CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017770	Solitalea canadensis DSM 3403, complete sequence	10 crisprs	csa3,DEDDh,cas3,WYL	1	2	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017770_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_1

557489-557596

Orphan

Consensus_repeat	Method
GCGTCTTCGCGCCTTTGCGGTTTGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_1

>merge|NC_017770|1|557489-557596|CRISPRCasFinder
GCGTCTTCGCGCCTTTGCGGTTTGAAAATAATAGACACTGAGACGCTACGATTTTTTAGTCTTAAACTGGGATAAATCTTAGCGTCTTAGCGCCTTTGCGGTTTGAAA

>NC_017770|1|1|557489-557596|CRISPRCasFinder
GCGTCTTCGCGCCTTTGCGGTTTGAAA	ATAATAGACACTGAGACGCTACGATTTTTTAGTCTTAAACTGGGATAAATCTTA
GCGTCTTAGCGCCTTTGCGGTTTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014678809.1\|551805_556158_+\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|226220
NC_017770.1\|WP_014678806.1\|549685_550204_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678802.1\|545873_546350_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678810.1\|556207_557407_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_017770.1\|WP_014678812.1\|559838_561848_+\|1,4-alpha-glucan-branching-protein-GlgB	unknown	unknown	gnl\|CDD\|235445
NC_017770.1\|WP_014678808.1\|551270_551654_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678805.1\|548328_548628_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367663
NC_017770.1\|WP_014678818.1\|565438_566065_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234701
NC_017770.1\|WP_014678803.1\|546464_547667_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223475
NC_017770.1\|WP_014678807.1\|550349_551117_-\|Zn-ribbon-containing-protein	unknown	unknown	gnl\|CDD\|370804
NC_017770.1\|WP_014678819.1\|566067_566397_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|223734
NC_017770.1\|WP_014678811.1\|557675_559649_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319847
NC_017770.1\|WP_081480021.1\|544015_544261_-\|TPM-domain-containing-protein	unknown	unknown	gnl\|CDD\|377378
NC_017770.1\|WP_014678821.1\|566930_567260_+\|multidrug-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NC_017770.1\|WP_014678817.1\|564993_565422_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678820.1\|566472_566931_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678813.1\|561877_562222_+\|DUF1801-domain-containing-protein	unknown	unknown	gnl\|CDD\|378058
NC_017770.1\|WP_014678816.1\|563804_564932_+\|hydrolase	unknown	unknown	gnl\|CDD\|224594
NC_017770.1\|WP_014678815.1\|563515_563701_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678801.1\|544678_545860_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014678809.1\|551805_556158_+\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
NC_017770.1\|WP_014678811.1\|557675_559649_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319847	cd07548, P-type_ATPase-Cd_Zn_Co_like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis CadA which appears to transport cadmium, zinc and cobalt but not copper out of the cell. Bacillus subtilis CadA/YvgW appears to transport cadmium, zinc and cobalt but not copper, out of the cell. Functions in metal ion resistance and cellular metal ion homeostasis. CadA/YvgW is also important for sporulation in B. subtilis, the significant specific expression of the cadA/yvgW gene during the late stage of sporulation, is controlled by forespore-specific sigma factor, sigma G, and mother cell-specific sigma factor, sigma E. This subfamily also includes Helicobacter pylori CadA an essential resistance pump with ion specificity towards Cd(2+), Zn(2+) and Co(2+), and Zn-transporting ATPase, ZiaA(N) in Synechocystis PCC 6803. Transcription of ziaA is induced by Zn under the control of the Zn responsive repressor ZiaR. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_017770.1\|WP_014678810.1\|556207_557407_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.55068e-37
NC_017770.1\|WP_014678812.1\|559838_561848_+\|1,4-alpha-glucan-branching-protein-GlgB	gnl\|CDD\|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NC_017770.1\|WP_014678805.1\|548328_548628_-\|hypothetical-protein	gnl\|CDD\|367663	pfam03795, YCII, YCII-related domain. The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat. A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function. This family also now includes the family formerly known as the DGPF domain (COG3795). Although its function is unknown it is found fused to a sigma-70 factor family domain in CC_1329. Suggesting that this domain plays a role in transcription initiation (Bateman A per. obs.). This domain is named after the most conserved motif in the alignment.	2.67342e-11
NC_017770.1\|WP_014678818.1\|565438_566065_+\|hypothetical-protein	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0.00718244
NC_017770.1\|WP_014678803.1\|546464_547667_-\|hypothetical-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	0.0028862
NC_017770.1\|WP_014678807.1\|550349_551117_-\|Zn-ribbon-containing-protein	gnl\|CDD\|370804	pfam10071, DUF2310, Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310). Members of this family of proteobacterial zinc ribbon proteins are thought to bind to nucleic acids, however their exact function has not as yet been defined.	3.3948e-119
NC_017770.1\|WP_014678819.1\|566067_566397_+\|cupin-domain-containing-protein	gnl\|CDD\|223734	COG0662, {ManC}, Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism].	3.64418e-09
NC_017770.1\|WP_081480021.1\|544015_544261_-\|TPM-domain-containing-protein	gnl\|CDD\|377378	pfam04536, TPM_phosphatase, TPM domain. This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II.	1.08346e-12
NC_017770.1\|WP_014678821.1\|566930_567260_+\|multidrug-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	1.50753e-28
NC_017770.1\|WP_014678813.1\|561877_562222_+\|DUF1801-domain-containing-protein	gnl\|CDD\|378058	pfam08818, DUF1801, Domain of unknown function (DU1801). This large family of bacterial proteins is uncharacterized. They contain a presumed domain about 110 amino acids in length.	1.62194e-14
NC_017770.1\|WP_014678816.1\|563804_564932_+\|hydrolase	gnl\|CDD\|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	4.82523e-42

>NC_017770.1|WP_014678810.1|556207_557407_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKRNYLYITILMVLVSLSGCGSKANKPDAETKTEEGTQAEHGHETEVEFTALQYKAAGIQLGTIEERELGLTIKANGVLDVPPQNLVSISVPFGGFLRSTDLLQGTRVKKGQLIATIQNPDYIQFQQDYLESKSQLEFLEAEYKRQEELAAANINAKKTLQKAKAEYLSARARVQGLKARLQLININPSSIENGNFKSTVSVYSPITGYVTAVNVNVGSFVNPTDVLFKIVDTEHLHAELTIYEKDMPKLKIGQKVRVYLSNDKKERVAKVHLIGREVSNDRTITVHCHLDEEDISLIPGTFLSGIVETGASKVASLPDEAIVQNGESKVIFVSEGSRKEGNEVVQLFKAVEVTTGVSDGGFTEIIVPEGMNKKASVVLKGAFDILSKMNSGEEAGHAH
>NC_017770.1|WP_014678809.1|551805_556158_+|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MLDKIIYFSIKNKLVIGLFTLALIAVGVYSLTRLPIDAVPDITNNQVQVITYAPSQSAPDIERLVTYPIEQTMATIPGIEEVRSFSRFGLSVVTVVFKENVDVYWARQQISERLGLAKELIPDGVGTPEMAPLTTGLGEIYQYAIHPKKGYEDKYDATELRTIQDWIVKRQLLGTPGVAEVSSFGGNVKEYEIAINSDKLRSLNVSIDELFTALKKNNQNTGGAYIDRKPNAYFIRSEGLINNLDDIGKIVVRTNSNGTPVLIRDVAEVKFGYGARYGAMTYNDKNEVVGAVVMMLKGENSSKVIKNVKERITQISKTLPEGLEIEPFLDRTKLVDKAINTVSKNLAEGALIVIFVLVLLLGNLRAGLVVASVIPLAMLFAITLMNFFGVSGNLMSLGAIDFGLIVDGAVIIVEATMHHLGLRTLDRRLTQGEMDKEVFESTRKIRNSAAFGEIIILIVYLPILALVGVEGKMFKPMAQTVSFAILGAFILSLTYVPMMSALCLSKKIEHKRTIADWIMEFFHRIYNPIIRWALHKRAFVIITAIVLFIGSLFMFSRLGAEFIPSLDEGDFAVETRVMTGGSISQTVEVAQKSAKVLLANYPEIKEVVGKIGSSEIPTDPMPVEACDLMVILKDRSEWTSADSKDELAEKMQKTLEDNIPGVAYGFQQPIQMRFNELMTGARQDVVLKVYGEDLDMLARYASQIGKVAAGTEGAKDLYVEKVSGLPQIVINYNRDRIAQFGLSIAEVNQAINTAFAGQAAGFVYEGEKRFALTVRLAKQSRQSIEDVKNLYVSSSDGRQIPLEQVADVEMQIGPSQIQRDDAKRRIIVGFNVRGRDVESIVNEVKSKIEKDVKFAPGYYVTYGGTFKNLEEARLRLSIAVPVALLLILLLLFFTFKSIKHSLLIFTAIPLSAIGGVLALWLRDMPFSISAGVGFIALFGVAVLNGIVLIAEFNRLKKEGLTDIKEIIFRGTSTRLRPVIMTAAVASLGFLPMALSGSEGAEVQRPLATVVIGGLITATILTLVVLPVLYMYFEKIKIRTTANVIGGLVGLLFLIPTKTNAQQLSLDSAIKVAIERNHVIKTASLGIDQQKRLKGTSIDLPKTEVSLMAGQYNGPSKQDKNITISQSLPFPTVFSANAALANETIKSAEFKKTVSINDLTLQVKQTYYTLQYLLDTKLLFIQQDSLYAQFLRASDLRYKTGESTLLEKSAAETQRNEIHNQLRINEADIDIELNKFNVLLNGAGYSVVHVPAKERVYGFTEQSAAITYNPNLSYFKQQVNIAGQQKRVEQNRMLPDLTLGYFNQSLIGYHDVNGQAQYFGASDRFQGFQVGVAIPLWFKSQSSKIKAADIQKQIAQNEFELAEKQLSGSFTQSYAQYQKNLKSIAYYRESALPNAELIIKQSQEAYRLGEIPYSEYLLNMRQALSIKESYLKSLLELNQSVIMLEYLTGKN
>NC_017770.1|WP_014678808.1|551270_551654_+|hypothetical-protein
MRKAYSILLLFFYLFSTTELHELVKIPILVEHYYHHSAANNNESLITFINEHYFSGDIHDEDYSQDKKLPFKSNDNCVLATTSVAVNPELFTIVKPAIFSIERNYKVEKNIHFSSDYLSSIWQPPKA
>NC_017770.1|WP_014678807.1|550349_551117_-|Zn-ribbon-containing-protein
MYIQEISLEINSGVDIVLIEDQFDILMSHYRGSGQTQGKIESQYTSGNKIISLPYTHEDESLHKNYNNRYVNRQTLKIEELCASKLQFSTVGKSYHDYESACKCAKPAFYILITNYLSISSPVKCGNCYMPVPLYKLPEYYDYGYMPILSWESNYISCDTLQMNSEVGERWGLNQMQNFDSSLSKQGREICKKIEELTNTPTYYYLHNYRKIKGDQLKTPCPSCNKKWSLKKQLHSVFDFKCDYCRLVSSVSPNS
>NC_017770.1|WP_014678806.1|549685_550204_+|hypothetical-protein
MTRFFKVLLFVFAFFGSAPILYAQQIKDGETLNLNGLDVTFRILNKEVTDVKGVSFDKYKVSATVKNNTGKSYNARLTTYPSVEAIAASKIVELNCINATGAKLTSKKLDVNMNEHRIVVTYLTMNKEGKTVNSTMTITVGYYLDPGQTVQGEANFIVPKGETPQVNVHTLQ
>NC_017770.1|WP_014678805.1|548328_548628_-|hypothetical-protein
MSEKKHFYLKLVASRPTFAMDMNNEEKAIMQQHVAYWMDLMNQGKVIVFGPVFDPNGAFGVGIVEASSEEEVKTLIDNDPASKINHYEVYPMKAVLPAK
>NC_017770.1|WP_014678803.1|546464_547667_-|hypothetical-protein
MKTQEQLQDSVESPGSNKKKGLANPSGRGILNLFSVCMFIIGALIVIFFGTTLTGKITILLWMLACLFIGAITGFLFGIPKILQSNQAKIPESDNAEVTKIDLSKQAPIYQQQVNTNLTEISDWLTKIIVGLGLVNLTRIPPFLNNAATILASGLSEPQITPSKMAIASAYGIIIAYTIFGFLFAYITTRLYLAVLFSEADQRTLLSIAQKTERTAQKTEEIAQKAKEAAGAAQSALQKAEFALITSPDTSLHGSSLENLLQSAANYNEIRNTMKPGPARTSKMTEVVKGMMAIISLIETYDIDAALKDRNDGKRLIGYVWLNVKPNEEYLGELVDAIATDPTAFGQYWGIQALSKIIKHRTSEKMDPTVFNKLKSYYNRLDKGIDREYELARILPELKK
>NC_017770.1|WP_014678802.1|545873_546350_+|hypothetical-protein
MRKHILYLLPLITTMLFMMIACNSTQLAVSGPVADGWQDSIANNTSIIKIITHLDNKSLRRTALELCEKHRILLDVESSSSQHWYTLAKVKPLERLSMQFQDSVMLLSAEKQLYGLNGNYWDKLRLNTSEWHLSIKQIELLMKGFPKGKIVYNKPVGN
>NC_017770.1|WP_014678801.1|544678_545860_+|hypothetical-protein
MKSLLPILFMLLSFQVYAQTKKNPPIKNSTDVEKGYRIIYDYKNGTIETFKNGEKVQQLRPIVGRIVQISVKNYNPYTDSIIAAVSFSDRNTEDAAAFKGLIAKNAKLEEKEGEEPGKGLDQSLDSAKLKKVKLELDEAYGKAQLMSIDALESYVATTSIKIKGELGVEKVTVDQIQEKLKDSERNKSVVKDLVAGVVVAYQRLISFKVLVAVPVQIQNKDVISITFNNHKNPAIAPLQFDYLVQGGVKIDFSTGIFINGLVDEDYYLKSDGQGGGIITAKDNGNYNLGFGILSHLYSRTGGRVNFGLTTGLLTDATANLRLLGGGSILLGSESRWVISGGAVLGKAKKLTNGYNAGDTFAGDEAEIPYTDKFSTKWFVGITYNFGGFNIGKK
>NC_017770.1|WP_081480021.1|544015_544261_-|TPM-domain-containing-protein
MITAFEKETTIEIAIVTIDSLHASKEKFDDFTLRIANKWGVGKQDKNNGILIGLYVKECHTSFQMISVHIVHYRQMVLSCL
>NC_017770.1|WP_014678811.1|557675_559649_+|cadmium-translocating-P-type-ATPase
MRHPYFHQGGHDDCCSIEHNHVKETTKQVQDTSLTSPYKEYIPSIISFVLLMIGLSLDHFVKPDFFKSYVRLTWYLIAYLPVAWSVILTGLKLIRKGEVFTEFFLMTVATLGAFYIGEYPEGVAVMLFYSVGELFQGAAVKRAKGNIKALLDVRPDSATVIRNDVATIVHPEKVGVGEIISLKPGEKVPLDGTIIDGYSSFNTAALTGESKPKTIRAAETVLAGMINIDRAVMVRVTKKFTESSLARILDMVQNASARKAQTELFIRKFAKIYTPIVVYLALAVIFLPYFFVSDYVFNDWLYRGLIFLVISCPCALVISIPLGYFGGIGAASRNGILFKGSNYLDQVTKLTTVVMDKTGTLTKGVFNVQEVISANGDKQKLINYAAALESHSTHPAAKAIISYANGSVQSASLKAMNVQEIAGHGLKGEVNGSVVLAGNAKLLAKHAIAYPKELDAVVDTVVAVAIDGNYAGYFTIADELKEDAQQAVKDLHNAGVKELVMLSGDKSSVVQKVIKTLGIEKGFGDLLPEGKVQKVEEIKSDRSKVVAFVGDGINDAPVLALSDVGIAMGGLGSGAAIETADVVIQTDHPSKIATAINIGKATQRIVWQNIGLAMGIKIIVLILGAGGVASMWEAVFADVGVALLAILNAIRIQRMKF
>NC_017770.1|WP_014678812.1|559838_561848_+|1,4-alpha-glucan-branching-protein-GlgB
MHYSPSVLLYSRFSDFDIGLFKAGKHFRLYDKLGSHVVEHEGTTGTYFAVWAPNADAVSVIGNFNGWNNEAHYLGARWDGSGIWEGFIPNIGQGEAYKYFIRSNSGGYFERADPYALYCEEPPRTASIVWNTWYEWQDQEWMNRRPQFNALDKPISVYEVHLASWRRDPSNPDRFLSYRELARDLVEYVTHMGFTHVEFMPVMEHPFLGSWGYQVTGYFAPTSRFGSPQDFMFLIESLHRAGIGVYLDWVPSHFPGDAHGLYNYDGSHLYEHADPRQGFHPDWSSYIFNYGRNEVRSFLISNALFWFDRYHADGLRVDAVASMLYLDYSRKEGEWVPNQYGGRENLDAVSFLKELNEVAYGNYGDIQMIAEESTSWPGVSHPTWQGGLGFGMKWMMGWMNDTLRYFAKEPIYRRYHQQELTFSTVYAFTENFMLPLSHDEVVHGKGALVSKMPGDEWQRFANLRLLYAFMYTHPGTKLLFMGGEFGQTSEWSHDYSLDWHLTQYEPHKGVENMMCDLNRLYKNEPALYDFNFAGYGFEWIDQSDSENCVLVYCRKGHHWQEYVVVVANLTPVARHDYRIGLPHNGTWSEIFNSDKHDYWGSGVVNHYPKEAEMESWQGKAQSISISLPPSGITVWKLKEHPDVSNSNYSENNIKEEKKKKAPKGLSDGK
>NC_017770.1|WP_014678813.1|561877_562222_+|DUF1801-domain-containing-protein
MLREIDQFYLHQNDPVRSCLIALRNYILTFNDQFTETWKYKMPCYCYKGKHFCYLWIDKKTREPYVLLVEGRQIDHPDLEAGDRSRMKILRIKPNEDLPVETLNTIFEQLVRLV
>NC_017770.1|WP_014678815.1|563515_563701_+|hypothetical-protein
MIRLTFKTSAFRNDNLKVKFIKLCKSTQLLIASFVSTGLKADTTVVESVKTIASLSTINKT
>NC_017770.1|WP_014678816.1|563804_564932_+|hydrolase
MQKTLIVLLLVFLQSFGAPAQSIQKPVQAKDGIPIGNSTVLDAGIIAKMEAAITDGTFPNIHSVLIAKSNKLVYEHYWPGKDEIWGNYKGIVEHAKDSLHDIRSISKSVVSACIGIAIQQGKIKSVDQRVFEFFPEYEKLDTGLIAGLTIKHLLTMTSGLKWNEDVPYDNAENSEIKMAFSKNQVEFVLSQPMDYPPGKSWKYNGGTTQLLAAIIERTTGKKIDEFAGEYLFKPLGITKFQWTKYPNTNYPAAASGLRLTSRDLMKFGLLYSQKGKWQNKQILSVQWVEDSFKPYTDLPFDGGKYGYQFWIWPTDFQGKTVNMVTAVGNGDQRIFFNSALDVVIVVTAGNYNTWNVQKNALALVREFINPALIKK
>NC_017770.1|WP_014678817.1|564993_565422_+|hypothetical-protein
MWTCPLCSQKFLHQNQTHSCNDRTIESFLEGKSIHTIGLYNTFINEYASIGDFVLHPAKSKIGLAAKIRFCSIIRLGKDFIDVVFHLNKLYNDTLCFHKAGQIPGSNTFNHHCRIYRVEDINEELKMYMKIALNLGEKKMQE
>NC_017770.1|WP_014678818.1|565438_566065_+|hypothetical-protein
MTILTQLASALNRNDEVPNQELALRIVKNDDVEAIKELVDNLKNKSKDIQKDCIKVLYEVGEKKPALIAGYVNVFFELLKNKNNRLQWGGMTALSSITLHDPAAIVEQLVKIIDAADNGSVITKDQAVAILIKLGSMDKYAEDAFSLLVEQLKSCPTNQLPMYAENAKPIVNEQNKEFFINTLSSRLNEIEKESKRKRVEKVIKQVSK
>NC_017770.1|WP_014678819.1|566067_566397_+|cupin-domain-containing-protein
MQITTTDALKKLDDSKELFLELFKHGTLSVEVYKPVGADFQTPHERDEVYVIISGSGDFYSDGKYYPFKPGDFLFVAAGVGHRFEKFTEDFSTWVIFYGPKGGEQNLVR
>NC_017770.1|WP_014678820.1|566472_566931_+|hypothetical-protein
MKKRLFFLGASAFLLVSCNSKPAKTTSAEQPPVEKKSNEFCYSYTQNKDNVFLNFKMSDDSLILGKLNYHFHEKDSNDGIVQGQMRGDTLFLDYIFTSEGVETVREVVFLKKGEDFVEGYGDAEEKNGRMVFKNTSKLDFNNSILLKHVDCK
>NC_017770.1|WP_014678821.1|566930_567260_+|multidrug-efflux-SMR-transporter
MKYVYLLLAILFEIIGTSALQASAQFTKWKPSLLVVLGYASAFFFLSLSLRSLQLGVAYAIWSGVGIVIIILAGIFLFKQIPDTPAIIGMALIVIGVVVINLFSKTTSH

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Crispr_ID: NC_017770_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_2

616061-616287

Orphan

Consensus_repeat	Method
GACTTTCATTGCCTTGATTTCCATAAGACGGACGACCCGAGTTATTGTCTG	PILER-CR

2 spacers

The CRISPR arrays of NC_017770_2

>merge|NC_017770|2|616061-616287|PILER-CR
ATTTCCGTAAGACGGACGGTTATTATTTTCTATTCTATCAGTATTACCAGGGTTGTTAGGACGACGACTTTCATTGCCTTGATTTCCATAAGACGGACGGCCCGAGTTATTGTCTGGACGATTTCCATTACCTGGGTTCTCATACGAAGGACGACCTGAATTGTTATTACCCGGACGATTTTCATTGCCTTGATTTCCATAAGACGGACGACCCGAGTTATTGTCTG

>NC_017770|2|1|616061-616287|PILER-CR
ATTTCCGTAAGACGGACGGTTATTATTTTCTATTCTATCAGTATTACCAGGG	TTGTTAGGACGACGACTTTCATTGCCTTGATTTCCATAAGACGGACG
GCCCGAGTTATTGTCTGGACGATTTCCATTACCTGGGTTCTCATACGAAGGA	CGACCTGAATTGTTATTACCCGGACGATTTTCATTGCCTTGATTTCCATAAGACGGACGA
CCCGAGTTATTGTCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014678873.1\|623158_623932_+\|zinc-dependent-peptidase	unknown	unknown	gnl\|CDD\|377621
NC_017770.1\|WP_042479177.1\|625509_625968_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273952
NC_017770.1\|WP_014678871.1\|620089_622696_-\|membrane-assembly-protein-AsmA	unknown	unknown	gnl\|CDD\|379224
NC_017770.1\|WP_014678872.1\|622832_623051_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678863.1\|610963_611608_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014678860.1\|606672_608058_-\|exosortase-N	unknown	unknown	gnl\|CDD\|275269
NC_017770.1\|WP_014678861.1\|608063_610577_-\|XrtN-system-VIT-domain-containing-protein	unknown	unknown	gnl\|CDD\|275270
NC_017770.1\|WP_014678862.1\|610626_610929_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|316153
NC_017770.1\|WP_014678866.1\|613486_614125_-\|CoA-pyrophosphatase	unknown	unknown	gnl\|CDD\|239518
NC_017770.1\|WP_052308534.1\|626595_628419_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_017770.1\|WP_014678869.1\|617544_618768_-\|glycoside-hydrolase-family-27-protein	unknown	unknown	gnl\|CDD\|269893
NC_017770.1\|WP_014678870.1\|618771_619941_-\|DUF5009-domain-containing-protein	unknown	unknown	gnl\|CDD\|226749
NC_017770.1\|WP_014678874.1\|623950_624313_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_017770.1\|WP_014678864.1\|611871_612537_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377943
NC_017770.1\|WP_014678877.1\|628509_629862_-\|cbb3-type-cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|238831
NC_017770.1\|WP_014678858.1\|603665_605120_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|131739
NC_017770.1\|WP_157604499.1\|624313_625393_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225375
NC_017770.1\|WP_014678859.1\|605189_606605_-\|cell-envelope-integrity-protein-CreD	unknown	unknown	gnl\|CDD\|377608
NC_017770.1\|WP_014678867.1\|614196_615609_-\|multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_017770.1\|WP_014678865.1\|612566_613490_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014678873.1\|623158_623932_+\|zinc-dependent-peptidase	gnl\|CDD\|377621	pfam06167, Peptidase_M90, Glucose-regulated metallo-peptidase M90. MtfA (earlier known as YeeI) is a transcription factor A that binds Mlc (make large colonies), itself a repressor of glucose and hence a protein important in regulation of the phosphoenolpyruvate:glucose-phosphotransferase (ptsG) system, the major glucose transporter in E.coli. Mlc is a repressor of ptsG, and MtfA is found to bind and inactivate Mlc with high affinity. The membrane-bound protein EIICBGlc encoded by the ptsG gene is the major glucose transporter in Escherichia coli. MtfA is found to be a glucose-regulated peptidase, whose activity is regulated by binding to Mlc available in the cytoplasm, which in turn has been released from EIICBGlc during times when no glucose is taken up. A physiologically relevant target for this peptidase is not yet known.	3.04978e-95
NC_017770.1\|WP_042479177.1\|625509_625968_-\|hypothetical-protein	gnl\|CDD\|273952	TIGR02071, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein 1B. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0.001385
NC_017770.1\|WP_014678871.1\|620089_622696_-\|membrane-assembly-protein-AsmA	gnl\|CDD\|379224	pfam13502, AsmA_2, AsmA-like C-terminal region. This family is similar to the C-terminal of the AsmA protein of E. coli.	1.89004e-18
NC_017770.1\|WP_014678860.1\|606672_608058_-\|exosortase-N	gnl\|CDD\|275269	TIGR04476, transmembrane_exosortase, exosortase N. Members of this family are exosortase N (xrtN), a bacterial exosortase variant whose single target, encoded always by an adjacent gene, belongs to the vault protein inter-alpha-trypsin family. This system occurs in a number of spirochete (Leptospira) and Bacteriodetes species.	4.96816e-169
NC_017770.1\|WP_014678861.1\|608063_610577_-\|XrtN-system-VIT-domain-containing-protein	gnl\|CDD\|275270	TIGR04477, sorted_by_XrtN, XrtN system VIT domain protein. Members of this subfamily average about 850 amino acids in length, ending with a variant form of PEP-CTERM sorting signal. Members have a VIT (vault protein inter-alpha-trypsin inhibitor heavy chain) domain (pfam08487). Other bacterial subfamilies of VIT domain proteins have members with either GlyGly-CTERM or LPXTG C-terminal sorting signals. Members of this subfamily occur only in context next to a protein sorting/processing enzyme, exosortase N (XrtN). These subsystems occur both among the Bacteriodetes and in the spirochete genus Leptospira.	0
NC_017770.1\|WP_014678862.1\|610626_610929_-\|transcriptional-regulator	gnl\|CDD\|316153	pfam13601, HTH_34, Winged helix DNA-binding domain.	2.13475e-31
NC_017770.1\|WP_014678866.1\|613486_614125_-\|CoA-pyrophosphatase	gnl\|CDD\|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	6.95444e-49
NC_017770.1\|WP_052308534.1\|626595_628419_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	6.94306e-42
NC_017770.1\|WP_014678869.1\|617544_618768_-\|glycoside-hydrolase-family-27-protein	gnl\|CDD\|269893	cd14792, GH27, glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	1.08123e-122
NC_017770.1\|WP_014678870.1\|618771_619941_-\|DUF5009-domain-containing-protein	gnl\|CDD\|226749	COG4299, COG4299, Uncharacterized protein conserved in bacteria [Function unknown].	1.26866e-13
NC_017770.1\|WP_014678874.1\|623950_624313_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	7.50572e-16
NC_017770.1\|WP_014678864.1\|611871_612537_+\|hypothetical-protein	gnl\|CDD\|377943	pfam07929, PRiA4_ORF3, Plasmid pRiA4b ORF-3-like protein. Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumorigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases, but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.	2.03497e-08
NC_017770.1\|WP_014678877.1\|628509_629862_-\|cbb3-type-cytochrome-c-oxidase-subunit-I	gnl\|CDD\|238831	cd01661, cbb3_Oxidase_I, Cytochrome cbb3 oxidase subunit I. Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. Found mainly in proteobacteria, cbb3 is believed to be a modern enzyme that has evolved independently to perform a specialized function in microaerobic energy metabolism. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme and a copper ion. It also contains a low-spin heme, believed to participate in the transfer of electrons to the binuclear center. The cbb3 operon contains four genes (ccoNOQP or fixNOQP), with ccoN coding for subunit I. Instead of a CuA-containing subunit II analogous to other cytochrome oxidases, cbb3 utilizes subunits ccoO and ccoP, which contain one and two hemes, respectively, to transfer electrons to the binuclear center. The fourth subunit (ccoQ) has been shown to protect the core complex from proteolytic degradation by serine proteases. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from cytochrome c on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. The polar residues that form the D- and K-pathways in subunit I of other cytochrome c and ubiquinol oxidases are absent in cbb3. The proton pathways remain undefined. A pathway for the transfer of pumped protons beyond the binuclear center also remains undefined. It is believed that electrons are passed from cytochrome c (the electron donor) to the low-spin heme via ccoP and ccoO, respectively, and directly from the low-spin heme to the binuclear center.	5.86217e-11
NC_017770.1\|WP_014678858.1\|603665_605120_+\|HD-domain-containing-protein	gnl\|CDD\|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	2.07742e-105
NC_017770.1\|WP_157604499.1\|624313_625393_-\|hypothetical-protein	gnl\|CDD\|225375	COG2819, COG2819, Predicted hydrolase of the alpha/beta superfamily [General function prediction only].	4.54465e-27
NC_017770.1\|WP_014678859.1\|605189_606605_-\|cell-envelope-integrity-protein-CreD	gnl\|CDD\|377608	pfam06123, CreD, Inner membrane protein CreD. This family consists of several bacterial CreD or Cet inner membrane proteins. Dominant mutations of the cet gene of Escherichia coli result in tolerance to colicin E2 and increased amounts of an inner membrane protein with an Mr of 42,000. The cet gene is shown to be in the same operon as the phoM gene, which is required in a phoR background for expression of the structural gene for alkaline phosphatase, phoA. Although the Cet protein is not required for phoA expression, it has been suggested that the Cet protein has an enhancing effect on the transcription of phoA.	0
NC_017770.1\|WP_014678867.1\|614196_615609_-\|multidrug-efflux-MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.20367e-96
NC_017770.1\|WP_014678865.1\|612566_613490_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	6.59223e-134

>NC_017770.1|WP_014678867.1|614196_615609_-|multidrug-efflux-MFS-transporter
MKNKYVVLSTLMIGTFMGSLDSSIVNVSLPIIKEDFNCRMDQIQWVVTGYMLSFSLFMPLTSWLKDRIGFFNLYVGGLVVFTIASLFCGIAQNLETLIIGRIIQAIGGGSLNPTAMAIMSTVFPKEERGKAIGWWGLGSVFGPTIGPTLGGFLTREFGWHSIFLINLPISVIAIGMCFYSLGFLKQVPKKYEKFDFKGFVSLTIFLSLIQFVLVRVESVGLLSYETVILLIVLIASLAYFIHTELRTTAPLLNIRLFRNKKFTSCILVTVVRSAALFGGLFLLPFLLQGLLHFNELESGLIMFPGALFMGILMPISGTMADKFGSRKLTIAGLIIVAFSMYLFSELGAQSNLTWVLVAVCLRGVGLGLLISPLSSATINSVKFEEVTMASSINSLLLQVGGSLGIAILTFIHQNVYNNKIDLDFSGAEAEQFALHRGFTISCILVTLALIPASRIPSKNLVTAKKEIVEI
>NC_017770.1|WP_014678866.1|613486_614125_-|CoA-pyrophosphatase
MHPKNLIDLLEKRLQEPLPGKEAHLQMIPALRLPDYEKGYDLVNARKSSVLLLLCTGQNTLFIPFIQRPVYEGVHGGQISFPGGKAEPEDLSPEDTALREAFEEIGIEREKVQVIGNLSPVYIPPSRFLVNVIIGYYSTDPIFVKSDIEVEEIFNVSVDSLLDDLYVTSVPVTNSQGLHFDAPCFKIDGKIIWGATAMMLSEFKWILKELSF
>NC_017770.1|WP_014678865.1|612566_613490_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MDYRLIRVTKEHRKKLIVIVGPTAVGKTRTAIELAKHFHTEIISADSRQFFKEISIGTAKPDMDELAEAKHHFINSHSIFDEINAGRFEVEALAVIAKLHQQYNQLIMVGGSGLYINAVCDGLDDLPKADETLRQQIVDQYEKEGIVYLQSEVERLDPQYFRQVDQSNPQRLMRALEVCLMTGQPFSSFRNNSSKERPFEVIKIGLNLPREELYARINHRVDLMVEVGLVEEARAMYPNKETYALQTVGYTELFDYFEGMHSLERAIELIKQNTRRFAKRQITWFNRDKNTTWFKPDEVEKIITFLG
>NC_017770.1|WP_014678864.1|611871_612537_+|hypothetical-protein
MAIYRFRVAFEDYDAVREIDIKSNQTFEDFHYAIHKAINYDANQASSFYVSNDQWIKGEELAFMPNERKVERGIKLMKDFKLSKFIDDPHQKFYYISNFDRPFDFHVELSKILLDPEAGVEYPVCVKSTGEPPKQFKAAAVVAATNKEPLESLDDEFDIEEPEELDEFGIDVEDFSSGGTATKTSDEEDEQSEVEDGEAEDEFGELGFGSGDDEYGDRDDY
>NC_017770.1|WP_014678863.1|610963_611608_-|hypothetical-protein
MDTNINKHLESLTEIRSLMERSSKFISLNGLSGIFAGVYALLGAAAAFWANQHYNKSFVPMNEYAPVFTLQNKFMLFCLIDALLVLFLSIGTAFILSKRKAGKIQHSLLDKSAQRLIINLCIPLFAGGMFSLALLLQSNYKLIAPSMLIFYGLSLINASKYTFGDIRYLGMVELVLGLINLFIIGYGFWFWCFGFGIMHIIYGSVMYRKYDSGN
>NC_017770.1|WP_014678862.1|610626_610929_-|transcriptional-regulator
MVVNLFQNFNKAFESKVRLGIMSILMVNDNVDFSTLKDLLQVTDGNLASHSKALEELNYIKISKQFIGKKPNTTYEATEIGKKAFADHLNSLELLLKSNK
>NC_017770.1|WP_014678861.1|608063_610577_-|XrtN-system-VIT-domain-containing-protein
MKLKHLTTMNRIGLLLIALSFLLFALRNPAHSANNFTFFWLHYLPAISFLFFSLIIREGKSFIQNLVSPNVIYSFLLFNISAFALNKEITVFDDSVNWLCLLLMVSSISLLLFATFEFESGFLVSLLCFFLGIATFLYAYFALLLASTYPIAILGAIVLGLSLHLLVPLLLLCVTIASFSTLQRKHTGLWPSYSIGLLIPLITAIVWVFVWQNRIEKIKTTTSLSLLNSESSLPNWVTVSQQLAPDLLTVKILKSGLLYRTFQDNIGFFEMPSGLTNEPKKHDPLIVLSSLGTPSEMLDRSSSINMLKVLSRNRHQTQEQLWSGDHLSVSRINSNVKIYPELQLAYTEKTISIHNNDQRGWNQNQEALFTFHLPEGSVITSLSLWVNGKEEKGLITTRSNAEKAYETIVGVEVRDPSVVKWQEGNTVTVRVFPCTNEEDRIVKIGITSPLPVADNIVSYENIWFEGPENSNAKEIVKVQFMRTPEDLKLPSGFNQEVTNTYLSNRDYQPDWMLSFKKQPLLPHSFSFNGYSYHFAPLKPEIQHFDPKSIYLDVNSSWSQQDFTAALKIFWNKDVYIYDNKFVKVTTQNRNALFEKLSSLTFSLFPIHQVTDLTSALLVTSSTLYSPTLDELKDSEFYNKLKTYCSNNPTPLKVIQIGDNESIYLKSLKELRVIQSIKQDWETLSTLINKEQFIAYPENENSVVISSAGLRIERTTDTSLTNNAPDHLLRLFAYNHLLFKIGNKGMATNSVATNLISEAGITNIVSPVSSLVVLERQSDYDQFNIKKYDNSLGNAAMNSSGAVPEPHEWMLIILIAGVFIYIFYPKLKGFLFLNIHKQ
>NC_017770.1|WP_014678860.1|606672_608058_-|exosortase-N
MIATNKMTIPDEMYKRLFFYSRIVLLIVASFPVLKSYFNTGPLFIGGILIMLYSLQPTEVASKRNWWLLPLTVCFYLSTQGVKTFYFISCVLALGWLIENYYGKINLLPFVALTVVSPIGDYIFNTLTFPFRLQLTQLVTICLNTVGYPIQAGGNLITVKGATFNIDEACSGLKMLETSMLLVILILAHVCKKHHYKLSFLQLLKWIALTLLLGLVANFFRIIFLVLFHIGPEHPFHYTAGIICLLCYCVLPLILLINKYCKGKQVNPVTPFASHHSTSFHVFSLILVCIVAFAGYFVRTKTYLVNPTVSVSGFKSENLTHGIVKLSNDQSLIYLKPLRNFYSTDHNPSICWKGSGYKMDFFTVKTIDDKKIYFGELTNKKDKLYTAWWYQSNVHFTIDQLEWRKRCLINDESFWLVNISAASPMELNNQIKQFIENKTNTSFMISQENKKTPSTHLNNLN
>NC_017770.1|WP_014678859.1|605189_606605_-|cell-envelope-integrity-protein-CreD
METHLSDFKQPNFWERNAIVLKLITIGILSLLLLIPSAMIQNLVIERSETRDNAVKDIYSKWGEQQTISGPILNVPYRVFIKNKEGKVEESIDYLHFLPEQLKINGTLNPSVKYRGIYEAILYNGKLACTGSFIAPDLNGLKVNPESVMWNDAFFTIGVTDLRGIKEVIKFEVNGKQLIVNPGISIGGVFDSGLSIPVQSVDASFYQRPITFNFNLDINGSSRLNFWPLGKETIVNLSSPWTTPSFSGAFLPEPREVNEKGFKATWKVLELNRNFPQKWTGDQYSFQSANENQLAYDGNKAEVATSAQKSSFEFGVDLLMPVDFYQKVYRSAKYALMFIALTFTAFFFIELVNKKRIHPIQYILVGISLVIFYTLLLSITEHMFFGWAYLIASGATIILITLFTASVLQSKGLAVLMGSLLSALYLFLFILLQMEDYALLIGSVGLFVILGIVMYVSRKVDWYDFRRKELK
>NC_017770.1|WP_014678858.1|603665_605120_+|HD-domain-containing-protein
MRKHLNHPIFKTISEQAAKANVEAYVIGGFVRDIFLKRPSKDVDILVIGNGVEFAKSVAKEVGLEKRLAVFKNFGTAMLKLEDLEVEFVGARKESYRAHSRKPIVEEGTLQDDQNRRDFTINAMAIRLNDGSTFGELVDPFNGLIDLEYKTIRTPLDPDITYSDDPLRMMRAIRFATQLHFTIEEKSLKAITKNKERITIVSAERISDELNKIILSKKPSIGFNLLFDTGLLELVFPQMVALYGVETINGRSHKDNFYHTLEVLDNICKLTDDLWLRWAAILHDIAKPATKRFEPNHGWTFHGHEDKGARMVSKIFRQLKLPLNEKMKFVEKMVLLHLRPIVLAQEIVTDSAVRRLLFDAGEDIDALMKLCHADVTTKNEYKIKKYKKNFELVQQKLKDVEERDQIRNWQPPVSGNDIMVMFQLPAGKEVGILKNLVREAILEGDIKNDREEALNFIVQKGVEMGFIVYDRAPVPEEEKDKKEV
>NC_017770.1|WP_014678869.1|617544_618768_-|glycoside-hydrolase-family-27-protein
MRSLLLLLLSVLLLNKQTCAQNNPKVLRPQTPIMGWSSWNNFRININEEIIKSQADYMVSTGMKDAGYSYVNIDDGFFGGRDGNGQLLVHPVRFPNGMQSIANYIHSKGLKAGIYSDAGINTCGSYWDKDTISTGSGLFGHDQQDLELMLNKWGYDFIKVDWCGGEWMELDEQTRYTAISTIIRAINPKVVYNICRWKFPGAWATHIADSWRISGDINNQYESILKIIDLNADLWKYASPGHVNDMDMLQVGRGMSYEEDKSHFSMWCMMNSPLLAGNDLRKMSKQTIEILTNKEVIALNQDPLVYQARRLVDNGDLELWAKPLYGTMSGMVAIALLNRSSKNDTIVLDLNAVGIDPDKGYIMRDLWSKKDYPFTRDQKQKFEVLPHGVIVLKIKGSMKPFNVFQYK
>NC_017770.1|WP_014678870.1|618771_619941_-|DUF5009-domain-containing-protein
MTKTINRLGSIDVIRALTMFLMIFVNDLWSLVNVPKWLEHVDVQTDGMGLSDVIFPAFLFIVGLSIPFSVENRIKKGDSTIQLLKHIFIRSFALLVIGFFHVNLESYNPGALLPKPIWQILITLAFFLIWLDYPRDMIKSRKFTLQGIGVAMLILLAAIYKGGDATHPVWMKHYWWGILGLIGWAYLLCSTIYVLSKGNLVALITSFIALIALNSAFHAQLMPPHLHLWVVGDGSTATITVAGILTALIYNKHSNHNLYLWLLLAGFAIVLFAFGFGTRPIWGISKLRGTPSWTTICSGIIIVVFMLLIWLVDIRKKESWFKILKPAGTATLTAYLLPYFHYAIYTIIGWKLPEVLRDGTIGIIKSLLYSLIIILITGWLEKRRIKLKL
>NC_017770.1|WP_014678871.1|620089_622696_-|membrane-assembly-protein-AsmA
MLKKVFITIAILIVVLLGAAVCVPLLFKDKIVAKVKSSINENVNAKVDFKDFDLTILSSFPNLGLRLNNLTVIGIDSFATDTLANIEQLQVNVNLMSVIKGETYEIRSVELDKPSIYAKVLKSGKANWDIAKPDSSATPSAEPTTFKAALKKYSINNGKVVYDDASLGFFMALENLNHSGKGDFTQDNFTLDTESDIEKLTVKYGGIPYLNKVNLSAKLPIDIDMKQMKFTLKENEIKLNELLLSFVGSLSMPNETDMAIDFKFDAKKSELKNFLSLIPAIYASNFKDLEASGKFAMDGSAKGIYNEKSLPAFNVNLLVENGKIKYPSLPSAINNIQVKTTISNPDGVIDHTQVNIPSFHLEFGAVPLDGRLLVKTPISDPYVDMALKGKVDLKQMTTIFPLKDMKLSGVLDADVQANGHKSSIDKGRYEEFKAAGQMVVSAFNYSGANVPKPVSIPSAKLTFNPKNISLTNFSAKVGESDFAANGSINNYLAYFFQKGQALQGTFDVSSTLVNVNELMGPATVETKNDTAKLSVIEVPANIDFTLTAKVGRVLYDNMDIQNARGALFVKNQTITFKDMSMDMLDGKVKMNGYYATTNPKKPKVDINFGIDNMNIQKAFSTFNTVKLLAPIAKYTAGTFSTDLKFNSDLNQNMMPVYSSINAEGLTNIIQAIVQGFEPMNKLSMALNTDKLKKLEVNNLLAKFRIEEGRLKVSPFDVKKGDFLMNVQGSNGLDQSMDYKLALKVPRSLLGSQANATVNSLVASLNSKAGTNVSVGETINVNALLGGSITKPTVKLQLANDKSAGQSVLAQAADEKKAELETKAKEEVTKLKEQATEQVKQKVDTVKKQATEKVKSEVKNKLKGLFGSK
>NC_017770.1|WP_014678872.1|622832_623051_-|hypothetical-protein
MRTLGLTLLLIGITILAFSGFSMIAKEKDFKVGRVEMNDPDHREISWIPILGGIIFIAGSVISVVYRNQQKV
>NC_017770.1|WP_014678873.1|623158_623932_+|zinc-dependent-peptidase
MEKIIGLLGIILLICLVRNYLGLNKKTTINPDNVNLRTILEDNVLFYSRLSPDQKRLFEEKINQFLAEIHIEGVGMEITDMDKVLVAASAVIPIFHFDHWKYKNLTNVLIYPDTFNEQFQYDNAQRNIAGMVGTGYMNGQMILSRRALYEGFKNHQDKSNTGIHEFVHLLDKSDGETDGIPESLLDHQYTIPWLTLMRDEIREIRKGSSDINPYGATNDAEFFAVASEYFFEQPQKFKEHHPELYKLMSDIFQVDAV
>NC_017770.1|WP_014678874.1|623950_624313_-|nuclear-transport-factor-2-family-protein
MTTNSLETIAGKWFDAFNEHDLEQLLSLYDDEAVHFSPKLKIRHPETNGLVQGKDALRAWWKDAFDRLPTLQYTPTSLTANNERVFMEYVRRVANEPDLLVAEVLEISDDKIVASRVYHG
>NC_017770.1|WP_157604499.1|624313_625393_-|hypothetical-protein
MNLQKLLSNCVIYLLTHSLAFAQSPDTSITPFCISYIETRMIHSAAVADDFKLYVRLPDNYSSSTNKYPVLYMTDGDWNMTVAMNCFSMLRQDYFITEPIIVGIGYGKGQNKRTRDLNPYTGGPKFLEFIEKEVMPWISGRYRTTNEKAIYGYSLGGMFTTYVLFNRPELFNMVFIGAPGNYAKTLLSESEKYFTTHNDLNAKVYAGVGEYERDAVKNLSLFQQYIESKECKNLIIETGVVPKANHGSGLAQVMQEAIAFGYCKKPKAIDLSPTAYKPYLGVYTTPTDSTLKMEIFEKDRKLYLKTTFNETPFELFASSKKDYFIEEMQKTFFSFEKDEQGKPYIIFINAENKQLKFFK
>NC_017770.1|WP_042479177.1|625509_625968_-|hypothetical-protein
MITEFDIQRRNKRVVDFFTRSGFQVKLLGDPNCPAIIYNDLFCLSCYVKNFDLIFTNRPKAGDEIFRVKLEAESKLERTELMDILDQAEHRRVYKVKISAADLFLSGYNFLDKARPETRYPVFAKYGAKLYFDEEYATQICHDYNEYNLVVV
>NC_017770.1|WP_052308534.1|626595_628419_+|TonB-dependent-receptor
MLKEVTVNSQRKKIYSAPGRVISVITANEIKNMPVHTVQDLLESVSSVDIRTRGENGVQADVSIRGGSFDQVLILLNGINVTDPQTGHHNLNLPVNLDDIDRIEILQGPGTRILGPNAFTGAVNIVTGEKKTKKLQASLAGGENGYLLGSVSAFYHKKELSIGSSANYSRSDGYIHNTDFNLGNYFLQMQYENAKAGKVNFQGGFQNKSFGANSFYSPAFKEQYEHTRTIFSSLQWNKNYEKLIVDASFYWRRNYDRYELIKNSSFGRNFHRTDVLGGQAKLSYFSQIGKTTVGVDYSNQQIVSTVLGVTLNNPSEVDFGSDISPIPQYVKGDNRNVLNTFIDHTIIVGALSLSGGLLNSWNEDYGSHWQGGADASYRITSDWQAFAGINQSMRLPTFTDLYYRGPDYAANNNLVPETALSYEAGVKYDRSKFGGSLSVYQRNGKDIIDWIKPPDSVKWQSSNISKVNTTGLELSVNYKPATSFIKRAQFELTWQKTDKDTKNYTSMYDLSFLRFKSEFILDHAIVKNLIASWRISYQQRAGNYKDFNTKAVVDYNPFTLLDLRLMYTLSNYAVFVESSNLFNTTYYDFGNLQQPGRWMKAGVKFRL
>NC_017770.1|WP_014678877.1|628509_629862_-|cbb3-type-cytochrome-c-oxidase-subunit-I
MFALQRFTIRFSLVLLLVTLIAGLLAACAYLFPNLFNHFLPFQLLRPVHTSAALFWIIGAAACCVSYLQYESNPSLNEKKGWNKAFMYLWVFTIIAVFIHYGLNQFGGREYWEFPPYLNLPLLAAWIFLIYSLFTPLNKSTPAYEWMWMTGLLFFLFTFLEQNAWQIPWFRESFRREITVQWKANGSMVGAWNQMIYGLSFFMMYKISGDRKMLHSRQTYFFYFLGLFNLMFNWGHHIYNLPNTNWMRHVAYAVSMTEWLFLLKIIRDFRKTLDTAKKLRHLVSYRFLTAAEFWVAANLILALLMSIPAFNRYSHGTHITVAHAMGTTIGINTFILLGAISYILRADLQQLKYKRIINITHKANQYFLGIFWVALIIAGWVKGYLTIEQPKMHYTQLMESVTPYIELFTFAGVGLMIGLGVIAIILLLMPFPQKTIEPTHELITAEDLQN

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Crispr_ID: NC_017770_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_3

1051083-1051155

Orphan

Consensus_repeat	Method
CTTTGCGCCATCGCGCCTTTGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_3

>merge|NC_017770|3|1051083-1051155|CRISPRCasFinder
CTTTGCGCCATCGCGCCTTTGCGATTTATTAATCGTTTAGTATAAAAAAACTTTGCGCCATCGCGTCTTTGCG

>NC_017770|3|2|1051083-1051155|CRISPRCasFinder
CTTTGCGCCATCGCGCCTTTGCG	ATTTATTAATCGTTTAGTATAAAAAAA
CTTTGCGCCATCGCGTCTTTGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014679239.1\|1059063_1059828_+\|Rossmann-like-and-DUF2520-domain-containing-protein	unknown	unknown	gnl\|CDD\|378484
NC_017770.1\|WP_014679235.1\|1054005_1055442_+\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NC_017770.1\|WP_014679234.1\|1053674_1053899_+\|CcmD-family-protein	unknown	unknown	gnl\|CDD\|275184
NC_017770.1\|WP_081480022.1\|1042425_1042866_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NC_017770.1\|WP_042479290.1\|1052933_1053596_+\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|273492
NC_017770.1\|WP_014679227.1\|1046506_1046692_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|283241
NC_017770.1\|WP_014679230.1\|1048374_1050990_+\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NC_017770.1\|WP_014679222.1\|1043018_1043252_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014679232.1\|1052181_1052841_+\|heme-exporter-protein-CcmB	unknown	unknown	gnl\|CDD\|225260
NC_017770.1\|WP_042479287.1\|1045297_1046383_-\|DUF2891-domain-containing-protein	unknown	unknown	gnl\|CDD\|378592
NC_017770.1\|WP_014679231.1\|1051158_1052061_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235640
NC_017770.1\|WP_014679236.1\|1055475_1055676_+\|dodecin-domain-containing-protein	unknown	unknown	gnl\|CDD\|377810
NC_017770.1\|WP_014679229.1\|1047507_1048149_+\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NC_017770.1\|WP_014679225.1\|1044276_1045233_+\|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl\|CDD\|349913
NC_017770.1\|WP_014679224.1\|1043778_1044093_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014679238.1\|1056418_1058959_+\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|224061
NC_017770.1\|WP_014679223.1\|1043394_1043772_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NC_017770.1\|WP_014679228.1\|1046906_1047509_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|239645
NC_017770.1\|WP_014679237.1\|1055903_1056320_+\|cytochrome-c-maturation-protein-CcmE	unknown	unknown	gnl\|CDD\|376989
NC_017770.1\|WP_014679240.1\|1059919_1060252_+\|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|131062

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014679228.1\|1046906_1047509_-\|NUDIX-domain-containing-protein	gnl\|CDD\|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	2.93422e-31
NC_017770.1\|WP_014679235.1\|1054005_1055442_+\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	1.30266e-127
NC_017770.1\|WP_014679234.1\|1053674_1053899_+\|CcmD-family-protein	gnl\|CDD\|275184	TIGR04391, hypothetical_protein, CcmD family protein. Members of this protein family are small (typically less than 50 amino acids in length), with the first half highly hydrophobic like transmembrane alpha helices and containing a nearly invariant tyrosine residue. Members from the Desulfovibrionales appear in the position of ccmD of system I c-type cytochrome biogenesis operons (see pfam04995). This family and pfam04995 appear very similar in sequence properties, but the very low level of actual sequence identify makes it unclear that the similarity reflects homology per se.	0.00444468
NC_017770.1\|WP_081480022.1\|1042425_1042866_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.40786e-15
NC_017770.1\|WP_014679227.1\|1046506_1046692_-\|CsbD-family-protein	gnl\|CDD\|283241	pfam05532, CsbD, CsbD-like. CsbD is a bacterial general stress response protein. It's expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear.	2.96002e-09
NC_017770.1\|WP_014679230.1\|1048374_1050990_+\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NC_017770.1\|WP_014679239.1\|1059063_1059828_+\|Rossmann-like-and-DUF2520-domain-containing-protein	gnl\|CDD\|378484	pfam10728, DUF2520, Domain of unknown function (DUF2520). This presumed domain is found C-terminal to a Rossmann-like domain suggesting that these proteins are oxidoreductases.	3.73637e-41
NC_017770.1\|WP_014679232.1\|1052181_1052841_+\|heme-exporter-protein-CcmB	gnl\|CDD\|225260	COG2386, CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component [Posttranslational modification, protein turnover, chaperones].	1.69875e-08
NC_017770.1\|WP_042479287.1\|1045297_1046383_-\|DUF2891-domain-containing-protein	gnl\|CDD\|378592	pfam11199, DUF2891, Protein of unknown function (DUF2891). This is a bacterial family of uncharacterized proteins.	0
NC_017770.1\|WP_014679231.1\|1051158_1052061_-\|hypothetical-protein	gnl\|CDD\|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	0.00361461
NC_017770.1\|WP_014679229.1\|1047507_1048149_+\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	7.62776e-75
NC_017770.1\|WP_014679225.1\|1044276_1045233_+\|M20/M25/M40-family-metallo-hydrolase	gnl\|CDD\|349913	cd05663, M28_like_PA_PDZ_associated, M28 Zn-peptidase containing a protease-associated (PA) domain insert and associated with a PDZ domain. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. This subfamily is composed of uncharacterized proteins, many of which contain a protease-associated (PA) domain insert which may participate in substrate binding and/or promote conformational changes, influencing the stability and accessibility of the site to substrate. Proteins in this subfamily are also associated with the PDZ domain, a widespread protein module that has been recruited to serve multiple functions during the course of evolution.	2.78931e-73
NC_017770.1\|WP_014679236.1\|1055475_1055676_+\|dodecin-domain-containing-protein	gnl\|CDD\|377810	pfam07311, Dodecin, Dodecin. Dodecin is a flavin-binding protein,found in several bacteria and few archaea and represents a stand-alone version of the SHS2 domain. It most closely resembles the SHS2 domains of FtsA and Rpb7p, and represents a single domain small-molecule binding form.	3.54839e-22
NC_017770.1\|WP_014679238.1\|1056418_1058959_+\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|224061	COG1138, CcmF, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones].	6.34629e-79
NC_017770.1\|WP_014679223.1\|1043394_1043772_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	0.00259459
NC_017770.1\|WP_042479290.1\|1052933_1053596_+\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|273492	TIGR01191, Heme_exporter_protein_C, heme exporter protein CcmC. This model describes the cyt c biogenesis protein encoded by ccmC in bacteria. It must be noted an arabidopsis, a tritcum and a piscum plant proteins were recognizable in the clade. Quite likely they are of organellar origin. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes, ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in the heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other].	7.72298e-18
NC_017770.1\|WP_014679237.1\|1055903_1056320_+\|cytochrome-c-maturation-protein-CcmE	gnl\|CDD\|376989	pfam03100, CcmE, CcmE. CcmE is the product of one of a cluster of Ccm genes that are necessary for cytochrome c biosynthesis in eubacteria. Expression of these proteins is induced when the organisms are grown under anaerobic conditions with nitrate or nitrite as the final electron acceptor.	6.00242e-13
NC_017770.1\|WP_014679240.1\|1059919_1060252_+\|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein	gnl\|CDD\|131062	TIGR02007, 2Fe-2S_ferredoxin, ferredoxin, 2Fe-2S type, ISC system. This family consists of proteobacterial ferredoxins associated with and essential to the ISC system of 2Fe-2S cluster assembly. This family is closely related to (but excludes) eukaryotic (mitochondrial) adrenodoxins, which are ferredoxins involved in electron transfer to P450 cytochromes. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.77942e-24

>NC_017770.1|WP_014679230.1|1048374_1050990_+|ATP-dependent-chaperone-ClpB
MNFNNFTIKAQEAVNKASEIAMGFQQQSIEPAHLLKGILSVDENIATYLLKKLNVNVQRLETGLDEQIQSFPKVTGSGIYLSNDATKALQKAQSYLKEFNDEFVSIEHILLGVLNGSDKTASLLKDLGVNEKDLKKAINQLRGGSRVTDQNAEATFNALNKYAKNLNEMAQQGKLDPVIGRDEEIRRVIQILSRRTKNNPILIGEPGVGKTAIAEGIAHRIVDGDVPENLKTKTIFSLDMGALIAGAKYKGEFEERLKAVVKEVQGSDGEIIMFIDEIHTLVGAGGGEGAMDAANILKPALARGELRAVGATTLNEYQKYFEKDKALERRFQKVMVEEPTREDAISILRGIKDRYESHHKVRIKDEAIIASVELSQRYISDRFLPDKAIDLMDEAAAKLRLEMDSKPEALDELDRKIMQLEIEREAIKRENDEKKLAQLNEEIANLSEQRNEIKAKWQGEKDVVEELQSKKKDLESFKLAIEQAKRNGDFAYASELQYGKLPETEQQIEELGKKLDEMQHGQKMLKEEVTYEDIAGVVSRWTGVPVTKLVESEKQKLLHLEDELHKRVAGQDEAIEAVADAIRRSRAGLQDKNRPIGSFIFLGTTGVGKTELAKALAEILFNDEHNMVRIDMSEYQERHAVSRLIGAPPGYVGYDEGGQLTEAVRRHPYSVILLDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVDFKNAIIIMTSNIGSQLIQDSFQEMDDYNKEEVLARTKNEVFEILKKNVRPEFLNRIDEVVMFSPLSRDHIGEIVRIQFASVQRTLLEIGIEMEATDEALDWLAQLGYDPQFGARPLKRVMQKRILNELSKQILSGKVQKDSRIQLDMFDKQFVFYNVKEGEKEVS
>NC_017770.1|WP_014679229.1|1047507_1048149_+|orotate-phosphoribosyltransferase
MSFKNESAVKIAEFLMQIKAIKLQPENPFTWTSGWKSPIYCDNRVSLSHPSVRTYIRQQLTNLIKEEFGSVGAIAGVATAGIPQGVLVAQDLGLPFAYVRSEAKKHGMGNQIEGELMPGERVVVVEDLISTGKSSLAAVEALRAAGHDVAGLVSIFNYGFNQTEEAFKEAKCVFHSLSDYNVLVETALKNGFILEAQLPTLNAWREDPAKWGK
>NC_017770.1|WP_014679228.1|1046906_1047509_-|NUDIX-domain-containing-protein
MAQRYRIYIKDTPLFICPPAESSNSKTLTIVNEHNIDEIVRKILHNNASEPLLLESNSPDNTLHKLCKKFHFIEAAGGLVKNSLEEYLFIHRLGKWDLPKGKLEKNESIMECAIREVEEECGITINRIIEELPSTYHMYELKGKIVLKRTYWFSMEYTGEQQLTPQTEEDITEVEWLPKEQFNKVIDNTYPAIKELISTI
>NC_017770.1|WP_014679227.1|1046506_1046692_-|CsbD-family-protein
MDTLELKGKWNEIKGKIKQSYADLTDDDLKYEEGKQDELLGRLQQKLGKSRDELISWIKSL
>NC_017770.1|WP_042479287.1|1045297_1046383_-|DUF2891-domain-containing-protein
MKKNLLSLIFLFFAQLLFAQTKTQDLFNQDIAGKLAAMPLHCIPNEWPNKTSHTSDTASDHVLLPHELHPVFYGCLDWHSSVHGHWMLVKLLKTYPNLPDRDKIIALLNNNFQLDKIKSEADYFSKYKTSKIYERTYGWAWLLKLDQELYTWDDPIGKQWYANLQPLTATIKELWTTYLPKQTYPNRTGVHPNTAFGLVFALDWAQTLKQTEFAELIKKRSKDYYFANKNTPANLEPDGTDFLSPSLEIADLMSRVLSKEEFVKWFNSFYSKEGVTNITQLPVVSDRTDYQIVHLDGLSLSRAWCMKGIAKMLPTNHPYKKLFVSTADSFLKNTLPHVTSGNYGGDHWLASFAVYAIFDVN
>NC_017770.1|WP_014679225.1|1044276_1045233_+|M20/M25/M40-family-metallo-hydrolase
MRVSFFLLLFFLPFKQLLAQSEITEAEIKQHIEFLSSDENRGRFPGTKETKKVVDYLIENFRKAGISKLNGSFRQPFVAKLRVMPGVKDTPYVKTWNVVGVIEGSDPVLKKEYIVLGAHYDHLGMGGPSSKKKDTVAIHHGADDNASGTAALLEIGEKLSANRSLLKRSIILISFGAEEQGLLGSKYFTEHPTVPLNSIKLMINMDMVGRLNESGHIYMGGAGTFDGGVELMKGLGKEFNLNPIVHAGDVGGSDHISFYKKQISVLGLHTGGHPQYHTPEDIASLINIKGEKQVCEYIYQAIVHMAQQTTPINFIYQN
>NC_017770.1|WP_014679224.1|1043778_1044093_+|hypothetical-protein
MQARHLGTLIKNTLEENGMMLQEFAERMYLTVDETHALLDQKDISVFQLQRASEILKTDLFDYVSTNRTIMNFSIAIPGDKARQAIDLHNEIEKLVERYGFKLD
>NC_017770.1|WP_014679223.1|1043394_1043772_+|helix-turn-helix-domain-containing-protein
MIETLGQKVLFELEKRGVSQAFAAKQLGLTRQYVNKLGTKKTFSLQFLERLRDTLGIDFVDQADHKEAKIEAQPRNEVYNPEESGDIFTITMNLELKAKQANYARIPELITIIKSEALRLGITIK
>NC_017770.1|WP_014679222.1|1043018_1043252_-|hypothetical-protein
MQGYKSGTLSKKSLDKLKQKVVGHYKQVAVKAECTPEYVSMVLSGVRKSEAVINAALAVSLELKESNDKLNQLIKNL
>NC_017770.1|WP_081480022.1|1042425_1042866_-|helix-turn-helix-transcriptional-regulator
MYSHPEAIEALIDHEMVTDDEMLWQYIRCRFGGFDGKPDITYNNSTPTRSYQIEHTEYWECGFRGNCPMEGRLCASIKVKNGYLTPREIEILKLFGDGLLDKEVADKLNISIGTVPSFKKRIQEKTGMVRKTDFTRIAFELNLIQR
>NC_017770.1|WP_014679231.1|1051158_1052061_-|hypothetical-protein
MKKLLFFLALLMPFTVLAQTITSKSMAKAPVKKTAKPIDTAQKKKVAVKKVIYDSIVTLTENTIQDSVKKKAVKKTVKPTDSLVKKAGAKKTVKPTDSLMKKAGVKKTVKPADSLAKKAAVKKTGKTADSATTVKLPKGWFEISGSDSTDIRESLLKKNAEEWFTDWFSITNERNQGFKASVADSINRDRGYYLGHGTYAMKDTLSQNRISSIKMDYKTEVKVKGKSYQYRFYDFKIKSTLLQNGKVISDEMVDMEAEKEQTKDQYHTWRLKKLQNEMQNILDNFQSMMQQEPQRLNAFE
>NC_017770.1|WP_014679232.1|1052181_1052841_+|heme-exporter-protein-CcmB
MTLVSQVQSLIKKEIVLEWRSKYAINGIFLYIAATVFICYQSFKKVDPITWNALFWIIMLFAAINAVAKSFMNESKERQLYYYTLISPQAIIISKIIYNFLLMLLLSVIALFFYNIVFSNPIGDLFLYLVCVVIGSLSFATAFTMISAIASKAGNNATLMAILSFPVVIPVLMAIIKLSKNAMDGLDRSVSTDEIILLLGINVIITATSLLLFPYLWRE
>NC_017770.1|WP_042479290.1|1052933_1053596_+|cytochrome-c-biogenesis-protein-CcsA
MMKNWWKILAVILTFYSILAGLLFEVPHLAILHETIRNLYFHVPMWFAMIMLFLSSVIYSVKYLRTGHENDDLIAVESANVGIVFGLLGLITGSLWAKFTWGAWWNSDPKQNSALIALLIYLAYLVLRGSLDEEQKRARIGAIYNIFAFPVMIVLIFVLPRMTDSLHPGNGGNPGFNSYDLDSRMRGIFYPACLGWILISFWIMQIRFRMRKLENHFLSK
>NC_017770.1|WP_014679234.1|1053674_1053899_+|CcmD-family-protein
MKKYILSILLTLMSLATFAQNANGIEMADTLRSSGKIYIVVGVIAIIFIGIIVYLVSIDKKLSKLEKEHQHLKK
>NC_017770.1|WP_014679235.1|1054005_1055442_+|Glu/Leu/Phe/Val-dehydrogenase
MAKKPSKAAAHEISFWDDVCDYFNHAATFTDHPKDILEMIRECNSIYSFKFPIRANGGFELISAWRVEHSHHKLPTKGGIRYSEFVHEDEVKALAALMTYKCAIVNVPYGGAKGGVKVNPKKYSERELENITRRYTSELIKKNFIGPGTDVPAPDYGTGEREMSWIVDTYQAYNPGQIDSNACVTGKPLAQHGIAGRREATGRGVFFAARECVNVPEDMKKVKLSVGLEGKRVIVQGLGNVGYYSAKFIQEAGGIIVGLCEYEGAIYDSKGLDVDDVVRHRKETGSILNYKKAKNFKNSSEGLEQECDIFVPAALENQIHDGNIAAIKAKIIVEGANGPTTPDAATAFIKRGGIIVPDMYANAGGVTVSYFEWLKNLSHVAFGRMNKRFEENAARNMVDMIERMTGQSITADQRTVIVKGASELELVNSGLEETMVRAYHEIRDIQLANKKITDLRMAAFVCAIDKVAISYKNLGIFP
>NC_017770.1|WP_014679236.1|1055475_1055676_+|dodecin-domain-containing-protein
MGIVKVIEVIATSDKSIDDAVRNAVTEVSKTVRNIDSVFVKDIKAHVKDGQVTTFGVICQLSFRVD
>NC_017770.1|WP_014679237.1|1055903_1056320_+|cytochrome-c-maturation-protein-CcmE
MKKTHIVGIAIIAVAIAIIVSTYGNSSTYASFAEAKETSKELHVVSHLVKEKPQYYDPIKDANYFSFYAKDNNGNECKVVFFGTKPQDFEKSEQIVLTGGMVGNEFHASKILMKCPSKYTDQEGEMKEFTSKKTTASL
>NC_017770.1|WP_014679238.1|1056418_1058959_+|cytochrome-c-biogenesis-protein-CcsA
MDIQYVGEHLLPGKLGQFFIVLAFGASLLSTIAYYFQTVKDKEDTSWRQIGRWSFRIQSVAVIVIIASLFYIIYNHYFEYNYAWSHSSKTLPVEYMISCFWEGQEGSFLLWAFWQLVIGNVLMRTAKSWEDSVMTVIGLSQVFILSMLLGVEIFGHRIGSSPFILLREAMANAPVFKDPEYLIKYISDGKGLNPLLQNYWMVIHPPTLFFGFASMVAPFAYAIAGLWTKRITEWVKPAIPWALIAVMVLGAGIIMGSFWAYEALNFGGFWAWDPVENASLIPWLTMISAVHVLIVYKNTGHSYFTGLFLTVISYILVLYASFLTRSGILGETSVHSFTDLGMSGQLVIYVLAFLVLSTVLIVINWKKMPFTEKEESIYSREFWMFIGALVMTLSCLQVIGFTSVPVINKLIGTDIAPPLEPVPFYNKWQMPFAMVVAILLGFSQFMKYKKTEAAKFWISTGVSLVMSLVITFIICYFTFFGGLKLIYGEGFTNENDFNWMFPVLIFAAVFGVLTNFTVLADAVKGKFKLTGSAVAHIGFGLMLIGAVVAASQNKVISVNTSGFDYGEQFDAKNKRENILLWKNEPMKINKYTVTYLGDSTEGVNTYYRVNYKVLDENNQVKESFDLFPLGQQNPSMGLVASPDTRHYLTHDIYTHVSSVPKKEVEGEEHAPHEGHNEDEEYNKPISYKVSIGDTIFFDEGKVIVRSVNRKAQLKDIPLSGNDVAIGISLDVVANDDNKVTPVEPVYLIKNNAAFSFPKKMDEFGLKFRLVKIIPEDHKFEIEMLKKPGKQKDYIIMKAIVFPYINLLWSGTIIMVIGFAFAISRRIKELRATSGAQAADKKVKQVA
>NC_017770.1|WP_014679239.1|1059063_1059828_+|Rossmann-like-and-DUF2520-domain-containing-protein
MKIVFLGSGNVATNMSIAMQNAGHAVMQIYNHRIESAKLLAEELKCSYTDQLTDISVQAEVYVISVKDDVIEELAKQLSISGKVVVHTAGSVPMEALSAATTNFGVLYPLQTFTKGRLLDFKTIPLFVEAADERTLAIIKELANTISSSVKEADFEQRKILHLSAVLACNFVNHLYDLSQDLLKVYQLDFDALRPLVLETALKVQKMNPHEGQTGPARRNDQLVIAKHLQLLSNNVPLKNIYTILTDSIVKSYQ
>NC_017770.1|WP_014679240.1|1059919_1060252_+|2Fe-2S-iron-sulfur-cluster-binding-domain-containing-protein
MNVYKVKFNFEEEGKEPVELTIAEGESVLDVALENDIELQHNCGGVCGCSTCHIYVLNGMDNIQDISDKEEDFIDRAVNPKITSRLGCQCVIIDGNIEIMVPDQSGFMGH

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Crispr_ID: NC_017770_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_4

1369963-1370103

Orphan

Consensus_repeat	Method
AAAGAGCGCGAAGCTAAAGAAGCAGCAGATAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_4

>merge|NC_017770|4|1369963-1370103|CRISPRCasFinder
AAAGAGCGTGAGGTAAAAGAGGCTGCAGATAAGAAAGAGCGCGAAGCTAAAGAAGCAGCAGATAAAAAAGAACGCGAAACAAGAGAAGCTGATAAAGTAGCTAAACAAAAAGAGCGCGAAGCTAAAGAAGCCGCAGATAAA

>NC_017770|4|3|1369963-1370103|CRISPRCasFinder
AAAGAGCGTGAGGTAAAAGAGGCTGCAGATAAG	AAAGAGCGCGAAGCTAAAGAAGCAGCAGATAAAAAAGAACGCGAAACAAGAGAAGCTGATAAAGTAGCTAAACAA
AAAGAGCGCGAAGCTAAAGAAGCCGCAGATAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014679492.1\|1383818_1385135_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NC_017770.1\|WP_014679489.1\|1378775_1380869_-\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|235537
NC_017770.1\|WP_014679479.1\|1363937_1364645_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|184722
NC_017770.1\|WP_157604676.1\|1359427_1359859_+\|NIPSNAP-family-protein	unknown	unknown	gnl\|CDD\|311781
NC_017770.1\|WP_042479379.1\|1377042_1377360_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014679483.1\|1370915_1372895_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NC_017770.1\|WP_014679491.1\|1383123_1383771_-\|LysE-family-transporter	unknown	unknown	gnl\|CDD\|280058
NC_017770.1\|WP_014679480.1\|1364732_1365974_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NC_017770.1\|WP_014679484.1\|1372987_1374802_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340824
NC_017770.1\|WP_014679472.1\|1356717_1357557_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014679475.1\|1359973_1360825_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014679485.1\|1375034_1376390_+\|pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|273464
NC_017770.1\|WP_014679473.1\|1357561_1358413_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014679477.1\|1361569_1362058_+\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NC_017770.1\|WP_014679476.1\|1360994_1361573_+\|GDP-mannose-pyrophosphatase-NudK	unknown	unknown	gnl\|CDD\|184971
NC_017770.1\|WP_169313280.1\|1366386_1368909_+\|gliding-motility-associated-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|372639
NC_017770.1\|WP_014679478.1\|1362307_1363654_+\|trigger-factor	unknown	unknown	gnl\|CDD\|272913
NC_017770.1\|WP_014679488.1\|1377444_1378641_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NC_017770.1\|WP_014679490.1\|1381042_1382227_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|367314
NC_017770.1\|WP_052308554.1\|1382736_1383093_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014679489.1\|1378775_1380869_-\|phosphate-acetyltransferase	gnl\|CDD\|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
NC_017770.1\|WP_014679479.1\|1363937_1364645_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|184722	PRK14514, PRK14514, ATP-dependent Clp endopeptidase proteolytic subunit ClpP.	1.33606e-118
NC_017770.1\|WP_157604676.1\|1359427_1359859_+\|NIPSNAP-family-protein	gnl\|CDD\|311781	pfam07978, NIPSNAP, NIPSNAP. Members of this family include many hypothetical proteins. It also includes members of the NIPSNAP family which have putative roles in vesicular transport. This domain is often found in duplicate.	3.54022e-08
NC_017770.1\|WP_014679483.1\|1370915_1372895_+\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	1.166e-38
NC_017770.1\|WP_014679491.1\|1383123_1383771_-\|LysE-family-transporter	gnl\|CDD\|280058	pfam01810, LysE, LysE type translocator. This family consists of various hypothetical proteins and an l-lysine exporter LysE from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators. LysE exports l-lysine from the cell into the surrounding medium and is predicted to span the membrane six times. The physiological function of the exporter is to excrete excess l-Lysine as a result of natural flux imbalances or peptide hydrolysis; and also after artificial deregulation of l-Lysine biosynthesis as used by the biotechnology. industry for the production of l-lysine.	3.01237e-08
NC_017770.1\|WP_014679480.1\|1364732_1365974_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NC_017770.1\|WP_014679484.1\|1372987_1374802_-\|glycosyltransferase	gnl\|CDD\|340824	cd03793, GT3_GSY2-like, glycogen synthase GSY2 and similar proteins. Glycogen synthase, which is most closely related to the GT3 family of glycosyltransferases, catalyzes the transfer of a glucose molecule from UDP-glucose to a terminal branch of a glycogen molecule, a rate-limit step of glycogen biosynthesis. GSY2, the member of this family in S. cerevisiae, has been shown to possess glycogen synthase activity.	0
NC_017770.1\|WP_014679490.1\|1381042_1382227_-\|aminopeptidase	gnl\|CDD\|367314	pfam03051, Peptidase_C1_2, Peptidase C1-like family. This family is closely related to the Peptidase_C1 family pfam00112, containing several prokaryotic and eukaryotic aminopeptidases and bleomycin hydrolases.	3.12931e-15
NC_017770.1\|WP_014679485.1\|1375034_1376390_+\|pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|273464	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family].	1.24415e-162
NC_017770.1\|WP_014679492.1\|1383818_1385135_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NC_017770.1\|WP_014679477.1\|1361569_1362058_+\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	1.08074e-06
NC_017770.1\|WP_014679476.1\|1360994_1361573_+\|GDP-mannose-pyrophosphatase-NudK	gnl\|CDD\|184971	PRK15009, PRK15009, GDP-mannose pyrophosphatase NudK; Provisional.	2.72714e-86
NC_017770.1\|WP_169313280.1\|1366386_1368909_+\|gliding-motility-associated-C-terminal-domain-containing-protein	gnl\|CDD\|372639	pfam13585, CHU_C, C-terminal domain of CHU protein family. The function of this C-terminal domain is not known; there are several conserved tryptophan and asparagine residues.	1.49678e-27
NC_017770.1\|WP_014679478.1\|1362307_1363654_+\|trigger-factor	gnl\|CDD\|272913	TIGR00115, tig, trigger factor. Trigger factor is a ribosome-associated molecular chaperone and is the first chaperone to interact with nascent polypeptide. Trigger factor can bind at the same time as the signal recognition particle (SRP), but is excluded by the SRP receptor (FtsY). The central domain of trigger factor has peptidyl-prolyl cis/trans isomerase activity. This protein is found in a single copy in virtually every bacterial genome. [Protein fate, Protein folding and stabilization].	1.42968e-49
NC_017770.1\|WP_014679488.1\|1377444_1378641_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NC_017770.1\|WP_052308554.1\|1382736_1383093_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	2.12945e-26

>NC_017770.1|WP_169313280.1|1366386_1368909_+|gliding-motility-associated-C-terminal-domain-containing-protein
MKIARSFTSRLAVFVSCLSLLLTVERTTAFPLVQTSALSIHQKLYFSFLYNSPYFVGISNNTISQPYIPGTCSATFFNPTIIDGTPAFPITGYRWEKSTTMGATWVSVGAVTEDYDPPGLTATTWYRRIAINGTEELASNIVKIVIAPVPLTKNSITADQDIIKGVVPAGLIGSQPAGGDGKSYEYLWEFSIDAQSWQSAPGVSNAKDYQPVALTVTTFFRRVVSMGVCNDLTSNTVTIKIVPVKISNNSIIQPLDNEKCGVDSFNPGVIDGTVASVTTGATFVYQWEQSIDGGSSYTDIAGASAKSYDPPTLTQTTFFRRKVISNGTSDTSKHVFIIINNVGVSNNTITSVPDVIAGTAPDLIVGSDPQPTGAIFDYNWEQSTDGNNWTTALGNSDKRDYQPPVITVATHYRRKIGSGVCPTSISEPIKINVIQPGGISNNKITAPPTTSYCGLATVDPDPITGTEARNAISYQWQKKTTGAWASITDATGQNYDPSGLTMKTDFRRIAIAGINKDTSNVVSFLITPVAIDNNTITSSPQVIPSGSIPAIIAGSQPTGGSGTYTYLWEKSEGGQNNWVPASGMNNQVNYQPPAQNAAVYYRRTITSGACSSTSDKYLISIITTADLTIKKEGGISDDVQEAVQFVITAINKGPQDAMNIVVRDTLSNDIEYISATTDVGLVDYDPIKKIIKWEIDRLNNQEEKTLKITAKPLVTHNIVNTAHISAPVNDSDLTNNKFTAIIREVVFGIDGTKIPNMITPNADGKNDFFVVPQLESFANNELTIMDRWGNRVYTVKGYKQDWGGEGLSEGTYFYVLKITVGSKVKLYKGFITLMRSRISG
>NC_017770.1|WP_014679480.1|1364732_1365974_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MSKNQKDVRCSFCGASKQDVMLMIAGIDGHICDRCLEQGYQILNEETAQNKAKKTQLELNLVKPLEIKKHLDQYVIGQDDAKRVLSVAVYNHYKRLNQKIEKDEVEIEKSNILMVGETGTGKTLLAKTIAKILHVPFCICDATVLTEAGYVGEDVESILTRLLQAADYDVAAAERGIVYIDEVDKIARKSDNPSITRDVSGEGVQQALLKILEGTVVNVPPQGGRKHPDQKMIAVNTSNILFICGGAFDGIEKKIGNRLQTQAIGYGTNKHAEKIDKNNMLQYITPKDLKSFGLIPELIGRVPVLTYLNPLDRDTLLSILVEPKNSLIKQYIKLFSYEGIRLEFDQDVLEYIVDKAMEFKLGARGLRSICEAIMIDHMFELPSQSDVKELSISLDYAKEKFEKSASMKNLKVA
>NC_017770.1|WP_014679479.1|1363937_1364645_+|ATP-dependent-Clp-protease-proteolytic-subunit
MKDRIDKNEFRKYAVKHHRINSLAVDGFISRVENRKLPTNITPYIIEERPMNVASMDVFSRLMMDRIIFLGDPIYDVTANIVQAQLLFLQSVDAKRDIQLYLNSPGGSVYAGLGIYDTMQFVEPDVATICTGMAASMGAVLLCAGAAGKRAGLAHSRVMIHQPMGGAEGQASDIEITAREIGKLKKELYEIIARHSSQTYEKVWECSDRDYWMIADEAKAFGMIDEVLTSNRDTK
>NC_017770.1|WP_014679478.1|1362307_1363654_+|trigger-factor
MNITQEKINDLGSVITINIQPADYKAKVEKAIKDQSKKARIPGFRPGMVPAAHIKKMYGKSILLDEINNLLSDSLNNYISDNKLEVLGQPLPKVDQDRDYKWDFEDTFEFSYEVGLAPDFKADFSSKDKFTKYKISADEETIKSRMESLQRAYGKMTNPEKSAEGDSIYGELVQLAEDGFVLEGGISHTTSVRIELVEDAKIKKSLIGLKKDDVVSFDIQKAYKNNATLIHNLLNISEEEAAEVKGNFQLTVKNVNRLEAAELNEEFFNKVFPDGSVTSADTFKEYVVKEIESQMQMNADRKLSNDIYEYAVDKIKFDLPSDFLKRWLKATNEKLTDEELEKDYAGFEKNLKWTLIENKVVQSNNIEIKPEEVIALAKERIAAQFAMYSPTPLSDVQLNEYTQNFISDRERATQMYNEVRSNRVFEFLKNTVETKEKAIDYKSFLELK
>NC_017770.1|WP_014679477.1|1361569_1362058_+|DinB-family-protein
MTVKNTRTGAVGALMDIYEAAISKLKTVIEDIPDDYLTVILDPSTTDESCKTIQAILTHVVSSGYGYATSIHNLKGHNAKRPDKSFHLTIAEYTEELNNVFAYTENVFKEISDDELEQFDDSLKIKAGWGQLYDIEQMTEHAIVHILRHTRQIARIKEQKLK
>NC_017770.1|WP_014679476.1|1360994_1361573_+|GDP-mannose-pyrophosphatase-NudK
MNNKVNILNTEILSDNWYILKKITYEYAQKDGKTQVQSREAYDRGNGATILLYNRPQKTVILTRQFRLPTFINGNHSGLLIEACAGLLDKDNPEDCIRRETEEETGYKISDVRKIFEAYMSPGSVTEILHFFIAEYSKEMKVTDGGGVEHEGENIEVLEITIDEAMKMIASGEIKDGKTIMLLQYIKLNNLL
>NC_017770.1|WP_014679475.1|1359973_1360825_-|hypothetical-protein
MKTLSIYSILLTMLIMACQKDTDESPLSSEKKKDHCNKCPTIYLPKTYSEAKYSFTYKDSTGNLATIVENTYMKVHFIYGNNNRIEKLQWMDDDGVLYDNYELTYTGNKLTKLTKNYSGGYTVDNYTIRWDGDKIKNLVIRRVEDSQITNRDSIIFSYNSDNSIAGYEFYDPNQKELTAGYSFSYKSSEYKYWAKDIKNKEIIFLALIDSSPKIVPASNDISSILKYEFTEYGQNFFESTYHDQQYNEANYPLTYGKTYRVSDEMEQWVEESQQCVSYIKVNK
>NC_017770.1|WP_157604676.1|1359427_1359859_+|NIPSNAP-family-protein
MKSGIKTILVVSILLTVLMAFHNKETSIESPIHQLRIYQVPKENRMVFHERFRDHAHRIMKKYGFNIVSIWESNFNNKVEFVYLLEWKDKKTMENAWKNFMADQEWKDIKKESSKIHGTFVENIEDRTLMLTDYSPQKKLLKE
>NC_017770.1|WP_014679473.1|1357561_1358413_+|hypothetical-protein
MKTHTLYLLILCFSFIGCQKDIGETDAELAAKKEKDCKCKKERYLPVMIVDSSLDYTIPVVDTFRIKYHDNKGNISCITSSRSKASIKFHYNSSNELQRIDYYNYGYLIITNKNGKLDKCSFYSSIIPSANNFDLIFNSSDSDTLTVLERFYFSGLEYKTRYFLYEDVSLPKALTSTYSNDKPYADRYSLLSNSKNNWAKDINNKELLFYLDISELKVFPTQNNFSAVTRNYLLTQYDYDYTDFQYNNANYPVFFNRLEVERSDMYDLTYRNQYKIFYQKVSE
>NC_017770.1|WP_014679472.1|1356717_1357557_+|hypothetical-protein
MKNYALYLLILCLAVTGCQKDIAENEVDLTAKKDKNCKCKKERYLPVMILEKSLDFLATDTVRIKYHDKKGNISCVTSSQRKGAIKFHYNNNNELQRVDYYDDGYFLITNKDGKLDKCSYYRSDSPSTPYFDLIFNSSESDTLTVLERYDDDTEYKPRYFLYTDVNLPQALTFSYTYSSSEYAYNIVSNNKNNWAKDVNNKELLFYISISGLYIFPTQNNISELQRYDFIFYKQSTYSNFQYNDANYPVFFNRLLVIATDIDEQYFNDQFKIYYEKVNN
>NC_017770.1|WP_014679483.1|1370915_1372895_+|OmpA-family-protein
MKRFLGMLTLVGFICSAELSYGQVEKADQEFEQLSYFSALELYKKAFEQTKTVPILQKIVECCKRTNRYKEWESWAAKLIAADNKNPDNYLTYGDALMRNGKYTDAKQAYYLYGRYSNGKLFESQFLQASCDSALNQMNSPITTATVKTLDVLSTPYSDWGLTKYRNGFVFSSDRPWEQKTIDKNEKKLYGWTGRPFLKIFYVESDPEKNSWGTPTLFSDFFNGEYHTAGAAFNERQNTVFFTRTRFVNTPETGTKPVLRLEIFMSEAWKEAKPFKYNSILKYSVGDPAVTSDGTRLYFVSDMQGGYGGTDIYYCDMGADGEWGPFKNAGPGINTKGDERFPTLMGDNVMFFSSNGRIGMGGLDIYRATQEKGEWKNVLRMDYPINSPQDDFSLVVTKISGVPENADKIKLEGFFSSDRFDSKGADDIYQFTCVMPQFQKEYYYKGRTMNKETGLPITNVTITVTDLSSKVSTTFKSNDKGDYEVPLKPNRQYEIVMKKNNYFASKQMFNTGDKLRMDMLQSDLTFDPIVLDRSIRLNNIYYDFNKSTITAESQAELDNLVGVMKENPEIIVELGAHTDSRGDAAVNLALSQKRAQAVVDYVVGKGIPATRITGKGYGKTKPLVMCEGGNECSEAEHALNRRTEFKVTRVRTDMAAATK
>NC_017770.1|WP_014679484.1|1372987_1374802_-|glycosyltransferase
MQLEKKLLVEIAWEVCNQVGGIYTVIRSKAPAMVDIWGDNYCLIGPMFPGKMPAEFEPTDKYNDAFGRAVLKMQKLGFEVHYGYWLVSGKPKVILINFAPIYSRLHEVKYFLWENHKIDTSSFDELVDQTIAFGETVKQLLEQLAQPGTTTKKIHAHFHEWMVGTPIAHIKKNALPIKTVFTTHATQLGRYLATTTPRFYDILPGVNWEKEARRFNCLSKVLIERSAAQNADVFTTVSEITGSECEILIGRKPDVITPNGINIERFVALHEFQNLHVEYKQKINQFVMGHFFHNYSFDLENTLYFFTSGRFEYVNKGFDLTIDAIDRLNKKMKKSGIDVTVVLFIITKQEYHSINSKVLHSRALMEEVRDTCTAIRKQVGDKLFLASAYNPDQKMPALNDFVDDYWKLRLRRTLLSWKNDELPYIVTHDLVDNHNDQIVNHLRRVNMVNEKNDRVKIVYHPDFISPTNPLFGLEYHQFIRGCHLGVFPSYYEPWGYTPLECIASGIPTVTSDLSGFGDYVLSNLPSEESHGIYIVRRRHNDYTKAAESLANMLFSFVQLTRRERISQRNMVESSSENFDWKYLVKYYRDAYQLIIEDDSVTEEI
>NC_017770.1|WP_014679485.1|1375034_1376390_+|pyridoxal-phosphate-dependent-enzyme
MKYYNNILETIGNTPMVKLNKLVEDIPATILAKVETFNPGNSIKDRMALKMIEDAEKEGKLKPGYTIIEGTSGNTGMGLAIAAIIKGYKCIFTTTDKQSKEKVDALKAFGAEVIVCPTNVDPEDPRSYYSVSSRLVKETPNSWKANQYDNLSNSQAHYEQTGPEIWEQTEGKITHLVVGVGTGGTICGTGRYLKEKNPNIKVWGIDTYGSVFKKYKETGVFDKNEIYPYITEGIGEDFLPENVDMEVIDLFEKVTDKDAAIYTREIVKKEGIFVGNSAGAAIAGIKQLKDKLTKDDVVVVIFHDHGTRYLGKMFNDDWMRERGFLQEEFITAKDLVKDHPAALVTIGSGEPVSNAIEKMKKYGISQIPVKRDGEFAGVLDESHLFRLMVGDNLTANKLIEDVMLPALPEVSGDDSIKKVTKHISHGHRAVLVKLDDGSYHIITQQDIITHI
>NC_017770.1|WP_042479379.1|1377042_1377360_+|hypothetical-protein
MNSFLKDIPPLLLQENGLNINEVVKRYSRLCTNFSNFIIPFLAIAVFFIRVNAIYNGNLEDSFASLSREQWVLWGGLMVFISGVMAVGTYYWLQGTYNKIMSWDW
>NC_017770.1|WP_014679488.1|1377444_1378641_-|acetate-kinase
MKIFVINSGSSSIKYQLFEMPAAKTICSGLVERIGLSDSIITHKVFTDGTDEVTIKNLDILDHAIGLQEVNALLTDPKIGVIHDTDEIEVVGHRVVHGGEQFAVTTIISPAVKEQIKKLFPLAPLHNPANYLGIDVAEKIFKKAKQVAVFDTAFHQTMPEVAFRYAIPNEFYYTHGIRAYGFHGTSHKYVSEQAATYLNKKDAKVITIHLGNGCSMAAVDSGKCVDNSMGLGPMNGLIMGTRCGDIDQSVIFHLVNQLGYDLDQVNTILNKKSGMVGLTGHSDMRDITAELQKGSKDAQLAYDMYTYRIRKYIGTFTAVLNGLDAIVFTAGVGENDALTRKLSISNLEYLGIQLDEEKNLKREKGIREINAVDSKVKVLVIPTNEELEIAQQCHKLLH
>NC_017770.1|WP_014679489.1|1378775_1380869_-|phosphate-acetyltransferase
MTNAIYIATSEPYSGKSVVALGLMNMLSSKAKRIAYFKPIVDDDPVKLKKDSTIQTIIRYFELEQDYTASYAFTRSEVFHLINMNKEADIIDAIIRKYKILEESYDFVLIEGSDFIGEGTAFEFDLNVSIAKNLGVPVIIVLSGEEKTIHEVSGAMRTAHNSFNDKEVQVLGVIANKIDSTQAFELTTLLKENLPARTIKSVIPGIKELSNPTMQEIFETLKGKLLFGENKLTNQVDNAIVGAMMLRNFLTRLRENTMVVTPGDRADIIISALQANISKNYPPVAGLVLTGDLLPDEPVLDLIEGLDSKVPIIATEKGTFETTNLIGSVRSRIYPDNTTKIELAINTFERYVDTKELDQRIITFEPEGITPRMFQYQLVKRAKKARKHIVLPEGNDDRILTAAARLVNQDIVDLTVIGNKDDIQAAVKRLALSVDINKFNIVKPTESEHFQDFVETFFDLRKEKGVNMDMARDMMSDVSYFGTMMVYKGLADGMVSGAVHTTQHTIRPALQFVKTKPGVSVVSSVFFMCLPDRVSVFGDCAVNPNPTAEQLSEIAISSAESSLMFGIEPKIAMLSYSSGTSGQGEEVEKVRKATEIVKEKRPDLKIEGPIQYDAAVDPTVGKQKMPNSDVAGQASVLIFPDLNTGNNTYKAVQRETGALAIGPMLQGLNKPVNDLSRGCTVDDIFNTVVITAIQAQE
>NC_017770.1|WP_014679490.1|1381042_1382227_-|aminopeptidase
MNVKYFLVVPLIALATAVNAQDNLIKSLENNQSASSKEGFNFTTVTNAEATSVKNQGSSGTCWSYSTNSFLESEMIRLGKKPVDLAEIFTARNAYIEKGVNYVRMHGAISLGDGGACHDVINMYAQYGALPQDVYTGLNYGTKKNQFKEMAAITEAVLQAVVKNPNGELTPNWKKAYTAVIDSYLGEVPATFTYEGKTYTPQSFAKERVGINPKDYVELSSFINKPYYEKMLLMVPDNWSLDQVYNVKMDDMINIIDNAVKKGFTVAWATDVSEKGFSWKNGVAYVPAKKFEEMTADEKGTMFNGPREEMIITEELRQAAFDNYNTTDDHGMQITGLAKDQNGKEYYIVKNSWGETNDYKGYLYVTKEFVKYKTTAFLLHKDGIPSDIKKKLGL
>NC_017770.1|WP_052308554.1|1382736_1383093_-|NAD(P)H-dependent-oxidoreductase
MKILAIPGSLRNNSSSNKILDFISTITPEHVDFQVYDKLAAISAFDDSDEVPQAVLHFKRAIKEADVLLICTPEYAFGVPGALKNAIDWTVSSGEFVEKPVALITASSQGEKGTRCPS
>NC_017770.1|WP_014679491.1|1383123_1383771_-|LysE-family-transporter
MEQLYIFAIAFVASFIGSLQLGPVNLTVIQTSVNKNFKAAFWVSIGGCLPEILYALIAVAGTSLIDAKSSFFTYAGFFMVPLLLGLGIFKIIKYKEPENTEPQEYPSTLFGDFMKGFMLSIVNPLLLPFWSTVLIYNTSIHVFSLDNKMEKSLFVFGAAAGALGLLMLFAGVAHWKKERINKLVNGNINKAIGWVFIVLGLIQLVVFGLRYKHLI
>NC_017770.1|WP_014679492.1|1383818_1385135_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MSAFEIIGGKKLKGEITPQGAKNEALQIISAVLLTEEKITISNIPDIVDVNKLIDLLKDLGVNVERISKDTYTFEAKNIDLEYLNSDKFKKKGGALRGSVMIVGPLLARFGKAYIPKPGGDKIGRRRLDTHFLGFEKLGAKFNYNPVDHFFSVDASDLKGTYMLLDEASVTGTANVVMAAVLAKGTTTIYNAACEPYLQQLCKMLNRMGAKISGIGSNLLTIEGVEKLGGTEHRMLPDMIEIGSFIGLAAMTKSEITIKNVAYEELGVIPEVFKRLGIKLERRGDDIFIPSQEVYEIETFIDGSILTIADAPWPGFTPDLLSIVLVVATQAKGSVLIHQKMFESRLFFVDKLIDMGAQIILCDPHRANVIGLGRRNQLRGISMTSPDIRAGVSLLIAALSAEGKSTIFNIEQIDRGYQDIDVRLQALGADIKRITVNE

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Crispr_ID: NC_017770_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_5

2540699-2540790

Orphan

Consensus_repeat	Method
GGCTGAAGTCAGACGGCAATGAAGCTCTTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_5

>merge|NC_017770|5|2540699-2540790|CRISPRCasFinder
GGCTGAAGTCAGACGGCAATGAAGCTCTTGTTGAATCATCTATTATAATTATCCATTCCGTAGGCTGAAGCCAGACGGCAATGAAGCTCTTG

>NC_017770|5|4|2540699-2540790|CRISPRCasFinder
GGCTGAAGTCAGACGGCAATGAAGCTCTTG	TTGAATCATCTATTATAATTATCCATTCCGTA
GGCTGAAGCCAGACGGCAATGAAGCTCTTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_157604552.1\|2529608_2533355_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680425.1\|2522567_2526638_-\|DUF4157-domain-containing-protein	unknown	unknown	gnl\|CDD\|379338
NC_017770.1\|WP_014680441.1\|2547951_2549040_+\|alkaline-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366752
NC_017770.1\|WP_014680427.1\|2528338_2529604_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680436.1\|2543958_2544402_-\|phage-tail-protein	unknown	unknown	gnl\|CDD\|377718
NC_017770.1\|WP_014680423.1\|2520399_2520963_+\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|379205
NC_017770.1\|WP_014680434.1\|2542847_2543543_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680426.1\|2526723_2528313_-\|DUF4157-domain-containing-protein	unknown	unknown	gnl\|CDD\|379338
NC_017770.1\|WP_014680440.1\|2547095_2547647_-\|DUF4255-domain-containing-protein	unknown	unknown	gnl\|CDD\|379449
NC_017770.1\|WP_014680432.1\|2540366_2540657_-\|PAAR-domain-containing-protein	unknown	unknown	gnl\|CDD\|269823
NC_017770.1\|WP_014680429.1\|2533365_2536434_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274051
NC_017770.1\|WP_014680430.1\|2536433_2539928_-\|baseplate-J-like-protein	unknown	unknown	gnl\|CDD\|274051
NC_017770.1\|WP_014680439.1\|2546330_2547086_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680437.1\|2544401_2544836_-\|phage-tail-protein	unknown	unknown	gnl\|CDD\|377718
NC_017770.1\|WP_014680431.1\|2539946_2540363_-\|GPW/gp25-family-protein	unknown	unknown	gnl\|CDD\|377431
NC_017770.1\|WP_014680442.1\|2549139_2549700_-\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|369881
NC_017770.1\|WP_014680433.1\|2540816_2542592_-\|type-VI-secretion-system-tip-protein-VgrG	unknown	unknown	gnl\|CDD\|273730
NC_017770.1\|WP_014680438.1\|2544885_2546298_-\|phage-tail-sheath-family-protein	unknown	unknown	gnl\|CDD\|226028
NC_017770.1\|WP_014680435.1\|2543542_2543716_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680424.1\|2521065_2522514_-\|DUF4157-domain-containing-protein	unknown	unknown	gnl\|CDD\|379338

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014680425.1\|2522567_2526638_-\|DUF4157-domain-containing-protein	gnl\|CDD\|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	1.38446e-36
NC_017770.1\|WP_014680441.1\|2547951_2549040_+\|alkaline-phosphatase-family-protein	gnl\|CDD\|366752	pfam01676, Metalloenzyme, Metalloenzyme superfamily. This family includes phosphopentomutase and 2,3-bisphosphoglycerate-independent phosphoglycerate mutase. This family is also related to pfam00245. The alignment contains the most conserved residues that are probably involved in metal binding and catalysis.	2.90713e-05
NC_017770.1\|WP_014680436.1\|2543958_2544402_-\|phage-tail-protein	gnl\|CDD\|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	4.40617e-48
NC_017770.1\|WP_014680437.1\|2544401_2544836_-\|phage-tail-protein	gnl\|CDD\|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	1.57355e-59
NC_017770.1\|WP_014680426.1\|2526723_2528313_-\|DUF4157-domain-containing-protein	gnl\|CDD\|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	2.95587e-35
NC_017770.1\|WP_014680432.1\|2540366_2540657_-\|PAAR-domain-containing-protein	gnl\|CDD\|269823	cd14738, PAAR_2, proline-alanine-alanine-arginine (PAAR) domain. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family, where it forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). The T6SS is responsible for translocation of a wide variety of toxic effector molecules, allowing predatory cells to kill prokaryotic as well as eukaryotic prey cells. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes. It has been shown that PAAR proteins are essential for T6SS-mediated secretion and target cell killing by Vibrio cholerae (encodes two PAAR proteins) and Acinetobacter baylyi (encodes three PAAR proteins); inactivation of all these PAAR genes results in inactivation of Hcp secretion as well as T6SS-dependent killing of E. coli.	2.60793e-41
NC_017770.1\|WP_014680429.1\|2533365_2536434_-\|hypothetical-protein	gnl\|CDD\|274051	TIGR02243, hypothetical_protein_SCD8A.17c, putative baseplate assembly protein. This family consists of a large, conserved hypothetical protein in phage tail-like regions of at least six bacterial genomes: Gloeobacter violaceus PCC 7421, Geobacter sulfurreducens PCA, Streptomyces coelicolor A3(2), Streptomyces avermitilis MA-4680, Mesorhizobium loti, and Myxococcus xanthus. The C-terminal region is identified by the broader model pfam04865 as related to baseplate protein J from phage P2, but that relationship is not observed directly. [Mobile and extrachromosomal element functions, Prophage functions].	5.44351e-06
NC_017770.1\|WP_014680430.1\|2536433_2539928_-\|baseplate-J-like-protein	gnl\|CDD\|274051	TIGR02243, hypothetical_protein_SCD8A.17c, putative baseplate assembly protein. This family consists of a large, conserved hypothetical protein in phage tail-like regions of at least six bacterial genomes: Gloeobacter violaceus PCC 7421, Geobacter sulfurreducens PCA, Streptomyces coelicolor A3(2), Streptomyces avermitilis MA-4680, Mesorhizobium loti, and Myxococcus xanthus. The C-terminal region is identified by the broader model pfam04865 as related to baseplate protein J from phage P2, but that relationship is not observed directly. [Mobile and extrachromosomal element functions, Prophage functions].	0.000350938
NC_017770.1\|WP_014680442.1\|2549139_2549700_-\|PAS-domain-containing-protein	gnl\|CDD\|369881	pfam08447, PAS_3, PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.	2.13064e-10
NC_017770.1\|WP_014680423.1\|2520399_2520963_+\|PIN-domain-containing-protein	gnl\|CDD\|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	1.81315e-10
NC_017770.1\|WP_014680431.1\|2539946_2540363_-\|GPW/gp25-family-protein	gnl\|CDD\|377431	pfam04965, GPW_gp25, Gene 25-like lysozyme. This family includes the phage protein Gene 25 from T4 which is a structural component of the outer wedge of the baseplate that has acidic lysozyme activity. The family also includes relatives from bacteria that are also presumably lysozymes.	2.29962e-33
NC_017770.1\|WP_014680433.1\|2540816_2542592_-\|type-VI-secretion-system-tip-protein-VgrG	gnl\|CDD\|273730	TIGR01646, conserved_hypothetical_protein, Rhs element Vgr protein. This model represents the Vgr family of proteins, associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region, VGXXXXXX, found in the Vgr of Rhs classes G and E.	2.05173e-38
NC_017770.1\|WP_014680438.1\|2544885_2546298_-\|phage-tail-sheath-family-protein	gnl\|CDD\|226028	COG3497, COG3497, Phage tail sheath protein FI [General function prediction only].	1.52776e-47
NC_017770.1\|WP_014680440.1\|2547095_2547647_-\|DUF4255-domain-containing-protein	gnl\|CDD\|379449	pfam14065, DUF4255, Protein of unknown function (DUF4255). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 320 amino acids in length.	9.76033e-37
NC_017770.1\|WP_014680424.1\|2521065_2522514_-\|DUF4157-domain-containing-protein	gnl\|CDD\|379338	pfam13699, DUF4157, Domain of unknown function (DUF4157). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 80 amino acids in length. This domain contains an HEXXH motif that is characteristic of many families of metallopeptidases. However, no peptidase activity has been shown for this domain.	7.64944e-36

>NC_017770.1|WP_014680432.1|2540366_2540657_-|PAAR-domain-containing-protein
MSLAARVSDMHVCPMVTGVVPHVGGPILPAGVPTVLIGGLPAATVGDMCVCTGPPDLIVKGSSSVFIGGKPAARMGDTTAHGGTIVIGCPTVIIGG
>NC_017770.1|WP_014680431.1|2539946_2540363_-|GPW/gp25-family-protein
MDAKRSFLGTGWGFPPQFDDITSAVVMISDVEDINSSLGILLATRQGERVMQPTYGCNLDELVFEPLTTTFKTYIKDLIATAILYYEPRIDVNKIDLDDSEELQGKILITVEYTVRSTNSRFNFVYPYYKTEGTEIRK
>NC_017770.1|WP_014680430.1|2536433_2539928_-|baseplate-J-like-protein
MACNEKNPLQREGTSVLTRVLSALSTSFAKADERQAADILLFLRRYSTYLNYYNTTNSLAGDWEPFMKMDISVTLAFLMRLDSRKCSDYKKLVYKKIRLSGTDAEVKKEFKYVFDLLFSLLKIVTEQYHLLPESYEFKQEIENLIKTKLLLPAVNLKKLYDNFNTDGLLNTGTDIDSAAPINTASSSSFALTDLGTEWTLPLPVTGLTVPPSLPSVKDKVVYSINHNFFNAQIESLLKAIATLAEKSAVLFEKTLEDYPSHTPHYALVIAFVKLFAKAQDELNNYTKRHLDFYYKEVLQLVNKKAETDKAHLLLELQKPVPKHLLTKGTLFKGGKDSITGKELSYALVEDVVFNKAVVEQIQSIQFLNKSKELLVASPISASEDGQGAKLVSVDKSWFTFGNPETIKEATTGFAIVSNLLFLNEGQRTVTITVTFANGTTTFADTSSLPHSRFFKGELTGNKGWHTVDLQVIGNSIGDQLTFSLTLSPDDPPIIPYTENIHKESIETDLPILKIYLNQSSAFSYPYRLLTKDRINTIQVAVDVVGVRNLQLSNNTGSVDASKPFKPYGEFPDSDALFYIGSKEIFQKSLTEIQFVFGEKIPYNSQIGYLYQGNWVAISGTSAGVDAFNLNSNYIPSAKDFSENEPLASTTLTGFIRLQIGVSDYSKDTYLSAVQTQINSTTISQTTDTTPTYKINTGPIASPPELNLSAFSINYKATVVIPLNAVNTNSNNRFLHLAPFGYYEVAFDNALPSAKISLVAQMDNNGELFIGLDNTEPEEVVNILFQVAEGSSNPLKNEEKLLWHYLAVGNKWIEFESKHIIDRTNNLTQSGIVTATLPLTISNQCTAQQKGLYWIRIAAKQNPDAVCKLMMVQAQAAQVTLVQDETKQIEFSQTLRAGTISKLVVSESAIKSIVQPFDSFGGRTRESDEHFYTRVSERLRHKQRAITIWDYEHIILEQFPQISKVKCINHAGFYTETDNSEVFCENFPGHVTIITIPDFRNKSGINPLKPYTPIGTLVNMDAYLHKLISPFVKLHVKNPQFEEVQFEFMVSFYENLDNSFYRQLLDKEIEKFLTPWAFDISNEISFGGKIIKSEVLNFVEERPYVDYVTCFKMHHIIQRNGAVHTIEKRDVEVAIPSTARSLLVSYTNEITKITHLIDSPATCEC
>NC_017770.1|WP_014680429.1|2533365_2536434_-|hypothetical-protein
MEEKTTISKNRKLPQAMDYELLRKEGLRHIESLSSDLWTDYNVHDPGITILEALCYAITELGYRCQFDMKDLLSDVNGNLVSGQTFFTAKQILTVNPLTINDYRKLLVDLAGVQNAWLIAEDVQMVNGKTVPVNEVPIYADCINDQLIYTPNEHPLFLSGLYRVLLSLDYDDQFGDLNDGDIVTGNPELVGKYVENEFYFSIELDAWKNADFDFAQLAKDKTKIQSAVLSAGKNGWTCALTVSGVPNPKVFGVTISKLPESGKLSEADAQSMFDNKDWVAGIFAQYLSKIKLAQTIVKSAIKTLHEHRNLCEDFVEVTTADTDQIAFCFDTDVRPDADIEKVQAEIFYLIENYLNPPVQFFSLKELLEKKVPVDEIFNGPVLQHGFIDTIQLESTNLKKEIYASDIINLLMDIEGVIAIRNFQMTKYKENGEPDNAFKNLKWCMPVKPFHKPVLRTDKSKILLFKNEFPFIARYDEVKDTVLLLHAIRSRNKLSGLQDDIPVPKGAKRDTESYWPVQYDFPLVYGIGEAGLAEGVTPERKAQQRQLKAYLLFYEQLLADFFSQLSFSHELFSTDKIKHTYYAQFLADIKNIETIYKPNVASAILNDAISDPDATKAEKNEWQKLYETKETFEDRRGRFFDHLLARFAESFNDYALMMYTINYEEQTEEKISFEELSTAKILTLQQYDDISANRGKAFNYFPQIVQVVGDDVQFLPDPTKYWDTDNVSGLEKRICALTGIKDHKRRFLYCIKQIEIICTEKEVLVEGNKVLKCFHSFTVTPLNGTQLISKEYEIKTDAEAALADVINGGAVKTNYSVITVGGKFKISYKDILTGVNEYNSQGDATTAINEIALEFEGTCNDPEGLHLIEHILLRPRTNQFDLMQVCLHDCDCPCEIDPYTFRASVVLPYWPGHFDNPAFRSYFENRLREEAPAHVMLKICWLNNDLMREFEVRYKRWIELLAAYSFDKIANEADFMDANNKMIEILERLHSEYPQATLHNCDESKEGSNTVVLNKTVLGTFKT
>NC_017770.1|WP_157604552.1|2529608_2533355_-|hypothetical-protein
MQTSFPVFDADQVLTNNHLNDLRKYLDEQNRLTRSKLIGSGIVCGLEITVSSSAIKISKGCGLTSQGFLITLCDSEYTHCIPYTAPEFPEDFDFISQCGNGVPGSVPFYKPGFTEPMLQLISAKELEGLSTEIKNTAVALSAMSVQTLSELAVVLFLEAEQIKLKNCDTNDCNDKGSRMDFEPKVLLVQKAVLDRINADSKGQVTKNNLPHVELKRYNVPVRNLLTTSAVLAAFADITNDATIDKIDEALNSSFTNYSYLLDEQGGNPFGGVGNTLKSIRQKIVTTNPLFIQYFYDFLDDLIKAYYEFREKAYYVYSECCMDEMRFPLHLMLGEATVNTLPGKQSAYREFFIYSPLFDAQNYRLGEVRFLFARLKLLIQNFSTDDATLFEKRVIKITPSNLGKSHLSERCIPYYYNVIGGANQPALFKFWNYKKTLHGEADYNLSYKSNEYADPTNLLVRDPLLFDIEKYNFFRVEGHIGKQVGVALPGIINIKQEYNLPAEVIALSADYIGAILKGEEPQCVIQDLEADYRIIIAEFICKLHDAFCSIYRFDFSPKPLELVAVRSKAKAVAAAATNEEDEDLEVNELIGKTDFDGLAVNHPVLSRLVSEAHITKNYVKGSSILRICGVRKGSIGDIYLSNISDNIFTNPISLNTKIRAASLYFRFFELIDSIESMFKILLNNELSELNLTEFKNAYIRYEKEVKNLAKQLRVITDKVQVFLSTCIVEKLEALKDEYRRRMNQYALARKFNNYFKAHGGIEHKAGVSKGGTFILVYYEETRNRRFDISALFVNKNLGRLMLAKHPDLLARDVPDAELKAATEELQTAVEFKCPEQFTFLTNAVKDYLKTDINIPEASREALLAALRKAPERPGFSFASGTVIADFYVPYICCSDCTPVSYVLQPPEPLPLSVFADQPICNTEGTSYSVRLEVSGGTGPYTFIVNNVEQTNNTIVLASGSPDTKVTVKDAAGKTAEIVIKSHTCQPPCNLPCDGNSQACRYILWVAKPVGTRIVHETRGAKLRLVDENNQETVINLMPVFKEVFESVHNVILATNFDSIFKALTEKINNVIPAKFIGNNKPMFTYDAENQLWIIDKFDCHEVTLTLEVFMSFSDEQLILNIIYDKDGVTIVDTQRQTKVIVPPFGCVQVNKCTGKVVNKCNETLKIDEIKGSQVEFNQPFFNFSTKPIFDKYFWYFHTGIPLYSDQVAPQKVQLLPSQEQPTVRVIGIKSSNGCFALLETKVALDIIVG
>NC_017770.1|WP_014680427.1|2528338_2529604_-|hypothetical-protein
MKAGAHIIQRQSIDIQFENMENDNGLQNRLADLFYDRLEPGMEQLLDELFGEKYYASVEKLEIECEVLNEKDWEEGLAEQIIQKLREKLSPVNKREIKDAKVEELTAPEIFLFFLENGSFPWNNRVNSINELEQLISVNNELLAKLTEKIKEYPKIAERLALQFSEKFTSTVITELTKERQWERSELNSRISKLDSTLNRQAVDGAILKMLASDHHDNPTEQLLEKLVDKALAKNKAIDEKIDKTIDKNINKKEDNNCYITNAGLILLHPFLSILFEQLKLIHENEWIDELAQTKAVLVLDYLVTGNEKAAEFNLMLNKILCGFAINNIIRTDVALDHEAKNECETLLKNVIVHWSALKNTGIDALRETFLQRNGKLSPVDNGWLLTVEQKSTDILLGYLPWGFGVIRLPWMKEIVHTDWC
>NC_017770.1|WP_014680426.1|2526723_2528313_-|DUF4157-domain-containing-protein
MQTHVTGITEKIGNTVNSNQQKNKPFFAPVIVQPKLTIGPVDDPYEREADSVAEKVMRTPEQDVLQAKPSPIVIQKKCAACEEEELNRKEDEAPAVADELSAIKDIPVQRKCAHCEEEERNLQMKGADGAKGGLGALSIVNQVINSQGEPLHAATRSFMESRFGYDFSNVQIHNDLLAHQSSTAINAKAYTHANHVVFGSGQFQPDTNAGKQLLAHELTHVVQQRAGQQQAVQRRIGDGHDLNAARFKGNIVLEALYDNEQLLRKGDKGPAVKILQQALIDSGMTLPVYGVDGKFGAETENAVKTFQRASGLSGIDRDGVVGPTTMGWLDQRFTNSPTPAGTSRGATTGCPAFKTIKVDFVSFRGSTRNPGADLDYANTVFNQCCVKFEMGKGFSLSNAESDIILKGNTELNVANSCAALSAEESSLVAKLSPRVSSRFKVFYVDTISTGDRAMSFPPYCATGLAASRLNFSFVSNSAMPRSLAHEFGHILLNSPGHAPGVTTKLMHPTNAATAEDLDATDCATVFANA
>NC_017770.1|WP_014680425.1|2522567_2526638_-|DUF4157-domain-containing-protein
MQTCITAISAKSGIKLINSSKQKKPFFAPVILQPKLTIGPVDDPYEHEADATAEKVMSMSDNREVAAKPAPLVVQKKCAACEEEELNRKEDNEESEPLEPNPIKDIPLQRKCTHCHEEDRKVQMKGIEGVKAGMAVPSVVNEVINSKGVPLDAITRAFMEPRFGYDFGNVRLHNDSIAHQSSAGINALAYTHGNHIVFAAGKYQPNTVSGKRLLAHELTHVLQQNPSIQTHQISHNTDLGTIQRKETPGTETDIFSGDKSSKCPKVPTNEGFIFPDPPCPIGTHIGSKAMKRFNFCADSSTLIDPNQLNDLDKILETNFKSSRFLIHGYASLEGNKDYNFVLACRRANTILEALSATMRRNSMDKSKTEQDAEISRRIETASQGPTKEFGNTPEANRIAILYLQEPLGEAPDEPACKDAPKNIGDVKPDIDCDQPTMVLEGTEASLQRRFFFFCTGSDVFLGETAKNVKTFAHKQAASASFTIHGFASEEGTKDTNKRLSCHRALRVARELMNAGVLSEQIKEVSGIGATDKFAKGNNETAFSQNRVVVIHVDEGRINPLNDKPKEAKTAEQKAALIKEAAKILLSGQYNLGADAYLSFWTCGTTQTVRQAVTRLHIQSPLGDKDELLTVDADGVEEGIGVNTVRLSNTSLRADNPLECIMGRLIDMAFHHAVINNDVLTSNKNLLEDDNSQTISRLRKDKKMRHEVGLHLVFLAGFSACLGTQASAGKSPSGKSTGVSEPIEDDPLQLMEPPLCAAVPQPSRLLSPPKGAKKREKTVFKPQNTDFGLEQKGAHESIRIAPKKSTGPALNQNLTIKTAEASPVIKPSSTVSLVGNENVFNDYEIGFMQSILDDLTIAQYITGHEVVQKLPVPTRAAEIKGNPQVPLPWMSMNAMQRPDPEGQVKLNSTWQMDSNFALTLGFFNDNPIVNANFLDTLQHHTKIAIWLVARRLGGPLDRFTVIPMEGKVYEIAQNIKVDFKRKRGNLDLPENDPLNQGEVENVLIDGVFRTIETSDAAADFRLARFGTPTAGNIDLNRQFVSMVGPGKAPSGGEGMDLPEYMALIKQIVDTLKVFTEEEIANNQAGKDMPRLGYVFDTLTITVRINPNTGRMLPYSEIDNERENRSVLIDSPGIGKNGLNGLSKALGLRLEKLDQQNQAKKVILNTEAIKKLSSDQNGTFLRFTLPPLIAAKDEKRLIEEPGVKEQMALLWACTELLLSDDDPFNKGGLEPREFALVYWKDRDHTLHRDPEDAVYMGKPLNMATGVIETNIPCGAIRASGMIVGNVHTHPFDDKDAPKPSPKDQANARSGHCGRQFYIISQRFVFEYFSDDNEPKKIGTRESVLPKGVRCDTKAKELP
>NC_017770.1|WP_014680424.1|2521065_2522514_-|DUF4157-domain-containing-protein
MNKQRLIRSAPSKGSIFFKPRMQSKSIISQPNDSDEQEADTVAEKVMGGGNSESTQTFFKPAVSQIQRKCDSCEQGGKLQLKSDSNHNSTSEVSSGAFKVINSAGQSLDNPTKDFMESRFGHDFSNVHIHDDSNAHESSTAINALAYTHANHIAFAAGQYQPQTDAGKQLLAHELTHVIQQTKAGNPRIQRACADKSVRSQAWVSVKNQHDFAALDGYTPIKGKVYDVFFDGKSYFFCYNDKRVYFKYANTKDRVIPDLETAYNIKVETGGAKWLKSELVLISEALSMLNDTEIANLRGYRFIKQGDVMIEDGDKVVAGLTTQDIIRNEYTIEFWKFCFDGTSDTPVGTKAGVTPGVPCILHEIGHAMMYARSRPYMEAMYFQNKYQKEFDKASADKQKGMKPKLDELKRIHDKAEAAYNKNPSVESEFVKLVKGKPPLTPYSKKNEREAFAEAFAIYKLNPDLLKKKNLKLYQYFKSSGFK
>NC_017770.1|WP_014680423.1|2520399_2520963_+|PIN-domain-containing-protein
MIAILDANVLYPAPLRDFLMHLANVKLYQPKWSAQIQEEWVRNLLIKRPDLNMNGIKRTVDLMNEIFPDANVNGFGNLIDGLDLPDPDDRHVLAAAIKSKSKFIITHNLKDFPNTVLKDFNITILHPDDFVLELIENNDVLVIEAFMNQVKKLKNPSRKVPEVLDTLYNQGLKKTVEQIKVKLKIFD
>NC_017770.1|WP_014680433.1|2540816_2542592_-|type-VI-secretion-system-tip-protein-VgrG
MASTDNTVLVEDKMDVVTLLIKVDGEEISRQYHVTSLTILQEINKIPTANLVVIDGEASKQDFSISSTGQFVPGKKIEIELGYFRNGQSDDDKFLFTGIIVTNTHKINNNCCELTIECKDETIKMTVNKSNAHFKKKITASEIAEELLNKNNISTEKVASIDLKHEQLVQSNISDWDFMIGRIDVAGMICVISSAGVKIKQLAIQNPPTNESGEMLKLIHGKNILEFSADKDSRIRSDEVKTLCWDFKEQKVRVSGNDEKIVEEKEDQSKNVSKGFEMRSAAFFTEEEQTVLAKTKKIKQDLSGIKGKVKYIARTDITVLPGDFIELSGVGNAFEGFHFVSAVQQEYTDGCWITEATLGWNEQFFSEQTNPQHSASTTGQPSTVQGLQIGIVTNIEDSDGEYRVQVKLPVVDDKAEGLHARVATLDAGNKRGTFFRPEIDDEVIVGFINDDPSNPVILGMLHSSAKSSPLEPKKNNNEKGYVSRSEIKLLFDDDKKSVIIQTPGSRSFEMNDDSGTITLKDGNGNKIVMGSSGITIEASKEIKIKAGTSLSLEAKKISIKSDTSLEAQGSASVKISGGGATEIKGGVVKIN
>NC_017770.1|WP_014680434.1|2542847_2543543_-|hypothetical-protein
MALEFGKIEKLYIQAYKDPDLNEPVGGKFYALINPETYTYKYKIEFCDTQAPGTSGVALKFNKMPPQDFNFDFLFDRTGAFKDAATENSSVSSLTVAEQLDDFKKKIFEYNGEKHRPNYLKIIWGTLLFKGVLIALDIEFKLFKPDGTPLRAIAKCTFKGTVTEELRVAKENSQSPDITHERIITASDRLSLMTHNIYNNQDYYTDVAAFNRLDSFRKIKPGERVLFPRID
>NC_017770.1|WP_014680435.1|2543542_2543716_-|hypothetical-protein
MPIEIKELHIKAIITNRDKETNSGASFKQEDINKLKKEITKEVTDKVLRILRQKSER
>NC_017770.1|WP_014680436.1|2543958_2544402_-|phage-tail-protein
MIEYPPVGFHFLVIFQLFPESPNDSRFQEVSGLDAEIEMESFAEGGQNRFTWQAPKRTRYADITLKRGMFIGSGILLWCRNALENFVFEPVNLTVSLLNEQHVPLQSWYIVNAIPKKWSVSGFNAQENSIVVESITLSYQYFNIISV
>NC_017770.1|WP_014680437.1|2544401_2544836_-|phage-tail-protein
MAQYPIPKFHFQVEWGGAKIGFTEVTGLEVSTEVIEYRDGASPEYHKIKMPGMQKFSNITMKRGTFQGDNDYYTWWNTVALNTIERRNVIISLLNENHEPVVVWKIKNAWPVKVQSTDLKADGNEVAIETIELAHEGLTIQNEA
>NC_017770.1|WP_014680438.1|2544885_2546298_-|phage-tail-sheath-family-protein
MNESAIATPGVYINEISVLPPSIAQVSTAIPAFIGYTEKAVDEQGIPLVGIVPVKIFNLKEYEQRFGKAENEKNITVDVTLTTTPSVSVTAVAKLAAAPNAHNMYYALRLYFDNGGGPCYIVSVKPSSTVGISDTDLDNGIKALEAYDEPTLFVIPEGQAIATPATFYALMQKAVNQCAKLQDRFTLVDVVDNTAVDTTTNINNFRTTVGLNKDLNYAAAYYPNLKTNYEYQYLENQVKVKLVKNGGPATNTFLNALLPNESIAYYAARDAIKRTLNPVLPPTPAIAGVIAGTDANRGVWKAPANVPLVSVLDVMDFVTDDEQASMNIDPGTGKSVNAIRPFNGKGIVVWGARTLDGNSSEWRFIPVRRFFIMVEESAKKATAQFVFEPNDANTWTKVRAMIENYLTLLWRQGALAGAKPEHAFFVKCGLGQTMTAQDILDGKLIVEIGMAAVRPAEFIILRFMHKLQES
>NC_017770.1|WP_014680439.1|2546330_2547086_-|hypothetical-protein
MTVFTIQRVGETVKIIYRELFVIKFAHPAYETPQKSFIDQHINIAADAATTELFLNNRISYQFSQNTLTCFVETAFFNPPTEEPKIPLITMPADMKIRFLLYSSSDFLAKTYVVATGSKEAYRFSNQVNNISGGFTLLTTPVENHSAAKDYSIGTLVKSGSNLFSPIKTVLASQSIALSDTAFWKKLPGVEQVASNADLKDSAAILLDVNCFAAIDIQRTGVINNSYKVLDTGDKLFNPAPVFTIRFKSRI
>NC_017770.1|WP_014680440.1|2547095_2547647_-|DUF4255-domain-containing-protein
MIFPAVNIIQQELSNELSSFPVTVDLGNITEIVNDLSNGANSDIIISLINIEENRISRELDYYVKKDNTILKKNPAIHLYFTLLFTSVKPTSAYGMSLQNLQHVIEFFQKKFVFDHSNTPALHPNIEKLILEMVTLNLQQLHEIWSVLGGKYYPSVMYRVRMVTIDSITDMEGPPVKEIILNF
>NC_017770.1|WP_014680441.1|2547951_2549040_+|alkaline-phosphatase-family-protein
MKKLLLLTFSAFILNIAIAQPKLKTRNIILITLDGFRWQELFKGADSTLINDKDYTTNFGRVSEQFWAETPQERRQKLMPFVWQTIARNGQLYGNRDLNNKVDMTNPHWVSYPGYSEILCGYVDTLIRGNKKRNNPNITLLEFLNNRHEFNGKIAVFGSWDVFPYIINQERSKIPVNAGYAKVEGDHLSTSTKLLNTMQKQVPTVFGGARLDVFTHYQAKEYLIKHHPRVLFIGYGEPDEWAHQGNYEYYLQSVNNIDQFISDIWNYVQSNTFYKDKTTLIITTDHGRGEAQKGKWKSHGINIIGAGEVWLAVIGPDAKPLGEVKSEGQLYSTQIAQTISKLLGINYMNTRSVGKAIDSVIE
>NC_017770.1|WP_014680442.1|2549139_2549700_-|PAS-domain-containing-protein
MIKPIPVNKEVAWDKSKTIMSKTDPRGVIEYANDAFIEVSGYEEHELMGQPQNIVRHPDMPKVIFKILWDNLKAGRNMHAIIKNLAKNGRYYWVITDFEVKLAGGDIVNYYGKRRAVPQPVITDLIEPLYEKLIQIEKVGGVAASEKYFNGFLEEKGKDYNAYIKGIITESDKSGDKKGFFARFFD

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Crispr_ID: NC_017770_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_6

2676346-2676457

Orphan

Consensus_repeat	Method
CGCAAAGTTTTATAGAAAGGCTGTCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_6

>merge|NC_017770|6|2676346-2676457|CRISPRCasFinder
CGCAAAGTTTTATAGAAAGGCTGTCCACTTGAAGGATGGCCTTTTTTTGTGGATATATATGAGGGAAAAGGTATAACCGCTAAGGCGCAAAGTTTTATAGTAAGGCTGTCCA

>NC_017770|6|5|2676346-2676457|CRISPRCasFinder
CGCAAAGTTTTATAGAAAGGCTGTCCA	CTTGAAGGATGGCCTTTTTTTGTGGATATATATGAGGGAAAAGGTATAACCGCTAAGG
CGCAAAGTTTTATAGTAAGGCTGTCCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014680541.1\|2671744_2672875_+\|tRNA-guanosine(34)-transglycosylase-Tgt	unknown	unknown	gnl\|CDD\|234642
NC_017770.1\|WP_014680547.1\|2680272_2680722_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NC_017770.1\|WP_014680545.1\|2676966_2679816_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223893
NC_017770.1\|WP_042479688.1\|2669117_2669741_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NC_017770.1\|WP_014680550.1\|2683344_2685444_-\|HEPN-domain-containing-protein	unknown	unknown	gnl\|CDD\|223233
NC_017770.1\|WP_014680546.1\|2679935_2680199_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680553.1\|2689323_2690199_-\|DUF4349-domain-containing-protein	unknown	unknown	gnl\|CDD\|379526
NC_017770.1\|WP_042479691.1\|2670378_2671506_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133035
NC_017770.1\|WP_014680536.1\|2666469_2667819_-\|ammonium-transporter	unknown	unknown	gnl\|CDD\|223083
NC_017770.1\|WP_014680539.1\|2669782_2670388_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236608
NC_017770.1\|WP_014680552.1\|2686090_2689018_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|372685
NC_017770.1\|WP_014680544.1\|2675415_2676321_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_017770.1\|WP_014680548.1\|2680978_2682535_-\|TSUP-family-transporter	unknown	unknown	gnl\|CDD\|224562
NC_017770.1\|WP_014680542.1\|2672926_2674213_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|379262
NC_017770.1\|WP_014680535.1\|2665712_2666204_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|224973
NC_017770.1\|WP_014680551.1\|2685727_2685871_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680543.1\|2674313_2675429_+\|YjgP/YjgQ-family-permease	unknown	unknown	gnl\|CDD\|367632
NC_017770.1\|WP_014680554.1\|2690264_2691437_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181244
NC_017770.1\|WP_014680537.1\|2667913_2669008_-\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|376794
NC_017770.1\|WP_014680549.1\|2682534_2683317_-\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|381169

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014680541.1\|2671744_2672875_+\|tRNA-guanosine(34)-transglycosylase-Tgt	gnl\|CDD\|234642	PRK00112, tgt, queuine tRNA-ribosyltransferase; Provisional.	0
NC_017770.1\|WP_014680547.1\|2680272_2680722_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	4.08768e-38
NC_017770.1\|WP_014680545.1\|2676966_2679816_+\|hypothetical-protein	gnl\|CDD\|223893	COG0823, TolB, Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion].	1.71922e-06
NC_017770.1\|WP_042479688.1\|2669117_2669741_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	5.60562e-65
NC_017770.1\|WP_014680550.1\|2683344_2685444_-\|HEPN-domain-containing-protein	gnl\|CDD\|223233	COG0155, CysI, Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism].	1.07612e-101
NC_017770.1\|WP_014680553.1\|2689323_2690199_-\|DUF4349-domain-containing-protein	gnl\|CDD\|379526	pfam14257, DUF4349, Domain of unknown function (DUF4349). This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important.	3.0306e-09
NC_017770.1\|WP_042479691.1\|2670378_2671506_-\|glycosyltransferase	gnl\|CDD\|133035	cd04192, GT_2_like_e, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	2.42232e-73
NC_017770.1\|WP_014680536.1\|2666469_2667819_-\|ammonium-transporter	gnl\|CDD\|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	1.29867e-149
NC_017770.1\|WP_014680539.1\|2669782_2670388_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236608	PRK09652, PRK09652, RNA polymerase sigma factor RpoE; Provisional.	3.05551e-47
NC_017770.1\|WP_014680552.1\|2686090_2689018_-\|TonB-dependent-receptor	gnl\|CDD\|372685	pfam13715, CarbopepD_reg_2, CarboxypepD_reg-like domain. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.	6.09365e-21
NC_017770.1\|WP_014680544.1\|2675415_2676321_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	5.26311e-13
NC_017770.1\|WP_014680548.1\|2680978_2682535_-\|TSUP-family-transporter	gnl\|CDD\|224562	COG1648, CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism].	2.31159e-38
NC_017770.1\|WP_014680542.1\|2672926_2674213_+\|transcriptional-regulator	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	3.41127e-07
NC_017770.1\|WP_014680535.1\|2665712_2666204_+\|histidine-phosphatase-family-protein	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	4.11923e-42
NC_017770.1\|WP_014680543.1\|2674313_2675429_+\|YjgP/YjgQ-family-permease	gnl\|CDD\|367632	pfam03739, YjgP_YjgQ, Predicted permease YjgP/YjgQ family. Members of this family are predicted integral membrane proteins of unknown function. They are about 350 amino acids long and contain about 6 transmembrane regions. They are predicted to be permeases although there is no verification of this.	1.45666e-54
NC_017770.1\|WP_014680554.1\|2690264_2691437_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181244	PRK08133, PRK08133, O-succinylhomoserine sulfhydrylase; Validated.	0
NC_017770.1\|WP_014680537.1\|2667913_2669008_-\|DNA-protecting-protein-DprA	gnl\|CDD\|376794	pfam02481, DNA_processg_A, DNA recombination-mediator protein A. The SMF family, of DNA processing chain A, dprA, are a group of bacterial proteins. In H. pylori, dprA is required for natural chromosomal and plasmid transformation. It has now been shown that DprA is found to bind cooperatively to single-stranded DNA (ssDNA) and to interact with RecA. In the process, DprA-RecA-ssDNA filaments are produced and these filaments catalyze the homology-dependent formation of joint molecules. While the E.coli SSB protein limits access of RecA to ssDNA, DprA alleviates this barrier. It is proposed that DprA is a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation.	2.01066e-101
NC_017770.1\|WP_014680549.1\|2682534_2683317_-\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	7.66557e-108

>NC_017770.1|WP_014680544.1|2675415_2676321_+|EamA-family-transporter
MLLNNNLFKLHFTVLIWGFTAILGKLISVSALSLVWYRVIIAAVALLIFIVLKKKSFKVKRSDLFQLVSVGILVTLHWIMFFHSIKISTVSVALVCLSSQTLFTGILEPIFMKTKISALDIITGILIVVGITFIFHFEGQYTWGIIYGLLASLLACIFNILNAKLVKREDPVVISFYELGGGWIGLSIFLLATGHFTNPANLALSNADIIYLLLLGIVCTAFAYVVGIAVMKELTAYTVALVTNLEPVYGVILALLIFKDKETMTMGFYIGAAIVIAAVVLYPFAKRRIDAYKEAKLGINV
>NC_017770.1|WP_014680543.1|2674313_2675429_+|YjgP/YjgQ-family-permease
MKSIINKFKKLLNITKLDEHIIKKFLGTFFFGLAIFIIIIVIFDISEKLDDFLKGSATFKQIVLDYYVNFVLFYVSVLSPVVIFLAVIFFTAKMANNTEIVPILSSGVSYFRFLYPYFITAAFLAVVSFIANAYIIPPSTRTKLDFEHTYIHTKYEYKGQNRHFKLDEHSYAYIQSYNIKDNSGYKFTLEKFKGDTLYYKLVANRIAWDTTKKEWKIENYSIRHNNGLKERMEGGDKLFMKLNLSTRDFEKQDDTRGSMTLPQLNRQIELEELRGTGNVSKYEMDRWRILTTPVSIFILVVMAVTLSSKKVRGGVGLPLGIGIGCSFAYIILMQFAEIFSTKGDLPTYIAAWVPHIIFGSLAIYLYKIAPK
>NC_017770.1|WP_014680542.1|2672926_2674213_+|transcriptional-regulator
MNTDFEFSHLRVAREQLGLTQKEAANASGISQRDISQLESGLKKFFPLEYILFLNINNVNLNILFSNNLNIQNLIQDRLGSIRSIDPVSIQFDYSIFKKAREKAGFTQKQASDRSGLSQRDISQLEAGLKKFIPFQFISYLILIKADLNEIFKYSTNIASTPVSSTINDQSLPKKPDFPVKNKAPENSLFDSTPAIGKEYSTHKASENSPESTIEISESKVQPVNILTTENIQVKEPEITPEIPVKAATVKSSIADTPPAIKKSKTANGIAVVNKHVVKGYIQQLDKRDFIGSLPELSIPGLEAGDFRAFEITGREMEPLFFEGDLVIGVKLDDFNEIKNNHLYIIVNDKRIIIRRIINCIKASAELILLTDNETVANEVQKIAAVKEVWEFNLKITASVDQLKNSFNELYFQLLKIQKDLDIIKSKL
>NC_017770.1|WP_014680541.1|2671744_2672875_+|tRNA-guanosine(34)-transglycosylase-Tgt
MKFDLVVTDNSSSARAGLMQTDHGTIETPIFMPVGTAGTVKAVHQRELKDDIEAQIILGNTYHLYLRPGLDTIQKAGGLHKFNGWEHPILTDSGGYQVYSLSDIRKIKEEGATFQSHIDGSKHLFTPENVMDIQRVIGADIIMAFDECTPYPCEYTYARKSMEMTHRWLKRCCDRFDSTEGLYGYNQTLFPIVQGSTFKDLRKQSAETIASFEREGNAIGGLSVGEPAPEMYEMTELVCNILPKAKPRYLMGVGTPMNILECIALGVDMFDCVMPTRNARNGMLFTQHGIINIKNEKWKNDFSPIDETSDLYADQVYTKAYLRHLLQSKEILGAQIATLHNLHFYLWLVKEARKHIIQGDFIQWKNKMVVDMGKRL
>NC_017770.1|WP_042479691.1|2670378_2671506_-|glycosyltransferase
MPIELTPLSITLLAVLTATFLINCAYLFLLYNKFAFKKQEESRLVKNEPVSIVICARNESANLEKNLPAILEQDYPEFEVIVVNDCSYDDSKDVLDAIAAKYKNLRIVQLEENDKYRHGKKFALTLGIKASKYDLLLLTDADCLPLSNLWVAKMVENYNNDTEIVLGYSPYSKQSGFLNKFIRFETFMTALNYLSFANAGKPYMGVGRNLSYRKDLFFRNKGFASHMHLPSGDDDLFVNAHATALNTRIEVSKEAAMLSEPKNTFSEFWQQKRRHMSVGKFYKPYHKCMLSIRTINALLFYGVFIAALILKINYEVVLTIFGLHLIFLTITYRKAMQKLQVQDLWFFSFLYDFVYNLYLVLMTLVKPSASKVRWK
>NC_017770.1|WP_014680539.1|2669782_2670388_-|sigma-70-family-RNA-polymerase-sigma-factor
MEINPNFSTNAVNDLNLVKQAIEGDQKAYGALMSRYRDSIYFMLLKMVNNKEDANDLTIETFAKAFRNLDKYQPTFAFSTWLFKIATNNCIDFLKKKRIATLSIDEPMDDDEESGKSFDVAGYTPTPEESIIRKQKAALLKNVVEGLPIRYKRLVILRYFEEYSYEEIAKELDLPLGTVKAQLFRARDLLFNTLRNTKNNI
>NC_017770.1|WP_042479688.1|2669117_2669741_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MDIILKYFPDLTTTQKEQFSKLFNLYAEWNEKINVVSRKDIEELYERHVLHSLGIAKVITFSAGTKILDIGTGGGFPGIPLAILFPEVSFHLVDSIGKKIKVVEEVAKGLGLTNVKTEHARAETINEKYDFVVSRAVTRLNNFCPWVKGKFLTESKNKLANGILYLKGGDLEEEIAEINKQVVMYPLGDFFKEDFFETKYVLHIPYV
>NC_017770.1|WP_014680537.1|2667913_2669008_-|DNA-protecting-protein-DprA
MSLLHQIALTQISGVGDILARNLISYCGSAEAVFTTKKISLLKIPGIGPKIVEAIKDRAVLLRAEKEIRFIERYGIETYFYADPQYPKRLKNCNDAPILIYFKGNCDLNRQRIINIVGSRKATEYGKEFTRRFVEGICQYNPIIVSGLAYGIDIAAHKEALRNNLSTIGVLAHGLDKIYPGTHRSIAEKMLETGGLLSEFPSETNADRENFPKRNRIVAGIADATIVIEAGESGGALITADIANSYNKDVFAVPGRVNDDYSIGCNNLIRDNKAQIITSAKDFVSFMLWEDKVKSNIKTISLFVELSKDEKFVFDIISAEKSIYIDDLIFKCGFSCSFVSKILLQLEFNSLIKQLPGKYYTVIS
>NC_017770.1|WP_014680536.1|2666469_2667819_-|ammonium-transporter
MAKKWHFFLFILLLISVVGLFAPVSGGNADNSAIVPADIAWILTASAMVFFMTPGLAFFYGGMVNKKNIISTMLSSFIALGVITVLWVVVGFSLAFGDDVGGFIGSPKTFFMFNHVFSGAPWKLAPTIPLMLFAIFQLKFAIITPAIVVGAVAERIKFAGYLLVMILFTLFVYTPLAHWTWHPEGFLFKMGVLDFAGGTVVHISAGCAALAGALVLKPRQDLLKGNSIFPANIPYVILGTGMLWFGWFGFNAGSALSASSLAVYAFATTAVASASAALSWIFFDAARGRKPSALGACIGAVVGLVAITPGAGFVAIGPSIFIGAVTSIISNLAVHWKSKTSIDDTLDVFPCHGLGGIIGMLLTGVFANKTINPAGADGLFYGGIDLFNKHLIALLIVVAYSFCVSWVIFKIANALIGLRVDEENENIGLDLSQHDETYSSRRNVYVPQS
>NC_017770.1|WP_014680535.1|2665712_2666204_+|histidine-phosphatase-family-protein
MKTLYLVRHAKSDKTITGISDFERPLNDRGLRDAPAMAKILAKKVNSPDLILSSPAVRALTTAQLFAEPLNYKAEKIQQCAEIYEAGVSTLLKTINEIDDRNNCVVMFGHNPGLTDLFNYLTDNDLINLPTSGIVKIDFDLDSWKLVSHGIGISTYIDYPKKV
>NC_017770.1|WP_014680545.1|2676966_2679816_+|hypothetical-protein
MRHLYRFKYLFISILTTLILTNASLAVFGQVFDNGQNPPSLKWKQIKTENYQVIFPSGFEKEAERTANVLEHLYNYVGRSLKTKSRKISIILQNQSVSSNGFVTLAPRHSEFYTTPPQDLEPNDWINSLAVHELRHVVQIDKTTSGINIPLIEEIQFAVFGGVFPIWFIEGDAVVTETVLSSSGRGRLPDWEKEFRANTLSGAKYSYSKYYFGSLKDNIPDYYRLGYFMSAKMRRDYGDSVYNALFTRAKNKFYIPWPFSNSLRHFTGYSTNQFFHQAVADLKNNWQKQLTDTKSITYNPINIRKNSVSTDYELPKALDSNEIICLKKGLADVASFVKIDKNGHEKKMLTIGPQLTPHFDLKNNTLVWDEIRYDPRFQYHTYSVICTYNLTSKTFKQLTKQSKYFSPALSSNGKTIAAVKISEANNFNIVLLNAETGEEIKTLENAANYFLQTPSFNANGDQLVYAVSSNLGRNIAVYDLTENREKLLLTWDFKQSLRPVFFGEKIIYHSSYNGIDNIYCFDTASKTNSQLTNAGIGVYNPSIDQYNQRILFNDFVKTGLNISAIPTGETTAINPEKTPSEFIQYYKPMIAREQGKSILDSFPSLSYKITPYKEASHLINFHSLSPYTQAGENDNYTAGISLKSNNLLNTMGITLGYSYDQSVKSGEYNASIAYKKFFPIFSLNYNNRKRTAVFDTLINNKETFREFSFRENKFDFSVSIPLSFYKSNYNYSVGFTSEISYISRYDINGGPKNLVKTINFPIDNTLYFYRTARRSARDINPKWGEQISIRYNSLPFDDQLDGSIFTVESSFFFPGLFKHHSFLASFNYQHNTGIYQSAVEIPEVSGAGNISRTSPLESTLLLRYRFPLFYPDWELSRFAYIKRFKGGFFADAENITSSGEFKSYGVELRADCNLLRYYLPNYDIGTKVIFFTDKGINSPVFQLIFNFTL
>NC_017770.1|WP_014680546.1|2679935_2680199_+|hypothetical-protein
MSFKTIFIIVVTILLTVIFMQNTSDVNVRILMWDVRVSFILLMASMAILCFLMGYFAAYRQRKITNTTLNAPNNEKNLSDEDKSYLQ
>NC_017770.1|WP_014680547.1|2680272_2680722_-|Rrf2-family-transcriptional-regulator
MLSKKTKYAIKALVALAKNETNNPMLIADIAKNEQLPKKFLEAILLELKHNGFVSSKKGAGGGYYMLKPAEEISLSAIIRIVDGPIAMLPCVSLNFYERCEECKDEITCGIRDVAKDVRDATLKILLETSIADIIKRESDLADHAKVEK
>NC_017770.1|WP_014680548.1|2680978_2682535_-|TSUP-family-transporter
MEELVELEKNDQPDSTVVHHPYLGHDRERNNLFPVFLKLEKLNTLIVGGGNVALEKLRAVISNSPDANIEVVAKEFNPEVKEFLDEYEISYEQKAFDATDLEDIDLVIVSVNDRNASAEIQKICTERHILVNVADTPDICDFYLSSVVQKGNLKLAISTNGKSPTIAKRVKEVLNDAFPYEIDDVLNNMEVIRKKLDGDFADKVRQLNDITSVLAVKTEPETKKRRKIVNLLTYIFSAVGLTILGFLAGKYATIDNYTVAEGWLSSHVTSEIFIFIIGGFIAQMIDGALGMAYGVSATTFLMSFGITPAAASASVHASEIFTTGVSGISHLKFGNVNTKLFKTLVIPGVLGAIMGAYILSSLQEYADYMKPLVATYTLILGIVIIRKVIKKRIVKKKLKRIGWLAGIGGFLDSVGGGGWGPIVTSTLIASGRHARYTIGSVNLTEFFVSFASSVTFILVLGLNHFQVIAGLIIGGSIAAPIAARLSSKLPVKTIMLAVGIIVILVSLRIIIMMVGKYI
>NC_017770.1|WP_014680549.1|2682534_2683317_-|uroporphyrinogen-III-C-methyltransferase
MQINNKHIQPKLTLVGAGPGDPDLLTIKGLKALADADVVLFDALANEELLKYASKQAELISVGKRAGKHSMKQEEINQLIVKKALQKGHVVRLKGGDPFIFGRGYEEIDYAEAFGVETAVVPGISSFYSVPELQKIPVTARGTNESFWVVTGTTASGELSKDIHHAAQSSATVIILMGMNKLAEIAHAFLVNGKSETPVAIIQNGSLPEEKAGYATVETMVDMAKDQNLANPAIIVIGEVVRLGRNSYLFEQLASLKKEN
>NC_017770.1|WP_014680550.1|2683344_2685444_-|HEPN-domain-containing-protein
MQSFRTELENPVVERDIIELERKIRLYRDGKIDEEKFRSLRLARGIYGQRQQGVQMVRIKLPYGKVTTQQLERICQVSDEYSRGNLHITTRQDIQIHYVSLDRTPELWAELERDDITLREACGNTVRNVTASATAGIDPKELFDVSPYAQAAFEYFLRNPVCQEMGRKVKIAFSSSESDTAYTFMHDLGFIPKIRVVNGKEERGFKVMLAGGLGSQPYLAEVAFEFLPINQIIPFSEAVLRVFDRYGERTKRHKARMKYLLQDVGLDGFLKLVEEERLALKYKVYEIDGTVTSELQPPAIIELPDFELSDWQKYDKWLTTNVFQQKQTGYFSVGLKIANGDIKTPVARQLIQIINELTADEIRLTNTQGILLKYVPAVHLPYLFQKLNEIGLAEIGFESTADITSCPGTDTCNLGISNSTDITRELEKVIYDEYPEFIYGNDISIKISGCINSCGQHAMAAIGFHGSSMKKDKLVLPALQVLIGGGVLGDGAGAVADKVIKVPSKRGPDVLRLLLNDYQENRNEGEYFLSYYQRQGKIYFYDLLNPLTDMDKITDDDFIDWGQTAPYVQAIGVGECAGVTIDLVATLLLESEEKTANAQEAFEKAEYADSIYYAYTSFINTAKAILTSEGIKTNTQSGIIKDFDLNFVQSEKVKLPVSFEELVYQINKDEPTADFAAYYLDQARGFTQLIKTYREAALA
>NC_017770.1|WP_014680551.1|2685727_2685871_-|hypothetical-protein
MKKIKEAVEAFKKGEEIVIEFKFTFDERHLLLLGGILTIVVVNLLTL
>NC_017770.1|WP_014680552.1|2686090_2689018_-|TonB-dependent-receptor
MKKSLLIAILLTFSLRLLAQDAILISGTIKDKDSHEALSGVSVRVKGTNSGTSTNNDGRFELKTRQKLPFVLQVFLVGFQSQEFEVKDINQSIALNLSSINIQANEVVVTASRVEESILKSPVAIEKLDIRAIKQSPAPTFYDALENVKGVQMTTSSLTFKVPNTRGFNIPNNFRFMQLVDGVDMQAATLGVPLGNAIGPTELDIASVEITPGAASALYGMNAINGMSNLLTKSPFVYQGLSVYSRNGINHIEGTGRDVSNLTETALRYAKAFNNKWAFKVNFSYMKGTDWLSDTRLDQNPNNLKTANPAYPALDGANNAVFDGWNKYGDDALAGSNTVSLTGLTIDGKPNQTLTVARTGYWEKDLVSPNVDNLKFDAALHYRITDNLEASYSYRFGKMDGVFQRGNKIQLDNVIVQNHKVELKGSNFLIRGYMSLEDTGDSFNVKPLADNMDLYSGGSGTAWAAKFKTALNTYGIDHGGALTSENLAAATQFARQAADASRVQPGTQAFQDLKNTIIGINNWDIKSATIPDAPETGGAALVQKSRLYNVEGQWDLSKQVKYFDLLIGADARIYDIIPDGNNFVDFSRPIEDRNKPLADGTFGNDVSYKKFGGFAQVTKTFFQEKLKLFGSVRMDYNPEFDPKLTPRIAAVYTLSEKHNFRVTFQQGYRFPALFEALSYVNNGRVKRVGSLPYINEGLGYLDNSYTQASVVNFNAAVKAAGNTDAAALANRDLLKVANLPDAGPERINSFEVGYKSILFNNKLVVDVDAYTNDYTGFLGQVQVYVPKGETVGSDAAVIAMVDRNRDPNPGTGGNAASKGQDRYRVYTNAKNTYRNYGSALGITYNFYKRYTVGGNVSFNKMKANETSDIFVTGFNTPEWSGNVSFGNREVVKNVGFSIIYKWQQSFLWESPLVTGTVDAIHTFDAQVSLAIPQAKASVKVGGTNLFNRNYIQYAGGPTLGGVYYVAITFDGLLNK
>NC_017770.1|WP_014680553.1|2689323_2690199_-|DUF4349-domain-containing-protein
MPNFKTQFWRISKWFGAVFILLFIFRLIYGYVAGGSVNYNNNYSEDFFSSIENLRKNYASEKILIKGANYQAVPSLSTNQKFEKTASIKTKSSEFEKDDKLIKGKTKSYSAVIQYEQNVGQQGNRQLHLVIGVNPAKFDSFYVDIQKIGLVKTKEITKVDKTNEYRQLNAKKVSIEKTLQSLNELKSRGGEITDFIALNDKILETEEKLQELGVELGNFDSENEFCTVKLSLYEGATEKKIGLFHRVKVSLEWTIKYFAIIVFISLVLSLTIFVLLLIADKLKVMNLLNNK
>NC_017770.1|WP_014680554.1|2690264_2691437_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MSNFETNAIRIQTERSGAKEHSAPIYLTSSYKFDDAEDMRALFANEREGNIYSRYSNPNTSELIEKMAILEGSETGWATSTGMAAIFTTFAAFLKSGDHVLSSRSVFGSTHQLLVNVFPKWGVTSTYADLDKPEEWENLIQPTTKMIFVETPSNPGIDIIDLEWLGKFAKKHNAILVVDNCFATPYLQQPIKYGADLSIHSATKYIDGQGRTLGGLILGSQKLIAEIEGFARHSGPAMSPFNAWMLSKSLETLAVRMDRHCDNALKVAEFLEANPEIELVKYPLLKSHPQYEIAKKQMRAGGGIVTFVVKGGYDRASKFMDALKMFSISANLGDTRSIATHPASSTHSKLTEAERQQVGINQGTVRVSIGLEHIDDILKDIKQALEVSKL

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Crispr_ID: NC_017770_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_7

2853670-2853755

Orphan

Consensus_repeat	Method
GTATAACTAAACAACTTTGCACTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_7

>merge|NC_017770|7|2853670-2853755|CRISPRCasFinder
GTATAACTAAACAACTTTGCACTGTCTAAAAGTCCCTCTTCTTAGAGGGATTTAGGATGAAGTATAACTGAAACAACTTTGCACTG

>NC_017770|7|6|2853670-2853755|CRISPRCasFinder
GTATAACTAAACAACTTTGCACTG	TCTAAAAGTCCCTCTTCTTAGAGGGATTTAGGATGAAG
TATAACTGAAACAACTTTGCACTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_042481197.1\|2856483_2857494_+\|DUF2157-domain-containing-protein	unknown	unknown	gnl\|CDD\|378311
NC_017770.1\|WP_042479713.1\|2859917_2860388_-\|type-I-restriction-enzyme-HsdR-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|372640
NC_017770.1\|WP_014680653.1\|2833257_2833701_-\|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|237999
NC_017770.1\|WP_014680650.1\|2830382_2830931_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680669.1\|2860850_2862152_+\|DUF4178-domain-containing-protein	unknown	unknown	gnl\|CDD\|379368
NC_017770.1\|WP_014680662.1\|2853821_2855765_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|143636
NC_017770.1\|WP_014680660.1\|2843638_2846923_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680668.1\|2860494_2860851_+\|S-adenosylmethionine-decarboxylase	unknown	unknown	gnl\|CDD\|376892
NC_017770.1\|WP_014680671.1\|2862338_2862563_+\|DUF350-domain-containing-protein	unknown	unknown	gnl\|CDD\|377187
NC_017770.1\|WP_014680659.1\|2840241_2843625_-\|RHS-repeat-associated-core-domain-containing-protein	unknown	unknown	gnl\|CDD\|274730
NC_017770.1\|WP_014680665.1\|2857490_2858681_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680658.1\|2839606_2840245_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680655.1\|2836913_2837810_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680670.1\|2862155_2862317_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680666.1\|2858754_2859780_-\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|273455
NC_017770.1\|WP_014680654.1\|2833707_2836440_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225743
NC_017770.1\|WP_014680652.1\|2832151_2833135_+\|NAD(P)H-quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|176180
NC_017770.1\|WP_014680661.1\|2847677_2853584_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173798
NC_017770.1\|WP_014680663.1\|2855768_2856344_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|214679
NC_017770.1\|WP_014680651.1\|2830955_2832143_+\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|274511

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_042481197.1\|2856483_2857494_+\|DUF2157-domain-containing-protein	gnl\|CDD\|378311	pfam09925, DUF2157, Predicted membrane protein (DUF2157). This domain, found in various hypothetical prokaryotic proteins, has no known function.	2.12833e-09
NC_017770.1\|WP_042479713.1\|2859917_2860388_-\|type-I-restriction-enzyme-HsdR-N-terminal-domain-containing-protein	gnl\|CDD\|372640	pfam13588, HSDR_N_2, Type I restriction enzyme R protein N-terminus (HSDR_N). This family consists of a number of N terminal regions found in type I restriction enzyme R (HSDR) proteins. Restriction and modification (R/M) systems are found in a wide variety of prokaryotes and are thought to protect the host bacterium from the uptake of foreign DNA. Type I restriction and modification systems are encoded by three genes: hsdR, hsdM, and hsdS. The three polypeptides, HsdR, HsdM, and HsdS, often assemble to give an enzyme (R2M2S1) that modifies hemimethylated DNA and restricts unmethylated DNA.	2.34814e-46
NC_017770.1\|WP_014680653.1\|2833257_2833701_-\|cyclic-nucleotide-binding-domain-containing-protein	gnl\|CDD\|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	1.1831e-21
NC_017770.1\|WP_014680669.1\|2860850_2862152_+\|DUF4178-domain-containing-protein	gnl\|CDD\|379368	pfam13785, DUF4178, Domain of unknown function (DUF4178).	1.11408e-13
NC_017770.1\|WP_014680662.1\|2853821_2855765_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	3.13336e-64
NC_017770.1\|WP_014680671.1\|2862338_2862563_+\|DUF350-domain-containing-protein	gnl\|CDD\|377187	pfam03994, DUF350, Domain of Unknown Function (DUF350). This domain occurs in a small set of of bacterial proteins. It has two transmembrane regions, and often occurs as tandem repeats. The are no conserved catalytic residues.	4.74695e-09
NC_017770.1\|WP_014680668.1\|2860494_2860851_+\|S-adenosylmethionine-decarboxylase	gnl\|CDD\|376892	pfam02675, AdoMet_dc, S-adenosylmethionine decarboxylase. This family contains several S-adenosylmethionine decarboxylase proteins from bacterial and archaebacterial species. S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the biosynthesis of spermidine and spermine, is first synthesized as a proenzyme, which is cleaved post translationally to form alpha and beta subunits. The alpha subunit contains a covalently bound pyruvoyl group derived from serine that is essential for activity.	1.04725e-21
NC_017770.1\|WP_014680659.1\|2840241_2843625_-\|RHS-repeat-associated-core-domain-containing-protein	gnl\|CDD\|274730	TIGR03696, tRNA_nuclease_WapA, RHS repeat-associated core domain. This model represents a conserved unique core sequence shared by large numbers of proteins. It is occasional in the Archaea Methanosarcina barkeri) but common in bacteria and eukaryotes. Most fall into two large classes. One class consists of long proteins in which two classes of repeats are abundant: an FG-GAP repeat (pfam01839) class, and an RHS repeat (pfam05593) or YD repeat (TIGR01643). This class includes secreted bacterial insecticidal toxins and intercellular signalling proteins such as the teneurins in animals. The other class consists of uncharacterized proteins shorter than 400 amino acids, where this core domain of about 75 amino acids tends to occur in the N-terminal half. Over twenty such proteins are found in Pseudomonas putida alone; little sequence similarity or repeat structure is found among these proteins outside the region modeled by this domain.	6.80083e-20
NC_017770.1\|WP_014680651.1\|2830955_2832143_+\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|274511	TIGR03300, assembly_YfgL, outer membrane assembly lipoprotein YfgL. Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking].	3.41604e-34
NC_017770.1\|WP_014680666.1\|2858754_2859780_-\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|273455	TIGR01128, DNA_polymerase_III_subunit_delta, DNA polymerase III, delta subunit. DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair].	8.75638e-43
NC_017770.1\|WP_014680654.1\|2833707_2836440_-\|hypothetical-protein	gnl\|CDD\|225743	COG3202, COG3202, ATP/ADP translocase [Energy production and conversion].	1.47229e-16
NC_017770.1\|WP_014680652.1\|2832151_2833135_+\|NAD(P)H-quinone-oxidoreductase	gnl\|CDD\|176180	cd05276, p53_inducible_oxidoreductase, PIG3 p53-inducible quinone oxidoreductase. PIG3 p53-inducible quinone oxidoreductase, a medium chain dehydrogenase/reductase family member, acts in the apoptotic pathway. PIG3 reduces ortho-quinones, but its apoptotic activity has been attributed to oxidative stress generation, since overexpression of PIG3 accumulates reactive oxygen species. PIG3 resembles the MDR family member quinone reductases, which catalyze the reduction of quinone to hydroxyquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NC_017770.1\|WP_014680661.1\|2847677_2853584_+\|S8-family-serine-peptidase	gnl\|CDD\|173798	cd05562, Peptidases_S53_like, Peptidase domain in the S53 family. Members of the peptidase S53 (sedolisin) family include endopeptidases and exopeptidases. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of Asn in subtilisin. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values. Characterized sedolisins include Kumamolisin, an extracellular calcium-dependent thermostable endopeptidase from Bacillus. The enzyme is synthesized with a 188 amino acid N-terminal preprotein region which is cleaved after the extraction into the extracellular space with low pH. One kumamolysin paralog, kumamolisin-As, is believed to be a collagenase. TPP1 is a serine protease that functions as a tripeptidyl exopeptidase as well as an endopeptidase. Less is known about PSCP from Pseudomonas which is thought to be an aspartic proteinase.	7.90726e-49
NC_017770.1\|WP_014680663.1\|2855768_2856344_-\|hypothetical-protein	gnl\|CDD\|214679	smart00471, HDc, Metal dependent phosphohydrolases with conserved 'HD' motif. Includes eukaryotic cyclic nucleotide phosphodiesterases (PDEc). This profile/HMM does not detect HD homologues in bacterial glycine aminoacyl-tRNA synthetases (beta subunit).	0.0013404

>NC_017770.1|WP_014680661.1|2847677_2853584_+|S8-family-serine-peptidase
MKNSPGGSILFNVGVVCIHFLLLIPFNLLGQQLEVKNFVVSGGFNQSSPQTYSATPSHAVVIGKGSSITGGSIGSDQLIKVLGKASIYSNLYSNGTIYLGDYTLVKGTIAAANSGKESGNVLKTGISQQLKGNIDVKGSVYIRSGSVLGTVTIPKGSSYYGPSPSGGKRYASPKLPILPQMPAITEFPKAGDKKITETQELTPNCYGPMELTGGKTITFSGTGTYVFSYIKNSGASPNKFIFDFKGDKTGVIKLYIHGDVDLNISNVDIINGGDASRIYAETHGTGNSCKLGNYAWTMTNYLANNRCSEWFGTIWAPYGGINIGSGSSSSSVKGALLSGTVVNIQCGVKITYCPFTECTPPKVNAGDDVEFTCPQTQVTLNGSCTTAPVQIKWTALNGGHIVTGENTLSPTVNSKGTYVLTATKDGCSASDTVIVTYKSCILPFYPPPVNGKDSSLIGAELTSLAVYGDSIQDPEQKIFVLSGDSVWVEVIAIEGQFQQLQSLLQTNEYGLTNLIDNGESQFIVSGRIPIDNLTKLNQLPQLINYCRPLFPPVGSAGITTSQGDIVMRTNYLRNGYELDGDSIKVGVLSDSYNTRPGNPAQTDVANGDLPGLNNSAYPVPVQVLMEFPFGRRVDEGRAMLQIIHDIAPKAQLAFRTGFISPGDLAQGILQLAATNCDVIVDDVTFITEPFFQDGVVSQAVDQVSAQGVAYFTSAGNFGNKSYQSVFVPATPPAGVSGQAHNFSGTGDVLQNISLQPGDYTIVLQWQDAFYSLGQTQTGTVNDLDIYLTDDNGSTLFGFNRNNLGGDPIEILPFTVISPTTTNILITRPSGTGSVSFKYIIFRGDGTINEYNSGNSTIVGQANAAGAFSIGAVRYTQTPAAGVNPPLIESFSSWGGTPINGQTRQKPDFTAPDGINTSINFDAPDLESDRIPNFFGTSAAAPHAAAVAALLKQARKKYYNQPYNNTELRELLSSTALDMNTPGFDFISGNGFIRADVAIQSLAAAKPELIRLLVPENVAPGNEPFTLTLRASYLSATTKVLFRDDTLATNYVNDSTATAPIPEFTGNPSIRAYTPSKSPTGRDGGVSNSITFFEIQKKNVKIKAENKIIRYGEQLPVFTSIITVDNKPLDSSGLTLTDLGLDSITYNTPATSTSNVNNYIVIPQRIFDLNNPVDAGFTELYTYTFENGVLSIEKMPLTITARDTTLTYGEKIGDISYTYQLPDSINLDDSIDLLDSIYTFHHNQLATDVIGLVNGKAVTIVNGKAVPIVNGQAVTIVNGQAVTIVNGKAVPIVNGQAITIVNGKAVPIVNNLSESEVQSLSFLATEKTLQGARQITNKKLVNGSVITQTSNVVDITQESVLDFNVNSAQTSMLTSITAVSPRGLIDDESFANKQAVTIVNGKAVAIVNGIEITQVNGQAVTIVNGKAVTIVNGQAIPIVNSQEKNAVIIDSTEIGQGLTSPLKSLNMITGSSIGLNYIIPGSLQNDNFDITYEVGKLTILPAALSIKANDTSKAYGAALKLDSLAFTISSGILMFEDSVKSVTLTSNGASASAGAGQYPIVPSTAIGGANTDLNNYLINYENGTLTVGKGLLTVKANNVTKVYGDPNPPFTATFTGFLNGDTFETSQISGQPDFTTTADLLSDAGKYPITVSLGSLSSPNYDFTFINENCLLTITQAPLTVKALDETITQKDPFPEFKAEFITLKANESPKVKFTVYPYYKGNPGEYAIIPLLVDFYNAKNYTINYENGTLYVNPDCPQTKKLRIYLDCVEEVKGSTYKYIAHFSCINPNSETVYLDKGEDNVLTSSGSFDDTQLPVVFVSGTTRFSVPFDGKTLTWQIKTIESGKKTAVASNASATSARCTKVYNNTTAQQSSGADIFKNDVSAGESLSVFPNPAARNVTVKAINGTLTVSSSNCLLYDLYGQFYPVRITKKISDSEFELDVSDLRNGLYYILVKNTDGYKTGRIIKE
>NC_017770.1|WP_014680660.1|2843638_2846923_-|hypothetical-protein
MNKFFLVSLIVLIPYILRAQQPEESQVKLRQVTPPSPQASALGKYGDIPVGNFTGTADISIPIYSLKIKDFTLPVAISYHTGGIKVEETATNVGLGWALSYGGNISVSVNGLNDFESNGFCNVISDPLKRLPDQPFPSNNVYNWYADGGGDLYKFAVDAAEGTTDTEPDLHYYSIPGNSGKFYFDQYDQAHTIPMSALKIQHFDGKYQITDEKGIIYSFEDVDQSVYDNTCNVGTVTGNFLLTKILLPDNNWITFTYVNNQYSLLTAKPETRTKLAAGQYGPTILECSNMANTITIRERVITKIESSTGTTVQFNYGTDRLDLPGTKNLASIAVLYQGQTKETYEFRQSYFSGTESRLKLDKVICNTNQTYEFEYETSVSLPSRLSFSQDHWGYYNNKSNNTLLPLDTEYGFTTGADRSPDFNYAKMAILKKVIYPTKGYTILEYEPNDYVYSGVKNVDVEKYNNLYSVADQTVTKQFTLPAPAQVLSVRAFYNAVAMNPGDEIPMDAPCSISLSGPNGYFSSFQGGSLSQGELLTGLAAGTYTMDLTTTGSYPSGYFSITVVERTSTNVTENREIGGLRVKRKTDYDAITSNNKVTRYLYKDEKTGLSTGKINFQPQYTYLYTHANMKDVISFTNYWKQATSSIFPLGSIKGGSVAYTTVTVLNGENGENGKIVYNYSFFPPYNIQNSFPLVPTSNEDWHNGLLLNEKSYKYNSPNDFSLIGQTINYYSDKKEEDFWNAHYSAQSLKANEYLRGWAIRIIYKNPPGTSGLSFTPATFSFNDYHLESKWLRLDSTVTRQYYGTDSVSTSQLFEYGNPAHFLKTKQTVLASNKIKYSTEFKYPQDSFTGLSATAETARQQLVAKNNITALMESSRYVGATKLEQIRTSYKVFSSNLCLPETIEAQSGSAELEKRVQFNNYNTYGNLLNQSLTDGAKIGYQWSAANQSLLAECKNAAENEFYFESFEEDAAASIVKFHTGKKCNYNRNFTVSFTKPNTRSYLISWFEFDGSKWVYKEETYTGSKAFTTTQYVDDIRVYPFDAQMTSYTYDPLVGMTSATDVKGQTAFYEYDEFGRLKYIKDADGFILKDHTYNYKQ
>NC_017770.1|WP_014680659.1|2840241_2843625_-|RHS-repeat-associated-core-domain-containing-protein
MKKHFSSKGALSALLTFCSLGLYAQSSNQNYVQTRTPLVPVTTAAAQNALTYTQQQTSIQYYDGLGRPLQTVQKQATTNAKDIVQPFEYDAFGREVKKYLPYSNITGSQDGSYKTNALTAGQGVWAHYKLATQSIDTTSFPFAETMLEASPLNRATEQGAPGKAFRVLKNASGASTLLGNTVKTEYGTNTATEVKLWTVTASGATGTTNYAANQLYKTILMDENWRPADGLPGKVEEFKDKEGKVVLKRTFNKNPAGTTETLSTYYVYDDFGNLRYVLPPAVTVSSFIETDALFKDLMYGYHYDSRQRVVEKKIPGKDWEYLVYNKLDQLVLTQDGNQRAAKEWTYTKYDALGRITSTGKYVHATVVTQPQMVTAVNASTTLWESRPVGSDYTNAAFPTSGVAQVYTVNYYDDYSFPQASTYPPQTDTLNTRSDIVRGLLTGTKVNVLGSADFLWTVNYYDKEGRVIQQHNQNYVGGKDVINTKYSFVGQPLVVKRVHTNNKGTGTQTFLYWYQYDHMGRKTRVLHKVINGTVNAAAQPVILADYAYNELGQLTAKKLHSIDKGQSYAQVLDYQYTIRGWLKKINDPAQISATSADKADKFGMELKYDNSSTPQFNGNISNMLWRGTKFSAPMMEYAFSYDKLNRLLRAQSMQGGNYEERVDSYDVMGNILKLRRWNDNNLIDSLIYTYKVPNLSNQLDHVDEKSNAAIPYKSQGFKEVNDIQQVGEYSYDVNGNMLIDKNAGITTNILYNYLNLPQMVVKEGTAINYLYDASGRKLRKTVGTTVDDYVDGLQLQTVGTTTTIKFISTEEGRANWNGATSAYYYHYDLKDHLGNTRVTISEAGAVLQEDSYYAFGMQIPGKSFNPTNKYLYNGKELQAETGWYDYGARFYDPTLGRWSVVDPLAEKMRRHSPYNYCFDNPIRFIDPDGMSPTGGPGPVPNIGNPMYPVLEGVRQYMQAGLGLLDNLYTSVTLTGSHVISNVKVSLGLAEGTVTNTEKISNTTEARFNFKEFMQNVDNKPAGPLFKFSNETKITNETEYEVSGKINLVDTKATGTKSKDLQTSQTSQSSEVTVGKKKIGFFLSNENTATSSKVDIGIKSDFNLDLGGFSFSIGIKAGAKVYEEKTNTK
>NC_017770.1|WP_014680658.1|2839606_2840245_-|hypothetical-protein
MSCNKYLSLVTVGIMSLVSCNNSPNSQSGNVTDHTIKKGITLDSTKWKCKVISTDVICYPNNWKELNQDKFFFFSYLNNNDSETFFVVNRLNEKEIKMDVNGYLKEVYRQLTADTIELCEGYTLKELTFQNNRKAYYGEFFSKKHGRSFFTRSFFLTYNSFIYDITLKVNERDRVNYSDIFQNILYNIKSSNKHLFDEKDLLRNVRDIDLSN
>NC_017770.1|WP_014680655.1|2836913_2837810_-|hypothetical-protein
MKTLSLYLLALLALIVYGCQKDIPTEEDIKKENKISKTIYLPIQIDQIQFPGGRTIKYYLEYENDEGDLKKVTTVPRTYDHIFSYTNGKLSETQSSWDHYQSTLGDAFATYTYLNNKIVGSISKQWEASPKPGAVPDQNGHYQDSDLVWELVTNDVSSFTWNSNWIIKRKSTRDCYNYEYDEFNMLLSHMFDGYSPTYTDQHYFHNDKNHWMKDIKNQYFIAGSLPFGGVFQKDLTRMQIMNLLGGATVPTEYNYYFESKYNEDSYPIETTVSIGSGNESPVVSAKYLFTYKKVVLNN
>NC_017770.1|WP_014680654.1|2833707_2836440_-|hypothetical-protein
MKNRVLNALNIKASESAYIFDLLRVQIFIGLAISYVNIIAYTLFLQALSIQLLPYAYLTIAPFLLLLNVAYEKLEHRSSPLRQLKYIILFSLVILICLWLGLSWGHRQYFIFALMVWSVLFYMLNGYAYWGIVSLLFNIRESKRVFSIVGAGDIPAKLIGYLSAPILIAFFGLINLLWMSVISLLIGLWFFHVAIQKTNWEAIKRSNNADHQVIDLQQDKRKKGLMDSLFKNELIFAISILTILSYNVFNLIDFTFLSHVKLKYEDIGSLAAFIAAFFAVGRIIALVFKLMITSRVIERWGIVICLFITPVILFLFSLVFFAMDQQSEYILYVFGMMVLLTEVLRSAMQEPIFFILFQPLKEKVRLHGHLITKGYMLPPSLIMVGLSLIILNKMGIEVTILLTIKIVLINLVAWAAAIMYVKRAYLRTLHRSISKGIFNSDEVYLNDQKSIDILLNKIANGKKSEIIYALKLLGKANHPDIMNLLYQQLYKEDKEVKLYVLSEISKIKKPDIDLLKQLVAHESDSEIKQSLTSIICRNDKGYLEMLSEQIEHLEYAVRKVVIISLLNQDEFNHLFKAGNELNNLIQSTVPEERDLAIHIISELKNVRFTDAIEQLINDEDISVKRNAIMVACKLKIKSILPDILGMLSNSSGKYIALQGLLQYGDDLFDDIEPSVINNHTSELVGLAGKMKGMQSTNFLLMHLSTSPDWINKIVHALWRKEYRPSTSNESGLINHVLDDRFLSAKDKIDCFYAIQPFKNHVLVKNSLRSEIQNDLETCLRLCCLLYDKQEINRILELFETEDSSKLYNAMEMLEMVLPQRVIRELNMLFDHFIDPDDTRKIHKKQEINHLFDKIVFTNANEFTPWTKAVSIYSLWKNKDYDFIRKLSVNETPSQSYVMQETTTYVLNALT
>NC_017770.1|WP_014680653.1|2833257_2833701_-|cyclic-nucleotide-binding-domain-containing-protein
MLIIEKVLLLKNSEIFKNCRETDLMEIASICQEYLVDKGVRVFNKGDRGNCMYFIYSGKVLIHDEEHEIVTLSENEIFGELSLLDTESRSASVTTLTDCTFLKIEQETFYDVIATNSDILKGIMRTLCKRLREQDRITIEMKKVMSL
>NC_017770.1|WP_014680652.1|2832151_2833135_+|NAD(P)H-quinone-oxidoreductase
MKASIITQPGGPEVLVLQEREKPSIKATEVLVKVIAAGVNRPDVAQRAGRYPAPPGAPADIPGLELAGIIVETGAEVTTLKIGDEVCALVAGGAYAEFCTVPAELCLPVPKGLTMVEAASLPETFFTVWSNVFDRGSLKSEESLLLHGGSSGIGTTAIQMAKALGNTVYATAGSDEKCSYCESLGADKCINYKTEDFEEVIKTITNNKGVDVILDMVGGSYIPKNLNILADDGRLVFINAMKGFKTEVDFLKVMQKRLTITGSTLRPRPNSFKAQIAQNLIKHVWPLIEQGQIKPTIYKTFPLEKANEAHALMESNEHMGKIVLKVS
>NC_017770.1|WP_014680651.1|2830955_2832143_+|PQQ-binding-like-beta-propeller-repeat-protein
MKKQIILTILSVLISNFITAQPQPFWKFKTAGKIAGSPCVSNNKIIIGSEDGFLYAIDKTNGQQLWKYQGDAPIKSTPATVNGTVFFNNANGNMYAIDATSGKMLWKQQMPGEKIVDFWDYYLSSPVLHDNLVIVGSGNGAVYAFDQKTGKQVWTFKTDGVVHADPLIQNNTVYVGSFDGNFYSLNATSGQLLWKFKTVGDMFFPKGEIQNGASFFNNTVYFGSRDFNIYALNAEKGTGAWNMKERGSWVIATPAIADSLAFFGTSDTHTFYCLGALYSEVKWKIPLNMRVYGKAAFYENLVLFGCFNGKLYAADKKTGTIKWEYQTEASKQNWLTIFDETGHIKKGFELYGDDVHIANTEKIIMNLGSILSSPIVEQNMVYFGSTDGYVYALKM
>NC_017770.1|WP_014680650.1|2830382_2830931_+|hypothetical-protein
MIHQFDIQAFIKNCIGLISISFICSALSSIKGGIIFTPLIYGFYLCFTYPEKLRYKNVSLILLPLLFLALFLTGGGMFFVIDLHVKSPDKDPLLFAIIGIWTSQVLLVLIWALLKIKLTIGGLIQMAILVLPPYLLKLHPVETADNSIFLFYFLWQSGFSIGLSTILSLATNSKQSLNSNHS
>NC_017770.1|WP_014680662.1|2853821_2855765_+|tetratricopeptide-repeat-protein
MKFNKIIICALLISVPYYGISQTENTKNLADTVQVNNYLQQSKERFNDNPAKAISLAIEAKKLAEKIKFPKGRAYALKNIGIAYYFQGKYVEALDNYTQSLNQFKEIKDNVGIANLYNNIGVIYYDQGDDAKALENYLQSLKYAELSKDKLRILSALNNVGGVYNIKDATYDKALHYYLLALPLCEELNRTEELGAISVNIGSIYFDKNDDTKALHYFNKALKAYGNSEGSLNAYNAMGKLYKREKKYDQALENHQKALALAENLNIKISIIQSLIGMGNVYLDKGDFKTALYFFNRAKIPALEIQAKHEIKDIYQVLSKVYAKTNNYEKAFEYQSLYANIKDTLYNIESDKKLGNLQFDFDLQKKQGEINLLTKDKALQQLALERQKIAKNSLIAVLGLICIIGLILYRDYRNKIRLNKLLDQQKVEIENLLANILPEEVAKELKEKGQATPRYYESVSVLFTDFKSFTAIAETLSPQQVVAELSECFTMFDTIIERNNLEKIKTIGDSYMCAGGIPTVNSTHPINIMKAAFEILGFMNEINNRRKLNGATPWEIRIGIHTGPLVAGVVGKKKYAYDIWGSTVNIASRMESNGEPGQINISAAHYELIKHEYECEYRGKILAKNAGEIDMYFVKQKVTVRNIEVSA
>NC_017770.1|WP_014680663.1|2855768_2856344_-|hypothetical-protein
MYDQVFEELRVLVFDKLSKLDEHLTYHCKEHTTDVLTQSEQIAKREGVTDKHQLHLLKVAALYHDSGFLNTYKDHETYSCSLFLMDADRFGFSKEDKEQITSLIMATKIPQQPHNLLEQIICDADLDYLGRDDFYKIGETLRKEFLHYSIVNSDEEWETLQIKFLQNHHYHTISSQQLREPIKHQYLLQLG
>NC_017770.1|WP_042481197.1|2856483_2857494_+|DUF2157-domain-containing-protein
MNNQLAEKLHAEGLINDASFSKINERNSNPLFSVHWELKSLLYIGVMLLSSGLGVLVYKNIDTIGHQAILAFIAMVCGTGFWYCFKKKAPFSTEKVNSPNSFFDYVLLLSCLTFLTFVGYLQYVYTVFGTNYGMATFIPMVVLFFVAYYFDHLGVLSLAITNLALWMGLSITPTRFLQDNDFDSERIIYTALLLGVILLFAAYFSERQNIKKHFKFTYQNFGLHITFIALLAGYFYYYLSVYEVELSYYQPFAFAWLLILGALAYLYYIDSVKSKSFYFLLIITLYSYIAISCLAVRVFMAMDDIGAVYMAFMYFIGSAVGIVLFLINVNKKLKSA
>NC_017770.1|WP_014680665.1|2857490_2858681_+|hypothetical-protein
MIVYNKTWLDNLKIQQEAEQANDNGYISAEELKNIQQKYPVGFYTPNLFIRIGLFILTCIIILFSCGLIGLILADAIDSETGFAVLAIIGGISIYAILERVMIKDKHHYRSGVDDALLYCSAILISSGVYILLYKMMNDNLDVYPEIPAFLLCVFAALLTLRFADSLMCTIAYLSFFFCCYSIIIKSSSWGIAIAPFFLMLISALVYLWAAKTDKKQKAMNYSICLIILQIASLTTLYLSGNYFIVRELGSSISGLPEEAPLPLGWFFWLWTIAIPFVYIGWGIKKKDVVLIRMGLLLIAIAAFTFRNYYHVMPIEVTLTLCGIAAIGIAYSIIKYLTPSKNGFTYEDSDEKHFMDKLNVEAVVIAQTFGPAQTQPSGETGFGGGDFGGGGAGDKF
>NC_017770.1|WP_014680666.1|2858754_2859780_-|DNA-polymerase-III-subunit-delta
MTASEIIKELKAKKYRPIYFLHGEEEYYIDLIGNYIENNVLSEAEKGFNQTVLYGKDTDIITILNNAKRYPMMSEHQVVIVKEAQNIKFGKDKGDKDQDPFAAYIENPLRSTVLVFCYKHGKIDGRLKMFKNIEKNGILFESKKLYDNQVPGWITEHVQEQGVRISPQATALLAEYLGNDLLKISNELEKLMINISKGTEIGTKEIEENIGISKEYNVFEFQNALGKRDVLKANRIVNYFAANKKENPAVVVFATLAGYFSKIFVYHCLKDKSKPAVASALGVNPFFVGDYEIAARNYPQGKTMQIISLLRQYDLKSKGVGSTGNTEEGELMKELVWKILH
>NC_017770.1|WP_042479713.1|2859917_2860388_-|type-I-restriction-enzyme-HsdR-N-terminal-domain-containing-protein
MPQLPALNLPPFPFQLKEEGGKLYIFDEIRKKHLILTPEEWVRQHFIQYLIKERNYPKGLINIEGGLKVNELAKRSDILLFNTQGEKYLLVECKADTVKLTQKAFDQLAQYNITHKARIIVLTNGLEHYCCEIDHENKTYQFLQEVPVYTTETLKR
>NC_017770.1|WP_014680668.1|2860494_2860851_+|S-adenosylmethionine-decarboxylase
MTSYKPGLHIIAEFSSAKNNLLSDHTFCKPFFDELINRFELSKVGEVYHNFENGGFTAVICLTESHLSIHTWPEFNLATFDVFLSNFKQVNNHKVKAIYAETLDFFGGSEMNKHEIAR
>NC_017770.1|WP_014680669.1|2860850_2862152_+|DUF4178-domain-containing-protein
MGDLLNHKHLTSTGFVNCPDCGTQFKVFDYTNSNHFGCANCHTFFTFRMQIRSFNIKDFEAKPAIPIGSIGTFEGNSYTLAGFMVKKEKGNNYKWREYLLINAEKGYAFLSEFDGHWNFIAGTNHYPDLTSVKGNNYSVTYQDKEYKLFNKYEPQLLYAAGEFDWDVVNEHINARELIAPPCMLVRENQGKSGDWFLATYNTPSEVAEAFKIKRNVLPTRFGVGANQPAAFERQFNGLMMVTTFTVILMFAILWAFNFNKPEKEVFHENYIPQRDSAGWGGGSYKTINTGSFKVDGPTALNVELRSDVSNEWMEVPITLINDKTGQFYDFSKAIEFYHGYEDGESWTEGSRDANAVLSNIPSGYYHLSIEPASDGRGDEGLEVVITQNTILWSNFFIFLLLIAVYPIFQFVRRAYFDRQRWSNSDYSPYDRDN
>NC_017770.1|WP_014680670.1|2862155_2862317_+|hypothetical-protein
MLQNLKELKYYILLLMIALGGYTWLTLNGIKLLGDDNQSKENRSGYTRSYYHK
>NC_017770.1|WP_014680671.1|2862338_2862563_+|DUF350-domain-containing-protein
MTLSELINVKYVVASILYSGLGILILLVSFWIIEKITPENLWKEILEKRNMALALMASAYMIALAIIIASAIHG

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Crispr_ID: NC_017770_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_8

3012031-3012142

Orphan

Consensus_repeat	Method
CAAGAGCTTCATTTCTCTGTTGACTGAAGTCAACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_8

>merge|NC_017770|8|3012031-3012142|CRISPRCasFinder
CAAGAGCTTCATTTCTCTGTTGACTGAAGTCAACGACAATGAAGTCTTTTTTTATCGATCGCTATTATCAATCATGACAAGAGCTTCATTTCTCTGTTGATTGAAGTCAACG

>NC_017770|8|7|3012031-3012142|CRISPRCasFinder
CAAGAGCTTCATTTCTCTGTTGACTGAAGTCAACG	ACAATGAAGTCTTTTTTTATCGATCGCTATTATCAATCATGA
CAAGAGCTTCATTTCTCTGTTGATTGAAGTCAACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014680785.1\|3006408_3006900_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_017770.1\|WP_157604567.1\|3005898_3006048_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680801.1\|3023631_3024192_+\|DUF3347-domain-containing-protein	unknown	unknown	gnl\|CDD\|378730
NC_017770.1\|WP_014680796.1\|3017023_3018925_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226220
NC_017770.1\|WP_014680790.1\|3010721_3011378_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319898
NC_017770.1\|WP_014680787.1\|3007952_3008330_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680786.1\|3006874_3007915_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067
NC_017770.1\|WP_014680792.1\|3012411_3014649_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NC_017770.1\|WP_042479758.1\|3015259_3015646_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680784.1\|3002829_3005037_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|350795
NC_017770.1\|WP_086021113.1\|3011379_3011949_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017770.1\|WP_014680795.1\|3015762_3017037_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226220
NC_017770.1\|WP_157604566.1\|3005443_3005581_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_042481237.1\|3002325_3002733_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|226134
NC_017770.1\|WP_014680800.1\|3022937_3023600_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_169313289.1\|3018965_3020282_+\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NC_017770.1\|WP_014680789.1\|3008642_3010532_-\|M1-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341067
NC_017770.1\|WP_014680799.1\|3021629_3022907_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|379862
NC_017770.1\|WP_014680793.1\|3014896_3015103_+\|copper-chaperone	unknown	unknown	gnl\|CDD\|215516
NC_017770.1\|WP_014680798.1\|3020259_3021633_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|379862

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014680785.1\|3006408_3006900_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	3.56493e-37
NC_017770.1\|WP_014680784.1\|3002829_3005037_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|350795	cd18037, DEXSc_Pif1_like, DEAD-box helicase domain of Pif1. Pif1 and other members of this family are RecD-like helicases involved in maintaining genome stability through unwinding double-stranded DNAs (dsDNAs), DNA/RNA hybrids, and G quadruplex (G4) structures. The members of Pif1 helicase subfamily studied so far all appear to contribute to telomere maintenance. Pif1 is a member of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	8.55804e-54
NC_017770.1\|WP_014680796.1\|3017023_3018925_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
NC_017770.1\|WP_014680790.1\|3010721_3011378_+\|VOC-family-protein	gnl\|CDD\|319898	cd06587, VOC, vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.	1.78181e-09
NC_017770.1\|WP_014680786.1\|3006874_3007915_+\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	1.85031e-65
NC_017770.1\|WP_014680793.1\|3014896_3015103_+\|copper-chaperone	gnl\|CDD\|215516	PLN02957, PLN02957, copper, zinc superoxide dismutase.	3.29811e-05
NC_017770.1\|WP_014680801.1\|3023631_3024192_+\|DUF3347-domain-containing-protein	gnl\|CDD\|378730	pfam11827, DUF3347, Protein of unknown function (DUF3347). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 169 to 570 amino acids in length.	2.57976e-55
NC_017770.1\|WP_014680799.1\|3021629_3022907_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|379862	pfam16576, HlyD_D23, Barrel-sandwich domain of CusB or HlyD membrane-fusion. HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.	2.12815e-59
NC_017770.1\|WP_086021113.1\|3011379_3011949_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.10393e-20
NC_017770.1\|WP_014680795.1\|3015762_3017037_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|226220	COG3696, COG3696, Putative silver efflux pump [Inorganic ion transport and metabolism].	0
NC_017770.1\|WP_014680792.1\|3012411_3014649_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_017770.1\|WP_042481237.1\|3002325_3002733_-\|VOC-family-protein	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.06799e-59
NC_017770.1\|WP_169313289.1\|3018965_3020282_+\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	7.92081e-12
NC_017770.1\|WP_014680789.1\|3008642_3010532_-\|M1-family-metallopeptidase	gnl\|CDD\|341067	cd09604, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains bacterial M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	4.26973e-119
NC_017770.1\|WP_014680798.1\|3020259_3021633_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|379862	pfam16576, HlyD_D23, Barrel-sandwich domain of CusB or HlyD membrane-fusion. HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.	1.03205e-53

>NC_017770.1|WP_086021113.1|3011379_3011949_+|AraC-family-transcriptional-regulator
MMILHVKNMVCNRCIKVVNDELNNLGLNPKEVKLGEIEFEEELQPQALQKIKSALEENGFELLEDKQTQLIERIKALIIELVQDEKGINLKTNLSEYLSSALHTDYSALSNLFSSFEGITIEKYLILQRIEKAKELLLYDELTLSEISYRLNYSSVAHLSSQFKKVTGLTPSEFKKMLAPKRLPLDSVI
>NC_017770.1|WP_014680790.1|3010721_3011378_+|VOC-family-protein
MNIKEVHILTNDLKKTAAFYSDLLGFTIIEKDLQHVSFSVNQTILRFSLTTSIINPVYHLAFDIPNNTFDEAFTWLAPKAEILNVTPESKIADFVRWNAKSFYFFDSNGNILEFITRYDNHVETTAAFNASAVLSVSEVGIVTDNVNDTSNKLVAKYDLQFFSKQPPLPDFTVLGDNNGLFIIVQKDRAWYPTDKKSSVFYTKVIFEDKGQLQEFELT
>NC_017770.1|WP_014680789.1|3008642_3010532_-|M1-family-metallopeptidase
MKLIKVCLFSLGTFFSFYSYSQELYKSVNVKAAIEKGTRSENGKPGSNYWQNKADYKMKINFDPQTKVLSGEETITYYNNSPDSLNNVAIRLYSDLYKKGVERNVTIDPKDENDGVTIEAVRIGNEEINEFNNTRKIVRSGTNMYLTPAKAIQAKSVQTIYIKWHYTVNTGSQMRTGAVDETSYFIAYSFPRVSVYDDVNGWDYWSYKGTQEFYNDFGDFDVEITASKNYVVWATGELQNATDNLSATVLKRLKSAAITNKNVHVIDSTDYKKNNVFAANPTGSWKFKAKYVPDFAFALSDHYLWDASSVLADSVTKRRVMVHTAYNKKHHDYFEVQDIANKSVELMSHHYPAIPFPYPQITIVDGTDQMEYPMMVNDNPTQTRKDAVQLVSHEVFHTYFPFYMGINETAYAWMDEGWATIGESILSPMMGEAEDDGIYSKTRYENISGTDADMPLITNTKYYDERAYITNSYGKGALCYHTLQNMLGDKLFFKALHQYMDNWNGKHPIPYDFFNSFNAATGKDLNWFWKAWFFGWDYPDLAIKNVSTANAESSVIIENKGGLPVPIYLTIVLSDGKKIEKHYTAEVWAKGNKEFVISDKYASGIASVEVGNIYTPDKFKENNVWKAVK
>NC_017770.1|WP_014680787.1|3007952_3008330_-|hypothetical-protein
MKTINLVIERQGGQFWGRTIIEDDLLTDYADTKEELKTKIHNLAIDFHGQEYQHVRFDVEYDLEAFFDEFKELKTIEIAHITGLDPTLVHQYALGEKTATAIQVQKIEDAVHDLGRRLQAVKLNG
>NC_017770.1|WP_014680786.1|3006874_3007915_+|EamA-family-transporter
MKTIDNNYEPSKALVIAAFAAIYIIWGSTYLGIMVAIQSIPPMLMGGLRFLVAGLLLLSWCIYKKEKFPPRSTIIKSGITGLILLLWGNGAVIWAEQYIPSNITAIVVAGAPLWMTLLDKREWKNSFTNMAIVAGLLVGFAGVILLVSSGGKEAHFSLSDPKQFMGLLVLLSGSIAWVAGSLFTKYSPTEGSTLMKVSIQMLVASVAFLLVAFSRGEFHTYDWSQTTTKSWVALGYLITFGSLIGYLSYVWLLSVKTPAQVGTYAYVNPSVAVLLGWLIIDEPITMIQIFALVIILFGVMLVNKGNQVRAKKNLAKVQEPTIMEKIEHERSFVTADKGMLCTEDKA
>NC_017770.1|WP_014680785.1|3006408_3006900_+|Lrp/AsnC-family-transcriptional-regulator
MFELDDIDLKILALKQDNACMSNADLAKSLGMAPSAMLERVRKLEKRGIIQSYTTRINPLALNQRLLAFVFIKTSSAPCDCNQDEAIVQLPGIQEVHHIAGDDCYLIKIRTENSQSLVKWMREELGRVSGILSTRTTIVLETLKETTQLTIPNLQNENDRQQL
>NC_017770.1|WP_157604567.1|3005898_3006048_+|hypothetical-protein
MKSVISITTRNLIKAQPEKVPIQLIVFSDTEPVGMSLVKLFLGYNGIYL
>NC_017770.1|WP_157604566.1|3005443_3005581_-|hypothetical-protein
MFYGVGCSLRTDFEKLKAQYRTILSFSITSTIIYSNYWYAPMGYL
>NC_017770.1|WP_014680784.1|3002829_3005037_-|helix-turn-helix-domain-containing-protein
MYDHQNSTFKLAVQFVNQTNRHLFLTGKAGTGKTTFLRYIHDHTSKKTIIVAPTGVAAINAGGVTIHSFFQLPFGAFLPVNKPFWGSENGQFHTIHSFLKNAKVSRERRELIQEMELLIIDEVSMVRADLLDTIDAALRHIRKNPQPFGGVQVLYIGDLFQLPPVVKDGEWATLRQYYKTPFFFDARVIEQTAPLYLELTKIYRQKDHVFIDILNNIRNSIVLQSDLDLLHKYYKPDFKAPREENYITLTSHTAKADTINRTELEQLSGEIRTFKAEIIGDFGEKSFPAEEALELKENAQIMFIRNDKGDNRRYYNGKLATVKSIAAESIVVQFADGTDIELEKESWKNIKYQFNNDDDSFEEKIIGEFKQYPVRLAWAITIHKSQGLTFEKAVIDAGASFASGQVYVALSRLTNMEGMVLLSPIKPGSITADRSVLEFCKSGVEERLLEEQFKEDRKQFVHSLLVKTFEWAKVTDRLEYHYNDFARGLVPDKSEAASLAEKWYRISVEQKNTADKFIAQLNNLIAEAQSAGYERLKERIDKAEQYFNTSLDEIISTLGDHINVTRKKKRTTKYVKTLKELEVFLIRKAELIKAAQRIAHGLASGEETEELIEAAQVKHPVKVEPEPETPEKKKKGDSHRISLELYKNGKAITEIASEREMAESTIEGHLASFIATGEITIEELVAAEKLPVILNAINEVGSNSLGVLKEKLGADFSYADIKAVLAYHKTRSSTT
>NC_017770.1|WP_042481237.1|3002325_3002733_-|VOC-family-protein
MATQIFVNLPIKNLDATVEFFTKLGFTFNAQFTDEKATCMIVGENIFFMLLVEKFFQTFTKKEICDAKKSTEAILTISVETKAEVDEMINKAVAAGGAITGDPQDHGWMYARGFYDLDGHHWEIMFADMSQLPQS
>NC_017770.1|WP_014680792.1|3012411_3014649_+|copper-translocating-P-type-ATPase
MTAITHTSGTNKLLKQIFPVDGMTCASCAVSVESMLRNTPGVAKADVNFAASSVTVEYDNHKTNPDLLKKTVQSIGYDILITEKASEEQAEQQELKYEQLKKRTIWAGIFTFPVFVIGMFFMHWQPGNWIMMVLTGIVLFVFGKQFFINAYKQAKIGAANMDTLVALSSGVAYIFSAINTLFPHLLHRIGQHTPVYYESAAVVVTFILVGRLLEERSKSKTSSAIKKLMGLQAKTVTIDDNGTEREISIDDVHPDQIIIVKPGEKIPVDGTLISGSSFINESTITGESLPVAKTIDDKVFAGTINQQGSFKFKAEKVGKETLLGQIIRHVEETMGSKAPVQKLVDKISGIFVPIVMLIAITSFAAWMFFGQKDPWYHAITALVAVLAIACPCALGLATPTALMVGVGKGAENGILVKDAESLEIARKVNAIVLDKTGTITRGMPEVTDFIWLKKDAEQYASFVLSLEQRSEHPLGKSIVEYLKAKDVSSIDPDDIENISGKGLKGLFNDKTVLAGNKALLDQFSIAITAEVLNQAQQLQQQAKTVSYIAVDKEVVALVAIADQIKEGSKAAISELQALGVDVYMLTGDNMETAQAVAKQTGIQHVKAGLLPTDKAAFVKQLQSEGKIVAMSGDGINDSPALAQADLSIAMGKGADIAMDVAKITLISSDLRQIPKALHLSTFTVRTIRQNLFWAFIYNLVGIPLAAGLFYPIFGWQLDPMFAGAAMALSSVSVVTNSLRLQRKRI
>NC_017770.1|WP_014680793.1|3014896_3015103_+|copper-chaperone
MNTLKFKTNIKCSGCIATVTPKLNALTAEENWQVDLTSPDKVLSVEGDVTPEQVEKALAEVGYKAEIL
>NC_017770.1|WP_042479758.1|3015259_3015646_+|hypothetical-protein
MTKRVLILCFTFLFLLLNAGIPVYAHYCGKKVTSTDFQEQKKCCCNKPEEKPMKDCCKDEAKLVKVEDNFLKIHHEFKAPLLSVHFAISFVITSLGILTDANEQSVYLNTSPPDLPVARFILLQNFRI
>NC_017770.1|WP_014680795.1|3015762_3017037_+|efflux-RND-transporter-permease-subunit
MISAIISWSMRNRFIVIIATIGLTIFGWFSMQDTPIDAIPDLSENQVIVYTEWMGRSPQIMEDQVTFPLVTNLQGMPKVKDVRAASMFGMSFIYVIFEDNVDIYWARTRVMERLNSAQRSLPEGVTPTLGPDGTGVGHIFWYTLDAPGYDLGELRALQDWYVKFALQNVPGVSEVASYGGFQKQYQVTIDPNKINYYKLTLMDVLNTIKNNNNDVGGRVFEMNGTGYIVRGLGYVKNISDIENMTIATRNTIPVRVKDIGTVQMGGDARLGIIEENGNGEVVGGIVVMRYGENADAVINRVKEKMKEVEKGLPKGVKFKVAYDRSDLIEAAINSLKNTMIEEIILVCIVIIIFLFHFSSSLVVMINIPISILLSFIAIKYFGITSNIMSLSGIAIAIGVIVDDGIVMVENAYRHLTEEGGDDHA
>NC_017770.1|WP_014680796.1|3017023_3018925_+|efflux-RND-transporter-permease-subunit
MIMRDVRKLSTEERISIIEKSARQVGKPVVYSTIIIIVSFLPVFLLTGQEGKLFHPLAWTKTLVMLSSVVLAITFVPVMMTFFLKGKMRPESQNPISNFFNRIYEPILKWCLEWKKTVLGINILALGISVPMIMGLGREFMPPLDEGSLLFMPVTLPDVSNSEAKRILQVQDKIIMSVPEVKNVLGKAGRANTATDNAPMSMIESIILLKPQSEWRKGKTKDDIIAELNAKLQIPGVTNGWTQPIINRINMLSTGIRTDVGVKVYGQNLDTIYTISREIEKALKDVEGIADLYPEQVTGGKFLDIKIKEAELGRYGLSVNDVNMIVESALGGMNITNTVEGRERYSVSVRLAQDFRSSIEDIKRTLIQTANGPIPLSSVADVAIKNGPAMINSENAMLRGTVLFNVRGRDLGNTVNDAIQKLNETLTLPKGYYIDWSGQWENQLRATKTLSIIVPIVLVIIFFILYMTYNQMKEAIITMLSVPFALIGGVFLVYFWGMNISVAVAVGFIALFGVAVETGMLMVVYLDEAMQKMVKEKGASVSISELRHYVIEGSAKRLRPKLMTVSVTLFGLIPILWSHGTGIDLMLPIALPMIGGMITSTIHVLLVTPIIFEMTKEHELKKHGKVEVLNVKH
>NC_017770.1|WP_169313289.1|3018965_3020282_+|TolC-family-protein
MQCHPEKRRICKFPGIFVKDASYLSMTSIWLFIILTGFALTANAQSVVPLRAVLDSITANNPGLQKFEYSTKANIEMGNMSKAWDAPTIAVGLDEFPYPSEMQMDGAARKMFMVNVDQMLPNFANQKAKSEYYKSFRNQNQNDYETLKNKLFAQAKAAYYTELISVKRLKVIEEQSKMLELLIKIAEARLQYSQSDLPTIYNAKAKISSLESMKIKEESMIKQSRSTLNYLMGRPLTDDFKVDTSLALNRYTEQISQYDTSFVMHNRSDIQRMSNDIASMRLNQKVAQTMAKPMFGFGFKNMRMQDGTYMYSAMASMKLPIVPWASKGYKSEVKAIDYEIKAMERERTNMVRETSSMIKNTMLDLQAQYREVDVYEKRILPDYKKTFDVNLNAFGENKGDIFRTLMAWDDLLMKRMDYLNVLDQTYKMEVMYEEAIQK
>NC_017770.1|WP_014680798.1|3020259_3021633_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKLFRNRLGNHQNAKAQRNNLSVIATLRTSSFRWLFLVIVALGLFSCNSKKSTVSEAAAVYTCPMHPQVVQDHPGTCPMCGMDLEKKVEASDVSDKEKQELAALAQEVNETVVGNFKTIYPRKRSATDTIRLKGYLGLDDRAKNKVSSRVSGRIERLYIKYENQTVKKGQKLFEIYSPELLAAQRDLLYVIKNDDQQLVSGLKNRLINLGMTSAEVNQVIKTGKPIQYISIYSAYNGISHQITSGTSGAAATSGGAAMGMGGGSAGATPATSSAPLSSIREGMYVNKGQTLFELMGHGQAWALFSAYDKDLPFIKEGDNVLITIPSEKGHQMSGKVDFIQPYYGENEQTATIRVYLPNHHELKIGTLIEGEISGKNAADGYFVPKTAVYNLGKTTIVWVADKADKVFKARKITIGAAAGDWVEVKTGLNASEKVAVNAAYLVDSDSFIQVEEGGTK
>NC_017770.1|WP_014680799.1|3021629_3022907_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MSNYKISRKDARTQSNLNLGSLATWRAISFSLLFFLVSCTQEKPKEHDHAAETKNKAAEVYSCSMHPNVRSDKPGNCPICGMPLTKIAGSEAKHEERTLHLAPVQLVTANIKTDSIRMGNLNANITLTAKTNYNRQAQDVISARVAGRIERMFVRNPGEQISAGQKLYELYSEELQSTQQEYLISLKQQKAFEAVSVDMSRAINSLERKMELWGMSKSQIHQIATSGKVSPTITVYSKQSGTVTEILKNEGEYVAEGDAVLNLAKLNEIWIEAEVFDNELAVLAKKPKIEVELEAFPGKLYPASVVFDNPHMRGVSNVNLLTLKINNNLDLKPGMLASVHLSTGENNEITVPKSAIAFGEHMNHAWIRRPDGSFERREVKLGKENKRSVQLISGVHIGEVIVTSGVYLLDSEYTLKFGTAMGHQH
>NC_017770.1|WP_014680800.1|3022937_3023600_+|hypothetical-protein
MFNTFFRHILTGLFLLSLFSLPAQAHNGEDHVKDTSKKEEVIKNDHQHQGELHAKHEHSPAAASEAAAPGEFPHLHPLFVHIPISFICITALVVLVNLLLRKREFDWLILGFIAIGVISAYIAGKWFHPHTRGISEQAKHLLTEHDFWADWTIYLGFVGLIIQIVYLFVLKGKRWVSAIAYLFILGSAYAIFHAGHYGAALVHIEGVGPQGKYLEQHHNH
>NC_017770.1|WP_014680801.1|3023631_3024192_+|DUF3347-domain-containing-protein
MKTKFYIAVALVAGVLAACDGQAKKAENHEGHDHSSHDGHSHEATVQNTSPTGPSFNSDALNNVYGHYIHLKNNLVASNEAESKTAAAALKTAIADLKDAEVLKAAEQTAAATNLEGIRASFNDLSKQIERVIKSTGVKSGEVYVEFCPMANNDKGGFWLSNSSEIQNPYYGDQMMKCGSVEETLK

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Crispr_ID: NC_017770_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_9

3050539-3050637

Orphan

Consensus_repeat	Method
CAGTTCAATAAGATATCCCTATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_9

>merge|NC_017770|9|3050539-3050637|CRISPRCasFinder
CAGTTCAATAAGATATCCCTATCTATAGGTAATAATAGTAATTAGCCGTTAGCTATTGGAAATTAACTGAAGTTATCAATTCAATAAGATATCCCTATC

>NC_017770|9|8|3050539-3050637|CRISPRCasFinder
CAGTTCAATAAGATATCCCTATC	TATAGGTAATAATAGTAATTAGCCGTTAGCTATTGGAAATTAACTGAAGTTAT
CAATTCAATAAGATATCCCTATC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014680834.1\|3054503_3055286_+\|pyruvate-formate-lyase-activating-protein	unknown	unknown	gnl\|CDD\|131546
NC_017770.1\|WP_014680833.1\|3052186_3054421_+\|formate-C-acetyltransferase	unknown	unknown	gnl\|CDD\|153087
NC_017770.1\|WP_014680828.1\|3046602_3048081_-\|RNA-polymerase-factor-sigma-54	unknown	unknown	gnl\|CDD\|235648
NC_017770.1\|WP_014680830.1\|3048925_3049405_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381284
NC_017770.1\|WP_014680832.1\|3050901_3052092_+\|OFA-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340911
NC_017770.1\|WP_014680827.1\|3045849_3046554_+\|aquaporin-family-protein	unknown	unknown	gnl\|CDD\|223653
NC_017770.1\|WP_014680825.1\|3044606_3045050_-\|DUF2147-domain-containing-protein	unknown	unknown	gnl\|CDD\|378304
NC_017770.1\|WP_014680841.1\|3059836_3060340_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680838.1\|3057037_3057262_+\|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl\|CDD\|376620
NC_017770.1\|WP_014680826.1\|3045139_3045694_+\|glutathione-peroxidase	unknown	unknown	gnl\|CDD\|238207
NC_017770.1\|WP_014680835.1\|3055289_3056177_-\|ChaN-family-lipoprotein	unknown	unknown	gnl\|CDD\|350609
NC_017770.1\|WP_014680824.1\|3043676_3044531_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|172341
NC_017770.1\|WP_042479764.1\|3042316_3042757_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680823.1\|3042856_3043558_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014680840.1\|3059150_3059834_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl\|CDD\|274750
NC_017770.1\|WP_014680836.1\|3056386_3056545_+\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NC_017770.1\|WP_014680839.1\|3057370_3059026_+\|S41-family-peptidase	unknown	unknown	gnl\|CDD\|223864
NC_017770.1\|WP_014680837.1\|3056633_3057038_+\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234989
NC_017770.1\|WP_014680831.1\|3049547_3050477_+\|DUF3078-domain-containing-protein	unknown	unknown	gnl\|CDD\|378621
NC_017770.1\|WP_014680829.1\|3048438_3048852_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014680834.1\|3054503_3055286_+\|pyruvate-formate-lyase-activating-protein	gnl\|CDD\|131546	TIGR02493, PFLA, pyruvate formate-lyase 1-activating enzyme. An iron-sulfur protein with a radical-SAM domain (pfam04055). A single glycine residue in EC 2.3.1.54, formate C-acetyltransferase (formate-pyruvate lyase), is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter. The reaction requires Fe2+. The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5-yl radical, which then abstracts a hydrogen radical from the glycine residue. [Energy metabolism, Anaerobic, Protein fate, Protein modification and repair].	8.52578e-107
NC_017770.1\|WP_014680828.1\|3046602_3048081_-\|RNA-polymerase-factor-sigma-54	gnl\|CDD\|235648	PRK05932, PRK05932, RNA polymerase factor sigma-54; Reviewed.	8.03156e-140
NC_017770.1\|WP_014680833.1\|3052186_3054421_+\|formate-C-acetyltransferase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NC_017770.1\|WP_014680830.1\|3048925_3049405_+\|hypothetical-protein	gnl\|CDD\|381284	cd14775, TrHb2_O-like, Truncated hemoglobins, group 2 (O); uncharacterized subgroup. The M- and S families exhibit the canonical secondary structure of hemoglobins, a 3-over-3 alpha-helical sandwich structure (3/3 Mb-fold), built by eight alpha-helical segments. Truncated hemoglobins (TrHbs, 2/2Hb, or 2/2 globins) or the T family globins adopt a 2-on-2 alpha-helical sandwich structure, resulting from extensive and complex modifications of the canonical 3-on-3 alpha-helical sandwich that are distributed throughout the whole protein molecule. TrHbs are classified into three main groups based on their structural properties and named after Mycobacterium sp. genes glbN, glbO, and glbP: TrHb1s (N), TrHb2s (O) and TrHb3s (P).	8.56282e-63
NC_017770.1\|WP_014680832.1\|3050901_3052092_+\|OFA-family-MFS-transporter	gnl\|CDD\|340911	cd17353, MFS_OFA_like, Oxalate:formate antiporter (OFA) and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Oxalobacter formigenes oxalate:formate antiporter (OFA or OxlT) and similar proteins. O. formigenes, a commensal found in the gut of animals and humans, plays an important role in clearing dietary oxalate from the intestinal tract, which is carried out by OFA/OxlT, an anion transporter that facilitates the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation. This exchange generates an electrochemical proton gradient and is the source of energy for ATP synthesis in this cell. The OFA-like subfamily belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.62332e-87
NC_017770.1\|WP_014680827.1\|3045849_3046554_+\|aquaporin-family-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	7.66283e-76
NC_017770.1\|WP_014680825.1\|3044606_3045050_-\|DUF2147-domain-containing-protein	gnl\|CDD\|378304	pfam09917, DUF2147, Uncharacterized protein conserved in bacteria (DUF2147). This domain, found in various hypothetical prokaryotic proteins, has no known function.	1.72936e-45
NC_017770.1\|WP_014680838.1\|3057037_3057262_+\|membrane-protein-insertion-efficiency-factor-YidD	gnl\|CDD\|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	6.79866e-42
NC_017770.1\|WP_014680826.1\|3045139_3045694_+\|glutathione-peroxidase	gnl\|CDD\|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	2.9357e-70
NC_017770.1\|WP_014680824.1\|3043676_3044531_-\|hypothetical-protein	gnl\|CDD\|172341	PRK13808, PRK13808, adenylate kinase; Provisional.	0.00422083
NC_017770.1\|WP_014680835.1\|3055289_3056177_-\|ChaN-family-lipoprotein	gnl\|CDD\|350609	cd14727, ChanN-like, ChaN is an iron-regulated, heme-binding protein. This family represents a domain found in ChaN, a heme-binding/iron-regulated lipoprotein from Campylobacter jejuni. ChaN, possibly involved in the uptake of heme-iron, contains a pair of cofacial heme groups situated between two ChaN monomers. A single tyrosine residue contacts the heme-bound iron atom while the heme-binding regions of each monomer also have contacts to the heme in the complementary monomer. ChaN presumably associates with an outer membrane-associated receptor, ChaR. Campylobacter jejuni is an important cause of food-borne illness, and is dependent on iron uptake from the host. ChaN like proteins are related to the Tiki/TraB like family of proteases. Proteins containing this domain also include protein reticulata-related from Arabidopsis which may play a role in leaf development.	2.67543e-75
NC_017770.1\|WP_014680840.1\|3059150_3059834_+\|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl\|CDD\|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	2.09686e-62
NC_017770.1\|WP_014680836.1\|3056386_3056545_+\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	6.1693e-10
NC_017770.1\|WP_014680839.1\|3057370_3059026_+\|S41-family-peptidase	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	1.82196e-95
NC_017770.1\|WP_014680837.1\|3056633_3057038_+\|ribonuclease-P-protein-component	gnl\|CDD\|234989	PRK01903, rnpA, ribonuclease P protein component.	3.61887e-26
NC_017770.1\|WP_014680831.1\|3049547_3050477_+\|DUF3078-domain-containing-protein	gnl\|CDD\|378621	pfam11276, DUF3078, Protein of unknown function (DUF3078). This bacterial family of proteins has no known function.	3.19472e-23
NC_017770.1\|WP_014680829.1\|3048438_3048852_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	6.74924e-62

>NC_017770.1|WP_014680831.1|3049547_3050477_+|DUF3078-domain-containing-protein
MRKPTVLLTIVLLFCLKAFSQDVDSTRKWTLGGTNTFQFSQASFSNWAAGGQNSLTFITAFKAFAKRNTPKNDWETIFDAAFGTQRLEDNDYRKTEDRFELNSKYGIKASDKLYATFLMSLRSQFLVGYKFAADGSSTKVSNFLAPGYLTASFGLDYKPYQGLSLYISPFGSRTTMVFDQDLADQGAYGVKPADTANGQILKHGSNIFQQVGLNASFRYDGKLFENVKLTTKLDLFSTYENLNAMDVYWEALFDCKINRFLTANLSTGLIYDQKVMIKKPEYVNGVLTDVSRPRVQFKEIISLGVKFSY
>NC_017770.1|WP_014680830.1|3048925_3049405_+|hypothetical-protein
MKSIPTLYEWVGGNDALEKLTEVFYDKVLKDDLLYPVFKNMSGNHSKHVAHFIAEVFGGPSLYTQGDKGSHATMVAHHLGKMLDEQKRQRWIQLLLQSADEIELANDPEFRSALVAYLEWGSRIAVINSTTTENPVNENEPMPSWGWGETKGPYIPDTD
>NC_017770.1|WP_014680829.1|3048438_3048852_+|large-conductance-mechanosensitive-channel-protein-MscL
MSFIKEFKEFAMRGNVIDLAVGVVIGGAFGKIVTSLVDDIIMPPIGYLIGGFDFKAFKITLKEAVVDAAGKVTPEVAINLGNFIQVLIQFVIIAFAIFIAIKAINTLKKKEEAAAAPTPPTEALLAEIRDLLKNRPL
>NC_017770.1|WP_014680828.1|3046602_3048081_-|RNA-polymerase-factor-sigma-54
MLKQNLQQKLLQKLSPQQLQFIKLLQIPTVMLDTRIKEELEENPALEDVSLISHNEEKDEYNFDDDNSDDYNESENESSSEEFSIEDYLQDDGEKDYATSLAYDGEDEDDKKELPYAESRSFFELLQFQLSLVELEDRNFLIAQQIIGSLDDDGYLRRPIISLTDDLAFSQNIDATEEEIEAMLKIIQSFDPPGIGARDLQECLLIQLRKKDQDNRIVHLATEIVENYLDEFTKKHYEKLERSLNISSEELKMAVNEILKLNPKPGDSNADGNSKQMQVIPDFHIANNDGVLVLTLNSRNAPELRVSRDYKEMFQTYDKQTNKDKKLKEAVQFVKQKLDSAKWFIDAIKQRQQTLIKTMNAIMHYQYDYFLEGDERKLKPMILKDIADQIGMDISTVSRVANSKYVQTEFGTFLLKSFFSEAIQTESGEEVSNREVKKILEDCIGNEDKRRPLADEKLAEILKDKGYNIARRTVAKYREQMNIPVARLRKEL
>NC_017770.1|WP_014680827.1|3045849_3046554_+|aquaporin-family-protein
MTAYLYEFIGTAILILLGNGVVANVLLAKSKGQNGGWIVITFGWAIAVFVAVIVSSKNSGAHLNPAVSIGLAMAGKFSWQLVPAYVLAQISGAFAGAVLVWLTYKKHYDETTEAGLIEATFCTAPAIPHTINNLFTEIVGTFVLIFTILYLASPQVGIGSVDALPVSLVVLGIGLSLGGPTGYAINPARDFGPRLAHAFLPINHKGMNNWNYCWIPIIGPIIGSILAALVFKGL
>NC_017770.1|WP_014680826.1|3045139_3045694_+|glutathione-peroxidase
MQTLFIIMTLFFGACNSQVVSNDGNTPPKTSFYDLKFTSIDEEPINFSKYKGKKLLIVNTASECGYTPQYADLEKLNEEYGDKIVILGFPANNFGGQEPGSNTEIKGFCKKNYGVTFQMFEKSSVKGDDKNVVYQWLTDKNKNGWNDQEPTWNFCKYLINENGELVKFFPSKIKPTDQQILSLL
>NC_017770.1|WP_014680825.1|3044606_3045050_-|DUF2147-domain-containing-protein
MKKLLLFTLVACFFSVASFAQSGADAINGTWFNKDKDAKIQIFKKGNEYFGKIIWLKNPKNEQGQDKKDDKNPDDNLKKRTINGLEILKSFKYDTSDEKWSEGTIYDPKSGKTYDCKLTLKDKNNLNVRGFIGVSIIGRTDVWTRTN
>NC_017770.1|WP_014680824.1|3043676_3044531_-|hypothetical-protein
MVFEQGVAMKVKGLYSVLPIFLLVMLLGVGPAFAQVKKDTKSTSTGKTTSTASQKTGVAKKPAVQDSAKKAVKPVDSLSKAKGKTAVNQKTAAAAGKKTPDGKTVVDPKKTPVKPVVVKLAPDLIKPNSVGILKLGMRIDTIKKLFPKDRVYRVYVYDAKDKYEQYQVTAADKSSQFLLINPECDGDSICSIRQIVAKNVYFKTERDIKVGMMLDDLILAYGFLESRWEEENLIVRNREGIDFVMDTSDIPKRWYRKMNLDRLPLPTRIIGIMITVGSPQTARN
>NC_017770.1|WP_014680823.1|3042856_3043558_-|hypothetical-protein
METVNRIFFEGNPYPKGHTIKKFVWSGRLDPSQGIYFDFHLETENYYAEDNSTDVSDPESDWTSKGVWSNYHKCTLSSTNWDNGGVLIATENTLLDFDSLTSTVLTADKLPEGVNILPDDWSDDELAFHIYLLGHDTCAEHEINFADRNTDGSFNIQWNGRIALTYGGDYEFNHSFKTLVNNVKFSGIYLPSDITTVEAVEAFKKFVKNPDHFELEDLNPKSFKREYKLVLKD
>NC_017770.1|WP_042479764.1|3042316_3042757_+|hypothetical-protein
MKKLLILTTLLSSSFMVKAQHVSDMIKSPVWDIIGTLKINTVNQSKQVAVFPPQLKSLDNKNVTLQGYIIPTEEGIKHKRFLLSTLPINQCYYCGKNGIPIMIEVEMGEAIDFTYKPVMIAGILKLNYANAAENIPISLEKASQLN
>NC_017770.1|WP_014680832.1|3050901_3052092_+|OFA-family-MFS-transporter
MLKRNKWLIALAGMMLQLSIGSVYAYSVWIKPINLSNGWDAHQLKLAFSLAICFLGLTAAFMGKFVQKIGPQKAGLLGAIFWGAGLLGSGFAASQGSLPLFYFFYGIISGIGLGFGYITPVSVVVKWFTEKPGFASGLVIMSFAAGSIIASKIIPSLAATYGVPNAFYILGITYFILMLLASIYLTLPETTVNSSSNTTTVKLSELLSDLRFYSLWLMLFFNTTCGIALIAIAAPMAKDIIHINDAAAITFVATIGLFNGLGRLIWSSISDKIGRWNTFMAFFLIGAICFLVLSNTQTSFIFQVTVFIIISCYGGAFATMPAFVKDIYGTDKVGSVLGYVLTAWSAAAFAGPWLITVTTNYSMIFYLFAGLLILIAAISLLVKSKLQNKIAVLVIS
>NC_017770.1|WP_014680833.1|3052186_3054421_+|formate-C-acetyltransferase
MKADVEKVPFTSGEWNTSLNVYNFVVKNITSYTGDSSFLVGPSIKTTYLWNICQDTLRKERENDGCLGIDTETISTMTAFKPGFINKENEVIVGLQTDELLKRAMKPFGGIKLVESAVKERGLKVSDRVIDVFNYAKNHNEKVFDAYDQEIRTFRSKHILTGLPDNYARGRIIGDFRRVALYGIDQLIKFKWADYDKVSGEMTEHKVRLREEISLQISALKDMLLMASEYGYDISRPAETAQEAVQWVYFAYLAAVKEQDGAAMSLGNVSSFLDIFIERDLEAGLMTESEAQELIDQFVMKLRMVRHLRPAAYDEIFGGDPTWVTECIGGQLHDGRTKVTKTSYRFLQTLYNLGASPEPNLTVLWSEQLPESFKRFCAQVSIDTSSIQYENDDLMRPNRGSDDYGIACCVSHQEIGKSIQHFGARANLPKALLIALNGGREEHGGTQVLKDIPQIDEGVLDYDIVLDLFKRSMKELARVYSKAMYIIHYMHDKYYYERAQMSLIDTDPHIDIAYGAAGISIIADSLSAIKYAKVTAIRNVKGLTTGFNIEGDFPKYGNDDDRVDTIAQEITSYFIGELRKHKAYKNATPTLSLLTITSNVMYGTNTGATPDGRDNGESFAPGANPMHGRDCSGAIASLNSVAKLNYNDAQDGISNTFSMIPKSLGDTRGEQINNLVNTMEGYFKQMAHHLNVNVLNRETLMDAYEHPENYPQLTIRVSGYAVNFVRLSRAHQLEVIARTFHENM
>NC_017770.1|WP_014680834.1|3054503_3055286_+|pyruvate-formate-lyase-activating-protein
MYFPLQDIEAAKLNKDDPEHLRIHSLETFGTHDGPGIRMVVFVQGCQFRCVYCQNPDTLDVTGGTLVTIEELVKRAVRQRNYFGKEGGVTVSGGEPLLQRSKLTDFFLLLHEEGINTCLDTNGRLNNKEVHELLAYTDLLLLDVKHINNEIHHRLTGLTNKNTLGLAEYRESTGKRMWLRYVLVPGWTDQPEHLEEWGQHFANYKTVERVEIIPFHQLGAHKWELLNMNYPLKDTLPPTAESKKQALDIFQKYFKNVILK
>NC_017770.1|WP_014680835.1|3055289_3056177_-|ChaN-family-lipoprotein
MNYSLLIKIAVVCFCVQLLSAVSRAQTKGLPYKIYSSAENKQLTIDELAAQLIKAQVIVFGEEHNDSVGHVLQLAVLEKLFLQSKGKVALSLEMFERDIQPVINEYLTNMIREKNFMNDARPWKNYADYKPLIEFAKKNTIPVIAANAPSRYVNRVTRLGLASLSELNDQSKTFLPPLPIDTLSGAYYHKFLKTLGGHNMPGMQIYQSQNLWDASMADVITSFIVKNKEFKVLQLNGRFHSDECLGVCYRLKKAGLKVTTISCFSDDSFKNPDFTKFSQLADFIIVTDPSVKRTF
>NC_017770.1|WP_014680836.1|3056386_3056545_+|50S-ribosomal-protein-L34
MKRTYQPSRRKRSNKHGFRERMASANGRRVLASRRAKGRKRLTVSDEKRHKA
>NC_017770.1|WP_014680837.1|3056633_3057038_+|ribonuclease-P-protein-component
MNTFKKEERLCSKKLIGELLQNGSSFLVYPFRVVWVNQPADLPRPFPAQILISVSKKRFKRANKRNYIKRLVREAYRVNKQEFLYHSLEEQNMAVAFMCSYIGNEIFTYTELEKKLKLLLERLKKEVVKSLPKV
>NC_017770.1|WP_014680838.1|3057037_3057262_+|membrane-protein-insertion-efficiency-factor-YidD
MLNRVLNYIFIALIRFYQYAISPLLGQNCRFTPTCSQYGVDAIKKHGPWKGGWLTIKRISRCHPWGGHGHDPVP
>NC_017770.1|WP_014680839.1|3057370_3059026_+|S41-family-peptidase
MFKRYKKTLLVLAVAASSLGTMAFVDDFFEISKNLDIFSALYREVNTNYVDEVEPAKLMRTGIDAMLKSLDPYTNFYSESEIEDVRFMTTGQYGGIGATIAQRKGEIVVNEPYEGSPAQTAGLRAGDIIVAIDGKSTKGKNSGDVTTFLKGQPNTPVVLTLRRPGENADFQKTLTRQEIKIKNVPYFSMVTDNIGYIKLTGFTQNAGNEVKDALAELKKNGGLKAVILDLRGNPGGLLNEAVNVTNVFVDRGQLIVTTKGKVADNNRSYKTLNTPIDLAIPVAVLTNSQSASASEIVSGAIQDLDRGVVVGQRTFGKGLVQNTRPLAFNTQMKITVAKYYIPSGRCIQALDYTHRNPDGSVGKIPDSLIREFKTTNGRKVYDGGGVTPDFVTDQNSLSSIAISLLSKSLLFDYATNYRNKNATIAPAKTFTLSDADYNDFVKYLSDKDYDYVTASEKTLEEYKNAAIKEKYFDAIKPDYEKLKNSLKHDKQSDLVKFKDEISGLLESEIATRYYYQRGKIESTLKRDKDIKKAVEVLTNTNQYNTALAVKN
>NC_017770.1|WP_014680840.1|3059150_3059834_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MALILSLETATACCSVALSENDSIISYKEETSPNIHAGSLTLFIEEVMKTPGKQLTDVDAIAVSMGPGSYTGLRIGVSTAKGLCYSLDKPLIAVNTLKAMAKGFQLTINSNKTTLLCPMIDARRMEVFTAIFDQQLDEVIPTSAVIIDASSFSDILNDKQITFFGNGAEKCSSILTSTHALFDNGSYNSARFIAPLAFEKFLRNEFENVAYFEPFYLKDFVSTQPKK
>NC_017770.1|WP_014680841.1|3059836_3060340_-|hypothetical-protein
MKSHLIFLFAGILFISCVKDKKKETISKSSNSAGATSMVKHEEMLKKDSMVSIKTRDGKSSNILKEKLKGYYFDQETENVLADTIHELVIHYLTKVDKDWIASQVNDPHFYYTAESQERGGTEYYAIRLTHELDGMQTTIQWIYIDLKNRKIFEYDLPNDELISFLK

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Crispr_ID: NC_017770_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017770_10

4912564-4912679

Orphan

Consensus_repeat	Method
GGTTTCTTGTATAATTGAAATAAAGGTTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017770_10

>merge|NC_017770|10|4912564-4912679|CRISPRCasFinder
GGTTTCTTGTATAATTGAAATAAAGGTTGAATAAAAAATATGCAAAGGCTCCTGGTTCATGACTGTCGACTCAAGACTGTTAACACGGTTTCTTGTAAAATTGAAATAAAGGTTGA

>NC_017770|10|9|4912564-4912679|CRISPRCasFinder
GGTTTCTTGTATAATTGAAATAAAGGTTGA	ATAAAAAATATGCAAAGGCTCCTGGTTCATGACTGTCGACTCAAGACTGTTAACAC
GGTTTCTTGTAAAATTGAAATAAAGGTTGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017770.1\|WP_014682435.1\|4910344_4910602_+\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|171099
NC_017770.1\|WP_052308720.1\|4904324_4904870_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|236773
NC_017770.1\|WP_042480314.1\|4919842_4920799_-\|stage-II-sporulation-protein-M	unknown	unknown	gnl\|CDD\|376676
NC_017770.1\|WP_014682431.1\|4906405_4908031_+\|pyruvate-dehydrogenase-complex-dihydrolipoamide-acetyltransferase	unknown	unknown	gnl\|CDD\|237001
NC_017770.1\|WP_014682430.1\|4905258_4906254_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl\|CDD\|274473
NC_017770.1\|WP_042480306.1\|4908954_4909428_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014682443.1\|4918259_4918985_-\|DUF4129-domain-containing-protein	unknown	unknown	unknown
NC_017770.1\|WP_014682444.1\|4918968_4919859_-\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014682442.1\|4917081_4918257_-\|DUF4350-domain-containing-protein	unknown	unknown	gnl\|CDD\|379527
NC_017770.1\|WP_014682436.1\|4910592_4910850_+\|Txe/YoeB-family-addiction-module-toxin	unknown	unknown	gnl\|CDD\|284238
NC_017770.1\|WP_014682447.1\|4921719_4922082_+\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|319869
NC_017770.1\|WP_157604780.1\|4913281_4914652_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234586
NC_017770.1\|WP_014682437.1\|4910899_4912444_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143448
NC_017770.1\|WP_014682434.1\|4909522_4910266_+\|SLATT-domain-containing-protein	unknown	unknown	gnl\|CDD\|335700
NC_017770.1\|WP_157604618.1\|4903920_4904079_+\|hypothetical-protein	unknown	unknown	unknown
NC_017770.1\|WP_014682438.1\|4912817_4913270_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NC_017770.1\|WP_014682432.1\|4908233_4908953_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|226651
NC_017770.1\|WP_014682441.1\|4916053_4917028_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NC_017770.1\|WP_014682446.1\|4920899_4921625_+\|RDD-family-protein	unknown	unknown	gnl\|CDD\|377640
NC_017770.1\|WP_014682440.1\|4914722_4916054_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635

Protein	Function_ID	Function_description	E-value
NC_017770.1\|WP_014682435.1\|4910344_4910602_+\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|171099	PRK11409, PRK11409, YoeB-YefM toxin-antitoxin system antitoxin YefM.	1.58144e-10
NC_017770.1\|WP_052308720.1\|4904324_4904870_-\|C40-family-peptidase	gnl\|CDD\|236773	PRK10838, spr, bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase.	5.64464e-27
NC_017770.1\|WP_014682447.1\|4921719_4922082_+\|four-helix-bundle-protein	gnl\|CDD\|319869	cd16377, 23S_rRNA_IVP_like, 23S rRNA-intervening sequence protein and similar proteins. A family of functionally uncharacterized bacterial proteins, some of which are encoded by an atypically large intervening sequence present within some 23S rRNA genes. The distantly related bAvd protein, which also forms a homopentamer of four-helix bundles, has been suggested to interact with nucleic acids and a reverse transcriptase.	7.8358e-41
NC_017770.1\|WP_014682432.1\|4908233_4908953_+\|alpha/beta-hydrolase	gnl\|CDD\|226651	COG4188, COG4188, Predicted dienelactone hydrolase [General function prediction only].	3.46511e-10
NC_017770.1\|WP_014682430.1\|4905258_4906254_+\|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl\|CDD\|274473	TIGR03182, Pyruvate_dehydrogenase_E1_component_subunit_alpha, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	0
NC_017770.1\|WP_014682440.1\|4914722_4916054_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	3.08208e-55
NC_017770.1\|WP_042480314.1\|4919842_4920799_-\|stage-II-sporulation-protein-M	gnl\|CDD\|376676	pfam01944, SpoIIM, Stage II sporulation protein M. SpoIIM is on e of four stage II sporulation proteins that is necessary for the forespore inside the mother-cell to be properly internalized through the breakdown of peptidoglycans trapped between the membranes of the septum separating the forespore and the mother-cell. The four proteins working in sequence are SpoIIB, pfam05036, SpoIIM, SpoIIP, pfam07454, and finally SpoIID, pfam08486. D, M and P are in a complex with each other and the complex assembles in a hierarchical manner such that M, which serves as a membrane anchor, recruits P to the septum and P, in turn, recruits D to the septum.	7.46e-38
NC_017770.1\|WP_014682442.1\|4917081_4918257_-\|DUF4350-domain-containing-protein	gnl\|CDD\|379527	pfam14258, DUF4350, Domain of unknown function (DUF4350). This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length.	4.67547e-06
NC_017770.1\|WP_014682436.1\|4910592_4910850_+\|Txe/YoeB-family-addiction-module-toxin	gnl\|CDD\|284238	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system. YoeB_toxin is a family of bacterial toxins that forms one component of the type II toxin-antitoxin system in E. coli whose antitoxin is represented by YefM, found in pfam02604. The plasmid encoded Axe-Txe proteins in Enterococcus faecium act as an antitoxin-toxin pair. When the plasmid is lost, the antitoxin is degraded relatively quickly by host enzymes. This allows the toxin to interact with its intracellular target, thus killing the cell or impeding cell growth. These toxins are highly potent protein synthesis inhibitors, specifically blocking the initiation of translation. In the case of YoeB, it binds to the 50 S ribosomal subunit in 70 S ribosomes and interacts with the A site leading to mRNA cleavage at this site. As a result, the 3'-end portion of the mRNA is released from ribosomes, and translation initiation is effectively inhibited.	5.61008e-36
NC_017770.1\|WP_157604780.1\|4913281_4914652_+\|histidine--tRNA-ligase	gnl\|CDD\|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	1.68388e-141
NC_017770.1\|WP_014682437.1\|4910899_4912444_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143448	cd07130, ALDH_F7_AASADH, NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B. Alpha-aminoadipic semialdehyde dehydrogenase (AASADH, EC=1.2.1.31), also known as ALDH7A1, Antiquitin-1, ALDH7B, or delta-1-piperideine-6-carboxylate dehydrogenase (P6CDH), is a NAD+-dependent ALDH. Human ALDH7A1 is involved in the pipecolic acid pathway of lysine catabolism, catalyzing the oxidation of alpha-aminoadipic semialdehyde to alpha-aminoadipate. Arabidopsis thaliana ALDH7B4 appears to be an osmotic-stress-inducible ALDH gene encoding a turgor-responsive or stress-inducible ALDH. The Streptomyces clavuligerus P6CDH appears to be involved in cephamycin biosynthesis, catalyzing the second stage of the two-step conversion of lysine to alpha-aminoadipic acid. The ALDH7A1 enzyme and others in this group have been observed as tetramers, yet the bacterial P6CDH enzyme has been reported as a monomer.	0
NC_017770.1\|WP_014682434.1\|4909522_4910266_+\|SLATT-domain-containing-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	0.0077446
NC_017770.1\|WP_014682438.1\|4912817_4913270_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	2.15936e-67
NC_017770.1\|WP_014682431.1\|4906405_4908031_+\|pyruvate-dehydrogenase-complex-dihydrolipoamide-acetyltransferase	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	4.29565e-168
NC_017770.1\|WP_014682441.1\|4916053_4917028_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	2.47043e-98
NC_017770.1\|WP_014682446.1\|4920899_4921625_+\|RDD-family-protein	gnl\|CDD\|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	7.02035e-20

>NC_017770.1|WP_014682437.1|4910899_4912444_-|aldehyde-dehydrogenase-family-protein
MNLIDIPSILEELKITAHNPAWSTGLNWATGDGETSKTIVSPVDGKTIATASFASAGDYDHVVKTAQQAFKTWRLVPAPKRGEIVRQIGEELRAKKKALGALVSYEMGKSLQEGYGEVQEMIDICDFAVGLSRQLYGLTMHSERSRHRMYEQYHPLGIVGIISAFNFPVAVWSWNAALAWVCGDVCIWKPSEKTPLTAIACQKIAAQVFEKNGIAEGVSCLIIGDRTIGELMSNDTRVPLVSATGSTRMGKAVGAAVGQRLGRSLLELGGNNSIIISEHADLNMALPGVVFGAVGTAGQRCTTTRRLIIHESVYEAFKTKLANAYTQLRFGNPLDETNHVGPLIDKDAVQQYLNAIEKAKSEGATIVVEGGVLAGNGFESGCYVKPAIFEAENHYEIVQHETFAPILYIMKYKNIEEAIELQNGVPQGLSSAIMTTHLREAEKFLSHGGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKVYMRRQTNTINYGDDLPLAQGIKFDL
>NC_017770.1|WP_014682436.1|4910592_4910850_+|Txe/YoeB-family-addiction-module-toxin
MEVVFSEKAIEDLCFWKESNNIKAQEKITQLIKSFMESPFKGIGKPEPLKYGLAGYWSRRITAEHRLVYKVDNDKLIIIALRFHY
>NC_017770.1|WP_014682435.1|4910344_4910602_+|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MKVINYSDLRENLKSNLDYALEDEVTVKRPKGKGNVVILSEENYTSIMETLHLVSTEANRKHLIESIKQVEEGKVTSISVDDLWK
>NC_017770.1|WP_014682434.1|4909522_4910266_+|SLATT-domain-containing-protein
MPTHQQPNLIEKITQFIFIFCGIGFILTLSGLLAYSAYAVIPSSPFRELAAIIIVLMVLTLLFAILSFWASRKRIKNIWKTVEANFNQHESVSKTDYLIKRIAFSLEEFNASTKWMYRNVRLYKYSTVVLSGLATVILGLNFSYFFSERTIYLSVTKDIALVLNTVVTALATLSIFWNVDKYWIQNKIIKHQLRQLKSSIEFERSENRELTDEQLKSYFNKHQRILREFHLYWEGVMTEKDNGDKDH
>NC_017770.1|WP_042480306.1|4908954_4909428_-|hypothetical-protein
MKAASLNELKKELLGLEPNRLVEICLRITKYKKENKELLTYLLFESDNEHGYIESIKELIDEQFELIPKNNLYLGSKMLRKTLRTTNKFIKYSGHKETEAELLIYFCRKMKKSGIRIHNSTALTNLYQQQLKKINKAIDKLHEDLQFDYQQELDELH
>NC_017770.1|WP_014682432.1|4908233_4908953_+|alpha/beta-hydrolase
MNTKSVSTLIFILITFLACGQTIKPKQSILFDKSRNREIPIAVYSNGKDQKQPVAIISHGYGGGNTAYGFIANQLVSLGYYVVSIQHDLKGDIPMPTSGDIMVVRKPYWQRGVDNIQFVIAELKKIKKNLDFNKLLLVGHSNGGDMSMLFATEYPDQVDKVISLDNRRMTVPRTRSPRILYLKATDTEPDPGVLPTVDEQEEFSISIVYLKDGKHNDLWDGASTIVKKEVMGAIEGFLK
>NC_017770.1|WP_014682431.1|4906405_4908031_+|pyruvate-dehydrogenase-complex-dihydrolipoamide-acetyltransferase
MAEVVRMPKMSDTMTEGVLAKWHKKVGDKVKSGDVVAEVETDKATMDFESFQEGTLLYIGVEEGQAVPVDAVIAVLGAEGEDYKAALAAEGGNGKAAAAPAEAKAEAAPAPVQSSAPAVTPESLGATVIRMPLLSDTMTEGVINKWYKKIGDTIKSDDTIADVETDKATMEVTAYAEGTLLYIGVEEGKAAKVNDIIAIVGKPGTDVSPLLQAAPAAAPAKEEASAGSTAASATSAPVAEASTADANGRVKASPLARKIAEEKGIDLAQVKGSAEGGRIVKKDVETFTPSAAPTAKAATPGAGATTVAAPAVYGQESFTEVAVTQMRKTIARRLSESLFTAPHFYLTMSIDMDQAMEARKRINELGTIKISFNDIVLKAVAVALKKHPKVNSSWLGDKIRYNNHVNIGVAVAVEDGLLVPVVRFADTKSLSTISTEVKEYAQKAKDKKLQPADWEGSTFTISNLGMYGIDQFTAIINPPDACILAVGGISQVPVVKNGQVVPGNVMKVTLSCDHRVVDGATGSEFLQTLKGLLEEPLRLLV
>NC_017770.1|WP_014682430.1|4905258_4906254_+|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MSSIAITKETYLTWYEQMYMMRKFEERSGQLYGQQKIRGFCHLYIGQEAVAAGALSATRPDDGFITAYRDHALALGKGVSARECMAELYGKETGCSKGKGGSMHFFSKEHNFYGGHGIVGGQIPLGAGIAFASKYKGTDAVCLCFMGDGAVRQGALNETFNMAMIWNIPVIFICENNGYAMGTSVERTTNMPDIYKIGLGFDMPSEPVDGMSCEAVHEAVDRAVQRARAGEGPSFLEIRTYRYKGHSMSDPAKYRTKEEVEEYKAKDPLEQVKQTILQNKYANEAWFEQIEAKVKEEVEDSVKFAEESAYPDPSELYKDVYVQSDYPYIMD
>NC_017770.1|WP_052308720.1|4904324_4904870_-|C40-family-peptidase
MKRLLLLLVFVISANAVSAQSKSLKDFFTSKPEDKEISDPDSLGYLYYSQLFGFSIASKANTKLFDFVYDWLGTPYRFGGNSRKGIDCSRFVNKMYDAVYGAFLGGANSRDFYKNVKPVDKENLKEGDFVFFKIGKKYISHIGVYLGNGKFAHSSSSKGVSIADLDDPYFKRYFFKGGRIQ
>NC_017770.1|WP_157604618.1|4903920_4904079_+|hypothetical-protein
MGKRFHLIVEAFYFLGFADVFRFTSVNPIELAKDFVGGKEMVSFLRENFEEV
>NC_017770.1|WP_014682438.1|4912817_4913270_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MKILMVCLGNICRSPMAEGIMRDLIRKNNLNWEVDSCGTGSWHIGEAPDKRAQRTAQSFGVDITSLRARQFSIADFNEFDRIYVMDTSNHQNVLKMAPDEQSRQKVDLLLNSCMPGENCEVADPWFDESLFIPVYKQIEQACQKIIESNR
>NC_017770.1|WP_157604780.1|4913281_4914652_+|histidine--tRNA-ligase
MQIMKPSIPKGTRDFSPIEVARRTYIFDTIKRVFQKYGYQPIETPVMENLSTLTGKYGEEGDQLIFKVLNSGDFLSKVDAQKLEAKNSKSVTFDISEKALRYDLTVPFARYVVMHQNEIAMPFKRYQVQPVWRADRPQKGRYREFYQCDADVVGSESLLNEAEFVCIYDEALSNLGLQDFSIKINNRKILTGIAEIIGKPELIVDMTVAIDKLDKIGYDGVVKELIERGFTESDVEVLRPFIELKGSNEEKLAVLKQSLANSPTGKKGIEELETIFSYLTSFKLNKATVELDITLARGLNYYTGAIFEVKSNEVQMGSIGGGGRYDDLTGMFGLKGVTGAGISFGADRIYDVMLELNLFPESAVTSTKVLLTNFDAAAEKYALPILVQLRTNDINTELYPASAKLQKQMKYADAKQIPFVVLIGEEEMQSGKLTLKNMQSGEQEKLSVEEIIKKLK
>NC_017770.1|WP_014682440.1|4914722_4916054_-|DUF58-domain-containing-protein
MRFIKDLYLSNRFFAALIACGLLFVIAFFIPVLFIPAKLLFAIFILLTAIDFISLFSIKEAFFSRRFMAEKLSNGSENEIILYLENKYNFSVNVKVIDEIPHQFQKRDALFKESLKKGQTKKLKYLLRPVKRGEYEFGAINIFISSIIGLARRRFRFEQGKTVPVYPSFIQMRKYELLAISNRLQEIGIKRIRRIGHSSEFEQIKAYVPGDDTRTINWKATARKSSLMVNNYQDEKSQQVYCIIDKGRAMKMPFEGLSLLDYSINASLVLANSAMIKGDKAGIITFSSRISSVLKADKKPVHLQHILELLYNQRTNYQESDYESLFANIRLNINQRSLLVLFTNFESRAGMRRQLPYLQRLAKHHLLLVVFFENTELEELLDSKPENTEDIYLKTIAEKFSYDKKLIVKELNQHGIHTVLTPPSKLTVNTLNKYLEFKSRGLI
>NC_017770.1|WP_014682441.1|4916053_4917028_-|MoxR-family-ATPase
MEETTFQNRIDFEQLNQSVSKIKEELAKVIVGQEKFIELLITAIFADGHVLIEGVPGVAKTLTAKLMAKTIKSNFSRIQFTPDLMPSDVLGTSVFNPSASNFEFKQGPIFSNIILIDEINRSPAKTQAALFEVMEERQVTNDGITYPMAFPFLVMATQNPIDQEGTYRLPEAQLDRFIFKIEVKYPSLAEEILILNGHHTGFANKLDEISSVLDSNTIAFLREKIRQVHVEPKLIEYIAQIVNSTRDNKFLYLGASPRASVAILNASKALAAIRGRDFVTPEDIQELAYPVLRHRIILSPEKEMEGATADDIIKLIVQKLEVPR
>NC_017770.1|WP_014682442.1|4917081_4918257_-|DUF4350-domain-containing-protein
MKGNRKYIAILAAMIIAFGLIEYYRPKPIDWRITLSNKDKIPFGSYATFELLKDVFPKQSISSSRLPAFNQLTETNNNKGNYIFVTSYFAADENDTKELLKFVAKGNDLFIAATTFNGPFADTLKVHTGADFEEKQYVTKLLNVGKGRNFKFISPRENSFFDSLNHKTTVVLGRKSSGKPDFVKIKHGKGHVYLNVNSTAFSNYFVLDNATKDYAFQCLSYLPIKQVIWDEYTKQGRVGEDDVFRVLMEHPSLKWAYYIMILGIIIFIIFESKRRQRIIPIITPLPNNTLEFTKVVGALYFNKGDHHDAALKKINYLLEFIRTKFFERTNVIDDEFIEHIAEKTGWDKVKTKQLFEMIRWIKSRPEEYLLSEADLLLLNDLIEEFFEFVKK
>NC_017770.1|WP_014682443.1|4918259_4918985_-|DUF4129-domain-containing-protein
MKATFRVLFLLILLTAVRTSAGFASASPAISCPNDTTRVLTRLPLNSSIEKFNSDPEFQYKKDIAPQTDWWGKFWQWVYRLFDRLFSGLNYGNFWQYVFILIIAGTATFVILKLLGINLTALFSRRSADIDLPYETLHEDVRIMDFDKLIADAIDNRNFRLAVRLYYLKTLKELNNRSMITWKPEKTNHNYITELSALHLKEGFQQMTHQFEFVWYGEFDLAENEFNAIRQSFLSFHQQII
>NC_017770.1|WP_014682444.1|4918968_4919859_-|hypothetical-protein
MQYKINLREERDFGQKINAVFTFLQQNFKPLFRSLLFIAGPTSLLGGIFMGLHQSRFMDFALNENPSETIGNYNIFRDLFNPNYFLAILFLIISFILVFQSVYGYLVAYLEDKNRPITTDMVWEHVKQKFFFSFFAIIVLGITMMLASLVFLIPGIYLAVAFQLALIIIAMEKIDVFELISRCIYLIRGKWWSTFGLIFIISMIQGMMGVVFNVPLYIITFAKAFHVGEVNDSNNFFFIISTVISTVGTVLLYSLSALAMAFQYFNLVERKEGVGLLEEVDKLGKSQPINDNEGDF
>NC_017770.1|WP_042480314.1|4919842_4920799_-|stage-II-sporulation-protein-M
MREVVFVQKNEQKWKNFENNKDGSPDEIAENFIELTDDLAYSRTFYADSATTRYLNAVTSKFYLNIYKNKKESKNRFVTFWKYELPLTLATHRKQLLYSFLLFMIGMSIGVLSAAKDETFVRLILGDTYVNQTIANIEKGDPMAIYKSQGQADMFMGITINNIKVSFMAFVAGVLFSLGTAWILFSNGVMLGAFQFFFYQKGLLLTSVLSIWIHGTLEISAIILAGCAGLVMGNSILFPKTYSRLESFKQGARNGLKIVIGLVPVFIMAGFLESFITRYTQMPMALSLFIILASLSFVIYYFIIYPYRLTKPLNAVQD
>NC_017770.1|WP_014682446.1|4920899_4921625_+|RDD-family-protein
MSTNISVQTAQNVYLDYELASVGDRILSTLIDWLIIVVYFLFWVVVFSTISQEPGFAFLSLLSLPVLFYHLLMEIFFNGQSIGKRAMKIQVVKLDGSTPSIGDYLLRWLLRIIDISTFYGVIGLVTIVANGKGQRIGDLAAGTTVVKLNSNKDYHDIPVTRIDPSYKVNFPEVTLLNDADINLIKKIINRSLKANREDMLGPVANKVKEITGVQSPLSDYVFLQIVISDYNHLAGITESVG
>NC_017770.1|WP_014682447.1|4921719_4922082_+|four-helix-bundle-protein
MGTFRQLLVYKKGFELAQEIYSITKNFPKEELYSLTDQIRRSSRSVCANIGEGYRKRKYPKHFISKLSDSDMENSETQVWLDFALANHYISQQIYLELDNKADEIARLLNYMMNNVEKFQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017770_2	2.2\|616212\|60\|NC_017770\|PILER-CR	616212-616271	60	NC_017770.1	616288-616347	1	0.983

1. spacer 2.2|616212|60|NC_017770|PILER-CR matches to position: 616288-616347, mismatch: 1, identity: 0.983

gacgatttccattacctgggttctcatacgaaggacgacctgaattgttattacccggac	CRISPR spacer
gacgatttccattacctgggttctcatacgaaggacggcctgaattgttattacccggac	Protospacer
*************************************.**********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017770_3	3.1\|1051106\|27\|NC_017770\|CRISPRCasFinder	1051106-1051132	27	NC_011412	Clostridium perfringens plasmid pCP8533etx, complete sequence	34733-34759	4	0.852
NC_017770_3	3.1\|1051106\|27\|NC_017770\|CRISPRCasFinder	1051106-1051132	27	NC_014634	Ilyobacter polytropus DSM 2926 plasmid pILYOP02, complete sequence	4415-4441	6	0.778
NC_017770_5	5.1\|2540729\|32\|NC_017770\|CRISPRCasFinder	2540729-2540760	32	MH622943	Myoviridae sp. isolate ctbc_4, complete genome	38305-38336	10	0.688

1. spacer 3.1|1051106|27|NC_017770|CRISPRCasFinder matches to NC_011412 (Clostridium perfringens plasmid pCP8533etx, complete sequence) position: , mismatch: 4, identity: 0.852

atttattaatcgtttagtataaaaaaa	CRISPR spacer
agtgatttatcatttagtataaaaaaa	Protospacer
* * *** ***.***************

2. spacer 3.1|1051106|27|NC_017770|CRISPRCasFinder matches to NC_014634 (Ilyobacter polytropus DSM 2926 plasmid pILYOP02, complete sequence) position: , mismatch: 6, identity: 0.778

atttattaatcgtttagtataaaaaaa	CRISPR spacer
gaatattattcgtttagtatcaaaaag	Protospacer
.  ***** *********** *****.

3. spacer 5.1|2540729|32|NC_017770|CRISPRCasFinder matches to MH622943 (Myoviridae sp. isolate ctbc_4, complete genome) position: , mismatch: 10, identity: 0.688

ttgaatcatctattataattatccattccgta	CRISPR spacer
gaaaatcatttattaaaattatccatgttatt	Protospacer
  .******.***** ********** ...*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

970088 : 977827

Cellulophaga_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014679140.1\|970088_970820_-	serine/threonine protein phosphatase	S0A0Y6	Cellulophaga_phage	1.3e-39	35.2
WP_014679141.1\|970923_971880_-	ADP-ribosylglycohydrolase family protein	A0A1S6UB21	Serratia_phage	1.9e-38	33.4
WP_014679142.1\|971886_972429_-	RNA 2'-phosphotransferase	A0A2R2ZGT8	Clostridioides_phage	1.3e-47	51.4
WP_014679143.1\|972425_972938_-	O-acetyl-ADP-ribose deacetylase	A0A0K1L687	Scale_drop_disease_virus	6.5e-30	44.4
WP_014679144.1\|972939_973485_-	NADAR family protein	L7RD33	Acanthamoeba_polyphaga_moumouvirus	1.2e-34	47.2
WP_014679145.1\|974352_975117_+	hypothetical protein	NA	NA	NA	NA
WP_014679146.1\|975262_977827_+	DNA translocase FtsK 4TM domain-containing protein	A0A218M9A2	Mycobacterium_phage	3.5e-71	43.7

DBSCAN-SWA_2

1530269 : 1538068

uncultured_Caudovirales_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014679591.1\|1530269_1531493_+	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	3.7e-71	45.5
WP_014679592.1\|1531529_1532042_-	HPP family protein	NA	NA	NA	NA
WP_014679593.1\|1532147_1533485_-	vanadium-dependent haloperoxidase	A0A1V0SKZ4	Klosneuvirus	2.2e-21	26.5
WP_157604684.1\|1533611_1534145_-	ester cyclase	A0A2K9L9F9	Tupanvirus	8.6e-25	34.9
WP_014679595.1\|1534262_1534877_-	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	7.1e-07	23.9
WP_014679596.1\|1534940_1535450_-	GNAT family N-acetyltransferase	G9BWD5	Planktothrix_phage	1.4e-16	32.7
WP_014679597.1\|1535670_1536417_+	EcsC family protein	NA	NA	NA	NA
WP_014679598.1\|1536631_1538068_-\|tRNA	asparagine--tRNA ligase	A0A2K9V902	Bandra_megavirus	3.5e-81	38.6

DBSCAN-SWA_3

2258050 : 2267765

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014680189.1\|2258050_2259838_+	elongation factor 4	A0A2K9L6L3	Tupanvirus	1.7e-24	44.8
WP_014680190.1\|2259982_2260861_+	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	1.1e-29	33.8
WP_174270031.1\|2261004_2261586_+	7-carboxy-7-deazaguanine synthase QueE	A0A142F2D5	Mycobacterium_phage	1.1e-14	43.6
WP_157604700.1\|2261971_2263849_+	PD40 domain-containing protein	G3M9Z0	Bacillus_virus	1.8e-05	32.4
WP_014680193.1\|2263852_2264287_+	hypothetical protein	NA	NA	NA	NA
WP_014680194.1\|2264303_2264708_+	thiol-disulfide oxidoreductase DCC family protein	NA	NA	NA	NA
WP_014680195.1\|2264704_2265511_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.9e-55	47.4
WP_014680196.1\|2265575_2267765_-	DNA helicase RecQ	A0A2K9L3P7	Tupanvirus	8.0e-85	38.8

DBSCAN-SWA_4

2536433 : 2559686

Synechococcus_phage(16.67%)

transposase,tail,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014680430.1\|2536433_2539928_-\|plate	baseplate J-like protein	NA	NA	NA	NA
WP_014680431.1\|2539946_2540363_-	GPW/gp25 family protein	A0A0E3FJY3	Synechococcus_phage	8.2e-07	33.7
WP_014680432.1\|2540366_2540657_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_014680433.1\|2540816_2542592_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_014680434.1\|2542847_2543543_-	hypothetical protein	NA	NA	NA	NA
WP_014680435.1\|2543542_2543716_-	hypothetical protein	NA	NA	NA	NA
WP_014680436.1\|2543958_2544402_-\|tail	phage tail protein	NA	NA	NA	NA
WP_014680437.1\|2544401_2544836_-\|tail	phage tail protein	A0A059XEM3	uncultured_phage	1.5e-30	56.6
WP_014680438.1\|2544885_2546298_-\|tail	phage tail sheath family protein	A0A1J0GW47	Streptomyces_phage	5.6e-23	35.1
WP_014680439.1\|2546330_2547086_-	hypothetical protein	NA	NA	NA	NA
WP_014680440.1\|2547095_2547647_-	DUF4255 domain-containing protein	NA	NA	NA	NA
WP_014680441.1\|2547951_2549040_+	alkaline phosphatase family protein	NA	NA	NA	NA
WP_014680442.1\|2549139_2549700_-	PAS domain-containing protein	A0A1B0V854	Salmonella_phage	3.6e-21	41.0
WP_014680443.1\|2550353_2552486_+	ribonucleoside triphosphate reductase	D9ZNH0	Clostridium_phage	6.8e-121	41.7
WP_014680444.1\|2552457_2552637_+	hypothetical protein	NA	NA	NA	NA
WP_014680445.1\|2552578_2553295_+	anaerobic ribonucleoside-triphosphate reductase activating protein	NA	NA	NA	NA
WP_014680446.1\|2553325_2554546_+	hypothetical protein	NA	NA	NA	NA
WP_014680447.1\|2554542_2554992_+	CopD family protein	NA	NA	NA	NA
WP_014680448.1\|2555095_2557120_-	beta-galactosidase/beta-glucuronidase	NA	NA	NA	NA
WP_014680449.1\|2557169_2558054_-	EamA family transporter	NA	NA	NA	NA
WP_014680450.1\|2558785_2559052_+\|transposase	transposase	NA	NA	NA	NA
WP_052308574.1\|2559084_2559459_+	hypothetical protein	NA	NA	NA	NA
WP_052308575.1\|2559452_2559686_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	5.6e-13	44.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017770

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection