CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021184	Desulfallas gibsoniae DSM 7213, complete sequence	10 crisprs	cas8b1,cas7b,cas5,cas3,cas4,cas1,cas2,RT,DinG,cas14j,cas6,cas7,cas9,DEDDh,csa3,cas8c	0	28	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_021184_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_1

34008-34271

Orphan

Consensus_repeat	Method
GGTGCTGGCACGCCATAGGTAGGGTGAAAAC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_021184_1

>merge|NC_021184|1|34008-34271|CRISPRCasFinder
GGTACTGGCCCTTCATAGGTAGGGTGGCCATCCTTTCCATTCCGGCGAATTTGCCGGATTGCTCTGGTACTGGCCCTTCATAGGTAGGGTGGCCATCAGTACCGGACAATCTGTCGGTTACTGAAAATGTGTACTTAACCCCGGTCAAACTATCCCAAGTTGAAGGGTGCTGGCACGCCATAGGTAGGGTGAAAACGCACCTTGTGGAACTCAGTTCCCCAAGGTCAGGATTAGGTGCTGGCACGCCATAGGTAGGGTGAAAAC

>NC_021184|1|1|34008-34271|CRISPRCasFinder
GGTACTGGCCCTTCATAGGTAGGGTGGCCAT	CCTTTCCATTCCGGCGAATTTGCCGGATTGCTCT
GGTACTGGCCCTTCATAGGTAGGGTGGCCAT	CAGTACCGGACAATCTGTCGGTTACTGAAAATGTGTACTTAACCCCGGTCAAACTATCCCAAGTTGAAG
GGTGCTGGCACGCCATAGGTAGGGTGAAAAC	GCACCTTGTGGAACTCAGTTCCCCAAGGTCAGGATTA
GGTGCTGGCACGCCATAGGTAGGGTGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_006524629.1\|26934_27291_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524636.1\|32726_33191_-\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524635.1\|31553_32714_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238884
NC_021184.1\|WP_006524640.1\|35120_35261_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524645.1\|35938_36160_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524639.1\|34600_34831_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NC_021184.1\|WP_006524647.1\|37480_37735_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	unknown	unknown	gnl\|CDD\|273688
NC_021184.1\|WP_006524628.1\|26564_26771_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_041285062.1\|36609_37050_+\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NC_021184.1\|WP_006524634.1\|29532_31557_+\|phage-tail-tape-measure-protein	unknown	unknown	gnl\|CDD\|227605
NC_021184.1\|WP_157872698.1\|38661_39354_+\|futalosine-hydrolase	unknown	unknown	gnl\|CDD\|236194
NC_021184.1\|WP_041284701.1\|33425_33668_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524631.1\|27481_28054_+\|HK97-family-phage-prohead-protease	unknown	unknown	gnl\|CDD\|226263
NC_021184.1\|WP_006524638.1\|34326_34608_-\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524642.1\|35393_35564_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524630.1\|27268_27457_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524643.1\|35567_35792_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524637.1\|33712_34003_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524632.1\|28055_29300_+\|phage-major-capsid-protein	unknown	unknown	gnl\|CDD\|273690
NC_021184.1\|WP_006524648.1\|37727_38060_+\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	unknown	unknown	gnl\|CDD\|226194

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_006524634.1\|29532_31557_+\|phage-tail-tape-measure-protein	gnl\|CDD\|227605	COG5280, COG5280, Phage-related minor tail protein [Function unknown].	1.85073e-34
NC_021184.1\|WP_006524639.1\|34600_34831_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	5.97412e-23
NC_021184.1\|WP_006524632.1\|28055_29300_+\|phage-major-capsid-protein	gnl\|CDD\|273690	TIGR01554, prophage_Lp3_protein_18, phage major capsid protein, HK97 family. This model family represents the major capsid protein component of the heads (capsids) of bacteriophage HK97, phi-105, P27, and related phage. This model represents one of several analogous families lacking detectable sequence similarity. The gene encoding this component is typically located in an operon encoding the small and large terminase subunits, the portal protein and the prohead or maturation protease. [Mobile and extrachromosomal element functions, Prophage functions].	2.52067e-39
NC_021184.1\|WP_006524631.1\|27481_28054_+\|HK97-family-phage-prohead-protease	gnl\|CDD\|226263	COG3740, COG3740, Phage head maturation protease [General function prediction only].	1.81082e-28
NC_021184.1\|WP_157872698.1\|38661_39354_+\|futalosine-hydrolase	gnl\|CDD\|236194	PRK08236, PRK08236, hypothetical protein; Provisional.	3.87091e-90
NC_021184.1\|WP_006524635.1\|31553_32714_+\|hypothetical-protein	gnl\|CDD\|238884	cd01901, Ntn_hydrolase, The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a four-layered alpha, beta, beta, alpha core structure. This family of hydrolases includes penicillin acylase, the 20S proteasome alpha and beta subunits, and glutamate synthase. The mechanism of activation of these proteins is conserved, although they differ in their substrate specificities. All known members catalyze the hydrolysis of amide bonds in either proteins or small molecules, and each one of them is synthesized as a preprotein. For each, an autocatalytic endoproteolytic process generates a new N-terminal residue. This mature N-terminal residue is central to catalysis and acts as both a polarizing base and a nucleophile during the reaction. The N-terminal amino group acts as the proton acceptor and activates either the nucleophilic hydroxyl in a Ser or Thr residue or the nucleophilic thiol in a Cys residue. The position of the N-terminal nucleophile in the active site and the mechanism of catalysis are conserved in this family, despite considerable variation in the protein sequences.	0.00534955
NC_021184.1\|WP_006524647.1\|37480_37735_+\|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin	gnl\|CDD\|273688	TIGR01552, Hypothetical_protein_Rv3357/MT3465/Mb3392., prevent-host-death family protein. This model recognizes a region of about 55 amino acids toward the N-terminal end of bacterial proteins of about 85 amino acids in length. The best-characterized member is prevent-host-death (phd) of bacteriophage P1, the antidote partner of death-on-curing (doc) (TIGR01550) in an addiction module. Addiction modules prevent plasmid curing by killing the host cell as the longer-lived killing protein persists while the gene for the shorter-lived antidote is lost. Note, however, that relatively few members of this family appear to be plasmid or phage-encoded. Also, there is little overlap, except for phage P1 itself, of species with this family and with the doc family. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	1.17666e-06
NC_021184.1\|WP_041285062.1\|36609_37050_+\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	9.22837e-66
NC_021184.1\|WP_006524648.1\|37727_38060_+\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	gnl\|CDD\|226194	COG3668, ParE, Plasmid stabilization system protein [General function prediction only].	5.45048e-18

>NC_021184.1|WP_006524637.1|33712_34003_+|hypothetical-protein
MPTQRTSVGELSSTTEKGKTRDKIAEQIDFPLSGRTLSKGMKIYEAAKDSNKDAQESLKKIDNKESSITAEYKKLFKKDEIPKWAIKYSDYHMPTT
>NC_021184.1|WP_041284701.1|33425_33668_+|hypothetical-protein
MIGLKLHLTPSEKVELARRIEEALGGRQGSNQYQRKEDPQNFAEAQKGESRDIAAKAVGMNRETYRQAKAVNMKSRRNGR
>NC_021184.1|WP_006524636.1|32726_33191_-|hypothetical-protein
MKPKSLLTILVLVLTLLIGCGENNMPKESPEPKAEPPEKVAQSILEYMSYQQWQQLYKYLHPDTRALITEDEFIKMKEDGPVLAIESYQVKEPVLLNSWTDSKGTGKTYKNVAEIPFEITVNLVGNKQPYKASMHLVQDEQGAWKYFSDIPKKD
>NC_021184.1|WP_006524635.1|31553_32714_+|hypothetical-protein
MTLVISANNRDEYALVTGDFLGRKHKDMDYNNPVNHNDSDVELVNNVYKTLKVSDYVLLGAAGCHDLGEWLRKEIQDRAAPDFDLIQCRQLAEEIVEEMRDKRTLRITFDMEPLYLNHLYQENGFAFVLTGFYKEGGTGYVSFESNPDGGTFTEKNCSNNRGYQLFTPANNYRELMDQYFELRDGITPVITTAMAQALCLHHIIVDHMPEHVSREMEILILQKQPGQNKPCFGRIKLTDQSRDSAIKTAGQRYADIFLKPMLQTIVKTKPQKPSGYVNVIKDIAGLGKTMVVLGQAMKKNDMKRINICIDLYVAEVAKVNNSFAGLTPPKELKNYHGYYKKLMSHHTKAVKWLKQFQKTGDIVFIDRLNIEMDNIEKIIDKLKRPV
>NC_021184.1|WP_006524634.1|29532_31557_+|phage-tail-tape-measure-protein
MAGSTIKGISIEFGANTQALTAALADVNQKSRNLQGELSQVQRLLRMDPGNTTLIAQQQQLLGQAVNNSREKLDRLKAAQEQVNEQFRRGDINEAQWRSFQREVAASEQQLQRFEEQLQQVNQTSDNLTLGDKFKTSVSGVADNVKNIISPATLAAGAVAGIGIAAVGVVAQGVNMASSWDQASRQMAAATGLPMEAMGEFEAQAEIMFGNARGSVDEIYAAMTQVQQVFHGSAEETGALADKALVLQQVFGFEVSESIKSVDSLVKNFGIDGNTAFDIITKTSQMAGDKAGDLLDTFNEYSPQFAAMGFSAEEFAGILVKGAQEGAFNLDKVGDAVKEFNIRAQDGSKTTAEGFAAIGLNADEMGAAIAAGGDKAQAAFEATIAGLAAIDDPMKQNQAGAALFGEQWNDVRSKVITAMADGKTALGDFAGATDDAAGKVDGGFGQAMERLKNKFGLVTKEIGEKLAPVLNEMATWIEDHMPEIQATVETAFNVMGKVIEGLTLPIRNIIALLQGDFDQVMENTLHLWGISWDGVKSKGLEVWNSITTGVKNWWSGITSWLSSLNPWGAVSGAWNTFKTNTIQVWSNLVTDAKSWGKNIVQGLWQGISSMGTTLRANVTEFINQNIPEVIRKLLGIHSPSTVAYEIGAKIEDADEKAQLALIEIRKFMERWAVA
>NC_021184.1|WP_006524632.1|28055_29300_+|phage-major-capsid-protein
MNKFKYMTESEIEEYRSQLEAELLTSSPERLKEIDKELTDIAAALAKDEYRRTVGAGPRQQRTAGPIGQMQILGTYGIGTGITNNTNTRGNEPVNGNVYGSSEYRQAFMGFVLTGARSEILEYRANATTLTSDIGTVIPTTIVQKVYEKMSAYSMIWDRITKTNVKGGVSVPTSSLKPTATWVAEGSVSDKQKKPTGSITFNYYKLQCRVAISLEASTVSLEMFESTVVENIYEAMIIAVEQSVVTGTGVGQPLGIVNDNTIPAGQIIDVTAAEISTYGKWAAIIGTIPLAYEAKVNLTLTKKDWDKYIAGMVDANGQPIARINLGLAERPERRVLGYNVVLVDDYLPSFDAANVGDIFGYFVDYKDYIFNSNLQMLYKKYFDEDTDEFVHKSTQLGDGKLAAPHSVILLRKAV
>NC_021184.1|WP_006524631.1|27481_28054_+|HK97-family-phage-prohead-protease
MKLYGFSNELRAAGEENNMLLEGRAIVFDQPTVLYEFDGIEYKEIIASTALDKADMSDVVLRYNHNGEYIVLARTRNKSLTLEKRPDGLYMRATLQSDITSHRDLYNAVKSGLIDKMSFGFAVADDGDSYDSATHTRTIMNIRKLFETSLVDQPAYDQTYVEARSRLEQLADVEEYRKALLIRAKLIRRY
>NC_021184.1|WP_006524630.1|27268_27457_+|hypothetical-protein
MKLPKRGSEILQVIDAWHTLIHQAKAGNLQAIKIFLSLKANNQSGAGTAPGKVVDIDKYPLE
>NC_021184.1|WP_006524629.1|26934_27291_+|hypothetical-protein
MSRPRKPPKTKIKVRDILKYIEQLPPDNPLKQELTPDKLIRIKRYIEELQYLDYIIVGLKSDIEANGEIELYENGNQKTRRTNPALTTYIDTIKAYNALLRQVSEILRGIEIEIAKTW
>NC_021184.1|WP_006524628.1|26564_26771_+|hypothetical-protein
MEVSIIPQKKFECVAGRDYLKARITLIVSAKTKEEKRELRARWEQLEENGSLNELLELVREMEAGSYD
>NC_021184.1|WP_006524638.1|34326_34608_-|hypothetical-protein
MSELEKMLRRVLDEALTEKLQPINERLDDMDQRMGTLEQGQASIVKRLDTLEKGQRKIQKDVSEVKLQLKGVWGDILRLDNRLINQEKITGSR
>NC_021184.1|WP_006524639.1|34600_34831_-|helix-turn-helix-transcriptional-regulator
MIKVHLSKILGAKRINMTEIAQQTGLSRNTVFLLYHEKTERMDFSTLNKLCAALNCQPGDLLEHIPDKEGGATANE
>NC_021184.1|WP_006524640.1|35120_35261_+|hypothetical-protein
MASKRKVIIVPDLLQDYIVLGDVVLVSLRYVKELIGEKREDEAHVS
>NC_021184.1|WP_006524642.1|35393_35564_+|hypothetical-protein
MKTVVFCNFKGMEGPASQFTCIATDDFIMIEESLSQEEKELITFVHGGSLPLAKEA
>NC_021184.1|WP_006524643.1|35567_35792_+|hypothetical-protein
MTVEEKARMKAELKKADAMYFIMKWHNDLYEVASSLTEDNQCTKEVAAASVIEVMKEMQEEIAGRSRGEFDVAG
>NC_021184.1|WP_006524645.1|35938_36160_+|hypothetical-protein
MLQFQHADLFERIYRDVCESVCFHYSLMAKVSLGMKDFLDSKVDGQLQALFTVALHMDVEQETLDEIRAMALG
>NC_021184.1|WP_041285062.1|36609_37050_+|nucleoside-deaminase
MREALAEAEKAYALGEVPVGAVVVLDDKIIGRGHNLRETLLDSTAHAEIIALRQAARHIGDWRLNGSVLYVTLEPCPMCAGAMIQFRVQTLVYGAQDPKAGAVDSIMDVVREPRFNHQVAVVSGVLEDECRAILKRFFKELRGNKK
>NC_021184.1|WP_006524647.1|37480_37735_+|type-II-toxin-antitoxin-system-prevent-host-death-family-antitoxin
MPNIKPISDLRNYNEVLRDIAIGEPVFLTKNGRGKFAIVDINEYEKLKASLKLMSQLAQGEQAGKEKGWMTIKEVEAELGIENV
>NC_021184.1|WP_006524648.1|37727_38060_+|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family
MYKLKISPEAKDDLAEIKSYISQELCNPQAAVNLISKITKKIRGLSEHPGIGAPLSSVVDIQTDYRFLVCTNYLIFYRYEDGFVFVSRILYGKRNYTRILFGNLPEDEEK
>NC_021184.1|WP_157872698.1|38661_39354_+|futalosine-hydrolase
MNMVTSPYKRELGKRVLIMTAVQAEMEVVLSGLHRDRGSDKGIDVLVAGIGPVAAAVSTLKALLTAEYNLVVNAGIGGGFSGRAEVGSLVVANKIVAADLGVETFEGFSNLDELSLGTTSIQVDNGLVQGVTEALLAAGLPVKTGPVLTVSTVTGTAESAAKLAARVPGAAAEAMEGYGVAVAAREQGLPIIELRAISNLVGPRDRAAWRIKDALGVLEKASLVLSEVLL

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Crispr_ID: NC_021184_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_2

529607-534559

TypeI-B

Consensus_repeat	Method
GTGGAACCAACACATTTGATGTATTGAAAT	PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	CRT

75 spacers

cas2,cas1,cas4,cas3,cas5,cas7b,cas8b1,RT

The CRISPR arrays of NC_021184_2

>merge|NC_021184|2|529607-534559|PILER-CR,CRISPRCasFinder,CRT
GTGGAACCAACACATTTGATGTATTGAAATCGATATGTAGCATAATATACTTAACGTATTATATTAGTGGAACCAACACATTTGATGTATTGAAATTTCTAGCCACAGCCACGGATCCACCGCGGCTTTCGTGGAACCAACACATTTGATGTATTGAAATAGGGCTAAAAAGCCCCAGAGATTTACCCTCCCCCTCGTGGAACCAACACATTTGATGTATTGAAATATGTTGCGTGGGTGGTAAAGAAGAACAAAACAATGCGTGGAACCAACACATTTGATGTATTGAAATATCTGCCACTGTGCCCTTGTGTACTCTTGCTTGGTTGTGGAACCAACACATTTGATGTATTGAAATATCAACATTGCTCACTTCCCCCTATTGAAAAATAAAGTGGAACCAACACATTTGATGTATTGAAATCTTTTTAAACAGTTTTTCATCTAGTTGCCTGGCCACGTGGAACCAACACATTTGATGTATTGAAATAAGTAAAACCATGCTCTCGTAAAGTGTCCGGTACAAGTGGAACCAACACATTTGATGTATTGAAATAGTGAGGGAGGTGCGATATTTGGAGAGGCCGATTTGTGGAACCAACACATTTGATGTATTGAAATCTTGGTAGTTAACTGTTTGCAGGTAGTTTTTTAGAGTGGAACCAACACATTTGATGTATTGAAATATTACACCGTGGGATGATTATTGCAGCGCATTGGCCAGTGGAACCAACACATTTGATGTATTGAAATTCATTACCCCCGTTACCCTTCCTTGGCCTCCCCCGCCGTGGAACCAACACATTTGATGTATTGAAATTTTTTTAGGTCTTCTTTGATGGAGACAACCAATGCGTGGAACCAACACATTTGATGTATTGAAATAATTTTGTACCCCAGATAATGCGCTCCAGCGCCCTGTGGAACCAACACATTTGATGTATTGAAATATATAACAAGTGGTCGGCTTTATCTGCGCAATGCACGTGGAACCAACACATTTGATGTATTGAAATTTGGTTCTTATTGGCATTCTCATTCTGAATATCTCCTGTGGAACCAACACATTTGATGTATTGAAATATGCTTATCGTAGCGGTGCCATTTATGGGAACGGTGTGGAACCAACACATTTGATGTATTGAAATGACTTACAGGCGGCCGGACCCAACTACCTGGAGAGTGGAACCAACACATTTGATGTATTGAAATCCTTGCCGTCCTTGGCCGGTGGAGCTATGCTGTACGTGGAACCAACACATTTGATGTATTGAAATACGAAATAGGATTCAGGGTAGACGTTGGTGGCCTTGTGGAACCAACACATTTGATGTATTGAAATATGTTTATATCACTGTCTCCGGAAGCGGTGTAAAAGGTGGAACCAACACATTTGATGTATTGAAATTCGGTATAAATCAGGGTGTTTTCCCGAGTAAGCGTACGTGGAACCAACACATTTGATGTATTGAAATCATTCATCTTTCCACATAAGCTCTCTCGCATCCTGTGTGGAACCAACACATTTGATGTATTGAAATACGTTGATATAACCGAAAAGGACCGTGAGCGGTAGTGGAACCAACACATTTGATGTATTGAAATTTGTGACGCTCTTTGTAATAATGGCAGCGTGGGCAGGTGGAACCAACACATTTGATGTATTGAAATATCTTTCCAACCCGGCACCATTGATTTGCCTTTAAGTGGAACCAACACATTTGATGTATTGAAATAAGTTTGACCCCGCACTCACTAAGACATACGCATACGTGGAACCAACACATTTGATGTATTGAAATATCTTTGATTTACCCATCACCCGACCTGCCTTTCCGTGGAACCAACACATTTGATGTATTGAAATTATTTCTGATTCCAGCTTGCTTCGGCTGGAAAGTGTGGAACCAACACATTTGATGTATTGAAATATGCCATAGACTTTTTTAATAGCTTCATAAATAACGTGGAACCAACACATTTGATGTATTGAAATCATCACCGCAGGCCAATTTCCAGGCTGTCTGTCATGTGGAACCAACACATTTGATGTATTGAAATACCGTTACTCCAATCCTGGCGAGGTAGTATATGATCGTGGAACCAACACATTTGATGTATTGAAATCTGGTTCACTCTGTAAATAGCGGTAAACTCTGTGTAGTGGAACCAACACATTTGATGTATTGAAATCTACCCCCGCCCCCTCTCGTCTAACTCAGCTAAGGCGTGGAACCAACACATTTGATGTATTGAAATTTTAATGCCCGAGCACTGGCCGCCCCGCGTTCCCGGTGGAACCAACACATTTGATGTATTGAAATATAGCACGATCAAATACCCACAGGCCGAGGTTATAGTGGAACCAACACATTTGATGTATTGAAATCTGCCTATTCGGGAGATTTACCGTATTTGGGGAAGAGTGGAACCAACACATTTGATGTATTGAAATAACAACGTCGGCCCAAAGTCACACCTGTCTATAGCGTGGAACCAACACATTTGATGTATTGAAATTTTCGAAGAATAGTTTAATAGCCTGGATGTTCCCAGTGGAACCAACACATTTGATGTATTGAAATCAGAATTAAGTGGGGCGTGTTTGAGAAGTTGGAGTTGTGGAACCAACACATTTGATGTATTGAAATTGTGAAGATTATTAACCTGATTGGTTGTGTCGATGGTGGAACCAACACATTTGATGTATTGAAATGTGGGGGGATGAACACCTGCTTGCCGATGCCCTGGTGGAACCAACACATTTGATGTATTGAAATAAAAATTGGAGGTGCGGTAAATGTTAAAAGTGGTTACGTGGAACCAACACATTTGATGTATTGAAATAACTCCAAAACAAGGAAATGACAGGCAAGCAATTCTCGTGGAACCAACACATTTGATGTATTGAAATCGAGAATGTACCAGATGAATTTATTGTGCAGGTAAGTGGAACCAACACATTTGATGTATTGAAATAGCTCAACCACTGGTAACGTGACCGGTATTTTTGATGTGGAACCAACACATTTGATGTATTGAAATTCGTAACGATGACACCCAGTGGCTCGGTCATGTCCACGTGGAACCAACACATTTGATGTATTGAAATACCAGCAGAAGGCGGACATATCAAACCAGCGTGAGGTGGAACCAACACATTTGATGTATTGAAATAAATCAAGGCGTTACTACTATGATTATGAAGCCATTGTGGAACCAACACATTTGATGTATTGAAATATGGGCAGAAACACCCAATAAATCCAAAGGCAGGCGTGGAACCAACAAATTTGATGTATTGAAATAACATAAGGTTTATGTGATGGGAGGTGAGAAAATGTGTGGAACCAACACATTTGATGTATTGAAATTAAAACAAGCCCGACGGTTTGTCAGGTGGGAAGTTTGTGGAACCAACACATTTGATGTATTGAAATATTCAATATCCCCTTACCTTACCGTCCATCCAAGCAGTGGAACCAACACATTTGATGTATTGAAATCTATAAAATAGGGAGGATCAGTATGTTTAACATTGAGTGGAACCAACACATTTGATGTATTGAAATGAGTACATCCGCGTGGCCCTGGTGGGCTGCACTCTGGTGGAACCAACACATTTGATGTATTGAAATGTTGCCGAATATAGCGCAAGTATTAGTAAGGTATAGTGGAACCAACACATTTGATGTATTGAAATTGGACAGGATGATGTTGATTGTGGCGATGACCAGTGCGTGGAACCAACACATTTGATGTATTGAAATCCTAGTTGATGGAAAGATCGTTCCATTCAACTCTAACGTGGAACCAACACATTTGATGTATTGAAATATGGACTACAAAATTTTCTACTACGAGATTTCACGTGGAACCAACACATTTGATGTATTGAAATTAAATAAGGCCTTCGGCAACTACCCAAAGGCCAGTAGTGGAACCAACACATTTGATGTATTGAAATCCGAAATTAATGCTGTTATGTCTCCCAAAATGTTTGTGGAACCAACACATTTGATGTATTGAAATAACTGATTCTATGGTATCTCTTAATGTGGATCTTGCGTGGAACCAACACATTTGATGTATTGAAATGGCGATAGGCAAATGTGTACATTTTGTGAAAATCGAGTGGAACCAACACATTTGATGTATTGAAATAGAAGTGGGAGCAGCATAATTACCTAGTGGAGAAAGTGGAACCAACACATTTGATGTATTGAAATCTGTCGTACTTGGTTCTTGCCATTTCTGAACCTTATGTGGAACCAACACATTTGATGTATTGAAATATGCAGGTTAAATCCTCAACTCCGGAAGGTACTGACGTGGAACCAACACATTTGATGTATTGAAATATTTCAACCTGGTTATTACCGATTGTCGATATCTAAGTGGAACCAACACATTTGATGTATTGAAATCCACCTTTCAGCCGACTGGAGGATATCGCTAATTAGTGGAACCAACACATTTGATGTATTGAAATTACCATAGCCATCGCATGTCTGTTAAATGGTGATTACGTGGAACCAACACATTTGATGTATTGAAATTTGCTAGTAAAAGCGAATGCGCTTTTATTTTTTACATGTGGAACCAACACATTTGATGTATTGAAATAGTTCACGTATTCCAGATTTCACACGGGTCATTTTGTGGAACCAACACATTTGATGTATTGAAATAGTAGATTGGCATGAGCTTCGGGCCTGTGACTATGGGTGGAACCAACACATTTGATGTATTGAAATATATCTGGGCGTCTGTCTGCAAAATGAGGGCGACGTGGAACCAACACATTTGATGTATTGAAATTTTATTGCATTTTTTATTATCAGTGTTTTCATAATTGTGGAACCAACACATTTGATGTATTGAAATAAATATCCGGCCGCATCCAGAACATCTTCAACGCCCGTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|2|1|529607-534559|PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	CGATATGTAGCATAATATACTTAACGTATTATATTA
GTGGAACCAACACATTTGATGTATTGAAAT	TTCTAGCCACAGCCACGGATCCACCGCGGCTTTC
GTGGAACCAACACATTTGATGTATTGAAAT	AGGGCTAAAAAGCCCCAGAGATTTACCCTCCCCCTC
GTGGAACCAACACATTTGATGTATTGAAAT	ATGTTGCGTGGGTGGTAAAGAAGAACAAAACAATGC
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTGCCACTGTGCCCTTGTGTACTCTTGCTTGGTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATCAACATTGCTCACTTCCCCCTATTGAAAAATAAA
GTGGAACCAACACATTTGATGTATTGAAAT	CTTTTTAAACAGTTTTTCATCTAGTTGCCTGGCCAC
GTGGAACCAACACATTTGATGTATTGAAAT	AAGTAAAACCATGCTCTCGTAAAGTGTCCGGTACAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGTGAGGGAGGTGCGATATTTGGAGAGGCCGATTT
GTGGAACCAACACATTTGATGTATTGAAAT	CTTGGTAGTTAACTGTTTGCAGGTAGTTTTTTAGA
GTGGAACCAACACATTTGATGTATTGAAAT	ATTACACCGTGGGATGATTATTGCAGCGCATTGGCCA
GTGGAACCAACACATTTGATGTATTGAAAT	TCATTACCCCCGTTACCCTTCCTTGGCCTCCCCCGCC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTTTTAGGTCTTCTTTGATGGAGACAACCAATGC
GTGGAACCAACACATTTGATGTATTGAAAT	AATTTTGTACCCCAGATAATGCGCTCCAGCGCCCT
GTGGAACCAACACATTTGATGTATTGAAAT	ATATAACAAGTGGTCGGCTTTATCTGCGCAATGCAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTGGTTCTTATTGGCATTCTCATTCTGAATATCTCCT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCTTATCGTAGCGGTGCCATTTATGGGAACGGT
GTGGAACCAACACATTTGATGTATTGAAAT	GACTTACAGGCGGCCGGACCCAACTACCTGGAGA
GTGGAACCAACACATTTGATGTATTGAAAT	CCTTGCCGTCCTTGGCCGGTGGAGCTATGCTGTAC
GTGGAACCAACACATTTGATGTATTGAAAT	ACGAAATAGGATTCAGGGTAGACGTTGGTGGCCTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGTTTATATCACTGTCTCCGGAAGCGGTGTAAAAG
GTGGAACCAACACATTTGATGTATTGAAAT	TCGGTATAAATCAGGGTGTTTTCCCGAGTAAGCGTAC
GTGGAACCAACACATTTGATGTATTGAAAT	CATTCATCTTTCCACATAAGCTCTCTCGCATCCTGT
GTGGAACCAACACATTTGATGTATTGAAAT	ACGTTGATATAACCGAAAAGGACCGTGAGCGGTA
GTGGAACCAACACATTTGATGTATTGAAAT	TTGTGACGCTCTTTGTAATAATGGCAGCGTGGGCAG
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTTCCAACCCGGCACCATTGATTTGCCTTTAA
GTGGAACCAACACATTTGATGTATTGAAAT	AAGTTTGACCCCGCACTCACTAAGACATACGCATAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTTGATTTACCCATCACCCGACCTGCCTTTCC
GTGGAACCAACACATTTGATGTATTGAAAT	TATTTCTGATTCCAGCTTGCTTCGGCTGGAAAGT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCCATAGACTTTTTTAATAGCTTCATAAATAAC
GTGGAACCAACACATTTGATGTATTGAAAT	CATCACCGCAGGCCAATTTCCAGGCTGTCTGTCAT
GTGGAACCAACACATTTGATGTATTGAAAT	ACCGTTACTCCAATCCTGGCGAGGTAGTATATGATC
GTGGAACCAACACATTTGATGTATTGAAAT	CTGGTTCACTCTGTAAATAGCGGTAAACTCTGTGTA
GTGGAACCAACACATTTGATGTATTGAAAT	CTACCCCCGCCCCCTCTCGTCTAACTCAGCTAAGGC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTAATGCCCGAGCACTGGCCGCCCCGCGTTCCCG
GTGGAACCAACACATTTGATGTATTGAAAT	ATAGCACGATCAAATACCCACAGGCCGAGGTTATA
GTGGAACCAACACATTTGATGTATTGAAAT	CTGCCTATTCGGGAGATTTACCGTATTTGGGGAAGA
GTGGAACCAACACATTTGATGTATTGAAAT	AACAACGTCGGCCCAAAGTCACACCTGTCTATAGC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTCGAAGAATAGTTTAATAGCCTGGATGTTCCCA
GTGGAACCAACACATTTGATGTATTGAAAT	CAGAATTAAGTGGGGCGTGTTTGAGAAGTTGGAGTT
GTGGAACCAACACATTTGATGTATTGAAAT	TGTGAAGATTATTAACCTGATTGGTTGTGTCGATG
GTGGAACCAACACATTTGATGTATTGAAAT	GTGGGGGGATGAACACCTGCTTGCCGATGCCCTG
GTGGAACCAACACATTTGATGTATTGAAAT	AAAAATTGGAGGTGCGGTAAATGTTAAAAGTGGTTAC
GTGGAACCAACACATTTGATGTATTGAAAT	AACTCCAAAACAAGGAAATGACAGGCAAGCAATTCTC
GTGGAACCAACACATTTGATGTATTGAAAT	CGAGAATGTACCAGATGAATTTATTGTGCAGGTAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGCTCAACCACTGGTAACGTGACCGGTATTTTTGAT
GTGGAACCAACACATTTGATGTATTGAAAT	TCGTAACGATGACACCCAGTGGCTCGGTCATGTCCAC
GTGGAACCAACACATTTGATGTATTGAAAT	ACCAGCAGAAGGCGGACATATCAAACCAGCGTGAG
GTGGAACCAACACATTTGATGTATTGAAAT	AAATCAAGGCGTTACTACTATGATTATGAAGCCATT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGGGCAGAAACACCCAATAAATCCAAAGGCAGGC
GTGGAACCAACAAATTTGATGTATTGAAAT	AACATAAGGTTTATGTGATGGGAGGTGAGAAAATGT
GTGGAACCAACACATTTGATGTATTGAAAT	TAAAACAAGCCCGACGGTTTGTCAGGTGGGAAGTTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATTCAATATCCCCTTACCTTACCGTCCATCCAAGCA
GTGGAACCAACACATTTGATGTATTGAAAT	CTATAAAATAGGGAGGATCAGTATGTTTAACATTGA
GTGGAACCAACACATTTGATGTATTGAAAT	GAGTACATCCGCGTGGCCCTGGTGGGCTGCACTCTG
GTGGAACCAACACATTTGATGTATTGAAAT	GTTGCCGAATATAGCGCAAGTATTAGTAAGGTATA
GTGGAACCAACACATTTGATGTATTGAAAT	TGGACAGGATGATGTTGATTGTGGCGATGACCAGTGC
GTGGAACCAACACATTTGATGTATTGAAAT	CCTAGTTGATGGAAAGATCGTTCCATTCAACTCTAAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATGGACTACAAAATTTTCTACTACGAGATTTCAC
GTGGAACCAACACATTTGATGTATTGAAAT	TAAATAAGGCCTTCGGCAACTACCCAAAGGCCAGTA
GTGGAACCAACACATTTGATGTATTGAAAT	CCGAAATTAATGCTGTTATGTCTCCCAAAATGTTT
GTGGAACCAACACATTTGATGTATTGAAAT	AACTGATTCTATGGTATCTCTTAATGTGGATCTTGC
GTGGAACCAACACATTTGATGTATTGAAAT	GGCGATAGGCAAATGTGTACATTTTGTGAAAATCGA
GTGGAACCAACACATTTGATGTATTGAAAT	AGAAGTGGGAGCAGCATAATTACCTAGTGGAGAAA
GTGGAACCAACACATTTGATGTATTGAAAT	CTGTCGTACTTGGTTCTTGCCATTTCTGAACCTTAT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCAGGTTAAATCCTCAACTCCGGAAGGTACTGAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATTTCAACCTGGTTATTACCGATTGTCGATATCTAA
GTGGAACCAACACATTTGATGTATTGAAAT	CCACCTTTCAGCCGACTGGAGGATATCGCTAATTA
GTGGAACCAACACATTTGATGTATTGAAAT	TACCATAGCCATCGCATGTCTGTTAAATGGTGATTAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTGCTAGTAAAAGCGAATGCGCTTTTATTTTTTACAT
GTGGAACCAACACATTTGATGTATTGAAAT	AGTTCACGTATTCCAGATTTCACACGGGTCATTTT
GTGGAACCAACACATTTGATGTATTGAAAT	AGTAGATTGGCATGAGCTTCGGGCCTGTGACTATGG
GTGGAACCAACACATTTGATGTATTGAAAT	ATATCTGGGCGTCTGTCTGCAAAATGAGGGCGAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTATTGCATTTTTTATTATCAGTGTTTTCATAATT
GTGGAACCAACACATTTGATGTATTGAAAT	AAATATCCGGCCGCATCCAGAACATCTTCAACGCCC
GTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|2|2|529607-534559|CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	CGATATGTAGCATAATATACTTAACGTATTATATTA
GTGGAACCAACACATTTGATGTATTGAAAT	TTCTAGCCACAGCCACGGATCCACCGCGGCTTTC
GTGGAACCAACACATTTGATGTATTGAAAT	AGGGCTAAAAAGCCCCAGAGATTTACCCTCCCCCTC
GTGGAACCAACACATTTGATGTATTGAAAT	ATGTTGCGTGGGTGGTAAAGAAGAACAAAACAATGC
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTGCCACTGTGCCCTTGTGTACTCTTGCTTGGTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATCAACATTGCTCACTTCCCCCTATTGAAAAATAAA
GTGGAACCAACACATTTGATGTATTGAAAT	CTTTTTAAACAGTTTTTCATCTAGTTGCCTGGCCAC
GTGGAACCAACACATTTGATGTATTGAAAT	AAGTAAAACCATGCTCTCGTAAAGTGTCCGGTACAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGTGAGGGAGGTGCGATATTTGGAGAGGCCGATTT
GTGGAACCAACACATTTGATGTATTGAAAT	CTTGGTAGTTAACTGTTTGCAGGTAGTTTTTTAGA
GTGGAACCAACACATTTGATGTATTGAAAT	ATTACACCGTGGGATGATTATTGCAGCGCATTGGCCA
GTGGAACCAACACATTTGATGTATTGAAAT	TCATTACCCCCGTTACCCTTCCTTGGCCTCCCCCGCC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTTTTAGGTCTTCTTTGATGGAGACAACCAATGC
GTGGAACCAACACATTTGATGTATTGAAAT	AATTTTGTACCCCAGATAATGCGCTCCAGCGCCCT
GTGGAACCAACACATTTGATGTATTGAAAT	ATATAACAAGTGGTCGGCTTTATCTGCGCAATGCAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTGGTTCTTATTGGCATTCTCATTCTGAATATCTCCT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCTTATCGTAGCGGTGCCATTTATGGGAACGGT
GTGGAACCAACACATTTGATGTATTGAAAT	GACTTACAGGCGGCCGGACCCAACTACCTGGAGA
GTGGAACCAACACATTTGATGTATTGAAAT	CCTTGCCGTCCTTGGCCGGTGGAGCTATGCTGTAC
GTGGAACCAACACATTTGATGTATTGAAAT	ACGAAATAGGATTCAGGGTAGACGTTGGTGGCCTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGTTTATATCACTGTCTCCGGAAGCGGTGTAAAAG
GTGGAACCAACACATTTGATGTATTGAAAT	TCGGTATAAATCAGGGTGTTTTCCCGAGTAAGCGTAC
GTGGAACCAACACATTTGATGTATTGAAAT	CATTCATCTTTCCACATAAGCTCTCTCGCATCCTGT
GTGGAACCAACACATTTGATGTATTGAAAT	ACGTTGATATAACCGAAAAGGACCGTGAGCGGTA
GTGGAACCAACACATTTGATGTATTGAAAT	TTGTGACGCTCTTTGTAATAATGGCAGCGTGGGCAG
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTTCCAACCCGGCACCATTGATTTGCCTTTAA
GTGGAACCAACACATTTGATGTATTGAAAT	AAGTTTGACCCCGCACTCACTAAGACATACGCATAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTTGATTTACCCATCACCCGACCTGCCTTTCC
GTGGAACCAACACATTTGATGTATTGAAAT	TATTTCTGATTCCAGCTTGCTTCGGCTGGAAAGT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCCATAGACTTTTTTAATAGCTTCATAAATAAC
GTGGAACCAACACATTTGATGTATTGAAAT	CATCACCGCAGGCCAATTTCCAGGCTGTCTGTCAT
GTGGAACCAACACATTTGATGTATTGAAAT	ACCGTTACTCCAATCCTGGCGAGGTAGTATATGATC
GTGGAACCAACACATTTGATGTATTGAAAT	CTGGTTCACTCTGTAAATAGCGGTAAACTCTGTGTA
GTGGAACCAACACATTTGATGTATTGAAAT	CTACCCCCGCCCCCTCTCGTCTAACTCAGCTAAGGC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTAATGCCCGAGCACTGGCCGCCCCGCGTTCCCG
GTGGAACCAACACATTTGATGTATTGAAAT	ATAGCACGATCAAATACCCACAGGCCGAGGTTATA
GTGGAACCAACACATTTGATGTATTGAAAT	CTGCCTATTCGGGAGATTTACCGTATTTGGGGAAGA
GTGGAACCAACACATTTGATGTATTGAAAT	AACAACGTCGGCCCAAAGTCACACCTGTCTATAGC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTCGAAGAATAGTTTAATAGCCTGGATGTTCCCA
GTGGAACCAACACATTTGATGTATTGAAAT	CAGAATTAAGTGGGGCGTGTTTGAGAAGTTGGAGTT
GTGGAACCAACACATTTGATGTATTGAAAT	TGTGAAGATTATTAACCTGATTGGTTGTGTCGATG
GTGGAACCAACACATTTGATGTATTGAAAT	GTGGGGGGATGAACACCTGCTTGCCGATGCCCTG
GTGGAACCAACACATTTGATGTATTGAAAT	AAAAATTGGAGGTGCGGTAAATGTTAAAAGTGGTTAC
GTGGAACCAACACATTTGATGTATTGAAAT	AACTCCAAAACAAGGAAATGACAGGCAAGCAATTCTC
GTGGAACCAACACATTTGATGTATTGAAAT	CGAGAATGTACCAGATGAATTTATTGTGCAGGTAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGCTCAACCACTGGTAACGTGACCGGTATTTTTGAT
GTGGAACCAACACATTTGATGTATTGAAAT	TCGTAACGATGACACCCAGTGGCTCGGTCATGTCCAC
GTGGAACCAACACATTTGATGTATTGAAAT	ACCAGCAGAAGGCGGACATATCAAACCAGCGTGAG
GTGGAACCAACACATTTGATGTATTGAAAT	AAATCAAGGCGTTACTACTATGATTATGAAGCCATT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGGGCAGAAACACCCAATAAATCCAAAGGCAGGC
GTGGAACCAACAAATTTGATGTATTGAAAT	AACATAAGGTTTATGTGATGGGAGGTGAGAAAATGT
GTGGAACCAACACATTTGATGTATTGAAAT	TAAAACAAGCCCGACGGTTTGTCAGGTGGGAAGTTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATTCAATATCCCCTTACCTTACCGTCCATCCAAGCA
GTGGAACCAACACATTTGATGTATTGAAAT	CTATAAAATAGGGAGGATCAGTATGTTTAACATTGA
GTGGAACCAACACATTTGATGTATTGAAAT	GAGTACATCCGCGTGGCCCTGGTGGGCTGCACTCTG
GTGGAACCAACACATTTGATGTATTGAAAT	GTTGCCGAATATAGCGCAAGTATTAGTAAGGTATA
GTGGAACCAACACATTTGATGTATTGAAAT	TGGACAGGATGATGTTGATTGTGGCGATGACCAGTGC
GTGGAACCAACACATTTGATGTATTGAAAT	CCTAGTTGATGGAAAGATCGTTCCATTCAACTCTAAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATGGACTACAAAATTTTCTACTACGAGATTTCAC
GTGGAACCAACACATTTGATGTATTGAAAT	TAAATAAGGCCTTCGGCAACTACCCAAAGGCCAGTA
GTGGAACCAACACATTTGATGTATTGAAAT	CCGAAATTAATGCTGTTATGTCTCCCAAAATGTTT
GTGGAACCAACACATTTGATGTATTGAAAT	AACTGATTCTATGGTATCTCTTAATGTGGATCTTGC
GTGGAACCAACACATTTGATGTATTGAAAT	GGCGATAGGCAAATGTGTACATTTTGTGAAAATCGA
GTGGAACCAACACATTTGATGTATTGAAAT	AGAAGTGGGAGCAGCATAATTACCTAGTGGAGAAA
GTGGAACCAACACATTTGATGTATTGAAAT	CTGTCGTACTTGGTTCTTGCCATTTCTGAACCTTAT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCAGGTTAAATCCTCAACTCCGGAAGGTACTGAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATTTCAACCTGGTTATTACCGATTGTCGATATCTAA
GTGGAACCAACACATTTGATGTATTGAAAT	CCACCTTTCAGCCGACTGGAGGATATCGCTAATTA
GTGGAACCAACACATTTGATGTATTGAAAT	TACCATAGCCATCGCATGTCTGTTAAATGGTGATTAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTGCTAGTAAAAGCGAATGCGCTTTTATTTTTTACAT
GTGGAACCAACACATTTGATGTATTGAAAT	AGTTCACGTATTCCAGATTTCACACGGGTCATTTT
GTGGAACCAACACATTTGATGTATTGAAAT	AGTAGATTGGCATGAGCTTCGGGCCTGTGACTATGG
GTGGAACCAACACATTTGATGTATTGAAAT	ATATCTGGGCGTCTGTCTGCAAAATGAGGGCGAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTATTGCATTTTTTATTATCAGTGTTTTCATAATT
GTGGAACCAACACATTTGATGTATTGAAAT	AAATATCCGGCCGCATCCAGAACATCTTCAACGCCC
GTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|2|1|529607-534559|CRT
GTGGAACCAACACATTTGATGTATTGAAAT	CGATATGTAGCATAATATACTTAACGTATTATATTA
GTGGAACCAACACATTTGATGTATTGAAAT	TTCTAGCCACAGCCACGGATCCACCGCGGCTTTC
GTGGAACCAACACATTTGATGTATTGAAAT	AGGGCTAAAAAGCCCCAGAGATTTACCCTCCCCCTC
GTGGAACCAACACATTTGATGTATTGAAAT	ATGTTGCGTGGGTGGTAAAGAAGAACAAAACAATGC
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTGCCACTGTGCCCTTGTGTACTCTTGCTTGGTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATCAACATTGCTCACTTCCCCCTATTGAAAAATAAA
GTGGAACCAACACATTTGATGTATTGAAAT	CTTTTTAAACAGTTTTTCATCTAGTTGCCTGGCCAC
GTGGAACCAACACATTTGATGTATTGAAAT	AAGTAAAACCATGCTCTCGTAAAGTGTCCGGTACAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGTGAGGGAGGTGCGATATTTGGAGAGGCCGATTT
GTGGAACCAACACATTTGATGTATTGAAAT	CTTGGTAGTTAACTGTTTGCAGGTAGTTTTTTAGA
GTGGAACCAACACATTTGATGTATTGAAAT	ATTACACCGTGGGATGATTATTGCAGCGCATTGGCCA
GTGGAACCAACACATTTGATGTATTGAAAT	TCATTACCCCCGTTACCCTTCCTTGGCCTCCCCCGCC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTTTTAGGTCTTCTTTGATGGAGACAACCAATGC
GTGGAACCAACACATTTGATGTATTGAAAT	AATTTTGTACCCCAGATAATGCGCTCCAGCGCCCT
GTGGAACCAACACATTTGATGTATTGAAAT	ATATAACAAGTGGTCGGCTTTATCTGCGCAATGCAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTGGTTCTTATTGGCATTCTCATTCTGAATATCTCCT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCTTATCGTAGCGGTGCCATTTATGGGAACGGT
GTGGAACCAACACATTTGATGTATTGAAAT	GACTTACAGGCGGCCGGACCCAACTACCTGGAGA
GTGGAACCAACACATTTGATGTATTGAAAT	CCTTGCCGTCCTTGGCCGGTGGAGCTATGCTGTAC
GTGGAACCAACACATTTGATGTATTGAAAT	ACGAAATAGGATTCAGGGTAGACGTTGGTGGCCTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGTTTATATCACTGTCTCCGGAAGCGGTGTAAAAG
GTGGAACCAACACATTTGATGTATTGAAAT	TCGGTATAAATCAGGGTGTTTTCCCGAGTAAGCGTAC
GTGGAACCAACACATTTGATGTATTGAAAT	CATTCATCTTTCCACATAAGCTCTCTCGCATCCTGT
GTGGAACCAACACATTTGATGTATTGAAAT	ACGTTGATATAACCGAAAAGGACCGTGAGCGGTA
GTGGAACCAACACATTTGATGTATTGAAAT	TTGTGACGCTCTTTGTAATAATGGCAGCGTGGGCAG
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTTCCAACCCGGCACCATTGATTTGCCTTTAA
GTGGAACCAACACATTTGATGTATTGAAAT	AAGTTTGACCCCGCACTCACTAAGACATACGCATAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTTGATTTACCCATCACCCGACCTGCCTTTCC
GTGGAACCAACACATTTGATGTATTGAAAT	TATTTCTGATTCCAGCTTGCTTCGGCTGGAAAGT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCCATAGACTTTTTTAATAGCTTCATAAATAAC
GTGGAACCAACACATTTGATGTATTGAAAT	CATCACCGCAGGCCAATTTCCAGGCTGTCTGTCAT
GTGGAACCAACACATTTGATGTATTGAAAT	ACCGTTACTCCAATCCTGGCGAGGTAGTATATGATC
GTGGAACCAACACATTTGATGTATTGAAAT	CTGGTTCACTCTGTAAATAGCGGTAAACTCTGTGTA
GTGGAACCAACACATTTGATGTATTGAAAT	CTACCCCCGCCCCCTCTCGTCTAACTCAGCTAAGGC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTAATGCCCGAGCACTGGCCGCCCCGCGTTCCCG
GTGGAACCAACACATTTGATGTATTGAAAT	ATAGCACGATCAAATACCCACAGGCCGAGGTTATA
GTGGAACCAACACATTTGATGTATTGAAAT	CTGCCTATTCGGGAGATTTACCGTATTTGGGGAAGA
GTGGAACCAACACATTTGATGTATTGAAAT	AACAACGTCGGCCCAAAGTCACACCTGTCTATAGC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTCGAAGAATAGTTTAATAGCCTGGATGTTCCCA
GTGGAACCAACACATTTGATGTATTGAAAT	CAGAATTAAGTGGGGCGTGTTTGAGAAGTTGGAGTT
GTGGAACCAACACATTTGATGTATTGAAAT	TGTGAAGATTATTAACCTGATTGGTTGTGTCGATG
GTGGAACCAACACATTTGATGTATTGAAAT	GTGGGGGGATGAACACCTGCTTGCCGATGCCCTG
GTGGAACCAACACATTTGATGTATTGAAAT	AAAAATTGGAGGTGCGGTAAATGTTAAAAGTGGTTAC
GTGGAACCAACACATTTGATGTATTGAAAT	AACTCCAAAACAAGGAAATGACAGGCAAGCAATTCTC
GTGGAACCAACACATTTGATGTATTGAAAT	CGAGAATGTACCAGATGAATTTATTGTGCAGGTAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGCTCAACCACTGGTAACGTGACCGGTATTTTTGAT
GTGGAACCAACACATTTGATGTATTGAAAT	TCGTAACGATGACACCCAGTGGCTCGGTCATGTCCAC
GTGGAACCAACACATTTGATGTATTGAAAT	ACCAGCAGAAGGCGGACATATCAAACCAGCGTGAG
GTGGAACCAACACATTTGATGTATTGAAAT	AAATCAAGGCGTTACTACTATGATTATGAAGCCATT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGGGCAGAAACACCCAATAAATCCAAAGGCAGGC
GTGGAACCAACAAATTTGATGTATTGAAAT	AACATAAGGTTTATGTGATGGGAGGTGAGAAAATGT
GTGGAACCAACACATTTGATGTATTGAAAT	TAAAACAAGCCCGACGGTTTGTCAGGTGGGAAGTTT
GTGGAACCAACACATTTGATGTATTGAAAT	ATTCAATATCCCCTTACCTTACCGTCCATCCAAGCA
GTGGAACCAACACATTTGATGTATTGAAAT	CTATAAAATAGGGAGGATCAGTATGTTTAACATTGA
GTGGAACCAACACATTTGATGTATTGAAAT	GAGTACATCCGCGTGGCCCTGGTGGGCTGCACTCTG
GTGGAACCAACACATTTGATGTATTGAAAT	GTTGCCGAATATAGCGCAAGTATTAGTAAGGTATA
GTGGAACCAACACATTTGATGTATTGAAAT	TGGACAGGATGATGTTGATTGTGGCGATGACCAGTGC
GTGGAACCAACACATTTGATGTATTGAAAT	CCTAGTTGATGGAAAGATCGTTCCATTCAACTCTAAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATGGACTACAAAATTTTCTACTACGAGATTTCAC
GTGGAACCAACACATTTGATGTATTGAAAT	TAAATAAGGCCTTCGGCAACTACCCAAAGGCCAGTA
GTGGAACCAACACATTTGATGTATTGAAAT	CCGAAATTAATGCTGTTATGTCTCCCAAAATGTTT
GTGGAACCAACACATTTGATGTATTGAAAT	AACTGATTCTATGGTATCTCTTAATGTGGATCTTGC
GTGGAACCAACACATTTGATGTATTGAAAT	GGCGATAGGCAAATGTGTACATTTTGTGAAAATCGA
GTGGAACCAACACATTTGATGTATTGAAAT	AGAAGTGGGAGCAGCATAATTACCTAGTGGAGAAA
GTGGAACCAACACATTTGATGTATTGAAAT	CTGTCGTACTTGGTTCTTGCCATTTCTGAACCTTAT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGCAGGTTAAATCCTCAACTCCGGAAGGTACTGAC
GTGGAACCAACACATTTGATGTATTGAAAT	ATTTCAACCTGGTTATTACCGATTGTCGATATCTAA
GTGGAACCAACACATTTGATGTATTGAAAT	CCACCTTTCAGCCGACTGGAGGATATCGCTAATTA
GTGGAACCAACACATTTGATGTATTGAAAT	TACCATAGCCATCGCATGTCTGTTAAATGGTGATTAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTGCTAGTAAAAGCGAATGCGCTTTTATTTTTTACAT
GTGGAACCAACACATTTGATGTATTGAAAT	AGTTCACGTATTCCAGATTTCACACGGGTCATTTT
GTGGAACCAACACATTTGATGTATTGAAAT	AGTAGATTGGCATGAGCTTCGGGCCTGTGACTATGG
GTGGAACCAACACATTTGATGTATTGAAAT	ATATCTGGGCGTCTGTCTGCAAAATGAGGGCGAC
GTGGAACCAACACATTTGATGTATTGAAAT	TTTATTGCATTTTTTATTATCAGTGTTTTCATAATT
GTGGAACCAACACATTTGATGTATTGAAAT	AAATATCCGGCCGCATCCAGAACATCTTCAACGCCC
GTGGAACCAACACATTTGATGTATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_006523432.1\|520992_521691_+\|CRISPR-associated-protein-Cas6	unknown	unknown	gnl\|CDD\|273848
NC_021184.1\|WP_041285143.1\|535387_536647_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NC_021184.1\|WP_015617907.1\|536639_537440_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|132060
NC_021184.1\|WP_006523431.1\|521695_523501_+\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	unknown
NC_021184.1\|WP_006524054.1\|538827_538998_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006523429.1\|524429_525170_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_021184.1\|WP_015617906.1\|528139_529147_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NC_021184.1\|WP_006523428.1\|525254_527639_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271183
NC_021184.1\|WP_006523421.1\|534720_535284_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006523425.1\|529143_529428_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	unknown	unknown	gnl\|CDD\|379963
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271193
NC_021184.1\|WP_041284742.1\|527635_528124_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_021184.1\|WP_006523430.1\|523484_524417_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_021184.1\|WP_041284741.1\|518553_518916_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|310261
NC_021184.1\|WP_006523434.1\|519723_519999_+\|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379534

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_006523432.1\|520992_521691_+\|CRISPR-associated-protein-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	3.67952e-10
NC_021184.1\|WP_041285143.1\|535387_536647_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.36106e-23
NC_021184.1\|WP_015617907.1\|536639_537440_+\|AAA-family-ATPase	gnl\|CDD\|132060	TIGR03015, pepcterm_ATPase, putative secretion ATPase, PEP-CTERM locus subfamily. Members of this protein are marked as probable ATPases by the nucleotide binding P-loop motif GXXGXGKTT, a motif DEAQ similar to the DEAD/H box of helicases, and extensive homology to ATPases of MSHA-type pilus systems and to GspA proteins associated with type II protein secretion systems. [Protein fate, Protein and peptide secretion and trafficking].	3.24053e-37
NC_021184.1\|WP_006523429.1\|524429_525170_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.26229e-44
NC_021184.1\|WP_015617906.1\|528139_529147_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.6962e-140
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	6.30561e-118
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	7.69041e-102
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	2.79612e-81
NC_021184.1\|WP_006523428.1\|525254_527639_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	1.46758e-27
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	gnl\|CDD\|271183	cd01182, INT_RitC_C_like, C-terminal catalytic domain of recombinase RitC, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	7.52778e-85
NC_021184.1\|WP_006523425.1\|529143_529428_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.7196e-25
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	gnl\|CDD\|379963	pfam17295, DUF5348, Domain of unknown function (DUF5348).	7.17066e-15
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	gnl\|CDD\|271193	cd01193, INT_IntI_C, Integron integrase and similar protiens, C-terminal catalytic domain. Integron integrases mediate site-specific DNA recombination between a proximal primary site (attI) and a secondary target site (attC) found within mobile gene cassettes encoding resistance or virulence factors. Unlike other site specific recombinases, the attC sites lack sequence conservation. Integron integrase exhibits broader DNA specificity by recognizing the non-conserved attC sites. The structure shows that DNA target site recognition are not dependent on canonical DNA but on the position of two flipped-out bases that interact in cis and in trans with the integrase. Integron-integrases are present in many natural occurring mobile elements, including transposons and conjugative plasmids. Vibrio, Shewanella, Xanthomonas, and Pseudomonas species harbor chromosomal super-integrons. All integron-integrases carry large inserts unlike the TnpF ermF-like proteins also seen in this group.	1.48872e-62
NC_021184.1\|WP_041284742.1\|527635_528124_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.43351e-53
NC_021184.1\|WP_006523430.1\|523484_524417_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.52974e-36
NC_021184.1\|WP_041284741.1\|518553_518916_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|310261	pfam05534, HicB, HicB family. This family consists of several bacterial HicB related proteins. The function of HicB is unknown although it is thought to be involved in pilus formation. It has been speculated that HicB performs a function antagonistic to that of pili and yet is necessary for invasion of certain niches.	5.26639e-13
NC_021184.1\|WP_006523434.1\|519723_519999_+\|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein	gnl\|CDD\|379534	pfam14278, TetR_C_8, Transcriptional regulator C-terminal region. This domain is a tetracycline repressor, domain 2, or C-terminus.	3.04456e-17

>NC_021184.1|WP_006523425.1|529143_529428_+|CRISPR-associated-endonuclease-Cas2
MNKPNYNYAIVFYDVGEKRVAKIFKICKQYLKHYQKSVFRGHITPGNYLELKGKLKKAIDPDHDFVTFIQTISESSFHEESIGNTGVNPESIII
>NC_021184.1|WP_015617906.1|528139_529147_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MGKSSDTRYIFSTGDLYQKDFSIVFRKEDGNFYLPIKDTRELYCFNEITLSTKLLQLLAKVGIVVHFFGYYENYIGTFYPKEQLLSGRLTVAQALAYEQNRLKIAGPIVKGIAKNIHFVLYHYYRHGKSELKDYLDWLRKDVSRLADAVGDIKQLLRIEGEIWARFYQTFRLILPESFAMNKRVKRPPDNPINALISFGNTLLYTKTITEIYHTHLNQTISFLHEPAERRFSLSLDLSEVFKPVLVYKTIFDCVNNRKITVEKHFDKKLNYALLNEIGRKTFIEAFEERLNQTFEHQTLKRRCSYKQAIRLDGYKLIKHILEGKNFVPFCMEDKK
>NC_021184.1|WP_041284742.1|527635_528124_+|CRISPR-associated-protein-Cas4
MMLTGTVVNYYTHCQRQCWLFYHNLNLEDNSEDVRIGKVLHELKKQGKEEIALDGIKLDKLTAEYVTEIKKSDADLAAAKAQLEFYLVVLHDKGIIRKGRLECLEKNKQSKSVHTLMLTEGEIEERKVQYRQIEEFLNRELPPPPIRKPICKKCAYYEYCFI
>NC_021184.1|WP_006523428.1|525254_527639_+|CRISPR-associated-helicase/endonuclease-Cas3
MKKIKLITPVLLQDARYLAHTRKTGGIRETETLLAHSELTLRYYEVYCEQKRMGEIIQRLIAACGFRGEEAQTVYLMFLYAIYLHDAGKINPRYQYEVLENASFGADRRQARNTHHALASAYIYIDHMYKILLNNPSEAVQKCLAAFAYCICRHHGKLDNGHDFSNLETWDEKYYQSELDGSIFEYVRYYMQESGVVEQPLSFYILCRLLYALITGCDYCATQEFMTGHSMRPAVIQNGGENLKRCYDGSAICRSIRQYQKDPAAFSGNPINALRNQLFLETEQNLLARRDAHIYYLEAPTGAGKTNMAINLALRVLEMDSKINNVFYIFPFNTLVEQTRKTMHPFFGDQLVVINSITPVVMGRDDRKDNYEVAWLDHIFNNYPIVLTSHINFFNALFGCGREQCFPLLKLCNSVVILDEIQSYKNSIWREIISFLQSYAQQLHIKIIMMSATLPQLDQMLRTVDAQFATLVEDPQRYYRHPLFQGRVRLDFSLLEKGKITLEELKEEVLRFQGKRVLVEFIKKRTAREFYELCKEACNVVLLTGDDNVARRDQVIRRIDSGEKLILIATQVIEAGVNIDMETGFKDISLPDAEEQFLGRINRSCLNVGGAVAYFFDLDDASFIYRGDARLSYSIQDPAIRQNLQKKQFGEIYVRVFSDLIAQTSKANEKNLANLDENCAQFNCKKIEEQMRLIDRNWQLFIPYVWEDLDGYQVWEEFKALSGNREMGYAQRMVEYSRLALKMSYFTFSVFRDKIPAGAEEYGGYYFIDGGERFVEDGVLDREALEKYYGGIFL
>NC_021184.1|WP_006523429.1|524429_525170_+|type-I-B-CRISPR-associated-protein-Cas5
MKSLCFTLSGPAACFRQPDVNTQVYFTYNNIHKVALLGLLGAVLGLSGYRNAKLHGQEERVFPEFYEVLSSLLVSVVPNGKNGYFTKKIQYFNNSVGYASKEKGGNLQVREQWLENPSWTIFLAQHNLDDVVWDKLCSNLLQGQCVYIPYLGRNDFPAQIEDVLMVELSPSRQSRIDSLFLYEGDLKALDGGGPSRYLFVETAPIGLVPNYNFYEFRRYVFTNGTIPEAALPSFLYTDGDRQYCFY
>NC_021184.1|WP_006523430.1|523484_524417_+|type-I-CRISPR-associated-protein-Cas7
MKKENRVYGILAVGAYMANFNADLSGYPKTTTDNHIFGSDKALKYPMKRMWQMQGEPVLYIKSMKSMQTDKEGEKIQPRDLNERYTYLFGNLDEKTSSKEVLSRLFSAIDVMNFGATFAEKKQNISITGAVQINQGRNLFEDTHVLTQEILSPFRNSNEKSEEKLASSMGTKIVTDEAHYVYSFSVNPANYNVFIELADGFEGYTSEAYEKFKWAARVATTAFNTNSKSGCENELALFIELKEDSQLFLANLDRYVTVRKKGDHILYDLSKLAKVLEPRQGEIQSVELYCNLDTVEVDYGSLPCSVQSIY
>NC_021184.1|WP_006523431.1|521695_523501_+|hypothetical-protein
MLKELLNEFTSHQTQYPEFDVDTMVVQNYRLKPGLYIRLNEYGGMDEFYVTKKMVWPENDPLLEWFKQADFASSLIEMNKPVDPKKKIHSNNLFTLFCKHDTFGVGGVQSELREHIDRYFKALLGVRDKESAEILKTAGYEPLQAETIEKSKTRFLSSLETVGEMINQHNIKDNYYIKLFLDAKLNDYIYESGRYLLPKIFNSNSYNIKSNDQVLGLSNVNMGMNAKKPYLEHKTTAFKVPYRITAEEGVLLRKLFLWLNGQEREGKSLYTGYFPIGKHDHPGLFAVAGEMKVRRSAVYVHLDRGMDLTVDDYDFLPSFKDRMDKPVVFENYLDVSNYPGGTLNMLSAVEVHINTYLYGGQLVRNYYVEKIQVTDKLPKVLVDQIMLTREALHSWLRKGNDYPMQNCVDKATMGVLLARLQNLGYISALAYALNVRLALLNYFREGENDMGYAIEEAYIALKEKVTKTDSKKEHVACQSAMEFYLAMGQLLYYYFSRSKAQKLHYDVLWRGIASAKSVEDVKREHRKHFQKYAYDIDIDYSRFNNMLSIVSSYEPEEEEPINLDALFYGFAANSIIYYKDKDKDTKGNENNKEAAENEKGK
>NC_021184.1|WP_006523432.1|520992_521691_+|CRISPR-associated-protein-Cas6
MTHYYYEILSTVRFNQDVFASEVQSALAHLTNNSMIFDEQLKELHHQNTFKHYVFCAPYPLEADRIYRKGRMYCFHLRTLSLEFALKMKKYLPKAKGTVKVISTELNNYIKKPITELVTLTPIICTYNNRCWLPENGLGLLSERIHVNALKKCKALDASFTAPEELFFEHIEMLNKKPIVTSYKGKGAILLGHKVRLRIKPYPWAQQLAFIALAVGLLEKNGLGFGYCIAGR
>NC_021184.1|WP_006523434.1|519723_519999_+|TetR/AcrR-family-transcriptional-regulator-C-terminal-domain-containing-protein
MYLYSVINELLIGVINEISCNMKVKEGYKKFIANFYTLAFNGLVIQWMKGGMKENPTFATSTFLRILAMTSSCSINCSPSAICFSATSNLD
>NC_021184.1|WP_041284741.1|518553_518916_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MMKNLDYYLNIDFEIKLKKLSEDEGGGWLAEIPLLPGCMSDGETPEEAVNNLNQAKRDWIETCLELGRSVPEPREEYSGQLRIRIPKSLHRTLAERAKEENISLNQYISYQLSRGIGYKR
>NC_021184.1|WP_006523421.1|534720_535284_+|hypothetical-protein
MIYYHNFLVDVAKYAELGKANEFPELDCCPMCRAKIRLKRHGFYKRNAIESGAEIYRIPICRLICPDCGKTISILPTFLLPYFQHTMDFIIRILLTSWIAYRLLCSRQLRRFYEKRAYGKLTEIELFIREQGNRKALPDALKEKAIKMLQMIQALGKATFVRRWWGHRISSFMAHSLYHGARVVKTI
>NC_021184.1|WP_041285143.1|535387_536647_+|DDE-type-integrase/transposase/recombinase
MDESIREKIALFRYGIIAPLLNEQVDREAYLAEQSAKKHEVPHYGERTYAAKTILEWLLLYRRQGFDGLKPARRSDRGQLRTLSSDQQDYVLALRKERLWMPVTVFYDQLIEQGEVFPKEVSYSTIHRFLKKQGLLGKETPKTPERKRFAHAKVNALWQTDASEGPRLRIGGKVVRTYLIAFIDDCSRLVPYAMFVPSEKFDGLRMVMKEALIRRGIPKMVYTDNGKIFRSQIMQFACASLGIQLLHTQAYDPQAKGKIERMFRTCKTRFYTLLKASPVSSLDELNERFWRWLEEDYHRKPHASLDGRMPLEVYLSQVDSIRTVDDPLALDSVFLKRAFRKVKHDATFSLENRLYEVPDIFAGQKVELRYDESGVHLYEDGKVVAQAVEVSFHDNAHVKRQRSSLSFKELHAKEGGDGV
>NC_021184.1|WP_015617907.1|536639_537440_+|AAA-family-ATPase
MYKAFYSLAAAPFSKELKVSDAYVSTPHQEALGCLNYMKQVRGMGLFVGEPGAGKTYALRVFTDSLNKSLYKVVYFPLSTGSVNDFYRGLAFGLGEEPKNRKVDLFRQIQQTITVLFHERKVTPVFILDEMQMAKDVFLSDLNLLFNFQMDSHNPFILLLCGLPYLRDRMALNHNRPLAQRLLLSHHIEPLDKEEVKGYVLHHMTLAGAKHPIFTDAAFEAIAACTQGYPRLINKLGTHALLHGYMRKAEQIDAETIRIAAQENGM
>NC_021184.1|WP_083939749.1|537447_537684_+|DUF5348-domain-containing-protein
MIPRKRDGRILYNVKTDRWDVWDVYSKPVALHCGECFEIKLGDHFLSCRIEMDSEWVIYLSNTRFHLHPKVSYWIRVE
>NC_021184.1|WP_006524054.1|538827_538998_+|hypothetical-protein
MCRLGKVAIQTEAQNYPEAYGVDVADRWKERLRSYPGRSHGREEMNFKSRLKQDLS
>NC_021184.1|WP_006524053.1|539074_539830_+|RNA-directed-DNA-polymerase
MNVTKKGAKCSQLPTGGSRMEGSPQKNSAEHKGYAGAHNPLRITENNITNADMSKERLLEEIVDRSNMNKAYKRVKSNKGAHGIDGMGVDKLLQYLKENGGQLRQSILDGKYCPNPVRRVEIPKEDGKKKRKLGIPTVVDRVVQQAIAQVLTPICEKQFSDNSYGFRPGRSAHDAIRKCRDNISEGYNYVVDMDLEKYFDTVNQSKLVEVLSRTIKDGRVISLIHKYLRAGVIIKHKFEETKVGVPQGGLC
>NC_021184.1|WP_006524052.1|540009_540891_+|site-specific-integrase
MENKEQVLLRMKKDILLRGLSKNTLESYTLNARIFLEYCNRPVEQLNEYDIRNFLWYLINEKKASPGTVNTYSAAIRFLFAVTLNRTLNYLQIPRQKKRKTFPEVLTREEVFSIIESCKNIKHKAMLMVVYSSGLRVSEAAALKIQHIDSKNMRIFVEDGKGGKDRYTVLSATCLSVLREYWKRYRPKNPEGWLFLGTYNVSHITTRGIAFAFNEAVKRANITKNVSIHSLRHSFATHLLEDGATLLQIKELLGHTSIKSTTIYVHLANVTSDIKSPLDNSPAYRSLEVPSNA
>NC_021184.1|WP_006524051.1|540883_542011_+|IS91-family-transposase
MLELQDIFAQHGKTYRLNHSLLLNQVKVMRAIENCRTSALGGHTDECDECGFIRISYNSCRNRHCPKCQTLNKERWIEARKDDLLNVGYFHVVFTVPDTLNPVAYQNQTVVYNILFKAAAETLSELAADKKYLGAQIGFTEILHTWGQNLMYHPHIHCIVPGGGLNSCGKWVNSRKKFFIPVKVLSRKFRGKFLYYLKQAKLEFYSLISYLQDDGMFNNFISSLYQKEWIVYCKPPFKNAGCVVEYLGRYTHRVAISNSRILKLEDGVVTFKWRDYKDNNKQKNMNLTADEFIRRFLIHVLPNGFTKIRHYGLLSPRNKATKLKLCKKLTNTSINDKPKVKLSTLDFLKKLTGRDFSICPCCGIGHLSRASPGKM
>NC_021184.1|WP_006521022.1|542552_543770_-|IS256-like-element-ISDgi1-family-transposase
MQAMQDKTIKELAKDCRTVEDVHEMLKNLFKDTLQQIFEAEIEEHLGYKKHSIEGNNTGNSRNGYNKKTIQTKFGKTEVEIPRDRNGEFEPRIIGKYEKTSNQLEDQIIAMYAKGMSTRDIEDHMRDIYGIDVSPTMVSKITDKILPMIAEWQSRTLDRIYPIVFLDAIHFKVRKDNRIINKAAYSVLALNMAGQKEILGIWIGENESASFWLGVCNDLKSRGVQDILIACKDGLSGFSEAINTVFPKTEIQLCIIHQIRNSLKYVPYKEQKELMADLKQVYQALTLEEAELAFEIFKENWGKRHPIIIRSWEKNWLELTAYFKYPYEIRKMIYTTNIIEGYHRQLRKVTKTKTAYPTDDALKKIIYLATVEAAKKWTMPVKDWKNCISQFAIYFGDRIESEMAI
>NC_021184.1|WP_006524050.1|543859_544873_-|site-specific-integrase
MQSTDFAEHLTQFLTVYLPAQKNASKNTIASYRDTFKLLLQYCQEQQDIPAEKLTMRMLTHDLVADFLGWLETNRNCSISTRNQRLTAIHSFFRYAQYEEPMGLANFQKVLSIPVKKAPKSDVPHLNTDAMQLLLSQPDKSTPKGRRDLTLLSVLYDSGCRVQELVDLKVRDVILTDPSVLVLTGKGNKTRRVPLMKNTATLLDSYIHENKLEKPWKSDYLLFTNKQHNKLTKEGVSYIISKYVTSARQVSSIVPERVTPHMFRHSKSVHLLQAGVNLIYIRDFLGHVDIKTTEVYAKCDTELKRRAIENAYPELVDSDLPDWSQNTSLLNWLSSLK

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Crispr_ID: NC_021184_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_3

537907-538658

TypeI-B

Consensus_repeat	Method
GTGGAACCAACACATTTGATGTATTGAAAT	PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	CRT

11 spacers

cas2,cas1,cas4,cas3,cas5,cas7b,RT

The CRISPR arrays of NC_021184_3

>merge|NC_021184|3|537907-538658|PILER-CR,CRISPRCasFinder,CRT
GTGGAACCAACACATTTGATGTATTGAAATCGTCAATGGGAGCTATCGGCTCAACCGGCTCATTTTGTGGAACCAACACATTTGATGTATTGAAATTGTTCAAAAACAACCTGATCAACTGACTGTCTGCCAGTGGAACCAACACATTTGATGTATTGAAATACCCAAATGATTACCTGCTTAAACTGGTTCAGCCATGTGGAACCAACACATTTGATGTATTGAAATATTTATACAAGAGAGTGGGTTATTACTAGGTCCTTGGTGGAACCAACACATTTGATGTATTGAAATAGCAGCTAATGAATTTGCAAATCGGCCAGCGCTGACGTGGAACCAACACATTTGATGTATTGAAATAATATCTTGGCCCTTCTTGCCTCGCTTGCATCAAGTGGAACCAACACATTTGATGTATTGAAATTTTTGCAACGGACATAAATTGTTGCAGTCCGGTGTGGGTGGAACCAACACATTTGATGTATTGAAATACGTTACCTTGACGTGCCGCAGGTTAGTATTATTCCGTGGAACCAACACATTTGATGTATTGAAATAAATAGAACGCTTTTCCGCACTCCGGGCAGCATGGGTGGAACCAACACATTTGATGTATTGAAATTTCAAGTCTCTGGTGGAACTCCCCGAGTTTGAACGTGGAACCAACACATTTGATGTATTGAAATAGGGACACAATGCTATTCGCACGTTGCGTATTACAAGTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|3|2|537907-538658|PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	CGTCAATGGGAGCTATCGGCTCAACCGGCTCATTTT
GTGGAACCAACACATTTGATGTATTGAAAT	TGTTCAAAAACAACCTGATCAACTGACTGTCTGCCA
GTGGAACCAACACATTTGATGTATTGAAAT	ACCCAAATGATTACCTGCTTAAACTGGTTCAGCCAT
GTGGAACCAACACATTTGATGTATTGAAAT	ATTTATACAAGAGAGTGGGTTATTACTAGGTCCTTG
GTGGAACCAACACATTTGATGTATTGAAAT	AGCAGCTAATGAATTTGCAAATCGGCCAGCGCTGAC
GTGGAACCAACACATTTGATGTATTGAAAT	AATATCTTGGCCCTTCTTGCCTCGCTTGCATCAA
GTGGAACCAACACATTTGATGTATTGAAAT	TTTTGCAACGGACATAAATTGTTGCAGTCCGGTGTGG
GTGGAACCAACACATTTGATGTATTGAAAT	ACGTTACCTTGACGTGCCGCAGGTTAGTATTATTCC
GTGGAACCAACACATTTGATGTATTGAAAT	AAATAGAACGCTTTTCCGCACTCCGGGCAGCATGG
GTGGAACCAACACATTTGATGTATTGAAAT	TTCAAGTCTCTGGTGGAACTCCCCGAGTTTGAAC
GTGGAACCAACACATTTGATGTATTGAAAT	AGGGACACAATGCTATTCGCACGTTGCGTATTACAA
GTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|3|3|537907-538658|CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	CGTCAATGGGAGCTATCGGCTCAACCGGCTCATTTT
GTGGAACCAACACATTTGATGTATTGAAAT	TGTTCAAAAACAACCTGATCAACTGACTGTCTGCCA
GTGGAACCAACACATTTGATGTATTGAAAT	ACCCAAATGATTACCTGCTTAAACTGGTTCAGCCAT
GTGGAACCAACACATTTGATGTATTGAAAT	ATTTATACAAGAGAGTGGGTTATTACTAGGTCCTTG
GTGGAACCAACACATTTGATGTATTGAAAT	AGCAGCTAATGAATTTGCAAATCGGCCAGCGCTGAC
GTGGAACCAACACATTTGATGTATTGAAAT	AATATCTTGGCCCTTCTTGCCTCGCTTGCATCAA
GTGGAACCAACACATTTGATGTATTGAAAT	TTTTGCAACGGACATAAATTGTTGCAGTCCGGTGTGG
GTGGAACCAACACATTTGATGTATTGAAAT	ACGTTACCTTGACGTGCCGCAGGTTAGTATTATTCC
GTGGAACCAACACATTTGATGTATTGAAAT	AAATAGAACGCTTTTCCGCACTCCGGGCAGCATGG
GTGGAACCAACACATTTGATGTATTGAAAT	TTCAAGTCTCTGGTGGAACTCCCCGAGTTTGAAC
GTGGAACCAACACATTTGATGTATTGAAAT	AGGGACACAATGCTATTCGCACGTTGCGTATTACAA
GTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|3|2|537907-538658|CRT
GTGGAACCAACACATTTGATGTATTGAAAT	CGTCAATGGGAGCTATCGGCTCAACCGGCTCATTTT
GTGGAACCAACACATTTGATGTATTGAAAT	TGTTCAAAAACAACCTGATCAACTGACTGTCTGCCA
GTGGAACCAACACATTTGATGTATTGAAAT	ACCCAAATGATTACCTGCTTAAACTGGTTCAGCCAT
GTGGAACCAACACATTTGATGTATTGAAAT	ATTTATACAAGAGAGTGGGTTATTACTAGGTCCTTG
GTGGAACCAACACATTTGATGTATTGAAAT	AGCAGCTAATGAATTTGCAAATCGGCCAGCGCTGAC
GTGGAACCAACACATTTGATGTATTGAAAT	AATATCTTGGCCCTTCTTGCCTCGCTTGCATCAA
GTGGAACCAACACATTTGATGTATTGAAAT	TTTTGCAACGGACATAAATTGTTGCAGTCCGGTGTGG
GTGGAACCAACACATTTGATGTATTGAAAT	ACGTTACCTTGACGTGCCGCAGGTTAGTATTATTCC
GTGGAACCAACACATTTGATGTATTGAAAT	AAATAGAACGCTTTTCCGCACTCCGGGCAGCATGG
GTGGAACCAACACATTTGATGTATTGAAAT	TTCAAGTCTCTGGTGGAACTCCCCGAGTTTGAAC
GTGGAACCAACACATTTGATGTATTGAAAT	AGGGACACAATGCTATTCGCACGTTGCGTATTACAA
GTGGAACCAACACATTTGATGTATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_083940007.1\|545826_546984_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271188
NC_021184.1\|WP_041285143.1\|535387_536647_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NC_021184.1\|WP_015617907.1\|536639_537440_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|132060
NC_021184.1\|WP_157872710.1\|549080_550248_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_021184.1\|WP_006524054.1\|538827_538998_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006523429.1\|524429_525170_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_021184.1\|WP_015617906.1\|528139_529147_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_021184.1\|WP_006524044.1\|551338_551818_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_021184.1\|WP_006524049.1\|544859_545834_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271178
NC_021184.1\|WP_006523428.1\|525254_527639_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|187770
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271183
NC_021184.1\|WP_006523421.1\|534720_535284_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006523425.1\|529143_529428_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	unknown	unknown	gnl\|CDD\|379963
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271193
NC_021184.1\|WP_041284742.1\|527635_528124_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_021184.1\|WP_006523430.1\|523484_524417_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_041285143.1\|535387_536647_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.36106e-23
NC_021184.1\|WP_015617907.1\|536639_537440_+\|AAA-family-ATPase	gnl\|CDD\|132060	TIGR03015, pepcterm_ATPase, putative secretion ATPase, PEP-CTERM locus subfamily. Members of this protein are marked as probable ATPases by the nucleotide binding P-loop motif GXXGXGKTT, a motif DEAQ similar to the DEAD/H box of helicases, and extensive homology to ATPases of MSHA-type pilus systems and to GspA proteins associated with type II protein secretion systems. [Protein fate, Protein and peptide secretion and trafficking].	3.24053e-37
NC_021184.1\|WP_157872710.1\|549080_550248_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.05763e-37
NC_021184.1\|WP_006523429.1\|524429_525170_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.26229e-44
NC_021184.1\|WP_015617906.1\|528139_529147_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.6962e-140
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	6.30561e-118
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	7.69041e-102
NC_021184.1\|WP_006524044.1\|551338_551818_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.42971e-16
NC_021184.1\|WP_006524049.1\|544859_545834_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271178	cd00797, INT_RitB_C_like, C-terminal catalytic domain of recombinase RitB, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	5.58573e-67
NC_021184.1\|WP_006523428.1\|525254_527639_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|187770	cd09639, Cas3_I, CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DEAD/DEAH box helicase DNA helicase cas3'; Often but not always is fused to HD nuclease domain; signature gene for Type I.	1.46758e-27
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	gnl\|CDD\|271183	cd01182, INT_RitC_C_like, C-terminal catalytic domain of recombinase RitC, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	7.52778e-85
NC_021184.1\|WP_083940007.1\|545826_546984_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271188	cd01188, INT_RitA_C_like, C-terminal catalytic domain of recombinase RitA, a component of the recombinase trio. Recombinases RitA (also known as pAE1), RitB, and RitC are encoded by three adjacent and overlapping genes. Collectively they are known as the Recombinase in Trio (RIT). This RitA family includes various bacterial integrases and integrases from the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus H1. All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.07673e-73
NC_021184.1\|WP_006523425.1\|529143_529428_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.7196e-25
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	gnl\|CDD\|379963	pfam17295, DUF5348, Domain of unknown function (DUF5348).	7.17066e-15
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	gnl\|CDD\|271193	cd01193, INT_IntI_C, Integron integrase and similar protiens, C-terminal catalytic domain. Integron integrases mediate site-specific DNA recombination between a proximal primary site (attI) and a secondary target site (attC) found within mobile gene cassettes encoding resistance or virulence factors. Unlike other site specific recombinases, the attC sites lack sequence conservation. Integron integrase exhibits broader DNA specificity by recognizing the non-conserved attC sites. The structure shows that DNA target site recognition are not dependent on canonical DNA but on the position of two flipped-out bases that interact in cis and in trans with the integrase. Integron-integrases are present in many natural occurring mobile elements, including transposons and conjugative plasmids. Vibrio, Shewanella, Xanthomonas, and Pseudomonas species harbor chromosomal super-integrons. All integron-integrases carry large inserts unlike the TnpF ermF-like proteins also seen in this group.	1.48872e-62
NC_021184.1\|WP_041284742.1\|527635_528124_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.43351e-53
NC_021184.1\|WP_006523430.1\|523484_524417_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.52974e-36
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	2.79612e-81

>NC_021184.1|WP_083939749.1|537447_537684_+|DUF5348-domain-containing-protein
MIPRKRDGRILYNVKTDRWDVWDVYSKPVALHCGECFEIKLGDHFLSCRIEMDSEWVIYLSNTRFHLHPKVSYWIRVE
>NC_021184.1|WP_015617907.1|536639_537440_+|AAA-family-ATPase
MYKAFYSLAAAPFSKELKVSDAYVSTPHQEALGCLNYMKQVRGMGLFVGEPGAGKTYALRVFTDSLNKSLYKVVYFPLSTGSVNDFYRGLAFGLGEEPKNRKVDLFRQIQQTITVLFHERKVTPVFILDEMQMAKDVFLSDLNLLFNFQMDSHNPFILLLCGLPYLRDRMALNHNRPLAQRLLLSHHIEPLDKEEVKGYVLHHMTLAGAKHPIFTDAAFEAIAACTQGYPRLINKLGTHALLHGYMRKAEQIDAETIRIAAQENGM
>NC_021184.1|WP_041285143.1|535387_536647_+|DDE-type-integrase/transposase/recombinase
MDESIREKIALFRYGIIAPLLNEQVDREAYLAEQSAKKHEVPHYGERTYAAKTILEWLLLYRRQGFDGLKPARRSDRGQLRTLSSDQQDYVLALRKERLWMPVTVFYDQLIEQGEVFPKEVSYSTIHRFLKKQGLLGKETPKTPERKRFAHAKVNALWQTDASEGPRLRIGGKVVRTYLIAFIDDCSRLVPYAMFVPSEKFDGLRMVMKEALIRRGIPKMVYTDNGKIFRSQIMQFACASLGIQLLHTQAYDPQAKGKIERMFRTCKTRFYTLLKASPVSSLDELNERFWRWLEEDYHRKPHASLDGRMPLEVYLSQVDSIRTVDDPLALDSVFLKRAFRKVKHDATFSLENRLYEVPDIFAGQKVELRYDESGVHLYEDGKVVAQAVEVSFHDNAHVKRQRSSLSFKELHAKEGGDGV
>NC_021184.1|WP_006523421.1|534720_535284_+|hypothetical-protein
MIYYHNFLVDVAKYAELGKANEFPELDCCPMCRAKIRLKRHGFYKRNAIESGAEIYRIPICRLICPDCGKTISILPTFLLPYFQHTMDFIIRILLTSWIAYRLLCSRQLRRFYEKRAYGKLTEIELFIREQGNRKALPDALKEKAIKMLQMIQALGKATFVRRWWGHRISSFMAHSLYHGARVVKTI
>NC_021184.1|WP_006523425.1|529143_529428_+|CRISPR-associated-endonuclease-Cas2
MNKPNYNYAIVFYDVGEKRVAKIFKICKQYLKHYQKSVFRGHITPGNYLELKGKLKKAIDPDHDFVTFIQTISESSFHEESIGNTGVNPESIII
>NC_021184.1|WP_015617906.1|528139_529147_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MGKSSDTRYIFSTGDLYQKDFSIVFRKEDGNFYLPIKDTRELYCFNEITLSTKLLQLLAKVGIVVHFFGYYENYIGTFYPKEQLLSGRLTVAQALAYEQNRLKIAGPIVKGIAKNIHFVLYHYYRHGKSELKDYLDWLRKDVSRLADAVGDIKQLLRIEGEIWARFYQTFRLILPESFAMNKRVKRPPDNPINALISFGNTLLYTKTITEIYHTHLNQTISFLHEPAERRFSLSLDLSEVFKPVLVYKTIFDCVNNRKITVEKHFDKKLNYALLNEIGRKTFIEAFEERLNQTFEHQTLKRRCSYKQAIRLDGYKLIKHILEGKNFVPFCMEDKK
>NC_021184.1|WP_041284742.1|527635_528124_+|CRISPR-associated-protein-Cas4
MMLTGTVVNYYTHCQRQCWLFYHNLNLEDNSEDVRIGKVLHELKKQGKEEIALDGIKLDKLTAEYVTEIKKSDADLAAAKAQLEFYLVVLHDKGIIRKGRLECLEKNKQSKSVHTLMLTEGEIEERKVQYRQIEEFLNRELPPPPIRKPICKKCAYYEYCFI
>NC_021184.1|WP_006523428.1|525254_527639_+|CRISPR-associated-helicase/endonuclease-Cas3
MKKIKLITPVLLQDARYLAHTRKTGGIRETETLLAHSELTLRYYEVYCEQKRMGEIIQRLIAACGFRGEEAQTVYLMFLYAIYLHDAGKINPRYQYEVLENASFGADRRQARNTHHALASAYIYIDHMYKILLNNPSEAVQKCLAAFAYCICRHHGKLDNGHDFSNLETWDEKYYQSELDGSIFEYVRYYMQESGVVEQPLSFYILCRLLYALITGCDYCATQEFMTGHSMRPAVIQNGGENLKRCYDGSAICRSIRQYQKDPAAFSGNPINALRNQLFLETEQNLLARRDAHIYYLEAPTGAGKTNMAINLALRVLEMDSKINNVFYIFPFNTLVEQTRKTMHPFFGDQLVVINSITPVVMGRDDRKDNYEVAWLDHIFNNYPIVLTSHINFFNALFGCGREQCFPLLKLCNSVVILDEIQSYKNSIWREIISFLQSYAQQLHIKIIMMSATLPQLDQMLRTVDAQFATLVEDPQRYYRHPLFQGRVRLDFSLLEKGKITLEELKEEVLRFQGKRVLVEFIKKRTAREFYELCKEACNVVLLTGDDNVARRDQVIRRIDSGEKLILIATQVIEAGVNIDMETGFKDISLPDAEEQFLGRINRSCLNVGGAVAYFFDLDDASFIYRGDARLSYSIQDPAIRQNLQKKQFGEIYVRVFSDLIAQTSKANEKNLANLDENCAQFNCKKIEEQMRLIDRNWQLFIPYVWEDLDGYQVWEEFKALSGNREMGYAQRMVEYSRLALKMSYFTFSVFRDKIPAGAEEYGGYYFIDGGERFVEDGVLDREALEKYYGGIFL
>NC_021184.1|WP_006523429.1|524429_525170_+|type-I-B-CRISPR-associated-protein-Cas5
MKSLCFTLSGPAACFRQPDVNTQVYFTYNNIHKVALLGLLGAVLGLSGYRNAKLHGQEERVFPEFYEVLSSLLVSVVPNGKNGYFTKKIQYFNNSVGYASKEKGGNLQVREQWLENPSWTIFLAQHNLDDVVWDKLCSNLLQGQCVYIPYLGRNDFPAQIEDVLMVELSPSRQSRIDSLFLYEGDLKALDGGGPSRYLFVETAPIGLVPNYNFYEFRRYVFTNGTIPEAALPSFLYTDGDRQYCFY
>NC_021184.1|WP_006523430.1|523484_524417_+|type-I-CRISPR-associated-protein-Cas7
MKKENRVYGILAVGAYMANFNADLSGYPKTTTDNHIFGSDKALKYPMKRMWQMQGEPVLYIKSMKSMQTDKEGEKIQPRDLNERYTYLFGNLDEKTSSKEVLSRLFSAIDVMNFGATFAEKKQNISITGAVQINQGRNLFEDTHVLTQEILSPFRNSNEKSEEKLASSMGTKIVTDEAHYVYSFSVNPANYNVFIELADGFEGYTSEAYEKFKWAARVATTAFNTNSKSGCENELALFIELKEDSQLFLANLDRYVTVRKKGDHILYDLSKLAKVLEPRQGEIQSVELYCNLDTVEVDYGSLPCSVQSIY
>NC_021184.1|WP_006524054.1|538827_538998_+|hypothetical-protein
MCRLGKVAIQTEAQNYPEAYGVDVADRWKERLRSYPGRSHGREEMNFKSRLKQDLS
>NC_021184.1|WP_006524053.1|539074_539830_+|RNA-directed-DNA-polymerase
MNVTKKGAKCSQLPTGGSRMEGSPQKNSAEHKGYAGAHNPLRITENNITNADMSKERLLEEIVDRSNMNKAYKRVKSNKGAHGIDGMGVDKLLQYLKENGGQLRQSILDGKYCPNPVRRVEIPKEDGKKKRKLGIPTVVDRVVQQAIAQVLTPICEKQFSDNSYGFRPGRSAHDAIRKCRDNISEGYNYVVDMDLEKYFDTVNQSKLVEVLSRTIKDGRVISLIHKYLRAGVIIKHKFEETKVGVPQGGLC
>NC_021184.1|WP_006524052.1|540009_540891_+|site-specific-integrase
MENKEQVLLRMKKDILLRGLSKNTLESYTLNARIFLEYCNRPVEQLNEYDIRNFLWYLINEKKASPGTVNTYSAAIRFLFAVTLNRTLNYLQIPRQKKRKTFPEVLTREEVFSIIESCKNIKHKAMLMVVYSSGLRVSEAAALKIQHIDSKNMRIFVEDGKGGKDRYTVLSATCLSVLREYWKRYRPKNPEGWLFLGTYNVSHITTRGIAFAFNEAVKRANITKNVSIHSLRHSFATHLLEDGATLLQIKELLGHTSIKSTTIYVHLANVTSDIKSPLDNSPAYRSLEVPSNA
>NC_021184.1|WP_006524051.1|540883_542011_+|IS91-family-transposase
MLELQDIFAQHGKTYRLNHSLLLNQVKVMRAIENCRTSALGGHTDECDECGFIRISYNSCRNRHCPKCQTLNKERWIEARKDDLLNVGYFHVVFTVPDTLNPVAYQNQTVVYNILFKAAAETLSELAADKKYLGAQIGFTEILHTWGQNLMYHPHIHCIVPGGGLNSCGKWVNSRKKFFIPVKVLSRKFRGKFLYYLKQAKLEFYSLISYLQDDGMFNNFISSLYQKEWIVYCKPPFKNAGCVVEYLGRYTHRVAISNSRILKLEDGVVTFKWRDYKDNNKQKNMNLTADEFIRRFLIHVLPNGFTKIRHYGLLSPRNKATKLKLCKKLTNTSINDKPKVKLSTLDFLKKLTGRDFSICPCCGIGHLSRASPGKM
>NC_021184.1|WP_006521022.1|542552_543770_-|IS256-like-element-ISDgi1-family-transposase
MQAMQDKTIKELAKDCRTVEDVHEMLKNLFKDTLQQIFEAEIEEHLGYKKHSIEGNNTGNSRNGYNKKTIQTKFGKTEVEIPRDRNGEFEPRIIGKYEKTSNQLEDQIIAMYAKGMSTRDIEDHMRDIYGIDVSPTMVSKITDKILPMIAEWQSRTLDRIYPIVFLDAIHFKVRKDNRIINKAAYSVLALNMAGQKEILGIWIGENESASFWLGVCNDLKSRGVQDILIACKDGLSGFSEAINTVFPKTEIQLCIIHQIRNSLKYVPYKEQKELMADLKQVYQALTLEEAELAFEIFKENWGKRHPIIIRSWEKNWLELTAYFKYPYEIRKMIYTTNIIEGYHRQLRKVTKTKTAYPTDDALKKIIYLATVEAAKKWTMPVKDWKNCISQFAIYFGDRIESEMAI
>NC_021184.1|WP_006524050.1|543859_544873_-|site-specific-integrase
MQSTDFAEHLTQFLTVYLPAQKNASKNTIASYRDTFKLLLQYCQEQQDIPAEKLTMRMLTHDLVADFLGWLETNRNCSISTRNQRLTAIHSFFRYAQYEEPMGLANFQKVLSIPVKKAPKSDVPHLNTDAMQLLLSQPDKSTPKGRRDLTLLSVLYDSGCRVQELVDLKVRDVILTDPSVLVLTGKGNKTRRVPLMKNTATLLDSYIHENKLEKPWKSDYLLFTNKQHNKLTKEGVSYIISKYVTSARQVSSIVPERVTPHMFRHSKSVHLLQAGVNLIYIRDFLGHVDIKTTEVYAKCDTELKRRAIENAYPELVDSDLPDWSQNTSLLNWLSSLK
>NC_021184.1|WP_006524049.1|544859_545834_-|tyrosine-type-recombinase/integrase
MHDLSFKGPFAEYITDHISLKRAIGYKFEADAKNLMRFSIFTAEKYPDATALTREIVLDWCTKKLYEAQATQCARASTLRQLAIYMDNIGINAYILPKGYYPAEEKYIPYIFTENELLRFFSATDQCHYVSECPYRHLVMPVFFRMIYSCGLRPQEARLLKTEDVNLNDGILSIQHSKKDNSRLVPMSAALTARCRDYAIGIGDSKWFFPGLNGKPMTAGNAYHNFRRFLWKAGISHGGRGKGPRIYDFRHVYACHCLKKWVADGKDLSVYLPILKTYMGHDSFKDTAYYLRLTADVFPDITIKLEGYYPDIIPSLGGAVDAIH
>NC_021184.1|WP_083940007.1|545826_546984_-|tyrosine-type-recombinase/integrase
MSFYRRRWLKLLKFAEERGATYFSEQLGLDFLETQFHILRKDLDNTLSQRDVQDIRVVRMIGDFQLHHVVLRRYYKHHELLTDPYYVDISTDFRYHCERKEYSSVTIDHYVKQSARFMDYLLAQGIYNCSKITLPLVNGYIRTLVGYTYKTVEQNICSIRAFLRYLNDKGILNEDLASKTPMVQARKQTRIPSVWTKEELKALIGAIDRGSPKGKRDYAIILLACILGLRVTDIKQLTFSNFNWEEKKLTFTQSKTHETVTLPIPKEVGWAVIDYLQYGRPKVDSPVIFVRHMAPFLPFSEGDHLSQLIKSYMQIAHLPTLKKRRGMHSLRHTAASRMLEHDTPLEVISDILGHSNTDSTAVYLKVDISKLRECALDMPEVTPHA
>NC_021184.1|WP_157872710.1|549080_550248_-|IS3-family-transposase
MQKKQWSPEQKLQIVLEALKEERHIGEIASEYGVHVSVIHRWKKELLEGADKVFATSKSAKAAAQEKRKQEETIENLYAQVGRLTTQLDWLKKNLAVSYPVNERKAMVDWDISNSHLTIKAQAGLLSLNRTGLYWTAKKVSKHEVEIKHLIDKIHTQHPFKGSRRIVDDINNMDGVDYKVNRKRIQRYMREMGIRVIYPGPNLSKRNRAQYVYPYLLRNVKPAHPNHVWGIDITYCAMQGRWMYLVAIIDWYSRMIVGYELSDTMNKEFVIKAVKKAIETHGAPIILNSDQGSQFTSPVYINTLKEHGIKISMDGKGRALDNAIAERFWRTIKWEDIYLKNYETPRALRQGITAFMRYYNFERPHTSIGKKTPADVYYATTNLPQQSA
>NC_021184.1|WP_006524044.1|551338_551818_+|MarR-family-transcriptional-regulator
MSSNIDIYEFILDNIRKIVVPEELITLELSISRFELLALMLSEKHQTVTMSNLAQGMSVPMSTATGIVDRLVKKGLLKRGRSEEDRRVVTVSLTDNGKTLVEDLKKHFHDFLNRIRSLITKEEFDMAVQLIRKVVLGFQKSETNSDKKPGQYRRNIEIE

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Crispr_ID: NC_021184_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_4

547994-548615

Unclear

Consensus_repeat	Method
GTGGAACCAACACATTTGATGTATTGAAAT	PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	CRT

9 spacers

The CRISPR arrays of NC_021184_4

>merge|NC_021184|4|547994-548615|PILER-CR,CRISPRCasFinder,CRT
GTGGAACCAACACATTTGATGTATTGAAATTGCAGACATTGCGTTTTCATAAACCACTTTAGCGCGTGGAACCAACACATTTGATGTATTGAAATGTCTGAGCAAACATTGCCACCTGCTCAACCCTTGGGGTGGAACCAACACATTTGATGTATTGAAATCCAATACTGCATATCCTTGGCAAAGGTGAAATGGACGTGGAACCAACACATTTGATGTATTGAAATGTGGTTCGCGAACTTCTATTTAAGTGGACTTGACCAGTGGAACCAACACATTTGATGTATTGAAATAGCTAATGTAAGTGCAAAGATTGGATTAATTAGTTGTGGAACCAACACATTTGATGTATTGAAATACCGGTTAAGCAAAAAACTGAACAGGTAGTTAAGAAGGTGGAACCAACACATTTGATGTATTGAAATCCGTTTACACCGAGGTAACCGATGAAGCCAGGAAGTGTGGAACCAACACATTTGATGTATTGAAATAAACCTTGGGGATGCCAGTAGCCTACGGTGAGTTTGGTGGAACCAACACATTTGATGTATTGAAATTCCTGAGTAGAAAGTGCCTGACGTATAGGCATAATGTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|4|3|547994-548615|PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	TGCAGACATTGCGTTTTCATAAACCACTTTAGCGC
GTGGAACCAACACATTTGATGTATTGAAAT	GTCTGAGCAAACATTGCCACCTGCTCAACCCTTGGG
GTGGAACCAACACATTTGATGTATTGAAAT	CCAATACTGCATATCCTTGGCAAAGGTGAAATGGAC
GTGGAACCAACACATTTGATGTATTGAAAT	GTGGTTCGCGAACTTCTATTTAAGTGGACTTGACCA
GTGGAACCAACACATTTGATGTATTGAAAT	AGCTAATGTAAGTGCAAAGATTGGATTAATTAGTT
GTGGAACCAACACATTTGATGTATTGAAAT	ACCGGTTAAGCAAAAAACTGAACAGGTAGTTAAGAAG
GTGGAACCAACACATTTGATGTATTGAAAT	CCGTTTACACCGAGGTAACCGATGAAGCCAGGAAGT
GTGGAACCAACACATTTGATGTATTGAAAT	AAACCTTGGGGATGCCAGTAGCCTACGGTGAGTTTG
GTGGAACCAACACATTTGATGTATTGAAAT	TCCTGAGTAGAAAGTGCCTGACGTATAGGCATAAT
GTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|4|4|547994-548615|CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	TGCAGACATTGCGTTTTCATAAACCACTTTAGCGC
GTGGAACCAACACATTTGATGTATTGAAAT	GTCTGAGCAAACATTGCCACCTGCTCAACCCTTGGG
GTGGAACCAACACATTTGATGTATTGAAAT	CCAATACTGCATATCCTTGGCAAAGGTGAAATGGAC
GTGGAACCAACACATTTGATGTATTGAAAT	GTGGTTCGCGAACTTCTATTTAAGTGGACTTGACCA
GTGGAACCAACACATTTGATGTATTGAAAT	AGCTAATGTAAGTGCAAAGATTGGATTAATTAGTT
GTGGAACCAACACATTTGATGTATTGAAAT	ACCGGTTAAGCAAAAAACTGAACAGGTAGTTAAGAAG
GTGGAACCAACACATTTGATGTATTGAAAT	CCGTTTACACCGAGGTAACCGATGAAGCCAGGAAGT
GTGGAACCAACACATTTGATGTATTGAAAT	AAACCTTGGGGATGCCAGTAGCCTACGGTGAGTTTG
GTGGAACCAACACATTTGATGTATTGAAAT	TCCTGAGTAGAAAGTGCCTGACGTATAGGCATAAT
GTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|4|3|547994-548615|CRT
GTGGAACCAACACATTTGATGTATTGAAAT	TGCAGACATTGCGTTTTCATAAACCACTTTAGCGC
GTGGAACCAACACATTTGATGTATTGAAAT	GTCTGAGCAAACATTGCCACCTGCTCAACCCTTGGG
GTGGAACCAACACATTTGATGTATTGAAAT	CCAATACTGCATATCCTTGGCAAAGGTGAAATGGAC
GTGGAACCAACACATTTGATGTATTGAAAT	GTGGTTCGCGAACTTCTATTTAAGTGGACTTGACCA
GTGGAACCAACACATTTGATGTATTGAAAT	AGCTAATGTAAGTGCAAAGATTGGATTAATTAGTT
GTGGAACCAACACATTTGATGTATTGAAAT	ACCGGTTAAGCAAAAAACTGAACAGGTAGTTAAGAAG
GTGGAACCAACACATTTGATGTATTGAAAT	CCGTTTACACCGAGGTAACCGATGAAGCCAGGAAGT
GTGGAACCAACACATTTGATGTATTGAAAT	AAACCTTGGGGATGCCAGTAGCCTACGGTGAGTTTG
GTGGAACCAACACATTTGATGTATTGAAAT	TCCTGAGTAGAAAGTGCCTGACGTATAGGCATAAT
GTGGAACCAACACATTTGATGTATTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_052543919.1\|554429_554834_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|376187
NC_021184.1\|WP_083940007.1\|545826_546984_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271188
NC_021184.1\|WP_015617907.1\|536639_537440_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|132060
NC_021184.1\|WP_157872710.1\|549080_550248_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_021184.1\|WP_006524054.1\|538827_538998_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_041284745.1\|556400_557822_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_021184.1\|WP_006524039.1\|555159_555711_+\|DUF4342-domain-containing-protein	unknown	unknown	gnl\|CDD\|270543
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_021184.1\|WP_006524044.1\|551338_551818_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_021184.1\|WP_006524049.1\|544859_545834_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271178
NC_021184.1\|WP_006524043.1\|551935_553123_+\|ArsA-family-ATPase	unknown	unknown	gnl\|CDD\|349755
NC_021184.1\|WP_006524041.1\|553567_554230_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524038.1\|555730_556408_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271183
NC_021184.1\|WP_006524036.1\|558478_559138_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	unknown	unknown	gnl\|CDD\|379963
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271193
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NC_021184.1\|WP_006524042.1\|553103_553334_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_052543919.1\|554429_554834_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	8.96192e-22
NC_021184.1\|WP_083940007.1\|545826_546984_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271188	cd01188, INT_RitA_C_like, C-terminal catalytic domain of recombinase RitA, a component of the recombinase trio. Recombinases RitA (also known as pAE1), RitB, and RitC are encoded by three adjacent and overlapping genes. Collectively they are known as the Recombinase in Trio (RIT). This RitA family includes various bacterial integrases and integrases from the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus H1. All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.07673e-73
NC_021184.1\|WP_015617907.1\|536639_537440_+\|AAA-family-ATPase	gnl\|CDD\|132060	TIGR03015, pepcterm_ATPase, putative secretion ATPase, PEP-CTERM locus subfamily. Members of this protein are marked as probable ATPases by the nucleotide binding P-loop motif GXXGXGKTT, a motif DEAQ similar to the DEAD/H box of helicases, and extensive homology to ATPases of MSHA-type pilus systems and to GspA proteins associated with type II protein secretion systems. [Protein fate, Protein and peptide secretion and trafficking].	3.24053e-37
NC_021184.1\|WP_157872710.1\|549080_550248_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.05763e-37
NC_021184.1\|WP_041284745.1\|556400_557822_+\|HAMP-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.49204e-59
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	6.30561e-118
NC_021184.1\|WP_006524039.1\|555159_555711_+\|DUF4342-domain-containing-protein	gnl\|CDD\|270543	cd14360, UBA_NAC_like_bac, UBA-like domain found in uncharacterized bacteria proteins similar to eukaryotic nascent polypeptide-associated complex proteins (NAC). This subfamily contains a group of uncharacterized proteins found in bacteria. They all contain an N-terminal ubiquitin-associated (UBA) that shows high sequence similarity with that of eukaryotic nascent polypeptide-associated complex proteins (NAC) which is one of the cytosolic chaperones that contact the nascent polypeptide chains as they emerge from the ribosome and assist in post-translational processes.	7.58082e-13
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	7.69041e-102
NC_021184.1\|WP_006524044.1\|551338_551818_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.42971e-16
NC_021184.1\|WP_006524049.1\|544859_545834_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271178	cd00797, INT_RitB_C_like, C-terminal catalytic domain of recombinase RitB, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	5.58573e-67
NC_021184.1\|WP_006524043.1\|551935_553123_+\|ArsA-family-ATPase	gnl\|CDD\|349755	cd02035, ArsA, Arsenical pump-driving ATPase ArsA. ArsA ATPase functions as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents. The pump is composed of two subunits, the catalytic ArsA subunit and the membrane subunit ArsB, which are encoded by arsA and arsB genes, respectively. Arsenic efflux in bacteria is catalyzed by either ArsB alone or by ArsAB complex. The ATP-coupled pump, however, is more efficient. ArsA is composed of two homologous halves, A1 and A2, connected by a short linker sequence.	1.39851e-103
NC_021184.1\|WP_006524038.1\|555730_556408_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.41871e-84
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	gnl\|CDD\|271183	cd01182, INT_RitC_C_like, C-terminal catalytic domain of recombinase RitC, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	7.52778e-85
NC_021184.1\|WP_006524036.1\|558478_559138_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	8.74076e-72
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	gnl\|CDD\|379963	pfam17295, DUF5348, Domain of unknown function (DUF5348).	7.17066e-15
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	gnl\|CDD\|271193	cd01193, INT_IntI_C, Integron integrase and similar protiens, C-terminal catalytic domain. Integron integrases mediate site-specific DNA recombination between a proximal primary site (attI) and a secondary target site (attC) found within mobile gene cassettes encoding resistance or virulence factors. Unlike other site specific recombinases, the attC sites lack sequence conservation. Integron integrase exhibits broader DNA specificity by recognizing the non-conserved attC sites. The structure shows that DNA target site recognition are not dependent on canonical DNA but on the position of two flipped-out bases that interact in cis and in trans with the integrase. Integron-integrases are present in many natural occurring mobile elements, including transposons and conjugative plasmids. Vibrio, Shewanella, Xanthomonas, and Pseudomonas species harbor chromosomal super-integrons. All integron-integrases carry large inserts unlike the TnpF ermF-like proteins also seen in this group.	1.48872e-62
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	2.79612e-81

>NC_021184.1|WP_083940007.1|545826_546984_-|tyrosine-type-recombinase/integrase
MSFYRRRWLKLLKFAEERGATYFSEQLGLDFLETQFHILRKDLDNTLSQRDVQDIRVVRMIGDFQLHHVVLRRYYKHHELLTDPYYVDISTDFRYHCERKEYSSVTIDHYVKQSARFMDYLLAQGIYNCSKITLPLVNGYIRTLVGYTYKTVEQNICSIRAFLRYLNDKGILNEDLASKTPMVQARKQTRIPSVWTKEELKALIGAIDRGSPKGKRDYAIILLACILGLRVTDIKQLTFSNFNWEEKKLTFTQSKTHETVTLPIPKEVGWAVIDYLQYGRPKVDSPVIFVRHMAPFLPFSEGDHLSQLIKSYMQIAHLPTLKKRRGMHSLRHTAASRMLEHDTPLEVISDILGHSNTDSTAVYLKVDISKLRECALDMPEVTPHA
>NC_021184.1|WP_006524049.1|544859_545834_-|tyrosine-type-recombinase/integrase
MHDLSFKGPFAEYITDHISLKRAIGYKFEADAKNLMRFSIFTAEKYPDATALTREIVLDWCTKKLYEAQATQCARASTLRQLAIYMDNIGINAYILPKGYYPAEEKYIPYIFTENELLRFFSATDQCHYVSECPYRHLVMPVFFRMIYSCGLRPQEARLLKTEDVNLNDGILSIQHSKKDNSRLVPMSAALTARCRDYAIGIGDSKWFFPGLNGKPMTAGNAYHNFRRFLWKAGISHGGRGKGPRIYDFRHVYACHCLKKWVADGKDLSVYLPILKTYMGHDSFKDTAYYLRLTADVFPDITIKLEGYYPDIIPSLGGAVDAIH
>NC_021184.1|WP_006524050.1|543859_544873_-|site-specific-integrase
MQSTDFAEHLTQFLTVYLPAQKNASKNTIASYRDTFKLLLQYCQEQQDIPAEKLTMRMLTHDLVADFLGWLETNRNCSISTRNQRLTAIHSFFRYAQYEEPMGLANFQKVLSIPVKKAPKSDVPHLNTDAMQLLLSQPDKSTPKGRRDLTLLSVLYDSGCRVQELVDLKVRDVILTDPSVLVLTGKGNKTRRVPLMKNTATLLDSYIHENKLEKPWKSDYLLFTNKQHNKLTKEGVSYIISKYVTSARQVSSIVPERVTPHMFRHSKSVHLLQAGVNLIYIRDFLGHVDIKTTEVYAKCDTELKRRAIENAYPELVDSDLPDWSQNTSLLNWLSSLK
>NC_021184.1|WP_006521022.1|542552_543770_-|IS256-like-element-ISDgi1-family-transposase
MQAMQDKTIKELAKDCRTVEDVHEMLKNLFKDTLQQIFEAEIEEHLGYKKHSIEGNNTGNSRNGYNKKTIQTKFGKTEVEIPRDRNGEFEPRIIGKYEKTSNQLEDQIIAMYAKGMSTRDIEDHMRDIYGIDVSPTMVSKITDKILPMIAEWQSRTLDRIYPIVFLDAIHFKVRKDNRIINKAAYSVLALNMAGQKEILGIWIGENESASFWLGVCNDLKSRGVQDILIACKDGLSGFSEAINTVFPKTEIQLCIIHQIRNSLKYVPYKEQKELMADLKQVYQALTLEEAELAFEIFKENWGKRHPIIIRSWEKNWLELTAYFKYPYEIRKMIYTTNIIEGYHRQLRKVTKTKTAYPTDDALKKIIYLATVEAAKKWTMPVKDWKNCISQFAIYFGDRIESEMAI
>NC_021184.1|WP_006524051.1|540883_542011_+|IS91-family-transposase
MLELQDIFAQHGKTYRLNHSLLLNQVKVMRAIENCRTSALGGHTDECDECGFIRISYNSCRNRHCPKCQTLNKERWIEARKDDLLNVGYFHVVFTVPDTLNPVAYQNQTVVYNILFKAAAETLSELAADKKYLGAQIGFTEILHTWGQNLMYHPHIHCIVPGGGLNSCGKWVNSRKKFFIPVKVLSRKFRGKFLYYLKQAKLEFYSLISYLQDDGMFNNFISSLYQKEWIVYCKPPFKNAGCVVEYLGRYTHRVAISNSRILKLEDGVVTFKWRDYKDNNKQKNMNLTADEFIRRFLIHVLPNGFTKIRHYGLLSPRNKATKLKLCKKLTNTSINDKPKVKLSTLDFLKKLTGRDFSICPCCGIGHLSRASPGKM
>NC_021184.1|WP_006524052.1|540009_540891_+|site-specific-integrase
MENKEQVLLRMKKDILLRGLSKNTLESYTLNARIFLEYCNRPVEQLNEYDIRNFLWYLINEKKASPGTVNTYSAAIRFLFAVTLNRTLNYLQIPRQKKRKTFPEVLTREEVFSIIESCKNIKHKAMLMVVYSSGLRVSEAAALKIQHIDSKNMRIFVEDGKGGKDRYTVLSATCLSVLREYWKRYRPKNPEGWLFLGTYNVSHITTRGIAFAFNEAVKRANITKNVSIHSLRHSFATHLLEDGATLLQIKELLGHTSIKSTTIYVHLANVTSDIKSPLDNSPAYRSLEVPSNA
>NC_021184.1|WP_006524053.1|539074_539830_+|RNA-directed-DNA-polymerase
MNVTKKGAKCSQLPTGGSRMEGSPQKNSAEHKGYAGAHNPLRITENNITNADMSKERLLEEIVDRSNMNKAYKRVKSNKGAHGIDGMGVDKLLQYLKENGGQLRQSILDGKYCPNPVRRVEIPKEDGKKKRKLGIPTVVDRVVQQAIAQVLTPICEKQFSDNSYGFRPGRSAHDAIRKCRDNISEGYNYVVDMDLEKYFDTVNQSKLVEVLSRTIKDGRVISLIHKYLRAGVIIKHKFEETKVGVPQGGLC
>NC_021184.1|WP_006524054.1|538827_538998_+|hypothetical-protein
MCRLGKVAIQTEAQNYPEAYGVDVADRWKERLRSYPGRSHGREEMNFKSRLKQDLS
>NC_021184.1|WP_083939749.1|537447_537684_+|DUF5348-domain-containing-protein
MIPRKRDGRILYNVKTDRWDVWDVYSKPVALHCGECFEIKLGDHFLSCRIEMDSEWVIYLSNTRFHLHPKVSYWIRVE
>NC_021184.1|WP_015617907.1|536639_537440_+|AAA-family-ATPase
MYKAFYSLAAAPFSKELKVSDAYVSTPHQEALGCLNYMKQVRGMGLFVGEPGAGKTYALRVFTDSLNKSLYKVVYFPLSTGSVNDFYRGLAFGLGEEPKNRKVDLFRQIQQTITVLFHERKVTPVFILDEMQMAKDVFLSDLNLLFNFQMDSHNPFILLLCGLPYLRDRMALNHNRPLAQRLLLSHHIEPLDKEEVKGYVLHHMTLAGAKHPIFTDAAFEAIAACTQGYPRLINKLGTHALLHGYMRKAEQIDAETIRIAAQENGM
>NC_021184.1|WP_157872710.1|549080_550248_-|IS3-family-transposase
MQKKQWSPEQKLQIVLEALKEERHIGEIASEYGVHVSVIHRWKKELLEGADKVFATSKSAKAAAQEKRKQEETIENLYAQVGRLTTQLDWLKKNLAVSYPVNERKAMVDWDISNSHLTIKAQAGLLSLNRTGLYWTAKKVSKHEVEIKHLIDKIHTQHPFKGSRRIVDDINNMDGVDYKVNRKRIQRYMREMGIRVIYPGPNLSKRNRAQYVYPYLLRNVKPAHPNHVWGIDITYCAMQGRWMYLVAIIDWYSRMIVGYELSDTMNKEFVIKAVKKAIETHGAPIILNSDQGSQFTSPVYINTLKEHGIKISMDGKGRALDNAIAERFWRTIKWEDIYLKNYETPRALRQGITAFMRYYNFERPHTSIGKKTPADVYYATTNLPQQSA
>NC_021184.1|WP_006524044.1|551338_551818_+|MarR-family-transcriptional-regulator
MSSNIDIYEFILDNIRKIVVPEELITLELSISRFELLALMLSEKHQTVTMSNLAQGMSVPMSTATGIVDRLVKKGLLKRGRSEEDRRVVTVSLTDNGKTLVEDLKKHFHDFLNRIRSLITKEEFDMAVQLIRKVVLGFQKSETNSDKKPGQYRRNIEIE
>NC_021184.1|WP_006524043.1|551935_553123_+|ArsA-family-ATPase
MRVILYTGKGGVGKTSLAAATAIASAASGKRTIVVSTDAAYSLGDSFDLGLNDEPVKIRENLWAQEISALFSAEKSWGKVQEYLSALLISQNIKDITEEELVVFPGLEELFSMLEILNHCREGKYDVLIVDCAPTGETLRLLSFPEVLKWWLEKIFPVEKLLLKIARPISKPLFGVPLPGDDTMDSIAELFQQLREMHEVLTDQEVTSVRIVVNPEKMVIREAERSFMYLNLYGFNTDAVIVNRLLPSVNLGQYFEKWGEIHHTYLRYIKDQFNPVPIFTVPLFMEEVTGFEALEIMGRECFGENPPEQFFFHGQSQKISQTVDGYVLEMALPFVEKGAISLSQKGDELTVRVGDYKRNVFLPRKLLGRDAIGAKLEDDALKIRFGGVKNDKQRL
>NC_021184.1|WP_006524042.1|553103_553334_+|hypothetical-protein
MTNRDCEACPVKELQKIHRLVEKRVLEKLPEEMREPLLEAKRQMRLALRGLIGHVFEEKKACNEKHPVESRRIDLD
>NC_021184.1|WP_006524041.1|553567_554230_+|hypothetical-protein
MKVFVSFILVAFLVHVFLYWVFRSAKISEPTETQRLNCYLSEYDFDERHNIVIQSSPEKVFEAIYNLDMSKSKVIKPLLSLRSIPYRLSPDRKPEKQEPSGLSIEQLIKNGGFFLLEEIKNQEIVIGLVGKFWHLTADMIQLSNVTNFTNFNQTGYGKVAWNFYIEQNADGTVTLSTETRILCLGEQAKSSFRLYWAVIRPYSGWIRIEMLKMIKEQVEK
>NC_021184.1|WP_052543919.1|554429_554834_+|nucleotidyltransferase-domain-containing-protein
MYRFKKIEHNVMEYIPLLIEKMRIDGDIVAIFLFGSYAEGKQTPVSDIDLAVLVDGDFPPSRYFEKELELLAIITSLLKTDEVDLVILNHAPPALSYRILSKGQYSLVNLLGNSVWRKRNYHNEKSGKGCSLLV
>NC_021184.1|WP_006524039.1|555159_555711_+|DUF4342-domain-containing-protein
MATIEQVEKLIEKANVTYDEAKTALEASGNDLLDALIYLERNGKVQPPPNGGYYNSKNQAEPEKESFGTSREKNTENGKTFTGIVNKFFKWCGYIISKGNENSFEVRRNGKYVIAVPVTILVLFLIFAFWFIVPLVVIGLFFGYRYVFKGPDLEKTDVNRVMGTAADAAENLKKEIIEGRKSQ
>NC_021184.1|WP_006524038.1|555730_556408_+|response-regulator-transcription-factor
MNEKILLIEDEEKLARFIEMELLYEGYKVEKAYDGRIGLDLALAGSFDIVILDIMLPGLNGMEVLRRIRRSSSMPVIMLTARDTTVDKVTGLDSGADDYLTKPFAIEELLARIRNALRKKVNVTMVKSLSACGLTLDIERHLAAVNNVAIELTKKEFSLLQFLLENKGIVLTRETLLEKVWGFDYTGDTNTIDVYVRYLRSKIDEPFGIKLIHTVRGVGYVIRDE
>NC_021184.1|WP_041284745.1|556400_557822_+|HAMP-domain-containing-protein
MNETKKVNSSLVFKLNTWHLSQVFLSFLWINIIMLSLFAGVLGYRAESYLANAAKTMAEQDYIIEEKPEGVKLPKILNVPFPEHMRGAIRQVITEPGTDSFGENLDGIKYRVWVALPDQGSYYAVEYNIGDYLSVFLPALFVTMIFELLFFAGSIGKGAKAMKRALQPIADLTQSAKNINTTQTAQPIAQLRDLTGTIDTINATDLDTRISISSDQNELKDLAGAINGMLDRINEAYRSQIRFVSDASHELRTPIAVIQGYANLLDRWGKNDEEALQESIEAIKSEADNMKDLVEQLLFLARGDNDSMQLSMEEINLSELVAEIMRETVMIDPNHEFKSKTDSNVYTIGDIQLIKQAIRIFIDNSVKYTPYDGAISVTTSRDGDYAKVVVQDTGIGIPPQDIPHVFDRFFRADDSRARKTGGTGLGLSIAKWIIDRHRGTVEILSRKDIGTRIIISLPVIAPPSAWSKLQTGK
>NC_021184.1|WP_006524036.1|558478_559138_+|response-regulator-transcription-factor
MALILIVEDEMPINILINRNLKLVGHECISVYDGEGVLEIIQRYTFDLILLDIMLPKMNGYEVLETVKEMDIPVIFLTSKSSLSDRVKGLTLGADDYIVKPFEMLELQARVEAVLRRTNKEQKFFVLNNVRVDLDGRQAFLNNKLVDITPQEFDLLVVLIRNRNIALSRDKLLELAWGYDFEGDTRTVDVHITKLRKKLGLGNYIKTVYKLGYRLEVLD

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Crispr_ID: NC_021184_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_5

550376-551191

Orphan

Consensus_repeat	Method
GTGGAACCAACACATTTGATGTATTGAAAT	PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	CRT

12 spacers

The CRISPR arrays of NC_021184_5

>merge|NC_021184|5|550376-551191|PILER-CR,CRISPRCasFinder,CRT
GTGGAACCAACACATTTGATGTATTGAAATATGAGTACGTGAAGGCCAATGAAATCAATAAAATAGTGGAACCAACACATTTGATGTATTGAAATATCTTACCCTTAACCCAAATTAAAGTGTTTAATTTGTGGAACCAACACATTTGATGTATTGAAATTTATTTCCTGGTTGCGTTTGATTCGGCTGGGTGTAAGGTGGAACCAACACATTTGATGTATTGAAATAGAATAGCGGGTGGAACGCCGATATATGCAAACTAGTGGAACCAACACATTTGATGTATTGAAATATTGATATGGAAACAGGAGAAAGAAAAAAGAATGAAGTGGAACCAACACATTTGATGTATTGAAATAGGAATACACCAGGCCCGGCCAAGTCTTTGGCGTGTGTGGAACCAACACATTTGATGTATTGAAATGTGAGCAGAGAAAACAAAAAGCCTCTTTCCTCTAAGTGGAACCAACACATTTGATGTATTGAAATGCAATTCCTGCGCTTTCTCTTTAGTTGGCACGATCGTGGAACCAACACATTTAATGTATTGAAATTGGTGTAATTGAAGCAGAAATAACCAAAGATGGATGTGGAACCAACACATTTGATGTATTGAAATACATACAAACCGGTTGGACTAGAAGGCGGGGGATCAGTGGAACCAACACATTTGATGTATTGAAATTTAGTTAAATCTCTCCTTTATTTAAAAGTTACTACAGTGGAACCAACACATTTGATGTATTGAAATTAATTATGAGCAACAAGGAAAGGCAAAAGCGACATGTGGAACCAACACATTTGATTTTGAGTCTC

>NC_021184|5|4|550376-551126|PILER-CR
GTGGAACCAACACATTTGATGTATTGAAAT	ATGAGTACGTGAAGGCCAATGAAATCAATAAAATA
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTACCCTTAACCCAAATTAAAGTGTTTAATTT
GTGGAACCAACACATTTGATGTATTGAAAT	TTATTTCCTGGTTGCGTTTGATTCGGCTGGGTGTAAG
GTGGAACCAACACATTTGATGTATTGAAAT	AGAATAGCGGGTGGAACGCCGATATATGCAAACTA
GTGGAACCAACACATTTGATGTATTGAAAT	ATTGATATGGAAACAGGAGAAAGAAAAAAGAATGAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGGAATACACCAGGCCCGGCCAAGTCTTTGGCGTGT
GTGGAACCAACACATTTGATGTATTGAAAT	GTGAGCAGAGAAAACAAAAAGCCTCTTTCCTCTAA
GTGGAACCAACACATTTGATGTATTGAAAT	GCAATTCCTGCGCTTTCTCTTTAGTTGGCACGATC
GTGGAACCAACACATTTAATGTATTGAAAT	TGGTGTAATTGAAGCAGAAATAACCAAAGATGGAT
GTGGAACCAACACATTTGATGTATTGAAAT	ACATACAAACCGGTTGGACTAGAAGGCGGGGGATCA
GTGGAACCAACACATTTGATGTATTGAAAT	TTAGTTAAATCTCTCCTTTATTTAAAAGTTACTACA
GTGGAACCAACACATTTGATGTATTGAAAT

>NC_021184|5|5|550376-551191|CRISPRCasFinder
GTGGAACCAACACATTTGATGTATTGAAAT	ATGAGTACGTGAAGGCCAATGAAATCAATAAAATA
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTACCCTTAACCCAAATTAAAGTGTTTAATTT
GTGGAACCAACACATTTGATGTATTGAAAT	TTATTTCCTGGTTGCGTTTGATTCGGCTGGGTGTAAG
GTGGAACCAACACATTTGATGTATTGAAAT	AGAATAGCGGGTGGAACGCCGATATATGCAAACTA
GTGGAACCAACACATTTGATGTATTGAAAT	ATTGATATGGAAACAGGAGAAAGAAAAAAGAATGAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGGAATACACCAGGCCCGGCCAAGTCTTTGGCGTGT
GTGGAACCAACACATTTGATGTATTGAAAT	GTGAGCAGAGAAAACAAAAAGCCTCTTTCCTCTAA
GTGGAACCAACACATTTGATGTATTGAAAT	GCAATTCCTGCGCTTTCTCTTTAGTTGGCACGATC
GTGGAACCAACACATTTAATGTATTGAAAT	TGGTGTAATTGAAGCAGAAATAACCAAAGATGGAT
GTGGAACCAACACATTTGATGTATTGAAAT	ACATACAAACCGGTTGGACTAGAAGGCGGGGGATCA
GTGGAACCAACACATTTGATGTATTGAAAT	TTAGTTAAATCTCTCCTTTATTTAAAAGTTACTACA
GTGGAACCAACACATTTGATGTATTGAAAT	TAATTATGAGCAACAAGGAAAGGCAAAAGCGACAT
GTGGAACCAACACATTTGATTTTGAGTCTC

>NC_021184|5|4|550376-551191|CRT
GTGGAACCAACACATTTGATGTATTGAAAT	ATGAGTACGTGAAGGCCAATGAAATCAATAAAATA
GTGGAACCAACACATTTGATGTATTGAAAT	ATCTTACCCTTAACCCAAATTAAAGTGTTTAATTT
GTGGAACCAACACATTTGATGTATTGAAAT	TTATTTCCTGGTTGCGTTTGATTCGGCTGGGTGTAAG
GTGGAACCAACACATTTGATGTATTGAAAT	AGAATAGCGGGTGGAACGCCGATATATGCAAACTA
GTGGAACCAACACATTTGATGTATTGAAAT	ATTGATATGGAAACAGGAGAAAGAAAAAAGAATGAA
GTGGAACCAACACATTTGATGTATTGAAAT	AGGAATACACCAGGCCCGGCCAAGTCTTTGGCGTGT
GTGGAACCAACACATTTGATGTATTGAAAT	GTGAGCAGAGAAAACAAAAAGCCTCTTTCCTCTAA
GTGGAACCAACACATTTGATGTATTGAAAT	GCAATTCCTGCGCTTTCTCTTTAGTTGGCACGATC
GTGGAACCAACACATTTAATGTATTGAAAT	TGGTGTAATTGAAGCAGAAATAACCAAAGATGGAT
GTGGAACCAACACATTTGATGTATTGAAAT	ACATACAAACCGGTTGGACTAGAAGGCGGGGGATCA
GTGGAACCAACACATTTGATGTATTGAAAT	TTAGTTAAATCTCTCCTTTATTTAAAAGTTACTACA
GTGGAACCAACACATTTGATGTATTGAAAT	TAATTATGAGCAACAAGGAAAGGCAAAAGCGACAT
GTGGAACCAACACATTTGATTTTGAGTCTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_052543919.1\|554429_554834_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|376187
NC_021184.1\|WP_083940007.1\|545826_546984_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271188
NC_021184.1\|WP_157872710.1\|549080_550248_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_021184.1\|WP_006524054.1\|538827_538998_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_041284745.1\|556400_557822_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_021184.1\|WP_006524039.1\|555159_555711_+\|DUF4342-domain-containing-protein	unknown	unknown	gnl\|CDD\|270543
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_021184.1\|WP_006524035.1\|559134_560529_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_021184.1\|WP_006524044.1\|551338_551818_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_021184.1\|WP_006524049.1\|544859_545834_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271178
NC_021184.1\|WP_006524043.1\|551935_553123_+\|ArsA-family-ATPase	unknown	unknown	gnl\|CDD\|349755
NC_021184.1\|WP_006524041.1\|553567_554230_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006524038.1\|555730_556408_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271183
NC_021184.1\|WP_006524036.1\|558478_559138_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	unknown	unknown	gnl\|CDD\|379963
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271193
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	unknown	unknown	gnl\|CDD\|377437
NC_021184.1\|WP_006524042.1\|553103_553334_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_052543919.1\|554429_554834_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	8.96192e-22
NC_021184.1\|WP_083940007.1\|545826_546984_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271188	cd01188, INT_RitA_C_like, C-terminal catalytic domain of recombinase RitA, a component of the recombinase trio. Recombinases RitA (also known as pAE1), RitB, and RitC are encoded by three adjacent and overlapping genes. Collectively they are known as the Recombinase in Trio (RIT). This RitA family includes various bacterial integrases and integrases from the deletion-prone region of plasmid pAE1 of Alcaligenes eutrophus H1. All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.07673e-73
NC_021184.1\|WP_157872710.1\|549080_550248_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	6.05763e-37
NC_021184.1\|WP_041284745.1\|556400_557822_+\|HAMP-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	3.49204e-59
NC_021184.1\|WP_006521022.1\|542552_543770_-\|IS256-like-element-ISDgi1-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	6.30561e-118
NC_021184.1\|WP_006524039.1\|555159_555711_+\|DUF4342-domain-containing-protein	gnl\|CDD\|270543	cd14360, UBA_NAC_like_bac, UBA-like domain found in uncharacterized bacteria proteins similar to eukaryotic nascent polypeptide-associated complex proteins (NAC). This subfamily contains a group of uncharacterized proteins found in bacteria. They all contain an N-terminal ubiquitin-associated (UBA) that shows high sequence similarity with that of eukaryotic nascent polypeptide-associated complex proteins (NAC) which is one of the cytosolic chaperones that contact the nascent polypeptide chains as they emerge from the ribosome and assist in post-translational processes.	7.58082e-13
NC_021184.1\|WP_006524053.1\|539074_539830_+\|RNA-directed-DNA-polymerase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	7.69041e-102
NC_021184.1\|WP_006524035.1\|559134_560529_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.70806e-46
NC_021184.1\|WP_006524044.1\|551338_551818_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.42971e-16
NC_021184.1\|WP_006524049.1\|544859_545834_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271178	cd00797, INT_RitB_C_like, C-terminal catalytic domain of recombinase RitB, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	5.58573e-67
NC_021184.1\|WP_006524043.1\|551935_553123_+\|ArsA-family-ATPase	gnl\|CDD\|349755	cd02035, ArsA, Arsenical pump-driving ATPase ArsA. ArsA ATPase functions as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents. The pump is composed of two subunits, the catalytic ArsA subunit and the membrane subunit ArsB, which are encoded by arsA and arsB genes, respectively. Arsenic efflux in bacteria is catalyzed by either ArsB alone or by ArsAB complex. The ATP-coupled pump, however, is more efficient. ArsA is composed of two homologous halves, A1 and A2, connected by a short linker sequence.	1.39851e-103
NC_021184.1\|WP_006524038.1\|555730_556408_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.41871e-84
NC_021184.1\|WP_006524050.1\|543859_544873_-\|site-specific-integrase	gnl\|CDD\|271183	cd01182, INT_RitC_C_like, C-terminal catalytic domain of recombinase RitC, a component of the recombinase trio. Recombinases belonging to the RitA (also known as pAE1 due to its presence in the deletion prone region of plasmid pAE1 of Alcaligenes eutrophus H1), RitB, and RitC families are associated in a complex referred to as a Recombinase in Trio (RIT) element. These RIT elements consist of three adjacent and unidirectional overlapping genes, one from each family (ritABC in order of transcription). All three integrases contain a catalytic motif, suggesting that they are all active enzymes. However, their specific roles are not yet fully understood. All three families belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism.	7.52778e-85
NC_021184.1\|WP_006524036.1\|558478_559138_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	8.74076e-72
NC_021184.1\|WP_083939749.1\|537447_537684_+\|DUF5348-domain-containing-protein	gnl\|CDD\|379963	pfam17295, DUF5348, Domain of unknown function (DUF5348).	7.17066e-15
NC_021184.1\|WP_006524052.1\|540009_540891_+\|site-specific-integrase	gnl\|CDD\|271193	cd01193, INT_IntI_C, Integron integrase and similar protiens, C-terminal catalytic domain. Integron integrases mediate site-specific DNA recombination between a proximal primary site (attI) and a secondary target site (attC) found within mobile gene cassettes encoding resistance or virulence factors. Unlike other site specific recombinases, the attC sites lack sequence conservation. Integron integrase exhibits broader DNA specificity by recognizing the non-conserved attC sites. The structure shows that DNA target site recognition are not dependent on canonical DNA but on the position of two flipped-out bases that interact in cis and in trans with the integrase. Integron-integrases are present in many natural occurring mobile elements, including transposons and conjugative plasmids. Vibrio, Shewanella, Xanthomonas, and Pseudomonas species harbor chromosomal super-integrons. All integron-integrases carry large inserts unlike the TnpF ermF-like proteins also seen in this group.	1.48872e-62
NC_021184.1\|WP_006524051.1\|540883_542011_+\|IS91-family-transposase	gnl\|CDD\|377437	pfam04986, Y2_Tnp, Putative transposase. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.	2.79612e-81

>NC_021184.1|WP_157872710.1|549080_550248_-|IS3-family-transposase
MQKKQWSPEQKLQIVLEALKEERHIGEIASEYGVHVSVIHRWKKELLEGADKVFATSKSAKAAAQEKRKQEETIENLYAQVGRLTTQLDWLKKNLAVSYPVNERKAMVDWDISNSHLTIKAQAGLLSLNRTGLYWTAKKVSKHEVEIKHLIDKIHTQHPFKGSRRIVDDINNMDGVDYKVNRKRIQRYMREMGIRVIYPGPNLSKRNRAQYVYPYLLRNVKPAHPNHVWGIDITYCAMQGRWMYLVAIIDWYSRMIVGYELSDTMNKEFVIKAVKKAIETHGAPIILNSDQGSQFTSPVYINTLKEHGIKISMDGKGRALDNAIAERFWRTIKWEDIYLKNYETPRALRQGITAFMRYYNFERPHTSIGKKTPADVYYATTNLPQQSA
>NC_021184.1|WP_083940007.1|545826_546984_-|tyrosine-type-recombinase/integrase
MSFYRRRWLKLLKFAEERGATYFSEQLGLDFLETQFHILRKDLDNTLSQRDVQDIRVVRMIGDFQLHHVVLRRYYKHHELLTDPYYVDISTDFRYHCERKEYSSVTIDHYVKQSARFMDYLLAQGIYNCSKITLPLVNGYIRTLVGYTYKTVEQNICSIRAFLRYLNDKGILNEDLASKTPMVQARKQTRIPSVWTKEELKALIGAIDRGSPKGKRDYAIILLACILGLRVTDIKQLTFSNFNWEEKKLTFTQSKTHETVTLPIPKEVGWAVIDYLQYGRPKVDSPVIFVRHMAPFLPFSEGDHLSQLIKSYMQIAHLPTLKKRRGMHSLRHTAASRMLEHDTPLEVISDILGHSNTDSTAVYLKVDISKLRECALDMPEVTPHA
>NC_021184.1|WP_006524049.1|544859_545834_-|tyrosine-type-recombinase/integrase
MHDLSFKGPFAEYITDHISLKRAIGYKFEADAKNLMRFSIFTAEKYPDATALTREIVLDWCTKKLYEAQATQCARASTLRQLAIYMDNIGINAYILPKGYYPAEEKYIPYIFTENELLRFFSATDQCHYVSECPYRHLVMPVFFRMIYSCGLRPQEARLLKTEDVNLNDGILSIQHSKKDNSRLVPMSAALTARCRDYAIGIGDSKWFFPGLNGKPMTAGNAYHNFRRFLWKAGISHGGRGKGPRIYDFRHVYACHCLKKWVADGKDLSVYLPILKTYMGHDSFKDTAYYLRLTADVFPDITIKLEGYYPDIIPSLGGAVDAIH
>NC_021184.1|WP_006524050.1|543859_544873_-|site-specific-integrase
MQSTDFAEHLTQFLTVYLPAQKNASKNTIASYRDTFKLLLQYCQEQQDIPAEKLTMRMLTHDLVADFLGWLETNRNCSISTRNQRLTAIHSFFRYAQYEEPMGLANFQKVLSIPVKKAPKSDVPHLNTDAMQLLLSQPDKSTPKGRRDLTLLSVLYDSGCRVQELVDLKVRDVILTDPSVLVLTGKGNKTRRVPLMKNTATLLDSYIHENKLEKPWKSDYLLFTNKQHNKLTKEGVSYIISKYVTSARQVSSIVPERVTPHMFRHSKSVHLLQAGVNLIYIRDFLGHVDIKTTEVYAKCDTELKRRAIENAYPELVDSDLPDWSQNTSLLNWLSSLK
>NC_021184.1|WP_006521022.1|542552_543770_-|IS256-like-element-ISDgi1-family-transposase
MQAMQDKTIKELAKDCRTVEDVHEMLKNLFKDTLQQIFEAEIEEHLGYKKHSIEGNNTGNSRNGYNKKTIQTKFGKTEVEIPRDRNGEFEPRIIGKYEKTSNQLEDQIIAMYAKGMSTRDIEDHMRDIYGIDVSPTMVSKITDKILPMIAEWQSRTLDRIYPIVFLDAIHFKVRKDNRIINKAAYSVLALNMAGQKEILGIWIGENESASFWLGVCNDLKSRGVQDILIACKDGLSGFSEAINTVFPKTEIQLCIIHQIRNSLKYVPYKEQKELMADLKQVYQALTLEEAELAFEIFKENWGKRHPIIIRSWEKNWLELTAYFKYPYEIRKMIYTTNIIEGYHRQLRKVTKTKTAYPTDDALKKIIYLATVEAAKKWTMPVKDWKNCISQFAIYFGDRIESEMAI
>NC_021184.1|WP_006524051.1|540883_542011_+|IS91-family-transposase
MLELQDIFAQHGKTYRLNHSLLLNQVKVMRAIENCRTSALGGHTDECDECGFIRISYNSCRNRHCPKCQTLNKERWIEARKDDLLNVGYFHVVFTVPDTLNPVAYQNQTVVYNILFKAAAETLSELAADKKYLGAQIGFTEILHTWGQNLMYHPHIHCIVPGGGLNSCGKWVNSRKKFFIPVKVLSRKFRGKFLYYLKQAKLEFYSLISYLQDDGMFNNFISSLYQKEWIVYCKPPFKNAGCVVEYLGRYTHRVAISNSRILKLEDGVVTFKWRDYKDNNKQKNMNLTADEFIRRFLIHVLPNGFTKIRHYGLLSPRNKATKLKLCKKLTNTSINDKPKVKLSTLDFLKKLTGRDFSICPCCGIGHLSRASPGKM
>NC_021184.1|WP_006524052.1|540009_540891_+|site-specific-integrase
MENKEQVLLRMKKDILLRGLSKNTLESYTLNARIFLEYCNRPVEQLNEYDIRNFLWYLINEKKASPGTVNTYSAAIRFLFAVTLNRTLNYLQIPRQKKRKTFPEVLTREEVFSIIESCKNIKHKAMLMVVYSSGLRVSEAAALKIQHIDSKNMRIFVEDGKGGKDRYTVLSATCLSVLREYWKRYRPKNPEGWLFLGTYNVSHITTRGIAFAFNEAVKRANITKNVSIHSLRHSFATHLLEDGATLLQIKELLGHTSIKSTTIYVHLANVTSDIKSPLDNSPAYRSLEVPSNA
>NC_021184.1|WP_006524053.1|539074_539830_+|RNA-directed-DNA-polymerase
MNVTKKGAKCSQLPTGGSRMEGSPQKNSAEHKGYAGAHNPLRITENNITNADMSKERLLEEIVDRSNMNKAYKRVKSNKGAHGIDGMGVDKLLQYLKENGGQLRQSILDGKYCPNPVRRVEIPKEDGKKKRKLGIPTVVDRVVQQAIAQVLTPICEKQFSDNSYGFRPGRSAHDAIRKCRDNISEGYNYVVDMDLEKYFDTVNQSKLVEVLSRTIKDGRVISLIHKYLRAGVIIKHKFEETKVGVPQGGLC
>NC_021184.1|WP_006524054.1|538827_538998_+|hypothetical-protein
MCRLGKVAIQTEAQNYPEAYGVDVADRWKERLRSYPGRSHGREEMNFKSRLKQDLS
>NC_021184.1|WP_083939749.1|537447_537684_+|DUF5348-domain-containing-protein
MIPRKRDGRILYNVKTDRWDVWDVYSKPVALHCGECFEIKLGDHFLSCRIEMDSEWVIYLSNTRFHLHPKVSYWIRVE
>NC_021184.1|WP_006524044.1|551338_551818_+|MarR-family-transcriptional-regulator
MSSNIDIYEFILDNIRKIVVPEELITLELSISRFELLALMLSEKHQTVTMSNLAQGMSVPMSTATGIVDRLVKKGLLKRGRSEEDRRVVTVSLTDNGKTLVEDLKKHFHDFLNRIRSLITKEEFDMAVQLIRKVVLGFQKSETNSDKKPGQYRRNIEIE
>NC_021184.1|WP_006524043.1|551935_553123_+|ArsA-family-ATPase
MRVILYTGKGGVGKTSLAAATAIASAASGKRTIVVSTDAAYSLGDSFDLGLNDEPVKIRENLWAQEISALFSAEKSWGKVQEYLSALLISQNIKDITEEELVVFPGLEELFSMLEILNHCREGKYDVLIVDCAPTGETLRLLSFPEVLKWWLEKIFPVEKLLLKIARPISKPLFGVPLPGDDTMDSIAELFQQLREMHEVLTDQEVTSVRIVVNPEKMVIREAERSFMYLNLYGFNTDAVIVNRLLPSVNLGQYFEKWGEIHHTYLRYIKDQFNPVPIFTVPLFMEEVTGFEALEIMGRECFGENPPEQFFFHGQSQKISQTVDGYVLEMALPFVEKGAISLSQKGDELTVRVGDYKRNVFLPRKLLGRDAIGAKLEDDALKIRFGGVKNDKQRL
>NC_021184.1|WP_006524042.1|553103_553334_+|hypothetical-protein
MTNRDCEACPVKELQKIHRLVEKRVLEKLPEEMREPLLEAKRQMRLALRGLIGHVFEEKKACNEKHPVESRRIDLD
>NC_021184.1|WP_006524041.1|553567_554230_+|hypothetical-protein
MKVFVSFILVAFLVHVFLYWVFRSAKISEPTETQRLNCYLSEYDFDERHNIVIQSSPEKVFEAIYNLDMSKSKVIKPLLSLRSIPYRLSPDRKPEKQEPSGLSIEQLIKNGGFFLLEEIKNQEIVIGLVGKFWHLTADMIQLSNVTNFTNFNQTGYGKVAWNFYIEQNADGTVTLSTETRILCLGEQAKSSFRLYWAVIRPYSGWIRIEMLKMIKEQVEK
>NC_021184.1|WP_052543919.1|554429_554834_+|nucleotidyltransferase-domain-containing-protein
MYRFKKIEHNVMEYIPLLIEKMRIDGDIVAIFLFGSYAEGKQTPVSDIDLAVLVDGDFPPSRYFEKELELLAIITSLLKTDEVDLVILNHAPPALSYRILSKGQYSLVNLLGNSVWRKRNYHNEKSGKGCSLLV
>NC_021184.1|WP_006524039.1|555159_555711_+|DUF4342-domain-containing-protein
MATIEQVEKLIEKANVTYDEAKTALEASGNDLLDALIYLERNGKVQPPPNGGYYNSKNQAEPEKESFGTSREKNTENGKTFTGIVNKFFKWCGYIISKGNENSFEVRRNGKYVIAVPVTILVLFLIFAFWFIVPLVVIGLFFGYRYVFKGPDLEKTDVNRVMGTAADAAENLKKEIIEGRKSQ
>NC_021184.1|WP_006524038.1|555730_556408_+|response-regulator-transcription-factor
MNEKILLIEDEEKLARFIEMELLYEGYKVEKAYDGRIGLDLALAGSFDIVILDIMLPGLNGMEVLRRIRRSSSMPVIMLTARDTTVDKVTGLDSGADDYLTKPFAIEELLARIRNALRKKVNVTMVKSLSACGLTLDIERHLAAVNNVAIELTKKEFSLLQFLLENKGIVLTRETLLEKVWGFDYTGDTNTIDVYVRYLRSKIDEPFGIKLIHTVRGVGYVIRDE
>NC_021184.1|WP_041284745.1|556400_557822_+|HAMP-domain-containing-protein
MNETKKVNSSLVFKLNTWHLSQVFLSFLWINIIMLSLFAGVLGYRAESYLANAAKTMAEQDYIIEEKPEGVKLPKILNVPFPEHMRGAIRQVITEPGTDSFGENLDGIKYRVWVALPDQGSYYAVEYNIGDYLSVFLPALFVTMIFELLFFAGSIGKGAKAMKRALQPIADLTQSAKNINTTQTAQPIAQLRDLTGTIDTINATDLDTRISISSDQNELKDLAGAINGMLDRINEAYRSQIRFVSDASHELRTPIAVIQGYANLLDRWGKNDEEALQESIEAIKSEADNMKDLVEQLLFLARGDNDSMQLSMEEINLSELVAEIMRETVMIDPNHEFKSKTDSNVYTIGDIQLIKQAIRIFIDNSVKYTPYDGAISVTTSRDGDYAKVVVQDTGIGIPPQDIPHVFDRFFRADDSRARKTGGTGLGLSIAKWIIDRHRGTVEILSRKDIGTRIIISLPVIAPPSAWSKLQTGK
>NC_021184.1|WP_006524036.1|558478_559138_+|response-regulator-transcription-factor
MALILIVEDEMPINILINRNLKLVGHECISVYDGEGVLEIIQRYTFDLILLDIMLPKMNGYEVLETVKEMDIPVIFLTSKSSLSDRVKGLTLGADDYIVKPFEMLELQARVEAVLRRTNKEQKFFVLNNVRVDLDGRQAFLNNKLVDITPQEFDLLVVLIRNRNIALSRDKLLELAWGYDFEGDTRTVDVHITKLRKKLGLGNYIKTVYKLGYRLEVLD
>NC_021184.1|WP_006524035.1|559134_560529_+|HAMP-domain-containing-histidine-kinase
MKFRTFIATFALFLIVFFSSLLFISVFIINNQMDIIKERGINEHYFISSSFGKDLMAIVDRGGNLGDAIEQLFNFYAEYYQKQGVYLELLSQGKIIYSNLPERSNKLTSYAIEPGIRKATFQNIGDSVYFKVVGELPGTDNRFSIQYLHDISGNLKAWQTTQRILLLVGIIFTIILAVSLQLILNRVFEPLDMVSMASRKIANGQYDNRIIVSGRHELAEMAESFNNMAEEIQRRITQLAEAFEQKQQFVDNLAHEIRTPLTSVYGFAEYIQKTTISDEEKMFAASYIMSESQYMLNISNRLLELATLRNQVIKMKVVDVNSLFEHSQKSLAAKLAENQISLKWKIDIDSTYGDKDLLQSLLVNFTDNAIKACNPGGIIVWNAYIENGCRVLSVQDNGWGIPQNEINKVTDPFYRVDKSRNRAKGGVGLGLSICEQIANCHNAVLSIESLPNVGTIVKLTFTSL

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Crispr_ID: NC_021184_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_6

832966-834392

TypeI-B

Consensus_repeat	Method
GTTTTTAGACTACCTATGAGGAATTGAAAC	PILER-CR
GTTTTTAGACTACCTATGAGGAATTGAAAC	CRISPRCasFinder
GTTTTTAGACTACCTATGAGGAATTGAAAC	CRT

21 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b1,cas6

The CRISPR arrays of NC_021184_6

>merge|NC_021184|6|832966-834392|PILER-CR,CRISPRCasFinder,CRT
GTTTTTAGACTACCTATGAGGAATTGAAACTGTTGTTGGGCGCGGGATTCCATTTGCCCGAAATATCGTTTTTAGACTACCTATGAGGAATTGAAACCCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGAGTTTTTAGACTACCTATGAGGAATTGAAACACACATCTGGCAAGGACACAGATTCTGGCTTTAGCAGTTTTTAGACTACCTATGAGGAATTGAAACCCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGAGTTTTTAGACTACCTATGAGGAATTGAAACACACATCTGGCAAGGACACAGATTCTGGCTTCAGCAGTTTTTAGACTACCTATGAGGAATTGAAACCAAGCAACAATCGTCCAGAGAAACCACACTACTGAAAGTTTTTAGACTACCTATGAGGAATTGAAACTCTAATATTCTATTCAGCACTGTGGCAAGCTCCCCCGTTTTTAGACTACCTATGAGGAATTGAAACTAGGTCCGGTATACCTTATCAGGCACAACTTCCCGCCGTTTTTAGACTACCTATGAGGAATTGAAACCTGGACAATCGTCACGCGCCTTGCGTTGACCTTTTCTGTTTTTAGACTACCTATGAGGAATTGAAACTGCGCTATGACGGTCTCACTGCAACAGCAGACCACCTCGGTTTTTAGACTACCTATGAGGAATTGAAACTTTTTAATTCTATCTCTATCTTGAATTAAGCGTAGTTGTTTTTAGACTACCTATGAGGAATTGAAACTTTTTGGAGATGGAAACAGGCGTAATTTTGATCCGGGTTTTTAGACTACCTATGAGGAATTGAAACCTGTCCTATATGTGGAATTAGATTCACAGGGATCAACGTTTTTAGACTACCTATGAGGAATTGAAACTATCTCGCACCCGGGGCAATGTTTTAGCCAGCGGGGTTTTTAGACTACCTATGAGGAATTGAAACTTGCGCAGAAGTCGTATACCTCCTCTGTCCTAGCGCCAGTTTTTAGACTACCTATGAGGAATTGAAACTTAATTCTTCTGCAATCATCAAATTTTACTTCTCGCGTTTTTAGACTACCTATGAGGAATTGAAACTCATTGTGCGGGTCATTTCCAAACCCCATTCCACGTGTTTTTAGACTACCTATGAGGAATTGAAACGCGTATCACCCACTAGGTGCTCACCTCTTTGTGTTCTGTTTTTAGACTACCTATGAGGAATTGAAACATGCCCTGTGCAAACATACTTACAAAGTTTGGACCCGTTTTTAGACTACCTATGAGGAATTGAAACCGCTCTCGGTTGATAACCTGTACCGCAAGTGGAAGGCGTTTTTAGACTACCTATGAGGAATTGAAACAGCTCCTTCATAACTCCGATTGTTGCCCCGGCCAGGTTTTTAGACTACCTATGAGGAATTGAAAC

>NC_021184|6|5|832966-834392|PILER-CR
GTTTTTAGACTACCTATGAGGAATTGAAAC	TGTTGTTGGGCGCGGGATTCCATTTGCCCGAAATATC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGA
GTTTTTAGACTACCTATGAGGAATTGAAAC	ACACATCTGGCAAGGACACAGATTCTGGCTTTAGCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	CCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGA
GTTTTTAGACTACCTATGAGGAATTGAAAC	ACACATCTGGCAAGGACACAGATTCTGGCTTCAGCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	CAAGCAACAATCGTCCAGAGAAACCACACTACTGAAA
GTTTTTAGACTACCTATGAGGAATTGAAAC	TCTAATATTCTATTCAGCACTGTGGCAAGCTCCCCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TAGGTCCGGTATACCTTATCAGGCACAACTTCCCGCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CTGGACAATCGTCACGCGCCTTGCGTTGACCTTTTCT
GTTTTTAGACTACCTATGAGGAATTGAAAC	TGCGCTATGACGGTCTCACTGCAACAGCAGACCACCTCG
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTTTTAATTCTATCTCTATCTTGAATTAAGCGTAGTT
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTTTTGGAGATGGAAACAGGCGTAATTTTGATCCGG
GTTTTTAGACTACCTATGAGGAATTGAAAC	CTGTCCTATATGTGGAATTAGATTCACAGGGATCAAC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TATCTCGCACCCGGGGCAATGTTTTAGCCAGCGGG
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTGCGCAGAAGTCGTATACCTCCTCTGTCCTAGCGCCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTAATTCTTCTGCAATCATCAAATTTTACTTCTCGC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TCATTGTGCGGGTCATTTCCAAACCCCATTCCACGT
GTTTTTAGACTACCTATGAGGAATTGAAAC	GCGTATCACCCACTAGGTGCTCACCTCTTTGTGTTCT
GTTTTTAGACTACCTATGAGGAATTGAAAC	ATGCCCTGTGCAAACATACTTACAAAGTTTGGACCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CGCTCTCGGTTGATAACCTGTACCGCAAGTGGAAGGC
GTTTTTAGACTACCTATGAGGAATTGAAAC	AGCTCCTTCATAACTCCGATTGTTGCCCCGGCCAG
GTTTTTAGACTACCTATGAGGAATTGAAAC

>NC_021184|6|6|832966-834392|CRISPRCasFinder
GTTTTTAGACTACCTATGAGGAATTGAAAC	TGTTGTTGGGCGCGGGATTCCATTTGCCCGAAATATC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGA
GTTTTTAGACTACCTATGAGGAATTGAAAC	ACACATCTGGCAAGGACACAGATTCTGGCTTTAGCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	CCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGA
GTTTTTAGACTACCTATGAGGAATTGAAAC	ACACATCTGGCAAGGACACAGATTCTGGCTTCAGCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	CAAGCAACAATCGTCCAGAGAAACCACACTACTGAAA
GTTTTTAGACTACCTATGAGGAATTGAAAC	TCTAATATTCTATTCAGCACTGTGGCAAGCTCCCCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TAGGTCCGGTATACCTTATCAGGCACAACTTCCCGCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CTGGACAATCGTCACGCGCCTTGCGTTGACCTTTTCT
GTTTTTAGACTACCTATGAGGAATTGAAAC	TGCGCTATGACGGTCTCACTGCAACAGCAGACCACCTCG
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTTTTAATTCTATCTCTATCTTGAATTAAGCGTAGTT
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTTTTGGAGATGGAAACAGGCGTAATTTTGATCCGG
GTTTTTAGACTACCTATGAGGAATTGAAAC	CTGTCCTATATGTGGAATTAGATTCACAGGGATCAAC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TATCTCGCACCCGGGGCAATGTTTTAGCCAGCGGG
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTGCGCAGAAGTCGTATACCTCCTCTGTCCTAGCGCCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTAATTCTTCTGCAATCATCAAATTTTACTTCTCGC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TCATTGTGCGGGTCATTTCCAAACCCCATTCCACGT
GTTTTTAGACTACCTATGAGGAATTGAAAC	GCGTATCACCCACTAGGTGCTCACCTCTTTGTGTTCT
GTTTTTAGACTACCTATGAGGAATTGAAAC	ATGCCCTGTGCAAACATACTTACAAAGTTTGGACCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CGCTCTCGGTTGATAACCTGTACCGCAAGTGGAAGGC
GTTTTTAGACTACCTATGAGGAATTGAAAC	AGCTCCTTCATAACTCCGATTGTTGCCCCGGCCAG
GTTTTTAGACTACCTATGAGGAATTGAAAC

>NC_021184|6|5|832966-834392|CRT
GTTTTTAGACTACCTATGAGGAATTGAAAC	TGTTGTTGGGCGCGGGATTCCATTTGCCCGAAATATC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGA
GTTTTTAGACTACCTATGAGGAATTGAAAC	ACACATCTGGCAAGGACACAGATTCTGGCTTTAGCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	CCGCCGAGGCCAATTCATCTAAACCGGTCCCGCCGA
GTTTTTAGACTACCTATGAGGAATTGAAAC	ACACATCTGGCAAGGACACAGATTCTGGCTTCAGCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	CAAGCAACAATCGTCCAGAGAAACCACACTACTGAAA
GTTTTTAGACTACCTATGAGGAATTGAAAC	TCTAATATTCTATTCAGCACTGTGGCAAGCTCCCCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TAGGTCCGGTATACCTTATCAGGCACAACTTCCCGCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CTGGACAATCGTCACGCGCCTTGCGTTGACCTTTTCT
GTTTTTAGACTACCTATGAGGAATTGAAAC	TGCGCTATGACGGTCTCACTGCAACAGCAGACCACCTCG
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTTTTAATTCTATCTCTATCTTGAATTAAGCGTAGTT
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTTTTGGAGATGGAAACAGGCGTAATTTTGATCCGG
GTTTTTAGACTACCTATGAGGAATTGAAAC	CTGTCCTATATGTGGAATTAGATTCACAGGGATCAAC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TATCTCGCACCCGGGGCAATGTTTTAGCCAGCGGG
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTGCGCAGAAGTCGTATACCTCCTCTGTCCTAGCGCCA
GTTTTTAGACTACCTATGAGGAATTGAAAC	TTAATTCTTCTGCAATCATCAAATTTTACTTCTCGC
GTTTTTAGACTACCTATGAGGAATTGAAAC	TCATTGTGCGGGTCATTTCCAAACCCCATTCCACGT
GTTTTTAGACTACCTATGAGGAATTGAAAC	GCGTATCACCCACTAGGTGCTCACCTCTTTGTGTTCT
GTTTTTAGACTACCTATGAGGAATTGAAAC	ATGCCCTGTGCAAACATACTTACAAAGTTTGGACCC
GTTTTTAGACTACCTATGAGGAATTGAAAC	CGCTCTCGGTTGATAACCTGTACCGCAAGTGGAAGGC
GTTTTTAGACTACCTATGAGGAATTGAAAC	AGCTCCTTCATAACTCCGATTGTTGCCCCGGCCAG
GTTTTTAGACTACCTATGAGGAATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_006521010.1\|824742_826512_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_021184.1\|WP_006521026.1\|848724_849327_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225136
NC_021184.1\|WP_015617913.1\|844367_846104_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_021184.1\|WP_015617912.1\|832522_832786_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_021184.1\|WP_006521014.1\|830923_831430_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_021184.1\|WP_157872714.1\|826495_827458_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_021184.1\|WP_006521019.1\|836946_837636_+\|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl\|CDD\|223881
NC_021184.1\|WP_041285180.1\|834508_835051_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006521015.1\|831501_832494_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_021184.1\|WP_006521022.1\|843057_844275_-\|IS256-like-element-ISDgi1-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_021184.1\|WP_006521018.1\|836206_836950_+\|DUF2162-domain-containing-protein	unknown	unknown	gnl\|CDD\|370753
NC_021184.1\|WP_006521009.1\|824293_824548_-\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006521013.1\|828349_830698_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_021184.1\|WP_006521025.1\|847143_848706_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173855
NC_021184.1\|WP_006521024.1\|846745_847078_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_157872871.1\|822687_822957_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NC_021184.1\|WP_006521012.1\|827468_828197_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_021184.1\|WP_006521021.1\|837953_842693_+\|cobaltochelatase-subunit-CobN	unknown	unknown	gnl\|CDD\|376805
NC_021184.1\|WP_052543922.1\|837601_837934_+\|DUF2149-domain-containing-protein	unknown	unknown	gnl\|CDD\|227087
NC_021184.1\|WP_006521007.1\|823371_824136_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_006521010.1\|824742_826512_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.50354e-167
NC_021184.1\|WP_006521026.1\|848724_849327_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	4.27535e-33
NC_021184.1\|WP_015617913.1\|844367_846104_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	5.93556e-19
NC_021184.1\|WP_006521018.1\|836206_836950_+\|DUF2162-domain-containing-protein	gnl\|CDD\|370753	pfam09930, DUF2162, Predicted transporter (DUF2162). Members of this family of bacterial proteins are thought to be membrane transporters, but their exact function has not, as yet, been elucidated.	1.53128e-47
NC_021184.1\|WP_006521014.1\|830923_831430_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.33768e-71
NC_021184.1\|WP_157872714.1\|826495_827458_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	2.22444e-94
NC_021184.1\|WP_006521019.1\|836946_837636_+\|MotA/TolQ/ExbB-proton-channel-family-protein	gnl\|CDD\|223881	COG0811, TolQ, Biopolymer transport proteins [Intracellular trafficking and secretion].	4.11613e-12
NC_021184.1\|WP_006521015.1\|831501_832494_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.01539e-171
NC_021184.1\|WP_006521022.1\|843057_844275_-\|IS256-like-element-ISDgi1-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	6.30561e-118
NC_021184.1\|WP_006521025.1\|847143_848706_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173855	cd08490, PBP2_NikA_DppA_OppA_like_3, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.86423e-141
NC_021184.1\|WP_006521013.1\|828349_830698_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	5.90045e-48
NC_021184.1\|WP_052543922.1\|837601_837934_+\|DUF2149-domain-containing-protein	gnl\|CDD\|227087	COG4744, COG4744, Uncharacterized conserved protein [Function unknown].	9.17542e-27
NC_021184.1\|WP_157872871.1\|822687_822957_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	3.29647e-05
NC_021184.1\|WP_006521012.1\|827468_828197_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	7.29546e-36
NC_021184.1\|WP_006521021.1\|837953_842693_+\|cobaltochelatase-subunit-CobN	gnl\|CDD\|376805	pfam02514, CobN-Mg_chel, CobN/Magnesium Chelatase. This family contains a domain common to the cobN protein and to magnesium protoporphyrin chelatase. CobN is implicated in the conversion of hydrogenobyrinic acid a,c-diamide to cobyrinic acid. Magnesium protoporphyrin chelatase is involved in chlorophyll biosynthesis.	0
NC_021184.1\|WP_006521007.1\|823371_824136_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	5.47924e-32
NC_021184.1\|WP_015617912.1\|832522_832786_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.22318e-31

>NC_021184.1|WP_015617912.1|832522_832786_+|CRISPR-associated-endonuclease-Cas2
MFVILVYDVGQKRVAKVLKKCRQYLNWVQNAVLEGEVSDANLKKLKMELERIIHKDEDSVIFYSLRTTKYSSREIMGLKKGGDENII
>NC_021184.1|WP_006521015.1|831501_832494_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTLYVFSSGELSRKDNTLFFETEEGRRFIPVEDTGEIMIFGELTVNKKLLEFLSIKEIVLHFFNYHGYYMGSFYPREHLNSGFMTLRQAEHYLDEERRLIIAKEFVRGAARNIRQVLKYYHGREKDVARQLNAIENLIAPIDECKDISTLMALEGNIRDHYYHAFDEIVGNPDFIFQERTRRPPKNYLNTLISFGNSLMYTICLSEIYKTHLDPRIGYLHSTNFRRFTLNLDLAEIFKPIIVDRLIFSLLGKKMITKESFDRVTEGIMMKEKARKCFVENLDEKLKTTIKHRDIGRPVSYRRLIRLELYKMEKHLMGEKEYQAFVARW
>NC_021184.1|WP_006521014.1|830923_831430_+|CRISPR-associated-protein-Cas4
MNAREINVSGTLVWYYYICPREVWLIGHQITADQDDANVSLGRFIQDYTYPRERKELAVGQSKMDVFRVTDEGLVIGEVKKSSKFKSSARMQLAFYLSELKQRGIEARGELRFPKEKRKEEVMLNEQTERELDKVCREILRILYLPAPPEPKKISFCRKCAYAEFCWS
>NC_021184.1|WP_006521013.1|828349_830698_+|CRISPR-associated-helicase/endonuclease-Cas3
MLSAGREVKFWDAGVLNDILKILSFAHDFGKATPYFQKYIENPYKQKSGPLARHSLLSAVVGYRLAKYYFEGYRDAQKLSLFVYVAIKRHHGNLHSIEDEFLTFSDQDQDLLLKQVRSIDFSMLEETWKPLVIQLPPGLSKILPFTCEKLEIWIKDMQEELNQISLWWLLNEDKNQSFLGDKNEPQAEYSLDNYFKFLYIYSLLLDADKSQVGIREYHRNNVEISLNLVDEYKKHNQWDSTGLNDFRNMAYEEISDNLSLADQGNLFKITLPTGMGKTLAAYNFAFRLRDKRLKNRGIPPRIIYALPFLSVIDQNYNVLSDIMELQGLTGHNILIKHHHLADPVYTMGKGEDEITYSPNASKLLIEGWASEVVVTTFVQLFETLIGWRNSCLRRFHNLAHSIIVLDEIQALPVSYWQLAQHVLEYMINNMNVDIILVTATQPKIFTGDMNPFELVNAEQYFGNMDRIAMKVDLFPRTVSEFADSIKDELQGQERKSFLFIFNTIASAKEFYQLLVKMVDEPVAFLSTGVVMKDRSLRIKDIKDKKYRFAVSTQLVEAGVDIDFDVVYRDFAPMDSINQAAGRCNRNGLGERRGVVNIIYLVRENKKRSYAGLIYNNTSLDITKRILKDKGMISESELLDLIDLYFQHAKDLGRASESFHLLEALQNLRFNSGDNPDAGVNDFRLIKQRGNRVNIFVELDREAEEVWLEYEDIVQHCEDFYQRQERFETIKKDFYQYVISVTVNEGMFLPPEFNNFCYVSKFQLKSYYDKNLGFDTSNYENIF
>NC_021184.1|WP_006521012.1|827468_828197_+|type-I-B-CRISPR-associated-protein-Cas5
MKKKVLIFDLYGDYAHFRKYYTTTSPLTFSIIPPVTLMGVLGAILGLSNQDNLYLKTLNEAGTKVGIQLMKPVKKFRMGMNLINTKNDYWVPRHRNEGARTQIKYEFLKDVAYRIYVSMDNEELLNQLEYNVSRHKCVYTISLGLSELLADFSFVDMQDFNWRENDGKFIDIVTAVPMNDVLQGGIDISPGERYLKENMPIKMDSNREVTQYSEMLTETMGNHIKLKINGFWESHGLNINLL
>NC_021184.1|WP_157872714.1|826495_827458_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MSMSISNRSEVLFIYDCTFSNPNGDPLDANKPRIDEETGRNIVTDVRLKRTVRDYFHNLKGEEIFIRDITDDDDHLQDAKMRAEDFLADKKDKSKLSLKEMRQVIRQNILTSCIDVRLFGATIPIEKSSKEKSSVTLTGPVQFKMGQSLHRVKLQFIKGTGAFASGSERTKKTFREEYLLPYSLICFYGVVNDCAAEHTGLTDDDVNNLMDALWNGTKNLISRSKAGQQPRLLIRVAYKEKFYHIGELDKLVAFQSDLNDEEIRDIEEGFLDFGKLIGILAENKDKIDYVEYAMDKRVRPKQKLKEMLSEHGLNVRELIY
>NC_021184.1|WP_006521010.1|824742_826512_+|TIGR02556-family-CRISPR-associated-protein
MITAVRELGTFALNKSGKDSLSALTEVINADNYPYMLVIELEEYEPCEFICVSVEDMNAGGAGRYIYRQGSSRGSNYSPTAIITDIKKTLPIKIIGWFNSVSKQKLMFSKEEQGYLKIIKKSLEKNRAKIESEIMEKLQDIGKNCGLTLKIGGKYLSELVIFRKAFTQLVSAKEDSISAPDKLCSLCGKRKIKVSAGAPAYKFYTIDKPGMISGHFIEEKSWRNYPVCQECSRALDEGKRITERNLKFSFYGLSYALIPKFLFGKPSEIILKIITGNRMDKNIKIKTETGQKLVKTEDSILHILAQEQDNLMYNFLFSKKSNNAERILLLVEDVLPSRLRALFAAKGKVDSVFVDDPFHLGKVRNFFAKSDEGKRDNDLDKYFLEIIDKTFKGLPISIPFLATHFMREIRRDFNNQEGALFKVGNAIQTVMFFVDLSMLTPKEVIMAETIFDPVFKKYEAQLDNREKRGIFLLGSLTKMLLNIQYTTRHSQPFLSQLMGLKMDERSIKGLLPKVTNKLLEYKRLDHKKAQLAEVISQYFLESSANWRLSVDELNYYFVCGMNLYKEINVVLYGQEEVKEEEEEVDVDVD
>NC_021184.1|WP_006521009.1|824293_824548_-|hypothetical-protein
MLQSNKQIISRNNQWKIYNVWQSSIRNPVEIDPLKTFQWYCDAWAMASTQNSDWLRKKVVKEKVWRLQKMRQAFALLGEVYERP
>NC_021184.1|WP_006521007.1|823371_824136_+|CRISPR-associated-endoribonuclease-Cas6
MYAYIKLRMDPSSPAIPIHYNYLIQSAVYAALPEDMAVRLHDDGFKSGKRNFKMFAFSRLLGRFSLDRTAGTITFPEGVSLVISSPDTGFLLALINNLLTKSTVRLGQSLFYVEEVRFDEQKAEAEVLTVRTLSPVVVYSTLLRPEGGKYTCYYQPGEREFDRLITTNLAKKYEAFHGLRPPEGEIKVQPLDRPRLHVTTYKGTVVKGYTCRLKLSGPRELLQMALDAGLGGKGSQGYGCVGKIERLKAGKTKP
>NC_021184.1|WP_157872871.1|822687_822957_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MTNIKPSTAIRHDYNSFSKLCHETQAPVVVTKNGEADLVVMSHEAFQKMMARQRLGRMLSEVDRQIAAGTPMRDFEETFTAIKKRIDSE
>NC_021184.1|WP_041285180.1|834508_835051_+|hypothetical-protein
MKRYVTIFLLGMVLFYGVGCSNTTNNSNTTTSQIVSKKYIENKGYKIVSYDGIFEEYVLTKEKITQEPYIQEWAVQSFEPKKYLEKKITVEKFTVQNHPLDKWIPIGGLNNDIQSTGKTAIYVFVVDNKAIGGYSIPAVKEGKIKLADTMIWSVDGKHFSELNPHIDSEQWKKSWQEKFE
>NC_021184.1|WP_006521018.1|836206_836950_+|DUF2162-domain-containing-protein
MLWLQGGLLVATLILGIKTGLILGTSWLNRWWLIMISGIFGISLYGLVLAFSAHQQVLVMFLDRYTFVGSLLMAVLLIYLGLQQGPEQGCSSFRQPVEKALKLGFSLGHWKFILGFLPCPLCLAALSFSIILISPMVGMSLSELGRVIALLFLALVLVTSVAIRKIVQLVKFNPATIFNTLLLFIGILTLTFALTVPNFVQSMAMPLAPLTISSPHLVALVLVVMAGLGLWGYILYQISYVKDCDNQ
>NC_021184.1|WP_006521019.1|836946_837636_+|MotA/TolQ/ExbB-proton-channel-family-protein
MNIPGSEYLTKILHATSQSLLIPVVLGLLLFLVIAFTELGTFVAEGKRRKANKSVNMMEVFHNVGNIAPWQMKNLQQVIDSCSLLPRQKNLLTALLAKVNLSTEVKQLIARDILDQEEFRAKKVLGKTDLLAKLGPVIGLMGTLIPLGPGLAALGQGDVRGLSEAVIIAFDTTVAGIAVGAVAALISKVRRRWYEQDLSNMELLLELVVGGETLAVQENEAGPAVRRRS
>NC_021184.1|WP_052543922.1|837601_837934_+|DUF2149-domain-containing-protein
MRRGRLSEEEVDPLGGLGNLIDVMLVFSCGLMVALVLSWNLQNIIFAKVKPEEKQRLMQSIQKVINVERGQELEEVPQIQQGGGAGYQEMGTVYRDPKSGKLIMIEDGKE
>NC_021184.1|WP_006521021.1|837953_842693_+|cobaltochelatase-subunit-CobN
MFSRTYKLRKTAISIFLVLLALVVTLLIKVPVATADENVSTRVVMLIGSEGFLMPLVDAYDKLGNYPIDLKLFSSNDLVNEKKVQQFNQSLQDADVFLLEMIGGNGIQTVGPLLQDLPEEWKGKVLSTRSGSFPQYPQIDESQDSFLANYFKYGGVENMRRLVLHLASTYGQVTTGEQLDPINMPGRCIYHPDAEGLTFNVDGLYGTVCDAVYEAGNGATRGLVVNEVHRAVYDSVSAFVYQPDNMTRTLARLTVNQAVYDRGGDAPVFEAGDLYQTVAGAVYQAGQGDEGLQDFYNTVRQSVSEAVYQDGGSDAGLAIDMVYSALYDQAARDYLGDAQAMVYRAVYDALAGPELPGFDPAHVYQSVHDAVYLPTGGGGGIGLPPGTFDTLGGYLAWYKASGHFKEGAPWVGITTYDSFFKNSDSDMFLAVQRELEAGEANALLVFSDSSNRKTAFQDFFMPDGKRQVDFLIAAVGFNFIYGQPEEGIELFKQLNVPVMAPVYSSNLNEWQSNPAGISSEVAWQVAYPELDGRIEPVFMGGSTVVSVDESTGATIIKKVPLSDRVERLVGRALAWVNLQQKDNTDKKIALVYYNHHGGKDDIGASYLNSIASTAVILQALRDNGYRVEGELNPQAVEEMIRQRGRNVGSWAPGELDTLVQAGVLLLPVEKYLEWYATLPGELKAQVEKEWGPPPGNIMVYEGNLVIPGATLGNIFLGPQPVRGWGDDPSKIAHSPALPPPHQYIAFYFWLQKEFQADAVIHLGTHGTLEWLPGRSVGLGEADWPDVLMGDLPDIYPYIMNNPGEGTQAKRRGYAVTIDHLTPPMIQPGLYGALDELQQLVLDYQYAVSGGNTTRATNLQEQIIEKIKANNLDQDLGLNLETADFAQVASLLHDYLEELSTELMPYGLHTFGLPPQGEMLDLMVNSIINYDVAAREGSREEIRERLLLTTNEITNLLRALSGEFIEPGLGRDPVRVPDALPTGRNIVSFDPRMVPDAAAWKTGKEAADQLLEKFYAEQGRYPETVGVVLWAIETMRTQGESVALILRLIGTEPVWDKSGRVSTVKLTPLEELGRPRINVLVTISGLFRDTFSHTVGVLDEAFRQVALLEEDPENNLVRKTYLTLRDKLREQGLSEQEADDLAQARIFGDAPGTYGTGVSELGQATSAWEDSQDLVDTYMNRMSYVYGKTAYGVPAQDAFREILKSVDLVTQVRDSLWGVLDNDDVAQYLGGLKLAAEAASGNKVQSYIVNTRTGSPRVQTFSEFVGTELRSRLFNPKWIEGMLKEGYAGSREIGNHVANMFLVDATLEGIDDWAWQQIAETFVFDEKIMSQLDPFVMQSIIGWNLEAARRQMWQADQETLSKLADNYIQTVTQYGVVCCHHTCSNIVFNEWLASYATVDSEAMDKFKEVFYTSTDQKLNIASKQNQDQDHHAPSPHSSSSRKASPEPVEQVEQLQMNVEEPVEQVEQPQMDIEEAEPQSTPSPGAAAAPSQSQQLAQLSTPVGDKPAQHNTQQNIRTETQQSTQQETAKPEQGQKNVKAYEIKQESAHQSSSTGTKAVSFIALLAALGLVATFFKGYISK
>NC_021184.1|WP_006521022.1|843057_844275_-|IS256-like-element-ISDgi1-family-transposase
MQAMQDKTIKELAKDCRTVEDVHEMLKNLFKDTLQQIFEAEIEEHLGYKKHSIEGNNTGNSRNGYNKKTIQTKFGKTEVEIPRDRNGEFEPRIIGKYEKTSNQLEDQIIAMYAKGMSTRDIEDHMRDIYGIDVSPTMVSKITDKILPMIAEWQSRTLDRIYPIVFLDAIHFKVRKDNRIINKAAYSVLALNMAGQKEILGIWIGENESASFWLGVCNDLKSRGVQDILIACKDGLSGFSEAINTVFPKTEIQLCIIHQIRNSLKYVPYKEQKELMADLKQVYQALTLEEAELAFEIFKENWGKRHPIIIRSWEKNWLELTAYFKYPYEIRKMIYTTNIIEGYHRQLRKVTKTKTAYPTDDALKKIIYLATVEAAKKWTMPVKDWKNCISQFAIYFGDRIESEMAI
>NC_021184.1|WP_015617913.1|844367_846104_-|IS1634-family-transposase
MYLKKTYRKESGRTYLVIAQKYRNPVTNISTDRTIKSLGYLDELEKEYDDPIAHFKEVARKMTEEENKKKKLTLTINMDEQLVQGADDRKNFGYVAILKIYHELGLHRFFNNRARNESFKFNTNSIMMLLVVSRLLSPGSKKKAFEERRRYFERFNFSLADVYRALSHFAKIAKEFQRYLHGQIAEKYGSNTKTIYYDVTNFYFEVDEADELRKYGRSKEHRHDPVVQMGLAMDADGIPLHYELFPGNKLDKETFRSVIGEVRKNYGTGRIVVVADMGIITGDNIYYLTGGKNSNGYVFSFSVRGGTDAFKNYVLDNEGYVGTDGKPAGEDAEFKIKSRRIARDINVTMKSGKTAKKTVYEKQVVFWAKKYADKARAERKEVVKKALDLVADPKKYNKAITYGAAKYVKHLEFDKETGEVLEGKQRPYFDSDKLAQEEMYDGYYAIVTSELHMSDGEIIDTYRGLWEIEETFRVTKGTLEARPVYVSREDRIGAHFLTCFIALIILRLIQKKTERRFSAERIVECLNRIACSNEQDNLYMFDYRSEISDAIGNALGIDFTKKRLRLSDIKNILANSKK
>NC_021184.1|WP_006521024.1|846745_847078_+|hypothetical-protein
MNKMEIMRKIEQEEIVIIQEEVKVDFDNRQQSPIGFQWHNRHYEVLEVLTMSKDLCENLNYLVLTNKGIFKLILVKDNNQLTISKSKWVLNFQVMEDIAYPNKRVNAVIH
>NC_021184.1|WP_006521025.1|847143_848706_+|ABC-transporter-substrate-binding-protein
MQRKYLLLLLLGCLLCVFIAAGCGGEDDNDAAADRQDTSGQQQLIVAISTDVSNWDLDKFPEGDSRFPWSQIYETLVRLDTDLKEQPGLAVSWEPSEGGKVWTFHLRKGVKFSDGSPLNAEAVVYSYSSRADVVKRKMLPVQSIEPVDEYTVKFTCSQPTPLPSYFTHVAWPVMSLMSLDDGGAFKGPIGTGPYKLDKHLTDQEIVMVRNEHYWGEPGTLDKIIFKVIPDASARSMALQSGQVDMALKINEFDIENLESQAGINIYKKPSTFTDFLQFNTEKSPFDDVNVRRAVSYTVDSEKIVQQMLAGIGVPAKGRPISPVMQFSKSDLKIEPDIQRARDLLAAAGWKDTDGDGILENGGQPLQVSMLLAPWSPRQKIEAEAIQGQLKEVGIDLKLTVMETGALTAAEKAGEFDILLRSGYYTWGSYPHHFKIHTTNHMYGHWDNSEYDRLVAQAEAALGENEKKELYKKLQQIIIDQLPALYTIHEEKVVATRDWVKNYQITSEDPWLNLAGVKVEK
>NC_021184.1|WP_006521026.1|848724_849327_+|methyltransferase-domain-containing-protein
MDTHREWFNKKAETWDNVVLEAERCHRLFDLITVLDIQRDSRVLDVASGTGILIPWLLEIVGTGGKVVAVDFAEKMIDVARGKYGDTGVDLLVADVQQLPFEDNSFDEVICNSAFPHFAGKLDAMREMSRVLKSGGRLTICHPAPREELNNFHRCLGGVVGNDMLPSESEMRQMAVKAGLDSVFIKDGPATYLFTCRKVR

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Crispr_ID: NC_021184_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_7

868929-869043

Unclear

Consensus_repeat	Method
GTATGGGGACACACCTTCTTAGCTTGGGTAGATCCCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021184_7

>merge|NC_021184|7|868929-869043|CRISPRCasFinder
GTATGGGGACACACCTTCTTAGCTTGGGTAGATCCCTTACTTTTGAATAAATGCACGAAGGAATGTCCCCAATTGGTGTATGGGGACACACCTTCTTAGCTTGGATAGATCCCTT

>NC_021184|7|7|868929-869043|CRISPRCasFinder
GTATGGGGACACACCTTCTTAGCTTGGGTAGATCCCTT	ACTTTTGAATAAATGCACGAAGGAATGTCCCCAATTGGT
GTATGGGGACACACCTTCTTAGCTTGGATAGATCCCTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_006521044.1\|863136_863361_-\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006521048.1\|864997_866341_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006521042.1\|862190_862589_-\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	unknown	unknown	gnl\|CDD\|379205
NC_021184.1\|WP_006521051.1\|870119_872024_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319774
NC_021184.1\|WP_157872718.1\|866456_866606_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381054
NC_021184.1\|WP_006521047.1\|864459_865005_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|180707
NC_021184.1\|WP_006521058.1\|878665_879394_-\|membrane-protein	unknown	unknown	gnl\|CDD\|377194
NC_021184.1\|WP_006521052.1\|872344_873439_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NC_021184.1\|WP_006521059.1\|879489_879831_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224916
NC_021184.1\|WP_006521046.1\|864104_864296_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006521053.1\|873422_874220_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223629
NC_021184.1\|WP_006521050.1\|869667_870087_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_021184.1\|WP_006521057.1\|877603_878611_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
NC_021184.1\|WP_006521055.1\|876115_876817_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226359
NC_021184.1\|WP_006521043.1\|862585_862849_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|273625
NC_021184.1\|WP_006521056.1\|876819_877584_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_021184.1\|WP_006521049.1\|866658_868911_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|379663
NC_021184.1\|WP_157872717.1\|863320_863575_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372378
NC_021184.1\|WP_006521054.1\|874461_875475_-\|tungstate-ABC-transporter-substrate-binding-protein-WtpA	unknown	unknown	gnl\|CDD\|235236
NC_021184.1\|WP_006521045.1\|863808_864108_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_006521057.1\|877603_878611_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	8.25423e-34
NC_021184.1\|WP_006521042.1\|862190_862589_-\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	gnl\|CDD\|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	1.34616e-14
NC_021184.1\|WP_006521051.1\|870119_872024_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319774	cd02079, P-type_ATPase_HM, P-type heavy metal-transporting ATPase. Heavy metal-transporting ATPases (Type IB ATPases) transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. These ATPases include mammalian copper-transporting ATPases, ATP7A and ATP7B, Bacillus subtilis CadA which transports cadmium, zinc and cobalt out of the cell, Bacillus subtilis ZosA/PfeT which transports copper, and perhaps also zinc and ferrous iron, Archaeoglobus fulgidus CopA and CopB, Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase, and Escherichia coli ZntA which is selective for Pb(2+), Zn(2+), and Cd(2+). The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This family belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_021184.1\|WP_157872718.1\|866456_866606_-\|hypothetical-protein	gnl\|CDD\|381054	cd19588, serpin_miropin-like, serpin miropin and similar proteins. Miropin, the serpin from Tannerella forsythia, is thought to contribute to the virulence of periodontal pathogens by inhibiting neutrophil serine proteases. Miropin broadly inhibits serine endopeptidases (SEPs) including trypsin, neutrophil elastase, pancreatic elastase, subtilisin, and cathepsin G and cysteine endopeptidases (CEPs) including papain, calpain-like peptidase Tpr, and gingipain K through various reactive-site bonds. This is achieved by offering several target bonds of the RCL for cleavage within a bait region, instead of a single RSB as found in canonical serpins. In addition, promiscuous inhibition is facilitated by the capacity to insert strands deviating from the canonical length into the central sheet A, while keeping the prey peptidase bound and inactivated. The structural adaptation of miropin to provide a relaxed inhibitory specificity, which allows for formation of inhibitory complexes using different sites, is unique among serpins. SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate blood coagulation cascades. Non-inhibitory serpins perform many diverse functions such as chaperoning proteins or transporting hormones. Serpins are of medical interest because mutants have been associated with blood clotting disorders, emphysema, cirrhosis, and dementia. A classification based on evolutionary relatedness has resulted in the assignment of serpins to 16 clades designated A-P along with some orphans.	9.56988e-11
NC_021184.1\|WP_006521047.1\|864459_865005_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|180707	PRK06811, PRK06811, RNA polymerase factor sigma-70; Validated.	1.38976e-49
NC_021184.1\|WP_006521052.1\|872344_873439_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.88131e-110
NC_021184.1\|WP_006521059.1\|879489_879831_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|224916	COG2005, ModE, N-terminal domain of molybdenum-binding protein [General function prediction only].	2.69572e-19
NC_021184.1\|WP_006521058.1\|878665_879394_-\|membrane-protein	gnl\|CDD\|377194	pfam04016, DUF364, Putative heavy-metal chelation. This domain of unknown function has a PLP-dependent transferase-like fold. Its genomic context suggests that it may have a role in anaerobic vitamin B12 biosynthesis. This domain is often found at the C-terminus of proteins containing DUF4213, pfam13938. The structure of UnioProtKB:B8FUJ5, Structure 3l5o, suggests that the protein has an enolase N-terminal-like fold and this Rossmann-like C-terminal domain. Structural and bioinformatic analyses reveal partial similarities to Rossmann-like methyltransferases, with residues from the enolase-like fold combining to form a unique active site that is likely to be involved in the condensation or hydrolysis of molecules implicated in the synthesis of flavins, pterins or other siderophores. The protein may be playing a role in heavy-metal chelation.	2.78574e-05
NC_021184.1\|WP_006521053.1\|873422_874220_-\|ABC-transporter-permease	gnl\|CDD\|223629	COG0555, CysU, ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones].	5.82621e-69
NC_021184.1\|WP_006521050.1\|869667_870087_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.31117e-22
NC_021184.1\|WP_006521055.1\|876115_876817_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226359	COG3839, MalK, ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism].	9.63634e-83
NC_021184.1\|WP_006521043.1\|862585_862849_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|273625	TIGR01439, Uncharacterized_protein_Mb2626, looped-hinge helix DNA binding domain, AbrB family. This DNA-binding domain family includes AbrB, a transition state regulator in Bacillus subtilis, whose DNA-binding domain structure in solution was determined by NMR. The domain binds DNA as a dimer in what is termed a looped-hinge helix fold. Some members of the family have two copies of the domain in tandem. The domain is found usually at the N-terminus of a small protein. This model excludes members of family TIGR02609. [Regulatory functions, DNA interactions].	1.9823e-07
NC_021184.1\|WP_006521056.1\|876819_877584_-\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.7193e-57
NC_021184.1\|WP_006521049.1\|866658_868911_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|379663	pfam14620, YPEB, YpeB sporulation. YPEB is a protein that is necessary for the functioning of SleB during spore-cortex hydrolysis.	4.97853e-05
NC_021184.1\|WP_157872717.1\|863320_863575_-\|hypothetical-protein	gnl\|CDD\|372378	pfam12910, PHD_like, Antitoxin of toxin-antitoxin, RelE / RelB, TA system. This domain appears to be the N-terminus of the RelB antitoxin of toxin-antitoxin stability system or prevent-host death system. Together RelE toxin and the RelB antitoxin form a non-toxic complex. Although toxin-antitoxin gene cassettes were first found in plasmids, it is clear that these loci are abundant in free-living prokaryotes, including many pathogenic bacteria, and these toxin-antitoxin loci provide a control mechanism that helps free-living prokaryotes cope with nutritional stress.	2.47393e-22
NC_021184.1\|WP_006521054.1\|874461_875475_-\|tungstate-ABC-transporter-substrate-binding-protein-WtpA	gnl\|CDD\|235236	PRK04168, PRK04168, tungstate ABC transporter substrate-binding protein WtpA.	1.68539e-156

>NC_021184.1|WP_006521049.1|866658_868911_-|S-layer-homology-domain-containing-protein
MRRKALCFSVVLLFGSLLMSTAAAAEQTASQIVIKEVTVTEAIKLPPTSEEKKDSPRISEDEALKIIKSVFPEIIGESKPDMQLDFEPYQDRNIWRIHYYERMYHGPGMPAGYSVSLDADTGEILNMSWRNNTPAETKGIIQKQEAQKIAEQFVQKLQPERFKSMQLQKSPTEHYYPLPNLDIVHRFYWARVENGIKVDYDGIRVSVDALSGKVVSFNMNWQPEVKLPAIGTPVPAKALTEKATNELGMALIYQVPYRNYAGKSPEAKLIYQLNTRELMFNATNGKAVDNQGKEKNIKDIRLFEDIPKISGVNNPPDSPGQRITVEKARSTAERFFRSLGIEGEVEMGGGGSSVGGPFGNQEFWSFEIAQKGSSRHYPGSQVGIDQTTGRVVNYYEYGPEMQAETGSPKISREEALAKADAFIKNVAPEYSPYLAPEKNQVDMYPMGHEQGYSFHFYRVVNGIPFPQDGIHIGISSDGKIRDYHCEWHKVSFPAVQNVIAPEEAASKWLELSSLQVNYFIPREGEKPGSQAILVYRPDNDGFSAIDALTGKPVTNDGQPVNKTSGNGYDYKQSWAAQYLEIVAGSGILPSPEQFSPTGAVKKRDVARLITATMGNYYDYNEKREQQFRDVNLEDPDFNAIQAGAIMGIYDKGGNFNPEQPVTRLTLARWMVNAMGYAEIAKINNNIASSYKDIASLSATDRNYIGLAQGLGIMRGDETGLFKPSDSVTWEELAAVAINSAPKMRNKNGTW
>NC_021184.1|WP_157872718.1|866456_866606_-|hypothetical-protein
MTGDGIKNLNDSLTVLGMEEAFTNTADFSGISNGVHISRVLHKGITCRL
>NC_021184.1|WP_006521048.1|864997_866341_+|hypothetical-protein
MNEDKMLTILNNLDDDLIEKEIDNLMDGVECNMESINKKAHKKLDKYNRKIKFRKQLPYVAAICACFICINTVYADDISEAVKRFFNKTPVYSTMVDGSAYYLKDSLVLDDNMVIDSFMVSEGRMDMKFTSKLGISILKDTRIIPKDNPNTQYVMGGYSEDNGKYTFSFMNGKEDNYNIKPFKSFDLIVGNKTYSISLDQAKSLDETQKLFASEATSNQIGLVDVGANSLEKDGKQAIQLIASFKNKDMKLSKFGRPVDSTVKTTFENLGEDGIVSTGTGLRTEDIYVTDESGTKYKLEVPADSNAFPVTTFVTDAAIDNKLTLKLPALIASYQKKVDSLKIIIPKEGEEILNRDVDMFAQKAVAKSIKRLSPTSAQLVFQLNTGNEKYVGIKSFHIDSKNILKASSEFSGDTAVMILEFNKDVDEINLDISWPKFVMNGNWTINMK
>NC_021184.1|WP_006521047.1|864459_865005_+|sigma-70-family-RNA-polymerase-sigma-factor
MEYSQAELVRGIRNKDSAAYEYMICKYTKTVFCLAYNILSESHSKEDIEECVADVFLDAWIKIAEFDEEKANFRTWLLILTKYKALTYRRKKRLSNILDIEDADIKNDVNLEKLVLLRQDQEQVIKIINSFQKIDREIFVRRFFLGEKISDLAKAFNLSRAAVDNRLLRGRKIIKEGLQYE
>NC_021184.1|WP_006521046.1|864104_864296_+|hypothetical-protein
MRRVELIRSIAGLTRRQTKEAQDGLIEWLWKIAETDTSAYCRQECLSALYTDLGQEKTLEQFV
>NC_021184.1|WP_006521045.1|863808_864108_+|hypothetical-protein
MMQTWPRIFTDPAAAVQWLDETYFKLSSPMARENLVYAVGEVAKLNGAIHPAVTVWLWRVQEQEPDPDYCFDQLITIYELGEAKALEEIDGLYSGITSP
>NC_021184.1|WP_157872717.1|863320_863575_-|hypothetical-protein
MLDQIDIAVNGPTLDEAIEELIRELKTYAEDYRDNMSLFLNAPNRKGHFPYILRVWLCDNTRKLNHFWRFKYAPKIWSPEKVLR
>NC_021184.1|WP_006521044.1|863136_863361_-|hypothetical-protein
MPPKFGHLKKYCDKTGWILIRDIDHWYYEKVLANGDVLRTRVSHAVSKEIPGNLWKKILRHQLKITEEEFWKSL
>NC_021184.1|WP_006521043.1|862585_862849_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MNLAKVSANGQITVPVEIRRKLMLKEGDKILFIERENGEIVINNASATAILKAQKAFKDVAEAIGIKNQDEVQALVDEVRYGKDSKQ
>NC_021184.1|WP_006521042.1|862190_862589_-|putative-toxin-antitoxin-system-toxin-component,-PIN-family
MKVLADTNILISALLWPHSKPAATLLHAARYHELVLCDRNIFELRDVLGRKAPYALADVEVFLAELAYDLVPAPEYPQKLISDPKDQPILNAAIVADVDIIISGDKHFLKLNMERPRVMTAAQYLEWIETEQ
>NC_021184.1|WP_006521050.1|869667_870087_+|winged-helix-turn-helix-transcriptional-regulator
MKFVEEMTDELLHFYNGFASWESSVIRSSDLSVSEAHAIEVLGQYGKMNMKSLAQKLGVTTGTTTVTVDRLEKKDYARRESSREDRRVNLIVLTDKGMKAFEEHHQYHLCLTEQMLSTLSDAEIEQLLNTLKKINAETF
>NC_021184.1|WP_006521051.1|870119_872024_+|cadmium-translocating-P-type-ATPase
MIGRYANVSKYRELLQMREFYMVLLGSFLIITSYGLGERDYPVQANILSLLALAVLGGAIILGAVKGLLKRELNVDELVSLAMIASVLIGEYLSAAVVALIMVLGSLMEEFTAQKARSAVDALIRLNPGQATVIRDGAEVLVPVREIRLGDMVMIRPGDKIPIDGKVIRGSASLNQASLTGESLPVDKLTGDDVYAGSVSYSGMIVVEVSKVGGETTLGKLIKLVQDAESQKAPALRVTDHYAKYFTPFIIAISSAVYFFTGDLHRAITVLIVGCPCAFIISAPTAIVAALGNASKNGILVKGGAFLEELARIDAVVFDKTGTLTTGSMVITGTKPLNGVSDDYVLSMAAAAEKYSEHPLARAVLKAVEQRGLVVTEPESFNSIPGLGVEAVVAGKKIVVGALTPEERVAEGFLNAANINPGVKTLVVTENNSMIGEIYIRDNIRPGVRGLIKALQESGLKKIQMLTGDGNEVADHVAGACGIKEYRAELLPEQKLNHIKELQKSGYKVAMIGDGVNDAPSLAAADIGIAMGAMGTDVAMEAADVALMGDNLARLPYLLQLGYSTMKTINYNIAFAVLFNLLALLASGAGLLNPVMGAITHNIGSVLVVLNSARLIKFRLYMAGVEEQSVENCT
>NC_021184.1|WP_006521052.1|872344_873439_-|ABC-transporter-ATP-binding-protein
MLEIRDLNVNLFGFALRNIQLTINQGEFFALLGPTGSGKTVLLETIAGIKQPSGGRFFFHRRDVTHLKPEQRNISIVYQDYALFPHLNVLANIQYGLRFKKKRNVAGKPEMLHMLVEMLGIDHLLKRYPDNLSGGEKQRVALARALIVEPDILLLGEPFSALDTNTKETVQAEIKALHSALKITTLMVTHNFSEVFSLAERVAIIKNGEVQQVGTTEEVFKMPNSQFVAEFVGMKNVFALHQVNGKAMLGDVLQLDMQVPEEQSAGKHPTTGGNNKYFIGLRPEDIVVGNGALKTDYQLTGTVLTISNNGVYSEVKVQSGQVNFTAYITPNRFFELGLRENKTVTLGFDRKNINFIKGQACATG
>NC_021184.1|WP_006521053.1|873422_874220_-|ABC-transporter-permease
MKLKTEKLYLTSAFLGLLILLFIMYPIINSLITTDGQILLQTLRDREVLAAIWNSIYTATITTMIVFIFGVPFAYFLARNEFRGKRLVESIIDIPIVIPHTVVGIILLTVLSQQCWLGRLLENLGLEVVGTRIGIVTAMTFVSMPLLINAAKDSFAAISPKLEYVSRTLGATHMQTFILITFSVGWRGILTGMILTWARSISEFGAVIILTYHPMIAPTLIFDRFNSFGLEYSKPVSAILIAISLAIFIVLRVIAQRGVRDAGNT
>NC_021184.1|WP_006521054.1|874461_875475_-|tungstate-ABC-transporter-substrate-binding-protein-WtpA
MLKLSKKLLLLYLIIAIAFVAGCSGATDADNSNQPINEGQASSNLTGKLIIFHAGSLSVPFDQMEKEFELLHPGVDVQREAAGSRECAKKVTDLGKPADIVASADYAVIDNLLIPDFAEWNALFAKNEMVIMYSEHSKYKDEINSDNWPEILLREGVEYGHSDPNADPCGYRALMVWQLAAEHYQISDLYQKLDEKRPARNIRPKETDLLAMVESGALDYLFIYRSVAEQHNMPYVELPPQVNLSDLNQAEFYKQATVDTTGKQPGEVITQVGMPIVYGVTLIKNAPNQANAIEFLKFLLSKDKGLKIMEDNGQPIEDPLVIKGEEAMPEELREITG
>NC_021184.1|WP_006521055.1|876115_876817_-|ABC-transporter-ATP-binding-protein
MSFIRLQNITTPYCLKNITLDIKAGELVVFLGYTGAGKSTLLNVIAGLAGYQGEVYFNQQNMNNIPTEKRDIGYLLQDIYLFPHLNTFNNISFALRATGYPADKITTKVESMLDLLHIGHLKCRYPKDLSGGEKRRVGLARALIREPKILLLDEPLASLDPATAKSIRKEIKTLHSRLNLTTLYVTHDFTEARELADKIGVIANGRLEQIGSVQDIFYQPVIEIKEFIAACGH
>NC_021184.1|WP_006521056.1|876819_877584_-|ABC-transporter-permease
MIKLVKPEITINNLLYPLPICFFLTSWEILAHITQTPLFPPLSKVVIEFWFLLGDGILLESLGSSLIRVLIGYSLGSLAGLLVGILMGLNKVVERSLSPLISMLFPIPTLGWLPLLMLWIGINEALPVTLIFICAFFPVAYNTLTGIKGVQHEYIKTARTLGASPWFILWHVTLPMALPNIFTGLRLEAGMVWRTVIAAEMFAIPTGIGALLINAESLIRVDVILVCLVLLSMMCTIFERMFLWLEYKTTGTWR
>NC_021184.1|WP_006521057.1|877603_878611_-|ABC-transporter-substrate-binding-protein
MIKKLVILVIFSACLLILGGCNQAPATQDTGVNLNVAVEYTDHAAAFYFAQGKGLFEDAGFSVEDVNVYASGVGVAAAFTKGGFDVSYMCLVPAIYTYANGGVPIKIISGTHKDGYGLVVNASKIKDLRDLEKDDIKIANGPKGTTTDFIQMLLLEKENLNAKKVLANTVRMNGAKQLMALRNGQVDAVFVPEHFAAMAASFPGMKMLASSRDICPDMQGSVMVVTEDFLEKHPEAVENLKEINKKSIDLINTYPQEAALIIAQNLNINQSKVKEETKSPQANLEVTPELVAKSMTNLRSTPEISQQDVQTIINKMHALGYITKSFDAGEIMSVN
>NC_021184.1|WP_006521058.1|878665_879394_-|membrane-protein
MSLLEEAREKLRVIIDEAGLHSGEAIDIVSTRDLTAKEAIGRPDRTDFPLLKGKEVMMQATYRDCVGQAFTDQPAQFHGTLEEVLRLTFDTNHNRAVFVATLNAVMRYLGKVQGTDHCKDKEPRLCARQLPEYITQHYGQPKIAFVGYQPAMIEELVKHFKIKVSDLDPDNIGREKLGVLISGPDNTAKNIDWADIVLTTGTVLVNDTLAELERGKPVIFYGVTIAGLAALFSLPRVCFYGR
>NC_021184.1|WP_006521059.1|879489_879831_-|LysR-family-transcriptional-regulator
MYIVSKIWLNQNGKAFGDGPYDLLTGIDRLGSLRKAASEMGMSYNQAWHLIQTIEGRLGFSLITRQVGGNSGGGSTVTPKGRLLMERYKAFREESKEVLEQLYEKHFQQMFGT

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Crispr_ID: NC_021184_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_8

1373754-1373849

Orphan

Consensus_repeat	Method
GAAAAAATAAACGTGCCGGTACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021184_8

>merge|NC_021184|8|1373754-1373849|CRISPRCasFinder
GAAAAAATAAACGTGCCGGTACTCGAAGGCTGCCTGCAGGAAAGGGCGCCAATTAATAACGATGTAGAAAGGGGAAAGAATAAACGTGCCGGTACT

>NC_021184|8|8|1373754-1373849|CRISPRCasFinder
GAAAAAATAAACGTGCCGGTACT	CGAAGGCTGCCTGCAGGAAAGGGCGCCAATTAATAACGATGTAGAAAGGG
GAAAGAATAAACGTGCCGGTACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_006522632.1\|1362259_1362901_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006522645.1\|1374910_1375303_+\|cytidine-deaminase	unknown	unknown	gnl\|CDD\|180142
NC_021184.1\|WP_006522650.1\|1380192_1380894_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006522649.1\|1378723_1380061_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_021184.1\|WP_006522639.1\|1369064_1369349_+\|sporulation-protein-YqfC	unknown	unknown	gnl\|CDD\|131903
NC_021184.1\|WP_006522644.1\|1374618_1374906_+\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|260135
NC_021184.1\|WP_041285269.1\|1370651_1371620_+\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|376820
NC_021184.1\|WP_006522633.1\|1362960_1364337_-\|ArsB/NhaD-family-transporter	unknown	unknown	gnl\|CDD\|238536
NC_021184.1\|WP_006522640.1\|1369360_1370674_+\|sporulation-protein-YqfD	unknown	unknown	gnl\|CDD\|377731
NC_021184.1\|WP_006522652.1\|1382675_1383407_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_021184.1\|WP_041285270.1\|1375430_1376327_+\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NC_021184.1\|WP_006522648.1\|1378058_1378727_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_021184.1\|WP_006522636.1\|1366634_1367258_-\|sulfurtransferase-like-selenium-metabolism-protein-YedF	unknown	unknown	gnl\|CDD\|274630
NC_021184.1\|WP_006522651.1\|1381066_1382557_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|235136
NC_021184.1\|WP_006522647.1\|1376700_1377675_+\|magnesium/cobalt-transporter-CorA	unknown	unknown	gnl\|CDD\|213356
NC_021184.1\|WP_015617929.1\|1367309_1368350_-\|selenide,-water-dikinase-SelD	unknown	unknown	gnl\|CDD\|273100
NC_021184.1\|WP_006522638.1\|1368725_1368968_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006522635.1\|1365349_1366426_-\|CoA-transferase-subunit-A	unknown	unknown	gnl\|CDD\|224702
NC_021184.1\|WP_041284799.1\|1383402_1384617_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NC_021184.1\|WP_006522634.1\|1364535_1365348_-\|glutaconate-CoA-transferase	unknown	unknown	gnl\|CDD\|224968

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_006522645.1\|1374910_1375303_+\|cytidine-deaminase	gnl\|CDD\|180142	PRK05578, PRK05578, cytidine deaminase; Validated.	2.30262e-60
NC_021184.1\|WP_006522649.1\|1378723_1380061_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.07385e-33
NC_021184.1\|WP_006522639.1\|1369064_1369349_+\|sporulation-protein-YqfC	gnl\|CDD\|131903	TIGR02856, Uncharacterized_protein_YqfC, sporulation protein YqfC. This small protein, designated YqfC in Bacillus subtilis, is both restricted to and universal in sporulating species of the Firmcutes, such as Bacillus subtilis and Clostridium perfringens. It is part of the sigma(E)-controlled regulon, and its mutation leads to a sporulation defect. [Cellular processes, Sporulation and germination].	4.35347e-23
NC_021184.1\|WP_006522644.1\|1374618_1374906_+\|diacylglycerol-kinase	gnl\|CDD\|260135	cd14266, UDPK_IM_PAP2_like, Integral membrane undecaprenol kinase domain co-occurring with type 2 phosphatidic acid phosphatase-like domains. This bacterial family of homo-trimeric integral membrane enzyme domains catalyzes the ATP-dependent phosphorylation of of undecaprenol to undecaprenyl phosphate. They sit N-terminally to phosphatase domains that are members of the type 2 phosphatidic acid phosphatase superfamily, and the function of members of this domain architecture was determined to be undecaprenyl pyrophosphate phosphatases. The bi-functional enzymes might generate undecaprenyl phosphate via two mechanisms - the phosphorylation of undecaprenol or the cleavage of the terminal phosphate group of undecaprenyl pyrophosphate.	4.71396e-31
NC_021184.1\|WP_041285269.1\|1370651_1371620_+\|PhoH-family-protein	gnl\|CDD\|376820	pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.	1.674e-138
NC_021184.1\|WP_006522633.1\|1362960_1364337_-\|ArsB/NhaD-family-transporter	gnl\|CDD\|238536	cd01116, P_permease, Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.	3.27468e-130
NC_021184.1\|WP_006522640.1\|1369360_1370674_+\|sporulation-protein-YqfD	gnl\|CDD\|377731	pfam06898, YqfD, Putative stage IV sporulation protein YqfD. This family consists of several putative bacterial stage IV sporulation (SpoIV) proteins. YqfD of Bacillus subtilis is known to be essential for efficient sporulation although its exact function is unknown.	4.0696e-144
NC_021184.1\|WP_006522652.1\|1382675_1383407_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.5692e-111
NC_021184.1\|WP_041285270.1\|1375430_1376327_+\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	9.50065e-171
NC_021184.1\|WP_006522648.1\|1378058_1378727_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.57738e-74
NC_021184.1\|WP_006522636.1\|1366634_1367258_-\|sulfurtransferase-like-selenium-metabolism-protein-YedF	gnl\|CDD\|274630	TIGR03527, selenium_YedF, selenium metabolism protein YedF. Members of this protein family are about 200 amino acids in size, and include the uncharacterized YedF protein of Escherichia coli. This family shares an N-terminal domain, modeled by pfam01206, with the sulfurtransferase TusA (also called SirA). The C-terminal domain includes a typical redox-active disulfide motif, CGXC. This protein family found only among those genomes that also carry the selenium donor protein SelD, and its connection to selenium metabolism is indicated by the method of partial phylogenetic profiling vs. SelD. Its gene typically is found next to selD. Members of this family are found even when selenocysteine and selenouridine biosynthesis pathways are, except for SelD, completely absent, as in Enterococcus faecalis. Its role in selenium metabolism is unclear, but may include either detoxification or a role in labile selenoprotein biosynthesis.	1.06287e-67
NC_021184.1\|WP_006522651.1\|1381066_1382557_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	3.94882e-48
NC_021184.1\|WP_006522647.1\|1376700_1377675_+\|magnesium/cobalt-transporter-CorA	gnl\|CDD\|213356	cd12822, TmCorA-like, Thermotoga maritima CorA-like family. This family belongs to the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. Members of the Thermotoga maritima CorA_like family are found in all three kingdoms of life. It is a functionally diverse family, in addition to the CorA Co2+ transporter from the hyperthermophilic Thermotoga maritima, it includes three Saccharomyces cerevisiae members: two plasma membrane proteins, the Mg2+ transporter Alr1p/Swc3p and the putative Mg2+ transporter, Alr2p, and the vacuole membrane protein Mnr2p, a putative Mg2+ transporter. Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.14954e-104
NC_021184.1\|WP_015617929.1\|1367309_1368350_-\|selenide,-water-dikinase-SelD	gnl\|CDD\|273100	TIGR00476, selenide_water_dikinase, selenium donor protein. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements: SelC is the tRNA itself, SelD acts as a donor of reduced selenium, SelA modifies a serine residue on SelC into selenocysteine, and SelB is a selenocysteine-specific translation elongation factor. 3-prime or 5-prime non-coding elements of mRNA have been found as probable structures for directing selenocysteine incorporation. This model describes SelD, known as selenophosphate synthetase, selenium donor protein, and selenide,water dikinase. SelD provides reduced selenium for the selenium transferase SelA. This protein itself contains selenocysteine in many species; any sequence scoring well but not aligning to the beginning of the model is likely to have a selenocysteine residue incorrectly interpreted as a stop codon upstream of the given sequence. The SelD protein also provides selenophosphate for the enzyme tRNA 2-selenouridine synthase, which catalyzes a tRNA base modification. It also contributes to selenium incorporation by selenium-dependent molybdenum hydroxylases (SDMH), in genomes with the marker TIGR03309. All genomes with SelD should make selenocysteine, selenouridine, SDMH, or some combination.	5.53352e-147
NC_021184.1\|WP_006522635.1\|1365349_1366426_-\|CoA-transferase-subunit-A	gnl\|CDD\|224702	COG1788, AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism].	3.2849e-50
NC_021184.1\|WP_041284799.1\|1383402_1384617_+\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	2.76543e-77
NC_021184.1\|WP_006522634.1\|1364535_1365348_-\|glutaconate-CoA-transferase	gnl\|CDD\|224968	COG2057, AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit [Lipid metabolism].	6.56605e-36

>NC_021184.1|WP_041285269.1|1370651_1371620_+|PhoH-family-protein
METRIIIDDIGAAAEIFGKHDENLSLLESSLGVKMVARGEELVIMGQREQVEKTREIIEQLQSYYQAGNRLTRHEINYAIKSLNSGKAGALAGLARDVVLVTARGKKIKPKTVGQQRYIEKLLKHDVVFALGPAGTGKTYLAVVMAVRAQRNRTVNRIVLTRPAVEAGEKLGFLPGDLQEKVDPYLRPLYDSLYDVLGIENTQKYLERQVIEIAPLAYMRGRTLDDSFVILDEAQNTTPEQMKMFLTRLGFGSRAVITGDETQVDLPRGQQSGLVHARRVLDGIEGIAFHHFTGEDIVRHPLVQQIVRAYEEKGALAEKTEV
>NC_021184.1|WP_006522640.1|1369360_1370674_+|sporulation-protein-YqfD
MFLKILNYLDGYVTITLPEECLEKFVNMATTRGIYLWGITNAAGNQVALNARLRDVQPLRHVARMTRCRFHIINRSGLPFFIGKLRRRRALLGGALCFVIALYALSSFIWFIDITGNQSVTEDKIARVAREAGLYRGAPKRSLDTAELEKTIMQQVNDLAWVGVSVDGTRVLIKVVEKVLPPDNGEHPVDIVALKDGLIKEILVLSGHPLVREGDTVTSGQVLISALIPPPEIEEESKPNAAEGEAEKEQQLTLQYVHARGIVRARIWYDVYNEIKLEEQVTKPTGSEITKLCMKIGGKEIILMGPHQVPYVHYTEHRDVKRLPEWRNIKVPVEVITVKYTEQGTYTNKLSRSEARRLAETQALDELRSQMPSGAKILNTQVREVKTAGEEDIVRVRVQVETLEEIGMEKPHQQDGGGSGIVDPKHGNQADGNQNNH
>NC_021184.1|WP_006522639.1|1369064_1369349_+|sporulation-protein-YqfC
MAWRDLKNKVKRQFSDVLDLPGDIMLDLPKIVLVGNLQVFIENHRGIQEYNPRLVRVVVNDKVIEVTGENLTLRNIMPDEICVEGQITGLIFLS
>NC_021184.1|WP_006522638.1|1368725_1368968_+|hypothetical-protein
MKQDAEELGATLKGSFGDEVDVKFVDVSTEALKEYPNIESILPRVRLPLTVINGEPRFHGGISAEVISDALQNIKKEQSN
>NC_021184.1|WP_015617929.1|1367309_1368350_-|selenide,-water-dikinase-SelD
MTNKTVRLTSLAKTPGUAAKIGPHTLSQVLRQLPVSQDPNLLVGLNTSDDAAVYRLNEHQALIQTVDFFTPMVDDPYLFGQIAAANALSDIYAMGGQPLLALNIVCFPDCLPIAVLEDILKGGADKVVEAGGIIAGGHTVRDDEPKYGLAVAGLAPPGGIISNATARPGDRLVLTKPLGTGIINTAIKADLLSPEAAKQAAQCMSALNKEASASMQRYNASACTDITGFGLLGHAAEMAAASQVSLEICFSAVPLLPETIEMARMGIIPGGAYDNKEYLIGKVTLDNSLRPEEQMILFDPQTSGGLLIAVPGSLADRLVAELAGQGTPSAVIGQVLPIQDKLISVI
>NC_021184.1|WP_006522636.1|1366634_1367258_-|sulfurtransferase-like-selenium-metabolism-protein-YedF
MNHKLVDCRGLACPHPVINTKKALEEAGVDTVTTIVDNDVARQNVVLFAKNAGYQVNEQPKEGFYHLTITRIGAQATANQTNESAAPTPAAVTPTVGPVYFITTNALGQGSPDLGQVLMKSLFTTLVAMDPPPAALLFLNTGVFLTCAGTPVQEQLEKLHTHGTAVLSCGTCLEYYGIKEKLLLGDISNMFEINNWLNKPHKAITIA
>NC_021184.1|WP_006522635.1|1365349_1366426_-|CoA-transferase-subunit-A
MYWTGFTPDEAREILVNKDKSKKDKRMGLAEAINTFVKDGYNIGIAGFVNSRQPVAAIHEIIRQKKKDLTLSFQSAGLALEYLAGAMALNPALCSIKRMEFAYWAHESFGISPLFRYLAESGKVELEDWSNFNMSARFKAGAMGIPFIPCRSPLGSDVMQANRSQIMDCPFTDDPVALLPAAHPHVALVHVQEADIYGNCKIQGPLFTCPEIAMAAGYTILTCERIVEHESIVSDPNRVNIPFFSVDAVVEVPFGAYPGNCHSHYYFDDKHIKELQTAGEAFRKGDRAPLEMYYDHYIYGVQNTAEFLSQIPYNQLQHIQQIEIRDFRLIRGVSRQDTGDSYKTSARSVKKLGTRGGI
>NC_021184.1|WP_006522634.1|1364535_1365348_-|glutaconate-CoA-transferase
MEILDYYADDFSPQEMIVVAGARILENNKVVFAGTGLPMVAITLAQLTHAAGIIPVFEAGAVGPRLTRGLPLSVGDSRTTSKAMYLQGLNSAFELAQRGFCDYGFIGGAEIDIYGNLNSTMIGEFPGDYQSPKVRLPGSGGASDMAASCERIIIIMVHEKRRFKEKLSYLTSPGFLDGSPGARKKAGLVGKGPYRVITTRALLGFDENTRRMKLLATMPGETVQSVQENTGFELLVDDNVYQFEPPTLEEIRLVREEIDPEGYFIKKKIK
>NC_021184.1|WP_006522633.1|1362960_1364337_-|ArsB/NhaD-family-transporter
MLENTSFWAIVIFLITYAVVVSEKIHRAVAAFAGASIIMLAKILTPDEAVHYIDFNTIGLLVGMMIIVGITRQTGLFEYVAIRTSKMARGEPLRVLASLALLTAVFSALLDNVTTVLLIVPVTLAITTKLKVNPLPFIITEILASNIGGTATLIGDPPNIMIGSATHLGFMDFLINLAPVVVVIYALTLYILLRIYKNSLQTTTQLQQAIMEINENNEIKDVVLLKKCIFVLSLTIVGFTLHQLVHLESSVIALAGASILLVITRFDPERALHSVEWPVIFFFIGLFVVVGALEATGVIESIAMFALDTTRGSILPAGLFILWLSAVASSFVDNIPFVATMIPLIKEMGRLGALENIDFLWWSLSLGACLGGNGTIVGASANLVAVGMAERNNVLVGFFQFFKISFPLMLMSILIAMVYLIAWYTYNTIMVILATLAPGLLLSLVLGQLNKRLNKDSK
>NC_021184.1|WP_006522632.1|1362259_1362901_+|hypothetical-protein
MSTTIIILIIAYVIISKIMGRDGRNLPQRPTGRPPGDVEQPRPDYASSRDEDVLLSGPWETSPRSEDGPLSGPWDISTRGEDAPLPGPWEQECSTGAENKPQSPTERENEPQFPRQQREQTNPAGDPPLVLGEQDRPRRLLNVAPQGDADHSDQPVAPLSRPIPATDPSRWRCNAGNPLAAALSSKNALVGSMIIGDVLNSRGGRIKKRPGQF
>NC_021184.1|WP_006522644.1|1374618_1374906_+|diacylglycerol-kinase
MKIHLLAAALVMAVGLLLQMPPIELAVLSITIFMVLAAEMFNTALEAAVDLVTPEFNLLAKIAKDVAAGAVLLTALNALLVAYLLIWPRLWDLMR
>NC_021184.1|WP_006522645.1|1374910_1375303_+|cytidine-deaminase
MKPEQLITMALKARLNAYVPYSNFAVGAALLTTGGNVYTGCNVENSSYGLTVCAERIALFTAVASGERKFTALAVVAGTEEYCSPCGACRQVLAEFGGETKVYLANRHGAYRETTVAELLPVAFSLKDIT
>NC_021184.1|WP_041285270.1|1375430_1376327_+|GTPase-Era
MHDPGFKSGFVTIVGRTNVGKSTLLNNMLGQKLTIMSDKPQTTRHKIQCVLTGADYQAVFIDTPGIHKPKHKLGEHMVGTALNALREVDVVLLLVEAAMPGPGDHYMLEQLKKVTGPVLLAINKIDLIKPDELMPIIAAFQKTGNFADIVPVSALTGENVQHLRQVIINYLPEGPQYYPDDMVVDRPERFIMAELIREKVLHLTSQEVPHSVAVVVDEVEQRSQELVAVRAVIYTERESQKGILIGKGGRMLKEVGKQARQELEALLGSRIFLELWVKVKKDWRNRDIDMRNFGLLEE
>NC_021184.1|WP_006522647.1|1376700_1377675_+|magnesium/cobalt-transporter-CorA
MIKTYFYDATRKLLVHDVDLTQKDLIQHEDDLLWVDLYDFENGHELNYLAGIFDFHYLAVEDCLQQSPRAKVDAYDKYYFFMLHALRYKEDSDEEIMLEQLNVFLSSNYVVTVHRRTLPTLGRMARECLSNRTKYMEEGSDMFLYHILDGITDEYFPILDRIDQRVDELEDQLYEQASKEITEEFLALKRTILSMRRAILPQKRMFSGLNGQFVFQISKESEPYYLDLVDHIERIIDSIDGFRDLLDGALETYYSIISARTNESIRVLAVISFIFMPLTFVTGFFGMNVPLPEQHSPWSTVAIAAGLMGVTAWMFLVFKMKKWI
>NC_021184.1|WP_006522648.1|1378058_1378727_+|response-regulator-transcription-factor
MYSVFLVEDEVNLCQILTTYLTKEGWTVRSFTDGQSALQAIEEQPHLWILDIMLPDIDGYQLLRSIKEASPEVPVIFISARDADLDRIIGLEMGGDDYLAKPFLPRELVLRAHRLLERVYKSRESKRSAIDLQPYTLDEERRIALQGCYNIELTSKEYDMVLFFAKHRGQALSRDQIINHVWGEDYVGTDRSVDDLVRRLRRKMPELRIETIYGFGYRMTVK
>NC_021184.1|WP_006522649.1|1378723_1380061_+|HAMP-domain-containing-histidine-kinase
MKKVSLTVKIWLALSLVSLMLYLITLLVMPSLIRSFFTDALMEPHKPPPPEQNIIKDKLPSYFSFRGINIRSLIILDDGTTIPVQAKQVVTASLIHEIRQNAESQQKSRQMYEYVDNQGSVRYVVQKNMIYGHDLYQISFFKKSEEDIFIKNLLLNFMVFAGITLIISWFCSLFIARYLTRPLIQMKQHVKRIANRNWHEPLDVKQEDEIGQLAGSIETMRQQLVRQDEAQQSILQNISHELKTPVMVIRSYAQAIQDGVYPKGDLAGSIQVIDEEGVRLEKLIKQLLYLTRLDYLVTREQAYQQIQLDKLVEKTLQLFYLQRPEIIRQLDLQPVIIAGSEETLRVMIENLLENHLRYADSRIEITLGLNIEQTEIWLCFWNDGSRIEPHIYDQLFQPFHKGREGKFGLGLTIVQRIVRMYKWQIDLSNERDGVSSKVKIPLSHS
>NC_021184.1|WP_006522650.1|1380192_1380894_+|hypothetical-protein
MSNWKTKVLSIVLGFSVLVPTASFAADTVTAPVDLPSNAKFNYHQRFDGEQGLSAQDNILGLVSKYAPDNMEEWQSVIAEREQLMSELKEQAPEQRPILSDEMKEKLQAVREAVKNGTMTQEQAAEELKELGLEKAGEIKQRPELSDEVKEELEAVREAVKNGTMTREQASEEFEKLGLQGKRDLPNQNNIMVQLDSAVESGDESTIKDLLAQLLEQMKEKNQQLSTKLSEIN
>NC_021184.1|WP_006522651.1|1381066_1382557_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MPNVSDFISKQLNKKKVVIGVSSIVIIALVGFYYLGGAKKAEGNYIAETVQRGTISSTISANGIVEPVNTVSLSFKNSEVINKIHVKLGDHVTTGQLLAEQDTANLQAQVTQASASLKSAVANLAIQKNSARPEEIAQAEADVSAAQASYELAKSNWERNQQLLQQEYISQAEFDQISYEYVNAEAKLKQAEESLKLLKAGNRPEEIAAATAQVESNSAQLQMAEKELAESKIYSPIDGIISAINGAEGQRATANNNNTSGGGFIDIISEALQVKAQVNESDIGKLKVGQQAEFTVNSFPEKTFTGRVSSISPQAYTESNVQLYDAIIQIDKNQTGLMAGMPANVNIIFERQENALTIPKGAVTYAANFQNKMRQSGDPNAKSIEGSANSGRTNSTRSGGDTHPNIDDTGGDTVKGDTLKQRDVVIVLNEAEKPVLRQVVLGLSDLSRYEVVEGLSMGEKVVVGALGQNTGGVSSQGSNPLMPGGGGMVRVGGAGR
>NC_021184.1|WP_006522652.1|1382675_1383407_+|ABC-transporter-ATP-binding-protein
MENIKKVYNMGETELHALKGISLTIQNGEMVAIMGSSGSGKSTLLNIMGCLDRPTGGTYYLDDENVSKLDKNQLAAIRNKRIGFVFQGFNLLGNVSVLANIQLPMIYAGAAKKEMVDRAKDALAWVGLSNYINHNPGQMSGGQQQRVAIARALVNNPSLILADEPTGALDSKTSIEIISMIQRLNIEKGITVVMVTHEKDIALYCRRLINVKDGQLIGDTPVLNQRNAAEDLSAFAEERGVLN
>NC_021184.1|WP_041284799.1|1383402_1384617_+|ABC-transporter-permease
MNFISNFVVAINGLKTNKLRSALTMLGIIIGVSAVIIMISVGQGASNKISSQIASMGSNLLMVSPSFGQGPVRGAGGSVNTLTLDDAEAIAELNMVTYVAPELSTNATIEYTSQTWTAQAVGTTPEMQMIKDWPASAGSFFTKDDVHGAAMVAVLGKTVADNLFPSGVNPVGSTIRINKLPFTVVGVLTAKGAAMMGQDQDDLIYIPVSAAQRRLMGVNYIRLINVQTQSSESMNYVQGSIEALLRERHRLVGAEDDFQVRNLTSVLETAESTTAVMTLLLASVAAVSLLVGGIGTMNIMLVSVTERTREIGLRMAVGATDSNIRNQFLMEALVLCLLGGLAGIVAGIAGSHIISKIFGWPTSVTVYSVLLSVGFSAVIGVFFGYYPANKAAKMDPMEALRFEK

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Click the colored protein region to show detailed information

Crispr_ID: NC_021184_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_9

1402575-1402683

Orphan

Consensus_repeat	Method
ATAGCTCAACGGTAGAGCATCCGGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_021184_9

>merge|NC_021184|9|1402575-1402683|CRISPRCasFinder
ATAGCTCAACGGTAGAGCATCCGGCTGTTAACCGGAGGGTTGCTGGTTCGAATCCAGCTCGGGGAGCCAATCCCTCTGGGCCCATAGCTCAACGGTAGAGCATCCGGCT

>NC_021184|9|9|1402575-1402683|CRISPRCasFinder
ATAGCTCAACGGTAGAGCATCCGGCT	GTTAACCGGAGGGTTGCTGGTTCGAATCCAGCTCGGGGAGCCAATCCCTCTGGGCCC
ATAGCTCAACGGTAGAGCATCCGGCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_041284802.1\|1399580_1401386_+\|DNA-primase	unknown	unknown	gnl\|CDD\|235551
NC_021184.1\|WP_006522671.1\|1403327_1404041_+\|DUF421-domain-containing-protein	unknown	unknown	gnl\|CDD\|225205
NC_021184.1\|WP_015617933.1\|1395114_1395435_+\|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	unknown	unknown	gnl\|CDD\|224987
NC_021184.1\|WP_006522664.1\|1395776_1395992_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NC_021184.1\|WP_006522675.1\|1405700_1406180_+\|stage-V-sporulation-protein-AC	unknown	unknown	gnl\|CDD\|131885
NC_021184.1\|WP_041284803.1\|1404541_1404748_+\|DUF1657-domain-containing-protein	unknown	unknown	gnl\|CDD\|377932
NC_021184.1\|WP_006522668.1\|1398446_1399526_+\|deoxyguanosinetriphosphate-triphosphohydrolase	unknown	unknown	gnl\|CDD\|234934
NC_021184.1\|WP_006522660.1\|1391590_1394248_+\|pyruvate,-phosphate-dikinase	unknown	unknown	gnl\|CDD\|236446
NC_021184.1\|WP_006522676.1\|1406185_1407199_+\|stage-V-sporulation-protein-AD	unknown	unknown	gnl\|CDD\|183504
NC_021184.1\|WP_006522680.1\|1409098_1409317_-\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006522672.1\|1404170_1404377_+\|DUF1657-domain-containing-protein	unknown	unknown	gnl\|CDD\|377932
NC_021184.1\|WP_006522679.1\|1408176_1408800_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NC_021184.1\|WP_006522667.1\|1397636_1398251_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NC_021184.1\|WP_006522678.1\|1407662_1408115_+\|Sporulation-lipoprotein-YhcN/YlaJ-like-protein	unknown	unknown	gnl\|CDD\|378211
NC_021184.1\|WP_006522665.1\|1395978_1396422_+\|hypothetical-protein	unknown	unknown	unknown
NC_021184.1\|WP_006522674.1\|1404807_1405668_+\|DUF421-domain-containing-protein	unknown	unknown	gnl\|CDD\|225205
NC_021184.1\|WP_157872741.1\|1396842_1397412_+\|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl\|CDD\|274058
NC_021184.1\|WP_006522659.1\|1390707_1391601_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|377080
NC_021184.1\|WP_006522677.1\|1407213_1407567_+\|stage-V-sporulation-protein-AE	unknown	unknown	gnl\|CDD\|131886
NC_021184.1\|WP_006522670.1\|1401382_1402501_+\|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl\|CDD\|236413

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_041284802.1\|1399580_1401386_+\|DNA-primase	gnl\|CDD\|235551	PRK05667, dnaG, DNA primase; Validated.	0
NC_021184.1\|WP_006522671.1\|1403327_1404041_+\|DUF421-domain-containing-protein	gnl\|CDD\|225205	COG2323, COG2323, Predicted membrane protein [Function unknown].	1.40223e-68
NC_021184.1\|WP_015617933.1\|1395114_1395435_+\|quaternary-ammonium-compound-efflux-SMR-transporter-SugE	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	1.72446e-33
NC_021184.1\|WP_006522664.1\|1395776_1395992_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	3.0084e-23
NC_021184.1\|WP_006522675.1\|1405700_1406180_+\|stage-V-sporulation-protein-AC	gnl\|CDD\|131885	TIGR02838, stage_V_sporulation_protein_AC, stage V sporulation protein AC. This model describes stage V sporulation protein AC, a paralog of stage V sporulation protein AE. Both are proteins found to present in a species if and only if that species is one of the Firmicutes capable of endospore formation, as of the time of the publication of the genome of Carboxydothermus hydrogenoformans. Mutants in spoVAC have a stage V sproulation defect. [Cellular processes, Sporulation and germination].	4.11697e-65
NC_021184.1\|WP_041284803.1\|1404541_1404748_+\|DUF1657-domain-containing-protein	gnl\|CDD\|377932	pfam07870, DUF1657, Protein of unknown function (DUF1657). This domain appears to be restricted to the Bacillales.	4.01711e-13
NC_021184.1\|WP_006522668.1\|1398446_1399526_+\|deoxyguanosinetriphosphate-triphosphohydrolase	gnl\|CDD\|234934	PRK01286, PRK01286, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NC_021184.1\|WP_006522660.1\|1391590_1394248_+\|pyruvate,-phosphate-dikinase	gnl\|CDD\|236446	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional.	0
NC_021184.1\|WP_006522676.1\|1406185_1407199_+\|stage-V-sporulation-protein-AD	gnl\|CDD\|183504	PRK12404, PRK12404, stage V sporulation protein AD; Provisional.	0
NC_021184.1\|WP_006522672.1\|1404170_1404377_+\|DUF1657-domain-containing-protein	gnl\|CDD\|377932	pfam07870, DUF1657, Protein of unknown function (DUF1657). This domain appears to be restricted to the Bacillales.	6.14995e-15
NC_021184.1\|WP_006522679.1\|1408176_1408800_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.43018e-45
NC_021184.1\|WP_006522667.1\|1397636_1398251_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	2.27637e-31
NC_021184.1\|WP_006522678.1\|1407662_1408115_+\|Sporulation-lipoprotein-YhcN/YlaJ-like-protein	gnl\|CDD\|378211	pfam09580, Spore_YhcN_YlaJ, Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ). This entry contains YhcN and YlaJ, which are predicted lipoproteins that have been detected as spore proteins but not vegetative proteins in Bacillus subtilis. Both appear to be expressed under control of the RNA polymerase sigma-G factor. The YlaJ-like members of this family have a low-complexity, strongly acidic, 40-residue C-terminal domain.	1.71991e-06
NC_021184.1\|WP_006522674.1\|1404807_1405668_+\|DUF421-domain-containing-protein	gnl\|CDD\|225205	COG2323, COG2323, Predicted membrane protein [Function unknown].	5.3692e-59
NC_021184.1\|WP_157872741.1\|1396842_1397412_+\|RNA-2',3'-cyclic-phosphodiesterase	gnl\|CDD\|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	2.72069e-46
NC_021184.1\|WP_006522659.1\|1390707_1391601_+\|kinase/pyrophosphorylase	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	7.68092e-148
NC_021184.1\|WP_006522677.1\|1407213_1407567_+\|stage-V-sporulation-protein-AE	gnl\|CDD\|131886	TIGR02839, stage_V_sporulation_protein_AE, stage V sporulation protein AE. This model describes stage V sporulation protein AE, a paralog of stage V sporulation protein AC. Both are proteins found to present in a species if and only if that species is one of the Firmicutes capable of endospore formation, as of the time of the publication of the genome of Carboxydothermus hydrogenoformans. Mutants in spoVAE have a stage V sproulation defect. [Cellular processes, Sporulation and germination].	4.13287e-48
NC_021184.1\|WP_006522670.1\|1401382_1402501_+\|RNA-polymerase-sigma-factor-RpoD	gnl\|CDD\|236413	PRK09210, PRK09210, RNA polymerase sigma factor RpoD; Validated.	0

>NC_021184.1|WP_006522670.1|1401382_1402501_+|RNA-polymerase-sigma-factor-RpoD
MSRDDSKEKRIVKNVKELIEKGKKRGAVTYHEVMDSLQGIELTPEQIDDVYEKLSAMGIEVVPDVQDIETVNASPLEEEDNDSSDDVEVDLTVPEGVGIDDPVRMYLKEIGRVPLLTPEREVELAKRMEEGDEEAKRLLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYRKGYKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRVSRQLLQELGREPLPEEIAKEMGISEEKVREILKIAQEPVSLETPIGEEEDSHLGDFIEDHDARAPAEEASFTLLREQLDDVLTTLTDREQKVLRLRFGLDDGRARTLEEVGQKFGVTRERIRQIEAKTLRKLRHPSRSKKLKDYLD
>NC_021184.1|WP_041284802.1|1399580_1401386_+|DNA-primase
MGGFIPEEIVENIRLRADIVQIISDYVTLQKKGRNYMGHCPFHQESDPSFTVTPDKQIFYCFGCHAGGNVFKFIMLQHNLSFPEAVKMLGEKVGIAVPDGYSPQVRERLRREEKAWKINNLAKDFFQSILLQHSEAAAAREYIHGRGINANIIKDFGLGYAPASWDTLMKFMQSKGIGVSDLLKVGLVVSGDRGVYDRFRSRLMFPIADARGRVVGFGGRVLGDGLPKYLNTAETDFFSKGKILYGLDRARQAIREMRYVVITEGYMDTIAAHQYGMANTVASLGTSLTKEHGRLLMNYTREVIIAYDADAAGVAAAVRGLDILQELGCRVRVLSLPEGKDPDEFLRARGLDQWKRQVENATPLVEFKIQRALAKYNNGPLARDAVLEEVLPALAAMPGELEKNEAIRLVAARLFTSYHVVAEQLQKFSNSNRKKTTKPDKIAKIKHNINNKRIANDFGKKAEYGLIRFILEDNKVIDLVAGALPGNFFQDDFCREVYAKIIDAYNRSYAHTSSVVLDHLDEEYQKKLSAMLIEPVPGENPELIVKGYINAIKKRQLLEHRRQLQDALAGAEKAGDYNEIIRILQEIGFTDQTLKGGEMLQ
>NC_021184.1|WP_006522668.1|1398446_1399526_+|deoxyguanosinetriphosphate-triphosphohydrolase
MEIRQHTEAMEDNYLSPFGARSHRSVGRRFSEEPCRIRTAFQRDRDRIIHSKAFRRLKHKTQVFIIPEGDHYRTRLTHTLEVAQIARTVARALRLNEDLTEAIALGHDLGHTPFGHAGENALNEIMPGGFKHNRQSLRVVEELEEGTGLNLTWEVCDGILHHTGPVRPSTLEGQVVKIADRVAYINHDIDDAIRGGILLVEDLPTFCLDILGREHRTRINTMVTDLIISSRDKPLISMSSTVHEATDKLRQFLFDHVYIDSEAKGEEGKARHVLQYLFTHWVKNPQCLPEEHRARSQVVGVERAVCDYIAGMTDRYAIAQFKQLFIPRSFAIPKITSLCTAYGKQKNVELGRIIYSDSE
>NC_021184.1|WP_006522667.1|1397636_1398251_+|flavodoxin-family-protein
MLIIAINGSPNAEGNTALMLRTALDEITTAGGEGHFMQVSDLLAKAKVPYCVVCSNPCEGRCFRGTALEAAYDLLRRCDGIIMGSPVYFCTVSAQIKAFWDKARYLRKDKALLNVVGGALSVGAGRFGGQESTLRALQDMMLCQGMTVVGDGFNDNDSGHLGACAQRMAKDDQDGLKRTRILARRVLEVAQATASLRVHRTQGK
>NC_021184.1|WP_157872741.1|1396842_1397412_+|RNA-2',3'-cyclic-phosphodiesterase
MLQSRLFWAINLPVDLKRKLGNLQSCLKTAPVNIKWVEQHNLHLTVKFLGDVDDSRVSEITRAVNEAAGGLGSFKLELSGIGFFPGPRRPRVIWVGVQGEVHKLRLLHRRVEECMAGLGWDSNSQGFAPHLTLGRLRTPQGGEMLAGKADKLASQLGVIGSLTVSGIDLMKSRLTRNGPVYQVLVSVKI
>NC_021184.1|WP_006522665.1|1395978_1396422_+|hypothetical-protein
MKKSNLYVGLIYLFIGIVCLVIALNFESRLESLLFGFTGAGICSGAVILWKYYYWTRAENKDRYQEKIENENIELHDERKTILRDKSGRYAYIIGLIVISMSIVIFSIMGSLDIIKNSKFITLYLAGFLVFQYVIGILMYNHLNKKY
>NC_021184.1|WP_006522664.1|1395776_1395992_+|helix-turn-helix-transcriptional-regulator
MENKVEELRKRIGLNQEDLAKALKVSRQTISSIETGKYNPSLELAFAISDYFKKSIEEIFVYEGRGENEKK
>NC_021184.1|WP_015617933.1|1395114_1395435_+|quaternary-ammonium-compound-efflux-SMR-transporter-SugE
MKWLLLVIAGLLEMCWAVGLKYSQGFTKLMPSVFTIVGMIASFYFLSLALKSLPLGTAYAIWTGIGTVGTVILGIILFKEPVDMTRLIFIGFIVIGIIGLKLVSAH
>NC_021184.1|WP_006522660.1|1391590_1394248_+|pyruvate,-phosphate-dikinase
MVVSKWVYTFEEGRADMKDLLGGKGANLAEMTNIGLPVPPGIVITTDACNQFYVENRQFPPGMEEQVRDKIKTLEEKTGKSFGDPDNPLLVSVRSGAPISMPGMMDTVLNLGLNDETVKGLARAAGDERFAMDCYRRFLNMFGDVVLGIEHEKFERILETQKDMANVQFDNQLTAEQWQVVVEEYKKLIERETGSPFPQEPMDQLFKSIYAVFNSWNNDRAIVYRKVNKIPDSLGTAVNVQVMVFGNLGNDCGTGVAFTRDPSTGVNELYGEYLINAQGEDVVAGIRTPQPIATLKDEMPGVYKQFAETCTLLEKHYRNMQDIEFTIERGKLWMLQTRNGKRTAQAAIKVAVDMVNEGLITKEEAIMRVEPAHLDHLLHRRIDPNASLQVIAKGLPASPGAAGGQVVFDADEAEKLGLEGQKVILVRTETTPDDIHGIVQAQGILTSRGGMTSHAAVVARGMGKPCVCGCEAMRIDYTNEEFLVSGLTVKKGDIVSIDGATGQVMLGEVPMIDPELSDEFQQLLTWADEIRALGVRANADTPGDAAKAREFGAEGIGLTRTEHMFMAQDRLPIVQQMILADTDEERDKALAKLLPVQEEDFYGILKAMESLPVTIRLLDPPLHEFLPNAEELMVEITTLRLTGGDAGEIKQKEELLKKVRALSEFNPMLGHRGCRLGITFPAVYAMQARAIFQAVVRLVQEGYKVIPEVEIPLVIDVNELSFLRNTVEQVAADVMKETGVEFEYTVGTMIEVPRAALLADEVAGAADFFSFGTNDLTQTTLGFSRDDAEGKFMQDYIEKKILKENPFVVLDRNGVGKLMQTAVQLGRSVKPDLLIGICGEHGGEPSSVEFCHLIGLNYVSCSPFRVPIARLAAAQAAVINKDQSK
>NC_021184.1|WP_006522659.1|1390707_1391601_+|kinase/pyrophosphorylase
MSPDCLLNWVKVVTKEAVSISAVNKQPRPVIYIISDSIGETAELVARAAASQFNGREVEIRRVPYVNEASEIPEIVEEAGQFNSLIAYTLVLPELRETLVAEAKKHQVLTVDIMSPMLDALTKLEGSQPKLEPGLVRKMDREYFRKVEAIEFAVKYDDGKDPRGILRADLVVIGVSRASKTPLCMYLAHRRIKAANVPLVPEVAPPEEIFSLARHKVIGLKISPNQLNEIRRERLKSLGLTSNADYASMERILKELEYAEKTMKKIGCPIIDVTNKAIEETASRVLEIYYRGERHGS
>NC_021184.1|WP_006522671.1|1403327_1404041_+|DUF421-domain-containing-protein
MLINPYIEIPLRALFAYLFLLLFTRINGREQISQLTYFEYVVGITIGSIAGTLTTTPEDPFGPGLLGMAVWTILPILTGLLVLKSVPARKIIEGEPIVVIQNGKIDEEALARQRTNLDDLMLMLRQKDIFNIGDVENAIFERNGELTVQRKSQLNPVTPADLNISTLYQGLPTTLVQDGVVIENRLKEISLSKDWLLKKLQTEHGVNEISQVSIAQLDTSGNLYVDLKNANPENKPH
>NC_021184.1|WP_006522672.1|1404170_1404377_+|DUF1657-domain-containing-protein
MTVATQVKQTLAGLKSAQASLETFAMQTQNQQAKDLYTNAAQQTQTIVNSLEPRINEIEQQEPQYKGF
>NC_021184.1|WP_041284803.1|1404541_1404748_+|DUF1657-domain-containing-protein
MTVSAQVKQTIASLKGTRATLESFADIEQNDQAEQILYKNITRLEGVIKDMENRLSVLEFEEPQYKGF
>NC_021184.1|WP_006522674.1|1404807_1405668_+|DUF421-domain-containing-protein
MVEWLEVLLRSVGLFVITLFLARLIGKRQTSRLTFFDLITAIVIGGIATVISLNLVPNLLHGLVALVVWTLLPALIYLLSIKYKTVRDIVQGKETVLINHGKVLEDKLMEARYTPEDLLSQLRKKNAFKVADVEFAVLEPTGEVSVLLKKDQQPVTPKTAGLNVGLESVPQTVIMDGIIMDEPLTAMGLNRNWLHTELEKAGVAPENVFIGQVDSTGQLYLDLFDDAIQVPKPKTKELAWATIKKCQADCELYALGAKQPEAREMYGKSAAVLADVVNELEPLLKR
>NC_021184.1|WP_006522675.1|1405700_1406180_+|stage-V-sporulation-protein-AC
MSNKQKKKLTAVQQEYQSFAKAREPGRPVAKNIIRAFIAGGIICIIAQGISEFFLWNFDFTEKTVGNPTVAVMILISVILTSFGVYDHIAQWAGAGTAVPVTGFANSIASAAIEHRSEGFVLGVGGNMFKLAGSVIVFGVFAAFVIALIKTTLAMLGGG
>NC_021184.1|WP_006522676.1|1406185_1407199_+|stage-V-sporulation-protein-AD
MLQGHQTWVFNNRPTIISAATVGGPFEAEGPLANDFDLLHGDLWLGQDSYEKAQKKMLEEACEKAIQKGGLQKQDIQFFLAGDLLNQIISSSFAARTMAMPFLGLYGACSSSMESLALGALIVNSKAGNYVLCGTVSHNGAVEKQFRYPTEYGAQKPPTAQWTATAAGVALLAAEGEGPKVTCATIGRIVDMGISDPYNMGGAMAPAAVDTITAHFRDLRINPREYDIIATGDLGRVGHEIASDLLKKHNIDIPTEIFTDCGLLIYGPNQQSEVLAGGSGCGCSAAVTYGHLLNRMKKGELRKILIVATGALLSPLSYQQKESIPCIAHAVSIVSSQ
>NC_021184.1|WP_006522677.1|1407213_1407567_+|stage-V-sporulation-protein-AE
METYFWAFVVGGLICVIGQLLMDVGKLTPAHTISSMVVAGAVLAGLGLYEPLIDFAGAGATIPITSFGNSLVHGAMAEAEQTGLVGIITGIFEVTSAGISAAIIFGFMAALLVRPKG
>NC_021184.1|WP_006522678.1|1407662_1408115_+|Sporulation-lipoprotein-YhcN/YlaJ-like-protein
MNKLVKAVILSLIICIIGGCAVNMPQRKPEPQTGQVEGQAHINTELTKQVQEVALTVQGVEESMALVIDNQIAVAVKVTGFDRLRLKSIRQELNSQIKSMAPEYDVHVSTDKKLFAQLQKLAEQIKRAPQDNLPAQIKDDYNVIIEDMNG
>NC_021184.1|WP_006522679.1|1408176_1408800_-|flavodoxin-family-protein
MYIIAINGSHRKGKNTAILLNALLAEAADLGATTELLELTDYNIKLCRSCNKCMGRNQCSITDDDMPAIGEKLLAADGIVLGSPAYWANVTTLMKNFMDRTRYLHVTRNMLAGKVGAAVTNAGLRNGGQEAALRIMTFFMSAQGLTLVDARNQNKPIMSDGVAGSLLADVKEGKAIWRKSVEEDEAAMLAARQLGRNMVELIRSLSK
>NC_021184.1|WP_006522680.1|1409098_1409317_-|hypothetical-protein
MVLLMILAFLGIIGLEVPGLVRKKMWRELTAFAALLVIGMALSIPQTLGMTIPNPNTYIEILFKPMVEWLKK

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Click the colored protein region to show detailed information

Crispr_ID: NC_021184_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_021184_10

4234677-4241878

orTypeI

I-C

Consensus_repeat	Method
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	PILER-CR
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CRISPRCasFinder
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CRT

108 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NC_021184_10

>merge|NC_021184|10|4234677-4241878|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGACCTGAGGGCGCAGTCTTGGAGAACTTTAAGCGGAAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATAACCGAACACGTCCAGGGGTTCCTCGCAGAAGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTAATATTATCCTTGCCGACATCAACCCCGATACCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAAGTTACGTACCCACGAGGTGATGCGCTTGTGTGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCCGAGGATGCGGCCACAAATCTATTGCAGGAAATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGAATGTGCAGCGGCTTTTGTCAGTTCATAGCTATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAAATTATAAGCGCCATTGGCGTCGGTGACATCAAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACACATTTACTGATATGGTACGTGCAAAGGCATCAGAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTACCAGTACCTTTTAGATCGAGCCACCTGTGGGGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCGGTATCCTCTCCGCGCAGGCTGCGGGGCATTGAGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAGCCATGTAAGACATCTCTCCTTTTAATTAATTAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCACCGGCTCCGGGCATCGTTGATCCGTTCAATGCAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTTCGCCTTTAAAAACATGTTCGTTGAACAGCTGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGATCGATATCAATTAGGAAAGGGGGCCGACGATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGACAGCACAACGCCGGGATAAATCTTTTTTATAGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAATACAAACTAGAATGCTTAGTAATATTTCTAGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCGAACCAGGCAACAACTCGCGCTTCAATCGCGGAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTTCATCAATCGCTCTCATGCTACTGCCAATCTGTTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCGACAGCTTATATGGACGGCATGGCGGTGGCAGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGGTAAATTTCTCTTGTGTATTATGATTTATGTTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCCTAGTATTGTACGACCAACAAAGTCACAAGTTGAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATTGTGGATAATAGTATGGCCATGAGGAATAGGCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAAGTGTTTGGCTTATGCTTATTGGTTAAGTCAAACATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTGAGGACATGCGCGAAGATGTAAAGGAAATCAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATTGGATGCAATCAATCAACTAAAAGCCAGTGGGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAACGGTGAGGGGGAAAGTAAAAGATGAAAATAGATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAACCTCGGACGCACGATTAAAGCTTTGTTTAAATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTTAGCCATTTGCAGCAGATTGTCTGCGGGTATTGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAATGCGTTTGTGATGCAGTGGGGGCTGAGATTAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTATCGCTTTTCGGAACCCAAGCCCAAGCGAGATTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACACAAATCATAGCCGAGCTGCAGCGGCGGGAGCAGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAGCCCAATGCGCCCGCAATCGGAGCAACGTATTTGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATTTATGGAGATTATGTGTCGACTGACGGAATGGGTTTCAATCCACGCCCCCGCGCGGGGGGCGATGGAAATTATCGGCGGTGAAGATGAAATTTTATCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGACATAGATTGCTGGCTGCAGGGTTTATAGTGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTTATTTTGTTGAATTGGTTTTTGATATGGCAGAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCATCGGCGGGCTCTTCATGGATATGGGGACTGGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCCACTGGCTGTGTATATGCTGGAAGGGAAAAAGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGTCAACGGTTTCGCCGGGTTTGAATTCCCTGTCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCCCACCCATGGCCGTTCCGGATCTGGGTTGATGACGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTCAGCCGGCCAAATTGCTGACCTGTTAAATCAATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGAAATGGAGGGAAATACTGTGATTATCGAGAGTAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTTCAATAGCTTGCTTATGCAGCCCACATAATTCGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATTGGGCGTAAAACGCCAAGTGTTTGCATATCTGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGTTTCACCTCCTCCTGTTCTTTTTCATCCTGACAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTGGGCACTATACTTGTATCTCATCGAGCAGGGCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACACTGCAAGCGCCGGGTGGCGGGCGGAAAGGAAGGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCTTACCCAGACCCGGATAAGAAGCCTATTTTTGAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCGTTGGCGTGATCGTTCCCGTATTCGCTAAATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTGCCTGTCCAGCAAAAATATTTTGCTGCAAAAATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGACATAGATTGCTGGCTGCAGGGTTTATAGTGCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATGGCATGAACATGGACGAGTTCTTTTCTGAGCTCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCTGCCCTATTGGTCGGTCAGTATGTGCATAGTTGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCCAACACGGATCGGGGCCTTGTTCATGGAGATGGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTATCTGTTTCTTTTTTTGCCTTTTGACCCATCAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCTGGCTGTTTATGGCCGCTTCAAGGCGGATAAGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCCGTATGCAAAGGGTTCACAGCGGAAAGTTATCTCGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATCAATAGCGGACGGTAAAGCGATGGTGCAGGTTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGGCGAAGTCAGGCAAGACTACGCTGGCATTGCAGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGAGTCGGAGCCAGTACATCGGCTTTTTAGAATGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCATAAATAAAGTCTTTTGTAAACTGATCACCTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCTACAGGAAATACGGGTGTCTAGCTTGATACACGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCGTTGTACCACCCACAGGATCACCTCCAGGTTCATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAACATAGATTCATCCTCCTTTTGTTTTGTTATATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTCTGACCATAGTTCAAACTGTGCTGCTGTGCCCGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGACCGGGTCCGTATTCTGATCGGCCACAACAAAGGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATGGCGCTTCAGGAGATGTTAGACGATTTACTATCTTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACACTGTACCGCCTCACCTTTAAACCCACCCGGTTTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCGGCGATGGGCTTCAGACAATGCCAGATGGGCCAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACACCTCAATACTTTAATCCAGATGCGGACAATTACGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTCTACCTGAGCGCGATCAGCGGTCCTGGTGAAGGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTATGCTTTAGATTGAGGTGTTTTAAATGAGTAAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGTGACACCTGGGGAATGTTCTTCCCTCCTACTATGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGATATTGGAACCAGCGAGTCAAGCGGGGTGTGTATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTAGGCAAAGAGTATCTGTCCGAGTTTATTTTAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCGACTATATGTACAAGAAAGGTATGGGATTACAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCGGAATAGCTCTAACGCCGGGAGATTACTTTTACGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTGCCGCAGGTACCGCCAAGTCTGAACGTATGGAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCAACGCGCAACTCTTTCATTTGTTGTAGATTGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTATAGAGGAAATACAGGTGTCAGAACAACTAAGTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTATCCGACATTGGAACTAGCCGAGTATACCAGTAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCATAAAAGAATTCGCCGAAGATACTGGTATAGATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATCAACTAACTAATTAAGGAGTGATCTTTTTGATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACACGTTAACTATTTTATTATTTTCATTTAATGTAATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCCGTATCTGTGTTGGCCTAGTTTTCTTCCAAAGAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGCCATTGAGGCCCGGGTGATTGCATGGCTTGCCGGAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGTTAAAAGCCAAACTGTACGACCACATGGTAAAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAATAGTTAGGCTCCTTTTCAATTAATTTTAAGGAGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTAAAAATTCTTTTCTATTATCATTTTTATTATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTGGCTTCTTTTTGGTGCTCTTTATCTAACATCCGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGGAATTTCATTATGCACACCACCTTCAATTTAATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCCTTTGGCCGTTTTAACCAGCAAAAAGGCAAAAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATTATCCACAAAGGCACAGCAACCGATTGCTTTAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTATACTCCAACAACTTTTCATATTCTACTTTAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTTTCCAATTAGAATCTTGAAAACTAGCAGACATAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCTTCATCTGCTTTTTTCTTATTTTCAATCCAAATTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTATGTGATATAATGGTTTCGCTGAGTATGTGAGGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAGGTTCCGGGCCTGGAGGTACGCCCGGCGATGCCGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACCTTTATTTTTATTTGTTTTTGTATTTATTTATTTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAAGTGAAGATTTTGATGGGTTAATTTTAGCATTAGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGAGTACTGCCGGCAGGATGTTGTCACAGAAATGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAGCCCATGGGATGGCCAACACCTGGGACGAAATTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACTGGAAAAGATGCTAACAGCATTTACACCACTATTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACGTGTCAACCATGACCAATCTTTTGCATTTTCTTTGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAAGCACTAATGTATTTTTGCAAGGGCTGGCCCACGTTTCAATCCACGCCCCCGCGCGGGGGGCGACAATATGAAAATTGGTGGTAGAGCTTTATCAAACGGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATATTGGTGCTAGAGAATGTACTAGATATATGTATGTTTCAATCCACGCCCCCGCGCGGGGGGCGACATTACTGGATAATATTATTTTAAGTATGGTAAAAAGTTTCAATCCACGCCCCCGCGCGGGGGGCGAC

>NC_021184|10|6|4234677-4241878|PILER-CR
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTGAGGGCGCAGTCTTGGAGAACTTTAAGCGGAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATAACCGAACACGTCCAGGGGTTCCTCGCAGAAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTAATATTATCCTTGCCGACATCAACCCCGATACC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTTACGTACCCACGAGGTGATGCGCTTGTGTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCGAGGATGCGGCCACAAATCTATTGCAGGAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAATGTGCAGCGGCTTTTGTCAGTTCATAGCTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAATTATAAGCGCCATTGGCGTCGGTGACATCAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACATTTACTGATATGGTACGTGCAAAGGCATCAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TACCAGTACCTTTTAGATCGAGCCACCTGTGGGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGGTATCCTCTCCGCGCAGGCTGCGGGGCATTGAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCATGTAAGACATCTCTCCTTTTAATTAATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CACCGGCTCCGGGCATCGTTGATCCGTTCAATGCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTTCGCCTTTAAAAACATGTTCGTTGAACAGCTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGATCGATATCAATTAGGAAAGGGGGCCGACGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GACAGCACAACGCCGGGATAAATCTTTTTTATAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATACAAACTAGAATGCTTAGTAATATTTCTAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGAACCAGGCAACAACTCGCGCTTCAATCGCGGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCATCAATCGCTCTCATGCTACTGCCAATCTGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGACAGCTTATATGGACGGCATGGCGGTGGCAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGGTAAATTTCTCTTGTGTATTATGATTTATGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCTAGTATTGTACGACCAACAAAGTCACAAGTTGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGTGGATAATAGTATGGCCATGAGGAATAGGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTGTTTGGCTTATGCTTATTGGTTAAGTCAAACAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTGAGGACATGCGCGAAGATGTAAAGGAAATCAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGGATGCAATCAATCAACTAAAAGCCAGTGGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACGGTGAGGGGGAAAGTAAAAGATGAAAATAGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACCTCGGACGCACGATTAAAGCTTTGTTTAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTAGCCATTTGCAGCAGATTGTCTGCGGGTATTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATGCGTTTGTGATGCAGTGGGGGCTGAGATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATCGCTTTTCGGAACCCAAGCCCAAGCGAGATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACAAATCATAGCCGAGCTGCAGCGGCGGGAGCAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCCAATGCGCCCGCAATCGGAGCAACGTATTTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTTATGGAGATTATGTGTCGACTGACGGAATGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAT	GGAAATTATCGGCGGTGAAGATGAAATTTTATC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGACATAGATTGCTGGCTGCAGGGTTTATAGTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTTATTTTGTTGAATTGGTTTTTGATATGGCAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCATCGGCGGGCTCTTCATGGATATGGGGACTGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCACTGGCTGTGTATATGCTGGAAGGGAAAAAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTCAACGGTTTCGCCGGGTTTGAATTCCCTGTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCCACCCATGGCCGTTCCGGATCTGGGTTGATGAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTCAGCCGGCCAAATTGCTGACCTGTTAAATCAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAAATGGAGGGAAATACTGTGATTATCGAGAGTAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCAATAGCTTGCTTATGCAGCCCACATAATTCGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGGGCGTAAAACGCCAAGTGTTTGCATATCTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTTTCACCTCCTCCTGTTCTTTTTCATCCTGACA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGGCACTATACTTGTATCTCATCGAGCAGGGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACTGCAAGCGCCGGGTGGCGGGCGGAAAGGAAGGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTACCCAGACCCGGATAAGAAGCCTATTTTTGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGTTGGCGTGATCGTTCCCGTATTCGCTAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTGCCTGTCCAGCAAAAATATTTTGCTGCAAAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGACATAGATTGCTGGCTGCAGGGTTTATAGTGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATGGCATGAACATGGACGAGTTCTTTTCTGAGCTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTGCCCTATTGGTCGGTCAGTATGTGCATAGTTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCAACACGGATCGGGGCCTTGTTCATGGAGATGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTATCTGTTTCTTTTTTTGCCTTTTGACCCATCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCTGGCTGTTTATGGCCGCTTCAAGGCGGATAAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCGTATGCAAAGGGTTCACAGCGGAAAGTTATCTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATCAATAGCGGACGGTAAAGCGATGGTGCAGGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGGCGAAGTCAGGCAAGACTACGCTGGCATTGCAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAGTCGGAGCCAGTACATCGGCTTTTTAGAATGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCATAAATAAAGTCTTTTGTAAACTGATCACCT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTACAGGAAATACGGGTGTCTAGCTTGATACAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGTTGTACCACCCACAGGATCACCTCCAGGTTCAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACATAGATTCATCCTCCTTTTGTTTTGTTATAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TCTGACCATAGTTCAAACTGTGCTGCTGTGCCCGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GACCGGGTCCGTATTCTGATCGGCCACAACAAAGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATGGCGCTTCAGGAGATGTTAGACGATTTACTATCTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACTGTACCGCCTCACCTTTAAACCCACCCGGTTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGGCGATGGGCTTCAGACAATGCCAGATGGGCCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACCTCAATACTTTAATCCAGATGCGGACAATTAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTCTACCTGAGCGCGATCAGCGGTCCTGGTGAAGGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATGCTTTAGATTGAGGTGTTTTAAATGAGTAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTGACACCTGGGGAATGTTCTTCCCTCCTACTATG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GATATTGGAACCAGCGAGTCAAGCGGGGTGTGTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTAGGCAAAGAGTATCTGTCCGAGTTTATTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGACTATATGTACAAGAAAGGTATGGGATTACAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGGAATAGCTCTAACGCCGGGAGATTACTTTTACG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTGCCGCAGGTACCGCCAAGTCTGAACGTATGGAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCAACGCGCAACTCTTTCATTTGTTGTAGATTGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTATAGAGGAAATACAGGTGTCAGAACAACTAAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATCCGACATTGGAACTAGCCGAGTATACCAGTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CATAAAAGAATTCGCCGAAGATACTGGTATAGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATCAACTAACTAATTAAGGAGTGATCTTTTTGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACGTTAACTATTTTATTATTTTCATTTAATGTAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCGTATCTGTGTTGGCCTAGTTTTCTTCCAAAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCATTGAGGCCCGGGTGATTGCATGGCTTGCCGGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTTAAAAGCCAAACTGTACGACCACATGGTAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATAGTTAGGCTCCTTTTCAATTAATTTTAAGGAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTAAAAATTCTTTTCTATTATCATTTTTATTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGCTTCTTTTTGGTGCTCTTTATCTAACATCCG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGAATTTCATTATGCACACCACCTTCAATTTAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCTTTGGCCGTTTTAACCAGCAAAAAGGCAAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTATCCACAAAGGCACAGCAACCGATTGCTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTATACTCCAACAACTTTTCATATTCTACTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCCAATTAGAATCTTGAAAACTAGCAGACATA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTCATCTGCTTTTTTCTTATTTTCAATCCAAATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATGTGATATAATGGTTTCGCTGAGTATGTGAGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGGTTCCGGGCCTGGAGGTACGCCCGGCGATGCCG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTTATTTTTATTTGTTTTTGTATTTATTTATTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTGAAGATTTTGATGGGTTAATTTTAGCATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAGTACTGCCGGCAGGATGTTGTCACAGAAATG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCCATGGGATGGCCAACACCTGGGACGAAATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGAAAAGATGCTAACAGCATTTACACCACTATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTGTCAACCATGACCAATCTTTTGCATTTTCTTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGCACTAATGTATTTTTGCAAGGGCTGGCCCAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATATGAAAATTGGTGGTAGAGCTTTATCAAACG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATATTGGTGCTAGAGAATGTACTAGATATATGTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTACTGGATAATATTATTTTAAGTATGGTAAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC

>NC_021184|10|10|4234677-4241878|CRISPRCasFinder
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTGAGGGCGCAGTCTTGGAGAACTTTAAGCGGAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATAACCGAACACGTCCAGGGGTTCCTCGCAGAAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTAATATTATCCTTGCCGACATCAACCCCGATACC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTTACGTACCCACGAGGTGATGCGCTTGTGTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCGAGGATGCGGCCACAAATCTATTGCAGGAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAATGTGCAGCGGCTTTTGTCAGTTCATAGCTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAATTATAAGCGCCATTGGCGTCGGTGACATCAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACATTTACTGATATGGTACGTGCAAAGGCATCAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TACCAGTACCTTTTAGATCGAGCCACCTGTGGGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGGTATCCTCTCCGCGCAGGCTGCGGGGCATTGAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCATGTAAGACATCTCTCCTTTTAATTAATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CACCGGCTCCGGGCATCGTTGATCCGTTCAATGCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTTCGCCTTTAAAAACATGTTCGTTGAACAGCTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGATCGATATCAATTAGGAAAGGGGGCCGACGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GACAGCACAACGCCGGGATAAATCTTTTTTATAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATACAAACTAGAATGCTTAGTAATATTTCTAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGAACCAGGCAACAACTCGCGCTTCAATCGCGGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCATCAATCGCTCTCATGCTACTGCCAATCTGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGACAGCTTATATGGACGGCATGGCGGTGGCAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGGTAAATTTCTCTTGTGTATTATGATTTATGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCTAGTATTGTACGACCAACAAAGTCACAAGTTGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGTGGATAATAGTATGGCCATGAGGAATAGGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTGTTTGGCTTATGCTTATTGGTTAAGTCAAACAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTGAGGACATGCGCGAAGATGTAAAGGAAATCAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGGATGCAATCAATCAACTAAAAGCCAGTGGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACGGTGAGGGGGAAAGTAAAAGATGAAAATAGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACCTCGGACGCACGATTAAAGCTTTGTTTAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTAGCCATTTGCAGCAGATTGTCTGCGGGTATTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATGCGTTTGTGATGCAGTGGGGGCTGAGATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATCGCTTTTCGGAACCCAAGCCCAAGCGAGATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACAAATCATAGCCGAGCTGCAGCGGCGGGAGCAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCCAATGCGCCCGCAATCGGAGCAACGTATTTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTTATGGAGATTATGTGTCGACTGACGGAATGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAT	GGAAATTATCGGCGGTGAAGATGAAATTTTATC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGACATAGATTGCTGGCTGCAGGGTTTATAGTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTTATTTTGTTGAATTGGTTTTTGATATGGCAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCATCGGCGGGCTCTTCATGGATATGGGGACTGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCACTGGCTGTGTATATGCTGGAAGGGAAAAAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTCAACGGTTTCGCCGGGTTTGAATTCCCTGTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCCACCCATGGCCGTTCCGGATCTGGGTTGATGAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTCAGCCGGCCAAATTGCTGACCTGTTAAATCAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAAATGGAGGGAAATACTGTGATTATCGAGAGTAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCAATAGCTTGCTTATGCAGCCCACATAATTCGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGGGCGTAAAACGCCAAGTGTTTGCATATCTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTTTCACCTCCTCCTGTTCTTTTTCATCCTGACA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGGCACTATACTTGTATCTCATCGAGCAGGGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACTGCAAGCGCCGGGTGGCGGGCGGAAAGGAAGGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTACCCAGACCCGGATAAGAAGCCTATTTTTGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGTTGGCGTGATCGTTCCCGTATTCGCTAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTGCCTGTCCAGCAAAAATATTTTGCTGCAAAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGACATAGATTGCTGGCTGCAGGGTTTATAGTGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATGGCATGAACATGGACGAGTTCTTTTCTGAGCTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTGCCCTATTGGTCGGTCAGTATGTGCATAGTTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCAACACGGATCGGGGCCTTGTTCATGGAGATGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTATCTGTTTCTTTTTTTGCCTTTTGACCCATCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCTGGCTGTTTATGGCCGCTTCAAGGCGGATAAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCGTATGCAAAGGGTTCACAGCGGAAAGTTATCTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATCAATAGCGGACGGTAAAGCGATGGTGCAGGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGGCGAAGTCAGGCAAGACTACGCTGGCATTGCAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAGTCGGAGCCAGTACATCGGCTTTTTAGAATGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCATAAATAAAGTCTTTTGTAAACTGATCACCT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTACAGGAAATACGGGTGTCTAGCTTGATACAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGTTGTACCACCCACAGGATCACCTCCAGGTTCAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACATAGATTCATCCTCCTTTTGTTTTGTTATAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TCTGACCATAGTTCAAACTGTGCTGCTGTGCCCGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GACCGGGTCCGTATTCTGATCGGCCACAACAAAGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATGGCGCTTCAGGAGATGTTAGACGATTTACTATCTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACTGTACCGCCTCACCTTTAAACCCACCCGGTTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGGCGATGGGCTTCAGACAATGCCAGATGGGCCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACCTCAATACTTTAATCCAGATGCGGACAATTAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTCTACCTGAGCGCGATCAGCGGTCCTGGTGAAGGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATGCTTTAGATTGAGGTGTTTTAAATGAGTAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTGACACCTGGGGAATGTTCTTCCCTCCTACTATG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GATATTGGAACCAGCGAGTCAAGCGGGGTGTGTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTAGGCAAAGAGTATCTGTCCGAGTTTATTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGACTATATGTACAAGAAAGGTATGGGATTACAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGGAATAGCTCTAACGCCGGGAGATTACTTTTACG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTGCCGCAGGTACCGCCAAGTCTGAACGTATGGAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCAACGCGCAACTCTTTCATTTGTTGTAGATTGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTATAGAGGAAATACAGGTGTCAGAACAACTAAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATCCGACATTGGAACTAGCCGAGTATACCAGTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CATAAAAGAATTCGCCGAAGATACTGGTATAGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATCAACTAACTAATTAAGGAGTGATCTTTTTGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACGTTAACTATTTTATTATTTTCATTTAATGTAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCGTATCTGTGTTGGCCTAGTTTTCTTCCAAAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCATTGAGGCCCGGGTGATTGCATGGCTTGCCGGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTTAAAAGCCAAACTGTACGACCACATGGTAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATAGTTAGGCTCCTTTTCAATTAATTTTAAGGAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTAAAAATTCTTTTCTATTATCATTTTTATTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGCTTCTTTTTGGTGCTCTTTATCTAACATCCG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGAATTTCATTATGCACACCACCTTCAATTTAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCTTTGGCCGTTTTAACCAGCAAAAAGGCAAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTATCCACAAAGGCACAGCAACCGATTGCTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTATACTCCAACAACTTTTCATATTCTACTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCCAATTAGAATCTTGAAAACTAGCAGACATA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTCATCTGCTTTTTTCTTATTTTCAATCCAAATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATGTGATATAATGGTTTCGCTGAGTATGTGAGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGGTTCCGGGCCTGGAGGTACGCCCGGCGATGCCG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTTATTTTTATTTGTTTTTGTATTTATTTATTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTGAAGATTTTGATGGGTTAATTTTAGCATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAGTACTGCCGGCAGGATGTTGTCACAGAAATG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCCATGGGATGGCCAACACCTGGGACGAAATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGAAAAGATGCTAACAGCATTTACACCACTATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTGTCAACCATGACCAATCTTTTGCATTTTCTTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGCACTAATGTATTTTTGCAAGGGCTGGCCCAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATATGAAAATTGGTGGTAGAGCTTTATCAAACG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATATTGGTGCTAGAGAATGTACTAGATATATGTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTACTGGATAATATTATTTTAAGTATGGTAAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC

>NC_021184|10|6|4234677-4241878|CRT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTGAGGGCGCAGTCTTGGAGAACTTTAAGCGGAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATAACCGAACACGTCCAGGGGTTCCTCGCAGAAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTAATATTATCCTTGCCGACATCAACCCCGATACC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTTACGTACCCACGAGGTGATGCGCTTGTGTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCGAGGATGCGGCCACAAATCTATTGCAGGAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAATGTGCAGCGGCTTTTGTCAGTTCATAGCTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAATTATAAGCGCCATTGGCGTCGGTGACATCAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACATTTACTGATATGGTACGTGCAAAGGCATCAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TACCAGTACCTTTTAGATCGAGCCACCTGTGGGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGGTATCCTCTCCGCGCAGGCTGCGGGGCATTGAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCATGTAAGACATCTCTCCTTTTAATTAATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CACCGGCTCCGGGCATCGTTGATCCGTTCAATGCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTTCGCCTTTAAAAACATGTTCGTTGAACAGCTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGATCGATATCAATTAGGAAAGGGGGCCGACGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GACAGCACAACGCCGGGATAAATCTTTTTTATAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATACAAACTAGAATGCTTAGTAATATTTCTAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGAACCAGGCAACAACTCGCGCTTCAATCGCGGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCATCAATCGCTCTCATGCTACTGCCAATCTGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGACAGCTTATATGGACGGCATGGCGGTGGCAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGGTAAATTTCTCTTGTGTATTATGATTTATGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCTAGTATTGTACGACCAACAAAGTCACAAGTTGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGTGGATAATAGTATGGCCATGAGGAATAGGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTGTTTGGCTTATGCTTATTGGTTAAGTCAAACAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTGAGGACATGCGCGAAGATGTAAAGGAAATCAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGGATGCAATCAATCAACTAAAAGCCAGTGGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACGGTGAGGGGGAAAGTAAAAGATGAAAATAGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACCTCGGACGCACGATTAAAGCTTTGTTTAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTAGCCATTTGCAGCAGATTGTCTGCGGGTATTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATGCGTTTGTGATGCAGTGGGGGCTGAGATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATCGCTTTTCGGAACCCAAGCCCAAGCGAGATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACAAATCATAGCCGAGCTGCAGCGGCGGGAGCAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCCAATGCGCCCGCAATCGGAGCAACGTATTTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTTATGGAGATTATGTGTCGACTGACGGAATGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAT	GGAAATTATCGGCGGTGAAGATGAAATTTTATC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGACATAGATTGCTGGCTGCAGGGTTTATAGTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTTATTTTGTTGAATTGGTTTTTGATATGGCAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCATCGGCGGGCTCTTCATGGATATGGGGACTGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCACTGGCTGTGTATATGCTGGAAGGGAAAAAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTCAACGGTTTCGCCGGGTTTGAATTCCCTGTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCCACCCATGGCCGTTCCGGATCTGGGTTGATGAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTCAGCCGGCCAAATTGCTGACCTGTTAAATCAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAAATGGAGGGAAATACTGTGATTATCGAGAGTAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCAATAGCTTGCTTATGCAGCCCACATAATTCGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTGGGCGTAAAACGCCAAGTGTTTGCATATCTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTTTCACCTCCTCCTGTTCTTTTTCATCCTGACA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGGCACTATACTTGTATCTCATCGAGCAGGGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACTGCAAGCGCCGGGTGGCGGGCGGAAAGGAAGGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTACCCAGACCCGGATAAGAAGCCTATTTTTGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCGTTGGCGTGATCGTTCCCGTATTCGCTAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTGCCTGTCCAGCAAAAATATTTTGCTGCAAAAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGACATAGATTGCTGGCTGCAGGGTTTATAGTGC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATGGCATGAACATGGACGAGTTCTTTTCTGAGCTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTGCCCTATTGGTCGGTCAGTATGTGCATAGTTG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCAACACGGATCGGGGCCTTGTTCATGGAGATGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTATCTGTTTCTTTTTTTGCCTTTTGACCCATCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCTGGCTGTTTATGGCCGCTTCAAGGCGGATAAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCGTATGCAAAGGGTTCACAGCGGAAAGTTATCTC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATCAATAGCGGACGGTAAAGCGATGGTGCAGGTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGGCGAAGTCAGGCAAGACTACGCTGGCATTGCAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAGTCGGAGCCAGTACATCGGCTTTTTAGAATGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCATAAATAAAGTCTTTTGTAAACTGATCACCT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTACAGGAAATACGGGTGTCTAGCTTGATACAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGTTGTACCACCCACAGGATCACCTCCAGGTTCAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AACATAGATTCATCCTCCTTTTGTTTTGTTATAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TCTGACCATAGTTCAAACTGTGCTGCTGTGCCCGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GACCGGGTCCGTATTCTGATCGGCCACAACAAAGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATGGCGCTTCAGGAGATGTTAGACGATTTACTATCTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACTGTACCGCCTCACCTTTAAACCCACCCGGTTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGGCGATGGGCTTCAGACAATGCCAGATGGGCCA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACCTCAATACTTTAATCCAGATGCGGACAATTAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTCTACCTGAGCGCGATCAGCGGTCCTGGTGAAGGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATGCTTTAGATTGAGGTGTTTTAAATGAGTAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTGACACCTGGGGAATGTTCTTCCCTCCTACTATG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GATATTGGAACCAGCGAGTCAAGCGGGGTGTGTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTAGGCAAAGAGTATCTGTCCGAGTTTATTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGACTATATGTACAAGAAAGGTATGGGATTACAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CGGAATAGCTCTAACGCCGGGAGATTACTTTTACG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTGCCGCAGGTACCGCCAAGTCTGAACGTATGGAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCAACGCGCAACTCTTTCATTTGTTGTAGATTGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTATAGAGGAAATACAGGTGTCAGAACAACTAAGT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATCCGACATTGGAACTAGCCGAGTATACCAGTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CATAAAAGAATTCGCCGAAGATACTGGTATAGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATCAACTAACTAATTAAGGAGTGATCTTTTTGAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ACGTTAACTATTTTATTATTTTCATTTAATGTAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCGTATCTGTGTTGGCCTAGTTTTCTTCCAAAGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GCCATTGAGGCCCGGGTGATTGCATGGCTTGCCGGA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGTTAAAAGCCAAACTGTACGACCACATGGTAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATAGTTAGGCTCCTTTTCAATTAATTTTAAGGAG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTAAAAATTCTTTTCTATTATCATTTTTATTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGCTTCTTTTTGGTGCTCTTTATCTAACATCCG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GGAATTTCATTATGCACACCACCTTCAATTTAAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CCTTTGGCCGTTTTAACCAGCAAAAAGGCAAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTATCCACAAAGGCACAGCAACCGATTGCTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTATACTCCAACAACTTTTCATATTCTACTTTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TTTCCAATTAGAATCTTGAAAACTAGCAGACATA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTCATCTGCTTTTTTCTTATTTTCAATCCAAATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TATGTGATATAATGGTTTCGCTGAGTATGTGAGG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGGTTCCGGGCCTGGAGGTACGCCCGGCGATGCCG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	CTTTATTTTTATTTGTTTTTGTATTTATTTATTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGTGAAGATTTTGATGGGTTAATTTTAGCATTA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GAGTACTGCCGGCAGGATGTTGTCACAGAAATG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AGCCCATGGGATGGCCAACACCTGGGACGAAATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	TGGAAAAGATGCTAACAGCATTTACACCACTATT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	GTGTCAACCATGACCAATCTTTTGCATTTTCTTT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AAGCACTAATGTATTTTTGCAAGGGCTGGCCCAC
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	AATATGAAAATTGGTGGTAGAGCTTTATCAAACG
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATATTGGTGCTAGAGAATGTACTAGATATATGTAT
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC	ATTACTGGATAATATTATTTTAAGTATGGTAAAAA
GTTTCAATCCACGCCCCCGCGCGGGGGGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_021184.1\|WP_006521545.1\|4233465_4233951_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223550
NC_021184.1\|WP_006521550.1\|4229563_4230274_-\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|132349
NC_021184.1\|WP_006521551.1\|4229283_4229562_-\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|132365
NC_021184.1\|WP_006521549.1\|4230257_4230584_-\|ATP-synthase-subunit-I	unknown	unknown	gnl\|CDD\|379002
NC_021184.1\|WP_006521529.1\|4250654_4252256_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NC_021184.1\|WP_006521553.1\|4226958_4228476_-\|alternate-F1F0-ATPase,-F1-subunit-alpha	unknown	unknown	gnl\|CDD\|236448
NC_021184.1\|WP_006521548.1\|4230808_4231120_-\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|131285
NC_021184.1\|WP_041285008.1\|4242046_4242337_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_021184.1\|WP_006521536.1\|4242350_4243382_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_021184.1\|WP_006521528.1\|4252543_4254424_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_021184.1\|WP_006521547.1\|4231112_4231508_-\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|235750
NC_021184.1\|WP_006521533.1\|4244924_4246733_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NC_021184.1\|WP_006521531.1\|4247413_4249615_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_021184.1\|WP_006521535.1\|4243397_4244057_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NC_021184.1\|WP_006521554.1\|4226018_4226957_-\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|274519
NC_021184.1\|WP_006521530.1\|4250180_4250333_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl\|CDD\|378175
NC_021184.1\|WP_006521532.1\|4246729_4247395_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NC_021184.1\|WP_006521534.1\|4244058_4244925_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NC_021184.1\|WP_006521552.1\|4228484_4229276_-\|ATP-synthase-subunit-B	unknown	unknown	gnl\|CDD\|132364
NC_021184.1\|WP_006521546.1\|4231504_4232887_-\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|236447

Protein	Function_ID	Function_description	E-value
NC_021184.1\|WP_006521545.1\|4233465_4233951_-\|hypothetical-protein	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0.00080967
NC_021184.1\|WP_006521550.1\|4229563_4230274_-\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|132349	TIGR03306, altF1_A, alternate F1F0 ATPase, F0 subunit A. A small number of taxonomically diverse prokaryotic species have what appears to be a second ATP synthase, in addition to the normal F1F0 ATPase in bacteria and A1A0 ATPase in archaea. These enzymes use ion gradients to synthesize ATP, and in principle may run in either direction. This model represents the F0 subunit A of this apparent second ATP synthase.	4.90319e-113
NC_021184.1\|WP_006521551.1\|4229283_4229562_-\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|132365	TIGR03322, alt_F1F0_F0_C, alternate F1F0 ATPase, F0 subunit C. A small number of taxonomically diverse prokaryotic species, including Methanosarcina barkeri, have what appears to be a second ATP synthase, in addition to the normal F1F0 ATPase in bacteria and A1A0 ATPase in archaea. These enzymes use ion gradients to synthesize ATP, and in principle may run in either direction. This model represents the F0 subunit C of this apparent second ATP synthase.	7.24441e-37
NC_021184.1\|WP_006521549.1\|4230257_4230584_-\|ATP-synthase-subunit-I	gnl\|CDD\|379002	pfam12966, AtpR, N-ATPase, AtpR subunit. Membrane protein with three predicted transmembrane segments, two of which contain conserved Arg residues. AtpR genes are found in the N-ATPase (archaeal-type F1-Fo-ATPase) operons and are predicted to interact with the conserved Glu/Asp residues in the c subunits, regulating the assembly and/or function of the membrane-embedded ring of 'c' (proteolipid) subunits (pfam00137).	8.5383e-18
NC_021184.1\|WP_006521529.1\|4250654_4252256_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	3.26294e-63
NC_021184.1\|WP_006521553.1\|4226958_4228476_-\|alternate-F1F0-ATPase,-F1-subunit-alpha	gnl\|CDD\|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0
NC_021184.1\|WP_006521548.1\|4230808_4231120_-\|AtpZ/AtpI-family-protein	gnl\|CDD\|131285	TIGR02230, H+-transporting_ATP_synthase_gene_1, F0F1-ATPase subunit, putative. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophic stretches and is presumed to be a subunit of the enzyme. [Energy metabolism, ATP-proton motive force interconversion].	1.22637e-37
NC_021184.1\|WP_041285008.1\|4242046_4242337_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.00886e-36
NC_021184.1\|WP_006521536.1\|4242350_4243382_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	4.59809e-179
NC_021184.1\|WP_006521528.1\|4252543_4254424_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.85528e-59
NC_021184.1\|WP_006521547.1\|4231112_4231508_-\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|235750	PRK06228, PRK06228, F0F1 ATP synthase subunit epsilon; Validated.	3.87725e-59
NC_021184.1\|WP_006521533.1\|4244924_4246733_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NC_021184.1\|WP_006521531.1\|4247413_4249615_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	9.73407e-54
NC_021184.1\|WP_006521535.1\|4243397_4244057_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	2.3547e-29
NC_021184.1\|WP_006521554.1\|4226018_4226957_-\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|274519	TIGR03323, alt_F1F0_F1_gam, alternate F1F0 ATPase, F1 subunit gamma. A small number of taxonomically diverse prokaryotic species, including Methanosarcina barkeri, have what appears to be a second ATP synthase, in addition to the normal F1F0 ATPase in bacteria and A1A0 ATPase in archaea. These enzymes use ion gradients to synthesize ATP, and in principle may run in either direction. This model represents the F1 gamma subunit of this apparent second ATP synthase.	9.92653e-101
NC_021184.1\|WP_006521530.1\|4250180_4250333_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	0.000245254
NC_021184.1\|WP_006521532.1\|4246729_4247395_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.25789e-117
NC_021184.1\|WP_006521534.1\|4244058_4244925_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.464e-160
NC_021184.1\|WP_006521552.1\|4228484_4229276_-\|ATP-synthase-subunit-B	gnl\|CDD\|132364	TIGR03321, alt_F1F0_F0_B, alternate F1F0 ATPase, F0 subunit B. A small number of taxonomically diverse prokaryotic species, including Methanosarcina barkeri, have what appears to be a second ATP synthase, in addition to the normal F1F0 ATPase in bacteria and A1A0 ATPase in archaea. These enzymes use ion gradients to synthesize ATP, CC and in principle may run in either direction. This model represents the F0 subunit B of this apparent second ATP synthase.	3.47939e-73
NC_021184.1\|WP_006521546.1\|4231504_4232887_-\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0

>NC_021184.1|WP_006521545.1|4233465_4233951_-|hypothetical-protein
MFGKSIFFFYKALLFGIAAYAIIPRPEFKKYLIYGFIFGAIGDIIVLLITGPVLNLYKYFHLGPFGIWGIFTFWTPISWMFAFMLFFYFLPVRIPFLLPYVAGFSMFGYMVGLVLQGLGMYEYIGNYIYFAPVTFLIWFSIAAFSYIRIGNIRLNSHLNGE
>NC_021184.1|WP_006521546.1|4231504_4232887_-|F0F1-ATP-synthase-subunit-beta
MNNSAEQAWGVVVSVRGSVVDVRFIGLPALHNLLITGVAGNVLIEVTAHINEEIARGIALTTTQGLARGARVIDTGQPLKAPVGKRLLGRMFNVFGSPIDGKRELSGGEWRSIHQPPVPLSRRVTRSEIFVTGIKAIDVLAPLERGGKAGLFGGAGVGKTVLITEMIHNTAGVHEGVSFFCGIGERCREAEELYREMMAAGVLGNTVMVFAQMNEPPGARFLAGHTALTMAEYFRDDAKQDVLLLIDNIFRFIQAGAEVSGLMGQIPSRVGYQPTLGTELAQLEERICNTATGAITSVQAVYVPADDFTDPSAIHTFAHLSALLVLSRERASEGLYPAIDPLQSGSKMLVPHIVGERHFRIAQQIRKTLAGYKELKDIIAMLGLEELSREDRQTVFRARRLERFLTQPFFTTEQFTGHEGRFVRLEDALEGCERILNDEFTSYPENSLYMIGNVSEASKL
>NC_021184.1|WP_006521547.1|4231112_4231508_-|F0F1-ATP-synthase-subunit-epsilon
MKLKVLLPTEVFLEEEVTKVSAEAENGSFCLLPRHIDFVTAIVPGLVSFITRGGEEVFLAVDSGILVKCGPEVLVSTRRAVRGPVLGELKDTILREFRTIDEREEQARSVMAKLEASFVRRFIKLEEDTRG
>NC_021184.1|WP_006521548.1|4230808_4231120_-|AtpZ/AtpI-family-protein
MAEYHDKDAGKAADDLVRQIQKKEMRKMKARQEQARSIWFGLGMFGMVGWSVTIPALLGVALGVWIDARWPGPFSWTLMLLVGGLLAGCINAWYWVERERKRR
>NC_021184.1|WP_006521549.1|4230257_4230584_-|ATP-synthase-subunit-I
MAVALSWLIIFAVGLGLGLFYFGGLWLTVRRLPVARRPGLLAAGSFVVRTGGCLWGFYLVMAGQWECILACLAGFVTARLILVRQLRPACHTAAIGSGGRGDRDAPES
>NC_021184.1|WP_006521550.1|4229563_4230274_-|F0F1-ATP-synthase-subunit-A
MRLSPDEIIFWHWGPVTLNATIFFTWLVMGVLVLGSWLATRRMTGDFHPTRWQNLLEALVTLMRDQIRDISRQEPGRYLPFVGSLFLFIAASNLLIIIPGYEPPTGSLSTTVALAACVLLSVPFYGVARNGLRGYVKHYIEPSFIMLPFHIIGEFTRTVSLAVRLYGNIMSGSVIIAILLSIAPLFFPIIMQVLGLLVGLIQAYIFAVLAMVYIASAATAHAEKEQAGQQPGKGES
>NC_021184.1|WP_006521551.1|4229283_4229562_-|F0F1-ATP-synthase-subunit-C
MDTLGIIGAVAMIMSGLTISIGSIAPALAEGRAVAQALSAIAQQPDEANTISRTLFVGLAMIESVAIYCFVVSLILIFANPFWNIAVSKMGG
>NC_021184.1|WP_006521552.1|4228484_4229276_-|ATP-synthase-subunit-B
MHVDWFTVLAQVINFLIFVALLKRFLYGPILRNMDQREAGIAARLEKAAQKEKDAGAEAEAFRQKLRELEEQSAAMLASVREEAEALRKDLSNRARNEVNAAQARWYEAFQEQKNTLLLDLRRSAGKQVYAVAKQALRDLAGVKLNQQMIEAFMQQFRAIDPGERSLLAQAIGQSGGVVVLRSAFEIDPEMRAKVDSTIREVIAGDIELRFETVPGLIAGLEMTAHGRQVAWHLDNYLDRLKESFARVLDEEILPEKEEKEAS
>NC_021184.1|WP_006521553.1|4226958_4228476_-|alternate-F1F0-ATPase,-F1-subunit-alpha
MELTTVLNELDRSFETALNRCRAELRGREVGTVTYVSGGIARVEGLPNVQLDELLHFPGELWGMAYNLDPGEVGVVMLGDSGKLKAGDTVLRTGRVLDVPVGEALLGRVVDAIGRPLDSRGPVRARGRRPAEREAPAILDRAPVTVPLQTGLKVVDAMVPVGRGQRELIAGDRQTGKTAIALDTIINQKGKEVLCVYCAVGQRGAAVAKLVSDLQHHGAMDYTTVVVAEGSDPPGLQFITPYAATTMAEYFMEQGCDVLIVYDDLTRHAQAYRELSLLLRRPPGREAFPGDIFYIHSRLLERSTHLREQRGGGSLTALPIIETEAQNLAAYIPTNLISITDGQIYLSPDLFQKGVLPAVDVGKSVSRVGGKTQLPAYRAVAGDLRLSYAQFEELEVFSRFSMRLDESTRKTLERGWRVREILKQPQYAPIPVPEQIAVLLAVTGGSFDELPLDRIGEAALALTRAVAEEMPALSRHIESGEKIRNEDRQALLEKALRVVHMIVEE
>NC_021184.1|WP_006521554.1|4226018_4226957_-|F0F1-ATP-synthase-subunit-gamma
MQTLEHIRGAIAGMEDLQAVVRTMKTLAAVSIRQYERAAGALNDYFRTIELGLYVVLKEGLYEAAAQAGQPKEGLVAVVMGSDQGLCGRFNDQIAAYALETMAQLEPRRERRAVICVGARAHVHLEEAGQPVTALFSVPESLQGVTAAVQDLLAKLEELHGQGRVERVTLFFNVPQSGASYRPLARHLLPLDQAWLHALTRRNWPNRVLPVFTMDQERLFASLVREYLFMSIYRALVESLAGENASRLASMQVAERNIGERLDELHAVYRHRRQSAITEELLDIVAGREASTQGTPKYSSAGKRSAFDSAFL
>NC_021184.1|WP_041285008.1|4242046_4242337_-|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVSTTTEAGKKRLRHVAKQCVNYGQRVQNSVFECLLDPAQFAALKNKLEGIINKDEDSLRYYFLGSNWKRRVEHVGARQTFDPEGTIIV
>NC_021184.1|WP_006521536.1|4242350_4243382_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKMLNVLYVTNPEAYLVKDGENLVVRIQDQEAFRTPIHYLEGIVTFGYMGASPALLGMCVEKGVTVSFLTASGKHQATVHGSPKGNVLLRRKQYRLADSDHDSAQIASMFIIGKLANCRTVLRRFISDYGEKVDAAQVVNVSKILARNVLRVNKEIHLDEVRGIEGESAREYFSVLNHLIVAQKEYFYIQGRNRRPPLDNFNALLSFLYSLLLHEARAALETVGLDPYVGFLHRDRPGRVGLALDLMEEFRPYMADRLALSLINRRQVTGDGFIKKESGGVVMKDTARKAVIEAWQKRKREEITHPFLNKKIPAGLLPYAQALLLARHLRGDLDRYPPFVWK
>NC_021184.1|WP_006521535.1|4243397_4244057_-|CRISPR-associated-protein-Cas4
MKKYDQEEDLLSLSGIQHFAFCERQWALIHVENQWVDNVRTVEGKILHQRADDPYFTEVRGDVKTIRSVPLVSKTLGLYGVADVIELHKLPKSKTNHSYSIVEYKRGKPKPDDRDEVQLCAQAICLEEMLDIQLEYGYLYYGETKRRHKVQFDDFLRGRVKELADKMHQNFARGITPLPVKDKRCKNCSMAGICVPDLAKGNKKAEKYLTGLFDEMANE
>NC_021184.1|WP_006521534.1|4244058_4244925_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MAEAIKNRYEFVLLFDVENGNPNGDPDAGNMPRIDAETGLGLVTDVCLKRKIRNYVDIARGGNEGYDIYVREGAVLNVQHKKAYEHYELKPESKKLPKNEADAKKVTDFMCHHFYDIRSFGAVMTTEVNCGQVRGPVQINFARSMDPIIQQEITITRMAVTSEKDAEKKDREMGRKHIVPYGLYRAEGFVSANLAQKTGFTTDDLELLWEALINMFDHDRSAARGKMAARKLVIFEHETALGNAPAHKLFELVTVAKKDLTRPARAYSDYEVTVNAAAVPAGVKLTEK
>NC_021184.1|WP_006521533.1|4244924_4246733_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MIINALYRHYETLLNDPDSGVSRPGFNKVKVGYCLVLSRQGRLLDILDLRVERDKKLVSRDMTVPEQGKRAVNIFANFLCDNCTYVLGLGQKGKTVKLDRIKKCFQEFVQKHDQILGNVADEGATALLEFLHSWDITGALEHPVISRHIDELSEGLNLVFKLEGATGYLHENKAMVDAWEMYRSGQASNINMQCLVTGKDTGIARLHPNIKGVTGAQTSGASLVSFNLDAFTSYGKKQSFNAPVGEEATFGYTTALNYLLSNAKHRVRIGDTTTVFWAECSTGGLEEDLLGALFFPVGEESDAKKEKENKNSFQVVRDPQTVKLMHDIFQRVRAGKPVGQGLVGVNWDTNFYILGLAPNASRLAVRFWHMDPYVKFIEKIGQHYADMAIVKRYDNDPDFISISMLLKETAPLRDTKRIAPLLGGLLMRSILTGMPYSTALYNAIISRIRADQEVNYVRAAAIKAFLARNRRYYNKGNEVDLTVALNESNNNTGYLLGRLFALLEKAQEDANPGINSTIRDRYFGSASASPSSVFPILLRLAQHHISKAEYGRYTDKRIEEVISAIDCFPAYLNIEDQGQFVLGYYQQRQALFIKSEKKESVN
>NC_021184.1|WP_006521532.1|4246729_4247395_-|type-I-C-CRISPR-associated-protein-Cas5
MGYGIRLLVWGNYACFTRPEMKVERVSYDVMTPSAARGILESLHWKPAIKWVVDSILVLNEIRFDNVRRNEVGGKIPAGNVKKAMKGNPMVLCQYASQDRQQRATLLLRNVAYVIEAHFEMTAEAGSQDTPEKHYAIITRRARQGQCFQQPYLGCREFPASFRLIEEGEPLPHSQLRGEQDLGWMLWDIDHGDGMNPLFFRASMKDGLIEVPRVQEGVTVK
>NC_021184.1|WP_006521531.1|4247413_4249615_-|CRISPR-associated-helicase/endonuclease-Cas3
MTYFAHSDKDKPASQWQLLKDHLEHAGETASISAKPWGAEKISYLAGLMHDMGKYSVQFQERLKGRIIKVDHSTAGAVEAEKRYGPVGRILAYIIAGHHCGLPDWGSAADESSLAARLNKRLNDYSAFFREIELPPAGEVSFPAIRPVCGAGFSVQFLIRFLYSCLVDADFLDTEKYACPAKSAARNNQYALGELSSKLDWFLDDMCAKAPDTVVNRWRAQILAHCREKARHASGLFTLTVPTGGGKTLSSLSFALKHALQYGQKRVIYVIPYTSIIEQNADVFRKVLGIEQVLEHHSNFTYPQQDQEDSDTEYASDVGQKLKLAAENWDMPVIATTNVQFFESLFAARSSRCRKIHNIANSVIIIDEAQMIPTGFLKPCLNALSELVTNYKTTIVLCTATQPAIGQLLPNGVKPVEIIGDPDGLYQAFKRVKVCNIGTVVDDDLAERLTAYHQVLCIVNTKKHARLLYEQISAEGTFHLSTRMCPEHRSETLKIIKDRLKKGQVCRVVSTQLIEAGVDVDFPVVYRSMAGIDSIAQSAGRCNREGLLPFGRLFVFWPAEKHGLPRGWLSRTASLGGMVFERLSDPLGLDGVKEYFSSLYDVDTALLDKEGIMAEIKEQEKQLKFPFRTIADKFKIIDKNTVPIIIPWGEACNKTLAQAKFSPFPGTYARKLQRYGVGVYENEFNELVNNQALEVIAETFYVLKEEVFIKYYSRKTGLNPFTESMFLNDTLII
>NC_021184.1|WP_006521530.1|4250180_4250333_+|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MSREEIIAEIERLRARMYDLVDAGANYDDLILASQELDRYIVMYHIAARF
>NC_021184.1|WP_006521529.1|4250654_4252256_-|methyl-accepting-chemotaxis-protein
MKLNIKGKILLGFGVVLLLMLGSCLYLIDKMKTMDDNYSALINEKAYGYIYAESARAGFNMAAVNVRGYIIDGNSDSPAKIQASLDNSIKLIDKIAPLMSTDEGKQLINDYKTKADVYRKLMLDQLVPLISARESAQSEKERAIAQKKITDFFAANQKTITDLDTAAQTFSEYESKLLEEGGNQNTDNVREIITTSNIVVLIIIILGLVIALLIARMIANPISLVDTEAAKIATGDLTGKEIKVRTKDEVGHLAESFNNMLHNLKDITRQLQEKSQKVASSAAELSASAENVSAAATETASTVGEVASTVEQVAANAQHISDVSAQAAAHAKEGNEGLDSVVAQMDIIQETTESSGKVVSGLSESAGKITQIVELITSIADQTNLLALNAAIESARAGEHGRGFAVVADEVRKLAEQSAGAAKEIHILITSIQHESKKAVESMQQSGTQVETGSQVVREVRVTIEKIISAVQNMADDIQSVAVAIEQMNSGVQNVAAATEEQTATMEEVASTTQSLAGLAGELDELSKRFKLA
>NC_021184.1|WP_006521528.1|4252543_4254424_-|methyl-accepting-chemotaxis-protein
MGNSVRFKIIAPITIIISLVLILIIYQDYKNKVAMQLDQESQIYELVAQRVLADMDNVFNQARLGLEAVAANPEIQKAFAEQDREKLLALTLPIYQETSQEGIEQFQFHLAPAISFLRLHQPDKYGDDLSSFRHTVLECNKTGKTVQGLEEGKAGFGFRVVMPVMYQGEQVGSVEYGPGLNATLLEKWQKQMGGDYYIYSKGSSGVSWEDQEGLLVSTTKEDHYSINENDINAVLSAKKAKTFYVDDNRKAALIVPLEDYSGKPVGFIKIINDRSKVITELAGELRFAQVEAVAAVLIILISTLMITTIIIRPLTRLGAVVKAVAEGDLTQQVETVKSKDEVGVLAGAVATMVHNLREIIADIKVYSQRLAAYSQELVSSSEEVSASIEEVASTTSQVSSVSDRCAQGLAVVSQESEQMRQIAEQGNQAVLKTVDKINAIDTASQNVYQTVHKLSEQSNRIGEIISTITNIADRTNLLALNAAIEAARAGEQGRGFAVVAEDVRKLAEQSASAAHEIKVLIKDIQSGVGEAVTAIERGNDEVSGGVQVAGQTGASLSQIIGAVEKNTDMIKQAVAGAMQASEDTRQLSGASDQVVRAIQQVAGAAQNLANLADELQQGIVKFEIED

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021184_10	10.90\|4240623\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240623-4240656	34	MK448467	Streptococcus satellite phage Javan391, complete genome	2478-2511	4	0.882
NC_021184_10	10.90\|4240623\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240623-4240656	34	MK448469	Streptococcus satellite phage Javan396, complete genome	2480-2513	4	0.882
NC_021184_10	10.90\|4240623\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240623-4240656	34	MK448482	Streptococcus satellite phage Javan413, complete genome	2475-2508	4	0.882
NC_021184_10	10.83\|4240157\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240157-4240190	34	MH884513	Bacillus phage vB_BpsS-36, complete genome	1245-1278	6	0.824
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP044538	Borrelia sp. CA690 plasmid lp28-2, complete sequence	11993-12025	6	0.818
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	KX961631	Bacillus phage QCM11, complete genome	879-911	6	0.818
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	MK084630	Bacillus phage StevenHerd11, complete genome	879-911	6	0.818
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	MF156580	Bacillus phage RadRaab, complete genome	880-912	6	0.818
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_031032	Bacillus phage Stitch, complete genome	880-912	6	0.818
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_049966	Bacillus phage vB_BthP-Goe4, complete genome	881-913	6	0.818
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_049963	Bacillus phage Juan, complete genome	901-933	6	0.818
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MF547663	Clostridioides phage LIBA2945, complete genome	125448-125481	6	0.824
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	AP014390	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S44-C9, * SEQUENCING IN PROGRESS *	28836-28869	6	0.824
NC_021184_10	10.41\|4237365\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237365-4237399	35	NC_021336	Bacillus phage MG-B1, complete genome	8088-8122	7	0.8
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP015507	Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence	310800-310834	7	0.8
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP019921	Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence	19597-19629	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP044538	Borrelia sp. CA690 plasmid lp28-2, complete sequence	3570-3602	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_018982	Borrelia burgdorferi 297 plasmid 297_cp32-9, complete sequence	11394-11426	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_017402	Borreliella burgdorferi N40 plasmid N40_cp32-9, complete sequence	19578-19610	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_015911	Borreliella bissettii DN127 plasmid cp9, complete sequence	587-619	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_011779	Borreliella burgdorferi ZS7 plasmid ZS7_lp28-2, complete sequence	4746-4778	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP031406	Borreliella burgdorferi strain MM1 plasmid plsm_cp32-9, complete sequence	19481-19513	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP031411	Borreliella burgdorferi strain MM1 plasmid plsm_cp32-5, complete sequence	7433-7465	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_011722	Borreliella burgdorferi ZS7 plasmid ZS7_cp32-9, complete sequence	19545-19577	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP028863	Borreliella garinii strain 20047 plasmid lp28-4, complete sequence	11909-11941	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_001852	Borreliella burgdorferi B31 plasmid lp28-2, complete sequence	4704-4736	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_000954	Borreliella burgdorferi B31 plasmid cp32-9, complete sequence	19597-19629	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP015799	Borrelia mayonii strain MN14-1539 plasmid cp32-13, complete sequence	18145-18177	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP015800	Borrelia mayonii strain MN14-1539 plasmid cp32-3, complete sequence	19350-19382	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP019850	Borreliella burgdorferi plasmid cp32-9, complete sequence	19526-19558	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP019760	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-9, complete sequence	19597-19629	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_004971	Borrelia burgdorferi 297 plasmid cp18-2, complete sequence	11376-11408	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP031220	Arcobacter mytili LMG 24559 plasmid pAMYT, complete sequence	51976-52008	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP015784	Borrelia mayonii strain MN14-1420 plasmid cp32-3, complete sequence	19350-19382	7	0.788
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP017255	Clostridium taeniosporum strain 1/k plasmid pCt2, complete sequence	31961-31993	7	0.788
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	NC_023007	Bacillus phage vB_BanS-Tsamsa, complete genome	121735-121769	7	0.8
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	MT254578	Bacillus phage Izhevsk, complete genome	119734-119768	7	0.8
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP032824	Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence	22952-22985	7	0.794
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MF547662	Clostridioides phage LIBA6276, complete genome	127183-127216	7	0.794
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP015636	Borrelia turicatae strain BTE5EL plasmid lp48	36287-36320	7	0.794
NC_021184_10	10.16\|4235708\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4235708-4235741	34	KX827371	Staphylococcus phage SpT99F3, complete genome	10646-10679	8	0.765
NC_021184_10	10.16\|4235708\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4235708-4235741	34	MT423824	Staphylococcus virus pSp_SNUABM-S, complete genome	17670-17703	8	0.765
NC_021184_10	10.16\|4235708\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4235708-4235741	34	MT423823	Staphylococcus virus pSp_SNUABM-J, complete genome	18412-18445	8	0.765
NC_021184_10	10.50\|4237963\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237963-4237997	35	NC_011356	Enterobacteria phage YYZ-2008, complete prophage genome	25049-25083	8	0.771
NC_021184_10	10.50\|4237963\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237963-4237997	35	FJ184280	Enterobacteria phage YYZ-2008, complete genome	25049-25083	8	0.771
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP014570	Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence	7693-7727	8	0.771
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	442784-442818	8	0.771
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP016590	Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-02, complete sequence	107882-107916	8	0.771
NC_021184_10	10.88\|4240491\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240491-4240525	35	MK257744	Thermus phage YS40_Isch, complete genome	41067-41101	8	0.771
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_008443	Borrelia burgdorferi strain Ip21 plasmid, complete sequence	4198-4230	8	0.758
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP028875	Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence	3680-3712	8	0.758
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_017419	Borreliella burgdorferi N40 plasmid N40_lp28-2, complete sequence	4842-4874	8	0.758
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP028874	Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence	25810-25842	8	0.758
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP028880	Borreliella bavariensis PBi plasmid cp32-5, complete sequence	7562-7594	8	0.758
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP040513	Bacillus altitudinis strain GQYP101 plasmid unnamed, complete sequence	3024-3056	8	0.758
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP040513	Bacillus altitudinis strain GQYP101 plasmid unnamed, complete sequence	7562-7594	8	0.758
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	NZ_AP018256	Calothrix sp. NIES-4071 plasmid plasmid1 DNA, complete genome	164925-164959	8	0.771
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NC_019688	Clostridium perfringens plasmid pNetB-NE10, complete sequence	35529-35562	8	0.765
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MT074146	Bacteroides phage SJC03, complete genome	31907-31940	8	0.765
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MN693226	Marine virus AFVG_25M419, complete genome	19338-19371	8	0.765
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP009055	Lactococcus lactis subsp. lactis NCDO 2118 plasmid pNCDO2118, complete sequence	23574-23607	8	0.765
NC_021184_10	10.31\|4236706\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4236706-4236739	34	NZ_CP015441	Erythrobacter atlanticus strain s21-N3 plasmid unnamed, complete sequence	76640-76673	9	0.735
NC_021184_10	10.47\|4237765\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237765-4237799	35	NZ_CP021119	Streptomyces sp. CLI2509 strain CLI2905 plasmid unnamed1, complete sequence	130453-130487	9	0.743
NC_021184_10	10.55\|4238296\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4238296-4238329	34	MN694724	Marine virus AFVG_250M441, complete genome	14752-14785	9	0.735
NC_021184_10	10.58\|4238495\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4238495-4238528	34	MG784342	Bacillus phage Carmen17, complete genome	24473-24506	9	0.735
NC_021184_10	10.60\|4238628\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4238628-4238661	34	NZ_CP022266	Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plB, complete sequence	27730-27763	9	0.735
NC_021184_10	10.75\|4239627\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4239627-4239659	33	MK448890	Streptococcus phage Javan264, complete genome	28810-28842	9	0.727
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NC_007720	Aster yellows witches'-broom phytoplasma AYWB plasmid pAYWB-IV, complete sequence	2783-2817	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	37416-37450	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP017574	Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence	23985-24019	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NC_014172	Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequence	307826-307860	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP009595	Bacillus cereus strain 3a plasmid pBFC_3, complete sequence	180863-180897	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP009606	Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence	47098-47132	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP053994	Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence	120869-120903	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP009368	Bacillus cereus strain FM1 plasmid unnamed, complete sequence	131244-131278	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	CP016196	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence	62044-62078	9	0.743
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP053992	Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence	103885-103919	9	0.743
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_LR214943	Mycoplasma orale strain NCTC10112 plasmid 4	3778-3810	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP028875	Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence	20991-21023	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP009068	Borreliella afzelii K78 plasmid cp32-9, complete sequence	19814-19846	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP009069	Borreliella afzelii K78 plasmid cp32-4, complete sequence	19700-19732	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP009070	Borreliella afzelii K78 plasmid cp32-3, complete sequence	19398-19430	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP009071	Borreliella afzelii K78 plasmid cp32-5, complete sequence	19612-19644	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP028871	Borreliella garinii strain 20047 plasmid lp32-10, complete sequence	16564-16596	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_017230	Borreliella afzelii PKo plasmid cp32-1, complete sequence	19687-19719	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_017224	Borreliella afzelii PKo plasmid cp32-11, complete sequence	19842-19874	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NC_017240	Borreliella afzelii PKo plasmid lp32-10, complete sequence	17012-17044	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP018752	Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed5	6615-6647	9	0.727
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	MT774408	CrAssphage cr130_1, complete genome	12871-12903	9	0.727
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	KY065457	Streptococcus phage IPP16, complete genome	18426-18460	9	0.743
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	KY065464	Streptococcus phage IPP23, complete genome	17862-17896	9	0.743
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	KY065467	Streptococcus phage IPP26, complete genome	18001-18035	9	0.743
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_LN774770	Lactococcus piscium MKFS47 plasmid II, complete sequence	53827-53860	9	0.735
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP014520	Borrelia anserina Es isolate UTHSCSA plasmid pB25, complete sequence	16483-16516	9	0.735
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MK249145	Blackfly microvirus SF02 isolate 034, complete genome	4544-4577	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MT108729	Pseudomonas phage Epa22, complete genome	63872-63905	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN871467	UNVERIFIED: Pseudomonas phage Pa-P, complete genome	50682-50715	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN871457	UNVERIFIED: Pseudomonas phage Pa-F, complete genome	41127-41160	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MT933737	Pseudomonas phage PASA16, complete genome	6296-6329	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	KU198331	Pseudomonas phage NP3, complete genome	35418-35451	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN615701	Pseudomonas phage vB_PaeM_SMS21, complete genome	35819-35852	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN131142	Pseudomonas virus PA8P1, complete genome	42050-42083	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	NC_048676	Pseudomonas phage SL1, complete genome	36774-36807	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	GU815091	Pseudomonas phage JG024, complete genome	35427-35460	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MT108727	Pseudomonas phage Epa11, complete genome	20233-20266	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN131141	Pseudomonas virus PaP1_EPu-2019, complete genome	42729-42762	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN615700	Pseudomonas phage vB_PaeM_SMS12, complete genome	35517-35550	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	KR054033	Pseudomonas phage DL68, complete genome	39895-39928	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	LZ998059	JP 2017534684-A/6: Phage Therapy	56132-56165	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	LQ277711	Sequence 6 from Patent WO2016071503	56132-56165	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN871460	UNVERIFIED: Pseudomonas phage Pa-I, complete genome	33231-33264	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	NC_011756	Pseudomonas phage SN, complete genome	35411-35444	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN131143	Pseudomonas virus PA11P1, complete genome	42311-42344	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MN615702	Pseudomonas phage vB_PaeM_SMS29, complete genome	35517-35550	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	MF623055	Pseudomonas phage BrSP1, complete genome	41886-41919	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	NC_050147	Pseudomonas phage Epa13, complete genome	59475-59508	9	0.735
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	KP340287	Pseudomonas phage phiKT28, complete genome	35232-35265	9	0.735
NC_021184_1	1.1\|34039\|34\|NC_021184\|CRISPRCasFinder	34039-34072	34	KF591601	Enterobacteria phage IME_EC2, complete genome	16388-16421	10	0.706
NC_021184_1	1.1\|34039\|34\|NC_021184\|CRISPRCasFinder	34039-34072	34	MN850623	Escherichia phage sortsyn, complete genome	1977-2010	10	0.706
NC_021184_5	5.5\|550668\|36\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	550668-550703	36	KP881232	Sinorhizobium phage phiM9, complete genome	107308-107343	10	0.722
NC_021184_10	10.31\|4236706\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4236706-4236739	34	CP052361	Klebsiella pneumoniae strain D16KP0144 plasmid pD16KP0144-5, complete sequence	4762-4795	10	0.706
NC_021184_10	10.31\|4236706\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4236706-4236739	34	CP052429	Klebsiella pneumoniae strain C16KP0129 plasmid pC16KP0129-2, complete sequence	1481-1514	10	0.706
NC_021184_10	10.31\|4236706\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4236706-4236739	34	NZ_KU295136	Escherichia coli strain BK28610 plasmid pBK28610, complete sequence	14575-14608	10	0.706
NC_021184_10	10.31\|4236706\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4236706-4236739	34	NZ_CP010366	Enterobacter hormaechei subsp. oharae strain 34978 plasmid p34978-13.828kb, complete sequence	4563-4596	10	0.706
NC_021184_10	10.31\|4236706\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4236706-4236739	34	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	157479-157512	10	0.706
NC_021184_10	10.45\|4237633\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237633-4237667	35	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	513353-513387	10	0.714
NC_021184_10	10.49\|4237898\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237898-4237930	33	NC_022995	Burkholderia sp. M701 plasmid pM7012 DNA, complete sequence	507272-507304	10	0.697
NC_021184_10	10.50\|4237963\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237963-4237997	35	NC_014533	Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence	635757-635791	10	0.714
NC_021184_10	10.55\|4238296\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4238296-4238329	34	NZ_CP009059	Borreliella afzelii K78 plasmid lp54, complete sequence	15439-15472	10	0.706
NC_021184_10	10.55\|4238296\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4238296-4238329	34	NZ_CP014118	Staphylococcus epidermidis strain FDAARGOS_153 plasmid unnamed1, complete sequence	15559-15592	10	0.706
NC_021184_10	10.55\|4238296\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4238296-4238329	34	NC_017241	Borreliella afzelii PKo plasmid lp54, complete sequence	15303-15336	10	0.706
NC_021184_10	10.55\|4238296\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4238296-4238329	34	NZ_CP009214	Borreliella afzelii Tom3107 plasmid lp54, complete sequence	42826-42859	10	0.706
NC_021184_10	10.79\|4239892\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4239892-4239925	34	MN693779	Marine virus AFVG_250M346, complete genome	28716-28749	10	0.706
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	CP002509	Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence	89648-89680	10	0.697
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	MN694792	Marine virus AFVG_250M662, complete genome	11840-11872	10	0.697
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	MN694755	Marine virus AFVG_250M800, complete genome	11649-11681	10	0.697
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	MN694757	Marine virus AFVG_250M663, complete genome	11846-11878	10	0.697
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	MN694134	Marine virus AFVG_250M799, complete genome	11657-11689	10	0.697
NC_021184_10	10.89\|4240558\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240558-4240590	33	NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	240042-240074	10	0.697
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	KY065466	Streptococcus phage IPP25, complete genome	17888-17922	10	0.714
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	KY065468	Streptococcus phage IPP27, complete genome	16698-16732	10	0.714
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP045036	Lactobacillus mali strain LM596 plasmid unnamed1, complete sequence	26511-26544	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP045036	Lactobacillus mali strain LM596 plasmid unnamed1, complete sequence	34773-34806	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP018177	Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-1, complete sequence	21924-21957	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP018181	Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-1, complete sequence	53010-53043	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MN693106	Marine virus AFVG_25M218, complete genome	22059-22092	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MN693116	Marine virus AFVG_25M217, complete genome	22818-22851	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP015330	Bacillus filamentosus strain Hbe603 plasmid pBEH8, complete sequence	2892-2925	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP053657	Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence	179190-179223	10	0.706
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	MW084976	Bacillus phage Kirov, complete genome	153739-153772	10	0.706
NC_021184_10	10.102\|4241415\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241415-4241448	34	NZ_CP012644	Rufibacter tibetensis strain 1351 plasmid 1, complete sequence	164713-164746	10	0.706
NC_021184_2	2.42\|532323\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	532323-532356	34	NC_007959	Nitrobacter hamburgensis X14 plasmid 1, complete sequence	114336-114369	11	0.676
NC_021184_10	10.36\|4237035\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4237035-4237068	34	NZ_CP032486	Neokomagataea tanensis strain AH13 = NBRC 106556 plasmid unnamed1, complete sequence	76185-76218	11	0.676
NC_021184_10	10.84\|4240223\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240223-4240257	35	NZ_CP043057	Dolichospermum sp. UHCC 0315A plasmid pUHCC0315a, complete sequence	60649-60683	11	0.686
NC_021184_10	10.94\|4240887\|33\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4240887-4240919	33	NC_019699	Chroococcidiopsis thermalis PCC 7203 plasmid pCHRO.01, complete sequence	202260-202292	11	0.667
NC_021184_10	10.96\|4241018\|35\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241018-4241052	35	MN855726	Bacteriophage sp. isolate 241, complete genome	5903-5937	11	0.686
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	NZ_CP032914	Alteromonas sp. RKMC-009 plasmid unnamed, complete sequence	62885-62918	11	0.676
NC_021184_10	10.99\|4241218\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241218-4241251	34	KF929199	Staphylococcus phage vB_SepS_SEP9, complete genome	62808-62841	11	0.676
NC_021184_10	10.100\|4241284\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241284-4241317	34	NC_015250	Acinetobacter phage 133, complete genome	131526-131559	11	0.676
NC_021184_10	10.106\|4241679\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241679-4241712	34	AP013413	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C48A-MedDCM-OCT-S28-C15	14650-14683	11	0.676
NC_021184_10	10.106\|4241679\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241679-4241712	34	AP013414	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C48A-MedDCM-OCT-S29-C21	7592-7625	11	0.676
NC_021184_10	10.106\|4241679\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241679-4241712	34	AP013672	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C48A-MedDCM-OCT-S38-C24, * SEQUENCING IN PROGRESS *	2482-2515	11	0.676
NC_021184_10	10.106\|4241679\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241679-4241712	34	AP013415	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C48A-MedDCM-OCT-S37-C22	4862-4895	11	0.676
NC_021184_10	10.106\|4241679\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	4241679-4241712	34	AP013671	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C48A-MedDCM-OCT-S33-C18, * SEQUENCING IN PROGRESS *	21460-21493	11	0.676
NC_021184_2	2.2\|529703\|34\|NC_021184\|PILER-CR,CRISPRCasFinder,CRT	529703-529736	34	MN586021	Arthrobacter phage Beagle, complete genome	44516-44549	12	0.647

1. spacer 10.90|4240623|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MK448467 (Streptococcus satellite phage Javan391, complete genome) position: , mismatch: 4, identity: 0.882

tggcttctttttggtgctctttatctaacatccg	CRISPR spacer
tggcttctttttggtgttctttatccaacattct	Protospacer
****************.********.*****.*

2. spacer 10.90|4240623|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MK448469 (Streptococcus satellite phage Javan396, complete genome) position: , mismatch: 4, identity: 0.882

tggcttctttttggtgctctttatctaacatccg	CRISPR spacer
tggcttctttttggtgttctttatccaacattct	Protospacer
****************.********.*****.*

3. spacer 10.90|4240623|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MK448482 (Streptococcus satellite phage Javan413, complete genome) position: , mismatch: 4, identity: 0.882

tggcttctttttggtgctctttatctaacatccg	CRISPR spacer
tggcttctttttggtgttctttatccaacattct	Protospacer
****************.********.*****.*

4. spacer 10.83|4240157|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MH884513 (Bacillus phage vB_BpsS-36, complete genome) position: , mismatch: 6, identity: 0.824

atcaactaactaattaaggagtgatc-tttttgat	CRISPR spacer
gtcaactaattaattaaggagtgattatatatga-	Protospacer
.********.***************. * * ***

5. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044538 (Borrelia sp. CA690 plasmid lp28-2, complete sequence) position: , mismatch: 6, identity: 0.818

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttttatcttcttttatattattatttttattat	Protospacer
**  *  ******* ******.***********

6. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KX961631 (Bacillus phage QCM11, complete genome) position: , mismatch: 6, identity: 0.818

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
taatatcttcttttctattatcactttcattat	Protospacer
* * *  ****************.***.*****

7. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MK084630 (Bacillus phage StevenHerd11, complete genome) position: , mismatch: 6, identity: 0.818

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
taatatcttcttttctattatcactttcattat	Protospacer
* * *  ****************.***.*****

8. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MF156580 (Bacillus phage RadRaab, complete genome) position: , mismatch: 6, identity: 0.818

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
taatatcttcttttctattatcactttcattat	Protospacer
* * *  ****************.***.*****

9. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_031032 (Bacillus phage Stitch, complete genome) position: , mismatch: 6, identity: 0.818

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
taatatcttcttttctattatcactttcattat	Protospacer
* * *  ****************.***.*****

10. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_049966 (Bacillus phage vB_BthP-Goe4, complete genome) position: , mismatch: 6, identity: 0.818

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
taatatcttcttttctattatcactttcattat	Protospacer
* * *  ****************.***.*****

11. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_049963 (Bacillus phage Juan, complete genome) position: , mismatch: 6, identity: 0.818

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
taatatcttcttttctattatcactttcattat	Protospacer
* * *  ****************.***.*****

12. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 6, identity: 0.824

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tttttaatatatttgtttttgtatttatttgttt	Protospacer
.***   * *********************.***

13. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to AP014390 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S44-C9, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.824

--ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
gacatta--tttatttgtttttttatttatttcttg	Protospacer
  * ***  ************* ********* **

14. spacer 10.41|4237365|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_021336 (Bacillus phage MG-B1, complete genome) position: , mismatch: 7, identity: 0.8

gtcagccggccaaattgctgacctgttaaatcaat	CRISPR spacer
gttaatcttccaaatttttgacctgttaaatcaat	Protospacer
**.*..*  ******* .*****************

15. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015507 (Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence) position: , mismatch: 7, identity: 0.8

--acgttaactattttattattttcatttaatgtaat	CRISPR spacer
tgaagtt--caattttataatgttcatttaatgtaaa	Protospacer
  * ***  * ******* ** **************

16. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019921 (Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

17. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044538 (Borrelia sp. CA690 plasmid lp28-2, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttttttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

18. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_018982 (Borrelia burgdorferi 297 plasmid 297_cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

19. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_017402 (Borreliella burgdorferi N40 plasmid N40_cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

20. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_015911 (Borreliella bissettii DN127 plasmid cp9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttttttcttcttttttattattatttttattat	Protospacer
**     *******.******.***********

21. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_011779 (Borreliella burgdorferi ZS7 plasmid ZS7_lp28-2, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttatattattatttttattat	Protospacer
**     ******* ******.***********

22. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031406 (Borreliella burgdorferi strain MM1 plasmid plsm_cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

23. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031411 (Borreliella burgdorferi strain MM1 plasmid plsm_cp32-5, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

24. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_011722 (Borreliella burgdorferi ZS7 plasmid ZS7_cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

25. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028863 (Borreliella garinii strain 20047 plasmid lp28-4, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttttttcttcttttatattattatttttattat	Protospacer
**     ******* ******.***********

26. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_001852 (Borreliella burgdorferi B31 plasmid lp28-2, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttatattattatttttattat	Protospacer
**     ******* ******.***********

27. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_000954 (Borreliella burgdorferi B31 plasmid cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

28. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015799 (Borrelia mayonii strain MN14-1539 plasmid cp32-13, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

29. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015800 (Borrelia mayonii strain MN14-1539 plasmid cp32-3, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

30. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019850 (Borreliella burgdorferi plasmid cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

31. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019760 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-9, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

32. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_004971 (Borrelia burgdorferi 297 plasmid cp18-2, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

33. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031220 (Arcobacter mytili LMG 24559 plasmid pAMYT, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatt--tttattat	CRISPR spacer
ttaaaacttcttttctattatcatcaacccatt--	Protospacer
****** *****************.  ...***

34. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015784 (Borrelia mayonii strain MN14-1420 plasmid cp32-3, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttgtattattatttttattat	Protospacer
**     ******* ******.***********

35. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017255 (Clostridium taeniosporum strain 1/k plasmid pCt2, complete sequence) position: , mismatch: 7, identity: 0.788

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
atcaatttttttttctattataatttttattct	Protospacer
 * **  **.*********** ********* *

36. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_023007 (Bacillus phage vB_BanS-Tsamsa, complete genome) position: , mismatch: 7, identity: 0.8

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
cttcttctgcttttttcttatcttcaatttctttt	Protospacer
**** ****************.******..   **

37. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT254578 (Bacillus phage Izhevsk, complete genome) position: , mismatch: 7, identity: 0.8

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
cttcttctgcttttttcttatcttcaatttctttt	Protospacer
**** ****************.******..   **

38. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032824 (Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence) position: , mismatch: 7, identity: 0.794

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
taattcttttatttggttttgtatttatatattt	Protospacer
.  * .********* ************ *****

39. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 7, identity: 0.794

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tctttaatatatttgtttttgtatttatttgttt	Protospacer
..**   * *********************.***

40. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015636 (Borrelia turicatae strain BTE5EL plasmid lp48) position: , mismatch: 7, identity: 0.794

ctttatttttatttgtttttgtatttatttattt-	CRISPR spacer
ttttattttttattgtttttgta-ttattgatact	Protospacer
.*********  *********** ***** ** .

41. spacer 10.16|4235708|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KX827371 (Staphylococcus phage SpT99F3, complete genome) position: , mismatch: 8, identity: 0.765

---aatacaaactagaatgcttagtaatatttctagt	CRISPR spacer
ttagatgcga---agaatgcttagcaatatatctagt	Protospacer
   .**.*.*   ***********.***** ******

42. spacer 10.16|4235708|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT423824 (Staphylococcus virus pSp_SNUABM-S, complete genome) position: , mismatch: 8, identity: 0.765

---aatacaaactagaatgcttagtaatatttctagt	CRISPR spacer
ttagatgcga---agaatgcttagcaatatatctagt	Protospacer
   .**.*.*   ***********.***** ******

43. spacer 10.16|4235708|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT423823 (Staphylococcus virus pSp_SNUABM-J, complete genome) position: , mismatch: 8, identity: 0.765

---aatacaaactagaatgcttagtaatatttctagt	CRISPR spacer
ttagatgcga---agaatgcttagcaatatatctagt	Protospacer
   .**.*.*   ***********.***** ******

44. spacer 10.50|4237963|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_011356 (Enterobacteria phage YYZ-2008, complete prophage genome) position: , mismatch: 8, identity: 0.771

ttgcctgtccagcaaaaatattttgctgcaaaaat	CRISPR spacer
tcgacagataagcagaaatattttgctgaaaaaat	Protospacer
*.* * * . ****.************* ******

45. spacer 10.50|4237963|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to FJ184280 (Enterobacteria phage YYZ-2008, complete genome) position: , mismatch: 8, identity: 0.771

ttgcctgtccagcaaaaatattttgctgcaaaaat	CRISPR spacer
tcgacagataagcagaaatattttgctgaaaaaat	Protospacer
*.* * * . ****.************* ******

46. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014570 (Campylobacter fetus subsp. venerealis strain 01/165 plasmid mp2, complete sequence) position: , mismatch: 8, identity: 0.771

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
acaataggtatttttttatttttatttaatgtaga	Protospacer
**. **. ****** *******.**********.

47. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 8, identity: 0.771

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
cccttttttcttttattattttaacttaatgtaat	Protospacer
 * **  .* ************ *.**********

48. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016590 (Bacillus thuringiensis strain KNU-07 plasmid pBTKNU07-02, complete sequence) position: , mismatch: 8, identity: 0.771

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
cccttttttcttttattattttaacttaatgtaat	Protospacer
 * **  .* ************ *.**********

49. spacer 10.88|4240491|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MK257744 (Thermus phage YS40_Isch, complete genome) position: , mismatch: 8, identity: 0.771

-aatagttaggctccttttcaattaattttaaggag	CRISPR spacer
ccata-ttaagctctttttcaattaattttatcaat	Protospacer
  *** ***.****.****************  .*

50. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_008443 (Borrelia burgdorferi strain Ip21 plasmid, complete sequence) position: , mismatch: 8, identity: 0.758

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattat	Protospacer
*.     ******* ******.***********

51. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028875 (Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence) position: , mismatch: 8, identity: 0.758

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tattttcttcttttatattattatttttattat	Protospacer
*      ******* ******.***********

52. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_017419 (Borreliella burgdorferi N40 plasmid N40_lp28-2, complete sequence) position: , mismatch: 8, identity: 0.758

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttctttcttcttttatattattatttttattac	Protospacer
**     ******* ******.**********.

53. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028874 (Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence) position: , mismatch: 8, identity: 0.758

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tttcttcttcttttttattattatttttattac	Protospacer
**     *******.******.**********.

54. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028880 (Borreliella bavariensis PBi plasmid cp32-5, complete sequence) position: , mismatch: 8, identity: 0.758

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttttttcttcttttatattattatttttattac	Protospacer
**     ******* ******.**********.

55. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040513 (Bacillus altitudinis strain GQYP101 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
attagcctgcttttctattattattattattat	Protospacer
 * *.  * ************.*** *******

56. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040513 (Bacillus altitudinis strain GQYP101 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
attagcctgcttttctattattattattattat	Protospacer
 * *.  * ************.*** *******

57. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018256 (Calothrix sp. NIES-4071 plasmid plasmid1 DNA, complete genome) position: , mismatch: 8, identity: 0.771

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
cagtttctgcttttttgttattttcaatacaatta	Protospacer
*  . *********** *********** *** *

58. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_019688 (Clostridium perfringens plasmid pNetB-NE10, complete sequence) position: , mismatch: 8, identity: 0.765

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
ctttatttttagttgtttatgtatttaaagacaa	Protospacer
*********** ****** ********   *.

59. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 8, identity: 0.765

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
attaaaatttatttgtatttttatttatttataa	Protospacer
 ** *  ********* *** ***********

60. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN693226 (Marine virus AFVG_25M419, complete genome) position: , mismatch: 8, identity: 0.765

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
ttttttctttatttgtttttgtatttgtaaatca	Protospacer
.*** *.*******************.*  **.

61. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009055 (Lactococcus lactis subsp. lactis NCDO 2118 plasmid pNCDO2118, complete sequence) position: , mismatch: 8, identity: 0.765

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
agttctttttatttgtttttttatttaaaccttt	Protospacer
  ** *************** ******  . ***

62. spacer 10.31|4236706|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015441 (Erythrobacter atlanticus strain s21-N3 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

acaaatcatagccgagctgcagcggcgggagcag	CRISPR spacer
cgaaatcatagccgcgctgctgcggcggtaagtc	Protospacer
  ************ ***** ******* *.

63. spacer 10.47|4237765|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021119 (Streptomyces sp. CLI2509 strain CLI2905 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

actgcaagcgccgggtggcgggcggaaaggaaggt	CRISPR spacer
ggcggaagcgccgcgaggcgggcggaaagggtggc	Protospacer
. .* ******** * **************. **.

64. spacer 10.55|4238296|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN694724 (Marine virus AFVG_250M441, complete genome) position: , mismatch: 9, identity: 0.735

gtatctgtttctttttttgccttttgacccatca	CRISPR spacer
ttgcattcttctttcttttccttttgacccatcc	Protospacer
 *.. * .******.*** **************

65. spacer 10.58|4238495|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MG784342 (Bacillus phage Carmen17, complete genome) position: , mismatch: 9, identity: 0.735

atcaatagcggacggtaaagcgatggtgcaggtt	CRISPR spacer
tcctactacggacggtacagcgatggtacaggta	Protospacer
 .* *. .********* *********.*****

66. spacer 10.60|4238628|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022266 (Xanthomonas citri pv. vignicola strain CFBP7111 plasmid plB, complete sequence) position: , mismatch: 9, identity: 0.735

gagtcggagccagtacatcggcttttt-----agaatgt	CRISPR spacer
ccatcggagccagtacatcggcgttttcatcgag-----	Protospacer
  .******************* ****     **

67. spacer 10.75|4239627|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MK448890 (Streptococcus phage Javan264, complete genome) position: , mismatch: 9, identity: 0.727

gtaggcaaagagtatctgtccgagtttatttta	CRISPR spacer
ccaccaccagagtatatgtccaagtttatttta	Protospacer
 .*     ******* *****.***********

68. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_007720 (Aster yellows witches'-broom phytoplasma AYWB plasmid pAYWB-IV, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
tctttaactaatttattattgtcatttaattgttc	Protospacer
 * ******* ********* *********    .

69. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043848 (Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
actaaaactatttttttattttcatttaatagctc	Protospacer
**   ********* ***************.   .

70. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017574 (Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
tcctttttccttttattattttgacttaatgtaat	Protospacer
 * **  .. ************ *.**********

71. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_014172 (Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
ccctttttccttttattattttaacttaatgtaat	Protospacer
 * **  .. ************ *.**********

72. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009595 (Bacillus cereus strain 3a plasmid pBFC_3, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
ccctttttccttttattattttaacttaatgtaat	Protospacer
 * **  .. ************ *.**********

73. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009606 (Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
ccctttttccttttattattttaacttaatgtaat	Protospacer
 * **  .. ************ *.**********

74. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053994 (Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
ccctttttccttttattattttaacttaatgtaat	Protospacer
 * **  .. ************ *.**********

75. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009368 (Bacillus cereus strain FM1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
ccctttttccttttattattttaacttaatgtaat	Protospacer
 * **  .. ************ *.**********

76. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to CP016196 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-2, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
tcctttttccttttattattttaaattaatgtaat	Protospacer
 * **  .. ************ * **********

77. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053992 (Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.743

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
ccctttttccttttattattttaacttaatgtaat	Protospacer
 * **  .. ************ *.**********

78. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214943 (Mycoplasma orale strain NCTC10112 plasmid 4) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
cccttaattcttgtatattatcatttttattta	Protospacer
..   ******* * ****************

79. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028875 (Borreliella bavariensis PBi plasmid lp28-4_cp32-1, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tctttttttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

80. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009068 (Borreliella afzelii K78 plasmid cp32-9, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

81. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009069 (Borreliella afzelii K78 plasmid cp32-4, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

82. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009070 (Borreliella afzelii K78 plasmid cp32-3, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

83. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009071 (Borreliella afzelii K78 plasmid cp32-5, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

84. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028871 (Borreliella garinii strain 20047 plasmid lp32-10, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttttattattatttttattac	Protospacer
*.     *******.******.**********.

85. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_017230 (Borreliella afzelii PKo plasmid cp32-1, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

86. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_017224 (Borreliella afzelii PKo plasmid cp32-11, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

87. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_017240 (Borreliella afzelii PKo plasmid lp32-10, complete sequence) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttatattattatttttattac	Protospacer
*.     ******* ******.**********.

88. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018752 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed5) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tcttttcttcttttttattattatttttattac	Protospacer
*.     *******.******.**********.

89. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT774408 (CrAssphage cr130_1, complete genome) position: , mismatch: 9, identity: 0.727

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
attcaaattcttttcttatatcattttttatgc	Protospacer
 *  ************  **********  *..

90. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KY065457 (Streptococcus phage IPP16, complete genome) position: , mismatch: 9, identity: 0.743

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
tagtcacggtttttttcttattttcaatcaaaatt	Protospacer
.  .  * *.******************* *****

91. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KY065464 (Streptococcus phage IPP23, complete genome) position: , mismatch: 9, identity: 0.743

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
tagtcacggtttttttcttattttcaatcaaaatt	Protospacer
.  .  * *.******************* *****

92. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KY065467 (Streptococcus phage IPP26, complete genome) position: , mismatch: 9, identity: 0.743

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
tagtcacggtttttttcttattttcaatcaaaatt	Protospacer
.  .  * *.******************* *****

93. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN774770 (Lactococcus piscium MKFS47 plasmid II, complete sequence) position: , mismatch: 9, identity: 0.735

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
taaacaatttatttgtttatttatttatttattt	Protospacer
.      *********** * *************

94. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014520 (Borrelia anserina Es isolate UTHSCSA plasmid pB25, complete sequence) position: , mismatch: 9, identity: 0.735

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
ttttatttttatttatttttgtgtttggtgttca	Protospacer
.*************.*******.***. *  *.

95. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MK249145 (Blackfly microvirus SF02 isolate 034, complete genome) position: , mismatch: 9, identity: 0.735

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tctattttttatttgtttttgttttttttctatt	Protospacer
..*  ***************** *** **.  **

96. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT108729 (Pseudomonas phage Epa22, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

97. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN871467 (UNVERIFIED: Pseudomonas phage Pa-P, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

98. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN871457 (UNVERIFIED: Pseudomonas phage Pa-F, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

99. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT933737 (Pseudomonas phage PASA16, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

100. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KU198331 (Pseudomonas phage NP3, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

101. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN615701 (Pseudomonas phage vB_PaeM_SMS21, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

102. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN131142 (Pseudomonas virus PA8P1, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

103. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_048676 (Pseudomonas phage SL1, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

104. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to GU815091 (Pseudomonas phage JG024, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

105. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MT108727 (Pseudomonas phage Epa11, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

106. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN131141 (Pseudomonas virus PaP1_EPu-2019, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

107. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN615700 (Pseudomonas phage vB_PaeM_SMS12, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

108. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KR054033 (Pseudomonas phage DL68, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggcctcgccgg----	Protospacer
 ***** *** **************    * **.

109. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to LZ998059 (JP 2017534684-A/6: Phage Therapy) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

110. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to LQ277711 (Sequence 6 from Patent WO2016071503) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

111. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN871460 (UNVERIFIED: Pseudomonas phage Pa-I, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

112. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_011756 (Pseudomonas phage SN, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

113. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN131143 (Pseudomonas virus PA11P1, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

114. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN615702 (Pseudomonas phage vB_PaeM_SMS29, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

115. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MF623055 (Pseudomonas phage BrSP1, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

116. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_050147 (Pseudomonas phage Epa13, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

117. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KP340287 (Pseudomonas phage phiKT28, complete genome) position: , mismatch: 9, identity: 0.735

agcccatgggatggccaacacctgg----gacgaaatt	CRISPR spacer
cgcccaagggttggccaacacctggccgcgccgg----	Protospacer
 ***** *** **************    * **.

118. spacer 1.1|34039|34|NC_021184|CRISPRCasFinder matches to KF591601 (Enterobacteria phage IME_EC2, complete genome) position: , mismatch: 10, identity: 0.706

cctttccattccggcgaatttgccggattgctct	CRISPR spacer
gctttccactccggcgagtttgccgccgcttcct	Protospacer
 *******.********.*******   . ..**

119. spacer 1.1|34039|34|NC_021184|CRISPRCasFinder matches to MN850623 (Escherichia phage sortsyn, complete genome) position: , mismatch: 10, identity: 0.706

cctttccattccggcgaatttgccggattgctct	CRISPR spacer
gctttccactccggcgagtttgccgccgcttcct	Protospacer
 *******.********.*******   . ..**

120. spacer 5.5|550668|36|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KP881232 (Sinorhizobium phage phiM9, complete genome) position: , mismatch: 10, identity: 0.722

attgatatggaaacaggagaaagaaaaaagaatgaa	CRISPR spacer
aagtcaatggaaacaagagaaagaaacaagaaatga	Protospacer
*     *********.********** *****  .*

121. spacer 10.31|4236706|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to CP052361 (Klebsiella pneumoniae strain D16KP0144 plasmid pD16KP0144-5, complete sequence) position: , mismatch: 10, identity: 0.706

acaaatcatagccgagctgcagcggcgggagcag	CRISPR spacer
ccggcaggaagccgagcagcagcggcaggagcag	Protospacer
 *..   . ******** ********.*******

122. spacer 10.31|4236706|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to CP052429 (Klebsiella pneumoniae strain C16KP0129 plasmid pC16KP0129-2, complete sequence) position: , mismatch: 10, identity: 0.706

acaaatcatagccgagctgcagcggcgggagcag	CRISPR spacer
ccggcaggaagccgagcagcagcggcaggagcag	Protospacer
 *..   . ******** ********.*******

123. spacer 10.31|4236706|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KU295136 (Escherichia coli strain BK28610 plasmid pBK28610, complete sequence) position: , mismatch: 10, identity: 0.706

acaaatcatagccgagctgcagcggcgggagcag	CRISPR spacer
ccggcaggaagccgagcagcagcggcaggagcag	Protospacer
 *..   . ******** ********.*******

124. spacer 10.31|4236706|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010366 (Enterobacter hormaechei subsp. oharae strain 34978 plasmid p34978-13.828kb, complete sequence) position: , mismatch: 10, identity: 0.706

acaaatcatagccgagctgcagcggcgggagcag	CRISPR spacer
ccggcaggaagccgagcagcagcggcaggagcag	Protospacer
 *..   . ******** ********.*******

125. spacer 10.31|4236706|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

acaaatcatagccgagctgcagcggcgggagcag	CRISPR spacer
actcgcgcaggccgagctggagcggcgcgagcag	Protospacer
**  ..   .********* ******* ******

126. spacer 10.45|4237633|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 10, identity: 0.714

ggtttcacctcctcctgttctttttcatcctgaca	CRISPR spacer
cgcagatcctcgtcctgttcttcttcatcctgatg	Protospacer
 *.    **** **********.**********..

127. spacer 10.49|4237898|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_022995 (Burkholderia sp. M701 plasmid pM7012 DNA, complete sequence) position: , mismatch: 10, identity: 0.697

gcgttggcgtgatcgttcccgtattcgctaaat	CRISPR spacer
tcgttggcgtgcttgttcccgtattgcttttca	Protospacer
 ********** *.***********  .*

128. spacer 10.50|4237963|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_014533 (Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence) position: , mismatch: 10, identity: 0.714

-------ttgcctgtccagcaaaaatattttgctgcaaaaat	CRISPR spacer
gacgagagtg-------agcaaaaatattttggtgaaaaaat	Protospacer
        **       *************** ** ******

129. spacer 10.55|4238296|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009059 (Borreliella afzelii K78 plasmid lp54, complete sequence) position: , mismatch: 10, identity: 0.706

gtatctgtttctttttttgccttttgacccatca	CRISPR spacer
ttacaaatttctttttttgccctttgaaccaatt	Protospacer
 **.  .**************.***** *** .

130. spacer 10.55|4238296|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014118 (Staphylococcus epidermidis strain FDAARGOS_153 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

gtatctgtttctttttttgccttttgacccatca	CRISPR spacer
ttatctgattcttttttttccttttcttctgtag	Protospacer
 ****** ********** ******  .*..* .

131. spacer 10.55|4238296|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_017241 (Borreliella afzelii PKo plasmid lp54, complete sequence) position: , mismatch: 10, identity: 0.706

gtatctgtttctttttttgccttttgacccatca	CRISPR spacer
ttacaaatttctttttttgccctttgaaccaatt	Protospacer
 **.  .**************.***** *** .

132. spacer 10.55|4238296|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009214 (Borreliella afzelii Tom3107 plasmid lp54, complete sequence) position: , mismatch: 10, identity: 0.706

gtatctgtttctttttttgccttttgacccatca	CRISPR spacer
ttacaaatttctttttttgccctttgaaccaatt	Protospacer
 **.  .**************.***** *** .

133. spacer 10.79|4239892|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN693779 (Marine virus AFVG_250M346, complete genome) position: , mismatch: 10, identity: 0.706

gcaacgcgcaactctttcatttgttgtagattgt	CRISPR spacer
aaaagttacaactgttgcatttgttgtagattcc	Protospacer
. **  ..***** ** *************** .

134. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to CP002509 (Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence) position: , mismatch: 10, identity: 0.697

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tatccaatttttttctatcatcatttttaaccc	Protospacer
*    ****.********.********** . .

135. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN694792 (Marine virus AFVG_250M662, complete genome) position: , mismatch: 10, identity: 0.697

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttaaaaattcttttatattttcatcagatacgt	Protospacer
************** **** ****.     ..*

136. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN694755 (Marine virus AFVG_250M800, complete genome) position: , mismatch: 10, identity: 0.697

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttaaaaattcttttatattttcatcagatacgt	Protospacer
************** **** ****.     ..*

137. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN694757 (Marine virus AFVG_250M663, complete genome) position: , mismatch: 10, identity: 0.697

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttaaaaattcttttatattttcatcagatacgt	Protospacer
************** **** ****.     ..*

138. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN694134 (Marine virus AFVG_250M799, complete genome) position: , mismatch: 10, identity: 0.697

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
ttaaaaattcttttatattttcatcagatacgt	Protospacer
************** **** ****.     ..*

139. spacer 10.89|4240558|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043831 (Bacillus sp. BS98 plasmid unnamed1) position: , mismatch: 10, identity: 0.697

ttaaaaattcttttctattatcatttttattat	CRISPR spacer
tatccaatttttttctatcatcatttttaactc	Protospacer
*    ****.********.********** . .

140. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KY065466 (Streptococcus phage IPP25, complete genome) position: , mismatch: 10, identity: 0.714

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
tagtcacggtttttttcttattttcaatcgtaatt	Protospacer
.  .  * *.*******************  ****

141. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KY065468 (Streptococcus phage IPP27, complete genome) position: , mismatch: 10, identity: 0.714

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
tagtcacggtttttttcttattttcaatcgtaatt	Protospacer
.  .  * *.*******************  ****

142. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045036 (Lactobacillus mali strain LM596 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tgaattttttatttatttttgtatttttttaaaa	Protospacer
.    *********.*********** ****

143. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045036 (Lactobacillus mali strain LM596 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tgaattttttatttatttttgtatttttttaaaa	Protospacer
.    *********.*********** ****

144. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018177 (Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-1, complete sequence) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tgaattttttatttatttttgtatttttttaaaa	Protospacer
.    *********.*********** ****

145. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018181 (Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-1, complete sequence) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tgaattttttatttatttttgtatttttttaaaa	Protospacer
.    *********.*********** ****

146. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN693106 (Marine virus AFVG_25M218, complete genome) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
ttttgtatttatttgtttttgtatttgtcataaa	Protospacer
.***.* *******************.*.

147. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN693116 (Marine virus AFVG_25M217, complete genome) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
ttttgtatttatttgtttttgtatttgtcataaa	Protospacer
.***.* *******************.*.

148. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015330 (Bacillus filamentosus strain Hbe603 plasmid pBEH8, complete sequence) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
tattttttttatttgtttttgttttttctagata	Protospacer
. ** ***************** *** .* . *

149. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053657 (Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
ctccttttttatttctttttgtttttattatcaa	Protospacer
**.. ********* ******* ******  .

150. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MW084976 (Bacillus phage Kirov, complete genome) position: , mismatch: 10, identity: 0.706

ctttatttttatttgtttttgtatttatttattt-----	CRISPR spacer
actattttgtatttgtttttgtattt-----tttgcaaa	Protospacer
 .*  *** *****************     ***

151. spacer 10.102|4241415|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012644 (Rufibacter tibetensis strain 1351 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.706

agcccatgggatggccaacacctgggacgaaatt	CRISPR spacer
gatccatgggatggccaatgcctgggatggcaac	Protospacer
...***************..*******.*. * .

152. spacer 2.42|532323|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_007959 (Nitrobacter hamburgensis X14 plasmid 1, complete sequence) position: , mismatch: 11, identity: 0.676

gtggggggatgaacacctgcttgccgatgccctg	CRISPR spacer
attttccgatgagaacctgcttgccgatgccgaa	Protospacer
.*     *****. *****************  .

153. spacer 10.36|4237035|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032486 (Neokomagataea tanensis strain AH13 = NBRC 106556 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.676

gttattttgttgaattggtttttgatatggcaga	CRISPR spacer
cgcgggcaggtggattggtttttgatattgcaga	Protospacer
  ..  . * **.*************** *****

154. spacer 10.84|4240223|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043057 (Dolichospermum sp. UHCC 0315A plasmid pUHCC0315a, complete sequence) position: , mismatch: 11, identity: 0.686

acgttaactattttattattttcatttaatgtaat	CRISPR spacer
acggtaactatattattattttcatcccgtcgctc	Protospacer
*** ******* *************.. .*    .

155. spacer 10.94|4240887|33|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_019699 (Chroococcidiopsis thermalis PCC 7203 plasmid pCHRO.01, complete sequence) position: , mismatch: 11, identity: 0.667

ttatactccaacaacttttcatattctacttta	CRISPR spacer
actgcttccaacaacttttcatcttctgctagt	Protospacer
 .   .**************** ****.**

156. spacer 10.96|4241018|35|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN855726 (Bacteriophage sp. isolate 241, complete genome) position: , mismatch: 11, identity: 0.686

cttcatctgcttttttcttattttcaatccaaatt	CRISPR spacer
cttcatctgcctttttcttcttttcttcatcatca	Protospacer
**********.******** *****  . . * .

157. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032914 (Alteromonas sp. RKMC-009 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
acagccttttatttgtttttatattgatttggat	Protospacer
 .   .**************.**** ****.  *

158. spacer 10.99|4241218|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to KF929199 (Staphylococcus phage vB_SepS_SEP9, complete genome) position: , mismatch: 11, identity: 0.676

ctttatttttatttgtttttgtatttatttattt	CRISPR spacer
atttatttttatttgttttttaattattccgcca	Protospacer
 *******************  ***  *.....

159. spacer 10.100|4241284|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to NC_015250 (Acinetobacter phage 133, complete genome) position: , mismatch: 11, identity: 0.676

aagtgaagattttgatgggttaattttagcatta	CRISPR spacer
tcctgaagtttttggtgggttaatttttctaaag	Protospacer
   ***** *****.************  .*  .

160. spacer 10.106|4241679|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to AP013413 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C48A-MedDCM-OCT-S28-C15) position: , mismatch: 11, identity: 0.676

aatatgaaaattggtggtagagctttatcaaacg	CRISPR spacer
gctatgaaaatgggtggtggagctttgcagggag	Protospacer
. ********* ******.*******.. ... *

161. spacer 10.106|4241679|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to AP013414 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C48A-MedDCM-OCT-S29-C21) position: , mismatch: 11, identity: 0.676

aatatgaaaattggtggtagagctttatcaaacg	CRISPR spacer
gctatgaaaatgggtggtggagctttgcagggag	Protospacer
. ********* ******.*******.. ... *

162. spacer 10.106|4241679|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to AP013672 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C48A-MedDCM-OCT-S38-C24, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 11, identity: 0.676

aatatgaaaattggtggtagagctttatcaaacg	CRISPR spacer
gctatgaaaatgggtggtggagctttgcagggag	Protospacer
. ********* ******.*******.. ... *

163. spacer 10.106|4241679|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to AP013415 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C48A-MedDCM-OCT-S37-C22) position: , mismatch: 11, identity: 0.676

aatatgaaaattggtggtagagctttatcaaacg	CRISPR spacer
gctatgaaaatgggtggtggagctttgcagggag	Protospacer
. ********* ******.*******.. ... *

164. spacer 10.106|4241679|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to AP013671 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C48A-MedDCM-OCT-S33-C18, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 11, identity: 0.676

aatatgaaaattggtggtagagctttatcaaacg	CRISPR spacer
gctatgaaaatgggtggtggagctttgcagggag	Protospacer
. ********* ******.*******.. ... *

165. spacer 2.2|529703|34|NC_021184|PILER-CR,CRISPRCasFinder,CRT matches to MN586021 (Arthrobacter phage Beagle, complete genome) position: , mismatch: 12, identity: 0.647

ttctagccacagccacggatccaccgcggctttc	CRISPR spacer
cggggtccacagccccggatccacctcggccagg	Protospacer
.   . ******** ********** ****.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

535387 : 545834

RD114_retrovirus(20.0%)

integrase,transposase

attL 531308:531343|attR 550371:550406

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
531308:531343	attL	NA	NA	NA	NA
WP_041285143.1\|535387_536647_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	E0D6V1	RD114_retrovirus	1.6e-08	32.5
WP_015617907.1\|536639_537440_+	AAA family ATPase	NA	NA	NA	NA
WP_083939749.1\|537447_537684_+	DUF5348 domain-containing protein	NA	NA	NA	NA
WP_006524054.1\|538827_538998_+	hypothetical protein	NA	NA	NA	NA
WP_006524053.1\|539074_539830_+	RNA-directed DNA polymerase	A0A0U4J920	Pseudomonas_phage	2.2e-18	31.4
WP_006524052.1\|540009_540891_+\|integrase	site-specific integrase	S5W9T9	Leptospira_phage	1.1e-37	34.3
WP_006524051.1\|540883_542011_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_006521022.1\|542552_543770_-\|transposase	IS256-like element ISDgi1 family transposase	A0A218MNI5	uncultured_virus	2.8e-55	52.3
WP_006524050.1\|543859_544873_-\|integrase	site-specific integrase	A0A1D6X8B0	Bacillus_phage	1.8e-10	22.8
WP_006524049.1\|544859_545834_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
550371:550406	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1043134 : 1094160

Hokovirus(21.43%)

protease,coat,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006521214.1\|1043134_1045864_+	pyruvate, phosphate dikinase	A0A1V0SGR7	Hokovirus	1.6e-34	33.3
WP_015617918.1\|1046360_1046789_+\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	4.6e-29	44.0
WP_015617919.1\|1046775_1048089_+\|transposase	transposase	S4VZ68	Pandoravirus	2.9e-05	23.8
WP_157872726.1\|1048425_1048644_+	hypothetical protein	NA	NA	NA	NA
WP_083939764.1\|1048667_1049027_+	hypothetical protein	NA	NA	NA	NA
WP_041284775.1\|1049031_1049253_+	hypothetical protein	NA	NA	NA	NA
WP_041284776.1\|1049550_1049796_+	hypothetical protein	A0A0A8WF72	Clostridium_phage	3.2e-19	50.6
WP_006521219.1\|1049797_1050184_+\|protease	aspartyl protease family protein	A0A0A8WIU2	Clostridium_phage	4.6e-28	51.6
WP_157872879.1\|1050559_1051723_-	PDZ domain-containing protein	A0A0R6PIZ1	Moraxella_phage	3.7e-20	27.7
WP_006521221.1\|1052579_1053335_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_157872727.1\|1053492_1053657_-	hypothetical protein	NA	NA	NA	NA
WP_006521224.1\|1054586_1055441_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006521225.1\|1055522_1056890_+	MATE family efflux transporter	NA	NA	NA	NA
WP_006521226.1\|1057624_1060786_+	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	3.2e-183	35.1
WP_006521227.1\|1060797_1061586_+	DUF72 domain-containing protein	A0A2K9L3D5	Tupanvirus	7.0e-07	25.3
WP_041284778.1\|1061603_1062167_+	uracil-DNA glycosylase	A0A127AW33	Bacillus_phage	1.3e-15	33.3
WP_157872880.1\|1062743_1063025_-	hypothetical protein	NA	NA	NA	NA
WP_006521229.1\|1063106_1063991_-	hypothetical protein	NA	NA	NA	NA
WP_006521230.1\|1064267_1065443_-	PD40 domain-containing protein	NA	NA	NA	NA
WP_006521233.1\|1066484_1066664_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_041285218.1\|1066656_1067349_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.2e-36	35.9
WP_006521235.1\|1067352_1068276_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.4e-22	27.1
WP_006521236.1\|1068402_1069326_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.3e-41	43.8
WP_041284780.1\|1069309_1070113_+	ABC transporter permease	NA	NA	NA	NA
WP_006521238.1\|1070128_1070953_+	ABC transporter permease	NA	NA	NA	NA
WP_169406849.1\|1070973_1071411_+	hypothetical protein	NA	NA	NA	NA
WP_006521240.1\|1071426_1071690_+	hypothetical protein	NA	NA	NA	NA
WP_041284781.1\|1071880_1072339_+	hypothetical protein	NA	NA	NA	NA
WP_157872728.1\|1072338_1072584_+	hypothetical protein	NA	NA	NA	NA
WP_006521243.1\|1072996_1073248_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_006521244.1\|1073249_1073663_+	PIN domain-containing protein	NA	NA	NA	NA
WP_006521245.1\|1073835_1074117_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_006521246.1\|1074113_1074290_-	hypothetical protein	NA	NA	NA	NA
WP_006521247.1\|1074859_1075831_+	biotin synthase BioB	NA	NA	NA	NA
WP_006521248.1\|1075823_1076507_+	dethiobiotin synthase	NA	NA	NA	NA
WP_157872881.1\|1078112_1078196_-	hypothetical protein	NA	NA	NA	NA
WP_006521252.1\|1079012_1079837_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_157872729.1\|1079929_1080607_+	hypothetical protein	NA	NA	NA	NA
WP_006521254.1\|1080622_1081597_+	DUF4868 domain-containing protein	NA	NA	NA	NA
WP_006521256.1\|1081878_1082244_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_006521257.1\|1082375_1083893_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_006521260.1\|1085094_1085964_+	hypothetical protein	NA	NA	NA	NA
WP_006521261.1\|1086023_1086593_+	flavodoxin family protein	NA	NA	NA	NA
WP_006521262.1\|1086928_1087912_+	DUF3231 family protein	NA	NA	NA	NA
WP_041284783.1\|1087937_1088342_-	EAL domain-containing protein	NA	NA	NA	NA
WP_006521264.1\|1088390_1091096_+	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	8.8e-41	35.3
WP_006521265.1\|1091198_1093844_+	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	4.5e-42	33.4
WP_006521266.1\|1093962_1094160_-\|coat	spore coat protein	NA	NA	NA	NA

DBSCAN-SWA_3

2532402 : 2543603

Prochlorococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006521630.1\|2532402_2533944_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.0e-65	47.4
WP_006521631.1\|2534169_2534781_-	phosphoribosylglycinamide formyltransferase	Q58MV3	Prochlorococcus_phage	2.4e-18	32.2
WP_041285419.1\|2534822_2535890_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	8.1e-75	46.6
WP_041285420.1\|2535916_2537332_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.6e-57	34.6
WP_006521634.1\|2537390_2538095_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HWF9	Synechococcus_phage	5.8e-37	38.7
WP_006521635.1\|2538249_2539545_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.9e-17	32.7
WP_006521636.1\|2539541_2540075_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	9.8e-21	42.6
WP_006521637.1\|2540750_2540966_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006521638.1\|2540985_2541186_+	hypothetical protein	NA	NA	NA	NA
WP_006521639.1\|2541182_2541932_+	Fic family protein	NA	NA	NA	NA
WP_006521640.1\|2542061_2543603_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.7e-20	31.2

DBSCAN-SWA_4

3472461 : 3500191

Erysipelothrix_phage(28.57%)

integrase,transposase

attL 3485151:3485171|attR 3503197:3503217

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157872713.1\|3472461_3473862_+\|transposase	transposase	NA	NA	NA	NA
WP_006524602.1\|3473749_3474352_-	hypothetical protein	NA	NA	NA	NA
WP_006524603.1\|3474338_3474692_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006524604.1\|3475555_3476503_+	hypothetical protein	NA	NA	NA	NA
WP_157872802.1\|3476523_3476736_-	hypothetical protein	NA	NA	NA	NA
WP_157872803.1\|3476734_3477451_+	hypothetical protein	NA	NA	NA	NA
WP_041284949.1\|3477460_3477652_-	hypothetical protein	NA	NA	NA	NA
WP_006524607.1\|3478239_3478812_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	1.3e-10	33.7
WP_006524608.1\|3478990_3479614_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_006524609.1\|3479626_3480361_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.5e-23	30.0
WP_006524610.1\|3480353_3481511_+	hypothetical protein	NA	NA	NA	NA
WP_006524611.1\|3481507_3481942_+	hypothetical protein	NA	NA	NA	NA
WP_157872962.1\|3482165_3482333_-	hypothetical protein	A0A2K5B251	Erysipelothrix_phage	1.3e-08	57.8
WP_006524612.1\|3482404_3482722_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_041284950.1\|3482705_3482993_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_006524614.1\|3483393_3483996_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_041285625.1\|3484336_3485098_-\|transposase	transposase	NA	NA	NA	NA
3485151:3485171	attL	NA	NA	NA	NA
WP_015617995.1\|3485473_3485860_-	hypothetical protein	NA	NA	NA	NA
WP_083940038.1\|3486622_3488143_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	1.7e-09	28.6
WP_006524340.1\|3488534_3488855_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006524339.1\|3488860_3489472_+	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_006524338.1\|3489476_3490703_+	erythromycin esterase family protein	NA	NA	NA	NA
WP_006520307.1\|3490911_3492129_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.3e-55	52.8
WP_006524337.1\|3492630_3493995_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	7.0e-71	35.6
WP_006524336.1\|3494367_3495066_+	TVP38/TMEM64 family protein	NA	NA	NA	NA
WP_041285626.1\|3495225_3496410_-	DUF362 domain-containing protein	NA	NA	NA	NA
WP_006524334.1\|3496513_3496807_-	hypothetical protein	NA	NA	NA	NA
WP_157872964.1\|3497035_3497659_-	DNA/RNA nuclease SfsA	NA	NA	NA	NA
WP_006524332.1\|3498188_3499334_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_006524331.1\|3499330_3500191_-\|integrase	tyrosine-type recombinase/integrase	S5W9T9	Leptospira_phage	9.3e-29	33.9
3503197:3503217	attR	NA	NA	NA	NA

DBSCAN-SWA_5

4461467 : 4560757

uncultured_Caudovirales_phage(13.64%)

integrase,terminase,protease,capsid,tail,holin,portal,transposase,head

attL 4523939:4523998|attR 4562180:4562241

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006521334.1\|4461467_4462346_-\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	2.6e-26	29.2
WP_006521333.1\|4462408_4463341_+\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	1.6e-26	30.4
WP_083939990.1\|4463599_4463749_-	DUF2283 domain-containing protein	NA	NA	NA	NA
WP_006521332.1\|4463859_4464045_-	hypothetical protein	NA	NA	NA	NA
WP_083939991.1\|4464337_4464634_+	hypothetical protein	A0A0C5AMZ5	Paenibacillus_phage	3.3e-10	48.3
WP_006521331.1\|4464704_4465562_+\|integrase	tyrosine-type recombinase/integrase	S5M9V8	Brevibacillus_phage	1.4e-13	24.6
WP_006521330.1\|4465577_4466336_+	hypothetical protein	NA	NA	NA	NA
WP_006521329.1\|4466412_4467399_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	7.7e-19	30.4
WP_006521328.1\|4467521_4470317_+	hypothetical protein	NA	NA	NA	NA
WP_041285023.1\|4471022_4471223_-	helix-turn-helix domain-containing protein	A0A1B1IUF9	uncultured_Mediterranean_phage	6.9e-12	50.0
WP_041285024.1\|4471242_4473015_-	AAA family ATPase	NA	NA	NA	NA
WP_006521325.1\|4473007_4473463_-	hypothetical protein	NA	NA	NA	NA
WP_006521324.1\|4473455_4474466_-	hypothetical protein	NA	NA	NA	NA
WP_006521323.1\|4474819_4475086_+	hypothetical protein	NA	NA	NA	NA
WP_006521322.1\|4475311_4475857_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_006521321.1\|4475972_4476248_+	hypothetical protein	NA	NA	NA	NA
WP_006521320.1\|4476301_4477498_+	DEAD/DEAH box helicase	A0A2H4J064	uncultured_Caudovirales_phage	7.1e-144	63.6
WP_015618021.1\|4477503_4477872_+	VRR-NUC domain-containing protein	A0A2H4J095	uncultured_Caudovirales_phage	1.5e-23	48.9
WP_006521319.1\|4477793_4479494_+	AAA family ATPase	A0A1B1P7N0	Bacillus_phage	1.8e-132	50.0
WP_006521318.1\|4479515_4479968_+	DUF669 domain-containing protein	A0A1B1P7N3	Bacillus_phage	7.3e-25	41.0
WP_041285769.1\|4479972_4481664_+	DNA polymerase	A0A2H4J041	uncultured_Caudovirales_phage	5.3e-185	53.4
WP_083940043.1\|4481663_4482314_+	hypothetical protein	A0A1S5S8E1	Streptococcus_phage	3.6e-33	66.7
WP_006521315.1\|4482601_4484512_+	primase	A0A2H4J1M0	uncultured_Caudovirales_phage	1.4e-181	50.1
WP_006521314.1\|4484712_4485057_+	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	6.5e-26	47.7
WP_006521313.1\|4485046_4485271_+	hypothetical protein	NA	NA	NA	NA
WP_006521311.1\|4485800_4486007_+	hypothetical protein	NA	NA	NA	NA
WP_015618022.1\|4486283_4486667_+	HNH endonuclease	A0A1X9I6D0	Streptococcus_phage	1.3e-22	42.5
WP_006521309.1\|4486709_4486982_-	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_006521308.1\|4486968_4487244_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_006521307.1\|4487504_4488899_+	DNA modification methylase	D0R0C5	Streptococcus_phage	5.7e-52	32.6
WP_015618023.1\|4488902_4490126_+	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	5.0e-137	57.5
WP_006524197.1\|4490194_4490959_+	hypothetical protein	NA	NA	NA	NA
WP_006524198.1\|4490959_4491148_+	hypothetical protein	A0A127AWS3	Bacillus_phage	1.7e-07	52.5
WP_006524199.1\|4491286_4492195_+	amidoligase family protein	A0A1B1IUD7	uncultured_Mediterranean_phage	5.0e-65	46.5
WP_006524200.1\|4492255_4492594_+	hypothetical protein	NA	NA	NA	NA
WP_006524788.1\|4493439_4493913_+\|terminase	phage terminase small subunit P27 family	A0A1B0RXI5	Streptococcus_phage	2.6e-57	69.9
WP_041285027.1\|4493935_4495498_+\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.9e-197	63.6
WP_006524757.1\|4495567_4495879_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_006524758.1\|4495868_4496198_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_083940044.1\|4496279_4497509_+\|portal	phage portal protein	Q6DMU2	Streptococcus_phage	3.9e-145	61.8
WP_006524760.1\|4497501_4498215_+\|protease	Clp protease ClpP	E4ZFM4	Streptococcus_phage	3.3e-64	53.4
WP_006524762.1\|4499865_4501686_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.9e-31	27.9
WP_169406868.1\|4501704_4502046_+\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	6.7e-31	71.7
WP_006524210.1\|4502056_4502743_+	FIVAR domain-containing protein	A0A2K5B289	Erysipelothrix_phage	1.8e-06	45.1
WP_006524211.1\|4502764_4503067_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_006524212.1\|4503066_4503399_+\|head	phage head closure protein	A0A0A7RUH8	Clostridium_phage	2.9e-23	51.9
WP_006524213.1\|4503391_4503763_+	HK97 gp10 family phage protein	A0A288WGM7	Bacillus_phage	4.4e-12	34.5
WP_006524214.1\|4503759_4504086_+	hypothetical protein	A0A2I7SC10	Paenibacillus_phage	1.7e-15	36.9
WP_006524521.1\|4504086_4504653_+\|tail	tail protein	E2ELJ1	Clostridium_phage	1.8e-33	47.0
WP_006524520.1\|4504657_4504957_+	hypothetical protein	A0A2H4JBA8	uncultured_Caudovirales_phage	7.0e-08	29.7
WP_006524519.1\|4504968_4505124_+	hypothetical protein	NA	NA	NA	NA
WP_006524518.1\|4505208_4505475_+	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_006524517.1\|4505461_4505782_+	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	NA	NA	NA	NA
WP_006524516.1\|4505832_4509261_+\|tail	phage tail tape measure protein	A0A0A7S163	Clostridium_phage	1.2e-98	49.9
WP_006524515.1\|4509271_4510123_+\|tail	phage tail family protein	A0A0K2CZA8	Paenibacillus_phage	2.8e-70	48.4
WP_006524514.1\|4510137_4511208_+	hypothetical protein	A0A0C5ABC3	Paenibacillus_phage	1.7e-64	59.7
WP_006524513.1\|4511209_4512007_+	hypothetical protein	E5DV66	Deep-sea_thermophilic_phage	7.1e-15	45.1
WP_006524512.1\|4511999_4513862_+	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_006524511.1\|4513876_4514155_+	hypothetical protein	NA	NA	NA	NA
WP_006524510.1\|4514154_4514295_+	hypothetical protein	NA	NA	NA	NA
WP_006524509.1\|4514368_4515079_+	hypothetical protein	NA	NA	NA	NA
WP_006524508.1\|4515105_4516203_+	hypothetical protein	A0A0K2CZQ1	Paenibacillus_phage	1.3e-83	42.3
WP_006524507.1\|4516250_4516661_+\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	3.4e-37	56.5
WP_006524506.1\|4516653_4517340_+	N-acetylmuramoyl-L-alanine amidase	A0A2H4JCM7	uncultured_Caudovirales_phage	2.3e-30	40.3
WP_006524505.1\|4517471_4518329_+\|integrase	tyrosine-type recombinase/integrase	S5M9V8	Brevibacillus_phage	1.8e-11	23.2
WP_006524504.1\|4518343_4519129_+	hypothetical protein	NA	NA	NA	NA
WP_006524503.1\|4519200_4519467_+	DUF4160 domain-containing protein	NA	NA	NA	NA
WP_006524231.1\|4519479_4519719_+	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_157872838.1\|4519846_4522528_+	Ig-like domain-containing protein	NA	NA	NA	NA
4523939:4523998	attL	NA	NA	NA	NA
WP_157872839.1\|4524086_4524332_-	hypothetical protein	NA	NA	NA	NA
WP_083939992.1\|4525227_4526037_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_006524500.1\|4526026_4526908_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_006524499.1\|4527763_4528789_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_041285030.1\|4528843_4529284_+	hypothetical protein	NA	NA	NA	NA
WP_006524497.1\|4529321_4530362_+	hypothetical protein	NA	NA	NA	NA
WP_006524496.1\|4530693_4531188_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_006524493.1\|4532292_4533261_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	9.8e-19	29.7
WP_006524492.1\|4533974_4534424_+	S-layer protein	NA	NA	NA	NA
WP_006524491.1\|4534552_4534708_+	hypothetical protein	NA	NA	NA	NA
WP_006524490.1\|4534912_4537213_+	peptidase C11	NA	NA	NA	NA
WP_006524489.1\|4537480_4538908_+	YbhB/YbcL family Raf kinase inhibitor-like protein	A0A1P8BL30	Lactococcus_phage	1.1e-07	50.0
WP_006524487.1\|4539648_4541166_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_015618025.1\|4541237_4544585_+	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	5.4e-40	38.4
WP_006524485.1\|4544686_4545418_+	copper amine oxidase N-terminal domain-containing protein	NA	NA	NA	NA
WP_006524484.1\|4545646_4546531_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_006524482.1\|4547579_4548167_-\|transposase	transposase	NA	NA	NA	NA
WP_006524481.1\|4548725_4549019_-	virulence factor	NA	NA	NA	NA
WP_006524480.1\|4549484_4549853_-	hypothetical protein	NA	NA	NA	NA
WP_157872840.1\|4549889_4550897_-	hypothetical protein	NA	NA	NA	NA
WP_006520600.1\|4551095_4551407_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_006520599.1\|4551400_4551760_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.2e-19	47.1
WP_041285577.1\|4551826_4553392_+\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	3.3e-72	36.6
WP_006524246.1\|4554473_4554899_-	HNH endonuclease	NA	NA	NA	NA
WP_157872841.1\|4555440_4555641_-	DUF5348 domain-containing protein	NA	NA	NA	NA
WP_157872842.1\|4557209_4557725_+\|transposase	Mu transposase C-terminal domain-containing protein	NA	NA	NA	NA
WP_006524239.1\|4559179_4560757_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
4562180:4562241	attR	NA	NA	NA	NA

DBSCAN-SWA_6

4571593 : 4598529

Erysipelothrix_phage(20.83%)

integrase,protease,terminase,capsid,tail,holin,portal,head

attL 4567841:4567854|attR 4573534:4573547

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4567841:4567854	attL	NA	NA	NA	NA
WP_006524228.1\|4571593_4572451_-\|integrase	tyrosine-type recombinase/integrase	S5M9V8	Brevibacillus_phage	7.1e-13	24.6
WP_041285790.1\|4572600_4573254_-	N-acetylmuramoyl-L-alanine amidase	A0A1L6BY22	Clostridium_phage	1.5e-31	48.1
WP_006524226.1\|4573240_4573663_-\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	8.3e-39	59.3
4573534:4573547	attR	NA	NA	NA	NA
WP_006524225.1\|4573710_4574808_-	hypothetical protein	A0A0K2CZQ1	Paenibacillus_phage	1.3e-80	41.3
WP_006524224.1\|4574831_4574972_-	hypothetical protein	S6B9W8	Thermus_phage	1.2e-05	61.4
WP_006524223.1\|4574971_4575250_-	hypothetical protein	NA	NA	NA	NA
WP_006524222.1\|4575264_4577127_-	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_006524221.1\|4577119_4577917_-	hypothetical protein	E5DV66	Deep-sea_thermophilic_phage	1.9e-15	47.1
WP_006524220.1\|4577918_4578995_-	hypothetical protein	A0A0C5ABC3	Paenibacillus_phage	7.5e-60	59.2
WP_006524219.1\|4579009_4579861_-\|tail	phage tail family protein	A0A0K2CZA8	Paenibacillus_phage	2.1e-65	46.4
WP_006524218.1\|4579872_4583292_-\|tail	phage tail tape measure protein	A0A2I7SBZ5	Paenibacillus_phage	1.3e-57	34.5
WP_006524217.1\|4583329_4583485_-	hypothetical protein	NA	NA	NA	NA
WP_006524216.1\|4583496_4583790_-	hypothetical protein	H0USX2	Bacillus_phage	8.1e-09	32.6
WP_006524215.1\|4583793_4584600_-	FIVAR domain-containing protein	E2ELJ1	Clostridium_phage	2.0e-33	44.9
WP_006524214.1\|4584600_4584927_-	hypothetical protein	A0A2I7SC10	Paenibacillus_phage	1.7e-15	36.9
WP_006524213.1\|4584923_4585295_-	HK97 gp10 family phage protein	A0A288WGM7	Bacillus_phage	4.4e-12	34.5
WP_015618030.1\|4585287_4585620_-\|head	phage head closure protein	A0A0A7RUH8	Clostridium_phage	2.0e-24	52.8
WP_015618031.1\|4585619_4585922_-\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_006524210.1\|4585943_4586630_-	FIVAR domain-containing protein	A0A2K5B289	Erysipelothrix_phage	1.8e-06	45.1
WP_006524209.1\|4586640_4587825_-\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	3.8e-150	70.0
WP_006524208.1\|4587831_4588530_-\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	1.9e-64	54.5
WP_052544049.1\|4588522_4589758_-\|portal	phage portal protein	Q6DMU2	Streptococcus_phage	1.3e-148	62.3
WP_006524206.1\|4589827_4590154_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_006524205.1\|4590143_4590455_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_041285033.1\|4590524_4592087_-\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	3.1e-200	64.1
WP_006524203.1\|4592109_4592583_-\|terminase	phage terminase small subunit P27 family	A0A1B0RXI5	Streptococcus_phage	2.6e-57	69.9
WP_006524791.1\|4593439_4593778_-	hypothetical protein	NA	NA	NA	NA
WP_006524792.1\|4593838_4594747_-	amidoligase family protein	A0A1B1IUD7	uncultured_Mediterranean_phage	1.7e-65	46.5
WP_006524198.1\|4594885_4595074_-	hypothetical protein	A0A127AWS3	Bacillus_phage	1.7e-07	52.5
WP_006524793.1\|4595074_4595839_-	hypothetical protein	NA	NA	NA	NA
WP_015618032.1\|4595907_4597131_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	2.1e-135	57.2
WP_006524195.1\|4597134_4598529_-	DNA modification methylase	D0R0C5	Streptococcus_phage	4.7e-54	33.0

DBSCAN-SWA_7

4602183 : 4615015

Erysipelothrix_phage(54.55%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006524189.1\|4602183_4603536_-	DEAD/DEAH box helicase	A0A2K5B273	Erysipelothrix_phage	1.2e-160	71.0
WP_006524188.1\|4603516_4603798_-	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	3.8e-24	63.3
WP_006524187.1\|4603950_4606197_-	primase C-terminal domain-containing protein	A0A1X9I6B6	Streptococcus_phage	3.8e-207	49.3
WP_006524186.1\|4606224_4606872_-	antA/AntB antirepressor family protein	A0A2H4IZX7	uncultured_Caudovirales_phage	1.7e-27	51.5
WP_006524185.1\|4606859_4607267_-	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	2.6e-37	53.3
WP_006524184.1\|4607212_4607470_-	hypothetical protein	A0A2K5B269	Erysipelothrix_phage	2.4e-17	59.4
WP_006524183.1\|4607721_4610022_-	hypothetical protein	A0A2K5B2B0	Erysipelothrix_phage	1.9e-246	56.5
WP_006524182.1\|4610080_4610638_-	DUF2815 family protein	E4ZFK3	Streptococcus_phage	6.1e-74	75.4
WP_006524181.1\|4610651_4611773_-	DUF2800 domain-containing protein	A0A1X9I6D8	Streptococcus_phage	1.5e-119	56.6
WP_041285797.1\|4611765_4612077_-	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	7.5e-13	42.6
WP_006524179.1\|4612060_4612222_-	hypothetical protein	NA	NA	NA	NA
WP_006524178.1\|4612349_4612847_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_006524177.1\|4613152_4615015_-	helix-turn-helix transcriptional regulator	E4ZFJ9	Streptococcus_phage	1.2e-73	30.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_021184

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection