKYPGANRLMKHIARLRRRNPYWQKLGSQAVQDVIQRLDRAYWRFFSDPKAGRPRFKKRERYSSFTLKQAGWKYPGGNRIRIGKHNYKFVLSRPIQGEIKTVTIKRDRVGRLWICFSVVTEEQPKPPAPHEAVMRPVGLDFGLKCFLTLSDGTKIQSPEFFRRGLQEVRKAHRALSRKQRGSNNYRKARVRLAKVYDRISNQRRDWFFKTAHALCERYDFIALEDLNIEGMKRRWGRKVSDLGFGEFVSILEHVARKRGVRVAKVARFFPSSRRCSCCGWVKENLSLADREWTCERCGTVHDRDENAAINICREGASSLGVGDVRPPEAAVAV
>NC_015970.1|WP_012845334.1|92695_93298_-|exonuclease
MHLRRKREPDVVEEAIIQQKAASLHPLLGWIVCISVQRAVDNPFQPNPPHSYLAPTPDDERDMLERFWHDVQQFVDRRERICWITFNGKRFDVPFLLARTLHHGLAPVQCDLLDTYPYNQYPHCDLSKLFEGINLGLADLCALLNVSNPKEYGDGNQVQHMLETEGIEAVRRYCEADVEATMQCFARLLPLLPPACQPRG
>NC_015970.1|WP_014072559.1|87132_90864_-|RecQ-family-ATP-dependent-DNA-helicase
MDRYWYSAAARLGLWDTLPEAQQGLVNNLYRRLRFYAHAVLEGYEAFAFDKTESESLSSLLAVIDKLTIRGCPTLVDLDLETALLEGPCRQFVDAVPIEDGPVVGWKFRRFLLPVQFSDLIRATVELLELPFSSNGKDGTDDLAYPVITPELEALSSEEEHLFIEQFANVFGSHLLRKLRRQVPLQDLVPYELEEPFVRQRVDFALQIGRLRYVFEIDGRQHLEPGQRRLDDQRDQLLKNAGWQVIRIPVEVVRQGRGSQLQTLHDRLREAQLEGLEQIGRTSVLDLVASSDLYRAALYGWIYPLAVHRCLRGLAFLYRFGYLDAGRPQRVLVIEEDIPVVASAFRILHTYWDHLRALAPEVPPPPTLEVDVIGCDEIEILAPVEGTRRVTAPSGSYDLVLDHSFWLYDGSEGPLEKELQPLPPGRYVRLRRAFGLREERSLTWSAALHYDLGDLERALIAEAEGRPAEMPERKVAALRFFLQQIFRKRDFWEGQLRVIARLLQGRPTVVLLPTGGGKSLTYQYSGMLLPGMTIVVDPLISLMIDQVDNLRGFAIDMVASISSIIDTEARERIIAQMGAGKLAYVFISPERLQSDDFRQKLQDVAARLPISLAVVDEAHCVSEWGHDFRPSYLHMTHNLQKFCASAASRPTLVALTGTASFAVLTDIQAELGITDESAIVLPRSFDRKEIRFHVERVPREAKMHALKRFRSQLPYLLRVNPQRFFELSGAETNCGIVFCPHVNGELGVWEVALELGHGKCYAGKQPRSFNEQRHGKWPDFKLKVQKDFKHNRIQEIVATKSFGMGIDKPNIRYTIHICIPHSVEAFYQEAGRAGRNGKPGYAISAILYSDENWVEAMGIFNEADHRKAQKKIENIPWNSRGDLLIQLWLLYNTYRGRDDEYQRALDFWKRYVRPELKELPVGATRLLEIPFTQSRRVDDEEEETNRGALEKSIFRMVILRIVEDYTIDWNQSIFQLRVRNAAPIEIKQSLRNYLGRYKLPATADQMVQPIPEDDQEKALEAALEVLIDFVYGEIAAKRKQALRTMAELCRNFRSDRDFREAILAYLQESEFSAELRTWIGRGFDEIGLEKIRDLLGKLSSLDEIKRLVGTTRRMLDEDPGNVPLRYLSAVARALSRVESEESVLEEVVSLTLQILRLKDRLRDPDEILAALLGDLATARPELLARAADRVLRLFGTPALARRLLQGPAGSDAVVRNHAAVLLMAESLRTIRESAFYQTLVNAV
>NC_015970.1|WP_012845332.1|86527_87136_-|hypothetical-protein
MNEGDRILEAERQIRQLAEELDRLFRAANLLKSAQEQLDEVAQSSRRLVEETGKFITTAGDIVARLSEADLPRQIEAITQQVREAHERLLATLQEHVAALQSLEEEESGRLRERLENLERLQEDRFEQLRDLLGAIQKGQHEGVSALREAIQQNTTAIRSLMEEESGRLRETLKALQTRVTLVLATLGVIILLLLLLIFRAG
>NC_015970.1|WP_155816016.1|85865_86357_+|hypothetical-protein
MSRLRDATLLLTEAQQGVDQVLRGCQHLNDRVADLFEHLHAAANALQEAGFPELKERLDQQKTDLEKLQERQQEALRQFDALRKTLEYLHQSILRLAAGYNSLQLRLQATGEQLQTGFESLMLATSRLTDRIAAIETRQQRSLWTLAAVAGLVLLTLIVVLWP
>NC_015970.1|WP_014072557.1|83509_85837_+|hypothetical-protein
MSAPQLGPWKHRLTALHAELRAFLIGRARPGHTSTVFDGRVFHLRPEAYAGLRQNDRHPEAIEKAWHVFELLGRDERLAEIFPELALASLAIRTLQAGRLPAVLDTIEGIVVDEVQDLTLLELSVVVELWRRLAQRRPEPPLLLLAGDEGQTVRPSGFRWGPYKDWLSERIAPPRDYELGESLRCPANIVRTFDRAARYYRKLPREERPARQRRDSPAAPGGHLIYVATENQQQAASLIHELCEEEALVVVSLEDEVPEHIWSPALIKGLERQTVVVLNPGAVLERLDRFVSEENFAFDREDYRTEVDRLRVALSRSSETLVFLDVAPTAAQRACSLRLLGDDAVEVAPHELLNSLEQAELSLLERIQARLEEFTARIDEDPSQALQLALRARELQLRIQSLGEHIPARIAREVSRAILSATARLLVDDHPTEVDAPELQQAREAARELGLEHLRALDELVRWHRSGRTFPAALLQAACQLPDEAEWLRQALSAIAYSLHAALEHGARSPESAAVFLEDVASWLRFLDYGGNVEEAVRRLRGLAFDALLAAGNLATAEQLLEHIHPPDLLRKGRLLEARDALEEAIEVYLQAGAHTEAERVRQRLYHFRNHTLQRFRRLADQCSDPEQIPVLISMLSGAQQRLAFWYIRLCLETKHGSDDQSPLHPFLGYLEAVHAHAELLEDPELMMLGALEELSRRRHRACGAATRLLFERFGTRSMARRLLASPIGELPECSEPAVFCLAASVLETLRNCPPYQKLLAFSDHGKPTRGPAES
>NC_015970.1|WP_029961319.1|82873_83506_+|hypothetical-protein
MRRLGIILRQIAARGRPNRIKNCRNPENRGWLRTPMGGGGSGMHFYLWWAQSDSERVAPLAPTENEVFLRTIRHHDEHTPLDCGHRDDYIHLSLQELQTERIDGVDCSPWTPEQRAFIEAGEAVRIILGRPGSGKTASLWRAVERHPARHLLYLTWSRELAWQAHLNFSALTPDRTIRCWHFTRLLRALTQQDEPRLTLSESRRRFREAL
>NC_015970.1|WP_012845329.1|81040_82573_-|TIGR02710-family-CRISPR-associated-protein
MRVRFLLVRLPFQQSMVLVMKELEGEQRVAIVPVVAPGETFHEEQAYRIFQEVAAGRLPAGAEELGEFEFPDEEAAQEAARDFVKNLKESLWGEVEAFGEKQQPSSVDTVLLLTVGGSTEPLVHAIRNLDLARSRVLFICSPDSRTLVEGGEGIMQRLPDMAGLERSRYDVMVWKDPDDLAGCVAALFELYRQIRREYPGARIAANYTGGTKTMSAALVIGAVLLGWELQLNVGVRQDLRQVLAGTDVPTRVAADDVLLRLELRLVRQALDRYDYGAAEGLVQEWLRTLSLGGERRTQVLLLYQIVRGLAAWDLGQYRQALVSFGLAGEHGASWLPRLRVLAEGQEDTFELVADLLLGAARRAHQRRYDDAVVRLLRALELFGTIRLRQAHGLDVGQLEPARLPERLRETLASTGYRGAVEVETVYRLLEALGDPVGRLFAKRRTSLLEALEQSRHSRLIGGNFSIDEQTYGVVRSRLEGFLHEAARLTDQTLQAPQLPRSEVLDWVGLE
>NC_015970.1|WP_014072555.1|80006_80594_-|hypothetical-protein
MRRIALLFGLLLALPLRAQPTFDLLGGLGPARLGAGQNRSAMHGWFAAGGHLPSGVGGFLVVDLLQATAPEQSGIIWEGGYALSGVATVVAYRMTSRRLLFGTLAGPGLWQLSIDASVSGVNTAVKDHTAIGFLLGGYGLVRLGGTFTAGLLFTRRWTATEPSSVGCFVECLSRTIGNGHAGGSGLSVVIGATIR
>NC_015970.1|WP_014072561.1|95831_96767_+|hypothetical-protein
MKRSDVYQDERYIAMNPFVALQPQDVGETRIVRTWTDTNGFKHEFIIEAPRIAGEYAEQVFIALLYFTYQQRKKGHDLPSCVTVNQSDLFNIMHWPSTGRYSSRLKDSLDYYMSVKITTNTYRQRRELRILSTHVLAGYEIYTQGRRKRVRWEWAPDFLAQIQEGDHLYSNVNDYFSLSTPTSRRCFRLLQALTIPGGKPYVADLKHFAEIRMGMGSTRVFAHVARRLENALEELRAKKLGIGFITENPERIILARYPKDSAETLSIFAELPDRIKNQLPPPRLPGLAGQYEQREQVSRLILEIPVILKDG
>NC_015970.1|WP_014072562.1|97141_97678_+|hypothetical-protein
MQTLTLRTRLDPTPEQVDALQETLERFAQACNLTLEVARACRTFRKFKLQRLVYGQLRALGLSANLAIRAIARVDHRAKHFRPTSCDYDQRTLSLRGEHVSLSTTRGRLRIPMRLSPYHRYWLARARSVQGGRLLRDRRGRWYVHLIVRVPGDRAARSRITRPGSRTTARAAPQASSR
>NC_015970.1|WP_012845339.1|97769_98072_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MKRIVSATEARVHLGAIMREIVEKGEHVVVERGGRPYVVMLSVEEYEHLCKKPDRGVWRALVLRARERVREDVGDRPIPPPEEIIRTSREERDAGFLDLH
>NC_015970.1|WP_012845340.1|98046_98475_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MPGSWICIDASIVVRLVARPDDHVVLERWDAWLAEGRRLAAPTLLFYEVTNALHRYHRHGWMKEGTVRSALEAALALPVELHGDASLHERALEMATELGLAAAYDAHYLALAERLRAEFWTADGKLVRAVGARFDWVRLLGS
>NC_015970.1|WP_049772410.1|98699_98990_-|hypothetical-protein
MALLMVMGWALPVYALAEHRLRSVLRKRGESIPNQFGKPTQRPTMRRIFQMFEGIDVLLLPTLDGVQQQVLNLEAVHCQILRLLGPCVGKCCQDTS
>NC_015970.1|WP_144295526.1|99007_99496_-|hypothetical-protein
MRQRWLVVWSAQAEQREQAVLHKRVEKERQAAENAWRRRCRRAFASQEEAEATVEAQAKHYRCHRVEVHYRPVLHDEERGRPPAGAMPCRVGVCLEGALVAKAEAIAAARKRLGTFILATNELDERALPTEEMLWAYKGQGWDRSEVSAFSKTPGSLPIACF
>NC_015970.1|WP_081472097.1|99875_100256_-|DUF4277-domain-containing-protein
MTDLTTHIPHFGKQEMRFCGILQKQEDTNDQEIRNATSGSPGHRSRYLPGDWPGRVKGPPARARPTSVGEAVQAMVLKAPGFTGRPLYLTPEFFANKPLDRLLRPGLTAEILHDDSLGRALDMLHE
>NC_015970.1|WP_012845341.1|100461_100665_-|HEPN-domain-containing-protein
MKEVMDLVAKAEKFLKTAEVALTVGDYDSCASRCYYAMFFLRKRPFLPGASGLPPTRGSSVCSANIL
>NC_015970.1|WP_014072563.1|100813_101650_+|IS982-family-transposase
MDTAIIAIYCFVDDFFKARGHREDPQTQMSDAEVLTTALVAARFFGGNLEQARRLLHHPNWIPHMLSKSQFIRRLHRLAPVMQTLFQILGNYWLRHTTEPIFLIDSFPLPCCDNARIRRARLYPPQRYGKTYYGYVASKQRRFYGLKVHLLCTLEGYPVEAYLTPASYSDVRMLKALLWDLPEGALVLGDRAYNDYRLEDELAAHAAIKLLPLRKKRSKRAVAAYVVFVQQRLRRRIESVGSMLARLLPRWIHAVTARGFELKIMLCLLAYSISCALK
>NC_015970.1|WP_027614307.1|101641_101968_-|nucleotidyltransferase-domain-containing-protein
MNFWETIGKRPMDERIRAIAHRVRRFLEDQYGSGIKAVILYGSHTRGTATEDSDVDLLVVVDDALRPDEVRRSLSNLLLDILLEEGELVSVIVLPESFYKSYASCDLL

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015970_1	1.1|35460|41|NC_015970|CRISPRCasFinder	35460-35500	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	35460-35500	0	1.0
NC_015970_2	2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46205-46237	33	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	46205-46237	0	1.0
NC_015970_2	2.2|46266|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46266-46298	33	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	46266-46298	0	1.0
NC_015970_2	2.3|46327|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46327-46359	33	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	46327-46359	0	1.0
NC_015970_2	2.4|46388|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46388-46420	33	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	46388-46420	0	1.0
NC_015970_2	2.5|46449|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46449-46481	33	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	46449-46481	0	1.0
NC_015970_2	2.6|46510|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46510-46542	33	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	46510-46542	0	1.0
NC_015970_2	2.7|46571|34|NC_015970|CRISPRCasFinder,CRT	46571-46604	34	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	46571-46604	0	1.0
NC_015970_3	3.1|50279|39|NC_015970|CRT	50279-50317	39	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50279-50317	0	1.0
NC_015970_3	3.2|50356|38|NC_015970|CRT	50356-50393	38	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50356-50393	0	1.0
NC_015970_3	3.3|50432|40|NC_015970|CRT	50432-50471	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50432-50471	0	1.0
NC_015970_3	3.4|50510|34|NC_015970|CRT	50510-50543	34	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50510-50543	0	1.0
NC_015970_3	3.5|50582|40|NC_015970|CRT	50582-50621	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50582-50621	0	1.0
NC_015970_3	3.6|50660|36|NC_015970|CRT	50660-50695	36	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50660-50695	0	1.0
NC_015970_3	3.7|50734|36|NC_015970|CRT	50734-50769	36	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50734-50769	0	1.0
NC_015970_3	3.8|50279|40|NC_015970|PILER-CR,CRISPRCasFinder	50279-50318	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50279-50318	0	1.0
NC_015970_3	3.9|50356|39|NC_015970|PILER-CR,CRISPRCasFinder	50356-50394	39	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50356-50394	0	1.0
NC_015970_3	3.10|50432|41|NC_015970|PILER-CR,CRISPRCasFinder	50432-50472	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50432-50472	0	1.0
NC_015970_3	3.11|50510|35|NC_015970|PILER-CR,CRISPRCasFinder	50510-50544	35	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50510-50544	0	1.0
NC_015970_3	3.12|50582|41|NC_015970|PILER-CR,CRISPRCasFinder	50582-50622	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50582-50622	0	1.0
NC_015970_3	3.13|50660|37|NC_015970|PILER-CR,CRISPRCasFinder	50660-50696	37	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50660-50696	0	1.0
NC_015970_3	3.14|50734|37|NC_015970|PILER-CR,CRISPRCasFinder	50734-50770	37	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	50734-50770	0	1.0
NC_015970_4	4.1|58287|40|NC_015970|CRISPRCasFinder,CRT	58287-58326	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58287-58326	0	1.0
NC_015970_4	4.2|58364|36|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58364-58399	36	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58364-58399	0	1.0
NC_015970_4	4.3|58437|41|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58437-58477	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58437-58477	0	1.0
NC_015970_4	4.4|58515|39|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58515-58553	39	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58515-58553	0	1.0
NC_015970_4	4.5|58591|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58591-58630	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58591-58630	0	1.0
NC_015970_4	4.6|58668|36|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58668-58703	36	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58668-58703	0	1.0
NC_015970_4	4.7|58741|34|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58741-58774	34	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58741-58774	0	1.0
NC_015970_4	4.8|58812|39|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58812-58850	39	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58812-58850	0	1.0
NC_015970_4	4.9|58888|41|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58888-58928	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58888-58928	0	1.0
NC_015970_4	4.10|58966|43|NC_015970|CRISPRCasFinder,CRT,PILER-CR	58966-59008	43	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	58966-59008	0	1.0
NC_015970_4	4.11|59046|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR	59046-59085	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	59046-59085	0	1.0
NC_015970_4	4.12|59123|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR	59123-59162	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	59123-59162	0	1.0
NC_015970_4	4.13|59200|38|NC_015970|CRISPRCasFinder,CRT,PILER-CR	59200-59237	38	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	59200-59237	0	1.0
NC_015970_5	5.1|72695|38|NC_015970|PILER-CR,CRISPRCasFinder,CRT	72695-72732	38	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	72695-72732	0	1.0
NC_015970_5	5.2|72770|38|NC_015970|PILER-CR,CRISPRCasFinder,CRT	72770-72807	38	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	72770-72807	0	1.0
NC_015970_5	5.3|72845|39|NC_015970|PILER-CR,CRISPRCasFinder,CRT	72845-72883	39	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	72845-72883	0	1.0
NC_015970_5	5.4|72921|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT	72921-72961	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	72921-72961	0	1.0
NC_015970_5	5.5|72999|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT	72999-73045	47	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	72999-73045	0	1.0
NC_015970_5	5.6|73083|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT	73083-73125	43	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	73083-73125	0	1.0
NC_015970_5	5.6|73083|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT	73083-73125	43	AX059140	Sequence 1 from Patent WO0075335	35262-35304	0	1.0
NC_015970_5	5.6|73083|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT	73083-73125	43	NC_004735	Rhodothermus phage RM378, complete genome	35262-35304	0	1.0
NC_015970_5	5.7|73163|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT	73163-73208	46	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	73163-73208	0	1.0
NC_015970_6	6.1|79847|35|NC_015970|PILER-CR	79847-79881	35	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	55290-55324	0	1.0
NC_015970_6	6.1|79847|35|NC_015970|PILER-CR	79847-79881	35	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	79847-79881	0	1.0
NC_015970_6	6.2|79925|36|NC_015970|PILER-CR	79925-79960	36	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	55362-55397	0	1.0
NC_015970_6	6.2|79925|36|NC_015970|PILER-CR	79925-79960	36	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	79919-79954	0	1.0
NC_015970_6	6.3|79841|41|NC_015970|CRISPRCasFinder	79841-79881	41	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	55284-55324	0	1.0
NC_015970_6	6.3|79841|41|NC_015970|CRISPRCasFinder	79841-79881	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	79841-79881	0	1.0
NC_015970_6	6.4|79919|36|NC_015970|CRISPRCasFinder	79919-79954	36	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	55362-55397	0	1.0
NC_015970_6	6.4|79919|36|NC_015970|CRISPRCasFinder	79919-79954	36	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	79919-79954	0	1.0
NC_015970_7	7.1|80684|40|NC_015970|PILER-CR	80684-80723	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	80684-80723	0	1.0
NC_015970_7	7.2|80762|46|NC_015970|PILER-CR	80762-80807	46	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	80762-80807	0	1.0
NC_015970_7	7.3|80684|41|NC_015970|CRISPRCasFinder	80684-80724	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	80684-80724	0	1.0
NC_015970_7	7.4|80762|47|NC_015970|CRISPRCasFinder	80762-80808	47	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	80762-80808	0	1.0
NC_015970_8	8.1|91108|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91108-91151	44	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	65866-65909	0	1.0
NC_015970_8	8.1|91108|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91108-91151	44	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91108-91151	0	1.0
NC_015970_8	8.2|91189|40|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91189-91228	40	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	65947-65986	0	1.0
NC_015970_8	8.2|91189|40|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91189-91228	40	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91189-91228	0	1.0
NC_015970_8	8.3|91266|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91266-91306	41	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	66024-66064	0	1.0
NC_015970_8	8.3|91266|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91266-91306	41	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91266-91306	0	1.0
NC_015970_8	8.4|91344|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91344-91390	47	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	66102-66148	0	1.0
NC_015970_8	8.4|91344|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91344-91390	47	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	66186-66232	0	1.0
NC_015970_8	8.4|91344|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91344-91390	47	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91344-91390	0	1.0
NC_015970_8	8.5|91428|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91428-91470	43	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91428-91470	0	1.0
NC_015970_8	8.6|91508|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91508-91553	46	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91508-91553	0	1.0
NC_015970_8	8.7|91591|39|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91591-91629	39	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91591-91629	0	1.0
NC_015970_8	8.8|91667|45|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91667-91711	45	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91667-91711	0	1.0
NC_015970_8	8.9|91749|45|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91749-91793	45	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91749-91793	0	1.0
NC_015970_8	8.10|91831|36|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91831-91866	36	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91831-91866	0	1.0
NC_015970_8	8.11|91904|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91904-91949	46	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91904-91949	0	1.0
NC_015970_8	8.12|91987|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT	91987-92030	44	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	91987-92030	0	1.0
NC_015970_8	8.13|92068|37|NC_015970|PILER-CR,CRISPRCasFinder,CRT	92068-92104	37	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	92068-92104	0	1.0
NC_015970_8	8.14|92142|42|NC_015970|PILER-CR,CRISPRCasFinder,CRT	92142-92183	42	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	92142-92183	0	1.0
NC_015970_9	9.1|95364|38|NC_015970|PILER-CR	95364-95401	38	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	69490-69527	0	1.0
NC_015970_9	9.1|95364|38|NC_015970|PILER-CR	95364-95401	38	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	95363-95400	0	1.0
NC_015970_9	9.2|95426|57|NC_015970|PILER-CR	95426-95482	57	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	69547-69603	0	1.0
NC_015970_9	9.2|95426|57|NC_015970|PILER-CR	95426-95482	57	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	95420-95476	0	1.0
NC_015970_2	2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46205-46237	33	NC_012987	Methylorubrum extorquens AM1 plasmid p1METDI, complete sequence	38295-38327	7	0.788
NC_015970_2	2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46205-46237	33	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	782839-782871	8	0.758
NC_015970_2	2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT	46205-46237	33	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	35164-35196	9	0.727
NC_015970_2	2.7|46571|34|NC_015970|CRISPRCasFinder,CRT	46571-46604	34	KT221034	Streptomyces phage SF3, complete genome	30567-30600	10	0.706
NC_015970_3	3.4|50510|34|NC_015970|CRT	50510-50543	34	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1671305-1671338	11	0.676

1. spacer 1.1|35460|41|NC_015970|CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

cacgtcgatcggcacggcgagccgccgggctgcggcctgag	CRISPR spacer
cacgtcgatcggcacggcgagccgccgggctgcggcctgag	Protospacer
*****************************************

2. spacer 2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

caggtgcgcccctacgcggaggtgatcaagaag	CRISPR spacer
caggtgcgcccctacgcggaggtgatcaagaag	Protospacer
*********************************

3. spacer 2.2|46266|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ccagaatcagaaaacgcagcatctgaggcgatg	CRISPR spacer
ccagaatcagaaaacgcagcatctgaggcgatg	Protospacer
*********************************

4. spacer 2.3|46327|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

cacgaccggtgagcacgtcgaggatccgaagcg	CRISPR spacer
cacgaccggtgagcacgtcgaggatccgaagcg	Protospacer
*********************************

5. spacer 2.4|46388|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tcaagaaggtgttgccataatgaaaccgcgata	CRISPR spacer
tcaagaaggtgttgccataatgaaaccgcgata	Protospacer
*********************************

6. spacer 2.5|46449|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ctgtccaccttctgcggccgaaaaagacggcgg	CRISPR spacer
ctgtccaccttctgcggccgaaaaagacggcgg	Protospacer
*********************************

7. spacer 2.6|46510|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ctttgcgctgatctttacggcccgcgtgctttt	CRISPR spacer
ctttgcgctgatctttacggcccgcgtgctttt	Protospacer
*********************************

8. spacer 2.7|46571|34|NC_015970|CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ttacacgcatggaggcgtagccgcccggcgggag	CRISPR spacer
ttacacgcatggaggcgtagccgcccggcgggag	Protospacer
**********************************

9. spacer 3.1|50279|39|NC_015970|CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggtgatcgggcgtatccgggacaaactccagagacacgg	CRISPR spacer
ggtgatcgggcgtatccgggacaaactccagagacacgg	Protospacer
***************************************

10. spacer 3.2|50356|38|NC_015970|CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggagaaagtaatccggggctggctggccgacggatatc	CRISPR spacer
ggagaaagtaatccggggctggctggccgacggatatc	Protospacer
**************************************

11. spacer 3.3|50432|40|NC_015970|CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gaatacggcggaagcaaactggttaacggtgcggtcgtct	CRISPR spacer
gaatacggcggaagcaaactggttaacggtgcggtcgtct	Protospacer
****************************************

12. spacer 3.4|50510|34|NC_015970|CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

aaacggagatgccatgcggtcgctccgtgaaatc	CRISPR spacer
aaacggagatgccatgcggtcgctccgtgaaatc	Protospacer
**********************************

13. spacer 3.5|50582|40|NC_015970|CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tgctatgaacagcgcgatttatcagccgtttttgaatgag	CRISPR spacer
tgctatgaacagcgcgatttatcagccgtttttgaatgag	Protospacer
****************************************

14. spacer 3.6|50660|36|NC_015970|CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gatggatcggccgatcgcctttcaccgggcattcgc	CRISPR spacer
gatggatcggccgatcgcctttcaccgggcattcgc	Protospacer
************************************

15. spacer 3.7|50734|36|NC_015970|CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gttgtttaaggatggtttcttttacaatgcgcttga	CRISPR spacer
gttgtttaaggatggtttcttttacaatgcgcttga	Protospacer
************************************

16. spacer 3.8|50279|40|NC_015970|PILER-CR,CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggtgatcgggcgtatccgggacaaactccagagacacggg	CRISPR spacer
ggtgatcgggcgtatccgggacaaactccagagacacggg	Protospacer
****************************************

17. spacer 3.9|50356|39|NC_015970|PILER-CR,CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggagaaagtaatccggggctggctggccgacggatatcg	CRISPR spacer
ggagaaagtaatccggggctggctggccgacggatatcg	Protospacer
***************************************

18. spacer 3.10|50432|41|NC_015970|PILER-CR,CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gaatacggcggaagcaaactggttaacggtgcggtcgtctg	CRISPR spacer
gaatacggcggaagcaaactggttaacggtgcggtcgtctg	Protospacer
*****************************************

19. spacer 3.11|50510|35|NC_015970|PILER-CR,CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

aaacggagatgccatgcggtcgctccgtgaaatcg	CRISPR spacer
aaacggagatgccatgcggtcgctccgtgaaatcg	Protospacer
***********************************

20. spacer 3.12|50582|41|NC_015970|PILER-CR,CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tgctatgaacagcgcgatttatcagccgtttttgaatgaga	CRISPR spacer
tgctatgaacagcgcgatttatcagccgtttttgaatgaga	Protospacer
*****************************************

21. spacer 3.13|50660|37|NC_015970|PILER-CR,CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gatggatcggccgatcgcctttcaccgggcattcgcg	CRISPR spacer
gatggatcggccgatcgcctttcaccgggcattcgcg	Protospacer
*************************************

22. spacer 3.14|50734|37|NC_015970|PILER-CR,CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gttgtttaaggatggtttcttttacaatgcgcttgag	CRISPR spacer
gttgtttaaggatggtttcttttacaatgcgcttgag	Protospacer
*************************************

23. spacer 4.1|58287|40|NC_015970|CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tggcacccagatcgtcccgagcccggtcaatatgcacggt	CRISPR spacer
tggcacccagatcgtcccgagcccggtcaatatgcacggt	Protospacer
****************************************

24. spacer 4.2|58364|36|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ttgaaaagcttgtgctcaacgaacaggcgcgtatgc	CRISPR spacer
ttgaaaagcttgtgctcaacgaacaggcgcgtatgc	Protospacer
************************************

25. spacer 4.3|58437|41|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

aggatcctcaggggcagcagcgcattccggactgggaggcc	CRISPR spacer
aggatcctcaggggcagcagcgcattccggactgggaggcc	Protospacer
*****************************************

26. spacer 4.4|58515|39|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gatgagccagacgaggggtgggtaaataagtactatgac	CRISPR spacer
gatgagccagacgaggggtgggtaaataagtactatgac	Protospacer
***************************************

27. spacer 4.5|58591|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

catcgacgggcgtgagatggacgaggatgcgctctacgag	CRISPR spacer
catcgacgggcgtgagatggacgaggatgcgctctacgag	Protospacer
****************************************

28. spacer 4.6|58668|36|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ctggactggtgccagcgctacctcggcgaagaggcc	CRISPR spacer
ctggactggtgccagcgctacctcggcgaagaggcc	Protospacer
************************************

29. spacer 4.7|58741|34|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

cgacgatcgcacgctgcttatggcgctcattccc	CRISPR spacer
cgacgatcgcacgctgcttatggcgctcattccc	Protospacer
**********************************

30. spacer 4.8|58812|39|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tcatcgaagagatgatggacgtgctcgaaaagcttgagc	CRISPR spacer
tcatcgaagagatgatggacgtgctcgaaaagcttgagc	Protospacer
***************************************

31. spacer 4.9|58888|41|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gcaagcgctcagcaggcattgtcgttgagctgtagccagca	CRISPR spacer
gcaagcgctcagcaggcattgtcgttgagctgtagccagca	Protospacer
*****************************************

32. spacer 4.10|58966|43|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

cgacttgaaagaaaggttcgacgtgctcccgtacgagatccca	CRISPR spacer
cgacttgaaagaaaggttcgacgtgctcccgtacgagatccca	Protospacer
*******************************************

33. spacer 4.11|59046|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tcaaggatgaggtgctgggatggaccaacagagccaacag	CRISPR spacer
tcaaggatgaggtgctgggatggaccaacagagccaacag	Protospacer
****************************************

34. spacer 4.12|59123|40|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gcgacgtggtgagtcccgacaccggcccggagagtgctat	CRISPR spacer
gcgacgtggtgagtcccgacaccggcccggagagtgctat	Protospacer
****************************************

35. spacer 4.13|59200|38|NC_015970|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggatcaatgagcttggtttccaggagactcccagcggc	CRISPR spacer
ggatcaatgagcttggtttccaggagactcccagcggc	Protospacer
**************************************

36. spacer 5.1|72695|38|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gtaaacgctcccgagaaggtgtgggataaagtgaaaga	CRISPR spacer
gtaaacgctcccgagaaggtgtgggataaagtgaaaga	Protospacer
**************************************

37. spacer 5.2|72770|38|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tggaggggttcagaggatgggaatttgcgggcggagaa	CRISPR spacer
tggaggggttcagaggatgggaatttgcgggcggagaa	Protospacer
**************************************

38. spacer 5.3|72845|39|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tgaaatcgatcttcgactggtctagcgactcaagcttga	CRISPR spacer
tgaaatcgatcttcgactggtctagcgactcaagcttga	Protospacer
***************************************

39. spacer 5.4|72921|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gggacccccgtgtgtgctgcagcttgtctgccacgctgtgc	CRISPR spacer
gggacccccgtgtgtgctgcagcttgtctgccacgctgtgc	Protospacer
*****************************************

40. spacer 5.5|72999|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

cgtctccattcttccacgaatggagaacctgaagtggcgccagtcca	CRISPR spacer
cgtctccattcttccacgaatggagaacctgaagtggcgccagtcca	Protospacer
***********************************************

41. spacer 5.6|73083|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gttttcgttgggaatcgtgcattcatctgcaatgatatccagc	CRISPR spacer
gttttcgttgggaatcgtgcattcatctgcaatgatatccagc	Protospacer
*******************************************

42. spacer 5.6|73083|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to AX059140 (Sequence 1 from Patent WO0075335) position: , mismatch: 0, identity: 1.0

gttttcgttgggaatcgtgcattcatctgcaatgatatccagc	CRISPR spacer
gttttcgttgggaatcgtgcattcatctgcaatgatatccagc	Protospacer
*******************************************

43. spacer 5.6|73083|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_004735 (Rhodothermus phage RM378, complete genome) position: , mismatch: 0, identity: 1.0

gttttcgttgggaatcgtgcattcatctgcaatgatatccagc	CRISPR spacer
gttttcgttgggaatcgtgcattcatctgcaatgatatccagc	Protospacer
*******************************************

44. spacer 5.7|73163|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

cgaagcccgtgacaagctcgggtggccgctcaaggtggaatatcgt	CRISPR spacer
cgaagcccgtgacaagctcgggtggccgctcaaggtggaatatcgt	Protospacer
**********************************************

45. spacer 6.1|79847|35|NC_015970|PILER-CR matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

gtcagcggaacgctctactacaacccatatacaga	CRISPR spacer
gtcagcggaacgctctactacaacccatatacaga	Protospacer
***********************************

46. spacer 6.1|79847|35|NC_015970|PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gtcagcggaacgctctactacaacccatatacaga	CRISPR spacer
gtcagcggaacgctctactacaacccatatacaga	Protospacer
***********************************

47. spacer 6.2|79925|36|NC_015970|PILER-CR matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

tgttggcctcgctggagcaatgggccagcgaacatg	CRISPR spacer
tgttggcctcgctggagcaatgggccagcgaacatg	Protospacer
************************************

48. spacer 6.2|79925|36|NC_015970|PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tgttggcctcgctggagcaatgggccagcgaacatg	CRISPR spacer
tgttggcctcgctggagcaatgggccagcgaacatg	Protospacer
************************************

49. spacer 6.3|79841|41|NC_015970|CRISPRCasFinder matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

cgcctggtcagcggaacgctctactacaacccatatacaga	CRISPR spacer
cgcctggtcagcggaacgctctactacaacccatatacaga	Protospacer
*****************************************

50. spacer 6.3|79841|41|NC_015970|CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

cgcctggtcagcggaacgctctactacaacccatatacaga	CRISPR spacer
cgcctggtcagcggaacgctctactacaacccatatacaga	Protospacer
*****************************************

51. spacer 6.4|79919|36|NC_015970|CRISPRCasFinder matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

tgttggcctcgctggagcaatgggccagcgaacatg	CRISPR spacer
tgttggcctcgctggagcaatgggccagcgaacatg	Protospacer
************************************

52. spacer 6.4|79919|36|NC_015970|CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tgttggcctcgctggagcaatgggccagcgaacatg	CRISPR spacer
tgttggcctcgctggagcaatgggccagcgaacatg	Protospacer
************************************

53. spacer 7.1|80684|40|NC_015970|PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gaaagcacggataccagatgtcgtgaagaagagacatatc	CRISPR spacer
gaaagcacggataccagatgtcgtgaagaagagacatatc	Protospacer
****************************************

54. spacer 7.2|80762|46|NC_015970|PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tcgggtcgtgatcgtcagcgtgttggcgttgccgaggccgaatggg	CRISPR spacer
tcgggtcgtgatcgtcagcgtgttggcgttgccgaggccgaatggg	Protospacer
**********************************************

55. spacer 7.3|80684|41|NC_015970|CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gaaagcacggataccagatgtcgtgaagaagagacatatca	CRISPR spacer
gaaagcacggataccagatgtcgtgaagaagagacatatca	Protospacer
*****************************************

56. spacer 7.4|80762|47|NC_015970|CRISPRCasFinder matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tcgggtcgtgatcgtcagcgtgttggcgttgccgaggccgaatgggc	CRISPR spacer
tcgggtcgtgatcgtcagcgtgttggcgttgccgaggccgaatgggc	Protospacer
***********************************************

57. spacer 8.1|91108|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

aagaactggctcatcgagatcggcgggcaggcttatggtctgta	CRISPR spacer
aagaactggctcatcgagatcggcgggcaggcttatggtctgta	Protospacer
********************************************

58. spacer 8.1|91108|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

aagaactggctcatcgagatcggcgggcaggcttatggtctgta	CRISPR spacer
aagaactggctcatcgagatcggcgggcaggcttatggtctgta	Protospacer
********************************************

59. spacer 8.2|91189|40|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

tattcctaacctgaacagcgacgtcataaccgacgagccc	CRISPR spacer
tattcctaacctgaacagcgacgtcataaccgacgagccc	Protospacer
****************************************

60. spacer 8.2|91189|40|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tattcctaacctgaacagcgacgtcataaccgacgagccc	CRISPR spacer
tattcctaacctgaacagcgacgtcataaccgacgagccc	Protospacer
****************************************

61. spacer 8.3|91266|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

tacatcacgattcgagatcgcacgcggcgagtactttctcg	CRISPR spacer
tacatcacgattcgagatcgcacgcggcgagtactttctcg	Protospacer
*****************************************

62. spacer 8.3|91266|41|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tacatcacgattcgagatcgcacgcggcgagtactttctcg	CRISPR spacer
tacatcacgattcgagatcgcacgcggcgagtactttctcg	Protospacer
*****************************************

63. spacer 8.4|91344|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

ggcaaagagactgtatgccaggcggacgtcaccccagcgcttcgacg	CRISPR spacer
ggcaaagagactgtatgccaggcggacgtcaccccagcgcttcgacg	Protospacer
***********************************************

64. spacer 8.4|91344|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

ggcaaagagactgtatgccaggcggacgtcaccccagcgcttcgacg	CRISPR spacer
ggcaaagagactgtatgccaggcggacgtcaccccagcgcttcgacg	Protospacer
***********************************************

65. spacer 8.4|91344|47|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggcaaagagactgtatgccaggcggacgtcaccccagcgcttcgacg	CRISPR spacer
ggcaaagagactgtatgccaggcggacgtcaccccagcgcttcgacg	Protospacer
***********************************************

66. spacer 8.5|91428|43|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gggatgagcagtcggcggtgtccatcgtgctgttcatgtacgg	CRISPR spacer
gggatgagcagtcggcggtgtccatcgtgctgttcatgtacgg	Protospacer
*******************************************

67. spacer 8.6|91508|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggcgaacgggatcgtgacgtgctttaacgtgtttgtgtgaagaaaa	CRISPR spacer
ggcgaacgggatcgtgacgtgctttaacgtgtttgtgtgaagaaaa	Protospacer
**********************************************

68. spacer 8.7|91591|39|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ggcatcaagcgggttcttacccgtctgcttcgagagcgc	CRISPR spacer
ggcatcaagcgggttcttacccgtctgcttcgagagcgc	Protospacer
***************************************

69. spacer 8.8|91667|45|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

tggcgcgcttcagggcgggcaagtttgtaatcttaagtattcaga	CRISPR spacer
tggcgcgcttcagggcgggcaagtttgtaatcttaagtattcaga	Protospacer
*********************************************

70. spacer 8.9|91749|45|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ccaaatcgacaaggacggcaacatcgtcgtcggcggccgggtcat	CRISPR spacer
ccaaatcgacaaggacggcaacatcgtcgtcggcggccgggtcat	Protospacer
*********************************************

71. spacer 8.10|91831|36|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

caaaactacggtgggagccatgaagaagatcaaaga	CRISPR spacer
caaaactacggtgggagccatgaagaagatcaaaga	Protospacer
************************************

72. spacer 8.11|91904|46|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcgtcgtccctgcgggcggcgcaacgagtcgcggagcgggagtg	CRISPR spacer
ttgcgtcgtccctgcgggcggcgcaacgagtcgcggagcgggagtg	Protospacer
**********************************************

73. spacer 8.12|91987|44|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

atgaagaaggtaacgagcgggaatttgtagacgtggcaaaggat	CRISPR spacer
atgaagaaggtaacgagcgggaatttgtagacgtggcaaaggat	Protospacer
********************************************

74. spacer 8.13|92068|37|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ctcaggacgccccgttcgggtttgccttctactggca	CRISPR spacer
ctcaggacgccccgttcgggtttgccttctactggca	Protospacer
*************************************

75. spacer 8.14|92142|42|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

acaatcagttccgagccgtcggggaatatgcgtcgtacacta	CRISPR spacer
acaatcagttccgagccgtcggggaatatgcgtcgtacacta	Protospacer
******************************************

76. spacer 9.1|95364|38|NC_015970|PILER-CR matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

ccgctttattttgactcgaaatgcacaattatgacctg	CRISPR spacer
ccgctttattttgactcgaaatgcacaattatgacctg	Protospacer
**************************************

77. spacer 9.1|95364|38|NC_015970|PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

ccgctttattttgactcgaaatgcacaattatgacctg	CRISPR spacer
ccgctttattttgactcgaaatgcacaattatgacctg	Protospacer
**************************************

78. spacer 9.2|95426|57|NC_015970|PILER-CR matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 0, identity: 1.0

gaggcatctccaccccacccgcgaaaatcggccaatttcgccgattccggatcggtc	CRISPR spacer
gaggcatctccaccccacccgcgaaaatcggccaatttcgccgattccggatcggtc	Protospacer
*********************************************************

79. spacer 9.2|95426|57|NC_015970|PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 0, identity: 1.0

gaggcatctccaccccacccgcgaaaatcggccaatttcgccgattccggatcggtc	CRISPR spacer
gaggcatctccaccccacccgcgaaaatcggccaatttcgccgattccggatcggtc	Protospacer
*********************************************************

80. spacer 2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NC_012987 (Methylorubrum extorquens AM1 plasmid p1METDI, complete sequence) position: , mismatch: 7, identity: 0.788

caggtgcgcccctacgcggaggtgatcaagaag	CRISPR spacer
gatgcgcgcgcctacgcggcggtgatcaacacg	Protospacer
 * *.**** ********* ********* * *

81. spacer 2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.758

caggtgcgcccctacgcggaggtgatcaagaag	CRISPR spacer
gccgagcgcccctacgcggcggtgatcaacacc	Protospacer
   * ************** ********* *  

82. spacer 2.1|46205|33|NC_015970|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

caggtgcgcccctacgcggaggtgatcaagaag	CRISPR spacer
acggtgcggccctacgcggagctgatccccgac	Protospacer
  ****** ************ *****   .* 

83. spacer 2.7|46571|34|NC_015970|CRISPRCasFinder,CRT matches to KT221034 (Streptomyces phage SF3, complete genome) position: , mismatch: 10, identity: 0.706

ttacacgcatggaggcgtagccgcccggcgggag	CRISPR spacer
ccccgtgcatggaggcgtatccgcccgacgagca	Protospacer
.. *..************* *******.**.* .

84. spacer 3.4|50510|34|NC_015970|CRT matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 11, identity: 0.676

aaacggagatgccatgcggtcgctccgtgaaatc	CRISPR spacer
ggcgatcggtgccttgcgggcgctccgtgaaatt	Protospacer
..  .  *.**** ***** *************.

2. NC_015966

CRISPR-Cas detection and classification

Crispr_ID: NC_015966_1

• CRISPR_ID: NC_015966_1
• CRISPR_location: 85116-85208
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_015966_1

Consensus_repeat	Method
CGGCGGCCCTTGCAGGTCTCGCAG	CRISPRCasFinder

spacers of NC_015966_1

>1.1|85140|45|NC_015966|CRISPRCasFinder
GTCACGTGCACGTCCGGCAGAAAGTTCATCTCCAGCTTCACCACG

CRISPR arrays and Neighbor proteins around NC_015966_1

CRISPR arrays

The CRISPR arrays of NC_015966_1

>merge|NC_015966|1|85116-85208|CRISPRCasFinder
CGGCGGCCCTTGCAGGTCTCGCAGGTCACGTGCACGTCCGGCAGAAAGTTCATCTCCAGCTTCACCACGCCGGCGCCCTTGCAGGTCTCGCAG

>NC_015966|1|1|85116-85208|CRISPRCasFinder
CGGCGGCCCTTGCAGGTCTCGCAG	GTCACGTGCACGTCCGGCAGAAAGTTCATCTCCAGCTTCACCACG
CCGGCGCCCTTGCAGGTCTCGCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_012842612.1|97242_97650_+|hypothetical-protein	unknown	unknown	gnl|CDD|376849
NC_015966.1|WP_014065808.1|70973_72479_-|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl|CDD|236447
NC_015966.1|WP_014065813.1|79549_81433_-|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl|CDD|236451
NC_015966.1|WP_014065809.1|72731_75239_+|peptidase-M14	unknown	unknown	gnl|CDD|349457
NC_015966.1|WP_014065815.1|82438_82828_-|HEPN-domain-containing-protein	unknown	unknown	gnl|CDD|224807
NC_015966.1|WP_014065811.1|76584_79098_-|glycoside-hydrolase-family-9-protein	unknown	unknown	gnl|CDD|199881
NC_015966.1|WP_014065816.1|82824_83184_-|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|143393
NC_015966.1|WP_012842613.1|97649_98567_+|hypothetical-protein	unknown	unknown	gnl|CDD|235503
NC_015966.1|WP_012842604.1|88272_88590_+|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014065814.1|81685_82306_-|DUF4405-domain-containing-protein	unknown	unknown	gnl|CDD|379580
NC_015966.1|WP_012842611.1|96455_97241_+|membrane-protein	unknown	unknown	gnl|CDD|224755
NC_015966.1|WP_014065822.1|92250_93189_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014065817.1|83370_84474_+|hypothetical-protein	unknown	unknown	gnl|CDD|271333
NC_015966.1|WP_014065810.1|75242_76583_-|thymidine-phosphorylase	unknown	unknown	gnl|CDD|180276
NC_015966.1|WP_014065819.1|87598_88192_+|MarC-family-protein	unknown	unknown	gnl|CDD|225006
NC_015966.1|WP_155815957.1|88670_91100_-|glycoside-hydrolase-family-95-protein	unknown	unknown	gnl|CDD|379625
NC_015966.1|WP_014065824.1|93589_96355_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_015966.1|WP_014065821.1|91185_92184_-|voltage-dependent-potassium-channel-subunit-beta	unknown	unknown	gnl|CDD|381369
NC_015966.1|WP_014065812.1|79215_79467_-|50S-ribosomal-protein-L31	unknown	unknown	gnl|CDD|376487
NC_015966.1|WP_014065823.1|93291_93474_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_014065808.1|70973_72479_-|F0F1-ATP-synthase-subunit-beta	gnl|CDD|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NC_015966.1|WP_014065813.1|79549_81433_-|phosphomethylpyrimidine-synthase-ThiC	gnl|CDD|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_015966.1|WP_014065809.1|72731_75239_+|peptidase-M14	gnl|CDD|349457	cd06238, M14-like, Peptidase M14-like domain; uncharacterized subgroup. Peptidase M14-like domain of a functionally uncharacterized subgroup of the M14 family of metallocarboxypeptidases (MCPs). The M14 family are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Two major subfamilies of the M14 family, defined based on sequence and structural homology, are the A/B and N/E subfamilies. Enzymes belonging to the A/B subfamily are normally synthesized as inactive precursors containing preceding signal peptide, followed by an N-terminal pro-region linked to the enzyme; these proenzymes are called procarboxypeptidases. The A/B enzymes can be further divided based on their substrate specificity; Carboxypeptidase A-like (CPA-like) enzymes favor hydrophobic residues while carboxypeptidase B-like (CPB-like) enzymes only cleave the basic residues lysine or arginine. The A forms have slightly different specificities, with Carboxypeptidase A1 (CPA1) preferring aliphatic and small aromatic residues, and CPA2 preferring the bulky aromatic side chains. Enzymes belonging to the N/E subfamily enzymes are not produced as inactive precursors and instead rely on their substrate specificity and subcellular compartmentalization to prevent inappropriate cleavage. They contain an extra C-terminal transthyretin-like domain, thought to be involved in folding or formation of oligomers. MCPs can also be classified based on their involvement in specific physiological processes; the pancreatic MCPs participate only in alimentary digestion and include carboxypeptidase A and B (A/B subfamily), while others, namely regulatory MCPs or the N/E subfamily, are involved in more selective reactions, mainly in non-digestive tissues and fluids, acting on blood coagulation/fibrinolysis, inflammation and local anaphylaxis, pro-hormone and neuropeptide processing, cellular response and others. Another MCP subfamily, is that of succinylglutamate desuccinylase /aspartoacylase, which hydrolyzes N-acetyl-L-aspartate (NAA), and deficiency in which is the established cause of Canavan disease. Another subfamily (referred to as subfamily C) includes an exceptional type of activity in the MCP family, that of dipeptidyl-peptidase activity of gamma-glutamyl-(L)-meso-diaminopimelate peptidase I which is involved in bacterial cell wall metabolism.	2.89503e-106
NC_015966.1|WP_014065815.1|82438_82828_-|HEPN-domain-containing-protein	gnl|CDD|224807	COG1895, COG1895, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN [Function unknown].	7.62396e-22
NC_015966.1|WP_014065811.1|76584_79098_-|glycoside-hydrolase-family-9-protein	gnl|CDD|199881	cd02850, E_set_Cellulase_N, N-terminal Early set domain associated with the catalytic domain of cellulase. E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.	3.24765e-20
NC_015966.1|WP_014065816.1|82824_83184_-|nucleotidyltransferase-domain-containing-protein	gnl|CDD|143393	cd05403, NT_KNTase_like, Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins. S. aureus KNTase is a plasmid encoded enzyme which confers resistance to a wide range of aminoglycoside antibiotics which have a 4'- or 4''-hydroxyl group in the equatorial position, such as kanamycin A. This enzyme transfers a nucleoside monophosphate group from a nucleotide (ATP,GTP, or UTP) to the 4'-hydroxyl group of kanamycin A. This enzyme is a homodimer, having two NT active sites. The nucleotide and antibiotic binding sites of each active site include residues from each monomer. Included in this subgroup is Escherichia coli AadA5 which confers resistance to the antibiotic spectinomycin and is a putative aminoglycoside-3'-adenylyltransferase. It is part of the aadA5 cassette of a class 1 integron. This subgroup also includes Haemophilus influenzae HI0073 which forms a 2:2 heterotetramer with an unrelated protein HI0074. Structurally HI0074 is related to the substrate-binding domain of S. aureus KNTase. The genes encoding HI0073 and HI0074 form an operon. Little is known about the substrate specificity or function of two-component NTs. The characterized members of this subgroup may not be representive of the function of this subgroup. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, co-ordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are conserved in this subgroup.	9.8039e-14
NC_015966.1|WP_012842613.1|97649_98567_+|hypothetical-protein	gnl|CDD|235503	PRK05561, PRK05561, DNA topoisomerase 4 subunit A.	0.00421997
NC_015966.1|WP_012842612.1|97242_97650_+|hypothetical-protein	gnl|CDD|376849	pfam02601, Exonuc_VII_L, Exonuclease VII, large subunit. This family consist of exonuclease VII, large subunit EC:3.1.11.6 This enzyme catalyzes exonucleolytic cleavage in either 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. This exonuclease VII enzyme is composed of one large subunit and 4 small ones.	0.00590528
NC_015966.1|WP_014065814.1|81685_82306_-|DUF4405-domain-containing-protein	gnl|CDD|379580	pfam14358, DUF4405, Domain of unknown function (DUF4405). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is approximately 50 amino acids in length. There are two conserved histidines that may be functionally important. This family is N-terminally truncated compared to other members of the clan.	4.20228e-15
NC_015966.1|WP_012842611.1|96455_97241_+|membrane-protein	gnl|CDD|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	1.25071e-10
NC_015966.1|WP_014065817.1|83370_84474_+|hypothetical-protein	gnl|CDD|271333	cd14963, NHL_like_5, Uncharacterized NHL-repeat domain in bacterial proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	9.13615e-10
NC_015966.1|WP_014065810.1|75242_76583_-|thymidine-phosphorylase	gnl|CDD|180276	PRK05820, deoA, thymidine phosphorylase; Reviewed.	0
NC_015966.1|WP_014065819.1|87598_88192_+|MarC-family-protein	gnl|CDD|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	7.63581e-34
NC_015966.1|WP_155815957.1|88670_91100_-|glycoside-hydrolase-family-95-protein	gnl|CDD|379625	pfam14498, Glyco_hyd_65N_2, Glycosyl hydrolase family 65, N-terminal domain. This domain represents a domain found to the N-terminus of the glycosyl hydrolase 65 family catalytic domain.	6.83868e-57
NC_015966.1|WP_014065824.1|93589_96355_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	3.76658e-86
NC_015966.1|WP_014065821.1|91185_92184_-|voltage-dependent-potassium-channel-subunit-beta	gnl|CDD|381369	cd19143, AKR_AKR6C1_2, AKR6C family of aldo-keto reductase (AKR). Voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa are founding members of aldo-keto reductase family 6 member C1 (AKR6C1) and C2 (AKR6C2), respectively. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	0
NC_015966.1|WP_014065812.1|79215_79467_-|50S-ribosomal-protein-L31	gnl|CDD|376487	pfam01197, Ribosomal_L31, Ribosomal protein L31.	3.08907e-31

Protein sequences

>NC_015966.1|WP_014065817.1|83370_84474_+|hypothetical-protein
MSGRCFWPISLLLLWLGCSGASEPGGFRAMLVPVDTIHLQEPDTLFLGEFLSVTTTLNPFRLYVPDFRLNRVVVYDSLGRPLQVIGHPGFDEPGTLLRPYYVLVLGHQLYVQEAYNRISLFTTAGEFLGRRRLPAGYDPYYPFRSLSDRLLVVSVAYQEPCSLPTEPACPETRVVSEVDTALTRVWRRWGAFPELYQKYALAPRQAMLDVLLKAALVVIGYTLDPSLYLYAVTDSGGVFKRRIALEHSAWRNPPEEMTVDLALNNRARWEALMLQSSQVRGVYFVADTLVLVHFDNLARGYFRAPQQRDYTRVLPYGVLVSLSGAWQQALELPGPVLGRDEAFHLYIRLSDEPDRRLIGRFRVEVRR
>NC_015966.1|WP_014065816.1|82824_83184_-|nucleotidyltransferase-domain-containing-protein
MPTHNSITGMPRLQPEVQHALAFTRQWLQRAYGERLHHLILYGSQARGEAHAESDVDLILVLQGPVDIATELKRLTVLKLELLDRFGRYVSFQPVDVHTFQDTSHPFFRNVHAEGISLL
>NC_015966.1|WP_014065815.1|82438_82828_-|HEPN-domain-containing-protein
MTERQRALLNRAHQALESARRLHAYGDTEGAINRAYYAMFYAASAVLLLKGEAPRTHHGVHHRFHLHFVASGDLPRELSAALSYALELRTRADYEISIDFDPQIATELLAEAARFVTTIEAWLQEISPD
>NC_015966.1|WP_014065814.1|81685_82306_-|DUF4405-domain-containing-protein
MKQVQRNFVVDLAAFVAFVLLTTTGVLLRYILPPGSGRFTTLWGLDRHTWGQIHFWIALILLGILAIHLVLHWKWIVCMVKGRPTEGSGWRMALAVVGLIGLLGLAVAPLLSPVERKELPAGQRGVAATEQRETVVPLVTGAMSLEDVARRLEVPVPTLLRTLGLPGDMAPETRLSQLRRQYGLTLHEVRRRLQTLTTTRADSLKP
>NC_015966.1|WP_014065813.1|79549_81433_-|phosphomethylpyrimidine-synthase-ThiC
MIPKPPAAIRRVYVQGNRYPELRVPFKEVQLSPTRLPDGSLEPNDPVLLYDTRGPWGDPDFHGDIRQGLPPLRRPWIEARGDVEEYDGRPVQPIDDGYRNEEERRRAEQRGKLHRWPGPRRRPLRGKNGAAVTQMYYARQGIITPEMEFVAIRENQRRERLIELQKEPGDRWSLAFQHPGQPWGAQIPPVITPEFVRDEVARGRAIIPCNVNHPECEPMIIGRNFLVKINANIGTSAVSSSIDEEVEKLLWAIYWGADTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVGGKPEELTWEIFRDTLIEQCEQGVDYMTIHAGVRLAYIPLTANRRTGIVSRGGSIIAKWCLAHHRENFLYTHFEEICEILRQYDVSISLGDGLRPGSIQDANDEAQFAELKTLGELTRIAWKYDVQVMIEGPGHIPMHLIKENVDRELEDCYEAPFYTLGPLVTDIAPAYDHITSAIGAAMIGWYGAAMLCYVTPKEHLGLPNKNDVREGVIAYKIAAHAADLAKGHPGAQYWDNALSKARFEFRWEDQFNLSLDPERAREYHDETLPAEGAKLAHFCSMCGPKFCSMKITEEIRAMAAEKGVDARQVIEEGLEEKAREFREKGAEIYTAP
>NC_015966.1|WP_014065812.1|79215_79467_-|50S-ribosomal-protein-L31
MKKGLHPEYNLITVRLADGTEFQIRSTMKGPVYVSDVDATNHPFYTGVRQFVDRAGRVEKFMRRYGKVTSQGHQKPEAEEEGK
>NC_015966.1|WP_014065811.1|76584_79098_-|glycoside-hydrolase-family-9-protein
MRRYLLLLSWLLVRPGFGQSEGFVLNEREYFEREGVSVMVFQDFYPEGHQSGVTLIQHGERVAANGDVRLEATPGQWQPVPRLLRREVHPERNEVVAYLAYPDPERDRKGFNPIFYPDLHLTYRVRVRGEADGVRIIVDLDEPLPEAWAGRVGFNLELFPGALFGKSWYMDDAAGIFPRQPNGPVRVNDAGEVEAVPLATGRRLLVAPESDALRLEIESLRGELVLYDGRVQHDNGWFVVRTTIPAGVTTNALEWVVRPHVIPGWRYGPVLQVSQVGYHPRQPKVAVLELDARDDLQGTVYLLRLGRDGATDTVLAGPPVPWNGRFLRYRYAHFDFSHVTRPGLYVLTFRDVRSHPFRIAPDVYQRHVWQPTLEFFLPVQMCHMRVEQQYRVWHGACHLDDARMAPPDTNHIDGYVQGPELRAPYAPGEHVPGLNVGGWHDAGDNDLRIESQADEVFILATMYELFDVLKTYDNTTINQRRRLTQIHQPDGRPDVLQQIEHGVLSILGGYRALGRLYRGIIAPTLKQYVLIGDPANSTDNRVYDPSVPPETLSALRVDARDPRWVVTTADDRWVFTESNPAHEYKGIAALAAAGRVLRAYNPELARACVEAAEALWQQERDTSRGFNERVVAAVELFRTTGRDLYRRTLLNDRNRIVARIGSVGWAVGAILPTLGDSAFAEAVRAAVARYMDDVHRLQQENPYGVPYRPRIWGAGWDIQRFGVRQYLLHRAFPDLVPPDYVFNALNFVLGVHPGRNTAAFASGVGARSVTVAYGFNRADWTYIPGGVVSGTALIRPDFPELKEFPYLWQQAEYVMGGGATHFMLLVLAADQLLNATH
>NC_015966.1|WP_014065810.1|75242_76583_-|thymidine-phosphorylase
MPDVVELIITKRDGGHLAPNDLRWLVQAYTHDEVPDYQMSAFLMAAFIRGLNEAEMDALTDAMLHSGRVLDLSDLPGRKVDKHSTGGVGDKVSLILAPLVAACGVPVPMISGRGLGHTGGTLDKLESIPGLRTDLSIEAFRRQLRELGVVMIGQTDEIAPADRKLYALRDVTGTIESIPLIAASILSKKLAEGADALVFDVKCGRGAFMQQEADARRLAETLVGIATRAGRPAVAWLTDMNVPLGRAVGNWPEVVESLRALRGDFEGIEDLIEVTLALAGEMLWLGGVAETPEAGRRLARAALTDGRAFERFCAMVRAQGGDVRVLERPETRPDAEPAGEVRAPDGIRGYVADLDARAVGRLAVHLGAGRRVKEDPVDPTAGLVLHRKPGDPVAPGDVLATLYTHRRDRLEDFQQALLAAYRFAETPPPARPLLLARYAEGRWRTP
>NC_015966.1|WP_014065809.1|72731_75239_+|peptidase-M14
MQRIRRVCLLVALGLAPALMAQPLQSPGEFLGYPPGARFTPHHRVVDYFEYVARTSPRVQLVQYGETYEGRPLLLAIISLPENLARIETLREDNLRRAGRLPGTPDPDGPVFVWLSYNVHGNEAVSTEAALLTLYALAHPDSQRTGAWLQHAVVLLDPCLNPDGRERYVQWYHRMLGVGPDPDPVAREHHEPWPGGRTNHYYFDLNRDWAWGTQQETQARLAVYHRWMPQIHVDFHEQGVDEPYYFAPAARPIHPLITDWQRALQDTIGRNHARYFDADGRLYFTREVFDLFYPGYGDTWPTFNGAIGMTYEQGGGGRAGLAIRTAEGDTLTLAERIRNHYTTGLSTIETAVRQRRTLLDRFARYFAEAQTQPAGRYRAFLIRGDAHPDQLAALTALLDRQGIRYGTLARTRTVEGLDYATGTRQRVEARPGDLVVSAYQPAGTLARVLFDPDPVLPDSLTYDITSWALPYAFGLEAYALSERLEPDRPGWARPTPTPPSEAQPYAYLVRWGGLDAARFLADVLRQGVKVRVTEVPLTLNGRRFEAGTLILTRAGSEHLGARFDRIVREAADRWHQQLYTTRTGFVDEGPDLGSARVRFLRKPRVYLLAGPPASAYAVGEVWHFFEQVLHYPITLVERDELDELLLDEGDVLILPHGFYNVREMPLESLLEGVRRGARLIALEGALDLLAGQQGVGLKRRQQEDSSEQDTAARPRRYAMREREAISDQVPGAIYRVQLDPTHPLAFGLARYFTLKRSTRAYELLEDGWNVAWLEDGRPRSGFAGYRAVERLRETLVVGTQRLGRGTLVFFVDDPLFRGFWHAGQLLFANAVFFGE
>NC_015966.1|WP_014065808.1|70973_72479_-|F0F1-ATP-synthase-subunit-beta
MEIKTDQAVGRVVQIIGPVVDVEFPEGQLPEIYDALVITLEDGSELVLEVEQHLGENRVRAIAMDSTDGLTRGTPVRNLDRPISVPTGTEIRGRLFNVVGQAIDGLPQPKAEGYRPIHAPAPPFEELATRVEMLETGIKVIDLIQPVMRGGKVGLFGGAGVGKTVLIMELINNIAKAHEGLSVFAGVGERTREGNDLLREMLESKVIRYGDAFLESMKAGGWDLSKVDFEELKKSQATLVFGQMNEPPGARARVALTGLAIAEYFRDLGGRDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGELQERITSTKHGAITSFQAIYVPADDLTDPAPATTFAHLDATTVLSRQLAAQGIYPAVDPLESTSRILDPNIVGEEHYRVAQEVKQILQRYKELQDIIAILGMDELSEEDKLVVHRARRVQRFLSQPFFVAEQFTGIPGKYVKIEDTVRGFRMILDGELDHLPERAFLLRGTIEEVIEAGEKMLKEAEA
>NC_015966.1|WP_014065819.1|87598_88192_+|MarC-family-protein
MNAYLETFLPLFVAINLPGILPFFISMTEGLSAADRRRLLVRAVATAFVVAVLILFAGQLIFETLGITLNDLRVGGGLILLVLSITDLVFADYRRRDPRDGADAADVGVVPLGIPLIIGPAAITTILVAQQTYGYLPTLVSLVANLLLVTVAFAAGPWVIRKLGPVAVRAIAKVASLFLAAIAVAMIRAGVAGMLAG
>NC_015966.1|WP_012842604.1|88272_88590_+|hypothetical-protein
MALKTLDIDALAAKTGNLYETVAILSKRARQIATQMKQELDEKLSYFEGLGLEDDPRHQEEQRRISIEYELKPEPTEIAVEEFLRDEIYYRDASKERSEEEEELR
>NC_015966.1|WP_155815957.1|88670_91100_-|glycoside-hydrolase-family-95-protein
MKGMGLALVAGPYWLRRALVQPSALSSPFVEARIPERGMYSLQPAARWEEALVAGNGTLGILVYGDPLNERIIFNHELLYEPLRDERVPPPNLAPYLPRIRALMLEGRYREAVAYSLEMARREGWPGLLWTDPYHPAFALVLEMPTETPTEYLRHTAFDTGEIGVFWRTATDTYTRRAFVSRTDGVVVLELSAEAGPLPDLTLHLEVQDVRPPEQREGYHPPEITAAPGWLRYRCAYVHTRRGYEGLVRVEAEGGTQTVRDGRLHVRGARRVLLLVRVWPLDDVAASRLAEEQAALAALPADYDLLFAPHAAAHGALFRRMTLDLEAGDDRRKSSETLLAEQRARETILPALLEKLFDMGRYVLISSCGHWPPNLVALWTGEWRPPWSGDFTLDANLNLQMAAASIGAVPEAVASLTRLLEGLLDDWRDNARRLYGCEGVLSGSRTDGRCGWHTHFNADYPLHFWTAGAGWLAQPLYEYAEVYGDEAFVREHLIPYLKEVVRFYETFLTVTDAEGHVVFVPSYSPENRPGNLDTPGSINATMDIAVCREVLSTLIALCEARGLEADSLPRWKALLDRLPPYLINEDGALKEWAHPDLADNYNHRHLSHLYPVWPGHEITPEATPELFEAARRAAYLRGHENDSAHGLVHLALIGARLKDPELAYRSLRDLIRNGYLLPSLFSLHYPGNVYNADLINSLPAIVIEMLLYSRPGLLELLPAVDERLPRGTLHGARARGRLRVERLRWDLPARHVELALVSDTDRTLTLRVRRGIAELQATEGPTPERTSATDATLQLAARTPATLQIRLAG
>NC_015966.1|WP_014065821.1|91185_92184_-|voltage-dependent-potassium-channel-subunit-beta
MEYRHLGRSGLKVSALSFGAWVTFGDQIDEGLAEECMHAAYEAGVNFFDNAEAYAGGKAEIMMGNILKRSGWKRSDLVISTKIFWGGKGPNDVGLSRKHIIEGTKAALERLQLDYVDLIFCHRPDPETPIEETVWAMNYVLDQGWAFYWGTSEWSAEQIRYAYEFARREHLIPPTMEQPQYNMFHRVRVEREYAPLYRDYGLGLTTWSPLASGILTGKYNEGIPEGSRMSLPGYEWLRKRLESEEGRRQIEKVRRLMPIAEELGCTMAQLAIAWCLKNPHVSTVITGASRPEQVQENMKALEVARRLTPEVMERIEAILENRPEPEINWRER
>NC_015966.1|WP_014065822.1|92250_93189_-|hypothetical-protein
MQPTQPPMAELPIHTVLSEAEARARAAAHEARLRPVLDPYLAARRRGAKQPVMDFLFEYYTFRPSRLLRWRPGLGVAVQGTDARRWLEDPDFVETPEGVTVDPARFPAHRIPSLRWVVTLLERTAARRPHLGCCGMHEWAMVYRTERPRHAHVPLRMDPDTLAAFVESHPITCTHFDAFRFFTEAARPLNRFQPTRDTIHELEQPGCLHANMDLYRWAYKFYPWVGSDLIADAFLLACRIRTLDMQASPYDLRAYGLEPIPIETPEGRRRYRALQEQFYREAQPIRRRLLQTLRTLLELAVTNAPTPADGVA
>NC_015966.1|WP_014065823.1|93291_93474_+|hypothetical-protein
MKRVLRAMLLSALATGAFAWVLSRLHPRPEPATVRPGEVDADELPPEAQERLLEELDRLL
>NC_015966.1|WP_014065824.1|93589_96355_+|insulinase-family-protein
MNLLRRLSAGLLLLLCTMPALAQTEEATDLPVEIPYEKFVLDNGLTLIVSPDHKAPIVAVNIWYHVGSKNEKPGRTGFAHLFEHLMFNGSEHFNDDWFQALERVGATDLNGTTNRDRTNYFQTVPVNALDLVLWLESDRMGHLLGAIDQAKLDEQRGVVQNEKRQGENQPYGKVWNIIAEHTYPEGHPYSWPVIGYMEDLDAATLEDVHEWFKTYYGPNNATIVIAGDIDPQTALEKVKKYFGSIPPGPPLAKPKAWVAKRTGEQRMTMEDRVPQARLYKVWNVPEWGHPERDYLDLAADVLASGKTSRLYRRLVYTDQIATDVSAFVYTGEIGSQFMIIATARPGVPLAQVEQAVDEELARFLEEGPTADELERVKADFIAGFIRGVERIGGFGGKSDILAQYEVFGGDPGLYKVTLRRVQQATPAQVLEAARKWLSDGVFVLEVHPYPKLQASGEDVDRSQLPPVGTPPEVSFPEVQQATLSNGLKVLLVERHAVPVVNFQLILDAGYAADQFARPGTATLAMNMLDEGTTSRTALEISDELDRLGARLSTGSDLDVSTVYFSALRDKLDPSLELFADVVLHPAFPEADFQRLKQQQLVAIQREQVSPVQMALRVFPRLLYGEGHAYGLPLTGSGTIESVQQITRDDLVRFHQTWFKPNHATLVVVGDITMDELLPKLERLFAEWKPGDVPQKNIQDVPQKDRSVVYLIDRPGSEQSIIFAGHVAPPEANPRELAIKAMNTVLGGAFTSRINMNLREDKHWSYGARSMLMSARGPRPFIVYAPVQTDKTAPAMLEIKKELDGIVSGQKPITPEELDKVQRNLTLRLPGRWETANAILDDLSYVVQFGWPLDYWRTYPDAVRALTLEDVNAAAREVLHPDRLVWVVVGDRSRIEDEIRQLELGPVYLIDTEGNLLASLSE
>NC_015966.1|WP_012842611.1|96455_97241_+|membrane-protein
MSLWARFKRWIRSIFGGAISALEDPRLILEQNIRELNDQIPKMNENIATVKANVLLLQKEVRRNEQEIERLVARIKAAIQAGRDDIAQQYAIQLQKAKETLARTKEQLQYAEAAYEKALQVKQAFLREKERKIQEAKEALRAHERAKWQAKVADALEQFEVGGLDQTHEEMVQRLREETARSEARLELALDSVDADALKIEADAEALRAAELVRQFKLEMGLLEPEQKPALESPAREAEQEAPEQARETEETKTIGRQRTR
>NC_015966.1|WP_012842612.1|97242_97650_+|hypothetical-protein
MRPEDYQRLKEAEKEHLRALRRLKEAVRLLRRRRAIDEALARLERQTEATLAAHDEALERLALETAYQEARLELALEGHEPPPDDALDPERTRRRAQELLRQLRDESETSAAADSSAPAEARTEKTLGRLRPPGS
>NC_015966.1|WP_012842613.1|97649_98567_+|hypothetical-protein
METTGMNDRPINYTREAFLHPWNLTFLIAALVTALGISFTDSPDWLFDAVLLFTTALELLYLGIMPRQERFRRAVRARRAAEHARPPSQKELFQLLSRSSQRRYVRLRNLEKQIRANYQKLSYASQGLLESHLQKIDELLRSYLNLLYQKERYEFYLAQTSEDELVEALQALQEDMADDAPRVRAIKERRRRILEQRLARIKKVRENLEIIEAQLDTIDDVIRYIHEQSLTLRNPEEITFQLDTLLSEVEETEAAVAEIEDVFASPSALLGELSAELEPPRMESEATEPSEKTPPEAVRRQRQRS

Crispr_ID: NC_015966_2

• CRISPR_ID: NC_015966_2
• CRISPR_location: 609528-609636
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_015966_2

Consensus_repeat	Method
AGCGGAGTGCCGTCTCGGGTGACGCCACT	CRISPRCasFinder

spacers of NC_015966_2

>2.1|609557|51|NC_015966|CRISPRCasFinder
CCGGCTGGCGCCTTCGTGGCGTACTACCAGCACGCTCGTAGTCAGGCACGG

CRISPR arrays and Neighbor proteins around NC_015966_2

CRISPR arrays

The CRISPR arrays of NC_015966_2

>merge|NC_015966|2|609528-609636|CRISPRCasFinder
AGCGGAGTGCCGTCTCGGGTGACGCCACTCCGGCTGGCGCCTTCGTGGCGTACTACCAGCACGCTCGTAGTCAGGCACGGAGCGGAGTGCCGTCTCGGGTGGCGCCACT

>NC_015966|2|2|609528-609636|CRISPRCasFinder
AGCGGAGTGCCGTCTCGGGTGACGCCACT	CCGGCTGGCGCCTTCGTGGCGTACTACCAGCACGCTCGTAGTCAGGCACGG
AGCGGAGTGCCGTCTCGGGTGGCGCCACT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_043760798.1|591636_593805_+|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319849
NC_015966.1|WP_014066217.1|597849_598098_-|UPF0175-family-protein	unknown	unknown	gnl|CDD|377095
NC_015966.1|WP_012844967.1|599354_600467_+|transcription-termination-factor-Rho	unknown	unknown	gnl|CDD|237150
NC_015966.1|WP_012843048.1|617375_617771_-|DNA-binding-protein	unknown	unknown	gnl|CDD|370129
NC_015966.1|WP_014066221.1|602814_607917_+|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|271215
NC_015966.1|WP_012843037.1|593805_594795_-|hypothetical-protein	unknown	unknown	gnl|CDD|225829
NC_015966.1|WP_014066229.1|620201_620846_-|sulfoxide-reductase-heme-binding-subunit-YedZ	unknown	unknown	gnl|CDD|235452
NC_015966.1|WP_014066224.1|613073_613943_+|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl|CDD|224238
NC_015966.1|WP_014066226.1|614380_615286_-|KaiC-domain-containing-protein	unknown	unknown	gnl|CDD|274831
NC_015966.1|WP_014066228.1|617947_620212_+|beta-glucosidase-BglX	unknown	unknown	gnl|CDD|185053
NC_015966.1|WP_014066225.1|614006_614378_-|hypothetical-protein	unknown	unknown	gnl|CDD|163591
NC_015966.1|WP_014066223.1|610676_613049_+|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl|CDD|224446
NC_015966.1|WP_014066215.1|595041_597069_+|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|224699
NC_015966.1|WP_012843042.1|610121_610637_+|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|224991
NC_015966.1|WP_014066222.1|608012_609188_+|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|260084
NC_015966.1|WP_081472063.1|601715_602255_+|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|238509
NC_015966.1|WP_014066219.1|598211_599039_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NC_015966.1|WP_014066220.1|600525_601263_+|JAB-domain-containing-protein	unknown	unknown	gnl|CDD|178801
NC_015966.1|WP_014066227.1|615556_616651_-|putative-methyltransferase	unknown	unknown	gnl|CDD|224484
NC_015966.1|WP_029933162.1|616861_617359_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_043760798.1|591636_593805_+|cadmium-translocating-P-type-ATPase	gnl|CDD|319849	cd07551, P-type_ATPase_HM_ZosA_PfeT-like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis ZosA/PfeT which transports copper, and perhaps zinc under oxidative stress, and perhaps ferrous iron. Bacillus subtilis ZosA/PfeT (previously known as YkvW) transports copper, it may also transport zinc under oxidative stress and may also be involved in ferrous iron efflux. ZosA/PfeT is expressed under the regulation of the peroxide-sensing repressor PerR. It is involved in competence development. Disruption of the zosA/pfeT gene results in low transformability. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_015966.1|WP_014066217.1|597849_598098_-|UPF0175-family-protein	gnl|CDD|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	3.88562e-21
NC_015966.1|WP_012844967.1|599354_600467_+|transcription-termination-factor-Rho	gnl|CDD|237150	PRK12608, PRK12608, transcription termination factor Rho; Provisional.	0
NC_015966.1|WP_012843048.1|617375_617771_-|DNA-binding-protein	gnl|CDD|370129	pfam08797, HIRAN, HIRAN domain. The HIRAN domain (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. The HIRAN domain is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this domain functions as a DNA-binding domain that probably recognizes features associated with damaged DNA or stalled replication forks.	1.98994e-17
NC_015966.1|WP_014066221.1|602814_607917_+|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|271215	cd14256, Dockerin_I, Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.	3.4616e-16
NC_015966.1|WP_012843037.1|593805_594795_-|hypothetical-protein	gnl|CDD|225829	COG3292, COG3292, Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms].	2.83912e-07
NC_015966.1|WP_014066229.1|620201_620846_-|sulfoxide-reductase-heme-binding-subunit-YedZ	gnl|CDD|235452	PRK05419, PRK05419, protein-methionine-sulfoxide reductase heme-binding subunit MsrQ.	3.69793e-72
NC_015966.1|WP_014066224.1|613073_613943_+|xanthine-dehydrogenase-family-protein-subunit-M	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	6.11332e-86
NC_015966.1|WP_014066226.1|614380_615286_-|KaiC-domain-containing-protein	gnl|CDD|274831	TIGR03878, thermo_KaiC_2, KaiC domain protein, AF_0795 family. This KaiC domain-containing protein family occurs sporadically across a broad taxonomic range (Euryarchaeota, Aquificae, Dictyoglomi, Epsilonproteobacteria, and Firmicutes), but exclusively in thermophiles.	2.37394e-164
NC_015966.1|WP_014066228.1|617947_620212_+|beta-glucosidase-BglX	gnl|CDD|185053	PRK15098, PRK15098, beta-glucosidase BglX.	0
NC_015966.1|WP_014066225.1|614006_614378_-|hypothetical-protein	gnl|CDD|163591	TIGR03879, Uncharacterized_protein_MJ1053, probable regulatory domain. This model describes a common domain shared by two different families of proteins, each of which occurs regularly next to its corresponding partner family, a probable regulatory with homology to KaiC. By implication, this protein family likely is also involved in sensory transduction and/or regulation.	4.85465e-14
NC_015966.1|WP_014066223.1|610676_613049_+|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl|CDD|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	0
NC_015966.1|WP_014066215.1|595041_597069_+|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	3.08705e-83
NC_015966.1|WP_012843042.1|610121_610637_+|(2Fe-2S)-binding-protein	gnl|CDD|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	2.13064e-83
NC_015966.1|WP_014066222.1|608012_609188_+|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|260084	cd08547, Type_II_cohesin, Type II cohesin domain, interaction partner of dockerin. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type II cohesins; their interactions with dockerin mediate attachment of the cellulosome complex to the bacterial cell wall.	1.49137e-09
NC_015966.1|WP_081472063.1|601715_602255_+|DUF559-domain-containing-protein	gnl|CDD|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	2.00103e-18
NC_015966.1|WP_014066219.1|598211_599039_-|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.43967e-29
NC_015966.1|WP_014066220.1|600525_601263_+|JAB-domain-containing-protein	gnl|CDD|178801	PRK00024, PRK00024, DNA repair protein RadC.	3.01015e-101
NC_015966.1|WP_014066227.1|615556_616651_-|putative-methyltransferase	gnl|CDD|224484	COG1568, COG1568, Predicted methyltransferases [General function prediction only].	6.26164e-119

Protein sequences

>NC_015966.1|WP_014066222.1|608012_609188_+|T9SS-type-A-sorting-domain-containing-protein
MWNWNSLTKRNLLAAALVCLLAGSAAAQTVSVGPIAGAPGDTVAVPVYISDSPALSGLRVSFKLDDPSVATLYKVTTEGTFVSDLLASGGLSDKSDTAYAAVAASAVEVSRDTLVVLHFILSDQTAATEGTLTVKLSVGDNPPQSQTHELETIAVASDVAVTVAADVLLTDQANTVALEIGDVSGLDVRGYQFDLVYDPAMIEITGADRSGTLSESGQFAANAVSEGRFRVVWANTAALSGSGTLLNLNVNALQKGAVLIRFENVKFVDASGEVVPVATQNKLILTSTTANEPAGALPSEFALRSVYPNPFREALQVRVDLPRPAEVEVVLYDVLGRQVWARRLGTLPAGSDRAIQVDGSTLSAGIYFLRVRATADNGTTFERVARVVHVK
>NC_015966.1|WP_014066221.1|602814_607917_+|T9SS-type-A-sorting-domain-containing-protein
MYGTVTLTRLGTTKPNQEVRSMNTVQRLSAALLAVFLFLLAGAGGALAQTLVGPGGNYATLAGAISAIEDGSLTGDVTLQIIGNLTNEPAEIVFDVAGGATSVTIIAQDANPYTVQTILNIGVSIPVQFGNGTDDLNLTLNGLTVNSGTHTIAAKANLTVTGNLTVNGTLTNNGTLTVNGASAVSGSLTVDAEATVDLGGNTLTVANGATLTNDGDIVNGTVATPSGTTATTSTINGSGNFPNVTIGSNNTATFGGSPTINGSLTVDGTVNGAGTVTLAGDNTTHTISGTFNPTMLVDATGVTINGSTASGAASTIGTFTVNNNGSAVIQDIKQITSVNVNTGASLQATLAGSSGGTITTNFQVQQGATASLGNANVGGTLQVTGALTQPSSLTLIGDVSVTGATTIGSYATLDIGTHTLTLGDDISVDNTASLAGSGTFKLTGSTSGHDFAGKSIANLLVAGAAAIGNDVTVTNSLTVDDGNNTAGEGLFTILTGYTVTVSGTVTLKDDFAANTGTLNVVGTTIQAPFATGLTAVQLPAVTIDAPGGVTFASSTSTNGTFQVQGAFTHKQGEISLGDNNLEFQGNYTYQGGSYMAGDGHVIWNSAGTFDANDNTVSFPNLTVSQGLTAGDDDSIEIQNTLVANAAISVDGDNDGVGKVKILDGASVTYGVDNPLGTDADDVELGNDLHVTYTATAATNVELPELPASVATLTAKGTGVTLTVNKNVTVNQKVTADGATITVNDGGSSVVSLAVASGGTIEVTNNGSFNVPDNDKISVTDYHLVYSDDVGTTYTAGPELDTLATILSLTVKDTDTGTAGTPKVQLPNADVTVVDLVLDNGVVYINTTAQSRTLTVTGNATFIGVGNVEAGAGNPGTLAFAGSSAQTFTVPSGGLKFAQDSPDAVHLQINNAAGVTLAGGNLTMGAGGNLILTEGLLKTGESNWIDLDDVAEVVRTNGAIQGNVRTDTLSAISGIASVSFDHLGTYTNGTAYLRKVKISADDFDDFAAQNVTELIVGYFDGDPGGSNGFPLMDGSLEITRYPNFYWRIQSGDGPIQPTNLSYDLEFDVEGYADFVAENVNNMRLIRRAPGSLSNPWMLIQGTYDNENDASPSNDHPIVRVAGATGVIRSAGQIVTFGLENNMVAVAPDAMVLNEGMTSKLTLSPDVFSGGAPLLNAPPSYTYTVSSSDDNVATATTDGDTLVVTAVGAGSATITIEATDRLGTSTSTTLTVNVNPDLVAQGTIANRGVNVDTTIWIAPLGSYFAGGTPPYSFAAASSADSVATASVSNDTLYVTGVAQGMATITVTATDSLGDTAQQSFTVAVNTGLAAADTIQAFPLVVGQDTSFTLSNYFVGGTPPVSFAAASSDTAVAKASVSGDVLTVSAVGAGMATITVTATDSVGATADFSFEVSVLLASGDVNGDGTFDQTDVVLVLQAIVGKTTLSPAQQLAADINGDGAVDVADAVLMLQQLVGSGAGKRSAQAVRLDAVSAQVAWGEARFSGGTVELPIVLKEAQHVYGVELELPLPETVTFEAIATSLPEGWLSVSHFDAESRVLRVALAGLTPASGEILRLRLNAGETKTLAGLKATVRLNAKETAELAPVTVQELPTHYALEASYPNPFRTTTTIKYQLPEEAHVTLVVYDIQGRVVARLVDAVQKAGYHTVTWDGRTESGAPAAAGLYLYRLQAGSFSAVQKVMLVR
>NC_015966.1|WP_081472063.1|601715_602255_+|DUF559-domain-containing-protein
MPVDRSGARYRRRLRKQATPAERRLGACLRKRRLKGRRFRRQHSIGTYVVDSYCPSERLGVVHEDVARACYDAEREAHLRTRGLRVLRFENRQVPEAIRQAFRGRYAGSGRVSRWRQSRDPLRRFATAPSGRGSGREDRRGAAPGVGGRGYRRWFLFGRAVHGRAPASGRGSPLCPLDL
>NC_015966.1|WP_014066220.1|600525_601263_+|JAB-domain-containing-protein
MSREAHGSGEPPLRYQVPINQWDEADRPREKLMRRGPSALSDAELIALIFGSGTRTKQGSISAVQLGQALLRAYGSLYALAQRDLKELTRVAGVGPAKAVQLVAAFEIGRRVEAQRPGRRVQVRTPADVAACYGPLLRDLKREVFKIVLLNTANYIIADYTISEGGLAASIVEPRAVFQRAILDNAAGIICLHNHPSGNPEPSAEDIRITRQLVEAGRLLGIPVHDHIIIAGTTYTSLAERGLMG
>NC_015966.1|WP_012844967.1|599354_600467_+|transcription-termination-factor-Rho
MSEQTFRGMLELIGDKKFGFVREFRPDLPKGKNDPFVPPPVIRRYNLRDGVLIEGTLRPGRKGDMQVDEIHSIMGVSPEEWAKTEDFESGQIVYPDEKFNLVTGPTDYAMRVVDLAAPIGKGQRALIVAPPRAGKTVLLKQIAAGIAKNHPEVKLVALLVDERPEEVTDFRRSTPAIVFASSNDREEDNHIRVSTLALEFAKRLVELKHDVVLLLDSLTRLGRTFNLYVESSGRTLSGGLDARALQIPRRIFGAARNIEGGGSLTIIATALIETGSRMDEVIFEEFKGTGNAEIVLDREMADKRIFPAINLRKSGTRNEERLIGDRIEQYHRLFRALNSRPPIEAMQALLRHMQQTQSNEELLNSLVPVE
>NC_015966.1|WP_014066219.1|598211_599039_-|alpha/beta-hydrolase
MQTAEVQKTSANPTAWLERLHLEVQGPEDGPPVLLLHGWGSSARLMAPIAEALADRYRVFNVDLPGHGLTPPPPEPWGVAEHAALVAELIRRHIGRPVVLVGHSNGGRIGLYLASEPKGPELLRALVLISPSGMRPRRPWHYYVRATLARLLKAPFQVLPQPLREPALDWLRHTVVWKALGSSDYRRLEGVMRETFVRIVNTYVEDRLDRIRIPVLVFWGERDRAVGRAQMERLVQALPDAGLIVLKNAGHYGYLDDPDTFIAATRYFLEHLPER
>NC_015966.1|WP_014066217.1|597849_598098_-|UPF0175-family-protein
MDVQVIFPEELLVALKEDRESFRKKVLLYTLGKLYEQGRISAGLGARILGCDRQEFYRLLSEHGFSVIDYPEEELAREANSE
>NC_015966.1|WP_014066215.1|595041_597069_+|T9SS-type-A-sorting-domain-containing-protein
MRRTLQWALMLLLCLPASLTAQTRKHVILYIGDGHGIAPRTATRMALGQGRPGSRFSDDPNFHLLAQDRLRYNAMVTTHSLNSWITDSAPGASVYAVGKRGKIDNEFISLDPETHEPLETVLEAAKKAGYAVGLVTTTRVTHATPAAFAAHIWNRDLEDYIAAQYLSSSQEEYEAIFNAGPGYDPARDWVLPEPKVGVEIDVMLGGGARHFLPRNNPDVNGNATVRDRNGQPITDGNGQPVVLSGRRSDNVDLIEIAKDRGYVYVNSRDALLGILDRLDEFSPENDAKLLGLFSSSHRSYEAERQQLYPWEPALWEMTMVAIEVLKRKSDKGFFLVVEGGRIDHLEHANAGGIGYEGDRYTVVADVEAIIADDVYGGGTDRLAGVYGSDYMIKEVLDFDYAIEEGLTFMNDAAGQTLILSTSDHECGGFTVVGLHDAEDAQGNGTLIRTYARQPEKTDGQFTPVPENIDRGDDEIGGWFPEYELVEFQGKLWPEPAGPNARRIVIAYGSNPLVNGNGGTIGTTPGNHTPQDVWVGADDNVDGAFASRITGRGLLDNTDLFPIMRDFLGVTTTSNERLPDEKRSGLGAVEAYPNPFGEKLAVTLAIDRPQTVSLEVYNALGQRVRVLQPSAQLTPGTHTIAWDGRDDTGASVASGLYLVVARSGEQVVSRQVVRIR
>NC_015966.1|WP_012843037.1|593805_594795_-|hypothetical-protein
MTPRALLWMVLLVVAGCRTTQPVTVTLPASLPEPPTVLLPWYDGWLLGGGKVLWWLRDKRPIHRWILPAAVQGGVVDPEGVLWLGTGAGLVRLTAPTAQPERVPLPALNRFPSVTTLTLDAQQRLWVGTAQHGVFLRADTSWRPVLAAAPVYALATTTDGTVWVGTGIGLFRQTSDGWLVYSEEGTANHGLPDNIVERLVALPEGLWVIMSEAVSFFPVDEVDHPVEFAYLGHPGNRIHDVVDLPESGYLLATDDGLVWLRELPHFDTHGGLRELRVMEYDLARPLSPASLALPDEPITRLDRRGNWLYLAGPSGLFRRLLPPAALAHR
>NC_015966.1|WP_043760798.1|591636_593805_+|cadmium-translocating-P-type-ATPase
MAAAFEERPARCTLHVQGQGGRSCETCALALERRLQALPGVRQARVSFRGGVLHVIYDAAQTTPEELARVVERFGVRTLPPKPAVSWRIWLEGTRREALFVALTLAGLVTGWLAGRLGAPLVAAVAYGVAYVFGGWDGLRNGIGALRHRTVDVDLLMVLAALGALVIGAPAEGATLLFLFSLSNLLQHYAIGRSRRAIQALMELRPDRARVLREGQEVEVPVEEVRVGEVFVLRPGDRVPLDGVIVRGESALDESSITGESMPVDKGPGQEVFAGTINTTGSLEVRVTRPASASTLARMIELVEQAQSEKAVTQRLIDRLEQPYALGVLAMTALAIVIPVAFLNEPFARAFYRAMTLMVAASPCAVVISTPAAVLSAIAAGARRGVLFKGGVYVEALARVRAIAFDKTGTLTEGRTRLVQVGARPSAGLSEDELLRLAAAVQQRSEHHLARATVAAARERGLTISEAEGFQAVVGKGVRAVVEGATLHVGNLRYFEAAWQAADGFDEGRAAVEALARQGRTAVLVARERDGQREVLGWLAFADRLRPGAAETIRRLRELGVAHVALLTGDNRHVAEAIGREAGVDAVHAELLPAQKVAHVKALVDRYGAAAMVGDGVNDAPALAAATVGIAMGGAGTDVALETADVVLMRDDLAELPYVLALSRATRRTLLVNFAIAFGMMGLMIGAILLQGLPLPLAVVGHEGSTVLVSLNGLRLLRFRAS
>NC_015966.1|WP_012843042.1|610121_610637_+|(2Fe-2S)-binding-protein
MRHTIQVTVNGQTHRVEVEPRLLLVELIRDVLGLTGTHVGCDTSQCGACTVHVNGEAVKSCTMFAVQADGCEITTIEGLARDGALHPLQEGFWQEHGLQCGFCTPGIIMAAADLLRRNPDPSEEEIRHALEGNFCRCTGYHNIVRAIQYAAARMRGEAVVPRGEAASTGAS
>NC_015966.1|WP_014066223.1|610676_613049_+|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MEARGYIGAPIRRVEDRRFVTGRGRYTDDIVLPGMLYAWIVRSPHAHARIRAIRTEKARQHPGVVAVFTGKDLLDDGVGSLPTGWQIGPDMKEPPHYALAVDKVRYVGDGVAVVIAETKAAARDAAELVEVDYEELPAVVDAAEALKEGAPLVHDDAPGNLCYVWELGDREATDRALAAAHHVTKLEFVNQRLIPNAIEPRSAIGHYDPGRDELTLYTSSQNPHLIRLLLSAFVLKIPEHKVRVISPDVGGGFGSKIFHYPEEVICAWSSRKLGRPVKWTAVRSESFVSDAHGRDHITTAEMGFDRDGRIVGLRVRTIANLGAYLSTFAPGVPTWLYGTLLAGQYKTPHIHVEVKGVFTNTTPVDAYRGAGRPEATYVVERLVELGAHELGIDPAELRRRNFIQPDEFPYQTPVVLQYDSGNYEGALNKALEMADYWKLREEQKRAREQGRLIGIGLSCYIEACGLAPSKVAGAIGVRAGLYESAAIRVMPTGKVQVFTGTHSHGQGHETTFAQIVAHELGIPLEDVEVIHGDTAEIPFGMGTYGSRSLATGGSAIYRALEKVKAKARKIAAHKLEVAEEDLEFRNGQFIVKGTDRAIGFGDIALTAYVPHDYPEGLEPGLEENAFYDPANFTFPFGAHLSVVEVDPETGRVKLLRYIAVDDVGRIINPMIVEGQIHGGVAQGVGQALLEGAVYDRSSGQLLTGSLLDYALPRADDLPSFEVGHQETPCPHNPLGAKGAGEAGTIAATACVVNAVVDALYHLGVRDIRMPLTPERVWRAMRGLPTDGHAS
>NC_015966.1|WP_014066224.1|613073_613943_+|xanthine-dehydrogenase-family-protein-subunit-M
MIPQTFAYRKARTIDEALALLREHGDEAKVLAGGHSLIPLMKLRLSTPELLIDIGGIRELTEIRERDGRLELGALVTHRTIEFSELLRQKCPVLPEAAAQIGDPQVRNKGTIGGSLAHADPAADYPAVVLALDAEIEATGPDGRRTIPARDFFQGLFTTALRPGELLTRVRVPVMPPRSGAAYLKFPNPASRYAVVGVAAFVKLAPDDTCAEVRIGITGAAAAAFRATEAEKRLVGKTVDERTLAAALEDMVDPDDLLSDLAASAEYRAHLCHVLARRALRQAFERARG
>NC_015966.1|WP_014066225.1|614006_614378_-|hypothetical-protein
MPVEVTPQPVDLDQRALQVFLKAIELAGGPRGLLERKRLTWLPSLMEAAYAVVLEAEHYRSVDEIARFLGLSTAATRNLLRASTEAVRERLEQEEPSEHNVHIAGGLARLAYEALQREAARAG
>NC_015966.1|WP_014066226.1|614380_615286_-|KaiC-domain-containing-protein
MAGAVSREAGPLVEAIVSLRHAAAAAPPLEGVPTGVEGLDELFFTTEWREGRPVRKPLGGIPRYAVLQVTGVADTGKSLLVEQFAVEQARRGQVCLFLTTESPAPFVAMGLRTRAAAMGADWHALEDRIVLVDAATHTILTQDLPTLFNTLAHAIKTYHVRAVVIDSITGLYEAREMLARDVVRPIFTFLKKWHQTALLVSQKRSGHELLTAEAAGGYAVGHILDGTLVLAKQPITSAQQARLYRVPIGETVRLFRIDGCRLCGHDTSTHLLEITPTGLVRIGPSLQTFHQEASVEPNYQT
>NC_015966.1|WP_014066227.1|615556_616651_-|putative-methyltransferase
MPHTKTFPETLAVELRGRLLETVRQQVPVPFTERDAERALAALLTTDNLWEAIRLSRVPLRVLSVFWHQLIAEGLLEAHDGALRLTESGQALAQALGVAPVREATCVHCEGRSVDYRTLPGDVVERFAEICRHRPEAIQDYDQGFVTEATTLARIAFAWHRGDLEGKQLLVLGDDDLMSIAAALTGAPAYVLAVDIDDRLIRFINDVARREGLDRLEAVRYDLREPLPTSWLRKFDTFMSDPTESFLGFKTTIERGLLALRGPGCAGYFGLTHVESSYEKWAQIQRFLLDSGVVLTDLIDDFSAYVNWGYIESMRSWEWLPTHRLPERPWYYSALHRIELLRTPALENAAVEGDIFTDEEAATT
>NC_015966.1|WP_029933162.1|616861_617359_+|hypothetical-protein
MVVGIDSRRYTSDQATIWRWRWAFQHDFAARMDWTIKSFEEANHNPIVVVNGREGKAPLWMKARVGQPLVLDATGTRDPDGDALTYTWFVYPEAQTGRAFRPAARLEGDRIVPLPPRATLIGEHSPRVTVIPNLPGETHLILAVEDDGTPGLTAYRRVILDVQPE
>NC_015966.1|WP_012843048.1|617375_617771_-|DNA-binding-protein
MFTRRAFLKTLVALGLWPGVTDSGRRARSVVLLETWVAGFRYHQGPRVQHRLRVGQPLVLRREPANPYDDRAIALYTGDGVKLGYVPRVDNSVLATMLDQGVPLKAVITDVACEAPPWERVRFRIKMAWGG
>NC_015966.1|WP_014066228.1|617947_620212_+|beta-glucosidase-BglX
MRTLRLLTLSLLWSGWLLPAIAQVDRAREDSLIEALLARMTLEEKLGQLTLYNGGMAETGPVVREGEPDAIRRGRVGAVMNFFGAEAVCAMQRQAVEESRLGIPLLFALDVIHGFRTIFPVPLAEAATFDPALVEQAARVAAGEASAVGLNWTFAPMVDIARDARWGRIVEGSGEDPYLGAVMAAARVRGFQGRDLRDPTTILATAKHFAAYGAAEAGRDYNTVDVSERTLREVYLPPFEAAVRAGALSIMSAFNEIGGVPATADRWLLTDVLRHEWGFEGLVVSDYTSVWELLFHGIAADSAEVGRKALEAGVDMDMVSGIYVRKLAEEVRAGRLSEAVVDEAVRRVLRVKYRLGLFEDPYRYCRDASREQVLLSPAHRRLAREVARKAIVLLKNEGELLPLADTLQRVAVIGALANDSASVLGPWAAAGRPEDAVTILEGIRAALPGATVRYAPGYAEVPSGSFQEMVAAALSPDTSGFAEAEAVARWAEVVILVLGEHRELSGEAASRASVELPGVQLALARRLLALGRPVVVVLMNGRPLAIPELAALAPAIVEAWFLGTEMGHAVADVLLGKASPGGRLPVSFPRATGQEPLYYNHKPTGRPPRAEEKYTSKYVDVPWTPLYPFGYGLTYTTFAYDSLRLSRRRLGLDDTLEVVVSVTNTGRRRGEEVVQLYVRDEVASVTRPVKELKGFARVELAPGETKAVQFRLPVRALRFWGLEGGWVVEPGWFTLWVGPSSAEGLQARFEVVSP
>NC_015966.1|WP_014066229.1|620201_620846_-|sulfoxide-reductase-heme-binding-subunit-YedZ
MRRLTPWLNGLVWLGVAAPLLYLTWGLWMDRLGANPIQEITHQTGRWTLRFLLATLAITPLRRLTGWNGWIRWRRRLGLAAFFYASIHLLLYLWLDQFFDWGEIGRDILKRRFITVGLLAYGLMVPLAVTSTAGWIRRLGGRTWRRLHRLVYAIAVLGVLHYWWAVKFDWRPPLAYGLILLALFLLRLRRPRVGRIDATALPRRTAAPVGDPTD

Crispr_ID: NC_015966_3

• CRISPR_ID: NC_015966_3
• CRISPR_location: 707737-707843
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14u_CAS-V

Consensus repeat of NC_015966_3

Consensus_repeat	Method
GGCACGGAGCGTAGCGGAGTGCCGT	CRISPRCasFinder

spacers of NC_015966_3

>3.1|707762|57|NC_015966|CRISPRCasFinder
TTCGAAAAGCGTTATTCCGGCTGACGCTTCTGTGGTTCACCAACGCGCTTGTAGTCA

CRISPR arrays and Neighbor proteins around NC_015966_3

CRISPR arrays

The CRISPR arrays of NC_015966_3

>merge|NC_015966|3|707737-707843|CRISPRCasFinder
GGCACGGAGCGTAGCGGAGTGCCGTTTCGAAAAGCGTTATTCCGGCTGACGCTTCTGTGGTTCACCAACGCGCTTGTAGTCAGGCACGGAGCGTAGCGGAGTGCCGT

>NC_015966|3|3|707737-707843|CRISPRCasFinder
GGCACGGAGCGTAGCGGAGTGCCGT	TTCGAAAAGCGTTATTCCGGCTGACGCTTCTGTGGTTCACCAACGCGCTTGTAGTCA
GGCACGGAGCGTAGCGGAGTGCCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_014066296.1|709057_709747_+|hypothetical-protein	unknown	unknown	gnl|CDD|379325
NC_015966.1|WP_014066297.1|709755_711042_-|isocitrate-lyase	unknown	unknown	gnl|CDD|237893
NC_015966.1|WP_014066291.1|703573_704230_+|deoxyribonuclease-V	unknown	unknown	gnl|CDD|143472
NC_015966.1|WP_012843133.1|697730_697937_-|50S-ribosomal-protein-L35	unknown	unknown	gnl|CDD|234676
NC_015966.1|WP_029933155.1|700827_702804_+|carbohydrate-binding-family-9-domain-containing-protein	unknown	unknown	gnl|CDD|187676
NC_015966.1|WP_012843132.1|697362_697710_-|50S-ribosomal-protein-L20	unknown	unknown	gnl|CDD|179959
NC_015966.1|WP_014066289.1|698066_698609_-|translation-initiation-factor-IF-3	unknown	unknown	gnl|CDD|234582
NC_015966.1|WP_012844733.1|717029_717485_-|response-regulator	unknown	unknown	gnl|CDD|381150
NC_015966.1|WP_012844731.1|718819_719773_-|HDOD-domain-containing-protein	unknown	unknown	gnl|CDD|370050
NC_015966.1|WP_014066299.1|712732_714559_+|hypothetical-protein	unknown	unknown	gnl|CDD|270690
NC_015966.1|WP_014066300.1|715106_716936_-|Na+:solute-symporter	unknown	unknown	gnl|CDD|271371
NC_015966.1|WP_014066294.1|706945_707704_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_015966.1|WP_155815845.1|702719_703316_+|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014066298.1|711210_712728_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NC_015966.1|WP_012844735.1|714643_715063_-|co-chaperone-GroES	unknown	unknown	gnl|CDD|238197
NC_015966.1|WP_014066293.1|705972_706938_+|hypothetical-protein	unknown	unknown	gnl|CDD|224688
NC_015966.1|WP_043760328.1|698680_700669_-|threonine--tRNA-ligase	unknown	unknown	gnl|CDD|234752
NC_015966.1|WP_014066301.1|717670_718837_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	Cas14u_CAS-V	-	gnl|CDD|223747
NC_015966.1|WP_014066292.1|704722_705898_+|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|379051
NC_015966.1|WP_014066295.1|708186_709050_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|214621

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015966.1|WP_014066301.1|717670_718837_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	Cas14u_CAS-V	-	3.7e-47	156.2	3.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_014066296.1|709057_709747_+|hypothetical-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	0.00521981
NC_015966.1|WP_012844733.1|717029_717485_-|response-regulator	gnl|CDD|381150	cd19923, REC_CheY_CheY3, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY3 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY3, Escherichia coli CheY, and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	8.52678e-12
NC_015966.1|WP_014066291.1|703573_704230_+|deoxyribonuclease-V	gnl|CDD|143472	cd06559, Endonuclease_V, Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases. Endonuclease_V (EndoV) is an enzyme that can initiate repair of all possible deaminated DNA bases. EndoV cleaves the DNA strand containing lesions at the second phosphodiester bond 3' to the lesion using Mg2+ as a cofactor. EndoV homologs are conserved throughout all domains of life from bacteria to humans. EndoV is encoded by the nfi gene and nfi null mutant mice have a phenotype prone to cancer. The ability of endonuclease V to recognize mismatches and abnormal replicative DNA structures suggests that the enzyme plays an important role in DNA metabolism. The details of downstream processing for the EndoV pathway remain unknown.	7.84922e-110
NC_015966.1|WP_012843133.1|697730_697937_-|50S-ribosomal-protein-L35	gnl|CDD|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	3.03419e-22
NC_015966.1|WP_029933155.1|700827_702804_+|carbohydrate-binding-family-9-domain-containing-protein	gnl|CDD|187676	cd09618, CBM9_like_2, DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized subfamily are typically found at the N-terminus of longer proteins that lack additional annotation with domain footprints.	4.50277e-80
NC_015966.1|WP_012843132.1|697362_697710_-|50S-ribosomal-protein-L20	gnl|CDD|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	1.51809e-57
NC_015966.1|WP_014066289.1|698066_698609_-|translation-initiation-factor-IF-3	gnl|CDD|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	1.80146e-91
NC_015966.1|WP_012844731.1|718819_719773_-|HDOD-domain-containing-protein	gnl|CDD|370050	pfam08668, HDOD, HDOD domain.	1.43919e-43
NC_015966.1|WP_014066299.1|712732_714559_+|hypothetical-protein	gnl|CDD|270690	cd05120, APH_ChoK_like, Aminoglycoside 3'-phosphotransferase and Choline Kinase family. This family is composed of APH, ChoK, ethanolamine kinase (ETNK), macrolide 2'-phosphotransferase (MPH2'), an unusual homoserine kinase, and uncharacterized proteins with similarity to the N-terminal domain of acyl-CoA dehydrogenase 10 (ACAD10). The members of this family catalyze the transfer of the gamma-phosphoryl group from ATP (or CTP) to small molecule substrates such as aminoglycosides, macrolides, choline, ethanolamine, and homoserine. Phosphorylation of the antibiotics, aminoglycosides and macrolides, leads to their inactivation and to bacterial antibiotic resistance. Phosphorylation of choline, ethanolamine, and homoserine serves as precursors to the synthesis of important biological compounds, such as the major phospholipids, phosphatidylcholine and phosphatidylethanolamine and the amino acids, threonine, methionine, and isoleucine. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.16328e-05
NC_015966.1|WP_014066300.1|715106_716936_-|Na+:solute-symporter	gnl|CDD|271371	cd11477, SLC5sbd_u1, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	7.47452e-166
NC_015966.1|WP_014066294.1|706945_707704_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.00433257
NC_015966.1|WP_014066297.1|709755_711042_-|isocitrate-lyase	gnl|CDD|237893	PRK15063, PRK15063, isocitrate lyase; Provisional.	0
NC_015966.1|WP_014066298.1|711210_712728_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.95258e-15
NC_015966.1|WP_012844735.1|714643_715063_-|co-chaperone-GroES	gnl|CDD|238197	cd00320, cpn10, Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It forms heptameric rings with a dome-like structure, forming a lid to the large cavity of the tetradecameric cpn60 cylinder and thereby tightly regulating release and binding of proteins to the cpn60 surface.	8.94656e-18
NC_015966.1|WP_014066293.1|705972_706938_+|hypothetical-protein	gnl|CDD|224688	COG1774, COG1774, Uncharacterized homolog of PSP1 [Function unknown].	1.54749e-67
NC_015966.1|WP_043760328.1|698680_700669_-|threonine--tRNA-ligase	gnl|CDD|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0
NC_015966.1|WP_014066301.1|717670_718837_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.93905e-31
NC_015966.1|WP_014066292.1|704722_705898_+|DNA-polymerase-III-subunit-delta'	gnl|CDD|379051	pfam13177, DNA_pol3_delta2, DNA polymerase III, delta subunit. DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.	3.14514e-58
NC_015966.1|WP_014066295.1|708186_709050_+|VWA-domain-containing-protein	gnl|CDD|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	1.61054e-07

Protein sequences

>NC_015966.1|WP_014066294.1|706945_707704_+|tetratricopeptide-repeat-protein
MGSGKSRLLVVALWLLAAKVGQAQDGLWLAQVDSLWRQGAFEEALALLGDSLQRNPNAAELRWRRSRVRVELGLRAPDKERQRELYRLGLKDARAAIAADSLNSRAYVAAAIAAGRLALVSGPRAKVELARQIRAYIDRALALDPNGDIAYHLRGRWRYEVATLSFFERTLVRLIYGGLPDASLEEAAEDFRRALALRERVVHHLELGRTLLRLGDRETAIQELKRALALPPTDPDDTTYQEEARRLLARIR
>NC_015966.1|WP_014066293.1|705972_706938_+|hypothetical-protein
MACGSACVQGGGCGGGCASGNGCPSLHVFDWLSHLSGPYPTYDIVEVRFKGRRKGLYRNVDRMDLQAGDYVIVEADRGVHFGIVHLTGELVRLRVRAKGLDDDAEFPRIVRLATLDDIDRWEANKQQEIEAFYIAREAIERLGLPMKLVDAEWQFDHKKITFYFTADHRVDFRQLVRELARTFRTRVELRQIGARDEAARIGGIGSCGRELCCSTWLQEFKPVATQTAKIQNLPLNPARLSGQCGRLKCCLNYELEQYMAALKDFPPVDTPVETERGRGTVQKLDIFKRRVWIQYEDGNWEDMALEDVQPYLRPRTSAGKS
>NC_015966.1|WP_014066292.1|704722_705898_+|DNA-polymerase-III-subunit-delta'
MAWERIIGQERVVEALRRALAQQRVAHAYLFYGPDGTGKRAAALTFAQALQCERGGSDPCGQCVPCTKVRRLIHPDVQVMLPHPSDADPDDLYERLQRLAAEPYATVDYIRRPVLDDPTRASNKQAFYSVARINESLRRSVSFKPLEGRYRVAILIDADRMRVEAANAFLKLLEEPGPQTVFILTTSRPDHLLPTVRSRCQHLRFDPLPAEAIAQALVEREGVDEARAMVLARMADGSYSRALDLLENEVLQADREQALAFLRQAYRFHSEALVDLVEQLSTLGRERLKGLLQLMLGWVRDLVLFRTLGDGAELVNLDQQEAIRRFCQNLPEADLEGMARLLEEALELIERNVQPFLVLSVLAAALRDAMHGRAPERLVPALDDPLALGLV
>NC_015966.1|WP_014066291.1|703573_704230_+|deoxyribonuclease-V
MGLTPRFTHPWNLSPTEAQALQRKLARRVRFEVPERMETVAGLDISVRGEQGRAAAVVWHVDRQQVLEHVAVEGTVSFPYVPGLLSFREVPLLLQALAQLRTTPDVLMVDGQGLAHPRRCGLATHLGVLLDHPAVGVAKSRLFGRHAEPGPEKGSWTPLYDDGEVIGAVVRTRTGVRPVYVSVGHRITLEAAVALTLRCTTRYRLPEPTRLADQLSRA
>NC_015966.1|WP_155815845.1|702719_703316_+|hypothetical-protein
MLYANGNYRADRYGGRAWGVGLEAVVRLSERTDLAINPGLGFRRKEVAWAQNVEDLEASGVITSVFGRRDVDRFNLRLRGSHTFTRDLTLQSYLQWFWARGHYRDFQKLGDDGRLAPLAVPYDRERYGNPDFQQGTLNINLILRYEYRPGSTLYVVWTWGQQDWSAQGTMDVREAAQRLLERSPTSVLLVKWTYTWGA
>NC_015966.1|WP_029933155.1|700827_702804_+|carbohydrate-binding-family-9-domain-containing-protein
MKSCRMLVLGLCLGLVGMLQAQPRQAPTLRAVRLTGSLELDGHVEEAVWQQAPAATEFWQREPHDGQPATERTEVRVLYDDAALYVAFVCYDREPDRILRRLARRDRVVPADWVGVLIDSYRDRKTAFAFLVNAAGTKADFLILNDGNDEDFNWDALWEARVAMRPDGWSAEFRIPFTALRFSQADTLRWGINFGRIIGRKNEQVFWAYVPRASGGFVSRFGTLEGLEGIRPPRALLLTPYVVAGGTHWSRDLTPRYLDPISPTFRLGGDVQYNLTNNTILNLTVNPDFGQVELDEVVLNLTAFETFYPEKRPFFLEGTSIFQTVGTGDDGDLRTFLFYSRRIGRQPQGYYSLPDTGDAEDWRVVENPAAVPLLGAVKLTGKTANGWAFGLLDALTQRTYATFAHVNGGRQRMRTEPLTNYTVARMQRELPAPGSYVGLIGTTTWREAGAVRQAYTGGLDWRWNPGDYGLVTEGLFSFSRRQRPDAPPREGYQGQARIGSLRHPYVVGVVGANFATRDYDPNDAGFHTMTNVAITYIWTQLRYLRPWGPLLQVRLNQNYWWVYRLDPWLHLSRGISPNLHLQWRNFWWTRLGMNLESEGWDLYESRGAGLFRRPLSWNLWMGGRRTNADRWCCTRTVTTAPIGMAGGPGVSDWKPSCD
>NC_015966.1|WP_043760328.1|698680_700669_-|threonine--tRNA-ligase
MAGNGQQREVIRITFPDGSERTFPKGITGRELAEQISPRLAREALAIKVNGEVWDLTRPIEEDARVRILTWEDPEGKAVYWHSTAHLMAEALEALYPGVKFGIGPPIEQGFYYDVDLGGRKLSAEDLARIEEKMRELARRDVPYERIPVSKQEALEYFKKKGDPYKVELIEELEDGTITFYRQGNFTDLCRGPHVPSTGYIKHVKLLNVAGAYWRGDERRPQLTRIYGISFPKKKELDEYLHRLEEARKRDHRRLGRELELFTFSQKVGPGLPLWLPRGATLRETLINFLREEQIRRGYQPVVTPHIARLELYKTSGHYPYYKDSQFPPMIENPETGEGYLLKPMNCPHHIMIYADRPRSYRELPIRLAEFGQVYRYEQTGELSGLTRVRGFTIDDAHIFCRPDQVKDEFKNVIDLTLYVFRSLGFDEFEAQISLRDPNNREKYVGDDELWEQAEQAIREAAAEMGLQATEELGEAAFYGPKLDFMVRDALGRRWQLGTVQLDYILPERFDLYYIGADNQKHRPVMIHRAPFGSLERFIGVLIEHCAGNFPLWLAPVQVAVLPLSDELNDYAEAVGRRLLEAGFRVEVDTRTETIGYKIRQAEVQKIPYMLIVGRREREAGTVAVRKHGEGDQGPATLDEFIERLRTEIEAATRRATVSENA
>NC_015966.1|WP_014066289.1|698066_698609_-|translation-initiation-factor-IF-3
MNQTRVRAIAKADKFRVNEEIRAPRVRVVDPEGNHGIYDLKKALEMARQRGLDLVEIAPNANPPVCKIIDYGKFRYEQQKKEKEARRKQLAQQIKEIRFRPHTDTHDFEFKTRHARQFLEDGHKVKAWVQFRGRDIIYQDAGLDLLRRFIEALQDIAKIDQPPKMEGRRMTVILSPTKKK
>NC_015966.1|WP_012843133.1|697730_697937_-|50S-ribosomal-protein-L35
MPKVKTNSGAKKRFKVTATGKIKRRRAFHSHLLTKKSKKRKRHLRQPALVDATDVRRVRRLLHIGLKG
>NC_015966.1|WP_012843132.1|697362_697710_-|50S-ribosomal-protein-L20
MPRATNKVAARRRRKKILNMAKGYWGRRSKIYTIAKHAVEKALQYAYRDRRQRKRQFRRLWIIRINAAARQNGTTYSRFMGAVRQEDIQLNRKVLADLAVNDPNTFSQIVRAVSA
>NC_015966.1|WP_014066295.1|708186_709050_+|VWA-domain-containing-protein
MAYSAEISRTSPTAILFLLDQSASMQEPFGGAEQRGDAAPSKARVLADVVNRLLQNLILRCAKEDGVRDYFYVGVIGYGERVQPLIRPAEEYRVAGDLVPISHLAERPLRLEERLKKVPDGKGGFVEQRVKFPVWFDPHAKNGTPMCQALDLAASMVRTWIDLHPHSFPPIVINITDGEATDGDPLRYAQQLRSFATDDGETLLFNVHLSSSEEPAVELPASVDELPRDEYAVLLFQMSSLLPFTMRAAAEQEGYRVTMDTRGFVFNADPVALVRFLEIGTRPSTLR
>NC_015966.1|WP_014066296.1|709057_709747_+|hypothetical-protein
MQAPLVRTFWLPRDGSAPTACEDAFAVRPGWPFAAAVADGATESAFSGAWARHLVRCFCRELPATPEALQHRLAHWRATWQPDVPATLPWYVAAKLEEGAHAALLGLVVQPDGTWQAVAVGDAVLLHLRGNRLLAAWPIDDPGQFHHRPTLIGSREDSTPPVEGTGGRWTPGDAFVLATDALGAWLLGDDPTLPLRLTTGELARHVTAARRRHALRNDDVAAVVVHCPR
>NC_015966.1|WP_014066297.1|709755_711042_-|isocitrate-lyase
MRQPIAAVKAARLEAEWRSNPRWAGIRRPYAAEEVLRLRGSVEIAYTLADRGARRLWELLHTEPYVAALGALTGNQAMQQVKAGLKAIYVSGWQVAADANLAGQMYPDQSLYPSNSVPALVRRINNTLLRADQIHHAEGDDSIDWLVPIVADAEAGFGGPLHAFELTKALIEAGAAGVHFEDQLASEKKCGHLGGKVLVPTGQFIQTLVAARLAADVMGVPTIIIARTDANAATLLTSDIDERDRPFLTGERTPEGFFRVRAGLDQAIARALAYAPYADMIWCETSTPDLEEARCFAEAIHREYPGKLLAYNCSPSFNWKKHLDEATIARFQRELAAMGYKFQFITLAGFHTLNYAMFELAYDYAHEGMPAYVRLQQKEFAAMEKGFTAVRHQREVGTGYFDAVRTVITGEQASTVALAGSTETQQFH
>NC_015966.1|WP_014066298.1|711210_712728_+|helix-turn-helix-domain-containing-protein
MELNADLVRFALGLKLKALRQQRGLTLQDVASRAGLSVSYLSEIEKGKKFPKPDKLIDLASVFSVSYEELISPRLDERLDPLAAVFSSAFVQEFPFELFGLTPEDLFQLFTDQPTKAGALVRTFLEIGKMYDVQVEHFLFAALRSYQQLHNNYFPELEEAARAFRARYDLPAGEPIPPERLRRILEADYGYRIDTETLPRHPVLQGFRSVFAEGPQPVLFVNGRLLPAQQAFILARELGYRFLDLKERAITSSWLRVESFDQVLNNFRASYFAGALLLDETTLCADLRTFLSYPHWDGAVLRAFLKRYGATPEMLCYRLTELLPQHFGLRELFFLRLFHRPGTDRFQLTKVFNLSRVPVPHGIGLGEHYCRRWVAIQLLRRLAAQTPPPDPGDDPLVAAARMHFMNEDATFFTIALARPLVLTPEQNACVAIGFLLDAHCREQVHFAQDPALPDLEVNLTCERCPLADCAERAAEPEVYRAQQAQREREAALEALLEAMRRGQLP
>NC_015966.1|WP_014066299.1|712732_714559_+|hypothetical-protein
MPAFPTPGQYREAVQFPETAFVDPELQQATPEVDVLGLPWAISGAFATVFVLQGRARRWAVRCFHAPVPDLAERYRVLARHLERHPSLPFVDFAFQEDGIRVDDRTWPLLKMDWAEGVPLNRFVAEHLDEPEVLACLIEAWVALLKRLEGAGMAHGDLQHGNVLVAQESDRLKLTLVDYDAVYVPALRGRKSPELGHRNYQHPDRSEADFGPWIDRFPALVIYTALQALRHRPELGRRYPLDEALLFRAGDFYAPDRSPLFQELVGLEPIRPLVTLLRQACHLEPEQVPSLAEVHEGAVKAEPVQTRRRRPRRQPEATRGRFERAWLPGVLGTGALGAGLTLAVGLTAGVAVWGLGGLAMLGAALAHYRRLPIVRRRRRLRRELAFFDRLLERLHRQLDRIDVERRTFLAQQQTLRARRLEELREEALYDRLKYHFIDEAAQFEGLSHKVVIRLKAAGIRNAYQATPERVARARQLSDETRARVNLWRAGLVARYRDELPDRLSPAEELRLERYVHQRLARFEEERQRLFERMQVQQTERAQVAQRLATLPPLTFAHYLAYLLRWRPLPSPESAPAPPVPPPPSVVHTAPPAVSVALDEDRPWWEQAG
>NC_015966.1|WP_012844735.1|714643_715063_-|co-chaperone-GroES
MHRFRGELIIVGDRVLIEPDEGERQTQTGLYLPATVVERERVGTGRVVKVGPGYLMPNPEYSESEPWASHKEAVRYLPLQAQPGDYAFFLKKDAIELTYENRNYVIVPHSAILALVRPHTEDILENMDDLEDLDDLLNA
>NC_015966.1|WP_014066300.1|715106_716936_-|Na+:solute-symporter
MHLTWLDGVLIAAYFVFSLGIALYYYRRAGKDTSEFFLSGRSMPWWLAGTSMVATTFAADTPLAVSELVAYNGIAGNWLWWNFALGGVLTVFFFARLWRRSGVLTDVEFVELRYSGPAAAWLRGIKAVYFGLLMNVIIIGWVSLAMETVIDVLFPGRTLFGRTSFTLLGIEMSASLVLVGLLVLLVGVYSLISGLWGVAVTDLFQFVLAMVGTTLLAVFALDLPEVGGLAGLKARLPETTFRMLPTIGEAVQGAGVLALSAAAFAAYVGVQWWASWYPGAEPGGGGYIAQRMLGAKDERHAVFSVLWFNIAHYCLRPWPWILTALVALVLFPDEPPRAAYVLVMRDTLPPGLLGLLFAAFLAAFMSTVSTQLNWGVSYLVNDGWRRFVRPDADEKHYVRVGRVLTFLLAVVSVLVTTQLESISGAWSLILTASGGLGLVLILRWYWWRVNAWSELTATLVPLCLAGLALLGVPVPGLLDPFPTNLFAVVAYTTLAWVTVTLFTPPTDMATLDAFYRRVRPAGPGWRPIAARHPDIHPDTSLRTLAIDWLAGVVLVYSTLFGIGQLLVGSAGLGLLLLAVAVGAGAFLWRHLRHQLPHTTPAARNVPPTD
>NC_015966.1|WP_012844733.1|717029_717485_-|response-regulator
MKLLLIEPSQLRCRISNLLRLGGIEDVTEATSSTEALRLLQKQVVDLLLIGPTVTDPSGLELLRRVRQMEGHEDTAALIFLDMPTDELVLEAAELDVQGIIVVPFEDDYLLYRVRETLRKLRQRRQQAEKPAYRKRLHLVITSTPGQSSTS
>NC_015966.1|WP_014066301.1|717670_718837_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MQTLTVKCKLVLSKEHRDALDATMRAFAAACNDAIAVGRRLNTASNIRIHRVCYSDLRARHGLTANLAVRAIARAAGILKVKKRQCSTVRPTSIDYDARIFSFREADWTVSLSTVQGRIRVPIAVGAYQKRLLSSRKPTSAVVWKTRQGDYYIGIHINVETPPPEDEHGWIGVDLGIASIATLSDGTVFSGDQIERVRARYERTRRSLQRKGTRGAKRVLKRLSGRERRFQQSINHTISRRIVDRAIAEGKGVRLEDLSSIRKRVRARNKSQRRRIHRWAFYDLRTKIAYKCALAGVPFELIDPRYTSQRCPVCGHVEKANRKSQSEFVCRLCGLEANADVVGAINIALGGVVNRPEVALASVLTVLHGQNRNGSKSSYKPMTSVVGS
>NC_015966.1|WP_012844731.1|718819_719773_-|HDOD-domain-containing-protein
MHAARPTLSRLELRCPPLPQTLVEAMKLLNRPDQLEVKPITRLVERDPVVVARLLQIVNSAYYGLRRTVSSVERAVVLLGPVSVAGIIVGMHMLQLRTTLPGSAMACFNRLAQHCQATAFLARHLLETVLPRLSGQTSVGFTAGLLHDFGKIMLIYNFPQEAVGFYEQQRLQNEVQARDERHLEQLLFGCDHTEAGEYVARKLNFPDVLVDVIRYHHVPHQTPATSEAYMITPAVAVADLVARTMGYAFTHPLTPEQCLEHPAWRLLQQRYNLSDWTPRSLLTHLQEQQEFLDQHVQHLSLPNPPQRNRRVLSTTHD

Crispr_ID: NC_015966_4

• CRISPR_ID: NC_015966_4
• CRISPR_location: 1339694-1343322
• CRISPR_type: TypeIII
• Repeat_type: I-A,II-B,III-A
• Spacer_info: 54 spacers
• Cas_protein_info: cas2,cas1,csx1,csm3gr7,csx19,cas10,csm2gr11,csm4gr5,csm5gr7

Consensus repeat of NC_015966_4

Consensus_repeat	Method
GTTTTAATCGCACCTTTTTGGTATTGAAAT	PILER-CR
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CRISPRCasFinder
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CRT

spacers of NC_015966_4

>4.1|1339724|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TGAAGCACGCAAAACTCCTTCTGTTGCTGGCCGCC
>4.2|1339789|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TTGACAATGCCGATGTGGGCGCGCTGGCCTACATCAG
>4.3|1339856|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCAGGAACACCATGCTGCGGAGTGAGCGGATATTGG
>4.4|1339922|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ACAGGAAGGCAAGCTGACTGTCGCGATCCTGCAGGCCT
>4.5|1339990|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GGAGCACAGTTTTGTGCAAGCACCCGGCATATACTTC
>4.6|1340057|39|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GGCGTACCGCTGTCGCCGATCCTGTTGCGTGAGCGCATC
>4.7|1340126|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TGTACGACAAACGGAACTTGGCCCTCACGGCGAGCG
>4.8|1340192|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GACGGCGGCAAAGAAAGAATGACATTGCCGCCCTCAT
>4.9|1340259|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GGGTAGAGGCGCTCGTCCTCGTCCAGGACATAGACG
>4.10|1340325|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GTACAGATATTTCAGAGTCCACGATCCACAGATAAT
>4.11|1340391|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ATTGAAGAGCATCGGCGAGATGCCGTACGTGTCGGC
>4.12|1340457|43|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCACGTAAGAGGCATGAGAAAAGGAAGTATAACCTTCAGGCCA
>4.13|1340530|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CGTGTATGCCTACGAGGAGCTGAACTCGTACTGGCAG
>4.14|1340597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CTCCGAAAGAAGTTACTTCCTCAGTACAAAGAGCA
>4.15|1340662|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CTGGCCCTCGATCTGTACGCTTGGCTTTCGTATCGGG
>4.16|1340729|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AATAGCTGGTACGGGGAACTGAACTTGGCGAGGATGC
>4.17|1340796|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TACAGCTCCGACTGCAGCACGGCCGACAACCGCGCCCG
>4.18|1340864|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CTTGGAAAAAGTCTCGGTGGGTGATCGGCGCGTAA
>4.19|1340929|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CCTGAAAGCGCAAGGCCAGCTTCGCTACTGGCGCAACA
>4.20|1340997|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TTGCATAACCTAAAAAATGAACGCTATCCTTTAGC
>4.21|1341062|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GGAAATACTGTTTGTTCAACTTTCTGGCAAATTGCTC
>4.22|1341129|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCGGTAATTACATCTGGATCGATAATGGCTTTTAC
>4.23|1341194|39|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TATATTTCAACAACCACCCCTCTTTCTGAAGGGAATCCA
>4.24|1341263|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GATAGGGTGGCAACACCTCGCGGTAATCCTGCGGG
>4.25|1341328|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GTTGCCCGAGCCGGGCTGTTTCTTTTCACTCGTTGTG
>4.26|1341395|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCGCGTAATGCCGGGCTGGGTGTACATGTCTCCCGA
>4.27|1341461|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TTCGCCTTCCGTATGCCGCACCAGACAACGGCTTGCG
>4.28|1341528|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TGCAGCGCCTCTACGGCTGGTCGTGGCGCAAAGCGCG
>4.29|1341595|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ACGTCGCCGCCATCCTGGCCGCCTACCGGACGATCAA
>4.30|1341662|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GGCGAAAACTATCGTCATCTGGGGTGGCGCTTCCCGC
>4.31|1341729|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TTACGTTCAACGTCACGCGAAAATCCACGGTCTTCCA
>4.32|1341796|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AATCATGGCGTTGGATTACGCGCAGCGCGTCGTCGC
>4.33|1341862|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CTGGACCGAGACGCCGACCGACCAGCGATTGAAGGCCG
>4.34|1341930|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GTGACGGGCGCCATCGAATGGCTTGCCCAGGATGGCGT
>4.35|1341998|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ACCGCCCGCGCGTGGCGATCAGGTGCTCGGCCTCC
>4.36|1342063|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CGAAAAATACGATAGCTTTCATGATGCCCTCCTTCGG
>4.37|1342130|34|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ATTGGATTTTGTCGGCCAGCGGTCCTTCGGTAGA
>4.38|1342194|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCCAAAGCCCAAGGTCGACTGTCTAAAATCGCAGAG
>4.39|1342260|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GGCAGAGACGATGAAAAAGGCCGTGGACTACGAGTTCA
>4.40|1342328|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GAAGTGACCGAGAGCCGGATCGTCACCACTCTCAA
>4.41|1342393|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ATCTTCGATCTTATCGACGAGACGGCGCCGGTGAACTG
>4.42|1342461|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CTCTGCGGCTGGTAGGGGACAGGCAGCGCCACACGCT
>4.43|1342528|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ATCTGAAAAGCACGGGCAATCTGCTGGTCGACGTA
>4.44|1342593|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TCGGAACGCGGGCGTAATCGACCACCTCAGCCCCGACC
>4.45|1342661|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CGAAGCGGTAGCCGCGCCCGCTGGCGATCACCTCGG
>4.46|1342727|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TATGTTGGCCTCCGACTGGCCCACGAGCGACCCTT
>4.47|1342792|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AGGTCGCGAACAAGCTCTTGCGCAATGATGGTCGC
>4.48|1342857|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AGCTGCTTTGCAGCAGCTAGGACGATGGACGACACAA
>4.49|1342924|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ATCAGGTGGAGGATTCGATCGAGGGGTGGTGCTCGG
>4.50|1342990|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TGATCGATGCGACGCGCAAGGGCCACCCGCTGCACA
>4.51|1343056|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCAGGGACGCGCGGCGCTCAAGTACCAGCGAAGGCCG
>4.52|1343123|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ACGACTTGGCACGCCTGCGGGGCGCCAGGCTGGTAACG
>4.53|1343191|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GGGGTTGATTATGATATTGAAAGAAATGACGATTCC
>4.54|1343257|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GATCCTGCAGGTGTCCAGCGTAGCAGGTTCCGTACT

CRISPR arrays and Neighbor proteins around NC_015966_4

CRISPR arrays

The CRISPR arrays of NC_015966_4

>merge|NC_015966|4|1339694-1343322|PILER-CR,CRISPRCasFinder,CRT
GTTTTAATCGCACCTTTTTGGTATTGAAATTGAAGCACGCAAAACTCCTTCTGTTGCTGGCCGCCGTTTTAATCGCACCTTTTTGGTATTGAAATTTGACAATGCCGATGTGGGCGCGCTGGCCTACATCAGGTTTTAATCGCACCTTTTTGGTATTGAAATGCAGGAACACCATGCTGCGGAGTGAGCGGATATTGGGTTTTAATCGCACCTTTTTGGTATTGAAATACAGGAAGGCAAGCTGACTGTCGCGATCCTGCAGGCCTGTTTTAATCGCACCTTTTTGGTATTGAAATGGAGCACAGTTTTGTGCAAGCACCCGGCATATACTTCGTTTTAATCGCACCTTTTTGGTATTGAAATGGCGTACCGCTGTCGCCGATCCTGTTGCGTGAGCGCATCGTTTTAATCGCACCTTTTTGGTATTGAAATTGTACGACAAACGGAACTTGGCCCTCACGGCGAGCGGTTTTAATCGCACCTTTTTGGTATTGAAATGACGGCGGCAAAGAAAGAATGACATTGCCGCCCTCATGTTTTAATCGCACCTTTTTGGTATTGAAATGGGTAGAGGCGCTCGTCCTCGTCCAGGACATAGACGGTTTTAATCGCACCTTTTTGGTATTGAAATGTACAGATATTTCAGAGTCCACGATCCACAGATAATGTTTTAATCGCACCTTTTTGGTATTGAAATATTGAAGAGCATCGGCGAGATGCCGTACGTGTCGGCGTTTTAATCGCACCTTTTTGGTATTGAAATGCACGTAAGAGGCATGAGAAAAGGAAGTATAACCTTCAGGCCAGTTTTAATCGCACCTTTTTGGTATTGAAATCGTGTATGCCTACGAGGAGCTGAACTCGTACTGGCAGGTTTTAATCGCACCTTTTTGGTATTGAAATCTCCGAAAGAAGTTACTTCCTCAGTACAAAGAGCAGTTTTAATCGCACCTTTTTGGTATTGAAATCTGGCCCTCGATCTGTACGCTTGGCTTTCGTATCGGGGTTTTAATCGCACCTTTTTGGTATTGAAATAATAGCTGGTACGGGGAACTGAACTTGGCGAGGATGCGTTTTAATCGCACCTTTTTGGTATTGAAATTACAGCTCCGACTGCAGCACGGCCGACAACCGCGCCCGGTTTTAATCGCACCTTTTTGGTATTGAAATCTTGGAAAAAGTCTCGGTGGGTGATCGGCGCGTAAGTTTTAATCGCACCTTTTTGGTATTGAAATCCTGAAAGCGCAAGGCCAGCTTCGCTACTGGCGCAACAGTTTTAATCGCACCTTTTTGGTATTGAAATTTGCATAACCTAAAAAATGAACGCTATCCTTTAGCGTTTTAATCGCACCTTTTTGGTATTGAAATGGAAATACTGTTTGTTCAACTTTCTGGCAAATTGCTCGTTTTAATCGCACCTTTTTGGTATTGAAATGCGGTAATTACATCTGGATCGATAATGGCTTTTACGTTTTAATCGCACCTTTTTGGTATTGAAATTATATTTCAACAACCACCCCTCTTTCTGAAGGGAATCCAGTTTTAATCGCACCTTTTTGGTATTGAAATGATAGGGTGGCAACACCTCGCGGTAATCCTGCGGGGTTTTAATCGCACCTTTTTGGTATTGAAATGTTGCCCGAGCCGGGCTGTTTCTTTTCACTCGTTGTGGTTTTAATCGCACCTTTTTGGTATTGAAATGCGCGTAATGCCGGGCTGGGTGTACATGTCTCCCGAGTTTTAATCGCACCTTTTTGGTATTGAAATTTCGCCTTCCGTATGCCGCACCAGACAACGGCTTGCGGTTTTAATCGCACCTTTTTGGTATTGAAATTGCAGCGCCTCTACGGCTGGTCGTGGCGCAAAGCGCGGTTTTAATCGCACCTTTTTGGTATTGAAATACGTCGCCGCCATCCTGGCCGCCTACCGGACGATCAAGTTTTAATCGCACCTTTTTGGTATTGAAATGGCGAAAACTATCGTCATCTGGGGTGGCGCTTCCCGCGTTTTAATCGCACCTTTTTGGTATTGAAATTTACGTTCAACGTCACGCGAAAATCCACGGTCTTCCAGTTTTAATCGCACCTTTTTGGTATTGAAATAATCATGGCGTTGGATTACGCGCAGCGCGTCGTCGCGTTTTAATCGCACCTTTTTGGTATTGAAATCTGGACCGAGACGCCGACCGACCAGCGATTGAAGGCCGGTTTTAATCGCACCTTTTTGGTATTGAAATGTGACGGGCGCCATCGAATGGCTTGCCCAGGATGGCGTGTTTTAATCGCACCTTTTTGGTATTGAAATACCGCCCGCGCGTGGCGATCAGGTGCTCGGCCTCCGTTTTAATCGCACCTTTTTGGTATTGAAATCGAAAAATACGATAGCTTTCATGATGCCCTCCTTCGGGTTTTAATCGCACCTTTTTGGTATTGAAATATTGGATTTTGTCGGCCAGCGGTCCTTCGGTAGAGTTTTAATCGCACCTTTTTGGTATTGAAATGCCAAAGCCCAAGGTCGACTGTCTAAAATCGCAGAGGTTTTAATCGCACCTTTTTGGTATTGAAATGGCAGAGACGATGAAAAAGGCCGTGGACTACGAGTTCAGTTTTAATCGCACCTTTTTGGTATTGAAATGAAGTGACCGAGAGCCGGATCGTCACCACTCTCAAGTTTTAATCGCACCTTTTTGGTATTGAAATATCTTCGATCTTATCGACGAGACGGCGCCGGTGAACTGGTTTTAATCGCACCTTTTTGGTATTGAAATCTCTGCGGCTGGTAGGGGACAGGCAGCGCCACACGCTGTTTTAATCGCACCTTTTTGGTATTGAAATATCTGAAAAGCACGGGCAATCTGCTGGTCGACGTAGTTTTAATCGCACCTTTTTGGTATTGAAATTCGGAACGCGGGCGTAATCGACCACCTCAGCCCCGACCGTTTTAATCGCACCTTTTTGGTATTGAAATCGAAGCGGTAGCCGCGCCCGCTGGCGATCACCTCGGGTTTTAATCGCACCTTTTTGGTATTGAAATTATGTTGGCCTCCGACTGGCCCACGAGCGACCCTTGTTTTAATCGCACCTTTTTGGTATTGAAATAGGTCGCGAACAAGCTCTTGCGCAATGATGGTCGCGTTTTAATCGCACCTTTTTGGTATTGAAATAGCTGCTTTGCAGCAGCTAGGACGATGGACGACACAAGTTTTAATCGCACCTTTTTGGTATTGAAATATCAGGTGGAGGATTCGATCGAGGGGTGGTGCTCGGGTTTTAATCGCACCTTTTTGGTATTGAAATTGATCGATGCGACGCGCAAGGGCCACCCGCTGCACAGTTTTAATCGCACCTTTTAGGTATTGAAATGCAGGGACGCGCGGCGCTCAAGTACCAGCGAAGGCCGGTTTTAATCGCACCTTTTAGGTATTGAAATACGACTTGGCACGCCTGCGGGGCGCCAGGCTGGTAACGGTTTTAATCGCACCTTTTAGGTATTGAAATGGGGTTGATTATGATATTGAAAGAAATGACGATTCCGTTTTAATCGCACCTTTTAGGTATTGAAATGATCCTGCAGGTGTCCAGCGTAGCAGGTTCCGTACTGTTTTAATCGCACCTTTTAGGTATTGAAAT

>NC_015966|4|1|1339694-1343322|PILER-CR
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGAAGCACGCAAAACTCCTTCTGTTGCTGGCCGCC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTGACAATGCCGATGTGGGCGCGCTGGCCTACATCAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCAGGAACACCATGCTGCGGAGTGAGCGGATATTGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACAGGAAGGCAAGCTGACTGTCGCGATCCTGCAGGCCT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGAGCACAGTTTTGTGCAAGCACCCGGCATATACTTC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCGTACCGCTGTCGCCGATCCTGTTGCGTGAGCGCATC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGTACGACAAACGGAACTTGGCCCTCACGGCGAGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GACGGCGGCAAAGAAAGAATGACATTGCCGCCCTCAT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGGTAGAGGCGCTCGTCCTCGTCCAGGACATAGACG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTACAGATATTTCAGAGTCCACGATCCACAGATAAT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATTGAAGAGCATCGGCGAGATGCCGTACGTGTCGGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCACGTAAGAGGCATGAGAAAAGGAAGTATAACCTTCAGGCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGTGTATGCCTACGAGGAGCTGAACTCGTACTGGCAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTCCGAAAGAAGTTACTTCCTCAGTACAAAGAGCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTGGCCCTCGATCTGTACGCTTGGCTTTCGTATCGGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AATAGCTGGTACGGGGAACTGAACTTGGCGAGGATGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TACAGCTCCGACTGCAGCACGGCCGACAACCGCGCCCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTTGGAAAAAGTCTCGGTGGGTGATCGGCGCGTAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CCTGAAAGCGCAAGGCCAGCTTCGCTACTGGCGCAACA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTGCATAACCTAAAAAATGAACGCTATCCTTTAGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGAAATACTGTTTGTTCAACTTTCTGGCAAATTGCTC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCGGTAATTACATCTGGATCGATAATGGCTTTTAC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TATATTTCAACAACCACCCCTCTTTCTGAAGGGAATCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GATAGGGTGGCAACACCTCGCGGTAATCCTGCGGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTTGCCCGAGCCGGGCTGTTTCTTTTCACTCGTTGTG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCGCGTAATGCCGGGCTGGGTGTACATGTCTCCCGA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTCGCCTTCCGTATGCCGCACCAGACAACGGCTTGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGCAGCGCCTCTACGGCTGGTCGTGGCGCAAAGCGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACGTCGCCGCCATCCTGGCCGCCTACCGGACGATCAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCGAAAACTATCGTCATCTGGGGTGGCGCTTCCCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTACGTTCAACGTCACGCGAAAATCCACGGTCTTCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AATCATGGCGTTGGATTACGCGCAGCGCGTCGTCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTGGACCGAGACGCCGACCGACCAGCGATTGAAGGCCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTGACGGGCGCCATCGAATGGCTTGCCCAGGATGGCGT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACCGCCCGCGCGTGGCGATCAGGTGCTCGGCCTCC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGAAAAATACGATAGCTTTCATGATGCCCTCCTTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATTGGATTTTGTCGGCCAGCGGTCCTTCGGTAGA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCCAAAGCCCAAGGTCGACTGTCTAAAATCGCAGAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCAGAGACGATGAAAAAGGCCGTGGACTACGAGTTCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GAAGTGACCGAGAGCCGGATCGTCACCACTCTCAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCTTCGATCTTATCGACGAGACGGCGCCGGTGAACTG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTCTGCGGCTGGTAGGGGACAGGCAGCGCCACACGCT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCTGAAAAGCACGGGCAATCTGCTGGTCGACGTA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TCGGAACGCGGGCGTAATCGACCACCTCAGCCCCGACC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGAAGCGGTAGCCGCGCCCGCTGGCGATCACCTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TATGTTGGCCTCCGACTGGCCCACGAGCGACCCTT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AGGTCGCGAACAAGCTCTTGCGCAATGATGGTCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AGCTGCTTTGCAGCAGCTAGGACGATGGACGACACAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCAGGTGGAGGATTCGATCGAGGGGTGGTGCTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGATCGATGCGACGCGCAAGGGCCACCCGCTGCACA
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GCAGGGACGCGCGGCGCTCAAGTACCAGCGAAGGCCG
GTTTTAATCGCACCTTTTAGGTATTGAAAT	ACGACTTGGCACGCCTGCGGGGCGCCAGGCTGGTAACG
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GGGGTTGATTATGATATTGAAAGAAATGACGATTCC
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GATCCTGCAGGTGTCCAGCGTAGCAGGTTCCGTACT
GTTTTAATCGCACCTTTTAGGTATTGAAAT

>NC_015966|4|4|1339694-1343322|CRISPRCasFinder
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGAAGCACGCAAAACTCCTTCTGTTGCTGGCCGCC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTGACAATGCCGATGTGGGCGCGCTGGCCTACATCAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCAGGAACACCATGCTGCGGAGTGAGCGGATATTGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACAGGAAGGCAAGCTGACTGTCGCGATCCTGCAGGCCT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGAGCACAGTTTTGTGCAAGCACCCGGCATATACTTC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCGTACCGCTGTCGCCGATCCTGTTGCGTGAGCGCATC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGTACGACAAACGGAACTTGGCCCTCACGGCGAGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GACGGCGGCAAAGAAAGAATGACATTGCCGCCCTCAT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGGTAGAGGCGCTCGTCCTCGTCCAGGACATAGACG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTACAGATATTTCAGAGTCCACGATCCACAGATAAT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATTGAAGAGCATCGGCGAGATGCCGTACGTGTCGGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCACGTAAGAGGCATGAGAAAAGGAAGTATAACCTTCAGGCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGTGTATGCCTACGAGGAGCTGAACTCGTACTGGCAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTCCGAAAGAAGTTACTTCCTCAGTACAAAGAGCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTGGCCCTCGATCTGTACGCTTGGCTTTCGTATCGGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AATAGCTGGTACGGGGAACTGAACTTGGCGAGGATGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TACAGCTCCGACTGCAGCACGGCCGACAACCGCGCCCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTTGGAAAAAGTCTCGGTGGGTGATCGGCGCGTAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CCTGAAAGCGCAAGGCCAGCTTCGCTACTGGCGCAACA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTGCATAACCTAAAAAATGAACGCTATCCTTTAGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGAAATACTGTTTGTTCAACTTTCTGGCAAATTGCTC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCGGTAATTACATCTGGATCGATAATGGCTTTTAC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TATATTTCAACAACCACCCCTCTTTCTGAAGGGAATCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GATAGGGTGGCAACACCTCGCGGTAATCCTGCGGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTTGCCCGAGCCGGGCTGTTTCTTTTCACTCGTTGTG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCGCGTAATGCCGGGCTGGGTGTACATGTCTCCCGA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTCGCCTTCCGTATGCCGCACCAGACAACGGCTTGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGCAGCGCCTCTACGGCTGGTCGTGGCGCAAAGCGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACGTCGCCGCCATCCTGGCCGCCTACCGGACGATCAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCGAAAACTATCGTCATCTGGGGTGGCGCTTCCCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTACGTTCAACGTCACGCGAAAATCCACGGTCTTCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AATCATGGCGTTGGATTACGCGCAGCGCGTCGTCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTGGACCGAGACGCCGACCGACCAGCGATTGAAGGCCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTGACGGGCGCCATCGAATGGCTTGCCCAGGATGGCGT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACCGCCCGCGCGTGGCGATCAGGTGCTCGGCCTCC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGAAAAATACGATAGCTTTCATGATGCCCTCCTTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATTGGATTTTGTCGGCCAGCGGTCCTTCGGTAGA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCCAAAGCCCAAGGTCGACTGTCTAAAATCGCAGAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCAGAGACGATGAAAAAGGCCGTGGACTACGAGTTCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GAAGTGACCGAGAGCCGGATCGTCACCACTCTCAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCTTCGATCTTATCGACGAGACGGCGCCGGTGAACTG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTCTGCGGCTGGTAGGGGACAGGCAGCGCCACACGCT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCTGAAAAGCACGGGCAATCTGCTGGTCGACGTA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TCGGAACGCGGGCGTAATCGACCACCTCAGCCCCGACC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGAAGCGGTAGCCGCGCCCGCTGGCGATCACCTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TATGTTGGCCTCCGACTGGCCCACGAGCGACCCTT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AGGTCGCGAACAAGCTCTTGCGCAATGATGGTCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AGCTGCTTTGCAGCAGCTAGGACGATGGACGACACAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCAGGTGGAGGATTCGATCGAGGGGTGGTGCTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGATCGATGCGACGCGCAAGGGCCACCCGCTGCACA
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GCAGGGACGCGCGGCGCTCAAGTACCAGCGAAGGCCG
GTTTTAATCGCACCTTTTAGGTATTGAAAT	ACGACTTGGCACGCCTGCGGGGCGCCAGGCTGGTAACG
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GGGGTTGATTATGATATTGAAAGAAATGACGATTCC
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GATCCTGCAGGTGTCCAGCGTAGCAGGTTCCGTACT
GTTTTAATCGCACCTTTTAGGTATTGAAAT

>NC_015966|4|1|1339694-1343322|CRT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGAAGCACGCAAAACTCCTTCTGTTGCTGGCCGCC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTGACAATGCCGATGTGGGCGCGCTGGCCTACATCAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCAGGAACACCATGCTGCGGAGTGAGCGGATATTGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACAGGAAGGCAAGCTGACTGTCGCGATCCTGCAGGCCT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGAGCACAGTTTTGTGCAAGCACCCGGCATATACTTC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCGTACCGCTGTCGCCGATCCTGTTGCGTGAGCGCATC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGTACGACAAACGGAACTTGGCCCTCACGGCGAGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GACGGCGGCAAAGAAAGAATGACATTGCCGCCCTCAT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGGTAGAGGCGCTCGTCCTCGTCCAGGACATAGACG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTACAGATATTTCAGAGTCCACGATCCACAGATAAT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATTGAAGAGCATCGGCGAGATGCCGTACGTGTCGGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCACGTAAGAGGCATGAGAAAAGGAAGTATAACCTTCAGGCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGTGTATGCCTACGAGGAGCTGAACTCGTACTGGCAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTCCGAAAGAAGTTACTTCCTCAGTACAAAGAGCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTGGCCCTCGATCTGTACGCTTGGCTTTCGTATCGGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AATAGCTGGTACGGGGAACTGAACTTGGCGAGGATGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TACAGCTCCGACTGCAGCACGGCCGACAACCGCGCCCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTTGGAAAAAGTCTCGGTGGGTGATCGGCGCGTAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CCTGAAAGCGCAAGGCCAGCTTCGCTACTGGCGCAACA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTGCATAACCTAAAAAATGAACGCTATCCTTTAGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGAAATACTGTTTGTTCAACTTTCTGGCAAATTGCTC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCGGTAATTACATCTGGATCGATAATGGCTTTTAC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TATATTTCAACAACCACCCCTCTTTCTGAAGGGAATCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GATAGGGTGGCAACACCTCGCGGTAATCCTGCGGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTTGCCCGAGCCGGGCTGTTTCTTTTCACTCGTTGTG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCGCGTAATGCCGGGCTGGGTGTACATGTCTCCCGA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTCGCCTTCCGTATGCCGCACCAGACAACGGCTTGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGCAGCGCCTCTACGGCTGGTCGTGGCGCAAAGCGCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACGTCGCCGCCATCCTGGCCGCCTACCGGACGATCAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCGAAAACTATCGTCATCTGGGGTGGCGCTTCCCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TTACGTTCAACGTCACGCGAAAATCCACGGTCTTCCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AATCATGGCGTTGGATTACGCGCAGCGCGTCGTCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTGGACCGAGACGCCGACCGACCAGCGATTGAAGGCCG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GTGACGGGCGCCATCGAATGGCTTGCCCAGGATGGCGT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ACCGCCCGCGCGTGGCGATCAGGTGCTCGGCCTCC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGAAAAATACGATAGCTTTCATGATGCCCTCCTTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATTGGATTTTGTCGGCCAGCGGTCCTTCGGTAGA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GCCAAAGCCCAAGGTCGACTGTCTAAAATCGCAGAG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GGCAGAGACGATGAAAAAGGCCGTGGACTACGAGTTCA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	GAAGTGACCGAGAGCCGGATCGTCACCACTCTCAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCTTCGATCTTATCGACGAGACGGCGCCGGTGAACTG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CTCTGCGGCTGGTAGGGGACAGGCAGCGCCACACGCT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCTGAAAAGCACGGGCAATCTGCTGGTCGACGTA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TCGGAACGCGGGCGTAATCGACCACCTCAGCCCCGACC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	CGAAGCGGTAGCCGCGCCCGCTGGCGATCACCTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TATGTTGGCCTCCGACTGGCCCACGAGCGACCCTT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AGGTCGCGAACAAGCTCTTGCGCAATGATGGTCGC
GTTTTAATCGCACCTTTTTGGTATTGAAAT	AGCTGCTTTGCAGCAGCTAGGACGATGGACGACACAA
GTTTTAATCGCACCTTTTTGGTATTGAAAT	ATCAGGTGGAGGATTCGATCGAGGGGTGGTGCTCGG
GTTTTAATCGCACCTTTTTGGTATTGAAAT	TGATCGATGCGACGCGCAAGGGCCACCCGCTGCACA
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GCAGGGACGCGCGGCGCTCAAGTACCAGCGAAGGCCG
GTTTTAATCGCACCTTTTAGGTATTGAAAT	ACGACTTGGCACGCCTGCGGGGCGCCAGGCTGGTAACG
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GGGGTTGATTATGATATTGAAAGAAATGACGATTCC
GTTTTAATCGCACCTTTTAGGTATTGAAAT	GATCCTGCAGGTGTCCAGCGTAGCAGGTTCCGTACT
GTTTTAATCGCACCTTTTAGGTATTGAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_155815873.1|1355542_1355854_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_032833207.1|1345936_1346332_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl|CDD|367635
NC_015966.1|WP_014066772.1|1332494_1333367_+|CRISPR-associated-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	gnl|CDD|187814
NC_015966.1|WP_155815871.1|1354825_1355368_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014066777.1|1336066_1337317_+|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	gnl|CDD|378186
NC_015966.1|WP_014066776.1|1335071_1336070_+|CRISPR-associated-protein-Csx14	csx1	cd09741_csx1_CAS-III	gnl|CDD|187872
NC_015966.1|WP_014066784.1|1348125_1349568_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl|CDD|187793
NC_015966.1|WP_029933113.1|1353953_1354757_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014066770.1|1330740_1331577_+|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|376187
NC_015966.1|WP_081472067.1|1351183_1353982_-|hypothetical-protein	unknown	unknown	gnl|CDD|379311
NC_015966.1|WP_012844126.1|1339166_1339433_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|187856
NC_015966.1|WP_014066778.1|1337396_1338086_+|exonuclease	unknown	unknown	gnl|CDD|99825
NC_015966.1|WP_014066773.1|1333363_1333804_+|hypothetical-protein	csx19	mkCas0188_csx19_CAS-III-D	unknown
NC_015966.1|WP_014066780.1|1343445_1345902_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl|CDD|187811
NC_015966.1|WP_014066771.1|1331593_1332484_+|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187814
NC_015966.1|WP_014066779.1|1338082_1339165_+|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl|CDD|274695
NC_015966.1|WP_155815869.1|1347131_1348112_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl|CDD|224483
NC_015966.1|WP_014066774.1|1333790_1334774_+|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_015966.1|WP_014066785.1|1349584_1350931_+|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	gnl|CDD|274263
NC_015966.1|WP_029961412.1|1346334_1347138_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|187815

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015966.1|WP_014066772.1|1332494_1333367_+|CRISPR-associated-protein	csm3gr7	COG1337_csm3gr7_CAS-III-D	1.5e-31	104.4	0.0
NC_015966.1|WP_014066774.1|1333790_1334774_+|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	3.2e-35	116.9	0.1
NC_015966.1|WP_014066776.1|1335071_1336070_+|CRISPR-associated-protein-Csx14	csx1	cd09741_csx1_CAS-III	2.8e-40	132.9	0.0
NC_015966.1|WP_014066784.1|1348125_1349568_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	4.7e-22	73.4	0.0
NC_015966.1|WP_012844126.1|1339166_1339433_-|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	3.9e-27	89.0	0.4
NC_015966.1|WP_014066777.1|1336066_1337317_+|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	3.9e-72	238.2	0.0
NC_015966.1|WP_014066773.1|1333363_1333804_+|hypothetical-protein	csx19	mkCas0188_csx19_CAS-III-D	3.7e-68	222.5	0.0
NC_015966.1|WP_014066780.1|1343445_1345902_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	1.1e-138	458.3	0.0
NC_015966.1|WP_014066771.1|1331593_1332484_+|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	7.2e-64	209.9	0.0
NC_015966.1|WP_014066779.1|1338082_1339165_+|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	2.3e-121	399.6	0.0
NC_015966.1|WP_155815869.1|1347131_1348112_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	4.5e-52	171.9	0.0
NC_015966.1|WP_032833207.1|1345936_1346332_+|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	8.3e-23	75.8	1.7
NC_015966.1|WP_014066785.1|1349584_1350931_+|TIGR02710-family-CRISPR-associated-protein	csx1	cd09702_csx1_CAS-III	2.2e-83	274.8	5.1
NC_015966.1|WP_029961412.1|1346334_1347138_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	2e-68	225.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_014066772.1|1332494_1333367_+|CRISPR-associated-protein	gnl|CDD|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.28779e-26
NC_015966.1|WP_014066777.1|1336066_1337317_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	4.68532e-67
NC_015966.1|WP_014066776.1|1335071_1336070_+|CRISPR-associated-protein-Csx14	gnl|CDD|187872	cd09741, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	3.27122e-37
NC_015966.1|WP_014066785.1|1349584_1350931_+|TIGR02710-family-CRISPR-associated-protein	gnl|CDD|274263	TIGR02710, conserved_hypothetical_protein, CRISPR-associated protein, TIGR02710 family. Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Archaea), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	1.07495e-75
NC_015966.1|WP_014066770.1|1330740_1331577_+|nucleotidyltransferase-domain-containing-protein	gnl|CDD|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	2.30241e-17
NC_015966.1|WP_081472067.1|1351183_1353982_-|hypothetical-protein	gnl|CDD|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	2.18025e-05
NC_015966.1|WP_014066774.1|1333790_1334774_+|hypothetical-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.28046e-20
NC_015966.1|WP_014066778.1|1337396_1338086_+|exonuclease	gnl|CDD|99825	cd05782, DNA_polB_like1_exo, Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases. A subfamily of the 3'-5' exonuclease domain of family-B DNA polymerases. This subfamily is composed of uncharacterized bacterial family-B DNA polymerases. Family-B DNA polymerases contain an N-terminal DEDDy DnaQ-like exonuclease domain in the same polypeptide chain as the polymerase domain, similar to family-A DNA polymerases. This exonuclease domain contains three sequence motifs termed ExoI, ExoII and ExoIII, with a specific YX(3)D pattern at ExoIII. These motifs are involved in metal binding and catalysis. The exonuclease domain of family-B DNA polymerases has a fundamental role in proofreading activity. It contains a beta hairpin structure that plays an important role in active site switching in the event of a nucleotide misincorporation. Family-B DNA polymerases are predominantly involved in DNA replication and DNA repair.	1.22715e-23
NC_015966.1|WP_014066784.1|1348125_1349568_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl|CDD|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.9756e-21
NC_015966.1|WP_012844126.1|1339166_1339433_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.35167e-29
NC_015966.1|WP_014066771.1|1331593_1332484_+|CRISPR-associated-RAMP-protein	gnl|CDD|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.61611e-68
NC_015966.1|WP_014066779.1|1338082_1339165_+|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	6.68442e-157
NC_015966.1|WP_155815869.1|1347131_1348112_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl|CDD|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.47385e-45
NC_015966.1|WP_032833207.1|1345936_1346332_+|type-III-A-CRISPR-associated-protein-Csm2	gnl|CDD|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	3.25153e-24
NC_015966.1|WP_029961412.1|1346334_1347138_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl|CDD|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.24488e-78
NC_015966.1|WP_014066780.1|1343445_1345902_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl|CDD|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	2.22595e-134

Protein sequences

>NC_015966.1|WP_012844126.1|1339166_1339433_-|CRISPR-associated-endonuclease-Cas2
MPYYIAVYDVNVRRVAKMLKLFRRYLTWVQRSVFEGELTEAQFQRLQHEAGRLMNPDEDVVIFYELRDVRYSRRLVLGTEQGHRDRFL
>NC_015966.1|WP_014066779.1|1338082_1339165_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKRPYYIFSSGRLRRRQNTLFFEKAAGERIPDDQDETGVPSGTPTGESIPFPVEQVESLYFFGEVDLNSKLLTFLARHDIPAHFYDYYGNYTGTYIPRDYLHSGRLRIEQVLHYVRPKRRRYLARAIVEAATYNLLRVLRYYVNRLEGERREAVAEAITTIEQERTQLRSVEKIPELMGIEGRSREAYYSAWPSILADGPGEAFVFEKRERRPPSNEINALISFGNSLCYTTTIRQIHRTALDPTISYLHEPGARRFSLALDLSEIFKPILVDRAIFRLVKTGEITPRHFEERLGGVYLKEEGRRIFVRHWDERLRQTVYHRRLERHVSYERLIRLECYKLIRHLLDPKNEPYRGLHMWW
>NC_015966.1|WP_014066778.1|1337396_1338086_+|exonuclease
MHYLALDIETCPLPADGYSAQQQARLAREVHFLRQREPDAHEEALTQRAASLHPLLSWIVCISVQRAADDPFQPNPPYSYLAPTPDEEGAMLARFWRDVQQFVERGEKICWITFNGKRFDVPFLLARTLHHGLSPVACGLLDDYPYKQYPHCDLFNLFAGINLGLADLCALLHISSPKEHGDGSLVQHLLETEGIEGVRRYCEADVVATMACFARLLPLLPRDCQPPSS
>NC_015966.1|WP_014066777.1|1336066_1337317_+|TIGR02221-family-CRISPR-associated-protein
MSTLLTFLGTGEYESVTYVCQEPDGEQAYRTHLFPLAAYHIFHPERILLPATYEVREGKGKKHYETLQRELTKEGVSIEVLMIPDGKSEAELWEIFATLAEKVTNEEQLILDITHAFRTLPLLVFAIAVYLRSAKHVQIERILYGAYEAREGDRAPIFDMTPLLDLVDWMGGVEFFLRRSDAVLLGERLERVHRQAWQQRKNGELPRKLQTLGTGLKNFSEALHLARPLEVMEKAEGLLRRLDDVGSEVRSWAQPFGVVLERVRQEAEKFAYSEPYRLNAENLCRQLALIRHYVEKGLTMQAVTLAREWVVSWVILQRGEENWLDESHREQVEQALGAAAQRSQKKEAQVPEWFDQLPNSQRLGELWNRLGQLRNDVAHCGMRKDQSTVKRIRERLKKLCKCLSDLYCEQSSSIAT
>NC_015966.1|WP_014066776.1|1335071_1336070_+|CRISPR-associated-protein-Csx14
MRRVLLATLGETPAVITEAIDKLRSEGVHVDVVVLLTTKDAFAREALELLSRHVPSYYNGEIEFHGARILEAFYDVDSDTAALEFMHLACAALRDYRKMGWEVYASIAGGRKAMSALLTLAVQFYGAQRLFHVLVDDLELEEEGHIQKLKNKLPQEQNRVLHPPVEHIKLVNLPFIGLLPLLGDIVAGLKGSPMRSEVQALLEHNGLLAEGQPTSLGKMILQVLESIETLPEPRQGECEKNLARKEPKEAEQTRLWAERLERRFLFIERIEDIGWREGQPKVKAEAPNLLIVFLPGRRIPGIGFQLTTTAKTSGQLERARQEVERWLEREVR
>NC_015966.1|WP_014066774.1|1333790_1334774_+|hypothetical-protein
MRPRNPNAEPKPFVWIPIPRESPRRGQPTTHERFSGLTGKLELTFTVVSEYLFVGSGAYEFDPNHNNQRPDVWYTFYRRNGQICVPGTSIKGAIRAIVEAISNSCISQFRRSREKVDKDHEPCRDQNKLCPACRLFGMTGLRGRVHFSDAFPEGQVRPQIVKIGELWEPRNYSGRKFYEVKRVPQLTDKRPQRNFRFVEAMSEGTCFRATLHFENLSEAELGLMAYALGWKTEKGTFDHAFTPKLGGAKPRCFGAVKFDPARLTVWEVQKNGLLQLRMLEGDAVGAKLVRCMEAASRPETGLFHESSWRRLVEGYQEKTDTCPREMY
>NC_015966.1|WP_014066773.1|1333363_1333804_+|hypothetical-protein
MNGFVYEGELRAEELEDLRTRLGLSITLSWKLARLDFAAELREGGSAFGPACELRWTRLDGEQFRVLLLCDAPQSDISPLEAVPGTWTQTEEITQLVNLDAPQFAPQFQQYPVVHAPVARLRCRVFYRGGIAMFVSPREVMSDAST
>NC_015966.1|WP_014066772.1|1332494_1333367_+|CRISPR-associated-protein
MHRRLWNTFKLTFELEPRAPLLVKSGMLSPNPALPDMQFVRTQTPEGEKLFIPGSSLKGTFRSFTEKVLRTANGRWACDPFSDSACGRQLRSEEDTTAVYRRSCNACKIYGNTRLRGRLSFTDALPEGEVVTETRYGVAISRLTNAAVGPFDIEVLVQGRFAGALVLQNFEVWQLGLLTLTLQAINDGLVRIGFGKNRGFGEVRIRPTQIIVEQAKHAGLGAGDLWGVGAFVQEEERRAYGLRQDDRLTGLPSAEEQDLVLYVRRTYSTEQWDAIARKTIEGLSLLEESA
>NC_015966.1|WP_014066771.1|1331593_1332484_+|CRISPR-associated-RAMP-protein
MADFWRFENRTIIESMLVMRTALSVGSRASFLPAGTDLPVIKTPEGIPYIPGSSLKGVVRSYVERLLRTIDALGRKHQGQRLWACDPLNEQDRCVIATCGPSCEQCEDCRGNCCTNCSRCKRCITNRVTENGRISDQRLAHELWAQSCTVCRLFGSPWLASRVAFQDAHLVNAEAMLHLTEVRDGVGIDRDLGAAKTGIKYDFETVPAGARFGITIVVENAERWEIGLLLLALEAMDRAALPVGGKSTRGLGWGTLEDVRIKRIEAQHLLDWLAGTYTPAPLNAQELIAELTAVLQ
>NC_015966.1|WP_014066770.1|1330740_1331577_+|nucleotidyltransferase-domain-containing-protein
MSIIEKYRHLPTLPADLAERLEKVPALLERHPVRLAYLFGSVACASESCQDRDIAVLPDEGFSYTNLYADLSLALNTDRIDLVDLRLTPPYLVAEILLKGRCILAKSADERARFKSGKCSEWRGNRWRWVRNLEKEEATNHQPEFLGNAVSEPERIAQELEKYQHTTEEQLATNLSFRWTVEGGLFAGLTVIFQGADHILSRAFGRTPASYEELIAELRAVNIISEELYPSDAWLRRFPQRTGSRARVDRSEPGVRRSPAVFRRFRQEILQWLQHRPL
>NC_015966.1|WP_014066780.1|1343445_1345902_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MYHQERETLYLGALLHDLGKFRQRAHDERTKHALISVAIIDRLIGTRTDAEQIKTLVSYHHREDLSQSGLQGRLRKLAEIVCEADSLASGERNPDIEQAQRPLESIFSHVRLEQSAGASPQVAWQPISELSADAYRFPTFSIADLEADYRRHWDAFEKALGKIENLKALPHPSTLLALLKKYLWCIPSAAYKTRPDVSLYEHSRLTAALALCMYDYLTEKYGDLNRAPVERRDEVRYRLVCGDLTGIQRYIYNIAHKGALRALKGRSFYLQLLLQVAARDLLNRLHLPLACLLYASGGKFYILAPDTDAFNRELADFEQTLQTWLLQRYDGAIGLVMAHIPLCGNDFAGSDGAHPIASKWEEVTEQIEQKKRQPFAGAITAADFWEPQEPGGQVVVCHATGRYLCRSDEIAEKHRNREIFPAEEAENRFISAEQHEAQRLGRALREAQAIELIREADGQQGYALFNGWHFRVHTQTPSLENNTTASPGFFDLSRELIWFDPKQLREHTLPQSWHFYAGNWSFEGDFNEVAAKAQGSKLLGALRMDVDNLGRIFRDGLGKDATFSRVVQLSTMMDFFFSGYLNRLQQLRWQTEQGVVEAKGEGMQLSEGMQIVYAGGDDLFIVGVWNVLPDVARWIRQQFQAFTAKNPYLTLSGGIALFPPKLPLYHAAQEAGHAEEAAKHFQRRVGSNGTVVTKNALNFLGVSVSWNDLAFLREWTADLYQAIEAKQLSRGILRRLYLAHESYQRHGRNPWGPWRWRTCYYLARYQEQHKAVADKINQLAAELFCSTRTESDLISIIHLLARWTEMLTRKEEDYAHQI
>NC_015966.1|WP_032833207.1|1345936_1346332_+|type-III-A-CRISPR-associated-protein-Csm2
MFKWIQEGLDKEAISYAEAFGKCLAKDKKSKNKEERYSALTTSQIRNFYGEVVRMRMRGFDRNRFLLMKPRLVYATSRNETDGSRDFLAVFKQAIDAVLEADNEEKAKEYFQRFADFFEAVLAYHRAYGGK
>NC_015966.1|WP_029961412.1|1346334_1347138_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MERQMITGKLVKKIRVRGFIKALTGLHIGGSNLEMGIGGADATVIRNPITNEPYIPGSSLKGKMRALLERLHVGEEYARSFGEGFGANSNVQQFVFKDIRHPIVQLFGTTPEEVRKQNLPEQPVARLIVRDCLLTRKWAQKLRDSEHTDMPFTEVKTEVAIDRVTSAAVPRQLERVPAGAVFRMEQVINVYEGDDEQKLLNLLFEGLMLVQHDYLGGKGSRGSGQVRIVVRQVAYRDRTSYAESKDWELYNQVAIPQELQVSSRAAS
>NC_015966.1|WP_155815869.1|1347131_1348112_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MMNLLGYRLQFPNGLHVAAEGFGEESVSPTVPSDTLFSAVCVSAFWLYGAEGVERLLKPGAVRLSSTFPFVGTEYFFPRPLSFFPKIPNEQYELLKRIKKVRYLSRTLFEQVLEGTQPEIRSDQIRGLFWFAGPPPDEPVMQTEVRPRVALDRVTQASEIYHFAEVHFNPRLDAGLFFLAQFEDPKVQQLFESALALLADEGIGADRTMGKGWFRWEREELTIRVPEATDRAVLLSLYNPTPEEAVAIAPYDSCYALVTRRGWVTVPGAMTLRRRPVRFFAEGSVLRFISQHMPQGRLVVVLSEKDAPELTHPVYRNGQALALPIR
>NC_015966.1|WP_014066784.1|1348125_1349568_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MERQRQAIRSIVEEVQGYLEVLTPVHIGSGIKWQRNLDFVVDAEGTYIVPESALIRYLQAHPEAIDRLEDEREREDLLWEVEDGIEYILPCESREILVFIRDGNGYPFVPGASLKGAIRTMLFRYFWDQLSPQKQADLLRNTQPRREWAAQPLLKEVFGKDPNHDLMRVLAVRDVQVRQQDLDLYRVFVLRLTDPEGKHYDWRGMRRRRTFSVIYAEMLRPGTTASFSMRLDRFLLEDERARSELHFDRKAFDFAKLARWANAYARKRLQRELAFLEKCNDGALNGLLNSLDALLQRIPDESDPEAGQRFLLRLGWGSGWQSMTGDYLEGEWLEKIRKRYRLNYDDRQRGRAHFPIFPKTRKIVFDGDRPAYLSGWVQIWLGKRPPADTRVTETQQVPAVEATPTVSTAPSLPKGLETGTIHSLNLKKMYGKVQPDKGGEPIRFDFQDAVMAGLEKGVRVSYRTVERGGELRAVEVKRYG
>NC_015966.1|WP_014066785.1|1349584_1350931_+|TIGR02710-family-CRISPR-associated-protein
MTHEMRRILVLNVGRPQDGNVETRPEAYALQETEPNYVVFICSEKGLDHAGTQEFVRQYANLVNLSADCYEELLLEDPDDLAQIYEQVAQKLAELRQRWPLARIFVDYTAGTKSMSAGLAMAAIDQEDETIEGQQIELRLVKGSRGKFSTVVPGTEAFRPVEGIHDLRARRRLKMVRAVLGQFDYAAATKWLHEMIRTGISERLANKLRHAYHLYHAFDAWDRWDLEEAGRILELDVYRRFPSGEQHVYERLKVLRALKSVRAAFEGKGRLDETGDPYVAVEDLLFNAERRVAQGRYDDAIARVYRAFELLAQIRLRAQYGVDTSRVDPKKVPEAVRSDLQPGRSDEIKVGLMQAWRILKAYPDEPLGQWFSIHQERLLKWLEQRNQSILAHGLYALGERDWRDRGAEGVDLCRDALRALEAFRKPRIAHVQLPRDELLEVFMSAEAS
>NC_015966.1|WP_081472067.1|1351183_1353982_-|hypothetical-protein
MRLKLSGRSSMHRPWIFFALILVLAACFPHALLSQVGDPLGSVPSCEDDPIADLQAAVDTPDRLPAMARKLGKALDSGCYFGQEAEIARIVAPIWQACPQDPETIHALWSLFSPISLAINIEDSSLARRLFIEVPLTCLEKQPASWENWFPILQSYLPTPAFADAGPQALSRLMELAGNNPNRWDQIVHLFGEMYFSEFPALTAAQVDRLIDHAGNAIWELPEIFARFPGRSGTEALLRFAEREHFAIPPEVAPYAEASKLRRDAIWRLEDRELTPEDLRRVAALAASEDELVAGSAIGVLLKHKEVLHSVPLSEGILDRLAYRMRVDKGGCQIAGIFATQGRAGAEQLYAYWLKVQEGRARDCGWDLEEALRRAAPHLRAELMQRYHATKDARLIPYLVAAGETGLVAEIARSASDAKVRGEAVRQLAAYLPDHPEDAQAREVLRRAALEELNPDAWHALLKVEDPEADWDRLAAMLERETPDRERLLRMFPAPAPQSVLEALLDLAAGATNRLHRILAIQAALRTPKWALSELSASYTPAEKAKEKEIKDKARAVLQHVYALEPKVRALLNDPDEEVRRAAIDWLAVVPAQEVATTEALLALLKDADDYVRNRAADALARAEVTPPGLLAHLEGRIAMDSPVYIQLLRKDPEAVDQLVAIVLHRKGNARTRQLLAKAEALPPSIARAFLARLDAEPMRSWLPQEGFSLLDILRAAEDPPAWDLISNLVPDTLRNAWLVEKAEQPNLTWKQRLRLLQMVSGETPASVRDRMLNLWIEAVRADAVSASLFLDGFLRHFGYKGIQALVDEFWNEVELLERVEGLWIKANNVGGLRAATGSAGGGVPGPGEEHLPWITEHVNELAETRDVRRLRAFLTVANVYTLGSDGTLQLQRAAFKAGITPALLRHIDDPEWCRAAQPLNALLDRMLPPRC
>NC_015966.1|WP_029933113.1|1353953_1354757_-|hypothetical-protein
MSADLSNEKKLGVYFLDTTGKTEVLKIGYDEILNRLFAEGMVPPSWAKQEKPLKAWRSLSVIPLPRAGWASEMGRPVLCSDEVVIVPLWVNCIQIDCDPNNLPVYLILRRAGKQYALYRPEKARYDEEYGWMSPDLVVPLGDKVISIDLEEGSYKILGEAKTYPLPLLSSLREGQSARFGGYVMEIREGAVVIHLRYLNPNKPYDPKTRSALDTRLAGVISAVLFPDRLLLKQTLLWPSETAPILPGWPREYDSRAVYYEIETIGKE
>NC_015966.1|WP_155815871.1|1354825_1355368_-|hypothetical-protein
MSTPAARPTGSSDPIRIIYPTNGSVIANDWATLLVEVNLPCALFDLEVLKDGKVEVARTYNTAVGRVEPHFYFLPLSPGKHTIAVRATGEAIPQCQGIREYRKTIDLVAHPGPLRFKPLDEDTYRELRWRFDRTIAGFSPVAWTAHTALIRTRSDSLERVWVVPREDEEKALQIIDGPLI
>NC_015966.1|WP_155815873.1|1355542_1355854_-|hypothetical-protein
MRMGQAGEAFIQSLKEALEMVRQETPEAGPLIVGQVLENEGSTERERDLLRKLRTLAFASWLATHGLGDAASLAYSIGTGVGGYEGIFSRLDDGRYEVVPSIQ

Crispr_ID: NC_015966_5

• CRISPR_ID: NC_015966_5
• CRISPR_location: 1442301-1444253
• CRISPR_type: Unclear
• Repeat_type: I-A,II-B,III-A
• Spacer_info: 29 spacers

Consensus repeat of NC_015966_5

Consensus_repeat	Method
GTTTTAATCGCACCTTTTTGGTATTGAAAT	PILER-CR
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CRISPRCasFinder
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CRT

spacers of NC_015966_5

>5.1|1442331|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CATGAGCGAGCCATTCCCATTCGTCACCGAGATCTGA
>5.2|1442398|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AGCGCCCGCATCCGGTTGCGTACAGCCACACTCGTTT
>5.3|1442465|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CCTGGAAGTTCATCCATCACATGGTCAGCGAAGAT
>5.4|1442530|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TTGGTCGTAATGCTCCAACCGCCAATCGTGCCTGATG
>5.5|1442597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AGTTAGAAAAGGTAGCCCAGGAAAGGGGCTTTAGG
>5.6|1442662|39|NC_015966|PILER-CR,CRISPRCasFinder,CRT
ATGCTGCCTTTGACTGTGATCTGCACGGTGCATATAGAC
>5.7|1442731|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GTCCTTCGGTAGAGCGTTTGGTGCCGGTAGAACGTC
>5.8|1442797|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TCGGACCAGACGGCGCCCCAGTCCTCGTATACAAGGA
>5.9|1442864|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TTGCTATATATCATATTTCACGCGTTCGCTTTCGAAGT
>5.10|1442932|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AAGGACGCAGTACTTCGATAGGCCTTCGTCAAAGA
>5.11|1442997|33|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCTTTAATATACGCCAAACGTTGCGTTTTGCAA
>5.12|1443060|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GAAAGCGGCCGCCGGGCCGCCCTTGCTTTTCCCAGT
>5.13|1443126|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AAACTGCCCCGACCTGCGGAACGATTGCATTCCCCG
>5.14|1443192|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TGCCATCTGGCGCGTGCTGGAGCGGCGCTGGCGAAG
>5.15|1443258|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GTCTGATTGTCGTGGACTATCTGCAACTGCTCCTTC
>5.16|1443324|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CAGGACGTGCCGCTTTTCAATTACGTGCTGAAACAG
>5.17|1443390|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CCGCACGATCGCATCGCTGTCATAGTCGGAAAAACAC
>5.18|1443457|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GCAATTTGGCTCACTCAGTCATCGTCACAACTTCTT
>5.19|1443523|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
GAAGAAATGGTGAAGAACGATTACTACCGGTTTGAAC
>5.20|1443590|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CCAACCGGGTTCTGGACCGCTGGGGCGAGGAGTACAA
>5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TCCGGCGGCAATCACGCCGTCCACATCGAACCCGCCGC
>5.22|1443725|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CGATATTTACGAGCTAACTTTGCATTATTTAGCTTC
>5.23|1443791|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AGGTCGATGCTCGAAGTCTGGATCGAGCATGAAGCGT
>5.24|1443858|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
TATTCCTCGACGATCGATCCCTCACGCTTGTACACC
>5.25|1443924|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AGGCCAGCTCTCCGCACCTTCAGCGGGGCGTGACGA
>5.26|1443990|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CATTCGCCAGATGCTTCGCCAGCCCCATCTCAGCA
>5.27|1444055|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
AGGACACGTTCACCTGTACCGACTTCAGGCCCGAGC
>5.28|1444121|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CAACTGCTGCGCAAGAGCGTCGGGGCACCGGCCCGC
>5.29|1444187|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT
CTCCTCGAGTTCGATGTCCTCATCCTCCCTTTGCAGA

CRISPR arrays and Neighbor proteins around NC_015966_5

CRISPR arrays

The CRISPR arrays of NC_015966_5

>merge|NC_015966|5|1442301-1444253|PILER-CR,CRISPRCasFinder,CRT
ATTTCAATACCAAAAAGGTGCGATTAAAACCATGAGCGAGCCATTCCCATTCGTCACCGAGATCTGAATTTCAATACCAAAAAGGTGCGATTAAAACAGCGCCCGCATCCGGTTGCGTACAGCCACACTCGTTTATTTCAATACCAAAAAGGTGCGATTAAAACCCTGGAAGTTCATCCATCACATGGTCAGCGAAGATATTTCAATACCAAAAAGGTGCGATTAAAACTTGGTCGTAATGCTCCAACCGCCAATCGTGCCTGATGATTTCAATACCAAAAAGGTGCGATTAAAACAGTTAGAAAAGGTAGCCCAGGAAAGGGGCTTTAGGATTTCAATACCAAAAAGGTGCGATTAAAACATGCTGCCTTTGACTGTGATCTGCACGGTGCATATAGACATTTCAATACCAAAAAGGTGCGATTAAAACGTCCTTCGGTAGAGCGTTTGGTGCCGGTAGAACGTCATTTCAATACCAAAAAGGTGCGATTAAAACTCGGACCAGACGGCGCCCCAGTCCTCGTATACAAGGAATTTCAATACCAAAAAGGTGCGATTAAAACTTGCTATATATCATATTTCACGCGTTCGCTTTCGAAGTATTTCAATACCAAAAAGGTGCGATTAAAACAAGGACGCAGTACTTCGATAGGCCTTCGTCAAAGAATTTCAATACCAAAAAGGTGCGATTAAAACGCTTTAATATACGCCAAACGTTGCGTTTTGCAAATTTCAATACCAAAAAGGTGCGATTAAAACGAAAGCGGCCGCCGGGCCGCCCTTGCTTTTCCCAGTATTTCAATACCAAAAAGGTGCGATTAAAACAAACTGCCCCGACCTGCGGAACGATTGCATTCCCCGATTTCAATACCAAAAAGGTGCGATTAAAACTGCCATCTGGCGCGTGCTGGAGCGGCGCTGGCGAAGATTTCAATACCAAAAAGGTGCGATTAAAACGTCTGATTGTCGTGGACTATCTGCAACTGCTCCTTCATTTCAATACCAAAAAGGTGCGATTAAAACCAGGACGTGCCGCTTTTCAATTACGTGCTGAAACAGATTTCAATACCAAAAAGGTGCGATTAAAACCCGCACGATCGCATCGCTGTCATAGTCGGAAAAACACATTTCAATACCAAAAAGGTGCGATTAAAACGCAATTTGGCTCACTCAGTCATCGTCACAACTTCTTATTTCAATACCAAAAAGGTGCGATTAAAACGAAGAAATGGTGAAGAACGATTACTACCGGTTTGAACATTTCAATACCAAAAAGGTGCGATTAAAACCCAACCGGGTTCTGGACCGCTGGGGCGAGGAGTACAAATTTCAATACCAAAAAGGTGCGATTAAAACTCCGGCGGCAATCACGCCGTCCACATCGAACCCGCCGCATTTCAATACCAAAAAGGTGCGATTAAAACCGATATTTACGAGCTAACTTTGCATTATTTAGCTTCATTTCAATACCAAAAAGGTGCGATTAAAACAGGTCGATGCTCGAAGTCTGGATCGAGCATGAAGCGTATTTCAATACCAAAAAGGTGCGATTAAAACTATTCCTCGACGATCGATCCCTCACGCTTGTACACCATTTCAATACCAAAAAGGTGCGATTAAAACAGGCCAGCTCTCCGCACCTTCAGCGGGGCGTGACGAATTTCAATACCAAAAAGGTGCGATTAAAACCATTCGCCAGATGCTTCGCCAGCCCCATCTCAGCAATTTCAATACCAAAAAGGTGCGATTAAAACAGGACACGTTCACCTGTACCGACTTCAGGCCCGAGCATTTCAATACCAAAAAGGTGCGATTAAAACCAACTGCTGCGCAAGAGCGTCGGGGCACCGGCCCGCATTTCAATACCAAAAAGGTGCGATTAAAACCTCCTCGAGTTCGATGTCCTCATCCTCCCTTTGCAGAATTTCAATACCAAAAAGGTGCGATTAAAAC

>NC_015966|5|2|1442301-1444253|PILER-CR
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CATGAGCGAGCCATTCCCATTCGTCACCGAGATCTGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGCGCCCGCATCCGGTTGCGTACAGCCACACTCGTTT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCTGGAAGTTCATCCATCACATGGTCAGCGAAGAT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TTGGTCGTAATGCTCCAACCGCCAATCGTGCCTGATG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGTTAGAAAAGGTAGCCCAGGAAAGGGGCTTTAGG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	ATGCTGCCTTTGACTGTGATCTGCACGGTGCATATAGAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTCCTTCGGTAGAGCGTTTGGTGCCGGTAGAACGTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TCGGACCAGACGGCGCCCCAGTCCTCGTATACAAGGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TTGCTATATATCATATTTCACGCGTTCGCTTTCGAAGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AAGGACGCAGTACTTCGATAGGCCTTCGTCAAAGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCTTTAATATACGCCAAACGTTGCGTTTTGCAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GAAAGCGGCCGCCGGGCCGCCCTTGCTTTTCCCAGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AAACTGCCCCGACCTGCGGAACGATTGCATTCCCCG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TGCCATCTGGCGCGTGCTGGAGCGGCGCTGGCGAAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTCTGATTGTCGTGGACTATCTGCAACTGCTCCTTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CAGGACGTGCCGCTTTTCAATTACGTGCTGAAACAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCGCACGATCGCATCGCTGTCATAGTCGGAAAAACAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCAATTTGGCTCACTCAGTCATCGTCACAACTTCTT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GAAGAAATGGTGAAGAACGATTACTACCGGTTTGAAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCAACCGGGTTCTGGACCGCTGGGGCGAGGAGTACAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TCCGGCGGCAATCACGCCGTCCACATCGAACCCGCCGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CGATATTTACGAGCTAACTTTGCATTATTTAGCTTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGTCGATGCTCGAAGTCTGGATCGAGCATGAAGCGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TATTCCTCGACGATCGATCCCTCACGCTTGTACACC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGCCAGCTCTCCGCACCTTCAGCGGGGCGTGACGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CATTCGCCAGATGCTTCGCCAGCCCCATCTCAGCA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGACACGTTCACCTGTACCGACTTCAGGCCCGAGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CAACTGCTGCGCAAGAGCGTCGGGGCACCGGCCCGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CTCCTCGAGTTCGATGTCCTCATCCTCCCTTTGCAGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC

>NC_015966|5|5|1442301-1444253|CRISPRCasFinder
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CATGAGCGAGCCATTCCCATTCGTCACCGAGATCTGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGCGCCCGCATCCGGTTGCGTACAGCCACACTCGTTT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCTGGAAGTTCATCCATCACATGGTCAGCGAAGAT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TTGGTCGTAATGCTCCAACCGCCAATCGTGCCTGATG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGTTAGAAAAGGTAGCCCAGGAAAGGGGCTTTAGG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	ATGCTGCCTTTGACTGTGATCTGCACGGTGCATATAGAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTCCTTCGGTAGAGCGTTTGGTGCCGGTAGAACGTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TCGGACCAGACGGCGCCCCAGTCCTCGTATACAAGGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TTGCTATATATCATATTTCACGCGTTCGCTTTCGAAGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AAGGACGCAGTACTTCGATAGGCCTTCGTCAAAGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCTTTAATATACGCCAAACGTTGCGTTTTGCAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GAAAGCGGCCGCCGGGCCGCCCTTGCTTTTCCCAGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AAACTGCCCCGACCTGCGGAACGATTGCATTCCCCG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TGCCATCTGGCGCGTGCTGGAGCGGCGCTGGCGAAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTCTGATTGTCGTGGACTATCTGCAACTGCTCCTTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CAGGACGTGCCGCTTTTCAATTACGTGCTGAAACAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCGCACGATCGCATCGCTGTCATAGTCGGAAAAACAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCAATTTGGCTCACTCAGTCATCGTCACAACTTCTT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GAAGAAATGGTGAAGAACGATTACTACCGGTTTGAAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCAACCGGGTTCTGGACCGCTGGGGCGAGGAGTACAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TCCGGCGGCAATCACGCCGTCCACATCGAACCCGCCGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CGATATTTACGAGCTAACTTTGCATTATTTAGCTTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGTCGATGCTCGAAGTCTGGATCGAGCATGAAGCGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TATTCCTCGACGATCGATCCCTCACGCTTGTACACC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGCCAGCTCTCCGCACCTTCAGCGGGGCGTGACGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CATTCGCCAGATGCTTCGCCAGCCCCATCTCAGCA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGACACGTTCACCTGTACCGACTTCAGGCCCGAGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CAACTGCTGCGCAAGAGCGTCGGGGCACCGGCCCGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CTCCTCGAGTTCGATGTCCTCATCCTCCCTTTGCAGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC

>NC_015966|5|2|1442301-1444253|CRT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CATGAGCGAGCCATTCCCATTCGTCACCGAGATCTGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGCGCCCGCATCCGGTTGCGTACAGCCACACTCGTTT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCTGGAAGTTCATCCATCACATGGTCAGCGAAGAT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TTGGTCGTAATGCTCCAACCGCCAATCGTGCCTGATG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGTTAGAAAAGGTAGCCCAGGAAAGGGGCTTTAGG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	ATGCTGCCTTTGACTGTGATCTGCACGGTGCATATAGAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTCCTTCGGTAGAGCGTTTGGTGCCGGTAGAACGTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TCGGACCAGACGGCGCCCCAGTCCTCGTATACAAGGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TTGCTATATATCATATTTCACGCGTTCGCTTTCGAAGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AAGGACGCAGTACTTCGATAGGCCTTCGTCAAAGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCTTTAATATACGCCAAACGTTGCGTTTTGCAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GAAAGCGGCCGCCGGGCCGCCCTTGCTTTTCCCAGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AAACTGCCCCGACCTGCGGAACGATTGCATTCCCCG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TGCCATCTGGCGCGTGCTGGAGCGGCGCTGGCGAAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTCTGATTGTCGTGGACTATCTGCAACTGCTCCTTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CAGGACGTGCCGCTTTTCAATTACGTGCTGAAACAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCGCACGATCGCATCGCTGTCATAGTCGGAAAAACAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCAATTTGGCTCACTCAGTCATCGTCACAACTTCTT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GAAGAAATGGTGAAGAACGATTACTACCGGTTTGAAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CCAACCGGGTTCTGGACCGCTGGGGCGAGGAGTACAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TCCGGCGGCAATCACGCCGTCCACATCGAACCCGCCGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CGATATTTACGAGCTAACTTTGCATTATTTAGCTTC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGTCGATGCTCGAAGTCTGGATCGAGCATGAAGCGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TATTCCTCGACGATCGATCCCTCACGCTTGTACACC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGCCAGCTCTCCGCACCTTCAGCGGGGCGTGACGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CATTCGCCAGATGCTTCGCCAGCCCCATCTCAGCA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGGACACGTTCACCTGTACCGACTTCAGGCCCGAGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CAACTGCTGCGCAAGAGCGTCGGGGCACCGGCCCGC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CTCCTCGAGTTCGATGTCCTCATCCTCCCTTTGCAGA
ATTTCAATACCAAAAAGGTGCGATTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_014066865.1|1448250_1449147_+|GlcNAc-PI-de-N-acetylase	unknown	unknown	gnl|CDD|274915
NC_015966.1|WP_014066868.1|1450824_1452018_+|hypothetical-protein	unknown	unknown	gnl|CDD|237556
NC_015966.1|WP_014066862.1|1444518_1445838_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl|CDD|236486
NC_015966.1|WP_014066858.1|1434515_1435817_+|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl|CDD|234856
NC_015966.1|WP_014066866.1|1449152_1449629_-|fucose-permease	unknown	unknown	gnl|CDD|340952
NC_015966.1|WP_155815976.1|1452115_1453015_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379173
NC_015966.1|WP_014066856.1|1430061_1431027_-|1,2-phenylacetyl-CoA-epoxidase-subunit-A	unknown	unknown	gnl|CDD|184320
NC_015966.1|WP_014066860.1|1437045_1440516_+|hypothetical-protein	unknown	unknown	gnl|CDD|275042
NC_015966.1|WP_012844039.1|1433903_1434473_+|gamma-carbonic-anhydrase-family-protein	unknown	unknown	gnl|CDD|100051
NC_015966.1|WP_014066871.1|1455243_1455510_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|198034
NC_015966.1|WP_014066867.1|1449632_1450403_-|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl|CDD|238693
NC_015966.1|WP_014066855.1|1429775_1430069_-|1,2-phenylacetyl-CoA-epoxidase-subunit-B	unknown	unknown	gnl|CDD|368813
NC_015966.1|WP_012844036.1|1436609_1436819_-|hypothetical-protein	unknown	unknown	gnl|CDD|376675
NC_015966.1|WP_014066857.1|1431217_1433914_+|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl|CDD|235444
NC_015966.1|WP_014066861.1|1440525_1442196_-|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|223733
NC_015966.1|WP_155815975.1|1435833_1436637_+|hypothetical-protein	unknown	unknown	gnl|CDD|271333
NC_015966.1|WP_014066870.1|1453035_1455174_+|DNA-ligase-(NAD(+))-LigA	unknown	unknown	gnl|CDD|236137
NC_015966.1|WP_014066864.1|1447205_1448243_+|class-1-fructose-bisphosphatase	unknown	unknown	gnl|CDD|236458
NC_015966.1|WP_014066863.1|1445945_1447118_+|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029
NC_015966.1|WP_014066854.1|1428983_1429766_-|phenylacetate-CoA-oxygenase-subunit-PaaC	unknown	unknown	gnl|CDD|368300

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_014066865.1|1448250_1449147_+|GlcNAc-PI-de-N-acetylase	gnl|CDD|274915	TIGR04001, thiol_BshB1, bacillithiol biosynthesis deacetylase BshB1. Members of this protein family are BshB1 (YpjG), an enzyme of bacillithiol biosynthesis; either BshB1 or BshB2 (YojG) must be present, and often both are present. Bacillithiol is a low-molecular-weight thiol, an analog of glutathione and mycothiol, and is found largely in the Firmicutes. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	3.02114e-37
NC_015966.1|WP_014066868.1|1450824_1452018_+|hypothetical-protein	gnl|CDD|237556	PRK13915, PRK13915, putative glucosyl-3-phosphoglycerate synthase; Provisional.	7.11501e-05
NC_015966.1|WP_014066862.1|1444518_1445838_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl|CDD|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NC_015966.1|WP_014066858.1|1434515_1435817_+|phosphoribosylamine--glycine-ligase	gnl|CDD|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NC_015966.1|WP_014066866.1|1449152_1449629_-|fucose-permease	gnl|CDD|340952	cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.21748e-20
NC_015966.1|WP_155815976.1|1452115_1453015_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379173	pfam13413, HTH_25, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	2.80289e-11
NC_015966.1|WP_014066856.1|1430061_1431027_-|1,2-phenylacetyl-CoA-epoxidase-subunit-A	gnl|CDD|184320	PRK13778, paaA, phenylacetate-CoA oxygenase subunit PaaA; Provisional.	0
NC_015966.1|WP_014066860.1|1437045_1440516_+|hypothetical-protein	gnl|CDD|275042	TIGR04189, gliding_motility-related_protein, cell surface protein SprA. SprA is a cell surface protein widely distributed in the Bacteroidetes lineage. In Flavobacterium johnsoniae, a species that shows gliding motility, mutation disrupts gliding.	1.54933e-06
NC_015966.1|WP_012844039.1|1433903_1434473_+|gamma-carbonic-anhydrase-family-protein	gnl|CDD|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	2.89606e-82
NC_015966.1|WP_014066871.1|1455243_1455510_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl|CDD|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	1.20615e-10
NC_015966.1|WP_014066867.1|1449632_1450403_-|glucosamine-6-phosphate-deaminase	gnl|CDD|238693	cd01399, GlcN6P_deaminase, GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.	2.00971e-143
NC_015966.1|WP_014066855.1|1429775_1430069_-|1,2-phenylacetyl-CoA-epoxidase-subunit-B	gnl|CDD|368813	pfam06243, PaaB, Phenylacetic acid degradation B. Phenylacetic acid degradation protein B (PaaB) is thought to be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation.	2.82764e-46
NC_015966.1|WP_012844036.1|1436609_1436819_-|hypothetical-protein	gnl|CDD|376675	pfam01941, AdoMet_Synthase, S-adenosylmethionine synthetase (AdoMet synthetase). This family consists of several archaebacterial S-adenosylmethionine synthetase C(AdoMet synthetase or MAT) (EC 2.5.1.6). S-Adenosylmethionine (AdoMet) occupies a central role in the metabolism of all cells. The biological roles of AdoMet include acting as the primary methyl group donor, as a precursor to the polyamines, and as a progenitor of a 5'-deoxyadenosyl radical. S-Adenosylmethionine synthetase catalyzes the only known route of AdoMet biosynthesis. The synthetic process occurs in a unique reaction in which the complete triphosphate chain is displaced from ATP and a sulfonium ion formed. MATs from various organisms contain ~400-amino acid polypeptide chains.	0.0077985
NC_015966.1|WP_014066857.1|1431217_1433914_+|DNA-mismatch-repair-protein-MutS	gnl|CDD|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NC_015966.1|WP_014066861.1|1440525_1442196_-|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	7.03103e-150
NC_015966.1|WP_155815975.1|1435833_1436637_+|hypothetical-protein	gnl|CDD|271333	cd14963, NHL_like_5, Uncharacterized NHL-repeat domain in bacterial proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	3.55619e-19
NC_015966.1|WP_014066870.1|1453035_1455174_+|DNA-ligase-(NAD(+))-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_015966.1|WP_014066864.1|1447205_1448243_+|class-1-fructose-bisphosphatase	gnl|CDD|236458	PRK09293, PRK09293, class 1 fructose-bisphosphatase.	0
NC_015966.1|WP_014066863.1|1445945_1447118_+|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	0
NC_015966.1|WP_014066854.1|1428983_1429766_-|phenylacetate-CoA-oxygenase-subunit-PaaC	gnl|CDD|368300	pfam05138, PaaA_PaaC, Phenylacetic acid catabolic protein. This family includes proteins such as PaaA and PaaC that are part of a catabolic pathway of phenylacetic acid. These proteins may form part of a dioxygenase complex.	1.07537e-119

Protein sequences

>NC_015966.1|WP_014066861.1|1440525_1442196_-|AarF/ABC1/UbiB-kinase-family-protein
MPPAVATRARRARQIAEVLLRHGLGYLVSIFGLERFVPLHRGLLGHPRRPEPYAAPEHLRMALEELGAAWIKLGQFLATRADLLPPSYQRELARLQDAAAPVPGAQIQAVIEAELGRPVSELFARFEPEPLAAASIGQAHAATLPDGTEVVVKVRRPGVVEQVEQDLELLLTLAHTASRHWELAETYDIVGIVQEFALTLRAELDYLREGRNAERFAHNFAGNPAVHIPRVFWEYTTSRVLTLERIRGIKIDNLTALDAAGFDRTELAERVARILMQMVFEDGFFHADPHPGNFFVEPDGTIGLIDFGMVGIVDAPTQDRLAQLLLALAQQDPDRLVDAFLELGVARRYVDRLALREDLRHFVLSYYDRPLRELRLEPLLKEALAIVRRHHLHLPTNLVLLAKTVMMAEGLAARLAPDFQVATLLPGYVRRLLLHRYLPLRWIRRLSWTGLEAAEFGLELPRQLRRLLHALEQGSLQLGMRPEGFEPLIARLERLTNRLVLGMITAAFIVGLAVLMTAFRLPGIEPLIGPLFGLGFLLTALLAAYLIWVILRSGQI
>NC_015966.1|WP_014066860.1|1437045_1440516_+|hypothetical-protein
MRRWPGLVGWVLLLGTIAPARGQTFPGTVAWQDTLQVGTTRVFVLRPFMLLRTVQVWLDDQPLDSTAYRLDAAQGVLVLADSLQGDRLVVAYRTLPLDVPPVYQLYRARSLPPTAAIPADPPRRNTSASDPPFASGLQPRGRITRGIVTGNRQDVSIASALQLELSGEVAEGVTLEALLSDADVPLSPEGTTQRLREFDRIYVRLQTRSGHVQLGDYDLKLGEETLFGVQRKLQGALLAAQLPGAGPVRRLTIQASGAVSKGIYRRQTIVPVEGVQGPYRLTGAAGEPFVLVLPGSERVYLDGRLLDRGTDYVIDYATGELTFTPRHLITAERRISVEFEYTAGNGTRSLLASQAHLELGRSRPVAFLEVAALREADGRRFGETFGLTRADSLALRQAGDGLAVRSGAEQVPFDPEAPYVLYTREVRMLPDGTTDTVYVALTSAPPPGTPVYRVTFSRVGPGRGRYVRAGQTVNGIVYVYRGPGQGDYEPVRLLPTPVRHDLVGLRAGIHPRPGWTLGGEWARSRYDANRLSPLDAADDLAGAYRLFLRIDSLTLPVGRLAASLRRQHLDAHFAAFDRLQPVEFARRWNLNVRDLAENSGAFVQPVAETADEAYLTWRAGRSGAIDLELGRLRRPGQFRGERQALGLTLGRETSAQLRYDGELIRSRHETTGERGRWLRQEGRLTVPLGAGLTPYVAALHEDRRQQALHADSLHADSPAYLEVRPGLVWQRSALQADVSLAWRREADVWQGRRLPSGRIWTLQGRLQYTPGPHFGTTTELGYRRRRTPPRFAARYPLDQTLALHWDGFFRSPGRLLGLNWRYGVQSERAPVLQEVYVRTGPEFGQYVWEDFNGDGLPQVDEFVPETLPDEGVYERVLVPSDSLTAATSVEARLQLELTPGHRWEALRPLSLRTTVTLRDRTQDPALGRLLGLDPAHLLTTATLDGQLRVTQDLYLWRGHPDHSLTLSLVGVRTLARRATGRETRRMQQGHLAVRYRVADPWVLDLQAEVQRDHQTSEGLSGRTYRLRRYRTRLGLERAIGSGRAGGAVEVAHGRTVPQPLRLWTIRLPLEAELARPGRERMRLRFEPAHVWQQGTGGGLAAYLLTEGLSPGWNATWGVELERTLSGNLELTLGYHGRLRTAAPFRHTLRAELSAVF
>NC_015966.1|WP_012844036.1|1436609_1436819_-|hypothetical-protein
MRIDVGEQALKAAEQHIQENLRFLQAHVRSLKDRMRALRKANLLTPRRKYKIVAEILSTTAYLRPGADN
>NC_015966.1|WP_155815975.1|1435833_1436637_+|hypothetical-protein
MLGASLAAAQTPDTLHLEPRAAFVEGRALDVDPTGRLYVADAARHVVVRLTPEGHVEEELGGPGGAPGRFDTPVAVDARAGLSFWVAEAGSRRLQRLTRQGMSLEIAALPDGVSPIAVRWLGRWLFVLDVAGGRLWRRGPDGNWQVVGGTGIDEPLQAPVALAVGPGDRLLVADAARRVVLAYDRRGTFERIWTPTLPGTPRALAAQGDTLWMVLDRKLVRYLPDGRLETVGQLSFDVVGLVWEGRRGWLLSRQRLYRAQLSAPGRR
>NC_015966.1|WP_014066858.1|1434515_1435817_+|phosphoribosylamine--glycine-ligase
MRILVLGSGGREHAITWALAQSPQRPDLFIAPGNPGTAALGRNVPIAANDAANLRKLVRDEGIELVVVGPEQPLVEGVADALRAEGARVVGPSAAAARLEGSKAFAKAFMQRHGIPTAAYRTFAAEQLDEALAYIDRHPEPLVVKASGLAAGKGAVVCATREEARRTLRWMMEEGGLGKAGHEVVIEEFMEGEEASVFALTDGRDYVLLAPAQDHKRIGEGDTGPNTGGMGAYAPAPVVTEAVLERVAREIVEPVLAGMADEGHPYQGVLYCGLMITDEGPKVVEFNCRLGDPEAQVVLPVAEVDWVEVFDRVASGQVAGFSVPPARRAAACVVLASEGYPGSYRKGLPIEGLEAAEALPDVIVFQAGTRRADDGRLVTAGGRVLGVTAVAESLAAAIRRAYEGVEVIQFEGKYFRRDIGQKGLARLATAGSV
>NC_015966.1|WP_012844039.1|1433903_1434473_+|gamma-carbonic-anhydrase-family-protein
MIRDFLGAYPRFDATNFIAPNAVVIGDVTLEPYASIWYGAVVRADVNWIRIGEASNIQDGAIIHVTRGTAPTLIGPRVTVGHGAVLHGCTVEENVLIGIGAVVLDGAVIGRDTIIGARALVPPGMKVPPRSLVLGVPGRVVRTLTDEEVAGIARYAQNYLEYSAIYRGEVQPERNPFYDPSETPDGHSG
>NC_015966.1|WP_014066857.1|1431217_1433914_+|DNA-mismatch-repair-protein-MutS
MASREAEKQVGQTPLMRQYYKIKSRYPNAILLFRMGDFYETFDEDAHIVSRVLGITLTKRSNGQAADVPLAGFPHHALDNYLPKLVRAGYRVAICEQLEDPKFARKVVKRDVVEVVTPGVSFHEHLLDPKRANYLAAVVWGTERGERDRIGFAFLDASTGEFSVTEAPAHRLEDLLQTIQPAEVLVDKRQRDRLQSVRGLSFVVTPQEDWVFNFDYAYEVLLRHFKTHSLKGFGVDDLRLGLRAAGAALHYLGETQKGRLPHVRRLTRYVTDEYMVLDPQTKRNLELVASLQDGTQEGSLVQILDETLTPMGGRLLRRWLLRPLKNVRQIEKRLEAVEALVRDRRLRERLREELRQVGDLERLAARVCTGRATPRDLMHLRLTLEQIPPIKQALADVSCDTLRRLAEQLTLCTQVVERIRQALVDDPPASLSDGGVIRDGFSAELDELREIARSGKDFIARLQQKEIERTGIPSLKVGFNKVFGYYIEVTNAHRNKIPPHYIRKQTLVNAERYITPELKEYEEKILSAEEKIASLEAELFNRLRLEVAEATAELQLNASLLAMLDVFCSLAEVADRYGYTRPELHEGTELLIEEGRHPVVERTLPPGEPFIPNDIYLDTHAQQILIITGPNMAGKSVVLRQTGLIVLLAQIGSFVPARRARIGIVDRIFTRVGASDNLAAGESTFLVEMNETANILNNATPRSLILLDEVGRGTSTFDGLSIAWALVEYLHETPSVAARTLFATHYHELNELAERFPRVKNFRVQVEEHDGRVIFLHKLVPGGADHSYGIEVARMAGLPEPVIARAREILRHLEAQHLVVEAPAGDGEPVRPVRARRAERIPADTSAFQLSLFAQPEPDPVAEELKERLRRIDPNRMTPIEALLLLDELKRLVERHDS
>NC_015966.1|WP_014066856.1|1430061_1431027_-|1,2-phenylacetyl-CoA-epoxidase-subunit-A
MKDEALLEAEFQARIDAGEKIEPKDWMPERYRRQLIRMMSQHAHSEIVGMLPEGNWITRAPTLRRKMALLAKVQDEAGHGLYLYSATETLGVDRYQLIRDLLEGRAKYSNIFNYPTLTWADVGVIGWFVDGAAIVNQTMLAKSSYGPYARAMIRICKEEAFHKRQGYEICVTLARGTPEQRRMLQDAINRWWWPTLMMFGPPDDQSPNSAELLRWQVKRKTNDELRQHFINITVPQVLALGMTLPDPELRYDEKTGNWLIGPIDWDEFWRVIRGHGPCNRERLQARRKAHEEGAWVREAVQAYARKRQQQAASTAAEVSHG
>NC_015966.1|WP_014066855.1|1429775_1430069_-|1,2-phenylacetyl-CoA-epoxidase-subunit-B
MAEMENCMRLWEVFVQPRTGAPHEHAGSVRATHAEMALQHARDVYARRGPVVSIWVVPTDAIYATRPGDEGPFFDPADSKPYRHPLFYKVPHGVKNI
>NC_015966.1|WP_014066854.1|1428983_1429766_-|phenylacetate-CoA-oxygenase-subunit-PaaC
MTLETLDAALRPTLFEYLLRLGDDALILGHRLSEWCGHGPYLEEDIALANLALDCLGHAEALLTLAGEVEGKGRTADDLAFLRDAYDFRNVQMVELPRGDFAFTITRQFLFAAYACLLYEALQQSAFEPLAGIAAKALKEMRYHLRHSSEWMRCLGDGTEESHRRAQTALDELWMYTGELFEVDDTLRTLTEARVAPDMAALQPKWREQVEAVIHEATLTVPEDPPYMATGGRRGHHTEHLGHLLAEMQFLQRAYPGAQW
>NC_015966.1|WP_014066862.1|1444518_1445838_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MDKLVIEGGRPLRGTIPISGSKNTALMLMAGAVLADGVTVLENIPHLRDITTFSHVLRIAGASVRFDPETHVMRIDATRIDFPEAPYELVKQMRASFYMLGALLGRCGQARVSLPGGCAWGPRPVNLHLEGLRAFGAEIELDRGYVVARAPGGRLRGGRFRLDPPSVGATVNLLLGAVTARGSSRIENAALEPDVVVFGRALQQMGARIEGLGTRTIEVEGVDALQPITFRNCPDRIELGTFMIASALAGTPGDTIYLTGAEPSHLGEAFLEAFRQTGAAFTFDGDTVAVSVPERLQAVSIETAPYPGFPTDLQAQWTVLLSRAEGAGFVRDTVYPDRFKHVPELMRMGLQARVEGNTVFLEGPQRLQGAHVMSTDLRGSVSLVLAGLVAEGETHVLRVYHLDRGYENLEGKLSAAGIAIRRESYDEFATPASESAEES
>NC_015966.1|WP_014066863.1|1445945_1447118_+|cysteine-desulfurase
MRKPEIIYLDHAATTPLDPRVLEAMRPYLEEHYGNPSSVHQLGRRARVAIEESRERIAALIGAEPAEIVFTSGGTEADNLALRGVLHGTRRHLITSLAEHEAILRTAEALEEEGAAVTYLRPGPDGAVTAEQVAEALTEKTGLVSIMHTNNELGTCSPVRAVAEVCHRRGVPLHCDAVQAVGLLPVRVDELGVDLLSASAHKFYGPKGVGFLYVRRGIELRPLLRGGKQEQGRRAGTENVAAIVGMARALELAVEEQEARLNHLRRLRERLIRRLDEALGGMFVLNTPRDPERAAPHIVNIAFPPQNGEPVDGEMLLLNLDLEGVCVSSGSACTSGAVEPSHVLRAIGLPRETAGAAVRFSMGWKNTEAEIDRAVEILAAVMARLAGVLR
>NC_015966.1|WP_014066864.1|1447205_1448243_+|class-1-fructose-bisphosphatase
METLHTRGRKVVEEFITLEQFIIDQQERFPHSTGAFSRLLRDISVAAKIVNRDIRRAGLVDIFGTTGKVNIHGEVQQKLDALAHEEFVRALRRGGECCLIGSEEHAEAIPLSANGEGDGRYIVLLDPLDGSSNVDVNVSVGTIFSIYRLPDEYETPTLEAALQPGSKQVAAGYIVYGSSTMLVYTTGDGVNGFTLDPSIGEFILSHPNIRIPKTGSIYSINEGNFNSFEEGLKRFIRWAQEEDKATGRPFSTRYIGSFVSDFHRNLLKGGIYMYPATKKNPEGKLRLMYEANPMAFIVEQAGGRASDGHRRILDIVPEKLHQRTPLFIGSEELVRTVEEFLQGKR
>NC_015966.1|WP_014066865.1|1448250_1449147_+|GlcNAc-PI-de-N-acetylase
MRGSGLFLLTGILLLVMAVSVQAQSARPLRILCIGAHPDDCDVKMGGTAALFAAMGHQVKFLSVTNGDAGHYAQGGGVLAKRRRAEAEEAARRLGIAEYEVLDNHDAELVPSLEVRKQIIRKIREWQADLVFAPRPNDYHPDHRYTGQLVQDAAYLVMVPNVVPDTPPLAHNPVFLYLSDRFKKPSPFSPDIAVIIDSVIERKLDALDAHVSQFYEWLPWIDGRLAEVPADSAARREWLRAQWIRPNITQEVRLALMRWYDPEVAARAQYVEAFEICEYGHQPTEDEIRLLFPMLGKP
>NC_015966.1|WP_014066866.1|1449152_1449629_-|fucose-permease
MRQRSYALVGLILFTFFVISFLTNIIGPLIPEIIDDFGLSLTLAALGCLTAALLGPGPVARWAFPLIGLFASVMWPVVFSLALNSVEAHHGAFSGILVTGIAGGAVVPLVIGTLGDLLGLRGGLCFLYLTFGYILSVSFWARPLIPNKTIWRREAPAS
>NC_015966.1|WP_014066867.1|1449632_1450403_-|glucosamine-6-phosphate-deaminase
MLVEIFPDYETLSERAYEIVATLIRRKPNCVLGFATGSTPLGLYRRLVEGYRRGELDFSKVVTFNLDEYVGLPPSHPQSYHHFMWENLFQHININPSNVHLPNGMVDDIEVHCDWYEEQIRRAGGIDLQILGIGPNGHLAFNEPGSSLGSRTRIKTLSQATRRANARFFGSEEAVPRHAITMGIGTIMEARRLLLLASGRAKARAVRAMLEGPISAMVSATIVQLHRYAHVLLDAEAASELAYNHHDGISEPFDVH
>NC_015966.1|WP_014066868.1|1450824_1452018_+|hypothetical-protein
MSLVVFPFKHEHPEVLLHNVRVAAAHPRVHEVLCIGYEREQTYEAVERAAPEISRATGTPVSVRLQERLGTLRPGKGDGMNTALRYFLEETRWERIHFYDADITSFGPDWITKAEEAADFGYGLVRHYFPRASTDAMITWMITRTGFALLWPHTELSWIEQPLGGELLMRREVAAMLYEDERVRRRSDWGIDTLYTFVTVQQGVSIYECYIPEGKAHRLYGGLDDLRTMLVECFAVIQSLQHEVVGQPAIHRQEHPHRVPVHIAERVGYDVEATLHRLMQHWTPRQVELLELFTTPVREGLRTCQRRPAFNFMDEMAWAATYHVLLEHFQPGDPDWEELLFKLWTTRVLNYTMTVALRGYDYAQQYLYRMLGRYRYQAALENGRGHPVPPRAALSTA
>NC_015966.1|WP_155815976.1|1452115_1453015_+|helix-turn-helix-domain-containing-protein
MRRLAHDLRRIREKQKRSLQEIHNETKIALELLQHFERTALYDHERYNPVYLRSFARTYASAIGIDPAAVLDAVELAFEGRYRNQLAVRFLGEEPLPEPEPETAPAEASTPEAAPERKPPQESETPLPLVSTPGGLERLERPARWKARVVGVIVVVMAAAGIWYLLRPAPAPPPEPLPVDTATVPATATDTTPSVEAPPVQVPVLGDTITATVIAAFDKVDPIRVRIDRDLRRPYWIEQGDSMQFRFTERIILENQLDDIQLRLDGHPYPTDRRDAEGRIVITREQLQAYLDSLARGVQ
>NC_015966.1|WP_014066870.1|1453035_1455174_+|DNA-ligase-(NAD(+))-LigA
METHTAPQTAEARLLEATHALLQTVRQRDLEAIDRKEAEALAARLREVLNQHAYRYYVLDNPLIPDADYDLLMQALRKLEARFPELVTPDSPTQRVGGPPLGRFEKVRHPEPLLSLNNAFGEEDVRAWYERCCRMLAERLGHPVQPAVTAELKIDGLAMALTYENGVLTVGATRGDGIEGENVTQNVRTIPAIPLRIPVDPSIGPPPARLEVRGEVYMRKRDFERLNAQLQARGERPFANPRNAAAGSVRQLNPQVTASRPLSFFAYGIGPVEGAEVPDSQYEVLQWLGRLGFPVNEHARRFERLDDVLEYCRYWTEHRDELDYEIDGVVLKIDHRPWQALLGAISNAPRWAVAYKFPAREAITRLLDIMVSVGRTGVVKPVAVLEPVEVGGVTVSQATLHNEDYVRSRDIRIGDLVVVIRAGDVIPQVVRPVVEARTGNERPWRMPERCPSCGSQLVRLPGEADYYCVASDCPAQFVRLLEHFASRDAMDIEGMGSQVARQLAESGLVRRLSDLYRLKLEDLLKLEGFAETRARNLLRAIEASKRRPLSRLLFGLGIRHVGKTTAELLVQRFASIDELAAATIDELAALEGVGPITAESIANWFRVEDNRRLIEELKELGVNTQRLPEEAPAAESPVRGKTFVLTGALPHLTRKEAEELIKRAGGRVASSVSRNTDYVVVGENPGSKYDRARQLGIPMLDEDGLLRLLGMK
>NC_015966.1|WP_014066871.1|1455243_1455510_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKTTVRLTRKGQITVPRQVRETLGLHAGDEIELSVEDGKIVIRPVRRYSVDELLKLLPGSPTSYPGEVAEKAAIVQELARKEHRIRDR

Crispr_ID: NC_015966_6

• CRISPR_ID: NC_015966_6
• CRISPR_location: 1987988-1988814
• CRISPR_type: Orphan
• Repeat_type: I-A,II-B,III-A
• Spacer_info: 12 spacers

Consensus repeat of NC_015966_6

Consensus_repeat	Method
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CRISPRCasFinder
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CRT
GTTTTAATCGCACCTTTTTGGTATTGAAAT	PILER-CR

spacers of NC_015966_6

>6.1|1988018|29|NC_015966|CRISPRCasFinder,CRT
AAAATATGATGGCCTTCATGGCGCCTCAA
>6.2|1988077|37|NC_015966|CRISPRCasFinder,CRT
GGACGCCTCCCACTCGGGTTCGAGCGCCTTGCGCGTG
>6.3|1988144|38|NC_015966|CRISPRCasFinder,CRT
GCAACAACAACAAACAATGGAGGTTGTCATGCACGCAA
>6.4|1988212|36|NC_015966|CRISPRCasFinder,CRT
GTTTACGCTACGGGAACGCATTCCGTCGTCCACAAG
>6.5|1988278|36|NC_015966|CRISPRCasFinder,CRT
CGACGTGCTCATGATCAAGCGACTCCATGAAGCAAG
>6.6|1988344|38|NC_015966|CRISPRCasFinder,CRT
CTGGCACATACACATCCCGGTGTTCGACACGCTTACGT
>6.7|1988412|38|NC_015966|CRISPRCasFinder,CRT
CTTGGACGGCAGGTCCTAGCTGGCTCAGACGTGCCGAG
>6.8|1988480|36|NC_015966|CRISPRCasFinder,CRT
AGTTTTTGTGAAAATGATGTGAAGTTTTAGTGAACA
>6.9|1988546|38|NC_015966|CRISPRCasFinder,CRT
CGGGTCTGCTACCCAGGCGATCTCGTCCGTGACGACAG
>6.10|1988614|36|NC_015966|CRISPRCasFinder,CRT
AACGAAACCGGCTTCGATGCCGTAGCCTTCACCTAC
>6.11|1988680|37|NC_015966|CRISPRCasFinder,CRT
TGTAAGCGTAACGACTCCCCGTCGCATCGTTGGCCAC
>6.12|1988747|38|NC_015966|CRISPRCasFinder,CRT
GCTGCGTGCCGCTTGGACGCCTGAAGCCATGCAGGATC
>6.13|1988078|37|NC_015966|PILER-CR
GGACGCCTCCCACTCGGGTTCGAGCGCCTTGCGCGTG
>6.14|1988145|38|NC_015966|PILER-CR
GCAACAACAACAAACAATGGAGGTTGTCATGCACGCAA
>6.15|1988213|36|NC_015966|PILER-CR
GTTTACGCTACGGGAACGCATTCCGTCGTCCACAAG
>6.16|1988279|36|NC_015966|PILER-CR
CGACGTGCTCATGATCAAGCGACTCCATGAAGCAAG
>6.17|1988345|38|NC_015966|PILER-CR
CTGGCACATACACATCCCGGTGTTCGACACGCTTACGT
>6.18|1988413|38|NC_015966|PILER-CR
CTTGGACGGCAGGTCCTAGCTGGCTCAGACGTGCCGAG
>6.19|1988481|36|NC_015966|PILER-CR
AGTTTTTGTGAAAATGATGTGAAGTTTTAGTGAACA
>6.20|1988547|38|NC_015966|PILER-CR
CGGGTCTGCTACCCAGGCGATCTCGTCCGTGACGACAG
>6.21|1988615|36|NC_015966|PILER-CR
AACGAAACCGGCTTCGATGCCGTAGCCTTCACCTAC
>6.22|1988681|37|NC_015966|PILER-CR
TGTAAGCGTAACGACTCCCCGTCGCATCGTTGGCCAC
>6.23|1988748|38|NC_015966|PILER-CR
GCTGCGTGCCGCTTGGACGCCTGAAGCCATGCAGGATC

CRISPR arrays and Neighbor proteins around NC_015966_6

CRISPR arrays

The CRISPR arrays of NC_015966_6

>merge|NC_015966|6|1987988-1988814|CRISPRCasFinder,CRT,PILER-CR
CTCTCAATACCAAAAAGGTGCGATTAAAACAAAATATGATGGCCTTCATGGCGCCTCAAGTTTCAATACCAAAAAGGTGCGATTAAAACGGACGCCTCCCACTCGGGTTCGAGCGCCTTGCGCGTGATTTCAATACCAAAAAGGTGCGATTAAAACGCAACAACAACAAACAATGGAGGTTGTCATGCACGCAAATTTCAATACCAAAAAGGTGCGATTAAAACGTTTACGCTACGGGAACGCATTCCGTCGTCCACAAGATTTCAATACCAAAAAGGTGCGATTAAAACCGACGTGCTCATGATCAAGCGACTCCATGAAGCAAGATTTCAATACCAAAAAGGTGCGATTAAAACCTGGCACATACACATCCCGGTGTTCGACACGCTTACGTATTTCAATACCAAAAAGGTGCGATTAAAACCTTGGACGGCAGGTCCTAGCTGGCTCAGACGTGCCGAGATTTCAATACCAAAAAGGTGCGATTAAAACAGTTTTTGTGAAAATGATGTGAAGTTTTAGTGAACAATTTCAATACCAAAAAGGTGCGATTAAAACCGGGTCTGCTACCCAGGCGATCTCGTCCGTGACGACAGATTTCAATACCAAAAAGGTGCGATTAAAACAACGAAACCGGCTTCGATGCCGTAGCCTTCACCTACATTTCAATACCAAAAAGGTGCGATTAAAACTGTAAGCGTAACGACTCCCCGTCGCATCGTTGGCCACATTTCAATACCAAAAAGGTGCGATTAAAACGCTGCGTGCCGCTTGGACGCCTGAAGCCATGCAGGATCATTTCAATACCAAAAAGGTGCGATTAAAAC

>NC_015966|6|6|1987988-1988814|CRISPRCasFinder
CTCTCAATACCAAAAAGGTGCGATTAAAAC	AAAATATGATGGCCTTCATGGCGCCTCAA
GTTTCAATACCAAAAAGGTGCGATTAAAAC	GGACGCCTCCCACTCGGGTTCGAGCGCCTTGCGCGTG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCAACAACAACAAACAATGGAGGTTGTCATGCACGCAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTTTACGCTACGGGAACGCATTCCGTCGTCCACAAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CGACGTGCTCATGATCAAGCGACTCCATGAAGCAAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CTGGCACATACACATCCCGGTGTTCGACACGCTTACGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CTTGGACGGCAGGTCCTAGCTGGCTCAGACGTGCCGAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGTTTTTGTGAAAATGATGTGAAGTTTTAGTGAACA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CGGGTCTGCTACCCAGGCGATCTCGTCCGTGACGACAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AACGAAACCGGCTTCGATGCCGTAGCCTTCACCTAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TGTAAGCGTAACGACTCCCCGTCGCATCGTTGGCCAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCTGCGTGCCGCTTGGACGCCTGAAGCCATGCAGGATC
ATTTCAATACCAAAAAGGTGCGATTAAAAC

>NC_015966|6|3|1987988-1988814|CRT
CTCTCAATACCAAAAAGGTGCGATTAAAAC	AAAATATGATGGCCTTCATGGCGCCTCAA
GTTTCAATACCAAAAAGGTGCGATTAAAAC	GGACGCCTCCCACTCGGGTTCGAGCGCCTTGCGCGTG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCAACAACAACAAACAATGGAGGTTGTCATGCACGCAA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GTTTACGCTACGGGAACGCATTCCGTCGTCCACAAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CGACGTGCTCATGATCAAGCGACTCCATGAAGCAAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CTGGCACATACACATCCCGGTGTTCGACACGCTTACGT
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CTTGGACGGCAGGTCCTAGCTGGCTCAGACGTGCCGAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AGTTTTTGTGAAAATGATGTGAAGTTTTAGTGAACA
ATTTCAATACCAAAAAGGTGCGATTAAAAC	CGGGTCTGCTACCCAGGCGATCTCGTCCGTGACGACAG
ATTTCAATACCAAAAAGGTGCGATTAAAAC	AACGAAACCGGCTTCGATGCCGTAGCCTTCACCTAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	TGTAAGCGTAACGACTCCCCGTCGCATCGTTGGCCAC
ATTTCAATACCAAAAAGGTGCGATTAAAAC	GCTGCGTGCCGCTTGGACGCCTGAAGCCATGCAGGATC
ATTTCAATACCAAAAAGGTGCGATTAAAAC

>NC_015966|6|3|1988048-1988814|PILER-CR
TTTCAATACCAAAAAGGTGCGATTAAAACG	GACGCCTCCCACTCGGGTTCGAGCGCCTTGCGCGTGA
TTTCAATACCAAAAAGGTGCGATTAAAACG	CAACAACAACAAACAATGGAGGTTGTCATGCACGCAAA
TTTCAATACCAAAAAGGTGCGATTAAAACG	TTTACGCTACGGGAACGCATTCCGTCGTCCACAAGA
TTTCAATACCAAAAAGGTGCGATTAAAACC	GACGTGCTCATGATCAAGCGACTCCATGAAGCAAGA
TTTCAATACCAAAAAGGTGCGATTAAAACC	TGGCACATACACATCCCGGTGTTCGACACGCTTACGTA
TTTCAATACCAAAAAGGTGCGATTAAAACC	TTGGACGGCAGGTCCTAGCTGGCTCAGACGTGCCGAGA
TTTCAATACCAAAAAGGTGCGATTAAAACA	GTTTTTGTGAAAATGATGTGAAGTTTTAGTGAACAA
TTTCAATACCAAAAAGGTGCGATTAAAACC	GGGTCTGCTACCCAGGCGATCTCGTCCGTGACGACAGA
TTTCAATACCAAAAAGGTGCGATTAAAACA	ACGAAACCGGCTTCGATGCCGTAGCCTTCACCTACA
TTTCAATACCAAAAAGGTGCGATTAAAACT	GTAAGCGTAACGACTCCCCGTCGCATCGTTGGCCACA
TTTCAATACCAAAAAGGTGCGATTAAAACG	CTGCGTGCCGCTTGGACGCCTGAAGCCATGCAGGATCA
TTTCAATACCAAAAAGGTGCGATTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_014067299.1|1995366_1996461_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223912
NC_015966.1|WP_014067295.1|1990969_1991917_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_015966.1|WP_014067298.1|1994214_1995360_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|378925
NC_015966.1|WP_014067289.1|1981331_1982258_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|132561
NC_015966.1|WP_014067292.1|1986235_1987903_+|hypothetical-protein	unknown	unknown	gnl|CDD|215425
NC_015966.1|WP_014067285.1|1977605_1977908_-|nucleotidyltransferase	unknown	unknown	gnl|CDD|224583
NC_015966.1|WP_014067286.1|1978139_1979060_-|DUF4340-domain-containing-protein	unknown	unknown	gnl|CDD|379518
NC_015966.1|WP_014067290.1|1984073_1984490_-|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NC_015966.1|WP_014067288.1|1980610_1981318_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|132557
NC_015966.1|WP_014067300.1|1996475_1997285_-|hypothetical-protein	unknown	unknown	gnl|CDD|143581
NC_015966.1|WP_014067294.1|1990003_1990966_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|235136
NC_015966.1|WP_014067296.1|1991937_1993272_+|TolC-family-protein	unknown	unknown	gnl|CDD|224455
NC_015966.1|WP_014067302.1|2000316_2001693_-|phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|100096
NC_015966.1|WP_014067287.1|1979080_1980607_-|gliding-motility-ABC-transporter-auxiliary	unknown	unknown	gnl|CDD|274627
NC_015966.1|WP_014067297.1|1993268_1994207_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_015966.1|WP_014067293.1|1989334_1989991_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|366102
NC_015966.1|WP_014067301.1|1997426_2000216_-|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|223972
NC_015966.1|WP_081472078.1|1983014_1983941_+|hypothetical-protein	unknown	unknown	gnl|CDD|335962
NC_015966.1|WP_014067291.1|1984766_1986101_-|glycoside-hydrolase	unknown	unknown	gnl|CDD|366513
NC_015966.1|WP_012844268.1|1984486_1984741_-|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|377269

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_014067299.1|1995366_1996461_+|ABC-transporter-permease	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	2.61585e-31
NC_015966.1|WP_014067295.1|1990969_1991917_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.49316e-89
NC_015966.1|WP_014067298.1|1994214_1995360_+|ABC-transporter-permease	gnl|CDD|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	6.43219e-36
NC_015966.1|WP_014067289.1|1981331_1982258_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|132561	TIGR03522, GldA_ABC_ATP, gliding motility-associated ABC transporter ATP-binding subunit GldA. Members of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldA is an ABC transporter ATP-binding protein (pfam00005) linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldA abolish the gliding phenotype. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.	1.88772e-128
NC_015966.1|WP_014067292.1|1986235_1987903_+|hypothetical-protein	gnl|CDD|215425	PLN02791, PLN02791, Nudix hydrolase homolog.	2.84018e-129
NC_015966.1|WP_014067285.1|1977605_1977908_-|nucleotidyltransferase	gnl|CDD|224583	COG1669, COG1669, Predicted nucleotidyltransferases [General function prediction only].	5.21127e-28
NC_015966.1|WP_014067286.1|1978139_1979060_-|DUF4340-domain-containing-protein	gnl|CDD|379518	pfam14238, DUF4340, Domain of unknown function (DUF4340). This domain is found in bacteria, and is typically between 183 and 196 amino acids in length.	5.64034e-26
NC_015966.1|WP_014067290.1|1984073_1984490_-|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	3.58019e-22
NC_015966.1|WP_014067288.1|1980610_1981318_-|ABC-transporter-permease-subunit	gnl|CDD|132557	TIGR03518, ABC_transporter_permease_protein, gliding motility-associated ABC transporter permease protein GldF. Members of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldF is believed to be a ABC transporter permease protein (along with ATP-binding subunit, GldA and a sunstrate-binding subunit, GldG) and is linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldF abolish the gliding phenotype. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.	2.62197e-55
NC_015966.1|WP_014067300.1|1996475_1997285_-|hypothetical-protein	gnl|CDD|143581	cd07177, terB_like, tellurium resistance terB-like protein. This family consists of tellurium resistance terB proteins, N-terminal domain of heat shock DnaJ-like proteins, N-terminal domain of Mo-dependent nitrogenase-like proteins, C-terminal domain of ABC transporter ATP-binding proteins, C-terminal domain of serine/threonine protein kinase, and many hypothetical bacterial proteins. The function of this family is unknown.	3.64184e-06
NC_015966.1|WP_014067294.1|1990003_1990966_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	2.35335e-61
NC_015966.1|WP_014067296.1|1991937_1993272_+|TolC-family-protein	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	9.09814e-50
NC_015966.1|WP_014067302.1|2000316_2001693_-|phosphoglucosamine-mutase	gnl|CDD|100096	cd05803, PGM_like4, This PGM-like (phosphoglucomutase-like) domain is located C-terminal to a mannose-1-phosphate guanyltransferase domain in a protein of unknown function that is found in both prokaryotes and eukaryotes. This domain belongs to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this superfamily include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NC_015966.1|WP_014067287.1|1979080_1980607_-|gliding-motility-ABC-transporter-auxiliary	gnl|CDD|274627	TIGR03521, gliding_motility_protein_GldG, gliding-associated putative ABC transporter substrate-binding component GldG. Members of this protein family are exclusive to the Bacteroidetes phylum (previously Cytophaga-Flavobacteria-Bacteroides). GldG is a protein linked to a type of rapid surface gliding motility found in certain Bacteroidetes, such as Flavobacterium johnsoniae and Cytophaga hutchinsonii. Knockouts of GldG abolish the gliding phenotype. GldG, along with GldA and GldF are believed to compose an ABC transporter and are observed as an operon. Gliding motility appears closely linked to chitin utilization in the model species Flavobacterium johnsoniae. Bacteroidetes with members of this protein family appear to have all of the genes associated with gliding motility.	1.94506e-90
NC_015966.1|WP_014067297.1|1993268_1994207_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.97757e-103
NC_015966.1|WP_014067293.1|1989334_1989991_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	5.0517e-13
NC_015966.1|WP_014067301.1|1997426_2000216_-|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	gnl|CDD|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	0
NC_015966.1|WP_081472078.1|1983014_1983941_+|hypothetical-protein	gnl|CDD|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	5.99475e-35
NC_015966.1|WP_014067291.1|1984766_1986101_-|glycoside-hydrolase	gnl|CDD|366513	pfam01204, Trehalase, Trehalase. Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.	2.36858e-20
NC_015966.1|WP_012844268.1|1984486_1984741_-|DUF433-domain-containing-protein	gnl|CDD|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	4.53993e-24

Protein sequences

>NC_015966.1|WP_014067292.1|1986235_1987903_+|hypothetical-protein
MRRYLLLFALLLLPACETPETMPEASLDTVLTVPGASPEAQALLRKYAPFRLEADLSGLSDNQRRILGLLIEAAREMDAIFKVQAYGNLDSLLATIEDPGLRRFVEINYGPWDRLDGNRPFLEGVGPKPPGANFYPPDMTREEFEVAAAENEALRSLYTMVRRDAQGRLVAIPYHEFFAPHVRRAAELLRQAAELAEDEGLRRYLTLRAEALLTDDYYESDRAWLDMKTNTIDVVIGPIETYEDQLFGYKAAAEAFVLLKDRAWSERLGRYATLLPELQAALPVPDAYKREQPGTDSDLGAYDALYYAGDANAGAKTIAINLPNDERVQLEKGTRRLQLKNVMRAKFEKILLPIADVLIAEDQRTHITFDAFFGNTMFHEVAHGLGIKHTIAGRGTVREALRDLYTTMEEGKADVLGLYMVTWLIDRGEWEADPMDHYVTFLAGIFRSIRFGAASAHGRANLIRFNFFKEQGAFTRDAATGTYRVVPERMQAAVAALSEQILRLQGDGDYAATAAFIERYGQMDDTLRADLARIQQAGIPVDIVFIQGPEVLGLE
>NC_015966.1|WP_014067291.1|1984766_1986101_-|glycoside-hydrolase
MSEPIVIDPEALIEQARAVLRANDVNGIFIKPGTYQYPHQWNWDAALVALGLSHFDRPRAEQEIRSLLKGQWKDGMLPHVVYHNGASDYFPTPDFWQIERSPNAPEGVLTSGIVQPPLLATCVRLMHERAPDREASLAFVREIYPALYRWHRWLHTARDPENTGLVAIVHPWESGTDNAARFVEPMIRVIPTRVPAYQRKDFLHVREDERPIQAEYQRFIYLIDLFRQWGYDQETIYARSPFLVQDTLFNALMYRAQRDLRALAAELGEPTEEFDEWLATTRYAYNARLWSEEHGLYFAYDLRARRVLEENGCATFIPLFAGLASERQARRLVEEHLLNPEEYAPDGTRYYVPSQAKNNLFFEPRRYWRGPVWIIINWMVMEGLRRYGYHELAETIRQHSLELVQKSGFMEYYDPRDGTGCGATGFSWTAALTIEMLAGQPVPA
>NC_015966.1|WP_012844268.1|1984486_1984741_-|DUF433-domain-containing-protein
MKARFPVPGLERITFDPEVMGGRACIRDTRVTVSLILNLLANGMQVHEILEAYPYLEPEDIHQALKYAAWLSEEWVVPLSPETP
>NC_015966.1|WP_014067290.1|1984073_1984490_-|hypothetical-protein
MRFLADMGISPHTVRFLREQGYDAVHLRELKGQLLTDASILELARTERRILLTHDLDFGELMAASGARLPTVIVFRLRNMRPENVNRYLMGIIDRFGDQLRAGAMVSVTEAQVRIRSLPLSSYMGSLIFRCMMAPCQR
>NC_015966.1|WP_081472078.1|1983014_1983941_+|hypothetical-protein
MEAPTSWRLYEAFVEHVTATGRLSVLAGLYDLNSEFDVLPAAGLFINSSFGIGAELAASRPQGPSIFPVTSPGLRVRLGFQRSARYAGYLQAVALDGVPGDPDRPAGTHIVFGRNDGLLLVAEAGALVHPEAPLPDGSPIQLVSRLHEHPHHHKLALGLWYYTARFRWLDADRTQRGNAGVYLLAESRLYREDPRTLWAFLRVGLAHPRVNRFGAYTGGGLSGRGWVPGRPADRMGLAVAAAHNSSAYRHLQRQQGTPVHRTEWVFEGTYLLALSTALRLQFDLQWVLHPDTRAGSVLVGGLRLLWSP
>NC_015966.1|WP_014067289.1|1981331_1982258_-|ATP-binding-cassette-domain-containing-protein
MIEVRELTKRYGSEVAVDRISFTVRSGEVLGFLGPNGAGKTTTMKVITCYLPPTEGTVLVDGLDVRHDSLAIRQKIGYLPENTPLYPDMVTYDYLEFMAAMRGLDGAARRRRLAEVIEVCGLGDVLTKRIDALSKGYRQRVGLAQAMVHDPPILILDEPTSGLDPNQIVEIRSLIKTLGREKTVILSTHILPEVQASCDRVLIIHRGRIVADGTPDELQTAHGGQRILFGVQAPEPEVRSALERMDGVRVEEARTESDGTLLLRLSADGQRDLRPELFRLAVERGWTLTELHRERVDLEEVFRQLTMN
>NC_015966.1|WP_014067288.1|1980610_1981318_-|ABC-transporter-permease-subunit
MREVWILTRRELRAFFDSPSAYIVLSVFLLITGWFFGNSLFVENVASLRSVFDLAPVLFMFFIPALTMGTFAEERRAGTIELLLTLPVRDGQVIAAKLLSVVIVLVVALALTGVYVLTLAVLGDPDNGGTLGGYLGLALLGLSCSALGLLASSLTRNQIVAFILGFAMIFGLYLLDKVTIFAPGWLAPILEYLSIDFHYRNLMRGVIDSRDVLYYLSLTAFAGLLTAYHLARRPE
>NC_015966.1|WP_014067287.1|1979080_1980607_-|gliding-motility-ABC-transporter-auxiliary
MQRNWTTRTTLLLVGLILVVLNLIGLNVFFRIDLTDDRVYSLSEASIETVRSLEDPVTVRVFFTADLPAPYSSYRRFLRDKLDEYRAYGGNKFQYEFLDPGSDESLQQEAARYNIPPVQVQVIENDNLQIKNAYMGLVVEYAGKRETIPVIEDLSTLEYDLTSAIRKLTRDRLPVAGILTGHGEPGRTAIETFWRALERNYEVRTVSVKDSTLDPRPDVLFIIAPTDTFPEAHLKAIDRYLMEGGRVAVLLNRINANLQFGFASEQKTGLEDLLAHYGAVVRPDLVMDRQSSVVTLQRTVGFFRVAQMVEYPFFPIATRFNLEHPMVSRLREVFFYYVSSIDTSAALPEGVERIPLVYSTPRSATQQGFFTVQPAMLPDPENFRDGPYVLAVALHGTFPSAYDSTRVGQPARLVVVGDGDLVNEQRYGGQLPPGNLAFVLNIADWLGQDEALLAIRTKSIAPRALEPVSESLRPFIKYANILGPVVLVVLFGLIRWRIRRQRQIVLTT
>NC_015966.1|WP_014067286.1|1978139_1979060_-|DUF4340-domain-containing-protein
MSRKNPVVILSIVLVVLLVLAWATGAFKRNPSTIDVPEWTLRADEITRIQLERPGKDPLVLERSGSGWQLTAPIRYPADSSFARRFVENLAETELESVVSTNPARYGNYGVADSNAIRLVVYRKAGDSLQLFWGNTGPDFNARYVRLATDERVFLARTDLTFPEDLSRWRDKTILNVPAGQLEALEVQHEGKRYGVRRGESGWELVEDDQTAPADSAAAARWAGQFDPLRADGFFDDLPADSIRRAPDYVLTLRLPGGVQQVLYFDERSNGWALVRGDDETVFRIYAYRRNQLLPEASSLRAKSEE
>NC_015966.1|WP_014067285.1|1977605_1977908_-|nucleotidyltransferase
MKTEQRLLQRLREKREEILRLCARYGATDVRVFGSVARGEADVASDVDLIVRFEPGRSLLDHAALWLELEALLGCRVDVISESGLKPRIREKVLKEAIPL
>NC_015966.1|WP_014067293.1|1989334_1989991_+|TetR/AcrR-family-transcriptional-regulator
MVSSETTPAAVRARILEAARRRFFQEGYARVTMDELARELGMSKKTLYQHFPTKAALAAAVMEAFRSQVAESLGRIFEDLTLSLPERLARAFAEAAHHLRQIEKPFLEDLARFLPDVWAETERFRSETIARLLGGALREGQAAGFIRTDVPVEILLRSFQAVAECLVTPAALMELPYTLPEMIRLVIQLLFEGMLTDTARGDFRKALDAIASGENLTT
>NC_015966.1|WP_014067294.1|1990003_1990966_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MRTLLIPVLLGGLLAGCRAARTDVLEVSGTIEATEIQLAARTTGEIVRFFVDEGDRVARGQPLVCQDTTQLALQLRQAEADVAAARANLALLEAGARAEDLEQAEARRQQAETRLEQARRDAARLEALHAQGSATDRQLEDARLQLRLAEAEYRAAQAQLEKLRHLARPEELAVARARVAQAEARRDLLRRQLEDACLEAPTDGVVSRRVADPGELAAPGSVLLTLVQLDTVYVQLYIPEPLIGAIRYGQPVTVRVDTWPDRTFEGHVTYIAPEAEFTPRNVQTKEDRTRLVFRIKVALPNPEGLLKPGMPADATLQPAA
>NC_015966.1|WP_014067295.1|1990969_1991917_+|ABC-transporter-ATP-binding-protein
MTPPIELRAATKRFGPITALAGVSLSVSEGEMFGLVGPDGAGKTTLLRLVAGIARADEGVVRVLGHDLTTKARRIRPFIGYMAQRFSLYGDLTVEENLRFFARLHGTGTDRAWQERLLEMTGLAPFRNRLADYLSGGMKQKLALICTLVYRPRLLLLDEPTTGVDPVARRQFWELLVEFQQEGLTIVLATPYLDEAERCRRVALLHQGRILALDTPEALRASLPGRLFELTATPVREAARRLRTWLAAHRVQLIGNRIHLLLDRDDELTPLLGRLEADGSVQVHDCQPIAPTLENVFLAYLTEQSTPSKQIADVR
>NC_015966.1|WP_014067296.1|1991937_1993272_+|TolC-family-protein
MLRWLPGLLLGFGLALALQAQPVQLTLSEAIQQGLRTHPDLAAAEAAVAAAQARIGQARAALQPRLQFSAGYQRLSEITPFAITMPLPGAEPIEITPNIPNQYQLQLSLQQPLFQGGRLRAQLEAARQEAAAAVAEQHARREALAYRIATAYWQHVEAEALARAAEENVRRLEAHLQDARNRQAQGLLLESEVLDVEVALEQARLEALRQRQAARLTAVTLSSLVGLPPDTPLVLSDRPDTAAQPVPSLDSLRALALRRRPDLAALRHTIARADALRAMARAGWWPQVALVGRYLYARPNPRLIPLQDRFEGTWEVGLSLTLDLWNGLRTHHQVAETTALRRQAEAQKAATLRTLDVTLAQARLGVEQAYERLRLARLVVRQAEARYALVRDQFAQGLRTSRDLLDAETTLAQARAREIQARTACALAWLALYQATGTLTEHLP
>NC_015966.1|WP_014067297.1|1993268_1994207_+|ABC-transporter-ATP-binding-protein
MSTPAIDVRDLTRRFGSFTAVDHVTFQVEAGEIFGFLGANGAGKSTTIRMLCGLLPPSGGTARVAGFDVAREPYRVRQAIGYMAQKFSLYEDLTGLENLYFFGTAYGLTGRRLETRIREVTVRVGLSGQERRLVRELPTGWRQRLALASALLHEPSVVFLDEPTSGVDPLARRRFWDLIAELAAEGTTVFVTTHYLDEAEYCNRLGLIQGGRLIALGAPEALKARYLIRPLYELEAIPLRAALEALRRMPEVFEADPFGSRIHVTLQDRSLDPELLVRRLREAGLTVAGIRPIVPTLEDVFLHLIEHPPTET
>NC_015966.1|WP_014067298.1|1994214_1995360_+|ABC-transporter-permease
MAALRMIATLFVKEFTQIRRDPLSLGMLIALPAFLLVLFGYALTFDVRNLSLGVCDQDGSAASRELIRRFAITEYFDLKRQVDDPRALTRLIDHEVIRVGLVIPPDFEERLEAGRPAPVQFLVDGTNATIASAVTGYADAIVRAFSGQVVLEQMLRAGHRPPPAAVSVEARIWYNPELESARFLLPGLIAFLLMVATVVATSLSVTRERERGTMEQLVLAPLEPYQLVLGKTLPYLLVAIGSTVLILLVGRLLFDVEVRGDLLVLAFVVLAYLLAGLGQGLLISTVAPSQQVAFQIAIISTLLPTFILSGFVFPIYNMPPIIQALTYLVPARYFLVALRGVMLKGTGLAVFWPDVLLLLLFAGLMLTLSSVRLRRLFQHLM
>NC_015966.1|WP_014067299.1|1995366_1996461_+|ABC-transporter-permease
MEQVLAFLRKEFRQLRRDPRMLFLLIVPPIVQLVLLGYAANLDVRHVPLVVCDPVPSATSRDLVQRLVASTYFDLVGYEPDARRVGEWLDRGEATVALVFPPDFGKEVAQGTTASVQLLVDGSETNTATVALSYASQIIQHALGVGAVSAGVVPELRVWFNPALSSRWFIIPGLVGLLLTVMTTVLTALALVKEKETGTLEQLLVTPLRPATVLLGKLVPFLLIGLLDVLLVVLVATLWFQVPLRGSIPLLFGCALLFLLNTLGLGLLISTLSRTQQQALIGAAFFALMPMIILSGFVFPIESMPPVIRAVTHIVPLRYFLTIVRGIFLKGVGMPALWEEMLALLVLGLLLFGLSTWRFRRQLH
>NC_015966.1|WP_014067300.1|1996475_1997285_-|hypothetical-protein
MSETRCMAGRLQELALLYLIAASREGLPVGDGRLEAVIDQLQARCPTIPPDQLRALVLEAFDVLLAAEDPEALLQATLEAVEPHLSQAQRQAVLHDLLRIAEADGIVMESERQLLELVARRWGLEPPYERVRVLDPGQEGIPEVLIHLALLYLVLAHGVDHELTRQERQIIVRKLRAWCPDLTDQQLAAVLQEAIDRYAEGLTDAELRASAEAIKMALTPAQRLTAFHDLVQIANADGTFLDTEEDLLNELVDLWELGPHVDAPELSPA
>NC_015966.1|WP_014067301.1|1997426_2000216_-|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase
MEARPDVMQHDPSHELFLPRRLHLDAIFRPRSVAVIGASERPGSVGRTLLWNLISNPFGGTVYPVNPKRTNVLGIRAYPSVKDIPEPVDLAVIATPAPTVPGVVQECVEAGVKGAVIISAGFKEIGEEGRRLEEQILTIARKGGMRIIGPNCLGVMRPVTGLNATFASTMARPGTVGFISQSGALLTSILDWSLEENVGFSAFISIGSMLDVGWGDLIYYLGSDPYTKSIILYMESIGDARSFLSAAREVALQKPIIVIKAGRTEEAARAALSHTGSLAGSDEVLSAAFRRTGVLRVDSIADLFYMAEVLAKQPRPEGPRLTILTNAGGAGVLATDALVQGGGQLAELSEETKKKLDEFLPPHWSHGNPVDILGDADPERYAKALEVTLADENSDGLLVILTPQAMTDPTQTAEQLRRFAQSRKPILASWMGGVEVAAGKKILNRAGIPTFQYPDTAVRVFNYMWRYSYNLRALYETPSLPDDEIDGGPDRERAQQIIEQVRREGRTLLTEYEAKQVLEAYCLPVTPTRLARTADEAVAAAEELGYPVVLKLHSLKITHKTDVGGVQLNLDSPEAVRRAFETIRRNLEERGQADAFDGVTVQPMVRARDGYELIIGSTIDPQFGPVLLFGAGGTLVEVYRDRALGLPPLNTTLARRMMEQTKVYRALQGVRGRPPVNLDRLEKLMVRFSQLVVEQPWIREIDVNPLLAAPDQIVALDARIVLHPPDLREEELPRPAIRPYPRQYMGTWRLKDGTPVLIRPIRPEDEPLLVEFHHKLSERSVYLRYASLLKLSQRVAHERLARLCFIDYDREMALVAERRSPETGRPEILAVARLTKIYGTNDGEFAMLVRDDVQGKGLGTELLRRLIQIGEAEGLERIVADILVQNHAMQHVCRKLGFRIIRSDDPADPMVKAVRVLRVPVERESLAKA
>NC_015966.1|WP_014067302.1|2000316_2001693_-|phosphoglucosamine-mutase
MAEKQVLIASISGIRGIFGAGLGPEELVRYAAAYGAWLRKQIGGRRPRVVVGRDGRVTGPVCARIVTATLQSVGCDVLDAGLATTPTVEVAVTAAQADGGIVLSASHNPAEWNALKLLNRHGEFLTPDEAREVLTLAEAGAMPLVTWEALGTYEARDFLDAHIQRILALDFMDPERIRQRQFRVVVDGINSVGAVALPVLLRRLGVAEVLLLNGEPNGRFAHPPEPLPEHLQETIRAVADTGADLGLVVDPDADRLALIADGGEYVSEELTQVIAADFLWRFREGPFVTNLSSSRAIEDVAARYGMPVYRAAVGEINVVQKMKEVGAILGGEGNGGVILPDVHYGRDALVGAAMVLQHLANLEQSLSELVASLPRYAIVKHKLPLDNLDADQALQRLAGRYAHARITTIDGLKIDLDEGWVHLRKSNTEPILRIYAEAQTPDEAAALVQRFVDELRSV

Crispr_ID: NC_015966_7

• CRISPR_ID: NC_015966_7
• CRISPR_location: 2031620-2031764
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_015966_7

Consensus_repeat	Method
TGGAGGTGCTGCTGGCCGAGACAGAAAAACGACTGGATCATCGAAT	CRISPRCasFinder

spacers of NC_015966_7

>7.1|2031666|53|NC_015966|CRISPRCasFinder
CACCGAAGAAATAGCCCGTCTGGACAAACGAATTGCAGAGGAAGTGACGCGTC

CRISPR arrays and Neighbor proteins around NC_015966_7

CRISPR arrays

The CRISPR arrays of NC_015966_7

>merge|NC_015966|7|2031620-2031764|CRISPRCasFinder
TGGAGGTGCTGCTGGCCGAGACAGAAAAACGACTGGATCATCGAATCACCGAAGAAATAGCCCGTCTGGACAAACGAATTGCAGAGGAAGTGACGCGTCTGGAGGTGCTGCTGGCCGAGACAGAAAAGCGACTGGATCATCGAAT

>NC_015966|7|7|2031620-2031764|CRISPRCasFinder
TGGAGGTGCTGCTGGCCGAGACAGAAAAACGACTGGATCATCGAAT	CACCGAAGAAATAGCCCGTCTGGACAAACGAATTGCAGAGGAAGTGACGCGTC
TGGAGGTGCTGCTGGCCGAGACAGAAAAGCGACTGGATCATCGAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_014067333.1|2032338_2033769_-|sodium:proton-antiporter	unknown	unknown	gnl|CDD|224671
NC_015966.1|WP_014067336.1|2035411_2035732_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_015966.1|WP_014067328.1|2029101_2029485_-|twin-arginine-translocation-signal-domain-containing-protein	unknown	unknown	gnl|CDD|376534
NC_015966.1|WP_014067332.1|2032082_2032289_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014067339.1|2037347_2039018_+|S41-family-peptidase	unknown	unknown	gnl|CDD|223864
NC_015966.1|WP_014067322.1|2021319_2022069_+|2-phosphosulfolactate-phosphatase	unknown	unknown	gnl|CDD|377205
NC_015966.1|WP_014067325.1|2025082_2025997_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NC_015966.1|WP_014067323.1|2022122_2024594_+|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|224588
NC_015966.1|WP_014067334.1|2033781_2034372_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|239267
NC_015966.1|WP_012844319.1|2039718_2040417_-|phosphate-signaling-complex-protein-PhoU	unknown	unknown	gnl|CDD|273990
NC_015966.1|WP_014067340.1|2039187_2039628_+|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl|CDD|107221
NC_015966.1|WP_014067326.1|2026035_2026827_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|223377
NC_015966.1|WP_014067321.1|2020102_2021230_+|glycine-cleavage-system-aminomethyltransferase-GcvT	unknown	unknown	gnl|CDD|234742
NC_015966.1|WP_014067329.1|2029577_2029871_-|acylphosphatase	unknown	unknown	gnl|CDD|224174
NC_015966.1|WP_014067324.1|2024610_2025078_-|type-I-restriction-enzyme-HsdR-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|372640
NC_015966.1|WP_014067338.1|2036562_2037165_-|LemA-family-protein	unknown	unknown	gnl|CDD|377192
NC_015966.1|WP_014067337.1|2035746_2036559_-|TPM-domain-containing-protein	unknown	unknown	gnl|CDD|224429
NC_015966.1|WP_014067327.1|2026953_2029032_+|alpha-glucan-family-phosphorylase	unknown	unknown	gnl|CDD|273968
NC_015966.1|WP_014067330.1|2029867_2031247_-|alpha-amylase	unknown	unknown	gnl|CDD|200452
NC_015966.1|WP_029698451.1|2034445_2035297_-|zinc-metalloprotease-HtpX	unknown	unknown	gnl|CDD|320695

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_014067333.1|2032338_2033769_-|sodium:proton-antiporter	gnl|CDD|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	5.11616e-50
NC_015966.1|WP_014067336.1|2035411_2035732_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.1298e-09
NC_015966.1|WP_014067328.1|2029101_2029485_-|twin-arginine-translocation-signal-domain-containing-protein	gnl|CDD|376534	pfam01355, HIPIP, High potential iron-sulfur protein.	0.00614999
NC_015966.1|WP_014067339.1|2037347_2039018_+|S41-family-peptidase	gnl|CDD|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	3.93369e-103
NC_015966.1|WP_014067322.1|2021319_2022069_+|2-phosphosulfolactate-phosphatase	gnl|CDD|377205	pfam04029, 2-ph_phosp, 2-phosphosulpholactate phosphatase. Thought to catalyze 2-phosphosulpholactate = sulpholactate + phosphate. Probable magnesium cofactor. Involved in the second step of coenzyme M biosynthesis. Inhibited by vanadate in Methanococcus jannaschii. Also known as the ComB family.	8.32823e-99
NC_015966.1|WP_014067325.1|2025082_2025997_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	2.32255e-120
NC_015966.1|WP_014067323.1|2022122_2024594_+|DNA-translocase-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	3.47208e-136
NC_015966.1|WP_014067334.1|2033781_2034372_-|thioredoxin-family-protein	gnl|CDD|239267	cd02969, PRX_like1, Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic cysteine found in PRXs, which aligns to the second cysteine in the CXXC motif of TRX. In addition, these proteins do not contain the other two conserved residues of the catalytic triad of PRX. PRXs confer a protective antioxidant role in cells through their peroxidase activity in which hydrogen peroxide, peroxynitrate, and organic hydroperoxides are reduced and detoxified using reducing equivalents derived from either thioredoxin, glutathione, trypanothione and AhpF.	6.80357e-89
NC_015966.1|WP_012844319.1|2039718_2040417_-|phosphate-signaling-complex-protein-PhoU	gnl|CDD|273990	TIGR02135, Uncharacterized_protein, phosphate transport system regulatory protein PhoU. This model describes PhoU, a regulatory protein of unknown mechanism for high-affinity phosphate ABC transporter systems. The protein consists of two copies of the domain described by pfam01895. Deletion of PhoU activates constitutive expression of the phosphate ABC transporter and allows phosphate transport, but causes a growth defect and so likely has some second function. [Regulatory functions, Other, Transport and binding proteins, Anions].	6.13376e-54
NC_015966.1|WP_014067340.1|2039187_2039628_+|Hsp20/alpha-crystallin-family-protein	gnl|CDD|107221	cd06464, ACD_sHsps-like, Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally active as large oligomers consisting of multiple subunits, and are believed to be ATP-independent chaperones that prevent aggregation and are important in refolding in combination with other Hsps.	1.63573e-35
NC_015966.1|WP_014067326.1|2026035_2026827_+|SDR-family-oxidoreductase	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	8.27519e-91
NC_015966.1|WP_014067321.1|2020102_2021230_+|glycine-cleavage-system-aminomethyltransferase-GcvT	gnl|CDD|234742	PRK00389, gcvT, glycine cleavage system aminomethyltransferase GcvT.	0
NC_015966.1|WP_014067329.1|2029577_2029871_-|acylphosphatase	gnl|CDD|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	1.19114e-36
NC_015966.1|WP_014067324.1|2024610_2025078_-|type-I-restriction-enzyme-HsdR-N-terminal-domain-containing-protein	gnl|CDD|372640	pfam13588, HSDR_N_2, Type I restriction enzyme R protein N-terminus (HSDR_N). This family consists of a number of N terminal regions found in type I restriction enzyme R (HSDR) proteins. Restriction and modification (R/M) systems are found in a wide variety of prokaryotes and are thought to protect the host bacterium from the uptake of foreign DNA. Type I restriction and modification systems are encoded by three genes: hsdR, hsdM, and hsdS. The three polypeptides, HsdR, HsdM, and HsdS, often assemble to give an enzyme (R2M2S1) that modifies hemimethylated DNA and restricts unmethylated DNA.	3.05007e-42
NC_015966.1|WP_014067338.1|2036562_2037165_-|LemA-family-protein	gnl|CDD|377192	pfam04011, LemA, LemA family. The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.	2.1456e-73
NC_015966.1|WP_014067337.1|2035746_2036559_-|TPM-domain-containing-protein	gnl|CDD|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	3.90459e-65
NC_015966.1|WP_014067327.1|2026953_2029032_+|alpha-glucan-family-phosphorylase	gnl|CDD|273968	TIGR02094, Glycogen_phosphorylase, alpha-glucan phosphorylases. This family consists of known phosphorylases, and homologs believed to share the function of using inorganic phosphate to cleave an alpha 1,4 linkage between the terminal glucose residue and the rest of the polymer (maltodextrin, glycogen, etc.). The name of the glucose storage polymer substrate, and therefore the name of this enzyme, depends on the chain lengths and branching patterns. A number of the members of this family have been shown to operate on small maltodextrins, as may be obtained by utilization of exogenous sources. This family represents a distinct clade from the related family modeled by TIGR02093/pfam00343.	0
NC_015966.1|WP_014067330.1|2029867_2031247_-|alpha-amylase	gnl|CDD|200452	cd11313, AmyAc_arch_bac_AmyA, Alpha amylase catalytic domain found in archaeal and bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes firmicutes, bacteroidetes, and proteobacteria. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	5.53423e-170
NC_015966.1|WP_029698451.1|2034445_2035297_-|zinc-metalloprotease-HtpX	gnl|CDD|320695	cd07336, M48B_HtpX_like, Peptidase M48 subfamily B HtpX-like membrane-bound metallopeptidase. This HtpX family of peptidase M48 subfamily B includes uncharacterized HtpX homologs and consists of proteins smaller than Ste24p, with homology restricted to the C-terminal half of Ste24p. HtpX expression is controlled by the Cpx stress response system, which senses abnormal membrane proteins. HtpX participates in the proteolytic quality control of these misfolded proteins by undergoing self-degradation and collaborating with FtsH, a membrane-bound and ATP-dependent protease, to eliminate them. HtpX, a zinc metalloprotease with an active site motif HEXXH, has an FtsH-like topology, and is capable of introducing endoproteolytic cleavages into SecY (also an FtsH substrate). However, HtpX does not have an ATPase activity and will only act against cytoplasmic regions of a target membrane protein. Thus, HtpX and FtsH have overlapping and/or complementary functions, which are especially important at high temperature; in E. coli and Xylella fastidiosa, HtpX is heat-inducible, while in Streptococcus gordonii it is not.	1.76408e-164

Protein sequences

>NC_015966.1|WP_014067330.1|2029867_2031247_-|alpha-amylase
MRPLFYLWLILLIATGCEAPPEQELPRVPPGVGQPDWIADAVLYEIFVPDFSPEGTFQGVIRRLDSLQALGVNTLWLMPIHPVGKKRAKTDIGPLGSPYAVRDYYAVNPDYGTEEDFRALVDSVHARGMHIIIDLVANHTAWDNPWVTEHPDWYTPGPIDGFTYPVLNGDTTDWTDVVDLNYDNPELRQAMIDVMQYWVREFDIDGYRCDVAHGVPLDFWKAAIDSVEKIKPVLMLAEAAEPEMHLVGFDLTYAWPFYHQLKEVWRGAPLHTLVRQVDSTLGLLPPGARRLRFTTNHDETMWDAPPPVLFGGDEGSMAAFVLATSMPGVPLLYNGQELGVRERVSFFARTPYNWEAPESPALYAFYRRYVNFYRASEALRHGELTVLNPEADDVLVYLRATEADTLLLIVNVRNRPETVALPEGIRGRRWVEVFGSDTLATDTLQLDPYNYRIYQPLRP
>NC_015966.1|WP_014067329.1|2029577_2029871_-|acylphosphatase
MSSLDAQARLEARVTGRVQGVGFRQFVRYHARRLGLTGWVRNEPDGSVYLVAEGPRELLEQLLDVVRQGPPAARVDDMQVHWLPARGEFEAFEIRWW
>NC_015966.1|WP_014067328.1|2029101_2029485_-|twin-arginine-translocation-signal-domain-containing-protein
MEDKRVTRRDFLLRVGALGLAGLGGSALLSACGGGQQQQQQSGAASESGTSASAELTCTDVSGLTAEEIQMRESLQYTDHSPYPDKTCANCQLFIPPENPNQCGACQLIKGPIHPNGYCTSWVQKAT
>NC_015966.1|WP_014067327.1|2026953_2029032_+|alpha-glucan-family-phosphorylase
MTTRDKLEALVANLWWSWNPEALQLFERLNPEAFRVSHHNPLAALRAADPAVLSDRPFQKEVDRVYEAFQAYLNSPPRIENAPRTVYFCMEYGLHESLPFYAGGLGVLAGDHIKAASDLGIPMTAVGLFLREGYFRQRFDHSGWQLADYPAMDPLDHPMSLVHGPDGYPLVITVHLGRQPLYLRAWKLEVGRVPLYLLDASFDANPEPLRILTRRLYQGDRRIRLQQEIILGIGGVRLLRALEQDFDVYHMNEGHCAFVALELLRERLAAGDEREAAEAWVRQHCVFTTHTPVMAGHDRFDPGLLLEQMESFRHQLGLSETDLLAYGRVNPSDSTEAFNMTVLGLKMSRKSNGVSAINGLVARRQWHHLYPDRPVNEVPIGHITNGVHLPTWTAPHARPFLEQHLGDWLEGRFNVEIWKKVDDISDAELWQYRCMLRRRLVEFVNEYVKHQSLPQESHLNPDVLTIGFARRFATYKRAPLLFEDMERAIQLFTREDRPIQMIYSGKAHPADDGGKRFIQQIYEITQHPAFRGKVVFVEDYDMHIARMLVSGCDVWLNNPRRPLEASGTSGQKTAMHGGLNLSVLDGWWPEAYNGQNGWAFGREATGYYEDPVTQDVEDREALYRVLEYEVIPAFYERNGEGLPIRWLTRMRQAMRTIPARFNAVRMVREYVEQIYRAAEAPAPVAATIKNEK
>NC_015966.1|WP_014067326.1|2026035_2026827_+|SDR-family-oxidoreductase
MKTFKNKTILITGASSGIGEAMVYQLRDPSVKLLLVARSGDKLQAMVEALERQGVWAQAYPCDLAQPGAAEALFQRLTEDGYRVDVLINNAGFGKYGRFDQISLSDTLEMLRLNIENLVALTHLCIPHMLERGDAGILNVASTAGFQGIPYMAVYAATKSFVISFSEALHAEYADRGITVTCLCPGPTATAFQERAGMPVEGVRRFMESAEKVAIAGLRALLRGEVVHVSGASNAVVARLSQLAPRRVRLAVTRQLLGPHDDT
>NC_015966.1|WP_014067325.1|2025082_2025997_-|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MLAIMTGIDPVENGTITQGELLQQAIQRLEAAGVPDARRNAEWMLCEVLGCSRAQLYAYPERPVDAVRRTRFAELLARRLRREPLQYVLGYVEFLGLRLEVGPGVLVPRPETEWLTERVLQELQSTPAPRVLDVGTGSGCIALAIKHHRPDADVWACDISPEALAIARRNAERLGLEVHWVEADVLTDAFPEKVPGPFDLIVSNPPYLALHEANELPPEVRDYEPPVALYAGEDPLRFYRALARHGHALLKPGGRLACEVHAHYGADVVALFEASGYEAVRLERDLAGNRRLVWARRPVSAPSF
>NC_015966.1|WP_014067324.1|2024610_2025078_-|type-I-restriction-enzyme-HsdR-N-terminal-domain-containing-protein
MEALNFPAYSFRLQRRGEQVYLLDPLRRRWVRLTPEEWVRQHLAQYLVQALKCPPSLVALEASFTDQGMGRRADLVVYDRAGRPLLLAECKAPTVPITQEVIEQAGRYNRVIGAPYLLVTNGHIHYLWHIDPTQRTMTPLPRWLTYAEMLERRWG
>NC_015966.1|WP_014067323.1|2022122_2024594_+|DNA-translocase-FtsK
MAGTTSRRRRKARKPEKEAAPAISPTRRREILGLTLMVLGVLLTLALVTYHPSDNGLARHFSLGAALDPGNNRAENALGLVGASLAYVLMARLFGYASVLLTGLLVAWGYVIFRGRRPRALPLFSGLILLLVPLLAASFGWIGVVFEADLHAWSGDLGLGLAGWMTRVFGTVGALGLLLLGLASMTMLLVDHDLQRSLDRLEHLLAAAREGLRRRWQAWRQHQAERRRQRREARRRRREERPTPASPPPPPEPRPAPEPAIGTTEGDAIPRHELLRELAQHETPPPEPAPPEPKPAEPRQPELIVRQGVEEERADRIDRPAELPATTALPPYTPPPIDLLDAPEAHERRIDYEELEANKRILLDKLATYNIEITSINAIVGPTVTLYELTPAPGVKISKITSLEDDLAMALAAPGIRMIAPIPGKSAIGVEIPNRHRELVRIRDVIGTARFRDAQMELPIALGKTIEGEVYLQDLTRLPHLLIAGATGSGKSVGLNALITGLLYACHPANLKFVMIDPKKIELQQYAAVVDHFLAMPEGAEEPIITDFTQALSVLKSCEKEMELRYDLLSKAGVRSIKDYNRRLKEGALSPDEGHRHLPYIVVIIDELADLMMTAGKDIEGPIARLAQMARAVGIHLVLATQRPSVDVITGLIKANFPARIAYQVATKVDSRTILDQNGAEGLVGNGDLLFMMGSQLVRLQGPFVSIDEVERVTGFIAEQPGPGPYWLPSIEDEREGETTAGSSDSYDELFEEAARIIVRSQQGSVSLLQRKLSIGYTRAARIVDQLEEAGIVGPFEGSKARRVLVQSEAELDELLRSLRASS
>NC_015966.1|WP_014067322.1|2021319_2022069_+|2-phosphosulfolactate-phosphatase
MNVEVFLTGSHVTEEDVEGRTVVVIDVLRASSTIITALANGARAVIPVADMDQAGKIAMNLDPSTYLLGGERDGDRIDGYHLGNSPLEYTPDVVEGKTIILNTTNGTRAIWNARNAEHLIVGSFLNADRVVQFVREVGLDVTIICAGRNNRVALDDALCAGLILHRLWEGREPEYVSDAAHIALTQYLHDRDRLADALRHSNHARWLIEKGYGADVEYCLQLDALPVLPYYRENRLVLYRERQPSESTG
>NC_015966.1|WP_014067321.1|2020102_2021230_+|glycine-cleavage-system-aminomethyltransferase-GcvT
MAETTLKRTPLYDRHVALGARMMGFGGFEMPVQYSSIIDEHLAVRRAAGLFDVSHMGEIFVRGPHAFDFVQHLITNDAARLYDGRALYTVMCTSEGGVVDDLLVYRFDAETYLLVVNAANIEKDFAWMQASNPMGAHLENRSDEIALLALQGPAAFEIARHFVPDLAPDNPRYYHFRVMEPGTFLDCRWAVLSHTGYTGEPGLEIYCHADEAVRVWDALLEVGQAHGLKPAGLGARDTLRLEAGYCLYGHELDESTNPLEAGLSWVVKFDKGDFIGREALLRVRENGPARRLIGLILEERGIPRAGYPITDEGGTSIGKVTSGTLSPVLQQGIALGYVPTRPDYTEPGRRLGVQIRGQNVPARVHKPPFVELHRK
>NC_015966.1|WP_014067332.1|2032082_2032289_-|hypothetical-protein
MFDSEPFRSPRFVLLGAVFLALLFGLVALMAEWVLTGTPQLTADVVRLSGLAFVGFLLVAALIRCRNN
>NC_015966.1|WP_014067333.1|2032338_2033769_-|sodium:proton-antiporter
MDGLVLLPPIVAIGLALGTRQVYLSLLVGLWLGTTLLEGGHPLLGLRRLGDELVAVFADAGNTRVVMFCLLVGGLIALMQASGGVQGFIAWAQRRGWGTSRRGAELLAWLVGLVIFVESSITSLVVGAVGRPFFDRLRLPREKLAFYCDATSAPVCMMIPLNGWGAYVLGLLAAQGISDGAVRLLAEGLLYNVFSWLTILFALLVAWTGWGFGPMRAAERRAAATGQLLRPGAQPLVAEEIAGLKPVEGAPCRASDFLIPLGVMVGMIFVGLWVTGEGNLMAGSGSTAVFWAVATAVAVAMALYALPRPLRGGRPVLSLARSTTLVLRGMSGLVGVTILVVLAFALGQVSRALEMGPYLVGLIDPNWPLWWLPALVFLVGCFVSFTLGSSWTTFAILIPVALPLAEGLGLPLPLMLGALLSGGIFGDYASPLSDTTIISSMAAACDHIDHVNTQLPYALLLAGVSLVVYLGLGLAL
>NC_015966.1|WP_014067334.1|2033781_2034372_-|thioredoxin-family-protein
MALTYSQEIALGTEAPPFNLPVVNPEADGLDKPTRSLEDFADARALVVVFTCNHCPYAQHIEDALIEVARVYQPKGVRFVAINANDPAQYPEDAPEEMARRARAKGYPFPYLFDETQEVARAYGALCTPDLYVFDANRRLVYHGRFDDTRPGQGRLATGADLKRALDELLETGKVTGPQYPSMGCNIKWKPGNEPR
>NC_015966.1|WP_029698451.1|2034445_2035297_-|zinc-metalloprotease-HtpX
MSNTLRTAALMALLIVLFVLIGEAIGGEQGMIVAFFFAVAMNFFSYWFSDKIVLMMYGAREVTREEAPELYDIVDRLRQRAGLPMPRVYVIPSEQPNAFATGRSPKHSAVAVTQGIVRLLNREELEGVIAHELAHIKHRDILISSIAATLAAAITMLARFAFFFGPAQDRDRGNALAGLLMLILAPLAAMLIQMAISRAREFAADRGGALICGKPRALARALEKLEAGVAHIPMDANPATAHMFIVHPFSGGGIARLFSTHPPTEERIRRLLELEQELAGARV
>NC_015966.1|WP_014067336.1|2035411_2035732_-|tetratricopeptide-repeat-protein
MDRLEQLLQFYREDPDDAFTRFALAQEYWKRGDVAQALHFFEGLVRDHPDYVGTYYHLARLYRELGRTEDALRTYRQGIEVARRVGDVKSLAELQDALMALELGEE
>NC_015966.1|WP_014067337.1|2035746_2036559_-|TPM-domain-containing-protein
MRRLGGRWLGWVLALLLASVALAQQIEVIPPSGQWVTDLADLLTPAEERMLSRKLATYADTTSTQIVIVTLPTLNGVPAADYAVELGRRWGVGQKEYDNGVVILVAREEREVFIATGYGLEGAIPDALAGRIVRDIIVPRFRRGDFYGGLSAAVDAIIAAAQGEFQPPPRAADDRGVWVNWAALFVLLVVLLFFLSAMCSGGGPPRGRKGARYPYRVYRREPDFPPVIIWGGGFGGGGGWSSGGGWGGGDFGGFSGGGGSFGGGGAGGHW
>NC_015966.1|WP_014067338.1|2036562_2037165_-|LemA-family-protein
MRSKGLLALVVVVLLLGMAGCAGCSAYNRMVEADEMVARAWADLQAQYQRRANLIPNLVRTVQASANFERETLEAVTNARARATSITLSVEDLSDPEKVRQFQEAQAQLSSALARLLAVAENYPQLQTTEAFRDLLVQLEGTENRIAVARRDYNEAVRRYNTLVRRFPTVLVASLTGFAPKQPFEAAESAQEAPEVEFDL
>NC_015966.1|WP_014067339.1|2037347_2039018_+|S41-family-peptidase
MKKSLRYTLPAVLLLALGILLGWNLQQAVSDTDTLASLRKLEEAFLTITQRYVDPVEPEPLAEEAIRSMLQELDPHSVYITAEEMKELRESYQGSFGGIGIWFEVVDDTARVVATISGGPSEAVGLQPGDRIIKIEDSSAVGLSSTEIQKRLKGPEGTKVRVTIRRLGVREPLEFTITRDRIPLYTVDAAYMLDKRTGYIRISRFAMTTYDEFLEHLDRLKRQGMERLVLDLRGNPGGIMEAAVEMVDELLPEGYTIVYTRGRVAQAEMTRRSTSGGRFETQPVIVLVDRNSASASEIVAGALQDNDRALIVGLRTFGKGLVQNQFPLSDGSVIQLTVARYYTPSGRLIQTPYHGGDLEDYYREKFADYETTVFHPEDYINEIPDSLKFKTVHGRTVFGGGGILPDVIVPPDTNSILLEVSRRNLPSTFIRTWFNQHEQAIRAQWNNRKEAFLTSFEVDDALWQAFLDYAREQGLFAADSAATHRFTVAQAEAHRHELSMLLKAYLAWQLFGREASIPLFNEIDPVLHEALKHWDRAEALAAYFAPKAGDTVRKGR
>NC_015966.1|WP_014067340.1|2039187_2039628_+|Hsp20/alpha-crystallin-family-protein
MAEVMRYTSPTTLLSELQREVDRLFENFFGGWLRPEVESAVWTPTVDLLETDDAYLIYMDLPGVNRDQVTITFENGTLQVSGERVQPEHKDAQYHRMERWYGRFFRSFNLGQNVNPDKIKAHFENGVLVIEAPKTEKSKPVRIKIS
>NC_015966.1|WP_012844319.1|2039718_2040417_-|phosphate-signaling-complex-protein-PhoU
MTVHRHIDDELLVLQRMLFEMADLVDEQMANAIDALLRRDLELAERVRARDDEVDAYELKIDRQCERILALHHPVAAELRMIITAVKVNTDLERIGDHCKNLAKHTPYVVQAPEALAQTRIEEMADASRAMLRQVQEAFLKRDRLLARQVLAEDLQIDRLHRENFEQLVRFGRQHPEHLEAVAHLITASKALERISDHAKNIAESVVFLIEGVDIRHRKLREPQAQEGERPL

Crispr_ID: NC_015966_8

• CRISPR_ID: NC_015966_8
• CRISPR_location: 2235489-2235580
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_015966_8

Consensus_repeat	Method
TCGGCATCCACCACACGCCCCCGGATCGTAC	CRISPRCasFinder

spacers of NC_015966_8

>8.1|2235520|30|NC_015966|CRISPRCasFinder
TGTCTATATCAACGTATTCCCTCTGGTGGA

CRISPR arrays and Neighbor proteins around NC_015966_8

CRISPR arrays

The CRISPR arrays of NC_015966_8

>merge|NC_015966|8|2235489-2235580|CRISPRCasFinder
TCGGCATCCACCACACGCCCCCGGATCGTACTGTCTATATCAACGTATTCCCTCTGGTGGATCGGCATCCACCACACGCCCCCGGATCGTAC

>NC_015966|8|8|2235489-2235580|CRISPRCasFinder
TCGGCATCCACCACACGCCCCCGGATCGTAC	TGTCTATATCAACGTATTCCCTCTGGTGGA
TCGGCATCCACCACACGCCCCCGGATCGTAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_012843428.1|2226109_2227006_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl|CDD|181386
NC_015966.1|WP_014067500.1|2244540_2244930_+|fluoride-efflux-transporter-CrcB	unknown	unknown	gnl|CDD|172710
NC_015966.1|WP_012843419.1|2237938_2238919_-|NAD(P)H-quinone-oxidoreductase	unknown	unknown	gnl|CDD|176180
NC_015966.1|WP_029736332.1|2233370_2234714_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NC_015966.1|WP_014067494.1|2229066_2230428_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB	unknown	unknown	gnl|CDD|237857
NC_015966.1|WP_012843425.1|2228509_2229058_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014067497.1|2239047_2239986_+|malate-dehydrogenase	unknown	unknown	gnl|CDD|133424
NC_015966.1|WP_012843413.1|2244926_2245271_+|DUF190-domain-containing-protein	unknown	unknown	gnl|CDD|376875
NC_015966.1|WP_155815923.1|2232363_2233515_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NC_015966.1|WP_012843417.1|2240111_2241047_+|cation-transporter	unknown	unknown	gnl|CDD|224151
NC_015966.1|WP_012843427.1|2227080_2227707_-|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl|CDD|225002
NC_015966.1|WP_014067496.1|2235764_2237321_-|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl|CDD|369639
NC_015966.1|WP_012843426.1|2227780_2228410_-|superoxide-dismutase	unknown	unknown	gnl|CDD|223678
NC_015966.1|WP_014067498.1|2241052_2244001_-|glycosyl-hydrolase	unknown	unknown	gnl|CDD|374209
NC_015966.1|WP_012843429.1|2222207_2225660_-|methylmalonyl-CoA-mutase-family-protein	unknown	unknown	gnl|CDD|239650
NC_015966.1|WP_014067501.1|2245236_2246871_+|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl|CDD|349937
NC_015966.1|WP_012843423.1|2230486_2230933_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014067495.1|2231018_2232344_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014067502.1|2247118_2248240_-|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NC_015966.1|WP_014067499.1|2244079_2244544_+|DUF1232-domain-containing-protein	unknown	unknown	gnl|CDD|225876

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_012843428.1|2226109_2227006_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl|CDD|181386	PRK08321, PRK08321, 1,4-dihydroxy-2-naphthoyl-CoA synthase.	0
NC_015966.1|WP_014067500.1|2244540_2244930_+|fluoride-efflux-transporter-CrcB	gnl|CDD|172710	PRK14222, PRK14222, fluoride efflux transporter CrcB.	3.41771e-26
NC_015966.1|WP_012843419.1|2237938_2238919_-|NAD(P)H-quinone-oxidoreductase	gnl|CDD|176180	cd05276, p53_inducible_oxidoreductase, PIG3 p53-inducible quinone oxidoreductase. PIG3 p53-inducible quinone oxidoreductase, a medium chain dehydrogenase/reductase family member, acts in the apoptotic pathway. PIG3 reduces ortho-quinones, but its apoptotic activity has been attributed to oxidative stress generation, since overexpression of PIG3 accumulates reactive oxygen species. PIG3 resembles the MDR family member quinone reductases, which catalyze the reduction of quinone to hydroxyquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NC_015966.1|WP_029736332.1|2233370_2234714_-|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	8.30865e-32
NC_015966.1|WP_014067494.1|2229066_2230428_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB	gnl|CDD|237857	PRK14902, PRK14902, 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB.	7.18179e-156
NC_015966.1|WP_014067497.1|2239047_2239986_+|malate-dehydrogenase	gnl|CDD|133424	cd01339, LDH-like_MDH, L-lactate dehydrogenase-like malate dehydrogenase proteins. Members of this subfamily have an LDH-like structure and an MDH enzymatic activity. Some members, like MJ0490 from Methanococcus jannaschii, exhibit both MDH and LDH activities. Tetrameric MDHs, including those from phototrophic bacteria, are more similar to LDHs than to other MDHs. LDH catalyzes the last step of glycolysis in which pyruvate is converted to L-lactate. MDH is one of the key enzymes in the citric acid cycle, facilitating both the conversion of malate to oxaloacetate and replenishing levels of oxalacetate by reductive carboxylation of pyruvate. The LDH-like MDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
NC_015966.1|WP_012843413.1|2244926_2245271_+|DUF190-domain-containing-protein	gnl|CDD|376875	pfam02641, DUF190, Uncharacterized ACR, COG1993.	1.15763e-52
NC_015966.1|WP_155815923.1|2232363_2233515_-|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	1.58401e-20
NC_015966.1|WP_012843417.1|2240111_2241047_+|cation-transporter	gnl|CDD|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	8.09782e-97
NC_015966.1|WP_012843427.1|2227080_2227707_-|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl|CDD|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	1.13649e-16
NC_015966.1|WP_014067496.1|2235764_2237321_-|pyridine-nucleotide-disulfide-oxidoreductase	gnl|CDD|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	2.72216e-51
NC_015966.1|WP_012843426.1|2227780_2228410_-|superoxide-dismutase	gnl|CDD|223678	COG0605, SodA, Superoxide dismutase [Inorganic ion transport and metabolism].	1.78441e-114
NC_015966.1|WP_012843429.1|2222207_2225660_-|methylmalonyl-CoA-mutase-family-protein	gnl|CDD|239650	cd03678, MM_CoA_mutase_1, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, unknown subfamily 1; composed of uncharacterized bacterial proteins containing a C-terminal MCM domain. MCM catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. The reaction proceeds via radical intermediates beginning with a substrate-induced homolytic cleavage of the Co-C bond of coenzyme B12 to produce cob(II)alamin and the deoxyadenosyl radical. MCM plays an important role in the conversion of propionyl-CoA to succinyl-CoA during the degradation of propionate for the Krebs cycle. In some bacteria, MCM is involved in the reverse metabolic reaction, the rearrangement of succinyl-CoA to methylmalonyl-CoA. Members of this subfamily also contain an N-terminal coenzyme B12 binding domain followed by a domain similar to the E. coli ArgK membrane ATPase.	0
NC_015966.1|WP_014067501.1|2245236_2246871_+|M20/M25/M40-family-metallo-hydrolase	gnl|CDD|349937	cd08015, M28_like, M28 Zn-peptidase-like; uncharacterized subfamily. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions.	2.30452e-116
NC_015966.1|WP_014067498.1|2241052_2244001_-|glycosyl-hydrolase	gnl|CDD|374209	pfam15902, Sortilin-Vps10, Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1.	2.58883e-10
NC_015966.1|WP_014067502.1|2247118_2248240_-|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	1.82628e-54
NC_015966.1|WP_014067499.1|2244079_2244544_+|DUF1232-domain-containing-protein	gnl|CDD|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	4.38593e-13

Protein sequences

>NC_015966.1|WP_029736332.1|2233370_2234714_-|TonB-dependent-receptor
MSKYFGRQIRPYELVRTNFMHEMFETGYHQAYSASVSGGTPGVTYFVNLRWSDEDGPFGAKDGRWYPPGVRTRSADINRLAQASATVNIFPSDKLRLGISTGLTRRHYETPNNNNNIYAAFTLAQFSKPELVRYNNQTGSPAFMTVNEGLQQTYTQDVDRFFGSLNLNYRPSRPLMVDATFGIDVVNQLSREVFPFRWNIDNFSGYNPEGVRRIDDLNALDITADIKATHRVQLSSSLESTFILGTQGFITRRIDESAEGRRFPGPGIDVTGGAAEQEVFESYLEVVNLGIFAQEQIGFNDYLFLTVGGRLDANSAFGSEFDAVFYPKASLSFIPSDAPFWRPLGPISSLRLRAAVGQSGLQPGAFDALTTYVPVASSSGPGIVPGNLGNPELKPEISTEWEVGMELGLLQPCRPPTGIERLPMPWSTSNSPLREASGQASLRILVN
>NC_015966.1|WP_155815923.1|2232363_2233515_-|TonB-dependent-receptor
MGSGHGARIVAALQATYWDRTVTDALVDKQFPVTGGFRASQLTNIGELKGRGIELGFQGTIYSSEQFSVDLFAGASYLWEQVTDMGGAPPIKVGGSYPRYRNFIIEGYAPGAHFGAKLLPTDANHLPIDFNGDGQPDSRDEVLAYLATLTPEDLINASNGQVNMPSSVGLVLLADEDGDGDLLDHYLGKPTPDWQGSFGATIRFLRNFRLYTAFEFKAGNYYVNNLTFAFRQANAVIGRNLPWSAEVVRDYATGGVDANGNPMNDPQVRLRALERWLNEVLALAPFSGLDTIKPADFLRWRELSLTYDVPRSQLQRLWGIDRLSFTLGVRNLALWTRYDGPDPEVNAVGRGSGSQLDQNYLDGVDAFGFVMPRRVTFTVRFGF
>NC_015966.1|WP_014067495.1|2231018_2232344_-|hypothetical-protein
MRYDKSLWIGLLVFSLGLSIAGCNLLDVNNPNNLVEEDLGNPAAAEPMVNGVEAAVTRAVQAILTPYSTATDELVWVGSRDAWQQLDFGNVDDPFNEFTDAAFPYVAEARWWADAVIARLEEFREQGALSNPIVLARAYLYGAIIYVTIADMFDDFAFSDRMESAPPIGRDGLPQVYDTAINYLDRALAIAEARNNTALQGQILMFRARAKYSKALRAMLRPGQVQVNGLVNDAGAVADAQAALAVVDPEARVILDMDPNAPDLVMGDLSLGDQVNSRLEMRIGDTYIQPTPNNKQTQAVIFKDIIDTEVVHPFVEQEITAFHAAGLYPDMTVASEREMHLILAEAMLASGDVNGFATHINHLRTRDGLTPYDPNSSGIEPIEMLRFSRQAYLFLQGRRLADHYRFNDPSPEWRPDGTAMRQPGTFFPITIIERRANPYID
>NC_015966.1|WP_012843423.1|2230486_2230933_-|hypothetical-protein
MRGLIVLGITGCLLLGACDLFRGQDAPERARLRIEGTTDSTLTLVTSTNFLLQRTAVLDESGTPRRDTLLVYFLEADTLQITLPYSGEFDIRLRERFFARLSPGVAGVWMRVWIDDRLRYDTRPEETLPLLQFVYYRVKGTPPYNEIF
>NC_015966.1|WP_014067494.1|2229066_2230428_-|16S-rRNA-(cytosine(967)-C(5))-methyltransferase-RsmB
MPKVRGLRKRLDPARREAVRLLERIENDQAYVNRLMSAGLTDELEPEAGRRATEYVAGVTRWRRWLDFLLAQNYRGRYDSMEPRLRQILRLGLYELLFTDTPPYAALNEAVELARRLVRPQAGAVVNAVLRSLLRQRDFLPQPQTGDPVEDLAIRYSHPTWIVQRWLARYGPADTEALLRYNNERPWFGVRVRTDRISRHVVLHRLADRGLEAEPSPVLDDFIRVQRLGPLLEDRLIEKGLLAVQDESAGLAVRLLDPHPDETIVDACAAPGGKTTYIATRMRDHGRVLAFDVHPKRTELIRRAALQQGLTSIVAEALDLRQVSERYPELQADRVLLDVPCSGLGVLAKRADLRWHRRPEELDELVRLQDELLETAARLVRPGGVLVYSTCTIEPEENEARVRAFLARHPEFTVERADAWVPAEMVTDEGFFATWPPRDRMDGAFAARLRRTA
>NC_015966.1|WP_012843425.1|2228509_2229058_-|hypothetical-protein
MEELIRELIPHAPQWGLFVAPEIPEDRLRGALADYAQGVAPHEVLALYDATWMGTGRDGAVFLRDRFVFQNLDLEPPQTVRYEDLVGVELKRRLLGGRRIVLQVNRGRATFTLSMDFSGKPKAAPYVARFLQEAMLRAPTFPKDPSGQTDHEAVQAALQQLLETGKLNRRDYERLLEVLRSG
>NC_015966.1|WP_012843426.1|2227780_2228410_-|superoxide-dismutase
MAFTLPPLPYPYDALEPYVDAQTMEIHHTKHHQGYVNNLNKALEGYPELQNKSIEELLRGINEIPEAIRTAVRNNGGGHANHSLFWTIMKPNGGGEPTGELAEAIKATFGSFEAFKEKFSAEAAGRFGSGWAWLVVDENGKLQVYSTPNQDSPYMQGHTPILGLDVWEHAYYLKYQNRRAEYIQNWWNVVNWDQVAQYYKEALAKVAAA
>NC_015966.1|WP_012843427.1|2227080_2227707_-|4'-phosphopantetheinyl-transferase-superfamily-protein
MELPESISWHWLRYDLSCEPRWRSWLSEDEHRRLAGFRRVQRRRAFLLGRAAARQLLAERLGVTPERVPLVARPDEPPQVPGTGLFVSIAHADEVALAAVAPHPIGADLERIRPRPPELYRYVLHPDEYSLLRHFGDDPGRAVIWCWAFKEAVLKGLGVGLRCSPRRLRLALETATCGRVLLEDGTSWQVWASERDGYVRALAWPENR
>NC_015966.1|WP_012843428.1|2226109_2227006_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MVSAIFDPDRWVEVEGFQFEDITYHRAKDQGTVRIAFNRPEVLNAFRPKTVDELYQALDHARQTPDVGVVLLTGNGPSKKHGKWAFSAGGDQRVRGPSGYQYEEGDDSPAAKARMGRLHILEVQRLIRFMPKVVIAVVSGWAVGGGHSLHVVCDLTIASREHALFKQTDPDVASFDGGFGSAYLARMVGQKRAREIFFLGRTYTAEEAYQMGMVNAVVPHEKLEEVALEWAAEINRKSPTAIRMLKYAFNLIDDGLIGQQLFAGEATRLAYMTEEAREGRDAFLEKRKPDYSKFPWYY
>NC_015966.1|WP_012843429.1|2222207_2225660_-|methylmalonyl-CoA-mutase-family-protein
METRVYKPKHRIRFVTAASLFDGHDAAINLIRRLLQASGAEVIHLGHNRSVHEIVETAIQEDVQGIAVSSYQGGHMEFFKYMIDLLRERGASHIKVFGGGGGVIVPEEIRELEAYGVCKIFSPEDGLRMGLQGMVNYMLEQCDFPTVRQLEAEALERVRQRDKKALARALTAIESRLLEHVPAHLVPEPAGGDGAPAAEVRTAPVVGITGTGGAGKSTLTDELIRRFLNDFEDIHIAVLSVDPTRRRTGGALLGDRIRMNALYGEHGDRVYMRSFATRQAHRSISESLQEAIDVCRAAGFDLIFVETAGIGQSDTEIVDLADLTIYVMTQDYGAPTQLEKIGMLDLADLIALNKFEKRGSQDALRDIRKQVQRNRGAFDQPLEAMPVFPTMASHFNDPGTTRLYLALLDLLNERFRFGRTSRLFKPEELPEVDPEKLAIIPPKRERYLGEIVETCRNYRKWVEEQVTYARKWGEAVGARRQVERWAPEDRELLLERLDQMIRHWWDKLDARCKRILEAWDATAERYRQETFTYKVRDKEITTPLYHTSLAGTKVPRVALPRYEDPGERLRFALLENLPGYFPYTAGVYPFKRTEEEPTRMFAGEGTPERTNRRFHYISEGMSARRLSTAFDSVTLYGRDPDERPDIYGKIGNAGVSICTLDDMKKLYSGFNLCDPKTSVSMTINGPAPMILAMFLNTAIDQQVEYYLREIGRWEEVERAIAERLGDERPRYVPFGPQGRLDSLPPTHDGTGLGLLGTSGAELVEWGLLDRETYENIKARALSVVRGTVQADILKEDQAQNTCIFSTEFALRLMGDVQQYFIDHKVRNFYSVSISGYHIAEAGANPITQLAFTLANGFTYVEYYLSRGMHIDDFAPNLSFFFSNGMDPEYSVIGRVARRIWAVVMRDKYGANERSQKLKYHIQTSGRSLHAKEIAFNDIRTTLQALMAIYDNCNSLHTNAYDEAITTPTEESVRRAIAIQLIINKEFGLAKNENPLQGSFIIEELTDLVEEAVLQEFERIDRRGGVLGAMESMYQRGKIQEESLLYERKKHSGELPIIGVNTFLPKNGESHDAPTALMRSHEEEKRHQIENLRAFQRRNAHRAPRMLERLQQVARRGENVFAELMETVRYCSLGQITQALFEVGGEYRRNM
>NC_015966.1|WP_014067496.1|2235764_2237321_-|pyridine-nucleotide-disulfide-oxidoreductase
MPIYPVARVDELADGQMKQVQAGETELLLVRLDGQFYALGARCTHYGAPLATGALHGERIICPWHHACFHARTGEHLEPPGMDHLPRFPVRVEDDQVLVELPDTVEGRRAPTLARRDPQEARTCVVVGSGCAGAYAVEAARAQGFRGRVLWVAGGEFPPIDRPNLSKEYLAGEAPEEWMPLRDPSFYEAADIEVVQGRPAAALDAAAKTITLADGEVLRYDVAVVAPGARPRRLEVPGAELAGIFTLRTIEDSRAIRAAAREARRAVVVGASFIGMEVAQSLRHLGLEVTVVAPESVPFERTLGVEVGRVLQTLHEENGVAFRLGHTVQAFEGTDRVQQVVLNGGSRLAAELVVVGVGVQPATDFVQGVQKAPDGSIIVDAFLQAAEGLFVAGDAARFPDWRTGAPIRIEHWRLAAQHGRLAGANAAGARRAYRGVPFFWTRQFGVSLQYLGYVDAWDEVVLDGDPSARKFLAFYLRGEQVWAVAGMGRGYEMARLHGLLLEEGLPVLESVRSYLLSR
>NC_015966.1|WP_012843419.1|2237938_2238919_-|NAD(P)H-quinone-oxidoreductase
MRAILVSEPGGPEKLYLGEYPTPAPGPGELLVRVRATSLNRADLLQREGKYPPPPGASPILGLDVAGTVAALGPGVTGWQVGDRVFGLVEGGGYAEYAVLPAGMAMRIPDNLSFEEAAAVPEVFLTAYQALCWLGQLQRSEHVLIHAGASGVGTAAIQLARRLGAHVHITASASKHEICRALGAETTIDYHTENFAARVQEATGGTGAHVIIDFVGAPYLEPNLQCLAVDGRIVLLATMGGSRVASFDLRLLFARRAHLMASTLRNRPRDYKVRLTQEFAERFLNDFAEGRLRPVIDRIYDWTEVAEAHRRMEANLNVGKIVLRIA
>NC_015966.1|WP_014067497.1|2239047_2239986_+|malate-dehydrogenase
MKVTVIGAGNVGATVAECVARKDMVKEVVLVDIVEGLPQGKALDMQEAAPIHGYDTRIIGTNDYKDTEGSDICVITAGSPRKPGMSRDDLLAINAKIVRSVTEQFVKGSPNAIIIVVSNPLDVMTYVAYKTSGFPSHRVMGMAGVLDTARFRTFIALELGVSVRDVQALLMGGHGDSMVPLPRYATVSGIPITQLLSREKIDAIVERTKFGGGEIVKLMGTSAWYAPGAAAAEMVEAIVKDSKRILPCAAYVNGQYGLKDLFIGVPVRLGRQGVEEIIEVELNDEERKLLEASAEHVRKGIQDLERVETNAG
>NC_015966.1|WP_012843417.1|2240111_2241047_+|cation-transporter
MAHAHSHHHPHPHPGSQRRLLLSVLLNLLISVAEVIGGLLSGSLALISDAVHNLNDTASIAISYVARKLSHRAPSASKTFGYRRAEIIGAFANLITLVVIALFLIKEAVDRLLNPQPINAPVLLTVATIGLLANVFTAILLYRDARESLNVRSAFLHIVSDAVSSVAVILGGFTILFWDVYWVDPVVTIGIAVYIGYLSWKMLRQTTHILMEGTPENLDPRHIAADLRQMAHVRDVHHVHIWQLDEHHLAFEAHVVVDEADLPRMEQIKRALKQRLREQYGIGHVTLEFESHPCCEEASAPPCHDPLPARR
>NC_015966.1|WP_014067498.1|2241052_2244001_-|glycosyl-hydrolase
MLWHSSLFGLLFGLVLTTAQAQERAPVPPTPADVRLRSYQERMARVERSLVRNVPFRGIGPTIMSGRVVDVDVNPDDPTEFYVAYASGGLWKTENNGISFQPLFDREATMTIGDIAVDWAHGEVIWVGTGESNSSRSSYAGTGIYRSTDGGRTWEHLGLAETHHIGRIVIHPDDPNTVWVAAVGHLYSPNPERGIYKTTDGGRTWRRVLYVDDNTGGIDLVIDPTNPNVLYAAMWHRERRAWNFVEAGPGSGIFKSTDGGETWQRLNVEGSGFPTGEGVGRIGLAIYPKNPQILYALLDNQYHRPEEEAEQPALTKEDFLEMSREAFLALSDDSLEAFLRENGFPREYTATRVKEMVRRGEIEPRALYDYLTDANQELFETPVIGAEVYRSDDGGRTWHRTHEGYLDNVYFSYGYYFGQIRVDPNDPDHVYIMGVPMLVSDDGGRTWRSIDRENVHVDHHALWVNPNRPGHLVNGNDGGVNLTYDDGRTWFKANTPPVGQFYAVAVDSARPYNVYGGLQDNGVWVGPSTYEFSYEWYAEGRYPYERLLGGDGMQVQVDPRTNDIVYTGFQFGNYFRIERKTGRRVPIKPRHKLGERPLRFNWETPIFLSRHHPDILYLGSNKLHRSFNRGDDWETISGDLTRGGRKGDVPYGTLTTIAESELRFGLIYVGSDDGLVHVTRDGGVTWTRISDELPQHLWVSHVEPSQHVESRVYVALNGYRWDDFTPYLYRSEDYGLHWTRIGTDLPYEPINVVREDPYNPDILYVGTDGGLYVSLDGGRSFMPFYEGLPHAPVHDLVIHKRARDLVVATHGRSLYVADLEEIEQLTPALLARPLHVFAIDTVRHNPNWGRIRAAWMPPDTPAVRIPYYSREAGPVTIRVLTEDDLLLAVRTDTAEVGLNYPVYDLTIDTTQVAAFNARRDEKAQVRAADNGRYYLPPGTYMVELVRGAATARGRLVVQRSRRDRFQMLPRVEPEMERYLERY
>NC_015966.1|WP_014067499.1|2244079_2244544_+|DUF1232-domain-containing-protein
MPLPDLEVREMSPEALSRPPLHTRAFELALRTARRSLARRSRLMRLVLHASRRLARREAALVQVRDDLHTLLRMVQAWMRREYRIVPWRSLLYGVAALAYFVNPADLLPDALLGLGLVDDVAVIAAVARAIQADLERFRQWEALRSRTNGNESA
>NC_015966.1|WP_014067500.1|2244540_2244930_+|fluoride-efflux-transporter-CrcB
MKLLLIALGGALGALARYALSGLVYAWLGPAFPWGTLVVNLTGCYGLGLLWALSEAVPLPTSIPPLVFVGFFGAFTTFSTYGLESFNLLRDGELVLALLNLLGSSLAGLLCVALGFLTARLLLHLGGMP
>NC_015966.1|WP_012843413.1|2244926_2245271_+|DUF190-domain-containing-protein
MTKLPAEGVLLRIFIGETDRYHGRPLYEQIVLKARELNLAGATVLRGIMGFGASSRVHTAKLLRLSEDLPVVVEIVDTEENIQKILPFLDEVVQEGLITMEKAHVIRYRHRSED
>NC_015966.1|WP_014067501.1|2245236_2246871_+|M20/M25/M40-family-metallo-hydrolase
MLSAIATVRKIKHTGLLLLALLWAIPLRAQEPVDTLAVRLIREEGLERSQVMETMFWLTDVYGPRLTGSPLLDSAMAWAVRRLESWGLANVHREPWGPFGRGWTLHHVRAEVTAPVAFPVLAYPKAWSPDIDGPVTAEVVRFDVEDTSAFAAYRGKLRGKIVLLEPPRELKEPFEPLARRRDAEDLLALANAARPEGGGRRYSAEVLRQLELAQRRLQFLYEEAPLAILDRGYRGDYGTVFVDAADVPAAPGTPWYERPGPWEPGVRVIPQFTVAVEHYNRIYRLLERGFRVEMTLDLDVSFNDDDPYEYNLIAELPGTDPRIGDEVVMLGAHFDSWHAGTGATDNAAGSAVMMEAMRILKAVYDWLGRGPRRTIRLALWTGEEQGLLGSRAYVDQHFAELRGWGQPPGRLKPEHEKFSVYFNLDNGGGKIRGVYLQGNEAVAPIFRAWLAPFHDLGAATLSLRNTGGTDHLSFDAVGLPGFQFIQDHLAYGTRTHHSNMDVFDHVIEDDLKQAATIIAAFAYHAAERDTRIPRKPLPMPEGTN
>NC_015966.1|WP_014067502.1|2247118_2248240_-|mechanosensitive-ion-channel-family-protein
MLLGLQLNELGQTMIAGAPLLEWLKAIGVWAALSVVFIVVQRVLASRIEALAARTRTNIDNVIANVLRQTRAYFLVGLAFYAAVAIVQLPRPVVQWGGRIAFVLLLLQLIRWGSGLITFYVERYRQQKLEEDSAAVTSMQALGFIGRLVLWTIVLLVALDNFGVDITALIASVGIAGVAIGLAVQNILGDLFASLSIVLDKPFVVGDFIIIDNYMGTVEHIGLKSTRIRSLTGEQLVFSNSDLLNSRIRNYKRMRERRIVFTVGVVYQTPKEKLEKIPQIIREIIEAQENVRFDRAHFKEFGPSSLNFEVVYWVLDPDYTLYMNIQQAINLALFERFAQEGIEFAHPTQTLFVYPMKPVEVASPQDTDARARA

Crispr_ID: NC_015966_9

• CRISPR_ID: NC_015966_9
• CRISPR_location: 2600014-2600099
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_015966_9

Consensus_repeat	Method
GAACGTTCCGGCGCCGAGGTCCG	CRISPRCasFinder

spacers of NC_015966_9

>9.1|2600037|40|NC_015966|CRISPRCasFinder
CACCTGCGGCGGAGGGGGCGTCGGGCGAATCACCGTTCGC

CRISPR arrays and Neighbor proteins around NC_015966_9

CRISPR arrays

The CRISPR arrays of NC_015966_9

>merge|NC_015966|9|2600014-2600099|CRISPRCasFinder
GAACGTTCCGGCGCCGAGGTCCGCACCTGCGGCGGAGGGGGCGTCGGGCGAATCACCGTTCGCGAACGCTCCGGCGCCGAGGTCCG

>NC_015966|9|9|2600014-2600099|CRISPRCasFinder
GAACGTTCCGGCGCCGAGGTCCG	CACCTGCGGCGGAGGGGGCGTCGGGCGAATCACCGTTCGC
GAACGCTCCGGCGCCGAGGTCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_015966.1|WP_012844756.1|2596703_2597069_+|chorismate-mutase	unknown	unknown	gnl|CDD|376623
NC_015966.1|WP_081472084.1|2594494_2594965_-|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379163
NC_015966.1|WP_014067759.1|2606522_2607176_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NC_015966.1|WP_014067757.1|2603049_2605494_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|372685
NC_015966.1|WP_014067748.1|2593055_2593433_-|DUF423-domain-containing-protein	unknown	unknown	gnl|CDD|225238
NC_015966.1|WP_155815996.1|2612013_2612991_-|DctP-family-TRAP-transporter-solute-binding-subunit	unknown	unknown	gnl|CDD|270389
NC_015966.1|WP_014067760.1|2607252_2608281_-|sugar-kinase	unknown	unknown	gnl|CDD|238571
NC_015966.1|WP_014067752.1|2595660_2596680_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	unknown	unknown	gnl|CDD|236585
NC_015966.1|WP_014067753.1|2597065_2598109_+|endolytic-transglycosylase-MltG	unknown	unknown	gnl|CDD|376862
NC_015966.1|WP_014067747.1|2592705_2593059_+|hypothetical-protein	unknown	unknown	gnl|CDD|223652
NC_015966.1|WP_014067751.1|2594999_2595503_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014067756.1|2601438_2602929_+|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236327
NC_015966.1|WP_014067764.1|2611499_2612012_-|TRAP-transporter-small-permease	unknown	unknown	gnl|CDD|225632
NC_015966.1|WP_029933252.1|2598083_2599691_-|hypothetical-protein	unknown	unknown	unknown
NC_015966.1|WP_014067762.1|2608950_2610159_-|D-galactonate-dehydratase-family-protein	unknown	unknown	gnl|CDD|237901
NC_015966.1|WP_014067763.1|2610185_2611487_-|TRAP-transporter-large-permease	unknown	unknown	gnl|CDD|224509
NC_015966.1|WP_014067761.1|2608299_2608944_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl|CDD|180618
NC_015966.1|WP_043760916.1|2605556_2606441_-|hypothetical-protein	unknown	unknown	gnl|CDD|271320
NC_015966.1|WP_014067750.1|2594014_2594473_-|ribosome-silencing-factor	unknown	unknown	gnl|CDD|376779
NC_015966.1|WP_155815995.1|2593501_2593972_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_015966.1|WP_012844756.1|2596703_2597069_+|chorismate-mutase	gnl|CDD|376623	pfam01817, CM_2, Chorismate mutase type II. Chorismate mutase EC:5.4.99.5 catalyzes the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine.	5.2373e-22
NC_015966.1|WP_081472084.1|2594494_2594965_-|LytR-C-terminal-domain-containing-protein	gnl|CDD|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	1.57659e-15
NC_015966.1|WP_014067759.1|2606522_2607176_-|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	2.31641e-14
NC_015966.1|WP_155815996.1|2612013_2612991_-|DctP-family-TRAP-transporter-solute-binding-subunit	gnl|CDD|270389	cd13671, PBP2_TRAP_SBP_like_3, Uncharacterized substrate-binding protein of the Tripartite ATP-independent Periplasmic transporter family; the type 2 periplasmic-binding protein fold. This subfamily includes uncharacterized periplasmic substrate-binding proteins similar to TRAP transport systems such as SiaP (a sialic acid binding virulence factor) and TeaA (an ectoine binding protein). TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.36186e-157
NC_015966.1|WP_014067748.1|2593055_2593433_-|DUF423-domain-containing-protein	gnl|CDD|225238	COG2363, COG2363, Uncharacterized small membrane protein [Function unknown].	2.61124e-29
NC_015966.1|WP_014067760.1|2607252_2608281_-|sugar-kinase	gnl|CDD|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	1.10196e-98
NC_015966.1|WP_014067757.1|2603049_2605494_+|TonB-dependent-receptor	gnl|CDD|372685	pfam13715, CarbopepD_reg_2, CarboxypepD_reg-like domain. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.	2.49562e-25
NC_015966.1|WP_014067753.1|2597065_2598109_+|endolytic-transglycosylase-MltG	gnl|CDD|376862	pfam02618, YceG, YceG-like family. This family of proteins is found in bacteria. Proteins in this family are typically between 332 and 389 amino acids in length. This family was previously incorrectly annotated and names as aminodeoxychorismate lyase. The structure of YceG was solved by X-ray crystallography.	1.34588e-111
NC_015966.1|WP_014067752.1|2595660_2596680_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD	gnl|CDD|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
NC_015966.1|WP_014067756.1|2601438_2602929_+|proline--tRNA-ligase	gnl|CDD|236327	PRK08661, PRK08661, prolyl-tRNA synthetase; Provisional.	0
NC_015966.1|WP_014067764.1|2611499_2612012_-|TRAP-transporter-small-permease	gnl|CDD|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	2.4546e-31
NC_015966.1|WP_014067762.1|2608950_2610159_-|D-galactonate-dehydratase-family-protein	gnl|CDD|237901	PRK15072, PRK15072, D-galactonate dehydratase family protein.	0
NC_015966.1|WP_014067763.1|2610185_2611487_-|TRAP-transporter-large-permease	gnl|CDD|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	1.38233e-133
NC_015966.1|WP_014067761.1|2608299_2608944_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl|CDD|180618	PRK06552, PRK06552, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	4.43422e-77
NC_015966.1|WP_014067747.1|2592705_2593059_+|hypothetical-protein	gnl|CDD|223652	COG0579, COG0579, Predicted dehydrogenase [General function prediction only].	0.00549368
NC_015966.1|WP_043760916.1|2605556_2606441_-|hypothetical-protein	gnl|CDD|271320	cd05819, NHL, NHL repeat unit of beta-propeller proteins. The NHL(NCL-1, HT2A and LIN-41)-repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures. The repeats have a catalytic activity in Peptidyl-glycine alpha-amidating monooxygenase; proteolysis has shown that the Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) activity is localized to the repeats. Tripartite motif-containing protein 32 interacts with the activation domain of Tat. This interaction is mediated by the NHL repeats.	4.96065e-10
NC_015966.1|WP_014067750.1|2594014_2594473_-|ribosome-silencing-factor	gnl|CDD|376779	pfam02410, RsfS, Ribosomal silencing factor during starvation. This family is expressed by almost all bacterial and eukaryotic genomes but not by archaea. Its function is to down-regulate protein synthesis under conditions of nutrient shortage, and it does this by binding to protein L14 of the large ribosomal subunit, thus acting as a ribosomal silencing factor (RsfS) by blocking the joining of the ribosomal subunits. This family is structurally homologous to nucleotidyltransferases.	3.67515e-46

Protein sequences

>NC_015966.1|WP_029933252.1|2598083_2599691_-|hypothetical-protein
MRTMKYAVRSLSGGLFLLLMLALQAHAQTVDDAWRFSQRLPGVGARLTAMGGASAAGLADYGALFSNPAGLGYYRASEVSGGLTWLNARDAATYHVPGNRFDWESELRATNLDHLVAVYKVPTVRGSLVLGMAYARVADFTRRLYFQGDNDANSITDAYLPYPDEYTVTSGGELQFNSDIPFIAYQAGAIEFLPSEYEAGRYPFYQAVAPGTTIRQTGEVTEEGGLHELSFGGAVEAAPNLFLGLSVGIVTGSYRFERRYEEDDFRNENTPDLYAVAVEGGFLYGFDYLRAQDYFESDLQGFSVRAGLSAQLSPSWRLGVGVETPVFFSVQEDYGTQLETFFDEGGSLRYGGQPGDAGTGSFDYEIRTPWRLRAGVAYQTRQLHVGLDLELIDWSQMRFDASTNRSFIQDLNRQVRDTMEPVVNTRLGLAYQMGGATLYGGVAVFPDPHKSEIREAEADRRRVFGSLGASIQLAESFRLNIGWAQEQFDDYYQPYGDVERPPYVREEVRRNRFVIGLTYTFQPPRARATRPPRRR
>NC_015966.1|WP_014067753.1|2597065_2598109_+|endolytic-transglycosylase-MltG
MKRWIAGAALVLLLLAGGLAWIALAPNTPSFEGARGVKIPRAARFEQVVDSLQAAGILRHRASFVWLARLTGWHRQIKAGYYTFEAGASNYHLLSVLRRGLQTPVRVTIPPGSRPEVVAAVVCRALACAPDSLLAALRDSSLAAELGTDTLHLFGRLLPDTYFFYWLTDPRTVIRRVHQHFLDFFTPERRARADSLGLSIDEVVTLASIVEWEAGPEERPRVAGVYLNRLRRDMPLQADPTVQYAVLQLEGQKRRLLFADYQIDHPYNTYRFRGLPPGPITNPSPDAIDAVLHAERHDYLYFVADGEGRHVFSRTFREHVRAANRYRRLMEQRRRQARDTTDGGADG
>NC_015966.1|WP_012844756.1|2596703_2597069_+|chorismate-mutase
MSLEQLHSAIDHAQNHRPELPESPTEADMIPWRRRIDEIDRAILRLLNERARCANIIGYIKKKLGLPVYVPEREEEVLRNVLAANEGPLSNEAVRRLFERVIDETRALERQKYQDLPPEAE
>NC_015966.1|WP_014067752.1|2595660_2596680_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-transferase-subunit-TsaD
MITEARTILGIETSCDDTAAAVVVEGKLRSNVVASQQATHLRYGGVVPELASRDHQRRIVPVVRQALQEAGLTPRDLDAVAVTYGPGLVGSLLVGLSFAKAFALGLGRPLIGVNHLEGHIYSVFIEPPSPPFPYLCLIVSGGHTQLMRVDEGFRHTLLGRTRDDAAGEAFDKVARLLGLGYPGGPEIDRLARQGDPNFVTFPRPRLEGYDFSFSGLKTAVRYYLDQFSEAERARLLAQHRADLCAAFQQAVVDVLIDALRRAIQDTGLRHVAIVGGVSANSALRAAAQALAEELDVRLYIPPLAYCMDNAAMIAITGYFKARAGLESPLTLAAVPALTV
>NC_015966.1|WP_014067751.1|2594999_2595503_-|hypothetical-protein
MRKTFLLIGLVVLLGVTVPAQAQLRADVSSAVQRAPIRLYNPGTGFSLSDLFSPEHFRMQHSYEMSMGTIGGYSYSLGVYTNSMLWQFSDKLAARVDIGVAHSPFGGSLGLNRRPQIFLRNAEIAYRPRENMLFQFTVRQSPYGYFMAPYGYYPFRSSERALFWNDR
>NC_015966.1|WP_081472084.1|2594494_2594965_-|LytR-C-terminal-domain-containing-protein
MTKKTRRREKRRSRRLENLLLILLVGSVGVLLYALGVRLLAPRVDPVRGANSAHLVGDIIQLEVRNGCGVDGVAARTTRYLRAHGFDVVEVGDYTSFDVPYSMVIDRVGDLEAARKVAAVLGIPEERVRQQIQPDLFLDASVIIGKDYAQLAPFQE
>NC_015966.1|WP_014067750.1|2594014_2594473_-|ribosome-silencing-factor
MTKLQTKGMQSDRRHRAHYPSRVLARHAVDAALDKKAQDLVVMDMRQVSGVADYFVLCTGQSDLQIRAIAEAIEERIEQHCQERPWHVEGREHLQWVVLDYVDVVVHIFTPEKRAFYALERLWGDAPQEQVAEDRSGADVQLLQEPVATAAG
>NC_015966.1|WP_155815995.1|2593501_2593972_-|hypothetical-protein
MLALWSACTGPRLLNPDDRFGHRYTGQAPDGRVTLTLASPDSGASWRYPVPTDTVHVRPGPFRPDLLPAMQAVPVELLIKGSLPDACSELDSVAQERTGHLLHVQLWMRRPQRRRCRPVVRPFRFYLMLADSLAPGSYTLKLNGRVFTFEIRVPEE
>NC_015966.1|WP_014067748.1|2593055_2593433_-|DUF423-domain-containing-protein
MARTFLVLGAVLAGLAVALGAFAAHGLAPHVSPERLQTFETGVRYQMYHALALLLTGWLLHQLGASGLSVAGWCFLAGIVLFSGSLYVLVLTDTPWLGAVAPLGGTAFILGWGVLAWSLWQALRP
>NC_015966.1|WP_014067747.1|2592705_2593059_+|hypothetical-protein
MAAFDLNHFTRQLIAEALFYDEEYGALGNLSLVDPREGKERFIASYVPEEGHFTIEEATAWEPGEIDEEVGYALAVDTREYGIYDTPEAAAEALLALAREHDLLPSITLLFEEDEVS
>NC_015966.1|WP_014067756.1|2601438_2602929_+|proline--tRNA-ligase
MADVITPRSVDYAQWYVDVVRAAKLADYSPVRGCMIILPNGYALWENMRAVLDRMFKETGHENAYFPLFIPQSFLAKEAEHVEGFAKECAVVTHSRLKIDEKGQLIPDPESKLEENLIVRPTSETIIWDAFSRWIQSWRDLPILINQWANVVRWEMRTRLFLRTMEFLWQEGHTAHATREEAIEEALRILDIYTTFAEEYMAMPVIQGVKTPSERFAGAVDTYCIEALMQDGRALQAGTSHFLGQNFAKAFDCKFQNQNNELEYVWATSWGVSTRLIGALVMTHSDDQGLVLPPRLAPTQVVIIPIFRNDVEKSAVLEQAGRIERELKDAGFTVKLDARETHRPGWKFNEYEVQGVPVRVAIGPRDVEQGTVELARRDTRTKETVPQEGLAERVRMLLDDIQQNLLARARAFRDEMTTRVDTYEEFKEVLEEKGGFILAHWDGTPETEARIKEETRATIRCIPLDRDAEALGTREEGRDMLTGKPSKQRVVFAKAY
>NC_015966.1|WP_014067757.1|2603049_2605494_+|TonB-dependent-receptor
MVRLFAFLILLFPAAALAQGWGRVAGRVTDAETGAPLAAVTVLVDGTNYGTATDEAGRYQLRLPAGRYVLRFSAIGYATRRDSVTIVRDETTWLDVALAVEVVELEDVTVEARAAETEAGVFTIDPETAQRIPTPLSSGFRALKVLPGVVSNNELSYQYSVRGGGYNENLVFIDGFEVYLPFRAQKGEQEGLGLLNLALAEQVTLYAGGFPARYGGKLSSALEVRYRRPYQEPLRGSATLSLLDAGLAAGSSALDGKIGWMLGVRKARARRFFSTQELKGNYQPDYTDLQGTLTFRPSARHTIELLGIAAHHDFLLDPGTRKTYFGTVSFDPTKPSDLESIWLSYEGEERAGFRTYFGGARLSSWLGTGVRLSHEAAYFETVESESRDVSANAVLYQVDPGSGEHVPEGAARQQDLADNQVRVQTWTAAQRWQFYPHRHAIEAGAYVRHLVFTDRLDELSAAVGADPSGQGLLRVVLDSLNARARLGTWQAGGYVQDAIELLPENRLLVTVGARLDYFDFNGEWTVSPRLSVRYRASDVLTLTGAWGIYYQPPSYQELRGQPNPEQPLRDQLNRNLKAQRAHLVVAGAEYFLPRKRLYLRAEAYWKDLDRLISYEVENVHLEYSGFNDSYGYAYGLDLQVRGEFVPGVESWVNYGFLVTREHFLPAYENDYNRGWRPRPTDQRHTLSLFVQDYVPGDPTWKLHLRILFGSGLPYTPPVPGRRVGTYVAQVPGPRMSARFPEYRRVDMGATKELELTRLPDGRPVYLELSGELLNVFDMTNTVDYTWIPGQNGIWKRIPTRLTPRTFNLRLRVRF
>NC_015966.1|WP_043760916.1|2605556_2606441_-|hypothetical-protein
MSREIAALLLLLSACQLAPSPVVTHWTLTPVWEVTDSLARPESALFDSVANVIYVSNINGGPTEKDGNGYISRIAPDGTLLQARWVTGLHAPKGMARSQGRLYVADIDTLVEIDPVTGQITARYGAPGARFLNDVTADTAGNVYVSDSQTHRIYRLQGDSLTVWLESPLLRSPNGIYALPDYLVVAAADSSAARPGGARYLHAVAYADRTPRPLGAVRPLGGIDGVEPADGGFFLSDWGAARVFFYDPTIDSLQVLVEVSQGTADFDYVPEQQRLYLPVMMSDRLIAYEVRREE
>NC_015966.1|WP_014067759.1|2606522_2607176_-|glycosyltransferase-family-2-protein
MSLPVTAVVVNYQTPELLEVAVRSFRYYYPDVPLLIVDNGSQDHSRRVIEQLLTEGEGTTRALWLPENIYHGPAMHRAMETVSTPYVYFFDSDTETRRGGFLEPMIAALEADPMAYGAGRVVEVDRRRGFRKPGGMPVLTTPHMLLRRDFYFRLPPFIHHGLPTIRNFRAAEQAGYRLISFPIETYVHHLGRGTAARYGYGLGWRARLEYLLHRLGL
>NC_015966.1|WP_014067760.1|2607252_2608281_-|sugar-kinase
MKVVTFGEIMLRLSTPGFTRFVQASSFDVTFGGGEANVAVSLANYGLESYFVTKLPAHEIGQAAVNHLRRFGVRTDFIVRGGDRIGIYFLETGASQRPSKVIYDRAHAAITTLREGEIDWERVLEGASWFHWTGITPALGEGVREELRRALEVARRLGVKVSADLNYRAKLWSVEEAQRVMRSLMEYVDVCIGNEEDAEKSLGIKPKGVDVEAGKLEEAAYRELAQELKRTFGFEAVAITLRESYSASVNGWSALLVDDRDCGEGYRSRRYEIQLVDRVGGGDAFAGGLIYGLLTKEDTREALEFAVAASCLKQTIPGDFNLVSAAEVEKLARGTGSGRVER
>NC_015966.1|WP_014067761.1|2608299_2608944_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MRHEIVSELIRRGAVAVIRMSDPERLVRVVEAICEGGVTAIEITMSVPRAFQMIEEVARRLGDVALVGAGSVLDAETARLVIEAGARYVVSPVFKPEIIQTAHRYDVPALPGAFTPTEILSAHEAGADIVKVFPADVVGMGFFKAIKAPMPQLKLMPTGGVTLTNAGEWLRAGACAVGVGSALLDRAAIAEGRWEKLTENARTLMESIRQARAQ
>NC_015966.1|WP_014067762.1|2608950_2610159_-|D-galactonate-dehydratase-family-protein
MKITDGKVFVCSPGRNFVTLKLYTDEGIYGLGDATLNGREMAVAAYLEEHVIPCLIGRDPFQIEDIWQYLYKGAYWRRGPVTMSAIAAVDMALWDIKGKALNTPVYNLLGGPSRYGVMVYGHASGGDIEEVVDEVGRYLEMGYKAVRAQCGIPGLPTTYGVGRGKLFYEPAEKGLPPEHIWSTEKYLNFVPKLFQRLRDVYGDDVHLLHDVHHRLTPIEAARLGKELEPYHLFWLEDPVPAELQESFRWIRQHTTTPLAVGEVFNSIYDAHLLITEQLIDYLRTSVLRGGGITHMRKVAALAELYHVRTGFHGATDLSPITMAAALHFDLWVPNFGIQEYMRHTPETDEVFPHAYYFQDGYLHPGDAPGLGVDFNEELAARYPYERAYLPVNRKEDGTMFNW
>NC_015966.1|WP_014067763.1|2610185_2611487_-|TRAP-transporter-large-permease
MEWIAVLILVVSFAVLLLLGVPIAVCIGLATILTMLPSIPLAPALTTEAQRIATGLDSFTLLAIPFFILAGHLMNRGGIARRLVSFAEAALGMLPGALAHVNILAAMLFGAISGSAAAVASAIGSIMAPHMEREGYDKGYSVAVNVTSATTGLLIPPSNILIVYSLASGGTSIAALFLAGYVPGLLVGLMLMLVAGWIAWKRRYPVAGRPSLRRLWTTFWDAAPSLLLLVIVIGGIIAGIFTATEAAAVAVLYALILALLYRELRLRDLPRVLLEASSTTAIVLLLIATSMAMSWILAYEQIPQGVSQALLALTDNKILILLIINFVLLAVGTFMDMTPAVLIFTPIFLPVALNLGIDPIHFGIILVLNLCIGLCTPPVGTVLFVGLGVTQTPMTRVLRSLLPMYAAMIIALLLVTYLPELSLWLPRVFGYVE
>NC_015966.1|WP_014067764.1|2611499_2612012_-|TRAP-transporter-small-permease
MERLKQVIDRVLAGLVIVIMAVLVLDVLWQVFTRFVLRDPSSYTEELARFLLIWLGLLGGSYAAGQHLHLAVDLLPGRLQGRQRQILELIIEACTLAFALLLIVGGARLVWLMLYLGQISAALQVPLGYVYVVLPLSGAFIGFYAIYYIWKGVRALRTAGAPVDPQKPAD
>NC_015966.1|WP_155815996.1|2612013_2612991_-|DctP-family-TRAP-transporter-solute-binding-subunit
MLLRAWVPVLLALVLAGCASRSQDVLVLRLAHALGPTHSAHRAMVYLGERLEEKSGGTIRVVVYPSQQLGSERELLELLQIGSLAMAKVSAAVLEGFVPEYQVFSLPYLFRDDTHRFKVLEGPIGQELLLAGERVLLRGLCYYDAGSRSFYTVTRPIYTPDDLRGLKIRTLESPTQIQMVNLMGASATPIPWGEVFTALQQGIVDGAENNPPSFYLSHHYEVARFYTLDEHTSIPDVLLISLHVWNRLTPQQRQWVQEAAMESAQYQKQLWKESTEEALRAVQEAGVEIIYPDKQPFVEKVQPIYEQYRDRPELNRLIARIKAVE

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015966_4	4.14|1340597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1340597-1340631	35	AX059200	Sequence 61 from Patent WO0075335	541-575	0	1.0
NC_015966_4	4.14|1340597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1340597-1340631	35	AX059140	Sequence 1 from Patent WO0075335	8449-8483	0	1.0
NC_015966_4	4.14|1340597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1340597-1340631	35	NC_004735	Rhodothermus phage RM378, complete genome	8449-8483	0	1.0
NC_015966_4	4.15|1340662|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1340662-1340698	37	NC_001755	Rhodothermus marinus R-21 plasmid pRM21, complete sequence	799-835	0	1.0
NC_015966_4	4.22|1341129|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1341129-1341163	35	AX059140	Sequence 1 from Patent WO0075335	101700-101734	0	1.0
NC_015966_4	4.22|1341129|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1341129-1341163	35	NC_004735	Rhodothermus phage RM378, complete genome	101700-101734	0	1.0
NC_015966_4	4.49|1342924|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1342924-1342959	36	AX059140	Sequence 1 from Patent WO0075335	12513-12548	1	0.972
NC_015966_4	4.49|1342924|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1342924-1342959	36	NC_004735	Rhodothermus phage RM378, complete genome	12513-12548	1	0.972
NC_015966_4	4.48|1342857|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1342857-1342893	37	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	298660-298696	8	0.784
NC_015966_4	4.35|1341998|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1341998-1342032	35	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	476599-476633	9	0.743
NC_015966_5	5.12|1443060|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1443060-1443095	36	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	735299-735334	9	0.75
NC_015966_5	5.15|1443258|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1443258-1443293	36	NZ_CP044976	Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence	90342-90377	9	0.75
NC_015966_5	5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1443657-1443694	38	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	354998-355035	9	0.763
NC_015966_5	5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1443657-1443694	38	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1546048-1546085	9	0.763
NC_015966_5	5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1443657-1443694	38	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1665273-1665310	9	0.763
NC_015966_5	5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1443657-1443694	38	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1665219-1665256	9	0.763
NC_015966_5	5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1443657-1443694	38	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	352645-352682	9	0.763
NC_015966_4	4.2|1339789|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT	1339789-1339825	37	NC_014035	Rhodobacter capsulatus SB 1003 plasmid pRCB133, complete sequence	124128-124164	10	0.73

1. spacer 4.14|1340597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to AX059200 (Sequence 61 from Patent WO0075335) position: , mismatch: 0, identity: 1.0

ctccgaaagaagttacttcctcagtacaaagagca	CRISPR spacer
ctccgaaagaagttacttcctcagtacaaagagca	Protospacer
***********************************

2. spacer 4.14|1340597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to AX059140 (Sequence 1 from Patent WO0075335) position: , mismatch: 0, identity: 1.0

ctccgaaagaagttacttcctcagtacaaagagca	CRISPR spacer
ctccgaaagaagttacttcctcagtacaaagagca	Protospacer
***********************************

3. spacer 4.14|1340597|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NC_004735 (Rhodothermus phage RM378, complete genome) position: , mismatch: 0, identity: 1.0

ctccgaaagaagttacttcctcagtacaaagagca	CRISPR spacer
ctccgaaagaagttacttcctcagtacaaagagca	Protospacer
***********************************

4. spacer 4.15|1340662|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NC_001755 (Rhodothermus marinus R-21 plasmid pRM21, complete sequence) position: , mismatch: 0, identity: 1.0

ctggccctcgatctgtacgcttggctttcgtatcggg	CRISPR spacer
ctggccctcgatctgtacgcttggctttcgtatcggg	Protospacer
*************************************

5. spacer 4.22|1341129|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to AX059140 (Sequence 1 from Patent WO0075335) position: , mismatch: 0, identity: 1.0

gcggtaattacatctggatcgataatggcttttac	CRISPR spacer
gcggtaattacatctggatcgataatggcttttac	Protospacer
***********************************

6. spacer 4.22|1341129|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NC_004735 (Rhodothermus phage RM378, complete genome) position: , mismatch: 0, identity: 1.0

gcggtaattacatctggatcgataatggcttttac	CRISPR spacer
gcggtaattacatctggatcgataatggcttttac	Protospacer
***********************************

7. spacer 4.49|1342924|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to AX059140 (Sequence 1 from Patent WO0075335) position: , mismatch: 1, identity: 0.972

atcaggtggaggattcgatcgaggggtggtgctcgg	CRISPR spacer
atcaggtggaggattcgatcgagggatggtgctcgg	Protospacer
*************************.**********

8. spacer 4.49|1342924|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NC_004735 (Rhodothermus phage RM378, complete genome) position: , mismatch: 1, identity: 0.972

atcaggtggaggattcgatcgaggggtggtgctcgg	CRISPR spacer
atcaggtggaggattcgatcgagggatggtgctcgg	Protospacer
*************************.**********

9. spacer 4.48|1342857|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.784

agctgctttgcagcagctaggacgatggacgacacaa-	CRISPR spacer
cgctgctttgcagcagccaggacgct-gacgacgggca	Protospacer
 ****************.****** * ******. .  

10. spacer 4.35|1341998|35|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 9, identity: 0.743

accgcccgcgcgtggcgatcaggtgctcggcctcc	CRISPR spacer
gcaaagccggcgtggcgatcaggtgctccacctcc	Protospacer
.* .  *  ******************* .*****

11. spacer 5.12|1443060|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 9, identity: 0.75

gaaagcggccgccgggccgcccttgcttttcccagt-----	CRISPR spacer
gaaaccggccgccgggccgcacttg-----ccaagctgctg	Protospacer
**** *************** ****     ** **.     

12. spacer 5.15|1443258|36|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044976 (Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence) position: , mismatch: 9, identity: 0.75

gtctgattgtcgtggactatctgcaactgctccttc	CRISPR spacer
ggctgatcgtcgtggactatctgcagctgatgaccg	Protospacer
* *****.*****************.*** *  .. 

13. spacer 5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.763

tccggcggcaatcacgccgtccacatcgaac-ccgccgc	CRISPR spacer
cggcgcggcaatcacgccgcccacaccgaacagcgcct-	Protospacer
.   ***************.*****.*****  ****  

14. spacer 5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.763

tccggcggcaatcacgccgtccacatcgaac-ccgccgc	CRISPR spacer
cggcgcggcaatcacgccgcccacaccgaacagcgcct-	Protospacer
.   ***************.*****.*****  ****  

15. spacer 5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.763

tccggcggcaatcacgccgtccacatcgaac-ccgccgc	CRISPR spacer
cggcgcggcaatcacgccgcccacaccgaacagcgcct-	Protospacer
.   ***************.*****.*****  ****  

16. spacer 5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.763

tccggcggcaatcacgccgtccacatcgaac-ccgccgc	CRISPR spacer
cggcgcggcaatcacgccgcccacaccgaacagcgcct-	Protospacer
.   ***************.*****.*****  ****  

17. spacer 5.21|1443657|38|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.763

tccggcggcaatcacgccgtccacatcgaac-ccgccgc	CRISPR spacer
cggcgcggcaatcacgccgcccacaccgaacagcgcct-	Protospacer
.   ***************.*****.*****  ****  

18. spacer 4.2|1339789|37|NC_015966|PILER-CR,CRISPRCasFinder,CRT matches to NC_014035 (Rhodobacter capsulatus SB 1003 plasmid pRCB133, complete sequence) position: , mismatch: 10, identity: 0.73

ttgacaatgccgatgtgggcgcgctggcctacatcag	CRISPR spacer
ctcagctggccgatgtgggcgcgctggccaatatcca	Protospacer
.* *    ********************* *.*** .