CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016148	Thermovirga lienii DSM 17291, complete sequence	2 crisprs	WYL,csm6,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,cas1,cas2,cas8b1,cas7,cas5,cas3,cas4,csa3,cas14j,DinG	0	12	3	0
NC_016149	Thermovirga lienii DSM 17291 plasmid pTLIE01, complete sequence	0 crisprs	c2c9_V-U4	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_016148_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016148_1

256316-257821

TypeIII

I-A,II-B,III-A

Consensus_repeat	Method
GATTCAATCGAACCGATACGGAATGGAAAC	PILER-CR
GATTCAATCGAACCGATACGGAATGGAAAC	CRISPRCasFinder
GATTCAATCGAACCGATACGGAATGGAAAC	CRT

23 spacers

cas2,cas1,cas6,csm5gr7,csm4gr5

The CRISPR arrays of NC_016148_1

>merge|NC_016148|1|256316-257821|PILER-CR,CRISPRCasFinder,CRT
GATTCAATCGAACCGATACGGAATGGAAACCGTCCCGTCGCTCACATTGTGGGCACATTACCAGATTCAATCGAACCGATACGGAATGGAAACTGTTTTGGCGCCCGCCACGTTTCGCTATTTGATTCAATCGAACCGATACGGAATGGAAACGTTACGCTCACGATAGGCAAGCTCCAGTATTTGATTCAATCGAACCGATACGGAATGGAAACATATTCTTTCGCCCTCAAACCTCAAAGGGCGGCGATTCAATCGAACCGATACGGAATGGAAACAAATAAACTGAGCTTTGTTTAGAGTTTCTTTGATTCAATCGAACCGATACGGAATGGAAACTAGCGCCGGCATGAAGAAGGGCGCCCCTCCTAGATTCAATCGAACCGATACGGAATGGAAACTGCCTCCAACATCTCATATCACTCCTTTTTGTTATGATTCAATCGAACCGATACGGAATGGAAACTTTCTGTTAACTGTCTAGCCCTGACGAAGACCTCTTCGATTCAATCGAACCGATACGGAATGGAAACGTCGCTATCGGATATATTCTTAATTTATCATACGGATTCAATCGAACCGATACGGAATGGAAACTGTGTCAAGCTCTAATGGTAAAGTCTAAATATTCGATTCAATCGAACCGATACGGAATGGAAACCAGTAAACGTCCCAGCCGTCCTCACGTAGCCACTTGAGATTCAATCGAACCGATACGGAATGGAAACAACATTTGGTGCAAGGCGTCATCGATGTCGTTAAGGATTCAATCGAACCGATACGGAATGGAAACACCTTTCCAAATATTATATTTTATTGTCAAGGATTCAATCGAACCGATACGGAATGGAAACTTCAGCGCTGCAAACGGAAGGATATAGGAGACAGATTCAATCGAACCGATACGGAATGGAAACCAATATCCAACCTTTTCATCGCTTATGCGGACAGGATTCAATCGAACCGATACGGAATGGAAACGCATCCCATCCTTTCCTTTCTTATTGTCAAGGTACGATGATTCAATCGAACCGATACGGAATGGAAACGTGCACTCCTCCGTACCATTTAGATAGTACGGAGCATAGATTCAATCGAACCGATACGGAATGGAAACCTGAAAATATTTTTTCAGCGCTGAATATGGGAGAATGGATTCAATCGAACCGATACGGAATGGAAACCCTGATTTGTTCCTGATCCAACTGTGGTAATTGGATTCAATCGAACCGATACGGAATGGAAACTACTACACCCCATCCTTTCTTATATTTTCTTGTCGATTCAATCGAACCGATACGGAATGGAAACTCGCGCCGATCGGGAGGCGTTGTGAAAAAGAGGAGCCCGATTCAATCGAACCGATACGGAATGGAAATTGTTCTCTCTGTATTGATATCTCCCTTTGGCGGATTCAATCGAACCGATACGGAATGGAAACCCTTGGACAGCCACCACCTTGCCCACATAGGCAAAGATTCAATCGAACCGATACGGAATGGAAAC

>NC_016148|1|1|256316-257821|PILER-CR
GATTCAATCGAACCGATACGGAATGGAAAC	CGTCCCGTCGCTCACATTGTGGGCACATTACCA
GATTCAATCGAACCGATACGGAATGGAAAC	TGTTTTGGCGCCCGCCACGTTTCGCTATTT
GATTCAATCGAACCGATACGGAATGGAAAC	GTTACGCTCACGATAGGCAAGCTCCAGTATTT
GATTCAATCGAACCGATACGGAATGGAAAC	ATATTCTTTCGCCCTCAAACCTCAAAGGGCGGC
GATTCAATCGAACCGATACGGAATGGAAAC	AAATAAACTGAGCTTTGTTTAGAGTTTCTTT
GATTCAATCGAACCGATACGGAATGGAAAC	TAGCGCCGGCATGAAGAAGGGCGCCCCTCCTA
GATTCAATCGAACCGATACGGAATGGAAAC	TGCCTCCAACATCTCATATCACTCCTTTTTGTTAT
GATTCAATCGAACCGATACGGAATGGAAAC	TTTCTGTTAACTGTCTAGCCCTGACGAAGACCTCTTC
GATTCAATCGAACCGATACGGAATGGAAAC	GTCGCTATCGGATATATTCTTAATTTATCATACG
GATTCAATCGAACCGATACGGAATGGAAAC	TGTGTCAAGCTCTAATGGTAAAGTCTAAATATTC
GATTCAATCGAACCGATACGGAATGGAAAC	CAGTAAACGTCCCAGCCGTCCTCACGTAGCCACTTGA
GATTCAATCGAACCGATACGGAATGGAAAC	AACATTTGGTGCAAGGCGTCATCGATGTCGTTAAG
GATTCAATCGAACCGATACGGAATGGAAAC	ACCTTTCCAAATATTATATTTTATTGTCAAG
GATTCAATCGAACCGATACGGAATGGAAAC	TTCAGCGCTGCAAACGGAAGGATATAGGAGACA
GATTCAATCGAACCGATACGGAATGGAAAC	CAATATCCAACCTTTTCATCGCTTATGCGGACAG
GATTCAATCGAACCGATACGGAATGGAAAC	GCATCCCATCCTTTCCTTTCTTATTGTCAAGGTACGAT
GATTCAATCGAACCGATACGGAATGGAAAC	GTGCACTCCTCCGTACCATTTAGATAGTACGGAGCATA
GATTCAATCGAACCGATACGGAATGGAAAC	CTGAAAATATTTTTTCAGCGCTGAATATGGGAGAATG
GATTCAATCGAACCGATACGGAATGGAAAC	CCTGATTTGTTCCTGATCCAACTGTGGTAATTG
GATTCAATCGAACCGATACGGAATGGAAAC	TACTACACCCCATCCTTTCTTATATTTTCTTGTC
GATTCAATCGAACCGATACGGAATGGAAAC	TCGCGCCGATCGGGAGGCGTTGTGAAAAAGAGGAGCCC
GATTCAATCGAACCGATACGGAATGGAAAT	TGTTCTCTCTGTATTGATATCTCCCTTTGGCG
GATTCAATCGAACCGATACGGAATGGAAAC	CCTTGGACAGCCACCACCTTGCCCACATAGGCAAA
GATTCAATCGAACCGATACGGAATGGAAAC

>NC_016148|1|1|256316-257821|CRISPRCasFinder
GATTCAATCGAACCGATACGGAATGGAAAC	CGTCCCGTCGCTCACATTGTGGGCACATTACCA
GATTCAATCGAACCGATACGGAATGGAAAC	TGTTTTGGCGCCCGCCACGTTTCGCTATTT
GATTCAATCGAACCGATACGGAATGGAAAC	GTTACGCTCACGATAGGCAAGCTCCAGTATTT
GATTCAATCGAACCGATACGGAATGGAAAC	ATATTCTTTCGCCCTCAAACCTCAAAGGGCGGC
GATTCAATCGAACCGATACGGAATGGAAAC	AAATAAACTGAGCTTTGTTTAGAGTTTCTTT
GATTCAATCGAACCGATACGGAATGGAAAC	TAGCGCCGGCATGAAGAAGGGCGCCCCTCCTA
GATTCAATCGAACCGATACGGAATGGAAAC	TGCCTCCAACATCTCATATCACTCCTTTTTGTTAT
GATTCAATCGAACCGATACGGAATGGAAAC	TTTCTGTTAACTGTCTAGCCCTGACGAAGACCTCTTC
GATTCAATCGAACCGATACGGAATGGAAAC	GTCGCTATCGGATATATTCTTAATTTATCATACG
GATTCAATCGAACCGATACGGAATGGAAAC	TGTGTCAAGCTCTAATGGTAAAGTCTAAATATTC
GATTCAATCGAACCGATACGGAATGGAAAC	CAGTAAACGTCCCAGCCGTCCTCACGTAGCCACTTGA
GATTCAATCGAACCGATACGGAATGGAAAC	AACATTTGGTGCAAGGCGTCATCGATGTCGTTAAG
GATTCAATCGAACCGATACGGAATGGAAAC	ACCTTTCCAAATATTATATTTTATTGTCAAG
GATTCAATCGAACCGATACGGAATGGAAAC	TTCAGCGCTGCAAACGGAAGGATATAGGAGACA
GATTCAATCGAACCGATACGGAATGGAAAC	CAATATCCAACCTTTTCATCGCTTATGCGGACAG
GATTCAATCGAACCGATACGGAATGGAAAC	GCATCCCATCCTTTCCTTTCTTATTGTCAAGGTACGAT
GATTCAATCGAACCGATACGGAATGGAAAC	GTGCACTCCTCCGTACCATTTAGATAGTACGGAGCATA
GATTCAATCGAACCGATACGGAATGGAAAC	CTGAAAATATTTTTTCAGCGCTGAATATGGGAGAATG
GATTCAATCGAACCGATACGGAATGGAAAC	CCTGATTTGTTCCTGATCCAACTGTGGTAATTG
GATTCAATCGAACCGATACGGAATGGAAAC	TACTACACCCCATCCTTTCTTATATTTTCTTGTC
GATTCAATCGAACCGATACGGAATGGAAAC	TCGCGCCGATCGGGAGGCGTTGTGAAAAAGAGGAGCCC
GATTCAATCGAACCGATACGGAATGGAAAT	TGTTCTCTCTGTATTGATATCTCCCTTTGGCG
GATTCAATCGAACCGATACGGAATGGAAAC	CCTTGGACAGCCACCACCTTGCCCACATAGGCAAA
GATTCAATCGAACCGATACGGAATGGAAAC

>NC_016148|1|1|256316-257821|CRT
GATTCAATCGAACCGATACGGAATGGAAAC	CGTCCCGTCGCTCACATTGTGGGCACATTACCA
GATTCAATCGAACCGATACGGAATGGAAAC	TGTTTTGGCGCCCGCCACGTTTCGCTATTT
GATTCAATCGAACCGATACGGAATGGAAAC	GTTACGCTCACGATAGGCAAGCTCCAGTATTT
GATTCAATCGAACCGATACGGAATGGAAAC	ATATTCTTTCGCCCTCAAACCTCAAAGGGCGGC
GATTCAATCGAACCGATACGGAATGGAAAC	AAATAAACTGAGCTTTGTTTAGAGTTTCTTT
GATTCAATCGAACCGATACGGAATGGAAAC	TAGCGCCGGCATGAAGAAGGGCGCCCCTCCTA
GATTCAATCGAACCGATACGGAATGGAAAC	TGCCTCCAACATCTCATATCACTCCTTTTTGTTAT
GATTCAATCGAACCGATACGGAATGGAAAC	TTTCTGTTAACTGTCTAGCCCTGACGAAGACCTCTTC
GATTCAATCGAACCGATACGGAATGGAAAC	GTCGCTATCGGATATATTCTTAATTTATCATACG
GATTCAATCGAACCGATACGGAATGGAAAC	TGTGTCAAGCTCTAATGGTAAAGTCTAAATATTC
GATTCAATCGAACCGATACGGAATGGAAAC	CAGTAAACGTCCCAGCCGTCCTCACGTAGCCACTTGA
GATTCAATCGAACCGATACGGAATGGAAAC	AACATTTGGTGCAAGGCGTCATCGATGTCGTTAAG
GATTCAATCGAACCGATACGGAATGGAAAC	ACCTTTCCAAATATTATATTTTATTGTCAAG
GATTCAATCGAACCGATACGGAATGGAAAC	TTCAGCGCTGCAAACGGAAGGATATAGGAGACA
GATTCAATCGAACCGATACGGAATGGAAAC	CAATATCCAACCTTTTCATCGCTTATGCGGACAG
GATTCAATCGAACCGATACGGAATGGAAAC	GCATCCCATCCTTTCCTTTCTTATTGTCAAGGTACGAT
GATTCAATCGAACCGATACGGAATGGAAAC	GTGCACTCCTCCGTACCATTTAGATAGTACGGAGCATA
GATTCAATCGAACCGATACGGAATGGAAAC	CTGAAAATATTTTTTCAGCGCTGAATATGGGAGAATG
GATTCAATCGAACCGATACGGAATGGAAAC	CCTGATTTGTTCCTGATCCAACTGTGGTAATTG
GATTCAATCGAACCGATACGGAATGGAAAC	TACTACACCCCATCCTTTCTTATATTTTCTTGTC
GATTCAATCGAACCGATACGGAATGGAAAC	TCGCGCCGATCGGGAGGCGTTGTGAAAAAGAGGAGCCC
GATTCAATCGAACCGATACGGAATGGAAAT	TGTTCTCTCTGTATTGATATCTCCCTTTGGCG
GATTCAATCGAACCGATACGGAATGGAAAC	CCTTGGACAGCCACCACCTTGCCCACATAGGCAAA
GATTCAATCGAACCGATACGGAATGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016148.1\|WP_014162180.1\|252697_253930_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|307151
NC_016148.1\|WP_014162403.1\|249396_250563_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NC_016148.1\|WP_014162417.1\|261511_262432_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067
NC_016148.1\|WP_014162420.1\|265067_266390_-\|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|215439
NC_016148.1\|WP_014162413.1\|258398_259115_+\|citryl-CoA-lyase	unknown	unknown	gnl\|CDD\|235748
NC_016148.1\|WP_014162414.1\|259459_260113_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_016148.1\|WP_014162411.1\|255933_256221_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_016148.1\|WP_014162419.1\|264137_264905_-\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|235036
NC_016148.1\|WP_014162402.1\|248473_249400_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|187794
NC_016148.1\|WP_014162416.1\|261149_261491_+\|DsrE-family-protein	unknown	unknown	gnl\|CDD\|225905
NC_016148.1\|WP_014162404.1\|250562_251240_+\|hypothetical-protein	unknown	unknown	unknown
NC_016148.1\|WP_014162405.1\|251232_252003_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NC_016148.1\|WP_014162421.1\|266405_266624_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224671
NC_016148.1\|WP_014162409.1\|254790_255648_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_016148.1\|WP_014162408.1\|254305_254794_+\|hypothetical-protein	unknown	unknown	unknown
NC_016148.1\|WP_169311576.1\|252081_252759_+\|hypothetical-protein	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_016148.1\|WP_169311577.1\|262400_263714_-\|sensor-domain-containing-diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NC_016148.1\|WP_014162410.1\|255650_255956_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_016148.1\|WP_014162415.1\|260140_260941_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|234595
NC_016148.1\|WP_014162412.1\|258249_258408_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_016148.1\|WP_014162180.1\|252697_253930_-\|IS256-family-transposase	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	1.67095e-145
NC_016148.1\|WP_014162413.1\|258398_259115_+\|citryl-CoA-lyase	gnl\|CDD\|235748	PRK06224, PRK06224, citryl-CoA lyase.	1.00084e-51
NC_016148.1\|WP_014162403.1\|249396_250563_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.27808e-21
NC_016148.1\|WP_014162420.1\|265067_266390_-\|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein	gnl\|CDD\|215439	PLN02819, PLN02819, lysine-ketoglutarate reductase/saccharopine dehydrogenase.	1.02594e-103
NC_016148.1\|WP_014162414.1\|259459_260113_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.96799e-06
NC_016148.1\|WP_014162411.1\|255933_256221_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.33099e-17
NC_016148.1\|WP_014162419.1\|264137_264905_-\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|235036	PRK02412, aroD, type I 3-dehydroquinate dehydratase.	4.89958e-84
NC_016148.1\|WP_014162402.1\|248473_249400_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|187794	cd09663, Csm4_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.41411e-29
NC_016148.1\|WP_014162410.1\|255650_255956_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.86069e-19
NC_016148.1\|WP_014162405.1\|251232_252003_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.58566e-38
NC_016148.1\|WP_014162421.1\|266405_266624_-\|hypothetical-protein	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	0.0055629
NC_016148.1\|WP_014162409.1\|254790_255648_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.04826e-46
NC_016148.1\|WP_169311576.1\|252081_252759_+\|hypothetical-protein	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	6.57315e-13
NC_016148.1\|WP_169311577.1\|262400_263714_-\|sensor-domain-containing-diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	6.66443e-56
NC_016148.1\|WP_014162416.1\|261149_261491_+\|DsrE-family-protein	gnl\|CDD\|225905	COG3370, COG3370, Uncharacterized protein conserved in archaea [Function unknown].	6.41434e-12
NC_016148.1\|WP_014162415.1\|260140_260941_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|234595	PRK00048, PRK00048, dihydrodipicolinate reductase; Provisional.	1.25644e-44
NC_016148.1\|WP_014162417.1\|261511_262432_+\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	1.46092e-53

>NC_016148.1|WP_014162411.1|255933_256221_+|CRISPR-associated-endonuclease-Cas2
MRNKKEINTFIIYDVGQKRVPKVHKVLCSYMFWEQNSVFSGNISKGMLKKILYKLDVIIDTKCDCVYCYSLRYPYTLQVERWGKYSTRYSEIVRL
>NC_016148.1|WP_014162410.1|255650_255956_+|CRISPR-associated-endonuclease-Cas2
MFRVLVYDVSQKKVYKVRRYLADKMFWVQNSTFEGYLTEEQKLVVMESLGKILDPEEDSIMIFSTESEYAWKKMILGVDKSCISYLLKYGGGEKDEEQEGN
>NC_016148.1|WP_014162409.1|254790_255648_+|CRISPR-associated-endonuclease-Cas1
MNIGEKKQKREITIIQGWRTPYVSMFIPADPVVFPYRVLRLAQAVYYATPEKRIRVIKTLLKGVAESYVFWANICSQCLITEEILRAVRVFRRNIDSIGEVKEGLGFEGNFHKEIFEIWMRNVPPEFGFTGRNRQPPRDPLNALISYGNSLMYKICVPPLQKAGFNTSVGFLHQPGRGRHTLALDIAELLKPVLVEAVIWNMLLEGEFARDMTTEGPGGCFLNKDGKKAYRDSLFKMVEDLFGGSTRCHFGWPINLLKALEETVARISRDLIQETIPESWVVFRR
>NC_016148.1|WP_014162408.1|254305_254794_+|hypothetical-protein
MEIDNLITYGWALWCPIAGQLWDWGIDLKDEESRFVFEKSWFFIDYDKEDLWEHMEINDFAPHVEFYKKFVCIYAAQWPPLHVWIGAALRLLFVVPEMDHGYVVRMNNYQTEKIKVKLNEVIKEKLFSKWEELDHGSFFKRVNKCQFCFLRDLCWFLQEVSI
>NC_016148.1|WP_014162180.1|252697_253930_-|IS256-family-transposase
MAHYQVTVDCDLLQGLFIRDDGLARLVENIVNQILDAQATEQLRAKPYERTEERQGYRNGYRDKLLKSRVGELTLMVPRLRSGHFSTELFERYQRSEQALLLAMVEMVVNGVSTRKVRAVVDELCGTEFSKSTVSSLCKRLDDIVKEWNERDLSSQEYPFLLVDAIVIRVRKGGRVRLSSVLLATGINREGYREILGLMLGDSESEAAWSEFFGRLKERGLKGVDLVVSDDHKGLINAIETHFQGATWQRCQTHFIRNILDACPKSLQGDLHGRLRLIFDAPDMETARRLLNETIEAFGARAPKAVERLEAGFEDAMAVMALPGRYRKRLRTTNGVERLNQEIRRRERVIRIFPNEESAVRLIGAVLVEIDEVWTTGKRYFDMAEYWEWKANTEKQQKEVNNADTQVNVA
>NC_016148.1|WP_169311576.1|252081_252759_+|hypothetical-protein
MKNREKDVGVLVPVLQISEIFALGGACPDNAALSLLAEKAVPLHIFDNKTYEGSWMPYMSILSGQVSMAQYMVLFDKDLTLKIAQEIVRGACRLRCSVARKWFRKDADMWESKYLDCLSKIYTKSAPSEKVIREILELDYERITTYLSDIDWYAFAEGIAKATVVSAFSRLSLDPWINALSIMDPCFGSSPNLCVNSLWQIRSPRFKLHLPGYRHYSPPSAVFLC
>NC_016148.1|WP_014162405.1|251232_252003_+|CRISPR-associated-endoribonuclease-Cas6
MIELRLRVKFKIKPGSTIDFNYQWHITAMVYKVLSVSAPEFSKQLHDSGYPHLAGPDFKFFTFSTLWAGRGATTVVGKRLCFESDSLLWRFDTPVAVVSSLLAEGLMSLGEVRIGSLNAEVGQIIDEPMPDFSDGFATFSCISPLVSSVPDAKLGHKYLDPKDNQFWEVLRGNLIKKWETLYRKPFQGEVKLQPDWEYIKTRKTSKLISLKGRYLIRGHLVPFAVEGAPQIIALGYSAGFGGRNSLGFGMVEVAKG
>NC_016148.1|WP_014162404.1|250562_251240_+|hypothetical-protein
MGKVGSIALYLEVSNQDIWKEHETRASFVHNVFGNYEEGLRAGPRLAARRGYVGLLICAFTPEGYRKMLLNASDIYGKKIDGPWGRVQCVRIRADDSGHPWIRTLDIGKPKYFCMLDGPVRLKTYSPIRSPFSILKDLEASQRFLWEYSGAKDLEFSFDLPHWIFTKVRLKANIKQDVQDVTGSLCVFSSHKMAQLILDFAILRGFGSERERGFGSLDVIVDRGD
>NC_016148.1|WP_014162403.1|249396_250563_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MSENKLPWKIKKYKARFVALSPIHIGTGEVLPACRYVLPPEGQDQGWCLKESFSAGLLAEGRISIKDYMEKPLSLDMPILKRGVDDGNFLYPISFTKAAREKLKKEVKPFVRDGFGRAYLPGSSIKGMLRTALAFSFLMNEEQARKNLLKQLDQLEPKGLIEKMNNVSPKNIKEIRKKNAARVSLVENLFRPLEKEKTDPKYDILRAVKVSDSEPIDTPLVVAAVNIFTSKGSRIEPLSSDTPPTFCEVVDPGTEICFEITLDEGLLVKLGESNPSKIRIKNHYDLLSALQDHARVMVNIEKSFLEKNGVNDVWDKEYEQGEDADYAIVRLGWGSGWTGSSLFPILSCDDPEKETPKRPLSRKIVISSKGEPRAMLGWGKLYIEEIPE
>NC_016148.1|WP_014162402.1|248473_249400_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MLKPLVFHLRFKSGIRQGTLAGDVNRQAGFIGGSTVWGGVGWASAQLNGPEITERLVRTCRLSSLLWKRDDCYYVPAPVFPVAGKGIDDRKKLKKVQWVPVDELNHFVAEKINSNLGDRFFTEETVVSAALDRVSKAAVPYYKRRLKVAEGVVGVLVAECPEDMVAAFKGAIRLLGDTGLGGERSTGWGVFDVEEVSAAETPFGDLLQKEGKRYMTLGAFLPKPEELNLLEKEREYTGYNLWRFRGYVGETDVIKPTVVCLSHGSLLPFKPVGKVIDITPSRMEHPVLFNGCPPSLAVDLPKLEEVEE
>NC_016148.1|WP_014162412.1|258249_258408_+|hypothetical-protein
MEKVLRNVIGEEWVLELKLKKVQKPSKAKHAAVSNERNHNHIEHLGRDGEWW
>NC_016148.1|WP_014162413.1|258398_259115_+|citryl-CoA-lyase
MVVRSSEPTYVAPNRLVLDGEDITSWIERASPAELWFRMIQGRAPQPVEVRVFNAILCAMADHGSTPPSTQAARLVASTGSGVHCALAAGMMAFGEHHAGAIEKAMGFFEEINQSGRKPSEVVMEILAERRKIPGFGHRYHTKDPRVEPLVRLGKNLPNTTFLEMFLEMERALRNLKGINGNIDGVSGALLLDMGFVKEAGRAVFFAGRLPGMVSWIIKEIYSGYFKPYKLCLDAKGA
>NC_016148.1|WP_014162414.1|259459_260113_+|GNAT-family-N-acetyltransferase
MLENVVLTSKKTRKKPLLDDRKIPQKEQITVHKAEVEDVEQIYRVACSVGTALKDPYKGFLIDDYLSDPDYYKEMFAKAAQELDHFYVAKKNDAVVGFLMAYPKEKLLEVDPLWLEEIVWDPDFDHESKTKNFALVGKTAIHANLTGKGIGSSLYARLIRDLKAQGIEDLFGETVISPTPNFASLAFRIKQKYSLAGIRYVNYKGRRVTDLIYHRHI
>NC_016148.1|WP_014162415.1|260140_260941_-|4-hydroxy-tetrahydrodipicolinate-reductase
MIKIFLAGASGNVGKAIIRAIQTTEKDSFSLVGGWCKEQDEDLGILAGVGPLGIKVSESLEEGLVNSKPDMVIDFTSTVILEDNMKLYLKHGLDAVIGTTGLTEEQLEPYKNEVVKKGLRWAAIPNYGLGIYLVTKFIREARKFFPFVSIIDKHTNKMANAPSGTAAALAKAASEGKMGEIESKETYPGVLGGKIEGVQVLSQRLPWPGPYSGHEITLARKDEIIKISVEDYTSDIYMDGVFLTARKIKESPRGVFYRSLEEVMEK
>NC_016148.1|WP_014162416.1|261149_261491_+|DsrE-family-protein
MGNGHLYILWTSGDPVTAEKMVFMYAINSLKKKWWDKVTLVVWGAAAQLAGQDAKIQKKLKEAQKVGVHVAACKACADQLGVTEVLENLGVEVIYWGGPLTEVLKKGEKLLTI
>NC_016148.1|WP_014162417.1|261511_262432_+|EamA-family-transporter
MSEVNPEKRFPNWLIVLMFAGLYTTWSTTYLAIYYMVKTIPPYLSSGLRFLVAGAILYGFARIKNKNERISLKHWKSALITGGLVIWLGNGSVVWGEKYISSSLAALLIATVPLWIVLLNWLLFGGGKPGVIEMVGVVLGFLGVALLIVFTRHIGGEGYNLKGIVIVLAASISWATGSLYSRYSQTPSSPLLSVAAQMLAGGALMFLASFFVGEWATFELSKVSMVSVLSWAYLVVFGSLVGFVCYMTLMKVCRPSKVATYAYVTPVGAVFLGWLIAGDTITYHTLIAGGIIILAVLMIISFAPKE
>NC_016148.1|WP_169311577.1|262400_263714_-|sensor-domain-containing-diguanylate-cyclase
MKFLKSETMDELADVFADALRKLGHKNFYLELEEFPSQDTNAYCPGTETNRTCFPISCEGTNWGFLKFKGSLPKSDQEVINLLCSYFAASRTKLWQKEAIERKSRMGQIIFDIVCNAAKEKGIHDICRKVVQEMSRNTSLPWIDIWEVIDEKTGKTRLVYKSGDASREVIAKVESGKGLVGKAVRKKRTLYFPDVTKYPENIQVSTESRSELDVPIIFDEGVLGVLSIGSPKINGFKDEEIELIEILAMHLGVLWAHQNLLEQTKLEALKDPLTGLWNRKFFSDRLQEELSRCKRYNTTFSLVIMDLAGFKHINDTLGHLEGDNILIEFSKFMEQRIRRSDILARYGGDEFIAILPDTNKTEALKLSFRLKREVKEAFQKELEIPLDVDFGVASFPEDSSDGHKLINTADERLYDAKRKAKLLKKEALTPSVQRILS
>NC_016148.1|WP_014162419.1|264137_264905_-|type-I-3-dehydroquinate-dehydratase
MRPTPLHPIKTRGKTLGAPKPLVCISLIDSQELIICEEAKRTIQLAPDIIELRIDAWDFIEDVETSLSTIKEVRKIVKDVPIILTCRGHWEGGFKEVSDEAKFSLYEKAVKLKLVDYIDIELAYGEEKIQKAKELLKGTSTYLIVSFHDFEKTPPEEELYSIMASEIKAGAHVAKLAVMPKKEEDVLALLAATLSTRRDFPEVPLITMSMGELGSLSRVIGGKFGSDLTFAVGNKESAPGQIPVTKLKQCLDALF
>NC_016148.1|WP_014162420.1|265067_266390_-|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein
MAQILILGAGRVARPCVQYLLRNTEHSVTVVDIDENNLKRATGGHPRSQIIVGDAANETERFIEQVKPHIVINLLPAQFMPPVAKKCVEFGINYVDPSYIKDEMRSLDAAAKEKGVLILCELGLDPGIDHMSAAKTIKEIHEKGGLVDSFWSCCGALPSLCDNNNPLGYKLSWSPEALIGASKRTARFLRNGEVVVLPDGETYKHPSLVDVEGLGCFEEYANADSIPYIELYGIKEAKHVYRGTFRYPGWCELIAKMNDLGLFETTEMDLKELTYRDFMAKILNTGKANVEEKLCSALGREAFSSVFLKLKWLGLLSEEKIPFETGSPRSVVASLFHKRLVFSKGEKDLVLMEHRYVASFPKENTKKLITSTLICTGSVDEDTAIAKTTGIPPAIGAMLILQGKIKATGVHAPVLPEIYEPSLKLLEKEGITFTEKETTI
>NC_016148.1|WP_014162421.1|266405_266624_-|hypothetical-protein
MEHYGFLSLLPPIIAVLLAVRYRNVIVALFSGVLIGALVLANWNPIAALSMTIKDYIFKQASGGYNSSLLVM

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Crispr_ID: NC_016148_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016148_2

279012-282019

TypeI-B

Consensus_repeat	Method
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CRISPRCasFinder
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CRT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	PILER-CR

45 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b1,cas6

The CRISPR arrays of NC_016148_2

>merge|NC_016148|2|279012-282019|CRISPRCasFinder,CRT,PILER-CR
GTTTTAGACCTTCCTATAAGGGATGGAAACACTATGGCTTTGGCTCTTTTATTATAGCCATTATCTGGTTTTAGACCTTCCTATAAGGGATGGAAACACTACATTGGCAATTTCTTTTGCTGACTTATTTTTAGTTTTAGACCTTCCTATAAGGGATGGAAACGGTTTTTCAACAACTGCAGCTTGGGGCTCTAAACCAAGTTTTAGACCTTCCTATAAGGGATGGAAACGGGGCTTTAGGCGCATCCTCCTGGCCCGTGTCACCGTGTTTTAGACCTTCCTATAAGGGATGGAAACTCGAACTGTTCCTCAAGCCCCCTTGTGCTGAGCCACGTTTTAGACCTTCCTATAAGGGATGGAAACGAGCGGTGACGGTGCCAGCTAGCGGGACCACAGCCAGTTTTAGACCTTCCTATAAGGGATGGAAACTATGTCAGCGCCATATGTCGAGGATATGCATTTTGGTTTTAGACCTTCCTATAAGGGATGGAAACACGACATAGATGCACTGCTTCAGGAGCTCTTCGATGGTTTTAGACCTTCCTATAAGGGATGGAAACATGAAAATGACATAACCAGATACAAATGAAGGCGGGTTTTAGACCTTCCTATAAGGGATGGAAACTAGACTTCATGCGCGACGACTTCAGTCGTCTGCCCCGTTTTAGACCTTCCTATAAGGGATGGAAACTAGCAATAAGAGAAAGGAGTGAAAAACATGACTCTAGTTTTAGACCTTCCTATAAGGGATGGAAACATGCCGTGCGGGCTGAGAGGTGTCGCCGTTCTTTCTAGTTTTAGACCTTCCTATAAGGGATGGAAACTTTGATGTGCGCTACCTGTTTTCCTCCCCAAAACAAGTTTTAGACCTTCCTATAAGGGATGGAAACTGATTTTGACGAGGCCATGCTTAACGTTCTTATCTTGTTTTAGACCTTCCTATAAGGGATGGAAACCTCCAGCGTCACGACGTGGTAACCGTTGGCGCATGGTTTTAGACCTTCCTATAAGGGATGGAAACATTACTCCTATGGTCTAGAACAGAAGCTCGTACACAGTTTTAGACCTTCCTATAAGGGATGGAAACTCGACAACAACGCCTGGTACTGGAAGGGGCAGCTGGTTTTAGACCTTCCTATAAGGGATGGAAACAAGGGGCCAAAAGTACCAGTGCTAACAACGCGAAAGCGTTTTAGACCTTCCTATAAGGGATGGAAACTAAATATGCCCGCCGCACCCTCACCTGCTATGGCCACGTTTTAGACCTTCCTATAAGGGATGGAAACACGCATATTTTGCGGCAATAATACTGTCTGCGGATAGTTTTAGACCTTCCTATAAGGGATGGAAACCGCAATATGACCCACAAACCGACACAGTGTCTTTTATGTTTTAGACCTTCCTATAAGGGATGGAAACTTGCAACAGAATCAGAGTTTTCGCTGTGGTCACATCGTTTTAGACCTTCCTATAAGGGATGGAAACTTCGTAGCGGATATCAAACTGGCTGAACCCCATAAGCCGTTTTAGACCTTCCTATAAGGGATGGAAACGTGGCGTTCGTATGGTTGGCCAAGAGCGGCAAGCTGAGTTTTAGACCTTCCTATAAGGGATGGAAACAGTTCCCGCCTCATTTCCAGTAGCTCCCGCACCGCCTGTTTTAGACCTTCCTATAAGGGATGGAAACCTGGCTAGACCTATAATCCTTGAGCATGACGGAAAGTTTTAGACCTTCCTATAAGGGATGGAAACCTGCTCCATCTCCCCATCGAGACGGGTTCTTCCATGTTTTAGACCTTCCTATAAGGGATGGAAACTACATCCTCCTAAGTTTTTTGGTCGGCACGTACTTAGTTTTAGACCTTCCTATAAGGGATGGAAACACAGTATGGTAACACCGCAAATCATAAGCATCATAGTTTTAGACCTTCCTATAAGGGATGGAAACCGGAAAAACAACCTTAGGTAGAATAGTCGCAAAATAGTTTTAGACCTTCCTATAAGAGATGGAAATAGTGTTTTTATGACCCGACCGATGCCGCGCAAGCAGTTTTAGACCTTCCTATAAGGGATGGAAACTCCAAACACACCTTCCAATCTAAATGTTCAATCTGAACCGTTTTAGACCTTCCTATAAGGGATGGAAACCCGCTCTATGGCGTCCGGCGGCCAACCGTGTTCATTGTTTTAGACCTTCCTATAAGGGATGGAAACACCAGTTTCGCGTTTTTCTGCGCAATAGCCACCTCGTTTTAGACCTTCCTATAAGGGATGGAAACGTGCCCATGCTGCAGAGTGTGCCGGGGCTACTTCAGGTTTTAGACCTTCCTATAAGGGATGGAAACGTGCTTGAAGGAATTACGCCTGTTTACGCTTTTTCAAGTTTTAGACCTTCCTATAAGGGATGGAAACTTGTTATCTTTGTTACCTCTCTGCGCGTCCTCTTGGTTTTAGACCTTCCTATAAGGGATGGAAACTTTGTTTCCTTCGCGCAAAGGCCGTGGGCCTATAACGGTTTTAGACCTTCCTATAAGGGATGGAAACACAAAAAGGAAAACCCCCTTTATGATCGGGCTAGACCGTTTTAGACCTTCCTATAAGGGATGGAAACTGTCGGCGCTTGGGATATCGGATTGCGGCAGCCTTGCGTTTTAGACCTTCCTATAAGGGATGGAAACACCACCTCGCCCTCCCATGTGATTTTTTCCGGCATAGGTTTTAGACCTTCCTATAAGGGATGGAAACTCCAATTCAATTGCCGTGGCGAGTTCAGCCGACAATGTTTTAGACCTTCCTATAAGGGATGGAAACCTGAAATAGTCTTTGACTGTGCCATTAACCACGGTGTTTTAGACCTTCCTATAAGGGATGGAAACTGTCGAGGATATGCATTTTCCGGGTAGCCCTCTGACGTTTTAGACCTTCCTATAAGGATTGGAAACCAAGCTGTCACAGAAGCAGTAGGTCAGTGCCTTATTGTTTTAGACCTTCCTATAAGGGTTGGAAAC

>NC_016148|2|2|279012-282019|CRISPRCasFinder
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACTATGGCTTTGGCTCTTTTATTATAGCCATTATCTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACTACATTGGCAATTTCTTTTGCTGACTTATTTTTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GGTTTTTCAACAACTGCAGCTTGGGGCTCTAAACCAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GGGGCTTTAGGCGCATCCTCCTGGCCCGTGTCACCGT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCGAACTGTTCCTCAAGCCCCCTTGTGCTGAGCCAC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GAGCGGTGACGGTGCCAGCTAGCGGGACCACAGCCA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TATGTCAGCGCCATATGTCGAGGATATGCATTTTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACGACATAGATGCACTGCTTCAGGAGCTCTTCGATG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ATGAAAATGACATAACCAGATACAAATGAAGGCGG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TAGACTTCATGCGCGACGACTTCAGTCGTCTGCCCC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TAGCAATAAGAGAAAGGAGTGAAAAACATGACTCTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ATGCCGTGCGGGCTGAGAGGTGTCGCCGTTCTTTCTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTTGATGTGCGCTACCTGTTTTCCTCCCCAAAACAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGATTTTGACGAGGCCATGCTTAACGTTCTTATCTT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTCCAGCGTCACGACGTGGTAACCGTTGGCGCATG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ATTACTCCTATGGTCTAGAACAGAAGCTCGTACACA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCGACAACAACGCCTGGTACTGGAAGGGGCAGCTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	AAGGGGCCAAAAGTACCAGTGCTAACAACGCGAAAGC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TAAATATGCCCGCCGCACCCTCACCTGCTATGGCCAC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACGCATATTTTGCGGCAATAATACTGTCTGCGGATA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CGCAATATGACCCACAAACCGACACAGTGTCTTTTAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTGCAACAGAATCAGAGTTTTCGCTGTGGTCACATC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTCGTAGCGGATATCAAACTGGCTGAACCCCATAAGCC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGGCGTTCGTATGGTTGGCCAAGAGCGGCAAGCTGA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	AGTTCCCGCCTCATTTCCAGTAGCTCCCGCACCGCCT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGGCTAGACCTATAATCCTTGAGCATGACGGAAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGCTCCATCTCCCCATCGAGACGGGTTCTTCCAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TACATCCTCCTAAGTTTTTTGGTCGGCACGTACTTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACAGTATGGTAACACCGCAAATCATAAGCATCATA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CGGAAAAACAACCTTAGGTAGAATAGTCGCAAAATA
GTTTTAGACCTTCCTATAAGAGATGGAAAT	AGTGTTTTTATGACCCGACCGATGCCGCGCAAGCA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCCAAACACACCTTCCAATCTAAATGTTCAATCTGAACC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CCGCTCTATGGCGTCCGGCGGCCAACCGTGTTCATT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACCAGTTTCGCGTTTTTCTGCGCAATAGCCACCTC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGCCCATGCTGCAGAGTGTGCCGGGGCTACTTCAG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGCTTGAAGGAATTACGCCTGTTTACGCTTTTTCAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTGTTATCTTTGTTACCTCTCTGCGCGTCCTCTTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTTGTTTCCTTCGCGCAAAGGCCGTGGGCCTATAACG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACAAAAAGGAAAACCCCCTTTATGATCGGGCTAGACC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGTCGGCGCTTGGGATATCGGATTGCGGCAGCCTTGC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACCACCTCGCCCTCCCATGTGATTTTTTCCGGCATAG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCCAATTCAATTGCCGTGGCGAGTTCAGCCGACAAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGAAATAGTCTTTGACTGTGCCATTAACCACGGT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGTCGAGGATATGCATTTTCCGGGTAGCCCTCTGAC
GTTTTAGACCTTCCTATAAGGATTGGAAAC	CAAGCTGTCACAGAAGCAGTAGGTCAGTGCCTTATT
GTTTTAGACCTTCCTATAAGGGTTGGAAAC

>NC_016148|2|2|279012-282019|CRT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACTATGGCTTTGGCTCTTTTATTATAGCCATTATCTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACTACATTGGCAATTTCTTTTGCTGACTTATTTTTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GGTTTTTCAACAACTGCAGCTTGGGGCTCTAAACCAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GGGGCTTTAGGCGCATCCTCCTGGCCCGTGTCACCGT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCGAACTGTTCCTCAAGCCCCCTTGTGCTGAGCCAC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GAGCGGTGACGGTGCCAGCTAGCGGGACCACAGCCA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TATGTCAGCGCCATATGTCGAGGATATGCATTTTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACGACATAGATGCACTGCTTCAGGAGCTCTTCGATG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ATGAAAATGACATAACCAGATACAAATGAAGGCGG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TAGACTTCATGCGCGACGACTTCAGTCGTCTGCCCC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TAGCAATAAGAGAAAGGAGTGAAAAACATGACTCTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ATGCCGTGCGGGCTGAGAGGTGTCGCCGTTCTTTCTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTTGATGTGCGCTACCTGTTTTCCTCCCCAAAACAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGATTTTGACGAGGCCATGCTTAACGTTCTTATCTT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTCCAGCGTCACGACGTGGTAACCGTTGGCGCATG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ATTACTCCTATGGTCTAGAACAGAAGCTCGTACACA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCGACAACAACGCCTGGTACTGGAAGGGGCAGCTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	AAGGGGCCAAAAGTACCAGTGCTAACAACGCGAAAGC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TAAATATGCCCGCCGCACCCTCACCTGCTATGGCCAC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACGCATATTTTGCGGCAATAATACTGTCTGCGGATA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CGCAATATGACCCACAAACCGACACAGTGTCTTTTAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTGCAACAGAATCAGAGTTTTCGCTGTGGTCACATC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTCGTAGCGGATATCAAACTGGCTGAACCCCATAAGCC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGGCGTTCGTATGGTTGGCCAAGAGCGGCAAGCTGA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	AGTTCCCGCCTCATTTCCAGTAGCTCCCGCACCGCCT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGGCTAGACCTATAATCCTTGAGCATGACGGAAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGCTCCATCTCCCCATCGAGACGGGTTCTTCCAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TACATCCTCCTAAGTTTTTTGGTCGGCACGTACTTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACAGTATGGTAACACCGCAAATCATAAGCATCATA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CGGAAAAACAACCTTAGGTAGAATAGTCGCAAAATA
GTTTTAGACCTTCCTATAAGAGATGGAAAT	AGTGTTTTTATGACCCGACCGATGCCGCGCAAGCA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCCAAACACACCTTCCAATCTAAATGTTCAATCTGAACC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CCGCTCTATGGCGTCCGGCGGCCAACCGTGTTCATT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACCAGTTTCGCGTTTTTCTGCGCAATAGCCACCTC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGCCCATGCTGCAGAGTGTGCCGGGGCTACTTCAG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGCTTGAAGGAATTACGCCTGTTTACGCTTTTTCAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTGTTATCTTTGTTACCTCTCTGCGCGTCCTCTTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTTGTTTCCTTCGCGCAAAGGCCGTGGGCCTATAACG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACAAAAAGGAAAACCCCCTTTATGATCGGGCTAGACC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGTCGGCGCTTGGGATATCGGATTGCGGCAGCCTTGC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACCACCTCGCCCTCCCATGTGATTTTTTCCGGCATAG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCCAATTCAATTGCCGTGGCGAGTTCAGCCGACAAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGAAATAGTCTTTGACTGTGCCATTAACCACGGT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGTCGAGGATATGCATTTTCCGGGTAGCCCTCTGAC
GTTTTAGACCTTCCTATAAGGATTGGAAAC	CAAGCTGTCACAGAAGCAGTAGGTCAGTGCCTTATT
GTTTTAGACCTTCCTATAAGGGTTGGAAAC

>NC_016148|2|2|279938-282019|PILER-CR
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTCCAGCGTCACGACGTGGTAACCGTTGGCGCATG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ATTACTCCTATGGTCTAGAACAGAAGCTCGTACACA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCGACAACAACGCCTGGTACTGGAAGGGGCAGCTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	AAGGGGCCAAAAGTACCAGTGCTAACAACGCGAAAGC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TAAATATGCCCGCCGCACCCTCACCTGCTATGGCCAC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACGCATATTTTGCGGCAATAATACTGTCTGCGGATA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CGCAATATGACCCACAAACCGACACAGTGTCTTTTAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTGCAACAGAATCAGAGTTTTCGCTGTGGTCACATC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTCGTAGCGGATATCAAACTGGCTGAACCCCATAAGCC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGGCGTTCGTATGGTTGGCCAAGAGCGGCAAGCTGA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	AGTTCCCGCCTCATTTCCAGTAGCTCCCGCACCGCCT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGGCTAGACCTATAATCCTTGAGCATGACGGAAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGCTCCATCTCCCCATCGAGACGGGTTCTTCCAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TACATCCTCCTAAGTTTTTTGGTCGGCACGTACTTA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACAGTATGGTAACACCGCAAATCATAAGCATCATA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CGGAAAAACAACCTTAGGTAGAATAGTCGCAAAATA
GTTTTAGACCTTCCTATAAGAGATGGAAAT	AGTGTTTTTATGACCCGACCGATGCCGCGCAAGCA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCCAAACACACCTTCCAATCTAAATGTTCAATCTGAACC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CCGCTCTATGGCGTCCGGCGGCCAACCGTGTTCATT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACCAGTTTCGCGTTTTTCTGCGCAATAGCCACCTC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGCCCATGCTGCAGAGTGTGCCGGGGCTACTTCAG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	GTGCTTGAAGGAATTACGCCTGTTTACGCTTTTTCAA
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTGTTATCTTTGTTACCTCTCTGCGCGTCCTCTTG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TTTGTTTCCTTCGCGCAAAGGCCGTGGGCCTATAACG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACAAAAAGGAAAACCCCCTTTATGATCGGGCTAGACC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGTCGGCGCTTGGGATATCGGATTGCGGCAGCCTTGC
GTTTTAGACCTTCCTATAAGGGATGGAAAC	ACCACCTCGCCCTCCCATGTGATTTTTTCCGGCATAG
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TCCAATTCAATTGCCGTGGCGAGTTCAGCCGACAAT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	CTGAAATAGTCTTTGACTGTGCCATTAACCACGGT
GTTTTAGACCTTCCTATAAGGGATGGAAAC	TGTCGAGGATATGCATTTTCCGGGTAGCCCTCTGAC
GTTTTAGACCTTCCTATAAGGATTGGAAAC	CAAGCTGTCACAGAAGCAGTAGGTCAGTGCCTTATT
GTTTTAGACCTTCCTATAAGGGTTGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016148.1\|WP_014162424.1\|270600_271389_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NC_016148.1\|WP_014162431.1\|277580_278576_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_016148.1\|WP_081468065.1\|274823_277070_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_016148.1\|WP_014162434.1\|285061_286405_-\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NC_016148.1\|WP_014162430.1\|277056_277578_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_016148.1\|WP_014162433.1\|283667_284816_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NC_016148.1\|WP_014162439.1\|291503_292076_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NC_016148.1\|WP_014162440.1\|292219_293023_-\|putative-hydro-lyase	unknown	unknown	gnl\|CDD\|180100
NC_016148.1\|WP_014162432.1\|278578_278842_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_016148.1\|WP_014162428.1\|274174_274879_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_016148.1\|WP_014162426.1\|272820_273228_+\|CRISPR-associated-protein	cas8b1	mkCas0119_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_016148.1\|WP_014162427.1\|273260_274169_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_016148.1\|WP_014162436.1\|287219_287933_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_016148.1\|WP_169311578.1\|287929_290311_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226957
NC_016148.1\|WP_014162441.1\|293019_293793_-\|LamB/YcsF-family-protein	unknown	unknown	gnl\|CDD\|235446
NC_016148.1\|WP_014162438.1\|290321_291494_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_016148.1\|WP_014162425.1\|271363_272815_+\|CRISPR-associated-protein-TM1802	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_016148.1\|WP_148256391.1\|286674_287190_+\|isochorismatase-family-protein	unknown	unknown	gnl\|CDD\|238245
NC_016148.1\|WP_014162423.1\|267654_270408_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NC_016148.1\|WP_014162442.1\|293806_294874_-\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376868

Protein	Function_ID	Function_description	E-value
NC_016148.1\|WP_014162424.1\|270600_271389_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.12405e-30
NC_016148.1\|WP_014162431.1\|277580_278576_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	4.90906e-165
NC_016148.1\|WP_081468065.1\|274823_277070_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.86853e-54
NC_016148.1\|WP_014162434.1\|285061_286405_-\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NC_016148.1\|WP_014162430.1\|277056_277578_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.41628e-60
NC_016148.1\|WP_014162433.1\|283667_284816_-\|HD-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	1.80879e-59
NC_016148.1\|WP_014162439.1\|291503_292076_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	2.13852e-47
NC_016148.1\|WP_014162440.1\|292219_293023_-\|putative-hydro-lyase	gnl\|CDD\|180100	PRK05463, PRK05463, putative hydro-lyase.	0
NC_016148.1\|WP_014162432.1\|278578_278842_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.66396e-30
NC_016148.1\|WP_014162428.1\|274174_274879_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.06095e-31
NC_016148.1\|WP_014162426.1\|272820_273228_+\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.45801e-12
NC_016148.1\|WP_014162427.1\|273260_274169_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	2.02236e-73
NC_016148.1\|WP_014162436.1\|287219_287933_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	5.85302e-106
NC_016148.1\|WP_169311578.1\|287929_290311_+\|ABC-transporter-permease	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	3.53019e-13
NC_016148.1\|WP_014162441.1\|293019_293793_-\|LamB/YcsF-family-protein	gnl\|CDD\|235446	PRK05406, PRK05406, 5-oxoprolinase subunit PxpA.	3.03782e-152
NC_016148.1\|WP_014162438.1\|290321_291494_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.63686e-29
NC_016148.1\|WP_014162425.1\|271363_272815_+\|CRISPR-associated-protein-TM1802	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	7.66381e-34
NC_016148.1\|WP_148256391.1\|286674_287190_+\|isochorismatase-family-protein	gnl\|CDD\|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	5.02586e-51
NC_016148.1\|WP_014162423.1\|267654_270408_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NC_016148.1\|WP_014162442.1\|293806_294874_-\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|376868	pfam02626, CT_A_B, Carboxyltransferase domain, subdomain A and B. Urea carboxylase (UC) catalyzes a two-step, ATP- and biotin-dependent carboxylation reaction of urea. It is composed of biotin carboxylase (BC), carboxyltransferase (CT), and biotin carboxyl carrier protein (BCCP) domains. The CT domain of UC consists of four subdomains, named A, B, C and D. This domain covers the A and B subdomains of the CT domain. This domain covers the whole length of KipA (kinase A) from Bacillus subtilis. It can also be found in S. cerevisiae urea amidolyase Dur1,2, which is a multifunctional biotin-dependent enzyme with domains for urea carboxylase and allophanate (urea carboxylate) hydrolase activity.	9.86951e-131

>NC_016148.1|WP_014162432.1|278578_278842_+|CRISPR-associated-endonuclease-Cas2
MFVIMVYDVGEKRVAKMLKTGRKYLSWVQNSVLEGELSPGLFAKLKADVLKVMDKEQDSVIFYTWRVERYSTREILGVERGASGPFI
>NC_016148.1|WP_014162431.1|277580_278576_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MGKTIYLLSSGSLSRKDNTIVVENDDGRRFIPVETTDEILVFGEVDLNKRFLEFAAQSEIILHFFNRYGYYVGTYYPREHLNSGAVIIAQARHYLELDKRLALAKRFVHGAISNMEKVISYYARRGKSELEGANEKLAEFKDNLERCSDISELMGLEGNAKDIYYSVFDEITEDEEFVFEKRTKRPPANRVNALISFLNSLCYILVLSQIYRTHMDPRIGFLHESNFRRFSLNLDIAEIFKPILVDRLIFSLINKKMIQKKSFSERGGGLYLTDKGKEVVLKAWEDRLQSTIEHKGLRRNVSYRNLVRMEVYKVEKHVLGDKLYEPFVARW
>NC_016148.1|WP_014162430.1|277056_277578_+|CRISPR-associated-protein-Cas4
MSFCSGLSEKARIGGTLVWYYFICKRQVWLMARGIEPERTNDALMIGKLLSERTYERERHNVKFGDNSFDIVRKEEGVVVVGEIKKSSRFEHAAKMQLLHYLYVLQKDGVEAEGELLFPKERKKERVKLESKTIKLLEQIYEDIHKLAEAANPPVLKRNRYCSGCAYRYWCWS
>NC_016148.1|WP_081468065.1|274823_277070_+|CRISPR-associated-helicase/endonuclease-Cas3
MWKLQDAGMMWSPGSLPGDLESHPGRPLKDHLMGTWKLAECLSERNRVPIDMEKLKWVCWTHDLGKAHCSFQKYLQGKGTKVRHAEPSAWFTLAVTNDLVCSEGVRRHHSSICNYDESKSYWACDDFKAENVNVSLKEILPSWPFMLSEHKLQELAFELLLGEKNRLEDWLRFRTIYSLFITSDRMDAMRIQKVEKSVIPQWKAKTFSVDTPMAGWRSEVRRLCVEAADNVSLPGIYSLSLPTGSGKTLIGLEMAHNWAKKMKFSNIIYALPFISIVEQNAQVASEVFGEDNVQEDHSLAYISDTETENTTPEKRMQSFFRYWDSPVVVTTLVQLWTAIFGSSANESMNFHRLSNSVVIMDEPQAIRPQLWKGFGKVLSFLSKKLNITFLLMTATKPHIVEGKELAPAGVVAKRPYKTRQECRFLDGVHDIDSLPDLLEENISRLRESSGLVVLNTKRSALKAYDMLKGILGQNDPDPILFLSGWMTPKHRKEVLGKLIGLEKEGVKRYLVSTQVVETGVDLDFQWVFRDLGPLDSIIQVAGRCNRHFSMGEPGEVVIAELMDPEKGKSFSRYVYDDVLLLASREILGKRPLFDEQDTVEMVDEYFSRILDGLKPEHIWEDIERGSWDTLPKLIEKRTKGVSLYVELDENLRNLLDELSNMTRGFENLDKARNIARKLQMYKIEVPAKSIEKWEQKLGSNFIIDGAHPVLCKLPGRDEWFLSKEGIGTVYSMETGFIPPDGDSGDEFL
>NC_016148.1|WP_014162428.1|274174_274879_+|type-I-B-CRISPR-associated-protein-Cas5
MPTVFEISGRMAMFRKPYTTTSSISYPFPPPSALAGMIAAILGYTHGAEDKGWNALYWEKMKGTQVALRIMNPVSWHSETINFWNVKEPQKKHIQVKHQFLREPRYRVFVKGPLEEELDSFLSKGCFLYTPYLGVAYALCDVKYLGRFKEEDCIPPVKVNTVIPFGDGLKVDVLGSGGVFRELVPFSMDEERSLKKSITVLFQLSPSKGILIKEKGDVEIARCGDDVVAWFPAW
>NC_016148.1|WP_014162427.1|273260_274169_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MAFEKRRELLFVYSVKDANPNGDPLNANHPRYDADSGQILVSDVRIKRTIRDQFVREGKDVFVDGEPKTLDSRVKELKEKFNVKEAREALSRCIDTRLFGVTFALGKESFSWTGPLQWKWGRSLHRAKVEFVQGTAAFATKETSEQRSFRNEYIVPFALIASYAIANQYAAETTGATSEDLDAHFDAVWVGHENLITRSKIGHKPRLLLEVAYKEGYNGVIGSMDDKIGLKKKDGSPLSEEEELALRSLENVILDAEPLVEEVISRKNFIDKVRVRKDREVYLKGLDRLQESMDLSLELEER
>NC_016148.1|WP_014162426.1|272820_273228_+|CRISPR-associated-protein
MKLDFLDEFSDPYLKEDSGKGVFLAGVALGMLAKGQAGQSGDLGNSPLFKQINFGKIQLRDLKKHLSRIPELIRAYEIPHAGMIEVLAAEAGRLIITGQKKDLGVDGNFVFAVAFMNAPKFCFEKIFKKQEEGKE
>NC_016148.1|WP_014162425.1|271363_272815_+|CRISPR-associated-protein-TM1802
MGFLEAVYSLGKRESSTDFSPEWEDIDNFLTLPLPIIEDQDRKGRIIRVWLEAEEPLGKQLEVRDIAKIDVVDFLAGEGTLQEKRRKYLYRDPVGANVTWSYSPTYKLGSPKKADREKLLEETEWKDKQDSRFYKLYNRVLADLEREGVFSKGSVDLIMTKLVERRGEICDLWSDPKRSYILMFGCEDKSVFLYPGDIPAFISYFRQKLAKKSGGGDLIKCSFCGCSEESSASFSDVFKFSTFDKVSFLPGNNKKHKNKVFPICQQCNAMFTKGKDVLRNKFSNGSIINGINIDVVPELIFGHEQLAAVADNVSDFIKKGLRIEKNLFSFLARQGEGLVFHFMFWEKNQAQERVHLIVEDVPPTRLKRLEELWRKSLEVYSPFKKDNTESKYLDFAIRNIVWVYLDLAGTGDSEKKFQMDRCFKVLGQLLNGQKVDVRGLKANMVSRFPGLFASEEWPKVGPEKSGQMLLVLDFLERVNKAGR
>NC_016148.1|WP_014162424.1|270600_271389_+|CRISPR-associated-endoribonuclease-Cas6
MKILLNLNSPQGGEIRLPRVNLHILQGFVYNLMSSNLAKFLHDEGYKIDGRKFKLFSFSWLMGKKVFDDKYVVFQDGASLVISSSLSSISQDVLNEVLQKEYLRLAGNEVFCSSVNVYTELVVEEEISIRTLSPICCYSTMYKTDGRPYTVYHAPSEQDFQRQIHNNLLKKYKLIYSERAVPEGKVTLEPLSRPRLQTALFKPDDPRPIKGWWGDFVLKGPKELLSVALDAGIGVKNSAGWGCVTLFERKGRNKYGLPRSGI
>NC_016148.1|WP_014162423.1|267654_270408_-|cation-translocating-P-type-ATPase
MGKPYYQMTVQEVLDALKTSENGLTNDEAERRLKEYGPNEITEDAAVSKWMIFLSQFKDLLVIVLIVAGFISLAIGSVRDGAIMFIIVIINALIGFFQEYKANKVLARLKELITSPAKVKRNGELTEIPQSKLVPGDIVYIEAGDKVPADLRIIEAFNLRTNEFSLTGESVSQEKNNKAIMHDCILADRENMAYMGTTVASGSAYGVVVATGMKTEMGKIAGMTQATTTTQSPLQIELGILAKWLTGIVIIISIGLFGVALWQGLGLFMSMVYALGIAVAAVPQALPAQVTVALASTSKRLAEKKAVVKNLPSVETLGSTTVICTDKTGTLTKNEMTVTKLWFDDAEYQVTGIGYEPKGEILDEKGTPISEEKIKELEIMLDAATMASNAEIHPPDDQHSGWYPIGDPTEAALITLSMKAGTRSPKEDEENPEIHEFPFDSERKRMSSVRKFGDRLQLAMKGATDSVLSVAKYIYRDGRILPLTEEDKEKIQKLNETWSKRALRVLAIAFRPLEANGQDYVLEETEKDVVFLGLVGMIDPPKEGVKEAVASCHQAKIRIIVMTGDHAITAQAIGKEIGLSEEGAPPTYTGTQMKKMSDSELTDILMSHKSIIFSRVAPEDKLRIVMLLEAQDEVVAVTGDGVNDAPALKRAAIGVAMGQKGTDVAKEAAELVLLDDSFPTLVEAVKEGRTIYKNLRKTVLASMTTNMAELMVVLLGLAGIAMKNWAIPILAIQILAIDLLAEVLPLTCLTFDPPDENIMKMPPRDRKEHIMNFKNSVEVMFLGGLIGTLAFLNFVMFMKRQGIILTPEMMENPLFARATAITYLTIAYCQFVNILSRRDDEKSLFNKAFFSNKILLGSIVWSITMVFIGIYTPYVSDFLRFEGPQISDWIFILGASGIYLAVYETMKLFRRLRMAKA
>NC_016148.1|WP_014162433.1|283667_284816_-|HD-domain-containing-protein
MFFELLYNLSLLIAIVALYDIVHDYAKTRASWRNFLMGLFFGIITVVGMHFSVHYSQGLFYDGRSVILSMAGLFGGWAPAVIAAAMAALYRVHLGGVGVYAGIASIISSAALGAIYRKHLNGEVTRIPARSLLVFSVLVHLLVIIWQAMFLPWPSVAPVALKKISVAYLTIFPIASLIVGTMLKNEERSNQLEEEKNMLIAKLREALMPLISALVKIVESKDSYTAHHQLSTAELACAIAEEMGVPKDRIEGLRLAAQVHDIGKINVPSEILNKPGKLTDLEFELIKTHVTTGYEILKDVGFLWPIARIVLEHHERENGTGYPNGLKGNELLLESKILAVADVIDAMSHHRPYRPALGIDVALKEIEKNKGILYDGQVQICV
>NC_016148.1|WP_014162434.1|285061_286405_-|sodium:alanine-symporter-family-protein
MDLAKLISTINSFLWGNLLLYLLCGTGIFFTFKLRFVQIRKLKAIFSNAFGNFSIKGEKAGKEGMSSFQSLATAVAAQVGTGNLAGAATAIASGGPGAIFWMWLSAFFGMGTIFAEAVLAQTFKVKDEDGQVVGGPAYYISQGTGSKAMAAFFAVAIIFALGFVGNMVQSNSIGDAFATAFDIPSLYVGIGIAILAGLVFFGGIGRIASVTEKIVPIMALFYIVSGLVVLGMHAENIIPSLKMIIQGAFNPKAATGGIIGATVKEAVRYGVARGLFSNEAGMGSTPHAHAVAKVKHPVQQGLVAIMGVLIDTFVVLNITALVILATGALDGQTTGIALTQSAFTKAFGSLGNPFVAVCLFFFAFSTIIGWYYFGESNIRYLFGVKGLTPYRVLVMLFIVLGSTLKVNLVWELADTFNGLMVIPNLIALLLLSKVVAKTLNEYDSGIN
>NC_016148.1|WP_148256391.1|286674_287190_+|isochorismatase-family-protein
MLLIVDMLNDFIDPKGVLFCGKSSREIIPVIKDLVEECKSKGDSVIYLADAHEKDDREFDRFPPHAVKGTWGAQVVPELAPDEEDLVIEKKRFSGFYGTELDGVLKDLAPDEVWVVGVCTSICVMDTVGDLCNRDIPVVVVENGVADFDEEFHRFALARMERVYGAKIIKW
>NC_016148.1|WP_014162436.1|287219_287933_+|ABC-transporter-ATP-binding-protein
MEQQKTLLKLEKVRKIYKMGEVEVEALKPSSLEVYEGELLVILGPSGSGKSTLLNIMGGMDSPTEGAVWFGGEDLARASERRLTEYRRHQVGFVFQFYNLIPDLTALENVAIAAELSNTPLSPRKLLEQVGMNNKMDSFPSQLSGGEQQRVAIARAAAKNPKMLLCDEPTGSLDCETGRKILSLLLDVNRQYGTTVVIVTHNVAIRAMGRRIIRMSSGAIAEMTFNERPEPPERISW
>NC_016148.1|WP_169311578.1|287929_290311_+|ABC-transporter-permease
MMRTLWRKLFRTIVSTKGQFFAVLSVIAVGITLYVAMAAVSENLIHSKDLFYAETSFADHFFHVVNAPEGIGERIKAVKGVLAATARTQKDVPVLWEGKKRANLRLTGYPMPDNGELNRVKVIGGRMFDKYPKLGAVEVLINRQFAEAHKLKPGMDLDVAAEGKRKVLTIVGIAASPEFVYTVRDAAGLLEDPSTFGAAIMPENQIQELMGRKGSVNQVLIRFAPGAQKEEIVQKIKEILQPYGLLAEYPQKDQLSEAILRGELTQLRAFSRFLPTIFLAIALLMQFVFVGRLVKTQRGQIGLLKALGYSNISLLFLYGSYAFLATTIGAFVGIALGYGLASLLVRLYSIFFNLPRLEETLRLGTAGAVAFLSITAGTTAGLAAAWGITSIRPAESMRPTFPKATKRSFLERIPILWNHLGLQWRMSFRSLSRSRFRAFVTAMGAIFSIALLVVSLFSKDSMDDLMRRHFSYDRQYDYLVRIISPVKEGEILNISRIDGVLEAEPFLELPVRIKLGRKNREDVLLAMEPSPSLVRITNQEGKELPLPEEGLLLDWFTAQKLEAKVGDELQVQSMLDLGPPRYGIFRVEGITKRAMGSASMVSLKEANRLLNEQNVVSGVMLKIDPGLSDKVERELERMVNISSVLNKKDERAYFQKNLGYMYYSIGILVLFSSVLGFAIIYNSSVIALSERKRTLAALKALGMTNQEVAVYLWSEDGFLLFWGIILGLPLGKVLSELYAVAVSTDLFSFNVIIYKSTYFLAACGGIVLGIFAWILALKGVKELKMIEILKAND
>NC_016148.1|WP_014162438.1|290321_291494_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MNKKLLLGLAGVFLLAALVWLYLSRGTEVETAFVQIGDVVRTVEEDGYVEAVGDRALYAVHGGKVSRVFVKTNDVVHKDQELIRMENKDIEASLSEIKRLLAESQRELDFYRASEEKARIALADAERTMKRYKRLYDSQEISLSEYEQATLNVEEKRRELEKARSNLLGVEARTKGLKEQLEALESKRRELIIKSPIDGYVLKLPAEEEQVVSPGELLVIVAPRGPMEIRADFLSDLLSEIKVGQKVMITAQALGDVSLKGQIDRIYPLAEEKISPLGVEQRRVPVYVSLPHVANLMPGYEVRIAVETARREQVKTLPIESVRTNSQGSSEVLKIVDGRVRIVPVDVGLKSRQKVEIVEGLDEGDVVVKDAGIELDDGAKVKAAGAFPRP
>NC_016148.1|WP_014162439.1|291503_292076_-|flavodoxin-family-protein
MKVVAFNGSPRKDGNTYELLSIVCRELEKEGIATEIAQLGNQNVRGCMACYKCFENKNRQCIINDFISDCIAKMDEADGILLGSPTYFCNVTAEMKALIDRAGMVSRANGDMFKRKVGAGVVAVRRAGAIPTFQALNTFFTFAQMIVPGSRYWNVGIGLGKKEALEDEEGIKTMEVLGQNMAWLLKKLAQ
>NC_016148.1|WP_014162440.1|292219_293023_-|putative-hydro-lyase
MTASAKDFANTHPSEIWEMIRSGQWTGPTPGMAKGYVQANLVVLPKDWAYDFMVFAQRNPKPCPVLDITEPGDPEPRMVAPGADLRTDLPKYRVWENGKLVAEPTDIRPYWRDDLVAFLLGCSFSFESALIEASIPIRHIECSCNVPMYITNIQCKPAGRLSGPMVVSMRPIPAPMVPKAVLATGRFPAVHGAPVHIGDPALIGIKDISRPDFGDPVPINDGEIPVFWACGVTPQAALMASNVPFAITHAPGHMFICSVKDADYAVF
>NC_016148.1|WP_014162441.1|293019_293793_-|LamB/YcsF-family-protein
MYRIDLNSDLGESFGAYKIGNDEAVLESVSSANVACGFHAGDPLVMLKTVRAAKAKGVQIGAHPGHPDLMGFGRRVMNCTPDEVYAYTLYQVGALQAVCKAEGLSLQHVKPHGALYNQAAKDPELAYAIACAVKDAGENLILLGLANSSFEEAAAKAKVLFASEAFADRAYEKDGSLVSRKKEGAVIHDAELAARRVVQMVKDGTVEAIDGTLIKLKPHSICLHGDTPEAVEMAKTIRSTLEKEGITISPIKEVILK
>NC_016148.1|WP_014162442.1|293806_294874_-|biotin-dependent-carboxyltransferase-family-protein
MKLEIVSGGLLTTVQDLGRWGFQGIGMPVAGAMDSFALQAGNIIVGNAPNAAALEITVMGPTINVVEGEGVICLSGAPLDMRINNEKVPHWTAIRVKGGDKISIGGPTGPGCRAYLCVSGGIDVPVIMGSRSTYLRAHIGGLEGRALQKQDTISTGELPALWHLCDGFSCPSWMIPPYGQNVPINVVLGPQDDYFTPEGIETFLSAEYTITNEADRMGYRLDGPEIEHKSGADIISDAIPLGAIQVPGSRKPVAMLADRQTTGGYTKIAVITTPHIALLAQRLPGEKVSFKKVSFEEAALALKEEKDKLRTLEIERANYRSTRKTHAASTPKAGPIQWSMKINGKNYHVTCEEIS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	AX059140	Sequence 1 from Patent WO0075335	454-485	7	0.781
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	NC_004735	Rhodothermus phage RM378, complete genome	454-485	7	0.781
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	NZ_KX009059	Pseudomonas syringae pv. actinidiae strain RT685 plasmid pMG1_RT685, complete sequence	72051-72080	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	NZ_LT963396	Pseudomonas cerasi isolate PL963 plasmid PP1, complete sequence	73269-73298	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	NZ_CP016617	Microvirga ossetica strain V5/3m plasmid unnamed1, complete sequence	1026466-1026495	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MN329674	Mycobacterium phage JoieB, complete genome	58498-58527	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MK494123	Mycobacterium phage Blackbeetle, complete genome	57911-57940	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MG757167	Mycobacterium phage Tesla, complete genome	57706-57735	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MH727562	Mycobacterium phage VasuNzinga, complete genome	57792-57821	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MK305892	Mycobacterium phage RedRaider77, complete genome	57859-57888	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	KJ538721	Mycobacterium phage MosMoris, complete genome	58329-58358	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MN428056	Mycobacterium phage Pringar, complete genome	57698-57727	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MK279842	Mycobacterium phage Raela, complete genome	58466-58495	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MK061407	Mycobacterium phage Beelzebub, complete genome	58411-58440	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	MN329676	Mycobacterium phage Poise, complete genome	57911-57940	8	0.733
NC_016148_1	1.2\|256409\|30\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256409-256438	30	KX159477	Mycobacterium phage Gattaca, complete genome	58323-58352	8	0.733
NC_016148_1	1.3\|256469\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256469-256500	32	NZ_CP032313	Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence	146785-146816	8	0.75
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	NZ_CP024582	Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence	172809-172840	8	0.75
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1244701-1244732	8	0.75
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	NZ_CP025188	Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence	232625-232656	8	0.75
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	167411-167441	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP027518	Enterococcus faecium strain AUSMDU00004024 plasmid unnamed1, complete sequence	168344-168374	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_LR135476	Enterococcus faecium isolate E8423 plasmid 2	169221-169251	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_LR135358	Enterococcus faecium isolate E7948 plasmid 2	187499-187529	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP040741	Enterococcus faecium strain VRE1 plasmid pVRE1-1, complete sequence	182495-182525	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	MN693289	Marine virus AFVG_25M43, complete genome	7365-7395	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP013995	Enterococcus faecium strain 6E6 plasmid unnamed1, complete sequence	62573-62603	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_LR135279	Enterococcus faecium isolate E6975 plasmid 2	26922-26952	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_LR135429	Enterococcus faecium isolate E8927 plasmid 2	55368-55398	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP045013	Enterococcus faecium strain LAC7.2 plasmid pI, complete sequence	53656-53686	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP035655	Enterococcus faecium strain UAMSEF_08 plasmid unnamed1, complete sequence	59323-59353	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP035661	Enterococcus faecium strain UAMSEF_09 plasmid unnamed1, complete sequence	52954-52984	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP035667	Enterococcus faecium strain UAMSEF_20 plasmid unnamed1, complete sequence	52954-52984	8	0.742
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_CP035649	Enterococcus faecium strain UAMSEF_01 plasmid unnamed1, complete sequence	59324-59354	8	0.742
NC_016148_2	2.9\|279572\|35\|NC_016148\|CRISPRCasFinder,CRT	279572-279606	35	NC_009705	Yersinia pseudotuberculosis IP 31758 plasmid p_153kb, complete sequence	92355-92389	8	0.771
NC_016148_2	2.17\|280099\|35\|NC_016148\|CRISPRCasFinder,CRT,PILER-CR	280099-280133	35	NC_017311	Desulfovibrio vulgaris RCH1 plasmid pDEVAL01, complete sequence	72558-72592	8	0.771
NC_016148_2	2.17\|280099\|35\|NC_016148\|CRISPRCasFinder,CRT,PILER-CR	280099-280133	35	NC_005863	Desulfovibrio vulgaris str. Hildenborough plasmid pDV, complete sequence	78001-78035	8	0.771
NC_016148_2	2.17\|280099\|35\|NC_016148\|CRISPRCasFinder,CRT,PILER-CR	280099-280133	35	NC_008741	Desulfovibrio vulgaris DP4 plasmid pDVUL01, complete sequence	125872-125906	8	0.771
NC_016148_1	1.1\|256346\|33\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256346-256378	33	NZ_CP046332	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2	99192-99224	9	0.727
NC_016148_1	1.1\|256346\|33\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256346-256378	33	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	270648-270680	9	0.727
NC_016148_1	1.1\|256346\|33\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256346-256378	33	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	40270-40302	9	0.727
NC_016148_1	1.1\|256346\|33\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256346-256378	33	NZ_CP017750	Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence	496348-496380	9	0.727
NC_016148_1	1.1\|256346\|33\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256346-256378	33	NZ_CP032520	Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence	21216-21248	9	0.727
NC_016148_1	1.1\|256346\|33\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256346-256378	33	NC_006466	Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence	89797-89829	9	0.727
NC_016148_1	1.5\|256594\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256594-256624	31	NZ_CP046163	Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence	945800-945830	9	0.71
NC_016148_1	1.5\|256594\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256594-256624	31	NZ_CP046066	Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence	1129186-1129216	9	0.71
NC_016148_1	1.5\|256594\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256594-256624	31	NZ_CP045356	Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence	630718-630748	9	0.71
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	1004499-1004530	9	0.719
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_LT670852	Candidatus Erwinia haradaeae strain ErCipseudotaxifoliae isolate 3056 plasmid pl1	5459-5489	9	0.71
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	NZ_LR217726	Candidatus Erwinia haradaeae strain ErCipseudotaxifoliae isolate 3056 plasmid pBioThi	1363-1393	9	0.71
NC_016148_1	1.13\|257109\|31\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257109-257139	31	CP031730	Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence	313098-313128	9	0.71
NC_016148_1	1.18\|257433\|37\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257433-257469	37	MG945615	UNVERIFIED: Microviridae sp. isolate 5040-1801, complete genome	318-354	9	0.757
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	784259-784290	10	0.688
NC_016148_1	1.6\|256655\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256655-256686	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	643197-643228	10	0.688
NC_016148_1	1.23\|257757\|35\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257757-257791	35	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1024185-1024219	10	0.714
NC_016148_1	1.23\|257757\|35\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257757-257791	35	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	1469347-1469381	10	0.714
NC_016148_1	1.23\|257757\|35\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257757-257791	35	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1024293-1024327	10	0.714
NC_016148_1	1.23\|257757\|35\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257757-257791	35	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1424453-1424487	10	0.714
NC_016148_1	1.23\|257757\|35\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	257757-257791	35	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	1381147-1381181	10	0.714
NC_016148_2	2.14\|279902\|36\|NC_016148\|CRISPRCasFinder,CRT	279902-279937	36	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	562580-562615	10	0.722
NC_016148_1	1.3\|256469\|32\|NC_016148\|PILER-CR,CRISPRCasFinder,CRT	256469-256500	32	NZ_CP023721	Rhodococcus sp. H-CA8f plasmid unnamed, complete sequence	2924-2955	11	0.656
NC_016148_2	2.14\|279902\|36\|NC_016148\|CRISPRCasFinder,CRT	279902-279937	36	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1611816-1611851	11	0.694
NC_016148_2	2.15\|279968\|35\|NC_016148\|CRISPRCasFinder,CRT,PILER-CR	279968-280002	35	NZ_CP033582	Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence	253588-253622	11	0.686

1. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to AX059140 (Sequence 1 from Patent WO0075335) position: , mismatch: 7, identity: 0.781

tagcgccggcatgaagaagggcgcccctccta	CRISPR spacer
cagaaacggcatgaagtagggcgcgcctccaa	Protospacer
.** . ********** ******* ***** *

2. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NC_004735 (Rhodothermus phage RM378, complete genome) position: , mismatch: 7, identity: 0.781

tagcgccggcatgaagaagggcgcccctccta	CRISPR spacer
cagaaacggcatgaagtagggcgcgcctccaa	Protospacer
.** . ********** ******* ***** *

3. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX009059 (Pseudomonas syringae pv. actinidiae strain RT685 plasmid pMG1_RT685, complete sequence) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
atttgtggcgcccgccccgtttcgcctgat	Protospacer
  ** *********** ********.   *

4. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT963396 (Pseudomonas cerasi isolate PL963 plasmid PP1, complete sequence) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
atttgtggcgcccgccccgtttcgcctgat	Protospacer
  ** *********** ********.   *

5. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016617 (Microvirga ossetica strain V5/3m plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
catgcgtgcgccagccacgtttcggtattt	Protospacer
..* .  ***** *********** *****

6. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MN329674 (Mycobacterium phage JoieB, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

7. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MK494123 (Mycobacterium phage Blackbeetle, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

8. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MG757167 (Mycobacterium phage Tesla, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

9. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MH727562 (Mycobacterium phage VasuNzinga, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

10. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MK305892 (Mycobacterium phage RedRaider77, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

11. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to KJ538721 (Mycobacterium phage MosMoris, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

12. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MN428056 (Mycobacterium phage Pringar, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

13. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MK279842 (Mycobacterium phage Raela, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

14. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MK061407 (Mycobacterium phage Beelzebub, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

15. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MN329676 (Mycobacterium phage Poise, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

16. spacer 1.2|256409|30|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to KX159477 (Mycobacterium phage Gattaca, complete genome) position: , mismatch: 8, identity: 0.733

tgttttggcgcccgccacgtttcgctattt	CRISPR spacer
tcgtttggcgcgcgccacgttgcgcttcag	Protospacer
*  ******** ********* **** .

17. spacer 1.3|256469|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032313 (Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence) position: , mismatch: 8, identity: 0.75

gttacgctcacgataggcaagctccagtattt	CRISPR spacer
ctcaaggtcgcgataggcaagctccaggatcc	Protospacer
 *.* * **.***************** **..

18. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024582 (Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgccggcatgaagaagggcgcccctccta	CRISPR spacer
ttccgccgccatcaagaagggcgccctgccgg	Protospacer
*  ***** *** *************. ** .

19. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgccggcatgaagaagggcgcccctccta	CRISPR spacer
ccgcgccggcctgaagaaggacgcctgaccca	Protospacer
. ******** *********.****.  **.*

20. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025188 (Roseomonas mucosa strain AD2 plasmid p1-AD2, complete sequence) position: , mismatch: 8, identity: 0.75

tagcgccggcatgaagaagggcgcccctccta	CRISPR spacer
ttccgccgccatcaagaagggcgccctgccgg	Protospacer
*  ***** *** *************. ** .

21. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
aaaggtccaaatattatatattattgccacc	Protospacer
*    ************** ******.**

22. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027518 (Enterococcus faecium strain AUSMDU00004024 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

23. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135476 (Enterococcus faecium isolate E8423 plasmid 2) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

24. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135358 (Enterococcus faecium isolate E7948 plasmid 2) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

25. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040741 (Enterococcus faecium strain VRE1 plasmid pVRE1-1, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

26. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MN693289 (Marine virus AFVG_25M43, complete genome) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cattctacaaatataatattttattgttaaa	Protospacer
  .*.* ******* ************.**.

27. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013995 (Enterococcus faecium strain 6E6 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

28. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135279 (Enterococcus faecium isolate E6975 plasmid 2) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

29. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135429 (Enterococcus faecium isolate E8927 plasmid 2) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

30. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045013 (Enterococcus faecium strain LAC7.2 plasmid pI, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

31. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035655 (Enterococcus faecium strain UAMSEF_08 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

32. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035661 (Enterococcus faecium strain UAMSEF_09 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

33. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035667 (Enterococcus faecium strain UAMSEF_20 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

34. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035649 (Enterococcus faecium strain UAMSEF_01 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

acctttccaaatattatattttattgtcaag	CRISPR spacer
cgttattcaaaaattatatttaattgtcaat	Protospacer
  .* *.**** ********* ********

35. spacer 2.9|279572|35|NC_016148|CRISPRCasFinder,CRT matches to NC_009705 (Yersinia pseudotuberculosis IP 31758 plasmid p_153kb, complete sequence) position: , mismatch: 8, identity: 0.771

atgaaaatgacataaccagatacaaatgaaggcgg	CRISPR spacer
attttaatgacatatccagatgcaaatgaactccg	Protospacer
**   ********* ******.********  * *

36. spacer 2.17|280099|35|NC_016148|CRISPRCasFinder,CRT,PILER-CR matches to NC_017311 (Desulfovibrio vulgaris RCH1 plasmid pDEVAL01, complete sequence) position: , mismatch: 8, identity: 0.771

tcgacaacaacgcctggtactggaaggggcagctg	CRISPR spacer
tcgacatcaacgcccggtactggaattcgctgatt	Protospacer
****** *******.**********   ** * *

37. spacer 2.17|280099|35|NC_016148|CRISPRCasFinder,CRT,PILER-CR matches to NC_005863 (Desulfovibrio vulgaris str. Hildenborough plasmid pDV, complete sequence) position: , mismatch: 8, identity: 0.771

tcgacaacaacgcctggtactggaaggggcagctg	CRISPR spacer
tcgacatcaacgcccggtactggaattcgctgatt	Protospacer
****** *******.**********   ** * *

38. spacer 2.17|280099|35|NC_016148|CRISPRCasFinder,CRT,PILER-CR matches to NC_008741 (Desulfovibrio vulgaris DP4 plasmid pDVUL01, complete sequence) position: , mismatch: 8, identity: 0.771

tcgacaacaacgcctggtactggaaggggcagctg	CRISPR spacer
tcgacatcaacgcccggtactggaattcgctgatt	Protospacer
****** *******.**********   ** * *

39. spacer 1.1|256346|33|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046332 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2) position: , mismatch: 9, identity: 0.727

cgtcccgtcgctcacattgtgggcacattacca	CRISPR spacer
agatagtacgctcagattgcgggcacattacca	Protospacer
 * .    ****** ****.*************

40. spacer 1.1|256346|33|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

cgtcccgtcgctcacattgtgggcacattacca	CRISPR spacer
agatagtacgctcagattgcgggcacattacca	Protospacer
 * .    ****** ****.*************

41. spacer 1.1|256346|33|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

cgtcccgtcgctcacattgtgggcacattacca	CRISPR spacer
agatagtacgctcagattgcgggcacattacca	Protospacer
 * .    ****** ****.*************

42. spacer 1.1|256346|33|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017750 (Cupriavidus sp. USMAA2-4 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

cgtcccgtcgctcacattgtgggcacattacca	CRISPR spacer
agatagtacgctcagattgcgggcacattacca	Protospacer
 * .    ****** ****.*************

43. spacer 1.1|256346|33|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032520 (Cupriavidus oxalaticus strain T2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

cgtcccgtcgctcacattgtgggcacattacca	CRISPR spacer
agatagtacgctcagattgcgggcacattacca	Protospacer
 * .    ****** ****.*************

44. spacer 1.1|256346|33|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NC_006466 (Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence) position: , mismatch: 9, identity: 0.727

cgtcccgtcgctcacattgtgggcacattacca	CRISPR spacer
agatagtacgctcagattgcgggcacattacca	Protospacer
 * .    ****** ****.*************

45. spacer 1.5|256594|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046163 (Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence) position: , mismatch: 9, identity: 0.71

aaataaactgagctttgtttagagtttcttt	CRISPR spacer
ctgctccttgagctttgttttgagtttcttt	Protospacer
  ..   .************ **********

46. spacer 1.5|256594|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046066 (Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence) position: , mismatch: 9, identity: 0.71

aaataaactgagctttgtttagagtttcttt	CRISPR spacer
ctgctccttgagctttgttttgagtttcttt	Protospacer
  ..   .************ **********

47. spacer 1.5|256594|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045356 (Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence) position: , mismatch: 9, identity: 0.71

aaataaactgagctttgtttagagtttcttt	CRISPR spacer
ctgctccttgagctttgttttgagtttcttt	Protospacer
  ..   .************ **********

48. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.719

tagcgccggcatgaagaagggcgccc----ctccta	CRISPR spacer
cgtcgccgccatgaaggagggcgcccgggact----	Protospacer
.. ***** *******.*********    **

49. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT670852 (Candidatus Erwinia haradaeae strain ErCipseudotaxifoliae isolate 3056 plasmid pl1) position: , mismatch: 9, identity: 0.71

acctttccaaatattatattttattgtcaag	CRISPR spacer
ttattttcaaagattatattttattgctcac	Protospacer
 . ***.**** **************.. *

50. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR217726 (Candidatus Erwinia haradaeae strain ErCipseudotaxifoliae isolate 3056 plasmid pBioThi) position: , mismatch: 9, identity: 0.71

acctttccaaatattatattttattgtcaag	CRISPR spacer
ttattttcaaagattatattttattgctcac	Protospacer
 . ***.**** **************.. *

51. spacer 1.13|257109|31|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to CP031730 (Stenotrophomonas rhizophila strain GA1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

acctttccaaatattatattttattgtcaag	CRISPR spacer
tttgtgtaaaatattatattttcttgtcgag	Protospacer
 .. * . ************** *****.**

52. spacer 1.18|257433|37|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to MG945615 (UNVERIFIED: Microviridae sp. isolate 5040-1801, complete genome) position: , mismatch: 9, identity: 0.757

ctgaaaatattttttcagcgctgaatatgggagaatg	CRISPR spacer
ttataaatattttttctgcgctgagtatggtaaattc	Protospacer
.*. ************ *******.***** *.* *

53. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

tagcgccggcatgaagaagggcgcccctccta	CRISPR spacer
ggtcgccggcacgaagaagcgcgcccgcgtga	Protospacer
 . ********.******* ****** . . *

54. spacer 1.6|256655|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 10, identity: 0.688

tagcgccggcatgaagaagggcgcccctccta	CRISPR spacer
ggtcgccggcacgaagaagcgcgcccgcgtga	Protospacer
 . ********.******* ****** . . *

55. spacer 1.23|257757|35|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

ccttggacagccaccaccttgcccacataggcaaa	CRISPR spacer
ggctcgcggcccaccaccttgcccacgtcggcaaa	Protospacer
  .* *  . ****************.* ******

56. spacer 1.23|257757|35|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.714

ccttggacagccaccaccttgcccacataggcaaa	CRISPR spacer
ggctcgcggcccaccaccttgcccacgtcggcaaa	Protospacer
  .* *  . ****************.* ******

57. spacer 1.23|257757|35|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

ccttggacagccaccaccttgcccacataggcaaa	CRISPR spacer
ggctcgcggcccaccaccttgcccacgtcggcaaa	Protospacer
  .* *  . ****************.* ******

58. spacer 1.23|257757|35|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

ccttggacagccaccaccttgcccacataggcaaa	CRISPR spacer
ggctcgcggcccaccaccttgcccacgtcggcaaa	Protospacer
  .* *  . ****************.* ******

59. spacer 1.23|257757|35|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.714

ccttggacagccaccaccttgcccacataggcaaa	CRISPR spacer
ggctcgcggcccaccaccttgcccacgtcggcaaa	Protospacer
  .* *  . ****************.* ******

60. spacer 2.14|279902|36|NC_016148|CRISPRCasFinder,CRT matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 10, identity: 0.722

tgattttgacgaggccatgcttaacgttcttatctt	CRISPR spacer
atcacttgccgaggccatgcttaacgtttttgactg	Protospacer
    .*** *******************.**. **

61. spacer 1.3|256469|32|NC_016148|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023721 (Rhodococcus sp. H-CA8f plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.656

gttacgctcacgataggcaagctccagtattt	CRISPR spacer
aaagggcacacgataggcaagctgcagtcgag	Protospacer
.  . ** *************** ****

62. spacer 2.14|279902|36|NC_016148|CRISPRCasFinder,CRT matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 11, identity: 0.694

tgattttgacgaggccatgcttaacgttcttatctt	CRISPR spacer
atcacttgccgaggccatgcttaacgtttttgattg	Protospacer
    .*** *******************.**. .*

63. spacer 2.15|279968|35|NC_016148|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033582 (Streptomyces sp. ADI95-16 plasmid pADI95-16a, complete sequence) position: , mismatch: 11, identity: 0.686

ctccagcgtcacgacgtggtaaccgttggcgcatg	CRISPR spacer
gtccagcgtcgcgacctggtaaccgtccatcgccg	Protospacer
 *********.**** **********. ..   .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

951445 : 959286

Staphylococcus_phage(33.33%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_169311626.1\|951445_952867_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	2.1e-49	31.7
WP_148256415.1\|953035_954484_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_014163051.1\|954458_955592_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	3.8e-54	34.4
WP_014163052.1\|955564_956227_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	2.5e-18	34.2
WP_148256416.1\|956270_957494_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.1e-113	52.9
WP_014163054.1\|957530_958022_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.4e-37	53.0
WP_014163055.1\|958014_959286_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	6.7e-100	56.7

DBSCAN-SWA_2

1199246 : 1211473

Synechococcus_phage(44.44%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148256421.1\|1199246_1201052_-	elongation factor 4	A0A2K9L2P9	Tupanvirus	2.0e-20	45.9
WP_014163294.1\|1201329_1202049_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	1.5e-48	43.9
WP_014163295.1\|1202048_1202303_+	phosphoribosylformylglycinamidine synthase subunit PurS	M4QPE7	Synechococcus_phage	2.7e-08	36.1
WP_014163296.1\|1202299_1203007_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_014163297.1\|1203007_1205161_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	9.8e-144	38.1
WP_014163298.1\|1205168_1206551_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.3e-56	32.1
WP_014163299.1\|1206534_1207524_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D8KLC2	Synechococcus_phage	6.0e-64	44.4
WP_014163300.1\|1207520_1208114_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.0e-31	38.3
WP_014163301.1\|1208113_1209643_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.7e-49	39.6
WP_014163302.1\|1209678_1210962_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_014163303.1\|1210954_1211473_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.0e-22	43.2

DBSCAN-SWA_3

1416254 : 1476160

Paenibacillus_phage(12.5%)

protease,transposase,integrase,tRNA

attL 1407175:1407234|attR 1467391:1468789

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1407175:1407234	attL	NA	NA	NA	NA
WP_041446086.1\|1416254_1417568_-\|tRNA	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase MtaB	NA	NA	NA	NA
WP_014163491.1\|1417588_1418302_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_014163492.1\|1418270_1419158_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_014163493.1\|1419201_1420320_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	3.6e-33	34.6
WP_014163494.1\|1420338_1422168_-	molecular chaperone DnaK	F2Y2E1	Organic_Lake_phycodnavirus	3.9e-133	52.0
WP_014163495.1\|1422184_1422829_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_014163496.1\|1422828_1423857_-	heat-inducible transcription repressor HrcA	NA	NA	NA	NA
WP_014163497.1\|1424036_1425392_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_014163498.1\|1425625_1426276_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_148256351.1\|1426342_1427788_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_148256352.1\|1427885_1429112_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	1.3e-15	29.1
WP_014163501.1\|1429112_1429598_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_148256353.1\|1429670_1430375_+	hypothetical protein	NA	NA	NA	NA
WP_014163503.1\|1430393_1430594_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_052299933.1\|1430586_1432779_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.4e-84	33.0
WP_014163505.1\|1432898_1433387_+	hypothetical protein	NA	NA	NA	NA
WP_014163506.1\|1433386_1434073_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_014163507.1\|1434175_1434346_+	hypothetical protein	NA	NA	NA	NA
WP_014163508.1\|1434437_1436057_-	carbon starvation protein A	NA	NA	NA	NA
WP_148256354.1\|1436111_1436582_-	hypothetical protein	NA	NA	NA	NA
WP_014163510.1\|1436878_1438165_-	adenylosuccinate synthase	A0A160ER07	Powai_lake_megavirus	4.9e-74	37.6
WP_014163511.1\|1438167_1438884_-	divergent polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_014163512.1\|1438962_1440177_-	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	2.6e-24	28.5
WP_014163513.1\|1440216_1441422_-	M23 family metallopeptidase	A0A292GJG6	Xanthomonas_phage	1.3e-23	46.2
WP_014163514.1\|1441440_1442328_-	ABC transporter permease	NA	NA	NA	NA
WP_014163515.1\|1442314_1443010_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	5.9e-26	35.3
WP_014163516.1\|1443012_1443957_-	transketolase	NA	NA	NA	NA
WP_014163517.1\|1443949_1444813_-	transketolase	NA	NA	NA	NA
WP_014163518.1\|1444819_1445845_-	polysaccharide pyruvyl transferase CsaB	NA	NA	NA	NA
WP_014163519.1\|1445841_1447749_-	hypothetical protein	NA	NA	NA	NA
WP_148256426.1\|1447745_1448333_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_014163521.1\|1448338_1448581_-	DUF4321 domain-containing protein	NA	NA	NA	NA
WP_014163522.1\|1448587_1449391_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_052299887.1\|1449394_1450207_-	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_014162180.1\|1450249_1451482_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	5.2e-142	62.0
WP_081468110.1\|1451566_1452415_-	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_014163523.1\|1452451_1454176_-	ribonuclease J	NA	NA	NA	NA
WP_014163524.1\|1454205_1455492_-	class II fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_014163525.1\|1455895_1457068_-	RNA-splicing ligase RtcB	H7BV18	unidentified_phage	2.2e-65	38.4
WP_014163526.1\|1457099_1457510_-	adenosylmethionine decarboxylase	I3ULD5	Synechococcus_phage	9.6e-16	34.9
WP_014163527.1\|1457998_1459162_+\|integrase	integrase	NA	NA	NA	NA
WP_169311615.1\|1459266_1461009_+	phosphodiester glycosidase family protein	A0A291LB83	Escherichia_phage	6.3e-08	41.2
WP_014163529.1\|1460990_1461875_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_014163530.1\|1462029_1462338_+	MTH1187 family thiamine-binding protein	NA	NA	NA	NA
WP_014163531.1\|1462396_1463911_-	Na+/H+ antiporter NhaC	NA	NA	NA	NA
WP_014163532.1\|1464019_1464430_-	hypothetical protein	NA	NA	NA	NA
WP_041446097.1\|1464594_1465866_-	lysine 2,3-aminomutase	NA	NA	NA	NA
WP_014162180.1\|1466106_1467339_-\|transposase	IS256 family transposase	A0A0K2CZ57	Paenibacillus_phage	5.2e-142	62.0
WP_014163534.1\|1467489_1467900_+	hypothetical protein	NA	NA	NA	NA
WP_014163535.1\|1468004_1468514_+	transcription repressor NadR	NA	NA	NA	NA
WP_014163536.1\|1468536_1468731_+	hypothetical protein	NA	NA	NA	NA
WP_014163537.1\|1468727_1470170_+	sodium:solute symporter family protein	NA	NA	NA	NA
1467391:1468789	attR	NA	NA	NA	NA
WP_014163538.1\|1470220_1470868_-	class II aldolase/adducin family protein	A0A077SK32	Escherichia_phage	1.2e-17	34.9
WP_014163539.1\|1470967_1471813_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_014163540.1\|1471864_1472749_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_014163541.1\|1472789_1473623_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A1V0SCZ1	Indivirus	4.5e-12	24.7
WP_014163542.1\|1473697_1476160_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.5e-127	40.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_016148

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection