CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016785	Corynebacterium diphtheriae CDCE 8392, complete sequence	2 crisprs	cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,csa3,cas3,WYL,cas4,DinG	0	0	1	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_016785_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016785_1

39026-39783

TypeI-E

I-E

Consensus_repeat	Method
GTTTTCCCCGCACCAGCGGGGATGAGCC	CRISPRCasFinder
GTTTTCCCCGCACCAGCGGGGATGAGCC	CRT
GTTTTCCCCGCACCAGCGGGGATGAGCC	PILER-CR

12 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

The CRISPR arrays of NC_016785_1

>merge|NC_016785|1|39026-39783|CRISPRCasFinder,CRT,PILER-CR
GTTTTCCCCGCACCAGCGGGGATGAGCCGCCACCAATCAGCCCTACGAATCGGCAAACACAGTTTTCCCCGCACCAGCGGGGATGAGCCCTCGGAGGAGCGGGCACCGACGTTACGGAGCTTGTTTTCCCCGCACCAGCGGGGATGAGCCCTTAAAATCGGCTCGCTATTTCTCCGGGTACGAGTTTTCCCCGCACCAGCGGGGATGAGCCGATTGATAAGACAGCGCTAGACCTGCCTGCACCGTTTTCCCCGCACCAGCGGGGATGAGCCCAAGCAGAAGAGCGCGACGGCAATGTGGTTCCCGTTTTCCCCGCACCAGCGGGGATGAGCCGCGTGTTTGATGGAGTGCAGTTCTGGGAATTAGGTTTTCCCCGCACCAGCGGGGATGAGCCCCCGCACCAATCGTTTGTGGATCGGTATCCAACGTTTTCCCCGCACCAGCGGGGATGAGCCGCACCTGTATAAGTCATTATTTATTTCCCTTTCGTTTTCCCCGCACCAGCGGGGATGAGCCCATCGGCCGGTAGTGGGTCGCCTTCCGCGCCCCGTTTTCCCCGCACCAGCGGGGAGGAGCCCCAAACCCATTCCCACCAGAATTACGCTCATTCGTTTTCCCCGCACCAGCGGGGATGAGCCGACGACCGTGGGAACCGCGAGGATAAATAGCAGGTTTTCCCGCACCAGCGGGGATGAGCCGACGACCGTGGGAACCGCGAGGATAAATAGCAGGTTTTCCCGCACCAGCGGGGATGAGCC

>NC_016785|1|1|39026-39783|CRISPRCasFinder
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCCACCAATCAGCCCTACGAATCGGCAAACACA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCGGAGGAGCGGGCACCGACGTTACGGAGCTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTTAAAATCGGCTCGCTATTTCTCCGGGTACGA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GATTGATAAGACAGCGCTAGACCTGCCTGCACC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAAGCAGAAGAGCGCGACGGCAATGTGGTTCCC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCGTGTTTGATGGAGTGCAGTTCTGGGAATTAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCCGCACCAATCGTTTGTGGATCGGTATCCAAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACCTGTATAAGTCATTATTTATTTCCCTTTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATCGGCCGGTAGTGGGTCGCCTTCCGCGCCCC
GTTTTCCCCGCACCAGCGGGGAGGAGCC	CCAAACCCATTCCCACCAGAATTACGCTCATTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GACGACCGTGGGAACCGCGAGGATAAATAGCA
GGTTTTCCCGCACCAGCGGGGATGAGCC	GACGACCGTGGGAACCGCGAGGATAAATAGCA
GGTTTTCCCGCACCAGCGGGGATGAGCC

>NC_016785|1|1|39026-39783|CRT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCCACCAATCAGCCCTACGAATCGGCAAACACA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCGGAGGAGCGGGCACCGACGTTACGGAGCTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTTAAAATCGGCTCGCTATTTCTCCGGGTACGA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GATTGATAAGACAGCGCTAGACCTGCCTGCACC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAAGCAGAAGAGCGCGACGGCAATGTGGTTCCC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCGTGTTTGATGGAGTGCAGTTCTGGGAATTAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCCGCACCAATCGTTTGTGGATCGGTATCCAAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACCTGTATAAGTCATTATTTATTTCCCTTTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATCGGCCGGTAGTGGGTCGCCTTCCGCGCCCC
GTTTTCCCCGCACCAGCGGGGAGGAGCC	CCAAACCCATTCCCACCAGAATTACGCTCATTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GACGACCGTGGGAACCGCGAGGATAAATAGCA
GGTTTTCCCGCACCAGCGGGGATGAGCC	GACGACCGTGGGAACCGCGAGGATAAATAGCA
GGTTTTCCCGCACCAGCGGGGATGAGCC

>NC_016785|1|1|39087-39783|PILER-CR
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTCGGAGGAGCGGGCACCGACGTTACGGAGCTT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTTAAAATCGGCTCGCTATTTCTCCGGGTACGA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GATTGATAAGACAGCGCTAGACCTGCCTGCACC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAAGCAGAAGAGCGCGACGGCAATGTGGTTCCC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCGTGTTTGATGGAGTGCAGTTCTGGGAATTAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCCGCACCAATCGTTTGTGGATCGGTATCCAAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACCTGTATAAGTCATTATTTATTTCCCTTTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATCGGCCGGTAGTGGGTCGCCTTCCGCGCCCC
GTTTTCCCCGCACCAGCGGGGAGGAGCC	CCAAACCCATTCCCACCAGAATTACGCTCATTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	GACGACCGTGGGAACCGCGAGGATAAATAGCA
GGTTTTCCCGCACCAGCGGGGATGAGCC	GACGACCGTGGGAACCGCGAGGATAAATAGCA
GGTTTTCCCGCACCAGCGGGGATGAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016785.1\|WP_014306228.1\|33347_34358_+\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|235528
NC_016785.1\|WP_014306229.1\|34354_35170_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|237797
NC_016785.1\|WP_155760674.1\|35292_35463_+\|hypothetical-protein	unknown	unknown	unknown
NC_016785.1\|WP_014306225.1\|30623_31292_+\|thiamine-phosphate-synthase	unknown	unknown	gnl\|CDD\|234590
NC_016785.1\|WP_014306239.1\|48568_50098_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016785.1\|WP_014306237.1\|45809_46157_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NC_016785.1\|WP_014306227.1\|32562_33348_+\|thiazole-synthase	unknown	unknown	gnl\|CDD\|234687
NC_016785.1\|WP_014306232.1\|40010_41684_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NC_016785.1\|WP_014306234.1\|42328_43462_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NC_016785.1\|WP_014302665.1\|43466_44171_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|378243
NC_016785.1\|WP_014306238.1\|46550_48572_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016785.1\|WP_049791608.1\|44892_45780_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|187850
NC_016785.1\|WP_014306231.1\|35987_38789_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NC_016785.1\|WP_014306226.1\|31288_32377_+\|glycine-oxidase-ThiO	unknown	unknown	gnl\|CDD\|274092
NC_016785.1\|WP_014306224.1\|28840_30640_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_016785.1\|WP_014306235.1\|44172_44838_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NC_016785.1\|WP_014306233.1\|41687_42314_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NC_016785.1\|WP_014302657.1\|32360_32561_+\|sulfur-carrier-protein-ThiS	unknown	unknown	gnl\|CDD\|273754
NC_016785.1\|WP_014307720.1\|27147_27765_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NC_016785.1\|WP_003849883.1\|46164_46434_-\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907

Protein	Function_ID	Function_description	E-value
NC_016785.1\|WP_014306228.1\|33347_34358_+\|ThiF-family-adenylyltransferase	gnl\|CDD\|235528	PRK05600, PRK05600, thiamine biosynthesis protein ThiF; Validated.	0
NC_016785.1\|WP_014306229.1\|34354_35170_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|237797	PRK14713, PRK14713, bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.	8.59344e-111
NC_016785.1\|WP_014306225.1\|30623_31292_+\|thiamine-phosphate-synthase	gnl\|CDD\|234590	PRK00043, thiE, thiamine phosphate synthase.	4.01452e-63
NC_016785.1\|WP_014306239.1\|48568_50098_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.51573e-107
NC_016785.1\|WP_014306237.1\|45809_46157_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.45981e-42
NC_016785.1\|WP_014306227.1\|32562_33348_+\|thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	1.88796e-147
NC_016785.1\|WP_014306232.1\|40010_41684_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	4.80373e-108
NC_016785.1\|WP_014306234.1\|42328_43462_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	9.06672e-159
NC_016785.1\|WP_014302665.1\|43466_44171_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	8.43322e-41
NC_016785.1\|WP_014306238.1\|46550_48572_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.31606e-121
NC_016785.1\|WP_049791608.1\|44892_45780_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187850	cd09719, Cas1_I-E, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.08889e-124
NC_016785.1\|WP_014306231.1\|35987_38789_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	1.72196e-93
NC_016785.1\|WP_014306226.1\|31288_32377_+\|glycine-oxidase-ThiO	gnl\|CDD\|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	3.71748e-127
NC_016785.1\|WP_014306224.1\|28840_30640_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_016785.1\|WP_014306235.1\|44172_44838_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	3.27959e-78
NC_016785.1\|WP_014306233.1\|41687_42314_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	4.9054e-32
NC_016785.1\|WP_014302657.1\|32360_32561_+\|sulfur-carrier-protein-ThiS	gnl\|CDD\|273754	TIGR01683, thiamine_biosynthesis_protein_ThiS, thiamine biosynthesis protein ThiS. This model represents ThiS, a small, ubiquitin-like thiamine biosynthesis protein related to MoaD, a molybdenum cofactor biosynthesis protein. Both proteins are involved in sulfur transfer. ThiS has a conserved Gly-Gly C-terminus that is modified, in reactions requiring ThiI, ThiF, IscS, and a sulfur atom from Cys, into the thiocarboxylate that provides the sulfur for thiazole biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	8.21875e-20
NC_016785.1\|WP_014307720.1\|27147_27765_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	2.72806e-26
NC_016785.1\|WP_003849883.1\|46164_46434_-\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	2.52021e-46

>NC_016785.1|WP_014306231.1|35987_38789_+|CRISPR-associated-helicase/endonuclease-Cas3
MSVVDQADQWRRARSVQAYSLWAKSGSEDLYLRLPQHLIDAACVAEWLWNNWVSDSLKSTLSAAWRLPAEEVGRLYTFYAGTHDVGKATISFQRLVEKTSHGNYLLGPVREAGLSLQWTLNEGEGKKFPHGMASALIIAAWLEKHDIDPSSAARLSFIADAHHGFASDEELYRSHEDTLDYYPPEWLVVHAEILDSMAEITDIGETLEELADQSTPSAPAMQIMTGLVIMADWIASDEKAFPYVCDSSQHDRVVEGMSHVNLPPAWVPTDVPDNVETLFRDTFTWPDSYQVRPVQRAAVAVARAVQDPTLIIIEAPTGEGKTEAGLATSHILGQKTGAQGIFFAAPTMSTANGLFERTKNWAQCTSSRGEVASLYLAHSKNKLSLPFQSLRFTSIGEDDHLEKHGSVVASQWLSGRHRGILSDFVVGTVDQVLMMALQVRFSMLRHVGLAGKIVIIDEVHAYDAYMSQYLYLTLQWLAKYGVSVILMSATLPPQQRARLVNAYASQVCKKADASALNSDAYPLITAVNKKGISVTEVPQENSDTTIKIRCIDDSLPALGGMFSDLLVDGGIALVICNTIRRAQQAYDSLKAIFPDEVELHHAAFIATQRSEKEDALRESLGPHASRGEDRPWRRIVVATQVAEQSLDIDADVLVTDIAPIDLIIQRAGRLHRHERPHSDRPEILGQPQIFIRGINNEEISGEVPEFDGGAAAIYGEKILYATVAYLPDEFHRPSDVPKLVKNVYSDTPCIPENWKEQWEQACVKAKENYEKSVRKAQTFSFPQPHMARTLRDLFKQQHSNSVDKNEESGSAQVRDAEFSIEVVALLKNEYGYHPFGRKEEIENGRELTWKEAEALAGNTVRLPARMTRRDSDFNAVIDSLEAQTPPEWQRSGLLKGQVALLFDERGEARVGRFLVRYTNERGLEVEVCPKEDA
>NC_016785.1|WP_155760674.1|35292_35463_+|hypothetical-protein
MPSSIPSAAPQSTVIVTVIEAESVEPIEPHMRAAWKAMSKRRKDTLAYIRHTINAL
>NC_016785.1|WP_014306229.1|34354_35170_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MTPHILTIAGSDPSGGAGIQADLKSIMAAGGYGMAAITALTAQNTCGVTAIHTPPTEFLSQQLRAISDDITIHAIKIGMIGSSDAATAIATWLDQLHHTPIVVLDPVMVATSGSVLGERHYFEPLLHHATVITPNLPELAVLANNHDPEQAEHVARSLAEQYDCAVLLKGGHRHGTNDLGNTWITASGPQFHAPSPRIHTTNTHGTGCSLSSALATRLAIEPPEPALHWATTWLNGAIAHGSDLNVGHGNGPVDHSYRLGEYSANCNTIES
>NC_016785.1|WP_014306228.1|33347_34358_+|ThiF-family-adenylyltransferase
MLDELERQRVARQLRLPGFGIEQQEKLNKGRVLVIGAGGLGSPALQSLAAAGVGSIRLVDNDTVDVSNIQRQILFGVGDVGRSKVHVAAERLRAIQPGIRIDARTERLTAHNAHELAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHMGVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTVQPGAVTTYNALTSTFRTYTVGRDPLRSAARTLYTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWNDTTAIQHALDNITTDNVVVVCASGIRSAAFIEQFAHLNPHLTFHNVPSGINELP
>NC_016785.1|WP_014306227.1|32562_33348_+|thiazole-synthase
MLTIADRSFQSHLIMGTGGASSFDTLEKSLIASGTELTTVAMRRHAAHTGAHGESVFELMQRLNITPLPNTAGCRTARDAILTAQLAREALKTSWIKVEVIADDTTLLPDVLELIDATETLTNDGFTVLAYTSDDPVVAQRLEDAGAAAVMPLGSPIGTGLGILNPHNIELICSRATVPVLLDAGIGTASDATLAMELGCSGVLLASAINRCINPITMATAMKHAVEAGRLAREAGRIPRREHAVASSSFEGLASWADEVL
>NC_016785.1|WP_014302657.1|32360_32561_+|sulfur-carrier-protein-ThiS
MDIYINDTLTTIESPQLTEIISNHCNGIRPGIAVAINQRVIPRSQWDTTTVTAGDHLDILTAVQGG
>NC_016785.1|WP_014306226.1|31288_32377_+|glycine-oxidase-ThiO
MKIAVVGGGIVGLSTAFELSTRGYNVHVFDPNPASGASHFAGGMLAPAAEVQFQQDPLFPLMKRAGKLWPDMVRWVAQHTNLPTGYRTEGTLVVAADRADAEHLKQLRATQEAAGMDVRPIATRQARGLEPALGPRLSAAVHIPNDTQVAPRVFLTALLDALDDCGVEVTKEKITDLEPLYQQFDVVVLAAGLGAQHLSPIPLALRPVRGDILRVQTEPGAVNMVVRGWVNDRPIYIIPRANGEIAIGATSREDERDLPSVEGIYDLLRDAIRVVPGIVDSSLIEANVGVRPGTPDDLPYLGWASDRLIISTGYFRHGILLSSLGAHVTACLIDGTDPGIDLTACAPDRHHNERGTTHGHLH
>NC_016785.1|WP_014306225.1|30623_31292_+|thiamine-phosphate-synthase
MLPTPRWGRDFDPRCYFVTGTGSVDHIVDVARQAARAGAGLIQVRSKPIAARDLYILGREVARAVAEVNPRTRVLIDDRVDVALALMNNGEHIHGVHVGQDDLPVRHVRALLGDNAIIGLTTGTLELVRASRQVAEVIDYIGAGPFRPTPTKDSGRAPVGLAGYPPLVAESLVPVVAIGDVRPEDAADLAATGVAGVAIVRALMNSQDVATDVKLVLKGFAQ
>NC_016785.1|WP_014306224.1|28840_30640_+|phosphomethylpyrimidine-synthase-ThiC
MSAASANSATNPSAWENSEIHPKHSYSPIVSGDLEVPETEIQLDDSPTGPNDPVRIYRTRGPECDPTVGLKPLRAQWIDNREDTEEYAGRERNLADDGRSAQRRGAASLEWKGVKPAPRRAKQGKRVTQMHYARQGIITKEMEFVALREHMDPEFVRSEIARGRAIIPNNINHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLRWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTKRVTGIVSRGGSIMAGWCLAHHKESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSVADANDAAQFAELKTIGELARRAWEYDVQVMIEGPGHVPLNMVQENNELEQKWAHDAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWHDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFADKITDLGIPQVGGDAEAGMSAKSEEFVAQGSQLYSEVRDNAAHA
>NC_016785.1|WP_014307720.1|27147_27765_+|rhomboid-family-intramembrane-serine-protease
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPYSHGLGWLRMVGTVFLHSGPTHLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATVLLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLILIAVNVGYSLLMDGVSLWGHLGGLLTGCVLGIVLVIAQTTRGGKRG
>NC_016785.1|WP_014306232.1|40010_41684_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MASLLEIRWILALDTQGNQISVGIRDIFAGEVQVAYIQGESPAQDYAVMRLLLGIFWRAHSMDIDMDVEPFDFLEWFNKMRRQLARKGKDQVVLDYLDRYADRFELFDAKAPFMQVAGLHVASGEYKHITTIIPEAQDEYFSMRGGKERDSVSIEEAARWLVYVHAFDYSGIKSGAVGDSRVKGGRGYPIGTGWTGMTGGTLVKGEDLLDTLLLNTTLETLNDPEDRPVWERTAYGPGERAVVGENSQPQGPADLATWQSRRIRLIPEGDRVVGVIVCNGDKIPDAGANVLDDPMTPYRFSTNKSKKDHDVYYPRPYDVERTMWKALDALVVAETDGGFSAKEKAPKRPKNLASLAELAVQKANVPAVLNVDLVSVEYGPQASSVATTYASRMSMPVVLLLTEAKHLRGKVREIARATTQSAVALGQFSGNLLDAAGGEYAFQPAITDRVLAELEPRFNDWLERLRDISPEQAIQDNESLTDLEKAWQHTARSVIDQHARILLRGAGPKALAGRIQYRDADDHKGRVVSAAGYYRMLQRKLDEVLPLTVRKQEKEGE
>NC_016785.1|WP_014306233.1|41687_42314_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MAENKDALRAAVGATCHRLQEAYLGDRNSARHHSARATLAELRHGATVDIRKNPLGLEKVLFAMVGDFSDRLVGHGDNPSPSEEAAFVALTLFGVHMQSATSPVHIPQVSFASACGRLHSLGTSDSIKPRVDAMLLASQEQARLVHIRSLVTLLRANNIGFDYGLLARDLRALNDPKKRAGIQLRWGRDFAIGHFRNFNSTTNSTQTA
>NC_016785.1|WP_014306234.1|42328_43462_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTLVVDIHALQTVPPSLINRDDMGAPKTAIFGGVPRQRVSSQSWKRAVRRFFEDEIDKSTVGLRSRKLPENIVSRAIALGSDLTEDQILDGVRQLFKAAKISLVEPKAPKKGEELPEDAEKYPTTGYLLFLSPYQLDRAAQAVVDKNGEKFTKAEAEDILDTKHSVDMALFGRMLADAPAYNIDASVQVAHAISVHESQPEFDYFTAVDDVVEDAEETGAGMIGTTQMMSSTLYRFATVNVDGLVKNLEDTELAHEAVRMFIRAFAESMPTGKQNSFANNTLPELMYVAVRDTRSVSLVNAFEEPVAAADGSRRQAAATALAREERDIEEAYGMKPLASFVVALGELGTDFEELAEKVTLTELGEAVIRTLAAQEAK
>NC_016785.1|WP_014302665.1|43466_44171_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSYSLLLLLKGPLQSWGDESRYNTRATGNTPSKSGVIGLLAAAQGRQRTDSIEDLVALDFAVRVDQSGTLLRDYQTAQPWQKAPKANASLVTRHFLSDAAFVAAIGSEDKELLEGLQGHLRQPTYPLFLGRRSCPAPVNLDLGIVDKPVVEALMAHDTWHATSAHQQERSRDVELPIYRDGKPGEHGVPRQDVPLSFAQEHRRYGWRTVVYAGSKSIVNEKGTANDPFFEAVIS
>NC_016785.1|WP_014306235.1|44172_44838_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MATFTKVLINPARRQGRKYLTNPHMLHAAVMHGFPPDCDTSTERILWRLDERGHEHILYVVGPEKPTIDHIVEEAGWDVRPPQSADYDRLLSQLTKGQKWNFELVANPTHTIPVQGGKRGKVVAHSTAAKQLEWLHRKAESMGVSFGTLENSSAQVVGKKTLDFHRSRPNGERGDRVHLVTARFSGQLEVVDADKLRATLIGGVGRAKGYGCGLLTLARGQ
>NC_016785.1|WP_049791608.1|44892_45780_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MESRLSFLYVERAVINRDGNALTIKDQRGIAHVPATQLAVVLLGPGTKVTYAAMALLGDAGASVVWVGEKGVRYYAHGRPPAKTSRFAEAHARLWSNQRTRLRCARRMYDMRFPGEEISQLSLSQLRGREGARMKKIYAAEAQRTGVVWTRRNYDPQDFESGDPINRALTEGSAALYGIAHAVIVGLGFIPSLGIVHTGTDRAFVYDIADLYKAEISIPVAFEAVAAIPSGDDLNVRARIRDKVVSTRLMQRMVHDLQDLMEIPEEDAYSDVDLMLWSELEVIAAGVNLRSLLLV
>NC_016785.1|WP_014306237.1|45809_46157_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MIVLVVSAVPAGLRGDLTKWLMEISPGVFVGNPSARIRDLLWERTTELSKDGRALLIYSSNNEQGMEYRTHRHEWEPTDFDGLTLMMRPDNTKPSSYQRRTGWSIARNVRKNRGN
>NC_016785.1|WP_003849883.1|46164_46434_-|cell-division-protein-CrgA
MPKSKINHSSTAYTAGSTANRTPVKINSTGTPLWYKIIMFGLILAGLLWLIVNYLAGQDISFMTELGPWNYGIGFGLFIIGLLMTMGWR
>NC_016785.1|WP_014306238.1|46550_48572_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTDIVLVDRYRLGDVIGTGGMSEVYEATDVLLGRKVAVKMLRADLARDVNFRERFRREAQNSGKLNHPAIVAVYDTGETPRAGLNTPYIVMELVNGRTLRDIVREDGPLTPSQAAHTLIPVCHALQVSHDAGIIHRDIKPANVMITNTGAVKIMDFGIARALDDATSAMTQTSAVIGTAQYLSPEQARGKLADARSDVYALGCVLYETLTGKPPFEGETPFAVAYQHVQEDPVKPSEYIADLSPTAAINVDAVVLTAMSKHPGDRYQTAQEMCADLERLERNAVTDAARHYVTPTSFATQDPASTTVVPVTQVTELDHAEAGAGIGAGVVPAGAVAGSAAVAGAGGAHAAPRSSNRGLRILAAILAVLVLAVGAGFAIDHFGGGPFSQRSTVTIPKLQNSTQQDAVNQLEKLGLQVNVIEEPNPDIPRGKVIRTNPTDGSNVQRNSTVRLTISSGKEITEVPDLSGKNTADAVKILEAAGLLLDPTVREDSSDTVPKGEIIEVSPAAGSQVSRGSKVSITVSTGVETVRVPVITGMKWDQAEGNLTSLGFKPEVVRVDSVEPAGTVVAVPDEGAEVPKGSRVTVQISNGAMFTVPEITRQTIGDAVRILHDAGWNGNASRLIQAAKVPTVAVTDQNLIASQLPTPGTALRKDAPIEIRLYEFNLAALVPPAQH
>NC_016785.1|WP_014306239.1|48568_50098_-|serine/threonine-protein-kinase
MTQSQSPDPALQALVGSDYALQWVVGNGGMSTVWLADDLRNQREVAIKVLRPEFSDNEEFLSRFRNEALASEHIDSDNVVRTYDYREVTDDMGRTLCFIVMEYVRGESLADMLARKGRLEEDLALDVLEQAAHGLSIIHRMGMVHRDIKPGNLLITQNGQVKITDFGIAKAAAAVPLTRTGMVVGTAQYVSPEQAQGRDVTAATDVYSLGVVGYEMLVGQRPFTGDSSVSVAIAHINQAPPAMPTSVSAPARELIGIALRKDPAHRYADGNELALAVSATRMGQRPPQPKSAPLQHIAPQPAPTESTYALGATAQPTTVIPATGQVPAAPTAAPAAAAAYPASTVIPAGTPRQEPEKQSSGWGAGIVVGALAALLLGTAAWAASQGMFDDLFDKTSQSSESSVPPPPVTATVTETPTPQITTVVPEPLPTSSPEPTPSETKRTPDESHPSSDHQLPSVRPSHNGRPSSQAPHAPHAPTQDADQPAESPAPDTLDSLIENLNKLNQGGAQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_016785_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016785_2

1465451-1465563

Orphan

Consensus_repeat	Method
GCTGGTTTAGGAGCCGCAGGCTT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_016785_2

>merge|NC_016785|2|1465451-1465563|CRISPRCasFinder
GCTGGCTTTGGAGCCGGCTTCTTTTCTGCTGCCGGCTTAGGCGCAGCTGGTTTAGGAGCCGCAGGCTTAGCCGCTTGTTGCGGAGTTGCTGCTGGCTTAGGCGCTGCAGGTTT

>NC_016785|2|2|1465451-1465563|CRISPRCasFinder
GCTGGCTTTGGAGCCGGCTTCTT	TTCTGCTGCCGGCTTAGGCGCA
GCTGGTTTAGGAGCCGCAGGCTT	AGCCGCTTGTTGCGGAGTTGCT
GCTGGCTTAGGCGCTGCAGGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_016785.1\|WP_003851924.1\|1466486_1467485_-\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|237061
NC_016785.1\|WP_010935095.1\|1467481_1468036_-\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NC_016785.1\|WP_014307021.1\|1470863_1471610_+\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NC_016785.1\|WP_014307014.1\|1456720_1457692_-\|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl\|CDD\|235536
NC_016785.1\|WP_193350843.1\|1461718_1462303_-\|DHH-family-phosphoesterase	unknown	unknown	gnl\|CDD\|223691
NC_016785.1\|WP_014302055.1\|1462343_1462787_-\|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl\|CDD\|234787
NC_016785.1\|WP_003851917.1\|1459302_1460109_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|224327
NC_016785.1\|WP_010935099.1\|1472452_1473799_+\|YdiU-family-protein	unknown	unknown	gnl\|CDD\|234583
NC_016785.1\|WP_010935090.1\|1458613_1459306_-\|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl\|CDD\|225524
NC_016785.1\|WP_014307016.1\|1460155_1461475_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240541
NC_016785.1\|WP_014307022.1\|1471629_1472454_-\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|381169
NC_016785.1\|WP_010935096.1\|1468087_1468996_+\|DUF4439-domain-containing-protein	unknown	unknown	gnl\|CDD\|373114
NC_016785.1\|WP_014307013.1\|1455701_1456661_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|239116
NC_016785.1\|WP_014307020.1\|1469074_1470832_-\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236405
NC_016785.1\|WP_003851932.1\|1474946_1475456_-\|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|376440
NC_016785.1\|WP_003851911.1\|1455260_1455530_-\|30S-ribosomal-protein-S15	unknown	unknown	gnl\|CDD\|180170
NC_016785.1\|WP_173664309.1\|1461471_1461765_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223691
NC_016785.1\|WP_014307015.1\|1457714_1458617_+\|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl\|CDD\|235113
NC_016785.1\|WP_014307023.1\|1473802_1474927_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NC_016785.1\|WP_003851923.1\|1465898_1466231_-\|YlxR-family-protein	unknown	unknown	gnl\|CDD\|377288

Protein	Function_ID	Function_description	E-value
NC_016785.1\|WP_003851924.1\|1466486_1467485_-\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	6.55163e-171
NC_016785.1\|WP_010935095.1\|1467481_1468036_-\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	3.05092e-39
NC_016785.1\|WP_014307021.1\|1470863_1471610_+\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	1.18067e-79
NC_016785.1\|WP_014307014.1\|1456720_1457692_-\|bifunctional-riboflavin-kinase/FAD-synthetase	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	2.07665e-141
NC_016785.1\|WP_193350843.1\|1461718_1462303_-\|DHH-family-phosphoesterase	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	3.91847e-31
NC_016785.1\|WP_014302055.1\|1462343_1462787_-\|30S-ribosome-binding-factor-RbfA	gnl\|CDD\|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	3.00142e-41
NC_016785.1\|WP_003851917.1\|1459302_1460109_-\|metallophosphoesterase	gnl\|CDD\|224327	COG1409, Icc, Predicted phosphohydrolases [General function prediction only].	1.03531e-18
NC_016785.1\|WP_010935099.1\|1472452_1473799_+\|YdiU-family-protein	gnl\|CDD\|234583	PRK00029, PRK00029, YdiU family protein.	6.92785e-154
NC_016785.1\|WP_010935090.1\|1458613_1459306_-\|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl\|CDD\|225524	COG2977, EntD, Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism].	2.47862e-55
NC_016785.1\|WP_014307016.1\|1460155_1461475_-\|MATE-family-efflux-transporter	gnl\|CDD\|240541	cd13136, MATE_DinF_like, DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.83007e-95
NC_016785.1\|WP_014307022.1\|1471629_1472454_-\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|381169	cd11642, SUMT, Uroporphyrin-III C-methyltransferase (also known as S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT). SUMT is an enzyme of the cobalamin and siroheme biosynthetic pathway. It catalyzes the first of three steps leading to the formation of siroheme from uroporphyrinogen III; it transfers two methyl groups from S-adenosyl-L-methionine to the C-2 and C-7 atoms of uroporphyrinogen III to yield precorrin-2 via the intermediate formation of precorrin-1. Precorrin-2 is also a precursor for the biosynthesis of vitamin B12, coenzyme F430, siroheme and heme d1. This family includes proteins in which the SUMT domain is fused to other functional domains, such as to a uroporphyrinogen-III synthase domain to form bifunctional uroporphyrinogen-III methylase/uroporphyrinogen-III synthase, or to a dual function dehydrogenase-chelatase domain, as in the case of the multifunctional S-adenosyl-L-methionine (SAM)-dependent bismethyltransferase/dehydrogenase/ferrochelatase CysG, which catalyzes all three steps that transform uroporphyrinogen III into siroheme.	4.33219e-104
NC_016785.1\|WP_010935096.1\|1468087_1468996_+\|DUF4439-domain-containing-protein	gnl\|CDD\|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	2.0974e-08
NC_016785.1\|WP_014307013.1\|1455701_1456661_-\|nucleoside-hydrolase	gnl\|CDD\|239116	cd02650, nuc_hydro_CaPnhB, NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. .	5.92447e-132
NC_016785.1\|WP_014307020.1\|1469074_1470832_-\|proline--tRNA-ligase	gnl\|CDD\|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NC_016785.1\|WP_003851932.1\|1474946_1475456_-\|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl\|CDD\|376440	pfam01035, DNA_binding_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain. This domain is a 3 helical bundle.	4.85709e-35
NC_016785.1\|WP_003851911.1\|1455260_1455530_-\|30S-ribosomal-protein-S15	gnl\|CDD\|180170	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed.	1.46579e-51
NC_016785.1\|WP_173664309.1\|1461471_1461765_-\|hypothetical-protein	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	6.43142e-09
NC_016785.1\|WP_014307015.1\|1457714_1458617_+\|tRNA-pseudouridine(55)-synthase-TruB	gnl\|CDD\|235113	PRK03287, truB, tRNA pseudouridine synthase B; Provisional.	3.07997e-177
NC_016785.1\|WP_014307023.1\|1473802_1474927_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	2.58416e-103
NC_016785.1\|WP_003851923.1\|1465898_1466231_-\|YlxR-family-protein	gnl\|CDD\|377288	pfam04296, DUF448, Protein of unknown function (DUF448).	1.00255e-19

>NC_016785.1|WP_014302055.1|1462343_1462787_-|30S-ribosome-binding-factor-RbfA
MVDHARAARLAKRIQTIVATAIEREVKDRRLEYVTVTDTRVTGDLHDATVYYTVRGRTIDDQPDLKAAAEALQRARGQLRKIVGDQLSVRFTPTLSFELDTVPEASAHMEDLLARARARDLELAELKKNAQPAGDAHPYKDDDAMND
>NC_016785.1|WP_193350843.1|1461718_1462303_-|DHH-family-phosphoesterase
MCVAGHERPDADAVGSVCALVLGLQQAGCHAQGFIGQDAPIGASFMWLPGAHAINLATELPPCDLIITVDYAALSRLGALQKSIVEAKQPVIVLDHHATNHGFGDLNLVDAQAESATSIVYDLCQALGVEITPDIAQCLYSGLVADTGGFRWGRPRIHDLAQTLVEHGADIQQINHNLFDAYSLDDRRPFARCC
>NC_016785.1|WP_173664309.1|1461471_1461765_-|hypothetical-protein
MRIHWMIEGHSRDAVESIADYVRGLYGVDLAVVLKEYSPETWTISLRSDSWDVAAIARKCGGGGHVHAAGMTLHGTEQEIIGSIMAAVAAAAETAKL
>NC_016785.1|WP_014307016.1|1460155_1461475_-|MATE-family-efflux-transporter
MNTSLNDTADRSAHITAVTVLALALPSLGVLAATPLYLLLDTAVVGGLGTVALAALGAGTVIYSQVTTQLTFLSYGTTARSARLYGAGKQGEAVYEGVQATWIALLVGAVLATILFFGAPTFAWWLTGNREVANNAGHWLRITAFGVPMILAIMAGNGWLRGIQNTRAPLVFTLAGVIPGACAVPFFVHWWGLVGSAWANLMGTSITAVLFVGCLARYHRGSWRPQWRIMKTQLVLGRDLILRSFSFQVSFLSAAAVAGRFGAESLAAHQVLMQLWGFLTLVLDSLAIAGQTLTGAALGAGSAAVARAVGEKSIRYSTFFGVVLAAVFTVGWSVIPQVFTRDTNVLNVMAGPWWQLVALIALGGVVFALDGILLGASDAAFLRTVSIASVVCGFLPGVWLALIFDAGLVGVWWGLIAFLCIRLGTCWWRFRSMKWAGVS
>NC_016785.1|WP_003851917.1|1459302_1460109_-|metallophosphoesterase
MVQTLWAVADLHAAVRANGGRIDTIQPHDPSDWLIVAGDVAERTSVVIDVLHELRQRFATVIWVPGNHELFCRSSDRFQGRAKYDELVRRCRQIDVLTPEDPYPVFHGVTVVPLFTLYDYSFRPEGLTIEAALQSAHDKQLVLTDQFAIAPFVDIRAWCWDRLAYSVHRLSRERGPKILINHWPLVQEPVSELPIPEIGLWCGTRHTRSWPVRYSAITVVYGHLHVPNERIIDGVRHVEVSLGYPHQWSQNIEDRSWPFPVMTSEVVA
>NC_016785.1|WP_010935090.1|1458613_1459306_-|4'-phosphopantetheinyl-transferase-superfamily-protein
MIAGNNSEYALDSRLFPQSARSTALLVPRHTPDLSNFNRLHVLEKAQVKNAVAVRRAEFGDARWCAHQSLRKLGLYDHPAILRGERGMPLWPVGIAGSLTHTEGLRAAVVAPTTEVASMGIDAEIAEELPGGILGSIARPNEIAMLDDLRARGLLFADRLLFCAKEATYKAWFPITQRWLDFDQAEIDIRADGTFISYLLIRPTPFPFIEGKWAIHDGYVVATTVIPAMG
>NC_016785.1|WP_014307015.1|1457714_1458617_+|tRNA-pseudouridine(55)-synthase-TruB
MNDALANSGLVIVDKPEGMTSHDVVSKIRRTFSTKKVGHAGTLDPMATGVLVLGLERGTKFLAHMVASTKSYAATIRLGAATTTDDREGETIASASPDQLAAITETKISDAVKQFRGSIMQRPAAVSAIKIDGKRAHQRVREGEKVEIPARPVTISRYDILEIRRDAAFIDIDVEVDCSSGTYIRSLARDLGEELGVGGHLTALRRTQVGPFTLDNAVTLEKLEENPHVSLTLDQALAASYPVLSVSEKEASDLAMGKWLTPRGLKGIHAAVDPHGRAIALVKEQGKRLATIFVARPSTL
>NC_016785.1|WP_014307014.1|1456720_1457692_-|bifunctional-riboflavin-kinase/FAD-synthetase
MDQVDIWHRLEDIPADLKASVITIGVFDGVHRGHRTLVAAATDRAQALGVPSVLVTFNPHPLSVLRPDKMPPLLGTVNQRADLAESLGVDHMFAMNFTAELSHLSPEEFFCSVIKDKLNAQAVVVGKNFTFGYKAAGTTDTLKALGEKYGVEIYVLDLLTENGDVVSSTAIRSDLLEGNIRRANWGLGREFSVHGDVVRGAGRGGKELGFPTANLYFPDSIALPEDGVYAGWLTVTSSAPIDGDMVRGVRYPAAISVGHNPTFGDKRRSVESFVLDRHADLYGHSIVVEFVDRIRPMVKFDGIDELLVAIENDVTQTRAILHI
>NC_016785.1|WP_014307013.1|1455701_1456661_-|nucleoside-hydrolase
MKKIILDLDTGIDDALALAYTLGSPELDLIGVTATYGNVLVETGVRNDLALLELFGRSDVPVFAGEPHALAKDGFEVLEISAFIHGKNGIGEAEVAEPVGVVQELSAVDFLIESVERYGDELIIVPTGAMTNIAAAMKKSETFARDAQIVFMGGALTVPGNVSQWAEANVNQDPEAADIMVRNAGDITMVGLDVTLQTLLTYAETATWRTLGTPAGNFLADATDYYIKAYDTTAPHLGGCGLHDPLAVGVAIDPSLVTLLPINLKVDTEGPTRGRTIGDEVRLNDPHKNCKVAVGVDVDRFLKEFMERITRVAQGSNAR
>NC_016785.1|WP_003851911.1|1455260_1455530_-|30S-ribosomal-protein-S15
MALSTEQKKSILAEYGLHETDTGSPEAQVALLSARINQLTEHLKFHKHDHHSRRGLLLLVGRRKGLLKYLADNNVDRYRDLIARLGLRR
>NC_016785.1|WP_003851923.1|1465898_1466231_-|YlxR-family-protein
MPSDSNQRSQQRIRTCIARRRPLPEASLLRVVALKGPDESAAVRVIPDPQRKMGGRGAWISPTLEALELAEKRRAFNRALRVSAVVDTGHVREYLAGLTARPNIVRKTEH
>NC_016785.1|WP_003851924.1|1466486_1467485_-|transcription-termination/antitermination-protein-NusA
MNIDVQALKAIEADRNIAVDELLETIARALLFAYQEYKDTNTVENSRARVDINSVTGHVSVIVSELDEDGVVTTEYDDTPENFGRVGAQAVRDAIVRRLREAETLKAYDAYSEYEGRVVSGIVQADIFANEKGIVVIHLGTEVDGQDGILIPAEQIPGESFKHGDRVKAYVVGINRTPRDLQINLSRTHPELVRRLFELEVPEVADGSVEIIGIAREAGHRSKVAVKATVKGLNAKGACIGPRGQRVNNIMNELGGEKIDIIDFDDDPAKFVGNALAPSKVVHVEITDAEAQTAQVTVPDYQLSLAIGKEGQNARLAARLTGWKIDIRSDAS
>NC_016785.1|WP_010935095.1|1467481_1468036_-|ribosome-maturation-factor-RimP
MAFPTVEVLTELVTPVVAQHNMDLEGIRINKAGKKSLVAVSVDSDFRPDLDQLELVSNQISEVFDAGEAAGELSFGAGYTLEVGTPGLDQPLASARRWRRNRHRLVALEVEGKKSVERIGALNDDETAVIVVKRRGKKLVVRSVQLAENTQAVVEIEFAKPAEDELALTALEFDQALDRGEENK
>NC_016785.1|WP_010935096.1|1468087_1468996_+|DUF4439-domain-containing-protein
MREVIFLQRSTTSAISAICLLGCVVACDISPSPDPNATLIDLAAIAHNDAAVLQSKNSALAQQRHADSEELISEIQRLCGTNSEGKLPESCSNEIVQGAVDKQAVSLKETVTESDAATRSAQAIVSAIDSAPSESLGLLGQQLVDLVRAGAAAPQSGIAQLNPRNEINKGTSKDDLIHDRESLKKALDWEYSAIYGLGVALAHSPAGTRTAVSDAITAHRDRVELLESSFAESFPNETIPRPEAAYEFSGYPEPHDAQSSRAFFDSLEADSAAWWLHALSESHSATWRALCASLAAQSAARR
>NC_016785.1|WP_014307020.1|1469074_1470832_-|proline--tRNA-ligase
MITRLSTLFLRTLREDPADAEVPSHKLLVRAGYIRRTAPGVYTWLPLGLRTLRKVETVVREEMDAIGAQELLFPALLPREPYEQTHRWTEYGDSLFRLKDRKGGDYLLGPTHEEMFASAVKDMYSSYKDFPVTLYQIQTKYRDEERPRAGILRGREFVMKDSYSFDMSDAGLEDSYQRHREAYQRILDRLGVEYVICAATSGAMGGSASEEFLAVSDNGEDTFVRATEGPYAANVEAVVTQPGVERPLEQAPEAVEYETPHAETIEALVQWAQSAGVTVEDRSVAAADTLKCLLVKITQPGAEEAELAGILLPGDREVDMKRLEASVEPAEVELASEEDFKNKPFLVKGYVGPRALNAHGVKVLADPRVVSGTSWIAGADAVEHHVVGLTMGRDFTVDGYIEAAEIREGDPAPEGQGTLTLARGIEVGHIFQLGRKYTEAFDVQILDESGKRAIPTMGSYGIGVSRLMAVLAEQRHDETGLNWPLEVAPYQVHVVVANKDKEAIEAGDALVAALDSHGIEVLFDDRPKVSPGVKFKDAELLGMPFVVVLGRAFKDGNIELRERGQETVLVSADEIVDTVVAKLNR
>NC_016785.1|WP_014307021.1|1470863_1471610_+|peroxide-stress-protein-YaaA
MLIVLPPSETKAVGGKNPAIDFDSLHFPTLNPIRKEIAHDLARLDISQAQEILKLSQKLLPEAQRNIELFQSPTMPAVLRYTGVLYDALDATSLPSSTWEHLAIGSALFGVVMANDNIPHYRLSGAAKLPCADASVPTLKRRWGNAISTALSDTNEVILDLRSGTYQQLGKVKHAITVRVESEDSDGKRSVISHFNKHYKGQLARALLLHDVTPDPDHVIEDLIGMTQECGFAVEHSKPHELTVVITQ
>NC_016785.1|WP_014307022.1|1471629_1472454_-|uroporphyrinogen-III-C-methyltransferase
MVYRIMKKFTEISSRNRKLFKLAGMFSSSESWTASVSLIGGGPGAWDLITVRGMHRLQQADVILADHLGPASELAQLCDVSTKDIIDVSKLPYGKQVAQSKINELLIEHAQAGKKVARLKGGDPYIFGRGFEELQACAKHGIACEVVPGVTSAVSVPALAGIPITQRGVVHSFTVISGHVPPQHPQSLNDWEALARTGGTLSVIMGVKNAGAIAQALIDAGRGADTPVAVVQEGSTENQKSFKTTLAQLGQAMKDNDIKPPAVYVIGEVAGLQA
>NC_016785.1|WP_010935099.1|1472452_1473799_+|YdiU-family-protein
MPLTFAHSFADAVPSLSVPWRAEQWPDPRIIVFNHELGQELGIDEASLLSNITQQGHAQAYSGHQFGQFNPLLGDGRALVLGDCAQTNAPHGQFEISLKGSGPTPFARRGDGRATLGPMLREYLISEALHGLGIPTTRSLAVITTGTDVQRERLLPGAVVVRVAQNHLRVGSVQCAAMRDDDSLAALVRYALSSHEDGVSDAEAAGLLLRRVSTSQAKLVAQWMRFGFVHGVMNTDNVTLSGQTIDFGPCAFIDSFHPQAVFSSIDSHGRYSFGRQPSIMGWNIARLAEALLPLMSIDEARNIVHEFPDMYRRSWLDEMADAVGISPDDDHAAGVLDDLVALLDVHRPDYAQFMRSLSDGTTVSLFPWAQQWEAEVSSLRVAAPRNPVYVPRNYLVEDALEHAMNADMSVFSLLVEAGKNPYLREKRFEKLENPAPETWQDYVTYCGT
>NC_016785.1|WP_014307023.1|1473802_1474927_-|GTP-binding-protein
MSHSTPVTVLSGFLGSGKTTLLNQMLSNRESKKIAVIVNDFSEINIDAALIAGEGHLERGEDKFVELTNGCICCTLRDDLVQSVGALASSGDYDHIVIESTGISEPMPVAATFEWVWDDGTRLADIAPIDTMATLVDASQFLTYMGKKTYLTDRDLGATEDDERTIADLLVDQVEFADKIYITKSDLVDDERYHATKALVRRMNPRASIDKLVNGRVITASGENRNAINDLLGAMCYDEETARTYQGYVAELDNPHTPETEEYGISSFVFKGDRPFDRQRLIAALRSTRGIVRSKGHCWISDRIDMVQVWHQAGPDLRIAPAGYWQSAGITPSNEIVVIGVNFDHAQAQQLLNDAMLSDSEVQQLLSTADAAKS
>NC_016785.1|WP_003851932.1|1474946_1475456_-|methylated-DNA--[protein]-cysteine-S-methyltransferase
MHAEYGFVSTPDGQFCVVTDSMTHKILASGWTENVSELVGLIHRDLRPLSMREAEVSLSIQNVISAYYDGRFARILTVPLLQQATDFRMSVWSALRRIPSGSPVSYATLARMSGHEGAVRAAASACANNPVALFVPCHRVIRSDGSYGGFRYGLAVKRSLLTREVAHNK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

140991 : 175272

Corynebacterium_phage(93.75%)

capsid,integrase,holin,protease,portal,head

attL 137434:137456|attR 175556:175578

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
137434:137456	attL	NA	NA	NA	NA
WP_014306303.1\|140991_142218_-\|integrase	site-specific integrase	A0A1W6JRD7	Corynebacterium_phage	5.4e-216	90.0
WP_014306304.1\|142317_143340_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_010934088.1\|143351_143915_-	hypothetical protein	NA	NA	NA	NA
WP_010934089.1\|144009_144417_-	ImmA/IrrE family metallo-endopeptidase	A0A1W6JRC2	Corynebacterium_phage	1.7e-73	99.3
WP_014306305.1\|144426_144918_-	hypothetical protein	A0A1W6JRB0	Corynebacterium_phage	3.5e-81	97.5
WP_003850195.1\|145035_145272_+	helix-turn-helix domain-containing protein	A0A1W6JRC7	Corynebacterium_phage	1.2e-34	98.7
WP_041734806.1\|145318_145786_+	hypothetical protein	NA	NA	NA	NA
WP_003850198.1\|146009_146390_-	hypothetical protein	NA	NA	NA	NA
WP_014306307.1\|146577_146847_-	hypothetical protein	NA	NA	NA	NA
WP_003850201.1\|146937_147756_+	phage antirepressor Ant	A0A1W6JRI1	Corynebacterium_phage	9.2e-135	87.5
WP_003850203.1\|147775_147976_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003850204.1\|147972_148215_+	hypothetical protein	A0A1W6JRC8	Corynebacterium_phage	8.4e-20	59.0
WP_003850206.1\|148226_148451_+	hypothetical protein	A0A1W6JRD0	Corynebacterium_phage	4.9e-06	44.4
WP_003850207.1\|148447_148594_+	hypothetical protein	NA	NA	NA	NA
WP_003850214.1\|149009_149711_+	hypothetical protein	NA	NA	NA	NA
WP_014306309.1\|150146_151355_+	hypothetical protein	A0A220NQT1	Corynebacterium_phage	3.6e-135	67.8
WP_014306310.1\|151347_151935_+	hypothetical protein	A0A1W6JRC6	Corynebacterium_phage	7.7e-59	58.9
WP_003850222.1\|152019_152337_+	HNH endonuclease	A0A1W6JRD4	Corynebacterium_phage	1.4e-51	100.0
WP_003850225.1\|152490_152835_+	hypothetical protein	A0A1W6JRH9	Corynebacterium_phage	3.5e-19	50.5
WP_003850227.1\|152824_154426_+	hypothetical protein	A0A1W6JRF6	Corynebacterium_phage	3.6e-159	77.2
WP_014306311.1\|154438_155689_+\|portal	phage portal protein	A0A1W6JRE1	Corynebacterium_phage	9.5e-224	92.8
WP_003850232.1\|155685_156729_+\|head,protease	HK97 family phage prohead protease	A0A1W6JRD9	Corynebacterium_phage	3.4e-182	91.7
WP_014306312.1\|156725_157976_+\|capsid	phage major capsid protein	A0A1W6JRF1	Corynebacterium_phage	5.2e-206	89.4
WP_003850234.1\|157975_158176_+	hypothetical protein	A0A1W6JRE2	Corynebacterium_phage	2.3e-15	65.2
WP_003850235.1\|158197_158680_+	hypothetical protein	A0A1W6JRD8	Corynebacterium_phage	1.6e-83	93.8
WP_010934108.1\|158676_159039_+	hypothetical protein	A0A1W6JRD5	Corynebacterium_phage	3.6e-59	93.3
WP_014306313.1\|159031_159298_+	hypothetical protein	A0A1W6JRE6	Corynebacterium_phage	6.8e-39	94.3
WP_003850238.1\|159287_159665_+	hypothetical protein	A0A1W6JRI9	Corynebacterium_phage	5.8e-60	89.6
WP_014306314.1\|159693_160641_+	hypothetical protein	A0A1W6JRH0	Corynebacterium_phage	7.3e-152	83.8
WP_014306315.1\|160736_161114_+	hypothetical protein	A0A1W6JRK1	Corynebacterium_phage	1.5e-55	89.6
WP_010934113.1\|161275_161485_+	hypothetical protein	A0A1W6JRF2	Corynebacterium_phage	9.1e-31	88.4
WP_014306316.1\|161497_167140_+	hypothetical protein	A0A1W6JRG1	Corynebacterium_phage	0.0e+00	81.9
WP_003850245.1\|167149_167902_+	hypothetical protein	A0A1W6JRF0	Corynebacterium_phage	1.0e-127	88.0
WP_010934115.1\|167902_168763_+	hypothetical protein	Q37921	Corynephage	5.2e-165	99.7
WP_014306319.1\|169876_171073_+	hypothetical protein	A0A1W6JRF8	Corynebacterium_phage	4.0e-46	61.0
WP_014306320.1\|171461_172199_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JRK9	Corynebacterium_phage	3.6e-138	92.2
WP_014306321.1\|172198_172435_+\|holin	holin	A0A1W6JRG0	Corynebacterium_phage	2.5e-29	88.5
WP_014306322.1\|172440_172905_+	hypothetical protein	A0A1W6JRF4	Corynebacterium_phage	1.5e-57	73.5
WP_010934122.1\|172901_173240_+	hypothetical protein	A0A1W6JRH1	Corynebacterium_phage	1.2e-48	88.4
WP_003850266.1\|173589_175272_+	diphtheria toxin	A7UH54	Corynephage	0.0e+00	98.0
175556:175578	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_016785

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection