CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016801	Corynebacterium diphtheriae C7 (beta), complete sequence	1 crisprs	cas1,cas2,DEDDh,csa3,cas3,WYL,cas4,DinG	2	5	4	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_016801_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016801_1

40845-41327

orTypeII

Consensus_repeat	Method
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CRISPRCasFinder
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CRT
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	PILER-CR

7 spacers

cas2,cas1,cas9

The CRISPR arrays of NC_016801_1

>merge|NC_016801|1|40845-41327|CRISPRCasFinder,CRT,PILER-CR
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGCATGATACGCGGGCTGATGCGCGGCATGCGAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGCCTGCCTGGTATAGGTCAGCGGCGAATCGGAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGCTTATTAGCTCATGGAACGCATCGAACTCGAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGCCCCCGCACCGTGGGGCGCTGGGGAGGTCGAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGCGGTGGCGTTAACTGGGGTGACTGCTCCGGAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGCTGCGCTATATCAGCCCACCACGGCTGAGGAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGCCCGCACCAGCGGGGATGAACCGTAGGAGAAGTTTATCAGGGTTTTTGGGAATGAGGGTGCCTG

>NC_016801|1|1|40845-41264|CRISPRCasFinder
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	ATGATACGCGGGCTGATGCGCGGCATGC
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CTGCCTGGTATAGGTCAGCGGCGAATCG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	TTATTAGCTCATGGAACGCATCGAACTC
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CCCCGCACCGTGGGGCGCTGGGGAGGTC
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	GGTGGCGTTAACTGGGGTGACTGCTCCG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	TGCGCTATATCAGCCCACCACGGCTGAG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC

>NC_016801|1|1|40845-41327|CRT
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	ATGATACGCGGGCTGATGCGCGGCATGC
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CTGCCTGGTATAGGTCAGCGGCGAATCG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	TTATTAGCTCATGGAACGCATCGAACTC
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CCCCGCACCGTGGGGCGCTGGGGAGGTC
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	GGTGGCGTTAACTGGGGTGACTGCTCCG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	TGCGCTATATCAGCCCACCACGGCTGAG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CCGCACCAGCGGGGATGAACCGTAGGA
GAAGTTTATCAGGGTTTTTGGGAATGAGGGTGCCTG

>NC_016801|1|1|41037-41264|PILER-CR
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	CCCCGCACCGTGGGGCGCTGGGGAGGTC
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	GGTGGCGTTAACTGGGGTGACTGCTCCG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC	TGCGCTATATCAGCCCACCACGGCTGAG
GAAGTCTATCAGGGTTTTTGAGAACTGAACCCCAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016801.1\|WP_014307737.1\|51420_51909_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|224630
NC_016801.1\|WP_014301108.1\|48616_49966_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	unknown	unknown	gnl\|CDD\|223843
NC_016801.1\|WP_014318428.1\|32545_33331_+\|thiazole-synthase	unknown	unknown	gnl\|CDD\|234687
NC_016801.1\|WP_014318435.1\|47159_48620_-\|penicillin-binding-protein-2	unknown	unknown	gnl\|CDD\|223839
NC_016801.1\|WP_014302655.1\|30606_31275_+\|thiamine-phosphate-synthase	unknown	unknown	gnl\|CDD\|234590
NC_016801.1\|WP_014318434.1\|45620_47147_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016801.1\|WP_014302657.1\|32343_32544_+\|sulfur-carrier-protein-ThiS	unknown	unknown	gnl\|CDD\|273754
NC_016801.1\|WP_014318438.1\|54004_54520_-\|hypothetical-protein	unknown	unknown	unknown
NC_016801.1\|WP_014318433.1\|43614_45624_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016801.1\|WP_021334744.1\|51922_52789_-\|DUF3662-and-FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|378850
NC_016801.1\|WP_014302656.1\|31271_32360_+\|glycine-oxidase-ThiO	unknown	unknown	gnl\|CDD\|274092
NC_016801.1\|WP_014318429.1\|34337_35192_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|237797
NC_016801.1\|WP_014318427.1\|28823_30623_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_016801.1\|WP_014318431.1\|36308_39563_+\|HNH-endonuclease	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|375896
NC_016801.1\|WP_003849883.1\|43228_43498_-\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907
NC_016801.1\|WP_014318436.1\|49966_51421_-\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NC_016801.1\|WP_014301100.1\|39566_40481_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NC_016801.1\|WP_003853358.1\|40464_40794_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_016801.1\|WP_014302659.1\|33330_34341_+\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|235528
NC_016801.1\|WP_013910511.1\|53298_53598_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_016801.1\|WP_014307737.1\|51420_51909_-\|FHA-domain-containing-protein	gnl\|CDD\|224630	COG1716, COG1716, FOG: FHA domain [Signal transduction mechanisms].	4.98161e-18
NC_016801.1\|WP_014301108.1\|48616_49966_-\|FtsW/RodA/SpoVE-family-cell-cycle-protein	gnl\|CDD\|223843	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning].	2.78845e-82
NC_016801.1\|WP_014318428.1\|32545_33331_+\|thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	8.17818e-147
NC_016801.1\|WP_014318435.1\|47159_48620_-\|penicillin-binding-protein-2	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	8.23208e-81
NC_016801.1\|WP_014302655.1\|30606_31275_+\|thiamine-phosphate-synthase	gnl\|CDD\|234590	PRK00043, thiE, thiamine phosphate synthase.	4.93107e-63
NC_016801.1\|WP_014318434.1\|45620_47147_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.78255e-107
NC_016801.1\|WP_014302657.1\|32343_32544_+\|sulfur-carrier-protein-ThiS	gnl\|CDD\|273754	TIGR01683, thiamine_biosynthesis_protein_ThiS, thiamine biosynthesis protein ThiS. This model represents ThiS, a small, ubiquitin-like thiamine biosynthesis protein related to MoaD, a molybdenum cofactor biosynthesis protein. Both proteins are involved in sulfur transfer. ThiS has a conserved Gly-Gly C-terminus that is modified, in reactions requiring ThiI, ThiF, IscS, and a sulfur atom from Cys, into the thiocarboxylate that provides the sulfur for thiazole biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	8.21875e-20
NC_016801.1\|WP_014318433.1\|43614_45624_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.17363e-122
NC_016801.1\|WP_021334744.1\|51922_52789_-\|DUF3662-and-FHA-domain-containing-protein	gnl\|CDD\|378850	pfam12401, DUF3662, Protein of unknown function (DUF2662). This domain family is found in bacteria, and is approximately 120 amino acids in length. The family is found in association with pfam00498.	6.35939e-42
NC_016801.1\|WP_014302656.1\|31271_32360_+\|glycine-oxidase-ThiO	gnl\|CDD\|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	5.08136e-128
NC_016801.1\|WP_014318429.1\|34337_35192_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|237797	PRK14713, PRK14713, bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.	7.39405e-110
NC_016801.1\|WP_014318427.1\|28823_30623_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_016801.1\|WP_014318431.1\|36308_39563_+\|HNH-endonuclease	gnl\|CDD\|375896	pfam18470, Cas9_a, Cas9 alpha-helical lobe domain. This is an alpha-helical lobe domain found in Cas9 proteins. Cas9 enzymes adopt a bilobed architecture composed of a nuclease lobe containing juxtaposed RuvC and HNH nuclease domains and a variable alpha-helical lobe likely to be involved in nucleic acid binding. Amino acid residues located in both the nuclease and alpha-helical lobe clefts are highly conserved within type II-A Cas9 proteins.	2.60774e-122
NC_016801.1\|WP_003849883.1\|43228_43498_-\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	2.52021e-46
NC_016801.1\|WP_014318436.1\|49966_51421_-\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.76599e-73
NC_016801.1\|WP_014301100.1\|39566_40481_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	9.16407e-115
NC_016801.1\|WP_003853358.1\|40464_40794_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.12332e-19
NC_016801.1\|WP_014302659.1\|33330_34341_+\|ThiF-family-adenylyltransferase	gnl\|CDD\|235528	PRK05600, PRK05600, thiamine biosynthesis protein ThiF; Validated.	0

>NC_016801.1|WP_003853358.1|40464_40794_+|CRISPR-associated-endonuclease-Cas2
MPKKGSDPVWCVVMFDLPVKTKTQRKQATAFRQNLLDLGFCMAQLSVYVQYLPLAAKLSNLVKLIKEKLPPGGDVRILSVSDIQWSKMIRFSSSAEVSGEEKPDQLAIF
>NC_016801.1|WP_014301100.1|39566_40481_+|type-II-CRISPR-associated-endonuclease-Cas1
MNPGWRVVDLIDFDGKVSYQRGQLAITSDSGELRATLPLAQIAVVLIGNKIIISGAVLVKLSEYDIAVLVCDWRRVPVAGSFSWNEHTRIAARQRAQASLSLPRQKSAWAQIIKAKILGQARTAAQLGFDATDLKNLARAVRSGDVDNREAMAAKRYWEIISTEDDFRRLPGLAATGWNGALDYAYTVLRGHGMRAICSAGLVGTLGVFHHGRGNQFALVDDLIEPFRPAIDYAVFSIVSNAQELDKETKRQLVAAVEEPFNSAGQSIPTVFTAFAQQYGRYVEGDVEKLVPPIWEGPFDAEER
>NC_016801.1|WP_014318431.1|36308_39563_+|HNH-endonuclease
MKYHVGIDVGTFSVGLAAIEVDDAGMPIKTLSLVSHIHDSGLDPDKIKSAVTRLASSGIARRTRRLYRRKRRRLQQLDKFIQRQGWPVIELEDYSDPLYPWKVRAELAASYIADEKERGEKLSVALRHIARHRGWRNPYAKVSSLYLPDEPSDAFKAIREEIKRASGQPVPETATVGQMVTLCELGTLKLRGEGGVLSARLQQSDHAREIQEICRMQEIGQELYRKIIDVVFAAESPKGSASSRVGKDPLQPGKNRALKASDAFQRYRIAALIGNLRVRVDGEKRILSVEEKNLVFDHLVNLAPKKEPEWVTIAEILGIDRGQLIGTATMTDDGERAGARPPTHDTNRSIVNSRIAPLVDWWKTASALEQHAMVKALSNAEVDDFDSPEGAKVQAFFADLDDDVHAKLDSLHLPVGRAAYSEDTLVRLTRRMLADGVDLYTARLQEFGIEPSWTPPAPRIGEPVGNPAVDRVLKTVSRWLESATKTWGAPERVIIEHVREGFVTEKRAREMDGDMRRRAARNAKLFQEMQEKLNVQGKPSRADLWRYQSVQRQNCQCAYCGSPITFSNSEMDHIVPRAGQGSTNTRENLVAVCHRCNQSKGNTPFAIWAKNTSIEGVSVKEAVERTRHWVTDTGMRSTDFKKFTKAVVERFQRATMDEEIDARSMESVAWMANELRSRVAQHFASHGTTVRVYRGSLTAEARRASGISGKLEFLDGVGKSRLDRRHHAIDAAVIAFTSDYVAETLAVRSNLKQSQAHRQEAPQWREFTGKDAEHRAAWRVWCQKMEKLSALLTEDLRDDRVVVMSNVRLRLGNGSAHEETIGKLSKVKLGSQLSVSDIDKASSEALWCALTREPDFDPKDGLPANPERHIRVNGTHVYAGDNIGLFPVSAGSIALRGGYAELGSSFHHARVYKITSGKKPAFAMLRVYTIDLLPYRNQDLFSVELKPQTMSMRQAEKKLRDALATGNAEYLGWLVVDDELVVDTSKIATDQVKAVEAELGTIRRWRVDGFFGDTRLRLRPLQMSKEGIKKESAPELSKIIDRPGWLPAVNKLFSEGNVTVVRRDSLGRVRLESTAHLPVTWKVQ
>NC_016801.1|WP_014318429.1|34337_35192_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MTPHILTIAGSDPSGGAGIQADLKSIMAAGGYGMAAITALTAQNTCGVTAIHTPPTEFLSEQLRAISDDITIHAIKIGMIGSSDAATATATWLDQLPHTPIVVLDPVMVATSGSVLGQRHYFEPLLHHATVITPNLPELAVLTNNHDPEQAEHAARSLAEQYDCAVLLKGGHRHGTDDLGNTWITASGPQFHAPSPRIHTTNTHGTGCSLSSALATRLAIEPPEPALHWATTWLNGAIAHGSDLNVGHGNGPVDHSYRLEEYSANCNTHPKNSRRATFNMAPQL
>NC_016801.1|WP_014302659.1|33330_34341_+|ThiF-family-adenylyltransferase
MLDELERQRVARQLRLPGFGIEQQERLNKGRVLVIGAGGLGSPALQSLVAAGVGSIRLVDNDTVDVSNIQRQILFGVGDVGRSKVHVAAERLRAIQPGIRIDAHTERLTAHNAHELAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHMGVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGSITTYNALTSTFRTYTVGRDPLRPAARTLHTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWDDTTAIQHALDNITTDNVVVVCASGIRSAAFIEQFAHLNPHLTFHNVPSGINELP
>NC_016801.1|WP_014318428.1|32545_33331_+|thiazole-synthase
MLTIAHRSFQSHLIMGTGGASSFDTLEKSLIASGTELTTVAMRRHAAHTGAHGESVFELMQRLNITPLPNTAGCRTARDAILTAQLAREALDTSWIKVEVIADDTTLLPDVLELIDATETLTNDGFTVLAYTSDDPVVAQRLEDAGAAAVMPLGSPIGTGLGILNPHNIELICSRATVPVLLDAGIGTASDATLAMELGCAGVLLASAINRCINPITMATAMKHAVEAGRLAREAGRIPRREHAVASSSFEGLASWADEVL
>NC_016801.1|WP_014302657.1|32343_32544_+|sulfur-carrier-protein-ThiS
MDIYINDTLTTIESPQLTEIISNHCNGIRPGIAVAINQRVIPRSQWDTTTVTAGDHLDILTAVQGG
>NC_016801.1|WP_014302656.1|31271_32360_+|glycine-oxidase-ThiO
MKIAVVGGGIVGLSTAFELSTRGYNVHVFDPNPASGASHFAGGMLAPAAEVQFQQDPLFPLMKRAGKLWPDMVRWVAQHTNLPTGYRTEGTLVVAADRADAEHLKQLRATQEAAGMDVRPITTRQARGLEPALGPRLSAAVHIPNDTQVAPRVFLTALLDALDDCGVEVTKEKITDLEPLYQQFDVVVLAAGLGAQHLSPIPLALRPVRGDILRVQTEPGAVNMVVRGWVNDRPIYIIPRANGEIAIGATSREDERDLPSVEGIYDLLRDAIRVVPGIVDSSLIEANVGVRPGTPDDLPYLGWASDRLIISTGYFRHGILLSSLGAHVTACLIDGTDPGIDLTACAPDRHHNERGTTHGHLH
>NC_016801.1|WP_014302655.1|30606_31275_+|thiamine-phosphate-synthase
MLPTPRWGRDFDPRCYFVTGTGSVDHIVDVARQAARAGAGLIQVRSKPIAARDLYILGREVARAVTEVNPRTRVLIDDRVDVALALMNNGEHIHGVHVGQDDLPVRHVRALLGDNAIIGLTTGTLELVRASRQVAEVIDYIGAGPFRPTPTKDSGRAPVGLAGYPPLVAESLVPVVAIGDVRPEDAADLAATGVAGVAIVRALMNSQDVATDVKLVLKGFAQ
>NC_016801.1|WP_014318427.1|28823_30623_+|phosphomethylpyrimidine-synthase-ThiC
MSAASANSATNPSAWENSEIHPKHSYSPIVSGDLEVPETEIQLDDSPTGSNDPVRIYRTRGPECDPTVGLKPLRAQWIDNREDTEEYAGRERNLADDGRSAQRRGAASLEWKGVKPAPRRAKQGKRVTQMHYARQGIITKEMEFVALREHMDPEFVRSEIARGRAIIPNNINHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLRWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTKRVTGIVSRGGSIMAGWCLAHHKESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSVADANDAAQFAELKTIGELARRAWEYDVQVMIEGPGHVPLNMVQENNELEQKWAHDAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWHDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFADKITDLGIPQVGGDAEAGMAAKSEEFVAQGSQLYSEVRDNAAHA
>NC_016801.1|WP_003849883.1|43228_43498_-|cell-division-protein-CrgA
MPKSKINHSSTAYTAGSTANRTPVKINSTGTPLWYKIIMFGLILAGLLWLIVNYLAGQDISFMTELGPWNYGIGFGLFIIGLLMTMGWR
>NC_016801.1|WP_014318433.1|43614_45624_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTDIVLADRYRLGDVIGTGGMSEVYEATDVLLGRKVAVKMLRADLARDVNFRERFRREAQNSGKLNHPAIVAVYDTGETPRAGLNTPYIVMELVNGRTLRDIVREDGPLTPSQAAHTLIPVCHALQVSHDAGIIHRDIKPANVMITNTGAVKIMDFGIARALDDATSAMTQTSAVIGTAQYLSPEQARGKLADARSDVYALGCVLYETLTGKPPFEGETPFAVAYQHVQEDPVKPSEYIADLSPTAAINVDAVVLTAMSKHPGDRYQTAQEMCADLERLERNAVTDAARHYVTPTSFATQDPASTTVVPVTQVTELDHAEAGAGVVPAGAVAGSAAVAGSGGAHAAPRSSNRGLRILAAILAVLVLAVGAGFAIDYFGGGPFSQRSTVTIPKLQNSTQQDAVSQLEKLGLQVNVIEEPNPDIPRGKVIRTNPTDGSNVQRNSTVRLTISSGKEITEVPDLSGKNTADAVKILEAAGLLLDPTVREDSSDTVPKGEIIEVSPAAGSQVSRGSKVSITVSTGVETVRVPVITGMKWDQAEGNLTSLGFKPEVVRVDSVEPAGTVVAVPDEGAEVPKGSSVTVQISNGAMFTVPEITRQTIGDAVRILHDAGWNGNASRLIQAAKVPTVAVTDQNLIASQLPTPGTALRKDAPIEIRLYEFNLAALVPPAQH
>NC_016801.1|WP_014318434.1|45620_47147_-|serine/threonine-protein-kinase
MTQSQSPDPALQALVGSDYALQWVVGNGGMSTVWLADDLRNQREVAIKVLRPEFSDNEEFLSRFRNEALASEHIDSDNVVRTYDYREVTDDMGRTLCFIVMEYVRGESLADMLARKGRLEEDLALDVLEQAAHGLSIIHRMGMVHRDIKPGNLLITQNGQVKITDFGIAKAAAAVPLTRTGMVVGTAQYVSPEQAQGRDVTAATDVYSLGVVGYEMLVGQRPFTGDSSVSVAIAHINQAPPAMPTSVSAPARELIGIALRKDPAHRYADGNELALAVSATRMGQRPPQPKSAPLQHIAPQPAPTESTYALGATAQPTTVIPATGQVLAAPTAAPAAAAYPASTVIPAGTPRQEPEKQSSGWGAGIVVGALAALLLGTAAWAASQGMFDDLFDKTPQSSESSVPPPPVTATVTETPTPQITTVVPEPLPTSSPEPTLSETKRTPDESHPSSDHQLPSVRPSHNGRPSSQAPHAPQAPTQDADQPAESPAPDTLDSLIENLNKLNQGGAQ
>NC_016801.1|WP_014318435.1|47159_48620_-|penicillin-binding-protein-2
MNRSIRFTSVFALLLILILLVNLTIIQGFSQEKYAHNALNRRGFIELKSQARGQISTGGQVLAESYQDEEGFYQRRYVTNPAIYGPIEGYLSDIYGASGMESNLNGVLSGTDSSVSVRRWTDELLGRKHSGVNVELTLLPQVQEVAYNQMANAGYEGAVVAIKPSTGEILAMASTPSYDPSAIVNPDTAEQTWAALNANPGNPLLNHATQETLPPGSTFKVITTAAGLNAGYGPGSMLTGQDRITLPDGITTLENYAGQTCAGSQNVTLATAFQYSCNTAFVQMGIDVGQEKFDEAAHAFGVNDRYDLGVDMAPGTIGDVSDPSARGQSSIGQRDVAMSVLHNAVVAATVANGGKRMEPHLVSRIVGQDLKVIKETKPHQINEAVTPEVAATLTDLMRLSERHTAGYTGADIASKTGTAEHGEDSRNSNPHAWYIAFGPSANADVAVAVVVKNGGDAGQAATGGSVAAPIGRAVIAAAQAALAARG
>NC_016801.1|WP_014301108.1|48616_49966_-|FtsW/RodA/SpoVE-family-cell-cycle-protein
MTFLRRITARPVEFGLLVMATLLIAVTLINLNMAQGLSVTSETLWVIGGFIGVFTIAHLALCFTAPHADQVMLPVASVLNGLGLVMVYRIDLARDTALASRQVIWTLVGILLMIAVLVFIRDHRMLSRYSYVLGLLGLILLALPMVWPTKMNADANIWISIGPFSVQPGEFSKILLLIFFAQLLVNKRALFNVAGYRFLGLEFPRLRDLGPILGVWAFAILVMAGENDFGPALLLFSTVLGMLYLATNRVSWLIIGAALVAVGGTALYQISSKIQSRVTNFINPLDNFNGTGYQLSQSLFGLSSGGVAGAGLGLGHPELIPVAESDFILAAVGEELGFIGLAAVLVLFAIFITRGLRTALRARDSYGKLMAAGLSLTLAIQVFVVTAGITALMPMTGLTTPFMSQGGSSLMANYILLGLILRISHSTQAAANDVVSMDEQAARGQEAHR
>NC_016801.1|WP_014318436.1|49966_51421_-|serine/threonine-protein-phosphatase
MLRLNYAAASDRGLVRGNNEDSAYAGPHLIALADGMGGHAAGEVASQLMINHLMRLDADVDDNDMLALLASVADDANRAIAQGVRDVPETDGMGTTLTALMFNGADLAMCHVGDSRGYRLRDGALEQITVDDTYVQSLVDKGQLAPEDVSTHPQRSMILKAYTGRPVEPTLKMIDIRPGDRFLLCSDGLSDPVTHSTIETTLQQGTPQEAARRLVDLALRSGGPDNVTVVVADVVEADGSDKSAAAASLPVTPLTVGALNSGMPEDPRPDTAAGRAAMAIAQRQPQVILPDPEPVKEATPSPRHRMVGVISALVVLAVLISAGWWGSSMVKNNYYVTTADSDSAQGTLVIENGIDVSLLGKSLHSTYQFACLSPEGDLTFVDSADAEKSCHRFRLSDLKESARGQVSTLPDGSYDEVQQQLQRLAEQTLPACITRQAAQPKDKDKKKPAAPSSAAATTTKAASPSSTGSPDDLSTPGETCREVK
>NC_016801.1|WP_014307737.1|51420_51909_-|FHA-domain-containing-protein
MESVIVFLLRIALLVLLWLLILLALYIQRKDAKSAAQTTVAPQAVTGLGVSSASSPLKKVSRRGGAPQQIVVVEGPLTGSSMQLDSLTEITLGRSKDCDFVVGDDYASARHARLIKRGSEWFAEDLDSRNGTYVGGYRIDQPEKVSAGSDIKIGRTTVRLVA
>NC_016801.1|WP_021334744.1|51922_52789_-|DUF3662-and-FHA-domain-containing-protein
MSIMGKVAKLDSAMQRGLDNSFAFVFGGKLVPAEIEELLKQEVQDNIVRAYEGGVESPNVFRVRVSRKDAQNLAQRYPSLADDFADRLSRYTRNQGWSTEGPVVVTIAADSGLRTGQLHASSAFDPAPQEYSHFIGVEDDVVTAAPTNDESNYESESGMNSYDADPRTEYMTAQAPDAIYTEVPVPEPKATPTVSLLLQDGSSRTYLVEEGSNIIGRSNEAHFRLPDTGVSRQHAEITWNGRDAILTDLKSTNGTTVNDTPVENWLLEDGDVITVGHSHIEVRIVEPN
>NC_016801.1|WP_013910511.1|53298_53598_-|hypothetical-protein
MKEKKLSSLVFGNVILESQILGTTIRIYADDMRSYSFRPSPYASLSVPLNELKGQLQPDHAEALAKKVFDSVAEELNKNYPGGCERAEKELKAWLMRTN
>NC_016801.1|WP_014318438.1|54004_54520_-|hypothetical-protein
MTSQIKERFYDFAISNGNPHSRWRNPRSTRLLITGYFTSLTLALIFELLMFAWIHFIWIFIACMFIAMTCWTVLRSTIDLKDMAPEDRLDDYEKAVINQWRQRSLSTALSLLFIGGLAAIIASASFIATDSPLSPNLLAIFAGLYMIYTYIFASSLPAVGYALTFNRNPEE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_016801_1	1.3\|41009\|28\|NC_016801\|CRISPRCasFinder,CRT	41009-41036	28	NC_016801.1	139939-139966	0	1.0
NC_016801_1	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	NC_016801.1	1112560-1112587	0	1.0

1. spacer 1.3|41009|28|NC_016801|CRISPRCasFinder,CRT matches to position: 139939-139966, mismatch: 0, identity: 1.0

ttattagctcatggaacgcatcgaactc	CRISPR spacer
ttattagctcatggaacgcatcgaactc	Protospacer
****************************

2. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to position: 1112560-1112587, mismatch: 0, identity: 1.0

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggtggcgttaactggggtgactgctccg	Protospacer
****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_016801_1	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	MN175604	Gordonia phage PhorbesPhlower, complete genome	12359-12386	2	0.929
NC_016801_1	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	MN892485	Gordonia phage Kuwabara, complete genome	13169-13196	2	0.929
NC_016801_1	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	MF140416	Mycobacterium phage LastHope, complete genome	13949-13976	3	0.893
NC_016801_1	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	MK460246	Mycobacterium phage Nibb, complete genome	13882-13909	3	0.893
NC_016801_1	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	KX557278	Gordonia phage Ghobes, complete genome	12139-12166	3	0.893
NC_016801_1	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	NC_048018	Gordonia phage Apricot, complete genome	13175-13202	3	0.893
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017130	Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence	124188-124214	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017130	Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence	124066-124092	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017134	Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence	124212-124238	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017134	Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence	124090-124116	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017101	Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence	124196-124222	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017101	Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence	124074-124100	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NZ_CP021924	Acetobacter pasteurianus subsp. pasteurianus strain SRCM101468 plasmid pAP1468-2	170385-170411	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NZ_CP021924	Acetobacter pasteurianus subsp. pasteurianus strain SRCM101468 plasmid pAP1468-2	171117-171143	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_013210	Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence	124568-124594	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_013210	Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence	124446-124472	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017136	Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence	124180-124206	4	0.852
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017136	Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence	124058-124084	4	0.852
NC_016801_1	1.1\|40881\|28\|NC_016801\|CRISPRCasFinder,CRT	40881-40908	28	NZ_LR594664	Variovorax sp. RA8 plasmid 3	144912-144939	5	0.821
NC_016801_1	1.3\|41009\|28\|NC_016801\|CRISPRCasFinder,CRT	41009-41036	28	AP018399	Xanthomonas phage XacN1 DNA, complete genome	19622-19649	5	0.821
NC_016801_1	1.3\|41009\|28\|NC_016801\|CRISPRCasFinder,CRT	41009-41036	28	AP018399	Xanthomonas phage XacN1 DNA, complete genome	338417-338444	5	0.821
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017130	Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence	123517-123543	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017134	Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence	123541-123567	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NZ_CP009803	Streptomyces sp. FR-008 plasmid pSSFR1, complete sequence	80081-80107	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017101	Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence	123525-123551	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NZ_CP020471	Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence	88022-88048	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246793-246819	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NZ_CP021924	Acetobacter pasteurianus subsp. pasteurianus strain SRCM101468 plasmid pAP1468-2	170263-170289	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_013210	Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence	123897-123923	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017136	Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence	123509-123535	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	MK977714	Corynebacterium phage Bran, complete genome	22540-22566	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_048780	Corynebacterium phage StAB, complete genome	22546-22572	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	MK977706	Corynebacterium phage Dina, complete genome	22371-22397	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	MH926061	Corynebacterium phage Troy, complete genome	22111-22137	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_048789	Corynebacterium phage Stiles, complete genome	22038-22064	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_048069	Corynebacterium phage SamW, complete genome	22111-22137	5	0.815
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_048790	Corynebacterium phage Lederberg, complete genome	22496-22522	5	0.815
NC_016801_1	1.4\|41073\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41073-41100	28	NZ_CP026518	Deinococcus sp. NW-56 plasmid unnamed2, complete sequence	282833-282860	6	0.786
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017130	Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence	123395-123421	6	0.778
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017134	Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence	123419-123445	6	0.778
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017101	Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence	123403-123429	6	0.778
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246732-246758	6	0.778
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_013210	Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence	123775-123801	6	0.778
NC_016801_1	1.7\|41265\|27\|NC_016801\|CRT	41265-41291	27	NC_017136	Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence	123387-123413	6	0.778
NC_016801_1	1.1\|40881\|28\|NC_016801\|CRISPRCasFinder,CRT	40881-40908	28	NZ_CP036351	Planctomycetes bacterium K2D plasmid pK2D_1, complete sequence	60605-60632	7	0.75
NC_016801_1	1.4\|41073\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41073-41100	28	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1736840-1736867	7	0.75

1. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to MN175604 (Gordonia phage PhorbesPhlower, complete genome) position: , mismatch: 2, identity: 0.929

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggtggcgtgaactggggtgactgctcgg	Protospacer
******** ***************** *

2. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to MN892485 (Gordonia phage Kuwabara, complete genome) position: , mismatch: 2, identity: 0.929

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggtggcgtgaactggggcgactgctccg	Protospacer
******** ********.**********

3. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to MF140416 (Mycobacterium phage LastHope, complete genome) position: , mismatch: 3, identity: 0.893

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggcggcgtcaactggggtgactgctcgg	Protospacer
**.*****.***************** *

4. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to MK460246 (Mycobacterium phage Nibb, complete genome) position: , mismatch: 3, identity: 0.893

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggtggcgtcaactggggcgactgctcgg	Protospacer
********.********.******** *

5. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to KX557278 (Gordonia phage Ghobes, complete genome) position: , mismatch: 3, identity: 0.893

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggtggcgtgcactggggtgactgctcgg	Protospacer
********  **************** *

6. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to NC_048018 (Gordonia phage Apricot, complete genome) position: , mismatch: 3, identity: 0.893

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggtggcgtgaactggggcgactgctctg	Protospacer
******** ********.********.*

7. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017130 (Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtaaca	Protospacer
******  ****************. *

8. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017130 (Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgca	Protospacer
******  *************** * *

9. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017134 (Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtaaca	Protospacer
******  ****************. *

10. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017134 (Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgca	Protospacer
******  *************** * *

11. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017101 (Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtaaca	Protospacer
******  ****************. *

12. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017101 (Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgca	Protospacer
******  *************** * *

13. spacer 1.7|41265|27|NC_016801|CRT matches to NZ_CP021924 (Acetobacter pasteurianus subsp. pasteurianus strain SRCM101468 plasmid pAP1468-2) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtaaca	Protospacer
******  ****************. *

14. spacer 1.7|41265|27|NC_016801|CRT matches to NZ_CP021924 (Acetobacter pasteurianus subsp. pasteurianus strain SRCM101468 plasmid pAP1468-2) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtaaca	Protospacer
******  ****************. *

15. spacer 1.7|41265|27|NC_016801|CRT matches to NC_013210 (Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtaaca	Protospacer
******  ****************. *

16. spacer 1.7|41265|27|NC_016801|CRT matches to NC_013210 (Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgca	Protospacer
******  *************** * *

17. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017136 (Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtaaca	Protospacer
******  ****************. *

18. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017136 (Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence) position: , mismatch: 4, identity: 0.852

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgca	Protospacer
******  *************** * *

19. spacer 1.1|40881|28|NC_016801|CRISPRCasFinder,CRT matches to NZ_LR594664 (Variovorax sp. RA8 plasmid 3) position: , mismatch: 5, identity: 0.821

atgatacgcgggctgatgcgcggcatgc	CRISPR spacer
atgacacgccggctgatgcgcggcggcc	Protospacer
****.**** **************.  *

20. spacer 1.3|41009|28|NC_016801|CRISPRCasFinder,CRT matches to AP018399 (Xanthomonas phage XacN1 DNA, complete genome) position: , mismatch: 5, identity: 0.821

ttattagctcatggaacgcatcgaactc	CRISPR spacer
aatttagcacatggaaagcatcgaactc	Protospacer
   ***** ******* ***********

21. spacer 1.3|41009|28|NC_016801|CRISPRCasFinder,CRT matches to AP018399 (Xanthomonas phage XacN1 DNA, complete genome) position: , mismatch: 5, identity: 0.821

ttattagctcatggaacgcatcgaactc	CRISPR spacer
aatttagcacatggaaagcatcgaactc	Protospacer
   ***** ******* ***********

22. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017130 (Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgcc	Protospacer
******  *************** *

23. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017134 (Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgcc	Protospacer
******  *************** *

24. spacer 1.7|41265|27|NC_016801|CRT matches to NZ_CP009803 (Streptomyces sp. FR-008 plasmid pSSFR1, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcaccagcggggatgctccgtacct	Protospacer
*****************  *****

25. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017101 (Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgcc	Protospacer
******  *************** *

26. spacer 1.7|41265|27|NC_016801|CRT matches to NZ_CP020471 (Rhodobacter blasticus strain 28/5 plasmid pRsa, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtatcc	Protospacer
******  ****************

27. spacer 1.7|41265|27|NC_016801|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggataaaccgttgtc	Protospacer
****.***********.****** *

28. spacer 1.7|41265|27|NC_016801|CRT matches to NZ_CP021924 (Acetobacter pasteurianus subsp. pasteurianus strain SRCM101468 plasmid pAP1468-2) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgttaaa	Protospacer
******  *************** ..*

29. spacer 1.7|41265|27|NC_016801|CRT matches to NC_013210 (Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgcc	Protospacer
******  *************** *

30. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017136 (Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgtcgcc	Protospacer
******  *************** *

31. spacer 1.7|41265|27|NC_016801|CRT matches to MK977714 (Corynebacterium phage Bran, complete genome) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggatgagccgtttgc	Protospacer
****.*************.****  *

32. spacer 1.7|41265|27|NC_016801|CRT matches to NC_048780 (Corynebacterium phage StAB, complete genome) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggatgagccgtttgc	Protospacer
****.*************.****  *

33. spacer 1.7|41265|27|NC_016801|CRT matches to MK977706 (Corynebacterium phage Dina, complete genome) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggatgagccgtttgc	Protospacer
****.*************.****  *

34. spacer 1.7|41265|27|NC_016801|CRT matches to MH926061 (Corynebacterium phage Troy, complete genome) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggatgagccgtttgc	Protospacer
****.*************.****  *

35. spacer 1.7|41265|27|NC_016801|CRT matches to NC_048789 (Corynebacterium phage Stiles, complete genome) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggatgagccgtttgt	Protospacer
****.*************.****  *

36. spacer 1.7|41265|27|NC_016801|CRT matches to NC_048069 (Corynebacterium phage SamW, complete genome) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggatgagccgtttgc	Protospacer
****.*************.****  *

37. spacer 1.7|41265|27|NC_016801|CRT matches to NC_048790 (Corynebacterium phage Lederberg, complete genome) position: , mismatch: 5, identity: 0.815

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggatgagccgtttgc	Protospacer
****.*************.****  *

38. spacer 1.4|41073|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026518 (Deinococcus sp. NW-56 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.786

ccccgcaccgtggggcgctggggaggtc	CRISPR spacer
ggcgacaccgtggggcgctggggcggtg	Protospacer
  * .****************** ***

39. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017130 (Acetobacter pasteurianus IFO 3283-26 plasmid pAPA26-013, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgttcag	Protospacer
******  ***************  ..

40. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017134 (Acetobacter pasteurianus IFO 3283-32 plasmid pAPA32-012, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgttcag	Protospacer
******  ***************  ..

41. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017101 (Acetobacter pasteurianus IFO 3283-03 plasmid pAPA03-010, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgttcag	Protospacer
******  ***************  ..

42. spacer 1.7|41265|27|NC_016801|CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcgccagcggggataaaccgtgttg	Protospacer
****.***********.******.  .

43. spacer 1.7|41265|27|NC_016801|CRT matches to NC_013210 (Acetobacter pasteurianus IFO 3283-01 plasmid pAPA01-011, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgttcag	Protospacer
******  ***************  ..

44. spacer 1.7|41265|27|NC_016801|CRT matches to NC_017136 (Acetobacter pasteurianus IFO 3283-12 plasmid pAPA12-014, complete sequence) position: , mismatch: 6, identity: 0.778

ccgcaccagcggggatgaaccgtagga	CRISPR spacer
ccgcacacgcggggatgaaccgttcag	Protospacer
******  ***************  ..

45. spacer 1.1|40881|28|NC_016801|CRISPRCasFinder,CRT matches to NZ_CP036351 (Planctomycetes bacterium K2D plasmid pK2D_1, complete sequence) position: , mismatch: 7, identity: 0.75

atgatacgcgggctgatgcgcggcatgc	CRISPR spacer
tggatacgcgggctgaagggcggcacca	Protospacer
  ************** * ******.

46. spacer 1.4|41073|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 7, identity: 0.75

ccccgcaccgtggggcgctggggaggtc	CRISPR spacer
ttgcgcaccgtggggcgcaggcgagggt	Protospacer
.. *************** ** **** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

136029 : 188104

Corynebacterium_phage(90.91%)

head,protease,integrase,holin,portal,transposase,capsid

attL 131385:131401|attR 194353:194369

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
131385:131401	attL	NA	NA	NA	NA
WP_014306303.1\|136029_137256_-\|integrase	site-specific integrase	A0A1W6JRD7	Corynebacterium_phage	5.4e-216	90.0
WP_014306304.1\|137355_138378_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_014318489.1\|138389_138953_-	hypothetical protein	NA	NA	NA	NA
WP_010934089.1\|139047_139455_-	ImmA/IrrE family metallo-endopeptidase	A0A1W6JRC2	Corynebacterium_phage	1.7e-73	99.3
WP_014318490.1\|139464_139956_-	hypothetical protein	A0A1W6JRB0	Corynebacterium_phage	2.6e-68	84.7
WP_010934091.1\|140069_140312_+	helix-turn-helix transcriptional regulator	A0A1W6JRC7	Corynebacterium_phage	1.6e-34	98.7
WP_016830425.1\|140358_140826_+	hypothetical protein	NA	NA	NA	NA
WP_014318491.1\|141049_141430_-	hypothetical protein	NA	NA	NA	NA
WP_014318492.1\|141617_141887_-	hypothetical protein	NA	NA	NA	NA
WP_003850201.1\|141977_142796_+	phage antirepressor Ant	A0A1W6JRI1	Corynebacterium_phage	9.2e-135	87.5
WP_003850203.1\|142815_143016_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003850204.1\|143012_143255_+	hypothetical protein	A0A1W6JRC8	Corynebacterium_phage	8.4e-20	59.0
WP_003850206.1\|143266_143491_+	hypothetical protein	A0A1W6JRD0	Corynebacterium_phage	4.9e-06	44.4
WP_003850207.1\|143487_143634_+	hypothetical protein	NA	NA	NA	NA
WP_003850213.1\|143903_144053_+	hypothetical protein	NA	NA	NA	NA
WP_003850214.1\|144049_144751_+	hypothetical protein	NA	NA	NA	NA
WP_003850217.1\|145186_146395_+	hypothetical protein	A0A220NQT1	Corynebacterium_phage	2.6e-133	66.2
WP_003850220.1\|146387_146975_+	hypothetical protein	A0A1W6JRC6	Corynebacterium_phage	1.0e-58	59.5
WP_003850222.1\|147059_147377_+	HNH endonuclease	A0A1W6JRD4	Corynebacterium_phage	1.4e-51	100.0
WP_003850225.1\|147529_147874_+	hypothetical protein	A0A1W6JRH9	Corynebacterium_phage	3.5e-19	50.5
WP_014318493.1\|147863_149465_+	hypothetical protein	A0A1W6JRF6	Corynebacterium_phage	9.1e-163	77.2
WP_010934105.1\|149477_150728_+\|portal	phage portal protein	A0A1W6JRE1	Corynebacterium_phage	2.5e-224	93.0
WP_014318494.1\|150724_151768_+\|head,protease	HK97 family phage prohead protease	A0A1W6JRD9	Corynebacterium_phage	2.6e-182	91.7
WP_014318495.1\|151764_153015_+\|capsid	phage major capsid protein	A0A1W6JRF1	Corynebacterium_phage	4.4e-205	88.9
WP_003850234.1\|153014_153215_+	hypothetical protein	A0A1W6JRE2	Corynebacterium_phage	2.3e-15	65.2
WP_003850235.1\|153236_153719_+	hypothetical protein	A0A1W6JRD8	Corynebacterium_phage	1.6e-83	93.8
WP_010934108.1\|153715_154078_+	hypothetical protein	A0A1W6JRD5	Corynebacterium_phage	3.6e-59	93.3
WP_014318496.1\|154070_154337_+	hypothetical protein	A0A1W6JRE6	Corynebacterium_phage	6.8e-39	95.5
WP_010934110.1\|154326_154704_+	hypothetical protein	A0A1W6JRI9	Corynebacterium_phage	1.1e-58	88.0
WP_014318497.1\|154732_155680_+	hypothetical protein	A0A1W6JRH0	Corynebacterium_phage	1.5e-152	84.1
WP_010934112.1\|155777_156155_+	hypothetical protein	A0A1W6JRK1	Corynebacterium_phage	2.7e-57	91.2
WP_010934113.1\|156316_156526_+	hypothetical protein	A0A1W6JRF2	Corynebacterium_phage	9.1e-31	88.4
WP_014318498.1\|156538_162181_+	hypothetical protein	A0A1W6JRG1	Corynebacterium_phage	0.0e+00	82.2
WP_014318499.1\|162190_162943_+	hypothetical protein	A0A1W6JRF0	Corynebacterium_phage	2.9e-127	87.6
WP_014318500.1\|162943_163804_+	hypothetical protein	Q37921	Corynephage	2.4e-165	100.0
WP_014318501.1\|163803_164919_+	hypothetical protein	Q37922	Corynephage	3.8e-168	100.0
WP_014318502.1\|164918_166115_+	hypothetical protein	A0A1W6JRF8	Corynebacterium_phage	1.7e-49	51.1
WP_014306320.1\|166503_167241_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JRK9	Corynebacterium_phage	3.6e-138	92.2
WP_014306321.1\|167240_167477_+\|holin	holin	A0A1W6JRG0	Corynebacterium_phage	2.5e-29	88.5
WP_014306322.1\|167482_167947_+	hypothetical protein	A0A1W6JRF4	Corynebacterium_phage	1.5e-57	73.5
WP_010934122.1\|167943_168282_+	hypothetical protein	A0A1W6JRH1	Corynebacterium_phage	1.2e-48	88.4
WP_003850266.1\|168631_170314_+	diphtheria toxin	A7UH54	Corynephage	0.0e+00	98.0
WP_014318503.1\|170875_172282_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_014318504.1\|172278_173643_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_021334768.1\|173733_174627_+	pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA	NA	NA	NA
WP_014318506.1\|174620_175178_+	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA	NA	NA	NA
WP_014318507.1\|175257_178506_-	putative surface-anchored fimbrial subunit	NA	NA	NA	NA
WP_014318508.1\|179040_179979_-	class C sortase	NA	NA	NA	NA
WP_014318509.1\|180651_182364_+	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_047928480.1\|182515_183454_+	class C sortase	NA	NA	NA	NA
WP_014318511.1\|183453_184245_+	hypothetical protein	NA	NA	NA	NA
WP_014318512.1\|184323_187431_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_014318513.1\|187798_188104_-\|transposase	transposase	NA	NA	NA	NA
194353:194369	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1107322 : 1124527

Corynebacterium_phage(91.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014318990.1\|1107322_1108279_+	hypothetical protein	A0A220NQQ6	Corynebacterium_phage	5.1e-52	42.1
WP_014318991.1\|1108426_1108846_+	hypothetical protein	A0A220NQP7	Corynebacterium_phage	6.3e-15	42.6
WP_014318992.1\|1109111_1109270_+	hypothetical protein	NA	NA	NA	NA
WP_014318993.1\|1109280_1114044_+	transglycosylase SLT domain-containing protein	A0A220NQR0	Corynebacterium_phage	5.7e-120	38.6
WP_014318994.1\|1114044_1114920_+	hypothetical protein	A0A220NQR1	Corynebacterium_phage	4.3e-82	54.5
WP_014318995.1\|1114919_1116575_+	hypothetical protein	A0A220NQQ5	Corynebacterium_phage	7.9e-194	56.7
WP_014318996.1\|1116574_1116994_+	DUF2744 domain-containing protein	A0A220NQQ4	Corynebacterium_phage	1.8e-38	58.5
WP_014318997.1\|1116986_1117877_+	hypothetical protein	A0A1W6JQC3	Corynebacterium_phage	1.7e-54	52.3
WP_167596969.1\|1118981_1119851_+	hypothetical protein	A0A1W6JQD7	Corynebacterium_phage	1.2e-12	34.8
WP_014318999.1\|1120194_1120986_+	hypothetical protein	A0A1W6JQE1	Corynebacterium_phage	3.1e-23	37.0
WP_174510714.1\|1121154_1122528_+	C39 family peptidase	A7IYC3	Corynebacterium_phage	7.6e-57	55.4
WP_014319001.1\|1122530_1122893_+	hypothetical protein	NA	NA	NA	NA
WP_041740497.1\|1122898_1123336_+	hypothetical protein	NA	NA	NA	NA
WP_134870501.1\|1123328_1123682_+	hypothetical protein	A0A1W6JQC8	Corynebacterium_phage	3.7e-24	49.1
WP_014319003.1\|1123732_1124527_-	hypothetical protein	A0A1D8EU84	Propionibacterium_phage	7.0e-15	29.0

DBSCAN-SWA_3

1139342 : 1149733

Gordonia_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014319035.1\|1139342_1139774_-	dUTP diphosphatase	M1HNR1	Paramecium_bursaria_Chlorella_virus	4.2e-22	39.7
WP_014319036.1\|1139775_1140132_-	hypothetical protein	A0A088FRI3	Mycobacterium_phage	3.1e-31	54.4
WP_014319037.1\|1140519_1140687_-	hypothetical protein	NA	NA	NA	NA
WP_014319038.1\|1140679_1141129_-	hypothetical protein	NA	NA	NA	NA
WP_158308755.1\|1141125_1141278_-	hypothetical protein	NA	NA	NA	NA
WP_014319040.1\|1141739_1141937_-	hypothetical protein	NA	NA	NA	NA
WP_014319041.1\|1141955_1142471_-	single-stranded DNA-binding protein	A0A0U4B2E8	Arthrobacter_phage	9.4e-45	69.1
WP_014319042.1\|1142533_1143463_-	recombinase RecT	A0A1B3AZ29	Gordonia_phage	4.5e-29	37.0
WP_014319044.1\|1143684_1144710_-	YqaJ viral recombinase family protein	A0A1B3AZ40	Gordonia_phage	8.8e-26	34.0
WP_014319045.1\|1144850_1145153_-	hypothetical protein	NA	NA	NA	NA
WP_014319046.1\|1145297_1145564_-	hypothetical protein	A0A2P1A0Q4	Gordonia_phage	4.0e-07	37.8
WP_014319047.1\|1145560_1146412_-	DNA-damage-inducible protein D	A0A1C9M020	Mycobacterium_phage	1.3e-46	43.8
WP_014319048.1\|1146413_1146599_-	hypothetical protein	NA	NA	NA	NA
WP_014319049.1\|1147033_1149733_+	DNA polymerase I	F8WQ35	Bacillus_phage	1.3e-47	33.7

DBSCAN-SWA_4

2056818 : 2161546

Staphylococcus_phage(16.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014307324.1\|2056818_2059284_-\|protease	ATP-dependent zinc metalloprotease FtsH	G9E4U6	Ostreococcus_lucimarinus_virus	4.0e-109	41.7
WP_014308708.1\|2059415_2060003_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	5.8e-14	30.8
WP_014319349.1\|2060023_2060902_-\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_014319350.1\|2060894_2062175_-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
WP_003852922.1\|2062209_2062686_+	inorganic diphosphatase	NA	NA	NA	NA
WP_014319351.1\|2062842_2063139_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	2.5e-10	40.5
WP_014319352.1\|2063214_2063676_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_014319353.1\|2063676_2067519_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	3.3e-41	28.0
WP_014303879.1\|2067700_2067913_-	hypothetical protein	NA	NA	NA	NA
WP_014319354.1\|2068272_2069124_+	hypothetical protein	NA	NA	NA	NA
WP_014319356.1\|2070230_2071127_-	polyphosphate kinase 2	NA	NA	NA	NA
WP_014319357.1\|2071492_2072329_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_021335201.1\|2072600_2072774_-	hypothetical protein	NA	NA	NA	NA
WP_014319359.1\|2073388_2075029_-	chaperonin GroEL	A0A240F779	uncultured_virus	2.2e-148	54.0
WP_041740558.1\|2076442_2077255_+	hypothetical protein	NA	NA	NA	NA
WP_014319011.1\|2080936_2082286_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.4e-34	36.6
WP_014319368.1\|2082656_2082794_+	hypothetical protein	NA	NA	NA	NA
WP_014319369.1\|2082898_2084272_+	dipeptidase	NA	NA	NA	NA
WP_014319371.1\|2084683_2085844_+	DUF2029 domain-containing protein	NA	NA	NA	NA
WP_014311565.1\|2085786_2086866_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_014319372.1\|2086862_2087411_-	LytR C-terminal domain-containing protein	NA	NA	NA	NA
WP_003852983.1\|2087413_2087617_-	DUF3263 domain-containing protein	NA	NA	NA	NA
WP_003852985.1\|2087615_2088179_+	peptide deformylase	A0A2I7R224	Vibrio_phage	1.4e-12	38.2
WP_010935526.1\|2088195_2089083_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014319373.1\|2089087_2089795_+	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_014319374.1\|2089791_2091225_+	cardiolipin synthase	NA	NA	NA	NA
WP_003852994.1\|2091650_2092388_-	multidrug ABC transporter permease	NA	NA	NA	NA
WP_041740565.1\|2092371_2093268_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.8e-30	37.2
WP_014319376.1\|2093302_2094559_+	hypothetical protein	NA	NA	NA	NA
WP_014319377.1\|2094555_2095503_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_014319378.1\|2095499_2097662_+	serine/threonine protein kinase	A0A1V0SBL0	Catovirus	3.5e-08	24.5
WP_003853004.1\|2097681_2098881_-	acetate kinase	NA	NA	NA	NA
WP_014319379.1\|2098881_2100249_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_014319380.1\|2100511_2101870_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014319381.1\|2101876_2102293_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014319382.1\|2102289_2103186_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_003853372.1\|2103217_2103718_+	phosphoribosyltransferase	NA	NA	NA	NA
WP_014319383.1\|2103738_2104626_+	hypothetical protein	NA	NA	NA	NA
WP_014319384.1\|2104622_2106053_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_003853379.1\|2106053_2106221_-	hypothetical protein	NA	NA	NA	NA
WP_014303923.1\|2106434_2107724_-	adenylosuccinate synthase	A0A160ER07	Powai_lake_megavirus	1.5e-67	35.4
WP_021335209.1\|2107818_2108028_+	hypothetical protein	NA	NA	NA	NA
WP_021335210.1\|2108297_2109134_+	hypothetical protein	NA	NA	NA	NA
WP_014319386.1\|2109130_2110258_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_014319387.1\|2110370_2111504_+	hypothetical protein	NA	NA	NA	NA
WP_014307372.1\|2111595_2112720_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_014319388.1\|2113188_2113989_+	DUF3800 domain-containing protein	NA	NA	NA	NA
WP_041740567.1\|2114277_2115390_+	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	NA	NA	NA	NA
WP_010935552.1\|2115433_2116225_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_158308757.1\|2118600_2118738_+	hypothetical protein	NA	NA	NA	NA
WP_014317148.1\|2119272_2120061_-	hypothetical protein	NA	NA	NA	NA
WP_014319392.1\|2120060_2120777_-	ABC transporter ATP-binding protein	A0A2K9L0W2	Tupanvirus	1.8e-09	29.2
WP_014319395.1\|2123907_2124378_-	hypothetical protein	NA	NA	NA	NA
WP_021335215.1\|2124416_2124617_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_158308758.1\|2124726_2124879_-\|transposase	transposase	Q6H9S3	Enterobacteria_phage	3.0e-07	47.8
WP_047928725.1\|2124992_2126396_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-28	34.4
WP_014317154.1\|2126281_2127100_-\|transposase	IS3 family transposase	A0A1B3AZE5	Gordonia_phage	3.3e-36	41.0
WP_014319398.1\|2127099_2127414_-\|transposase	transposase	A0A2P1JR43	Mycobacterium_phage	3.0e-09	41.8
WP_014319399.1\|2127466_2127664_+	hypothetical protein	NA	NA	NA	NA
WP_014319400.1\|2127663_2128002_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_077393419.1\|2127988_2128543_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	2.9e-23	37.1
WP_014307386.1\|2129056_2130139_+	DtxR family transcriptional regulator	NA	NA	NA	NA
WP_014303371.1\|2130181_2131327_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_014319401.1\|2131308_2136843_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	7.1e-37	27.9
WP_014319402.1\|2136835_2137444_+	VOC family protein	NA	NA	NA	NA
WP_014303368.1\|2137440_2139072_+	AMP-binding protein	NA	NA	NA	NA
WP_014319403.1\|2139084_2146656_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.4e-32	29.3
WP_014319404.1\|2146747_2147374_+	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_014303365.1\|2147373_2148120_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_014303364.1\|2148116_2149595_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.7e-15	29.9
WP_014303363.1\|2149598_2151323_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.1e-28	26.2
WP_014319405.1\|2151322_2153089_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.1e-31	26.1
WP_014303361.1\|2153116_2153866_-	thioesterase	NA	NA	NA	NA
WP_014319406.1\|2153898_2155077_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_014303359.1\|2155123_2155753_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_014303358.1\|2156174_2157239_+	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	4.1e-18	33.3
WP_014303357.1\|2157235_2157997_+	ABC transporter permease	NA	NA	NA	NA
WP_014303356.1\|2157989_2158811_+	ABC transporter permease	NA	NA	NA	NA
WP_014319407.1\|2159312_2159636_-\|transposase	transposase	Q8W6R2	Burkholderia_virus	4.4e-24	60.7
WP_047928725.1\|2159616_2161020_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-28	34.4
WP_014318596.1\|2161210_2161546_-\|transposase	IS3 family transposase	A0A2P1JR32	Mycobacterium_phage	6.2e-13	45.2

Anti-CRISPR protein detection

Acr_ID: NC_016801.1|WP_014318999.1|1120194_1120986_+|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_016801.1|WP_014318999.1|1120194_1120986_+|hypothetical-protein

1120194_1120986_+

263 aa aa

1107322-1124527

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_016801_1	TypeII	1.5\|41137\|28\|NC_016801\|CRISPRCasFinder,CRT,PILER-CR	41137-41164	28	1112560-1112587	0

1. spacer 1.5|41137|28|NC_016801|CRISPRCasFinder,CRT,PILER-CR matches to NC_016801 position: 1112560-1112587, mismatch: 0

ggtggcgttaactggggtgactgctccg	CRISPR spacer
ggtggcgttaactggggtgactgctccg	Protospacer
****************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_016801

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information