CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017735	Helicobacter cetorum MIT 99-5656, complete sequence	0 crisprs	cas14j,DEDDh,cas3,cas10,csx20	0	0	4	0
NC_017736	Helicobacter cetorum MIT 99-5656 plasmid pHCD, complete sequence	0 crisprs	cas14j	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

178673 : 194215

Helicobacter_phage(92.31%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014658737.1\|178673_178988_-	thioredoxin family protein	A0A1X9I9P5	Staphylococcus_phage	4.9e-12	35.4
WP_014658738.1\|179112_180372_+	glycosyl transferase	NA	NA	NA	NA
WP_014658739.1\|181025_181520_+	hypothetical protein	NA	NA	NA	NA
WP_014658740.1\|181530_182292_+	hypothetical protein	A0A1S5RFP7	Helicobacter_phage	5.0e-50	61.5
WP_014658741.1\|182288_182594_-	hypothetical protein	A0A1S5RGB8	Helicobacter_phage	3.0e-06	32.3
WP_014658742.1\|182594_183074_-	hypothetical protein	A0A1S5RFT1	Helicobacter_phage	1.3e-08	32.3
WP_014658743.1\|183086_183533_-	hypothetical protein	A0A1S5RFY6	Helicobacter_phage	6.7e-15	45.5
WP_014658744.1\|183653_184034_-	hypothetical protein	A0A1S5RFY0	Helicobacter_phage	4.5e-12	37.8
WP_014658745.1\|184045_185215_-	DUF4043 family protein	A0A1S5RFH4	Helicobacter_phage	6.5e-134	62.6
WP_041594804.1\|185228_185762_-	hypothetical protein	A0A1S5RG34	Helicobacter_phage	4.8e-44	57.1
WP_014658747.1\|185860_186883_-	hypothetical protein	A0A1S5RFU1	Helicobacter_phage	2.2e-24	41.2
WP_014658748.1\|186996_187578_-	hypothetical protein	A0A1S5RGA2	Helicobacter_phage	1.6e-37	47.4
WP_014658749.1\|187596_188319_-	hypothetical protein	A0A1S5RGV2	Helicobacter_phage	1.4e-09	28.5
WP_014658751.1\|188863_189646_-	hypothetical protein	A0A1S5RFY9	Helicobacter_phage	3.9e-66	54.4
WP_014658753.1\|190574_191027_-	hypothetical protein	NA	NA	NA	NA
WP_144005874.1\|191101_194215_-	DUF3519 domain-containing protein	A0A1S5RF23	Helicobacter_phage	2.0e-275	64.1

DBSCAN-SWA_2

454298 : 519659

Helicobacter_phage(58.33%)

tRNA,transposase,integrase

attL 445176:445193|attR 513367:513384

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
445176:445193	attL	NA	NA	NA	NA
WP_014658986.1\|454298_455924_+\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_014658987.1\|455987_456743_+	HugZ family heme oxygenase	NA	NA	NA	NA
WP_014658988.1\|456966_457494_-	hypothetical protein	NA	NA	NA	NA
WP_158308546.1\|458687_458861_+	hypothetical protein	NA	NA	NA	NA
WP_014658798.1\|458996_460319_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2
WP_014658764.1\|460355_460772_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4
WP_014658990.1\|461032_461296_+	ParA family protein	NA	NA	NA	NA
WP_014658991.1\|461334_461706_+	hypothetical protein	NA	NA	NA	NA
WP_144005835.1\|461692_461929_+	hypothetical protein	NA	NA	NA	NA
WP_144005836.1\|461909_462221_+	hypothetical protein	NA	NA	NA	NA
WP_144005837.1\|462243_462447_+	hypothetical protein	NA	NA	NA	NA
WP_144005838.1\|462543_462858_+	nucleotide-binding protein	NA	NA	NA	NA
WP_158308547.1\|467719_467857_-	hypothetical protein	NA	NA	NA	NA
WP_158308548.1\|468102_468276_-	hypothetical protein	NA	NA	NA	NA
WP_014658994.1\|468413_468638_-	hypothetical protein	NA	NA	NA	NA
WP_014658995.1\|469274_478052_-	vacuolating cytotoxin domain-containing protein	NA	NA	NA	NA
WP_014658996.1\|478113_478587_-	DUF4149 domain-containing protein	NA	NA	NA	NA
WP_014658997.1\|478583_479129_-	pimelyl-ACP methyl ester esterase BioV	NA	NA	NA	NA
WP_162097470.1\|479131_480805_-	AAA family ATPase	E5ESM9	Bathycoccus_sp._RCC1105_virus	7.3e-62	38.9
WP_014658999.1\|480767_482024_-\|tRNA	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase MtaB	NA	NA	NA	NA
WP_014659000.1\|482027_483587_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_014659001.1\|483577_484609_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_014659002.1\|484612_486049_-	potassium transporter TrkA	NA	NA	NA	NA
WP_014659003.1\|486105_487215_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.2e-74	41.4
WP_014659004.1\|487211_488204_-	lipid A biosynthesis lauroyl acyltransferase	NA	NA	NA	NA
WP_014659005.1\|488200_489211_-	lipopolysaccharide heptosyltransferase I	NA	NA	NA	NA
WP_014659006.1\|489207_490662_-	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_014659007.1\|490674_490926_-	YfhL family 4Fe-4S dicluster ferredoxin	NA	NA	NA	NA
WP_014659008.1\|490985_491540_-	indole-3-glycerol-phosphate synthase	NA	NA	NA	NA
WP_014659009.1\|491527_492823_-	ATP-dependent nuclease subunit B	NA	NA	NA	NA
WP_014659010.1\|492864_493263_-	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_014659011.1\|493271_493814_-	hypothetical protein	NA	NA	NA	NA
WP_014659012.1\|493830_494352_-	hypothetical protein	NA	NA	NA	NA
WP_014659013.1\|494341_495319_-	hypothetical protein	NA	NA	NA	NA
WP_014659014.1\|495318_495990_-	DUF374 domain-containing protein	NA	NA	NA	NA
WP_014659015.1\|496003_497314_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_014659016.1\|497323_497566_-	hypothetical protein	NA	NA	NA	NA
WP_014659017.1\|497640_498873_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_014659018.1\|498857_499994_-	dihydroorotase family protein	NA	NA	NA	NA
WP_014659019.1\|500001_500718_-	cytochrome c biogenesis protein CcdA	NA	NA	NA	NA
WP_014659020.1\|500820_503391_-	AAA family ATPase	H6X3M6	Enterobacteria_phage	1.4e-112	35.8
WP_014659021.1\|503474_504233_-	site-specific DNA-methyltransferase	A0A0N9PB81	Sulfolobus_monocaudavirus	5.2e-68	53.8
WP_041594878.1\|504229_504925_-	hypothetical protein	NA	NA	NA	NA
WP_014658798.1\|505113_506436_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2
WP_014658764.1\|506472_506889_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4
WP_014659023.1\|507093_507492_-	hypothetical protein	NA	NA	NA	NA
WP_014659024.1\|507451_507673_-	hypothetical protein	NA	NA	NA	NA
WP_014659025.1\|508218_509199_+	HipA domain-containing protein	NA	NA	NA	NA
WP_014659026.1\|509519_510587_-\|integrase	tyrosine-type recombinase/integrase	S5W9T9	Leptospira_phage	1.3e-08	26.1
WP_158308549.1\|510619_510826_-	hypothetical protein	NA	NA	NA	NA
WP_014659030.1\|515678_516071_-	hypothetical protein	A0A1S5RH76	Helicobacter_phage	6.7e-27	46.1
513367:513384	attR	NA	NA	NA	NA
WP_014659031.1\|516286_516538_-	hypothetical protein	NA	NA	NA	NA
WP_014659032.1\|516534_517689_-	hypothetical protein	A0A1S5RGQ2	Helicobacter_phage	1.0e-91	51.0
WP_014659033.1\|517904_519011_-	Mrp/NBP35 family ATP-binding protein	NA	NA	NA	NA
WP_014658764.1\|519242_519659_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4

DBSCAN-SWA_3

1024652 : 1087455

Helicobacter_phage(81.82%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014659483.1\|1024652_1025681_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_014659484.1\|1025873_1026635_+	J domain-containing protein	NA	NA	NA	NA
WP_144005847.1\|1026631_1027144_-	nicotinate (nicotinamide) nucleotide adenylyltransferase	NA	NA	NA	NA
WP_014659486.1\|1027147_1027594_-	nickel-responsive transcriptional regulator NikR	NA	NA	NA	NA
WP_162097469.1\|1027788_1027980_+	hypothetical protein	NA	NA	NA	NA
WP_014659487.1\|1027949_1028390_+	TonB-system energizer ExbB	NA	NA	NA	NA
WP_014659488.1\|1028386_1028776_+	TonB system transport protein ExbD	NA	NA	NA	NA
WP_014659489.1\|1028741_1029536_+	energy transducer TonB	NA	NA	NA	NA
WP_014659492.1\|1031625_1031817_-	hypothetical protein	NA	NA	NA	NA
WP_014659493.1\|1032689_1033538_+	biotin synthase	NA	NA	NA	NA
WP_014659494.1\|1033537_1034431_+	YihY family inner membrane protein	NA	NA	NA	NA
WP_014659495.1\|1034398_1035097_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_014659496.1\|1035227_1036361_+	ABC transporter permease	NA	NA	NA	NA
WP_014659497.1\|1036377_1037151_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	2.3e-18	31.5
WP_014659498.1\|1037135_1037951_+	MCE family protein	NA	NA	NA	NA
WP_014659499.1\|1037952_1038603_+	hypothetical protein	NA	NA	NA	NA
WP_014659500.1\|1038634_1039222_+	META domain-containing protein	NA	NA	NA	NA
WP_014659501.1\|1039344_1040091_-	DUF535 family protein	NA	NA	NA	NA
WP_014659502.1\|1040360_1041422_-	cytochrome-c peroxidase	NA	NA	NA	NA
WP_014659503.1\|1041574_1045213_+	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	6.2e-191	35.0
WP_041594828.1\|1045194_1045965_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_014659505.1\|1046185_1050835_+	DUF3519 domain-containing protein	A0A1S5RFB0	Helicobacter_phage	9.1e-288	42.5
WP_014659506.1\|1050930_1051383_+	hypothetical protein	NA	NA	NA	NA
WP_014658751.1\|1052311_1053094_+	hypothetical protein	A0A1S5RFY9	Helicobacter_phage	3.9e-66	54.4
WP_014658749.1\|1053638_1054361_+	hypothetical protein	A0A1S5RGV2	Helicobacter_phage	1.4e-09	28.5
WP_014658748.1\|1054379_1054961_+	hypothetical protein	A0A1S5RGA2	Helicobacter_phage	1.6e-37	47.4
WP_014658747.1\|1055074_1056097_+	hypothetical protein	A0A1S5RFU1	Helicobacter_phage	2.2e-24	41.2
WP_041594804.1\|1056195_1056729_+	hypothetical protein	A0A1S5RG34	Helicobacter_phage	4.8e-44	57.1
WP_014658745.1\|1056742_1057912_+	DUF4043 family protein	A0A1S5RFH4	Helicobacter_phage	6.5e-134	62.6
WP_014658744.1\|1057923_1058304_+	hypothetical protein	A0A1S5RFY0	Helicobacter_phage	4.5e-12	37.8
WP_014658743.1\|1058424_1058871_+	hypothetical protein	A0A1S5RFY6	Helicobacter_phage	6.7e-15	45.5
WP_014658742.1\|1058883_1059363_+	hypothetical protein	A0A1S5RFT1	Helicobacter_phage	1.3e-08	32.3
WP_014658741.1\|1059363_1059669_+	hypothetical protein	A0A1S5RGB8	Helicobacter_phage	3.0e-06	32.3
WP_014659507.1\|1059709_1060009_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	5.9e-15	44.6
WP_014659508.1\|1060001_1060322_+	putative addiction module antidote protein	NA	NA	NA	NA
WP_014659509.1\|1060318_1061089_-	hypothetical protein	A0A1S5RFP7	Helicobacter_phage	3.8e-50	61.5
WP_014658739.1\|1061099_1061594_-	hypothetical protein	NA	NA	NA	NA
WP_014659510.1\|1062126_1064331_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_014659511.1\|1064349_1065396_+	DHH family phosphoesterase	NA	NA	NA	NA
WP_014659512.1\|1065481_1066153_-	homeostatic response regulator transcription factor HsrA	NA	NA	NA	NA
WP_014659513.1\|1066498_1067608_-	metallophosphoesterase	NA	NA	NA	NA
WP_081482785.1\|1067686_1068157_-	AlwI family type II restriction endonuclease	NA	NA	NA	NA
WP_014658764.1\|1069722_1070139_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4
WP_014658798.1\|1070175_1071498_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2
WP_014659519.1\|1071877_1073029_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_014659520.1\|1073025_1073508_-	hypothetical protein	NA	NA	NA	NA
WP_014659521.1\|1073507_1075994_-	DNA topoisomerase (ATP-hydrolyzing) subunit A	A0A172JHV7	Bacillus_phage	5.1e-112	33.3
WP_050854978.1\|1076009_1076405_-	diacylglycerol kinase	NA	NA	NA	NA
WP_162097471.1\|1076409_1077369_-	hypothetical protein	NA	NA	NA	NA
WP_014659524.1\|1077437_1078451_-	lipid A deacylase LpxR family protein	NA	NA	NA	NA
WP_014658798.1\|1078742_1080065_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2
WP_014658764.1\|1080101_1080518_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4
WP_014659527.1\|1082648_1083452_-	3'-5' exonuclease	NA	NA	NA	NA
WP_014659528.1\|1083588_1085517_+	ferrous iron transport protein B	NA	NA	NA	NA
WP_014658798.1\|1085679_1087002_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2
WP_014658764.1\|1087038_1087455_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4

DBSCAN-SWA_4

1644682 : 1665829

Helicobacter_phage(75.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014658798.1\|1644682_1646005_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2
WP_014658764.1\|1646041_1646458_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4
WP_173361702.1\|1646620_1649293_+	N-6 DNA methylase	A0A2H4PQP5	Staphylococcus_phage	2.4e-14	29.8
WP_014658798.1\|1650163_1651486_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2
WP_014658764.1\|1651522_1651939_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4
WP_014660022.1\|1652448_1654353_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_144005867.1\|1654971_1655946_-	NAD(P)-binding domain-containing protein	A0A2K9L162	Tupanvirus	1.5e-06	23.2
WP_014660024.1\|1655952_1656165_-	cbb3-type cytochrome oxidase assembly protein CcoS	NA	NA	NA	NA
WP_014660025.1\|1656289_1656871_+	DedA family protein	NA	NA	NA	NA
WP_014660026.1\|1656966_1657461_+	flavodoxin	NA	NA	NA	NA
WP_014660027.1\|1657509_1657932_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_014660028.1\|1658809_1659583_-	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_081482798.1\|1659592_1663219_-	outer membrane protein	NA	NA	NA	NA
WP_014658764.1\|1664053_1664470_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	9.9e-69	88.4
WP_014658798.1\|1664506_1665829_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1S5RHD5	Helicobacter_phage	1.5e-150	77.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage