CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017672	Paenibacillus mucilaginosus K02, complete sequence	17 crisprs	WYL,cas3,csa3,DEDDh,RT,DinG	2	10	5	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_017672_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_1

1496945-1497046

Orphan

Consensus_repeat	Method
AGCGACCTTTGTGCGAAGCACACGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_1

>merge|NC_017672|1|1496945-1497046|CRISPRCasFinder
AGCGACCTTTGTGCGAAGCACACGGGAGCGTAAAAAGATTCGAGCTTCCCCTACCAGCGAGGATCTATCTTTTTGATAGCGACCTTTGTGCGAAGCACAACG

>NC_017672|1|1|1496945-1497046|CRISPRCasFinder
AGCGACCTTTGTGCGAAGCACACGG	GAGCGTAAAAAGATTCGAGCTTCCCCTACCAGCGAGGATCTATCTTTTTGAT
AGCGACCTTTGTGCGAAGCACAACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014649732.1\|1497080_1498730_-\|lipase	unknown	unknown	gnl\|CDD\|238859
NC_017672.3\|WP_014649731.1\|1496499_1496712_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014649733.1\|1499181_1500558_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143454
NC_017672.3\|WP_016362364.1\|1502388_1503903_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270298
NC_017672.3\|WP_014649729.1\|1491474_1492431_+\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|274464
NC_017672.3\|WP_014649740.1\|1507685_1509323_-\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NC_017672.3\|WP_014649726.1\|1488492_1489323_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133382
NC_017672.3\|WP_014649737.1\|1504354_1506001_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013917126.1\|1493869_1494319_+\|PTS-transporter-subunit-EIIA	unknown	unknown	gnl\|CDD\|273298
NC_017672.3\|WP_014368868.1\|1511411_1512461_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380532
NC_017672.3\|WP_014649728.1\|1490676_1491471_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NC_017672.3\|WP_016362758.1\|1494514_1495966_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|377531
NC_017672.3\|WP_014649727.1\|1489408_1490179_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183719
NC_017672.3\|WP_014649725.1\|1487918_1488320_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|366361
NC_017672.3\|WP_014368858.1\|1492459_1493845_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|236740
NC_017672.3\|WP_014649739.1\|1506715_1507702_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380537
NC_017672.3\|WP_014649738.1\|1506223_1506541_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014649734.1\|1500734_1501400_-\|glycoside-hydrolase-family-73-protein	unknown	unknown	gnl\|CDD\|224619
NC_017672.3\|WP_014649741.1\|1509331_1511131_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NC_017672.3\|WP_014649724.1\|1486312_1487821_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270298

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014649732.1\|1497080_1498730_-\|lipase	gnl\|CDD\|238859	cd01821, Rhamnogalacturan_acetylesterase_like, Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are highly branched regions in pectic polysaccharides, consisting of repeating -(1,2)-L-Rha-(1,4)-D-GalUA disaccharide units, with many rhamnose residues substituted by neutral oligosaccharides such as arabinans, galactans and arabinogalactans. Extracellular enzymes participating in the degradation of plant cell wall polymers, such as Rhamnogalacturonan acetylesterase, would typically be found in saprophytic and plant pathogenic fungi and bacteria.	7.6035e-92
NC_017672.3\|WP_014649740.1\|1507685_1509323_-\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	4.82356e-71
NC_017672.3\|WP_014649733.1\|1499181_1500558_+\|aldehyde-dehydrogenase	gnl\|CDD\|143454	cd07136, ALDH_YwdH-P39616, Bacillus subtilis aldehyde dehydrogenase ywdH-like. Uncharacterized Bacillus subtilis ywdH aldehyde dehydrogenase (locus P39616) most closely related to the ALDHs and fatty ALDHs of families 3 and 14, and similar sequences, are included in this CD.	0
NC_017672.3\|WP_016362364.1\|1502388_1503903_+\|extracellular-solute-binding-protein	gnl\|CDD\|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	2.1055e-108
NC_017672.3\|WP_014649729.1\|1491474_1492431_+\|1-phosphofructokinase	gnl\|CDD\|274464	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family. This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.	6.42273e-119
NC_017672.3\|WP_014649726.1\|1488492_1489323_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133382	cd01107, HTH_BmrR, Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BmrR and YdfL of Bacillus subtilis, and related proteins; N-terminal domain. Bmr is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. BmrR is comprised of two distinct domains that harbor a regulatory (effector-binding) site and an active (DNA-binding) site. The conserved N-terminal domain contains a winged HTH motif that mediates DNA binding, while the C-terminal domain binds coactivating, toxic compounds. BmrR shares the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	1.78185e-44
NC_017672.3\|WP_013917126.1\|1493869_1494319_+\|PTS-transporter-subunit-EIIA	gnl\|CDD\|273298	TIGR00848, Includes:_Phosphotransferase_enzyme_IIA_component, PTS system, fructose subfamily, IIA component. 4.A.2 The PTS Fructose-Mannitol (Fru) Family Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Fru family is a large and complex family which includes several sequenced fructose and mannitol-specific permeases as well as several putative PTS permeases of unknown specificities. The fructose permeases of this family phosphorylate fructose on the 1-position. Those of family 4.6 phosphorylate fructose on the 6-position. The Fru family PTS systems typically have 3 domains, IIA, IIB and IIC, which may be found as 1 or more proteins. The fructose and mannitol transporters form separate phylogenetic clusters in this family. This model is specific for the IIA domain of the fructose PTS transporters. Also similar to the Enzyme IIA Fru subunits of the PTS, but included in TIGR01419 rather than this model, is enzyme IIA Ntr (nitrogen), also called PtsN, found in E. coli and other organisms, which may play a solely regulatory role. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS].	2.03817e-41
NC_017672.3\|WP_014368868.1\|1511411_1512461_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380532	cd06309, PBP1_galactofuranose_YtfQ-like, periplasmic binding domain of ABC-type galactofuranose YtfQ-like transport systems. Periplasmic binding domain of ABC-type YtfQ-like transport systems. The YtfQ protein from Escherichia coli is up-regulated under glucose-limited conditions and shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their ligand specificity is not determined experimentally.	9.13637e-140
NC_017672.3\|WP_014649728.1\|1490676_1491471_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	8.31203e-95
NC_017672.3\|WP_016362758.1\|1494514_1495966_-\|IS1182-family-transposase	gnl\|CDD\|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	1.3108e-19
NC_017672.3\|WP_014649727.1\|1489408_1490179_+\|SDR-family-oxidoreductase	gnl\|CDD\|183719	PRK12747, PRK12747, short chain dehydrogenase; Provisional.	6.76595e-104
NC_017672.3\|WP_014649725.1\|1487918_1488320_+\|VOC-family-protein	gnl\|CDD\|366361	pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.	4.22743e-11
NC_017672.3\|WP_014368858.1\|1492459_1493845_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	0
NC_017672.3\|WP_014649739.1\|1506715_1507702_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380537	cd06314, PBP1_tmGBP, periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs. Periplasmic sugar-binding domain of Thermotoga maritima glucose-binding protein (tmGBP) and its close homologs from other bacteria. They are members of the type 1 periplasmic binding protein superfamily which consists of two domains connected by a three-stranded hinge. TmGBP is specific for glucose and its binding pocket is buried at the interface of the two domains. TmGBP also exhibits high thermostability and the highest structural similarity to E. coli glucose binding protein (ecGBP).	6.09498e-71
NC_017672.3\|WP_014649734.1\|1500734_1501400_-\|glycoside-hydrolase-family-73-protein	gnl\|CDD\|224619	COG1705, FlgJ, Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion].	5.5478e-51
NC_017672.3\|WP_014649741.1\|1509331_1511131_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.10233e-57
NC_017672.3\|WP_014649724.1\|1486312_1487821_+\|extracellular-solute-binding-protein	gnl\|CDD\|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	3.35087e-108

>NC_017672.3|WP_014649731.1|1496499_1496712_-|hypothetical-protein
MALKRNKRLLIGIGDPAAKAVAAYGDRCYRRTEQGALVIRYIDKQNHTTLEFWLDGATVSRVRPDSDELK
>NC_017672.3|WP_016362758.1|1494514_1495966_-|IS1182-family-transposase
MIQQQQSLVLSPYAALYDIVVPKDNMLRQINELVDFTFIFEELQTKYCLDNGRNAIDPIRMFKYLLLKAIFELSDVDIVERSKYDLSFKYFLGMAPEDPVIDPSSLTKFRKLRLKDINLLDMLIGKTVDLAIELKILKSNSIIVDATHTKARYNQKSPLEILRDRARKLRKSVYTMDESIKAKMPAKNTSDVLEDEIEYCQKLVTFIELESGIAQVPKVLNPLHLLKETVEDDIEQLRLTADPDARVGHKSADSAFFGYKTHLAMTEERIITAAVITTGEKNDGKQLQTLIEKSNAAGMQVKTVIGDTAYSEKDNILYTTNNEIELVSKLNPLITQGSRKKEEEFLFNKDAGMYVCPAGHMATRKARQGKKGVGKNQQDTYYFDVEICKSCPLKEGCYKEGAKSKTYSVTIKSDEHAEQMAFQETEYFKAKSKERYKIEAKNSELKHRHGYDVATSSGLIGIEMQGAMAIFAVNLKRILKLVD
>NC_017672.3|WP_013917126.1|1493869_1494319_+|PTS-transporter-subunit-EIIA
MNIASILRTETIELNMTAATKEEAIAKMAALVGNAGFLSDQDQYVKDVLIREGSSSTGIGFGVAIPHGKSSGVKSAALAFAKFAEPVEWASMDGQPVTMAFLIGVPVEQAGQEHLKILTTLARKLIHESFRQTLTDAASAEDVLKALDF
>NC_017672.3|WP_014368858.1|1492459_1493845_+|PTS-transporter-subunit-EIIC
MEKKILAVTACPTGIAHTYMSAEALEQAAGARGIPLKVEKRGAMGIEDGLTDEEIREAHAVIIAADTDVQEARFAGKNIVKVAVAEAIKNPNGLLDQALAKEARQASAADAIAQVEQAKQERSKQRSGLYKHLMTGVSNMLPLVVAGGLIIALSFVFGIEAFKQEGTLAAALMNIGGGAAFALMVPILSGFIAFSIADRVGLAPGLVGGMLASQLGAGFLGGIISGFLAGYIAQGLKQYLKLPKNFEGLKPILLIPLLSTLTVGLLMVYVIGSPLKAVMDGLTAWLTGMGSTNAILLGLILGAMMAFDMGGPVNKSAYTFAIGLLGSSVYAPMAAVMAAGMTAPLGLWLATMLAPKKYTKEEREAGKAASILGISFITEGAIPFAAADPLRVIPSIVAGSAVTGALSMAFNVTLKAPHGGIFVMAIPHAVEHVLFYALAIAAGMVVTAITVNLLKTNKTTA
>NC_017672.3|WP_014649729.1|1491474_1492431_+|1-phosphofructokinase
MTKSEVLTVTLNPSIDKTIVLPELRVGSLNRTSEVRLDPGGKGINVARLLHEFGVGVTAAGWSGGAEGEALMGYLKRDGIAASFTPVQGRTRTNLKIVDSSKELTTEINEAGAVVTEAELAAFIRDFTLLLENVSYLILGGSIPPGVPDTIYARLAGIAREHGVKTVLDADGEALREGLQAVPFAVKPNIHELERLLGRILASDEEIVEAARELLGQGVSIVIVSMGEAGSIAVSGEEAYRVKPFEITVKSTVGAGDSMVACLVHCLLQGKGLRDIAAWTAAAGTLTASKEGTQLCTLAEVQEHVHRVEVHSIGVHPL
>NC_017672.3|WP_014649728.1|1490676_1491471_+|DeoR/GlpR-transcriptional-regulator
MFGEERKTKIMERLEREERVDVVELSQSLEVSESTVRRDLRELEEAGLLKRTHGGAVSNKIAVKNGVNLEPSFREKEVQYQREKQAIARKAVEWIREGDTVLLDSGTTTFYILQELKAFRQLTVVTNAVISPQHLDHHPGIELIFLGGTFRAQTQSMVGMFTEQSLGLIRVDKCFIATNGVDPVQGLTTPTMAEAAIKRRMISCAQEVVLVTDSSKFGRTHFAKFGELEQIHTCITDAGIPENDIKSLHSRGITVVTVDTDRND
>NC_017672.3|WP_014649727.1|1489408_1490179_+|SDR-family-oxidoreductase
MNTGRLNGKAALVTGASRGIGRGIAERLARDGAVVAIHYGSRRDAAEEAAARIQAEGGTAFPVGADLGSLESIEAMWGQLDAKLTELTGEARLDILVNNAGIGTRGKIGETTEAMFDELMTVNVKAPFFLIQGALPRMRDGGRIINISSGVTRIAYPDLAAYNMTKGALNTLTLTLAKELGPRGITVNAILPGIVDTEMNAAWLHEPQAWKFASEMSALGRVGQPGDIADIAGFLASDDSRWVTAQMIDATGGSHL
>NC_017672.3|WP_014649726.1|1488492_1489323_+|MerR-family-transcriptional-regulator
MFKISDFSKLSRVSVKTLRYYDQIGLLRPAHTDGDSGYRYYTADQLYRLHRILAFKDLGFTLEQIGPILEEVSCEEINGMLRLKQAELQQKVLEEQARLARIEARVQQIRLEEGKAPVSEPVVKRIDAELAATLRAQVPRSHLGQLAAEAQRHVQGQGMAPGPLVVQWHDCGLPDGRVDIEVGVLLGRPIRDDGRFRVTRLPEMPLVASFLHRCDPRGVCRASSQLAQWIERNGYRIADEPPQRELFYPEAEGEDPGALRHAELLIPVVPNGSKTD
>NC_017672.3|WP_014649725.1|1487918_1488320_+|VOC-family-protein
MLTSLEHMQIPVREMDRAIKWYTEELGFGLANRDGGRTAFLTLPEGPVLMLWQTDDEATYAHYTVNGTDFPVLLYRTERIHELHDRLKESGTRIQLYRNDGFAWVLKFYDPEGNLWGVLQYNPDSDMGRQDVS
>NC_017672.3|WP_014649724.1|1486312_1487821_+|extracellular-solute-binding-protein
MGAGQRWAAGLTACCTMLLAGCSGEERGSGTESGTADRFPITIAAAQVGDALADGNDVERAIEAYTGTQLDIQWIPSAAYDDKVSVLIASGKLPMMLRLKSTPPSARAIQSGLFWEIGPYLPSYPNLSALSPQYYDNIRVDGKLYGVPLFRDIARSAVVYRKDWLEKLGMSLPVTAEQWYEVCRAMALGDPDGNGRDDTYGLILGKKYSDGSAATTTRIAVSLGAPNKWGVDEQGQFTPEFMTEPYLDVLRLLRRLYEEKLVNRDFAVLDDDEAEKQYDTGRGGLRVGVAQNAKGMQDRLTGSGIKGEYDLAPMTGPSGVRATAEPGNNGFYVFPKSSVKSEEELKKILGFIDKMLDEEMATLQLRGLEGRHFIRTEGGAAEYKDFELFQKEVKPYRDTFFNLEGYKGVPLKDTPLGEKGKRIPKESLASAVRNPAAGLESRTYTERGRELEERIGDAQTKFIMGRIDEAGWQAEVQAWLKAGGEQMIREYEEAYRKASSAR
>NC_017672.3|WP_014649732.1|1497080_1498730_-|lipase
MYKLMSSKIFKTVSAVLLAAALGAGSLPAGVPSVQAADTSLSARNQLLLDCGPGPAAPGYVRLLPSTLYKASPGYGFLNPKLVTGADRGTPDALRGDFCVPKSPLRADLPNGEYQVTVLSGDSAEASITAVTAEASITADFTAAGGQFDQKTLMVPVTDRRLDLEFGGTAPRINAIEISRVHKFDFGPGAVEPGYTPVRQTTAYSASTGYGFSDVTKVTYGADRGAPDALRGDYLGASGASFLLDLPNGDYEVSLISGDQTEANLVDIKAEGIYRARALAAAAGEFSTATFNVAVIDGQLSIEVLGAVPRLNSLVVKKRPNRVKGDKPTAYLAGDSTVQTYNSRFYPQAGWGQKIGDYFTDGVIFANRAIGGRSSRSFVNDGRLDTILNEIRPGDYLFVQFGHNDASSNPERYAAPYTTYKEYLKMYLDGAKQRGATPVLVTPVGRRSWDANGLFKNDFPDHYAAMKQVAEEQNVQLLDLNARSIAFYNTVGIEETKALFLWLEPGVYPNFPNGVQDNTHFKEEGAVQIARLVTEGIRDLQLGIAAFIK
>NC_017672.3|WP_014649733.1|1499181_1500558_+|aldehyde-dehydrogenase
MDLDRIHSVIIKQKEHFNRGETRPLAVRQAHLGALRQAVKRYEAEIIDALRADLGKSELEAYSTEIGFLLEEIRFVSKRMKGWAKPRKVKTAPTHIGSRGVIIPEPYGTALIIAPWNYPFQLALSPLVGAIAAGNTAVLKPSELTPTVSALLARLVADTFAPEVVAVIEGGVEETTELLRQPFDYIFFTGSVPVGRIVMEAAAKRLIPVTLELGGKSPCIVHRDAKLELAAKRIAFGKFANSGQTCIAPDYLLVHEEVKDELLRHLQAAVEEFYGREPVRNPDYGRIVSRRHYDRLVRFLGDGRSVFGGQSDDQALRIAPTALDGVSPEAPVMQEEIFGPILPVLTYREIGETIAAVNAKPKPLALYLFTEDAGVQREVVEKVSFGGGCINDTLMHIATPYLPFGGVGESGMGSYHGESSFKAFSHFKSVLKQTTLFDIAFRYPSAKNGLKLIRRFMK
>NC_017672.3|WP_014649734.1|1500734_1501400_-|glycoside-hydrolase-family-73-protein
MKPQEFFSLLGPAAAAEQIEHGVLASITLAQAALESGYGAYAEGNNLFGIKAKGSANSANQTTREYINGEWRQIVDRFRVYGSWAESIRDHSEFLLKNPTYTRAGVFTRSRALDYKGTARALQSAGYATDPGYANKLISIIEKYKLQEWDLQAAEEGGWIPMRLQHEWQWKQLGDALQGLLDQGVITDPSWPKKAYGKQLTLTELTWLNAVILARQSGVKV
>NC_017672.3|WP_016362364.1|1502388_1503903_+|extracellular-solute-binding-protein
MKTQRFKQISAFCALTLAASVFAGCANKTDGGAAAGNAAADTGPVKITMMANLQTPEVPSDKLEKLIEEKTNSQLEISWIPDGSYDEKFQASFATGTLPQVVYLKNQASFILMRDAMKDGQFWEIGPLLKDYPNLKSLNQETLKNTAVAGKIYTLYQERQPSRTGIIYRKDWADKLGLAAPQSADDIYNMLKKFKETDAAGKGNTIPLSDRNDLVYGAFKTVSMYFGTPNNWGVVDGKLVPEFETKGYLDTMKFFQKLHKEGLINQDFPVTSKTDQQNLMYSGKSGMYIGTMGDVKTMQEKTVKNVPDAMYDVTNEIKGVDGKNVSWGLSGYGTVVVFPKSAIKTENELKRILGVMDKFYSPEVADLLKYGIENEHYSLKDGKVQPVQDPKLIEKEVRPYLNLALYETTNVKPALFSMPSHEKANTLSNAAEKFMVQDPTAALDSPTYNSTGSRLQDIIKDATYQFILGKIDEAGFKAAVDKWKKDGGQKIIDEYNAQYNNAGK
>NC_017672.3|WP_014649737.1|1504354_1506001_-|hypothetical-protein
MTFLSGLLHNRLQRVICVILLTAGLTWLSLWWRILDHTVSAYFQAGGFWLGLLLFLSGMVPGRDGSRKAGRLEFMAGGLLMLLWLFLAFVYGITTADDKFQAAHAEVRDAKMEQIDIKHIPSVPKTFAKYKGDKMLGQVPNFSYYQMGDYSIQKIDNELVWVAPVEYNGFFKSLSANTVTAYVKISAEDENAPAELMSGYAMKYVPSGYFSGNIYRHIRADYPSAVLFEASFEPKDDGSPVYVVPYGHYEKYRNVPYVDGVFLVDPESGTIEQYGTDQVPAFVDQVIPASIADTYNTYFGKYKHGYLNTLFGKRDLHMPTTWEEGDEVVAVFDQEGNMSWFTDHTTLDETSKSLVGYSLINARSGKFTYYGGQTVSSSGLANGSAAINSVNKTFLKDQWTGASPTLYNIYGEETWFVPVTDGNGLLRELALVNAKNPQILAHHKNKASAFASYKNLLVSFGSGQMDPTGSAQQKEIQGRIVRVSFVSEGADLRVKWMMDNSDKVFVVLESQYPYAGFLQAGDQVRVQYVDTEELVVTASKVTNLTVNK
>NC_017672.3|WP_014649738.1|1506223_1506541_+|hypothetical-protein
MLNLGELEELHADIQSVHEIVQSLKARVDGQEIGIRICRNANGHYFYELSHTYRGADAADPEVGVVNSFDSAEEAAKGALRSAVLYYRSMDEGGRWHRNDSFLIQ
>NC_017672.3|WP_014649739.1|1506715_1507702_-|sugar-ABC-transporter-substrate-binding-protein
MPLSRKLGLILALAAGMTLVLVSCRGLWPGTGESPLPGTGEPKVQASEPKTFAILYPMSHPYFEWITESTEAAAKEMGVKLLVKAPDEAHLEQQIRMLEMMIKQKVDGIAIDPVDAETLTPYIDKAVEAGIPVVCFDSDAPVSRRLAFIGSDNTQAGRQMGAVIDKMLKGRGMIFIGTGMESMLSQQQRLRGLLDYLHEHTGIQVLEIRANEGSEDLAVAQLEEMIEAHPHFDAFIGLDSVSGPASILVWKAMGLHRTAATFDLTPKIIEGIKNGQVSAALSRQEHTWGRLIVKRLLQASQGLAIPEFEETGTVVVTPENVRDTDGWR
>NC_017672.3|WP_014649740.1|1507685_1509323_-|response-regulator
MKKVFLVDDEIVIREGIRDRIAWNEEGFEYCGDAPDGELALPLIEETKPDIVITDIKMPFMDGLELSRIIRERFPSIKIIILSGHDEFEYAREALRTGVTEYCLKPVSSADLIKLLQDVSALIDREEREREEMERLKRRVSDGVRHSREKLLSDLCSGLVTTSEAMQTAAKLQLNLVSKCYAVVLSEQECPADAPEAEEVCRRLEELMHGRFGETASYLSFKRSKKETVWILQGDSAAQLQDLGEKLLKPLAEEAHTALSSRVRFGLGSIQDRLQGLYPSFQEAEESLKRQLLPGRPQGPGGDWQGGGEAGGPLRYLDRSPLIRFLKLGSPAAVPSFVREYAACLSEWDGSRSFYYYYLLHDMTATVSQLAKESYPEHERIEDMLQALQSQVGLIQRADEAYRYLEGMIGAFLQVRDGNADKYSGLIRRVKDYMHANYGQSELSLQHIAEHVRMSPSYISSVFSSETGQTITEYLTGLRIGKAMELLRSTHAKSYEIAYQVGYQDSHYFSNLFKKSTGMTTREFRRNQAQSGHPDEGEERHAALS
>NC_017672.3|WP_014649741.1|1509331_1511131_-|sensor-histidine-kinase
MRLVQRITSSLRAKLLTIFVLLTMIPLIGEGLISYMKSYQTVSEHSTAANALIAEGLRRDIDILFQDTTSFLQIRKSPPVLRFLTAQSETYEDAKEILHTFELYRETYKLGGQIVNISMVNTYGKGISEKKGVFQMDADPLKNPHFLTLLNNPEQTLIIPPQAARPEDRMDGSDYEGRRVISIAKAVTQRVTHEIIGFILIDMDDRTVENFCNTTLIGETGFFYVVDEQGNPIFLPSRVEGLDPAALTFAADTDKGSRTDRSAGEPLFYVHTRSEMTGWSIVGRAPLKEIMRDADEIKSLTLYSVLFNILFTVSLYFFLTNRLIRPVQYLKNKMRQAASGNLDAKARNTGTDEIADLGHSFNIMLGQIKQLLERSLKEQEQIKKAELRTLQAQINPHFLYNTLESIMWMAETRKHDEVIALVKALSQFFRITLSKGRDQIHIKSELDHIENYLVIQRMRYRDILDYEVDLPEELNPYPIVKMSLQPLVENALYHGIKNKRGRGLIRITGGFTPDGDIRIEVRDNGAGIPGARLAQLQEQLAHGQSAAALEANASSSGGFGLLNVHQRIRLHYGSPYGVSIESEYGVGSCISVRIPAAWR
>NC_017672.3|WP_014368868.1|1511411_1512461_+|ABC-transporter-substrate-binding-protein
MKQFAKTGAVLMMSAVLMLTAACGGGGSKPAAGDAKSGAAAETNTSTAQKDGDKKITMGFAQVGAESGWRTANTKSIQEAAKEAGVELKFSDAQQKQENQIKAIRSYIAQKVDVIAFSPVVESGWETVLKEAKDAGIPVILTDRAVDVKDTSLYVSFIGSDFVEEGRKAGKWLVDKAKDTKEPMNIVELQGTTGSAPAIDRKQGFEEVIKENANLKIVKSQTGDFTRTKGKEVMEAFLKSSKSENKPIHVVYAHNDDMALGAIQAIEEFGLKPGKDILIISVDGIKDAFVAMKDGKINVVVECNPLLGPQLMQAAKDVVAGKSLPKRIVTKEGVFPQETAEKELPNRKY

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_2

1547298-1547371

Orphan

Consensus_repeat	Method
ATAAGGCATCTGAGTTCCGCTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_2

>merge|NC_017672|2|1547298-1547371|CRISPRCasFinder
ATAAGGCATCTGAGTTCCGCTATTTGTTGGGAAATGACGGGAAATACCGGGATAAGGCATCTGAGTTCCGTTAT

>NC_017672|2|2|1547298-1547371|CRISPRCasFinder
ATAAGGCATCTGAGTTCCGCTAT	TTGTTGGGAAATGACGGGAAATACCGGG
ATAAGGCATCTGAGTTCCGTTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_013917177.1\|1549741_1550989_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_017672.3\|WP_016362369.1\|1551523_1552369_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014649758.1\|1543870_1544818_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_051220055.1\|1554220_1562101_+\|carbohydrate-binding-protein	unknown	unknown	gnl\|CDD\|224389
NC_017672.3\|WP_014649754.1\|1536002_1537022_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|236863
NC_017672.3\|WP_014649760.1\|1545898_1546888_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_017672.3\|WP_014649766.1\|1552518_1553022_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_017672.3\|WP_014368904.1\|1562291_1562690_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_017672.3\|WP_014368889.1\|1537782_1538691_+\|ribokinase	unknown	unknown	gnl\|CDD\|238579
NC_017672.3\|WP_014649762.1\|1549346_1549502_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013917172.1\|1545501_1545693_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014649761.1\|1548025_1549012_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NC_017672.3\|WP_014649756.1\|1538797_1539220_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378100
NC_017672.3\|WP_014368891.1\|1539558_1540107_+\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|292911
NC_017672.3\|WP_014649759.1\|1545180_1545369_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014649757.1\|1540360_1543546_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|223446
NC_017672.3\|WP_013917163.1\|1535344_1536010_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NC_017672.3\|WP_013917184.1\|1562904_1564320_-\|SpoVR-family-protein	unknown	unknown	gnl\|CDD\|377285
NC_017672.3\|WP_014649767.1\|1553165_1553975_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013917185.1\|1564316_1565477_-\|sporulation-protein-YhbH	unknown	unknown	gnl\|CDD\|274336

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_013917177.1\|1549741_1550989_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.77971e-24
NC_017672.3\|WP_013917184.1\|1562904_1564320_-\|SpoVR-family-protein	gnl\|CDD\|377285	pfam04293, SpoVR, SpoVR like protein. Bacillus subtilis stage V sporulation protein R is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR.	0
NC_017672.3\|WP_014649757.1\|1540360_1543546_+\|cytochrome-P450	gnl\|CDD\|223446	COG0369, CysJ, Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism].	1.85916e-171
NC_017672.3\|WP_014649761.1\|1548025_1549012_-\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	0
NC_017672.3\|WP_014649760.1\|1545898_1546888_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.8279e-60
NC_017672.3\|WP_014649766.1\|1552518_1553022_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.34922e-39
NC_017672.3\|WP_014368891.1\|1539558_1540107_+\|TetR-family-transcriptional-regulator	gnl\|CDD\|292911	pfam16295, TetR_C_10, Tetracycline repressor, C-terminal all-alpha domain.	4.10919e-76
NC_017672.3\|WP_014368904.1\|1562291_1562690_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	6.6195e-08
NC_017672.3\|WP_014649754.1\|1536002_1537022_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	0
NC_017672.3\|WP_014649756.1\|1538797_1539220_-\|hypothetical-protein	gnl\|CDD\|378100	pfam08937, DUF1863, MTH538 TIR-like domain (DUF1863). This domain adopts the flavodoxin fold, that is, five parallel beta-strands and four helical segments. The structure is a three-layer sandwich with alpha-1 and alpha-4 on one side of the beta-sheet, and alpha-2 and alpha-3 on the other side. Probable role in signal transduction as a phosphorylation-independent conformational switch protein. This domain is similar to the TIR domain.	2.05452e-06
NC_017672.3\|WP_014368889.1\|1537782_1538691_+\|ribokinase	gnl\|CDD\|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	2.08419e-126
NC_017672.3\|WP_013917163.1\|1535344_1536010_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	3.45996e-104
NC_017672.3\|WP_051220055.1\|1554220_1562101_+\|carbohydrate-binding-protein	gnl\|CDD\|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	3.65607e-85
NC_017672.3\|WP_013917185.1\|1564316_1565477_-\|sporulation-protein-YhbH	gnl\|CDD\|274336	TIGR02877, Stress_response_UPF0229_protein_YhbH, sporulation protein YhbH. This protein family, typified by YhbH in Bacillus subtilis, is found in nearly every endospore-forming bacterium and in no other genome (but note that the trusted cutoff score is set high to exclude a single high-scoring sequence from Nitrosococcus oceani ATCC 19707, which is classified in the Gammaproteobacteria). The gene in Bacillus subtilis was shown to be in the regulon of the sporulation sigma factor, sigma-E, and its mutation was shown to create a sporulation defect. [Cellular processes, Sporulation and germination].	0

>NC_017672.3|WP_014649760.1|1545898_1546888_+|Gfo/Idh/MocA-family-oxidoreductase
MIRFGIIGTNWITETLIEAALRTGKVTFTAVYSRTREKGREFADKFGIPHVYTDLEAFGESTEFDAVYIASPNSLHAKYAVQLMNYGKHVLCEKPLASHAREVREMIDAAKSNNVLLMEAVKSTLMPSFRAVQEHLHKIGPVRRYTASYGQYSSRYDAYKQGTVLNAFKPEFSNGSLMDLGVYCIYPMVVLFGRPQRVQAEAFMLESGVDGEGSLLLKYEGMDAVIMHSKIANSYLPAEIQGELGTIVIDRINDPGRVEIRYKDGRVEDLTQPTEHPSMYYEVLEFAALLEAGATESAVNSHGSSLAAMQVMEEARKQIGLVFPADSES
>NC_017672.3|WP_013917172.1|1545501_1545693_-|hypothetical-protein
MRTEDQIRRKANELLLQKKSVEERLTAAEEDRKPGLQSELDRLDDMILLLEWVLNKPVGSYHG
>NC_017672.3|WP_014649759.1|1545180_1545369_-|hypothetical-protein
MPVAVVAAALLNTIVGQMAWTYGWWRFKETLFAWDRVIPRFSVYGFFPAGTIWIFVFAYRKF
>NC_017672.3|WP_014649758.1|1543870_1544818_-|hypothetical-protein
MKKKPSCAAPLLLLLLAACSPLSTPADVGNIESAANGAGGSTASVPTAVGTETAASGPAYVKPEDLKAVPLVFGRIESPALEKTAAPETASPAKVYECSAAPGLPSCSVHLYEERADNGYIGVRVFLRVPDGWYAAGSSIAGDADSLAVRFLPQGSGPAEDGPMELAIGGAPDDSYAGPVRTLFYDAEKRVWRMQDFQGHDVQRLDLNQDGQAEWISPSVDWVPPSVGIYRWNSTARAYEYTVVENVAAAAFGLTLEQVPLHAYLFKESGEWIIETGPSDRYGFFRQEGDQLVPALLTDEHSRLMDLRRTQGHRH
>NC_017672.3|WP_014649757.1|1540360_1543546_+|cytochrome-P450
MTQTSQIPQPKTFGPLGNLPNLNTKEPVQSIVKIADEFGPIFQLDLPRGKSVYISSHELVADACDESRFDKYVWAPLQKVRAFAGDGLFTAETDEPNWQKAHAILLPSFSQRAMQGYHAMMVDLAVQLVQKWARLNPDESVEVGEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMSQLQRLGLQDKLMVISKRQYKHDIQTMFGLVDKIIAERKEHGSKEGEDLLAHMLNGRDPHTGEALDDENIRYQIITFLIAGHETTSGLLTFALYFLLKNPEKLAKAYEEVDRVLTSPLPTYSQVRELKYIRMILNESLRLWPTAPAFALTAKEDTMLGGRYPMQKGDSVSVLIPKLHRDPSVWGDDVESFIPERFEDPSSIPPHAYKPFGNGQRACIGQQFALHEAVLVLGMVLRHFEIIDHTNYQLKIKETLTLKPEGFTMRVRSRIEPLAVVMPGREAAPLEEKREQAAEAAPVPKHNTPLLVLYGSNLGTAEGIARELADAARYQGFSSETAPLDEHVGSLPKEGAVFIVTASYNGSPPDNARAFVQWLEQAEPGSLDGVRYAVFGCGDHNWASTYQQVPRKIDALLADKGAKRLAGLGEGDVSDDFEQQLESWRGGLWPQVMEAFGLSLNENAGQERSSLTVQFVSGLIGTPLAESYDALQTTVAENRELQGEGSDRSTRHIEVVLPEEVSYREGDHLGVLPLNPKDLVGRVLQRFGLQGGDHLVLSATGRSAAHLPLGRPVRLSDLLGSSVELQEPATRAQLRELAAYTVCPPHKRELEALLQEDAYKTEVLRKRVTMLELLEKYPACELPFERFLELLPPLKARYYSISSSPRVLGDRVSITVSVVRGPAWSGRGEYRGIASNYLAERKPGDPVVVFVRSPESGFELPEDPSTPVIMVGPGTGVAPFRGFLQARRVLKAQGAELGEAHLYFGCRNPQHDYLYREELEQAERDGLVVLHTACSRVDGQEKTYVQDLMKGDASLLIGLLDRGGKLYICGDGSRMAPDVEATLRRAYSEIHGVSGQEAADWLDGLARENRYAKDVWAGTAG
>NC_017672.3|WP_014368891.1|1539558_1540107_+|TetR-family-transcriptional-regulator
MSAALELFAEQGFETTTVPMIADKAVVGAGTIYRYFTNKEALGNALFQDCVRQFSEAIQRGYPAEGNAREQFRHIFCRMVEFAKEQERAFYLLETHRHARYLSEESHELFREMMDFLRAYFRAGREQGTIRSMPSDALIAIVYGAFAALYKAIRAGKIQETPDLIDSVEQACWDAVRVHPHG
>NC_017672.3|WP_014649756.1|1538797_1539220_-|hypothetical-protein
MTVYDTNRVYTLYLSHTWNDRGTGGELLRMLQSVDSFRFRPASLDRQTSETADDRILYEAIRGKIRYADVILILCGVYAEYNRWVNKELILAKNELNKPVIGVQPFPAEKPPFIVKQHADRIVQLHPLDIIKAVMELGQG
>NC_017672.3|WP_014368889.1|1537782_1538691_+|ribokinase
MKRPRIAVVGSLNMDLVVSMPRMPQVGETVHGTDIHYIPGGKGANQAVGCARLGAEVSMIGAVGSDHFGREMLERLQEEGIDLGGVHTAEGPTGTAAIFHTAEDNCIAVVPGANAYCTPELVERHRERIESADVLLVQLEVPLDTVHRALEIARQAGVRTVLNPAPAKVLPAPLLSLADILTPNETEFALLSGEQDTSEEVLRRVMIAWQQDYGHTVILTRGRLGSSWLDEGERLRTEPALPVETVDTTGAGDAFNAALCFGLASGWDLQQAADFACRAASVSVTRFGAQAGMPRLEEVPER
>NC_017672.3|WP_014649754.1|1536002_1537022_-|methionine-ABC-transporter-ATP-binding-protein
MIQLQGVSKQYTSGRGTVTALQKIDLTVNKGEIFGIIGHSGAGKSTLIRTINLLEKPTGGTVIIDGVEMTKLSSRRLQEERRSIGMIFQHFHLLSSSTVADNIAFPLRLSKRPEAEIKQRVQELVGLVGLSGHEHKYPSQLSGGQKQRVGIARALATNPKVLLCDEATSALDPQTTNSILSLLLDINRKLQITIVLITHEMHVIRTICDRVAVIDGGHIVEMGPVTDVFLKPQHPTTRDFVAQLAEDPETTLAETGAEASGRIRIRVTFLGEQTYEPVLFETMRETNVPFVILQGTVSRLKDTPYGQLLLELRVNTAEAEAAITALRRRGLDVEVIQHG
>NC_017672.3|WP_013917163.1|1535344_1536010_-|ABC-transporter-permease
MAEFLKDIVWEDISLATYDTLTMLGLSTLFTVVIGLPLGILLFLTSRGQLLQQNALYALLSFVVNVLRSVPFIILMILVIPLTRVIVGTSIGVPGSIPPLVIASAPFFARLVETALREVDRGVIEAAQSMGATSGQIVTRVLLPEARPGLIAAITITAVTLVSYTAMSGVVGGGGLGDLAIRYGYQRFNTPVMVVTVVILLVLVQILQSLGDRLVRRFQRK
>NC_017672.3|WP_014649761.1|1548025_1549012_-|aldo/keto-reductase
MKTRTLGRSNLEVSSLGLGCMGMSDFYSGRDEEESIRTIHRSLELGVTFLDTADMYGVGRNEELVGRAVKDRRDAVVLATKFGNVRSEDGQFLGVNGRPEYVRSACEASLRRLGVDHIDLYYQHRVDPNTPIEETVGAMAELVREGKVRYIGLSEAAPATIRRAHAVHPVTALQTEYSLWSRDVEDEILPVCRELGIGFVPYSPLGRGFLTGQIRRFEDLAEDDYRRFSPRFQGENFQKNLDLVERIREIAAARNVQPSQLALAWLLAQGDDIVPIPGTKRTVYLEENVGALDIELTPEELGRIDEAAPKGAAAGSRYPEASMSSLNL
>NC_017672.3|WP_014649762.1|1549346_1549502_-|hypothetical-protein
MHYFELELHMTERQQIIRQKSRGLLRRSIKQVWRTTHEYTMTLIACILLAG
>NC_017672.3|WP_013917177.1|1549741_1550989_+|MFS-transporter
MGDGEAMDEDRIINFSGLRMSRDTWHNFRWDVAAASVFSLFNVVFNQFYIPIALRHGASDFEVGLLAAAPAVGLLFSPAWAGLMEGRSPKPFFLLPNLIGRLLLIIPALYSTPVMFVLTAFLFHLLMGIQAPAYAALMTRLYPADQRGRLMGNVRVIMGLLMLPLAWVTGLWIDASGSSGPLLVAAVTGALSLIAFQQVREVPRFFAGGKGEALRLSLFGQLRLLRGNRPVLIFLAATSLAGFGNMLASPLYAIYQVNELGLSNAQIGYLRMAYFACMLLAYLIAGWAIDRFSPQAVMACGLTAMTTVPFLYGLVGTFPAVLAASGIQGISDAVWDIGCMAFVFHFARGREAVVFGLHLMLFGIRGTAGPLIGTSLNGAMPFGGMMLFVGALGLAGLLLFLGSRIRSEDGVTAEE
>NC_017672.3|WP_016362369.1|1551523_1552369_+|hypothetical-protein
MEWRKHHENNARISRWVGGGLLAAAAVYGMLDWKYGWSTRPAMAITVSGMVLTAVIILGTASAFMRKAAFFPEERRERDRELQDGSGQDPFLHRDREMMLMRQGGKGTRALIRYFSVDGDLLLEFRETSRGWVFAADWILDRLRPFLPKSFVLTDRIGGPRLYLTQRGGINSPIEIRLPDGTLIGSCRQDWWKARMELRDGAGLPAGEVGSDDLLGTSFRVRDASGRELVRFYNGGLPSRNGDAFSSDADLVKVSAELAGEPEAYVRFIAVPALIKIVFSR
>NC_017672.3|WP_014649766.1|1552518_1553022_+|signal-peptidase-I
MLHFILALLLTTGIPGTTPAVKSYQAMGPSMEPAIHQGDRLGVDTEYYQTNAFRRGDLVLFPVGEDKIYFKRIIALGGERVRVDGDDVYINGTKLDEPYLADGLKRAAELGSPYNVRDFVETVVPKGAVFVMGDNRSNSMDSRDAAVGFVPYASILGRVVTVQHTDQ
>NC_017672.3|WP_014649767.1|1553165_1553975_-|hypothetical-protein
MNMNGTYGGARSIDEVLLQLDRVVEEARSSSSRLGYFAALYRMVTRKVKEGIAQGFFEDGPRMERLDVIFANRYLEALNAHLHGGRPTDCWALSFRSAGNSRLLILQHLLLGMNAHINYDLGIAAAQTSPGAEIGSLYADFNKINSILAGLVGRVVDEIQELSPWIRLLDRIDTKAEFAVINFSMMKARDCAWQVAERLALGDDAADTSYLLQLDNDVTYLGGKVADPGFWLNLGLGVIRSRESSDIPRVIDVLSGTGTDAAPPLDQAV
>NC_017672.3|WP_051220055.1|1554220_1562101_+|carbohydrate-binding-protein
MEWDEIDSIKNRTGGTTLKLKRQLSAVTAAVVLGSTLAAPFTASVSAAESPAELAPYWNPKLPVEERVQDLLGRMTLDEKVGQMVQAERAHATPEDVKMYYLGSMLSGGGSFPGGRQANSTRGKWAELYDSYQNGALSTRLGIPLLYGVDAVHGHSNVIGATLIPHNIGLGAARNSELMKKLGALTAKEMRATGVNYAFGPTIADVQNPRWGRTYEGLGDDSVLAGQLGAAYIQGLQGAGGGELSRPDKVVATAKHFMGEGYTDNGTNQGDVSTKTYTEEEIRELLERELAMYKQAVDAGVKSVMASYNSIQGLKMHANKPLLTDKLKGELGFRGFVITDWNGVDQITKDWEGRPVSGLKEQVRAAVNAGVDMFMEAEKWRDIVRYLKENVNEGGIPGERVDDAVKRILRVKFESGVFELPKTNGDLAPSFGSAEHRELARQAVRESLVLLKNDKVNGQPLLSKLPSMKKIFVAGKNADDIGNQAGGWSITWQGQSGPTTPGTTILQGIREAAGDKRTVTYNKHGRGAAGYDVAIAVLGEKPYAETNGDTASLELDVEDLATLENIRTADPDIPILVVLVSGRPMTVTEPMKDWAGLIAAWLPGTEGAGVADVLFGGHDFTGRMPMRWPFYVEAYPIKTADSPYILFPTGYGLTKGEMTPELPPVPEKPGQPAYSPKPVPGRVEAEDFTAQNGLQLENASEGTQNLGFADAGDWSDYTVNVAQAGTYEVDFRYAGEMGSPTSIRIKDEAGRTAGTFSGGATGGWQSWRTGTAANVVLKQEGVQKLRLEFGGSINLNWLEFRRTGDVPADNSGGGDSGSGAVVKSGAVESWITNERDPGDIRWYYAPRYREGDKKLEAQPKLDLVMPGGGSGTEIKLDPEKTYQSMFGIGSSMEESTVHNLWKMSPAKRTEVLKKLVDPQEGAGMSLIRLTIGSADFTAQTFYSYDDMPAGGTDPELKHFSIQKDREFHIIDTVKEIQRINPDVKFFASPWSPPGWMKTTDSLMKGQVKDEYLPVLAKYYLKYLQAYRAEGIEIEAMTMQNEPLLEIEYPSAKMPREQQAKLAKLLRAELDANGFSHVKLWTFDHNPGDTMAYPAQLLRDPANREAVDGTAFHDYGGDLGEMTKLHDMYPEEHVYLSERAVWGTKGADRMAQYFRNWARSYNSWVVMLDSDIRTHQWVGTPDPTPLVQDSADRDNYWLAPEYYLLGQYTKFVEPGYVRIDSNYGSADTVTNVAFRSPDGKKIVTVVINQTNEDQPVKLLSDGTQIKATVPAKSVVTYRWDRVVAKQAVPGAIRAADFDHAAGSYKADGETGTVGGLNEGAGEPASFDYLVNAAESGTYYADLGYTGVPQDASLRLLKDDAEIAAVPLSQEVSGGGPAGYARVSVALEAGIHKLTLTAQGRGYTLTDLVLSKADPGLHSVPGLIEAEGGTLLPGTLADRNADGVIVRFTPDAEGAEYRFHAEQGGEYRMTYRYAAEGVGAAAELSVEGTVIGTTYLPVTGGRDQWAYAADTVTLPAGDHVLKLAVKDSPVRQDWLAVGPTMIAAAGAPVTEGQENGTPITVELLNDTFRETLHAERWSLEGAEGVSVGSVTRLDDRRAQVVLSGTRTADYDKDIRGAVTAAVYETVSGSVYASGVLRSRLAFTAVEDAETLVMADGPLPYGVDGRVLELALEGGTFRTGALDGITLAGSAVTQGGVSLKSVRAVDASHLELTLGWNGTAYYGDLQLEVRVPKEAYADGEAALTAAAVLSGTVNRQEAVPVPGLVPADAFYKVQGAAADAGPDGTRKLTGFDAGDYAEYKINAAQAGTYLAALRITFESGAAKGIVLKNGAGETLAEYTVPQLYNKNWVTVGSRITLPAGEQILRVYAQAGGFELGSLTLEPVTAQAMDEQGVLRVEAESYTGATVGVIQDNAASGTAPAFRNVGYMSAGNTLDYLVDVLEDGYYRVTYRYATAQGGVSAAFTVGGQVLGTAQLPATGGWGTYKEASHVVSLRKGVQTITLLDQGDGFNLDWFELQPSDAPEQAVTDQAAVPAASLRAGTYYGSREVALSTLTEGAAVFYTLDGTVPTAAGTPYTGPIEVTGLTVIRAIAVKAGMKDSYVAPYTYVVEAGEQPPEQAAAPVASPGPGSYTVPQQVVLTTATEGAVLYYTLDGSAPSAAAGTEYKHAITVPVGTTTIKAIAVKEGMADSAAAEFTYVITAPGNGGGNNGGGNNGEGNNGGGNTGGSEGDSSDGGTPGGGAVSTPAPADGGPPVLTTPQPALDAETGIASVTVPAAELEKALAGRSSVTVEVPQTAGAKAYGIVLPASVLTEGSGKHTLEVVTEAARLILPSGMLASAGGAQQIELRIGIADPSGLSAPLRGQLEGRPVIELSLFADGRPLEWSNPDAKAAVSIPYKPGADELAHPDWITVWHVDAAGVVTAVPSARYDGESGRVTFTTTHFSRFAVAYVTKAFGDLTAHAWAREAVETMAAKGVIQGTAEGVFTPSAPVTRADFLLLLVKALDLSAGFTGNFDDVDPSAYYYQAVGIAKKLGITEGREGKRFDPASPISRQEMMTLAERALKLAGRELPAGDESVLGGFADRADLSAYAAESTAALVKSGLITGDGSRLNPLGTATRAETAVLIHRLYQR
>NC_017672.3|WP_014368904.1|1562291_1562690_+|helix-turn-helix-transcriptional-regulator
MSTWYGQQLRELRELKGMEVTEFAKELGVSPGYLRNLESGRTQTIQLEILSRLEKELYWSVDEELAKEEEAEEEAAREPEDSPRLDRALRELRELTAADPPAGEYLLGMLEQGLRLVRDRRQPDMPPAAASE
>NC_017672.3|WP_013917184.1|1562904_1564320_-|SpoVR-family-protein
MKLDDIKKLEYAIAEITEVATGFGLDFYPMRYEICPAEIIYTFGAYGMPTRFSHWSFGKTFHKMKMQYDFGLSKIYELVINSDPCYAFLLDGNSLIQNKLIVAHVLAHCDFFKNNVRFSKTNRNMVESMSATAERIRQYEIEYGNEEVEKFIDAVLAIQEHVDPLITKPVRGMSGLRTEAAAPPTERTFGYEDLWDLDEKPKPPERKEGPAKFPPRPEKDLMLFIEEYAPYLKDWQRDIMTMLRDEMLYFWPQMETKIMNEGWASYWHQRILRELDLTEDETIEYAKLNSSVVVPSRHSLNPYYLGLKIFEDIEKRWDHPSKEDRERFGYKGGEGRQKIFEVREFDSDSSFIRNYMTKQLVDELDLYVFEKKGPEWKITDKSWENIRDQLIFARVNGGFPYIVVEDGDYERSGELYLRHMFEGTELDLKYVERTIPYIHRLWGKPVYLESVIEGKPVLFSYDGRKHNRKFL
>NC_017672.3|WP_013917185.1|1564316_1565477_-|sporulation-protein-YhbH
MTEPLFTVSREDWSLHRKGYQDQTRHQEKVREAIKQNLPDLVTDESIVMSDGKQIVKVPIRSLDEYRFRYNYNKSKHVGQGDGDSQVGDVLGVDPQPAKGSGKGEGAGDQPGDDYYDAEVQMEELQTMLFEELELPNLQQKEKNNVTTKEIIFNDVRKKGIMSNIDKKRTIMENLRRNSREGTPGIHHISPDDLRFRTWDEIVTPHSNALILAMMDTSGSMGSFEKYIARSFFFWMTRFLRTKYEHVEIVFIAHHTEAKEVTEEEFFTKGESGGTICSSAYQLAVDLIDRKYPPSRYNIYPFHFSDGDNLTSDNERCVKLIGELVKRANLFGYGEVNQYNRSSTLMSAYRNIHDPKFVHYVIREKGEVYKALRTFFPKNVEGRAAR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_3

3108799-3109154

Orphan

Consensus_repeat	Method
ACGGAAAATCCGTCTTCG	CRT

6 spacers

The CRISPR arrays of NC_017672_3

>merge|NC_017672|3|3108799-3109154|CRT
GCGGAAAATCCGTGTTCGGAGCCGGAAGCCTCGGACATTCGGCCGAACGCAGCCTCTGTAAGACGGAAAATCCGTCTTCGAGCGGCCAATCCGCCCCCAGCAAGCTGGCTAACACGGAAAATCCGTCTTTGGAGCCAGAATCCTTCGGGAATCGGCCGAACGCAGCCTCTGTAAGACGGAAAATCCGTCTTCGAGCGGCCAATCCGCCCCCAGCAAGCTGGCTAACACGGAAAATCCGTCTTTGGAGCCAGAATCCTTCGGGAATCGGCCGAACGCAGCCTCTGTAAGACGGAAAATCCGTCTTCGAGCGGCCAATCCGCCCTCGGCAGGCCGGCGAACACGGAAATCCGTGTCCG

>NC_017672|3|1|3108799-3109154|CRT
GCGGAAAATCCGTGTTCG	GAGCCGGAAGCCTCGGACATTCGGCCGAACGCAGCCTCTGTAAG
ACGGAAAATCCGTCTTCG	AGCGGCCAATCCGCCCCCAGCAAGCTGGCTAAC
ACGGAAAATCCGTCTTTG	GAGCCAGAATCCTTCGGGAATCGGCCGAACGCAGCCTCTGTAAG
ACGGAAAATCCGTCTTCG	AGCGGCCAATCCGCCCCCAGCAAGCTGGCTAAC
ACGGAAAATCCGTCTTTG	GAGCCAGAATCCTTCGGGAATCGGCCGAACGCAGCCTCTGTAAG
ACGGAAAATCCGTCTTCG	AGCGGCCAATCCGCCCTCGGCAGGCCGGCGAA
CACGGAAATCCGTGTCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014650570.1\|3098649_3099099_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182510
NC_017672.3\|WP_014650576.1\|3103110_3104331_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350126
NC_017672.3\|WP_013916109.1\|3120341_3120500_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014650573.1\|3101550_3101844_+\|fatty-acid-CoA-ligase	unknown	unknown	gnl\|CDD\|341284
NC_017672.3\|WP_014369824.1\|3117720_3119094_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NC_017672.3\|WP_014650568.1\|3095578_3096427_+\|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	unknown	unknown	gnl\|CDD\|184561
NC_017672.3\|WP_014650569.1\|3096550_3098518_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_041618650.1\|3119346_3120261_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|307170
NC_017672.3\|WP_014650575.1\|3102085_3102937_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187627
NC_017672.3\|WP_014650582.1\|3113907_3114645_+\|ribonuclease-Z	unknown	unknown	gnl\|CDD\|293830
NC_017672.3\|WP_014650574.1\|3101847_3102096_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014650583.1\|3114886_3117481_+\|glycoside-hydrolase-family-2-protein	unknown	unknown	gnl\|CDD\|225789
NC_017672.3\|WP_016362544.1\|3107800_3108652_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014369820.1\|3111284_3112046_-\|response-regulator	unknown	unknown	gnl\|CDD\|333815
NC_017672.3\|WP_014650579.1\|3109527_3110685_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_017672.3\|WP_014650577.1\|3105217_3107278_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227511
NC_017672.3\|WP_014650581.1\|3112086_3113832_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|225827
NC_017672.3\|WP_014650586.1\|3120701_3121115_-\|DUF2203-domain-containing-protein	unknown	unknown	gnl\|CDD\|378330
NC_017672.3\|WP_014650587.1\|3121487_3122330_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014650571.1\|3099286_3101077_-\|oligoendopeptidase-F	unknown	unknown	gnl\|CDD\|341071

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014650570.1\|3098649_3099099_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182510	PRK10514, PRK10514, putative acetyltransferase; Provisional.	1.66831e-40
NC_017672.3\|WP_014650576.1\|3103110_3104331_+\|hypothetical-protein	gnl\|CDD\|350126	cd18614, GH130, Glycosyl hydrolase family 130; uncharacterized. This subfamily contains glycosyl hydrolase family 130 (GH130) proteins, as classified by the carbohydrate-active enzymes database (CAZY), most of which are as yet uncharacterized. GH130 enzymes are phosphorylases and hydrolases for beta-mannosides, and include beta-1,4-mannosylglucose phosphorylase (EC 2.4.1.281), beta-1,4-mannooligosaccharide phosphorylase (EC 2.4.1.319), beta-1,4-mannosyl-N-acetyl-glucosamine phosphorylase (EC 2.4.1.320), beta-1,2-mannobiose phosphorylase (EC 2.4.1.-), beta-1,2-oligomannan phosphorylase (EC 2.4.1.-) and beta-1,2-mannosidase (EC 3.2.1.-). They possess 5-bladed beta-propeller domains similar to families 32, 43, 62, 68, 117 (GH32, GH43, GH62, GH68, GH117). GH130 enzymes are involved in the bacterial utilization of mannans or N-linked glycans. Beta-1,4-mannosylglucose phosphorylase is involved in degradation of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine linkages in the core of N-glycans; it produces alpha-mannose 1-phosphate and glucose from 4-O-beta-D-mannosyl-D-glucose and inorganic phosphate, using a critical catalytic Asp as a proton donor.	1.04169e-28
NC_017672.3\|WP_014650573.1\|3101550_3101844_+\|fatty-acid-CoA-ligase	gnl\|CDD\|341284	cd12119, ttLC_FACS_AlkK_like, Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles. This family includes fatty acyl-CoA synthetases that can activate medium-chain to long-chain fatty acids. They catalyze the ATP-dependent acylation of fatty acids in a two-step reaction. The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. The fatty acyl-CoA synthetases are responsible for fatty acid degradation as well as physiological regulation of cellular functions via the production of fatty acyl-CoA esters. The fatty acyl-CoA synthetase from Thermus thermophiles in this family catalyzes the long-chain fatty acid, myristoyl acid, while another member in this family, the AlkK protein identified from Pseudomonas oleovorans, targets medium chain fatty acids. This family also includes uncharacterized FACS proteins.	6.33534e-31
NC_017672.3\|WP_014369824.1\|3117720_3119094_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.09226e-116
NC_017672.3\|WP_014650568.1\|3095578_3096427_+\|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase	gnl\|CDD\|184561	PRK14192, PRK14192, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	3.55448e-133
NC_017672.3\|WP_041618650.1\|3119346_3120261_+\|DMT-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	3.15287e-13
NC_017672.3\|WP_014650575.1\|3102085_3102937_+\|SDR-family-oxidoreductase	gnl\|CDD\|187627	cd05369, TER_DECR_SDR_a, Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR. TTER is a peroxisomal protein with a proposed role in fatty acid elongation. Fatty acid synthesis is known to occur in the both endoplasmic reticulum and mitochondria; peroxisomal TER has been proposed as an additional fatty acid elongation system, it reduces the double bond at C-2 as the last step of elongation. This system resembles the mitochondrial system in that acetyl-CoA is used as a carbon donor. TER may also function in phytol metabolism, reducting phytenoyl-CoA to phytanoyl-CoA in peroxisomes. DECR processes double bonds in fatty acids to increase their utility in fatty acid metabolism; it reduces 2,4-dienoyl-CoA to an enoyl-CoA. DECR is active in mitochondria and peroxisomes. This subgroup has the Gly-rich NAD-binding motif of the classical SDR family, but does not display strong identity to the canonical active site tetrad, and lacks the characteristic Tyr at the usual position. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.36289e-121
NC_017672.3\|WP_014650582.1\|3113907_3114645_+\|ribonuclease-Z	gnl\|CDD\|293830	cd16272, RNaseZ_MBL-fold, Ribonuclease Z; MBL-fold metallo-hydrolase domain. The tRNA maturase RNase Z (also known as tRNase Z or 3' tRNase) catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors. Two forms of RNase Z exist in eukaryotes, one long (ELAC2) and one short form (ELAC1), the former may have resulted from a duplication of the shorter enzyme. Only the short form exists in bacteria. It includes the C-terminus of human ELAC2 and Escherichia coli zinc phosphodiesterase (ZiPD, also known as ecoZ, tRNase Z, or RNase BN) is a 3' tRNA-processing endonuclease, encoded by the elaC gene. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	3.38687e-18
NC_017672.3\|WP_014650583.1\|3114886_3117481_+\|glycoside-hydrolase-family-2-protein	gnl\|CDD\|225789	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].	1.8666e-110
NC_017672.3\|WP_016362544.1\|3107800_3108652_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.12664e-26
NC_017672.3\|WP_014369820.1\|3111284_3112046_-\|response-regulator	gnl\|CDD\|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	1.84006e-21
NC_017672.3\|WP_014650579.1\|3109527_3110685_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.15098e-74
NC_017672.3\|WP_014650577.1\|3105217_3107278_+\|hypothetical-protein	gnl\|CDD\|227511	COG5184, ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton].	2.44051e-49
NC_017672.3\|WP_014650581.1\|3112086_3113832_-\|GHKL-domain-containing-protein	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	1.26034e-23
NC_017672.3\|WP_014650586.1\|3120701_3121115_-\|DUF2203-domain-containing-protein	gnl\|CDD\|378330	pfam09969, DUF2203, Uncharacterized conserved protein (DUF2203). This domain, found in various hypothetical bacterial proteins, has no known function.	1.61835e-44
NC_017672.3\|WP_014650587.1\|3121487_3122330_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.20892e-31
NC_017672.3\|WP_014650571.1\|3099286_3101077_-\|oligoendopeptidase-F	gnl\|CDD\|341071	cd09608, M3B_PepF, Peptidase family M3B, oligopeptidase F (PepF). Peptidase family M3B oligopeptidase F (PepF; Pz-peptidase B; EC 3.4.24.-) is mostly bacterial and includes oligoendopeptidase F from Lactococcus lactis. This enzyme hydrolyzes peptides containing between 7 and 17 amino acids with fairly broad specificity. The PepF gene is duplicated in L. lactis on the plasmid that bears it, while a shortened second copy is found in Bacillus subtilis. Most bacterial PepFs are cytoplasmic endopeptidases; however, the Bacillus amyloliquefaciens PepF oligopeptidase is a secreted protein and may facilitate the process of sporulation. Specifically, the yjbG gene encoding the homolog of the PepF1 and PepF2 oligoendopeptidases of Lactococcus lactis has been identified in Bacillus subtilis as an inhibitor of sporulation initiation when over-expressed from a multicopy plasmid. This PepF family includes Streptococcus agalactiae PepB, a group B streptococcal oligopeptidase which has been shown to degrade a variety of bioactive peptides as well as the synthetic collagen-like substrate N-(3-[2-furyl]acryloyl)-Leu-Gly- Pro-Ala in vitro.	0

>NC_017672.3|WP_016362544.1|3107800_3108652_-|AraC-family-transcriptional-regulator
MMIPPMAEPYLFDYRRTSLHDFKEVFHAHPEMEFTYVHEGEGNLILEGRTYAISPGTLLMFHPFQLHRIRMDVAPGRPFVRTLLIFDPAVLQPYWSQFPALKEFFQSLKLSQPVSPPLCLAPGDPAVSLLTQFHDTLPQLAPHETQEEYAFLLLGFLRQLRRFRQPAAGPAAPASRCSHRAEEIMQWIQRHYADPFELERLARELHISRYHAAHLFKEATGTTILSYVHATRVRHACVLLRQTLLAIPEIGIRTGYPNPSYFCRVFREAMGTTPHQYRLRVQK
>NC_017672.3|WP_014650577.1|3105217_3107278_+|hypothetical-protein
MFWVCGFLLMSLLLPFQAAAAEVGSAVAAESSKSGVTMVAAGRFHSLALKEDGTVWAWGKDSLGNGTPYSSATPVQVKDLEEVVTVAAGGNHSLALKSDGTVWAWGQNEYGVLGEDPYKTSWRLTPVQVQGLSSVVAISANFSHNLALKSDGTVWAWGMNNAGQLGNGTTSDMYTSFYTPSQVQGLDSVIAVAAGPGTSLALKSDGTLWAWGGLVGDGTTESRSTPVQAQGLSSVVSFDAGDSRFVVKSDGTVWAWGWNGYGQLGDGTTTTRYTPVPLQELSSVAAFAADEWHSLALKSDGTVWEWGCNSKGEMCYESDIRTTPVQVQDLSSAVDIAAGFEHSLAVKSDGTVWAWGNNGYGQMGDAARTYHSTPIQVLGLGEPSPNTPEAPQWPAGNILSVTEATYNSVILNWVQAVDDTGIAGYRLYQDDLFLGNVTGTTYKVTGLKASTSYLFHLTAFDKSGNVSLPSPSLSVTTDTYTPQPEKAPLALNVKSGFYEVGSEVEVYVHAKDQQDLYAFLLKIGYDPAKLRLNQILLSKEFGVEGQSAVFSKNTSKAGLAGVSGSLLGSTTGRNGDVKSAVLKFTLLAKGSSEIVLNPGSSTADSKNQIRQLTEPVKLVILTSSIDFNGDGLVGLEDLVLISRKSGEVSGQTAGFDARYDINHDGVINVPDVQYVANKVASVAIVN
>NC_017672.3|WP_014650576.1|3103110_3104331_+|hypothetical-protein
MKPQFSYSPEPVLVPQPGCDWASKMVLNPAIVQDPEEADTLHMLFRATGPWPQKQREGKYPPYPIFLGYAVSHDRGQTWDADFSRPALAPELGWEEEELKVTDAVGRQVWNYANGCIEDPRIFPVEGQLYLSAACRLFPPGPYWLVDGDPPIETRYDYVPEWTQEGEGPFYETCRTNVTVTVLYRLDLDKLKARRYEEAFAYVGPLTEGHVSDNRDVFLFPERMKIHGRLQYVMLHRPMTPAAFPDGADLGPSIYLAAAEEIGDFASPKAEHRLLAAGRFDWEENRIGASWPPLRISEDEWLVAYHGKKDAHFGYTQSFLIVLEQEDDFPVVTHRCSERMMYAQQEWEMPTDYPTPCLFTTAGIRVGDNLVMAYGAADQKVGLSWVNWAELVAYVRLFDADGVKKG
>NC_017672.3|WP_014650575.1|3102085_3102937_+|SDR-family-oxidoreductase
MFDKELLLDKVVLITGGGTGLGRAMGERFLELGAKLAITSRREEVLAQTASELRAAGGEVFHTPCDVRDAAQVQAMIDAVEGHYGHIDVLVNNAAGNFASPTESLSPRAVDAVLNIVLHGTFYTTLELGRRWIAAGRGGTMLNIVTTYASTGSAFVVPSAAAKAGVLALTRSLAVEWARYGIRQAAIAPGLFPTDGAWSRLAPTPELAEKLVQGVPLKRVGEKAELANLAAYLISDYAGYINGEVVTIDGGEWLQGAGQFNDLLEVTPEEWSELAGVTRKGKS
>NC_017672.3|WP_014650574.1|3101847_3102096_+|hypothetical-protein
MNHTLIGLNLRMNAVQGRLKQVEPAVLTADEHGQSSEAEAAAAEHPAKWLARGLFGGYRRLRKKGWAVPGSRQAGRGRRHVR
>NC_017672.3|WP_014650573.1|3101550_3101844_+|fatty-acid-CoA-ligase
MTVSRLAHPAVFEACVIRVPHVKWDERPLAFVSWKEGAEGTAGKEELPAFLGERFVKWWIPDDVVVLKEIPRTSVGKFMKRELRGQYKEHYQSGDGA
>NC_017672.3|WP_014650571.1|3099286_3101077_-|oligoendopeptidase-F
MPNQLQRQDVPAHEKWNLADIYPSPAAWDEDYAKIETLITTVKAFENQLTASGSLLAFLRSQEEMYRLYEKVYVYASLQLAQDTRETSSQALLDKASQLGVRVSASTAFFSPFLMSLDPEVLEGYIKEEEGLRYYERDLYEEYKYKKHVLSQEKEEVLSQLGEVIGAPRTIFNMLNNADIRFGKVHNEEGGEVPLTRGMYAKIMEHQDRSKREEAFHAFNKPYLELKNTIAATLGSSVKNNVLFSRMRGYESPLQRSLFKDDVPVSVYDNLLEATKENLAPLHHYLQVRKKALGVEDLRVYDLSVPLVTDVEMTIPYEEAYDTMLAALAPLGDEYVSVLAGARTSGWIDVRETEGKRSGAFCSGPYGTHPYVLLNHNNTFDSMFTLAHEMGHAMHSYYSDKHQPAISAQYTIFVAEVASTVNEVLLMKHYLKQNPSASLKKYLLNHFIDEFRGTYFTQVMFAEFEKRVHEKAMHGETLNSDSLSEVYEDLYKTYYGDVLELNPEVKYGWARIPHFYNAFYVYKYATGYASAFHLASRIFDGDTDTVRTYLEFLKSGRSEYPLELLRRTGVDLLQPEPIQGAMEAFAGIVKEFESTF
>NC_017672.3|WP_014650570.1|3098649_3099099_+|GNAT-family-N-acetyltransferase
MTIDIIAYQEKFHDQLVDIWYRAVRQTHAFLTEEDLEFYHGIVGGGALREVEIWVALRDHQVPAGFIGLDGTKIEMLFVDPEYHGQGIGSRLIRHAESIKGGTLQVDVNEQNDGACAFYKRYGFVQSGRSELDGAGRPFPLLHMDLRRI
>NC_017672.3|WP_014650569.1|3096550_3098518_-|hypothetical-protein
MWKKPTLAVLLGISLTLLAAAPGSALEYADTPTLPADGDHIPKTVTLLKETPYYAIPNVLLNQPEGAFSPQTVEIVEAEAHWAAFPNWWKIRTVFGDRWIKTEPGTFEVPLPSKLTLLQETPIYAKADERLKPSAVLSPQEVTVAGAEKRWFYSALNDENEQKWIQIETSWLGRQWIRLPMKQIGSLKRHSQIKFYGLTQLSTLPPMLETPGTSVPAYEGRNRILTETGEFITPLGSFYEVETTEGRRWTRTPGQVITASQETLTRSKPAALYPLPSLDSGEPVLVDPQILKVSEKIEGDPVNDYDGGWYHVKAAEGEGWFNARFSEPEDAKPVTAEVDLRADMTPLYLYPDSSLLLHNGILSPQKVQATAYWDAPKGERWFRIQTFLGDAWMVLNPLHDRIRPAGREQDQQIYGEKRYQGYYYMNNGVLPYGEEKAGYERQNELYFRSSFLAKMYHFYVSGPDADNGWTFTHESGYAFRLKAGEKKAELFWKGRNAGTALLSAVPAVSVDKEAPDLRLDSMRALFGASTETAPDHSWVSLSSSEYTLGDFKPPVRIEGNVLRLSALLYDVERPETNETPNRLKLYVIDRDADRSMAFTAQNPAAQDKLFSMNMNMALYDLTAQKTLKPGLNRLTAVFKVGERIIHEQDFDVTAQ
>NC_017672.3|WP_014650568.1|3095578_3096427_+|bifunctional-5,10-methylene-tetrahydrofolate-dehydrogenase/5,10-methylene-tetrahydrofolate-cyclohydrolase
MREPIVLDGSRVAAEIKASLAGRVERLKELGIVPCLATILVGGDPASATYVKMKANACRRLGIESVRVELPETTTTEELLEAIGRLNEDPAVHGILLQHPVPGPIDERAAFDAIAIGKDVDGVTMLGFALNTFGAAAYPSCTPAAILTILDHYGIGIEGRHAVVVGRSPILGKPVSAMLLNRNATVTVCHSRSTNLPEIVAVADIVVAAVGKPQFIQGEWIKPGAVVLDAGYNPGNVGDVDYEAACRNASAITPVPAGVGPVTISMLLKHTVEAAERAAGLR
>NC_017672.3|WP_014650579.1|3109527_3110685_+|Gfo/Idh/MocA-family-oxidoreductase
MLKIAIIGAGAISRAHIEAYLQFPDRCRIVAVSDIYRDKAEARIAEFGLEGARAVADYQELLQEDIDLVSVCTPPYTHAPISIDFLRAGKHVLVEKPMASSLQECDEMNAAARESGRILSVVAQNRFTAPLWKLKSVLDSGLMGPVVHAQVDSFWWRGHCYYDLWWRGTWEKEGGGCTLNHAVHHIDAFLWMMGRPAELQAFMSNTSHDNAEVEDLSIAMLRFPDGALAQITSSVVHHGEEQQLIFQGKRARVSAPWKVKASRSRPNGFPAADEELEAQIRELYDSLPGPEYAGHAGQVDNVLAAIETGAPVLVDGISGRSTLELILGIYKSASTGEKVTFPLQPDDPFYTREGIQANATHFYEKSASVENFQDLRIPTGAGESQ
>NC_017672.3|WP_014369820.1|3111284_3112046_-|response-regulator
MTYTVIIAEDDPLQARLLEQFCTEEGLQVFGAVSSGRRLIEEVTAGRPDLVIADITLKRQDGISAIREMIGDGLAPVVILVSGSVDPEHLLAGYDIAAVDYVRKPILRARFKQAVDRAKARVDARRRAAALPDQVNFITCKVRYRDLQFAEPQLLYAERTMLRKTKVVLSDGTHFLTSTPLHDIQAQCSERIVFSHRSYLVNTARIAAIETVPGGSRRNYEITLIGCPVKVPLTPTYYGECRQQMESFTGGPL
>NC_017672.3|WP_014650581.1|3112086_3113832_-|GHKL-domain-containing-protein
MLRRLFPSRPERRRWKPSLSMLLISLIIVLLTNSVFYYYTKNRMTRELEERLQLISDVLAVSIEHARAGEKHVEDLIGLNLRSVSIAAQSQLPADIEQVSNEELQTLSRQLMVDHITLMKRQGDDIVGYRSSDPKEIGMSTKDWRGDWFKAFNQLLDRKETQVPSGQALPNYWSGPINTSMTNPSSVDKWGYYHDGSTNYITDPFVHDTHLRSYQRDTGVDAFIREMTREDRLNAASEITVYNPPTFLKEQEQYRKDAFTWFSDREILFGSYTLKDSRDASSVREVMRTGQKQEFTTVLDGHTYLKMFIPLGLEYPAVIGLTADYEPILDWVREQQTQLTLLIGSTIFIGLLTLFLSARVMSRSRERTAESVQEVYTDKIDDLFRSMKEQQHDFNNHVAALSALVQLKQYEELTRYTEQLTEETHALNDIIQINVPALCAIVQAKLIESAQRKIRFTHDVENLSGANLGALKATDLVKVVSNLLDNAFDAVSASPRSDKHVGLTGRLADGRLQFVVANNGEPIPGAVRERLFEAGFTTKTESGDHEGLGLSIVQSILSRYKGQIEVHSSKAETRFVLSIPV
>NC_017672.3|WP_014650582.1|3113907_3114645_+|ribonuclease-Z
MKLTFLGAGDGFSVGQGHNSALLKFGGTNLCIDFPESNHAALHKLGLELNRVENVFVTHLHEDHINGLQKLAFYHGVYPLKGKPRLYVHEELLGDLWDALRHGLAYSTRGPKELSDFFEVVPVQEAFEIEGQRFELVRTVHIPGMISFGLLCAPYFYFSGDTRFDLGQIEEAAAKAKVLFYECHMQPYNLLSHTSLDELLTLPEELQRRTVLMHYIDDYLDAEKREAFHNAHALRLAELLQAYEF
>NC_017672.3|WP_014650583.1|3114886_3117481_+|glycoside-hydrolase-family-2-protein
MTITKPAYMTLSGWEFKACKDEQWLPAAVPGCVHTDLLRNGKIEDPFYGTNEKRLQWIDKEDWEYRTNFAASSEQLSQANVELVFDGLDTYADVTLNGQPILSADNMFRSWRADVKELLQEENTLRIRFRSPIQEDLPKLRALGYALPAANDQSEAGGLGDEKVSVFARKAPYHYGWDWGPRFVTSGIWKDVRLESWSGIRIRDFHIRQDQVTAEAARLTALVEVETDEAWSGELRVSAEGRQWSRDVRLEAGSHTVELAAELESPRLWWSRGLGAQELTDFRAELVSGGDVHAQETVTTGLRSAKLVREKDAHGTSFYIELNGVPVFCKGANHIPNDSFVTEVTYERYRHEVASAAEANMNMLRVWGGGIYEHDDFYRLCDEYGILVWQDFMFACSMYPGDEAFLASVRAEAEENVKRLRRHPSVVLWCGNNEMDTAWSHYDENAGWGWKKKYSPELREKIWRDYEAIFHEILPQTIRALSPETDYWPSSPMREVTGDANQHATSSSPDGDIHYWGVWHNVEPFSNYKVHIGRFMSEYGFQSFPEEKTVETYAAEEDMALVSEVMLSHQKNGRGNMLIKEYMDQYLSEPKDFRSFLYMSQVLQGEAMKTAIEAHRRRMGFTMGSLYWQMNDCWPVASWAGMDYLGRWKALQYYVKRSFRDVMLSLDENDGKVEIHGVSDLQVPLTGTLELRLLDFQGNVLRQWPASVTLAANAAGHLKSLAREEVLEGADPASVVLTARFEGSEGTTDLKEHYFLPVKDLRLEEPGVRITRRTEGEQVLFTLEADRLAKQVWLSSEAEGHFTDNFFDLLPGSPVTVAFRKRSDGGEPFAAGDPGSMQVRSMYDFIKSSAGAQEADRQAEEQAL
>NC_017672.3|WP_014369824.1|3117720_3119094_-|PLP-dependent-aminotransferase-family-protein
MLKYMELANEIEGLIETLPLREGGKLPSIRTLAQRYECSKSTIIRTLQELERQHRIYAVPKSGYYVVRSRAASEDTRTGVLDFIAAAPDPELFPYLDFQHCINKAIETYKNDLFVYGTPQGLPSLLRVVRSLLASSQIFTETDRLFVTSGVQQALSLLAAMPFPGGRRTVLIEQPGYHLMVRYLQTYGVPARGIRRTAEGIDMEELERLFRGGEIKFFYTMPRFHNPLGCSYTEDQKKQIVRLAAKHDVYLVEDDYMADFEENRRADPLFAHDPSRRVIYLKSFAKILFPGLRLGIAVLPPALAEVFSRHKKLQDIDTSMLSQAALEIYLKSGMFGRHKQRLSRSYAEKARLLQDSLQRAAGQLGDRAAFRPAPAPMIHTHLELHPGIDVPRLAARLARRSVLIGPMDQHYLEGFPRDPLLKLNVSQVKADEIERGVELIAEEISGSPLHTAKGLST
>NC_017672.3|WP_041618650.1|3119346_3120261_+|DMT-family-transporter
MAAVGNAVIIGFSFLFVKIALDTAHPLDTLAHRCTASFAVLALAAAFGWIRVKLRPREMAALLPLALLYPSLFFAFQAFGLAYSSSSEAGIIHATVPIFTALLAAAVLKEYAGVRQILFILLSAAGVVYIFVMKGAAIGSGALLGTVLILVSAGCMAAYSVLARRMTRRFTVMEMTFAMTLIGFLFFNGMSVIRHLLAGTLPAYFEPLGSLPFLGSVLYLGILSSMVTAMLNNYALSKLEASKAGVFTHLSTLVTMAAGALLLGEQLFYYHFVGAALIVLGVVGTNLPGSRKKPVSSAGRSMIR
>NC_017672.3|WP_013916109.1|3120341_3120500_+|hypothetical-protein
MMANQRNQVSKADVQSTELNKLPVEGENDTEFSAEEAAEVFSENQNANNNQQ
>NC_017672.3|WP_014650586.1|3120701_3121115_-|DUF2203-domain-containing-protein
MNNRRFTLEEANAMLPRLREDLAKLQELVKQFEGLYQELKQAKAEYLLQPAGQEGGDPFFEMEGRLDFLRIEAELFIENFTRQGVLLKMIKPGLIDFPAVVDGEEVLICWKEGEERITHYHGWHDGFAGRKPFPGAY
>NC_017672.3|WP_014650587.1|3121487_3122330_-|AraC-family-transcriptional-regulator
MQSRHPRIKHTVNSCQDIKFYYAGTEACESGQAWGPGVKDHYKIFYIHSGRGTFRTAAAEYPRSAGDGFFLVPGELYDYEADADDPWTLSWVAFNGEAVPLYLEQAGLSYDSPLFTCPPDGPTRQSLQAMIEADRNPDSFSRPLRLTAALYTFLAALLDAIQTGPVDPNRSSIKSYYVAQALDFIETNYSRSVSIEDMAHALGLSRKYIASLFKTAVGVPPQQYLCRYRMEKARELMQGSLSIKEISYSVGYSDQLIFSRMFKKTFGYAPKEYRRKSGGV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_4

3274770-3274984

Orphan

Consensus_repeat	Method
AATCTGTTGGCTAGTACAACCT	CRT

4 spacers

The CRISPR arrays of NC_017672_4

>merge|NC_017672|4|3274770-3274984|CRT
CATCTGTTGGCTAGTACAACCTGTCCCGTTTCAATCCTTCCCTTTAATCTGTTGGCTAGTACAACCGCTTTCGGGGAGGACGCTCGCTGCGAATCTGTTGGCTAGTACAACCTTTATTGGATGTATTCGCTCCGTGCGAATCTGTCCGCCAGTACAACCTGGTTGTACCTGGATGCCGCTGGAAAAAAGCCTGAATCTGTTGGCTAGTACAACCT

>NC_017672|4|2|3274770-3274984|CRT
CATCTGTTGGCTAGTACAACCT	GTCCCGTTTCAATCCTTCCCTTT
AATCTGTTGGCTAGTACAACCG	CTTTCGGGGAGGACGCTCGCTGCG
AATCTGTTGGCTAGTACAACCT	TTATTGGATGTATTCGCTCCGTGCG
AATCTGTCCGCCAGTACAACCT	GGTTGTACCTGGATGCCGCTGGAAAAAAGCCTG
AATCTGTTGGCTAGTACAACCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014650675.1\|3268110_3268707_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NC_017672.3\|WP_014650670.1\|3265048_3265651_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NC_017672.3\|WP_014650683.1\|3279037_3280480_+\|glycoside-hydrolase-family-1-protein	unknown	unknown	gnl\|CDD\|225343
NC_017672.3\|WP_014650676.1\|3268706_3269390_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_017672.3\|WP_016362561.1\|3267489_3268110_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|226472
NC_017672.3\|WP_014650679.1\|3271850_3272420_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_017672.3\|WP_014650681.1\|3277536_3278601_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_017672.3\|WP_014650672.1\|3266025_3266691_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378968
NC_017672.3\|WP_014650687.1\|3283448_3285098_+\|alginate-lyase-family-protein	unknown	unknown	gnl\|CDD\|377511
NC_017672.3\|WP_128759032.1\|3282615_3283101_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014650684.1\|3280566_3281544_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380509
NC_017672.3\|WP_013916270.1\|3286462_3286783_-\|YnfA-family-protein	unknown	unknown	gnl\|CDD\|235016
NC_017672.3\|WP_014369936.1\|3286963_3287311_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014650680.1\|3275563_3276967_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014650685.1\|3281835_3282366_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NC_017672.3\|WP_014650688.1\|3285337_3286342_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|366353
NC_017672.3\|WP_014650677.1\|3269379_3270468_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_017672.3\|WP_014650678.1\|3270770_3271649_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NC_017672.3\|WP_013916257.1\|3272644_3273988_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NC_017672.3\|WP_014650671.1\|3265703_3266042_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014650675.1\|3268110_3268707_+\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.84579e-30
NC_017672.3\|WP_014650670.1\|3265048_3265651_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	1.47343e-140
NC_017672.3\|WP_013916270.1\|3286462_3286783_-\|YnfA-family-protein	gnl\|CDD\|235016	PRK02237, PRK02237, YnfA family protein.	1.60925e-42
NC_017672.3\|WP_014650676.1\|3268706_3269390_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.68316e-91
NC_017672.3\|WP_016362561.1\|3267489_3268110_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|226472	COG3963, COG3963, Phospholipid N-methyltransferase [Lipid metabolism].	1.0226e-36
NC_017672.3\|WP_014650679.1\|3271850_3272420_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.74932e-17
NC_017672.3\|WP_014650681.1\|3277536_3278601_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.89677e-42
NC_017672.3\|WP_014650672.1\|3266025_3266691_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|378968	pfam12840, HTH_20, Helix-turn-helix domain. This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.	2.10653e-08
NC_017672.3\|WP_014650687.1\|3283448_3285098_+\|alginate-lyase-family-protein	gnl\|CDD\|377511	pfam05426, Alginate_lyase, Alginate lyase. This family contains several bacterial alginate lyase proteins. Alginate is a family of 1-4-linked copolymers of beta -D-mannuronic acid (M) and alpha -L-guluronic acid (G). It is produced by brown algae and by some bacteria belonging to the genera Azotobacter and Pseudomonas. Alginate lyases catalyze the depolymerization of alginates by beta -elimination, generating a molecule containing 4-deoxy-L-erythro-hex-4-enepyranosyluronate at the nonreducing end. This family adopts an all alpha fold.	1.73562e-36
NC_017672.3\|WP_014650688.1\|3285337_3286342_+\|C40-family-peptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.70877e-23
NC_017672.3\|WP_014650684.1\|3280566_3281544_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380509	cd06286, PBP1_CcpB-like, ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. This group includes the ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. Catabolite control protein B (CcpB) is 30% identical in sequence to CcpA which functions as the major transcriptional regulator of carbon catabolite repression/regulation (CCR), a process in which enzymes necessary for the metabolism of alternative sugars are inhibited in the presence of glucose. Like CcpA, the DNA-binding protein CcpB exerts its catabolite-repressing effect by a mechanism dependent on the presence of HPr(Ser-P), the small phosphocarrier proteins of the phosphoenolpyruvate-sugar phosphotransferase system, but with a less significant degree.	2.04577e-117
NC_017672.3\|WP_014650683.1\|3279037_3280480_+\|glycoside-hydrolase-family-1-protein	gnl\|CDD\|225343	COG2723, BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase [Carbohydrate transport and metabolism].	0
NC_017672.3\|WP_014650685.1\|3281835_3282366_+\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	1.89655e-06
NC_017672.3\|WP_014650677.1\|3269379_3270468_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.14497e-50
NC_017672.3\|WP_014650678.1\|3270770_3271649_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	2.20621e-30
NC_017672.3\|WP_013916257.1\|3272644_3273988_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	4.2356e-05

>NC_017672.3|WP_013916257.1|3272644_3273988_+|replication-initiation-protein
MPRGKKTQDAGKAGTQQKSLAGKLIRELEMKGEETEAASSIDEQDTKPRSNTKPKVKSSIIRLADKAEAMAEKLIRQIEQSTNPDDVTSVEDLLKESASKLDSTKSYLTKDITEASVYLLQKLSQIVSETSSVVDNLSLTKNQYARQIIKLAKEMRERKKTQPMELNLMASNPFFTGIPNSYKEKVKETGLAEVVKNGTKTLEYQNSEGLYLSEFDKRVFTALTSIWVDQNCKQIFKFTEFELLRRLEMNPKGGMQHKRVRDSLRALTTTQIVIKEFYEKKNANRIVTSKFHLVASETTIEEYSKDDGKLQSREYQFQFADQIRQSFQDGYTTLISLGILDTLNTKTSRELYQLLCTIRDMAPQEQFKYTVEAGAFDVSLTEISEYMHLANNEYDNRRNILKACEELKEVYVLQDYVKLGTGRSCSAIRFYPGTLLKKEEVKVLTQG
>NC_017672.3|WP_014650679.1|3271850_3272420_-|TetR/AcrR-family-transcriptional-regulator
MSTASTSSRQRLLDTASDLFYREGIRAISMDTIVERSGVSKATLYRHFPTKDELISAYLKAHDHHIWEHFDEAVAKHEGSPKDQLLALIDAIAELFQPEYYRGCPFLNAFAEFSDPHHPAHRLAMEYNHALRSRLSDLSQKAGVTDESWPDQLLLVINGAYSSVPVLGLTGSAAQLKKLTAQMIHQYVH
>NC_017672.3|WP_014650678.1|3270770_3271649_-|NAD(P)-dependent-oxidoreductase
MSEVSIIGLGPMGTALAQTFLKNDKRITIWNRTASKAESLVRQGAVLASSAASAINASPITIICVANYGSSASLLDTQEAASVLAGRTLIQLSTGTPQEARNSELWARERGADYLDGAIQAWPSHIGAPETVILFSGSSTAFQTSEPLLRILAGNSIYLGEPVGSASAQALAVISYLLGTWLGFAHGAHILESEHLPVDSFGSMIAAIAPLLGEEAKHQGKVIQTGKFGNPESSLQTSADSVERLLQQATEAGINSDFPRFALPLFAKAAAAGYGDEEVSAMIKILRGGSAS
>NC_017672.3|WP_014650677.1|3269379_3270468_+|HAMP-domain-containing-histidine-kinase
MKNDRFHPKRGRRSIRVGLIWTFVFSLVIAIFSFNIVLRLAFLYVDRFQLGFYFYNLPIVAFVLAFIISFYQLTRRMVNYLIALADGLQIISEGNLDYRVPIIRKDELGQVAMNINLMTERLQRQMEKERKIESSKMDLITGVSHDLRTPLTSIIGYLELLRTDSFQNRDEYTRFVQNTYSKAVHLKKLIDDLFEYTRLTTPDMQLDLRPIDVHQLLEQMLFEFEPLAQENGIQLVKEIDHPPVIALMDSGKFARAIDNLLMNALKYSVKPGTIQILLRTDPQRFYIEIENKGQPLTEEQEDKLFDRFYKVDHSRSSEGIQNGTGLGLSIARNIIERHGGTLTLTHRNGIFVFTIGADLNGT
>NC_017672.3|WP_014650676.1|3268706_3269390_+|response-regulator-transcription-factor
MVTVLVVDDDPEIRDVIHVYLRNEGYSVLEAADGLEALDAVSSNSVHLVILDVMMPRMDGIKTCIKIRETSKVPIIMLSAKEEDMDKITGLITGADDYMTKPFNPLELLARVKAQLRRQTFTEKEPSDSLIRIRDLMVDKAKHSVSMRGNEISLTPLEFSILELLASHPGQVFSANKIYESVWNEPSGYSDNTVMVHIRNLREKMEDRPREPLYIKTVWGVGYKLEK
>NC_017672.3|WP_014650675.1|3268110_3268707_+|DedA-family-protein
MNYDTLIHSIAQFGYAALFLALWLGIVGMPIPDEVIVMTGGAVGKIGLLHSIPAFLVTYLGVISGLSLGYILGRFFGSPVLHKLRRKQKWKKHIQTSEHLLTKYGDFALSFSYFIPVVRHIVPYLVGIHQMPFRRYMLYSYTAGLVWTSVFFVLGQFAGSHVEILGTMIYRYSIYAGLALLLGIFLYVTLQIRKRSNA
>NC_017672.3|WP_016362561.1|3267489_3268110_+|methyltransferase-domain-containing-protein
MSRLVNEENKGNGEIHLTSNANQSVMFLQQFIRNPKQVGSVIPSSRFLASKMVQSVPWNDVTTIAELGSGTGAVTRFIQRRVTGSTNVLLFEMDEKMRSDLQANYPSFTCHSNACHLTKMMIEKGIHQLDCVISGLPFFNFKSDLREAILHQITEALKPGGRFIAFQYSLQMKKHLSEKFLIDKIDFVPFNFPPAFVYSCRKKEGM
>NC_017672.3|WP_014650672.1|3266025_3266691_-|helix-turn-helix-transcriptional-regulator
MTPHEPILESVLIDSPEQAMVLLNPLRAEIAARLSEPGSAAEVARAIGEAPQRINYHLKALEKAGLVRRVGSRQVRNLVEVLYQSIARTFVLSERLGMKPETARKLKDQGSLAHLIGTADRIKQDALLLMEHSDEGEEVPSATLQFQVELATPERRQAFVEEYARLVQELTAKYGGDAAEGAYQVVVAVYPEASGRAAAPEGAQEKPAPKKRRKRIDGTQA
>NC_017672.3|WP_014650671.1|3265703_3266042_-|hypothetical-protein
MEHKPEKEFTAGTEEQRPGNAPQPAVVWESKSTAETAPPDRGQVSDLSAYRERKEAAAPDREATVTRWALPGRQKGDPAQWLIMVSSGFGAAPAVIRSGRGGAGDVKACLAA
>NC_017672.3|WP_014650670.1|3265048_3265651_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNYIPMVVEQTGRGERSYDIYSRLLKDRIIFLGSAIDDTVANSIIAQLLLLSAEDPDKDIHLYINSPGGSTTAGLGILDTMQYIKPDVSTICVGMAASMAAVLLVAGAPGKRFALPHAEVMIHQPHGGSQGQASDIHIHAQRIVQTRELLNRIIAERSGQPFEKIERDTDRDYFMTAPAALEYGIIDKVLHSVQGTGAAS
>NC_017672.3|WP_014650680.1|3275563_3276967_+|hypothetical-protein
MIYKDTYHLMMNSLSSTEIDACLAMLLHLDWENRLRIEPEHLARQIGTTSKYMGDILRKFLRDKKVLSKDRKDDTYAFRYGQSSLQYDERTTKYGKKFSLYYTPQFRSLSLNAKRLLIMALFRISETRDTEFHIPRLRLIRRSGQEGRLPLTGTQLLDVLQELRDAQIPGLSSAEIVQFQGEANVVIRFSDDIQQAYLENHTEMNLVKRELFKLGLHRLVPSDELCHALLSVGYHLFKSMLEADFAMNRREGEAEERRQGILRTARHMYNTALARLAASFPAKRMELTNKDKLAAYFSAIVHEVMTQEMASCSYQVLQQESLLDYYMDKTKQEGITYGGPEVKALVLHIDGMKRMAAVLETVCQQWLLSRVATLSKDLSEAARSTQDQERILDRRGWTSIEEGKAQLRKLLKHEEELLAAMRAHVGSGVRVPARVLEEAMERYFVEIQTRAADLAAKNSRMNTDKTA
>NC_017672.3|WP_014650681.1|3277536_3278601_+|serine-hydrolase
MDHVIEEVMSDPKVLRWANRPAHQLTVGVLHPSGRKIWSSGGESGETDGTGRAYEIGSITKTMTGLMLAAGEQQGLWSRSDRLSDVNPDLAASPFAKQTTLLDLVTHTSGLPDVPGNFKASITDRLNPYANYDEARLIEAVLAEKPKSGSRHRYSNYGFGLLGWLLSRRLGTALDDALTRQVFHPLGMPDTYAGWRTPAPAQLLPVYNSKGKALPPWDFHDAMGGAGAVRSTAADMLNYLEAHVHPDSHSFSPAVEEGLKEHYAIMPSRGIGIGYGWMRYREKDGTVTHWHNGGTYGSSSFIAFNRSKGAGVVILSNNGSTMWSQLAPMLGLRLLSVDALATRLTKKLFAASAG
>NC_017672.3|WP_014650683.1|3279037_3280480_+|glycoside-hydrolase-family-1-protein
MIHTQVRPFPQDFLWGSASAAYQIEGAWNEDGKGPSVWDVFTKIEGTTYKGSNGDVAMDHYHRYREDIALMAEMGLKAYRFSVSWPRIYPSGHGEENEAGLQFYDNLIDELLAHGIEPVLTLYHWDVPQALMDEYGAWESRRIIEDFDNYCITLFKRYGDRVKYWVSLNEQNYNTNHGFITAMHPPGVKDRKRFYQANHHAFLANAKVIDSFRHYVPHGKIGPSFAYSPAYPASSKPEDLLAFENAEEFTNYWWLDVYCLGQYPQIPLRYLEEQGLAPVFEEGDLELLRRGRPDFVGVNYYQTITYEKNPLDGVAEGRMNTTGQKGSNQSTGMPGLFKTAANPNLETSNWDWAIDPIGLRIGMRRITSRYGLPVFITENGLGEFDKLEADDTVHDDYRIAYLRSHLLQCQQAISDGVELIGYCSWSFTDVLSWLNGYQKRYGFVYIDRDETDARSLRRIKKLSFHWYREVIRTGGEHLLK
>NC_017672.3|WP_014650684.1|3280566_3281544_+|LacI-family-DNA-binding-transcriptional-regulator
MANIREIAKAAGVSVATVSRVLNGHPYVSAEKRRRVDEAMRRAGYSPNSNAVHLSTGRTGMVGVILPFSHHPYFHALLGGLMEEALKHQYTALLCQTNYEAGEERRYLQMLRTKQVDGLILCSHELPWPEIAAYAADGLLVACEPVRQEGISCVYTHHYEAFLTGMRYLIRRGHRNIGFCIGRRDSESSRQRYAAYADALREIGRPVQPEWIFEGCTDLRDGMRVMDRIAAMESRPSALLVTGDEAAAGVLARSRQLGIAIPGELAVVGFDNQPISEALQLTTIDQHLQEIGRQAFGAFYHGIVQPGAAPRRMEVPFALVERTSV
>NC_017672.3|WP_014650685.1|3281835_3282366_+|DoxX-family-protein
MLTRFLRDNVYAAGLLLILRLYVGYQWFTAGFHKLTGGFDAAGFLKGAIAKPVLDKATGELVYPTFAAFLQNFALPNVKVINFLIPAGETLVGLGLILGALTTAAAFFGLLMNFMFLFAGTVSTNPWLVLLGVIVLMAGTNAGRFGVDRYLMPLLRKLRRQGGDEAGRRKGIPAKA
>NC_017672.3|WP_128759032.1|3282615_3283101_+|hypothetical-protein
MNQLILWSLLIIPWFSLLFMDTTKLRRFFPVALLVTVINTLFYQAAYHYRWWRESGLFGWDNVIPVPWIYGAYLVATIWIFRFTYGRFWLYLLVNVVLDAAYMFAWYPVQQRLGLAEQGNLPPWASYAMMLGIAVAIYLFQKWLEGDELEVQLGGRRKQAR
>NC_017672.3|WP_014650687.1|3283448_3285098_+|alginate-lyase-family-protein
MRNQGRRKLPVLAAAGLAAGLVFSSAAAAYPHPGGVHSEAQLASAKRNIAGGLQPWADAMKELIPRADFYLSEPPSASADFHVPGYYEDPAGHTGASEVLHTDVRAAYASALAYRLTGRTAYAEKAKAILNDWAFRNTAVSGTDGPLVMTYSGVGFIHAAELLRDYSGWSEADKTAFSNWLTNVYLARAANPIKTRSNNWGDWGIYGAMAAYYYKDDPVLLNAEITRLKNKIDSSIAADGSMPHEAGRGASGLWYTYFALAPMTAAAQIAKEAAGIDLFQWTSPGGRTIKQALDYLLFYMNRPDQWPYGANPRMPVSDEEWGYNLFEAMSDYYDEPAYKSFASVKGPIMYLASHFAWNFPSVTKGGLRLVDEKFDVLTSTAAPRGWTVSKAANTSAVVWNTPTAADKSLKIWDTSTSGTASAVKVFPDQYGIIEAEWKFMYMALFPNARFGLKHAAVYAAELLTTASGLIYRSGTGSDIVLQTLSPDAWYTVKLIANPASDKTDVYVNGQLKASGVPFRSTVSALDRIEFAGGSGETGTFYIDQVKIMN
>NC_017672.3|WP_014650688.1|3285337_3286342_+|C40-family-peptidase
MKRIITAASAALIAGVFALPQGQAQAATTSTIVSDVSFRKAPDTDAARIRYLQEDEKVTVVSKVNDYWYKVTDKNGVTGYVSSSSKYISAPRTTSTGTAAASNTGKIVSGVSFRKAADTDAARIRYLQEGETVTILDKVNSYWYKVKDKNGVTGYVSTSSKYISASYKETASAAPAGTTSGGTSSSTTSTQKVEKVISAGMKYLGTPYEYGSDRSTVATFDCSDFVRQAFKDALGVTLPSNSRTQADYVREHSSRIVTDIDNLKRGDLVFFMSYRGSSLSAYSGIDKSAQRITHVGIYLGDGKMLNTWGTGGVKVDTITGRHWEGRFIFGGSAL
>NC_017672.3|WP_013916270.1|3286462_3286783_-|YnfA-family-protein
MAVVLFLLAGLAEIGGGYLVWLWLREGRSLWLGLTGCLVLVAYGIIPTLQSFPSFGRVYAAYGGVFIVLAVLWGWLIDRKTPDLYDWIGAVVCTAGVAIMLWAPRG
>NC_017672.3|WP_014369936.1|3286963_3287311_+|hypothetical-protein
MNLMYGFGLLAAGLSIINAIFSYQAKAIDPGFGPMLWFQLRMLPLMFFSNVMIGYGVKYLYRAFQSLTFALTVSKGLEILVCVVMGYLFLKEVPTWRTYAGLGVVVCGFVLTRWK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_5

3600542-3600682

Orphan

Consensus_repeat	Method
GCAGGCGGGCTAACACGGATTTTCCGTG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_017672_5

>merge|NC_017672|5|3600542-3600682|CRISPRCasFinder
GCAGGCGGGCTAACACGGATTTTCCGTGCTGCCGGGCCCACTCTGTGCTTTTTTGGCCTTGTGCAGGCGGGCTAACACGGATTTTCCGTGTTGCGTGGCGGAAGCAGCGTGTTTCGAGCCGGTTAGCACGGATTTTCCGTG

>NC_017672|5|3|3600542-3600682|CRISPRCasFinder
GCAGGCGGGCTAACACGGATTTTCCGTG	CTGCCGGGCCCACTCTGTGCTTTTTTGGCCTTGT
GCAGGCGGGCTAACACGGATTTTCCGTG	TTGCGTGGCGGAAGCAGCGTGTT
TCGAGCCGGTTAGCACGGATTTTCCGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014370088.1\|3606965_3607178_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014370087.1\|3605770_3606940_+\|Ger(x)C-family-spore-germination-protein	unknown	unknown	gnl\|CDD\|274338
NC_017672.3\|WP_016362588.1\|3610261_3611038_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014370089.1\|3608497_3609292_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213260
NC_017672.3\|WP_014650832.1\|3598043_3599771_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_017672.3\|WP_013916604.1\|3604322_3605771_+\|spore-germination-protein	unknown	unknown	gnl\|CDD\|377020
NC_017672.3\|WP_013916601.1\|3600938_3601286_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227255
NC_017672.3\|WP_014650833.1\|3601423_3602944_+\|carboxypeptidase-M32	unknown	unknown	gnl\|CDD\|341054
NC_017672.3\|WP_041618286.1\|3592191_3593226_+\|nucleotide-binding-protein	unknown	unknown	gnl\|CDD\|378409
NC_017672.3\|WP_041618284.1\|3589265_3591659_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|226229
NC_017672.3\|WP_013916600.1\|3599923_3600517_+\|carbonic-anhydrase	unknown	unknown	gnl\|CDD\|239474
NC_017672.3\|WP_014650828.1\|3595794_3596073_-\|YxcD-family-protein	unknown	unknown	gnl\|CDD\|313933
NC_017672.3\|WP_014370086.1\|3603210_3604326_+\|endospore-germination-permease	unknown	unknown	gnl\|CDD\|281794
NC_017672.3\|WP_013916609.1\|3609284_3610133_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_017672.3\|WP_013916607.1\|3607364_3608387_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223787
NC_017672.3\|WP_014650831.1\|3597312_3598047_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_017672.3\|WP_016362587.1\|3596719_3597316_+\|DUF309-domain-containing-protein	unknown	unknown	gnl\|CDD\|377120
NC_017672.3\|WP_014650829.1\|3596097_3596535_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226830
NC_017672.3\|WP_041618288.1\|3593720_3595643_-\|glycoside-hydrolase-family-18	unknown	unknown	gnl\|CDD\|119353
NC_017672.3\|WP_014650826.1\|3593222_3593456_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014370087.1\|3605770_3606940_+\|Ger(x)C-family-spore-germination-protein	gnl\|CDD\|274338	TIGR02887, Spore_germination_protein_B3, germination protein, Ger(x)C family. Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination].	1.88724e-90
NC_017672.3\|WP_014370089.1\|3608497_3609292_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.27838e-108
NC_017672.3\|WP_014650832.1\|3598043_3599771_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.50287e-66
NC_017672.3\|WP_013916604.1\|3604322_3605771_+\|spore-germination-protein	gnl\|CDD\|377020	pfam03323, GerA, Bacillus/Clostridium GerA spore germination protein.	0
NC_017672.3\|WP_013916601.1\|3600938_3601286_-\|hypothetical-protein	gnl\|CDD\|227255	COG4918, COG4918, Uncharacterized protein conserved in bacteria [Function unknown].	2.13144e-24
NC_017672.3\|WP_014650831.1\|3597312_3598047_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.5704e-81
NC_017672.3\|WP_041618286.1\|3592191_3593226_+\|nucleotide-binding-protein	gnl\|CDD\|378409	pfam10137, TIR-like, Predicted nucleotide-binding protein containing TIR-like domain. Members of this family of bacterial nucleotide-binding proteins contain a TIR-like domain. Their exact function has not, as yet, been defined.	1.1568e-24
NC_017672.3\|WP_041618284.1\|3589265_3591659_+\|diguanylate-cyclase	gnl\|CDD\|226229	COG3706, PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms].	3.61051e-59
NC_017672.3\|WP_013916600.1\|3599923_3600517_+\|carbonic-anhydrase	gnl\|CDD\|239474	cd03379, beta_CA_cladeD, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	9.91693e-54
NC_017672.3\|WP_014650828.1\|3595794_3596073_-\|YxcD-family-protein	gnl\|CDD\|313933	pfam10850, DUF2653, Protein of unknown function (DUF2653). This family of proteins with unknown function appears to be restricted to Bacillus spp.	1.50603e-38
NC_017672.3\|WP_014370086.1\|3603210_3604326_+\|endospore-germination-permease	gnl\|CDD\|281794	pfam03845, Spore_permease, Spore germination protein.	1.47171e-42
NC_017672.3\|WP_013916609.1\|3609284_3610133_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	9.91921e-61
NC_017672.3\|WP_013916607.1\|3607364_3608387_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	7.24301e-44
NC_017672.3\|WP_014650833.1\|3601423_3602944_+\|carboxypeptidase-M32	gnl\|CDD\|341054	cd06460, M32_Taq, Peptidase family M32, which includes thermostable carboxypeptidases TaqCP, PfuCP and FisCP. Peptidase family M32 is a subclass of metallocarboxypeptidases, distributed mainly in bacteria and archaea, whose members contain a HEXXH motif that participates in coordinating a divalent cation such as Zn2+ or Co2+. It includes the thermostable carboxypeptidases (E.C. 3.4.17.19) from Thermus aquaticus (TaqCP) and Pyrococcus furiosus (PfuCP), which have broad specificities toward a wide range of C-terminal substrates that include basic, aromatic, neutral and polar amino acids. These enzymes have a similar fold to the M3 peptidases such as neurolysin and the M2 angiotensin converting enzyme (ACE). The keratin-degrading extremophilic eubacterium Fervidobacterium islandicum M32 carboxypeptidase (FisCP) plays an important role in cellular metabolism, and significantly enhances the degradation of native chicken feathers. It has been shown to mainly cleave the C-termini of peptides with a basic amino acid sequence. Novel M32 peptidases from some eukaryotes: protozoa Trypanosoma cruzi, a causative agent of Chagas' disease, and Leishmania major, a parasite that causes leishmaniasis, have been identified, thus making these enzymes an attractive potential target for drug development against these organisms.	0
NC_017672.3\|WP_016362587.1\|3596719_3597316_+\|DUF309-domain-containing-protein	gnl\|CDD\|377120	pfam03745, DUF309, Domain of unknown function (DUF309). This domain is found in eubacterial and archaebacterial proteins of unknown function. The proteins contain a motif HXXXEXX(W/Y) where X can be any amino acid. This motif is likely to be functionally important and may be involved in metal binding.	4.66556e-21
NC_017672.3\|WP_014650829.1\|3596097_3596535_-\|hypothetical-protein	gnl\|CDD\|226830	COG4395, COG4395, Uncharacterized protein conserved in bacteria [Function unknown].	2.37327e-07
NC_017672.3\|WP_041618288.1\|3593720_3595643_-\|glycoside-hydrolase-family-18	gnl\|CDD\|119353	cd02874, GH18_CFLE_spore_hydrolase, Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.	1.8272e-64

>NC_017672.3|WP_013916600.1|3599923_3600517_+|carbonic-anhydrase
MSGLLGDILEFNRSFVEQKKYEPYLTSKFPEKKIVVLTCMDTRLVELLPACMNIKNGDVKMIKAAGGFVSTPFGGIMRSIIVAIYELGAEEVYVIGHYDCGMSSVNPEKMKDKFVARGVKSDTLQTLEYSGVDINRWLKGFNDVTDSVKGSVSLINHHPLVPDIPVHGLVIDPVTGRLDLVVDGYAKKTEDSASAGE
>NC_017672.3|WP_014650832.1|3598043_3599771_+|HAMP-domain-containing-histidine-kinase
MIGRFLGRWMRSLYIQIFLSFLATCILFFGGLALFWNSYFTDFFYKDKKELLRSRSAEVVKLLPSYEEGSVSNREMRFGTRIIARGFNGMIWLVDAKGTVLSGSSEREGSTLPEELKGLFADGLNGGSGFYAATLKGEPFPVGGGSVVPPFGQGGGGGGGGSGGSRSGSPPENNAAAGTGTDPGRQEAGRSGAAPAETTAAAPGAAPGNPVPLPDRLGLVGPADESLLVYYTPAELHGEPIVILMLMPALEVSEALSAVRLNILVPLLFSMIAVGAILFILSRKLAGPLQRMSRAALEVADGDFTTRVPVTSRDEVGELAGSFNFMVDQLQQWEDTRQEFLAHVSHELRSPLTSLRGLIVAMNDGIIPPDKVSHYLRICDGEVQRLQRLVNDLLDLARIQNGTDVFRLRPVKVLEHVRQTLELVRPDAEEKGLALVMSAPSRSAAELWCELDPDRFSQVLLNLIYNAIRFTPEGGTITVELQAEEGEAAVYVRDTGIGMSEEELSRIWDRFYKADASRTGGAEGTGLGLTIVKHLVGGMNGLITAESVPGEGTAFRVAFNLHTPEHRGPGGGTEA
>NC_017672.3|WP_014650831.1|3597312_3598047_+|response-regulator-transcription-factor
MSGEVSGRPPVILVVEDERHIAEVIRLYLEHAGYEPILRERGDGIAEAVPTVAPDLILLDVMLPGLSGFEICSRIRELPEPAGSTPVIFLTAKGESIDKLRGFQLGVDDYIVKPFDPNELVARIKAVLRRAQAPRQAPSPEAGQKTLRVDNLTVDLEQYKVTVDGSRVELTAKEMELLYFLASSPGRVYTREDLLGFVWSFDFNGGTRTVDAHVKNLRKKLGSGYRWSIQTMWGIGYSFEVREA
>NC_017672.3|WP_016362587.1|3596719_3597316_+|DUF309-domain-containing-protein
MMTDNSNGTADSPGLSGNGGRRYPDAYVRYLVHFHAERDYFECHEVLEEYWKEHPGDADGEAYVGLIQLAVSLYHQRRGNLAGAVKMLSGAIRRLGSGAAAELGIAEAELQRLMGARLVELGDPAAFVYRDLDIPLADQALLQACEETSGATWERWGQPSDLSDRYLIHKHTLRDRSGVVEERERQRKQRQEKRGEGA
>NC_017672.3|WP_014650829.1|3596097_3596535_-|hypothetical-protein
MWKKLSMILMACTIAFSFSATGTADAAKYKSPKKSYAPSNGATTTTPNAGVNKADPAASKSPAAGAAATPQKRGFFSGGGLMKGLMIGGLAGLLFGGLFGGLGILGNILGLLVNVIAIVALIAIAARVFVYFRDRKKFKEEPRRY
>NC_017672.3|WP_014650828.1|3595794_3596073_-|YxcD-family-protein
MRLNEQDIINAICLHTAERKGIQPTQVEVSLEYDDDLGFSAEVTAEGRSQILIAANMLEAIERYLFQHQGVRVFRDQIHLRLEDEIVADISR
>NC_017672.3|WP_041618288.1|3593720_3595643_-|glycoside-hydrolase-family-18
MKRKTLISMSLFAMLFSSAGSVHAADKTTKYRVYQDQQVLMETASYAEAEAYARWFADSRVEEIGSRKWLWHNYPKYRVYQNGASLPQWKFASLEAAVAEASKWGHASVRDLESGGWVWNNYPKYRLYQGEITLDAWAFPTLEAAVAEARRWGNVHIIDLSTHGWVWDNIPAGRKAELRQGPKLYQLYQGSYTSEAWTFASLEDAVNASLYWSNSEVRRTDSGKVVHSNVKPYKVYQFDKEIGSFLGLEQAIAYAQAYDHTRITERPEGSSTARTIWNNYPYYQVYQNNQWIADFQTIGGALAYASRYSSASIRLYDDGSVIWDNLKDLQFWGWNGSSSDTTIRSHVSGTQGLDVVSPTYFQLQDTSGGLADTSNAATVAWLKEQGYSVHPLVANQFDSKLTTGFLASTEARAKFIDALVSRAVKLGVDGLNIDFESVSGSDRAAFTKFMEELTAKAHEQKLTISVDLPRGSAKWNAKTAFDHEKLAGIVDYVITMTYDQHWKGSTEPGSVAGLPWVEEGIREFLAYGIPRDKLIIGIPFYVREWKIDAAGKLESNRALLMKDLPALIESKKAVRTYDARFGQDKVEYTENGARYVFWMEDESTVKARIDLAKKYDLAGVAAWRLGYDPSSLWNMMLQQK
>NC_017672.3|WP_014650826.1|3593222_3593456_+|hypothetical-protein
MNRNSRPERQGTPSQSRISRSLPGFKSLRTDKRGAYQSVRRRSRNGIIFIGPSVEGADQEYVKVLSGEVDRKKPSFA
>NC_017672.3|WP_041618286.1|3592191_3593226_+|nucleotide-binding-protein
MSTPMKTKPNTFIGSSREAMELASAMHAQLSYDTQVTPWYAGAFRGGEYTMEALERELNDNDFGVFVFAPDDVALHRGQYVFITRDNTLFEMGLFWGRLGRSRVYAVIPAEVRERDDLIQGETVKQFHILSDLQGLTLLRYEIRTDDNFEAAVSVACREIIRNIRQQGAYQDPRELLLAKEAELLQKQSLLHFFWEYNRHVTAADAAEKYTALSEAVRNSILPPDGFRVTGAAFWQKQAGEGIGQVGGNVGKGRFFPFDANRQKSEGDQIIYVLDVFLSGKWTFFKRQELAQVYVLCYPLGTEHALSVHFAGRDELTDDRLTRTVTDNIDLLRTIDHLIGGDSV
>NC_017672.3|WP_041618284.1|3589265_3591659_+|diguanylate-cyclase
MNLLTSMKNQLRLGGLLTIVLVTLSYSSITVFTEGQRLEQQGRRSLETNLSLKAQYIERWLESRLTDLRLLALMREFKQADQAQAGALLRLSRDTWGIFDKIHFVDRGGELAASSDQGIQDWVPVIDRPYFLDALNGQEHISDLTMAKSTNEPLIFFSTPVRDESGTVTGLLLGSVKLEVIDRLLATLQPPTPGSDSYLVDLGGRMLSDFRHTQELQRLGRGPGESRLAIDTEIYQDALKHQLPEESYRDYKGQEVYGSYVWVNHGKWLLVGEVDQKMLFRGMFHDLLNQAVLGFFIILAAALFFVKIVEHRLAGTLKVLLERAQSIRRGSYGKPQPDSQFEKAPQEYRILMDAMNEMAETVRCKIDLLEASEQKFKSLFDHHLHAVCTFDLQGHYTSANAVCLSDTGYTLEEFISLRYDKLLHPDDWGRLETALGRLKNGQADEFKITVITKEGQLRQLYNSVIPIYSGSDITGAFCVAKDITVQLQAEARLRASEEKYRFLTESSSDMISVHDRGTVYRMVTPASSALFGYEPEELYDRSAFDFIHPEDLQSVGLTHQKIWEAAAVESVTYRMRRKDGTYVWVESKSRKVHSESEGETVVVVTRDISERKQAELALTEVNKKLLHQAEQDGLTQIPNRRRFDNTLRSEWRRAARTESPISMILLDIDYFKAYNDTFGHLSGDECLKKVAAILRDNLLRETDLVARFGGEEFAVLLPHTDLEGALVVAEHLRKAVEAAGLPHPKSRIGEVVTISLGVASLKSPLPHEPTELIEQADRALYDAKKQRNHVEAYTATA
>NC_017672.3|WP_013916601.1|3600938_3601286_-|hypothetical-protein
MSIQFTEAAQSAIAKVRGSQGYIKLAYDSEGCGCSVSGVPTLWIVDEAGPFDLVKQGEPFDVLMEQKHEVFFEDAMKVDYQEIGHIFSLKSSGQIYNARMQLVDKRKQPAGRQAE
>NC_017672.3|WP_014650833.1|3601423_3602944_+|carboxypeptidase-M32
MKTLSRPIMWEQFKKYLKKMKSYEEAIGLIYWDMRTGAPKKGIENRSEVVGELSGELFKMSVSDEMGAYIEHFTSPEGSKDLSDTDRRIVRECQREYDRSRKIPPDKYQAYVVLTSQAEAAWEDAKHSSDWDSFRPYLEKIVQTNLEFVELWGYEGHKYNTLLDMYEPGMTVEKLDEVFGALRAQVVPLLAEIQKSAHQPDTGFLKQTFEKEKQKRFSLYILEQMGYDFEAGRLDETVHPFATGLNPGDVRITTRYLTDDVNSALFGTIHEGGHALYEQNISEELLGTPLCTGTSMGIHESQSRFWENVIGRSRPFWSRYFGEVQKTYPGQFDDVTAEGFYRATNEVKPSLIRIEADELTYNLHIMIRYEIEKALFSGEAKVADLPELWNAKYREYLGIEPSNNGEGVLQDVHWSGGAFGYFPSYALGNMYAAQFTRALQKDLGDIDALVSEGNLLPIKAWLTDKIYKYGKSRTPNELVLEVTAEELNPQYLVDYLRTKYSDIYKL
>NC_017672.3|WP_014370086.1|3603210_3604326_+|endospore-germination-permease
MEESRISRTQALMLVISSITVTGHLLFIPVILNHASRDSWLSLLCAAVPALLAAYLTARLSQRFPGQSPVEYARTILGRWLGSAVSALFIFYLFHDATLSIRGFGEFFTSAITPRTPILVYMTAIIILAGYAVRSGIEVISRTNQMFLVMIIPVGILASILTHKDKDYRNFLPVLENGLQPVLMGALTLLSLYSTFIILGMLLPFAPREGRIGRASMATMLILVVMFLGPLTGPVAIFGAERSMGLSFPSFQILRDIKVGELQRLDLLGIMLWSMGSFSKIALSLFATCLGVSQWFGLKDFRVLALPVGSLMVIVSLLHSRNFLELYSFFQSTYPYYSTFCGLLLPAFLFGVAVLRRMRVPGAPAGGGERS
>NC_017672.3|WP_013916604.1|3604322_3605771_+|spore-germination-protein
MIALSASLAQNLHEIEEYMGHSADLCVRRFELSPGREAAVLYLASLVDKALIDEFVMQPMLESGKPEEGTAEKVELPVHLQQTVSSVEKAASALLQGCSLVLVDGLSAAKSGLTSGGERRAVSEPSAESVVRGPRESFNESLLTNIGLIRRRLASPHLRTERLMIGSVTNTPVSILYLEGTAKEEYVTEVKERLGSIRLDGILESQYLEEYLEEKQGYTPFPTVFNTERPDRVAAGLLEGRVAVLMEGTPVALVVPATIGLFLYSNEDYYQRYDIATFLRILRTFTFLISIAMPGFYVALLTYHQEMIPTPLLVALTGQREGVPFGIAIEVFLMEMTFEILREAGIRLPKTIGSAVSIVGGLVLGQAAVEAGLVAPGTVIAVSVTAISSFCTPAFNIAISARLIRFVLILLCAALGAFGLFFGLILTVIHLNTLRSLGVPYLSPISPFHGKDWRDLFIRAPLRRMTQHPEELRTREEGGERG
>NC_017672.3|WP_014370087.1|3605770_3606940_+|Ger(x)C-family-spore-germination-protein
MRHAILRSLPLLAGCLLLLTGCWDRKELNNVAIVMGVGIDKGQGEEYKVTAQVIKPSPPNKGGGGGSELPTWSLTAKGTTVLDAINELNRISPRRLYWPHTQLLLLGRELAESGVGGILSWFERDRDSRSGTYIAVTHGKAEDLLNQKIELGNVPSKAIVELIESAIQRQLTSRRTTLRDFISVLSTPGIDAAVDVIDSRAIRGKVETYELRGAAVFKGDRLKGFLPSEEASTIEMASGTFKDAVINIPCPQEGMSGEVSFTVTDFQRKISMTLESGRPVMGLRMIVEGNLSDQSCPVRLLQEDLRSKVEAAIGQRIQQAVKTSFAKTSKWGADIFGVGRELHRTHPSVWRQQGQEWDRNLATAKLQPSVSVSIRRSGLVLEPTPAGMR
>NC_017672.3|WP_014370088.1|3606965_3607178_+|hypothetical-protein
MRHLLPFILFTAVLAVDLRRLKRGGKRGAAVYLALLGGAFLLSELYLFHLEPPSPNRIISQLVRLLIPAA
>NC_017672.3|WP_013916607.1|3607364_3608387_+|ABC-transporter-substrate-binding-protein
MNKRWKQGAAAVLALGLGLAAVLSGCGPAKTEESVKVRIGEVTRSIFYAPQYVAVNQGFFKAEGLDVELTTTFGGDKTMTALLTGGIDVALVGSETSIYVAQQGSGDPVINFAQLTQTDGTFLVSRKPAQGTFDWNSLKGSTFLGQRKGGMPQMAGEFTLKKHGINPQKDLNLIQNVEFANIPTAFASGTGDYVQLFEPQATMFEQQGKGYVIASFGVESGRLPYTVFMTKKSYIDKNPDALQKFTNAVQKAQNWVAASSVDVIADSIASFFPDTDKEIIKGVVKRYKDQGSFASDGIVDAEEWSNLQNVMEAAGELKARVDHGSLVDNRFAEKAKASVK
>NC_017672.3|WP_014370089.1|3608497_3609292_+|ABC-transporter-ATP-binding-protein
MESAVELDHVSHVYVNGRGAYPALLDISLTVRQGEFISLIGPSGCGKTTLLSLISGLLTPTAGNVRVFGEKVEQGGVQRIGYMLQQDYLFPWRTIGANASLGLELLGRLDAASQKLVDGLMEEMGLGGQSQRYPHQLSGGMRQRVALVRTLATEPDVLLLDEPFSALDYQTKLQLEELVSGTLKARGKTAVLVTHDITEAVAMSDRVIVLQPNPGRLLADMEVPELIRAASPLKARETEGFHELFHRLWGLFESMDKGGGRSHG
>NC_017672.3|WP_013916609.1|3609284_3610133_+|ABC-transporter-permease
MAELKGTPAEEGRQQPAELADEVYTAFRRSERRLALSVRLTQLALLVLFFGLWETAAAFKWIDGLLFSSPSRIVQLLYEKLLDGSLLEHTWVTVWETVVGFVLGTLLGTAGAALIWFSPFLSRVLDPYIVVLNSLPKVALGPLFIVALGPGVLSIIATTLSLTVIITILVIYNAFREVDPNLVKVVRIFGGSTGTVFRKVILPASYPAIISTLKVNVGLAWVGVIVGEFLVSKAGLGYLIIYGFQVFNFTLVIGALFVIAAAAALMYQLVASVESRLIGRSR
>NC_017672.3|WP_016362588.1|3610261_3611038_+|hypothetical-protein
MNRTPTYRRYRALLSPFNTSQIHRKNPWISAFFSFSFPGFGNLLQHRYAKGFTLISWEIFINSHAKINTGIMYSLQGHFAKAKETLNPNWLMIYVSIYMFGIWDSYRSTVELNKLYTLADREDAPIKPMAMSVWDINFLNKRVPWVAAAWSLLAPGLGHLYLHKVLPGFFLFGWTIAIMYFSHIPMAMLYTASGDFRQAKEVLDMQWTLYLPSIYCFVFYDAYVSAVEYNKLFEKEQSKHLRTNYQDPGFRMPRSQEG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_6

3770218-3770406

Orphan

Consensus_repeat	Method
AAATAGCGGAACTCAGGTACGCTAT	CRISPRCasFinder

3 spacers

WYL,csa3

The CRISPR arrays of NC_017672_6

>merge|NC_017672|6|3770218-3770406|CRISPRCasFinder
GAATAGCTGAACTGAAGTGTGCTGTCGGGCTGATGTGAAGCGCGATATTCGAAATAGCGGAACTCAGGTACGCTATCGTGCTAATGCGCGAGGTGATAATCCAAATAGCGGAACTCAGGTTCGCTATTCGTGCCGAGCAGGGGGGCTGGCGGTGAATGCCGGGCCAATAAGGCATCTGAGTTCCGCTAT

>NC_017672|6|4|3770218-3770406|CRISPRCasFinder
GAATAGCTGAACTGAAGTGTGCTGT	CGGGCTGATGTGAAGCGCGATATTCG
AAATAGCGGAACTCAGGTACGCTAT	CGTGCTAATGCGCGAGGTGATAATCC
AAATAGCGGAACTCAGGTTCGCTAT	TCGTGCCGAGCAGGGGGGCTGGCGGTGAATGCCGGGC
CAATAAGGCATCTGAGTTCCGCTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014370135.1\|3763387_3768550_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226415
NC_017672.3\|WP_013916711.1\|3776281_3777223_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381308
NC_017672.3\|WP_013916717.1\|3781912_3782707_+\|helix-turn-helix-domain-containing-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|176902
NC_017672.3\|WP_014370136.1\|3768755_3769658_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|187553
NC_017672.3\|WP_013916708.1\|3773352_3774192_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NC_017672.3\|WP_013916705.1\|3769668_3769986_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014370133.1\|3760701_3761136_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377503
NC_017672.3\|WP_014370134.1\|3762406_3763234_+\|esterase-family-protein	unknown	unknown	gnl\|CDD\|223700
NC_017672.3\|WP_013916700.1\|3761459_3761969_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|378975
NC_017672.3\|WP_014650938.1\|3781315_3781717_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NC_017672.3\|WP_014370137.1\|3771090_3773262_-\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NC_017672.3\|WP_013916696.1\|3760179_3760455_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014370142.1\|3779441_3779954_-\|GyrI-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|214874
NC_017672.3\|WP_013916701.1\|3762031_3762373_+\|bacillithiol-system-redox-active-protein-YtxJ	unknown	unknown	gnl\|CDD\|378538
NC_017672.3\|WP_013916709.1\|3774315_3775317_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_017672.3\|WP_014370141.1\|3778479_3779475_+\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NC_017672.3\|WP_013916695.1\|3759310_3760099_+\|TIGR00266-family-protein	unknown	unknown	gnl\|CDD\|376704
NC_017672.3\|WP_014650937.1\|3780163_3781177_-\|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|176237
NC_017672.3\|WP_014650932.1\|3758022_3759201_+\|formate-dependent-phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|236454
NC_017672.3\|WP_016362609.1\|3777422_3777962_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014370135.1\|3763387_3768550_-\|AAA-family-ATPase	gnl\|CDD\|226415	COG3899, COG3899, Predicted ATPase [General function prediction only].	7.46754e-141
NC_017672.3\|WP_013916711.1\|3776281_3777223_+\|aldo/keto-reductase	gnl\|CDD\|381308	cd19082, AKR_AKR10A1_2, AKR10A family of aldo-keto reductase (AKR). Streptomyces bluensis aldo-keto reductase (BlmT) and Streptomyces glaucescens aldo-keto reductase (StrT) are founding members of aldo-keto reductase family 10 member A1 (AKR10A1) and A2 (AKR10A2). BlmT is bluensomycin aldo-keto reductase (AKR) and StrT is streptomycin AKR.	9.65773e-153
NC_017672.3\|WP_014370136.1\|3768755_3769658_+\|TIGR01777-family-protein	gnl\|CDD\|187553	cd05242, SDR_a8, atypical (a) SDRs, subgroup 8. This subgroup contains atypical SDRs of unknown function. Proteins in this subgroup have a glycine-rich NAD(P)-binding motif consensus that resembles that of the extended SDRs, (GXXGXXG or GGXGXXG), but lacks the characteristic active site residues of the SDRs. A Cys often replaces the usual Lys of the YXXXK active site motif, while the upstream Ser is generally present and Arg replaces the usual Asn. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.93668e-121
NC_017672.3\|WP_013916717.1\|3781912_3782707_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|176902	cd08893, SRPBCC_CalC_Aha1-like_GntR-HTH, Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; some contain an N-terminal GntR family winged HTH DNA-binding domain. SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain of a functionally uncharacterized subgroup of CalC- and Aha1-like proteins. This group shows similarity to the SRPBCC domains of Micromonospora echinospora CalC (a protein which confers resistance to enediynes) and human Aha1 (one of several co-chaperones which regulate the dimeric chaperone Hsp90), and belongs to the SRPBCC domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. Some proteins in this subgroup contain an N-terminal winged helix-turn-helix DNA-binding domain found in the GntR family of proteins which include bacterial transcriptional regulators and their putative homologs from eukaryota and archaea.	5.98335e-17
NC_017672.3\|WP_014650932.1\|3758022_3759201_+\|formate-dependent-phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|236454	PRK09288, purT, formate-dependent phosphoribosylglycinamide formyltransferase.	0
NC_017672.3\|WP_014370133.1\|3760701_3761136_+\|hypothetical-protein	gnl\|CDD\|377503	pfam05360, YiaAB, yiaA/B two helix domain. This domain consists of two transmembrane helices and a conserved linking section.	1.39099e-14
NC_017672.3\|WP_014370134.1\|3762406_3763234_+\|esterase-family-protein	gnl\|CDD\|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	1.32816e-38
NC_017672.3\|WP_013916700.1\|3761459_3761969_+\|metallophosphoesterase	gnl\|CDD\|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	1.69343e-37
NC_017672.3\|WP_014650938.1\|3781315_3781717_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.21048e-40
NC_017672.3\|WP_014370137.1\|3771090_3773262_-\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NC_017672.3\|WP_014370142.1\|3779441_3779954_-\|GyrI-like-domain-containing-protein	gnl\|CDD\|214874	smart00871, AraC_E_bind, Bacterial transcription activator, effector binding domain. This domain is found in the probable effector binding domain of a number of different bacterial transcription activators.and is also present in some DNA gyrase inhibitors. The absence of a HTH motif in the DNA gyrase inhibitors is thought to indicate the fact that these do not bind DNA.	3.2027e-22
NC_017672.3\|WP_013916701.1\|3762031_3762373_+\|bacillithiol-system-redox-active-protein-YtxJ	gnl\|CDD\|378538	pfam11009, DUF2847, Protein of unknown function (DUF2847). Some members in this bacterial family of proteins with unknown function are annotated as YtxJ, a putative general stress protein. This cannot be confirmed.	1.59685e-48
NC_017672.3\|WP_013916709.1\|3774315_3775317_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.76656e-81
NC_017672.3\|WP_014370141.1\|3778479_3779475_+\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.24688e-61
NC_017672.3\|WP_013916695.1\|3759310_3760099_+\|TIGR00266-family-protein	gnl\|CDD\|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	4.78703e-85
NC_017672.3\|WP_014650937.1\|3780163_3781177_-\|NAD(P)-dependent-alcohol-dehydrogenase	gnl\|CDD\|176237	cd08276, MDR7, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.34679e-174
NC_017672.3\|WP_013916708.1\|3773352_3774192_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.61285e-25

>NC_017672.3|WP_013916705.1|3769668_3769986_+|hypothetical-protein
MLIYGSTDIHELRFEELTARVERRDEQWIDVEVGFRVAGPDAVPEDITELGALLVVTYRGDIAEIAPQDEGRDCEYQFTESEKAQLREFYEREVRPQVLQAAGQE
>NC_017672.3|WP_014370136.1|3768755_3769658_+|TIGR01777-family-protein
MKVAIAGGTGFIGGHLTRYYAERGTEVVLISRSARASDKERVKYVTWSELEKNVSAVEGAEAVINLAGESINQRWSEAAKARILDSRLDSVRRVADIAGRLERKPVLVNASGMSVYGLSDTESFSEESPHRLDHFLAEVVEKWEAEIRRVPAARTVMLRVGVVLGRDGGAYPKMRLPFVFGAGGRIGSGRQWLSWIHVDDIIRLIDYCVTQEEMAGPVNATAPEPVTNDAFGRALAKVMGRPYLFPVPGLVMKLIFGEMSMLLLEGQKVLPQAALSGGFRFTYPTIEEALRSLERRAKGG
>NC_017672.3|WP_014370135.1|3763387_3768550_-|AAA-family-ATPase
MALQLNEGAAERLDDTAAATWFRTEDSGGRRRLVKALKAEYGTPGEVQRLRLELEKGRRLGFPEVLLPLGIVTFRGTPALVTEAAEGVLLSSVLSPVPAAPEVFLPLALSMTDAVRQLHKHKFAHTALSHQAFFIDKDAAGGRVRLTELHSLVSLGSPHDPAAPAESAVPPQPERNPFLAPEQMHDPAAGRVNVRPDHRTDLYALGVLFYRLLTGLFPSLPDIGSDGSAPSPVPPAELAVSVPEVLSAVVMKLLTRQPDQRYPSAFALHRDLAKCLEQWSAAGTIEAFALGTVAGSDHFAISETIYGRETELEQLHAAYGRCLSGSLQTAFVSGLSGIGKSYLIHEFQKGLTPGSALYVHGKFDQYKRESPYYAIRQIGRQLMQHLLQQPPEELQLLKERIRDAVGPNGQILLEMNPDLEAVIGKQPPLTKLPPAEMHNRFILTIRQYTSVFASQEHPLVLFLDDLQWADPASLQLVSEFLLEMPFPYMLFIGAYREREVTDSHPLRSLIGKLGRSRTAPVEIRLEPLQEPHVARLLEDTLQPSKQDPRELAGLIMSKTKGNPFFTKQFFRSLYDQHLLRFDDRSCCWAWDTDRIKELHITDNVVDFMISKIRRLSESMQHLLMHAACLGQQFTPEVLSLVTGYDGDRTALLLKQAVDDSLLLRVVGGRRTSSAEAVTSYKFMHDRVYQAVYSLLPDSDKKRIHLHIGRLLQAYYAEEEHDLTVFEVTDQLNLGSDGITSPPEREDLAELNLRAARKAKGNSAFDTAYRYASQGVQLLGEEAWSSRFELAYALRLEMAELEYLCGHFGEAKASFETVLRLSRTKLEKADVYNLMIILHTHIGEHEQAVRLGLEGLKLFGLSLRPKIGKGSILWEMFKSRIHLGLRSQDDLLDHYPMSEPEHEAVMRFLVNLIPSAYFLDADLYVYLMLRMFNYSLMHGHSDGSAYAYSTYGVILSAVFGRLKAGWEYGRLSVQLSDIYPNPAIKSKVYFAYGGFSNNIREHIEANVGHLRKAYQYGVESGDLVYAGYSIAFSFFMQVLKGDTLPEILQESEKYRQFVHQAQDRDVIWIYTVIQRYILSLKETAGAPNAPQEPLLSPEEAQIVRGLSNKAVVHTFYGLQAQSFYLLNHLEEARLICEETEANLGQMFGFPHIELHHFQYGMVLASLYDHAGNALQMKYRKRIRKSLKILGKWAAHSPSNYLHMNLLLQAEYDRITDKRMQAAEKFDLAIQAAARSGFLPREALANERAALFYLRTGRIKIAKAYLLDARSLYERWGAARKVAQLEALYPGLLGWASSADVLPAACGVLKATPPVTYQTVFHHMLDCMMSQMLEYARADKALLMLEQDGQLQIEAEKSLKDPFRSLHSTPVEEGVPAAVTAVDYVKQSGEPLLLKEAPDAGLFGNDPYIREIRPQSLLCLPLTGRGEAAGILYLESRTAAHAFQPDRFGRLKLLAAAAAELVRRARLTASLEVKEDLLPQAHELGRQQSRPQPVVPESRRGTARDGTPSSRQLAQTQFIRRLQGVHALLALNKTETAQESIAVWCEELVQMTLADSVAFPALRSALLSLLPAITAAGIELQVDGRLDCLFERLSLPPSLFAGTLQPLLQHALDAAAARESQRVVRLTLTESESHYGLAVLYSGSPVGEEPRHRPFEKAPPLRAEDSPVVPLVQSLQHMLQPYGGELQCRYEAGRGMIFTLRLPKRAAGDRVPREAAASGLDH
>NC_017672.3|WP_014370134.1|3762406_3763234_+|esterase-family-protein
MAVQSFSFFSGALYARKVCQVYLPPSYDASEDTRYPVIYLLHGLNGDETSWLVKGGAEAQLDRLMGDGTLRESIVVMPSDGGYGHGTFYVNWYDGTGRFEDYFLYDLMPSIDREFRTIADRSSRALCGLSMGGYGAFVLALRNPELFGAAASIAGALMSTGLMTEQFLRSEVSRLVGPVHGPFARELDLHVLAARMLREEQRPELHFNCGFSDYLYPLNSAFKALLDQLNYPHDYAEYEGEHNWDYFGGHLAEALAFIERSFAGAPAGEAPAEIG
>NC_017672.3|WP_013916701.1|3762031_3762373_+|bacillithiol-system-redox-active-protein-YtxJ
MSKWKEITTKEEWEQYYEGSGSKPFVVLKHSTACPVSFNALQEYEAYLGKTPNEQVDYILVKVIESRPVSNQIAEETGVKHASPQVLYIKNKETVWNTSHWSITEEHLTAVLN
>NC_017672.3|WP_013916700.1|3761459_3761969_+|metallophosphoesterase
MRIGVVSDTHMFGRGAALPAALVRGLQGTDLILHAGDWMDERVIALFEAIAPVDGVAGNNDGPEIIRRFGRRKVLELAGYRIGLVHGDGGRSTPETAYAAFRTKEGEVLADVVIFGHSHTPFHEVRGGQLLFNPGSPTDKRRQPLYSYGILTLGESVSAELFTYEDKSP
>NC_017672.3|WP_014370133.1|3760701_3761136_+|hypothetical-protein
MRKRNTSAFTFLAWTSFASALLAMFIGITTLEETLSVKGYYAVSALYLTMASFVLQKTVRDNQEDGTQARRRNTGAFTFLSWTAFSTALLAMFIGIVNLEQPLSVQGYYAVTALFLTMSSFVLQKTVRDNKEDSEMYAEPDTHE
>NC_017672.3|WP_013916696.1|3760179_3760455_+|hypothetical-protein
MAYNPQVTDAKVVSYNPKNGLFEIVANLKDRTVCRLTYESDETGGAKATHISRLLQEPCPICRKDFLCNCMDKFKENIAGQALEHTGVPTA
>NC_017672.3|WP_013916695.1|3759310_3760099_+|TIGR00266-family-protein
MNAHEIDYAIHGSEMQYVEIELDPGESVIAEAGSLMMMDQSIHMETIFGDGSDQGKGLMGKLFGAGKRLLTGESLFMTIFTNRGHGKERASFASPYPGRILPMDLSMLGGKIICQKDSFLCAAKGVSVGIDFQRKLGAGFFGGEGFIMQKIEGDGLAFVHAGGAICERELRPGEMIRVDTGCLVAMTQGVDYDIEFVKGVKTALFGGEGLFFATLRGPGRVWIQSLPFSRLADRVLAAAGPGGRKEEGSILGGLGNLLDGDR
>NC_017672.3|WP_014650932.1|3758022_3759201_+|formate-dependent-phosphoribosylglycinamide-formyltransferase
MYGAPLSAGAHKIMLLGSGELGKEVIIEAQRLGVETVAVDRYANAPAMQVAHRSYVISMLDGEALRELIEKEKPDLIVPEIEAIATQTLVELESEGYRVIPTATAARLTMDREGIRRLASETLGLPTARYAFADTLDELKAAVAEIGTPCVIKPIMSSSGKGQSVCRTPDDIETSWNLAMEGGRAKKARVIVEEFIRFDSEITLLTVRSASGTSFCAPIGHIQKDGDYIESWQPHFMSAAQLEEAQEIAAKITDALGGAGLYGVELFLAPDKVYFSEVSPRPHDTGMVTMASQDLSEFALHVRAILGFPVPTIRLLTPAASYTLKADRDAETFRIGGLPEALALPNTQVRVFGKPETKPGRRMAVALSTGETVEEARRLAKEAAGNLRIEYS
>NC_017672.3|WP_014370137.1|3771090_3773262_-|DNA-topoisomerase-III
MKSLVLAEKPSVAKEIARVLGCQQKHKHYMEGPQYVVTWALGHLVTLAEPEEYDLKYKTWNLEDLPLLPSKMKLKVIRETTPQFKAISQLAQRGDLKELIIATDAGREGELVARWIMELVRWRKPYKRLWISSQTDKAIRDGFAQLKPGPAYDPLYRSAVCRAEADWLIGLNITRALTCKHNAQLAAGRVQTPTLAAMMDREAQIRSFQAKDFWMLRAQLGSFQALWRSQAHPDGRLFDKAAADTLLERLKTARSAKVSALKVSEKSEPHPLAYDLTELQRDANKRLGFTAKQTSNVLQRLYEQHKLVTYPRTDSRYLSSDMVSTLPDRLKALLGTPYGASAKGLLARPLPVTKRIVDDSKVSDHHAIIPTDERPQLQLLGADERRLYDLIVRRFLSLFFPAFRYDETAVTLDIAGESFHAKGRIVKDQGWKAVYDGSSAPSEADDDDAPEEEPSSLQSLPALQLGTELKDLRLSQQKGTTKPPGRYTEAGLLSVMEKQGLGTPATRADIIEKLLSTDTIERRMNTLQPTGKGVQLMELVVPELRSSELTASWERELERIAKGQGDPDAFMAGIRKQTEAIVRDVKNSSAEYKPHNLTHSKCPDCGSPLQDIKGKRGRMLVCSSRECNYKRAAEAQLSNKRCPQCRKKMEIHTGKAGKYAQCRPCNVIEMLNDTGGAGGRGKAGKRQQSQLAEQYSDNAKLPSALEEALKAALGKGSGGSDDE
>NC_017672.3|WP_013916708.1|3773352_3774192_-|AraC-family-transcriptional-regulator
MKRQSMLPTLNRTEFMILPESVGWYTEMPDHEVSRKAGVLNNFSIHIVLGGRGCVEHDRSVYTLQRGDAFLYFPLTEQRYYSSQDDPWEVRWVHFYGSGLREYLIERGFSRSPLWKLRQTKPVEDALDALLVEAEARGFLGLTRLSTLTYAVLAEFVSEAAPWSDPRSAEPGSRVLDLLPAMRAEACLPFDLQEWADRAGVSTYYFCRLFKKATSMTPMTFITLSRLQKGKQLLLEQPDLTVKDIAEQTGYPSVSYFNKRFLEQEGMTPTDYRQLYRKE
>NC_017672.3|WP_013916709.1|3774315_3775317_+|Gfo/Idh/MocA-family-oxidoreductase
MSEKKIRWGILGCANIAVRAVIPGTQKSETGVVAAIASRGIGKAQETAEKMGIPTAYGSYEELLADESIDAVYIPLPNHLHKEWTIKAAEAGKHVLCEKPAALNAEETREMAAACEKAGVIFAEAFMYRYHPRYQMIREIIASGEIGEVRGIHGAFTFNNAKDTGNVRYQQHMGGGSIYDVGVYPISAARFILGQEPEAATVHGFFSPEHDGVDMMASGLLEFPNSVALTFDCGMWAAGRNVLEILGTDGRIEVPSAFVTNGSERDHFIVHAKGESREVQVPYLNQYALQADAIGRSVLYGEPMPFGPQDAVNGMRVVDACLTSARERRRIEL
>NC_017672.3|WP_013916711.1|3776281_3777223_+|aldo/keto-reductase
MRTITIQGLDKPVSCLIKGSDYFREDVYEKAARNLDAYFAIGGNTIDTAYIYCGGESEKTIGRWMAERGNRDQVIILTKGAHHNKDGPRVNPEAIEADLQESLQRLGTDYVDLYALHRDDPSVPVGIIMDALNEHIQAGRIRAIGGSNWTTARLQEANEYAAQHGLVPFTFSSPNLSLAKANEPFWSGCVSADSSDCAWHEQHQLPLLSWSSQARGFFTGRFTPEVRDNADLVRVFYSDANWDRLRRAEQLAAERGVTAIQIALAYVLNQPFPACALIGAQTPEELESCRQGAEIVLTREELEWLEHGTPVRA
>NC_017672.3|WP_016362609.1|3777422_3777962_+|hypothetical-protein
MDKHAKKEAVHQRVQKGGACEEAVIMDKPALKFIGLAAEVTLYDVQFNKTTLKLVAHFHSIRCEIKRSMNDGVAYGLSADPENYRPAAPGSRVRGIRYGDLVSCSDEKAAIEGRGGVPLPKKWPESLGMKRVTYTWEAGDIGDADCQPGGYDFCTCDGSGAFHKLVQPSARLGREGRPA
>NC_017672.3|WP_014370141.1|3778479_3779475_+|YafY-family-transcriptional-regulator
MTKSKRLMELMIAVNKRRRFTVRELAEEFGVSTRTIMRDLQVLDELGLPLYAEYGPHGGYRVLNERLLPPIMFSEQEALAMFFAYQSLQHYGALPFSEESVTALKKFYYYLPDDTKQKIDRLQERVVFWTPKRQAAVPHLKLLLDASLQGRPLRITYDSREGPGERAIQPIGVYSYNGYWYCPAYCFRKQRYLLFRVDRVLQAEPAGEEHPAVDLSEYTITDWFLPPPQQPPGPGGDAHGLLQLEVRLTKDGVRRCRWESWFQEELVVGEEGEGLLRIRIRHDEMDYYTGYFLSLGADAVVVQPPELVSRLREAVRKLYDAYGAGETAGPP
>NC_017672.3|WP_014370142.1|3779441_3779954_-|GyrI-like-domain-containing-protein
MKPRIEKHGEFAAVGTKGQHRLTEGVIPTIAGQWDAFMRRAAEIPGRGPATLGICWGIEAASGEPFDYLTGALVEEMPPELPSGMTAVTLEPRLYAVFTHRGPVARLDATYASIQAWLESNGTYRRADAPDFEYYDHRYASAEPESSEFDIYIPVTEPACYGGPAVSPAP
>NC_017672.3|WP_014650937.1|3780163_3781177_-|NAD(P)-dependent-alcohol-dehydrogenase
MRAFDIQGGFGLERITLAERPKPAPGPGEVLLRIRAASLNARDLGVVGGFYVGAETLPLIPVSDGVGIVEELGEGVTRVKPGDRVCPIFVQDWLAGTPTEAMLGSTLGGPRDGVLAEYGVFPQGSLVHVPEHLTDEEAASLPIAALTAWQAVVTEGRVRAGDTVVVQGTGGVALSALQFAKLHGARVIVTSSSDVKLERAAALGADLGINYVKSPQWDQEVLRLTDGRGADHIVDLGGAATLNASLAAVRPGGRVSIVGVLSGVTAAGLDLIPAIRKKVTLQGINVGSHGMFEDMNRALALSGVRPVIDRVFPFTEAVQALRYMQEGVHFGKICIRL
>NC_017672.3|WP_014650938.1|3781315_3781717_+|helix-turn-helix-transcriptional-regulator
MRTDGRPEKDISVTVCSYSLALDVIANKWKPLVIYALENGSQRYGDMKRRIEGVSQKMLTETLRGMERDGLVVRKVHPAVPPAVEYTLTPLGRTLIEPLQALHVWAKAHHEDVLSARERYDGQDGQDGQTGGA
>NC_017672.3|WP_013916717.1|3781912_3782707_+|helix-turn-helix-domain-containing-protein
MTTVQSKDSAIFLVLADPRCRELLQRLAASPGLSVSGLSDELELPRAAVLKHLKMLEEAELAASRRIGREKLYSADRERLRGLMERLLGRPEDTRGGRLGELKRMLSEEKQRSVRMLPRQTYGTLIRSSPARIWEEVLSPEQPAGFWRGCRLILGGGELSPYRLERPDGREEARGMVTAAEAQRRLELTWGSPDESEAGTAEGRLALELERLPGRPEVCRVILVLTAEIRTEDSIRAADGGWPGRLAGLKSYVETGEGMWEEKP

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_7

5712182-5712275

Orphan

Consensus_repeat	Method
GGTCACTGTCAAAACCATATATCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_7

>merge|NC_017672|7|5712182-5712275|CRISPRCasFinder
GGTCACTGTCAAAACCATATATCCTCGCTGGGTATAGAAGACCCCATTTCCGCTTGGCTTCGCACAACCGGTCACTGCCAAAACCATATATCCT

>NC_017672|7|5|5712182-5712275|CRISPRCasFinder
GGTCACTGTCAAAACCATATATCCT	CGCTGGGTATAGAAGACCCCATTTCCGCTTGGCTTCGCACAACC
GGTCACTGCCAAAACCATATATCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014371085.1\|5723422_5724295_-\|DUF4362-domain-containing-protein	unknown	unknown	gnl\|CDD\|372994
NC_017672.3\|WP_016362783.1\|5702823_5704212_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240539
NC_017672.3\|WP_016362786.1\|5709330_5710974_+\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635
NC_017672.3\|WP_014371079.1\|5717970_5718147_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014651827.1\|5712408_5714709_-\|ATP-dependent-helicase	unknown	unknown	gnl\|CDD\|223288
NC_017672.3\|WP_014651828.1\|5714855_5716310_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|236823
NC_017672.3\|WP_014651826.1\|5711129_5711504_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014371072.1\|5708183_5708402_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014651824.1\|5708483_5709161_-\|SOS-response-associated-peptidase	unknown	unknown	gnl\|CDD\|376837
NC_017672.3\|WP_013918883.1\|5711743_5712043_-\|DUF2325-domain-containing-protein	unknown	unknown	gnl\|CDD\|378383
NC_017672.3\|WP_014371083.1\|5721164_5721863_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013918874.1\|5702414_5702603_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014371081.1\|5719438_5719744_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014371080.1\|5718218_5719313_-\|DUF4163-domain-containing-protein	unknown	unknown	gnl\|CDD\|377924
NC_017672.3\|WP_016362784.1\|5704476_5705310_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_041618457.1\|5719852_5721028_+\|DUF4850-domain-containing-protein	unknown	unknown	gnl\|CDD\|292760
NC_017672.3\|WP_014371078.1\|5716456_5717872_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NC_017672.3\|WP_014371084.1\|5721941_5723399_-\|DUF5050-domain-containing-protein	unknown	unknown	gnl\|CDD\|379846
NC_017672.3\|WP_014651821.1\|5705403_5706255_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_017672.3\|WP_016362785.1\|5706356_5708084_-\|alpha-keto-acid-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|226470

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_016362783.1\|5702823_5704212_-\|MATE-family-efflux-transporter	gnl\|CDD\|240539	cd13134, MATE_like_8, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	2.82775e-177
NC_017672.3\|WP_016362786.1\|5709330_5710974_+\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.09908e-53
NC_017672.3\|WP_016362785.1\|5706356_5708084_-\|alpha-keto-acid-decarboxylase-family-protein	gnl\|CDD\|226470	COG3961, COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only].	0
NC_017672.3\|WP_014651828.1\|5714855_5716310_-\|amino-acid-permease	gnl\|CDD\|236823	PRK11021, PRK11021, putative transporter; Provisional.	2.15177e-56
NC_017672.3\|WP_014371078.1\|5716456_5717872_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.0201e-122
NC_017672.3\|WP_041618457.1\|5719852_5721028_+\|DUF4850-domain-containing-protein	gnl\|CDD\|292760	pfam16142, DUF4850, Domain of unknown function (DUF4850). This family consists of several uncharacterized proteins around 250 residues in length and is mainly found in various Acinetobacter species. The function of this family is unknown.	5.02501e-82
NC_017672.3\|WP_014651821.1\|5705403_5706255_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.6268e-24
NC_017672.3\|WP_014371080.1\|5718218_5719313_-\|DUF4163-domain-containing-protein	gnl\|CDD\|377924	pfam07833, Cu_amine_oxidN1, Copper amine oxidase N-terminal domain. Copper amine oxidases catalyze the oxidative deamination of primary amines to the corresponding aldehydes, while reducing molecular oxygen to hydrogen peroxide. These enzymes are dimers of identical subunits, each comprising four domains. The N-terminal domain, which is absent in some amine oxidases, consists of a five-stranded antiparallel beta sheet twisted around an alpha helix. The D1 domains from the two subunits comprise the 'stalk' of the mushroom-shaped dimer, and interact with each other but do not pack tightly against each other.	2.04364e-18
NC_017672.3\|WP_014371085.1\|5723422_5724295_-\|DUF4362-domain-containing-protein	gnl\|CDD\|372994	pfam14275, DUF4362, Domain of unknown function (DUF4362). This family of proteins is found in bacteria. Proteins in this family are typically between 93 and 146 amino acids in length. There is a conserved IRIV sequence motif.	5.06658e-14
NC_017672.3\|WP_013918883.1\|5711743_5712043_-\|DUF2325-domain-containing-protein	gnl\|CDD\|378383	pfam10087, DUF2325, Uncharacterized protein conserved in bacteria (DUF2325). Members of this family of hypothetical bacterial proteins have no known function.	2.04691e-16
NC_017672.3\|WP_014371084.1\|5721941_5723399_-\|DUF5050-domain-containing-protein	gnl\|CDD\|379846	pfam16472, DUF5050, Domain of unknown function (DUF5050).	1.97235e-33
NC_017672.3\|WP_014651824.1\|5708483_5709161_-\|SOS-response-associated-peptidase	gnl\|CDD\|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	1.97304e-110
NC_017672.3\|WP_014651827.1\|5712408_5714709_-\|ATP-dependent-helicase	gnl\|CDD\|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	2.17048e-114

>NC_017672.3|WP_013918883.1|5711743_5712043_-|DUF2325-domain-containing-protein
MTMKRVAIIGGSQTGTFKKLGEKRGLLVEHHNGKTGGGPVDEYFQRIINKADVIIVLRGAIKHTSMWAVRELAEKKGKKIDYHDGFGASGALEKALQLV
>NC_017672.3|WP_014651826.1|5711129_5711504_-|hypothetical-protein
MIKTVWLGLLLALNPAADQTAPQPVDVADYYGTNPTLGDTSFAKTVSPHAGVPQFRVQGANPQQQADPTDGRWGDPGDVPVYRPAVAPANENQGSHWLGLAGLLGLLGLRRGRAKRPASPTEEG
>NC_017672.3|WP_016362786.1|5709330_5710974_+|diguanylate-cyclase
MIKLRTLLILTITGIVILLTSLLGVLFTRHSTNEIKKEIGHSLAGTAYQMSDKLDNFMWSRAGEMEILTTLDIFKQGGDIPGVQAALDQLQTSFPSFSWVGFMNTEGQVLAATDGILVGTNIASRPVFKEGIKGRFIGDVHEAVLLAKLLPNPTGEPLQFVDISLPVKDHRGRTIGVLAAHMSWEWSREVQRTILEPQLHRSENLELFIVSRTDHTVLLGPEDMVGKPLEIDSVNRAQAGGSGWELAAWPDGRSYLTGYAYGDGYLSYEGLGWTVLVRQPESAAFARVAGLRSDFALAGTLAAMLFAVIGWFLAARITRPINSLTEAADRLRTGEAAELPENRGFREMYILSRSLRSLVESLARTENELGDMKNLAHFDPLTGLPNRVALESYLETTLEEVEPRTETLAFLYLDLDGFKKVNDTLGHHTGDILLQKVAKRLISLQQAGNITVRLGGDEFLHILRFPKESAFEETKRAAEEIIALLNKPFLVDYNRISIGCSIGAAFYPDQDENAGQILKIADECLYRSKRAGKNCVSFSDELTMKLQ
>NC_017672.3|WP_014651824.1|5708483_5709161_-|SOS-response-associated-peptidase
MCGRFTLTVSPEAILEQFDLPGGLEEYHPRYNVAPGQQVWAIVHDGEAKRIRQLHWGLVPFWAKDPKIGYRTFNARSETAAKKAAFREPMKHSRCLIVADGFLEWRVRSGKAKQPVRFRLKSREVYGFAGLWETWRGKDGTEMGTCTILTTQPNEIVREVHDRMPVILPREAERLWLDPGVEDPGHLQGLLQPYPAEEMYAYEVSPLIGNVRNDSAELLEELNSK
>NC_017672.3|WP_014371072.1|5708183_5708402_-|hypothetical-protein
MRPLVNDIELCTALVYQTEILVFAGREWVHRGKILAFTEHSVQIGERRFDRAGCSFWMPQETEEEEVIAVCG
>NC_017672.3|WP_016362785.1|5706356_5708084_-|alpha-keto-acid-decarboxylase-family-protein
MSAKTDKDRSSAGRAEEAAVSLGRFLFDRLKREGVTEIFGVPGDYNFTLLDELERCEGMRFIGGRNELNAGYAADSYARLRGLGALITTFGVGEMSAANAVAGAYSESVPLVHIVGTPKSAAQRERRLMHHSLLDGDYEVFRRAYGEITAYTAVLTPENAAAEIPKAIRTAKEKKKPVYLAVAIDLVDRPVVVQAHGEPEPKLQRRTDPAVLEAASAHAKRLLGAAGRAVILSDLPVQRFGLGEPVQRLAEALNVPAASTMLGKGSFDEGHPNYIGVYGGEFGSEDVRSIVEEAGCLIAVGLVRSDGNLANFTAKLDTAQLIEIQPDSVRIGEALYPGIRAEEMLRALEESGFRGGELPRVRHPYDEPAGGPGDAVTAKTYLPRFQRMLKEGDVVVVETGTLAYGMSEVRLPKGAAYIHQGAWQSIGYALPAAFGAAVADPQRRIVLFTGDGALQLTVQEISSMLACGGRLILFVLNNRGYTIEKYLNVRTERQPYNDIPEWSYTRLAEAFGGEAYTARVRTNGELDAAMAEAEAQCGRRLCLIELVPEDPMDAPPFLKRKRSYLEAQEALRAKG
>NC_017672.3|WP_014651821.1|5705403_5706255_-|alpha/beta-hydrolase
MSSSGIIDMDGFPLAYRIEGEGPPVLIVGSETYYPRLFSQELRKKLQLIFVDHRAFVKPSRSIKPEDYTLERIVQDMEVIRTTLKLGRVTVLGHSGSAFIALEYARTYPGHTATAVLLNSAPTNSAERQQGSLRHFDETASPERKAKFERDIALLPGDIEREPERRFAHACIRMAAHSFYDPGVDAAPMWAGVYTNMEIIDHLWGRVFAEIDMLERLHEVKVPVWIGLGRYDYLVSPVSLWDGIEERCSHVKVTVFEHSGHNPMWEEPEVFDRMLTEWVDGKE
>NC_017672.3|WP_016362784.1|5704476_5705310_-|hypothetical-protein
MQAVFHERAVRVEEAEIRAVASRLTAIGEQEGNPHGVQVRRFGRVHAFLVKGIPDLYFNSVRGLGLEEGSEERIDEILDFYAEHGASCRFDIVPFGAQPELLRKLAERGYGQYGFHTALYGVVPELGLPTDPRDGQVIVRPLREDEFDLYAEIYSASFGMPAFLQPAVAANNRVLHGRAGWRFYLALYGDEPAAIGALRMEDGIGSLAAAATLPAFRRLGCQSALLLERLEEAARSACGLLVGQAAFGSASQANMERIGMKVAYTKSLWRKIDTGRG
>NC_017672.3|WP_016362783.1|5702823_5704212_-|MATE-family-efflux-transporter
MNTESLPTWKKLSLFAVTWPIFVDSVLRMMLGTADVYMLSRISDGVTGAVGLANEIIVFCILMFGFVGIGTSVAVAQFLGAGRAREASRISALAITVNFIFGLIVSLTLVVFGEGIMRLMNLPPEQTAIAKQYLTIIGSFIWIEALSYAISSIIRSNGQTRDVMFVTLGVNLIHVAGNYLLIFGHFGFPELGVTGAAVSTAASRLIGLVVLIVILYRRIPYPIRLKDYITWNSTYLKQILSIGLPSAGEHLSWQSQHMMIVSFINIIGTAALSTHVYVMNVSNYFMALGMAIGMGTEIIIGHMIGAGETKAAYHKLLRSLRFCFLLTAAVVGFASLFREQLMGLFTTNADIIAMGSGILLLSVILEPGRTFNLVVINSLRAAGDARFPVMMGVLSMWGVAVPLAYLLGIKLGMGLLGVWIAFTADEWLRGLIMLLRWRSRAWESKALVQPAGTAPAAAEQGA
>NC_017672.3|WP_013918874.1|5702414_5702603_-|hypothetical-protein
MRIQVELSVAGQPVKTEELVIEETKLGELTDEEIEQAIEIKIRSWADRMISIAWEVVDEEGE
>NC_017672.3|WP_014651827.1|5712408_5714709_-|ATP-dependent-helicase
MHQRKDFFASKKEELGVSLNEVQKQAIRETEGPLLLLASPGSGKTTTIIMRIGYLIERMGVEPSRIKAVTFSRASAADMKERFARFFPGLEPVKFSTIHSLAFQVLREHFYKTRTPYHLIEGQVELEEETEGDGAQPADHPPLHKKFILRHLFKTIAGENITDEQMEELTTYISLVKNKMIPPERWDSVKTDVPQAHRVLIAYEEYKRAGSGKGLLVDFDDMLTIGNEILERDRELLRRYQRRYDYVLTDESQDTSLVQHAIIEKLVREHGNLCVVADDDQSIYSWRGADPSYLLNFKDAYPAALTLFMEQNYRSSRDIVDVANRFIKRNKNRYEKNMFTRNPRSAPAQIRSFADYKSQAKYLVEEIRGIAELGEVAVLYRNNSSSIALINEFDRAGIPFFMKDTDNRFFSHWVVEDVLNFMRMSFTDKRADLLETIHTKCAGYITKGQMTQLLGIGNQESVFDNLLKHVPLKEYQVKQIELLRDNFRRMHGMAPKDAIRHIRGKLGYEKALDRLCERLGFRKEHLLGILNTLEEIADTLATMEEFAARLKHLEGVLKSSKHKKGQNVVTFSTLHSAKGLEFERVYMIDLIDGIIPSSDDKQGATAEEAALSMEEAVRLFYVGMTRAKRHLELLTYKMRDGEKVQESPFVTDVRQLLNPGKPAVRPEPGRPAAAVTSGRGPSAAQAGAGRAAGSGKSASPARKKNPNAVRQAADLAAGRDVLHPVFGSGTIVKLAGERIHIRFGTTDKVLSVATCLEMGLLELEKS
>NC_017672.3|WP_014651828.1|5714855_5716310_-|amino-acid-permease
MNHARKRGSGAAAQITPQAKQAGAEAFRTEAFPGPGKPIAPDNGSNQGTHAAPGADGRPGEPVVDGRSGMRPSLGLPQIVALYLGSVIGSGILLIPGLAAEQAGPASILAWLAMSILVVPMAVTMGWLAARHPGPGGVSHFVRLAYGAPYGNLTGWFFLLSVPLGGPVLAVTGARYLAVLLHWDAEQVYLTAAVIVLLPLLLNVYGLRLAGRLQTVVVAVILGVLVLSVTAAVPHVDTARLTPFMPHGPLSVVQAAGLMFWCFIGWEAVTHLSGEFVDPRRNAVRGILWSAGIVALVYLAVAFTTVATGSYGGENSAASLSLMVQRSLGAAGGWAVAVAALFICLAAHNAYSSAASRTAYALAQEGAAPKWLGALHPRYGTPVGGLLFIAAGSMAALLLLYSEAVSLAELIALPNAAFIATYIGGCMAGVRLLRDGRWGRRCAGLSLAAVLALYPFLGWPALFPAGAAAILFLRQVRRRNANQV
>NC_017672.3|WP_014371078.1|5716456_5717872_+|PLP-dependent-aminotransferase-family-protein
MFDLSLTNQEELPLYRQLYEQLREGIRDGRIADGSRLPSLRSLRAQLNISKVTVETAYGMLVAEGYAVSRPRSGLYAVRPKGIPPRSSAADPAAPAVAPAPPAAALQEHRIDFRPSAVDPHSFPLRIWRRMLHQASETAAGQLGRYGDPQGEEGLRRVLADYLRTSRGVVCLPEQIVIGSGIGYSMGILARLFTAKSPIAVEAPGYAPVREQWRHCGYEVIPLPAGRQGWALDELGNTGAQAAYLTPSHHFPTGMVMPYAAREQLLSWAHSRDAYIIEDDYDGEFRYEGRPLPSLQSLDRDGRVIYIGTFSKVFSPALRMNYMVLPIRLASLLRSRPDLLHAPSRMEQWAMHAFIAEGHWYRHIRRMRRAYRRKHETLVRGIRSRWDGRIEITGHSAGLHLEITVHTPHPAGRLTALAAEQGADVYDLRESWLEPAPDGPPRLYLGFGGLTEAEIDQGLTRLERAWKSLWA
>NC_017672.3|WP_014371079.1|5717970_5718147_-|hypothetical-protein
MAAGSKNELVRKDAGASEDMRAFLQSTASSGGRGDQKPDHNRKPDEQNKLTDQHNLRK
>NC_017672.3|WP_014371080.1|5718218_5719313_-|DUF4163-domain-containing-protein
MTNIHAHRKIRKTAVSLALAAVLAAGGSLNPAGASAETHEAAARYAITPQPVTVDGSSAVIPVIYSEGSTYIGLRALTEHLGLAIDWDAGERAASVTGRGRTLKVYPDTGVYTLNVNRLYGELPILQDGSLYVPLRFLLERLGYGVSYDQASRTIEVETIQENPLQIVTVTTDGGHPLVDAQYPQIEGFADTAVMGKINETLKKENEARIAEGIRQLGEAEKWNSELKTDNPEIETPQSVYSASYVVTYNENGRLSLYSDYYFYGGGAHGSTVRQGYTFDLKTGELLTLQEAAGSKDYVGIINREVQKQIGDTGLYLIAPFESVEPDRDYFLTHEGLVIYFQQYEYTAYAEGMPEFIIPYASFK
>NC_017672.3|WP_014371081.1|5719438_5719744_-|hypothetical-protein
MMGILFEVVGVLQENKVGFLFKQHTPMIDNQVFSILRLPTGNVKTIHKSMLGHPVRNMKLESGRIQICHGYCQEAQIGTMQERIERILMPKPQAEPAGQAN
>NC_017672.3|WP_041618457.1|5719852_5721028_+|DUF4850-domain-containing-protein
MRFTAARLVTLCGPLSSSKHLESRSDHMPTSRLPSRPFRTAWALVCACTLLLASCEPGGGPSADPKAANPSAAASVEPARTPQAGQPAEAPVQLSTGGGSADAPPPSASPAAAPPSPASSQDNAPSPADANGQPSAASGSAAHNPAAASAPPVPEPPPPAAAGQRPPGKQPRTEKSGRAAFEPAGAAKFEVPVVCVQADYGADPEGITLCPPAPLSFKKYKLTAHEASRMAVYWMSTGYGRGISVLAPGSWAVHDAVMGANGSVSFMLQHPNDPEQRIVYSDSGACQGCVIANIGGFFPGMEAWAEQQGFPVEPVRDFARRIPIGLDLLSYSLKISKTGYEAHGVASKEQPFYQFRLLEVNVKNGSRPLATAALNFFADTERQRIPQPMSP
>NC_017672.3|WP_014371083.1|5721164_5721863_+|hypothetical-protein
MLLDAIKDKVRQESYEDLKLPLDELERLTAFRPLVIQTPKEPAYVLFQAHPESYTAPVQKDGVRKVVDCSLLRPAGKLETDLMLEMYRHRIYTLYAFAFMFTYEDKGLILLWSQQLEQPPTFNRTQTNALLEEALGPEGDSSYFTLSRIFHPAQLIELTYENQTISTAVGGHSFVMIIPVEKKWTLSLRRSKKVPDDDFDILRRKLALYKEEAILLQNYFQRNGLWSEKASL
>NC_017672.3|WP_014371084.1|5721941_5723399_-|DUF5050-domain-containing-protein
MLRKLNLWTAAAAAGLLMLGPITNAEAAATEAVEVAFPAFPVTVNETALDGVHSLYPLLLHKGVTYFPMTWNYTSALGLSVSWNAEDGLSLTKTEGICGPVPQTLSAELKNSGRAADAVPVPFPVTVNGKAVDSPNETYPLLLYRNITYFPMTWRFTKEEFGWQAAWDPVSGYSIQSCPVEAAAGKRLQTALNLSNGGQLAADEKWIYKNPVRNSEGPHSLVRTELNGEHPLKLSDDLAMYINASGEWLYYIAYDQSGTIVKIRKDGTNRTILPATGVGELWADGEWLYYTKRTQQPESRENASSSPPGIYRMKTDGTGGVQLNPSGEVKSLYVYSDRIFYLKGEQGKEGLYSMKLDGSDDRKVQERVTDFIITEDWIYYVRDGKDIRKISLDGSIDIPLLEQEKPYMGRLSYKDGWIYFAAGATGIHGSLPLERVRLDGTGRETVFEARPTAIYWAGEAMYFAQWSLGSHVLYEHQLKEPAPKP
>NC_017672.3|WP_014371085.1|5723422_5724295_-|DUF4362-domain-containing-protein
MNRLVACFAGAAILLWGCESSEMPGKTKNVSAEVTNQHGNVENLTALDQYVQHSLEGQRGAVRIVHMTIEGDPIYNDLSFSGAGHKLRIDTTQDKFGSPKITDLTCRSMEKVESSVSMKYVLRGCSGEADERTVLHIAFDLAKQDRFEFALRYGPSAFDLQNEISTIDSRLSRDLINGSVHVAQGFEIPFEAKQRIYRALVLANYLGTKELSEGCEAAADETSAGSSSEQRNFSLKVLINGGSREFRWANCGNDSSGNTLGLTTVAEEIIREAEQTEAFRSLPPVQGARL

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_8

6492535-6492614

Orphan

Consensus_repeat	Method
CAGCAGTGAAAGCGCAAATACCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_8

>merge|NC_017672|8|6492535-6492614|CRISPRCasFinder
CAGCAGTGAAACCGCAAATACCGCCACCGCTGCCAGACTCCCTATCATGTCCGATGCAGCACTGATAGCGCAAAGACAAT

>NC_017672|8|6|6492535-6492614|CRISPRCasFinder
CAGCAGTGAAACCGCAAATACCGC	CACCGCTGCCAGACTCCCTATCATGTCCGATG
CAGCACTGATAGCGCAAAGACAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_013917599.1\|6486019_6486619_+\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
NC_017672.3\|WP_014652217.1\|6485106_6485691_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NC_017672.3\|WP_014652222.1\|6498084_6498789_-\|5'-methylthioadenosine/adenosylhomocysteine-nucleosidase	unknown	unknown	gnl\|CDD\|350159
NC_017672.3\|WP_013917610.1\|6500954_6501368_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227939
NC_017672.3\|WP_014371492.1\|6494606_6495239_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_017672.3\|WP_013917609.1\|6500348_6500768_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013917593.1\|6481093_6481486_-\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|377129
NC_017672.3\|WP_016362873.1\|6498912_6499935_-\|catabolite-control-protein-A	unknown	unknown	gnl\|CDD\|130546
NC_017672.3\|WP_014371489.1\|6482785_6483073_-\|YlaN-family-protein	unknown	unknown	gnl\|CDD\|377829
NC_017672.3\|WP_013917594.1\|6481689_6482745_+\|calcium/proton-exchanger	unknown	unknown	gnl\|CDD\|273043
NC_017672.3\|WP_014652226.1\|6501944_6503840_-\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|224006
NC_017672.3\|WP_013917601.1\|6488623_6491797_+\|carboxypeptidase	unknown	unknown	gnl\|CDD\|223815
NC_017672.3\|WP_013917606.1\|6496658_6498041_-\|glycine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235240
NC_017672.3\|WP_013917597.1\|6483915_6485034_-\|aminopeptidase	unknown	unknown	gnl\|CDD\|225191
NC_017672.3\|WP_014652221.1\|6495238_6496435_+\|acetoin-utilization-protein-AcuC	unknown	unknown	gnl\|CDD\|212520
NC_017672.3\|WP_016362870.1\|6479850_6481038_+\|putative-lipid-II-flippase-FtsW	unknown	unknown	gnl\|CDD\|274232
NC_017672.3\|WP_014652220.1\|6492739_6494464_-\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|235279
NC_017672.3\|WP_014652218.1\|6486801_6488061_-\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NC_017672.3\|WP_013917596.1\|6483548_6483797_-\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|376329
NC_017672.3\|WP_013917611.1\|6501364_6501898_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|153228

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_013917599.1\|6486019_6486619_+\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	1.65361e-118
NC_017672.3\|WP_014652217.1\|6485106_6485691_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	7.70908e-28
NC_017672.3\|WP_014652222.1\|6498084_6498789_-\|5'-methylthioadenosine/adenosylhomocysteine-nucleosidase	gnl\|CDD\|350159	cd09008, MTAN, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs): bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	7.73808e-103
NC_017672.3\|WP_013917610.1\|6500954_6501368_-\|hypothetical-protein	gnl\|CDD\|227939	COG5652, COG5652, Predicted integral membrane protein [Function unknown].	1.9327e-10
NC_017672.3\|WP_014371492.1\|6494606_6495239_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.49571e-07
NC_017672.3\|WP_013917593.1\|6481093_6481486_-\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	1.76503e-36
NC_017672.3\|WP_016362873.1\|6498912_6499935_-\|catabolite-control-protein-A	gnl\|CDD\|130546	TIGR01481, catabolite_control_protein_A, catabolite control protein A. Catabolite control protein A is a LacI family global transcriptional regulator found in Gram-positive bacteria. CcpA is involved in repressing carbohydrate utilization genes [ex: alpha-amylase (amyE), acetyl-coenzyme A synthase (acsA)] and in activating genes involved in transporting excess carbon from the cell [ex: acetate kinase (ackA), alpha-acetolactate synthase (alsS)]. Additionally, disruption of CcpA in Bacillus megaterium, Staphylococcus xylosus, Lactobacillus casei and Lactocacillus pentosus also decreases growth rate, which suggests CcpA is involved in the regulation of other metabolic pathways. [Regulatory functions, DNA interactions].	1.02404e-157
NC_017672.3\|WP_014371489.1\|6482785_6483073_-\|YlaN-family-protein	gnl\|CDD\|377829	pfam07408, DUF1507, Protein of unknown function (DUF1507). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	1.61647e-40
NC_017672.3\|WP_013917594.1\|6481689_6482745_+\|calcium/proton-exchanger	gnl\|CDD\|273043	TIGR00378, cax, calcium/proton exchanger (cax). [Transport and binding proteins, Cations and iron carrying compounds].	4.55044e-97
NC_017672.3\|WP_014652226.1\|6501944_6503840_-\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NC_017672.3\|WP_013917601.1\|6488623_6491797_+\|carboxypeptidase	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	3.18442e-160
NC_017672.3\|WP_013917606.1\|6496658_6498041_-\|glycine--tRNA-ligase	gnl\|CDD\|235240	PRK04173, PRK04173, glycyl-tRNA synthetase; Provisional.	0
NC_017672.3\|WP_013917597.1\|6483915_6485034_-\|aminopeptidase	gnl\|CDD\|225191	COG2309, AmpS, Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism].	1.75847e-105
NC_017672.3\|WP_014652221.1\|6495238_6496435_+\|acetoin-utilization-protein-AcuC	gnl\|CDD\|212520	cd09994, HDAC_AcuC_like, Class I histone deacetylase AcuC (Acetoin utilization protein)-like enzymes. AcuC (Acetoin utilization protein) is a class I deacetylase found only in bacteria and is involved in post-translational control of the acetyl-coenzyme A synthetase (AcsA). Deacetylase AcuC works in coordination with deacetylase SrtN (class III), possibly to maintain AcsA in active (deacetylated) form and let the cell grow under low concentration of acetate. B. subtilis AcuC is a member of operon acuABC; this operon is repressed by the presence of glucose and does not show induction by acetoin; acetoin is a bacterial fermentation product that can be converted to acetate via the butanediol cycle in absence of other carbon sources. Inactivation of AcuC leads to slower growth and lower cell yield under low-acetate conditions in Bacillus subtilis. In general, Class I histone deacetylases (HDACs) are Zn-dependent enzymes that catalyze hydrolysis of N(6)-acetyl-lysine residues in histone amino termini to yield a deacetylated histone (EC 3.5.1.98). Enzymes belonging to this group participate in regulation of a number of processes through protein (mostly different histones) modification (deacetylation). Class I histone deacetylases in general act via the formation of large multiprotein complexes. Members of this class are involved in cell cycle regulation, DNA damage response, embryonic development, cytokine signaling important for immune response and in posttranslational control of the acetyl coenzyme A synthetase.	7.75119e-167
NC_017672.3\|WP_016362870.1\|6479850_6481038_+\|putative-lipid-II-flippase-FtsW	gnl\|CDD\|274232	TIGR02614, Putative_lipid_II_flippase_FtsW, cell division protein FtsW. This family consists of FtsW, an integral membrane protein with ten transmembrane segments. In general, it is one of two paralogs involved in peptidoglycan biosynthesis, the other being RodA, and is essential for cell division. All members of the seed alignment for this model are encoded in operons for the biosynthesis of UDP-N-acetylmuramoyl-pentapeptide, a precursor of murein (peptidoglycan). The FtsW designation is not used in endospore-forming bacterial (e.g. Bacillus subtilis), where the member of this family is designated SpoVE and three or more RodA/FtsW/SpoVE family paralogs are present. SpoVE acts in spore cortex formation and is dispensible for growth. Biological rolls for FtsW in cell division include recruitment of penicillin-binding protein 3 to the division site. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan, Cellular processes, Cell division].	1.02616e-117
NC_017672.3\|WP_014652220.1\|6492739_6494464_-\|acetate--CoA-ligase	gnl\|CDD\|235279	PRK04319, PRK04319, acetyl-CoA synthetase; Provisional.	0
NC_017672.3\|WP_014652218.1\|6486801_6488061_-\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NC_017672.3\|WP_013917596.1\|6483548_6483797_-\|HPr-family-phosphocarrier-protein	gnl\|CDD\|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	1.12673e-08
NC_017672.3\|WP_013917611.1\|6501364_6501898_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|153228	cd03134, GATase1_PfpI_like, A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus. This group includes proteins similar to PfpI from P. furiosus. and PH1704 from Pyrococcus horikoshii. These enzymes are ATP-independent intracellular proteases and may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow. For PH1704, it is believed that this Cys together with a different His in one monomer and Glu (from an adjacent monomer) forms a different catalytic triad from the typical GATase1domain. PfpI is homooligomeric. Protease activity is only found for oligomeric forms of PH1704.	6.13604e-83

>NC_017672.3|WP_013917601.1|6488623_6491797_+|carboxypeptidase
MELDQEKVTEKQTKEAKKPRSYKRAFFTAGKVTLSGIKWLFILGLVACFLGGGAAFGYVTSLVKDDPVRSKESMLKEMQDDALTGFVYFRDDSVVGQLRTEEDRRMVALNDIPQHVLDAVFAIEDKNFYEHNGVDLKGTARAVVQKLLKEDVQTGGSTITQQLARRVFLTLSRDDSRKAKEILLAMRMERLMSKDEILLAYLNKIPYGNGSSGYNVYGIKAAAKGIFNIDDLSKLNLAQAAYLAGLPQQPSNYSAFTSKGEVDGAAFKRAVQRQQLVLRRMLEEGKITDAQYQEALQFDLKSTLAEKVKRAYTEYPYLMIEVEREAAKALLKAENPKLDPKESPEEYAEALKSMQTKLSRGGYHVYTTIDKDIYSSMRAIAADEKNFTPEDKVKGMEQIGAVLMDSKTSAILGMIEGRDFWKEQLNHATQAYRQPGSTMKPIAAYIPAMEAGTIQPASVIDDVPIILKDGSRGYHIPENWDDGYHGLITVRRAFNQSYNIPAIKLFLNDVGIEKAWTFANQIGVTSVGEEDYVAQTGVIGGLRRGVTVKELTNAYATMGNKGVFNEAYMIRKITDSNGKVVFEHQLQSNPVFSEQTAYLITDMMRTVITSGTATDLMKTFKHYGKVPIVGKTGSTQDDADAWFMGYTPDITLGVWAGYDLPVHKLSKKTGGTNRAKNIWAMVMDTTIEKHPELFPTKTFERPADIVEMTVSSLSGKLPSNATSRAGKLTTDLFNKKYVPTEEDNVMVRLPVITYNGINYIAREGTPSDFVEEKSVIKRPEPLGKLFRELRSIISKLPADRKRSLDFYKPKDYAQDAPSETDPRKDDGNAPNAPTTVVATRSGESNVITFGASDSGDAVGYRLYRSVNGGSFQRVGGVVFAGDETKFTDTSSSGGTFGYYVTTVDVAGKESSPSKAAYTDGTTMDLLFGAGTGEPAKTEDDKKADSSDDKKSSEKESDDDKDSTPAPKSVPSIPSGVTVKSSGGGIELKWKANPEKEKVTQYNVYFSDKENGKYSKIGTVKGGTEFKYYAVSTEGYYIVSATNEAGESKSSVAVRSKK
>NC_017672.3|WP_014652218.1|6486801_6488061_-|tyrosine--tRNA-ligase
MDILSDLEFRGLINQVTDREGLAKKLAEEPVVLYAGFDPTADSLHIGHLLPLLVLRRFQQAGHIPVALVGGGTGLIGDPSGKAAERTLNPKEVVEEWTQKLRNQLSQFLDFEAQKNPAQTANNYDWLSELNVIGFLRDVGKNFTVNYMLAKDSVDSRLEKGISFTEFSYMILQAYDFQQLNEKRGCTLQIGGSDQWGNITAGLELIGKTNGNQAFGLTVPLVTKSDGSKFGKTEGGAVWLNAEKTTPYQFYQFWINTDDNDVVKFLKYFTFLSPDEIGELERQVKEAPEKREAQRVLAKEMTTLVHGAEAAESAIRISTVLFSGDVGSLSGSEIEQAFSDVPSTELEAGAEIALLDLLVQVKAAPSKRQARQDVESGAVSINGVKTTELDKVVRSADGLEGRFLVIRRGKRNYYLVKFQ
>NC_017672.3|WP_013917599.1|6486019_6486619_+|30S-ribosomal-protein-S4
MSRYTGPKFKLSRRLGISLSGTGKELKRPFPPGQHGPGQRKKMSGYGVQLQEKQKLRHMYGLNEKQFRNLFDKAAKMQGISGENFMFLLESRLDNLVYRLGLSNSRAGARQLVSHGHVTVNGKKVDIASYLVSTGDVIGLREKSRNLSAVKEALANRNYLPAYLEFNEAAVEGKYVRLPERSELAQEIDEKQIVEFYSR
>NC_017672.3|WP_014652217.1|6485106_6485691_-|TVP38/TMEM64-family-protein
MGEWDIQHLSDTLRSLGLIGQVSGALLILLQTIVPFVPFVVVAGANVLLFGFWLGFLVNYVFACLGAILAFYGTRSFGREWAQARLSKHRIAGRFNEKLGKHGLLYITLSRVTPVLPSFGINMAAAVMNVRSRDFILGTLIGKSPMILLESLIGHDLLHFTQYKGRLLVLLAVFGLLLAAGSYLNKRWTNSGAD
>NC_017672.3|WP_013917597.1|6483915_6485034_-|aminopeptidase
MRDPRLEQLARNLVEYSLDVQKGEKVLIDMIGSERELVKCLVEQVYARGGVPYVELIDPSVRAAVLKGATQEQIEHWTQMDLLRMKDMNCYIGVRAGENVSEMSDVPEEKMKLYSQIYSKQVHLEQRVKKTRWVVLRYPNASMAQLAGMSTSKFENFYFDVCNLDYAKMSLAMDPLQALMNRTDRVRIVGPGATDISFSIKGIGSVKCCGKRNIPDGEVYSAPVRDSVNGTIAYNTPSVSGGVTFENVTFRFEKGRIVEATANDTKRLNQILDTDEGARYIGEFSLGFNPHILYPMKDTLFDEKIDGSLHFTPGQAYEQADNGNRSSVHWDLVLIQRPEFGGGEIYFDDVLIRKDGRFVIPELEGLNPEHLK
>NC_017672.3|WP_013917596.1|6483548_6483797_-|HPr-family-phosphocarrier-protein
MANANNAAIVEISQTANKFRSSIVLQYDNKYIDVKSILGLFTTLLTTSNYDLHVHGPDAEEAKAAMAEVFQKHGLTINSIQD
>NC_017672.3|WP_014371489.1|6482785_6483073_-|YlaN-family-protein
MSSDVLLSLSQKALQLLQEDADKIEKLIEVQMENLTTRKCPLYEEVLDTQIYGLSREIDFAIRAELVQETAGKQILVKLERNLAALYEAMSQNKE
>NC_017672.3|WP_013917594.1|6481689_6482745_+|calcium/proton-exchanger
MIKRYGFTIGLVLSFLLSAVAHYIGEPAFSPTVQFFISAVAVIFVAGFLGKATESVAHYAGERLGGFLNATFGNAAELIIAIFLVRNGAFEVVKASITGSIIGNMLLVLGLSVLLGGLKFKEQTFNVKLAGHNSSLMLLAVIALFIPAAFTRSLTTLENEELSVIVSGILIVAYLLWLYFSMVTHKNELADEVVEHGEPAWSKGMSVAFLILATVMVAFESEWLVSTLEQFSHQFGLSELFVGAFLIAIVGNAAEHSAAILMARKNKMGAAIEIAIGSSLQIALFVAPLLVLLSLFFGNPMDLVFTTYELVAIGVAAFIASSISRDGNTTWYEGVLLLVVYLIIGIAFYLV
>NC_017672.3|WP_013917593.1|6481093_6481486_-|Asp23/Gls24-family-envelope-stress-response-protein
MSEELQTGLIRISDDVVATIAGLAALETPGIAAMSGGISEGLAKRLSGKNAQRGVSVEVGQVEAAIDLRVIVSYGSKIQEVCRDLQENVREAVENMTGLSVVEVNVKVEGVAFRDEETPAPVEDPLHRVK
>NC_017672.3|WP_016362870.1|6479850_6481038_+|putative-lipid-II-flippase-FtsW
MTPQRRGTPDFFLLFLTFSLVCFGLAFVFSAGMAFRKDDPWFLVFRQGLAVGLGTVAMFFCMNVDYRKFKKWLLPFFVVVVILLLLVPLIGAGADKGARSWIKIAGGFTLQPTEFAKLAVIIYLASIITKKGEKFQEFKRGLVPPLLVIGFISMLIMMQPDFGSTMIILLASAIIIVVGGANMRHVLYLGGAGLVFVVMVVSFYVLTADPGNYKIARLTAYLNPFSDERGSGYHLVHSLFAFGHGGWTGAGFGQSIQKLHYLPEAHNDFIFAIIGEELGFIGATLFLLVYLAFLLRGLVVALRCQDPFGTLVGVGIVSMMGVQAFINLGGVTNTIPMTGVTLPLISYGGTSMLTTLIGIGMLLSISREYNKPEQEVRRSTSVTHRSAAGYFTRGG
>NC_017672.3|WP_014652220.1|6492739_6494464_-|acetate--CoA-ligase
MDQTNVESIAPVTAQSNMKNYEEERAGFRWEDVEATFSWSQTGKLNAAYEAIDRHAESSRRDKVALYYSDDRRDEQYTYLEMKQQSNRFGNVLKGLGVGKGDRVFIFMPRTPELYFALLGAIKVGAVVGPLFEAFMETAVRDRLEDSEAVAIVTTPSQLSRVPVDQLPHLKHVILVGEDLTLEAGQVDFRKEMESASDELELEWLDREDGLLIHYTSGSTGKPKGVFHVHNAMLQHYYTGRVVLDLQEDDVYWCTADPGWVTGTSYGIFAPWLNGATNVIRGGRFSPQDWYRTIERYGITVWYSAPTAFRMLMGAGDDAVKQFNLGSLRHVLSVGEPLNPEVVRWGLKVYNQRIHDTWWMTETGGQLICNYPCMAIRPGSMGKPLPGIEAAIIDDSGNVLPPYRMGNLAIKTPWPSMMRKIWKNPAKYEEYFRIQGWYISGDSAYMDEDGYFWFQGRIDDVINTAGERVGPFEVESKLVEHPAVAEAGVIGKPDPMRGEIIKAFIALREGYTPSDELKADISRFVKEGLSAHAAPREIEFKDKLPKTRSGKIMRRVLKAWELNLPTGDLSTIED
>NC_017672.3|WP_014371492.1|6494606_6495239_+|GNAT-family-N-acetyltransferase
MNHIKIYQQSSVPYQNTELVLEGPVPPEQLRRYTMHPDLDAFRRPKEQFEALVEIAGLPEGRIILARHEEVIVGYVTFHYPDELERWSEGGMLDLIELGAIEVANAYRGLGLGKKLIRLAFEDGQLENVITFTTEYYWHWDLESSGLTVWQYRDMMEKLMKSVDMVWFATDDPEICSHPANCLMVRIGKNVPLSSVELFDRVRFRQRFMY
>NC_017672.3|WP_014652221.1|6495238_6496435_+|acetoin-utilization-protein-AcuC
MGAQEAMERQALFIFDENETAYRFSDEHPFNQKRLLLTVDLLRRAGALPASCLEPPMPVDPEKLCTVHAKEYVEAVIALSHPMPDEAWMRRAATYGLDTEDTPFFHGMHEATSTVVGGSVQAVDAVMTGRTPHALHLGGGLHHALSGKGAGFCVYNDASVAIEHAKCEYGARVLYIDTDVHHGDGVQWSFYTDPDVCTFSIHETGKYLFPGTGAVQERGEDSGFGTTVNVPVEPYTEDESWLECFGDVLVKVIAQFKPDLIVSQHGCDAHAFDPLAHVHCSMEIYRAMPALIHRLAHEYCEGRWVALGGGGYDIWRVVPRAWSLLWLEMTDHPLRDVLQADAGLPLPEDWVTAWQPFSEEPLPPTWLDPVHTWTPMPRRAEITAKNRQTKEIAMLYLK
>NC_017672.3|WP_013917606.1|6496658_6498041_-|glycine--tRNA-ligase
MSVTMDQITALAKHRGFVFPGSEIYGGLANTWDYGPLGVELKNNIKRAWWKKFIQESPYNVGLDAAILMNPQAWVASGHVGNFNDPMIDCKQCKVRHRADKLIENALGEKGIEIIVDGMTFADMEKLIAEHKIVCPDCGAMDYTDIRQFNLMFKTFQGVTESSANVVYMRPETAQGIFVNFKNVQRTMRKKVPFGIGQIGKSFRNEITPGNFTFRTREFEQMELEFFCKPGEDLQWFEYWRAFCRDWLLKLGISENSIRLRDHNEDELSHYSNATTDIEYKFPFGWGELWGIADRTDYDLKQHMSHSGEDFNYIEQETGERYVPYCIEPSLGADRVTLAFLIDAYEEQQLEGDDSRTVLHFHPALAPYKAAIFPLSKKLSEGAHKVFADLAKHFLVDYDETGSIGKRYRRHDEIGTPFCITYDFESETDGQVTVRDRDTMEQTRMPISELRAFIESKLEF
>NC_017672.3|WP_014652222.1|6498084_6498789_-|5'-methylthioadenosine/adenosylhomocysteine-nucleosidase
MTYGKIGVIGAMKEEIELFHEGMKGVTQTVKAGITFYEGTFHDRSIVLCKSGVGKVNAAVTTQILIDTFGVEAVLFTGVAGAVDPGLDVGDIVVSTECLQHDMDVTALGFPRGTIPYEATSLFAADEKLRKLAAEVSAELFGARVKEGRVLSGDQFISSRETVSQLYTELSGACTEMEGAAVAQACSMNGIPFVIIRSMSDKADGSAHVNFAEFTQQASENSFRIIDGMLQRLQ
>NC_017672.3|WP_016362873.1|6498912_6499935_-|catabolite-control-protein-A
MAVTVTIYDVAREAGVSMATVSRVVNNNPNVKPQTRKKVFEAIERLGYRPNAVARGLASKKTTTVGVVIPDISNSIFSEVARGIEDIANMYHYNIILCNADKKKEKEIRVINTLLEKQVDGLLFMGGAVTEDHIQAFKTSSVPVVLCATADEQRVIPSVDIDHEKAAFDAVNVLLQSGHTKIAMISGTLQDPANGYARYQGYRKALEAANIPIDEDYVRIGNYRYESGMDVTKHFLELDERPTAIFAATDEMAIGAIHSLQDSGLRVPEEMSVISVDNIRMASMVRPQLTTVAQPMYDIGAVAMRLLTKLMNKETKDASELTQVILPHEVIHRNSVAQRS
>NC_017672.3|WP_013917609.1|6500348_6500768_-|hypothetical-protein
MQKLCKCGNQMNIRLRTVMYQNKVEIENVPIFSCESCSRNEVFAEIKPELTGLIGSLGGKPGKQQVHFDEISEVAHLMVKVTEKNRASDPVESIIRERINELLDLLLLAQSLGDEAWAQDVRGRLEQITKHSLAVQDLT
>NC_017672.3|WP_013917610.1|6500954_6501368_-|hypothetical-protein
MILAIRWVPAVLWMAVIYYFSSKTGDDLDGWLDVLHRWLPALQSFDFGHFISYLVLSWTFVWAFRPKRLTLAVMLGIVLLCFLYGITDEYHQSFVPRRSVSLMDLRNDVIGAAVGMALLHIPPLRRLYARAVDAKYY
>NC_017672.3|WP_013917611.1|6501364_6501898_-|type-1-glutamine-amidotransferase
MELKGTRVLAFVDEEFEDLEMWYPVMRLREAGAEVHLAGPKSGTVYHGKYGVPLTTEYAIDEVKSEDYIGLYVPGGWAPDKLRRYASVLRLTREFHEAQKPIAHICHAGWVLASAKICQGYTMTSTPGIKDDLENAGAIWVDEEVVVDRNIVSGRRPPDLPAFSKAFVDVLAAYRNR
>NC_017672.3|WP_014652226.1|6501944_6503840_-|phosphoenolpyruvate--protein-phosphotransferase
MVEGIGASPGIAMGKAFVIPTWEWDFPDKLIDVTDLAYEFERLYDGIRHSKSEIEQIKQEFVSVLGEEQTQIFDAHLAILEDPIFMSEVQGIMQRQYKAAEVAVKEAIEKFVNMFDLLDDTYMKERALDIKDVGNRLLKHLLGALEETLPPKDQPYVLVAKELQPSQMVHLDVNQALGVVTMLGGKTSHVAIMARAMGVPYVLGLEGKLASPIQTGDYLIIDGDEGIVYVNPGEPVVERYKARKANWNAMQESLQKLAHLPSRTRDGVQVNLAANISSVKELAHVMGSNASGVGLFRTEFLYMDRSTFPLEEEQYAVYREVAERLNGRPVVIRTLDVGGDKNLDYLALPEEENPSLGYRAIRISLDRTDLFKTQLRAILRASHYGRIKIMYPMISSLDELRRANLVLDEAKRELDEEGLPYRPDIEVGIMIELPAAVMISELLAQEVDFFSIGTNDLVQYVLAVDRMNEQVAHLYDPFHPAVLRMLKLTADNARLHGTHVSVCGELAGDIRALPIWLALGITELSMSVQSILKVKNSLLQSRGSDGPQIWRELAPCPSSAAVTEVLGRYMKSGLAGEEAETDSGPSAAGNAAQAPDSGAPGSAPPSKGSGEGRKEEPKDPVPPPYPAGEYC

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_9

6798231-6798419

Orphan

Consensus_repeat	Method
ATAGCGCATCTGAGTTCCGTTATTT	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_017672_9

>merge|NC_017672|9|6798231-6798419|CRISPRCasFinder
ATAACGGAACTCAGATGTCTTATTTGCCTGAAAACGAAGCCCTCGCAGCAAATAGCGGAACTACGATTCTTTATTCCGCCTTTTATGCCAGCAGAACCCCCTCTAGGCGTACAATAGCGCATCTGAGTTCCGTTATTTTCATTTTTACCTTGCATTGGGCCCCGATAACGCATCTGAGTTCCGTTATTT

>NC_017672|9|7|6798231-6798419|CRISPRCasFinder
ATAACGGAACTCAGATGTCTTATTT	GCCTGAAAACGAAGCCCTCGCAGCAA
ATAGCGGAACTACGATTCTTTATTC	CGCCTTTTATGCCAGCAGAACCCCCTCTAGGCGTACA
ATAGCGCATCTGAGTTCCGTTATTT	TCATTTTTACCTTGCATTGGGCCCCG
ATAACGCATCTGAGTTCCGTTATTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_128758995.1\|6787494_6788046_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NC_017672.3\|WP_014371700.1\|6788326_6789052_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NC_017672.3\|WP_014652323.1\|6802310_6803342_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187575
NC_017672.3\|WP_014652324.1\|6803522_6804041_-\|DUF3231-family-protein	unknown	unknown	gnl\|CDD\|371599
NC_017672.3\|WP_014652326.1\|6804752_6805232_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_016362895.1\|6804187_6804751_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013919693.1\|6809176_6810925_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|182732
NC_017672.3\|WP_013917892.1\|6789727_6790642_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237974
NC_017672.3\|WP_014371703.1\|6793650_6793860_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_041618502.1\|6798918_6801768_-\|glycoside-hydrolase-family-81	unknown	unknown	gnl\|CDD\|227785
NC_017672.3\|WP_014652317.1\|6793944_6794868_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|316372
NC_017672.3\|WP_014652321.1\|6797070_6798090_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_017672.3\|WP_014652328.1\|6806614_6808603_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_017672.3\|WP_014371715.1\|6813396_6814164_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_017672.3\|WP_016362896.1\|6810962_6813083_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_017672.3\|WP_014652320.1\|6796287_6796575_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_017672.3\|WP_014652327.1\|6805428_6806388_-\|acetylxylan-esterase	unknown	unknown	gnl\|CDD\|368448
NC_017672.3\|WP_013917891.1\|6789341_6789728_+\|response-regulator	unknown	unknown	gnl\|CDD\|381097
NC_017672.3\|WP_014652319.1\|6795397_6796180_-\|DUF3891-family-protein	unknown	unknown	gnl\|CDD\|379025
NC_017672.3\|WP_014652318.1\|6794864_6795398_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_128758995.1\|6787494_6788046_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	5.95195e-43
NC_017672.3\|WP_014371700.1\|6788326_6789052_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	7.09287e-39
NC_017672.3\|WP_014652323.1\|6802310_6803342_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187575	cd05265, SDR_a1, atypical (a) SDRs, subgroup 1. Atypical SDRs in this subgroup are poorly defined and have been identified putatively as isoflavones reductase, sugar dehydratase, mRNA binding protein etc. Atypical SDRs are distinct from classical SDRs. Members of this subgroup retain the canonical active site triad (though not the upstream Asn found in most SDRs) but have an unusual putative glycine-rich NAD(P)-binding motif, GGXXXXG, in the usual location. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.81898e-68
NC_017672.3\|WP_014652324.1\|6803522_6804041_-\|DUF3231-family-protein	gnl\|CDD\|371599	pfam11553, DUF3231, Protein of unknown function (DUF3231). This bacterial family of proteins has no known function.	1.5608e-25
NC_017672.3\|WP_013919693.1\|6809176_6810925_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|182732	PRK10789, PRK10789, SmdA family multidrug ABC transporter permease/ATP-binding protein.	1.02548e-179
NC_017672.3\|WP_013917892.1\|6789727_6790642_+\|hypothetical-protein	gnl\|CDD\|237974	PRK15489, nfrB, glycosyl transferase family protein.	0.00146871
NC_017672.3\|WP_041618502.1\|6798918_6801768_-\|glycoside-hydrolase-family-81	gnl\|CDD\|227785	COG5498, ACF2, Predicted glycosyl hydrolase [Cell envelope biogenesis, outer membrane].	2.35564e-125
NC_017672.3\|WP_014652317.1\|6793944_6794868_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|316372	pfam13847, Methyltransf_31, Methyltransferase domain. This family appears to have methyltransferase activity.	3.17063e-22
NC_017672.3\|WP_014652321.1\|6797070_6798090_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.55033e-96
NC_017672.3\|WP_014652328.1\|6806614_6808603_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	8.06169e-59
NC_017672.3\|WP_014371715.1\|6813396_6814164_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.17419e-149
NC_017672.3\|WP_016362896.1\|6810962_6813083_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.52011e-169
NC_017672.3\|WP_014652320.1\|6796287_6796575_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.18397e-07
NC_017672.3\|WP_014652327.1\|6805428_6806388_-\|acetylxylan-esterase	gnl\|CDD\|368448	pfam05448, AXE1, Acetyl xylan esterase (AXE1). This family consists of several bacterial acetyl xylan esterase proteins. Acetyl xylan esterases are enzymes that hydrolyze the ester linkages of the acetyl groups in position 2 and/or 3 of the xylose moieties of natural acetylated xylan from hardwood. These enzymes are one of the accessory enzymes which are part of the xylanolytic system, together with xylanases, beta-xylosidases, alpha-arabinofuranosidases and methylglucuronidases; these are all required for the complete hydrolysis of xylan.	1.58103e-168
NC_017672.3\|WP_013917891.1\|6789341_6789728_+\|response-regulator	gnl\|CDD\|381097	cd17542, REC_CheY, phosphoacceptor receiver (REC) domain of chemotaxis protein CheY. The chemotaxis response regulator CheY contains a stand-alone REC domain. Chemotaxis is a behavior known for motile bacteria that directs their movement in response to chemical gradients. CheY is involved in transmitting sensory signals from chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY, which causes counterclockwise rotation of the flagella, resulting in smooth swimming. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	8.81859e-38
NC_017672.3\|WP_014652319.1\|6795397_6796180_-\|DUF3891-family-protein	gnl\|CDD\|379025	pfam13030, DUF3891, Protein of unknown function (DUF3891). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are approximately 250 amino acids in length.	1.20563e-74
NC_017672.3\|WP_014652318.1\|6794864_6795398_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.38895e-11

>NC_017672.3|WP_014652321.1|6797070_6798090_+|LacI-family-transcriptional-regulator
MNIKTVAKLAGVSVSTVSKIINNYSDISAETREKVLGIMKETGYIPSNSAKTLATKKSGLIGVVFAGKLNIDFTHPFFVGVLNAFKRQMGLLGYDLLFFSNEKFHASGEDYLARCRHFQVEGCILLSGQELEPAIHELDRSPIPCIGVDLMLSGASSGHIMSDSERMAAQVVEHFYLLGYRDIGYLGASAYYHISSMREAGLLKSLDRWGLPVQPDWFIHGDDFSESSGCEAMKRLIAGGSLPRALFAGSDHLAIGAIRALMEHGLQVPVDVAVIGCDDVEAARYVSPPLTTIRQNKDKIGKIAAMMLYDLINNQMRSSSVLVEPELIVRASCGARREG
>NC_017672.3|WP_014652320.1|6796287_6796575_-|GNAT-family-N-acetyltransferase
MRYTGEVWEPRRIICGLIAEEEGRAVGFGSMVIKNRFWQESYVGRITALVVEERMRGRGIGRTLIEELSRDRGGERVQEGGARFGVSPGGSPPFL
>NC_017672.3|WP_014652319.1|6795397_6796180_-|DUF3891-family-protein
MIVRDTGDAWVLTAQHEHARLSGDAARRFRPFFEGDPHFEDLVTAVYQHDLGWVRLDETPVWNDRASAPYSFIDYPLLPKLTHYRLGLDQVEELNPYAALLCSMHYAAFVEGSTDEESSAFHRYETGRQERIRKELGIRGAKELQKPFSLLKLCDRISLYVTLNEPGAGKAQEYPPYRTGFGQSEPFHPDGTGILAARWISKSEIEMAPNPFGHTFRTSVRQKRVPKALAGVIGLAEAYGRTEETEQEVVFHGRTGEEEA
>NC_017672.3|WP_014652318.1|6794864_6795398_-|GNAT-family-N-acetyltransferase
MASVRPLGPEDAEAFLKLRLEALREHPAAFSADEADWRSKSVEEAALLLSGARGSFVLGAFDAEGELVGMAGFQPNDKPKLSHKGTLWGMYVTARVRRQGAGRALVEALLNRARLLPGIRRVNLGVIRTDGGAGRLYASAGFQVYGTEPRSLHYDGTFYDEDLMYFEWEDGETGRLP
>NC_017672.3|WP_014652317.1|6793944_6794868_-|class-I-SAM-dependent-methyltransferase
MTAEKKWVWDDRYDYLRDTRDLYYNEDYLEFLVRIVWKLDRPVDMIDFGCGYGYLGLKLLPLLPEGSTYTGIDRSGELLKRARDAFQGTFYSAEFVEADLEGEVELDRRYDLAVCHALLLHLPDPVRTLGRMAGCVREGGRLICFEPHWIGGMAGHQSGEGDASEVVPLGVLQKLYEDGRQRTGRDGNIGLKLPAYFSRLGLRNVECRVSDKVNFLDPRSGERERQELFHALKQEGLGTMPGERGAFVQGLLDRGLSLREVEVQYEAERLYAERFQVDSPLAYAPGMKITFGTVGPQRIEGSSFLNF
>NC_017672.3|WP_014371703.1|6793650_6793860_-|hypothetical-protein
MQTFLDDEGQLMQRTDKLMDVSLNVVGKATAHYHNIRRAVHRNSEQIDKSFRSIDQARTLIETARRSLR
>NC_017672.3|WP_013917892.1|6789727_6790642_+|hypothetical-protein
MFAQYFGQYLLSQGHLTSTQLYEALTAQKDARPKLGVLAINHGWMTGSQVEEVHAEQMSRDKRFGEIAVEQGYLTEEQVQELLLSQKSEHLLLGQTLIDQGLMTYDSFSEVLGAFKEAYSLSSDQFSSILQGNVDALVSAVLLKDGLPAGEWLSGYVSLFAKNLIRFADTGVRLEMAIAPRPSVYDWVFSQEITAEGTAEAGYTAVAGSQESMLRLASRFAQETISAPDELFEAAAGELLNLHNGIFLVNMSDRGTELSMEPQHTARSIPEDTLAKLQAIRIYGTDYEVDLLISDLTPLLRQPS
>NC_017672.3|WP_013917891.1|6789341_6789728_+|response-regulator
MNPKEVKIMLCDDSLLVRKKLKSALEEQGYTGILEASDGLEAVALCREQKPDLVLMDIVMPRKDGIEALKEIKEFDKSIHVVMVSSVGTQGNLIKALKAGADNFMQKPVTIEALNELIHKMAQDRREA
>NC_017672.3|WP_014371700.1|6788326_6789052_-|Crp/Fnr-family-transcriptional-regulator
MQTATKQTMTERPYHIPQFLSSANMERLEKVMVLQRASEGSHLFWEGDTADKLYFVKKGAVKLMKSTEDGRSIILQIAQAGDLFGEFGDPGAMSFGYDAVVLAEATLGVIALSDLENLMRSSGDFAVEFVKWQSLMQRAAQTKLRDLLLYGKSGALAATLIRLASSCGIRTERGVRISMRLTHTDLAHMIGSTRESVNRLISEYRAEGALDFQKGYITVKDEAFFKDMVGGTDIPLELCRI
>NC_017672.3|WP_128758995.1|6787494_6788046_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MVYWIIRNAVKLWLYLRFRIQVKGVRHIPEGGCILAMNHRSNYDSLLVGVHTPRKMHIMAKEELFRSKLGAWVITEMGAFPVKRGSADLRSLKHSLKLIEEGGLLSLFIEGTRSQSEEMGDPKKGIGFLVAKSRAPVVPVLIQGAAGGWFSRATVTFGEPLVPESRDYEDIARQVAGAIKQLA
>NC_017672.3|WP_041618502.1|6798918_6801768_-|glycoside-hydrolase-family-81
MKKKMLSLALSAVLAAGLLPGTGQAFTGEVPLGAGSYSTVLPAGAADVQAQIYKTGNVTGKMPTNDWWSSLAWVQYSEAQYPHPLAVKNQSDGFRIYNPSGRITANSSCVCGWINDIHDFTVGHTGSGTFPDAKVDGFSDWFVKAQYQNGASSMNVSYGHGSPYVYFNFGGGNPQLKFYTPPTVWSGSAGSSVLGITIEGAHYGLFGPTGSTWSGIGTNTLTNALNGKTYFSIAALPDNTAATLNKFKQYAYSHVTDTKISYGYNAAAGEVTTTFNYTTSAKEGTQTGTIFALYPHQWKNSSQALLPYTYNSVRGTMKTGEGASFTTRMKFTGVLPALPDKGTYNKTTLGGYINEEEALAYTGGTDTYWLGKRLGKLATLAPIADQVGDSTASAKFRSEIKSRLQDWFKASDASGHLKGSNVFYYNNNWGTLIGYPASFGSDGELNDHHFHYGYYIKAAAEIARTDKAWAQSWGPMVELLVRDIANWNRSDTMFPFLRNFDPYAGHSWASGHARFGDGNNNESSSEAMNAWAGLILWGEATGNTTIRDLGVYLYTTEMNAINDYWFDVQDNTHPAAYTPSVVTMIWGGKGANATWFTANPEQVHGINWLPITAGHLYLTHYPSYAAKNYNALVSENGGTNWDIWRDLIWMYRAISSPADAKNQFAAGVGSMATGGAEGSGGPETGNSKANAYHWIYNLDAMGNADPAITANSPTAAVFNKGGVKTYVAYNFSNSAKTVTFSDGTSVSVPANSFNTGNGGGTGGGDTVAPSAPSGLVSTGKTSSSVSLSWSASTDNVGVTGYTVSYGGNSLNVTGTTATVSGLAAGTAYTFTVTAKDAAGNVSAASSAVTVTTDSAGGGGVITTPDYTASVTKTSATQAKIAFTPTVNALYVDVHYTVNGGPQLNYRMTKNGSTWEQPVDGLSAGSVLKYWFTYEKSGPQYDSPQYTYTH
>NC_017672.3|WP_014652323.1|6802310_6803342_-|NAD-dependent-epimerase/dehydratase-family-protein
MKLLVLGGTRFVGYEVVLSALSRGHEVTTLNRGQTAKGVHSGVKELYGDRDGGLDVLRGGTWDAVIDTCGYLPRLVRASGQELADRVGVYTFISSISVYKDLSVPLNHENSDVRELEDESNEDIPNHYGALKARCEQILEGLMPGRVLTVRPGLIVGPRDLSDRFTYWPVRISRGGEILCPGQGDSEVQFIDVRDLAEWTVAMTEARRTGVYNAAGPGVRLTMRELLERAREALGSSAVFTWCGESFLAEQGVRGWSDMPVWLPAEGELSEFRGMLQADYSKAVQAGLTFRPVEETVRDTVRYHGHRGEGDAWKAGLSAARERELLALWHGGKAGERRDGGHG
>NC_017672.3|WP_014652324.1|6803522_6804041_-|DUF3231-family-protein
MGILSGNPKHEPMHYGEIHQVWQFSMAAKGCISATELYRNHAGDRTLKTILGDILDQARLESKECDELLMHNGIMPAPALPARPEVELESIPAGARFGDPEIAAMIAADQSVGLVACSQVMGMSIREDIGALFAKYHATKAAISVRILRMNKEKGWLIPPPLQVKSEDLVKV
>NC_017672.3|WP_016362895.1|6804187_6804751_+|hypothetical-protein
MSRHPRLGGSLQIRTPIIRPAGERPMSLDHAFLLAIAVSAVAVLFFGIPRSQIREALITFTCFQALTWPVGFAITGLGWITYPVRIFPLATDLGFLFDYLFCPAVFTLFQVRYPQNRPLMVQGAYYAVYAVGVALLQSWIADHTGLIDFKRWTAYNSILLYLAEYWVARRYVIWFLRRWAPSLRGER
>NC_017672.3|WP_014652326.1|6804752_6805232_+|hypothetical-protein
MYTTERIILGAANLGALLSLFLLPRGKVLQHHLVFLAVGLPTWVIGLMVVEWGLLAYPVRELAAINRTSFCFEYFLLPIVAVHYNAWYAENKPLRVRARYLLLYCSALTVPEMLIERYTDLLSYLHWSWYITFLSEGLVFLYSRAILLWFFRPSSHRMS
>NC_017672.3|WP_014652327.1|6805428_6806388_-|acetylxylan-esterase
MPLLDMPLGQLQTYQGRNPRPDDFDAYWEKALEEMRNVDPQVELVPSSFTVPFAECFDLYFTGVRGARIHAKYIRPKGVDTPHPAVLHFHGYTGSSGDWQDKLSYAALGFAYASLDVRGQGGLSEDTGGVKGTTHNGHFIRGLDDEPQNLLFRHIFLDTAQLASIVMGFPEVDAGRVGATGWSQGGALTMACAALEPRIKKAAPVYPFLSDYRRVWEMDLAKDAYAELRTYFRHFDPQHQREEEIFTKLGYIDIQHLAPRIKADTLAGVGLMDPICPPSTQFAAFNKMTAPLKLELFPDFGHEGLPGMNDKIYQFLKEL
>NC_017672.3|WP_014652328.1|6806614_6808603_+|methyl-accepting-chemotaxis-protein
MNKWFGKSIRAKIIVLLLSVTMIPLLIACSLLMAISTGAMETSTKVNQTALAQLSAASIDTWLKGKITSAQRVIDAHPEFKQGNPAQIVPILKVLTEADPDVQAFNFVTSTGASHRIDGSVVDVSKFDNFKTAQSTMKTAVSDIRKSAATGENVIIIDVPFKKDNGEFAGLLQMLLSPADLISMVSSIKEGSGYGYLLSSTGTYLIHKEVERVGKPAGELLGDAAAAFENSVLKNTNGTLNYTEADGASYAAAYDAVASTGWKMVIIAPEKEVYAEVNRTRITTIAIIVISLIVVTGIALVVARIISTPLLRISSLMKEVAQGRLVDRLEVRGEDEIQTLKAHINHMLDSFCELIGKISESSEIVAASSEELTATSLQTAAATEQVNRSVSFIATSSEAQYESASQTSMTMTEMAVGITRIAESASGVSEATNEVVSDVTSGHAEVQAAIRQMTAVGGTVRQTANAVQSLEQQSHTIGEIIDVIRGIAQQTNLLALNASIEAARAGEHGKGFAVVATEVKKLAEQTRTEAERITVIVSSILDNTRTVASSVNEGVEMMNEGVGQVSKVGEIFEHVLASVRSVSDQVQEVSAASEELSAGTEEVAASMSEMLHVTKEAAEQLAQVSRTASEQKQSMDEVSNSSQSLSEMAMELREMVSRFSTK
>NC_017672.3|WP_013919693.1|6809176_6810925_+|ATP-binding-cassette-domain-containing-protein
MLTVLYKLRWFFRQHWRRYTAAILLLTVAGVIDVIPPKLIGYSIDGIHQGTLGGTHFYGILALWAAITVIGYAINYVWMCQLFGGAFVLERTLRTSLMKHLLRMTPTFYERNRTGDLMARATNDLRAVSTTAGFGILTLIDSSIFMLTILITMAGFISWKLTLASLLPLPVMALLIQQFGGRIHKRFTEAQEAFGQMNDSVLETIGGVRVIRAFVQEQASREQFGEMTRHVFHKNAEVARIDALFEPTVKILVGLSYLIGLCYGAYLVFHGELTLGELVSFNVFLGMLIWPMFAIGELINIMQRGSASLDRVNETLAYEPDVPGPAAPAAVARPETLAWNGLTFRYPSSPIDNLVDITFELQRGQTLGIVGRTGSGKTTLLKQLLREYPSGSGSLTVSGTPIEEIDLDVLHGWIGYVPQQPILFSRTIRENILFGRSGAGDAELDRALELASFRKDIAFLPEGLQTLVGEKGVALSGGQKQRVSIARALIADPEILMLDDALSAVDAKTEAEIIAGIRRERAGRTTLITTHRLSAVQHADLILVLDEGRVTEAGTHEELLALGGWYKEQYDRQQLESAAAGA
>NC_017672.3|WP_016362896.1|6810962_6813083_+|ABC-transporter-ATP-binding-protein
MNTDSRRTGARLFRYAMLFRRPILTALVLLTLAACAELAGPLIAKRMIDRHILGIEMAWYETPGPGESTAAYSGKHYKRSDHWLPGEKPGTEVRIVQSGMGYYFAEGPFASDGTRTVDTSAPDAPLLTVTSPSGERSTYPARQLTAPELYAFYAPEFRPLLMLAAGYFGLLVLSALFTYGQRYLLQISANRVIGRMREDVFAQVQRLPIQYFDNLPAGKVVSRITNDTESIRELYVAVLANFFSGIIYMTAIVGALFLLDTRLALIALPLFPLLYLWIKVYRRFAERYNEEIRSRLSDINGMINEAIGGMPIIRAFRQGRQTMEEFETLNGEHYTYQNKLLSLNSITSHNLVNVIRNVIFLGVIWMFGGGLLGAAVTVGVLYAFVDYMNRMFQPIVGIVNQLSNLETALVSANRVFELLDQEGTDVAEGRLDRYRGDVSFESVSFAYKENDYVLKEIGFEARQGQTVALVGHTGSGKSSILNLLFRFYDPQHGRITIDGRDIRDIPRQLLRQHMGIVLQDPYLFTGTIASNVSLGDPNISREKVEKALRDVGAYDMFSALPGGIDEPVIEKGSTLSAGQRQLISFARALAFDPAILILDEATASIDSETEAVIQSALEVLKRGRTTFIIAHRLSTIKNADIILVLDRGQIMERGNHAELMARKGRYYQMYLLQSGEALDGGRAEAAADAGREAAAPPAAAVPSTLS
>NC_017672.3|WP_014371715.1|6813396_6814164_-|amino-acid-ABC-transporter-ATP-binding-protein
MTSSNAMLEMKQLTKSFGPAQVLKGIDLTLEQGKVLAIIGPSGSGKTTLLRCMNLLETPSGGTLRIGDLALDFGGAQLPKQGQVLQLRKKTGMVFQAYNLFPHMTVLQNVMEGPVTVQKRPKEEARTRALELLRKVGLAEKADAYPHELSGGQQQRVGIARAMAMEPELLLFDEPTSALDPELVGEVLKVIKALALEGRTMVIVTHEMKFAGEVADRVILMDDGRIVEEGSPDEVFHRPSSERTKLFLSRLQTQA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_10

6874423-6874523

Orphan

Consensus_repeat	Method
ATGTGCCACCTCTAGGAGCAAGC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_017672_10

>merge|NC_017672|10|6874423-6874523|CRISPRCasFinder
ATGTGCCACCTCTAGGAGCAAGCCGGCTATATATATCACCTCTCCTTCAGCCTTCAATGGATCATCAGCCTTTGCTTTACGTGCCACCTCTAGGAGCAAGC

>NC_017672|10|8|6874423-6874523|CRISPRCasFinder
ATGTGCCACCTCTAGGAGCAAGC	CGGCTATATATATCACCTCTCCTTCAGCCTTCAATGGATCATCAGCCTTTGCTTT
ACGTGCCACCTCTAGGAGCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014652373.1\|6887022_6887907_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NC_017672.3\|WP_014652360.1\|6865771_6867382_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NC_017672.3\|WP_014652370.1\|6879871_6880840_-\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|226449
NC_017672.3\|WP_014652361.1\|6867378_6868092_+\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NC_017672.3\|WP_014652359.1\|6864442_6865495_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270234
NC_017672.3\|WP_016362905.1\|6878327_6879644_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270303
NC_017672.3\|WP_013919742.1\|6863827_6864289_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815
NC_017672.3\|WP_014652358.1\|6862287_6863814_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225870
NC_017672.3\|WP_014652371.1\|6882852_6885258_-\|glycoside-hydrolase-family-95-protein	unknown	unknown	gnl\|CDD\|379625
NC_017672.3\|WP_013919752.1\|6873040_6873961_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226652
NC_017672.3\|WP_014652365.1\|6870771_6872124_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274819
NC_017672.3\|WP_013919760.1\|6881219_6882140_+\|helix-turn-helix-domain-containing-protein	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|226652
NC_017672.3\|WP_014652368.1\|6875254_6876295_-\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350138
NC_017672.3\|WP_013919756.1\|6877314_6878244_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NC_017672.3\|WP_014652372.1\|6886461_6886752_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238640
NC_017672.3\|WP_013919755.1\|6876464_6877310_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_017672.3\|WP_013919740.1\|6861943_6862192_-\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|376329
NC_017672.3\|WP_014652364.1\|6869041_6870496_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_017672.3\|WP_014371749.1\|6885545_6886388_+\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|224007
NC_017672.3\|WP_013919748.1\|6868421_6869045_+\|LysE-family-transporter	unknown	unknown	gnl\|CDD\|280058

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014652373.1\|6887022_6887907_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	5.00325e-25
NC_017672.3\|WP_014652360.1\|6865771_6867382_+\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	3.16593e-179
NC_017672.3\|WP_014652370.1\|6879871_6880840_-\|family-43-glycosylhydrolase	gnl\|CDD\|226449	COG3940, COG3940, Predicted beta-xylosidase [General function prediction only].	0
NC_017672.3\|WP_014652361.1\|6867378_6868092_+\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.28478e-83
NC_017672.3\|WP_014652359.1\|6864442_6865495_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	4.28858e-86
NC_017672.3\|WP_016362905.1\|6878327_6879644_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.37995e-54
NC_017672.3\|WP_013919742.1\|6863827_6864289_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	3.70611e-10
NC_017672.3\|WP_014652358.1\|6862287_6863814_-\|hypothetical-protein	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_017672.3\|WP_014652371.1\|6882852_6885258_-\|glycoside-hydrolase-family-95-protein	gnl\|CDD\|379625	pfam14498, Glyco_hyd_65N_2, Glycosyl hydrolase family 65, N-terminal domain. This domain represents a domain found to the N-terminus of the glycosyl hydrolase 65 family catalytic domain.	1.13476e-88
NC_017672.3\|WP_013919752.1\|6873040_6873961_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|226652	COG4189, COG4189, Predicted transcriptional regulator [Transcription].	6.37742e-117
NC_017672.3\|WP_014652365.1\|6870771_6872124_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274819	TIGR03860, FMN_nitrolo, FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family. This model represents a distinctive clade, in which all characterized members are FMN-binding, within the larger family of luciferase-like monooxygenases (LLM), among which there are both FMN- and F420-binding enzymes. A well-characterized member is nitrilotriacetate monooxygenase from Aminobacter aminovorans (Chelatobacter heintzii), where nitrilotriacetate is a chelating agent used in detergents. [Unknown function, Enzymes of unknown specificity].	0
NC_017672.3\|WP_013919760.1\|6881219_6882140_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|226652	COG4189, COG4189, Predicted transcriptional regulator [Transcription].	1.02014e-120
NC_017672.3\|WP_014652368.1\|6875254_6876295_-\|family-43-glycosylhydrolase	gnl\|CDD\|350138	cd18817, GH43f_LbAraf43-like, Glycosyl hydrolase family 43 such as Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43. This glycosyl hydrolase family 43 (GH43) subgroup includes characterized enzymes with alpha-L-arabinofuranosidase (EC 3.2.1.55) activity. It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. Characterized enzymes belonging to this subgroup include Lactobacillus brevis (LbAraf43) and Weissella sp (WAraf43) which show activity with similar catalytic efficiency on 1,5-alpha-L-arabinooligosaccharides with a degree of polymerization (DP) of 2-3; size is limited by an extended loop at the entrance to the active site. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	0
NC_017672.3\|WP_013919756.1\|6877314_6878244_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.40121e-70
NC_017672.3\|WP_014652372.1\|6886461_6886752_-\|hypothetical-protein	gnl\|CDD\|238640	cd01315, L-HYD_ALN, L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in biotechnology). But L-HYDs differ by having an L-enantio specificity and by lacking activity on possible natural substrates such as dihydropyrimidines. Allantoinase catalyzes the hydrolytic cleavage of the five-member ring of allantoin (5-ureidohydantoin) to form allantoic acid.	0.00979928
NC_017672.3\|WP_013919755.1\|6876464_6877310_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.4412e-76
NC_017672.3\|WP_013919740.1\|6861943_6862192_-\|HPr-family-phosphocarrier-protein	gnl\|CDD\|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	4.78968e-11
NC_017672.3\|WP_014652364.1\|6869041_6870496_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	1.33153e-118
NC_017672.3\|WP_014371749.1\|6885545_6886388_+\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	8.87086e-33
NC_017672.3\|WP_013919748.1\|6868421_6869045_+\|LysE-family-transporter	gnl\|CDD\|280058	pfam01810, LysE, LysE type translocator. This family consists of various hypothetical proteins and an l-lysine exporter LysE from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators. LysE exports l-lysine from the cell into the surrounding medium and is predicted to span the membrane six times. The physiological function of the exporter is to excrete excess l-Lysine as a result of natural flux imbalances or peptide hydrolysis; and also after artificial deregulation of l-Lysine biosynthesis as used by the biotechnology. industry for the production of l-lysine.	4.49693e-27

>NC_017672.3|WP_013919752.1|6873040_6873961_+|winged-helix-turn-helix-transcriptional-regulator
MLYIKDLKTGLNIFKALGSDIRIEILELLAKNQSLNLNEIATRLKLTNGAITMHIKKLEESGLIEIGTAVGKHGVQKICYLTEEKLIVDLRSKETDNLYEVDIKVGHYSNYQAVPTCGLATKDSIIGDFDEPRYFADPQRIDSEIIWLSEGFLEYRIPNYLKPNQDFAEIQLSMELSSEAPGYNNNYPSDIYFYLNDMELGSWTSPGDFGDVRGTFNPDWWPPHLNQYGMLKLIRINEEGSYIDGCRISDVKLSDINLDYKSDLNFRIEVGEKSKNKRGMTIYGKNFGNYNQDLLVRVMYTERDID
>NC_017672.3|WP_014652365.1|6870771_6872124_+|LLM-class-flavin-dependent-oxidoreductase
MSSPRSQLHLNLFLAPLGHHEAAWRHPGSEPRRLTEFALYQEIVRKAEASKLDSIFLADRVAASPESLRHGAVGGLEPLTLLSALSVVTSRIGLIGTVSTSFNEPFNLARRLASLDHLSGGRAGWNIITSGTDGEARNFGLDEIPGHAVRYERAREFLEVAVKLWDSWEDDAVLADQAAGLFADTSKVHPVRHEGTYFRVDGPLNLQRSPQGRPLLVQAGSSEDGRSFAAEYAEAIFTAQQTLADAQAFYADVKARAARFGRDPQTVKILPGICPVIGDTEEEAREKEARLHELSNPQHSLLQLSNRLGIDLTGYPLDAPFPELPEPGEVRGHQSRARLIAELARSEGLTLRGLLERLAGGRGHRTFTGTPVQVADQLEAWFRGGAADGFNVMPQLTHEGLPDFLDKVVPELQRRGLFRTEYSGSTLREHYGLSRPASLYAAKPAPSLPG
>NC_017672.3|WP_014652364.1|6869041_6870496_-|amino-acid-permease
MSKGKTSSKDDKLKWWQLSLLGVACTIGTGYFLGTGIALTMGGPAVIFLFILAAFGTYMVFDALARMTAADPQQGSFRSYAKKAYGRWAGFTSGWVYWSSELLIMGSQLAALSLFTRMWFPNLPMWMFAAVYGLLGLGIILLGTKGFERLENMFAVMKIAAILMFLVLAGAALFGMLGQGAYAPKVPATGPEVWPGGGIGLWSAFIFAFYAFGGIEIMGLMAMRLKNPKEAPKAGKMMILLLTTVYIASLVCAVILVPIGAFNSKESPFASALNHYNLPFVPHVFNSVLIIAGFSTMVASLFAVTTMLVTLAGDHDAPKMFSAKKDSSKLPFTAIGFTAGGLAVSVVTALLMPESVYEYVTTAAGLMLLYNWTFILVTSGRLLKLSGWGQTKRWSGILLIALAVVGTLFHETSRPGFFISLGFVAVISVVTLIMRRVWKKQRGGGGESGPKGRSKHAEGQQSGHDEYEPSVNRPVLPRRRKSFT
>NC_017672.3|WP_013919748.1|6868421_6869045_+|LysE-family-transporter
MSVILSYIFLGLSLSAPIGPINAAQLDKGIRCGFWHAWLVGLGAMMADALYMIMVYMGLVHFLSTPLIQTLLWSFGSFMLIYTGIDSLLGASSVAVVTKKKDDTLFKSFFSGFLMSLSNPLTILFWLGIYGSVLAKTASVYGTQQLLVYSSAILVGILVWDFSMAGMASTFRRLMTPRLLTGISVISGLSLIGFGLYFAVAACRLLF
>NC_017672.3|WP_014652361.1|6867378_6868092_+|response-regulator
MNEQPSHEITVLIVDDDPKIAEINRRFVEKVPGFSVIGIATDESQAREQLEILGPQLVLLDIYIPNSNGIDILQQIRRHHRDTEVIMITAAKEIEPVREAVRSGAFDYIIKPLVFNRLRETLLRFRDFQQQLQRLGSGGGQVAQDDIDRLLARTDKKEGPSSAPLPKGIDKLTLDKVVGALSSTPEGMTADGVAKLIGVSRSTGRRYLEHLVSLGDVYADLSYGVVGRPERVYRSRR
>NC_017672.3|WP_014652360.1|6865771_6867382_+|sensor-histidine-kinase
MRLQNKLILVICSLLALVTLSLGGTFYYLMNSALEEQIGTRALKVAETVAAVPDIRKAFTLAEPSAVIQPIAESIRLKTGAEYIVIGSREGIRYSHPLPERIGKEMVGGDNGPVLEGRSIVSRAVGSLGPALRGKTPVKNESGDVIGIVSVGFLTKDIDVLTETYRYRIVWLTLGVLLVGAIGAVLIARSVRSSIHGLEPREIGSLYMEKQAILETIREGILAVNREGVVTLANPYALRLLGLPEHSDITGRPLQELLPNTRLTEVISSGQAEFDQEMLIGSHEVIVNRVPITGWNGGIEGAVSSFRSKSELYRLAEELSQVRRFADALRAQTHEYSNKLYLISGLIQLEAYQEAVDLIARESDVHQNLVAFLMREIPDPMIGGLLIGKYNRSRELKVIFEIDRESSFRDLPPGVDRSLLVTVIGNLADNAMEAVLACGDPAGRGVKLFLTDLGEDLIIECEDTGIGIPDEAGDSVFAKGFSTKEGEHRGIGLALVQHAVHKLGGYITYQPHPGGGTVFTAAIPKNGRGTERRALQ
>NC_017672.3|WP_014652359.1|6864442_6865495_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MMNRMMNRAWKVTAAGVLAASLTACGAAKQQPAAGGDAAQTPAQTASKYPEKAITLVAPSGAGGGWDMTARTITKVLSEMKAVAKPMSVENKPGGGGAVFMAEYATKDVKDDHKLFVSSPPILINHIKKEGNSPYGIKDTTPLAQLTKDYGAIAVAANSKYNDLKSLLDDMKADPTKLTVAGGSAPGSMDHIVAILPAFKYGIDPKKVKYVSYDGGGEAVTALLGGNADVLGTDASSLDQYVKAGKIKILAVAAPQRLENMKDIPTMKEQGVDAEFLIWRGIFGPKNMSADAKKFWEDTLGKMVESEQWKKEVAANNWQTEYKKSEEFKSFLTAQETQLKDILTALGMQK
>NC_017672.3|WP_013919742.1|6863827_6864289_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MNKTFDRYAGIVFLAVGAAFAVGSGTISTSAYGSNVGANIFPMVLGIFLALMSIRLIYETFRYQQRQKRKENLDYKRFGIIFTAAVLYAFFLEDIGFVLGTFLFLMLGFQTMERGRIWVSLLISAAFSFGVYYLYVHVLEGSLPGFPAWLGLT
>NC_017672.3|WP_014652358.1|6862287_6863814_-|hypothetical-protein
MGTIDYLMNGLATAMQWHNVLFVFFGVLIGTVVGVLPGIGPMSGVALLIPITASLTAGLGPEEAATSSIILLAGVYYGAMYGGSTTSILLNTPGESSSVVTTLDGYQMAKQGRAGAALSIAAIGSFAAGLVALIGLIFLANPLSAIAIKFGPAEYFSLMVLGLLAISGLAGKSMTKALMMTALGLLLATIGIDNVSGVARFTFDLPELYQGLEFLTVAVGLFAVGEVFKTILHREGNEGEIARINGILPTKQDLKDSAAPIARGSLLGFAVGLLPGAGAILASFFSYIMEKKLSRNPSKFGKGAIEGVAAPESANNAAAGSAMIPLLTLGIPSSGTTAIMMGAFIMYNVQPGPLLFQDHPQLAWGVIASMFVGNLMLIILNMPMVKIFAKVIETPTKYLIPLIIVFSVFGVYAVQYSIFDLLLVMACGLIGYYLSRNDFPLAPLVLGLILGPMMENNMRRALTISNGDFMIFLQKPISLVFLIVGALWILVPLVLKLRGKNVLVNEEG
>NC_017672.3|WP_013919740.1|6861943_6862192_-|HPr-family-phosphocarrier-protein
MSGIEPRAIVEINQTASRYTSSIVIRVDNRSIDAKSILGLSFTLFGSQAYKLEIYGPDAEEAKAAMTEVFEKHGLSVEVLEG
>NC_017672.3|WP_014652368.1|6875254_6876295_-|family-43-glycosylhydrolase
MGLSLLAAGCSQAGGNTPGASEGKSGAKEEAIEWNNPLVEQRADPFVMRHTDGYYYFTASVPEYDRIEVRRAKTLGELAKAETVTVWQKHENGPMSKHIWAPEIHHIDGKWYIYFAAGRTNAPFDHRIYVLENASANPLEGTWTEKGQLKTDWESFSLDATTFEHKGTRYLVWAQKDPSIYGNSNLYIAPMANPWTLGGRQVRISQPEYDWEQIGFWVNEGAAVIQHGGRLFMTYSASATDANYAVGLLTASESADLLDPKSWTKSEKPVFATSEENGQYGPGHNSFTVSPDGKRDIMVYHARSYKDITGDPLYDPNRHARAKYVTWNADGTPNFGVPLPDTKQEK
>NC_017672.3|WP_013919755.1|6876464_6877310_-|carbohydrate-ABC-transporter-permease
MPQTKSWSVQSVLLLLLFAAIAVFTLFPIYALFLASFKPSQELLRYGLNLRFDTELMSLKNYAFIFSGDASNYFGWYTNSLVITVLATLLCLLFSSMVGYGLAVYDFKGRNLIFVLVLIVMMVPVEIILLPLYKLIIGLRMMDSIWGVILPFMVAPLPIFFFRQYAEGLPKDFLDAGRIDGCSEYGIFFRLMAPLMAPAFGAMAILQGMGAWNNFLWPLIVLKSNEKFTLPIGLATLLTPYGNNYDILIAGSVLAILPILILFIFFQRFFVSGLTVGGVKG
>NC_017672.3|WP_013919756.1|6877314_6878244_-|sugar-ABC-transporter-permease
MKNHTVAIQAVEKKRSGSLAYNQRLAPYVFVAPFLITFILFFAYPVASTVLMSFQEVLPGQTKFIGFDNYKKLLNPTFYKAIANSAKYTVLTLLVLIPLPLVLAVFLNSTFMRGKNFFRSTLFVPALTSVVVAGTVFKLVFSELDSALANTFIGFFGIEPQKWLGQSSTALLVLVLLATWRWLGVNIIYFLSGLQSIPTELYESADIDGANTWDKFVKITLPLLKPVTIYVLTISIYAGFAMFTESYMLYNGNRSPKDMGLTIVGYIYQQGLEKNNLGLGSAIGLTLLGITMFINLVQLKITGQFRKGD
>NC_017672.3|WP_016362905.1|6878327_6879644_-|sugar-ABC-transporter-substrate-binding-protein
MKKAHGLMLATTLLLSSLATACSSGGETAKPDANAGGAAAGGKTKLQFWTFNELHQKYFVSMAEAWNKAHPDKAIQLEASTLPFDDMHNKLLVALQSGTGAPDISDIEISKFPNYLKGTPQLAELNTVVEPELKNIVKSRVDIYSKDGKYYGIDYHVGASVIYYNKEMLDKAGVNPDSITTWDEFYEAGKKVVAATGKPMITFEATDPFSFWPMIAQQGSDITDKAGKVTLDNEKNIAVLQYMQKLVKEKIAIVAPGGFHHAEEYYGFMNKAGAASIAMPMWYMGRFTDYMPDLKGKLVIKPMPAWTKGGNRSVGMGGTGTAVTAQSKNKELAAEFLAFAKLSKEANIQIWKQLGFDPIRTEVWTAPELKEDNKFTQYFGKDIFDVMIEIKDEIGPINVNEKMPEVNDELKKTTLFKALNDMEDPAKVLKESADQLRK
>NC_017672.3|WP_014652370.1|6879871_6880840_-|family-43-glycosylhydrolase
MITSYKLRNPLIEQRADPWIYKHTDGFYYFTASVPEYDRLEIRRSETIEGLTSAEPVVVWRKYDTGPMSANIWAPEIHYVQGKWYIYFAAAKTTETVEGLFDHRMFVLECDAENPLEGEWIEKGQLKTDWESFSLDATSFEHNGTQYLVWAQRDPEIPGNSNLYIAAMSNPWTIIGPQVMLTKPEYDWEVIGFLVNEGAAVIKKNGKIFISYSASATDHHYCMGLLSASETADLLDPASWTKSPVPVFQTSEENGQYGPGHNSFTVAEDGVTDLLVFHARSYKEIVGDPLYDPNRHTRVQVLEWNVDGTPNFGVPLPDTKEE
>NC_017672.3|WP_013919760.1|6881219_6882140_+|helix-turn-helix-domain-containing-protein
MLYIKDLRSGLPIFKALGSDIRLAILDLLAQHQSLNLNDLAKALQLTNGAITMHIKKLEESGLIEVTTAVGRHGIQKLCYLSEEKLMVDLRSKELENLYEVEIKVGHYSDYQASPTCGLATKDSIVGDFDDPRYFADPGRIDAQMVWLTEGYLEYRIPNYIKAHQTFKEIQFSMELSSEAPGYNNNYPSDIFFYLNGHEIGSWTCPGDFGDVRGKYNPDWWPPHVNQYGMLKLIRITEDGSYIDGCRISDVTLAQIGIDDKSDLQFRIEVGEKSRNRKGLTLYGKHFGNYKQDLLVRVLYSEPYAS
>NC_017672.3|WP_014652371.1|6882852_6885258_-|glycoside-hydrolase-family-95-protein
MKLTYDKPARVWTEALPAGNGRLGAMVFGGMEHELLQLNEDTLWSGAPGDHNNPRAREVLPEVRRLALEGRYREADRLCKEMLGPYTQSYLPLGDLSLRFHHGDHAGDYERHLDVEGSILRTSYRIGAVTYTRELFVSHPDQVLVLRLTTDRPGALSFTAKLDSALKHRTAADAGDLVLKGRAPVKVDPNYYRTDEPVRYAEGDAGGGMRFEARLRVQADGAELQVDGGALHVERATEVTLLLTAATSFNGYDKQPAEQGRDESRAAANDLRAASGLTYEELLQRHQDDYRALFGRVTLSLGASRAPEGMPTDRRITEYGASDPGLAELLFHYGRYLLISSSREGTQPANLQGIWNKEVRAPWSSNYTLNINAQMNYWPAETCNLSECHEPLLGFIGRLAVNGAKTVSVNYGLRGWTAHHNSDIWAQSAPVGAYGHGDPVWAYWPMAGAWLSAHLWEHYAFCREEDYLREQAYPVMKEAALFCLDWLVEDADGFLVSAPSTSPEHRFVMAEGELAAVTAAATMDLALVHDLFTNCIEAARTLGTDVEFSAGLQDALDRLQPLQIGQYGQLQEWKRDFEDEDVHHRHVSHLYGVYPGRQLTAEDSPDLFQAARQSLERRGDAGTGWSLAWKICLWARFGDGNRAHRLIGNLLSLTSEYEAGGQRGQQGGVYPNLFDAHPPFQIDGNFGYTAGVAEMLVQSHTGVIRLLPALPDAWPDGEVSGLRARGGFEIGLSWQAGRLAEARIRSLAGGLCRLQAEGSFLLLGGEGEPLSAEAGDGGTAAFPTEAGRTYVLRPVTSGAAI
>NC_017672.3|WP_014371749.1|6885545_6886388_+|sugar-phosphate-isomerase/epimerase
MSKPGILAHNFGRLPLEELADRVAGAGLASVQLALAKALSDVDSATGKLSPGLANHVGEAFAKRGVRIASLGCYINPVHPDPEQRKQELRRFKEHLRFCRDFGASVVATETGKLDTFKADEPERYEEKAFETLRSSVLELAEEADKWGVTVGIEPAYTLVIHSTEGMQRLLEEVPTSTLGVVLDPCNLLNASLLDRQQEIVSAAFDALADRVVLFHAKDIRKTASGGTEYTPLGTGELDYPHFLRLVKERKPHCHITMEGLEPDQIAPSLDFFRKVWNEV
>NC_017672.3|WP_014652372.1|6886461_6886752_-|hypothetical-protein
MDYYQHAVLDTEEKFALMIIIISSFDDALSGGHAPGGVWERIRRCLAEDIDIHVNTIHYWALHGEDLEDGFAVTPYIRTLLEIQGIQEERIETSTD
>NC_017672.3|WP_014652373.1|6887022_6887907_+|AraC-family-transcriptional-regulator
MQSSTPQGVYGFRFQDTPGDAFYQLFALGHEVRSGPSYSWDGLQRSDGPLLLLQYTVSGHGFLEAGGRVHRIGPGQAFLVDIPSRHRYYASPEGEPWEFYFILLRPYGLETHWKHITERTGPAADIPPDSPVVHLLQDAFHAAARGRITDGYLASSLVYRLVMELLRFSSARRRDKEHWPPAIRTAALRLEADYASLPGMEEIAKEAGMSASHFTRSFHRATGYTPVEYLTKIRIEASFDLLRRSSLPIEEVAKAVGYSGGSYFSRVFREWVGFSPGDFRSGREVTALQHVTFD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_11

6947386-6947460

Orphan

Consensus_repeat	Method
AATAGCGGAACTCCAGTGCCTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_11

>merge|NC_017672|11|6947386-6947460|CRISPRCasFinder
AATAGCGGAACTCCAGTGCCTTATCCGGTTATTTCCCGTTATTTCCCGGAGAATAACGGAACTCCAGTGCCTTAT

>NC_017672|11|9|6947386-6947460|CRISPRCasFinder
AATAGCGGAACTCCAGTGCCTTAT	CCGGTTATTTCCCGTTATTTCCCGGAG
AATAACGGAACTCCAGTGCCTTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_013919826.1\|6956402_6957269_-\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350095
NC_017672.3\|WP_013919817.1\|6949569_6951999_-\|exoglucanase-A	unknown	unknown	gnl\|CDD\|227616
NC_017672.3\|WP_164923365.1\|6955788_6955932_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350095
NC_017672.3\|WP_014371778.1\|6941901_6942501_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NC_017672.3\|WP_013919810.1\|6940821_6941661_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NC_017672.3\|WP_013919815.1\|6945863_6946880_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_017672.3\|WP_014652390.1\|6947710_6949450_-\|cellulase-family-glycosylhydrolase	unknown	unknown	gnl\|CDD\|365907
NC_017672.3\|WP_014652388.1\|6936903_6937629_+\|DUF1361-domain-containing-protein	unknown	unknown	gnl\|CDD\|369208
NC_017672.3\|WP_051220088.1\|6935122_6936736_-\|glycoside-hydrolase	unknown	unknown	gnl\|CDD\|119353
NC_017672.3\|WP_014371780.1\|6943316_6944030_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_017672.3\|WP_013919820.1\|6953186_6953618_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NC_017672.3\|WP_014371781.1\|6944093_6945686_-\|glycoside-hydrolase-family-28-protein	unknown	unknown	gnl\|CDD\|227721
NC_017672.3\|WP_014652389.1\|6937768_6939028_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|372371
NC_017672.3\|WP_014652392.1\|6953659_6954142_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380217
NC_017672.3\|WP_013919822.1\|6954117_6954996_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293840
NC_017672.3\|WP_013919819.1\|6952580_6952997_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319899
NC_017672.3\|WP_013919823.1\|6955027_6955423_-\|DUF5071-domain-containing-protein	unknown	unknown	gnl\|CDD\|213039
NC_017672.3\|WP_013919809.1\|6939122_6940208_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236329
NC_017672.3\|WP_013919812.1\|6942562_6943156_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NC_017672.3\|WP_013919824.1\|6955446_6955635_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_013919826.1\|6956402_6957269_-\|family-43-glycosylhydrolase	gnl\|CDD\|350095	cd08981, GH43_Bt1873-like, Glycosyl hydrolase family 43 protein such as Bacteroides thetaiotaomicron BT_1873. This glycosyl hydrolase family 43 (GH43) subfamily includes Bacteroides thetaiotaomicron VPI-5482 endo-arabinase (Bt1873;BT_1873), as well as uncharacterized enzymes similar to those with beta-1,4-xylosidase (xylan 1,4-beta-xylosidase; EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanase and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the GH43 enzymes in this family may display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	5.78718e-178
NC_017672.3\|WP_013919817.1\|6949569_6951999_-\|exoglucanase-A	gnl\|CDD\|227616	COG5297, CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) [Carbohydrate transport and metabolism].	0
NC_017672.3\|WP_164923365.1\|6955788_6955932_-\|hypothetical-protein	gnl\|CDD\|350095	cd08981, GH43_Bt1873-like, Glycosyl hydrolase family 43 protein such as Bacteroides thetaiotaomicron BT_1873. This glycosyl hydrolase family 43 (GH43) subfamily includes Bacteroides thetaiotaomicron VPI-5482 endo-arabinase (Bt1873;BT_1873), as well as uncharacterized enzymes similar to those with beta-1,4-xylosidase (xylan 1,4-beta-xylosidase; EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanase and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the GH43 enzymes in this family may display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	6.35209e-16
NC_017672.3\|WP_014371778.1\|6941901_6942501_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	7.50964e-38
NC_017672.3\|WP_013919810.1\|6940821_6941661_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.12942e-25
NC_017672.3\|WP_013919815.1\|6945863_6946880_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.51965e-112
NC_017672.3\|WP_014652390.1\|6947710_6949450_-\|cellulase-family-glycosylhydrolase	gnl\|CDD\|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	5.34384e-76
NC_017672.3\|WP_014652388.1\|6936903_6937629_+\|DUF1361-domain-containing-protein	gnl\|CDD\|369208	pfam07099, DUF1361, Protein of unknown function (DUF1361). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins.	3.73983e-32
NC_017672.3\|WP_051220088.1\|6935122_6936736_-\|glycoside-hydrolase	gnl\|CDD\|119353	cd02874, GH18_CFLE_spore_hydrolase, Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.	3.28294e-33
NC_017672.3\|WP_014371780.1\|6943316_6944030_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.83123e-27
NC_017672.3\|WP_013919820.1\|6953186_6953618_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.39547e-13
NC_017672.3\|WP_014371781.1\|6944093_6945686_-\|glycoside-hydrolase-family-28-protein	gnl\|CDD\|227721	COG5434, PGU1, Endopygalactorunase [Cell envelope biogenesis, outer membrane].	1.27468e-85
NC_017672.3\|WP_014652389.1\|6937768_6939028_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|372371	pfam12897, Aminotran_MocR, Alanine-glyoxylate amino-transferase. These proteins catalyze the reversible transfer of an amino group from the amino acid substrate to an acceptor alpha-keto acid. They require pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze this reaction. Trans-amination reactions are of central importance in amino acid metabolism and in links to carbohydrate and fat metabolism. This class of aminotransferases acts as dimers in a head-to-tail configuration.	0
NC_017672.3\|WP_014652392.1\|6953659_6954142_+\|hypothetical-protein	gnl\|CDD\|380217	NF033218, anchor_AmaP, alkaline shock response membrane anchor protein AmaP. The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version PF03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.	0.00576022
NC_017672.3\|WP_013919822.1\|6954117_6954996_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293840	cd16282, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.65724e-36
NC_017672.3\|WP_013919819.1\|6952580_6952997_-\|VOC-family-protein	gnl\|CDD\|319899	cd06588, PhnB_like, Escherichia coli PhnB and similar proteins. The Escherichia coli phnB gene is found next to an operon of fourteen genes (phnC-to-phnP) related to the cleavage of carbon-phosphorus (C-P) bonds in unactivated alkylphosphonates, supporting bacterial growth on alkylphosphonates as the sole phosphorus source. It was originally considered part of that operon. PhnB appears to play no direct catalytic role in the usage of alkylphosphonate. Although many of the proteins in this family have been annotated as 3-demethylubiquinone-9 3-methyltransferase enzymes by automatic annotation programs, the experimental evidence for this assignment is lacking. In Escherichia coli, the gene coding 3-demethylubiquinone-9 3-methyltransferase enzyme is ubiG, which belongs to the AdoMet-MTase protein family. PhnB-like proteins adopt a structural fold similar to bleomycin resistance proteins, glyoxalase I, and type I extradiol dioxygenases.	5.31191e-31
NC_017672.3\|WP_013919823.1\|6955027_6955423_-\|DUF5071-domain-containing-protein	gnl\|CDD\|213039	cd11743, Cthe_2751_like, Uncharacterized protein domain similar to Clostridium thermocellum 2751. Cthe_2751 has been found to form homodimers. Based on structural similarity to other families, a role in processing nucleic acids was suggested, though interactions with DNA could not be demonstrated.	2.20927e-49
NC_017672.3\|WP_013919809.1\|6939122_6940208_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|236329	PRK08664, PRK08664, aspartate-semialdehyde dehydrogenase; Reviewed.	0
NC_017672.3\|WP_013919812.1\|6942562_6943156_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.68093e-15

>NC_017672.3|WP_013919815.1|6945863_6946880_-|LacI-family-transcriptional-regulator
MKATIYDVAREAGVSIATVSNAIRGKGKISPKKREEILEIVERLQYQPSMIASALTGKRTYTLGLLVPDISNPFFGEIARAVEERGQQLGYSVIICSTDNKDERVERYISLLEQKSVDGIIIGTGISDASLLERLSSRSVPVAMIARDLPSADVHKVVIDDYLGGVLAARHLLELGHRRFGVISEKHNRERIRGFCETVERSGQALSPCGIRIFGDDDQIQDGGRAAAELLELEARPTALFCCNDMSATGALRAAKARGLAVPRDISIVSFDNTILSEVCDPPMTTIAQPMEEMGRLVVDALLQELGDGGAKQRFVLQPELLVRGSTAAFVPEEQKNA
>NC_017672.3|WP_014371781.1|6944093_6945686_-|glycoside-hydrolase-family-28-protein
MSSIEPIVSGSSWTLSEVGQPSIPDRSFSVTDYGAVGDGVTDNTEAFHKAIAACSQAGGGRVVIPAGVWLTGPLSLASRLDLHAQAGALVLFSRRFEDYPMIFSQYEGQPSIRCQSPLDGEGLEHVAITGAGVFDGGGDAWRPVKDWKMTEKHWAKLIASGGVVDEDAGMWWPSEAAMNGPAKVAQLKREGSTDPKDYEAARDYLRPNLLSLRRCKYVLLEGATFQNSPAWNLHPWACEHVTLRGVTVRNPWYGQNGDGLDLDSCRYGLVEDCSFDVGDDAICIKSGKDEAGRALGIPCEDILIRNCRVYHGHGGFVIGSEMSGGVRRLRVEDCTFMGTDIGLRFKSTRGRGGLVEDIEIERIRMNSIVGEAISFHLFYEGKEGSGVAGENIVPVSVETPIFRGITIRDVQCAGAETALLINGLPEMPLDGLVVENFTASAKRGGVCTNAQNLTLKDVTLHVEQGPVVSLRHAQHVKIEGLGGSAPEGSDMLQVSGRGSKEIAYGGIRLPEELRGVKIAVEVEDKNSIRG
>NC_017672.3|WP_014371780.1|6943316_6944030_+|alpha/beta-hydrolase
MQMQMQTQVKQVELNGLLFQYRETGKISSPPIIALHAMGMTAETWDEAAAVLGETHRVLALNQRGHGGSARTGSYTFELMCEDMLAFADRMGLERFILLGHSMGGTVSYLFSQTYPSRVERLLVEDTPPPFAGKRFDIPPEPSEPLPFDWAVVPSIIGQLNEPDPQWWARLPAIQAPTLIIGGGVSSPIPQDKLKEVSGLIPICKLVTVDGGGHHVHSTRLPAFLAAVQSFLKDEPV
>NC_017672.3|WP_013919812.1|6942562_6943156_-|TetR/AcrR-family-transcriptional-regulator
MPRTPQENERIRGMAKEKIRAAAIEVFIEKGFHKASIDDVAKKAGISKGLLYNYFKGKTDLLAELVHTRKEEIVQVMEEAVRQASPKEQLLYIAEHALRSVERQPHVYRFYLHLQTHPEADEVVSAYSQTLKDEMARQAEVQAEIFRNLNAARPELESLQFSTMLHGIMLMYSSYPNGFPLEELKHDMVTSFINRYA
>NC_017672.3|WP_014371778.1|6941901_6942501_+|histidine-phosphatase-family-protein
MAAELYLVRHAKKEKGIGDAAISSEGMRQAQATARHFRGLPITQILCSPLQRAKMTAAIIAKGTGTVLTEDHRLRERANWGDIPGQTFEDFVEMWDRCTLDRDFSPPAGDSARQAGERLASCLLDLSASHPQGPLLVVTHGGLITDFLVQVIPEAELNKLHPRFIAEQSRLVAECSITTVRCEDGRFSLVDFAAVEHLL
>NC_017672.3|WP_013919810.1|6940821_6941661_+|AraC-family-transcriptional-regulator
MTERTGFKYTIGDTAFAIQQLQQTGVTSMPRPHSHEFYELYYLFHGERVYFIGGKVYTARKGDLMVVVPNDLHSTASSAVAEFERMLVHFSPSFLGEEGPGLMELPPFRESTLLSIPMKEQPELEHLLLQLHTECREQQPLYEACVRHLLGELLVRIHRRGLIEQEPPESVHPMHQKVTEIASYIHGHYQEDLTLGGVAKQFFISPAYLSRVFLKLTGFHFSEYIRVVRVREAQKLLRTTREKVQSISEQVGFEHISHFNKTFKRIAGLSPLQYRDQHR
>NC_017672.3|WP_013919809.1|6939122_6940208_-|aspartate-semialdehyde-dehydrogenase
MSAKLKVGIVGGTGMVGQRFMQLLDQHPWFEVTAIAASAGSAGKTYEESVQGRWKMDGPIPEEVKSIVVQDASKVEEVASGVDFIFCAVDMKKAEIQALEEAYAKTGTPVISNNSAHRWTPDIPMVIPEVNPGHIEIIEAQRKRLGTSTGFIAVKPNCSIQSYVPALNALLDYQPKVVVASTYQAISGAGKNFTDWPDMLDNVIPYIGGEEEKSEQEPLRIWGSIQGGEIVKASAPLITTQCIRVPVTDGHMATVFASFEKKPAKDEILDRWRTFKGRPQELGLPSAPEQFITYFEEDNRPQTKLDRDIYGGMGVSVGRLREDTVYDYKFVGLSHNTLRGAAGGAVLIAELLKAEGYIQAK
>NC_017672.3|WP_014652389.1|6937768_6939028_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MESQPAFVHWESEELRDHHRRLTQRYEACRSQKMALDMSRGKPCPEQLELSREMLGIVAADDPLRAADGSDCLNYGGIDGIPEAQSLFARMLGVESKEILIGGNSSLTMMHDALTRAMLHGVYGSERPWGRLPKVKFLCPSPGYDRHFAICELLQIEMIVVDMLPSGPDMDQVERLVREDDSIKGIWCVPKYSNPDGITYSDAVVDRLSQMKTAAADFRIFWDDAYTVHHLTPEPDVLKNILAACRAAGNPDRVFLFCSTSKITFPGAGVAVLASSENNLGLIRRQLAVQTIGPDKINQHRHVRFLRDMDHLKTHMERHAAIIKPKFDLVLRKLEEELADKQIASWHKPNGGYFISLNTLDGCADEVVRMAAEAGVTLTKAGATFPYGKDPRNRNIRIAPTYPSLTELETAIDILCLCV
>NC_017672.3|WP_014652388.1|6936903_6937629_+|DUF1361-domain-containing-protein
MEGTIMNLNRLLPWVPLLTLLSLVTAACLLLSSRLGEAYDFLRWDVTLAWIPVPMALLFMLLDGLKARWVRRLLRALVAAVWLAFFPNSAYLVTELLHAFRFFEMQPGFWTGIDYWYRVMPIFGVACLGLALSASSLYLLHRWTSARLGALTGWFFAAAALALASFGVYIGRILRWNSWDLAARPQMIVTELAALYQDTSRWSHAVSFVELFFAVLFLSYGIFYTAIVLGAKGSPAPASLQ
>NC_017672.3|WP_051220088.1|6935122_6936736_-|glycoside-hydrolase
MTLLSLIQKTIPAAALLLLAATGSALAYDVSLKPFTDVSNGDWFQEEVYSLSAIGLIDGYPDATFQPDGMLTREAFLKLLVQSKSLDPAVPSGDAPADVEPSRWSYPYIAAAYERKWIDVLLDSRRALDPQRTITRGEVAAVAGRALLDAQPQEARERWMSQGWQEERERRKYADGDTIGEGLRPYAYYAVNRGIMEGDETGFHPQQPLTRKEAAAIFYRLIDAETAGAKLEHTGFYAIRSYPAIGRIPLLSQVTFGWSHLEYPSPGTARLNTEKTEYRIPSGWEEALGAAGSAKAGKELMVYYGDKNLKDFLKDEGAQNAFIDSLKAVLTDKKYGFSGVCMDLEGLLEPASAADYVQFLHRVKKSIPDYKLTVAVQPDYYYKGYDLKEIGGLADTVILMAYNFTHDESRLPSAPLPLVNDSVKRALALVPKEKLVLGISKQANQWVTAPDGGTDSFNPEIAEVEKRLGAPGVSQSMSYPYFLKRMVFQDERGSHEMYYEDTESIQKKLWLAKYYGLKGVSLWYMGNYTDSDWKLFE
>NC_017672.3|WP_014652390.1|6947710_6949450_-|cellulase-family-glycosylhydrolase
MKPFRLWGAWLSTAVAVLGLMLPFGAAYSQAAAAVPYGQLKVQGADLLGESGQRVQLRGMSSHGIHWYGDLVNPGSLKWLKEDWNSNLFRVAMYTAEKGYITDPSVKEKVKEAVQAAIDLGLYVIIDWHILTDGDPNTYKTQAKAFFQEMAALYGQYPNVIYELCNEPNGNVTWAGQIKPYAQELTQAIRAIDPDNIIIVGTPNWSQDVNQAADSPLPYGNIMYAAHFYAGTHGQWLRDKIDYARSKGAAVFVTEWGASDASGDGGPFLREAQEWIDFMNSRGISWANWSLADKEETSAALLPGANPSGGWPASQLSASGQFVRSKLRESLVSVPAAPAGLQAAPGSGQAALSWNAVNGATGYIVKRAAVSGGPYTTVAELTGTSYTDTGLANGTTCYYVVSAKNAAGTGPVSAQVSVQPAAGQGGGGTPVPGSLVLQYRAADTNAGDNAIKPHFNIRNTGASPVDLSGVKLRYYFTKDGIQPLSFAVDWAQVGSPNVKGTFGSASGAGADTYLEVSFTGGSIPAGGQTGEIQTRIHKSDWSSFQESGDYSYDPGKTSYADWSKVTLYRDGTRVWGVEP
>NC_017672.3|WP_013919817.1|6949569_6951999_-|exoglucanase-A
MRNSVWRKMSSVLAAAALLGGLLPAGAATSYAAEAHVDNPFAGATAYVNPDYAAQIDTSIAKVSDPALQAKMETLKSYPTAVWLDRIAAIGGGASNGGRRSLEGHLDAALAQKKGTAPITATFVIYDLPGRDCHALASNGELPLTQEGLQRYKTEYIDAIASIFANPKYRDIRIVTVIEPDGLPNLVTNLSDPKCAAANSSGIYIAGFQYALNKLHAIPNVYNYLDIGHSGWLGWDDNRRGAVTLYTNAVKGTTAGLASVDGFITNTANTTPLVEPYLTNPNLSINGQPIRSSKYYEWNPNFDETDFTAALYADFTAAGWPSTLGFLVDTGRNGWGGVNRPAGASGSDIDTYVNSGRIDRRAHRGLWCNNNGAGIGLPPQNAPAGYAASHIDALVWVKPPGESDGASKFIPNDEGKLADPNCDPTYTNADGVLTGAMPDAPLAGHWFHDQFVMLVQNAYPAIPGSGGGTPAVPAAPVGVKAAEGNAQVTLTWDASAGAASYTVKRASVSGGPYTTVAAGLTATSFTNTGLTNGTVYYYIVTASNAAGESAASVQVSAVPSSGVSVPAAPAGLTAAAGNAQVTLTWSASAGATSYTVKRATVSGGPYTTVATGLAATSYTNTGLTNGTAYYYVVSAVNSAGESANSAPVSAVPEGSVTPPAGSLAVQYRAGNTNAADNAISPHFNIKNNGTAAVNLSDLKIRYYFTKDGSAGLDSWVDWAQVGGANVQRVFSSASGTGADTYVEISFTAAAGSIPAGGQTGDIQLRMAKTDWSNFNETGDYSFDGTKTAYANWDKVTLYQGGKLVWGIEP
>NC_017672.3|WP_013919819.1|6952580_6952997_-|VOC-family-protein
MAKHNTYFFSEDARAQADFYVQALGGEIQAVMTNGQLPEAAEGTKDKVIHLSMVAAGVNFCLADAEYGPVSSGNAVSQCLTFATEAEAREAFEKLSEGGTVSQPLEPAFWGALFGQLEDKFGVQWMITTESQECQTPA
>NC_017672.3|WP_013919820.1|6953186_6953618_+|GNAT-family-N-acetyltransferase
METTYKQYVISDDPSKIQVETVVEFLAGSYWANLRQPERIRASIRSSVCYGVYDGDRMVGFARVVTDGAAVYYVCDVFVLEAYRGQGISKKLVELITNAPEFEWMTGILGTRDAHGLYEQFGFQRDAQAYMKRLPQARRGEGE
>NC_017672.3|WP_014652392.1|6953659_6954142_+|hypothetical-protein
MFKKIVLTFAGLALFLVVVFVVWLQYGTRYNQIEVWQVNWAFETPPEQRTTTVFEHAGRDPDQYVIVEYSAEAVEELRGRNTWHSAGVPGAVQAHVASFQSLMKELHSQESQVLEEQFRNHPVPSHERLLYLTRTKEDGSRMLAVLDAENRRLYVMEVFF
>NC_017672.3|WP_013919822.1|6954117_6954996_-|MBL-fold-metallo-hydrolase
MQTIEKVGERFWYQTPVSETDRPILGMVVGRERRLMIDAGNSEAHARYFLEELEERGIGAPDLAVLTHWHWDHIFGLEWLHQHAVSIASSGTREAMEKLMPLSWSDEALDRRVEEGTEIEFCASAIKKEFPLHRDIRIALPVMTFENRMELDLGGITCVLQHVGGDHAGDSVVVYIPEEKILFLGDCIYADIFSAKRNYTPGKTLALLEVLETFDAETYVLSHWKPVSKAEFREEAALLRTMAQLTDEFAGDSARMREAYEKRKGRGLTEEELETLEYFVNGVALQKKTSMT
>NC_017672.3|WP_013919823.1|6955027_6955423_-|DUF5071-domain-containing-protein
MDHLREYLPKDKHDFESVAVLKGLEREKITELIPNLLEWLRDMNWPIAAEIARLLLRYPEEVIPHLWMVLRSGDEIWKYWCLEYLVGELPRIHFLVFKEELERIANQPTRGEELEEVHSAARRVLEFFGTN
>NC_017672.3|WP_013919824.1|6955446_6955635_-|hypothetical-protein
MFLIDLFPLMIGLYCVTLALWELREGHDRKRFVTLMFSGLVLVFVVPRLLGVGAGLFLTGFH
>NC_017672.3|WP_164923365.1|6955788_6955932_-|hypothetical-protein
MKEDGGHGMLFRTFGGEWMLTIHGPNRAPNERPVCYPVKELRASGLL
>NC_017672.3|WP_013919826.1|6956402_6957269_-|family-43-glycosylhydrolase
MLRRDEIRIRDPFVVPVQNEGLYYLYGTTDENVWQGPGVGFDVFRSRDLESWEGPFPAFRPEPGFWADRHFWAPEVHLYEGRYYMFASFKSEERSRGTQILASDSPLGPFVPLTGGPVTPAGWECLDGTLYLDEEGAPWMIFCREWLQVHDGEMYAVRLTRDLRGTEGEPLLLFRASEAPWTRHAREETDYVTDGPFLHRTESGELVMLWSSIGDKGYAIGLARSASGRIEGPWVHDADRLLEEDGGHGMLFRAFGGEWMLTIHAPNRTPNERPVFYPVKELRASGLQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_12

7000514-7000588

Orphan

Consensus_repeat	Method
AATAGCGAACCTCAGTTCCGCTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_12

>merge|NC_017672|12|7000514-7000588|CRISPRCasFinder
AATAGCGAACCTCAGTTCCGCTATCTCCTGAATAGGTCCTTCGAGCGGCAGAATAGCGAACCTCAGTTCCGCTAT

>NC_017672|12|10|7000514-7000588|CRISPRCasFinder
AATAGCGAACCTCAGTTCCGCTAT	CTCCTGAATAGGTCCTTCGAGCGGCAG
AATAGCGAACCTCAGTTCCGCTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014652401.1\|6993417_6994296_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014652416.1\|7013772_7014741_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NC_017672.3\|WP_014371816.1\|6996336_6996528_+\|YqaE/Pmp3-family-membrane-protein	unknown	unknown	gnl\|CDD\|376592
NC_017672.3\|WP_014371821.1\|7010789_7010981_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_014652402.1\|6994455_6994902_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_017672.3\|WP_014652407.1\|6997531_6997924_-\|immunity-22-family-protein	unknown	unknown	gnl\|CDD\|379476
NC_017672.3\|WP_128759052.1\|6995768_6996227_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372952
NC_017672.3\|WP_014652410.1\|6999218_7000178_-\|D-2-hydroxyacid-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|240646
NC_017672.3\|WP_014652414.1\|7006769_7010609_+\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350138
NC_017672.3\|WP_013919876.1\|7011392_7012175_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NC_017672.3\|WP_041618506.1\|6997957_6999001_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235906
NC_017672.3\|WP_014652406.1\|6996605_6997496_-\|aminoglycoside-6-adenylyltransferase	unknown	unknown	gnl\|CDD\|377357
NC_017672.3\|WP_014652403.1\|6994928_6995486_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
NC_017672.3\|WP_014371811.1\|6992529_6993231_-\|rhamnogalacturonan-acetylesterase	unknown	unknown	gnl\|CDD\|238859
NC_017672.3\|WP_016362917.1\|7012916_7013672_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_017672.3\|WP_013919877.1\|7012251_7012911_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NC_017672.3\|WP_014652417.1\|7014849_7015563_-\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|336781
NC_017672.3\|WP_014652413.1\|7003980_7006773_+\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350130
NC_017672.3\|WP_014652412.1\|7002606_7003692_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_017672.3\|WP_014652411.1\|7000682_7002398_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014652401.1\|6993417_6994296_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.63807e-27
NC_017672.3\|WP_014652416.1\|7013772_7014741_-\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	1.15151e-91
NC_017672.3\|WP_014371816.1\|6996336_6996528_+\|YqaE/Pmp3-family-membrane-protein	gnl\|CDD\|376592	pfam01679, Pmp3, Proteolipid membrane potential modulator. Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organisms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.	7.66444e-12
NC_017672.3\|WP_014652417.1\|7014849_7015563_-\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|336781	pfam07722, Peptidase_C26, Peptidase C26. These peptidases have gamma-glutamyl hydrolase activity; that is they catalyze the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates. They are structurally related to pfam00117, but contain extensions in four loops and at the C-terminus.	1.337e-78
NC_017672.3\|WP_014652402.1\|6994455_6994902_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.65187e-08
NC_017672.3\|WP_014652407.1\|6997531_6997924_-\|immunity-22-family-protein	gnl\|CDD\|379476	pfam14112, DUF4284, Immunity protein 22. A predicted immunity protein with an alpha+beta fold and conserved tryptophan,tyrosine and an acidic residues. Proteins containing this domain are present in bacterial polymorphic toxin systems as an immediate gene neighbor of the toxin gene, which usually contains toxin domains of the ColD/E5, Tox-REase-4, Ntox49 or Ntox14 families. The domain is also found in heterogeneous polyimmunity loci.	3.84298e-35
NC_017672.3\|WP_128759052.1\|6995768_6996227_+\|hypothetical-protein	gnl\|CDD\|372952	pfam14184, YrvL, Regulatory protein YrvL. YrvL prevents expression and activity of the YrvI sigma factor. It may function as an anti-sigma factor.	4.23647e-22
NC_017672.3\|WP_014652410.1\|6999218_7000178_-\|D-2-hydroxyacid-dehydrogenase-family-protein	gnl\|CDD\|240646	cd12169, PGDH_like_1, Putative D-3-Phosphoglycerate Dehydrogenases. Phosphoglycerate dehydrogenases (PGDHs) catalyze the initial step in the biosynthesis of L-serine from D-3-phosphoglycerate. PGDHs come in 3 distinct structural forms, with this first group being related to 2-hydroxy acid dehydrogenases, sharing structural similarity to formate and glycerate dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily, which also include groups such as L-alanine dehydrogenase and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. Many, not all, members of this family are dimeric.	0
NC_017672.3\|WP_014652414.1\|7006769_7010609_+\|family-43-glycosylhydrolase	gnl\|CDD\|350138	cd18817, GH43f_LbAraf43-like, Glycosyl hydrolase family 43 such as Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43. This glycosyl hydrolase family 43 (GH43) subgroup includes characterized enzymes with alpha-L-arabinofuranosidase (EC 3.2.1.55) activity. It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. Characterized enzymes belonging to this subgroup include Lactobacillus brevis (LbAraf43) and Weissella sp (WAraf43) which show activity with similar catalytic efficiency on 1,5-alpha-L-arabinooligosaccharides with a degree of polymerization (DP) of 2-3; size is limited by an extended loop at the entrance to the active site. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	3.84975e-168
NC_017672.3\|WP_013919876.1\|7011392_7012175_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.38609e-118
NC_017672.3\|WP_041618506.1\|6997957_6999001_-\|hypothetical-protein	gnl\|CDD\|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	2.33383e-05
NC_017672.3\|WP_014652406.1\|6996605_6997496_-\|aminoglycoside-6-adenylyltransferase	gnl\|CDD\|377357	pfam04439, Adenyl_transf, Streptomycin adenylyltransferase. Also known as Aminoglycoside 6- adenylyltransferase (EC:2.7.7.-), this protein confers resistance to aminoglycoside antibiotics.	3.62029e-166
NC_017672.3\|WP_014652403.1\|6994928_6995486_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	2.85533e-08
NC_017672.3\|WP_014371811.1\|6992529_6993231_-\|rhamnogalacturonan-acetylesterase	gnl\|CDD\|238859	cd01821, Rhamnogalacturan_acetylesterase_like, Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are highly branched regions in pectic polysaccharides, consisting of repeating -(1,2)-L-Rha-(1,4)-D-GalUA disaccharide units, with many rhamnose residues substituted by neutral oligosaccharides such as arabinans, galactans and arabinogalactans. Extracellular enzymes participating in the degradation of plant cell wall polymers, such as Rhamnogalacturonan acetylesterase, would typically be found in saprophytic and plant pathogenic fungi and bacteria.	6.31775e-89
NC_017672.3\|WP_016362917.1\|7012916_7013672_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.93739e-139
NC_017672.3\|WP_013919877.1\|7012251_7012911_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.00872e-68
NC_017672.3\|WP_014652413.1\|7003980_7006773_+\|family-43-glycosylhydrolase	gnl\|CDD\|350130	cd18618, GH43_Xsa43E-like, Glycosyl hydrolase family 43, including Butyrivibrio proteoclasticus arabinofuranosidase Xsa43E. This glycosyl hydrolase family 43 (GH43) subgroup belongs to the GH43_AXH-like subgroup which includes enzymes that have been characterized with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55), alpha-1,2-L-arabinofuranosidase 43A (arabinan-specific; EC 3.2.1.-), endo-alpha-L-arabinanase as well as arabinoxylan arabinofuranohydrolase (AXH) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. AXHs specifically hydrolyze the glycosidic bond between arabinofuranosyl substituents and xylopyranosyl backbone residues of arabinoxylan. This subgroup includes Cellvibrio japonicus arabinan-specific alpha-1,2-arabinofuranosidase, CjAbf43A, which confers its specificity by a surface cleft that is complementary to the helical backbone of the polysaccharide, and Butyrivibrio proteoclasticus GH43 enzyme Xsa43E, also an arabinofuranosidase, which has been shown to cleave arabinose side chains from short segments of xylan. Several of these enzymes also contain carbohydrate binding modules (CBMs) that bind cellulose or xylan. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	1.2374e-148
NC_017672.3\|WP_014652412.1\|7002606_7003692_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.55156e-50
NC_017672.3\|WP_014652411.1\|7000682_7002398_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0

>NC_017672.3|WP_014652410.1|6999218_7000178_-|D-2-hydroxyacid-dehydrogenase-family-protein
MKLRCAVLDDYQRAAASLADWSFLEDRVEVEFFHEHEDDEDKLAAALERFEIIVIMRERTPFRASLLERLPRLKLLVTTGMRNASVDLAAAAGQGVSVCGTRGNPEPTPELTWALVLGLARRLVPEHQALRSNGPWQSTLGIDLYGKRLGLLGLGTVGSRVARVGLAFGMEVAAWSPNLTAERAAEVGVQLAASKEELLESSDFVSVHLVLGDRSRGLLGREELKRMRPTAYLINTSRAPIVDREALVEALQEGWIAGAGVDVYDREPLPADDVFRTLPNVLTTPHLGYVTERNYRTFYGDAVEDIRAFLAGEPVRKLN
>NC_017672.3|WP_041618506.1|6997957_6999001_-|hypothetical-protein
MHRIWVIVLVGGIAAAAGLSLLGSAREELTPTPGSASPVLGTEARSPEHDEGPASKLGVVITQIAEKQTVVLDTAGGRPARETGGQSGPSEPAGPEQEAGPSEPAGPEQEALSSEPAAAGQEALSSEPAAAGQEALSSEPAAAGHEALPLLEPAAPGIAAGTVVGEGKADADGDGRTDTVRIRMTEGEERTDPNPGAFEGTHLHGTFEAVAETSDGRELGRFPLNEAFGGGEMIFRKGEPFRLLFDDYNDDGRPDFTVGQWGGSNGNFYVLLTIGPEGFQVLAKEIYSADHRESIRYRRTGKLAFRNIYYDQTRGAYMEVIRRWKDGAFAAEAPGETQDVGSAGVDP
>NC_017672.3|WP_014652407.1|6997531_6997924_-|immunity-22-family-protein
MDKDLTDESRVSLWLGSWSSEEAAQAYVEGSYTEDGDYVPSPFERDFAFRYDPDFIELNFKETPAADWESLLQGHSYDEEIIPAFMEEIGPLSRSFNTVILVYNLAYDAEHLRSGTAAGELEYIGQAAYD
>NC_017672.3|WP_014652406.1|6996605_6997496_-|aminoglycoside-6-adenylyltransferase
MRSEREMMDTILSFANEEEGIRAVIMNGSRVNPKAGRDPFQDYDIVFFVRQVGPFVRDRSWVRRFGGMMIMQTPDEMETEPDASGEYSRFAFLMQFADGNRIDLTLIPYERRDKLPGDSLSVLLLDKDGTLEPYPPPSDRDYLTQPPAPQSFAACCNEFWWVSTYVAKGLWRRELPYAKTMMEGPVRSMLVRMLEWHVGIHSGFTAATGKAGKHLEKHLAPKLWEAYVGTYADGDYDRIWEAMFVMGGLFRETAQDVASHFGYAYPEEDDRRVTAHLHYVRALPEDAEELYGEADG
>NC_017672.3|WP_014371816.1|6996336_6996528_+|YqaE/Pmp3-family-membrane-protein
MMYLLAILLPPVAVLLSGKPFQAFLNLILTLCFWLPGAIHACMVVHEKKQDRRMERLQRGLYK
>NC_017672.3|WP_128759052.1|6995768_6996227_+|hypothetical-protein
MSFKEKTLAASLFGLFLIVVLIFVFAAVFFLFTGTFHLLGIEYDSWRSVFVFIGAGLVSDLVLGFLLLFPKVLCTLYFARSPRWQLFLFLLLLQFTFDLISVHYIDEWMDGVTIGSGAEAAFVLIMLALDKLIPDRKKEKGKWAQGPPQGRF
>NC_017672.3|WP_014652403.1|6994928_6995486_-|DUF1700-domain-containing-protein
MSPERKQFLSLVSQHLSGLPEGERSEAVRKADRQIDHAVRSGLTEQAALIRLGDPKVIAEEYRGQARKSKRGTRSFKGVLRLIGFCCTTGLLTAIVVPFLAALAYGFGISSILIFAAGLLRTFGVPWIPLNLGPGLAIPAEYSMAATLIGGVVTGWIGYASGGVLKKYLAFLSASYRRVQPGQSC
>NC_017672.3|WP_014652402.1|6994455_6994902_+|GNAT-family-N-acetyltransferase
MSLLIRCAEPQDLLPLSGLMHDYIVGFYGNPWPGDDRIHNLIRSLLERQAGVQFVAEREGALIGFATLYFTYSTMKANPITIMNDFFLLEPYRGTEAQTRLFAHCRSFSLDNGFSYMSWITGTGNERAQHFFDEAGALRGSWVNYSIV
>NC_017672.3|WP_014652401.1|6993417_6994296_+|AraC-family-transcriptional-regulator
MNDVYSQKYTLENEAFAIQYMNYRGYFKMPRDHLHSYYEIFYLLEGERVYFINDTVYTAQKGDLVIVNPYDLHHTSSSDVPGFERMLINFTPEFALPLFAGSPPELLPFAQGSKLLRLPLKEQAAAEGLIRQMYSECAEAHPGYETCVKAALAQLLVRIHREFLRESRSPAPTEYTHPMHEKISEIAAYLTRHYAEELTLEGVAAQFFISPSYLSRVFKKITGYHFREYLLQIRVKEAQRRLRETRDKTISIAEQTGFRHISHFNTTFKKIVGLPPLQYRKQQQELHQKRLP
>NC_017672.3|WP_014371811.1|6992529_6993231_-|rhamnogalacturonan-acetylesterase
MREDRRVTVYIAGDSTAANYPEDKRPMSGWGEWIASYLAEEVRVSNRARNGRSSKSFIAEGHFDRIASSIGEGDYLLVQFGHNDEKPDEKRHTDPGSTYEEHLTRYIEMARSKGAHPLLLTSVERRKFNEVGELVPSHGDYPAAVQRLAEKLEVPLLDLCSRTQEAYRKLGAEASKAWFVWLEPGEHPNYPEGERDDTHFNELGAQKVAGLVAEALAASGSPLAGYLKAGAAG
>NC_017672.3|WP_014652411.1|7000682_7002398_-|ABC-transporter-ATP-binding-protein
MLRRFFSYYRPYRRLFLLDFGCAVVAGLLELGFPLAVNQFVDKLLPGQNWPLILWACAALLFIYVLNTALQYVVTYWGHMLGINIETDMRRKLFDHIQKLSFRFFDNNKTGHLMTRITNDLNEIGEIAHHGPEDIFIAVMTLLGAFGLMLTINWKLAVLTFVIIPLMAWFALHFSSRMTRTYERLFGDVGEFNTRVENNIGGIRVVQAFANEEYEKELFKVNNQQYRLTKLLAYKLMAKSMSITYMMMRLVSVFVMIAGTWFVIRGELSYGEFVGFLLLSNVFFRPIEKINAVIESYPKGIAGFKRYCAILDTEPDVADAPDAVAAGPLNGDIAFRSVSFGYDGSKQILNGLNLSIRAGETVAFVGPSGAGKTTICSLLPRFYECSEGSITIDGMDIRRMTLQSLRSQIGIVQQEVYLFEGTIRQNIAYGKLDAGDEEIWEAARQAQLEEFIRKQPDGMQTQIGERGVKLSGGQKQRLAIARMFLKNPPILILDEATSALDTATELAIQQSLAELSAGRTTLVIAHRLATIKNADRIIVVTEDGVAEEGAHQELVAAGGMYSRLHQAQFGT
>NC_017672.3|WP_014652412.1|7002606_7003692_-|GGDEF-domain-containing-protein
MPQDVFLNLSMNFLTMFVFFQLYFRYKVYVRSETVRHIILGVGFGLAQFLYRSFPIFIEGYREPIIIGGATFITAAVFGGGIAAFIAGCFPDLIGLAVRLLDQDARPFMPGFLVFIWVTVAVVVLAFRFLKWRRWQIWLLLNFVFYVLLHFLTPNSASTSFAVYRMAIELGCGALIYYFVSYMHQAHVTQKQLERYALTDGLTGISNVRFFQEVFPKLFSAAQRGKIGLSLLVTDIDFFKKINDTLGHPAGDQVLVEYAGLLRDNFRGTEIITRNGGEEFSVMFANVNREQALEASKRFHELVREHVFLEGHEKGPLRLTVSAGLAAYSAGVYSEPRELYAAADEQLYKAKREGRDRLYSV
>NC_017672.3|WP_014652413.1|7003980_7006773_+|family-43-glycosylhydrolase
MKKWASTLVLAVLLSSAGTPAANADNPVIKDVFTGDPAAFVHGDKVYLYTGHDEAAPNGNFFVMKDWLIFSSSDLVNWAREGSLDLSTFAWAQPNSAWASQLTERDGTFYWYVTVLNQDGTGYSIGVATSDNPISGFKDALGKPLVSSPMTQAPESMGTAPWDDIDPSVFIDDDGQAYLYWGNTHCYYAKLRPNMTELDGEIHRVTINNMEGTYTEAPWIHKHNGTYYLSFAHNYPEELAYATSSSPAGPWEYQGLLLDALTKDGSDPAASNTSHQSIIEFKGKSYLVYHNSALPTGGQYRRSVAIDRLHYNEDGTIRKVIPTSTGLDGMAHKLESYTNPAKYVRHLDGDVRLDPVDSSVFDSKWYIVPGLADSGAGYVSLQSVDRPGYYLRYSGSDASLGKHDGTPAFAESATFKVNPGLADASLSSFEAYSQPGHYLRHAGSQLKVEAVSGEAAEADATFRTAEADVRGLTLDQQSLLLQKGTQSVLTASVQPTSALNPKVIFTSSDPNVAAVGAPTVHLENGTVTVTVQAKSTGTATLTARTEEGRYTASADVTVEAAGTAGAITNVKIGVSAEAKKVTIEGQSTYGTGNEIAVRVRKPDGTVDFLDQTTSGDGGSFMFGIPLANPVKGEYQVSLGAADVSEPYTAKFEYTPAATGGNPGGGHSGSDSGGGSDSGSGNSSDDDEDSSSGSGAASGAGGVSAPAAGSGTASPGQSGGSAHGGSHASGPKPGSGKPAAPVFRDVQEGYSWAQEAIEALAAQGIIQGTSESTFEPGRPVSRADFITLLVRAFGLKGTPQSSSFADVQPGDYYYEAVSLARSLGLTDGVDGSRFDPQAEISRQDMMVLIARALKLTNKAELGGSPDGLKAFADAADVADYAAESTAALIQAGVIQGDGGALHPRSSATRAETAVMLHRIWNTFLKEGGPSQ
>NC_017672.3|WP_014652414.1|7006769_7010609_+|family-43-glycosylhydrolase
MRLAKPIVSCITALTLLAAPFTSLPLQRVSAASVDDGLLLRYAFDDGTDSRTVADSSGGGHTGELVGDATITATDKGGAVDLSGSGAYVRMPAGILDGLTDLTVSAWVYMDTAKPWASLYSFGNYRDSTNEAFSGLNFAPVNDASKSSLELFKTGFGSNQFLNLDPVPAKSWKHVTTVISGTRKTNSLYVDGVLQGTLTGMNALPGDIASTYNYIGYAQFPWEQGTGKGLDGRVSDFRLYGRALGWQEIRTLAGAQAEVVSVETAEVSTTAGVAPALPSTVNLRFGDGSTEPAAVTWDSIPAGAYATEGKFTVNGTAEGPPLPAAANVTVLAELQIVSAEPVEVITAAGSAPSLPSVVTAVYNNGTKSEVPVTWAEIDPSLYAEPDSRFTVKGSIAGTAAQAEAVVTVSGGIPEGLVTWYRFDALNGTTVPDASGHGRNATAVNGPLIMNVKEKTAIDFDSTKKQYVQLPAGIMSSLDDFTLATWIYIDSKTGDWTRIFDFGTGVSAGKMFLTTNLRYDMEGSIADATPSAPKVEQWTHVAVTKSGTVYTIYVNGKQAAVGTSTKKPSDYGETACNFIAKSNWTADPYLDGKLRDFRIYSKALPQQEVAGIVTSSYSDKEAVAAAKEVLTLGNTTQVVSDLELPVQGGNGVSITWTSDKPAVVSSTGKVTRPAKEEQDTAVTLTAELSRGEYKETRAFQVTVLADSIVSVDEVRVTTGRDFPPALPDNVTVRHYDGHTAEVPVTWERLPLEKLSAPGTFTLNGTVFSTALPAAAQISVAELVSIDEVKAETAAGQAPELPDTVNARYSDGTVKALPVTWSEVPVSAYDKPGTFAVQGSAATESYDNPLIERRADPHIMKHTDGYYYFTASVPEYDRIILRRAKSIQGLAEAEEVTVWQKHASGEMGAHIWAPEIHFIDGKWYIYFAAGTKEDIWKIRPYVLESADANPLTGTWTEKGMIGKPAGNTASFSDFSLDTTTFEHNGQRYLVWAQKENGPSNLYIAPMSNPWTISGDQVLISTPDYAWERQTYWVNEAPSVLKRGSKIFISFSASATDHSYALGLLTASDTADLLDPKSWTKSPEPVLVSSEEAGQYGPGHNSFTVGEDGTTDLLVYHARPYKKIEGDPLYDPNRHTRVKRLTWNADGTPNFGPLVSGRQLGPAAAVTAAVTVTRDAAYTAETVFSSERPGTGGKLEAAVTLTNRKQAAGQLVVVMVRYDSTGAMAESRYVTVDMTGKAQETAKLSLTFPAAAAGHKVKVFVWEGGSPDASNLKPAAPPAVFE
>NC_017672.3|WP_014371821.1|7010789_7010981_-|hypothetical-protein
MTVHDLRQRIQYMQYLGFDEAKKMWVYTYREKYKHRGVFGLVSGKEKVVVLPSLHGLNLKKAF
>NC_017672.3|WP_013919876.1|7011392_7012175_+|amino-acid-ABC-transporter-substrate-binding-protein
MKKRLAAIGLVLTAAFTILTGCSGDTGAAGGDKKLVVGIDDKFAPMGFRDEKNEIVGFDIDYAKAAAEKMGTEVEFQPIDWKTKESELNSGRIDLIWNGYTITEERKGKVLFTKPYLKNAQVVVTLAKSNLSKLDELEGKTVGLQSLSSAADALNASPVKSKIKTVTEYADNVLALSDLKIGRVDAVVIDEVVVKYYMAKEKDTFKLMSESLAPEEYGVGVKKGNEELLQKLQKALDELNQDGTAAKISQKWFGEDKVLK
>NC_017672.3|WP_013919877.1|7012251_7012911_+|amino-acid-ABC-transporter-permease
MSAGDYISMIKPMLEGAQMTVLLFLIAIAASIPLGFVLTLAVKSSIKPISWLAHSYIYVMRGTPLLLQLLFICFGLPMIPGIGEFLVLDRFAAACLGFILNYAAYFAEIFRGGLLAIDKGQYEASQVLGLSKWQTTTRIILPQMFRVALPSVSNESITLVKDTALLYAVAVPELLHYAQTVVNRDFTIVPFFFAGVIYLIMTLALTAFFKWLEQRFKFE
>NC_017672.3|WP_016362917.1|7012916_7013672_+|amino-acid-ABC-transporter-ATP-binding-protein
MAHVAIIEVSGLKKSYGTLDVLKRITFDVSKNDVVAVIGPSGSGKSTMLRSLVHLEEVNGGTIRVAGEDLVRDGVYSKPQEIKRITAKMGMVFQHFNLFPHLTVQENLELAPRLVKGESSEALRRRSSELLEKVGLTGRAAAYPAKLSGGQKQRVAIARALMMNPEILLFDEPTSALDPELTGEVLQVMKSLAEEHMTMIVVTHEMGFAREVAGRVLFMDNGEIIESGPPEQLFGSPQHERTKAFLGRSYQ
>NC_017672.3|WP_014652416.1|7013772_7014741_-|alpha/beta-hydrolase
MAKHVRLEPKAQKFAEDTAKPPYLFDLGPEKGRAKVDEVQSGEVTKLPVDIEERTIEGGPGGTVSVNILRPVNAPEQLPVIVYIHGAGWVFGNAHTHDRLIRELAVGAQAAVVFPNYSLSPEAKYPTAIEEVYAVVDWVAKNGRDLGLDPNRLAVGGDSVGGNMTAAVTLMAKERGGPAIRQQLLFYPVTDASFDTESYREFAEGYFLRRDAMQWFWDQYTESEAQRAEITASPLRATTEQLEGLPPALVITAEADVLRDEGEAYANKLREAGVRVTAARFQGTIHDFVMLNALADTAAARGAIALATAWLREGLGEKMGEQ
>NC_017672.3|WP_014652417.1|7014849_7015563_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MKKPMIGVLPLYDEEKESYWMLPGYMKGIEAAGGIPVMLPLTADPEVITAMAHTFDGFLFTGGHDVHPELYGERVEPVCGEPCRERDEMERMLFREVTAMDKPAFGICRGLQLFNALLGGTLYQDIPTQFGSDIQVNHQQQPPYDQPVHRVYIEKGDPLHEMLQTDSMEVNSYHHQGIKQLSSQLVAAAKAEDGMIEAVRMPDKKFVLAVQWHPEFSYTSDPYNFRLFEEFVSSCKS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_13

7096617-7096752

Orphan

Consensus_repeat	Method
AATAGCGGAACTCCGATGCCTTAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_017672_13

>merge|NC_017672|13|7096617-7096752|CRISPRCasFinder
AATAGCGGAACTCCGATGCCTTATTCGACTATTTCCCATCATTTCCCGAAGAATAGCGGAACTCCGATGCCTTATAAGGGGAAAATGGCCTGGAAACGGTGCTCCTCCCTACAATAGCGCATCTGAGTTCCTTTAT

>NC_017672|13|11|7096617-7096752|CRISPRCasFinder
AATAGCGGAACTCCGATGCCTTAT	TCGACTATTTCCCATCATTTCCCGAAG
AATAGCGGAACTCCGATGCCTTAT	AAGGGGAAAATGGCCTGGAAACGGTGCTCCTCCCTAC
AATAGCGCATCTGAGTTCCTTTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_041618508.1\|7087535_7090397_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366567
NC_017672.3\|WP_013919956.1\|7104283_7105273_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_017672.3\|WP_014371869.1\|7101467_7103096_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|381091
NC_017672.3\|WP_014371871.1\|7106967_7108083_-\|glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|226678
NC_017672.3\|WP_014371866.1\|7097929_7098565_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_017672.3\|WP_014371872.1\|7108167_7110444_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014652447.1\|7103224_7104247_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380660
NC_017672.3\|WP_013919942.1\|7083707_7084385_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380440
NC_017672.3\|WP_014371870.1\|7105285_7106776_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_017672.3\|WP_014371867.1\|7098649_7099666_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380661
NC_017672.3\|WP_013919947.1\|7092113_7093019_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_017672.3\|WP_014371861.1\|7084521_7085589_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380629
NC_017672.3\|WP_016362922.1\|7079730_7083381_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227785
NC_017672.3\|WP_014371862.1\|7086498_7087494_-\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350095
NC_017672.3\|WP_014371868.1\|7099662_7101471_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NC_017672.3\|WP_013919948.1\|7093033_7094005_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NC_017672.3\|WP_014652446.1\|7096945_7097758_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187632
NC_017672.3\|WP_013919944.1\|7085809_7086295_+\|heme-degrading-domain-containing-protein	unknown	unknown	gnl\|CDD\|179430
NC_017672.3\|WP_014371863.1\|7090486_7092067_-\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|270298
NC_017672.3\|WP_014371864.1\|7094451_7096047_-\|diguanylate-cyclase	unknown	unknown	gnl\|CDD\|143635

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_041618508.1\|7087535_7090397_-\|hypothetical-protein	gnl\|CDD\|366567	pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.	2.31081e-67
NC_017672.3\|WP_013919956.1\|7104283_7105273_-\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	3.58813e-81
NC_017672.3\|WP_014371869.1\|7101467_7103096_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|381091	cd17536, REC_YesN-like, phosphoacceptor receiver (REC) domain of YesN and related helix-turn-helix containing response regulators. This family is composed of uncharacterized response regulators that contain a REC domain and a AraC family helix-turn-helix (HTH) DNA-binding output domain, including Bacillus subtilis uncharacterized transcriptional regulatory protein YesN and Staphylococcus aureus uncharacterized response regulatory protein SAR0214. YesN is a member of the two-component regulatory system YesM/YesN and SAR0214 is a member of the probable two-component regulatory system SAR0215/SAR0214. Also included in this family is the AlgR-like group of LytTR/AlgR family response, which includes Pseudomonas aeruginosa positive alginate biosynthesis regulatory protein AlgR and Bacillus subtilis sensory transduction protein LytT, among others. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.25387e-50
NC_017672.3\|WP_014371871.1\|7106967_7108083_-\|glycosyl-hydrolase	gnl\|CDD\|226678	COG4225, COG4225, Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only].	1.5999e-84
NC_017672.3\|WP_014371866.1\|7097929_7098565_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	6.03315e-08
NC_017672.3\|WP_014371872.1\|7108167_7110444_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	9.887e-28
NC_017672.3\|WP_014652447.1\|7103224_7104247_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380660	cd20005, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate-binding protein such as CUT2. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	4.18563e-138
NC_017672.3\|WP_013919942.1\|7083707_7084385_+\|cupin-domain-containing-protein	gnl\|CDD\|380440	cd20306, cupin_OxDC-like, Oxalate decarboxylase (OxDC)-like cupin domain. This subfamily contains bacterial and eukaryotic cupin domains of proteins homologous to oxalate decarboxylase (OxDC; EC 4.1.1.2) such as MSMEG_2254, a putative OxDC from Mycobacterium smegmatis. OxDC is a manganese-dependent bicupin that catalyzes the conversion of oxalate to formate and carbon dioxide, utilizing dioxygen as a cofactor. It is evolutionarily related to oxalate oxidase (OxOx or germin; EC 1.2.3.4) which, in contrast, converts oxalate and dioxygen to carbon dioxide and hydrogen peroxide. OxDC is classified as a bicupin because it contains two cupin folds with each domain containing one manganese binding site, with four manganese binding residues (three histidines and one glutamate) conserved as well as a number of hydrophobic residues.	3.40685e-50
NC_017672.3\|WP_014371870.1\|7105285_7106776_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_017672.3\|WP_014371867.1\|7098649_7099666_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|380661	cd20006, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate-binding protein such as CUT2. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	6.61196e-110
NC_017672.3\|WP_013919947.1\|7092113_7093019_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.01609e-57
NC_017672.3\|WP_014371861.1\|7084521_7085589_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|380629	cd19974, PBP1_LacI-like, ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	2.51029e-91
NC_017672.3\|WP_016362922.1\|7079730_7083381_-\|hypothetical-protein	gnl\|CDD\|227785	COG5498, ACF2, Predicted glycosyl hydrolase [Cell envelope biogenesis, outer membrane].	1.25823e-51
NC_017672.3\|WP_014371862.1\|7086498_7087494_-\|family-43-glycosylhydrolase	gnl\|CDD\|350095	cd08981, GH43_Bt1873-like, Glycosyl hydrolase family 43 protein such as Bacteroides thetaiotaomicron BT_1873. This glycosyl hydrolase family 43 (GH43) subfamily includes Bacteroides thetaiotaomicron VPI-5482 endo-arabinase (Bt1873;BT_1873), as well as uncharacterized enzymes similar to those with beta-1,4-xylosidase (xylan 1,4-beta-xylosidase; EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanase and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the GH43 enzymes in this family may display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	5.12554e-147
NC_017672.3\|WP_014371868.1\|7099662_7101471_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.311e-70
NC_017672.3\|WP_013919948.1\|7093033_7094005_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	9.28749e-98
NC_017672.3\|WP_014652446.1\|7096945_7097758_-\|SDR-family-oxidoreductase	gnl\|CDD\|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.62135e-88
NC_017672.3\|WP_013919944.1\|7085809_7086295_+\|heme-degrading-domain-containing-protein	gnl\|CDD\|179430	PRK02487, PRK02487, heme-degrading domain-containing protein.	3.66253e-60
NC_017672.3\|WP_014371863.1\|7090486_7092067_-\|DUF3502-domain-containing-protein	gnl\|CDD\|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	1.04578e-28
NC_017672.3\|WP_014371864.1\|7094451_7096047_-\|diguanylate-cyclase	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.64795e-59

>NC_017672.3|WP_014371864.1|7094451_7096047_-|diguanylate-cyclase
MPGWIPKRLGLIKFQVLLTGLLAFSLAGTTAVLTGVALTKQNDSMTDSILQSNFEGARNLNVSMNKLLDLMMRELGAAAKFIGGQEGPLEQQAGYVNEMLGGRRFFAGAVLLDAKGVVRASTPGLLMQAGEALDEQVVEMALALPRPFVSGAFIAPNGHCAVLVSHPVMNRDGQRLGVVAGVIDLDERNVFSDFFEHASRSKNGTYAYLVNERGQVMLNPDDQRSGELIAPEVLRQTFPNEDIRYAAVRNTEGREVLAGYLTIPKIGWGIVFQSPAEVVDEALGVLIKAQLAWILPLFVLMLLVSLGIARKLAAPFAALTAAARQISAGERMVDPPFTRHWNYEAHHLAKAMMWAVGALQHQADRMSEQARTDGLTGLANRVCLEERVADMETGNQPYALLVLDIDHFKSVNDVYGHQTGDEALVHLARMISLEAGGESFAFRFGGEEFVVLLPGGGLEDGLDLAERIRSRMEHTVSPTGRPITVSIGAAACPRHGETFGEVFERADQALYQAKRSGRNRTAAAEELLPVG
>NC_017672.3|WP_013919948.1|7093033_7094005_-|sugar-ABC-transporter-permease
MNRAFAEPSVPSALTKQNQFTFWRKLRNNRTLLMMCLPAVLFFILFSYLPMPGLYLAFINYNYTDGIFGSEFIGLDNFRFLVESGDLWRLTFNTVAYNLAFILLGNALQIFVAIMLNELRSKFFKKVSQTLMFLPHFISAVLIGLIAYNILSFDYGLLNSILKSMGMEPVKTYSNPGIWPYIIILTYLWQSTGYGSIVYFAAIMGLDSEIVEAAEIDGANGFQRIRYIILPWLKPTFIILLLFSLGGVLRGNFGLFYNLVGANNTMLYSTTDIIETFVFRSLMNNFNFSMGSAVSLYQSLFGFAFVLTANWLVKKFSPDNSLF
>NC_017672.3|WP_013919947.1|7092113_7093019_-|carbohydrate-ABC-transporter-permease
MQASMNVRHTDRSSLIIRIVSYVFIALLAVSCLLPFVLIVATSLTSEASILKNGFNLWPKEFSTYAYRIVFENPELIIGSYIVTLGITLVGTAVGLFLVAMTGYALQRPDFHFRNKISFFIYFTTLFSGGIVPFYLLITQYLHLKDNYLAVLLPGLLSPFLIIMMKSFTQSIPHAITESAKIDGAGDFTIFMRLILPMSTPALATIGLFIALGYWNEWYNSMLFLSPDMKYRPLQLFLYNVVTSADFIRNSAAASNVPLRDVPLESMKMATAVVATGPVILFYPFVQRYFIQGITVGAVKG
>NC_017672.3|WP_014371863.1|7090486_7092067_-|DUF3502-domain-containing-protein
MVTRKIGMTLLSAVMAVSLTACSGGGNSESGKAAPGPAGTADSGQADTSKFETITYVMLGDKPKNGQVEKVLEKINVIMKEKINAKLELKWVEWADWQTKYNLLLASGEPVDLITTATDWLDAWPNAQKGAFLPLDQLLPKYAPETWKEIKPEEWDQTKYKDKIYMIPENSYTQWVNHGFFYRGDWAKEFGITEPIKDFETMGKYFQGIKDKKPDVIPWDSNGTNGEHAKGFIQSKTDAIELAVPTGYLPVVWGKSYDERYTAHSPIFDDTFVDFAKMMKAWADRGYWREDVLNYKGNVRDELKAGQTGADQHHTQTFSGLRTEMDAKQPGSELQMFAWSDTRGNLISQPITHGATAVGAKSKHPERALMAYELIRQNKEVYYLMNYGIEGVQYVIKDGKRAQPEGYDATRDGFSSNFWGGRVDRLEIPSATTWDGIKDIYKKYDGIKKPYPYGRFVLDKSKIDPQLTAMSQVTSQMGPAIAYGKAGDPVKAVEDLRSKLKAAGYDKVMAEVQRQLDEYKKLVESK
>NC_017672.3|WP_041618508.1|7087535_7090397_-|hypothetical-protein
MGTMNEMNTVNERNVTHEAGQKGSVDPNVRFERDAVYIGGTPVILLCSSLFYFRIPRGLWKDRLHKVREAGYNAIDVYFPWNHHEREPGVWDFGGERDVEAFLKLAAEEGLWVVARPGPYICSEWDGGALPAHLLTDRSMRLRDNDPNFLRATDRWFSRILPILSRFELGKDGTVIAVQLDNELDFYDCQDPSGYISALRDMALAYGVSVPLFACAGQGDLYRATGHAEGVMPTCNFYPNDREPAFEDKVVRYAQTLGGRGYPLCVTETNRSHFLLRRLLAGGAKLLGPYLQASGTDFGFTNAINNWGKPLAFLTSDYDFHGMITPGGAKREEFYEGRLLGGFLRSMGSSLAKAATVPSFFSVQTDLTVSAGMRYVLALDGGGYVIALPNVDGKDGSAALHGDGQVIPQYTSLRLAPDRCPLLLYEFPLQHWGLEGRLRYSTAEPAAVRSSEQKLILVLTAEKDAESEIALSVPDAAVVADGGAEVYRNEQELVLCYRPGAEGCTEIRLGDGSLLEIRLLERHRASRLLEILPGGELRFEEETAGEGEASESVAEAETLNWRKVTLPLGGAALPQRWLELGDQAVHLEEAGIYRGMAWYEAKRREPAKQPVVGVLLQDAGDILSVYTDGTYAGTVIPGGGHAYIPLDPPAVVSDLLIRAEIWGHTNFDDSILPGLRLNALKGLSRAVMVTRQVSPMSNWNFQTCSPKQAGEPLAAGELDPGFCSIQSWGGWMTTRLPESGIYWKTFTASADADRWVLHVPGAACVVRVYVNRQYAGEIVQSLPFVDLTPYIDRDGEIEIALYLERRDHQAAGRVMLYEGSDAVHWRVAGCQEEQLWQASEEAAGQAAACELPVPLLPGEWAWLQTELPAGLAAKCRKLRCEGRSMKITAFFNGHLVGRVWLEGAGVRPHMTGGGQDVIYLPEPWYREGSSRLSLLVEGAGDDAELRRVAFMPV
>NC_017672.3|WP_014371862.1|7086498_7087494_-|family-43-glycosylhydrolase
MNIYNEASDTAHPKQGLRLSDIPAHDPFVVADRESGTYYLYTGSGPQLHGMKRCGVVTYKSADLRHWEGPYVVFTVPDGVWANPRHGAWAPEVHAYKGSYYLLVTLHNNDRRLPDSPLIPMPNHWRGTAVAVSSSLEGPFELLQPDGPAVHSSLMTLDGTLYIDEEGRPWMVYCHEWIQMRDGTVEAVPLRADLSRAAGEPVHLFQASEASWDTAERTPGVEGSIYVTDGCQLYRTRGGHLVMLWSSYDQGQYVQTQARSVSGSLKGPWEQLEPLVRGDSGHGMLFRTFEGTWMLILHQPFPMPDSRCKLYEMEDAGDRFRVVAAREDLHG
>NC_017672.3|WP_013919944.1|7085809_7086295_+|heme-degrading-domain-containing-protein
MLELERKVKEMEEQERVFQFEEFTHETALELGLLLVQEAKRSGVRVTVDITRSGQRLFLHAMEGTTVGNEDWIRRKNNLTGRFGRSSWHTAMRLRLQGEELERDYGLPVKDYAAAGGSFPLHVKGEGILGTITVSGLPDQEDHDLVIGALQKYFDGLRQPE
>NC_017672.3|WP_014371861.1|7084521_7085589_-|LacI-family-transcriptional-regulator
MAKKVTMQQIADYMGVSKFVVSKALSGKGGVSEATKEKVIKAASQLGYFSKMNPYLPPKPAESTQDGGTKQSVLVLMPNVRFQTKESVYWGRILDGISARLEAAGLGMMIVMEQSADHFLQALNPSGILGLIGVGEISSSVLLEVHRLGVPFILVDHEDGLIPSDTVFVNNYDSMHRLTNYLIGIGHKHLLFVGDPRYSRSFYDRWTGFRSAVEEQGLAPDSPASLLIRLEGYEGFTTQIQEAVEALRRKALPTALVCANDTIALDTIEVLQRMGIKVPQEVSVTGFDNIERSYQTSPSLTTVNVPKELMGSRAVEKLLERVSKDQDATEKLLIAGEVMYRESSAGAAKTAEAEV
>NC_017672.3|WP_013919942.1|7083707_7084385_+|cupin-domain-containing-protein
MPMTPDPDFSSPSAQFFFDLSQDLYFRKDARNFINRLSVKDLNTLGGVSLLDIYLDTGNVVEPHIHQNASELVYVITGSAVISLINPFTNELLNYTAGPGQVVNIPQGWWHYEVASADGTHLLAIFDSKVPEAIFGSDILRLTPSGVWAHTYGLDQAQVAAAFAPITGTTIIGPPLPGQQTTKPMPYVPYGSPRQPVYAEQAAHYQRPAYPAPYLAQGYGWPYPY
>NC_017672.3|WP_016362922.1|7079730_7083381_-|hypothetical-protein
MKKHRMTLRGAKRSVLSTLALLTALSPLSLSHPQSARAAEPYLLSQNRTVYASSVEGANTPDLAVDGSTSSRWSSQWGADPQWIYTDLGAQAAISRVVIRWEGAFAKSYKIQVSNDESTWTDVYSTATGDGGVDEVTLSGSGRYVRVLGTERALSNYGYSILEFEVYGTGGVNPPPVNLGPNVALNRPVKVSSYEQSDYLPPGSTLPENGVDGSRQTRWSSNPTDNEYYQVDLGSQRTIGRIILDWEAAAGRAFDLQVSADGNQWTTIYREMKGQGGVQNIPVFATGRYVRMQGISRATSFGYSLFEFQVYDYVNGDPKPVYPITPLPAKSVVTEGSGSYLRNDITMPQPKYPLYKSDSLQKPLPSNDWWQSLFINKLGNGIITLPLKSKFQSQGLGVMTPGSGWITSDGKAVETGTNFDLTLMASNINTSSMSNRVVSYGDYSVDTVLSDSQTEDKMKVTFVKGSPYIYAQFSDPNSAEIYAPAVTRLFNDANAAVLAADGATLTADHIGIEVTNTDGAPNPAQVKRYYALNAPAGTVFKRIGPKIKITLPSGQNYLSLAALPSADKLNYFYQHGYAFVTDTKVGYTFNESTSAVETTFNTTTTLRRSGFPNTTLMTLAPHQWKIASTPLTDMTYPSIRGTLKVSEGNSFKTNDKFYGIVPQFTEPNDGGYSRQQLIQQLGILDQSTDTTEELMKADAYWQGKTLHPLAMGVLIADQIGDAAYKSKFLARLKTALTDWYTYTEGEPSYFLYYNDDWGTMYYKNSEFGANVGITDHHFTYGYFVFASAVLATYDKDFETRYGGMVEQLIRDYANPSRTDAQYPFFRSFDPYAGHSWAGGYADQDNGNNQEAAGESLFGWVGQYMWSILKGNKTYRDAAIWGFTTELKAVEQYWFNYDNDNWIPEYKHKSVGQIYGSSQFFGTFFNGNPVYVYGIHWLPTSEYLTSYGFDPAKAASLYQGFVTDNGGPETDWQHIVWPIQALSDPQAVLAKWNPAVLQQNEAFNTYYFVHALASLGHRTKDVWATGWSSATVYKKGTTYTAQVWNPTDAPVTVTFRNASGVTGTATVAPKSLVSVNPMTSSGGTQQPANVALNKTAAASSSEAGYAASQATDGNASTRWASEWNDAEWIYVDLGASYNVSRIKLNWEAAYAKGYKLQISDDPNSWTGKDVFVTAAGDGGVDDVNVTGRGRYVRLLGTARALPFGYSLFDFEVYGTQS
>NC_017672.3|WP_014652446.1|7096945_7097758_-|SDR-family-oxidoreductase
MKTILITGASSGIGRAAALYFQEQGWNVIATMRSPEKETELGRLDRVLVSRLDVVREETIQEALSQGIERFGTIDVLLNNAGYAAFGAFEAASEEQIHRQFDVNVFGVFRMTQAILPHFRTNQEGTIINVSSIGGRVAFPLLTLYHASKWALEGFSESLYYELAGLKIRVKVVEPGNVHTDFTGRSLDLIRSDSLEAYKDYTETVLQKQVESFQANGSSPELIARTIYRAASDGTDQFRYLAGEDAEFVMNMRRERPDAEFMSWIAGSFR
>NC_017672.3|WP_014371866.1|7097929_7098565_+|TetR/AcrR-family-transcriptional-regulator
MRKPGSVDQYIERIKPVVRKTRFSQLKIDEVAKVMDISKATLYKYFSSGEDIISTIVDHYTDYMLQADTLVQEDSVPYPERFQRLYGHSLRCVIYGSNLFMQDLQENYPPLYDKLAAAQQVRNKNLTPFYESGMEKKIFNPMNPILFMIQDEAVLRSIVEPLFCVQYDLTLKQALLDFYTLKKFQLLTPEHLQAVDDSIIENEIVQLLQSL
>NC_017672.3|WP_014371867.1|7098649_7099666_-|substrate-binding-domain-containing-protein
MNKGWGVVLAVLLLLAAGLGYYGWTSGADAKSRPILLIPKTTDPRISFWQAMRQGAEAAAREYGVEVQMAGMAAETEIEGQIRLLEEAILRKPRAIILAAADSNRLLPVCTRIKEAGIPLITVDSGLSAEAAASLIATDNYAAGRQVGDAMGALLKPGAKVAVISFVKGSTPAVERERGVRDSLEEKGITVAQTLYTNAEEELAYRLTTELLQTAAASELDGFIGLNEPSTVGAARALKEGQPEGGRVPMVGFDSSMREIAFLEEGVLQAIVVQKPFNMGYLAVKTAVEASSGVAAAPWVDTGAVTVTRSTMFSKANQKLLFPFGSEAYGGLVGESRE
>NC_017672.3|WP_014371868.1|7099662_7101471_-|sensor-histidine-kinase
MRGVRLFQYQSIHTQIALAFSALILCTTIILSYTAYRLSSDAVTGTSLEYTKELVRQVHTNVENYIYSMESIASLALSSGELKRYASLPRQDSEEGEELGRRLGDYFRSVLASRKDMASILFVGGHGGMVGGRSGESLKPSSEVRQQEWYLNAHQLEGGTAITSSHVQQLYRGEYPWVVSISKALPSTAAKPSGEGADGGVLLVDLNYSVIDNLCKQIQLGRRGYVFILAPSGDLVYHPQQQILNTQLKTERIPDILESRDGTMTFGRGAEQKIYTVSTTRFGWKVVGVVYPEDLARNKRAMQGSAALWGSLCLAVALSISVILSFRLTRPIKALEGHMKLAEKGDFGQRVEIESTNEIGKLARTFNVMIGRIQDLMEQIVQEQEQKRISELKALQAQIKPHFLYNTLDSIIWMAETRKVDEVVTMTSALAKLLRSSINQGEEWVPLAVELEQIRHYLTIQQIRYRRKFTYSIEVPEELYPYPIVKLVLQPIVENAIYHGIKHKAEPGHIRISGRRGAGGIELAVSDDGVGMTPEKLQTILGGTPRTKEAPGGSGVGVHNVHQRIALAFGPGYGLGFESELEEGTTVTIRLPELEDKGGSAG
>NC_017672.3|WP_014371869.1|7101467_7103096_-|helix-turn-helix-domain-containing-protein
MYSLMLVDDEDEVREGIMEKTDWVACGFRLAGAYENGRDAAEALEALRPDVLITDICMPFMDGLELSRYAAEISRDTKIVIITGYEEFDYAKEAIKLRVNEYLLKPINAREFMAFLGRLKTELDEQRASRENLSVIRQQLNQSLPLLKERFLERLSASVMKREELHRKLEYFGLTLPGPAFVSMVADIDPRQNPQAAGGAADAGSDLELLHFAVFNIFQEIFEKENGGAVFRTRDDRIGVLLCGLPESIGPLAQNLAAHAAYSVEKYLKLTLTIGIGRHCTALTQVPRSFREAGSALDYRLLLGSNRILCISDLEQGTSLHSMEYLEWEKKLLSALKMGKGSQVSSVLSAWLEEWRSAGLPVEKCYGMLYKFVVALMNWVAETGCGEAEVFGEDPFREMRALRTLDQLKQWLEGLCHRVICTLGERRSLATQSQMHLAEAYIKEHYVSESLSLQQVCDHIYMSASYFSACFKQHTGLTFVEYLTRLRIDKAKELLAATALKAYDIASRVGYPDPQYFSVIFKRHTGRTPKEFRLLAAAGETV
>NC_017672.3|WP_014652447.1|7103224_7104247_-|ABC-transporter-substrate-binding-protein
MAKKKSWFALAGVTVMAAALLGACGGNGGGSQQANAPASSEASKAGDSQAAGKVYIPVISKGFQHQFWQAVKQGAEKAAKEYQVEITFEGPESETQVDKQIEMLQAALGKKPQAVALAALDSKAVASLLQKAKAQNIPVVGFDSGVESDVPVTTAATDNKAAAALAADKMAELIGQEGEIALIVHDQTSRTGVDRRDGFVNRIKEKYPKIRIVDVQYGGGDHLKSTDLAKAILQAHPGVKGFFGANEGSAIGVLNAAAELKKEKLVIIGFDSGKQQIEAIRSGRMAGAITQDPIGIGYWSVKAAAMAVKGESVPKTIDTGFHWYDKSNMDSDTIKPLLYN
>NC_017672.3|WP_013919956.1|7104283_7105273_-|ABC-transporter-permease
MKVVSLNRQPSIRTGAMQKVLAFASLILLVVVFSLASSNFFRFDNLVAIILSTAVIGVLALGSTFVIITSGIDLSVGTVMTFASVMTGVIITTWQLPMPLGIIGGILTGAVCGLLSGLAVAKLKIPPFIATLAMMMITKGLSLVISGTKPIYFNDAPLFMDIAMGSVIGAVVPGFDIPNAVLIFFGLAVIASIILSKTIIGRFTFALGSNEEATRLSGVNVDKWKIIIYTITGAFSGIAGILMASRLNSAQPALGAGYELEAIAAVVIGGTSLSGGQGSILGTVIGALIMSVLTNGLRILSVPQEWQTVIVGLVVILAVYADMLRRRKK
>NC_017672.3|WP_014371870.1|7105285_7106776_-|sugar-ABC-transporter-ATP-binding-protein
MGEPLISMEGIVKRFPGVLALDGCRFELHAGEVHALVGENGAGKSTLMKILTGVYAKDEGRIRYEGREVEIPNTKAAQEMGISIIHQELNMMPHLTVAQNIFIGREPRRGWFLDEKALHRRTQELFARLHLQLDPGTPVSELTVAKQQMVEIAKALSFDSKVLIMDEPTAALTQSEIEELFRIIEQLRSQGVGIVYISHRMEELKRITDRITVMRDGCYIDTVRTESITIDQIIAMMVGRQIRHLSRPSAAENRNPVVLEVRDLSRGTQLRNISFHLRQGEILGFAGLMGAGRTEAARAIFGADPVDRGEIRIHGRPVSIKQPHDAVAQGLGYLSEDRKQFGLLTEMDVKTNIAVASYAGCARWGWMDDKRIAQTAERYVQSLKIKTPGTGQPVKFLSGGNQQKVVISKWLTRDCDILIFDEPTRGIDVGAKSEIYALLEQLAEEGKSIIMISSELPEILRLSHRILVMCEGRITGELSSGEATQERIMRLATMRT
>NC_017672.3|WP_014371871.1|7106967_7108083_-|glycosyl-hydrolase
MEYGLVDKMKAQYRAEPKWYSVRWHYIEGCILKAYLDSWAQTGSEEDYQFVKGFIDRLYDEEGNISAVNPAYYNIDQIRMATVLFPLYERERDPKYKRVMDLLYGQLSHYPRTNSGAFWHKSNYPHQVWLDGLYMGQPFYVQYTKQFAEPKEYSDTLAQFRNVRKNIYNEKKRLYSHAYDESRQMFWSDPVTGQSPNVWGRAVGWYVMALVDVLELLEGEEADAGFLQQDLQDTIDDMLRHQHSEGMWYQVVDRADHPDNYLESSGTLMMAYAILKGVRLGFLPGEYAGHGKKAFDGTVSRYVREEEGEVLLGGICRSAGLGTHPDTGAVRDGSVDYYLHSEKIVDNNGHGAAPLLMAYNEIKRLLNQAAS
>NC_017672.3|WP_014371872.1|7108167_7110444_-|helix-turn-helix-domain-containing-protein
MPRYLYRLLVFTLLLVAAPVVSIGMISYYIASKDTEQKVNEGNTHMLLQNQMRIEQVLKHVEMGAVQYVSSSLVTDHLYDDLTPDDFVTITDLAKGLYNLHSLSGVADTHLVNLEHDWMISNLGFTKVRDYLEPDLLSEYSSNPKNLFWLAGGTGKKRGGSTEEEAPARETVRMVVKLPMIAPSSEPKALLIIDMDEQKLESDMTPNEQWGNMYVVSREGLPFLTNPGSVDLTDSILLHLKTLTNSGGYFEADGMAVNYRVSPYNHWTYASVNSIESMTKESKKIAVITLNACLIIFVIIAAGAYYGSRRMYSPFRRLFLMMERYGGEAAVSRQQDEFAYIEDRFNSLFRTRKQLQTQLQGQRGQMREFFVLKLLMGQITESEFTYKSETYGFAGKGRSMGVLTLQIDALHETRFTENDKELLLFAINNMVGELIPSSGLLGNVLLDQSQISILISDSDDPDACKAFLHQTAAWIKTRVYELLQLKVSIGISRSFTRYTDANHAYTEALEALKRRISLGNDIILHYDDMKLGSGQRSSACVSLEHFEDDVIHALKVGDSVSTAGHYDRYVEAIMEKEIGFNDFQMVMLQLVNRVYRLVNEQEGSLHSLVRNQSILNRFVKLHTASEMTAWFKQEFLPPILEYMRERVDRQYINIAHEMVQLIHEQYGRDLTLETCAERLKYHPVYLSRVFKKEIGVTFIDYLTDYRMKMAKSWLENTDLKITEIAGRLNYTNATGFIRTFRKLTGMTPGQYRDSHSSG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_14

7133597-7133678

Orphan

Consensus_repeat	Method
TGATAGCGACCTTTATGCGAAGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_14

>merge|NC_017672|14|7133597-7133678|CRISPRCasFinder
TGATAGCGACCTTTATGCGAAGCATAACGGAGCGCAAAAAGATATAGCTGAGCGTTGTGATAGCGACCTTTATGCGAAGCAT

>NC_017672|14|12|7133597-7133678|CRISPRCasFinder
TGATAGCGACCTTTATGCGAAGCAT	AACGGAGCGCAAAAAGATATAGCTGAGCGTTG
TGATAGCGACCTTTATGCGAAGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014652468.1\|7148604_7149327_-\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NC_017672.3\|WP_013919973.1\|7124831_7126430_-\|FGGY-family-carbohydrate-kinase	unknown	unknown	gnl\|CDD\|198356
NC_017672.3\|WP_014652467.1\|7145975_7148255_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014652457.1\|7129518_7131882_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014652465.1\|7143010_7143931_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NC_017672.3\|WP_041618509.1\|7126662_7127652_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375122
NC_017672.3\|WP_014652466.1\|7144245_7145763_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270298
NC_017672.3\|WP_014652459.1\|7133832_7136940_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239491
NC_017672.3\|WP_051220090.1\|7127905_7129522_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270298
NC_017672.3\|WP_014652452.1\|7121464_7123099_-\|nickel-ABC-transporter,-nickel/metallophore-periplasmic-binding-protein	unknown	unknown	gnl\|CDD\|173854
NC_017672.3\|WP_014652458.1\|7132169_7133525_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|187711
NC_017672.3\|WP_014652463.1\|7140976_7141153_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013919970.1\|7120502_7121447_-\|nickel-ABC-transporter-permease-subunit-NikB	unknown	unknown	gnl\|CDD\|131836
NC_017672.3\|WP_013919969.1\|7119672_7120506_-\|nickel-ABC-transporter-permease-subunit-NikC	unknown	unknown	gnl\|CDD\|131837
NC_017672.3\|WP_014652464.1\|7142119_7142995_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_017672.3\|WP_014652453.1\|7123347_7124538_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NC_017672.3\|WP_014652451.1\|7118819_7119653_-\|nickel-import-ATP-binding-protein-NikD	unknown	unknown	gnl\|CDD\|223521
NC_017672.3\|WP_014652461.1\|7139375_7140080_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_017672.3\|WP_014652460.1\|7137051_7139376_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226957
NC_017672.3\|WP_013919982.1\|7141288_7141990_-\|RNA-polymerase-sporulation-sigma-factor-SigK	unknown	unknown	gnl\|CDD\|180266

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014652468.1\|7148604_7149327_-\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	2.57433e-36
NC_017672.3\|WP_013919973.1\|7124831_7126430_-\|FGGY-family-carbohydrate-kinase	gnl\|CDD\|198356	cd07778, FGGY_L-RBK_like, L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases. This subfamily is composed of a group of putative bacterial L-ribulokinases (RBK; EC 2.7.1.16) and similar proteins. L-RBK catalyzes the MgATP-dependent phosphorylation of a variety of sugar substrates. Members of this subfamily belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	0
NC_017672.3\|WP_014652467.1\|7145975_7148255_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.19932e-21
NC_017672.3\|WP_014652457.1\|7129518_7131882_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.71138e-27
NC_017672.3\|WP_014652465.1\|7143010_7143931_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	2.12225e-93
NC_017672.3\|WP_041618509.1\|7126662_7127652_-\|hypothetical-protein	gnl\|CDD\|375122	pfam17312, Helveticin_J, Bacteriocin helveticin-J. Bacteriocins are biologically active proteins or protein complexes that display a bactericidal mode of action towards closely related species. Bacteriocins produced by lactic acid bacteria are grouped into different classes. Class III of bacteriocins includes large heat liable proteins. Lactobacillus helveticus 481 produces a 37-kDa bacteriocin called helveticin J which is a representative for Clas III bacteriocins.	1.17973e-95
NC_017672.3\|WP_014652466.1\|7144245_7145763_-\|extracellular-solute-binding-protein	gnl\|CDD\|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	3.12532e-33
NC_017672.3\|WP_014652459.1\|7133832_7136940_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|239491	cd03397, PAP2_acid_phosphatase, PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains to be determined.	1.39163e-46
NC_017672.3\|WP_051220090.1\|7127905_7129522_-\|extracellular-solute-binding-protein	gnl\|CDD\|270298	cd13580, PBP2_AlgQ_like_1, Periplasmic-binding component of alginate-specific ABC uptake system-like; contains the type 2 periplasmic binding fold. This subgroup includes uncharacterized periplasmic-binding proteins that are closely related to high molecular weight (HMW) alginate bining proteins (AlgQ1 and AlgQ2) found in gram-negative soil bacteria. The HMW alginate uptake system is composed of a novel pit formed on the cell surface and a pit-dependent ATP-binding cassette (ABC) transporter in the inner membrane. The transportation of HMW alginate from the pit to the ABC transporter is mediated by periplasmic HMW alginate-binding proteins (AlgQ1 and AlgQ2). Alginate is an anionic polysaccharide that is made up of alpha-L-mannuronate and its 5'-epimer, alpha-L-guluronate. Alginate is present in the cell walls of brown seaweeds, where it forms a viscous gum by binding water. Alginate is also produced by two bacteria genera Pseudomonas and Azotobacter. AlgQ1 and AlgQ2 belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. However, unlike other bacterial periplasmic-binding proteins that deliver small solutes to ABC transporters, AlgQ1/2 can bind a macromolecule and may have specificity for either sugar or a certain type of polysaccharide.	3.79712e-80
NC_017672.3\|WP_014652452.1\|7121464_7123099_-\|nickel-ABC-transporter,-nickel/metallophore-periplasmic-binding-protein	gnl\|CDD\|173854	cd08489, PBP2_NikA, The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel transport system, which functions in the import of nickel and in the control of chemotactic response away from nickel. The ATP-binding cassette (ABC) type nickel transport system is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, the initial nickel receptor. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_017672.3\|WP_014652458.1\|7132169_7133525_+\|hypothetical-protein	gnl\|CDD\|187711	cd09615, Jacalin_EEP, Jacalin-like lectin domains of putative endonucleases/exonucleases/phosphatases and related proteins. Members of this taxonomically diverse family co-occur with metal-dependent endonucleases/exonucleases/phosphatases. They have not been functionally characterized.	1.41008e-44
NC_017672.3\|WP_013919970.1\|7120502_7121447_-\|nickel-ABC-transporter-permease-subunit-NikB	gnl\|CDD\|131836	TIGR02789, Nickel_transport_system_permease_protein_NikB, nickel ABC transporter, permease subunit NikB. This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds].	6.4482e-145
NC_017672.3\|WP_013919969.1\|7119672_7120506_-\|nickel-ABC-transporter-permease-subunit-NikC	gnl\|CDD\|131837	TIGR02790, Nickel_transport_system_permease_protein_nikC., nickel ABC transporter, permease subunit NikC. This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds].	1.47773e-127
NC_017672.3\|WP_014652464.1\|7142119_7142995_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.02338e-57
NC_017672.3\|WP_014652453.1\|7123347_7124538_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.22208e-40
NC_017672.3\|WP_014652451.1\|7118819_7119653_-\|nickel-import-ATP-binding-protein-NikD	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.66875e-129
NC_017672.3\|WP_014652461.1\|7139375_7140080_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	4.84006e-110
NC_017672.3\|WP_014652460.1\|7137051_7139376_-\|ABC-transporter-permease	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	6.7109e-11
NC_017672.3\|WP_013919982.1\|7141288_7141990_-\|RNA-polymerase-sporulation-sigma-factor-SigK	gnl\|CDD\|180266	PRK05803, PRK05803, RNA polymerase sporulation sigma factor SigK.	4.70944e-146

>NC_017672.3|WP_014652458.1|7132169_7133525_+|hypothetical-protein
MMPWRKVLPIALAASVMLPLGMTGGPVKPAHAAAGSFDVLSYNIGGLPAILSSSADPEKYTPLIGAKLAPYEVVNVQEDFNYHASLYASDTHPYRTPTSGGAGIGSGLNTLSNYPLYDLKRVTWNKRYGLFDNGSDELTPKGFTYTQVKLADGAYIDVYNLHADANTDTLSNEARRDNLTQLAAYIEANSKGHAVLVLGDTNCRYTRSEDQLKSLFVDKLGMKDAWVEKIRGGSYPAMGSAALLGTPGSTSPDNEVVDKIFYRSGAAVSLQANTYKVEDTYFTDSTGHQLSDHYAVSANFSFSTSGLIYSDLVGGDGGTPFNFLGSSAPAASQPASVTLRGASRLDAVSMSYANGSALTSGGTGGSASSLTLGSGEYFVSALLYQNTYNGTSRVFYLELTTNQGRKVSAGEKSGTATTLTAPAGSSIAGFFGRAGDTIDKLGLVYKALPAK
>NC_017672.3|WP_014652457.1|7129518_7131882_-|AraC-family-transcriptional-regulator
MIAMRKRNTVFANLAISYLTIVIVVVLLLCSIFYLVVPYNYNEEIRSRNGIMLKNAAQTMESAVLERVHKIYLDITLKKTTSVDIAPKGSLQGQNSTILDIQDHLKQEVITNSDLVQAIHLYYPKSGVMISSLYGLKTRVDADSEAFRSMDWIERMRTSGSGSLWTGPRMVPKDIHASASASNGMQPLMTYARSYPFHSTGEASDLMIGMDIKETAFSGILRQMMPADYPNTYLIDEQGIVISAADKTMLGRRAGETDSIKSMLASQAEAQSFTETIGDTPYVVSHHKLPSSPWKIYNVIQENSFYQKSLVLQKVILYICLFAILIGAVLSGVFTVISYSPIKRLMGKVKGLFEHPSETRHNEYVLIDTAIHKLSTKVSTLEETLQANQPVIKHNVVMNVLRNGYLPDELEDQLLSLNFSMDYSGYCCMVIDPVSRGFKELGSKANRYAVYKLINQLEAAGMEEARLIAEELPDHKIVVIVCAHHPDDALLESVSGQILSDVEAHFGLQFKIAWGLWVEEWSQVCQSFAAAQTLIKYGFFFPEASILRELSLLNREHSHLEIPQSALLKFKEKLQARSLNDVTAATDHLLEELMEGMYAADYGQFVLRNLVSMYADFLKTARVKQPGPLQIDLYRQYPSLYDIHSFREWLLSSIAECYELMEKRSDERAKDSIEAVKQYVISHLSEDLSLEAAAAEVFLSAKYLSRIFKEETGMGYTEFVTQKRMERALELMQNSSLTVEQVAGAVGYGTPAYFIKKFKEIHGCTPKTYVRSLVNTGSHSFDERSCL
>NC_017672.3|WP_051220090.1|7127905_7129522_-|extracellular-solute-binding-protein
MTMTISRRWGLILSALLLLLSACRTPAEQASVAEGASASAASAQGERYHITWTMHLNEAVPGDAEMVRFLEDKFNVDLEIWNLENNQYEALLDLKLAQGEIPDLFRIRQSYDLLKYRNQQVLAEIPPGMLEQHAPNLTRLIHTDAPGYMEYGQLDGRQYGIPVINPTNAYRVPVVYREDWLNQLGLKPPATLAELEKVMYAFTREDPDRNGKHDTYGLSSEGMNVVFGAFGQMVFTEQLYFAEKDHRLVIGALEPEMKEALGYLQKWYRDGVIDPEFVTGENKGGYKHLSHAFIHGRIGMTSMGNYYHWVQAGDYQVVDDKGGEVPVEAAFNALELARRNSQARIIFGQPVTGPRGKSGSKAYDKLMSYTAIGAGALQEPGKLAKILEILDYVSANPDLEASMTMKHGIQGKHWKWAGEAKDDVVILPPFDRSANYTNHIGANIGMMVPQRPRGRREKWASTLGLGEHGIYNALKVPLPSLIQYGPELIKLRNKAYVAMITGDTPIGAFDSFVKAFMEAGGEQVLSEANEWYRGQAPK
>NC_017672.3|WP_041618509.1|7126662_7127652_-|hypothetical-protein
MFHIPSWSLNPKQLKVLICALLTLLLFGMSGMPAQAAAPEKTVNASALLAYNLKGLKHNVAVQKAYIASKYVYVTQRSQGTCYLSRLLISGNDATYVDEMTITNTGHCQTLDMYTYNGINYFYFSSKADASTSYYWSLQVARLQYAPGVTVDYTDLHRFTYMNYANTTGTRLGETYRVDGGGNSTHTLFRVQTAEGTVTWSMYDTAALNKLLDSNEQVRMDSAAAVSASVGSFTQSGSGIVRPNGSFQGLDLLGNTELYTSGGAEGETPQIAMMTNTGVYKTLVRITNVGTHEIEGVQTKDGNVYFTIVTDPVNKQNTQKIYYVPDSIF
>NC_017672.3|WP_013919973.1|7124831_7126430_-|FGGY-family-carbohydrate-kinase
MSFDVKHAIESGKTVLGIELGSTRIKAVLIGEDHTAIASGSHDWENSYVNGIWTYSTEEIWKGIQDSYRKMAADVKQQYGVTLQTIGAIGFSGMMHGYMAFNQAGELLVPFRTWRNNITGPASETLTELFNYHIPQRWSIAHLYQAILNGEEHVAEIRFQTTLAGYIHWKLTGQKVLGVGEASGVFPIDIATKDYNAAMVNQFNELVASRNLPWKLEEILPQVLTAGESAGVLTAEGAKLLDATGELQAGIPLCPPEGDAGTGMVATNSVAKRTGNVSAGTSVFAMVVLEKELSKAYGEIDLVTTPTGNLVAMAHSNNCSSDLNAWVGLFEEFGKAMGLQTDMNKLYGTLYNLALQGDPDCGGLLAYGYLSGEHMTHFEEGRPLFVRSSDSNFNLANFMRVHLFTALGALKIGMDILLKEENVRLDEILGHGGLFKTKGVGQRIMAAALNTPVSVMETAGEGGAWGIALLASYMINKSENETLEAYLSQKVFAGEASETISPDPKDVEGFEVFMGRYKSGLAIERAAVEYLK
>NC_017672.3|WP_014652453.1|7123347_7124538_+|MFS-transporter
MVVQGPFSSVQIKLYLLAVLFFSANAVLTVILPLQSDAQGMGQGEIGLMMGSYMLTCMLFRPWAGQWLSRYGALAIMRILLLVHAVCLVLFAVTGTDSYLWLRALQGAVTAFFSMIMQLAMVTMLSAKDRAQGMSLYTLSTMIPQLFGPMAALFLWETGEPSLYLGVMIALSVTTWLTGFLAPLPAAPLGEGSYTFRDMLGSTAQLWRNRTLLVCSVVMLLASCMFGAVSTFLPLYMEKTGTGHAGYYLMLQGLVVVVCRFVLRKHIPSDGSWHTGLIAGLLLSAAAGSLLLSMMESLGALVYVSAVCNGLAVAFLYPTLVTYLSFVLPSRSRAVLLGLFISSYDLGFSSGGLFMGMLAQTISYSGMFTFCAWLGLSAFILVLMNKKRMSTSKAES
>NC_017672.3|WP_014652452.1|7121464_7123099_-|nickel-ABC-transporter,-nickel/metallophore-periplasmic-binding-protein
MFATKRKSLLLSMSLLLALSAAVAGCSTPKTETAGTAAETAAAGNKEETVTMAWPRDIGPMNPHLYNPSQLFAQSMIYEPLVAYKDGKIVPHLAESWTLSPDGKEYTFKLRSNVKFSDGTAFTAATVKKNFDAVLKNMKLHTWLGVISVLEKTEAVDDATFKMTLKEAYYPTLHDLAVVRPVRFLAESGFPDDGDTSKGVKNPIGTGPWMLSEYKKDENAVFTPNPNYWGEKPKVDKVVVKVVPDAETRVLAFEKGDLDLIFGEGVISFDAYKQLEQTGKYETKLSEPVGTRNLVLNTMNEKLADLRVRQALHQGFNKQAMVEGVTLGMEEKADNILPKNLPYANIDVKPVEYNVEQAKALLEEAGWKLSAGKTVREKDGKALELELLYDKADLTQKAMAETLQAEWAAIGVKLNITGVELTVYIQRRKANEFDMNFYSNFGAPYDPHSFMTGVVQKGFGLSDPLQALPMKAEIDQKIKEGMTTTDEKARTALFSSVLTTLQEQSSILPISYIKKLAVYQKDVSTVQFPSNRDEHPFYGIDTKE
>NC_017672.3|WP_013919970.1|7120502_7121447_-|nickel-ABC-transporter-permease-subunit-NikB
MAIYIGKRILSIIPIVLFASFLMFVMIKLGPVDPAEAYLAAAHIHPDDEVLAAKRHEFGLDQPLLVQYAQSVMKMCRLDFGTSYITNEPVWQEVVLKFPATIQLALCSILLAILVSVPIGFLSAIFKNGAVDYSSRVLSYIGACIPIFWLGYLLVYFFSVKLDWLPVEGRGTWQHLVLPSVTLALWLIAIYTRLLRTTVLEELQEAYVRYARTRGIKERVIMLKYVLRIAILPMITALGMNMGKLLTGAIIVEQVFSWPGFGRYFVQSIVNRDIPVIQCYVLLSVCIVVGCNLIVDLLQLYMDPRISRKGRADQ
>NC_017672.3|WP_013919969.1|7119672_7120506_-|nickel-ABC-transporter-permease-subunit-NikC
MIGGLRRGFKSQKAVAVCSIIIVLFFLVSVFAPWIAPHDPVHVNLAVKLQSPSWEYPLGTDQLGRCNLSRLLYGSRVSLGFASLIFICSLGLGLLVGTAAGYRGGWLDAVLMRFCEGVMAFPSLILVLGLVGILGPGLFQLVIALMMVQWVYYARMFRNLVVGLKDRNFITAARISGSSQWQIIRRHMIPNILPPILVIGTLEMGWAIMDISAMSFLGLGIQPPTPEWGAMVNEGKSFIRNHPQLMLYPGLLIVVVVATFNLLGEALSERYGVKRRF
>NC_017672.3|WP_014652451.1|7118819_7119653_-|nickel-import-ATP-binding-protein-NikD
MAEQTSPVLQVRDLKVTVKTEQGKLPLVHSIDFELMPGRVLGLVGESGSGKTVTSLALMQMLDRKASEVEGSIRLNGRELNGRKEEDMRRVRGKEMALIMQNPMNAFSPVYSIGTQFIETIRTHTGLSKKQAAELACSAMTDVNLPYPSELLRKYPFELSGGMLQRVMIALSVCLNPSLIIADEPTTALDVTNQLQVLRLLDRVRQDYGTAILLISHDLGVIAEMADDVAVMQQGRIVEQADVFELFDHPKHAYTQTLLAARPMLQISPEMTHCIWS
>NC_017672.3|WP_014652459.1|7133832_7136940_+|phosphatase-PAP2-family-protein
MKTLKTVSTALSLTLLLQTIPAHFASAEAIPSIPLAEPAASVSSSVYLPPAPAWGHFVDTYKTNQAANNTTTSNAAIGMLSQFLELWTPGSSWDNGTKLNSSVLDANIQKVVDIAAKRPPAEADMAYYDDRRKQSYGVIDGLGSLTDVYRTNAGATTTINDIPADATTKKYDDGGTDAGDPNSNFGRIVTLVKTLRGNYSSTNPAKNFYAYKRPFRWADTSIIVPSLVPAISKTPETDGGYPSGHTNASYLSAFAMAYAVPERYQELLTRASEMGSSRIASGMHSPMDVMGGRIMATALSAAILADPDNAAVKQAAYDEAHAKLLTQTGTAEDRFSDYAKNKAQFTERLTYGFSQIGDTSKPMTVPKGAEVLLETRLPYLDGPQRREVLATTGLPSGYPVLDDPEGWGRLNLFAAADGYGAFHQDVTVTMDAYQGGFHAADRWRNDISGTGRLTKAGSGTLKLQGGNTYSGGTQIIGGLLVGESPSAFGTGDVAVNEGSLAEQVSGSLTIGGNYTQAAGGTLELNVGGAQDLLEIKGAAQLNGKLRLNFTDAYVPGGVMTILTHAKDQRTGQFASVETNGLPSQYKANVSYLSDRIQVAVENTSSSSGSDSSSSSSPAAPAADPKPAEGTKPADGALPAAGDRHKMSVSVPAAVDENGKAAAALQASQLSDLLNKINSQAAEVMMAELKVEPSKQAKSVELSLTKEAIGKLADSKVKEVAIVTPFGMITLSKDVLERLENTAGDAIRIGMAPADTAKFADEAKSLIGTRPALQVTLHSGTSSIKSFGGSRIGIQIPYQAAQGEDTNALGVSEIDVNGKPSLLPQSAFSPRDGQASFLTDHPGTFAVSYNRVSFNDTSAHWAGSYVTYLAARGIASGSGDSTFAPDTSITRAEFVKLLAGIAHADGSGFTASAFTDVQAGDWHMPYVAWAAQQKLVEGDANGQFRPDARISREELCVMLNRFAGLTGYSLPSAAGDAGFTDQHLISPWAADAVSALYQAGFIAGKGNRQFDPQGPTTRAEAAKLLAVFLQGMVEQR
>NC_017672.3|WP_014652460.1|7137051_7139376_-|ABC-transporter-permease
MNLFKKLLRDIKQSIGQFLALVLVVTVGAFFYTGLVTLSNNLSAYTKDYFQVHHLSDLNVYYDHISKQDTAALGNIEGINKVEGRYTFTATQSFDDTKATLKIHSIPAGNIMNTPAIIEGSIPSGKDQLLLDSHYAREHQYKVGDQIKLSVNDKDMPFIISGLGENVEYAKKNETQDHKTSGFAYMAEAGVPRIAGSLYYNEVLIDAAEGVDVDQLGQPIEAQSKKLSYVSQISKERTFSYSQLQQTIHNNQLMSRVIPLVLFIIEAIILFLTMSRIIDSQRNQVGIMKALGVKNSSIMLHYMGFPVLVGIIGSILGCVAAASLFIPLIEASNAKAYSLPNIAFSLSSFSVIPPILFSSAFGMLSCYLSGIGILRERAAQAMRPKPPKKMKKLLIEQFPGIWRRLSYSHKLILRNIFLHKQKALASSVGVVVSTVLLITAFGTQTSLQRVADQIEEVNTYDLKVEYTREAELQKLRLPAGIESSYHQSALPVEFIKGDHHENATLIVTEKDNDLIHFFDENDNPTALEDSGVLVPKSYADHYQVGVGDAIRIRFTDPSFANKTVDMKVAQISNQYSNPSFYCTIAYLQSFGIDYQPTSLLVKAGGAADLTSVRQFFEQDKQVDTIHDKHDLKESAQYILKQNRFIFVLFIISAVILSFGAIYTISSINIYERNRELATLKVLGYPKSKINRLIFVENMILTTFAVIAALPISGYMYSIIVEALSSTHQQIPDQLSLLVILVSVILAFLLTTLSNLLLRRKVSRIHMIESLKSIE
>NC_017672.3|WP_014652461.1|7139375_7140080_-|ABC-transporter-ATP-binding-protein
MKKLIEFKNVTKEYNIGEVPIKALNGVDFIINEGEFVVVLGASGAGKSTILNILGGMDTATSGKVTVGSQDITGLNEKKLTAYRAEKVGFVFQFYNLIPNLNALENVEFAAEVCKNHLDAKEILTQVGLKNRMNNFPSQLSGGEQQRVAIARAVAKNPSLLLCDEPTGALDYVTGKSVLKLLQDLNRETKTCVVLVTHNAAIAPMADKIIRLKSGKIESVTVNELKQSVEGIEW
>NC_017672.3|WP_014652463.1|7140976_7141153_-|hypothetical-protein
MNRTQDLSKLIKLTGDRAKLDAKANGTYIVYKTEAGQFVKEYSNGEIVRMNEQDLPHE
>NC_017672.3|WP_013919982.1|7141288_7141990_-|RNA-polymerase-sporulation-sigma-factor-SigK
MPGFFTAVALFIKELMLLVSYVKNNAFPQPLAEDDEEKHLKLMAQGNQHSRNLLIEHNLRLVAHIVKKFDNTGEDLEDLISIGTIGLIKAIESFSPDKGTKLATFAARCIENEILMHLRSLKKTRKDVSLHDPIGTDKEGNEITLIDILGSEHDDVVEKVQLKIEKSKIYKNLDILDEREREVVVGRFGLEAGGEERTQREIAKELGISRSYVSRIEKRALMKLYHEFYKAKR
>NC_017672.3|WP_014652464.1|7142119_7142995_-|carbohydrate-ABC-transporter-permease
MPAKPQDASGWALSAAAYVFIGMFSLLCFIPFWLVYIGSFTAEHQIVKGFQLLPTEFSLDSYRFLLQGSQVYRSAMVSLVVTVTGTVGAVLLTSMFAYVTAHPRVKYRNVLAFYIYFTMLFAPGLVGYYLLISNWLDLRDSIWALILPHLFSAFNAFLMTSYFRTLPFELNEAATVDGAHELYIFFRIIWPISMPVIATITLFYALSCWNDWFNALMFIDDPTKHPLQMMLRRIVSTSQNLDYLNANVNISPAAAGVQLSTVCITIGPIIFLYPFLQRYFIKGMTIGAVKG
>NC_017672.3|WP_014652465.1|7143010_7143931_-|sugar-ABC-transporter-permease
MGVVRELRKNKWLYAMALPVVVYVFIFSYMPMSAHLLAFKQFIPVKGLWGSRWVGLDNLMFFFTGPDWLAVTLNTVYLNLLFIIAGTFFSLLIALMLNEIRLVWFKKAAQSLVILPHFISIIVVNLMVLNFFNGQDGMINRMLRDVGMETVDWFQTPSVWPLLLTVIFVWKGAGWGSIIYLATLTGFSEEYYESARIDGAKRWQQIWYITLPLLRPTIIVLTLLALGRIFYGDFGLIYGIIGDNSLLFKATDVIDTYTYRALRDVSNMNSYSNAAAVALFQSVMGFITILFFNGVVRRVDPDSKLF
>NC_017672.3|WP_014652466.1|7144245_7145763_-|extracellular-solute-binding-protein
MRRGRGARGLALTVALMLAGTIAACSSDEAGPSGKGGEEGASGKLNAVTLKIMFPGDPPANWSEVKGELENRLADSLNVKLNVVFIPWADVMQKRQVALSSAEDYDLIWDNNPVQSIAAGLYEPLDGLIEKYGPDIKSTRSPQLLEANKVNGKLYAVPLEVNFIRPWTFVIRKDIREKLGVPPIKSYDELVRFMYTVKEKVPGITPFIPNGSEHVGVRMAGMLDPGANLAPVLNYAGLYTKGNDAKVYNIFDDMDPMMMKNFEMNHKFYKDGIFPKDVLLLKNGEFSKGKAAVTTFFDFGVNLGTRTGLEKSVPGATAEAFSLYDPGMKLSSTYKAGNYIAVPVVSKNKERAIQFINALNQKDNYDLLAYGIKGKNWEDAGEGLYKPIKENPYTGIPFAWGWNPKLDRIDATMDEEVIKLNQWERDPNNFTADILSGFTFDPSPVSNEIAQLSSMSKELFEPVVLGVIEPNEGLAKFKEKAYGHVKKIQAEYQKQLDAYLAGKKK
>NC_017672.3|WP_014652467.1|7145975_7148255_-|helix-turn-helix-domain-containing-protein
MWSRIKPKKMYLTIFLYSCAAVSLLTLMFTWFLSGQFVRTALEEMDKSHEAKMKQVMKSSEFTLQQLRQFALRIYSDESIKLWLSMEKGAEAPLALSKAATSVREFMSSEPFIHAIYLINFDLDRIYTSDSSIYSTQDFYDPALLDYIQHQTTPYLQYVNHEVEGETYLALVVPSAGPRQSYQGYAAILFSKALLKEYMLQVSSEDQNKLYIEGKNGEYILGNADPALAQELSAVQVPEGAAGWRWESGGETWSIRSEQLPIEGWKVYHLSPLSLWQAKVAKIRLEIIGSSVLLLAALLLFLYWQSYRSLKPLSDLAAHVKSRLGQGDPVNQSPLAGNEMALLHSGFQSLVDRIEQLDLSMKSSQALVKDDFLRQWILSPRPSKPVREFIESRTPLLRAGWFRMAVIRLESYGRFTEQYDFASRKLLRFSMGNILSEVLANQGYAAETVDFGSDHIVAILASPASEGEWEQVIAAAEEARVQIRQWLKLEVQAAVSPRLDAEENLPQTYHQLYELTLLRFIHSGEDKVYTREDLERYERGRGSELDEALLKQVIHSVQLRNEKALEGYWDQLTHQMRELSYEECRLQLTHIIYTIMKSFKHHSVLHGMKSIHSFLDQFATLGEVQSWMYREMLKIMDSHRRKSGSNRKEEVAAEMIDYVRNHLHDPMLCVDDIAAHVSMSVNYARQIFKDQFGSSLSDFIAGQRIDYAAKLLTTTDWTVAEITEQSGFQTKSTFFAAFKRATGMTPNQYRIEKSSGASS
>NC_017672.3|WP_014652468.1|7148604_7149327_-|YitT-family-protein
MRKFANIVFGCMVTAIGLLFLKHTHAVTGGTAGLSLSLSYLMNLPFTALFLAINIPFFLFSALTMGRSFTVYSVGSVLILTLFTGLDSLLPAFEPSNLVGAVLGGMGIGLGVSILFANNSSLGGANILAFYLRRKYGWDPGLVNFAFDGMVVLISLSAVGVTKALYSIGSIALASLIISYFKSKINSEPVKEIKTYAIPGKEHSGGVTLAELQAADDELQPEQAPLAEVPLYTDGSEGLR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_15

7263177-7263590

Orphan

Consensus_repeat	Method
CGGCTGCGGCATGTCGTA	CRT

10 spacers

The CRISPR arrays of NC_017672_15

>merge|NC_017672|15|7263177-7263590|CRT
GGGCTCCGGCATGTTGTCGAATGACGGCAGCACACCCGCGTTCGGCTGCGGCATGTCGTACGCAGGCAGTGCACCCATATTCGGCTGCGGCATGTTGTCGTACGACGGCAGTACACCCATGTTTGGCTGCGGCATGTCGTACGCGGGCAGAGCCCCCACGTTCGGCTGCGTCATGTCGTACGCCGGCAGCATGCCTGCATTCGGCTGCGGCATGTCGTACGCGGGCAGAGCCCCCACGTTCGGCTGCGGCATGTCGTACGCAGGCAGCATGCCTGCATTCGGCTGCGGCATGTCGTACGCCGACAGCATGCCTGCGTTCGGCTGCGGCATGTCGAACGCCGGCAGCATGCCTGCATTCGGCTGCGGCATGTCGTACGCCGGCAGCACGCCTGCGTTCGGCTGCGGCAGGTTCTC

>NC_017672|15|3|7263177-7263590|CRT
GGGCTCCGGCATGTTGTC	GAATGACGGCAGCACACCCGCGTT
CGGCTGCGGCATGTCGTA	CGCAGGCAGTGCACCCATATT
CGGCTGCGGCATGTTGTC	GTACGACGGCAGTACACCCATGTT
TGGCTGCGGCATGTCGTA	CGCGGGCAGAGCCCCCACGTT
CGGCTGCGTCATGTCGTA	CGCCGGCAGCATGCCTGCATT
CGGCTGCGGCATGTCGTA	CGCGGGCAGAGCCCCCACGTT
CGGCTGCGGCATGTCGTA	CGCAGGCAGCATGCCTGCATT
CGGCTGCGGCATGTCGTA	CGCCGACAGCATGCCTGCGTT
CGGCTGCGGCATGTCGAA	CGCCGGCAGCATGCCTGCATT
CGGCTGCGGCATGTCGTA	CGCCGGCAGCACGCCTGCGTT
CGGCTGCGGCAGGTTCTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_013920087.1\|7261529_7262078_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_017672.3\|WP_014371945.1\|7268762_7269236_-\|ACT-domain-containing-protein	unknown	unknown	gnl\|CDD\|179848
NC_017672.3\|WP_014371940.1\|7258857_7259361_-\|crossover-junction-endodeoxyribonuclease-RuvC	unknown	unknown	gnl\|CDD\|234587
NC_017672.3\|WP_013920081.1\|7257030_7258035_-\|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl\|CDD\|234619
NC_017672.3\|WP_014371943.1\|7266382_7267348_-\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NC_017672.3\|WP_013920090.1\|7264627_7265311_-\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
NC_017672.3\|WP_014652516.1\|7267418_7268705_-\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NC_017672.3\|WP_013920084.1\|7259611_7260442_-\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|238038
NC_017672.3\|WP_041618760.1\|7270150_7270933_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NC_017672.3\|WP_013920099.1\|7274491_7275724_-\|NarK/NasA-family-nitrate-transporter	unknown	unknown	gnl\|CDD\|225133
NC_017672.3\|WP_128759053.1\|7254817_7256506_-\|SpoIID/LytB-domain-containing-protein	unknown	unknown	gnl\|CDD\|274252
NC_017672.3\|WP_013920082.1\|7258213_7258861_-\|Holliday-junction-branch-migration-protein-RuvA	unknown	unknown	gnl\|CDD\|234645
NC_017672.3\|WP_013920086.1\|7260684_7261395_-\|bypass-of-forespore-protein-C	unknown	unknown	gnl\|CDD\|370208
NC_017672.3\|WP_013920077.1\|7252125_7252455_-\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|235518
NC_017672.3\|WP_013920098.1\|7272298_7274428_-\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239155
NC_017672.3\|WP_014652518.1\|7269376_7269880_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|239519
NC_017672.3\|WP_013920091.1\|7265501_7266386_-\|prephenate-dehydratase	unknown	unknown	gnl\|CDD\|237013
NC_017672.3\|WP_014652520.1\|7271134_7272217_-\|anthranilate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223621
NC_017672.3\|WP_013920079.1\|7253689_7254748_-\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	unknown	unknown	gnl\|CDD\|234666
NC_017672.3\|WP_013920078.1\|7252501_7253638_-\|tRNA-guanosine(34)-transglycosylase-Tgt	unknown	unknown	gnl\|CDD\|234642

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_013920087.1\|7261529_7262078_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.58044e-41
NC_017672.3\|WP_014371945.1\|7268762_7269236_-\|ACT-domain-containing-protein	gnl\|CDD\|179848	PRK04435, PRK04435, ACT domain-containing protein.	1.61014e-74
NC_017672.3\|WP_014371940.1\|7258857_7259361_-\|crossover-junction-endodeoxyribonuclease-RuvC	gnl\|CDD\|234587	PRK00039, ruvC, Holliday junction resolvase; Reviewed.	4.27776e-89
NC_017672.3\|WP_013920081.1\|7257030_7258035_-\|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl\|CDD\|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0
NC_017672.3\|WP_014371943.1\|7266382_7267348_-\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	5.98295e-127
NC_017672.3\|WP_013920090.1\|7264627_7265311_-\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	3.9756e-57
NC_017672.3\|WP_014652516.1\|7267418_7268705_-\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_017672.3\|WP_013920084.1\|7259611_7260442_-\|HNH-endonuclease	gnl\|CDD\|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	3.2972e-12
NC_017672.3\|WP_041618760.1\|7270150_7270933_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.42468e-93
NC_017672.3\|WP_013920099.1\|7274491_7275724_-\|NarK/NasA-family-nitrate-transporter	gnl\|CDD\|225133	COG2223, NarK, Nitrate/nitrite transporter [Inorganic ion transport and metabolism].	6.87732e-106
NC_017672.3\|WP_128759053.1\|7254817_7256506_-\|SpoIID/LytB-domain-containing-protein	gnl\|CDD\|274252	TIGR02669, stage_II_sporulation_protein_D, SpoIID/LytB domain. This model describes a domain found typically in two or three proteins per genome in Cyanobacteria and Firmicutes, and sporadically in other genomes. One member is SpoIID of Bacillus subtilis. Another in B. subtilis is the C-terminal half of LytB, encoded immediately upstream of an amidase, the autolysin LytC, to which its N-terminus is homologous. Gene neighborhoods are not well conserved for members of this family, as many, such as SpoIID, are monocistronic. One early modelling-based study suggests a DNA-binding role for SpoIID, but the function of this domain is unknown. [Unknown function, General].	4.07303e-43
NC_017672.3\|WP_013920082.1\|7258213_7258861_-\|Holliday-junction-branch-migration-protein-RuvA	gnl\|CDD\|234645	PRK00116, ruvA, Holliday junction branch migration protein RuvA.	2.54081e-77
NC_017672.3\|WP_013920086.1\|7260684_7261395_-\|bypass-of-forespore-protein-C	gnl\|CDD\|370208	pfam08955, BofC_C, BofC C-terminal domain. The C-terminal domain of the bacterial protein 'bypass of forespore C' contains a three-stranded beta-sheet and three alpha-helices. Its exact function is, as yet, unknown.	1.23904e-32
NC_017672.3\|WP_013920077.1\|7252125_7252455_-\|preprotein-translocase-subunit-YajC	gnl\|CDD\|235518	PRK05585, yajC, preprotein translocase subunit YajC; Validated.	5.72087e-36
NC_017672.3\|WP_013920098.1\|7272298_7274428_-\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239155	cd02754, MopB_Nitrate-R-NapA-like, Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol oxidation via a membrane-anchored tetraheme cytochrome. Members of the MopB_Nitrate-R-NapA CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NC_017672.3\|WP_014652518.1\|7269376_7269880_+\|NUDIX-domain-containing-protein	gnl\|CDD\|239519	cd03427, MTH1, MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the incorporation of such oxygen radicals during replication. This is an important step in the repair mechanism in genomic and mitochondrial DNA. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for activity, and contain the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as a metal binding and catalytic site. MTH1 is predominantly localized in the cytoplasm and mitochondria. Structurally, this enzyme adopts a similar fold to MutT despite low sequence similarity outside the conserved nudix motif. The most distinctive structural difference between MutT and MTH1 is the presence of a beta-hairpin, which is absent in MutT. This results in a much deeper and narrower substrate binding pocket. Mechanistically, MTH1 contains dual specificity for nucleotides that contain 2-OH-adenine bases and those that contain 8-oxo-guanine bases.	2.60218e-15
NC_017672.3\|WP_013920091.1\|7265501_7266386_-\|prephenate-dehydratase	gnl\|CDD\|237013	PRK11898, PRK11898, prephenate dehydratase; Provisional.	1.15566e-117
NC_017672.3\|WP_014652520.1\|7271134_7272217_-\|anthranilate-phosphoribosyltransferase	gnl\|CDD\|223621	COG0547, TrpD, Anthranilate phosphoribosyltransferase [Amino acid transport and metabolism].	1.20068e-60
NC_017672.3\|WP_013920079.1\|7253689_7254748_-\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	gnl\|CDD\|234666	PRK00147, queA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional.	0
NC_017672.3\|WP_013920078.1\|7252501_7253638_-\|tRNA-guanosine(34)-transglycosylase-Tgt	gnl\|CDD\|234642	PRK00112, tgt, queuine tRNA-ribosyltransferase; Provisional.	0

>NC_017672.3|WP_013920087.1|7261529_7262078_+|signal-peptidase-I
MHPIVKEIWAWFRSLAAAFVLTLAIGMFVFQPTKVLGHSMDPTLHNEQRIYVSKLSHTFRREPDYGDIVIIDSRVERPRTLKDDVLEHPLLRLVLGNDDPNMYVKRVIGKPGDVIELKDSKVYRNGTALEEPYINGTMNIREERSWTVPVGHVFVMGDNRNNSRDSRDIGFIPFDHVLGIKF
>NC_017672.3|WP_013920086.1|7260684_7261395_-|bypass-of-forespore-protein-C
MILLNFWNQLKKQWKRKLRSQRRWLGLALILLAAGVFGAGAWVLGLRNLQGLAPERPADHAVFGRVIQQPKQQENEVRELVKGIDGQREAFVKKAYVCGEELQRIGLMSSSDILSYYKDHPALTVSMNPDGAVLFTEEVDDLSPQCKDNAYFGLDAKGNLSLFSGVPAGGGEENVIRTFFQLNIQYLESSLPRETVKQLYQGIRVRDLDDYNSVLSTLSDYAVEETEKVMQVQPGS
>NC_017672.3|WP_013920084.1|7259611_7260442_-|HNH-endonuclease
MDMGAHCLLHKTCSRCGKTKYYLQFPTKGLKRSKNGARKNICRTCTRRKSKGKLLPAPDTAVMGELTAVQQALPAEPAPAVQAAEPVPLSLQPPAEEPEPFRLAPPAAAAGSRSAEARGADRRQAGPQSGGPRRTVPPLKAPVRKKPGAGRLLRQDRDGLIRMKGRSKNGKRWVQDIDWALAVLLVEERAAIVLTPYMIRRLYSNDDFRLMILERDRFTCRYCGEYGDTIDHIVPRAKGGHTTPVNCVCSCYACNQSKADKDADEFIRGAQERQKV
>NC_017672.3|WP_014371940.1|7258857_7259361_-|crossover-junction-endodeoxyribonuclease-RuvC
MRVLGIDPGIAIVGFGFIDKQGHKLVPVQYGCIQTEAHTSDSLRLRQVYEATVQLIDKYKPDAIAIEKLFFSRNVTTAMIVSQARGVLMLAAEQKGLPISEYTPMQVKQAIVGYGKAEKKQVQEMVKLFLHLSAVPKPDDVADALAVAICHAHSSGLQQQLNGAYKR
>NC_017672.3|WP_013920082.1|7258213_7258861_-|Holliday-junction-branch-migration-protein-RuvA
MIDFLRGPVVYRDTEYVVLDVNGVGYRIFCANPFGVAPSKDGRDGGEVTMFIHYHVREDAHLLFGFTTREEQSLFRLLLDVSGIGPKVAIGVLAGGRPETIAGAIRQENLSFLTKLPGIGKKTAQRMVLDLKDKLGAITGGLDEGLFAPSEPLSAVPEGQGAWGEAKAALMALGYTEAEADRAGSAIKGKLKGGETADAVTKLALQALFQESMMR
>NC_017672.3|WP_013920081.1|7257030_7258035_-|Holliday-junction-branch-migration-DNA-helicase-RuvB
MDDRIISAHLMMEDQVAEFSLRPRYLAEYIGQAQAKENLKIYIEAAKMRREALDHVLLYGPPGLGKTTLSNIIANELGVNLRTTSGPAIERPGDLAAILTNLQENDVLFIDEIHRLHRTVEEVLYPAMEDYALDIIIGKGPSARSVRLDLPPFTLIGATTRVGLLSAPLRDRFGVVSRLEYYTVDELSYIVSRTADLLQVSIVGEAAREIGMRSRGTPRIANRLLKRVRDFAQVKGDGIITQEITQQALMSIQVDPLGLDEIDHKMLRAIILSFQGGPVGLDTIAASIGEESQTIEDVYEPYLLQIGFLQRTPRGRMITPSACKHLGLPMPSRS
>NC_017672.3|WP_128759053.1|7254817_7256506_-|SpoIID/LytB-domain-containing-protein
MAGGAGSGVRQRGAAYQAYLGPFATKEAAAAAAAKQPGAAVAGPHYASAGSYAGLAEAQAAAAQIAAAGFAADPALHGAGYAVFVGGAADAAALEALKAQVAAAVPGVTLTPVDASLGYAVLRRELAGTAAVDAAAFGGGAKLWAEPAGGAASGIKVDERYDRAYRGGIEVSVYNGKLAVVNELPFQEYLYSVLGSELGASWPAEALKAQAVAARTYALKQGMKYGIAHISDTTTDQAYKGVSVEFPTALEAVKATEGEVLTYGGSLIDPLYYSNAGGKTAESTEVWGNAVPYLKSASSPDEGAQNGKKTWYKIVTPSGRMGYIRSDYAQATGEKNPAGLPYYEGNTTGTNVRGAPYVDDTANPSLFTVDIGDRFVVIGEAVESNAYAWIRGPFDSAKLKEKLGSQVSGSITSLEVTSRGASGRATAVSVNGQPVKAAYPDSLRGLLGGLPSTRFEIEETGRYTIQGAEGTVRTRTPGSSPVYIAGGTAAPRKSDAEAPLFVMNGAGQVRAATDDAQFIFKGTGFGHGLGMSQWGAKGYAEQGLDYRAILRTYYTGAEITRP
>NC_017672.3|WP_013920079.1|7253689_7254748_-|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA
MQVDLFDYHLPEELIAQTPLADRTASRLLTLSKTSGETAHHTFEDLEQYLQAGDVLVLNNTRVIPARLFGVKADTGAKAEILLLKQLEGDRWEALVKPGKRLREGAVIHFGVETGADGASQGEPLLKATVEETGAQGARVLRFEYEGIFNELLDRLGHMPLPPYIKEQLPERERYQTVYAKHEGSAAAPTAGLHFTEAFLHRLEQKGIQLAYVTLHVGLGTFRPVSAETVDEHDMHEEYYEVPQETAELVTAAKREGRRVVAVGTTSARTLETAAAEDGSLQACSGSTGIFIYPGYRFKAVDALLTNFHLPKSTLMMLISALAGRENVLAAYREAVERKYRFFSFGDAMFIY
>NC_017672.3|WP_013920078.1|7252501_7253638_-|tRNA-guanosine(34)-transglycosylase-Tgt
MPAVTYEHIKTCKQSGARLGRVHTPHGVIETPAFMPVGTQATVKTMAPEELKAMDAHIILSNTYHLFLRPGHETVKAAGGLHKFMNWDRPILTDSGGFQVFSLSDMRKISEEGVEFRSHLNGDKLFLSPEKAMEIQNALGSDIMMAFDECPPYPAEHSYAKQSLERTTRWAERCLKAHSRPEDQALFAIVQGGMYEDLRKQSAAELTSLDFPGYAIGGLSVGEPKHLMYEVLDYTVPLLPEQKPRYLMGVGSPDALVEGSIRGIDMFDCVLPTRIARNGTIMTSAGRLVIRNAKFANDFGPLDPACSCYTCKNYSRAYIRHLIKADETFGIRLTTYHNLHFLLELMRGVRQAIREDRLLDFRDEFFAAYGIDENSKGF
>NC_017672.3|WP_013920077.1|7252125_7252455_-|preprotein-translocase-subunit-YajC
MWELAAANAPAEATGPMAYLVTYGPLVLMFVVLYFLLIRPQQKRQKARNMLLGNLKKGDKVVTIGGLHGTILELTDDTVILRVNDVTKLTFERSAINTVTASPSGDEKK
>NC_017672.3|WP_013920090.1|7264627_7265311_-|MgtC/SapB-family-protein
MLNTEMILRLAVALFLGLLIGIDRELRQKPLGMKTSTVIAVGSCLLTIVSIYAVDKFSIKGYTQMDPMRLAAQIVSGIGFIGAGAILRRSNDVITGLTTAAMVWASAALGIAAGAGFYQEAFAAVAMIMLAVNLFPVVVKLLGPKQLREKYVSVKVEALGCEELSELVAYMDREYGLKHLKIKDIEGDRQRVHFYVVAPANRSTTAIYYNIKRLKQVQHVEVEDVSS
>NC_017672.3|WP_013920091.1|7265501_7266386_-|prephenate-dehydratase
MKKVALLGPGTYTEESALHYLGREAFEFVNYKLIPDVFGATQQGQTDYSVIPIENTFEGSVSLHVDTLVHEVDLPIQAEWVYPISINLLRLYDGGEDGDDLERACSRIRKVYSHGVTMAQCQQFLRRYLPHVELEPVGSNGEAARLVREGEDASVAALAPLGAGELYRLQTLAAGVQDHQNNFTRFVLVGPEKPELRRGSRMKTTILVTLPEDYPGALHQVLSAFAWRRINLSKIESRPTKKKLGSYFFYIDIEESLDTVLLPAAFQEIEAIGCQVRIMGCYPVFAYDKEVKEG
>NC_017672.3|WP_014371943.1|7266382_7267348_-|homoserine-kinase
MKVRVRVPASTANLGPGFDSLGMALNLYAWIDMSLAERTSVRLIGEGMPGVPTDKSNLIYKVAQMVFDKAGVSHPELEIAMYSDIPLTRGLGSSAAAIVGALAGANALIGSPLSDDELFQIATELEGHPDNVGASLFGGLVVAFWDGERAEHIRVEPHEQLEVLVAIPHFQLSTEKARGVLPRQTTLERAVYNVGHSSVLVAALCTGRLDMIPRAMKDALHQPYRASLVPGLADILENAAEHGALGAALSGAGPTIFTLVDRTSPRKRELEGYLKETLGREGIECTALWLSPEPSGVTVRAVQPEEDLADWVKSLRSGVGA
>NC_017672.3|WP_014652516.1|7267418_7268705_-|homoserine-dehydrogenase
MKKINVGLLGLGTVGTGVVRIVENHQHDLTSQSGSPIEIVKILVQDKSKARNISVSPDLLTDNPWDVVENPEIDVLVEVMGGIELAKELILAGLERGKHIVTANKDLMALHGPEIMAKAAEKGCDVFYEAAVAGGIPIIRTLTDSFSSDRITKIMGIVNGTTNFILTKMSQEGADYAEVLKEAQALGYAEANPTSDVEGFDAARKMTILSTLGFRTEVALGDVAVKGISQISKEDIAYGKRLGYEVKLLGIAEREDEHISISVQPTMVKKSHPLASVNGVFNAVYVHGEAVGETMFYGAGAGELPTATSIVADLVAVVRNLNLGIVGRRGFVSYNEKKLKSDEQIASKNFILLHVEDKAGVLAQITQVFAEYGVSLESVLQHPNAVNPFAEIIIITHDANKAAMNQVLEQFEAMDVVQSIKSVYRVEG
>NC_017672.3|WP_014371945.1|7268762_7269236_-|ACT-domain-containing-protein
MPDKEATGLNLQGMERYYLVRQDILPEALIKTVQAKELLARGEVRTVHEAVEQVELSRSAFYKYKDGIFPLSKLDRERIVTVSIDLEHRSGILSKVLAMIAELEGNVLTIHQSIPLQGVANVVVSVETSVMNDTVTELLERLHRLDGVSRAVLVGQG
>NC_017672.3|WP_014652518.1|7269376_7269880_+|NUDIX-domain-containing-protein
MIRARMLATAVLFHDGDLLMMKRSPNRTLSPGMWAAVGGHLEPHEINDPEAAVLREIQEETGLLPEDLEELRLQYILIRLNEQEIRQQFIYTARTNRRDVNLTEEGELHWIPRAEVMNRSIPFIFRRVLQHYFDRGPHPHVWVGTAGYDSAGTATVHFTELVDPQQV
>NC_017672.3|WP_041618760.1|7270150_7270933_+|ABC-transporter-ATP-binding-protein
MQGIRYVREDRELLAGIDWEVRRGEHWALLGLNGSGKTTLLNMICGYLWPTKGSIEVLGETYGSVDLRDMRRSIGWVSSSLQEKLYASDRTEAVVLSGKYATIGLYDRPEEEDVQKALSLMDQLGCGHLAGRPYQTCSQGEKQKVLIARALMASPRLLILDEPCNGLDLFARENLLASVEALAAGPGAPTLLYVTHHTEEILPLFTHTLLLRRGEVFAAGPTAELLTAGPLSSFFERPVDVLTRSGRAWLAPSETGASAE
>NC_017672.3|WP_014652520.1|7271134_7272217_-|anthranilate-phosphoribosyltransferase
METLPEVIIMKQWIKIVGTGRLGSRHLTYDEAVAAAHAIARGESTDAQTAAFLMAMRMKGEADDEMMGFIDVFRKYSLPYRSFSHSLNCAGPYDGRLYFPVTIPVSLLLASVGFPQVLHGSESLPPKLGQSLKELLEGLGVRVELEAKEWEKNFLALGIGFIWTDLICPPFGRVRHVREQVGLRTFLNTVEKVINPVHSLNMVIGVNHKTAMDHLIHLLPKSGFETAYIVQGVEGSEDLPTYKNSSIRKVTPWGDESSTIDPATFGFSGEPLEKCTKERQLELLRRIIAGDDSADIRNEREHVIFNTGLRLYWFDKVASYEEGFGLARSLLQRKEAQKLLGKWQELSSRSAFPSRLQANG
>NC_017672.3|WP_013920098.1|7272298_7274428_-|molybdopterin-dependent-oxidoreductase
MSDFLRHFQKQQAVQPPREKTTKTECPYCSVQCTMNLHEEKSIKVSRYSVTPNKEDPVTDGRLCVKGLNAHSHAVDDRRLRYPMLRIGGTLSPITWEDALGRIRSEVTEIQRKYGKDAVGVYGGGSLTNEECYLLGKFARVALGTKHIDYNGRFCMSAAAGASNLTFGIDRGLTNPLSEVPLAKCIILAGTNIAECQPTIMQTFRKARQEGCKIIVIDPRETATCSIADIHLKVRPGYDAALANGMLKVLLEEGYVDRAFVEERTTGFAELEEHLKKVSLAEVAALCGIPPQLIVEAARIYGAAETGMIFTARGVEQHASGVANVRNFLNMVLLTGKIGKPGCGYGAVTGQANGQGGREHGQKADQLPGYRLIENEEHRAYIAKVWGVPEESLPRKGVSAYEMMESINRGEIKGLIILGSNPIVSNPNAALVEEALKKLDFLLVIDLFESETAKLAHMVLPGSSYLEDEGTMTQLEGRVLVRRAIRPLPGKARLDWKILCDIAEVLGKGEYFRYTKAEEIFQELRIASKGGKADYSGMTYERIEQSHGMFWPCPEEGHPGTPRMFENGFAHEDGRARLAPIEHQNPKEVATRKYPYLLTTGRVLQHYLSGVQTRNTSELNSKYPEPLLEIHPDTAGEIGLVNGGRAKVTSKRGTIRLKVKYSAKIRQDTVFVPFHWGGDQCVNRLTNPALDPVCRMPEFKVCAVSISPN
>NC_017672.3|WP_013920099.1|7274491_7275724_-|NarK/NasA-family-nitrate-transporter
MDVKNFRKAGHFPSLLSAFLYFDVSFMIWVLCGALSLYITKDFNLTDAQKATMVAIPTLGGSIFRIPMGILADRIGSRKAGMIGMGLTILPLMWGWLGGTSLSQVQALGFLLGIAGASFAVSLSLASRWYPPQYQGLAMGIAGAGNSGTALATFFGPQLAAKFGWHNVFGLAIIPLLLVFVAYFLMAKDAPNQPAPKKIRDYLAVLKNIDTWWFSIFYAITFGGFVGFSSYFSIFFYDVYGDQSIEGGLTRVQIGYLVTITVIAGSFFRPIGGYIADRIGGMKFMLVLYSVVCMCAFAVSTMPSSFMVMLALTSIMMACLGMGNGSIFQIVPQRFSKEIGVVTGIVGAAGGLGGFLLPNNVLGPLKQATGSHVTGFIVVASIVLVVTLVFYAVTRSWRKDWATADSGVNF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_16

7425561-7425635

Orphan

Consensus_repeat	Method
TAGAGGAACTCAGGTGCGCTATTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017672_16

>merge|NC_017672|16|7425561-7425635|CRISPRCasFinder
TAGAGGAACTCAGGTGCGCTATTTTGTTCGTGGAGAGGTACGCTTCCGAGATAGCGGAACTCAGGTGCGCTATTT

>NC_017672|16|13|7425561-7425635|CRISPRCasFinder
TAGAGGAACTCAGGTGCGCTATTT	TGTTCGTGGAGAGGTACGCTTCCGAGA
TAGCGGAACTCAGGTGCGCTATTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_013920229.1\|7414656_7415319_-\|thiaminase-II	unknown	unknown	gnl\|CDD\|381699
NC_017672.3\|WP_014652568.1\|7424897_7425374_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_017672.3\|WP_014652573.1\|7433000_7434125_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380649
NC_017672.3\|WP_013920253.1\|7439577_7440417_-\|5-dehydro-4-deoxy-D-glucuronate-isomerase	unknown	unknown	gnl\|CDD\|179169
NC_017672.3\|WP_016362959.1\|7423197_7424694_-\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NC_017672.3\|WP_014652566.1\|7421660_7423046_-\|HD-GYP-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NC_017672.3\|WP_013920245.1\|7430203_7431367_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226669
NC_017672.3\|WP_041618517.1\|7437377_7438442_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380624
NC_017672.3\|WP_014652571.1\|7428510_7429455_+\|glutaminase-A	unknown	unknown	gnl\|CDD\|274797
NC_017672.3\|WP_014652572.1\|7431370_7432900_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224053
NC_017672.3\|WP_013920242.1\|7427301_7428180_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014652574.1\|7434271_7435495_-\|response-regulator	unknown	unknown	gnl\|CDD\|381091
NC_017672.3\|WP_081668851.1\|7435501_7437388_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NC_017672.3\|WP_016362958.1\|7416190_7417759_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213192
NC_017672.3\|WP_013920234.1\|7418827_7419082_+\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013920236.1\|7420245_7421508_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341031
NC_017672.3\|WP_014652569.1\|7426479_7427094_+\|FMN-binding-negative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378988
NC_017672.3\|WP_014372020.1\|7417758_7418352_-\|thiamine-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|227065
NC_017672.3\|WP_013920235.1\|7419307_7420099_+\|phosphatidylserine-decarboxylase	unknown	unknown	gnl\|CDD\|179544
NC_017672.3\|WP_016362957.1\|7415405_7416200_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_013920229.1\|7414656_7415319_-\|thiaminase-II	gnl\|CDD\|381699	cd19364, TenA_C_BsTenA-like, TenA_C proteins similar to Bacillus subtilis TenA. This family of TenA proteins belongs to the TenA_C class as it has a conserved active site Cys residue; the double Glu residues identified in the active site of TenA_E from the archaeon Pyrococcus furiosus is conserved in this family. TenA_C proteins (EC 3.5.99.2) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway. This family includes Bacillus subtilis TenA which has been shown to be a thiaminase II, catalyzing the hydrolysis of thiamine into HMP and 5-(2-hydroxyethyl)-4-methylthiazole (THZ), within thiamine metabolism. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect.	7.52694e-111
NC_017672.3\|WP_014652568.1\|7424897_7425374_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.05475e-17
NC_017672.3\|WP_014652573.1\|7433000_7434125_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380649	cd19994, PBP1_ChvE, periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system. Periplasmic aldose-monosaccharides binding protein ChvE that belongs to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	2.63378e-167
NC_017672.3\|WP_013920253.1\|7439577_7440417_-\|5-dehydro-4-deoxy-D-glucuronate-isomerase	gnl\|CDD\|179169	PRK00924, PRK00924, 5-keto-4-deoxyuronate isomerase; Provisional.	0
NC_017672.3\|WP_016362959.1\|7423197_7424694_-\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	2.55499e-110
NC_017672.3\|WP_014652566.1\|7421660_7423046_-\|HD-GYP-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	1.73887e-71
NC_017672.3\|WP_013920245.1\|7430203_7431367_-\|sugar-ABC-transporter-permease	gnl\|CDD\|226669	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism].	2.88817e-155
NC_017672.3\|WP_041618517.1\|7437377_7438442_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380624	cd19969, PBP1_ABC_sugar_binding-like, monosaccharide ABC transporter substrate binding protein. Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems that share homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge. The substrate specificity of this group is not known, but it is predicted to be involved in the transport of sugar-containing molecules and chemotaxis.	1.21574e-117
NC_017672.3\|WP_014652571.1\|7428510_7429455_+\|glutaminase-A	gnl\|CDD\|274797	TIGR03814, Glutaminase_1, glutaminase A. This family describes the enzyme glutaminase, from a larger family that includes serine-dependent beta-lactamases and penicillin-binding proteins. Many bacteria have two isozymes. This model is based on selected known glutaminases and their homologs within prokaryotes, with the exclusion of highly-derived (long branch) and architecturally varied homologs, so as to achieve conservative assignments. A sharp drop in scores occurs below 250, and cutoffs are set accordingly. The enzyme converts glutamine to glutamate, with the release of ammonia. Members tend to be described as glutaminase A (glsA), where B (glsB) is unknown and may not be homologous (as in Rhizobium etli). Some species have two isozymes that may both be designated A (GlsA1 and GlsA2). [Energy metabolism, Amino acids and amines].	5.31595e-165
NC_017672.3\|WP_014652572.1\|7431370_7432900_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_017672.3\|WP_013920242.1\|7427301_7428180_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	9.63969e-27
NC_017672.3\|WP_014652574.1\|7434271_7435495_-\|response-regulator	gnl\|CDD\|381091	cd17536, REC_YesN-like, phosphoacceptor receiver (REC) domain of YesN and related helix-turn-helix containing response regulators. This family is composed of uncharacterized response regulators that contain a REC domain and a AraC family helix-turn-helix (HTH) DNA-binding output domain, including Bacillus subtilis uncharacterized transcriptional regulatory protein YesN and Staphylococcus aureus uncharacterized response regulatory protein SAR0214. YesN is a member of the two-component regulatory system YesM/YesN and SAR0214 is a member of the probable two-component regulatory system SAR0215/SAR0214. Also included in this family is the AlgR-like group of LytTR/AlgR family response, which includes Pseudomonas aeruginosa positive alginate biosynthesis regulatory protein AlgR and Bacillus subtilis sensory transduction protein LytT, among others. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.63381e-56
NC_017672.3\|WP_081668851.1\|7435501_7437388_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	8.87528e-79
NC_017672.3\|WP_016362958.1\|7416190_7417759_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	3.23267e-75
NC_017672.3\|WP_013920236.1\|7420245_7421508_+\|MFS-transporter	gnl\|CDD\|341031	cd17478, MFS_FsR, Fosmidomycin resistance protein of the Major Facilitator Superfamily of transporters. Fosmidomycin resistance protein (FsR) confers resistance against fosmidomycin. It shows sequence similarity with the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. This FsR family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.49874e-106
NC_017672.3\|WP_014652569.1\|7426479_7427094_+\|FMN-binding-negative-transcriptional-regulator	gnl\|CDD\|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	2.04893e-25
NC_017672.3\|WP_014372020.1\|7417758_7418352_-\|thiamine-ABC-transporter-permease	gnl\|CDD\|227065	COG4721, COG4721, ABC-type cobalt transport system, predicted permease component [Inorganic ion transport and metabolism].	1.00811e-39
NC_017672.3\|WP_013920235.1\|7419307_7420099_+\|phosphatidylserine-decarboxylase	gnl\|CDD\|179544	PRK03140, PRK03140, phosphatidylserine decarboxylase; Provisional.	4.87501e-101
NC_017672.3\|WP_016362957.1\|7415405_7416200_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.73123e-24

>NC_017672.3|WP_014652568.1|7424897_7425374_+|GNAT-family-N-acetyltransferase
MTLASSPIRIITAGRAELSAVVPLFDAYRRFYGQPSDPEGAERFLEGLMARGDSVILLARQEGSAEALGFTQLYPGYSSVSMKRLWTLNDLYVRPEARGRGVAALLLEAAEGLARESGAKGLQLETAPDNRTAQRLYERMGYVRDEEYLHYFRSTMEN
>NC_017672.3|WP_016362959.1|7423197_7424694_-|PLP-dependent-aminotransferase-family-protein
MHFHIPYHSNLERYPTKLLALYHALRDSIVEGVLERGTRLPSTRELASAYGLSRGTVNQVYEMLAAEGYVDCRTGSGTYVAFRRSTRTSGAGAAAARPEEAPAYPLSPLSRRLGPPPGEPVHGGGEAPSSRPGSGAFIDFHYFAPDLSGFPREEWNRCLHAAVRGEPAARLLDEPAQGWEPLREAIAQYLRRARGLAAEPGQIAITGGSVQAIALLAQLLIGPGEAAVVETPSYGGFRRAVRAAGGRCIDAPIDGEGIIPAAWDARVLFVTPTRQFPTGAVLSLERRQRLLEWADAKGAVIIEDDYDSEFRHRGKSLEPLRVLGGEERVVYVGSFTKSLLPPTRLGYAVLPPPLVEPFTRAQALFEPFPVNLLEQKALAAFMAGGAYERHLRRMKRSYGRKFHLLSELVKRELGSLVDWTESDAGLHLFGWWRGGEAEYRAFRSAGEAEGVRWSETEAELGGQRRFGLYLNFPHLTEEQIREGVRRMVRGGERSGQRS
>NC_017672.3|WP_014652566.1|7421660_7423046_-|HD-GYP-domain-containing-protein
MGNIASIALSPYRRFTWTLGLSVGFIGVLLSAVTLWACSTFVTRDTVELTTAAVVKHFAKVPQLAAIFPESSGEEGSTSPVGEPHTPHSQTPADLLQSYDRVLPLVRMHFDLYSILDANFYDTEGRIVFSYDKEAIGQEVDASLAGSLERAATNAQVVHQRLSGHILHLWMPVQREDGQVAGVVEVKRDISEQDRQIGWLEGILMTIIVLGMLGLFLTLHHVFRNSAGTIDRQNRELEAMVFRIERTYDESLQALSSALDSRDNETHGHSFRVTSYALRLGMEMNLTDRELGDLARGALLHDVGKIGVPDAILLKPAELTEEEWVVMKSHVEIGYRMLKHIAFLSPSLDVVRYHHERWDGGGYPHGLREEEIPLFARIFALCDSYDAMTSDRPYRKGWGYNEARAEIERCTGTQFCPEVVRAFLRIPKERWLEIEEASREGEPRELLGQMLEETMSMKGGR
>NC_017672.3|WP_013920236.1|7420245_7421508_+|MFS-transporter
MQLQTGAAAGPAAKPAPQPDVRPTLFRILFAISLVHLFNDTIQSVIPAILPIIKDSMQLSYMQAGIIVFALNMTASVMQPVVGLYSDRKPMPYMLPLGMGLTFFGVLGLALAPNYALVLVSVLLIGLGSAVFHPEGSRVAYMAGGSRRGLAQSIFQVGGNTGQSLASIMTALVFVPLGQFGAIWFTAVAGLAIVVQMYISRWYAGYLKAHPRPAKSAAARRIDPLRSRQIKFAVGMLIFLVFARSWYHAGITIYYPFYLMDKFTITLERAQLFIFLFTAAGVLSTFLGGPISDKIGRRNVIFFSMLGSAPLALVLPYANEFWTYVILLVNGFIILSSFSVTVVYAQELIPGKVGTVSGLITGLAFGLGALGAVALGGLIDVIKLRPVMELVSYLPLIGLLTFFLPRDRTLKEWSSESGNA
>NC_017672.3|WP_013920235.1|7419307_7420099_+|phosphatidylserine-decarboxylase
MKISFFRLLTELSSRKSVSQLTGAFAKSRASRSLIPRFAKTYGIPLEDAEKAVHEYVSLNDFFTRRLKSGLRPIDASPETMVSPVDALITGMGPIKEGSILNVKGQDYTIEELLNHSPRMINYKNGFYYVLYLSPTDYHRIHSPVDGTIIEKEHVPGKVYPVNDFGLKHMRRVLSRNERLITYVEHEGGEVAVVKVGALNVASIQYVAPLPDLLERGGELAYFEFGSTVVLLTETGTFESRSDLQVGSKVRMGEKLGSFKRRG
>NC_017672.3|WP_013920234.1|7418827_7419082_+|hypothetical-protein
MNETVTVPIESTPILLGLTAEMVSNCTYCTMISSDPGYRTPVSCTKLSGSCCPILVNLATCLTCGEYKNACGNGGASAEGTDAF
>NC_017672.3|WP_014372020.1|7417758_7418352_-|thiamine-ABC-transporter-permease
MSKGLKLTDILVTVVIAVVFAVIYRLWGDVYNVLKIPGLQLEQLGYGMWFIAGTVAFLILRKPGVAFLAEAAAASGEMIMGSQYGVEAFTYGLVQGLLAELVFAAAGYKRHTALIAGLAGAASGVGSIVYDYFKLYLAELQSWNLMLYIVFRLVGAFVITGPLAYVIVKALEKTGVTQLVRPASSLDYQALDRKKTL
>NC_017672.3|WP_016362958.1|7416190_7417759_-|ATP-binding-cassette-domain-containing-protein
MNAADTHTAHGSGGPSAQEQEPAVSVTGLRLKFPGSAPLLFDDLTLEVPRGQKVLLLGPSGCGKSTLLQVFSGLIPKSIEVPMKADALQLPGAWGYLFQDPDTQFCMPFVDEELAFVLENLQVPREEMGERIRLCLEQVGLRLPDLHTPIASLSGGMKQRLAIASLLALNPDVWFLDEPTSLLDPEGTGEVWETVKRVTEGRTVLIVEHKIEEIAGFVDRVVLFGHDARILADGPPQRVFREHRQELQEYGIWYPGVWEDYDRRPDLMPERGQSAARSAQVAQPLLRLEAFCGFHGREKKIEIPSADIFGDDWIAVVGPNGAGKSTLLQALMQLIPTQGRYNLGPHAVKGFDDVIGDASYVFQNPELQFVTHSVFDEVAWDFRQEGLPEAEVRTRSGEVLEWYGLAGHRELHPYQLSLGQKRRLSVVSATGKARRLLLLDEPTFGQDAANTFALLEKLEEWRRGGSAIVMVTHDPEIVARFATRVWEVRGGRLAADLPPEAYRKLQAAGEAAAGKEAEAPCR
>NC_017672.3|WP_016362957.1|7415405_7416200_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MPLTWTFRETWLHRANPAFKIGLSVLMFLAVLLTHNINVLLHVTWMHLLLFYTASGLPLRRLLLLSLPFVLMLVSSSTSMLFFGKGETTWLQWGLIHITEESFYRSLHIGLKTVNMAVLGLLFGLTTSPVRLFYSLMQQTRLPARYAYSFMAALRLLPMIVTEYQALQMALKVRGVKRARGIRGWTDSIQRHAIPLLAQSIRRAQRIAVAMEAKRFSSDAGRTYYYVIGWSASDLVLAAAALLIWTAGLLLGGHLPFLSVTDVR
>NC_017672.3|WP_013920229.1|7414656_7415319_-|thiaminase-II
MKFSQELREAADASWQASFNHPFVRGIGDGSLPLDAFRHYVLNDAYYLSQFARVQALGAAKANDLFTVNRMAVHAQGTYGAELSLHEKFAGLLGITEEERAAFEPAPTSYAYTSHMLRAAYAGGLGDIIAAILPCYWLYYEIGERLAGCTPEEPIYREWIAAYGGDWFRELVEEQIARLDELAETASSQDRERMKRHFVTSSRYEYMFWDMAYRKETWPV
>NC_017672.3|WP_014652569.1|7426479_7427094_+|FMN-binding-negative-transcriptional-regulator
MRRKEFSVEEQNEIDAFLNEMSYGYLATEGADGWPHLTPLNYAYYNGNIYFHGSRAGSKMKEIAQSDKVSFAVSKEYAIIPSYYSDPRQACPATAFFKSVHIRGIAEPVEDLDEKAGALSSMMEKLQPEGGYAPITAEDPEYRGELRGVSVVRITVSELTAKFKFGQNMSEERRAHIAESLAERGRPDDAETAELMRRFCPHHQ
>NC_017672.3|WP_013920242.1|7427301_7428180_-|AraC-family-transcriptional-regulator
MDQASLYHPRYLEEECHLRTVAYYSKQWNGFQMPFHTHRAAEIMYVISGECTVEFAEDRVHLGKGDFILIDALVAHRLFVEESTVCRMLNVEFVLGPRQGAFPSFRQLAEENEVLRAMLGRVRPYLVLSDTTDVYHTLKSLVLELSDRSRGGFMVQLLLSQLLLRVARLAAEAEEHQANPGDLYVKKVIAYLHHHYDCDLRVKELAEAVNLHPSYLHRIFRLHTGSSIVEYLTALRIEKAKMLLAQTDIPVIEIPGYIGMNSRQYFSAVFKKQTGLTPLQYRLGIEAWQRDE
>NC_017672.3|WP_014652571.1|7428510_7429455_+|glutaminase-A
MNPKNDLDLIADKLPEWLEESRKYTVLGRPASYIPELAYAPAEALGVTVMGADGTDITAGDCGLTFTMQSISKVFTLLLALMDHGEDGVFQKVGMEPTGDDFNSMLKLELVPPGIPFNPLINAGAIAISSLIHGVSPSDKLSRILAFFREVSGDPDLTYNEAVYASESAHAHRNRSLAYFLKDNHVLDGDVEEVLDLYFKHCSIEVTCRHLARMALVLALNGKDPVSGRELIPKRYVAIAKTFMITCGMYNASGEFAIKVGMPAKSGVAGGILALVPGRFGVGVIGPALNHKGNSTAGVHLLQTMSEAMDWSIF
>NC_017672.3|WP_013920245.1|7430203_7431367_-|sugar-ABC-transporter-permease
MNTVKELFRGNIRQYGMVIALLFIMVFFQILTDGILLKPLNITNLILQNSYILVLAIGMLLVIITGHIDLSVGSVAAFVGAISAILMVDMQMHFVPAMLISLLIGALVGAWQGFWVAYVRIPSFIVTLAGMLLFRGLTMIVLDGKSIAPFPKTFQKISSGFLPDAFGGKIHMLTIIIGIVLSLILVFSEWRKRSTQQKYGFEVGSGALFALKLAAMVAVLNIFTYVLATYEGIPNILILLFVLIVIYTFVMNRTIVGRHIYALGGNEKAAKLSGVKTQRITFWVFVNMGVLSALSGLIFAARLNSATPKAGVNFELDAIAACFIGGASASGGIGTVIGAIVGGLVMGVMNNGMSLVGLGIDWQQGIKGLVLLLAVGFDIYNKNKGVS
>NC_017672.3|WP_014652572.1|7431370_7432900_-|ATP-binding-cassette-domain-containing-protein
MTDIILEMKNITKEFPGVKALERVNLQVKEGEIHALMGENGAGKSTLMKVLSGVYPHGTYTGDILFKGQVCEFKDIKMSENLGIVIIHQELALIPYLSIAENIFLGNERAKGGVVDWNETFVRTKELLDKVGLHESPNTQIAQLGVGKQQLVEIAKALAKRVQLLILDEPTAALNEDDSENLLQLLLELKRQGISSILISHKLNEISKVADSITILRDGRTIETLDMRRDNITEDRIIKGMVGRDLTQRYPEREPKIGETIFEIKNWNVFHPQQADRQVLHNINLGIRRGEIVGIAGLMGAGRTELAMSIFGRSYGQKISGTMIKDGRPLELRSIPEAIDSGIAYVTEDRKHYGLVLMDNIKQNITLANLGKISKRGVVDENREVVEAESYRKKMNIKSPSILQKTGNLSGGNQQKVVLSKWMFAEPDLLILDEPTRGIDVGAKYEIYTIIHQLAAEGKGVLIISSELPEVLGMCDRIYVMSEGRITGEFPRAEASQEKLMKFMTKTRG
>NC_017672.3|WP_014652573.1|7433000_7434125_-|sugar-ABC-transporter-substrate-binding-protein
MKKAVSMMMLLVLLFSLAACGGGGGAAETTGGAAQTEGGSSGDGKAGKVGISMPTKSSERWVSDGANMVKEFEKLGYQTDLQYAEDVVENQVSQIENMITKGVKVLVVAAVDGESLTDALDKANAAGIKVIAYDRLIKKSEHVAYYATFDNFKVGVQQASYIEKKLGLKEGKGPFNIELFAGSPDDNNAYFFFDGAMSILKPYIDSGKLVVRSKQTEMKQVATLRWDGAAAQARMDNLLSANYATEKVDAVLSPYDGISIGILSSLKGVGYGSGSKPLPVITGQDAELASVKSIIAGEQTQTVFKDTRELAKKAVAMADAVLKGKEAEVNDTKTYNNGVKVVPSFLLEPVSVDVTNYEQVLVGSGYYTKDQLAK
>NC_017672.3|WP_014652574.1|7434271_7435495_-|response-regulator
MEKRWKVLIADDEPWIREGIRDAVDWTSLGMEVVAEAEDGEEALELALEHSAEVLLVDLNMPIMNGIELMKRVREELPGSRIVVITGHDEFVFAQEAIRLEVDDYILKPADPKQLHTVLGNVRRKLELAEKQNGYLAMASKQISKNFPLLRERFCLEWVEGTMTEGEILEQLQFLELPASAPQRLGIIRWPESSAPQRLMKESDRQLLLFAIENIAAELLEPYRHAMFRDTMGLLVVCLWEAVPESVYAEIERAVQTYLKLTVHLCFEHVEGSVTEIASVYRHCRTKVYEEQQISPIVRRARQYIRDRFTDSGLTLESAAAELQMSPVYLSRVLKQELGMPFVSLVTQMRIQLAVQLLGGTDLPVGEIAERTGYESQHYFSTAFKKVMGVSPNQYRRGVVYTEGRIE
>NC_017672.3|WP_081668851.1|7435501_7437388_-|sensor-histidine-kinase
MRNNRLQRILAAVRPQTKTGRYRMNDLPIRDKLIIHFLLIIILPSVLLGGSILWTVDRIIEKQVSENTLQLIGKVNKTLESYAGNMQNITYFLSFQPEVKRFLERGPGTAQRGAAAEEYEIRQFMQGFTTLYPEVAGVLVVNAQGDYISNEMYARSSRSLTEEEWYKQAVASKGIFTMVGHPQGRNVTTHVSYKDSEVVSAVRAILDPQTQAVKGVVLIDLKLRVIAETAKDVRLGKSGYLTIIDGRGDVIYAPPRPLVSRIPAEWLGDHGSGTFAQEVGGEKLQFIYRASPFTNWTTVGVFSMEESALEAQEIGFYVVCFVFIVCLFGIAASYYLSHSISRPIVQLMSFMRIAESGDLTVRYWGDRRDEVGNLGRSFNTMIAQIDKLLTLTERQERQKREAELRSLQAHIKPHFLYNTLDTIHWMARKKGAEDVAEVVQSLSRLFRIGLSKGSDRIMLAHEIEHICSYLTIQKSRYKDKLNYTIDVPEHLMNVSVLKIVLQPIVENAIYHGIKERRGPGHISVEAEERWGMLLLRVRDDGAGMDAEKLRELQERLAAAAASEDEQGEPREPASYGMMNVQARIQLAFGTSYGLTIESEAGQGTTVTIIHPLLRDGLPPVKRTSEGGT
>NC_017672.3|WP_041618517.1|7437377_7438442_-|sugar-ABC-transporter-substrate-binding-protein
MSLGKFVRTTMKGVTINPMKKLLWIYAILIGTFILYVVQYHTREVSSRAGGAHDGLRGEIGEKYVMVTFQSGMEYWKSSLKGFEDAAQALNVSVEYRGATQYDVHEQITVLEQVIAKKPEGIALSAIDPVRLTAAINKAVDAGIPVVLFDSGAPESRALSFLSTDNYNAGVTAARKMAELLGGQGEAAVVTLPGQLNHDERKQGFIDTLHKEYPQIRLQSVKDGRGDRIYSKLAAADILKEFPEVDGIFATEANGGVGVGEAVQEAEAAGKVKIIGFDTDKDTLDMVKKGAISATLAQGTWNMGYWSLQFLFHQHHGLAGPGGGTKAAASSLPRNVDTGITVVTGDNVEQFYAK
>NC_017672.3|WP_013920253.1|7439577_7440417_-|5-dehydro-4-deoxy-D-glucuronate-isomerase
MSMEIRYATNPTEAKTYDTARLRSEYVIENLFVEGQLNLVYSHVDRFITGGVIPTREPIKLEADKHDMGAEFFLERREIGIINIGAPGKVTVDGTEYVLESKDCLYVGLGNKEVLFESADAANPARFYLSSTPAHKNYPTQKVAISEAEPAHLGSITNSNERTIYKYIHLNGVQSCQLVMGMTLLKPGNMWNTMPCHTHNRRSEVYLYFDMPEDGVVFHLMGEPTETRHVVLRNEQAVISPSWSIHSGVGTSNYTFIWAMAGENQEFSDMDHVAMQDLK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_017672_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017672_17

8115633-8115815

Orphan

Consensus_repeat	Method
ATGCACTCACTCCTTTTCCTTCCACCAGCTAATC	PILER-CR

2 spacers

The CRISPR arrays of NC_017672_17

>merge|NC_017672|17|8115633-8115815|PILER-CR
ATGCACTCACCCCTCTCCTTCCACCAGCTAATCAGGCCCTTTTTACTCTCACCATCCAGCCATCCATCTCACCGAATGCACTCACTCCTTTTCCTTCCACCAGCTAACCCGAACCTGATTACTCTCACCCACAAGACATCCGTCCATCTCACGCCCTCACTCCTTTTCCTCCACCAGCTAATC

>NC_017672|17|1|8115633-8115815|PILER-CR
ATGCACTCACCCCTCTCCTTCCACCAGCTAATCA	GGCCCTTTTTACTCTCACCATCCAGCCATCCATCTCACCGAA
TGCACTCACTCCTTTTCCTTCCACCAGCTAACCC	GAACCTGATTACTCTCACCCACAAGACATCCGTCCATCTCA
CGCCCTCACTCCTTTTCCTCCACCAGCTAATC

Protein	Signature genes	Signature genes Name	Protein_function
NC_017672.3\|WP_014652912.1\|8124026_8125313_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270303
NC_017672.3\|WP_014652902.1\|8110699_8111971_-\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_017672.3\|WP_010494821.1\|8108033_8108324_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226893
NC_017672.3\|WP_016363040.1\|8120565_8122227_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|224567
NC_017672.3\|WP_014652901.1\|8109516_8110524_+\|NADPH-dehydrogenase-NamA	unknown	unknown	gnl\|CDD\|184110
NC_017672.3\|WP_014652907.1\|8118406_8119282_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NC_017672.3\|WP_013920909.1\|8112203_8112944_-\|trehalose-utilization-protein-ThuA	unknown	unknown	gnl\|CDD\|227150
NC_017672.3\|WP_014652913.1\|8125309_8128006_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NC_017672.3\|WP_014652905.1\|8116163_8116853_-\|hypothetical-protein	unknown	unknown	unknown
NC_017672.3\|WP_013920918.1\|8122989_8123244_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NC_017672.3\|WP_081668879.1\|8104554_8105922_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|129571
NC_017672.3\|WP_014652906.1\|8117052_8118264_-\|glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|369381
NC_017672.3\|WP_041618548.1\|8107032_8107809_-\|cobalamin-biosynthesis-protein-CbiX	unknown	unknown	gnl\|CDD\|225049
NC_017672.3\|WP_014652900.1\|8108679_8109297_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|316682
NC_017672.3\|WP_013920903.1\|8105998_8107024_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
NC_017672.3\|WP_014652910.1\|8122223_8122772_-\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NC_017672.3\|WP_014652911.1\|8123307_8123796_+\|YtxH-domain-containing-protein	unknown	unknown	gnl\|CDD\|378938
NC_017672.3\|WP_014652897.1\|8104102_8104555_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240035
NC_017672.3\|WP_014652908.1\|8119278_8120157_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_017672.3\|WP_014652903.1\|8113196_8114126_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117

Protein	Function_ID	Function_description	E-value
NC_017672.3\|WP_014652912.1\|8124026_8125313_-\|extracellular-solute-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.18141e-28
NC_017672.3\|WP_014652903.1\|8113196_8114126_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.49627e-23
NC_017672.3\|WP_014652902.1\|8110699_8111971_-\|two-component-sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.45049e-47
NC_017672.3\|WP_010494821.1\|8108033_8108324_-\|hypothetical-protein	gnl\|CDD\|226893	COG4496, COG4496, Uncharacterized protein conserved in bacteria [Function unknown].	4.83971e-52
NC_017672.3\|WP_016363040.1\|8120565_8122227_-\|extracellular-solute-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.19821e-09
NC_017672.3\|WP_014652906.1\|8117052_8118264_-\|glycosyl-hydrolase	gnl\|CDD\|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	1.95798e-11
NC_017672.3\|WP_014652907.1\|8118406_8119282_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.02375e-23
NC_017672.3\|WP_013920909.1\|8112203_8112944_-\|trehalose-utilization-protein-ThuA	gnl\|CDD\|227150	COG4813, ThuA, Trehalose utilization protein [Carbohydrate transport and metabolism].	9.73987e-135
NC_017672.3\|WP_014652913.1\|8125309_8128006_-\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.32995e-112
NC_017672.3\|WP_013920918.1\|8122989_8123244_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	2.23193e-07
NC_017672.3\|WP_081668879.1\|8104554_8105922_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|129571	TIGR00479, 23S_rRNA_uracil1939-C5-methyltransferase_RlmD, 23S rRNA (uracil-5-)-methyltransferase RumA. This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification].	0
NC_017672.3\|WP_041618548.1\|8107032_8107809_-\|cobalamin-biosynthesis-protein-CbiX	gnl\|CDD\|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	1.34277e-10
NC_017672.3\|WP_014652900.1\|8108679_8109297_+\|hypothetical-protein	gnl\|CDD\|316682	pfam14181, YqfQ, YqfQ-like protein. The YqfQ-like protein family includes the B. subtilis YqfQ protein, also known as VrrA, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 146 and 237 amino acids in length. There are two conserved sequence motifs: QYGP and PKLY.	0.00075324
NC_017672.3\|WP_013920903.1\|8105998_8107024_-\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	4.99179e-169
NC_017672.3\|WP_014652910.1\|8122223_8122772_-\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	2.93573e-41
NC_017672.3\|WP_014652911.1\|8123307_8123796_+\|YtxH-domain-containing-protein	gnl\|CDD\|378938	pfam12732, YtxH, YtxH-like protein. This family of proteins is found in bacteria. Proteins in this family are typically between 100 and 143 amino acids in length. The N-terminal region is the most conserved. Proteins is this family are functionally uncharacterized.	1.2547e-12
NC_017672.3\|WP_014652897.1\|8104102_8104555_-\|NUDIX-domain-containing-protein	gnl\|CDD\|240035	cd04679, Nudix_Hydrolase_20, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	6.62605e-41
NC_017672.3\|WP_014652908.1\|8119278_8120157_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.98963e-29
NC_017672.3\|WP_014652901.1\|8109516_8110524_+\|NADPH-dehydrogenase-NamA	gnl\|CDD\|184110	PRK13523, PRK13523, NADPH dehydrogenase NamA; Provisional.	0

>NC_017672.3|WP_014652903.1|8113196_8114126_+|AraC-family-transcriptional-regulator
MTNAALESPLEAINENVIYQNPLLRLKIWELYWDVPTYGIPERWRWHYHKEVEFLVVLEGQLGVQTKDDSCILGPGDVMLLGASQPHRTYKSEPTAIRQVVFQVDLAQHFDQSTMPYLSTFSELTRPLGELNYIFRENAEARQEAFRLVMDIYEESQQKQRGYEMSISSSIKRLLLLLLRSDYRGVLGRTDDTELLRLRPALDYVDRHLGEKIAVEDVCGLLNLSYHYFIKYFKKAMGLSFVDYVNYKRVKTAERLLLTRDLSIMEVGFEVGIPNMAQFYKLFKRHNQCSPKEFRQRMRSQAGPGGDGV
>NC_017672.3|WP_013920909.1|8112203_8112944_-|trehalose-utilization-protein-ThuA
MAQSKLRVTIWNEFRHEKKNEKVRAVYPNGIHTAIGEGLGDEVEVTYATLDEPEHGLTQEVLDNTDVLFWWGHIAHHEVSDEVVKRVQDRVLHGMGLIVLHSGHFSKIFKTLMGTSCDLKWREADEKERIWVVNPGHPIVEGIGEYIEFEEEEMYGEHFDIPAPDELIMVSWFEGGEVFRSGCTFTRGQGKIFYFRPGHETYPTFYNEQVRRVLSNAVKWAAPSTREYPKYGNHKPLEAIKAKTNA
>NC_017672.3|WP_014652902.1|8110699_8111971_-|two-component-sensor-histidine-kinase
MLTSLFSNILFLIFPIFLFQVFWEGRRRFNQDGPVMLMLGAGAMLLCMNFPVVMSDGYYFDFRFTVLAIAALYGSLRHSAVLVGVMVAYRWWMGGDGFFGQLFILALLFPLLMLARRKFTSRPPAVRMILVIALSIAPVPMLLLGKPLIFEDILLTWELVEQFLTVMGIQAVGTWIVIYFIEKDIEAHAIRREIRQAEKMRVISDLAASVSHEVRNPLTVARGFLQLLLTSAKSEKESRFMTLALEELDRAQEIIGDYLAYAKPDADRLEELEVEDEIRYVSGVLQPYALFGEVEIETDCPEHNWVLGERQKFRQCLINLVKNSIEAMPEGGKLRIGIHALQNKVEVRIRDNGTGMTPEEVSRLGKAFYTTKERGTGLGTMVAFSIIKAMNGRIDIHSKKGAGTEFTIVLPKVNPAEKFGSAV
>NC_017672.3|WP_014652901.1|8109516_8110524_+|NADPH-dehydrogenase-NamA
MLFTPFTIKGLTLKNRIVMSPMCMYSCMDESGLVQDWHKIHYPARAVGQVGLLIVEASAVTPQGRISVHDLGIWSDAHVEGHSELVRLVHGQGAKIGIQIAHAGRKSEVPGAIVAPSAIPFDEKSRTPEALSSEGVAETIEAFVQAARRAKEAGYDVIEIHGAHGYLINEFLSPLSNRREDGYGGDRDKRYRFLREVIDGVKTVWDGPLFVRVSTNEYHPEGNTPDDYAYYARLMKDQGVDLIDCSSGGTVPAAIKPFPGYQVPLAEKIRREAGIATGAVGLITEAQQAEEILQNERADLVFLGRELLRDPYWPRTAAKALRVEIEGPTQYGRGW
>NC_017672.3|WP_014652900.1|8108679_8109297_+|hypothetical-protein
MNYRRQTIGNGGARDTRHYAARSSNYYDGRYPGLQRAHTRSFLQGAAPSGDFTGGGVPFAGGADYPGLGGQLPATQALVPQSGGGGLGGLFGGGGGSQAGGGGLAGLLGGGGGGTGSFNIGQIKDIVDRLGGVEGIVSTFGKVQTVVQSMSQMAPMIKLLLGSFGKGKKSDAEASDDGDGLAGTRRKRRKRKGPVRGRRRRSTKR
>NC_017672.3|WP_010494821.1|8108033_8108324_-|hypothetical-protein
MQLKKLNDKAIDQLFEAILTLKDIEECYVFFDDLCTVNEIQSLSQRLEVARMLRKGNTYNQIEAETGASTATISRVKRCLNYGNDGYKMTLERLGR
>NC_017672.3|WP_041618548.1|8107032_8107809_-|cobalamin-biosynthesis-protein-CbiX
MVKYGILVISHGSRSADWVRLVDEAVDAVQLPDGVPIYSSFLEIVEGRLIQDGITHLESLGCTDLVVVPLFVSSGSTHIDEISYALGVKDAPLLPTDMEPFEIRARVHMADPMDDDAEVAEILQGKVSPLSEDPSREILLLVGHGSIEKGFHLQWRRVLEGLAVRIQALGGYAEADYAMLLPDQTAFKMRLWKKMRPDCRVIVAPVFLSEGYFTREVIPERLAGWEYRYNGAAMLPHPGISRWIERRALSYINFETNG
>NC_017672.3|WP_013920903.1|8105998_8107024_-|diacylglycerol-kinase
MAKRARLIYNPSSGREEMRKRLPDVLQRLERGGLETSTHATIGEGDATLAAAEAVERGFDIIIAAGGDGTLYEVINGMAEKDYRPPLGIIPLGTTNDFARALNIPRNWDAAVDVILRQHSRVIDVGKVNQRYFINIAGGGSMTELTYEVPSKLKTMIGQLAYYMKGLEKLPRLRPIELYIKTAEVELHEEVMLFLISNSNSVGGFERLAPDASLSDGMFDVLVLRKCNLAEFIRVVTLALRGEHLADPNVIYLQTKQIQVTSPDYVQVNLDGEFGGTLPCVFTNLPQHLHIFVDETGQSTYKTPAINLMKLPWKTKPGVDEDDEIEETDNENENYRYKIKP
>NC_017672.3|WP_081668879.1|8104554_8105922_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MVGIGHEGEGVGRVNGYTLFVPGALPGEKVRVKVVKVKKQYGYAKLLEVLEASPDRIDAPCPIYKQCGGCQLQHLSYEAQMRWKRQLVIDNLTRIGKLQVVGEREEGIIVHPTLGMSDPWRYRNKAQVPIGLAETEEGGLVGGFYAQGSHRIIDMEACLIQHENNDAVVGAVKKIARELGIRPYSEETGRGLLRHVIARYGFNTGEIMVVLVTNGRDLPHADELTGLIRRDVPGVTSIVQNINTRETNVIFGDETRTLWGSDVIYDTIGDIRFAISARSFYQVNPVQTEVLYGKALEYAALTGRETVIDAYCGIGTISLFLAQKADQVYGVEIVPEAIEDARANARLNGIRNASFEAGPAEVVIPAWRAKGIAPDVIVVDPPRKGCDPALLETILAMRPERVVYVSCNPSTLARDLRVLEDGGFRTVQVQPVDMFPHTVHVESVAVLVRGEAGEA
>NC_017672.3|WP_014652897.1|8104102_8104555_-|NUDIX-domain-containing-protein
MAETFISADATVAAVTPRMGVGAAIVNENQEILLVLRNRDPEKDTWSIPGGKLDTYERLEDCVVREIKEEVNLDIQVRGLLCMAETIRPERDEHWVSALYEAEILGGELRNMEEGGAIGDIRWFPLDALPANLACFTVPAIEQLLNRMNR
>NC_017672.3|WP_014652905.1|8116163_8116853_-|hypothetical-protein
MDRLGSGSGAWEQTYEAYMEEQRKSASGERRRRLRERQGHAERRFVENVWWPAVGSWDYLQAEYQVQDFRDGTRFLDYAYLRPPYKICIEIDGYGPHQRDTTRWQFADGLYRQNQLVLDDWKVLRFAYDDIMEKPRRCQQLIQQFLGRWYGEEVFPAALSLREKDILRFVLREQRAITPAEAAGHLGISTRYARELLQQLVEQRLLLPASGSQRVRAYKLNPQGKPAVW
>NC_017672.3|WP_014652906.1|8117052_8118264_-|glycosyl-hydrolase
MAGGAGAMDGAAGQGAFSLKEERAGRAWADARQLGDILPEVWTALQAKVSRMIGQIGDKSPHVARPETGVYDDLQVDWWTSGFWPGLLWILHDRTGEAAYREAAWPWDEKMERRMIEANRYHHDVGFQFLPTAVIKYKLTGDPDGLRRGLQAANFLAGRFNPAGRFLRAWNEDKIGWSIVDSSMNLSLLFWASEESGDPRFAQIARAHADTVVAHFIREDGSVNHIVSFDPHTGAVIESLGGQGAAPDSSWSRGAAWALHGMANTYRYTGDRRYLQAARRVAHYFLACLPEDGVPHWDFRAAADLSGEPRDTSAGACAASGLLELAEALPGPEGAVYRQGAERILLGLTQHYGTWDRPAHEAILLSGTGHKPAGQNVDVSLIYGDYYYVEAIAKLMGWERRIF
>NC_017672.3|WP_014652907.1|8118406_8119282_+|AraC-family-transcriptional-regulator
MPILKLTNYLNLNTHPVRLSFRKERTGGLVDYYHAHQGLELLYVHEGGGRAVVEQQIIEMIPGLILVFKPYQLHRIHVLPQPGRPYIRSLFVLEPDVLERSLEPFGRLQAFLRRLWKDPLAPYAFQSENPTSGDLLLSLYEHRLESYEASPARLEEQLLFLTAFTDYIRSACIPVAAAPADQQGPKGSAAAEKMMAWVESHYARPFELAELARAVHLSPNHASAVFRKYVGSSITEYLAARRVRQACWLLRTTDLPVQEIGREVGLGSFSYFCQLFKKHVGQSPHRFRKEG
>NC_017672.3|WP_014652908.1|8119278_8120157_-|helix-turn-helix-transcriptional-regulator
MEQGQLQIMRSYLDNVQMTLDTVHYTKVGTNWRYRFENPEENRFYFIREGSGWIRLRGRLHHPKPGELLLLPAGAKLELGLCGEEERFGKHWCHFGAKVGDVHLFQMLDLPFSIRVGDEDWLERQFRALEALYRSPSLTAPLRIKSVLLELVSYYMEEALRQQDSQSIALAPSAAEGKITAVLHYIDTHLSEGITVEELARQMHFHPNYFMPYFKTMMGLSPIAYITRKRMDKAKELLRDTEVPVTEVAEAVGLELAYFSRLFKKQTALSPTQYRRNARGPRTEASSVSVPD
>NC_017672.3|WP_016363040.1|8120565_8122227_-|extracellular-solute-binding-protein
MKRKLDTPAWEQRLGSRPPLKEGGYSRELEGRVMQRVAAGPRPGRRRLIRWSPLLACGLMIAIGIGQAEQLAGWAGRLGGKEQADGSSLNGGKPFTLRVAADSAADFMAAYGEAFEQKYPNAQLEVIPLKGRGLTRTGAEQPRGDWFADQRPDVLELEADRTYSALAAEGRLQTLETLSQEEGWERGRMHPGVTAALRSLGGGALYGIAPEYEQLALYYNPSLFEQYGIPLPRDGMNRGQLIEAASRLAQAGGEGEDRIYGLAFDGGLSFLEGLVQSAAAEEPGLLDPQGRVDLQEMEWRRLWEQAVEAVRGGAVYVPGAAVRAADSGKKAEPKSGAADVKKAAETRDAAGSPGVDRAAAPADGGESRTAGLSALELFLQGRAAMVLGPYDLARRLDEAARRAPDNKAAAGWNIVTEPQISPGQTNESASFRLRRVYAAAAESPQPEAALALVKYIAGEEAAKRRAAAAGEQHLPSRLPGLTLRLLQGKHAEAFYRLQPPQAQASAGLPSLLADALPLLAAERFAAAAAGRQTADAALRQLEAELQAVLDGAK
>NC_017672.3|WP_014652910.1|8122223_8122772_-|RNA-polymerase-sigma-factor
MAFEYLKSLSGGMDRSCVLSELMGAYGEDVWNYAFFLTRDHALSDDITQDVFVKVYEKMYSFRGESSVRTWLLAITRNLVRDHWRSAWFRRVIPFGSPKREEHGPSAESLAVSSLVTEEVWAAVLALPRKLREVLLLHAHHGLSHAEIAALLDLSQGTVKSRLSRARTKVSKELNREGGERT
>NC_017672.3|WP_013920918.1|8122989_8123244_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MSWIIMIIMAIIIGVIGSAIAPGRMPGGILGSMIAGFVGAWIGGMLLGSWGPQLGGFSIVPAIIGAALFVLILSLLARGMNRAA
>NC_017672.3|WP_014652911.1|8123307_8123796_+|YtxH-domain-containing-protein
MSTVNTTESRSSSLLLGTVVGAATGALVALLMAPKTGRELRSDLMEVVNTIQTKGAEYMAMAKEKAADTASMVKEKAADTATMVKERGSELIEKAQQTTTTAADASHEAIDQAASVSEQKLNQAADSAHKALESASSAAQSSLDKAEDKTDHSTSSYSTTRY
>NC_017672.3|WP_014652912.1|8124026_8125313_-|extracellular-solute-binding-protein
MTRRNRTAALAVLTLVTLLTASCGGAVQDSAALLPKAAPLERAYRSVSTAKQLTIWTYYNITKDVERFRSEHPDVQVNVATFANGSYVEAYLDGLAGGSPPDLLLLDNRDIGAFNTIDGLEDLLQPPYGGQSYKAAIPGNVWKLYSSFDRERMISLPIELPTAATYYRRDLIESLGLPGDPAELGVYLENPEHWLELARKLKAQDRYIFQWEAEPVEVAAMQGNYLQEDLNFARNKPVYQQAMEVAKTVHREGLALRSSVQTDPGQEALRSGRLAMVYLGRWGADSLERWAPETKGLWSVTRLPMNLYGWNGGSSLAISSRSQSKELAWAFARMATQLGAPRPDSGFLDMSPFDVLYTYGQTFVERQTPSPFDRKLEELWTESVTDILENGTHSGSGLRFIESQANSIIEKDRERLLRYLGKNKLERP
>NC_017672.3|WP_014652913.1|8125309_8128006_-|EAL-domain-containing-protein
MEFLRRIRHQRSLPFLMGAALYGLSAASVLQSIPMIFGLHFTFAGVFIMIALRLYGILPAVFLSVVTLVTGMFFVGFAPAFLFTVIEVMFVGWMMRRRTEHLLIADLIYWITVGWLITGGAYYADTGRMGVDLLLLLFKSVVNGTFNALIADIAMAYLPLRRMAGQRLPEAESGISLQQILFHIVMVALMVPFVLFMIIVSWYQNNSMVERAGVLTEGLAAQLNQELRTWGEEELRGLRLHSLVELSRLNEVLVQMGDKAGVRSYVLDTRDAVVASNVAGRIQKPWEWPAGWQMYPMEAEGLYLGKPAPGSRLYEMAAWEESSFYYSKTLNGLPYLLLLEVPMHVFLEELQPVHTLNYSLVLLFIFLAVMATLLISRRLTRVLHLLGQATADLPQKLREEGEIHWPETRVTEVHRLTTNFRAMSGELLKMFLETVRMNSRLQSQTMQLRESERRLEQLAYYDMLTGLPNRLHFSKYLSEWMEQPAEPGLSAAVLFLDLDRFKQINDTFGHSAGDELIIDVAKKLSGGVRYAPVFRLGGDEFVVLASHRRREEVVETAEAILAALSEPVILQGQEIFVRSSIGISIFPGDAQDAEALLKNADDAMYEAKERGGGQYAFYSEATSESAAERLQLEQALHRALAAGEFELFYQPQYGGTDGRINGMEALIRWKHPAEGYIPPVRFIPLAEQTGEIRSIGEWVLREACLQGKRLQEHAPGLLTAVNLSPRQLDQPDLVERVRAILQETGMPAGLLELEITEEFFIRNQDKAEAALQQFKEMGIRLAIDDFGTGYSSFAQMKRIMPDTLKIDRSFIRGLDQDASNASIVQALITMAHSLKLKVVGEGVETEEELLSLRRFGCDEIQGYYYSKPLPLAELEALLKGAPSAASSDEDREERRGDS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017672_13	13.1\|7096641\|27\|NC_017672\|CRISPRCasFinder	7096641-7096667	27	NC_017672.3	3057197-3057223	1	0.963
NC_017672_13	13.1\|7096641\|27\|NC_017672\|CRISPRCasFinder	7096641-7096667	27	NC_017672.3	3124196-3124222	1	0.963
NC_017672_15	15.10\|7263552\|21\|NC_017672\|CRT	7263552-7263572	21	NC_017672.3	2137552-2137572	2	0.905

1. spacer 13.1|7096641|27|NC_017672|CRISPRCasFinder matches to position: 3057197-3057223, mismatch: 1, identity: 0.963

tcgactatttcccatcatttcccgaag	CRISPR spacer
tcggctatttcccatcatttcccgaag	Protospacer
***.***********************

2. spacer 13.1|7096641|27|NC_017672|CRISPRCasFinder matches to position: 3124196-3124222, mismatch: 1, identity: 0.963

tcgactatttcccatcatttcccgaag	CRISPR spacer
tcgagtatttcccatcatttcccgaag	Protospacer
**** **********************

3. spacer 15.10|7263552|21|NC_017672|CRT matches to position: 2137552-2137572, mismatch: 2, identity: 0.905

cgccggcagcacgcctgcgtt	CRISPR spacer
cgccggcagcgcgcctccgtt	Protospacer
**********.***** ****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017672_15	15.8\|7263474\|21\|NC_017672\|CRT	7263474-7263494	21	NZ_CP021827	Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence	375384-375404	2	0.905
NC_017672_9	9.1\|6798256\|26\|NC_017672\|CRISPRCasFinder	6798256-6798281	26	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	213152-213177	3	0.885
NC_017672_6	6.1\|3770243\|26\|NC_017672\|CRISPRCasFinder	3770243-3770268	26	MK733259	Yersinia phage YeP1, complete genome	13094-13119	4	0.846
NC_017672_6	6.1\|3770243\|26\|NC_017672\|CRISPRCasFinder	3770243-3770268	26	MK733261	Yersinia phage YeP3, complete genome	13105-13130	4	0.846
NC_017672_6	6.1\|3770243\|26\|NC_017672\|CRISPRCasFinder	3770243-3770268	26	MK733260	Yersinia phage YeP2, complete genome	13105-13130	4	0.846
NC_017672_9	9.1\|6798256\|26\|NC_017672\|CRISPRCasFinder	6798256-6798281	26	NZ_CP016618	Microvirga ossetica strain V5/3m plasmid unnamed3, complete sequence	614612-614637	4	0.846
NC_017672_9	9.1\|6798256\|26\|NC_017672\|CRISPRCasFinder	6798256-6798281	26	MH791409	UNVERIFIED: Escherichia phage EcWhh-1, complete genome	30135-30160	5	0.808
NC_017672_9	9.1\|6798256\|26\|NC_017672\|CRISPRCasFinder	6798256-6798281	26	KP007359	Enterobacteria phage vB_EcoM_VR5, complete genome	139493-139518	5	0.808
NC_017672_9	9.1\|6798256\|26\|NC_017672\|CRISPRCasFinder	6798256-6798281	26	MK310184	Phage NC-G, complete genome	82148-82173	5	0.808
NC_017672_11	11.1\|6947410\|27\|NC_017672\|CRISPRCasFinder	6947410-6947436	27	NZ_CP031696	Erwinia billingiae strain TH88 plasmid unnamed1, complete sequence	18250-18276	6	0.778
NC_017672_13	13.1\|7096641\|27\|NC_017672\|CRISPRCasFinder	7096641-7096667	27	NZ_CP032306	Salmonella enterica subsp. enterica serovar Braenderup strain FORC93 plasmid unnamed2, complete sequence	21493-21519	6	0.778
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	NZ_CP028099	Synechocystis sp. IPPAS B-1465 plasmid pSYSM, complete sequence	47461-47488	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	NC_005229	Synechocystis sp. PCC 6803 plasmid pSYSM, complete sequence	47461-47488	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	MG962376	Mycobacterium phage Thumb, complete genome	34432-34459	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	KJ567046	Mycobacterium phage Damien, complete genome	34435-34462	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	MN010756	Mycobacterium phage Phreeze, complete genome	34435-34462	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	NC_023578	Mycobacterium phage Oaker, complete genome	34692-34719	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	MT521996	Mycobacterium phage Beckerton, complete genome	34969-34996	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	MH509445	Mycobacterium phage Cborch11, complete genome	34434-34461	7	0.75
NC_017672_2	2.1\|1547321\|28\|NC_017672\|CRISPRCasFinder	1547321-1547348	28	NC_011292	Mycobacterium phage Konstantine, complete genome	35636-35663	7	0.75
NC_017672_3	3.2\|3108879\|33\|NC_017672\|CRT	3108879-3108911	33	MN103401	Bordetella phage vB_BbrS_PHB09, complete genome	7149-7181	7	0.788
NC_017672_3	3.4\|3108992\|33\|NC_017672\|CRT	3108992-3109024	33	MN103401	Bordetella phage vB_BbrS_PHB09, complete genome	7149-7181	7	0.788
NC_017672_5	5.1\|3600570\|34\|NC_017672\|CRISPRCasFinder	3600570-3600603	34	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	1652316-1652349	8	0.765
NC_017672_5	5.1\|3600570\|34\|NC_017672\|CRISPRCasFinder	3600570-3600603	34	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	1809186-1809219	8	0.765
NC_017672_3	3.6\|3109105\|32\|NC_017672\|CRT	3109105-3109136	32	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	225596-225627	9	0.719

1. spacer 15.8|7263474|21|NC_017672|CRT matches to NZ_CP021827 (Sinorhizobium meliloti strain KH35c plasmid psymA, complete sequence) position: , mismatch: 2, identity: 0.905

cgccgacagcatgcctgcgtt	CRISPR spacer
cgccgacagcatgcctgcgac	Protospacer
******************* .

2. spacer 9.1|6798256|26|NC_017672|CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 3, identity: 0.885

gcctgaaaacgaagccctcg-cagcaa	CRISPR spacer
gcctgaaatcgaagccctcgccagcg-	Protospacer
******** *********** ****.

3. spacer 6.1|3770243|26|NC_017672|CRISPRCasFinder matches to MK733259 (Yersinia phage YeP1, complete genome) position: , mismatch: 4, identity: 0.846

cgggctgatgtgaagcgcgatattcg	CRISPR spacer
cgtgctgatgtgaatcgcgatatcag	Protospacer
** *********** ********. *

4. spacer 6.1|3770243|26|NC_017672|CRISPRCasFinder matches to MK733261 (Yersinia phage YeP3, complete genome) position: , mismatch: 4, identity: 0.846

cgggctgatgtgaagcgcgatattcg	CRISPR spacer
cgtgctgatgtgaatcgcgatatcag	Protospacer
** *********** ********. *

5. spacer 6.1|3770243|26|NC_017672|CRISPRCasFinder matches to MK733260 (Yersinia phage YeP2, complete genome) position: , mismatch: 4, identity: 0.846

cgggctgatgtgaagcgcgatattcg	CRISPR spacer
cgtgctgatgtgaatcgcgatatcag	Protospacer
** *********** ********. *

6. spacer 9.1|6798256|26|NC_017672|CRISPRCasFinder matches to NZ_CP016618 (Microvirga ossetica strain V5/3m plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.846

gcctgaaaacgaagccctcgcagcaa	CRISPR spacer
atctgaaaacgaagaccacgcagcaa	Protospacer
..************ ** ********

7. spacer 9.1|6798256|26|NC_017672|CRISPRCasFinder matches to MH791409 (UNVERIFIED: Escherichia phage EcWhh-1, complete genome) position: , mismatch: 5, identity: 0.808

gcctgaaaacgaagccctcgcagcaa	CRISPR spacer
ccctgaaaacgaagccttcgctgctc	Protospacer
 ***************.**** **

8. spacer 9.1|6798256|26|NC_017672|CRISPRCasFinder matches to KP007359 (Enterobacteria phage vB_EcoM_VR5, complete genome) position: , mismatch: 5, identity: 0.808

gcctgaaaacgaagccctcgcagcaa	CRISPR spacer
ccctgaaaacgaagccttcgcggccc	Protospacer
 ***************.****.**

9. spacer 9.1|6798256|26|NC_017672|CRISPRCasFinder matches to MK310184 (Phage NC-G, complete genome) position: , mismatch: 5, identity: 0.808

gcctgaaaacgaagccctcgcagcaa	CRISPR spacer
ccctgaaaacgaagccttcgctgctc	Protospacer
 ***************.**** **

10. spacer 11.1|6947410|27|NC_017672|CRISPRCasFinder matches to NZ_CP031696 (Erwinia billingiae strain TH88 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

ccggttatttcccgttatttcccggag	CRISPR spacer
tacattattgcccgctatttcccggag	Protospacer
.  .***** ****.************

11. spacer 13.1|7096641|27|NC_017672|CRISPRCasFinder matches to NZ_CP032306 (Salmonella enterica subsp. enterica serovar Braenderup strain FORC93 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

tcgactatttcccatcatttcccgaag	CRISPR spacer
tattgtatttcccatgatttcccgaat	Protospacer
*    ********** **********

12. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to NZ_CP028099 (Synechocystis sp. IPPAS B-1465 plasmid pSYSM, complete sequence) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ttgttgggaaattacgggaaacatgacc	Protospacer
************ ********.*. .

13. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to NC_005229 (Synechocystis sp. PCC 6803 plasmid pSYSM, complete sequence) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ttgttgggaaattacgggaaacatgacc	Protospacer
************ ********.*. .

14. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to MG962376 (Mycobacterium phage Thumb, complete genome) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ctgttcggaaacgacgggaaatacatcc	Protospacer
.**** *****.************

15. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to KJ567046 (Mycobacterium phage Damien, complete genome) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ctgttcggaaacgacgggaaatacatcc	Protospacer
.**** *****.************

16. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to MN010756 (Mycobacterium phage Phreeze, complete genome) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ctgttcggaaacgacgggaaatacatcc	Protospacer
.**** *****.************

17. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to NC_023578 (Mycobacterium phage Oaker, complete genome) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ctgttcggaaacgacgggaaatacatcc	Protospacer
.**** *****.************

18. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to MT521996 (Mycobacterium phage Beckerton, complete genome) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ctgttcggaaacgacgggaaatacatcc	Protospacer
.**** *****.************

19. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to MH509445 (Mycobacterium phage Cborch11, complete genome) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ctgttcggaaacgacgggaaatacatcc	Protospacer
.**** *****.************

20. spacer 2.1|1547321|28|NC_017672|CRISPRCasFinder matches to NC_011292 (Mycobacterium phage Konstantine, complete genome) position: , mismatch: 7, identity: 0.75

ttgttgggaaatgacgggaaataccggg	CRISPR spacer
ctgttcggaaacgacgggaaatacatcc	Protospacer
.**** *****.************

21. spacer 3.2|3108879|33|NC_017672|CRT matches to MN103401 (Bordetella phage vB_BbrS_PHB09, complete genome) position: , mismatch: 7, identity: 0.788

agcggccaatccgcccccagcaagctggctaac	CRISPR spacer
aaagcccaatccaccgccagcaagctggccgac	Protospacer
*. * *******.** *************..**

22. spacer 3.4|3108992|33|NC_017672|CRT matches to MN103401 (Bordetella phage vB_BbrS_PHB09, complete genome) position: , mismatch: 7, identity: 0.788

agcggccaatccgcccccagcaagctggctaac	CRISPR spacer
aaagcccaatccaccgccagcaagctggccgac	Protospacer
*. * *******.** *************..**

23. spacer 5.1|3600570|34|NC_017672|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 8, identity: 0.765

ctgccgggcccactctgtgcttttttggccttgt	CRISPR spacer
ctgcctggcccacgctgtgcttttcagcgctctt	Protospacer
***** ******* **********. *  **. *

24. spacer 5.1|3600570|34|NC_017672|CRISPRCasFinder matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 8, identity: 0.765

ctgccgggcccactctgtgcttttttggccttgt	CRISPR spacer
ctgcctggcccacgctgtgcttttcagcgctctt	Protospacer
***** ******* **********. *  **. *

25. spacer 3.6|3109105|32|NC_017672|CRT matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

agcggccaatccgccctcggcaggccggcgaa	CRISPR spacer
cgcggccaattcgcgctcggcaggcagagcgc	Protospacer
 *********.*** ********** *.  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

849902 : 899435

Synechococcus_phage(25.0%)

transposase,protease,coat

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014649381.1\|849902_850262_+\|coat	spore coat protein	NA	NA	NA	NA
WP_014649382.1\|850282_851419_+	glutathione-dependent formaldehyde dehydrogenase	E3SJ82	Synechococcus_phage	3.8e-14	24.8
WP_014649383.1\|851431_851635_+	hypothetical protein	NA	NA	NA	NA
WP_014649384.1\|851652_851946_+\|coat	spore coat protein	NA	NA	NA	NA
WP_051220053.1\|851979_852204_+	hypothetical protein	NA	NA	NA	NA
WP_014649386.1\|852226_852553_+\|coat	spore coat protein	NA	NA	NA	NA
WP_014649387.1\|852924_853488_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_014649388.1\|853498_854587_+	DUF418 domain-containing protein	NA	NA	NA	NA
WP_013914587.1\|854792_854939_-	hypothetical protein	NA	NA	NA	NA
WP_014649389.1\|855170_856808_+	alkaline phosphatase	NA	NA	NA	NA
WP_014649390.1\|856930_857722_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_041618582.1\|858046_858808_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_014649393.1\|858912_860358_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_014649394.1\|860483_861125_+	LysE family transporter	NA	NA	NA	NA
WP_014649395.1\|861275_863324_+	molybdopterin oxidoreductase family protein	A0A077SK27	Escherichia_phage	4.3e-56	28.8
WP_013914596.1\|864503_865010_-	chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	7.9e-12	46.7
WP_014649397.1\|865154_866522_-	APC family permease	NA	NA	NA	NA
WP_014649398.1\|867042_867759_+	urea carboxylase-associated family protein	NA	NA	NA	NA
WP_014368494.1\|867846_868497_+	DUF1989 domain-containing protein	NA	NA	NA	NA
WP_016362291.1\|868526_872159_+	urea carboxylase	NA	NA	NA	NA
WP_014649399.1\|872158_873973_+	allophanate hydrolase	NA	NA	NA	NA
WP_014649400.1\|874437_874983_+	hypothetical protein	NA	NA	NA	NA
WP_014368496.1\|875578_876760_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_014649401.1\|876836_879230_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_041618165.1\|879235_881380_+	molybdopterin oxidoreductase family protein	NA	NA	NA	NA
WP_016362292.1\|882624_884682_+	LTA synthase family protein	NA	NA	NA	NA
WP_013914610.1\|884768_885065_-	hypothetical protein	NA	NA	NA	NA
WP_014649403.1\|885176_886724_+	copper amine oxidase N-terminal domain-containing protein	NA	NA	NA	NA
WP_013914612.1\|887095_888220_-	hypothetical protein	NA	NA	NA	NA
WP_014368502.1\|888479_890450_+	sensor histidine kinase	NA	NA	NA	NA
WP_016362293.1\|890584_892021_-	aspartate ammonia-lyase	NA	NA	NA	NA
WP_016362294.1\|892054_893320_-	cation:dicarboxylase symporter family transporter	NA	NA	NA	NA
WP_016362295.1\|893614_894901_+	sensor histidine kinase	NA	NA	NA	NA
WP_014649406.1\|894907_895843_+	response regulator	NA	NA	NA	NA
WP_014649407.1\|896408_897806_+	pectate lyase	NA	NA	NA	NA
WP_014650466.1\|898266_898563_+\|transposase	transposase	NA	NA	NA	NA
WP_128758894.1\|898532_899435_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.5e-50	40.0

DBSCAN-SWA_2

1688819 : 1776517

Bacillus_phage(37.93%)

transposase,tail,portal,terminase,head,integrase,protease,capsid,coat

attL 1689823:1689838|attR 1755996:1756011

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014369062.1\|1688819_1689023_+\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
WP_014649850.1\|1689043_1689310_+\|coat	spore coat protein CotJB	NA	NA	NA	NA
WP_014649851.1\|1689346_1689565_+	protein CotJC1	NA	NA	NA	NA
WP_014649852.1\|1689646_1690528_-	hypothetical protein	NA	NA	NA	NA
1689823:1689838	attL	NA	NA	NA	NA
WP_014649854.1\|1692307_1693726_+	TIR domain-containing protein	NA	NA	NA	NA
WP_164923369.1\|1693848_1693989_+	hypothetical protein	NA	NA	NA	NA
WP_014649855.1\|1693970_1694345_-	helix-turn-helix domain-containing protein	S6C481	Thermus_phage	1.9e-18	50.0
WP_014649856.1\|1694499_1694748_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_128758907.1\|1694823_1695099_+	hypothetical protein	NA	NA	NA	NA
WP_014649858.1\|1695253_1695751_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014649859.1\|1695740_1696016_+	hypothetical protein	NA	NA	NA	NA
WP_014649860.1\|1695993_1696236_+	DUF2538 family protein	NA	NA	NA	NA
WP_014649862.1\|1696600_1697632_+	DnaD domain protein	A0A0K2CY85	Paenibacillus_phage	4.5e-30	57.5
WP_014649863.1\|1697612_1697951_+	hypothetical protein	NA	NA	NA	NA
WP_014649864.1\|1697962_1698190_+	hypothetical protein	NA	NA	NA	NA
WP_014649865.1\|1698205_1698658_+	hypothetical protein	NA	NA	NA	NA
WP_014649866.1\|1698673_1698925_+	hypothetical protein	NA	NA	NA	NA
WP_014649867.1\|1698914_1699112_+	hypothetical protein	NA	NA	NA	NA
WP_014649868.1\|1699183_1699465_-	hypothetical protein	NA	NA	NA	NA
WP_164923370.1\|1699566_1699734_+	hypothetical protein	NA	NA	NA	NA
WP_128758909.1\|1699756_1699963_+	hypothetical protein	NA	NA	NA	NA
WP_128758910.1\|1700041_1700410_-	hypothetical protein	NA	NA	NA	NA
WP_014649870.1\|1700942_1701320_+	hypothetical protein	NA	NA	NA	NA
WP_014649871.1\|1702046_1702619_+\|integrase	tyrosine-type recombinase/integrase	W8CYP1	Bacillus_phage	2.0e-40	48.4
WP_014649872.1\|1702798_1704676_+	DEAD/DEAH box helicase family protein	A0A2K9V3E9	Faecalibacterium_phage	1.3e-11	30.5
WP_014649873.1\|1704681_1705011_+	hypothetical protein	NA	NA	NA	NA
WP_014649874.1\|1705080_1705431_+	HNH endonuclease	A0A1U7Q1S7	Geobacillus_virus	3.8e-21	45.0
WP_014649876.1\|1706339_1706888_+	hypothetical protein	NA	NA	NA	NA
WP_016362384.1\|1707001_1707502_+\|terminase	phage terminase small subunit P27 family	A0A2H4J8E3	uncultured_Caudovirales_phage	1.1e-45	59.7
WP_014649878.1\|1707501_1709226_+\|terminase	terminase large subunit	A0A0S2GLF0	Bacillus_phage	1.7e-175	53.4
WP_014649879.1\|1709259_1710525_+\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	2.8e-82	47.3
WP_014649880.1\|1710481_1711186_+\|head,protease	HK97 family phage prohead protease	E2ELI4	Clostridium_phage	1.4e-35	51.2
WP_014649881.1\|1711187_1712354_+\|capsid	phage major capsid protein	A0A1B1P7R4	Bacillus_phage	1.5e-98	48.8
WP_014649882.1\|1712370_1712682_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_128758911.1\|1712626_1712878_+	hypothetical protein	NA	NA	NA	NA
WP_016362385.1\|1712858_1713209_+\|head	phage head closure protein	A6M954	Geobacillus_virus	1.1e-15	34.0
WP_014649885.1\|1713177_1713567_+	HK97 gp10 family phage protein	W8CZ44	Bacillus_phage	6.5e-22	44.4
WP_014649886.1\|1713563_1713926_+	DUF3168 domain-containing protein	Q2I8F3	Bacillus_phage	2.3e-29	54.9
WP_014649887.1\|1713929_1714562_+\|tail	tail protein	A0A1G5SA63	Enterococcus_phage	1.9e-26	38.0
WP_014649888.1\|1714567_1714966_+	hypothetical protein	A0A0S2SXM1	Bacillus_phage	6.0e-23	43.9
WP_014649889.1\|1714952_1716566_+	hypothetical protein	A0A2D1GD28	Mycobacterium_phage	1.4e-06	46.5
WP_016362386.1\|1716622_1716925_+	hypothetical protein	A0A288WFU2	Bacillus_phage	6.4e-09	35.5
WP_081668793.1\|1716921_1717101_+	hypothetical protein	NA	NA	NA	NA
WP_016362388.1\|1717124_1721570_+	hypothetical protein	A0A0S2SXL7	Bacillus_phage	4.2e-72	34.2
WP_014649891.1\|1721562_1722414_+\|tail	phage tail family protein	A0A0K2CZA8	Paenibacillus_phage	8.9e-40	32.3
WP_014649892.1\|1722416_1723544_+	hypothetical protein	A0A0K2CZQ1	Paenibacillus_phage	3.2e-53	33.9
WP_014649893.1\|1723545_1725255_+	hypothetical protein	NA	NA	NA	NA
WP_014649894.1\|1725267_1725543_+	hypothetical protein	NA	NA	NA	NA
WP_014649895.1\|1725564_1725708_+	hypothetical protein	NA	NA	NA	NA
WP_014649896.1\|1725738_1726077_+	hypothetical protein	NA	NA	NA	NA
WP_014649897.1\|1726086_1727478_+	hypothetical protein	Q9ZXD7	Bacillus_phage	7.0e-18	38.1
WP_014649898.1\|1727480_1727876_+	hypothetical protein	NA	NA	NA	NA
WP_164923371.1\|1728092_1728575_-	DUF3231 family protein	NA	NA	NA	NA
WP_014649900.1\|1728809_1730372_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_014649901.1\|1731047_1731431_+	hypothetical protein	NA	NA	NA	NA
WP_014649902.1\|1732008_1732368_-	hypothetical protein	NA	NA	NA	NA
WP_014649903.1\|1733063_1733336_-	HU family DNA-binding protein	NA	NA	NA	NA
WP_014649904.1\|1733557_1734472_+\|integrase	tyrosine-type recombinase/integrase	A0A0A7AR08	Bacillus_phage	1.1e-83	55.7
WP_128758913.1\|1734978_1737558_-	hypothetical protein	NA	NA	NA	NA
WP_014369134.1\|1738383_1739661_-\|transposase	IS110 family transposase	A0A1X9I5Z0	Streptococcus_phage	1.8e-15	25.6
WP_014649907.1\|1739908_1740331_+	hypothetical protein	NA	NA	NA	NA
WP_014649908.1\|1740638_1741001_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014649909.1\|1741213_1741798_+	NAD(P)H oxidoreductase	NA	NA	NA	NA
WP_014649910.1\|1743690_1745082_-	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	5.3e-66	38.9
WP_014649911.1\|1745201_1745639_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014649912.1\|1745782_1746553_+	isocitrate lyase/phosphoenolpyruvate mutase family protein	NA	NA	NA	NA
WP_014370420.1\|1746694_1747159_+	DinB family protein	NA	NA	NA	NA
WP_014649913.1\|1747486_1748491_-	DUF3231 family protein	NA	NA	NA	NA
WP_014369134.1\|1749163_1750441_-\|transposase	IS110 family transposase	A0A1X9I5Z0	Streptococcus_phage	1.8e-15	25.6
WP_014649360.1\|1751789_1752167_+	hypothetical protein	NA	NA	NA	NA
WP_016362393.1\|1753340_1753580_+	hypothetical protein	NA	NA	NA	NA
WP_014649914.1\|1755283_1755598_+	hypothetical protein	NA	NA	NA	NA
WP_014649915.1\|1755768_1755987_+	hypothetical protein	NA	NA	NA	NA
WP_016362394.1\|1756306_1757296_-	DUF3231 family protein	NA	NA	NA	NA
1755996:1756011	attR	NA	NA	NA	NA
WP_016362395.1\|1757643_1758195_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_016362396.1\|1758359_1759286_+	ketopantoate reductase family protein	NA	NA	NA	NA
WP_016362397.1\|1759677_1761648_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.0e-06	40.7
WP_041618605.1\|1765006_1766050_+	DUF3231 family protein	NA	NA	NA	NA
WP_128759021.1\|1766577_1767337_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.4e-44	69.6
WP_016362398.1\|1767397_1769188_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.7e-06	40.7
WP_016362395.1\|1769457_1770009_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_016362399.1\|1770173_1771100_+	ketopantoate reductase family protein	NA	NA	NA	NA
WP_014649668.1\|1771601_1772867_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_081668863.1\|1773152_1773740_+	AAA family ATPase	NA	NA	NA	NA
WP_128759022.1\|1774074_1775086_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	5.8e-22	26.9
WP_016362402.1\|1775314_1776517_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

3448782 : 3459218

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013916445.1\|3448782_3449214_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	4.2e-22	43.7
WP_014650769.1\|3449813_3450926_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.7e-54	40.3
WP_014650770.1\|3450964_3451633_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	7.0e-40	44.4
WP_013916448.1\|3451697_3452936_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	9.3e-115	53.0
WP_013916449.1\|3452972_3453443_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-41	57.4
WP_014650771.1\|3453485_3454271_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	8.2e-08	32.1
WP_013916451.1\|3454239_3454857_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.4e-15	35.6
WP_013916452.1\|3454979_3455663_+	DUF2953 domain-containing protein	NA	NA	NA	NA
WP_013916453.1\|3455811_3456318_+	sporulation protein YtfJ	NA	NA	NA	NA
WP_014650773.1\|3456752_3459218_+	EAL domain-containing protein	G3MA91	Bacillus_virus	7.5e-23	35.0

DBSCAN-SWA_4

3691161 : 3708747

Bacillus_phage(43.75%)

tail,portal,terminase,head,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014650872.1\|3691161_3691515_+	HNH endonuclease	A0A0K2CYS9	Paenibacillus_phage	4.2e-20	52.7
WP_128758952.1\|3691605_3691887_+	hypothetical protein	NA	NA	NA	NA
WP_016362596.1\|3692201_3692702_+\|terminase	phage terminase small subunit P27 family	A0A2H4J8E3	uncultured_Caudovirales_phage	1.8e-45	59.7
WP_016362597.1\|3692701_3694426_+\|terminase	terminase large subunit	A0A0S2GLF0	Bacillus_phage	2.7e-176	53.8
WP_016362598.1\|3694463_3695729_+\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	1.2e-80	45.8
WP_014650875.1\|3695685_3696390_+\|head,protease	HK97 family phage prohead protease	E2ELI4	Clostridium_phage	5.4e-35	51.8
WP_014650876.1\|3696391_3697558_+\|capsid	phage major capsid protein	A0A1B1P7R4	Bacillus_phage	9.5e-101	49.9
WP_014650877.1\|3697574_3697886_+\|head,tail	phage gp6-like head-tail connector protein	A0A1B1P7Q8	Bacillus_phage	4.5e-10	45.6
WP_014650878.1\|3697875_3698082_+	hypothetical protein	NA	NA	NA	NA
WP_014650879.1\|3698062_3698413_+\|head	phage head closure protein	A6M954	Geobacillus_virus	2.8e-16	35.9
WP_014650881.1\|3698766_3699129_+	DUF3168 domain-containing protein	Q2I8F3	Bacillus_phage	3.9e-29	54.9
WP_014650882.1\|3699132_3699747_+\|tail	tail protein	A0A2H4J8F3	uncultured_Caudovirales_phage	1.8e-34	42.0
WP_014650883.1\|3699770_3700169_+	hypothetical protein	A0A0S2SXM1	Bacillus_phage	4.6e-23	45.5
WP_014650884.1\|3700155_3701769_+	hypothetical protein	A0A2D1GD28	Mycobacterium_phage	4.9e-07	46.5
WP_014650885.1\|3701825_3702128_+	hypothetical protein	A0A288WFU2	Bacillus_phage	3.7e-09	35.5
WP_016362600.1\|3702327_3706773_+	hypothetical protein	A0A1G5SB90	Enterococcus_phage	2.1e-44	37.2
WP_041618659.1\|3706765_3707617_+\|tail	phage tail family protein	A0A2I7SBZ7	Paenibacillus_phage	5.2e-40	32.6
WP_014650888.1\|3707619_3708747_+	hypothetical protein	A0A0K2CZQ1	Paenibacillus_phage	5.4e-53	34.4

DBSCAN-SWA_5

8173553 : 8182672

Mollivirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014652933.1\|8173553_8174597_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	4.8e-72	46.8
WP_051220122.1\|8175557_8177066_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.3e-51	32.6
WP_013920974.1\|8177122_8179369_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.6e-166	42.5
WP_013920975.1\|8179346_8180042_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_013920976.1\|8180088_8180334_-	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	1.5e-08	39.2
WP_013920977.1\|8180449_8181343_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	4.5e-42	32.8
WP_013920978.1\|8181376_8182672_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	3.1e-20	25.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017672

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection