CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017619	Streptococcus suis SS12, complete sequence	2 crisprs	PrimPol,DinG,csa3,cas3,DEDDh	0	0	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017619_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017619_1

46406-46525

Orphan

Consensus_repeat	Method
TTAGATTGGTCGAGTTCTGTCCCACTCCCAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017619_1

>merge|NC_017619|1|46406-46525|CRISPRCasFinder
TTAGATTGGTCGAGTTCTGTCCCACTCCCAAACGTTTCACGCTCCAAATCTGACCTAATCAACTGTGCGGGGTGGGAAGACGAACTCCTTAGATTGGTCGAGTTCTGTCCCACTCCCAAA

>NC_017619|1|1|46406-46525|CRISPRCasFinder
TTAGATTGGTCGAGTTCTGTCCCACTCCCAAA	CGTTTCACGCTCCAAATCTGACCTAATCAACTGTGCGGGGTGGGAAGACGAACTCC
TTAGATTGGTCGAGTTCTGTCCCACTCCCAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017619.1\|WP_011921656.1\|42809_43571_+\|hypothetical-protein	unknown	unknown	unknown
NC_017619.1\|WP_011922533.1\|37689_38241_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|235544
NC_017619.1\|WP_011921670.1\|53877_54624_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|378940
NC_017619.1\|WP_011921653.1\|39923_41186_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NC_017619.1\|WP_012774888.1\|55507_56407_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|376134
NC_017619.1\|WP_011921662.1\|47926_48505_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_017619.1\|WP_014636540.1\|47188_47917_+\|hypothetical-protein	unknown	unknown	unknown
NC_017619.1\|WP_012774883.1\|41686_42766_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NC_017619.1\|WP_011921659.1\|44871_46164_+\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|176464
NC_017619.1\|WP_014636188.1\|48519_48948_+\|hypothetical-protein	unknown	unknown	unknown
NC_017619.1\|WP_012774887.1\|50594_52307_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_017619.1\|WP_011921652.1\|38250_39798_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NC_017619.1\|WP_012774882.1\|36670_37693_+\|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl\|CDD\|235439
NC_017619.1\|WP_011921654.1\|41211_41700_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|223119
NC_017619.1\|WP_011921671.1\|54625_55261_+\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|319825
NC_017619.1\|WP_012775420.1\|49818_50592_+\|membrane-protein	unknown	unknown	unknown
NC_017619.1\|WP_014636539.1\|35160_36615_+\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235984
NC_017619.1\|WP_004195448.1\|52876_53878_+\|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl\|CDD\|234619
NC_017619.1\|WP_011921665.1\|48940_49813_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_017619.1\|WP_011922536.1\|43643_44870_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017619.1\|WP_011922533.1\|37689_38241_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|235544	PRK05647, purN, phosphoribosylglycinamide formyltransferase; Reviewed.	3.41268e-103
NC_017619.1\|WP_012774887.1\|50594_52307_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	7.64841e-130
NC_017619.1\|WP_011921670.1\|53877_54624_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|378940	pfam12746, GNAT_acetyltran, GNAT acetyltransferase. Many of the members are annotated s being Zwittermicin A resistance proteins, whereas others are listed as being GNAT acetyltransferases. The family has similarities to the GNAT acetyltransferase family.	3.03789e-125
NC_017619.1\|WP_011921653.1\|39923_41186_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NC_017619.1\|WP_012774888.1\|55507_56407_+\|transcriptional-regulator	gnl\|CDD\|376134	pfam18710, ComR_TPR, ComR tetratricopeptide. In Gram-positive bacteria, cell-to-cell communication mainly relies on extracellular signaling peptides. ComR is a member of the RNPP family, which positively controls competence for natural DNA transformation in streptococci. It is directly activated by the binding of its associated pheromone XIP. The crystal structure analysis of ComR shows that it contains an N-terminal helix-turn-helix (HTH), DNA binding domain (DBD) and a C-terminal tetratricopeptide repeat (TPR) domain. The TPR domain is composed of 11 alpha-helices forming 5 TPR motifs followed by an additional C-terminal alpha-helix 16 called CAP. The pheromone XIP binding site is found in the TPR region. Biochemical and mutational analysis indicate that, if the interacting XIP is accepted it can then trigger the conformational change of the TPR domain to open the DBD-TPR interface to allow dimer formation that is required to bind DNA.	1.45483e-88
NC_017619.1\|WP_011921662.1\|47926_48505_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.10858e-06
NC_017619.1\|WP_012774883.1\|41686_42766_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	0
NC_017619.1\|WP_011921659.1\|44871_46164_+\|adenylosuccinate-lyase	gnl\|CDD\|176464	cd01360, Adenylsuccinate_lyase_1, Adenylsuccinate lyase (ASL)_subgroup 1. This subgroup contains bacterial and archeal proteins similar to ASL, a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASL catalyzes two steps in the de novo purine biosynthesis: the conversion of 5-aminoimidazole-(N-succinylocarboxamide) ribotide (SAICAR) into 5-aminoimidazole-4-carboxamide ribotide (AICAR) and, the conversion of adenylsuccinate (SAMP) into adenosine monophosphate (AMP).	0
NC_017619.1\|WP_011921652.1\|38250_39798_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_017619.1\|WP_012774882.1\|36670_37693_+\|phosphoribosylformylglycinamidine-cyclo-ligase	gnl\|CDD\|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NC_017619.1\|WP_011921654.1\|41211_41700_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	7.53457e-85
NC_017619.1\|WP_011921671.1\|54625_55261_+\|HAD-IA-family-hydrolase	gnl\|CDD\|319825	cd07523, HAD_YsbA-like, uncharacterized family of the haloacid dehalogenase-like superfamily, similar to the uncharacterized Lactococcus lactis YsbA. The specific function of Lactococcus lactis YsbA is unknown. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.06481e-63
NC_017619.1\|WP_014636539.1\|35160_36615_+\|amidophosphoribosyltransferase	gnl\|CDD\|235984	PRK07272, PRK07272, amidophosphoribosyltransferase; Provisional.	0
NC_017619.1\|WP_004195448.1\|52876_53878_+\|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl\|CDD\|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0
NC_017619.1\|WP_011921665.1\|48940_49813_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	9.50697e-73

>NC_017619.1|WP_011921659.1|44871_46164_+|adenylosuccinate-lyase
MIERYSRPEMAAIWSEENKYEAWLEVEILADEAWAELGEIPKEDVALIREKATFDIDRILEIEEETRHDVVAFTRAVSESLGEERKWVHYGLTSTDVVDTAYGYLYKQANDIIRRDLENFTTIIADKAREHKYTIMMGRTHGVHAEPTTFGLKLATWYSEMKRNMERFDVAAKGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDLHAEYFSALALIATSIERMATEIRGLQKSEQREVEEYFAKGQKGSSAMPHKRNPIGSENMTGLARVVRGHLVTAFENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNLTVFPENMKRNMESTFGLIYSQRVMLSLIEKGMTREEAYDLVQPKTAQSWDNQVDFKPLLEADERVTAKLSQEEIDELFNPDYYAKRVDDIFERLGL
>NC_017619.1|WP_011922536.1|43643_44870_+|hypothetical-protein
MLNKEWYFKNFNMVSELDISGEFIYTGISIVNNMDRIAPEMPTELFLALYNISVGVERLQKIILVLWEFDEVDSIEDFSESLKIHNQVELHSRIEKAINKKIFSKQECQFLELLKEFYSNARYDRFSAVGNRWEYELISKFFSNNQISYEESVSDSQVILINDSIRKLIGRVLSRIVKNYYLLVEEGSNKSGTYSYELRNDSKAQKIFLHMENRRGLSSIKIDERIALSEILIYLRNTSDKSSYLKFIEGIYPLDFDKMEISRYLSIILLEDRIPQDLIDEIEYIYAEKDIKVGERIENLDLLTKNNMQVTFDYPYLKEVYIILEEVKKQESINDDTISRLEESNCYIDDSDTQEIIESIIAVARQYRNNKILKEEFIKEFSSHYKTLEDNYTLSYISNLMQLEVRSK
>NC_017619.1|WP_011921656.1|42809_43571_+|hypothetical-protein
MPLPQKIQEEIKRYCNNHLPNNDWYEKEFDFIHDVSLKNRIIREFKSIRYAYKLYEGITAEEEHLIFEIRSQILAYASIYEAVVEYVLETYYSDTQVYDDLVHQNNVMTKIDIPEEKRKKLERELIHLVDNGTKNIEIHTFFYQRKRKASTSIRFDAKCRAAEELNIISKIYQKGNKVVADLPSDIIEIYEYRNAIHLIAEQRKNIDYELELSQRAYRRMKPFIEQIKDRLITDNKLIIKNTKDTLTDSSIKN
>NC_017619.1|WP_012774883.1|41686_42766_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MTSSKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASKVSEVIVAPYHDVAALKQLAERCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNRIFEKDFLAKKAGVQVAPYKVVTSSLDLEGLDLSKNYVLKTATGGYDGHGQKVIREEADLVEASQLANSAECVLEEFVNFDLEISVLVSGNGSDYTVFPVQENIHRNNILYKTIVPARIFDELAEKAKTMALQIADKLHLVGTLCVEMFVAGQEILVNEIAPRPHNSGHYSIEACDFSQFDTHIRGILGEPLPPIRLLSPAVMINVLGQDMETVQTFLQENPTAHPHFYGKLEAKHNRKMGHVTVLGEDAESVEEFEN
>NC_017619.1|WP_011921654.1|41211_41700_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MNIPISIIMGSSSDWKTMKKAADMLDKFGVAYEKKVVSAHRTPDLMFRHAEEARGHGFKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVQSRALSGVDSLYSIVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQTIAAQLADFAKEQEKIAEAMTDDLI
>NC_017619.1|WP_011921653.1|39923_41186_+|phosphoribosylamine--glycine-ligase
MKLLVVGSGGREHAIAKKLLESEQVEQVFVAPGNDGMTLDGIELVNIGISEHSAIINFAKENDVAWTFVGPDDALAAGIVDDFEQAGLKAFGPSRLAAELEWSKDFAKQIMVKYGIPTAAFGTFSNFEEAKAYIEEQGAPIVVKADGLALGKGVVVAETVEQAVEAAREMLLDNKFGDSGARVVIEEFLAGEEFSLFALVNGDQFYILPTAQDHKRAFDGDQGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPILEGMIADGRSYLGVLYAGLILTDQGPKVIEFNARFGDPETQIILPRLTSDFAQNIDDILHKRPTQLTWLDSGVTLGVVVASNGYPLDYEKGVELPAKTEGDITTYYAGARFAENSRALLSNGGRVYMLVTTADTVQDAQEKIYSELKNQDTTGLFYRTDIGSKAVK
>NC_017619.1|WP_011921652.1|38250_39798_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MTKRALISVSDKNGIVEFAQELTKLGWEIISTGGTKVALDNAGVATIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDVDSHLQAAKDHEIGLIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYPTVLGEIAEQGQTTYPTRQRLAAKVFRHTAAYDALIADYFTKQVGEDKPEKLTITYDLNQPMRYGENPQQNADFYQNALPTDYSIAAAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHMNPCGIGQAETIEKAWDYAYEADPVSIFGGIVVLNREVDAATAEKMHPIFLEIIIAPSYSAEALAILTNKKKNLRILELAFDAQDASEVEKEFTGVVGGLLVQDQDVVVESPADWQVVTERQPSEQEWAAMEFAWKSSKYVKSNGIIITNDKMTLGVGPGQTNRVASVRIAIEQAKDRLEGAVLASDAFFPFADNVEEIAAAGIKAIIQPGGSVRDQDSIDMANKYGLTMVFTGVRHFRH
>NC_017619.1|WP_011922533.1|37689_38241_+|phosphoribosylglycinamide-formyltransferase
MKRIAVFASGNGSNFQVIAEQFEVAFVFSDRRNAYVLERAEKLGVPTFAFELKEFADKQAYEEAIIQLLDQHQIDLVVLAGYMKIVGPTLLAQYEGRIINIHPAYLPEFPGAHGIEDAWNAGVAESGVTVHWVDSGIDTGQIIKQVRVPRLADDILETFEARIHEAEYQLYPAVLEELGAVKK
>NC_017619.1|WP_012774882.1|36670_37693_+|phosphoribosylformylglycinamidine-cyclo-ligase
MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERLGVMGALGGFGGMFDLTKLDVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYIATGKNEPAKLEQVVAGVAEGCVQAGCGLIGGETAEMPGMYGEDDYDLAGFAVGIAEKSQIIDGSKVQEGDILLGLASSGIHSNGYSLVRRVFADVSGDALLPELNGRALKDVLLEPTRIYVQQVLPLVKAGLVNGIAHITGGGFIENVPRMFADNLAAEIEEDKIPVLPIFTALETYGQIKHEEMFEIFNMGIGMVLAVSPGKVEKVRELVGEEVYEIGRIITKEDKSVVIK
>NC_017619.1|WP_014636539.1|35160_36615_+|amidophosphoribosyltransferase
MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGILANDGGQLCRHRGTGLIAEVFKNPADLEALTGTAAIGHVRYATSGSASINNIQPFLFDFADMQVGLAHNGNLTNAVSLKAELEKNGSIFSSSSDTEILMHLIRRSHNPDFMGKIKEALNTVKGGFAYLIMLEEKLVAALDPNGFRPLSIGKMKNGAWVVASETCAFEVVGAEWVRDVEPGEIVVIDDSGIQYDSYTRDTQLAVCSMEYVYFARPDSVIHGVNVHTARKNMGRRLAQEFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELREQGVRMKLSAVSSVVKGKRVVMIDDSIVRGTTSRRIVQLLRDAGAKEVHVAIGSPELKYPCFYGIDIQTRRELISANHTVEEVCEIIGADSLTYLSLEGMIEAIGIETDAPKGGLCVAYFDGEFPTPLYDYEEEYLRSLEEKTSFYIENVK
>NC_017619.1|WP_014636540.1|47188_47917_+|hypothetical-protein
MNMFRSIFKSVIHRRDVALFYAFAGLPILVPILSKFLVGVKAEYTDNFLDFLGAALATQDGIVLPVLLLSLIISAVFRDEIDSGILFLYKDLNRTRLFNAKIISLVVMYASYVLLTVLTSAIAYFGFLNASGKVVSDDWSNVQSTFLSIFATISINVIGILLVSTVSIKAKSLQAVLAGVFWSLFTTTAPLLIGVRYVVPNGYAKMSLDQPLLAWSLVVVITTFYTVATYLKGRSNFEKLEF
>NC_017619.1|WP_011921662.1|47926_48505_+|CPBP-family-intramembrane-metalloprotease
MVVRYMRPVALSLALIVLASISYLLATSLVLFSSSQFLQLAYLFSIMVGMPIGFILLPSMITKRYQLCQELSEVKFSWKSFVLLAIAIFLVNFWFIQSDEYVNQFIIATCEEFLFRYLIYRILKSEYPTWLAMLVTSLLFGVLLHMNYSLLDNLIIRTPLGLLFSVLATRFGLQYAIGGHWIYNLLVSRFPF
>NC_017619.1|WP_014636188.1|48519_48948_+|hypothetical-protein
MIFILLLSLFYICLTVASSQLLLSLSVPVLLLLTYLLPPIVNSICMGLQKDKSWKAWSAGIFPTMSMIFYAAFAYITSSNGQWEQFAQLHTVSDDVMSVELAGELLVPSQMLFVAVLYYGTAIATYFIQQAGRKKEKGATYA
>NC_017619.1|WP_011921665.1|48940_49813_+|ABC-transporter-ATP-binding-protein
MLKINHLSKQFAGNEFYSLKDVSLEINKGEIVGLIGKNGAGKSTLMKLMAKSLKPSSGTITYKGTDIFSQDNLLADFGIMIDPVFYPEMTVMDNLKFYLDLHGKKDLYPNIEKTLKLVELWDARNRKPKGFSFGMKQRTALAIALVAEPDFLILDEPFVGLDPIGVQKLIDILKQWSSERQISMLISSHQLGELEALCSRYVYIESGELADAFEGKSHPSVLVQLDTTKNLDSVKDLLNDHVVLEGEVLEISTATPTSELNQIFGVLTRQELIVKLEVKENHLKEIFTKG
>NC_017619.1|WP_012775420.1|49818_50592_+|membrane-protein
MKQIFPAVFRTIWKRKETQVYLLFTLFPFIYLVTSFIEGSNFMQIHAGEGYKVSLVAFTNMMVSSADSFILPSLTLYFLAISVFRKEVDEHTMFLYRDLGRKQIFWSKYLGLLATIVIFYGLFFVTSAFVHYVRVIHLPFGSPAVFEASLAESLSNVFCIVAYLLKDILSISLATALCLYLKNITTMITGFLVTITMMILAIVGGPVAMLFPTSYMTLASEGLTGAGLAYLGAICVTIIYVLVFTKIAAKKFKNLEF
>NC_017619.1|WP_012774887.1|50594_52307_+|ABC-transporter-ATP-binding-protein
MNKRLVGVLLKSLNKTMFLFGIVLSALGVGMGLFLPQFIGKLLDQTYLSNLLTRPELLAGFILFFVSVYAVQALSNYFIGRSGSNALKQLQQYIYESLLTTSVKDLDQYQSGDLASRLTNDMSVVLNFITVILPNFLMNGLMVMGSIYFLWTISPWLTGLSLFLLPLLSMVMIPMNQRLEGYYSAYQEGLGQVSSRISHKFTTIRLMKAFQGEKHEQREMGKSFQYLSQTFEKMIGLSAVQHTLVSSLMTGFIILMLLIAGIEVTKGVMTMATLTTFVLYMMQLIDPVTDIAASLNELTEFHAVSKRLVELLELNKEEQVDTELVDATSIQLEKVRFSYHTDPILNGVSVRIPEGAHVAIVGPSGAGKSTIFALLMKYYQDYKGKIRIGQQCLSDISTKEMRRLISFIPQDNTLFHGTIRENLLYGKNESVSEERIAYILKELGLSPLVAELEDGLDTRISENGTGLSEGQKQRFSIARALLLEHPIYLLDEATASLDTVTERVISKAIDRLTAGKTRLTIAHRLHTVREADAILVLDKNGQVADYGHHQQLVERNHLYQDFLRGLPQAS
>NC_017619.1|WP_004195448.1|52876_53878_+|Holliday-junction-branch-migration-DNA-helicase-RuvB
MTNRILDMEQMQDEEYVERTLRPQKLNEYIGQDKVKDQLKIFIEAAKLRDEALDHTLLFGPPGLGKTTMAFVIANELGVNIKQTSGPVIEKAGDLVALLNDLEPGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGEASRSVHLELPPFTLIGATTRAGMLSNPLRARFGITGHMEYYELADLTEIVERTADIFDMEITHEAAIELARRSRGTPRIANRLLKRVRDFAQIMGDGLIDDSITDKALTMLDVDREGLDYVDQKILRTMIEMYGGGPVGLNTLSVNIAEERETVEDMYEPYLIQQGFLMRTRTGRVATAKAYEHLGYPYTEK
>NC_017619.1|WP_011921670.1|53877_54624_+|GNAT-family-N-acetyltransferase
MAEQMRQAARLFGDWPETIIWTCLEGVMGDIYVDDSQLPQSALALYGRQSFFGFLAGQPHRDLLKICEGKDMILVPQNQNWSDLIEGTYGDGIRSFTRYATKKDTEFDLGHLQKLVDDLPESFDMKRIDRNLYEACLVEEWSRDLVGNYIDVEQFLDLGLGYVILHKGQVVSGASSYASYSAGIEIEVDTREDYRGLGLAKACAAQLILACLDRGLYPSWDAHTLTSLKLAEKLGYQLDKPYQAYEWR
>NC_017619.1|WP_011921671.1|54625_55261_+|HAD-IA-family-hydrolase
MTPTFIWDLDGTLLDSYEAILAGIQETYQEYVLPFDRAEVRKFILRYSVKDLLVRDADKYGLDSDELNRVRATSLKEKNTQIPLMAGAVEILNWTAEQGIQNFVYTHKSDNAFQVLEDLGVRHHFTEILTSDSGFARKPSPEALLFLIEKYGLDKENTYYIGDRLLDVETAVNAGIHSINLQIDGVEQNWKIVSLLDIKQILTDKSSHNNL
>NC_017619.1|WP_012774888.1|55507_56407_+|transcriptional-regulator
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLKFDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELNDLLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQSTQDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

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Crispr_ID: NC_017619_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017619_2

1788632-1788755

Orphan

Consensus_repeat	Method
CCAATCAACCACTACTGCGCTAAGATGTTGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017619_2

>merge|NC_017619|2|1788632-1788755|CRISPRCasFinder
CCAATCAACCACTACTGCGCTAAGATGTTGACACTAACGTTGAGAAGCGGTACAGGGCTTGAGCCCAGCTTCACTCCACTGGACTGTTAAACCCAATCAACCACTACTGCGCTGAGATGTTGAC

>NC_017619|2|2|1788632-1788755|CRISPRCasFinder
CCAATCAACCACTACTGCGCTAAGATGTTGAC	ACTAACGTTGAGAAGCGGTACAGGGCTTGAGCCCAGCTTCACTCCACTGGACTGTTAAAC
CCAATCAACCACTACTGCGCTGAGATGTTGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017619.1\|WP_012028491.1\|1791910_1793476_+\|ABC-transporter-substrate-binding-protein/permease	unknown	unknown	gnl\|CDD\|270345
NC_017619.1\|WP_012027774.1\|1794632_1795535_-\|SPFH-domain-containing-protein	unknown	unknown	gnl\|CDD\|259805
NC_017619.1\|WP_012027769.1\|1788928_1790101_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463
NC_017619.1\|WP_009910805.1\|1798240_1798717_-\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183365
NC_017619.1\|WP_012027759.1\|1777088_1778030_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048
NC_017619.1\|WP_012775334.1\|1790097_1790820_-\|adaptor-protein-MecA	unknown	unknown	gnl\|CDD\|235030
NC_017619.1\|WP_009910800.1\|1794337_1794547_-\|hypothetical-protein	unknown	unknown	unknown
NC_017619.1\|WP_012027765.1\|1784669_1785110_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_017619.1\|WP_012027766.1\|1785096_1786320_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_017619.1\|WP_002937416.1\|1795544_1796795_-\|threonine-ammonia-lyase-IlvA	unknown	unknown	gnl\|CDD\|236318
NC_017619.1\|WP_002938165.1\|1787602_1788376_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NC_017619.1\|WP_002938151.1\|1782904_1784320_-\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NC_017619.1\|WP_002942324.1\|1778032_1779031_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NC_017619.1\|WP_002938143.1\|1776130_1777087_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_017619.1\|WP_009910803.1\|1797077_1798100_-\|ketol-acid-reductoisomerase	unknown	unknown	gnl\|CDD\|235491
NC_017619.1\|WP_012027770.1\|1790947_1791784_-\|undecaprenyl-diphosphate-phosphatase	unknown	unknown	gnl\|CDD\|234712
NC_017619.1\|WP_012775331.1\|1779407_1781198_-\|oligopeptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173875
NC_017619.1\|WP_012775332.1\|1781410_1782652_+\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NC_017619.1\|WP_012775335.1\|1793468_1794212_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_017619.1\|WP_012775333.1\|1786323_1787586_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791

Protein	Function_ID	Function_description	E-value
NC_017619.1\|WP_012028491.1\|1791910_1793476_+\|ABC-transporter-substrate-binding-protein/permease	gnl\|CDD\|270345	cd13627, PBP2_AA_binding_like_2, Substrate-binding domain of putative amino acid-binding protein; the type 2 periplasmic-binding protein fold. This putative amino acid-binding protein belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.18368e-91
NC_017619.1\|WP_012027774.1\|1794632_1795535_-\|SPFH-domain-containing-protein	gnl\|CDD\|259805	cd03407, SPFH_like_u4, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease and, in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	3.71678e-128
NC_017619.1\|WP_012027769.1\|1788928_1790101_-\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	9.66017e-81
NC_017619.1\|WP_009910805.1\|1798240_1798717_-\|acetolactate-synthase-small-subunit	gnl\|CDD\|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	1.6123e-73
NC_017619.1\|WP_012027759.1\|1777088_1778030_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	2.10004e-119
NC_017619.1\|WP_012775334.1\|1790097_1790820_-\|adaptor-protein-MecA	gnl\|CDD\|235030	PRK02315, PRK02315, adaptor protein MecA.	2.58092e-83
NC_017619.1\|WP_009910803.1\|1797077_1798100_-\|ketol-acid-reductoisomerase	gnl\|CDD\|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
NC_017619.1\|WP_012027765.1\|1784669_1785110_-\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	8.16406e-68
NC_017619.1\|WP_012027766.1\|1785096_1786320_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_017619.1\|WP_002937416.1\|1795544_1796795_-\|threonine-ammonia-lyase-IlvA	gnl\|CDD\|236318	PRK08639, PRK08639, threonine dehydratase; Validated.	0
NC_017619.1\|WP_002938165.1\|1787602_1788376_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	2.74827e-148
NC_017619.1\|WP_002938151.1\|1782904_1784320_-\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_017619.1\|WP_002942324.1\|1778032_1779031_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.71068e-159
NC_017619.1\|WP_002938143.1\|1776130_1777087_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.06681e-112
NC_017619.1\|WP_012027770.1\|1790947_1791784_-\|undecaprenyl-diphosphate-phosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	1.49616e-101
NC_017619.1\|WP_012775331.1\|1779407_1781198_-\|oligopeptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173875	cd08510, PBP2_Lactococcal_OppA_like, The substrate binding component of an ABC-type lactococcal OppA-like transport system contains. This family represents the substrate binding domain of an ATP-binding cassette (ABC)-type oligopeptide import system from Lactococcus lactis and other gram-positive bacteria, as well as its closet homologs from gram-negative bacteria. Oligopeptide-binding protein (OppA) from Lactococcus lactis can bind peptides of length from 4 to at least 35 residues without sequence preference. The oligopeptide import system OppABCDEF is consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and also is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_017619.1\|WP_012775332.1\|1781410_1782652_+\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	5.36323e-91
NC_017619.1\|WP_012775335.1\|1793468_1794212_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	7.30548e-147
NC_017619.1\|WP_012775333.1\|1786323_1787586_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	4.97321e-124

>NC_017619.1|WP_002938165.1|1787602_1788376_-|Fe-S-cluster-assembly-ATPase-SufC
MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKSTLSAAIMGNPSYEVTQGEILFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLRAAMNAGKEDEDKISVRDFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPTFALLDEIDSGLDIDALKVVSKGINAMRGEGFGAMIITHYQRLLNYITPDVVHVMMEGRVVLSGGPELAQRLEKEGYVQVAAELGIDYKEDDI
>NC_017619.1|WP_012775333.1|1786323_1787586_-|Fe-S-cluster-assembly-protein-SufD
MTKEKIQEFSALQAEPTWLTDLRLKAFDKIAELDLPVIERVKFHRWNLGDGSLATNDEIGAVPDFTAIGDNPMLVQVGSQTILEQLPVALVEKGVVFTDFASAMDVIPDVLEKYLGAAVAYDEHKLAAYNTAYFNATAVLYVPDNVEIDQPVEALFYQDSTSPVAFNKRVLIIAGKNAKLNYLERFESLGDGAATTSANIVVEVIALAGSQIKFAAIDRLGKHLDTYLNRRGYLGNDATIDWAIGLLNEGNVVADLDSELKGNGSHANLKVVGLSSGRQVQGVDTRVTNYGHNSVGHILQHGVILESGTLTFNGIGHIVRGAKGADAQQESRVLMLSDKARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDRATAERLVVRGFLGSVITEIPVKEVRDQLIAVIEEKLTKR
>NC_017619.1|WP_012027766.1|1785096_1786320_-|cysteine-desulfurase
MDLERIRKEFSILDQVVNDEPLVYLDNAATTQKPQQVLDVLADYYQKDNANVHRGVHTLSERATTRYEAARQKVADFIQAKSSKEILFTRGTTTSLNWVAQFAKEILQPDQEVIISVQEHHSNIIPWQQACQQTGAKLRYVTLKDGELDMDHLRSLLSSKTKFVSLAHVSNVLGGVVPIGEIAELVHQVGAYLVVDGAQSVPHMGVNVQELDVDFYAFSGHKMLGPTGIGILYGKEELLNLMSPVEFGGEMIDFVYEQSATWKELPWKFEAGTPNIAGAIGLGAAIDYLTEIGMDAIQAHEAELVDYVFPKLQAIPGLTIYGSQDLSKRTGVIAFNLDDLHPHDVATALDYEGVAVRAGHHCAQPLLRYLQVPATVRASFYIYNTKADCDKLVEAIIKTKEFFNGPI
>NC_017619.1|WP_012027765.1|1784669_1785110_-|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MALSRLDSLYMAVVSEHSKSPRHRGSLDGVEKLELHNPTCGDVIELSVKIEKDVITDIAFDGVGCTISTASASMMTEAVLGKEISQIQELAEIFSQMVRGQEDPRQKELGDASLLAGVAKFPQRIKCATLPWNALKKALSLRSSAE
>NC_017619.1|WP_002938151.1|1782904_1784320_-|Fe-S-cluster-assembly-protein-SufB
MSEERIEPTPIDLGEYKFGFHDENVELVASTGKGLNEEVIREMSRIKGEPEWMLEFRLKSYETFKKMPMQTWGADLSELDFDDIVYYQKPSDKPARSWDDVPDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEYDKHGIIFTDTDTALKEHPELFKKYFGKLVPPSDNKLAALNSAVWSGGTFIYVPKGVKLDIPLQTYFRINNEGTGQFERTLIIVDEGASVHYVEGCTAPTYSTASLHAAIVEIIAHEGAYMRYTTIQNWSDNVYNLVTKRARAEKNATVEWIDGNLGAKTTMKYPAVYLEGEGARGTMLSIAFANKGQVQDTGAKMIHNAPRTSSSIVSKSIARGGGEVNYRGQVTFAKNSAKSISHIECDTIIMDDISKSDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLIAYEMEGSVG
>NC_017619.1|WP_012775332.1|1781410_1782652_+|D-alanyl-D-alanine-carboxypeptidase
MRKLLLTLTTILAVFLTSTPILAEDFSVAAKHAIAVEVSSGKILYEQDAETKASIASISKTLSIYLVYEALAKGEITLDTMVDISDYPYSLTSNTELSNVNLDERSYSVRDLLNASLITSSNSAIIALAEKIAGSEAAFVDRMKAKVQEWGITDTKIVNVSGLDNTDLGENIYPGSSPEDVNMFSALDVAIIARRLILDYPQVLDITSLNAYDFGGYTYYSTNQMLSDGTHARGGVDGLKTGTSNSAGSSFLATTQQAGMRIITVVLNANDGLTSPENRFVATNDLMNYVYSNFSLVTLVKKSEAFGDSKIKVFNGEKETSPVVAAADLTVVQRNQTDNVPTATFTTDIKEIDAPLKAGTLVSKLQLKDQDLIGKGYISEQTGVDMIIPSDMKEASWPFSWWNQFVRYVNEKL
>NC_017619.1|WP_012775331.1|1779407_1781198_-|oligopeptide-ABC-transporter-substrate-binding-protein
MKKTTKLFALAGVTLLSASVLAACGSKQSGAAKQELSFPAEVKQDGTAVADAQLKYAWVSPTTSSGLLIDELTENTTDSTFGGMVDISMFGYDGERKLDDSGLAKAEFDVKGKKITVSLTGKDYKWSDGESFTINDYIFTIKSMASKDYTGIRFDDKFLNIEGMQEFVDGKASDISGIKKVDDYTVELTVKEMSPSMMYAGGDVPAYIQPEHIYKDIPVADWEKSEYSRTAKLVGMGPWKIKEIVNGESITYVPNEYFFKGTKPKTSSLKIDIVSPDTIVSEMKAGNYDIAEMPVDQLDSYKDASNLNIVGQLESSYEYISFNFGKYDEAAGKNVMDENAKMNDVKLRQAIAYAIDTKTAGKSLYNGLYHPAKSLIISFFGDIHDSELEGYSYNPEKAKKLLDEAGYKDVDGDGIREGKDGKAFKITFAARKRTEANEALVQQYIAWWKEVGLNVELYTGRTVEGKSFYNSVQANDAAIDMYAGGWSTGYDPNPSGLWGPIAAFNMSRFVSDENTKLLEAISSAESFDDKKNVENYKAWQKYAHEQAFAIPTFESEKITAVNKRVKSYDTKYGSASGTGLAYEGIELTADKGVVAE
>NC_017619.1|WP_002942324.1|1778032_1779031_-|ABC-transporter-ATP-binding-protein
MATEKPLLDIKDLHVGFRIGDDYFDAVDGVDISLQKNEILAIVGESGCGKSTLATTIMGLHNPLNTKITGSIQYNDMELIGMDEAKYNTVRGNDIGMIFQDPLASLNPLMTIGAQIDEALFYHTDLDANARTERVLELLAQVGIPNPKRTFKQYPHELSGGMRQRIIIAMALSCKPPIIIADEPTTALDVTIQAQILDLLNDIQAETGSGIILITHDLGVVAETADRVAVMYGGQFVEVAPVEELFTNPKHPYTRSLLKSNPQSGSEGGDLHVIEGIVPPITKMVRKGCRFAPRIPWIGAEAHEENPSMHEVGPNHFVRCTCHETFYFEGEA
>NC_017619.1|WP_012027759.1|1777088_1778030_-|ABC-transporter-ATP-binding-protein
MGFIEVKDLKVHYPIRSGFFNRVTDHVYAVDGVNIEFEEGKTYGLVGESGSGKSTIGKAIIGLERATSGQIIYEGQDVTNKSRGKKGNFNRDVQMIFQDSLSSFNPKKRILDIIAEPIRNFDRLSPDEEKKKVLQLLDTIGLNEEALIKYPHEFSGGQRQRIGVARALASNPRLIIADEPVSALDLSVQAQVLNYMKRIQDEFKLSYLFISHDLGVVQHMCDELFIMYRGRFVETGNKNDIYNNPQHIYTKRLLSAIPTIDPLNRLKNKEKRLAAEKEYQEMQGQYYDENGRVYDLRSFSETHQVALPEGGQN
>NC_017619.1|WP_002938143.1|1776130_1777087_-|ABC-transporter-permease
MWKTVLRRLLMMIPQIIILSVIAFFVAKMMPGDPFTGLIDPNIDPAIIEQKRIAAGYYDPIPVQYFRWVGNLLQGDFGQSVIFKQPVVDVIMQRLNNTIGLSLLTMVLTYLIALPLGMIAGRYQNSLADKIIGVYNFLTFSTPTFVFAILMLWMFGFSLGWFPTRGSISGGVEGFAATLSRLHHMILPAITMAILSTTVTIQYLRTGIIDAKSQDYVRTARAKGVPERVVYNRHIFRNSILPIASFLGYELTGLIGGSIFIENIFTYPGIGQLFFNSISSRDYSVILALLLVFGMGTLLGTLISDIIMSIVDPRIRVK
>NC_017619.1|WP_012027769.1|1788928_1790101_-|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MIPFALKYIMVIITTMVISAIATPLVRFMSLRVGAVDNPNARRINKVPMPSAGGLAIFVAFTISVLWFLPGIVTRVNYHGTYLHYIWPLVLASSIIVLTGFIDDVKELKPAPKMFGILAAATIIWIFTEFRFDSFKIPFGGPFLQFPVWLSFLLTVLWIVSITNAVNLIDGLDGLVSGVSIISLTTMGIVSYFFLHDSNIFLTLTIFVLVAAIVGFLPYNYNPAIIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPMIILGVPITDTVVAIIRRKLSGQKIYEADKMHLHHRLLSLGLTHRGTVLVIYAISFLFSLTSLLLNVSSRIGGILLLVTMGLGIEILCELIGIFGINRTPLLNLLRFIGNSSYRQEKIAKYKKCCEEKKRK
>NC_017619.1|WP_012775334.1|1790097_1790820_-|adaptor-protein-MecA
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDLDQNLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFTFVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV
>NC_017619.1|WP_012027770.1|1790947_1791784_-|undecaprenyl-diphosphate-phosphatase
MLLELLKAIFLGIIEGVTEWLPVSSTGHLILVQEFVKLNQSKNFLEMFNIVIQLGAILAVMTIYFKKLNPFQPGKTKRDIQLTWQLWAKVVIACIPSILIAVPLDNWFEAHFNFMVPIAIALIVYGIAFIWIENRNRGIEPQVTDLAKMSYKTALLIGCFQVLSIVPGTSRSGATILGAIILGTSRSVAADFTFFLGIPTMFGYSGLKAVKYFLDGNSLNMEQVWILLVASVTAYLVSLVVIRFLTDFVKKHDFTVFGYYRIILGAILLVYAFITFLF
>NC_017619.1|WP_012028491.1|1791910_1793476_+|ABC-transporter-substrate-binding-protein/permease
MKRKLSIFLLTLIAVFSVTTGVRADEYLRVGMEAAYAPFNWTQEDDSNSAVPIEGTNQFANGYDVQVAKKIAASMDKELLVVKTKWEGLVPALTSGKIDMIIAGMSPTEERKKEIAFSDSYYTSIPTLVVRSDSQYANATSLEDFAGAKITAQQGVYLYDLIDQIEGANKQTAMGDFSQIRQALESGIIDAYVSERPEGRTAEAANKAFKMVELADSFETNAEDVTIAVGMRKDDERIAQVNEVLATISEEEQIALMDDMIENQPVEEASEGETPSFFAQVWNIVVNNWQQLLRGTGMTLLISILGTIIGTAIGLLIGVFRTAPKAANKALAIGQKVLGWIINIYIEIFRGTPMIVQSMVIYYGTAQAFGLNLDRTLAAIFIVSINTGAYMSEIVRGGIFAVDKGQFEAATALGFTHNQTMRKIVLPQVIRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTVIAIIYFILTFTVTRILRAVEKYFDTDTYTTGANQMQVEVPHD
>NC_017619.1|WP_012775335.1|1793468_1794212_+|amino-acid-ABC-transporter-ATP-binding-protein
MTKNVILEIKNLKKSYGQNQVLKDISISVEKGEVISIIGSSGSGKSTFLRSINLLETPTEGQILYHGQDVLAKGYDLTTYREKLGMVFQSFNLFNNLNVLENAIVAQTTVLKRDRAEAEKIAKENLNKVGMTEQYWQAKPSQLSGGQKQRVAIARALSVDPEVILFDEPTSALDPEMVGEVLKTMQDLAKSGLTMLIVTHEMEFARDVSDRVIFMDKGVIAEEGSPQQIFENPQEERTREFLQRFLG
>NC_017619.1|WP_009910800.1|1794337_1794547_-|hypothetical-protein
MTSYEKVAAVVGWVREKKITGYRISKETNAREMSVIALAQGRAKIDNISFATALGLIDFYDKNHKKFEN
>NC_017619.1|WP_012027774.1|1794632_1795535_-|SPFH-domain-containing-protein
MVFGPIVFIGSFLFFVLIALILIASGLYVVKQQTVAIIERFGKYQKTSTSGINFKIPFGVDVIAARIQLRMLQSEIVVETKTQDNVFVTMNVATQYRVNENNVTDAYYKLMHPEAQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQKQVAEEMSTYGYVIVKTLITKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQRKAIVDGLADSIRELKESNVSLSEEQIMSILLTNQYLDTLNNFAQGGNQTIFLPGNPEGVEDIRTQILSSLRAK
>NC_017619.1|WP_002937416.1|1795544_1796795_-|threonine-ammonia-lyase-IlvA
MITAKNVEQAYSVLKRVVVRTPLDYSRYLSEKYGATIYLKRENEQRVRSFKIRGAYYAISQLTDDEKSRGVVCASAGNHAQGVAYTCQEMQIPATIFMPITTPQQKIGQVKFFGGDYVEIRLVGDTFDESAKAAQDYTQESGKTFIDPFDDENVQAGQGTVAYEILEEAEEQTISFDQILVPIGGGGLVAGVSAYLKEHAPEIKIVGVEASGARSMKAAFDKGRPVKLDQIDKFADGIAVQKVGKSTYEVARKYVDRLIGVDEGWISGTILDLYSKLGIVAEPAGAATIAALEVVKDQIKGQTICCIISGGNNDINRMPEMEERALIYEGIKHYFVVNFPQRPGALREFVNDILGPNDDITRFEYIKRANKGTGPVLIGIALGDKTDYTQFISRLEEFDPQYINLHENDSLYKMLV
>NC_017619.1|WP_009910803.1|1797077_1798100_-|ketol-acid-reductoisomerase
MTVTMQYEKDVTVAALDGKRIAVIGYGSQGHAHAQNLRDTGHDVIIGVRAGKSFDKAKEDGFETFEVAEAAKQADVIMILAPDEIQADLYNEEIAPNLEAGNALGFAHGFNVHFEFIKVPADVDVFMCAPKGPGHLVRRTFEEGFGVPALYAVYQDATGNAKHIAMDWAKGVGSARVGLLETTFKEETEEDLFGEQAVLCGGLTALMQAGFEVLTEAGYAPELAYFEVLHEMKLIVDLVYEGGFKKMRQSISNTAEFGDYVSGPRVITDQVKENMKAVLADIQSGKFANDFVNDYKAGRPRMEAYRKEAENLEIEKVGAELRKAMPFVGRNDDDAFKIYN
>NC_017619.1|WP_009910805.1|1798240_1798717_-|acetolactate-synthase-small-subunit
MRRMLTAKLRNSSGVLNRFTGVLSRRQINIESISVGPTEVDGISRVTVIVDVVSHDEVEQIIKQLNRLIDVVRVRDLTDIPHLEREVILVKISAPPTKRAEILAIIQPFRANVVDVAPHSITIQMTGDGDKIDALLRVIQPYGIKNIARTGATGFSRD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

31438 : 41700

Microbacterium_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012774881.1\|31438_35158_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	8.6e-39	26.9
WP_014636539.1\|35160_36615_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.5e-58	35.2
WP_012774882.1\|36670_37693_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A127KMF9	Cyanophage	1.3e-58	42.7
WP_011922533.1\|37689_38241_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-26	38.5
WP_011921652.1\|38250_39798_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.6e-74	47.6
WP_011921653.1\|39923_41186_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_011921654.1\|41211_41700_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.7e-17	45.0

DBSCAN-SWA_2

543232 : 556345

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011922101.1\|543232_543871_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.0e-125	99.5
WP_011922102.1\|543933_546447_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	0.0e+00	98.5
WP_011922103.1\|546606_547683_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.5e-193	99.2
WP_011922104.1\|547747_548986_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.0e-217	96.8
WP_011922105.1\|548995_549781_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.0e-130	95.4
WP_011922106.1\|549803_550208_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.2e-64	99.3
WP_002938910.1\|550334_551186_+	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.3e-152	98.6
WP_011922108.1\|551284_552544_-	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	1.2e-239	98.8
WP_012775019.1\|552666_553401_+	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	1.5e-120	99.5
WP_012775020.1\|553505_554951_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	2.4e-226	99.5
WP_011922111.1\|554968_555658_+	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	1.3e-110	96.1
WP_012775429.1\|555667_556345_+	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	8.1e-121	99.1

DBSCAN-SWA_3

637262 : 652607

Streptococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012775040.1\|637262_639500_+	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	1.2e-99	96.7
WP_002935351.1\|639501_639645_+\|transposase	transposase	NA	NA	NA	NA
WP_011922763.1\|639824_640481_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	2.7e-113	98.6
WP_011922194.1\|640574_641402_+	hypothetical protein	M1PFV6	Streptococcus_phage	1.0e-133	98.5
WP_011922195.1\|641407_642679_+	hypothetical protein	M1PLC8	Streptococcus_phage	1.3e-207	98.1
WP_002935357.1\|642715_643582_-	YitT family protein	M1Q1P6	Streptococcus_phage	4.6e-153	99.7
WP_012775041.1\|643756_644395_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.0e-112	98.1
WP_011922767.1\|644391_645276_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	5.6e-154	98.6
WP_002935361.1\|645295_645613_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.1e-54	100.0
WP_002935362.1\|645614_646478_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.1e-158	99.7
WP_011922200.1\|646947_648039_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	2.4e-207	100.0
WP_011922201.1\|648038_648596_+	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	5.9e-93	94.6
WP_011922202.1\|648649_649831_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	7.8e-220	99.7
WP_011922203.1\|649833_650340_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	7.0e-93	97.0
WP_002935368.1\|650323_650677_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.9e-60	100.0
WP_011922204.1\|650693_651593_-	cation transporter	M1Q1N9	Streptococcus_phage	5.1e-163	99.7
WP_012775042.1\|651779_652607_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.9e-152	100.0

DBSCAN-SWA_4

812953 : 819983

Bacillus_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011922359.1\|812953_813793_+	thymidylate synthase	U5J9N5	Bacillus_phage	1.7e-88	55.7
WP_011922360.1\|814078_814591_+	dihydrofolate reductase	A0A076GDN3	Bacillus_phage	1.6e-20	36.6
WP_002934974.1\|814788_816015_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.2e-133	59.2
WP_012775089.1\|816070_816658_+	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_012028095.1\|816680_817094_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	4.3e-24	42.5
WP_011922364.1\|817197_817869_+	membrane protein	A0A1S5SAM6	Streptococcus_phage	3.0e-06	35.2
WP_002943192.1\|818150_819983_+	elongation factor 4	A0A2K9L2P9	Tupanvirus	2.2e-19	38.8

DBSCAN-SWA_5

898123 : 904076

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014636621.1\|898123_899818_-	DUF4368 domain-containing protein	A0A288WFZ3	Bacillus_phage	5.3e-20	25.5
WP_000409924.1\|899899_900754_+	ParA family protein	A0A1X9I765	Streptococcus_phage	4.1e-154	99.3
WP_002321610.1\|900845_901061_+	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	1.4e-31	98.6
WP_002321849.1\|901270_902008_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.7e-135	100.0
WP_073459356.1\|902153_902438_+	topoisomerase	A0A1X9I6W8	Streptococcus_phage	2.3e-40	93.0
WP_000253176.1\|902682_902946_-	hypothetical protein	NA	NA	NA	NA
WP_001206986.1\|902945_903176_-	hypothetical protein	A0A223LEC3	Bacillus_phage	3.2e-13	48.5
WP_000743700.1\|903221_904076_-	ParB/RepB/Spo0J family partition protein	S5VSZ7	Leptospira_phage	1.7e-06	30.2

DBSCAN-SWA_6

1273689 : 1279474

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012027298.1\|1273689_1274439_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	3.4e-27	32.9
WP_012027299.1\|1274601_1275144_-	ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	5.9e-21	35.1
WP_012027300.1\|1275662_1276466_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	2.8e-35	35.6
WP_012027301.1\|1276472_1277822_-	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	2.1e-35	34.5
WP_004298854.1\|1277814_1278519_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-38	39.8
WP_012027304.1\|1278712_1279474_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.0e-34	38.4

DBSCAN-SWA_7

1420031 : 1484072

Streptococcus_phage(95.24%)

terminase,capsid,holin,tail,integrase,portal,transposase,head

attL 1444401:1444420|attR 1480910:1480929

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162144929.1\|1420031_1421324_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.0e-216	95.5
WP_012775258.1\|1421508_1422144_-	phosphoserine phosphatase SerB	NA	NA	NA	NA
WP_012027444.1\|1422195_1423920_-	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_012027445.1\|1424008_1425961_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.1e-141	44.6
WP_012775259.1\|1426142_1426682_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_012027447.1\|1426695_1427925_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_012775260.1\|1429388_1429931_-\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	1.1e-80	78.9
WP_014636468.1\|1429917_1430103_-	hypothetical protein	NA	NA	NA	NA
WP_012027449.1\|1430400_1431933_-	primase	A0A1X9I717	Streptococcus_phage	4.9e-105	42.3
WP_012027450.1\|1431947_1432520_-	hypothetical protein	NA	NA	NA	NA
WP_012027451.1\|1432512_1432713_-	hypothetical protein	NA	NA	NA	NA
WP_012775262.1\|1432724_1432928_-	membrane protein	A0A1X9I5T6	Streptococcus_phage	2.4e-20	73.1
WP_012027452.1\|1432948_1433266_-	hypothetical protein	A0A1X9I5Z6	Streptococcus_phage	1.3e-09	41.0
WP_012027454.1\|1433619_1433883_-	hypothetical protein	A0A1S5S7M1	Streptococcus_phage	1.0e-07	43.8
WP_012775263.1\|1434013_1434421_-	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	1.8e-35	52.2
WP_012027456.1\|1434432_1434750_-	hypothetical protein	NA	NA	NA	NA
WP_012027457.1\|1434736_1434958_-	hypothetical protein	NA	NA	NA	NA
WP_012027458.1\|1434954_1435197_-	hypothetical protein	NA	NA	NA	NA
WP_012027459.1\|1435193_1435394_-	hypothetical protein	NA	NA	NA	NA
WP_014636470.1\|1435383_1435674_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.8e-08	40.7
WP_012027461.1\|1435991_1436180_-	helix-turn-helix transcriptional regulator	R9QNG3	Lactococcus_phage	2.0e-05	42.4
WP_012027462.1\|1436331_1436853_+	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	8.7e-14	65.1
WP_014636658.1\|1436908_1437601_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_012775264.1\|1438288_1439431_+\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	2.5e-69	39.7
WP_014636072.1\|1439533_1439815_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_012027467.1\|1439894_1440923_-	FAD:protein FMN transferase	NA	NA	NA	NA
WP_012028391.1\|1440909_1441854_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_012775265.1\|1441948_1442410_+	flavodoxin	NA	NA	NA	NA
WP_012027470.1\|1442550_1442820_+	30S ribosomal protein S14	NA	NA	NA	NA
WP_012027471.1\|1442901_1443180_+	chorismate mutase	NA	NA	NA	NA
WP_012027472.1\|1443169_1444384_+	voltage-gated chloride channel protein	A0A1X9I5Z9	Streptococcus_phage	4.9e-217	97.0
1444401:1444420	attL	NA	NA	NA	NA
WP_024394270.1\|1444836_1445214_-	hypothetical protein	A0A1X9I733	Streptococcus_phage	1.9e-63	100.0
WP_014636660.1\|1445278_1446016_-	CHAP domain-containing protein	A0A1X9I6R1	Streptococcus_phage	4.2e-139	100.0
WP_002937841.1\|1445999_1446350_-\|holin	phage holin	A0A1X9I630	Streptococcus_phage	2.1e-56	100.0
WP_014636661.1\|1446352_1446652_-	hypothetical protein	A0A1S5SA32	Streptococcus_phage	7.6e-47	100.0
WP_002937844.1\|1446655_1447000_-	hypothetical protein	A0A1X9I644	Streptococcus_phage	8.7e-63	100.0
WP_002937846.1\|1447002_1447221_-	hypothetical protein	A0A1X9I6F7	Streptococcus_phage	1.5e-28	100.0
WP_002936851.1\|1452573_1452924_-	hypothetical protein	A0A1X9I607	Streptococcus_phage	1.3e-61	100.0
WP_002936852.1\|1452933_1456071_-	hypothetical protein	A0A1X9I5Z7	Streptococcus_phage	0.0e+00	100.0
WP_024394260.1\|1456095_1456455_-	hypothetical protein	A0A1X9I602	Streptococcus_phage	2.2e-61	100.0
WP_002936853.1\|1456481_1456856_-	hypothetical protein	A0A1X9I734	Streptococcus_phage	4.1e-66	100.0
WP_002936854.1\|1456866_1457283_-\|tail	tail protein	A0A1X9I6R2	Streptococcus_phage	9.5e-72	100.0
WP_002936856.1\|1457286_1457655_-	hypothetical protein	A0A1X9I641	Streptococcus_phage	1.3e-64	100.0
WP_014636664.1\|1457651_1458164_-	HK97 gp10 family phage protein	A0A1X9I6C1	Streptococcus_phage	1.5e-90	100.0
WP_002936870.1\|1458431_1458761_-\|head,tail	phage head-tail adapter protein	A0A1X9I6G0	Streptococcus_phage	3.3e-51	100.0
WP_002936873.1\|1458770_1458959_-	hypothetical protein	A0A1X9I614	Streptococcus_phage	3.2e-27	100.0
WP_014636666.1\|1458969_1459986_-	sugar-binding protein	A0A1X9I629	Streptococcus_phage	2.1e-189	100.0
WP_002936882.1\|1460003_1460525_-	DUF4355 domain-containing protein	A0A1X9I605	Streptococcus_phage	1.7e-73	100.0
WP_002936883.1\|1460688_1460979_-	hypothetical protein	A0A1X9I606	Streptococcus_phage	3.4e-52	100.0
WP_002936884.1\|1460990_1461227_-	hypothetical protein	A0A1X9I5F6	Streptococcus_phage	1.1e-35	100.0
WP_002936886.1\|1461440_1461641_-	hypothetical protein	A0A1X9I649	Streptococcus_phage	2.2e-34	100.0
WP_014636668.1\|1461609_1463079_-\|capsid	minor capsid protein	M1IF93	Streptococcus_phage	3.8e-272	100.0
WP_014636669.1\|1463008_1464472_-\|portal	phage portal protein	A0A1X9I6D7	Streptococcus_phage	7.6e-273	100.0
WP_014636670.1\|1464484_1465903_-\|terminase	phage terminase large subunit	A0A1X9I5M9	Streptococcus_phage	5.2e-279	100.0
WP_041179310.1\|1465895_1466687_-	HNH endonuclease	A0A1X9I5J3	Streptococcus_phage	8.2e-157	99.6
WP_014636672.1\|1467108_1467516_-	DUF1492 domain-containing protein	A0A1X9I5N2	Streptococcus_phage	1.2e-66	100.0
WP_002937919.1\|1467592_1467844_-	hypothetical protein	M1PFL8	Streptococcus_phage	1.7e-39	100.0
WP_002937922.1\|1467855_1468125_-	hypothetical protein	M1NS18	Streptococcus_phage	1.6e-43	100.0
WP_002937935.1\|1468300_1468534_-	hypothetical protein	M1Q1F5	Streptococcus_phage	1.9e-37	100.0
WP_002937939.1\|1468549_1468852_-	DUF1372 family protein	M1PL25	Streptococcus_phage	9.4e-53	100.0
WP_002937943.1\|1468861_1469380_-	hypothetical protein	M1PFM2	Streptococcus_phage	1.7e-89	100.0
WP_002937944.1\|1469376_1469709_-	hypothetical protein	M1NS23	Streptococcus_phage	5.3e-57	100.0
WP_002937949.1\|1470021_1470396_-	hypothetical protein	M1Q1F9	Streptococcus_phage	2.8e-70	100.0
WP_002937951.1\|1470423_1470885_-	single-stranded DNA-binding protein	M1PL31	Streptococcus_phage	2.0e-70	100.0
WP_002937955.1\|1470987_1471167_-	hypothetical protein	M1NS29	Streptococcus_phage	1.9e-24	100.0
WP_002937956.1\|1471156_1471483_-	hypothetical protein	M1PS51	Streptococcus_phage	6.1e-58	100.0
WP_002937957.1\|1471492_1471762_-	hypothetical protein	M1Q1G3	Streptococcus_phage	1.6e-48	100.0
WP_014636674.1\|1471764_1472793_-	DUF1351 domain-containing protein	M1PL36	Streptococcus_phage	2.0e-134	100.0
WP_014636675.1\|1472802_1473573_-	phage recombination protein Bet	M1PFN1	Streptococcus_phage	4.3e-142	100.0
WP_004195116.1\|1473569_1473749_-	hypothetical protein	A0A1X9I5S5	Streptococcus_phage	2.4e-24	100.0
WP_004194647.1\|1474258_1474624_-	hypothetical protein	A0A1X9I5L0	Streptococcus_phage	5.8e-65	100.0
WP_004194648.1\|1474676_1474901_-	hypothetical protein	A0A1X9I5Q2	Streptococcus_phage	8.3e-30	100.0
WP_014636678.1\|1474881_1475139_-	hypothetical protein	A0A1X9I620	Streptococcus_phage	7.7e-40	100.0
WP_014636680.1\|1475493_1476204_-	oxidoreductase	A0A1X9I742	Streptococcus_phage	2.6e-130	100.0
WP_014636681.1\|1476257_1476947_+	DUF4145 domain-containing protein	A0A1X9I6S1	Streptococcus_phage	4.0e-131	100.0
WP_014636682.1\|1477042_1477264_-	hypothetical protein	A0A1X9I6W7	Streptococcus_phage	1.3e-32	100.0
WP_014636684.1\|1477554_1477761_-	helix-turn-helix transcriptional regulator	A0A1X9I5Q5	Streptococcus_phage	1.1e-31	100.0
WP_014636687.1\|1478303_1479047_+	helix-turn-helix transcriptional regulator	A0A1X9I5R1	Streptococcus_phage	3.6e-138	100.0
WP_014636688.1\|1479221_1479656_+	transcriptional modulatorof MazE/toxin MazF	A0A1X9I6T4	Streptococcus_phage	2.3e-76	100.0
WP_014636689.1\|1479781_1480876_+\|integrase	site-specific integrase	A0A1X9I680	Streptococcus_phage	6.8e-210	100.0
WP_012775266.1\|1481180_1483205_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
1480910:1480929	attR	NA	NA	NA	NA
WP_012028394.1\|1483466_1484072_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.8e-58	55.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017619

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection