CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017348	Staphylococcus aureus subsp. aureus LGA251 plasmid pLGA251, complete sequence	0 crisprs	NA	0	0	0	0
NC_017349	Staphylococcus aureus subsp. aureus LGA251, complete genome	9 crisprs	DinG,csa3,cas3,DEDDh,WYL	8	2	6	1

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_017349_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_1

865716-865851

Orphan

Consensus_repeat	Method
TGGCGGGGCCCCAACATAGAG	PILER-CR

2 spacers

The CRISPR arrays of NC_017349_1

>merge|NC_017349|1|865716-865851|PILER-CR
TTGCGGGGCCCCAACATAGAGGATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGGGGGCGAGGCCCCAACATAGTAGCTGGCGGAAAGGCAGCATACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAG

>NC_017349|1|1|865716-865851|PILER-CR
TTGCGGGGCCCCAACATAGAG	GATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGG
GGGCGAGGCCCCAACATAGTA	GCTGGCGGAAAGGCAGCATACAATAATGTGCAAGT
TGGCGGGGCCCCAACATAGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_000205569.1\|868605_869913_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NC_017349.1\|WP_078064649.1\|861417_861630_+\|pathogenicity-island-family-protein	unknown	unknown	unknown
NC_017349.1\|WP_173361317.1\|864375_864768_+\|DUF1433-domain-containing-protein	unknown	unknown	gnl\|CDD\|284628
NC_017349.1\|WP_000935289.1\|862270_862630_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000391592.1\|874636_875542_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235254
NC_017349.1\|WP_000168845.1\|867746_868508_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NC_017349.1\|WP_001293082.1\|861626_862196_+\|terminase-small-subunit	unknown	unknown	gnl\|CDD\|226251
NC_017349.1\|WP_000449694.1\|859903_860137_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_001190614.1\|859548_859890_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_001074405.1\|871873_873271_+\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NC_017349.1\|WP_001010508.1\|871258_871723_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_017349.1\|WP_001145730.1\|873338_874388_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_017349.1\|WP_000143212.1\|874499_874700_+\|excisionase	unknown	unknown	unknown
NC_017349.1\|WP_001193445.1\|860147_860669_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NC_017349.1\|WP_000369273.1\|863137_864349_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000771351.1\|860758_861286_+\|spore-coat-protein	unknown	unknown	gnl\|CDD\|227864
NC_017349.1\|WP_000362904.1\|862746_863136_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_001183851.1\|866566_867418_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NC_017349.1\|WP_001006453.1\|870018_871269_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_017349.1\|WP_000752917.1\|866138_866333_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_173361317.1\|864375_864768_+\|DUF1433-domain-containing-protein	gnl\|CDD\|284628	pfam07252, DUF1433, Protein of unknown function (DUF1433). This family contains a number of hypothetical bacterial proteins of unknown function approximately 100 residues in length.	3.16762e-21
NC_017349.1\|WP_000391592.1\|874636_875542_-\|hypothetical-protein	gnl\|CDD\|235254	PRK04203, rpl1P, 50S ribosomal protein L1P; Reviewed.	0.00797365
NC_017349.1\|WP_001010508.1\|871258_871723_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	6.42482e-68
NC_017349.1\|WP_001293082.1\|861626_862196_+\|terminase-small-subunit	gnl\|CDD\|226251	COG3728, XtmA, Phage terminase, small subunit [DNA replication, recombination, and repair].	3.04422e-68
NC_017349.1\|WP_001074405.1\|871873_873271_+\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_017349.1\|WP_000168845.1\|867746_868508_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NC_017349.1\|WP_001145730.1\|873338_874388_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.12066e-36
NC_017349.1\|WP_000205569.1\|868605_869913_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	7.11107e-136
NC_017349.1\|WP_000771351.1\|860758_861286_+\|spore-coat-protein	gnl\|CDD\|227864	COG5577, COG5577, Spore coat protein [Cell envelope biogenesis, outer membrane].	8.07326e-36
NC_017349.1\|WP_001183851.1\|866566_867418_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	2.01779e-76
NC_017349.1\|WP_001193445.1\|860147_860669_+\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.00510505
NC_017349.1\|WP_001006453.1\|870018_871269_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_017349.1\|WP_000752917.1\|866138_866333_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07

>NC_017349.1|WP_173361317.1|864375_864768_+|DUF1433-domain-containing-protein
MNRKMIIIFISIILISGGVYLKMKHDQKQKYYDEQKERIIIYMKYNVKGYKEINFEEQKENPLDGFVITGYINNDKTNTFSAHMWSKDDYQFEYLSTYSGYIAKNMPENPKSVSEIKKEQSNKKDKKNDD
>NC_017349.1|WP_000369273.1|863137_864349_-|hypothetical-protein
MDNLHTKDNTYHELAGNVYNTKSSDKETKIEDANGALHNFKIQASRVDKVNGFQAMAVSPKDSKGNVDNETVYFVYAGTDKYEPADISTDIYLGTNDIKIETNPNKILNAAIYRDTSLKEINPSTVGNNKWLEMVDKNNAKEADQFNEAYLWTQSVLNKGNYKHVYGAGHSLGGTIAQVMTVLFNFDKTKTFSAPNGYNMLPDNVKENLDLSKYNQTITDYAHPNDKIGIATLGSSILGTEILADDSELSKLFFNPISGHGIDTFEFSGGSVKIKVDGKKANQMAREMRDKLHNIDKAIKALEKYMENTKKQAKQIESKYVNKLLSGSHEFISPSDIENYVEELSKSGHYDFFDEALFEDTIGELKYTKQRLSQFSEKIIDATKKFEDRDKEISEIYRWFEGG
>NC_017349.1|WP_000362904.1|862746_863136_-|hypothetical-protein
MDLFKEIRDVSNEIGEGIHDATDAIKKEVEKDAKIAMEKAHLFALKHELKNEIQSMISDEKEDIENCISSLDEIESILKDQSSKLEGAFEGKTSDAIAFNLATEQSKLMDLTESYDDCKKSCKTYDGWF
>NC_017349.1|WP_000935289.1|862270_862630_-|hypothetical-protein
MLNTIITSIFLFIFFLPFFCIGFFIITLIRDLTRNFNNIKVTYNTFTYYETGKTILELRYFIWERRKRKYFIDLIERSEIIHLAGNKEIVRGMYYVDASPLKGNNKKSFLRKCIQIFEK
>NC_017349.1|WP_001293082.1|861626_862196_+|terminase-small-subunit
MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLKKPHIKQYIQEQKDKIIDENVLTAKELLHVLTNTAVGDETETKEVVVKRGEYKENPQSGKVQLVYNEHVELIEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGDDEELDKAVQDVSNANPNHTVIVDDIPLED
>NC_017349.1|WP_078064649.1|861417_861630_+|pathogenicity-island-family-protein
MADDNIDDHIIKNHLEMIVDRVATDKEFYIFDSLIQGRSYQDISSVLDCSEQSVRFWYETLLDKIVEVIE
>NC_017349.1|WP_000771351.1|860758_861286_+|spore-coat-protein
MKLLKTKHCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKARLQNYKNRSISNMALLKNVLNYYTEEEKKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSYVKVV
>NC_017349.1|WP_001193445.1|860147_860669_+|hypothetical-protein
MQTIKEIDKYKNNIHEYGNDINKLESNVNDVKNELASKNKEYQDLVINGKVEQADKLYSEIEKLEADYRVKNKRLTVMKRSLKQVVIKNCESMTQVADRLRDEYINVYHDDLNNYEQLKQELQEAENKLKAHNNEYYTKQRELSRYIDGKRRENDIQNIEFVGAVNIIEPFNV
>NC_017349.1|WP_000449694.1|859903_860137_+|hypothetical-protein
METNQYEELSEVLELTESQKLRLYVYQERQNKNINQDDKDAIQNTEEEKREKRQKILDIKDDVTRQNAIAKNRELFN
>NC_017349.1|WP_001190614.1|859548_859890_+|hypothetical-protein
MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGSMKRYEALKRIEV
>NC_017349.1|WP_000752917.1|866138_866333_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NC_017349.1|WP_001183851.1|866566_867418_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NC_017349.1|WP_000168845.1|867746_868508_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NC_017349.1|WP_000205569.1|868605_869913_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNIKYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NC_017349.1|WP_001006453.1|870018_871269_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
>NC_017349.1|WP_001010508.1|871258_871723_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MNFNNLDQLYRSVIMDHYKNPRNKGVLDNGSMTVDMNNPTCGDRIRLTFDIEDGIIKDAKFEGEGCSISMASASMMTQAVKGHSLGEAMQMSQEFTKMMLGEDYVITEEMGDIEALQGVSQFPARIKCATLAWKALEKGTVAKEGKAEGTTEEE
>NC_017349.1|WP_001074405.1|871873_873271_+|Fe-S-cluster-assembly-protein-SufB
MAKKAPDVGDYKYGFHDDDVSIFRSERGLTENIVREISNMKNEPEWMLDFRLKSLKLFYKMPMPQWGGDLSELNFDDITYYVKPSEQAERSWDEVPEEIKRTFDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEEKGIIFKDTDSALQENEELFKKYFASVVPAADNKFAALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLIIADEGASVHYVEGCTAPVYTTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRTFVYENGNMEWVDGNLGSKLTMKYPNCVLLGEGAKGSTLSIAFAGKGQVQDAGAKMIHKAPNTSSTIVSKSISKNGGKVIYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYNEVFNDQISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
>NC_017349.1|WP_001145730.1|873338_874388_-|site-specific-integrase
MPVYKDDNTGKWYFSIRYKDVYGNNKRKMQRGFSTKREAKSAEAIFLNDVNEGYSDSKTFDYVFHHYLENSDLRPKTKRRKQNEYHKHFKAKFGHIKMNKITQNQCQEFRKYLIENVASTNSARTIWSGFKVVINYAKKYFGLRTDPTISIKPIPRVKPKPKFMMREEFEERIKDIEEQDYRELFTLMFYTGLRIGEAMALVWTDYNKYKKEISINKTMDISNRTIYPRPKTDSSEDIVPLPKFINTMLTERHQREKELNKYFDERSYFIFGGMAPKHYSHVQKKFQKAFPHYNIHALRHSYASYLANNGVDIFVLQSLMRHAQITETMGTYSHLYTQKKHDAIAIFDK
>NC_017349.1|WP_000143212.1|874499_874700_+|excisionase
MTFKNNHNFNELVLTNEDIRILKNVLEDAVSVYDEYSVCNEESDFAYCLLRDLYTLDSLAISSNNV
>NC_017349.1|WP_000391592.1|874636_875542_-|hypothetical-protein
MEEKQYLWRYNDIEKRMNELHKKYKELVDIFFGDVIDKNTGYFPFYSGIKYSYADLNISFYRGLIYIHGGSEGMQAKKINISVDDVLKRTERSFEKLSEYIKSTFIFEKVIHDFQMFNLSDLASIYNDDAIAHYYFETHSDLYLSDKSTKIYRTPNSLLENANDLPASLRKYTQLLETVNDKDFETHIVEAYDCFMSEKRLATSLLLGRALELMCRLILNKFDKDIIKQTPDYKRNIRTFLNEMENNDLIEEHLKHSVKAAIEHRNSIMHGIKIEEYNSIIQTLFDEIAKLSNVYKSLNKQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_2

1255695-1255780

Unclear

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017349_2

>merge|NC_017349|2|1255695-1255780|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTATAATAATGTGCAAGTTGG

>NC_017349|2|1|1255695-1255780|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTATAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_000181404.1\|1255033_1255384_+\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NC_017349.1\|WP_000268754.1\|1253227_1253503_+\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NC_017349.1\|WP_000915251.1\|1255853_1258460_-\|lipoteichoic-acid-specific-glycosyltransferase-YfhO	unknown	unknown	gnl\|CDD\|226888
NC_017349.1\|WP_000863473.1\|1251425_1252793_+\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NC_017349.1\|WP_000195254.1\|1267859_1269167_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NC_017349.1\|WP_001261984.1\|1253690_1254194_+\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NC_017349.1\|WP_000687336.1\|1254193_1254931_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NC_017349.1\|WP_001041674.1\|1262926_1263139_+\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	unknown
NC_017349.1\|WP_000672856.1\|1263166_1264411_+\|FemA/FemB-family-glycyltransferase-FmhC	unknown	unknown	gnl\|CDD\|367067
NC_017349.1\|WP_001020801.1\|1260604_1261771_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NC_017349.1\|WP_000620182.1\|1264582_1265455_+\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NC_017349.1\|WP_000531320.1\|1251067_1251400_+\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NC_017349.1\|WP_000176398.1\|1259728_1260496_+\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|260003
NC_017349.1\|WP_000007680.1\|1249830_1251081_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_017349.1\|WP_078064619.1\|1265628_1267704_+\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|235516
NC_017349.1\|WP_000426914.1\|1245037_1245271_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NC_017349.1\|WP_000110253.1\|1261792_1262701_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NC_017349.1\|WP_000236718.1\|1258860_1259745_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NC_017349.1\|WP_000043237.1\|1245386_1246118_+\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NC_017349.1\|WP_000262687.1\|1246264_1249831_+\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_000181404.1\|1255033_1255384_+\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
NC_017349.1\|WP_000268754.1\|1253227_1253503_+\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
NC_017349.1\|WP_000915251.1\|1255853_1258460_-\|lipoteichoic-acid-specific-glycosyltransferase-YfhO	gnl\|CDD\|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0
NC_017349.1\|WP_000863473.1\|1251425_1252793_+\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NC_017349.1\|WP_000195254.1\|1267859_1269167_+\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NC_017349.1\|WP_001261984.1\|1253690_1254194_+\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	2.95538e-68
NC_017349.1\|WP_000687336.1\|1254193_1254931_+\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.84183e-164
NC_017349.1\|WP_000672856.1\|1263166_1264411_+\|FemA/FemB-family-glycyltransferase-FmhC	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NC_017349.1\|WP_001020801.1\|1260604_1261771_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NC_017349.1\|WP_000620182.1\|1264582_1265455_+\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	4.08676e-102
NC_017349.1\|WP_000531320.1\|1251067_1251400_+\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
NC_017349.1\|WP_000176398.1\|1259728_1260496_+\|ribonuclease-HII	gnl\|CDD\|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	1.13194e-95
NC_017349.1\|WP_000007680.1\|1249830_1251081_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NC_017349.1\|WP_078064619.1\|1265628_1267704_+\|type-I-DNA-topoisomerase	gnl\|CDD\|235516	PRK05582, PRK05582, type I DNA topoisomerase.	0
NC_017349.1\|WP_000426914.1\|1245037_1245271_+\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NC_017349.1\|WP_000110253.1\|1261792_1262701_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NC_017349.1\|WP_000236718.1\|1258860_1259745_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	3.51627e-158
NC_017349.1\|WP_000043237.1\|1245386_1246118_+\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
NC_017349.1\|WP_000262687.1\|1246264_1249831_+\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0

>NC_017349.1|WP_000181404.1|1255033_1255384_+|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR
>NC_017349.1|WP_000687336.1|1254193_1254931_+|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTKQTRVILMCPQGEPFSHQKAVELSKADHMVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>NC_017349.1|WP_001261984.1|1253690_1254194_+|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDIENKKIIITPMKGLLD
>NC_017349.1|WP_000268754.1|1253227_1253503_+|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>NC_017349.1|WP_000863473.1|1251425_1252793_+|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTKLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSIQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>NC_017349.1|WP_000531320.1|1251067_1251400_+|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>NC_017349.1|WP_000007680.1|1249830_1251081_+|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSEGSMQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGAK
>NC_017349.1|WP_000262687.1|1246264_1249831_+|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLIELLENISNEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQSQQTKHQLNDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEATLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>NC_017349.1|WP_000043237.1|1245386_1246118_+|ribonuclease-III
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>NC_017349.1|WP_000426914.1|1245037_1245271_+|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
>NC_017349.1|WP_000915251.1|1255853_1258460_-|lipoteichoic-acid-specific-glycosyltransferase-YfhO
MLKKWLNSNVKQFLVITFISVILTLILFSTHIYDYIVNGTVFSGSGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLLIKIGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGMSTVVIYFNFTWSFYGNLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQAIIIGCYYLYRLIFTYKYDIVSRTQKLICVISATVLSVLSSVFGLFTGISAFLENDRKQNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWVLFIGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSIIALLYVLLSPTHPLALIVGIILLMVLAVILKFSLWRYKKLTVAILVLIVMIQQIVILDNNKNMAIKPYQQSLSTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFIYHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRVNHDDNLPYGFKINSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAMLQGIVSNNTKDVNTHFKANKNLLSDSTIKLNSAAWQSPTKHLLQVKQNNGGLTVQLPKSVSNQFKDLYFEMDLELLSPDKAHDVKVNEYTQERNKLTYKYRRFVKPVTIRIKASDRIRLSLPKGKYRVNLKGIYGEDYTTLKDASNSLEAVKVSKTKQGYTITKNKNSSGYIVLPTAYNQGMQATSGDQSLKVEQVNGVMTGIKAPKNITKIQLSYTPPYYYLLITITIFGIICSIIFTRWARQK
>NC_017349.1|WP_000236718.1|1258860_1259745_+|ribosome-biogenesis-GTPase-YlqF
MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMIDEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIKATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQWIKVGNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQNDLARLKAHYKIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNYCFDIFKDMTEELANDANN
>NC_017349.1|WP_000176398.1|1259728_1260496_+|ribonuclease-HII
MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKALEKEQALKEKYVEMTYFENEILKENPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPVTKRLELNEALKNEVTAFAFGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
>NC_017349.1|WP_001020801.1|1260604_1261771_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
>NC_017349.1|WP_000110253.1|1261792_1262701_+|succinate--CoA-ligase-subunit-alpha
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYESLLTVNK
>NC_017349.1|WP_001041674.1|1262926_1263139_+|YSIRK-type-signal-peptide-containing-protein
MNKQQSKVRYSIRKVSIGTFLNGDYDGKLMKFQSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA
>NC_017349.1|WP_000672856.1|1263166_1264411_+|FemA/FemB-family-glycyltransferase-FmhC
MKFSTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGVKDDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGVFILVDPYLIENLRDANGRIIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVLDLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHFMNEDYFKRMQEIYKDKAMLKIACIDLNEYQDKLKIQLLKIENEMMTVNRALNENPNSKKNKSKLNQLNMQLSSINNRISKTEELILEDGPVLDLAAALFICTDDEVYYLSSGSNPKYNQYMGAYHLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEELIGDFIKPVRPILYKFAKLIYKV
>NC_017349.1|WP_000620182.1|1264582_1265455_+|DNA-protecting-protein-DprA
MIRLFLLKLYWAHFSTKQIHQFLMAYPNVIKEGGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDTEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
>NC_017349.1|WP_078064619.1|1265628_1267704_+|type-I-DNA-topoisomerase
MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVESKKGKTTQVICSNCDYKEAAQK
>NC_017349.1|WP_000195254.1|1267859_1269167_+|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_3

1642898-1642984

Orphan

Consensus_repeat	Method
TTCTCTGTGTTGGGGCCCACACCCCAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017349_3

>merge|NC_017349|3|1642898-1642984|CRISPRCasFinder
TTCTCTGTGTTGGGGCCCACACCCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCACCCCAACTT

>NC_017349|3|2|1642898-1642984|CRISPRCasFinder
TTCTCTGTGTTGGGGCCCACACCCCAACT	CGCATTGCCTGTAGAATTTCTTTTCGAAA
TTCTCTGTGTTGGGGCCCCACCCCAACTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_078064626.1\|1649426_1650113_-\|ComEA-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|224472
NC_017349.1\|WP_000725161.1\|1651799_1652369_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273101
NC_017349.1\|WP_001104616.1\|1635515_1636454_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NC_017349.1\|WP_000048060.1\|1632939_1633116_-\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NC_017349.1\|WP_001274017.1\|1645340_1645592_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
NC_017349.1\|WP_000182221.1\|1639633_1640260_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237622
NC_017349.1\|WP_000108667.1\|1633408_1634755_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694
NC_017349.1\|WP_000627146.1\|1640291_1641269_-\|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl\|CDD\|273017
NC_017349.1\|WP_001119021.1\|1636457_1637597_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237656
NC_017349.1\|WP_041201403.1\|1646667_1648869_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|225212
NC_017349.1\|WP_001282572.1\|1645636_1646611_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511
NC_017349.1\|WP_000218110.1\|1641368_1642493_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NC_017349.1\|WP_001019324.1\|1651225_1651810_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224627
NC_017349.1\|WP_001190122.1\|1634761_1635514_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
NC_017349.1\|WP_041201589.1\|1632012_1632696_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223961
NC_017349.1\|WP_000034714.1\|1637732_1639565_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NC_017349.1\|WP_000439693.1\|1648873_1649335_-\|ComE-operon-protein-2	unknown	unknown	gnl\|CDD\|131622
NC_017349.1\|WP_000368338.1\|1643171_1644995_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NC_017349.1\|WP_000084829.1\|1650152_1650869_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_017349.1\|WP_001088019.1\|1650871_1651225_-\|ribosome-silencing-factor	unknown	unknown	gnl\|CDD\|223870

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_078064626.1\|1649426_1650113_-\|ComEA-family-DNA-binding-protein	gnl\|CDD\|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	1.80317e-31
NC_017349.1\|WP_000725161.1\|1651799_1652369_-\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	gnl\|CDD\|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	2.03869e-76
NC_017349.1\|WP_001104616.1\|1635515_1636454_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	1.66946e-133
NC_017349.1\|WP_000048060.1\|1632939_1633116_-\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
NC_017349.1\|WP_001274017.1\|1645340_1645592_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.42889e-17
NC_017349.1\|WP_000182221.1\|1639633_1640260_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.30081e-81
NC_017349.1\|WP_000108667.1\|1633408_1634755_-\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0
NC_017349.1\|WP_000627146.1\|1640291_1641269_-\|heat-inducible-transcription-repressor-HrcA	gnl\|CDD\|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	5.43412e-119
NC_017349.1\|WP_001119021.1\|1636457_1637597_-\|molecular-chaperone-DnaJ	gnl\|CDD\|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0
NC_017349.1\|WP_041201403.1\|1646667_1648869_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	3.28961e-90
NC_017349.1\|WP_001282572.1\|1645636_1646611_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	6.13705e-105
NC_017349.1\|WP_000218110.1\|1641368_1642493_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NC_017349.1\|WP_001019324.1\|1651225_1651810_-\|HD-domain-containing-protein	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	2.21948e-80
NC_017349.1\|WP_001190122.1\|1634761_1635514_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.2336e-91
NC_017349.1\|WP_041201589.1\|1632012_1632696_-\|hypothetical-protein	gnl\|CDD\|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	7.52459e-63
NC_017349.1\|WP_000034714.1\|1637732_1639565_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NC_017349.1\|WP_000439693.1\|1648873_1649335_-\|ComE-operon-protein-2	gnl\|CDD\|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
NC_017349.1\|WP_000368338.1\|1643171_1644995_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NC_017349.1\|WP_000084829.1\|1650152_1650869_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	9.9222e-16
NC_017349.1\|WP_001088019.1\|1650871_1651225_-\|ribosome-silencing-factor	gnl\|CDD\|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	1.84249e-46

>NC_017349.1|WP_000218110.1|1641368_1642493_-|oxygen-independent-coproporphyrinogen-III-oxidase
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMEIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSRRFKKKFDQSIESVFGQTINNLKEKKLIVEKNDAIALTNRGKVIGNEVFEAFLIND
>NC_017349.1|WP_000627146.1|1640291_1641269_-|heat-inducible-transcription-repressor-HrcA
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDVLNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>NC_017349.1|WP_000182221.1|1639633_1640260_-|nucleotide-exchange-factor-GrpE
MTNKDESVEKNTESTVEETNVKQNIDDSVEQTEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>NC_017349.1|WP_000034714.1|1637732_1639565_-|molecular-chaperone-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEDKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>NC_017349.1|WP_001119021.1|1636457_1637597_-|molecular-chaperone-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>NC_017349.1|WP_001104616.1|1635515_1636454_-|50S-ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQRIKDELLNLDELDQQNVQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>NC_017349.1|WP_001190122.1|1634761_1635514_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEGKVAKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSAISYEKELMG
>NC_017349.1|WP_000108667.1|1633408_1634755_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>NC_017349.1|WP_000048060.1|1632939_1633116_-|30S-ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>NC_017349.1|WP_041201589.1|1632012_1632696_-|hypothetical-protein
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITISITTLGDNLVFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD
>NC_017349.1|WP_000368338.1|1643171_1644995_-|elongation-factor-4
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>NC_017349.1|WP_001274017.1|1645340_1645592_+|30S-ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>NC_017349.1|WP_001282572.1|1645636_1646611_-|DNA-polymerase-III-subunit-delta
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKSPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTLGVHPYRVKLALGQVRHYQLDELLNIIDACAETDYKLKSSYMDKQLILELFILSL
>NC_017349.1|WP_041201403.1|1646667_1648869_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MLYVALSMIVGVLWNSSKVLSTFLFILLLYIAYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEIYPFFLTNKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSSIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTSLNYLADLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>NC_017349.1|WP_000439693.1|1648873_1649335_-|ComE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>NC_017349.1|WP_078064626.1|1649426_1650113_-|ComEA-family-DNA-binding-protein
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLSDQKMIFIPHKGQKNVEPQIGVNSVHVKNGNTNNTKVDLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT
>NC_017349.1|WP_000084829.1|1650152_1650869_-|class-I-SAM-dependent-methyltransferase
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDEHNEDAERLFFIAKK
>NC_017349.1|WP_001088019.1|1650871_1651225_-|ribosome-silencing-factor
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGCNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>NC_017349.1|WP_001019324.1|1651225_1651810_-|HD-domain-containing-protein
MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>NC_017349.1|WP_000725161.1|1651799_1652369_-|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHHDFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVDNAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_4

1926235-1926317

Orphan

Consensus_repeat	Method
CAACATAGTGAAATTGGATCCTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017349_4

>merge|NC_017349|4|1926235-1926317|CRISPRCasFinder
CAACATAGTGAAATTGGATCCTCAATTTCTACAGACGATGCAAGTTGGGGAAACGGCCCCAACATAGTGAAATCGGATCCTCA

>NC_017349|4|3|1926235-1926317|CRISPRCasFinder
CAACATAGTGAAATTGGATCCTCA	ATTTCTACAGACGATGCAAGTTGGGGAAACGGCCC
CAACATAGTGAAATCGGATCCTCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_000116236.1\|1923907_1925293_-\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NC_017349.1\|WP_000669377.1\|1922636_1923458_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NC_017349.1\|WP_000063555.1\|1931750_1932812_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NC_017349.1\|WP_001045133.1\|1920716_1921340_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_017349.1\|WP_001251219.1\|1926809_1927409_-\|glucosamine-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|223440
NC_017349.1\|WP_000901023.1\|1925488_1925884_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000375864.1\|1919896_1920361_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NC_017349.1\|WP_041201594.1\|1929320_1930043_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_017349.1\|WP_000939521.1\|1943180_1943636_-\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|224146
NC_017349.1\|WP_000869461.1\|1942224_1943175_-\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
NC_017349.1\|WP_000649902.1\|1930035_1931493_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NC_017349.1\|WP_000238227.1\|1916206_1917403_-\|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl\|CDD\|223497
NC_017349.1\|WP_014532656.1\|1917699_1917798_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000290301.1\|1918180_1918525_-\|YlbF/YmcA-family-competence-regulator	unknown	unknown	gnl\|CDD\|237467
NC_017349.1\|WP_000181394.1\|1927567_1928038_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|223297
NC_017349.1\|WP_000031108.1\|1926632_1926785_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000437964.1\|1921361_1922474_-\|GAF-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NC_017349.1\|WP_000992515.1\|1918593_1919718_-\|DUF445-domain-containing-protein	unknown	unknown	gnl\|CDD\|226834
NC_017349.1\|WP_000379981.1\|1928042_1929170_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	unknown	unknown	gnl\|CDD\|272993
NC_017349.1\|WP_000110011.1\|1941681_1942128_-\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_000116236.1\|1923907_1925293_-\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NC_017349.1\|WP_000669377.1\|1922636_1923458_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	2.45338e-78
NC_017349.1\|WP_000063555.1\|1931750_1932812_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.23611e-122
NC_017349.1\|WP_001045133.1\|1920716_1921340_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.11819e-78
NC_017349.1\|WP_001251219.1\|1926809_1927409_-\|glucosamine-6-phosphate-isomerase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
NC_017349.1\|WP_000375864.1\|1919896_1920361_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	5.18868e-15
NC_017349.1\|WP_041201594.1\|1929320_1930043_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.80093e-151
NC_017349.1\|WP_000939521.1\|1943180_1943636_-\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.44283e-68
NC_017349.1\|WP_000869461.1\|1942224_1943175_-\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	3.27188e-134
NC_017349.1\|WP_000649902.1\|1930035_1931493_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.83682e-98
NC_017349.1\|WP_000238227.1\|1916206_1917403_-\|exonuclease-SbcCD-subunit-D	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	7.33172e-64
NC_017349.1\|WP_000290301.1\|1918180_1918525_-\|YlbF/YmcA-family-competence-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	1.19759e-37
NC_017349.1\|WP_000181394.1\|1927567_1928038_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
NC_017349.1\|WP_000437964.1\|1921361_1922474_-\|GAF-domain-containing-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.33912e-56
NC_017349.1\|WP_000992515.1\|1918593_1919718_-\|DUF445-domain-containing-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	1.06674e-164
NC_017349.1\|WP_000379981.1\|1928042_1929170_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	1.12653e-179
NC_017349.1\|WP_000110011.1\|1941681_1942128_-\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56

>NC_017349.1|WP_000901023.1|1925488_1925884_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>NC_017349.1|WP_000116236.1|1923907_1925293_-|class-II-fumarate-hydratase
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHQSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>NC_017349.1|WP_000669377.1|1922636_1923458_+|RluA-family-pseudouridine-synthase
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTIDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>NC_017349.1|WP_000437964.1|1921361_1922474_-|GAF-domain-containing-sensor-histidine-kinase
MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGMSNEAIAKQAFKTIEETSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVIFHSQPTKGTQIQFTIPIK
>NC_017349.1|WP_001045133.1|1920716_1921340_-|response-regulator-transcription-factor
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI
>NC_017349.1|WP_000375864.1|1919896_1920361_-|helix-turn-helix-transcriptional-regulator
MDRQSFTDLIQTKFKMVRIEAGYTQDTMAQTIGLSKKTLVQIEKERVLPNWTTCISICALFRDSEVLNSTFGCDPLEIVQTISRNHCAYPNHAPTSDIYWNNIETRNGYILQSNKVSNIYRVLNPDNQPIFGTSKMREAETYFNRNAKEELVHI
>NC_017349.1|WP_000992515.1|1918593_1919718_-|DUF445-domain-containing-protein
MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVPFTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKLTKDQLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYAKHQNQTIASLLPNQLVTFLDQHVDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLIGMLQMFMTKESIADRIQQELIRLTSHPKARTIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYVTTYASKQANKPVVTLMPQFVDYLEGQLSSKLANLIIEQLSIHLSTIMKKVDLRGLIEEQINTFDLDYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV
>NC_017349.1|WP_000290301.1|1918180_1918525_-|YlbF/YmcA-family-competence-regulator
MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDEFRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQIIVKPLDEIYAD
>NC_017349.1|WP_014532656.1|1917699_1917798_-|hypothetical-protein
MSVGSLVVLTTTEIAFPTEIFEKNQRTLQIKF
>NC_017349.1|WP_000238227.1|1916206_1917403_-|exonuclease-SbcCD-subunit-D
MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDIALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKISSNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHIGVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGRHFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQVREEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDESPLVNEFSAELLVDQTVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMRGEQNDN
>NC_017349.1|WP_000031108.1|1926632_1926785_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>NC_017349.1|WP_001251219.1|1926809_1927409_-|glucosamine-6-phosphate-isomerase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>NC_017349.1|WP_000181394.1|1927567_1928038_-|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>NC_017349.1|WP_000379981.1|1928042_1929170_-|tRNA-epoxyqueuosine(34)-reductase-QueG
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVRNEMIKGLDTRRE
>NC_017349.1|WP_041201594.1|1929320_1930043_-|amino-acid-ABC-transporter-ATP-binding-protein
MIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDELTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>NC_017349.1|WP_000649902.1|1930035_1931493_-|ABC-transporter-permease-subunit
MKCLIRFILVLGLLISSAMVYINPTAHAEQDQAWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQVNKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD
>NC_017349.1|WP_000063555.1|1931750_1932812_-|PTS-transporter-subunit-IIC
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTELNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>NC_017349.1|WP_000110011.1|1941681_1942128_-|peroxide-responsive-transcriptional-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>NC_017349.1|WP_000869461.1|1942224_1943175_-|2-hydroxyacid-dehydrogenase
MKVVGLNRMREVETELQQRFSDVDFKFYKKASEIPESDLANLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATKTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEPLLIEILKSRVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
>NC_017349.1|WP_000939521.1|1943180_1943636_-|thioredoxin-dependent-thiol-peroxidase
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_5

2161288-2161383

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTTATGCAG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_017349_5

>merge|NC_017349|5|2161288-2161383|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGCAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTAAGGGGCTCTTATGCAG

>NC_017349|5|4|2161288-2161383|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAG	TTGATGCGCAGCATCCAACTGTGTTCCTCTATTTTT
CAACTTTAGTTGTAAGGGGCTCTTATGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_000070865.1\|2152598_2153042_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NC_017349.1\|WP_000083811.1\|2166144_2167683_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NC_017349.1\|WP_000808817.1\|2156159_2156390_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_001123304.1\|2153241_2153655_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NC_017349.1\|WP_000220901.1\|2161479_2161572_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_001127965.1\|2156420_2157359_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NC_017349.1\|WP_000334471.1\|2163658_2165464_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_017349.1\|WP_000521495.1\|2179450_2180806_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NC_017349.1\|WP_000160304.1\|2151767_2152478_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NC_017349.1\|WP_000908173.1\|2162644_2163427_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NC_017349.1\|WP_000495693.1\|2160179_2161271_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000019737.1\|2158933_2159914_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NC_017349.1\|WP_001024100.1\|2157794_2158460_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NC_017349.1\|WP_000927347.1\|2167717_2169850_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_017349.1\|WP_001292152.1\|2169861_2170296_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NC_017349.1\|WP_000370938.1\|2161719_2162577_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NC_017349.1\|WP_000003759.1\|2158611_2158932_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_017349.1\|WP_000648723.1\|2170295_2171402_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NC_017349.1\|WP_000123402.1\|2154112_2155486_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NC_017349.1\|WP_001048279.1\|2171720_2179172_-\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_000070865.1\|2152598_2153042_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.87929e-68
NC_017349.1\|WP_000083811.1\|2166144_2167683_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NC_017349.1\|WP_001048279.1\|2171720_2179172_-\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	9.1229e-109
NC_017349.1\|WP_001123304.1\|2153241_2153655_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	1.63507e-44
NC_017349.1\|WP_000123402.1\|2154112_2155486_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NC_017349.1\|WP_000334471.1\|2163658_2165464_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_017349.1\|WP_000521495.1\|2179450_2180806_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NC_017349.1\|WP_000160304.1\|2151767_2152478_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NC_017349.1\|WP_001127965.1\|2156420_2157359_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	3.98978e-128
NC_017349.1\|WP_000019737.1\|2158933_2159914_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	5.69522e-109
NC_017349.1\|WP_001024100.1\|2157794_2158460_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.60938e-47
NC_017349.1\|WP_000927347.1\|2167717_2169850_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.74041e-68
NC_017349.1\|WP_001292152.1\|2169861_2170296_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	1.31504e-61
NC_017349.1\|WP_000370938.1\|2161719_2162577_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.26718e-59
NC_017349.1\|WP_000003759.1\|2158611_2158932_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NC_017349.1\|WP_000648723.1\|2170295_2171402_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_017349.1\|WP_000908173.1\|2162644_2163427_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	3.18102e-105

>NC_017349.1|WP_000495693.1|2160179_2161271_+|hypothetical-protein
MFTYFKSALKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQNIAIYSQFGQKPPGDVYLKVIAVLLIAAIVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGIYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLIDNTTKTMTSDKPEDNQPK
>NC_017349.1|WP_000019737.1|2158933_2159914_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFLISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWSITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHQAHHHAHVH
>NC_017349.1|WP_000003759.1|2158611_2158932_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NC_017349.1|WP_001024100.1|2157794_2158460_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NC_017349.1|WP_001127965.1|2156420_2157359_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHKNGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NC_017349.1|WP_000808817.1|2156159_2156390_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NC_017349.1|WP_000123402.1|2154112_2155486_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NC_017349.1|WP_001123304.1|2153241_2153655_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLGIALWLVPKPVRNFGYRMVANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NC_017349.1|WP_000070865.1|2152598_2153042_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NC_017349.1|WP_000160304.1|2151767_2152478_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NC_017349.1|WP_000220901.1|2161479_2161572_+|hypothetical-protein
MTYGSIIAIVCALFVIFFTPYMEKNNKKKK
>NC_017349.1|WP_000370938.1|2161719_2162577_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPEDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSYLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NC_017349.1|WP_000908173.1|2162644_2163427_-|ABC-transporter-ATP-binding-protein
MLIQLDKVGRMKQGKTILKNISWQINGGDKWILYGLNGAGKTTLLNILNAYEPATTGYVNLFGKMPGKVGYSAETVRRHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEIRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKKVAVQRWNNRFSMAMLE
>NC_017349.1|WP_000334471.1|2163658_2165464_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDTLAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVTLQLISYYAALHRDLDVDKPRNLAKSVTVE
>NC_017349.1|WP_000083811.1|2166144_2167683_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIVGFKVLAPIMKFIMYILSVAVESLVHAHLLPVVSILVEPAKILFLNNAINHGVFTPLGTDQAAKVGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKTPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NC_017349.1|WP_000927347.1|2167717_2169850_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGEDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIASPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHIETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLALPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NC_017349.1|WP_001292152.1|2169861_2170296_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKYREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NC_017349.1|WP_000648723.1|2170295_2171402_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NC_017349.1|WP_001048279.1|2171720_2179172_-|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPTAQPAAPANQGQPAAQPAAQPANQGGQANPAGGAAQPNTQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPANQTQPANAPAVAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKVDQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQNANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADNILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDAKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTAQGVTTEKDNGIAVLDQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTAPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEISKIENITDSTQTKMDAYNEVKQAATARKAQNATVSNTTNEEVAEADAAVEAAQKQGLHDILVVKSKQEVAETKSKVLDKINAIQTHAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKQAAYTELDTKKQEARTNLDAANSNSEVATAKDNGITAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANTDIDNAAANTDVDNAKTTNEATIAAITPDANVKPTAKQAIADKVQAQETAIDANNGATTEEKATAKQQVQTEKTTADTAIDGAHSNAEVEAAKNAEIAKIEAIQPATTTKDDAKQAITTKANERKTAIAQTQDITAEEIAAANANVDNAVTQANSNIEAANSQNDVEQAKTTGETSIDQVTPTVNKKATARNEITTILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQVAQTSVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADVQGITADTTIKDVAKDELATKAKEQKALIAQTADATTEEKEQANQQVDAELTQGNQNIENAQSIDDVNTAKDNAIQAIDPILASTDVKTNARAELLTEMQNKITEILSDNTTTNEEKGKDIEPVRATYEEGLNNINTANTTGDVTTAKDTAVQKVQQLHANPVKKPAGKSALDQAAADRKTQIEQTPNASQQEINDAKQEVDAALNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIADAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKETATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALESINNGVDNGDVDDALTQGKAAIDAIQVDATVKPKANQVIDAKAEETKESIDQSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIRGVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPNANDTNSGSDNNDATANSNANATPENTGQPNVTESTDNANADTSSTTTNNQNDAATGETTATSANSSAIDDANDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPATETDNATPAESTTNNNSTTTATNENAPTESTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGMVVQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPKVSSNTSKDKEGSTTNQTDAEQLKSETNVASNEADKSEGNIDTDVSNKPSTSKPSEAKDKATSTEDSQKADMATADTKDNQAAIGATADVNNKATQNDGANASPATVSKGSNSANQDMLKVTNTDKHQAKATSAQQGKVNRPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKNQQTEE
>NC_017349.1|WP_000521495.1|2179450_2180806_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_6

2273464-2273548

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017349_6

>merge|NC_017349|6|2273464-2273548|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGTCTTT

>NC_017349|6|5|2273464-2273548|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	TGTCAGCTTCTGTGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGTCTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_001566779.1\|2269823_2270075_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000503815.1\|2278431_2278938_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NC_017349.1\|WP_001161080.1\|2264381_2264699_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000413855.1\|2268169_2269435_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NC_017349.1\|WP_000866971.1\|2275432_2275666_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NC_017349.1\|WP_000808500.1\|2275671_2276118_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NC_017349.1\|WP_000184419.1\|2271426_2272638_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NC_017349.1\|WP_000066900.1\|2272739_2273090_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NC_017349.1\|WP_000259726.1\|2276613_2277873_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NC_017349.1\|WP_041201470.1\|2273784_2274807_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NC_017349.1\|WP_000051210.1\|2263971_2264136_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000592325.1\|2264885_2268053_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_017349.1\|WP_000643981.1\|2274826_2275426_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NC_017349.1\|WP_000913006.1\|2280141_2280747_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NC_017349.1\|WP_000600965.1\|2270066_2270831_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NC_017349.1\|WP_000602937.1\|2276131_2276617_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NC_017349.1\|WP_000076928.1\|2278968_2279973_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NC_017349.1\|WP_000951070.1\|2270993_2271434_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NC_017349.1\|WP_031927354.1\|2273215_2273386_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000134534.1\|2277935_2278430_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_000503815.1\|2278431_2278938_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	8.15568e-65
NC_017349.1\|WP_000600965.1\|2270066_2270831_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	8.12814e-39
NC_017349.1\|WP_000413855.1\|2268169_2269435_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	8.95714e-143
NC_017349.1\|WP_000866971.1\|2275432_2275666_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NC_017349.1\|WP_000184419.1\|2271426_2272638_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.27961e-72
NC_017349.1\|WP_000066900.1\|2272739_2273090_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NC_017349.1\|WP_000259726.1\|2276613_2277873_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	9.192e-158
NC_017349.1\|WP_041201470.1\|2273784_2274807_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.30726e-164
NC_017349.1\|WP_000592325.1\|2264885_2268053_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_017349.1\|WP_000602937.1\|2276131_2276617_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50
NC_017349.1\|WP_000913006.1\|2280141_2280747_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.03488e-114
NC_017349.1\|WP_000808500.1\|2275671_2276118_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NC_017349.1\|WP_000643981.1\|2274826_2275426_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	1.09736e-66
NC_017349.1\|WP_000076928.1\|2278968_2279973_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	1.8332e-130
NC_017349.1\|WP_000951070.1\|2270993_2271434_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.15651e-14
NC_017349.1\|WP_000134534.1\|2277935_2278430_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.70933e-97

>NC_017349.1|WP_031927354.1|2273215_2273386_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDTNVKEPLKIYYVVILKSGIEMIFS
>NC_017349.1|WP_000066900.1|2272739_2273090_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NC_017349.1|WP_000184419.1|2271426_2272638_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFLVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NC_017349.1|WP_000951070.1|2270993_2271434_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITLYRPYLKLAEPILEKHNIYYGQWLILRDIAKYQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPEGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NC_017349.1|WP_000600965.1|2270066_2270831_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNQSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NC_017349.1|WP_001566779.1|2269823_2270075_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>NC_017349.1|WP_000413855.1|2268169_2269435_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEIQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NC_017349.1|WP_000592325.1|2264885_2268053_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGVTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASASNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSDEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMFKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NC_017349.1|WP_001161080.1|2264381_2264699_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVIFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NC_017349.1|WP_000051210.1|2263971_2264136_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NC_017349.1|WP_041201470.1|2273784_2274807_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDAVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NC_017349.1|WP_000643981.1|2274826_2275426_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYRRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NC_017349.1|WP_000866971.1|2275432_2275666_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NC_017349.1|WP_000808500.1|2275671_2276118_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NC_017349.1|WP_000602937.1|2276131_2276617_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NC_017349.1|WP_000259726.1|2276613_2277873_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NC_017349.1|WP_000134534.1|2277935_2278430_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIYKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>NC_017349.1|WP_000503815.1|2278431_2278938_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITMQVKKWLKEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNDKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NC_017349.1|WP_000076928.1|2278968_2279973_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDVMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSACTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NC_017349.1|WP_000913006.1|2280141_2280747_-|ATP-binding-cassette-domain-containing-protein
MLKINLKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_7

2336305-2336391

Orphan

Consensus_repeat	Method
ATTAGAGCCTCTTATGCAGTTGCTCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017349_7

>merge|NC_017349|7|2336305-2336391|CRISPRCasFinder
ATTAGAGCCTCTTATGCAGTTGCTCAGTCAACTGTATACCTTTTGCCTTTAACTTAAGTTATTAGAGCCTCTTATGCAGTTGCTCAG

>NC_017349|7|6|2336305-2336391|CRISPRCasFinder
ATTAGAGCCTCTTATGCAGTTGCTCAG	TCAACTGTATACCTTTTGCCTTTAACTTAAGTT
ATTAGAGCCTCTTATGCAGTTGCTCAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_000730048.1\|2329961_2330843_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181188
NC_017349.1\|WP_000623445.1\|2340556_2341210_+\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|225167
NC_017349.1\|WP_072491263.1\|2342869_2343055_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000991506.1\|2323934_2325539_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273925
NC_017349.1\|WP_001226816.1\|2333590_2335252_-\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448
NC_017349.1\|WP_000548682.1\|2343038_2344271_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224582
NC_017349.1\|WP_000655867.1\|2339699_2340386_-\|ribose-5-phosphate-isomerase-A	unknown	unknown	gnl\|CDD\|184433
NC_017349.1\|WP_000277977.1\|2337152_2338088_-\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|184317
NC_017349.1\|WP_000451827.1\|2327382_2328678_-\|Na+/H+-antiporter-NhaC-family-protein	unknown	unknown	gnl\|CDD\|224671
NC_017349.1\|WP_000477989.1\|2325868_2326633_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NC_017349.1\|WP_001051556.1\|2326690_2327197_-\|SRPBCC-domain-containing-protein	unknown	unknown	gnl\|CDD\|226353
NC_017349.1\|WP_000634685.1\|2341445_2342465_-\|galactose-mutarotase	unknown	unknown	gnl\|CDD\|185696
NC_017349.1\|WP_000966695.1\|2342494_2342821_-\|YnfA-family-protein	unknown	unknown	gnl\|CDD\|224656
NC_017349.1\|WP_000998761.1\|2332352_2333591_-\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
NC_017349.1\|WP_001185183.1\|2328902_2329475_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000794449.1\|2338377_2339634_+\|CPBP-family-intramembrane-metalloprotease-SdpC	unknown	unknown	gnl\|CDD\|224185
NC_017349.1\|WP_000524825.1\|2344263_2345163_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226631
NC_017349.1\|WP_000691839.1\|2335411_2336296_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_017349.1\|WP_000920235.1\|2336477_2336897_+\|FosB/FosD-family-fosfomycin-resistance-bacillithiol-transferase	unknown	unknown	gnl\|CDD\|179740
NC_017349.1\|WP_000523129.1\|2330953_2332075_-\|M20-peptidase-aminoacylase-family-protein	unknown	unknown	gnl\|CDD\|349919

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_000730048.1\|2329961_2330843_-\|SDR-family-oxidoreductase	gnl\|CDD\|181188	PRK07985, PRK07985, SDR family oxidoreductase.	1.51555e-133
NC_017349.1\|WP_000623445.1\|2340556_2341210_+\|MOSC-domain-containing-protein	gnl\|CDD\|225167	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown].	1.27002e-88
NC_017349.1\|WP_000991506.1\|2323934_2325539_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273925	TIGR02005, PTS-IIBC-alpha, PTS system, alpha-glucoside-specific IIBC component. This model represents a family of fused PTS enzyme II B and C domains. A gene from Clostridium has been partially characterized as a maltose transporter, while genes from Fusobacterium and Klebsiella have been proposed to transport the five non-standard isomers of sucrose. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NC_017349.1\|WP_001226816.1\|2333590_2335252_-\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
NC_017349.1\|WP_000548682.1\|2343038_2344271_-\|ABC-transporter-permease	gnl\|CDD\|224582	COG1668, NatB, ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism].	1.87659e-72
NC_017349.1\|WP_000655867.1\|2339699_2340386_-\|ribose-5-phosphate-isomerase-A	gnl\|CDD\|184433	PRK13978, PRK13978, ribose 5-phosphate isomerase A.	7.0255e-156
NC_017349.1\|WP_000277977.1\|2337152_2338088_-\|formimidoylglutamase	gnl\|CDD\|184317	PRK13774, PRK13774, formimidoylglutamase; Provisional.	0
NC_017349.1\|WP_000794449.1\|2338377_2339634_+\|CPBP-family-intramembrane-metalloprotease-SdpC	gnl\|CDD\|224185	COG1266, COG1266, Predicted metal-dependent membrane protease [General function prediction only].	1.1158e-10
NC_017349.1\|WP_000477989.1\|2325868_2326633_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	3.91257e-62
NC_017349.1\|WP_001051556.1\|2326690_2327197_-\|SRPBCC-domain-containing-protein	gnl\|CDD\|226353	COG3832, COG3832, Uncharacterized conserved protein [Function unknown].	4.34585e-27
NC_017349.1\|WP_000634685.1\|2341445_2342465_-\|galactose-mutarotase	gnl\|CDD\|185696	cd09019, galactose_mutarotase_like, galactose mutarotase_like. Galactose mutarotase catalyzes the conversion of beta-D-galactose to alpha-D-galactose. Beta-D-galactose is produced by the degradation of lactose, a disaccharide composed of beta-D-glucose and beta-D-galactose. This epimerization reaction is the first step in the four-step Leloir pathway, which converts galactose into metabolically important glucose. This epimerization step is followed by the phosophorylation of alpha-D-galactose by galactokinase, an enzyme which can only act on the alpha anomer. A glutamate and a histidine residue of the galactose mutarotase have been shown to be critical for catalysis, the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. Galactose mutarotase is a member of the aldose-1-epimerase superfamily.	9.6517e-99
NC_017349.1\|WP_000966695.1\|2342494_2342821_-\|YnfA-family-protein	gnl\|CDD\|224656	COG1742, COG1742, Uncharacterized conserved protein [Function unknown].	2.59201e-46
NC_017349.1\|WP_000998761.1\|2332352_2333591_-\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
NC_017349.1\|WP_000451827.1\|2327382_2328678_-\|Na+/H+-antiporter-NhaC-family-protein	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	1.10964e-88
NC_017349.1\|WP_000524825.1\|2344263_2345163_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226631	COG4152, COG4152, ABC-type uncharacterized transport system, ATPase component [General function prediction only].	3.54738e-172
NC_017349.1\|WP_000691839.1\|2335411_2336296_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.61438e-49
NC_017349.1\|WP_000920235.1\|2336477_2336897_+\|FosB/FosD-family-fosfomycin-resistance-bacillithiol-transferase	gnl\|CDD\|179740	PRK04101, PRK04101, metallothiol transferase FosB.	6.62319e-93
NC_017349.1\|WP_000523129.1\|2330953_2332075_-\|M20-peptidase-aminoacylase-family-protein	gnl\|CDD\|349919	cd05669, M20_Acy1_YxeP-like, M20 Peptidase aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2. Peptidase M20 family, aminoacyclase-1 YxeP-like subfamily including YxeP, YtnL, YjiB and HipO2, most of which have not been well characterized to date. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as in the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney suggest a role of the enzyme in amino acid metabolism of these organs.	0

>NC_017349.1|WP_000691839.1|2335411_2336296_+|LysR-family-transcriptional-regulator
MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLGYDLFTRSTKDIKITEKGIQFYRYASELVQQYRSTMEKMYDLSVTSEPRIKIGTLESTNQWIANLIRKHHSDYPEQQYRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPLYEESYILLAPKETFKNQNWVDVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETDRFESAVGFVHLGLGYAIIPRFYYQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQVHTFVQQCQDYLYGLLEAL
>NC_017349.1|WP_001226816.1|2333590_2335252_-|urocanate-hydratase
MRKIQAKKGLSIDCKGWEQEAVLRMLYNNLDPEVAERPEDLVVYGGIGKAARNWEAFEAIEKTLRELESDETMLVQSGKPVAVFKTHEEAPRVLISNSVLVPEWANWDHFNELDKKGLIMYGQMTAGSWIYIGSQGIVQGTYETFAELGNQHFNGDLAGTVTLTAGLGGMGGAQPLAITMNHGVAICVDVDETRVDKRIDTKYCDVKTADLDEALKLAEEAKERGEGLSIGLVGNAVDIHQAILEKGFKIDIITDQTSAHDPLNGYVPQGYSVEEAKVLREKDPKKYVELSQASMAKHVELMLEFQKRGAVAFDYGNNIRQVAFNNGVKNAFDFPGFVPAYIRPLFCEGKGPFRFAALSGDPKDIERADEEMRKLFPENEKLLRWLDLAEEKISYQGLPSRIAWLGYGERAKMGLALNRLVRDGEISAPIVIGRDHLDAGSVASPNRETESMKDGSDAVGDWAVLNALINTAAGGSWISFHHGGGVGMGYSLHAGMVVVADGSERAERRLERVLTTDPGMGVARHVDAGYDIAIQTAKEKGIHIPMIDKAGDK
>NC_017349.1|WP_000998761.1|2332352_2333591_-|imidazolonepropionase
MNDLIINHIAELILPRSTDKPLKGKELDELNVVKNGTVVIKDGKIVYAGQHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEILEMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLKVSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETGVFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEKLRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNLQLVMAIAALKLKLSPNEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINHAEKVIKDGKVIVDNTLSFKA
>NC_017349.1|WP_000523129.1|2330953_2332075_-|M20-peptidase-aminoacylase-family-protein
MGLKDQAVAWRRYFHQFPELSDKEFKTTQKIKDILTEHHIRILDLPLATGLVAEVGQGPSCIAVRADIDALPIQELVEQDFKSENEGVMHACGHDIHMASILATAVKLKEIEGTLTGRVKFIFQPAEELGYGAFKIIETHALKDVQAVLGFHNDPSRPVGTFAIKTGAITSAVDRFEFHIKGVGGHAAKPEQCNDPVIVLAQLINSIQSIVSRNLSAFHEAVVTIGQISCGNTWNVIADHAYVQGTVRSFDPVVRKLVETRLQDIADGLAQAYNMKINLNYTHLPGAVMNDEALTHKAIAVAQHVGYKVEMMEQPLTIGEDFSGYSQHFPSVFALIGSHSEYDLHHPQYKPDERILEKVPEYFVEFVKRLLHE
>NC_017349.1|WP_000730048.1|2329961_2330843_-|SDR-family-oxidoreductase
MAAQDPRTKFKTTDYEKQEQEVPGLQSEMTPAPDCGETSYQGHQRLQGYKMLVTGGDSAIGRAAAIAYAKEGADVAINYLPSEEQDAQEVRQVIEESGQKAVLIPGDIRDEQFNYDLVEHAYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNVYPLFWTVQKALEYLKPGASITTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGPKGIRVNCVAPGPFWSPLQISGGQPQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEESSYTTGQVFGVSGGVQID
>NC_017349.1|WP_001185183.1|2328902_2329475_-|hypothetical-protein
MALIVSRAILFLILALAFGIATVFPEQKLPIYIVFTLFVVVAIVSNVWITHQNVKKHIIKFNKRVAYFLGVLSGVFYIGIVIYGATIIGYYNFISFIIFAISIVSITILEIVLGINFKNTPPSNKQLKVISEQSAQQFKVISLILVSVSIVFIFIALMLKWWLLLVISIIVLIIITVAMIVYEKYYTTPD
>NC_017349.1|WP_000451827.1|2327382_2328678_-|Na+/H+-antiporter-NhaC-family-protein
MEVHKKSNAWALFPLLLFVALFLGVGIITGDFTSMPLNVAITITVIVALLMNRKESFAKKVEVFTKGAGHSNIILMMLIFILAGAFSNTAEKMGGVKSTVNLGLSLIPENLIIVGLFVICMFVSISMGTSVGTVAAIAPVGYGFAQATDVPTALAMATVVGGAMFGDNLSMISDTTIAAVRTQHTKMKDKFRVNFKIVLPGAILTIIILYFLTNGISLNHAKNYDYNLIKVVPYILVLVLALLGVNVIIVLIGGTLLAGIIGLIDGSFGWMGLLDAVSKGIISMEDIAMIALLIGGLVGIIQHNGGIEWLLQFVRSKVKSKRGAELGIASLVSVADIATANNTISIIMSGPLAKNIADEYDVDSRKSASILDIFGGCFQGLLPYSPQVISAAGVAGISPLMLFPYSIYPILLGVCGLIAILFNFPKLKKEH
>NC_017349.1|WP_001051556.1|2326690_2327197_-|SRPBCC-domain-containing-protein
MAKFNVENEHVEVEIEKLYKFSPELVYEAWTKKDLLKQWFMTSARTNKEIEADVKEGGKYRIVDQQRNGKVNVIEGIYESLVMDEYVKMTIGMPGLSETQDVIEVEFFERETGGTQMLFYYRSLVEKERRFTNLEYKQKKKEYHDAMVHGFELMFDKMYHVIETSTQQ
>NC_017349.1|WP_000477989.1|2325868_2326633_+|MurR/RpiR-family-transcriptional-regulator
MFLDEHINRNFDKLNDNDLHIAHFINTHIDECKNMKIQDLAQFTHASNATIHRFTRKLGFDGYSDFKSYLKFESNKTHQLPSNSIDSFKQEIDSTFSYLERVDYQLLTEKMHTASTIYLYGTGRAQLNVASEAQRILLTLHNHVIVLHDEHELKMILNKSEPNDLFFIISLSGETHELLEVTNLLQLRQKYFISVTTMKDNTLAQKANYNVYVSSNTFYLTDGTDYSSFISYHIFFETLVRKYNEYLLHNDISN
>NC_017349.1|WP_000991506.1|2323934_2325539_-|PTS-transporter-subunit-EIIC
MNAIKRFGSAMIVPVLMFAFFGIVLGFATLFKNPTIMGSLADQHTFWFKFWSVIESGGWVIFTHMEVVFVVGLPLSLAKKAPGHAALAALMGYLMFNTFINAILTQWPHTFGANLEKGVENVPGLKSIAGIATLDTNILGGIIISAIITWIHNRYYSKRLPEMVGVFQGLTFVVTISFFVMLPLAAITCVIWPTVQHGIGSMQHFIIASGYIGVWLYHFLERVLIPTGLHHFIYAPIEVGPVVVNHGLKAEWLQHLNEFAKSTKPLKEQFPYGFMLQGNGKVFGCLGIALAMYATTPKENRKKVAALLIPATLTAVVVGITEPLEFTFLFIAPYLFVLHAVLAASMDTLMYAFGVVGNMGGGLLDFISTNWLPLGKEHWGTYVAQVVIGLIFVAIYFFLFRFLILKFDIPLPGRKKTEEEVKLFSKQDYKNKKGDSVDSKRASTGNEYEDKAAYYLDGLGGKENIKDVTNCTTRLRLTVYDESKVADTEYFTHQQMAHGLVKSGKSIQVVVGMTVPQVREAFEQMVEDQSSEDK
>NC_017349.1|WP_000920235.1|2336477_2336897_+|FosB/FosD-family-fosfomycin-resistance-bacillithiol-transferase
MLKSINHICFSVRNLNDSIHFYRDILFGKLLLTGKKTAYFKLAGLWIALNEEKDIPRNEIHFSYTHIAFTIDDSEFKYWHQRLKDNNVNILEGRVRDIRDRQSIYFTDPDGHKLELHTGTLENRLNYYKEAKPHMTFYK
>NC_017349.1|WP_000277977.1|2337152_2338088_-|formimidoylglutamase
MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSRPSGVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEELIDTQKEFAMLAAKSIANHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDTRAEQQSTSGTSFRQILEEDENTDYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLSHVSPTIKDMIERFVHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIPSDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK
>NC_017349.1|WP_000794449.1|2338377_2339634_+|CPBP-family-intramembrane-metalloprotease-SdpC
MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSIIGVKHFIFEVTDLAPLIAAIICILVFKYKKVQLAGLKFSISLKVIERLLLALILPLIILIIGMYSFNTFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVGLMYSVFSANTTYGTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLIFLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIVYLTTRRNLEELEPNNYLDHVNDDEETNHTEAEKSSSNIKDAEKTGVATASTVGIAKNDTENTVADEPSIHEGTEKIEAQHHIDNQTESNHDEDHEITLESVESAESVKHAPQSDDLTNDSNEDEIQSLKEPATYKEDRRSSVVIDAEKHIEKTEEQSSDKNK
>NC_017349.1|WP_000655867.1|2339699_2340386_-|ribose-5-phosphate-isomerase-A
MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLIKERGYNITGVCTSNKIAFLAKELGIKICEINDVDHIDLAIDGADEVDPSLNIIKGGGGALFREKVIDEMASRFVVVVDETKMVQYLGETFKLPVEVDKFNWYHILRKIESYADIKVERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVGTQEGVKILEK
>NC_017349.1|WP_000623445.1|2340556_2341210_+|MOSC-domain-containing-protein
MISIHAISTGKIQDLPYSSKRPMRSALDKTKISQTTWLSSTGFTGDEQAYKDHGGPHKAVCGFSKHNYALYQDDLPSLPTHAMFGENLTFDYLDESDVYFGNQYRLGEALIEVSEIREPCWKIQAKYNIPDLVKRMSTSGKTGFYFRVLKQGYVSPNDQLYLIQEAPIEHRLSVQQLNDLYYNDRQNQDMLRYALNNPFLSPTRRDKLQKMYNRTLK
>NC_017349.1|WP_000634685.1|2341445_2342465_-|galactose-mutarotase
MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIVLGNVVEADEFYHSNPFKFGASIGRYSGRIDNAKFKLKGKEYQLEKNNGEHHLHGGCHGLDNKLFDYEIRNEIAQIKVIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVASEDTLFSPTNHVYFNLNRDNNVVDNHRISSNQLDMYVLDERNIVTGDILDLHEVFEDNKIKLSDIFTSQHAQLSQQMTRFGGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFTFNQPDEWDSPFNIYKPHSGFTLETQFLPNDINLYGEKAPSILKAGEVFNSKTSFRIEEKVEND
>NC_017349.1|WP_000966695.1|2342494_2342821_-|YnfA-family-protein
MLYPIFIFILAGLCEIGGGYLIWLWLREGQSSLVGLIGGAILMLYGVIATFQSFPSFGRVYAAYGGVFIIMSLIFAMVVDKQMPDKYDVIGAIICIVGVLVMLLPSRA
>NC_017349.1|WP_072491263.1|2342869_2343055_-|hypothetical-protein
MYLKNKIDESDTHLSYKMMMKACYSYFFIFSYRIMSKKVYNMNVKTNFLKWECEVRRNVNE
>NC_017349.1|WP_000548682.1|2343038_2344271_-|ABC-transporter-permease
MHKFWATFSLTYIKKIKAKSFVIFMIIIAALMIGLSNIDKIINMFDDGPDKIGVAAPNEQIYKVFKQQANTFHSDAKFTKVSIEDAEKEVKKHKLDKAYIIKVNQNRTLQGTIISEKRVSHEDSQKVQALLTAIQTNMVAGELNINKEDLQKLQAQSKVDNKVISNDEVDKVSEGQKIFNYALAYGIIFLMFFIVLNYASQIAMEIASEKTSRVIEMIITSISPIQHIFAKILGVIAVAVTQIILIVLMAVICIFAFDLKDLLQGFNVEMNQLSWQIIIVGIISSIVGIMAYVLLAAILGSLTSRIEDLNQSLMPLTLLGMIAFYIAIFTINNPDGQLALITSYIPFLAPFQLVVRAQTSGLQIHEVILSSLISIVMVAVLIWIAIKTYKDSVLTFERGLFNSMKRVFKK
>NC_017349.1|WP_000524825.1|2344263_2345163_-|ABC-transporter-ATP-binding-protein
MGLVIEHVTKRFGKMTAVNDISLELESGKMLGFLGRNGAGKTTTFRMILGLSEPTEGHITYNGKKLDKTMYNRIGYLPEERGLHGKLTVEEELKYLATLKGMSKTEIQQQISYWLERFDITENRKKRIDSLSKGNQQKIQLLASMLHKPELLILDEPFSGLDPVNVELLKEAVKDLNDWGSTIVYSSHRMEHVEELCDDVCILDKGQLVVSGDINHVRASNGNKKVVIESETTLPDLTHIRGIIHSENMKQGIQLTIENEDVAKDIYQVVAHQGYVKRFQVVEPSLQDIFIEKVGGKDA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_8

2513470-2513754

Orphan

Consensus_repeat	Method
TACNTCTGGTGTNGGTGGNGTTGG	CRT

6 spacers

The CRISPR arrays of NC_017349_8

>merge|NC_017349|8|2513470-2513754|CRT
TTCTTCTTTAGCAGGTGGTACTGGTTTACCAGGTTCAGCTGGTACCTCTGGTGTTGGTGGTACTGGTGTGCCTGGCTCACTTGGTACCTCTGGTGTTGGCGGTGTTGGTGTTGGCGGTGTTTCCGGCTCACCTGGTACCTCTGGTGTCGGTGGCGTTGGTGTTTCCGGCTCACTCGGTACCTCTGGCGTTGGTGGTGTTGGCTTACCTGGCTCACTTGGCACTTCTGGTGTCGGTGGCGTTGGTGTTTCCGGCTCACTTGGTACTTCTGGTGTCGGTGGCGTTGT

>NC_017349|8|1|2513470-2513754|CRT
TTCTTCTTTAGCAGGTGGTACTGG	TTTACCAGGTTCAGCTGG
TACCTCTGGTGTTGGTGGTACTGG	TGTGCCTGGCTCACTTGG
TACCTCTGGTGTTGGCGGTGTTGG	TGTTGGCGGTGTTTCCGGCTCACCTGG
TACCTCTGGTGTCGGTGGCGTTGG	TGTTTCCGGCTCACTCGG
TACCTCTGGCGTTGGTGGTGTTGG	CTTACCTGGCTCACTTGG
CACTTCTGGTGTCGGTGGCGTTGG	TGTTTCCGGCTCACTTGG
TACTTCTGGTGTCGGTGGCGTTGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_000435044.1\|2527681_2528293_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NC_017349.1\|WP_041201531.1\|2499375_2500161_-\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NC_017349.1\|WP_000289133.1\|2521644_2522337_-\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NC_017349.1\|WP_000217719.1\|2508112_2508421_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000721337.1\|2508545_2509412_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NC_017349.1\|WP_014533134.1\|2525857_2527135_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_017349.1\|WP_041201604.1\|2501157_2501931_-\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NC_017349.1\|WP_000841385.1\|2509591_2512558_-\|fibronectin-binding-protein-FnbB	unknown	unknown	gnl\|CDD\|371043
NC_017349.1\|WP_000755954.1\|2505100_2505493_-\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|239517
NC_017349.1\|WP_000581901.1\|2500272_2501046_-\|tandem-type-lipoprotein	unknown	unknown	gnl\|CDD\|367972
NC_017349.1\|WP_000481405.1\|2516829_2518188_-\|gluconate-permease	unknown	unknown	gnl\|CDD\|129873
NC_017349.1\|WP_000876651.1\|2518304_2519858_-\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NC_017349.1\|WP_000074003.1\|2520715_2521480_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NC_017349.1\|WP_000990135.1\|2519881_2520562_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NC_017349.1\|WP_000678769.1\|2507702_2507969_+\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000356888.1\|2505781_2507419_+\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092
NC_017349.1\|WP_001117056.1\|2522567_2522984_-\|DUF2188-domain-containing-protein	unknown	unknown	gnl\|CDD\|227213
NC_017349.1\|WP_041201538.1\|2528301_2528400_-\|hypothetical-protein	unknown	unknown	unknown
NC_017349.1\|WP_000088714.1\|2502237_2505099_-\|DUF3427-domain-containing-protein	unknown	unknown	gnl\|CDD\|223989
NC_017349.1\|WP_014533133.1\|2523122_2524946_-\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|224208

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_000435044.1\|2527681_2528293_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	7.26208e-43
NC_017349.1\|WP_041201531.1\|2499375_2500161_-\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	4.2709e-134
NC_017349.1\|WP_000289133.1\|2521644_2522337_-\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	1.55739e-85
NC_017349.1\|WP_014533133.1\|2523122_2524946_-\|FUSC-family-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	1.00983e-84
NC_017349.1\|WP_000721337.1\|2508545_2509412_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	5.5142e-177
NC_017349.1\|WP_014533134.1\|2525857_2527135_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.03842e-91
NC_017349.1\|WP_041201604.1\|2501157_2501931_-\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	1.78266e-129
NC_017349.1\|WP_000841385.1\|2509591_2512558_-\|fibronectin-binding-protein-FnbB	gnl\|CDD\|371043	pfam10425, SdrG_C_C, C-terminus of bacterial fibrinogen-binding adhesin. This is the C-terminal half of a bacterial fibrinogen-binding adhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin that allows attachment of the bacterium to host tissues via specific binding to the beta-chain of human fibrinogen (Fg). SdrG binds to its ligand with a dynamic "dock, lock, and latch" mechanism which represents a general mode of ligand-binding for structurally related cell wall-anchored proteins in most Gram-positive bacteria. The C-terminal part of SdrG(276-596) is integral to the folding of the immunoglobulin-like whole to create the docking grooves necessary for Fg binding. The domain is associated with families of Cna_B, pfam05738.	1.65452e-34
NC_017349.1\|WP_000088714.1\|2502237_2505099_-\|DUF3427-domain-containing-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	2.58079e-90
NC_017349.1\|WP_000581901.1\|2500272_2501046_-\|tandem-type-lipoprotein	gnl\|CDD\|367972	pfam04507, DUF576, Csa1 family. This family contains several uncharacterized staphylococcal proteins. These proteins have been called conserved staphylococcal antigens (Csa).	2.27481e-126
NC_017349.1\|WP_000481405.1\|2516829_2518188_-\|gluconate-permease	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.12692e-167
NC_017349.1\|WP_000876651.1\|2518304_2519858_-\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NC_017349.1\|WP_000074003.1\|2520715_2521480_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	2.82611e-33
NC_017349.1\|WP_000990135.1\|2519881_2520562_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.38656e-43
NC_017349.1\|WP_000356888.1\|2505781_2507419_+\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NC_017349.1\|WP_001117056.1\|2522567_2522984_-\|DUF2188-domain-containing-protein	gnl\|CDD\|227213	COG4876, COG4876, Uncharacterized protein conserved in bacteria [Function unknown].	1.78015e-61
NC_017349.1\|WP_000755954.1\|2505100_2505493_-\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	7.19499e-57

>NC_017349.1|WP_000841385.1|2509591_2512558_-|fibronectin-binding-protein-FnbB
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNITVEESGNSATESKASETQTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPTTVQAPKVETSRVDLPSEKVADKETTGTQVDTTQQSNASEIKPRMKRSADVAEMAEKEVVGEAKTTGSDVTNKVTVENGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKAGDYFDFTLSDNVETHGISTLRKVPEIKSSTEDKVMANGQVIGERKIRYTFTDYIDNKKDLTAELTLNLFIDPTTVTKQGMEKVEVSLGQNKVSKEFDIKYLDGVKDRMGVTVNGRIDTLNKADGKFSHFAYVKPNNQSLSSVTVTGQVTSGYKQNAKNPTVKVYKHIGSDELAESVYAKLDDANKFEDVTNKVNLSYTGDGGYSLNFNDLDNTKNYVIKYEGEYDQNAKDLNFRTHLSGYHKNYLYSPYYPYYPVQLTWNNGVAFYSNKAQGDGKDKPNDPIIEKSEPIELDIKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGSEGHAEGIVETEEDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTVEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIIDIDFDSVPQIHGFNKHNEIIEEDTNKDKPNYQFGGHNSADFEEDTLPKVSGQNEGQQTIEEDTTPPTPEVPSEPETPMPPTPEVPSEPGEPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPGEPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPGESTPPTPEVPAEPGKPVPPAKEEPKKTSKPVEQGKVVTPVIEINEKVKAVAPTKKAQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNHKA
>NC_017349.1|WP_000721337.1|2508545_2509412_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKELGL
>NC_017349.1|WP_000217719.1|2508112_2508421_+|hypothetical-protein
MTVNIVVSIVFCISMIILGIYVAITKDFTLISFINQTTIADKHKNQIAYIFALCISLSAVFLMSAILCFEYDFIALSFLFLTIALLLIALFYVCFYKITKYP
>NC_017349.1|WP_000678769.1|2507702_2507969_+|hypothetical-protein
MKGSKQILLIMGIISLIVLFVFTLFIMAQYAKHYEQKSDSSNAHTLNSSSAIIEQHTMSNLASLDLYAPVRNITSSRDIHPIYFMTKN
>NC_017349.1|WP_000356888.1|2505781_2507419_+|phospho-sugar-mutase
MDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNTQTNNPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVGYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYQLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS
>NC_017349.1|WP_000755954.1|2505100_2505493_-|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase
MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKCDLIVGDKVITTEHEYDFGIVRLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADIPAVNKIMTEG
>NC_017349.1|WP_000088714.1|2502237_2505099_-|DUF3427-domain-containing-protein
MSRLLNDFNQSLHKGFIDKHISHKGNYTPKLLVNNKNEKVLSTIIDELQKCETFYFSVAFITESGLASLKAQLLDLSNKGVKGKILTSNYLGFNSPKMYGELLKLKNVEVRLTDIAGFHAKGYIFEHKDYSSMVIGSSNLTSNALKVNYEHNVLLSTMKNGDLVDSVKNEFDLLWQNSTPLTQQWINSYKESFEYRSLEKLAEVEQTQMLLADKVKKSVEIVPNLMQAEALRSLKAIRDKAKDKALIISATGTGKTILCALDVREVNPNKFLFIVHNEGILNRAKEEFKKVLPIKNDSDFGLLTGKHRDVDAKYLFATIQTLSRDDNFKQFDEKEFDYIVFDEAHRSAASTYQRVFNYFKPKFMLGMTATPERSDELSIFEMFDYNIAYEIRLQAALESDILCPFHYFGVTDYVHQGIKEDDVTKLRYLTSDERVNYIIQKTDYYGYSGEILQGLIFVSSKKEAYDLADKLSSKGIKSVALTGDDSVNYRQIVIEKLKEGKINYIITVDLFNEGIDIPEVNQVVMLRPTESSIIFIQQLGRGLRKSSNKEYVTVIDFIGNYKTNYLIPIALSGDQSQNKDNYKKFLTNNDSINGVSTINFEEVAKKQIYNSLDAVSLNQNKLILKAYEEVENRLGHMPLLMDFIQQHSIDPSVIFSKFSNYYEFLVRYKKIDALLTENESKNLVFFSRQIAPGLKRIDSLVLEELLKNELTYDELKNKMLNEVKDITEDDIDTSLRILDFSFYNAGIEKIYGSPIIECNERMIRLSDAFTNALSNQTFKIFLEDLIELSKYNNEKYQKGKNGLILYNKYSREDFSKIFNWSKNGSSVIMGYMIRSQEMPIFITYDKHEDISDSTKYEDEFLSQDELKWFTKSNRTLKSKEVQKILSHRAKGIKMYIFVQKKDDDGIYFYYLGTAGYIEGSEKQDKMPNGSNVVTMDLALDKAVRDDIYRYITN
>NC_017349.1|WP_041201604.1|2501157_2501931_-|tandem-type-lipoprotein
MIHSKRLKMCLCLIILSVFIGACGMKKEKSSKDKQIKENFNKTLSLYPTKNLEDFYDKEGFRDEEFDKGDKGTWIVDSEMVVELKDKKMESRSMVLYINRNTRTTKGNFIVRELWEDSKGYAQSKDTKYPVKMEHNRIIPTKSIADDKLRKEIENFKFFVQYGDIKDINDYKDGDISYNPNVPSYSAEYQLSNYDYNVKQLRKRYNIPTKKAPKLLIKGDGDLKGSSIGHKNLEFTFVENKEENIYFTDSINFKPTE
>NC_017349.1|WP_000581901.1|2500272_2501046_-|tandem-type-lipoprotein
MIHSKKLTPGICLVLLIILIGGYVIMTKTNGRNAQIKEAFNKTLNVYPTKNLEDFYDKEGFRDQEFDKRDKGTWIINSGMNIQLKGGALKSRAMVLYINRNTRTAKGYFLISETTEDKKGYVHNKDKKYPVKMEHNRIIPTKPITDDKLKKEIENFKFFVQYGNFKDFKDYKDGDISYNPNVPSYSANYQLNNDDYNVQQLRKRYDISTKRSPKLKLRGSGDLKGSSVGSKELEFNFIRNKEENVYYSDSINFKPTE
>NC_017349.1|WP_041201531.1|2499375_2500161_-|tandem-type-lipoprotein
MIHSKKLKLCLCLIILSIFIGGCGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKEGFRDEEFKKGDKGTWIIYSEMVIEPKGKNMETRGMVLYINRNTRTTKGNFIVNEITDDNDGRPIDNKKKYPVKMEHNKIIPTKPLPNDKLKKEIENFKFFVQYGDFKDINDYKDGDISYNPNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKQAPKLLLKGDGDLKGSSVGSRSLEFTFVENKEENIFFTDSVQFTPSEGNES
>NC_017349.1|WP_000481405.1|2516829_2518188_-|gluconate-permease
MFNEIWPLISVVLGIAILLVLIIGFKLNTFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGIMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV
>NC_017349.1|WP_000876651.1|2518304_2519858_-|gluconokinase
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTSKFADIKTYIFYHLFDRYIIDYSMASATGMFNLETLDWDVGALELLGISEEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIKENVAVYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
>NC_017349.1|WP_000990135.1|2519881_2520562_-|GntR-family-transcriptional-regulator
MMYGYPEKWLEGMTTGESIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHLKPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
>NC_017349.1|WP_000074003.1|2520715_2521480_-|MerR-family-transcriptional-regulator
MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTEQQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLNKIKNVQYYVNEASTSPITHLKDIEHVMSKSAEMKSIRHNIWISAGIIGIIQYFSIISAILMKNKWPFLIALPFMIGYGIGITIYYQRKVAYLCPNCQHIFLPSLWAVVKAKHTATTRRFECPNCQETHYCIEVPKTHMSKEQLEVPRTKNNN
>NC_017349.1|WP_000289133.1|2521644_2522337_-|GTP-pyrophosphokinase-family-protein
MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAECVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE
>NC_017349.1|WP_001117056.1|2522567_2522984_-|DUF2188-domain-containing-protein
MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEKTEVDSEYATTDNEEHIQEQSNQDKSYFDSESISNQSGGVRQREPLMDGPHPKVVESFKDV
>NC_017349.1|WP_014533133.1|2523122_2524946_-|FUSC-family-protein
MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVIICNLAFAICMMLGTLTAKTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPINLPIAPEEALYRGFAILVGGILATMMVLITILFSKNKAEVQAIQNDFKLISKLLHTYNDKSAFLKVAKTAVDSFKASDKLLITSTSSNDKLSRRFQKLLLLHTSAQGIYSELLELNAKQIRPLPDELIEMMDHIIAQLDNSDENVRYWRKEVTVTEEFQNLFNHILKIDEMVHANEARIAYEADMRKPLYSKRIYQNLTLDSIVFRNTLRYTAIMMIAIFIALMFNFEKAYWIPLSAHTILLGTSTIHAIERGMARGLGTILGVLVLSVILLFSIPTPVAVILMGIAALFTEALVGANYAIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAMGIVIAIIGLFVLGQRTASALFPNVMAEVVRKEATLFHYLFSENQYKDDVYQKNTAMNLSVKLNNMTQIYNAANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANKDRLTINEQLMGEYLATFENIAKHLELNTGLEIKILPDLPQYNYIQSAMMNIQHNGFRERDKNV
>NC_017349.1|WP_014533134.1|2525857_2527135_-|MFS-transporter
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNDFLKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAVIAVIMWFYVKPDQPLIVSDDKAIEK
>NC_017349.1|WP_000435044.1|2527681_2528293_+|DedA-family-protein
MEQIITEFISRFGYAAIFILILLENVLPIVPSEIILTFAGLMSVKSHLSILTLFIIATIASFIGLLILYYICRLISEERLYRFIDRHGKWIKLKSKDLKRANDWFKKYGVWAVFICRFIPVLRVLITIPAGVNRMNVVTFTVISLIGTTIWNFGLILLGRTLSDSFGMLMTGLHTYSRIMYVVIIIAVIYFAIRYIGKRKRVK
>NC_017349.1|WP_041201538.1|2528301_2528400_-|hypothetical-protein
MSNKLKKAVNHFNRWNDSLLFVYRNLKFMSLC

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017349_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017349_9

2744556-2744641

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017349_9

>merge|NC_017349|9|2744556-2744641|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NC_017349|9|7|2744556-2744641|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017349.1\|WP_000215635.1\|2735886_2736903_+\|HoxN/HupN/NixA-family-nickel/cobalt-transporter	unknown	unknown	gnl\|CDD\|225911
NC_017349.1\|WP_001789343.1\|2750008_2750362_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
NC_017349.1\|WP_000491379.1\|2743978_2744332_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NC_017349.1\|WP_000779131.1\|2743515_2743911_-\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|288237
NC_017349.1\|WP_000410769.1\|2738253_2738766_-\|HdeD-family-acid-resistance-protein	unknown	unknown	gnl\|CDD\|225786
NC_017349.1\|WP_000742837.1\|2744941_2745781_-\|nucleoid-occlusion-protein	unknown	unknown	gnl\|CDD\|275105
NC_017349.1\|WP_000154162.1\|2739055_2739814_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	unknown	unknown	gnl\|CDD\|224059
NC_017349.1\|WP_000672036.1\|2741775_2741967_+\|peptide-resistance-ABC-transporter-activity-modulator-VraH	unknown	unknown	unknown
NC_017349.1\|WP_001054132.1\|2742686_2743256_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_017349.1\|WP_000143659.1\|2739803_2741684_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	unknown	unknown	gnl\|CDD\|376899
NC_017349.1\|WP_001059079.1\|2742359_2742560_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_017349.1\|WP_000240855.1\|2750482_2750620_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NC_017349.1\|WP_000215579.1\|2745823_2746543_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NC_017349.1\|WP_000362510.1\|2748486_2749866_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NC_017349.1\|WP_001017417.1\|2737145_2737958_+\|arylamine-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225073
NC_017349.1\|WP_000249657.1\|2746542_2748420_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362

Protein	Function_ID	Function_description	E-value
NC_017349.1\|WP_000154162.1\|2739055_2739814_+\|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	3.13228e-111
NC_017349.1\|WP_001789343.1\|2750008_2750362_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	3.11548e-51
NC_017349.1\|WP_000215635.1\|2735886_2736903_+\|HoxN/HupN/NixA-family-nickel/cobalt-transporter	gnl\|CDD\|225911	COG3376, HoxN, High-affinity nickel permease [Inorganic ion transport and metabolism].	6.0873e-170
NC_017349.1\|WP_000779131.1\|2743515_2743911_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	4.93393e-38
NC_017349.1\|WP_000410769.1\|2738253_2738766_-\|HdeD-family-acid-resistance-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	5.06647e-22
NC_017349.1\|WP_000742837.1\|2744941_2745781_-\|nucleoid-occlusion-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.327e-113
NC_017349.1\|WP_000491379.1\|2743978_2744332_-\|DUF3147-family-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	5.87211e-38
NC_017349.1\|WP_000215579.1\|2745823_2746543_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	1.2379e-95
NC_017349.1\|WP_001054132.1\|2742686_2743256_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.48488e-16
NC_017349.1\|WP_000143659.1\|2739803_2741684_+\|peptide-resistance-ABC-transporter-permease-subunit-VraE	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.34753e-06
NC_017349.1\|WP_001059079.1\|2742359_2742560_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.4289e-30
NC_017349.1\|WP_000240855.1\|2750482_2750620_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10
NC_017349.1\|WP_000362510.1\|2748486_2749866_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_017349.1\|WP_001017417.1\|2737145_2737958_+\|arylamine-N-acetyltransferase	gnl\|CDD\|225073	COG2162, NhoA, Arylamine N-acetyltransferase [Secondary metabolites biosynthesis, transport, and catabolism].	4.65378e-106
NC_017349.1\|WP_000249657.1\|2746542_2748420_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0

>NC_017349.1|WP_000491379.1|2743978_2744332_-|DUF3147-family-protein
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLASLYIKHKGYRKGAIFTVVCWFVISLAIFSIRHL
>NC_017349.1|WP_000779131.1|2743515_2743911_-|DUF3147-family-protein
MKLTLMKFFVGGFAVLLSYIVSVALPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKSNSK
>NC_017349.1|WP_001054132.1|2742686_2743256_-|helix-turn-helix-transcriptional-regulator
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENNKSLPDIHNLLMMCELFNVTLDDLVKGTIPFVPDIKVQRSLNLWAYVMLIFMTLAAILTGPLIVYWNWAWGITVMVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTGVLSFIAFVGAIILIALISVYLANKFL
>NC_017349.1|WP_001059079.1|2742359_2742560_+|cold-shock-protein
MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEGQKVTFEITEGQRGDQAVNVQTV
>NC_017349.1|WP_000672036.1|2741775_2741967_+|peptide-resistance-ABC-transporter-activity-modulator-VraH
MKFRELVKQSYEDLKNLTVTWYNVIALAMIVIVLSVVTTPIIGIPVGLLGGAYYLKRREEKGK
>NC_017349.1|WP_000143659.1|2739803_2741684_+|peptide-resistance-ABC-transporter-permease-subunit-VraE
MTFNHIVFKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILKMLALEQMIVFLITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTIFMLVIAYILILFQSSLFLKRRSILSMMKDSIKTDVTTAKVTTAEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNDFNVVASQDAQQFESKLSQQHITFTKNYYETITVNNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNIINIHLNKDLVVKGTKNETFRVTQEDKGKVYPLNLSFNSPVVEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKKKAQAIAKQFGDKVITYDEMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>NC_017349.1|WP_000154162.1|2739055_2739814_+|peptide-resistance-ABC-transporter-ATP-binding-subunit-VraD
MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSGKTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFRKESLGFIFQDYSILPTLTVKENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHKPQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDGQIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI
>NC_017349.1|WP_000410769.1|2738253_2738766_-|HdeD-family-acid-resistance-protein
MEKGNQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLFVLINGVIQIVYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFWFIFSSIAGLFTFSGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFLFVGVIYVVDALA
>NC_017349.1|WP_001017417.1|2737145_2737958_+|arylamine-N-acetyltransferase
MNIAKLENYLQIDSSRYNRPSIEALNYYATRFMLTVPFENIDVQNGKPISINIDALFNKIVRDKRGGFCYELNTFFKTYLQQKGFNPELMSATIHIPGGGRSLNGSHASLVVSINDVFYVTDVGFGDLPLHAIPITSSEHTQPITDISGTFRAIFNSEDKDIFYVQKFENNNWHTKYEAEFKAKCIADFDKNIEYNQTHPDSIFVQHLLITMPQSFGRATMSENHLTLTKAKDGISEKLAVTKDNYKQFLTTYFGLDVTINRIENSDSKS
>NC_017349.1|WP_000215635.1|2735886_2736903_+|HoxN/HupN/NixA-family-nickel/cobalt-transporter
MTVFKNERLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGILAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGVGFYFSIGHSSVVFLMAVFLGVSVKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEVDALLESRGFVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAISFIGILSLPILFASGMSLLDTLDGVVMKYAYNWAFFNPIRKIYYNITITAISVIAALVIGMIELLQILADKLDLHGAFWAFISSIEFDYLGYILVALFLITWLISSLIWKFGRIEHKWSK
>NC_017349.1|WP_000742837.1|2744941_2745781_-|nucleoid-occlusion-protein
MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR
>NC_017349.1|WP_000215579.1|2745823_2746543_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTVEWLAEQLKEHNIELNETQKHQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>NC_017349.1|WP_000249657.1|2746542_2748420_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>NC_017349.1|WP_000362510.1|2748486_2749866_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGNTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>NC_017349.1|WP_001789343.1|2750008_2750362_-|ribonuclease-P-protein-component
MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>NC_017349.1|WP_000240855.1|2750482_2750620_-|50S-ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017349_2	2.1\|1255725\|26\|NC_017349\|CRISPRCasFinder	1255725-1255750	26	NC_017349.1	1657564-1657589	0	1.0
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	395306-395334	0	1.0
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	604945-604973	0	1.0
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	632538-632566	0	1.0
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	803606-803634	0	1.0
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	2712435-2712463	0	1.0
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	2744677-2744705	0	1.0
NC_017349_6	6.1\|2273494\|25\|NC_017349\|CRISPRCasFinder	2273494-2273518	25	NC_017349.1	2273550-2273574	0	1.0
NC_017349_8	8.1\|2513494\|18\|NC_017349\|CRT	2513494-2513511	18	NC_017349.1	2509847-2509864	0	1.0
NC_017349_8	8.6\|2513713\|18\|NC_017349\|CRT	2513713-2513730	18	NC_017349.1	2509973-2509990	0	1.0
NC_017349_8	8.6\|2513713\|18\|NC_017349\|CRT	2513713-2513730	18	NC_017349.1	2510057-2510074	0	1.0
NC_017349_8	8.6\|2513713\|18\|NC_017349\|CRT	2513713-2513730	18	NC_017349.1	2510099-2510116	0	1.0
NC_017349_8	8.6\|2513713\|18\|NC_017349\|CRT	2513713-2513730	18	NC_017349.1	2510183-2510200	0	1.0
NC_017349_9	9.1\|2744586\|26\|NC_017349\|CRISPRCasFinder	2744586-2744611	26	NC_017349.1	1657564-1657589	0	1.0
NC_017349_2	2.1\|1255725\|26\|NC_017349\|CRISPRCasFinder	1255725-1255750	26	NC_017349.1	24697-24722	1	0.962
NC_017349_2	2.1\|1255725\|26\|NC_017349\|CRISPRCasFinder	1255725-1255750	26	NC_017349.1	172791-172816	1	0.962
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	24735-24763	1	0.966
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	865636-865664	1	0.966
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NC_017349.1	1456865-1456893	1	0.966
NC_017349_8	8.1\|2513494\|18\|NC_017349\|CRT	2513494-2513511	18	NC_017349.1	1638249-1638266	1	0.944
NC_017349_8	8.4\|2513629\|18\|NC_017349\|CRT	2513629-2513646	18	NC_017349.1	2509973-2509990	1	0.944
NC_017349_8	8.4\|2513629\|18\|NC_017349\|CRT	2513629-2513646	18	NC_017349.1	2510057-2510074	1	0.944
NC_017349_8	8.4\|2513629\|18\|NC_017349\|CRT	2513629-2513646	18	NC_017349.1	2510099-2510116	1	0.944
NC_017349_8	8.4\|2513629\|18\|NC_017349\|CRT	2513629-2513646	18	NC_017349.1	2510183-2510200	1	0.944
NC_017349_9	9.1\|2744586\|26\|NC_017349\|CRISPRCasFinder	2744586-2744611	26	NC_017349.1	24697-24722	1	0.962
NC_017349_9	9.1\|2744586\|26\|NC_017349\|CRISPRCasFinder	2744586-2744611	26	NC_017349.1	172791-172816	1	0.962
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	24670-24704	2	0.943
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	73394-73428	2	0.943
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	172764-172798	2	0.943
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	172820-172854	2	0.943
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	812472-812506	2	0.943
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	848062-848096	2	0.943
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	1657582-1657616	2	0.943
NC_017349_1	1.2\|865796\|35\|NC_017349\|PILER-CR	865796-865830	35	NC_017349.1	2440501-2440535	2	0.943
NC_017349_2	2.1\|1255725\|26\|NC_017349\|CRISPRCasFinder	1255725-1255750	26	NC_017349.1	2411396-2411421	2	0.923
NC_017349_6	6.1\|2273494\|25\|NC_017349\|CRISPRCasFinder	2273494-2273518	25	NC_017349.1	1849882-1849906	2	0.92
NC_017349_9	9.1\|2744586\|26\|NC_017349\|CRISPRCasFinder	2744586-2744611	26	NC_017349.1	2411396-2411421	2	0.923

1. spacer 2.1|1255725|26|NC_017349|CRISPRCasFinder matches to position: 1657564-1657589, mismatch: 0, identity: 1.0

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
**************************

2. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 395306-395334, mismatch: 0, identity: 1.0

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttcttttcgaaa	Protospacer
*****************************

3. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 604945-604973, mismatch: 0, identity: 1.0

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttcttttcgaaa	Protospacer
*****************************

4. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 632538-632566, mismatch: 0, identity: 1.0

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttcttttcgaaa	Protospacer
*****************************

5. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 803606-803634, mismatch: 0, identity: 1.0

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttcttttcgaaa	Protospacer
*****************************

6. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 2712435-2712463, mismatch: 0, identity: 1.0

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttcttttcgaaa	Protospacer
*****************************

7. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 2744677-2744705, mismatch: 0, identity: 1.0

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttcttttcgaaa	Protospacer
*****************************

8. spacer 6.1|2273494|25|NC_017349|CRISPRCasFinder matches to position: 2273550-2273574, mismatch: 0, identity: 1.0

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttctgtgttggggccccg	Protospacer
*************************

9. spacer 8.1|2513494|18|NC_017349|CRT matches to position: 2509847-2509864, mismatch: 0, identity: 1.0

tttaccaggttcagctgg	CRISPR spacer
tttaccaggttcagctgg	Protospacer
******************

10. spacer 8.6|2513713|18|NC_017349|CRT matches to position: 2509973-2509990, mismatch: 0, identity: 1.0

tgtttccggctcacttgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
******************

11. spacer 8.6|2513713|18|NC_017349|CRT matches to position: 2510057-2510074, mismatch: 0, identity: 1.0

tgtttccggctcacttgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
******************

12. spacer 8.6|2513713|18|NC_017349|CRT matches to position: 2510099-2510116, mismatch: 0, identity: 1.0

tgtttccggctcacttgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
******************

13. spacer 8.6|2513713|18|NC_017349|CRT matches to position: 2510183-2510200, mismatch: 0, identity: 1.0

tgtttccggctcacttgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
******************

14. spacer 9.1|2744586|26|NC_017349|CRISPRCasFinder matches to position: 1657564-1657589, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

15. spacer 2.1|1255725|26|NC_017349|CRISPRCasFinder matches to position: 24697-24722, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagtagctggcgg	Protospacer
**************** *********

16. spacer 2.1|1255725|26|NC_017349|CRISPRCasFinder matches to position: 172791-172816, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctggcgg	Protospacer
*************.************

17. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 24735-24763, mismatch: 1, identity: 0.966

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttcatttcgaaa	Protospacer
******************** ********

18. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 865636-865664, mismatch: 1, identity: 0.966

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcactgcctgtagaatttcttttcgaaa	Protospacer
****.************************

19. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to position: 1456865-1456893, mismatch: 1, identity: 0.966

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
cgcattgcctgtagaatttctttccgaaa	Protospacer
***********************.*****

20. spacer 8.1|2513494|18|NC_017349|CRT matches to position: 1638249-1638266, mismatch: 1, identity: 0.944

tttaccaggttcagctgg	CRISPR spacer
tttaccacgttcagctgg	Protospacer
******* **********

21. spacer 8.4|2513629|18|NC_017349|CRT matches to position: 2509973-2509990, mismatch: 1, identity: 0.944

tgtttccggctcactcgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
***************.**

22. spacer 8.4|2513629|18|NC_017349|CRT matches to position: 2510057-2510074, mismatch: 1, identity: 0.944

tgtttccggctcactcgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
***************.**

23. spacer 8.4|2513629|18|NC_017349|CRT matches to position: 2510099-2510116, mismatch: 1, identity: 0.944

tgtttccggctcactcgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
***************.**

24. spacer 8.4|2513629|18|NC_017349|CRT matches to position: 2510183-2510200, mismatch: 1, identity: 0.944

tgtttccggctcactcgg	CRISPR spacer
tgtttccggctcacttgg	Protospacer
***************.**

25. spacer 9.1|2744586|26|NC_017349|CRISPRCasFinder matches to position: 24697-24722, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagctactatgttggggccccg	Protospacer
********* ****************

26. spacer 9.1|2744586|26|NC_017349|CRISPRCasFinder matches to position: 172791-172816, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

27. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 24670-24704, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

28. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 73394-73428, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

29. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 172764-172798, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

30. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 172820-172854, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

31. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 812472-812506, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

32. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 848062-848096, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

33. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 1657582-1657616, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

34. spacer 1.2|865796|35|NC_017349|PILER-CR matches to position: 2440501-2440535, mismatch: 2, identity: 0.943

gctggcggaaaggcagcatacaataatgtgcaagt	CRISPR spacer
gctggcggaaagtcagcttacaataatgtgcaagt	Protospacer
************ **** *****************

35. spacer 2.1|1255725|26|NC_017349|CRISPRCasFinder matches to position: 2411396-2411421, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctgacgg	Protospacer
*************.********.***

36. spacer 6.1|2273494|25|NC_017349|CRISPRCasFinder matches to position: 1849882-1849906, mismatch: 2, identity: 0.92

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttttatgttggggccccg	Protospacer
*********.*.*************

37. spacer 9.1|2744586|26|NC_017349|CRISPRCasFinder matches to position: 2411396-2411421, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgtcagcttctgtgttggggccccg	Protospacer
***.********.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017349_3	3.1\|1642927\|29\|NC_017349\|CRISPRCasFinder	1642927-1642955	29	NZ_CP009619	Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence	270872-270900	6	0.793
NC_017349_7	7.1\|2336332\|33\|NC_017349\|CRISPRCasFinder	2336332-2336364	33	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	164873-164905	8	0.758
NC_017349_7	7.1\|2336332\|33\|NC_017349\|CRISPRCasFinder	2336332-2336364	33	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	498457-498489	8	0.758

1. spacer 3.1|1642927|29|NC_017349|CRISPRCasFinder matches to NZ_CP009619 (Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence) position: , mismatch: 6, identity: 0.793

cgcattgcctgtagaatttcttttcgaaa	CRISPR spacer
tgcattacctgtagcatttcttttttcaa	Protospacer
.*****.******* *********.  **

2. spacer 7.1|2336332|33|NC_017349|CRISPRCasFinder matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 8, identity: 0.758

tcaactgtataccttttgcctttaacttaagtt	CRISPR spacer
ttatagttataccttttgcttttaatttaagtg	Protospacer
*.*    ************.*****.******

3. spacer 7.1|2336332|33|NC_017349|CRISPRCasFinder matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 8, identity: 0.758

tcaactgtataccttttgcctttaacttaagtt	CRISPR spacer
ttatagttataccttttgcttttaatttaagtg	Protospacer
*.*    ************.*****.******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

735642 : 743462

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|735642_736698_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|736697_737384_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|737358_737832_-	DoxX family protein	NA	NA	NA	NA
WP_001093557.1\|738173_738614_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637683.1\|738893_739478_-	hypothetical protein	NA	NA	NA	NA
WP_001062977.1\|739576_740290_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|740293_740713_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|740714_741383_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604519.1\|741733_742327_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	5.8e-38	42.9
WP_001217792.1\|742310_743462_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	1.2e-23	36.1

DBSCAN-SWA_2

755434 : 769829

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663033.1\|755434_756493_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	3.9e-21	26.4
WP_000197263.1\|756843_757392_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429005.1\|757993_758911_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.4
WP_000193751.1\|759193_760699_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|761039_761540_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|761559_762426_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|763226_763625_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|763587_765693_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|765810_766782_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_014532584.1\|766962_767082_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|767156_768128_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245569.1\|768114_769071_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	7.2e-06	60.0
WP_000616870.1\|769067_769829_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	5.0e-18	31.6

DBSCAN-SWA_3

849351 : 917187

Staphylococcus_phage(76.54%)

plate,holin,tail,terminase,head,capsid,portal,coat,integrase

attL 856587:856602|attR 898542:898557

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571213.1\|849351_850377_+	methionine ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.0e-26	33.3
WP_000520233.1\|850369_851065_+	ABC transporter permease	NA	NA	NA	NA
WP_000732330.1\|851082_851904_+	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000264629.1\|852046_853267_-\|integrase	site-specific integrase	Q4ZE80	Staphylococcus_phage	3.0e-97	46.8
WP_000668211.1\|853281_853983_-	helix-turn-helix transcriptional regulator	Q4ZE79	Staphylococcus_phage	1.4e-11	35.3
WP_001245563.1\|854126_854339_+	helix-turn-helix transcriptional regulator	Q4ZE78	Staphylococcus_phage	1.1e-15	58.6
WP_001138307.1\|854339_854612_+	hypothetical protein	Q4ZE77	Staphylococcus_phage	1.9e-36	81.1
WP_000784877.1\|854623_854770_+	hypothetical protein	NA	NA	NA	NA
WP_001058499.1\|854762_854975_+	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	4.4e-17	67.6
WP_001038253.1\|854976_855336_+	hypothetical protein	NA	NA	NA	NA
WP_001103937.1\|855336_855636_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	4.4e-18	54.4
WP_000344759.1\|855710_857324_+	hypothetical protein	A0A1W6JPF4	Staphylococcus_phage	1.1e-245	77.0
856587:856602	attL	NA	NA	NA	NA
WP_000148366.1\|857494_858298_+	bifunctional DNA primase/polymerase	Q4ZE69	Staphylococcus_phage	1.0e-146	94.4
WP_001149386.1\|858284_858557_+	hypothetical protein	Q4ZE68	Staphylococcus_phage	5.3e-39	87.8
WP_001019275.1\|858558_859200_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	3.2e-111	93.0
WP_001190614.1\|859548_859890_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	2.9e-58	100.0
WP_000449694.1\|859903_860137_+	hypothetical protein	NA	NA	NA	NA
WP_001193445.1\|860147_860669_+	hypothetical protein	NA	NA	NA	NA
WP_000771351.1\|860758_861286_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	5.1e-86	94.3
WP_078064649.1\|861417_861630_+	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	8.6e-29	88.6
WP_001293082.1\|861626_862196_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	3.9e-100	97.4
WP_000935289.1\|862270_862630_-	hypothetical protein	NA	NA	NA	NA
WP_000362904.1\|862746_863136_-	hypothetical protein	NA	NA	NA	NA
WP_000369273.1\|863137_864349_-	hypothetical protein	NA	NA	NA	NA
WP_173361317.1\|864375_864768_+	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000752917.1\|866138_866333_+	CsbD family protein	NA	NA	NA	NA
WP_001183851.1\|866566_867418_-	DUF368 domain-containing protein	NA	NA	NA	NA
WP_000168845.1\|867746_868508_+	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3
WP_000205569.1\|868605_869913_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_001006453.1\|870018_871269_+	cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-110	44.8
WP_001010508.1\|871258_871723_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_001074405.1\|871873_873271_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_001145730.1\|873338_874388_-\|integrase	site-specific integrase	A0A0H4ISP4	Staphylococcus_phage	2.7e-203	100.0
WP_000143212.1\|874499_874700_+	excisionase	Q38044	Staphylococcus_phage	5.6e-30	100.0
WP_000391592.1\|874636_875542_-	hypothetical protein	A0A0F6N3N6	Staphylococcus_phage	1.4e-168	100.0
WP_000874709.1\|875573_876212_-	LexA family transcriptional regulator	A0A0E3TAG1	Staphylococcus_phage	1.3e-115	99.5
WP_001106625.1\|876403_876658_+	helix-turn-helix transcriptional regulator	B7T095	Staphylococcus_virus	1.8e-41	100.0
WP_000398749.1\|876673_876841_+	hypothetical protein	Q4ZA65	Staphylococcus_virus	9.8e-20	98.2
WP_000394410.1\|876891_877374_-	hypothetical protein	A0A0N9BAX2	Staphylococcus_phage	1.1e-82	100.0
WP_000933365.1\|877819_878005_+	helix-turn-helix transcriptional regulator	A0A0H4IP57	Staphylococcus_phage	1.3e-25	100.0
WP_001148639.1\|878006_878756_+	phage antirepressor KilAC domain-containing protein	A0A1W6JPN2	Staphylococcus_phage	4.4e-136	99.6
WP_001555746.1\|878771_878987_+	hypothetical protein	E9LT76	Staphylococcus_phage	5.0e-32	98.6
WP_000122246.1\|878942_879188_-	hypothetical protein	E9LT77	Staphylococcus_phage	6.9e-38	100.0
WP_000594787.1\|879258_879489_+	hypothetical protein	A0A0H4ISQ0	Staphylococcus_phage	5.9e-31	97.3
WP_001285948.1\|879472_879634_+	DUF1270 domain-containing protein	A9CR58	Staphylococcus_phage	1.1e-20	98.1
WP_000291103.1\|879735_879996_+	DUF1108 family protein	A1KX65	Staphylococcus_virus	4.4e-43	98.8
WP_000002521.1\|880009_880489_+	siphovirus Gp157 family protein	Q4ZCX2	Staphylococcus_virus	2.6e-81	97.5
WP_001043066.1\|880488_881127_+	ERF family protein	M9NSS5	Staphylococcus_phage	2.8e-115	99.5
WP_000934780.1\|881126_881552_+	single-stranded DNA-binding protein	R4IG44	Staphylococcus_phage	3.0e-73	100.0
WP_001121816.1\|881565_882240_+	hypothetical protein	D2JGK3	Staphylococcus_phage	1.2e-121	94.2
WP_001037659.1\|882232_882985_+	DnaD domain protein	B7T0A7	Staphylococcus_virus	1.9e-118	87.3
WP_001132244.1\|882984_883341_+	hypothetical protein	B7T0A8	Staphylococcus_virus	6.9e-63	99.2
WP_001106158.1\|883337_884579_+	AAA family ATPase	C8CGZ3	Staphylococcus_phage	6.3e-228	99.0
WP_001024400.1\|884575_884791_+	hypothetical protein	A9CR72	Staphylococcus_phage	1.8e-34	97.2
WP_001123688.1\|884793_885015_+	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_000049792.1\|885024_885429_+	DUF1064 domain-containing protein	Q6R835	Staphylococcus_virus	4.6e-71	98.5
WP_001187254.1\|885433_885619_+	DUF3113 family protein	Q4ZA46	Staphylococcus_virus	4.1e-27	100.0
WP_000907417.1\|885619_886237_+	hypothetical protein	A0A0H3U4U9	Staphylococcus_phage	1.0e-82	99.0
WP_001124144.1\|886237_886486_+	hypothetical protein	A0A2I6PDI0	Staphylococcus_phage	4.0e-41	95.1
WP_000693985.1\|886499_886880_+	hypothetical protein	Q4ZDG8	Staphylococcus_virus	4.0e-32	56.8
WP_001105605.1\|887067_887352_+	hypothetical protein	Q9G014	Staphylococcus_virus	4.9e-43	92.6
WP_001065120.1\|887344_887593_+	DUF1024 family protein	B7T0H8	Staphylococcus_virus	1.3e-36	97.6
WP_000181820.1\|887585_888098_+	dUTP pyrophosphatase	Q4ZDG4	Staphylococcus_virus	3.4e-87	97.1
WP_000195825.1\|888134_888341_+	DUF1381 domain-containing protein	A0A059T622	Staphylococcus_phage	4.9e-21	98.5
WP_000595249.1\|888337_888511_+	transcriptional activator RinB	Q4ZBK0	Staphylococcus_phage	1.9e-21	98.2
WP_000989998.1\|888511_888658_+	hypothetical protein	A0A059T5A8	Staphylococcus_phage	2.2e-15	100.0
WP_000162701.1\|888681_889104_+	RinA family phage transcriptional activator	A0A0F6N3E5	Staphylococcus_phage	1.2e-74	100.0
WP_000594081.1\|889435_889930_+\|terminase	terminase	A0A059T7P8	Staphylococcus_phage	1.7e-75	99.4
WP_001037580.1\|889922_891146_+\|terminase	PBSX family phage terminase large subunit	A0A059T7K2	Staphylococcus_phage	8.3e-241	99.5
WP_078064613.1\|891142_892567_+\|portal	phage portal protein	A0A0E3T9I6	Staphylococcus_phage	3.8e-269	98.7
WP_000609643.1\|892535_893486_+\|head	phage head morphogenesis protein	A0A0H3U2Z4	Staphylococcus_phage	9.8e-173	98.1
WP_001019218.1\|893581_894166_+	DUF4355 domain-containing protein	M9NRJ1	Staphylococcus_phage	2.9e-74	99.0
WP_000235170.1\|894182_895097_+\|capsid	phage major capsid protein	A0A059T7K3	Staphylococcus_phage	1.3e-169	99.3
WP_000002930.1\|895108_895252_+	hypothetical protein	A0A059T673	Staphylococcus_phage	7.9e-18	100.0
WP_000177353.1\|895257_895608_+\|head,tail	phage head-tail adapter protein	A0A0H3U2R5	Staphylococcus_phage	3.2e-60	99.1
WP_000483039.1\|895619_895955_+\|head	phage head closure protein	Q4ZBR2	Staphylococcus_phage	2.8e-58	97.3
WP_001151322.1\|895941_896355_+	HK97 gp10 family phage protein	A0A0N9BAY5	Staphylococcus_phage	1.2e-74	98.5
WP_000270192.1\|896367_896793_+	DUF3168 domain-containing protein	Q4ZBQ9	Staphylococcus_phage	5.5e-75	100.0
WP_000057585.1\|896793_897351_+	hypothetical protein	A0A059T675	Staphylococcus_phage	4.1e-102	100.0
WP_000134338.1\|897417_897930_+	hypothetical protein	A0A059T5B1	Staphylococcus_phage	2.1e-92	99.4
WP_041201307.1\|897974_898259_+	hypothetical protein	A0A059T626	Staphylococcus_phage	2.3e-45	98.9
WP_000379437.1\|898262_901148_+\|terminase	terminase	M9NRJ5	Staphylococcus_phage	0.0e+00	98.9
898542:898557	attR	NA	NA	NA	NA
WP_000560190.1\|901162_902104_+\|tail	phage tail family protein	A0A059T7K5	Staphylococcus_phage	1.4e-179	99.0
WP_001122008.1\|902114_904001_+\|tail	phage tail protein	A0A059T677	Staphylococcus_phage	0.0e+00	98.9
WP_000323243.1\|904013_905912_+	hypothetical protein	Q4ZA90	Staphylococcus_virus	0.0e+00	97.9
WP_000259641.1\|905911_907735_+\|plate	phage baseplate upper protein	A0A059T627	Staphylococcus_phage	1.9e-310	97.5
WP_000705904.1\|907734_908121_+	DUF2977 domain-containing protein	M9NRJ7	Staphylococcus_phage	3.7e-46	79.0
WP_000916018.1\|908113_908290_+	XkdX family protein	M9QX31	Staphylococcus_phage	8.8e-19	88.0
WP_000467321.1\|908329_908635_+	DUF2951 family protein	A0A059T679	Staphylococcus_phage	1.7e-41	97.0
WP_000524027.1\|908771_910646_+	glucosaminidase domain-containing protein	Q4ZA83	Staphylococcus_virus	0.0e+00	92.0
WP_000276617.1\|910658_913253_+\|plate	BppU family phage baseplate upper protein	Q4ZC48	Staphylococcus_virus	7.9e-273	57.1
WP_000354116.1\|913308_913746_+\|holin	phage holin	B7T0F0	Staphylococcus_virus	5.9e-72	97.2
WP_001148144.1\|913726_915172_+	SH3 domain-containing protein	A0A059T7Q7	Staphylococcus_phage	2.2e-293	99.2
WP_000201920.1\|916070_916250_+	hypothetical protein	M9QYR8	Staphylococcus_phage	4.1e-24	100.0
WP_000455173.1\|916271_916799_+	DUF4065 domain-containing protein	M9QX37	Staphylococcus_phage	3.4e-98	100.0
WP_043854724.1\|916770_917187_+	hypothetical protein	M9QRV7	Staphylococcus_phage	5.4e-75	99.3

DBSCAN-SWA_4

1614435 : 1622747

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213904.1\|1614435_1615221_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.8e-18	27.9
WP_000924217.1\|1615346_1616237_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.4e-27	33.5
WP_001062177.1\|1616246_1617593_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683923.1\|1617706_1618807_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	2.3e-08	30.6
WP_000624575.1\|1618809_1619487_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1619617_1620724_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217265.1\|1620947_1622747_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.2e-55	36.3

DBSCAN-SWA_5

1692409 : 1701452

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1692409_1692928_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594977.1\|1692949_1695223_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
WP_000749803.1\|1695425_1697705_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1697979_1698240_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1698258_1699398_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019179.1\|1699420_1700446_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1700447_1701452_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_6

1816472 : 1900248

Staphylococcus_phage(92.59%)

tRNA,protease,integrase

attL 1898377:1898391|attR 1900253:1900267

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001266157.1\|1816472_1817117_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_000434769.1\|1817131_1817923_-	phosphotransferase family protein	NA	NA	NA	NA
WP_000411093.1\|1818472_1819321_-	D-amino-acid transaminase	NA	NA	NA	NA
WP_000265417.1\|1819324_1820734_-	Mn(2+)-dependent dipeptidase Sapep	NA	NA	NA	NA
WP_001051855.1\|1821222_1821645_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_001261783.1\|1821661_1822357_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000004344.1\|1822353_1824015_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_000284996.1\|1824421_1825690_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	4.1e-57	100.0
WP_001050579.1\|1825806_1832364_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	6.3e-303	95.4
WP_000836462.1\|1832690_1833002_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	8.2e-52	98.1
WP_014533117.1\|1833023_1835441_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.3
WP_001025061.1\|1835729_1836911_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526539.1\|1837020_1837974_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1837970_1838534_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1838653_1839055_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1839626_1840454_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|1840456_1840576_-	hypothetical protein	NA	NA	NA	NA
WP_001196352.1\|1840687_1841689_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	5.9e-184	99.4
WP_001008551.1\|1841810_1842275_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159029.1\|1842287_1843469_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.5e-226	99.5
WP_000493886.1\|1843479_1844112_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.4e-112	99.0
WP_000077346.1\|1844118_1845162_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	3.1e-196	99.1
WP_001261682.1\|1845642_1847145_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.1e-29	98.6
WP_000221183.1\|1847666_1847981_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	3.1e-51	95.2
WP_000989110.1\|1847980_1849273_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.5e-224	97.9
WP_000163241.1\|1849290_1849686_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.9e-72	98.5
WP_001032833.1\|1850035_1850890_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1851165_1851390_-	hypothetical protein	NA	NA	NA	NA
WP_000671048.1\|1851588_1852059_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	4.8e-80	96.8
WP_001153739.1\|1852171_1852615_+	competence protein ComK	NA	NA	NA	NA
WP_001030461.1\|1852601_1853045_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.9e-54	84.4
WP_041201592.1\|1853342_1853978_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1854403_1855117_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1855374_1855677_+	hypothetical protein	NA	NA	NA	NA
WP_001200549.1\|1855931_1856297_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	1.4e-58	97.5
WP_000623471.1\|1856293_1856647_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	99.1
WP_000453295.1\|1856896_1857730_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.0e-158	99.3
WP_000366163.1\|1857941_1858850_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933822.1\|1858974_1860168_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109905.1\|1860538_1862131_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_078056470.1\|1862426_1863173_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.6e-141	98.0
WP_000672019.1\|1863177_1863651_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_000718107.1\|1863716_1863974_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778511.1\|1863970_1864972_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	3.1e-185	97.3
WP_000348354.1\|1864976_1866455_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	4.8e-283	97.6
WP_072491906.1\|1866613_1867069_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	7.5e-78	96.6
WP_078064628.1\|1867371_1868022_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	8.5e-51	85.6
WP_000070663.1\|1868102_1869098_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.1e-76	97.2
WP_000658995.1\|1869154_1869922_-	hypothetical protein	NA	NA	NA	NA
WP_000745800.1\|1870084_1870528_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000222274.1\|1871057_1873472_+	polysaccharide lyase 8 family protein	NA	NA	NA	NA
WP_001044433.1\|1873531_1874386_-	M23 family metallopeptidase	E5G070	Clostridium_phage	6.4e-06	37.9
WP_000028660.1\|1875841_1877398_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.2e-287	99.2
WP_001038711.1\|1878630_1879347_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	7.8e-130	97.9
WP_111763542.1\|1879451_1879559_+	hypothetical protein	NA	NA	NA	NA
WP_001038740.1\|1879507_1880227_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	2.8e-127	97.1
WP_001038863.1\|1880352_1881072_-\|protease	serine protease	A0A2H4PQP7	Staphylococcus_phage	1.7e-121	92.1
WP_001039442.1\|1881129_1881852_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	1.2e-127	95.8
WP_001039425.1\|1881976_1882684_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.2e-124	96.2
WP_001092770.1\|1883638_1884220_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	1.7e-50	62.2
WP_000586137.1\|1884693_1885392_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	7.1e-112	93.1
WP_000581545.1\|1885388_1886150_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	6.5e-127	95.3
WP_001096793.1\|1886146_1886839_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	1.4e-120	97.4
WP_000849076.1\|1886861_1888235_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	9.7e-246	94.5
WP_000517786.1\|1888244_1888763_-	flavoprotein	A0A2H4PQG9	Staphylococcus_phage	1.9e-93	97.7
WP_000130810.1\|1888778_1890023_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.0e-209	87.7
WP_001092609.1\|1890015_1893009_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	92.3
WP_000432510.1\|1893073_1893217_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	3.8e-20	100.0
WP_000416757.1\|1893952_1894096_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	9.9e-13	76.6
WP_000782475.1\|1894338_1895322_-	leukocidin/hemolysin toxin family protein	A0A2H4PQH7	Staphylococcus_phage	2.6e-184	98.2
WP_000473595.1\|1895323_1896259_-	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	1.5e-173	99.3
WP_014532652.1\|1897199_1897436_+	hypothetical protein	NA	NA	NA	NA
WP_000848320.1\|1897456_1898233_+	DUF1828 domain-containing protein	NA	NA	NA	NA
1898377:1898391	attL	NA	NA	NA	NA
WP_000197444.1\|1898628_1899123_+	hypothetical protein	NA	NA	NA	NA
WP_000146087.1\|1899198_1900248_+\|integrase	site-specific integrase	A0A2H4JB53	uncultured_Caudovirales_phage	1.3e-181	89.4
1900253:1900267	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NC_017349.1|WP_000416757.1|1893952_1894096_-|gallidermin/nisin-family-lantibiotic

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_017349.1|WP_000416757.1|1893952_1894096_-|gallidermin/nisin-family-lantibiotic

1893952_1894096_-

47 aa aa

1816472-1900248

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_017349_6	Orphan	6.1\|2273494\|25\|NC_017349\|CRISPRCasFinder	2273494-2273518	25	1849882-1849906	2

1. spacer 6.1|2273494|25|NC_017349|CRISPRCasFinder matches to NC_017349 position: 1849882-1849906, mismatch: 2

tgtcagcttctgtgttggggccccg	CRISPR spacer
tgtcagcttttatgttggggccccg	Protospacer
*********.*.*************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017349

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information