CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017064	Helicobacter pylori ELS37 plasmid pHPELS37, complete sequence	0 crisprs	cas14j	0	0	0	0
NC_017063	Helicobacter pylori ELS37, complete genome	3 crisprs	c2c9_V-U4,cas14j,cas3,DEDDh	0	3	2	0

1. NC_017063

CRISPR-Cas detection and classification

Crispr_ID: NC_017063_1

• CRISPR_ID: NC_017063_1
• CRISPR_location: 381614-381812
• CRISPR_type: Orphan
• Repeat_type: I-B
• Spacer_info: 3 spacers

Consensus repeat of NC_017063_1

Consensus_repeat	Method
TATTAAAGTTATAAGTCCCTTGATTGAA	CRT

spacers of NC_017063_1

>1.1|381642|26|NC_017063|CRT
GGTGTCGTTATTAAAGCTAACATTGT
>1.2|381696|29|NC_017063|CRT
AGCACTGTTATTAAAAGCAGATTGGACGC
>1.3|381753|32|NC_017063|CRT
ACTACTATTATCAAAGCTTGAACTTGCGCTGT

CRISPR arrays and Neighbor proteins around NC_017063_1

CRISPR arrays

The CRISPR arrays of NC_017063_1

>merge|NC_017063|1|381614-381812|CRT
TATTAAAGCTATAAGTCCCTTGATTGAAGGTGTCGTTATTAAAGCTAACATTGTCATTAAAATTATAAGTCCCTTGATTGAAAGCACTGTTATTAAAAGCAGATTGGACGCTATTAAAGTTGTAAGTCCCTTGATTGAAACTACTATTATCAAAGCTTGAACTTGCGCTGTTACTAAAGTGATAAGTGCCTTGATTGAA

>NC_017063|1|1|381614-381812|CRT
TATTAAAGCTATAAGTCCCTTGATTGAA	GGTGTCGTTATTAAAGCTAACATTGT
CATTAAAATTATAAGTCCCTTGATTGAA	AGCACTGTTATTAAAAGCAGATTGGACGC
TATTAAAGTTGTAAGTCCCTTGATTGAA	ACTACTATTATCAAAGCTTGAACTTGCGCTGT
TACTAAAGTGATAAGTGCCTTGATTGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017063.1|WP_001115881.1|373954_374161_+|4-oxalocrotonate-tautomerase-family-protein	unknown	unknown	gnl|CDD|129125
NC_017063.1|WP_001240210.1|383818_384511_+|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl|CDD|198414
NC_017063.1|WP_014419516.1|391252_392797_+|outer-membrane-beta-barrel-protein-HofG	unknown	unknown	gnl|CDD|334957
NC_017063.1|WP_000812578.1|393360_394941_-|Hop-family-adhesin-AlpB	unknown	unknown	gnl|CDD|280099
NC_017063.1|WP_000894580.1|397353_399381_-|ATP-dependent-helicase	unknown	unknown	gnl|CDD|223288
NC_017063.1|WP_000236810.1|367636_368239_-|6-pyruvoyl-tetrahydropterin-synthase-family-protein	unknown	unknown	gnl|CDD|223792
NC_017063.1|WP_000998420.1|388476_390924_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|224544
NC_017063.1|WP_000426968.1|370622_371165_-|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl|CDD|129173
NC_017063.1|WP_000775569.1|366877_367633_-|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl|CDD|223675
NC_017063.1|WP_080012231.1|399374_400523_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|223897
NC_017063.1|WP_000592406.1|394962_396501_-|Hop-family-adhesin-AlpA	unknown	unknown	gnl|CDD|280099
NC_017063.1|WP_080012186.1|371165_372146_-|zinc-metalloprotease-HtpX	unknown	unknown	gnl|CDD|235081
NC_017063.1|WP_001160286.1|374228_375338_-|Hop-family-outer-membrane-protein-HopJ/HopK	unknown	unknown	gnl|CDD|280099
NC_017063.1|WP_000722498.1|368895_369699_-|5'/3'-nucleotidase-SurE	unknown	unknown	gnl|CDD|234732
NC_017063.1|WP_014419518.1|400544_401132_-|hypothetical-protein	unknown	unknown	unknown
NC_017063.1|WP_001087917.1|369695_370607_-|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|223220
NC_017063.1|WP_000688674.1|382675_383674_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|273675
NC_017063.1|WP_001052423.1|372084_373230_-|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl|CDD|272903
NC_017063.1|WP_001230014.1|387871_388303_+|hypothetical-protein	unknown	unknown	gnl|CDD|376519
NC_017063.1|WP_001099624.1|373226_373808_-|recombination-protein-RecR	unknown	unknown	gnl|CDD|273176

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017063.1|WP_001115881.1|373954_374161_+|4-oxalocrotonate-tautomerase-family-protein	gnl|CDD|129125	TIGR00013, Probable_tautomerase_K2, 4-oxalocrotonate tautomerase family enzyme. 4-oxalocrotonate tautomerase is a homohexamer in which each monomer is very small, at about 62 amino acids. Pro-1 of the mature protein serves as a general base. The enzyme functions in meta-cleavage pathways of aromatic hydrocarbon catabolism. Because several Arg residues located near the active site in the crystal structure of Pseudomonas putida are not conserved among all members of this family, because the literature describes a general role in the isomerization of beta,gamma-unsaturated enones to their alpha,beta-isomers, and because of the presence of fairly distantly related paralogs in Campylobacter jejuni, the family is regarded as not necessarily uniform in function. [Energy metabolism, Other].	2.46126e-26
NC_017063.1|WP_001240210.1|383818_384511_+|Bax-inhibitor-1/YccA-family-protein	gnl|CDD|198414	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins. This family is comprised of bacterial relatives of the mammalian members of the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. In plants, BI-1 like proteins play a role in pathogen resistance. A characterized prokaryotic member, Escherichia coli YccA, has been shown to interact with ATP-dependent protease FtsH, which degrades abnormal membrane proteins as part of a quality control mechanism to keep the integrity of biological membranes.	2.16314e-52
NC_017063.1|WP_014419516.1|391252_392797_+|outer-membrane-beta-barrel-protein-HofG	gnl|CDD|334957	pfam02521, HP_OMP_2, Putative outer membrane protein. This family consists of putative outer membrane proteins from Helicobacter pylori (campylobacter pylori).	4.05757e-178
NC_017063.1|WP_000812578.1|393360_394941_-|Hop-family-adhesin-AlpB	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	1.27635e-53
NC_017063.1|WP_000894580.1|397353_399381_-|ATP-dependent-helicase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	1.36747e-134
NC_017063.1|WP_000236810.1|367636_368239_-|6-pyruvoyl-tetrahydropterin-synthase-family-protein	gnl|CDD|223792	COG0720, COG0720, 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism].	2.12511e-20
NC_017063.1|WP_000998420.1|388476_390924_+|TonB-dependent-receptor	gnl|CDD|224544	COG1629, CirA, Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism].	3.96835e-35
NC_017063.1|WP_000426968.1|370622_371165_-|GTP-cyclohydrolase-I-FolE	gnl|CDD|129173	TIGR00063, GTP_cyclohydrolase_1, GTP cyclohydrolase I. alternate names: Punch (Drosophila),GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate in prokaryotes, of tetrahydrobiopterin in vertebrates, and of pteridine-containing pigments in insects. [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	8.93751e-107
NC_017063.1|WP_000775569.1|366877_367633_-|7-carboxy-7-deazaguanine-synthase-QueE	gnl|CDD|223675	COG0602, NrdG, Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones].	4.69089e-47
NC_017063.1|WP_080012231.1|399374_400523_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	3.31897e-52
NC_017063.1|WP_000592406.1|394962_396501_-|Hop-family-adhesin-AlpA	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	7.66768e-54
NC_017063.1|WP_080012186.1|371165_372146_-|zinc-metalloprotease-HtpX	gnl|CDD|235081	PRK02870, PRK02870, heat shock protein HtpX; Provisional.	0
NC_017063.1|WP_001160286.1|374228_375338_-|Hop-family-outer-membrane-protein-HopJ/HopK	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	1.14427e-47
NC_017063.1|WP_000722498.1|368895_369699_-|5'/3'-nucleotidase-SurE	gnl|CDD|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	9.63853e-126
NC_017063.1|WP_001087917.1|369695_370607_-|polyprenyl-synthetase-family-protein	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	4.39419e-76
NC_017063.1|WP_000688674.1|382675_383674_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	7.90812e-157
NC_017063.1|WP_001052423.1|372084_373230_-|tRNA-pseudouridine(13)-synthase-TruD	gnl|CDD|272903	TIGR00094, tRNA_pseudouridine_synthase_D, tRNA pseudouridine synthase, TruD family. an EGAD loading error caused one member to be called surE, but that's an adjacent gene. MJ11364 is a strong partial match from 50 to 230 aa. [Protein synthesis, tRNA and rRNA base modification].	5.53659e-143
NC_017063.1|WP_001230014.1|387871_388303_+|hypothetical-protein	gnl|CDD|376519	pfam01300, Sua5_yciO_yrdC, Telomere recombination. This domain has been shown to bind preferentially to dsRNA. The domain is found in SUA5 as well as HypF and YrdC. It has also been shown to be required for telomere recombniation in yeast.	0.000258345
NC_017063.1|WP_001099624.1|373226_373808_-|recombination-protein-RecR	gnl|CDD|273176	TIGR00615, Recombination_protein_RecR, recombination protein RecR. All proteins in this family for which functions are known are involved in the initiation of recombination and recombinational repair. RecF is also required. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	9.68647e-98

Protein sequences

>NC_017063.1|WP_001160286.1|374228_375338_-|Hop-family-outer-membrane-protein-HopJ/HopK
MQFPKALLHSSFFLPLFLSCCIAEENGAYASVGFEYSISHAVEHNNPFLNQERIQIISNAQNKIYKLNQVENEIKGMPNTFNYINNALKNHAKLTPTEMQAEQYYLQSTLQNIEKIVTLSGGIASNPKLAQALEKMQEPITNPLEFEENLKNLELQFNQSQNNMLSSLSSQIAQISNSLNALDPTSYSKNISSMYGVSLSVGYKHFFTKKKNQGFRYYLFYDYGYTNFGFVGNGFDGLGKMNNHLYGLGIDYLFNFIDNAKKHSSVGFYIGFALAGSSWVGSGLGMWVSQTDFINNYLTNYQSKMHTSFFQIPLNFGVRVNVDRHNGFEMGLKIPLAVNSFYETHGKGLNTSLFFKRLVVFNVSYVYSF
>NC_017063.1|WP_001115881.1|373954_374161_+|4-oxalocrotonate-tautomerase-family-protein
MPFINIKLVPENGGPTNEQKQQLIEGVSDLMVKVLNKNKASIVVIIDEVDSNNYGLGGESVHHLRQKN
>NC_017063.1|WP_001099624.1|373226_373808_-|recombination-protein-RecR
MNTYKNSLNHFLNLVDCLEKIPNVGKKSAFKMAYHLGLENPYLALKITHALENALENLKTCTSCNALSESEVCEICSDESRQNSQLCMVLHPRDVFILEDLKDFLGRYYVLNSIEEVDFNALEKRLIEENIKEIIFAFPPTLANDSLMLYIEDKLQHFHLTFTKIAQGVPTGVNFENIDSVSLSRAFNSRIKA
>NC_017063.1|WP_001052423.1|372084_373230_-|tRNA-pseudouridine(13)-synthase-TruD
MNLNFMPLLHAYNHASIDFHFNSSARDFCVHEVPLYEFSNTGEHAVIQVRKSGLSTLEMLQVFSQILGVKIAELGYAGLKDKNALTTQFISLPKKYAPLLEKNTSNFQERNLKILSLNYHHNKIKLGHLKGNRFFMRFKKMTPLNAQKTKQVLEQIAQFGMPNYFGSQRFGKFNDNHQEGLKILQNQTKFAHQKLNAFLISSYQSYLFNSLLSKRLEISKIISDFSVKENLEFFKQKNLSVDSNTLKALKNQAHPFKILEGDVMCHYPYGKFFDALELEKEGERFLKKEAVPTGLLDGKKALYAKNLSLEIEKEFQHNLLNSHAKTLGSRRFFWVFAENVTSQYIKEKAQFELGFYLPKGSYASALLKEIKHEKGENNDEF
>NC_017063.1|WP_080012186.1|371165_372146_-|zinc-metalloprotease-HtpX
MRARYSKKSSMRKEKIMTNFEKIIAQNRLKTNAVLATYCTIFAFIGLLVDAIRINANDLGIALFKLMTFQIFPTITMIMFLVAFVIIVVCIQNFSSIMLSGDEYKLIDPSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDEANSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLLLQIILPFLTLILQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYTNNDYKEIDKNSTRSAAYLFNAEMFSTHPSVKNRIQSLRKCVI
>NC_017063.1|WP_000426968.1|370622_371165_-|GTP-cyclohydrolase-I-FolE
MENFFNQFFENIGEDKNREGLKETPKRVQELWKFLYKGYKEDPRVALKSAYFQGVCDEMIVAQNIEFYSTCEHHLLPFFGNISVGYIPKEKIVGISAIAKLIEIYSKRLQIQERLTTQIAETFDEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDPKTRAEFMQLLKS
>NC_017063.1|WP_001087917.1|369695_370607_-|polyprenyl-synthetase-family-protein
MNSPNLSFYCNECERFESFLKNHHLHLEGFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCALVGQKDYPSQQTEYFKIALSIECLHTYSLIHDDLPCMDNAALRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNALLESRIIVELVKILSANGGIKGMILGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLIMGLVASGINDEELLKWLQAFGLKMGLCFQVLDDIIDVTQDEEESGKTTHLDSAKNSFVNLLGLEKASGYAQTLKTEVLNDLNALEPTYPLLQENLNALLNTLFKGKT
>NC_017063.1|WP_000722498.1|368895_369699_-|5'/3'-nucleotidase-SurE
MKKILLTNDDGYHAKGIKALEQALENMAEIYVVAPKHEKSACSQCITITAPLRAEKIKGKEGRHYRIDDGTPSDCVYLAINELFKHVCFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFKNGYPLKGRKLLNVNVPNCSLQEYKGERITPKGYRLYKKEVHKRTDPKNESYFWLGLHPLEWQKRENEDRLSDFDAIASNHASITPLNLDLTSYDDLKSLESWHEGMLK
>NC_017063.1|WP_000236810.1|367636_368239_-|6-pyruvoyl-tetrahydropterin-synthase-family-protein
MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDSANMALDFGLMQQEMQTFIDSFDHAHHFWDKESLEFQRFIENHCVRYVKCSFNLSAESYALMFLYYLTRILQKSVFSNNEGELKVSSVRVHETKNGYAESFLKDLENPHFKSLVHDHCVSFSQGIQNLWHDKDFFNKIISDEEKCFFHAKPLHQIP
>NC_017063.1|WP_000775569.1|366877_367633_-|7-carboxy-7-deazaguanine-synthase-QueE
MKLPVVESFFSLQGEGKNIGKPSLFLRLGGCNLSCKGFNCKTILHDEILTGCDSLYAVHPKFKETWDYYNEPESLIERLVNLAPNYKHFDFILTGGEPSLYFNNPILISVLEHFYRQKIPLCVESNGSIFFEFSPILKELHFTLSVKLSFSLEEESKRINLKALQNILNNAKSVHFKFVLESQNAAQSIIEIQSLLKQLSLKNNEIFLMPLGTNNNELDKNLKTLAPLAIKHGFRLSDRLHIRLWDNKKGF
>NC_017063.1|WP_000688674.1|382675_383674_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MKIFINGFGRIGRCVLRAVLERSDTNPKLEVIGINDPANWEILAYLLEHDSTHGLLNKEAHYSNHKLIIGSLEIPVFNSIKDLKGVDVILECSGKFLEPKTLENYLLLGAKKVLLSAPFMGEYDEKQYPTLVYGVNHFLYQNQAIVSNASCTTNAIAPICAILDKAFNIKEGMLTTIHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSMIDLSLFLEKKALKDPINDLLIEASKGVLKGVLEIDLKERVSSDFISNPSSVIIAPDLTFTLENMVKIMGWYDNEWGYSNRLVDMAQFMYHY
>NC_017063.1|WP_001240210.1|383818_384511_+|Bax-inhibitor-1/YccA-family-protein
MALYDRADSHNAYAEDSVLHESELVGFVKTTYKFFAGSLLLATIGALLGLMNFQAVVQYKWVFFIAEIAAFFGLMFSKSKPGLNLFMLFAFTSLSGVTLVPLLGMVIAKAGLGVVWQALGMTTIVFGLMSVYALKTKNDLANMGKMLFIALIVVVVCSLINLFLGSPMFQVVIAGASAILFSLYIAYDTQNIVKGMYDSPIDAAVDLYLDFLNVFISILQIIGIFSDRDK
>NC_017063.1|WP_001230014.1|387871_388303_+|hypothetical-protein
MALVYLVQSDTTIGLLSKDSEKLNALKKRPKNQSVLIESADFTTLKSLVRAPNAFKNLIRRSAKTTFIYPNSKAVRVIRGRHGDFLKRFKTLYSTSANLTQCAYDKEIASNLADVIVSDERGLFESSSSKIFRLYKDKKVRVR
>NC_017063.1|WP_000998420.1|388476_390924_+|TonB-dependent-receptor
MNDKRFRKYCSFSIFLSLLGMFELEAKEEEKEERKTERKKDKKKNAQHTLGKVTTQAAKIFNYNNQTTISSKELERRQANQISDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGAAQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALIGAIKMETRSASDFIPKGKDYAISGAATFLTNFGDRETVMGAYRNHHFDMLLYYTHQNIFYYRDGDNAMKNLFDPKADNKVTGSPSEQNNVMAKINGYLSERDTLTLSYNMTRDNANRPLRANFTGTFLPYSCGDFNAFPNDQNPDDCLFENDASLFKTYSVNLVHNVSLNYEREGGSRFGDPKLKINGYTSIRNVQIDPLFKPSDIAAIIPFTPNPQLSQGEENQCVAQGGIYDATKQTCSITFKSLGGGSVVANKNLFIINSGFNANVIHTIDHKNDNLLEYGLNYQNLTTFDKAIPNSELVKPGDAPDACLRVMGPNDPNMNGRCQRNGATANVVGVYAQANYTLHPMVTLGAGTRYDVYTLVDKDWQLHITQGFSPSAALNVSPLENLNFRLSYAYVTRGPMPGGLVWMRQDNLRYNRNLKPEIGQNVEFNTEYSSQYFDFRAAGFVQLISNYINQFSSTLFVTNLPAQDIIYVPGYEVSGTAKYKGFSLGLSVARSWPSLKGRLIADVYELAATTGNVFILTASYTIPRTGLSITWLSRFVTDLSYCSYSPYRNGPTDIDRRPSNCPKTPGIFHVHKPGYGVSSFFITYKPTYKKLKGLSLNAVFNNVFNQQYINQASPVMSPDEPNQDKYARGMAEPGFNARFEISYKF
>NC_017063.1|WP_014419516.1|391252_392797_+|outer-membrane-beta-barrel-protein-HofG
MKQEKYFLTSSLSLLSFLLCPVEAFDYRFSGRVENFSKIGFNNSQLNTKKGIYPTESFIDIVTLAQVKVNLLPKGTENHRLSVSLGGAIAAIPYDKTKYDINQANGKVFGSIVENFIGGYHGYFFNKYLGPAYAGTSQSASYHARPYVVDTAFLRYDYKDVFGFKAGRYEANIDFMSGSNQGWEVYYQPYKTETQRLRFWWWSSFGRGLAFNSWIYEFFATVPYLKKGGNPSNSNDFINYGWHGITTTYSYKGLDAQFFYYFAPKTYNAPGFKLVYDTNRNFENVGFRSQSMIMTTFPLYYRGWYNPETNTYSLEDSTPHGSLLGRNGVTLNIRQVFWWDIFNWSIGFYNTFGNSDAFLGSHTMPRGNNTSYISNEISVTTRHAGMIGYDFWDNTAYDGLADAITNANTFTFYTSVGGIHKRFAWHVFGRVSHANKNALGQVGRANEYSLQFNASYAFTESILLNFRITYYGARINKGYQAGYFGAPKFNNPDGDFSANYQDRSYMMTNLTLKF
>NC_017063.1|WP_000812578.1|393360_394941_-|Hop-family-adhesin-AlpB
MKQNLKPFKMIKENLMTQSQKVRFLAPLSLALSLSFNPVGAEEDGGFMTFGYELGQVVQQVKNPGKIKAEELAGLLNSTTTNNTNINIAGTGGNVAGTLGNLFMNQLGNLIDLYPTLNTSSIHQCGSTSTSGTTAAATTSNSPCFQGNLSLYNEMVSSIKTLSQDLKNNIFQGNNNTTSANLSNQLSELNTASVYLTYMNSFLNANNQAGGIFQNNTNQAYGNGVTAQQIAYVLKQASITMGPSGNGGAAGAFLDAALAQHVFNSANAGNDLSAKEFTSLVQNIVNTSQNALTLANNANISNSTGYQVSYGGNIDQARSTQLLNNTTNTLAKVSALNNELKANPWLGNFAAGNSSQVNAFNGFITKIGYKQFFGENKNVGLRYYGFFSYNGAGVGNGPTYNQVNLLTYGVGTDVLYNVFSRSFGSRSLNAGFFGGIQLAGDTYISTLRNSPQLASRPTATKFQFLFDVGLRMNFGILKKDLKSHNQHSIEIGVQIPTIYNTYYKAGGAEVKYFRPYSVYWVYGYAF
>NC_017063.1|WP_000592406.1|394962_396501_-|Hop-family-adhesin-AlpA
MIKKNRTLFLSLALCASISYAEDDGGFFTVGYQLGQVMQDVQNPGGAKSDELARELNADVTNNILNNNTGGNVAGALSNAFSQYLYSLLGAYPEKLNGNDVSANALLGGAVGSGTCAAAGTAGGNSLNTQSACTAAGYYWLPSLSDRVLSTIGSQTNYGTNTNFPNMQQQLTYLNAANVFFNAMNKALEAKNGTSSATGQNGQTYSQSAIAYLQGQQNILNNAANLLKQDELLLEAFNSAVAANIGNKEFNSAVFTGLVQGIIDQSQLVYNELSKNPISGSAVNSAGINSNQANAVQGRASQLPNALYNAQVTLDKINALNNQVRSMPYLPQFRAGNSRATNILNGFYTKIGYKQFFGKKRNIGLRYYGFFSYNGASVGFRSTQNNVGLYTYGVGTDVLYNIFSRSYQNRSVDMGFFSGIQLAGETVQSTLRDDPNVKLHGKINNTHFQFLFDFGMRMNFGKLDGKSNRHNQHTVEFGVVVPTIYNTYYKSAGTTVKYFRPYSVYWSYGYSF
>NC_017063.1|WP_000894580.1|397353_399381_-|ATP-dependent-helicase
MLETLQLNPEQLKAAKALQGYNLVIASAGTGKTSTIVGRILYLLDNGIKPEEILLLTFTNKASNEMIARVAKYFKLSSKIEAGTFHAVAYRYLKEHYPNLSLKQPKELRKLLESIVDTKNAIDDDKKPYTSQHLYALYSLYTNALKQEDFSTWLSTKNPEHAPYAALYENILEEFENTKKKHNYIDYNDLLLLFKQAMLERPSPYKEVLCDEFQDTNPLQESILDAINPPSLFCVGDYDQSIYAFNGADISIISNFTQKYKNAQVFTLTKNYRSSKEILDLANQVIQHNERIYPKNLEVVKSGHFNKPALLNYNDNIAQCQDIAKRIVMRKNFKEVAVIFRNNASADQLEAALRSHNVPSKRKGSASFFESKEVALALDICTLIFNSKDIMAAIHVLSHISDIGSNTAKDIHEALMLLGNGDLKLALTHPNKEAKIYTKKKEITSMGLFEEIFALENSSRFNSVIDKAFHSHPVLMHPKISLNGAKMLSDFFILYTKAPIHSPSALIKHILESAFFQTFKTRLLKERSKNKDGSYNEFKKLQAQKRFNEKMDLLSSLAKNYQNLGRFLNGTLIGSSEATQGEGVNLLSVHASKGLEFKDVYIIDLMEGRFPNHKLMNTGGGIEEERRLFYVAITRAKENLWLSYAKNELRENVKPKEHKPSVFLYEAGLLKPNSK
>NC_017063.1|WP_080012231.1|399374_400523_-|class-I-SAM-dependent-methyltransferase
MNNLDIKTLGQVFTPKNIVDFMLTLKHNQGSVLEPSAGDGSFLERLKKAVGIEIDPKICPKNALCMDFFDYPLENQFDTIIGNPPYVKHKDIAPSTKEKLHYSFFDERSNLYLFFIEKAIKHLKPKGELIFITPRDFLKSTSSVKLNEWIYKEGTITHFFELGDQKIFPNAMPNCVIFRFCKGDFSRIANDGLQFVCKKGILYFLNQSYTQKLSEVFKVKVGAVSGCDKIFKNETYGNLEFVTSITKRTNVLEKMVFVNEPNDYLLQHKDSLMQRKIKKFNENNWFEWGRMHHISPKKRIYVNAKTRQKNPFFIHQCPNYDGSILALFPYNQHLDLQNLCDKLNAINWQELGFVCDGRFLFSQRSLENALLPKDFLDESKTC
>NC_017063.1|WP_014419518.1|400544_401132_-|hypothetical-protein
MIPTQLNETAEFLKTNPYHLSQPLQDGRLNPSVNEKEILNTIKHSFPIQLPKAREWWDFSFKKNDIFYPVNIKTTTTKTADNLNCKLGIYYALCGLVPEFNNEIAWEKYFQKLHKDLGKNTDRDYYFLIINKNDPKDIFINSLKGIQTLQPNGNNLPFQCKWDNNREIVQRDFIESKNFILSALAKSVKLRANIY

Crispr_ID: NC_017063_2

• CRISPR_ID: NC_017063_2
• CRISPR_location: 719092-719238
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017063_2

Consensus_repeat	Method
GTTGAAATTAAACGAACCGCCATTAAA	CRISPRCasFinder

spacers of NC_017063_2

>2.1|719119|30|NC_017063|CRISPRCasFinder
AACATTCCCATTAAAATCCACTTGCTTGGC
>2.2|719176|36|NC_017063|CRISPRCasFinder
CGAGTTGTTATTAAAAGCGTTTGTCTGCTCTGCATG

CRISPR arrays and Neighbor proteins around NC_017063_2

CRISPR arrays

The CRISPR arrays of NC_017063_2

>merge|NC_017063|2|719092-719238|CRISPRCasFinder
ATTGAAATTAAACACGCCCCCATTAAAAACATTCCCATTAAAATCCACTTGCTTGGCGTTGAAATTAAACGAACCGCCATTAAACGAGTTGTTATTAAAAGCGTTTGTCTGCTCTGCATGGTTGAAATTAAACGAACCGCCATTAAA

>NC_017063|2|1|719092-719238|CRISPRCasFinder
ATTGAAATTAAACACGCCCCCATTAAA	AACATTCCCATTAAAATCCACTTGCTTGGC
GTTGAAATTAAACGAACCGCCATTAAA	CGAGTTGTTATTAAAAGCGTTTGTCTGCTCTGCATG
GTTGAAATTAAACGAACCGCCATTAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017063.1|WP_000467805.1|733366_734668_+|hemolysin	unknown	unknown	gnl|CDD|206779
NC_017063.1|WP_000251163.1|706552_707494_-|chemotaxis-protein-CheV	unknown	unknown	gnl|CDD|223905
NC_017063.1|WP_000580698.1|703169_704168_-|glycosyltransferase-family-25-protein	unknown	unknown	gnl|CDD|225843
NC_017063.1|WP_000619654.1|725187_725892_-|efflux-RND-transporter-periplasmic-adaptor-subunit-HefB	unknown	unknown	gnl|CDD|273776
NC_017063.1|WP_000724680.1|721528_722098_-|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|280099
NC_017063.1|WP_049792137.1|710345_710993_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224054
NC_017063.1|WP_001064007.1|698746_700990_+|endonuclease-MutS2	unknown	unknown	gnl|CDD|234750
NC_017063.1|WP_080012239.1|728432_729002_-|hypothetical-protein	unknown	unknown	unknown
NC_017063.1|WP_001256455.1|704784_706518_-|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775
NC_017063.1|WP_000972529.1|727344_728367_-|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
NC_017063.1|WP_000887256.1|729046_729703_-|3-methyladenine-DNA-glycosylase	unknown	unknown	gnl|CDD|184390
NC_017063.1|WP_000885496.1|729820_731353_-|flagellin-A	unknown	unknown	gnl|CDD|237146
NC_017063.1|WP_000278401.1|722094_725175_-|efflux-RND-transporter-permease-subunit-HefC	unknown	unknown	gnl|CDD|334294
NC_017063.1|WP_000500917.1|710992_711748_+|ABC-transporter-permease	unknown	unknown	unknown
NC_017063.1|WP_001092149.1|725902_727336_-|efflux-RND-transporter-outer-membrane-subunit-HefA	unknown	unknown	gnl|CDD|224455
NC_017063.1|WP_000969960.1|709664_710000_+|hypothetical-protein	unknown	unknown	unknown
NC_017063.1|WP_001046997.1|701143_701665_-|inorganic-diphosphatase	unknown	unknown	gnl|CDD|179262
NC_017063.1|WP_000811286.1|704192_704768_-|adenylate-kinase	unknown	unknown	gnl|CDD|234711
NC_017063.1|WP_001194402.1|731516_732413_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NC_017063.1|WP_000597661.1|707571_709542_+|DNA-ligase-(NAD(+))-LigA	unknown	unknown	gnl|CDD|236137

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017063.1|WP_000467805.1|733366_734668_+|hemolysin	gnl|CDD|206779	cd11386, MCP_signal, Methyl-accepting chemotaxis protein (MCP), signaling domain. Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.	2.00931e-43
NC_017063.1|WP_001256455.1|704784_706518_-|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NC_017063.1|WP_000580698.1|703169_704168_-|glycosyltransferase-family-25-protein	gnl|CDD|225843	COG3306, COG3306, Glycosyltransferase involved in LPS biosynthesis [Cell envelope biogenesis, outer membrane].	2.76196e-67
NC_017063.1|WP_000724680.1|721528_722098_-|outer-membrane-beta-barrel-protein	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	5.20532e-08
NC_017063.1|WP_049792137.1|710345_710993_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.30588e-39
NC_017063.1|WP_000251163.1|706552_707494_-|chemotaxis-protein-CheV	gnl|CDD|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	2.4954e-33
NC_017063.1|WP_001046997.1|701143_701665_-|inorganic-diphosphatase	gnl|CDD|179262	PRK01250, PRK01250, inorganic diphosphatase.	8.30763e-95
NC_017063.1|WP_000885496.1|729820_731353_-|flagellin-A	gnl|CDD|237146	PRK12584, PRK12584, flagellin A; Reviewed.	0
NC_017063.1|WP_000278401.1|722094_725175_-|efflux-RND-transporter-permease-subunit-HefC	gnl|CDD|334294	pfam00873, ACR_tran, AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.	0
NC_017063.1|WP_000619654.1|725187_725892_-|efflux-RND-transporter-periplasmic-adaptor-subunit-HefB	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	8.71081e-24
NC_017063.1|WP_001092149.1|725902_727336_-|efflux-RND-transporter-outer-membrane-subunit-HefA	gnl|CDD|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	3.7387e-31
NC_017063.1|WP_000972529.1|727344_728367_-|uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NC_017063.1|WP_001064007.1|698746_700990_+|endonuclease-MutS2	gnl|CDD|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0
NC_017063.1|WP_000811286.1|704192_704768_-|adenylate-kinase	gnl|CDD|234711	PRK00279, adk, adenylate kinase; Reviewed.	1.28471e-64
NC_017063.1|WP_001194402.1|731516_732413_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.10558e-17
NC_017063.1|WP_000887256.1|729046_729703_-|3-methyladenine-DNA-glycosylase	gnl|CDD|184390	PRK13913, PRK13913, 3-methyladenine DNA glycosylase; Provisional.	1.28473e-132
NC_017063.1|WP_000597661.1|707571_709542_+|DNA-ligase-(NAD(+))-LigA	gnl|CDD|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0

Protein sequences

>NC_017063.1|WP_000500917.1|710992_711748_+|ABC-transporter-permease
MGAILSILKLEIKSYLTNTSALFWTFIYPILMLLLLIFVFSKNTTEIFYFNNIIGLMGLLIISSAIFGLTQAITSSRSHNIFLFYMLSPATFKQITLALIASRLIVVILYAFIFIVLSFYALNIITILNFKALILGFVSVFSSALFCFCLAIFVARIFQNEQSILGFCNIINLYALMSCNVFVPLEYLPNIGQLFIKTSIFYYLNQLLIKAFQGIDTILVLATSTFFIIGGIILFLLSANRMLLTPKERMR
>NC_017063.1|WP_049792137.1|710345_710993_+|ABC-transporter-ATP-binding-protein
MQDFSFKSHTSTAIIGTNGAGKSTLINTILGIRSDYNFKAQNNNIPYHDNVIPQRKQLGVVSNLFNYPPGLNANDLFKFYQFFHKNCTPNLFEKNLLNKTYEHLSDGQKQRLKIDLALSHHPQLIIMDEPETSLEQNALIRLSNLISLRNTQQLTSIIATHDPIVLDSCEWVLFLKNGNIAKYKRLNSILKSVAKTFNLKEKLTTKDLLALLKDI
>NC_017063.1|WP_000969960.1|709664_710000_+|hypothetical-protein
MMEHHKVHTTVQALQAKRKRLLTELAELEAEIKVSSERRSSFNISLSPSLLAEIEEIEYEEKTSKERRINHSVLLSPSFMAKVDEYMKEKGFPNRSLLFEKALEFYMLKHP
>NC_017063.1|WP_000597661.1|707571_709542_+|DNA-ligase-(NAD(+))-LigA
MIKSQKEYLERIEYLNTLSHHYYNLDESIVSDAVYDELYQELKAYEEENPNDIQANSPTQKVGATATNEFSKNPHLMRMWSLDDVFNQSELQAWLQRILKVYPNASFVCSPKLDGVSLNLLYQHGKLVKATTRGNGLEGELVTHNAKHIANIPHAIAYNGEIEIRGEVIISKKDFDALNKERLNANEPLFANPRNAASGSLRQLDSEITKKRKLQFVPWGVGKHSLNFLSFKECLDFIVSLGFSTIQYLSLNKNHQEIEENYHTLIREREGFFALLDGMVIVVDELDIQKELGYTQKSPKFACAYKFPALEKHTKIIGVINQVGRSGAITPVAVLEPIEIAGAMVTKATLHNYSEIEKKNIMLNDRVVVIRSGDVIPKIIKPLESYRDGSQHKIERPKVCPICSHELLCEEIFTYCQNLNCPARLKESLIHFASKDALNIQGLGDKVIEQLFEEKLIVNALDLYALKLEDLMRLDKFKIKKAQNLLDAILKSKNPPLWRLINALGIEHIGKGASKTLAKYGLNVLEKSEAEFLEMEGFGVEMARSLVNFYASNQEFIRSLFDLLNPKNSDMAEEKQESSSVFNNKTIVLTGTLSKPRQEYAQMLENLGAKIASSVSVKTDFLIVGENPGSKLALAKKHGVSVLNEEELLKRLKELD
>NC_017063.1|WP_000251163.1|706552_707494_-|chemotaxis-protein-CheV
MVRDIDKTTSLHLNNEAQFLCFRLDAEKDAQLYGMNIFKIREIIHYDGEVTEILGGSDGVMLGFLSVRGESIPLVDVKRWLHYNANDPSRNLTECSVKDDHNLVIVCHFSNHSIALKVLKIERIIHKNWTEISAGDKQGISEEGKLSAITRFDEERVVQILDVEKMISDVFPSLKDLDDLTLRCIEAIQSQKLILIAEDSLSALKTLEKIVQTLELRYLAFPNGRELLDYLYEKEHYQQVGVVITDLEMPNVSGFEVLKTIKADHRTEHLPVIINSSMSSDSNRQLAQSLEADGFVVKSNILEIHEMLKKTLS
>NC_017063.1|WP_001256455.1|704784_706518_-|aspartate--tRNA-ligase
MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKALEVRSEFVLVAKGRVRLRGVGLENPKLKTGKIEIVLEELVIENKSATPPIEIGNKSVNEDLRLKYRYLDLRSLNAYEIFKLRSEVALITRNALAQKGFLEIETPILSKTTPEGARDYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQIDAEMSFCSENDVMGVVEDLLQEIFKAIGHTISTPFKRMPYKEAMENYGSDKPDLRFELPLIEVGDCFMDSSNAIFSNIAKDSKHKRIKALNVKGADVIFSRSVLKELEEFVRQFGAQGLAYLQIKENEVKGPLVKFLSEKGLKNILERTDAQVGDIVFFGAGDKKIVLDYMGRLRLKVAETLDLIDKDALNFLWVVNFPMFEKTENGYHAAHHPFTMPKNIECEDIEEIEAHAYDVVLNGVELGGGSIRIHKEEMQKKVFEKINIHEEEAQKKFGFLLEALKFGAPPHGGFAIGFDRLIMLMTKSNSIRDVIAFPKTQKASCLLTDAPSPINEEQLRELHIRLRK
>NC_017063.1|WP_000811286.1|704192_704768_-|adenylate-kinase
MKQLFLIIGAPGSGKTTDAELIAKNNSETIAHFSTGDLLRAESTKKTERGLLIEKFTSQGELVPLEIVVETILSAIKSSSKRIILIDGYPRSVEQMQALDKELNAQNEVILKSVIEVEVSENTAKERVLGRSRGADDNENVFHNRMRVFLDPLAEIQNFYKAKHLHKIINGERSIEEIMNEMQKYILSFAN
>NC_017063.1|WP_000580698.1|703169_704168_-|glycosyltransferase-family-25-protein
MIGVYIISLKESQRRLDTEKLILESNEKFKDRCVFQIFDAISPKHQDFEKLLQELYDAQSLLQSDWYHSYVGAGLTLPELGCYLSHYLLWKECVKLDQPVVILEDDVVLESHFMQALENCLKSPFDFVRLYGCYWYYHETKFHVLPKEFVFPPFDYPFKNNPILEKFKKFFDVSRFLNLSTHKVIHYILKKIQKSYYATHEKETFFLEHFYLTSVYVASTAGYYLTPKGAKTFIEATERFKIIEPVDMFMDNSAYHDVANLTYVPCPVSLSEHSLDSTIQKPQKKILKSYPFPPKKSTFKNLFYYSINAEKRLKAFQQYSKQYAPLKTPKEV
>NC_017063.1|WP_001046997.1|701143_701665_-|inorganic-diphosphatase
MNLDQLEVSHDADSLCVVIEISKHSNIKYELDKESGALMVDRVLYGAQNYPANYGFVPNTLGSDGDPVDALVLSDVAFQAGSVVKARLVGVLNMEDESGMDEKLIALPIDKIDPTHSYVKDIDDLSKHTLDKIKHFFETYKDLEPNKWVKVKGFENKESAIKVLEKAIKAYQG
>NC_017063.1|WP_001064007.1|698746_700990_+|endonuclease-MutS2
MNNNTLPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPTSVKESELILIKLTKLGTLHLDEIFEIVKRLRYIVVLQNAFKTFTHLKFHERLNAIILPPFFNDLIALLDDEGQIKQGANATLDALNESLNRLKKESVKIIHHYARSKELAPYLVDTQSHLKHGYECLLLKSGFSSTIKGVVLERSANGYFYLLPESVQKIAQKIAQIGNEIDCCIVEMCQTLSRSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMVLENFSHPILKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNQIVITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETALRYGVPHFLIEKAKAFYGEDKEKLNVLIENSSALERELKQKNESLENALKEQEDLKNAWLLEMEKQKEIFHHKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILNKHKTDQEIPQIITSFQINEKARYKNESVMVIQILDKGYYLVETELGMRLKAHGSWLKQIQKPPKNKFKPPKTIVPKPKEASLHLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
>NC_017063.1|WP_000724680.1|721528_722098_-|outer-membrane-beta-barrel-protein
MKKIVFILALWAGLLGAFEPKKSHIYFGAMVGLAPIKITPKPASDSSYTAFLWGAKGGYQFAFFKAIALRGEFSYLMAIKPTAFHTINTSLLSLNMDVLSDFYTYKKYSFGVYGGLGIGYFYQSNHLGMKNSSFMGYNGLINVGLGSTIDRHHRIELGAKIPFSNTRNSFKNSYFLESVFIHAAYSYAF
>NC_017063.1|WP_000278401.1|722094_725175_-|efflux-RND-transporter-permease-subunit-HefC
MYKTAINRPITTLMFALAIVFFGTMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESKVTDKIEEAVMGIDGIKKVTSTSSKNVSIVVIEFELEKPNEEALNDVVNKISSVRFDDSNIKKPSINKFDTDSQAIISLFVSSSSVPATTLNDYAKNTIKPMLQKINGVGGVQLNGFRERQIRIYADPTLMNKYNLTYADLFSTLKAENVEIDGGRIVNSQRELSILINANSYSVADVEKIQVGNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANEIEIVDRVYEALKHIQAISPSYEIRPFLDTTSYIRTSIEDVKFDLVLGAILAVLVVFAFLRNGTITLVSAISIPISIMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHKKLEMGMSKRKASYEGVREIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIALSYVVVVTIIPMVSSVVVNPRHSRFYVWSEPFFKALESRYTRLLQWVLNHKLIISIAVVLVFVGSLFVASKLGMEFMLKEDRGRFLVWLKAKPGVSIDYMTQKSKIFQKAIEKHAEVEFTTLQVGYGTTQNPFKAKIFVQLKPLKERKKEGELGQFELMSALRKELKSMPEAKGLDTINLSEVSLLGGGGDSSPFQTFVFSHSQEAVDKSVANLKKFLLESPELKGKIEGYHTSTSESQPQLQLKILRQNANKYGVSAQTIGAVVSSAFSGTSQASVFKEDGKEYDMIIRVPDSKRVSVEDIKRLQVRNKYDKLMFLDALVEITETKSPSSISRYNRQRSVTVLAQPKAGISLGEILTQVSKNTKEWLVEGANYRFTGEADNAKETNGEFLIALATAFVLIYMILAALYESILEPFIIMVTMPLSFSGAFFALGLVHQPLSMFSMIGLILLIGMVGKNATLLIDVANEERKKGLNIQEAILFAGKTRLRPILMTTIAMVCGMLPLALASGDGAAMKSPIGIAMSGGLMISMVLSLLIVPVFYRLLAPIDDKIKRFYQNQKTLE
>NC_017063.1|WP_000619654.1|725187_725892_-|efflux-RND-transporter-periplasmic-adaptor-subunit-HefB
MIRKILIGLFLSFLSMEAGEKVYAIFNVKAMQDSKLTLDSTGIVDSIKVTEGSVVKKGDVLLLLYNQDKQAQSDSTEQQLIFAKKQYQRYSKIGGAVDKNTLEGYEFTYRRLESDYAYSIAVLNKTILRAPFDGVIASKNIQVGEGVSANNTVLLRLVSHARKLVIEFDSKYINAVKVGDTYTYSIDGDSNQHEAKITKIYPTVDENTRKVSAEALLSKPMAVGLFGDGFIQTK
>NC_017063.1|WP_001092149.1|725902_727336_-|efflux-RND-transporter-outer-membrane-subunit-HefA
MNTIIRYASLWGLCVTLTLAQTPSKTPDEIKQILNNYSHKNLKLIDPPTSSLEATPSFLSSPKETATTINQEIAKYHEKSDKAALGLYELLKGATTNLSLQAQELSVKQAMKNHTIAKAMFLPTLNASYNFKNEARDTPEYKHYNTQQLQAQVTLNVFNGFSNVNNVKEKSATYRSTVANLEYSRQSVYLQVVQQYYEYFNNLARMIALQKKLEQIKTDIKRVTKLYDKGLTTIDDLQSLKAQGNLSEYDILDMQFALEQNRLTLEYLTNLSVKNLKKTTIDAPNLQLRERQDLVSLREQISALRYQNKQLNYYPKIDVFDSWLFWIQKPAYATGRFGNFYPGQQNTAGVTATLNIFDDIGLSLQKQSIMLGQLANEKNLAYKKLEQEKDEQLYRKSLDIARAKIESSKASLDAANLSFANIKRKYDANLVDFTTYLRGLTTRFDAEVAYNLALNNYEVQKANYIFNSGHKIDDYVH
>NC_017063.1|WP_000972529.1|727344_728367_-|uroporphyrinogen-decarboxylase
MMIFIDACFRKETPYTPIWMMRQAGRYLSEYQESRKKAGSFLELCKNSNLATEVTLQPVEILGVDAAILFSDILVVPLEMGLNLEFIPKKGPHFLETITDLKSVESLKVGAYKQLNYVYDTISQTRQKLSKEKALIGFCGSPWTLATYMIEGEGSKSYAKSKKMLYSEPEVLKALLEKLSLELIEYLSLQIQAGVNAVMIFDSWASTLEKEAYLKFSWDYLKKISKELKKRYAHIPVILFPKGIGAYLDSIDGEFDVFGVDWGTPLEVAKKILGGKYVLQGNLEPTRLYDKNALEEGVEKILKVMGNQGHIFNLGHGMLPDLPRENAKYLVQLVHAKTRR
>NC_017063.1|WP_080012239.1|728432_729002_-|hypothetical-protein
MAKKDGDFFKPLEPTKKYFGSFKIGYLYQHAETTKRSPIRPKNRPPILMDKTYHDASLGFQAGYILKKNALLGGYLDAGMGDSYFMSAGLVAGVRLFKGWVIPKIALGYQLQILGAKIDKYQFNIQSAVGSVGLFFNAAKNFGLSIEARGGIPFYFIQSKFSKAFGTPRLNIYSVGITFTFYDFTRFLG
>NC_017063.1|WP_000887256.1|729046_729703_-|3-methyladenine-DNA-glycosylase
MLDSFEILKALKSLDLLKNAPTWWWPNALKFEALLGAVLTQNTKFEAVLKSLENLKNAFILENDDEINLKKIAYIEFSKLAECVRPSGFYNQKAKRLIDLSKNILKDFQSFENFKQEVTREWLLDQKGIGKESADAILCYACAKEVMVVDKYSYLFLKKIGIEIEDYDELQHFFEKGVQENLNSALALYENTIPLAQLYARFHGKIVEFSKQKLELKL
>NC_017063.1|WP_000885496.1|729820_731353_-|flagellin-A
MAFQVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQASSLGQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQGLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRIATGALITASGDISLTFKQVDGVNDVTLESVKVSSSAGTGIGVLAEVINKNSNRTGVKAYASVITTSDVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGVEAYTDQKGRLNLRSIDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINVVSASDSQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSLGSGVTTLRGAMVVIDIAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRDVDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLLT
>NC_017063.1|WP_001194402.1|731516_732413_+|ABC-transporter-ATP-binding-protein
MQTPMDTIKNIPLRTFILLYKSSPKCVVLASITVLFIGIIPSINILVMIRLIDIVVDLLQNHTHFEYSLLLPTLLLWGALLFLTHVFSGISSSLQTIIAEQFSINIITQLANKLTKVKNLNFFENKDHTIKLNAIHNGLHIRPLNYVSNLFFNLQRIIGLISLFGILFSISIYLPFIMIFATMPCILISNHIAKKHSASIDKLQDQKESMQNYLCSGLDIQKNKDNLLFNFMLNFHHKFIETKELYLNNFVKVAQKNLIFIIYADVLITTLSIALFFLMVFIILSKSCGGNCWVYPSI
>NC_017063.1|WP_000467805.1|733366_734668_+|hemolysin
MFGNKQLQLQISQKDSEIAELKKEVNLYQSLLNLCLHEGFVGIKNNKVVFKSGNLASLSNLEEQSVHFKENAESVNLQGVSYSLKSQNIDGVQYFSLAKNTSCVGEYHKNDLFKTFCASLKEGLENAQESMQYFHQETGLLLNAAKNGEAHSTEGLGTVNKTGQDIESLYEKMQNATSLADSLNQRSNEITQVISLIDDIAEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQKATKEIAVVVKSMQQEANDIQTNTHDINSIVGSIKGDVEELKSTVKNNMIVAQAAKYTIYNINNRVFCGLAKLDHVVFKNNLYGMVFGLNSFDITSHKNCRLGKWYYEGAGKENFSNTSGYRALESHHASVHAEANDLVKAVQEDHITDSKYLEHKVHLMEDSAKHVKENIDKMFYEKQDELNKIIEKIQKGE

Crispr_ID: NC_017063_3

• CRISPR_ID: NC_017063_3
• CRISPR_location: 1034934-1035175
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017063_3

Consensus_repeat	Method
AAACACCCACCATCATAATTTAATTCACAAGCTTTAGAGTAGTATTGAATGGCTTT	PILER-CR

spacers of NC_017063_3

>3.1|1034990|40|NC_017063|PILER-CR
TTTTAAGTCTTCCCTATCATGATATAATCCCCCTAACACA
>3.2|1035086|51|NC_017063|PILER-CR
AAAACTTCTTGTTTGTTCGCTAGTTTTCCATCTTCTCTTGCTAAAAATATT

CRISPR arrays and Neighbor proteins around NC_017063_3

CRISPR arrays

The CRISPR arrays of NC_017063_3

>merge|NC_017063|3|1034934-1035175|PILER-CR
AAACACCCATGTTGATCATTTAATCCACAAGCTTTAGAGTAGTATTGAATGGCTTTTTTTAAGTCTTCCCTATCATGATATAATCCCCCTAACACAAAACACCCACTACCACTATTTAATTCACAAGCTTTAGAGAAAACTTCTTGTTTGTTCGCTAGTTTTCCATCTTCTCTTGCTAAAAATATTACACACCCTCCATCATAATCTAATTCACACGCTTTAGAATAGTATTGAATGGCTTT

>NC_017063|3|1|1034934-1035175|PILER-CR
AAACACCCATGTTGATCATTTAATCCACAAGCTTTAGAGTAGTATTGAATGGCTTT	TTTTAAGTCTTCCCTATCATGATATAATCCCCCTAACACA
AAACACCCACTACCACTATTTAATTCACAAGCTTTAGAGAAAACTTCTTGTTTGTT	CGCTAGTTTTCCATCTTCTCTTGCTAAAAATATTACACACCCTCCATCATA
ATCTAATTCACACGCTTTAGAATAGTATTGAATGGCTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017063.1|WP_001117174.1|1032656_1033538_+|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|223638
NC_017063.1|WP_000051414.1|1036916_1037150_-|cell-division-topological-specificity-factor-MinE	unknown	unknown	gnl|CDD|188120
NC_017063.1|WP_000201863.1|1025769_1026801_-|flagellar-motor-switch-protein-FliG	unknown	unknown	gnl|CDD|272961
NC_017063.1|WP_000829840.1|1028560_1029223_-|hypothetical-protein	unknown	unknown	gnl|CDD|239486
NC_017063.1|WP_001201378.1|1042269_1042959_-|pseudaminic-acid-cytidylyltransferase	unknown	unknown	gnl|CDD|274660
NC_017063.1|WP_000833903.1|1039996_1040935_+|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl|CDD|224577
NC_017063.1|WP_000603009.1|1023153_1025010_-|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl|CDD|129308
NC_017063.1|WP_000840105.1|1036109_1036910_-|DNA-protecting-protein-DprA	unknown	unknown	gnl|CDD|273238
NC_017063.1|WP_000810750.1|1031106_1032657_+|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl|CDD|273193
NC_017063.1|WP_000364705.1|1026813_1028517_-|flagellar-basal-body-M-ring-protein-FliF	unknown	unknown	gnl|CDD|129310
NC_017063.1|WP_000056266.1|1025006_1025783_-|flagellar-assembly-protein-FliH	unknown	unknown	gnl|CDD|235850
NC_017063.1|WP_001019035.1|1037146_1037953_-|septum-site-determining-protein-MinD	unknown	unknown	gnl|CDD|225447
NC_017063.1|WP_001207763.1|1037976_1038969_-|ketol-acid-reductoisomerase	unknown	unknown	gnl|CDD|235491
NC_017063.1|WP_000699901.1|1034219_1034558_-|hypothetical-protein	unknown	unknown	unknown
NC_017063.1|WP_000599208.1|1035708_1036113_-|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl|CDD|234639
NC_017063.1|WP_080012213.1|1041406_1042300_-|CMP-N-acetylneuraminic-acid-synthetase	unknown	unknown	gnl|CDD|226488
NC_017063.1|WP_000742656.1|1040867_1041410_-|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase	unknown	unknown	gnl|CDD|274661
NC_017063.1|WP_000038877.1|1033675_1034236_-|hypothetical-protein	unknown	unknown	unknown
NC_017063.1|WP_001168235.1|1039217_1040000_+|NAD+-synthase	unknown	unknown	gnl|CDD|184435
NC_017063.1|WP_000373252.1|1029481_1031098_+|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl|CDD|235437

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017063.1|WP_001117174.1|1032656_1033538_+|RluA-family-pseudouridine-synthase	gnl|CDD|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	5.61565e-68
NC_017063.1|WP_000051414.1|1036916_1037150_-|cell-division-topological-specificity-factor-MinE	gnl|CDD|188120	TIGR01215, Cell_division_topological_specificity_factor, cell division topological specificity factor MinE. This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division].	1.07135e-25
NC_017063.1|WP_000201863.1|1025769_1026801_-|flagellar-motor-switch-protein-FliG	gnl|CDD|272961	TIGR00207, Flagellar_motor_switch_protein_FliG, flagellar motor switch protein FliG. The fliG protein along with fliM and fliN interact to form the switch complex of the bacterial flagellar motor located at the base of the basal body. This complex interacts with chemotaxis proteins (eg CHEY). In addition the complex interacts with other components of the motor that determine the direction of flagellar rotation. The model contains putative members of the fliG family at scores of less than 100 from Agrobacterium radiobacter and Sinorhizobium meliloti as well as fliG-like genes from treponema pallidum and Borrelia burgdorferi. That is why the suggested cutoff is set at 20 but was set at 100 to construct the family. [Cellular processes, Chemotaxis and motility].	1.39884e-165
NC_017063.1|WP_000829840.1|1028560_1029223_-|hypothetical-protein	gnl|CDD|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	5.33165e-15
NC_017063.1|WP_001201378.1|1042269_1042959_-|pseudaminic-acid-cytidylyltransferase	gnl|CDD|274660	TIGR03584, PseF, pseudaminic acid cytidylyltransferase. The sequences in this family include the pfam02348 (cytidyltransferase) domain and are homologous to the NeuA protein responsible for the transfer of CMP to neuraminic acid. According to, this gene is responsible for the transfer of CMP to the structurally related sugar, pseudaminic acid which is observed as a component of sugar modifications of flagellin in Campylobacter species. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci.	4.50117e-119
NC_017063.1|WP_000833903.1|1039996_1040935_+|tetraacyldisaccharide-4'-kinase	gnl|CDD|224577	COG1663, LpxK, Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane].	1.38051e-90
NC_017063.1|WP_000603009.1|1023153_1025010_-|1-deoxy-D-xylulose-5-phosphate-synthase	gnl|CDD|129308	TIGR00204, 1-deoxy-D-xylulose-5-phosphate_synthase, 1-deoxy-D-xylulose-5-phosphate synthase. DXP synthase is a thiamine diphosphate-dependent enzyme related to transketolase and the pyruvate dehydrogenase E1-beta subunit. By an acyloin condensation of pyruvate with glyceraldehyde 3-phosphate, it produces 1-deoxy-D-xylulose 5-phosphate, a precursor of thiamine diphosphate (TPP), pyridoxal phosphate, and the isoprenoid building block isopentenyl diphosphate (IPP). [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine, Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	0
NC_017063.1|WP_001207763.1|1037976_1038969_-|ketol-acid-reductoisomerase	gnl|CDD|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	3.92661e-179
NC_017063.1|WP_000810750.1|1031106_1032657_+|single-stranded-DNA-specific-exonuclease-RecJ	gnl|CDD|273193	TIGR00644, recJ, single-stranded-DNA-specific exonuclease RecJ. All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_017063.1|WP_000364705.1|1026813_1028517_-|flagellar-basal-body-M-ring-protein-FliF	gnl|CDD|129310	TIGR00206, Flagellar_M-ring_protein, flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF). Component of the M (cytoplasmic associated) ring, one of four rings (L,P,S,M) which make up the flagellar hook-basal body which is a major portion of the flagellar organelle. Although the basic structure of the flagella appears to be similar for all bacteria, additional rings and structures surrounding the basal body have been observed for some bacteria (eg Vibrio cholerae and Treponema pallidum). [Cellular processes, Chemotaxis and motility].	0
NC_017063.1|WP_000056266.1|1025006_1025783_-|flagellar-assembly-protein-FliH	gnl|CDD|235850	PRK06669, fliH, flagellar assembly protein H; Validated.	2.91415e-66
NC_017063.1|WP_001019035.1|1037146_1037953_-|septum-site-determining-protein-MinD	gnl|CDD|225447	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning].	2.4675e-150
NC_017063.1|WP_080012213.1|1041406_1042300_-|CMP-N-acetylneuraminic-acid-synthetase	gnl|CDD|226488	COG3980, spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase [Cell envelope biogenesis, outer membrane].	5.74844e-108
NC_017063.1|WP_000599208.1|1035708_1036113_-|Holliday-junction-resolvase-RuvX	gnl|CDD|234639	PRK00109, PRK00109, Holliday junction resolvase RuvX.	1.03025e-37
NC_017063.1|WP_000742656.1|1040867_1041410_-|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase	gnl|CDD|274661	TIGR03585, PseH, UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase. Sequences in this family are members of the pfam00583 (GNAT) superfamily of acetyltransferases and are proposed to perform a N-acetylation step in the process of pseudaminic acid biosynthesis in Campylobacter species. This gene is commonly observed in apparent operons with other genes responsible for the biosynthesis of pseudaminic acid and as a component of flagellar and exopolysaccharide biosynthesis loci. Significantly, many genomes containing other components of this pathway lack this gene, indicating that some other N-acetyl transferases may be incolved and/or the step is optional, resulting in a non-acetylated pseudaminic acid variant sugar.	1.40689e-59
NC_017063.1|WP_000840105.1|1036109_1036910_-|DNA-protecting-protein-DprA	gnl|CDD|273238	TIGR00732, Protein_smf, DNA protecting protein DprA. Disruption of this gene in both Haemophilus influenzae and Helicobacter pylori drastically reduces the efficiency of transformation with exogenous DNA, but with different levels of effect on chromosomal (linear) and plasmid (circular) DNA. This difference suggests the DprA is not active in recombination, and it has been shown not to affect DNA binding, leaving the intermediate step in natural transformation, DNA processing. In Strep. pneumoniae, inactivation of dprA had no effect on the uptake of DNA. All of these data indicated that DprA is required at a later stage in transformation. Subsequently DprA and RecA were both shown in S. pneumoniae to be required to protect incoming ssDNA from immediate degradation. Role of DprA in non-transformable species is not known. The gene symbol smf was assigned in E. coli, but without assignment of function. [Cellular processes, DNA transformation].	2.68026e-95
NC_017063.1|WP_001168235.1|1039217_1040000_+|NAD+-synthase	gnl|CDD|184435	PRK13980, PRK13980, NAD synthetase; Provisional.	3.40687e-124
NC_017063.1|WP_000373252.1|1029481_1031098_+|CTP-synthase-(glutamine-hydrolyzing)	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0

Protein sequences

>NC_017063.1|WP_000699901.1|1034219_1034558_-|hypothetical-protein
MKIMHQVKDFLDFCKQTIHKNSNEAFQKTKRVLFKEKSQKIREQAVKIVEKRLKKEGMQLSDFNEEELKIMFEAEEKRLLEQIHAKELKEKQEKTTKHFKEIWEKGDNEQEK
>NC_017063.1|WP_000038877.1|1033675_1034236_-|hypothetical-protein
MSKKNSVISGLMNFFSEKNERWLLAHRHTRGFVIVAWLFRFKSIAFSIFITLLVILVDIWVYSDVRQFLLDTSSSFIWLLIALLIKWGVIIISARKCYQFSQKMFALIQRKRQIRENLKNRSNRKDTKNFEKLSSIAEEIISKKQEESHHKEDSNNENHKDKLSSITEEMILKKQEELKARKDKGD
>NC_017063.1|WP_001117174.1|1032656_1033538_+|RluA-family-pseudouridine-synthase
MPFVEEEFEILKPTKALFLVRDVLKCSLKEAQRHLDKQRLKQNQQAVRKSQIIQGVVRLIYFKPNEKQEKLVFETKDFGVFDKPAQVYTHPKGYFYHESLLDCIQSHLGKNAHPAHRLDYETSGLVLAGKTLQSVKDLKALFMQKKVKKTYLALAHGLVDKSIIINKPILTPQNIQKDLRIRSQISPLGKPSITLVEPLSYNPFLDISLLKITPLTGRTHQIRLHLSSVDHRIVGEGLYGVADENAREYLQLKRENNAPTLMLHAASLEFEFKGAIYQIASPMPERFMPFLKD
>NC_017063.1|WP_000810750.1|1031106_1032657_+|single-stranded-DNA-specific-exonuclease-RecJ
MKQKLKAQIKERVASIAYNEKGFPSPFLFKDLKKAALKIIEAMRANTEILVVGDYDADGVISSAIMAKFFESLNYKHVRIAIPNRFMDGYGISKKFLEKHHAPLIITVDNGINAFEAARFCKEKNYTLIITDHHCLNNDEVPDAYAVINPKQPDCDFIQKEVCGALVAFYLCYGIHQLLGKEKSHSSELLCLAGVATIADMMPLTFFNRFLVSKALYFLQKESLGAMGFLRQREVFRKRSLKASDISFNIAPLINSAGRMQDAKMALDFLSANNFQDGYSLYERLKACNLKRKMIQQQVFEEAFKHAMVGEKIIIAFKDNWHEGVLGIVASKLVEATQKPSLVFTFKEGVYKGSGRSSPNIDLIDALNGVSSLLLGYGGHRQACGLSVGKNNIVSLFETLENFDFKVLPFCEKEPPLTLKLKDIDRELLEIIEAGEPYGQENPEPLFQARNLEVIEEKIIKESHQILRFKDKECVKEAIYFNAERFLKAGEKVSVLFSVELDECSNEPKMFVKSLL
>NC_017063.1|WP_000373252.1|1029481_1031098_+|CTP-synthase-(glutamine-hydrolyzing)
MDRAKFIFVTGGVLSSLGKGISSSSIATLLQHCNYQVSILKIDPYINIDPGTMSPLEHGEVFVTSDGAETDLDIGHYERFLNRNLTRLNNFTTGQIFSSVIENERKGEYLGKTIQIVPHVTDEIKRRIRSAAKGLDFLIVEVGGTVGDMEGMFYLEAIRQLKLELGNEKVINVHVTLIPYIQTTNELKTKPTQHSVQELRRLGVTPQIILARSPKPLDKELKNKIALSCDVEQDSVIVATDTKSIYACPILFLQEGILTPIARRFNLNKLHPKMAAWNTLVEKIIAPKHKVKIGFVGKYLSLKESYKSLIEALIHAGAHLDTQVNIEWLDSENFNEKTDLESVDAILVPGGFGERGIEGKICAIQRARVEKLPFLGICLGMQLAIVEFCRNVLGLKGANSTEFNQRCEYPVVYLIGDFMDQNHQKQVRTYNSPLGGTMRLGEYECEIMPNSLLEKAYKKPNIKERHRHRYEINPKYRQEWEDKGLKVVGFGANHLIEAIELEDHPFFVGVQFHPEFTSRLQSPNPIILDFIKSALSKS
>NC_017063.1|WP_000829840.1|1028560_1029223_-|hypothetical-protein
MAENSFKNVSAQSKVFFLLPVKTLFLLGGVFSAFFILIAGLVFFDYANSMDHAIFNLMRSNSSNPILDQTLQRIVFLGSSQFVLPLSLLVGVFLSLYRKNLALGVWFVLSVVIFEALLESLKHLLAHSIQWLSHSANFPSAIALSLTLFYGLLVLLIPHLITHQIFQNILSCSLLGLILLIGLALIVLGVSFSSVLGGVCLGALGACFSIGIYLSVFQKI
>NC_017063.1|WP_000364705.1|1026813_1028517_-|flagellar-basal-body-M-ring-protein-FliF
MDLKVLLQRIVDFFIKLNKKQKIALIAAGVLITALLVFLLLYPFKEKDYAQGGYGVLFERLDSSDNALILQHLQQNQIPYKILKDDTILIPKDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFDQNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKLKPDMKLSPTQILGIKNLIAAAVPKLTIENVKIVNENGESIGEGDILENSKELALEQLHYKQNFENILENKIVNILAPIVGGKNKVVARVNAEFDFSQKKSTKETFDPNNVVRSEQNLEEKKEGASKKQVGGVPGVVSNIGPVQGLKDNKEPEKYEKSQNTTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIALKDGANVLEYEPLSDESLKKINALVKQAIGYNQNRGDDVAVSNFEFNPIAPMLDNATLSEKIMHKTQKILGSFTPLIKYILVFIVLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNATFSEEEVRYEIILEKIRGTLKERPDEIAMLFKLLIKDEISSDSAKG
>NC_017063.1|WP_000201863.1|1025769_1026801_-|flagellar-motor-switch-protein-FliG
MATKLTPKQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQIGAAVLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEARKVMDKLTKSLQTQKNFAYLGKIKPQQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRVSTVLENKLESLTSYKIEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMFTFEDIVKLDNFAIREILKVADKKDLSLALKTSTKDLTDKFLNNMSSRAAEQFVEEMQYLGAVKIKDVDVAQRKIIEIVQSLQEKGVIQTGEEEDVIE
>NC_017063.1|WP_000056266.1|1025006_1025783_-|flagellar-assembly-protein-FliH
MSLNSRKNLIQKDHLNKHDIQKYEFKSMANLPPKTNPNGASLETPNPQEPLEKKAIENDLIDCLLKKTDELSSHLVKLQMQFEKAQEESKVLIENAKNDGYKIGFKEGEEKMRNELTHSVNEEKNQLLHAITALDEKMKSSENHLMALEKELSAIAIDIAKEVILKEVEDNSQKVALALAEELLKNVLDATDIHLKVNPLDYPYLNEHLQNASKIKLESNEAISKGGVMITSSNGSLDGNLMERFKTLKESVLENFKV
>NC_017063.1|WP_000603009.1|1023153_1025010_-|1-deoxy-D-xylulose-5-phosphate-synthase
MILQNKTFDLNPNDIAGLELVCQTLRNRILEVVSANGGHLSSSLGAVELIVGMHALFDCQKNPFIFDTSHQAYAHKLLTGRFESFSTLRQFQGLSGFTKPSESAYDYFIAGHSSTSVSIGVGVAKAFCLKQVLGMPIALLGDGSISAGIFYEALNELGDRKYPMIMILNDNEMSISTPIGALSKALSQLMKGPFYQSFRSKVKKILSTLPESVNYLASRFEESFKLITPGVFFEELGINYIGPINGHDLSAIIETLKLAKELKEPVLIHAQTLKGKGYKIAEGRYEKWHGVGPFDLDTGLSKKSKSTILSPTEAYSNTLLELAKKDEKIVGVTAAMPSGTGLDKLIDAYPLRFFDVAIAEQHALTSSSAMAKEGFKPFVSIYSTFLQRAYDSIVHDACISSLPIKLAIDRAGIVGEDGETHQGLLDVSYLRSIPNMVIFAPRDNETLKNAVRFANEHDSSPCAFRYPRGSFALKEGVFEPSGFVLGQSELLKKEGEILLIGYGNGVGRAHLVQLALKEKNIECALLDLRFLKPLDQNLSAIIAPYQKLYVFSDNYKLGGVASAILEFLSEQNILKPVKSFEIIDEFIMHGNTALVEKSLGLDTESLTDAILKDLGQER
>NC_017063.1|WP_000599208.1|1035708_1036113_-|Holliday-junction-resolvase-RuvX
MILACDVGLKRIGIAMLLNGVILPLEAILRHNRNQASRDLSDLLREKNIQVLVVGKPNESYADTNARIEHFIKLVDFKGEIVFINEDNSSIEAYENLEHLGKKNKRLATKDGRLDSLSACRILERYCQQVLKNH
>NC_017063.1|WP_000840105.1|1036109_1036910_-|DNA-protecting-protein-DprA
MKSNFQYSALENIPKAFDILKDPPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGVDIIAQENALPTTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLKSGSMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMKDEFLEYCTKNPSYEEAYLKFGDKLLEYELLGKIKRINHLVVLA
>NC_017063.1|WP_000051414.1|1036916_1037150_-|cell-division-topological-specificity-factor-MinE
MSLFDFFKNKGSAATATDRLKLILAKERTLNLPYMEEMRKEIIAVIQKYTKSSDIHFKTLDSNQSVETIEVEIILPK
>NC_017063.1|WP_001019035.1|1037146_1037953_-|septum-site-determining-protein-MinD
MAIVVTITSGKGGVGKSTTTANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKTKNLSFLAASQSKDKNILDKEKVAILINALKADFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVIGIIDAKSNRAKRGEEVHKHLIINRLKPELVANGEMIPIEEVLKILCLPLIGIIPEDHHIISATNKGEPVIRTDCESAKAYQRITRRILGEEVEYVEFKAKRGFFSALKGIFS
>NC_017063.1|WP_001207763.1|1037976_1038969_-|ketol-acid-reductoisomerase
MALPVYYDKDIDLGVIQSLQVGIIGYGAQGEAQALNLRDSKVKVRIGLYQGSLSVSKAKKEGFEVLGVKELVQQSDVIMALLPDELHKEVLEKEVIPFLKEGQIVGFAHGFSVHFNQVVIPKGVGAILVAPKGPGSALREEYLKNKGLYHLIAIEQESSKNNAKAVALSYAKAMGGGRMGVLETSFKEECESDLFGEQAVLCGGLEAIVRMGFETLIKAGYPEELAYFECVHEVKLVADLLHYKGVEGLRKHISNTAEFGAIKNREPMANLLEKRMQKILKKIQNGAFAKDFLLEKSLNYPRLNTERKALKETKIEQIGEILRAPFNHKK
>NC_017063.1|WP_001168235.1|1039217_1040000_+|NAD+-synthase
MQKDYQKLIAYLCDFLEKEVQKKGFKKVVYGLSGGLDSAVVGVLCQKVFKENAHALLMPSSVSMPESKADALNLCEMFSIPYTEYSIAPYDKIFGSHFKDASLTRKGNFCARLRMAFLYDYSLKSDSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELAYYLNIPKKILNKPPSADLFVGQSDEKDLGYPYSVIDPLLKDIEALFQTKPIHLETLTQLGYDEILVKNIISRIQKNAFKLELPTIAKRFNPE
>NC_017063.1|WP_000833903.1|1039996_1040935_+|tetraacyldisaccharide-4'-kinase
MKSDKPFLERYFYDPTLLQKGLIFALYPFSLIYQFIATIKRKTAKKHDFKIPIISIGNLIAGGSGKTPFILEIAPRYQEVAVVSRGYQRDSKGLVVVSVKGNILVPQKTAGDEAYLLALNLKQASVIVSEKRELGVLKALELGAKIVFLDDGFRFNFNQFNLLLKPKVPPYYPFCLPSGLYRESIKSYKEAHLIITEDKDYKRITSISHPTKRMLLVTAIANPSRLDAFLPKEVVKKLYFIDHAPFDLEFLEKEFYQNNATSLLVTSKDLVKLQDCKLPLSVLDLKLEICPKVLEEIDRYILSYPCNTKECL
>NC_017063.1|WP_000742656.1|1040867_1041410_-|UDP-4-amino-4,-6-dideoxy-N-acetyl-beta-L-altrosamine-N-acetyltransferase
MKKNYSYGNIQAIDFTNLNDGEKLLVLEFRNHPNTALWMYSAFISLKTHLQFIEDLKNSPNHRYFLFKEKGVYLGVGSITKINFFHKHGYLGIYKNPFLKNKGETILKALECIAFEEFQLHSLHLEVMETNYKAIAFYEKNHYELEGRLKGFISKDKEFIDILLYYKDKKGYNDQSLLKL
>NC_017063.1|WP_080012213.1|1041406_1042300_-|CMP-N-acetylneuraminic-acid-synthetase
MQPFEKRMPVKILCDCFLTSGLGHVRRCEKILSFIEKLGIKADLYLHKQNNISAFLEGVGNNDFLIADSYRLNSKDFYLLKEKAKSLMVIEDEEHAKGFYPKNTKIMNFTLNALKHYHHLSKDYQYYLGVGFYPVDARFVYERPINTENKEVLITLGGSEQKTLKEIVKILENKNVNLHIISPYIPKNPPKNTRYYSPLNPLEFSSLMKSCACAISASGQTLYELALSQTPSLILPIASNQIIQSQEFESLGIFKQTSLKTLAKDFENLQIQKNQAWAKTLAFGSELEGALREFLEI
>NC_017063.1|WP_001201378.1|1042269_1042959_-|pseudaminic-acid-cytidylyltransferase
MRAIAIVLARSSSKRIKNKNIIDFFNKPMLAYPIETALNSKLFEKVFISSDSMEYVNLAKNYGASFLNLRPKILADDRATTLEVMAYHMKELELKDEDIACCLYGASVFLQEKHLKNAFETLKQNQNTDYVFTCSPFSVSPYRSFSLENGVQMAFKEHLNTRTQDLKTLYHDAGLLYMGKAQAFKEMRPIFSPNSIALELLPLEVQDIDTLEDLELAKLKYSRLKNACQ

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017063_1	1.1|381642|26|NC_017063|CRT	381642-381667	26	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	1090169-1090194	4	0.846
NC_017063_1	1.1|381642|26|NC_017063|CRT	381642-381667	26	AP014693	Ralstonia phage RSL2 DNA, complete sequence	170281-170306	5	0.808
NC_017063_1	1.2|381696|29|NC_017063|CRT	381696-381724	29	NC_048674	Aeromonas phage AS-sw, partial genome	156293-156321	7	0.759
NC_017063_1	1.2|381696|29|NC_017063|CRT	381696-381724	29	KT962247	Cellulophaga phage phi17:2_18, complete genome	34850-34878	8	0.724
NC_017063_1	1.2|381696|29|NC_017063|CRT	381696-381724	29	KT962246	Cellulophaga phage phi4:1_18, complete genome	34451-34479	8	0.724
NC_017063_1	1.2|381696|29|NC_017063|CRT	381696-381724	29	KT962245	Cellulophaga phage phi4:1_13, complete genome	34451-34479	8	0.724
NC_017063_1	1.2|381696|29|NC_017063|CRT	381696-381724	29	KC821632	Cellulophaga phage phi4:1, complete genome	34451-34479	8	0.724
NC_017063_1	1.2|381696|29|NC_017063|CRT	381696-381724	29	NC_021798	Cellulophaga phage phi17:2, complete genome	34850-34878	8	0.724
NC_017063_2	2.1|719119|30|NC_017063|CRISPRCasFinder	719119-719148	30	NZ_LT960613	Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence	40156-40185	8	0.733
NC_017063_2	2.1|719119|30|NC_017063|CRISPRCasFinder	719119-719148	30	MN693417	Marine virus AFVG_25M193, complete genome	5683-5712	8	0.733

1. spacer 1.1|381642|26|NC_017063|CRT matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 4, identity: 0.846

ggtgtcgttattaaagctaacattgt	CRISPR spacer
cgtgtcgttactaaagctaatattct	Protospacer
 *********.*********.*** *

2. spacer 1.1|381642|26|NC_017063|CRT matches to AP014693 (Ralstonia phage RSL2 DNA, complete sequence) position: , mismatch: 5, identity: 0.808

ggtgtcgttattaaagctaacattgt	CRISPR spacer
ggtggcgttattaaagctaacgtcaa	Protospacer
**** ****************.*.. 

3. spacer 1.2|381696|29|NC_017063|CRT matches to NC_048674 (Aeromonas phage AS-sw, partial genome) position: , mismatch: 7, identity: 0.759

agcactgttattaaaagcagattggacgc	CRISPR spacer
tgtcatattatcaaaagcagattggacgt	Protospacer
 *.  *.****.****************.

4. spacer 1.2|381696|29|NC_017063|CRT matches to KT962247 (Cellulophaga phage phi17:2_18, complete genome) position: , mismatch: 8, identity: 0.724

agcactgttattaaaagcagattggacgc	CRISPR spacer
agcactgttattaaaaccatatttttttt	Protospacer
**************** ** ***   . .

5. spacer 1.2|381696|29|NC_017063|CRT matches to KT962246 (Cellulophaga phage phi4:1_18, complete genome) position: , mismatch: 8, identity: 0.724

agcactgttattaaaagcagattggacgc	CRISPR spacer
agcactgttattaaaaccatatttttttt	Protospacer
**************** ** ***   . .

6. spacer 1.2|381696|29|NC_017063|CRT matches to KT962245 (Cellulophaga phage phi4:1_13, complete genome) position: , mismatch: 8, identity: 0.724

agcactgttattaaaagcagattggacgc	CRISPR spacer
agcactgttattaaaaccatatttttttt	Protospacer
**************** ** ***   . .

7. spacer 1.2|381696|29|NC_017063|CRT matches to KC821632 (Cellulophaga phage phi4:1, complete genome) position: , mismatch: 8, identity: 0.724

agcactgttattaaaagcagattggacgc	CRISPR spacer
agcactgttattaaaaccatatttttttt	Protospacer
**************** ** ***   . .

8. spacer 1.2|381696|29|NC_017063|CRT matches to NC_021798 (Cellulophaga phage phi17:2, complete genome) position: , mismatch: 8, identity: 0.724

agcactgttattaaaagcagattggacgc	CRISPR spacer
agcactgttattaaaaccatatttttttt	Protospacer
**************** ** ***   . .

9. spacer 2.1|719119|30|NC_017063|CRISPRCasFinder matches to NZ_LT960613 (Vibrio tapetis subsp. tapetis isolate Vibrio tapetis CECT4600 plasmid P, complete sequence) position: , mismatch: 8, identity: 0.733

aacattcccattaaaatccacttgcttggc	CRISPR spacer
tttgttctcattaaaatccccttgctttgg	Protospacer
  ..***.*********** ******* * 

10. spacer 2.1|719119|30|NC_017063|CRISPRCasFinder matches to MN693417 (Marine virus AFVG_25M193, complete genome) position: , mismatch: 8, identity: 0.733

aacattcccattaaaatccacttgcttggc	CRISPR spacer
ataattcctattaaaatccacttgtggtgt	Protospacer
*  *****.***************.   *.

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	180659 : 185646	6	Helicobacter_phage(50.0%)	transposase	NA
DBSCAN-SWA_2	1514966 : 1525917	9	uncultured_Caudovirales_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_017063|180659:185646|DBSCAN-SWA
AATGAGCAAATATAATTGCATAGATTTATTTAGTGGGGCTGGCGGTTTATCATTGGGCTTTGCGAATACAAATAGATTCAATATTTTAGCCCACATTGAGTGGGAAAAACCTATGGTTGCTACACTGAGAAACGCTTTAAACAAACGCTTCAAGATTAGTGAAAAAGAAACAAAAAAAAGAGTTATTAAATTTGATATTCAAAAAACTGATGAATTGATAAATGGCTCTTGGAGTGATGAAACTCTTAAAATTTATGGATCTGATAATGATGAAAGCGTTAGCCAATTTGGGTTAAATGGCGTAATTAGTGGTAAAAAAATAGATGTTATCTTTGGCGGTCCTCCTTGTCAAGCTTATTCTCTTGTGGGTAGAGTGCAAGATAAACACTCTATGAAATATGATTATAGGAATTATCTTTTTGAAAGTTTTGTTAAAATAGTTGATTATTACCAACCACAATGCTTTGTGTTTGAAAATGTTCCTGGCATGCTTAGCGCAAAACCGGGTAATCAATTTGTAAAAGATAGGATTTATGAATCTTTTTCAAAAATAGGGTATGAAATTAAAAAACCAAATGAAATGAAAGAGATAATCTATTCTAGCGATGATCATGAAGTCCCACAAACCAGAAAACGAGTGGTTGTATTTGGCGTTCGTAAAGATAATAAAGAATGGTTATTCAAATTTTATCAAAATCTAGACAATCTCAAATCAAAAAACCCACCGCTTAGCGTTAAAGACGCTATTGGCCATTTACCCAAGTTTAGACCACTCAAAACGCCCTTAAAAATCAATAATAAAAACATTTCTCACGAACTTATTGGCACAAATAATTTGACACAAAATTTTCCACGATATAATAATTTACGAGATTTAAAAGCGATGAAATTTTGGATTGAAAACAACATGAATAACGCTTCTGCAAAAGAAAAGCTTGACTTTTACACTAAGATTACGGGAAAAGTCTCAAACCATAACAAATACAGGAATTTAGAATGGGATAAACCATCGCCAACCTTAGTGGTGCATTTGCAAAAAGATGGTTTTATGTTTATACACCCAGAAGCCAATCAAAGCCGCTCAATCACCATAAGAGAAGCAGCGATTTTGCAGACTTTCCCTAATGATTTTGAATTTATCGGATCGCAAGCGGCTTGTTTTAAAATGATAGGCAATGCAGTGCCAGTTAATTTTGCCAAAAATATAGCCCTAGCAGTGGCAAAGGTCTTAGATGAAAAAAACTAATATAAATATTTTAGTAGCTTGTGAAGAAAGCCAAAGGGTGTGCAATGAATTTAGAAAGCTTGGTTTCAACGCTTATAGTTGTGATTTATTAGAATGTAGTGGCGGGCATCCTGAGTGGCATTTTAATTGCGATGTTTTTGAAGTGATTGGAAATAAAGGCGGTGTTTTGCAAAATGGCAAACATGCAAAAGTTTCGCAATGGGATATGATGATAGCGCACCCGCCTTGCACCTTTTTAGCTGTTAGTGGAGCGAAGTGGTATTAACACCCTAAAGATAAAGATTTGCCCATAGAACAAAAAAGACCCCACCCCAAATTCCCCAACCGTGCAAAAGACAGAGAAGAAGCTTCAAAATTCTTTATGGATTTAGTGGAAGCAAAAATCCCTTATATTGCAATAGAAAACCCCATTGGCATAATGAATACAAGATACAAAAAGCCCAATCAAATAGTCCAACCTTACCACTTTGGCGATAGCGCATCAAAAAAGACTTGTTTGTGGCTTAAAAACTTACCACCCTTAAAATATACAAATATCGTTGATCCTGGCGAGTTTATAGAATTTAAAAGCGGTAAAAAAATAGTAAAATGGTATAGCGATGGACTGACTAAAACAAAATCAGCCAAAGAGCGTCAAATTTGGAGGAGTAAAACATTTCCAGGATTTGCAAAGGCGATGGCAGAGCAGTGGGGGGAGTTTGTAAAAAATGAGATGTTTAAAAAGGTGAAAAATGAAAGTTTATCCCACTAGCGCGAAAAACTCCGTCCTTTAGGGCGGAGATGTAAGTGCTTAGACATCAGGCTATTTGAATATCGTTTCACCTAGATCCATTCGCTTTTTAGCGCATTCTATTAAAAATCAAAGTTAGCTAGTTAATGCGGTGTTTCTTGTTCTTGTATGTATTGCTTAATCATCTCTAAAGGTGCACCCCCACAACTCCCAGCGAAATAACTAGGCGACCATAAATGCTTCCCCCACAAACTAGCTTCAACGCTTTTGAAATGGTGTTGTCTAGTCAAACGACTGCTAACGCCTTTTAAAGAATTAACTAACTTACTCACGCTCACTTTTGGAGGGTAGTTGATAAGCAAATACACATGATCGCTCTCCCCATCAAATTCTACCAATTCGCTCTCAAAGTCCTTACACACTTTGGCAAACACCGATCCTAAAAAATCTATCACTTCCTTGTTGAACGCTGAACGCCTGTATTTAGTAACAAATACCAAATGCACATGCATTAAAAAAACACAATGTCTTCCGTGTCTCATATCATCAATTTTTTTCATAGACCTATTTTAACAAAAAGAGGTTAAAATACTTCTATGAAAGTCAATAAGGGTTTTAAATTCCGCTTGTATCCCACTAAAGAACAACAAGATAAATTGCAACACTGCTTTTTTGTCTATAACCAAGCTTATAATATTGGCTTGAATTTACTGCAAGAGCAATATGAAACCAACAAAGATTTACCTCCCAAAGAAAGAAAGTGGAAAAGATCAAGCGAGTTAGATAAAGCGATTAAACACCACTTGAACGCTAGGGGGTTAAGCTTTAGTAGTGTGATAGCCCAACAATCACGCATGAACGTTGAAAGGGCTTTAAAAGATGCTTTTAAAGTTAAAAACAGGGGCTTTCCTAAATTCAAAAACTCTAAATCCGCCAAACAATCTTTTTTGTGGAACAATCAAGGCTTCTCTATCAAAGAGAGCGATGAGGAACGCTTCAAGACATTCACTCTGATGAAAATGCCTTTACTCATGCGCATGCATAGAGACTTCCCCCCTAATTTTAAAGTGAAACAAATTAGTATCTCTTGCAGCCATAGAAAATATTTTGTTAGCTTTAGCGTGGAATACGAACAAGACATTACTCCCATCAAAAACCCTAAAGATTGTGTGGGGCTAGATTTGAATATCCTTGATATAGCTTGTTCTTGTGGCATAAACAACCATGAAAAACTAACGGATTTTAAGCAATACCAAACAGACATGAAAGAATTACTAGGGATAGAAATAGACAAAGAGTTGGATACTAAACGACTCATCCCTACTTATTCCAAATTGTATTCTTTAAAAAAATACTCTAAAAAATTTAAAAGATTACAAAGAAAACAAAGCCGTAGGGTGTTAAAGTCTAAACAAAACAAAACCAAATTAGGAGGTAATTTTTACAAAACCCAAAAGAAATTAAACCAAGCCTTTGACAAGTCTAGTCATCAAAAAACAGACAGATACCATAAAATCACAAGCGAACTTTCAAAGCAATTTGAATTGATAGTAGTTGAAGATTTGCAAGTAAAAAACATGACTAAAAGAGCTAAACTCAAAAATGTTAAACAAAAGAGTGGGCTTAATCAATCTATCAACAATACTTCATTCTATCAAATCATTTCTTTTTTAGATTACAAACAACAGCATAATGGCAAATTGTTAGTGAAAGTTCCCCCACAATATACGAGTAAAACTTGCCATTGTTGTGGGAATATCAACCACAAGCTTAAATTAAATCATAGGCAATATTGGTGTTTAGAATGCGGGTATAGAGAACACAGAGACATCAACGCTGCGAACAATATTTTAAGCAAAGGGTTAAGTCTTTTTGGGGTAGGAAATATCCATGCAGACTTTAAAGAACAAAGCCTTTCGTGTTAGCGTTCAATAGAATGCTTTAGTTAGGAAGCTCCTTGCTTTAGCAAGGGGTGGTTTCACTTACTTGAATCTAGCCTTTAATAAGTTTTTTAGGGATTTAAAAAAAGGTTTAGTGAGTTACCCTAAATTTAAAAAGAAAAGAGAGTTTCAAGGTTCTTTTTATATAGGGGGCGACCAAATTAAAATCATTCAAACAGCTAATACTGATTATTTAAAAATACCTAACTTACCTCCAATCAAACTCACTGAAAAACTAAGATTTCAAGGCAAAATCCATAACGCTACCATCACTCAAAAGGGCGATCATTTCTATGCTTCAATCTCTTGTGGTATTGATGAGAGTGAATACAAGCGAACCCATAAACTCCAAGAGAGTCATAATAAACTAGGGATTGATATAGGGATTAAATCCTTTGTGAGTTTGTCTAATGGCTTAAATATCTATGCCCCTAAGCCCTTAGATAAGCTTACTAGAAGGCTTGTAAGAATTAGCAGACAACTGAGTAAAAAAATCCACCCAAAAACCAAAGGGGATAAAACCAAGAAATCTAATAATTACTTAAAGCATTCTAAAAAGCTTACCCACTTGCATGAAAAAATCGCTAACATCAGACTTGATTTTTTACACAAGCTCACAAGCTCTCTTATAAGACACTCCAACTCGTTTTGTTTGGAGAGTTTGAAAGTCAAAAACATGTTTAAAAATCACAGGTTAGCTAAATCTTTAAGCGATGTTTCTATGTCTGTGTTTAACACGCTGTTAGAATATAAAGCCAGATACTCTAATAAAGAAATTCTAAGAGCTGATACTTACTATCCAAGCTCTAAGACTTGCTCTAATTGTCAAAAGGTTAAACAAGATTTAAAACTTAAAGATAGGATTTATCAATGCCTAGAGTGTGGCTTTGAATTAGATAGAGATATAAACGCTGCTATCAATCTTTTAAAGCATTTAGTAGGTAGAGTTACTGCCGAATTTACGCCTATGGACTTGACGGCTCTGTTGAATGATTTATCCAATAATCGTTTAGCAACTAGCAAGGTTGAACTAGGAATACAACAAAAATCCCAAATTGAGAGAATTTTATAG

Protein sequences of DBSCAN-SWA_1

>NC_017063|180659:185646|181890_182169_+|WP_000753490.1|DBSCAN-SWA
MKKTNINILVACEESQRVCNEFRKLGFNAYSCDLLECSGGHPEWHFNCDVFEVIGNKGGVLQNGKHAKVSQWDMMIAHPPCTFLAVSGAKWY
>NC_017063|180659:185646|182187_182655_+|WP_001121191.1|DBSCAN-SWA
MPIEQKRPHPKFPNRAKDREEASKFFMDLVEAKIPYIAIENPIGIMNTRYKKPNQIVQPYHFGDSASKKTCLWLKNLPPLKYTNIVDPGEFIEFKSGKKIVKWYSDGLTKTKSAKERQIWRSKTFPGFAKAMAEQWGEFVKNEMFKKVKNESLSH
>NC_017063|180659:185646|184668_185646_+|WP_041201695.1|transposase|DBSCAN-SWA
MSYPKFKKKREFQGSFYIGGDQIKIIQTANTDYLKIPNLPPIKLTEKLRFQGKIHNATITQKGDHFYASISCGIDESEYKRTHKLQESHNKLGIDIGIKSFVSLSNGLNIYAPKPLDKLTRRLVRISRQLSKKIHPKTKGDKTKKSNNYLKHSKKLTHLHEKIANIRLDFLHKLTSSLIRHSNSFCLESLKVKNMFKNHRLAKSLSDVSMSVFNTLLEYKARYSNKEILRADTYYPSSKTCSNCQKVKQDLKLKDRIYQCLECGFELDRDINAAINLLKHLVGRVTAEFTPMDLTALLNDLSNNRLATSKVELGIQQKSQIERIL
>NC_017063|180659:185646|183230_184559_+|WP_000867426.1|transposase|DBSCAN-SWA
MKVNKGFKFRLYPTKEQQDKLQHCFFVYNQAYNIGLNLLQEQYETNKDLPPKERKWKRSSELDKAIKHHLNARGLSFSSVIAQQSRMNVERALKDAFKVKNRGFPKFKNSKSAKQSFLWNNQGFSIKESDEERFKTFTLMKMPLLMRMHRDFPPNFKVKQISISCSHRKYFVSFSVEYEQDITPIKNPKDCVGLDLNILDIACSCGINNHEKLTDFKQYQTDMKELLGIEIDKELDTKRLIPTYSKLYSLKKYSKKFKRLQRKQSRRVLKSKQNKTKLGGNFYKTQKKLNQAFDKSSHQKTDRYHKITSELSKQFELIVVEDLQVKNMTKRAKLKNVKQKSGLNQSINNTSFYQIISFLDYKQQHNGKLLVKVPPQYTSKTCHCCGNINHKLKLNHRQYWCLECGYREHRDINAANNILSKGLSLFGVGNIHADFKEQSLSC
>NC_017063|180659:185646|182777_183194_-|WP_014419493.1|transposase|DBSCAN-SWA
MKKIDDMRHGRHCVFLMHVHLVFVTKYRRSAFNKEVIDFLGSVFAKVCKDFESELVEFDGESDHVYLLINYPPKVSVSKLVNSLKGVSSRLTRQHHFKSVEASLWGKHLWSPSYFAGSCGGAPLEMIKQYIQEQETPH
>NC_017063|180659:185646|180659_181904_+|WP_000049816.1|DBSCAN-SWA
MSKYNCIDLFSGAGGLSLGFANTNRFNILAHIEWEKPMVATLRNALNKRFKISEKETKKRVIKFDIQKTDELINGSWSDETLKIYGSDNDESVSQFGLNGVISGKKIDVIFGGPPCQAYSLVGRVQDKHSMKYDYRNYLFESFVKIVDYYQPQCFVFENVPGMLSAKPGNQFVKDRIYESFSKIGYEIKKPNEMKEIIYSSDDHEVPQTRKRVVVFGVRKDNKEWLFKFYQNLDNLKSKNPPLSVKDAIGHLPKFRPLKTPLKINNKNISHELIGTNNLTQNFPRYNNLRDLKAMKFWIENNMNNASAKEKLDFYTKITGKVSNHNKYRNLEWDKPSPTLVVHLQKDGFMFIHPEANQSRSITIREAAILQTFPNDFEFIGSQAACFKMIGNAVPVNFAKNIALAVAKVLDEKN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000049816.1|180659_181904_+	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	1.3e-28	29.2
WP_000753490.1|181890_182169_+	hypothetical protein	A0A2I7S4C5	Vibrio_phage	2.1e-22	58.1
WP_001121191.1|182187_182655_+	hypothetical protein	S0A2X1	Cellulophaga_phage	9.2e-31	54.5
WP_014419493.1|182777_183194_-|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.5e-74	96.4
WP_000867426.1|183230_184559_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.9e-190	94.1
WP_041201695.1|184668_185646_+|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RGV0	Helicobacter_phage	4.2e-179	98.2

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_017063|1514966:1525917|DBSCAN-SWA
ACTACCCTTTTAATTCATTCCAACGCTTAGCCACAAACGCGCTCGTTTCTAACGGCACCCTCAAAGGATACACTTCATCATTGAGAATGCGCTGGATTTCTTGCTGCAACTCTGGGGCGTTTTTTTCTTCAATCTCAAAAATCAATTCGTCATGCACTTGCAAAAGCAGCCTCACCGAAGGGTTATTTTTGAAACGCTCACTCACTTTGAGCATGCCTAATTTCAATAAATCACTCGCGCTCCCTTGAAAAATCGCATTCACGCCCTCTCGCAAATAATTGCCCTTAACATAGTCATTCACTCCATTAAAATCAAACACCCGATAACGCCCAAGCAAAGTAAAGGCTTTAGAAGTTTTTAAAATCTCTTCTTTCATGCGGTTTAAATAATCTTTAATGCTAGGGAATCGTTTGAAATACGCTTCTATGTAGCTTTTAGCTTCATTTAAAGAGATGTTTAAAGTTTCGCTCAATTTCTTACTCCCCATGCCATACACCAGCCCAAAATTAATGCTTTTAGCGATGGATCGTTTTTCTTTGGCCAAATCTCCACCAAACAACGCCTTAGAAGTTTCTAAATGGATGTCTCGCCCCTTTAAAAACGCCTCCATTAAATCCTTATCCTGGCTGAAATGGGCCAATAAGCGCAATTCAATCTGCGAATAATCCACCCCTAGCAAGCAATATTCTTTAGAGCTAGCGATAAAGCCCTTACGAATGAGTAAGCCCTTAGGCGATCGCACCGGGATATTTTGCAAATTAGGCGAATGCGAGCTTAAACGCCCAGTAGCTGTGCCGGTTTGGATGAAAGTGGTATGGATTTTATCGTCTTTGTCTTTTAGGCGCAATAAGGGGGTGGTATAAGTGTTAAAAAGCTTATTCAATTCTCTGTATTCTAAAATCAAAGGGATGCTTGGGTGCTTATCTAGGATTTTTAACAAATTTTTTTCATCGGTAGAATGGCTTTTATTTTTAGGAAGCCCTAATTTTTCATACAAAATCTCGCTGAGTTGTTTGGGCGAATTGAGGTTAAAATCCACGCCGATTAGATCCAAAATTTGGCGCTCTAAAACTTTTAATTCATCTTTAAACTCCTGTTCTAATCGCTTGAAATAAGGCGCATCAATCTTAAAGCCTTGAAATTCCATATTGATTAAAACTTTCACAAACGGCGTCTCAACTTCTCTAGCCAAAGCAAGCAAGTTTTCTTCCAATCCCCCTTTTTCAAAATATTCGCACAAACGCTTTAAAGCGTGTAATTCCATATCCAATTGCTCTAATTTTTCCACCTTACTTTTAGTCTTAAAATCTTTGATTTTTTCATGCGGAATCAATTCTTCTTTTAAATATTCCTTTAAAACTTCATCAAACCCCACTTTTTCCGGATTTTTCAAAAACGCTAAAATTTGAGTGTCTTGGATGCGAATGTTTTCTAAAGACACCTGGTATTTGGCTTTTAAAAAGCTCAACAAGGGCTTTAAATCATGCCCAATGATTTGCGCATGCTGTAACATTTGAGAAAAAGCGTTTTGCAAAAATTCTAAAGAAAAGGGCGAAAATAACGCCTCTTCTAAAGGTAAAAAATAGCCTTGATCTTGTAATAAAAACGCTAGGGCCAAAACTTTTTTTTCTTTATTTAGCACCAAACGCGCAAAAACCCTAGCGTTAGGATTTTCTAACTTTTCTAAAAACGCGCTCAAAGGCTCAGCACTTTCTAAAACGATCATGCGCGATTTTTTAGGGGCGTTTTCTAAGGCGGAGGCGTTGTCTAATGTTGGTGCGTTTTCTACAATGAAAGGCGTAGGGGAATTTTCTAAATCCCTTAAGGTAGAAATAAAACCATATTCTTTCAATTCATCTTTAATTTTCAATAAGGGGTTTTCGCTAGGAAAAGCGCAACTTAAAAAATCAAATTCCTTAATACACCCTCTTTCTAAAGTGGCTAATTCTTTGCTTAAAAACGCACTTCCTTTGTCTTGTATCAAGGCTTGATACATTTTAGGGCTGAGTAAATTTTTCGCCAAGTCTAAATTTTCATAGATTTTTTCCAAACTCCCCAATTGCTGTAACAATTCCTTAGCGTTCTTGCTCCCAATGCCTTTAACCCCCTTGTAATTATCGCTGCTATCCCCCACAATGCCCTGATAATCCGTGAATTGACTCGGTAAAATCCCGTATTTTTCCACGCAATCTTGCACCAAAAACTCCGTTTTGCCATCAAAAAGCGCGATCTTATCGCTCAAAAGCTGGTTAAAATCCTTATCTTTAGAATAAATGCGGGTTTTATAAGGGCTTAGCGTGGCCAGGCTTGCGATCACGTCATCGGCTTCAAACCCATTCACCTCCACGCAAGTAAAACCCATTTTTTGCAACCATTCTAAGGCGATAGGGATTTGTAAAAGCATCTCTTTAGGGGCGTCTTTACGATTTTGTTTGTATTCGCCTAATTTTTCAGATCTTTTAGTTTTAGTCTGGCTTTCTAGAGCGAACACGATAAAAGGCATGTTTTTTCTGTCTTTATAAAATTTTTTAACCATGCCCACAAGCCCCGTTAAAAGCCCTGTAGGAAAGCCCTTATCGTTGGTTAAAGGCTTATTTTTAGCGCTCATGTAATAGCTTCTAAACAAATACGCAAAAGTATCAATTAACGCTAAAGTCCCCTCTTTAAGCTCTTCCATGCATCAACCCTCTTCAATCAAGCAAATTTTAAGTTTATTGTAACACAAGCTTGACCTCATCTCTTTCAAAATAACGAGTCTTTTTGGGTTGGCGTTTCTTGGCTGATAATCTCTTTTGTAGCCTGTATTTTAGCGCTGCTGTATTGAACCACGCCTTGAATGGTTTGTTTCATTAGAGCGTTTATAAAGGTGTGCATGAAATGAAAATCTATTTTGCCATGTTGGTTGGTGGGGAGAAAAATTAACTCATTCTCTACTTTATTAGCCCATGTCGATAAATTATCTCGTGAATATTTTGGGTATAAAACTTTTTCAATCGCTGTTTTTATAAATAAGTTACATAAAAAATTAGGGTTACCATTTTTAAATTTTATAAAATAGCTTTCAGCTAAAATCCCTACCTCATCTCTATGGGCATAAGTTAATCCTGTAGCAATTACGCCATTATAGATAATAGAAATGATATTATTATAGGTTTCAAAATCACCTTTTTTACCCCAATACATAATGCCATTATTCCCCTTTTTACAATAAACTAGGGGGATATTATGCGTGTCTGTAATGCTTTTTGAAGTTGCCTTAAATTTATCCCCCTTACCTAAAAATCTTGCACTCACTTTTTCAAACAAATCCCCCAATCTGAAGCTTTGCCATGTTAAGCCGCATGGGGTATTACCCCCCCCAGAATTTTTGCCATTGAAAAGGTTAAGGGCGTTTTCTTCATCGTTAGAAAGGGTGGTGTTTTCTAGCCCTGTAGCTTTTAAATAAGCCTCAAGTTCGGCGAGCCGACACTGCTCAAGTTCGGCGAGCCGACACTGCTCAAGTTCGGCTATAAATTTTTCCATGAAATCAAAATCAATATCCTTAAGGGTTTGAGCGTTAGCGGTGGGTTTTAGGGGTAGAATGACCTTATCGTTTTTAATTTTTACCCATGAACACATGTTTTCATAGCCGAATTTTTTAGGGTAACCAAAAAATAGCGTGGATAAAAACAAGCCGATTTTATGGTTAATTTCAAATTTAGGTTTGAGAGAAAATACCCTAGCGTGTGTTACCATTTTATAAGGAAAACTGCGATAAAATGTGCAACCAAACATGTCAATAGTGATAGTATGGCTTTCAAAAACTTTTGCTTTTATATCGCTTTGCCCTAAAACGCCATTATTGCTAAGCCCTGCGGTGATGACAAATTCGCCCTTATGATTGATATGGCGTTTTTGAATGTCAAAATCGCCGTTACTCGCTTCAAACAAATCCCCTAATCTGAACTCGCCCCACTTAATAGCGTTGAGTTGGCTACTAAGGGGGCCAATCACTTTGGGGGCGTTTGGTTTTTTAAAATCAATCCCACTTCATAAGAAAGGTAATCGGCTATCGTTCTTTTAAAATCCTCTAATTCGGGTTTAGTCTCATTCTTTTGGTGGGCTTCAAAATTAAAGTCTTTAGCATGCTTGTTTTCGCGTGGCTTAGCGATAAAATCTTCAATATAGATCGTTTCTAAATCGCCCCACAGCTCTTTAGAAACTTGAGCGTTTAAGCCGGCTTTGTAAATTTTAATGATTTCTTCGTAGCGTTTGGTGGGGTTAGAGGTTTCATTCAAGCCTCTTTTGGTGCGTTTGAAGCCATCGTTTCTAAAGTCTATGAATTTAACGGGCTTTTCATAATCGTGCGGCTCATGAGCTTTAAAAATATAAACGCTCGTTTGCACCCCGGCTTGAGGCATGAATAAATCGGTGGGCATTTTAACGCTCGCTAAAAGCGAATGCTTTTTTAAAATTTCAACATTGGATTTTAACGCTTGCCCGCTCCCTGCGCTATCTTGGATAATGATCGCTCCTAAACCGCCCTTTTGCATGTGCTCTAACCCAAACTTGATAAAAGGCATGCCGTTTTCTTCGTAGCTAAAAGGAGGGTTTAATAAAAGGATATTGGGCTTAAAATCTTCATAAATCTTTTTACTGGTTTCAAAAGTGTTGCCTTTGATGATTAAACTTGATCCATCGCCTCTTAAAATCATGTTAGTGGTGGCTAGAGAGAACATTTCAGCGTTAAGCTCCACGCCTAAAAGTTGCGTGGTTTTCATGCTTTTGATTTTTTCATTCGCTATAGTGGTGTTTTTACCATAGGTTTTTTCAATGTCTTCAATCATTAGCACCATAGAAGAAATTAAAAAGCCGGCACTCCCTGCGGCCAAATCCATCACAAAGGATTTCGCGTTAACCCCTAAAAGCTCGCTCATCATTTTAGTTACATAAGGCGGGGTTAAAACAATGCCCAATTCCTTACCATCCCCTAAAGCGTATTTTAAAAATTCGCTATAAAGTTCGCCCATGATGTCTAAATGACCGGTATTGTCGCTTTCATTAATGGGCTTATGGACAAACTCATAAAGAAAGGTAAAAATTTGCTTGGTGATGCTTGAATCTTTTTCTAAAAGCATGCTTATGGCTTTATCCAGGCTCGTTATTTTATCGTGCTGCGGATCTTTTCTGATTTCTTTAAAACTCTCAAGCATCAGATCTCGTTTTTCTTCGCTCAAGTTTTTGGTTTTTAAAAATTCGCTGATTTGGTTAAACACTAAAACGCCATCACGGCTAGTGTCGGTTATTTCGCCTTTTAAATCACTTGGTTTTAAGCCCCCTTTTTTGCCCTTAATTTCTTGCATGGATAAAAGCATGCCGCTCACATATAGCACGCGCTGAGGCGCTGTGATGTTGTGGTTATGCATCAGGCGGTTGAGTTTTTTAGCGGTTTCGTTTAGATCGGCTTTGGTTTTGATTAAGATGAGGTGCTTTTCTTCTTCAGTGAGCGTGCATTCTTTATAAAAAGCGTTAAACGATTCTTGATTTTCTAAAAAATGCAAGTTTTTAGCGTTAGTGAGCTTGTGCGAATTGATCCCGCTCGCAAAAACGTAATACACTTCTATCAAAAGGTTTTCTTCATCATCGCCGGCGATGCCTATGGCGATACATTCTTTATATTTTTCTTTGTTTCTTAAGATGTTTTGAGCGTAGTGTAAAGCCCCATTCACGGCGAATTTTGAAATGGAATGATCATCGTTTGCAAGCGCGCTGTTTTTGAGCTTTTTCAAATTTTTAGCGTAGAGTTTGTTTTCTATGATTACAGGGATAACGCTTCCTTTATTTTTTGGGTGCGTGTATTTTTCTAAGCTAAAATCTGGCTCGCCATAAGAAGTTTTATCTTTAGTTTTACTCGCATTCAAAAGGGCGTTTTTAAGACTAGGACTCATTTGGCTTTTAACATTAAAATCCGTATTTTTCATAAGCCCTAAATTGGTCAATTCTTTTTTGACATAGTCATCAACATCATCTTCTAACCGAAAAGCTAGCATATTTTTATCCTTTTTAAAAAACAAAATTATAACTCATTCATCCGCGCTGCAAAGCGCGATCGCAAAGTGCACTTTTGTGTTTAGAGTTTTAAGGTATTTTAGGGCTTCTTTTAGGGTGGTGCCGGTGGTGATAATATCATCTAATAAAAAATAATCTAAATTCTCATCGCCCCTGAAAGTGAAATCCCGTGGGTTGTTGGCGCGAAATTCTAAGCTTTTACCGGCATATGAAACAGCATTAGTCGCCCTTAAAGTCCCATAAGTGGGTTTTAAATTGCCTTGGCAAAAGCCTTTTAAAAGCACGGCTGAATGCGAGTAAAAGGATTTGATTTTATCATCAACGGCGATGCCATAAAGGGGGATATTCAAGCCTTGTTCTTGTAAGATTTTCACAAATTCCGCACCGGCTTTTTGAGAAAGCAAGGGCAAAATGCGAGATCCAATCAGCGCGTATTTGCTTTTAATGAGCTCTCCTATCTCGCTATAAGCGTAAAAACTATACACGCTCACGCCCTCTAAAACCCTTACCTTTAAGCTTAAGGGCAGATCGTTTAGGCAATTTGGGCAAAGAGGCTTAAAAGAAAGCTTCAAACAAGTTAAACAACGCATTTTATAAAGGCGGTGATTTGCTCGTGTAAGTTTTTAACGCTTTCTTTAGCGTTTAGTTCCAAAACTTCGCACCCGAATTTTTCTCTTAACGCGTAAGCGTGGGTTTTGAGCTTTTGCTGGATATGAAGTAATTTTTCTATGCCTTGGTTTTCTATTTTGTCTAAACTTTTAAGGCTTAAGCGCTGTTTTAAACCCTCTTCATCTATCACTAAAAGAACGATTTTTGTAGGCAAGACGCTTTGAGTGGCAAGCAGGTTTAATTCCAAGCTTGAAAATGCGCTATAAGCCATGCCAGAGATTAAACTCCTGTCGCTAATGATGAGTCTTTTTTCTTTCAATGCCGGTTTGATCACGCTTTCTATATGCTCAGCCCTATCGCTTAAGAATAAAAACGCTCGGGCTAATTCGCTGATATTTTCATTTAAAGCGATACGCCTTAAACTCTCGCCCATTCTCGTCCCCCCTGGCTCTTTGGTAAAAAGGGCGTTTTTAAACCTGTCTTTTAATAATTCTACTTGAGTGCTTTTGCCCGCGCCATCAACGCCTTCTAACACCACATACATTTTTTAAACCTTTGAAATCAAAGGATAAATTTCTTTAGGCACTAAATGGCTCGCATCGCCCTTATGTGCGATAATGGATCGCACGATAGAAGAGCTTATGAAAGCGTTTTGTAAAGTGGGCATGAAATACAAGGTTTCTAATTCGTGGTTTAAGGATTTGTTCGCATAGCCCATTTGCAATTCGTATTCAAAATCGCTCACCACCCTTAAGCCCCTAACCAACACCTTACAATGATACTCTTTAGCCAGATTGGCTAATAGCCCTTCAAACGCCACGCATTCTACATTTTTAAAACCTTTAGTGGCCAGTTGCATCATTTTTAAGCGTTCATCTAAACTAAACATGGGGTTTTTAGCGCTTGAATGCGCCACAGCGACAATGAGCTTTTCAAACAATTCGCTGGATCGATGAATAATGTCTATATGCCCATTCGTTACCGGATCAAAAGTGCCCGGGTAAATGCCGATTTTTTGCATCAGTTCATTCCCCATCGTGGGTATAAGTCATTTTCTATCCCTAAGCTGTCAAACCACTTCCCCACTAAAAAATCTTGCATCGCTTCTAAAGTCTTGCTCTGGGTGTAATAAGTCATCATCGGCGGCGCAATGATTGCATTAGAATGGGCGAGTTTGAGCAAATTTTCTAACATGATAGCGCTTAAAGGCATTTCTCTAGGGGCAATGAGTAAGGGGCGCTTTTCTTTAAGCATCACAGACGCACTCCTAGAAATCAAATCCCCCCCAAAGCCATGCGCGATTTTAGCCACCATGTCCATACTCGCTGGAATGATCGCCATTTTATGGATACCATAACTCCCTGAAGCGATGCTCGCATGGATGTCTTGCTCATTAAAAAAAGTCGCGCTAGGCCGTAAATCTTTCATGGCGTTTTTAAGGTTGATATTAGATTCTTCTAACGCCACGACATGCGCGTTTTTAGACGCCACGACAAAAACTTCAATTTCTTTGGGTAATTTTTCTAAAAACCGCAAGGCTAGGGGTATCCCGCTCGCCCCGCTGATGCCTAAAACTAATTTCATGAATATCCTTTATAAGATTTGCGCTTTAGAGCCACTCAACACTTTTGCTTTTAAGATTTTATTGCTTTCTAAATTTTTGGCTTGAATGATTTGATTAAGCGCGCCATTTTCTAGGGCTTTTAGGCTTATTTCTATGCTGATTTGCCCCTCTTCATACACCCCGGTAATAATGTCGTTTTTACGCACGATGATTAAGGCTTGGGTTTTATCTGTGCTTAAAAGCGTGTTAGGGGGGATAAAATTTTTCGCGCTCACTTTATCAATCGCGCCCTCTAATAAGGGGTTAGAAAGCGTGCCAAAAGGAATGCGCTCTTTTTGAGTGTTGTTAGCGGTGATGTTCTCGTCTTTTTTAATCGCGCTAGCGCTTTTAAAAGCCTGCATGCTGCCTATCACGCTATAACGCACCGGCAAGCGTAAATTAGGCTCATTTTCCAACCTTAAAAACACGACCCCATCTTTTTTAAGCTTGTTAGAAGCATTCAATTCATAGCTTAAAATGGAAGCGTGAGAAAAACGCTCTGGGATTTCTAAGTTAATGGTTTCAATTTCTAATTTTAAGTCTTTGTATTCTTTGAGGTAAGTTTCTTTGATCTCTGTTTTAAGCGCGTTCAAATCTAGGGCGAACAATGCGTTTAAACCTATCAAAAAAAGGGTTAAAATTTTCAAAACCCGTTATCCACTTTTTCTACAAATTTTTCTGAGATTTTATCATAGACATTCCCTCCGCAATTGATTTTCAAGCACAAACCGCTCAAGCCTTTTTCTACGCCTAAAACCCTACCGGTGCCAAAAATCTTATGTTTGATCAAATCCCCCACTTTAATGGGTGCGTCTTTTTGGTGATTTTGTTTAGGAGTTTGATCGCTTTTGAGCAACTGGGCTTCTTCTAAAAACACAGAGGGCGAGCAAGAAATTTTCCTCCCGAAATACGAACGCTCTTTGACATAAGAGAGCTGCAATCCTTCTTTAGCCCTAGTGATTGCCACATAAGCCAAGCGCCTTTCTTCTTCCAAATCGCTTTCTTGATTGAACCCCCTATGCGGGAAAAACCCTTCTTCTAACCCGATCACAAACACATGCTTAAACTCTAACCCCTTACTCATATGCACGCTCATGCAACTCACTTTTTGCGCGTTTTCTGTATTATGGACATCCAACACGCTTTCATTCAAAAAATCCAGTAAAGAATGCGTGGGGTTAGTTTTAAAATGCTCTTTCACTAAACTTAAAAGCTCTTTAACAAAGCCCTCTCTTTCTTCGTAATTGTCTTCTTTTTCATAGCTTTTTAAAAGGTTAGTTTCTTCTAAAAACCGCTCGCAAAACTCCTCTACTGAAATTTCAAAAGCCTCCCTCAAACGCCCTATTATAGCGATGAATTTATTCAAGGCGTATTCGTTTTTAGGGTTTAATTTGTCTTTAAACGCCCCAAGTTTTAACGCTTCTTCTAAATTCAAACCCTCCTCATCTAAAAGAGAAAAAATCCATTCTTGAGTGATCTTGCCAAGGCCTCTTGGGGGCTTGTTTAAAACGCGCTTGATAAAAAAGCGATCGTCTTTTTTCGCCACTAAATGCATGAACGCCAAAGCGTCTTTAACCTCAGCTCTTTCATAGAAACTCAGCGCCCCAATAAGCCTATAAGGGATATTCAAAGCGTTCAAGCTCTCTTCAATGCTGCGGCTAAGCCCGTTTAAGCGGTACAAAATAGCGATATTTTCTAAATTTTCGCCTTTCTTTAAAAGGGCTTTGATCTGATAAGCCACATCTAAGCTCTCTTCTTTTTGCGTGGGGTATTCTTTACAAACCACGCTTTTATGCGAGCCTTTGAAACTTTGAAGCGTTTTAATGTGGCGGTGTTGGTTATGGCTAATCAAAGAATTAGCGCACGCTAAGATTTCAGCGCTGGAGCGATAATTGGTCTCTAATTTCACTATTTTAGCCCCTTTAAAATGCTTGGAAAAATTTAAAATGTTAGAAATATCCGCCCCCCTAAAACCATAAATGCTCTGATCGTCATCGCCCACCACGCACAAATTATGGTGCGTGCAACTCAATTGTTTTAAAAATTCCAGTTGCAGGGCATTCGTGTCTTGGTATTCATCTACCATAATATAATGGTAGCGTTCGCTAATCTCTTTGGCGAGTTTTTCATTATCTTGTAAAATCTTAAGGCTCAAACAAAGCAAATCGTCAAAATCCACTAAATTGTCTTTTTTGAGCGCGTTTTGATAAAGCTCATACGCTTTATAGCATTCGCTATCTTGCGTGCTTAAATCCATCATGCCGTTTTTGATTTGAGAAATATTGACTCTGAAGTTTGAAATTTTGAGCTGCTTGCACAGCGTTTTGACTTCATCGCTATCTAGCACCGAAAAATCGCACGCTCTTTTTAAAAGGCTCATGTGTTGCCTTAAAAACAGCAAACCAAAACGATGGAAAGTGCAAAGCAAGGGGGGGATAAACGCTTGATTTTCCAACAATTTCAAAGCCCTTTCTTGCATTTCTCTACTCGCTTTATTGGTGAAAGTGAGCGTTAAAGTGTTCTCGCTAGGCACGCCACAAACGCCAATCAAATACGCTAAACGGCTCGTTAAAGTCTTAGTCTTACCGCTCCCAGCTCCCGCTAAAATCAATAAAGGCCCTTGAATGTGGCTTGCAGCGATTTTTTGCGCTCCGTTCAAATTGTCTAAAATGCTTTTTTCAAAACCCATTAT

Protein sequences of DBSCAN-SWA_2

>NC_017063|1514966:1525917|1518954_1520994_-|WP_000879239.1|DBSCAN-SWA
MLAFRLEDDVDDYVKKELTNLGLMKNTDFNVKSQMSPSLKNALLNASKTKDKTSYGEPDFSLEKYTHPKNKGSVIPVIIENKLYAKNLKKLKNSALANDDHSISKFAVNGALHYAQNILRNKEKYKECIAIGIAGDDEENLLIEVYYVFASGINSHKLTNAKNLHFLENQESFNAFYKECTLTEEEKHLILIKTKADLNETAKKLNRLMHNHNITAPQRVLYVSGMLLSMQEIKGKKGGLKPSDLKGEITDTSRDGVLVFNQISEFLKTKNLSEEKRDLMLESFKEIRKDPQHDKITSLDKAISMLLEKDSSITKQIFTFLYEFVHKPINESDNTGHLDIMGELYSEFLKYALGDGKELGIVLTPPYVTKMMSELLGVNAKSFVMDLAAGSAGFLISSMVLMIEDIEKTYGKNTTIANEKIKSMKTTQLLGVELNAEMFSLATTNMILRGDGSSLIIKGNTFETSKKIYEDFKPNILLLNPPFSYEENGMPFIKFGLEHMQKGGLGAIIIQDSAGSGQALKSNVEILKKHSLLASVKMPTDLFMPQAGVQTSVYIFKAHEPHDYEKPVKFIDFRNDGFKRTKRGLNETSNPTKRYEEIIKIYKAGLNAQVSKELWGDLETIYIEDFIAKPRENKHAKDFNFEAHQKNETKPELEDFKRTIADYLSYEVGLILKNQTPPK
>NC_017063|1514966:1525917|1523868_1525917_-|WP_080012223.1|DBSCAN-SWA
MMGFEKSILDNLNGAQKIAASHIQGPLLILAGAGSGKTKTLTSRLAYLIGVCGVPSENTLTLTFTNKASREMQERALKLLENQAFIPPLLCTFHRFGLLFLRQHMSLLKRACDFSVLDSDEVKTLCKQLKISNFRVNISQIKNGMMDLSTQDSECYKAYELYQNALKKDNLVDFDDLLCLSLKILQDNEKLAKEISERYHYIMVDEYQDTNALQLEFLKQLSCTHHNLCVVGDDDQSIYGFRGADISNILNFSKHFKGAKIVKLETNYRSSAEILACANSLISHNQHRHIKTLQSFKGSHKSVVCKEYPTQKEESLDVAYQIKALLKKGENLENIAILYRLNGLSRSIEESLNALNIPYRLIGALSFYERAEVKDALAFMHLVAKKDDRFFIKRVLNKPPRGLGKITQEWIFSLLDEEGLNLEEALKLGAFKDKLNPKNEYALNKFIAIIGRLREAFEISVEEFCERFLEETNLLKSYEKEDNYEEREGFVKELLSLVKEHFKTNPTHSLLDFLNESVLDVHNTENAQKVSCMSVHMSKGLEFKHVFVIGLEEGFFPHRGFNQESDLEEERRLAYVAITRAKEGLQLSYVKERSYFGRKISCSPSVFLEEAQLLKSDQTPKQNHQKDAPIKVGDLIKHKIFGTGRVLGVEKGLSGLCLKINCGGNVYDKISEKFVEKVDNGF
>NC_017063|1514966:1525917|1517707_1518958_-|WP_000580121.1|DBSCAN-SWA
MIGPLSSQLNAIKWGEFRLGDLFEASNGDFDIQKRHINHKGEFVITAGLSNNGVLGQSDIKAKVFESHTITIDMFGCTFYRSFPYKMVTHARVFSLKPKFEINHKIGLFLSTLFFGYPKKFGYENMCSWVKIKNDKVILPLKPTANAQTLKDIDFDFMEKFIAELEQCRLAELEQCRLAELEAYLKATGLENTTLSNDEENALNLFNGKNSGGGNTPCGLTWQSFRLGDLFEKVSARFLGKGDKFKATSKSITDTHNIPLVYCKKGNNGIMYWGKKGDFETYNNIISIIYNGVIATGLTYAHRDEVGILAESYFIKFKNGNPNFLCNLFIKTAIEKVLYPKYSRDNLSTWANKVENELIFLPTNQHGKIDFHFMHTFINALMKQTIQGVVQYSSAKIQATKEIISQETPTQKDSLF
>NC_017063|1514966:1525917|1514966_1517642_-|WP_000391834.1|DBSCAN-SWA
MEELKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRKNMPFIVFALESQTKTKRSEKLGEYKQNRKDAPKEMLLQIPIALEWLQKMGFTCVEVNGFEADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKTEFLVQDCVEKYGILPSQFTDYQGIVGDSSDNYKGVKGIGSKNAKELLQQLGSLEKIYENLDLAKNLLSPKMYQALIQDKGSAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPTPFIVENAPTLDNASALENAPKKSRMIVLESAEPLSAFLEKLENPNARVFARLVLNKEKKVLALAFLLQDQGYFLPLEEALFSPFSLEFLQNAFSQMLQHAQIIGHDLKPLLSFLKAKYQVSLENIRIQDTQILAFLKNPEKVGFDEVLKEYLKEELIPHEKIKDFKTKSKVEKLEQLDMELHALKRLCEYFEKGGLEENLLALAREVETPFVKVLINMEFQGFKIDAPYFKRLEQEFKDELKVLERQILDLIGVDFNLNSPKQLSEILYEKLGLPKNKSHSTDEKNLLKILDKHPSIPLILEYRELNKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSPNLQNIPVRSPKGLLIRKGFIASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGGDLAKEKRSIAKSINFGLVYGMGSKKLSETLNISLNEAKSYIEAYFKRFPSIKDYLNRMKEEILKTSKAFTLLGRYRVFDFNGVNDYVKGNYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLLQVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETSAFVAKRWNELKG
>NC_017063|1514966:1525917|1523215_1523872_-|WP_000699042.1|DBSCAN-SWA
MKILTLFLIGLNALFALDLNALKTEIKETYLKEYKDLKLEIETINLEIPERFSHASILSYELNASNKLKKDGVVFLRLENEPNLRLPVRYSVIGSMQAFKSASAIKKDENITANNTQKERIPFGTLSNPLLEGAIDKVSAKNFIPPNTLLSTDKTQALIIVRKNDIITGVYEEGQISIEISLKALENGALNQIIQAKNLESNKILKAKVLSGSKAQIL
>NC_017063|1514966:1525917|1522642_1523206_-|WP_000780111.1|DBSCAN-SWA
MKLVLGISGASGIPLALRFLEKLPKEIEVFVVASKNAHVVALEESNINLKNAMKDLRPSATFFNEQDIHASIASGSYGIHKMAIIPASMDMVAKIAHGFGGDLISRSASVMLKEKRPLLIAPREMPLSAIMLENLLKLAHSNAIIAPPMMTYYTQSKTLEAMQDFLVGKWFDSLGIENDLYPRWGMN
>NC_017063|1514966:1525917|1522169_1522643_-|WP_001169236.1|DBSCAN-SWA
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMMQLATKGFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKV
>NC_017063|1514966:1525917|1521027_1521603_-|WP_001203612.1|DBSCAN-SWA
MRCLTCLKLSFKPLCPNCLNDLPLSLKVRVLEGVSVYSFYAYSEIGELIKSKYALIGSRILPLLSQKAGAEFVKILQEQGLNIPLYGIAVDDKIKSFYSHSAVLLKGFCQGNLKPTYGTLRATNAVSYAGKSLEFRANNPRDFTFRGDENLDYFLLDDIITTGTTLKEALKYLKTLNTKVHFAIALCSADE
>NC_017063|1514966:1525917|1521590_1522166_-|WP_000289697.1|DBSCAN-SWA
MYVVLEGVDGAGKSTQVELLKDRFKNALFTKEPGGTRMGESLRRIALNENISELARAFLFLSDRAEHIESVIKPALKEKRLIISDRSLISGMAYSAFSSLELNLLATQSVLPTKIVLLVIDEEGLKQRLSLKSLDKIENQGIEKLLHIQQKLKTHAYALREKFGCEVLELNAKESVKNLHEQITAFIKCVV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000391834.1|1514966_1517642_-	DNA polymerase I	A0A218MKQ4	uncultured_virus	2.1e-58	30.0
WP_000580121.1|1517707_1518958_-	type II restriction endonuclease	A0A2H4J4K4	uncultured_Caudovirales_phage	7.2e-06	34.4
WP_000879239.1|1518954_1520994_-	N-6 DNA methylase	A0A2H4JBT5	uncultured_Caudovirales_phage	3.0e-211	57.8
WP_001203612.1|1521027_1521603_-	ComF family protein	NA	NA	NA	NA
WP_000289697.1|1521590_1522166_-	dTMP kinase	Q2XUX0	environmental_halophage	3.4e-11	38.3
WP_001169236.1|1522169_1522643_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	4.3e-28	44.9
WP_000780111.1|1522642_1523206_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_000699042.1|1523215_1523872_-	flagellar basal body P-ring formation protein FlgA	NA	NA	NA	NA
WP_080012223.1|1523868_1525917_-	DNA helicase UvrD	A7KV33	Bacillus_phage	9.8e-93	35.1