CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_021171	Bacillus sp. 1NLA3E, complete sequence	8 crisprs	DEDDh,DinG,RT,csa3,cas14j,cas14k,cas3,PrimPol	3	4	3	0

1. NC_021171

CRISPR-Cas detection and classification

Crispr_ID: NC_021171_1

• CRISPR_ID: NC_021171_1
• CRISPR_location: 546062-546158
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021171_1

Consensus_repeat	Method
AACAAAATCTAAACGTTTACATT	CRISPRCasFinder

spacers of NC_021171_1

>1.1|546085|51|NC_021171|CRISPRCasFinder
ACAACTGATAAATTAATTACTTACAAAACTCGTTAAATCATATTTTTTTGC

CRISPR arrays and Neighbor proteins around NC_021171_1

CRISPR arrays

The CRISPR arrays of NC_021171_1

>merge|NC_021171|1|546062-546158|CRISPRCasFinder
AACAAAATCTAAACGTTTACATTACAACTGATAAATTAATTACTTACAAAACTCGTTAAATCATATTTTTTTGCGACAAAATCTAAACGTTTACATT

>NC_021171|1|1|546062-546158|CRISPRCasFinder
AACAAAATCTAAACGTTTACATT	ACAACTGATAAATTAATTACTTACAAAACTCGTTAAATCATATTTTTTTGC
GACAAAATCTAAACGTTTACATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_015592349.1|548537_549554_+|aldose-1-epimerase-family-protein	unknown	unknown	gnl|CDD|185703
NC_021171.1|WP_015592352.1|552261_553401_+|glycerate-kinase	unknown	unknown	gnl|CDD|376844
NC_021171.1|WP_015592336.1|535003_535546_+|DUF1697-domain-containing-protein	unknown	unknown	gnl|CDD|377954
NC_021171.1|WP_015592348.1|547117_548464_+|L-fucose:H+-symporter-permease	unknown	unknown	gnl|CDD|340952
NC_021171.1|WP_015592350.1|549566_550487_+|ribokinase	unknown	unknown	gnl|CDD|274000
NC_021171.1|WP_015592339.1|538095_538599_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|213222
NC_021171.1|WP_015592353.1|553443_554472_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|226355
NC_021171.1|WP_015592351.1|550944_552246_+|GntP-family-permease	unknown	unknown	gnl|CDD|225330
NC_021171.1|WP_083935041.1|557132_557249_+|hypothetical-protein	unknown	unknown	gnl|CDD|225277
NC_021171.1|WP_015592346.1|544874_545888_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525
NC_021171.1|WP_015592343.1|541581_541971_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015592341.1|539807_541103_+|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NC_021171.1|WP_187292177.1|546401_547073_+|deoxyribose-phosphate-aldolase	unknown	unknown	gnl|CDD|234784
NC_021171.1|WP_015592344.1|541971_542343_-|DUF2089-domain-containing-protein	unknown	unknown	gnl|CDD|378280
NC_021171.1|WP_015592355.1|556401_556887_+|hypothetical-protein	unknown	unknown	gnl|CDD|226695
NC_021171.1|WP_015592338.1|537504_538071_+|DUF4256-domain-containing-protein	unknown	unknown	gnl|CDD|339073
NC_021171.1|WP_015592342.1|541305_541578_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015592340.1|538821_539316_+|DUF1456-family-protein	unknown	unknown	gnl|CDD|227144
NC_021171.1|WP_015592354.1|554583_556191_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|236901
NC_021171.1|WP_015592337.1|535758_537348_+|FAD-binding-protein	unknown	unknown	gnl|CDD|225307

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_015592349.1|548537_549554_+|aldose-1-epimerase-family-protein	gnl|CDD|185703	cd09269, deoxyribose_mutarotase, deoxyribose mutarotase_like. Salmonella enterica serovar Typhi DeoM (earlier named as DeoX) is a mutarotase with high specificity for deoxyribose. It is encoded by one of four genes beonging to the deoK operon. This operon has also been found in Escherichia coli where it is more common in pathogenic than in commensal strains and is associated with pathogenicity. It has been found on a pathogenicity island from a human blood isolate AL863 and confers the ability to use deoxyribose as a carbon source; deoxyribose is not fermented by non-pathogenic E.coli K-12. Proteins in this family are members of the aldose-1-epimerase superfamily. Aldose 1-epimerases, or mutarotases, are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. Site directed mutagenesis of this latter histidine residue renders Salmonella enterica DeoM inactive.	3.67152e-171
NC_021171.1|WP_015592352.1|552261_553401_+|glycerate-kinase	gnl|CDD|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	0
NC_021171.1|WP_015592341.1|539807_541103_+|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.14563e-151
NC_021171.1|WP_015592351.1|550944_552246_+|GntP-family-permease	gnl|CDD|225330	COG2610, GntT, H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism].	1.61192e-49
NC_021171.1|WP_015592350.1|549566_550487_+|ribokinase	gnl|CDD|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	6.3139e-142
NC_021171.1|WP_015592344.1|541971_542343_-|DUF2089-domain-containing-protein	gnl|CDD|378280	pfam09862, DUF2089, Protein of unknown function (DUF2089). This domain, found in various hypothetical prokaryotic proteins, has no known function. This domain is a zinc-ribbon.	7.47005e-58
NC_021171.1|WP_015592353.1|553443_554472_-|helix-turn-helix-domain-containing-protein	gnl|CDD|226355	COG3835, CdaR, Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms].	1.18817e-69
NC_021171.1|WP_083935041.1|557132_557249_+|hypothetical-protein	gnl|CDD|225277	COG2414, COG2414, Aldehyde:ferredoxin oxidoreductase [Energy production and conversion].	1.33275e-05
NC_021171.1|WP_015592346.1|544874_545888_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	5.06233e-120
NC_021171.1|WP_015592336.1|535003_535546_+|DUF1697-domain-containing-protein	gnl|CDD|377954	pfam08002, DUF1697, Protein of unknown function (DUF1697). This family contains many hypothetical bacterial proteins.	4.05769e-55
NC_021171.1|WP_187292177.1|546401_547073_+|deoxyribose-phosphate-aldolase	gnl|CDD|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	7.80586e-125
NC_021171.1|WP_015592340.1|538821_539316_+|DUF1456-family-protein	gnl|CDD|227144	COG4807, COG4807, Uncharacterized protein conserved in bacteria [Function unknown].	6.65289e-52
NC_021171.1|WP_015592337.1|535758_537348_+|FAD-binding-protein	gnl|CDD|225307	COG2509, COG2509, Uncharacterized FAD-dependent dehydrogenases [General function prediction only].	2.37235e-151
NC_021171.1|WP_015592338.1|537504_538071_+|DUF4256-domain-containing-protein	gnl|CDD|339073	pfam14066, DUF4256, Protein of unknown function (DUF4256). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 190 amino acids in length.	2.15159e-141
NC_021171.1|WP_015592348.1|547117_548464_+|L-fucose:H+-symporter-permease	gnl|CDD|340952	cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.22447e-128
NC_021171.1|WP_015592354.1|554583_556191_-|PAS-domain-S-box-protein	gnl|CDD|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.45016e-56
NC_021171.1|WP_015592339.1|538095_538599_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.11956e-47
NC_021171.1|WP_015592355.1|556401_556887_+|hypothetical-protein	gnl|CDD|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	1.40981e-11

Protein sequences

>NC_021171.1|WP_015592346.1|544874_545888_+|LacI-family-DNA-binding-transcriptional-regulator
MDSKPNIQDVARVAEVSIATVSRVINNQGGVRKATEERILKAIQELGYIRNAAARTMKRKETKTIGVIVPDIKNPFFPLVMAGIEQKAREKDYFTILSSTNESQNIEEKIVKNFIERGVDGVIITTANENGEHLKLLQEQNIPMVAVDRSIRSFEVDTVLVDNIKGSYQAVQHLILQGHRKISIICGPQNTTPGLERYLGYKKALEDYNIPLDEKLVIQGDFGEHSGYLATEKLRELDERPTAIFSSNNLMTIGCMRALDDLNWKLGYEVSFIGFDDVDIATFLNPKLSVVARPMTAVGEIAFMFLHERIHFKDLPKRQYSLPPELIIRQSCRLIKN
>NC_021171.1|WP_015592344.1|541971_542343_-|DUF2089-domain-containing-protein
MAYPLISECPVCSKQLKITKLQCTHCHTTIENEFELSNFASLSKEQLNFIETFLKCRGNIKEVEKELGVSYPTVRGKLDDIISSLGYSTTKKVEIDRKKVILMLEKGEITAEEAISILNGEES
>NC_021171.1|WP_015592343.1|541581_541971_-|hypothetical-protein
MNEEISRILTMVEEGKLDKDKAAELIDALQGKGKQVNLNKQTSSPYLDKMLKIRATSEQGDNVNVNLPIKLVKAVLRVGTSIAERIPEAEKYVKDIDVDLLIEAIENELDGQIVDITSAKGEKVSVVIE
>NC_021171.1|WP_015592342.1|541305_541578_-|hypothetical-protein
MMKVKIKAKGRRYFIPVPYALLHLFIGVVTSKRILAIANRSIEKGGNKKFQIPNISRDDLKPLLRELSDQKGLMLVETILKDGTEVSIKL
>NC_021171.1|WP_015592341.1|539807_541103_+|NCS2-family-permease
MKNYFQFSERNTSFKQESIAGITTFLSMAYILVVNPVILSQTGMDKGALFTATALSAIIGSLLIGLIANYPIGIAPSMGINAFFTFTVCIGMKIPWETALAGVFIAGVLFMILSLLKIREKIINVIPQDLKHAIAAGIGFFVALIGLKNSGIVTANEATMVGLGNLNSPPTLLAIAGFIITIILLNKGIKGGIFYGMVLSTILGMLFGIIDKPEAIIGKIPSLQPTFGVVFNHLDDVLSPKVLAVIFTFLFVAFFDTAGALIAIASQAGLMKDNQIPNAGKALLADSMSTIAGSVLGTSTTASFVESSAGIAVGGRTGFTAIVISACFTVSLFFSPILSIVTPEVTAPALIIVGALMATEISKINWSNFTIVIPCFVTIIMMPLTFSVATGIALGFILYPISMIAMGKTREVHPIMSVLCLTFIFYFVYVI
>NC_021171.1|WP_015592340.1|538821_539316_+|DUF1456-family-protein
MLMENNDILIRLRYALDIKNNDMVEIFKLGGIETTKEEVLEILTKSTNDEAENEYIVKLNNMKLESFLNGFIIFKRGKQDPKPGLPESPPLSNECVNNFLLKKLKIALALTSEDMIDILKEAGVTITKGELSAILRKVGHKNYKECGDKYARNFLKGLTIKYRG
>NC_021171.1|WP_015592339.1|538095_538599_+|ATP-binding-cassette-domain-containing-protein
MGFIFQHSYLLKNLPIRDNIVLPGFKSGKLSREKVNQHVDELMVKTGIDNVAKHDIKKVSGGQLQRAAICRALINQPDILFGDEPTGALNSSTSRDVMDIINTVNTEGTTVIIVTHDAKVAAWAGRVIFLMDGKIHDELTLGKYDGDEKKKPSREKRLSEWLEKQEF
>NC_021171.1|WP_015592338.1|537504_538071_+|DUF4256-domain-containing-protein
MNNEKRKLSPEQREEILGILKGRFDKNMDRHKGLEWVKVQTKLETNTEKLWSLNEMERTGGEPDVIVHDKQVGEYIFYDCSAESPKGRRSVCYDREALESRKEHKPKNSAIDMAADMGIEILTEEQYREIQKLGNFDTKTSSWVKTPPNIRNLGGAIFCDRRYDTVFVYHNGAESYYAARGFRGSLMV
>NC_021171.1|WP_015592337.1|535758_537348_+|FAD-binding-protein
MLRISNIKLRADFDPSKENELLAQKIQKILRVKQDKILSFSISKKSIDAREKSNVQLVYSVDVEIENERSYLGIKDVSSYNPLEYGIKKTNKTTRPVVVGSGPAGLFCALVLAEHGLNPVVVEQGMDVDKRKMAVEKFWKDGELETSSNVQFGEGGAGTFSDGKLTTGVKNTRIPKVLKEFVEAGAPSKIAYLAKPHIGTDILITVVRNIRKKIERLGGEVRFETKMKELIIENGEVRGVLLDRHGESETIETDAVVLAIGHSARDTFYMLKDLGVDMIPKPFAVGVRIEHHQKDIDLQQFGSFANNPLLGASDYKLNAHLPNGRGVYTFCMCPGGHVVAAASEKNAVVTNGMSYSARSGENANSALLVSITPNDFNGDVLAAIEFQRKLERKAFELGGRNYFAPVQLVGDFLVNKGSKQLGDIIPTYTPGVTPTDLRECLDDFIVDSLKDGLRVMDKKLAGFIKHDAVLSAVESRSSSPVTIRRNPLTFESNIKGLYPCGEGAGYAGGITSSAVDGIKCAEALMEIEN
>NC_021171.1|WP_015592336.1|535003_535546_+|DUF1697-domain-containing-protein
MRKYIAFLRGINVGGKNKISMPELKNLFEQNGFDDVATYINSGNIIFTSDKKDEKKLKEECEVLIKSKFQLNIPVSIISVNDLIAALNHAPLWWGQDKDSKHNAIFVIPPTTVEEVIEDVGAIKPEYEKVDHYGRVIFWSAPIETFSRTRWSKIVGSSMYNSITIRNSNTVRKLLQLANR
>NC_021171.1|WP_187292177.1|546401_547073_+|deoxyribose-phosphate-aldolase
MSMNTAKMIDHTLLKADSLKEQIVELCAEAREYGFASVCVNPVWVKTAAEELAASDVKVCTVIGFPLGASTSSVKAFETMDAIKNGATEVDMVISIGLLKSGNEQAVEEDIRGVVDAANGKALVKVIIETSLLTDKEKVLACEMSLRAGADFVKTSTGFSTGGATVEDVSLMRRVVAEKAGVKASGGIRDLNDLKAMAEAGANRIGASSGVKIMKGEMVESGY
>NC_021171.1|WP_015592348.1|547117_548464_+|L-fucose:H+-symporter-permease
MTSKNLIQLPDGYLNRTPIFQFILLSMLFPLWAVAASLNDILITQFKHVFELSDFASALVQSAFYGGYFLVAIPASMVIKKTNYKLAIITGLLFYIAGCTLFYPASEMATYTMFLFAIFSIAIGLGFLETAANTYSSMIGPRQFATLRLNISQTFYPIGSISGILLGKYLVFQEGASIEAQMSKMSPEEARVFGLQMLQHTLEPYKYIIFVLIGVLILFVFTKFPICKPVIEKAKTTVKSPGLLQTLKYLGGNKSFRKGIAAQFLYVGMQVTVWSFTIRLALDLNPDINERIASNFMVFSFIAFFVGKFIANFLMTRFAPSKVLTVYSIIGAALLAFVAFVPSMAAVYAAVAVSMLFGPCWPTIYAETLEVVKEKKYTEMAGAVLVMSIVGGAVIPAAQGFASDLFGSMQLSFLIPMVCFIYIGFYFYGKMKRNAAEQNTEEPLKVAK
>NC_021171.1|WP_015592349.1|548537_549554_+|aldose-1-epimerase-family-protein
MASGKVELQRAYFTDSSKIIFRNDEMTASLFRYPSGVEAIELKNLRGRMVVLPYMGQMIWDLEFDGANLKMKNMFSQPKKAASVIDTYGCFAFHSGLIRNGCPGPEDDHDLHGEMPCAEMDRAWLEITDDGIKICGETEYVKGFGHHYLARPTVKMFSRETFIEINMNVKNLSGSEMPLQYMFHTNYAYLENAVMKQNIPASAFKLRESIPGHVKPTEKWLDYNKKLLSGDEMITALNQPEMYDPEIVFFADKLDHYLEDAEFEMVSHDGTAFFTRFSTSEFNYATRWILHNSDQQVGAFVLPATCRPEGFLAAERSGTLLKLNAGEEKSFTVVTGKK
>NC_021171.1|WP_015592350.1|549566_550487_+|ribokinase
MDIAVIGSNMVDLISYIDKMPKEGETLEAPDFEIGCGGKGANQAVAAAKMGSKVMMVTKVGDDLFADNTIQNLESYGIDTEFTNKVLGTSSGVAPIFVDPESKNRILIIKGANQQLLPVDVDRAADKLKQCSLIVLQLEIPLETIYRAIEFGNEHGIPVILNPAPASKNLDFSYVCKCDFFIPNESELEILTGMPVETDEQIKAAASTLIEKGVKDVIVTMGSRGVMWVTKGEVHIVDSHTVAAIDTTGAGDAFIGCFAHYFVQDGDVLHAIKMATAFAALSVTKRGTQTSYPSFDEVEQFMNVMV
>NC_021171.1|WP_015592351.1|550944_552246_+|GntP-family-permease
MATAIDISWIGALSGLALAIILILFRLAPTYSLILGAIVGAFIGGANFAEAVQILITGTQSVQGTVIRIIAAGVFAGVMMESGAAETIAKVIVDKLGGTKAMLSLALATMIITAVGVFIPVAVLIVAPIALSVGNKMGYSKVAMLVALSGGGKAGNIISPNPNTIAAAGGFKLDVNQVMIGGLVPAIIGVIVTVIIASLIKYKGTKVTDAEAAELEQASSTNLPALSKALVTPIIAIVLLMISPIGSMIGIDFLAKLKIDSLFILPFAGVMGSLALGKRKQIMDYCTAGLNRMTPTILIIIGAGAIGGLITASDLPEQVVALVNSSGISGTFLAPIAGILMAAATASTSTGVILATGSFSDAILNTGVAPLAAAVMTHAGATVIDHLPHGTYFHVTRNAMNMSMKDRMKVVLFESIVGLTMTIVAVILYGFIL
>NC_021171.1|WP_015592352.1|552261_553401_+|glycerate-kinase
MMGKTFLLAPDSFKESMTAKEVCEAMEIGIKRAIPDAECIHVPMADGGEGTVQSLIDATGGTLIKKEVMGPLGTPVMAQYGILGDGKTGVIEMASASGIHYVTKETKNPFITTTFGTGELIKDCIEQGITDIILGIGGSATNDGGTGMAVALGYKFLDKDRNELPFGGGYLGELDTIDPSDVNPQLKNVNILVASDVTNPLCGERGASAVFGPQKGATPEMVQILDNNLRHYGKVVKEQLGIDMVDVPGAGGAGGLGAGLLAFTNSTMKKGIEIVIKYTNLKEKLQNVDYCFTGEGGIDFQTKFGKAPYGVSQAAKSVNSDIKVIALAGYVGKDVETLYDEGFDAIFGIVPGAADLDTLLEQGKENVARTSESIARLLK
>NC_021171.1|WP_015592353.1|553443_554472_-|helix-turn-helix-domain-containing-protein
MYELTHHQAQNIVDRMMKDIPYNINIMDKTGVIIGSGNKKRIGTLHHGAVAAIKQKKISEIKQDEEFVKKGINLPIELNGDIVGVVGISGEVMETRPFGNLLKSAVILLIEQSVASEKENLEKNLKQEFFSFMTDSNTTYTKELTDQALAYDIQLNKPSQMVYLECPNEIEEDFFKNFPSFNTSNHSLCIVVQETNKIEALQEQIENQYPDAFISISKMNDKISDGFLQAKSAMRVLKGLFLNKKVISYEKCEFIADMSELQRNDAKTGRMVHLFKKNDELIKTLQVYLNCNQNANETASQLIIHRNTLNYRLNRIFKITGKDPKNILELVELLFMLINREK
>NC_021171.1|WP_015592354.1|554583_556191_-|PAS-domain-S-box-protein
MAEKEPYYITESKRMCIESGMDPNEIAKPKGFMTNQVLDSKRKEYSEILSVVSFFSNKLIDSLNGTPILIVISDSEGYLLDMVGDETIRTAIEQFGIKLGSLFRQEDTGTNVVSLALKHRHPVRLKGEDHYHKFLYEVACYGVPFHYTDEDNLLGSVCIMVPILFQNPLFLTMLSQVVDSIERELLLRKKNRKLNILNQIMLCRTRNGIVITDEKGITIEFNDFAQQIFNQTSSSVIGKSIYDSDLTGEFFKRVIEFEEKYENEVLTFNNINSDQVVCLFDAQPIYEDEKVIGAFGQFRDITDRHLIEEKIKESEKQALAGRIAAGIAHEIRNPLTTVRGYLQFLEKDVDSRTSHLFSSLLIPEIDRVNKIISDFLSIAKASYKELERINIQHFFIDYLLKFLKSESLLYNVEINVEILPETKNLSILCNREELLQVFINLFQNSLQAKTDTPLIINISTNLVNSHVQFIFNDNGKGIHSSVLTHIFEPFFSTKDSGTGLGLSVSRKIVENHNGTMYASSNERGTKFIIELPYFN
>NC_021171.1|WP_015592355.1|556401_556887_+|hypothetical-protein
MKIIRRRLEIMPLHPLVVHFPIALLLTATLIEIVNLFLKKESVSRMGTVLVFVGVLLGFVSLATGDPAEAFAFKNWGRGIHDTVELHSFLAGTSVTLFAIVAVIKLFGKRLKFNKNLIIALVIVFSITGSTTLAITGHLGGKIVYQHEQLTSKSGGTVDDD
>NC_021171.1|WP_083935041.1|557132_557249_+|hypothetical-protein
MACLIHDAGNGAGQGGFGGVWGSENLKAISILGTGGFR

Crispr_ID: NC_021171_2

• CRISPR_ID: NC_021171_2
• CRISPR_location: 1258560-1258635
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021171_2

Consensus_repeat	Method
AAGTAGCGCCCAAAAAGATGAAAA	CRISPRCasFinder

spacers of NC_021171_2

>2.1|1258584|28|NC_021171|CRISPRCasFinder
AGGCGTCAATTGGGTAACTACTCCAGTG

CRISPR arrays and Neighbor proteins around NC_021171_2

CRISPR arrays

The CRISPR arrays of NC_021171_2

>merge|NC_021171|2|1258560-1258635|CRISPRCasFinder
AAGTAGCGCCCAAAAAGATGAAAAAGGCGTCAATTGGGTAACTACTCCAGTGAAGTAGCGCCCGAAAAGATGAAAA

>NC_021171|2|2|1258560-1258635|CRISPRCasFinder
AAGTAGCGCCCAAAAAGATGAAAA	AGGCGTCAATTGGGTAACTACTCCAGTG
AAGTAGCGCCCGAAAAGATGAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_015592964.1|1256909_1257791_+|DUF4349-domain-containing-protein	unknown	unknown	gnl|CDD|379526
NC_021171.1|WP_041580350.1|1253094_1253979_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NC_021171.1|WP_015592967.1|1260430_1260643_-|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein	unknown	unknown	gnl|CDD|377805
NC_021171.1|WP_015592963.1|1256236_1256779_+|peroxiredoxin	unknown	unknown	gnl|CDD|239313
NC_021171.1|WP_041580352.1|1263135_1263282_-|YjcZ-family-sporulation-protein	unknown	unknown	unknown
NC_021171.1|WP_015592969.1|1262400_1262955_-|peptide-deformylase	unknown	unknown	gnl|CDD|234668
NC_021171.1|WP_015592962.1|1254824_1255952_+|N-acetyldiaminopimelate-deacetylase	unknown	unknown	gnl|CDD|349920
NC_021171.1|WP_015592959.1|1251522_1253040_+|MFS-transporter	unknown	unknown	gnl|CDD|341045
NC_021171.1|WP_015592966.1|1258759_1260427_-|ribonuclease-J	unknown	unknown	gnl|CDD|223668
NC_021171.1|WP_051120199.1|1263536_1264163_+|YkyA-family-protein	unknown	unknown	gnl|CDD|378419
NC_021171.1|WP_015592956.1|1249526_1250483_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293812
NC_021171.1|WP_015592957.1|1250662_1250899_+|YkuJ-family-protein	unknown	unknown	gnl|CDD|370128
NC_021171.1|WP_015592973.1|1266771_1268109_+|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl|CDD|237001
NC_021171.1|WP_015592974.1|1268112_1269522_+|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|235798
NC_021171.1|WP_015592968.1|1261582_1262353_+|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|319819
NC_021171.1|WP_015592965.1|1257861_1258521_+|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223643
NC_021171.1|WP_015592971.1|1264563_1265676_+|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	unknown	unknown	gnl|CDD|213783
NC_021171.1|WP_015592972.1|1265679_1266657_+|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl|CDD|223101
NC_021171.1|WP_015592958.1|1251020_1251467_+|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341400
NC_021171.1|WP_015592961.1|1254046_1254757_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	unknown	unknown	gnl|CDD|132571

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_015592964.1|1256909_1257791_+|DUF4349-domain-containing-protein	gnl|CDD|379526	pfam14257, DUF4349, Domain of unknown function (DUF4349). This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important.	2.97096e-73
NC_021171.1|WP_041580350.1|1253094_1253979_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.69452e-48
NC_021171.1|WP_015592967.1|1260430_1260643_-|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein	gnl|CDD|377805	pfam07288, DUF1447, Protein of unknown function (DUF1447). This family consists of several bacterial proteins of around 70 residues in length. The function of this family is unknown.	2.04469e-25
NC_021171.1|WP_015592963.1|1256236_1256779_+|peroxiredoxin	gnl|CDD|239313	cd03015, PRX_Typ2cys, Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. The functional unit of typical 2-cys PRX is a homodimer. A unique intermolecular redox-active disulfide center is utilized for its activity. Upon reaction with peroxides, its peroxidatic cysteine is oxidized into a sulfenic acid intermediate which is resolved by bonding with the resolving cysteine from the other subunit of the homodimer. This intermolecular disulfide bond is then reduced by thioredoxin, tryparedoxin or AhpF. Typical 2-cys PRXs, like 1-cys PRXs, form decamers which are stabilized by reduction of the active site cysteine. Typical 2-cys PRX interacts through beta strands at one edge of the monomer (B-type interface) to form the functional homodimer, and uses an A-type interface (similar to the dimeric interface in atypical 2-cys PRX and PRX5) at the opposite end of the monomer to form the stable decameric (pentamer of dimers) structure.	1.29801e-101
NC_021171.1|WP_015592972.1|1265679_1266657_+|alpha-ketoacid-dehydrogenase-subunit-beta	gnl|CDD|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NC_021171.1|WP_015592969.1|1262400_1262955_-|peptide-deformylase	gnl|CDD|234668	PRK00150, def, peptide deformylase; Reviewed.	3.39543e-67
NC_021171.1|WP_015592962.1|1254824_1255952_+|N-acetyldiaminopimelate-deacetylase	gnl|CDD|349920	cd05670, M20_Acy1_YkuR-like, M20 Peptidase aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins. Peptidase M20 family, aminoacyclase-1 YkuR-like subfamily including YkuR and Ama/HipO/HyuC proteins, most of which have not been well characterized to date. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity; substrates include indoleacetic acid (IAA) N-conjugates of amino acids, N-acetyl-L-amino acids and aminobenzoylglutamate. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as in the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). ACY1 appears to physically interact with Sphingosine kinase type 1 (SphK1) and may influence its physiological functions; SphK1 and its product sphingosine-1-phosphate have been shown to promote cell growth and inhibit apoptosis of tumor cells. Strong expression of the human gene and its mouse ortholog Acy1 in brain, liver, and kidney suggest a role of the enzyme in amino acid metabolism of these organs.	0
NC_021171.1|WP_015592959.1|1251522_1253040_+|MFS-transporter	gnl|CDD|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.00033e-66
NC_021171.1|WP_015592966.1|1258759_1260427_-|ribonuclease-J	gnl|CDD|223668	COG0595, COG0595, mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair].	0
NC_021171.1|WP_051120199.1|1263536_1264163_+|YkyA-family-protein	gnl|CDD|378419	pfam10368, YkyA, Putative cell-wall binding lipoprotein. YkyA is a family of proteins containing a lipoprotein signal and a hydrolase domain. It is similar to cell wall binding proteins and might also be recognisable by a host immune defense system. It is thus likely to belong to pathways important for pathogenicity.	3.06994e-54
NC_021171.1|WP_015592956.1|1249526_1250483_-|MBL-fold-metallo-hydrolase	gnl|CDD|293812	cd07726, ST1585-like_MBL-fold, uncharacterized subgroup which includes Sulfolobus tokodaii ST1585 protein; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Sulfolobus tokodaii ST1585 protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	8.09065e-101
NC_021171.1|WP_015592957.1|1250662_1250899_+|YkuJ-family-protein	gnl|CDD|370128	pfam08796, DUF1797, Protein of unknown function (DUF1797). This is a domain of unknown function. It forms a central anti-parallel beta sheet with flanking alpha helical regions.	7.49083e-28
NC_021171.1|WP_015592973.1|1266771_1268109_+|2-oxo-acid-dehydrogenase-subunit-E2	gnl|CDD|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	0
NC_021171.1|WP_015592974.1|1268112_1269522_+|dihydrolipoyl-dehydrogenase	gnl|CDD|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
NC_021171.1|WP_015592968.1|1261582_1262353_+|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|319819	cd07517, HAD_HPP, phosphatase, similar to Bacteroides thetaiotaomicron VPI-5482 BT4131 hexose phosphate phosphatase; belongs to the haloacid dehalogenase-like superfamily. Bacteroides thetaiotaomicron VPI-5482 BT4131 is a phosphatase with preference for hexose phosphates. In addition this family includes uncharacterized Bacillus subtilis YkrA, a putative phosphatase and uncharacterized Streptococcus pyogenes MGAS10394 a putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.25371e-105
NC_021171.1|WP_015592965.1|1257861_1258521_+|TrkA-family-potassium-uptake-protein	gnl|CDD|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	1.20331e-68
NC_021171.1|WP_015592971.1|1264563_1265676_+|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha	gnl|CDD|213783	TIGR03181, PDH_E1_alph_x, pyruvate dehydrogenase E1 component, alpha subunit. Members of this protein family are the alpha subunit of the E1 component of pyruvate dehydrogenase (PDH). This model represents one branch of a larger family that E1-alpha proteins from 2-oxoisovalerate dehydrogenase, acetoin dehydrogenase, another PDH clade, etc. [Energy metabolism, Pyruvate dehydrogenase].	0
NC_021171.1|WP_015592958.1|1251020_1251467_+|CBS-domain-containing-protein	gnl|CDD|341400	cd04643, CBS_pair_bac, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.37915e-65
NC_021171.1|WP_015592961.1|1254046_1254757_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	gnl|CDD|132571	TIGR03532, DapD_Ac, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase. This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. Alternate name: tetrahydrodipicolinate N-acetyltransferase. Note that IUBMB lists this alternate name as the accepted name. Unfortunately, the related succinyl transferase acting on the same substrate (EC:2.3.1.117, TIGR00695) uses the opposite standard. We have decided to give these two enzymes names which more clearly indicated that they act on the same substrate.	4.18413e-124

Protein sequences

>NC_021171.1|WP_015592965.1|1257861_1258521_+|TrkA-family-potassium-uptake-protein
MKKEFAVIGLGRFGGSICRTLAEQGMEVLAIDSDEDLVNEFSTIASHAVVADSTDENVLKSLGLRNFDHVIVAIGDDIKSSILTTLILIELGVKNITVKAQDDYHEKVLRKIGADHVVHPERDMGRRIANNISSNNVLDYLELSEEHSIVEIVANGKLGGHSIIDLDIRAKYGINIVAIKRGKNIIVSPQANEVIQADDVLIVIGADVDINRFEKKATH
>NC_021171.1|WP_015592964.1|1256909_1257791_+|DUF4349-domain-containing-protein
MFIKRYLPFLIFIMLLLSACSGNTQEKKSLGSNEVQQSDSVTSSKAQSKNEKDVPPINAKGNQTTSPNQKVIYTADLQLEVKDLKKANKLLEQAVKNVEGYIIQSNIYQDSDQTYHASLTIRVPQGSFEQFLDQAERLAVKVEQRNVSGSDVSEEYVDLESRLKSKRAVESRLLDFMQKATTTEDLLKISTDLATVQEQIEQITGRIKYLDNQVDFSTITIALSENKISVPALEKTDLNTIEKTKKQFMTSINWILITLSGVAVLIFGNIPILLVVGLIIGVVFFFLRRKKRA
>NC_021171.1|WP_015592963.1|1256236_1256779_+|peroxiredoxin
MSERLVGKQAPRFEMDAVLPNKEFGKVSLEENMKNDKWTVLFFYPMDFTFVCPTEIVAVSERYSEFEDLDAEVIGVSTDTIHTHLAWINTDRKDNGLGELKYPLAADHNHLVARDYGVLIEEEGIALRGLFIISPEGELMYAVVHHNNIGRDVDETLRVLQALQTGGLCPANWRPGQATL
>NC_021171.1|WP_015592962.1|1254824_1255952_+|N-acetyldiaminopimelate-deacetylase
MTLHPFVEIRRELHQIPELGFQEFKTQKYLLDYLNTLPKERIEIRTWETGLVVRVKGSSANKTIAYRTDIDGLPISEETELPFHSQHPGNMHACGHDFHMSIALGVLTHFVENQIDDHLVFIFQPAEEGPGGAEPMLNSNVLDGWEPDMIMALHIAPEYPVGTIAVKPGLLFANTSELFIDLKGKGGHAAYPHQTIDMVLAACTLVTQLQSVVSRNVDPLDSAVITIGKIAGGTVQNIIAERARLEGTIRTLSAESMEKVQARVQAIVNGIEVGFQCQAKVDFGAMYYQVYNHHELTLEFMDFVANHTDMKVVECKEAMTGEDFGYMLKDIPGFMFWLGVESEYGLHHSKLLPNEKAIEEGIAGIINYINFKGNR
>NC_021171.1|WP_015592961.1|1254046_1254757_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase
MKMMDANEIISFIQNSKKSTPVKVYLKGDLDDINFGENARTFINGNSGVVFGEWSEINEVIESNQAKIEDYIVEDDRRNSAIPLLNTKNIKARIEPGAIIRDHVEIGDNAVIMMGAVINIGAVIGEESMIDMNAVLGGRATVGKKCHVGAGAVLAGVIEPPSAQPVILEDNVLIGANAVVLEGVRIGEGAVVAAGAVVIEDVAPHTVVAGTPAREIKKIDEKTKSKTEIIQGLRQL
>NC_021171.1|WP_041580350.1|1253094_1253979_+|LysR-family-transcriptional-regulator
MSSLSEFHFLSVLAQEMNMRKAAERLFVSQPALSQRLQTIEKEWGTRLFIRSQKGLTLTPAGEIVITFVNEVLDKEDNVRESIHALNSKVHGTLKIAVASIVGQNWLPQVLKKFVNRYPQAKISLITGWSSEILKSIYEGQVHIGIIRGTPDWKGIKMHLFEDNLFLVDTEITQPEQVLETDRPFIQFKSDSNYYQEIHNWWHRQFQTVPKRTVVVDQIETCKQMAFNGIGYTILPGITLKNSEKDIFKIPLMNENGEPLKRDTWLLGYESAFKLKQVQVFVELIQEHLLESKQ
>NC_021171.1|WP_015592959.1|1251522_1253040_+|MFS-transporter
MEDAYKEQWAKKTVQKQTKRPLVLAAIMLAMFMGAIEATIVSTAMPDIVSDLGGFSLYSWVFSGYLLMNSVTVLIYGKLSDLFGRKPILTFGIIFFLIGSILCGFANSMKMLILFRFIQGFGAGAVMPIATTIVGDIYSTEERAKVQGYLASVWGISAVSGPVLGGFLVQFVSWRFVFWINIPLGLLSLVGLWMFLHEKIEKRKREIDYFGAGLLSIAIFTLMIVLVQGGTNWKWSSMPAISFFGVSMLAILLFVWQEKRSAEPVMPFSIWKERSILIANVASLITGVMLIGISSFLPAFVQGVMEQSPIVAGFTLTTMSIGWPIASTASGKLMIKYGFRNTSIIGGVSLILGSIMFIALTPELGPLWAAVGSFFIGIGMGLTSTAFIVLIQSTVGWEQRGIATAANMFMRNLGNTVGAALLGGILNSQLYAHLKSSPATEKMTIDSVNILLNENERNHLSLKVRLILQEGLTSALHSVYLVVFLLATSSFILVMFLPKKATANE
>NC_021171.1|WP_015592958.1|1251020_1251467_+|CBS-domain-containing-protein
MIRLQGGGFSEYTVKDLMIPSERVAHVQIGNNLEHALLVLTKSGYSAIPVLDPTYKLHGLISTPIIMEAILGLERIEFEKLEQIRVEEIMIKDTPTLTIESSPQSSLSLLVDHPFLCVEDGHGVFEGILTRRAVLLQLNKFVQIISKK
>NC_021171.1|WP_015592957.1|1250662_1250899_+|YkuJ-family-protein
MSQLQGILTRLKNLQDQANGGEPAQRFFEVNGERKCQVTYNPKTATYELEVYNEKEKPKRYQFDNVDMIAIEIFDLIQ
>NC_021171.1|WP_015592956.1|1249526_1250483_-|MBL-fold-metallo-hydrolase
MSKPVKLGENFYLIDDYDLKQPDRTGTYVLVEEELTIIETSASPSIPYLLQGLKDLQISPIDIKYIIVTHIHLDHAGGAGLMLEHCPNAKVIVHPKGERHLADPSRLIAGAQAVYGEKFSELFDPILPIPSDRLISMHDQSKLKISPKCTLRFFDTPGHANHHLSIYYPNVNGMFSGDTVGVFYPQLYRDGIELYLPSTSPNQFDPDKMRNSISMFENMNLDSIYFGHFGMSRSPQEVYRQVRLWLNIFIDAARLAFQEHTQFNDRVQLTEQILSQKISEYLTSNGISSDHPVYEVLTIDINVCSMGLIDYLERQARK
>NC_021171.1|WP_015592966.1|1258759_1260427_-|ribonuclease-J
MKFVKNDQTAVFALGGLGEIGKNTYGVQFQDEIILIDAGIKFPEDELLGIDYVIPDYSYLIKNEDKIKGLFVTHGHEDHIGGIPYLLREINIPIYGGKLALALIKNKLEEHGLLRNAKLYEIKEEEIIKFRKTSVSFFRTTHSIPDSYGIVVKTPPGQVVHTGDFKFDFTPVGEPANLTKMAEIGKEGVLCLLSDSTNSEIPNFTMSERRVGESIHDVFRKVDGRVIFATFASNIHRLQQVIEAAVLNGRKVAVFGRSMEAAIEIGLDLGYIRAPKETFIDAQQINRIPANKVTILCTGSQGEPMAALSRIASGTHRQIQIIPGDTVVFSSSPIPGNTISVSRTINMLFKAGADVIHGPLSDIHTSGHGGQEEQKLMLRLIKPKFFMPIHGEYRMQRMHAKLAVDCGVAEENCFLMDNGEVLALSDSSAQVAGKIPSGSVYIDGSGIGDIGNIVLRDRRILSEEGLVIVVVSINMKDFKVAAGPDIISRGFVYMRESSDLINDAQVLITKHLGKVMERKTTQWSEIKNEIADTLSPFLYEKTKRRPMILPIIMEV
>NC_021171.1|WP_015592967.1|1260430_1260643_-|DNA-dependent-RNA-polymerase-auxiliary-subunit-epsilon-family-protein
MIFKVYYQESSKQVAVRENTKTLYLEAESELDVRKKLAHKAFNIEYVQAVKGAFLEYEQKNEDYKVLEIE
>NC_021171.1|WP_015592968.1|1261582_1262353_+|Cof-type-HAD-IIB-family-hydrolase
MSKIVFFDIDGTLLDHEKKLPVKTKEAVKQLKENGVFVAIATGRAPFMFEQLRNELDIDSYVSYNGQYVVFENEVIYTNPLHTDELDRLHSNANSYGHPIVFMNEKTMKSNVPHHYYIEKSMDSLKLAHPEQDATFYHNKDILQSLLFVEEKEEHLYSDEYPHFQFVRWHPYSVDVLPKGGSKAEGIKKLIDRLGFKIEDVYAFGDGLNDMEMLQAVGTAVAMGNAVSELKQHATLITKDVDQDGIWHGLKELELI
>NC_021171.1|WP_015592969.1|1262400_1262955_-|peptide-deformylase
MLTMEDIIRDGHPTLRQIAEAVPIPASEEDKKILADLLEFVQNSQNPEIANQYGLRPGIGLAAPQINIAKRMIAIHVRDEKGELFSYALFNPKIVSHSVENSFLSSGEGCLSVDDPFPGYVPRHARITVKAIDLDGKEVKLRLKGLPSVVFQHEIDHLNGIMFYDYINKQDPYHHPENAIEIER
>NC_021171.1|WP_041580352.1|1263135_1263282_-|YjcZ-family-sporulation-protein
MFGYGGYGYGGCGVGYGGCGYPVGGFRGGFALIVVLFILLIIVGSAFC
>NC_021171.1|WP_051120199.1|1263536_1264163_+|YkyA-family-protein
MVSFSLTGCFGQKTPVEKMFTVMENVVDEEKGFEEQQKPLVELEQKEKDLYEKIISLGSKENDQIVKLSDEAISVVLEREKHMEKEQKSLIASKKKFETISPFITKLDDSDLKNRANDLYELMNKRYEIHDLLYENYMLGTQYDIELYKMLKDKEASMEQLDNQVTKINETYDKVLKANEQFNQQTKKYNETKLNFYKKAGIKVSEAK
>NC_021171.1|WP_015592971.1|1264563_1265676_+|pyruvate-dehydrogenase-(acetyl-transferring)-E1-component-subunit-alpha
MKSNTKTQLDIKKQFEIVEEQFQTLQILNEEGQVVNESAMPELSDEQLQELMSRMVYTRILDQRSISLNRQGRLGFYAPTAGQEASQLASQFALEKEDFILPGYRDVPQLIWHGLPLFQAFLWSRGHMEGMNVPEGVNVLHPQIIIGAQYVQTAGVALGMKKRGAKSVAITYTGDGGTSQGDFYEGMNFAGAFKAPAIFIVQNNRFAISTPVNKQSATKTLAQKAVAAGIPGIQVDGMDPLAVYVATHDARLRAINGDGPTLIETLTYRYGPHTMAGDDPTRYRTADLDNEWEKKDPLVRFRKFLENKGIWNEEKESEVIEKAKEDIKEAIKKADAASKQKVTDLMSIMYEEMPSNLKEQYEIYKAKESK
>NC_021171.1|WP_015592972.1|1265679_1266657_+|alpha-ketoacid-dehydrogenase-subunit-beta
MAQLTMIQAITDALRSELRNDPNVLVFGEDVGVNGGVFRATENLQKEFGEERVFDTPLAESAIGGLAVGLSLQGFRPVPEIQFFGFVFEVMDSISGQLARMRYRSGGRYNAPVTIRSPFGGGVHTPDMHADSLEGLMAQQPGLKVVIPSTPYDAKGLLIASIRDNDPVIFLEHMKLYRSFRQEVPEEAYTIPLGKADVKREGSDLTIVTYGAMVHESLKAAEELAKEGHSIEVIDLRTVSPIDIETIIASVEKTGRAIVVQEAQKQAGISAHVVAEINDRAILSLEAPVLRVTAPDTVFPFPQAESVWLPNYKDVIETAKKVLSF
>NC_021171.1|WP_015592973.1|1266771_1268109_+|2-oxo-acid-dehydrogenase-subunit-E2
MAFQFRLPDIGEGIHEGEIVKWFVKPGDKIQEDDVLCEVQNDKAVVEIPSPVAGTVEEVLIGEGTVATVGQVLVTFDAPGYEDIQFKGDHEEDTKEEVKVEVPVAPITASTPAVVETPTQASPVAVAKSQAEVDPNRRIIAMPSVRKYARDNGVDIRLVSGTGKNGRILKENIDAFSAGGAAVVSIAQEQQVENQVVQPEKAATISAIPQGQYPETREKMSGIRKAIAKAMVNSKHTAPHVTLMDEIDVTKLVANRKKFKEVAAQKGIKLTFLPYVVKALTSALREFPALNTSLDDAVGEIVHKHYYNIGIAADTEKGLLVPVVKDADRKSIFNISNEINELATKARDGKLAPDEMKGASCTISNIGSAGGQWFTPVINHPEVAILGIGRIAEKPIVRGGEIVVAPVLSLSLSFDHRMIDGATAQNALNHIKKLLNDPELLLMEA
>NC_021171.1|WP_015592974.1|1268112_1269522_+|dihydrolipoyl-dehydrogenase
MVVGDFPIETDTIVIGAGPGGYVAAIRAAQLGQKVTIVEKGAVGGVCLNVGCIPSKALIAAGHKYETAIHSESIGITAENVKVDFTKVQEWKAGVVKKLTGGVEGLLKGNKVNIVRGEAYFVDANTLRVMDENSAQTYTFNHAIIATGSRPIELPAFKYSKRVLDSTGALALPEIPKKIVVIGGGYIGTELGGAYANFGTQVTILEGTDEILNGFETQMSSIVKKNLKKKGADIITNALAKGVVETENSVTIKYEVKGEEKAVEADYVFVMVGRRPNTDELGIEQVGIEMTDRGVIKIDKQCRTSVGNIYAIGDIVPGPPLAHKASYEAKIAAEAIAGLQTEIDYLGIPAVVFSDPELASVGYTEKQAKEEGLEVNASKFPFAANGRALALDATDGFLKLVTRKADGLVIGAQIAGSSASDMIAELGLAIEAGMTAEDLAMTIHAHPTLGEITMEAAEVAIGHPIHIVK

Crispr_ID: NC_021171_3

• CRISPR_ID: NC_021171_3
• CRISPR_location: 1743341-1743414
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021171_3

Consensus_repeat	Method
TCTGGACATTGAGTTCGTTATTT	CRISPRCasFinder

spacers of NC_021171_3

>3.1|1743364|28|NC_021171|CRISPRCasFinder
TAAGAATAAACGCTATTTTGAGAATATG

CRISPR arrays and Neighbor proteins around NC_021171_3

CRISPR arrays

The CRISPR arrays of NC_021171_3

>merge|NC_021171|3|1743341-1743414|CRISPRCasFinder
TCTGGACATTGAGTTCGTTATTTTAAGAATAAACGCTATTTTGAGAATATGTCCGGACATTGAGTTCGTTATTT

>NC_021171|3|3|1743341-1743414|CRISPRCasFinder
TCTGGACATTGAGTTCGTTATTT	TAAGAATAAACGCTATTTTGAGAATATG
TCCGGACATTGAGTTCGTTATTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_015593405.1|1731348_1732497_+|sulfate-adenylyltransferase	unknown	unknown	gnl|CDD|235227
NC_021171.1|WP_041580976.1|1743689_1744313_+|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl|CDD|131955
NC_021171.1|WP_015593418.1|1748622_1749870_+|MFS-transporter	unknown	unknown	gnl|CDD|340883
NC_021171.1|WP_015593407.1|1733140_1734760_+|hypothetical-protein	unknown	unknown	gnl|CDD|236572
NC_021171.1|WP_015593413.1|1740012_1743267_+|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015593421.1|1752944_1753949_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|378117
NC_021171.1|WP_015593419.1|1749967_1750201_+|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015593423.1|1754247_1755015_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
NC_021171.1|WP_015593410.1|1736242_1737559_+|response-regulator	unknown	unknown	gnl|CDD|226229
NC_021171.1|WP_015593406.1|1732523_1733123_+|adenylyl-sulfate-kinase	unknown	unknown	gnl|CDD|179661
NC_021171.1|WP_015593415.1|1744588_1745641_-|M42-family-metallopeptidase	unknown	unknown	gnl|CDD|349907
NC_021171.1|WP_051120204.1|1738603_1740016_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133045
NC_021171.1|WP_015593422.1|1753960_1754251_+|thiamine-binding-protein	unknown	unknown	gnl|CDD|376658
NC_021171.1|WP_015593417.1|1746504_1748442_+|LTA-synthase-family-protein	unknown	unknown	gnl|CDD|224287
NC_021171.1|WP_015593420.1|1750292_1752509_-|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl|CDD|236645
NC_021171.1|WP_015593408.1|1734855_1735071_+|DUF3906-family-protein	unknown	unknown	gnl|CDD|289791
NC_021171.1|WP_015593411.1|1737559_1738600_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|379311
NC_021171.1|WP_015593409.1|1735099_1735831_+|sirohydrochlorin-chelatase	unknown	unknown	gnl|CDD|225049
NC_021171.1|WP_015593416.1|1745841_1746144_+|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_041580399.1|1730193_1731273_+|inorganic-phosphate-transporter	unknown	unknown	gnl|CDD|223383

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_015593405.1|1731348_1732497_+|sulfate-adenylyltransferase	gnl|CDD|235227	PRK04149, sat, sulfate adenylyltransferase; Reviewed.	0
NC_021171.1|WP_041580976.1|1743689_1744313_+|LysM-peptidoglycan-binding-domain-containing-protein	gnl|CDD|131955	TIGR02909, conserved_hypothetical_protein, uncharacterized protein, YkwD family. Members of this protein family represent a subset of those belonging to pfam00188 (SCP-like extracellular protein). Based on currently cuttoffs for this model, all member proteins are found in Bacteria capable of endospore formation. Members include a named but uncharacterized protein, YkwD of Bacillus subtilis. Only the C-terminal region is well-conserved and is included in the seed alignment for this model. Three members of this family have an N-terminal domain homologous to the spore coat assembly protein SafA.	4.68471e-62
NC_021171.1|WP_015593418.1|1748622_1749870_+|MFS-transporter	gnl|CDD|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.33355e-18
NC_021171.1|WP_015593407.1|1733140_1734760_+|hypothetical-protein	gnl|CDD|236572	PRK09566, nirA, ferredoxin-nitrite reductase; Reviewed.	1.56601e-172
NC_021171.1|WP_015593421.1|1752944_1753949_+|ABC-transporter-substrate-binding-protein	gnl|CDD|378117	pfam09084, NMT1, NMT1/THI5 like. This family contains the NMT1 and THI5 proteins. These proteins are proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine. They are regulated by thiamine. The protein adopts a fold related to the periplasmic binding protein (PBP) family. Both pyridoxal-5'-phosphate (PLP) and an iron atom are bound to the protein suggesting numerous residues of the active site necessary for HMP-P biosynthesis. The yeast protein is a dimer and, although exceptionally using PLP as a substrate, has notable similarities with enzymes dependent on this molecule as a cofactor.	1.72772e-92
NC_021171.1|WP_015593423.1|1754247_1755015_+|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.58475e-59
NC_021171.1|WP_015593410.1|1736242_1737559_+|response-regulator	gnl|CDD|226229	COG3706, PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms].	8.13513e-47
NC_021171.1|WP_015593406.1|1732523_1733123_+|adenylyl-sulfate-kinase	gnl|CDD|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	6.16837e-123
NC_021171.1|WP_015593415.1|1744588_1745641_-|M42-family-metallopeptidase	gnl|CDD|349907	cd05657, M42_glucanase_like, M42 Peptidase, endoglucanase-like subfamily. Peptidase M42 family, glucanase (endo-1,4-beta-glucanase or endoglucanase)-like subfamily. Proteins in this subfamily are co-catalytic metallopeptidases, found in archaea and bacteria. They show similarity to cellulase and endo-1,4-beta-glucanase (endoglucanase) which typically bind two zinc or cobalt atoms. Some of the enzymes exhibit typical aminopeptidase specificity, whereas others are also capable of N-terminal deblocking activity, i.e. hydrolyzing acylated N-terminal residues. Many of these enzymes are assembled either as tetrahedral dodecamers or as octahedral tetracosameric structures, with the active site located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers.	2.17054e-173
NC_021171.1|WP_051120204.1|1738603_1740016_+|glycosyltransferase-family-2-protein	gnl|CDD|133045	cd06423, CESA_like, CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.	3.30455e-62
NC_021171.1|WP_015593422.1|1753960_1754251_+|thiamine-binding-protein	gnl|CDD|376658	pfam01910, Thiamine_BP, Thiamine-binding protein. The crystal structure of two of these members shows that this domain has a ferredoxin like fold and is likely to exists as at least homodimers. Sulphate ions are are located at the dimer interfaces, which are thought to confer additional stability. Although the function of this domain remains to be identified, its structure suggests a role in protein-protein interactions possibly regulated by the binding of small-molecule ligands. Solution of the structure of the hyperthermophilic anaerobic Thermotoga maritima sequence, UniProtKB:Q9WYV6, shows that this has a beta-alpha-beta-beta-alpha-beta ferredoxin-like fold and assembles as a homotetramer. It was possible to identify a pocket in each monmer that bound an unidentified ligand. It was also found that it bound charged thiamine though not hydroxymethyl pyrimidine. It is proposed that it is transporting charged thiamine around the cytoplasm. Under oxidative conditions this bacterium is under stress, and the transcriiptional unit within which this protein is expressed is up-regulated in these conditions, suggesting that the chelation of cytoplasmic thaimine is part of the response mechanism to such oxidatvie stress, which is mediated by this family.	1.90832e-24
NC_021171.1|WP_015593417.1|1746504_1748442_+|LTA-synthase-family-protein	gnl|CDD|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NC_021171.1|WP_015593420.1|1750292_1752509_-|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl|CDD|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	4.9393e-119
NC_021171.1|WP_015593408.1|1734855_1735071_+|DUF3906-family-protein	gnl|CDD|289791	pfam13046, DUF3906, Protein of unknown function (DUF3906). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 70 amino acids in length. There is a conserved EKK sequence motif.	3.10412e-27
NC_021171.1|WP_015593411.1|1737559_1738600_+|HEAT-repeat-domain-containing-protein	gnl|CDD|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	0.000691931
NC_021171.1|WP_015593409.1|1735099_1735831_+|sirohydrochlorin-chelatase	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	1.97658e-54
NC_021171.1|WP_041580399.1|1730193_1731273_+|inorganic-phosphate-transporter	gnl|CDD|223383	COG0306, PitA, Phosphate/sulphate permeases [Inorganic ion transport and metabolism].	2.85923e-60

Protein sequences

>NC_021171.1|WP_015593413.1|1740012_1743267_+|hypothetical-protein
MKKILTKGQTILYIYLLVFLLIITSPFWIWFLKESKSLDVLIVDKTVPNKSYREHEGFVWLLNNEKLTQKNNQPYSASKDYVGFKFDKNKTFKKEGLPKDLNPYKLIYLTDQYGVYKEEFHKKNQSGKRSEQIYGGLTNQEVDQLDKTLLKGGKTLIAEFNTFASPTSEEVKEKVSNLLNITWSGWIGRYFSDLDLGGAEVPVWVKENYEKDNGKWDFSGKGIVLVDRNDFIVVLDSKDLKNSGAVFNLTKKGNKLYEVDRNIPYQYWFDIIEARNSDEVLANYNLPVKASGQEKLDRYGLPNQFPAIVYHQNRKYSSYYFAGDYADEPEVPAIYQSEFISFWKKNITTLPSFYWKAYVPVMKQILKTGLQPQIEQKEIVETKKENGVTTNGKTTKKYIQVLKDGKWEDLLIKGVNIGIAKPGYFPGETAISKTEYLRWFQAIGEMNANTIRIYTLHPPEFYQAFYEYNKTAKKPLYLLHGAWVNEEKLVSSQDAFSSETTEDFQKEIKKIIDVIHGNATIPEEKGHASGTYSYDISPYVLGIIAGIEWDPEAVLHTDEKNQDKASYAGTYFKTNDATPFESWLARMLDFTTTYETDKYKWQHSLSFTNWVTTDLLDHPAEPLESEDLVSVNPNHIEKTDRFLAGLFASYHVYPYYPDALNSDQKYMNYIDYQGKKNNYAGYLHELIQAHHLPVLVAEFGVPASRGLTHKNVHGMDQGFHSEKEQGQINKHLYESIVSEGYAGGLVFSWQDEWFKRTWNTMEYDDANRRPYWSNLQTNEQHFGLLSFDPGKLGKSIIMDGNTGDWEQNGVKPIYTSEKKGLISNVFVHSDEGYLYVRLDYSRNIDWNMNTSYLLLDTIADQGQQNIQMKNKQTVQTNNGVDFIVSLAGEKDSNIMIDSNYDTFYYQYGHLLHMIPEESNANQKNNGVFNPIRLALNKKLDVPDKGIHIKFQDYVTGKLLFGNGNPLSSKYKSLIDVSMSKDKKVLELRIPWQLLNVKDPSQRLIMSDFWRNGIEGEQKTDGVKIAVLATEKDQTIASFPEVVNGQMNGADSYLFQWKEWEQPNYHERLKASYYIMKEAYKSSKK
>NC_021171.1|WP_051120204.1|1738603_1740016_+|glycosyltransferase-family-2-protein
MGTLFLHGFAVYFAFFIVIYMAIVICFYSIIFFISMLQLRKEYKLNRNQPFQEYMNDLNVKPLSILVPAFNEEPGIVHSIRSLLSINYPRYEIIVINDGSTDKTLQKVIEHYEMIEIERVVRKQIDTAPIKKIYQSTILPELYLIDKENGGKADALNIGLNFSHYPYFCSLDGDSILERDAFLKVMKPIMDSNGEVIASGGSIRIANGCDIQSGHMVRIGLPNNPLVMMQIIEYLRAFLMGRIGLSKYNLLLIISGAFGVFSKSWVIQAGGYNPNTVGEDMELIVRVHRLLKERGEKKRIVYIPDPVCWTEVPETMKYLRRQRRRWHRGLLESLWTHRKLTFNPKYGSIGLISFSYFWIIEFFGPVVELSGYIYIIVSLFTGGVYVEFAILIFLLSCLYGSLFSMTAVLLEEWSLRKYPKISQIIILFLYSLTETIWYRPLTVLWRVEGIWQMLTGDRSWGEMKRKGVSQ
>NC_021171.1|WP_015593411.1|1737559_1738600_+|HEAT-repeat-domain-containing-protein
MVHKEIYLLMKASLIILVLLFILLFYLVIRKAIENNRRNGIEVLKEEMNQWLYQYLVEGNLVRALKPDTFVKKVALEELLVRYTEILEGDVEKSRISILADQHLMEYYQRNLKSLIWSQRMNALFHIEGFELKSLINEVIERLENARSSQEEVLLSLRILASFGYQNIFQLLQLKWDKLTEFDYRSILYRLNIDFLGQFISGFRQCPEQLKYAILEVISTKKEPRYSLFLETTFTKGEGEIRIRALKAIASMGFVLNIDPYLTLSNSNVWQERMMAAKLFGNSQENETIPYLTRMLSDRNWWVRFQAGQAIMMFPNGHEILHEIHDVSEDSFARDMAREWMNKGAI
>NC_021171.1|WP_015593410.1|1736242_1737559_+|response-regulator
MTQSEKYQQMLIQIIEDDLPGLILLKKALEEKGWMVIADTDPEKATDHYFELNPDCLILNAKLPTKNGFQILEEIQEHNGRLFIPKIILSSRNDKETRLDAFKTGADDFIEKPYDIEELLIRIENHLHRKQIYDQSVLIDTLTQVYNRKYLHIDLEKSIKEWKRTNDSLTIAIIDFDNFAFLNKRYGHLSGDSILSEFAQFIKQSIRSGDTVYRIRGDQFLIQFPRAGDLEVKEVINRLLSDFSYKSFEKDGQYFSVTFSAGVFELYDDDIPAKTAIQMADKALTKAKEAGKARVEIIKETSVTFVKKRLVISIIDHDMIMRTMLMKIFQSLVLDSSELSIEAFEDGNKFFQSNRLEEQGKHFLVFEGVMPVMNGIEILQKIKKNSNRPQMRILMLAGKKDENEIARALKFGADDYMTKPFSITELKARIERLIQRMM
>NC_021171.1|WP_015593409.1|1735099_1735831_+|sirohydrochlorin-chelatase
MEAVLYICHGSRVKQAQEQAVSFIQSCMEEINAPIQEYCFLELATPSIETAFRKCINRGATKIIAVPVLLLTAGHAKEDIPSELSRINSIFPTITVEYSQPIGVHPDIIEILIERIKETKHELTAEESMILLVGRGSGDPQVKVDLSRIAEMLSERSGTKKVDVCFLAASNPSFEEGFEKAKESGFKQVFIIPYLLFTGILMRKIEKMIQTEPKLDQEMILCSYLGYHPLLKKILKDRVKEHI
>NC_021171.1|WP_015593408.1|1734855_1735071_+|DUF3906-family-protein
MNLYRFEVTIGSEVAHVIVAAENDEAAFRQVDIEIETHFLKLPVVNDVVLYERKIIRKGAGFVISRNETII
>NC_021171.1|WP_015593407.1|1733140_1734760_+|hypothetical-protein
MAYEKIWADNPVLNKTELRKLQKDALRIFDDIPYYAQNGFSSIPTEEWDMFKWAGLYLQKPKEDGYFMMRVCVPSGVLTNEQAIVLANIAKDYGRGVYDFTTRQAIQFHWLTIDQIPDIYSRLESVGLSTAGACGDITRNIVGNSLAGIDPNELFDTRPIVKEVYDFFQFNEDFSNLPRKFKISISSNVNNASNSEINCLSFVPAYKEINGERVAGFNVKVGGGLSAVPYLAETLDIFVTTDKTLEVAIAITTLYRDHGYREKRHRARLKFLIADWGVEKFKEKLIELTGPLPEKGEDAQKDWNAGYFYGVHQQKQAGLNYIGANIPVGRLTPEDVIEFARISKKYGDGEIRNCNSQNIVIPNIPDENVDAILKEAIFTKFPIAPNKIVGYAVSCTGSEYCNLALVETKNRMKTIAEQLDEEISLDVPVRIHMVGCPNSCGQRNIADLGLHGVKSRNQDKKLVEAFEIYVGGTLNKEAKFNEKLKGKVEADHLKQVVKELLQSFQDTKLPGELYADYVNRVGKDFIQEKLDSILSSVTV
>NC_021171.1|WP_015593406.1|1732523_1733123_+|adenylyl-sulfate-kinase
MGKSSNITWHELSLSKESRRKQNGHQSFVLWFTGLSGSGKSTVANALAQKLFELDIRNYVLDGDNVRHGLNKDLGFSDSDRTENIRRIGEVSKLFVDSGQVVLTAFISPFLADRQLVRSLLEDDEFIEIYVKCPIEECENRDPKGLYDKARKGLIPDFTGIHSPYEEPLQPEIVVDTNESSVAECVEQIVNYLSSKNAI
>NC_021171.1|WP_015593405.1|1731348_1732497_+|sulfate-adenylyltransferase
MALSTPHGGSLINRWNPEYDFESIKQEIVIDNMALSDLELIATGAYSPIEGFFSKEDYESVVKNMRLANGSVWSIPITLPVSVEQAQSVTIGEEYRLVYNGETYGVISVSDIFEPNKEVEAELVYRTTDVAHPGVKKLFDRGNIYIGGKITLVKRLERKQFQSYYLDPVETRVIFEEKGWKTVVGFQTRNPVHRAHEYIQKTALETVDGLFLNPLVGETKSDDIPADVRMESYEILLKNYYPEERVYLAVFPAAMRYAGPREAIFHAMVRKNYGCTHFIVGRDHAGVGDYYGTYDAQTIFNNFTEDELGISLLFFEHSFYCSKCENMASTKTCPHGKEYHAILSGTKVRELLRNGEIPPSTFSRKEVVEVLIKGLREHALKA
>NC_021171.1|WP_041580399.1|1730193_1731273_+|inorganic-phosphate-transporter
MTLTYLAGAVALFFAMNIGASGAAASVSVAYGSGAISNRKKALLLCGIAIFVGAVLGGSEVTKTIGSNIIPQSFLNAKVVLIILSSAAISLFIANLIGIPLSTSEITVGSVVGVGVAYKALFINNILVIVSFWIIIPAIAFVIAIILGKGIHRLEKRYPVLSKDKYKPILSIFVIIVGFLEAFSAGMNNVANAAGPMVGAGLISIKTGIVVGGFFIALGAITLGGRVLETNGKKITKFSLLEGGAVSGTGATLVILASIFGLPVPLTQVTSTAIIGISTVQQGAGALKKNIISKILKVWLVSPILSLVISYGLIKLFVESDMYSVVVLFSVCTATLGIISLLKTIRADARTIYEDGGGI
>NC_021171.1|WP_041580976.1|1743689_1744313_+|LysM-peptidoglycan-binding-domain-containing-protein
MIKKIVLSVFVMFMSMPIFSQAAIQMFKEPPFEFYKVSSGDSFWFIAQRYGLDYKQLMALNPGVDPMNMHVGEVIRLKSSAASPSGFEDQVAQLVNSERAKNGLKPLTHRADLKSVAEKKAQDMINSNYFSHTSPNYGSPFDMMKTFGISYSSAGENIAKGQTTPQEVMNSWMNSSGHRANILNSSYNCIGVGFYHGAWVQMFIQSR
>NC_021171.1|WP_015593415.1|1744588_1745641_-|M42-family-metallopeptidase
MSIYPNTDETIVILKDLVSIPSPSGNTNEVITYVEEYLQKQGISGYRNKKGGLIVTLPGQDDSRHRMLTAHVDTLGAMVKEVKDSGRLKLDLIGGFKFNSIEGEYCKIHSSTGKVYTGTILLHQTSVHVYKDSDKLERNQDNMEIRIDEVVKNSEDVTKLGIEVGDFISFEPRVEITPSGFIKSRHLDDKASVAILLQLIKQINEQSVSLPYTTHILISNNEEIGYGGNSNISPETVEYLAVDMGAIGDGQATDEYTVSICVKDASGPYHLELRKRLIQIAQENGIDYKLDIYPYYGSDASAAIRSGHDIVHGLIGPGIDSSHAFERTHKTSIENTAKLLYHYVQSEMTR
>NC_021171.1|WP_015593416.1|1745841_1746144_+|hypothetical-protein
MSRSERNQTQVNPFLKIKIVFLIMLFVGLMVITNIYLNGIIRIETPEVDLGRKVVVHLEDGKEVQTYENLLVKKKGKLYYQGEFNTIDVTGGIVVFQDWD
>NC_021171.1|WP_015593417.1|1746504_1748442_+|LTA-synthase-family-protein
MKKLLGSPKKILSGSLSVFFLAVILFWLKTYAAYQIEFDLGIENKLQKFLLFINPISSSLLFLGIALLFRKRGQNVMLVFMNFILTFLLYANVVYYRFFNDFITVPVLLQTKTNSGQLGDSVLSLMSPWDVFYFTDTILLILFLVFKVVKPLKGNNRRPAAFVIAAAVIVFLFNLGLAEKDRPQLLSRSFDRNYLVKYLGTYNFTIYDMIQNAKSSSQRAMADSSDIVDVENYIKANYTAPNPEYFGKAKGMNVIYVSMESLQNFIIDYKIDGQEVTPFLNSIAHNGEAFYFKNVFHQTGQGKTSDAEFMMENSLFPMSQGAVFVNKAQNTYQAMPGILKGQNYTSAVFHGNYKTFWNRNEIYKAFGYDKFYDAEYYDMSEENTKNYGMKDVPFFEQSMPLLTGLKQPFYTKFITLSNHFPFKMDEGDTDFPAGEFGDDSVVNNYFQSAHYMDHALEMFFNDLKTSGLYDHTVVVLYGDHYGISENHNEAMANVVGKEINDFENAQLQRIPLFIHVPGVKGNIVDSYGGQVDVSPTVLHLLGTDTKDYMQIGSDLLSPQHQQTVAFRNGDFVSPEITHLGEKTYSNATGELVDGKQYKDQSDQANMKLKISDEIVYKDLLRFYTPQGFKKIDPKDYSYVKKTDTK
>NC_021171.1|WP_015593418.1|1748622_1749870_+|MFS-transporter
MSIPTINQLNEKYSIRNGIAQTIVLNGSNNYFILFAISVLGASNYQVGLINSLPQFIGMFGMLVGSVIMNKLPEKRKFTAYSFLFTRLFLLGMFFVVFIPREYSGWVFVLLVGFMNLPGSFANLSWQAFIGDLVPEKRRSGFFSQRNMMLTLVGMVVTFIIGIGLQFFSKTNPIPYQFLFLLTFIAGIFEVYYLLKHVESKKSNLAMKKSVKVGMVAFKDKRFVYFLICGLCFNFTWQMAWALFSIFQIKYAHATGFWISVITVANQIGQIVSYKWWGRMADKYGNAKMMIPVSLGMAAAPVLTILSKNMVYLTIINGLSGLFVSGTVLLLFNLLLEVTNKDNRDSFISQYNILLAIVGFIAPQFGVLLLEQASMSFAMITSTLLRISSGGLFIFLSIYLTKKPKNFHKITIKSS
>NC_021171.1|WP_015593419.1|1749967_1750201_+|hypothetical-protein
MGHCNLDHTHEDVLKKYESQTSFLPEETKPLFNAFFQKQHGQEILNEVFHLLKKYDLVSEEEQETRNQRILLVLRNV
>NC_021171.1|WP_015593420.1|1750292_1752509_-|bifunctional-diguanylate-cyclase/phosphodiesterase
MNQDESFYLIESKQQSHFNTNENDSNRHLSTDKLDDFCNIFPQNSLALSQLNEKIRYAVDQSINIVITNIDGYILYVNSSCYELIHYQPDELIGVHTKIFNAGYHSSEFFKEMWDTILSGKIWRGDVKNRKKDGDHVWVRMRIIPLLGESGTPHQFVALREDITEKKELEFQLALKDKQLSALTKYSYDAVGIIDHLGVITYQNPAIERVLGYKTTDTLGSNILMYLDEKEIVREKSFLKRFAKITDAPINRQLRIRHKNGTMRWCDVALTNYLDDPYIKGIVFNIRDVTKQKESSEVVNQIAYFDFLTGLPNRRHFEDLLKDTLQNAESSNRRVALLFLDLDGFKTINDTLGHEIGDGLLIKVAQRISSRFEKKAIIGRLGGDEFSIIIPNMFDFKYLHKFASSLVRIFNRPFNVEDFELNVSASIGISIYPLGGKDMKTLLKHADVAMYQAKKEGKNHYQLYSPSMDQNGYKAFLLKNDLKKALDEEQFFIVYQPRVNPNTHKLVGCEALIRWNHPIFGLVSPLEFIPYAEETYFIIPLGEWILTSVCTQAKDWQRQGLQPIKVSVNISAIQLLHPNFVKNVKNILKESGLEPEWLELEITETVLLNKEDQALKALEKLSSMGFTIALDDFGTGYSALNYLTKYKFDVIKIDRSILKNIPNDGESYEVANAIVRLAQTLKKKVVAEGIETSVQLALVAKMGCDEFQGYICSKPAEVDIFKKFLEDGKWNYKKNKEV
>NC_021171.1|WP_015593421.1|1752944_1753949_+|ABC-transporter-substrate-binding-protein
MKKWLVLLFAALLITGCSTSKKVDNAQQKKQDKQDALKKVTVVLDWTPNTNHTGLYVAKEKGYFKEQGLDVKIIMPGEAGADQLVASGKSQFGVGYQEGVTQARIQGVPLVSIAAVIQHNTSGFASPAEKNIKSPKDFTGKTYGGWGSPVEKSIIESLMKKENADVGKVKIVNIGDTDFFTAIKKDVDFSWIYYGWDGVEAELRGEKINMVYLTDYSDKLDYYTPVLTTNEKMISKNPETVRAFVKASAKGYEYAIKNPSDAADILIKAAPDLDPKLVKKSQEWLAPKYQDDATRWGEQKLEVWENYASWMFENGLLEKELDAKKAFTNEFLPK
>NC_021171.1|WP_015593422.1|1753960_1754251_+|thiamine-binding-protein
MANALVSIQILPKPADGGDVIPYVDEAIRIIQESGVKFEVHPLETTMEGELTHLFSIIEKMNERMMEIDCKNVISQIKVLYQPSGITMDTLTEKYR
>NC_021171.1|WP_015593423.1|1754247_1755015_+|ABC-transporter-permease
MKYFLRKGWRPIAVLLLLFVLWELIVAKAKIPVWLLPAPSKILSETISGWTMFYPDLLSTIQISIEGFMVGAVVGLVVAILLHLVPWIRDSVYPLLILSQNVPIIVLAPLLVIWFGFGLLPKIIVITLVCFFPITVATLDGLKQVPKGYKHYMLMAGANKSQLFWKLEWPYALPTIFSGLKISATYSVMGAVISEWLGAEKGIGVYMTLASSSFRTDKVFVAILAIMLLSLLFFSFIVVAEKYFIRWHGKGGNSE

Crispr_ID: NC_021171_4

• CRISPR_ID: NC_021171_4
• CRISPR_location: 2189080-2189589
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of NC_021171_4

Consensus_repeat	Method
TCGTTCAAGCCGCCGTTC	CRT

spacers of NC_021171_4

>4.1|2189098|66|NC_021171|CRT
AAGCCGCCGTTCAAGCCGCCGCTCAAGCCGCCGTTCAAGCCATCGTTCAAGCCGCCGTTCAAGCCA
>4.2|2189182|78|NC_021171|CRT
AAGCCGCCGTTCAGGCCGTCGTTCAGGCCGTCGTTCAAGCCGCCGTTCAAGCCGCCGTTCAGGCCGTCGTTCAGGCCG
>4.3|2189278|54|NC_021171|CRT
AAGCCGCCGTTCAGGCCGTCGTTCGAGCCGCCGTTCAGGCCGTCGTTCGAGCCG
>4.4|2189350|54|NC_021171|CRT
AAGCCGCCGTTCGAGCCGTCGTTCAAGTCGTCGTTCGAGCCGTCGCTCAGGTCG
>4.5|2189422|30|NC_021171|CRT
GAGCCGTCGTTCAAACCGCCGTTCGAGCCG
>4.6|2189470|18|NC_021171|CRT
GAGCCGTCGTTCAAGTCG
>4.7|2189506|30|NC_021171|CRT
AGGCCGTCGTTCGAGCCGTCGTTCAGGCCG
>4.8|2189554|18|NC_021171|CRT
AGGCCGTCGTTCGAGCCG

CRISPR arrays and Neighbor proteins around NC_021171_4

CRISPR arrays

The CRISPR arrays of NC_021171_4

>merge|NC_021171|4|2189080-2189589|CRT
ACGTTCAAGCCGCCGTTCAAGCCGCCGTTCAAGCCGCCGCTCAAGCCGCCGTTCAAGCCATCGTTCAAGCCGCCGTTCAAGCCATCGTTCAAGCCGCCGTTCAAGCCGCCGTTCAGGCCGTCGTTCAGGCCGTCGTTCAAGCCGCCGTTCAAGCCGCCGTTCAGGCCGTCGTTCAGGCCGTCGTTCAAGCCGCCGTTCAAGCCGCCGTTCAGGCCGTCGTTCGAGCCGCCGTTCAGGCCGTCGTTCGAGCCGTCGTTCAAGCCGCCGTTCAAGCCGCCGTTCGAGCCGTCGTTCAAGTCGTCGTTCGAGCCGTCGCTCAGGTCGTCGTTCAAGCCGCTGTTCGAGCCGTCGTTCAAACCGCCGTTCGAGCCGTCGTTCAAGCCGCCGTTCGAGCCGTCGTTCAAGTCGTCGTTCAAGCCGTCGTTCAGGCCGTCGTTCGAGCCGTCGTTCAGGCCGTCGTTCAAGCCGCCGTTCAGGCCGTCGTTCGAGCCGTCGTTCAAGCCGCAGATA

>NC_021171|4|1|2189080-2189589|CRT
ACGTTCAAGCCGCCGTTC	AAGCCGCCGTTCAAGCCGCCGCTCAAGCCGCCGTTCAAGCCATCGTTCAAGCCGCCGTTCAAGCCA
TCGTTCAAGCCGCCGTTC	AAGCCGCCGTTCAGGCCGTCGTTCAGGCCGTCGTTCAAGCCGCCGTTCAAGCCGCCGTTCAGGCCGTCGTTCAGGCCG
TCGTTCAAGCCGCCGTTC	AAGCCGCCGTTCAGGCCGTCGTTCGAGCCGCCGTTCAGGCCGTCGTTCGAGCCG
TCGTTCAAGCCGCCGTTC	AAGCCGCCGTTCGAGCCGTCGTTCAAGTCGTCGTTCGAGCCGTCGCTCAGGTCG
TCGTTCAAGCCGCTGTTC	GAGCCGTCGTTCAAACCGCCGTTCGAGCCG
TCGTTCAAGCCGCCGTTC	GAGCCGTCGTTCAAGTCG
TCGTTCAAGCCGTCGTTC	AGGCCGTCGTTCGAGCCGTCGTTCAGGCCG
TCGTTCAAGCCGCCGTTC	AGGCCGTCGTTCGAGCCG
TCGTTCAAGCCGCAGATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_015593810.1|2183343_2183694_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015593809.1|2182846_2183275_+|VOC-family-protein	unknown	unknown	gnl|CDD|319899
NC_021171.1|WP_144061575.1|2184864_2186091_+|deferrochelatase/peroxidase-EfeB	unknown	unknown	gnl|CDD|273606
NC_021171.1|WP_015593823.1|2197129_2198869_-|allophanate-hydrolase	unknown	unknown	gnl|CDD|236177
NC_021171.1|WP_051120144.1|2194037_2195075_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270281
NC_021171.1|WP_015593817.1|2190602_2191361_+|iron-export-ABC-transporter-permease-subunit-FetB	unknown	unknown	gnl|CDD|377092
NC_021171.1|WP_041580453.1|2180428_2180692_-|DUF1292-domain-containing-protein	unknown	unknown	gnl|CDD|377740
NC_021171.1|WP_015593819.1|2192702_2193410_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|200580
NC_021171.1|WP_015593824.1|2198865_2202519_-|urea-carboxylase	unknown	unknown	gnl|CDD|274264
NC_021171.1|WP_015593807.1|2180976_2181408_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015593822.1|2195909_2196704_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213260
NC_021171.1|WP_015593814.1|2187993_2188476_+|GyrI-like-domain-containing-protein	unknown	unknown	gnl|CDD|214874
NC_021171.1|WP_015593813.1|2186122_2187880_+|FTR1-family-iron-permease	unknown	unknown	gnl|CDD|223744
NC_021171.1|WP_041581024.1|2180028_2180382_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015593808.1|2181655_2182321_-|FadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225097
NC_021171.1|WP_015593811.1|2183955_2184804_+|EfeM/EfeO-family-lipoprotein	unknown	unknown	gnl|CDD|271139
NC_021171.1|WP_015593825.1|2202539_2203190_-|DUF1989-domain-containing-protein	unknown	unknown	gnl|CDD|132465
NC_021171.1|WP_015593816.1|2189871_2190606_+|phosphate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213227
NC_021171.1|WP_015593818.1|2191489_2192692_+|MFS-transporter	unknown	unknown	gnl|CDD|340877
NC_021171.1|WP_041581028.1|2195117_2195909_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_015593809.1|2182846_2183275_+|VOC-family-protein	gnl|CDD|319899	cd06588, PhnB_like, Escherichia coli PhnB and similar proteins. The Escherichia coli phnB gene is found next to an operon of fourteen genes (phnC-to-phnP) related to the cleavage of carbon-phosphorus (C-P) bonds in unactivated alkylphosphonates, supporting bacterial growth on alkylphosphonates as the sole phosphorus source. It was originally considered part of that operon. PhnB appears to play no direct catalytic role in the usage of alkylphosphonate. Although many of the proteins in this family have been annotated as 3-demethylubiquinone-9 3-methyltransferase enzymes by automatic annotation programs, the experimental evidence for this assignment is lacking. In Escherichia coli, the gene coding 3-demethylubiquinone-9 3-methyltransferase enzyme is ubiG, which belongs to the AdoMet-MTase protein family. PhnB-like proteins adopt a structural fold similar to bleomycin resistance proteins, glyoxalase I, and type I extradiol dioxygenases.	2.35288e-44
NC_021171.1|WP_144061575.1|2184864_2186091_+|deferrochelatase/peroxidase-EfeB	gnl|CDD|273606	TIGR01412, Probable_deferrochelatase/peroxidase_EfeN, Tat-translocated enzyme. This model represents a small family of proteins with a typical Tat (twin-arginine translocation) signal sequence, suggesting that the family is exported in a folded state, perhaps with a bound redox cofactor. Members of this family show homology to Dyp, a dye-decolorizing peroxidase from Geotrichum candidum that lacks any typical heme-binding site.	1.28548e-171
NC_021171.1|WP_015593823.1|2197129_2198869_-|allophanate-hydrolase	gnl|CDD|236177	PRK08186, PRK08186, allophanate hydrolase; Provisional.	0
NC_021171.1|WP_051120144.1|2194037_2195075_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270281	cd13563, PBP2_SsuA_like_6, Putative substrate binding domain of sulfonate binding protein-like, a member of the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.12322e-88
NC_021171.1|WP_041580453.1|2180428_2180692_-|DUF1292-domain-containing-protein	gnl|CDD|377740	pfam06949, DUF1292, Protein of unknown function (DUF1292). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	0.00205256
NC_021171.1|WP_015593817.1|2190602_2191361_+|iron-export-ABC-transporter-permease-subunit-FetB	gnl|CDD|377092	pfam03649, UPF0014, Uncharacterized protein family (UPF0014).	2.80639e-78
NC_021171.1|WP_015593819.1|2192702_2193410_+|polysaccharide-deacetylase-family-protein	gnl|CDD|200580	cd10956, CE4_BH1302_like, Putative catalytic NodB homology domain of uncharacterized BH1302 protein from Bacillus halodurans and its bacterial homologs. This family is represented by a putative polysaccharide deacetylase BH1302 from Bacillus halodurans. Although its biological function is unknown, BH1302 shows high sequence homology to the catalytic NodB homology domain of Streptococcus pneumoniae polysaccharide deacetylase PgdA (SpPgdA), which is an extracellular metal-dependent polysaccharide deacetylase with de-N-acetylase activity toward a hexamer of chitooligosaccharide N-acetylglucosamine, but not shorter chitooligosaccharides or a synthetic peptidoglycan tetrasaccharide. Both BH1302 and SpPgdA belong to the carbohydrate esterase 4 (CE4) superfamily. This family also includes many uncharacterized bacterial polysaccharide deacetylases.	6.91188e-100
NC_021171.1|WP_015593824.1|2198865_2202519_-|urea-carboxylase	gnl|CDD|274264	TIGR02712, Includes:_Allophanate_hydrolase, urea carboxylase. Members of this family are ATP-dependent urea carboxylase, including characterized members from Oleomonas sagaranensis (alpha class Proteobacterium) and yeasts such as Saccharomyces cerevisiae. The allophanate hydrolase domain of the yeast enzyme is not included in this model and is represented by an adjacent gene in Oleomonas sagaranensis. The fusion of urea carboxylase and allophanate hydrolase is designated urea amidolyase. The enzyme from Oleomonas sagaranensis was shown to be highly active on acetamide and formamide as well as urea. [Central intermediary metabolism, Nitrogen metabolism].	0
NC_021171.1|WP_015593822.1|2195909_2196704_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	3.59563e-127
NC_021171.1|WP_015593814.1|2187993_2188476_+|GyrI-like-domain-containing-protein	gnl|CDD|214874	smart00871, AraC_E_bind, Bacterial transcription activator, effector binding domain. This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.	3.32323e-20
NC_021171.1|WP_015593813.1|2186122_2187880_+|FTR1-family-iron-permease	gnl|CDD|223744	COG0672, FTR1, High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism].	6.37609e-42
NC_021171.1|WP_015593808.1|2181655_2182321_-|FadR-family-transcriptional-regulator	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	8.57324e-47
NC_021171.1|WP_015593811.1|2183955_2184804_+|EfeM/EfeO-family-lipoprotein	gnl|CDD|271139	cd14656, Imelysin-like_EfeO, EfeO is a component of the EfeUOB operon. This family includes the EfeO domain, an essential component of the EfeUOB operon which is highly conserved in bacteria. However, its biochemical function is unknown. EfeO contains an N-terminal cupredoxin (CUP)-like domain and C-terminal imelysin-like domain that may bind iron. Algp7, a member of EfeO family protein from Sphingomonas sp. A1, is found to bind alginate at neutral pH, but does not contain the CUP domain, thus having a role that does not seem to be related to iron uptake. Some members of this family are fused to an N-terminal putative EfeU ion permease domain. The imelysin-like domain of this family also contains the GxHxxE sequence motif and a highly conserved functional site, suggesting a similar role to other imelysin family proteins containing the same motif.	8.22522e-100
NC_021171.1|WP_015593825.1|2202539_2203190_-|DUF1989-domain-containing-protein	gnl|CDD|132465	TIGR03424, urea_degr_1, urea carboxylase-associated protein 1. A number of bacteria degrade urea as a nitrogen source by the urea carboxylase/allophanate hydrolase pathway, which uses biotin and consumes ATP, rather than my means of the nickel-dependent enzyme urease. This model represents one of a pair of homologous, tandem uncharacterized genes found together with the urea carboxylase and allophanate hydrolase genes.	6.13433e-116
NC_021171.1|WP_015593816.1|2189871_2190606_+|phosphate-ABC-transporter-ATP-binding-protein	gnl|CDD|213227	cd03260, ABC_PstB_phosphate_transporter, ATP-binding cassette domain of the phosphate transport system. Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).	1.91121e-75
NC_021171.1|WP_015593818.1|2191489_2192692_+|MFS-transporter	gnl|CDD|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.17322e-21
NC_021171.1|WP_041581028.1|2195117_2195909_+|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	7.16504e-61

Protein sequences

>NC_021171.1|WP_015593814.1|2187993_2188476_+|GyrI-like-domain-containing-protein
MDFNIIERESFQVVGIKREFLCGAGDAGIPGVPEYWLESSKNGTFDQLFPLHNGEIPGLLGVTDNFNPVKNVVDYWIAVEHNGDVPSGLASIVFPASKWVVFEVRGPIPSAMINAWQQIYSGWFKVNGFEPAAKIAPIEAYFDPDLDSPNSLNQIWVAIK
>NC_021171.1|WP_015593813.1|2186122_2187880_+|FTR1-family-iron-permease
MLYFTNKWKLLMVFTGFIIFFVSANPVVGEENHDELFVLIGDSLMKAKDGDSVHVSKNIDLFTKEWQSIKNRDSKLAKKVDQKLKAVQDLLTEQKVDNQALSEALSSLSSAVVQYEKEQNPSDKGKGKEKVTQLVPLIYHMKEAINEKDQTVVMAQYQDILTQWNMSEKAVHDESIVTYGNIEKDMALIRIAITQDPPNPQKALSSLDDLSRELENFMSGKVSKEVVGDYSLADMATILSKAEKAISKDQYKKASTHLELALTIWPTVEGDVKTRDSKLYSDFETEIPTAISILNSKVVNAEKAQGIVQKMNFRFAPLMSKTDYTLWDASLILLREGLEGLLVVATLIAFLKKMGQSNKQKWIWIGVVAGILASGLLAIVINFLFSQITAASSREYIEGFTGVIAVMMMLTVGAWLHNKSNIGNWNKYIDKQMKMALAKGSLFSFSMVSFLSVFREGAETIIFYTGITPYISLQDLVLGVVLAIFILILVGFAIIYFSAKIPIGLFFKVATILVYCLAFKILGISIHALQISKVLPTTTMDVFPFLDFLGIYPTWETSIVQLILVGIIIAMTYLIRKKDRKMMAT
>NC_021171.1|WP_144061575.1|2184864_2186091_+|deferrochelatase/peroxidase-EfeB
MLKTAGVGGVGALLGASGLEGLLAISENNTKNHEIQQIVTFYGKNQSGITTKTQNHVYFIALDVTTSKKEDLVNLFKDWTTAAKRMSNGKAVDPLSSNEFLPPKDTGEAAGLSPSNLTITFGVGPNLFSNGNQDRFGLKHKQPKELVDLPKFPLDALEDEWSGGDLCIQACADDLQVVFHAVRNLLRIARGTAKLRWAQTGFQRSKQADFKNTTPRNLFGFKDGTVNPVVTNKKEMNQHVWVQPGDGPDWLVNGTYLVVRRIQMFIEVWDRSTLKEQENTFGRYRSNGAPLGQKNEFEQLDLDKKNELGQYHIPENSHTRLSHGDGSQKILRRAYSYSDGMDKKTGSFDAGLLFLSFQRSPSKQFIPIQHRLAKMDKLNEYTTHRGSAIFACLPGTEQGGYIGETLFK
>NC_021171.1|WP_015593811.1|2183955_2184804_+|EfeM/EfeO-family-lipoprotein
MEWYKVSGIILLSSSLLLGCANTDKSSSNEKVKVVKSHSTESFKGVTDEYKVYAIGEIEEFVKATDEFTTAVINGENEKAKSLYALARMHYERAEPIAEVFGDLDPKIDAREGDVPEQEWGGYHRIEKGLWIDNTTIGYEQYATQLMKDVNLLRAKVDTVEVTPELLISGAVDLLNEVSTSKVTGEEDRYSHTDLYDFVANVQGAEKIYQLLKPALTKKDAELSKEIQTRFDNVYLLLNLHKNGDGYKLYTELTGSQVKELSQAIDALAEPLSQIGILTEEL
>NC_021171.1|WP_015593810.1|2183343_2183694_-|hypothetical-protein
MKSKIHRCNCRETWAVQNRKTYITAKTVLLNGKWDTELKPERKGNPKGFVISNNSEEIMINPSLELLEKFSKVTKLIYDKKHVYFNVSHGEFLYFAEDGTCYILKQREPCLDNNLF
>NC_021171.1|WP_015593809.1|2182846_2183275_+|VOC-family-protein
MSVDVYLNFNGNCREAAEYYAEVFGTEKPQIMTFGEAPPNPEYPLPEEAKNLVMHTRLTISGSNVMFSDVFPGMPFVAGNNISLTVVSKNMDEIKSSFNKMKVDSNVGMELQETFWSKCYGQLTDKFGINWQFSYDNGEVAM
>NC_021171.1|WP_015593808.1|2181655_2182321_-|FadR-family-transcriptional-regulator
MEIKIKKASDTVSDYIESLINQNEYLPGDRLPTIKEWAERLNVSVGTIREATHILKTKGLIEVRQGEGIFVRKVDLKEIAPMMNIALVQMDDLKELMDFRNIIEIGAVQLAAQNRTLEDLQEMKQVLEEMNTEDKEKREETDFLFHCAIAKASHNSLLLFLFQSYSPAIKSLMHRYSIDLLDHNWNDHYLIYQGIEQQDTLLAIHNMEKHLTEAKQRAFPS
>NC_021171.1|WP_015593807.1|2180976_2181408_-|hypothetical-protein
MTNGDLRVKLYSFFSNHEEQISLFLAVEKMINSIGPASIEIRKSQISFGTKTKFAWVWLPQPSSKKRPENSIVLTFGVGRFIENKRIVDSVEPYPGRWTHHVIIQNEADLNKEVFTWLCEAYTFSLIRGRNRKSAFQIPFRAS
>NC_021171.1|WP_041580453.1|2180428_2180692_-|DUF1292-domain-containing-protein
MNSFDQRDYITVEDEDGIEKQFAVEALFNMENKNYAFLRSVNNKNDLFVMAVEDDEDGQVLTKIKDQQKREMVLDAYQIAVQCNPAE
>NC_021171.1|WP_041581024.1|2180028_2180382_-|hypothetical-protein
MSEGLKKQIEHEINGIKFTKNFRSPTAEEWYVFLPSFKDPVTGGAAGKTIVHYNLYDTKNFFINTTIIFDDPALHEGKLYRLVYAVSDEIVNRLVGYADTLLSVHSGQNSYNAEYKQ
>NC_021171.1|WP_015593816.1|2189871_2190606_+|phosphate-ABC-transporter-ATP-binding-protein
MYLEIELKNVSKTFINDNETFSVLKGISADVKKGEIVTIVGPSGSGKSTILSLCNLLQTADEGDICIQGKEVRRWNIQDLRCQVGIAFQDAPMLKGTALDNLSLPAQLQGRVLENPNQYMEYVGLSVDLLTREAKDLSGGQRQRLSLARTLVNEPSILLLDEITSSLDSSASYEVEELIMRINRERHTTILWVTHDLLQAERVGDQTWLVVDGKIIEAAATKQFFTNPKNEQTKQFLEMKREYK
>NC_021171.1|WP_015593817.1|2190602_2191361_+|iron-export-ABC-transporter-permease-subunit-FetB
MSLFAILLSFGFVVISLFLTLSFKLGLGRDLIITSIRATLQLFIVGYILKMVFGFDHPLVVILMLLVMIVVAAKSAAKRGKGLPHIFWIIFFTISIVEIITQGFLLGLRIVPATPPYIISISGMIIGNSMVIANLFLNRIKGELEMRKEEVLLVLSLGGSIKQSIYPILKQSIRSSLIPTIEGQKTIGLVQLPGMMTGQIIAGADPVQAVRFQLLIVFMILSAASLTAIILGFLIYPGLFNKHHQLDIQSWK
>NC_021171.1|WP_015593818.1|2191489_2192692_+|MFS-transporter
MKTGKWTALFWIAVSELFALSLWFSASVILPELKGIWSLTAFTEAWVSAAVPIGFVVGALVSSYFGIADQHNPRKIFAISATIGAVVNGVLIMADNAILGIFLRILTGITLAGVYPTAVKILTQWFPQKRGLPVGILIAALTLGSSLPHFVILFFSAVNWKMVILITSILALISAWIVDRILEDAPDVSVSSFSFKLLKKVMVNKPVMLANYGYFGHMWELYAMWTWLPAFLTASLKISLPDAEQSLIALISFISIGIAGGIGCVLGGLVADKLGRSNLTLISMFISGLCAVLIGFTYGHSFWLTLVFAVFWGMSVISDSAQFSVAVSEFSEKEYLGTALTFQMCVGFLITIISINIIPIVQKSIGWEWVFTLLSIGPILGIIAMFKYKHFETRREITKK
>NC_021171.1|WP_015593819.1|2192702_2193410_+|polysaccharide-deacetylase-family-protein
MKKRIHILLLILALFLLLLFGIYKLMNSRTHQIFGGITNHVNTNEKVVALTFDDGPTKNVDKILPVLDKYNAKATFFLIGNELKQNPKLGRKIVESGHQIGNHTYNHERMIFKSPIYIKREIEKTNKEILKTGYQGEIDFRPPNGKKLVALPLYLKSHHLDTITWNLEPDTFYSSVSKKVNYVRKNVKPGSIILLHPMYDQTGDELKAIEGILKSLTEDGYTFVTVNELQKYSED
>NC_021171.1|WP_051120144.1|2194037_2195075_+|ABC-transporter-substrate-binding-protein
MIEVDLMKKKHTLLAILLVGVLLLTACGKSTDKVSNSEDKKTETIKIGFSALPSWYLWHLVEEKGFFKKHDVDVELVWFPVYADSLSALNAGQIDGNSQALLDTISPLDKGINLKTVFITDNSEGGDGLVAEDQIKSIKDLKGKRIGTEIGTIEHFFMLTALEDAGLQESDVEFTNMAVPDAGNALIAGKLDAAGLWEPFLSKSVQKGNTHKLVTSAEYPGLISDVFAVSEGASKEKKDELQKVVAAWFDAVDYLANNHDEAVKIIAKKAGISEEELEVGLQGFRVFTPDENLAAFKTGNSYDSFYYTAEKNAEFLKRLEYIKDVPDFKDFVDTSYIENEIKQNK
>NC_021171.1|WP_041581028.1|2195117_2195909_+|ABC-transporter-permease
MRVLISIREEIPKKWYFIGVTIAFLLLLITWNVLSFLKLVDEVFLPTPIDVLFSLFQSLASLDFWNQIGISVYRVFMGFLLACAIGIPLGILAGTFKFAESFILPISEFIRYMPAAAFIPLIMVWAGIGETAKILVIFIGCFFQLVLMVTDDTYRISKDLLSASYTLGANRRQVINRVIIPAMLPKLMTTMRMIMGWAWTYLVVSELVAANSGLGYTIMKAQRFLDTESIFVGIIVIGLLGLIIDRGFAVANKKIFPWVEGGN
>NC_021171.1|WP_015593822.1|2195909_2196704_+|ABC-transporter-ATP-binding-protein
MLNVLKSQFEIEQSQIEIEINGLSKVYKSKNGIFQALDDVSLYVKNEEFVSILGPSGCGKSTILRILAGLEDATSGSVKVAGEAVLGPSVKRGMVFQSYTLFPWLTVRENIEFGLKLKKLKAKECKEISDKYLVLVGLERFANSYGKELSGGMKQRVAIARSLANSPEVLLMDEPFGALDAQTKQSMQQLLLDIWKKEKTTIVFITHDIDESIFLSQRIYVMEARPGKIKEEINADLHLFKNGELVDVNQFMKVKKHIISLLKH
>NC_021171.1|WP_015593823.1|2197129_2198869_-|allophanate-hydrolase
MKTTNLPLKLSINEIQVKYKEKVLTPEALIQEIVARAEEDKDFNIWITPPSIEHIQPYLNQLKKMDPEEKPLWGIPFAIKDNIDLAGVPTTAGCAEFAYNPDEHATVVHRLIEAGAIPVGKTNLDQFATGLVGMRSPYGETKNALNPDLISGGSSSGSAVSVARGLTAFALGTDTAGSGRVPAALNRLVGYKPSLGAWPVKGVVPACASLDCVTVFANELTDALLVDQVARGFEETDPWSRSIPRRTNTLPEKICLLQDPPEFFGPFSSQYKLAWEAAVERIKELNIPIEYIDGRYLSEAAAVLYDGPWVAERWADLGSFIEANEQTAFPVTEAVLRSGAKPEYDAVSIFKAMHTLQAFKQKAHQQLKNAVLVMPTSGGTWTRTKVRENPIQTNSDMGLYTNHCNLLDLSAVAIPAEDAAENLPFGISLFSGNENEHLISGLAESFLHGCPPPVNMATTLVAVCGLHMRGYPLEKQMIEYGAVFIREAKTAPIYNLVKLPSQPAKPGLIRTNATGSSIELELWEMPLSEFGPFATLIPSPLGIGKIELEDGTKVPGFVCEAAAAESAEDISSLGGWRYL
>NC_021171.1|WP_015593824.1|2198865_2202519_-|urea-carboxylase
MFRKILIANRGAIAVRIERTLQRIGIKSVAVYTKADQDSLHVDLADEAILIGEGAAKDSYLNADLILRTALDTGADAIHPGYGFLSENAAFARACSDHGITFIGPTPEQMELFGLKHSAREIAVKAGVPLLPGSPLITDLSIALSEAERIGYPVMLKSTAGGGGIGMRVCADELSLREAFDSVCRLAETNFNNGGVFLEKYIKKARHVEVQIFGNEYGEVAALGERDCSIQRRNQKVVEESPAPCLSPSVREEMQTAAKRLALEVGYRSAGTVEFLYDPVAERFYFLEVNTRLQVEHGVTEEVLNIDLVEWMVREAAGKLRSLDSLFSTPKGHSIQARIYAEDCLNDFRPSGGQLDQVYFSEKARIETWVRDGLTVTSHYDPMLAKIIVHADSREAALDQLTAALENTRLYGITTNLQYLQALLHEDDCRSGNVHTQMLKGFSPNERAIEVLDGGIQTTVQDYPGRVGHWDVGVPPCGPMDPFSFRIGNKLLGNKTSAAGLELTLRGGSYLFRGDTVFCLTGADMNAQLDKTDVPLYKVITAKRGQMLTFGEAAQGMRTYFLVAGGLDMPLHLGSASTFTLGGFGGHGGRALRTGDVLQVNPSNSTTLTKRDAKKLSSLVLPVNKRPILMKEWTIGVILGPHCTAEFLLPDYLMQLVETSWEVHFNSSRTGVRLIGPAPLWTREDGGEAGLHPSNIHDNAYAIGTLDLTGDMPILLGPDGPSLGGFVCPVTTASAEFWKIGQLHAGDRIRFQLLTLEEANKMRQVQEQFLEAIGTNGQEIPALPSLPAESVQLAPNYPILVQRSDSRFPITIRAAGDEHVLIEYGEMELDLLLRFQVHALMEAIKDHSDIPILDLTPGIRSLQVHIDSAKMSISSLCTIIEAIDRSLPALEEIEVPSRIVRLPLSWDDPATQLAIDRYQQNVRPDAPWCPSNLEFIRRVNGLKDLDDVKRIVFDANYLVLGLGDVYLGAPVATPIDPRHRLVTTKYNPARTWTPENAVGIGGAYMCVYGMEGPGGYQFVGRTVQVWNRLRETESFQDGKPWLLRFFDQIQFYPVSADELLKMREDFLRGRFEIDITETTFKLGDYLAFLDSIKDSADDFRKTQQAAFHAERESWRELGLAEYVSEHEVTETIEEVLPEGVEAVRCTMPGSVWKVLVSAGDEVKKGETLIIEESMKMEFPQAAPCDGFIEMVYVSPGDEVHAGQLIVSIKKEKARCIA
>NC_021171.1|WP_015593825.1|2202539_2203190_-|DUF1989-domain-containing-protein
MAVLNHVVSERKIENAIYNQTVLAGDGWTYTLEPGQVLRIVDLGGNQAADTLFYDANQPSNHYSAVNTIQRQGNVYLSTGSVLVSESGKELVKIVADTCGRHDTIGGACSAQSNTVRYSHDTLPMHNCRDTFMLQLSKYDSRFTKRDLAPNVNFFMNVPVTPDGGLTFEDGVSAPGYYVEMQAVNWTIVLISNCPQLNNPCNAYNPTPIQLLIWNN

Crispr_ID: NC_021171_5

• CRISPR_ID: NC_021171_5
• CRISPR_location: 2701110-2701220
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021171_5

Consensus_repeat	Method
CTCTGTGGACGGGAATCAGCAGACTTG	CRISPRCasFinder

spacers of NC_021171_5

>5.1|2701137|57|NC_021171|CRISPRCasFinder
ACCTCGTTCCGACTCCTCTGTGGACGGGAATCAGCAGACTTGACCTCGTTCCGGCTC

CRISPR arrays and Neighbor proteins around NC_021171_5

CRISPR arrays

The CRISPR arrays of NC_021171_5

>merge|NC_021171|5|2701110-2701220|CRISPRCasFinder
CTTGATGGACTGGAACCAGCAGACTTGACCTCGTTCCGACTCCTCTGTGGACGGGAATCAGCAGACTTGACCTCGTTCCGGCTCCTCTGTGGACGGGAATCAGCAGACTTG

>NC_021171|5|4|2701110-2701220|CRISPRCasFinder
CTTGATGGACTGGAACCAGCAGACTTG	ACCTCGTTCCGACTCCTCTGTGGACGGGAATCAGCAGACTTGACCTCGTTCCGGCTC
CTCTGTGGACGGGAATCAGCAGACTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_015594248.1|2694135_2695299_-|MFS-transporter	unknown	unknown	gnl|CDD|340928
NC_021171.1|WP_041580508.1|2705803_2707951_-|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl|CDD|223223
NC_021171.1|WP_015594256.1|2700269_2700545_-|ACT-domain-containing-protein	unknown	unknown	gnl|CDD|178923
NC_021171.1|WP_015594258.1|2702984_2703485_-|acetone-carboxylase-subunit-gamma	unknown	unknown	gnl|CDD|226994
NC_021171.1|WP_015594265.1|2713027_2713834_-|adenosylmethionine-decarboxylase	unknown	unknown	gnl|CDD|235480
NC_021171.1|WP_015594255.1|2698893_2700255_-|PFL-family-protein	unknown	unknown	gnl|CDD|180009
NC_021171.1|WP_144061473.1|2710512_2711433_-|DUF1002-domain-containing-protein	unknown	unknown	gnl|CDD|377628
NC_021171.1|WP_051120154.1|2712543_2712921_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_041580509.1|2712214_2712400_+|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_041580510.1|2713962_2715651_-|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|223733
NC_021171.1|WP_015594251.1|2696718_2697249_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|182012
NC_021171.1|WP_015594252.1|2697397_2698003_-|DedA-family-protein	unknown	unknown	gnl|CDD|223659
NC_021171.1|WP_015594259.1|2703512_2705783_-|hydantoinase-B/oxoprolinase-family-protein	unknown	unknown	gnl|CDD|223224
NC_021171.1|WP_015594263.1|2711734_2711935_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_021171.1|WP_015594253.1|2698233_2698437_+|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015594261.1|2708226_2710245_+|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225822
NC_021171.1|WP_015594247.1|2693667_2694066_+|GtrA-family-protein	unknown	unknown	gnl|CDD|377229
NC_021171.1|WP_051120153.1|2695342_2696197_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015594250.1|2696210_2696717_-|zf-HC2-domain-containing-protein	unknown	unknown	gnl|CDD|227949
NC_021171.1|WP_015594254.1|2698436_2698634_+|YwbE-family-protein	unknown	unknown	gnl|CDD|274807

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_015594248.1|2694135_2695299_-|MFS-transporter	gnl|CDD|340928	cd17370, MFS_MJ1317_like, MJ1317 and similar transporters of the Major Facilitator Superfamily. This family is composed of Methanocaldococcus jannaschii MFS-type transporter MJ1317, Mycobacterium bovis protein Mb2288, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.95295e-111
NC_021171.1|WP_041580508.1|2705803_2707951_-|hydantoinase/oxoprolinase-family-protein	gnl|CDD|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	7.5161e-170
NC_021171.1|WP_015594256.1|2700269_2700545_-|ACT-domain-containing-protein	gnl|CDD|178923	PRK00194, PRK00194, ACT domain-containing protein.	6.50197e-38
NC_021171.1|WP_015594258.1|2702984_2703485_-|acetone-carboxylase-subunit-gamma	gnl|CDD|226994	COG4647, AcxC, Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism].	8.45702e-74
NC_021171.1|WP_015594265.1|2713027_2713834_-|adenosylmethionine-decarboxylase	gnl|CDD|235480	PRK05462, PRK05462, adenosylmethionine decarboxylase.	0
NC_021171.1|WP_015594255.1|2698893_2700255_-|PFL-family-protein	gnl|CDD|180009	PRK05313, PRK05313, hypothetical protein; Provisional.	0
NC_021171.1|WP_144061473.1|2710512_2711433_-|DUF1002-domain-containing-protein	gnl|CDD|377628	pfam06207, DUF1002, Protein of unknown function (DUF1002). This protein family has no known function. Its members are about 300 amino acids in length. It has so far been detected in Firmicute bacteria and some archaebacteria.	4.97805e-84
NC_021171.1|WP_015594251.1|2696718_2697249_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|182012	PRK09641, PRK09641, RNA polymerase sigma factor SigW; Provisional.	6.89505e-45
NC_021171.1|WP_015594252.1|2697397_2698003_-|DedA-family-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	9.13494e-45
NC_021171.1|WP_015594259.1|2703512_2705783_-|hydantoinase-B/oxoprolinase-family-protein	gnl|CDD|223224	COG0146, HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	5.85745e-160
NC_021171.1|WP_015594263.1|2711734_2711935_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.03743e-32
NC_021171.1|WP_041580510.1|2713962_2715651_-|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	7.2812e-160
NC_021171.1|WP_015594261.1|2708226_2710245_+|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	1.08296e-152
NC_021171.1|WP_015594247.1|2693667_2694066_+|GtrA-family-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	1.74546e-14
NC_021171.1|WP_015594250.1|2696210_2696717_-|zf-HC2-domain-containing-protein	gnl|CDD|227949	COG5662, COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription].	6.9055e-08
NC_021171.1|WP_015594254.1|2698436_2698634_+|YwbE-family-protein	gnl|CDD|274807	TIGR03833, TIGR03833, conserved hypothetical protein. A pair of adjacent genes, ablAB (acetyl-beta-lysine biosynthesis) encodes lysine 2,3-aminomutase and beta-lysine acetyltransferase in methanogenic archaea. Homologous pairs, possibly with identical function, occur in a wide range of species, including Bacillus subtilis. This model describes a conserved hypothetical protein, small in size, with a phylogenetic distribution moderately well correlated to that of the acetyltransferase family. This protein family is also described as DUF2196 and COG4895. The function is unknown. [Hypothetical proteins, Conserved].	6.66972e-31

Protein sequences

>NC_021171.1|WP_015594256.1|2700269_2700545_-|ACT-domain-containing-protein
MNKRRAVVSVVGKDQVGIIAKVTNILSENSINILDISQTILQDFFTMMMIVDVSGTENLDVLQKHFDEVSEELSLKINIQLEEIFQAMHRI
>NC_021171.1|WP_015594255.1|2698893_2700255_-|PFL-family-protein
MNIAIQEMMETIRMVQMENLDIRTVTMGINLHDCADSDFEKMNDRVYDKIVNYASRLKEVAEEVEKEFGIPIINKRISITPIAEILGNATKDQAIILAKTLDRAAVILGIDFIGGYSALVHKGIAKGDQTLLDALPEALSVTERVCASVSVATTRTGINMDAVSKLGVIIKEAAERTKDQNGLACAKLVVFCNPVEDNPFMAGAFHGSGEGEVVLNVGVSGPGVVLNALKRHPEADLGEVSEVIKKTAFKITRAGELIGRVVAERLGVPFGIMDLSLAPTNAINDSVAEILEEIGLERVGTHGTIAALALMNDAVKKGGAMASSYVGGLSGAFIPVSEDNGMIRGILDKSLTLSKLEAMTCVCSVGLDMIAITGDVTPSTLSAIIADEAAIGMINKKTTAVRVIPVPGKIEGDLVEFGGLLGRAPVMGVNPFSSEKFIRRGGRIPAPLQALIN
>NC_021171.1|WP_015594254.1|2698436_2698634_+|YwbE-family-protein
MNGQNRKDITPGTAVEIVLKSDQKTGKLTSGVVKDILTNSSTHPHGIKVRLTDGQVGRVQIIRGK
>NC_021171.1|WP_015594253.1|2698233_2698437_+|hypothetical-protein
MTDSNQQDQTETPKKKMSLQEAIKQQLENKKNQTSNNKSFSNGSTATKKLKSQQTKKANNQARRTGV
>NC_021171.1|WP_015594252.1|2697397_2698003_-|DedA-family-protein
MESWITHFMEQFGYLGIFLLMFLENVFPPIPSELILTFGGFMTTYSDMNILGVIFAATGGSVLGAVILYGVGLLIDVERLLKIIDKWGKYLRIKQKDILKADDWFDRRGYWTVLFCRMIPLVRSIISIPAGMSNMKFLLFLFFTTVGTLIWNLILVTAGALLGKSWDKVLYYMGIYSNIIYCILGVLVFVYLIITFKKKRK
>NC_021171.1|WP_015594251.1|2696718_2697249_-|sigma-70-family-RNA-polymerase-sigma-factor
MDELLYQLIIEAKRGNEEAFSSLVTRYKRQVFRHAFAMVNDRMEAEDISQEAFVKAYFSISKLNNEYGFVSWLTRIVSNLCYDRIKKKEKTVPFGNGEKDLLLSTYSSHNQSQMRMTLQEAMQELSVEYRTVLVLREVEGYSYNEMAEILHIPLGTVKSRLSAARELLKKELVRGD
>NC_021171.1|WP_015594250.1|2696210_2696717_-|zf-HC2-domain-containing-protein
MHDHVKSLLSAYVDDELDSEETSIIDHHVALCEECKHELDHLMFMKKEIMALFHFVEAPDEQFEQSVMKEIADLSWKKRNVFRPLLLGSTFAIAFIFGVVFLKMGHFLFIGMKLATAFVKMALSVVHALVAISSSIPSIFGVFIITSLIIIAISGWSIRYLLETNTTG
>NC_021171.1|WP_051120153.1|2695342_2696197_-|hypothetical-protein
MKVARLYCVFTIILIFFIVAPPAMAKENHILAKKQTTIPEQQSVESVIVVGNDVVIKGSVTIAVIVVNGNLKINNKAHIKGPVVVIGGDVEQQKGARVTEQVLSLNLNNETKNSLFLGWSLFLGSWLLKVAGSILLITITVLSGVIFKKRIKSATGYLKVQPGKLVLTGAVAFLGICAFITLLSITIIGIPIVVILLLGVLISFFMGMATISKFLVDRMASMSEKPEWLLLLTAAFVLVSFMNFPLLGGLVSLMIIWLSLGFSVKRTYDFISNLKNRKQLNNNK
>NC_021171.1|WP_015594248.1|2694135_2695299_-|MFS-transporter
MRNLKIVAMVSFFTDLGTYMVYPLVPLFLVSVGTTPLIIGVIEGVAESITSILKFVTGYFSDRMKNRKRLAIYGYGFSAVGRLLLIFSQSWVGVSLWRIADRVGKGIRTAPRDALIIEAGGKENHGRSFGIQQTMDMLGSAIGVAVAFGLIFIGGKQYSTVFLYSIIPVLIGFLLLFFIKDPKGITLSHTKSFRLNLRGLDKQLKQLLLVILLFTIANSSNQFLILRASDIGITTDKILLLYLVYHLSTSILSYPIGFLSDKIGRKNLLVGGYILYGFIYLAFAMIHSARWIWLLFALYGIYTGMTKGVEKALVADCAPSHLKGTLMGLYAMITGIGLLPASVLTGFIWDHFGAASSFYFNGALALVSAGFIYLVLSRKTERTAPVN
>NC_021171.1|WP_015594247.1|2693667_2694066_+|GtrA-family-protein
MLHPFFRFLIVGLVNTMVGLSSMYILLHAAGLSYWLSTFIGNSIGAVVSYFLNKTFTFKSNAPVGKSALRFMIVILVCYFISYYLGKQFTNWALDQVSFISSSFKTDIAVLFGTGLYTISNYFGQKVFVFSK
>NC_021171.1|WP_015594258.1|2702984_2703485_-|acetone-carboxylase-subunit-gamma
MTQYDRKTIEELIDGTIDFYKLKEMLSSFKDADRFEKYVSILQERVAWKDPILLPAGLHLYIVQKANGDRIVKCDCGHEFCQASDNWKLHSLINVRDTQEKLSDLYPKMLAPDPEWQVIREYYCPECAAQLEVEAVTPWYPILKDFEPDIDTFYTEWLKKPLPVAK
>NC_021171.1|WP_015594259.1|2703512_2705783_-|hydantoinase-B/oxoprolinase-family-protein
MNRTEKGLQSQKNIGWDGKTLQQMRTEVDEVSRETGHYAGLRTLPLKETDPIRYEKIFSKLRGGVVHARETAKKVAASPIVEQEGELCFTLYTPEADSVVTSTGIIIHVGTMGSAIKYMIKNDYESNPGIEDGDIFCNNDCQIGNVHPCDVHTIVPIFHNEEVIGWVGGVTHVIDVGATAPGSMTVGPVSRYDDGYQVACRKIGKSDTLLKDWVIESQRSVRTTKYWLLDERTRIAGCHMIRDLVLNIVKEEGIDTYKHFIREVIEDGRRGFVNQVKSMLIPGKYRQVSFVDVPYKDLDVPPYARVNTIMHAPTEMTVHKDGKFQINFEGVNRWGWHSYNATPVAITSGIWVMMSQTLIPNDRVNDGALYASHFDLPYGSWLNPDDIRTAHSYAWHFLVSAWSPLWRALSRNYFARGYLEEVNAGNANTSNWLQGGGVNQFGENHAVNSFESAAEGIGASAVRDGISHAAAIWNPEGDMGDMEIWELAEPLLYLGRSIKPNTAGYGKYRGGSGYETLRMVYGAKDWTMFFMGNGYMSSDCGLMGGYPAASGYRFEAHGTNLKDRIDKKLPIPTGGDTDPDNPEYEQLVDATEIIRDKQSITTETIFENYDLYLNYLRGGPGFGDPLERSPKSIEEDLNDGHLLPRFAEKVYGAVINESQKGNFIVDEKATEERRNQIKRARLKRGVPVSEWMKQERQTIINKEAAVQVRHMYASSFALSETFAAEFKEFWDLPKEWKMTEAELGVPIFGAKINHNQ
>NC_021171.1|WP_041580508.1|2705803_2707951_-|hydantoinase/oxoprolinase-family-protein
MDTMTTRKAQILAIDAGGTMTDTFIIDDNGDFVVGKAQSTPEDESIGLLNSARDALTYWETTVEAEFPKLLAGVYSGTAMLNRLVSRKGRKVGLIVNKGMEDFHRMGRAIQAYLGYSYSDRLHLNTHRYDPPLVPRELTKGITERVDIFGNVVIPLYEHEVEGAVQELLEQNVEAIVISLLHSYKYPAHERKIRDIAIATLKKAGKDIPTFASVDYYPVRKETHRTNTTIIEAYAADPSRETLNKIDDMLREHGTTFDLRVMASHGGTISTQANELARTLVSGPIGGVVGAKYLGEALGIPNIACSDIGGTSFDMALITQGDLSINTSPDMARLVLSLPLVAMDTVGAGAGSYVRIDPNFKSLTLGPDSAGSKVGVCYPEGGVETVTVSDCHVVLGLINPDNFLGGEVKLDPVRAYEAVKKQIADPLGLSIEDAAYGVIDLLESQLRNYLESMILGKGYSPSQYVCFSYGGGGPLHTAGYTKGLGFEEVLVPAWAAGFSAFGCGAADFEYRYDKTLDINVDQIAGDDIKLMAGKELQGAWDELMEKVAAEFEKNKFDRKDVDFRLYFRMQYQGQLNDLEIEAPIKSFKSVLDWENLVEAFEDTYTRIYAKAAKSPELGYSITGAIIRGIVDVAKPRIPEEPLLGEKPAGDAFLGKRNVYWKGEWIKANIWEMEKLNPGNKIGAFSILESPATTFVIPPGFEAYLDEHRIFHLKEF
>NC_021171.1|WP_015594261.1|2708226_2710245_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MGNNFISIFSTRNLPDRTRELATLWENFVSKAWGEVSPNKIRKNVLESWKRCQEINVNPSQLQTNTFLTDMGLKQVLEKSELYKISKPIIDDFYQKMFGTGYLITLTNRNGYIIYLKGEKQEWREAEKMNFIPGMDWSEKSAGTNAIGTSLATRTPIQIFSAEHFCLGCHPWTCSSAPITHPFTKEMIGAVDFTGFWGNAQPHTLGLAVSLAQIIEKQFAEIYMKVNYYLTESFFQSVNKWKKDHVLVLNHTFFTVKSSELLARYFKLTPGTDLRLNLSFHSLINELNQALPGKDEVYPAIEINIGDFQVHSIEKLHYMENLVGYRVIFIDKNKKALRSTSRLRLKDGSWEDVIGVSEGFLDTLYKCQKAAMSNVPILLLGESGTGKEKIAQSIHKSSHRCDQPFLAINCGAIQKELIGSELFGYDRGAFTGASKEGKKGKFEEAHGGTLFLDEIGEMPLELQVHLLRVLQEKEITRIGSSKPISVNVRIIAATNKNLYDLCNKGLFRQDLFFRLNVVSVNIPPLRERKDDLTLIVEYFLKQLTNKYEKEQLSLSEDIFKYFLEYPWPGNIRELQNVLEHAVIFSDSSLITFEDLPAYLIEYGISNSSTNQKPKLSLIHDEEQKVLIRLLEETNWNLSAVAKRLNIARSTLYRRLKKYQLVQNRSLEKGSVY
>NC_021171.1|WP_144061473.1|2710512_2711433_-|DUF1002-domain-containing-protein
MIMKKIIKWVALAAVLTLTLSIGSKALASDNSSSEESINEKYGLPIVVYGAALSPSQKDEVRSLLGVTDPSKVKEITVTGEDIYTYIKGDRNSNMYSSAKITRKDSGEGLVIKQVTPENITEVTDEMYANALLTAGINDAVVEVASPIKVSGHSALVGIYKAYDAGEGAGLNKDRTEVANQELNLATDLAKKEGLDKDKVSELLTEIKKEIADQNPASKEDIAKIIDDKLKELGIQLSDQDRQLLIDLFEKMRGLNINFDNVQSQLDNLSKDITNRIEQAIGDKGFLQKVATFFKELITSIKNIFS
>NC_021171.1|WP_015594263.1|2711734_2711935_-|cold-shock-protein
MENGKVKWFNAEKGFGFIERDGGEDVFVHFSAIQGEGFKTLEEGQAVTFDVEKGARGPQAANVRKA
>NC_021171.1|WP_041580509.1|2712214_2712400_+|hypothetical-protein
MKHLNNLYNAGETVNVKATGETVTILKWKYVKNMKRFSYILTEYPGTFYFEEELTRNQLSE
>NC_021171.1|WP_051120154.1|2712543_2712921_-|hypothetical-protein
MEDNRQMFGGYAGMGGYPGHGGYGGMGGYPGHGGYGGMGGYPGHGGFGSPMGYPGHGGYPGGYGHHYGHYGHHHHHHPHHFPGIYGGMGGYPGHGYPGHGGYPGYGGYPGMGITIGVPRDYDYLE
>NC_021171.1|WP_015594265.1|2713027_2713834_-|adenosylmethionine-decarboxylase
MTLSPEQRVELYGFNNLTKTLSFNMYDICYTTTKSEREAYFHYIDDQYNADRLTNILSNVSDIIGAHVLNIAKQDYVPQGSSVTFLVSEGPVIEVPNGSFAESPGPLPDAVVLALDKSHITVHTYPESHPDEGISTFRADIDVSTCGEISPLKALNYLIHSFDTDIMTIDYRVRGFTRDISGHKLFIDHEISSIQNYIPDEIKNIYHMIDVNVYQENIFHTKCKLREFDLNNYLFGYTKEKLSSKEVEEITEKLNLEMDEIFYGKNIQ
>NC_021171.1|WP_041580510.1|2713962_2715651_-|AarF/ABC1/UbiB-kinase-family-protein
MIRKRFRHIQRYREIVNAFIRYGFGFVIKEMGLIELLSMPKRLFVEVNPETETQNTSTGERIKMFLEELGPTFVKMGQVASTRYDLIPSEIVKELENLQDNAQQFPFEVVQETIEKELGQPIGQVFNEFCEIPIAAASIGQVHYAILKTGEKVAVKVQRPNMRSIIDTDLEILQDLAILAEQRLAWAARYQIRDIVDEFSKSLREEVDYSIEGRNSERIAKQFIDDPKVVIPKVFWEYSTKKILTMEFVEGTKLYETEMLHQMGNDNKILAKRIVDSILHQVLIEGYFHGDPHPGNILALPNDVIIFLDFGMVGRLTPDMKHHIASLVIALMRQNTDDVIKAITRMGIVPSDINISMLRGDVEKLNETYYDVPLSKVSLGQVVNDLFLVAYRHNIRIPPDLTLLGKTLLTMEGIVVKLDPEISILKVAEPFGRRLLMERYDPKKVVGNLWHQIVDLGEFVKDLPKGLKELTLLFKNGKVRQEISFPEIDLILAKLNQISNRISFSIGLLSFSIIICGLIIGSSLGGHSSLLLLKIPTIEIGFIVATLMFMLLLYSIFRSGRF

Crispr_ID: NC_021171_6

• CRISPR_ID: NC_021171_6
• CRISPR_location: 2712752-2712846
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3

Consensus repeat of NC_021171_6

Consensus_repeat	Method
CCGTGTCCTGGATAACCTCCCAT	CRISPRCasFinder

spacers of NC_021171_6

>6.1|2712775|49|NC_021171|CRISPRCasFinder
GCTGCCAAAACCTCCGTGTCCTGGATAACCTCCCATGCCACCGTACCCG

CRISPR arrays and Neighbor proteins around NC_021171_6

CRISPR arrays

The CRISPR arrays of NC_021171_6

>merge|NC_021171|6|2712752-2712846|CRISPRCasFinder
CCATGTCCTGGATAACCCATCGGGCTGCCAAAACCTCCGTGTCCTGGATAACCTCCCATGCCACCGTACCCGCCGTGTCCTGGATAACCTCCCAT

>NC_021171|6|5|2712752-2712846|CRISPRCasFinder
CCATGTCCTGGATAACCCATCGG	GCTGCCAAAACCTCCGTGTCCTGGATAACCTCCCATGCCACCGTACCCG
CCGTGTCCTGGATAACCTCCCAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_187292103.1|2722066_2722267_+|spore-germination-protein	unknown	unknown	gnl|CDD|371190
NC_021171.1|WP_015594259.1|2703512_2705783_-|hydantoinase-B/oxoprolinase-family-protein	unknown	unknown	gnl|CDD|223224
NC_021171.1|WP_015594272.1|2720459_2721911_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NC_021171.1|WP_015594263.1|2711734_2711935_-|cold-shock-protein	unknown	unknown	gnl|CDD|224197
NC_021171.1|WP_015594258.1|2702984_2703485_-|acetone-carboxylase-subunit-gamma	unknown	unknown	gnl|CDD|226994
NC_021171.1|WP_015594267.1|2715953_2716292_+|hypothetical-protein	unknown	unknown	gnl|CDD|378946
NC_021171.1|WP_015594261.1|2708226_2710245_+|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225822
NC_021171.1|WP_041580509.1|2712214_2712400_+|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_015594270.1|2719378_2719606_-|hypothetical-protein	unknown	unknown	unknown
NC_021171.1|WP_083935098.1|2701024_2702707_-|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl|CDD|223587
NC_021171.1|WP_041580510.1|2713962_2715651_-|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|223733
NC_021171.1|WP_015594271.1|2719719_2720331_-|amino-acid-transporter	unknown	unknown	gnl|CDD|224198
NC_021171.1|WP_041580508.1|2705803_2707951_-|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl|CDD|223223
NC_021171.1|WP_041580511.1|2717127_2718513_-|peptidase-S8	unknown	unknown	gnl|CDD|173810
NC_021171.1|WP_015594265.1|2713027_2713834_-|adenosylmethionine-decarboxylase	unknown	unknown	gnl|CDD|235480
NC_021171.1|WP_015594255.1|2698893_2700255_-|PFL-family-protein	unknown	unknown	gnl|CDD|180009
NC_021171.1|WP_015594256.1|2700269_2700545_-|ACT-domain-containing-protein	unknown	unknown	gnl|CDD|178923
NC_021171.1|WP_015594268.1|2716446_2717076_+|ribonuclease-H-family-protein	unknown	unknown	gnl|CDD|260015
NC_021171.1|WP_144061473.1|2710512_2711433_-|DUF1002-domain-containing-protein	unknown	unknown	gnl|CDD|377628
NC_021171.1|WP_051120155.1|2718749_2719298_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380315

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_021171.1|WP_083935098.1|2701024_2702707_-|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	4.1e-12	40.5	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_187292103.1|2722066_2722267_+|spore-germination-protein	gnl|CDD|371190	pfam10676, gerPA, Spore germination protein gerPA/gerPF. This is a bacterial family of proteins that are required for the formation of functionally normal spores. Proteins in this family may be involved in establishing normal coat structure and/or permeability which could control the access of germinants to their receptor.	0.00263287
NC_021171.1|WP_015594259.1|2703512_2705783_-|hydantoinase-B/oxoprolinase-family-protein	gnl|CDD|223224	COG0146, HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	5.85745e-160
NC_021171.1|WP_015594272.1|2720459_2721911_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.62968e-143
NC_021171.1|WP_015594263.1|2711734_2711935_-|cold-shock-protein	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.03743e-32
NC_021171.1|WP_015594258.1|2702984_2703485_-|acetone-carboxylase-subunit-gamma	gnl|CDD|226994	COG4647, AcxC, Acetone carboxylase, gamma subunit [Secondary metabolites biosynthesis, transport, and catabolism].	8.45702e-74
NC_021171.1|WP_015594265.1|2713027_2713834_-|adenosylmethionine-decarboxylase	gnl|CDD|235480	PRK05462, PRK05462, adenosylmethionine decarboxylase.	0
NC_021171.1|WP_015594261.1|2708226_2710245_+|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	1.08296e-152
NC_021171.1|WP_144061473.1|2710512_2711433_-|DUF1002-domain-containing-protein	gnl|CDD|377628	pfam06207, DUF1002, Protein of unknown function (DUF1002). This protein family has no known function. Its members are about 300 amino acids in length. It has so far been detected in Firmicute bacteria and some archaebacteria.	4.97805e-84
NC_021171.1|WP_083935098.1|2701024_2702707_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	4.37817e-154
NC_021171.1|WP_041580510.1|2713962_2715651_-|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	7.2812e-160
NC_021171.1|WP_015594271.1|2719719_2720331_-|amino-acid-transporter	gnl|CDD|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.73895e-63
NC_021171.1|WP_041580508.1|2705803_2707951_-|hydantoinase/oxoprolinase-family-protein	gnl|CDD|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	7.5161e-170
NC_021171.1|WP_041580511.1|2717127_2718513_-|peptidase-S8	gnl|CDD|173810	cd07484, Peptidases_S8_Thermitase_like, Peptidase S8 family domain in Thermitase-like proteins. Thermitase is a non-specific, trypsin-related serine protease with a very high specific activity. It contains a subtilisin like domain. The tertiary structure of thermitase is similar to that of subtilisin BPN'. It contains a Asp/His/Ser catalytic triad. Members of the peptidases S8 (subtilisin and kexin) and S53 (sedolisin) clan include endopeptidases and exopeptidases. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53 the it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	2.58471e-132
NC_021171.1|WP_015594256.1|2700269_2700545_-|ACT-domain-containing-protein	gnl|CDD|178923	PRK00194, PRK00194, ACT domain-containing protein.	6.50197e-38
NC_021171.1|WP_015594255.1|2698893_2700255_-|PFL-family-protein	gnl|CDD|180009	PRK05313, PRK05313, hypothetical protein; Provisional.	0
NC_021171.1|WP_015594268.1|2716446_2717076_+|ribonuclease-H-family-protein	gnl|CDD|260015	cd13935, RNase_H_bacteria_like, RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. This family includes bacterial ribonuclease H (RNase H) enzymes. RNases are divided into two major families, Type 1 and Type 2, based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication, repair and transcription. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as an anti-HIV drug target because RNase H inactivation inhibits reverse transcription.	2.30224e-67
NC_021171.1|WP_015594267.1|2715953_2716292_+|hypothetical-protein	gnl|CDD|378946	pfam12788, YmaF, YmaF family. This family of proteins contain 6 HXH motifs and is named after the B. subtilis YmaF protein. It seems likely that these are involved in metal binding. The function of this protein is unknown.	1.56084e-10
NC_021171.1|WP_051120155.1|2718749_2719298_+|nitroreductase-family-protein	gnl|CDD|380315	cd02138, TdsD-like, nitroreductase similar to Burkholderia pseudomallei TdsD. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to Burkholderia pseudomallei TdsD, may be involved in the processing of organosulfur compounds. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	1.04279e-77

Protein sequences

>NC_021171.1|WP_041580509.1|2712214_2712400_+|hypothetical-protein
MKHLNNLYNAGETVNVKATGETVTILKWKYVKNMKRFSYILTEYPGTFYFEEELTRNQLSE
>NC_021171.1|WP_015594263.1|2711734_2711935_-|cold-shock-protein
MENGKVKWFNAEKGFGFIERDGGEDVFVHFSAIQGEGFKTLEEGQAVTFDVEKGARGPQAANVRKA
>NC_021171.1|WP_144061473.1|2710512_2711433_-|DUF1002-domain-containing-protein
MIMKKIIKWVALAAVLTLTLSIGSKALASDNSSSEESINEKYGLPIVVYGAALSPSQKDEVRSLLGVTDPSKVKEITVTGEDIYTYIKGDRNSNMYSSAKITRKDSGEGLVIKQVTPENITEVTDEMYANALLTAGINDAVVEVASPIKVSGHSALVGIYKAYDAGEGAGLNKDRTEVANQELNLATDLAKKEGLDKDKVSELLTEIKKEIADQNPASKEDIAKIIDDKLKELGIQLSDQDRQLLIDLFEKMRGLNINFDNVQSQLDNLSKDITNRIEQAIGDKGFLQKVATFFKELITSIKNIFS
>NC_021171.1|WP_015594261.1|2708226_2710245_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MGNNFISIFSTRNLPDRTRELATLWENFVSKAWGEVSPNKIRKNVLESWKRCQEINVNPSQLQTNTFLTDMGLKQVLEKSELYKISKPIIDDFYQKMFGTGYLITLTNRNGYIIYLKGEKQEWREAEKMNFIPGMDWSEKSAGTNAIGTSLATRTPIQIFSAEHFCLGCHPWTCSSAPITHPFTKEMIGAVDFTGFWGNAQPHTLGLAVSLAQIIEKQFAEIYMKVNYYLTESFFQSVNKWKKDHVLVLNHTFFTVKSSELLARYFKLTPGTDLRLNLSFHSLINELNQALPGKDEVYPAIEINIGDFQVHSIEKLHYMENLVGYRVIFIDKNKKALRSTSRLRLKDGSWEDVIGVSEGFLDTLYKCQKAAMSNVPILLLGESGTGKEKIAQSIHKSSHRCDQPFLAINCGAIQKELIGSELFGYDRGAFTGASKEGKKGKFEEAHGGTLFLDEIGEMPLELQVHLLRVLQEKEITRIGSSKPISVNVRIIAATNKNLYDLCNKGLFRQDLFFRLNVVSVNIPPLRERKDDLTLIVEYFLKQLTNKYEKEQLSLSEDIFKYFLEYPWPGNIRELQNVLEHAVIFSDSSLITFEDLPAYLIEYGISNSSTNQKPKLSLIHDEEQKVLIRLLEETNWNLSAVAKRLNIARSTLYRRLKKYQLVQNRSLEKGSVY
>NC_021171.1|WP_041580508.1|2705803_2707951_-|hydantoinase/oxoprolinase-family-protein
MDTMTTRKAQILAIDAGGTMTDTFIIDDNGDFVVGKAQSTPEDESIGLLNSARDALTYWETTVEAEFPKLLAGVYSGTAMLNRLVSRKGRKVGLIVNKGMEDFHRMGRAIQAYLGYSYSDRLHLNTHRYDPPLVPRELTKGITERVDIFGNVVIPLYEHEVEGAVQELLEQNVEAIVISLLHSYKYPAHERKIRDIAIATLKKAGKDIPTFASVDYYPVRKETHRTNTTIIEAYAADPSRETLNKIDDMLREHGTTFDLRVMASHGGTISTQANELARTLVSGPIGGVVGAKYLGEALGIPNIACSDIGGTSFDMALITQGDLSINTSPDMARLVLSLPLVAMDTVGAGAGSYVRIDPNFKSLTLGPDSAGSKVGVCYPEGGVETVTVSDCHVVLGLINPDNFLGGEVKLDPVRAYEAVKKQIADPLGLSIEDAAYGVIDLLESQLRNYLESMILGKGYSPSQYVCFSYGGGGPLHTAGYTKGLGFEEVLVPAWAAGFSAFGCGAADFEYRYDKTLDINVDQIAGDDIKLMAGKELQGAWDELMEKVAAEFEKNKFDRKDVDFRLYFRMQYQGQLNDLEIEAPIKSFKSVLDWENLVEAFEDTYTRIYAKAAKSPELGYSITGAIIRGIVDVAKPRIPEEPLLGEKPAGDAFLGKRNVYWKGEWIKANIWEMEKLNPGNKIGAFSILESPATTFVIPPGFEAYLDEHRIFHLKEF
>NC_021171.1|WP_015594259.1|2703512_2705783_-|hydantoinase-B/oxoprolinase-family-protein
MNRTEKGLQSQKNIGWDGKTLQQMRTEVDEVSRETGHYAGLRTLPLKETDPIRYEKIFSKLRGGVVHARETAKKVAASPIVEQEGELCFTLYTPEADSVVTSTGIIIHVGTMGSAIKYMIKNDYESNPGIEDGDIFCNNDCQIGNVHPCDVHTIVPIFHNEEVIGWVGGVTHVIDVGATAPGSMTVGPVSRYDDGYQVACRKIGKSDTLLKDWVIESQRSVRTTKYWLLDERTRIAGCHMIRDLVLNIVKEEGIDTYKHFIREVIEDGRRGFVNQVKSMLIPGKYRQVSFVDVPYKDLDVPPYARVNTIMHAPTEMTVHKDGKFQINFEGVNRWGWHSYNATPVAITSGIWVMMSQTLIPNDRVNDGALYASHFDLPYGSWLNPDDIRTAHSYAWHFLVSAWSPLWRALSRNYFARGYLEEVNAGNANTSNWLQGGGVNQFGENHAVNSFESAAEGIGASAVRDGISHAAAIWNPEGDMGDMEIWELAEPLLYLGRSIKPNTAGYGKYRGGSGYETLRMVYGAKDWTMFFMGNGYMSSDCGLMGGYPAASGYRFEAHGTNLKDRIDKKLPIPTGGDTDPDNPEYEQLVDATEIIRDKQSITTETIFENYDLYLNYLRGGPGFGDPLERSPKSIEEDLNDGHLLPRFAEKVYGAVINESQKGNFIVDEKATEERRNQIKRARLKRGVPVSEWMKQERQTIINKEAAVQVRHMYASSFALSETFAAEFKEFWDLPKEWKMTEAELGVPIFGAKINHNQ
>NC_021171.1|WP_015594258.1|2702984_2703485_-|acetone-carboxylase-subunit-gamma
MTQYDRKTIEELIDGTIDFYKLKEMLSSFKDADRFEKYVSILQERVAWKDPILLPAGLHLYIVQKANGDRIVKCDCGHEFCQASDNWKLHSLINVRDTQEKLSDLYPKMLAPDPEWQVIREYYCPECAAQLEVEAVTPWYPILKDFEPDIDTFYTEWLKKPLPVAK
>NC_021171.1|WP_083935098.1|2701024_2702707_-|DEAD/DEAH-box-helicase
MPDFLSMGISEMLVEKLQESGVVTPTPIQEQAIPYVMKGNDIIAQAQTGTGKTFAFILPILEHLDPEASHVQALIVTPTRELALQITGEFKKLINDLPGIDVLAVYGGQDVDKQLKKLKKNVQIVVSTPGRLLDHIRRGTVNLSEISSLVLDEADQMLQIGFLNEVEEIIDQTPASRQTMLFSATMPPEIRTLARKHMREPKYIQVEKTQGPAQTVNQLAIHTVDRAKQATLIGLIEAHRPFLAVIFCRTKRRVSKLYEALRSHGYKCDELHGDLSQAKREQVMKRFRDAEVQLLIATDVAARGLDVEGVTHVYNYDIPLDSESYIHRIGRTGRAGMTGMAITLYASKDRPLLDLIEKELNLSIEKQNLGNMEKTDDETVDRPNRSSSSQMERRGNRKGRSGRTEGPRRQGDKRSNKFEDPNITRDRRGNLLKDSRSRTEVKGKKSEVPRQPRDRNEVRSEGARPARNRNEGARPQRSRNEAKSADSRPQRSRNEVKSADSRPQRSRNEVKSADSRPQRSRNEVKSAGSSPSRGRNEVKSQISRPSKKRNDFKSQGPNNR
>NC_021171.1|WP_015594256.1|2700269_2700545_-|ACT-domain-containing-protein
MNKRRAVVSVVGKDQVGIIAKVTNILSENSINILDISQTILQDFFTMMMIVDVSGTENLDVLQKHFDEVSEELSLKINIQLEEIFQAMHRI
>NC_021171.1|WP_015594255.1|2698893_2700255_-|PFL-family-protein
MNIAIQEMMETIRMVQMENLDIRTVTMGINLHDCADSDFEKMNDRVYDKIVNYASRLKEVAEEVEKEFGIPIINKRISITPIAEILGNATKDQAIILAKTLDRAAVILGIDFIGGYSALVHKGIAKGDQTLLDALPEALSVTERVCASVSVATTRTGINMDAVSKLGVIIKEAAERTKDQNGLACAKLVVFCNPVEDNPFMAGAFHGSGEGEVVLNVGVSGPGVVLNALKRHPEADLGEVSEVIKKTAFKITRAGELIGRVVAERLGVPFGIMDLSLAPTNAINDSVAEILEEIGLERVGTHGTIAALALMNDAVKKGGAMASSYVGGLSGAFIPVSEDNGMIRGILDKSLTLSKLEAMTCVCSVGLDMIAITGDVTPSTLSAIIADEAAIGMINKKTTAVRVIPVPGKIEGDLVEFGGLLGRAPVMGVNPFSSEKFIRRGGRIPAPLQALIN
>NC_021171.1|WP_015594265.1|2713027_2713834_-|adenosylmethionine-decarboxylase
MTLSPEQRVELYGFNNLTKTLSFNMYDICYTTTKSEREAYFHYIDDQYNADRLTNILSNVSDIIGAHVLNIAKQDYVPQGSSVTFLVSEGPVIEVPNGSFAESPGPLPDAVVLALDKSHITVHTYPESHPDEGISTFRADIDVSTCGEISPLKALNYLIHSFDTDIMTIDYRVRGFTRDISGHKLFIDHEISSIQNYIPDEIKNIYHMIDVNVYQENIFHTKCKLREFDLNNYLFGYTKEKLSSKEVEEITEKLNLEMDEIFYGKNIQ
>NC_021171.1|WP_041580510.1|2713962_2715651_-|AarF/ABC1/UbiB-kinase-family-protein
MIRKRFRHIQRYREIVNAFIRYGFGFVIKEMGLIELLSMPKRLFVEVNPETETQNTSTGERIKMFLEELGPTFVKMGQVASTRYDLIPSEIVKELENLQDNAQQFPFEVVQETIEKELGQPIGQVFNEFCEIPIAAASIGQVHYAILKTGEKVAVKVQRPNMRSIIDTDLEILQDLAILAEQRLAWAARYQIRDIVDEFSKSLREEVDYSIEGRNSERIAKQFIDDPKVVIPKVFWEYSTKKILTMEFVEGTKLYETEMLHQMGNDNKILAKRIVDSILHQVLIEGYFHGDPHPGNILALPNDVIIFLDFGMVGRLTPDMKHHIASLVIALMRQNTDDVIKAITRMGIVPSDINISMLRGDVEKLNETYYDVPLSKVSLGQVVNDLFLVAYRHNIRIPPDLTLLGKTLLTMEGIVVKLDPEISILKVAEPFGRRLLMERYDPKKVVGNLWHQIVDLGEFVKDLPKGLKELTLLFKNGKVRQEISFPEIDLILAKLNQISNRISFSIGLLSFSIIICGLIIGSSLGGHSSLLLLKIPTIEIGFIVATLMFMLLLYSIFRSGRF
>NC_021171.1|WP_015594267.1|2715953_2716292_+|hypothetical-protein
MMKVGKDDFVTGFVPHHTHGSVDYTSVNAGHVHQCLDVTSPPIQTQDGSHIHHTEGYVVFENGHTHHYKANSGPAIPVGNGMHVHYYDFNTTENDGHHHRVKGVDQPAPGNK
>NC_021171.1|WP_015594268.1|2716446_2717076_+|ribonuclease-H-family-protein
MADKKKYYVVWAGRNTGVFRSWADCEKQTKGFQGASFKSFPSLEEANQAYSNGKPNYSFSKVKNATKKSGSSEVTVFNPNSISVDAACSGNPGMMEYQGVSTKTGEVLFHFGPTLGTNNIGEFLAIVHALAMLKKQGLDTDIYSDSVTALSWVRNKKANTSLVRNKETETVWNLIERAEAWLKENRYPNKILKWDTNKLGEIKADFGRK
>NC_021171.1|WP_041580511.1|2717127_2718513_-|peptidase-S8
MRKITKPIVVIIVSSVILISVISISRMRSPERTERTTIQQTENKTDPRFLYDMTKIQNVENMPHLLRVNSLEMGETIKGHLRKDPSVHIIQHPENNESHFNKSEVIVKFKQHPNATELDKMSKDIHGGVVKNLDSTIVFRSEKLTTSELTDYFKNLSNVEFAEPNYLYLQNQIGPNDLLYREQYQWNLPSIRAESGWDLSRGKEDVVIAIVDTGVDLNHPDLKNRLTEGFNVIENNNYPDDDNGHGTHVAGIIASETNNQEGVAGITWFNKIMPVKAMEAKGYGTSFDIAKGIIWAVNHGADVINLSLGNYQGSAVMKQAVEYAYKKDVVLISASGNDNSSQPSFPASYPEVLAVSAVDYNGNRATFSNYGDYVDVTAPGVEIPSTYFNRQYAALSGTSMASPHVAGLAGLIRSENPKLTNKEVMNIIKKTAFDLGDKGNDIEFGGGLIDVRKALEAAKPK
>NC_021171.1|WP_051120155.1|2718749_2719298_+|nitroreductase-family-protein
MDPVYLNRWSPRSFLEKDVPNDVLLSIFEAARWAPSAYNLQPWRFIISRDQESRENFYPFIGEFNRKWCEKAPVLAVIISKTTSENGPIPSHSFDTGAAWGYLSLEATKKGLITHPMTGFDFEKAREVLNIPEDYATNALIAIGYQGKAEELPEPLRERELPSSRNPLDESLFEGNFGSPLK
>NC_021171.1|WP_015594270.1|2719378_2719606_-|hypothetical-protein
MKPFEIKNMIIDDEFAGEESVTADFTHKNKEYSITFKKADLEIVNIWVFENGTSFPANLTDNIIESIREDVKKRI
>NC_021171.1|WP_015594271.1|2719719_2720331_-|amino-acid-transporter
MFEAILHGLILAFGLILPLGVQNVFVFNQGATQLKFNRTLPVIITASICDTILISLAVFGVTFIILGIYWIKVVLLIVGVIFLVYMGYVTWRSKPNLSSAEEKTLSSKKQIVFALSVSLLNPHAIMDTIGVIGTNSLTYSGPRKLAFTLACIVTSWVWFFSLALAGRQVGRLNNSVSFITILNKLSALIMWGTSIYLIYILNL
>NC_021171.1|WP_015594272.1|2720459_2721911_+|PLP-dependent-aminotransferase-family-protein
MSKEWVINKLSLIPLHQQIYEYIKRKIMNGEWSIGTRIPSQRELAKKFQVNRSTIVYALGELAADGLIESNAGKGTVVINNTWSLLASTPPPDWNSYVKSGSYQPNIQMIQEINKAETNPDITRLGTGELSPELLPVEKMKQMFQTHSSKMLSLGYSEPKGDIYLREIISDYLKTKGIIASPSAILIVSGGLQALQLISLGLLQRSSTVFLESPSYLNSVHVFQSAGMNLFGIPLNNEGILIDQIGKLKRQHNGALLYTIPSFHNPTGILMSSNRRMELLNVCKSERLPIIEDDVYGDLWFESAPPNPIKALDDQGLVLYIGSMSKTLGPGLRIGWIVGPEPVVERLADIKMQTDYGSSSLSQYAVAEWISSGLYDEHIKKIRTELKFRRDFTIDVLNNHLRDLSSWSIPAGGFYIWISINKQISIRNLFEKALKEGILLNPGNIYDRNDQQHLRLSYSYAPLPQLKRALIRLSELIQELITY
>NC_021171.1|WP_187292103.1|2722066_2722267_+|spore-germination-protein
MEYTINITHFMVNSLANNANINIGPTYQNSHTANSKTIGTNLNFGDNGSKLSEIFNSGNNPEHHQG

Crispr_ID: NC_021171_7

• CRISPR_ID: NC_021171_7
• CRISPR_location: 2771384-2771977
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 9 spacers

Consensus repeat of NC_021171_7

Consensus_repeat	Method
TACTCGNCGCTCTACNCGTCGCTCTACTCG	CRT

spacers of NC_021171_7

>7.1|2771414|18|NC_021171|CRT
TCGGTCTACTCGCCGCAC
>7.2|2771462|30|NC_021171|CRT
CCGATCTACTCGTCGGTCTACTCACCGATC
>7.3|2771522|66|NC_021171|CRT
CCGCTCTTCTCGTCGCTCTTCTCGTCGCTCTTCTCGCCGCACTACCCGTCGCTCTTCTCGTCGCTC
>7.4|2771618|54|NC_021171|CRT
TCGGTCTACTCGTCGCTCTTCTCGTCGCTCTACTCGTCGGTCTTCTCGCCGCTC
>7.5|2771702|18|NC_021171|CRT
TCGCTCTACTCGTCGCTC
>7.6|2771750|30|NC_021171|CRT
CCGCTCTACTCGTCGGTCTACTCGCCGCTC
>7.7|2771810|18|NC_021171|CRT
CCGGTCTACTCGTCGCTC
>7.8|2771858|42|NC_021171|CRT
TCGGTCTACTCGTCGGTCTTCTCGCCGCTCTACTCGTCGGTC
>7.9|2771930|18|NC_021171|CRT
TCGGTCTACTCGCCGCTC

CRISPR arrays and Neighbor proteins around NC_021171_7

CRISPR arrays

The CRISPR arrays of NC_021171_7

>merge|NC_021171|7|2771384-2771977|CRT
TACTCGTCGCTCTACCCGTCGTACTACTCGTCGGTCTACTCGCCGCACTACTCGCCGCTCTACCCGTCGCTCTACTCGCCGATCTACTCGTCGGTCTACTCACCGATCTACTCGTCGCTCTACTCGTCGCTCTTCTCGCCGCTCTTCTCGTCGCTCTTCTCGTCGCTCTTCTCGCCGCACTACCCGTCGCTCTTCTCGTCGCTCTACTCGTCGATCTACTCGCCGCTCTTCTCGTCGGTCTACTCGTCGCTCTTCTCGTCGCTCTACTCGTCGGTCTTCTCGCCGCTCTACCCGTCGCTCTACCCGTCGCTCTTCTCGTCGCTCTACTCGTCGCTCTACCCGTCGCTCTACTCGTCGCTCTACTCGCCGCTCTACTCGTCGGTCTACTCGCCGCTCTACTCGCCGCTCTACTCGTCGCTCTACTCGCCGGTCTACTCGTCGCTCTACTCGCCGGTCTACTCGTCGCACTACTCGTCGGTCTACTCGTCGGTCTTCTCGCCGCTCTACTCGTCGGTCTTCTCGCCGCTCTACTCGTCGCTCTACCCGTCGGTCTACTCGCCGCTCTACTCGTCGATCTACCCGTCGCTCTACTTC

>NC_021171|7|2|2771384-2771977|CRT
TACTCGTCGCTCTACCCGTCGTACTACTCG	TCGGTCTACTCGCCGCAC
TACTCGCCGCTCTACCCGTCGCTCTACTCG	CCGATCTACTCGTCGGTCTACTCACCGATC
TACTCGTCGCTCTACTCGTCGCTCTTCTCG	CCGCTCTTCTCGTCGCTCTTCTCGTCGCTCTTCTCGCCGCACTACCCGTCGCTCTTCTCGTCGCTC
TACTCGTCGATCTACTCGCCGCTCTTCTCG	TCGGTCTACTCGTCGCTCTTCTCGTCGCTCTACTCGTCGGTCTTCTCGCCGCTC
TACCCGTCGCTCTACCCGTCGCTCTTCTCG	TCGCTCTACTCGTCGCTC
TACCCGTCGCTCTACTCGTCGCTCTACTCG	CCGCTCTACTCGTCGGTCTACTCGCCGCTC
TACTCGCCGCTCTACTCGTCGCTCTACTCG	CCGGTCTACTCGTCGCTC
TACTCGCCGGTCTACTCGTCGCACTACTCG	TCGGTCTACTCGTCGGTCTTCTCGCCGCTCTACTCGTCGGTC
TTCTCGCCGCTCTACTCGTCGCTCTACCCG	TCGGTCTACTCGCCGCTC
TACTCGTCGATCTACCCGTCGCTCTACTTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_144061477.1|2772082_2772367_-|hypothetical-protein	unknown	unknown	gnl|CDD|173502
NC_021171.1|WP_015594322.1|2780275_2781568_-|M20-family-metallo-hydrolase	unknown	unknown	gnl|CDD|236456
NC_021171.1|WP_015594307.1|2764106_2765651_+|cation-acetate-symporter	unknown	unknown	gnl|CDD|271374
NC_021171.1|WP_015594310.1|2768353_2769427_-|hypothetical-protein	unknown	unknown	gnl|CDD|240427
NC_021171.1|WP_187292104.1|2776021_2777863_-|SEC-C-domain-containing-protein	unknown	unknown	gnl|CDD|376935
NC_021171.1|WP_015594321.1|2778993_2780244_-|ArgE/DapE-family-deacylase	unknown	unknown	gnl|CDD|349869
NC_021171.1|WP_041581090.1|2773708_2774215_-|mismatch-specific-DNA-glycosylase	unknown	unknown	gnl|CDD|381679
NC_021171.1|WP_144061587.1|2778075_2778936_+|thermonuclease-family-protein	unknown	unknown	gnl|CDD|214615
NC_021171.1|WP_015594316.1|2773197_2773638_-|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NC_021171.1|WP_015594318.1|2774657_2775770_+|radical-SAM/CxCxxxxC-motif-protein-YfkAB	unknown	unknown	gnl|CDD|275271
NC_021171.1|WP_015594303.1|2759862_2760702_-|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl|CDD|181221
NC_021171.1|WP_015594305.1|2762360_2763503_+|IscS-subfamily-cysteine-desulfurase	unknown	unknown	gnl|CDD|179511
NC_021171.1|WP_015594304.1|2760655_2762254_-|L-aspartate-oxidase	unknown	unknown	gnl|CDD|236147
NC_021171.1|WP_015594306.1|2763741_2764086_+|DUF485-domain-containing-protein	unknown	unknown	gnl|CDD|377315
NC_021171.1|WP_015594314.1|2772521_2772950_-|cell-wall-hydrolase	unknown	unknown	gnl|CDD|226296
NC_021171.1|WP_015594311.1|2769549_2770653_-|CotH-kinase-family-protein	unknown	unknown	gnl|CDD|227642
NC_021171.1|WP_144061479.1|2781524_2782859_-|allantoinase	unknown	unknown	gnl|CDD|235732
NC_021171.1|WP_083935189.1|2766193_2767522_+|arsenic-transporter	unknown	unknown	gnl|CDD|238538
NC_021171.1|WP_015594302.1|2758732_2759836_-|quinolinate-synthase-NadA	unknown	unknown	gnl|CDD|236489
NC_021171.1|WP_015594309.1|2767564_2768239_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_144061477.1|2772082_2772367_-|hypothetical-protein	gnl|CDD|173502	PTZ00266, PTZ00266, NIMA-related protein kinase; Provisional.	0.000273228
NC_021171.1|WP_015594307.1|2764106_2765651_+|cation-acetate-symporter	gnl|CDD|271374	cd11480, SLC5sbd_u4, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	0
NC_021171.1|WP_015594310.1|2768353_2769427_-|hypothetical-protein	gnl|CDD|240427	PTZ00470, PTZ00470, glycoside hydrolase family 47 protein; Provisional.	0.00194547
NC_021171.1|WP_187292104.1|2776021_2777863_-|SEC-C-domain-containing-protein	gnl|CDD|376935	pfam02810, SEC-C, SEC-C motif. The SEC-C motif found in the C-terminus of the SecA protein, in the middle of some SWI2 ATPases and also solo in several proteins. The motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain.	1.74206e-11
NC_021171.1|WP_015594321.1|2778993_2780244_-|ArgE/DapE-family-deacylase	gnl|CDD|349869	cd02697, M20_like, M20 Zn-peptidases include exopeptidases. Peptidase M20 family; uncharacterized subfamily. These hypothetical proteins have been inferred by homology to be exopeptidases: carboxypeptidases, dipeptidases and a specialized aminopeptidase. In general, the peptidase hydrolyzes the late products of protein degradation in order to complete the conversion of proteins to free amino acids. Members of this subfamily may bind metal ions such as zinc.	1.53009e-157
NC_021171.1|WP_041581090.1|2773708_2774215_-|mismatch-specific-DNA-glycosylase	gnl|CDD|381679	cd10028, UDG-F2_TDG_MUG, Uracil DNA glycosylase family 2, includes thymine DNA glycosylase, mismatch-specific uracil DNA glycosylase and similar proteins. Uracil DNA glycosylase family 2 consists of thymine DNA glycosylase (TDG), which removes uracil and thymine from G:U and G:T mismatches in double-stranded DNA. It includes mismatch-specific uracil DNA glycosylase (MUG), the prokaryotic homolog of TDG. Escherichia coli MUG is highly specific to G:U mismatches but also repairs G:T mismatches at high enzyme concentration. Uracil-DNA glycosylases (UDGs) initiate repair of uracils in DNA. Uracil in DNA can arise as a result of misincorporation of dUMP residues by DNA polymerase or via deamination of cytosine. Uracil in DNA mispaired with guanine is one of the major pro-mutagenic events, causing G:C->A:T mutations. Thus, UDG is an essential enzyme for maintaining the integrity of genetic information. UDGs have been classified into various families on the basis of their substrate specificity, conserved motifs, and structural similarities. Although these families demonstrate different substrate specificities, often the function of one enzyme can be complemented by the other..	1.09873e-81
NC_021171.1|WP_144061587.1|2778075_2778936_+|thermonuclease-family-protein	gnl|CDD|214615	smart00318, SNc, Staphylococcal nuclease homologues.	5.61913e-39
NC_021171.1|WP_015594316.1|2773197_2773638_-|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	3.91027e-59
NC_021171.1|WP_015594318.1|2774657_2775770_+|radical-SAM/CxCxxxxC-motif-protein-YfkAB	gnl|CDD|275271	TIGR04478, radical_SAM_superfamily_domain_protein, radical SAM/CxCxxxxC motif protein YfkAB. Members of this highly conserved family in some Firmicutes have an N-terminal radical SAM domain (pfam04055) and a C-terminal pfam08756 domain with a CxCxxxxC motif that suggests binding to an additional metallocluster. It appears all correct sequences in this family are about 370 amino acids in length, containing the YfkA and YfkB regions originally reported as separate ORFs in Bacillus subtilis. Partial Phylogenetic Profiling shows occurrences almost exclusively in the Bacilli, with very few examples of either lateral transfer or gene loss. The essentially monophyletic distribution suggests a housekeeping function. Members have no well-conserved gene neighborhood. The function is unknown. [Unknown function, Enzymes of unknown specificity].	0
NC_021171.1|WP_015594303.1|2759862_2760702_-|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl|CDD|181221	PRK08072, PRK08072, carboxylating nicotinate-nucleotide diphosphorylase.	5.23617e-164
NC_021171.1|WP_015594305.1|2762360_2763503_+|IscS-subfamily-cysteine-desulfurase	gnl|CDD|179511	PRK02948, PRK02948, IscS subfamily cysteine desulfurase.	1.78546e-158
NC_021171.1|WP_015594304.1|2760655_2762254_-|L-aspartate-oxidase	gnl|CDD|236147	PRK08071, PRK08071, L-aspartate oxidase; Provisional.	0
NC_021171.1|WP_015594306.1|2763741_2764086_+|DUF485-domain-containing-protein	gnl|CDD|377315	pfam04341, DUF485, Protein of unknown function, DUF485. This family includes several putative integral membrane proteins.	3.98791e-25
NC_021171.1|WP_015594314.1|2772521_2772950_-|cell-wall-hydrolase	gnl|CDD|226296	COG3773, SleB, Cell wall hydrolyses involved in spore germination [Cell envelope biogenesis, outer membrane].	5.80148e-43
NC_021171.1|WP_015594311.1|2769549_2770653_-|CotH-kinase-family-protein	gnl|CDD|227642	COG5337, CotH, Spore coat assembly protein [Cell envelope biogenesis, outer membrane].	1.33153e-115
NC_021171.1|WP_144061479.1|2781524_2782859_-|allantoinase	gnl|CDD|235732	PRK06189, PRK06189, allantoinase; Provisional.	0
NC_021171.1|WP_083935189.1|2766193_2767522_+|arsenic-transporter	gnl|CDD|238538	cd01118, ArsB_permease, Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.	4.77986e-107
NC_021171.1|WP_015594302.1|2758732_2759836_-|quinolinate-synthase-NadA	gnl|CDD|236489	PRK09375, PRK09375, quinolinate synthase NadA.	2.46469e-153
NC_021171.1|WP_015594322.1|2780275_2781568_-|M20-family-metallo-hydrolase	gnl|CDD|236456	PRK09290, PRK09290, allantoate amidohydrolase; Reviewed.	2.10749e-171

Protein sequences

>NC_021171.1|WP_015594311.1|2769549_2770653_-|CotH-kinase-family-protein
MNLDKYTNSNIPLYQLFIHPLDIIELRRDIWCDDPVPAKLTVKKSKYDIDIAYRGSHIRDFDKKSYHVTFFKPATVRNAKEVHLNAEYKDPSLIRNKLSLDFFSDIGLLSPQSRHVFLKINGKNVGVYLELESVDEFFLANRKLPAGAIFYAVDGDANFSLMSDLDKEVKKSLELGYQKKCGTEIDDYYLQEMIIKVNTILRADFEIEIEKYINVDKYLRWLAGVVFTQNYDGFVHNYALYRNGETGQFEIIPWDYDATWGRDVNGKFMDEKYVRIEGFNTLTARILDVDSFRKRYKTLLEQILNQQFNIDYMEPIIQTMHQNIRPFVLQDPYEREKIEKFDKEPEFISRFIEGRSKYIKSKLYKLD
>NC_021171.1|WP_015594310.1|2768353_2769427_-|hypothetical-protein
MISENVDGNDLSESYHSFLESLKGKVVTIYRGGPESKTGKLLDVKSDYVALYAQNNNNNNNNNNNNNNNNNQKNGQQNNNQNNDQQNNNQNTVVYYQARHVKSISEDSKTNSTQVTETNEDTVEFFEAANFSQLLNHLLKETIQINQGGPETKYGTLLGVANGFVILYTEDDGIVYFNIDHVKSVSKYQTNDDNNNNNNNNQNNNQNNNQQIITYPEFLEAEDFHGVFSHMAHKWVSINRGGPEAMEGVLVENAGGHYTLVSNEEVLRIHPYHIRSISSGPKGSLSQNNQNENSEENQSNDQSTQNSNNAKNERNENKNKDKNKEKESRKTSRRSESKEYQREKVVKTIDYVWKGSK
>NC_021171.1|WP_015594309.1|2767564_2768239_-|hypothetical-protein
MTGIKSYLNMEVEIEISGRTFFTGILLDIGLDILVLFDGQEYLYIPLMHLHNIKERTIKINEEGTVQPTGKMPFQNEKETISYRKILNNAKGQFLEVFVTGNRSIHGYITSVLNDYIVFYSPVYKTLFISMQHLKWLIPYSSQLTPYTLSNAVLPVVPSSIPLSRSFDEQLKKYEGKLLVFDLGDNPNKVGLVKSIHNNIVELITAGGQKIYWKLTHLKTVHIP
>NC_021171.1|WP_083935189.1|2766193_2767522_+|arsenic-transporter
MLSFLLTMTLIFWRPRGINEAIPATIGAIFVLISGSVSIADLGEISSKVSGAAITIISTMVMAIALESFGFFHWVAAKLLIATKNSGIRLFWLTNLLCFMMTLFLNNDGSILITTPILILLLKYIGLKHHQKLPYLISGAIIATASSAPIGVSNIVNLIALKIIGMDLYLHTIMMFVPATTGLLFLSGLLFVTFYKDLPKTLPLLPKRISLFGLQNFHPLQSDPDVAFEKKQTRLMIWVLIFIFIVRISLFVASYIGVSVSLVAALCSIGLLGWRWYILKINPLDMIKKTPWHIFIFAFNMYVIIFGLHNIGLTHLLIEYIKPIVSNSLLHASLIMGTLTAILSNTFNNHPALMISTFALTEMGLDPITMKTIYLANIIGSDIGSLLFPIGTLASLIWMHILKQHNVKITWKQYVKVTILTIPPSMVFTLICLYYWIKLVFY
>NC_021171.1|WP_015594307.1|2764106_2765651_+|cation-acetate-symporter
MNKLAFILFLIIVGLTLVITYFASKRTKTTSDFYTADSSLTGWQNGMAIAGDYMSAASFLGIAGMIALTGFDGFFYSIGFLVAYLVVLYVVAEPLRNLGKYTLADMIAARFNDKKIRGVAALNTMTISIFYMIAQLVGAGGLIKLLLGIDYVYAVLIVGTLMTVYVVFGGMTATSWVQIVKAVLLMVGTFIISMIVFSKFDFNVMKMFTAMKSATPLAGTFLNPGNKFTNPLDTISLNLALVLGTAGLPHILIRFFTVKDSITARKSVVYATWIIGIFYVMTIFLGFGAAAFVGYDNIVAANAAGNMAAPLLAKALGGDFLFAFISAVAFATILAVVAGLVLTAASAFAHDFYSHIVRRGQATEKEQIVAARWASIGVAVLSIILALFAQKMNVAFLVALAFAVAASANLPIILFTIFWKRFNTTGAITGMLVGLITSLVLVAISPNVWSPEAGVAIFVGKPLISLTNPGIISIPVGFIAAIVGTLLSSKKADVKKFDEILVKANTGIHNTLNS
>NC_021171.1|WP_015594306.1|2763741_2764086_+|DUF485-domain-containing-protein
MAVNEKAFNKGFDDNGAELDYSKIVKTASFQKLLRVKRGFIVPMSIFFLVFYFTLPVLTAYSDILNQKAFGDITWAWVFGSAQFIMTWSLCGIYSGKARKFDQMVEGIIEESQN
>NC_021171.1|WP_015594305.1|2762360_2763503_+|IscS-subfamily-cysteine-desulfurase
MKYFDYAATCPLDQDAASVYVKIATEHYGNSQSLHDIGDEASQLLENCRIEFSQMLNAEKEGIFFTSGGSEGNFLAIESLLSGNKKDGNHIITTIAEHSSIQSVIDRLKLNGFRITYLPFNDEGLIEVSEFAQAICEDTIMAVIQHGNSEIGTVQPIVEIGKLCQKHGILLHSDCVQTFGKWNLKQITPYIDSLSLSGHKFYGPKGTGAVYIRPQLTWVPVFPNTTHEKGFRPGTINVAGIAAMTIAAKKANSTLDQDMVHYLNLRKILIDSLGPVSDRIIIHGSIGDQHQLPSIIGMSIIGVEGQWMLLECNRNGFAISTGSACHSGMKSPSQSMIALGLSGKKAKEYFRISLGRDVIEDDIRNLANLFVKTVYSISEN
>NC_021171.1|WP_015594304.1|2760655_2762254_-|L-aspartate-oxidase
MKKADVIIIGSGIAALQMAHHINSNKNVMILTKSNIKDSNSSLAQGGIAASVGKNDHFYYHSKDTMDAGRYHNNEEVVFKITKEAPQLITDLRQKGFSFDEDRLGQMLLGMEGAHSRNRIVHSGGDATGKHVIDFLVDTLKNNISVIEDIFVYELIINEKQQCIGVKGKDSVGNIQYYFSDHTVIATGGCGYLYSLTSNSPNVTGDGIAMAYLAGAEITDIEFIQFHPTMLVKNGQICGLISEAVRGQGAILKTKNGKAIMDDIHPLKDLAPRHIVSQTIFEYLQNGEEIFLDITMIEHFAKKFPSITALCIQNNINLKAGMIPVVPGSHFLMGGVKVDMNCQTNITGLYAIGEVACTGLHGANRLASNSLLEGMYFGKRLAEHINLSTASNEDIQFPLKSKRPIFMPLSFPDKNELRRTMMEQVGIVRNREGLQWQKDWLEGFVQLEQDFGAFDNLSASEIQSTLECLTSLLITTAALERTESRGGHFRSDFPLENDDHWQNKQLIYQYGKGRFEEDEQTKVTSYARAVFS
>NC_021171.1|WP_015594303.1|2759862_2760702_-|carboxylating-nicotinate-nucleotide-diphosphorylase
MNKLKLRAMLEQYFLEDMGERDISTELIFGKEEYGEISFIAKEDGIFCGEEIITVGFGLLSNQNRVELYVHDGNKIEKGQILARVTGNISDLLSGERVILNLVQRMSGVATLTHNAVSKLNGTKTRICDTRKTTPGLRMLEKYAVRIGGGYNHRYGLYDGVMIKDNHISFAGSITKAVVKVREQIGHMVKIEVETETLEQVKEAIASGTDVIMFDNRTPEEIKAWIDLVPDSIITEASGGITLENVASYGSTGVDYISLGFLTHSAKAIDISVKVSITS
>NC_021171.1|WP_015594302.1|2758732_2759836_-|quinolinate-synthase-NadA
MNLLDTLVKTTSIPDYFRFMNREELEERVREVKARLGKKLFIPGHHYQKDEVFQFADATGDSLKLAQYSAENKDAEAIVFCGVHFMAETADILTAENQTVYLPDMRAGCSMADMADIFQTERAWQELIDLLGETIIPLTYVNSTAAIKAFVGRHHGATVTSSNAEKMVKWALERNKRLLFLPDQHLGRNTAFNLGIKLEEMAVWDPILHRLETRVEIDKIKVILWKGHCSVHENFTVENILQTREQYPEMNIIVHPECRREVVALSDYAGSTNYIIDRIKESKAGSSWAIGTEMNLVKRIIHQYPDKHIVSLNPHMCPCLTMNRIDLPHLVWCLDQIDKGENHHVIKVDAEIAKDAKLALQRMLDLA
>NC_021171.1|WP_144061477.1|2772082_2772367_-|hypothetical-protein
MDLLLRDLLRDLFRFLLRLELLRRELLRRELLRRELLRRELLRRELLHLELLRRELLRLELLRRELLRRELLRRELLRRELLRREDRRLVRFIV
>NC_021171.1|WP_015594314.1|2772521_2772950_-|cell-wall-hydrolase
MAVVKANQSDINLMARLLRAEGEGEGVLGMLLVGNVGINRIRANCSDFKGLRTIPQMVYQPHAFEATIHGYFYQRPREKEKRLARRVINGERFWPAKFSLWYFRPGGSCPAQWYSQPFVARYKLHCFYEPKAETCENVYNTF
>NC_021171.1|WP_015594316.1|2773197_2773638_-|peptidylprolyl-isomerase
MAKKGYILMQNGEKIEFDLFPNEAPGTVANFEKLANDGFYNGVTFHRVIPGFVSQGGDPSGTGAGGPGYTIKCETVGNPHKHEAGSLSMAHAGKDTGGSQFFIVHEPQPHLNGVHTVFGKVTSGLEAAKAMKNGDVMEKVEVFDAE
>NC_021171.1|WP_041581090.1|2773708_2774215_-|mismatch-specific-DNA-glycosylase
MKPIPDYLKEGLTILFVGFNPSIRSSELGHHYANPNNRFWTILYKAGITPRKFSSSEDGQLLDYGFGFTNIVNRPTKTAQEITREEYKTGREDLKQKISYFKPEIVCFVGKGVYQEYNSKKAIPWGLQTESVVEGTLDFVAPSSSGLVRMKIEDIINIYAELPKIMKK
>NC_021171.1|WP_015594318.1|2774657_2775770_+|radical-SAM/CxCxxxxC-motif-protein-YfkAB
MLKPITPMYDPWEAYLDMKEYGKLTLTNVEFTTTNLCNMRCEHCAVGYTLQTKDPQALPIDVILKSLEEIPTLRALSITGGEPMLSLSSVKNYVLPLLKYAHERGIRTQINSNLTVDLQRYELIAPYLDVLHISHNWGTEEDFANAGFARMESKPSYSQRLKSFERMIENSRALVKSGVMVSAETMLNKRTFPYLEKIHRQIVDEMLCQRHEIHPMYPSDFASNLAFLSINEIRQGIHHLLDIRNQDVWMLFGTLPFYPCNTNEEDLSLLKRLYESPNVTVRNDPDGRSRLNINIFSGDIIVTDFGDIPPLGNIKETGLQHAYENWLTTSMAKQLTCHCPCVECLGPNILVKDRYYPEVDFTKNNAKISK
>NC_021171.1|WP_187292104.1|2776021_2777863_-|SEC-C-domain-containing-protein
MSINRNDACPCGSGKKYKKCCLKQKNVVQINEVKEERFFQQKHELVLKIRSFIESKLSFNRYAQLQAEFSQRSEHTVPPDFEDGFFQFWLFFCHRYESGLRGIEWFFQSQEARLSPDEKTMAKRWTGLSLKLVEAVQKGDDYVVFEDVLTKDKFTVNDTSENIPEFLPWYSTIGLLEEFGDKYYFNGVRIFKGPTNLYQAVNRVQNLVETEKLSNEQILFDFYPEILSSFLTEQIGLVKEESKNREIPEYILEYEVLNESLLESFLLVERGFILDKDEAGKKIISWVGNWKQYRDNELEGEVLLAEVFGVISIEKDKLIFTSFDQQKTEELKSILKNVSLIVQFVSEKIKTITLPFNAIIKNSFAQMSKEVPPYFALYAQADLLSEIDITIPKYNHKSIRQLVESNQVVWADTWLKQNEYNLYQQVKQQFKKVEVTADFNTVRKLLKLPLSAFVKGGAERHTSVEQIGNPYSQNVIDKEDIPFYEDLGFTPSSIDNFYAKDLVAFFKEKTFGKGEGTVRKYRSSVYLIKEQFESQSLESWNECDESFWTKMIVEDLLEIEVVSNSFRKDFFSTIKALTKWIDSNKNMSISKSALKVINDTEDWLASGKLFQKA
>NC_021171.1|WP_144061587.1|2778075_2778936_+|thermonuclease-family-protein
MPFGTIILVVGITAGCSVPEETVQKEKQKPVEQALPQKLPDNNQATKNETTQVETPVQGQTAKVISVTDGDTIKVQLANGLTEKVRLILVDTPETKHPRLGVQPFGKEASNFTSKELTGKDVTLELDVGQRDQYGRLLAYVWFGNTLFNERLLEEGLARVAVFPPNTKYVDRFREVQKKAQASGIGIWSIENYAQEDGYHSEGTVETPPASNSNSNSNSNSGGSYTNDPSDDQETNLSCAGKIKGNANSKIYHVPGGSYYESTQDNIVWFCTEAEAQAAGYRKSKR
>NC_021171.1|WP_015594321.1|2778993_2780244_-|ArgE/DapE-family-deacylase
MTDEFEKQKLLRFIESRRVDLVRFLQELVAIPSDNPPGDCGVIAEHVHQRLQAYDFKQVSMHEISPEESAKIGMTRVSNVVAYEVFDVEQGPEITLNSHGDVVPPGAGWTKGPYGGEIIDGKLYGRGAAVSKSDIVTFIFAVLALREVATSLEGKVSLAFTFDEETGGEMGPKWLLEKDLIKPDYAVCPGFSYSIVNAHNGCLHMEVTIKGKQAHAAEPQHGHDALESMTGVLAVLYQYRKTLASKKSNVPGITSPTLVVGKISGGINTNVVPDECKIRLDRRLIPEENPEEVEKEIISIITKAAAKVDGIEIEIKRILLAKSFGPISEDSSFVQSFKRNWQQIMEGELLIHGSPLYTDARHFYEAGIPVLLFGAGPRTLLEANGHRADEHVNIADLVNATKIVALSLFDLLKRNN
>NC_021171.1|WP_015594322.1|2780275_2781568_-|M20-family-metallo-hydrolase
MVDVYFIVSKTIHFKKGGYCVKEINVQRIISRIEQLAKCSETSLGVTRLSFTEQSEQADQLVTGWMQAAGMVVRKDAMNNLIGRFEGRKKDASVLLIGSHIDSVLNGGKYDGTLGVITAIEVIGLLNENDEIPEHPIEVISFCDEEGARFHTTFLGSRAMAGTFPREDLERKDDNGISLAGAMRNQYLIPESFPLAKRNEESLFGYLELHIEQGPVLEQVNQPCGVVIGIAGVSRYSFTIKGLAGHAGTVPMQNRCDALSGTAEVLMKIEEMAKLYDPIVATVGKLVVKPGASNVIPETVTGTLDIRGTNQTNKTEFIHGLFEIINEICKRRRLSCQFENIMEVSPVACSDIFINIIEETLLENGVSPKRMISGAGHDAMAIAPITNIGMIFVRCEKGLSHCPEEYVSGDDIRVSAKVLLDTVKQIANIR
>NC_021171.1|WP_144061479.1|2781524_2782859_-|allantoinase
MNDVNEYDLVIKNGSIVSESGIVKADLAILQGKIVEVSTGIPETKGKQQYDAMDLHILPGLIDTHVHLNEPGRAEWEGISSGSRSLAAGGVTTYFDMPLNSSPPTINRENYMKKKQLANQLSLVNFQIWGGLVPENLDQMEELKDCGVIGFKAFMSGSGIDDFHSSDELTLYKGMEKISNLNMILAVHAESDHINLPLTQKIIEEGRYTGKDYSESRPVASEIEAVQKVITLAKMTGCKLHIVHASSSRVVGKIQQAKLDGVDISVETCPHYLSLTVDHLDELGAIAKCAPPLRDKQEVELLWKSLQRGEIDMIGSDHSPSPIEMKGGNIFEAWGGISGAQSMLNILLEEGYWKRQIPLETIVRLTSSAPAKRFNLYPTKGSLNVGSDADITIIDLKQAFILKKDDLFYKHPHSPYIGKKFRGKIIATLVNGRCVFHCEQNHPL

Crispr_ID: NC_021171_8

• CRISPR_ID: NC_021171_8
• CRISPR_location: 3332153-3332229
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_021171_8

Consensus_repeat	Method
CCAAAATCCAAGAGTCGCGGAAAAAC	CRISPRCasFinder

spacers of NC_021171_8

>8.1|3332179|25|NC_021171|CRISPRCasFinder
GGGAACCAAAGATTCGCTATGATGA

CRISPR arrays and Neighbor proteins around NC_021171_8

CRISPR arrays

The CRISPR arrays of NC_021171_8

>merge|NC_021171|8|3332153-3332229|CRISPRCasFinder
CCAAAATCCAAGAGTCGCGGAAAAACGGGAACCAAAGATTCGCTATGATGACCAAAATCCAAGAGTCGTGGAAAAAC

>NC_021171|8|6|3332153-3332229|CRISPRCasFinder
CCAAAATCCAAGAGTCGCGGAAAAAC	GGGAACCAAAGATTCGCTATGATGA
CCAAAATCCAAGAGTCGTGGAAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_021171.1|WP_015594860.1|3325156_3326458_-|DNA-polymerase-IV	unknown	unknown	gnl|CDD|179337
NC_021171.1|WP_015594863.1|3329508_3329928_-|methylmalonyl-CoA-epimerase	unknown	unknown	gnl|CDD|213772
NC_021171.1|WP_015594864.1|3330459_3330972_-|L,D-transpeptidase	unknown	unknown	gnl|CDD|341130
NC_021171.1|WP_015594865.1|3331001_3331997_-|aromatic-acid-exporter-family-protein	unknown	unknown	gnl|CDD|226614
NC_021171.1|WP_015594870.1|3338760_3338913_+|YpzG-family-protein	unknown	unknown	gnl|CDD|372924
NC_021171.1|WP_015594857.1|3320805_3321741_-|ribonuclease-Z	unknown	unknown	gnl|CDD|274246
NC_021171.1|WP_041581154.1|3326558_3327680_-|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl|CDD|349932
NC_021171.1|WP_015594868.1|3334388_3336578_-|methylmalonyl-CoA-mutase	unknown	unknown	gnl|CDD|236508
NC_021171.1|WP_015594869.1|3336574_3338431_-|methylmalonyl-CoA-mutase-small-subunit	unknown	unknown	gnl|CDD|239649
NC_021171.1|WP_015594873.1|3341325_3342321_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	unknown	unknown	gnl|CDD|223997
NC_021171.1|WP_015594867.1|3333315_3334389_-|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl|CDD|236515
NC_021171.1|WP_187292111.1|3330084_3330180_+|stressosome-associated-protein-Prli42	unknown	unknown	unknown
NC_021171.1|WP_015594858.1|3322008_3323508_+|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NC_021171.1|WP_015594862.1|3327965_3329516_-|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl|CDD|130187
NC_021171.1|WP_015594871.1|3339019_3340297_-|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl|CDD|237001
NC_021171.1|WP_015594866.1|3332720_3333158_-|BrxA/BrxB-family-bacilliredoxin	unknown	unknown	gnl|CDD|377667
NC_021171.1|WP_015594859.1|3323614_3325027_-|NADP-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl|CDD|236453
NC_021171.1|WP_015594875.1|3343861_3344971_-|butyrate-kinase	unknown	unknown	gnl|CDD|235099
NC_021171.1|WP_015594874.1|3342424_3343846_-|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl|CDD|235660
NC_021171.1|WP_015594872.1|3340329_3341313_-|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl|CDD|223101

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_021171.1|WP_015594860.1|3325156_3326458_-|DNA-polymerase-IV	gnl|CDD|179337	PRK01810, PRK01810, DNA polymerase IV; Validated.	0
NC_021171.1|WP_015594863.1|3329508_3329928_-|methylmalonyl-CoA-epimerase	gnl|CDD|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	3.82996e-60
NC_021171.1|WP_015594864.1|3330459_3330972_-|L,D-transpeptidase	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	9.02935e-34
NC_021171.1|WP_015594865.1|3331001_3331997_-|aromatic-acid-exporter-family-protein	gnl|CDD|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	8.7189e-85
NC_021171.1|WP_015594870.1|3338760_3338913_+|YpzG-family-protein	gnl|CDD|372924	pfam14139, YpzG, YpzG-like protein. The YpzG-like protein family includes the B. subtilis YpzG protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 50 amino acids in length. There is a conserved QVNG sequence motif.	6.73298e-17
NC_021171.1|WP_015594857.1|3320805_3321741_-|ribonuclease-Z	gnl|CDD|274246	TIGR02651, Ribonuclease_Z, ribonuclease Z. Processing of the 3-prime end of tRNA precursors may be the result of endonuclease or exonuclease activity, and differs in different species. Member of this family are ribonuclease Z, a tRNA 3-prime endonuclease that processes tRNAs to prepare for addition of CCA. In species where all tRNA sequences already have the CCA tail, such as E. coli, the need for such an enzyme is unclear. Protein similar to the E. coli enzyme, matched by TIGRFAMs model TIGR02649, are designated ribonuclease BN. [Transcription, RNA processing].	3.17567e-148
NC_021171.1|WP_041581154.1|3326558_3327680_-|M20/M25/M40-family-metallo-hydrolase	gnl|CDD|349932	cd05683, M20_peptT_like, M20 Peptidase T like enzymes specifically cleave tripeptides. Peptidase M20 family, PeptT (tripeptide aminopeptidase; tripeptidase)-like subfamily. This group includes bacterial tripeptidases as well as predicted tripeptidases. Peptidase T acts only on tripeptide substrates, and is thus called a tripeptidase. It catalyzes the release of N-terminal amino acids with hydrophobic side chains from tripeptides with high specificity; dipeptides, tetrapeptides or tripeptides with the N-terminus blocked are not cleaved. Tripeptidases are known to function at the final stage of proteolysis in lactococcal bacteria and release amino acids from tripeptides produced during the digestion of milk proteins such as casein.	0
NC_021171.1|WP_015594868.1|3334388_3336578_-|methylmalonyl-CoA-mutase	gnl|CDD|236508	PRK09426, PRK09426, methylmalonyl-CoA mutase; Reviewed.	0
NC_021171.1|WP_015594869.1|3336574_3338431_-|methylmalonyl-CoA-mutase-small-subunit	gnl|CDD|239649	cd03677, MM_CoA_mutase_beta, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta heterodimers. For P. shermanni MCM, it is known that only the alpha subunit binds coenzyme B12 and substrates. The role of the beta subunit is unclear. MCM catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. The reaction proceeds via radical intermediates beginning with a substrate-induced homolytic cleavage of the Co-C bond of coenzyme B12 to produce cob(II)alamin and the deoxyadenosyl radical. MCM plays an important role in the conversion of propionyl-CoA to succinyl-CoA during the degradation of propionate for the Krebs cycle. Methylobacterium extorquens MCM participates in the glyoxylate regeneration pathway. In M. extorquens, MCM forms a complex with MeaB; MeaB may protect MCM from irreversible inactivation. In some bacteria, MCM is involved in the reverse metabolic reaction, the rearrangement of succinyl-CoA to methylmalonyl-CoA. Examples include P. shermanni MCM during propionic acid fermentation and Streptomyces MCM in polyketide biosynthesis.	4.62223e-163
NC_021171.1|WP_015594873.1|3341325_3342321_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha	gnl|CDD|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	1.85489e-158
NC_021171.1|WP_015594867.1|3333315_3334389_-|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl|CDD|236515	PRK09435, PRK09435, methylmalonyl Co-A mutase-associated GTPase MeaB.	0
NC_021171.1|WP_015594866.1|3332720_3333158_-|BrxA/BrxB-family-bacilliredoxin	gnl|CDD|377667	pfam06491, Disulph_isomer, Disulphide isomerase. This family of proteins has disulphide isomerase activity, EC:5.3.4.1. It has a similar fold to thioredoxin, with an alpha-beta-alpha-beta-alpha-beta-beta-alpha topology. It has a conserved CGC motif in the loop immediately downstream of the first beta strand. This motif is essential for activity.	1.9706e-86
NC_021171.1|WP_015594858.1|3322008_3323508_+|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_021171.1|WP_015594862.1|3327965_3329516_-|acyl-CoA-carboxylase-subunit-beta	gnl|CDD|130187	TIGR01117, methylmalonyl-CoA_decarboxylase_alpha-subunit, methylmalonyl-CoA decarboxylase alpha subunit. This model describes methymalonyl-CoA decarboxylase aplha subunit in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na+ transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across the membrane. [Energy metabolism, ATP-proton motive force interconversion, Energy metabolism, Fermentation, Transport and binding proteins, Cations and iron carrying compounds].	0
NC_021171.1|WP_015594871.1|3339019_3340297_-|2-oxo-acid-dehydrogenase-subunit-E2	gnl|CDD|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	1.7817e-162
NC_021171.1|WP_015594859.1|3323614_3325027_-|NADP-dependent-phosphogluconate-dehydrogenase	gnl|CDD|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NC_021171.1|WP_015594875.1|3343861_3344971_-|butyrate-kinase	gnl|CDD|235099	PRK03011, PRK03011, butyrate kinase; Provisional.	0
NC_021171.1|WP_015594874.1|3342424_3343846_-|dihydrolipoyl-dehydrogenase	gnl|CDD|235660	PRK05976, PRK05976, dihydrolipoamide dehydrogenase; Validated.	0
NC_021171.1|WP_015594872.1|3340329_3341313_-|alpha-ketoacid-dehydrogenase-subunit-beta	gnl|CDD|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0

Protein sequences

>NC_021171.1|WP_015594865.1|3331001_3331997_-|aromatic-acid-exporter-family-protein
MEFKIGYRTIKTAVGTSLSIILAQSLGLHNFVSAGILTILCIQVTRRKSLRASWDRLLACLLAMLFASVFFEIIAYHPLVIGLLLLFFIPTLVMCKAQAGVVSSSVILLHIYSAGKISLDIISNEFGIIIIGIGVALIMNLYMPSVDLKLDVYQEKIEEKFKKIFMEIVHYLRTNESDWDGKEITEVAKLIDEAKILAFRDVENRLLKQENIYYHYFRIREKQFEIIERVLPIVTSIEHMVRQREIIANFMEELAEGINPGNRTYFYLEKLMNMKREFENMEMPKSREEFEARSALLHFTNEMERYLIIKSTFKGLEKNSKANRKRTTETN
>NC_021171.1|WP_015594864.1|3330459_3330972_-|L,D-transpeptidase
MVQFISAFLFTLAFSPLWPLGTNPIVGDPFVIVNKQTNQIALVDENRVQTVVGVATGITNDLTPEGLFTVTVKAINPYYRKKNIYGGDPNNPLGTIWVGFDARGTDGRIYGLHGTNHPESIGRYVSQGCIRLQNEAIESLYEYIPLGTKILILSTKKDFEQLAREYGAMD
>NC_021171.1|WP_187292111.1|3330084_3330180_+|stressosome-associated-protein-Prli42
MGNRKARKVIVMLMLGAMLASTLLLGLSRFL
>NC_021171.1|WP_015594863.1|3329508_3329928_-|methylmalonyl-CoA-epimerase
MVKKVDHIGIAVKSLEQSLSFYTEILRLPLIQIEEVPSQKVKVAFIQVGETNIELLEPTAEDSPIAKFIEKRGEGIHHIALGVGSIQERIMEVKEKGVRMIDNEPKTGAHGAKVAFMHPKSTGGILYEFCEKQGSNEHA
>NC_021171.1|WP_015594862.1|3327965_3329516_-|acyl-CoA-carboxylase-subunit-beta
MPDIYEKIYELYDLKREIELGGGDARIAKQHEKGKLTARERIELLVDPGTFVELNAFIEHRSLDFGLENLKGPGDGVVTGYGKINGRPIYLFSQDFTVFGGALGEMHAMKIANVMDLAAKNGAPFVGLNDSGGARIQEGVVSLDGYGQIFYRNAIYSGVIPQISVILGPCAGGAVYSPAITDFVFMVEKTSQMFITGPKVIETVTAEKISAENLGGAKVHSTISGNCHYHAETEAEVIQAVRDVLSYLPNNCNEMPPRLEPSEDDDYRPELTEVVPINATKPYDVRAVIQQVVDSESFMEIHKDFARNIVVGFARIKGEPVGLVCNQPKFMAGGLDIDSSDKAARFIRLCDSFNVPIITFEDVTGFFPGVKQEHGGIIRHGAKILYAYSEATVPKLTVITRKAYGGAYVALNSKSIGADLVFAWPNAEIAVMGPQGAANIIFAREIANSPDPEATRAAKIEEYREKFANPYVAASRGMVDDVIDPRETRIKLIQALEMLRNKEEKRPKKKHGNIPL
>NC_021171.1|WP_041581154.1|3326558_3327680_-|M20/M25/M40-family-metallo-hydrolase
MINQERLLNEFLELVQIDSETKFETEIAKVLKAKFTQLGVDVFEDDTTSITGHGAGNLICTLKGTKEGVDTIYFTSHMDTVVPGNGVKPSIKDGYVVTDGTTILGADDKTGLAVMLETVRLLKEQNIPHGTIQFIITVGEESGLHGSKALDRNLITAKYGYALDSDGKVGNIIVAAPTQAKITAVIHGKTAHAGVAPEKGISAITIAAKAVARMSLGRIDEETTANIGRFEGGKQTNIVADRVDILAEARSLIPEKMEKQAQKMKEAFESAASEMGGTAEVTIDVMYPGFKFGAGDHVVEVARKAAEKIGRNCELLHSGGGSDANVIAGFGIPTVNLAVGYEEIHTTNERMSVEELYKLAEMTIAIIEEVSAS
>NC_021171.1|WP_015594860.1|3325156_3326458_-|DNA-polymerase-IV
MKEMYPKNGRVILHVDMNSFYASVEMAHDPSLKGKPLAIAGNVEERRGIIVTCSYEARKFGVKTTMPLWQAKKLCPQIIVRKPNFDRYRAASTSMFDILRRYSQLVEPVSIDEGYMDITDSYELGSPLQIAESIQEVLLKELDIPCSIGIAPNKFLAKMASDMKKPLGITILRKRDISSVLWPMEAGEMHGVGKKTAEKLAPLGILTIGDLAKANDIQLKALLGINGLRLKDRANGVDKRTVNPESVYDFKSIGNSTTLAKDVSNQHLLFQVIEGLVEKVTQRLKRKKVLAQTISVTIRYKDRKTITRSKKLTNPIGSSEDINAAAKRLFLKHWNGEPIRLLGVTGTDLLEQDDAIKQLDLFSFEQEAKKEPLYHTMEMLREKYGKHIIEKAGDLADHQKSTPTIGTDTSFNKDFLQTSSRSWKKNHDKKEIE
>NC_021171.1|WP_015594859.1|3323614_3325027_-|NADP-dependent-phosphogluconate-dehydrogenase
MSKQQIGVIGLAVMGKNLAMNIESRGYTVSVYNRSREKTDEMLAEVAGKNIVGTYSPEEFVQSLEKPRKILLMVKAGAATDATIEQLKPLLDKGDIVIDGGNTFFVDTQRRNKELSALGIHFIGTGVSGGEEGALRGPSIMPGGQKEAHELVAPIFEAISAKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLISEAYFLLKNTLGLSASEFHSVFAEWNKGELDSYLIEITADIFTKVDEETGKPLVDLILDTAGQKGTGKWTSQSALDLGVPLPIITESVFARFISAMKDERIAASKLLKGPKTNGFTGDKQAFIEAVRKALYMSKICSYAQGFAQMRSASEEYNWDLRYGDISMIFRGGCIIRAQFLQKIKDAYDLDPGLKNLLLDPYFNEIVGSYQDALREIIGVAVQNGIPVPCFSAALSYYDSYRMETLPANLLQAQRDYFGAHTYQRIDKEGIFHTEWMDK
>NC_021171.1|WP_015594858.1|3322008_3323508_+|glucose-6-phosphate-dehydrogenase
MKQNEKPTALIMIFGATGDLANRKLFPSLYQLYEKGNLDRFAVIGVARRSLSHEQFKQNVKDSILSSGNSSENIDEFISHFFYHSHDVTNSSSYTALNQLAGRLDSSFQLDGNRIFYLAMAPEFFGTIAEHLKLDGLTNVDGFKRLVIEKPFGHDLASAKKLNQQIRTAFSENEIYRIDHYLGKEMVQNIEVIRFANAMFEPLWNNRYISNIQITSSEVLGVEERGRYYEKSGALRDMVQNHMLQMVALLAMEPPIRLTTDEIRSEKVRVLRALRQVQGLDVDKYFVRGQYGEGKINEDQLPAYRNEEMVDPNSNTETFVAGKLMIDNFRWAGVPFYIRTGKRMLTKQTKIVVQFKDIPMNLYYQTEKMLNPNLLVIHIQPEEGITLHFNAKKSGQSLDATPVKLSFANKGINGMNTPEAYELLLYDCMRGDATNFTHWDEVALSWSFVDNISNVWEKTKETRYPNYESGTMGPQGAINLLEKDGFHWWPVTNLDVETC
>NC_021171.1|WP_015594857.1|3320805_3321741_-|ribonuclease-Z
MDVFFLGTGAGIPAKLRNVTSIALKLLEERGSIWLFDCGEATQHQILHTSIKPRRIEKIFITHLHGDHIYGLPGLLSSRSFQGGETEVIIYGPKGLKEYITVSLSVSQTYLKYPLKVIEIDEGIIFEDEQFIVETHVLEHGIPSYGYRIIEKDRPGTLLADKLAEAGIKPGPIYKKIKNGENVTTEDGMFIKACEFLGQTLKGRIVTILGDTRQCDHAAKLATDADLLVHEATFSKGEKSLAYDYFHSTTHQAAKIAKRAGVKKLCLTHISSRYDREAWNELVAEAKEIFPNTEIAEDFKEITVPVDKNMD
>NC_021171.1|WP_015594866.1|3332720_3333158_-|BrxA/BrxB-family-bacilliredoxin
MNIDFNFFMNDTVRQARQEIVAAGYEELTTPTAVDEALSKKGTTLVMINSVCGCAGGVARPAAAHALHYDKRPDHLVTVFAGQDKEATEKARSYFTGFPPSSPSFALLKDGKILTMVERHDIEGYDPMTVVQKIQNTFEQYCEEV
>NC_021171.1|WP_015594867.1|3333315_3334389_-|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MGVNKNTDRDEPGNLNRMSNSPQKRFRKRSDVFEPSVEELATGVRSGDRSMLARAITLIESNAEHHFQKGQQLLQSLLPYSGNSIRIGITGVPGAGKSTLIEAFGTYLCEQGHKVAVLAVDPSSSISGGSILGDKTRMGELANNPRAFIRPSPSQGKLGGVHRKTRETLALCEASGFDVILIETVGVGQSEVVVRNMVDFFMLIVLTGAGDELQGMKKGIMELADAIVVNKADGANKPLAEKTRLEYMRIVHFLLPATKGWATKVATCSALNDEGINGIWDIICDFDRQTKESGVFDSRRRIQTKEWIYAMIIDQLQSSFFHHPEVKFLLPKVENEVISGDRTVTSAVESLFKVYLG
>NC_021171.1|WP_015594868.1|3334388_3336578_-|methylmalonyl-CoA-mutase
MKKPDFKSIEILQDQEVSKKEWQVKAEAEVSKSLDDLLFETNEYIKLKPLYSKDDLDGMTHLDDKPGIAPFTRGPYPTMYVNRPWTVRQYAGFSTAEESNAFYRRNLAMGQKGLSVAFDLATHRGYDSDHPRVEGDVGKAGVAIDSILDMKTLFDGIPLDQMSVSMTMNGAVLPIMAFYIVTAEEQGVSQEKLSGTIQNDILKEYMVRNTYIYPPEMSMKIIADIFEYTSKYMPKFNSISISGYHMQEAGAPADIELAYTLADGLEYVRTGLKAGIPIDKFAPRLSFFWAIGMNYFMEVAKMRAARTIWAKMIQTFEPKNAKSLALRTHSQTSGWSLTEQDPFNNVTRTLIEAHAATMGHTQSLHTNALDEAIALPTDFSARIARNTQLFLQEEAGVTNVIDPWGGSYYVEALTEQLVKRAWEHIEEIENLGGMAKAIETGLPKMKIEEAAARKQAQIDSGKEIIIGVNQHRLEKEEDIDILEVDNTAVRLKQLEKLDLLKSTRDEEAVQEALAAITRAAETGEGNLLELAVNAARLRASLGEISTAIEVVASRHKAIIRSISGVYSTAFSNEEEISIVKRMTDEFLENEGRRPRILVAKLGQDGHDRGAKVIATAFSDLGYDVDMGPLFQTPEETARQAVENDVHVVGFSSLAAGHKTLLPQLVNELKKLGREDILVVIGGVIPAQDYDYLYEHGAAAIFGPGTVIPIAAQKVIETIYQRLGYEEVVK
>NC_021171.1|WP_015594869.1|3336574_3338431_-|methylmalonyl-CoA-mutase-small-subunit
MSISKMINEVFPAATAEQWKQKAEETLKGKPVETLGKSTYEDIRLKPLYSKEDLENQIVSQFPGYQDYRRGINPLGYVTSDWKVAQTITATNPDELKELLLSSFQKGQTAISFEVSEKLISEISSILADIVTSYPFNVNAKEFQAELLKAVQSLAEKSDGRQELSGYIGMDPIAIAVESGSEVEGVYEQWANTIRDTTESFPNLKTILVDTTPYHNGGANAVQELAIALATGVEHISKLTEQGLSLETVLDKMVFKFAIGSNFFMEMAKLRAARLLWSKLTESYGATPELRKMVISAETSKFTKTKYDPYVNLLRAGNEAFSAILGGIQYLHVSPFNEPEGQATAFSDRIARNTQLIIKEEAHLKKVVDPAGGSWYIESLTNEVAQKAWDLFLEIDAKGGIISTLRSNWLQEQIAAVKEKRQKDIFTRKQSIIGTNIYANLQDQPLQVAETKMSSNAEFAIKPIAQERLAQGYEELRSRAEQLTEQTGKGPAVGLIALGALKQHKARADFITGFVAPGGIQTVKSEEINSFEDAVAFVENTPLKHYCICGGNDQYNEIVLELVTKLNKQYPNVQLYLAGIPENQSDFSDAGVTDCITLKSNCYETLSKLLDEMEVESK
>NC_021171.1|WP_015594870.1|3338760_3338913_+|YpzG-family-protein
MSYKDHLDPHSELFHHNWTRRKRSKSQVNGETKDTQTTIILRSNAKAHHW
>NC_021171.1|WP_015594871.1|3339019_3340297_-|2-oxo-acid-dehydrogenase-subunit-E2
MALKQIKMPQLGESVTEGTISKWLVSIGDQVNKYDPLAEVMTDKVNAEIPSSFAGVIKELSAAEGDTLSVGEIICLIDVNDSEVMSKVGQTTAYQALGGAPTNNQGNKTRYSPAVLKMSQEHGIDLTQVQGTGAEGRISRKDLLRLIDSGMIPKAGEPTPFSGARQEQALPRQELETTQKQTVTVPSISVAAGDLEIPVTGVRKAIAANMLRSKHEAPHAWTMIEVDVTTLVELRNSLKDEFKQKESFNLTFFAFFVKAVAQSLKEVPQINSMWAGDKIIQKKDINVSIAVATDTALFVPVIKNADEKTIKGIAREISEYANKARSGKLTSEEMQGGTFTVNNTGSFGSVQSMGIINYPQAAILQVETIIKRPVVLNNNMIAIRDVVNLCMSLDHRVLDGRICGRFLQRVKEILENTNKENTLIY
>NC_021171.1|WP_015594872.1|3340329_3341313_-|alpha-ketoacid-dehydrogenase-subunit-beta
MAVISYIDAVTMAIQEEMERDSKVFVLGEDVGKKGGVFKATQGLYEKFGEERVIDTPLAESAIAGVGIGAAMYGMRPVAEMQFADFIMPAVNQIISEAAKIRYRSNNDWSCPLVIRAPYGGGIHGALYHSQSVEAVFANQPGLKIVMPSTPYDVKGLLKAAIRDNDPVLFFEHKRAYRLIKGEVPETDYTLPIGKADVKRKGDDITVITYGLCVHFALQAAERLASEGISAHILDLRTVYPLDQEAIIEAASKTGKVLLVTEDNKEGSIISEVAAIIAENCLFELDAPIKRLAGPDIPAMPYAPTMEKYFMVNPDKVEIAMRELAEY
>NC_021171.1|WP_015594873.1|3341325_3342321_-|thiamine-pyrophosphate-dependent-dehydrogenase-E1-component-subunit-alpha
MGENRHQALGLSDEKVLEMYETMLLARRIDERMWLLNRAGKIPFVISCQGQEAAQVGAAFALDKEQDYILPYYRDLGVVLTFGMTTKEIMLSGFAKAEDPNSGGRQMPGHFGQKKNRIVTGSSPVTTQVPHAVGIALAGKMEKKNLVTFVTFGEGSSNQGDFHEGANFAAVHKLPVIFMCENNKYAISVPISKQMACEKVSDRAIGYGMPGFTVNGNDPLEVYQVVKDACDRARRGDGPTLVETVSYRLTPHSSDDDDRSYRAQDEVAEAKTNDPILTFGAYLKEVGILDDQLEKQINDRFLKMINEATDYAELAPYAEPEEALKFVYGIE
>NC_021171.1|WP_015594874.1|3342424_3343846_-|dihydrolipoyl-dehydrogenase
MAQEYDLVILGGGTGGYVAAIRASQLGLKTAIVEKAKLGGTCLHSGCIPSKALLRSAEVFATMKRSADFGVFANDITFDFSKVQERKNNIVAGLHKGVQHLMKQGKIDVYEGLGRILGPSIFSPMPGTISVEMNNGQENEMLIPKNVLIATGSRPRLLPGLEVDGTFVLSSDEALAMVTLPKTILIVGGGVIGIEWASMLSDFGVLVTVIEFADQIIPTEDKEISKEMQRLMKKKGIKIVTGAKVLSESLQKDNGVSVSAEVKGEIRQFSAEKLLVSVGRLANVEGIGIENTEIQIDKGYIATNQFFQTKESHIYAIGDVIGGLQLAHVASAEGVIAVEHIAGLTPTPLAYNLVPKCIYSKPEVASVGLTEDEANSKGHQIKIGKFSFRAIGKALVFGESDGFVKIIAEQDTNDILGVHMIGPHVTDLISEAGLAMVLDATPWEVSKAIHPHPTLSEAISEAALAVDGKAIHS
>NC_021171.1|WP_015594875.1|3343861_3344971_-|butyrate-kinase
MTPEYRILVINPGSTLTKIGIFDNEIPLFEKAIRHDVDMIQSCLGISEQYEFRKQTILETLEYEGINISKIHAVCGRGGLLRPITGGTYAVNSLMLEDLKTGFAGQHASNLGGILAFEIASGLNIPSFIVDPVVVDELEPIARISGLPLVERKSIFHALNQKAVARRIAKQFNKKYEDLNFIVIHMGGGITVGAHKLGKVIDVNNGLHGEGPFSPERAGTVPVGDLITLCFSGEYDLEVMMKKLVGAGGLVGYLGTNDTLKVERMIKNGNEKAKLIYSAMAYQVAKEIGAASVVLAGKVDAIILTGDLAYGKGFVAEITEKINWIADVIVEPGENELQSLAEGALRILRGEEEAKDYPGELMKSNLHYR

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_021171_7	7.5|2771702|18|NC_021171|CRT	2771702-2771719	18	NC_021171.1	2771378-2771395	0	1.0
NC_021171_7	7.7|2771810|18|NC_021171|CRT	2771810-2771827	18	NC_021171.1	2771978-2771995	1	0.944
NC_021171_8	8.1|3332179|25|NC_021171|CRISPRCasFinder	3332179-3332203	25	NC_021171.1	3190885-3190909	2	0.92

1. spacer 7.5|2771702|18|NC_021171|CRT matches to position: 2771378-2771395, mismatch: 0, identity: 1.0

tcgctctactcgtcgctc	CRISPR spacer
tcgctctactcgtcgctc	Protospacer
******************

2. spacer 7.7|2771810|18|NC_021171|CRT matches to position: 2771978-2771995, mismatch: 1, identity: 0.944

ccggtctactcgtcgctc	CRISPR spacer
ccggtctacccgtcgctc	Protospacer
*********.********

3. spacer 8.1|3332179|25|NC_021171|CRISPRCasFinder matches to position: 3190885-3190909, mismatch: 2, identity: 0.92

gggaaccaaagattcgctatgatga	CRISPR spacer
gggaatcaaagagtcgctatgatga	Protospacer
*****.****** ************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_021171_3	3.1|1743364|28|NC_021171|CRISPRCasFinder	1743364-1743391	28	MN657122	Psychrobacter sp. strain ANT_H56B plasmid pA56BH4, complete sequence	2727-2754	5	0.821
NC_021171_4	4.5|2189422|30|NC_021171|CRT	2189422-2189451	30	MH588544	Caulobacter phage CcrBL10, complete genome	89975-90004	6	0.8
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1213335-1213364	6	0.8
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	994811-994840	6	0.8
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1458514-1458543	6	0.8
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	2055174-2055203	6	0.8
NC_021171_7	7.2|2771462|30|NC_021171|CRT	2771462-2771491	30	NZ_AP014706	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence	379897-379926	6	0.8
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	JX681814	Burkholderia phage phiX216, complete genome	15430-15459	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	CP008753	Burkholderia phage BEK, complete genome	9336-9365	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NC_009236	Burkholderia phage phiE12-2 chromosome, complete genome	27820-27849	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	CP000623	Burkholderia phage phiE202, complete genome	26816-26845	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	DQ087285	Burkholderia pseudomallei phage phi52237, complete genome	28726-28755	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	CP000624	Burkholderia phage phiE12-2, complete genome	27820-27849	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NC_007145	Burkholderia prophage phi52237, complete genome	28726-28755	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NC_009234	Burkholderia phage phiE202 chromosome, complete genome	26816-26845	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NC_019408	Caulobacter phage CcrRogue, complete genome	91045-91074	8	0.733
NC_021171_4	4.7|2189506|30|NC_021171|CRT	2189506-2189535	30	NC_019408	Caulobacter phage CcrRogue, complete genome	91240-91269	8	0.733
NC_021171_4	4.5|2189422|30|NC_021171|CRT	2189422-2189451	30	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	1204878-1204907	9	0.7

1. spacer 3.1|1743364|28|NC_021171|CRISPRCasFinder matches to MN657122 (Psychrobacter sp. strain ANT_H56B plasmid pA56BH4, complete sequence) position: , mismatch: 5, identity: 0.821

taagaataaacgctattttgagaatatg	CRISPR spacer
ttatcataagcgctattatgagaatatg	Protospacer
* *  ****.******* **********

2. spacer 4.5|2189422|30|NC_021171|CRT matches to MH588544 (Caulobacter phage CcrBL10, complete genome) position: , mismatch: 6, identity: 0.8

----gagccgtcgttcaaaccgccgttcgagccg	CRISPR spacer
tgaagag----cgttcgacccgccgttcgagccg	Protospacer
    ***    *****.* ***************

3. spacer 4.7|2189506|30|NC_021171|CRT matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcactgtcgttccagccgtcgtgcaggccg	Protospacer
. .*.******* ********* *******

4. spacer 4.7|2189506|30|NC_021171|CRT matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcactgtcgttccagccgtcgtgcaggccg	Protospacer
. .*.******* ********* *******

5. spacer 4.7|2189506|30|NC_021171|CRT matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcactgtcgttccagccgtcgtgcaggccg	Protospacer
. .*.******* ********* *******

6. spacer 4.7|2189506|30|NC_021171|CRT matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.8

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcactgtcgttccagccgtcgtgcaggccg	Protospacer
. .*.******* ********* *******

7. spacer 7.2|2771462|30|NC_021171|CRT matches to NZ_AP014706 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_2p, complete sequence) position: , mismatch: 6, identity: 0.8

ccgatctactcgtcggtctactcaccgatc	CRISPR spacer
acgatctactcttcggcctactcaccctgc	Protospacer
 ********** ****.*********   *

8. spacer 4.7|2189506|30|NC_021171|CRT matches to JX681814 (Burkholderia phage phiX216, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

9. spacer 4.7|2189506|30|NC_021171|CRT matches to CP008753 (Burkholderia phage BEK, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

10. spacer 4.7|2189506|30|NC_021171|CRT matches to NC_009236 (Burkholderia phage phiE12-2 chromosome, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

11. spacer 4.7|2189506|30|NC_021171|CRT matches to CP000623 (Burkholderia phage phiE202, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

12. spacer 4.7|2189506|30|NC_021171|CRT matches to DQ087285 (Burkholderia pseudomallei phage phi52237, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

13. spacer 4.7|2189506|30|NC_021171|CRT matches to CP000624 (Burkholderia phage phiE12-2, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

14. spacer 4.7|2189506|30|NC_021171|CRT matches to NC_007145 (Burkholderia prophage phi52237, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

15. spacer 4.7|2189506|30|NC_021171|CRT matches to NC_009234 (Burkholderia phage phiE202 chromosome, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
gcatcgttgttcgtgccgtcgttcaggcaa	Protospacer
. ..***.***** ************** .

16. spacer 4.7|2189506|30|NC_021171|CRT matches to NC_019408 (Caulobacter phage CcrRogue, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
tgaagagcgttcgagccgtcgttcgagccg	Protospacer
 *.  . *****************..****

17. spacer 4.7|2189506|30|NC_021171|CRT matches to NC_019408 (Caulobacter phage CcrRogue, complete genome) position: , mismatch: 8, identity: 0.733

aggccgtcgttcgagccgtcgttcaggccg	CRISPR spacer
cgaagagcgttcgagccgtcgttcgagccg	Protospacer
 *.  . *****************..****

18. spacer 4.5|2189422|30|NC_021171|CRT matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

gagccgtcgttcaaaccgccgttcgagccg	CRISPR spacer
ggcggttcgttcaaacagccgttcgagaaa	Protospacer
*.    ********** **********  .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	221385 : 272511	67	Bacillus_phage(26.67%)	tRNA,protease,portal,integrase,capsid,terminase	attL 225635:225653|attR 268672:268690
DBSCAN-SWA_2	346610 : 356572	9	Synechococcus_phage(50.0%)	NA	NA
DBSCAN-SWA_3	3583108 : 3644239	59	uncultured_Mediterranean_phage(14.29%)	transposase,protease,coat,tRNA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_021171|221385:272511|DBSCAN-SWA
TATGAGTGAATTTGAGTTCATTTCAAATAATCCGCAACAAACAACAGAATTTGCTAAACAACTAGCTCAAAAACTTCAACCTGGAGATGTGATTGCTCTTGAGGGTGATTTAGGTGCGGGGAAGACCACTTTTACAAAAGGGCTTGCAGAGGGGTTAGGTATCAGTAGAACGGTCAATAGCCCAACTTTTACGATCATAAAAGAATATCAAGGGAGAATTCCGCTTTATCATATGGATGTATATAGAGTAGAGGATTCTTTTGAAGATCTAGGTTTTGATGAGTATTTCGAAGGAAATGGTGTAACTGTTGTGGAGTGGGCTCATCTCATTAAGGATCAGTTACCTGATAGTATATTGACGATTTACCTATACCATGAAAATGAATATGCACGTAAAATTGTTTTAAAACCGCGAGGGACTCGCTATGAGGAATTATGTAAGGAGATTAACTAATGAAGGTATTAGCAATTGATACTTCTAATTATGCTTTAGGAATTTCACTCATTGATGAAGATAAGGTTATTGGTGAATACATTACGAATGTAAAGAAAAATCATTCTGTCCGAGTCATGCCAGCAATTGAGGAGTTGATGAAGGTTTGTGATATCCTTCCTTCAGATTTAACCAAGATAGTTGTTGCAAAAGGGCCAGGCTCATATACGGGTGTGCGAATCGGTGTAACGATTGCCAAAACACTGGCTTGGACATTGAATATTCCGCTAGTAGGGGTTTCCAGCTTAGAAGTATTGGCTGCATCAGTCGGTCGTTATTTCCAAGGAAGCATTTCGCCATTATTTGATGCTAGACGAGGACAAGTTTATACCGGGCTTTACCAATTCAATGAAGGAAAACTGCAAGTTATCAAAAAAGACCAGCTTGTACTTTCACAGGACTGGGCGCAGGACTTGAAAAAACGATCTGAAAGCATCTTATTTATTGGTAATGATTTACCGATTCATCGGAATGGGATTGAAGAAGTTCTTACACATCAAGCATACTTTGCAGAGATAACAGAACATAACCCACGTCCTTCCGAGTTGGCTTTGTTAGGAAGGGATTTACCCGGGGAGGATGTTCATTCCTTTGTACCGAATTACATAAGACTTGCTGAGGCAGAGGCAAAATGGTTGGAAGCAAAAAAAGAAATGCAATAGTTTAAAGAAGGAAGAATGATATGAACGGATCACTAACTTTCCGAGATATGGAATTAAAAGATATCGATGATGTACTAAAAATAGAGCATGAATCGTTTACTGCCCCTTGGAGTCGTGAGGCATTTGTCAATGAACTGACAAGCAATCGGTTCGCAGTCTATATTGTCATTGAAGAGGCCGAACAGGTAGTTGGATATTGTGGTGTATGGGTGATTGTGGATGAAGCTCATATAACAAATATTGCACTACTTCCAGAACATAGGGGGAAAAAGCTAGGGGAAGCATTGTTATTGAAGGTAATGGAGGTAACGAAGAAATTGGGTGCAGTAAAGATGACACTTGAAGTGAGGGTAACTAATTCAGTAGCTCTGGCTTTATACCGTAAGCTAGGGTTTAAAGATGGTGCAATTCGTAAAGGGTATTATACTGATAACCGTGAAGATGCTTTAGTAATGTGGGTGGAGTTATGAGAAAAGATCTATTAATAATGGGCATTGAGTCAAGTTGTGATGAAACGGCAGTTGCTATTGTAAAAAACGGACGGGAAATCGTTTCGAATGTTATTGCTTCACAAATTGAAAGTCATAAACGGTTTGGTGGTGTTGTTCCAGAAATAGCATCGCGACACCATGTTGAGCAGATTACAATTGTTTTAGAGGAAGCAATGAAACAAGCAGGAGTCACCTTTAAAGACTTAGATGCCATTGCAGTTACCGAAGGCCCAGGGTTAGTTGGTGCTCTTTTAATTGGGGTAAATGCAGCTAAAGCAATCGCTTTTGCTCATAGTATTCCACTCGTCGGTGTCCATCATATCACCGGTCATATTTATGCGAATCGTCTTGTGACTGAAATGAATTTCCCACTCCTTTCCTTAGTTGTTTCTGGTGGTCATACTGAGCTAGTCTATATGAAGGAACATGGAGATTTTAAGGTTATTGGTGAAACAAGAGATGATGCAGCAGGTGAAGCATATGATAAGGTTGCCCGAACGCTGAATCAACCTTATCCGGGTGGTCCTCATATTGACCGAATGGCACAAGAAGGAAAGCCTACGATCAACTTGCCAAGAGCATGGCTAGAAGAAGGCTCATATGATTTTAGTTTTAGTGGATTAAAATCAGCTGTAATAAATACAGTTCATAATGCAGAGCAACGTGGAGAGAGCATCAAACCAGAGGATCTTGCAGCAAGCTTTCAGCAAAGTGTTATTGATGTGTTAGTTACAAAAGCCGTAAAAGCTGCGAAAGAATATCAAGTTAAGCAGGTCCTACTCGCAGGTGGTGTAGCAGCCAATAAGGGATTAAGAGCGGCACTAACAGAGGCATTTACTAAAATTCCCGAAATCGAGTTGGTCATTCCACCATTATCCTTATGTACGGATAATGCCGCGATGATTGCAGCAGTCGGTAGCGTTTTATTTGAAAAAGGAAAGCGTGCTAACCTTTCATTAAATGGCAATCCTGGATTGGACATCACGATCTACAATTAAATCGAAAATCTCTGTTCTTTCGACAACATTTAATTGAAAACAGATCCTTCTATCCACAATTAATCCGAAAAAACATTTTACTCTTCTTACGCCAAGAAGAGTTTTTTTGTGGATAAGTGTATATAACATGTGTATAGTGTGGATAAGTATAGCGGAAATTGTGGATAATGTGGAAAACCCCTGTGGATGCTGTAAAAATAATAAGCTTAATGTGAATAAAATTGTTAATAAGTAATGAATAACTTTTTCAGTTATGATTTCCCACATATTTTCACGAATTTGGATGAAAAATATCGAAAAAAGTAGATAAATCTCGAAAAAACAACTTGAAAAAAACCACAAAAGTTATGACAAAAGTCGTCAGTTTTGTGGTTTTTTTATTTGCTGTGTAAAATTAGAATGTTGATTTCCGCTACAATCAACAATGAGTTTTAACACAGCCTTTTTATTATAAAATAAGGCTGTTTTCGTAAAATTTGTTGCTATTTACTTATGAGAGTAGAGGCTGATTTCCGCTCCAGGTGCTCGCTTTCCGCGGGGCGTGCGGTGAGCCTCCTCGGCGTTTTACGGAGGCTGCTGAAAAAGTCCTTTTCTATTTAAAATGAAGTTTTTGACAATACACAATCCCAAAATCCCGCCATTTTCCTCTATCGAAGTGGAGGATTCAGTCCGATTTACTCCTCATTATTAAATCGAAAGTGGGGATGGATTTTTCAGGGAATTGCTTTTCTCAAAATTTCTCAGCCTTTTTCAGTGGCCTCGTTTTACGCCTGCGGGGTCTCACCTGTCCCGCTGCTCCCGCAGGAGTCGAGCACCTTCCGCTCCAATCAGTTTCATTTTTAAAGGTATACATTCAATCTTTTAGAAAACAGCATAAAATAATTACCGTTTCAAGATTTCCCTAGTCCTCAGCAAGTTCAGCCCATTCCTCCATCAGTTCTTCAAGCGTGGAATGTGCCGCCTCGTTTTGGCCGTTAAGCTCCAACACTTTTTCATGGTTTTGGTATATCTCTGGGTCACATAATAGCTGTTCGTTAGTTGAGATCAGTGTCTCTAATTTTTCGACACTCGCCTCAATTTCCTCCATTCTTCTCTGTCGTTGGCGCTCCAATTTTTTTGTTTCCTTATCCTGTTGATAAGTATTTTTTACTGGAGTGCCAGCAAGTGTTGTCCCCACCTTAGGTGTATTCTCAAGTGCTTTTAGCTCAACTTGTTCGAGTTTCTTTTCAACGTAGTAGTCATAATCACCTAAATATTCGACAGCGCCGTTCTTCCCTAATTCGATCACTTTTGTAACGATTCGATTAATGAAATAACGGTCATGTGAAACGAATAAAATAGTTCCAGGATAATCGATGAGGGCGTTTTCTAGTACCTCTTTGCTGTCTAAATCCAGATGGTTCGTGGGCTCATCAAGAATGAGGAGATTAGCTTTTTCCATCATAAGCTTGGCGAGGGCAAGTCGAGCTTTTTCTCCGCCGCTTAAGGTTGAAACAATTTTCAAAACATCGTCACCCGAAAATAAAAAATTACCTAAAACAGTTCGAACTTCTTTTTCAGGCTTTAACGGATATTCATCCCATAGTTCATTTAACACACGTTTATTTGATGTTAATTCAGCTTGTTCCTGATCATAATAGCCAATCGAGACGTTGGAGCCTAATTGGAATGTGCCAGCTAACGGATCTAGTTTTTGTACAATAGTTTTTAATAAGGTGGATTTACCGATCCCATTCGGCCCAACCAGCGCGATACTTTCCCCACGGGTAATTCGAATGGATATATTTTCAGATACCCTTTCTTCACCATAACCAACAGCGACAGAATGGACGTTTAACACTTCATTTCCGCTTTGTTTTTCAATATCAAAAGAGAATGTAGCTGATTTCTCATTTCCTAGAGGCCGGTTCATAACATCCATTCGATTAAGTTGTTTCCGCCGGCTTTGCGCCCTTTTTGTAGTGGATGCACGGGCGAGGTTTCGAGCAACAAAATCTTGTAACTTCGTAATTTCATCCTGCTGCTTTTCATACATCTTCATTTCACGTTCATAGTTTTCTGCCTTGTGCACGAGATAGGAACTATAATTTCCTGTGAATTTTAGGATTTGTTGCCGTGACATTTCATAAACCTGGTTGACAACTTTGTCTAAAAAGTAGCGATCATGAGAAACAATTAAAATAGCTCCTTCGTAATTTTGTAAATACTGTTCTAACCAGGACAATGTTTCAATGTCTAAATGGTTGGTGGGTTCGTCCAAAATAAGAATATCGGGTTTGGTTAATAATAATTTTCCAAGTGCAAGCCGCGTTTTTTGGCCACCACTCAGGCTGGAAATTTTGGTAGAATAATCAAAGGTATGAAAATTTAAACCGTGAAGAACGGAACGAATATCGGCCTCGTATTGGTACCCTCCAAGGTCTTTAAATTGAACCTGCAAGAGGTCATAATCCTTTAATAATTTTTCGTAAGTGCTTGTTTCTTTTAATATTGCTGGATCAGACATTTGTTCTTCATATTGTCGAAGCTTTTGTTCAAGAATTCGTAATCCAGCAAAAACCGTAAGCATTTCTTCCCAAATGGAAAGGCTTGATTCCAGCCCTGTATTTTGTGCTAAATACCCAATCGTAACTTCCTTTGGTTTCATGATTTCTCCAGAATCAAAGGACATCTGCCCAGCAATGATTTTTAGCAGAGTAGATTTTCCAGCACCGTTACGGCCGACTAAGGCAATTCTATCTCGAGTTTGTACTTCTAGTTTAATATTAGATAAAATAAGATCTGCACCATAATATTTATTTAATTGGTTTACTTGTAATAATATCATTGTTTTTCACCTCTATTGCGATAGAGTAAGTTTATCGTATTCCTATCATATCAGCAATAACTCCAATCTTGTGAAGGAAAATACAAGTTGATACATACATGTTTGGAAAAATAGTGTATGATTTTGTTAGAAAGGTGTGTACATATGGGAGAATTTACGCATTTTAATGAAGAAGGCCGTGCTAAAATGGTCGATGTTAGCAGTAAACCTGAAACAATTAGAACAGCTCTCGCTTATTCAAGTATTACTGTTAGCTGTGATATTTATGAAAAAATAACCAATAATGAAATGAAAAAAGGGGATGTCCTAGCAGTTGCACAAGTTGCAGCAGTAATGGCATGTAAAAAAACTTGGGATATTATTCCAATGTGTCACCCGATTCCCTTAAATGGTGTAGATATTTCTTTTTCATGGGGAAAAGAAAATAATGACTATATTTTGCACATTTCAGCAAAGGTTAAAACAAAAGGAAATACAGGTGTGGAAATGGAAGCGTTAACAGCAGCCTCGGTTTGTGCTTTAACGGTTTACGATATGTGTAAGGCAGTCGATAAAGGTATGGTAATTGGAAAAACGTTTTTAGTTGAAAAAACAGGTGGGAAAAGCGGAGATTTTCATAGAGAAAACCGTGTGAAATAATTTTATATTGGAGAGGAGAGTTGTTATGGCAAATGAGGGTTCATCCAAAATACCACAGGCCACTGCAAAAAGATTACCACTGTATTATCGTTTCTTAAAAAATTTACATACATCCGGAAAACAGCGCGTTTCATCTGCAGAACTAAGCGAGGCAGTCAAAGTAGATTCTGCGACGATACGCAGAGACTTCTCTTATTTTGGTGCGTTAGGGAAAAAGGGCTACGGTTACAATGTGAATTACCTGTTAACTTTTTTTCGGAAAACGCTTGATCAGGATGAATTGACAAAAGTAGCTTTAATTGGTGTAGGTAATCTAGGCACAGCTTTATTAAATTATAATTTTTTAAAAAATAATAATACGAAGATCGCCATTGCATTTGATGTAGACCCAGCAAAGGTTGGAACAAGTATTCTTGATGTTCCTGTTGCTCATATGGATGATTTAGAGAAAAAAATCAAAGAAGAGAATATTCATGTGGCGATTCTGACGATTCCAGCTCCAGTAGCGCAAGCGACAACTGATCGGTTAACCAGTGGTCCTATTAAAGGAATTCTAAATTTTACGCCAGCACGATTGAATGTTCCTTCGGACATTCGTGTTCATCATATTGATTTGGCCGTAGAATTACAATCACTTGTGTATTTCTTAAAGCACTATCCAAAGGTAGAAGAGGAATAAGGAAAAAATGTACCCATAGAGGGCCGTTGATAAACTAATATGATTTTCAAACCTGTGTAGAATTTATTCTATACAGGTTTTTTATATGGGGAATTTCCAATTTTCCCTTGCATACGAATTCACTATAAAACTTTTGCATTTTGTCATGATATATTCTTTTATTCTTTGTGTTATTTCAATGGGACAATTATACAATGGTATTTGATTAAGTTTTTTCAACACATTTGACCTATTTATTTAAATAATAGGCCCTACCCAAAAAATAACTGTGGATAACTTCCTTTGTTATTTTTATTTATAGATGTGCCGAGGGGATTGGCATGGGTGTCTGTTAAACGATGTTTGTTGATTGTAAGGGAATTTGCGATATTCCAGCGGAAAAAGAAGGGGATGACCCCACGCGAGGCTCGAACGAGGGGGCTTGGCAGTTCGTCCGCGGAAAGGGAGGAGATTCCCTCTTTTTTTGTGTTAACAGCTCTTTTATTTGGAGGTGACCGATATGACAACCAATATGCGCAGAGTTTCATGTGAGCTTGATGAATTCGAACCCCAACTATATATTAATAACAGGAAAAATGAAAAGGTAACTACAGTCATTTTAATAGAGGAAATCCCGTCAGAATTCAAGGATGACATTTTGTATATCTGCAAAGATTTCATACTCCAAGACCCAGCGCAGTTTTGTTCATCTATTAATTTAGTGTGTCTATGTGACCTTGAAATTCCAACTGAGTTGACTTCTTGTGATATGCTCAATCTTATTTTAATTAAGAAGCCGGTCAGCGTTAATACGTTATATGCGCGGATACAAAACATTATCCTCACATCTAGTGATGAAGGTTATATTCCTCAAAAGCTTTTAGACGCTGCATGTTCCGGAAATCTGCAAACCATTGCGGACACAGCTTGTTCCTTACTTGGAAACCCTATTATAATATATGATTTAGGTTTTCAAATTCTTGCTTTTTCTCAAAACTTAAGACCTGAGAATGAGATTTATAAAATGGCCGGACAGGATGAGCAGATGATTCAACAAACAATGGCAGCTTTTTTTCAGGTAAAAGCGTTAGATACGATGCGAGAGAAAGGTTCTTCCTATTTTTGGAAGTGCTACGGCCATGACAAACCTTTGCCGGAAGATACCATACTGATACATGCGCCCATTATGTTGGATAAAGTTATCATTGGATATGCAGTGGTAATGAAAGGATATGTTGATTGGGATGAAAGCGACCTTATTCTGACTGATAAAATATGCAAGATTATCTCCCTTGAAATGAAAAACAACTACTTTAATAAAAATATCAAGGGTATGCTACATGAGCATTTTCTTAGGGATATGCTGGAAAATTCAATTGAAAAAAGAGAATTTATCGAAGCACGAATCAGCACCTTGAATTTGAAATTGAATAAAAATATTTATATGGCTGTGATTCAATCAGTAAATCCAACTCATTTAAACTCGCAATTACATCCAATATTAAAGGAACTAGGAAAGATTTTTAAAAACAGTATTTTTGCCGTATACACAGATCATATTGTATTGATCCATCATAATAATGAAAATCAGGAATTGACGGGTCAGGAGCAGGAGAGGCTCAACACTTATCTTAACGCTTGTGATATGGCTGCTGGTTTTAGTATGTGCTTTCACGATCCCTGTCAAATCAAGCGACATTATCAACAAGCAAAAGATGCTCTGGATATTGGTTTATCTTTACAAAAGCCGGGAAAAGTTTTCTTTTTTCAACAACTATCTATTTACCGATTGTTTGAATTGGGCAACAAGACTACCGATATTACGGATTATTTGCATCCAGCTGTATTTTGTCTGGTAAACTACGATAAAGAAAACCATACTGAATTTATGAAAACACTATACTATTATATTATTAACCTAAAAGCTTTATTAAAGACGAAGGAAATCCTTTATATTCATCGAAACACCCTGGTTTACCGCATTAATAAAATTCAAGAAATCACAAACATTGACCTACACGATGGCGAAACATTCTTTCAGTTATATATTTCCTTTAAAGGACTTGAGTTTATAGCACACCGGACTAACAATAAAATAAGTTTCTTCTAGTTCGATATAAAGCTTCTTGCTAAACAAAAATACCCTGCCAGCTACAAAGCTGGCAGGGTATTTTTGTTTGATTTAACTTTATAGTATGAAAGTACAAATTGTGAAAATGATCACGATGTAAATTCTGTACCATGATATATGTTGCCGAAAATTACAAAATGATAGCATTTTTGTGTAGTACAAAATATATAGAGAAAAGGAAGAGTACTAATGAGCGAAAACGAGAAGAAGGGGTTAAGTCGAAGGAACTTTGTTAAAGGAACAGCAATTGCAGCTTTGGGGGTTGCTTCCGCGGGACTACTGGCTGGTTGTTCCGAGAAAGCGGATACTGCACGAGCTTCTGCAGAAACTTCGTCCGAAGATTGGCTGGGTAAGGCACCTGAAATTTCTGATTCGAAAATTAAACAGACTCTTAAAGCTGACGTGGTGATTGTCGGGGCTGGTGTAGCAGGAATGCATGCGGCACGAGCAGCGTCGGAGGCCGGTGCCTCAGTAATTGTTGTCGAAAAGGCAGACACATTCCAAGTCCGCAGCGGTCAGTATGGAATCATCGATAGCAAAATTCAAAAGTCTCTTGGAGTCAAGATGGATAAAAACGCTGCAATTACCGAGAACATGAAGCAGATGGGTTACCGTGCAGATCACCGTATGTGGAACTACTGGGCTAATCATAGCGGCGAGGACTTTGATTGGCTGATGGAACTTGCACCTGACCATGTGGTTCTTCCAGAAGATGCACTCTCATTAGATGTAAACAAGATTAATATATCAATGCAACACTTTCCAGTACCCGAGGGTTACAATCCCGCGGAGGAATACAACCCTTCATACCCGACGGTTATGGCTATTCTTCCGAGTCAAAAAAAGCTTATGGAACGCGTACATCAGAAGTGTTTGAAGCAGGGATGCAAGTTTATGTTTAAGACGTGGGCAAAAACGCTCATCCGCCCTAACAATAAAGGCAGGATTGAAGGTGTCATCTGTCAAGACATAAAGGGAAATTATATTAAAATCATCGGTAAAAAGGGTGTTGTCCTTGCGACGGGGGATTATGGCAATAACAAAGACATGATTAAGTATTTCGTACCTTGGGCGGTAAATTTCTTTAATGTTTATCCCAGCGTAGATGCTAATGGTAACCCAGCCAATACAGGCGATGGACATAAGCTGGGCGTCTGGGTCGGGGCAAAGATGGAAGACGGTCCCCATGCGCCGATGACTCACACACTTGGTGGTCCTCTTGGTGTTGATGCGTTCTTTTTGGCTAACACTGTAGGAAAACGCTTTATTAACGAAGATGCCGGCGGCCAGCAGTTGTCAAATGCCCTATATCGCCAACCGGGCAATTTTGCGTGGCAGATCTTTGATGATAAGTGGCCTGAACAGATTGGACTCATGAATGTTTCCCACGGAAGCGTCAACCACTGTGTTGCTGCTGATAAGGTCCCTCATTTAAAGGACTCCTCTTGGGCTCTTGGCAGGGTGTCAATTACCTCCCGTGAGGAAGTTCGGGCCACTGATGGCATTGTTATCGCCAACAGTTTAGAGGAGTTGGTAGGCAAGCTTGGGCTGGATTCAAAGGCGCAGGCAAGGCTCCTTGCGTCCATCAAACGCTACAATGAGCTATGCGGTAAAGGCGTGGATGAGGACTTTGGCAAGATGGCGAAGCGGTTATTCCCAATTGCAAATCCTCCCTTCTATGCTGGTAAGATGGCCGGGGGCGCTATGCTCGTCAACATGGGCGGATTGACCTGCGACCCTGAAACGGGAAATGTTCTTGATAAGGATTACAAGGGAATTGAGGGCTTGTATGCAGTGGGAAACGTATCGGGTGGACGCTTTGTTGGTGACTATCCTACCGTCACGGCAGGTACAAGTCATGCATTTGCCCTCACTTACGGACGTCTCGTTGGGATGACAGTTGCCAAGCTCTAGAAATTTTCCCGTAATAATATCCTGAAGATAAATAAAACTCTGAATAGGAGGATAGAAAATTGTTTAAAAAAATGTCACCCAAACCAGAACAAATAAATAACGAACAAAAGCTTTTTAAAAATCTGTCAAAGAAACAAATAATCTTTCTACTATTGATTGTACTTGCCTTTGTGGGTCTAGGAGGATTGGCAGTCGTAAAGGCCAGCGATAACCCAGCATTTTGCAGTACCACCTGTCACAATATGAAACCACAGTATAATTCGTATCAAAATAGTAGCAGTAATTTGCTAGCTTATAAACATGCCAAGGCTAAGATTGTATGTCATGATTGCCACCAGGACTCACTTACGACAAAAGCTCAGGAAGGTGTGAAATATGTAACCGGAAACTATGAGGATCCAATGAAAACGAGAACCTTTTCAAAAGAGATGTGCTTGAAATGTCATGATTGGAAGAAGGTACAAAAAAAGACCGCATCGCTTGGAACAAAGGCAAATGAGAATCCGCATAATTCAGAACACGGTGGTCAGCGGGAGTGTAGTACCTGCCACAAAGTACATGAGCAATCAACCAATGGATGTTTAAAATGTCACGGAGCCTCATGGGCGAATAAATTAGATATCAGTTGGAAGAAGAAATAGTAATAAAAAGATTTACGTAAGATGGAGCCGTTTTACGTACGGCGTTAGTTTAATTGGAGCTCAGTTAATAATAATTTTGTGGCCTCATAATAAGCTTTGTAAACAAGATAAGGATCATGAAGTTGGATAAGTTTCCAACTTCATGGTCCCTAATGAAAATTTGCCATATTACGTGTGAAAGTGAAGTGGATTAGTATTTTCCTATAGCCATAGGTGCAATTGAAACTAATAATTCTTTCCATAGTTTATATAAAAATAGAAAACCTATTGATATGGTAAAAAAGTTAATTGTCTCAACCTAAAAAGGAGATGTTACAAATGCTTTCAAACATTGGAATACCTGGGTTAGTCTTAATTTTTATTTTGGCACTTATCGTATTTGGACCAAAGAAATTGCCTGAACTTGGCCGTGCAGTTGGACAAACACTCAGTGAATTTAAAAAATCTGCAAGAGACCTCACAAGCGATATAGTCAAGGAAATTGATGAGGCAAAACAAGATGCAACTGTACAAGTACTTACAAGTGATGTAGTTAAGAAAGTTGATGAGGTAAAAAAGATGTAACTAAATAAGGTGTAAAATAATTGAACCTGGAATCGACAAATCCAATGTGGTGATGAGTTTAGCCATACCGATTCATTAGCGGTATGGCTTGGAGGGGAACGAGGTTTTCAAAAGGACACATGGTACAATTTTACTGATTGATGAGGGAAAAGAAGGGGGATGAAGAGTGATAGATAAAGAATTACTTTTAGTCGATCATTTAGAGGAATTACGAAAGAGAATCATCCTATCCGCTTTAGCATTTCTATTCTCTTTTGTAGTTGGATTTTTCTATGCTATCGATATCTATAAATGGTTTGTTAAAGATCTTGATGTAAAATTATTAGTTCTGGGACCAAGCGATATTATCAGGATTTATTTTATGCTCGCGGCTGTTGTTGCCATTGCTGGGACCATGCCTTTTCTTGCCACACAGATTTGGTTGTTTGTAAGGTCGGCTCTAAGGGCAAAGGAAAGGAAGATAACACTAACCTATATTCCAGCACTCTTTATCTTATTTATTGTTGGACTTGCTTTCGGATATTTTGTCATCCTTCCTATGATCTTTAAGTTTCTCATTCAGCTTGGCGGGGCTATGTTGGTTACTAATTTTACAGCGGAAAGGTATTTCAAATTTATTATGAACATGACGATTCCATTTGGAGTTTTATTTGAATTACCTGTTGTCATTATGTTTCTTACTTCACTGGGAATGATAAATCCTTTTGTCCTTTCACGGATACGTAAATATGCTTACTTTGTACTTATAATTATAGCAGTAGTTATTACTCCGCCTGATTTTATGTCAGATTTTGTTGTTACCATCCCATTACTATTACTTTATGAAATAAGTATCACTTTATCAAAGTTTGTTTATCGGAAAAAATTAAAAGGAGAGAAAAATATGAAAGACTTGGATCTCGATTGTTTAATGGAATAACTTTCAAAAAAAGGTTTGAAATAAGAATCCTTTTACCGAAACTTACCTCTATTATATGGGTATAAACTAAATTATCTCCATATTTCTATGTTAGATCATTACGACCCATCATATATTCCCCCCCAAAAAAACCTGTGTAGAATAAGTTCTACACAGGTTTTGAAAATCCTATTAGTTTGTTAACAGCTCCATAGTGGCTCATTTTTTTTGGGTGATTTTTCTTAATTTAATATGCAATCCAATTAATCTGATACCAGACCCAAAATCAAAGGTTGCGAGAAAAACAAGGATGAACCCAAATATATCCCAACCATCAGTATTAACACTGTCAACAGCAAAATAAGTGAATAAGCATGCTATAAGTATATGAACGATGCCAGAAAACAAAGGTGATTGTCTCATAAAAATCCTCCGATAAAGCTTTGAATTTTTTCAACCTGGTGTAGCATTCTTTCAATGTCTTCTCTATATACGGTTTGAATAATTACAACGAGAGTGTTCATGGTAACATGGGCAATGATTGGGACGATTATCCGTTTTGTTTTTACATATAAAAAAGCAAAGGAAAACCCGATTGCTGAATACAATAAAACGTGTTCAAATTCAAGGTGTGCTAATGCGAAAATGACAGAACTGATAAGAGCGGAAATAAAGAAATTAAATCGTTGATGCAAAGCCCCAAAGATAATTTTTCGAAACACAATCTCTTCTAATATTGGACCAACAATGGAACTAATAAAGATGACGATTGGGAAGCTTTCGATAATCCCAATGATGTGTTGCGTATTTTCAGACCCCGTTTTAATTCCCAGCATGGCTTCAATATTTGCAGCAACCGATTGAGCAAACAATGCTAAAAATACCCCGAATATAGCCCAAATAACCAATGAGGTAATACTAGCCCTATTTTTTTCAAAGCGTGTATCGGAATCATTTCGCAATACCAAGAGTATAATCAAAAGGGTAATAGCAAAGCTTATGACAAGCCAAAAGGGGACGGCTAAAACCTTCATCTCAGCCATTGTTTTTCCGAACAAGGTTCCAATATAGACTGTGAGGGGAACCCCGATGTAGCTAGACAACTGCATGGTAATGTATGTAATTAAGACAATCCAATATTTCTTTTTCAATATATTTTACTCCTTCTAATAAAAACTGCGATAGTAATCCCATTTTACTAATAATTGACCCTATGTTTCAAATTAACAAGTTTATTCTTAGTAAATTTTGTGAATTTGAATAAAAATAAAATTGTGTTGAATACTTTATAAGGTTGAGAATTTGAGGGGAAATCATAAAAAAATTTGTGCATGGCACTTGCAAAAGACTGATAAATTATTTACAATATTAATTGTGTTAGCACTCGTTAGAGGAGAGTGCTAATAATTGATAAATTACATATTATTTGAGGAGGTTGTTTCTCTTGTTAAAGCCAATTGGTGATCGTATTGTTATTGAGCTTGTTGAATCAGAAGAAAAAACTGCGAGCGGTATTGTACTTCCTGACAATGCTAAAGAAAAGCCACAAGAAGGAAAAGTTGTTGCAGTTGGTACTGGTCGTGTTCTTGATAGCGGTGAGCGTGTGGCAGTAGAAGTTGCTGTAGGCGATCGCATTATCTTCTCAAAATACTCTGGTACTGAAGTGAAATTCCAAGGTACAGAATATTTAATCTTACGTGAAACTGACATTCTTGCTGTAGTAGCCGAATAATTTAATCAGCAGAAACCAATCGAATATAAAATTTAGAAATATTAGAGGAGGTTATTTTACGATGGCAAAAGAAATAAAGTTCAGTGAAGATGCACGTCGCGCGATGCTTCGCGGGGTGGATGCTCTTGCAAATGCAGTAAAAGTAACTCTTGGACCAAAAGGACGTAACGTGGTTCTTGAGAAAAAATTTGGTTCTCCGTTAATTACAAATGATGGTGTTACCATTGCTAAAGAAATCGAATTAGAAGATGCTTTCGAAAACATGGGAGCTAAGCTTGTAGCAGAAGTAGCAAGCAAAACAAATGATGTTGCCGGTGACGGTACAACAACTGCAACGGTTCTTGCGCAAGCAATGATTCGTGAAGGCCTTAAAAACGTAACAGCGGGTGCAAATCCAATGGGAATCCGTAAAGGAATCGAAAAAGCTGTTATTGCTGCTATTGAAGAATTAAAAGCTATTTCTAAGCCAATCGAAGGCAAAGCGTCTATCGCACAAGTTGCAGCGATTTCTTCTGCTGACGAAGAAGTGGGTCAATTAATCGCTGAAGCAATGGAGCGCGTTGGTAACGACGGAGTTATCACAATCGAAGAGTCTAAAGGCTTTACAACTGAATTAGACGTTGTAGAAGGTATGCAATTCGATCGTGGTTACGCATCTGCCTACATGGTAACAAATACTGACAAAATGGAAGCAGTATTAGAAAATCCATATATCTTAATCACTGACAAAAAGATTTCTAGCATTCAAGAAATTTTACCAGTGCTTGAGCAAGTGGTTCAACAAGGTAAACCATTATTACTAGTGGCTGAAGATGTTGAAGGTGAAGCATTATCAACATTAGTAGTGAATAAGCTTCGTGGAACATTCAATGCAGTAGCTGTTAAAGCTCCTGGCTTTGGTGACCGTCGTAAAGCAATGCTTGAAGATATCTCGATTTTAACTGGCGGTGAAGTGATCACTGAAGAGTTAGGTCGCGAACTTAAGTCTGCAACAATTGCATCACTAGGTCGCGCTTCTAAAGTTGTTGTAACAAAAGAAAATACAACAATCGTAGAAGGTGCTGGAGAAACTGCAGAAATTGCAGCTCGGGTAAACCAAATTCGTGCTCAATTAGAAGAAACTACTTCTGAATTTGATCGTGAAAAATTACAAGAGCGCCTTGCTAAATTAGCTGGCGGTGTAGCAGTCATTAAAGTGGGTGCTGCAACTGAAACTGAATTAAAAGAGCGCAAGCTTCGCATTGAAGATGCATTGAACTCTACTCGCGCAGCAGTAGAAGAAGGTATCGTTTCTGGTGGAGGTGTTGCCCTTCTAAATGTATATAACAAAGTAGCTTCTATCCAAGCTGAAGGCGACGAAGCAACAGGCGTAAACATCGTATTACGTGCGATTGAAGAGCCTGTACGCACAATCGCTCACAATGCTGGTCTTGAAGGATCTGTTATCGTTGAACGCTTAAAGCGTGAAGAAGTTGGAACAGGCTTTAACGCTGCTAATGGCGAATGGGTAAACATGATCAAAGCTGGTATCGTTGACCCAACTAAAGTTACTCGTTCTGCTCTTCAAAACGCAGCTTCTGTTGCGGCTATGTTCTTAACAACTGAAGCAGTTGTTGCTGACAAACCAGAACCTGCTGGTGCAGGTGGCGGAATGCCTGATATGAGCGGTATGGGTGGAATGGGCGGCATGATGTAGGAGAGACGTTTGAAACGTTGATATATCAAGGGTTATAGACTCTTTTATGAGCCTTTAACCCTGATAAAATCACATTTCAATCACATTTCTTGCGATTTTGCTAAATTAAGAATGCTTCCGAAATGATTTTTAATCTTTTCGGTGGCATTTTTTTTCATTTTATCTGTAATGTGAGTATAGATTTTCATCGTTGTTTTCATATCGTCATGACCAACCCTTTTCATGATTGTATTAATATCAATTCCAGCCTCGGCCAACATACTGATATGAGAATGCCTGAAGATATGAGGGGTAGCATTTTTTTGTATTGATGTTTTTTTAAGCAGGCGATTCATTCGGATAATGATGTTTTTTTGGATAAAAGGATATCCGTTTTCACGGCAAAAAATAAAATTCTTATCGTGGTAGTCAGGATATTTATGCCTGTTTGCCATTTTTATCTTAGCTTGATTTTTTTTATGGGCTTTCAATAAATCAATTATGCTATCATCAATATCAAAAGTCCGGATAGATCCTTTCGTTTTGGGTGGTGTCAGTTCGTATTTATGCATATTATTATCAGGATTGTATAGAGTCTTGGTAATTCTTATTTCATTCGTTTCAAAGTCCACGTCAGTCCACTTCAGAGCGCACAGCTCACCAGATCTCATCCCCGAAAATGCAAGTAGATAGAATATCTCCATATCCATTAAAAGACCATACTGATGTGCTGTAGATAGAAATTCGGATAGTTCATCTTTTTCTAGGTATTTTTCCTCTATCGTGTTGTTCTCGATATCCTCAACCGTTAATTTTTTCACTGGAATGACAGATCCGGTGCAAGGGTTATCTCTTCTCATTTTTTCCTTGATGGCAAAGTTAAAAATCATATTTGCCGTAACATGAACACCTTCTATCGTTGTTTTGGCGTATTCTTTGTCGTCAAGGTCATTTAAGATGTTTTGATGCATACGTGGACTAACTTTATCAATATTCACTTTTGCAATGTATCGTAACAAGATTTTAATTTCTTTTTCCCTGACACGAACAGTACTGGCTTTAACTTTACCTCTAGAGTAGGTATTCAGCCACTCCAGTGCTACTTTTTCAAAGGGCAGATTTTTTATTTTTTTATCATCTATCCCGTGATCTGTTAGTTTTCTTATTGCTTCATCGACCTTTGCTTCAGCTTCTTTTTTTGTATCCCCACGTCTAGGTATCTGATTACGTTTCCCAGTGACTGGATCAGGTGGACCATCTTTAACACAAACCCATTTATAGCCCTGCTTGTTATTTGAATCAATTTTCCTAAAGTAAGCCATGGATATCTCCTCTCATTATAGGATCTCGTGTTTTTCTTTGTATCCTTGAAGGACCTCTTGTTTTTCATCATCTGGCCAGTCTAATTGATTAATAAACCTCTCAAATTTAGTATATTCATCGATATCGTCATCAAGATAGATAATACCTGGTTCTTCATGAACCACTGGTATATCTTCTAGCATTTTTATATACTCTCGGTGGAATAATTCACCTGTTACCCGGTTCTCGAACATTTCTAGTCGTTTCTTTGCAAAATCTATGGTTACGTTAAACGTATCAGCGATAAGATTAATTGTTTGTCCTTTCGTTCTAGGAAATTCAATATTCATCAACATAAAAGTAGGAATGCAAAAGTGATACATAAAATTATTTGCTTGATGCTCTTGGAGCTCAATAAAGCTTTCTGACATAATTAACTGATTTCCATTATGTCGCAAAGCATGACATAGCTCATGTCCAAACTCTTGCCATTGTTCTTGAGAGCTTAATCTCTCATCAATGATGACTTCTTTATGATAAAATCGACTGGAGATATCTTTAAATATCAAGCTCAATCCCATTCGAAACGAAATATCCAATAAATCAAGTTGGTGTGGGTGATAAATTTCTAATTTAAAATAAAAATCTTCGATCCAATCCTCAAGTAAAGTGGTTTGGTAGTCCATGGTTGCCTCCTGAAAAACGAATTTATGTTCGTTAATTGAGTGTGAAAATGACCAATTATCTTTTTGTTTAGTAATATAAAAATAAAATAAGAAGTACTTAAATATACTTTAGGAACATATGTTCTATATGCATTATATATTTTTATAACAAAATAAAAAAGACATTATTTGGTTGTAATCCAAATAATGCCGTAGTCTTTCTTTGACTATTTATTTTTTAGATAATAAAATGCTTCAAAGCCAATATACCCATCATGTTGTAGCCTTGCTACTACAATACCGGGGAGTATGTTTTGCGATAATGAAAATTCTTCGATACTTTTCTGATTAAATATTCCTAACTCAGTAAATTTTTTATAGTCTTTCTTGTCTATAAAAAAATCTCTTGCAAATTCATTAGCTTCATCTTCTTTTGTAGAAATCTTATTATCCAATTCTAATTCAGACTCAAATGTTATGATTGGTATATTTGGTTCATAATGCATTATTAGGTGTCCGATCTCATGCATAAGAGCAAACCAAACATGATCATGTGTTTTAAATCTTCCACTTAAATAAATAGCTGGATTTTTCTTATAGGTTGTAAGAGCACCTCTAACTTTACTGTTAACTACTGCATCACAAAAAACTAAATATATACCTAAGCGATTTAACAACTTTCTTGCGCTCTGCAAAGAGCTTTGATAATCGTTGTTTAAAGCAATTCTTTTAAATTTTTCCAATGAATTAATTAAGTTTGTTCTATCATATTTTTTATTTGACAAATCGCGGTTTTGAATTTCAACTTCTTCTCTTGCTAAATTCAACCAGATTGCAATTGATTCCTTTTCGCCACCATCTTCCATAAAATCAACACTCAGATTAGAATAAACGTCATCGAATAAACTATAATTACTTATACCTAGGAGCTTTAGCATTTCATTTGCTTGTTTTTTCAAATCCCAATCTAAACCTGCGAAAACAGTAGAAAATTTAAATCTTTTATCCAGTTCTATCAATTCTTTTTCTTTAAATTCTTTTTGATTTATTTCTTCCCTTTTTAGGTATTCTCTGTATTTGCTTTCATAATTTAACCAATAAGATGCGGGGACATTATGAAATATTTTTTCAAATTTAATAGCGATATCCTCAGTTAATTTAGTCTTTCCGTTCAAGAGATTAGAAAGATGTTTTTCACTAATTCCTAACCTCTTTGAACAATCTTTTTGGCTCATTCCAAGTTCATCTAGATATTCTTTAATAATTGCCCCAGTGTGCACGATAAAGTTCTCACCCATAATAATACCTCCTTTCTAGTGATAATCCTCTATTGTCAAGATTTCTATGTCACTAATTGTTTTGTGATCTTGTTCATCCCATTCTCCAACCGGTCTTAAAACAATACGGTAGTTCTTAGAAACAGCAATTCCCCAACAGTCTTCATACTCCCCAGTTAGTTTATGCCGACAAGGAGGGGGATCGTGAGAGATTTCCTCTAAATTATTCGCAGCTGTTAATTCAGACATCCTGTTAATAACATTTTTATAAAAAGCAGTATATTCTTTTTTAATTAAACGTTGATTTGTCAATATTCTCTCTAACTTATTAGAGGTGTAAATAATGTTCATCTTTATCCCCCTTACTCTATATATTGAAATTAACATAATTAACCTAACAGGTCAATTTCGCAGGTGTAGACTAACATCTAAAAAATATATATAATTGCGATAGTATAGGAGTGCATATTATGCAAAAGAATGATTATTTTGAATTTGCGAAATTATTATCAAATCAATATTTTACTTTTTTGAGTAATGAAACAATTAAACGTGAGGTTTTAAAAACATTCAATGGTCAATTGCCTTACGACCAGAATAATAGTGATTTAACACCAAGGGAGTTCTTAAATCAATTTATCTTACACTATTACCCTAATGAAACCTCTGTTAAATCTACATTCATAAATAATGTGCTTTTTAAAACAAGCAATCATGTTTCAATATTTGAATTGAATGTAGGCAAAAGTAGACTGGATTTATGTAAAATAAATGGTTGCAGTACTGCTTATGAGATAAAAACGGATTTAGATACCCCAATTCGCTTAAAACAACAAATGATAGATTATTTTCAGGTCTTTGAAAAAGTCTATTTAATTTGTTCAGTACAGAATCACGATTCAATGGTACCGTATATTCCAGAGGAATGTGGTATTTACACCTATTACAAAACCAATACTGGTAAATATGTTTTTAAAAAGAAACGTAACGCTGTATCTTCAACTAGCATATCTCCTCAAGCACAATTGTCTGTCTTAACAAAAAAAGATTTGAACACATTCTTTCAGTGTCCAAATCTTGAAACTAAAGATGCTATGATTGATGTAATAACTAGTTCAAAAACAAATAAAGAAATTAACAAAATTTTTAAATTCATATTAAAAACCAAGTATTATGACAAATGGAACTTTCTTGTAGAAAATAGTGATGAAATTTTAGAAATCGATTACCAATGGTTTTTTAAAAATTTATTATCACCTGAAATAGTGTACCTATAGGTACACTATTCTTGTGATTGTTGTTGTATATATCGTGTTAATGTTAGGTTATTCCAAGTTCCCCAGCTACCGAACGTTAATCCCATGTCTTTTATTCTTTTTATAGCCAGACAATGATTTTCTCTATCTAGGAGATTTAATCTTTGTAAAATTTCACTTCTAACATACTCATAACCTCTTACTCCTTTATCAGTATCATGGTTTACTACTGAGAAAAAAGCATTTTTTTCTTTTAAATAAATAAGTCCTAATGCCGATCCCTTCCCATTACTACCACCTTCTTCGGGTAGAGCGTCTTTTAATCCGCCAAAGTCCCCAAAGCCATCTAAATTATACTCTTTATATATATTTGCGACTTGATTATTAATTTTACCTGTGAATACTAAATTTTCGAAATCCCCATTTTTATGAGTTTGGGATCTAGGAGAATTAAGTAGAATTTTTTTTGCATCGGTTTCTAATTCCTGGAACTCCTCTAATTCTAAAAATTTTGAATCAGCATTCTTATCCCTTATATCTAACATGATGTAATCAGAGCTTCTTAGATGAGTCTCTAATAATTCTGCATATTCTTCTAGATAATAGTCCGTAATCCTAATTACGATAGACTGATTATTTAGTTTAAGGTCGTTTATAAATTTAATTAAAATATGAGGACCAATTTTAAATCCACTTTTTATGGAAATTACAGGTATAAGATTAGCGTAATTTCCAATCTCGAGCATTCTTTGTCTGTAGTAAGCAAAGTCCCTGCTTAATCTAAATGCTAATTCAATATTTTTATATGTCTTTTTTTTATCATATTCACCTTCACTAAATCGAAAGAATTCAATAAATGCTTTCTTACCGTTAAGACGTTCGTTAATTGCTTTTAGGGTAATTATGTCTGCTTCAGTGGGTGGTATTCCAATTCTATTTCTTCTTGTTTTGCCAGCTTTTTGCTCATATATAAACTTTCCAGTGTTCTCATCAATTTCATATTTTTTTTCATGCTCATCCTTAATAAGTTCAATTAGAGGAATCATTGAATCATTAAAATAACCATTCATATTTTTAATAACTATTAATTCTTCTTTACGATTTTTCATAATAGGTACATACATCTTACATCATCCTTCGTTGTTATTTATAACAAAACTATGAATTTAGTAAAAACGACCAATTAATACAATTTTCGCAAATAAAAGTAAAAAATGTACACGTTCACTAGATAGAACGTGTATTTACCGTCAACATATTCTCAGGATGACCTATTTAGATGATTGTCTATTTTTTATCCCGTTCCTTAATGAATTCCCAGAAACGAATTAATTCTTCTATTTTTTCTTCTGGAGCATCCATTAAGTCTTTAAAGAATACCTGTTTTTTAGGGTCAAGTAATTCTCTCCACATTTCATCACTTGAATTACCGTTTTCATTACCAGTTACAAGGTAATCAATTGATACTCCAAAAAATTCAGCCAATTTTTTCAGGGTACTAAAATCAGGCTGGCTGCTATTTTTTTCTTCATTTTCGTACTTACCATATCCCTGTCTAGTGATGCCTAGGAGATCAGCCATGTACTGCTGCGAGAGTTTCTTATTTAATCTTAATTTTTTAAGTCTGTCTGCAAACATATTTATTCCTCATTTCCCATTACTCCTAACAATATTATACAGCAACAAATTGTTGCTTTCTATTAACGTAACTAAAAGTTTCTAAAAATAGTTGACAGCAACTAAAAGTTGCGTATAATTAAAAATATAAAGCAACCGTTAGTTGCGGATGGGAGGTGTAATGATTGAGTCCAAAAGATCTTCAACAACTGCTTATCAACAAAAGAGAATATTTAGGCCTTACTCAGCAAGATGTAGCGGAACAATCTGATGCAGAAATAACTAGACAATACTATGGGATGATTGAAAATGGTGAACGTAGACCTTCTGTTGATGTAGCTAAAAAAATTTCAAATGTTCTAGGTGTTGAGTGGACAATTTTTTTTGAAATTAACAGCAACCAAAAGTTGCTTAATAAAAATACAGCATAAGGAGGTAAGTAGATGTTCACGCTTCAATACGATGATCAATTCATTGAAAAAATTGCCGCAAAGATCGCTGACCGTGCTACTGAAATGCTTGTTGAAAGAATCGGTTCATTCAATGATCTTCCTCTAGTTTTGACTAGGGAGGAAGCTATGAAAGTTCTTCGGTGTGGACCAACAAAAATGGCTGAGTTAATGGCTAGACCTGATTTTCCAGTATCAAGAGAATTCGGCGTTAAAATACCAACACATATGTTAACTAAGTGGATAGAAAAAAACACTCGCTGGATGGAAGCAAATACTGGCTACTTCAATAAAGCTATCTAATACTAGCTTATCAGTTTATTCCATATTTTTTGGCAGAAATGGGGGTGTGAGAAATTGGAAATTGGCAGAGCTGCTATGGCGGCTAAGTTAGCAAGAAAAGAAACTGGACTCACCCAACAACAAATGACCCTTGATGAATATTTTGGATCTCGTGAGTCCGTATCTTCTCAAGAAAATGGTCGTTATCAAGTTCAACCTGAATTAGGAAGATATTACTCAGAAAAACATAACGATCCATGGGTAGCGATGGAAGCGGCAGCAGAATACACCGGCTGGGGAATCGTCAAATTAGATGGTGAGGCAGCAGATTTACATAGGACGTCCGTATCGCTAAAGACCAGAGAGGAACTTAAAGAAGCGTTAGAAGCTGTTATGGATGCCTCGAAGAACCTTACCGTCAATCCAAAATGCGTTGAGAGGGTTGAAATTGCGGTTATTGAAAAATCTCTTCATGAATGTATCGATGCGATTACCGCGCTCAATCATTATGTTGCAGTGATTTGTAAAGAGTATGGAATTCCATGGGCTAAGATGTGGACCCAGCACAAGATCAAGTTGATCCAAAGGAGGTTTATAAAAAAGTGAAAAAAGATATTACTCATCGAATTGCTTATTATGTGCGAAAGGTTAATGAAAGAATGTCTTTTCATCCATCCAAGAAGCTACCAGCTAAGTACACATATCGTCATGAACGCTTAATGGCTTATAAAAAGCGAATGTTTGAATTGATTGAGGAGGGAGAATACAAAAAATGTTCGGATTGACACCGGAACAATATTTCTTGTTTTTATCAATTCACATTAATCATTTAAAAACCATAGGTACTGAAAATCAAAAGAAATACTGTTTATCGAAAGTCAGAAACGTCGAATGGGATTCTAAAAGGAAATGTTTAAACGTCTATTATGATGATACATCGTGGAAATACGACGATAATGGCTGGTACTAAAAAGGAGGTGAAAAATAAATGAGTTTTGTTCTTAGTGTAAGCAAATTGATGAAGGCTAGTGAGGTTCGTGAGCTTTGTAAGGAAATGAGGGAACAAAAGCACATCTTAGCTAAACAAGAAGCGATTGTGAAGGCATTGTTATTCAGCAGAAATAAAAAAGCAGCAAGCTAAGGCTGGCACCTTACTTACTGCACTTTGAAAAATTAAGTTACCTCTATTTTACCACAATTAAAAAAGGGAGGACAAGCTTGTGTTTGATACAAAGAAAGGGCCTGTTTATGAGCCTGATCATCCAGCACTAAATGGCATGTACGAACTACTTAAAAAAGATGCTGCTACCTTATCTGGAAGTCGATTATACGAAGATTTAGTGGATGTATATGAATCAATCAATATGGATTTGAAGGAGGAAATGGATAATGGTAAAACAATTAAGGCTTCTTAGTCTTGAACTAAATAAGTTCAAAGGTGTTCCGTCGTTTTTACTTGACGCAAGAGGTGAAAATGCAAAGGTATATGGTGACAATGCAACTGGTAAGACAACATTGTTTGATGCATTTATGTGGCTCCTATTCGATAAGGACTCTCAAAACAAAAAGGATTTCTCCATCAAAACTCTAGTCGATGGAAAAGAAGTTCACATGATGCAACACGAAGTTGAAGGTGTTTTTCTACTTAATGGAAGAAAGCTTACATTGAAAAAAGTATTTGCGGAAAAGTGGACCAAGAAACGTGGATCCATTACTCAAGAATTTACTGGCCATACAACGGATTATTTTGTTGATGGTGTTCCTTCTAAATTAAAAGAGTACAAAACACTTGTTGATTCAATTGTGAACGAGAATATTTTTAAACTTCTGACCAGTCCTAGTTATTTTAACGAGCAAGTTAAGTGGCAGGATAAGAGGAAAACGTTGCTTGAAATATGCGGTGATATATCGGACGAAGAAGTCATTGCAAGTGAGTCGTCTTTATCAAAGCTCCCAGCTATATTGCAAGGCAAGTCAATAGAGAATCATCGAAAAATTATTGCTGCTAGGCGCACTGAAATTAATAAAGAGATAGAAAAGATTCCGGTAAGGATTGATGAAATAAAGCGTAATTTACCTGAGTTAGATGGTCTTGATAAGTCGGAATTAGAAACTGGAATCAATCAAATGAACGATGAAATTGACGGAAAAATGACTCAAATCATCAGTATCAAGAATGGGAACGCCATTACCGAAAGGCAGAAAGCCATTCAAGAAATTGAAATGGAGCTACTTAACATTAAACGTGACCATGATTCAGATTCGAAGGACCTTGTTTATCAGAAGAAGGCTCGAATTCAGGAAGAACAGTCCAATATTTCTTTACTAAAATCAAAGCTTAATCAAGTGAAAAATAACAAGCGATACAACGATGAAAATATAAAAAATATCGAAAATCAACTTGTTCAGTTACGCCAAGAGTGGACTGAAGTAAATAACCAGGAGTTTTCTCATGCAGACAAATGCGAATGCCCGGCATGTGGACAGTCCTTACCAGAACAGCAAGTACAGGAAGCACGAGATAAGGCTCTAGCACAATTCAATCTTAGTAAGGCAAAGAAGCTTGAAGGCATTAGTGAAAAGGGAAAACAGGGTAGCGAGCGCAAGCAAGAGTTCATTCAAAACAATGAAAAACTCACTGTTGAATATGACAAACTAAACGGTCAAATTTCTGATAAACAAACAGCTTTAGAAAAGCTTCAGGAACAACTAAATCAGTTGGAAGGAAACATCATCGATATTAATGAAAATCCTGTCTATGTTGCCAAACTGAAAGAAAAGTCACAAATTAACGCTGAAATTTCAGATTTAAGAAGCATGTCAGATCAAGCTATACAAGATATTCAATCAGAGATCATTTCACTCAAATTAAAACGAGAAGAGCTACAAAAGGATGCTGGTAAATTTGCTCTTGCTGATCAGTCTAATAACCGAATTGAAGAGCTTAAGCAGCAGGAAAGAAAATTATCTGCTGAGTTTGAAAAGTTGGAACAAGAACTTTACCTAACAGAAGAATTTATTCGGACCAAGGTTAATTTACTTGAATCAAAAATAAATAGCCGATTCAAATATGCTCGTTTCAACTTATTTAAAACAAACATAAATGGCGGTCTTGAAGAGGTATGTGAAACAGCGTTTAACGGTGTTCCTTATTCCAGTGGATTAAACAATGCAGCCAAGATCAACATCGGATTAGACATTATTAATACGCTATCTGAGCACTATGGATTTACCGCACCAATCTTCATTGATAACAGTGAAGCAGTAACTAAACTAATCGATACTAAGTCTCAGACAATCAGCCTAGTTGTTTCTGAAGCTGATAAGGTCCTAAGGGTTGAACATGAAGGAAATATTGTTAGGGAGGCAGTTTAATGAGTACACAAAATGAGTTAGCAGTTAAGACAAGTTCAGAGAGATTTCTAAATAACATTCAAGCACAATTTGCCGCAGAAGCAGGAAGCCCAGTAGCCTTTTCAGATTATGAAAAGGCGCTGGCACAACATTTGTTTTTGAAATTAGATTCTGTCCTTCAAGACTTTGAGGCAAAAAGGATTAACAGTGGAAAGACCCAACAAGCTCCTTACAATTGGCACAACATCAATATGAGAAAACTATCACTTGATGCCGTTCACACGGTACAGCTTGGATTAGATGCACTGATCGCTAATCATATTCACCCAGTACCTTATTTCAATGGTAAGGAGAAAAAATACGATTTAGATTTAAGGGTTGGCTATATCGGGAAAGCGTACTACCGAATGGAGGCAGCTGTAGAAAAGCCAAAAGATGTGGTGATTGAACTGGTTTATAGCACCGATCATTTTAAACCGATGAAAAAATCTTTTAGCAACAGCATTGAATCATATGAGTTTGAAATTCAAAAACCTTTCGATAGAGGAGAAATTGTTGGTGGATTTGGCTATCTAGTATATGACGATCCAGCGAAAAACAAATTAATTCTTGTTTCTGAAGCCGATTTTGATAAGTCTCGTAAGGCAGCCAAAGGAGATACATTTTGGTCAAAACATCCTGCTGAAATGAGATTTAAAACACTCGTTCATAGAGTTACAGAAAAGCTTCAAATTGACCCGAAAAAAGTAAATGCCTCTTATCTCTATGTGGAAAATAAAGAGTCAGAAGACGAAGTAAGAAAAGAAATTAGCGAAAATGCTAATAAAGATGTGATTGATGTTGAATTTTCGGAAACACCTGATGAACCGGTTAATAAAGAACCTAAAGTTGAAAATCATTCAGAGCATTTTGAAGAAGCACCACCACAGCAAGAGCAAATGGAATTTGCACCAACTGGCACCGGCGGCCCTGGTTTCTAATGATTGAAATTACCGCACTTGCATCTAGTTCGAAGGGGAACTGTTACCGCGTTACAGATGGTCATACTCCCCTTCTCCTAGAATGCGGGATAAATTATCGAGAAGTTCAAAAGGGCTTTGATTTTCGGTTGTCAGAGGTGGCAGGATGCTTAGTAAGCCATGAGCATGGTGATCATTGCAAGGCGGTTAAGGATGTTTTAAAAGCCGGAATTGACTGTTATATGTCCGCTGGTACAGCCCAGGGAATAGGAGTAAATCATCACCGGATAAAGAAGGTAGAGGCTAAGAAGCAATTCATGCTCGGTTCATGGACCATATTACCTTTTGACGTCCAACATGACGTCTCAGAGCCACTAGGGTTCCTACTCGTGAATCAGAGCGGAGAGAAGCTTTTATTTGCCACAGATACATACTACATCAAATATCGGTTCCAAGGGCTTACACATGTTATGTGTGAGTGTAATTACTCTAGGGAGATCCTTATTCAAAACATTATTAATGGTTCTGTTCCTAAGGTTATGAAGAAACGACTGGAAAGATCTCATTTCAGCCTAGAAGACGTGAAGGATTTTCTTCTTTCTAATGATTTGAAAAAAGTACAGGAAATATGGTTGCTGCATCTAAGTGACAGTAACAGCAATGCTGATCAGTTTAAACGAGAGATTCAAGAGCTTACTGGGAAGATGGTATTGGTTCCTTAAAGATATGGGAGGGATGATAATGGATGGCTGATGTACAACTGGAGAATGGCTACATACGGATTGCAACTGAACTCATTGATGAAGTCATTAGGAGAGATTTTTCTAAGCGACAATTAGCCATCTTGCACTTTATCATTCGTTTATCGTATGGATGCCATAAAAAAGATTGTGTCATTGAAAAATTTAATTCCTTTGAATTAGCTGGGTTAAATAAATCAGATATTAAGAAAGAATTAAAGTTTTTAAGAGATTGTCGGGTTATTAATTGGGATGAGGAAACGATGATTTTTTCTATTAATAAGGATTATGAAAAATGGCAAATTAACCCTTCAAAAGGATTTGACAAAGAAAAACTCAGCCAATTAATACACATCAATATCAAAAGAAAAGTTGGTAAAACACCAACTGATTTAGAAAATGTAGTTGGTAAAACACTAACTGATTTAGGGGAAGTTGTTGGTAAAACACTAACTTCTAAGTTGGTAAAATACCAACTTGAAATGAACGGGAACGCTTGGGAGAGTATGGATGAGGATACCCTTAAAGATAGTATTATAGATATTTATTTAAAGATAAATAAAGAGGAGGAGGAAAAGGCTCTTATGAATCGCATTTTAGAATTACTCCAAAAAAGTAAAATCCTCGAAGAAAAAGACATCACAGAATTTCTTCGAGAGGACATCAATGATGTGATTAATAACTTTGATTTTGAACAGCCTGAGGAAATGATTATTGAAGCAATTAAAGATGCTGCTAGAGGAAATGGCCGAACTTGGAAATATGTATATAAAAAATTAGTTGATTGGAAAAAGAAAGGTATAAAGACTACTGCAGATATTGAAGAGAAGTCTGGAAAGGATGGAGAAAATGGAGCCAAGGTTTACCAGCATCGCCCAGGTTATGGCCGATCTTCAAGCAAAAGCGCAGAACAGGCAATCAGAGAAGCCGATGATGCCCGAAGAGCATGGGGAGGTTGATTACAATTGCCCTATTTGTAAAGATACAGAATTAGTTCTTTACCGCGAGAATGGTTATGAAATGGCGAAATATTGTGAATGCAGGGAAAGAAATGCCTGGAAAAGACGTTTTAATCAATCAATGATTCCAGATGAGTTCACTAACGCAAATTTTGAAAACTTTCAACGTAAATCGAAAACGCTTGAATCTATGTATCAACTAACCTTTGATTATATTCGAAATTTCAAAGTTGAAAAGAAAGAGGACGGATCAACTAAGAAAGTAATCCCATCTAAGAATTTTGGTTTAATCGCAGTTTTTGGAGAACAGAGGCTTAAAGAACTTCCGCCAGCCGAACGGTCAACGGTGAAACAGGAACATAATAATTTTGGTATTGGTAAGACTCATTTACAAATTGCACTTGCAAAACGATTAATCAAAGACGGTTTTAACGTTCTAATTGTATCAGATGTGATTTTTATTGAGGAACTAATGCAGGCCAAGATAATGAAAGATGAGGGAGAGACTTACAACCGGCTATTACATAATACTCTCACTGCAGATGTCCTAATTTGGGATGATATCGGAAAAGTTAGCTGGACTGAACCCCGGGAACGAATGTACTACACCATCATTAATGAACGATACCGCAAACAAAAACCTATCGTGTTCAATTCGAATGAGGACCGTGGGACATTAGCAGAGAAGATCGGATATGCAGCTGCCAGTCGACTGATTGGACAAGCCGAAGAATTTTTGATTGAAGCCGAAGGACAAGATTGGCGGCTGAAGAAAGGGGCTAATGTAAATGCCTGAAATTTGCTTAATAGGATTCAATGGACCTGATCCTTTCTCAATCATTGTTTGGCAACTTGATGGTGTTGATCGAACAAAAACGATTTGCTATACAACCAAAGAAGAACTTAATGCTCTCGAAAGGTTCCATACTGCAGGTGATTTTTATAATCGTTACGATAAGGCGGTTGTTGTATATCAAGATAAGCAATCTGTGGAATATGTCAAAATACCTGAGAAGAAAGGGGCATAATCATGGGAATCTTACTTGAATCTGTTAAAAGCCGAAAGAAAATCAAACGTGGTGCGCCTTTGGAAAAGAAAATGCAATATGTTTTAGACGAGTTAAAATCAATGAATGTGAATATTTCTCGCACTGGGAAGCCTGTGGAGTCACTCGATTATGATGAGTTAAAAGAGGAGTGGGTATTCGCAACCATTCTTAGTTTCGATGTAGAAAGTCCGGAAAATAAGTTTTTTTAGGAGGGTACCAGGTTGAAATTAGGACAACAGGTACGGTTTAAAAAATTCCTTTCCAAAGCAAAAGATGGTGTTTCCTATGGATGGTTATCCGAAGAAATAGAAAAAGAGCTAGAAGATAACTGCCTTCTCAGAGTAAAAAAAATGGCCGAAAAAGAATGCAATGAATATAAAAATGGAATCGTTGTTGGTAAGAGAAAAATAGGGATTGAAACTATTTTGGAAGAAGCACTGGACATCGATGGAGATCCAGTAGATAGATTCTGTTGGAGAGAGACAATCTACGACACCGTTTTTCTTGTAGCTTGCGATTTAAAAGGCTTATACCGTGTTAGAGAAATAGATTTGGAGGAAATAACATGATCTGTCCAATCTGCAATCGCCCATTAAAAAGCCTAAAAAGTATCGCCATAGGCATCGGTCCTGTATGTGTCCGCAAGTTGGAGAATCTAAATGATAACGCTGATGGAAATCAATTGGAAATGGAGTTGAAAGAGAAATGAGCAATGTAAAAACTGTACCCAATTGTCCAAAGTGCAAGTCCAACGGGAATGTTATTAAACACAACAAAGGGATCGTTGCACTTGAATGTCCAAAATGTAAATTTCTTTGGAGCACTTTTTCAGAAACATGCCCAGATTGCAAGAAGCCAAATGGATATTTCGTCAAAGGGCCTTGTAGCACATGTTATTCGCAAAGGCACAAGATTTCATGAGTTCTGCATCAAAGTACGGAAATAGGAAAGTAACAATCGATTCTCACAAGTTCGATTCAGTCGCAGAGAGCAAGTATTACATGCAGCTCAAATGGCTGGAAGCTAATAAACAGATTCTTTTCTTTAGATTGCAACCTAGATACTTGCTCCAGGAGGCCTTCGATAAAGGCGGACAGCATTTCCGGAAAATCGAATATGTTTCCGATTTTGAAGTGCATCACCTGGACGGTTCGATTGAGGTAATTGATGTGAAAGGTGTGGAAACTGAAGCTTTCAAGATTAAGAGAAAGCTATTTGAAAAGAAATATCCTCACAAACTATCACTTATTACATACAAAAAGGAATTCGGGGGATGGATTGAGCTAGAAAAATTGAAAAAACTCGAACGGAAGGTGGTTAAGCCCCATGGCAAAAAAAAGACAACCAAAGTGGGTGCTCCTGTTTCGGAAAGAAGAAGGGAATCGGGTTTACCTATTTGAACCGTTGAAAAAATATGAGCTTCAGAGTCGGATCCGTAAGGGCTGGAAGGTTGTTTAAACAAAAAATTTGTATTAAGTTTCACAGAAACTAAAAAAGGCATCAAACTAGATGCCAATTACTTACTTGAATAATTCGTGAAAACCTAAATTCATAGGAATGAGCCATATGTAAAAACCAATGAGAGCTACCGGACCAATTAGAAAGTTATATAGTTTTTTAGGTAACCACTTAAAAAAAAAGCGATAAACAAAAGAGATACCAACCATAGTAACTATTAGAACAATTAGGGGCCCTATAAATTGCATTGTATTAAACTCAACACCTTCAAATACATTCAATCGTATACACCTCGTTGATTTAATTCATTTATGAATATATGGTACTACGAACTGGGAAATTTTATAAGTAGAGATTGGTGATAAACATTAGAGTAATTGTGTAAAAAAAATTAAAAATCCCTTAAGCGTTATGTCCTGAATGGTAGACACGCTTAAGGGACGGTTAAAAGAAAAGGTAATTCAAGTATATCAAGCTAATGATTTTGTTGGAATAGATGTCACTGAAAATACAAAATTATTAGAAATTAACACAATAAGAAACGCCTTCATTTGACTCCAAGTAGGCATTAAAGTTTTTTTATAAGGCTAGTAAGATTACCCACTTGCCTAAAGGTTGGTTATACTTAGTGATTATTTCAAAAAGGAAGGATTAATTCCTCCATAATTTTGTGATATTAAGTGGAACTATCTCACTTCCGTTTATTTGTTTATGTATTAAAGGATTTTTGAAGGGTTCATAATTTCCACTATCTGTTTCAGAATAACGCGCACGTACATCAACACCTAGGATACTTCGTATTTTATTGTGGTACGTCATTTATTCATCTCCTTCATTAAATAATTTAATATCATTATTATCTTTCTTGTTTATAAAAAAATTCATATTAAATAGCAGAATAAACCTTTCCATTTAATTCCTCAAAGTAAAGAGGTTTCTTTTTACATAGTTCGAAGATTTTGCGTCACAAAGGAGGAAAAACGCATAGATCATGAAATTACTAGTTAAGGACGAATATTGGGATAACTGGGGAAGATTAGTGAAAGTTTTTTGTAAAGGAGACATCTGCAAAGGAACTCTTCGTCACAACGTTAAAGTTTTGGCAGAAAGCCCATATTATCCTGGAGTTTCTGATTATGTCGATTTAAATTGTATCGAAATTTTATAACATTTCATTTCAAAGATTTTATAAAACAAAATAAGCAATGTGTTTACCACTAGACTTTTATTGTGAAGGAGGAAGGAAAGTGAAAAGTGGTTGGATTATTAATTACAAAAACGGAAATAGTGAAATTTTGTCTAAGGAAAAGTATAAAATTTACAATGCAAACAAGTATAAAGGTGATGTGAAGTCGGAAGAACATTGGTTCAATATTGAGGATGCAAAAAGGAAAAATCCTAATTTACCTGTCCATGAATAATACACAATACAAACATTAGGTGAAATAAATATTAACCCCTGATCATGAGAGTGCGAGTAGACACGTCCGGGGGGGGGATTTGTGGAATAGCTTGAGAAAATGGTTATCGAGTATTCCAAACTAAAGTTTACCAAACCTTTAATGGTTTTCACTAAATATTCAAAACTAACATTATGTACTTAACAGATTTTAATAGGTAAATTAAAAACTTTATTTAGAGCTGGAATTAATTCATTAAAATTTGGTTTTACAATAAAATCTTTAGCTCCTAATTCTAAAGCTTCAATAATCACAAATGATTGACCCATTGACGAGCACATGACAATTTTAGCTTCTGAATTTATCTTTATTAATTTCTTTAAAACATCAATTCCATTAATGTCAGGTAAAGTTATATCTAGCAAAACAATATCTGGATTGAATTCTTGGTATAAAGAAATGGCATCATTACCATTTGATGCTTCGGAAATAACTAGGTAATTGCTTTCAGATAACACATTTTTTAGCATGTTTCTCATAAAAGTTGAATCGTCAATAATAAGTACAGTTTTATTCACTTTGATCATTCCCTTCTAATGTTAAGGCAAATTAAGAAAGGGATAATTTGAAAAGTTGTTAAAATAATTTTTTGTAAATTGCAACCCGGCTACCATGGCAAAAAAGTTTGCTTTAGGCCCGTGGCTTTGCGTCCTTTACTTTCGTAAAATTTGCCTATGTAGGTATATTAGCATAATTTGTCGAAAATTATGGTGTTTTGTCATATTAAGATGTATCCAATTAAGAAAACCTCTAAACCAATTGGTAGCAGTTATGCAAATATCTTTACCGATTATAAATGGCGTGGTCCTAAAGGTGCAAAATCAAGGTGGGGTAGCAAAGGTGAATGAAACAATGGAATACAGTATTAAGAAACTAAATGAAGCAGGCCTGTTCCTTCTTTATCGGGATGTTGTTAATAGGATTGGTTCTCATGTAATCGGTGGCTCTCCAGATGTAAATTACATTCAAAATCAGGAAGCCATCCTCAATGTTGTACAAGATGAGCTTCAAAAAAGAAAATAAAAAAGCCAGGATCTCTCCCGGCTAGGTAATATCACGACAATATTATTATAGCATGGGGGAGTTCCTTTGAGACTAAGAGAAATTGACATTAATCATAGTACGATGAAAATAGAGATTGATATAATGGAACTAAAAGGAAGTTTCGCCATTGTTGTTTGTGATGGGAAGGCTAAATTAACGGAGCTGCCAAGTCATGGTGAAACAAAAATTGTTACACATCAGGGAAAGGTTAAACGGGTGAAGTTTGATGAGGGGGAAGATTTTTGAGTCATTGGATTAAAATAAAGAAAATATTATTAGAAATTTTAGTGATAATACTTGCGTTTAGTGCATATGTAGCCTTATTAATATTTTTTAATAATTATCAGTCAATATTTACAAGCTTCTTTAATTTTGTATTTATGAGTTATCTAATTTTGAAAATATTTTCATTAACCTCATGGATATCTGAAAAAAGAGATTTACGTAGGTTAAGGAATTCACAGATTTATCAATCGAATAATAAGGTACTCTATCAATGGTTAGGTAAAGGTGAATATGACTCTAATTTCTTTTTTCAATTCACAGATGATCCAATAACATCCGATCCATTAAGAAACCTCAAGAAAATTAAAAGAAAAATACACTTTAAGATAGGTTCAAATCTAGAAGATTATTATCTACTAAAAAACTATATTGAAGTATATGAAAAAAACAATCTGCTTAGTAATTTTTCTACAATATTTATAGGTATAATTGTTGCTGTAATCACAACTACGATTTCTAGAATAGTAACTACAAATTCAGTTTCAGATAAAATTATGGAAGTTATCTTTAATACTAAAGTCCATGATACATCAGAAAAAATCACCATGCTTTTAGATATATCCACTTTCTGTATAATTGGTATTGCAATAATAATTTATTCTATTAATGAGTTTTCAAAAGAAAAACGCAGACTGGAATTAATAAAGTTGATTATTGGATCAATCATTAGTGATTATGAAAAGAATAAAAAATGATTGTTCTACCAGCTCTCTGGAGGACACTGAATGAACGGTTTTTACCGTCATTTGGTGTCCTTTTTTATTTGACCAATATGAGGTGATGTCATGAATCCAACTTTAAAAGACCAGCTAACGGAATGGAAAAAACAACACCGAGAGTTAACTACAGCTAAGAAAAAAAACGTCGTCAGCAGCCACAGAAGCGCAAATCAGAGCATTTAAGTGAATCGGATATTAAGAGTCTTATGGGAATGGGGATGCCGAGGTATGCACGACACAGAGGGGCATTGAGACAAAAATAAAAAGGAGCTGATCGCGTGAGAGTATTAATGGCTGAATATCGAAAATCACTTCGAGATGCAAGAAAGATGAAAAAAAAATTTGATTCGAGAATCCAAAGTGCATTAGACAAAAAGAAAAAGCCATCTCCTCAAGACATTGATGATAAAAAAGTAATTGCCAGCATAATCAGCGACTTGGAATATGCACTCGAGTGGATGAGGAGTGGAAGAAATCCGGATGCTAGGCGTGGAATTGATAAACGCGGAGTGTATTTAACGGATCCATCAGTACTTGATGTATTACCGGTGCATCCTTTTTATGTTGAACTTTCTCATGCTAGTGAAATTACCCACTATGAAAATGAAATCATTGAAGATGCGTTGTGTACATTAACTGAGAGGGAAAAGGATGTTTTCCTCATGATTAAAGTTGAAGGGATCACTTTTGAATACACTGCAGAAATTCTGGGAGTAAAGAAAAGCACGGTGCAGACACATTTTAAGAGGGCAGAAAAGAAAATTGAACAGAGAAAACATGAGAGCCTTTTTCTAGTTTCTTGAAAAAGGCTTTCTTAATAAGAAAGTATTAACACTAATTTTTCACTTTGTTAGTTTATAAATTGTTTCAGTGAAAACCTCTTTACTTTGATTAAAATCACATTGTTTTAGTTCAATGGTTTCATTATTCAAGAAAGTAAGTGTGAGTGATAAATCACTAAATTTTTCAATACCAATCATATCTCTAGTGTATTGTAATAAGTTTATCTCTTTTTTTTCGATATCTTTGATATTTCTTACATGAATTTTTGCAAAGTTTTTGGTTTTGTCGTTACTATTTAGAACACAGTTTGCTTCAAGTAAATTAATGGAATCAAATACAAAAATGTTAATTTCTATTTGATCGGTATCTACAACTTTTGTTAAATCACCAACCTCTGTTCCTGGTTCAATAATATTGCCCAATGCTGAAACGAATTGTTGTCCGATAGGGAACTGATTTAACCAATCGTAAATTTCTTTATAGCTGTAAACCGCCATAATCAACACTCCTAAAAATAATATATAATAATAGATTTCGGTAAAGAATTTGAAATAACTTCTATCATATTACAATTTTCAAATTTGATTGTGTTTTTTGTCGTACAAATGATGTATATATGGAGAATTATTTTCCTTCAACAACATTCAATATGGTATTGTAGGTCTCAACATATAAGCTGGATATATTTTCAGAAAGATTTTTATTCATTGCTGAACTAGTAGAATTATCCGTGTACTTTAAGTGACCAGCAAATTGAATTGTTATTTCCTTTGCTAATTGTGCTACTTGAAGTCTTTGTTCGTTGCTTAAACTCATTATTACCACCTCCTTTTTTACAATATTCGGTAATATTAGTTAAAATCCTATTATATTATTATTTGTTCACCAATATTTAACAATTAGGATTATAGGAACCTTTCTCCTTTTGTCGAAATGTTAAGTGAGAGGAGTGAAGCAAACATGGAACCAAGAAGAATATACAATGTAGAAAGCCATTATTTAGTCGAAATCGATGATGTTAAGTCATATGGAAGTAGCGGCACTCTAACAAAAACCTATTCATGGGATGTCTACATCGCATCAAAAGGGTCAGAGTATCGCGGAAGAGCAGATGAAAAAAATAAGAATATTTCTATTCCATGGACCGTTCTAAAGGAAAATAATCTTTTAGAAGAAATGATAAGAATCATTGAGTACACAATGATGAAATATTGATTATATTTCGAGTATCCTTCGGGGTGCTTTTTTATTTTCCCAAAACAAACAAATCATATTGGAGGTGGGTGATTGTGTAGATGGCTAGAGCTAGAAGTCCTAACCGAGATAAAGCATTCGAGTTATGGAAGGAAAGCAACGGGACCATTCTCCTTAAAGAAATTGCAAGTCAATTAGGTGTAACTGATTCCCAAATTCGTAAATGGAAAAACCATGATAAATGGGAAGAGTTAATAAAAAGTAACGTTACTAAATCAAAAGGTAACGTTACTAATAAAAAAGGCGCTCCTAAAGGCAATAAGAATGCTCAAGGTCAAGGCGCACCTAAGCAAAATAAAAATGCAATTACGCATGGCTTCTTCTCTAAATACTTACCGCAAGAATCATTAGATATCCTTAAGGAGATCCAGCAGCGTTCCCCGGTTGATATGATCTGGGACCAAATCATGATTCAGTACACAGCTATAATCAGAGCACAGAAGATTATGTTTGTCGAAGACCGAGATGATATTACCAGAGTATTGAAGAAAGAAAAGCCTGGGATGTTTGGTGACGAGCACGAATGGGAGTTTCAATTTGCATGGGACAAACAAGCCTCCTTCCTAAATGCTCAGTCCAGGGCAATGAGTGAACTTAGAGGATTAATTAAGCAGTTTGACGAAATGGCATACATCGATGATGAGCGCAGGCTGAAGCTTGAAGGAATGAGACTAAACGTAGAGAAAACAAAAGCTGAAATCGAGAATATTTCAAACGATGAAGATGATACTTCTTTCGAAATTGTCATAAAGCGAAAAGGTGACAGTTCATGACCATAATTGAAAAAGAAGTTAATCCACACTTTGAGGATTTTCTCTTCGATTGGAATCAAAAGTTTCAGTTTCTTGTTGGAGGATACGGATCTAGTAAAAGCTATCATGTTGCATTGAAGTTGATTCTAAAATTGCTTTCAGAAAAACGAACAGCGCTTGTCGTTCGGGAAGTATATGAAACTCATAAAGATAGTACATTTTCATTGTTTAACGAAATCATTGAAGAACTTGGAGCCTTGGATGATACAGGAAAAAAGAAAATTGCTAAGGGGAAAATAAGACCAAAAGAAAGCCCCTATGAATTAAGGTTTTACAATGGGTCTAAAATCATTTTTAAAGGAATGGACAAGCCAGCAAAACTTAAATCAATTAATAATATTTCAATCATTTGGCTTGAAGAGTGTTCAGAAATTAAATACGCAGGTTTTAAGGAACTTCTTGGTCGTTTACGGCATCCTAAATTAAAATTGCACATGATTCTCTCAACCAATCCTGTTGGTGAAGATAACTGGACCTTCAAACACTTTTTTAAAGATGAGCAAAACAAACGTCTGGTTCTAGATGATAAAGAACTTTATGAAAAGCGTACTGTCATTGTAAAAGATACCTATTACCATCATTCAACGGCCGATGATAATTTATTCCTTCCAGAAAGCTATATTGAGCAGTTGGAGGAAATGAAAGACTATGATCCAGACCTTTACCGTATTGCCCGGAAAGGTCGTTTTGGCGTGAATGGGGTTCGGGTATTTCCTCAGTTTAGGGTTAAGGATCACAGTGAAGTCATGGAGGATATTTCAAATATCAGGACTGTAATTAAGCGAGCTGGGATGGACTTTGGTTTTGTTGAATCCTATAATGCTTTGCTACGTCTAGCCGTGGATCATAATAAACAATACCTGTACATCTACTGGGAATACTACAAAAATCAAATGACTGATGATCAAACGGCAGAGAAAATAATTGAGTTTAAGGAATCACAGGAACGTATTAAAGCAGATAGCGCTGAGCCTAAAACCATTCAATATTATCGGCAAAAGGGCTTTAATATGGTATCTGCGAAAAAATACCAAGGTTCTAGAATTCAGTACACAAAAAAGATTAAACGTTTCAAAAAGATCATTTGTTCAGATCAATGCACGAACACGATTTACGAATTAAAAGACCTTACCTATGCAACAGATAAAAACGGGAGGATCATCGAGGATGAATTTAAAATCGATCCTCATACATTGTCAGCAATTTGGTATGGATTAGATGATTATGAGATTGCCGATCTGAAAGATAAGAGTAAGAAGAGACCAAACAGAGAAAGGAGGTAGGCTATGGGCCAGCAAAAAATGAAAGCTAGAGTCATAAAGGTGGACCAACCATCCACCTCAACTAAGCAGATATATGACGATCCTTTTAAAGATTTATATAGTGGTGAGATCATTGCGCCTCCTTACAATTTAAAAGAACTGAAATTAATCGGTGAATATTCAACCATTATTCAGCAGTGTGTCGAAGCGTATAAAGTCAATATACTCGGGTTTGGATTTATTCCTAAGTATCGGTTTGATTACAATACCGATGATACATCAAATGAATTAAAAACACTTGCTGATAAGGAATGGACCAGGCTTGAAGAATTTGTTCGCTATCTTAACTATGATGAAGAAGCTGAAACGATTTTTGGTTTTGCTCTTGAAGATCGTGAGAAGATGGGCAATGGATATGTGGAAGTGTTACGAGACTCATTAAATATCCCTGCTGGTATTGAATATGCAGATGGACAATACATCAGAGTTTGCATACGTTCAGTACCAGAAGAAGTAGAGTATAAAATCACTATAAATGGTCAGGTAAAAACCATTAAGCGATGGCGCACCTTCAGAAAATATATTCAAGAAATTAATGGGGCTCGAGTCTGGTTTAAAGAATATGGGGATCCACGAATCATGAATCTTTCCACCGGTAAGTATGATGAGAGCACGCCTGAACATTTACGTGCTACCGAATTGATTCATTTTAAAATAGGATCTGGCACCTATGGCATTCCGCGATGGATTGGACATATCGTCAATTTATATGGAACAAGGAAAGCTGATGAACTTAACTATCTATATTTCAAACAAGGTCGACATACACCTGCAGCTATTGTGGTTGAAAATGGGATGCTATCAGATGACTCAGTTGCCCAATTAAAAGAGTATATGTCTGGAATTGAAGGAGTTGACAATGCTCATAAATTTCTTTTGCTTGAAGCTGAAGGGGTAGCAACGGAAGACGTTCACGGTGACGAAAAAGTAACACCAGTTAAGGTCCAGATTAAATCATTAGCTGAAATACTCCAGCAAGATGCATTGTTCCTTGAATACGATTCGAAGAGTAGGGACAAGCTTCGATCAGCATTTCGATTACCGCCTTTATACACTGGGGAATCACAGGATTACAACAAAGCCACAGCTGAGACCGCAAGAAAAGTAACCGAGGAACAGGTATTCCGTACTGAAAGAAAGACCATAGCCGGTAAATTAAACACCTTATTTTTAGGTGATTTAGATATTTTCAATGTTATGTTGACGCTGAATGGTCCTAACTTTGGAGATCCACTAGATACAGCTAAAGTATTAACACCATTTATTAATGCTGGATCAGCCGCACCAAATGATTTACGCGATCTATTGGGCCAGGTATTAGGAAAAGACTTAGAAATGTTCCCTGAAGAATACAATGTTCCTCTCCAAATGATGAGGAATGTACCAGCTCAACCATTATTACCGATCATGATGAGGAAATCAGCCAACAGTGATTTGGTTAATATCCTAAAGGATTTACGTGACGTTATTGAGGAGATGCAATCATGAGTAAGGTGGAGCGTCTCCTTAAGTCTATTAATGCTGTGATAAAGGCCAAGGAAGAGGATGAAGAGATCACTGATGTGGTACCTGACTTCCCCGGTTTAGATAAGATTCCCAAGTACATCGAAGATTATGAGAAGAAGGTAGCTAAACTATTTCGAAATCAGCGAAAACATTTTTTAAATGGAGTCAAAGATTATATTCAAAAGGATATTACCATCGAAGGATTATTAAACTTTCTTTCTCAAGATTTATTTGCTAGCGATGAATTCTTAGCGGATATGGAGGAAACAACAAAAGACTTTCTATTTTTGACTATTACGGAACTTACATCTGAGATCATGGATGCTATCGATAAGGATGTTGCCTTTAGTATCCTTTCGACACGGACTACCGATTGGATTGATTCCTGGTCCCATGATTTAGGTGAAATTATGAAATTGAATACTCATCAGTCGTTAGAAGATGCACTGAAAAAGGTGATTGAAGAAGGTGGATCTATTGCAGATGCTGAACTAGCCATAAAGGATTTGCCGCAGTTTGACCGACTTAGAGCACGGACCACAGCTATTACGGAAATATTAACTGCCTCGAGCCGTAGCCAATGGGAAGCATATATGCAAAGTCCTGCAGTAACTAAGAAAAGTTGGAAACATTCAGGTGGTAAGAAGAACAATCCACGAAAAGAGCATGAAGACTTAGATGGTACTGAAATTGGAGTGGACGAGAAGTTTGACGTAAATGGAAATGAAGCTGATTACCCACGAGATCCTTCTCTGCCAGCAAGCGAGAGGGTGAATTGTCATTGTGCGTTGGGACCCGTCGTTGATCAAGACATTATTGGTCTATCAAAAGAAGAAAAAGAGGTATTGAGACAACAAGTGTTAGATGAAATGAATACCTAAACCAGGTCACCAAATGAGGTGTTTTTTTATCATGGAATGGAGGAAACAAAATGGTAAGAGCTAAATTTGTATGTATTGAAAAAGGCGAGACTGGACATCAACCATGTCAAAAACAAGCAAAGGTAGTATTGCAACCTGTATTCGGTAATTCAGATGAAAACAAAAAGTTTTGGCAATATACTCCTACTGGTCGCATTGAATTATCAACAATAAATACTGATGCTGCAGAACAGTTTGAGGTTGGCAAAGAGTATTATGTTGATTTTACGAAGGCTGAATAATGCTGAAGGGAGGTGAACAAATTGGCAAGAGAACTTAAAAATGCAAATATTACACATGTTTCCTATGTGGATAAGGGAGCCAATCAAAAGCAATTCTTTCTTACTAAAGCAGCAGGATCCCCAACACCTACATTTCAAAAAGAAGTAAAAATCATCATGAAATCTGAGGATGAACAGCAACTTGTATATGGTGTTGTTTACGAACCAGACGTTGCAGATGCTCATGATGACATTATGAATGCTGATGAAATTGAAAAGGCAGCTCATAAGTTCATGAAAGACTTCCGCAATATCGATACTCAACATGATTTCGAACGTGGTGCTGGGGAGTTGGTGGAGTCTTACATCGCGCCTGTAGATATGGATATCGATGGAGAGATAATCACAAAGGGATCCTGGGTAATGGTTACAAAGGCCACTGATGATATATGGGAGTCAATCAAAAAAGGGGAGTTTACCGGATATTCGATGGCCGGAACTGCCGAGACAATTGAAAAGAAAGCATCAAAGCCTGTCGCTAAATCGGATGATGATGTGAAGGGCTTTTTTAATGCCATGAAATCATTCTTTTCTGGTGAAAAAATTCAAAAAGGTGCCGTCCGCGATAAGTACGAGCGCGGAATTAAAAGCCGCAATTTTTGGTCTGCGATGGATAGTTTCGAAACTGTGATTCGTTCTTACAATTGGCAAACCGATAACTATGAATTTGCTGAGGACGAAACAACAGTTCGTGAAGCCATACAGGATTTTACTGAAATCATGAATGAAATCTTACTAAGCAACAACGTATTAAAAGCTATTGGTAAACCGACCGAAGAAATTTTGAAAGCTGGTAAAAAGATTTCTGGGGCACGAATGGACCAAATCAATGCAGCTTATGAGGCACTTAAGGCACTTAAAGAAGAAGTAGATGGGGAGGAAGAAGTCATGAAAGCAGAAGATATTGCAAAAATGTTAGATGAAAAATTATCACCAATAACCAAGCGCTTAGATGCTATTGAAAAGGAAGAAGGTACAGGTGTCACTCCTACAGGTGAAGATGATATTGTTAAACAATTTGGTACGCTTCTTGATGAAAAGTTAACACCGATCAATGACCGTCTTGATGCTGTTGAGAAAGCTCGCGGAGTTTCTAAGCAAGTTCATCAAGAGCCGACTCCTGTTGTAAAGTCTAGCGATGGTCCATCTTACATGCGCCACTTTGAATAATAGTTTTAAAAAAAGAGAGGATGATATAAATGGCAACGAATCAACAAATTATCACAAAAGAAAATCAGCTTTCTACTATCAAGAAAAACATTGATATTCCAATGGCAACTAGTGATGCCCAAGCGTTCTTAATTGATACAATCAACAAGGCAACTACATTACCAAAATTAAACCCAATCTTCCGTGATGTTGCTGCAGGTAATTTAGATGCTTTAAGTGTTGGTCGTCGTAAAATTCGTGAGGCAAGCAAGGATGACGAACCGAACGGAACTGGAGCAATCGGTAAACGTAAAATTCCGTTTGCAGTTAAGAAAGTTAAATGGGATGAATGGTTACAAAACGATGACGTCTTTTACTCTCAGGCGGCCCGTGGTGATGATGTAGAAGCAAAGGTTATCAGCATGATTCAGCAACAGTTTGCCGTGGATCTGCAAGACCTAATCTTTAACGGGGACACAACAGCATTGTTACCAGATGGAGTGACTCCAGATCCTTTCTTATCTGTCATTGACGGGTTCGTAAAGAAATGTAAAACATCACCTTATAAAACTGTTCTTGGGGCAAATGAACCTACTATTTTGGATTTCGTGAACCACATTCAGTTACTTCCAGAACGTTATAAGAGCTTCTCAGATATCTGCTGGAACATTACTCGTAAAACTAATGATAAGTTGGTTGCATTAGTTTCTAACCGTGCTACTGGTTATGGTGATGCAGTTTTACAAGAAGGAAAGATTACTAGAATTGCTGGTTACCCAGTAGAAGTTGTAGCAGAGTTACAAAGTGGGTTTGCTTGCTTATGCCCACAATCTAACTTAAAACCAGTCTTTACTCGTGATTTACGTTACATCCGCACAGGGGTCGGCGCAACTGCAGCTGCTAAAGATGCGACCTACCATGTTCTTTATGCTTACCTTGACGCGGTTGTTCGTGAAGTAGAAGCTTGTGCATGGATGTCTGGAGATAAATTGTAAGGAGGAATTACAATGCCAAAAGTTCAATACAAATCAAAGGAAGGTGCTCTCCACATTGGTGGAGGGCACTTCTTTTATCCAAATGATCCGGTTGAAGTATCTGTCGAGGAAAAAGAGCAACTACTAGCTGACTATGGAGAGTACTTAGAAGAGGTACTTACTCCAGAGTTACACACAAAAGCAACCCTAAAAAAACTGAATAAAGAACAACAAGAAGCCATTATTGCTCAGTTCGATGGAGATCCTGTTACGCCTCGTAATGAAGAAGAACGGATTACATTAATTCTTGATCTACAAGAAAAGAAGGCGGCCGAGTAATGCCTAGGATTACGGCTGCAGATGTAATTGGATATACCGTTTTCGATAAGGTGAAACAAAGACCACCGACATTATTAGAAATGGATATCATCGAGGCAGACCAGGAAATTAAATCAATTGTGGGCCACACATTTAATGGAGTGGATACAGAGGGAAATCCTTTGTATCCAGCATTGCCTCCAGAGGTTGAAATTGCCTATTTAAAAATGGCGCAGTTCTTTGCTTTGATCAATAGCGACGAGTCAATCACAAAAGGTTATCAGAGCGAACGTATTGGAGATTACTCCTATACATTGGCTAATGGACAGACTGTTCGAAAACCCGATGTGTTTGACCTACTATCAGCCTATATTCAAGAAAAAGAAAAAACAACCGGCAATACGAGGATGAAAATGAGGTCGATCTAATGAGTTATCAAGATTTATTGACCGATCGTTGTGCCGTTTATCATCTAGTTGAGAATCAAGAGGCAGGTTCCTTTGGTGTTCCTGGGGAAACTGCCTATTCTTATCCAGTTCTTTCAGATTTGCAAAACGTCTCTTGCTTATTTGCAAAAGAGTCTACAAAAGTAGTGAAAGAAGAGCCAGGAGTTGAAATTGTTCAATCGTTCCGGGTTCATTTTTTAATAAATACAGATGTCCGGTTTAACGACAAGATTGTTTTAAATGGAACCAGCTATCGTCTTGAGATTCCTCGAAATATTAGAGGTCATCATATTGAGGTGACTGCTATAAGGAATGATCTGATTTGAAAACAAGAGTGAAGGTACATGGAATAGAAAAGGTATTAAAAAAGATTGAGAGACTTGCGGATCCGGAATTAAAGAAGCAATTTGCATTATGGCTAGAAGCAACAGGATTTGAATTTTTGGATATTGTCCAAGATGAAATCATTCGCTTGCAAGTCGTTGATTTTCGTAATCTATTGAACTCCTTTAAAAAAGGCGACAAAGATAACGTTTGGGCAATAAAAAATGGAGGATTAACCCTTAATATCGGGACAAATTTATCCTATGCGAAAATCGTAAACGATGGGCACTGGACAGTTAAATCTAGTACACCAGGTGCTTTTGAATTAAAAAACGGAACATTAGCTAGATGGGTTCCGGGAAAATGGAACGGATCACGTTTTGAATACGATCCATCTTCTGATACAGGGATGTTATTAAAACAACAATGGATAGAAGGTCAGCCGTATTGGGATCAAGCCGTAGCCATATTCGAGAAGATATTTGCAGCTTCTTTTGAAAGGAAATTCAGGCAGTGGATTCAAAGTGAGCTAGGGGATGGATAATGTGGAACAAATGCTAGGTTCGATTCGAGGGTATTTTTATTCCCAGTGGCCAGTCAAAGTATATTCAAAAACAATACCAGAAAACATAGAAACAACCAGCATGTACTTCCCTCCTCCCTAGCACATTAGATACCAATTTTAGTAAACAGGATTATGAAGTTGTCTATCTATTGTCGGTAAAAATTTTTCATAAAACGTCCTCAGAAGCTCTTATTCAGGCAGAAAAAATCGCAAATAGTATAAGACAAAATAAACGAACTATTCCTGTTTTAAATCAAGATGGGACTATAACAGAAGATAAAATTATATTTTCAAAGATTGATTGTTCCATTATTGCAGATAACTTAGCTGTTATGAAGATTCAATGGGCGAAAGAGTATCCGTATAGTTAGGACGTGAGTCAATGTTTAAATTTAGAGTTTTAGTACAGTTTTCATATAACAATGATATGTACAATCCTCGGCGACAAACCTATCAACTTGATGATGAAATCGTCAAAGAATGGGAAAGTTCCGGATATGTAAAAATCGTAGAAAAATCTGCGAAAGATGATAAAAAAACAAAGGAGGAATAGATAGATGCGCGGAGTAGACGTAATTATTCAAGTTGAAGGTGCAGTCGCTGGAACATTTATCACTATTGCCAGTCAACGAGGTGCAAAATTCACGGAAGAAGTAGATACAATTGAAACTACTAGCAAATCTTCTAATGGCTGGAAAGAGTATGATTATGCTTTAGCTGGTTGGAAAATTTCCTGTGATGGTGCGTATGTTTTAAATGATGCTGCATACGACAAGTTAAAAACAGCTATGCGGAATAAGACAAAAGTAAAAGCAAAATGGAGTGAAACTGGCTCGAGCGGTGACGTGGAAACTGGGGATGCACTTGTAACAAGCCGAGAATTAGACGCACCTTATGATGCAGAGGTAACATATGCCTTTGAACTATTAGGAACCGGATCACCAACAACCGTTACTAATCCTTAATTTAAAGTCCGTTTTATACGGGATTTTTTATTTTTTTTGAAAGGGGAGTATGTTTCAATTGGCTCAATTAAATGTTCAAAACTTGCCTATAAACGGTTTGGTTAAAACAATGTCTTCAGCATCTGCAGGCGGCGATACTTTTACAAATGACGGAAATACTATCCTTTATGTAAAAAACGGAGGAGCATCACCTGTTACCGTAACCGTTAATTCTGTGGCCCCTTGCAGCCAAGGATTTGATCATGATCTTGTTGTTTCATTAGCAGCCGGTTCCGAAATTTCTTTTCCTAAGCTAGATCCATATCGATTCAATGACCTATCGACAGGACTTGTTTCAGTATCATATAGCACTGTTACATCAGTAACAGTAGCTGCGGTAAGACTTAACTAATTCAGGAGGGTATTTATATGTCTAACTTAAAAACCTATGTAGAAGTTCATTTTGGTGGAAAACAAAGACTATTAAAATATGATGTTAATTCAGCTTGTGACTTAGAGGACCACTTTGGTAAAGGTGTCCCAGCAATTTTAAATGAGGAGCAGATTGGATTCCGTTTATGCCGAGGCTTTTATTGGGCAGGTCTTAAATGGAAGGAGCATGGGCTTACGATTCAGCGTGTAGGATTGATGTTAAACAAAGAAATTCAAGAAGAAGGAAAAACCATCATGGATATGATGGAGCCAGTAATGGATGCGTTGAAAAAATCAAGACTATTAAATGCTCCAAAAGATGAATTTGATGAACAAGACGCGGTTGGCAACGAAGAAGAGCCAGATGAAGATAGTGAAGTTACCCCAAACTAAATAAGGGTTTAAATTGGGTGCTTATTAAGCAAATAGCTTACGGACCTCTTAATTTAAGCCCTGAACAATTAGGTAGATTAACGTACGGCGAATTTTTGGACTTGTACGATGGATATAAGTGGCGAGAAAAAAGGCGATTGGAAATGTTGGCTTTATCCGCTTCGTGGATTACAGCTCCCCACCTTAAGAGGCCAATTGATCCCAATGATTTATTAAAACCTGCTGCTAAAAAGAAAAAAGTTACCCAAGAAGAGAAAGAGCGTGTAACGAGAGAAATTGAAGAGAGATTGGGGGTGAGGTAAGTGACCACAATCGCGGAAATGATGATCGAAATCGGCGCCGATACTTCTGATCTTGATCGCTCAACGAGGCGAATGGAAAATGAAATACGCGGAGTTGGCAGTACAGTAGCAACACTTGCGGATGATATGGGAACAAGTACTGCAAATATGCAGCGACAATGGCGGCAAATGAGCGAACAAATGAAACAGGCAGTTCGGCAAAATAAGGCAGCATTAGCACCATTCAAAGCTCAACAGCAGGAAATCCAATACGAGTTTTTTCAAATGGCTCAAGGTATGGGGGAGTACCAAGGATCCACACAGGAGTTTATGAATGAGCTGACACAATTGGGTAACAGGAACAGACAAGTGAATGACCAAATGATCTCTAATAATAATCTGGCACGGATGGGATTTATTCAAGGAATTGCAACTATGCTAGCCAAAAGTACAGCATCTAGTAAAATAGCTGCTAATTTTAATCGTATGAATAACCCATTATATAGAGTTAATAACGGATTATTAGCTATTAGTGGTGGTATGGAGAGAATGGCGGCAAGAGGACAGCCGGCAGTATTAGCTTTAAGGATGTTGGGACCAACAGCAAGCATGAAAGCACTTAATGATATGACTATGATGATTACGGCGGGGATTATGCGGATGCAAATGGTGGCTATGGGAGCAGCGGTTGTAAGCGGGATTCTATATACTTCTCTAGCGAAAGCAGCGTATGAATCTGTTCCTAGCTTTAAAAAGGCTGCAGATGAAATGAAGGCATCAGTAACAAAAGCATTTGAACCAATGGTCCAAGCTTTTGCAGCTGTGGTTACACCTATTATGAAGGTGATCACGGCCATTGCCAATTTGGCCATAAAATTTAATGAAGCGCACCCATTTTTAGCCAAATTAATCGCTGGATTTTTAATGCTGATACCAATATTAACTTTAATTCTAGCACCATTAGCTATAGGGATCGGATTATTCGGAGGGATGCAGGCGGCTTTTTCAGCACTATGGCCATTAATTGGACCTATTGTAACTGGGCTAGCTTCCATGTTGGGAACAGTAATATTAGTTTCAGCAGCATTAGTAGGTGCAGGGGCCGGAATTGTTTGGCTATGGAAAAATTGTGAGGGATTTAGAAAAGCCATCGAGGCTTCTGTGAATGCGATTAAATTTTTTGGACAAGTGATTCTTGATTTAGGTAAATATTTATTCTGGGCAGCTGTTGGTGGTGACACTGCTAATGACTGGCTAGGTCACCTACCTAAAGGGTTTCAAAACGCAGCAAAACAAATAGGAGATGCAGTAGCTGCAATAAGTAATACTGTTACAAGTTTGGTTAAATATCTATTCTGGGCGGGTGTTGACGGTGACGCTGCCAATGATTGGTTAGGTCATCTACCTAAAGGGTTTCAAAACGCGGCACAAAGTATGGGGGTTTTTGTAGCTGCATTATCAGATTTAGGAAAATACCTCTTTTGGACAGCAGCTGATGGAGATTACGCAAACGATTGGCTAGGACACTTGCCGAAGGGTTTTCAAGAAACAGCACAAAAAATGGGTATTTTTATCTCTGCATTAGAAGATTTAGGTAAATATTTATTCTGGGCAGCTGTTGGTGGTGACGCTGCTAATGACTGGCTAGGTCATTTACCAGAAACATTCCAAGGAGCAGCACAAGCAATTGGGCAGGCTGTAAGTAATATCAGAAGTACCATAATACAATTATTTAATGCCATAAAAGCGGCCTTCAGCGGTGATTTAACACCGCTGACACAAGTGTTTGCTCAATTGGCCCCAACAATCATTTCGTTATTAGTCGGAGGAATTCCTTCGCTTATAATGACTGCAGCTCGGTATTTACCTGCGATTGCTCAAGGACTTAGCAATAATGCCGGCTCTGTTTCCGGAGTCATAAACAACATCATCTCAAATGTTGTTAATCTGTTTACAACAGCTCTTCCGAAATTACTCACAGTAGGATTGCAGATTTTGCAAAATATCATTAATGGAATCACACAAGCTTTACCAGTTATTTTGCCAATATTGATTAATACGATAACGGGATTATTAACGGGAATTCTAGAACAAATCTCTATAACATTACCAATTCTACTAAATGCCGGTATTCAAATATTAATGACTTTGGTAAACGGAATTGTACAGGCATTGCCAAGTATTTTTACTGCAATTATCACAGTAGTTATGACACTTGTAAATGAAATTGTTACCAATTTACCTATAATCCTAAATGCTGGAATTGAAATACTCTTAGCGTTAGTTAATGGAATAACTCAAATGCTTCCACAATTAATCACTTTGGCTCTAAATTTAATTACCCAAGTTGCAAATATGTTGATTCAGAATTTACCGATGATTATAGACGCAGGAATTAAAATTTTATTGTCTCTAATCGATGGAATTATTCAGATTTTGCCGCAATTAATAGATGCAGCTGTTAAATTAATTGTTCAGGTAGCAACAACATTAATTGATCAATTACCTAAAATAATTGACGCTGGGGTAAAATTGCTTCTTGCTTTAATAAATGGGATAGCAAAGATATTACCACAATTGATTATTTGTGCAATTGATCTCATTGTGCAGATAGCGTCGGCATTGATTAGTAATTTACCTAAAATAATCGACGCTGGTGTTAAATTACTAAAGGCATTAATCAGCGGAATCATTCAATTGGCTAGTAGCTTAGGTTCGGCTATAAAAAATGACATCATCCCTCAGATTATCGACAAATTAAAAGAGGTAGATTTATTGCAGATTGGGAAAGACATCATAAATGGGCTTATAAAAGGTATCGGAAGCATGGTTGGCGCAGTCGCAAAAAAAATTGGTGAAGTTGCTGGGAACATTAAAGACACAATTACTGGTGCACTCGGTATTCACTCTCCATCTCGCTGGATGCGTGACATGATTGGTAAAAACATTCCTCTAGGAATGGCTATTGGTATTGAGGCAGAGAGTGGCAGTGTTATAGATTCATTGAATTCACTGGCAAAGGATACTCAGAAATTTGCTACACAATTACTTCAACCACCAGATTTACCATCATTATCAAATCAAGCTTTAAGTCATGAAATTGCTCACCAATCAAGTAATGGCCAGCCTATTTACATTGAAATGGACGGACGAATTGTGGCAAAGGGTATCATGCCTCATGCGGTAAATGAAATCAGGCAAAAGACCGGAATTAAGTTTAATTAA

Protein sequences of DBSCAN-SWA_1

>NC_021171|221385:272511|258325_258580_+|WP_015592085.1|DBSCAN-SWA
MEPRRIYNVESHYLVEIDDVKSYGSSGTLTKTYSWDVYIASKGSEYRGRADEKNKNISIPWTVLKENNLLEEMIRIIEYTMMKY
>NC_021171|221385:272511|221837_222539_+|WP_015592042.1|tRNA|DBSCAN-SWA
MKVLAIDTSNYALGISLIDEDKVIGEYITNVKKNHSVRVMPAIEELMKVCDILPSDLTKIVVAKGPGSYTGVRIGVTIAKTLAWTLNIPLVGVSSLEVLAASVGRYFQGSISPLFDARRGQVYTGLYQFNEGKLQVIKKDQLVLSQDWAQDLKKRSESILFIGNDLPIHRNGIEEVLTHQAYFAEITEHNPRPSELALLGRDLPGEDVHSFVPNYIRLAEAEAKWLEAKKEMQ
>NC_021171|221385:272511|222559_223009_+|WP_015592043.1|DBSCAN-SWA
MNGSLTFRDMELKDIDDVLKIEHESFTAPWSREAFVNELTSNRFAVYIVIEEAEQVVGYCGVWVIVDEAHITNIALLPEHRGKKLGEALLLKVMEVTKKLGAVKMTLEVRVTNSVALALYRKLGFKDGAIRKGYYTDNREDALVMWVEL
>NC_021171|221385:272511|242233_243331_-|WP_015592062.1|DBSCAN-SWA
MYVPIMKNRKEELIVIKNMNGYFNDSMIPLIELIKDEHEKKYEIDENTGKFIYEQKAGKTRRNRIGIPPTEADIITLKAINERLNGKKAFIEFFRFSEGEYDKKKTYKNIELAFRLSRDFAYYRQRMLEIGNYANLIPVISIKSGFKIGPHILIKFINDLKLNNQSIVIRITDYYLEEYAELLETHLRSSDYIMLDIRDKNADSKFLELEEFQELETDAKKILLNSPRSQTHKNGDFENLVFTGKINNQVANIYKEYNLDGFGDFGGLKDALPEEGGSNGKGSALGLIYLKEKNAFFSVVNHDTDKGVRGYEYVRSEILQRLNLLDRENHCLAIKRIKDMGLTFGSWGTWNNLTLTRYIQQQSQE
>NC_021171|221385:272511|255623_255824_+|WP_015592081.1|DBSCAN-SWA
MRLREIDINHSTMKIEIDIMELKGSFAIVVCDGKAKLTELPSHGETKIVTHQGKVKRVKFDEGEDF
>NC_021171|221385:272511|235744_236032_+|WP_015592055.1|DBSCAN-SWA
MLKPIGDRIVIELVESEEKTASGIVLPDNAKEKPQEGKVVAVGTGRVLDSGERVAVEVAVGDRIIFSKYSGTEVKFQGTEYLILRETDILAVVAE
>NC_021171|221385:272511|251355_251595_+|WP_015592074.1|DBSCAN-SWA
MPEICLIGFNGPDPFSIIVWQLDGVDRTKTICYTTKEELNALERFHTAGDFYNRYDKAVVVYQDKQSVEYVKIPEKKGA
>NC_021171|221385:272511|236093_237728_+|WP_015592056.1|DBSCAN-SWA
MAKEIKFSEDARRAMLRGVDALANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGIRKGIEKAVIAAIEELKAISKPIEGKASIAQVAAISSADEEVGQLIAEAMERVGNDGVITIEESKGFTTELDVVEGMQFDRGYASAYMVTNTDKMEAVLENPYILITDKKISSIQEILPVLEQVVQQGKPLLLVAEDVEGEALSTLVVNKLRGTFNAVAVKAPGFGDRRKAMLEDISILTGGEVITEELGRELKSATIASLGRASKVVVTKENTTIVEGAGETAEIAARVNQIRAQLEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVSGGGVALLNVYNKVASIQAEGDEATGVNIVLRAIEEPVRTIAHNAGLEGSVIVERLKREEVGTGFNAANGEWVNMIKAGIVDPTKVTRSALQNAASVAAMFLTTEAVVADKPEPAGAGGGMPDMSGMGGMGGMM
>NC_021171|221385:272511|265616_265922_+|WP_015592093.1|DBSCAN-SWA
MPKVQYKSKEGALHIGGGHFFYPNDPVEVSVEEKEQLLADYGEYLEEVLTPELHTKATLKKLNKEQQEAIIAQFDGDPVTPRNEEERITLILDLQEKKAAE
>NC_021171|221385:272511|240987_241302_-|WP_041580211.1|DBSCAN-SWA
MNIIYTSNKLERILTNQRLIKKEYTAFYKNVINRMSELTAANNLEEISHDPPPCRHKLTGEYEDCWGIAVSKNYRIVLRPVGEWDEQDHKTISDIEILTIEDYH
>NC_021171|221385:272511|266328_266673_+|WP_015592095.1|DBSCAN-SWA
MSYQDLLTDRCAVYHLVENQEAGSFGVPGETAYSYPVLSDLQNVSCLFAKESTKVVKEEPGVEIVQSFRVHFLINTDVRFNDKIVLNGTSYRLEIPRNIRGHHIEVTAIRNDLI
>NC_021171|221385:272511|244630_245161_+|WP_015592066.1|DBSCAN-SWA
MEIGRAAMAAKLARKETGLTQQQMTLDEYFGSRESVSSQENGRYQVQPELGRYYSEKHNDPWVAMEAAAEYTGWGIVKLDGEAADLHRTSVSLKTREELKEALEAVMDASKNLTVNPKCVERVEIAVIEKSLHECIDAITALNHYVAVICKEYGIPWAKMWTQHKIKLIQRRFIKK
>NC_021171|221385:272511|263190_263421_+|WP_015592090.1|DBSCAN-SWA
MVRAKFVCIEKGETGHQPCQKQAKVVLQPVFGNSDENKKFWQYTPTGRIELSTINTDAAEQFEVGKEYYVDFTKAE
>NC_021171|221385:272511|245327_245525_+|WP_041580212.1|DBSCAN-SWA
MFGLTPEQYFLFLSIHINHLKTIGTENQKKYCLSKVRNVEWDSKRKCLNVYYDDTSWKYDDNGWY
>NC_021171|221385:272511|259397_260714_+|WP_144061537.1|terminase|DBSCAN-SWA
MEKEVNPHFEDFLFDWNQKFQFLVGGYGSSKSYHVALKLILKLLSEKRTALVVREVYETHKDSTFSLFNEIIEELGALDDTGKKKIAKGKIRPKESPYELRFYNGSKIIFKGMDKPAKLKSINNISIIWLEECSEIKYAGFKELLGRLRHPKLKLHMILSTNPVGEDNWTFKHFFKDEQNKRLVLDDKELYEKRTVIVKDTYYHHSTADDNLFLPESYIEQLEEMKDYDPDLYRIARKGRFGVNGVRVFPQFRVKDHSEVMEDISNIRTVIKRAGMDFGFVESYNALLRLAVDHNKQYLYIYWEYYKNQMTDDQTAEKIIEFKESQERIKADSAEPKTIQYYRQKGFNMVSAKKYQGSRIQYTKKIKRFKKIICSDQCTNTIYELKDLTYATDKNGRIIEDEFKIDPHTLSAIWYGLDDYEIADLKDKSKKRPNRERR
>NC_021171|221385:272511|254674_255052_-|WP_041580213.1|DBSCAN-SWA
MNKTVLIIDDSTFMRNMLKNVLSESNYLVISEASNGNDAISLYQEFNPDIVLLDITLPDINGIDVLKKLIKINSEAKIVMCSSMGQSFVIIEALELGAKDFIVKPNFNELIPALNKVFNLPIKIC
>NC_021171|221385:272511|232268_232838_+|WP_051120187.1|DBSCAN-SWA
MSPKPEQINNEQKLFKNLSKKQIIFLLLIVLAFVGLGGLAVVKASDNPAFCSTTCHNMKPQYNSYQNSSSNLLAYKHAKAKIVCHDCHQDSLTTKAQEGVKYVTGNYEDPMKTRTFSKEMCLKCHDWKKVQKKTASLGTKANENPHNSEHGGQRECSTCHKVHEQSTNGCLKCHGASWANKLDISWKKK
>NC_021171|221385:272511|250490_251363_+|WP_051120109.1|DBSCAN-SWA
MADLQAKAQNRQSEKPMMPEEHGEVDYNCPICKDTELVLYRENGYEMAKYCECRERNAWKRRFNQSMIPDEFTNANFENFQRKSKTLESMYQLTFDYIRNFKVEKKEDGSTKKVIPSKNFGLIAVFGEQRLKELPPAERSTVKQEHNNFGIGKTHLQIALAKRLIKDGFNVLIVSDVIFIEELMQAKIMKDEGETYNRLLHNTLTADVLIWDDIGKVSWTEPRERMYYTIINERYRKQKPIVFNSNEDRGTLAEKIGYAAASRLIGQAEEFLIEAEGQDWRLKKGANVNA
>NC_021171|221385:272511|267793_268201_+|WP_015592098.1|DBSCAN-SWA
MRGVDVIIQVEGAVAGTFITIASQRGAKFTEEVDTIETTSKSSNGWKEYDYALAGWKISCDGAYVLNDAAYDKLKTAMRNKTKVKAKWSETGSSGDVETGDALVTSRELDAPYDAEVTYAFELLGTGSPTTVTNP
>NC_021171|221385:272511|244009_244255_+|WP_015592064.1|DBSCAN-SWA
MSPKDLQQLLINKREYLGLTQQDVAEQSDAEITRQYYGMIENGERRPSVDVAKKISNVLGVEWTIFFEINSNQKLLNKNTA
>NC_021171|221385:272511|253725_253893_-|WP_187292136.1|DBSCAN-SWA
MTYHNKIRSILGVDVRARYSETDSGNYEPFKNPLIHKQINGSEIVPLNITKLWRN
>NC_021171|221385:272511|233568_234321_+|WP_015592052.1|DBSCAN-SWA
MIDKELLLVDHLEELRKRIILSALAFLFSFVVGFFYAIDIYKWFVKDLDVKLLVLGPSDIIRIYFMLAAVVAIAGTMPFLATQIWLFVRSALRAKERKITLTYIPALFILFIVGLAFGYFVILPMIFKFLIQLGGAMLVTNFTAERYFKFIMNMTIPFGVLFELPVVIMFLTSLGMINPFVLSRIRKYAYFVLIIIAVVITPPDFMSDFVVTIPLLLLYEISITLSKFVYRKKLKGEKNMKDLDLDCLME
>NC_021171|221385:272511|223005_224028_+|WP_015592044.1|tRNA|DBSCAN-SWA
MRKDLLIMGIESSCDETAVAIVKNGREIVSNVIASQIESHKRFGGVVPEIASRHHVEQITIVLEEAMKQAGVTFKDLDAIAVTEGPGLVGALLIGVNAAKAIAFAHSIPLVGVHHITGHIYANRLVTEMNFPLLSLVVSGGHTELVYMKEHGDFKVIGETRDDAAGEAYDKVARTLNQPYPGGPHIDRMAQEGKPTINLPRAWLEEGSYDFSFSGLKSAVINTVHNAEQRGESIKPEDLAASFQQSVIDVLVTKAVKAAKEYQVKQVLLAGGVAANKGLRAALTEAFTKIPEIELVIPPLSLCTDNAAMIAAVGSVLFEKGKRANLSLNGNPGLDITIYN
>NC_021171|221385:272511|243494_243845_-|WP_015592063.1|DBSCAN-SWA
MFADRLKKLRLNKKLSQQYMADLLGITRQGYGKYENEEKNSSQPDFSTLKKLAEFFGVSIDYLVTGNENGNSSDEMWRELLDPKKQVFFKDLMDAPEEKIEELIRFWEFIKERDKK
>NC_021171|221385:272511|257989_258181_-|WP_041580215.1|DBSCAN-SWA
MSLSNEQRLQVAQLAKEITIQFAGHLKYTDNSTSSAMNKNLSENISSLYVETYNTILNVVEGK
>NC_021171|221385:272511|263442_264630_+|WP_015592091.1|terminase|DBSCAN-SWA
MARELKNANITHVSYVDKGANQKQFFLTKAAGSPTPTFQKEVKIIMKSEDEQQLVYGVVYEPDVADAHDDIMNADEIEKAAHKFMKDFRNIDTQHDFERGAGELVESYIAPVDMDIDGEIITKGSWVMVTKATDDIWESIKKGEFTGYSMAGTAETIEKKASKPVAKSDDDVKGFFNAMKSFFSGEKIQKGAVRDKYERGIKSRNFWSAMDSFETVIRSYNWQTDNYEFAEDETTVREAIQDFTEIMNEILLSNNVLKAIGKPTEEILKAGKKISGARMDQINAAYEALKALKEEVDGEEEVMKAEDIAKMLDEKLSPITKRLDAIEKEEGTGVTPTGEDDIVKQFGTLLDEKLTPINDRLDAVEKARGVSKQVHQEPTPVVKSSDGPSYMRHFE
>NC_021171|221385:272511|245775_245970_+|WP_015592068.1|DBSCAN-SWA
MFDTKKGPVYEPDHPALNGMYELLKKDAATLSGSRLYEDLVDVYESINMDLKEEMDNGKTIKAS
>NC_021171|221385:272511|268609_269005_+|WP_015592099.1|DBSCAN-SWA
MSNLKTYVEVHFGGKQRLLKYDVNSACDLEDHFGKGVPAILNEEQIGFRLCRGFYWAGLKWKEHGLTIQRVGLMLNKEIQEEGKTIMDMMEPVMDALKKSRLLNAPKDEFDEQDAVGNEEEPDEDSEVTPN
>NC_021171|221385:272511|237808_239029_-|WP_015592057.1|integrase|DBSCAN-SWA
MAYFRKIDSNNKQGYKWVCVKDGPPDPVTGKRNQIPRRGDTKKEAEAKVDEAIRKLTDHGIDDKKIKNLPFEKVALEWLNTYSRGKVKASTVRVREKEIKILLRYIAKVNIDKVSPRMHQNILNDLDDKEYAKTTIEGVHVTANMIFNFAIKEKMRRDNPCTGSVIPVKKLTVEDIENNTIEEKYLEKDELSEFLSTAHQYGLLMDMEIFYLLAFSGMRSGELCALKWTDVDFETNEIRITKTLYNPDNNMHKYELTPPKTKGSIRTFDIDDSIIDLLKAHKKNQAKIKMANRHKYPDYHDKNFIFCRENGYPFIQKNIIIRMNRLLKKTSIQKNATPHIFRHSHISMLAEAGIDINTIMKRVGHDDMKTTMKIYTHITDKMKKNATEKIKNHFGSILNLAKSQEM
>NC_021171|221385:272511|245157_245340_+|WP_015592067.1|DBSCAN-SWA
MKKDITHRIAYYVRKVNERMSFHPSKKLPAKYTYRHERLMAYKKRMFELIEEGEYKKCSD
>NC_021171|221385:272511|249613_250567_+|WP_015592072.1|DBSCAN-SWA
MADVQLENGYIRIATELIDEVIRRDFSKRQLAILHFIIRLSYGCHKKDCVIEKFNSFELAGLNKSDIKKELKFLRDCRVINWDEETMIFSINKDYEKWQINPSKGFDKEKLSQLIHINIKRKVGKTPTDLENVVGKTLTDLGEVVGKTLTSKLVKYQLEMNGNAWESMDEDTLKDSIIDIYLKINKEEEEKALMNRILELLQKSKILEEKDITEFLREDINDVINNFDFEQPEEMIIEAIKDAARGNGRTWKYVYKKLVDWKKKGIKTTADIEEKSGKDGENGAKVYQHRPGYGRSSSKSAEQAIREADDARRAWGG
>NC_021171|221385:272511|248888_249590_+|WP_015592071.1|DBSCAN-SWA
MIEITALASSSKGNCYRVTDGHTPLLLECGINYREVQKGFDFRLSEVAGCLVSHEHGDHCKAVKDVLKAGIDCYMSAGTAQGIGVNHHRIKKVEAKKQFMLGSWTILPFDVQHDVSEPLGFLLVNQSGEKLLFATDTYYIKYRFQGLTHVMCECNYSREILIQNIINGSVPKVMKKRLERSHFSLEDVKDFLLSNDLKKVQEIWLLHLSDSNSNADQFKREIQELTGKMVLVP
>NC_021171|221385:272511|241421_242228_+|WP_015592061.1|DBSCAN-SWA
MQKNDYFEFAKLLSNQYFTFLSNETIKREVLKTFNGQLPYDQNNSDLTPREFLNQFILHYYPNETSVKSTFINNVLFKTSNHVSIFELNVGKSRLDLCKINGCSTAYEIKTDLDTPIRLKQQMIDYFQVFEKVYLICSVQNHDSMVPYIPEECGIYTYYKTNTGKYVFKKKRNAVSSTSISPQAQLSVLTKKDLNTFFQCPNLETKDAMIDVITSSKTNKEINKIFKFILKTKYYDKWNFLVENSDEILEIDYQWFFKNLLSPEIVYL
>NC_021171|221385:272511|233156_233402_+|WP_015592051.1|DBSCAN-SWA
MLSNIGIPGLVLIFILALIVFGPKKLPELGRAVGQTLSEFKKSARDLTSDIVKEIDEAKQDATVQVLTSDVVKKVDEVKKM
>NC_021171|221385:272511|260717_262241_+|WP_015592088.1|portal|DBSCAN-SWA
MGQQKMKARVIKVDQPSTSTKQIYDDPFKDLYSGEIIAPPYNLKELKLIGEYSTIIQQCVEAYKVNILGFGFIPKYRFDYNTDDTSNELKTLADKEWTRLEEFVRYLNYDEEAETIFGFALEDREKMGNGYVEVLRDSLNIPAGIEYADGQYIRVCIRSVPEEVEYKITINGQVKTIKRWRTFRKYIQEINGARVWFKEYGDPRIMNLSTGKYDESTPEHLRATELIHFKIGSGTYGIPRWIGHIVNLYGTRKADELNYLYFKQGRHTPAAIVVENGMLSDDSVAQLKEYMSGIEGVDNAHKFLLLEAEGVATEDVHGDEKVTPVKVQIKSLAEILQQDALFLEYDSKSRDKLRSAFRLPPLYTGESQDYNKATAETARKVTEEQVFRTERKTIAGKLNTLFLGDLDIFNVMLTLNGPNFGDPLDTAKVLTPFINAGSAAPNDLRDLLGQVLGKDLEMFPEEYNVPLQMMRNVPAQPLLPIMMRKSANSDLVNILKDLRDVIEEMQS
>NC_021171|221385:272511|244267_244576_+|WP_015592065.1|DBSCAN-SWA
MFTLQYDDQFIEKIAAKIADRATEMLVERIGSFNDLPLVLTREEAMKVLRCGPTKMAELMARPDFPVSREFGVKIPTHMLTKWIEKNTRWMEANTGYFNKAI
>NC_021171|221385:272511|267618_267789_+|WP_187292138.1|DBSCAN-SWA
MFKFRVLVQFSYNNDMYNPRRQTYQLDDEIVKEWESSGYVKIVEKSAKDDKKTKEE
>NC_021171|221385:272511|239901_240972_-|WP_015592059.1|DBSCAN-SWA
MGENFIVHTGAIIKEYLDELGMSQKDCSKRLGISEKHLSNLLNGKTKLTEDIAIKFEKIFHNVPASYWLNYESKYREYLKREEINQKEFKEKELIELDKRFKFSTVFAGLDWDLKKQANEMLKLLGISNYSLFDDVYSNLSVDFMEDGGEKESIAIWLNLAREEVEIQNRDLSNKKYDRTNLINSLEKFKRIALNNDYQSSLQSARKLLNRLGIYLVFCDAVVNSKVRGALTTYKKNPAIYLSGRFKTHDHVWFALMHEIGHLIMHYEPNIPIITFESELELDNKISTKEDEANEFARDFFIDKKDYKKFTELGIFNQKSIEEFSLSQNILPGIVVARLQHDGYIGFEAFYYLKNK
>NC_021171|221385:272511|258660_259392_+|WP_015592086.1|DBSCAN-SWA
MARARSPNRDKAFELWKESNGTILLKEIASQLGVTDSQIRKWKNHDKWEELIKSNVTKSKGNVTNKKGAPKGNKNAQGQGAPKQNKNAITHGFFSKYLPQESLDILKEIQQRSPVDMIWDQIMIQYTAIIRAQKIMFVEDRDDITRVLKKEKPGMFGDEHEWEFQFAWDKQASFLNAQSRAMSELRGLIKQFDEMAYIDDERRLKLEGMRLNVEKTKAEIENISNDEDDTSFEIVIKRKGDSS
>NC_021171|221385:272511|257424_257862_-|WP_015592084.1|DBSCAN-SWA
MAVYSYKEIYDWLNQFPIGQQFVSALGNIIEPGTEVGDLTKVVDTDQIEINIFVFDSINLLEANCVLNSNDKTKNFAKIHVRNIKDIEKKEINLLQYTRDMIGIEKFSDLSLTLTFLNNETIELKQCDFNQSKEVFTETIYKLTK
>NC_021171|221385:272511|256860_257385_+|WP_041580214.1|DBSCAN-SWA
MRVLMAEYRKSLRDARKMKKKFDSRIQSALDKKKKPSPQDIDDKKVIASIISDLEYALEWMRSGRNPDARRGIDKRGVYLTDPSVLDVLPVHPFYVELSHASEITHYENEIIEDALCTLTEREKDVFLMIKVEGITFEYTAEILGVKKSTVQTHFKRAEKKIEQRKHESLFLVS
>NC_021171|221385:272511|255305_255557_+|WP_015592080.1|DBSCAN-SWA
MQISLPIINGVVLKVQNQGGVAKVNETMEYSIKKLNEAGLFLLYRDVVNRIGSHVIGGSPDVNYIQNQEAILNVVQDELQKRK
>NC_021171|221385:272511|264659_265604_+|WP_015592092.1|capsid|DBSCAN-SWA
MATNQQIITKENQLSTIKKNIDIPMATSDAQAFLIDTINKATTLPKLNPIFRDVAAGNLDALSVGRRKIREASKDDEPNGTGAIGKRKIPFAVKKVKWDEWLQNDDVFYSQAARGDDVEAKVISMIQQQFAVDLQDLIFNGDTTALLPDGVTPDPFLSVIDGFVKKCKTSPYKTVLGANEPTILDFVNHIQLLPERYKSFSDICWNITRKTNDKLVALVSNRATGYGDAVLQEGKITRIAGYPVEVVAELQSGFACLCPQSNLKPVFTRDLRYIRTGVGATAAAKDATYHVLYAYLDAVVREVEACAWMSGDKL
>NC_021171|221385:272511|226999_227494_+|WP_015592046.1|DBSCAN-SWA
MGEFTHFNEEGRAKMVDVSSKPETIRTALAYSSITVSCDIYEKITNNEMKKGDVLAVAQVAAVMACKKTWDIIPMCHPIPLNGVDISFSWGKENNDYILHISAKVKTKGNTGVEMEALTAASVCALTVYDMCKAVDKGMVIGKTFLVEKTGGKSGDFHRENRVK
>NC_021171|221385:272511|227519_228173_+|WP_015592047.1|DBSCAN-SWA
MANEGSSKIPQATAKRLPLYYRFLKNLHTSGKQRVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVNYLLTFFRKTLDQDELTKVALIGVGNLGTALLNYNFLKNNNTKIAIAFDVDPAKVGTSILDVPVAHMDDLEKKIKEENIHVAILTIPAPVAQATTDRLTSGPIKGILNFTPARLNVPSDIRVHHIDLAVELQSLVYFLKHYPKVEEE
>NC_021171|221385:272511|252181_252325_+|WP_187292135.1|DBSCAN-SWA
MICPICNRPLKSLKSIAIGIGPVCVRKLENLNDNADGNQLEMELKEK
>NC_021171|221385:272511|255820_256558_+|WP_015592082.1|DBSCAN-SWA
MSHWIKIKKILLEILVIILAFSAYVALLIFFNNYQSIFTSFFNFVFMSYLILKIFSLTSWISEKRDLRRLRNSQIYQSNNKVLYQWLGKGEYDSNFFFQFTDDPITSDPLRNLKKIKRKIHFKIGSNLEDYYLLKNYIEVYEKNNLLSNFSTIFIGIIVAVITTTISRIVTTNSVSDKIMEVIFNTKVHDTSEKITMLLDISTFCIIGIAIIIYSINEFSKEKRRLELIKLIIGSIISDYEKNKK
>NC_021171|221385:272511|224929_226855_-|WP_015592045.1|DBSCAN-SWA
MILLQVNQLNKYYGADLILSNIKLEVQTRDRIALVGRNGAGKSTLLKIIAGQMSFDSGEIMKPKEVTIGYLAQNTGLESSLSIWEEMLTVFAGLRILEQKLRQYEEQMSDPAILKETSTYEKLLKDYDLLQVQFKDLGGYQYEADIRSVLHGLNFHTFDYSTKISSLSGGQKTRLALGKLLLTKPDILILDEPTNHLDIETLSWLEQYLQNYEGAILIVSHDRYFLDKVVNQVYEMSRQQILKFTGNYSSYLVHKAENYEREMKMYEKQQDEITKLQDFVARNLARASTTKRAQSRRKQLNRMDVMNRPLGNEKSATFSFDIEKQSGNEVLNVHSVAVGYGEERVSENISIRITRGESIALVGPNGIGKSTLLKTIVQKLDPLAGTFQLGSNVSIGYYDQEQAELTSNKRVLNELWDEYPLKPEKEVRTVLGNFLFSGDDVLKIVSTLSGGEKARLALAKLMMEKANLLILDEPTNHLDLDSKEVLENALIDYPGTILFVSHDRYFINRIVTKVIELGKNGAVEYLGDYDYYVEKKLEQVELKALENTPKVGTTLAGTPVKNTYQQDKETKKLERQRQRRMEEIEASVEKLETLISTNEQLLCDPEIYQNHEKVLELNGQNEAAHSTLEELMEEWAELAED
>NC_021171|221385:272511|234719_235451_-|WP_015592054.1|protease|DBSCAN-SWA
MKKKYWIVLITYITMQLSSYIGVPLTVYIGTLFGKTMAEMKVLAVPFWLVISFAITLLIILLVLRNDSDTRFEKNRASITSLVIWAIFGVFLALFAQSVAANIEAMLGIKTGSENTQHIIGIIESFPIVIFISSIVGPILEEIVFRKIIFGALHQRFNFFISALISSVIFALAHLEFEHVLLYSAIGFSFAFLYVKTKRIIVPIIAHVTMNTLVVIIQTVYREDIERMLHQVEKIQSFIGGFL
>NC_021171|221385:272511|252533_253016_+|WP_144061535.1|DBSCAN-SWA
MSSASKYGNRKVTIDSHKFDSVAESKYYMQLKWLEANKQILFFRLQPRYLLQEAFDKGGQHFRKIEYVSDFEVHHLDGSIEVIDVKGVETEAFKIKRKLFEKKYPHKLSLITYKKEFGGWIELEKLKKLERKVVKPHGKKKTTKVGAPVSERRRESGLPI
>NC_021171|221385:272511|251837_252185_+|WP_015592076.1|DBSCAN-SWA
MKLGQQVRFKKFLSKAKDGVSYGWLSEEIEKELEDNCLLRVKKMAEKECNEYKNGIVVGKRKIGIETILEEALDIDGDPVDRFCWRETIYDTVFLVACDLKGLYRVREIDLEEIT
>NC_021171|221385:272511|230472_232197_+|WP_015592049.1|DBSCAN-SWA
MSENEKKGLSRRNFVKGTAIAALGVASAGLLAGCSEKADTARASAETSSEDWLGKAPEISDSKIKQTLKADVVIVGAGVAGMHAARAASEAGASVIVVEKADTFQVRSGQYGIIDSKIQKSLGVKMDKNAAITENMKQMGYRADHRMWNYWANHSGEDFDWLMELAPDHVVLPEDALSLDVNKINISMQHFPVPEGYNPAEEYNPSYPTVMAILPSQKKLMERVHQKCLKQGCKFMFKTWAKTLIRPNNKGRIEGVICQDIKGNYIKIIGKKGVVLATGDYGNNKDMIKYFVPWAVNFFNVYPSVDANGNPANTGDGHKLGVWVGAKMEDGPHAPMTHTLGGPLGVDAFFLANTVGKRFINEDAGGQQLSNALYRQPGNFAWQIFDDKWPEQIGLMNVSHGSVNHCVAADKVPHLKDSSWALGRVSITSREEVRATDGIVIANSLEELVGKLGLDSKAQARLLASIKRYNELCGKGVDEDFGKMAKRLFPIANPPFYAGKMAGGAMLVNMGGLTCDPETGNVLDKDYKGIEGLYAVGNVSGGRFVGDYPTVTAGTSHAFALTYGRLVGMTVAKL
>NC_021171|221385:272511|269022_269307_+|WP_015592100.1|DBSCAN-SWA
MLIKQIAYGPLNLSPEQLGRLTYGEFLDLYDGYKWREKRRLEMLALSASWITAPHLKRPIDPNDLLKPAAKKKKVTQEEKERVTREIEERLGVR
>NC_021171|221385:272511|262237_263140_+|WP_015592089.1|DBSCAN-SWA
MSKVERLLKSINAVIKAKEEDEEITDVVPDFPGLDKIPKYIEDYEKKVAKLFRNQRKHFLNGVKDYIQKDITIEGLLNFLSQDLFASDEFLADMEETTKDFLFLTITELTSEIMDAIDKDVAFSILSTRTTDWIDSWSHDLGEIMKLNTHQSLEDALKKVIEEGGSIADAELAIKDLPQFDRLRARTTAITEILTASSRSQWEAYMQSPAVTKKSWKHSGGKKNNPRKEHEDLDGTEIGVDEKFDVNGNEADYPRDPSLPASERVNCHCALGPVVDQDIIGLSKEEKEVLRQQVLDEMNT
>NC_021171|221385:272511|239044_239695_-|WP_015592058.1|DBSCAN-SWA
MDYQTTLLEDWIEDFYFKLEIYHPHQLDLLDISFRMGLSLIFKDISSRFYHKEVIIDERLSSQEQWQEFGHELCHALRHNGNQLIMSESFIELQEHQANNFMYHFCIPTFMLMNIEFPRTKGQTINLIADTFNVTIDFAKKRLEMFENRVTGELFHREYIKMLEDIPVVHEEPGIIYLDDDIDEYTKFERFINQLDWPDDEKQEVLQGYKEKHEIL
>NC_021171|221385:272511|228810_230262_+|WP_187292133.1|DBSCAN-SWA
MYICKDFILQDPAQFCSSINLVCLCDLEIPTELTSCDMLNLILIKKPVSVNTLYARIQNIILTSSDEGYIPQKLLDAACSGNLQTIADTACSLLGNPIIIYDLGFQILAFSQNLRPENEIYKMAGQDEQMIQQTMAAFFQVKALDTMREKGSSYFWKCYGHDKPLPEDTILIHAPIMLDKVIIGYAVVMKGYVDWDESDLILTDKICKIISLEMKNNYFNKNIKGMLHEHFLRDMLENSIEKREFIEARISTLNLKLNKNIYMAVIQSVNPTHLNSQLHPILKELGKIFKNSIFAVYTDHIVLIHHNNENQELTGQEQERLNTYLNACDMAAGFSMCFHDPCQIKRHYQQAKDALDIGLSLQKPGKVFFFQQLSIYRLFELGNKTTDITDYLHPAVFCLVNYDKENHTEFMKTLYYYIINLKALLKTKEILYIHRNTLVYRINKIQEITNIDLHDGETFFQLYISFKGLEFIAHRTNNKISFF
>NC_021171|221385:272511|234519_234723_-|WP_015592053.1|DBSCAN-SWA
MRQSPLFSGIVHILIACLFTYFAVDSVNTDGWDIFGFILVFLATFDFGSGIRLIGLHIKLRKITQKK
>NC_021171|221385:272511|251597_251825_+|WP_015592075.1|DBSCAN-SWA
MGILLESVKSRKKIKRGAPLEKKMQYVLDELKSMNVNISRTGKPVESLDYDELKEEWVFATILSFDVESPENKFF
>NC_021171|221385:272511|245944_247930_+|WP_015592069.1|DBSCAN-SWA
MVKQLRLLSLELNKFKGVPSFLLDARGENAKVYGDNATGKTTLFDAFMWLLFDKDSQNKKDFSIKTLVDGKEVHMMQHEVEGVFLLNGRKLTLKKVFAEKWTKKRGSITQEFTGHTTDYFVDGVPSKLKEYKTLVDSIVNENIFKLLTSPSYFNEQVKWQDKRKTLLEICGDISDEEVIASESSLSKLPAILQGKSIENHRKIIAARRTEINKEIEKIPVRIDEIKRNLPELDGLDKSELETGINQMNDEIDGKMTQIISIKNGNAITERQKAIQEIEMELLNIKRDHDSDSKDLVYQKKARIQEEQSNISLLKSKLNQVKNNKRYNDENIKNIENQLVQLRQEWTEVNNQEFSHADKCECPACGQSLPEQQVQEARDKALAQFNLSKAKKLEGISEKGKQGSERKQEFIQNNEKLTVEYDKLNGQISDKQTALEKLQEQLNQLEGNIIDINENPVYVAKLKEKSQINAEISDLRSMSDQAIQDIQSEIISLKLKREELQKDAGKFALADQSNNRIEELKQQERKLSAEFEKLEQELYLTEEFIRTKVNLLESKINSRFKYARFNLFKTNINGGLEEVCETAFNGVPYSSGLNNAAKINIGLDIINTLSEHYGFTAPIFIDNSEAVTKLIDTKSQTISLVVSEADKVLRVEHEGNIVREAV
>NC_021171|221385:272511|265921_266329_+|WP_015592094.1|DBSCAN-SWA
MPRITAADVIGYTVFDKVKQRPPTLLEMDIIEADQEIKSIVGHTFNGVDTEGNPLYPALPPEVEIAYLKMAQFFALINSDESITKGYQSERIGDYSYTLANGQTVRKPDVFDLLSAYIQEKEKTTGNTRMKMRSI
>NC_021171|221385:272511|245543_245696_+|WP_187292134.1|DBSCAN-SWA
MSFVLSVSKLMKASEVRELCKEMREQKHILAKQEAIVKALLFSRNKKAAS
>NC_021171|221385:272511|266681_267215_+|WP_041580833.1|DBSCAN-SWA
MKVHGIEKVLKKIERLADPELKKQFALWLEATGFEFLDIVQDEIIRLQVVDFRNLLNSFKKGDKDNVWAIKNGGLTLNIGTNLSYAKIVNDGHWTVKSSTPGAFELKNGTLARWVPGKWNGSRFEYDPSSDTGMLLKQQWIEGQPYWDQAVAIFEKIFAASFERKFRQWIQSELGDG
>NC_021171|221385:272511|254321_254495_+|WP_187292137.1|DBSCAN-SWA
MKSGWIINYKNGNSEILSKEKYKIYNANKYKGDVKSEEHWFNIEDAKRKNPNLPVHE
>NC_021171|221385:272511|221385_221838_+|WP_015592041.1|tRNA|DBSCAN-SWA
MSEFEFISNNPQQTTEFAKQLAQKLQPGDVIALEGDLGAGKTTFTKGLAEGLGISRTVNSPTFTIIKEYQGRIPLYHMDVYRVEDSFEDLGFDEYFEGNGVTVVEWAHLIKDQLPDSILTIYLYHENEYARKIVLKPRGTRYEELCKEIN
>NC_021171|221385:272511|269307_272511_+|WP_015592101.1|DBSCAN-SWA
MTTIAEMMIEIGADTSDLDRSTRRMENEIRGVGSTVATLADDMGTSTANMQRQWRQMSEQMKQAVRQNKAALAPFKAQQQEIQYEFFQMAQGMGEYQGSTQEFMNELTQLGNRNRQVNDQMISNNNLARMGFIQGIATMLAKSTASSKIAANFNRMNNPLYRVNNGLLAISGGMERMAARGQPAVLALRMLGPTASMKALNDMTMMITAGIMRMQMVAMGAAVVSGILYTSLAKAAYESVPSFKKAADEMKASVTKAFEPMVQAFAAVVTPIMKVITAIANLAIKFNEAHPFLAKLIAGFLMLIPILTLILAPLAIGIGLFGGMQAAFSALWPLIGPIVTGLASMLGTVILVSAALVGAGAGIVWLWKNCEGFRKAIEASVNAIKFFGQVILDLGKYLFWAAVGGDTANDWLGHLPKGFQNAAKQIGDAVAAISNTVTSLVKYLFWAGVDGDAANDWLGHLPKGFQNAAQSMGVFVAALSDLGKYLFWTAADGDYANDWLGHLPKGFQETAQKMGIFISALEDLGKYLFWAAVGGDAANDWLGHLPETFQGAAQAIGQAVSNIRSTIIQLFNAIKAAFSGDLTPLTQVFAQLAPTIISLLVGGIPSLIMTAARYLPAIAQGLSNNAGSVSGVINNIISNVVNLFTTALPKLLTVGLQILQNIINGITQALPVILPILINTITGLLTGILEQISITLPILLNAGIQILMTLVNGIVQALPSIFTAIITVVMTLVNEIVTNLPIILNAGIEILLALVNGITQMLPQLITLALNLITQVANMLIQNLPMIIDAGIKILLSLIDGIIQILPQLIDAAVKLIVQVATTLIDQLPKIIDAGVKLLLALINGIAKILPQLIICAIDLIVQIASALISNLPKIIDAGVKLLKALISGIIQLASSLGSAIKNDIIPQIIDKLKEVDLLQIGKDIINGLIKGIGSMVGAVAKKIGEVAGNIKDTITGALGIHSPSRWMRDMIGKNIPLGMAIGIEAESGSVIDSLNSLAKDTQKFATQLLQPPDLPSLSNQALSHEIAHQSSNGQPIYIEMDGRIVAKGIMPHAVNEIRQKTGIKFN
>NC_021171|221385:272511|268259_268592_+|WP_041580834.1|DBSCAN-SWA
MAQLNVQNLPINGLVKTMSSASAGGDTFTNDGNTILYVKNGGASPVTVTVNSVAPCSQGFDHDLVVSLAAGSEISFPKLDPYRFNDLSTGLVSVSYSTVTSVTVAAVRLN
>NC_021171|221385:272511|247929_248889_+|WP_015592070.1|DBSCAN-SWA
MSTQNELAVKTSSERFLNNIQAQFAAEAGSPVAFSDYEKALAQHLFLKLDSVLQDFEAKRINSGKTQQAPYNWHNINMRKLSLDAVHTVQLGLDALIANHIHPVPYFNGKEKKYDLDLRVGYIGKAYYRMEAAVEKPKDVVIELVYSTDHFKPMKKSFSNSIESYEFEIQKPFDRGEIVGGFGYLVYDDPAKNKLILVSEADFDKSRKAAKGDTFWSKHPAEMRFKTLVHRVTEKLQIDPKKVNASYLYVENKESEDEVRKEISENANKDVIDVEFSETPDEPVNKEPKVENHSEHFEEAPPQQEQMEFAPTGTGGPGF

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015592041.1|221385_221838_+|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_015592042.1|221837_222539_+|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_015592043.1|222559_223009_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_015592044.1|223005_224028_+|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.2e-67	41.8
WP_015592045.1|224929_226855_-	ABC-F type ribosomal protection protein	A0A2K9L3Z8	Tupanvirus	7.8e-60	33.0
225635:225653	attL	NA	NA	NA	NA
WP_015592046.1|226999_227494_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_015592047.1|227519_228173_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_187292133.1|228810_230262_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015592049.1|230472_232197_+	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	9.9e-22	25.3
WP_051120187.1|232268_232838_+	cytochrome c3 family protein	NA	NA	NA	NA
WP_015592051.1|233156_233402_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_015592052.1|233568_234321_+	twin-arginine translocase subunit TatC	NA	NA	NA	NA
WP_015592053.1|234519_234723_-	YdiK family protein	NA	NA	NA	NA
WP_015592054.1|234719_235451_-|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_015592055.1|235744_236032_+	co-chaperone GroES	A0A221S4G8	uncultured_virus	5.5e-18	51.6
WP_015592056.1|236093_237728_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.3e-156	58.2
WP_015592057.1|237808_239029_-|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	2.2e-76	42.9
WP_015592058.1|239044_239695_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	4.1e-29	43.8
WP_015592059.1|239901_240972_-	HigA family addiction module antidote protein	NA	NA	NA	NA
WP_041580211.1|240987_241302_-	plasmid maintenance system killer protein	NA	NA	NA	NA
WP_015592061.1|241421_242228_+	sce7726 family protein	NA	NA	NA	NA
WP_015592062.1|242233_243331_-	hypothetical protein	NA	NA	NA	NA
WP_015592063.1|243494_243845_-	helix-turn-helix transcriptional regulator	O64078	Bacillus_phage	1.9e-12	45.3
WP_015592064.1|244009_244255_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015592065.1|244267_244576_+	hypothetical protein	A0A2H4JDL0	uncultured_Caudovirales_phage	4.5e-10	45.3
WP_015592066.1|244630_245161_+	hypothetical protein	NA	NA	NA	NA
WP_015592067.1|245157_245340_+	hypothetical protein	NA	NA	NA	NA
WP_041580212.1|245327_245525_+	hypothetical protein	NA	NA	NA	NA
WP_187292134.1|245543_245696_+	hypothetical protein	NA	NA	NA	NA
WP_015592068.1|245775_245970_+	hypothetical protein	NA	NA	NA	NA
WP_015592069.1|245944_247930_+	AAA family ATPase	A0A1L2K2K3	Aeribacillus_phage	3.0e-216	59.3
WP_015592070.1|247929_248889_+	recombinase RecT	NA	NA	NA	NA
WP_015592071.1|248888_249590_+	MBL fold metallo-hydrolase	A0A1L2JY21	Aeribacillus_phage	5.7e-101	73.8
WP_015592072.1|249613_250567_+	replication protein	W8EKA2	Geobacillus_phage	7.1e-62	50.5
WP_051120109.1|250490_251363_+	ATP-binding protein	S6B1M2	Thermus_phage	6.8e-104	65.7
WP_015592074.1|251355_251595_+	hypothetical protein	NA	NA	NA	NA
WP_015592075.1|251597_251825_+	hypothetical protein	NA	NA	NA	NA
WP_015592076.1|251837_252185_+	hypothetical protein	NA	NA	NA	NA
WP_187292135.1|252181_252325_+	hypothetical protein	NA	NA	NA	NA
WP_144061535.1|252533_253016_+	DUF1064 domain-containing protein	A0A2P1JTY5	Anoxybacillus_phage	1.1e-50	74.0
WP_187292136.1|253725_253893_-	hypothetical protein	NA	NA	NA	NA
WP_187292137.1|254321_254495_+	hypothetical protein	NA	NA	NA	NA
WP_041580213.1|254674_255052_-	response regulator	Q56AR1	Bacillus_thuringiensis_phage	2.0e-07	31.5
WP_015592080.1|255305_255557_+	hypothetical protein	NA	NA	NA	NA
WP_015592081.1|255623_255824_+	XtrA/YqaO family protein	A0A1L2JY31	Aeribacillus_phage	4.5e-19	69.7
WP_015592082.1|255820_256558_+	hypothetical protein	NA	NA	NA	NA
WP_041580214.1|256860_257385_+	sigma-70 family RNA polymerase sigma factor	A0A0S2MVE1	Bacillus_phage	2.8e-20	37.2
WP_015592084.1|257424_257862_-	hypothetical protein	NA	NA	NA	NA
WP_041580215.1|257989_258181_-	hypothetical protein	NA	NA	NA	NA
WP_015592085.1|258325_258580_+	hypothetical protein	NA	NA	NA	NA
WP_015592086.1|258660_259392_+	hypothetical protein	A0A1L2JY44	Aeribacillus_phage	4.0e-73	64.7
WP_144061537.1|259397_260714_+|terminase	PBSX family phage terminase large subunit	A0A2P1JTW5	Anoxybacillus_phage	4.9e-146	60.6
WP_015592088.1|260717_262241_+|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	9.0e-144	51.1
WP_015592089.1|262237_263140_+	hypothetical protein	A0A249XXB6	Clostridium_phage	6.1e-47	39.5
WP_015592090.1|263190_263421_+	hypothetical protein	A0A2H4J182	uncultured_Caudovirales_phage	3.2e-05	41.7
WP_015592091.1|263442_264630_+|terminase	terminase	A0A1B1P7E4	Bacillus_phage	3.3e-85	54.2
WP_015592092.1|264659_265604_+|capsid	phage major capsid protein	NA	NA	NA	NA
WP_015592093.1|265616_265922_+	hypothetical protein	A0A1B1P7E2	Bacillus_phage	3.3e-05	46.6
WP_015592094.1|265921_266329_+	DUF3199 family protein	A0A1B1P7D6	Bacillus_phage	6.3e-20	45.2
WP_015592095.1|266328_266673_+	YqbH/XkdH family protein	NA	NA	NA	NA
WP_041580833.1|266681_267215_+	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	4.0e-46	52.4
WP_187292138.1|267618_267789_+	hypothetical protein	NA	NA	NA	NA
WP_015592098.1|267793_268201_+	antigen A	A0A0K1LLF6	Bacillus_phage	2.1e-31	52.3
WP_041580834.1|268259_268592_+	hypothetical protein	NA	NA	NA	NA
WP_015592099.1|268609_269005_+	hypothetical protein	W8EEV4	Geobacillus_phage	1.5e-37	63.4
268672:268690	attR	NA	NA	NA	NA
WP_015592100.1|269022_269307_+	hypothetical protein	A0A0K1LMC7	Bacillus_phage	3.7e-19	65.6
WP_015592101.1|269307_272511_+	phage protein	W8EBC4	Geobacillus_phage	7.4e-63	54.0

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_021171|346610:356572|DBSCAN-SWA
CATGATTGAACGTTATACTCGCCCTGAAATGGGTGCGATTTGGACAGAAGAGAACAGGTTTCAGGCATGGTTGGAAGTTGAGATTTTAGCTTGTGAGGCGTGGGCTGAGCTTGGTGATATTCCAAAAGAAGATGTGAAAAAGTTACGAGAAAATGCAACTTTTGATATTAACAGAATTAAAGAAATTGAAGAACAAACAAGACATGATGTTGTTGCGTTTACTCGTGCAGTATCTGAGACCTTAGGTGAAGAACGTAAATGGGTTCATTACGGATTGACCTCCACGGATGTCGTTGATACAGCTTTGTCTTACCTTATTAGACAAGCAAATCAAATTTTATTTAAAGATATTGAAAATTTTGTTGAGATTTTAAAAAATAAAGCAGTAGAGCATAAATATACGGTTATGATGGGCCGTACTCATGGGGTACATGCTGAACCAACAACCTTTGGTTTAAAGCTTGCTCTTTGGTATGAAGAAATGAAGAGAAATCTTGAGAGGTTCAAACAGGCAGCAAATGGAATTGAATTTGGTAAGATTTCTGGGGCGGTTGGTACATATGCAAACATCGACCCATTTGTGGAAAAATATGTTTGTGAAAATTTAGGCTTACAGGCGGCACCAAATTCAACACAAACTCTTCAACGCGACCGCCATGCTCATTATATGTCAACATTGGCTCTAATCGCGACATCTATTGAAAAATTTGCCGTGGAAGTTAGAGGATTGCAAAAGAGCGAAACTCGAGAGGTTGAGGAATTTTTCGCAAAAGGTCAAAAAGGTTCTTCGGCTATGCCGCATAAACGTAATCCAATTGGTTCTGAAAACATGGCCGGATTAGCGAGAGTAATTCGGGGCTATATGTTGACAGCTTATGAGAATGTACCACTTTGGCATGAACGGGATATTTCCCATTCTTCTGCTGAACGAATTATTATTCCAGATGCAACGATTGCATTAAATTATATGCTCAATCGCTTTGGCAATATTATTAAAAACTTAACGGTTTTCCCAGAAAATATGAAGCGAAATATGGGCAGAACTTTTGGTCTTATTTACTCTCAACGCGTTCTACTTGCACTAATTGACAAAGGACTTTCCCGTGAAGAGGCATATGATACGGTTCAGCCGAGAACGGCGGAAGCTTGGGATAAGCAAGTACAGTTCCGTGACCTAATCGAAGCCGATGAAAAAATTACGGCTCATCTTTCCAGTGCTGAAATCGCTGATTGTTTTGATTACAGCTACCATTTACAGCATGTGGATACCATTTTTGATCGTCTTGGGCTATAAATAATCATATTTAATACAAGGTAAAGGTTCATCCTTTACCTTTTTACACCCCACTTGTACTGAACATTCCTAATATTTGCATTAGCTGAAGGGAGAGAAGGGCACATTCTTCCGTCTTGATCCTAAGTCGCAGAATCCGCCCGAATTAGATGAAAGAACTACTTTATGAAGGTAAGGCAAAGAGAATTTATAGTACTGATGATGAGAATATTGTTTTAGTAGAATATAAGGATTCTGCTACAGCATTTAATGGGGAAAAGAAGGCAAATATCACAGGTAAAGGCCGTTTGAATAACGAAATTACTAGTTTGCTATTTCTAAAGCTTCATGAACAGGGTATCGAGACTCACTTTATCAAACAGCTTTCTGAAACAGAGCAGCTTGTTAAAAAAGTAAGCATTATTCCATTAGAGGTTGTTACTCGAAATGTAGCAGCTGGAAGTCTTGCCAAACGATTAGGAATGGACGAAGGTCAAGCATTATCAAAGCCAATCGTGGAGTTTTATTATAAGGATGACGATTTAGGGGATCCTCTCGTTAACGTGGATCATGTTCTAGAACTTAAGATTGCTACAGTTGATGAACTTGAAACATTAAAAGAAAAGGCACTAAATATTAATGCGATTTTATCAAGCTTTTTTGCAGAATTAGGAATTCGTTTAATTGATTTTAAATTAGAATTTGGGAAAGATCATACCGGAAAAATTGTGTTAGCGGATGAAATTTCCCCTGATACTTGTAGATTATGGGATGCAAAAACAAATGAAAAGCTCGATAAGGATGTATTTCGTCGTGATTTAGGTAATCTTACTGATGCTTATGAAAATATTTTGGCTAGACTAGGGGGCCCTCAGCATGGTTAAAGTTAAAGTTTTTGTCACATTAAGAGAAAGTGTTTTAGATCCACAAGGAAAGGCAGTAAATCATGCCTTACATTCTTTAGGATATGAAGAAATCAAAGACGTGCGCATTGGTAAATATATGGAACTTTTCGTTGATACTACAGGCCGTGATGTAGATACAGTTGTAAAAGAAGCTTGTGATAAGCTGTTAGCTAATCCGGTTATTGAGGATTTCCGCTATGAAATAGAGGAGAGTGTCTCCCAATGAAATTTGCGGTAATCGTTTTTCCTGGTTCGAATTGTGACGTTGATATGTATTCTGCGATTAAAGATGAACTAGGATCTGATGTTGAATACGTTTGGCATGCAGAGAAAGATTTAGATCGTTTTGACGCGATTCTTTTACCAGGTGGATTTTCTTATGGAGATTATTTAAGATGTGGTGCGATTGCCCGTTTCAGTAATATCATGAATGAAATTAAGAAAGCGGCTGAAGCAGGAAAACCAGTTTTGGGTGTTTGTAATGGATTTCAAATTTTACTTGAAGCAGGACTATTGCCAGGTGCATTAAGACGGAATGAAAGTCTTAAATTCATTTGTAGACCAGTTGATCTTAAAGTTGAAAACAATAATACGTTATTTTCAAATGAATACGAACAAGGCGAAATCATTTCTGTTCCCGTAGCACATGGTGAAGGAAACTATTATTGTGACGAAGAAACGTTGAAAAAGATGCAAGAAAATAACCAAATCGTCTTTACTTATGTAGACAATCCAAATGGAAGTCTTGAAAATATTGCTGGTATCATAAATGAGCGCGGAAATGTATTAGGAATGATGCCACATCCTGAAAGAGCGGTCGATGAGCTTCTTGGAGGAGCAGATGGTCTTAAGGTATTTAAATCGATCGTAAAACAATGGAGGGAATCATATGTCGTTAAAGCTTGAACCAACTCCCGAGCAAATTAAATCTGAAAGAATTTATGCTGGAATGGGTATGTCCGATAAAGAATTTGCTATGGTTGAAAAAATTCTCGGCCGTACGCCTAATTACACAGAAACAGGACTATTTTCAGTAATGTGGTCTGAGCACTGCAGTTATAAAACTTCAAAGCCTGTTTTAAGAAAGTTCCCGATTACTGGTGAAAAGGTACTTCAAGGACCAGGAGAGGGCGCTGGAATTGTTGATATCGGTGATAATCAAGCAGTTGTTTTTAAAATAGAAAGTCATAACCACCCATCGGCAATCGAGCCTTATCAAGGAGCTGCCACAGGTGTTGGCGGTATTATCCGTGATGTCTTTTCAATGGGCGCTAGACCGATTGCGATGTTGAACTCTTTACGATTTGGAGAACTTTCAGACTCTGCTCGTGTTCGTTACCTATTTAAGGAAGTAGTTGCCGGTATTGCTGGGTATGGAAACTGCATGGGAATCCCAACCGTAGGCGGTGAGGTTCAATTCGACCCTTCCTATGATGGCAATCCATTAGTGAATGCAATGTGTGTTGGTTTAATCGACCATAAGGATATTAAGAAAGGTCAAGCCCATGGGGTTGGAAATACAGTCATGTATGTTGGGGCCAAAACAGGTCGTGATGGAATCCATGGTGCAACATTCGCTTCTGAAGAGTTGACTGATGCTTCAAGTGAAGATCGCCCAGCAGTTCAAGTGGGAGACCCATTTATGGAGAAGCTGTTATTAGAAGCATGTTTAGAATTAATTCATTGTGATGCACTTGTTGGTATACAAGATATGGGAGCAGCTGGATTAACAAGTTCAAGTTCTGAAATGGCAAGTAAAGCCGGATCAGGAATGGAATTGAATCTAGATTTTGTTCCACAGCGTGAAACTGGAATGACTCCATATGAAATGATGCTTTCTGAATCTCAAGAGCGGATGCTCATTGTTGTGCAAAAAGGCAGGGAGCAAGAAATCGTTGATATTTTCTCAAAATATGATCTTGAAGCAGTGTCTGTTGGTGTAGTAACGGATGATAAAATGTACCGCTTGATTCATCAAGGGAAAGTTGTAGCCAATGTGCCTGTAGATGCATTAGCAGAGGATGCACCTGTATATCAAATGCCATCTGCTGAACCACAGTCTTTCCGTGATAATCAAGCTATGGAAAATGAAGTACCTGAGGTAGAGAATTATGGTGAAACTTTGCTTCAATTATTACAACAGCCTACTATCGCTTCTAAGGAATGGATTTATGATCAATATGATTATATGGTTCGGACAAACACAGTTGTAGCACCAGGCTCTGATGCAGCAGTTCTTCGTATAAGAGGAACCGAAAAAGCGTTAGCAATGACAACTGACTGTAATTCTCGCTACCTATATTTAGATCCAGAAACAGGCGGAAAAATTGCCGTAGCTGAAGCAGCTAGAAACATCATTTGCTCAGGTGCGGAACCACTTGCTGTTACAGATAACCTGAATTTTGGTAATCCAGAAAAACCAGAAATCTTTTGGCAAATTGAGAAATCAGCAGATGGGATTTCTGAAGCTTGTCGCAAGCTAAATACGCCAGTAATCGGCGGAAATGTATCTATGTACAACGAAACAAATGGAGAAGCTATCTACCCAACACCTGTTATCGGAATGGTGGGGTTAGTTACTAATCTTAAACATATAACTACTCAATCCTTTAAGGAAGCCGGGGACATTGTTTATCTATTAGGTGAAACAAAGGATGAATTTGGCGGTAGTGAGCTTCAAAAAATGCAAAACGGAAAAATTTACGGAAAATCTCCGTCTATAGATTTAGCAGTTGAAAGTGAATATCAACAAAACGTGTTAGCTGCCATTCGCGCAGGTTTAGTTGCGTCAGCGCATGACTTAGCAGAAGGCGGGCTTGCTGTAGCGATAGCTGAAAGTGCAATTGGTTCTAATGGACTTGGAGCGGATATTAAGGTTTCAGGAAATCCAGTTTCAGCACTATTCAGTGAATCACAATCTCGTTTCTTATTGACCGTTAAAAAAGAAAACCAACAAGAATTCGAAAAATTAGTAGGTGCAACTTTAATTGGTGAAGTTACAGCTGAACCAGTTTTAAATATTACTCAAGATAGTGTAACTATTATTTCAGAGCAAGTTGAAAGTTTAGAAAAGGCTTGGAAAGGAGCTATTCCATGCTTGCTGAATTAAAGGGCCTAAATGAAGAGTGCGGAATCTTCGGCGTTTGGGGACATCAAGATGCAGCTAGCATTACCTATTATGCCCTCCATAGCCTTCAGCATCGAGGTCAGGAAGGGACAGGAATCGTTGTCACTGATGGAACAAAATTGGATATCTTCAAAGGTGAGGGTCTTGTCACAGAAGTTTTTACCTCGGAGGTAATGTCTAAGTTATCCGGCAAGTCCGCGATCGGTCATGTTCGTTATGCAACCGCAGGAGGCAGTGGTTATGAAAATGTTCAGCCGCTGTTGTTCAATTCGGAATCCGGTAGTTTGGCTCTTGCTCATAATGGGAATTTGGTGAACGCAAAATTAATTAAATCAATTCTTGAGCAGCAAGGAAGCATTTTTCAAACTAGCTCAGATACTGAGGTACTAGCTCATTTAATTCGTCGCAGCGGGGAACGTAGAATTAAAGAACAAGTAAAAAGTGCCTTGAAACAGATTGAAGGGGCATTTGCCTACGTAATCATGACGGAAAACGAAATGATGGTAGCTCTTGACCCGCATGGTCTTAGACCGCTTTCGTTAGCACGGTTAGGAGATGCCTATATGGTCGCTTCCGAAACCTGTGCATTTGATGTAGTTGGCGCAGAATTTATTCGTGATGTATTACCTGGTGAATTGTTAATTATCAATGATGAGGGAATTAAATCAGAATTCTTTTCTGAAAACAAACCAAGTGCAATTTGCGCGATGGAATATATTTATTTTTCCAGACCAGATAGTAATATTCATGGGATCAATGTTCATTCTGCTAGAAAAAGACTTGGGAAAAAACTGGCTATAGAAGCACCAATTGTTGCAGATGTGGTAACTGGTGTCCCAGATTCAAGTATTTCTGCAGCAATCGGTTATGCGGAAGCGTCTGGAATTCCGTATGAAATGGGCTTAGTGAAAAATCGTTATGTTGGTCGTACGTTTATACAGCCTTCGCAATCATTAAGGGAGCAAGGCGTGAAAATGAAGCTTTCCCCTGTCCGTGGTGTTGTTGAGGGGAAACGAGTGATCATGGTTGATGATTCGATTGTACGTGGTACGACGAGTCGGAGAATTGTCACAATGTTAAAAGATGCAGGGGCACTTGAGGTTCATGTAGTGATTAGTTCTCCACCGATTAAGAATCCTTGTTTTTATGGAATTGACACTTCTACTAAAGAAGAGCTTATTGCCTCCTCTAATTCTGTTGAGGAAATACGAGAGCTTATTGGTGCTGATTCACTGACCTTTATTAGTACAGAAGGAATGCTAGAAGCAATTGGCAGAATCGACACTGACAAAAATTGTGGTCAATGTGTTGCGTGTTTCACCGGTGAATATCCAACAGAGCTTTATCCAGAATCACTGCAATATTACTATCAAAAATAAGCGGCAGACAATGTCGCTTTTCCCTTTGGAAAGACGAAATGCAAAAAGCGTTCCTAGGCGCTGATGCTAGACACTTTCTACTTTCATAGTTTTTAACTTTTTTTAAACAAAGGAGATTTGGAAATGGCGAATGCTTATAGAGAAGCTGGTGTCAATATCGAAGCGGGATATCAAGCGGTCGAGAGAATGAAGTCGCATGTTAAAAGGACGGAAAGATTAGGTGTCATGGGTGGCCTTGGTGGCTTTGGAGCGATGTTTGATCTCTCAGCACTAAACCTTAAGGAACCGGTATTAGTTTCCGGAACAGATGGTGTCGGAACGAAGCTGATTCTTGCATTTATGGCTAACCGCCATGACACTATAGGAATTGACGCAGTAGCAATGTGTGTAAATGACATTGTTGTTCAAGGAGCAGAGCCACTATATTTCCTTGACTATATCGGCTGTGGTCAAGCAGACCCGTCAAGAATTGAAGAGATTGTAAAAGGGGTAGCAGATGGTTGCGAACAAGCGGGATGTGCCTTAATCGGTGGTGAAACTGCAGAGATGCCAGGTATGTACGATCAAGAAGAATATGATATTGCTGGCTTTGCTGTTGGAGCTTGTGAGAAAGCAAACTTGATTACCGGTAAGACCATTCAAGCTGGAGATGTTCTAATCGGATTAGCATCAAGCGGAATTCACAGTAATGGATTTTCTCTTGTGAGAAAAGTGTTTCTTGAAAAAGCAAAATTATCATTGGACGAATATGTTGAAGAACTTGGTTGTACGTTGGGAGAAGAATTATTAAAGCCAACTAGAATCTATGTTAAGTCTATTTTATCCGCACTGAAAGAATTCCCAATTAAAGGGATGGCTCACATTACTGGCGGAGGATTTCATGAGAACATGCCAAGAATCTTTCCTGAAGGATTGGGAGCTGAAGTAAAGCTAGGAAGTTGGAATATTCCAGCTGTATTTTCACTACTCGAAAAGCTGGGCGAAGTGAAGCATGAAGAAATGTACAATATTTTTAATATGGGTATCGGGATGACTGTTGTAGTGGATAAACAACATGCTACGGCACTTGTTGAACATTTGCAAGGCTGTGGAGAGACCGCTTCTGTTATTGGGGTCGTAACTGAAAGCGAAGGAATTTCGATCATTTAGGGGGATATGAATGAAAAACATCGCCGTCTTTGCCTCCGGAAACGGAAGCAATTTTCAAGCGATTCTGGATGCCGTTACAAATCAAAAGTTGGATGCGGACATCAAGCTACTTGTTTGTGATCAGCCTGGAGCCTATGTGTTAGATAGAGCTAGAGCGGCAGGAATTAATATATTTGAATTTAGTAGTAAGGATTTTGCCAATAAACAAGCGTATGAACAGGAAATTTTAGCTAGATTAAAAGAATGTGAGGTCGAGTTAGTCGTTCTTGCCGGTTATATGAGAATAATTGGAACGACCTTACTTTCCCAGTTTGAAGGTCAAATCGTAAATATTCATCCTTCTTTACTACCATCTTTTCCAGGAAAGGATGCCATTGGACAGGCGTTAGCTGCCAGGGTGAAGGTTAGTGGAGTGACGGTTCATTTCGTTGACGAGGGGATGGATACTGGACCGATTATTGCACAAGAGACAGTCGAACTTGACGGCACTGAATCAGCTGAAACATATCAAGAGAAGATTCATCAAGTCGAGCATCAACTCTATCCAGCAGTTCTACAAATGTTATTGTCTAGTTCAAGGAGGAATGTAAAATGACAAAAAAACGTGCGCTTATCAGCGTTTCTGATAAACAGGGTATAGCGGAATTTGCCAAAGGGTTAAGTGATTTAGGTTTTGAACTTATTTCAACTGGAGGAACAAAGAAGGCTCTTCAAGAGGCGGGAATTCCCGTGATCGGCGTTAACGATGTTACCGGATTTCCAGAGATTTTAGAAGGTCGTGTTAAAACTTTAAACCCCTTGATTCATGGAGGTTTATTAGGGAAGTTTGATCAAGAGGATCACAAAAGACAGATGGAAGAGCATGGTATTTCTCCGATTGAGCTAGTTATCGTAAACTTATATCCTTTTCAACAGACTATTGCAAAACCAGATGTAACTGTTGATGATGCAATCGAAAATATCGATATTGGTGGTCCAACGATGCTTCGTTCTGCGGCCAAAAACCATGAGTATGTAACTGTTGTGGTAGATCCGGCTGATTATCCACTGGTTCTTACTGAACTTAATTTGGCTGGTCAGGTTCAGCCTGGAACACGACGCAAGTTGGCTGCAAAGGTGTTCCGTCACACAGCTTCCTATGATGCAGTGATTGCGGAATATATGACTGAATTATCTGGTGAGGAGAATCCAGAAACATTAACAGTGACATATGAGCTTAAGCAGTCTCTTCGTTATGGAGAAAATCCACATCAAGAAGCGGCATTTTACAAAAAGCCACTTGGATCAAATTTTTCAATTGCAAATGCAACACAATTACATGGGAAAGAATTATCTTATAACAATATAAATGATGCCAATGCAGCATTACAAATTGTCAAAGAATTTACTGAGCCTGCCGCTGTAGCAGTAAAACATATGAATCCTTGTGGTGTTGGAATTGGGGATAATGTTTTTGATGCGTTTACAAGGGCGTTTGAATCGGATCCTATTTCAATTTTTGGCGGAATCATTGCTCTTAATCGGGAAGTGGACAAAGCCACTGCCGAAAAGCTTTATGAAATCTTTTTAGAAATTATTATTGCACCATCGTTTTCAGCTGAAGCCATTACTGTGTTGACGGGGAAAAAGAATCTCCGTCTCCTAACGATACCATTTGGAGAAAAACAAAAAGCAGAACGAAATCTTACTTCAATAGAGGGGGGATTACTTGTTCAGGACCAAGACAGCTATACACTTGAGAATGCAACAATCACGATCCCAACAAAAAGGCAGCCAACTGAAAGTGAGTGGGAATCTTTAAAACTCGGCTGGAAGGTTGTAAAGCATGTTAAATCAAATGCGATTGTTGTGACTAATAAAGATCAAACACTTGGGGTTGGCGCAGGTCAAATGAATCGTGTTGGATCAGCAAAAATTGCCCTTGAACAAGCGGGAGAAAAAGCTAAAGGAGCAGCTCTTGCGTCAGATGCTTTCTTCCCAATGGATGATACTGTTGAAGCTGCCGCAAAAGCTGGGATTACAGCGATTATTCAAACTGGTGGTTCGGTTCGTGATCAAGATTCAATTAAGAAAGCTGATGAGTACGGAATTGCCATGGTATTTACAGGCATCCGCCATTTTAAACATTAA

Protein sequences of DBSCAN-SWA_2

>NC_021171|346610:356572|349009_349693_+|WP_015592162.1|DBSCAN-SWA
MKFAVIVFPGSNCDVDMYSAIKDELGSDVEYVWHAEKDLDRFDAILLPGGFSYGDYLRCGAIARFSNIMNEIKKAAEAGKPVLGVCNGFQILLEAGLLPGALRRNESLKFICRPVDLKVENNNTLFSNEYEQGEIISVPVAHGEGNYYCDEETLKKMQENNQIVFTYVDNPNGSLENIAGIINERGNVLGMMPHPERAVDELLGGADGLKVFKSIVKQWRESYVVKA
>NC_021171|346610:356572|355033_356572_+|WP_015592167.1|DBSCAN-SWA
MTKKRALISVSDKQGIAEFAKGLSDLGFELISTGGTKKALQEAGIPVIGVNDVTGFPEILEGRVKTLNPLIHGGLLGKFDQEDHKRQMEEHGISPIELVIVNLYPFQQTIAKPDVTVDDAIENIDIGGPTMLRSAAKNHEYVTVVVDPADYPLVLTELNLAGQVQPGTRRKLAAKVFRHTASYDAVIAEYMTELSGEENPETLTVTYELKQSLRYGENPHQEAAFYKKPLGSNFSIANATQLHGKELSYNNINDANAALQIVKEFTEPAAVAVKHMNPCGVGIGDNVFDAFTRAFESDPISIFGGIIALNREVDKATAEKLYEIFLEIIIAPSFSAEAITVLTGKKNLRLLTIPFGEKQKAERNLTSIEGGLLVQDQDSYTLENATITIPTKRQPTESEWESLKLGWKVVKHVKSNAIVVTNKDQTLGVGAGQMNRVGSAKIALEQAGEKAKGAALASDAFFPMDDTVEAAAKAGITAIIQTGGSVRDQDSIKKADEYGIAMVFTGIRHFKH
>NC_021171|346610:356572|353416_354442_+|WP_015592165.1|DBSCAN-SWA
MANAYREAGVNIEAGYQAVERMKSHVKRTERLGVMGGLGGFGAMFDLSALNLKEPVLVSGTDGVGTKLILAFMANRHDTIGIDAVAMCVNDIVVQGAEPLYFLDYIGCGQADPSRIEEIVKGVADGCEQAGCALIGGETAEMPGMYDQEEYDIAGFAVGACEKANLITGKTIQAGDVLIGLASSGIHSNGFSLVRKVFLEKAKLSLDEYVEELGCTLGEELLKPTRIYVKSILSALKEFPIKGMAHITGGGFHENMPRIFPEGLGAEVKLGSWNIPAVFSLLEKLGEVKHEEMYNIFNMGIGMTVVVDKQHATALVEHLQGCGETASVIGVVTESEGISII
>NC_021171|346610:356572|348758_349013_+|WP_015592161.1|DBSCAN-SWA
MVKVKVFVTLRESVLDPQGKAVNHALHSLGYEEIKDVRIGKYMELFVDTTGRDVDTVVKEACDKLLANPVIEDFRYEIEESVSQ
>NC_021171|346610:356572|346610_347903_+|WP_015592159.1|DBSCAN-SWA
MIERYTRPEMGAIWTEENRFQAWLEVEILACEAWAELGDIPKEDVKKLRENATFDINRIKEIEEQTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTALSYLIRQANQILFKDIENFVEILKNKAVEHKYTVMMGRTHGVHAEPTTFGLKLALWYEEMKRNLERFKQAANGIEFGKISGAVGTYANIDPFVEKYVCENLGLQAAPNSTQTLQRDRHAHYMSTLALIATSIEKFAVEVRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSENMAGLARVIRGYMLTAYENVPLWHERDISHSSAERIIIPDATIALNYMLNRFGNIIKNLTVFPENMKRNMGRTFGLIYSQRVLLALIDKGLSREEAYDTVQPRTAEAWDKQVQFRDLIEADEKITAHLSSAEIADCFDYSYHLQHVDTIFDRLGL
>NC_021171|346610:356572|348052_348766_+|WP_015592160.1|DBSCAN-SWA
MKELLYEGKAKRIYSTDDENIVLVEYKDSATAFNGEKKANITGKGRLNNEITSLLFLKLHEQGIETHFIKQLSETEQLVKKVSIIPLEVVTRNVAAGSLAKRLGMDEGQALSKPIVEFYYKDDDLGDPLVNVDHVLELKIATVDELETLKEKALNINAILSSFFAELGIRLIDFKLEFGKDHTGKIVLADEISPDTCRLWDAKTNEKLDKDVFRRDLGNLTDAYENILARLGGPQHG
>NC_021171|346610:356572|354452_355037_+|WP_015592166.1|DBSCAN-SWA
MKNIAVFASGNGSNFQAILDAVTNQKLDADIKLLVCDQPGAYVLDRARAAGINIFEFSSKDFANKQAYEQEILARLKECEVELVVLAGYMRIIGTTLLSQFEGQIVNIHPSLLPSFPGKDAIGQALAARVKVSGVTVHFVDEGMDTGPIIAQETVELDGTESAETYQEKIHQVEHQLYPAVLQMLLSSSRRNVK
>NC_021171|346610:356572|349676_351896_+|WP_015592163.1|DBSCAN-SWA
MSLKLEPTPEQIKSERIYAGMGMSDKEFAMVEKILGRTPNYTETGLFSVMWSEHCSYKTSKPVLRKFPITGEKVLQGPGEGAGIVDIGDNQAVVFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFGELSDSARVRYLFKEVVAGIAGYGNCMGIPTVGGEVQFDPSYDGNPLVNAMCVGLIDHKDIKKGQAHGVGNTVMYVGAKTGRDGIHGATFASEELTDASSEDRPAVQVGDPFMEKLLLEACLELIHCDALVGIQDMGAAGLTSSSSEMASKAGSGMELNLDFVPQRETGMTPYEMMLSESQERMLIVVQKGREQEIVDIFSKYDLEAVSVGVVTDDKMYRLIHQGKVVANVPVDALAEDAPVYQMPSAEPQSFRDNQAMENEVPEVENYGETLLQLLQQPTIASKEWIYDQYDYMVRTNTVVAPGSDAAVLRIRGTEKALAMTTDCNSRYLYLDPETGGKIAVAEAARNIICSGAEPLAVTDNLNFGNPEKPEIFWQIEKSADGISEACRKLNTPVIGGNVSMYNETNGEAIYPTPVIGMVGLVTNLKHITTQSFKEAGDIVYLLGETKDEFGGSELQKMQNGKIYGKSPSIDLAVESEYQQNVLAAIRAGLVASAHDLAEGGLAVAIAESAIGSNGLGADIKVSGNPVSALFSESQSRFLLTVKKENQQEFEKLVGATLIGEVTAEPVLNITQDSVTIISEQVESLEKAWKGAIPCLLN
>NC_021171|346610:356572|351880_353293_+|WP_015592164.1|DBSCAN-SWA
MLAELKGLNEECGIFGVWGHQDAASITYYALHSLQHRGQEGTGIVVTDGTKLDIFKGEGLVTEVFTSEVMSKLSGKSAIGHVRYATAGGSGYENVQPLLFNSESGSLALAHNGNLVNAKLIKSILEQQGSIFQTSSDTEVLAHLIRRSGERRIKEQVKSALKQIEGAFAYVIMTENEMMVALDPHGLRPLSLARLGDAYMVASETCAFDVVGAEFIRDVLPGELLIINDEGIKSEFFSENKPSAICAMEYIYFSRPDSNIHGINVHSARKRLGKKLAIEAPIVADVVTGVPDSSISAAIGYAEASGIPYEMGLVKNRYVGRTFIQPSQSLREQGVKMKLSPVRGVVEGKRVIMVDDSIVRGTTSRRIVTMLKDAGALEVHVVISSPPIKNPCFYGIDTSTKEELIASSNSVEEIRELIGADSLTFISTEGMLEAIGRIDTDKNCGQCVACFTGEYPTELYPESLQYYYQK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015592159.1|346610_347903_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.2e-19	26.3
WP_015592160.1|348052_348766_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HI61	Synechococcus_phage	7.4e-48	45.9
WP_015592161.1|348758_349013_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	1.6e-05	36.7
WP_015592162.1|349009_349693_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_015592163.1|349676_351896_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.2e-160	42.0
WP_015592164.1|351880_353293_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	7.0e-50	30.4
WP_015592165.1|353416_354442_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	3.9e-66	44.9
WP_015592166.1|354452_355037_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.0e-24	35.7
WP_015592167.1|355033_356572_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	6.2e-76	52.3

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_021171|3583108:3644239|DBSCAN-SWA
GTTAAAAGTTTTTTGCATCAGGCTTATTGAAGCCGTATTTTTCAAAAAACTCTTCTTTAAAGTCACCTAAGCGGTCTTCTCGAATAGCTTGTCTGACCTGCTCCATTAATTTTAACAGAAAATATAAGTTATGGTAAGTTGTTAACCGTATTCCGAATGTTTCGTCACATCGAATGAGATGACGAATATAAGCGCGACTGTAATTTTTACAAGTGTAACAATCACATTCCTCATCAATCGGCCCAAAATCACGAGCAAATTTGGCATTTTTAACAACCAATCTACCCGAGCTTGTCATCAACGTCCCATTACGAGCAATCCTCGTTGGCAACACACAGTCAAACATATCAATCCCACGAATAGCTCCGTCAATTAATGAATCAGGAGAGCCTACCCCCATTAAATATCTTGGTTTATCCGTTGGCAATAACGGTGTTGTAAACTCGAGGACCCGATTCATGACATCCTTTGGTTCCCCAACCGAAAGCCCCCCGATTGCGTAACCAGGGAAATCTAAAGAAACTAGGTCTTTTGCACTCAATTTCCTTAGTTCTTCGTATTCGCCCCCTTGGACGATTCCGAACAAGCCTTGATCATTTGGTCGTTGGTGACCTGTTAAGCAACGCTCGGCCCATCTTGAGGTTCTTTCAACCGACTTCTTCATGTACTCAAATGTGGCTGGAAACGGCGGACATTCATCAAAAGCCATCATAATATCAGAACCAAGATCATTTTGAATTTGCATTGCTTTCTCAGGTGATAAAAATAATTTATCACCGTTTAAATGATTTCGGAAGTGAACGCCTTCCTCTTCGATCTTGCGAAAATCACTTAAACTAAAGACCTGAAAACCTCCTGAATCCGTCAAAATTGCCCGGTCCCAGTTCATAAATTTATGCAGTCCACCAGCTTCTTTGACAATTTCATTTCCTGGTCGGAGCCATAAATGATAGGTGTTACTCAAAATAATTCCTGCTCCCATCGATTTAATGTCTTCGGGAGACATGGTTTTGACAGTAGCTAATGTCCCAACCGGCATAAATGCAGGTGTATCAAAAGAACCATGCGGTGTATGGACACGCCCAAGTCGTGCTCCTGTTTGTTTACATGTTTTAATTAATTCATAGGTTATCGCAGACAATTAATTCTGTCCTCCTTTTTTTCAGTTAAACGATTAACATTGCATCACCGAAGCTGAAAAATCGGTATTTTTCAGCAACAGCTTTTTCGTAGGCACGCAGGACATTCTCTCGCCCCGCCAATGCACTAATCAGCATAATTAATGTTGATTTAGGTAAATGAAAGTTAGTAATCATCCCATCAATTGCCTTAAATTGATAGCCTGGATAAATGAAAATATTGGTCCAGCCACTAGCTTGGGCAAACTTCCCGTCATGCGCTGAGGCAATGGTTTCAAGCGTCCGCGTCGAGGTTGTACCAACAGAAATAATCCGGCCTCCCTGATCTCTTACCCTGTTCAATAATTGAGCTGTTTCCTCAGTCATTTGGTAAAACTCAGCATGCATTTCGTGCTCGTTTATATCATTTACACTAACAGGCCGGAATGTTCCAAGTCCAACATGCAAAGTGATAAACGCAATATCAACACCTTTGTCCCTTAATTCGTTTAAAAGGCTTTCTGTAAAATGAAGACCTGCCGTTGGTGCTGCTGCCGAGCCACGCTCTCGTGCAAAAACGGTTTGATAGCGATCCCGATCCTCTAATTGCTCTTTAATATAAGGTGGCAACGGCATCTCTCCCAATGTATCGAGTACCTCATAAAAAATACCATCATACCCAAAATCAAGGGTTCTTCCGCCGTGATCCGAAGTCCCGACACATATAGCAGTAAGGCGTCCGTCTCCAAAGGTAATTTTCGTACCTTCCTTTATCCGTTTTGCTGGTTTGACAAGGGTTTCCCAACGATCCCCTTCGACTTGCTTTAACAACAATACCTCAACATTGGCTCCAGTTTCTTCTTTTGAACCAAATAATCGGGCTGGAAGGACTTTTGTATCATTTAAGACAAGACAATCTCCTGCTTGGAAATGATCGGTAATATCTTTAAAAATTTCATGTTTTATTTCTCCGGTTTGCTTATTTAAAATCATAAGTCTACTGTCGGAACGATTGACAAGTGGAACTTGTGCAATCAATTCTTCCGGTAAATCAAAATCAAACAAATCTACTTTCATCCTTCACCCTTCTTTACCTGTTACGTTCATATTCATATTTATCGTTACATTTCAGGTGTTTCCATATTAAAATGGCGATAAACTAAATCGGTCACCACTCGTCCTCTTGGTGTTCTTTGCAGAAAACCAATCTGCAATAAATAGGGTTCGTAAACATCTTCAATCGTTTGCGACTCTTCACCAATTGAAGCTGCAATTGTATCCAACCCTACTGGTCCACCACGGAATCTTTCAATAATCCCTTTAAGTAATTTATGGTCAATATGATCAAGACCTAAACGGTCCACCTGCAATCGCTCAAGCGATTCATTTGCGAGATGAAAATCCACTTCTCCATTACCATCTACTTGAGCGAAATCTCGAACCCTTCTAAGCAAGCGATTGGCAATCCTTGGTGTTCCACGCGATCTTTTGGCAATCTCTGAGGCAGCGAACGGATCTATTTTTGTTTCTAAAATTTCTGCCGTTCTTGTTACAATATTGGCAAGATCCTCAACTGTATAAAACTCCAATCTACCTAGCACCCCAAAGCGATCTCGTAATGGCGCAGAAATTGAACCTGCACGAGTGGTCGCCCCCACCAAGGTAAACGGAGGCAAATCCAACCGAACTGACCTAGCACTTGGACCCTTCCCAATCACAATATCCAAACAAAAATCCTCCATTGCTGGATACAAAATCTCTTCGATTGATCTTTGTAATCTGTGGATTTCATCAATAAACAAGACATCACCTGGCTCAAGTGCCGTTAAGATTGCCGCTAAATCACCAGGTCGTTCAATTGCTGGTCCTGAAGTCGTACGGATATTTACACCCATTTCATTAGCAATAATCGTCGCTAGTGTCGTCTTCCCCAGTCCTGGAGGGCCATATAATAAAACATGATCGAGCGTCTCCTGCCGAAGCTTTGCCGCCTTAATAAATATATCAAGGTTGGCCTTTATTTTATCTTGTCCAATATATTGGTTTAAGGTTTGTGGTCGTAAGCTTTGCTCATATGATTCGTCTTGGTAATCCGCTTCACCCGAAATAAGTCGTTCTTCCATGGTTCCATCACCTCCGTTTATCCTATTAAATCATTCTATATGGCGACTTTATGAATTGCATGCGAAAATAAGGTGCAACAATGGCTATCTTAATAGCTTTTGTAACGCCTTCTTAATATATTGGTCTGTCGTGAGCTTTTCTTTCTGAAGCTCTGGGGAAATTTTTCTTATTTCTTTTTCAGAATATCCAAGAGCTTTAAGCGCTAATGAGGCTTCTTCCCAATCTGCTAAGGTATGTCTATCAAAGCTACTGGCATCTTCAGTGAAAAGGTCTGGAAATATTTCAGGAACAACTGATTGTAATTTGCCCTTTAAATCTAAGATCATTTGTCTTGCCGTTTTTTTACCAACACCAGGGAATTTGATAAGGAAGGCTTCATCCTCACTTTCAATAGCATAAATCACCTGCTCAGGGTTCCCAGATGCTAAAATGGCTAGTGCTCCTTTTGGGCCAATCCCCGAGACATTTAATAGTTTCGTAAAAAGAGTTTTTTCTTGGCGCGCCTGGAAACCATAAAGTGCCATGATATCCTCACGAACATAATGATAGGTATAAATACGGACCTCAGTCCCTAATTGTTTTGAGAAAATAAATGGATTCGGAGTAATCACCTGATAACCAATTCCTTGGTTGTCAATGACGATGTACTCGGGACCCACAAAGTCAATGGTTCCCTTTATGTATTCAAACAAGTGCCTTCGCTCCTCTATTGTCTAGCTATTGCATTAATCCTCATTGTATCATAACACTTTTGCAGGAATGAATAAAAATGTTGCAACTGTATAAATTTCTATTCTATAATAATAAAGTCGTAAAATTATTCCAATTCTCACTGGAGGCCAATACAGATGAAAAGATTATTAGCATTCTTAACTATCTTCACATTAATGTTTGCTGTAGCAGGTTGCTCATCTACCAAAGATGATACTTCTAAAACTACTACAGAGAAAAAGGCAACAGAGAAAACTTCCGAATTAACCGATCAAGTAAAATCAAAAATGTATAATGCTGTTCGTATTGCTGAAGGAAAAGTAAACGAAGTATTTGCAAAGGAAATGGCTGCTGATGAAACAACACCAGTCCTTACATCCACTTTTGCTGATGAGGCTGCTGCAGAAGCCTTTTTATCAAAATATTACAGTGCAGATATTGCAAAAGAAATTTATACTTACTACGTAACAGATCAAAAAACAACTGATGGTCAAACAATCGTTAAGGCTGATCCTTTCTTTGCAAAACCAATCTTAGATACAACAAAGGATGATGTAACGGTCGAAGGCGATGCAAATAAAGCCACAGTTAAAACAAAAGATAATGTAACTTATACAGTTGAACTTAAAGATAATACATATGTTGTTACAGCCATTCAAAAATAATTAGTAAGGACCGGTTTTATTGAAACCGGTCCTTTTTATTTCTCTATTCAAATTTTGAATACGGCTTAAATGTCTCCAATACTTGCTGGTAACGATTCTTGGACTTAACAGGAATCCCTCTTTTTAACTGCTGTTTTTTTCTACTCTCAAGCTTACCCACATCAATCTGAAAAAATGAGTGGATTACTTTTGAATGTTTGGGTCTCCCATTAAAAATGGTGAGCGTGCCTTCTTTGGTGATCCCAAAGTATCCATTTGCTTTAAGTAGCGGGGAAATATCATCTACTTGGTTTCGGAAAATCAATATATTCCCTTGCTGTTCAATTAATTGCCACTGTTTGTATTTTTCTTGAATTTCCTGTTTTGTTAAAACAGATTCCATTACGATTTCCTCACCTAAATCTCCATCTAAATAGACTCTTTGTAAAATTACCTTTACTCTCTGAATCTCTGCCTCATGTCTAGATACCGCCTTCCCTTCTGCGCACCCAATTGACTCATGAAAAAAAACAAGCAGGAAGCTGGCTGCAACTGCACTTAGTACGGACATTCTGGCATTCATAAATGACCACCTCTTTTAAAAATAGGAAAACGGAAAACTTCAATCCATGACAATGTTATAATGACCATTTATTTGGAAATTATCCATCTACATCAGAATACTGGTTAATTATTAGTCTCCATAAAATCTAATCAAAAATGTCAAGTTTTTGGCAATGTTCGATAAACAAAGATATTTTACTATTCCGAATGTATAATTTGAATAAAAAGTAGTCCAGAGGTACCGGTTGATTATCACTAACAAAATCAAACACCAAAGCCGTTGATTGGCCTTGGTGTTTTTTACTAGACCTAAAGCTCATCCCTGGTGCTCTACATTCAACCCAAGTTTATCGTGACTGATTATTTACCGAGTCGAAAATATCTCTGATATTCATATCGATCCCGTCTCGAAGCCTGCCACCACGAATGTTATTCTCGATATCGCGAATTCTACTGAAGGTTGCTTCATCGGTTACTATGTTTACCGAACGCCCTTTTAAATAAGGCTGAACTGCTTGAAGCACTTTTTGTCTAGTTTGCGCTTCTTTACTAACATCCGCTACATCCACAGCCACCAGAACATTGTTTTTATAAACAACGCAATGGACATCTTGGACATTTGGAATTGTTGCAGCGACGCCATCAATTTTATCAGCAAGTCTTACTTCATAAACTGTGTCATTCGTACTTCGAAGCTTTCTTTGTTTTCCATCTAGATGTCCGTGGTAATTGACATCGCTTGTACTATAACGATTGTCCTTTTGAAAAAAGTTTCGATCCTTTGTCGCTAACGGCTTAGTTGGATTTTCAGGATTACCATTTTCATCTCTAACTTGAAGAATTCGACTTTCCTGGTTGCGCTCATATTTCCCCTCAGAGCCAAAGGAATGATCCATTATTTCTGTTACAGGACCGTCATTATCATCAAGAATACGAGCATTGCCATTATGATGCTTTTCATTTGAATAATATCCGAGTGGCTGTGTTTTTTGCACATGTCGTGCCTGCCCCGCAGACTCACCATTATTGCTACAGCCTGCTAGTGCTATTGAGATAAAGCCAGCAATCGGTAAAAGTAATGATTTTTTATTCAAGCGAAAAACCCCCTCGCGGCTATTGAGCCTTTAGCTCATTTTTAGCTTGTGTGTGAGAGGGTTGTTTCATTCTGTAAGATAAGTCCAGTTAAAATTTTGGAGGTGCAGCCGCTAGATTGCGTTTATGCTCTGACACAGCATGCAGTCGATCAATAATTTTTTGATCCTTTTCAGGAATTTCTTCCCCTTTTAAATACCGATCAATCATATTATATGTTGTACCCATTTCATTCTCATCCGTTTGACCTTCCCAAAGACCAGCACTTGGAGCCTTATTAATTACCTCATCAGGCACACCTAAAGCTTTAGCAAGCTCGCGCACTTCCCCTTTCGTAAAATGAACGAGGGGCACTAAGTCTACTCCACCGTCACCATATTTTGTGAAGTATCCAGTATGCCACTCAGCAGCGTTATCTGTCCCCACCACTAAATAACCAAAATTATTAGCAACTGCATACAAAGTGGTCATACGTAAACGAGCTCTTGTGTTTGCATCGCCTAATTTTGACTTTTCTTCATTCCAATCTCCCGTTTCTTTTAACTGAGATTCAATTTCCGAAAATAATGTATTATGAGTTTCTGTTAATTCAACAGTAAAATGCTTAATCCCACAGCTTTCAATTACTTTTAATGCATCTTCCCTGTCTTTAGGATTACTTTTAGTTGGCATAATTAATCCAACGGAATCATTAGGAAATGCCCTTTTTATTAAGTGGGTTACAACTGCTGAATCAATTCCACCACTTACCCCAACAATTGCCCCATTCGTACCTGACTCTTTCACCTTTTGCTGTAACCATTGCACCAATTTTTCAATGACTTGCTCCATCTGTTAATACTTCCTTTCGAGTACAATATTTCCAAGTTATTTTACCACATTTTTTAGGTCTTTTATCAATTGTCTTCTTAAATGAAATTGATCAACCGTTAGTTCCATGACAGGAAGTATTTTTTCAGGCGATTGGTAGGTCTTATCCTTAATAATTCTAGTCCATTCACGAAAAATATCAGTAGGATACATCAATGCTAGTAAAAACGCCCGGTTATTTAAATATTTATTAATGTGTTCATATTTTGATAATTCATGCATGGACCAATTAATGAATGGAAAAATTCTGTTCGCATACTGGAGCAGGTCAGAACCTTCATTTCCAATCGAAATTAAATCAAAATCAATTAAGTATAAGTTTCCCGATTTTGACTTTAAATAATTATGGTGGGCAACATCACCGTGTAGGATGACCGGTTGTAGATCATCATTTCCAAAATTAAGATTTTCATTTTTCAATCCCTCTAATGAAATTTTTGACCATTCCATTAACTCGTTAATCATTTGATCTTTTAAATAGTGCCGTAAAAGGGGGATATGTTTTTGGAAGCGACTACTTCTTTCATACCATTTTTCATATAAATTTATACGAGGTAACATCATCTCATACGATTTAGCCAATCTCTTGGTCGTACGGTGAAAGCGATTAAGTAATCGTATCCCTTCTTTTCGATCACTTGAAGATTGATACGAAAAACGGTCGCGATGGGGCTCGATGTATTCAATCCACCCAAAATATTTTTGGTTAAAATAGATGGGTGTTTCTAATATTCTGTAATATGAATAGGAATGATGAAAACCCTCAGCTTTTAAAGACTCAGTAAAGGCTTCTTGTAGATATAAGCGCTGTAAGGAAGAATATCCCTTTAAAATATACGGTTTATGATCTGTTTTAACAAAATAAACATGTTTACGTATTTGTTTTATTTCGTTGACTTTAAAAGGAACGCTCTTTTTTAAAATGTTGAGGAGACGATTGGTAATCAAATCGTCTCCACCATTTTTATGCTTCATACTCACTGCTTTCATCGCTTTGTCTAGGCATCGAAGTTGGACTTCCACCCATTTGACCAGTTCCGTAAGGACTCATATACAGGCCTTGTTGAGCGTATGGGGGCGAATAGATTTGGCCTTGAGGGAGTGGATAGCCCTGTGGCATCATACCTTGCTGGATAGGGACACCTCCTTGCTCAAAAGCTGGTGACCATTGAGGATATGATGGTCCCCCTGTTTCAATTGGGACATTCCCTTGCTGATACGGAACGCCTCCTTGCGGATAAAATGATGTTCCTGTTTGAACAGGTGAGATCCCTTGCGGATATGGATTTACTACACCTGGTTGCCCTGGCGCTACTCCTGGTGGATATGGGTTTAGTCCCTGTGAATATGGGGGTGTTCCCTGTACAAACTGTGGTATACCTTGATACGGGACCCCTCCACTAACATGTGCTTTCGGTCCACCGCAACCACAATCTGCTTTTCCTGCAAAAGGCGGTGGAGTTGTGTATTGTGTCGGTAATCCTTGTGTTTGTTGATATGGCATCATATCGGCTGACTCAGCCTGATATTGTGGAAAAACAGGTGTTTGCCCTTGCATTTGTGGATACATTCTTTCTGGGTACCCATATCCATAAGGGGTCTGGCCGTATGGGATTTGTCCATATGGTACGCCAGATCCCGGTAAGACTGGTGAAACGGGTACGGTCGGTCCTTGTGGATAGGAAGGATAACCATATGGTGCTTGCGCAAATGGCGCTGCTTGTGCAAATGGCGCTGCTTGTGGATACGCAGCAGGATATCCACCTGGTGGTTGGAACCCTTGTGCTTCAGAAAAACCTTGAACTGGCGCATTTGGCATAAATGATGAAGACTCATCATGCACATGTGGCACAAATGCAGAACCTTCTACTCCAGGCATGCCATAGTATCCTGGCATAGGTCCTTGGACTGGCGGACAAGGTGCAACTTGCGGATAAGGCGGACATGGCAAACCTGATCCTGGCAAAACCGGTGAAATTGGATATATATATGGCGGACATGGATACATAGGCTGTTCGCAACCTCCTTGTATTGGCATTTGTACGGGTACTTCAGGGCATTCTTCTTTGACTACTGGGAGAATATTCACTGGTTTAGGCGGCAATTGTGGCTGCGGTGGTGGTGGTGGTGGTTGTTGGATATTGGCCATATTCATCATGTAGTAATTATTGATGTCAATTTCCGGAATGATAGGCTGCGGCATTTTTGGGACGTAAGGTGCAATTGGTGCTTCTTTAATTGGCATCTCTTTTATTGGCATCTCTTTTATTGGAGCCTCTTTAATCGGCATGGCGATTGGCGCTTCCTTGATTGGCATTTGCATTGGTTGTTCTTTCACAAATGGCTGCTCTTTGATTGGCATTTCCTTTTTAGCACCCATACTGATTTTAGTTGCCGGTGCTCCTCCATACGGGGCTTCTTTTTTTATGGTTCCCCCTGTGGTTGGAACTTTTATTTTCATACCAGGCATTATCATATCCGGGTTACTGAGCTGGGAATTCATTTTTTTCAGCTCTTCAAAATTCACGCCGTACTTCTTGGCGATTTTCCAAAGAGTATCCCCTTTCTGTACGATATGGATCTTCACACGATTCCCCTCCTAAGGTGGCATAAGTCCATACATTGTATGTTGAAGTGGGCAAATTGCTAACAATCCACAAAAAATATTTATGCATTTTCAATAAATAATATGTGATAACTATTTTTTCATTACTTTTTATCGGAGGTCCTACTTAATGTAGTGGTGAAAGTATGGTAAAATTTTTAATCATCAGGGGTAAGGTGGGTACAAATATGAAAGAACAAAAAAAGATTTTAGGAGAAGAACGACGAGCTTTTCTTTTACAAATGTTAAAAGAAAGTAGTGTCCCCATTACAGGAAGTGAGTTTGCCTCCAAAACGAAGGTAAGCAGACAAGTAATTGTTGGCGATATTACCATTTTAAAAGCAAAACGAGAGCCGATTATCGCTACTAGCCAAGGGTATATTTATTTAAAACAACCTACTTCCTCTTCCATTTATGAACGTACGATAGCGTGCAATCATCCCCCGGACCGAACAGAAGAAGAATTAATCATTCTGGTCGATCATGGAGTCACGGTAAGAGATGTCAAGATCGAGCATCCTGTTTATGGCGATTTAACCGCTTCAATTATGGTGGCCAATCGGAAGGATGTAAAGCACTTTATGGATAAAATTAGGATGACGAAAGCAACCTATTTATCTGAACTAACGAATGGAATCCATCTTCACACCATTTCCGCCCCATCTGAAAAGATTTTAGATGATGCGGTTCAAGCCCTAGAAATGGCTAATTTCTTAATAGAATAAGAAAAGCGCAAGCAATCTAGCCGCAAGGGCGATGGAGCTAAACAGTTCTCTAGTTCAAAGTTTTATACTTCCTTACTTTTAAAAAAGATGGCTGTGTTAAAGCTCAATGTTGATTTTATGCACAATGTTGATTGGAGCGGAAGGTGCGAGACTCCTGCGGGAGCAGCGGGACAGGTGAACCCCACAGGTGCTTTAGCGCCGAGGAGGCTCACCGCCCGCCCCGCGGAAAGCGAGCATCCTGGAGCGGAAATCAACATTCTACTTTAACACAGCAAAAAAAACAAAAGGGTTTCGTCCACATCAAATGGACGAAACCCTTTTATTTCTAGCCTACTTTAGGTTATAGGAAGGATAGCTTCCTAGTAAGGTTACATTACAGCCTACAGCTTCAAGCTCTTGCATCGCACCAGGAATTAACACATCATCAACCTTCATCTCAATATCGATAATGAAGAAATAATTTCCTAACCCCGTCTTCATTGGACGAGACTCAATTTTAGATAAATTAAGCTTACGCCAAGCAAATGCTGATAATACTTGATGGAGAACACCTGGATGATCAGCAGGGAGGGTCACCATAATCGTAGTTTTATAACCATGAAAATGCGGATGATCCTCAGACAATGCTAAAGTTTTTTTTGCCAAAATGATAAATCGGGTATGATTGAATGATATATCGTGAATGTCTGGTTTTACGATGGTTAGACCGTATTCCTCTGCAGCCAAATCATTGGCAATTGCTGCTGCTTTTATTTCAGGATGCTGCTGAATATACTGTGCAGCTGCAGCCGTTGAAGTCGTATTTTCGCAAAATACACCTTTAAATTCTGAGTGTAAAAATTTATGGCACTGAGCAATGGCATGTGTGTGGCTTAAGATCCGATTGGTCTCTTTCCAGGTATCCTTATGATCAGGATGAACCATGAAATGCTGACGAATCGGCACATTAATTTCTCCAAGAATAGGCAGGTCCACTTCATGAACTAAATAATCCAAGGTTATATTAACCGAACCCTCAAGTGCATTTTCCAACGGAACAACTGCAAGATCCACTTCACCTAAAACAACCGCATCCATACATTCTGGAATGGTTAAATACGGTACTCCTGTGTATTCAGGAAACATTTTACGAACTGCAATATCTGTAAAGGTCGCCTTCGGACCCAAATATCCTACCTTCACGATTTCTCCCCCAATAAAAATCGGGTTGAAATCTAAGGACATAGATTCATCTATGCCCCAGATCCCAACACCTCAACTTTTTCTACAAATTCAAGCCGCTTAAGTTGTGTAAGCAACTCATCAAGGTCAATCCCCATTGTTGCAACATTTAACGAAAGTGTAACGTTTGCTCTGCCTTGAATCGGAATCGTTTGGTGAATGGTTAACACATTACAACCGGAAACAGCGACAACTTCCAGGAGTTTTGATAAAGTCCCAGAGCGGTCTTCCAGTTGAAAAAATAATGTAATAAGTCTTTCTTTCACAATCGTATGGAATGGAAACACCGTGTCACGATATTTATAAAATGCACTACGGCTTAAATCGACACGATTTACGGCGTCCCAAACTGATTCCGCTTTGCCTCTTTCAATCATCTCTTTTGCTTCCAGAGTTTTTTTCATCGCCTCAGGCAGAACGTCTTCACGAACTAAAAAGAATTTTTTATCGAATTTATCATGTCTCATTTCTCCACCCCGTAATTGCGTAGGTCTATTCAATAAACTCGAATTCGTAGTTTAACAACTGAACCGCATCTCCATCTTTCGCACCTTTTTGACGGAGCGCTTCGTCAATTCCCATACTACGAAGTTGACGTGCAAATCGCTGAACTGATTCGTCTCTTGAAAAATCAGTCATTTTAAACAATCTTTCGACTTTTTCCCCAGAAATTACGAAGGTTCCGTCCGACTCACGAGTAATCAAGAATTCATCTTGCTCCGCTTCATGTTTATAAACAACGCGATGGAGGCCAACTTCCTCTTCCTCTTTCTCCTCTATTAGCGGGAATTCAGGAGTCTGTTCGATTTTATCGGCAATCTCAAACAACAAATCACGTAATCCTTTTCTAGAAATAGCTGAAATAGGATAGACCGGATATTCATCATTTAGCTTCTCTTTGAAGACCTTCAAATTCTCTTCTGCCCCTGGCATGTCCATTTTGTTAGCAACGATAATCTGTGGACGTTCCATTAAGCGTAAATTGTATTGTGCCAATTCTTTATTGATTGATAGATAATCTTCGTAGGGATCCCGCCCCTCTGTTGCTGCCATATCAATGACATGCACAATGACACGAGTTCTTTCAATATGACGTAAAAATTGATGTCCAAGGCCAACACCAGAATGGGCCCCTTCAATTAATCCTGGAAGATCCGCTAATACAAAACTTCTGCCATCTTCCGTTTCAACCATTCCCAAATTTGGGACAATCGTTGTAAAATGGTATTCGGCAATTTTTGGTCTCGCTGAAGAGACAACCGATAGAAGTGTTGACTTACCAACACTTGGATAACCTACTAAGCCTACATCAGCCAAAAGCTTCAGCTCTAACATGATGTTTCGTTCACGGCCTGGTTCACCATTTTCGGAAAGTTCTGGTGCCGGATTAGATGGCGTAGCAAATCTTGAGTTTCCTCTACCACCTCTACCGCCTTTTGCAATGATGGCTCTTTGTCCGTGCATCGTTAAATCACCGATGACCTCGCCTGTATCCTCATCTGACACGACTGTTCCCGGTGGTACTTTCACGATGAGATCCTTAGAGTTTCTCCCGTGCATATTTTTAGACATCCCGTGTTCACCACGTGGTGCTTTAAAATGGCGTTGGTAGCGGAAATCCATTAGCGTACGTAAGCCTTCTTCTACTTCAAAGACAACGTCCCCGCCTTTTCCACCATCCCCACCAGCTGTACCACCTTTAGGGACATATTTTTCACGGCGGAATGCAACCATTCCGTTCCCGCCGTCTCCGCCTTTTACATAAATTTTCACCTGATCGACGAACATTTTTGTTCCTCCCGTCTGTACTAAGTACAAAACAAATTTTCTTTCAAGACGAGAATCTCTCTTTTCATAACCATTCCTATCTAAATGGCATAAAAGTATCTAATGCAAGTTCCTGTTGAGAGAATTCCAATACCTTTATCGTAAGTTGGTTGTTATGATTTGCGTCTAGAAACTGTTGTAACTTGTTCTTATCCTTTATTATTCCGCTAAAATCAAAAAAGAAACGAATTCCATTTTTTTGTGTTTCAACGGAAACTGCAAGGTTATTTTCATGAATTTCATCAACTGCTGTATGTAAGCATTCAAAAAATGAACTTGTCCATTCGGAGAGAAGATGATCATCCAAGCTTAAGATAACGCCAGATTCATGGACCACTTCATACTCAAGCTGAAAGGAGTGTGCTTCCCAGTTGGCTGTAAGTAGTAATGATGCAAAACGAGGAATTTTAAGGTTCGACAATTTTGCCTCTTGTTTTGTCTCGATTACAATTTCATCGATAATTTGTTTGACACGCTCTATTTTGTTTAAAGCGAGATTACCTTTAATTAATTGTATTTTATTCAACCAGTCGTGCCGTGCATGTGCAAGGACTTCGACGGTACTCCAGTCTTTTCTCATACCTGCACTCCTAAATAGTCATATTAGCATCATAAGGCTACTTGCTGATAGTATATCAAAAAACAGACTTTGCGTAACGAAAAAAGAAGAATTTAGCAAAAAAAGCGGAATTACGCGGCTAAAGACATATTGACTGGAGCTCTAATAAAGTTAATAAAAAGGCTGTGATAAAGCTCAATGTTGATTTTTTTCCCAATGTTGATTGGAGTGGAAGGCACGAAGACTCCTGCGGGAGCAGCGGGACAGGTGAGACCCCACAGGCGCTTTAGCGCCGAGGAGGCTCACCGCCCGCCCCGCGGAAAGCAAGTGCCTGGAACGGAGATCAACATTCTAGTTTAACAAAGACAATAAAAAAGAAAACTCTAACCGAAACGGTTAGAGTTCACTGTTAAAAAGCTTACGCTTCTTGTGCTACAGGATAAACACTTACTTGTTTTTTGTCGCGTCCTACACGCTCAAATTTAACGACTCCGTCAACTTTTGCATATAGAGTATCATCGCCACCACGACCAACGTTTGTACCTGGATAAATCTTTGTACCACGTTGACGATAAAGGATAGATCCACCACTAACGAATTGGCCATCAGCACGCTTAGCACCAAGGCGCTTAGATTGTGAATCACGACCGTTTCTAGTAGAACCTACTCCCTTTTTAGAAGCGAAAAACTGAAGATCTAATCTTAACATTTATTCCACCTCCTACTTTTTGAAGGTTATTTTTATATGCTTTCCGTACTCTCTTTCAATTGTTTTCAATGAAACAACCATTGCTTCAAGAAGCAATTGAACCTTCTCTTGTATATCCTCTGCTAGATTGTCTGGGAATACACATCGGAGAAAGCCATCTTTTCCTAGGTCAACCTCTGGTACGAAGCCAGTTAACACTTCGATAGCATTAAGGGTACCAAAGGAAACTGCGGATGCTCCTGCACAAACGATATCCTCGCCGTGATCAGCAAAATTGGCATGTCCACTCATTGAAAACATATGAATTTTTCCGGATTCAGTACGATTAATCTTAATTCGAATCATCGTATTAAACCTTACGCGTTGATTGCTTCAATCACAACTTTTGTGTATGGTTGACGATGACCTTGCTTTTTACGATAATTTTTCTTTGACTTGTACTTGAAAACGATGATTTTCTTTTGACGACCTTGTTTTTCAACTTTAGCTGTAACAGTTGCGCCTTCAACAACAGGGCTACCCACTTTTACAGTTTCGCCGCCAACGAAAAGAACCTTGTCAAAAGTAACTGTTTCGCCTGCTTCTGCGTTAAGCTTTTCAATATAAACAGCTTGACCTGCTTCTACTTTAATTTGCTTACCGCCAGTTTCGATAATTGCGTACATAACTTGCACCTCCTTATAGATTAAGACTCGCCATTACAGGGGATTGCTAATTAAAGCAAAAACTTAGTACCTGTTATGTGCGGTGTGCTATAAACATAACATTAGAATCCTATCATAATTATCCTAATCATGTCAACAGAAAATCTTGATAGGCAAAGGATACCACCCTACTATTTTTACAGATAGCTCTGTTAAACTTGTCTGTTGATTTCCGCTCCAGGATGCTCGCTTTCCGCGGGGCGGGCGGTGAGCCTCCTCGGCGCTAAAGCGCCTGTGGGGTCTCACCTGTCCCGCTAATCCCGCAGGAGTCTCGCACCTTCCGCTCCAATCAACATCGTTACTAAACAACGATGAGCTTTAACACAGCCTTACAGATAAAAAGGTGATTACAGCTGGATTCTCGCCTTAAGCTCCTGGACCTTGCCAAATTGCCGAATAAGATAAAAAGGTTTGGCACTTGATTGAAGCGTGAGAAAAATGGTCAAACCTAGCAGTTCTTGAAAACGGAATAGATGAACGTTATTTTCCCCAGAAAAGACAGAACGAACTTCTTCCGTTGTTTCAATCCAAACCGCTTCATTGTCAGTAAAACGATGTTCCCACAGCTCCCTCTCAAGCCGGAACGCTACTGTTTCTGGGCTAAGGACCCGTCCACTCCCTTCACACACCAGACAGGCTACCGTCAAGGCTTCTGACAAGGCTTGTTTCGTCTTCTTTCGCGTTAGCTGCAGAATGCCCAAAGCAGTGAAACTTATCACCTTAGATTGCTTCTCGTCCTTACTTAGCTCTATTTCTAATGTTTTTTGAACTTGCATGCGATCCTGTTCATTTTTCATATCAATAAAATCGATTAAGATGATTCCGCCGATGTCTCGCAAGCGTAATTGTTTGGCTACCTCCACTGCCGCAACCAAATTGGTCTTAACGACAGTTTCTGCTAAATGATTCTTTCCAGAAAATTTCCCGGTATTTACATCAATTACAGTGAGTGCCTCGGTCTGGTCTATTACCAAATAGGCGCCATTTTCCAACTCAACATTCCTATGTAAGGCTTGCTCAATCTCATGTTCAATATGATGAACATGGAATATATTCTCTTTCCCCTGATAGTAGGTTACAGTGACATTCTCTCGCACGAACTTTTCAAGCCTTTGTTTTAGCCCTAGGTCATCTACTAGAACTTCTCCTGAAGTAAGGATTCGACATTCCTTCTCAATTTGAGCTAAAAATAAATCCCTTTTTACGAGAATGCCTGGTTTTTTTCGTTGCTCAGAAGCCTTTATCAAGTCAGCAAATTGTTTCCGAAGTTCCTCAATTTCTGTGCTAACTTTCTGTTCCGATTGCCCTTGGGCAGAAGTTCGGATAATAAGGCCTTCCTCTTCTGTTTTGATACGAGTGGCCATTTTCTCCCATGCTTGTCTTTCCAATTTGTCAGGAATTTTTCTTGAAACCGAAACGGACCTTCCTTTTGGTAACAGGATCACCGACTCACCATAAAGTTCTATGATTCCTGTCAATCTTGGACCTTTTGTGCCGGTTTCGTCCTTTTCGACTTGAACCAATAATTTCTCTCCTTGAAAAGAAAATGCCGATACAGACTTATTTCTTTTTACTTCACCTGAATCTTTCGATAAAACATACCTAGAAAGTTTTTCACGTTGCAGATATCCATTTTTTTCTTCACCAATATCAACAAAGACAGCATTCATTCCAGGGAGAACCTTGGTAACTGTCCCTAAATAAATGCTGCCAACCGATGACTGCTGTTGCGGCTGTTCAATGACTATTTTTTCAACGCTGGTTTCACTAACCAATGCAAAACGTTTTTCCGTTAAAGCATGATTTACAATTAGTTTTTTCAATGGTTTGCCTCTCTTTTTCGTCAGAACGATTAGTATGTGTAAAGTAAATCACGAATTTTGGCTGTTAACAATTTTTCCGCAAACACGGCATGCAATATTTCATTTTCATCGAGAATGGCTTTTTCTTTTCCGTTTTCTTCGATAATGATGGGATGCTTACAGCCTCGACAAAACCGTTCGAGGACATGCACAACCAGTTCATCTTCGGCAACCTTAAGCGGTCTTAACACGCGCAGGTCGCTCCTTTTCCCATAATAGCGCTCCAGTAAAAAACGCATAAAAATAAAGCGATGCTGCTTCCACTCATGATAAAGGGAAAATAATAAAAAGGCGAGGATTATCCACACGTTTAAATTATTTGGCATGAGCACTATAGTGAAACCGGCAAACAGGACCATACAGACTAGTGATACCAGAATGGTCATTCGATGCGCGATAGGAAAGGATTTGTAGTATGACAACAGCAAAAACACAAGTTTTCCCCCATCCAATGGCCAGATTGGTAACAAATTAAATAGCAAAACCATCATATTATAAGAGAGGAACAATTTATAGTGTTCAGGACTAAGCCAGGAAAGTTCATAAAAACAAAAAGCACCTCCGATCAACCAGATATGTTGGAAAGGACCTGCCAATATGACGATTGCTTCCTCAAACAAAGGACGGTTACCATGTTCATCCATCTCCGCCACACCACCAAATGGTAGGAGTGTAATTTTTTTTATTCTCCATGAAAAAACAGAAGCTGCCACCGCATGTCCCAATTCATGAATAAAGATAATTATCAACAACATCGACAATTCTAAAAATCGTGCCGTCAAAACTGCCAGTGCTATGACAAGCCATAGGAGCGGGTGAACATTAACTTGTTTTAGCAATTCAAACAGCTTATTCAAATTGAATCACCTGGATCGGATCAACAAAATTTTCATCCTTTTTTATCGCAAAATAGAACGCCCCTTTAGCACCTGATTCAGTGTTGGTGACTGTCCCAACCTTTTTACCTTTTTCAATATATTCATAAAGACTGACAGAAATATTGTTTAAATTTCCATACCATGACTCACTTTTGTCAGCATGCTGAATGATCACCGTTTTTCCGAAACCATCCTTTTCGCCGACAAAACGAATAATTCCTTCATTCATTGCCTCAACTGCAGCATCTTTTGGCGTTTCAATCGTAATGCGTTGGCCACTCACATCAAAATCCTCCAATATTTTCCCTGAAGCGGGTAAAGCATAGTGCTGACCAGTTGCAACATTAGTGGTGTCCTTCTTATCTGATACTGGAAATAACGCTAAAGGTTTGCCAAACTTTCCTTCATACCAATTTGAGACAGCCGCAAATTGAAAATCCTTATCGAGCGATTGTTTGACAAAGGCTCGGGCAGGATCCAATGAAGCTGCGTGATTTCGAAACAAAATAGCCATGACCAGAACTAAACATGCTGATGTTAGCAATTTTAAAAGAAAAACTTCCTTGCGAAAAAGGGGATGGTTTTCTTCGTTAGGTCCTGATTCATAGGTTGGTAGCCGGTCAAAGCCATGCTTTTCTTCATCATCAACGGTCAACAAACGTTTGTGAACCTGACTTGCCTGCCTCTCCCGACCTTTTTTTCTATTCTCTATTCTTTTTCGGACATCATCCGCTCTAGAACGCATATTCACCCCACCATTTCTATAAAACATTTGTACAAGTTTATGAAATGACAGTTGAGAGTATGCCTAAATGAACAAAAGCGCAAACTCACGATAAGAATGGGGCTGGCCGAGTCCATCCTTGTTAAAGCAATCCACAGTATTGAAATTTATTATTTTGTAAAAAACAAAAAATGCCCGTCTTCGATGAAGAAATCGAAAACAGGCAGTAATTATTTTGCACCAAAGAAACGCTTAATTTTTGTAAAAACACCTTTTTCATCAGCCTCAAGAGATTGTAATGGGATAGACTCCCCTAAAATTCTTCTGGCAATGTTGCGATAAGCGATTGATGCCTTGCTATTTGGATTTAGTGCAATCGGTTCGCCGTGATTAGAAGCTTTTATTACTTCATCATCATCTGCCACAATACCAATTAAATCAATAGACAAATGTGCCGTAACTTCATCAACGTCAAGCATATCCCCGTTTTTCATTAAATGGTTACGAATACGATTGATGACTAATTTCGGCGCTTCCATATTTTCTTCTTTCTCTAACAGTCCAATAATCCGATCTGCATCGCGAACAGCAGACACTTCCGGAGTGGTAACGACAATCGCCCGATCAGCTCCGGCAACGGCATTTTGATAGCCATGCTCGATACCTGCTGGACAGTCTATTACAATATAATCATAGTCCTGCTTCAGTTCAGTGATTAGTTTCTTCATTTGTTCGGGTGTCACCGCTGTTTTATCAAGTGTCTGGGCTGCAGGCAATAAATAAAGCAGATCCTCAAACCTCTTATCCTTAACAAGCGCCTGATGAATTTTACATCGACCTTGGATTACATCAACTAAATCATAAATAATACGATTTTCAAGCCCCATTACAACATCTAAGTTTCGGAGGCCGATATCGGTATCGACTAAACACACACGTTTTCCTTGCAAAGCCAGAGCAGTCCCTAAGTTCGCAGATGTGGTGGTTTTCCCAACTCCACCTTTTCCAGAAGTAATGACTATTGCTTCTCCCATATTAAAGTCCCCCTTCCAATCTTGTTAAATTTGGTCTAAGATGCATTAAAACTTGTATTCTATCAACGACAATTTGTCGGTTATCATCAATAAAAGCACACTCTAACAAACGCTCTTCTGTTTCGGCAAATTGATCGGGTGATCTATTGATACAATCGCTAATGCGAAGTTGCGATGGCTTCATGATTGAAGCAGTAATAACGGCTTGGTCATCTCCAAAGCATCCGGCATGGGCAATTCCTTTTAGGGTTCCCATCACAAATATATTACCACCCGCTTTAATCGTACCACCAGGATTAACATCACCAACAAGTAATAAATCACCAGGAACCTCAAGTACTTGACCTGAGCGAATGATCCGGTTAACTGATTTAATCTCTGATTCAGCTTTTTTCCTTTTTGCTTCTTCAATTGTAATAACATTGCTGACAATTTCATCAACAACTAGATTCTTTTTTTGTCGAATGAGGTCTTTAATCTCTTCATTTTGTTTTTCTGTTAAAAGGCGATTTCCCATTTGCACTTTCACTGAAGTGAGGGGCTGATCCTCATTTATACGAGAATTAGCTGAGAGCTTCTGATCCAGTTCTTTTTTTAGCTCATCGTAAGAGCATGAGTCATCGAGATGCAGTATTATTCCGTCTTTAGTTCCTTTAATGGTTACATTTTGCATTTTTTTCATGGTAGAATGTTCACCTCAATGATAAAAAGAATTCGACAGGAATCTGAAAAATCCTTTTTAATTACGCTGATTAGATTTGTTTTTTCGCGACAAAAAACTATTCATTTCGCAACTGATCTGCTAATTTTTCAAATTGTCTCTTTAAAGGATAAGCCACCAAAATGATAAAAATGAGATTCAAAACAAGCGTTGGCACTAATCGGTTCCCGAAAAAACTTGGAAATCCCATGGTGGTCCTATGTATTAAAAAGTTCATTTCATACACACCAATCTCAAGGAGGCCAACGCCAAGAAGAGTGACAATAGATACGATAATGAGGTTTGTTTGAAGAACTTTCATTATTTTAGAGATCAAATAAGCGATGACTGGGAACATAAATAAATAAATCCCCACTACTTCTGTATAAACTACATCAAAAAGCAATCCAAAGATGAATCCATATAAAATCCCAAGATTTCTGTTACCATAAATCGTCAGAAATAAAATCGCCATTATTAACAAATGCGGGACTAGGATATGCTGACCACTAAAAAACTTAGCCGGCATGAGTTCGATAAAAATACTTTCAAAAATGAAGCAGCCTGTGAATAATACGGGAAGAAGAACTCTTCTCACAGCTCCTCCCCCTTATCATCTACCATATCAGAGCTTTGCGGCTGTGCCATTTTTCTTTGAATGACCATGACATTCTCAATATCATAAAAATCCGCACCCGGTTTTATATAAGCAGTTTGCGTTAATCCATATTCGTCTGGAACCACTTTAACAACCTTACCGATTGGAAGACCCTCTGGGAAAATACCACCTAATCCGGAGGTAACCACGTTTTGTTTCTTAGCCACTTTGGCATCAGCTGGGATCTGTTTTAACAAAAGTAATTTCTTTTTCTCGTCATACCCCATGATAAGGCCATGGACTTCCTGTTCGCCTCCCAAAATCACCGCAGATATCCGGTTCTTAGAATCGTTTGCACTTAATAGCTGTACGGTAGAGGTAAACTTGTTAACCGAATTAACTTTGCCTATCAATCCACTTGCCGTAACGACCGCCATTTTTTTCTCGATTCCGTTCACACTACCTTTATTAATAATCACTTGTTCGTTCCAACGATCTGGATTCCGTGCAATAACAGTAGCTTGGGTAGGGTCATAGTCTCGTAGAGTTTCCTTTTTGCCTAAAACATCATTTAGCTTTTTATTTTCCTTCTCTAGTAGCTGCACCTCAGCTTCAAGTGAGGCAATCTTGTCAACACGTTTCTTTAGTTCCTTATTTTCATTATATGTATTCTGCAAATCATTTAAATTTTCGAAAAAGCCAGCAACATAATTGGCAGGCTTAGAAACAAGGCTTTGTACAAATCCGGTCGTGTCCTTCATAAACTGCTCTGGCCAAGTGAGTTGCTTTCTATCCCGTATAGAAAAACCAATCAATGCCACGAGAATAATCATGCTGACGAGCAATATAATCAGTCGTTTATTTAGAAAAAACTGTGGCATGATTTACACCTCTTTTTTTATAAAATAAGAAAGGATAGCTAAGTACCTAATGTGGCACTTAGCTTTCTGTTTTGTTTAGCTCCAGACCCCATCGGCGTCTTCCGCTTTTCGTTTTAACGTGAATCTCTAGCTTTGTTTTTAAATAAATGAATATGGTCAAGTGCTTTTCCTGTTCCAATCGCCACACAATCGAGTGGGTTTTCTGCAATGAGTACCGGCATTTTTGTCTCTTCACTAATTACCTTGTCCAGATTACGGAGTAACGCACCCCCGCCAGTTAGCACAATACCCCGATCCATAATATCTGCGGCAAGTTCTGGTGGCGTCTTTTCAAGTGTAACCTTTACAGCATCAACAATCGCATACACTGTATCATGAAGGGCCTTAGAAATTTCATCAGCCGTAATTTCAATCGTTTTTGGAAGACCAGTCAATAAATCACGACCACGAATTTCCATATTTTCGATTCCTTCGGGGTCACCGGCAGAACCAATTTCCATTTTAATGTTTTCTGCAGTTCTCTCACCAATCATTAAGTTATAATGCTTACGGATGAACAGAATAATGGCATCGTCCATTTCATCTCCAGCAATTCGAATGGATTGACTAGTAACAATTCCTCCTAAAGAAATAATTGCTACCTCAGTCGTTCCTCCTCCAATATCAACAACCATGCTCCCCGTTGGCTCCCATACCGGCAAATTAGCTCCGATAGCGGCTGCAAACGGCTCTTCAATTGTATAGGCATCTCTTGCTCCTGCCTGACGAGTCGCGTCAATAACAGCACGCTCTTCAACAGCAGTAATTCCAGATGGCACACAAACCATTACATATGGCTTTCCGGCAAATAAGCCCTTTGTTTTCGTTGATTGGCGAATGTAATATTTCATCATTGTTGCAGTCGTTTCGTAGTCAGCGATTACGCCGTCCTTCATCGGACGAAGCGCCACCACATTCCCTGGGGTACGACCAATCATATTCTTCGCGTCATTTCCTACCGCAACAATTTGTTTAGAATCCGTTTGAAAAGCAACAACAGATGGCTCTCTTAAAACAATTCCTCTTCCTTTTACATAGACAAGCGTGTTTGCGGTACCTAAGTCGATTCCAAGATCTTTCGTTCCAAATCCAAACATGGTTTGTATCTCCCCTTTTTTTCAAAAACAATGTAAAGATAAGCTCAAATATTCCAAGAATATTCGCACATGATTTTAGTTTTAGCGTTCATTTTTAGCCTGTTTTTGTCAAAAAATCATAAATAATATTATATCGTAACGCTAACCAAAATCATAGTGCTATAAATAACCTTTTTCCTTTAAACTGACATATTTATTCTCACCAATTATGAGATGATCTAGCAAATCAATCCCAATAATTTTTCCACACTCAGCTAAACGTTTTGTAACTTCAATGTCCTCGCGGCTTGGCGCGGGATCTCCGCTGGGGTGGTTATGAAGGCAAATGATGGATGCTGCTGAACGGCGGAATGCTTCTTTGTAGACCTCGCGAGGATGGACGATTGAGGCGTTTAGACTGCCGATGAAGATCGTTTGCTTATGCAAAACTTGGTTTTTTGTATTTAAATATAGGCAAACAAAATGCTCCTGCGATAAGAAACGCATATCATTCATCACCAACTTAGCTCCATCTTCTGGGGAACGGATCACATAGCGGTCCTCATGAACCAAGTTAGCAATGCGTCTACCAATCTCTACAGCTGCCAACACTTGAATTGCCTTTGCCGTCCCAATTCCTTTAATAGCCGTGATTTCTTCTAAAGAGGCCTCCTTCAACAATCGTAAGCCTTCAAAATGGTTAAGCAAGCGATTTGATAATTGCAGAACCGATTCACTCTTTGTTCCTGTTCGGAGCATGATTGCTATTAGTTCATGGTTCGACAGGCTTTCCGGTCCACTGTTCATAAATCGTTCCCTTGGTCGTTCATCCTGCGGAAAATCACGAATCATGATTGAATCTGTATTCAATTAAATCCTCCCTTTCTATACAGGGAGCTCATAATGAGGGGCAAATTCCTAATAGGGCAAAACAAAGCCTGCCTTCTGTAATTCTCTTATTGTTTTCGATACAGGGAGGCCGACTACCGTAAAATAATCCCCAGAAATCCGCTTAACAAGCATACTTCCAAAGCCTTGAATTCCGTATGCCCCAGCCTTATCAAAAGGCTCCCCGCTATTGATATAAGCTTGAATTTCTGAATCATTTAAATCCCAAAACGTGACATCTGTTTTTTCATAAAAACGAACGGTTGTATCAGCTGTAACAATGGCAACTCCTGTATAAACAGAATGTGTGTTACCCGATAGCATTTTGAGCATTTTAACTGCTTCAATCTTATCTTTTGGCTTCCCTAATACCTGATTGTTTGCGAAGACAATCGTATCAGCACCTATGACAATAGAATCACGATGCTTTTCGGCAACATCCGTTGCTTTTCGAGCCGCCAAATCCATGACGATTTCTTCAGGTGCTGTACCTGGTAAAAAGCTTTCATCTGTTTCACTGCTGGAAATGTCGAAGATTAATTGAAGATTTTCAAGAAGTTCTTTTCGCCGTGGAGATGATGAGGCTAAAATGAGGTGTTGCATGATGAAATCACCTTACCTTTCATTGTATTATTTGGGGAGATACAGTCTCATCGTATCAAAATTTGTCATCACAAACAATTTTTTATATAAAAAACCATATTTTCTTCAAAAATAATGAGCCTGTGGATATAAATATCCAATCAGACCCATTTTTTATTGCCCGGAAAATATTCGACAAACTCAATTTGATCCGTCATTTCGTCACAATGCTTGGTAAGCTGTTAAAATTGAAAGAAGCTGTTGTTGAAGCGAGGTTAACTTCTGCTTGCCAACCGATTTCTCCATTGAATTGATATTTTGGGTCGCCGCATCAACTTGTACCTTTAATTCCTTGATTTTTTCATTTGATAATGTGTCTTTTTTTGGTGCCAATTTTTTAGACTGTTGATTGATGCTATCCAACAATGCTTTAGGGAATGAATCGGTGGCAGAAGCGATAGAGGCGGCTGTTGTCATCGTTTCAAAAAGGAGGGGGATTCCTTCAATGTACGTCTTTTCCTGCACCTGAAGCCCACTTATTTCATGTCCACTAAAGCTCATTTCCTTTGCGATAAATTCCGTCACTCCCGATTCCTTTAAGATCTCTCCAAATTCCTTGGCGTGGTCCTTTGTATCCGCCACACTTAACAGTAGGAAGGACTGACCATTGCTTTCAAAGGTTGCTGCAGAGGCACCCTTCTCCTTCAGTGAGTTTACTATTTGAGTGGCTGAATCCTTATTTGAATATACACCCTCTTGGACGACCCATGTTGTGATGGTCGGCGGTACAAGTGAAAGCTTGCCTGATTGTTGCTCTGCTTGTTTTTTCTCTGGTTCTGGAGTTGTTGTCGGTTTTTGAACAGTACTAGTTTGGGCTGGATGTTCAATGAACACCAGCTTGAGCATGGTGAAACCAAAGCTTGTCCCAAGCAATACCGCCAAAAAGACAGCTGTGAAGATAGTCGTGAACATCCTCTTGTCAATTTTCCGTTTTCCAATCGGCCATTTTTTTGACGATTTCTTTTGGGAATGATTCGCCTCCGCTGTCATTTTGTATTCTTTAATCTTTCGAATGTCGGATGTTGAATCAGGCAGAATCCAGTCAAAGCTTTCTTCGCTTGGGTCATGAGCTACCGCTGCTTCACTTATAGTAGTGAAATCTTCACGATCTTTTTGTGGCATCTTTACTGGCTTTGTCTTTTCAAATCTTTGTTCCATTGGCACCTTTTCAGTTGTTACTATATCTTTCCTATCATTTATGAATTGATCCTGCTTCCGATCAGATTTCTGGCGAGTTTCTTCAAAGGATTGCTGTTTCCCGTTGATTTTGATGGTAATGGTTTTACCAGGTTCCCGCTTGTCCACATGTATCCCTCCTTGCGCCTGCGGTTAATTGGTTTCATCCTATCATATCGGCAAAAAAAAATAACAAGACTTTTGTCGTCTTGTTATCGAATGCTTTCGCCAAATTTTTCACTAGATTTAGCTGTTACATATGACTATTTTGTTTGAGTTTCAGCTAGGAGATTCTAGGAGACTATAAAGGATCTGATTTAGGTACTACTAATTCTGGCAACTGACTCTGCAAATCGGTCAATGTTGGCATATAAAAAGCAGAAAGCGTAACTGTAAAAGATAGCTTTTTCTTTTCTGTGTCTAAATTGGTTTTTTCCCCACTTCCAGTAAATCCGACAGACTCAATAACAATAATTCGTGTCGAATTCTCCAATGTATTGATAAATATTTTCAATTCATCATAGCTAGGTGACTCAACTTGTAACGTTACTGTTAGCTTTTTGATTCCTGTCGGAACTGCCGCCTTTTGTGTTTGTGCAGTAGCTTTGGTTGTGCTTGCATTAATTTGCTCTGTTGTTTGCGGCTGGCTATCAGTGTTTTCATTCTTTTTGGTTGTATCTGATTTTTGATTGGCGTCAGTAGCGGCTGGCTGTTGCTGGGTTGTGTTTTGCTGTGGAACACTCACATCAGCTTCTGAAAAAGCCATATTCTTAATCTCGCTTCCAGATACGACCTCTGCTTTTTCTAAATCAAAGATTAACTTCTCGGACTGTGGCTTAACCGGAACCTTCCGTTGAAGTGCCGCCACACTTTCAACCGTAACTGGACTTGATTCTGTTGGTTTACTCTGAAGTGCTGTCAGCAAATCCTGTGCTGATTTTAACTCCACAGACTTGGTTTCAATCTCTTCTTTTTTCGGGCTAAGATAGAAATAATAACCTGACAAAATCATTGAGATGGTTAAGAATATGGTGACCATCAAAATGATGATTTCTTTTTTTGAAAAGCGAAGGGTCATGGAGCATCCCCTCCCTGCTGGTCTTTCTCGGCTTTTTCTTCTTGATTGATATAGTCCCGATTCAAAGTGATCTGATATTGACCAATGTACCGAGGAATGTATTGGCTCTGGTCCGAAGTGGTTTGTTCTGAATCAATCGTTTTAGTTTGTTTAAGCTCACTCACAGTCAGTGAAGATAGCTTTGCTTCAGAAATCCATTTGGAATCTAGCAAAGTTTTATAAAAATAAGCTGCATCCTGACTCGTATCAAACTGGGCAGTTAAGGTTACTGTGCCTGCTTCCGTATAAGCGATAGTTTGGATTAAACCACGCTGAAGCAGGAGAGAATCGATGTCCTTTAACACAGGAACAGATTTTAACGGTTCTTCATTAGCCCATTTTACAGCAGCTTCGAGCTGTGTGAGGGAAGCCGAGGCTTGAGCCGTATTCGTTTGCTTAGCTTTTTCAGTTTCCGCTAGCTTGTTCACTGCAAAAATTTGGTTTTTTAGACTCTTCAACTGATTACCTTGGGTGTATCCTTGCCAAAATATAACAATACCTGCTACCAGCAAAATAAAAACCGCTGAAAAAATGATCGTCAAAAAAGCTACATTTTTCGGTTCTTTTTTTGGTAACAGGTTAATATCAACAAGCATGACTACACCTCTTTTAAAGCCAGTCCAAATGCAAGATAATGTGACCTTGGCAGCGGTTTATTTTTATCTGTTTGGAGCTCTTCGGCATCAAGGATCTCCACCTTGATCTCAAATCTAGTTTGTAGTTCCTTCATGATGTCATCTAACAAAGGATGATCACCTGTTAATAATATTTTAGAAATTTCATTCTTACCTTGATGTAATGAATATTGGTAGAACTCTATCAGCTTATTGACTTCCTTAAACGATTCATCAAATTGTTGATATAATTCATTCTTTTCGCCAATAAAGGTTAATTGTTGAAATCCACTGCGTCCAATCTGGATGTCCCAGTCTTTTTCCTCAAAAGGAATATACATATGGCGAATAAAAAAGGGAATCTCATTTTCAAAAATACTCATAACCACGAGGTCCAAATCAAACTGAAGCACAAACAGCTTCTCCTCTTGTTTCGGTTTCCTTAATTGGTGATAAAGACGATAAAGAGCAAGAGAAGACAGATCAGCCACCTCTGGGATTAACTTTAAGCTTGAGAATAGATCGGTAAATTGCATTACATAGCGCTGATGGGCCGCAAACAGAAGGATTTCCTTCTTTTCCTCCTGTACAGGTAGAACGATATAATCAAAAACTGGATCTTCGAACGGTAAGTGAATACTTGAACCAATTTCTAAATAAAGGTACCCCTTAATTTCATCATAGGTAACATCTGAGGGAATGGTGATCCTCCGAATTGTCACATAAGAATCTGGGGCTAAAAAGCGGACTTTTCGTCGCCGAATTTTCCAAATATCAATACATTCATCAAGAATGATCTTCAAGGTATCTGGATCAATGATTTTACCTTCCTTGACTACACCCGGAGGCAAATACCTTTCCCCCCACTTAATTGGAAGCGGAGGGTTAGATGGTTTCATTTCAAGATAACGAATCGAATGATCATTAATAATGATATCAATCGGCCTATTACTAACCGAGATGAGGGGTAAAGCCATGTGTCGACCCCCTAGCTTTATGAGAAAAATAAGTTAAAATACGCTTGAATGATCTTATCACCATAATAATAGGCAACGAGCGTTCCAGCGCCAATAAACGGGCCGAACGGAATCGGCTTTCCTTTTTCGAAAATCCGTACAGCCATTCCAGCTCCACCAATTATAGCACCAAACAAGGTTGATAAAAAAAATGCTAGTAATAAGATTTTGACCCCTACAACAAAGCCGATAAGAGCGAATAGTTTAATGTCTCCACCGCCCATACCACCTTTACTAACAAGCGCAATCGCTAAAAGAACAACAAAGCCAATTGCCGCTCCAAGTAATGAGTCCCACCATGGCAAAAGTGGAAAGAAAAGGCGTTCCATTAAAAAAATCCCTGCAAATACAAGCAAAACTTTATCAGGGATCAACATATACGCAACATCTGATACTAGAATAATAATAAACAGTGAAATCAGTGTCAAGGCAATCAGCAGCTCACTGCCCCAGCCAACGACTAATGGAGCGGTTGCAAACAACACTCCGGTAAAAAGCTCAATGATAGGATAAATGGGCGAAATGCCCGTTTTACAGACACGGCATTTCCCCCCTTGAAATAAATATGATAAAACTGGTATTAGTTCGAAAGCTCTAAGTTGATGCCCGCATGTTGGACATGCTGAGCGTGGTGAAACGATTGACTGCCCTACTGGCACTCGGAGGCCGACTACGTTGTAGAAGGAGCCGAATAATATCCCGTATATGAATAGTAGTAAATATAACAAGGGTTAGCTCCCGTAAATCTTATTTTTACTGTCCATTTCCAATTGTTGTTTCAGTTTTTGACGCGCTATTTATGTCAGCTACAGTGGCATAATCGAATGTTAAATCTCCACCAGTAGCCTTTATGGAAATTTCAGTGCCTCCAGTAGCTGTCGTATCTACATAGAGTTCAGTTATTGTTATGTTAGAATTTTTATTATCCAGATAAGTTTTTAATTCTTCCGCAGTTATGGTTTTATCAGTAGGAATCCCTTCTGATGCAATGAATAACCTGCCAGCATCAATAGCTTGGATTGCAGATGATTTTACTGCATCATTTCTTGATTTATCAATAATATTTCCAATAGCCGGAATCGCAATTGCTGCAATTATCCCCAAAATAACGATAACTGCAAGTAACTCGATTAATGTAAAACCTTTATGATTTTTAAGACGTTTTTTTAACTTTTGTAGCATACTCTCTCACTCCTTTTATTAAAGATAATGGTGTTAATTTTTATAGCCTAACCATTTCATTATACAAGGAAATTTCACAAAGGAATAATGAAGATTTTACAACATTCTACATTTTATCGACATTTTTGAACATGTCAAACATCGGCATCATGATCGAAAGAACAATCACCCCGACAATACTAGCTAAAAAAACAATCATTAACGGCTCAATAAGCGATTTTAGCTTTTCCGTACTATTCTCAACTTCTTGTTCATAGAATTCAGCAACCTTGAAAAGCATGGAATCTAAAGAGCCTGTGTTCTCGCCAATTGCGATCATTTGCGTGATTAATGGGGGAAATGCCCAGTGTTTGAGCATCGGTCCGGTCATCGAATTTCCTTTCGCTAATTCATCTTTTGAGGCGCGAAGGACCTTGCCAATTACTTCATTTTCAACAACATTTTCGACAATTGAGAGAGCTTGCATAATGGGCACCCCGCTTGAAAATAGGGAGCTTAATGTACGCGTGACCCTAGCTAAGGCTGCCTTTTGTAACATTTTTCCAAATAATGGCATCCTTAATGATACATAATCAAAATAATATTTTGTTTTTTTGTTCCGTTTCACTCCGACAAATCCAATGGCAATTAAAATTACAAATAATATGACAACCCACCAAAATGATTGCATGAATTCACTGGCATTTAAAACAAACTTCGTAATGGCCGGAAGATCTGCCCCCATATCAGCAAACATGCTTACAAAGGTAGGGACAACTGATGTTAATAAGAAGATAACAACCCCAATTGCCACAATTCCAATTACAATTGGATAGGAAAGCGCAGACTTTATTTTTTGCCGGGTGGTGTGTTGTTTCTCAAAGAAAACAGCAAGTCTTTCTAGCGTCTCCTCCATATTCCCCCCTGCTTCACCAGCTTTTACGAGATTAATAAACATCGAAGTGAACATTTTCTTGTGTTTTTCGGCCGCTTCGGAAAACGGATTTCCTTTACGCAATTCATTTTCAATGTCAATCAAGGCTGCCCGCAGCTTTTTGCTTTCCGTTTGCTGGGCGAGAATATTCGTTGCCTCGACAATGGTTACTCCTGCTTTAATAAGAGTTGCAAATTGCCGTAAATAAATAACCATATGCTGAAGTTTAACAGGTGTGCCAAAAGAAATACTTTTATTTAAACCTGCATCTTTTACTTCAGTCAAATCGAGGACCCGTATGCCGTCCTCACGAAGTTTATCAATGGCTTCACGTTTTGAATCTGCGTTAATGGTTCCCGCCTTTTTTCCTTTGCGATCTCGGCCTGAATATTTATAGCGCGCCATTTTAGTTCACCGGTCCCTTTAAATATGGGTCGGCAACTTCTTGGGCAATGACTCCCGTTTCCAGCAACTCTTTAATGCTCATTTCTAACGTTTGCATCCCTTGTGACCGAGACGTCTGCATGGTCGACTCAATTTGGTGGATTTTATCATTTCGAATTAAGTTTGCAATCGCTGCATTATTGATTAATATTTCTAGTGCAGCTCTTCGGCCTTTTCCGTCTGCCGTTTTAAACAGTCGCTGTGAAATAATCGATAGTAATACCGATGCAAGCTGGGTACGGACTTGGGGCTGCTGGGCTGGCTCGAATACATCAATCATTCGTTCCACTGAAGCAGGTGCGCTAGATGTATGGAGCGTTCCAAACACTAAGTGGCCTGTTTCAGCAGCGGTGATGGCAATTTGAATCGTTTCAAAGTCACGCATCTCTCCAACTAGAATCGCATCTGGATCCTGGCGGAGTGCTGCCCGTAAGGCATTCCCAAAGTTCTTCGTATCAAAGCCAATTTCGCGCTGGTCGATAATTGACATGCCATGTTTGTGCAAATATTCAATCGGGTCCTCTAGCGTAATAATGTGCTCGTGCATCGTTTGGTTCATATAATTGATCATCGCCGCTAACGTCGTTGACTTACCACTTCCGGTTGGTCCTGTCACGAGGATTAAACCTTGTTTCTTCTCGACAATTCTCCGTAGCGTATCAGGAAGATTTAACTCATCAATAGTCGGAATACGAGTCGGAACCGTCCGGATCGCCAAGGCCACACAGCCTCTTTGCTTGAATATATTGACACGGTACCGTGATACATTAGGAATCGAATAGGAAAAGTCCAACTCCCCCATTTCTTCAAATACCCCCCACTTTCCATCTGGGGTAATCGCCCTTGCCATCGCTTCGGTATCCTCGGGCTTGAGAACTTCTTTTCCATAGCGCTTCAATTCACCATGGATTCGAAAAATGGGTTGTACAGATACTGTTAAATGGATATCTGATGCCTTTAGCTCAAAGGCTGCTCGTAATAATAGATCGATTCTTTCCCTCACCAGTTTGCACCTCTATTCAGAAATGGCCACTCTTAATACCTCTTCTGTTGTTGTTAGACCTTGTTTCACTTTCAATAAGCCATCATCTATCAAGAAAATGGTTTTATTTTTAACGGCAATTTGCCGAAGATTAGCAACCGAACCACTATTCATAATGACATGACGCATTTCCTCATTAACCACGATTACTTCATGAATCGCGATCCTACCCCGATAACCAGTCATATTACAAGAAACGCATCCTTTACCGCGCATAATCTTGTCAATTTTTAAGCCTCGATTGGCAAAGATTTCAATCTCGCGGTTGGTCGCATCATGCGGTTCGCCACAGTCTCGACAAACTTTCCGAATAAGGCGCTGGGCGACGATACCAGATAATGACGTTGCCACCAAAAAGGGTTCCATTCCCATGTCAATCAAGCGTGTAACCGAGCTTAGGGCATCATTTGTATGCAGGGTACTTAACACTAAGTGCCCAGTTAATGAGGCACGAATTCCCACTTCGGCGGTTTCTTTGTCGCGGATTTCCCCGACCATAATAATATTCGGGTCCTGACGTAAAATAGATCTAAGTCCTGTGGCAAACGTCATGCCAACGTTCTGATTGACCTGAATTTGACTGATTCCCTCTAGTTGAAACTCCACCGGATCTTCTATCGTGATAATATTGACCGTTTCGTTGTTAAGATTATTTAATGCAGCATAAAGAGTTGAGGATTTACCAGATCCGGTTGGCCCAGTGATCAGCACAATCCCATTCGGCCTTTCAATCATTCGTAAAAAACGTGTTAAATTTACCTTATTAAAGCCAATCTTATCGATATCAATCAGGGCGTTACTTAAATCGAGAATCCGGAGTACAATTTTTTCTCCAAACACAGTCGGTAAGGTGGATACCCGCAAATCAATTGGGTAAAAATTAAGATTGATTTTGATGCGTCCATCCTGCGGGATCCGGTGTTCGGTAATATCCAAATTGGCCATAATTTTAATTCTCGCTGTCAGAAAGCTTTGCATATTTTTCGGTAGGACTCGCTCAACCCGTAACAACCCATCAATACGATATCTAACAACAAGCTTCGTTTCTTGGGGGTCAAAATGGATATCGCTTGCCTTATGGGCAACAGCATTAGCGAGGATTTGGTTGACAAGGCGAACAATCGGAGAATCCTCATCTGTTATTGTCTCTTCCTGTGGATTATCCCCTTTTTTCATCCCATCAAGGAGATCATCAAACTCATTGTCCATGTCGTAAAATTTATTGATGGCACGAACGATATCATCTTTTGTGGATATAACCGCTTCGATTTGAAACCCTGTTGAAAGGCGCAAGTCATCAATTGAAAAGAAATCCATCGGATCCGCCATTGCTACCAACAGCTTATCCCCGTCCCTTCGTAACGGAATTAATAGATTTCGCATTGCTGCTTCTTTTGAGACAAGCGAAAATAAATTCGTTTCAAACGGGTAGTTGTAGAGGCTGAGATGCGGAATTCCAAGCTGAACCTCGAGAACCTCAATGAGTTGTTGCTCGGTAAGATAACCCTTTTGTAACAACGCATCTCCAAGCTTTTGACCTGGCGTTTTTTCGGATAAAGTTAACTGGAGCTGTTCCTCTGTAATCAGTCCAGCTTCCACTAATAAATCACCTAGTCGTTTTCGAGTATATTTCATAACGGATCACCGCTTTGACGTTTTTTTATTTCATTGTTTCATTTTCCTTCCCATACAAATCACTTTCCAAAGTAGATTGCTGGGTTGATGCCGTTCCATCCTTATTATTCGTGTATTGGGTGGTATTTTGCCCTGAATCTACGGTTGCTTGGCTCGTATCTGTTTGTCCATCAGAACTTTCACTTGTTTTCGAAGAGGTCAAAGCGTGAAGTTCGATCCGTGGAACAGGTGGATAAAAATCCTCTGAAATGGCCTCTTTGCGGATCCAAGCCCCATTTTCATCGTAAATTTCCCGGTAAACCTTTATAAGGAAACCATTTGCGCCTTCCTGTTGGACCTTTGTTCCATTGGCTGGTAGGAGCGGACTGTACTGAATAATTGTTTTCGGTTTAAATTCCTGCTTCTCCGCAATGTTTATTTTATAGTCGAAAAGGAACTTACTTCCGTTAAGAGTTGCAGTTAGTGTGTTATCCTGCCTTTGAAGCTGAATTTCATAACTTGCATCGTTTGGATTGACAAAGACAAGGTCGAGATGGGTGTCCAAGTCTACCTTTGCTTCCATTCCAAGACTGGCATATTCCGGTAAAACTACCCCAGTTTGTCTTTCGACAATCGTGAAGTTGCTGGATAAGATTGCTTCGTAAATAGTGGTAGCTAGCATACTGGCTGCTTCTGGAGAAAACGTTGCAAGCTTTTGAGCCTCGATTAATTTTAATAACGAGACTTGAGAATAGCCCTCTATTTTAATCGGTGACAATCTCTCAACCAATATCCCTAATTCAAGCGGAGTATAATCACATGTAATTGTTGCTTCACTTAAGACTTCGTTTTTATTGAAGTCTTTTGGTAAAAACTTTTCGACTGAAAGCTGGTATTCCCTGGCACTAAGATTGGTAGAATATGATATAAGTTCCGTAAGGATTGGATCGATAATAAGCTTTGGATCCTCAAGCTCCTTAGAAGCATTTTTTAACAATTCTCTCAGATCACTAGATTTGAACGTGACGATTACTTCATTTTGTTGTCCATCCTTTGCAGTCGCAACGGAGTTTTCTAAATCAATTTGAAACTTGCCCACATCTACTGGAATCGTCTTTTCTTTATATTGGAGGCTAATCTTTGTTTCGGAACGCCATTTTTGGAGCGGTGCACTTAAAAGTTTTAAGGCATCGGATTTGGTTTTACCTGAAACATCAATCGGACCAATCTTCGTACCTGTTGCAAACTCGTCACTAGTCGAAGTCATTGATTCGTAAGCCAAAGCGCCGAAATGTGAGAAACTATAAATAAATGCAGTGCACAAAAATAGGACAATAAACAGTTTTATACTTTTACCATTCCTCACATTACCCACCCCCTTACTATCAGGCTCGATTAATTTCAATTTTAACTTTTATGGTTTCCTTACCTTTTTTCGATAAGTACCTGCTCTTTTGGTGTTTGATTCGTGGTAGTTCGCTGAATTCTTTGATTTGCAAAGACCATCTCCTCAAGTTCATACTCTGGTTCTTTGACTGCCTTTTGTTCCTGAACTACGTTGCCATTTATTTCTTTTATCAAATCTTCAAGTGATAGTTCTTCAATCTCTACTTCAAAATCATTGGATGGTGCTGGAGCATCTTCACTGATTTCCTCTTTTGGAGCTTTTGGATTTGAAATGACTTCCAAACTATCATCTGTTTGTGGGGTCTGGATTGCTATTTCTTCCAATGGTTGAATGGAGTCTGATCCTAGTTCGTCACTTTCAATCATTTTTTCAATTTCTGACATGTAATCATGTGATTGTTCGATTATTATTGAGGAAGGTTCTTGTTGTTCGAGAGGCTCATCGCCCTCCTCTAGTAACGTTTCAAGATCAAACACCAAATCATCAGTTGTTTCAGAAATAGATGATTTTGGTTCTAACATTTCAATAGAATCTATTCGATAATCCTCAAGCTTGGAGTCCGAAGTATCGGCAAACCCTGGTTCTTGAAGTTCAGGTTCAACGAAATCAATATCAAGCACGTCCAACTCTACGTTCTCGACTAGGGCAAGATTCCCTTTAGCGGAAGTTAAATCCTCAATGCCTACTGGTTTCTTAAGTTTGATTCGATCTTCCTCATCCAACACTATCTCCTCGATTTCAGTGTCATCGAGATTGTCTTCATCGGGTTTTCTGATGAGTGAAAGTTCATGGTCATTTTGAAAGACAAGTTTCTCTAACAAAGTGGTTGGTACAGGCTTTTGAATGACTGCTGCTGCAATTTGGTTCTCAGCAGTATGTTGGATAACTTCTGAATCTTTACTTTTAAGTGTTTTTTGCTTTTTAGCAAATTTTTTGTCTCTTTTATCTAATTCCACTTTTTTATCGGAAGATGCAATATAAGAATAATTATCATTGATGACCACTTCTTCGGCAGGAGAATCCGGTTGTTGTTCCTCTTTAAAAAATGGATCCTGGTTTACTTCGGGAAGATAAAGCCATTTCCCCCCCTTTTTATTGATAAAATAACTAGATGTGCCGACAAACATTAATAGGATCCAGCCAGTTTGCCATAGTGAGAATACAATGGATGCTACCAAACCAAACAGTCCAATCAAAAACGAAGCCACAGCAAGTAAGACTTTCCCTTTTACGGTAAAGCCTATTGGTAAAAAATAAAGTATTGGAAAAAGGATGAGTAATGAAACTCCTGCAAATAGTAAACTCTCCATTTTTCCACCCCTAACTAGGAATCTAAATTTTTTTTATATGTGAAATCAACAATTTTATACAATATACGACTTTCTCATATTGTATAATATCAAATACTATTTTAAAAGAATATCATTAAAGGATTATAGGCAAAATAGATTAATTAAAAGGTTTTTCTACCAGATGTTCATAGAACCCCCTTATAATCGATAATAAAAAAAGTGTACGAAGGTTCGCACACTTTTCCATTATACTATTCAACGATTCACTTCTATTTATTGCTCGCGAACTGGTTCCCCGGTGATCGTGTCTTTTACCGGAGATAGTCCCGTACCATTATCTACAAATAGCGGGGAATTGTCATAGTTTATTTGAACGAATTTGAAGATAAAACTATCATCGTTCCCTTGTGATGATAAAGATTTAGCAATAATCGAACCTGCAAACGAAGCATTAATATTGACAGTTGCATTAGGAGCAAAGATCATTTTGGGGTAGTTAGCTGTTCCGGAACCAACAATCGAAATACTCGTCCCACTCGTTACAATGTGGCCTTGAACACCGGATACAAAATTGTTAACCACCAAATTGGAATTTTTGGCATACATTGACGCATTAATAAGTCCATATATATTCGAGGCTGTCCCTTCTAAAAAAATATAAACCTTTTCGAAATCGCCGCCTGTATTCAAGATACTTCCAGATGTCATCGAAATATTTTTAGCATAAATAGAAAGCTTTGCACTTCCAACGATTTGAATTTTCGCCCCGCTCAAAAGTGTAAGATTATTAACGACTAAGTTCTTGTTTATATAACCAACATCAATCGTTAACGTTTGGTTGGCATTTACAGTAAGGTTATTTAATACCATATCTTGGTCCATCTTCAATGTAGTGTCTGTAAAATTAGCTGCATTTGTGGGAATAGTAAAAAGAGGAAACTCAGGAATATTTAATTGTGTCCCAACATTCGTATAAATATTACCTGTAACAATTGCTTTGCTTCCGTTTAAAGTAATATCTGTAGCAGTTCCATTTGTACCAATTGACCCATCGACCGGAACGTTTTTTAAAGTAAGATTTTCTTGTACAAATAATACCGTATCTGCTGGAATCGTTACACCGCTTTTGGGTTTCCAAGTAAGGTGAATGATTTTCACTACAGTCCTAGAACGATTATTGATGGTGCCGGTTGAGGTGATTTTATAATTATTGCTATAGGAAACAACCGTTCCATCCTGTAATTTCTCGATTTTTATTTTAACAACAGGATTTCCACCAAACGACTCTTCGAATAAATTTTCAACTGTTTTTTCCTGACCTAATTCCATTAAATTATCCACACTAGAAAAAAAATCAGTATAGGATAACGATTGGCCATAAATGGTACTAAGCTTGGTCCTAATATCATTCATTTTATAGGTAATGCCTGATTCAGCAATGTAATAGGATGATTGATTATTCCGTTCCCCAGAGGTCATTTTTATATTGCTTGCCGCAAGACCCATAAGACTGAATCCCATGATGGAGATGACCACAAAAACTAGTAGTACTGTAACTAAGGCTACACCGTTTTCATTGTTTAATGATTTTATTTTGGAATACCAATTTTTCATTGACATCACCTATTTTCTTAAATAGATAGTTGCTGATAGTGTTGTTTTGGGTTGATTATTTGATGGGGTATTGGTAATTGTGATGGTCACTTTATCTTCTGTTTTCGTAATGGTGAATGATTGTATATTTGAAATTAACGGTTCGTTATTTTTTTTAAGAATATTATTTTCAAGTTTGTATATATCGGTATTGTTAATCGTTAAAACATTATTTGTCACACTTACATTTGAAGCCTTCCTAATTTCCTTTGTAACTATATTTAACGCCAGTCTGACATTGGATTGATTCTGAATTTCATTTGTTTGGTTATTCACTTGTTTTTGACCAAATAATTGAACAGAACTTGCCAGCAGTATCACCATTGAGACCAAAGCAAGTGCCGCTAATAATTCTATTAAGGTTATTCCTTTTTCATTTTTTTTAATAAAGCCTACAAATTTTTCCATGATAGTAATATCTCCATTTGCGCCTCTTTTTTTGTCTTTGTATTATCTTTGAAAACCTTAACCCGAACCTTCACTAGTGAACTATTAATGGTTGGTACTAACTCAATCGATACATAATGTCCGGTGACATTCTTTTGGTAAAAAGCATTAGTAGTCGTCTTGCTTGCTTGGGTATATCCCTTACTTACGATTGCAGCAGTAGCGATGTCGTAACTGGTGGATGCAACCACGATATTGTATATTTCCTCCATATTAGTTTCTGCGATATAGGTGGCATCCATAATATTCTTCGACATTGCATTAGTACGGGATGATTGAACGAACATGGCTATGAGTGACACAATAATGATTGATAGGATCACCATCGATGCTAAAATTTCAATCAAAGTAATCCCTTTTTCAGAGGAGAAATAACAAGTAATTTTCTTCATGTAAATCATCACCCCTAGATTGCTTCATACTAATACCATTATATATATTTCTAGTTTTATCGACATATTTTTTAGTTTAACAGGCAGATAGATTCATTACAATCTTAAGGTGATACCGCGAAAAGGATCCTATTTTAGACTTTTAATAAAGAAGGATTTTCTAGAATGATAAATTCTGTTTCAAAATAAAAAGCGGATCTAACCCACAATTAGTGAAGTTTATCCGCTTTTTATTTATTTTATAAGATTAACTAGGAACGGCTTTACCTCCGATAGGAAATAGAGTGACCCAGTAATGACTAGGATTTCATTTTCCTTTAAGGTTGGTATTGTCGTTCTTAAGTACTGCTTCCAATCTTTGGCTTTATGTTTATTTTGTGAACAACTTAGTTCATATAAGAATTGTGCCTGTGAGGCACGGGGGTAAGCGAATTCAGTAAAGGTAATACTGTCAGCAACGGCATCCAATTGTTGAATCATCTTGTCCAATTTTTTATCGGATAGGGCAGTAAATAAAATCTGGATTTGTTTGTCGTTGTACCGTGCCTTTAATTCATGCACTAGGGCCTCAATTCCTTCTTCATTGTGTGCCCCGTCCATAATGATGGTCGGCTCCTCTAAAATCAATTCCAGTCTGCCTGGCCAATAGGCACGTTTTAGTCCTTGAAGGATATGAGGTTCATCAATTAGCAAAGCATAGAATTGTTTTAATAGCTGTGCCGCCATGATGGCAAGTGCTGCGTTCTCGGTTTGATGCTTCCCTAGCATAGATATTTGTATCTGTGGCAATTCTTGAAAAATGGAGGAGAAATTGAACTCCTCGCCGCGCATTAACGAATGATTGCCGGAAATGGAAAACTCTGAACCAAGCTGGTATAAAGGTGCCTTTGATTCCATTGCTTTTGCTGCAATAACTTCCATTGCTTCGTCTTGTTTTACAGCTGTTAAGATTGCCGTCCCGTTTTTTATAATCCCCGCTTTTTCAGCTGCTATTTTTTCATATGTATCACCAAGAATATTGGTGTGGTCCAAGCCAATACTGGTGATAATCGATAATAGCGGGTGAATGATATTGGTTGAATCAAAGCGGCCACCCAATCCTACTTCGAAAAGAGCCACATCAACAGGATTTATTTTTGCAAAATAATACAGTGCCATCGCTGTTATCACTTCAAATTCAGTTGGTCCGCCTAGTTCGGAGTGATCCAACTCATCCGCTAATGGAAGAATCACATTTGCAAGCTCCAGCATTTCAGCATCAGTTATTGGCTTTCCATTCACACTAATCCGCTCATTAAAATGCTCAAAAAACGGAGAAGTGAAGGTTCCAACCTCGTAACCTGCTTCCTCCAAAATACATCGTAAAAAAGTCAGGGTTGACCCTTTTCCGTTCGTTCCACCAATGTGGATTGTTTTGATTTTTTGTTCAGGATGGTTGAGTCGCTCCATCATCCACTCCATCCGCTTCAAACCTGGCTTAATTCCGAGTCGAAGTCGGCCGTGGATCCAAGATAAAGCCTCATCGTATGTTTGAAACACTGTTTTCACCTCCAAAATTGCTGCTACCCACTAAATTTACGGTTCTATCCGCCAAAATCCAGCCTCAATCCGCGAAAAATACACGCCAATCCGCCAACCTATGTTTTCCGCATAAATCAATCATTCTACAACAGGAAAGAACCCGAAAAAACGGGTTCCCCTCACACTTTACTTTTTATAAAATTCAATCGCAGCTAGCAGTAGCTACAACAATTATAAACTTTTTAACTCATTCAAACGAACTTGAACCGCTGCACGTTTCTCAATGTAATCCTGCTCTTTGGCACGCTCTTCTTCGATTACCTTTGCTGGTGCTTTTTTAACGAAGCCTTCGTTGCCAAGTTTCTTCTGAACCCGCTCTACTTCTTTATTCAGACGCTCAACCTCTTTTTCAAGACGAGCTCTTTCTTCATCCAGATTAATCAAACCAGCTAATGGAAGAATAATCTCAGCTCCCGTAACAACCGCTGTCATCGCTTTATCTGGGGCTTCCACCTCAACAGCGATCACGAGCTCCTCTGGATTACAGAAACGCTCAATATAGCCACGATTCTTCTCTAGCACAGCAAGAACGCCAGCATCCTTCGCCTTCAGGATCATCTTAATTTTTTTGCTAAGCGGTGTATTCACCTCGGCACGACTATTTCGAACAGAACGAATGATTTCAACCAGCAACTTCATCTCACCAGCAGCTTGATCATCAACCAACGCCGCATCAACCACAGGCCAGCTTGCCGTTGTAATCGACTCTCCAGAATGAGGCAGGTTTTGCCAAATTTCTTCCGTGATAAATGGCATGAACGGATGTAACAAACGCATCGTTTGATCCAATACATAAGCTAAAATGGAACGAGTGGTTTTCTTCGCCGCTTCATCGTCACCGTATAAAGGTAACTTCGCCATTTCGATATACCAATCACAGAAATCGTCCCAAATGAAGTTATAAAGCGCCCGACCCGCTTCACCAAATTCGTAGCGATCAGACAAGCGCGTAACATTTTCAATCGTTTCGTTTAAGCGAGTTAAAATCCACTTATCAGCAACCGACTTTTCCCCACTCAAATCGATCTCTTCAAATGTCATACCGTCCATATTCATCAATGCAAAGCGGGATGCATTCCAAATTTTATTAGCAAAATTCCAAGTTGCTTCAACCTTCTCAACACTAAATCGTAAATCTTGACCAGGTGAACTACCAGTTGATAAAAAGTAGCGCAGTGAATCCGCCCCATATTGATCGATGACTTCCATCGGATCAACCCCGTTACCAAGCGATTTACTCATCTTGCGGCCTTGTGCATCACGAACAAGTCCATGAATTAATACATCATTAAACGGCCGTCCCCCCGTGAATTCAATCCCTTGGAAAATCATCCGTGATACCCAGAAGAATATGATGTCGTATCCTGTTACCAAACAAGCAGTTGGATAATAACGCTTAAAGTCAGCTGAATCCTTATCTGGCCAGCCTAAAGTCGAAAACGGCCATAACGCTGACGAGAACCATGTGTCTAAAACATCATTGTCCTGAACCCAGTTTTCGATATCAGCTGGTGGCTCGTTCTCTACGTAAATCTCACCCGTTTCTTTATGATACCAAGCCGGAATCCGGTGGCCCCACCAAAGCTGACGTGAAATACACCAGTCACGGATATTCTCCATCCAATGCAAATACGTCTTTTCAAAGCGATCCGGAACAAAGTTAACCTTATCTTCTTCACTTTGAAGTGCTACAGCAGCATCAGCTAACGGCTGCATTTTAACAAACCATTGAGTTGAAAGGTAAGGCTCAACAACCGCCCCACTGCGCTCAGAATGCCCTACTGAATGCAGGTGATCTTCAATTTTAAACAAAACACCTTGTTCCTGAAGATCCTTAACGATTTGCTTGCGACACTCAAAGCGATCCATTCCTTGATACTGTCCAGCTCGAGCATTCATCGATCCATCTTCATTCATAACAAGGATTCTTTCAAGATTATGGCGATTCCCTAATTCAAAGTCATTAGGGTCATGTGCTGGTGTAATTTTCACAGCACCAGAACCAAAGTCCATATCAACATAATCATCGCCAACGATTGGAATCTCGCGACCGACAATCGGCAATATAACCGTCTTACCAATCATATGTTTATAACGCTCATCTTCAGGATGAACCGCAACGGCTGTATCGCCCAACATCGTTTCCGGACGGGTCGTTGCCACTTCAATATAGCCTGAACCATCAGCAAACGGGTACTTCATATGATAAAACGCGCCCTGTACGTCTTTATAAATAACTTCAATATCCGATAACGCCGTTTTCGTTGATGGATCCCAGTTAATAATATATTCACCACGGTAGATTAAATCTTTTTTGTAAAGACTCACAAATACCTCTTTAACAGCATCTGACAGCCCTTCATCAAGAGTGAACCGTTCGCGGCTATAATCTAACCCAAGACCAACTTTTGCCCACTGCTGGCGAATATGGCCAGCATATTCTTCCTTCCATTTCCACGTTTCCTCAACAAACTTATCACGACCAAGATCATAACGCGTTTTCCCCTCACCACGAAGCTTTTCCTCAACCTTCGCTTGCGTAGCAATTCCGGCATGGTCCATCCCAGGCAACCACAAAACATCGTAACCCTGCATCCGCTTCATTCTAGTCAAAATATCCTGAAGCGTCGTATCCCACGCATGCCCTAAATGTAGCTTTCCCGTTACATTTGGCGGCGGAATCACAATCGTATAAGGCTGTTTCGTTTCATCATCCTTAGCCTCAAAAAACTTACCCTTTAGCCACCAATCATATCGACCCTGTTCAATCGCCTGCGGATCATACTTCGTCGGCATTGAAATCTCCTTCGTATCCATAATCAAACCTCCATTTTTTTAAAAATAAATCAGCTTCGTTTGACAGCTAGTCTCCCGACACACCTCAATCAAATTCGTTCCAAAACAAAAAACTCCATTCGCCATGAAAAGGACGAATGGAGTAAGCTTCGCGGTACCACCTTTTTTCCAATTAGAAAAAGACCTAATTGGCACTTGCTTAGATAACGGATTTTCCGTCTCCGGCTACTAGTTAACCGTTCGCAGGAGATGCTCAAGGGCGACCTTCCAATGGTCTGTATAGGAAGCTTTTCAGCTAATAGCTTCCCTCTCTACAAACAGATAACACTGTACTCTTCCCTATCTTCGCTATTATTTTCAATTGTATCCCATACATATGGGTTAGTTTACTTTATTCTATAAGCTATACTACCTAAAAAAGGGGAACATCGTCAATCATATTACCCAATTTTTTTGGTGGATATACATTTTTTTAAGGATCCTTTCACATATTTATAGCACTTTTACCTAGTGGAGGTCATATTATAGAACAAAAAGCTATTATAAGGAGGAAGAATGGTGAAGCGAAGATACAATCCTCACGCACTTCCGCCATGGCTCCGATATATTCGCGGTAGTTGTTGCCAGTTTATTATCCCGTTGTGTGTTTTCCAAGTCATCCGAACGATTATCCTGCCAACTACCTTCGATGCACTCCTGTTAACCATTTTGATATTACTCGCGTTGGCCTTTCAATTTGATATGATATGAAAAGCGAAAGCGCCTTGGTTATCCCCAACAAGCAAAAATCGAGCTCTTCAGGAAATCCCGATTTCCGGAGGGGATTGTCTTTTGACCTCGAGGGCTAGGTGCTGTTGCTAAACAATAAAAGGAGCCTTAAGTTGACGATTGTCAATCTTGGGCTCCTTCTTGTTGTTGCGCCTGTGCTAGTGCCTGCGCCTTCTGTTGTTCAATTTCCTCGAGTCGCATCACCACATACTCAGTATTTTTAAGCAACCAATACTTACGCTGCAGCTGTTGTGAAAATTTTCGTTCCTTTTTTCCTGGTTGCTGTTTATGATATTTTTTCAGGACCTTGATGATGGCACTAGGATGGGAAAAATAGCTCAACATTAAATGCTTTTCCTCTTCTTTTAGTGGAAAATATTTATAATAAATAAGCAACCATTCAATACATTCCTCGCTTCTTTTTGGTAACCCCTTTAAAGTCTGATGTAAATAGGGAAGAATGTCTTGATAGGGAGAACCCTCCTTGATGTTTTCAAAATTCATAAAATATCCATAGCCTTTATCATCAAACAAGAAATGTTCAGGAGAAAACTTTCCGTGAATCAATACGGTCCTAACCTTCTCTAGGTCCTTTGTTTTCTCATACCATGCCTCAAGCCTACGTTTTGAATATTGAATGGCTTGTTTGACCTCATGATAATATAGACAAAATTGTAATTCAAACGGCGACATATATATTTTTTTTTCAGAGCTTTCAAGAAACCCCGTTATAAATTCTTCGTCTTTTTCCAACAAGAGCAATGTATTTTCATAATGTTCTTTTCGATCCTCTTTTTTTATTGGAACCTCACGAGACGATAGTGTATGAAGCCTAGCCAGTTCGCGAAATAATTTCTTATTTCTTTCTACTGGGTCCTCTTTCGCTTCATTCTCTAGCCAGGGCATTAAATAGTAAAGCATATTTTGGTGAAGGACTGCATAACGGCCATCCATTGCCGGGTAAATCGGGACAATTCGGTTATAGCCCTTTTGATATAGCGTTTGAATATGGCGTATAAATTCGGTGCCTAATTGCGGCGGTATCATTTTCAAGGCAAAAGCACCTTTGTTAGAGTAAACCTTTTGTATTTTTCCCAAGTCCTCAACATAATAAGGTTCAACCGCATAATGAGCTAAAATGGATGCTACCCCATTAAGATTGTTGTTAGCATTCACATGACTTCACTCTCTTTCGGACTGAATGCGATTTCTCCAAAATAGGAGAGCAGGCAAAAATCACCTGCTCATTCAATCCTTATCTACTATTTGCAGGCTCCGGAATATAAAGGACTTGCCCCTCGTATACATCCTGTGTGGCCTCTAAATGATTCACTTTTAATATTTGTTGCACACCAAGGGCATAACGTTCTGCCAAGCTATCAAGTGTTTCACCATGCTGAACAATGCAGACCTTTAATTTTGCTTGAAGTTCATTTTCTGTTTTCCTACCTAAAAATTCAGCGATTGACATACTTTTTTTCTTGGAGGACTTTTTCTTTTTTATTTGAATTTGTTCAGAAGATGATGAGGAGGATGACTCATCCAGTTCCACCTCAATCACCACAACAGTGTCATTACTTTCAGCACCAGGTTGTTCATAACTAGATTCTTGCGGATATTCTACTTCGGCTTTGGGAACCAACGGATCTTCTCGTTGAGATGCAAAGGAGAAATCTGGCCCCTTTGATATAGGTGGTTGATTCGATTGTATCGGGATTCCCCAGGCATAATCTGAGGGGGCAGTATTTGCATTAGGCTGTTTTTTTGCCTCAGCTGAAAAAGGCTGGGAAATTTCGTAAAGTCCTGATTCATCTTCTTCAAGTTCGTCTGACACCGTCTCATTTGGATATGAAAGAATAAAATTCGGATTGTAACCCTGAGTTTCTTCATACTCTTCAGTTTGACCTGCCCGATGTAATAACTGTAGTTCAGGTGTTTCCTCACCTTGATCAATCTCTAGAAATATTTCCTCAGCTTGCTCTAAATGATCTTCATTCACTACTTCCTCATTGTAAGACTGCACCTCTTCTGGCTCCCGCTGATCCTCTTCAGTCGGAACATTTTGCTGTTCACCGTAAAGACCTGATATGGTCAATTCAGCTGCGAGCCTTAGGCAACTACGCTCAGGTACTGCATAATCAAACGAATCTACGGTCACACCAATATCGTTTATGCTCTGAATGCGATTATTGGGGATTGTGATATCAACTGGAAACCGGTGCGTAAATTCACAAATTCCTTCTTCTCTTTCCTCAACAGACTGGATAAATTTAGGGGCGGAGATATCCTCCTCTGTTTCAAGTCCATCCTCTTTAATCCGCACGTATTCACCTGTAAGTTCAAGCGAACCACGGATAGCAACATACTGATCATTTTCGACAATAGTTATGTTTGGATCCAAAGATATCGAAACTAGCTCTGCGACTTCCTGTCCTCTTTGAAACCACACTGACTCTTCTAAGGAAAATCGTAAAAACGATTGATGCTCATGAGACAAAGCGACTTCCTCCCTTCTAAACCATTAACGTTAATCACTATGTCATTAACACTCTATGAATTAGAAGGGATTTTTATGATAAAAAAAACAGCCCGATTCCCCGCAAAAAGCGAGAATCAGGCTGTCTTTTATCCTTTAAGTTTTGAAAATGCCACTTCAGCAGCTTGAATTGTTTTTTGAATATCTTCATCACTATGTGCTGTAGATAAGAATATACCCTCAAATTGAGATGGCGGTAGGAAGACTCCTTGGTTCGCCATTTCACGGAAATAGTTAGCGAAAAATTCTAGATCAGACGTTTTGGCTGTATCATAATTAATCACGTTTTCATTCGTGAAGAAGAATCCAATCATTGAGCCAGCACGGTTACAGGTTAGCGGAACATCATATTTTTCAGCTAATGCTTTAAAACCCGATTCTAGCATATCCGCTTTGCGAACAAACTCTACATAGTTTTCTGGGCTTAATTGACTTAATGTCTCAAGTCCAGCTGTCATCGCTAATGGGTTACCTGACAATGTTCCTGCTTGATAAATCGGACCACTTGGAGCAATTTGCTCCATAATCTCTGCTTTACCACCAAAGGCACCAACAGGAAGTCCACCACCAATAACTTTTCCTAGGCAGGTTAAGTCAGGTGTGATTCCGAAGAATCCTTGTGCGCAATTGTAGCCAACGCGGAAACCAGTCATGACTTCATCGAAAATCAGCAAAGCACCAGCTTGGCTTGTGATTTCCCGTAATCCCTCTAAGAAGCCTGGTTGAGGTGGAACCACACCCATGTTCCCAGCCACAGGTTCAACGATGATACAAGCAATATCATCCCCAAATTGTTCAAACGCATATTTAACGCCTTCTAAGTCGTTATACGGTACGGTTATCGTGTTTTTGGCGACACCTTCTGGTACGCCAGGGCTGTCTGGTAAACCAAGAGTAGCAACACCTGAGCCCGCCTTAATTAATAAAGAATCTCCGTGACCGTGGTAACAGCCCTCGAATTTTAAAATTTTACTTCTGCCCGTATAGCCGCGGGCAAGACGCAAGGCACTCATTGTTGCTTCAGTTCCAGATGAAACCATGCGGATGATCTCAATTGAAGGTACACGTTCTCTAACGAGTTTAGCTAGTTCACTTTCGATTAGGGATGGCGCACCAAAGCTTGTACCAAGCTCAGCAACTTTTTTAATAGCTTCCACTACGCGGTCATTTGTGTGACCCAAAATAAGTGGTCCCCAAGATAATACGTAATCAATATATTCATTTCCATCGATATCATATATTTTCGAGCCTTTTCCTTTTGCCATGAAAATCGGGTCCATGTTAACCGATTTAAATGCACGAACAGGTGAGTTAACACCGCCTGGCATTAATGTTTTGGCTTCTTGGAATGCTGCAATTGATTTTTCATAAGAGCGCATGTTTGAATCTCCTTTTTCCATTTTTAGAAACCAGGTTTATTGTTCCTTTAAATACTTCGCTGCATCTTTTGCAAAATAAGTAATGATTAAGTCAGCACCAGCACGTTTCATACCTATTAGCATTTCCATAACGACGTTCTTTTCATCGATCCATCCATTTTGGGCAGCTGCTTTGACCATGGAATATTCCCCGCTGACATTATAAATGACTACTGGAAGATTAAAGTTATTTTTCACATCACGAACAATATCTAAATATGGCATACCAGGCTTCACAATCAAGAAGTCAGCACCTTCAATTACATCAGATTCTGCTTCACGGAATGCTTCTAAACGATTAGCAGGGTCCATTTGATACGCTTTACGATCCCCAAATTGAGGTGTGCTTTCAGCAGCTTCACGGAACGGTCCATAAAATGCTGAAGAGTATTTTACCGCATAAGACATGATTGGCACATCTTCGAAGCCAGCTTCGTCTAATCCAGCACGAATTGCTACGACAAATCCATCCATCATATTAGATGGGGCAATGATATCTGCTCCTGCTTTTGCTTGGCTTACTGCTGTTTGAACAAGCAGTTCAAGTGATGGATCATTTAGGACTGTGCCGTTTTCGATGACGCCGCAGTGACCATGGCTTGTGTATTCACATAAACATGTATCCGCTACAACAAGAACGTCTGGATAATGTTTTTTAATAAATCGTGTGCCTTCCTGAACGATTCCGTGATCATGGAAAGCTCCAGTCCCACATTCATCTTTTTCGGAAGGAATACCAAACAATAATACAGATTTTATCCCTAATGCCACAACTTCATCCATTTCGGCAGCAAGGTTATCAAGGGAAAGCTGAAATACTCCAGGCATAGTGGATATTTCATTTCGGATATTATTTCCTTCGATGACGAAAAGAGGATAGATAAAATCATTTACATTTAATTGATTTTCACGAACCAATGCCCGCATATTGGCAGTTGAACGTAAACGACGATGGCGCGTAAATTGTAATTTTTTCATGATAAAATAAACCTCCTGTTTATCTGGTAACTTGATTCAGGTTTTCTATAATCGCTTTGATCATATCCTTAACCGTATATTCGGTCGGAGAGACGTGAACCGTTAATCCGAGGGCTTTTGCCCTTTTTGTCGACACCGGCCCAATACAGGCTACTAAGCAAGATTTCAGTTTATCAGATAAGTTATATTCTTGAACAATTTCAATAAAATGATCTACTGTCGAAGGACTTGTAAAAGTTAAAATATCAAGCTCTTCATTTGATAACATCTCAGCTAATTCTTTTTTGCTCTCCTCTGGAGCGTATGTTTCATAGATGACCGACTCTGTGACAATCGCTCCATGCTCAGTTAACGCTAAAGCAATATAATCTCGGGCAAGGTTTCCCTTTGGAATCAATACCTTCATCCCAGGTTGAATGAGCGGCAAAAATTCACTAACAAAACCTTCAGCAACATATTCCGAAGGTGTAAAAGCTACAGGAATACCTCGTTCTTCTAGTACTTGTTTTGTTCTTGCACCAATCACAGCCACCTTTGGCAGAGTTTGGCTATTAACCATACTTAAAAAAGTATCAACTGTTACATTACTTGTGAAAATAATCCAGTCATATGTATGAAGCTTCGTAATCATTTCTTTTAGTTTATCATTTAGTTGGACAGGCCTAAAAGCTATTAGAGGGATTTCAATCGGAATTCCCCCATTTTTTTTCACCAAATCGGAAAAGGGCTTTGCTTGCCCTTTTCCCCTCGGGACTAACACCTTTTTATGATATAAGGGCAAGGATGAAGCGGTCATTCATTTTCAAGCTCCCGCTTAACCTGATCAATCAATGCCTTGCCACCTTTTTCTGTTAAACGGTCTGCAACAATATTTCCAACTTCTTCAGGATTATTTCCTGTCAATTGTTCTTTATAAATGATATTTCCATCAGGAGATGCAACAAGTCCAGTCATGACCACTTCGTCCTGGTCATTGATATAGGCGTACCCTGCGATTGGAACTTGACAGCCACCCTCCATTTTTTGTAGATAAGCACGTTCTGCTCGAACAGCACGGTCAGTATTTTTACAAGTGAATTGATCTAGTAAGTCTCGTAATTCTTTGTCAGCCTCGCGACACTCGATTGATAGCGCCCCTTGACCAACAGCAGGTACACATACTTCATCGTCAATAAACTCAGTAATTACTTCTTGCGCCCAGCCAAGACGGTATAGACCTGCTGCAGCTAAAATAATTGCATCGTATTCGCTATCTTCAAGTTTGTTCACTCTTGTATCAATATTTCCGCGAATCCATTTAATCTCTAAATCAGGACGTTTTGCTAATAGCTGTGCACTGCGGCGCAAGCTACTTGTCCCAATCACAGCCCCTTGCTTCAATTGATCGAATGGTATGTTTCCCTTCGAAATAATTACATCGCGGTGATCTTCACGTTTTGGAATACTTCCGATTACTAGGCCTTCCGGAAGAACTGCAGGCATGTCTTTCATACTATGGACAGCCATATCAATCTCTTTATCAAGCATAGCTTGCTCTATTTCTTTCACAAAAAGGCCCTTACCGCCTACTTTAGATAAAGTAACATCTAAAATACGGTCACCTTTAGTCACAATTTCTTTAACCTCAAATTCGAACGAACCACCCAATTTTTTTAATTGATCGATAACCCAGTTCGTTTGTGTTAACGCTAACTTGCTTCGTCTTGAACCAACAATAATTTTTCTCATGTCTGCCTCCTAGTGTCATGCGTACCAAAAATGAAATGATGATAGTTTTCCGAATAAGAAGAAGTTTAATAAAACAATTAAAAAGGCTGCTACGTTCCATAGAGCGAGCGACTTACCTTGTAACCCTTTTACAACACGTAAGTATAAATTAATACTGTACGTACATAACACGATAAATGAACCAATGACCTTTGCGTCGAAAATAGTCATATTTGGCACCTTAATAAAAGCCCATTGCATACCTAGAATTAGTCCTAAAAGAAGCATTGGCACCCCAATTACATTTAATACATATGAGAGGTGTTCGAGCCTTGATAAATCTGCAATCCTGAGAAGCCTTTTCCCCCATTTTTTCCGCTTCAATAAATCATATTGAATCAAATACAATAGGGAAAATACAAAGGATAAGGAAAACGCCCCATATGAAAGGATAGCCATTGTTATATGGATTAACAAAAGTTCTGAAACAAGCCGCTGAGCAATCACTTCGGAATTATATTGAACCGGCGCAAAAGTGTGAATCGCCATGATGACAAATCCAAGGATATTGGTGAAAAAGACAATAAAATCCATGCGAAGTAACCTATTGATCCCTAAGGATAAAGTGACCAATACCCAAGTATAAAAATAAAGTCCTTCGAACACCGATAGGATTGGGAACCTACCTGTTTTTACAACATAGATTAAGAAAAAGGTTGTTTGCAACCCCCACACAAATGCAAGTAACCAGAAGGCCACTTGATTAGCCTTCCGGTTATTGTGAAGAAAATCAATAAAATATAAAAGAACACTTAAGGCATACACAAGAACTGTTAGTTCGTGCAGCCGGGTCATATAAATGTCAAACATGGACAGAACCTCTCTTATGCTTGGAAGGAAGCCTGTGGTGCATGAATCATTTCCTGTCTCGATTCGGCCGCTTTATTTTTGAGTTGTTGTTTCTCAACTTGTTCCTCGATATTAAATATTTTAATAAATAATTCCAATGCTTGTGAGGCATTTTGCTCACCTGCAATCTCCTTGGCTTGGAGAATCGGATCCTTTAACATCTGGTTAATAATACTTTTTGTATGTTTATTGATTACTTTAATATCTCGATCAGATAGATGAGACAGCTTTCTTTCCATGCTGGTCATCGTTTCTGTTTGAATAACAAGAGCCTTTTCACGCAAAGCAGAAATAACCGGAACGACGCCAAGTAAATTTAGCCATTGTTTGAAATCAACAATTTCTTTTTCAATCATTAGCATGATTTTTTCAGCGGCCTTTTTACGCTCCTGAAGATTGGCTTCAACAATCCCTTCCAAATCATCAATATCGTATAAAAACACACTTTCCAAGTCAGCGATTTGCGGATCTATGTCACGCGGTACCGCGATATCTACCATAAATAACGGTTTGCCTTTGCGTAATTTCGTAATGTTTACCATCATCTCTTTTGTGATGACGAATTCTGTTGCTCCCGTTGAACTAATCAAAATATCTGCTTCTATTAAAGAAGTATGAAGCTCCTCAAGCGTTTTCGCTTCTCCATCAAAACGACTTGCCAATCCCTGTGCTTTTTCAAATGTCCGGTTAATGACCGTAACTTTGCTAGCCCCATTGGCATGGAGATTTTGAATAGCGAGCTCACCCATTTTTCCAGCACCGAAAACAAGAACATGCTTAGACATTAGAGTTCCAAATATTTTTTTTGCCAATTCGACGGCCGCATAGCTAACTGAAACGGCGTTAGCACCGATATCAGTTTCAGAATGTCCACGTTTTGCAATTGTAATTGCTTGTTTAAATAGTTGATTGAATACCGTACCTGTCGTATTTTCCTGTTGTGCCAATAAGAAACTTGACCGTACTTGTCCTAAAATTTGCGTTTCACCTAAAATCATTGAATTTAGGCCGCAAGCTACTTTGAACAAATGTTCAACTGCTCCATCTAGTTCATAGATAAATAGGTACGGAGAAAATTCGTCTTGCTCAAGACCAAACCACTCGGACAGGAATTCTTTAATATAATATCGGCCAGTATGGAGCTGATCAACGACCGCATATATTTCCGTACGGTTACAGGTAGAAATAATTATGTTTTCAAGGATGCTTTTTTTCGATCTCAATGTCTGCATTGCATTCCCAATGTTTGCCTCATTAAACGTCAACTTCTCACGTATTTCGACAGGGGCAGATTTATAATTAAGACCGACAACTATAATATGCATTTTCTAAATGACACCCCCACTAAAATTGCATATTCGCCTAACTCATTATAACATGTGTGTTTTTTTTATCTGCTAAAAAGATGTGAACAGAAACCGAAATTATAGTGATAATACTGGTCTAAACACCTCTTTTTCGAGGTCTGTTTATGCTCAAAAGTCTGTTTTGATAACGCTTTCCTTACCTTTAATCGATAAGAATTTTTTCTTTTAAAGAATTAATTTATAATTGCCTGTTGACCGATGGTGTCTAGAAAGGTACCTTAAATATATAAAAAATCGACATATACTTCCTTTTGTACAGTACCAAAAAAAAGAAAAATATACAAGTGAACCTTACTGGAAGTGGTGAATTTAATGAAAAATCAGCGGTATTTTTCCGGAATTATTTTTATAGGTTTTGGTGGTTATTTTCTCCTGCAACACACAAATATTGCATTCCTTCAACAATTTACTGGTTGGCCAACCTTGTTGATGATTGTTGGTCTGGCATTTTTATGGCAAGGGTATGTTGGGAGAGAGAGTGAATTAATTTTTCCAGGAGTGGTTTTATTCGGTTTTGGCCTACATTTTTATGTAACAACCAATTTACATATTTGGACAGACCAAATTGGTATTTTTATATTGATCCTCGCTCTAGCCTATATTCTCAAGTATCAGAAGACAGGAGTCGGACTGGTTCAAGGTATATTGTTCGCCATCCTCTCAGCCTTGCTTTTGTTTCAGGATAGCGTTATGGGCTGGTTTGGGACTGTTGAATCCAAAGTAACCTATATCTGGGACTTTTGGCCAATTTTCTTAATCCTCTTTGGGATCTATTTTTTAATGAAAAAGAAATAAGAAAAGAGGGCAGGATTGTATCTTTTCCCTCTAAGGCTTTCGAGAAACCCTCGACAGTCTATTATTTCACCCAAAACCTTTAGTGATTCACCGCGTTAATTTATAGAAATAAATATTAATATATAGGCAGCTCAATAGGTTTGTTGATTTCCGTTCCAGACGCTTCGCTTTCCGCGGGGCGGGCGGTGAGCCTCCTCGGCGCTAAAGCGCCTGCGGGGTCTCACCTGTCCCGCTGCTCCCGCAGGAGTCTTCGCGTCTTCCACTCCAATCAACAGGTGGTTCAATACAGACCTTCCACTCAACCAATAGTAAAAAAATAAGTGGTGGAGAACAAACGTCGTCAACAGTGGGTTTTTAGGCTTGAAATTCAAGGACACTCGTGGGAAAATGGGGCTCAAAGAGCTGTTATGATGCCATAATCAGAAGTGGCAAGGAAAAATGGGAAGAGTTACAATGCTAATCAATATCCGAAGCGTCTTCCGAATTAGTGGCGTATTAAAAACGTTTAGATTTGTTCGGACAACAACAATTTTTGTAAAAACAGCCTTTAGAATAGAAAAAATTGAGCTAAGCTTCGCAGACTTAATGGAGATGCATGGGCTTCGCTACTGCCGGTTACCGGGAATGAAGAATGTTAGTGAACAGCCTCTCCTTCCTGCAGCCTGCCAAAAAATAAAAAAATTGCAACACATTTAGCCAGGTGGATAAGTTGTGTTGCAATTCTTTTGGGTGACCCCCTTGTTGATTGGAGCGGAAGGTGCGAAGACTCCTGCGGGAGCAGCGGGACAGGTGAGACCCCGCAGGCGCTTTAGCGACGAGGAGGCTCACCGCCCGCCCCGCGGAAAGCGAAGCACCTGGAGCGGAGATCAACAAGTCCCATAGCATAGACAATTTTATATAAAAAACAGGCATTTAATGTTCTGACAAAATGAATATTGCTGAGAAAATAATCTTTTATGACAATCTAAGAGGGCAGGATTTAAAATCCCTGCCCTCTTTACTTATTTCATAAAACTTTCTAGCACGGCCCAAGCCTTCTCTTTACCGTAGCCTGTTTCGGATGAGAACATGACTAATAGATCACTTTCAAGCATGTTCAATGTTTCTTTAGTAATTCGTACATGTTTTTGCCACTTTGACTTTGGAATTTTATCCGCCTTTGTTGCAATGACAATGACAGGAATCTGATAATGCTTCAAAAAGTCATACATCAACACATCATCTTTGGATGGTGGATGCCTTAAATCAACAATTAATAAAACGGCTCTTAACTGCTCCCGCGAGGTGATGTAAATTTCAAGCATTTTTCCCCATGCTTCTCGTTCTGATTTCGATACTTTTGCATACCCATAACCAGGAACATCTACAAAGTGAAATTGCTCGTTGATTAAATAAAAGTTAAGGGTCTGCGTTTTTCCAGGTTTAGAAGATGTTCTTGCTAAGTTTTTGCGGTTCAGCATTTTGTTTATAAAAGATGACTTCCCCACATTGGAACGACCAGCCAGTGCAAACTCAGGCATTATTCCACCTGGGTATTGCTCTGGCTTTACCGCACTAATAATAATTTCTGCGTTATTTACTTTCATTTCCTTCTCCAATCAATGCATGCTTCAAAACTTGATCAATACTTGAAACAAGTACGAACTCAAGCTGTTCCCGAACACTTTCCGGTATATCCTCAATATCCTTCTCGTTATCCTTAGGAAGAATAATTTTTGTTAATCCGGCGCGATGAGCACTTAATGTTTTTTCTTTTAAGCCCCCGATTGGGAGCACCCGTCCTCTTAACGTAATCTCCCCAGTCATCCCAACCTCTCTTCTGATTGGTTTTCCGGTTAGAGCGGAAACAAGGGCAGTAGCAATCGTGATTCCTGCGGACGGACCATCCTTTGGAACGGCACCTTCAGGGACATGAATATGAATATCATGTTTTTCATGAAAATCTTCATCTATCCCAAGTTCCGTTGCCTTTGAACGCACATAGCTGAAAGCTGCTTGAGCAGATTCCTTCATGACGTCACCTAGCTTACCTGTCAAGATAAGTTTACCTTTTCCAGGTGATAAGGATACTTCAATTTGAAGGATATCACCACCGACAGTCGTATAAGCTAGTCCAGTGGCTACGCCAATTTGATCTTCCAGTTCCGCTTGACCATATTGAAAAATTGGCTTTCCGAGAAATTCCTCGATCGTTTTATCTGTTACGATTACCCGTTTTTTCTCCCCAGAAACAATCACTCTTGCCGTTTTACGACAGATAGTTGCCAATTGCCGTTCAAGACTACGTACACCAGCCTCACGGGTATAGTAACGGATTACTTTTGTAATCGCCTCATCACGAACTTGAAGCTGTGCTTTAGTTAATCCATGGTCTTTAATTTGCTTCTGCAATAAATGATCCTTAGCAATATGAAGCTTTTCCAGTTCTGTATATCCAGCAATCGTGATAATTTCCATCCGGTCACGGAGCGGTCCAGGGATAGTTGATAAATTATTAGCAGTTGCAATAAACATAACTTTTGAAAGATCATATGTTTCTTCAATATAATGATCACTAAAATTATTATTTTGTTCAGGATCTAATACTTCCAGCATAGCAGCCGAAGGATCGCCACGGAAATCACTAGACATTTTATCAATTTCGTCTAGTAAGAAAACAGGGTTAATAGTTCCTGCTTTTTTCATTCCCTGAATGATTCTACCTGGCATTGCCCCCACATATGTCCGGCGATGTCCACGTATTTCAGATTCATCACGGACGCCTCCTAAAGAAACACGGACAAAGTTGCGGTTCATCGAAGTCGCGATTGAACGTGCAAGACTTGTTTTACCTACTCCTGGAGGTCCAGATAAGCAGAGAATTGGACCCTTTAGAGAGTTGGTTAGCTTTTGGACAGCTAAATACTCTAAAACACGTTCTTTGACTTTCTCTAAACCATAATGATCTTTATGTAGGATACGTTCCGCTTTATGGATGTCAAGGTCATCATCTGTCGCTTTTGTCCAAGGTAAGGAAATCAACCATTCAATATAATTCCGGATTACGGCACTTTCGGCAGAACTAGTAGGTACCTTTTCATACCGGTCTAGTTCCTTTAAAGCCACTTCTTTTACATGGTCCGTCATTCCTGCGTCTTCTATTTTTTCAGTTAGCTCGGCAATTTCACCGGTTTTCCCTTCCTTATCTCCAAGCTCCTTCTGTATGGCTTTCATCTGTTCACGTAAATAGTATTCCTTTTGAGTTCTTTCCATTGATCTTTTAACACGCTGACCAATTTTCTTTTCAAGATTTAATACTTCTTTTTCATTTTGAATAATATCGATTACGTGATTCATTCTTTCTTTTACATCAACGGTTTCAAGAATTTCTTGCTTATCCTTCAGCTTTAATGGGAGATTAGAAGCAATAATATCCGCCATCCTGCCAGGTTCATCAATATCTGCGACAGAAGAATATGTTTCAGCAGATATTTTTTTTGACATTTTTATGTATTGTTCAAAATGTTCGAGCATCGTTCTCATTAATGCTTGATCTTCGATATCTTTAGATGGATCGTCCTCAAAGGTTTTCAGACTTGCAACATAATGATTGTCATCATCATGCATTAGAACGATTTCTGCTCGTTTCAAGCCTTCTACCAATACCCGAATGGTACCATTCGGAAGCTTGAGCATTTGTTTCACCCGAGTCAGTGTCCCCATATGATATAAATCTTCTTCTGCAGGTTCATCAATTGACACGTCTTTTTGGGTTGTTAAAAAAATTAAATGGTCATCTACCATTGCTTTTTCAAGGGCTTGCACCGATTTCTCCCGGCCTACATCTAAATGAAGGACCATTGTTGGATAGACTAGTAACCCTCGAAGAGGCAGGAGGGGGACGATGAGCTCTTCAGTTTTCGTCATAGTGTTACACCTCCAAATGCGAATTCTTTATCTTTACCCACTTTAATCATAATTCAGTTAAAGTGTTTGTACAATCTTAACGTATTAAATTCCATAAGAAAAGAGGAGACAAGCAAATAAAAACTTCGGTTTGACGTATTCCTGGCAAACCGAAGCGTATTAAATTAAACACTTTCCTTTTTCGATAAGTCAATAGTGGCTGAGATAATTTGATCTCTTGGATTTCCCTTCACAAAGGCCATTTCAAAAACCTCATGCAACTGAGTGACTGGGATAATGGTAATCCCTTCAATTTCAAGTAAAATTGATTGCATGTTTTCTTTAGGAATAATAACTGCCTTGGCCCCTGCCTTTTTGGCTGCCTTTACCTTTGGATACACACCACCGATTGGCTTCACATTTCCATGGATACTGATTTCTCCAGTCATGGCAATCGTATGATCAATTGGAATTTTATATATTGCCGAATAAATACCTGTTGCCATTGCAATTCCTGCTGATGGACCATCCACTGGTACACCGCCAGGAAAATTCACATGAATGTCATATTCATCTGCGGGTACTCCAATTGATCTTAGTACCGTAATCACATTTTCAATCGAGCCCTTTGCCATACTTTTTCGACGAATGGATTTACTGCGGTCACCGATACTTTCCTCTTCAACAATACCAGTAATATTGATTGATCCTTTGTCTCTTGCCGGAATGACCGTTACTTCTATTTCTAAAATCGAGCCTGAATTGGGCCCGTACACCGCCAACCCGTTAACCAGTCCTATGGTTGAAATAGGGTTGATCTTTTTCTCTATTCTCGGAGTTAGTTGACTTGATTGAATAATCCATTCAATCTCCTCATCTTTAATAAAATTTCTTTCCTCCGTAATGGCGAGTCCAGCAGCTATTTGAATCATGTTGACTGCTTCACGTCCATTACGGGCATATGTAGATAGAATATCTAATCCACCATCACTGATAGTCAAATTCACTTTCTCAGCTGCTCTTTTGGCTACAGCGGATATTTCTTCTTGTGTTAACTCTCTAAAGAAGACTTCCATACAGCGCGACCTAATCGCCGGTGGAATTTCGTTTGGAGTTCGAGTTGTAGCTCCAATTAACCGAAAATCTGCCGGAAGACCATTTTTAAAAATATCGTGAATATGGCTTGGAATTTGTGGATTTTCTTCATGATAATATGCGCTTTCAAGATAAACTTTACGATCTTCTAACACTTTTAAAAGCTTATTCATTTGAATCGGATGTAATTCACCAATTTCATCGATAAAAAGGACACCGCCATGTGCATTGGTTACCGCACCTTGTTTTGGTTGAGGAATTCCAGCTTGTCCCATCGCTCCTGCCCCTTGGTAGATTGGGTCGTGAACGGAACCTATTAATGGATCAGCAATCCCTCTTTCATCAAATCGCGCAGTGGTTGCGTCCAATTCGATAAAAACAGATTCCTTTTGGAATGGTGACTTTTTGTATTTCTTTGCCTCCTCAAGCACAAGCCTTGCTGCAGCTGTCTTACCAATCCCAGGTGGACCATATATAATGACATGCTGCGGATTCGGACCACAAAGTGCCGCTTTTAGGGATTTAATCCCATCCTCTTGTCCTACTATATCTACAAAACTGGAAGGGCGTACTTTTTCTGACAACGGTTCGGTTAAAGCAATTGATCTCATTTTTCGTAGCTGTTCCATTTCCTTTCGAGATTCTTTGTCGATAGAAACTTTTTGGCTTCGCTGATTTTTTAATAAGTTCCAAAAATAAATCCCGATTACAATCCCGAAAAAAAGCTGTATAAATAAGGCAATCCCCGTCCAATTCATCGTATTCCCTCCTGGATTTAATAGTAGCTTATGATAATAGCTAGTATCCCCGACCCAAAGAAGGAATAAACAAAAAATATTTTAATTAGGAAAGCGCAGTGCACATGGTTAATTTTAGCCATAAAAAATCCAACCGAAAAGAATCTCGGTTGGTTTTTTTTAATTTCACGCAGATGTTTTTCGTTTTTCATCAAAAATAGTGCCATCTTCAAGGATTAATTTTGGAATGCTATTTTCAATGACAGTTTCGTCAGTGATAATACATTTCGAGATATCATCACGTGAAGGCAAATCAAACATAACATCAAGCATGATTCCTTCAATGATTGAACGAAGTCCACGGGCACCTGTTTTGCGTTCAATTGCTTTTTTGGCAATTTCAGTTAATGCCTTCTCTTCAAACTCTAATTCAACATCGTCAAGTTCAAGCATTTTTTGATATTGCTTCACGAGTGCATTTTTCGGTTTAGTTAATATCTCAATTAAAGCACTTTCATCCAATTGCTCAAGGCTAGCAATTACTGGAAGACGCCCAATGAATTCAGGAATAAGTCCAAAACGTAGCAAGTCTTCTGGAAGAACTTTTCCTAATAGTTCTTTTTGACTAATATCAACCTGCTTATTATCGGTACCACCGAAGCCAATTACTTTTTGACCTAAACGGCGTTTGATGATCGGTTCAATTCCATCAAATGCTCCACCACAAATAAATAAGATATTGGTTGTGTCAATTTGAATGAATTCTTGATGTGGATGCTTTCTACCACCTTGTGGAGGAACGCTAGCCACTGTGCCTTCTAATATTTTTAGCAAGGCTTGTTGAACGCCTTCACCAGAAACATCCCGTGTTATTGAAGGATTCTCTGATTTACGAGCGATTTTATCAATTTCATCGATATAAATAATCCCTTTTTCTGCCTTTTCAACATCATAATCTGCTGATTGTATCAGCTTCAATAGAATGTTTTCCACATCTTCCCCTACATACCCAGCTTCAGTTAACGAAGTTGCATCAGCAATGGCAAACGGAACATTCAAAATACGAGCTAAAGTTTGAGCCAGTAATGTTTTTCCACTTCCAGTAGGTCCAATCATACAAATGTTACTCTTCGATAATTCAACGTCATCGATTTTGCTATTAGAATTTATCCGTTTATAATGGTTATAAACCGCTACGGAAAGAGACTTCTTCGCTTGATCCTGTCCAATTACATATTCGTCTAAAATGTCACGAATCTCTTTTGGTTTTGGAACATCTTTAAATTCCACTTCTTCTTCAGTGCCAAGTTCTTCTTCCACAATTTCTGTACATAATTCGATACATTCATCACATATATATACACCTGGTCCAGCAACTAATTTACGTACTTGATCCTGTGTCTTACCACAAAAAGAACACTTTAATTGCCCTTTTTCATCATTAAATTTAAACAA

Protein sequences of DBSCAN-SWA_3

>NC_021171|3583108:3644239|3634032_3634866_-|WP_015595154.1|DBSCAN-SWA
MFDIYMTRLHELTVLVYALSVLLYFIDFLHNNRKANQVAFWLLAFVWGLQTTFFLIYVVKTGRFPILSVFEGLYFYTWVLVTLSLGINRLLRMDFIVFFTNILGFVIMAIHTFAPVQYNSEVIAQRLVSELLLIHITMAILSYGAFSLSFVFSLLYLIQYDLLKRKKWGKRLLRIADLSRLEHLSYVLNVIGVPMLLLGLILGMQWAFIKVPNMTIFDAKVIGSFIVLCTYSINLYLRVVKGLQGKSLALWNVAAFLIVLLNFFLFGKLSSFHFWYA
>NC_021171|3583108:3644239|3621343_3621781_-|WP_015595144.1|DBSCAN-SWA
MEKFVGFIKKNEKGITLIELLAALALVSMVILLASSVQLFGQKQVNNQTNEIQNQSNVRLALNIVTKEIRKASNVSVTNNVLTINNTDIYKLENNILKKNNEPLISNIQSFTITKTEDKVTITITNTPSNNQPKTTLSATIYLRK
>NC_021171|3583108:3644239|3584273_3585302_-|WP_015595105.1|tRNA|DBSCAN-SWA
MKVDLFDFDLPEELIAQVPLVNRSDSRLMILNKQTGEIKHEIFKDITDHFQAGDCLVLNDTKVLPARLFGSKEETGANVEVLLLKQVEGDRWETLVKPAKRIKEGTKITFGDGRLTAICVGTSDHGGRTLDFGYDGIFYEVLDTLGEMPLPPYIKEQLEDRDRYQTVFARERGSAAAPTAGLHFTESLLNELRDKGVDIAFITLHVGLGTFRPVSVNDINEHEMHAEFYQMTEETAQLLNRVRDQGGRIISVGTTSTRTLETIASAHDGKFAQASGWTNIFIYPGYQFKAIDGMITNFHLPKSTLIMLISALAGRENVLRAYEKAVAEKYRFFSFGDAMLIV
>NC_021171|3583108:3644239|3632308_3633085_-|WP_015595152.1|DBSCAN-SWA
MTASSLPLYHKKVLVPRGKGQAKPFSDLVKKNGGIPIEIPLIAFRPVQLNDKLKEMITKLHTYDWIIFTSNVTVDTFLSMVNSQTLPKVAVIGARTKQVLEERGIPVAFTPSEYVAEGFVSEFLPLIQPGMKVLIPKGNLARDYIALALTEHGAIVTESVIYETYAPEESKKELAEMLSNEELDILTFTSPSTVDHFIEIVQEYNLSDKLKSCLVACIGPVSTKRAKALGLTVHVSPTEYTVKDMIKAIIENLNQVTR
>NC_021171|3583108:3644239|3586432_3587041_-|WP_015595107.1|DBSCAN-SWA
MFEYIKGTIDFVGPEYIVIDNQGIGYQVITPNPFIFSKQLGTEVRIYTYHYVREDIMALYGFQARQEKTLFTKLLNVSGIGPKGALAILASGNPEQVIYAIESEDEAFLIKFPGVGKKTARQMILDLKGKLQSVVPEIFPDLFTEDASSFDRHTLADWEEASLALKALGYSEKEIRKISPELQKEKLTTDQYIKKALQKLLR
>NC_021171|3583108:3644239|3612578_3613007_-|WP_015595137.1|DBSCAN-SWA
MLQKLKKRLKNHKGFTLIELLAVIVILGIIAAIAIPAIGNIIDKSRNDAVKSSAIQAIDAGRLFIASEGIPTDKTITAEELKTYLDNKNSNITITELYVDTTATGGTEISIKATGGDLTFDYATVADINSASKTETTIGNGQ
>NC_021171|3583108:3644239|3593890_3594742_-|WP_015595115.1|DBSCAN-SWA
MKVGYLGPKATFTDIAVRKMFPEYTGVPYLTIPECMDAVVLGEVDLAVVPLENALEGSVNITLDYLVHEVDLPILGEINVPIRQHFMVHPDHKDTWKETNRILSHTHAIAQCHKFLHSEFKGVFCENTTSTAAAAQYIQQHPEIKAAAIANDLAAEEYGLTIVKPDIHDISFNHTRFIILAKKTLALSEDHPHFHGYKTTIMVTLPADHPGVLHQVLSAFAWRKLNLSKIESRPMKTGLGNYFFIIDIEMKVDDVLIPGAMQELEAVGCNVTLLGSYPSYNLK
>NC_021171|3583108:3644239|3617066_3618386_-|WP_041580644.1|DBSCAN-SWA
MRNGKSIKLFIVLFLCTAFIYSFSHFGALAYESMTSTSDEFATGTKIGPIDVSGKTKSDALKLLSAPLQKWRSETKISLQYKEKTIPVDVGKFQIDLENSVATAKDGQQNEVIVTFKSSDLRELLKNASKELEDPKLIIDPILTELISYSTNLSAREYQLSVEKFLPKDFNKNEVLSEATITCDYTPLELGILVERLSPIKIEGYSQVSLLKLIEAQKLATFSPEAASMLATTIYEAILSSNFTIVERQTGVVLPEYASLGMEAKVDLDTHLDLVFVNPNDASYEIQLQRQDNTLTATLNGSKFLFDYKINIAEKQEFKPKTIIQYSPLLPANGTKVQQEGANGFLIKVYREIYDENGAWIRKEAISEDFYPPVPRIELHALTSSKTSESSDGQTDTSQATVDSGQNTTQYTNNKDGTASTQQSTLESDLYGKENETMK
>NC_021171|3583108:3644239|3590227_3591211_-|WP_144061606.1|DBSCAN-SWA
MSMKHKNGGDDLITNRLLNILKKSVPFKVNEIKQIRKHVYFVKTDHKPYILKGYSSLQRLYLQEAFTESLKAEGFHHSYSYYRILETPIYFNQKYFGWIEYIEPHRDRFSYQSSSDRKEGIRLLNRFHRTTKRLAKSYEMMLPRINLYEKWYERSSRFQKHIPLLRHYLKDQMINELMEWSKISLEGLKNENLNFGNDDLQPVILHGDVAHHNYLKSKSGNLYLIDFDLISIGNEGSDLLQYANRIFPFINWSMHELSKYEHINKYLNNRAFLLALMYPTDIFREWTRIIKDKTYQSPEKILPVMELTVDQFHLRRQLIKDLKNVVK
>NC_021171|3583108:3644239|3622446_3623751_-|WP_015595146.1|DBSCAN-SWA
MFQTYDEALSWIHGRLRLGIKPGLKRMEWMMERLNHPEQKIKTIHIGGTNGKGSTLTFLRCILEEAGYEVGTFTSPFFEHFNERISVNGKPITDAEMLELANVILPLADELDHSELGGPTEFEVITAMALYYFAKINPVDVALFEVGLGGRFDSTNIIHPLLSIITSIGLDHTNILGDTYEKIAAEKAGIIKNGTAILTAVKQDEAMEVIAAKAMESKAPLYQLGSEFSISGNHSLMRGEEFNFSSIFQELPQIQISMLGKHQTENAALAIMAAQLLKQFYALLIDEPHILQGLKRAYWPGRLELILEEPTIIMDGAHNEEGIEALVHELKARYNDKQIQILFTALSDKKLDKMIQQLDAVADSITFTEFAYPRASQAQFLYELSCSQNKHKAKDWKQYLRTTIPTLKENEILVITGSLYFLSEVKPFLVNLIK
>NC_021171|3583108:3644239|3634880_3636230_-|WP_015595155.1|tRNA|DBSCAN-SWA
MHIIVVGLNYKSAPVEIREKLTFNEANIGNAMQTLRSKKSILENIIISTCNRTEIYAVVDQLHTGRYYIKEFLSEWFGLEQDEFSPYLFIYELDGAVEHLFKVACGLNSMILGETQILGQVRSSFLLAQQENTTGTVFNQLFKQAITIAKRGHSETDIGANAVSVSYAAVELAKKIFGTLMSKHVLVFGAGKMGELAIQNLHANGASKVTVINRTFEKAQGLASRFDGEAKTLEELHTSLIEADILISSTGATEFVITKEMMVNITKLRKGKPLFMVDIAVPRDIDPQIADLESVFLYDIDDLEGIVEANLQERKKAAEKIMLMIEKEIVDFKQWLNLLGVVPVISALREKALVIQTETMTSMERKLSHLSDRDIKVINKHTKSIINQMLKDPILQAKEIAGEQNASQALELFIKIFNIEEQVEKQQLKNKAAESRQEMIHAPQASFQA
>NC_021171|3583108:3644239|3605370_3606393_-|WP_015595129.1|DBSCAN-SWA
MFGFGTKDLGIDLGTANTLVYVKGRGIVLREPSVVAFQTDSKQIVAVGNDAKNMIGRTPGNVVALRPMKDGVIADYETTATMMKYYIRQSTKTKGLFAGKPYVMVCVPSGITAVEERAVIDATRQAGARDAYTIEEPFAAAIGANLPVWEPTGSMVVDIGGGTTEVAIISLGGIVTSQSIRIAGDEMDDAIILFIRKHYNLMIGERTAENIKMEIGSAGDPEGIENMEIRGRDLLTGLPKTIEITADEISKALHDTVYAIVDAVKVTLEKTPPELAADIMDRGIVLTGGGALLRNLDKVISEETKMPVLIAENPLDCVAIGTGKALDHIHLFKNKARDSR
>NC_021171|3583108:3644239|3611803_3612553_-|WP_041580643.1|DBSCAN-SWA
MLYLLLFIYGILFGSFYNVVGLRVPVGQSIVSPRSACPTCGHQLRAFELIPVLSYLFQGGKCRVCKTGISPIYPIIELFTGVLFATAPLVVGWGSELLIALTLISLFIIILVSDVAYMLIPDKVLLVFAGIFLMERLFFPLLPWWDSLLGAAIGFVVLLAIALVSKGGMGGGDIKLFALIGFVVGVKILLLAFFLSTLFGAIIGGAGMAVRIFEKGKPIPFGPFIGAGTLVAYYYGDKIIQAYFNLFFS
>NC_021171|3583108:3644239|3621765_3622212_-|WP_041580648.1|DBSCAN-SWA
MKKITCYFSSEKGITLIEILASMVILSIIIVSLIAMFVQSSRTNAMSKNIMDATYIAETNMEEIYNIVVASTSYDIATAAIVSKGYTQASKTTTNAFYQKNVTGHYVSIELVPTINSSLVKVRVKVFKDNTKTKKEAQMEILLSWKNL
>NC_021171|3583108:3644239|3607290_3607863_-|WP_015595131.1|DBSCAN-SWA
MQHLILASSSPRRKELLENLQLIFDISSSETDESFLPGTAPEEIVMDLAARKATDVAEKHRDSIVIGADTIVFANNQVLGKPKDKIEAVKMLKMLSGNTHSVYTGVAIVTADTTVRFYEKTDVTFWDLNDSEIQAYINSGEPFDKAGAYGIQGFGSMLVKRISGDYFTVVGLPVSKTIRELQKAGFVLPY
>NC_021171|3583108:3644239|3614326_3615367_-|WP_015595139.1|DBSCAN-SWA
MRERIDLLLRAAFELKASDIHLTVSVQPIFRIHGELKRYGKEVLKPEDTEAMARAITPDGKWGVFEEMGELDFSYSIPNVSRYRVNIFKQRGCVALAIRTVPTRIPTIDELNLPDTLRRIVEKKQGLILVTGPTGSGKSTTLAAMINYMNQTMHEHIITLEDPIEYLHKHGMSIIDQREIGFDTKNFGNALRAALRQDPDAILVGEMRDFETIQIAITAAETGHLVFGTLHTSSAPASVERMIDVFEPAQQPQVRTQLASVLLSIISQRLFKTADGKGRRAALEILINNAAIANLIRNDKIHQIESTMQTSRSQGMQTLEMSIKELLETGVIAQEVADPYLKGPVN
>NC_021171|3583108:3644239|3636584_3637067_+|WP_015595156.1|DBSCAN-SWA
MKNQRYFSGIIFIGFGGYFLLQHTNIAFLQQFTGWPTLLMIVGLAFLWQGYVGRESELIFPGVVLFGFGLHFYVTTNLHIWTDQIGIFILILALAYILKYQKTGVGLVQGILFAILSALLLFQDSVMGWFGTVESKVTYIWDFWPIFLILFGIYFLMKKK
>NC_021171|3583108:3644239|3598232_3598541_-|WP_015595121.1|DBSCAN-SWA
MYAIIETGGKQIKVEAGQAVYIEKLNAEAGETVTFDKVLFVGGETVKVGSPVVEGATVTAKVEKQGRQKKIIVFKYKSKKNYRKKQGHRQPYTKVVIEAINA
>NC_021171|3583108:3644239|3638068_3638653_-|WP_015595158.1|DBSCAN-SWA
MKVNNAEIIISAVKPEQYPGGIMPEFALAGRSNVGKSSFINKMLNRKNLARTSSKPGKTQTLNFYLINEQFHFVDVPGYGYAKVSKSEREAWGKMLEIYITSREQLRAVLLIVDLRHPPSKDDVLMYDFLKHYQIPVIVIATKADKIPKSKWQKHVRITKETLNMLESDLLVMFSSETGYGKEKAWAVLESFMK
>NC_021171|3583108:3644239|3609379_3610156_-|WP_015595133.1|DBSCAN-SWA
MTLRFSKKEIIILMVTIFLTISMILSGYYFYLSPKKEEIETKSVELKSAQDLLTALQSKPTESSPVTVESVAALQRKVPVKPQSEKLIFDLEKAEVVSGSEIKNMAFSEADVSVPQQNTTQQQPAATDANQKSDTTKKNENTDSQPQTTEQINASTTKATAQTQKAAVPTGIKKLTVTLQVESPSYDELKIFINTLENSTRIIVIESVGFTGSGEKTNLDTEKKKLSFTVTLSAFYMPTLTDLQSQLPELVVPKSDPL
>NC_021171|3583108:3644239|3596645_3597188_-|WP_015595118.1|DBSCAN-SWA
MRKDWSTVEVLAHARHDWLNKIQLIKGNLALNKIERVKQIIDEIVIETKQEAKLSNLKIPRFASLLLTANWEAHSFQLEYEVVHESGVILSLDDHLLSEWTSSFFECLHTAVDEIHENNLAVSVETQKNGIRFFFDFSGIIKDKNKLQQFLDANHNNQLTIKVLEFSQQELALDTFMPFR
>NC_021171|3583108:3644239|3608064_3609207_-|WP_015595132.1|DBSCAN-SWA
MDKREPGKTITIKINGKQQSFEETRQKSDRKQDQFINDRKDIVTTEKVPMEQRFEKTKPVKMPQKDREDFTTISEAAVAHDPSEESFDWILPDSTSDIRKIKEYKMTAEANHSQKKSSKKWPIGKRKIDKRMFTTIFTAVFLAVLLGTSFGFTMLKLVFIEHPAQTSTVQKPTTTPEPEKKQAEQQSGKLSLVPPTITTWVVQEGVYSNKDSATQIVNSLKEKGASAATFESNGQSFLLLSVADTKDHAKEFGEILKESGVTEFIAKEMSFSGHEISGLQVQEKTYIEGIPLLFETMTTAASIASATDSFPKALLDSINQQSKKLAPKKDTLSNEKIKELKVQVDAATQNINSMEKSVGKQKLTSLQQQLLSILTAYQAL
>NC_021171|3583108:3644239|3602274_3603078_-|WP_015595125.1|DBSCAN-SWA
MGEAIVITSGKGGVGKTTTSANLGTALALQGKRVCLVDTDIGLRNLDVVMGLENRIIYDLVDVIQGRCKIHQALVKDKRFEDLLYLLPAAQTLDKTAVTPEQMKKLITELKQDYDYIVIDCPAGIEHGYQNAVAGADRAIVVTTPEVSAVRDADRIIGLLEKEENMEAPKLVINRIRNHLMKNGDMLDVDEVTAHLSIDLIGIVADDDEVIKASNHGEPIALNPNSKASIAYRNIARRILGESIPLQSLEADEKGVFTKIKRFFGAK
>NC_021171|3583108:3644239|3597888_3598221_-|WP_015595120.1|protease|DBSCAN-SWA
MIRIKINRTESGKIHMFSMSGHANFADHGEDIVCAGASAVSFGTLNAIEVLTGFVPEVDLGKDGFLRCVFPDNLAEDIQEKVQLLLEAMVVSLKTIEREYGKHIKITFKK
>NC_021171|3583108:3644239|3615379_3617041_-|WP_015595140.1|DBSCAN-SWA
MKYTRKRLGDLLVEAGLITEEQLQLTLSEKTPGQKLGDALLQKGYLTEQQLIEVLEVQLGIPHLSLYNYPFETNLFSLVSKEAAMRNLLIPLRRDGDKLLVAMADPMDFFSIDDLRLSTGFQIEAVISTKDDIVRAINKFYDMDNEFDDLLDGMKKGDNPQEETITDEDSPIVRLVNQILANAVAHKASDIHFDPQETKLVVRYRIDGLLRVERVLPKNMQSFLTARIKIMANLDITEHRIPQDGRIKINLNFYPIDLRVSTLPTVFGEKIVLRILDLSNALIDIDKIGFNKVNLTRFLRMIERPNGIVLITGPTGSGKSSTLYAALNNLNNETVNIITIEDPVEFQLEGISQIQVNQNVGMTFATGLRSILRQDPNIIMVGEIRDKETAEVGIRASLTGHLVLSTLHTNDALSSVTRLIDMGMEPFLVATSLSGIVAQRLIRKVCRDCGEPHDATNREIEIFANRGLKIDKIMRGKGCVSCNMTGYRGRIAIHEVIVVNEEMRHVIMNSGSVANLRQIAVKNKTIFLIDDGLLKVKQGLTTTEEVLRVAISE
>NC_021171|3583108:3644239|3637505_3637763_+|WP_015595157.1|transposase|DBSCAN-SWA
MGRVTMLINIRSVFRISGVLKTFRFVRTTTIFVKTAFRIEKIELSFADLMEMHGLRYCRLPGMKNVSEQPLLPAACQKIKKLQHI
>NC_021171|3583108:3644239|3631308_3632289_-|WP_015595151.1|DBSCAN-SWA
MKKLQFTRHRRLRSTANMRALVRENQLNVNDFIYPLFVIEGNNIRNEISTMPGVFQLSLDNLAAEMDEVVALGIKSVLLFGIPSEKDECGTGAFHDHGIVQEGTRFIKKHYPDVLVVADTCLCEYTSHGHCGVIENGTVLNDPSLELLVQTAVSQAKAGADIIAPSNMMDGFVVAIRAGLDEAGFEDVPIMSYAVKYSSAFYGPFREAAESTPQFGDRKAYQMDPANRLEAFREAESDVIEGADFLIVKPGMPYLDIVRDVKNNFNLPVVIYNVSGEYSMVKAAAQNGWIDEKNVVMEMLIGMKRAGADLIITYFAKDAAKYLKEQ
>NC_021171|3583108:3644239|3587197_3587725_+|WP_015595108.1|DBSCAN-SWA
MKRLLAFLTIFTLMFAVAGCSSTKDDTSKTTTEKKATEKTSELTDQVKSKMYNAVRIAEGKVNEVFAKEMAADETTPVLTSTFADEAAAEAFLSKYYSADIAKEIYTYYVTDQKTTDGQTIVKADPFFAKPILDTTKDDVTVEGDANKATVKTKDNVTYTVELKDNTYVVTAIQK
>NC_021171|3583108:3644239|3585346_3586348_-|WP_015595106.1|DBSCAN-SWA
MEERLISGEADYQDESYEQSLRPQTLNQYIGQDKIKANLDIFIKAAKLRQETLDHVLLYGPPGLGKTTLATIIANEMGVNIRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLQRSIEEILYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGSISAPLRDRFGVLGRLEFYTVEDLANIVTRTAEILETKIDPFAASEIAKRSRGTPRIANRLLRRVRDFAQVDGNGEVDFHLANESLERLQVDRLGLDHIDHKLLKGIIERFRGGPVGLDTIAASIGEESQTIEDVYEPYLLQIGFLQRTPRGRVVTDLVYRHFNMETPEM
>NC_021171|3583108:3644239|3593023_3593560_+|WP_015595114.1|DBSCAN-SWA
MKEQKKILGEERRAFLLQMLKESSVPITGSEFASKTKVSRQVIVGDITILKAKREPIIATSQGYIYLKQPTSSSIYERTIACNHPPDRTEEELIILVDHGVTVRDVKIEHPVYGDLTASIMVANRKDVKHFMDKIRMTKATYLSELTNGIHLHTISAPSEKILDDAVQALEMANFLIE
>NC_021171|3583108:3644239|3629982_3631272_-|WP_015595150.1|DBSCAN-SWA
MRSYEKSIAAFQEAKTLMPGGVNSPVRAFKSVNMDPIFMAKGKGSKIYDIDGNEYIDYVLSWGPLILGHTNDRVVEAIKKVAELGTSFGAPSLIESELAKLVRERVPSIEIIRMVSSGTEATMSALRLARGYTGRSKILKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGVAKNTITVPYNDLEGVKYAFEQFGDDIACIIVEPVAGNMGVVPPQPGFLEGLREITSQAGALLIFDEVMTGFRVGYNCAQGFFGITPDLTCLGKVIGGGLPVGAFGGKAEIMEQIAPSGPIYQAGTLSGNPLAMTAGLETLSQLSPENYVEFVRKADMLESGFKALAEKYDVPLTCNRAGSMIGFFFTNENVINYDTAKTSDLEFFANYFREMANQGVFLPPSQFEGIFLSTAHSDEDIQKTIQAAEVAFSKLKG
>NC_021171|3583108:3644239|3604372_3605257_-|WP_015595128.1|DBSCAN-SWA
MPQFFLNKRLIILLVSMIILVALIGFSIRDRKQLTWPEQFMKDTTGFVQSLVSKPANYVAGFFENLNDLQNTYNENKELKKRVDKIASLEAEVQLLEKENKKLNDVLGKKETLRDYDPTQATVIARNPDRWNEQVIINKGSVNGIEKKMAVVTASGLIGKVNSVNKFTSTVQLLSANDSKNRISAVILGGEQEVHGLIMGYDEKKKLLLLKQIPADAKVAKKQNVVTSGLGGIFPEGLPIGKVVKVVPDEYGLTQTAYIKPGADFYDIENVMVIQRKMAQPQSSDMVDDKGEEL
>NC_021171|3583108:3644239|3603079_3603760_-|WP_015595126.1|DBSCAN-SWA
MKKMQNVTIKGTKDGIILHLDDSCSYDELKKELDQKLSANSRINEDQPLTSVKVQMGNRLLTEKQNEEIKDLIRQKKNLVVDEIVSNVITIEEAKRKKAESEIKSVNRIIRSGQVLEVPGDLLLVGDVNPGGTIKAGGNIFVMGTLKGIAHAGCFGDDQAVITASIMKPSQLRISDCINRSPDQFAETEERLLECAFIDDNRQIVVDRIQVLMHLRPNLTRLEGGL
>NC_021171|3583108:3644239|3598927_3600403_-|WP_015595122.1|DBSCAN-SWA
MKKLIVNHALTEKRFALVSETSVEKIVIEQPQQQSSVGSIYLGTVTKVLPGMNAVFVDIGEEKNGYLQREKLSRYVLSKDSGEVKRNKSVSAFSFQGEKLLVQVEKDETGTKGPRLTGIIELYGESVILLPKGRSVSVSRKIPDKLERQAWEKMATRIKTEEEGLIIRTSAQGQSEQKVSTEIEELRKQFADLIKASEQRKKPGILVKRDLFLAQIEKECRILTSGEVLVDDLGLKQRLEKFVRENVTVTYYQGKENIFHVHHIEHEIEQALHRNVELENGAYLVIDQTEALTVIDVNTGKFSGKNHLAETVVKTNLVAAVEVAKQLRLRDIGGIILIDFIDMKNEQDRMQVQKTLEIELSKDEKQSKVISFTALGILQLTRKKTKQALSEALTVACLVCEGSGRVLSPETVAFRLERELWEHRFTDNEAVWIETTEEVRSVFSGENNVHLFRFQELLGLTIFLTLQSSAKPFYLIRQFGKVQELKARIQL
>NC_021171|3583108:3644239|3587768_3588287_-|WP_015595109.1|DBSCAN-SWA
MNARMSVLSAVAASFLLVFFHESIGCAEGKAVSRHEAEIQRVKVILQRVYLDGDLGEEIVMESVLTKQEIQEKYKQWQLIEQQGNILIFRNQVDDISPLLKANGYFGITKEGTLTIFNGRPKHSKVIHSFFQIDVGKLESRKKQQLKRGIPVKSKNRYQQVLETFKPYSKFE
>NC_021171|3583108:3644239|3641137_3642805_-|WP_015595160.1|protease|DBSCAN-SWA
MNWTGIALFIQLFFGIVIGIYFWNLLKNQRSQKVSIDKESRKEMEQLRKMRSIALTEPLSEKVRPSSFVDIVGQEDGIKSLKAALCGPNPQHVIIYGPPGIGKTAAARLVLEEAKKYKKSPFQKESVFIELDATTARFDERGIADPLIGSVHDPIYQGAGAMGQAGIPQPKQGAVTNAHGGVLFIDEIGELHPIQMNKLLKVLEDRKVYLESAYYHEENPQIPSHIHDIFKNGLPADFRLIGATTRTPNEIPPAIRSRCMEVFFRELTQEEISAVAKRAAEKVNLTISDGGLDILSTYARNGREAVNMIQIAAGLAITEERNFIKDEEIEWIIQSSQLTPRIEKKINPISTIGLVNGLAVYGPNSGSILEIEVTVIPARDKGSINITGIVEEESIGDRSKSIRRKSMAKGSIENVITVLRSIGVPADEYDIHVNFPGGVPVDGPSAGIAMATGIYSAIYKIPIDHTIAMTGEISIHGNVKPIGGVYPKVKAAKKAGAKAVIIPKENMQSILLEIEGITIIPVTQLHEVFEMAFVKGNPRDQIISATIDLSKKESV
>NC_021171|3583108:3644239|3627144_3627339_+|WP_083935128.1|DBSCAN-SWA
MVKRRYNPHALPPWLRYIRGSCCQFIIPLCVFQVIRTIILPTTFDALLLTILILLALAFQFDMI
>NC_021171|3583108:3644239|3618445_3619738_-|WP_015595142.1|DBSCAN-SWA
MESLLFAGVSLLILFPILYFLPIGFTVKGKVLLAVASFLIGLFGLVASIVFSLWQTGWILLMFVGTSSYFINKKGGKWLYLPEVNQDPFFKEEQQPDSPAEEVVINDNYSYIASSDKKVELDKRDKKFAKKQKTLKSKDSEVIQHTAENQIAAAVIQKPVPTTLLEKLVFQNDHELSLIRKPDEDNLDDTEIEEIVLDEEDRIKLKKPVGIEDLTSAKGNLALVENVELDVLDIDFVEPELQEPGFADTSDSKLEDYRIDSIEMLEPKSSISETTDDLVFDLETLLEEGDEPLEQQEPSSIIIEQSHDYMSEIEKMIESDELGSDSIQPLEEIAIQTPQTDDSLEVISNPKAPKEEISEDAPAPSNDFEVEIEELSLEDLIKEINGNVVQEQKAVKEPEYELEEMVFANQRIQRTTTNQTPKEQVLIEKR
>NC_021171|3583108:3644239|3619993_3621334_-|WP_041580646.1|DBSCAN-SWA
MKNWYSKIKSLNNENGVALVTVLLVFVVISIMGFSLMGLAASNIKMTSGERNNQSSYYIAESGITYKMNDIRTKLSTIYGQSLSYTDFFSSVDNLMELGQEKTVENLFEESFGGNPVVKIKIEKLQDGTVVSYSNNYKITSTGTINNRSRTVVKIIHLTWKPKSGVTIPADTVLFVQENLTLKNVPVDGSIGTNGTATDITLNGSKAIVTGNIYTNVGTQLNIPEFPLFTIPTNAANFTDTTLKMDQDMVLNNLTVNANQTLTIDVGYINKNLVVNNLTLLSGAKIQIVGSAKLSIYAKNISMTSGSILNTGGDFEKVYIFLEGTASNIYGLINASMYAKNSNLVVNNFVSGVQGHIVTSGTSISIVGSGTANYPKMIFAPNATVNINASFAGSIIAKSLSSQGNDDSFIFKFVQINYDNSPLFVDNGTGLSPVKDTITGEPVREQ
>NC_021171|3583108:3644239|3610152_3610791_-|WP_015595134.1|DBSCAN-SWA
MLVDINLLPKKEPKNVAFLTIIFSAVFILLVAGIVIFWQGYTQGNQLKSLKNQIFAVNKLAETEKAKQTNTAQASASLTQLEAAVKWANEEPLKSVPVLKDIDSLLLQRGLIQTIAYTEAGTVTLTAQFDTSQDAAYFYKTLLDSKWISEAKLSSLTVSELKQTKTIDSEQTTSDQSQYIPRYIGQYQITLNRDYINQEEKAEKDQQGGDAP
>NC_021171|3583108:3644239|3606552_3607224_-|WP_187292196.1|DBSCAN-SWA
MIRDFPQDERPRERFMNSGPESLSNHELIAIMLRTGTKSESVLQLSNRLLNHFEGLRLLKEASLEEITAIKGIGTAKAIQVLAAVEIGRRIANLVHEDRYVIRSPEDGAKLVMNDMRFLSQEHFVCLYLNTKNQVLHKQTIFIGSLNASIVHPREVYKEAFRRSAASIICLHNHPSGDPAPSREDIEVTKRLAECGKIIGIDLLDHLIIGENKYVSLKEKGYL
>NC_021171|3583108:3644239|3627480_3628533_-|WP_015595148.1|coat|DBSCAN-SWA
MNANNNLNGVASILAHYAVEPYYVEDLGKIQKVYSNKGAFALKMIPPQLGTEFIRHIQTLYQKGYNRIVPIYPAMDGRYAVLHQNMLYYLMPWLENEAKEDPVERNKKLFRELARLHTLSSREVPIKKEDRKEHYENTLLLLEKDEEFITGFLESSEKKIYMSPFELQFCLYYHEVKQAIQYSKRRLEAWYEKTKDLEKVRTVLIHGKFSPEHFLFDDKGYGYFMNFENIKEGSPYQDILPYLHQTLKGLPKRSEECIEWLLIYYKYFPLKEEEKHLMLSYFSHPSAIIKVLKKYHKQQPGKKERKFSQQLQRKYWLLKNTEYVVMRLEEIEQQKAQALAQAQQQEGAQD
>NC_021171|3583108:3644239|3623964_3626610_-|WP_015595147.1|tRNA|DBSCAN-SWA
MDTKEISMPTKYDPQAIEQGRYDWWLKGKFFEAKDDETKQPYTIVIPPPNVTGKLHLGHAWDTTLQDILTRMKRMQGYDVLWLPGMDHAGIATQAKVEEKLRGEGKTRYDLGRDKFVEETWKWKEEYAGHIRQQWAKVGLGLDYSRERFTLDEGLSDAVKEVFVSLYKKDLIYRGEYIINWDPSTKTALSDIEVIYKDVQGAFYHMKYPFADGSGYIEVATTRPETMLGDTAVAVHPEDERYKHMIGKTVILPIVGREIPIVGDDYVDMDFGSGAVKITPAHDPNDFELGNRHNLERILVMNEDGSMNARAGQYQGMDRFECRKQIVKDLQEQGVLFKIEDHLHSVGHSERSGAVVEPYLSTQWFVKMQPLADAAVALQSEEDKVNFVPDRFEKTYLHWMENIRDWCISRQLWWGHRIPAWYHKETGEIYVENEPPADIENWVQDNDVLDTWFSSALWPFSTLGWPDKDSADFKRYYPTACLVTGYDIIFFWVSRMIFQGIEFTGGRPFNDVLIHGLVRDAQGRKMSKSLGNGVDPMEVIDQYGADSLRYFLSTGSSPGQDLRFSVEKVEATWNFANKIWNASRFALMNMDGMTFEEIDLSGEKSVADKWILTRLNETIENVTRLSDRYEFGEAGRALYNFIWDDFCDWYIEMAKLPLYGDDEAAKKTTRSILAYVLDQTMRLLHPFMPFITEEIWQNLPHSGESITTASWPVVDAALVDDQAAGEMKLLVEIIRSVRNSRAEVNTPLSKKIKMILKAKDAGVLAVLEKNRGYIERFCNPEELVIAVEVEAPDKAMTAVVTGAEIILPLAGLINLDEERARLEKEVERLNKEVERVQKKLGNEGFVKKAPAKVIEEERAKEQDYIEKRAAVQVRLNELKSL
>NC_021171|3583108:3644239|3597585_3597876_-|WP_015595119.1|DBSCAN-SWA
MLRLDLQFFASKKGVGSTRNGRDSQSKRLGAKRADGQFVSGGSILYRQRGTKIYPGTNVGRGGDDTLYAKVDGVVKFERVGRDKKQVSVYPVAQEA
>NC_021171|3583108:3644239|3610793_3611786_-|WP_015595135.1|DBSCAN-SWA
MALPLISVSNRPIDIIINDHSIRYLEMKPSNPPLPIKWGERYLPPGVVKEGKIIDPDTLKIILDECIDIWKIRRRKVRFLAPDSYVTIRRITIPSDVTYDEIKGYLYLEIGSSIHLPFEDPVFDYIVLPVQEEKKEILLFAAHQRYVMQFTDLFSSLKLIPEVADLSSLALYRLYHQLRKPKQEEKLFVLQFDLDLVVMSIFENEIPFFIRHMYIPFEEKDWDIQIGRSGFQQLTFIGEKNELYQQFDESFKEVNKLIEFYQYSLHQGKNEISKILLTGDHPLLDDIMKELQTRFEIKVEILDAEELQTDKNKPLPRSHYLAFGLALKEV
>NC_021171|3583108:3644239|3603857_3604376_-|WP_015595127.1|DBSCAN-SWA
MRRVLLPVLFTGCFIFESIFIELMPAKFFSGQHILVPHLLIMAILFLTIYGNRNLGILYGFIFGLLFDVVYTEVVGIYLFMFPVIAYLISKIMKVLQTNLIIVSIVTLLGVGLLEIGVYEMNFLIHRTTMGFPSFFGNRLVPTLVLNLIFIILVAYPLKRQFEKLADQLRNE
>NC_021171|3583108:3644239|3589450_3590191_-|WP_015595111.1|DBSCAN-SWA
MEQVIEKLVQWLQQKVKESGTNGAIVGVSGGIDSAVVTHLIKRAFPNDSVGLIMPTKSNPKDREDALKVIESCGIKHFTVELTETHNTLFSEIESQLKETGDWNEEKSKLGDANTRARLRMTTLYAVANNFGYLVVGTDNAAEWHTGYFTKYGDGGVDLVPLVHFTKGEVRELAKALGVPDEVINKAPSAGLWEGQTDENEMGTTYNMIDRYLKGEEIPEKDQKIIDRLHAVSEHKRNLAAAPPKF
>NC_021171|3583108:3644239|3588615_3589362_-|WP_015595110.1|DBSCAN-SWA
MNKKSLLLPIAGFISIALAGCSNNGESAGQARHVQKTQPLGYYSNEKHHNGNARILDDNDGPVTEIMDHSFGSEGKYERNQESRILQVRDENGNPENPTKPLATKDRNFFQKDNRYSTSDVNYHGHLDGKQRKLRSTNDTVYEVRLADKIDGVAATIPNVQDVHCVVYKNNVLVAVDVADVSKEAQTRQKVLQAVQPYLKGRSVNIVTDEATFSRIRDIENNIRGGRLRDGIDMNIRDIFDSVNNQSR
>NC_021171|3583108:3644239|3638639_3640973_-|WP_015595159.1|DBSCAN-SWA
MTKTEELIVPLLPLRGLLVYPTMVLHLDVGREKSVQALEKAMVDDHLIFLTTQKDVSIDEPAEEDLYHMGTLTRVKQMLKLPNGTIRVLVEGLKRAEIVLMHDDDNHYVASLKTFEDDPSKDIEDQALMRTMLEHFEQYIKMSKKISAETYSSVADIDEPGRMADIIASNLPLKLKDKQEILETVDVKERMNHVIDIIQNEKEVLNLEKKIGQRVKRSMERTQKEYYLREQMKAIQKELGDKEGKTGEIAELTEKIEDAGMTDHVKEVALKELDRYEKVPTSSAESAVIRNYIEWLISLPWTKATDDDLDIHKAERILHKDHYGLEKVKERVLEYLAVQKLTNSLKGPILCLSGPPGVGKTSLARSIATSMNRNFVRVSLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAGTINPVFLLDEIDKMSSDFRGDPSAAMLEVLDPEQNNNFSDHYIEETYDLSKVMFIATANNLSTIPGPLRDRMEIITIAGYTELEKLHIAKDHLLQKQIKDHGLTKAQLQVRDEAITKVIRYYTREAGVRSLERQLATICRKTARVIVSGEKKRVIVTDKTIEEFLGKPIFQYGQAELEDQIGVATGLAYTTVGGDILQIEVSLSPGKGKLILTGKLGDVMKESAQAAFSYVRSKATELGIDEDFHEKHDIHIHVPEGAVPKDGPSAGITIATALVSALTGKPIRREVGMTGEITLRGRVLPIGGLKEKTLSAHRAGLTKIILPKDNEKDIEDIPESVREQLEFVLVSSIDQVLKHALIGEGNESK
>NC_021171|3583108:3644239|3633081_3634017_-|WP_015595153.1|DBSCAN-SWA
MRKIIVGSRRSKLALTQTNWVIDQLKKLGGSFEFEVKEIVTKGDRILDVTLSKVGGKGLFVKEIEQAMLDKEIDMAVHSMKDMPAVLPEGLVIGSIPKREDHRDVIISKGNIPFDQLKQGAVIGTSSLRRSAQLLAKRPDLEIKWIRGNIDTRVNKLEDSEYDAIILAAAGLYRLGWAQEVITEFIDDEVCVPAVGQGALSIECREADKELRDLLDQFTCKNTDRAVRAERAYLQKMEGGCQVPIAGYAYINDQDEVVMTGLVASPDGNIIYKEQLTGNNPEEVGNIVADRLTEKGGKALIDQVKRELENE
>NC_021171|3583108:3644239|3583108_3584248_-|WP_015595104.1|tRNA|DBSCAN-SWA
MSAITYELIKTCKQTGARLGRVHTPHGSFDTPAFMPVGTLATVKTMSPEDIKSMGAGIILSNTYHLWLRPGNEIVKEAGGLHKFMNWDRAILTDSGGFQVFSLSDFRKIEEEGVHFRNHLNGDKLFLSPEKAMQIQNDLGSDIMMAFDECPPFPATFEYMKKSVERTSRWAERCLTGHQRPNDQGLFGIVQGGEYEELRKLSAKDLVSLDFPGYAIGGLSVGEPKDVMNRVLEFTTPLLPTDKPRYLMGVGSPDSLIDGAIRGIDMFDCVLPTRIARNGTLMTSSGRLVVKNAKFARDFGPIDEECDCYTCKNYSRAYIRHLIRCDETFGIRLTTYHNLYFLLKLMEQVRQAIREDRLGDFKEEFFEKYGFNKPDAKNF
>NC_021171|3583108:3644239|3595273_3596569_-|WP_015595117.1|DBSCAN-SWA
MFVDQVKIYVKGGDGGNGMVAFRREKYVPKGGTAGGDGGKGGDVVFEVEEGLRTLMDFRYQRHFKAPRGEHGMSKNMHGRNSKDLIVKVPPGTVVSDEDTGEVIGDLTMHGQRAIIAKGGRGGRGNSRFATPSNPAPELSENGEPGRERNIMLELKLLADVGLVGYPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGMVETEDGRSFVLADLPGLIEGAHSGVGLGHQFLRHIERTRVIVHVIDMAATEGRDPYEDYLSINKELAQYNLRLMERPQIIVANKMDMPGAEENLKVFKEKLNDEYPVYPISAISRKGLRDLLFEIADKIEQTPEFPLIEEKEEEEVGLHRVVYKHEAEQDEFLITRESDGTFVISGEKVERLFKMTDFSRDESVQRFARQLRSMGIDEALRQKGAKDGDAVQLLNYEFEFIE
>NC_021171|3583108:3644239|3601291_3602065_-|WP_015595124.1|DBSCAN-SWA
MRSRADDVRKRIENRKKGRERQASQVHKRLLTVDDEEKHGFDRLPTYESGPNEENHPLFRKEVFLLKLLTSACLVLVMAILFRNHAASLDPARAFVKQSLDKDFQFAAVSNWYEGKFGKPLALFPVSDKKDTTNVATGQHYALPASGKILEDFDVSGQRITIETPKDAAVEAMNEGIIRFVGEKDGFGKTVIIQHADKSESWYGNLNNISVSLYEYIEKGKKVGTVTNTESGAKGAFYFAIKKDENFVDPIQVIQFE
>NC_021171|3583108:3644239|3600432_3601299_-|WP_015595123.1|DBSCAN-SWA
MNKLFELLKQVNVHPLLWLVIALAVLTARFLELSMLLIIIFIHELGHAVAASVFSWRIKKITLLPFGGVAEMDEHGNRPLFEEAIVILAGPFQHIWLIGGAFCFYELSWLSPEHYKLFLSYNMMVLLFNLLPIWPLDGGKLVFLLLSYYKSFPIAHRMTILVSLVCMVLFAGFTIVLMPNNLNVWIILAFLLFSLYHEWKQHRFIFMRFLLERYYGKRSDLRVLRPLKVAEDELVVHVLERFCRGCKHPIIIEENGKEKAILDENEILHAVFAEKLLTAKIRDLLYTY
>NC_021171|3583108:3644239|3613113_3614325_-|WP_015595138.1|DBSCAN-SWA
MARYKYSGRDRKGKKAGTINADSKREAIDKLREDGIRVLDLTEVKDAGLNKSISFGTPVKLQHMVIYLRQFATLIKAGVTIVEATNILAQQTESKKLRAALIDIENELRKGNPFSEAAEKHKKMFTSMFINLVKAGEAGGNMEETLERLAVFFEKQHTTRQKIKSALSYPIVIGIVAIGVVIFLLTSVVPTFVSMFADMGADLPAITKFVLNASEFMQSFWWVVILFVILIAIGFVGVKRNKKTKYYFDYVSLRMPLFGKMLQKAALARVTRTLSSLFSSGVPIMQALSIVENVVENEVIGKVLRASKDELAKGNSMTGPMLKHWAFPPLITQMIAIGENTGSLDSMLFKVAEFYEQEVENSTEKLKSLIEPLMIVFLASIVGVIVLSIMMPMFDMFKNVDKM
>NC_021171|3583108:3644239|3642970_3644239_-|WP_015595161.1|protease|DBSCAN-SWA
MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPKEIRDILDEYVIGQDQAKKSLSVAVYNHYKRINSNSKIDDVELSKSNICMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQSADYDVEKAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGQKVIGFGGTDNKQVDISQKELLGKVLPEDLLRFGLIPEFIGRLPVIASLEQLDESALIEILTKPKNALVKQYQKMLELDDVELEFEEKALTEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDISKCIITDETVIENSIPKLILEDGTIFDEKRKTSA
>NC_021171|3583108:3644239|3594792_3595248_-|WP_015595116.1|DBSCAN-SWA
MRHDKFDKKFFLVREDVLPEAMKKTLEAKEMIERGKAESVWDAVNRVDLSRSAFYKYRDTVFPFHTIVKERLITLFFQLEDRSGTLSKLLEVVAVSGCNVLTIHQTIPIQGRANVTLSLNVATMGIDLDELLTQLKRLEFVEKVEVLGSGA
>NC_021171|3583108:3644239|3628612_3629854_-|WP_015595149.1|DBSCAN-SWA
MSHEHQSFLRFSLEESVWFQRGQEVAELVSISLDPNITIVENDQYVAIRGSLELTGEYVRIKEDGLETEEDISAPKFIQSVEEREEGICEFTHRFPVDITIPNNRIQSINDIGVTVDSFDYAVPERSCLRLAAELTISGLYGEQQNVPTEEDQREPEEVQSYNEEVVNEDHLEQAEEIFLEIDQGEETPELQLLHRAGQTEEYEETQGYNPNFILSYPNETVSDELEEDESGLYEISQPFSAEAKKQPNANTAPSDYAWGIPIQSNQPPISKGPDFSFASQREDPLVPKAEVEYPQESSYEQPGAESNDTVVVIEVELDESSSSSSSEQIQIKKKKSSKKKSMSIAEFLGRKTENELQAKLKVCIVQHGETLDSLAERYALGVQQILKVNHLEATQDVYEGQVLYIPEPANSR
>NC_021171|3583108:3644239|3591194_3592817_-|WP_015595113.1|coat|DBSCAN-SWA
MKIHIVQKGDTLWKIAKKYGVNFEELKKMNSQLSNPDMIMPGMKIKVPTTGGTIKKEAPYGGAPATKISMGAKKEMPIKEQPFVKEQPMQMPIKEAPIAMPIKEAPIKEMPIKEMPIKEAPIAPYVPKMPQPIIPEIDINNYYMMNMANIQQPPPPPPQPQLPPKPVNILPVVKEECPEVPVQMPIQGGCEQPMYPCPPYIYPISPVLPGSGLPCPPYPQVAPCPPVQGPMPGYYGMPGVEGSAFVPHVHDESSSFMPNAPVQGFSEAQGFQPPGGYPAAYPQAAPFAQAAPFAQAPYGYPSYPQGPTVPVSPVLPGSGVPYGQIPYGQTPYGYGYPERMYPQMQGQTPVFPQYQAESADMMPYQQTQGLPTQYTTPPPFAGKADCGCGGPKAHVSGGVPYQGIPQFVQGTPPYSQGLNPYPPGVAPGQPGVVNPYPQGISPVQTGTSFYPQGGVPYQQGNVPIETGGPSYPQWSPAFEQGGVPIQQGMMPQGYPLPQGQIYSPPYAQQGLYMSPYGTGQMGGSPTSMPRQSDESSEYEA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015595104.1|3583108_3584248_-|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.4e-85	44.5
WP_015595105.1|3584273_3585302_-|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_015595106.1|3585346_3586348_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	8.1e-08	31.1
WP_015595107.1|3586432_3587041_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_015595108.1|3587197_3587725_+	hypothetical protein	NA	NA	NA	NA
WP_015595109.1|3587768_3588287_-	intercompartmental signaling factor BofC	NA	NA	NA	NA
WP_015595110.1|3588615_3589362_-	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_015595111.1|3589450_3590191_-	NAD(+) synthase	E3SLH5	Synechococcus_phage	1.2e-32	36.7
WP_144061606.1|3590227_3591211_-	phosphotransferase	NA	NA	NA	NA
WP_015595113.1|3591194_3592817_-|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_015595114.1|3593023_3593560_+	transcription repressor NadR	NA	NA	NA	NA
WP_015595115.1|3593890_3594742_-	prephenate dehydratase	NA	NA	NA	NA
WP_015595116.1|3594792_3595248_-	ACT domain-containing protein	NA	NA	NA	NA
WP_015595117.1|3595273_3596569_-	GTPase ObgE	NA	NA	NA	NA
WP_015595118.1|3596645_3597188_-	sporulation initiation phosphotransferase B	NA	NA	NA	NA
WP_015595119.1|3597585_3597876_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_015595120.1|3597888_3598221_-|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_015595121.1|3598232_3598541_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_015595122.1|3598927_3600403_-	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_015595123.1|3600432_3601299_-	M50 family metallopeptidase	NA	NA	NA	NA
WP_015595124.1|3601291_3602065_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_015595125.1|3602274_3603078_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_015595126.1|3603079_3603760_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_015595127.1|3603857_3604376_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_015595128.1|3604372_3605257_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_015595129.1|3605370_3606393_-	rod shape-determining protein	NA	NA	NA	NA
WP_187292196.1|3606552_3607224_-	DNA repair protein RadC	NA	NA	NA	NA
WP_015595131.1|3607290_3607863_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_015595132.1|3608064_3609207_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_015595133.1|3609379_3610156_-	pilus assembly protein PilO	NA	NA	NA	NA
WP_015595134.1|3610152_3610791_-	DUF3185 family protein	NA	NA	NA	NA
WP_015595135.1|3610793_3611786_-	pilus assembly protein PilM	NA	NA	NA	NA
WP_041580643.1|3611803_3612553_-	prepilin peptidase	NA	NA	NA	NA
WP_015595137.1|3612578_3613007_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_015595138.1|3613113_3614325_-	type II secretion system F family protein	NA	NA	NA	NA
WP_015595139.1|3614326_3615367_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_015595140.1|3615379_3617041_-	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_041580644.1|3617066_3618386_-	VanW family protein	NA	NA	NA	NA
WP_015595142.1|3618445_3619738_-	hypothetical protein	NA	NA	NA	NA
WP_041580646.1|3619993_3621334_-	hypothetical protein	NA	NA	NA	NA
WP_015595144.1|3621343_3621781_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_041580648.1|3621765_3622212_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_015595146.1|3622446_3623751_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_015595147.1|3623964_3626610_-|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	7.8e-159	42.1
WP_083935128.1|3627144_3627339_+	hypothetical protein	NA	NA	NA	NA
WP_015595148.1|3627480_3628533_-|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_015595149.1|3628612_3629854_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_015595150.1|3629982_3631272_-	glutamate-1-semialdehyde 2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	4.2e-09	26.1
WP_015595151.1|3631308_3632289_-	porphobilinogen synthase	NA	NA	NA	NA
WP_015595152.1|3632308_3633085_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_015595153.1|3633081_3634017_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_015595154.1|3634032_3634866_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_015595155.1|3634880_3636230_-|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_015595156.1|3636584_3637067_+	hypothetical protein	NA	NA	NA	NA
WP_015595157.1|3637505_3637763_+|transposase	transposase	NA	NA	NA	NA
WP_015595158.1|3638068_3638653_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_015595159.1|3638639_3640973_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	4.4e-182	44.6
WP_015595160.1|3641137_3642805_-|protease	ATP-dependent protease LonB	NA	NA	NA	NA
WP_015595161.1|3642970_3644239_-|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.1e-147	65.6