CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017769	Streptococcus pneumoniae ST556, complete sequence	2 crisprs	DEDDh,cas3,DinG	0	1	12	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_017769_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017769_1

1120403-1120506

Orphan

Consensus_repeat	Method
ATAGGGGATTTACCCACTACAAATATTATAGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017769_1

>merge|NC_017769|1|1120403-1120506|CRISPRCasFinder
ATAGGGGATTTACCCACTACAAATATTATAGAGCCCTTTTTTTCTACAATAAAATAGGCTCCATAATATCTATAGTGGATTTACCCACTACAAATATTATAGAG

>NC_017769|1|1|1120403-1120506|CRISPRCasFinder
ATAGGGGATTTACCCACTACAAATATTATAGAG	CCCTTTTTTTCTACAATAAAATAGGCTCCATAATATCT
ATAGTGGATTTACCCACTACAAATATTATAGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017769.2\|WP_000799053.1\|1115943_1116762_+\|NAD-kinase	unknown	unknown	gnl\|CDD\|235317
NC_017769.2\|WP_000863509.1\|1112042_1112390_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NC_017769.2\|WP_001284639.1\|1126930_1127206_+\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|259853
NC_017769.2\|WP_001210006.1\|1116758_1117655_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NC_017769.2\|WP_000592056.1\|1124994_1125843_-\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NC_017769.2\|WP_000639664.1\|1112394_1113510_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NC_017769.2\|WP_000681293.1\|1114591_1115161_-\|CYTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|226601
NC_017769.2\|WP_000653403.1\|1111095_1111737_-\|redox-sensing-transcriptional-repressor-Rex	unknown	unknown	gnl\|CDD\|225221
NC_017769.2\|WP_000109141.1\|1122152_1122467_+\|50S-ribosomal-protein-L21	unknown	unknown	gnl\|CDD\|235510
NC_017769.2\|WP_000584888.1\|1127632_1129534_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_017769.2\|WP_000587444.1\|1123984_1124902_+\|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl\|CDD\|235536
NC_017769.2\|WP_000981526.1\|1120565_1120865_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NC_017769.2\|WP_000161392.1\|1125984_1126824_+\|DegV-family-protein	unknown	unknown	gnl\|CDD\|273257
NC_017769.2\|WP_000916509.1\|1122843_1123137_+\|50S-ribosomal-protein-L27	unknown	unknown	gnl\|CDD\|235464
NC_017769.2\|WP_000509041.1\|1121266_1121965_+\|DUF1275-domain-containing-protein	unknown	unknown	gnl\|CDD\|226146
NC_017769.2\|WP_001283813.1\|1113519_1114479_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NC_017769.2\|WP_000613700.1\|1122482_1122827_+\|ribosomal-processing-cysteine-protease-Prp	unknown	unknown	gnl\|CDD\|225423
NC_017769.2\|WP_000451584.1\|1117698_1118673_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236609
NC_017769.2\|WP_000462487.1\|1111819_1112035_-\|DUF4649-family-protein	unknown	unknown	gnl\|CDD\|339492
NC_017769.2\|WP_000171676.1\|1115288_1115960_+\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232

Protein	Function_ID	Function_description	E-value
NC_017769.2\|WP_000799053.1\|1115943_1116762_+\|NAD-kinase	gnl\|CDD\|235317	PRK04885, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	9.83191e-171
NC_017769.2\|WP_000863509.1\|1112042_1112390_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	7.32693e-51
NC_017769.2\|WP_001284639.1\|1126930_1127206_+\|HU-family-DNA-binding-protein	gnl\|CDD\|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	4.4762e-40
NC_017769.2\|WP_001210006.1\|1116758_1117655_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	8.56983e-100
NC_017769.2\|WP_000592056.1\|1124994_1125843_-\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	4.30505e-85
NC_017769.2\|WP_000639664.1\|1112394_1113510_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	4.06104e-174
NC_017769.2\|WP_000681293.1\|1114591_1115161_-\|CYTH-domain-containing-protein	gnl\|CDD\|226601	COG4116, COG4116, Uncharacterized protein conserved in bacteria [Function unknown].	1.98141e-96
NC_017769.2\|WP_000653403.1\|1111095_1111737_-\|redox-sensing-transcriptional-repressor-Rex	gnl\|CDD\|225221	COG2344, COG2344, AT-rich DNA-binding protein [General function prediction only].	1.79308e-117
NC_017769.2\|WP_000109141.1\|1122152_1122467_+\|50S-ribosomal-protein-L21	gnl\|CDD\|235510	PRK05573, rplU, 50S ribosomal protein L21; Validated.	6.1021e-45
NC_017769.2\|WP_000584888.1\|1127632_1129534_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_017769.2\|WP_000587444.1\|1123984_1124902_+\|bifunctional-riboflavin-kinase/FAD-synthetase	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	8.98101e-130
NC_017769.2\|WP_000981526.1\|1120565_1120865_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	1.2452e-33
NC_017769.2\|WP_000161392.1\|1125984_1126824_+\|DegV-family-protein	gnl\|CDD\|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	3.43566e-110
NC_017769.2\|WP_000916509.1\|1122843_1123137_+\|50S-ribosomal-protein-L27	gnl\|CDD\|235464	PRK05435, rpmA, 50S ribosomal protein L27; Validated.	6.08512e-51
NC_017769.2\|WP_000509041.1\|1121266_1121965_+\|DUF1275-domain-containing-protein	gnl\|CDD\|226146	COG3619, COG3619, Predicted membrane protein [Function unknown].	8.49808e-63
NC_017769.2\|WP_001283813.1\|1113519_1114479_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NC_017769.2\|WP_000613700.1\|1122482_1122827_+\|ribosomal-processing-cysteine-protease-Prp	gnl\|CDD\|225423	COG2868, COG2868, Predicted ribosomal protein [Translation, ribosomal structure and biogenesis].	4.93617e-39
NC_017769.2\|WP_000451584.1\|1117698_1118673_+\|phosphate-acetyltransferase	gnl\|CDD\|236609	PRK09653, eutD, phosphotransacetylase.	0
NC_017769.2\|WP_000462487.1\|1111819_1112035_-\|DUF4649-family-protein	gnl\|CDD\|339492	pfam15507, DUF4649, Domain of unknown function (DUF4649). This family of Firmicute sequences has members that are annotated as ribose-phosphate pyrophosphokinase; however there is no evidence for this attribution. Member proteins are all shorter than 100 residues in length.	1.64583e-27
NC_017769.2\|WP_000171676.1\|1115288_1115960_+\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	7.7772e-102

>NC_017769.2|WP_000451584.1|1117698_1118673_+|phosphate-acetyltransferase
MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPVLLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVEDVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTERYLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVEATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYKMAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ
>NC_017769.2|WP_001210006.1|1116758_1117655_+|RluA-family-pseudouridine-synthase
MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQNATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNHSNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIEKRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLVDIRLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLDDGIQRQALHCHYLSFYHPFLEQDLQLESPLPDDFSNLITQLSTNTL
>NC_017769.2|WP_000799053.1|1115943_1116762_+|NAD-kinase
MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIVISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGARVSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVSTPTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRNDYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE
>NC_017769.2|WP_000171676.1|1115288_1115960_+|GTP-pyrophosphokinase-family-protein
MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTGRVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRIIQERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYKYQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDTDEEYR
>NC_017769.2|WP_000681293.1|1114591_1115161_-|CYTH-domain-containing-protein
MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFELREKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDELAKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQDFRQFLEKNQISYQKAPSKLVRFVKSMKNS
>NC_017769.2|WP_001283813.1|1113519_1114479_-|ribose-phosphate-diphosphokinase
MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQVNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDRIACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCDKGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKAILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDSVATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK
>NC_017769.2|WP_000639664.1|1112394_1113510_-|cysteine-desulfurase
MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKLLREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVLETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEIGQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFDSYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQYYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMYGANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG
>NC_017769.2|WP_000863509.1|1112042_1112390_-|DUF1831-domain-containing-protein
MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTRLLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMDSLVERGVFTKSER
>NC_017769.2|WP_000462487.1|1111819_1112035_-|DUF4649-family-protein
MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLTFRGKKVYQGLVGDLYRFLSHADFLHQN
>NC_017769.2|WP_000653403.1|1111095_1111737_-|redox-sensing-transcriptional-repressor-Rex
MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
>NC_017769.2|WP_000981526.1|1120565_1120865_-|YbaB/EbfC-family-nucleoid-associated-protein
MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
>NC_017769.2|WP_000509041.1|1121266_1121965_+|DUF1275-domain-containing-protein
MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLVAGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLSMLFASWQKKVKEKA
>NC_017769.2|WP_000109141.1|1122152_1122467_+|50S-ribosomal-protein-L21
MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVGGENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAINA
>NC_017769.2|WP_000613700.1|1122482_1122827_+|ribosomal-processing-cysteine-protease-Prp
MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINFINSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENYSEFVQTRVITEN
>NC_017769.2|WP_000916509.1|1122843_1123137_+|50S-ribosomal-protein-L27
MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
>NC_017769.2|WP_000587444.1|1123984_1124902_+|bifunctional-riboflavin-kinase/FAD-synthetase
MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAARKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQFASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKGKISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYMPADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLDRIRDMTKFDSVDQLVDQLKADEEVTRNWS
>NC_017769.2|WP_000592056.1|1124994_1125843_-|YitT-family-protein
MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITFYLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQGDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCILMLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDLGRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEGFTFEKE
>NC_017769.2|WP_000161392.1|1125984_1126824_+|DegV-family-protein
MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLKEEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQGASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGVSTLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITSLSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIRYHS
>NC_017769.2|WP_001284639.1|1126930_1127206_+|HU-family-DNA-binding-protein
MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQLIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK
>NC_017769.2|WP_000584888.1|1127632_1129534_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKSTLLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLRQMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKIAELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALLIVSHDRYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFVNRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAIGYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVGYYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKARLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVATHVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQKEVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAMLEWEELSDQV

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Crispr_ID: NC_017769_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017769_2

1449629-1449761

Orphan

Consensus_repeat	Method
ACTTCTGGTGTCGGTACATTTGGTG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_017769_2

>merge|NC_017769|2|1449629-1449761|CRISPRCasFinder
TGTTCTGGAACCGGTACTTCTGGTGTTGGAACAGCTGGAGTTGGTTGTACTGGCACTTCTGGTGTCGGTACATTTGGTGTTGGTTGCGCTGGCACAGGTTTAACCAGTACTTCTGGTGTCGGCACATTTGGTG

>NC_017769|2|2|1449629-1449761|CRISPRCasFinder
TGTTCTGGAACCGGTACTTCTGGTG	TTGGAACAGCTGGAGTTGGTTGTACTGGC
ACTTCTGGTGTCGGTACATTTGGTG	TTGGTTGCGCTGGCACAGGTTTAACCAGT
ACTTCTGGTGTCGGCACATTTGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017769.2\|WP_161801414.1\|1444943_1446290_-\|asparagine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235176
NC_017769.2\|WP_000412220.1\|1459457_1459868_-\|peptide-deformylase	unknown	unknown	gnl\|CDD\|181704
NC_017769.2\|WP_000777792.1\|1446663_1447851_-\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|235596
NC_017769.2\|WP_000822863.1\|1457850_1459446_-\|hypothetical-protein	unknown	unknown	unknown
NC_017769.2\|WP_001138814.1\|1466982_1468167_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|237339
NC_017769.2\|WP_000813916.1\|1463787_1464972_+\|CDF-family-manganese-efflux-transporter-MntE	unknown	unknown	gnl\|CDD\|223131
NC_017769.2\|WP_001245190.1\|1455278_1456763_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NC_017769.2\|WP_000747253.1\|1447847_1448336_-\|DUF5590-domain-containing-protein	unknown	unknown	gnl\|CDD\|227656
NC_017769.2\|WP_000508269.1\|1457620_1457785_-\|YczI-family-protein	unknown	unknown	gnl\|CDD\|315732
NC_017769.2\|WP_001151785.1\|1444500_1444791_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
NC_017769.2\|WP_000039614.1\|1448656_1449205_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223508
NC_017769.2\|WP_000032458.1\|1460787_1463484_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319781
NC_017769.2\|WP_001279133.1\|1465114_1466986_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_017769.2\|WP_000565216.1\|1446446_1446671_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319923
NC_017769.2\|WP_000609607.1\|1444018_1444489_-\|single-stranded-DNA-binding-protein-SsbA	unknown	unknown	gnl\|CDD\|180915
NC_017769.2\|WP_001277403.1\|1459983_1460775_-\|glutathione-dependent-disulfide-bond-oxidoreductase	unknown	unknown	gnl\|CDD\|183298
NC_017769.2\|WP_000068664.1\|1443747_1443987_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
NC_017769.2\|WP_000339034.1\|1442052_1443453_-\|bifunctional-Cof-type-HAD-IIB-family-hydrolase/peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NC_017769.2\|WP_000689600.1\|1441691_1442051_-\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|180908
NC_017769.2\|WP_000697775.1\|1456813_1457542_-\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999

Protein	Function_ID	Function_description	E-value
NC_017769.2\|WP_161801414.1\|1444943_1446290_-\|asparagine--tRNA-ligase	gnl\|CDD\|235176	PRK03932, asnC, asparaginyl-tRNA synthetase; Validated.	0
NC_017769.2\|WP_000412220.1\|1459457_1459868_-\|peptide-deformylase	gnl\|CDD\|181704	PRK09218, PRK09218, peptide deformylase; Validated.	5.2801e-91
NC_017769.2\|WP_000777792.1\|1446663_1447851_-\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NC_017769.2\|WP_001138814.1\|1466982_1468167_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|237339	PRK13299, PRK13299, tRNA CCA-pyrophosphorylase; Provisional.	0
NC_017769.2\|WP_000813916.1\|1463787_1464972_+\|CDF-family-manganese-efflux-transporter-MntE	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	3.68565e-101
NC_017769.2\|WP_001245190.1\|1455278_1456763_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	2.08116e-76
NC_017769.2\|WP_000747253.1\|1447847_1448336_-\|DUF5590-domain-containing-protein	gnl\|CDD\|227656	COG5353, COG5353, Uncharacterized protein conserved in bacteria [Function unknown].	3.22216e-58
NC_017769.2\|WP_000508269.1\|1457620_1457785_-\|YczI-family-protein	gnl\|CDD\|315732	pfam13129, DUF3953, Protein of unknown function (DUF3953). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 47 and 76 amino acids in length.	0.000993842
NC_017769.2\|WP_001151785.1\|1444500_1444791_-\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	1.40041e-37
NC_017769.2\|WP_000039614.1\|1448656_1449205_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	1.09403e-32
NC_017769.2\|WP_000032458.1\|1460787_1463484_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_017769.2\|WP_001279133.1\|1465114_1466986_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_017769.2\|WP_000565216.1\|1446446_1446671_-\|hypothetical-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.22811e-09
NC_017769.2\|WP_000609607.1\|1444018_1444489_-\|single-stranded-DNA-binding-protein-SsbA	gnl\|CDD\|180915	PRK07275, PRK07275, single-stranded DNA-binding protein; Provisional.	1.66017e-101
NC_017769.2\|WP_001277403.1\|1459983_1460775_-\|glutathione-dependent-disulfide-bond-oxidoreductase	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	0
NC_017769.2\|WP_000068664.1\|1443747_1443987_-\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	3.32721e-37
NC_017769.2\|WP_000339034.1\|1442052_1443453_-\|bifunctional-Cof-type-HAD-IIB-family-hydrolase/peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	5.47265e-62
NC_017769.2\|WP_000689600.1\|1441691_1442051_-\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|180908	PRK07252, PRK07252, S1 RNA-binding domain-containing protein.	1.98721e-79
NC_017769.2\|WP_000697775.1\|1456813_1457542_-\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	5.15942e-96

>NC_017769.2|WP_000039614.1|1448656_1449205_+|NAD(P)H-dependent-oxidoreductase
MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALPLFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDTRGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKLVLEETVLNSLEKQAQDLVEAIQ
>NC_017769.2|WP_000747253.1|1447847_1448336_-|DUF5590-domain-containing-protein
MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQTAKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQLNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKEGL
>NC_017769.2|WP_000777792.1|1446663_1447851_-|pyridoxal-phosphate-dependent-aminotransferase
MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTTPKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKYSLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEVARTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTPISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQYAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAMEMKGYTDVTDFTTAILEESEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGSEND
>NC_017769.2|WP_000565216.1|1446446_1446671_-|hypothetical-protein
MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPNSPHPGGDFWLTQGTQDPVHFAFLAENKEEV
>NC_017769.2|WP_161801414.1|1444943_1446290_-|asparagine--tRNA-ligase
MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGFMKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPTFVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP
>NC_017769.2|WP_001151785.1|1444500_1444791_-|30S-ribosomal-protein-S6
MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWEKRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA
>NC_017769.2|WP_000609607.1|1444018_1444489_-|single-stranded-DNA-binding-protein-SsbA
MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQMLESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF
>NC_017769.2|WP_000068664.1|1443747_1443987_-|30S-ribosomal-protein-S18
MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
>NC_017769.2|WP_000339034.1|1442052_1443453_-|bifunctional-Cof-type-HAD-IIB-family-hydrolase/peptidylprolyl-isomerase
MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLREKGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIGKSDVEEYISWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFEDKGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDGLNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQVDIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMIQGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLPYSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAMDKPVEDVVIETIEIED
>NC_017769.2|WP_000689600.1|1441691_1442051_-|S1-RNA-binding-domain-containing-protein
MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENIHETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRRMLPIWTGEALHYLKKKK
>NC_017769.2|WP_001245190.1|1455278_1456763_+|helix-turn-helix-domain-containing-protein
MRNLLSTKVQRQLRLMENLIQNRNWMKLHELAEKLGCTERILKSDLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLPIYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSERYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFIDLPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEFFNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPILFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLSTQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDYDIIVSNFYIPGITKKFICRNHLSIINLVNHLNTLSNEIHLSNTL
>NC_017769.2|WP_000697775.1|1456813_1457542_-|peroxide-stress-protein-YaaA
MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLESFYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHVFITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSSEFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARRLNFAGFVYREDLSQPQGLVFVKEV
>NC_017769.2|WP_000508269.1|1457620_1457785_-|YczI-family-protein
MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALVLVAVWLGWPK
>NC_017769.2|WP_000822863.1|1457850_1459446_-|hypothetical-protein
MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILFGFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSMFQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAADTYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYSDSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVIILDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTNGYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEGAVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEMLSKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPYLENGKTFEGQVGKDNYLKTFKLR
>NC_017769.2|WP_000412220.1|1459457_1459868_-|peptide-deformylase
MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGLAANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRLAYRDSKWQEQTITLTGFPAQICQHELDHLEGRII
>NC_017769.2|WP_001277403.1|1459983_1460775_-|glutathione-dependent-disulfide-bond-oxidoreductase
MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQLYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPALLDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFGHFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLVQGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK
>NC_017769.2|WP_000032458.1|1460787_1463484_-|cation-translocating-P-type-ATPase
MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHNELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAFGVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLRLIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVVNTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKNPLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIASDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIGDPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGAPDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLTSEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGIIDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAMTGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNIQKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGVMNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALTMAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGIFHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI
>NC_017769.2|WP_000813916.1|1463787_1464972_+|CDF-family-manganese-efflux-transporter-MntE
MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVADGFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRDTIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDAVTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLEDYQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERFGVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQMDKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETKKE
>NC_017769.2|WP_001279133.1|1465114_1466986_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTTLLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIREYELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGLRRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDALSTRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQARATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQDFNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLDESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLLKLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAFEDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASIEGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS
>NC_017769.2|WP_001138814.1|1466982_1468167_-|CCA-tRNA-nucleotidyltransferase
MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSLLKSWKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQSLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLREKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017769_1	1.1\|1120436\|38\|NC_017769\|CRISPRCasFinder	1120436-1120473	38	KY065475	Streptococcus phage IPP35, complete genome	23044-23081	4	0.895
NC_017769_1	1.1\|1120436\|38\|NC_017769\|CRISPRCasFinder	1120436-1120473	38	MK448453	Streptococcus satellite phage Javan360, complete genome	13985-14022	5	0.868

1. spacer 1.1|1120436|38|NC_017769|CRISPRCasFinder matches to KY065475 (Streptococcus phage IPP35, complete genome) position: , mismatch: 4, identity: 0.895

ccctttttttctacaataaaataggctccataatatct	CRISPR spacer
gactttttttctacacaaaaataggctccataatatct	Protospacer
  *************  *********************

2. spacer 1.1|1120436|38|NC_017769|CRISPRCasFinder matches to MK448453 (Streptococcus satellite phage Javan360, complete genome) position: , mismatch: 5, identity: 0.868

ccctttttttctacaataaaataggctccataatatct	CRISPR spacer
gactttttttctacaacaaaataggctccataatattc	Protospacer
  **************.*******************..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

13046 : 110163

Streptococcus_phage(75.36%)

integrase,tRNA,bacteriocin,holin,terminase,transposase,tail,portal,protease,capsid

attL 10839:10854|attR 59731:59746

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
10839:10854	attL	NA	NA	NA	NA
WP_000424684.1\|13046_13652_-	Rha family transcriptional regulator	A0A192Y918	Salmonella_phage	6.8e-18	34.1
WP_014678319.1\|13673_14051_-	hypothetical protein	NA	NA	NA	NA
WP_001241280.1\|14125_14317_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001814778.1\|14520_15237_+	helix-turn-helix domain-containing protein	A0A1S5SFG5	Streptococcus_phage	2.6e-77	63.0
WP_000666926.1\|15255_15924_+	zinc ribbon domain-containing protein	A0A141DZS3	Streptococcus_phage	8.4e-78	74.1
WP_000222518.1\|16062_16731_+	Fic family protein	D7RWK9	Brochothrix_phage	9.2e-08	24.6
WP_000255647.1\|17194_17653_-	hypothetical protein	A0A1X9I5V5	Streptococcus_phage	5.6e-25	46.0
WP_000417039.1\|19075_19381_+	protein rep	NA	NA	NA	NA
WP_000422980.1\|19485_20046_+	multidrug DMT transporter	A0A1W6JPJ7	Morganella_phage	4.6e-21	56.1
WP_000704676.1\|20481_21648_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	2.0e-103	51.5
WP_001218707.1\|21767_22883_+	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_000163933.1\|22953_23523_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000258080.1\|23523_27033_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_001234978.1\|27090_27357_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_000041909.1\|27349_27718_+	septum formation initiator family protein	NA	NA	NA	NA
WP_001224749.1\|27837_29106_+	serine hydrolase	NA	NA	NA	NA
WP_001208988.1\|29102_30380_+\|tRNA	tRNA lysidine(34) synthetase TilS	A7K9Y8	Acanthocystis_turfacea_chlorella_virus	2.5e-06	24.1
WP_000892184.1\|30383_30926_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	2.7e-10	28.9
WP_000744557.1\|30941_32900_+\|protease	ATP-dependent zinc metalloprotease FtsH	H8ZJI5	Ostreococcus_tauri_virus	3.2e-109	45.8
WP_000588897.1\|33021_33501_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_000939544.1\|40356_40593_+	hypothetical protein	NA	NA	NA	NA
WP_000205044.1\|40823_42110_+	adenylosuccinate synthase	L7Y4J5	Megavirus	2.7e-72	37.1
WP_000291879.1\|42310_42778_+	nucleoside deaminase	NA	NA	NA	NA
WP_000266852.1\|42986_44129_-\|integrase	site-specific integrase	U4KJ82	Streptococcus_phage	1.4e-210	99.2
WP_001020945.1\|44247_44598_-	hypothetical protein	Q9MBY8	Streptococcus_phage	7.3e-57	100.0
WP_000153672.1\|44885_45242_-	helix-turn-helix transcriptional regulator	A0A1S5SDR1	Streptococcus_phage	4.2e-60	100.0
WP_000638668.1\|45517_45703_+	helix-turn-helix transcriptional regulator	A0A1S5SDM7	Streptococcus_phage	1.0e-25	98.4
WP_001004041.1\|45704_46403_+	phage antirepressor KilAC domain-containing protein	A0A1S5SDI0	Streptococcus_phage	7.6e-130	100.0
WP_001811944.1\|46662_46899_-	hypothetical protein	A0A1S5SDG8	Streptococcus_phage	7.9e-39	100.0
WP_000450962.1\|47576_47843_+	hypothetical protein	A0A1S5SDB5	Streptococcus_phage	1.5e-41	100.0
WP_001134283.1\|47926_48379_+	hypothetical protein	A0A1S5SDE0	Streptococcus_phage	8.5e-82	100.0
WP_000774580.1\|48384_49086_+	ERF family protein	A0A1S5SEM6	Streptococcus_phage	1.5e-117	100.0
WP_000237815.1\|49088_50081_+	DUF1351 domain-containing protein	A0A1S5SDA5	Streptococcus_phage	5.5e-174	100.0
WP_001203349.1\|50102_50279_+	hypothetical protein	A0A1S5SE71	Streptococcus_phage	4.8e-25	100.0
WP_000609578.1\|50268_50844_+	single-stranded DNA-binding protein	A0A1S5SDP3	Streptococcus_phage	2.0e-88	100.0
WP_000670027.1\|50869_52108_+	DNA cytosine methyltransferase	A0A1S5SDI9	Streptococcus_phage	5.5e-224	100.0
WP_000161129.1\|52142_52346_+	hypothetical protein	A0A1S5SDE4	Streptococcus_phage	4.4e-30	100.0
WP_001286809.1\|52569_52782_+	hypothetical protein	A0A1S5SEA6	Streptococcus_phage	1.7e-32	100.0
WP_000667209.1\|52792_53194_+	hypothetical protein	U4KJA0	Streptococcus_phage	1.9e-72	100.0
WP_000573750.1\|53195_53402_+	hypothetical protein	A0A1S5SDU5	Streptococcus_phage	1.1e-31	100.0
WP_000969685.1\|53450_53768_+	hypothetical protein	A0A1S5SDC6	Streptococcus_phage	3.5e-58	100.0
WP_001021768.1\|53769_54285_+	DUF1642 domain-containing protein	A0A1S5SDB8	Streptococcus_phage	9.0e-96	100.0
WP_000160161.1\|54285_54498_+	hypothetical protein	A0A1S5SDS6	Streptococcus_phage	8.1e-35	100.0
WP_001247149.1\|54494_54866_+	hypothetical protein	A0A1S5SDQ3	Streptococcus_phage	8.5e-56	100.0
WP_000194856.1\|54886_55180_+	hypothetical protein	A0A1S5SDK0	Streptococcus_phage	9.4e-50	100.0
WP_000162611.1\|55179_55572_+	hypothetical protein	A0A1S5SED1	Streptococcus_phage	7.1e-69	100.0
WP_000425574.1\|55637_56732_+	DUF4417 domain-containing protein	A0A1S5SDI7	Streptococcus_phage	1.4e-202	100.0
WP_000057535.1\|56712_57459_+	hypothetical protein	A0A1S5SDN7	Streptococcus_phage	2.9e-135	100.0
WP_001136855.1\|57662_58118_+	hypothetical protein	A0A1C9LX59	Streptococcus_phage	5.0e-74	100.0
WP_000143806.1\|58107_59418_+\|terminase	PBSX family phage terminase large subunit	U4KJA9	Streptococcus_phage	1.8e-257	100.0
WP_000051858.1\|59430_60999_+\|portal	phage portal protein	A0A141E1J7	Streptococcus_phage	5.4e-301	99.4
59731:59746	attR	NA	NA	NA	NA
WP_000169861.1\|60985_61159_+	hypothetical protein	A0A1S5SEA5	Streptococcus_phage	1.3e-22	100.0
WP_000730217.1\|61201_62353_+\|capsid	phage minor capsid protein	A0A1S5SEP6	Streptococcus_phage	1.9e-218	100.0
WP_000896122.1\|62491_63055_+	phage scaffolding protein	A0A1S5SEM4	Streptococcus_phage	9.9e-80	100.0
WP_001139823.1\|63072_63954_+	hypothetical protein	A0A1S5SDL2	Streptococcus_phage	3.6e-161	100.0
WP_001240344.1\|63964_64198_+	hypothetical protein	A0A1S5SEE1	Streptococcus_phage	6.8e-35	100.0
WP_000221836.1\|64240_64633_+	hypothetical protein	A0A1S5SEH1	Streptococcus_phage	5.3e-64	100.0
WP_000565934.1\|64622_64994_+	hypothetical protein	A0A1S5SDP6	Streptococcus_phage	1.5e-63	100.0
WP_000020371.1\|64993_65338_+	hypothetical protein	A0A1S5SDE2	Streptococcus_phage	8.5e-58	100.0
WP_001208881.1\|65337_65745_+\|capsid	phage capsid protein	A0A1S5SEE3	Streptococcus_phage	3.2e-72	100.0
WP_000198229.1\|65741_66191_+	hypothetical protein	A0A1S5SDE5	Streptococcus_phage	4.9e-82	100.0
WP_000129839.1\|66255_66744_+	hypothetical protein	A0A1S5SDD9	Streptococcus_phage	7.5e-84	100.0
WP_000062053.1\|66756_67326_+	hypothetical protein	A0A1S5SCA6	Streptococcus_phage	3.2e-102	99.5
WP_001279483.1\|67318_70600_+	tape measure protein	A0A1S5SDS2	Streptococcus_phage	0.0e+00	100.0
WP_000161549.1\|70596_72111_+\|tail	phage tail family protein	A0A1S5SEJ1	Streptococcus_phage	2.0e-300	100.0
WP_053039873.1\|72112_78583_+\|tail	phage tail protein	A0A1S5SDH6	Streptococcus_phage	0.0e+00	70.9
WP_000159969.1\|78594_80673_+	hypothetical protein	A0A1S5SDL3	Streptococcus_phage	0.0e+00	100.0
WP_000922100.1\|80732_80996_+	hypothetical protein	A0A1S5SEN3	Streptococcus_phage	1.8e-39	100.0
WP_000687457.1\|81005_81422_+\|holin	phage holin family protein	A0A1S5SEC7	Streptococcus_phage	4.9e-68	100.0
WP_001186225.1\|81425_81758_+\|holin	phage holin	A0A1S5SDI2	Streptococcus_phage	4.3e-51	100.0
WP_000350491.1\|81761_82718_+	N-acetylmuramoyl-L-alanine amidase LytA	A0A1S5SDF6	Streptococcus_phage	6.1e-146	100.0
WP_000701992.1\|82997_83441_+	dUTP diphosphatase	Q2WG49	Clostridium_botulinum_D_phage	2.1e-29	47.3
WP_000691236.1\|83442_83958_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_073076903.1\|83971_85333_+	DNA repair protein RadA	NA	NA	NA	NA
WP_001809263.1\|85405_85903_+	carbonic anhydrase	NA	NA	NA	NA
WP_000749768.1\|85927_86743_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_000010163.1\|86887_87856_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	4.0e-44	34.7
WP_000492735.1\|88399_88633_-	hypothetical protein	NA	NA	NA	NA
WP_001816159.1\|88625_88742_-	hypothetical protein	NA	NA	NA	NA
WP_060544779.1\|88956_89307_-\|transposase	PD-(D/E)XK nuclease family transposase	NA	NA	NA	NA
WP_000358436.1\|89562_92196_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	3.4e-58	30.3
WP_000076479.1\|92280_92718_+	CoA-binding protein	NA	NA	NA	NA
WP_000009178.1\|92900_93911_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_000366375.1\|94059_95229_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000616166.1\|95225_95996_+	DNA repair protein RecO	NA	NA	NA	NA
WP_000717456.1\|95992_96985_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_000136447.1\|96990_97224_+	acyl carrier protein	A0A2I7RIC8	Vibrio_phage	3.3e-05	40.6
WP_001093071.1\|97762_97993_+\|bacteriocin	bacteriocin-like peptide BlpU	NA	NA	NA	NA
WP_000668293.1\|98707_100861_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	1.0e-44	28.0
WP_000801629.1\|100873_102223_+	HlyD family secretion protein	NA	NA	NA	NA
WP_000043313.1\|102392_103100_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	1.3e-41	39.2
WP_000361166.1\|103301_107027_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	6.2e-37	25.5
WP_000220633.1\|107119_108562_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.7e-55	35.1
WP_000182580.1\|108598_109621_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	7.3e-65	44.2
WP_000717501.1\|109617_110163_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.7e-24	35.0

DBSCAN-SWA_2

152026 : 193464

Streptococcus_phage(50.0%)

transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001821265.1\|152026_153373_+\|transposase	IS1380-like element ISSpn5 family transposase	A0A1X9I6F6	Streptococcus_phage	4.5e-78	40.0
WP_001257240.1\|154444_154642_+	hypothetical protein	NA	NA	NA	NA
WP_000808434.1\|154878_155943_-	membrane protein	NA	NA	NA	NA
WP_001229057.1\|156005_156917_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_000198675.1\|156909_157503_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000273854.1\|157489_157816_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_000744897.1\|157954_159121_-	CynX/NimT family MFS transporter	NA	NA	NA	NA
WP_000096202.1\|159178_160336_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_001035700.1\|160377_162228_+	polysaccharide biosynthesis protein	A0A2P1ELS8	Moumouvirus	7.6e-28	30.5
WP_025168890.1\|162123_162528_-	hypothetical protein	NA	NA	NA	NA
WP_000200898.1\|162577_163210_-	HAD family hydrolase	NA	NA	NA	NA
WP_000500038.1\|163231_164104_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	NA	NA	NA	NA
WP_000838912.1\|164112_164784_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit beta	NA	NA	NA	NA
WP_000836450.1\|165025_165613_+	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	1.6e-27	56.7
WP_001189285.1\|165664_165985_-	hypothetical protein	NA	NA	NA	NA
WP_073077611.1\|166391_166685_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000723961.1\|166739_168848_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000571330.1\|168844_169486_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.3e-23	34.8
WP_001038474.1\|169692_170499_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_099516442.1\|170464_170935_+	argininosuccinate synthase	NA	NA	NA	NA
WP_001189278.1\|171224_171545_-	hypothetical protein	NA	NA	NA	NA
WP_000424418.1\|172303_172672_+\|bacteriocin	SP_0115 family bacteriocin-like peptide	NA	NA	NA	NA
WP_001268157.1\|173071_173935_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000915345.1\|174400_174739_+	peptidase C39	NA	NA	NA	NA
WP_000973716.1\|175366_175579_+	hypothetical protein	NA	NA	NA	NA
WP_000424467.1\|175994_176357_+	hypothetical protein	NA	NA	NA	NA
WP_000356083.1\|176337_176583_+	hypothetical protein	NA	NA	NA	NA
WP_001814711.1\|176739_177798_+	hypothetical protein	NA	NA	NA	NA
WP_000792250.1\|178113_179091_+	hypothetical protein	NA	NA	NA	NA
WP_000424474.1\|179467_179842_+\|bacteriocin	SPH_0224 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000619753.1\|180049_180952_+	hypothetical protein	NA	NA	NA	NA
WP_000424439.1\|181007_181361_+	hypothetical protein	NA	NA	NA	NA
WP_000072924.1\|181357_182086_+	hypothetical protein	NA	NA	NA	NA
WP_000770314.1\|183220_183460_+	hypothetical protein	M1Q0Z8	Streptococcus_phage	7.2e-16	54.1
WP_000058768.1\|183478_183724_+	hypothetical protein	M1Q0Z8	Streptococcus_phage	1.3e-15	53.4
WP_001035384.1\|184011_186186_+	pneumococcal surface protein A	NA	NA	NA	NA
WP_001282969.1\|186586_187708_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000193634.1\|187848_188304_+	NUDIX hydrolase	NA	NA	NA	NA
WP_000220964.1\|188313_190227_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_000331983.1\|190579_192259_-	ribonuclease J	NA	NA	NA	NA
WP_000639589.1\|192260_192494_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_000282479.1\|192773_192989_+	hypothetical protein	NA	NA	NA	NA
WP_000974047.1\|193311_193464_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibB	NA	NA	NA	NA

DBSCAN-SWA_3

239847 : 247673

Streptococcus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001107589.1\|239847_240561_-	helix-turn-helix domain-containing protein	Q708R9	Streptococcus_phage	2.0e-16	51.9
WP_000090006.1\|240713_240944_+	helix-turn-helix transcriptional regulator	X2KUC2	Streptococcus_phage	3.7e-09	47.0
WP_000424665.1\|240959_241586_+	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	2.1e-30	40.8
WP_000141100.1\|241957_242410_+	hypothetical protein	NA	NA	NA	NA
WP_000174331.1\|242406_242607_+	hypothetical protein	NA	NA	NA	NA
WP_001003774.1\|242608_242824_+	hypothetical protein	NA	NA	NA	NA
WP_000058832.1\|242820_243162_+	hypothetical protein	NA	NA	NA	NA
WP_000492137.1\|243154_243436_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	7.9e-30	67.8
WP_000158192.1\|243570_244437_+	primase alpha helix C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	8.2e-126	75.0
WP_000434359.1\|244489_245959_+	DNA primase family protein	Q9AZI5	Lactococcus_phage	2.3e-64	35.0
WP_000865230.1\|246311_246479_+	hypothetical protein	NA	NA	NA	NA
WP_000173130.1\|246562_247093_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	2.8e-36	48.7
WP_000811078.1\|247163_247673_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	5.8e-47	53.9

DBSCAN-SWA_4

387790 : 442595

Streptococcus_phage(23.08%)

transposase,protease,holin,integrase

attL 390637:390650|attR 443977:443990

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001063396.1\|387790_389896_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	1.0e-116	37.6
WP_000032550.1\|390190_390673_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
390637:390650	attL	NA	NA	NA	NA
WP_000743620.1\|390767_392252_-	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_001156769.1\|392404_394012_+	alpha-glucosidase	NA	NA	NA	NA
WP_033604964.1\|394176_394344_+	S-ribosylhomocysteinase	NA	NA	NA	NA
WP_000091077.1\|395431_396877_+	capsular polysaccharide biosynthesis protein Cps4A	A0A1X9I5X1	Streptococcus_phage	3.6e-134	60.1
WP_000565348.1\|396878_397610_+	tyrosine-protein phosphatase CpsB	NA	NA	NA	NA
WP_000664166.1\|397618_398311_+	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	4.3e-61	55.9
WP_001142521.1\|398320_399004_+	polysaccharide biosynthesis tyrosine autokinase CpsD	A0A1X9I5D6	Streptococcus_phage	1.3e-70	60.9
WP_000343581.1\|399019_400387_+	sugar transferase	NA	NA	NA	NA
WP_001205625.1\|400390_401134_+	WecB/TagA/CpsF family glycosyltransferase	NA	NA	NA	NA
WP_001076786.1\|401130_401955_+	LicD family protein	A0A1V0SD50	Indivirus	1.8e-05	38.7
WP_000458863.1\|401956_402835_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_000120848.1\|402835_404173_+	oligosaccharide repeat unit polymerase	NA	NA	NA	NA
WP_001092842.1\|404195_405617_+	hypothetical protein	NA	NA	NA	NA
WP_000723326.1\|405680_406769_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.0e-27	30.3
WP_000676118.1\|406807_407677_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	9.2e-101	63.2
WP_000131463.1\|407677_408274_+	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	H9NC63	Sphingomonas_phage	3.0e-10	32.8
WP_000141500.1\|408283_409333_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.3e-72	44.2
WP_000600898.1\|409398_410250_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	4.3e-26	35.4
WP_000842571.1\|411718_413701_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001032472.1\|414001_419305_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_001041857.1\|419470_421630_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_000248773.1\|421626_422223_-	Holliday junction resolvase RecU	A0A1L2JY30	Aeribacillus_phage	1.5e-17	33.9
WP_000179553.1\|422289_422817_+	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_000200644.1\|422886_423228_+	cell division regulator GpsB	NA	NA	NA	NA
WP_000711398.1\|423713_424871_+	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_000039290.1\|424883_426278_+	mid-cell-anchored protein MapZ	NA	NA	NA	NA
WP_000158792.1\|426353_427778_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.7e-41	29.6
WP_000518011.1\|427789_428479_+	response regulator transcription factor	NA	NA	NA	NA
WP_000698035.1\|428576_429539_+\|holin	choline-binding protein CbpC	NA	NA	NA	NA
WP_000771128.1\|429557_430556_+\|holin	choline-binding protein CbpJ	NA	NA	NA	NA
WP_000765677.1\|430673_431906_-	MFS transporter	NA	NA	NA	NA
WP_000196972.1\|433436_433766_+\|transposase	transposase	NA	NA	NA	NA
WP_000163329.1\|433887_434766_+	mevalonate kinase	NA	NA	NA	NA
WP_000373456.1\|434747_435701_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
WP_000562377.1\|435687_436695_+	phosphomevalonate kinase	NA	NA	NA	NA
WP_000210628.1\|436678_437689_+	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_001224634.1\|437766_438465_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_000743662.1\|438461_439457_+	sensor histidine kinase	NA	NA	NA	NA
WP_000698433.1\|439470_440103_+	response regulator transcription factor	NA	NA	NA	NA
WP_075218746.1\|440270_440582_+	DNA alkylation repair protein	NA	NA	NA	NA
WP_000754506.1\|441022_441937_+\|protease	serine protease	NA	NA	NA	NA
WP_000378123.1\|442235_442595_+\|integrase	tyrosine-type recombinase/integrase	C9E2L6	Enterococcus_phage	1.4e-18	41.0
443977:443990	attR	NA	NA	NA	NA

DBSCAN-SWA_5

514174 : 577068

Klosneuvirus(18.18%)

protease,transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001810089.1\|514174_514345_-\|transposase	transposase	NA	NA	NA	NA
WP_000628994.1\|514998_516222_-	ROK family transcriptional regulator	NA	NA	NA	NA
WP_001059636.1\|516388_517711_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_000236908.1\|517712_519599_+	DUF4838 domain-containing protein	NA	NA	NA	NA
WP_000836781.1\|519766_520111_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_000429402.1\|520120_521533_+	6-phospho-beta-galactosidase	NA	NA	NA	NA
WP_000359753.1\|521601_523281_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_001809506.1\|523406_524846_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000691685.1\|524849_526199_-	Trk system potassium transporter TrkA	NA	NA	NA	NA
WP_001063601.1\|526386_527235_+	S-adenosyl-l-methionine hydroxide adenosyltransferase family protein	NA	NA	NA	NA
WP_000403169.1\|527249_527798_+	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_000693286.1\|527804_528062_+	hypothetical protein	NA	NA	NA	NA
WP_000656522.1\|528163_529846_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.4e-19	34.4
WP_001148103.1\|529830_530661_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000181380.1\|530853_531357_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_000185835.1\|531809_532373_+	ECF transporter S component	NA	NA	NA	NA
WP_000678704.1\|532386_533013_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000867296.1\|533039_533429_+	hypothetical protein	NA	NA	NA	NA
WP_000333653.1\|533433_533883_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000418402.1\|534010_534598_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_000105242.1\|534987_536595_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.9e-142	47.0
WP_000026631.1\|537153_538785_-	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_000795202.1\|539073_544014_+	bacterial Ig-like domain-containing protein	NA	NA	NA	NA
WP_001096743.1\|544103_545300_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_000119900.1\|545435_545963_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_000659547.1\|546039_546396_+	transcriptional repressor GlnR	NA	NA	NA	NA
WP_001122904.1\|546432_547779_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_001808898.1\|547874_547994_-	hypothetical protein	NA	NA	NA	NA
WP_000410535.1\|547958_548108_+	hypothetical protein	NA	NA	NA	NA
WP_001220743.1\|548560_549841_+	restriction endonuclease subunit S	A0A1V0SKS6	Klosneuvirus	5.3e-12	29.8
WP_000651177.1\|549897_550695_+	tyrosine-type DNA invertase PsrA	A0A0H4TI16	Erysipelothrix_phage	1.3e-21	28.7
WP_000240090.1\|550705_551314_+	restriction endonuclease subunit S	A0A1V0SLK8	Klosneuvirus	3.9e-13	30.1
WP_000187223.1\|551261_552827_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000029054.1\|552826_554290_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_000229085.1\|554302_556636_-	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	2.0e-25	28.9
WP_001088687.1\|557243_557753_+	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_000255769.1\|557916_558951_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_000046031.1\|558977_559502_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_000034662.1\|559981_561805_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.3e-133	47.2
WP_000115730.1\|561817_562171_+	hypothetical protein	NA	NA	NA	NA
WP_001066299.1\|562375_563512_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	1.2e-23	31.0
WP_001808905.1\|563833_564028_-	hypothetical protein	NA	NA	NA	NA
WP_000777760.1\|564189_564477_-	hypothetical protein	NA	NA	NA	NA
WP_001278301.1\|564486_564897_-	HIT family protein	B5LJ12	Mycobacterium_phage	3.4e-05	31.6
WP_000889923.1\|564964_565696_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.0e-25	28.6
WP_000653752.1\|565692_566742_+	ABC transporter permease	NA	NA	NA	NA
WP_000132575.1\|566909_567239_-	hypothetical protein	NA	NA	NA	NA
WP_000682122.1\|567514_567853_+	response regulator transcription factor	NA	NA	NA	NA
WP_001219126.1\|567857_568595_+	response regulator transcription factor	NA	NA	NA	NA
WP_000275284.1\|568607_569948_+	sensor histidine kinase	NA	NA	NA	NA
WP_001814919.1\|570187_571534_-\|transposase	IS1380-like element ISSpn5 family transposase	A0A1X9I6F6	Streptococcus_phage	4.5e-78	40.0
WP_000358814.1\|571700_571856_-	quorum-sensing system pheromone BlpC	NA	NA	NA	NA
WP_001069099.1\|571912_573274_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_001093269.1\|574817_575066_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_000483697.1\|575081_575291_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_000497530.1\|576492_577068_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

807169 : 814175

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000405832.1\|807169_807664_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.9e-42	52.1
WP_001170347.1\|807663_808194_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.4e-46	54.3
WP_000889093.1\|808187_808544_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
WP_001103452.1\|808701_809502_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000590986.1\|809501_810245_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-29	41.0
WP_000926600.1\|810322_810547_+	DUF4059 family protein	NA	NA	NA	NA
WP_000272311.1\|810612_811524_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.9e-89	51.5
WP_000855734.1\|811561_812290_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_001272941.1\|812334_812946_-	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
WP_000930003.1\|813458_814175_+	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	2.1e-26	30.9

DBSCAN-SWA_7

927868 : 990928

Indivirus(15.79%)

transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000895725.1\|927868_928768_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_001814694.1\|928811_930338_-	ABC-F family ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	1.3e-09	31.9
WP_000773235.1\|931096_931639_+	DUF177 domain-containing protein	NA	NA	NA	NA
WP_000244451.1\|931638_932268_+	endonuclease III	NA	NA	NA	NA
WP_000850024.1\|932478_933000_+	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_001293845.1\|933018_933942_+	aspartate carbamoyltransferase catalytic subunit	M1HGA5	Paramecium_bursaria_Chlorella_virus	8.7e-25	31.7
WP_000166701.1\|933991_935071_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.3e-59	35.9
WP_001126406.1\|935383_938560_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_001199645.1\|938834_939644_-\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	4.5e-09	30.3
WP_000811992.1\|939645_940449_-\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	5.3e-10	27.1
WP_000835917.1\|940458_941946_-	type IV teichoic acid flippase TacF	NA	NA	NA	NA
WP_000638502.1\|942281_942989_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_000609885.1\|942993_944016_+	alcohol dehydrogenase catalytic domain-containing protein	NA	NA	NA	NA
WP_000411215.1\|944032_944902_+\|holin	choline kinase LicA	NA	NA	NA	NA
WP_000837618.1\|944891_945770_+	DMT family transporter	NA	NA	NA	NA
WP_000643970.1\|945781_946471_+	NTP transferase domain-containing protein	A0A127AW70	Bacillus_phage	3.4e-05	45.0
WP_000705301.1\|946566_947415_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	1.2e-33	39.1
WP_001812883.1\|948296_949340_+	TIGR00341 family protein	NA	NA	NA	NA
WP_000179644.1\|949506_951594_+	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	1.0e-105	37.6
WP_001237223.1\|951699_952059_+	YbaN family protein	NA	NA	NA	NA
WP_000638786.1\|952151_952784_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_000461600.1\|952827_953484_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_001010953.1\|953502_954135_+	2-isopropylmalate synthase	NA	NA	NA	NA
WP_000225489.1\|954162_954597_+	DNA topoisomerase I	NA	NA	NA	NA
WP_001074730.1\|954608_955646_+	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_000762426.1\|955642_955912_+	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_000929149.1\|955915_956275_+	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_001042415.1\|957225_959157_+	McrB family protein	K4I1H4	Acidithiobacillus_phage	1.8e-16	33.7
WP_001816429.1\|959143_960460_+	McrC family protein	NA	NA	NA	NA
WP_000931158.1\|960634_961621_+	GMP reductase	G3MBI2	Bacillus_virus	1.4e-137	72.2
WP_000661503.1\|961938_962637_+	ribonuclease III	J2YAN1	Acanthamoeba_polyphaga_lentillevirus	1.1e-24	33.3
WP_000280942.1\|962627_966167_+	chromosome segregation protein SMC	NA	NA	NA	NA
WP_000153016.1\|966163_966958_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000763457.1\|966957_967776_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000522312.1\|967779_969069_+	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
WP_000096139.1\|969112_970600_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	4.9e-70	33.0
WP_001096313.1\|970748_971489_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-32	40.1
WP_000726258.1\|971488_973654_-	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_000792112.1\|973823_974777_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000610410.1\|974853_976842_+	excinuclease ABC subunit B	NA	NA	NA	NA
WP_000639833.1\|976851_977415_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000237188.1\|977380_977869_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000091545.1\|977941_978409_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_000159178.1\|978405_978921_-	transcription repressor NadR	NA	NA	NA	NA
WP_001097402.1\|978932_979460_-	ECF transporter S component	NA	NA	NA	NA
WP_000747408.1\|979741_980305_-	ECF transporter S component	NA	NA	NA	NA
WP_001284130.1\|980288_980840_-	phosphopantothenoylcysteine decarboxylase	A0A068EHP1	Penguinpox_virus	5.2e-25	37.6
WP_000699489.1\|980851_981541_-	phosphopantothenate--cysteine ligase	NA	NA	NA	NA
WP_000845287.1\|981770_983441_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_000886147.1\|983769_984945_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000722076.1\|984999_985704_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.8e-39	39.8
WP_000886210.1\|985696_987046_+	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	1.8e-34	34.6
WP_001289493.1\|987047_987857_+	MBL fold metallo-hydrolase	A0A0C5AFC1	Paenibacillus_phage	1.8e-34	39.0
WP_000208080.1\|987947_988190_+	hypothetical protein	NA	NA	NA	NA
WP_001812387.1\|988191_988446_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_000731129.1\|988492_989266_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	8.9e-23	48.6
WP_001814919.1\|989581_990928_-\|transposase	IS1380-like element ISSpn5 family transposase	A0A1X9I6F6	Streptococcus_phage	4.5e-78	40.0

DBSCAN-SWA_8

1236886 : 1290674

Streptococcus_phage(44.44%)

integrase,tRNA,bacteriocin,holin,protease,transposase

attL 1241252:1241296|attR 1294336:1294380

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000083726.1\|1236886_1238221_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_001166874.1\|1238407_1239286_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.7
WP_000358228.1\|1239288_1239606_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
WP_000806706.1\|1239645_1240536_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.4e-72	51.4
WP_000033363.1\|1240532_1241171_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.2e-75	67.6
1241252:1241296	attL	NA	NA	NA	NA
WP_000689709.1\|1241390_1242188_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	2.7e-59	50.6
WP_000254686.1\|1242191_1243454_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.5e-139	64.5
WP_001844793.1\|1243463_1244594_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-114	58.4
WP_000728251.1\|1244673_1246557_-\|holin	phosphorylcholine esterase CbpE	Q332B9	Clostridium_botulinum_C_phage	7.3e-10	23.7
WP_000403195.1\|1246559_1247447_-	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.3e-09	28.0
WP_000745389.1\|1247436_1247898_-	signal peptidase II	NA	NA	NA	NA
WP_001025704.1\|1247894_1248803_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	3.1e-06	27.7
WP_001809535.1\|1248795_1248993_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000745372.1\|1249044_1249716_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000602451.1\|1249769_1249991_-\|bacteriocin	SP_0924 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000593571.1\|1250262_1251072_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_001246755.1\|1251252_1252128_-	N-carbamoylputrescine amidase	M1H5W0	Paramecium_bursaria_Chlorella_virus	1.1e-77	50.0
WP_000969458.1\|1252137_1253223_-	agmatine deiminase	M1HES8	Acanthocystis_turfacea_Chlorella_virus	2.8e-91	48.1
WP_000764377.1\|1253219_1254347_-	carboxynorspermidine decarboxylase	NA	NA	NA	NA
WP_000088782.1\|1254346_1255606_-	saccharopine dehydrogenase family protein	NA	NA	NA	NA
WP_000366713.1\|1255602_1256463_-	polyamine aminopropyltransferase	NA	NA	NA	NA
WP_001270407.1\|1256493_1256631_-	hypothetical protein	NA	NA	NA	NA
WP_000661006.1\|1257398_1258874_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001153814.1\|1259580_1260456_+\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	8.0e-28	31.3
WP_029645384.1\|1260451_1261030_+	VIT1/CCC1 transporter family protein	NA	NA	NA	NA
WP_000489404.1\|1261072_1263061_-	ABC transporter permease	NA	NA	NA	NA
WP_000173358.1\|1263062_1263821_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-27	36.3
WP_000680766.1\|1264248_1264440_+	hypothetical protein	NA	NA	NA	NA
WP_001085044.1\|1264793_1265066_-	PspC domain-containing protein	NA	NA	NA	NA
WP_000778595.1\|1265124_1265574_-	SprT family protein	NA	NA	NA	NA
WP_000359141.1\|1265560_1267690_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_000123624.1\|1268101_1269007_+	permease	NA	NA	NA	NA
WP_000617835.1\|1269003_1269819_+	TIGR03943 family protein	NA	NA	NA	NA
WP_000759775.1\|1269948_1270665_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000749599.1\|1271613_1272486_-	DUF4300 family protein	NA	NA	NA	NA
WP_001814919.1\|1273997_1275344_+\|transposase	IS1380-like element ISSpn5 family transposase	A0A1X9I6F6	Streptococcus_phage	4.5e-78	40.0
WP_001042807.1\|1275846_1277352_-	pyruvate kinase	NA	NA	NA	NA
WP_000820852.1\|1277410_1278418_-	6-phosphofructokinase	NA	NA	NA	NA
WP_000561516.1\|1278500_1281602_-	DNA polymerase III subunit alpha	A0A291AWR1	Streptomyces_phage	6.8e-114	32.8
WP_001212037.1\|1281948_1284222_+	Xaa-Pro dipeptidyl-peptidase	NA	NA	NA	NA
WP_001043000.1\|1284238_1284709_+	arginine repressor	NA	NA	NA	NA
WP_000692989.1\|1284825_1284981_-	hypothetical protein	NA	NA	NA	NA
WP_000526343.1\|1285251_1288602_-	DEAD/DEAH box helicase family protein	A0A2H4P9W3	Gordonia_phage	1.4e-11	24.8
WP_000756225.1\|1288631_1289675_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000444456.1\|1289708_1290674_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	1.8e-33	29.6
1294336:1294380	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1473655 : 1480409

Streptococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000081004.1\|1473655_1474624_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	1.8e-65	99.2
WP_000011306.1\|1474657_1475569_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.5e-154	99.7
WP_001231086.1\|1475565_1476543_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
WP_000163057.1\|1476539_1477430_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.9e-06	29.8
WP_001140420.1\|1477481_1477862_-	RidA family protein	NA	NA	NA	NA
WP_000422605.1\|1477872_1478460_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_000106341.1\|1478468_1479701_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	8.4e-132	59.2
WP_000442276.1\|1479732_1479903_-	hypothetical protein	NA	NA	NA	NA
WP_000162444.1\|1479902_1480409_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	3.9e-27	42.5

DBSCAN-SWA_10

1734911 : 1742242

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001814725.1\|1734911_1735631_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	4.7e-34	36.2
WP_000778475.1\|1736034_1736994_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	2.4e-57	40.8
WP_001193665.1\|1736983_1737940_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_000764303.1\|1737936_1738689_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.6e-14	28.1
WP_000858251.1\|1738784_1739750_+	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000821615.1\|1739974_1740217_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.8e-18	59.4
WP_001222228.1\|1740216_1740939_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000105310.1\|1740925_1741495_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
WP_000351913.1\|1741513_1742242_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.1e-09	22.3

DBSCAN-SWA_11

1823684 : 1850256

Streptococcus_phage(92.0%)

integrase,bacteriocin

attL 1815384:1815399|attR 1852800:1852815

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1815384:1815399	attL	NA	NA	NA	NA
WP_000420682.1\|1823684_1823999_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000985015.1\|1824014_1824401_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000813488.1\|1824429_1825815_+	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000879507.1\|1825817_1825970_+	hypothetical protein	NA	NA	NA	NA
WP_000398284.1\|1825992_1827198_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_001009056.1\|1827240_1827462_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000342539.1\|1827578_1828076_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_000506270.1\|1828050_1828557_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000331160.1\|1828540_1830988_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_001814875.1\|1830990_1833168_+	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	98.6
WP_000769868.1\|1833164_1834166_+	bifunctional lysozyme/C40 family peptidase	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_001224318.1\|1834162_1835095_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
WP_001814923.1\|1835339_1835456_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691729.1\|1835471_1837391_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.3
WP_001813542.1\|1837754_1838000_+	hypothetical protein	A0A1B0RXA7	Streptococcus_phage	2.6e-37	98.8
WP_000806926.1\|1837996_1838332_+	hypothetical protein	NA	NA	NA	NA
WP_000567222.1\|1838344_1838713_+	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.1e-58	97.5
WP_001072467.1\|1838699_1838999_+	hypothetical protein	A0A1B0RX98	Streptococcus_phage	1.8e-48	96.0
WP_000420313.1\|1839116_1840580_-	ABC-F type ribosomal protection protein Msr(D)	A0A1B0RXA0	Streptococcus_phage	3.7e-251	97.3
WP_000417519.1\|1840699_1841917_-	macrolide efflux MFS transporter Mef(A)	A0A2K5B2B5	Erysipelothrix_phage	5.1e-198	90.6
WP_000873143.1\|1842302_1842473_-	hypothetical protein	A0A1X9I6E4	Streptococcus_phage	3.7e-22	98.2
WP_001860868.1\|1842994_1843186_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	5.4e-14	69.4
WP_001227347.1\|1843245_1843599_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000804885.1\|1844103_1844526_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_000857133.1\|1844522_1844753_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000814511.1\|1845213_1845417_+	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_001291561.1\|1845498_1846716_+\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000732395.1\|1847606_1849622_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000571425.1\|1849623_1850256_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.8e-22	32.9
1852800:1852815	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2129194 : 2137948

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000510412.1\|2129194_2130034_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	1.1e-15	32.6
WP_000835715.1\|2130018_2130846_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	2.8e-22	32.9
WP_000712136.1\|2130842_2131388_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_001227958.1\|2131398_2132220_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000170193.1\|2132261_2133545_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	7.1e-17	29.5
WP_000424257.1\|2133541_2134792_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	6.0e-93	42.1
WP_000455903.1\|2134950_2135319_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	7.0e-18	57.3
WP_000266662.1\|2135321_2136419_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_000073428.1\|2136469_2137948_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.2e-94	40.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017769

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection