CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016783	Corynebacterium diphtheriae INCA 402, complete sequence	1 crisprs	cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,csa3,cas3,WYL,cas4,DinG	0	5	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_016783_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016783_1

39263-40319

TypeI-E

I-E

Consensus_repeat	Method
GTTTTCCCCGCACTAGCAGGGATGAGCC	PILER-CR
GTTTTCCCCGCACTAGCAGGGATGAGCC	CRISPRCasFinder
GTTTTCCCCGCACTAGCAGGGATGAGCC	CRT

17 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

The CRISPR arrays of NC_016783_1

>merge|NC_016783|1|39263-40319|PILER-CR,CRISPRCasFinder,CRT
GTTTTCCCCGCACTAGCAGGGATGAGCCGGTACGGCTGTCCCATGTGCGGTTGCTTTTGGCGTTTTCCCCGCACTAGCAGGGATGAGCCTGGGTTGGGGTGCACAACAACGAGGGAGAATCAGTTTTCCCCGCACTAGCAGGGATGAGCCCAAATTTCCACGCCTCTGGCCCCTCACCTGGGCGTTTTCCCCGCACTAGCAGGGATGAGCCCTAACCCAAAAACCATCCTCTTCGCCCAACACGTTTTCCCCGCACTAGCAGGGATGAGCCCTGCTGCACTTCGGATTTGCTGGCCATATCAGCGTTTTCCCCGCACTAGCAGGGATGAGCCCTGACCAAGCCCGATGCGCTCACCGATCCAGACGTTTTCCCCGCACTAGCAGGGATGAGCCCGCAAACAGGCCCGTGAAGCCGCCCGCGCTGTCGTTTTCCCCGCACTAGCAGGGATGAGCCCTAGTTGCTGAAGCACGAGCGGAAAATAAAACAGTTTTCCCCGCACTAGCAGGGATGAGCCCGCTGTCCCGAAGATAGAGGTGGTTTCGCAAATGTTTTCCCCGCACTAGCAGGGATGAGCCGCAAAAACACAGTGCTTAGCTTTCGTCACGTACGTTTTCCCCGCACTAGCAGGGATGAGCCGGATGGTGTAATCAATGCCCGCATAGGTCCCGTGTTTTCCCCGCACTAGCAGGGATGAGCCCGCCCACAGGACCAGCAGTGAGGTCGACCCGTAGTTTTCCCCGCACTAGCAGGGATGAGCCCATTGAGTGGGAAGAAGCCCCAGCAAACTTTGAGTTTTCCCCGCACTAGCAGGGATGAGCCCCTTGCCCGCGCCGCGGCGCGGGTTGCTCAAAAGTTTTCCCCGCACTAGCGGGGATGAGCCGTTGTTAACGGATCCACGAGACACACCCAGTATGTTTTCCCCGCACTAGCGGGGATGAGCCGTCATAATCAGCACTGTCAATCCTCATGTATTGGTTTTCCCCGCGTCAGCGGGGATGAGCCCAGGGACTTTGAGAACTGGACCGCCGTGATTCCCTGCACTAGCAGGGTGGATGA

>NC_016783|1|1|39263-40143|PILER-CR
GTTTTCCCCGCACTAGCAGGGATGAGCC	GGTACGGCTGTCCCATGTGCGGTTGCTTTTGGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	TGGGTTGGGGTGCACAACAACGAGGGAGAATCA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CAAATTTCCACGCCTCTGGCCCCTCACCTGGGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTAACCCAAAAACCATCCTCTTCGCCCAACAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTGCTGCACTTCGGATTTGCTGGCCATATCAGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTGACCAAGCCCGATGCGCTCACCGATCCAGAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCAAACAGGCCCGTGAAGCCGCCCGCGCTGTC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTAGTTGCTGAAGCACGAGCGGAAAATAAAACA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCTGTCCCGAAGATAGAGGTGGTTTCGCAAAT
GTTTTCCCCGCACTAGCAGGGATGAGCC	GCAAAAACACAGTGCTTAGCTTTCGTCACGTAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	GGATGGTGTAATCAATGCCCGCATAGGTCCCGT
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCCCACAGGACCAGCAGTGAGGTCGACCCGTA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CATTGAGTGGGAAGAAGCCCCAGCAAACTTTGA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CCTTGCCCGCGCCGCGGCGCGGGTTGCTCAAAA
GTTTTCCCCGCACTAGCGGGGATGAGCC

>NC_016783|1|1|39263-40319|CRISPRCasFinder
GTTTTCCCCGCACTAGCAGGGATGAGCC	GGTACGGCTGTCCCATGTGCGGTTGCTTTTGGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	TGGGTTGGGGTGCACAACAACGAGGGAGAATCA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CAAATTTCCACGCCTCTGGCCCCTCACCTGGGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTAACCCAAAAACCATCCTCTTCGCCCAACAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTGCTGCACTTCGGATTTGCTGGCCATATCAGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTGACCAAGCCCGATGCGCTCACCGATCCAGAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCAAACAGGCCCGTGAAGCCGCCCGCGCTGTC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTAGTTGCTGAAGCACGAGCGGAAAATAAAACA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCTGTCCCGAAGATAGAGGTGGTTTCGCAAAT
GTTTTCCCCGCACTAGCAGGGATGAGCC	GCAAAAACACAGTGCTTAGCTTTCGTCACGTAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	GGATGGTGTAATCAATGCCCGCATAGGTCCCGT
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCCCACAGGACCAGCAGTGAGGTCGACCCGTA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CATTGAGTGGGAAGAAGCCCCAGCAAACTTTGA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CCTTGCCCGCGCCGCGGCGCGGGTTGCTCAAAA
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTTGTTAACGGATCCACGAGACACACCCAGTAT
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTCATAATCAGCACTGTCAATCCTCATGTATTG
GTTTTCCCCGCGTCAGCGGGGATGAGCC	CAGGGACTTTGAGAACTGGACCGCCG
TGATTCCCTGCACTAGCAGGGTGGATGA

>NC_016783|1|1|39263-40265|CRT
GTTTTCCCCGCACTAGCAGGGATGAGCC	GGTACGGCTGTCCCATGTGCGGTTGCTTTTGGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	TGGGTTGGGGTGCACAACAACGAGGGAGAATCA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CAAATTTCCACGCCTCTGGCCCCTCACCTGGGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTAACCCAAAAACCATCCTCTTCGCCCAACAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTGCTGCACTTCGGATTTGCTGGCCATATCAGC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTGACCAAGCCCGATGCGCTCACCGATCCAGAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCAAACAGGCCCGTGAAGCCGCCCGCGCTGTC
GTTTTCCCCGCACTAGCAGGGATGAGCC	CTAGTTGCTGAAGCACGAGCGGAAAATAAAACA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCTGTCCCGAAGATAGAGGTGGTTTCGCAAAT
GTTTTCCCCGCACTAGCAGGGATGAGCC	GCAAAAACACAGTGCTTAGCTTTCGTCACGTAC
GTTTTCCCCGCACTAGCAGGGATGAGCC	GGATGGTGTAATCAATGCCCGCATAGGTCCCGT
GTTTTCCCCGCACTAGCAGGGATGAGCC	CGCCCACAGGACCAGCAGTGAGGTCGACCCGTA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CATTGAGTGGGAAGAAGCCCCAGCAAACTTTGA
GTTTTCCCCGCACTAGCAGGGATGAGCC	CCTTGCCCGCGCCGCGGCGCGGGTTGCTCAAAA
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTTGTTAACGGATCCACGAGACACACCCAGTAT
GTTTTCCCCGCACTAGCGGGGATGAGCC	GTCATAATCAGCACTGTCAATCCTCATGTATTG
GTTTTCCCCGCGTCAGCGGGGATGAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016783.1\|WP_014302666.1\|44654_45320_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NC_016783.1\|WP_014302668.1\|46265_46613_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NC_016783.1\|WP_014302667.1\|45323_46259_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_016783.1\|WP_014302664.1\|42810_43944_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NC_016783.1\|WP_014302654.1\|28839_30639_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_016783.1\|WP_014302665.1\|43948_44653_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|378243
NC_016783.1\|WP_014302670.1\|49026_50535_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016783.1\|WP_014302661.1\|36224_39026_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NC_016783.1\|WP_014302656.1\|31287_32376_+\|glycine-oxidase-ThiO	unknown	unknown	gnl\|CDD\|274092
NC_016783.1\|WP_014302657.1\|32359_32560_+\|sulfur-carrier-protein-ThiS	unknown	unknown	gnl\|CDD\|273754
NC_016783.1\|WP_158307791.1\|35331_35481_+\|hypothetical-protein	unknown	unknown	unknown
NC_016783.1\|WP_014302669.1\|47008_49030_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016783.1\|WP_014302658.1\|32561_33347_+\|thiazole-synthase	unknown	unknown	gnl\|CDD\|234687
NC_016783.1\|WP_014302662.1\|40492_42166_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NC_016783.1\|WP_014302655.1\|30622_31291_+\|thiamine-phosphate-synthase	unknown	unknown	gnl\|CDD\|234590
NC_016783.1\|WP_014302660.1\|34353_35169_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|237797
NC_016783.1\|WP_014307720.1\|27147_27765_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NC_016783.1\|WP_003849883.1\|46620_46890_-\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907
NC_016783.1\|WP_014302663.1\|42169_42796_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NC_016783.1\|WP_014302659.1\|33346_34357_+\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|235528

Protein	Function_ID	Function_description	E-value
NC_016783.1\|WP_014302666.1\|44654_45320_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.54139e-78
NC_016783.1\|WP_014302668.1\|46265_46613_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	3.33539e-41
NC_016783.1\|WP_014302667.1\|45323_46259_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.78081e-125
NC_016783.1\|WP_014302664.1\|42810_43944_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.92863e-158
NC_016783.1\|WP_014302654.1\|28839_30639_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_016783.1\|WP_014302665.1\|43948_44653_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	8.43322e-41
NC_016783.1\|WP_014302670.1\|49026_50535_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.00936e-107
NC_016783.1\|WP_014307720.1\|27147_27765_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	2.72806e-26
NC_016783.1\|WP_014302656.1\|31287_32376_+\|glycine-oxidase-ThiO	gnl\|CDD\|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	5.08136e-128
NC_016783.1\|WP_014302657.1\|32359_32560_+\|sulfur-carrier-protein-ThiS	gnl\|CDD\|273754	TIGR01683, thiamine_biosynthesis_protein_ThiS, thiamine biosynthesis protein ThiS. This model represents ThiS, a small, ubiquitin-like thiamine biosynthesis protein related to MoaD, a molybdenum cofactor biosynthesis protein. Both proteins are involved in sulfur transfer. ThiS has a conserved Gly-Gly C-terminus that is modified, in reactions requiring ThiI, ThiF, IscS, and a sulfur atom from Cys, into the thiocarboxylate that provides the sulfur for thiazole biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	8.21875e-20
NC_016783.1\|WP_014302669.1\|47008_49030_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.46217e-121
NC_016783.1\|WP_014302659.1\|33346_34357_+\|ThiF-family-adenylyltransferase	gnl\|CDD\|235528	PRK05600, PRK05600, thiamine biosynthesis protein ThiF; Validated.	0
NC_016783.1\|WP_014302662.1\|40492_42166_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	3.39008e-106
NC_016783.1\|WP_014302655.1\|30622_31291_+\|thiamine-phosphate-synthase	gnl\|CDD\|234590	PRK00043, thiE, thiamine phosphate synthase.	4.93107e-63
NC_016783.1\|WP_014302660.1\|34353_35169_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|237797	PRK14713, PRK14713, bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.	2.07941e-109
NC_016783.1\|WP_014302661.1\|36224_39026_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	9.62771e-92
NC_016783.1\|WP_003849883.1\|46620_46890_-\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	2.52021e-46
NC_016783.1\|WP_014302663.1\|42169_42796_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	7.23002e-33
NC_016783.1\|WP_014302658.1\|32561_33347_+\|thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	1.32018e-147

>NC_016783.1|WP_014302661.1|36224_39026_+|CRISPR-associated-helicase/endonuclease-Cas3
MSVVDQADQWRRARSVQAYSLWAKSGSEDLYLRLPQHLIDAACVAEWLWNNWVSDSLKSTLSAAWRLPAEEVGRLYTFYAGTHDVGKATISFQRLVEKTSHGNYLLGPVREAGLSLQWTLNEGEGKKFPHGMASALIIAAWLEKHDIDPSSAARLSFIADAHHGFASDEELYRSHEDTLDYYPPEWLVVHAEILDSMAEITDIGETLEELADQSTPSAPAMQIMTGLVIMADWIASDEKAFPYVCDSSQHDRVVEGMSHVNLPPAWVPTDVPDNVETLFRDTFTWPDSYQVRPVQRAAVTVARAVQDPTLIIIEAPTGEGKTEAGLATSHILGQKTGAQGIFFAAPTMSTANGLFERTKNWAQCTSSRGEVASLYLAHSKNKLSRPFQSLRFTSIGEDDHLEKHGSVVASQWLSGRYRGILSDFVVGTVDQVLMMALQVRFSMLRHVGLAGKIVIIDEVHAYDAYMSQYLYLTLQWLAKYGVSVILMSATLPPQQRARLVNAYASQVCKKADASALNSDAYPLITAVNKKGISVTEVPQENSDTTIKIRRIDDSLPALGGMFSDLLVDGGIALVICNTIRRAQQAYDFLKEIFPDEVELHHAAFIATQRSEKEDALRESLGPYASRGEDRPWRRIVVATQVAEQSLDIDADVLVTDIAPIDLIIQRAGRLHRHERPHSDRPEILGQPQIFIRGINNEEISGEVPEFDSGAAAIYGEKILYATVAYLPDEFHRPSDIPKLVKNVYSDTPCIPENWKEQWEQACVKAKENYEKSVRKAQTFSFPQPHMARTLRDLFKQQHSNSVDKNEESGSAQVRDAEFSIEVVALLKTEYGYHPFGRKEEIENGRELTWKETEALAGNTVRLPTRMTRRDSDFNAVIDSLEAQTPPEWQRSGLIKGQVALLFDERGEARVGRFLVRYTNERGLEVEVCPKEDA
>NC_016783.1|WP_158307791.1|35331_35481_+|hypothetical-protein
MIVTVIEAEPVEPIEPHMRAAWKAMSKRRKDTLAYIRHTINALYNRKSH
>NC_016783.1|WP_014302660.1|34353_35169_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MTPHILTIAGSDPSGGAGIQADLKSIMAAGGYGMAAITALTAQNTCGVTAIHTPPTEFLSEQLRAISDDITIHAIKIGMIGSSDAATATATWLDQLPHTPIVVLDPVMVATSGSVLGQRHYFEPLLHHATVITPNLPELAVLTNNHDPEQAEHAARSLAEQYDCAVLLKGGHRHGTDDLGNTWITASGPQFHAPSPRIHTTNTHGTGCSLSSALATRLVIEPPEPALHWATTWLNGAIAHGSDLNVGHGNGPVDHSYRLGEYSANCNTIES
>NC_016783.1|WP_014302659.1|33346_34357_+|ThiF-family-adenylyltransferase
MLDELERQRVARQLRLPGFGIEQQERLNKGRVLVIGAGGLGSPALQSLVAAGVGSIRLVDNDTVDVSNIQRQILFGVGDVGRSKVHVAAERLRAIQPGIRIDAHTERLTAHNAHELAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHMGVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGSITTYNALTSTFRTYTVGRDPLRPAARTLHTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWDDTTAIQHALDNITTDNVVVVCASGIRSAAFIEQFAHLNPHLTFHNVPSGINELP
>NC_016783.1|WP_014302658.1|32561_33347_+|thiazole-synthase
MLTIADRSFQSHLIMGTGGASSFDTLEKSLIASGTELTTVAMRRHAAHTGAHGESVFELMQRLNITPLPNTAGCRTARDAILTAQLAREALDTSWIKVEVIADDTTLLPDVLELIDATETLTNDGFTVLAYTSDDPVVAQRLEDAGAAAVMPLGSPIGTGLGILNPHNIELICSRATVPVLLDAGIGTASDATLAMELGCAGVLLASAINRCINPITMATAMKHAVEAGRLAREAGRIPRREHAVASSSFEGLASWADEVL
>NC_016783.1|WP_014302657.1|32359_32560_+|sulfur-carrier-protein-ThiS
MDIYINDTLTTIESPQLTEIISNHCNGIRPGIAVAINQRVIPRSQWDTTTVTAGDHLDILTAVQGG
>NC_016783.1|WP_014302656.1|31287_32376_+|glycine-oxidase-ThiO
MKIAVVGGGIVGLSTAFELSTRGYNVHVFDPNPASGASHFAGGMLAPAAEVQFQQDPLFPLMKRAGKLWPDMVRWVAQHTNLPTGYRTEGTLVVAADRADAEHLKQLRATQEAAGMDVRPITTRQARGLEPALGPRLSAAVHIPNDTQVAPRVFLTALLDALDDCGVEVTKEKITDLEPLYQQFDVVVLAAGLGAQHLSPIPLALRPVRGDILRVQTEPGAVNMVVRGWVNDRPIYIIPRANGEIAIGATSREDERDLPSVEGIYDLLRDAIRVVPGIVDSSLIEANVGVRPGTPDDLPYLGWASDRLIISTGYFRHGILLSSLGAHVTACLIDGTDPGIDLTACAPDRHHNERGTTHGHLH
>NC_016783.1|WP_014302655.1|30622_31291_+|thiamine-phosphate-synthase
MLPTPRWGRDFDPRCYFVTGTGSVDHIVDVARQAARAGAGLIQVRSKPIAARDLYILGREVARAVTEVNPRTRVLIDDRVDVALALMNNGEHIHGVHVGQDDLPVRHVRALLGDNAIIGLTTGTLELVRASRQVAEVIDYIGAGPFRPTPTKDSGRAPVGLAGYPPLVAESLVPVVAIGDVRPEDAADLAATGVAGVAIVRALMNSQDVATDVKLVLKGFAQ
>NC_016783.1|WP_014302654.1|28839_30639_+|phosphomethylpyrimidine-synthase-ThiC
MSAASANSATNPSAWENSEIHPKHSYSPIVSGDLEVPETEIQLDDSPTGPNDPVRIYRTRGPECDPTVGLKPLRAQWIDSREDTEEYAGRERNLADDGRSAQRRGAASLEWKGVKPTPRRAKQGKRVTQMHYARQGIITKEMEFVALREHMDPEFVRSEIARGRAIIPNNINHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLRWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTKRVTGIVSRGGSIMAGWCLAHHKESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSVADANDAAQFAELKTIGELARRAWEYDVQVMIEGPGHVPLNMVQENNELEQKWAHDAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWHDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFADKITDLGIPQVGGDAEAGMAAKSEEFVAQGSQLYSEVRDNAAHA
>NC_016783.1|WP_014307720.1|27147_27765_+|rhomboid-family-intramembrane-serine-protease
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPYSHGLGWLRMVGTVFLHSGPTHLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATVLLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLILIAVNVGYSLLMDGVSLWGHLGGLLTGCVLGIVLVIAQTTRGGKRG
>NC_016783.1|WP_014302662.1|40492_42166_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MASLLEIRWILALDTQGNQISVGIRDIFAGEVQVAYIQGESPAQDYAVMRLLLAIFWRAHSMDIDMDVEPFDFLEWFNKMRRRLARKGKDQVVLDYLDRYADRFELFDVKAPFMQVAGLHVASGEYKHITTIIPEAQDEYFSMRGGKERDSVSTEEAARWLVYVQAFDYNGIKSGAVGDSRVKGGRGYPIGTGWTGMTGGTLVKGEDLLDTLLLNTTLETLNDPEDRPVWERTVYGPDERAVVGENSQPQGPADLATWQSRRIRLIPEGDRVVGVIVCNGDKIPDAGANVLDDPMTPYRFSANKSKKDHDVYYPRPYDVERTMWKALDALVVAETDGGFSAKEKAPKRPKNLASLAELAVQKANVPAVLNVDLVSVEYGPHASSVATTYASRMSIPVVLLLTEAKHLRGKVREIARATTQSAVALGQFSGNLLDAAGGEYAFQPAITDRVLAELEPRFNDWLERLRDISPEQAIQDNESLTDLEKVWQHTARSIIDQHARILLRGAGPKALAGRIQYRDADDHKGRVVSAAGYYRMLQRKLDEVLPLTVRKQEKEGE
>NC_016783.1|WP_014302663.1|42169_42796_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MAENKDALRAAVGATCHRLQEAYLGDRNSARHHSARATLAELRRGATVDIRKNPLGLEKVLFAMAGDFSDRLVGHGDNPSPSEEAAFVALTLFGVHMQSATSPVHIPQVSFASACGRLHSLGTSDSIKPRVDAMLLASQEQARLVHIRSLVTLLRANNIGFDYGLLARDLRALNDPKKRAGIQLRWGRDFAIGHFHNSNSTTNSTQTA
>NC_016783.1|WP_014302664.1|42810_43944_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTLVVDIHALQTVPPSLINRDDMGAPKTAIFGGVPRQRVSSQSWKRTVRRFFEDEIDKSTVGLRSRKLPENIISRAIALGSDLTEDQILDGVRQLFKAAKISLVEPKAPKKGEELPEDAEKYPTTGYLLFLSPYQLDRAAQAVVDKNGEKFTKAEAEDILDTKHSVDMALFGRMLADAPAYNIDASVQVAHAISVHESQPEFDYFTAVDDVVEDAEETGAGMIGTTQMMSSTLYRFATVNVDGLVKNLEDTELAHEAVRMFIRAFAESMPTGKQNSFANNTLPELMYVAVRDTRSVSLVNAFEEPVAAVDGSRRQAAATALAREERDIEEAYGMKPLASFVVALGELGTDFEELAEKVTLTELGEAVIRTLAAQEAK
>NC_016783.1|WP_014302665.1|43948_44653_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSYSLLLLLKGPLQSWGDESRYNTRATGNTPSKSGVIGLLAAAQGRQRTDSIEDLVALDFAVRVDQSGTLLRDYQTAQPWQKAPKANASLVTRHFLSDAAFVAAIGSEDKELLEGLQGHLRQPTYPLFLGRRSCPAPVNLDLGIVDKPVVEALMAHDTWHATSAHQQERSRDVELPIYRDGKPGEHGVPRQDVPLSFAQEHRRYGWRTVVYAGSKSIVNEKGTANDPFFEAVIS
>NC_016783.1|WP_014302666.1|44654_45320_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MATFTKVLINPARRQGRKYLTNPHMLHAAVMHGFPPDCDTSTERILWRLDERGHEHILYVVGPEKPTIDHIVEEAGWDVRPPQSADYDRLLSQLTKGQKWNFELVANPTHTIPVQGGKRGKVVAHSTAAKQLEWLHRKAESMGVSFGTLENSSAQVVGKKTLDFHRSRPNGERGNRVHLVTARFSGQLEVVDADKLRATLIGGVGRAKGYGCGLLTLARGQ
>NC_016783.1|WP_014302667.1|45323_46259_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MSATPSQSPLDRLLLPRMESRLSFLYVERAVINRDGNALTIKDQRGIAHVPATQLAVVLLGPGTKVTYAAMALLGDAGASVVWVGEKGVRYYAHGRPPAKTSRFAEAHARLWSNQRSRLRGARRMYDMRFPGEEISQLSLAQLRGREGARMKKIYAAEAQRTGVVWTRRNYDPQDFESGDPINRALTEGSAALYGIAHAVIVGLGFIPSLGIVHTGTDRAFVYDIADLYKAEISIPAAFEAVAAIPSGDDLNVRARIRDKVVSTRLMQRMVHDLQDLMEIPEEDTYSDVDLMLWSELEVIAAGVNWSTERF
>NC_016783.1|WP_014302668.1|46265_46613_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MIVLVVSAVPAGLRGDLTKWLMEISPGVFVGNPSARIRDLLWERTTELSKDGRALLIYSSNNEQSMEYRTHRHEWEPTDFDGLTLMMRPDNTKPSSYQRRTGWSIARNVRKNRGN
>NC_016783.1|WP_003849883.1|46620_46890_-|cell-division-protein-CrgA
MPKSKINHSSTAYTAGSTANRTPVKINSTGTPLWYKIIMFGLILAGLLWLIVNYLAGQDISFMTELGPWNYGIGFGLFIIGLLMTMGWR
>NC_016783.1|WP_014302669.1|47008_49030_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTDIVLADRYRLGDVIGTGGMSEVYEATDVLLGRKVAVKMLRADLARDVNFRERFRREAQNSGKLNHPAIVAVYDTGETPRAGLNTPYIVMELVNGRTLRDIVCEDGPLTPSQAAHTLIPVCHALQVSHDAGIIHRDIKPANVMITNTGAVKIMDFGIARALDDATSAMTQTSAVIGTAQYLSPEQARGKLADARSDVYALGCVLYETLTGKPPFEGETPFAVAYQHVQEDPVKPSEYIADLSPTAAINVDAVVLTAMAKHPGDRYQTAQEMCADLERLERNAVTDAARHYVTPTSFATQDPASTTVVPVTQVAELDHAEAGAGIGAGAVPAGAVAGSAAVSGSGGAHAAPRSSNRGLRILAAILTVLVLAVGAGFAIDYFGGGPFSQRSTVSIPKLQNSTQQDAVSQLEKLGLQVNVIEEPNPDIPRGKVIRTNPTDGSNVQRNSTVRLTISSGKEITEVPDLSGKNTADAVKILEAAGLLLDPTVREDSSDTVPKGEIIEVSPAAGSQVSRGSKVSITVSTGVETVRVPVITGMKWDQAEGNLTSLGFKPEVVRVDSVEPAGTVVAVPDEGAEVPKGSSVTVQISNGAMFTVPEITRQTIGDAVRILHDAGWKGNASRLIQAAKVPTVAVTDQNLIASQLPTPGTALRKDAPIEIRLYEFNLAALVPPAQH
>NC_016783.1|WP_014302670.1|49026_50535_-|serine/threonine-protein-kinase
MTQSQSPDPALQALVGSDYALQWVVGNGGMSTVWLADDLRNQREVAIKVLRPEFSDNEEFLSRFRNEALASEHIDSDNVVRTYDYREVTDDMGRTLCFIVMEYVRGESLADMLARKGRLEEDLALDVLEQAAHGLSIIHRMGMVHRDIKPGNLLITQNGQVKITDFGIAKAAAAVPLTRTGMVVGTAQYVSPEQAQGRDVTAATDVYSLGVVGYEMLVGQRPFTGDSSVSVAIAHINQAPPAMPTSVSAPARELIGIALRKDPAHRYADGNELALAVSATRMGQRPPQPKSAPLQHIAPQPAPTESTYALGATAQPTTVIPATGQVPAAPAAAAAYPASTVIPAGTPRQEPEKQSSGWGAGIVVGALAALLLGTAAWAASQGMFDDLFDKTSQSSESSVPPPPVTATVTETPTPQITTVVPEPLPTSRPEPTPSETERTPDESDPTLDHQLPSVRPSHNGRPSTQAPHSPTQDADKPAESPAPDTLDSLIENLNKLNQGGAQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_016783_1	1.6\|39595\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39595-39627	33	NZ_CP048637	Rhizobium oryzihabitans strain M15 plasmid p5, complete sequence	265801-265833	6	0.818
NC_016783_1	1.6\|39595\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39595-39627	33	MK359325	Mycobacterium phage Eros, complete genome	44894-44926	7	0.788
NC_016783_1	1.4\|39474\|32\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39474-39505	32	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	72321-72352	8	0.75
NC_016783_1	1.7\|39656\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39656-39688	33	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	588215-588247	8	0.758
NC_016783_1	1.7\|39656\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39656-39688	33	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	933615-933647	8	0.758
NC_016783_1	1.7\|39656\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39656-39688	33	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	933570-933602	8	0.758
NC_016783_1	1.7\|39656\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39656-39688	33	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1254696-1254728	8	0.758
NC_016783_1	1.7\|39656\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39656-39688	33	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1243130-1243162	8	0.758
NC_016783_1	1.14\|40083\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	40083-40115	33	NC_021279	Mycobacteroides abscessus subsp. bolletii 50594 plasmid 2, complete sequence	19957-19989	8	0.758
NC_016783_1	1.14\|40083\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	40083-40115	33	NZ_AP022622	Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1	17981-18013	8	0.758
NC_016783_1	1.14\|40083\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	40083-40115	33	NZ_AP022622	Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1	115208-115240	8	0.758
NC_016783_1	1.14\|40083\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	40083-40115	33	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	733134-733166	8	0.758
NC_016783_1	1.6\|39595\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39595-39627	33	NZ_CP039899	Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence	312577-312609	9	0.727
NC_016783_1	1.6\|39595\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39595-39627	33	NZ_CP039890	Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence	312577-312609	9	0.727
NC_016783_1	1.1\|39291\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39291-39323	33	DQ149023	Synechococcus cyanophage syn9, complete genome	59721-59753	10	0.697
NC_016783_1	1.1\|39291\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39291-39323	33	NC_008296	Synechococcus phage syn9, complete genome	59721-59753	10	0.697
NC_016783_1	1.1\|39291\|33\|NC_016783\|PILER-CR,CRISPRCasFinder,CRT	39291-39323	33	HQ634191	Cyanophage Syn10 genomic sequence	90296-90328	10	0.697

1. spacer 1.6|39595|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048637 (Rhizobium oryzihabitans strain M15 plasmid p5, complete sequence) position: , mismatch: 6, identity: 0.818

ctgaccaagcccgatgcgctcaccgatccagac	CRISPR spacer
atgttcgagcccgatgcgatcaccgatcctgac	Protospacer
 ** .*.*********** ********** ***

2. spacer 1.6|39595|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to MK359325 (Mycobacterium phage Eros, complete genome) position: , mismatch: 7, identity: 0.788

ctgacc--aagcccgatgcgctcaccgatccagac	CRISPR spacer
--gatccggtgccagttgcgctcaccgatccagac	Protospacer
  **.*  . *** * *******************

3. spacer 1.4|39474|32|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 8, identity: 0.75

ctaacccaaaaaccatcctcttcgcccaacac	CRISPR spacer
gtgggcaaaaaaccaccctcttcgcccagcaa	Protospacer
 *.. * ********.************.**

4. spacer 1.7|39656|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

cgcaaacag--gcccgtgaagccgcccgcgctgtc	CRISPR spacer
--ctggctgccgcccgtgaagccgaccacgctgtc	Protospacer
  * ..* *  ************* **.*******

5. spacer 1.7|39656|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.758

cgcaaacag--gcccgtgaagccgcccgcgctgtc	CRISPR spacer
--ctggctgccgcccgtgaagccgaccacgctgtc	Protospacer
  * ..* *  ************* **.*******

6. spacer 1.7|39656|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

cgcaaacag--gcccgtgaagccgcccgcgctgtc	CRISPR spacer
--ctggctgccgcccgtgaagccgaccacgctgtc	Protospacer
  * ..* *  ************* **.*******

7. spacer 1.7|39656|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

cgcaaacag--gcccgtgaagccgcccgcgctgtc	CRISPR spacer
--ctggctgccgcccgtgaagccgaccacgctgtc	Protospacer
  * ..* *  ************* **.*******

8. spacer 1.7|39656|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.758

cgcaaacag--gcccgtgaagccgcccgcgctgtc	CRISPR spacer
--ctggctgccgcccgtgaagccgaccacgctgtc	Protospacer
  * ..* *  ************* **.*******

9. spacer 1.14|40083|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NC_021279 (Mycobacteroides abscessus subsp. bolletii 50594 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.758

ccttgcccgcgccgcggcgcgggttgctcaaaa	CRISPR spacer
cgctgcccgcgccgcggctcgggctgcgcgcac	Protospacer
* .*************** ****.*** *. *

10. spacer 1.14|40083|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022622 (Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1) position: , mismatch: 8, identity: 0.758

ccttgcccgcgccgcggcgcgggttgctcaaaa	CRISPR spacer
cgctgcccgcgccgcggctcgggctgcgcgcac	Protospacer
* .*************** ****.*** *. *

11. spacer 1.14|40083|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022622 (Mycobacteroides abscessus strain JCM 30620 plasmid pJCM30620_1) position: , mismatch: 8, identity: 0.758

ccttgcccgcgccgcggcgcgggttgctcaaaa	CRISPR spacer
cgctgcccgcgccgcggctcgggctgcgcgcac	Protospacer
* .*************** ****.*** *. *

12. spacer 1.14|40083|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 8, identity: 0.758

ccttgcccgcgccgcggcgcgggttgctcaaaa	CRISPR spacer
cctcgcccgcggcgcggcgcgggtgacgctcga	Protospacer
***.******* ************ .* *  .*

13. spacer 1.6|39595|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039899 (Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence) position: , mismatch: 9, identity: 0.727

ctgaccaagcccgatgcgctcaccgatccagac	CRISPR spacer
gccgccaagaccgatgcgctcgccgatctcggc	Protospacer
 . .***** ***********.******. *.*

14. spacer 1.6|39595|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039890 (Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence) position: , mismatch: 9, identity: 0.727

ctgaccaagcccgatgcgctcaccgatccagac	CRISPR spacer
gccgccaagaccgatgcgctcgccgatctcggc	Protospacer
 . .***** ***********.******. *.*

15. spacer 1.1|39291|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to DQ149023 (Synechococcus cyanophage syn9, complete genome) position: , mismatch: 10, identity: 0.697

ggtacggctgtcccatgtgcggttgcttttggc	CRISPR spacer
tacaataatgtccaaagtgcggttgcttttggt	Protospacer
 ..*  . ***** * ****************.

16. spacer 1.1|39291|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to NC_008296 (Synechococcus phage syn9, complete genome) position: , mismatch: 10, identity: 0.697

ggtacggctgtcccatgtgcggttgcttttggc	CRISPR spacer
tacaataatgtccaaagtgcggttgcttttggt	Protospacer
 ..*  . ***** * ****************.

17. spacer 1.1|39291|33|NC_016783|PILER-CR,CRISPRCasFinder,CRT matches to HQ634191 (Cyanophage Syn10 genomic sequence) position: , mismatch: 10, identity: 0.697

ggtacggctgtcccatgtgcggttgcttttggc	CRISPR spacer
tacaataatgtccaaagtgcggttgcttttggt	Protospacer
 ..*  . ***** * ****************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

245650 : 289890

uncultured_Mediterranean_phage(15.38%)

integrase,protease,holin,transposase

attL 239255:239271|attR 291318:291334

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
239255:239271	attL	NA	NA	NA	NA
WP_014301302.1\|245650_246835_+\|protease	MarP family serine protease	NA	NA	NA	NA
WP_014302818.1\|246831_247770_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_003850430.1\|247857_248358_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_010934200.1\|248485_249139_+	hypothetical protein	NA	NA	NA	NA
WP_003850437.1\|249076_249934_-	HAD family hydrolase	NA	NA	NA	NA
WP_014302819.1\|250404_251442_+	hypothetical protein	NA	NA	NA	NA
WP_014302820.1\|251434_252532_+	TadA family conjugal transfer-associated ATPase	NA	NA	NA	NA
WP_014302821.1\|252528_253275_+	type II secretion system F family protein	NA	NA	NA	NA
WP_014301309.1\|253274_253853_+	type II secretion system F family protein	NA	NA	NA	NA
WP_044026289.1\|253876_254074_+	DUF4244 domain-containing protein	NA	NA	NA	NA
WP_010934206.1\|254070_254346_+	hypothetical protein	NA	NA	NA	NA
WP_014302822.1\|254342_254669_+	flp pilus-assembly TadE/G-like family protein	NA	NA	NA	NA
WP_014302823.1\|254658_256995_-	DEAD/DEAH box helicase	A0A1B1IUF6	uncultured_Mediterranean_phage	1.0e-08	27.7
WP_003850453.1\|257264_257468_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.1e-15	62.3
WP_014302824.1\|257641_258259_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	1.3e-08	30.2
WP_014302825.1\|258255_258963_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-12	30.0
WP_014302826.1\|258959_260207_+	MFS transporter	NA	NA	NA	NA
WP_014302827.1\|260203_261691_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014302828.1\|261691_263452_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_014301318.1\|263429_264923_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_014302829.1\|265063_267958_+	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	2.9e-98	36.1
WP_016830087.1\|268107_268716_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_014301321.1\|269144_271121_-	oligopeptide transporter, OPT family	NA	NA	NA	NA
WP_014302831.1\|271207_273244_-	exo-alpha-sialidase	NA	NA	NA	NA
WP_014302832.1\|273350_274250_+	DUF4862 family protein	NA	NA	NA	NA
WP_014302833.1\|274266_275793_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	1.8e-19	31.7
WP_014301324.1\|275791_277057_+	DNA polymerase III subunit delta'	S5WKH4	Pseudomonas_phage	3.5e-08	28.4
WP_080563650.1\|277509_277914_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_003850484.1\|277953_278361_+	hypothetical protein	NA	NA	NA	NA
WP_014302834.1\|278364_279129_-\|integrase	tyrosine-type recombinase/integrase	A0A1W6JRD7	Corynebacterium_phage	4.0e-76	60.3
WP_014302835.1\|279354_279564_-	hypothetical protein	A0A1W6JRD7	Corynebacterium_phage	4.7e-19	66.7
WP_014302836.1\|279877_281227_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	8.0e-35	37.4
WP_014302837.1\|281658_281904_-	virulence RhuM family protein	NA	NA	NA	NA
WP_014302838.1\|282167_282692_+	hypothetical protein	NA	NA	NA	NA
WP_003850495.1\|282698_283025_+	hypothetical protein	NA	NA	NA	NA
WP_044026290.1\|283564_284551_-	Fic family protein	D7RWK9	Brochothrix_phage	3.7e-13	35.1
WP_014306410.1\|284589_285288_+	alpha-ketoglutarate-dependent dioxygenase AlkB	NA	NA	NA	NA
WP_014302842.1\|285398_286151_-	S1 family peptidase	NA	NA	NA	NA
WP_014302843.1\|286757_287267_-	hypothetical protein	NA	NA	NA	NA
WP_158307792.1\|287749_287950_-\|transposase	transposase	Q6H9S3	Enterobacteria_phage	1.8e-07	44.0
WP_014302848.1\|289521_289890_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1B3AZE5	Gordonia_phage	1.0e-13	49.4
291318:291334	attR	NA	NA	NA	NA

DBSCAN-SWA_2

646617 : 704953

Bacillus_phage(16.67%)

integrase,protease,transposase,tRNA

attL 639908:639928|attR 712776:712796

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
639908:639928	attL	NA	NA	NA	NA
WP_014303067.1\|646617_647121_-\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_010934497.1\|647166_647790_+	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	1.7e-08	28.5
WP_044026306.1\|647786_648038_+	mycothiol system anti-sigma-R factor	NA	NA	NA	NA
WP_014303068.1\|648042_648387_-	DUF4288 domain-containing protein	NA	NA	NA	NA
WP_004567132.1\|648725_648986_-	WhiB family transcriptional regulator	A0A2P1N2X5	Mycobacterium_phage	2.0e-11	45.1
WP_050806154.1\|649618_650080_+	hypothetical protein	NA	NA	NA	NA
WP_004567135.1\|650073_651336_-	hypothetical protein	NA	NA	NA	NA
WP_014303070.1\|651332_652643_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.3e-42	30.0
WP_004567139.1\|652901_653129_+	DUF3107 domain-containing protein	NA	NA	NA	NA
WP_014303071.1\|653131_654010_+	DUF3152 domain-containing protein	NA	NA	NA	NA
WP_014303072.1\|654032_654890_+	TIGR02569 family protein	NA	NA	NA	NA
WP_014303073.1\|654893_658076_+	ATP-dependent helicase	NA	NA	NA	NA
WP_044026307.1\|658069_661300_+	ATP-dependent helicase	A7KV33	Bacillus_phage	5.1e-19	22.9
WP_014301551.1\|661344_662433_+	potassium channel family protein	NA	NA	NA	NA
WP_014301552.1\|662464_663148_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_014303075.1\|663140_665192_+	ATP-dependent DNA helicase UvrD2	S5MMD7	Bacillus_phage	1.7e-44	27.5
WP_014303076.1\|665136_666030_-	hypothetical protein	NA	NA	NA	NA
WP_010934510.1\|666065_666587_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_014301554.1\|666583_667975_-\|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
WP_044026308.1\|668055_669108_+	PDZ domain-containing protein	NA	NA	NA	NA
WP_014303078.1\|669119_669818_-	hypothetical protein	NA	NA	NA	NA
WP_014303079.1\|669868_670372_-	hypothetical protein	NA	NA	NA	NA
WP_014303080.1\|670544_673508_+	UPF0182 family protein	NA	NA	NA	NA
WP_014303081.1\|673967_676565_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.1e-92	40.8
WP_148263743.1\|676557_677751_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_014303083.1\|677760_680955_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	8.8e-24	23.5
WP_014303085.1\|681713_682784_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_014303086.1\|682786_683743_-	DUF418 domain-containing protein	NA	NA	NA	NA
WP_010934521.1\|684373_685855_+	methylmalonyl-CoA carboxytransferase subunit 5S	NA	NA	NA	NA
WP_014303088.1\|685867_687424_+	acyl-CoA carboxylase subunit beta	NA	NA	NA	NA
WP_003850577.1\|687437_687701_+	hypothetical protein	NA	NA	NA	NA
WP_014303089.1\|687725_688094_+	biotin/lipoyl-binding protein	NA	NA	NA	NA
WP_014303090.1\|688296_689388_+	hypothetical protein	NA	NA	NA	NA
WP_014303091.1\|689406_690195_-	histidinol-phosphatase	NA	NA	NA	NA
WP_014303092.1\|690250_691066_-	inositol monophosphatase family protein	NA	NA	NA	NA
WP_010934526.1\|691245_692355_+	peptide chain release factor 2	NA	NA	NA	NA
WP_014303093.1\|692351_693950_-	AbgT family transporter	NA	NA	NA	NA
WP_014303094.1\|694128_694818_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	9.1e-27	38.2
WP_003850598.1\|694834_695737_+	ABC transporter permease	NA	NA	NA	NA
WP_014303095.1\|695843_696335_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-36	52.2
WP_014303096.1\|697165_697507_-	cupin domain-containing protein	NA	NA	NA	NA
WP_014303097.1\|697540_698344_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_157892472.1\|698710_698971_-	hypothetical protein	NA	NA	NA	NA
WP_014303099.1\|699119_699581_+	hypothetical protein	NA	NA	NA	NA
WP_044026370.1\|700168_700783_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_014301568.1\|700783_701149_+	hypothetical protein	NA	NA	NA	NA
WP_158307792.1\|701211_701412_-\|transposase	transposase	Q6H9S3	Enterobacteria_phage	1.8e-07	44.0
WP_014302848.1\|702983_703352_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1B3AZE5	Gordonia_phage	1.0e-13	49.4
WP_094078631.1\|703946_704126_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_111936218.1\|704150_704735_+\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_014303104.1\|704737_704953_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-13	51.6
712776:712796	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1822758 : 1884426

Agrobacterium_phage(18.18%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044026335.1\|1822758_1825467_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	9.4e-136	37.4
WP_014303749.1\|1825561_1826542_-	malate dehydrogenase	NA	NA	NA	NA
WP_014303750.1\|1827024_1827777_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_014303751.1\|1827813_1829106_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.5e-131	54.2
WP_014303752.1\|1829252_1831778_-	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	2.8e-65	30.2
WP_003852475.1\|1831872_1832502_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	3.6e-38	44.0
WP_014303753.1\|1832519_1833119_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.5e-41	46.7
WP_014303754.1\|1833284_1834631_-	trigger factor	NA	NA	NA	NA
WP_003852480.1\|1835458_1835695_+	hypothetical protein	NA	NA	NA	NA
WP_014303755.1\|1835841_1836597_+	hypothetical protein	NA	NA	NA	NA
WP_003852484.1\|1836673_1837147_-	ribose-5-phosphate isomerase	NA	NA	NA	NA
WP_014303756.1\|1837178_1837799_-	DsbA family protein	NA	NA	NA	NA
WP_014303757.1\|1837920_1840539_+	aminopeptidase N	A0A0P0IY26	Acinetobacter_phage	1.8e-43	27.5
WP_010935342.1\|1840794_1841811_+	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_010935343.1\|1841822_1842215_+	globin	NA	NA	NA	NA
WP_014303758.1\|1842211_1842832_-	hypothetical protein	NA	NA	NA	NA
WP_010935345.1\|1842841_1843285_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_003852495.1\|1843411_1845082_-	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	1.7e-47	28.2
WP_003852496.1\|1845179_1845668_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_014303759.1\|1845851_1847888_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_014303760.1\|1848114_1850400_+	carbon starvation protein A	NA	NA	NA	NA
WP_003852501.1\|1850420_1850621_+	YbdD/YjiX family protein	NA	NA	NA	NA
WP_014303761.1\|1852092_1853298_-	MFS transporter	NA	NA	NA	NA
WP_014303762.1\|1853703_1854735_+	oxidoreductase	NA	NA	NA	NA
WP_003852523.1\|1854794_1855595_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_014303763.1\|1855613_1856243_+	oligoribonuclease	M4M9I5	Vibrio_phage	4.3e-23	38.6
WP_014303764.1\|1856423_1857254_+	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_014303765.1\|1857254_1858508_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_014302249.1\|1859429_1859879_+	isochorismatase family protein	NA	NA	NA	NA
WP_003852591.1\|1860199_1860475_-	DUF3618 domain-containing protein	NA	NA	NA	NA
WP_010935369.1\|1860563_1861037_+	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_003852595.1\|1861037_1861682_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_003852597.1\|1861678_1862062_-	holo-ACP synthase	NA	NA	NA	NA
WP_014303767.1\|1862096_1871030_-	type I polyketide synthase	NA	NA	NA	NA
WP_014303768.1\|1871208_1871586_-	hypothetical protein	NA	NA	NA	NA
WP_014303769.1\|1871891_1872263_+	hypothetical protein	NA	NA	NA	NA
WP_003852603.1\|1872290_1872647_+	DUF3817 domain-containing protein	NA	NA	NA	NA
WP_014303770.1\|1872643_1873267_-	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	Q66YC8	Euphorbia_ringspot_virus	2.5e-07	41.8
WP_003852605.1\|1873263_1873989_-	ribonuclease PH	NA	NA	NA	NA
WP_044026337.1\|1873999_1874767_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_014303772.1\|1874819_1875617_-	glutamate racemase	NA	NA	NA	NA
WP_014303773.1\|1875613_1876186_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_014303774.1\|1876182_1877115_-	P1 family peptidase	NA	NA	NA	NA
WP_014303775.1\|1877114_1877651_-	DUF2017 domain-containing protein	NA	NA	NA	NA
WP_014303776.1\|1877667_1878009_-\|protease	ATP-dependent Clp protease adapter ClpS	NA	NA	NA	NA
WP_003852615.1\|1878070_1879384_+	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_014303777.1\|1879415_1881383_+	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	6.8e-67	29.8
WP_003852618.1\|1881384_1881912_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014302836.1\|1883076_1884426_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	8.0e-35	37.4

DBSCAN-SWA_4

2053206 : 2098103

Bacillus_phage(14.29%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014303899.1\|2053206_2054586_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	6.0e-38	33.7
WP_014303902.1\|2056276_2056426_+	hypothetical protein	NA	NA	NA	NA
WP_014303904.1\|2057022_2058396_+	dipeptidase	NA	NA	NA	NA
WP_014303905.1\|2058562_2059723_+	DUF2029 domain-containing protein	NA	NA	NA	NA
WP_014303906.1\|2059665_2060745_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_014303907.1\|2060741_2061296_-	LytR C-terminal domain-containing protein	NA	NA	NA	NA
WP_016830141.1\|2061298_2061502_-	DUF3263 domain-containing protein	NA	NA	NA	NA
WP_014303908.1\|2061500_2062064_+	peptide deformylase	A0A2I7R224	Vibrio_phage	1.0e-12	38.2
WP_014303909.1\|2062080_2062968_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014303910.1\|2062972_2063680_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_014303911.1\|2063676_2065110_+	cardiolipin synthase	NA	NA	NA	NA
WP_003852994.1\|2065813_2066551_-	multidrug ABC transporter permease	NA	NA	NA	NA
WP_014303914.1\|2066534_2067464_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.4e-30	37.7
WP_014303915.1\|2067465_2068722_+	hypothetical protein	NA	NA	NA	NA
WP_014303916.1\|2068718_2069666_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_014303917.1\|2069662_2071825_+	serine/threonine protein kinase	A0A1V0SBL0	Catovirus	4.6e-08	24.0
WP_003853004.1\|2071844_2073044_-	acetate kinase	NA	NA	NA	NA
WP_014303918.1\|2073044_2074412_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_014303919.1\|2074674_2076033_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014303920.1\|2076044_2076941_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_003853372.1\|2076972_2077473_+	phosphoribosyltransferase	NA	NA	NA	NA
WP_014303921.1\|2077504_2078392_+	hypothetical protein	NA	NA	NA	NA
WP_014303922.1\|2078388_2079819_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_003853379.1\|2079819_2079987_-	hypothetical protein	NA	NA	NA	NA
WP_014303923.1\|2080201_2081491_-	adenylosuccinate synthase	A0A160ER07	Powai_lake_megavirus	1.5e-67	35.4
WP_016830150.1\|2081673_2081826_+	hypothetical protein	NA	NA	NA	NA
WP_193345910.1\|2082130_2082967_+	hypothetical protein	NA	NA	NA	NA
WP_014303926.1\|2082963_2084091_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_014303927.1\|2084204_2085338_+	hypothetical protein	NA	NA	NA	NA
WP_014303928.1\|2085429_2086554_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_014303929.1\|2086582_2086756_+	hypothetical protein	NA	NA	NA	NA
WP_014303930.1\|2087023_2087935_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_014302413.1\|2088223_2089336_+	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	NA	NA	NA	NA
WP_094078774.1\|2089665_2090109_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_016830156.1\|2090899_2091427_-	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_080563661.1\|2091837_2092095_-\|transposase	transposase	A0A2P1JR32	Mycobacterium_phage	1.9e-14	54.7
WP_016830159.1\|2092770_2093487_-	hypothetical protein	NA	NA	NA	NA
WP_016830160.1\|2093707_2093857_-	hypothetical protein	NA	NA	NA	NA
WP_094078637.1\|2093945_2094188_-	recombinase family protein	NA	NA	NA	NA
WP_016830164.1\|2096490_2096694_+	hypothetical protein	NA	NA	NA	NA
WP_014303942.1\|2096841_2097063_+	hypothetical protein	NA	NA	NA	NA
WP_080563662.1\|2097366_2097546_-\|transposase	transposase	NA	NA	NA	NA
WP_014303944.1\|2097499_2097646_-\|transposase	transposase	A0A0N7C1X7	Escherichia_phage	1.6e-05	62.9
WP_029589643.1\|2097926_2098103_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

2174338 : 2180706

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014304000.1\|2174338_2175544_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-50	36.3
WP_014304001.1\|2175549_2176113_-	dCTP deaminase	I4AZP2	Saccharomonospora_phage	6.6e-76	72.6
WP_010935613.1\|2176407_2177187_-	hypothetical protein	NA	NA	NA	NA
WP_014304002.1\|2177183_2178017_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.3e-26	35.2
WP_010935615.1\|2178013_2178346_-	PLDc N-terminal domain-containing protein	NA	NA	NA	NA
WP_014304003.1\|2178345_2179038_-	hypothetical protein	NA	NA	NA	NA
WP_044026344.1\|2179037_2179364_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_014304004.1\|2179684_2180062_-	HNH endonuclease	A0A2H4PHY5	Pseudomonas_phage	5.5e-10	46.5
WP_158307794.1\|2179943_2180390_-	phage antirepressor KilAC domain-containing protein	A0A1Q1PVZ8	Staphylococcus_phage	2.7e-16	51.2
WP_014304006.1\|2180460_2180706_-	Bro-N domain-containing protein	E7DUM4	Liberibacter_phage	1.1e-19	59.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage